[{"Gene":"AAAS","Gene synonym":[],"Ensembl":"ENSG00000094914","Gene description":"Aladin WD repeat nucleoporin","Uniprot":["Q9NRG9"],"Chromosome":"12","Position":"53307456-53324864","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040086"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":["Centrosome","Cytosol"],"Antibody RRID":{"HPA040086":"AB_10805602"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.93e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-2"},"Tissue RNA - adipose tissue [nTPM]":"17.0","Tissue RNA - adrenal gland [nTPM]":"36.3","Tissue RNA - amygdala [nTPM]":"12.3","Tissue RNA - appendix [nTPM]":"13.8","Tissue RNA - basal ganglia [nTPM]":"15.0","Tissue RNA - bone marrow [nTPM]":"19.1","Tissue RNA - breast [nTPM]":"17.1","Tissue RNA - cerebellum [nTPM]":"15.2","Tissue RNA - cerebral cortex [nTPM]":"15.6","Tissue RNA - cervix [nTPM]":"20.3","Tissue RNA - choroid plexus [nTPM]":"15.1","Tissue RNA - colon [nTPM]":"19.1","Tissue RNA - duodenum [nTPM]":"12.3","Tissue RNA - endometrium 1 [nTPM]":"19.1","Tissue RNA - epididymis [nTPM]":"7.2","Tissue RNA - esophagus [nTPM]":"19.3","Tissue RNA - fallopian tube [nTPM]":"19.9","Tissue RNA - gallbladder [nTPM]":"9.4","Tissue RNA - heart muscle [nTPM]":"22.7","Tissue RNA - hippocampal formation [nTPM]":"12.9","Tissue RNA - hypothalamus [nTPM]":"13.7","Tissue RNA - kidney [nTPM]":"21.7","Tissue RNA - liver [nTPM]":"24.6","Tissue RNA - lung [nTPM]":"14.0","Tissue RNA - lymph node [nTPM]":"17.6","Tissue RNA - medulla oblongata [nTPM]":"14.3","Tissue RNA - midbrain [nTPM]":"14.1","Tissue RNA - ovary [nTPM]":"19.2","Tissue RNA - pancreas [nTPM]":"23.9","Tissue RNA - parathyroid gland [nTPM]":"18.0","Tissue RNA - pituitary gland [nTPM]":"24.8","Tissue RNA - placenta [nTPM]":"17.4","Tissue RNA - pons [nTPM]":"14.8","Tissue RNA - prostate [nTPM]":"18.4","Tissue RNA - rectum [nTPM]":"15.1","Tissue RNA - retina [nTPM]":"12.3","Tissue RNA - salivary gland [nTPM]":"18.5","Tissue RNA - seminal vesicle [nTPM]":"11.7","Tissue RNA - skeletal muscle [nTPM]":"22.6","Tissue RNA - skin 1 [nTPM]":"17.3","Tissue RNA - small intestine [nTPM]":"17.7","Tissue RNA - smooth muscle [nTPM]":"16.8","Tissue RNA - spinal cord [nTPM]":"13.7","Tissue RNA - spleen [nTPM]":"22.2","Tissue RNA - stomach 1 [nTPM]":"21.6","Tissue RNA - testis [nTPM]":"27.3","Tissue RNA - thalamus [nTPM]":"14.0","Tissue RNA - thymus [nTPM]":"25.2","Tissue RNA - thyroid gland [nTPM]":"19.4","Tissue RNA - tongue [nTPM]":"18.5","Tissue RNA - tonsil [nTPM]":"21.6","Tissue RNA - urinary bladder [nTPM]":"17.8","Tissue RNA - vagina [nTPM]":"17.9","Tissue RNA - white matter [nTPM]":"17.2","Cell RNA - A-431 [nTPM]":"26.1","Cell RNA - A549 [nTPM]":"77.3","Cell RNA - AF22 [nTPM]":"63.2","Cell RNA - AN3-CA [nTPM]":"38.0","Cell RNA - ASC diff [nTPM]":"28.6","Cell RNA - ASC TERT1 [nTPM]":"32.2","Cell RNA - BEWO [nTPM]":"38.9","Cell RNA - BJ [nTPM]":"29.8","Cell RNA - BJ hTERT+ [nTPM]":"31.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"72.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"42.1","Cell RNA - CACO-2 [nTPM]":"54.0","Cell RNA - CAPAN-2 [nTPM]":"56.7","Cell RNA - Daudi [nTPM]":"62.2","Cell RNA - EFO-21 [nTPM]":"47.4","Cell RNA - fHDF\/TERT166 [nTPM]":"37.3","Cell RNA - GAMG [nTPM]":"41.9","Cell RNA - HaCaT [nTPM]":"37.6","Cell RNA - HAP1 [nTPM]":"106.4","Cell RNA - HBEC3-KT [nTPM]":"78.8","Cell RNA - HBF TERT88 [nTPM]":"42.1","Cell RNA - HDLM-2 [nTPM]":"41.0","Cell RNA - HEK 293 [nTPM]":"68.1","Cell RNA - HEL [nTPM]":"49.7","Cell RNA - HeLa [nTPM]":"29.9","Cell RNA - Hep G2 [nTPM]":"40.7","Cell RNA - HHSteC [nTPM]":"26.4","Cell RNA - HL-60 [nTPM]":"45.5","Cell RNA - HMC-1 [nTPM]":"37.9","Cell RNA - HSkMC [nTPM]":"28.1","Cell RNA - hTCEpi [nTPM]":"39.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"48.9","Cell RNA - hTERT-HME1 [nTPM]":"44.6","Cell RNA - hTERT-RPE1 [nTPM]":"40.4","Cell RNA - HUVEC TERT2 [nTPM]":"56.6","Cell RNA - JURKAT [nTPM]":"56.2","Cell RNA - K-562 [nTPM]":"67.6","Cell RNA - Karpas-707 [nTPM]":"70.6","Cell RNA - LHCN-M2 [nTPM]":"30.4","Cell RNA - MCF7 [nTPM]":"72.8","Cell RNA - MOLT-4 [nTPM]":"71.2","Cell RNA - NB-4 [nTPM]":"46.1","Cell RNA - NTERA-2 [nTPM]":"40.0","Cell RNA - OE19 [nTPM]":"27.7","Cell RNA - PC-3 [nTPM]":"53.1","Cell RNA - REH [nTPM]":"72.1","Cell RNA - RH-30 [nTPM]":"39.3","Cell RNA - RPMI-8226 [nTPM]":"69.4","Cell RNA - RPTEC TERT1 [nTPM]":"38.2","Cell RNA - RT4 [nTPM]":"17.5","Cell RNA - SCLC-21H [nTPM]":"32.8","Cell RNA - SH-SY5Y [nTPM]":"41.3","Cell RNA - SiHa [nTPM]":"20.2","Cell RNA - SK-BR-3 [nTPM]":"46.9","Cell RNA - SK-MEL-30 [nTPM]":"21.0","Cell RNA - SuSa [nTPM]":"40.2","Cell RNA - T-47d [nTPM]":"61.2","Cell RNA - THP-1 [nTPM]":"38.8","Cell RNA - TIME [nTPM]":"25.5","Cell RNA - U-138 MG [nTPM]":"34.9","Cell RNA - U-2 OS [nTPM]":"51.1","Cell RNA - U-2197 [nTPM]":"27.4","Cell RNA - U-251 MG [nTPM]":"32.9","Cell RNA - U-266\/70 [nTPM]":"32.5","Cell RNA - U-266\/84 [nTPM]":"43.5","Cell RNA - U-698 [nTPM]":"54.7","Cell RNA - U-87 MG [nTPM]":"25.6","Cell RNA - U-937 [nTPM]":"39.6","Cell RNA - WM-115 [nTPM]":"40.5","Blood RNA - basophil [nTPM]":"1.0","Blood RNA - classical monocyte [nTPM]":"17.7","Blood RNA - eosinophil [nTPM]":"10.7","Blood RNA - gdT-cell [nTPM]":"18.4","Blood RNA - intermediate monocyte [nTPM]":"20.2","Blood RNA - MAIT T-cell [nTPM]":"20.8","Blood RNA - memory B-cell [nTPM]":"20.0","Blood RNA - memory CD4 T-cell [nTPM]":"15.9","Blood RNA - memory CD8 T-cell [nTPM]":"16.8","Blood RNA - myeloid DC [nTPM]":"18.8","Blood RNA - naive B-cell [nTPM]":"21.8","Blood RNA - naive CD4 T-cell [nTPM]":"21.7","Blood RNA - naive CD8 T-cell [nTPM]":"21.4","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"10.5","Blood RNA - non-classical monocyte [nTPM]":"22.5","Blood RNA - plasmacytoid DC [nTPM]":"22.6","Blood RNA - T-reg [nTPM]":"17.4","Blood RNA - total PBMC [nTPM]":"15.2","Brain RNA - amygdala [nTPM]":"12.3","Brain RNA - basal ganglia [nTPM]":"15.0","Brain RNA - cerebellum [nTPM]":"15.2","Brain RNA - cerebral cortex [nTPM]":"15.6","Brain RNA - hippocampal formation [nTPM]":"12.9","Brain RNA - hypothalamus [nTPM]":"13.7","Brain RNA - medulla oblongata [nTPM]":"14.3","Brain RNA - midbrain [nTPM]":"14.1","Brain RNA - pons [nTPM]":"14.8","Brain RNA - spinal cord [nTPM]":"13.7","Brain RNA - thalamus [nTPM]":"14.0","Brain RNA - white matter [nTPM]":"17.2","Single Cell Type RNA - Adipocytes [nTPM]":"11.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.8","Single Cell Type RNA - Astrocytes [nTPM]":"17.9","Single Cell Type RNA - B-cells [nTPM]":"15.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"19.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"26.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"11.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"15.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"58.4","Single Cell Type RNA - dendritic cells [nTPM]":"13.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"20.4","Single Cell Type RNA - Early spermatids [nTPM]":"12.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.9","Single Cell Type RNA - Endothelial cells [nTPM]":"11.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"41.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"49.5","Single Cell Type RNA - Fibroblasts [nTPM]":"14.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.9","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"13.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"12.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.5","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.1","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"12.4","Single Cell Type RNA - Langerhans cells [nTPM]":"9.3","Single Cell Type RNA - Late spermatids [nTPM]":"26.2","Single Cell Type RNA - Leydig cells [nTPM]":"17.7","Single Cell Type RNA - Macrophages [nTPM]":"10.6","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"11.6","Single Cell Type RNA - Muller glia cells [nTPM]":"18.0","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.9","Single Cell Type RNA - Paneth cells [nTPM]":"11.0","Single Cell Type RNA - Peritubular cells [nTPM]":"12.8","Single Cell Type RNA - Plasma cells [nTPM]":"20.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.5","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"39.7","Single Cell Type RNA - Spermatocytes [nTPM]":"34.2","Single Cell Type RNA - Spermatogonia [nTPM]":"40.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"36.5","Single Cell Type RNA - T-cells [nTPM]":"11.4","Single Cell Type RNA - Theca cells [nTPM]":"14.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.2","Single Cell Type RNA - Urothelial cells [nTPM]":"13.0"},{"Gene":"AARS1","Gene synonym":["AARS","AlaRS","CMT2N"],"Ensembl":"ENSG00000090861","Gene description":"Alanyl-tRNA synthetase 1","Uniprot":["P49588"],"Chromosome":"16","Position":"70251983-70289707","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase","RNA-binding","tRNA-binding"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Epilepsy","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Cardiomyocytes":"25.1","Cytotrophoblasts":"63.0","Extravillous trophoblasts":"29.9","Hofbauer cells":"27.1","Syncytiotrophoblasts":"52.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034261","HPA040870","HPA044223"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"620000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB034261":"AB_1562673","HPA040870":"AB_10794995","HPA044223":"AB_2678862"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-3"},"Tissue RNA - adipose tissue [nTPM]":"43.7","Tissue RNA - adrenal gland [nTPM]":"54.7","Tissue RNA - amygdala [nTPM]":"60.1","Tissue RNA - appendix [nTPM]":"33.4","Tissue RNA - basal ganglia [nTPM]":"64.3","Tissue RNA - bone marrow [nTPM]":"7.9","Tissue RNA - breast [nTPM]":"41.4","Tissue RNA - cerebellum [nTPM]":"73.3","Tissue RNA - cerebral cortex [nTPM]":"88.6","Tissue RNA - cervix [nTPM]":"42.1","Tissue RNA - choroid plexus [nTPM]":"49.2","Tissue RNA - colon [nTPM]":"48.9","Tissue RNA - duodenum [nTPM]":"26.0","Tissue RNA - endometrium 1 [nTPM]":"49.8","Tissue RNA - epididymis [nTPM]":"49.6","Tissue RNA - esophagus [nTPM]":"29.5","Tissue RNA - fallopian tube [nTPM]":"40.4","Tissue RNA - gallbladder [nTPM]":"22.3","Tissue RNA - heart muscle [nTPM]":"47.9","Tissue RNA - hippocampal formation [nTPM]":"62.8","Tissue RNA - hypothalamus [nTPM]":"71.7","Tissue RNA - kidney [nTPM]":"43.6","Tissue RNA - liver [nTPM]":"72.0","Tissue RNA - lung [nTPM]":"45.3","Tissue RNA - lymph node [nTPM]":"30.0","Tissue RNA - medulla oblongata [nTPM]":"78.6","Tissue RNA - midbrain [nTPM]":"68.6","Tissue RNA - ovary [nTPM]":"37.3","Tissue RNA - pancreas [nTPM]":"75.8","Tissue RNA - parathyroid gland [nTPM]":"74.9","Tissue RNA - pituitary gland [nTPM]":"50.1","Tissue RNA - placenta [nTPM]":"35.6","Tissue RNA - pons [nTPM]":"84.9","Tissue RNA - prostate [nTPM]":"40.0","Tissue RNA - rectum [nTPM]":"26.2","Tissue RNA - retina [nTPM]":"59.3","Tissue RNA - salivary gland [nTPM]":"53.3","Tissue RNA - seminal vesicle [nTPM]":"47.2","Tissue RNA - skeletal muscle [nTPM]":"62.4","Tissue RNA - skin 1 [nTPM]":"28.8","Tissue RNA - small intestine [nTPM]":"32.7","Tissue RNA - smooth muscle [nTPM]":"47.8","Tissue RNA - spinal cord [nTPM]":"66.3","Tissue RNA - spleen [nTPM]":"38.3","Tissue RNA - stomach 1 [nTPM]":"51.8","Tissue RNA - testis [nTPM]":"23.8","Tissue RNA - thalamus [nTPM]":"74.8","Tissue RNA - thymus [nTPM]":"36.4","Tissue RNA - thyroid gland [nTPM]":"66.6","Tissue RNA - tongue [nTPM]":"39.7","Tissue RNA - tonsil [nTPM]":"35.5","Tissue RNA - urinary bladder [nTPM]":"45.9","Tissue RNA - vagina [nTPM]":"32.8","Tissue RNA - white matter [nTPM]":"83.9","Cell RNA - A-431 [nTPM]":"123.7","Cell RNA - A549 [nTPM]":"192.8","Cell RNA - AF22 [nTPM]":"52.9","Cell RNA - AN3-CA [nTPM]":"205.7","Cell RNA - ASC diff [nTPM]":"127.3","Cell RNA - ASC TERT1 [nTPM]":"115.0","Cell RNA - BEWO [nTPM]":"125.7","Cell RNA - BJ [nTPM]":"97.7","Cell RNA - BJ hTERT+ [nTPM]":"135.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"119.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"151.8","Cell RNA - CACO-2 [nTPM]":"162.5","Cell RNA - CAPAN-2 [nTPM]":"163.2","Cell RNA - Daudi [nTPM]":"140.4","Cell RNA - EFO-21 [nTPM]":"127.2","Cell RNA - fHDF\/TERT166 [nTPM]":"99.3","Cell RNA - GAMG [nTPM]":"90.8","Cell RNA - HaCaT [nTPM]":"137.2","Cell RNA - HAP1 [nTPM]":"160.5","Cell RNA - HBEC3-KT [nTPM]":"133.1","Cell RNA - HBF TERT88 [nTPM]":"170.7","Cell RNA - HDLM-2 [nTPM]":"63.2","Cell RNA - HEK 293 [nTPM]":"54.7","Cell RNA - HEL [nTPM]":"135.6","Cell RNA - HeLa [nTPM]":"78.0","Cell RNA - Hep G2 [nTPM]":"152.2","Cell RNA - HHSteC [nTPM]":"348.0","Cell RNA - HL-60 [nTPM]":"74.4","Cell RNA - HMC-1 [nTPM]":"77.2","Cell RNA - HSkMC [nTPM]":"133.9","Cell RNA - hTCEpi [nTPM]":"193.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"228.1","Cell RNA - hTERT-HME1 [nTPM]":"508.4","Cell RNA - hTERT-RPE1 [nTPM]":"91.4","Cell RNA - HUVEC TERT2 [nTPM]":"120.3","Cell RNA - JURKAT [nTPM]":"209.3","Cell RNA - K-562 [nTPM]":"176.0","Cell RNA - Karpas-707 [nTPM]":"173.4","Cell RNA - LHCN-M2 [nTPM]":"91.3","Cell RNA - MCF7 [nTPM]":"282.0","Cell RNA - MOLT-4 [nTPM]":"89.4","Cell RNA - NB-4 [nTPM]":"85.0","Cell RNA - NTERA-2 [nTPM]":"104.3","Cell RNA - OE19 [nTPM]":"160.0","Cell RNA - PC-3 [nTPM]":"108.5","Cell RNA - REH [nTPM]":"170.4","Cell RNA - RH-30 [nTPM]":"36.1","Cell RNA - RPMI-8226 [nTPM]":"317.0","Cell RNA - RPTEC TERT1 [nTPM]":"84.7","Cell RNA - RT4 [nTPM]":"60.3","Cell RNA - SCLC-21H [nTPM]":"67.9","Cell RNA - SH-SY5Y [nTPM]":"57.3","Cell RNA - SiHa [nTPM]":"269.5","Cell RNA - SK-BR-3 [nTPM]":"62.3","Cell RNA - SK-MEL-30 [nTPM]":"246.1","Cell RNA - SuSa [nTPM]":"75.8","Cell RNA - T-47d [nTPM]":"197.7","Cell RNA - THP-1 [nTPM]":"181.3","Cell RNA - TIME [nTPM]":"75.2","Cell RNA - U-138 MG [nTPM]":"85.2","Cell RNA - U-2 OS [nTPM]":"82.9","Cell RNA - U-2197 [nTPM]":"84.9","Cell RNA - U-251 MG [nTPM]":"78.8","Cell RNA - U-266\/70 [nTPM]":"233.8","Cell RNA - U-266\/84 [nTPM]":"174.2","Cell RNA - U-698 [nTPM]":"258.2","Cell RNA - U-87 MG [nTPM]":"155.4","Cell RNA - U-937 [nTPM]":"124.9","Cell RNA - WM-115 [nTPM]":"175.9","Blood RNA - basophil [nTPM]":"6.5","Blood RNA - classical monocyte [nTPM]":"7.8","Blood RNA - eosinophil [nTPM]":"2.7","Blood RNA - gdT-cell [nTPM]":"11.9","Blood RNA - intermediate monocyte [nTPM]":"13.2","Blood RNA - MAIT T-cell [nTPM]":"13.0","Blood RNA - memory B-cell [nTPM]":"12.8","Blood RNA - memory CD4 T-cell [nTPM]":"9.7","Blood RNA - memory CD8 T-cell [nTPM]":"11.7","Blood RNA - myeloid DC [nTPM]":"11.9","Blood RNA - naive B-cell [nTPM]":"9.1","Blood RNA - naive CD4 T-cell [nTPM]":"11.2","Blood RNA - naive CD8 T-cell [nTPM]":"12.2","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"22.7","Blood RNA - non-classical monocyte [nTPM]":"14.1","Blood RNA - plasmacytoid DC [nTPM]":"7.0","Blood RNA - T-reg [nTPM]":"8.0","Blood RNA - total PBMC [nTPM]":"12.6","Brain RNA - amygdala [nTPM]":"60.1","Brain RNA - basal ganglia [nTPM]":"64.3","Brain RNA - cerebellum [nTPM]":"73.3","Brain RNA - cerebral cortex [nTPM]":"88.6","Brain RNA - hippocampal formation [nTPM]":"62.8","Brain RNA - hypothalamus [nTPM]":"71.7","Brain RNA - medulla oblongata [nTPM]":"78.6","Brain RNA - midbrain [nTPM]":"68.6","Brain RNA - pons [nTPM]":"84.9","Brain RNA - spinal cord [nTPM]":"66.3","Brain RNA - thalamus [nTPM]":"74.8","Brain RNA - white matter [nTPM]":"83.9","Single Cell Type RNA - Adipocytes [nTPM]":"6.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"63.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"3.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"29.9","Single Cell Type RNA - Fibroblasts [nTPM]":"4.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"27.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"52.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"AARS2","Gene synonym":["AARSL","bA444E17.1","KIAA1270"],"Ensembl":"ENSG00000124608","Gene description":"Alanyl-tRNA synthetase 2, mitochondrial","Uniprot":["Q5JTZ9"],"Chromosome":"6","Position":"44298731-44313347","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase","RNA-binding","tRNA-binding"],"Disease involvement":["Cancer-related genes","Cardiomyopathy","Disease variant","Neurodegeneration","Premature ovarian failure","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035636","HPA061396"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 23: Spermatids - Flagellum & Golgi organization","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA035636":"AB_10670837","HPA061396":"AB_2684502"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Tissue RNA - adipose tissue [nTPM]":"4.7","Tissue RNA - adrenal gland [nTPM]":"5.2","Tissue RNA - amygdala [nTPM]":"6.5","Tissue RNA - appendix [nTPM]":"5.6","Tissue RNA - basal ganglia [nTPM]":"6.2","Tissue RNA - bone marrow [nTPM]":"5.4","Tissue RNA - breast [nTPM]":"4.9","Tissue RNA - cerebellum [nTPM]":"9.4","Tissue RNA - cerebral cortex [nTPM]":"6.7","Tissue RNA - cervix [nTPM]":"7.6","Tissue RNA - choroid plexus [nTPM]":"6.7","Tissue RNA - colon [nTPM]":"5.8","Tissue RNA - duodenum [nTPM]":"6.5","Tissue RNA - endometrium 1 [nTPM]":"6.1","Tissue RNA - epididymis [nTPM]":"3.2","Tissue RNA - esophagus [nTPM]":"9.2","Tissue RNA - fallopian tube [nTPM]":"6.4","Tissue RNA - gallbladder [nTPM]":"4.6","Tissue RNA - heart muscle [nTPM]":"6.0","Tissue RNA - hippocampal formation [nTPM]":"6.8","Tissue RNA - hypothalamus [nTPM]":"5.1","Tissue RNA - kidney [nTPM]":"5.7","Tissue RNA - liver [nTPM]":"6.9","Tissue RNA - lung [nTPM]":"4.3","Tissue RNA - lymph node [nTPM]":"6.0","Tissue RNA - medulla oblongata [nTPM]":"6.1","Tissue RNA - midbrain [nTPM]":"5.8","Tissue RNA - ovary [nTPM]":"8.3","Tissue RNA - pancreas [nTPM]":"6.5","Tissue RNA - parathyroid gland [nTPM]":"5.9","Tissue RNA - pituitary gland [nTPM]":"6.3","Tissue RNA - placenta [nTPM]":"4.1","Tissue RNA - pons [nTPM]":"6.4","Tissue RNA - prostate [nTPM]":"7.0","Tissue RNA - rectum [nTPM]":"4.1","Tissue RNA - retina [nTPM]":"5.4","Tissue RNA - salivary gland [nTPM]":"6.2","Tissue RNA - seminal vesicle [nTPM]":"4.3","Tissue RNA - skeletal muscle [nTPM]":"4.8","Tissue RNA - skin 1 [nTPM]":"7.2","Tissue RNA - small intestine [nTPM]":"7.9","Tissue RNA - smooth muscle [nTPM]":"4.1","Tissue RNA - spinal cord [nTPM]":"5.4","Tissue RNA - spleen [nTPM]":"7.2","Tissue RNA - stomach 1 [nTPM]":"5.4","Tissue RNA - testis [nTPM]":"3.7","Tissue RNA - thalamus [nTPM]":"6.0","Tissue RNA - thymus [nTPM]":"6.2","Tissue RNA - thyroid gland [nTPM]":"6.2","Tissue RNA - tongue [nTPM]":"3.3","Tissue RNA - tonsil [nTPM]":"5.3","Tissue RNA - urinary bladder [nTPM]":"5.6","Tissue RNA - vagina [nTPM]":"7.4","Tissue RNA - white matter [nTPM]":"6.7","Cell RNA - A-431 [nTPM]":"14.6","Cell RNA - A549 [nTPM]":"9.9","Cell RNA - AF22 [nTPM]":"13.9","Cell RNA - AN3-CA [nTPM]":"23.8","Cell RNA - ASC diff [nTPM]":"8.1","Cell RNA - ASC TERT1 [nTPM]":"7.2","Cell RNA - BEWO [nTPM]":"18.3","Cell RNA - BJ [nTPM]":"10.9","Cell RNA - BJ hTERT+ [nTPM]":"5.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.6","Cell RNA - CACO-2 [nTPM]":"11.4","Cell RNA - CAPAN-2 [nTPM]":"7.1","Cell RNA - Daudi [nTPM]":"16.3","Cell RNA - EFO-21 [nTPM]":"16.2","Cell RNA - fHDF\/TERT166 [nTPM]":"4.8","Cell RNA - GAMG [nTPM]":"12.2","Cell RNA - HaCaT [nTPM]":"10.0","Cell RNA - HAP1 [nTPM]":"14.7","Cell RNA - HBEC3-KT [nTPM]":"16.0","Cell RNA - HBF TERT88 [nTPM]":"4.7","Cell RNA - HDLM-2 [nTPM]":"10.9","Cell RNA - HEK 293 [nTPM]":"23.7","Cell RNA - HEL [nTPM]":"18.9","Cell RNA - HeLa [nTPM]":"10.6","Cell RNA - Hep G2 [nTPM]":"14.5","Cell RNA - HHSteC [nTPM]":"4.8","Cell RNA - HL-60 [nTPM]":"17.9","Cell RNA - HMC-1 [nTPM]":"16.0","Cell RNA - HSkMC [nTPM]":"5.9","Cell RNA - hTCEpi [nTPM]":"9.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.0","Cell RNA - hTERT-HME1 [nTPM]":"10.2","Cell RNA - hTERT-RPE1 [nTPM]":"7.3","Cell RNA - HUVEC TERT2 [nTPM]":"9.5","Cell RNA - JURKAT [nTPM]":"21.8","Cell RNA - K-562 [nTPM]":"21.0","Cell RNA - Karpas-707 [nTPM]":"15.4","Cell RNA - LHCN-M2 [nTPM]":"6.2","Cell RNA - MCF7 [nTPM]":"16.0","Cell RNA - MOLT-4 [nTPM]":"14.2","Cell RNA - NB-4 [nTPM]":"15.9","Cell RNA - NTERA-2 [nTPM]":"9.9","Cell RNA - OE19 [nTPM]":"40.3","Cell RNA - PC-3 [nTPM]":"9.8","Cell RNA - REH [nTPM]":"16.4","Cell RNA - RH-30 [nTPM]":"8.7","Cell RNA - RPMI-8226 [nTPM]":"10.4","Cell RNA - RPTEC TERT1 [nTPM]":"6.7","Cell RNA - RT4 [nTPM]":"12.7","Cell RNA - SCLC-21H [nTPM]":"32.0","Cell RNA - SH-SY5Y [nTPM]":"11.4","Cell RNA - SiHa [nTPM]":"9.4","Cell RNA - SK-BR-3 [nTPM]":"10.9","Cell RNA - SK-MEL-30 [nTPM]":"15.5","Cell RNA - SuSa [nTPM]":"9.7","Cell RNA - T-47d [nTPM]":"9.9","Cell RNA - THP-1 [nTPM]":"21.6","Cell RNA - TIME [nTPM]":"8.4","Cell RNA - U-138 MG [nTPM]":"12.1","Cell RNA - U-2 OS [nTPM]":"13.5","Cell RNA - U-2197 [nTPM]":"7.6","Cell RNA - U-251 MG [nTPM]":"13.9","Cell RNA - U-266\/70 [nTPM]":"8.8","Cell RNA - U-266\/84 [nTPM]":"8.7","Cell RNA - U-698 [nTPM]":"16.5","Cell RNA - U-87 MG [nTPM]":"6.8","Cell RNA - U-937 [nTPM]":"15.9","Cell RNA - WM-115 [nTPM]":"22.1","Blood RNA - basophil [nTPM]":"2.2","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"1.3","Blood RNA - intermediate monocyte [nTPM]":"1.3","Blood RNA - MAIT T-cell [nTPM]":"2.1","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"1.0","Blood RNA - naive B-cell [nTPM]":"2.9","Blood RNA - naive CD4 T-cell [nTPM]":"1.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.7","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"1.9","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"1.3","Brain RNA - amygdala [nTPM]":"6.5","Brain RNA - basal ganglia [nTPM]":"6.2","Brain RNA - cerebellum [nTPM]":"9.4","Brain RNA - cerebral cortex [nTPM]":"6.7","Brain RNA - hippocampal formation [nTPM]":"6.8","Brain RNA - hypothalamus [nTPM]":"5.1","Brain RNA - medulla oblongata [nTPM]":"6.1","Brain RNA - midbrain [nTPM]":"5.8","Brain RNA - pons [nTPM]":"6.4","Brain RNA - spinal cord [nTPM]":"5.4","Brain RNA - thalamus [nTPM]":"6.0","Brain RNA - white matter [nTPM]":"6.7","Single Cell Type RNA - Adipocytes [nTPM]":"2.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.3","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"3.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"6.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"2.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.0","Single Cell Type RNA - dendritic cells [nTPM]":"4.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.3","Single Cell Type RNA - Early spermatids [nTPM]":"10.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.4","Single Cell Type RNA - Endothelial cells [nTPM]":"3.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"8.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.0","Single Cell Type RNA - Fibroblasts [nTPM]":"3.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"5.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"2.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.2","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.8","Single Cell Type RNA - Langerhans cells [nTPM]":"1.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"4.7","Single Cell Type RNA - Macrophages [nTPM]":"2.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"3.9","Single Cell Type RNA - Muller glia cells [nTPM]":"2.0","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.7","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"6.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.8","Single Cell Type RNA - Spermatocytes [nTPM]":"4.3","Single Cell Type RNA - Spermatogonia [nTPM]":"6.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.3","Single Cell Type RNA - T-cells [nTPM]":"4.1","Single Cell Type RNA - Theca cells [nTPM]":"4.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.7","Single Cell Type RNA - Urothelial cells [nTPM]":"1.6"},{"Gene":"AASS","Gene synonym":["LKRSDH","LORSDH"],"Ensembl":"ENSG00000008311","Gene description":"Aminoadipate-semialdehyde synthase","Uniprot":["Q9UDR5"],"Chromosome":"7","Position":"122064583-122144308","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Multifunctional enzyme","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"44.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"145.9","Hepatocytes":"113.9","Oligodendrocyte precursor cells":"106.1","Oligodendrocytes":"132.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AN3-CA":"41.5","NTERA-2":"55.3","SuSa":"37.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020637","HPA020728","HPA020734"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Mitochondria"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"19000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm","Vesicles"],"Antibody RRID":{"HPA020637":"AB_1844415","HPA020728":"AB_1844416","HPA020734":"AB_1844417"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.81e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.7","Tissue RNA - adrenal gland [nTPM]":"5.9","Tissue RNA - amygdala [nTPM]":"10.0","Tissue RNA - appendix [nTPM]":"1.8","Tissue RNA - basal ganglia [nTPM]":"12.2","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"8.4","Tissue RNA - cerebellum [nTPM]":"10.3","Tissue RNA - cerebral cortex [nTPM]":"14.4","Tissue RNA - cervix [nTPM]":"8.2","Tissue RNA - choroid plexus [nTPM]":"15.5","Tissue RNA - colon [nTPM]":"5.2","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"9.5","Tissue RNA - epididymis [nTPM]":"7.5","Tissue RNA - esophagus [nTPM]":"3.2","Tissue RNA - fallopian tube [nTPM]":"11.7","Tissue RNA - gallbladder [nTPM]":"2.1","Tissue RNA - heart muscle [nTPM]":"9.2","Tissue RNA - hippocampal formation [nTPM]":"9.4","Tissue RNA - hypothalamus [nTPM]":"10.6","Tissue RNA - kidney [nTPM]":"13.9","Tissue RNA - liver [nTPM]":"44.3","Tissue RNA - lung [nTPM]":"6.3","Tissue RNA - lymph node [nTPM]":"1.4","Tissue RNA - medulla oblongata [nTPM]":"11.6","Tissue RNA - midbrain [nTPM]":"11.0","Tissue RNA - ovary [nTPM]":"25.2","Tissue RNA - pancreas [nTPM]":"4.8","Tissue RNA - parathyroid gland [nTPM]":"7.1","Tissue RNA - pituitary gland [nTPM]":"3.5","Tissue RNA - placenta [nTPM]":"3.2","Tissue RNA - pons [nTPM]":"11.4","Tissue RNA - prostate [nTPM]":"5.4","Tissue RNA - rectum [nTPM]":"1.4","Tissue RNA - retina [nTPM]":"3.7","Tissue RNA - salivary gland [nTPM]":"3.5","Tissue RNA - seminal vesicle [nTPM]":"4.8","Tissue RNA - skeletal muscle [nTPM]":"8.6","Tissue RNA - skin 1 [nTPM]":"2.8","Tissue RNA - small intestine [nTPM]":"3.6","Tissue RNA - smooth muscle [nTPM]":"4.4","Tissue RNA - spinal cord [nTPM]":"10.1","Tissue RNA - spleen [nTPM]":"2.9","Tissue RNA - stomach 1 [nTPM]":"5.5","Tissue RNA - testis [nTPM]":"2.2","Tissue RNA - thalamus [nTPM]":"11.0","Tissue RNA - thymus [nTPM]":"1.5","Tissue RNA - thyroid gland [nTPM]":"4.7","Tissue RNA - tongue [nTPM]":"6.2","Tissue RNA - tonsil [nTPM]":"1.4","Tissue RNA - urinary bladder [nTPM]":"6.9","Tissue RNA - vagina [nTPM]":"6.2","Tissue RNA - white matter [nTPM]":"11.8","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"21.9","Cell RNA - AN3-CA [nTPM]":"41.5","Cell RNA - ASC diff [nTPM]":"27.3","Cell RNA - ASC TERT1 [nTPM]":"13.5","Cell RNA - BEWO [nTPM]":"9.4","Cell RNA - BJ [nTPM]":"5.4","Cell RNA - BJ hTERT+ [nTPM]":"8.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.1","Cell RNA - CACO-2 [nTPM]":"12.6","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"6.6","Cell RNA - GAMG [nTPM]":"8.3","Cell RNA - HaCaT [nTPM]":"4.1","Cell RNA - HAP1 [nTPM]":"33.5","Cell RNA - HBEC3-KT [nTPM]":"16.8","Cell RNA - HBF TERT88 [nTPM]":"9.6","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"12.2","Cell RNA - HEL [nTPM]":"9.4","Cell RNA - HeLa [nTPM]":"4.3","Cell RNA - Hep G2 [nTPM]":"12.5","Cell RNA - HHSteC [nTPM]":"22.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"2.9","Cell RNA - HSkMC [nTPM]":"12.2","Cell RNA - hTCEpi [nTPM]":"0.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.2","Cell RNA - hTERT-HME1 [nTPM]":"7.1","Cell RNA - hTERT-RPE1 [nTPM]":"18.9","Cell RNA - HUVEC TERT2 [nTPM]":"19.8","Cell RNA - JURKAT [nTPM]":"12.1","Cell RNA - K-562 [nTPM]":"2.7","Cell RNA - Karpas-707 [nTPM]":"15.5","Cell RNA - LHCN-M2 [nTPM]":"5.1","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.9","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"55.3","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"1.7","Cell RNA - REH [nTPM]":"11.8","Cell RNA - RH-30 [nTPM]":"16.3","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"5.3","Cell RNA - RT4 [nTPM]":"2.4","Cell RNA - SCLC-21H [nTPM]":"2.7","Cell RNA - SH-SY5Y [nTPM]":"0.7","Cell RNA - SiHa [nTPM]":"1.5","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"5.3","Cell RNA - SuSa [nTPM]":"37.8","Cell RNA - T-47d [nTPM]":"0.5","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"8.1","Cell RNA - U-138 MG [nTPM]":"13.6","Cell RNA - U-2 OS [nTPM]":"3.4","Cell RNA - U-2197 [nTPM]":"7.0","Cell RNA - U-251 MG [nTPM]":"8.3","Cell RNA - U-266\/70 [nTPM]":"3.5","Cell RNA - U-266\/84 [nTPM]":"3.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"4.9","Cell RNA - U-937 [nTPM]":"0.8","Cell RNA - WM-115 [nTPM]":"5.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"10.0","Brain RNA - basal ganglia [nTPM]":"12.2","Brain RNA - cerebellum [nTPM]":"10.3","Brain RNA - cerebral cortex [nTPM]":"14.4","Brain RNA - hippocampal formation [nTPM]":"9.4","Brain RNA - hypothalamus [nTPM]":"10.6","Brain RNA - medulla oblongata [nTPM]":"11.6","Brain RNA - midbrain [nTPM]":"11.0","Brain RNA - pons [nTPM]":"11.4","Brain RNA - spinal cord [nTPM]":"10.1","Brain RNA - thalamus [nTPM]":"11.0","Brain RNA - white matter [nTPM]":"11.8","Single Cell Type RNA - Adipocytes [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"37.8","Single Cell Type RNA - Astrocytes [nTPM]":"145.9","Single Cell Type RNA - B-cells [nTPM]":"2.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"7.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"5.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.6","Single Cell Type RNA - dendritic cells [nTPM]":"1.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.7","Single Cell Type RNA - Early spermatids [nTPM]":"12.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"24.0","Single Cell Type RNA - Endothelial cells [nTPM]":"11.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.3","Single Cell Type RNA - Fibroblasts [nTPM]":"14.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.7","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"18.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"24.7","Single Cell Type RNA - Hepatocytes [nTPM]":"113.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.5","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.6","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.2","Single Cell Type RNA - Langerhans cells [nTPM]":"2.5","Single Cell Type RNA - Late spermatids [nTPM]":"7.4","Single Cell Type RNA - Leydig cells [nTPM]":"19.0","Single Cell Type RNA - Macrophages [nTPM]":"1.4","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"35.6","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"8.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"106.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"132.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.3","Single Cell Type RNA - Paneth cells [nTPM]":"2.5","Single Cell Type RNA - Peritubular cells [nTPM]":"24.5","Single Cell Type RNA - Plasma cells [nTPM]":"1.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.3","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"38.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.8","Single Cell Type RNA - Spermatocytes [nTPM]":"12.4","Single Cell Type RNA - Spermatogonia [nTPM]":"2.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.1","Single Cell Type RNA - T-cells [nTPM]":"2.1","Single Cell Type RNA - Theca cells [nTPM]":"8.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.9","Single Cell Type RNA - Urothelial cells [nTPM]":"4.8"},{"Gene":"ABCA12","Gene synonym":["DKFZP434G232","ICR2B","LI2"],"Ensembl":"ENSG00000144452","Gene description":"ATP binding cassette subfamily A member 12","Uniprot":["Q86UK0"],"Chromosome":"2","Position":"214931542-215138626","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"breast":"5.7","skin 1":"20.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Basal keratinocytes":"12.9","Suprabasal keratinocytes":"38.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"5.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"hTCEpi":"38.7","SK-BR-3":"18.3","T-47d":"9.7"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"7","RNA pig brain regional specific nTPM":{"cerebral cortex":"1.0","hippocampal formation":"1.1"},"Antibody":["HPA078239"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 28: Keratinocytes - Keratinization","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Nucleoli","Cytosol"],"Antibody RRID":{"HPA078239":"AB_2732373"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"5.7","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"1.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.7","Tissue RNA - esophagus [nTPM]":"1.8","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"20.7","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"2.8","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"3.9","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"1.7","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"1.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"1.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"38.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"2.8","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.9","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"1.4","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"2.7","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"18.3","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"9.7","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"5.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"2.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.7","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.4","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"38.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.9","Single Cell Type RNA - Urothelial cells [nTPM]":"2.7"},{"Gene":"ABCA2","Gene synonym":["ABC2"],"Ensembl":"ENSG00000107331","Gene description":"ATP binding cassette subfamily A member 2","Uniprot":["Q9BZC7"],"Chromosome":"9","Position":"137007234-137028922","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"23","RNA tissue specific nTPM":{"brain":"543.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Oligodendrocytes":"388.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"T-47d":"66.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042886"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA042886":"AB_2678213"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.21e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.0","Tissue RNA - adrenal gland [nTPM]":"6.0","Tissue RNA - amygdala [nTPM]":"90.2","Tissue RNA - appendix [nTPM]":"4.2","Tissue RNA - basal ganglia [nTPM]":"269.7","Tissue RNA - bone marrow [nTPM]":"6.7","Tissue RNA - breast [nTPM]":"6.3","Tissue RNA - cerebellum [nTPM]":"194.3","Tissue RNA - cerebral cortex [nTPM]":"189.0","Tissue RNA - cervix [nTPM]":"5.9","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"7.9","Tissue RNA - duodenum [nTPM]":"3.0","Tissue RNA - endometrium 1 [nTPM]":"4.3","Tissue RNA - epididymis [nTPM]":"4.5","Tissue RNA - esophagus [nTPM]":"3.3","Tissue RNA - fallopian tube [nTPM]":"6.2","Tissue RNA - gallbladder [nTPM]":"5.9","Tissue RNA - heart muscle [nTPM]":"9.1","Tissue RNA - hippocampal formation [nTPM]":"92.4","Tissue RNA - hypothalamus [nTPM]":"101.3","Tissue RNA - kidney [nTPM]":"7.1","Tissue RNA - liver [nTPM]":"7.4","Tissue RNA - lung [nTPM]":"6.2","Tissue RNA - lymph node [nTPM]":"4.6","Tissue RNA - medulla oblongata [nTPM]":"284.9","Tissue RNA - midbrain [nTPM]":"211.4","Tissue RNA - ovary [nTPM]":"3.2","Tissue RNA - pancreas [nTPM]":"9.3","Tissue RNA - parathyroid gland [nTPM]":"13.4","Tissue RNA - pituitary gland [nTPM]":"23.4","Tissue RNA - placenta [nTPM]":"3.1","Tissue RNA - pons [nTPM]":"255.1","Tissue RNA - prostate [nTPM]":"7.1","Tissue RNA - rectum [nTPM]":"2.2","Tissue RNA - retina [nTPM]":"2.7","Tissue RNA - salivary gland [nTPM]":"8.4","Tissue RNA - seminal vesicle [nTPM]":"4.7","Tissue RNA - skeletal muscle [nTPM]":"7.3","Tissue RNA - skin 1 [nTPM]":"6.6","Tissue RNA - small intestine [nTPM]":"6.5","Tissue RNA - smooth muscle [nTPM]":"2.4","Tissue RNA - spinal cord [nTPM]":"135.7","Tissue RNA - spleen [nTPM]":"9.5","Tissue RNA - stomach 1 [nTPM]":"11.6","Tissue RNA - testis [nTPM]":"2.9","Tissue RNA - thalamus [nTPM]":"204.9","Tissue RNA - thymus [nTPM]":"2.9","Tissue RNA - thyroid gland [nTPM]":"15.2","Tissue RNA - tongue [nTPM]":"3.5","Tissue RNA - tonsil [nTPM]":"1.8","Tissue RNA - urinary bladder [nTPM]":"5.6","Tissue RNA - vagina [nTPM]":"5.3","Tissue RNA - white matter [nTPM]":"543.0","Cell RNA - A-431 [nTPM]":"8.6","Cell RNA - A549 [nTPM]":"9.2","Cell RNA - AF22 [nTPM]":"4.5","Cell RNA - AN3-CA [nTPM]":"18.2","Cell RNA - ASC diff [nTPM]":"11.1","Cell RNA - ASC TERT1 [nTPM]":"11.8","Cell RNA - BEWO [nTPM]":"7.9","Cell RNA - BJ [nTPM]":"9.5","Cell RNA - BJ hTERT+ [nTPM]":"3.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.5","Cell RNA - CACO-2 [nTPM]":"2.8","Cell RNA - CAPAN-2 [nTPM]":"10.3","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"26.2","Cell RNA - fHDF\/TERT166 [nTPM]":"10.2","Cell RNA - GAMG [nTPM]":"4.1","Cell RNA - HaCaT [nTPM]":"14.4","Cell RNA - HAP1 [nTPM]":"2.9","Cell RNA - HBEC3-KT [nTPM]":"6.9","Cell RNA - HBF TERT88 [nTPM]":"0.8","Cell RNA - HDLM-2 [nTPM]":"6.4","Cell RNA - HEK 293 [nTPM]":"5.9","Cell RNA - HEL [nTPM]":"0.8","Cell RNA - HeLa [nTPM]":"26.2","Cell RNA - Hep G2 [nTPM]":"3.5","Cell RNA - HHSteC [nTPM]":"5.5","Cell RNA - HL-60 [nTPM]":"13.3","Cell RNA - HMC-1 [nTPM]":"14.5","Cell RNA - HSkMC [nTPM]":"5.0","Cell RNA - hTCEpi [nTPM]":"6.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.0","Cell RNA - hTERT-HME1 [nTPM]":"0.9","Cell RNA - hTERT-RPE1 [nTPM]":"15.3","Cell RNA - HUVEC TERT2 [nTPM]":"2.4","Cell RNA - JURKAT [nTPM]":"2.7","Cell RNA - K-562 [nTPM]":"2.2","Cell RNA - Karpas-707 [nTPM]":"1.5","Cell RNA - LHCN-M2 [nTPM]":"5.3","Cell RNA - MCF7 [nTPM]":"25.7","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"29.1","Cell RNA - NTERA-2 [nTPM]":"2.4","Cell RNA - OE19 [nTPM]":"10.9","Cell RNA - PC-3 [nTPM]":"9.5","Cell RNA - REH [nTPM]":"13.3","Cell RNA - RH-30 [nTPM]":"4.6","Cell RNA - RPMI-8226 [nTPM]":"13.0","Cell RNA - RPTEC TERT1 [nTPM]":"2.9","Cell RNA - RT4 [nTPM]":"2.0","Cell RNA - SCLC-21H [nTPM]":"17.4","Cell RNA - SH-SY5Y [nTPM]":"20.0","Cell RNA - SiHa [nTPM]":"10.1","Cell RNA - SK-BR-3 [nTPM]":"19.6","Cell RNA - SK-MEL-30 [nTPM]":"7.2","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"66.4","Cell RNA - THP-1 [nTPM]":"17.4","Cell RNA - TIME [nTPM]":"11.9","Cell RNA - U-138 MG [nTPM]":"11.2","Cell RNA - U-2 OS [nTPM]":"6.1","Cell RNA - U-2197 [nTPM]":"16.0","Cell RNA - U-251 MG [nTPM]":"3.9","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"19.0","Cell RNA - U-937 [nTPM]":"2.6","Cell RNA - WM-115 [nTPM]":"5.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"90.2","Brain RNA - basal ganglia [nTPM]":"269.7","Brain RNA - cerebellum [nTPM]":"194.3","Brain RNA - cerebral cortex [nTPM]":"189.0","Brain RNA - hippocampal formation [nTPM]":"92.4","Brain RNA - hypothalamus [nTPM]":"101.3","Brain RNA - medulla oblongata [nTPM]":"284.9","Brain RNA - midbrain [nTPM]":"211.4","Brain RNA - pons [nTPM]":"255.1","Brain RNA - spinal cord [nTPM]":"135.7","Brain RNA - thalamus [nTPM]":"204.9","Brain RNA - white matter [nTPM]":"543.0","Single Cell Type RNA - Adipocytes [nTPM]":"7.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"26.1","Single Cell Type RNA - B-cells [nTPM]":"2.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"12.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"2.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - dendritic cells [nTPM]":"24.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.9","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.8","Single Cell Type RNA - Endothelial cells [nTPM]":"4.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"34.7","Single Cell Type RNA - Erythroid cells [nTPM]":"6.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.2","Single Cell Type RNA - Fibroblasts [nTPM]":"6.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"12.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"8.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.2","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.5","Single Cell Type RNA - Langerhans cells [nTPM]":"4.6","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"22.1","Single Cell Type RNA - Macrophages [nTPM]":"2.7","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"0.9","Single Cell Type RNA - Muller glia cells [nTPM]":"12.8","Single Cell Type RNA - NK-cells [nTPM]":"24.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"388.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.3","Single Cell Type RNA - Paneth cells [nTPM]":"7.1","Single Cell Type RNA - Peritubular cells [nTPM]":"23.7","Single Cell Type RNA - Plasma cells [nTPM]":"6.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"4.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"13.2","Single Cell Type RNA - Theca cells [nTPM]":"2.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"ABCA3","Gene synonym":["ABC-C","ABC3","EST111653","LBM180"],"Ensembl":"ENSG00000167972","Gene description":"ATP binding cassette subfamily A member 3","Uniprot":["Q99758"],"Chromosome":"16","Position":"2275881-2340746","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"91.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Alveolar cells type 2":"427.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"34.6","SCLC-21H":"45.9","T-47d":"76.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007884"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 11: Alveolar cells - Smell perception","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA007884":"AB_1078077"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.8","Tissue RNA - adrenal gland [nTPM]":"8.7","Tissue RNA - amygdala [nTPM]":"19.1","Tissue RNA - appendix [nTPM]":"3.0","Tissue RNA - basal ganglia [nTPM]":"20.8","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"6.7","Tissue RNA - cerebellum [nTPM]":"10.2","Tissue RNA - cerebral cortex [nTPM]":"25.5","Tissue RNA - cervix [nTPM]":"3.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"7.9","Tissue RNA - duodenum [nTPM]":"2.0","Tissue RNA - endometrium 1 [nTPM]":"3.7","Tissue RNA - epididymis [nTPM]":"3.5","Tissue RNA - esophagus [nTPM]":"2.9","Tissue RNA - fallopian tube [nTPM]":"4.4","Tissue RNA - gallbladder [nTPM]":"2.7","Tissue RNA - heart muscle [nTPM]":"6.1","Tissue RNA - hippocampal formation [nTPM]":"23.4","Tissue RNA - hypothalamus [nTPM]":"17.1","Tissue RNA - kidney [nTPM]":"6.5","Tissue RNA - liver [nTPM]":"1.1","Tissue RNA - lung [nTPM]":"91.2","Tissue RNA - lymph node [nTPM]":"3.7","Tissue RNA - medulla oblongata [nTPM]":"20.1","Tissue RNA - midbrain [nTPM]":"15.8","Tissue RNA - ovary [nTPM]":"3.4","Tissue RNA - pancreas [nTPM]":"13.1","Tissue RNA - parathyroid gland [nTPM]":"11.2","Tissue RNA - pituitary gland [nTPM]":"11.1","Tissue RNA - placenta [nTPM]":"4.3","Tissue RNA - pons [nTPM]":"22.2","Tissue RNA - prostate [nTPM]":"4.9","Tissue RNA - rectum [nTPM]":"1.2","Tissue RNA - retina [nTPM]":"7.4","Tissue RNA - salivary gland [nTPM]":"9.1","Tissue RNA - seminal vesicle [nTPM]":"4.3","Tissue RNA - skeletal muscle [nTPM]":"6.2","Tissue RNA - skin 1 [nTPM]":"4.3","Tissue RNA - small intestine [nTPM]":"3.9","Tissue RNA - smooth muscle [nTPM]":"4.6","Tissue RNA - spinal cord [nTPM]":"11.1","Tissue RNA - spleen [nTPM]":"3.4","Tissue RNA - stomach 1 [nTPM]":"4.9","Tissue RNA - testis [nTPM]":"8.9","Tissue RNA - thalamus [nTPM]":"19.1","Tissue RNA - thymus [nTPM]":"11.3","Tissue RNA - thyroid gland [nTPM]":"24.6","Tissue RNA - tongue [nTPM]":"3.8","Tissue RNA - tonsil [nTPM]":"6.5","Tissue RNA - urinary bladder [nTPM]":"4.5","Tissue RNA - vagina [nTPM]":"2.2","Tissue RNA - white matter [nTPM]":"19.7","Cell RNA - A-431 [nTPM]":"0.7","Cell RNA - A549 [nTPM]":"21.6","Cell RNA - AF22 [nTPM]":"4.1","Cell RNA - AN3-CA [nTPM]":"33.1","Cell RNA - ASC diff [nTPM]":"0.8","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"5.8","Cell RNA - BJ hTERT+ [nTPM]":"1.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.4","Cell RNA - CACO-2 [nTPM]":"3.0","Cell RNA - CAPAN-2 [nTPM]":"3.4","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"8.4","Cell RNA - fHDF\/TERT166 [nTPM]":"2.7","Cell RNA - GAMG [nTPM]":"2.1","Cell RNA - HaCaT [nTPM]":"0.6","Cell RNA - HAP1 [nTPM]":"19.2","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"0.8","Cell RNA - HDLM-2 [nTPM]":"34.6","Cell RNA - HEK 293 [nTPM]":"12.9","Cell RNA - HEL [nTPM]":"2.2","Cell RNA - HeLa [nTPM]":"2.5","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"2.9","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"3.6","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.3","Cell RNA - hTERT-HME1 [nTPM]":"1.1","Cell RNA - hTERT-RPE1 [nTPM]":"13.4","Cell RNA - HUVEC TERT2 [nTPM]":"32.4","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"24.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"29.3","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"2.4","Cell RNA - NTERA-2 [nTPM]":"4.4","Cell RNA - OE19 [nTPM]":"5.2","Cell RNA - PC-3 [nTPM]":"10.4","Cell RNA - REH [nTPM]":"5.4","Cell RNA - RH-30 [nTPM]":"0.7","Cell RNA - RPMI-8226 [nTPM]":"3.8","Cell RNA - RPTEC TERT1 [nTPM]":"18.7","Cell RNA - RT4 [nTPM]":"0.7","Cell RNA - SCLC-21H [nTPM]":"45.9","Cell RNA - SH-SY5Y [nTPM]":"33.0","Cell RNA - SiHa [nTPM]":"4.1","Cell RNA - SK-BR-3 [nTPM]":"23.4","Cell RNA - SK-MEL-30 [nTPM]":"0.6","Cell RNA - SuSa [nTPM]":"1.6","Cell RNA - T-47d [nTPM]":"76.5","Cell RNA - THP-1 [nTPM]":"2.0","Cell RNA - TIME [nTPM]":"9.3","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"1.1","Cell RNA - U-2197 [nTPM]":"9.0","Cell RNA - U-251 MG [nTPM]":"9.8","Cell RNA - U-266\/70 [nTPM]":"6.1","Cell RNA - U-266\/84 [nTPM]":"2.9","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"4.7","Cell RNA - U-937 [nTPM]":"11.7","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"19.1","Brain RNA - basal ganglia [nTPM]":"20.8","Brain RNA - cerebellum [nTPM]":"10.2","Brain RNA - cerebral cortex [nTPM]":"25.5","Brain RNA - hippocampal formation [nTPM]":"23.4","Brain RNA - hypothalamus [nTPM]":"17.1","Brain RNA - medulla oblongata [nTPM]":"20.1","Brain RNA - midbrain [nTPM]":"15.8","Brain RNA - pons [nTPM]":"22.2","Brain RNA - spinal cord [nTPM]":"11.1","Brain RNA - thalamus [nTPM]":"19.1","Brain RNA - white matter [nTPM]":"19.7","Single Cell Type RNA - Adipocytes [nTPM]":"4.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"70.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"427.4","Single Cell Type RNA - Astrocytes [nTPM]":"30.0","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"20.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"9.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"2.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.7","Single Cell Type RNA - Early spermatids [nTPM]":"7.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"6.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"60.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.9","Single Cell Type RNA - granulocytes [nTPM]":"29.7","Single Cell Type RNA - Granulosa cells [nTPM]":"7.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"0.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.0","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"58.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.8","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"1.2","Single Cell Type RNA - Langerhans cells [nTPM]":"1.8","Single Cell Type RNA - Late spermatids [nTPM]":"3.8","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"3.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"2.2","Single Cell Type RNA - Muller glia cells [nTPM]":"7.1","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"32.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"37.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.4","Single Cell Type RNA - Peritubular cells [nTPM]":"3.4","Single Cell Type RNA - Plasma cells [nTPM]":"3.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.9","Single Cell Type RNA - Spermatocytes [nTPM]":"5.1","Single Cell Type RNA - Spermatogonia [nTPM]":"15.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"3.9","Single Cell Type RNA - Theca cells [nTPM]":"1.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"ABCA4","Gene synonym":["ABCR","ARMD2","CORD3","FFM","RP19","STGD","STGD1"],"Ensembl":"ENSG00000198691","Gene description":"ATP binding cassette subfamily A member 4","Uniprot":["P78363"],"Chromosome":"1","Position":"93992834-94121148","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Sensory transduction","Transport","Vision"],"Molecular function":["Translocase"],"Disease involvement":["Age-related macular degeneration","Cone-rod dystrophy","Disease variant","Retinitis pigmentosa","Stargardt disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"32","RNA tissue specific nTPM":{"choroid plexus":"144.6","retina":"461.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"450.4","Rod photoreceptor cells":"482.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"lung cancer":"3.1"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"hippocampal formation":"9.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"3.1","EFO-21":"6.8","HeLa":"2.3","SK-BR-3":"3.0","SuSa":"3.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064420","HPA078826"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA064420":null,"HPA078826":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.45e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.72e-4"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.8","Tissue RNA - cerebellum [nTPM]":"1.1","Tissue RNA - cerebral cortex [nTPM]":"0.7","Tissue RNA - cervix [nTPM]":"0.5","Tissue RNA - choroid plexus [nTPM]":"144.6","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"2.5","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"8.4","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"9.3","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"8.7","Tissue RNA - liver [nTPM]":"0.9","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"0.5","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"461.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"1.4","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"2.1","Tissue RNA - small intestine [nTPM]":"2.9","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"1.4","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"3.1","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"6.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.3","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.7","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"2.3","Cell RNA - Hep G2 [nTPM]":"0.7","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.3","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.6","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.9","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.3","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.6","Cell RNA - SK-BR-3 [nTPM]":"3.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"3.1","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"1.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"1.1","Brain RNA - cerebral cortex [nTPM]":"0.7","Brain RNA - hippocampal formation [nTPM]":"9.3","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"0.5","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"1.4","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"1.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"27.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"450.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"8.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"3.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.5","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"21.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"37.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"482.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"ABCA7","Gene synonym":["ABCX"],"Ensembl":"ENSG00000064687","Gene description":"ATP binding cassette subfamily A member 7","Uniprot":["Q8IZY2"],"Chromosome":"19","Position":"1039997-1065572","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Phagocytosis","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Alzheimer disease","Amyloidosis","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"27.4","pituitary gland":"28.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"73.7","Bipolar cells":"70.6","Cone photoreceptor cells":"175.2","Extravillous trophoblasts":"303.3","Rod photoreceptor cells":"149.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"20.4","HMC-1":"40.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041564"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":["Golgi apparatus","Plasma membrane"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA041564":"AB_2677550"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.26e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.12e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.4","Tissue RNA - adrenal gland [nTPM]":"3.0","Tissue RNA - amygdala [nTPM]":"3.4","Tissue RNA - appendix [nTPM]":"5.5","Tissue RNA - basal ganglia [nTPM]":"3.9","Tissue RNA - bone marrow [nTPM]":"27.4","Tissue RNA - breast [nTPM]":"3.3","Tissue RNA - cerebellum [nTPM]":"4.0","Tissue RNA - cerebral cortex [nTPM]":"6.1","Tissue RNA - cervix [nTPM]":"3.2","Tissue RNA - choroid plexus [nTPM]":"11.5","Tissue RNA - colon [nTPM]":"3.8","Tissue RNA - duodenum [nTPM]":"2.3","Tissue RNA - endometrium 1 [nTPM]":"1.2","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"7.6","Tissue RNA - fallopian tube [nTPM]":"2.1","Tissue RNA - gallbladder [nTPM]":"2.1","Tissue RNA - heart muscle [nTPM]":"3.1","Tissue RNA - hippocampal formation [nTPM]":"3.6","Tissue RNA - hypothalamus [nTPM]":"3.7","Tissue RNA - kidney [nTPM]":"6.4","Tissue RNA - liver [nTPM]":"4.2","Tissue RNA - lung [nTPM]":"9.5","Tissue RNA - lymph node [nTPM]":"8.5","Tissue RNA - medulla oblongata [nTPM]":"5.8","Tissue RNA - midbrain [nTPM]":"4.5","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"7.7","Tissue RNA - parathyroid gland [nTPM]":"2.7","Tissue RNA - pituitary gland [nTPM]":"28.7","Tissue RNA - placenta [nTPM]":"1.2","Tissue RNA - pons [nTPM]":"5.3","Tissue RNA - prostate [nTPM]":"5.3","Tissue RNA - rectum [nTPM]":"1.2","Tissue RNA - retina [nTPM]":"25.5","Tissue RNA - salivary gland [nTPM]":"8.6","Tissue RNA - seminal vesicle [nTPM]":"1.1","Tissue RNA - skeletal muscle [nTPM]":"3.8","Tissue RNA - skin 1 [nTPM]":"5.9","Tissue RNA - small intestine [nTPM]":"10.1","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"3.0","Tissue RNA - spleen [nTPM]":"26.6","Tissue RNA - stomach 1 [nTPM]":"3.8","Tissue RNA - testis [nTPM]":"1.7","Tissue RNA - thalamus [nTPM]":"4.1","Tissue RNA - thymus [nTPM]":"10.0","Tissue RNA - thyroid gland [nTPM]":"5.7","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"3.2","Tissue RNA - urinary bladder [nTPM]":"2.3","Tissue RNA - vagina [nTPM]":"2.8","Tissue RNA - white matter [nTPM]":"3.2","Cell RNA - A-431 [nTPM]":"4.7","Cell RNA - A549 [nTPM]":"6.4","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"4.4","Cell RNA - ASC diff [nTPM]":"7.2","Cell RNA - ASC TERT1 [nTPM]":"2.2","Cell RNA - BEWO [nTPM]":"7.3","Cell RNA - BJ [nTPM]":"0.8","Cell RNA - BJ hTERT+ [nTPM]":"1.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.6","Cell RNA - CACO-2 [nTPM]":"5.2","Cell RNA - CAPAN-2 [nTPM]":"2.8","Cell RNA - Daudi [nTPM]":"13.9","Cell RNA - EFO-21 [nTPM]":"5.6","Cell RNA - fHDF\/TERT166 [nTPM]":"1.3","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"8.0","Cell RNA - HAP1 [nTPM]":"1.3","Cell RNA - HBEC3-KT [nTPM]":"6.2","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"10.2","Cell RNA - HEK 293 [nTPM]":"2.5","Cell RNA - HEL [nTPM]":"6.7","Cell RNA - HeLa [nTPM]":"20.4","Cell RNA - Hep G2 [nTPM]":"5.6","Cell RNA - HHSteC [nTPM]":"1.8","Cell RNA - HL-60 [nTPM]":"3.9","Cell RNA - HMC-1 [nTPM]":"40.3","Cell RNA - HSkMC [nTPM]":"3.8","Cell RNA - hTCEpi [nTPM]":"1.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.9","Cell RNA - hTERT-HME1 [nTPM]":"1.2","Cell RNA - hTERT-RPE1 [nTPM]":"4.4","Cell RNA - HUVEC TERT2 [nTPM]":"1.4","Cell RNA - JURKAT [nTPM]":"7.7","Cell RNA - K-562 [nTPM]":"10.2","Cell RNA - Karpas-707 [nTPM]":"6.9","Cell RNA - LHCN-M2 [nTPM]":"1.3","Cell RNA - MCF7 [nTPM]":"2.2","Cell RNA - MOLT-4 [nTPM]":"4.3","Cell RNA - NB-4 [nTPM]":"2.2","Cell RNA - NTERA-2 [nTPM]":"0.9","Cell RNA - OE19 [nTPM]":"3.3","Cell RNA - PC-3 [nTPM]":"2.5","Cell RNA - REH [nTPM]":"3.1","Cell RNA - RH-30 [nTPM]":"0.8","Cell RNA - RPMI-8226 [nTPM]":"11.6","Cell RNA - RPTEC TERT1 [nTPM]":"3.8","Cell RNA - RT4 [nTPM]":"6.0","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"1.3","Cell RNA - SiHa [nTPM]":"8.2","Cell RNA - SK-BR-3 [nTPM]":"1.9","Cell RNA - SK-MEL-30 [nTPM]":"1.2","Cell RNA - SuSa [nTPM]":"1.1","Cell RNA - T-47d [nTPM]":"4.6","Cell RNA - THP-1 [nTPM]":"7.1","Cell RNA - TIME [nTPM]":"2.2","Cell RNA - U-138 MG [nTPM]":"0.4","Cell RNA - U-2 OS [nTPM]":"1.6","Cell RNA - U-2197 [nTPM]":"3.7","Cell RNA - U-251 MG [nTPM]":"0.8","Cell RNA - U-266\/70 [nTPM]":"9.9","Cell RNA - U-266\/84 [nTPM]":"6.6","Cell RNA - U-698 [nTPM]":"5.7","Cell RNA - U-87 MG [nTPM]":"2.1","Cell RNA - U-937 [nTPM]":"7.4","Cell RNA - WM-115 [nTPM]":"2.0","Blood RNA - basophil [nTPM]":"2.8","Blood RNA - classical monocyte [nTPM]":"1.4","Blood RNA - eosinophil [nTPM]":"5.9","Blood RNA - gdT-cell [nTPM]":"1.8","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"1.1","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.2","Blood RNA - myeloid DC [nTPM]":"2.1","Blood RNA - naive B-cell [nTPM]":"0.9","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"3.3","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"7.3","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"1.3","Brain RNA - amygdala [nTPM]":"3.4","Brain RNA - basal ganglia [nTPM]":"3.9","Brain RNA - cerebellum [nTPM]":"4.0","Brain RNA - cerebral cortex [nTPM]":"6.1","Brain RNA - hippocampal formation [nTPM]":"3.6","Brain RNA - hypothalamus [nTPM]":"3.7","Brain RNA - medulla oblongata [nTPM]":"5.8","Brain RNA - midbrain [nTPM]":"4.5","Brain RNA - pons [nTPM]":"5.3","Brain RNA - spinal cord [nTPM]":"3.0","Brain RNA - thalamus [nTPM]":"4.1","Brain RNA - white matter [nTPM]":"3.2","Single Cell Type RNA - Adipocytes [nTPM]":"4.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"73.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.9","Single Cell Type RNA - Astrocytes [nTPM]":"8.5","Single Cell Type RNA - B-cells [nTPM]":"13.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"70.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"14.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"175.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.6","Single Cell Type RNA - dendritic cells [nTPM]":"9.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.7","Single Cell Type RNA - Early spermatids [nTPM]":"7.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.4","Single Cell Type RNA - Endothelial cells [nTPM]":"2.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.5","Single Cell Type RNA - Erythroid cells [nTPM]":"13.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"303.3","Single Cell Type RNA - Fibroblasts [nTPM]":"1.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.9","Single Cell Type RNA - granulocytes [nTPM]":"10.1","Single Cell Type RNA - Granulosa cells [nTPM]":"2.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"4.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.9","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.7","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"12.6","Single Cell Type RNA - Langerhans cells [nTPM]":"7.5","Single Cell Type RNA - Late spermatids [nTPM]":"4.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"12.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"19.6","Single Cell Type RNA - Muller glia cells [nTPM]":"13.1","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.0","Single Cell Type RNA - Paneth cells [nTPM]":"9.6","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"12.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"149.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"2.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"25.7","Single Cell Type RNA - T-cells [nTPM]":"12.6","Single Cell Type RNA - Theca cells [nTPM]":"1.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.3","Single Cell Type RNA - Urothelial cells [nTPM]":"1.9"},{"Gene":"ABCB11","Gene synonym":["ABC16","BSEP","PFIC-2","PFIC2","PGY4","SPGP"],"Ensembl":"ENSG00000073734","Gene description":"ATP binding cassette subfamily B member 11","Uniprot":["O95342"],"Chromosome":"2","Position":"168915498-169031324","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Intrahepatic cholestasis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"liver":"80.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"41.7","Alveolar cells type 2":"44.1","Club cells":"19.3","Early spermatids":"16.5","granulocytes":"24.0","Hepatocytes":"20.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"87","RNA cancer specific FPKM":{"liver cancer":"6.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"NB-4":"1.6","RT4":"1.6","TIME":"1.1"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019035"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 11: Alveolar cells - Smell perception","Subcellular main location":["Nucleoplasm","Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA019035":"AB_1844429"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.5","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.6","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"1.6","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"80.8","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"1.0","Tissue RNA - midbrain [nTPM]":"0.6","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.5","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"1.1","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"6.2","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"1.1","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"1.6","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"1.6","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.6","Cell RNA - TIME [nTPM]":"1.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.7","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"1.0","Brain RNA - midbrain [nTPM]":"0.6","Brain RNA - pons [nTPM]":"0.5","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"44.1","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"19.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"16.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"6.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"24.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"20.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"9.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"3.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"2.6","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"ABCB4","Gene synonym":["GBD1","MDR2","MDR3","PFIC-3","PGY3"],"Ensembl":"ENSG00000005471","Gene description":"ATP binding cassette subfamily B member 4","Uniprot":["P21439"],"Chromosome":"7","Position":"87401696-87480435","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Intrahepatic cholestasis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"16","RNA tissue specific nTPM":{"liver":"123.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Hepatocytes":"256.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"liver cancer":"16.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"memory B-cell":"4.4","naive B-cell":"8.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"B-cells":"8.1"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"SH-SY5Y":"12.9","WM-115":"25.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049395","HPA053288"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Actin filaments","Focal adhesion sites"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Nucleoplasm","Plasma membrane","Actin filaments"],"Subcellular additional location":["Focal adhesion sites"],"Antibody RRID":{"HPA049395":"AB_2680745","HPA053288":"AB_2682102"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.7","Tissue RNA - adrenal gland [nTPM]":"7.4","Tissue RNA - amygdala [nTPM]":"0.8","Tissue RNA - appendix [nTPM]":"2.5","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"0.9","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.4","Tissue RNA - colon [nTPM]":"1.1","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"0.6","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"6.6","Tissue RNA - hippocampal formation [nTPM]":"0.8","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"123.2","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"5.9","Tissue RNA - medulla oblongata [nTPM]":"0.9","Tissue RNA - midbrain [nTPM]":"0.6","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"1.0","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"1.2","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"0.6","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"7.5","Tissue RNA - skin 1 [nTPM]":"1.4","Tissue RNA - small intestine [nTPM]":"2.1","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"5.0","Tissue RNA - stomach 1 [nTPM]":"0.6","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"0.7","Tissue RNA - thymus [nTPM]":"0.7","Tissue RNA - thyroid gland [nTPM]":"0.5","Tissue RNA - tongue [nTPM]":"4.8","Tissue RNA - tonsil [nTPM]":"5.2","Tissue RNA - urinary bladder [nTPM]":"1.2","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"0.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"3.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"2.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"2.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"4.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"12.9","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"2.6","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.6","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"1.7","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"3.2","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"25.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"4.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"1.2","Blood RNA - naive B-cell [nTPM]":"8.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"0.8","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"0.9","Brain RNA - hippocampal formation [nTPM]":"0.8","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"0.9","Brain RNA - midbrain [nTPM]":"0.6","Brain RNA - pons [nTPM]":"1.0","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"0.7","Brain RNA - white matter [nTPM]":"0.7","Single Cell Type RNA - Adipocytes [nTPM]":"1.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"22.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"2.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"256.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.5","Single Cell Type RNA - Horizontal cells [nTPM]":"38.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"5.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"1.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.7","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"ABCB6","Gene synonym":["EST45597","MTABC3","umat"],"Ensembl":"ENSG00000115657","Gene description":"ATP binding cassette subfamily B member 6 (Langereis blood group)","Uniprot":["Q9NP58"],"Chromosome":"2","Position":"219209772-219218994","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Dyskeratosis congenita","Microphthalmia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"14.7","Excitatory neurons":"12.9","Gastric mucus-secreting cells":"5.1","Inhibitory neurons":"10.9","Oligodendrocyte precursor cells":"13.6","Oligodendrocytes":"5.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"65.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046723","HPA058011"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Plasma membrane","Mitochondria","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Plasma membrane","Mitochondria","Cytosol"],"Antibody RRID":{"HPA046723":"AB_10960288","HPA058011":"AB_2683578"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.45e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.52e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.2","Tissue RNA - adrenal gland [nTPM]":"8.7","Tissue RNA - amygdala [nTPM]":"4.3","Tissue RNA - appendix [nTPM]":"3.4","Tissue RNA - basal ganglia [nTPM]":"3.9","Tissue RNA - bone marrow [nTPM]":"10.4","Tissue RNA - breast [nTPM]":"7.6","Tissue RNA - cerebellum [nTPM]":"3.2","Tissue RNA - cerebral cortex [nTPM]":"4.6","Tissue RNA - cervix [nTPM]":"7.7","Tissue RNA - choroid plexus [nTPM]":"4.4","Tissue RNA - colon [nTPM]":"6.5","Tissue RNA - duodenum [nTPM]":"6.9","Tissue RNA - endometrium 1 [nTPM]":"8.4","Tissue RNA - epididymis [nTPM]":"8.2","Tissue RNA - esophagus [nTPM]":"11.4","Tissue RNA - fallopian tube [nTPM]":"9.6","Tissue RNA - gallbladder [nTPM]":"7.1","Tissue RNA - heart muscle [nTPM]":"8.5","Tissue RNA - hippocampal formation [nTPM]":"4.0","Tissue RNA - hypothalamus [nTPM]":"5.1","Tissue RNA - kidney [nTPM]":"5.2","Tissue RNA - liver [nTPM]":"15.9","Tissue RNA - lung [nTPM]":"5.9","Tissue RNA - lymph node [nTPM]":"1.9","Tissue RNA - medulla oblongata [nTPM]":"4.4","Tissue RNA - midbrain [nTPM]":"4.2","Tissue RNA - ovary [nTPM]":"12.9","Tissue RNA - pancreas [nTPM]":"5.7","Tissue RNA - parathyroid gland [nTPM]":"4.8","Tissue RNA - pituitary gland [nTPM]":"6.0","Tissue RNA - placenta [nTPM]":"3.1","Tissue RNA - pons [nTPM]":"6.2","Tissue RNA - prostate [nTPM]":"8.0","Tissue RNA - rectum [nTPM]":"3.3","Tissue RNA - retina [nTPM]":"3.0","Tissue RNA - salivary gland [nTPM]":"6.2","Tissue RNA - seminal vesicle [nTPM]":"8.6","Tissue RNA - skeletal muscle [nTPM]":"30.4","Tissue RNA - skin 1 [nTPM]":"6.8","Tissue RNA - small intestine [nTPM]":"6.3","Tissue RNA - smooth muscle [nTPM]":"7.9","Tissue RNA - spinal cord [nTPM]":"4.1","Tissue RNA - spleen [nTPM]":"3.9","Tissue RNA - stomach 1 [nTPM]":"7.9","Tissue RNA - testis [nTPM]":"18.0","Tissue RNA - thalamus [nTPM]":"5.7","Tissue RNA - thymus [nTPM]":"2.6","Tissue RNA - thyroid gland [nTPM]":"10.7","Tissue RNA - tongue [nTPM]":"9.8","Tissue RNA - tonsil [nTPM]":"2.9","Tissue RNA - urinary bladder [nTPM]":"14.9","Tissue RNA - vagina [nTPM]":"7.9","Tissue RNA - white matter [nTPM]":"5.0","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"22.9","Cell RNA - AF22 [nTPM]":"4.7","Cell RNA - AN3-CA [nTPM]":"28.8","Cell RNA - ASC diff [nTPM]":"30.8","Cell RNA - ASC TERT1 [nTPM]":"11.1","Cell RNA - BEWO [nTPM]":"27.6","Cell RNA - BJ [nTPM]":"8.5","Cell RNA - BJ hTERT+ [nTPM]":"7.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.2","Cell RNA - CACO-2 [nTPM]":"35.5","Cell RNA - CAPAN-2 [nTPM]":"5.0","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"42.8","Cell RNA - fHDF\/TERT166 [nTPM]":"8.6","Cell RNA - GAMG [nTPM]":"5.0","Cell RNA - HaCaT [nTPM]":"49.1","Cell RNA - HAP1 [nTPM]":"0.6","Cell RNA - HBEC3-KT [nTPM]":"3.6","Cell RNA - HBF TERT88 [nTPM]":"3.0","Cell RNA - HDLM-2 [nTPM]":"15.0","Cell RNA - HEK 293 [nTPM]":"4.7","Cell RNA - HEL [nTPM]":"36.3","Cell RNA - HeLa [nTPM]":"24.9","Cell RNA - Hep G2 [nTPM]":"65.8","Cell RNA - HHSteC [nTPM]":"37.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"12.0","Cell RNA - HSkMC [nTPM]":"16.3","Cell RNA - hTCEpi [nTPM]":"4.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.2","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"13.9","Cell RNA - HUVEC TERT2 [nTPM]":"16.3","Cell RNA - JURKAT [nTPM]":"4.8","Cell RNA - K-562 [nTPM]":"31.4","Cell RNA - Karpas-707 [nTPM]":"4.4","Cell RNA - LHCN-M2 [nTPM]":"6.3","Cell RNA - MCF7 [nTPM]":"12.0","Cell RNA - MOLT-4 [nTPM]":"2.3","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"7.2","Cell RNA - OE19 [nTPM]":"53.6","Cell RNA - PC-3 [nTPM]":"9.2","Cell RNA - REH [nTPM]":"12.3","Cell RNA - RH-30 [nTPM]":"14.3","Cell RNA - RPMI-8226 [nTPM]":"1.6","Cell RNA - RPTEC TERT1 [nTPM]":"5.1","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"16.6","Cell RNA - SH-SY5Y [nTPM]":"17.8","Cell RNA - SiHa [nTPM]":"17.6","Cell RNA - SK-BR-3 [nTPM]":"41.4","Cell RNA - SK-MEL-30 [nTPM]":"18.7","Cell RNA - SuSa [nTPM]":"17.4","Cell RNA - T-47d [nTPM]":"12.4","Cell RNA - THP-1 [nTPM]":"0.8","Cell RNA - TIME [nTPM]":"7.5","Cell RNA - U-138 MG [nTPM]":"12.5","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"16.9","Cell RNA - U-251 MG [nTPM]":"10.3","Cell RNA - U-266\/70 [nTPM]":"11.2","Cell RNA - U-266\/84 [nTPM]":"9.6","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"14.0","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"17.0","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"1.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.8","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.8","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"2.3","Blood RNA - T-reg [nTPM]":"0.5","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"4.3","Brain RNA - basal ganglia [nTPM]":"3.9","Brain RNA - cerebellum [nTPM]":"3.2","Brain RNA - cerebral cortex [nTPM]":"4.6","Brain RNA - hippocampal formation [nTPM]":"4.0","Brain RNA - hypothalamus [nTPM]":"5.1","Brain RNA - medulla oblongata [nTPM]":"4.4","Brain RNA - midbrain [nTPM]":"4.2","Brain RNA - pons [nTPM]":"6.2","Brain RNA - spinal cord [nTPM]":"4.1","Brain RNA - thalamus [nTPM]":"5.7","Brain RNA - white matter [nTPM]":"5.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"1.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"ABCB7","Gene synonym":["ABC7","ASAT","Atm1p","EST140535"],"Ensembl":"ENSG00000131269","Gene description":"ATP binding cassette subfamily B member 7","Uniprot":["O75027"],"Chromosome":"X","Position":"75051048-75156732","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034982"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA034982":"AB_10601010"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.31e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Tissue RNA - adipose tissue [nTPM]":"12.6","Tissue RNA - adrenal gland [nTPM]":"13.5","Tissue RNA - amygdala [nTPM]":"5.0","Tissue RNA - appendix [nTPM]":"7.7","Tissue RNA - basal ganglia [nTPM]":"5.9","Tissue RNA - bone marrow [nTPM]":"11.1","Tissue RNA - breast [nTPM]":"11.8","Tissue RNA - cerebellum [nTPM]":"8.2","Tissue RNA - cerebral cortex [nTPM]":"7.6","Tissue RNA - cervix [nTPM]":"11.4","Tissue RNA - choroid plexus [nTPM]":"9.8","Tissue RNA - colon [nTPM]":"13.8","Tissue RNA - duodenum [nTPM]":"16.0","Tissue RNA - endometrium 1 [nTPM]":"10.9","Tissue RNA - epididymis [nTPM]":"5.0","Tissue RNA - esophagus [nTPM]":"11.6","Tissue RNA - fallopian tube [nTPM]":"11.2","Tissue RNA - gallbladder [nTPM]":"7.4","Tissue RNA - heart muscle [nTPM]":"22.0","Tissue RNA - hippocampal formation [nTPM]":"5.5","Tissue RNA - hypothalamus [nTPM]":"6.1","Tissue RNA - kidney [nTPM]":"10.1","Tissue RNA - liver [nTPM]":"14.8","Tissue RNA - lung [nTPM]":"9.8","Tissue RNA - lymph node [nTPM]":"12.0","Tissue RNA - medulla oblongata [nTPM]":"6.4","Tissue RNA - midbrain [nTPM]":"6.0","Tissue RNA - ovary [nTPM]":"12.3","Tissue RNA - pancreas [nTPM]":"9.6","Tissue RNA - parathyroid gland [nTPM]":"11.0","Tissue RNA - pituitary gland [nTPM]":"8.6","Tissue RNA - placenta [nTPM]":"7.5","Tissue RNA - pons [nTPM]":"6.2","Tissue RNA - prostate [nTPM]":"8.5","Tissue RNA - rectum [nTPM]":"9.6","Tissue RNA - retina [nTPM]":"9.8","Tissue RNA - salivary gland [nTPM]":"10.0","Tissue RNA - seminal vesicle [nTPM]":"6.9","Tissue RNA - skeletal muscle [nTPM]":"31.4","Tissue RNA - skin 1 [nTPM]":"12.9","Tissue RNA - small intestine [nTPM]":"11.8","Tissue RNA - smooth muscle [nTPM]":"8.8","Tissue RNA - spinal cord [nTPM]":"6.1","Tissue RNA - spleen [nTPM]":"10.9","Tissue RNA - stomach 1 [nTPM]":"12.3","Tissue RNA - testis [nTPM]":"4.1","Tissue RNA - thalamus [nTPM]":"5.4","Tissue RNA - thymus [nTPM]":"14.0","Tissue RNA - thyroid gland [nTPM]":"9.5","Tissue RNA - tongue [nTPM]":"22.2","Tissue RNA - tonsil [nTPM]":"11.1","Tissue RNA - urinary bladder [nTPM]":"10.5","Tissue RNA - vagina [nTPM]":"10.9","Tissue RNA - white matter [nTPM]":"6.8","Cell RNA - A-431 [nTPM]":"17.0","Cell RNA - A549 [nTPM]":"16.2","Cell RNA - AF22 [nTPM]":"12.2","Cell RNA - AN3-CA [nTPM]":"20.9","Cell RNA - ASC diff [nTPM]":"14.1","Cell RNA - ASC TERT1 [nTPM]":"25.5","Cell RNA - BEWO [nTPM]":"7.0","Cell RNA - BJ [nTPM]":"8.9","Cell RNA - BJ hTERT+ [nTPM]":"14.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"22.4","Cell RNA - CACO-2 [nTPM]":"18.5","Cell RNA - CAPAN-2 [nTPM]":"24.5","Cell RNA - Daudi [nTPM]":"25.8","Cell RNA - EFO-21 [nTPM]":"22.8","Cell RNA - fHDF\/TERT166 [nTPM]":"9.2","Cell RNA - GAMG [nTPM]":"21.2","Cell RNA - HaCaT [nTPM]":"18.8","Cell RNA - HAP1 [nTPM]":"25.6","Cell RNA - HBEC3-KT [nTPM]":"18.5","Cell RNA - HBF TERT88 [nTPM]":"12.0","Cell RNA - HDLM-2 [nTPM]":"26.0","Cell RNA - HEK 293 [nTPM]":"33.2","Cell RNA - HEL [nTPM]":"16.8","Cell RNA - HeLa [nTPM]":"29.2","Cell RNA - Hep G2 [nTPM]":"17.3","Cell RNA - HHSteC [nTPM]":"8.2","Cell RNA - HL-60 [nTPM]":"24.7","Cell RNA - HMC-1 [nTPM]":"13.7","Cell RNA - HSkMC [nTPM]":"15.9","Cell RNA - hTCEpi [nTPM]":"16.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.8","Cell RNA - hTERT-HME1 [nTPM]":"16.7","Cell RNA - hTERT-RPE1 [nTPM]":"21.3","Cell RNA - HUVEC TERT2 [nTPM]":"23.1","Cell RNA - JURKAT [nTPM]":"26.2","Cell RNA - K-562 [nTPM]":"18.9","Cell RNA - Karpas-707 [nTPM]":"31.1","Cell RNA - LHCN-M2 [nTPM]":"9.8","Cell RNA - MCF7 [nTPM]":"10.5","Cell RNA - MOLT-4 [nTPM]":"24.4","Cell RNA - NB-4 [nTPM]":"26.1","Cell RNA - NTERA-2 [nTPM]":"26.8","Cell RNA - OE19 [nTPM]":"26.3","Cell RNA - PC-3 [nTPM]":"30.5","Cell RNA - REH [nTPM]":"21.4","Cell RNA - RH-30 [nTPM]":"26.9","Cell RNA - RPMI-8226 [nTPM]":"30.5","Cell RNA - RPTEC TERT1 [nTPM]":"12.7","Cell RNA - RT4 [nTPM]":"13.2","Cell RNA - SCLC-21H [nTPM]":"17.7","Cell RNA - SH-SY5Y [nTPM]":"14.1","Cell RNA - SiHa [nTPM]":"27.4","Cell RNA - SK-BR-3 [nTPM]":"23.5","Cell RNA - SK-MEL-30 [nTPM]":"17.8","Cell RNA - SuSa [nTPM]":"20.0","Cell RNA - T-47d [nTPM]":"10.2","Cell RNA - THP-1 [nTPM]":"22.9","Cell RNA - TIME [nTPM]":"10.3","Cell RNA - U-138 MG [nTPM]":"11.3","Cell RNA - U-2 OS [nTPM]":"22.9","Cell RNA - U-2197 [nTPM]":"23.2","Cell RNA - U-251 MG [nTPM]":"12.4","Cell RNA - U-266\/70 [nTPM]":"10.1","Cell RNA - U-266\/84 [nTPM]":"27.5","Cell RNA - U-698 [nTPM]":"21.2","Cell RNA - U-87 MG [nTPM]":"10.1","Cell RNA - U-937 [nTPM]":"35.8","Cell RNA - WM-115 [nTPM]":"9.4","Blood RNA - basophil [nTPM]":"9.6","Blood RNA - classical monocyte [nTPM]":"26.9","Blood RNA - eosinophil [nTPM]":"10.0","Blood RNA - gdT-cell [nTPM]":"15.7","Blood RNA - intermediate monocyte [nTPM]":"25.6","Blood RNA - MAIT T-cell [nTPM]":"16.6","Blood RNA - memory B-cell [nTPM]":"24.7","Blood RNA - memory CD4 T-cell [nTPM]":"16.7","Blood RNA - memory CD8 T-cell [nTPM]":"16.7","Blood RNA - myeloid DC [nTPM]":"29.0","Blood RNA - naive B-cell [nTPM]":"28.2","Blood RNA - naive CD4 T-cell [nTPM]":"28.7","Blood RNA - naive CD8 T-cell [nTPM]":"21.1","Blood RNA - neutrophil [nTPM]":"2.4","Blood RNA - NK-cell [nTPM]":"17.5","Blood RNA - non-classical monocyte [nTPM]":"20.4","Blood RNA - plasmacytoid DC [nTPM]":"18.2","Blood RNA - T-reg [nTPM]":"27.2","Blood RNA - total PBMC [nTPM]":"19.2","Brain RNA - amygdala [nTPM]":"5.0","Brain RNA - basal ganglia [nTPM]":"5.9","Brain RNA - cerebellum [nTPM]":"8.2","Brain RNA - cerebral cortex [nTPM]":"7.6","Brain RNA - hippocampal formation [nTPM]":"5.5","Brain RNA - hypothalamus [nTPM]":"6.1","Brain RNA - medulla oblongata [nTPM]":"6.4","Brain RNA - midbrain [nTPM]":"6.0","Brain RNA - pons [nTPM]":"6.2","Brain RNA - spinal cord [nTPM]":"6.1","Brain RNA - thalamus [nTPM]":"5.4","Brain RNA - white matter [nTPM]":"6.8","Single Cell Type RNA - Adipocytes [nTPM]":"12.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.4","Single Cell Type RNA - Astrocytes [nTPM]":"48.0","Single Cell Type RNA - B-cells [nTPM]":"26.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.9","Single Cell Type RNA - Bipolar cells [nTPM]":"10.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"46.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"14.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.0","Single Cell Type RNA - dendritic cells [nTPM]":"19.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"17.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.8","Single Cell Type RNA - Endothelial cells [nTPM]":"11.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.8","Single Cell Type RNA - Erythroid cells [nTPM]":"26.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"37.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.6","Single Cell Type RNA - Fibroblasts [nTPM]":"13.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.1","Single Cell Type RNA - granulocytes [nTPM]":"22.2","Single Cell Type RNA - Granulosa cells [nTPM]":"20.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.3","Single Cell Type RNA - Hepatocytes [nTPM]":"11.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.1","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"39.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.5","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"26.1","Single Cell Type RNA - Langerhans cells [nTPM]":"16.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"14.6","Single Cell Type RNA - Macrophages [nTPM]":"19.2","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"45.0","Single Cell Type RNA - monocytes [nTPM]":"22.9","Single Cell Type RNA - Muller glia cells [nTPM]":"12.4","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"43.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"46.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.6","Single Cell Type RNA - Paneth cells [nTPM]":"7.9","Single Cell Type RNA - Peritubular cells [nTPM]":"13.2","Single Cell Type RNA - Plasma cells [nTPM]":"14.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.9","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.8","Single Cell Type RNA - Spermatocytes [nTPM]":"5.5","Single Cell Type RNA - Spermatogonia [nTPM]":"10.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.3","Single Cell Type RNA - T-cells [nTPM]":"14.5","Single Cell Type RNA - Theca cells [nTPM]":"19.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.9","Single Cell Type RNA - Urothelial cells [nTPM]":"11.9"},{"Gene":"ABCC6","Gene synonym":["ARA","EST349056","MLP1","MRP6","PXE","URG7"],"Ensembl":"ENSG00000091262","Gene description":"ATP binding cassette subfamily C member 6","Uniprot":["O95255"],"Chromosome":"16","Position":"16149565-16223522","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Sensory transduction","Transport","Vision"],"Molecular function":["Translocase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"liver":"134.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"31.5","Distal tubular cells":"45.0","Hepatocytes":"77.9","Proximal enterocytes":"33.7","Proximal tubular cells":"151.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"liver cancer":"16.7","renal cancer":"5.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"classical monocyte":"3.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"monocytes":"3.4"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Hep G2":"68.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038105"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA038105":"AB_2675835"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.82e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.6","Tissue RNA - adrenal gland [nTPM]":"3.6","Tissue RNA - amygdala [nTPM]":"0.7","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"0.7","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"3.8","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"1.1","Tissue RNA - cervix [nTPM]":"1.0","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"5.7","Tissue RNA - duodenum [nTPM]":"13.2","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"1.5","Tissue RNA - gallbladder [nTPM]":"2.9","Tissue RNA - heart muscle [nTPM]":"2.6","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"0.7","Tissue RNA - kidney [nTPM]":"27.4","Tissue RNA - liver [nTPM]":"134.2","Tissue RNA - lung [nTPM]":"7.4","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.8","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"1.0","Tissue RNA - pancreas [nTPM]":"17.2","Tissue RNA - parathyroid gland [nTPM]":"2.1","Tissue RNA - pituitary gland [nTPM]":"0.9","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"0.8","Tissue RNA - prostate [nTPM]":"2.9","Tissue RNA - rectum [nTPM]":"2.8","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"12.7","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"4.6","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"7.9","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.7","Tissue RNA - spleen [nTPM]":"0.7","Tissue RNA - stomach 1 [nTPM]":"6.4","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"0.8","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"5.6","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"0.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"1.5","Cell RNA - AF22 [nTPM]":"0.7","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.8","Cell RNA - BEWO [nTPM]":"1.8","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.6","Cell RNA - CACO-2 [nTPM]":"7.1","Cell RNA - CAPAN-2 [nTPM]":"2.3","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.7","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.6","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.7","Cell RNA - HEL [nTPM]":"1.8","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"68.4","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"2.7","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.8","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"1.5","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.6","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"2.3","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"1.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.8","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"8.4","Cell RNA - THP-1 [nTPM]":"5.5","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.7","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"3.4","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"0.7","Brain RNA - basal ganglia [nTPM]":"0.7","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"1.1","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"0.7","Brain RNA - medulla oblongata [nTPM]":"0.8","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"0.8","Brain RNA - spinal cord [nTPM]":"0.7","Brain RNA - thalamus [nTPM]":"0.8","Brain RNA - white matter [nTPM]":"0.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.5","Single Cell Type RNA - Astrocytes [nTPM]":"2.9","Single Cell Type RNA - B-cells [nTPM]":"1.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"8.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"45.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"1.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"77.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.5","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"1.8","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"3.1","Single Cell Type RNA - Muller glia cells [nTPM]":"1.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.2","Single Cell Type RNA - Paneth cells [nTPM]":"8.1","Single Cell Type RNA - Peritubular cells [nTPM]":"5.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"33.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"151.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"25.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.4","Single Cell Type RNA - Theca cells [nTPM]":"1.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.9","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"ABCD1","Gene synonym":["adrenoleukodystrophy","ALD","ALDP","AMN"],"Ensembl":"ENSG00000101986","Gene description":"ATP binding cassette subfamily D member 1","Uniprot":["P33897"],"Chromosome":"X","Position":"153724856-153744755","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"19.5","Proximal enterocytes":"39.2","Syncytiotrophoblasts":"27.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"36.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"69.7","PC-3":"50.0","SK-BR-3":"49.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035214"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035214":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.50e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Tissue RNA - adipose tissue [nTPM]":"14.6","Tissue RNA - adrenal gland [nTPM]":"33.3","Tissue RNA - amygdala [nTPM]":"3.1","Tissue RNA - appendix [nTPM]":"5.4","Tissue RNA - basal ganglia [nTPM]":"3.9","Tissue RNA - bone marrow [nTPM]":"4.7","Tissue RNA - breast [nTPM]":"12.5","Tissue RNA - cerebellum [nTPM]":"3.4","Tissue RNA - cerebral cortex [nTPM]":"3.8","Tissue RNA - cervix [nTPM]":"7.5","Tissue RNA - choroid plexus [nTPM]":"2.2","Tissue RNA - colon [nTPM]":"14.7","Tissue RNA - duodenum [nTPM]":"10.6","Tissue RNA - endometrium 1 [nTPM]":"33.2","Tissue RNA - epididymis [nTPM]":"1.7","Tissue RNA - esophagus [nTPM]":"3.7","Tissue RNA - fallopian tube [nTPM]":"9.3","Tissue RNA - gallbladder [nTPM]":"3.4","Tissue RNA - heart muscle [nTPM]":"11.9","Tissue RNA - hippocampal formation [nTPM]":"2.9","Tissue RNA - hypothalamus [nTPM]":"3.4","Tissue RNA - kidney [nTPM]":"7.0","Tissue RNA - liver [nTPM]":"13.3","Tissue RNA - lung [nTPM]":"7.6","Tissue RNA - lymph node [nTPM]":"3.9","Tissue RNA - medulla oblongata [nTPM]":"4.4","Tissue RNA - midbrain [nTPM]":"3.6","Tissue RNA - ovary [nTPM]":"5.4","Tissue RNA - pancreas [nTPM]":"11.9","Tissue RNA - parathyroid gland [nTPM]":"2.1","Tissue RNA - pituitary gland [nTPM]":"10.0","Tissue RNA - placenta [nTPM]":"4.7","Tissue RNA - pons [nTPM]":"4.8","Tissue RNA - prostate [nTPM]":"9.9","Tissue RNA - rectum [nTPM]":"1.8","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"6.2","Tissue RNA - seminal vesicle [nTPM]":"5.6","Tissue RNA - skeletal muscle [nTPM]":"20.5","Tissue RNA - skin 1 [nTPM]":"4.4","Tissue RNA - small intestine [nTPM]":"17.4","Tissue RNA - smooth muscle [nTPM]":"4.8","Tissue RNA - spinal cord [nTPM]":"3.1","Tissue RNA - spleen [nTPM]":"13.8","Tissue RNA - stomach 1 [nTPM]":"7.2","Tissue RNA - testis [nTPM]":"19.0","Tissue RNA - thalamus [nTPM]":"5.5","Tissue RNA - thymus [nTPM]":"4.3","Tissue RNA - thyroid gland [nTPM]":"6.0","Tissue RNA - tongue [nTPM]":"4.6","Tissue RNA - tonsil [nTPM]":"1.7","Tissue RNA - urinary bladder [nTPM]":"11.9","Tissue RNA - vagina [nTPM]":"6.1","Tissue RNA - white matter [nTPM]":"4.2","Cell RNA - A-431 [nTPM]":"13.2","Cell RNA - A549 [nTPM]":"4.0","Cell RNA - AF22 [nTPM]":"2.6","Cell RNA - AN3-CA [nTPM]":"11.2","Cell RNA - ASC diff [nTPM]":"7.4","Cell RNA - ASC TERT1 [nTPM]":"3.2","Cell RNA - BEWO [nTPM]":"34.3","Cell RNA - BJ [nTPM]":"6.3","Cell RNA - BJ hTERT+ [nTPM]":"6.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.4","Cell RNA - CACO-2 [nTPM]":"2.6","Cell RNA - CAPAN-2 [nTPM]":"7.1","Cell RNA - Daudi [nTPM]":"3.5","Cell RNA - EFO-21 [nTPM]":"69.7","Cell RNA - fHDF\/TERT166 [nTPM]":"8.6","Cell RNA - GAMG [nTPM]":"11.3","Cell RNA - HaCaT [nTPM]":"1.7","Cell RNA - HAP1 [nTPM]":"1.6","Cell RNA - HBEC3-KT [nTPM]":"1.4","Cell RNA - HBF TERT88 [nTPM]":"0.5","Cell RNA - HDLM-2 [nTPM]":"11.8","Cell RNA - HEK 293 [nTPM]":"2.1","Cell RNA - HEL [nTPM]":"10.3","Cell RNA - HeLa [nTPM]":"42.1","Cell RNA - Hep G2 [nTPM]":"34.1","Cell RNA - HHSteC [nTPM]":"9.8","Cell RNA - HL-60 [nTPM]":"6.4","Cell RNA - HMC-1 [nTPM]":"22.4","Cell RNA - HSkMC [nTPM]":"6.2","Cell RNA - hTCEpi [nTPM]":"1.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.8","Cell RNA - hTERT-HME1 [nTPM]":"0.4","Cell RNA - hTERT-RPE1 [nTPM]":"4.4","Cell RNA - HUVEC TERT2 [nTPM]":"6.7","Cell RNA - JURKAT [nTPM]":"4.7","Cell RNA - K-562 [nTPM]":"6.0","Cell RNA - Karpas-707 [nTPM]":"12.4","Cell RNA - LHCN-M2 [nTPM]":"5.9","Cell RNA - MCF7 [nTPM]":"4.7","Cell RNA - MOLT-4 [nTPM]":"4.5","Cell RNA - NB-4 [nTPM]":"6.1","Cell RNA - NTERA-2 [nTPM]":"3.3","Cell RNA - OE19 [nTPM]":"3.2","Cell RNA - PC-3 [nTPM]":"50.0","Cell RNA - REH [nTPM]":"7.8","Cell RNA - RH-30 [nTPM]":"6.2","Cell RNA - RPMI-8226 [nTPM]":"5.7","Cell RNA - RPTEC TERT1 [nTPM]":"3.2","Cell RNA - RT4 [nTPM]":"1.4","Cell RNA - SCLC-21H [nTPM]":"2.8","Cell RNA - SH-SY5Y [nTPM]":"11.5","Cell RNA - SiHa [nTPM]":"16.4","Cell RNA - SK-BR-3 [nTPM]":"49.2","Cell RNA - SK-MEL-30 [nTPM]":"26.4","Cell RNA - SuSa [nTPM]":"3.0","Cell RNA - T-47d [nTPM]":"3.7","Cell RNA - THP-1 [nTPM]":"10.8","Cell RNA - TIME [nTPM]":"7.9","Cell RNA - U-138 MG [nTPM]":"5.5","Cell RNA - U-2 OS [nTPM]":"7.4","Cell RNA - U-2197 [nTPM]":"14.3","Cell RNA - U-251 MG [nTPM]":"7.0","Cell RNA - U-266\/70 [nTPM]":"12.2","Cell RNA - U-266\/84 [nTPM]":"5.7","Cell RNA - U-698 [nTPM]":"8.4","Cell RNA - U-87 MG [nTPM]":"6.9","Cell RNA - U-937 [nTPM]":"21.7","Cell RNA - WM-115 [nTPM]":"7.8","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"3.2","Blood RNA - eosinophil [nTPM]":"2.5","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"3.0","Blood RNA - MAIT T-cell [nTPM]":"4.0","Blood RNA - memory B-cell [nTPM]":"1.0","Blood RNA - memory CD4 T-cell [nTPM]":"1.0","Blood RNA - memory CD8 T-cell [nTPM]":"1.2","Blood RNA - myeloid DC [nTPM]":"2.7","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"1.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.8","Blood RNA - neutrophil [nTPM]":"1.7","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"2.8","Blood RNA - plasmacytoid DC [nTPM]":"1.7","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"2.5","Brain RNA - amygdala [nTPM]":"3.1","Brain RNA - basal ganglia [nTPM]":"3.9","Brain RNA - cerebellum [nTPM]":"3.4","Brain RNA - cerebral cortex [nTPM]":"3.8","Brain RNA - hippocampal formation [nTPM]":"2.9","Brain RNA - hypothalamus [nTPM]":"3.4","Brain RNA - medulla oblongata [nTPM]":"4.4","Brain RNA - midbrain [nTPM]":"3.6","Brain RNA - pons [nTPM]":"4.8","Brain RNA - spinal cord [nTPM]":"3.1","Brain RNA - thalamus [nTPM]":"5.5","Brain RNA - white matter [nTPM]":"4.2","Single Cell Type RNA - Adipocytes [nTPM]":"5.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"3.6","Single Cell Type RNA - B-cells [nTPM]":"3.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"2.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"2.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.2","Single Cell Type RNA - dendritic cells [nTPM]":"4.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.5","Single Cell Type RNA - Endothelial cells [nTPM]":"3.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"3.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.5","Single Cell Type RNA - Fibroblasts [nTPM]":"4.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"6.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.7","Single Cell Type RNA - Hepatocytes [nTPM]":"6.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.6","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"15.9","Single Cell Type RNA - Langerhans cells [nTPM]":"8.4","Single Cell Type RNA - Late spermatids [nTPM]":"2.7","Single Cell Type RNA - Leydig cells [nTPM]":"4.1","Single Cell Type RNA - Macrophages [nTPM]":"12.3","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"5.9","Single Cell Type RNA - Muller glia cells [nTPM]":"2.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.0","Single Cell Type RNA - Paneth cells [nTPM]":"2.1","Single Cell Type RNA - Peritubular cells [nTPM]":"5.7","Single Cell Type RNA - Plasma cells [nTPM]":"2.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"39.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.8","Single Cell Type RNA - Spermatocytes [nTPM]":"3.8","Single Cell Type RNA - Spermatogonia [nTPM]":"4.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"27.4","Single Cell Type RNA - T-cells [nTPM]":"4.0","Single Cell Type RNA - Theca cells [nTPM]":"7.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.5","Single Cell Type RNA - Urothelial cells [nTPM]":"1.4"},{"Gene":"ABCD3","Gene synonym":["PMP70","PXMP1","ZWS2"],"Ensembl":"ENSG00000117528","Gene description":"ATP binding cassette subfamily D member 3","Uniprot":["P28288"],"Chromosome":"1","Position":"94418389-94518666","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"126.6"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032026","HPA032027","CAB032516","CAB075749"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Peroxisomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Peroxisomes"],"Subcellular additional location":null,"Antibody RRID":{"CAB032516":"AB_2257637","CAB075749":"AB_2665755","HPA032026":"AB_2674117","HPA032027":"AB_10602103"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.16e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.84e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Tissue RNA - adipose tissue [nTPM]":"16.8","Tissue RNA - adrenal gland [nTPM]":"18.7","Tissue RNA - amygdala [nTPM]":"19.8","Tissue RNA - appendix [nTPM]":"16.2","Tissue RNA - basal ganglia [nTPM]":"23.2","Tissue RNA - bone marrow [nTPM]":"25.1","Tissue RNA - breast [nTPM]":"32.8","Tissue RNA - cerebellum [nTPM]":"22.7","Tissue RNA - cerebral cortex [nTPM]":"24.3","Tissue RNA - cervix [nTPM]":"22.4","Tissue RNA - choroid plexus [nTPM]":"22.6","Tissue RNA - colon [nTPM]":"44.6","Tissue RNA - duodenum [nTPM]":"44.5","Tissue RNA - endometrium 1 [nTPM]":"14.7","Tissue RNA - epididymis [nTPM]":"21.2","Tissue RNA - esophagus [nTPM]":"26.7","Tissue RNA - fallopian tube [nTPM]":"16.7","Tissue RNA - gallbladder [nTPM]":"26.8","Tissue RNA - heart muscle [nTPM]":"26.0","Tissue RNA - hippocampal formation [nTPM]":"18.7","Tissue RNA - hypothalamus [nTPM]":"21.8","Tissue RNA - kidney [nTPM]":"59.4","Tissue RNA - liver [nTPM]":"126.6","Tissue RNA - lung [nTPM]":"23.3","Tissue RNA - lymph node [nTPM]":"13.3","Tissue RNA - medulla oblongata [nTPM]":"22.1","Tissue RNA - midbrain [nTPM]":"21.2","Tissue RNA - ovary [nTPM]":"10.1","Tissue RNA - pancreas [nTPM]":"28.6","Tissue RNA - parathyroid gland [nTPM]":"29.6","Tissue RNA - pituitary gland [nTPM]":"13.3","Tissue RNA - placenta [nTPM]":"14.4","Tissue RNA - pons [nTPM]":"22.7","Tissue RNA - prostate [nTPM]":"21.5","Tissue RNA - rectum [nTPM]":"40.2","Tissue RNA - retina [nTPM]":"26.3","Tissue RNA - salivary gland [nTPM]":"17.5","Tissue RNA - seminal vesicle [nTPM]":"27.0","Tissue RNA - skeletal muscle [nTPM]":"23.5","Tissue RNA - skin 1 [nTPM]":"35.5","Tissue RNA - small intestine [nTPM]":"46.1","Tissue RNA - smooth muscle [nTPM]":"17.7","Tissue RNA - spinal cord [nTPM]":"23.7","Tissue RNA - spleen [nTPM]":"11.0","Tissue RNA - stomach 1 [nTPM]":"43.5","Tissue RNA - testis [nTPM]":"16.3","Tissue RNA - thalamus [nTPM]":"21.4","Tissue RNA - thymus [nTPM]":"47.5","Tissue RNA - thyroid gland [nTPM]":"27.5","Tissue RNA - tongue [nTPM]":"29.8","Tissue RNA - tonsil [nTPM]":"21.2","Tissue RNA - urinary bladder [nTPM]":"22.9","Tissue RNA - vagina [nTPM]":"16.2","Tissue RNA - white matter [nTPM]":"27.3","Cell RNA - A-431 [nTPM]":"81.5","Cell RNA - A549 [nTPM]":"37.6","Cell RNA - AF22 [nTPM]":"37.8","Cell RNA - AN3-CA [nTPM]":"36.1","Cell RNA - ASC diff [nTPM]":"28.3","Cell RNA - ASC TERT1 [nTPM]":"31.0","Cell RNA - BEWO [nTPM]":"55.8","Cell RNA - BJ [nTPM]":"41.4","Cell RNA - BJ hTERT+ [nTPM]":"32.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"46.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"51.5","Cell RNA - CACO-2 [nTPM]":"117.5","Cell RNA - CAPAN-2 [nTPM]":"25.0","Cell RNA - Daudi [nTPM]":"49.8","Cell RNA - EFO-21 [nTPM]":"52.1","Cell RNA - fHDF\/TERT166 [nTPM]":"52.8","Cell RNA - GAMG [nTPM]":"50.0","Cell RNA - HaCaT [nTPM]":"58.2","Cell RNA - HAP1 [nTPM]":"43.7","Cell RNA - HBEC3-KT [nTPM]":"53.7","Cell RNA - HBF TERT88 [nTPM]":"64.9","Cell RNA - HDLM-2 [nTPM]":"40.1","Cell RNA - HEK 293 [nTPM]":"36.9","Cell RNA - HEL [nTPM]":"56.7","Cell RNA - HeLa [nTPM]":"52.3","Cell RNA - Hep G2 [nTPM]":"102.5","Cell RNA - HHSteC [nTPM]":"27.5","Cell RNA - HL-60 [nTPM]":"51.2","Cell RNA - HMC-1 [nTPM]":"17.0","Cell RNA - HSkMC [nTPM]":"26.2","Cell RNA - hTCEpi [nTPM]":"29.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"54.2","Cell RNA - hTERT-HME1 [nTPM]":"20.8","Cell RNA - hTERT-RPE1 [nTPM]":"30.2","Cell RNA - HUVEC TERT2 [nTPM]":"29.0","Cell RNA - JURKAT [nTPM]":"47.0","Cell RNA - K-562 [nTPM]":"25.8","Cell RNA - Karpas-707 [nTPM]":"29.2","Cell RNA - LHCN-M2 [nTPM]":"48.6","Cell RNA - MCF7 [nTPM]":"11.4","Cell RNA - MOLT-4 [nTPM]":"86.4","Cell RNA - NB-4 [nTPM]":"26.8","Cell RNA - NTERA-2 [nTPM]":"43.7","Cell RNA - OE19 [nTPM]":"61.7","Cell RNA - PC-3 [nTPM]":"50.7","Cell RNA - REH [nTPM]":"48.0","Cell RNA - RH-30 [nTPM]":"78.4","Cell RNA - RPMI-8226 [nTPM]":"19.4","Cell RNA - RPTEC TERT1 [nTPM]":"45.6","Cell RNA - RT4 [nTPM]":"122.2","Cell RNA - SCLC-21H [nTPM]":"28.5","Cell RNA - SH-SY5Y [nTPM]":"46.7","Cell RNA - SiHa [nTPM]":"71.5","Cell RNA - SK-BR-3 [nTPM]":"75.2","Cell RNA - SK-MEL-30 [nTPM]":"55.7","Cell RNA - SuSa [nTPM]":"28.4","Cell RNA - T-47d [nTPM]":"27.7","Cell RNA - THP-1 [nTPM]":"41.8","Cell RNA - TIME [nTPM]":"28.9","Cell RNA - U-138 MG [nTPM]":"34.5","Cell RNA - U-2 OS [nTPM]":"49.5","Cell RNA - U-2197 [nTPM]":"61.3","Cell RNA - U-251 MG [nTPM]":"55.9","Cell RNA - U-266\/70 [nTPM]":"16.5","Cell RNA - U-266\/84 [nTPM]":"16.5","Cell RNA - U-698 [nTPM]":"48.4","Cell RNA - U-87 MG [nTPM]":"27.1","Cell RNA - U-937 [nTPM]":"25.6","Cell RNA - WM-115 [nTPM]":"16.4","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"3.8","Blood RNA - eosinophil [nTPM]":"2.9","Blood RNA - gdT-cell [nTPM]":"4.2","Blood RNA - intermediate monocyte [nTPM]":"4.3","Blood RNA - MAIT T-cell [nTPM]":"4.0","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"3.8","Blood RNA - memory CD8 T-cell [nTPM]":"4.9","Blood RNA - myeloid DC [nTPM]":"5.9","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"4.5","Blood RNA - naive CD8 T-cell [nTPM]":"4.4","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"5.9","Blood RNA - non-classical monocyte [nTPM]":"3.8","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"4.6","Blood RNA - total PBMC [nTPM]":"3.3","Brain RNA - amygdala [nTPM]":"19.8","Brain RNA - basal ganglia [nTPM]":"23.2","Brain RNA - cerebellum [nTPM]":"22.7","Brain RNA - cerebral cortex [nTPM]":"24.3","Brain RNA - hippocampal formation [nTPM]":"18.7","Brain RNA - hypothalamus [nTPM]":"21.8","Brain RNA - medulla oblongata [nTPM]":"22.1","Brain RNA - midbrain [nTPM]":"21.2","Brain RNA - pons [nTPM]":"22.7","Brain RNA - spinal cord [nTPM]":"23.7","Brain RNA - thalamus [nTPM]":"21.4","Brain RNA - white matter [nTPM]":"27.3","Single Cell Type RNA - Adipocytes [nTPM]":"16.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"48.8","Single Cell Type RNA - Astrocytes [nTPM]":"64.3","Single Cell Type RNA - B-cells [nTPM]":"10.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"23.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"32.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"27.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"43.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"39.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"58.6","Single Cell Type RNA - Club cells [nTPM]":"43.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"42.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.0","Single Cell Type RNA - dendritic cells [nTPM]":"12.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"72.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"22.8","Single Cell Type RNA - Early spermatids [nTPM]":"9.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"37.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.8","Single Cell Type RNA - Endothelial cells [nTPM]":"16.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"39.7","Single Cell Type RNA - Erythroid cells [nTPM]":"8.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"32.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"44.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.0","Single Cell Type RNA - Fibroblasts [nTPM]":"18.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"37.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"30.6","Single Cell Type RNA - granulocytes [nTPM]":"27.9","Single Cell Type RNA - Granulosa cells [nTPM]":"19.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.2","Single Cell Type RNA - Hepatocytes [nTPM]":"108.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.0","Single Cell Type RNA - Horizontal cells [nTPM]":"33.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"47.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"37.5","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"21.9","Single Cell Type RNA - Langerhans cells [nTPM]":"7.4","Single Cell Type RNA - Late spermatids [nTPM]":"8.2","Single Cell Type RNA - Leydig cells [nTPM]":"13.7","Single Cell Type RNA - Macrophages [nTPM]":"15.0","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"40.3","Single Cell Type RNA - monocytes [nTPM]":"15.1","Single Cell Type RNA - Muller glia cells [nTPM]":"78.4","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"67.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"96.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"37.5","Single Cell Type RNA - Paneth cells [nTPM]":"33.0","Single Cell Type RNA - Peritubular cells [nTPM]":"24.5","Single Cell Type RNA - Plasma cells [nTPM]":"15.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"75.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"72.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"49.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"26.3","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.7","Single Cell Type RNA - Spermatocytes [nTPM]":"14.5","Single Cell Type RNA - Spermatogonia [nTPM]":"23.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"34.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.3","Single Cell Type RNA - T-cells [nTPM]":"15.4","Single Cell Type RNA - Theca cells [nTPM]":"16.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"39.5","Single Cell Type RNA - Urothelial cells [nTPM]":"32.5"},{"Gene":"ABCD4","Gene synonym":["EST352188","P70R","PMP69","PXMP1L"],"Ensembl":"ENSG00000119688","Gene description":"ATP binding cassette subfamily D member 4","Uniprot":["O14678"],"Chromosome":"14","Position":"74285269-74303055","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003396"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA003396":"AB_1078078"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-3"},"Tissue RNA - adipose tissue [nTPM]":"6.6","Tissue RNA - adrenal gland [nTPM]":"4.7","Tissue RNA - amygdala [nTPM]":"3.0","Tissue RNA - appendix [nTPM]":"3.9","Tissue RNA - basal ganglia [nTPM]":"3.4","Tissue RNA - bone marrow [nTPM]":"4.6","Tissue RNA - breast [nTPM]":"6.4","Tissue RNA - cerebellum [nTPM]":"4.0","Tissue RNA - cerebral cortex [nTPM]":"5.4","Tissue RNA - cervix [nTPM]":"5.8","Tissue RNA - choroid plexus [nTPM]":"2.9","Tissue RNA - colon [nTPM]":"5.4","Tissue RNA - duodenum [nTPM]":"8.8","Tissue RNA - endometrium 1 [nTPM]":"4.9","Tissue RNA - epididymis [nTPM]":"2.1","Tissue RNA - esophagus [nTPM]":"4.8","Tissue RNA - fallopian tube [nTPM]":"8.5","Tissue RNA - gallbladder [nTPM]":"7.7","Tissue RNA - heart muscle [nTPM]":"6.0","Tissue RNA - hippocampal formation [nTPM]":"3.0","Tissue RNA - hypothalamus [nTPM]":"3.3","Tissue RNA - kidney [nTPM]":"5.4","Tissue RNA - liver [nTPM]":"7.7","Tissue RNA - lung [nTPM]":"5.8","Tissue RNA - lymph node [nTPM]":"6.6","Tissue RNA - medulla oblongata [nTPM]":"4.2","Tissue RNA - midbrain [nTPM]":"3.4","Tissue RNA - ovary [nTPM]":"6.9","Tissue RNA - pancreas [nTPM]":"6.0","Tissue RNA - parathyroid gland [nTPM]":"3.8","Tissue RNA - pituitary gland [nTPM]":"3.9","Tissue RNA - placenta [nTPM]":"7.4","Tissue RNA - pons [nTPM]":"3.7","Tissue RNA - prostate [nTPM]":"3.6","Tissue RNA - rectum [nTPM]":"4.0","Tissue RNA - retina [nTPM]":"3.3","Tissue RNA - salivary gland [nTPM]":"4.0","Tissue RNA - seminal vesicle [nTPM]":"3.5","Tissue RNA - skeletal muscle [nTPM]":"3.9","Tissue RNA - skin 1 [nTPM]":"4.1","Tissue RNA - small intestine [nTPM]":"8.7","Tissue RNA - smooth muscle [nTPM]":"5.2","Tissue RNA - spinal cord [nTPM]":"2.8","Tissue RNA - spleen [nTPM]":"6.2","Tissue RNA - stomach 1 [nTPM]":"4.5","Tissue RNA - testis [nTPM]":"3.4","Tissue RNA - thalamus [nTPM]":"3.6","Tissue RNA - thymus [nTPM]":"5.5","Tissue RNA - thyroid gland [nTPM]":"7.2","Tissue RNA - tongue [nTPM]":"2.0","Tissue RNA - tonsil [nTPM]":"3.8","Tissue RNA - urinary bladder [nTPM]":"4.5","Tissue RNA - vagina [nTPM]":"4.3","Tissue RNA - white matter [nTPM]":"4.5","Cell RNA - A-431 [nTPM]":"2.6","Cell RNA - A549 [nTPM]":"3.1","Cell RNA - AF22 [nTPM]":"7.9","Cell RNA - AN3-CA [nTPM]":"6.2","Cell RNA - ASC diff [nTPM]":"6.4","Cell RNA - ASC TERT1 [nTPM]":"4.3","Cell RNA - BEWO [nTPM]":"9.8","Cell RNA - BJ [nTPM]":"3.9","Cell RNA - BJ hTERT+ [nTPM]":"5.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.0","Cell RNA - CACO-2 [nTPM]":"6.5","Cell RNA - CAPAN-2 [nTPM]":"13.7","Cell RNA - Daudi [nTPM]":"4.3","Cell RNA - EFO-21 [nTPM]":"7.4","Cell RNA - fHDF\/TERT166 [nTPM]":"5.9","Cell RNA - GAMG [nTPM]":"3.2","Cell RNA - HaCaT [nTPM]":"9.2","Cell RNA - HAP1 [nTPM]":"6.0","Cell RNA - HBEC3-KT [nTPM]":"5.4","Cell RNA - HBF TERT88 [nTPM]":"3.0","Cell RNA - HDLM-2 [nTPM]":"3.9","Cell RNA - HEK 293 [nTPM]":"3.8","Cell RNA - HEL [nTPM]":"2.3","Cell RNA - HeLa [nTPM]":"5.1","Cell RNA - Hep G2 [nTPM]":"5.2","Cell RNA - HHSteC [nTPM]":"2.1","Cell RNA - HL-60 [nTPM]":"2.9","Cell RNA - HMC-1 [nTPM]":"4.4","Cell RNA - HSkMC [nTPM]":"10.4","Cell RNA - hTCEpi [nTPM]":"2.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.1","Cell RNA - hTERT-HME1 [nTPM]":"2.8","Cell RNA - hTERT-RPE1 [nTPM]":"3.0","Cell RNA - HUVEC TERT2 [nTPM]":"9.9","Cell RNA - JURKAT [nTPM]":"5.4","Cell RNA - K-562 [nTPM]":"4.3","Cell RNA - Karpas-707 [nTPM]":"1.9","Cell RNA - LHCN-M2 [nTPM]":"4.5","Cell RNA - MCF7 [nTPM]":"4.3","Cell RNA - MOLT-4 [nTPM]":"7.1","Cell RNA - NB-4 [nTPM]":"5.6","Cell RNA - NTERA-2 [nTPM]":"3.0","Cell RNA - OE19 [nTPM]":"5.0","Cell RNA - PC-3 [nTPM]":"5.9","Cell RNA - REH [nTPM]":"9.7","Cell RNA - RH-30 [nTPM]":"11.4","Cell RNA - RPMI-8226 [nTPM]":"6.3","Cell RNA - RPTEC TERT1 [nTPM]":"8.6","Cell RNA - RT4 [nTPM]":"8.5","Cell RNA - SCLC-21H [nTPM]":"3.7","Cell RNA - SH-SY5Y [nTPM]":"7.3","Cell RNA - SiHa [nTPM]":"5.4","Cell RNA - SK-BR-3 [nTPM]":"5.3","Cell RNA - SK-MEL-30 [nTPM]":"5.5","Cell RNA - SuSa [nTPM]":"3.7","Cell RNA - T-47d [nTPM]":"12.3","Cell RNA - THP-1 [nTPM]":"1.7","Cell RNA - TIME [nTPM]":"9.7","Cell RNA - U-138 MG [nTPM]":"3.6","Cell RNA - U-2 OS [nTPM]":"7.0","Cell RNA - U-2197 [nTPM]":"3.2","Cell RNA - U-251 MG [nTPM]":"2.5","Cell RNA - U-266\/70 [nTPM]":"4.4","Cell RNA - U-266\/84 [nTPM]":"4.5","Cell RNA - U-698 [nTPM]":"3.3","Cell RNA - U-87 MG [nTPM]":"5.1","Cell RNA - U-937 [nTPM]":"4.3","Cell RNA - WM-115 [nTPM]":"4.5","Blood RNA - basophil [nTPM]":"6.0","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"1.8","Blood RNA - gdT-cell [nTPM]":"2.6","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"1.7","Blood RNA - memory B-cell [nTPM]":"1.9","Blood RNA - memory CD4 T-cell [nTPM]":"2.2","Blood RNA - memory CD8 T-cell [nTPM]":"2.9","Blood RNA - myeloid DC [nTPM]":"2.1","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"1.8","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"2.6","Blood RNA - non-classical monocyte [nTPM]":"1.0","Blood RNA - plasmacytoid DC [nTPM]":"4.0","Blood RNA - T-reg [nTPM]":"5.2","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"3.0","Brain RNA - basal ganglia [nTPM]":"3.4","Brain RNA - cerebellum [nTPM]":"4.0","Brain RNA - cerebral cortex [nTPM]":"5.4","Brain RNA - hippocampal formation [nTPM]":"3.0","Brain RNA - hypothalamus [nTPM]":"3.3","Brain RNA - medulla oblongata [nTPM]":"4.2","Brain RNA - midbrain [nTPM]":"3.4","Brain RNA - pons [nTPM]":"3.7","Brain RNA - spinal cord [nTPM]":"2.8","Brain RNA - thalamus [nTPM]":"3.6","Brain RNA - white matter [nTPM]":"4.5","Single Cell Type RNA - Adipocytes [nTPM]":"50.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.6","Single Cell Type RNA - Astrocytes [nTPM]":"32.3","Single Cell Type RNA - B-cells [nTPM]":"16.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"23.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.0","Single Cell Type RNA - Bipolar cells [nTPM]":"46.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"34.3","Single Cell Type RNA - Club cells [nTPM]":"21.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"64.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"51.6","Single Cell Type RNA - dendritic cells [nTPM]":"28.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"31.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"25.3","Single Cell Type RNA - Early spermatids [nTPM]":"10.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.5","Single Cell Type RNA - Endothelial cells [nTPM]":"50.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.0","Single Cell Type RNA - Erythroid cells [nTPM]":"9.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"29.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.9","Single Cell Type RNA - Fibroblasts [nTPM]":"23.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.1","Single Cell Type RNA - granulocytes [nTPM]":"20.3","Single Cell Type RNA - Granulosa cells [nTPM]":"43.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"44.6","Single Cell Type RNA - Hepatocytes [nTPM]":"23.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"51.1","Single Cell Type RNA - Horizontal cells [nTPM]":"32.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"34.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.7","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"24.8","Single Cell Type RNA - Langerhans cells [nTPM]":"27.1","Single Cell Type RNA - Late spermatids [nTPM]":"7.7","Single Cell Type RNA - Leydig cells [nTPM]":"40.4","Single Cell Type RNA - Macrophages [nTPM]":"19.5","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"22.8","Single Cell Type RNA - Muller glia cells [nTPM]":"36.4","Single Cell Type RNA - NK-cells [nTPM]":"32.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"23.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"38.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.9","Single Cell Type RNA - Paneth cells [nTPM]":"19.4","Single Cell Type RNA - Peritubular cells [nTPM]":"25.2","Single Cell Type RNA - Plasma cells [nTPM]":"13.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"60.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"55.5","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.1","Single Cell Type RNA - Spermatocytes [nTPM]":"35.8","Single Cell Type RNA - Spermatogonia [nTPM]":"27.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"28.5","Single Cell Type RNA - T-cells [nTPM]":"23.4","Single Cell Type RNA - Theca cells [nTPM]":"27.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"22.9","Single Cell Type RNA - Urothelial cells [nTPM]":"16.7"},{"Gene":"ABCG5","Gene synonym":["STSL"],"Ensembl":"ENSG00000138075","Gene description":"ATP binding cassette subfamily G member 5","Uniprot":["Q9H222"],"Chromosome":"2","Position":"43812472-43838865","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"69","RNA tissue specific nTPM":{"intestine":"47.8","liver":"62.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Hepatocytes":"60.3","Paneth cells":"23.9","Proximal enterocytes":"30.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"23","RNA cancer specific FPKM":{"liver cancer":"11.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"54","RNA cell line specific nTPM":{"Hep G2":"7.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.60e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"47.8","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.7","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"62.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"46.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"7.5","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"60.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"23.9","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"30.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.7","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"ABCG8","Gene synonym":["GBD4"],"Ensembl":"ENSG00000143921","Gene description":"ATP binding cassette subfamily G member 8","Uniprot":["Q9H221"],"Chromosome":"2","Position":"43831942-43882988","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"40","RNA tissue specific nTPM":{"intestine":"31.5","liver":"63.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hepatocytes":"32.0","Proximal enterocytes":"13.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"30","RNA cancer specific FPKM":{"liver cancer":"21.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"44","RNA cell line specific nTPM":{"Hep G2":"5.3"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019556"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA019556":"AB_1844444"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.86e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"1.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"29.8","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.9","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.4","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"63.4","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"31.5","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.7","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"5.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"1.1","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.4","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.7","Brain RNA - white matter [nTPM]":"0.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"32.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"5.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"ABHD12","Gene synonym":["ABHD12A","BEM46L2","C20orf22","dJ965G21.2","DKFZP434P106"],"Ensembl":"ENSG00000100997","Gene description":"Abhydrolase domain containing 12, lysophospholipase","Uniprot":["Q8N2K0"],"Chromosome":"20","Position":"25294742-25390835","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Cataract","Deafness","Disease variant","Neuropathy","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"315.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026866"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026866":"AB_1844446"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.81e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.30e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.18e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.91e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-3"},"Tissue RNA - adipose tissue [nTPM]":"29.5","Tissue RNA - adrenal gland [nTPM]":"33.0","Tissue RNA - amygdala [nTPM]":"55.7","Tissue RNA - appendix [nTPM]":"27.4","Tissue RNA - basal ganglia [nTPM]":"67.3","Tissue RNA - bone marrow [nTPM]":"26.5","Tissue RNA - breast [nTPM]":"26.9","Tissue RNA - cerebellum [nTPM]":"70.0","Tissue RNA - cerebral cortex [nTPM]":"64.7","Tissue RNA - cervix [nTPM]":"32.1","Tissue RNA - choroid plexus [nTPM]":"35.9","Tissue RNA - colon [nTPM]":"37.0","Tissue RNA - duodenum [nTPM]":"47.0","Tissue RNA - endometrium 1 [nTPM]":"25.3","Tissue RNA - epididymis [nTPM]":"133.1","Tissue RNA - esophagus [nTPM]":"50.0","Tissue RNA - fallopian tube [nTPM]":"24.8","Tissue RNA - gallbladder [nTPM]":"33.4","Tissue RNA - heart muscle [nTPM]":"30.5","Tissue RNA - hippocampal formation [nTPM]":"77.3","Tissue RNA - hypothalamus [nTPM]":"58.2","Tissue RNA - kidney [nTPM]":"45.5","Tissue RNA - liver [nTPM]":"29.8","Tissue RNA - lung [nTPM]":"32.6","Tissue RNA - lymph node [nTPM]":"30.8","Tissue RNA - medulla oblongata [nTPM]":"70.9","Tissue RNA - midbrain [nTPM]":"64.6","Tissue RNA - ovary [nTPM]":"30.6","Tissue RNA - pancreas [nTPM]":"117.8","Tissue RNA - parathyroid gland [nTPM]":"55.3","Tissue RNA - pituitary gland [nTPM]":"42.1","Tissue RNA - placenta [nTPM]":"29.6","Tissue RNA - pons [nTPM]":"73.3","Tissue RNA - prostate [nTPM]":"35.5","Tissue RNA - rectum [nTPM]":"36.4","Tissue RNA - retina [nTPM]":"30.8","Tissue RNA - salivary gland [nTPM]":"36.9","Tissue RNA - seminal vesicle [nTPM]":"39.9","Tissue RNA - skeletal muscle [nTPM]":"13.3","Tissue RNA - skin 1 [nTPM]":"52.4","Tissue RNA - small intestine [nTPM]":"52.8","Tissue RNA - smooth muscle [nTPM]":"23.6","Tissue RNA - spinal cord [nTPM]":"66.0","Tissue RNA - spleen [nTPM]":"22.0","Tissue RNA - stomach 1 [nTPM]":"55.0","Tissue RNA - testis [nTPM]":"19.2","Tissue RNA - thalamus [nTPM]":"71.8","Tissue RNA - thymus [nTPM]":"23.4","Tissue RNA - thyroid gland [nTPM]":"80.8","Tissue RNA - tongue [nTPM]":"14.8","Tissue RNA - tonsil [nTPM]":"41.5","Tissue RNA - urinary bladder [nTPM]":"37.2","Tissue RNA - vagina [nTPM]":"35.1","Tissue RNA - white matter [nTPM]":"96.9","Cell RNA - A-431 [nTPM]":"67.2","Cell RNA - A549 [nTPM]":"148.3","Cell RNA - AF22 [nTPM]":"41.6","Cell RNA - AN3-CA [nTPM]":"50.9","Cell RNA - ASC diff [nTPM]":"79.6","Cell RNA - ASC TERT1 [nTPM]":"47.1","Cell RNA - BEWO [nTPM]":"93.3","Cell RNA - BJ [nTPM]":"97.0","Cell RNA - BJ hTERT+ [nTPM]":"84.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"73.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"84.6","Cell RNA - CACO-2 [nTPM]":"90.1","Cell RNA - CAPAN-2 [nTPM]":"93.0","Cell RNA - Daudi [nTPM]":"21.8","Cell RNA - EFO-21 [nTPM]":"53.3","Cell RNA - fHDF\/TERT166 [nTPM]":"77.0","Cell RNA - GAMG [nTPM]":"155.1","Cell RNA - HaCaT [nTPM]":"116.5","Cell RNA - HAP1 [nTPM]":"44.4","Cell RNA - HBEC3-KT [nTPM]":"56.8","Cell RNA - HBF TERT88 [nTPM]":"62.8","Cell RNA - HDLM-2 [nTPM]":"22.7","Cell RNA - HEK 293 [nTPM]":"41.9","Cell RNA - HEL [nTPM]":"33.3","Cell RNA - HeLa [nTPM]":"46.8","Cell RNA - Hep G2 [nTPM]":"128.4","Cell RNA - HHSteC [nTPM]":"59.3","Cell RNA - HL-60 [nTPM]":"33.3","Cell RNA - HMC-1 [nTPM]":"71.6","Cell RNA - HSkMC [nTPM]":"58.7","Cell RNA - hTCEpi [nTPM]":"42.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"85.4","Cell RNA - hTERT-HME1 [nTPM]":"44.1","Cell RNA - hTERT-RPE1 [nTPM]":"95.7","Cell RNA - HUVEC TERT2 [nTPM]":"33.2","Cell RNA - JURKAT [nTPM]":"37.8","Cell RNA - K-562 [nTPM]":"25.8","Cell RNA - Karpas-707 [nTPM]":"315.3","Cell RNA - LHCN-M2 [nTPM]":"72.8","Cell RNA - MCF7 [nTPM]":"142.5","Cell RNA - MOLT-4 [nTPM]":"51.8","Cell RNA - NB-4 [nTPM]":"31.0","Cell RNA - NTERA-2 [nTPM]":"29.4","Cell RNA - OE19 [nTPM]":"77.8","Cell RNA - PC-3 [nTPM]":"96.8","Cell RNA - REH [nTPM]":"39.2","Cell RNA - RH-30 [nTPM]":"95.3","Cell RNA - RPMI-8226 [nTPM]":"195.0","Cell RNA - RPTEC TERT1 [nTPM]":"43.4","Cell RNA - RT4 [nTPM]":"145.7","Cell RNA - SCLC-21H [nTPM]":"46.6","Cell RNA - SH-SY5Y [nTPM]":"39.7","Cell RNA - SiHa [nTPM]":"75.4","Cell RNA - SK-BR-3 [nTPM]":"198.9","Cell RNA - SK-MEL-30 [nTPM]":"133.8","Cell RNA - SuSa [nTPM]":"72.3","Cell RNA - T-47d [nTPM]":"67.4","Cell RNA - THP-1 [nTPM]":"47.6","Cell RNA - TIME [nTPM]":"44.6","Cell RNA - U-138 MG [nTPM]":"98.3","Cell RNA - U-2 OS [nTPM]":"63.0","Cell RNA - U-2197 [nTPM]":"57.1","Cell RNA - U-251 MG [nTPM]":"54.0","Cell RNA - U-266\/70 [nTPM]":"38.8","Cell RNA - U-266\/84 [nTPM]":"36.1","Cell RNA - U-698 [nTPM]":"33.4","Cell RNA - U-87 MG [nTPM]":"61.8","Cell RNA - U-937 [nTPM]":"38.7","Cell RNA - WM-115 [nTPM]":"57.3","Blood RNA - basophil [nTPM]":"15.8","Blood RNA - classical monocyte [nTPM]":"18.8","Blood RNA - eosinophil [nTPM]":"17.3","Blood RNA - gdT-cell [nTPM]":"9.9","Blood RNA - intermediate monocyte [nTPM]":"17.0","Blood RNA - MAIT T-cell [nTPM]":"7.5","Blood RNA - memory B-cell [nTPM]":"3.8","Blood RNA - memory CD4 T-cell [nTPM]":"10.2","Blood RNA - memory CD8 T-cell [nTPM]":"13.7","Blood RNA - myeloid DC [nTPM]":"17.9","Blood RNA - naive B-cell [nTPM]":"5.1","Blood RNA - naive CD4 T-cell [nTPM]":"8.9","Blood RNA - naive CD8 T-cell [nTPM]":"8.9","Blood RNA - neutrophil [nTPM]":"3.6","Blood RNA - NK-cell [nTPM]":"15.4","Blood RNA - non-classical monocyte [nTPM]":"17.7","Blood RNA - plasmacytoid DC [nTPM]":"17.0","Blood RNA - T-reg [nTPM]":"10.4","Blood RNA - total PBMC [nTPM]":"8.6","Brain RNA - amygdala [nTPM]":"55.7","Brain RNA - basal ganglia [nTPM]":"67.3","Brain RNA - cerebellum [nTPM]":"70.0","Brain RNA - cerebral cortex [nTPM]":"64.7","Brain RNA - hippocampal formation [nTPM]":"77.3","Brain RNA - hypothalamus [nTPM]":"58.2","Brain RNA - medulla oblongata [nTPM]":"70.9","Brain RNA - midbrain [nTPM]":"64.6","Brain RNA - pons [nTPM]":"73.3","Brain RNA - spinal cord [nTPM]":"66.0","Brain RNA - thalamus [nTPM]":"71.8","Brain RNA - white matter [nTPM]":"96.9","Single Cell Type RNA - Adipocytes [nTPM]":"20.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.5","Single Cell Type RNA - Astrocytes [nTPM]":"19.2","Single Cell Type RNA - B-cells [nTPM]":"13.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.4","Single Cell Type RNA - Bipolar cells [nTPM]":"34.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"19.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"13.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"91.6","Single Cell Type RNA - dendritic cells [nTPM]":"22.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"97.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"27.4","Single Cell Type RNA - Ductal cells [nTPM]":"33.7","Single Cell Type RNA - Early spermatids [nTPM]":"53.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"24.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.1","Single Cell Type RNA - Endothelial cells [nTPM]":"17.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"34.0","Single Cell Type RNA - Erythroid cells [nTPM]":"14.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"37.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"34.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"95.2","Single Cell Type RNA - Fibroblasts [nTPM]":"22.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"35.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"28.3","Single Cell Type RNA - granulocytes [nTPM]":"10.2","Single Cell Type RNA - Granulosa cells [nTPM]":"26.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.0","Single Cell Type RNA - Hepatocytes [nTPM]":"19.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"114.1","Single Cell Type RNA - Horizontal cells [nTPM]":"42.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"46.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.9","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"37.8","Single Cell Type RNA - Langerhans cells [nTPM]":"43.8","Single Cell Type RNA - Late spermatids [nTPM]":"107.1","Single Cell Type RNA - Leydig cells [nTPM]":"16.1","Single Cell Type RNA - Macrophages [nTPM]":"62.4","Single Cell Type RNA - Melanocytes [nTPM]":"33.8","Single Cell Type RNA - Microglial cells [nTPM]":"42.2","Single Cell Type RNA - monocytes [nTPM]":"58.7","Single Cell Type RNA - Muller glia cells [nTPM]":"44.1","Single Cell Type RNA - NK-cells [nTPM]":"23.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"50.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"67.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.9","Single Cell Type RNA - Paneth cells [nTPM]":"77.7","Single Cell Type RNA - Peritubular cells [nTPM]":"20.7","Single Cell Type RNA - Plasma cells [nTPM]":"39.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"31.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"126.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"24.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.3","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.5","Single Cell Type RNA - Spermatocytes [nTPM]":"19.9","Single Cell Type RNA - Spermatogonia [nTPM]":"37.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"27.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"130.8","Single Cell Type RNA - T-cells [nTPM]":"18.0","Single Cell Type RNA - Theca cells [nTPM]":"19.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"33.3","Single Cell Type RNA - Urothelial cells [nTPM]":"35.2"},{"Gene":"ABHD5","Gene synonym":["CGI-58","NCIE2"],"Ensembl":"ENSG00000011198","Gene description":"Abhydrolase domain containing 5, lysophosphatidic acid acyltransferase","Uniprot":["Q8WTS1"],"Chromosome":"3","Position":"43690108-43734371","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Differentiation","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Cataract","Deafness","Disease variant","Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"205.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"67.8","neutrophil":"42.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"67.8"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB020685","HPA035851","HPA035852"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB020685":null,"HPA035851":"AB_10671942","HPA035852":"AB_10672073"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.89e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.17e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Tissue RNA - adipose tissue [nTPM]":"38.8","Tissue RNA - adrenal gland [nTPM]":"12.5","Tissue RNA - amygdala [nTPM]":"6.7","Tissue RNA - appendix [nTPM]":"8.5","Tissue RNA - basal ganglia [nTPM]":"8.6","Tissue RNA - bone marrow [nTPM]":"39.6","Tissue RNA - breast [nTPM]":"27.9","Tissue RNA - cerebellum [nTPM]":"10.5","Tissue RNA - cerebral cortex [nTPM]":"8.9","Tissue RNA - cervix [nTPM]":"9.8","Tissue RNA - choroid plexus [nTPM]":"6.0","Tissue RNA - colon [nTPM]":"12.3","Tissue RNA - duodenum [nTPM]":"9.9","Tissue RNA - endometrium 1 [nTPM]":"5.7","Tissue RNA - epididymis [nTPM]":"4.1","Tissue RNA - esophagus [nTPM]":"31.1","Tissue RNA - fallopian tube [nTPM]":"5.1","Tissue RNA - gallbladder [nTPM]":"11.6","Tissue RNA - heart muscle [nTPM]":"13.4","Tissue RNA - hippocampal formation [nTPM]":"6.8","Tissue RNA - hypothalamus [nTPM]":"7.4","Tissue RNA - kidney [nTPM]":"12.0","Tissue RNA - liver [nTPM]":"21.7","Tissue RNA - lung [nTPM]":"16.4","Tissue RNA - lymph node [nTPM]":"3.4","Tissue RNA - medulla oblongata [nTPM]":"9.2","Tissue RNA - midbrain [nTPM]":"8.2","Tissue RNA - ovary [nTPM]":"4.6","Tissue RNA - pancreas [nTPM]":"16.0","Tissue RNA - parathyroid gland [nTPM]":"12.2","Tissue RNA - pituitary gland [nTPM]":"5.6","Tissue RNA - placenta [nTPM]":"10.2","Tissue RNA - pons [nTPM]":"9.1","Tissue RNA - prostate [nTPM]":"7.1","Tissue RNA - rectum [nTPM]":"7.5","Tissue RNA - retina [nTPM]":"6.3","Tissue RNA - salivary gland [nTPM]":"27.4","Tissue RNA - seminal vesicle [nTPM]":"8.4","Tissue RNA - skeletal muscle [nTPM]":"15.0","Tissue RNA - skin 1 [nTPM]":"38.0","Tissue RNA - small intestine [nTPM]":"10.5","Tissue RNA - smooth muscle [nTPM]":"9.3","Tissue RNA - spinal cord [nTPM]":"9.3","Tissue RNA - spleen [nTPM]":"9.4","Tissue RNA - stomach 1 [nTPM]":"12.1","Tissue RNA - testis [nTPM]":"10.8","Tissue RNA - thalamus [nTPM]":"8.4","Tissue RNA - thymus [nTPM]":"6.8","Tissue RNA - thyroid gland [nTPM]":"15.5","Tissue RNA - tongue [nTPM]":"18.5","Tissue RNA - tonsil [nTPM]":"7.9","Tissue RNA - urinary bladder [nTPM]":"16.7","Tissue RNA - vagina [nTPM]":"16.9","Tissue RNA - white matter [nTPM]":"11.9","Cell RNA - A-431 [nTPM]":"18.9","Cell RNA - A549 [nTPM]":"6.8","Cell RNA - AF22 [nTPM]":"8.2","Cell RNA - AN3-CA [nTPM]":"9.7","Cell RNA - ASC diff [nTPM]":"32.0","Cell RNA - ASC TERT1 [nTPM]":"12.8","Cell RNA - BEWO [nTPM]":"17.1","Cell RNA - BJ [nTPM]":"77.4","Cell RNA - BJ hTERT+ [nTPM]":"27.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.9","Cell RNA - CACO-2 [nTPM]":"9.4","Cell RNA - CAPAN-2 [nTPM]":"6.4","Cell RNA - Daudi [nTPM]":"16.2","Cell RNA - EFO-21 [nTPM]":"10.9","Cell RNA - fHDF\/TERT166 [nTPM]":"23.2","Cell RNA - GAMG [nTPM]":"15.8","Cell RNA - HaCaT [nTPM]":"5.8","Cell RNA - HAP1 [nTPM]":"16.5","Cell RNA - HBEC3-KT [nTPM]":"18.5","Cell RNA - HBF TERT88 [nTPM]":"22.6","Cell RNA - HDLM-2 [nTPM]":"58.4","Cell RNA - HEK 293 [nTPM]":"13.2","Cell RNA - HEL [nTPM]":"36.6","Cell RNA - HeLa [nTPM]":"24.4","Cell RNA - Hep G2 [nTPM]":"7.5","Cell RNA - HHSteC [nTPM]":"15.7","Cell RNA - HL-60 [nTPM]":"9.2","Cell RNA - HMC-1 [nTPM]":"13.2","Cell RNA - HSkMC [nTPM]":"13.0","Cell RNA - hTCEpi [nTPM]":"64.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"31.3","Cell RNA - hTERT-HME1 [nTPM]":"28.5","Cell RNA - hTERT-RPE1 [nTPM]":"18.8","Cell RNA - HUVEC TERT2 [nTPM]":"33.3","Cell RNA - JURKAT [nTPM]":"10.8","Cell RNA - K-562 [nTPM]":"23.9","Cell RNA - Karpas-707 [nTPM]":"14.2","Cell RNA - LHCN-M2 [nTPM]":"46.9","Cell RNA - MCF7 [nTPM]":"11.0","Cell RNA - MOLT-4 [nTPM]":"7.6","Cell RNA - NB-4 [nTPM]":"6.9","Cell RNA - NTERA-2 [nTPM]":"22.8","Cell RNA - OE19 [nTPM]":"16.7","Cell RNA - PC-3 [nTPM]":"20.4","Cell RNA - REH [nTPM]":"3.1","Cell RNA - RH-30 [nTPM]":"24.1","Cell RNA - RPMI-8226 [nTPM]":"8.6","Cell RNA - RPTEC TERT1 [nTPM]":"27.9","Cell RNA - RT4 [nTPM]":"40.4","Cell RNA - SCLC-21H [nTPM]":"10.6","Cell RNA - SH-SY5Y [nTPM]":"13.6","Cell RNA - SiHa [nTPM]":"36.9","Cell RNA - SK-BR-3 [nTPM]":"20.5","Cell RNA - SK-MEL-30 [nTPM]":"9.8","Cell RNA - SuSa [nTPM]":"9.8","Cell RNA - T-47d [nTPM]":"18.9","Cell RNA - THP-1 [nTPM]":"8.9","Cell RNA - TIME [nTPM]":"19.3","Cell RNA - U-138 MG [nTPM]":"18.1","Cell RNA - U-2 OS [nTPM]":"13.6","Cell RNA - U-2197 [nTPM]":"35.0","Cell RNA - U-251 MG [nTPM]":"34.5","Cell RNA - U-266\/70 [nTPM]":"11.1","Cell RNA - U-266\/84 [nTPM]":"34.0","Cell RNA - U-698 [nTPM]":"7.7","Cell RNA - U-87 MG [nTPM]":"20.3","Cell RNA - U-937 [nTPM]":"17.3","Cell RNA - WM-115 [nTPM]":"16.0","Blood RNA - basophil [nTPM]":"67.8","Blood RNA - classical monocyte [nTPM]":"14.7","Blood RNA - eosinophil [nTPM]":"9.5","Blood RNA - gdT-cell [nTPM]":"2.3","Blood RNA - intermediate monocyte [nTPM]":"7.9","Blood RNA - MAIT T-cell [nTPM]":"1.7","Blood RNA - memory B-cell [nTPM]":"3.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.7","Blood RNA - memory CD8 T-cell [nTPM]":"2.7","Blood RNA - myeloid DC [nTPM]":"6.8","Blood RNA - naive B-cell [nTPM]":"4.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.6","Blood RNA - naive CD8 T-cell [nTPM]":"2.5","Blood RNA - neutrophil [nTPM]":"42.5","Blood RNA - NK-cell [nTPM]":"2.0","Blood RNA - non-classical monocyte [nTPM]":"5.7","Blood RNA - plasmacytoid DC [nTPM]":"1.9","Blood RNA - T-reg [nTPM]":"4.8","Blood RNA - total PBMC [nTPM]":"5.3","Brain RNA - amygdala [nTPM]":"6.7","Brain RNA - basal ganglia [nTPM]":"8.6","Brain RNA - cerebellum [nTPM]":"10.5","Brain RNA - cerebral cortex [nTPM]":"8.9","Brain RNA - hippocampal formation [nTPM]":"6.8","Brain RNA - hypothalamus [nTPM]":"7.4","Brain RNA - medulla oblongata [nTPM]":"9.2","Brain RNA - midbrain [nTPM]":"8.2","Brain RNA - pons [nTPM]":"9.1","Brain RNA - spinal cord [nTPM]":"9.3","Brain RNA - thalamus [nTPM]":"8.4","Brain RNA - white matter [nTPM]":"11.9","Single Cell Type RNA - Adipocytes [nTPM]":"117.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"51.8","Single Cell Type RNA - Astrocytes [nTPM]":"12.7","Single Cell Type RNA - B-cells [nTPM]":"44.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"39.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"25.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"88.8","Single Cell Type RNA - Bipolar cells [nTPM]":"11.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"149.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"116.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"49.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.7","Single Cell Type RNA - dendritic cells [nTPM]":"80.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"65.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"57.5","Single Cell Type RNA - Early spermatids [nTPM]":"19.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"47.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"49.0","Single Cell Type RNA - Endothelial cells [nTPM]":"34.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"36.2","Single Cell Type RNA - Erythroid cells [nTPM]":"69.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"24.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"61.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"24.9","Single Cell Type RNA - Fibroblasts [nTPM]":"53.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"67.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"114.0","Single Cell Type RNA - granulocytes [nTPM]":"16.5","Single Cell Type RNA - Granulosa cells [nTPM]":"8.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.2","Single Cell Type RNA - Hepatocytes [nTPM]":"12.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.7","Single Cell Type RNA - Ionocytes [nTPM]":"34.6","Single Cell Type RNA - Kupffer cells [nTPM]":"44.1","Single Cell Type RNA - Langerhans cells [nTPM]":"17.4","Single Cell Type RNA - Late spermatids [nTPM]":"17.1","Single Cell Type RNA - Leydig cells [nTPM]":"5.3","Single Cell Type RNA - Macrophages [nTPM]":"79.8","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"35.9","Single Cell Type RNA - Muller glia cells [nTPM]":"11.0","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"28.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"75.2","Single Cell Type RNA - Paneth cells [nTPM]":"49.8","Single Cell Type RNA - Peritubular cells [nTPM]":"5.7","Single Cell Type RNA - Plasma cells [nTPM]":"41.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"25.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"98.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"39.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"32.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"46.4","Single Cell Type RNA - Spermatocytes [nTPM]":"47.3","Single Cell Type RNA - Spermatogonia [nTPM]":"41.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"111.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"40.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"205.4","Single Cell Type RNA - T-cells [nTPM]":"42.6","Single Cell Type RNA - Theca cells [nTPM]":"15.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"21.9","Single Cell Type RNA - Urothelial cells [nTPM]":"71.6"},{"Gene":"ACACA","Gene synonym":["ACAC","ACC","ACC1"],"Ensembl":"ENSG00000278540","Gene description":"Acetyl-CoA carboxylase alpha","Uniprot":["Q13085"],"Chromosome":"17","Position":"37084992-37406836","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Allosteric enzyme","Ligase","Multifunctional enzyme"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"138.1","Excitatory neurons":"230.7","Inhibitory neurons":"197.8","Oligodendrocyte precursor cells":"181.0","Oligodendrocytes":"186.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013715","HPA036650","HPA063018"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli fibrillar center","Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoli fibrillar center","Actin filaments"],"Antibody RRID":{"CAB013715":null,"HPA036650":"AB_2675228","HPA063018":"AB_2684922"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.24e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Tissue RNA - adipose tissue [nTPM]":"16.2","Tissue RNA - adrenal gland [nTPM]":"25.4","Tissue RNA - amygdala [nTPM]":"10.8","Tissue RNA - appendix [nTPM]":"3.7","Tissue RNA - basal ganglia [nTPM]":"10.8","Tissue RNA - bone marrow [nTPM]":"4.9","Tissue RNA - breast [nTPM]":"22.2","Tissue RNA - cerebellum [nTPM]":"9.0","Tissue RNA - cerebral cortex [nTPM]":"15.8","Tissue RNA - cervix [nTPM]":"11.5","Tissue RNA - choroid plexus [nTPM]":"11.3","Tissue RNA - colon [nTPM]":"14.4","Tissue RNA - duodenum [nTPM]":"5.2","Tissue RNA - endometrium 1 [nTPM]":"12.1","Tissue RNA - epididymis [nTPM]":"13.8","Tissue RNA - esophagus [nTPM]":"25.2","Tissue RNA - fallopian tube [nTPM]":"10.8","Tissue RNA - gallbladder [nTPM]":"4.8","Tissue RNA - heart muscle [nTPM]":"7.7","Tissue RNA - hippocampal formation [nTPM]":"9.5","Tissue RNA - hypothalamus [nTPM]":"11.2","Tissue RNA - kidney [nTPM]":"13.6","Tissue RNA - liver [nTPM]":"23.3","Tissue RNA - lung [nTPM]":"13.3","Tissue RNA - lymph node [nTPM]":"2.0","Tissue RNA - medulla oblongata [nTPM]":"11.1","Tissue RNA - midbrain [nTPM]":"9.9","Tissue RNA - ovary [nTPM]":"11.3","Tissue RNA - pancreas [nTPM]":"10.5","Tissue RNA - parathyroid gland [nTPM]":"10.9","Tissue RNA - pituitary gland [nTPM]":"19.2","Tissue RNA - placenta [nTPM]":"3.8","Tissue RNA - pons [nTPM]":"11.1","Tissue RNA - prostate [nTPM]":"26.2","Tissue RNA - rectum [nTPM]":"6.4","Tissue RNA - retina [nTPM]":"8.0","Tissue RNA - salivary gland [nTPM]":"14.6","Tissue RNA - seminal vesicle [nTPM]":"9.6","Tissue RNA - skeletal muscle [nTPM]":"15.1","Tissue RNA - skin 1 [nTPM]":"15.4","Tissue RNA - small intestine [nTPM]":"9.6","Tissue RNA - smooth muscle [nTPM]":"8.0","Tissue RNA - spinal cord [nTPM]":"8.6","Tissue RNA - spleen [nTPM]":"7.3","Tissue RNA - stomach 1 [nTPM]":"12.6","Tissue RNA - testis [nTPM]":"16.4","Tissue RNA - thalamus [nTPM]":"10.3","Tissue RNA - thymus [nTPM]":"3.7","Tissue RNA - thyroid gland [nTPM]":"8.9","Tissue RNA - tongue [nTPM]":"3.6","Tissue RNA - tonsil [nTPM]":"5.5","Tissue RNA - urinary bladder [nTPM]":"19.9","Tissue RNA - vagina [nTPM]":"14.6","Tissue RNA - white matter [nTPM]":"12.3","Cell RNA - A-431 [nTPM]":"34.7","Cell RNA - A549 [nTPM]":"7.0","Cell RNA - AF22 [nTPM]":"39.8","Cell RNA - AN3-CA [nTPM]":"42.6","Cell RNA - ASC diff [nTPM]":"54.7","Cell RNA - ASC TERT1 [nTPM]":"53.2","Cell RNA - BEWO [nTPM]":"13.9","Cell RNA - BJ [nTPM]":"15.2","Cell RNA - BJ hTERT+ [nTPM]":"21.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"27.5","Cell RNA - CACO-2 [nTPM]":"27.4","Cell RNA - CAPAN-2 [nTPM]":"5.9","Cell RNA - Daudi [nTPM]":"5.0","Cell RNA - EFO-21 [nTPM]":"12.0","Cell RNA - fHDF\/TERT166 [nTPM]":"24.3","Cell RNA - GAMG [nTPM]":"39.4","Cell RNA - HaCaT [nTPM]":"33.9","Cell RNA - HAP1 [nTPM]":"7.5","Cell RNA - HBEC3-KT [nTPM]":"51.1","Cell RNA - HBF TERT88 [nTPM]":"23.7","Cell RNA - HDLM-2 [nTPM]":"13.6","Cell RNA - HEK 293 [nTPM]":"23.2","Cell RNA - HEL [nTPM]":"27.3","Cell RNA - HeLa [nTPM]":"15.5","Cell RNA - Hep G2 [nTPM]":"28.0","Cell RNA - HHSteC [nTPM]":"9.2","Cell RNA - HL-60 [nTPM]":"14.8","Cell RNA - HMC-1 [nTPM]":"5.3","Cell RNA - HSkMC [nTPM]":"43.4","Cell RNA - hTCEpi [nTPM]":"29.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"40.2","Cell RNA - hTERT-HME1 [nTPM]":"30.0","Cell RNA - hTERT-RPE1 [nTPM]":"18.8","Cell RNA - HUVEC TERT2 [nTPM]":"27.5","Cell RNA - JURKAT [nTPM]":"25.1","Cell RNA - K-562 [nTPM]":"66.5","Cell RNA - Karpas-707 [nTPM]":"3.2","Cell RNA - LHCN-M2 [nTPM]":"2.1","Cell RNA - MCF7 [nTPM]":"27.3","Cell RNA - MOLT-4 [nTPM]":"16.3","Cell RNA - NB-4 [nTPM]":"22.8","Cell RNA - NTERA-2 [nTPM]":"30.4","Cell RNA - OE19 [nTPM]":"21.5","Cell RNA - PC-3 [nTPM]":"22.1","Cell RNA - REH [nTPM]":"24.1","Cell RNA - RH-30 [nTPM]":"25.3","Cell RNA - RPMI-8226 [nTPM]":"6.4","Cell RNA - RPTEC TERT1 [nTPM]":"36.1","Cell RNA - RT4 [nTPM]":"38.5","Cell RNA - SCLC-21H [nTPM]":"45.0","Cell RNA - SH-SY5Y [nTPM]":"17.0","Cell RNA - SiHa [nTPM]":"27.8","Cell RNA - SK-BR-3 [nTPM]":"12.3","Cell RNA - SK-MEL-30 [nTPM]":"12.7","Cell RNA - SuSa [nTPM]":"34.8","Cell RNA - T-47d [nTPM]":"24.9","Cell RNA - THP-1 [nTPM]":"16.8","Cell RNA - TIME [nTPM]":"23.8","Cell RNA - U-138 MG [nTPM]":"12.7","Cell RNA - U-2 OS [nTPM]":"20.6","Cell RNA - U-2197 [nTPM]":"17.3","Cell RNA - U-251 MG [nTPM]":"3.9","Cell RNA - U-266\/70 [nTPM]":"8.7","Cell RNA - U-266\/84 [nTPM]":"11.5","Cell RNA - U-698 [nTPM]":"42.0","Cell RNA - U-87 MG [nTPM]":"11.7","Cell RNA - U-937 [nTPM]":"12.3","Cell RNA - WM-115 [nTPM]":"17.2","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.8","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"1.3","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.7","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"1.0","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.8","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"0.8","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"1.0","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"10.8","Brain RNA - basal ganglia [nTPM]":"10.8","Brain RNA - cerebellum [nTPM]":"9.0","Brain RNA - cerebral cortex [nTPM]":"15.8","Brain RNA - hippocampal formation [nTPM]":"9.5","Brain RNA - hypothalamus [nTPM]":"11.2","Brain RNA - medulla oblongata [nTPM]":"11.1","Brain RNA - midbrain [nTPM]":"9.9","Brain RNA - pons [nTPM]":"11.1","Brain RNA - spinal cord [nTPM]":"8.6","Brain RNA - thalamus [nTPM]":"10.3","Brain RNA - white matter [nTPM]":"12.3","Single Cell Type RNA - Adipocytes [nTPM]":"6.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"51.7","Single Cell Type RNA - Astrocytes [nTPM]":"138.1","Single Cell Type RNA - B-cells [nTPM]":"8.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.2","Single Cell Type RNA - Bipolar cells [nTPM]":"17.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"16.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.0","Single Cell Type RNA - dendritic cells [nTPM]":"7.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"6.7","Single Cell Type RNA - Early spermatids [nTPM]":"66.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.6","Single Cell Type RNA - Endothelial cells [nTPM]":"8.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.0","Single Cell Type RNA - Erythroid cells [nTPM]":"10.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"230.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.6","Single Cell Type RNA - Fibroblasts [nTPM]":"10.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.9","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"19.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"17.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.8","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"197.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.3","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"3.8","Single Cell Type RNA - Langerhans cells [nTPM]":"4.3","Single Cell Type RNA - Late spermatids [nTPM]":"51.2","Single Cell Type RNA - Leydig cells [nTPM]":"9.9","Single Cell Type RNA - Macrophages [nTPM]":"6.1","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"58.1","Single Cell Type RNA - monocytes [nTPM]":"4.3","Single Cell Type RNA - Muller glia cells [nTPM]":"18.2","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"181.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"186.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.2","Single Cell Type RNA - Paneth cells [nTPM]":"6.4","Single Cell Type RNA - Peritubular cells [nTPM]":"15.8","Single Cell Type RNA - Plasma cells [nTPM]":"9.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"22.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.8","Single Cell Type RNA - Spermatocytes [nTPM]":"20.8","Single Cell Type RNA - Spermatogonia [nTPM]":"20.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"27.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.3","Single Cell Type RNA - T-cells [nTPM]":"6.4","Single Cell Type RNA - Theca cells [nTPM]":"43.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.0","Single Cell Type RNA - Urothelial cells [nTPM]":"22.0"},{"Gene":"ACADM","Gene synonym":["ACAD1","MCAD","MCADH"],"Ensembl":"ENSG00000117054","Gene description":"Acyl-CoA dehydrogenase medium chain","Uniprot":["P11310"],"Chromosome":"1","Position":"75724431-75787575","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"367.3","skeletal muscle":"380.0","tongue":"475.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"373.1","Distal tubular cells":"344.4","Hepatocytes":"261.2","Proximal tubular cells":"564.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"289.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006198","HPA026542"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"930000","Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA006198":"AB_1078087","HPA026542":"AB_1844469"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.30e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.83e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Tissue RNA - adipose tissue [nTPM]":"81.9","Tissue RNA - adrenal gland [nTPM]":"82.2","Tissue RNA - amygdala [nTPM]":"25.2","Tissue RNA - appendix [nTPM]":"24.3","Tissue RNA - basal ganglia [nTPM]":"25.0","Tissue RNA - bone marrow [nTPM]":"17.3","Tissue RNA - breast [nTPM]":"69.9","Tissue RNA - cerebellum [nTPM]":"26.6","Tissue RNA - cerebral cortex [nTPM]":"42.2","Tissue RNA - cervix [nTPM]":"29.3","Tissue RNA - choroid plexus [nTPM]":"30.4","Tissue RNA - colon [nTPM]":"46.8","Tissue RNA - duodenum [nTPM]":"103.9","Tissue RNA - endometrium 1 [nTPM]":"20.0","Tissue RNA - epididymis [nTPM]":"25.3","Tissue RNA - esophagus [nTPM]":"51.3","Tissue RNA - fallopian tube [nTPM]":"30.6","Tissue RNA - gallbladder [nTPM]":"27.8","Tissue RNA - heart muscle [nTPM]":"217.8","Tissue RNA - hippocampal formation [nTPM]":"24.3","Tissue RNA - hypothalamus [nTPM]":"25.9","Tissue RNA - kidney [nTPM]":"295.9","Tissue RNA - liver [nTPM]":"367.3","Tissue RNA - lung [nTPM]":"22.6","Tissue RNA - lymph node [nTPM]":"42.6","Tissue RNA - medulla oblongata [nTPM]":"26.9","Tissue RNA - midbrain [nTPM]":"26.8","Tissue RNA - ovary [nTPM]":"35.7","Tissue RNA - pancreas [nTPM]":"35.9","Tissue RNA - parathyroid gland [nTPM]":"66.3","Tissue RNA - pituitary gland [nTPM]":"19.2","Tissue RNA - placenta [nTPM]":"16.9","Tissue RNA - pons [nTPM]":"25.8","Tissue RNA - prostate [nTPM]":"26.8","Tissue RNA - rectum [nTPM]":"49.5","Tissue RNA - retina [nTPM]":"21.2","Tissue RNA - salivary gland [nTPM]":"31.4","Tissue RNA - seminal vesicle [nTPM]":"26.2","Tissue RNA - skeletal muscle [nTPM]":"380.0","Tissue RNA - skin 1 [nTPM]":"14.4","Tissue RNA - small intestine [nTPM]":"75.6","Tissue RNA - smooth muscle [nTPM]":"25.5","Tissue RNA - spinal cord [nTPM]":"26.2","Tissue RNA - spleen [nTPM]":"27.4","Tissue RNA - stomach 1 [nTPM]":"52.8","Tissue RNA - testis [nTPM]":"35.7","Tissue RNA - thalamus [nTPM]":"25.8","Tissue RNA - thymus [nTPM]":"29.7","Tissue RNA - thyroid gland [nTPM]":"38.4","Tissue RNA - tongue [nTPM]":"475.9","Tissue RNA - tonsil [nTPM]":"44.3","Tissue RNA - urinary bladder [nTPM]":"32.7","Tissue RNA - vagina [nTPM]":"21.3","Tissue RNA - white matter [nTPM]":"25.2","Cell RNA - A-431 [nTPM]":"25.8","Cell RNA - A549 [nTPM]":"20.5","Cell RNA - AF22 [nTPM]":"61.0","Cell RNA - AN3-CA [nTPM]":"26.8","Cell RNA - ASC diff [nTPM]":"53.1","Cell RNA - ASC TERT1 [nTPM]":"42.1","Cell RNA - BEWO [nTPM]":"17.5","Cell RNA - BJ [nTPM]":"48.1","Cell RNA - BJ hTERT+ [nTPM]":"40.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"46.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"38.5","Cell RNA - CACO-2 [nTPM]":"38.3","Cell RNA - CAPAN-2 [nTPM]":"39.5","Cell RNA - Daudi [nTPM]":"289.1","Cell RNA - EFO-21 [nTPM]":"40.7","Cell RNA - fHDF\/TERT166 [nTPM]":"34.4","Cell RNA - GAMG [nTPM]":"39.0","Cell RNA - HaCaT [nTPM]":"22.8","Cell RNA - HAP1 [nTPM]":"54.9","Cell RNA - HBEC3-KT [nTPM]":"41.8","Cell RNA - HBF TERT88 [nTPM]":"57.8","Cell RNA - HDLM-2 [nTPM]":"113.0","Cell RNA - HEK 293 [nTPM]":"25.5","Cell RNA - HEL [nTPM]":"94.4","Cell RNA - HeLa [nTPM]":"58.5","Cell RNA - Hep G2 [nTPM]":"58.3","Cell RNA - HHSteC [nTPM]":"36.4","Cell RNA - HL-60 [nTPM]":"80.0","Cell RNA - HMC-1 [nTPM]":"23.9","Cell RNA - HSkMC [nTPM]":"50.7","Cell RNA - hTCEpi [nTPM]":"23.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"39.8","Cell RNA - hTERT-HME1 [nTPM]":"22.8","Cell RNA - hTERT-RPE1 [nTPM]":"35.0","Cell RNA - HUVEC TERT2 [nTPM]":"36.2","Cell RNA - JURKAT [nTPM]":"56.6","Cell RNA - K-562 [nTPM]":"102.3","Cell RNA - Karpas-707 [nTPM]":"60.4","Cell RNA - LHCN-M2 [nTPM]":"50.5","Cell RNA - MCF7 [nTPM]":"9.6","Cell RNA - MOLT-4 [nTPM]":"96.3","Cell RNA - NB-4 [nTPM]":"40.6","Cell RNA - NTERA-2 [nTPM]":"50.2","Cell RNA - OE19 [nTPM]":"80.4","Cell RNA - PC-3 [nTPM]":"49.5","Cell RNA - REH [nTPM]":"118.8","Cell RNA - RH-30 [nTPM]":"83.8","Cell RNA - RPMI-8226 [nTPM]":"30.6","Cell RNA - RPTEC TERT1 [nTPM]":"77.9","Cell RNA - RT4 [nTPM]":"70.7","Cell RNA - SCLC-21H [nTPM]":"33.8","Cell RNA - SH-SY5Y [nTPM]":"43.0","Cell RNA - SiHa [nTPM]":"38.0","Cell RNA - SK-BR-3 [nTPM]":"111.6","Cell RNA - SK-MEL-30 [nTPM]":"102.0","Cell RNA - SuSa [nTPM]":"43.1","Cell RNA - T-47d [nTPM]":"32.7","Cell RNA - THP-1 [nTPM]":"107.6","Cell RNA - TIME [nTPM]":"20.2","Cell RNA - U-138 MG [nTPM]":"29.9","Cell RNA - U-2 OS [nTPM]":"29.6","Cell RNA - U-2197 [nTPM]":"26.6","Cell RNA - U-251 MG [nTPM]":"78.1","Cell RNA - U-266\/70 [nTPM]":"38.6","Cell RNA - U-266\/84 [nTPM]":"62.0","Cell RNA - U-698 [nTPM]":"128.1","Cell RNA - U-87 MG [nTPM]":"25.8","Cell RNA - U-937 [nTPM]":"67.0","Cell RNA - WM-115 [nTPM]":"35.3","Blood RNA - basophil [nTPM]":"15.3","Blood RNA - classical monocyte [nTPM]":"14.2","Blood RNA - eosinophil [nTPM]":"19.3","Blood RNA - gdT-cell [nTPM]":"17.1","Blood RNA - intermediate monocyte [nTPM]":"20.9","Blood RNA - MAIT T-cell [nTPM]":"27.3","Blood RNA - memory B-cell [nTPM]":"40.7","Blood RNA - memory CD4 T-cell [nTPM]":"17.8","Blood RNA - memory CD8 T-cell [nTPM]":"21.5","Blood RNA - myeloid DC [nTPM]":"21.4","Blood RNA - naive B-cell [nTPM]":"24.6","Blood RNA - naive CD4 T-cell [nTPM]":"20.3","Blood RNA - naive CD8 T-cell [nTPM]":"23.6","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"25.0","Blood RNA - non-classical monocyte [nTPM]":"20.4","Blood RNA - plasmacytoid DC [nTPM]":"23.2","Blood RNA - T-reg [nTPM]":"19.5","Blood RNA - total PBMC [nTPM]":"19.5","Brain RNA - amygdala [nTPM]":"25.2","Brain RNA - basal ganglia [nTPM]":"25.0","Brain RNA - cerebellum [nTPM]":"26.6","Brain RNA - cerebral cortex [nTPM]":"42.2","Brain RNA - hippocampal formation [nTPM]":"24.3","Brain RNA - hypothalamus [nTPM]":"25.9","Brain RNA - medulla oblongata [nTPM]":"26.9","Brain RNA - midbrain [nTPM]":"26.8","Brain RNA - pons [nTPM]":"25.8","Brain RNA - spinal cord [nTPM]":"26.2","Brain RNA - thalamus [nTPM]":"25.8","Brain RNA - white matter [nTPM]":"25.2","Single Cell Type RNA - Adipocytes [nTPM]":"42.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"57.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"58.3","Single Cell Type RNA - Astrocytes [nTPM]":"29.7","Single Cell Type RNA - B-cells [nTPM]":"56.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"27.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"41.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"69.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"44.3","Single Cell Type RNA - Bipolar cells [nTPM]":"39.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"49.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"40.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"373.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"52.9","Single Cell Type RNA - Club cells [nTPM]":"63.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"58.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"35.8","Single Cell Type RNA - dendritic cells [nTPM]":"39.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"42.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"344.4","Single Cell Type RNA - Ductal cells [nTPM]":"37.9","Single Cell Type RNA - Early spermatids [nTPM]":"55.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"32.2","Single Cell Type RNA - Endothelial cells [nTPM]":"36.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"40.7","Single Cell Type RNA - Erythroid cells [nTPM]":"67.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"51.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.5","Single Cell Type RNA - Fibroblasts [nTPM]":"47.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"26.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.4","Single Cell Type RNA - granulocytes [nTPM]":"44.9","Single Cell Type RNA - Granulosa cells [nTPM]":"61.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"43.9","Single Cell Type RNA - Hepatocytes [nTPM]":"261.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"75.7","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"46.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"38.7","Single Cell Type RNA - Ionocytes [nTPM]":"63.1","Single Cell Type RNA - Kupffer cells [nTPM]":"45.6","Single Cell Type RNA - Langerhans cells [nTPM]":"22.2","Single Cell Type RNA - Late spermatids [nTPM]":"24.4","Single Cell Type RNA - Leydig cells [nTPM]":"46.9","Single Cell Type RNA - Macrophages [nTPM]":"38.2","Single Cell Type RNA - Melanocytes [nTPM]":"51.6","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"32.8","Single Cell Type RNA - Muller glia cells [nTPM]":"53.7","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"36.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"36.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.2","Single Cell Type RNA - Paneth cells [nTPM]":"49.7","Single Cell Type RNA - Peritubular cells [nTPM]":"45.5","Single Cell Type RNA - Plasma cells [nTPM]":"74.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"24.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"88.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"564.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"106.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"30.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"38.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"43.7","Single Cell Type RNA - Spermatocytes [nTPM]":"76.3","Single Cell Type RNA - Spermatogonia [nTPM]":"86.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"46.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.3","Single Cell Type RNA - T-cells [nTPM]":"39.4","Single Cell Type RNA - Theca cells [nTPM]":"72.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"46.7","Single Cell Type RNA - Urothelial cells [nTPM]":"35.9"},{"Gene":"ACADS","Gene synonym":["ACAD3","SCAD"],"Ensembl":"ENSG00000122971","Gene description":"Acyl-CoA dehydrogenase short chain","Uniprot":["P16219"],"Chromosome":"12","Position":"120725774-120740008","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"245.5","skeletal muscle":"158.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"303.1","Hepatocytes":"203.3","Paneth cells":"185.7","Proximal enterocytes":"435.0","Undifferentiated cells":"185.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"36.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004799","CAB019284","HPA022271"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB019284":null,"HPA004799":"AB_1844471","HPA022271":"AB_1844472"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.05e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.43e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.33e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.34e-5"},"Tissue RNA - adipose tissue [nTPM]":"50.3","Tissue RNA - adrenal gland [nTPM]":"52.7","Tissue RNA - amygdala [nTPM]":"13.3","Tissue RNA - appendix [nTPM]":"11.1","Tissue RNA - basal ganglia [nTPM]":"15.4","Tissue RNA - bone marrow [nTPM]":"14.3","Tissue RNA - breast [nTPM]":"40.9","Tissue RNA - cerebellum [nTPM]":"13.6","Tissue RNA - cerebral cortex [nTPM]":"16.6","Tissue RNA - cervix [nTPM]":"11.2","Tissue RNA - choroid plexus [nTPM]":"13.7","Tissue RNA - colon [nTPM]":"74.0","Tissue RNA - duodenum [nTPM]":"84.8","Tissue RNA - endometrium 1 [nTPM]":"10.2","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"14.1","Tissue RNA - fallopian tube [nTPM]":"10.2","Tissue RNA - gallbladder [nTPM]":"8.5","Tissue RNA - heart muscle [nTPM]":"90.5","Tissue RNA - hippocampal formation [nTPM]":"12.3","Tissue RNA - hypothalamus [nTPM]":"13.8","Tissue RNA - kidney [nTPM]":"51.9","Tissue RNA - liver [nTPM]":"245.5","Tissue RNA - lung [nTPM]":"13.4","Tissue RNA - lymph node [nTPM]":"6.4","Tissue RNA - medulla oblongata [nTPM]":"14.6","Tissue RNA - midbrain [nTPM]":"14.2","Tissue RNA - ovary [nTPM]":"8.6","Tissue RNA - pancreas [nTPM]":"33.1","Tissue RNA - parathyroid gland [nTPM]":"4.7","Tissue RNA - pituitary gland [nTPM]":"9.2","Tissue RNA - placenta [nTPM]":"7.5","Tissue RNA - pons [nTPM]":"13.1","Tissue RNA - prostate [nTPM]":"13.9","Tissue RNA - rectum [nTPM]":"21.3","Tissue RNA - retina [nTPM]":"0.9","Tissue RNA - salivary gland [nTPM]":"19.2","Tissue RNA - seminal vesicle [nTPM]":"7.2","Tissue RNA - skeletal muscle [nTPM]":"158.2","Tissue RNA - skin 1 [nTPM]":"13.7","Tissue RNA - small intestine [nTPM]":"73.2","Tissue RNA - smooth muscle [nTPM]":"5.8","Tissue RNA - spinal cord [nTPM]":"14.0","Tissue RNA - spleen [nTPM]":"31.6","Tissue RNA - stomach 1 [nTPM]":"34.5","Tissue RNA - testis [nTPM]":"20.3","Tissue RNA - thalamus [nTPM]":"16.0","Tissue RNA - thymus [nTPM]":"6.6","Tissue RNA - thyroid gland [nTPM]":"21.9","Tissue RNA - tongue [nTPM]":"79.7","Tissue RNA - tonsil [nTPM]":"3.4","Tissue RNA - urinary bladder [nTPM]":"18.0","Tissue RNA - vagina [nTPM]":"12.7","Tissue RNA - white matter [nTPM]":"14.8","Cell RNA - A-431 [nTPM]":"3.2","Cell RNA - A549 [nTPM]":"11.4","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"9.7","Cell RNA - ASC diff [nTPM]":"12.9","Cell RNA - ASC TERT1 [nTPM]":"5.1","Cell RNA - BEWO [nTPM]":"11.1","Cell RNA - BJ [nTPM]":"4.7","Cell RNA - BJ hTERT+ [nTPM]":"4.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.5","Cell RNA - CACO-2 [nTPM]":"8.9","Cell RNA - CAPAN-2 [nTPM]":"8.0","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"11.9","Cell RNA - fHDF\/TERT166 [nTPM]":"3.9","Cell RNA - GAMG [nTPM]":"2.7","Cell RNA - HaCaT [nTPM]":"5.2","Cell RNA - HAP1 [nTPM]":"6.6","Cell RNA - HBEC3-KT [nTPM]":"2.1","Cell RNA - HBF TERT88 [nTPM]":"0.8","Cell RNA - HDLM-2 [nTPM]":"16.7","Cell RNA - HEK 293 [nTPM]":"8.2","Cell RNA - HEL [nTPM]":"8.2","Cell RNA - HeLa [nTPM]":"3.6","Cell RNA - Hep G2 [nTPM]":"19.3","Cell RNA - HHSteC [nTPM]":"9.3","Cell RNA - HL-60 [nTPM]":"0.7","Cell RNA - HMC-1 [nTPM]":"36.0","Cell RNA - HSkMC [nTPM]":"15.4","Cell RNA - hTCEpi [nTPM]":"3.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.6","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"1.8","Cell RNA - HUVEC TERT2 [nTPM]":"6.1","Cell RNA - JURKAT [nTPM]":"20.6","Cell RNA - K-562 [nTPM]":"6.9","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"2.7","Cell RNA - MCF7 [nTPM]":"6.8","Cell RNA - MOLT-4 [nTPM]":"11.7","Cell RNA - NB-4 [nTPM]":"19.2","Cell RNA - NTERA-2 [nTPM]":"2.0","Cell RNA - OE19 [nTPM]":"10.6","Cell RNA - PC-3 [nTPM]":"4.6","Cell RNA - REH [nTPM]":"8.6","Cell RNA - RH-30 [nTPM]":"4.2","Cell RNA - RPMI-8226 [nTPM]":"2.2","Cell RNA - RPTEC TERT1 [nTPM]":"11.3","Cell RNA - RT4 [nTPM]":"18.2","Cell RNA - SCLC-21H [nTPM]":"1.1","Cell RNA - SH-SY5Y [nTPM]":"6.0","Cell RNA - SiHa [nTPM]":"9.7","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"15.8","Cell RNA - SuSa [nTPM]":"0.9","Cell RNA - T-47d [nTPM]":"7.7","Cell RNA - THP-1 [nTPM]":"13.1","Cell RNA - TIME [nTPM]":"6.9","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"4.7","Cell RNA - U-2197 [nTPM]":"4.5","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"15.3","Cell RNA - U-266\/84 [nTPM]":"9.3","Cell RNA - U-698 [nTPM]":"4.1","Cell RNA - U-87 MG [nTPM]":"10.2","Cell RNA - U-937 [nTPM]":"7.0","Cell RNA - WM-115 [nTPM]":"4.1","Blood RNA - basophil [nTPM]":"8.3","Blood RNA - classical monocyte [nTPM]":"15.3","Blood RNA - eosinophil [nTPM]":"7.5","Blood RNA - gdT-cell [nTPM]":"13.7","Blood RNA - intermediate monocyte [nTPM]":"16.3","Blood RNA - MAIT T-cell [nTPM]":"9.3","Blood RNA - memory B-cell [nTPM]":"6.3","Blood RNA - memory CD4 T-cell [nTPM]":"12.2","Blood RNA - memory CD8 T-cell [nTPM]":"14.2","Blood RNA - myeloid DC [nTPM]":"13.2","Blood RNA - naive B-cell [nTPM]":"8.9","Blood RNA - naive CD4 T-cell [nTPM]":"15.3","Blood RNA - naive CD8 T-cell [nTPM]":"14.4","Blood RNA - neutrophil [nTPM]":"1.4","Blood RNA - NK-cell [nTPM]":"19.9","Blood RNA - non-classical monocyte [nTPM]":"10.2","Blood RNA - plasmacytoid DC [nTPM]":"11.0","Blood RNA - T-reg [nTPM]":"14.7","Blood RNA - total PBMC [nTPM]":"12.8","Brain RNA - amygdala [nTPM]":"13.3","Brain RNA - basal ganglia [nTPM]":"15.4","Brain RNA - cerebellum [nTPM]":"13.6","Brain RNA - cerebral cortex [nTPM]":"16.6","Brain RNA - hippocampal formation [nTPM]":"12.3","Brain RNA - hypothalamus [nTPM]":"13.8","Brain RNA - medulla oblongata [nTPM]":"14.6","Brain RNA - midbrain [nTPM]":"14.2","Brain RNA - pons [nTPM]":"13.1","Brain RNA - spinal cord [nTPM]":"14.0","Brain RNA - thalamus [nTPM]":"16.0","Brain RNA - white matter [nTPM]":"14.8","Single Cell Type RNA - Adipocytes [nTPM]":"18.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.7","Single Cell Type RNA - Astrocytes [nTPM]":"10.1","Single Cell Type RNA - B-cells [nTPM]":"6.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"44.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"13.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"78.8","Single Cell Type RNA - dendritic cells [nTPM]":"9.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"303.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"50.9","Single Cell Type RNA - Ductal cells [nTPM]":"35.2","Single Cell Type RNA - Early spermatids [nTPM]":"23.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.2","Single Cell Type RNA - Endothelial cells [nTPM]":"13.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"45.6","Single Cell Type RNA - Erythroid cells [nTPM]":"38.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"32.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"31.3","Single Cell Type RNA - Fibroblasts [nTPM]":"18.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"28.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.8","Single Cell Type RNA - granulocytes [nTPM]":"19.1","Single Cell Type RNA - Granulosa cells [nTPM]":"12.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.2","Single Cell Type RNA - Hepatocytes [nTPM]":"203.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"55.1","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"105.3","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"21.0","Single Cell Type RNA - Langerhans cells [nTPM]":"8.9","Single Cell Type RNA - Late spermatids [nTPM]":"36.5","Single Cell Type RNA - Leydig cells [nTPM]":"21.5","Single Cell Type RNA - Macrophages [nTPM]":"15.3","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"26.1","Single Cell Type RNA - Muller glia cells [nTPM]":"13.6","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"26.7","Single Cell Type RNA - Paneth cells [nTPM]":"185.7","Single Cell Type RNA - Peritubular cells [nTPM]":"18.0","Single Cell Type RNA - Plasma cells [nTPM]":"7.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"435.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"94.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.7","Single Cell Type RNA - Spermatocytes [nTPM]":"41.5","Single Cell Type RNA - Spermatogonia [nTPM]":"8.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"75.5","Single Cell Type RNA - T-cells [nTPM]":"11.9","Single Cell Type RNA - Theca cells [nTPM]":"140.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"185.9","Single Cell Type RNA - Urothelial cells [nTPM]":"12.7"},{"Gene":"ACADSB","Gene synonym":["ACAD7","SBCAD"],"Ensembl":"ENSG00000196177","Gene description":"Acyl-CoA dehydrogenase short\/branched chain","Uniprot":["P45954"],"Chromosome":"10","Position":"123008979-123058290","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"360.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"499.5","Proximal tubular cells":"137.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"32.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"54.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041458","HPA063555"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"37000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA041458":"AB_2677491","HPA063555":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.40e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.37e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.37e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-2"},"Tissue RNA - adipose tissue [nTPM]":"14.8","Tissue RNA - adrenal gland [nTPM]":"27.4","Tissue RNA - amygdala [nTPM]":"8.0","Tissue RNA - appendix [nTPM]":"7.1","Tissue RNA - basal ganglia [nTPM]":"8.5","Tissue RNA - bone marrow [nTPM]":"3.8","Tissue RNA - breast [nTPM]":"23.9","Tissue RNA - cerebellum [nTPM]":"13.9","Tissue RNA - cerebral cortex [nTPM]":"10.3","Tissue RNA - cervix [nTPM]":"7.8","Tissue RNA - choroid plexus [nTPM]":"13.1","Tissue RNA - colon [nTPM]":"15.9","Tissue RNA - duodenum [nTPM]":"52.4","Tissue RNA - endometrium 1 [nTPM]":"9.9","Tissue RNA - epididymis [nTPM]":"7.7","Tissue RNA - esophagus [nTPM]":"12.6","Tissue RNA - fallopian tube [nTPM]":"9.7","Tissue RNA - gallbladder [nTPM]":"7.6","Tissue RNA - heart muscle [nTPM]":"38.5","Tissue RNA - hippocampal formation [nTPM]":"8.6","Tissue RNA - hypothalamus [nTPM]":"6.7","Tissue RNA - kidney [nTPM]":"90.2","Tissue RNA - liver [nTPM]":"360.1","Tissue RNA - lung [nTPM]":"12.7","Tissue RNA - lymph node [nTPM]":"8.2","Tissue RNA - medulla oblongata [nTPM]":"6.3","Tissue RNA - midbrain [nTPM]":"7.6","Tissue RNA - ovary [nTPM]":"12.8","Tissue RNA - pancreas [nTPM]":"15.8","Tissue RNA - parathyroid gland [nTPM]":"33.4","Tissue RNA - pituitary gland [nTPM]":"8.8","Tissue RNA - placenta [nTPM]":"5.1","Tissue RNA - pons [nTPM]":"6.8","Tissue RNA - prostate [nTPM]":"22.7","Tissue RNA - rectum [nTPM]":"16.8","Tissue RNA - retina [nTPM]":"12.4","Tissue RNA - salivary gland [nTPM]":"15.7","Tissue RNA - seminal vesicle [nTPM]":"11.2","Tissue RNA - skeletal muscle [nTPM]":"42.4","Tissue RNA - skin 1 [nTPM]":"9.8","Tissue RNA - small intestine [nTPM]":"11.0","Tissue RNA - smooth muscle [nTPM]":"8.5","Tissue RNA - spinal cord [nTPM]":"5.9","Tissue RNA - spleen [nTPM]":"6.4","Tissue RNA - stomach 1 [nTPM]":"14.0","Tissue RNA - testis [nTPM]":"8.4","Tissue RNA - thalamus [nTPM]":"8.0","Tissue RNA - thymus [nTPM]":"7.4","Tissue RNA - thyroid gland [nTPM]":"12.3","Tissue RNA - tongue [nTPM]":"69.1","Tissue RNA - tonsil [nTPM]":"10.3","Tissue RNA - urinary bladder [nTPM]":"10.8","Tissue RNA - vagina [nTPM]":"8.1","Tissue RNA - white matter [nTPM]":"8.4","Cell RNA - A-431 [nTPM]":"15.4","Cell RNA - A549 [nTPM]":"10.9","Cell RNA - AF22 [nTPM]":"7.9","Cell RNA - AN3-CA [nTPM]":"14.5","Cell RNA - ASC diff [nTPM]":"10.6","Cell RNA - ASC TERT1 [nTPM]":"13.1","Cell RNA - BEWO [nTPM]":"7.0","Cell RNA - BJ [nTPM]":"9.3","Cell RNA - BJ hTERT+ [nTPM]":"18.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.1","Cell RNA - CACO-2 [nTPM]":"9.6","Cell RNA - CAPAN-2 [nTPM]":"4.9","Cell RNA - Daudi [nTPM]":"16.0","Cell RNA - EFO-21 [nTPM]":"6.3","Cell RNA - fHDF\/TERT166 [nTPM]":"7.9","Cell RNA - GAMG [nTPM]":"5.6","Cell RNA - HaCaT [nTPM]":"6.3","Cell RNA - HAP1 [nTPM]":"12.5","Cell RNA - HBEC3-KT [nTPM]":"6.5","Cell RNA - HBF TERT88 [nTPM]":"15.1","Cell RNA - HDLM-2 [nTPM]":"10.6","Cell RNA - HEK 293 [nTPM]":"12.9","Cell RNA - HEL [nTPM]":"8.3","Cell RNA - HeLa [nTPM]":"3.3","Cell RNA - Hep G2 [nTPM]":"54.8","Cell RNA - HHSteC [nTPM]":"7.5","Cell RNA - HL-60 [nTPM]":"12.0","Cell RNA - HMC-1 [nTPM]":"7.6","Cell RNA - HSkMC [nTPM]":"9.7","Cell RNA - hTCEpi [nTPM]":"6.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.8","Cell RNA - hTERT-HME1 [nTPM]":"5.3","Cell RNA - hTERT-RPE1 [nTPM]":"13.5","Cell RNA - HUVEC TERT2 [nTPM]":"9.0","Cell RNA - JURKAT [nTPM]":"13.2","Cell RNA - K-562 [nTPM]":"8.1","Cell RNA - Karpas-707 [nTPM]":"11.5","Cell RNA - LHCN-M2 [nTPM]":"11.5","Cell RNA - MCF7 [nTPM]":"7.1","Cell RNA - MOLT-4 [nTPM]":"11.4","Cell RNA - NB-4 [nTPM]":"9.8","Cell RNA - NTERA-2 [nTPM]":"4.8","Cell RNA - OE19 [nTPM]":"8.5","Cell RNA - PC-3 [nTPM]":"6.7","Cell RNA - REH [nTPM]":"13.4","Cell RNA - RH-30 [nTPM]":"16.6","Cell RNA - RPMI-8226 [nTPM]":"5.1","Cell RNA - RPTEC TERT1 [nTPM]":"13.1","Cell RNA - RT4 [nTPM]":"16.9","Cell RNA - SCLC-21H [nTPM]":"1.4","Cell RNA - SH-SY5Y [nTPM]":"9.1","Cell RNA - SiHa [nTPM]":"14.3","Cell RNA - SK-BR-3 [nTPM]":"4.2","Cell RNA - SK-MEL-30 [nTPM]":"14.4","Cell RNA - SuSa [nTPM]":"7.5","Cell RNA - T-47d [nTPM]":"12.9","Cell RNA - THP-1 [nTPM]":"5.8","Cell RNA - TIME [nTPM]":"9.5","Cell RNA - U-138 MG [nTPM]":"4.9","Cell RNA - U-2 OS [nTPM]":"4.4","Cell RNA - U-2197 [nTPM]":"11.4","Cell RNA - U-251 MG [nTPM]":"11.4","Cell RNA - U-266\/70 [nTPM]":"12.9","Cell RNA - U-266\/84 [nTPM]":"15.5","Cell RNA - U-698 [nTPM]":"8.5","Cell RNA - U-87 MG [nTPM]":"7.6","Cell RNA - U-937 [nTPM]":"11.1","Cell RNA - WM-115 [nTPM]":"3.8","Blood RNA - basophil [nTPM]":"17.4","Blood RNA - classical monocyte [nTPM]":"4.5","Blood RNA - eosinophil [nTPM]":"11.8","Blood RNA - gdT-cell [nTPM]":"8.8","Blood RNA - intermediate monocyte [nTPM]":"4.7","Blood RNA - MAIT T-cell [nTPM]":"10.2","Blood RNA - memory B-cell [nTPM]":"5.5","Blood RNA - memory CD4 T-cell [nTPM]":"8.1","Blood RNA - memory CD8 T-cell [nTPM]":"7.6","Blood RNA - myeloid DC [nTPM]":"6.4","Blood RNA - naive B-cell [nTPM]":"5.7","Blood RNA - naive CD4 T-cell [nTPM]":"7.4","Blood RNA - naive CD8 T-cell [nTPM]":"8.3","Blood RNA - neutrophil [nTPM]":"2.9","Blood RNA - NK-cell [nTPM]":"8.5","Blood RNA - non-classical monocyte [nTPM]":"2.9","Blood RNA - plasmacytoid DC [nTPM]":"3.8","Blood RNA - T-reg [nTPM]":"7.1","Blood RNA - total PBMC [nTPM]":"5.7","Brain RNA - amygdala [nTPM]":"8.0","Brain RNA - basal ganglia [nTPM]":"8.5","Brain RNA - cerebellum [nTPM]":"13.9","Brain RNA - cerebral cortex [nTPM]":"10.3","Brain RNA - hippocampal formation [nTPM]":"8.6","Brain RNA - hypothalamus [nTPM]":"6.7","Brain RNA - medulla oblongata [nTPM]":"6.3","Brain RNA - midbrain [nTPM]":"7.6","Brain RNA - pons [nTPM]":"6.8","Brain RNA - spinal cord [nTPM]":"5.9","Brain RNA - thalamus [nTPM]":"8.0","Brain RNA - white matter [nTPM]":"8.4","Single Cell Type RNA - Adipocytes [nTPM]":"7.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"53.1","Single Cell Type RNA - Astrocytes [nTPM]":"29.4","Single Cell Type RNA - B-cells [nTPM]":"11.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"17.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"58.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"27.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"80.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"37.1","Single Cell Type RNA - Club cells [nTPM]":"21.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.1","Single Cell Type RNA - dendritic cells [nTPM]":"8.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"46.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.3","Single Cell Type RNA - Early spermatids [nTPM]":"7.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.1","Single Cell Type RNA - Endothelial cells [nTPM]":"8.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.1","Single Cell Type RNA - Erythroid cells [nTPM]":"21.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"39.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.5","Single Cell Type RNA - Fibroblasts [nTPM]":"10.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.8","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"29.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.4","Single Cell Type RNA - Hepatocytes [nTPM]":"499.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.3","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"49.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.7","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"17.4","Single Cell Type RNA - Langerhans cells [nTPM]":"5.9","Single Cell Type RNA - Late spermatids [nTPM]":"8.1","Single Cell Type RNA - Leydig cells [nTPM]":"13.4","Single Cell Type RNA - Macrophages [nTPM]":"7.1","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"7.9","Single Cell Type RNA - Muller glia cells [nTPM]":"12.0","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"38.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.6","Single Cell Type RNA - Paneth cells [nTPM]":"13.1","Single Cell Type RNA - Peritubular cells [nTPM]":"10.9","Single Cell Type RNA - Plasma cells [nTPM]":"9.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"137.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.7","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.0","Single Cell Type RNA - Spermatocytes [nTPM]":"8.5","Single Cell Type RNA - Spermatogonia [nTPM]":"3.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"30.1","Single Cell Type RNA - T-cells [nTPM]":"13.3","Single Cell Type RNA - Theca cells [nTPM]":"18.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.3","Single Cell Type RNA - Urothelial cells [nTPM]":"12.0"},{"Gene":"ACADVL","Gene synonym":["ACAD6","LCACD","VLCAD"],"Ensembl":"ENSG00000072778","Gene description":"Acyl-CoA dehydrogenase very long chain","Uniprot":["P49748"],"Chromosome":"17","Position":"7217125-7225266","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Cardiomyopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"850.4"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019006","HPA020595"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"98000","Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm","Nucleoli"],"Antibody RRID":{"HPA019006":"AB_1844478","HPA020595":"AB_1844479"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.87e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-3"},"Tissue RNA - adipose tissue [nTPM]":"197.9","Tissue RNA - adrenal gland [nTPM]":"405.2","Tissue RNA - amygdala [nTPM]":"120.1","Tissue RNA - appendix [nTPM]":"78.7","Tissue RNA - basal ganglia [nTPM]":"131.0","Tissue RNA - bone marrow [nTPM]":"103.5","Tissue RNA - breast [nTPM]":"142.9","Tissue RNA - cerebellum [nTPM]":"128.4","Tissue RNA - cerebral cortex [nTPM]":"126.7","Tissue RNA - cervix [nTPM]":"110.5","Tissue RNA - choroid plexus [nTPM]":"170.6","Tissue RNA - colon [nTPM]":"157.3","Tissue RNA - duodenum [nTPM]":"306.2","Tissue RNA - endometrium 1 [nTPM]":"98.5","Tissue RNA - epididymis [nTPM]":"44.4","Tissue RNA - esophagus [nTPM]":"181.0","Tissue RNA - fallopian tube [nTPM]":"94.0","Tissue RNA - gallbladder [nTPM]":"92.6","Tissue RNA - heart muscle [nTPM]":"576.8","Tissue RNA - hippocampal formation [nTPM]":"117.8","Tissue RNA - hypothalamus [nTPM]":"125.0","Tissue RNA - kidney [nTPM]":"215.3","Tissue RNA - liver [nTPM]":"517.4","Tissue RNA - lung [nTPM]":"106.7","Tissue RNA - lymph node [nTPM]":"52.0","Tissue RNA - medulla oblongata [nTPM]":"127.5","Tissue RNA - midbrain [nTPM]":"125.3","Tissue RNA - ovary [nTPM]":"80.9","Tissue RNA - pancreas [nTPM]":"236.5","Tissue RNA - parathyroid gland [nTPM]":"159.6","Tissue RNA - pituitary gland [nTPM]":"189.6","Tissue RNA - placenta [nTPM]":"112.0","Tissue RNA - pons [nTPM]":"124.8","Tissue RNA - prostate [nTPM]":"133.2","Tissue RNA - rectum [nTPM]":"131.6","Tissue RNA - retina [nTPM]":"34.9","Tissue RNA - salivary gland [nTPM]":"158.5","Tissue RNA - seminal vesicle [nTPM]":"113.9","Tissue RNA - skeletal muscle [nTPM]":"850.4","Tissue RNA - skin 1 [nTPM]":"135.7","Tissue RNA - small intestine [nTPM]":"270.6","Tissue RNA - smooth muscle [nTPM]":"110.6","Tissue RNA - spinal cord [nTPM]":"118.2","Tissue RNA - spleen [nTPM]":"132.2","Tissue RNA - stomach 1 [nTPM]":"186.4","Tissue RNA - testis [nTPM]":"75.9","Tissue RNA - thalamus [nTPM]":"132.0","Tissue RNA - thymus [nTPM]":"83.4","Tissue RNA - thyroid gland [nTPM]":"159.3","Tissue RNA - tongue [nTPM]":"817.1","Tissue RNA - tonsil [nTPM]":"82.9","Tissue RNA - urinary bladder [nTPM]":"137.1","Tissue RNA - vagina [nTPM]":"115.3","Tissue RNA - white matter [nTPM]":"122.7","Cell RNA - A-431 [nTPM]":"193.7","Cell RNA - A549 [nTPM]":"162.5","Cell RNA - AF22 [nTPM]":"65.8","Cell RNA - AN3-CA [nTPM]":"92.4","Cell RNA - ASC diff [nTPM]":"271.2","Cell RNA - ASC TERT1 [nTPM]":"99.2","Cell RNA - BEWO [nTPM]":"135.9","Cell RNA - BJ [nTPM]":"156.5","Cell RNA - BJ hTERT+ [nTPM]":"169.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"136.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"84.5","Cell RNA - CACO-2 [nTPM]":"67.2","Cell RNA - CAPAN-2 [nTPM]":"155.3","Cell RNA - Daudi [nTPM]":"90.4","Cell RNA - EFO-21 [nTPM]":"109.0","Cell RNA - fHDF\/TERT166 [nTPM]":"260.0","Cell RNA - GAMG [nTPM]":"49.7","Cell RNA - HaCaT [nTPM]":"147.9","Cell RNA - HAP1 [nTPM]":"43.8","Cell RNA - HBEC3-KT [nTPM]":"135.5","Cell RNA - HBF TERT88 [nTPM]":"119.6","Cell RNA - HDLM-2 [nTPM]":"295.9","Cell RNA - HEK 293 [nTPM]":"47.1","Cell RNA - HEL [nTPM]":"50.6","Cell RNA - HeLa [nTPM]":"120.9","Cell RNA - Hep G2 [nTPM]":"101.1","Cell RNA - HHSteC [nTPM]":"131.2","Cell RNA - HL-60 [nTPM]":"49.0","Cell RNA - HMC-1 [nTPM]":"129.5","Cell RNA - HSkMC [nTPM]":"112.5","Cell RNA - hTCEpi [nTPM]":"122.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"114.7","Cell RNA - hTERT-HME1 [nTPM]":"178.5","Cell RNA - hTERT-RPE1 [nTPM]":"212.6","Cell RNA - HUVEC TERT2 [nTPM]":"124.8","Cell RNA - JURKAT [nTPM]":"111.3","Cell RNA - K-562 [nTPM]":"73.3","Cell RNA - Karpas-707 [nTPM]":"110.2","Cell RNA - LHCN-M2 [nTPM]":"222.7","Cell RNA - MCF7 [nTPM]":"65.3","Cell RNA - MOLT-4 [nTPM]":"49.6","Cell RNA - NB-4 [nTPM]":"68.4","Cell RNA - NTERA-2 [nTPM]":"34.3","Cell RNA - OE19 [nTPM]":"178.4","Cell RNA - PC-3 [nTPM]":"91.9","Cell RNA - REH [nTPM]":"70.4","Cell RNA - RH-30 [nTPM]":"78.3","Cell RNA - RPMI-8226 [nTPM]":"227.2","Cell RNA - RPTEC TERT1 [nTPM]":"305.1","Cell RNA - RT4 [nTPM]":"155.0","Cell RNA - SCLC-21H [nTPM]":"19.1","Cell RNA - SH-SY5Y [nTPM]":"47.3","Cell RNA - SiHa [nTPM]":"206.8","Cell RNA - SK-BR-3 [nTPM]":"224.8","Cell RNA - SK-MEL-30 [nTPM]":"110.8","Cell RNA - SuSa [nTPM]":"60.6","Cell RNA - T-47d [nTPM]":"102.8","Cell RNA - THP-1 [nTPM]":"74.9","Cell RNA - TIME [nTPM]":"151.5","Cell RNA - U-138 MG [nTPM]":"127.5","Cell RNA - U-2 OS [nTPM]":"101.6","Cell RNA - U-2197 [nTPM]":"75.9","Cell RNA - U-251 MG [nTPM]":"149.9","Cell RNA - U-266\/70 [nTPM]":"104.5","Cell RNA - U-266\/84 [nTPM]":"59.1","Cell RNA - U-698 [nTPM]":"5.2","Cell RNA - U-87 MG [nTPM]":"230.7","Cell RNA - U-937 [nTPM]":"85.7","Cell RNA - WM-115 [nTPM]":"94.9","Blood RNA - basophil [nTPM]":"24.2","Blood RNA - classical monocyte [nTPM]":"96.1","Blood RNA - eosinophil [nTPM]":"121.3","Blood RNA - gdT-cell [nTPM]":"39.1","Blood RNA - intermediate monocyte [nTPM]":"57.8","Blood RNA - MAIT T-cell [nTPM]":"35.7","Blood RNA - memory B-cell [nTPM]":"25.2","Blood RNA - memory CD4 T-cell [nTPM]":"32.5","Blood RNA - memory CD8 T-cell [nTPM]":"43.8","Blood RNA - myeloid DC [nTPM]":"99.9","Blood RNA - naive B-cell [nTPM]":"24.6","Blood RNA - naive CD4 T-cell [nTPM]":"23.7","Blood RNA - naive CD8 T-cell [nTPM]":"29.1","Blood RNA - neutrophil [nTPM]":"20.2","Blood RNA - NK-cell [nTPM]":"37.8","Blood RNA - non-classical monocyte [nTPM]":"39.3","Blood RNA - plasmacytoid DC [nTPM]":"80.4","Blood RNA - T-reg [nTPM]":"31.8","Blood RNA - total PBMC [nTPM]":"79.4","Brain RNA - amygdala [nTPM]":"120.1","Brain RNA - basal ganglia [nTPM]":"131.0","Brain RNA - cerebellum [nTPM]":"128.4","Brain RNA - cerebral cortex [nTPM]":"126.7","Brain RNA - hippocampal formation [nTPM]":"117.8","Brain RNA - hypothalamus [nTPM]":"125.0","Brain RNA - medulla oblongata [nTPM]":"127.5","Brain RNA - midbrain [nTPM]":"125.3","Brain RNA - pons [nTPM]":"124.8","Brain RNA - spinal cord [nTPM]":"118.2","Brain RNA - thalamus [nTPM]":"132.0","Brain RNA - white matter [nTPM]":"122.7","Single Cell Type RNA - Adipocytes [nTPM]":"109.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"81.9","Single Cell Type RNA - Astrocytes [nTPM]":"143.3","Single Cell Type RNA - B-cells [nTPM]":"72.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"87.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"336.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"322.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"91.6","Single Cell Type RNA - Bipolar cells [nTPM]":"42.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"157.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"104.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"451.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"138.7","Single Cell Type RNA - Club cells [nTPM]":"206.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"202.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"62.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"482.9","Single Cell Type RNA - dendritic cells [nTPM]":"87.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"484.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"185.9","Single Cell Type RNA - Ductal cells [nTPM]":"310.8","Single Cell Type RNA - Early spermatids [nTPM]":"133.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"87.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"52.7","Single Cell Type RNA - Endothelial cells [nTPM]":"77.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"179.3","Single Cell Type RNA - Erythroid cells [nTPM]":"65.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"40.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"77.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"197.8","Single Cell Type RNA - Fibroblasts [nTPM]":"118.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"406.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"88.5","Single Cell Type RNA - granulocytes [nTPM]":"88.4","Single Cell Type RNA - Granulosa cells [nTPM]":"121.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"53.6","Single Cell Type RNA - Hepatocytes [nTPM]":"365.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"182.4","Single Cell Type RNA - Horizontal cells [nTPM]":"33.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"33.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"251.8","Single Cell Type RNA - Ionocytes [nTPM]":"233.9","Single Cell Type RNA - Kupffer cells [nTPM]":"67.9","Single Cell Type RNA - Langerhans cells [nTPM]":"94.6","Single Cell Type RNA - Late spermatids [nTPM]":"249.9","Single Cell Type RNA - Leydig cells [nTPM]":"124.5","Single Cell Type RNA - Macrophages [nTPM]":"101.5","Single Cell Type RNA - Melanocytes [nTPM]":"81.8","Single Cell Type RNA - Microglial cells [nTPM]":"34.7","Single Cell Type RNA - monocytes [nTPM]":"274.9","Single Cell Type RNA - Muller glia cells [nTPM]":"40.7","Single Cell Type RNA - NK-cells [nTPM]":"73.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"23.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"24.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"106.1","Single Cell Type RNA - Paneth cells [nTPM]":"388.9","Single Cell Type RNA - Peritubular cells [nTPM]":"132.8","Single Cell Type RNA - Plasma cells [nTPM]":"172.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"369.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"489.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"345.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"144.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"41.3","Single Cell Type RNA - Sertoli cells [nTPM]":"105.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"88.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"147.4","Single Cell Type RNA - Spermatocytes [nTPM]":"114.3","Single Cell Type RNA - Spermatogonia [nTPM]":"47.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"113.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"87.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"663.3","Single Cell Type RNA - T-cells [nTPM]":"75.5","Single Cell Type RNA - Theca cells [nTPM]":"169.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"316.8","Single Cell Type RNA - Urothelial cells [nTPM]":"367.5"},{"Gene":"ACAT1","Gene synonym":["ACAT","THIL"],"Ensembl":"ENSG00000075239","Gene description":"Acetyl-CoA acetyltransferase 1","Uniprot":["P24752"],"Chromosome":"11","Position":"108116695-108147603","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"622.7","liver":"969.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"508.4","Distal tubular cells":"698.5","Hepatocytes":"663.4","Proximal tubular cells":"1484.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RPMI-8226":"420.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004428","HPA007569"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1400000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA004428":"AB_1078088","HPA007569":"AB_1844482"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.43e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-3"},"Tissue RNA - adipose tissue [nTPM]":"135.4","Tissue RNA - adrenal gland [nTPM]":"151.3","Tissue RNA - amygdala [nTPM]":"45.2","Tissue RNA - appendix [nTPM]":"24.3","Tissue RNA - basal ganglia [nTPM]":"45.3","Tissue RNA - bone marrow [nTPM]":"38.4","Tissue RNA - breast [nTPM]":"56.9","Tissue RNA - cerebellum [nTPM]":"47.1","Tissue RNA - cerebral cortex [nTPM]":"60.1","Tissue RNA - cervix [nTPM]":"41.0","Tissue RNA - choroid plexus [nTPM]":"91.8","Tissue RNA - colon [nTPM]":"96.3","Tissue RNA - duodenum [nTPM]":"103.9","Tissue RNA - endometrium 1 [nTPM]":"44.0","Tissue RNA - epididymis [nTPM]":"34.1","Tissue RNA - esophagus [nTPM]":"45.0","Tissue RNA - fallopian tube [nTPM]":"39.1","Tissue RNA - gallbladder [nTPM]":"25.6","Tissue RNA - heart muscle [nTPM]":"289.4","Tissue RNA - hippocampal formation [nTPM]":"42.7","Tissue RNA - hypothalamus [nTPM]":"46.8","Tissue RNA - kidney [nTPM]":"622.7","Tissue RNA - liver [nTPM]":"969.5","Tissue RNA - lung [nTPM]":"43.7","Tissue RNA - lymph node [nTPM]":"28.2","Tissue RNA - medulla oblongata [nTPM]":"44.8","Tissue RNA - midbrain [nTPM]":"45.2","Tissue RNA - ovary [nTPM]":"64.7","Tissue RNA - pancreas [nTPM]":"110.6","Tissue RNA - parathyroid gland [nTPM]":"95.9","Tissue RNA - pituitary gland [nTPM]":"30.9","Tissue RNA - placenta [nTPM]":"24.7","Tissue RNA - pons [nTPM]":"45.2","Tissue RNA - prostate [nTPM]":"45.6","Tissue RNA - rectum [nTPM]":"85.6","Tissue RNA - retina [nTPM]":"26.2","Tissue RNA - salivary gland [nTPM]":"104.1","Tissue RNA - seminal vesicle [nTPM]":"60.2","Tissue RNA - skeletal muscle [nTPM]":"461.1","Tissue RNA - skin 1 [nTPM]":"45.3","Tissue RNA - small intestine [nTPM]":"53.2","Tissue RNA - smooth muscle [nTPM]":"57.1","Tissue RNA - spinal cord [nTPM]":"46.7","Tissue RNA - spleen [nTPM]":"29.3","Tissue RNA - stomach 1 [nTPM]":"81.9","Tissue RNA - testis [nTPM]":"66.3","Tissue RNA - thalamus [nTPM]":"45.6","Tissue RNA - thymus [nTPM]":"19.1","Tissue RNA - thyroid gland [nTPM]":"65.5","Tissue RNA - tongue [nTPM]":"410.8","Tissue RNA - tonsil [nTPM]":"29.7","Tissue RNA - urinary bladder [nTPM]":"44.1","Tissue RNA - vagina [nTPM]":"34.6","Tissue RNA - white matter [nTPM]":"47.7","Cell RNA - A-431 [nTPM]":"76.9","Cell RNA - A549 [nTPM]":"57.7","Cell RNA - AF22 [nTPM]":"48.2","Cell RNA - AN3-CA [nTPM]":"139.3","Cell RNA - ASC diff [nTPM]":"155.9","Cell RNA - ASC TERT1 [nTPM]":"138.7","Cell RNA - BEWO [nTPM]":"25.1","Cell RNA - BJ [nTPM]":"71.7","Cell RNA - BJ hTERT+ [nTPM]":"78.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"77.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"91.7","Cell RNA - CACO-2 [nTPM]":"168.1","Cell RNA - CAPAN-2 [nTPM]":"77.3","Cell RNA - Daudi [nTPM]":"41.3","Cell RNA - EFO-21 [nTPM]":"116.8","Cell RNA - fHDF\/TERT166 [nTPM]":"83.6","Cell RNA - GAMG [nTPM]":"119.7","Cell RNA - HaCaT [nTPM]":"78.1","Cell RNA - HAP1 [nTPM]":"142.3","Cell RNA - HBEC3-KT [nTPM]":"70.3","Cell RNA - HBF TERT88 [nTPM]":"83.3","Cell RNA - HDLM-2 [nTPM]":"84.9","Cell RNA - HEK 293 [nTPM]":"114.6","Cell RNA - HEL [nTPM]":"117.4","Cell RNA - HeLa [nTPM]":"64.6","Cell RNA - Hep G2 [nTPM]":"163.9","Cell RNA - HHSteC [nTPM]":"107.6","Cell RNA - HL-60 [nTPM]":"112.9","Cell RNA - HMC-1 [nTPM]":"64.9","Cell RNA - HSkMC [nTPM]":"124.6","Cell RNA - hTCEpi [nTPM]":"77.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"69.2","Cell RNA - hTERT-HME1 [nTPM]":"127.4","Cell RNA - hTERT-RPE1 [nTPM]":"91.5","Cell RNA - HUVEC TERT2 [nTPM]":"85.0","Cell RNA - JURKAT [nTPM]":"92.3","Cell RNA - K-562 [nTPM]":"172.1","Cell RNA - Karpas-707 [nTPM]":"61.8","Cell RNA - LHCN-M2 [nTPM]":"128.6","Cell RNA - MCF7 [nTPM]":"45.8","Cell RNA - MOLT-4 [nTPM]":"57.4","Cell RNA - NB-4 [nTPM]":"122.4","Cell RNA - NTERA-2 [nTPM]":"48.2","Cell RNA - OE19 [nTPM]":"103.1","Cell RNA - PC-3 [nTPM]":"135.0","Cell RNA - REH [nTPM]":"88.1","Cell RNA - RH-30 [nTPM]":"96.9","Cell RNA - RPMI-8226 [nTPM]":"420.4","Cell RNA - RPTEC TERT1 [nTPM]":"114.7","Cell RNA - RT4 [nTPM]":"50.4","Cell RNA - SCLC-21H [nTPM]":"75.7","Cell RNA - SH-SY5Y [nTPM]":"88.1","Cell RNA - SiHa [nTPM]":"111.6","Cell RNA - SK-BR-3 [nTPM]":"152.7","Cell RNA - SK-MEL-30 [nTPM]":"83.0","Cell RNA - SuSa [nTPM]":"37.0","Cell RNA - T-47d [nTPM]":"132.2","Cell RNA - THP-1 [nTPM]":"97.6","Cell RNA - TIME [nTPM]":"87.4","Cell RNA - U-138 MG [nTPM]":"83.2","Cell RNA - U-2 OS [nTPM]":"44.5","Cell RNA - U-2197 [nTPM]":"73.5","Cell RNA - U-251 MG [nTPM]":"88.8","Cell RNA - U-266\/70 [nTPM]":"18.9","Cell RNA - U-266\/84 [nTPM]":"57.8","Cell RNA - U-698 [nTPM]":"77.7","Cell RNA - U-87 MG [nTPM]":"37.6","Cell RNA - U-937 [nTPM]":"233.1","Cell RNA - WM-115 [nTPM]":"59.6","Blood RNA - basophil [nTPM]":"1.4","Blood RNA - classical monocyte [nTPM]":"17.1","Blood RNA - eosinophil [nTPM]":"4.7","Blood RNA - gdT-cell [nTPM]":"25.3","Blood RNA - intermediate monocyte [nTPM]":"25.5","Blood RNA - MAIT T-cell [nTPM]":"29.9","Blood RNA - memory B-cell [nTPM]":"29.2","Blood RNA - memory CD4 T-cell [nTPM]":"28.8","Blood RNA - memory CD8 T-cell [nTPM]":"30.0","Blood RNA - myeloid DC [nTPM]":"33.5","Blood RNA - naive B-cell [nTPM]":"13.8","Blood RNA - naive CD4 T-cell [nTPM]":"25.5","Blood RNA - naive CD8 T-cell [nTPM]":"22.4","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"13.4","Blood RNA - non-classical monocyte [nTPM]":"27.8","Blood RNA - plasmacytoid DC [nTPM]":"11.3","Blood RNA - T-reg [nTPM]":"35.7","Blood RNA - total PBMC [nTPM]":"23.4","Brain RNA - amygdala [nTPM]":"45.2","Brain RNA - basal ganglia [nTPM]":"45.3","Brain RNA - cerebellum [nTPM]":"47.1","Brain RNA - cerebral cortex [nTPM]":"60.1","Brain RNA - hippocampal formation [nTPM]":"42.7","Brain RNA - hypothalamus [nTPM]":"46.8","Brain RNA - medulla oblongata [nTPM]":"44.8","Brain RNA - midbrain [nTPM]":"45.2","Brain RNA - pons [nTPM]":"45.2","Brain RNA - spinal cord [nTPM]":"46.7","Brain RNA - thalamus [nTPM]":"45.6","Brain RNA - white matter [nTPM]":"47.7","Single Cell Type RNA - Adipocytes [nTPM]":"50.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"54.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"91.8","Single Cell Type RNA - Astrocytes [nTPM]":"17.9","Single Cell Type RNA - B-cells [nTPM]":"37.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"43.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"52.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"48.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.9","Single Cell Type RNA - Bipolar cells [nTPM]":"30.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"34.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"29.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"508.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"78.6","Single Cell Type RNA - Club cells [nTPM]":"33.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"104.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"39.9","Single Cell Type RNA - dendritic cells [nTPM]":"29.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"125.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"698.5","Single Cell Type RNA - Ductal cells [nTPM]":"43.1","Single Cell Type RNA - Early spermatids [nTPM]":"345.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"62.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"42.1","Single Cell Type RNA - Endothelial cells [nTPM]":"62.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"30.0","Single Cell Type RNA - Erythroid cells [nTPM]":"74.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"35.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"60.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"41.5","Single Cell Type RNA - Fibroblasts [nTPM]":"57.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"29.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.7","Single Cell Type RNA - granulocytes [nTPM]":"27.8","Single Cell Type RNA - Granulosa cells [nTPM]":"48.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"99.2","Single Cell Type RNA - Hepatocytes [nTPM]":"663.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"97.9","Single Cell Type RNA - Horizontal cells [nTPM]":"38.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"38.5","Single Cell Type RNA - Ionocytes [nTPM]":"97.6","Single Cell Type RNA - Kupffer cells [nTPM]":"73.6","Single Cell Type RNA - Langerhans cells [nTPM]":"27.8","Single Cell Type RNA - Late spermatids [nTPM]":"65.3","Single Cell Type RNA - Leydig cells [nTPM]":"66.5","Single Cell Type RNA - Macrophages [nTPM]":"39.1","Single Cell Type RNA - Melanocytes [nTPM]":"58.7","Single Cell Type RNA - Microglial cells [nTPM]":"30.0","Single Cell Type RNA - monocytes [nTPM]":"50.1","Single Cell Type RNA - Muller glia cells [nTPM]":"39.1","Single Cell Type RNA - NK-cells [nTPM]":"25.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"26.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"33.8","Single Cell Type RNA - Paneth cells [nTPM]":"93.8","Single Cell Type RNA - Peritubular cells [nTPM]":"82.4","Single Cell Type RNA - Plasma cells [nTPM]":"52.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"27.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"51.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1484.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"101.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"28.8","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"54.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"69.2","Single Cell Type RNA - Spermatocytes [nTPM]":"172.7","Single Cell Type RNA - Spermatogonia [nTPM]":"27.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"39.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"48.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"25.2","Single Cell Type RNA - T-cells [nTPM]":"38.1","Single Cell Type RNA - Theca cells [nTPM]":"61.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"84.5","Single Cell Type RNA - Urothelial cells [nTPM]":"24.4"},{"Gene":"ACBD5","Gene synonym":["DKFZp434A2417","KIAA1996"],"Ensembl":"ENSG00000107897","Gene description":"Acyl-CoA binding domain containing 5","Uniprot":["Q5T8D3"],"Chromosome":"10","Position":"27168135-27243046","Protein class":["Disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Autophagy","Transport"],"Molecular function":null,"Disease involvement":["Leukodystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011861","HPA012145"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Peroxisomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Peroxisomes"],"Subcellular additional location":null,"Antibody RRID":{"HPA011861":"AB_1844493","HPA012145":"AB_1844494"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.33e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.68e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.91e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-3"},"Tissue RNA - adipose tissue [nTPM]":"14.6","Tissue RNA - adrenal gland [nTPM]":"25.1","Tissue RNA - amygdala [nTPM]":"31.0","Tissue RNA - appendix [nTPM]":"13.5","Tissue RNA - basal ganglia [nTPM]":"37.0","Tissue RNA - bone marrow [nTPM]":"18.2","Tissue RNA - breast [nTPM]":"12.3","Tissue RNA - cerebellum [nTPM]":"36.2","Tissue RNA - cerebral cortex [nTPM]":"37.1","Tissue RNA - cervix [nTPM]":"13.2","Tissue RNA - choroid plexus [nTPM]":"24.2","Tissue RNA - colon [nTPM]":"20.3","Tissue RNA - duodenum [nTPM]":"39.8","Tissue RNA - endometrium 1 [nTPM]":"9.4","Tissue RNA - epididymis [nTPM]":"9.7","Tissue RNA - esophagus [nTPM]":"12.0","Tissue RNA - fallopian tube [nTPM]":"12.0","Tissue RNA - gallbladder [nTPM]":"15.4","Tissue RNA - heart muscle [nTPM]":"40.4","Tissue RNA - hippocampal formation [nTPM]":"27.6","Tissue RNA - hypothalamus [nTPM]":"33.1","Tissue RNA - kidney [nTPM]":"37.3","Tissue RNA - liver [nTPM]":"73.8","Tissue RNA - lung [nTPM]":"14.7","Tissue RNA - lymph node [nTPM]":"14.7","Tissue RNA - medulla oblongata [nTPM]":"37.2","Tissue RNA - midbrain [nTPM]":"34.0","Tissue RNA - ovary [nTPM]":"9.9","Tissue RNA - pancreas [nTPM]":"11.1","Tissue RNA - parathyroid gland [nTPM]":"31.2","Tissue RNA - pituitary gland [nTPM]":"6.4","Tissue RNA - placenta [nTPM]":"13.4","Tissue RNA - pons [nTPM]":"38.1","Tissue RNA - prostate [nTPM]":"15.2","Tissue RNA - rectum [nTPM]":"20.9","Tissue RNA - retina [nTPM]":"36.2","Tissue RNA - salivary gland [nTPM]":"10.3","Tissue RNA - seminal vesicle [nTPM]":"11.4","Tissue RNA - skeletal muscle [nTPM]":"31.0","Tissue RNA - skin 1 [nTPM]":"17.3","Tissue RNA - small intestine [nTPM]":"39.2","Tissue RNA - smooth muscle [nTPM]":"8.8","Tissue RNA - spinal cord [nTPM]":"36.7","Tissue RNA - spleen [nTPM]":"14.7","Tissue RNA - stomach 1 [nTPM]":"21.0","Tissue RNA - testis [nTPM]":"19.3","Tissue RNA - thalamus [nTPM]":"36.1","Tissue RNA - thymus [nTPM]":"12.2","Tissue RNA - thyroid gland [nTPM]":"27.8","Tissue RNA - tongue [nTPM]":"36.6","Tissue RNA - tonsil [nTPM]":"12.7","Tissue RNA - urinary bladder [nTPM]":"13.5","Tissue RNA - vagina [nTPM]":"7.5","Tissue RNA - white matter [nTPM]":"38.8","Cell RNA - A-431 [nTPM]":"25.8","Cell RNA - A549 [nTPM]":"76.5","Cell RNA - AF22 [nTPM]":"17.1","Cell RNA - AN3-CA [nTPM]":"18.0","Cell RNA - ASC diff [nTPM]":"19.1","Cell RNA - ASC TERT1 [nTPM]":"17.3","Cell RNA - BEWO [nTPM]":"20.1","Cell RNA - BJ [nTPM]":"32.3","Cell RNA - BJ hTERT+ [nTPM]":"12.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"28.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"33.5","Cell RNA - CACO-2 [nTPM]":"19.4","Cell RNA - CAPAN-2 [nTPM]":"39.9","Cell RNA - Daudi [nTPM]":"10.7","Cell RNA - EFO-21 [nTPM]":"27.0","Cell RNA - fHDF\/TERT166 [nTPM]":"22.4","Cell RNA - GAMG [nTPM]":"23.4","Cell RNA - HaCaT [nTPM]":"21.1","Cell RNA - HAP1 [nTPM]":"23.2","Cell RNA - HBEC3-KT [nTPM]":"16.3","Cell RNA - HBF TERT88 [nTPM]":"23.0","Cell RNA - HDLM-2 [nTPM]":"26.2","Cell RNA - HEK 293 [nTPM]":"23.9","Cell RNA - HEL [nTPM]":"16.5","Cell RNA - HeLa [nTPM]":"23.1","Cell RNA - Hep G2 [nTPM]":"15.2","Cell RNA - HHSteC [nTPM]":"20.6","Cell RNA - HL-60 [nTPM]":"11.0","Cell RNA - HMC-1 [nTPM]":"20.9","Cell RNA - HSkMC [nTPM]":"16.7","Cell RNA - hTCEpi [nTPM]":"17.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"23.5","Cell RNA - hTERT-HME1 [nTPM]":"12.8","Cell RNA - hTERT-RPE1 [nTPM]":"24.9","Cell RNA - HUVEC TERT2 [nTPM]":"20.5","Cell RNA - JURKAT [nTPM]":"16.7","Cell RNA - K-562 [nTPM]":"13.6","Cell RNA - Karpas-707 [nTPM]":"19.5","Cell RNA - LHCN-M2 [nTPM]":"35.7","Cell RNA - MCF7 [nTPM]":"20.0","Cell RNA - MOLT-4 [nTPM]":"21.1","Cell RNA - NB-4 [nTPM]":"9.4","Cell RNA - NTERA-2 [nTPM]":"13.1","Cell RNA - OE19 [nTPM]":"35.2","Cell RNA - PC-3 [nTPM]":"10.0","Cell RNA - REH [nTPM]":"17.4","Cell RNA - RH-30 [nTPM]":"42.5","Cell RNA - RPMI-8226 [nTPM]":"20.2","Cell RNA - RPTEC TERT1 [nTPM]":"44.1","Cell RNA - RT4 [nTPM]":"22.4","Cell RNA - SCLC-21H [nTPM]":"21.3","Cell RNA - SH-SY5Y [nTPM]":"45.5","Cell RNA - SiHa [nTPM]":"35.4","Cell RNA - SK-BR-3 [nTPM]":"38.3","Cell RNA - SK-MEL-30 [nTPM]":"17.9","Cell RNA - SuSa [nTPM]":"18.9","Cell RNA - T-47d [nTPM]":"18.8","Cell RNA - THP-1 [nTPM]":"11.5","Cell RNA - TIME [nTPM]":"30.4","Cell RNA - U-138 MG [nTPM]":"27.2","Cell RNA - U-2 OS [nTPM]":"15.2","Cell RNA - U-2197 [nTPM]":"43.7","Cell RNA - U-251 MG [nTPM]":"25.9","Cell RNA - U-266\/70 [nTPM]":"19.4","Cell RNA - U-266\/84 [nTPM]":"28.1","Cell RNA - U-698 [nTPM]":"20.7","Cell RNA - U-87 MG [nTPM]":"27.4","Cell RNA - U-937 [nTPM]":"24.6","Cell RNA - WM-115 [nTPM]":"12.0","Blood RNA - basophil [nTPM]":"12.5","Blood RNA - classical monocyte [nTPM]":"13.0","Blood RNA - eosinophil [nTPM]":"10.2","Blood RNA - gdT-cell [nTPM]":"15.3","Blood RNA - intermediate monocyte [nTPM]":"12.7","Blood RNA - MAIT T-cell [nTPM]":"15.2","Blood RNA - memory B-cell [nTPM]":"6.4","Blood RNA - memory CD4 T-cell [nTPM]":"7.5","Blood RNA - memory CD8 T-cell [nTPM]":"12.4","Blood RNA - myeloid DC [nTPM]":"13.0","Blood RNA - naive B-cell [nTPM]":"7.0","Blood RNA - naive CD4 T-cell [nTPM]":"5.0","Blood RNA - naive CD8 T-cell [nTPM]":"11.0","Blood RNA - neutrophil [nTPM]":"11.1","Blood RNA - NK-cell [nTPM]":"10.3","Blood RNA - non-classical monocyte [nTPM]":"15.1","Blood RNA - plasmacytoid DC [nTPM]":"8.5","Blood RNA - T-reg [nTPM]":"7.4","Blood RNA - total PBMC [nTPM]":"8.0","Brain RNA - amygdala [nTPM]":"31.0","Brain RNA - basal ganglia [nTPM]":"37.0","Brain RNA - cerebellum [nTPM]":"36.2","Brain RNA - cerebral cortex [nTPM]":"37.1","Brain RNA - hippocampal formation [nTPM]":"27.6","Brain RNA - hypothalamus [nTPM]":"33.1","Brain RNA - medulla oblongata [nTPM]":"37.2","Brain RNA - midbrain [nTPM]":"34.0","Brain RNA - pons [nTPM]":"38.1","Brain RNA - spinal cord [nTPM]":"36.7","Brain RNA - thalamus [nTPM]":"36.1","Brain RNA - white matter [nTPM]":"38.8","Single Cell Type RNA - Adipocytes [nTPM]":"23.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.9","Single Cell Type RNA - Astrocytes [nTPM]":"17.9","Single Cell Type RNA - B-cells [nTPM]":"16.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"30.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"83.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"25.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.6","Single Cell Type RNA - dendritic cells [nTPM]":"27.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"22.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"22.1","Single Cell Type RNA - Early spermatids [nTPM]":"43.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"33.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.2","Single Cell Type RNA - Endothelial cells [nTPM]":"18.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.2","Single Cell Type RNA - Erythroid cells [nTPM]":"8.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"20.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.6","Single Cell Type RNA - Fibroblasts [nTPM]":"16.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"41.1","Single Cell Type RNA - granulocytes [nTPM]":"12.6","Single Cell Type RNA - Granulosa cells [nTPM]":"11.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.8","Single Cell Type RNA - Hepatocytes [nTPM]":"56.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.0","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"26.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"30.4","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"25.5","Single Cell Type RNA - Langerhans cells [nTPM]":"12.5","Single Cell Type RNA - Late spermatids [nTPM]":"16.9","Single Cell Type RNA - Leydig cells [nTPM]":"16.4","Single Cell Type RNA - Macrophages [nTPM]":"22.4","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"22.4","Single Cell Type RNA - Muller glia cells [nTPM]":"47.7","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"24.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.8","Single Cell Type RNA - Paneth cells [nTPM]":"26.1","Single Cell Type RNA - Peritubular cells [nTPM]":"16.6","Single Cell Type RNA - Plasma cells [nTPM]":"14.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"64.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"48.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"32.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"47.2","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.1","Single Cell Type RNA - Spermatocytes [nTPM]":"41.0","Single Cell Type RNA - Spermatogonia [nTPM]":"8.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.4","Single Cell Type RNA - T-cells [nTPM]":"22.3","Single Cell Type RNA - Theca cells [nTPM]":"27.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.5","Single Cell Type RNA - Urothelial cells [nTPM]":"9.2"},{"Gene":"ACER3","Gene synonym":["APHC","FLJ11238","PHCA"],"Ensembl":"ENSG00000078124","Gene description":"Alkaline ceramidase 3","Uniprot":["Q9NUN7"],"Chromosome":"11","Position":"76860859-77026797","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Leukodystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"159.3","Oligodendrocytes":"335.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070087"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA070087":"AB_2732147"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.49e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.73e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.9","Tissue RNA - adrenal gland [nTPM]":"3.0","Tissue RNA - amygdala [nTPM]":"6.2","Tissue RNA - appendix [nTPM]":"4.8","Tissue RNA - basal ganglia [nTPM]":"8.5","Tissue RNA - bone marrow [nTPM]":"3.0","Tissue RNA - breast [nTPM]":"5.4","Tissue RNA - cerebellum [nTPM]":"8.5","Tissue RNA - cerebral cortex [nTPM]":"9.3","Tissue RNA - cervix [nTPM]":"5.2","Tissue RNA - choroid plexus [nTPM]":"4.0","Tissue RNA - colon [nTPM]":"6.4","Tissue RNA - duodenum [nTPM]":"6.2","Tissue RNA - endometrium 1 [nTPM]":"4.2","Tissue RNA - epididymis [nTPM]":"3.1","Tissue RNA - esophagus [nTPM]":"6.9","Tissue RNA - fallopian tube [nTPM]":"4.1","Tissue RNA - gallbladder [nTPM]":"3.2","Tissue RNA - heart muscle [nTPM]":"3.4","Tissue RNA - hippocampal formation [nTPM]":"6.3","Tissue RNA - hypothalamus [nTPM]":"8.5","Tissue RNA - kidney [nTPM]":"4.7","Tissue RNA - liver [nTPM]":"2.5","Tissue RNA - lung [nTPM]":"8.0","Tissue RNA - lymph node [nTPM]":"4.2","Tissue RNA - medulla oblongata [nTPM]":"8.6","Tissue RNA - midbrain [nTPM]":"7.1","Tissue RNA - ovary [nTPM]":"2.3","Tissue RNA - pancreas [nTPM]":"2.9","Tissue RNA - parathyroid gland [nTPM]":"3.5","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"6.2","Tissue RNA - pons [nTPM]":"9.5","Tissue RNA - prostate [nTPM]":"4.1","Tissue RNA - rectum [nTPM]":"5.5","Tissue RNA - retina [nTPM]":"2.3","Tissue RNA - salivary gland [nTPM]":"4.2","Tissue RNA - seminal vesicle [nTPM]":"2.3","Tissue RNA - skeletal muscle [nTPM]":"1.6","Tissue RNA - skin 1 [nTPM]":"2.9","Tissue RNA - small intestine [nTPM]":"4.6","Tissue RNA - smooth muscle [nTPM]":"3.9","Tissue RNA - spinal cord [nTPM]":"8.4","Tissue RNA - spleen [nTPM]":"5.6","Tissue RNA - stomach 1 [nTPM]":"3.4","Tissue RNA - testis [nTPM]":"6.0","Tissue RNA - thalamus [nTPM]":"7.3","Tissue RNA - thymus [nTPM]":"2.2","Tissue RNA - thyroid gland [nTPM]":"3.3","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"3.8","Tissue RNA - urinary bladder [nTPM]":"4.5","Tissue RNA - vagina [nTPM]":"4.4","Tissue RNA - white matter [nTPM]":"12.0","Cell RNA - A-431 [nTPM]":"7.3","Cell RNA - A549 [nTPM]":"7.7","Cell RNA - AF22 [nTPM]":"6.4","Cell RNA - AN3-CA [nTPM]":"7.6","Cell RNA - ASC diff [nTPM]":"29.2","Cell RNA - ASC TERT1 [nTPM]":"14.0","Cell RNA - BEWO [nTPM]":"5.7","Cell RNA - BJ [nTPM]":"11.2","Cell RNA - BJ hTERT+ [nTPM]":"10.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.2","Cell RNA - CACO-2 [nTPM]":"6.0","Cell RNA - CAPAN-2 [nTPM]":"7.3","Cell RNA - Daudi [nTPM]":"6.4","Cell RNA - EFO-21 [nTPM]":"8.4","Cell RNA - fHDF\/TERT166 [nTPM]":"8.0","Cell RNA - GAMG [nTPM]":"10.3","Cell RNA - HaCaT [nTPM]":"12.9","Cell RNA - HAP1 [nTPM]":"10.9","Cell RNA - HBEC3-KT [nTPM]":"10.6","Cell RNA - HBF TERT88 [nTPM]":"10.0","Cell RNA - HDLM-2 [nTPM]":"8.6","Cell RNA - HEK 293 [nTPM]":"4.3","Cell RNA - HEL [nTPM]":"9.0","Cell RNA - HeLa [nTPM]":"4.8","Cell RNA - Hep G2 [nTPM]":"3.6","Cell RNA - HHSteC [nTPM]":"8.1","Cell RNA - HL-60 [nTPM]":"9.3","Cell RNA - HMC-1 [nTPM]":"15.0","Cell RNA - HSkMC [nTPM]":"6.3","Cell RNA - hTCEpi [nTPM]":"5.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.8","Cell RNA - hTERT-HME1 [nTPM]":"10.9","Cell RNA - hTERT-RPE1 [nTPM]":"4.8","Cell RNA - HUVEC TERT2 [nTPM]":"16.8","Cell RNA - JURKAT [nTPM]":"5.8","Cell RNA - K-562 [nTPM]":"6.1","Cell RNA - Karpas-707 [nTPM]":"4.2","Cell RNA - LHCN-M2 [nTPM]":"9.9","Cell RNA - MCF7 [nTPM]":"5.9","Cell RNA - MOLT-4 [nTPM]":"0.7","Cell RNA - NB-4 [nTPM]":"6.2","Cell RNA - NTERA-2 [nTPM]":"3.6","Cell RNA - OE19 [nTPM]":"19.3","Cell RNA - PC-3 [nTPM]":"8.8","Cell RNA - REH [nTPM]":"4.3","Cell RNA - RH-30 [nTPM]":"22.8","Cell RNA - RPMI-8226 [nTPM]":"5.0","Cell RNA - RPTEC TERT1 [nTPM]":"6.8","Cell RNA - RT4 [nTPM]":"7.2","Cell RNA - SCLC-21H [nTPM]":"2.2","Cell RNA - SH-SY5Y [nTPM]":"5.5","Cell RNA - SiHa [nTPM]":"13.9","Cell RNA - SK-BR-3 [nTPM]":"12.6","Cell RNA - SK-MEL-30 [nTPM]":"3.5","Cell RNA - SuSa [nTPM]":"4.9","Cell RNA - T-47d [nTPM]":"10.7","Cell RNA - THP-1 [nTPM]":"5.1","Cell RNA - TIME [nTPM]":"22.2","Cell RNA - U-138 MG [nTPM]":"8.2","Cell RNA - U-2 OS [nTPM]":"6.4","Cell RNA - U-2197 [nTPM]":"23.3","Cell RNA - U-251 MG [nTPM]":"8.3","Cell RNA - U-266\/70 [nTPM]":"3.1","Cell RNA - U-266\/84 [nTPM]":"7.1","Cell RNA - U-698 [nTPM]":"8.6","Cell RNA - U-87 MG [nTPM]":"5.1","Cell RNA - U-937 [nTPM]":"4.7","Cell RNA - WM-115 [nTPM]":"8.9","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"4.3","Blood RNA - eosinophil [nTPM]":"2.5","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"3.1","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"1.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"4.6","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"2.4","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"1.6","Brain RNA - amygdala [nTPM]":"6.2","Brain RNA - basal ganglia [nTPM]":"8.5","Brain RNA - cerebellum [nTPM]":"8.5","Brain RNA - cerebral cortex [nTPM]":"9.3","Brain RNA - hippocampal formation [nTPM]":"6.3","Brain RNA - hypothalamus [nTPM]":"8.5","Brain RNA - medulla oblongata [nTPM]":"8.6","Brain RNA - midbrain [nTPM]":"7.1","Brain RNA - pons [nTPM]":"9.5","Brain RNA - spinal cord [nTPM]":"8.4","Brain RNA - thalamus [nTPM]":"7.3","Brain RNA - white matter [nTPM]":"12.0","Single Cell Type RNA - Adipocytes [nTPM]":"32.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"35.0","Single Cell Type RNA - Astrocytes [nTPM]":"52.9","Single Cell Type RNA - B-cells [nTPM]":"11.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"31.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"33.0","Single Cell Type RNA - Bipolar cells [nTPM]":"18.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"27.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.6","Single Cell Type RNA - dendritic cells [nTPM]":"11.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"54.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"15.5","Single Cell Type RNA - Early spermatids [nTPM]":"66.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.0","Single Cell Type RNA - Endothelial cells [nTPM]":"29.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"13.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"65.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.5","Single Cell Type RNA - Fibroblasts [nTPM]":"17.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"26.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.5","Single Cell Type RNA - granulocytes [nTPM]":"83.5","Single Cell Type RNA - Granulosa cells [nTPM]":"30.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"27.8","Single Cell Type RNA - Hepatocytes [nTPM]":"10.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"44.4","Single Cell Type RNA - Horizontal cells [nTPM]":"43.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"71.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"30.5","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"64.1","Single Cell Type RNA - Langerhans cells [nTPM]":"67.1","Single Cell Type RNA - Late spermatids [nTPM]":"31.7","Single Cell Type RNA - Leydig cells [nTPM]":"20.2","Single Cell Type RNA - Macrophages [nTPM]":"64.0","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"61.8","Single Cell Type RNA - monocytes [nTPM]":"40.0","Single Cell Type RNA - Muller glia cells [nTPM]":"11.3","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"159.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"335.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.6","Single Cell Type RNA - Paneth cells [nTPM]":"37.9","Single Cell Type RNA - Peritubular cells [nTPM]":"25.9","Single Cell Type RNA - Plasma cells [nTPM]":"8.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.0","Single Cell Type RNA - Spermatocytes [nTPM]":"69.8","Single Cell Type RNA - Spermatogonia [nTPM]":"25.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"26.8","Single Cell Type RNA - T-cells [nTPM]":"15.2","Single Cell Type RNA - Theca cells [nTPM]":"7.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.1","Single Cell Type RNA - Urothelial cells [nTPM]":"24.1"},{"Gene":"ACO2","Gene synonym":["ACONM"],"Ensembl":"ENSG00000100412","Gene description":"Aconitase 2","Uniprot":["Q99798"],"Chromosome":"22","Position":"41447830-41529273","Protein class":["Citric acid cycle related proteins","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Tricarboxylic acid cycle"],"Molecular function":["Lyase"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"567.7","skeletal muscle":"660.4","tongue":"695.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"374.2","Proximal tubular cells":"285.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001097"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2000000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA001097":"AB_1078092"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Tissue RNA - adipose tissue [nTPM]":"88.8","Tissue RNA - adrenal gland [nTPM]":"81.6","Tissue RNA - amygdala [nTPM]":"154.2","Tissue RNA - appendix [nTPM]":"38.6","Tissue RNA - basal ganglia [nTPM]":"152.2","Tissue RNA - bone marrow [nTPM]":"32.0","Tissue RNA - breast [nTPM]":"52.4","Tissue RNA - cerebellum [nTPM]":"153.0","Tissue RNA - cerebral cortex [nTPM]":"190.0","Tissue RNA - cervix [nTPM]":"39.5","Tissue RNA - choroid plexus [nTPM]":"160.1","Tissue RNA - colon [nTPM]":"94.4","Tissue RNA - duodenum [nTPM]":"162.9","Tissue RNA - endometrium 1 [nTPM]":"42.0","Tissue RNA - epididymis [nTPM]":"26.1","Tissue RNA - esophagus [nTPM]":"60.4","Tissue RNA - fallopian tube [nTPM]":"53.6","Tissue RNA - gallbladder [nTPM]":"36.5","Tissue RNA - heart muscle [nTPM]":"567.7","Tissue RNA - hippocampal formation [nTPM]":"155.2","Tissue RNA - hypothalamus [nTPM]":"153.1","Tissue RNA - kidney [nTPM]":"138.9","Tissue RNA - liver [nTPM]":"73.9","Tissue RNA - lung [nTPM]":"40.7","Tissue RNA - lymph node [nTPM]":"40.5","Tissue RNA - medulla oblongata [nTPM]":"146.1","Tissue RNA - midbrain [nTPM]":"145.3","Tissue RNA - ovary [nTPM]":"30.8","Tissue RNA - pancreas [nTPM]":"53.8","Tissue RNA - parathyroid gland [nTPM]":"233.8","Tissue RNA - pituitary gland [nTPM]":"33.6","Tissue RNA - placenta [nTPM]":"30.5","Tissue RNA - pons [nTPM]":"147.8","Tissue RNA - prostate [nTPM]":"41.2","Tissue RNA - rectum [nTPM]":"69.6","Tissue RNA - retina [nTPM]":"46.9","Tissue RNA - salivary gland [nTPM]":"72.0","Tissue RNA - seminal vesicle [nTPM]":"49.5","Tissue RNA - skeletal muscle [nTPM]":"660.4","Tissue RNA - skin 1 [nTPM]":"45.5","Tissue RNA - small intestine [nTPM]":"158.5","Tissue RNA - smooth muscle [nTPM]":"43.7","Tissue RNA - spinal cord [nTPM]":"152.5","Tissue RNA - spleen [nTPM]":"44.7","Tissue RNA - stomach 1 [nTPM]":"110.2","Tissue RNA - testis [nTPM]":"35.1","Tissue RNA - thalamus [nTPM]":"186.3","Tissue RNA - thymus [nTPM]":"38.0","Tissue RNA - thyroid gland [nTPM]":"53.7","Tissue RNA - tongue [nTPM]":"695.8","Tissue RNA - tonsil [nTPM]":"43.3","Tissue RNA - urinary bladder [nTPM]":"52.5","Tissue RNA - vagina [nTPM]":"42.4","Tissue RNA - white matter [nTPM]":"159.6","Cell RNA - A-431 [nTPM]":"47.2","Cell RNA - A549 [nTPM]":"55.8","Cell RNA - AF22 [nTPM]":"56.5","Cell RNA - AN3-CA [nTPM]":"116.3","Cell RNA - ASC diff [nTPM]":"101.2","Cell RNA - ASC TERT1 [nTPM]":"69.8","Cell RNA - BEWO [nTPM]":"78.7","Cell RNA - BJ [nTPM]":"43.7","Cell RNA - BJ hTERT+ [nTPM]":"60.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"79.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"71.9","Cell RNA - CACO-2 [nTPM]":"81.2","Cell RNA - CAPAN-2 [nTPM]":"63.5","Cell RNA - Daudi [nTPM]":"115.7","Cell RNA - EFO-21 [nTPM]":"72.2","Cell RNA - fHDF\/TERT166 [nTPM]":"70.6","Cell RNA - GAMG [nTPM]":"60.3","Cell RNA - HaCaT [nTPM]":"109.8","Cell RNA - HAP1 [nTPM]":"108.8","Cell RNA - HBEC3-KT [nTPM]":"88.3","Cell RNA - HBF TERT88 [nTPM]":"42.8","Cell RNA - HDLM-2 [nTPM]":"75.8","Cell RNA - HEK 293 [nTPM]":"80.2","Cell RNA - HEL [nTPM]":"51.0","Cell RNA - HeLa [nTPM]":"73.7","Cell RNA - Hep G2 [nTPM]":"95.0","Cell RNA - HHSteC [nTPM]":"86.7","Cell RNA - HL-60 [nTPM]":"147.8","Cell RNA - HMC-1 [nTPM]":"77.8","Cell RNA - HSkMC [nTPM]":"120.8","Cell RNA - hTCEpi [nTPM]":"64.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"78.9","Cell RNA - hTERT-HME1 [nTPM]":"83.2","Cell RNA - hTERT-RPE1 [nTPM]":"61.7","Cell RNA - HUVEC TERT2 [nTPM]":"81.2","Cell RNA - JURKAT [nTPM]":"61.5","Cell RNA - K-562 [nTPM]":"72.9","Cell RNA - Karpas-707 [nTPM]":"118.4","Cell RNA - LHCN-M2 [nTPM]":"65.4","Cell RNA - MCF7 [nTPM]":"91.7","Cell RNA - MOLT-4 [nTPM]":"73.7","Cell RNA - NB-4 [nTPM]":"47.9","Cell RNA - NTERA-2 [nTPM]":"37.0","Cell RNA - OE19 [nTPM]":"282.6","Cell RNA - PC-3 [nTPM]":"115.1","Cell RNA - REH [nTPM]":"102.3","Cell RNA - RH-30 [nTPM]":"37.8","Cell RNA - RPMI-8226 [nTPM]":"162.1","Cell RNA - RPTEC TERT1 [nTPM]":"106.8","Cell RNA - RT4 [nTPM]":"97.3","Cell RNA - SCLC-21H [nTPM]":"37.8","Cell RNA - SH-SY5Y [nTPM]":"33.9","Cell RNA - SiHa [nTPM]":"112.2","Cell RNA - SK-BR-3 [nTPM]":"128.7","Cell RNA - SK-MEL-30 [nTPM]":"82.0","Cell RNA - SuSa [nTPM]":"44.9","Cell RNA - T-47d [nTPM]":"74.9","Cell RNA - THP-1 [nTPM]":"74.7","Cell RNA - TIME [nTPM]":"55.5","Cell RNA - U-138 MG [nTPM]":"60.0","Cell RNA - U-2 OS [nTPM]":"68.7","Cell RNA - U-2197 [nTPM]":"50.2","Cell RNA - U-251 MG [nTPM]":"45.0","Cell RNA - U-266\/70 [nTPM]":"64.7","Cell RNA - U-266\/84 [nTPM]":"92.1","Cell RNA - U-698 [nTPM]":"80.6","Cell RNA - U-87 MG [nTPM]":"102.0","Cell RNA - U-937 [nTPM]":"64.0","Cell RNA - WM-115 [nTPM]":"66.5","Blood RNA - basophil [nTPM]":"10.3","Blood RNA - classical monocyte [nTPM]":"52.9","Blood RNA - eosinophil [nTPM]":"18.1","Blood RNA - gdT-cell [nTPM]":"32.0","Blood RNA - intermediate monocyte [nTPM]":"76.4","Blood RNA - MAIT T-cell [nTPM]":"29.3","Blood RNA - memory B-cell [nTPM]":"49.4","Blood RNA - memory CD4 T-cell [nTPM]":"25.5","Blood RNA - memory CD8 T-cell [nTPM]":"34.9","Blood RNA - myeloid DC [nTPM]":"69.0","Blood RNA - naive B-cell [nTPM]":"46.4","Blood RNA - naive CD4 T-cell [nTPM]":"29.2","Blood RNA - naive CD8 T-cell [nTPM]":"30.8","Blood RNA - neutrophil [nTPM]":"9.0","Blood RNA - NK-cell [nTPM]":"39.4","Blood RNA - non-classical monocyte [nTPM]":"97.1","Blood RNA - plasmacytoid DC [nTPM]":"24.0","Blood RNA - T-reg [nTPM]":"41.2","Blood RNA - total PBMC [nTPM]":"58.6","Brain RNA - amygdala [nTPM]":"154.2","Brain RNA - basal ganglia [nTPM]":"152.2","Brain RNA - cerebellum [nTPM]":"153.0","Brain RNA - cerebral cortex [nTPM]":"190.0","Brain RNA - hippocampal formation [nTPM]":"155.2","Brain RNA - hypothalamus [nTPM]":"153.1","Brain RNA - medulla oblongata [nTPM]":"146.1","Brain RNA - midbrain [nTPM]":"145.3","Brain RNA - pons [nTPM]":"147.8","Brain RNA - spinal cord [nTPM]":"152.5","Brain RNA - thalamus [nTPM]":"186.3","Brain RNA - white matter [nTPM]":"159.6","Single Cell Type RNA - Adipocytes [nTPM]":"26.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.8","Single Cell Type RNA - Astrocytes [nTPM]":"45.4","Single Cell Type RNA - B-cells [nTPM]":"49.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"54.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"102.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.3","Single Cell Type RNA - Bipolar cells [nTPM]":"60.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"28.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"64.3","Single Cell Type RNA - Club cells [nTPM]":"63.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"60.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"81.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"100.3","Single Cell Type RNA - dendritic cells [nTPM]":"33.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"190.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"131.0","Single Cell Type RNA - Ductal cells [nTPM]":"58.3","Single Cell Type RNA - Early spermatids [nTPM]":"14.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"37.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.7","Single Cell Type RNA - Endothelial cells [nTPM]":"26.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"53.2","Single Cell Type RNA - Erythroid cells [nTPM]":"30.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"28.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"42.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"60.0","Single Cell Type RNA - Fibroblasts [nTPM]":"24.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"77.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"37.1","Single Cell Type RNA - granulocytes [nTPM]":"40.6","Single Cell Type RNA - Granulosa cells [nTPM]":"56.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.7","Single Cell Type RNA - Hepatocytes [nTPM]":"64.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"91.5","Single Cell Type RNA - Horizontal cells [nTPM]":"53.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"34.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"99.1","Single Cell Type RNA - Ionocytes [nTPM]":"89.5","Single Cell Type RNA - Kupffer cells [nTPM]":"35.5","Single Cell Type RNA - Langerhans cells [nTPM]":"26.4","Single Cell Type RNA - Late spermatids [nTPM]":"8.9","Single Cell Type RNA - Leydig cells [nTPM]":"24.2","Single Cell Type RNA - Macrophages [nTPM]":"39.2","Single Cell Type RNA - Melanocytes [nTPM]":"35.6","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"68.3","Single Cell Type RNA - Muller glia cells [nTPM]":"73.9","Single Cell Type RNA - NK-cells [nTPM]":"34.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"43.9","Single Cell Type RNA - Paneth cells [nTPM]":"103.5","Single Cell Type RNA - Peritubular cells [nTPM]":"27.8","Single Cell Type RNA - Plasma cells [nTPM]":"63.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"34.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"374.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"285.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"59.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"73.5","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"28.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"38.4","Single Cell Type RNA - Spermatocytes [nTPM]":"26.4","Single Cell Type RNA - Spermatogonia [nTPM]":"38.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"35.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"193.2","Single Cell Type RNA - T-cells [nTPM]":"30.7","Single Cell Type RNA - Theca cells [nTPM]":"54.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"113.6","Single Cell Type RNA - Urothelial cells [nTPM]":"64.9"},{"Gene":"ACOX1","Gene synonym":["PALMCOX"],"Ensembl":"ENSG00000161533","Gene description":"Acyl-CoA oxidase 1","Uniprot":["Q15067"],"Chromosome":"17","Position":"75941507-75979177","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Deafness","Disease variant","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"191.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"199.8","Hepatocytes":"287.4","Proximal enterocytes":"238.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"77.2","neutrophil":"113.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"113.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"96.9","RT4":"129.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB021094","HPA021192","HPA021195","HPA028759"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Peroxisomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"96000","Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Peroxisomes"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"CAB021094":"AB_10261667","HPA021192":"AB_1844527","HPA021195":"AB_1844528","HPA028759":"AB_10601352"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.25e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Tissue RNA - adipose tissue [nTPM]":"37.8","Tissue RNA - adrenal gland [nTPM]":"18.1","Tissue RNA - amygdala [nTPM]":"16.1","Tissue RNA - appendix [nTPM]":"10.6","Tissue RNA - basal ganglia [nTPM]":"18.2","Tissue RNA - bone marrow [nTPM]":"8.8","Tissue RNA - breast [nTPM]":"17.1","Tissue RNA - cerebellum [nTPM]":"17.4","Tissue RNA - cerebral cortex [nTPM]":"15.1","Tissue RNA - cervix [nTPM]":"11.0","Tissue RNA - choroid plexus [nTPM]":"21.3","Tissue RNA - colon [nTPM]":"40.9","Tissue RNA - duodenum [nTPM]":"62.5","Tissue RNA - endometrium 1 [nTPM]":"9.3","Tissue RNA - epididymis [nTPM]":"9.8","Tissue RNA - esophagus [nTPM]":"30.4","Tissue RNA - fallopian tube [nTPM]":"9.9","Tissue RNA - gallbladder [nTPM]":"14.9","Tissue RNA - heart muscle [nTPM]":"23.0","Tissue RNA - hippocampal formation [nTPM]":"14.3","Tissue RNA - hypothalamus [nTPM]":"17.5","Tissue RNA - kidney [nTPM]":"40.3","Tissue RNA - liver [nTPM]":"191.5","Tissue RNA - lung [nTPM]":"13.6","Tissue RNA - lymph node [nTPM]":"6.2","Tissue RNA - medulla oblongata [nTPM]":"16.6","Tissue RNA - midbrain [nTPM]":"17.9","Tissue RNA - ovary [nTPM]":"9.5","Tissue RNA - pancreas [nTPM]":"39.7","Tissue RNA - parathyroid gland [nTPM]":"18.8","Tissue RNA - pituitary gland [nTPM]":"12.6","Tissue RNA - placenta [nTPM]":"17.3","Tissue RNA - pons [nTPM]":"15.9","Tissue RNA - prostate [nTPM]":"18.4","Tissue RNA - rectum [nTPM]":"27.1","Tissue RNA - retina [nTPM]":"16.1","Tissue RNA - salivary gland [nTPM]":"15.4","Tissue RNA - seminal vesicle [nTPM]":"11.8","Tissue RNA - skeletal muscle [nTPM]":"30.1","Tissue RNA - skin 1 [nTPM]":"24.8","Tissue RNA - small intestine [nTPM]":"51.4","Tissue RNA - smooth muscle [nTPM]":"11.1","Tissue RNA - spinal cord [nTPM]":"17.5","Tissue RNA - spleen [nTPM]":"10.5","Tissue RNA - stomach 1 [nTPM]":"27.4","Tissue RNA - testis [nTPM]":"9.3","Tissue RNA - thalamus [nTPM]":"20.6","Tissue RNA - thymus [nTPM]":"8.3","Tissue RNA - thyroid gland [nTPM]":"17.0","Tissue RNA - tongue [nTPM]":"29.2","Tissue RNA - tonsil [nTPM]":"12.1","Tissue RNA - urinary bladder [nTPM]":"19.5","Tissue RNA - vagina [nTPM]":"12.7","Tissue RNA - white matter [nTPM]":"18.9","Cell RNA - A-431 [nTPM]":"16.3","Cell RNA - A549 [nTPM]":"24.5","Cell RNA - AF22 [nTPM]":"7.2","Cell RNA - AN3-CA [nTPM]":"9.9","Cell RNA - ASC diff [nTPM]":"34.0","Cell RNA - ASC TERT1 [nTPM]":"14.4","Cell RNA - BEWO [nTPM]":"96.9","Cell RNA - BJ [nTPM]":"11.8","Cell RNA - BJ hTERT+ [nTPM]":"11.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.8","Cell RNA - CACO-2 [nTPM]":"16.4","Cell RNA - CAPAN-2 [nTPM]":"24.0","Cell RNA - Daudi [nTPM]":"9.1","Cell RNA - EFO-21 [nTPM]":"14.0","Cell RNA - fHDF\/TERT166 [nTPM]":"17.9","Cell RNA - GAMG [nTPM]":"12.5","Cell RNA - HaCaT [nTPM]":"9.9","Cell RNA - HAP1 [nTPM]":"28.7","Cell RNA - HBEC3-KT [nTPM]":"12.4","Cell RNA - HBF TERT88 [nTPM]":"19.2","Cell RNA - HDLM-2 [nTPM]":"10.0","Cell RNA - HEK 293 [nTPM]":"9.5","Cell RNA - HEL [nTPM]":"10.9","Cell RNA - HeLa [nTPM]":"13.1","Cell RNA - Hep G2 [nTPM]":"47.2","Cell RNA - HHSteC [nTPM]":"19.4","Cell RNA - HL-60 [nTPM]":"9.7","Cell RNA - HMC-1 [nTPM]":"7.8","Cell RNA - HSkMC [nTPM]":"24.0","Cell RNA - hTCEpi [nTPM]":"9.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.7","Cell RNA - hTERT-HME1 [nTPM]":"9.2","Cell RNA - hTERT-RPE1 [nTPM]":"13.1","Cell RNA - HUVEC TERT2 [nTPM]":"32.3","Cell RNA - JURKAT [nTPM]":"13.6","Cell RNA - K-562 [nTPM]":"12.3","Cell RNA - Karpas-707 [nTPM]":"8.9","Cell RNA - LHCN-M2 [nTPM]":"14.0","Cell RNA - MCF7 [nTPM]":"45.3","Cell RNA - MOLT-4 [nTPM]":"26.3","Cell RNA - NB-4 [nTPM]":"7.0","Cell RNA - NTERA-2 [nTPM]":"4.9","Cell RNA - OE19 [nTPM]":"36.8","Cell RNA - PC-3 [nTPM]":"19.8","Cell RNA - REH [nTPM]":"13.4","Cell RNA - RH-30 [nTPM]":"21.3","Cell RNA - RPMI-8226 [nTPM]":"10.2","Cell RNA - RPTEC TERT1 [nTPM]":"20.7","Cell RNA - RT4 [nTPM]":"129.1","Cell RNA - SCLC-21H [nTPM]":"8.7","Cell RNA - SH-SY5Y [nTPM]":"12.6","Cell RNA - SiHa [nTPM]":"30.6","Cell RNA - SK-BR-3 [nTPM]":"46.5","Cell RNA - SK-MEL-30 [nTPM]":"11.4","Cell RNA - SuSa [nTPM]":"21.2","Cell RNA - T-47d [nTPM]":"32.6","Cell RNA - THP-1 [nTPM]":"11.3","Cell RNA - TIME [nTPM]":"20.9","Cell RNA - U-138 MG [nTPM]":"18.2","Cell RNA - U-2 OS [nTPM]":"13.4","Cell RNA - U-2197 [nTPM]":"15.2","Cell RNA - U-251 MG [nTPM]":"11.5","Cell RNA - U-266\/70 [nTPM]":"14.4","Cell RNA - U-266\/84 [nTPM]":"11.0","Cell RNA - U-698 [nTPM]":"4.0","Cell RNA - U-87 MG [nTPM]":"10.0","Cell RNA - U-937 [nTPM]":"9.7","Cell RNA - WM-115 [nTPM]":"11.4","Blood RNA - basophil [nTPM]":"77.2","Blood RNA - classical monocyte [nTPM]":"18.3","Blood RNA - eosinophil [nTPM]":"5.2","Blood RNA - gdT-cell [nTPM]":"6.9","Blood RNA - intermediate monocyte [nTPM]":"14.2","Blood RNA - MAIT T-cell [nTPM]":"8.2","Blood RNA - memory B-cell [nTPM]":"5.4","Blood RNA - memory CD4 T-cell [nTPM]":"6.6","Blood RNA - memory CD8 T-cell [nTPM]":"8.8","Blood RNA - myeloid DC [nTPM]":"10.3","Blood RNA - naive B-cell [nTPM]":"4.5","Blood RNA - naive CD4 T-cell [nTPM]":"7.2","Blood RNA - naive CD8 T-cell [nTPM]":"7.1","Blood RNA - neutrophil [nTPM]":"113.7","Blood RNA - NK-cell [nTPM]":"7.2","Blood RNA - non-classical monocyte [nTPM]":"9.4","Blood RNA - plasmacytoid DC [nTPM]":"9.4","Blood RNA - T-reg [nTPM]":"9.3","Blood RNA - total PBMC [nTPM]":"8.0","Brain RNA - amygdala [nTPM]":"16.1","Brain RNA - basal ganglia [nTPM]":"18.2","Brain RNA - cerebellum [nTPM]":"17.4","Brain RNA - cerebral cortex [nTPM]":"15.1","Brain RNA - hippocampal formation [nTPM]":"14.3","Brain RNA - hypothalamus [nTPM]":"17.5","Brain RNA - medulla oblongata [nTPM]":"16.6","Brain RNA - midbrain [nTPM]":"17.9","Brain RNA - pons [nTPM]":"15.9","Brain RNA - spinal cord [nTPM]":"17.5","Brain RNA - thalamus [nTPM]":"20.6","Brain RNA - white matter [nTPM]":"18.9","Single Cell Type RNA - Adipocytes [nTPM]":"28.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.0","Single Cell Type RNA - Astrocytes [nTPM]":"25.1","Single Cell Type RNA - B-cells [nTPM]":"10.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"26.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.1","Single Cell Type RNA - Bipolar cells [nTPM]":"27.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"47.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"51.5","Single Cell Type RNA - Club cells [nTPM]":"23.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"37.7","Single Cell Type RNA - dendritic cells [nTPM]":"12.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"199.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"22.9","Single Cell Type RNA - Early spermatids [nTPM]":"11.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.7","Single Cell Type RNA - Endothelial cells [nTPM]":"18.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"34.4","Single Cell Type RNA - Erythroid cells [nTPM]":"21.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"40.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"46.5","Single Cell Type RNA - Fibroblasts [nTPM]":"19.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"88.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.1","Single Cell Type RNA - granulocytes [nTPM]":"17.1","Single Cell Type RNA - Granulosa cells [nTPM]":"21.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.8","Single Cell Type RNA - Hepatocytes [nTPM]":"287.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.4","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"44.5","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"35.4","Single Cell Type RNA - Langerhans cells [nTPM]":"14.1","Single Cell Type RNA - Late spermatids [nTPM]":"7.1","Single Cell Type RNA - Leydig cells [nTPM]":"29.8","Single Cell Type RNA - Macrophages [nTPM]":"23.7","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"36.3","Single Cell Type RNA - Muller glia cells [nTPM]":"61.9","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"22.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"34.2","Single Cell Type RNA - Paneth cells [nTPM]":"100.0","Single Cell Type RNA - Peritubular cells [nTPM]":"47.0","Single Cell Type RNA - Plasma cells [nTPM]":"18.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"24.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"238.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"107.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"28.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.2","Single Cell Type RNA - Spermatocytes [nTPM]":"5.5","Single Cell Type RNA - Spermatogonia [nTPM]":"11.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"30.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"43.2","Single Cell Type RNA - T-cells [nTPM]":"13.2","Single Cell Type RNA - Theca cells [nTPM]":"17.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"41.9","Single Cell Type RNA - Urothelial cells [nTPM]":"31.7"},{"Gene":"ACOX2","Gene synonym":["BRCACOX","BRCOX","THCCox"],"Ensembl":"ENSG00000168306","Gene description":"Acyl-CoA oxidase 2","Uniprot":["Q99424"],"Chromosome":"3","Position":"58505136-58537283","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"liver":"177.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"89.0","Proximal enterocytes":"27.9","Proximal tubular cells":"51.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"25.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"16.4","ASC TERT1":"25.9","fHDF\/TERT166":"9.2","Hep G2":"10.8","HSkMC":"17.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038280","HPA064845"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"29000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA038280":"AB_10672623","HPA064845":"AB_2685368"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.67e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-3"},"Tissue RNA - adipose tissue [nTPM]":"8.8","Tissue RNA - adrenal gland [nTPM]":"8.3","Tissue RNA - amygdala [nTPM]":"4.1","Tissue RNA - appendix [nTPM]":"2.1","Tissue RNA - basal ganglia [nTPM]":"4.6","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"5.8","Tissue RNA - cerebellum [nTPM]":"4.4","Tissue RNA - cerebral cortex [nTPM]":"4.5","Tissue RNA - cervix [nTPM]":"9.3","Tissue RNA - choroid plexus [nTPM]":"16.8","Tissue RNA - colon [nTPM]":"12.9","Tissue RNA - duodenum [nTPM]":"25.4","Tissue RNA - endometrium 1 [nTPM]":"9.4","Tissue RNA - epididymis [nTPM]":"5.8","Tissue RNA - esophagus [nTPM]":"6.3","Tissue RNA - fallopian tube [nTPM]":"10.8","Tissue RNA - gallbladder [nTPM]":"8.2","Tissue RNA - heart muscle [nTPM]":"16.7","Tissue RNA - hippocampal formation [nTPM]":"4.3","Tissue RNA - hypothalamus [nTPM]":"4.5","Tissue RNA - kidney [nTPM]":"42.1","Tissue RNA - liver [nTPM]":"177.3","Tissue RNA - lung [nTPM]":"6.2","Tissue RNA - lymph node [nTPM]":"1.7","Tissue RNA - medulla oblongata [nTPM]":"5.3","Tissue RNA - midbrain [nTPM]":"4.8","Tissue RNA - ovary [nTPM]":"11.2","Tissue RNA - pancreas [nTPM]":"4.6","Tissue RNA - parathyroid gland [nTPM]":"9.6","Tissue RNA - pituitary gland [nTPM]":"4.6","Tissue RNA - placenta [nTPM]":"3.4","Tissue RNA - pons [nTPM]":"4.4","Tissue RNA - prostate [nTPM]":"10.8","Tissue RNA - rectum [nTPM]":"8.3","Tissue RNA - retina [nTPM]":"1.8","Tissue RNA - salivary gland [nTPM]":"7.2","Tissue RNA - seminal vesicle [nTPM]":"9.8","Tissue RNA - skeletal muscle [nTPM]":"8.2","Tissue RNA - skin 1 [nTPM]":"2.9","Tissue RNA - small intestine [nTPM]":"21.6","Tissue RNA - smooth muscle [nTPM]":"11.2","Tissue RNA - spinal cord [nTPM]":"4.5","Tissue RNA - spleen [nTPM]":"1.4","Tissue RNA - stomach 1 [nTPM]":"4.0","Tissue RNA - testis [nTPM]":"4.9","Tissue RNA - thalamus [nTPM]":"4.9","Tissue RNA - thymus [nTPM]":"4.0","Tissue RNA - thyroid gland [nTPM]":"16.1","Tissue RNA - tongue [nTPM]":"17.0","Tissue RNA - tonsil [nTPM]":"1.2","Tissue RNA - urinary bladder [nTPM]":"8.7","Tissue RNA - vagina [nTPM]":"6.0","Tissue RNA - white matter [nTPM]":"4.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"16.4","Cell RNA - ASC TERT1 [nTPM]":"25.9","Cell RNA - BEWO [nTPM]":"4.7","Cell RNA - BJ [nTPM]":"3.1","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"0.8","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"9.2","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"10.8","Cell RNA - HHSteC [nTPM]":"2.3","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"17.4","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"2.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.6","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.6","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.1","Brain RNA - basal ganglia [nTPM]":"4.6","Brain RNA - cerebellum [nTPM]":"4.4","Brain RNA - cerebral cortex [nTPM]":"4.5","Brain RNA - hippocampal formation [nTPM]":"4.3","Brain RNA - hypothalamus [nTPM]":"4.5","Brain RNA - medulla oblongata [nTPM]":"5.3","Brain RNA - midbrain [nTPM]":"4.8","Brain RNA - pons [nTPM]":"4.4","Brain RNA - spinal cord [nTPM]":"4.5","Brain RNA - thalamus [nTPM]":"4.9","Brain RNA - white matter [nTPM]":"4.1","Single Cell Type RNA - Adipocytes [nTPM]":"1.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.8","Single Cell Type RNA - Astrocytes [nTPM]":"11.1","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"0.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.3","Single Cell Type RNA - Endothelial cells [nTPM]":"1.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"8.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"8.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"89.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.2","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"1.8","Single Cell Type RNA - Leydig cells [nTPM]":"10.8","Single Cell Type RNA - Macrophages [nTPM]":"1.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.5","Single Cell Type RNA - Muller glia cells [nTPM]":"10.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.8","Single Cell Type RNA - Peritubular cells [nTPM]":"8.6","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"27.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"51.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"9.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.6","Single Cell Type RNA - Urothelial cells [nTPM]":"3.8"},{"Gene":"ACP2","Gene synonym":["LAP"],"Ensembl":"ENSG00000134575","Gene description":"Acid phosphatase 2, lysosomal","Uniprot":["P11117"],"Chromosome":"11","Position":"47239302-47248906","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"89.3","Hofbauer cells":"113.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"69.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"monocytes":"69.9"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.04e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Tissue RNA - adipose tissue [nTPM]":"25.2","Tissue RNA - adrenal gland [nTPM]":"36.6","Tissue RNA - amygdala [nTPM]":"17.3","Tissue RNA - appendix [nTPM]":"22.9","Tissue RNA - basal ganglia [nTPM]":"17.1","Tissue RNA - bone marrow [nTPM]":"6.4","Tissue RNA - breast [nTPM]":"21.8","Tissue RNA - cerebellum [nTPM]":"17.0","Tissue RNA - cerebral cortex [nTPM]":"18.5","Tissue RNA - cervix [nTPM]":"16.5","Tissue RNA - choroid plexus [nTPM]":"22.1","Tissue RNA - colon [nTPM]":"23.3","Tissue RNA - duodenum [nTPM]":"42.9","Tissue RNA - endometrium 1 [nTPM]":"15.8","Tissue RNA - epididymis [nTPM]":"29.8","Tissue RNA - esophagus [nTPM]":"14.3","Tissue RNA - fallopian tube [nTPM]":"14.1","Tissue RNA - gallbladder [nTPM]":"19.6","Tissue RNA - heart muscle [nTPM]":"21.7","Tissue RNA - hippocampal formation [nTPM]":"19.8","Tissue RNA - hypothalamus [nTPM]":"26.0","Tissue RNA - kidney [nTPM]":"27.4","Tissue RNA - liver [nTPM]":"80.5","Tissue RNA - lung [nTPM]":"21.4","Tissue RNA - lymph node [nTPM]":"29.4","Tissue RNA - medulla oblongata [nTPM]":"20.8","Tissue RNA - midbrain [nTPM]":"19.6","Tissue RNA - ovary [nTPM]":"11.1","Tissue RNA - pancreas [nTPM]":"45.9","Tissue RNA - parathyroid gland [nTPM]":"21.3","Tissue RNA - pituitary gland [nTPM]":"21.3","Tissue RNA - placenta [nTPM]":"28.7","Tissue RNA - pons [nTPM]":"23.1","Tissue RNA - prostate [nTPM]":"25.4","Tissue RNA - rectum [nTPM]":"18.1","Tissue RNA - retina [nTPM]":"11.9","Tissue RNA - salivary gland [nTPM]":"50.3","Tissue RNA - seminal vesicle [nTPM]":"18.3","Tissue RNA - skeletal muscle [nTPM]":"14.0","Tissue RNA - skin 1 [nTPM]":"11.4","Tissue RNA - small intestine [nTPM]":"31.9","Tissue RNA - smooth muscle [nTPM]":"16.9","Tissue RNA - spinal cord [nTPM]":"16.9","Tissue RNA - spleen [nTPM]":"29.1","Tissue RNA - stomach 1 [nTPM]":"24.8","Tissue RNA - testis [nTPM]":"12.2","Tissue RNA - thalamus [nTPM]":"22.0","Tissue RNA - thymus [nTPM]":"13.7","Tissue RNA - thyroid gland [nTPM]":"19.3","Tissue RNA - tongue [nTPM]":"14.8","Tissue RNA - tonsil [nTPM]":"15.3","Tissue RNA - urinary bladder [nTPM]":"22.0","Tissue RNA - vagina [nTPM]":"13.1","Tissue RNA - white matter [nTPM]":"17.2","Cell RNA - A-431 [nTPM]":"16.5","Cell RNA - A549 [nTPM]":"33.5","Cell RNA - AF22 [nTPM]":"31.9","Cell RNA - AN3-CA [nTPM]":"28.2","Cell RNA - ASC diff [nTPM]":"28.1","Cell RNA - ASC TERT1 [nTPM]":"13.6","Cell RNA - BEWO [nTPM]":"24.4","Cell RNA - BJ [nTPM]":"26.6","Cell RNA - BJ hTERT+ [nTPM]":"47.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"47.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"49.4","Cell RNA - CACO-2 [nTPM]":"23.3","Cell RNA - CAPAN-2 [nTPM]":"26.3","Cell RNA - Daudi [nTPM]":"4.3","Cell RNA - EFO-21 [nTPM]":"21.9","Cell RNA - fHDF\/TERT166 [nTPM]":"34.2","Cell RNA - GAMG [nTPM]":"14.3","Cell RNA - HaCaT [nTPM]":"23.7","Cell RNA - HAP1 [nTPM]":"16.9","Cell RNA - HBEC3-KT [nTPM]":"24.6","Cell RNA - HBF TERT88 [nTPM]":"22.5","Cell RNA - HDLM-2 [nTPM]":"85.5","Cell RNA - HEK 293 [nTPM]":"29.1","Cell RNA - HEL [nTPM]":"11.1","Cell RNA - HeLa [nTPM]":"48.1","Cell RNA - Hep G2 [nTPM]":"24.6","Cell RNA - HHSteC [nTPM]":"38.4","Cell RNA - HL-60 [nTPM]":"16.4","Cell RNA - HMC-1 [nTPM]":"27.1","Cell RNA - HSkMC [nTPM]":"34.1","Cell RNA - hTCEpi [nTPM]":"15.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"24.6","Cell RNA - hTERT-HME1 [nTPM]":"14.5","Cell RNA - hTERT-RPE1 [nTPM]":"28.3","Cell RNA - HUVEC TERT2 [nTPM]":"34.9","Cell RNA - JURKAT [nTPM]":"14.1","Cell RNA - K-562 [nTPM]":"20.3","Cell RNA - Karpas-707 [nTPM]":"33.9","Cell RNA - LHCN-M2 [nTPM]":"31.5","Cell RNA - MCF7 [nTPM]":"26.8","Cell RNA - MOLT-4 [nTPM]":"13.4","Cell RNA - NB-4 [nTPM]":"14.2","Cell RNA - NTERA-2 [nTPM]":"21.5","Cell RNA - OE19 [nTPM]":"24.8","Cell RNA - PC-3 [nTPM]":"20.0","Cell RNA - REH [nTPM]":"10.8","Cell RNA - RH-30 [nTPM]":"43.1","Cell RNA - RPMI-8226 [nTPM]":"36.2","Cell RNA - RPTEC TERT1 [nTPM]":"34.9","Cell RNA - RT4 [nTPM]":"37.6","Cell RNA - SCLC-21H [nTPM]":"16.7","Cell RNA - SH-SY5Y [nTPM]":"26.0","Cell RNA - SiHa [nTPM]":"36.8","Cell RNA - SK-BR-3 [nTPM]":"80.1","Cell RNA - SK-MEL-30 [nTPM]":"19.2","Cell RNA - SuSa [nTPM]":"16.3","Cell RNA - T-47d [nTPM]":"49.0","Cell RNA - THP-1 [nTPM]":"14.0","Cell RNA - TIME [nTPM]":"21.0","Cell RNA - U-138 MG [nTPM]":"23.9","Cell RNA - U-2 OS [nTPM]":"19.8","Cell RNA - U-2197 [nTPM]":"31.4","Cell RNA - U-251 MG [nTPM]":"38.4","Cell RNA - U-266\/70 [nTPM]":"28.1","Cell RNA - U-266\/84 [nTPM]":"40.0","Cell RNA - U-698 [nTPM]":"3.6","Cell RNA - U-87 MG [nTPM]":"35.0","Cell RNA - U-937 [nTPM]":"8.2","Cell RNA - WM-115 [nTPM]":"37.6","Blood RNA - basophil [nTPM]":"12.5","Blood RNA - classical monocyte [nTPM]":"16.9","Blood RNA - eosinophil [nTPM]":"7.2","Blood RNA - gdT-cell [nTPM]":"12.3","Blood RNA - intermediate monocyte [nTPM]":"69.9","Blood RNA - MAIT T-cell [nTPM]":"9.4","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"7.6","Blood RNA - memory CD8 T-cell [nTPM]":"11.1","Blood RNA - myeloid DC [nTPM]":"15.1","Blood RNA - naive B-cell [nTPM]":"1.5","Blood RNA - naive CD4 T-cell [nTPM]":"6.6","Blood RNA - naive CD8 T-cell [nTPM]":"5.7","Blood RNA - neutrophil [nTPM]":"2.8","Blood RNA - NK-cell [nTPM]":"9.7","Blood RNA - non-classical monocyte [nTPM]":"48.2","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"8.3","Blood RNA - total PBMC [nTPM]":"10.9","Brain RNA - amygdala [nTPM]":"17.3","Brain RNA - basal ganglia [nTPM]":"17.1","Brain RNA - cerebellum [nTPM]":"17.0","Brain RNA - cerebral cortex [nTPM]":"18.5","Brain RNA - hippocampal formation [nTPM]":"19.8","Brain RNA - hypothalamus [nTPM]":"26.0","Brain RNA - medulla oblongata [nTPM]":"20.8","Brain RNA - midbrain [nTPM]":"19.6","Brain RNA - pons [nTPM]":"23.1","Brain RNA - spinal cord [nTPM]":"16.9","Brain RNA - thalamus [nTPM]":"22.0","Brain RNA - white matter [nTPM]":"17.2","Single Cell Type RNA - Adipocytes [nTPM]":"13.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.6","Single Cell Type RNA - Astrocytes [nTPM]":"6.2","Single Cell Type RNA - B-cells [nTPM]":"5.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"42.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"14.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"29.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"41.3","Single Cell Type RNA - dendritic cells [nTPM]":"2.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"37.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"50.6","Single Cell Type RNA - Early spermatids [nTPM]":"1.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.6","Single Cell Type RNA - Endothelial cells [nTPM]":"18.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.0","Single Cell Type RNA - Erythroid cells [nTPM]":"13.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"60.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"33.3","Single Cell Type RNA - Fibroblasts [nTPM]":"15.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.1","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"10.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"45.7","Single Cell Type RNA - Hepatocytes [nTPM]":"89.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"113.5","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.7","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"80.0","Single Cell Type RNA - Langerhans cells [nTPM]":"3.9","Single Cell Type RNA - Late spermatids [nTPM]":"3.5","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"33.8","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"29.8","Single Cell Type RNA - Muller glia cells [nTPM]":"20.6","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"33.5","Single Cell Type RNA - Paneth cells [nTPM]":"29.5","Single Cell Type RNA - Peritubular cells [nTPM]":"10.5","Single Cell Type RNA - Plasma cells [nTPM]":"21.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"55.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"33.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.9","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.5","Single Cell Type RNA - Spermatocytes [nTPM]":"11.8","Single Cell Type RNA - Spermatogonia [nTPM]":"19.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"29.3","Single Cell Type RNA - T-cells [nTPM]":"5.8","Single Cell Type RNA - Theca cells [nTPM]":"25.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.3","Single Cell Type RNA - Urothelial cells [nTPM]":"8.6"},{"Gene":"ACP4","Gene synonym":["ACPT"],"Ensembl":"ENSG00000142513","Gene description":"Acid phosphatase 4","Uniprot":["Q9BZG2"],"Chromosome":"19","Position":"50790415-50795219","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Amelogenesis imperfecta","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"1.2","testis":"3.7"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEK 293":"1.5","U-266\/84":"2.0"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.8","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"1.2","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"3.7","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.5","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.7","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.5","Cell RNA - HEK 293 [nTPM]":"1.5","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.9","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.5","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"2.0","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.8","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"ACP5","Gene synonym":["HPAP","TRAP"],"Ensembl":"ENSG00000102575","Gene description":"Acid phosphatase 5, tartrate resistant","Uniprot":["P13686"],"Chromosome":"19","Position":"11574660-11579008","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"174.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatic stellate cells":"426.9","Hofbauer cells":"426.7","Macrophages":"298.2","Proximal tubular cells":"145.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"200.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"41.1","K-562":"30.4","RPMI-8226":"41.4","SK-MEL-30":"127.6","U-138 MG":"102.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002584","HPA057655","HPA059463"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4000000","Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB002584":"AB_564039","HPA057655":"AB_2683490","HPA059463":"AB_2684028"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.4","Tissue RNA - adrenal gland [nTPM]":"6.0","Tissue RNA - amygdala [nTPM]":"2.2","Tissue RNA - appendix [nTPM]":"42.4","Tissue RNA - basal ganglia [nTPM]":"3.9","Tissue RNA - bone marrow [nTPM]":"9.4","Tissue RNA - breast [nTPM]":"25.6","Tissue RNA - cerebellum [nTPM]":"2.5","Tissue RNA - cerebral cortex [nTPM]":"21.4","Tissue RNA - cervix [nTPM]":"34.7","Tissue RNA - choroid plexus [nTPM]":"3.0","Tissue RNA - colon [nTPM]":"46.4","Tissue RNA - duodenum [nTPM]":"31.9","Tissue RNA - endometrium 1 [nTPM]":"19.2","Tissue RNA - epididymis [nTPM]":"7.8","Tissue RNA - esophagus [nTPM]":"23.4","Tissue RNA - fallopian tube [nTPM]":"8.6","Tissue RNA - gallbladder [nTPM]":"26.7","Tissue RNA - heart muscle [nTPM]":"5.1","Tissue RNA - hippocampal formation [nTPM]":"1.9","Tissue RNA - hypothalamus [nTPM]":"3.9","Tissue RNA - kidney [nTPM]":"74.0","Tissue RNA - liver [nTPM]":"32.5","Tissue RNA - lung [nTPM]":"174.1","Tissue RNA - lymph node [nTPM]":"87.1","Tissue RNA - medulla oblongata [nTPM]":"4.1","Tissue RNA - midbrain [nTPM]":"3.1","Tissue RNA - ovary [nTPM]":"20.3","Tissue RNA - pancreas [nTPM]":"11.9","Tissue RNA - parathyroid gland [nTPM]":"2.4","Tissue RNA - pituitary gland [nTPM]":"1.3","Tissue RNA - placenta [nTPM]":"13.3","Tissue RNA - pons [nTPM]":"6.0","Tissue RNA - prostate [nTPM]":"19.6","Tissue RNA - rectum [nTPM]":"36.4","Tissue RNA - retina [nTPM]":"20.1","Tissue RNA - salivary gland [nTPM]":"14.3","Tissue RNA - seminal vesicle [nTPM]":"7.0","Tissue RNA - skeletal muscle [nTPM]":"1.4","Tissue RNA - skin 1 [nTPM]":"24.9","Tissue RNA - small intestine [nTPM]":"30.2","Tissue RNA - smooth muscle [nTPM]":"13.3","Tissue RNA - spinal cord [nTPM]":"4.1","Tissue RNA - spleen [nTPM]":"43.5","Tissue RNA - stomach 1 [nTPM]":"38.7","Tissue RNA - testis [nTPM]":"4.0","Tissue RNA - thalamus [nTPM]":"15.7","Tissue RNA - thymus [nTPM]":"25.4","Tissue RNA - thyroid gland [nTPM]":"3.0","Tissue RNA - tongue [nTPM]":"5.0","Tissue RNA - tonsil [nTPM]":"43.6","Tissue RNA - urinary bladder [nTPM]":"33.1","Tissue RNA - vagina [nTPM]":"11.3","Tissue RNA - white matter [nTPM]":"5.7","Cell RNA - A-431 [nTPM]":"10.2","Cell RNA - A549 [nTPM]":"1.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.5","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"41.1","Cell RNA - BJ [nTPM]":"1.1","Cell RNA - BJ hTERT+ [nTPM]":"25.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"1.4","Cell RNA - EFO-21 [nTPM]":"1.8","Cell RNA - fHDF\/TERT166 [nTPM]":"9.0","Cell RNA - GAMG [nTPM]":"5.9","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"4.5","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"12.1","Cell RNA - HEK 293 [nTPM]":"0.8","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"5.0","Cell RNA - HHSteC [nTPM]":"1.4","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"4.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.4","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"30.4","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"2.3","Cell RNA - MOLT-4 [nTPM]":"0.9","Cell RNA - NB-4 [nTPM]":"1.4","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"0.7","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"1.8","Cell RNA - RPMI-8226 [nTPM]":"41.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"1.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"127.6","Cell RNA - SuSa [nTPM]":"1.1","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"0.9","Cell RNA - U-138 MG [nTPM]":"102.9","Cell RNA - U-2 OS [nTPM]":"1.2","Cell RNA - U-2197 [nTPM]":"1.8","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"5.7","Cell RNA - U-698 [nTPM]":"0.6","Cell RNA - U-87 MG [nTPM]":"23.7","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"4.0","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"35.3","Blood RNA - eosinophil [nTPM]":"76.6","Blood RNA - gdT-cell [nTPM]":"15.8","Blood RNA - intermediate monocyte [nTPM]":"36.1","Blood RNA - MAIT T-cell [nTPM]":"8.8","Blood RNA - memory B-cell [nTPM]":"200.1","Blood RNA - memory CD4 T-cell [nTPM]":"26.0","Blood RNA - memory CD8 T-cell [nTPM]":"19.6","Blood RNA - myeloid DC [nTPM]":"7.3","Blood RNA - naive B-cell [nTPM]":"110.9","Blood RNA - naive CD4 T-cell [nTPM]":"35.3","Blood RNA - naive CD8 T-cell [nTPM]":"20.2","Blood RNA - neutrophil [nTPM]":"10.4","Blood RNA - NK-cell [nTPM]":"13.3","Blood RNA - non-classical monocyte [nTPM]":"36.3","Blood RNA - plasmacytoid DC [nTPM]":"62.5","Blood RNA - T-reg [nTPM]":"67.8","Blood RNA - total PBMC [nTPM]":"36.4","Brain RNA - amygdala [nTPM]":"2.2","Brain RNA - basal ganglia [nTPM]":"3.9","Brain RNA - cerebellum [nTPM]":"2.5","Brain RNA - cerebral cortex [nTPM]":"21.4","Brain RNA - hippocampal formation [nTPM]":"1.9","Brain RNA - hypothalamus [nTPM]":"3.9","Brain RNA - medulla oblongata [nTPM]":"4.1","Brain RNA - midbrain [nTPM]":"3.1","Brain RNA - pons [nTPM]":"6.0","Brain RNA - spinal cord [nTPM]":"4.1","Brain RNA - thalamus [nTPM]":"15.7","Brain RNA - white matter [nTPM]":"5.7","Single Cell Type RNA - Adipocytes [nTPM]":"2.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"75.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.0","Single Cell Type RNA - Bipolar cells [nTPM]":"18.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"5.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"33.4","Single Cell Type RNA - dendritic cells [nTPM]":"21.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"1.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.1","Single Cell Type RNA - Endothelial cells [nTPM]":"30.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"24.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"32.7","Single Cell Type RNA - Fibroblasts [nTPM]":"19.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.9","Single Cell Type RNA - granulocytes [nTPM]":"63.7","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"426.9","Single Cell Type RNA - Hepatocytes [nTPM]":"8.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"426.7","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.7","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"106.0","Single Cell Type RNA - Langerhans cells [nTPM]":"68.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"298.2","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"79.8","Single Cell Type RNA - Muller glia cells [nTPM]":"48.5","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.4","Single Cell Type RNA - Paneth cells [nTPM]":"20.4","Single Cell Type RNA - Peritubular cells [nTPM]":"12.0","Single Cell Type RNA - Plasma cells [nTPM]":"33.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"145.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"41.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"26.1","Single Cell Type RNA - T-cells [nTPM]":"29.5","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.7","Single Cell Type RNA - Urothelial cells [nTPM]":"6.1"},{"Gene":"ACSF3","Gene synonym":[],"Ensembl":"ENSG00000176715","Gene description":"Acyl-CoA synthetase family member 3","Uniprot":["Q4G176"],"Chromosome":"16","Position":"89088375-89164121","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Ligase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"JURKAT":"242.9","U-698":"113.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008322"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA008322":"AB_1845294"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.76e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.97e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-3"},"Tissue RNA - adipose tissue [nTPM]":"8.9","Tissue RNA - adrenal gland [nTPM]":"20.5","Tissue RNA - amygdala [nTPM]":"8.0","Tissue RNA - appendix [nTPM]":"15.9","Tissue RNA - basal ganglia [nTPM]":"8.2","Tissue RNA - bone marrow [nTPM]":"11.6","Tissue RNA - breast [nTPM]":"9.4","Tissue RNA - cerebellum [nTPM]":"9.9","Tissue RNA - cerebral cortex [nTPM]":"11.4","Tissue RNA - cervix [nTPM]":"9.2","Tissue RNA - choroid plexus [nTPM]":"9.6","Tissue RNA - colon [nTPM]":"17.1","Tissue RNA - duodenum [nTPM]":"30.7","Tissue RNA - endometrium 1 [nTPM]":"9.6","Tissue RNA - epididymis [nTPM]":"9.7","Tissue RNA - esophagus [nTPM]":"10.5","Tissue RNA - fallopian tube [nTPM]":"9.5","Tissue RNA - gallbladder [nTPM]":"9.7","Tissue RNA - heart muscle [nTPM]":"9.8","Tissue RNA - hippocampal formation [nTPM]":"8.0","Tissue RNA - hypothalamus [nTPM]":"7.1","Tissue RNA - kidney [nTPM]":"11.6","Tissue RNA - liver [nTPM]":"19.2","Tissue RNA - lung [nTPM]":"7.9","Tissue RNA - lymph node [nTPM]":"21.7","Tissue RNA - medulla oblongata [nTPM]":"9.1","Tissue RNA - midbrain [nTPM]":"8.2","Tissue RNA - ovary [nTPM]":"8.9","Tissue RNA - pancreas [nTPM]":"15.6","Tissue RNA - parathyroid gland [nTPM]":"18.5","Tissue RNA - pituitary gland [nTPM]":"7.7","Tissue RNA - placenta [nTPM]":"6.1","Tissue RNA - pons [nTPM]":"9.3","Tissue RNA - prostate [nTPM]":"8.6","Tissue RNA - rectum [nTPM]":"11.4","Tissue RNA - retina [nTPM]":"5.9","Tissue RNA - salivary gland [nTPM]":"13.2","Tissue RNA - seminal vesicle [nTPM]":"6.5","Tissue RNA - skeletal muscle [nTPM]":"13.1","Tissue RNA - skin 1 [nTPM]":"10.5","Tissue RNA - small intestine [nTPM]":"26.4","Tissue RNA - smooth muscle [nTPM]":"7.8","Tissue RNA - spinal cord [nTPM]":"7.1","Tissue RNA - spleen [nTPM]":"13.3","Tissue RNA - stomach 1 [nTPM]":"12.6","Tissue RNA - testis [nTPM]":"7.8","Tissue RNA - thalamus [nTPM]":"10.6","Tissue RNA - thymus [nTPM]":"37.6","Tissue RNA - thyroid gland [nTPM]":"9.8","Tissue RNA - tongue [nTPM]":"16.5","Tissue RNA - tonsil [nTPM]":"13.9","Tissue RNA - urinary bladder [nTPM]":"10.2","Tissue RNA - vagina [nTPM]":"8.7","Tissue RNA - white matter [nTPM]":"12.0","Cell RNA - A-431 [nTPM]":"12.8","Cell RNA - A549 [nTPM]":"17.8","Cell RNA - AF22 [nTPM]":"8.4","Cell RNA - AN3-CA [nTPM]":"14.4","Cell RNA - ASC diff [nTPM]":"14.5","Cell RNA - ASC TERT1 [nTPM]":"13.3","Cell RNA - BEWO [nTPM]":"19.6","Cell RNA - BJ [nTPM]":"16.5","Cell RNA - BJ hTERT+ [nTPM]":"6.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.4","Cell RNA - CACO-2 [nTPM]":"16.2","Cell RNA - CAPAN-2 [nTPM]":"20.9","Cell RNA - Daudi [nTPM]":"33.2","Cell RNA - EFO-21 [nTPM]":"21.5","Cell RNA - fHDF\/TERT166 [nTPM]":"14.2","Cell RNA - GAMG [nTPM]":"10.5","Cell RNA - HaCaT [nTPM]":"20.9","Cell RNA - HAP1 [nTPM]":"8.6","Cell RNA - HBEC3-KT [nTPM]":"19.4","Cell RNA - HBF TERT88 [nTPM]":"10.0","Cell RNA - HDLM-2 [nTPM]":"12.3","Cell RNA - HEK 293 [nTPM]":"20.6","Cell RNA - HEL [nTPM]":"25.8","Cell RNA - HeLa [nTPM]":"16.6","Cell RNA - Hep G2 [nTPM]":"23.8","Cell RNA - HHSteC [nTPM]":"35.2","Cell RNA - HL-60 [nTPM]":"8.1","Cell RNA - HMC-1 [nTPM]":"13.3","Cell RNA - HSkMC [nTPM]":"19.4","Cell RNA - hTCEpi [nTPM]":"22.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.4","Cell RNA - hTERT-HME1 [nTPM]":"18.1","Cell RNA - hTERT-RPE1 [nTPM]":"18.5","Cell RNA - HUVEC TERT2 [nTPM]":"11.7","Cell RNA - JURKAT [nTPM]":"242.9","Cell RNA - K-562 [nTPM]":"36.4","Cell RNA - Karpas-707 [nTPM]":"10.1","Cell RNA - LHCN-M2 [nTPM]":"9.0","Cell RNA - MCF7 [nTPM]":"32.7","Cell RNA - MOLT-4 [nTPM]":"45.6","Cell RNA - NB-4 [nTPM]":"25.7","Cell RNA - NTERA-2 [nTPM]":"9.8","Cell RNA - OE19 [nTPM]":"24.8","Cell RNA - PC-3 [nTPM]":"30.0","Cell RNA - REH [nTPM]":"53.2","Cell RNA - RH-30 [nTPM]":"7.2","Cell RNA - RPMI-8226 [nTPM]":"14.1","Cell RNA - RPTEC TERT1 [nTPM]":"15.9","Cell RNA - RT4 [nTPM]":"17.2","Cell RNA - SCLC-21H [nTPM]":"20.6","Cell RNA - SH-SY5Y [nTPM]":"15.3","Cell RNA - SiHa [nTPM]":"26.6","Cell RNA - SK-BR-3 [nTPM]":"6.8","Cell RNA - SK-MEL-30 [nTPM]":"26.2","Cell RNA - SuSa [nTPM]":"13.5","Cell RNA - T-47d [nTPM]":"23.1","Cell RNA - THP-1 [nTPM]":"28.6","Cell RNA - TIME [nTPM]":"11.6","Cell RNA - U-138 MG [nTPM]":"17.3","Cell RNA - U-2 OS [nTPM]":"12.8","Cell RNA - U-2197 [nTPM]":"10.2","Cell RNA - U-251 MG [nTPM]":"12.5","Cell RNA - U-266\/70 [nTPM]":"11.7","Cell RNA - U-266\/84 [nTPM]":"17.3","Cell RNA - U-698 [nTPM]":"113.0","Cell RNA - U-87 MG [nTPM]":"15.4","Cell RNA - U-937 [nTPM]":"29.8","Cell RNA - WM-115 [nTPM]":"14.5","Blood RNA - basophil [nTPM]":"7.0","Blood RNA - classical monocyte [nTPM]":"23.0","Blood RNA - eosinophil [nTPM]":"17.2","Blood RNA - gdT-cell [nTPM]":"22.7","Blood RNA - intermediate monocyte [nTPM]":"22.8","Blood RNA - MAIT T-cell [nTPM]":"25.2","Blood RNA - memory B-cell [nTPM]":"29.8","Blood RNA - memory CD4 T-cell [nTPM]":"18.5","Blood RNA - memory CD8 T-cell [nTPM]":"16.5","Blood RNA - myeloid DC [nTPM]":"21.7","Blood RNA - naive B-cell [nTPM]":"20.6","Blood RNA - naive CD4 T-cell [nTPM]":"19.5","Blood RNA - naive CD8 T-cell [nTPM]":"17.4","Blood RNA - neutrophil [nTPM]":"9.0","Blood RNA - NK-cell [nTPM]":"10.8","Blood RNA - non-classical monocyte [nTPM]":"21.3","Blood RNA - plasmacytoid DC [nTPM]":"24.6","Blood RNA - T-reg [nTPM]":"19.6","Blood RNA - total PBMC [nTPM]":"17.9","Brain RNA - amygdala [nTPM]":"8.0","Brain RNA - basal ganglia [nTPM]":"8.2","Brain RNA - cerebellum [nTPM]":"9.9","Brain RNA - cerebral cortex [nTPM]":"11.4","Brain RNA - hippocampal formation [nTPM]":"8.0","Brain RNA - hypothalamus [nTPM]":"7.1","Brain RNA - medulla oblongata [nTPM]":"9.1","Brain RNA - midbrain [nTPM]":"8.2","Brain RNA - pons [nTPM]":"9.3","Brain RNA - spinal cord [nTPM]":"7.1","Brain RNA - thalamus [nTPM]":"10.6","Brain RNA - white matter [nTPM]":"12.0","Single Cell Type RNA - Adipocytes [nTPM]":"9.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.4","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"22.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"20.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"15.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.9","Single Cell Type RNA - dendritic cells [nTPM]":"17.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"29.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"16.1","Single Cell Type RNA - Early spermatids [nTPM]":"13.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.3","Single Cell Type RNA - Endothelial cells [nTPM]":"10.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.8","Single Cell Type RNA - Erythroid cells [nTPM]":"14.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.8","Single Cell Type RNA - Fibroblasts [nTPM]":"9.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.1","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"44.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"12.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.6","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.4","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"19.5","Single Cell Type RNA - Langerhans cells [nTPM]":"14.2","Single Cell Type RNA - Late spermatids [nTPM]":"20.4","Single Cell Type RNA - Leydig cells [nTPM]":"12.2","Single Cell Type RNA - Macrophages [nTPM]":"14.0","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"18.6","Single Cell Type RNA - Muller glia cells [nTPM]":"9.3","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.3","Single Cell Type RNA - Paneth cells [nTPM]":"20.8","Single Cell Type RNA - Peritubular cells [nTPM]":"10.1","Single Cell Type RNA - Plasma cells [nTPM]":"21.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"54.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.0","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.7","Single Cell Type RNA - Spermatocytes [nTPM]":"8.8","Single Cell Type RNA - Spermatogonia [nTPM]":"8.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.3","Single Cell Type RNA - T-cells [nTPM]":"17.0","Single Cell Type RNA - Theca cells [nTPM]":"20.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"31.1","Single Cell Type RNA - Urothelial cells [nTPM]":"7.4"},{"Gene":"ACSL4","Gene synonym":["ACS4","FACL4","LACS4","MRX63","MRX68"],"Ensembl":"ENSG00000068366","Gene description":"Acyl-CoA synthetase long chain family member 4","Uniprot":["O60488"],"Chromosome":"X","Position":"109624244-109733403","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Ligase"],"Disease involvement":["Alport syndrome","Deafness","Disease variant","Elliptocytosis","Hereditary hemolytic anemia","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"184.3","Glandular and luminal cells":"208.8","granulocytes":"633.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"360.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000286","HPA005552"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"16000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 60: Granulocytes - Receptor signaling","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"HPA000286":"AB_2665966","HPA005552":"AB_1078774"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.73e-4"},"Tissue RNA - adipose tissue [nTPM]":"44.2","Tissue RNA - adrenal gland [nTPM]":"40.6","Tissue RNA - amygdala [nTPM]":"11.9","Tissue RNA - appendix [nTPM]":"38.8","Tissue RNA - basal ganglia [nTPM]":"14.1","Tissue RNA - bone marrow [nTPM]":"16.2","Tissue RNA - breast [nTPM]":"19.8","Tissue RNA - cerebellum [nTPM]":"13.2","Tissue RNA - cerebral cortex [nTPM]":"14.8","Tissue RNA - cervix [nTPM]":"48.2","Tissue RNA - choroid plexus [nTPM]":"5.6","Tissue RNA - colon [nTPM]":"12.7","Tissue RNA - duodenum [nTPM]":"15.4","Tissue RNA - endometrium 1 [nTPM]":"19.2","Tissue RNA - epididymis [nTPM]":"17.7","Tissue RNA - esophagus [nTPM]":"15.8","Tissue RNA - fallopian tube [nTPM]":"13.4","Tissue RNA - gallbladder [nTPM]":"29.2","Tissue RNA - heart muscle [nTPM]":"29.4","Tissue RNA - hippocampal formation [nTPM]":"16.5","Tissue RNA - hypothalamus [nTPM]":"23.7","Tissue RNA - kidney [nTPM]":"46.4","Tissue RNA - liver [nTPM]":"13.9","Tissue RNA - lung [nTPM]":"39.0","Tissue RNA - lymph node [nTPM]":"24.6","Tissue RNA - medulla oblongata [nTPM]":"17.6","Tissue RNA - midbrain [nTPM]":"20.8","Tissue RNA - ovary [nTPM]":"14.9","Tissue RNA - pancreas [nTPM]":"11.9","Tissue RNA - parathyroid gland [nTPM]":"19.8","Tissue RNA - pituitary gland [nTPM]":"9.2","Tissue RNA - placenta [nTPM]":"21.4","Tissue RNA - pons [nTPM]":"21.3","Tissue RNA - prostate [nTPM]":"13.4","Tissue RNA - rectum [nTPM]":"13.6","Tissue RNA - retina [nTPM]":"24.7","Tissue RNA - salivary gland [nTPM]":"10.6","Tissue RNA - seminal vesicle [nTPM]":"15.2","Tissue RNA - skeletal muscle [nTPM]":"42.6","Tissue RNA - skin 1 [nTPM]":"9.9","Tissue RNA - small intestine [nTPM]":"13.4","Tissue RNA - smooth muscle [nTPM]":"22.0","Tissue RNA - spinal cord [nTPM]":"13.7","Tissue RNA - spleen [nTPM]":"22.2","Tissue RNA - stomach 1 [nTPM]":"19.3","Tissue RNA - testis [nTPM]":"26.8","Tissue RNA - thalamus [nTPM]":"14.6","Tissue RNA - thymus [nTPM]":"20.3","Tissue RNA - thyroid gland [nTPM]":"18.6","Tissue RNA - tongue [nTPM]":"16.9","Tissue RNA - tonsil [nTPM]":"18.5","Tissue RNA - urinary bladder [nTPM]":"68.0","Tissue RNA - vagina [nTPM]":"10.6","Tissue RNA - white matter [nTPM]":"18.9","Cell RNA - A-431 [nTPM]":"67.3","Cell RNA - A549 [nTPM]":"21.3","Cell RNA - AF22 [nTPM]":"24.2","Cell RNA - AN3-CA [nTPM]":"28.3","Cell RNA - ASC diff [nTPM]":"97.8","Cell RNA - ASC TERT1 [nTPM]":"61.6","Cell RNA - BEWO [nTPM]":"20.3","Cell RNA - BJ [nTPM]":"94.0","Cell RNA - BJ hTERT+ [nTPM]":"107.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"91.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"97.4","Cell RNA - CACO-2 [nTPM]":"21.1","Cell RNA - CAPAN-2 [nTPM]":"45.0","Cell RNA - Daudi [nTPM]":"46.2","Cell RNA - EFO-21 [nTPM]":"35.4","Cell RNA - fHDF\/TERT166 [nTPM]":"71.7","Cell RNA - GAMG [nTPM]":"100.9","Cell RNA - HaCaT [nTPM]":"19.4","Cell RNA - HAP1 [nTPM]":"22.4","Cell RNA - HBEC3-KT [nTPM]":"92.0","Cell RNA - HBF TERT88 [nTPM]":"143.0","Cell RNA - HDLM-2 [nTPM]":"15.7","Cell RNA - HEK 293 [nTPM]":"23.3","Cell RNA - HEL [nTPM]":"181.4","Cell RNA - HeLa [nTPM]":"26.6","Cell RNA - Hep G2 [nTPM]":"223.3","Cell RNA - HHSteC [nTPM]":"44.8","Cell RNA - HL-60 [nTPM]":"44.8","Cell RNA - HMC-1 [nTPM]":"360.0","Cell RNA - HSkMC [nTPM]":"51.4","Cell RNA - hTCEpi [nTPM]":"36.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"103.6","Cell RNA - hTERT-HME1 [nTPM]":"74.0","Cell RNA - hTERT-RPE1 [nTPM]":"50.2","Cell RNA - HUVEC TERT2 [nTPM]":"71.8","Cell RNA - JURKAT [nTPM]":"25.5","Cell RNA - K-562 [nTPM]":"5.6","Cell RNA - Karpas-707 [nTPM]":"54.2","Cell RNA - LHCN-M2 [nTPM]":"100.7","Cell RNA - MCF7 [nTPM]":"4.7","Cell RNA - MOLT-4 [nTPM]":"40.7","Cell RNA - NB-4 [nTPM]":"60.7","Cell RNA - NTERA-2 [nTPM]":"31.6","Cell RNA - OE19 [nTPM]":"15.2","Cell RNA - PC-3 [nTPM]":"37.2","Cell RNA - REH [nTPM]":"26.4","Cell RNA - RH-30 [nTPM]":"45.4","Cell RNA - RPMI-8226 [nTPM]":"39.6","Cell RNA - RPTEC TERT1 [nTPM]":"136.3","Cell RNA - RT4 [nTPM]":"20.9","Cell RNA - SCLC-21H [nTPM]":"15.2","Cell RNA - SH-SY5Y [nTPM]":"12.3","Cell RNA - SiHa [nTPM]":"109.3","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"63.2","Cell RNA - SuSa [nTPM]":"49.0","Cell RNA - T-47d [nTPM]":"1.9","Cell RNA - THP-1 [nTPM]":"45.8","Cell RNA - TIME [nTPM]":"128.5","Cell RNA - U-138 MG [nTPM]":"81.1","Cell RNA - U-2 OS [nTPM]":"22.6","Cell RNA - U-2197 [nTPM]":"129.3","Cell RNA - U-251 MG [nTPM]":"85.9","Cell RNA - U-266\/70 [nTPM]":"28.1","Cell RNA - U-266\/84 [nTPM]":"31.7","Cell RNA - U-698 [nTPM]":"41.2","Cell RNA - U-87 MG [nTPM]":"139.7","Cell RNA - U-937 [nTPM]":"97.8","Cell RNA - WM-115 [nTPM]":"52.2","Blood RNA - basophil [nTPM]":"32.5","Blood RNA - classical monocyte [nTPM]":"10.9","Blood RNA - eosinophil [nTPM]":"35.0","Blood RNA - gdT-cell [nTPM]":"4.2","Blood RNA - intermediate monocyte [nTPM]":"15.5","Blood RNA - MAIT T-cell [nTPM]":"3.2","Blood RNA - memory B-cell [nTPM]":"3.3","Blood RNA - memory CD4 T-cell [nTPM]":"3.9","Blood RNA - memory CD8 T-cell [nTPM]":"3.5","Blood RNA - myeloid DC [nTPM]":"10.6","Blood RNA - naive B-cell [nTPM]":"3.1","Blood RNA - naive CD4 T-cell [nTPM]":"3.0","Blood RNA - naive CD8 T-cell [nTPM]":"3.8","Blood RNA - neutrophil [nTPM]":"29.6","Blood RNA - NK-cell [nTPM]":"4.0","Blood RNA - non-classical monocyte [nTPM]":"19.4","Blood RNA - plasmacytoid DC [nTPM]":"4.0","Blood RNA - T-reg [nTPM]":"6.7","Blood RNA - total PBMC [nTPM]":"6.5","Brain RNA - amygdala [nTPM]":"11.9","Brain RNA - basal ganglia [nTPM]":"14.1","Brain RNA - cerebellum [nTPM]":"13.2","Brain RNA - cerebral cortex [nTPM]":"14.8","Brain RNA - hippocampal formation [nTPM]":"16.5","Brain RNA - hypothalamus [nTPM]":"23.7","Brain RNA - medulla oblongata [nTPM]":"17.6","Brain RNA - midbrain [nTPM]":"20.8","Brain RNA - pons [nTPM]":"21.3","Brain RNA - spinal cord [nTPM]":"13.7","Brain RNA - thalamus [nTPM]":"14.6","Brain RNA - white matter [nTPM]":"18.9","Single Cell Type RNA - Adipocytes [nTPM]":"27.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"76.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"184.3","Single Cell Type RNA - Astrocytes [nTPM]":"29.0","Single Cell Type RNA - B-cells [nTPM]":"19.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"22.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"25.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"20.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"81.4","Single Cell Type RNA - Bipolar cells [nTPM]":"44.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"37.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"40.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"73.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.3","Single Cell Type RNA - dendritic cells [nTPM]":"18.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"50.9","Single Cell Type RNA - Ductal cells [nTPM]":"27.7","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"79.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"27.0","Single Cell Type RNA - Endothelial cells [nTPM]":"29.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.7","Single Cell Type RNA - Erythroid cells [nTPM]":"26.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"76.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"36.9","Single Cell Type RNA - Fibroblasts [nTPM]":"46.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"208.8","Single Cell Type RNA - granulocytes [nTPM]":"633.8","Single Cell Type RNA - Granulosa cells [nTPM]":"151.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.2","Single Cell Type RNA - Hepatocytes [nTPM]":"44.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.9","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"78.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.7","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"64.9","Single Cell Type RNA - Langerhans cells [nTPM]":"59.1","Single Cell Type RNA - Late spermatids [nTPM]":"4.9","Single Cell Type RNA - Leydig cells [nTPM]":"5.6","Single Cell Type RNA - Macrophages [nTPM]":"67.8","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"57.1","Single Cell Type RNA - monocytes [nTPM]":"70.4","Single Cell Type RNA - Muller glia cells [nTPM]":"10.9","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"71.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"116.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"32.3","Single Cell Type RNA - Paneth cells [nTPM]":"3.0","Single Cell Type RNA - Peritubular cells [nTPM]":"10.1","Single Cell Type RNA - Plasma cells [nTPM]":"36.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.9","Single Cell Type RNA - Spermatocytes [nTPM]":"3.7","Single Cell Type RNA - Spermatogonia [nTPM]":"5.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"31.6","Single Cell Type RNA - T-cells [nTPM]":"25.2","Single Cell Type RNA - Theca cells [nTPM]":"34.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.7","Single Cell Type RNA - Urothelial cells [nTPM]":"18.4"},{"Gene":"ACSL6","Gene synonym":["ACS2","FACL6","KIAA0837","LACS2","LACS5"],"Ensembl":"ENSG00000164398","Gene description":"Acyl-CoA synthetase long chain family member 6","Uniprot":["Q9UKU0"],"Chromosome":"5","Position":"131949973-132012243","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Ligase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"22.6","brain":"32.0","retina":"45.8","testis":"20.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"229.2","Cone photoreceptor cells":"229.4","Erythroid cells":"110.5","Inhibitory neurons":"110.6","Rod photoreceptor cells":"130.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"colorectal cancer":"1.8","glioma":"1.9","liver cancer":"0.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory CD8 T-cell":"1.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"T-cells":"1.6"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"SCLC-21H":"7.6","U-937":"6.2"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040470"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA040470":"AB_10794033"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"4.2","Tissue RNA - amygdala [nTPM]":"14.8","Tissue RNA - appendix [nTPM]":"1.4","Tissue RNA - basal ganglia [nTPM]":"18.3","Tissue RNA - bone marrow [nTPM]":"22.6","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"26.3","Tissue RNA - cerebral cortex [nTPM]":"32.0","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"1.2","Tissue RNA - colon [nTPM]":"0.5","Tissue RNA - duodenum [nTPM]":"4.7","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"1.4","Tissue RNA - hippocampal formation [nTPM]":"18.6","Tissue RNA - hypothalamus [nTPM]":"12.8","Tissue RNA - kidney [nTPM]":"1.9","Tissue RNA - liver [nTPM]":"2.0","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"2.4","Tissue RNA - medulla oblongata [nTPM]":"22.2","Tissue RNA - midbrain [nTPM]":"18.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"1.1","Tissue RNA - parathyroid gland [nTPM]":"11.3","Tissue RNA - pituitary gland [nTPM]":"4.2","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"18.9","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"45.8","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"18.0","Tissue RNA - skeletal muscle [nTPM]":"2.3","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"2.4","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"13.8","Tissue RNA - spleen [nTPM]":"1.1","Tissue RNA - stomach 1 [nTPM]":"0.6","Tissue RNA - testis [nTPM]":"20.7","Tissue RNA - thalamus [nTPM]":"25.0","Tissue RNA - thymus [nTPM]":"0.6","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"1.4","Tissue RNA - tonsil [nTPM]":"1.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"14.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.7","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.9","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"1.5","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.7","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"1.3","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"1.0","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"7.6","Cell RNA - SH-SY5Y [nTPM]":"0.4","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.7","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"6.2","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"1.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.7","Blood RNA - memory CD8 T-cell [nTPM]":"1.6","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"14.8","Brain RNA - basal ganglia [nTPM]":"18.3","Brain RNA - cerebellum [nTPM]":"26.3","Brain RNA - cerebral cortex [nTPM]":"32.0","Brain RNA - hippocampal formation [nTPM]":"18.6","Brain RNA - hypothalamus [nTPM]":"12.8","Brain RNA - medulla oblongata [nTPM]":"22.2","Brain RNA - midbrain [nTPM]":"18.2","Brain RNA - pons [nTPM]":"18.9","Brain RNA - spinal cord [nTPM]":"13.8","Brain RNA - thalamus [nTPM]":"25.0","Brain RNA - white matter [nTPM]":"14.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.2","Single Cell Type RNA - Astrocytes [nTPM]":"229.2","Single Cell Type RNA - B-cells [nTPM]":"1.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"65.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"16.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"229.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"3.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.6","Single Cell Type RNA - Early spermatids [nTPM]":"43.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"3.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"110.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"70.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"4.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"10.1","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"8.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"110.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"15.9","Single Cell Type RNA - Late spermatids [nTPM]":"7.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"6.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"0.9","Single Cell Type RNA - Muller glia cells [nTPM]":"24.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"41.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"1.6","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"130.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.1","Single Cell Type RNA - Spermatocytes [nTPM]":"45.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"15.3","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"ACTN2","Gene synonym":[],"Ensembl":"ENSG00000077522","Gene description":"Actinin alpha 2","Uniprot":["P35609"],"Chromosome":"1","Position":"236664141-236764631","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":["Actin-binding"],"Disease involvement":["Cardiomyopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"53","RNA tissue specific nTPM":{"heart muscle":"772.7","skeletal muscle":"2134.7","tongue":"1262.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Cardiomyocytes":"1762.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"10.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+ SV40 Large T+ RasG12V":"2.0","HEK 293":"1.3","HSkMC":"5.9","hTEC\/SVTERT24-B":"2.7"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"66.6"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"basal ganglia":"44.5"},"Antibody":["HPA006035","HPA008315"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"25000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Actin filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA006035":"AB_1078095","HPA008315":"AB_1844543"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.7","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"12.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"26.3","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.9","Tissue RNA - cerebellum [nTPM]":"8.0","Tissue RNA - cerebral cortex [nTPM]":"20.1","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"11.0","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.5","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"21.8","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"0.7","Tissue RNA - heart muscle [nTPM]":"772.7","Tissue RNA - hippocampal formation [nTPM]":"13.2","Tissue RNA - hypothalamus [nTPM]":"12.1","Tissue RNA - kidney [nTPM]":"0.5","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"3.9","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"9.7","Tissue RNA - midbrain [nTPM]":"8.1","Tissue RNA - ovary [nTPM]":"1.1","Tissue RNA - pancreas [nTPM]":"1.6","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"10.7","Tissue RNA - prostate [nTPM]":"16.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"18.4","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"2134.7","Tissue RNA - skin 1 [nTPM]":"1.3","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"1.8","Tissue RNA - spinal cord [nTPM]":"8.0","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"3.8","Tissue RNA - testis [nTPM]":"4.2","Tissue RNA - thalamus [nTPM]":"8.7","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"1262.2","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"3.5","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"14.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.6","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.4","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"1.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"5.9","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.7","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.9","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.6","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.4","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"12.0","Brain RNA - basal ganglia [nTPM]":"26.3","Brain RNA - cerebellum [nTPM]":"8.0","Brain RNA - cerebral cortex [nTPM]":"20.1","Brain RNA - hippocampal formation [nTPM]":"13.2","Brain RNA - hypothalamus [nTPM]":"12.1","Brain RNA - medulla oblongata [nTPM]":"9.7","Brain RNA - midbrain [nTPM]":"8.1","Brain RNA - pons [nTPM]":"10.7","Brain RNA - spinal cord [nTPM]":"8.0","Brain RNA - thalamus [nTPM]":"8.7","Brain RNA - white matter [nTPM]":"14.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"18.6","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"2.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1762.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"8.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.2","Single Cell Type RNA - Endothelial cells [nTPM]":"10.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"40.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"43.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"24.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"1.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"24.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"156.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"66.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.4","Single Cell Type RNA - Spermatocytes [nTPM]":"3.1","Single Cell Type RNA - Spermatogonia [nTPM]":"2.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"ACVR1","Gene synonym":["ACVR1A","ACVRLK2","ALK2","SKR1"],"Ensembl":"ENSG00000115170","Gene description":"Activin A receptor type 1","Uniprot":["Q04771"],"Chromosome":"2","Position":"157736444-157876330","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Microglial cells":"106.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"6.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007505","HPA046514"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA007505":"AB_1844752","HPA046514":"AB_2732526"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.17e-4"},"Tissue RNA - adipose tissue [nTPM]":"20.8","Tissue RNA - adrenal gland [nTPM]":"10.4","Tissue RNA - amygdala [nTPM]":"17.3","Tissue RNA - appendix [nTPM]":"12.9","Tissue RNA - basal ganglia [nTPM]":"12.7","Tissue RNA - bone marrow [nTPM]":"1.8","Tissue RNA - breast [nTPM]":"18.8","Tissue RNA - cerebellum [nTPM]":"14.0","Tissue RNA - cerebral cortex [nTPM]":"15.4","Tissue RNA - cervix [nTPM]":"28.1","Tissue RNA - choroid plexus [nTPM]":"17.4","Tissue RNA - colon [nTPM]":"16.5","Tissue RNA - duodenum [nTPM]":"10.9","Tissue RNA - endometrium 1 [nTPM]":"24.4","Tissue RNA - epididymis [nTPM]":"32.7","Tissue RNA - esophagus [nTPM]":"11.3","Tissue RNA - fallopian tube [nTPM]":"17.0","Tissue RNA - gallbladder [nTPM]":"24.2","Tissue RNA - heart muscle [nTPM]":"19.7","Tissue RNA - hippocampal formation [nTPM]":"26.3","Tissue RNA - hypothalamus [nTPM]":"12.8","Tissue RNA - kidney [nTPM]":"26.4","Tissue RNA - liver [nTPM]":"22.7","Tissue RNA - lung [nTPM]":"17.5","Tissue RNA - lymph node [nTPM]":"8.8","Tissue RNA - medulla oblongata [nTPM]":"13.7","Tissue RNA - midbrain [nTPM]":"12.9","Tissue RNA - ovary [nTPM]":"21.2","Tissue RNA - pancreas [nTPM]":"10.0","Tissue RNA - parathyroid gland [nTPM]":"8.5","Tissue RNA - pituitary gland [nTPM]":"10.9","Tissue RNA - placenta [nTPM]":"17.6","Tissue RNA - pons [nTPM]":"13.7","Tissue RNA - prostate [nTPM]":"15.1","Tissue RNA - rectum [nTPM]":"12.6","Tissue RNA - retina [nTPM]":"6.3","Tissue RNA - salivary gland [nTPM]":"18.8","Tissue RNA - seminal vesicle [nTPM]":"15.3","Tissue RNA - skeletal muscle [nTPM]":"21.5","Tissue RNA - skin 1 [nTPM]":"13.9","Tissue RNA - small intestine [nTPM]":"10.5","Tissue RNA - smooth muscle [nTPM]":"34.5","Tissue RNA - spinal cord [nTPM]":"12.6","Tissue RNA - spleen [nTPM]":"8.3","Tissue RNA - stomach 1 [nTPM]":"14.7","Tissue RNA - testis [nTPM]":"5.2","Tissue RNA - thalamus [nTPM]":"16.3","Tissue RNA - thymus [nTPM]":"7.5","Tissue RNA - thyroid gland [nTPM]":"40.5","Tissue RNA - tongue [nTPM]":"13.3","Tissue RNA - tonsil [nTPM]":"8.2","Tissue RNA - urinary bladder [nTPM]":"20.9","Tissue RNA - vagina [nTPM]":"15.5","Tissue RNA - white matter [nTPM]":"11.8","Cell RNA - A-431 [nTPM]":"6.1","Cell RNA - A549 [nTPM]":"13.1","Cell RNA - AF22 [nTPM]":"14.4","Cell RNA - AN3-CA [nTPM]":"18.5","Cell RNA - ASC diff [nTPM]":"65.0","Cell RNA - ASC TERT1 [nTPM]":"70.6","Cell RNA - BEWO [nTPM]":"18.9","Cell RNA - BJ [nTPM]":"43.4","Cell RNA - BJ hTERT+ [nTPM]":"71.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"33.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"36.1","Cell RNA - CACO-2 [nTPM]":"10.1","Cell RNA - CAPAN-2 [nTPM]":"13.4","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"18.2","Cell RNA - fHDF\/TERT166 [nTPM]":"45.6","Cell RNA - GAMG [nTPM]":"32.3","Cell RNA - HaCaT [nTPM]":"16.9","Cell RNA - HAP1 [nTPM]":"10.5","Cell RNA - HBEC3-KT [nTPM]":"22.5","Cell RNA - HBF TERT88 [nTPM]":"36.8","Cell RNA - HDLM-2 [nTPM]":"43.0","Cell RNA - HEK 293 [nTPM]":"8.7","Cell RNA - HEL [nTPM]":"25.7","Cell RNA - HeLa [nTPM]":"7.2","Cell RNA - Hep G2 [nTPM]":"14.4","Cell RNA - HHSteC [nTPM]":"54.7","Cell RNA - HL-60 [nTPM]":"2.0","Cell RNA - HMC-1 [nTPM]":"28.5","Cell RNA - HSkMC [nTPM]":"89.5","Cell RNA - hTCEpi [nTPM]":"41.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"69.8","Cell RNA - hTERT-HME1 [nTPM]":"84.2","Cell RNA - hTERT-RPE1 [nTPM]":"42.8","Cell RNA - HUVEC TERT2 [nTPM]":"38.7","Cell RNA - JURKAT [nTPM]":"6.7","Cell RNA - K-562 [nTPM]":"9.5","Cell RNA - Karpas-707 [nTPM]":"6.7","Cell RNA - LHCN-M2 [nTPM]":"45.2","Cell RNA - MCF7 [nTPM]":"11.1","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"21.4","Cell RNA - OE19 [nTPM]":"8.7","Cell RNA - PC-3 [nTPM]":"21.7","Cell RNA - REH [nTPM]":"4.1","Cell RNA - RH-30 [nTPM]":"19.6","Cell RNA - RPMI-8226 [nTPM]":"5.7","Cell RNA - RPTEC TERT1 [nTPM]":"45.4","Cell RNA - RT4 [nTPM]":"24.5","Cell RNA - SCLC-21H [nTPM]":"12.4","Cell RNA - SH-SY5Y [nTPM]":"14.9","Cell RNA - SiHa [nTPM]":"17.0","Cell RNA - SK-BR-3 [nTPM]":"9.7","Cell RNA - SK-MEL-30 [nTPM]":"64.5","Cell RNA - SuSa [nTPM]":"22.2","Cell RNA - T-47d [nTPM]":"5.3","Cell RNA - THP-1 [nTPM]":"7.0","Cell RNA - TIME [nTPM]":"54.0","Cell RNA - U-138 MG [nTPM]":"50.9","Cell RNA - U-2 OS [nTPM]":"16.8","Cell RNA - U-2197 [nTPM]":"25.3","Cell RNA - U-251 MG [nTPM]":"17.1","Cell RNA - U-266\/70 [nTPM]":"4.7","Cell RNA - U-266\/84 [nTPM]":"3.5","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"52.2","Cell RNA - U-937 [nTPM]":"1.6","Cell RNA - WM-115 [nTPM]":"58.1","Blood RNA - basophil [nTPM]":"2.9","Blood RNA - classical monocyte [nTPM]":"1.7","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"4.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.3","Blood RNA - myeloid DC [nTPM]":"1.3","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"1.2","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"1.4","Blood RNA - T-reg [nTPM]":"6.6","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"17.3","Brain RNA - basal ganglia [nTPM]":"12.7","Brain RNA - cerebellum [nTPM]":"14.0","Brain RNA - cerebral cortex [nTPM]":"15.4","Brain RNA - hippocampal formation [nTPM]":"26.3","Brain RNA - hypothalamus [nTPM]":"12.8","Brain RNA - medulla oblongata [nTPM]":"13.7","Brain RNA - midbrain [nTPM]":"12.9","Brain RNA - pons [nTPM]":"13.7","Brain RNA - spinal cord [nTPM]":"12.6","Brain RNA - thalamus [nTPM]":"16.3","Brain RNA - white matter [nTPM]":"11.8","Single Cell Type RNA - Adipocytes [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.0","Single Cell Type RNA - Astrocytes [nTPM]":"22.9","Single Cell Type RNA - B-cells [nTPM]":"1.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Bipolar cells [nTPM]":"10.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"12.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.4","Single Cell Type RNA - dendritic cells [nTPM]":"1.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.9","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.9","Single Cell Type RNA - Endothelial cells [nTPM]":"17.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"34.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.3","Single Cell Type RNA - Fibroblasts [nTPM]":"20.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.5","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"4.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.2","Single Cell Type RNA - Hepatocytes [nTPM]":"13.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"34.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.5","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"13.0","Single Cell Type RNA - Langerhans cells [nTPM]":"8.7","Single Cell Type RNA - Late spermatids [nTPM]":"2.0","Single Cell Type RNA - Leydig cells [nTPM]":"20.2","Single Cell Type RNA - Macrophages [nTPM]":"7.6","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"106.8","Single Cell Type RNA - monocytes [nTPM]":"5.5","Single Cell Type RNA - Muller glia cells [nTPM]":"6.6","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"42.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"22.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.2","Single Cell Type RNA - Paneth cells [nTPM]":"4.1","Single Cell Type RNA - Peritubular cells [nTPM]":"15.8","Single Cell Type RNA - Plasma cells [nTPM]":"6.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"2.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.5","Single Cell Type RNA - T-cells [nTPM]":"4.3","Single Cell Type RNA - Theca cells [nTPM]":"3.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.3","Single Cell Type RNA - Urothelial cells [nTPM]":"8.8"},{"Gene":"ACVR1B","Gene synonym":["ActRIB","ACVRLK4","ALK4","SKR2"],"Ensembl":"ENSG00000135503","Gene description":"Activin A receptor type 1B","Uniprot":["P36896"],"Chromosome":"12","Position":"51951699-51997078","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"3.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB026126","HPA063761"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB026126":null,"HPA063761":"AB_2685115"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-2"},"Tissue RNA - adipose tissue [nTPM]":"16.5","Tissue RNA - adrenal gland [nTPM]":"10.3","Tissue RNA - amygdala [nTPM]":"20.7","Tissue RNA - appendix [nTPM]":"10.0","Tissue RNA - basal ganglia [nTPM]":"20.8","Tissue RNA - bone marrow [nTPM]":"13.5","Tissue RNA - breast [nTPM]":"13.2","Tissue RNA - cerebellum [nTPM]":"13.6","Tissue RNA - cerebral cortex [nTPM]":"23.4","Tissue RNA - cervix [nTPM]":"13.9","Tissue RNA - choroid plexus [nTPM]":"9.1","Tissue RNA - colon [nTPM]":"24.6","Tissue RNA - duodenum [nTPM]":"28.2","Tissue RNA - endometrium 1 [nTPM]":"8.8","Tissue RNA - epididymis [nTPM]":"18.0","Tissue RNA - esophagus [nTPM]":"20.9","Tissue RNA - fallopian tube [nTPM]":"15.3","Tissue RNA - gallbladder [nTPM]":"12.2","Tissue RNA - heart muscle [nTPM]":"10.1","Tissue RNA - hippocampal formation [nTPM]":"21.5","Tissue RNA - hypothalamus [nTPM]":"13.3","Tissue RNA - kidney [nTPM]":"34.3","Tissue RNA - liver [nTPM]":"29.9","Tissue RNA - lung [nTPM]":"14.7","Tissue RNA - lymph node [nTPM]":"6.4","Tissue RNA - medulla oblongata [nTPM]":"12.5","Tissue RNA - midbrain [nTPM]":"13.9","Tissue RNA - ovary [nTPM]":"9.4","Tissue RNA - pancreas [nTPM]":"40.7","Tissue RNA - parathyroid gland [nTPM]":"52.7","Tissue RNA - pituitary gland [nTPM]":"14.7","Tissue RNA - placenta [nTPM]":"11.1","Tissue RNA - pons [nTPM]":"13.1","Tissue RNA - prostate [nTPM]":"14.0","Tissue RNA - rectum [nTPM]":"24.4","Tissue RNA - retina [nTPM]":"17.4","Tissue RNA - salivary gland [nTPM]":"32.8","Tissue RNA - seminal vesicle [nTPM]":"15.3","Tissue RNA - skeletal muscle [nTPM]":"13.1","Tissue RNA - skin 1 [nTPM]":"45.6","Tissue RNA - small intestine [nTPM]":"26.1","Tissue RNA - smooth muscle [nTPM]":"8.1","Tissue RNA - spinal cord [nTPM]":"9.5","Tissue RNA - spleen [nTPM]":"8.8","Tissue RNA - stomach 1 [nTPM]":"24.9","Tissue RNA - testis [nTPM]":"15.7","Tissue RNA - thalamus [nTPM]":"16.1","Tissue RNA - thymus [nTPM]":"7.6","Tissue RNA - thyroid gland [nTPM]":"11.4","Tissue RNA - tongue [nTPM]":"8.8","Tissue RNA - tonsil [nTPM]":"7.4","Tissue RNA - urinary bladder [nTPM]":"12.6","Tissue RNA - vagina [nTPM]":"18.8","Tissue RNA - white matter [nTPM]":"18.3","Cell RNA - A-431 [nTPM]":"11.4","Cell RNA - A549 [nTPM]":"24.3","Cell RNA - AF22 [nTPM]":"18.6","Cell RNA - AN3-CA [nTPM]":"10.3","Cell RNA - ASC diff [nTPM]":"20.9","Cell RNA - ASC TERT1 [nTPM]":"16.2","Cell RNA - BEWO [nTPM]":"10.5","Cell RNA - BJ [nTPM]":"12.6","Cell RNA - BJ hTERT+ [nTPM]":"14.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.9","Cell RNA - CACO-2 [nTPM]":"49.5","Cell RNA - CAPAN-2 [nTPM]":"17.1","Cell RNA - Daudi [nTPM]":"5.0","Cell RNA - EFO-21 [nTPM]":"17.2","Cell RNA - fHDF\/TERT166 [nTPM]":"13.8","Cell RNA - GAMG [nTPM]":"14.6","Cell RNA - HaCaT [nTPM]":"19.6","Cell RNA - HAP1 [nTPM]":"17.8","Cell RNA - HBEC3-KT [nTPM]":"15.2","Cell RNA - HBF TERT88 [nTPM]":"13.5","Cell RNA - HDLM-2 [nTPM]":"7.3","Cell RNA - HEK 293 [nTPM]":"21.0","Cell RNA - HEL [nTPM]":"12.3","Cell RNA - HeLa [nTPM]":"5.9","Cell RNA - Hep G2 [nTPM]":"15.6","Cell RNA - HHSteC [nTPM]":"23.8","Cell RNA - HL-60 [nTPM]":"19.9","Cell RNA - HMC-1 [nTPM]":"43.8","Cell RNA - HSkMC [nTPM]":"32.0","Cell RNA - hTCEpi [nTPM]":"19.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.8","Cell RNA - hTERT-HME1 [nTPM]":"18.6","Cell RNA - hTERT-RPE1 [nTPM]":"13.9","Cell RNA - HUVEC TERT2 [nTPM]":"18.7","Cell RNA - JURKAT [nTPM]":"17.7","Cell RNA - K-562 [nTPM]":"13.3","Cell RNA - Karpas-707 [nTPM]":"14.9","Cell RNA - LHCN-M2 [nTPM]":"11.8","Cell RNA - MCF7 [nTPM]":"23.2","Cell RNA - MOLT-4 [nTPM]":"19.1","Cell RNA - NB-4 [nTPM]":"17.2","Cell RNA - NTERA-2 [nTPM]":"18.0","Cell RNA - OE19 [nTPM]":"24.0","Cell RNA - PC-3 [nTPM]":"8.5","Cell RNA - REH [nTPM]":"10.2","Cell RNA - RH-30 [nTPM]":"14.4","Cell RNA - RPMI-8226 [nTPM]":"6.4","Cell RNA - RPTEC TERT1 [nTPM]":"37.2","Cell RNA - RT4 [nTPM]":"17.0","Cell RNA - SCLC-21H [nTPM]":"23.5","Cell RNA - SH-SY5Y [nTPM]":"19.5","Cell RNA - SiHa [nTPM]":"13.6","Cell RNA - SK-BR-3 [nTPM]":"19.2","Cell RNA - SK-MEL-30 [nTPM]":"9.0","Cell RNA - SuSa [nTPM]":"13.1","Cell RNA - T-47d [nTPM]":"21.1","Cell RNA - THP-1 [nTPM]":"12.8","Cell RNA - TIME [nTPM]":"12.0","Cell RNA - U-138 MG [nTPM]":"9.0","Cell RNA - U-2 OS [nTPM]":"13.6","Cell RNA - U-2197 [nTPM]":"10.2","Cell RNA - U-251 MG [nTPM]":"6.1","Cell RNA - U-266\/70 [nTPM]":"9.0","Cell RNA - U-266\/84 [nTPM]":"6.8","Cell RNA - U-698 [nTPM]":"6.7","Cell RNA - U-87 MG [nTPM]":"9.7","Cell RNA - U-937 [nTPM]":"9.4","Cell RNA - WM-115 [nTPM]":"11.8","Blood RNA - basophil [nTPM]":"2.5","Blood RNA - classical monocyte [nTPM]":"1.2","Blood RNA - eosinophil [nTPM]":"3.9","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"1.8","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"2.2","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.5","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"20.7","Brain RNA - basal ganglia [nTPM]":"20.8","Brain RNA - cerebellum [nTPM]":"13.6","Brain RNA - cerebral cortex [nTPM]":"23.4","Brain RNA - hippocampal formation [nTPM]":"21.5","Brain RNA - hypothalamus [nTPM]":"13.3","Brain RNA - medulla oblongata [nTPM]":"12.5","Brain RNA - midbrain [nTPM]":"13.9","Brain RNA - pons [nTPM]":"13.1","Brain RNA - spinal cord [nTPM]":"9.5","Brain RNA - thalamus [nTPM]":"16.1","Brain RNA - white matter [nTPM]":"18.3","Single Cell Type RNA - Adipocytes [nTPM]":"8.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.4","Single Cell Type RNA - Astrocytes [nTPM]":"8.1","Single Cell Type RNA - B-cells [nTPM]":"2.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.3","Single Cell Type RNA - Bipolar cells [nTPM]":"45.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"12.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - dendritic cells [nTPM]":"2.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"49.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"17.7","Single Cell Type RNA - Early spermatids [nTPM]":"2.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.1","Single Cell Type RNA - Endothelial cells [nTPM]":"10.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"24.6","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"34.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.8","Single Cell Type RNA - Fibroblasts [nTPM]":"12.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.0","Single Cell Type RNA - granulocytes [nTPM]":"11.4","Single Cell Type RNA - Granulosa cells [nTPM]":"9.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.9","Single Cell Type RNA - Hepatocytes [nTPM]":"24.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.0","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"30.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.7","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"16.7","Single Cell Type RNA - Langerhans cells [nTPM]":"5.3","Single Cell Type RNA - Late spermatids [nTPM]":"8.4","Single Cell Type RNA - Leydig cells [nTPM]":"9.9","Single Cell Type RNA - Macrophages [nTPM]":"10.0","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"10.1","Single Cell Type RNA - Muller glia cells [nTPM]":"8.8","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.3","Single Cell Type RNA - Paneth cells [nTPM]":"22.1","Single Cell Type RNA - Peritubular cells [nTPM]":"9.4","Single Cell Type RNA - Plasma cells [nTPM]":"2.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"31.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.2","Single Cell Type RNA - Spermatocytes [nTPM]":"3.8","Single Cell Type RNA - Spermatogonia [nTPM]":"16.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"25.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"4.6","Single Cell Type RNA - Theca cells [nTPM]":"5.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.7","Single Cell Type RNA - Urothelial cells [nTPM]":"15.5"},{"Gene":"ACVR2B","Gene synonym":["ActR-IIB"],"Ensembl":"ENSG00000114739","Gene description":"Activin A receptor type 2B","Uniprot":["Q13705"],"Chromosome":"3","Position":"38453890-38493142","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Heterotaxy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"5.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"20.9","NTERA-2":"25.9","SuSa":"14.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025115","HPA040384"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025115":null,"HPA040384":"AB_2732484"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.1","Tissue RNA - adrenal gland [nTPM]":"2.8","Tissue RNA - amygdala [nTPM]":"3.2","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"3.2","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"1.7","Tissue RNA - cerebellum [nTPM]":"5.2","Tissue RNA - cerebral cortex [nTPM]":"2.8","Tissue RNA - cervix [nTPM]":"1.9","Tissue RNA - choroid plexus [nTPM]":"1.0","Tissue RNA - colon [nTPM]":"1.5","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"1.7","Tissue RNA - epididymis [nTPM]":"1.7","Tissue RNA - esophagus [nTPM]":"0.7","Tissue RNA - fallopian tube [nTPM]":"1.9","Tissue RNA - gallbladder [nTPM]":"0.6","Tissue RNA - heart muscle [nTPM]":"1.4","Tissue RNA - hippocampal formation [nTPM]":"2.6","Tissue RNA - hypothalamus [nTPM]":"3.0","Tissue RNA - kidney [nTPM]":"1.8","Tissue RNA - liver [nTPM]":"2.2","Tissue RNA - lung [nTPM]":"1.3","Tissue RNA - lymph node [nTPM]":"0.7","Tissue RNA - medulla oblongata [nTPM]":"2.6","Tissue RNA - midbrain [nTPM]":"3.2","Tissue RNA - ovary [nTPM]":"2.9","Tissue RNA - pancreas [nTPM]":"2.5","Tissue RNA - parathyroid gland [nTPM]":"3.3","Tissue RNA - pituitary gland [nTPM]":"2.0","Tissue RNA - placenta [nTPM]":"2.5","Tissue RNA - pons [nTPM]":"2.6","Tissue RNA - prostate [nTPM]":"1.3","Tissue RNA - rectum [nTPM]":"1.1","Tissue RNA - retina [nTPM]":"6.5","Tissue RNA - salivary gland [nTPM]":"1.7","Tissue RNA - seminal vesicle [nTPM]":"1.3","Tissue RNA - skeletal muscle [nTPM]":"6.0","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"1.1","Tissue RNA - smooth muscle [nTPM]":"0.9","Tissue RNA - spinal cord [nTPM]":"2.3","Tissue RNA - spleen [nTPM]":"1.0","Tissue RNA - stomach 1 [nTPM]":"1.5","Tissue RNA - testis [nTPM]":"2.5","Tissue RNA - thalamus [nTPM]":"2.9","Tissue RNA - thymus [nTPM]":"4.1","Tissue RNA - thyroid gland [nTPM]":"1.6","Tissue RNA - tongue [nTPM]":"2.8","Tissue RNA - tonsil [nTPM]":"0.6","Tissue RNA - urinary bladder [nTPM]":"1.4","Tissue RNA - vagina [nTPM]":"1.4","Tissue RNA - white matter [nTPM]":"3.6","Cell RNA - A-431 [nTPM]":"1.1","Cell RNA - A549 [nTPM]":"1.8","Cell RNA - AF22 [nTPM]":"20.9","Cell RNA - AN3-CA [nTPM]":"1.8","Cell RNA - ASC diff [nTPM]":"0.8","Cell RNA - ASC TERT1 [nTPM]":"0.5","Cell RNA - BEWO [nTPM]":"11.2","Cell RNA - BJ [nTPM]":"0.4","Cell RNA - BJ hTERT+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.9","Cell RNA - CACO-2 [nTPM]":"3.1","Cell RNA - CAPAN-2 [nTPM]":"1.4","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"1.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.5","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"1.3","Cell RNA - HAP1 [nTPM]":"8.1","Cell RNA - HBEC3-KT [nTPM]":"1.3","Cell RNA - HBF TERT88 [nTPM]":"1.1","Cell RNA - HDLM-2 [nTPM]":"3.2","Cell RNA - HEK 293 [nTPM]":"5.2","Cell RNA - HEL [nTPM]":"5.6","Cell RNA - HeLa [nTPM]":"3.5","Cell RNA - Hep G2 [nTPM]":"4.6","Cell RNA - HHSteC [nTPM]":"1.0","Cell RNA - HL-60 [nTPM]":"4.0","Cell RNA - HMC-1 [nTPM]":"2.0","Cell RNA - HSkMC [nTPM]":"0.8","Cell RNA - hTCEpi [nTPM]":"1.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.6","Cell RNA - hTERT-HME1 [nTPM]":"2.3","Cell RNA - hTERT-RPE1 [nTPM]":"1.3","Cell RNA - HUVEC TERT2 [nTPM]":"1.4","Cell RNA - JURKAT [nTPM]":"8.0","Cell RNA - K-562 [nTPM]":"9.4","Cell RNA - Karpas-707 [nTPM]":"1.8","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"1.7","Cell RNA - MOLT-4 [nTPM]":"6.9","Cell RNA - NB-4 [nTPM]":"2.5","Cell RNA - NTERA-2 [nTPM]":"25.9","Cell RNA - OE19 [nTPM]":"1.1","Cell RNA - PC-3 [nTPM]":"0.9","Cell RNA - REH [nTPM]":"2.2","Cell RNA - RH-30 [nTPM]":"7.0","Cell RNA - RPMI-8226 [nTPM]":"1.4","Cell RNA - RPTEC TERT1 [nTPM]":"1.3","Cell RNA - RT4 [nTPM]":"2.6","Cell RNA - SCLC-21H [nTPM]":"4.9","Cell RNA - SH-SY5Y [nTPM]":"8.5","Cell RNA - SiHa [nTPM]":"0.6","Cell RNA - SK-BR-3 [nTPM]":"3.2","Cell RNA - SK-MEL-30 [nTPM]":"3.0","Cell RNA - SuSa [nTPM]":"14.7","Cell RNA - T-47d [nTPM]":"1.7","Cell RNA - THP-1 [nTPM]":"5.2","Cell RNA - TIME [nTPM]":"1.2","Cell RNA - U-138 MG [nTPM]":"0.7","Cell RNA - U-2 OS [nTPM]":"3.3","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"1.8","Cell RNA - U-266\/70 [nTPM]":"5.0","Cell RNA - U-266\/84 [nTPM]":"7.3","Cell RNA - U-698 [nTPM]":"1.2","Cell RNA - U-87 MG [nTPM]":"0.7","Cell RNA - U-937 [nTPM]":"3.2","Cell RNA - WM-115 [nTPM]":"1.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.2","Brain RNA - basal ganglia [nTPM]":"3.2","Brain RNA - cerebellum [nTPM]":"5.2","Brain RNA - cerebral cortex [nTPM]":"2.8","Brain RNA - hippocampal formation [nTPM]":"2.6","Brain RNA - hypothalamus [nTPM]":"3.0","Brain RNA - medulla oblongata [nTPM]":"2.6","Brain RNA - midbrain [nTPM]":"3.2","Brain RNA - pons [nTPM]":"2.6","Brain RNA - spinal cord [nTPM]":"2.3","Brain RNA - thalamus [nTPM]":"2.9","Brain RNA - white matter [nTPM]":"3.6","Single Cell Type RNA - Adipocytes [nTPM]":"7.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.1","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"23.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"3.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.5","Single Cell Type RNA - dendritic cells [nTPM]":"1.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.6","Single Cell Type RNA - Early spermatids [nTPM]":"11.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.0","Single Cell Type RNA - Endothelial cells [nTPM]":"7.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.6","Single Cell Type RNA - Fibroblasts [nTPM]":"3.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.3","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"17.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"8.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.6","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.2","Single Cell Type RNA - Langerhans cells [nTPM]":"6.4","Single Cell Type RNA - Late spermatids [nTPM]":"15.8","Single Cell Type RNA - Leydig cells [nTPM]":"11.8","Single Cell Type RNA - Macrophages [nTPM]":"2.4","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"7.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.2","Single Cell Type RNA - Paneth cells [nTPM]":"5.3","Single Cell Type RNA - Peritubular cells [nTPM]":"7.9","Single Cell Type RNA - Plasma cells [nTPM]":"1.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"25.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.7","Single Cell Type RNA - Spermatocytes [nTPM]":"11.4","Single Cell Type RNA - Spermatogonia [nTPM]":"17.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.2","Single Cell Type RNA - T-cells [nTPM]":"2.6","Single Cell Type RNA - Theca cells [nTPM]":"7.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.4","Single Cell Type RNA - Urothelial cells [nTPM]":"3.9"},{"Gene":"ACVRL1","Gene synonym":["ACVRLK1","ALK1","HHT","HHT2","ORW2"],"Ensembl":"ENSG00000139567","Gene description":"Activin A receptor like type 1","Uniprot":["P37023"],"Chromosome":"12","Position":"51906908-51923361","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Angiogenesis"],"Molecular function":["Kinase","Receptor","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"96.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"107.3","Distal enterocytes":"182.7","Endothelial cells":"84.7","Fibroblasts":"56.0","Hepatic stellate cells":"60.3","Paneth cells":"74.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"19","RNA blood cell specific nTPM":{"classical monocyte":"1.5","myeloid DC":"2.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"dendritic cells":"2.1","monocytes":"1.5"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"61.4","ASC TERT1":"42.1","EFO-21":"61.0","HUVEC TERT2":"200.0","TIME":"161.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007041"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA007041":"AB_1078097"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.98e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Tissue RNA - adipose tissue [nTPM]":"49.2","Tissue RNA - adrenal gland [nTPM]":"12.1","Tissue RNA - amygdala [nTPM]":"17.1","Tissue RNA - appendix [nTPM]":"20.1","Tissue RNA - basal ganglia [nTPM]":"14.5","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"38.4","Tissue RNA - cerebellum [nTPM]":"15.5","Tissue RNA - cerebral cortex [nTPM]":"14.9","Tissue RNA - cervix [nTPM]":"35.9","Tissue RNA - choroid plexus [nTPM]":"10.5","Tissue RNA - colon [nTPM]":"39.2","Tissue RNA - duodenum [nTPM]":"10.2","Tissue RNA - endometrium 1 [nTPM]":"28.1","Tissue RNA - epididymis [nTPM]":"4.3","Tissue RNA - esophagus [nTPM]":"11.4","Tissue RNA - fallopian tube [nTPM]":"32.7","Tissue RNA - gallbladder [nTPM]":"14.3","Tissue RNA - heart muscle [nTPM]":"38.5","Tissue RNA - hippocampal formation [nTPM]":"13.3","Tissue RNA - hypothalamus [nTPM]":"14.6","Tissue RNA - kidney [nTPM]":"29.8","Tissue RNA - liver [nTPM]":"3.3","Tissue RNA - lung [nTPM]":"96.3","Tissue RNA - lymph node [nTPM]":"15.1","Tissue RNA - medulla oblongata [nTPM]":"17.8","Tissue RNA - midbrain [nTPM]":"16.7","Tissue RNA - ovary [nTPM]":"4.8","Tissue RNA - pancreas [nTPM]":"12.0","Tissue RNA - parathyroid gland [nTPM]":"23.6","Tissue RNA - pituitary gland [nTPM]":"6.2","Tissue RNA - placenta [nTPM]":"83.8","Tissue RNA - pons [nTPM]":"18.7","Tissue RNA - prostate [nTPM]":"17.7","Tissue RNA - rectum [nTPM]":"28.4","Tissue RNA - retina [nTPM]":"0.7","Tissue RNA - salivary gland [nTPM]":"11.8","Tissue RNA - seminal vesicle [nTPM]":"13.3","Tissue RNA - skeletal muscle [nTPM]":"18.2","Tissue RNA - skin 1 [nTPM]":"18.5","Tissue RNA - small intestine [nTPM]":"28.5","Tissue RNA - smooth muscle [nTPM]":"16.2","Tissue RNA - spinal cord [nTPM]":"14.0","Tissue RNA - spleen [nTPM]":"29.2","Tissue RNA - stomach 1 [nTPM]":"19.1","Tissue RNA - testis [nTPM]":"1.7","Tissue RNA - thalamus [nTPM]":"22.0","Tissue RNA - thymus [nTPM]":"4.6","Tissue RNA - thyroid gland [nTPM]":"29.2","Tissue RNA - tongue [nTPM]":"15.7","Tissue RNA - tonsil [nTPM]":"6.1","Tissue RNA - urinary bladder [nTPM]":"25.1","Tissue RNA - vagina [nTPM]":"25.6","Tissue RNA - white matter [nTPM]":"15.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.7","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"61.4","Cell RNA - ASC TERT1 [nTPM]":"42.1","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"3.0","Cell RNA - BJ hTERT+ [nTPM]":"5.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"61.0","Cell RNA - fHDF\/TERT166 [nTPM]":"24.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"2.1","Cell RNA - HEL [nTPM]":"1.4","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"9.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.3","Cell RNA - HSkMC [nTPM]":"16.8","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.4","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"200.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"1.1","Cell RNA - MCF7 [nTPM]":"0.5","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.9","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"4.1","Cell RNA - TIME [nTPM]":"161.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.7","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.9","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.5","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"2.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"17.1","Brain RNA - basal ganglia [nTPM]":"14.5","Brain RNA - cerebellum [nTPM]":"15.5","Brain RNA - cerebral cortex [nTPM]":"14.9","Brain RNA - hippocampal formation [nTPM]":"13.3","Brain RNA - hypothalamus [nTPM]":"14.6","Brain RNA - medulla oblongata [nTPM]":"17.8","Brain RNA - midbrain [nTPM]":"16.7","Brain RNA - pons [nTPM]":"18.7","Brain RNA - spinal cord [nTPM]":"14.0","Brain RNA - thalamus [nTPM]":"22.0","Brain RNA - white matter [nTPM]":"15.0","Single Cell Type RNA - Adipocytes [nTPM]":"107.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"182.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"4.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.9","Single Cell Type RNA - Endothelial cells [nTPM]":"84.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"36.9","Single Cell Type RNA - Fibroblasts [nTPM]":"56.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"60.3","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"30.9","Single Cell Type RNA - Langerhans cells [nTPM]":"12.4","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"11.8","Single Cell Type RNA - Macrophages [nTPM]":"7.8","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"25.3","Single Cell Type RNA - monocytes [nTPM]":"9.9","Single Cell Type RNA - Muller glia cells [nTPM]":"2.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"74.7","Single Cell Type RNA - Peritubular cells [nTPM]":"3.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"32.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.6","Single Cell Type RNA - T-cells [nTPM]":"1.2","Single Cell Type RNA - Theca cells [nTPM]":"0.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"49.3","Single Cell Type RNA - Urothelial cells [nTPM]":"1.0"},{"Gene":"ACY1","Gene synonym":[],"Ensembl":"ENSG00000243989","Gene description":"Aminoacylase 1","Uniprot":["Q03154"],"Chromosome":"3","Position":"51983340-51989197","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"intestine":"181.5","kidney":"449.9","liver":"274.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"31.6","Gastric mucus-secreting cells":"32.6","Proximal enterocytes":"144.8","Proximal tubular cells":"92.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"128.0"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003695","HPA036174","HPA036175"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"23000000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB003695":"AB_425286","HPA036174":"AB_2674988","HPA036175":"AB_2674989"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.93e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.77e-4"},"Tissue RNA - adipose tissue [nTPM]":"19.2","Tissue RNA - adrenal gland [nTPM]":"24.0","Tissue RNA - amygdala [nTPM]":"5.6","Tissue RNA - appendix [nTPM]":"7.3","Tissue RNA - basal ganglia [nTPM]":"5.7","Tissue RNA - bone marrow [nTPM]":"8.8","Tissue RNA - breast [nTPM]":"20.7","Tissue RNA - cerebellum [nTPM]":"6.4","Tissue RNA - cerebral cortex [nTPM]":"7.3","Tissue RNA - cervix [nTPM]":"13.9","Tissue RNA - choroid plexus [nTPM]":"11.6","Tissue RNA - colon [nTPM]":"30.6","Tissue RNA - duodenum [nTPM]":"181.5","Tissue RNA - endometrium 1 [nTPM]":"4.3","Tissue RNA - epididymis [nTPM]":"21.8","Tissue RNA - esophagus [nTPM]":"10.7","Tissue RNA - fallopian tube [nTPM]":"13.0","Tissue RNA - gallbladder [nTPM]":"10.7","Tissue RNA - heart muscle [nTPM]":"14.5","Tissue RNA - hippocampal formation [nTPM]":"5.1","Tissue RNA - hypothalamus [nTPM]":"6.0","Tissue RNA - kidney [nTPM]":"449.9","Tissue RNA - liver [nTPM]":"274.9","Tissue RNA - lung [nTPM]":"9.2","Tissue RNA - lymph node [nTPM]":"7.2","Tissue RNA - medulla oblongata [nTPM]":"6.5","Tissue RNA - midbrain [nTPM]":"5.9","Tissue RNA - ovary [nTPM]":"4.8","Tissue RNA - pancreas [nTPM]":"8.7","Tissue RNA - parathyroid gland [nTPM]":"28.2","Tissue RNA - pituitary gland [nTPM]":"4.7","Tissue RNA - placenta [nTPM]":"9.7","Tissue RNA - pons [nTPM]":"6.6","Tissue RNA - prostate [nTPM]":"14.3","Tissue RNA - rectum [nTPM]":"30.5","Tissue RNA - retina [nTPM]":"1.9","Tissue RNA - salivary gland [nTPM]":"16.4","Tissue RNA - seminal vesicle [nTPM]":"11.1","Tissue RNA - skeletal muscle [nTPM]":"20.2","Tissue RNA - skin 1 [nTPM]":"8.2","Tissue RNA - small intestine [nTPM]":"138.2","Tissue RNA - smooth muscle [nTPM]":"6.9","Tissue RNA - spinal cord [nTPM]":"6.7","Tissue RNA - spleen [nTPM]":"8.1","Tissue RNA - stomach 1 [nTPM]":"23.6","Tissue RNA - testis [nTPM]":"3.2","Tissue RNA - thalamus [nTPM]":"6.1","Tissue RNA - thymus [nTPM]":"5.1","Tissue RNA - thyroid gland [nTPM]":"21.0","Tissue RNA - tongue [nTPM]":"34.6","Tissue RNA - tonsil [nTPM]":"9.2","Tissue RNA - urinary bladder [nTPM]":"12.5","Tissue RNA - vagina [nTPM]":"7.1","Tissue RNA - white matter [nTPM]":"6.6","Cell RNA - A-431 [nTPM]":"15.9","Cell RNA - A549 [nTPM]":"26.2","Cell RNA - AF22 [nTPM]":"13.2","Cell RNA - AN3-CA [nTPM]":"34.1","Cell RNA - ASC diff [nTPM]":"28.9","Cell RNA - ASC TERT1 [nTPM]":"39.4","Cell RNA - BEWO [nTPM]":"40.5","Cell RNA - BJ [nTPM]":"12.6","Cell RNA - BJ hTERT+ [nTPM]":"28.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"29.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.9","Cell RNA - CACO-2 [nTPM]":"41.2","Cell RNA - CAPAN-2 [nTPM]":"67.9","Cell RNA - Daudi [nTPM]":"7.2","Cell RNA - EFO-21 [nTPM]":"12.2","Cell RNA - fHDF\/TERT166 [nTPM]":"22.0","Cell RNA - GAMG [nTPM]":"13.2","Cell RNA - HaCaT [nTPM]":"20.0","Cell RNA - HAP1 [nTPM]":"14.7","Cell RNA - HBEC3-KT [nTPM]":"81.2","Cell RNA - HBF TERT88 [nTPM]":"11.5","Cell RNA - HDLM-2 [nTPM]":"21.8","Cell RNA - HEK 293 [nTPM]":"10.7","Cell RNA - HEL [nTPM]":"25.3","Cell RNA - HeLa [nTPM]":"13.9","Cell RNA - Hep G2 [nTPM]":"128.0","Cell RNA - HHSteC [nTPM]":"49.7","Cell RNA - HL-60 [nTPM]":"19.8","Cell RNA - HMC-1 [nTPM]":"21.0","Cell RNA - HSkMC [nTPM]":"48.0","Cell RNA - hTCEpi [nTPM]":"67.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.4","Cell RNA - hTERT-HME1 [nTPM]":"69.1","Cell RNA - hTERT-RPE1 [nTPM]":"25.8","Cell RNA - HUVEC TERT2 [nTPM]":"11.5","Cell RNA - JURKAT [nTPM]":"14.6","Cell RNA - K-562 [nTPM]":"47.1","Cell RNA - Karpas-707 [nTPM]":"23.9","Cell RNA - LHCN-M2 [nTPM]":"29.9","Cell RNA - MCF7 [nTPM]":"35.2","Cell RNA - MOLT-4 [nTPM]":"0.6","Cell RNA - NB-4 [nTPM]":"38.9","Cell RNA - NTERA-2 [nTPM]":"23.4","Cell RNA - OE19 [nTPM]":"92.1","Cell RNA - PC-3 [nTPM]":"39.3","Cell RNA - REH [nTPM]":"8.0","Cell RNA - RH-30 [nTPM]":"14.1","Cell RNA - RPMI-8226 [nTPM]":"63.5","Cell RNA - RPTEC TERT1 [nTPM]":"74.5","Cell RNA - RT4 [nTPM]":"50.8","Cell RNA - SCLC-21H [nTPM]":"16.9","Cell RNA - SH-SY5Y [nTPM]":"18.2","Cell RNA - SiHa [nTPM]":"12.6","Cell RNA - SK-BR-3 [nTPM]":"62.6","Cell RNA - SK-MEL-30 [nTPM]":"29.5","Cell RNA - SuSa [nTPM]":"7.5","Cell RNA - T-47d [nTPM]":"42.3","Cell RNA - THP-1 [nTPM]":"27.9","Cell RNA - TIME [nTPM]":"7.1","Cell RNA - U-138 MG [nTPM]":"22.0","Cell RNA - U-2 OS [nTPM]":"21.9","Cell RNA - U-2197 [nTPM]":"24.8","Cell RNA - U-251 MG [nTPM]":"18.8","Cell RNA - U-266\/70 [nTPM]":"61.7","Cell RNA - U-266\/84 [nTPM]":"16.9","Cell RNA - U-698 [nTPM]":"12.1","Cell RNA - U-87 MG [nTPM]":"28.1","Cell RNA - U-937 [nTPM]":"42.9","Cell RNA - WM-115 [nTPM]":"29.0","Blood RNA - basophil [nTPM]":"9.1","Blood RNA - classical monocyte [nTPM]":"15.7","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"10.7","Blood RNA - intermediate monocyte [nTPM]":"15.1","Blood RNA - MAIT T-cell [nTPM]":"5.7","Blood RNA - memory B-cell [nTPM]":"7.4","Blood RNA - memory CD4 T-cell [nTPM]":"2.6","Blood RNA - memory CD8 T-cell [nTPM]":"4.5","Blood RNA - myeloid DC [nTPM]":"21.2","Blood RNA - naive B-cell [nTPM]":"6.1","Blood RNA - naive CD4 T-cell [nTPM]":"4.1","Blood RNA - naive CD8 T-cell [nTPM]":"4.7","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"20.4","Blood RNA - non-classical monocyte [nTPM]":"6.4","Blood RNA - plasmacytoid DC [nTPM]":"2.8","Blood RNA - T-reg [nTPM]":"3.8","Blood RNA - total PBMC [nTPM]":"9.7","Brain RNA - amygdala [nTPM]":"5.6","Brain RNA - basal ganglia [nTPM]":"5.7","Brain RNA - cerebellum [nTPM]":"6.4","Brain RNA - cerebral cortex [nTPM]":"7.3","Brain RNA - hippocampal formation [nTPM]":"5.1","Brain RNA - hypothalamus [nTPM]":"6.0","Brain RNA - medulla oblongata [nTPM]":"6.5","Brain RNA - midbrain [nTPM]":"5.9","Brain RNA - pons [nTPM]":"6.6","Brain RNA - spinal cord [nTPM]":"6.7","Brain RNA - thalamus [nTPM]":"6.1","Brain RNA - white matter [nTPM]":"6.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"4.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"2.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.9","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"31.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"16.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.9","Single Cell Type RNA - Endothelial cells [nTPM]":"0.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"15.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.5","Single Cell Type RNA - Fibroblasts [nTPM]":"4.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.6","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"13.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.2","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"4.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"9.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.4","Single Cell Type RNA - Paneth cells [nTPM]":"23.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"14.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"144.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"92.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.1","Single Cell Type RNA - T-cells [nTPM]":"2.6","Single Cell Type RNA - Theca cells [nTPM]":"1.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"ADA2","Gene synonym":["ADGF","CECR1","IDGFL"],"Ensembl":"ENSG00000093072","Gene description":"Adenosine deaminase 2","Uniprot":["Q9NZK5"],"Chromosome":"22","Position":"17178790-17258235","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Heparin-binding","Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"106.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"27.6","Glandular and luminal cells":"22.0","Hofbauer cells":"57.6","Macrophages":"62.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"23.7","EFO-21":"21.4","HUVEC TERT2":"24.0","Karpas-707":"44.9","MOLT-4":"38.9","U-266\/70":"23.8","U-937":"39.6"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007888"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"58000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA007888":"AB_1078495"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.26e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.91e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Tissue RNA - adipose tissue [nTPM]":"14.0","Tissue RNA - adrenal gland [nTPM]":"11.3","Tissue RNA - amygdala [nTPM]":"8.3","Tissue RNA - appendix [nTPM]":"39.4","Tissue RNA - basal ganglia [nTPM]":"9.9","Tissue RNA - bone marrow [nTPM]":"22.8","Tissue RNA - breast [nTPM]":"17.6","Tissue RNA - cerebellum [nTPM]":"10.6","Tissue RNA - cerebral cortex [nTPM]":"7.9","Tissue RNA - cervix [nTPM]":"22.0","Tissue RNA - choroid plexus [nTPM]":"20.5","Tissue RNA - colon [nTPM]":"28.3","Tissue RNA - duodenum [nTPM]":"18.1","Tissue RNA - endometrium 1 [nTPM]":"19.9","Tissue RNA - epididymis [nTPM]":"2.7","Tissue RNA - esophagus [nTPM]":"12.0","Tissue RNA - fallopian tube [nTPM]":"51.5","Tissue RNA - gallbladder [nTPM]":"32.1","Tissue RNA - heart muscle [nTPM]":"39.6","Tissue RNA - hippocampal formation [nTPM]":"7.8","Tissue RNA - hypothalamus [nTPM]":"10.9","Tissue RNA - kidney [nTPM]":"14.5","Tissue RNA - liver [nTPM]":"21.1","Tissue RNA - lung [nTPM]":"54.9","Tissue RNA - lymph node [nTPM]":"47.3","Tissue RNA - medulla oblongata [nTPM]":"16.3","Tissue RNA - midbrain [nTPM]":"11.4","Tissue RNA - ovary [nTPM]":"12.1","Tissue RNA - pancreas [nTPM]":"13.9","Tissue RNA - parathyroid gland [nTPM]":"5.4","Tissue RNA - pituitary gland [nTPM]":"22.5","Tissue RNA - placenta [nTPM]":"15.2","Tissue RNA - pons [nTPM]":"14.7","Tissue RNA - prostate [nTPM]":"15.4","Tissue RNA - rectum [nTPM]":"34.3","Tissue RNA - retina [nTPM]":"11.0","Tissue RNA - salivary gland [nTPM]":"15.6","Tissue RNA - seminal vesicle [nTPM]":"17.1","Tissue RNA - skeletal muscle [nTPM]":"3.4","Tissue RNA - skin 1 [nTPM]":"4.7","Tissue RNA - small intestine [nTPM]":"26.1","Tissue RNA - smooth muscle [nTPM]":"23.4","Tissue RNA - spinal cord [nTPM]":"13.7","Tissue RNA - spleen [nTPM]":"106.3","Tissue RNA - stomach 1 [nTPM]":"19.6","Tissue RNA - testis [nTPM]":"18.4","Tissue RNA - thalamus [nTPM]":"12.9","Tissue RNA - thymus [nTPM]":"53.7","Tissue RNA - thyroid gland [nTPM]":"16.9","Tissue RNA - tongue [nTPM]":"4.3","Tissue RNA - tonsil [nTPM]":"60.7","Tissue RNA - urinary bladder [nTPM]":"34.7","Tissue RNA - vagina [nTPM]":"6.5","Tissue RNA - white matter [nTPM]":"21.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"6.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.8","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"2.3","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"23.7","Cell RNA - Daudi [nTPM]":"6.0","Cell RNA - EFO-21 [nTPM]":"21.4","Cell RNA - fHDF\/TERT166 [nTPM]":"7.2","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"1.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"4.0","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"11.3","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"24.0","Cell RNA - JURKAT [nTPM]":"9.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"44.9","Cell RNA - LHCN-M2 [nTPM]":"0.9","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"38.9","Cell RNA - NB-4 [nTPM]":"1.1","Cell RNA - NTERA-2 [nTPM]":"17.8","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"1.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"6.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"9.3","Cell RNA - SCLC-21H [nTPM]":"10.9","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"19.1","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"9.7","Cell RNA - TIME [nTPM]":"3.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"23.8","Cell RNA - U-266\/84 [nTPM]":"2.3","Cell RNA - U-698 [nTPM]":"1.7","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"39.6","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"17.5","Blood RNA - classical monocyte [nTPM]":"212.9","Blood RNA - eosinophil [nTPM]":"11.3","Blood RNA - gdT-cell [nTPM]":"34.6","Blood RNA - intermediate monocyte [nTPM]":"204.9","Blood RNA - MAIT T-cell [nTPM]":"26.8","Blood RNA - memory B-cell [nTPM]":"25.8","Blood RNA - memory CD4 T-cell [nTPM]":"27.4","Blood RNA - memory CD8 T-cell [nTPM]":"34.1","Blood RNA - myeloid DC [nTPM]":"139.1","Blood RNA - naive B-cell [nTPM]":"19.7","Blood RNA - naive CD4 T-cell [nTPM]":"31.6","Blood RNA - naive CD8 T-cell [nTPM]":"32.4","Blood RNA - neutrophil [nTPM]":"10.5","Blood RNA - NK-cell [nTPM]":"44.9","Blood RNA - non-classical monocyte [nTPM]":"176.1","Blood RNA - plasmacytoid DC [nTPM]":"57.4","Blood RNA - T-reg [nTPM]":"17.2","Blood RNA - total PBMC [nTPM]":"170.7","Brain RNA - amygdala [nTPM]":"8.3","Brain RNA - basal ganglia [nTPM]":"9.9","Brain RNA - cerebellum [nTPM]":"10.6","Brain RNA - cerebral cortex [nTPM]":"7.9","Brain RNA - hippocampal formation [nTPM]":"7.8","Brain RNA - hypothalamus [nTPM]":"10.9","Brain RNA - medulla oblongata [nTPM]":"16.3","Brain RNA - midbrain [nTPM]":"11.4","Brain RNA - pons [nTPM]":"14.7","Brain RNA - spinal cord [nTPM]":"13.7","Brain RNA - thalamus [nTPM]":"12.9","Brain RNA - white matter [nTPM]":"21.1","Single Cell Type RNA - Adipocytes [nTPM]":"8.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"7.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"11.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"13.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.6","Single Cell Type RNA - Endothelial cells [nTPM]":"2.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.9","Single Cell Type RNA - Fibroblasts [nTPM]":"2.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"22.0","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"12.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"57.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"62.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"12.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"8.2","Single Cell Type RNA - Theca cells [nTPM]":"3.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"ADAM10","Gene synonym":["CD156C","HsT18717","kuz","MADM"],"Ensembl":"ENSG00000137845","Gene description":"ADAM metallopeptidase domain 10","Uniprot":["O14672"],"Chromosome":"15","Position":"58588809-58749791","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Notch signaling pathway"],"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Alzheimer disease","Amyloidosis","Cancer-related genes","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"377.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-2197":"296.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB001709","HPA050670"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"690000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB001709":null,"HPA050670":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.46e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.90e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Tissue RNA - adipose tissue [nTPM]":"14.9","Tissue RNA - adrenal gland [nTPM]":"8.7","Tissue RNA - amygdala [nTPM]":"11.4","Tissue RNA - appendix [nTPM]":"19.0","Tissue RNA - basal ganglia [nTPM]":"18.6","Tissue RNA - bone marrow [nTPM]":"18.7","Tissue RNA - breast [nTPM]":"15.2","Tissue RNA - cerebellum [nTPM]":"20.2","Tissue RNA - cerebral cortex [nTPM]":"15.0","Tissue RNA - cervix [nTPM]":"16.0","Tissue RNA - choroid plexus [nTPM]":"9.7","Tissue RNA - colon [nTPM]":"22.2","Tissue RNA - duodenum [nTPM]":"15.9","Tissue RNA - endometrium 1 [nTPM]":"16.3","Tissue RNA - epididymis [nTPM]":"7.7","Tissue RNA - esophagus [nTPM]":"15.4","Tissue RNA - fallopian tube [nTPM]":"13.9","Tissue RNA - gallbladder [nTPM]":"18.9","Tissue RNA - heart muscle [nTPM]":"12.1","Tissue RNA - hippocampal formation [nTPM]":"12.2","Tissue RNA - hypothalamus [nTPM]":"12.7","Tissue RNA - kidney [nTPM]":"18.0","Tissue RNA - liver [nTPM]":"16.1","Tissue RNA - lung [nTPM]":"21.0","Tissue RNA - lymph node [nTPM]":"22.2","Tissue RNA - medulla oblongata [nTPM]":"18.2","Tissue RNA - midbrain [nTPM]":"17.6","Tissue RNA - ovary [nTPM]":"14.1","Tissue RNA - pancreas [nTPM]":"8.8","Tissue RNA - parathyroid gland [nTPM]":"7.9","Tissue RNA - pituitary gland [nTPM]":"8.2","Tissue RNA - placenta [nTPM]":"29.0","Tissue RNA - pons [nTPM]":"17.5","Tissue RNA - prostate [nTPM]":"25.2","Tissue RNA - rectum [nTPM]":"17.2","Tissue RNA - retina [nTPM]":"10.8","Tissue RNA - salivary gland [nTPM]":"9.3","Tissue RNA - seminal vesicle [nTPM]":"12.2","Tissue RNA - skeletal muscle [nTPM]":"6.1","Tissue RNA - skin 1 [nTPM]":"16.9","Tissue RNA - small intestine [nTPM]":"17.5","Tissue RNA - smooth muscle [nTPM]":"13.3","Tissue RNA - spinal cord [nTPM]":"13.7","Tissue RNA - spleen [nTPM]":"29.0","Tissue RNA - stomach 1 [nTPM]":"20.3","Tissue RNA - testis [nTPM]":"8.5","Tissue RNA - thalamus [nTPM]":"15.5","Tissue RNA - thymus [nTPM]":"42.7","Tissue RNA - thyroid gland [nTPM]":"28.6","Tissue RNA - tongue [nTPM]":"7.1","Tissue RNA - tonsil [nTPM]":"16.4","Tissue RNA - urinary bladder [nTPM]":"28.0","Tissue RNA - vagina [nTPM]":"10.4","Tissue RNA - white matter [nTPM]":"25.2","Cell RNA - A-431 [nTPM]":"48.4","Cell RNA - A549 [nTPM]":"88.5","Cell RNA - AF22 [nTPM]":"27.6","Cell RNA - AN3-CA [nTPM]":"31.2","Cell RNA - ASC diff [nTPM]":"34.8","Cell RNA - ASC TERT1 [nTPM]":"49.8","Cell RNA - BEWO [nTPM]":"70.0","Cell RNA - BJ [nTPM]":"39.0","Cell RNA - BJ hTERT+ [nTPM]":"116.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"28.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"39.1","Cell RNA - CACO-2 [nTPM]":"39.9","Cell RNA - CAPAN-2 [nTPM]":"62.6","Cell RNA - Daudi [nTPM]":"22.7","Cell RNA - EFO-21 [nTPM]":"118.0","Cell RNA - fHDF\/TERT166 [nTPM]":"35.2","Cell RNA - GAMG [nTPM]":"49.2","Cell RNA - HaCaT [nTPM]":"95.9","Cell RNA - HAP1 [nTPM]":"16.8","Cell RNA - HBEC3-KT [nTPM]":"43.5","Cell RNA - HBF TERT88 [nTPM]":"37.0","Cell RNA - HDLM-2 [nTPM]":"30.1","Cell RNA - HEK 293 [nTPM]":"19.3","Cell RNA - HEL [nTPM]":"38.7","Cell RNA - HeLa [nTPM]":"35.1","Cell RNA - Hep G2 [nTPM]":"42.1","Cell RNA - HHSteC [nTPM]":"40.8","Cell RNA - HL-60 [nTPM]":"25.0","Cell RNA - HMC-1 [nTPM]":"103.8","Cell RNA - HSkMC [nTPM]":"44.4","Cell RNA - hTCEpi [nTPM]":"30.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.9","Cell RNA - hTERT-HME1 [nTPM]":"29.2","Cell RNA - hTERT-RPE1 [nTPM]":"41.1","Cell RNA - HUVEC TERT2 [nTPM]":"55.6","Cell RNA - JURKAT [nTPM]":"45.0","Cell RNA - K-562 [nTPM]":"24.5","Cell RNA - Karpas-707 [nTPM]":"57.9","Cell RNA - LHCN-M2 [nTPM]":"50.4","Cell RNA - MCF7 [nTPM]":"15.4","Cell RNA - MOLT-4 [nTPM]":"89.5","Cell RNA - NB-4 [nTPM]":"32.0","Cell RNA - NTERA-2 [nTPM]":"40.2","Cell RNA - OE19 [nTPM]":"15.4","Cell RNA - PC-3 [nTPM]":"14.6","Cell RNA - REH [nTPM]":"36.4","Cell RNA - RH-30 [nTPM]":"91.6","Cell RNA - RPMI-8226 [nTPM]":"57.1","Cell RNA - RPTEC TERT1 [nTPM]":"66.6","Cell RNA - RT4 [nTPM]":"121.4","Cell RNA - SCLC-21H [nTPM]":"29.9","Cell RNA - SH-SY5Y [nTPM]":"20.3","Cell RNA - SiHa [nTPM]":"44.0","Cell RNA - SK-BR-3 [nTPM]":"52.8","Cell RNA - SK-MEL-30 [nTPM]":"73.1","Cell RNA - SuSa [nTPM]":"60.0","Cell RNA - T-47d [nTPM]":"30.4","Cell RNA - THP-1 [nTPM]":"55.0","Cell RNA - TIME [nTPM]":"41.4","Cell RNA - U-138 MG [nTPM]":"37.1","Cell RNA - U-2 OS [nTPM]":"41.2","Cell RNA - U-2197 [nTPM]":"296.6","Cell RNA - U-251 MG [nTPM]":"39.6","Cell RNA - U-266\/70 [nTPM]":"30.7","Cell RNA - U-266\/84 [nTPM]":"70.7","Cell RNA - U-698 [nTPM]":"23.5","Cell RNA - U-87 MG [nTPM]":"54.1","Cell RNA - U-937 [nTPM]":"50.8","Cell RNA - WM-115 [nTPM]":"67.3","Blood RNA - basophil [nTPM]":"30.9","Blood RNA - classical monocyte [nTPM]":"36.2","Blood RNA - eosinophil [nTPM]":"19.2","Blood RNA - gdT-cell [nTPM]":"12.8","Blood RNA - intermediate monocyte [nTPM]":"41.1","Blood RNA - MAIT T-cell [nTPM]":"19.2","Blood RNA - memory B-cell [nTPM]":"8.3","Blood RNA - memory CD4 T-cell [nTPM]":"12.7","Blood RNA - memory CD8 T-cell [nTPM]":"11.6","Blood RNA - myeloid DC [nTPM]":"23.6","Blood RNA - naive B-cell [nTPM]":"9.6","Blood RNA - naive CD4 T-cell [nTPM]":"12.7","Blood RNA - naive CD8 T-cell [nTPM]":"10.8","Blood RNA - neutrophil [nTPM]":"51.5","Blood RNA - NK-cell [nTPM]":"17.7","Blood RNA - non-classical monocyte [nTPM]":"48.6","Blood RNA - plasmacytoid DC [nTPM]":"10.2","Blood RNA - T-reg [nTPM]":"18.2","Blood RNA - total PBMC [nTPM]":"25.8","Brain RNA - amygdala [nTPM]":"11.4","Brain RNA - basal ganglia [nTPM]":"18.6","Brain RNA - cerebellum [nTPM]":"20.2","Brain RNA - cerebral cortex [nTPM]":"15.0","Brain RNA - hippocampal formation [nTPM]":"12.2","Brain RNA - hypothalamus [nTPM]":"12.7","Brain RNA - medulla oblongata [nTPM]":"18.2","Brain RNA - midbrain [nTPM]":"17.6","Brain RNA - pons [nTPM]":"17.5","Brain RNA - spinal cord [nTPM]":"13.7","Brain RNA - thalamus [nTPM]":"15.5","Brain RNA - white matter [nTPM]":"25.2","Single Cell Type RNA - Adipocytes [nTPM]":"60.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"83.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"50.8","Single Cell Type RNA - Astrocytes [nTPM]":"83.2","Single Cell Type RNA - B-cells [nTPM]":"37.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"26.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"30.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"33.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"33.0","Single Cell Type RNA - Bipolar cells [nTPM]":"22.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"61.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"40.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"46.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"80.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"35.6","Single Cell Type RNA - dendritic cells [nTPM]":"69.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"79.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"56.0","Single Cell Type RNA - Early spermatids [nTPM]":"21.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"39.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"56.4","Single Cell Type RNA - Endothelial cells [nTPM]":"72.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"36.1","Single Cell Type RNA - Erythroid cells [nTPM]":"20.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"106.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"31.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"57.8","Single Cell Type RNA - Fibroblasts [nTPM]":"36.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"53.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"74.0","Single Cell Type RNA - granulocytes [nTPM]":"30.3","Single Cell Type RNA - Granulosa cells [nTPM]":"31.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"71.4","Single Cell Type RNA - Hepatocytes [nTPM]":"36.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"63.8","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"96.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"43.6","Single Cell Type RNA - Ionocytes [nTPM]":"36.7","Single Cell Type RNA - Kupffer cells [nTPM]":"90.1","Single Cell Type RNA - Langerhans cells [nTPM]":"28.9","Single Cell Type RNA - Late spermatids [nTPM]":"19.4","Single Cell Type RNA - Leydig cells [nTPM]":"18.0","Single Cell Type RNA - Macrophages [nTPM]":"77.9","Single Cell Type RNA - Melanocytes [nTPM]":"46.2","Single Cell Type RNA - Microglial cells [nTPM]":"147.1","Single Cell Type RNA - monocytes [nTPM]":"69.0","Single Cell Type RNA - Muller glia cells [nTPM]":"30.6","Single Cell Type RNA - NK-cells [nTPM]":"44.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"75.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"377.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"48.9","Single Cell Type RNA - Paneth cells [nTPM]":"48.1","Single Cell Type RNA - Peritubular cells [nTPM]":"17.0","Single Cell Type RNA - Plasma cells [nTPM]":"51.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"89.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"45.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"41.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"33.4","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"34.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"42.8","Single Cell Type RNA - Spermatocytes [nTPM]":"20.3","Single Cell Type RNA - Spermatogonia [nTPM]":"17.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"39.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"26.5","Single Cell Type RNA - T-cells [nTPM]":"51.3","Single Cell Type RNA - Theca cells [nTPM]":"34.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"39.5","Single Cell Type RNA - Urothelial cells [nTPM]":"83.9"},{"Gene":"ADAM17","Gene synonym":["CD156B","cSVP","TACE"],"Ensembl":"ENSG00000151694","Gene description":"ADAM metallopeptidase domain 17","Uniprot":["P78536"],"Chromosome":"2","Position":"9488486-9556732","Protein class":["CD markers","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Notch signaling pathway"],"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Suprabasal keratinocytes":"154.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010738","HPA051575"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"300000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA010738":"AB_1078100","HPA051575":"AB_2681539"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.23e-5"},"Tissue RNA - adipose tissue [nTPM]":"10.3","Tissue RNA - adrenal gland [nTPM]":"5.5","Tissue RNA - amygdala [nTPM]":"8.7","Tissue RNA - appendix [nTPM]":"9.1","Tissue RNA - basal ganglia [nTPM]":"8.6","Tissue RNA - bone marrow [nTPM]":"5.8","Tissue RNA - breast [nTPM]":"10.4","Tissue RNA - cerebellum [nTPM]":"7.8","Tissue RNA - cerebral cortex [nTPM]":"10.6","Tissue RNA - cervix [nTPM]":"8.7","Tissue RNA - choroid plexus [nTPM]":"9.5","Tissue RNA - colon [nTPM]":"5.4","Tissue RNA - duodenum [nTPM]":"4.1","Tissue RNA - endometrium 1 [nTPM]":"7.2","Tissue RNA - epididymis [nTPM]":"11.4","Tissue RNA - esophagus [nTPM]":"10.0","Tissue RNA - fallopian tube [nTPM]":"6.5","Tissue RNA - gallbladder [nTPM]":"9.0","Tissue RNA - heart muscle [nTPM]":"6.7","Tissue RNA - hippocampal formation [nTPM]":"8.6","Tissue RNA - hypothalamus [nTPM]":"9.4","Tissue RNA - kidney [nTPM]":"4.7","Tissue RNA - liver [nTPM]":"4.6","Tissue RNA - lung [nTPM]":"14.6","Tissue RNA - lymph node [nTPM]":"8.5","Tissue RNA - medulla oblongata [nTPM]":"9.7","Tissue RNA - midbrain [nTPM]":"8.3","Tissue RNA - ovary [nTPM]":"8.9","Tissue RNA - pancreas [nTPM]":"4.1","Tissue RNA - parathyroid gland [nTPM]":"7.9","Tissue RNA - pituitary gland [nTPM]":"4.2","Tissue RNA - placenta [nTPM]":"20.1","Tissue RNA - pons [nTPM]":"9.4","Tissue RNA - prostate [nTPM]":"4.0","Tissue RNA - rectum [nTPM]":"6.8","Tissue RNA - retina [nTPM]":"4.5","Tissue RNA - salivary gland [nTPM]":"6.2","Tissue RNA - seminal vesicle [nTPM]":"6.3","Tissue RNA - skeletal muscle [nTPM]":"6.9","Tissue RNA - skin 1 [nTPM]":"11.1","Tissue RNA - small intestine [nTPM]":"6.1","Tissue RNA - smooth muscle [nTPM]":"8.6","Tissue RNA - spinal cord [nTPM]":"8.3","Tissue RNA - spleen [nTPM]":"9.3","Tissue RNA - stomach 1 [nTPM]":"5.1","Tissue RNA - testis [nTPM]":"9.9","Tissue RNA - thalamus [nTPM]":"9.1","Tissue RNA - thymus [nTPM]":"9.6","Tissue RNA - thyroid gland [nTPM]":"6.6","Tissue RNA - tongue [nTPM]":"6.8","Tissue RNA - tonsil [nTPM]":"12.7","Tissue RNA - urinary bladder [nTPM]":"10.4","Tissue RNA - vagina [nTPM]":"7.1","Tissue RNA - white matter [nTPM]":"10.4","Cell RNA - A-431 [nTPM]":"10.0","Cell RNA - A549 [nTPM]":"18.2","Cell RNA - AF22 [nTPM]":"23.2","Cell RNA - AN3-CA [nTPM]":"25.9","Cell RNA - ASC diff [nTPM]":"45.9","Cell RNA - ASC TERT1 [nTPM]":"34.7","Cell RNA - BEWO [nTPM]":"45.4","Cell RNA - BJ [nTPM]":"8.6","Cell RNA - BJ hTERT+ [nTPM]":"25.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.6","Cell RNA - CACO-2 [nTPM]":"19.2","Cell RNA - CAPAN-2 [nTPM]":"31.6","Cell RNA - Daudi [nTPM]":"33.4","Cell RNA - EFO-21 [nTPM]":"18.1","Cell RNA - fHDF\/TERT166 [nTPM]":"18.8","Cell RNA - GAMG [nTPM]":"42.1","Cell RNA - HaCaT [nTPM]":"21.9","Cell RNA - HAP1 [nTPM]":"16.4","Cell RNA - HBEC3-KT [nTPM]":"29.4","Cell RNA - HBF TERT88 [nTPM]":"22.6","Cell RNA - HDLM-2 [nTPM]":"8.4","Cell RNA - HEK 293 [nTPM]":"12.1","Cell RNA - HEL [nTPM]":"15.8","Cell RNA - HeLa [nTPM]":"14.7","Cell RNA - Hep G2 [nTPM]":"13.9","Cell RNA - HHSteC [nTPM]":"68.0","Cell RNA - HL-60 [nTPM]":"20.7","Cell RNA - HMC-1 [nTPM]":"17.8","Cell RNA - HSkMC [nTPM]":"41.2","Cell RNA - hTCEpi [nTPM]":"32.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.1","Cell RNA - hTERT-HME1 [nTPM]":"47.5","Cell RNA - hTERT-RPE1 [nTPM]":"26.6","Cell RNA - HUVEC TERT2 [nTPM]":"46.0","Cell RNA - JURKAT [nTPM]":"8.7","Cell RNA - K-562 [nTPM]":"30.0","Cell RNA - Karpas-707 [nTPM]":"12.3","Cell RNA - LHCN-M2 [nTPM]":"17.3","Cell RNA - MCF7 [nTPM]":"8.7","Cell RNA - MOLT-4 [nTPM]":"8.5","Cell RNA - NB-4 [nTPM]":"23.4","Cell RNA - NTERA-2 [nTPM]":"19.2","Cell RNA - OE19 [nTPM]":"13.7","Cell RNA - PC-3 [nTPM]":"4.6","Cell RNA - REH [nTPM]":"14.3","Cell RNA - RH-30 [nTPM]":"21.6","Cell RNA - RPMI-8226 [nTPM]":"20.5","Cell RNA - RPTEC TERT1 [nTPM]":"25.8","Cell RNA - RT4 [nTPM]":"18.7","Cell RNA - SCLC-21H [nTPM]":"11.7","Cell RNA - SH-SY5Y [nTPM]":"28.6","Cell RNA - SiHa [nTPM]":"14.9","Cell RNA - SK-BR-3 [nTPM]":"16.5","Cell RNA - SK-MEL-30 [nTPM]":"30.1","Cell RNA - SuSa [nTPM]":"27.0","Cell RNA - T-47d [nTPM]":"6.6","Cell RNA - THP-1 [nTPM]":"19.4","Cell RNA - TIME [nTPM]":"29.0","Cell RNA - U-138 MG [nTPM]":"25.5","Cell RNA - U-2 OS [nTPM]":"12.0","Cell RNA - U-2197 [nTPM]":"19.1","Cell RNA - U-251 MG [nTPM]":"22.1","Cell RNA - U-266\/70 [nTPM]":"15.1","Cell RNA - U-266\/84 [nTPM]":"17.5","Cell RNA - U-698 [nTPM]":"29.6","Cell RNA - U-87 MG [nTPM]":"20.2","Cell RNA - U-937 [nTPM]":"11.1","Cell RNA - WM-115 [nTPM]":"31.1","Blood RNA - basophil [nTPM]":"5.0","Blood RNA - classical monocyte [nTPM]":"3.7","Blood RNA - eosinophil [nTPM]":"2.8","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"3.7","Blood RNA - MAIT T-cell [nTPM]":"1.9","Blood RNA - memory B-cell [nTPM]":"1.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"2.3","Blood RNA - naive B-cell [nTPM]":"0.9","Blood RNA - naive CD4 T-cell [nTPM]":"0.9","Blood RNA - naive CD8 T-cell [nTPM]":"1.0","Blood RNA - neutrophil [nTPM]":"5.5","Blood RNA - NK-cell [nTPM]":"1.2","Blood RNA - non-classical monocyte [nTPM]":"2.5","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"1.1","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"8.7","Brain RNA - basal ganglia [nTPM]":"8.6","Brain RNA - cerebellum [nTPM]":"7.8","Brain RNA - cerebral cortex [nTPM]":"10.6","Brain RNA - hippocampal formation [nTPM]":"8.6","Brain RNA - hypothalamus [nTPM]":"9.4","Brain RNA - medulla oblongata [nTPM]":"9.7","Brain RNA - midbrain [nTPM]":"8.3","Brain RNA - pons [nTPM]":"9.4","Brain RNA - spinal cord [nTPM]":"8.3","Brain RNA - thalamus [nTPM]":"9.1","Brain RNA - white matter [nTPM]":"10.4","Single Cell Type RNA - Adipocytes [nTPM]":"53.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"66.9","Single Cell Type RNA - Astrocytes [nTPM]":"19.6","Single Cell Type RNA - B-cells [nTPM]":"34.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"130.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"48.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"37.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.9","Single Cell Type RNA - Bipolar cells [nTPM]":"25.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"40.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"26.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"38.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"54.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"29.8","Single Cell Type RNA - dendritic cells [nTPM]":"37.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"20.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"23.7","Single Cell Type RNA - Early spermatids [nTPM]":"72.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"30.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"32.0","Single Cell Type RNA - Endothelial cells [nTPM]":"45.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.7","Single Cell Type RNA - Erythroid cells [nTPM]":"16.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"66.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"45.1","Single Cell Type RNA - Fibroblasts [nTPM]":"44.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"51.5","Single Cell Type RNA - granulocytes [nTPM]":"30.9","Single Cell Type RNA - Granulosa cells [nTPM]":"31.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"41.4","Single Cell Type RNA - Hepatocytes [nTPM]":"13.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"34.6","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"46.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.8","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"80.4","Single Cell Type RNA - Langerhans cells [nTPM]":"84.5","Single Cell Type RNA - Late spermatids [nTPM]":"16.0","Single Cell Type RNA - Leydig cells [nTPM]":"19.0","Single Cell Type RNA - Macrophages [nTPM]":"76.9","Single Cell Type RNA - Melanocytes [nTPM]":"40.9","Single Cell Type RNA - Microglial cells [nTPM]":"42.2","Single Cell Type RNA - monocytes [nTPM]":"40.3","Single Cell Type RNA - Muller glia cells [nTPM]":"12.9","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"26.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"41.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.9","Single Cell Type RNA - Paneth cells [nTPM]":"18.3","Single Cell Type RNA - Peritubular cells [nTPM]":"16.1","Single Cell Type RNA - Plasma cells [nTPM]":"23.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"57.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"37.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"41.4","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"79.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.3","Single Cell Type RNA - Spermatocytes [nTPM]":"35.7","Single Cell Type RNA - Spermatogonia [nTPM]":"35.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"33.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"154.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"56.0","Single Cell Type RNA - T-cells [nTPM]":"30.1","Single Cell Type RNA - Theca cells [nTPM]":"17.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.4","Single Cell Type RNA - Urothelial cells [nTPM]":"104.3"},{"Gene":"ADAMTS13","Gene synonym":["C9orf8","DKFZp434C2322","FLJ42993","MGC118899","MGC118900","TTP","vWF-CP","VWFCP"],"Ensembl":"ENSG00000160323","Gene description":"ADAM metallopeptidase with thrombospondin type 1 motif 13","Uniprot":["Q76LX8"],"Chromosome":"9","Position":"133414358-133459402","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Blood coagulation","Hemostasis"],"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"liver":"63.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"16.0","Early spermatids":"19.3","Excitatory neurons":"12.4","Inhibitory neurons":"12.4","Late spermatids":"13.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042014","HPA042844","HPA052077"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":1300000000,"Blood concentration - Conc. blood MS [pg\/L]":"120000000","Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA042014":"AB_2677798","HPA042844":"AB_2678200","HPA052077":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-3"},"Tissue RNA - adipose tissue [nTPM]":"2.5","Tissue RNA - adrenal gland [nTPM]":"2.8","Tissue RNA - amygdala [nTPM]":"6.9","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"7.3","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"2.8","Tissue RNA - cerebellum [nTPM]":"7.6","Tissue RNA - cerebral cortex [nTPM]":"10.0","Tissue RNA - cervix [nTPM]":"5.0","Tissue RNA - choroid plexus [nTPM]":"5.3","Tissue RNA - colon [nTPM]":"4.3","Tissue RNA - duodenum [nTPM]":"3.2","Tissue RNA - endometrium 1 [nTPM]":"4.2","Tissue RNA - epididymis [nTPM]":"2.9","Tissue RNA - esophagus [nTPM]":"2.4","Tissue RNA - fallopian tube [nTPM]":"5.7","Tissue RNA - gallbladder [nTPM]":"1.2","Tissue RNA - heart muscle [nTPM]":"6.0","Tissue RNA - hippocampal formation [nTPM]":"7.1","Tissue RNA - hypothalamus [nTPM]":"6.2","Tissue RNA - kidney [nTPM]":"9.6","Tissue RNA - liver [nTPM]":"63.8","Tissue RNA - lung [nTPM]":"2.8","Tissue RNA - lymph node [nTPM]":"0.9","Tissue RNA - medulla oblongata [nTPM]":"7.0","Tissue RNA - midbrain [nTPM]":"6.7","Tissue RNA - ovary [nTPM]":"6.7","Tissue RNA - pancreas [nTPM]":"6.2","Tissue RNA - parathyroid gland [nTPM]":"1.5","Tissue RNA - pituitary gland [nTPM]":"12.5","Tissue RNA - placenta [nTPM]":"0.8","Tissue RNA - pons [nTPM]":"7.1","Tissue RNA - prostate [nTPM]":"6.4","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"1.1","Tissue RNA - salivary gland [nTPM]":"2.5","Tissue RNA - seminal vesicle [nTPM]":"1.4","Tissue RNA - skeletal muscle [nTPM]":"4.3","Tissue RNA - skin 1 [nTPM]":"2.6","Tissue RNA - small intestine [nTPM]":"4.4","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"6.3","Tissue RNA - spleen [nTPM]":"2.6","Tissue RNA - stomach 1 [nTPM]":"9.8","Tissue RNA - testis [nTPM]":"13.5","Tissue RNA - thalamus [nTPM]":"7.2","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"6.1","Tissue RNA - tongue [nTPM]":"1.4","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"4.4","Tissue RNA - vagina [nTPM]":"3.1","Tissue RNA - white matter [nTPM]":"7.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"1.9","Cell RNA - AN3-CA [nTPM]":"2.6","Cell RNA - ASC diff [nTPM]":"1.5","Cell RNA - ASC TERT1 [nTPM]":"1.3","Cell RNA - BEWO [nTPM]":"0.8","Cell RNA - BJ [nTPM]":"0.7","Cell RNA - BJ hTERT+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"2.1","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.9","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"1.2","Cell RNA - HEK 293 [nTPM]":"1.7","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.9","Cell RNA - Hep G2 [nTPM]":"0.4","Cell RNA - HHSteC [nTPM]":"1.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.7","Cell RNA - HSkMC [nTPM]":"3.6","Cell RNA - hTCEpi [nTPM]":"0.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.7","Cell RNA - hTERT-RPE1 [nTPM]":"1.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"1.3","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"0.3","Cell RNA - MCF7 [nTPM]":"3.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.9","Cell RNA - NTERA-2 [nTPM]":"2.0","Cell RNA - OE19 [nTPM]":"1.1","Cell RNA - PC-3 [nTPM]":"1.1","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.9","Cell RNA - RPTEC TERT1 [nTPM]":"0.8","Cell RNA - RT4 [nTPM]":"0.8","Cell RNA - SCLC-21H [nTPM]":"1.3","Cell RNA - SH-SY5Y [nTPM]":"4.0","Cell RNA - SiHa [nTPM]":"1.4","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"1.2","Cell RNA - SuSa [nTPM]":"3.9","Cell RNA - T-47d [nTPM]":"3.7","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"0.5","Cell RNA - U-138 MG [nTPM]":"1.5","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"0.9","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"1.7","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"1.1","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"1.6","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"6.9","Brain RNA - basal ganglia [nTPM]":"7.3","Brain RNA - cerebellum [nTPM]":"7.6","Brain RNA - cerebral cortex [nTPM]":"10.0","Brain RNA - hippocampal formation [nTPM]":"7.1","Brain RNA - hypothalamus [nTPM]":"6.2","Brain RNA - medulla oblongata [nTPM]":"7.0","Brain RNA - midbrain [nTPM]":"6.7","Brain RNA - pons [nTPM]":"7.1","Brain RNA - spinal cord [nTPM]":"6.3","Brain RNA - thalamus [nTPM]":"7.2","Brain RNA - white matter [nTPM]":"7.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.0","Single Cell Type RNA - Astrocytes [nTPM]":"16.0","Single Cell Type RNA - B-cells [nTPM]":"1.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"2.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.6","Single Cell Type RNA - Early spermatids [nTPM]":"19.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"1.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"1.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"13.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"3.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"6.0","Single Cell Type RNA - Spermatogonia [nTPM]":"3.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"1.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.9","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"ADAMTS2","Gene synonym":["ADAM-TS2","ADAMTS-3","hPCPNI","NPI","PCINP"],"Ensembl":"ENSG00000087116","Gene description":"ADAM metallopeptidase with thrombospondin type 1 motif 2","Uniprot":["O95450"],"Chromosome":"5","Position":"179110853-179345461","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted secreted proteins"],"Biological process":["Collagen degradation"],"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Ehlers-Danlos syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"32.2","Excitatory neurons":"17.9","Fibroblasts":"30.7","Hepatic stellate cells":"17.2","Kupffer cells":"71.4","Sertoli cells":"26.3","Smooth muscle cells":"20.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"36.0","ASC TERT1":"35.8","BJ":"31.4","fHDF\/TERT166":"39.3","HHSteC":"115.5","HSkMC":"94.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028363","HPA028444"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA028363":null,"HPA028444":"AB_10601964"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.71e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Tissue RNA - adipose tissue [nTPM]":"36.9","Tissue RNA - adrenal gland [nTPM]":"10.9","Tissue RNA - amygdala [nTPM]":"0.8","Tissue RNA - appendix [nTPM]":"2.4","Tissue RNA - basal ganglia [nTPM]":"4.2","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"22.7","Tissue RNA - cerebellum [nTPM]":"0.9","Tissue RNA - cerebral cortex [nTPM]":"3.5","Tissue RNA - cervix [nTPM]":"20.6","Tissue RNA - choroid plexus [nTPM]":"0.9","Tissue RNA - colon [nTPM]":"10.5","Tissue RNA - duodenum [nTPM]":"1.4","Tissue RNA - endometrium 1 [nTPM]":"21.7","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"5.5","Tissue RNA - fallopian tube [nTPM]":"15.5","Tissue RNA - gallbladder [nTPM]":"6.1","Tissue RNA - heart muscle [nTPM]":"22.3","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.9","Tissue RNA - kidney [nTPM]":"7.5","Tissue RNA - liver [nTPM]":"15.8","Tissue RNA - lung [nTPM]":"29.6","Tissue RNA - lymph node [nTPM]":"1.8","Tissue RNA - medulla oblongata [nTPM]":"4.5","Tissue RNA - midbrain [nTPM]":"3.3","Tissue RNA - ovary [nTPM]":"12.1","Tissue RNA - pancreas [nTPM]":"5.8","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"15.1","Tissue RNA - placenta [nTPM]":"9.7","Tissue RNA - pons [nTPM]":"4.2","Tissue RNA - prostate [nTPM]":"9.0","Tissue RNA - rectum [nTPM]":"1.4","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"5.3","Tissue RNA - seminal vesicle [nTPM]":"1.8","Tissue RNA - skeletal muscle [nTPM]":"2.9","Tissue RNA - skin 1 [nTPM]":"9.4","Tissue RNA - small intestine [nTPM]":"11.6","Tissue RNA - smooth muscle [nTPM]":"9.1","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"38.4","Tissue RNA - stomach 1 [nTPM]":"9.3","Tissue RNA - testis [nTPM]":"3.9","Tissue RNA - thalamus [nTPM]":"2.5","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"6.8","Tissue RNA - tongue [nTPM]":"0.8","Tissue RNA - tonsil [nTPM]":"0.6","Tissue RNA - urinary bladder [nTPM]":"15.0","Tissue RNA - vagina [nTPM]":"16.7","Tissue RNA - white matter [nTPM]":"2.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.7","Cell RNA - ASC diff [nTPM]":"36.0","Cell RNA - ASC TERT1 [nTPM]":"35.8","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"31.4","Cell RNA - BJ hTERT+ [nTPM]":"5.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.4","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"39.3","Cell RNA - GAMG [nTPM]":"0.7","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"1.8","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"5.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.5","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"2.3","Cell RNA - HHSteC [nTPM]":"115.5","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"94.4","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.3","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"8.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"5.9","Cell RNA - SH-SY5Y [nTPM]":"1.2","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"1.9","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"10.7","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"19.1","Cell RNA - U-2 OS [nTPM]":"3.0","Cell RNA - U-2197 [nTPM]":"24.5","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.9","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.8","Brain RNA - basal ganglia [nTPM]":"4.2","Brain RNA - cerebellum [nTPM]":"0.9","Brain RNA - cerebral cortex [nTPM]":"3.5","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.9","Brain RNA - medulla oblongata [nTPM]":"4.5","Brain RNA - midbrain [nTPM]":"3.3","Brain RNA - pons [nTPM]":"4.2","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"2.5","Brain RNA - white matter [nTPM]":"2.2","Single Cell Type RNA - Adipocytes [nTPM]":"3.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"32.2","Single Cell Type RNA - Endothelial cells [nTPM]":"1.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"30.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.8","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"6.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"71.4","Single Cell Type RNA - Langerhans cells [nTPM]":"4.4","Single Cell Type RNA - Late spermatids [nTPM]":"3.4","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"10.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"0.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"12.8","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.4","Single Cell Type RNA - Spermatocytes [nTPM]":"2.1","Single Cell Type RNA - Spermatogonia [nTPM]":"4.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"ADAR","Gene synonym":["ADAR1","G1P1","IFI4"],"Ensembl":"ENSG00000160710","Gene description":"Adenosine deaminase RNA specific","Uniprot":["P55265"],"Chromosome":"1","Position":"154581695-154628013","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Antiviral defense","Immunity","Innate immunity","mRNA processing","RNA-mediated gene silencing"],"Molecular function":["DNA-binding","Hydrolase","RNA-binding"],"Disease involvement":["Aicardi-Goutieres syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003890","HPA051519","CAB056157"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB056157":"AB_2665578","HPA003890":"AB_1078103","HPA051519":"AB_2681520"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.30e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Tissue RNA - adipose tissue [nTPM]":"41.9","Tissue RNA - adrenal gland [nTPM]":"44.7","Tissue RNA - amygdala [nTPM]":"30.4","Tissue RNA - appendix [nTPM]":"57.2","Tissue RNA - basal ganglia [nTPM]":"29.9","Tissue RNA - bone marrow [nTPM]":"47.1","Tissue RNA - breast [nTPM]":"41.1","Tissue RNA - cerebellum [nTPM]":"18.0","Tissue RNA - cerebral cortex [nTPM]":"35.1","Tissue RNA - cervix [nTPM]":"49.4","Tissue RNA - choroid plexus [nTPM]":"16.3","Tissue RNA - colon [nTPM]":"42.9","Tissue RNA - duodenum [nTPM]":"46.4","Tissue RNA - endometrium 1 [nTPM]":"50.2","Tissue RNA - epididymis [nTPM]":"26.3","Tissue RNA - esophagus [nTPM]":"37.9","Tissue RNA - fallopian tube [nTPM]":"50.3","Tissue RNA - gallbladder [nTPM]":"45.6","Tissue RNA - heart muscle [nTPM]":"36.1","Tissue RNA - hippocampal formation [nTPM]":"31.5","Tissue RNA - hypothalamus [nTPM]":"40.0","Tissue RNA - kidney [nTPM]":"51.7","Tissue RNA - liver [nTPM]":"56.1","Tissue RNA - lung [nTPM]":"54.6","Tissue RNA - lymph node [nTPM]":"66.1","Tissue RNA - medulla oblongata [nTPM]":"32.1","Tissue RNA - midbrain [nTPM]":"33.8","Tissue RNA - ovary [nTPM]":"54.9","Tissue RNA - pancreas [nTPM]":"40.6","Tissue RNA - parathyroid gland [nTPM]":"62.8","Tissue RNA - pituitary gland [nTPM]":"53.9","Tissue RNA - placenta [nTPM]":"46.5","Tissue RNA - pons [nTPM]":"34.8","Tissue RNA - prostate [nTPM]":"42.8","Tissue RNA - rectum [nTPM]":"44.4","Tissue RNA - retina [nTPM]":"47.9","Tissue RNA - salivary gland [nTPM]":"59.4","Tissue RNA - seminal vesicle [nTPM]":"43.0","Tissue RNA - skeletal muscle [nTPM]":"18.8","Tissue RNA - skin 1 [nTPM]":"39.9","Tissue RNA - small intestine [nTPM]":"52.8","Tissue RNA - smooth muscle [nTPM]":"56.6","Tissue RNA - spinal cord [nTPM]":"39.2","Tissue RNA - spleen [nTPM]":"73.5","Tissue RNA - stomach 1 [nTPM]":"40.3","Tissue RNA - testis [nTPM]":"34.4","Tissue RNA - thalamus [nTPM]":"37.8","Tissue RNA - thymus [nTPM]":"85.2","Tissue RNA - thyroid gland [nTPM]":"47.1","Tissue RNA - tongue [nTPM]":"27.6","Tissue RNA - tonsil [nTPM]":"65.0","Tissue RNA - urinary bladder [nTPM]":"50.5","Tissue RNA - vagina [nTPM]":"40.0","Tissue RNA - white matter [nTPM]":"25.5","Cell RNA - A-431 [nTPM]":"93.2","Cell RNA - A549 [nTPM]":"103.1","Cell RNA - AF22 [nTPM]":"84.4","Cell RNA - AN3-CA [nTPM]":"104.8","Cell RNA - ASC diff [nTPM]":"87.4","Cell RNA - ASC TERT1 [nTPM]":"88.5","Cell RNA - BEWO [nTPM]":"97.8","Cell RNA - BJ [nTPM]":"59.5","Cell RNA - BJ hTERT+ [nTPM]":"132.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"209.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"183.4","Cell RNA - CACO-2 [nTPM]":"87.8","Cell RNA - CAPAN-2 [nTPM]":"85.3","Cell RNA - Daudi [nTPM]":"162.6","Cell RNA - EFO-21 [nTPM]":"97.7","Cell RNA - fHDF\/TERT166 [nTPM]":"98.7","Cell RNA - GAMG [nTPM]":"112.4","Cell RNA - HaCaT [nTPM]":"85.4","Cell RNA - HAP1 [nTPM]":"111.9","Cell RNA - HBEC3-KT [nTPM]":"115.5","Cell RNA - HBF TERT88 [nTPM]":"109.8","Cell RNA - HDLM-2 [nTPM]":"159.1","Cell RNA - HEK 293 [nTPM]":"52.3","Cell RNA - HEL [nTPM]":"84.9","Cell RNA - HeLa [nTPM]":"66.2","Cell RNA - Hep G2 [nTPM]":"48.4","Cell RNA - HHSteC [nTPM]":"96.7","Cell RNA - HL-60 [nTPM]":"122.8","Cell RNA - HMC-1 [nTPM]":"83.8","Cell RNA - HSkMC [nTPM]":"86.2","Cell RNA - hTCEpi [nTPM]":"84.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"100.4","Cell RNA - hTERT-HME1 [nTPM]":"104.1","Cell RNA - hTERT-RPE1 [nTPM]":"81.2","Cell RNA - HUVEC TERT2 [nTPM]":"104.5","Cell RNA - JURKAT [nTPM]":"112.4","Cell RNA - K-562 [nTPM]":"82.4","Cell RNA - Karpas-707 [nTPM]":"111.6","Cell RNA - LHCN-M2 [nTPM]":"72.0","Cell RNA - MCF7 [nTPM]":"107.8","Cell RNA - MOLT-4 [nTPM]":"165.0","Cell RNA - NB-4 [nTPM]":"43.3","Cell RNA - NTERA-2 [nTPM]":"139.7","Cell RNA - OE19 [nTPM]":"125.5","Cell RNA - PC-3 [nTPM]":"74.6","Cell RNA - REH [nTPM]":"140.1","Cell RNA - RH-30 [nTPM]":"74.2","Cell RNA - RPMI-8226 [nTPM]":"131.2","Cell RNA - RPTEC TERT1 [nTPM]":"67.6","Cell RNA - RT4 [nTPM]":"106.1","Cell RNA - SCLC-21H [nTPM]":"84.8","Cell RNA - SH-SY5Y [nTPM]":"100.2","Cell RNA - SiHa [nTPM]":"104.4","Cell RNA - SK-BR-3 [nTPM]":"167.9","Cell RNA - SK-MEL-30 [nTPM]":"126.2","Cell RNA - SuSa [nTPM]":"128.1","Cell RNA - T-47d [nTPM]":"113.4","Cell RNA - THP-1 [nTPM]":"148.2","Cell RNA - TIME [nTPM]":"94.3","Cell RNA - U-138 MG [nTPM]":"67.5","Cell RNA - U-2 OS [nTPM]":"68.5","Cell RNA - U-2197 [nTPM]":"58.8","Cell RNA - U-251 MG [nTPM]":"71.5","Cell RNA - U-266\/70 [nTPM]":"132.9","Cell RNA - U-266\/84 [nTPM]":"179.0","Cell RNA - U-698 [nTPM]":"177.6","Cell RNA - U-87 MG [nTPM]":"70.2","Cell RNA - U-937 [nTPM]":"78.4","Cell RNA - WM-115 [nTPM]":"81.0","Blood RNA - basophil [nTPM]":"7.8","Blood RNA - classical monocyte [nTPM]":"8.1","Blood RNA - eosinophil [nTPM]":"15.0","Blood RNA - gdT-cell [nTPM]":"10.8","Blood RNA - intermediate monocyte [nTPM]":"9.9","Blood RNA - MAIT T-cell [nTPM]":"10.2","Blood RNA - memory B-cell [nTPM]":"9.0","Blood RNA - memory CD4 T-cell [nTPM]":"10.6","Blood RNA - memory CD8 T-cell [nTPM]":"11.2","Blood RNA - myeloid DC [nTPM]":"7.8","Blood RNA - naive B-cell [nTPM]":"5.8","Blood RNA - naive CD4 T-cell [nTPM]":"9.8","Blood RNA - naive CD8 T-cell [nTPM]":"10.0","Blood RNA - neutrophil [nTPM]":"29.1","Blood RNA - NK-cell [nTPM]":"8.6","Blood RNA - non-classical monocyte [nTPM]":"9.4","Blood RNA - plasmacytoid DC [nTPM]":"6.3","Blood RNA - T-reg [nTPM]":"9.1","Blood RNA - total PBMC [nTPM]":"7.4","Brain RNA - amygdala [nTPM]":"30.4","Brain RNA - basal ganglia [nTPM]":"29.9","Brain RNA - cerebellum [nTPM]":"18.0","Brain RNA - cerebral cortex [nTPM]":"35.1","Brain RNA - hippocampal formation [nTPM]":"31.5","Brain RNA - hypothalamus [nTPM]":"40.0","Brain RNA - medulla oblongata [nTPM]":"32.1","Brain RNA - midbrain [nTPM]":"33.8","Brain RNA - pons [nTPM]":"34.8","Brain RNA - spinal cord [nTPM]":"39.2","Brain RNA - thalamus [nTPM]":"37.8","Brain RNA - white matter [nTPM]":"25.5","Single Cell Type RNA - Adipocytes [nTPM]":"73.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"83.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"51.2","Single Cell Type RNA - Astrocytes [nTPM]":"37.5","Single Cell Type RNA - B-cells [nTPM]":"80.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"33.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"39.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"39.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"32.5","Single Cell Type RNA - Bipolar cells [nTPM]":"94.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"43.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"36.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"22.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"45.8","Single Cell Type RNA - Club cells [nTPM]":"44.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"47.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"95.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"41.2","Single Cell Type RNA - dendritic cells [nTPM]":"103.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"73.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"49.2","Single Cell Type RNA - Early spermatids [nTPM]":"4.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"48.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"61.0","Single Cell Type RNA - Endothelial cells [nTPM]":"86.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"63.1","Single Cell Type RNA - Erythroid cells [nTPM]":"45.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"44.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"66.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"57.8","Single Cell Type RNA - Fibroblasts [nTPM]":"49.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"56.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"52.4","Single Cell Type RNA - granulocytes [nTPM]":"62.1","Single Cell Type RNA - Granulosa cells [nTPM]":"88.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"84.9","Single Cell Type RNA - Hepatocytes [nTPM]":"93.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"53.5","Single Cell Type RNA - Horizontal cells [nTPM]":"168.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"53.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"53.9","Single Cell Type RNA - Ionocytes [nTPM]":"34.6","Single Cell Type RNA - Kupffer cells [nTPM]":"104.1","Single Cell Type RNA - Langerhans cells [nTPM]":"43.9","Single Cell Type RNA - Late spermatids [nTPM]":"13.1","Single Cell Type RNA - Leydig cells [nTPM]":"73.7","Single Cell Type RNA - Macrophages [nTPM]":"78.0","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"32.8","Single Cell Type RNA - monocytes [nTPM]":"110.2","Single Cell Type RNA - Muller glia cells [nTPM]":"37.9","Single Cell Type RNA - NK-cells [nTPM]":"126.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"38.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"39.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"69.6","Single Cell Type RNA - Paneth cells [nTPM]":"62.7","Single Cell Type RNA - Peritubular cells [nTPM]":"59.0","Single Cell Type RNA - Plasma cells [nTPM]":"87.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"61.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"86.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"42.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"50.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"80.2","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"40.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"45.2","Single Cell Type RNA - Spermatocytes [nTPM]":"11.4","Single Cell Type RNA - Spermatogonia [nTPM]":"35.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"37.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"40.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"31.5","Single Cell Type RNA - T-cells [nTPM]":"85.6","Single Cell Type RNA - Theca cells [nTPM]":"66.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"56.2","Single Cell Type RNA - Urothelial cells [nTPM]":"53.8"},{"Gene":"ADARB1","Gene synonym":["ADAR2","ADAR2a","ADAR2a-L1","ADAR2a-L2","ADAR2a-L3","ADAR2b","ADAR2c","ADAR2d","ADAR2g","DRABA2","DRADA2","hRED1","RED1"],"Ensembl":"ENSG00000197381","Gene description":"Adenosine deaminase RNA specific B1","Uniprot":["P78563"],"Chromosome":"21","Position":"45073853-45226560","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Antiviral defense","Immunity","Innate immunity","mRNA processing"],"Molecular function":["Hydrolase","RNA-binding"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"62.9","Excitatory neurons":"54.1","Horizontal cells":"69.0","Inhibitory neurons":"85.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"65.8","HHSteC":"65.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029645"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA029645":"AB_10602106"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.16e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.56e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.4","Tissue RNA - adrenal gland [nTPM]":"7.0","Tissue RNA - amygdala [nTPM]":"14.9","Tissue RNA - appendix [nTPM]":"10.3","Tissue RNA - basal ganglia [nTPM]":"13.2","Tissue RNA - bone marrow [nTPM]":"5.2","Tissue RNA - breast [nTPM]":"11.4","Tissue RNA - cerebellum [nTPM]":"39.1","Tissue RNA - cerebral cortex [nTPM]":"26.5","Tissue RNA - cervix [nTPM]":"14.7","Tissue RNA - choroid plexus [nTPM]":"29.6","Tissue RNA - colon [nTPM]":"35.7","Tissue RNA - duodenum [nTPM]":"3.0","Tissue RNA - endometrium 1 [nTPM]":"23.0","Tissue RNA - epididymis [nTPM]":"6.3","Tissue RNA - esophagus [nTPM]":"7.4","Tissue RNA - fallopian tube [nTPM]":"13.6","Tissue RNA - gallbladder [nTPM]":"8.1","Tissue RNA - heart muscle [nTPM]":"10.1","Tissue RNA - hippocampal formation [nTPM]":"20.0","Tissue RNA - hypothalamus [nTPM]":"17.9","Tissue RNA - kidney [nTPM]":"9.5","Tissue RNA - liver [nTPM]":"7.0","Tissue RNA - lung [nTPM]":"35.2","Tissue RNA - lymph node [nTPM]":"13.4","Tissue RNA - medulla oblongata [nTPM]":"30.6","Tissue RNA - midbrain [nTPM]":"17.2","Tissue RNA - ovary [nTPM]":"7.8","Tissue RNA - pancreas [nTPM]":"6.1","Tissue RNA - parathyroid gland [nTPM]":"9.3","Tissue RNA - pituitary gland [nTPM]":"6.1","Tissue RNA - placenta [nTPM]":"12.3","Tissue RNA - pons [nTPM]":"30.8","Tissue RNA - prostate [nTPM]":"17.9","Tissue RNA - rectum [nTPM]":"4.8","Tissue RNA - retina [nTPM]":"28.6","Tissue RNA - salivary gland [nTPM]":"6.8","Tissue RNA - seminal vesicle [nTPM]":"8.1","Tissue RNA - skeletal muscle [nTPM]":"13.6","Tissue RNA - skin 1 [nTPM]":"15.9","Tissue RNA - small intestine [nTPM]":"10.8","Tissue RNA - smooth muscle [nTPM]":"11.7","Tissue RNA - spinal cord [nTPM]":"8.7","Tissue RNA - spleen [nTPM]":"16.1","Tissue RNA - stomach 1 [nTPM]":"19.0","Tissue RNA - testis [nTPM]":"4.5","Tissue RNA - thalamus [nTPM]":"22.7","Tissue RNA - thymus [nTPM]":"5.7","Tissue RNA - thyroid gland [nTPM]":"6.6","Tissue RNA - tongue [nTPM]":"11.8","Tissue RNA - tonsil [nTPM]":"8.7","Tissue RNA - urinary bladder [nTPM]":"60.4","Tissue RNA - vagina [nTPM]":"11.9","Tissue RNA - white matter [nTPM]":"12.7","Cell RNA - A-431 [nTPM]":"7.0","Cell RNA - A549 [nTPM]":"1.0","Cell RNA - AF22 [nTPM]":"5.3","Cell RNA - AN3-CA [nTPM]":"6.2","Cell RNA - ASC diff [nTPM]":"6.3","Cell RNA - ASC TERT1 [nTPM]":"4.3","Cell RNA - BEWO [nTPM]":"7.2","Cell RNA - BJ [nTPM]":"4.6","Cell RNA - BJ hTERT+ [nTPM]":"7.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.0","Cell RNA - CACO-2 [nTPM]":"10.9","Cell RNA - CAPAN-2 [nTPM]":"1.1","Cell RNA - Daudi [nTPM]":"2.2","Cell RNA - EFO-21 [nTPM]":"12.1","Cell RNA - fHDF\/TERT166 [nTPM]":"22.6","Cell RNA - GAMG [nTPM]":"7.9","Cell RNA - HaCaT [nTPM]":"0.6","Cell RNA - HAP1 [nTPM]":"7.8","Cell RNA - HBEC3-KT [nTPM]":"19.1","Cell RNA - HBF TERT88 [nTPM]":"15.9","Cell RNA - HDLM-2 [nTPM]":"1.7","Cell RNA - HEK 293 [nTPM]":"7.0","Cell RNA - HEL [nTPM]":"15.2","Cell RNA - HeLa [nTPM]":"65.8","Cell RNA - Hep G2 [nTPM]":"7.2","Cell RNA - HHSteC [nTPM]":"65.7","Cell RNA - HL-60 [nTPM]":"10.5","Cell RNA - HMC-1 [nTPM]":"7.2","Cell RNA - HSkMC [nTPM]":"23.7","Cell RNA - hTCEpi [nTPM]":"8.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.1","Cell RNA - hTERT-HME1 [nTPM]":"14.9","Cell RNA - hTERT-RPE1 [nTPM]":"5.4","Cell RNA - HUVEC TERT2 [nTPM]":"15.4","Cell RNA - JURKAT [nTPM]":"20.4","Cell RNA - K-562 [nTPM]":"3.5","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"42.2","Cell RNA - MCF7 [nTPM]":"5.1","Cell RNA - MOLT-4 [nTPM]":"6.8","Cell RNA - NB-4 [nTPM]":"10.0","Cell RNA - NTERA-2 [nTPM]":"8.6","Cell RNA - OE19 [nTPM]":"3.4","Cell RNA - PC-3 [nTPM]":"10.1","Cell RNA - REH [nTPM]":"2.0","Cell RNA - RH-30 [nTPM]":"5.0","Cell RNA - RPMI-8226 [nTPM]":"7.1","Cell RNA - RPTEC TERT1 [nTPM]":"3.2","Cell RNA - RT4 [nTPM]":"2.3","Cell RNA - SCLC-21H [nTPM]":"30.6","Cell RNA - SH-SY5Y [nTPM]":"8.2","Cell RNA - SiHa [nTPM]":"36.4","Cell RNA - SK-BR-3 [nTPM]":"1.6","Cell RNA - SK-MEL-30 [nTPM]":"11.6","Cell RNA - SuSa [nTPM]":"8.5","Cell RNA - T-47d [nTPM]":"3.5","Cell RNA - THP-1 [nTPM]":"8.2","Cell RNA - TIME [nTPM]":"16.3","Cell RNA - U-138 MG [nTPM]":"4.7","Cell RNA - U-2 OS [nTPM]":"5.7","Cell RNA - U-2197 [nTPM]":"19.4","Cell RNA - U-251 MG [nTPM]":"17.5","Cell RNA - U-266\/70 [nTPM]":"6.6","Cell RNA - U-266\/84 [nTPM]":"3.1","Cell RNA - U-698 [nTPM]":"1.8","Cell RNA - U-87 MG [nTPM]":"4.3","Cell RNA - U-937 [nTPM]":"24.1","Cell RNA - WM-115 [nTPM]":"25.8","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"2.4","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"1.0","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"2.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"14.9","Brain RNA - basal ganglia [nTPM]":"13.2","Brain RNA - cerebellum [nTPM]":"39.1","Brain RNA - cerebral cortex [nTPM]":"26.5","Brain RNA - hippocampal formation [nTPM]":"20.0","Brain RNA - hypothalamus [nTPM]":"17.9","Brain RNA - medulla oblongata [nTPM]":"30.6","Brain RNA - midbrain [nTPM]":"17.2","Brain RNA - pons [nTPM]":"30.8","Brain RNA - spinal cord [nTPM]":"8.7","Brain RNA - thalamus [nTPM]":"22.7","Brain RNA - white matter [nTPM]":"12.7","Single Cell Type RNA - Adipocytes [nTPM]":"29.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"12.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"62.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"21.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"1.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"5.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.3","Single Cell Type RNA - Early spermatids [nTPM]":"2.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.8","Single Cell Type RNA - Endothelial cells [nTPM]":"21.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"54.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.2","Single Cell Type RNA - Fibroblasts [nTPM]":"9.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.6","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"5.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.3","Single Cell Type RNA - Hepatocytes [nTPM]":"6.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.9","Single Cell Type RNA - Horizontal cells [nTPM]":"69.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"85.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.4","Single Cell Type RNA - Langerhans cells [nTPM]":"4.9","Single Cell Type RNA - Late spermatids [nTPM]":"2.9","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"3.2","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"37.5","Single Cell Type RNA - monocytes [nTPM]":"5.0","Single Cell Type RNA - Muller glia cells [nTPM]":"34.2","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"5.7","Single Cell Type RNA - Plasma cells [nTPM]":"4.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"32.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.7","Single Cell Type RNA - Spermatocytes [nTPM]":"11.4","Single Cell Type RNA - Spermatogonia [nTPM]":"17.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"13.7","Single Cell Type RNA - Theca cells [nTPM]":"1.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.2","Single Cell Type RNA - Urothelial cells [nTPM]":"2.3"},{"Gene":"ADCY1","Gene synonym":["AC1","DFNB44"],"Ensembl":"ENSG00000164742","Gene description":"Adenylate cyclase 1","Uniprot":["Q08828"],"Chromosome":"7","Position":"45574140-45723116","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Biological rhythms","cAMP biosynthesis"],"Molecular function":["Calmodulin-binding","Lyase"],"Disease involvement":["Cancer-related genes","Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"33.7","liver":"19.2","retina":"53.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"521.3","Excitatory neurons":"147.2","Inhibitory neurons":"117.9","Rod photoreceptor cells":"174.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTERT-HME1":"22.2","SH-SY5Y":"25.5","SK-MEL-30":"30.1","WM-115":"17.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB018364","HPA068274"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB018364":"AB_2223098","HPA068274":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.9","Tissue RNA - adrenal gland [nTPM]":"1.8","Tissue RNA - amygdala [nTPM]":"13.7","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"22.4","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"4.7","Tissue RNA - cerebellum [nTPM]":"15.4","Tissue RNA - cerebral cortex [nTPM]":"33.7","Tissue RNA - cervix [nTPM]":"5.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"1.8","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"0.6","Tissue RNA - fallopian tube [nTPM]":"2.0","Tissue RNA - gallbladder [nTPM]":"0.6","Tissue RNA - heart muscle [nTPM]":"2.9","Tissue RNA - hippocampal formation [nTPM]":"31.9","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"1.9","Tissue RNA - liver [nTPM]":"19.2","Tissue RNA - lung [nTPM]":"0.6","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"1.2","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"0.9","Tissue RNA - pancreas [nTPM]":"3.3","Tissue RNA - parathyroid gland [nTPM]":"1.9","Tissue RNA - pituitary gland [nTPM]":"2.6","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"1.1","Tissue RNA - prostate [nTPM]":"2.8","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"53.0","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"1.2","Tissue RNA - skeletal muscle [nTPM]":"7.7","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.9","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"1.7","Tissue RNA - stomach 1 [nTPM]":"1.1","Tissue RNA - testis [nTPM]":"2.8","Tissue RNA - thalamus [nTPM]":"4.0","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"2.4","Tissue RNA - tongue [nTPM]":"8.5","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"0.8","Tissue RNA - vagina [nTPM]":"1.3","Tissue RNA - white matter [nTPM]":"24.5","Cell RNA - A-431 [nTPM]":"0.8","Cell RNA - A549 [nTPM]":"5.9","Cell RNA - AF22 [nTPM]":"2.1","Cell RNA - AN3-CA [nTPM]":"3.2","Cell RNA - ASC diff [nTPM]":"4.1","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"4.0","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"0.6","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"5.8","Cell RNA - HaCaT [nTPM]":"1.9","Cell RNA - HAP1 [nTPM]":"3.8","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"10.7","Cell RNA - HEK 293 [nTPM]":"2.7","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.6","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"4.9","Cell RNA - hTCEpi [nTPM]":"2.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.5","Cell RNA - hTERT-HME1 [nTPM]":"22.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"8.6","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"7.0","Cell RNA - LHCN-M2 [nTPM]":"0.3","Cell RNA - MCF7 [nTPM]":"7.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"8.3","Cell RNA - OE19 [nTPM]":"5.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"11.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"5.7","Cell RNA - SCLC-21H [nTPM]":"13.4","Cell RNA - SH-SY5Y [nTPM]":"25.5","Cell RNA - SiHa [nTPM]":"2.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"30.1","Cell RNA - SuSa [nTPM]":"3.1","Cell RNA - T-47d [nTPM]":"2.0","Cell RNA - THP-1 [nTPM]":"3.5","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.6","Cell RNA - U-2 OS [nTPM]":"4.2","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"3.6","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"17.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"13.7","Brain RNA - basal ganglia [nTPM]":"22.4","Brain RNA - cerebellum [nTPM]":"15.4","Brain RNA - cerebral cortex [nTPM]":"33.7","Brain RNA - hippocampal formation [nTPM]":"31.9","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"1.2","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"1.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"4.0","Brain RNA - white matter [nTPM]":"24.5","Single Cell Type RNA - Adipocytes [nTPM]":"3.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"30.7","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"43.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"521.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.1","Single Cell Type RNA - Endothelial cells [nTPM]":"10.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"31.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"147.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"4.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.7","Single Cell Type RNA - Hepatocytes [nTPM]":"52.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"42.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"117.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.2","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"13.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"63.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"174.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"6.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"ADCY10","Gene synonym":["HCA2","RP1-313L4.2","SAC","SACI","Sacy"],"Ensembl":"ENSG00000143199","Gene description":"Adenylate cyclase 10","Uniprot":["Q96PN6"],"Chromosome":"1","Position":"167809386-167914215","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["cAMP biosynthesis"],"Molecular function":["Lyase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"liver":"6.1","testis":"17.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Early spermatids":"87.5","Late spermatids":"85.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"0.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"T-47d":"1.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015243","HPA017749"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA015243":"AB_1856540","HPA017749":"AB_1856541"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-5"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"1.3","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"1.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.0","Tissue RNA - cerebellum [nTPM]":"2.6","Tissue RNA - cerebral cortex [nTPM]":"2.4","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"1.4","Tissue RNA - hypothalamus [nTPM]":"0.7","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"6.1","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.6","Tissue RNA - midbrain [nTPM]":"0.8","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.7","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"17.6","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"1.7","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.7","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.3","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"1.4","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.3","Brain RNA - basal ganglia [nTPM]":"1.2","Brain RNA - cerebellum [nTPM]":"2.6","Brain RNA - cerebral cortex [nTPM]":"2.4","Brain RNA - hippocampal formation [nTPM]":"1.4","Brain RNA - hypothalamus [nTPM]":"0.7","Brain RNA - medulla oblongata [nTPM]":"0.6","Brain RNA - midbrain [nTPM]":"0.8","Brain RNA - pons [nTPM]":"0.7","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"1.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.9","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"87.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"7.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"85.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"11.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.8","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"ADCY3","Gene synonym":["AC3"],"Ensembl":"ENSG00000138031","Gene description":"Adenylate cyclase 3","Uniprot":["O60266"],"Chromosome":"2","Position":"24819169-24920237","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["cAMP biosynthesis","Olfaction","Sensory transduction"],"Molecular function":["Calmodulin-binding","Lyase"],"Disease involvement":["Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Leydig cells":"58.4","Sertoli cells":"111.7","Smooth muscle cells":"62.8","Theca cells":"92.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010223"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB010223":"AB_630839"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.32e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-3"},"Tissue RNA - adipose tissue [nTPM]":"94.4","Tissue RNA - adrenal gland [nTPM]":"17.3","Tissue RNA - amygdala [nTPM]":"43.5","Tissue RNA - appendix [nTPM]":"17.3","Tissue RNA - basal ganglia [nTPM]":"55.1","Tissue RNA - bone marrow [nTPM]":"17.7","Tissue RNA - breast [nTPM]":"74.6","Tissue RNA - cerebellum [nTPM]":"36.7","Tissue RNA - cerebral cortex [nTPM]":"50.1","Tissue RNA - cervix [nTPM]":"66.7","Tissue RNA - choroid plexus [nTPM]":"28.4","Tissue RNA - colon [nTPM]":"27.5","Tissue RNA - duodenum [nTPM]":"10.9","Tissue RNA - endometrium 1 [nTPM]":"56.4","Tissue RNA - epididymis [nTPM]":"20.5","Tissue RNA - esophagus [nTPM]":"30.4","Tissue RNA - fallopian tube [nTPM]":"62.1","Tissue RNA - gallbladder [nTPM]":"23.0","Tissue RNA - heart muscle [nTPM]":"36.6","Tissue RNA - hippocampal formation [nTPM]":"43.3","Tissue RNA - hypothalamus [nTPM]":"43.4","Tissue RNA - kidney [nTPM]":"25.9","Tissue RNA - liver [nTPM]":"6.6","Tissue RNA - lung [nTPM]":"42.5","Tissue RNA - lymph node [nTPM]":"18.9","Tissue RNA - medulla oblongata [nTPM]":"41.6","Tissue RNA - midbrain [nTPM]":"43.8","Tissue RNA - ovary [nTPM]":"71.9","Tissue RNA - pancreas [nTPM]":"15.7","Tissue RNA - parathyroid gland [nTPM]":"17.0","Tissue RNA - pituitary gland [nTPM]":"41.7","Tissue RNA - placenta [nTPM]":"83.6","Tissue RNA - pons [nTPM]":"41.1","Tissue RNA - prostate [nTPM]":"40.6","Tissue RNA - rectum [nTPM]":"15.8","Tissue RNA - retina [nTPM]":"4.2","Tissue RNA - salivary gland [nTPM]":"21.6","Tissue RNA - seminal vesicle [nTPM]":"33.0","Tissue RNA - skeletal muscle [nTPM]":"15.2","Tissue RNA - skin 1 [nTPM]":"38.4","Tissue RNA - small intestine [nTPM]":"34.4","Tissue RNA - smooth muscle [nTPM]":"35.3","Tissue RNA - spinal cord [nTPM]":"36.9","Tissue RNA - spleen [nTPM]":"30.4","Tissue RNA - stomach 1 [nTPM]":"25.0","Tissue RNA - testis [nTPM]":"9.8","Tissue RNA - thalamus [nTPM]":"50.6","Tissue RNA - thymus [nTPM]":"11.4","Tissue RNA - thyroid gland [nTPM]":"36.8","Tissue RNA - tongue [nTPM]":"20.4","Tissue RNA - tonsil [nTPM]":"18.1","Tissue RNA - urinary bladder [nTPM]":"36.4","Tissue RNA - vagina [nTPM]":"48.9","Tissue RNA - white matter [nTPM]":"44.9","Cell RNA - A-431 [nTPM]":"76.5","Cell RNA - A549 [nTPM]":"40.4","Cell RNA - AF22 [nTPM]":"17.2","Cell RNA - AN3-CA [nTPM]":"28.3","Cell RNA - ASC diff [nTPM]":"84.5","Cell RNA - ASC TERT1 [nTPM]":"75.4","Cell RNA - BEWO [nTPM]":"29.6","Cell RNA - BJ [nTPM]":"32.3","Cell RNA - BJ hTERT+ [nTPM]":"65.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"37.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"37.8","Cell RNA - CACO-2 [nTPM]":"38.6","Cell RNA - CAPAN-2 [nTPM]":"25.1","Cell RNA - Daudi [nTPM]":"26.0","Cell RNA - EFO-21 [nTPM]":"6.2","Cell RNA - fHDF\/TERT166 [nTPM]":"53.2","Cell RNA - GAMG [nTPM]":"51.0","Cell RNA - HaCaT [nTPM]":"54.5","Cell RNA - HAP1 [nTPM]":"43.1","Cell RNA - HBEC3-KT [nTPM]":"54.5","Cell RNA - HBF TERT88 [nTPM]":"24.0","Cell RNA - HDLM-2 [nTPM]":"58.4","Cell RNA - HEK 293 [nTPM]":"55.8","Cell RNA - HEL [nTPM]":"43.0","Cell RNA - HeLa [nTPM]":"40.0","Cell RNA - Hep G2 [nTPM]":"1.7","Cell RNA - HHSteC [nTPM]":"64.0","Cell RNA - HL-60 [nTPM]":"24.0","Cell RNA - HMC-1 [nTPM]":"24.6","Cell RNA - HSkMC [nTPM]":"55.7","Cell RNA - hTCEpi [nTPM]":"47.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"36.6","Cell RNA - hTERT-HME1 [nTPM]":"50.8","Cell RNA - hTERT-RPE1 [nTPM]":"23.6","Cell RNA - HUVEC TERT2 [nTPM]":"33.8","Cell RNA - JURKAT [nTPM]":"27.9","Cell RNA - K-562 [nTPM]":"15.5","Cell RNA - Karpas-707 [nTPM]":"49.2","Cell RNA - LHCN-M2 [nTPM]":"19.3","Cell RNA - MCF7 [nTPM]":"43.6","Cell RNA - MOLT-4 [nTPM]":"17.9","Cell RNA - NB-4 [nTPM]":"2.1","Cell RNA - NTERA-2 [nTPM]":"14.9","Cell RNA - OE19 [nTPM]":"39.9","Cell RNA - PC-3 [nTPM]":"24.4","Cell RNA - REH [nTPM]":"38.8","Cell RNA - RH-30 [nTPM]":"75.3","Cell RNA - RPMI-8226 [nTPM]":"59.5","Cell RNA - RPTEC TERT1 [nTPM]":"15.5","Cell RNA - RT4 [nTPM]":"38.7","Cell RNA - SCLC-21H [nTPM]":"31.6","Cell RNA - SH-SY5Y [nTPM]":"19.1","Cell RNA - SiHa [nTPM]":"45.8","Cell RNA - SK-BR-3 [nTPM]":"54.2","Cell RNA - SK-MEL-30 [nTPM]":"30.2","Cell RNA - SuSa [nTPM]":"13.0","Cell RNA - T-47d [nTPM]":"13.5","Cell RNA - THP-1 [nTPM]":"22.5","Cell RNA - TIME [nTPM]":"33.5","Cell RNA - U-138 MG [nTPM]":"59.7","Cell RNA - U-2 OS [nTPM]":"34.2","Cell RNA - U-2197 [nTPM]":"39.1","Cell RNA - U-251 MG [nTPM]":"54.1","Cell RNA - U-266\/70 [nTPM]":"42.4","Cell RNA - U-266\/84 [nTPM]":"101.6","Cell RNA - U-698 [nTPM]":"113.6","Cell RNA - U-87 MG [nTPM]":"18.7","Cell RNA - U-937 [nTPM]":"39.2","Cell RNA - WM-115 [nTPM]":"31.4","Blood RNA - basophil [nTPM]":"2.6","Blood RNA - classical monocyte [nTPM]":"1.5","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"1.6","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"5.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"9.5","Blood RNA - naive B-cell [nTPM]":"6.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.2","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"9.0","Blood RNA - T-reg [nTPM]":"3.4","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"43.5","Brain RNA - basal ganglia [nTPM]":"55.1","Brain RNA - cerebellum [nTPM]":"36.7","Brain RNA - cerebral cortex [nTPM]":"50.1","Brain RNA - hippocampal formation [nTPM]":"43.3","Brain RNA - hypothalamus [nTPM]":"43.4","Brain RNA - medulla oblongata [nTPM]":"41.6","Brain RNA - midbrain [nTPM]":"43.8","Brain RNA - pons [nTPM]":"41.1","Brain RNA - spinal cord [nTPM]":"36.9","Brain RNA - thalamus [nTPM]":"50.6","Brain RNA - white matter [nTPM]":"44.9","Single Cell Type RNA - Adipocytes [nTPM]":"14.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.8","Single Cell Type RNA - Astrocytes [nTPM]":"17.0","Single Cell Type RNA - B-cells [nTPM]":"8.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"3.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - dendritic cells [nTPM]":"5.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"42.2","Single Cell Type RNA - Endothelial cells [nTPM]":"10.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"40.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.1","Single Cell Type RNA - Fibroblasts [nTPM]":"25.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.2","Single Cell Type RNA - granulocytes [nTPM]":"18.4","Single Cell Type RNA - Granulosa cells [nTPM]":"3.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"36.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"5.4","Single Cell Type RNA - Langerhans cells [nTPM]":"6.9","Single Cell Type RNA - Late spermatids [nTPM]":"3.9","Single Cell Type RNA - Leydig cells [nTPM]":"58.4","Single Cell Type RNA - Macrophages [nTPM]":"10.1","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"4.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"33.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.0","Single Cell Type RNA - Paneth cells [nTPM]":"5.8","Single Cell Type RNA - Peritubular cells [nTPM]":"29.3","Single Cell Type RNA - Plasma cells [nTPM]":"4.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.2","Single Cell Type RNA - Sertoli cells [nTPM]":"111.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"62.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"2.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - T-cells [nTPM]":"7.2","Single Cell Type RNA - Theca cells [nTPM]":"92.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.1","Single Cell Type RNA - Urothelial cells [nTPM]":"3.9"},{"Gene":"ADCY5","Gene synonym":["AC5"],"Ensembl":"ENSG00000173175","Gene description":"Adenylate cyclase 5","Uniprot":["O95622"],"Chromosome":"3","Position":"123282296-123449090","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["cAMP biosynthesis"],"Molecular function":["Lyase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"97.7","heart muscle":"105.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"75.5","Inhibitory neurons":"44.0","Oligodendrocytes":"89.7","Paneth cells":"59.6","Peritubular cells":"73.7","Sertoli cells":"65.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"15.5","RPMI-8226":"2.7","RPTEC TERT1":"5.2"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"basal ganglia":"388.0"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"basal ganglia":"155.9"},"Antibody":["HPA017730","HPA077682"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Intermediate filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Intermediate filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA017730":"AB_1844595","HPA077682":"AB_2686851"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.46e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-4"},"Tissue RNA - adipose tissue [nTPM]":"18.9","Tissue RNA - adrenal gland [nTPM]":"3.3","Tissue RNA - amygdala [nTPM]":"25.5","Tissue RNA - appendix [nTPM]":"4.9","Tissue RNA - basal ganglia [nTPM]":"97.7","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"10.6","Tissue RNA - cerebellum [nTPM]":"13.9","Tissue RNA - cerebral cortex [nTPM]":"43.9","Tissue RNA - cervix [nTPM]":"9.8","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"35.1","Tissue RNA - duodenum [nTPM]":"5.2","Tissue RNA - endometrium 1 [nTPM]":"14.7","Tissue RNA - epididymis [nTPM]":"5.7","Tissue RNA - esophagus [nTPM]":"18.8","Tissue RNA - fallopian tube [nTPM]":"12.7","Tissue RNA - gallbladder [nTPM]":"10.0","Tissue RNA - heart muscle [nTPM]":"105.2","Tissue RNA - hippocampal formation [nTPM]":"25.8","Tissue RNA - hypothalamus [nTPM]":"15.9","Tissue RNA - kidney [nTPM]":"12.8","Tissue RNA - liver [nTPM]":"3.3","Tissue RNA - lung [nTPM]":"4.1","Tissue RNA - lymph node [nTPM]":"2.3","Tissue RNA - medulla oblongata [nTPM]":"20.5","Tissue RNA - midbrain [nTPM]":"18.3","Tissue RNA - ovary [nTPM]":"13.2","Tissue RNA - pancreas [nTPM]":"7.5","Tissue RNA - parathyroid gland [nTPM]":"0.8","Tissue RNA - pituitary gland [nTPM]":"14.3","Tissue RNA - placenta [nTPM]":"6.1","Tissue RNA - pons [nTPM]":"17.4","Tissue RNA - prostate [nTPM]":"19.8","Tissue RNA - rectum [nTPM]":"5.6","Tissue RNA - retina [nTPM]":"4.5","Tissue RNA - salivary gland [nTPM]":"4.0","Tissue RNA - seminal vesicle [nTPM]":"21.5","Tissue RNA - skeletal muscle [nTPM]":"2.7","Tissue RNA - skin 1 [nTPM]":"2.6","Tissue RNA - small intestine [nTPM]":"13.0","Tissue RNA - smooth muscle [nTPM]":"18.2","Tissue RNA - spinal cord [nTPM]":"10.8","Tissue RNA - spleen [nTPM]":"6.5","Tissue RNA - stomach 1 [nTPM]":"21.2","Tissue RNA - testis [nTPM]":"8.2","Tissue RNA - thalamus [nTPM]":"34.4","Tissue RNA - thymus [nTPM]":"1.3","Tissue RNA - thyroid gland [nTPM]":"1.9","Tissue RNA - tongue [nTPM]":"5.8","Tissue RNA - tonsil [nTPM]":"3.0","Tissue RNA - urinary bladder [nTPM]":"23.2","Tissue RNA - vagina [nTPM]":"7.8","Tissue RNA - white matter [nTPM]":"30.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.6","Cell RNA - AF22 [nTPM]":"1.3","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"2.3","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"0.6","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.8","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.5","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"15.5","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"2.7","Cell RNA - RPTEC TERT1 [nTPM]":"5.2","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"1.8","Cell RNA - SH-SY5Y [nTPM]":"1.6","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"1.7","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"1.2","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"25.5","Brain RNA - basal ganglia [nTPM]":"97.7","Brain RNA - cerebellum [nTPM]":"13.9","Brain RNA - cerebral cortex [nTPM]":"43.9","Brain RNA - hippocampal formation [nTPM]":"25.8","Brain RNA - hypothalamus [nTPM]":"15.9","Brain RNA - medulla oblongata [nTPM]":"20.5","Brain RNA - midbrain [nTPM]":"18.3","Brain RNA - pons [nTPM]":"17.4","Brain RNA - spinal cord [nTPM]":"10.8","Brain RNA - thalamus [nTPM]":"34.4","Brain RNA - white matter [nTPM]":"30.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"8.1","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"21.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"75.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"15.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"34.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.0","Single Cell Type RNA - Fibroblasts [nTPM]":"5.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"4.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"44.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"3.0","Single Cell Type RNA - Leydig cells [nTPM]":"20.5","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"89.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"59.6","Single Cell Type RNA - Peritubular cells [nTPM]":"73.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.2","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"6.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.4","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"1.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"ADCY6","Gene synonym":["AC6"],"Ensembl":"ENSG00000174233","Gene description":"Adenylate cyclase 6","Uniprot":["O43306"],"Chromosome":"12","Position":"48766194-48789089","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["cAMP biosynthesis"],"Molecular function":["Lyase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"38.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SK-BR-3":"68.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB018365"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB018365":"AB_2257941"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.23e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Tissue RNA - adipose tissue [nTPM]":"43.2","Tissue RNA - adrenal gland [nTPM]":"15.0","Tissue RNA - amygdala [nTPM]":"8.9","Tissue RNA - appendix [nTPM]":"6.1","Tissue RNA - basal ganglia [nTPM]":"7.9","Tissue RNA - bone marrow [nTPM]":"1.3","Tissue RNA - breast [nTPM]":"23.7","Tissue RNA - cerebellum [nTPM]":"5.0","Tissue RNA - cerebral cortex [nTPM]":"9.2","Tissue RNA - cervix [nTPM]":"19.3","Tissue RNA - choroid plexus [nTPM]":"10.3","Tissue RNA - colon [nTPM]":"26.3","Tissue RNA - duodenum [nTPM]":"18.7","Tissue RNA - endometrium 1 [nTPM]":"20.7","Tissue RNA - epididymis [nTPM]":"19.0","Tissue RNA - esophagus [nTPM]":"10.3","Tissue RNA - fallopian tube [nTPM]":"17.1","Tissue RNA - gallbladder [nTPM]":"13.9","Tissue RNA - heart muscle [nTPM]":"57.2","Tissue RNA - hippocampal formation [nTPM]":"8.0","Tissue RNA - hypothalamus [nTPM]":"11.2","Tissue RNA - kidney [nTPM]":"21.1","Tissue RNA - liver [nTPM]":"9.6","Tissue RNA - lung [nTPM]":"13.5","Tissue RNA - lymph node [nTPM]":"3.9","Tissue RNA - medulla oblongata [nTPM]":"5.5","Tissue RNA - midbrain [nTPM]":"5.4","Tissue RNA - ovary [nTPM]":"22.3","Tissue RNA - pancreas [nTPM]":"22.3","Tissue RNA - parathyroid gland [nTPM]":"20.7","Tissue RNA - pituitary gland [nTPM]":"14.6","Tissue RNA - placenta [nTPM]":"14.5","Tissue RNA - pons [nTPM]":"6.6","Tissue RNA - prostate [nTPM]":"16.3","Tissue RNA - rectum [nTPM]":"20.3","Tissue RNA - retina [nTPM]":"5.7","Tissue RNA - salivary gland [nTPM]":"33.5","Tissue RNA - seminal vesicle [nTPM]":"16.5","Tissue RNA - skeletal muscle [nTPM]":"12.1","Tissue RNA - skin 1 [nTPM]":"15.3","Tissue RNA - small intestine [nTPM]":"21.4","Tissue RNA - smooth muscle [nTPM]":"13.6","Tissue RNA - spinal cord [nTPM]":"1.9","Tissue RNA - spleen [nTPM]":"4.8","Tissue RNA - stomach 1 [nTPM]":"25.1","Tissue RNA - testis [nTPM]":"4.0","Tissue RNA - thalamus [nTPM]":"14.4","Tissue RNA - thymus [nTPM]":"2.8","Tissue RNA - thyroid gland [nTPM]":"17.9","Tissue RNA - tongue [nTPM]":"12.7","Tissue RNA - tonsil [nTPM]":"3.2","Tissue RNA - urinary bladder [nTPM]":"12.3","Tissue RNA - vagina [nTPM]":"12.8","Tissue RNA - white matter [nTPM]":"6.4","Cell RNA - A-431 [nTPM]":"14.0","Cell RNA - A549 [nTPM]":"25.9","Cell RNA - AF22 [nTPM]":"30.2","Cell RNA - AN3-CA [nTPM]":"18.9","Cell RNA - ASC diff [nTPM]":"32.0","Cell RNA - ASC TERT1 [nTPM]":"15.9","Cell RNA - BEWO [nTPM]":"32.0","Cell RNA - BJ [nTPM]":"16.7","Cell RNA - BJ hTERT+ [nTPM]":"17.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.8","Cell RNA - CACO-2 [nTPM]":"45.7","Cell RNA - CAPAN-2 [nTPM]":"45.3","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"37.2","Cell RNA - fHDF\/TERT166 [nTPM]":"15.3","Cell RNA - GAMG [nTPM]":"8.2","Cell RNA - HaCaT [nTPM]":"10.9","Cell RNA - HAP1 [nTPM]":"9.2","Cell RNA - HBEC3-KT [nTPM]":"11.6","Cell RNA - HBF TERT88 [nTPM]":"7.9","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"13.4","Cell RNA - HEL [nTPM]":"12.5","Cell RNA - HeLa [nTPM]":"37.8","Cell RNA - Hep G2 [nTPM]":"8.4","Cell RNA - HHSteC [nTPM]":"17.6","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"10.1","Cell RNA - HSkMC [nTPM]":"20.0","Cell RNA - hTCEpi [nTPM]":"13.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"17.1","Cell RNA - hTERT-HME1 [nTPM]":"6.5","Cell RNA - hTERT-RPE1 [nTPM]":"37.9","Cell RNA - HUVEC TERT2 [nTPM]":"18.7","Cell RNA - JURKAT [nTPM]":"0.8","Cell RNA - K-562 [nTPM]":"1.7","Cell RNA - Karpas-707 [nTPM]":"4.5","Cell RNA - LHCN-M2 [nTPM]":"15.6","Cell RNA - MCF7 [nTPM]":"23.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"10.3","Cell RNA - OE19 [nTPM]":"21.6","Cell RNA - PC-3 [nTPM]":"12.3","Cell RNA - REH [nTPM]":"4.6","Cell RNA - RH-30 [nTPM]":"11.4","Cell RNA - RPMI-8226 [nTPM]":"7.7","Cell RNA - RPTEC TERT1 [nTPM]":"23.4","Cell RNA - RT4 [nTPM]":"41.5","Cell RNA - SCLC-21H [nTPM]":"4.5","Cell RNA - SH-SY5Y [nTPM]":"18.4","Cell RNA - SiHa [nTPM]":"17.2","Cell RNA - SK-BR-3 [nTPM]":"68.0","Cell RNA - SK-MEL-30 [nTPM]":"15.2","Cell RNA - SuSa [nTPM]":"13.3","Cell RNA - T-47d [nTPM]":"53.3","Cell RNA - THP-1 [nTPM]":"3.5","Cell RNA - TIME [nTPM]":"21.1","Cell RNA - U-138 MG [nTPM]":"18.3","Cell RNA - U-2 OS [nTPM]":"13.1","Cell RNA - U-2197 [nTPM]":"9.7","Cell RNA - U-251 MG [nTPM]":"7.4","Cell RNA - U-266\/70 [nTPM]":"7.0","Cell RNA - U-266\/84 [nTPM]":"3.7","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"16.9","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"8.6","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"8.9","Brain RNA - basal ganglia [nTPM]":"7.9","Brain RNA - cerebellum [nTPM]":"5.0","Brain RNA - cerebral cortex [nTPM]":"9.2","Brain RNA - hippocampal formation [nTPM]":"8.0","Brain RNA - hypothalamus [nTPM]":"11.2","Brain RNA - medulla oblongata [nTPM]":"5.5","Brain RNA - midbrain [nTPM]":"5.4","Brain RNA - pons [nTPM]":"6.6","Brain RNA - spinal cord [nTPM]":"1.9","Brain RNA - thalamus [nTPM]":"14.4","Brain RNA - white matter [nTPM]":"6.4","Single Cell Type RNA - Adipocytes [nTPM]":"11.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.4","Single Cell Type RNA - Astrocytes [nTPM]":"18.3","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"10.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"9.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"38.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.0","Single Cell Type RNA - Endothelial cells [nTPM]":"8.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.7","Single Cell Type RNA - Fibroblasts [nTPM]":"7.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.3","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"14.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"7.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.5","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.9","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"2.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.1","Single Cell Type RNA - Leydig cells [nTPM]":"11.5","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"3.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.5","Single Cell Type RNA - Paneth cells [nTPM]":"30.3","Single Cell Type RNA - Peritubular cells [nTPM]":"9.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"26.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.3","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.6","Single Cell Type RNA - Spermatocytes [nTPM]":"1.9","Single Cell Type RNA - Spermatogonia [nTPM]":"1.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.1","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"13.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.7","Single Cell Type RNA - Urothelial cells [nTPM]":"9.3"},{"Gene":"ADGRE2","Gene synonym":["CD312","EMR2"],"Ensembl":"ENSG00000127507","Gene description":"Adhesion G protein-coupled receptor E2","Uniprot":["Q9UHX3"],"Chromosome":"19","Position":"14732392-14778560","Protein class":["CD markers","Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Cell adhesion","Inflammatory response"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"19.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"granulocytes":"47.9","Kupffer cells":"69.4","Macrophages":"73.2","monocytes":"49.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"70.0","eosinophil":"74.7","intermediate monocyte":"46.9","neutrophil":"55.7","non-classical monocyte":"89.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"74.7","monocytes":"89.9"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"11.8","HMC-1":"18.3","NB-4":"11.5","RPMI-8226":"8.4","U-937":"14.9"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055200"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA055200":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.35e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Tissue RNA - adipose tissue [nTPM]":"4.9","Tissue RNA - adrenal gland [nTPM]":"1.5","Tissue RNA - amygdala [nTPM]":"1.0","Tissue RNA - appendix [nTPM]":"19.4","Tissue RNA - basal ganglia [nTPM]":"1.3","Tissue RNA - bone marrow [nTPM]":"6.9","Tissue RNA - breast [nTPM]":"1.8","Tissue RNA - cerebellum [nTPM]":"1.2","Tissue RNA - cerebral cortex [nTPM]":"2.1","Tissue RNA - cervix [nTPM]":"0.9","Tissue RNA - choroid plexus [nTPM]":"1.3","Tissue RNA - colon [nTPM]":"1.4","Tissue RNA - duodenum [nTPM]":"1.9","Tissue RNA - endometrium 1 [nTPM]":"0.7","Tissue RNA - epididymis [nTPM]":"0.7","Tissue RNA - esophagus [nTPM]":"0.9","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"2.5","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"1.0","Tissue RNA - hypothalamus [nTPM]":"1.5","Tissue RNA - kidney [nTPM]":"2.1","Tissue RNA - liver [nTPM]":"2.0","Tissue RNA - lung [nTPM]":"4.2","Tissue RNA - lymph node [nTPM]":"3.0","Tissue RNA - medulla oblongata [nTPM]":"2.5","Tissue RNA - midbrain [nTPM]":"1.6","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"1.1","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"1.6","Tissue RNA - pons [nTPM]":"2.2","Tissue RNA - prostate [nTPM]":"1.1","Tissue RNA - rectum [nTPM]":"1.9","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"1.0","Tissue RNA - seminal vesicle [nTPM]":"2.8","Tissue RNA - skeletal muscle [nTPM]":"0.6","Tissue RNA - skin 1 [nTPM]":"2.0","Tissue RNA - small intestine [nTPM]":"2.3","Tissue RNA - smooth muscle [nTPM]":"1.6","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"15.6","Tissue RNA - stomach 1 [nTPM]":"1.5","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"1.8","Tissue RNA - thymus [nTPM]":"2.4","Tissue RNA - thyroid gland [nTPM]":"0.6","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"2.2","Tissue RNA - urinary bladder [nTPM]":"5.4","Tissue RNA - vagina [nTPM]":"0.9","Tissue RNA - white matter [nTPM]":"2.4","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"1.2","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"1.2","Cell RNA - BJ [nTPM]":"0.9","Cell RNA - BJ hTERT+ [nTPM]":"1.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.7","Cell RNA - GAMG [nTPM]":"2.3","Cell RNA - HaCaT [nTPM]":"1.9","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"11.8","Cell RNA - HeLa [nTPM]":"3.8","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.5","Cell RNA - HL-60 [nTPM]":"4.3","Cell RNA - HMC-1 [nTPM]":"18.3","Cell RNA - HSkMC [nTPM]":"0.9","Cell RNA - hTCEpi [nTPM]":"1.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.1","Cell RNA - hTERT-HME1 [nTPM]":"0.6","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"1.0","Cell RNA - K-562 [nTPM]":"2.7","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"1.3","Cell RNA - MCF7 [nTPM]":"0.5","Cell RNA - MOLT-4 [nTPM]":"1.5","Cell RNA - NB-4 [nTPM]":"11.5","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.8","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"1.5","Cell RNA - RPMI-8226 [nTPM]":"8.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"2.4","Cell RNA - SK-BR-3 [nTPM]":"2.0","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"5.4","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"1.1","Cell RNA - U-937 [nTPM]":"14.9","Cell RNA - WM-115 [nTPM]":"0.6","Blood RNA - basophil [nTPM]":"70.0","Blood RNA - classical monocyte [nTPM]":"13.9","Blood RNA - eosinophil [nTPM]":"74.7","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"46.9","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"9.3","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"55.7","Blood RNA - NK-cell [nTPM]":"3.3","Blood RNA - non-classical monocyte [nTPM]":"89.9","Blood RNA - plasmacytoid DC [nTPM]":"1.9","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"7.3","Brain RNA - amygdala [nTPM]":"1.0","Brain RNA - basal ganglia [nTPM]":"1.3","Brain RNA - cerebellum [nTPM]":"1.2","Brain RNA - cerebral cortex [nTPM]":"2.1","Brain RNA - hippocampal formation [nTPM]":"1.0","Brain RNA - hypothalamus [nTPM]":"1.5","Brain RNA - medulla oblongata [nTPM]":"2.5","Brain RNA - midbrain [nTPM]":"1.6","Brain RNA - pons [nTPM]":"2.2","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"1.8","Brain RNA - white matter [nTPM]":"2.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"1.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"12.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.5","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"1.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.9","Single Cell Type RNA - granulocytes [nTPM]":"47.9","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"69.4","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"73.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"49.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"2.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"3.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"3.0"},{"Gene":"ADGRG1","Gene synonym":["GPR56","TM7LN4","TM7XN1"],"Ensembl":"ENSG00000205336","Gene description":"Adhesion G protein-coupled receptor G1","Uniprot":["Q9Y653"],"Chromosome":"16","Position":"57610652-57665580","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion","Differentiation","Neurogenesis"],"Molecular function":["Developmental protein","G-protein coupled receptor","Heparin-binding","Receptor","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"thyroid gland":"216.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"222.5","Exocrine glandular cells":"170.7","NK-cells":"208.1","Syncytiotrophoblasts":"186.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"160.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"T-cells":"160.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"218.4","SK-BR-3":"277.7","SK-MEL-30":"297.8","TIME":"241.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046065"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"32000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046065":"AB_2679521"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.53e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.52e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Tissue RNA - adipose tissue [nTPM]":"50.9","Tissue RNA - adrenal gland [nTPM]":"13.2","Tissue RNA - amygdala [nTPM]":"79.6","Tissue RNA - appendix [nTPM]":"12.7","Tissue RNA - basal ganglia [nTPM]":"67.7","Tissue RNA - bone marrow [nTPM]":"19.6","Tissue RNA - breast [nTPM]":"50.5","Tissue RNA - cerebellum [nTPM]":"46.9","Tissue RNA - cerebral cortex [nTPM]":"115.2","Tissue RNA - cervix [nTPM]":"36.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"36.7","Tissue RNA - duodenum [nTPM]":"26.1","Tissue RNA - endometrium 1 [nTPM]":"19.7","Tissue RNA - epididymis [nTPM]":"84.2","Tissue RNA - esophagus [nTPM]":"46.7","Tissue RNA - fallopian tube [nTPM]":"52.2","Tissue RNA - gallbladder [nTPM]":"69.6","Tissue RNA - heart muscle [nTPM]":"36.8","Tissue RNA - hippocampal formation [nTPM]":"68.7","Tissue RNA - hypothalamus [nTPM]":"71.5","Tissue RNA - kidney [nTPM]":"158.9","Tissue RNA - liver [nTPM]":"4.2","Tissue RNA - lung [nTPM]":"37.3","Tissue RNA - lymph node [nTPM]":"5.2","Tissue RNA - medulla oblongata [nTPM]":"64.6","Tissue RNA - midbrain [nTPM]":"76.2","Tissue RNA - ovary [nTPM]":"5.3","Tissue RNA - pancreas [nTPM]":"59.8","Tissue RNA - parathyroid gland [nTPM]":"28.4","Tissue RNA - pituitary gland [nTPM]":"17.7","Tissue RNA - placenta [nTPM]":"101.3","Tissue RNA - pons [nTPM]":"73.9","Tissue RNA - prostate [nTPM]":"31.7","Tissue RNA - rectum [nTPM]":"33.4","Tissue RNA - retina [nTPM]":"6.6","Tissue RNA - salivary gland [nTPM]":"92.2","Tissue RNA - seminal vesicle [nTPM]":"57.5","Tissue RNA - skeletal muscle [nTPM]":"15.7","Tissue RNA - skin 1 [nTPM]":"87.5","Tissue RNA - small intestine [nTPM]":"19.3","Tissue RNA - smooth muscle [nTPM]":"19.8","Tissue RNA - spinal cord [nTPM]":"54.8","Tissue RNA - spleen [nTPM]":"12.3","Tissue RNA - stomach 1 [nTPM]":"47.9","Tissue RNA - testis [nTPM]":"45.4","Tissue RNA - thalamus [nTPM]":"92.5","Tissue RNA - thymus [nTPM]":"28.9","Tissue RNA - thyroid gland [nTPM]":"216.3","Tissue RNA - tongue [nTPM]":"16.9","Tissue RNA - tonsil [nTPM]":"15.6","Tissue RNA - urinary bladder [nTPM]":"37.1","Tissue RNA - vagina [nTPM]":"37.8","Tissue RNA - white matter [nTPM]":"51.6","Cell RNA - A-431 [nTPM]":"41.8","Cell RNA - A549 [nTPM]":"47.1","Cell RNA - AF22 [nTPM]":"12.0","Cell RNA - AN3-CA [nTPM]":"0.6","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"127.7","Cell RNA - BJ [nTPM]":"8.5","Cell RNA - BJ hTERT+ [nTPM]":"3.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.6","Cell RNA - CACO-2 [nTPM]":"34.7","Cell RNA - CAPAN-2 [nTPM]":"218.4","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"110.5","Cell RNA - fHDF\/TERT166 [nTPM]":"8.2","Cell RNA - GAMG [nTPM]":"196.1","Cell RNA - HaCaT [nTPM]":"149.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"103.4","Cell RNA - HBF TERT88 [nTPM]":"5.1","Cell RNA - HDLM-2 [nTPM]":"1.6","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"5.1","Cell RNA - HeLa [nTPM]":"56.0","Cell RNA - Hep G2 [nTPM]":"39.3","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"2.1","Cell RNA - HSkMC [nTPM]":"2.4","Cell RNA - hTCEpi [nTPM]":"143.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"24.5","Cell RNA - hTERT-HME1 [nTPM]":"10.2","Cell RNA - hTERT-RPE1 [nTPM]":"15.8","Cell RNA - HUVEC TERT2 [nTPM]":"118.1","Cell RNA - JURKAT [nTPM]":"1.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"1.2","Cell RNA - LHCN-M2 [nTPM]":"3.2","Cell RNA - MCF7 [nTPM]":"51.4","Cell RNA - MOLT-4 [nTPM]":"107.3","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"1.7","Cell RNA - OE19 [nTPM]":"143.3","Cell RNA - PC-3 [nTPM]":"42.6","Cell RNA - REH [nTPM]":"3.8","Cell RNA - RH-30 [nTPM]":"1.4","Cell RNA - RPMI-8226 [nTPM]":"30.8","Cell RNA - RPTEC TERT1 [nTPM]":"209.4","Cell RNA - RT4 [nTPM]":"134.9","Cell RNA - SCLC-21H [nTPM]":"38.2","Cell RNA - SH-SY5Y [nTPM]":"1.2","Cell RNA - SiHa [nTPM]":"2.0","Cell RNA - SK-BR-3 [nTPM]":"277.7","Cell RNA - SK-MEL-30 [nTPM]":"297.8","Cell RNA - SuSa [nTPM]":"8.4","Cell RNA - T-47d [nTPM]":"123.8","Cell RNA - THP-1 [nTPM]":"0.8","Cell RNA - TIME [nTPM]":"241.4","Cell RNA - U-138 MG [nTPM]":"25.6","Cell RNA - U-2 OS [nTPM]":"38.0","Cell RNA - U-2197 [nTPM]":"1.5","Cell RNA - U-251 MG [nTPM]":"96.2","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"2.1","Cell RNA - U-698 [nTPM]":"0.6","Cell RNA - U-87 MG [nTPM]":"200.5","Cell RNA - U-937 [nTPM]":"0.7","Cell RNA - WM-115 [nTPM]":"62.9","Blood RNA - basophil [nTPM]":"2.9","Blood RNA - classical monocyte [nTPM]":"0.8","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"160.3","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"1.9","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"10.5","Blood RNA - memory CD8 T-cell [nTPM]":"62.6","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"5.3","Blood RNA - naive CD8 T-cell [nTPM]":"45.2","Blood RNA - neutrophil [nTPM]":"3.3","Blood RNA - NK-cell [nTPM]":"30.6","Blood RNA - non-classical monocyte [nTPM]":"0.7","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"37.1","Brain RNA - amygdala [nTPM]":"79.6","Brain RNA - basal ganglia [nTPM]":"67.7","Brain RNA - cerebellum [nTPM]":"46.9","Brain RNA - cerebral cortex [nTPM]":"115.2","Brain RNA - hippocampal formation [nTPM]":"68.7","Brain RNA - hypothalamus [nTPM]":"71.5","Brain RNA - medulla oblongata [nTPM]":"64.6","Brain RNA - midbrain [nTPM]":"76.2","Brain RNA - pons [nTPM]":"73.9","Brain RNA - spinal cord [nTPM]":"54.8","Brain RNA - thalamus [nTPM]":"92.5","Brain RNA - white matter [nTPM]":"51.6","Single Cell Type RNA - Adipocytes [nTPM]":"107.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.9","Single Cell Type RNA - Astrocytes [nTPM]":"113.9","Single Cell Type RNA - B-cells [nTPM]":"3.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"0.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"27.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"21.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"79.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"222.5","Single Cell Type RNA - dendritic cells [nTPM]":"120.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"27.4","Single Cell Type RNA - Ductal cells [nTPM]":"33.9","Single Cell Type RNA - Early spermatids [nTPM]":"74.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"24.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.3","Single Cell Type RNA - Endothelial cells [nTPM]":"53.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.6","Single Cell Type RNA - Erythroid cells [nTPM]":"17.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"170.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"25.1","Single Cell Type RNA - Fibroblasts [nTPM]":"4.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"29.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"45.2","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"88.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"30.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.5","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"31.3","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"6.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"41.2","Single Cell Type RNA - monocytes [nTPM]":"1.1","Single Cell Type RNA - Muller glia cells [nTPM]":"4.8","Single Cell Type RNA - NK-cells [nTPM]":"208.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"85.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"101.1","Single Cell Type RNA - Paneth cells [nTPM]":"12.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"19.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"132.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.1","Single Cell Type RNA - Spermatocytes [nTPM]":"2.7","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"186.5","Single Cell Type RNA - T-cells [nTPM]":"35.1","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.6","Single Cell Type RNA - Urothelial cells [nTPM]":"19.5"},{"Gene":"ADGRG2","Gene synonym":["EDDM6","GPR64","HE6","TM7LN2"],"Ensembl":"ENSG00000173698","Gene description":"Adhesion G protein-coupled receptor G2","Uniprot":["Q8IZP9"],"Chromosome":"X","Position":"18989307-19122637","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"epididymis":"1227.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"7.2","Endometrial stromal cells":"5.4","Fibroblasts":"5.3","Gastric mucus-secreting cells":"9.2","Oligodendrocyte precursor cells":"10.1","Oligodendrocytes":"7.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"4.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"6.0","BEWO":"7.3","HeLa":"5.9","NTERA-2":"6.4","RPMI-8226":"4.5","SH-SY5Y":"6.6","U-2197":"14.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001478","HPA050029"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"22000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 30: Epididymis - Antimicrobial activity","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA001478":"AB_1078923","HPA050029":"AB_2680996"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.9","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.9","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"2.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"1.1","Tissue RNA - cervix [nTPM]":"1.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.5","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"1.0","Tissue RNA - epididymis [nTPM]":"1227.7","Tissue RNA - esophagus [nTPM]":"0.5","Tissue RNA - fallopian tube [nTPM]":"16.5","Tissue RNA - gallbladder [nTPM]":"1.6","Tissue RNA - heart muscle [nTPM]":"1.3","Tissue RNA - hippocampal formation [nTPM]":"0.8","Tissue RNA - hypothalamus [nTPM]":"0.7","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"0.7","Tissue RNA - lung [nTPM]":"1.3","Tissue RNA - lymph node [nTPM]":"5.0","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"1.5","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"1.2","Tissue RNA - parathyroid gland [nTPM]":"163.4","Tissue RNA - pituitary gland [nTPM]":"1.1","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"0.6","Tissue RNA - prostate [nTPM]":"2.1","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"0.9","Tissue RNA - salivary gland [nTPM]":"8.5","Tissue RNA - seminal vesicle [nTPM]":"3.6","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"1.1","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"2.4","Tissue RNA - stomach 1 [nTPM]":"9.0","Tissue RNA - testis [nTPM]":"1.9","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"6.6","Tissue RNA - thyroid gland [nTPM]":"1.6","Tissue RNA - tongue [nTPM]":"1.1","Tissue RNA - tonsil [nTPM]":"3.7","Tissue RNA - urinary bladder [nTPM]":"0.8","Tissue RNA - vagina [nTPM]":"1.0","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"6.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.9","Cell RNA - BEWO [nTPM]":"7.3","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"2.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"5.9","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.8","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"1.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"2.2","Cell RNA - NTERA-2 [nTPM]":"6.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"2.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"4.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"1.2","Cell RNA - SCLC-21H [nTPM]":"2.2","Cell RNA - SH-SY5Y [nTPM]":"6.6","Cell RNA - SiHa [nTPM]":"1.5","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.1","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"14.6","Cell RNA - U-251 MG [nTPM]":"2.5","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"1.1","Brain RNA - hippocampal formation [nTPM]":"0.8","Brain RNA - hypothalamus [nTPM]":"0.7","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"1.5","Brain RNA - pons [nTPM]":"0.6","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"3.6","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"5.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"1.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"ADGRG6","Gene synonym":["FLJ14937","GPR126"],"Ensembl":"ENSG00000112414","Gene description":"Adhesion G protein-coupled receptor G6","Uniprot":["Q86SQ4"],"Chromosome":"6","Position":"142301854-142446266","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"71.9","placenta":"47.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endothelial cells":"41.7","Hepatocytes":"143.8","Kupffer cells":"40.5","Pancreatic endocrine cells":"37.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"88.6","Hep G2":"84.8","hTERT-HME1":"81.5","HUVEC TERT2":"161.4","MCF7":"155.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017346"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017346":"AB_1849260"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.64e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.78e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.78e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.8","Tissue RNA - adrenal gland [nTPM]":"2.8","Tissue RNA - amygdala [nTPM]":"2.6","Tissue RNA - appendix [nTPM]":"4.1","Tissue RNA - basal ganglia [nTPM]":"2.3","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"5.2","Tissue RNA - cerebellum [nTPM]":"1.6","Tissue RNA - cerebral cortex [nTPM]":"1.9","Tissue RNA - cervix [nTPM]":"3.0","Tissue RNA - choroid plexus [nTPM]":"1.9","Tissue RNA - colon [nTPM]":"6.2","Tissue RNA - duodenum [nTPM]":"17.5","Tissue RNA - endometrium 1 [nTPM]":"1.1","Tissue RNA - epididymis [nTPM]":"1.3","Tissue RNA - esophagus [nTPM]":"11.6","Tissue RNA - fallopian tube [nTPM]":"5.2","Tissue RNA - gallbladder [nTPM]":"8.3","Tissue RNA - heart muscle [nTPM]":"4.0","Tissue RNA - hippocampal formation [nTPM]":"1.8","Tissue RNA - hypothalamus [nTPM]":"1.7","Tissue RNA - kidney [nTPM]":"7.2","Tissue RNA - liver [nTPM]":"71.9","Tissue RNA - lung [nTPM]":"15.2","Tissue RNA - lymph node [nTPM]":"1.7","Tissue RNA - medulla oblongata [nTPM]":"2.4","Tissue RNA - midbrain [nTPM]":"2.9","Tissue RNA - ovary [nTPM]":"1.4","Tissue RNA - pancreas [nTPM]":"3.2","Tissue RNA - parathyroid gland [nTPM]":"1.3","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"47.4","Tissue RNA - pons [nTPM]":"2.2","Tissue RNA - prostate [nTPM]":"3.2","Tissue RNA - rectum [nTPM]":"6.4","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"9.0","Tissue RNA - seminal vesicle [nTPM]":"6.5","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"14.5","Tissue RNA - small intestine [nTPM]":"10.2","Tissue RNA - smooth muscle [nTPM]":"2.2","Tissue RNA - spinal cord [nTPM]":"2.5","Tissue RNA - spleen [nTPM]":"7.5","Tissue RNA - stomach 1 [nTPM]":"12.3","Tissue RNA - testis [nTPM]":"2.1","Tissue RNA - thalamus [nTPM]":"4.6","Tissue RNA - thymus [nTPM]":"4.6","Tissue RNA - thyroid gland [nTPM]":"1.6","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"4.0","Tissue RNA - urinary bladder [nTPM]":"15.1","Tissue RNA - vagina [nTPM]":"5.6","Tissue RNA - white matter [nTPM]":"1.9","Cell RNA - A-431 [nTPM]":"17.0","Cell RNA - A549 [nTPM]":"88.6","Cell RNA - AF22 [nTPM]":"1.9","Cell RNA - AN3-CA [nTPM]":"9.4","Cell RNA - ASC diff [nTPM]":"0.5","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"23.1","Cell RNA - BJ hTERT+ [nTPM]":"4.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.7","Cell RNA - CACO-2 [nTPM]":"71.3","Cell RNA - CAPAN-2 [nTPM]":"51.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"20.3","Cell RNA - fHDF\/TERT166 [nTPM]":"13.4","Cell RNA - GAMG [nTPM]":"4.9","Cell RNA - HaCaT [nTPM]":"41.3","Cell RNA - HAP1 [nTPM]":"2.6","Cell RNA - HBEC3-KT [nTPM]":"22.1","Cell RNA - HBF TERT88 [nTPM]":"28.3","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"6.8","Cell RNA - HEL [nTPM]":"3.6","Cell RNA - HeLa [nTPM]":"14.5","Cell RNA - Hep G2 [nTPM]":"84.8","Cell RNA - HHSteC [nTPM]":"16.7","Cell RNA - HL-60 [nTPM]":"14.6","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"34.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.4","Cell RNA - hTERT-HME1 [nTPM]":"81.5","Cell RNA - hTERT-RPE1 [nTPM]":"10.0","Cell RNA - HUVEC TERT2 [nTPM]":"161.4","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"0.6","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"6.9","Cell RNA - MCF7 [nTPM]":"155.6","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.7","Cell RNA - OE19 [nTPM]":"6.2","Cell RNA - PC-3 [nTPM]":"20.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"7.7","Cell RNA - RPMI-8226 [nTPM]":"17.7","Cell RNA - RPTEC TERT1 [nTPM]":"9.0","Cell RNA - RT4 [nTPM]":"37.9","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"6.8","Cell RNA - SK-BR-3 [nTPM]":"30.8","Cell RNA - SK-MEL-30 [nTPM]":"14.5","Cell RNA - SuSa [nTPM]":"14.1","Cell RNA - T-47d [nTPM]":"16.7","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"5.6","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"7.6","Cell RNA - U-2197 [nTPM]":"7.7","Cell RNA - U-251 MG [nTPM]":"11.5","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"76.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.8","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.6","Brain RNA - basal ganglia [nTPM]":"2.3","Brain RNA - cerebellum [nTPM]":"1.6","Brain RNA - cerebral cortex [nTPM]":"1.9","Brain RNA - hippocampal formation [nTPM]":"1.8","Brain RNA - hypothalamus [nTPM]":"1.7","Brain RNA - medulla oblongata [nTPM]":"2.4","Brain RNA - midbrain [nTPM]":"2.9","Brain RNA - pons [nTPM]":"2.2","Brain RNA - spinal cord [nTPM]":"2.5","Brain RNA - thalamus [nTPM]":"4.6","Brain RNA - white matter [nTPM]":"1.9","Single Cell Type RNA - Adipocytes [nTPM]":"5.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"8.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"13.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"41.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"17.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"33.5","Single Cell Type RNA - Fibroblasts [nTPM]":"14.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"27.1","Single Cell Type RNA - Hepatocytes [nTPM]":"143.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"40.5","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"8.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"0.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"37.9","Single Cell Type RNA - Paneth cells [nTPM]":"8.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.3","Single Cell Type RNA - Spermatocytes [nTPM]":"2.6","Single Cell Type RNA - Spermatogonia [nTPM]":"5.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"30.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"13.5","Single Cell Type RNA - T-cells [nTPM]":"1.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.7","Single Cell Type RNA - Urothelial cells [nTPM]":"25.0"},{"Gene":"ADGRV1","Gene synonym":["DKFZp761P0710","FEB4","GPR98","KIAA0686","MASS1","USH2C","VLGR1"],"Ensembl":"ENSG00000164199","Gene description":"Adhesion G protein-coupled receptor V1","Uniprot":["Q8WXG9"],"Chromosome":"5","Position":"90529344-91164437","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["G-protein coupled receptor","Hydrolase","Receptor","Transducer"],"Disease involvement":["Deafness","Retinitis pigmentosa","Usher syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"adrenal gland":"533.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Astrocytes":"2207.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"15.5","HAP1":"23.0","K-562":"9.8","NTERA-2":"11.6","SCLC-21H":"11.1","SuSa":"15.0","U-266\/70":"13.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067503"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Lipid droplets"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":["Lipid droplets"],"Subcellular additional location":null,"Antibody RRID":{"HPA067503":"AB_2685856"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"533.0","Tissue RNA - amygdala [nTPM]":"36.9","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"47.8","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"3.6","Tissue RNA - cerebellum [nTPM]":"12.7","Tissue RNA - cerebral cortex [nTPM]":"40.3","Tissue RNA - cervix [nTPM]":"0.9","Tissue RNA - choroid plexus [nTPM]":"22.4","Tissue RNA - colon [nTPM]":"1.0","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.7","Tissue RNA - esophagus [nTPM]":"2.4","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"12.3","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"39.1","Tissue RNA - hypothalamus [nTPM]":"11.6","Tissue RNA - kidney [nTPM]":"21.5","Tissue RNA - liver [nTPM]":"42.3","Tissue RNA - lung [nTPM]":"2.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"9.4","Tissue RNA - midbrain [nTPM]":"12.8","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"1.5","Tissue RNA - parathyroid gland [nTPM]":"0.8","Tissue RNA - pituitary gland [nTPM]":"15.1","Tissue RNA - placenta [nTPM]":"4.1","Tissue RNA - pons [nTPM]":"9.4","Tissue RNA - prostate [nTPM]":"1.3","Tissue RNA - rectum [nTPM]":"1.0","Tissue RNA - retina [nTPM]":"18.2","Tissue RNA - salivary gland [nTPM]":"2.3","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"2.1","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"7.3","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"1.1","Tissue RNA - testis [nTPM]":"1.4","Tissue RNA - thalamus [nTPM]":"18.3","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"17.5","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"10.4","Tissue RNA - vagina [nTPM]":"1.9","Tissue RNA - white matter [nTPM]":"26.1","Cell RNA - A-431 [nTPM]":"0.5","Cell RNA - A549 [nTPM]":"2.1","Cell RNA - AF22 [nTPM]":"15.5","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"1.7","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"0.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"23.0","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"1.0","Cell RNA - HEK 293 [nTPM]":"4.3","Cell RNA - HEL [nTPM]":"4.1","Cell RNA - HeLa [nTPM]":"2.0","Cell RNA - Hep G2 [nTPM]":"1.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"4.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"9.8","Cell RNA - Karpas-707 [nTPM]":"2.6","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"2.1","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"11.6","Cell RNA - OE19 [nTPM]":"2.9","Cell RNA - PC-3 [nTPM]":"4.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"2.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"11.1","Cell RNA - SH-SY5Y [nTPM]":"2.7","Cell RNA - SiHa [nTPM]":"3.4","Cell RNA - SK-BR-3 [nTPM]":"2.2","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"15.0","Cell RNA - T-47d [nTPM]":"5.9","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.8","Cell RNA - U-138 MG [nTPM]":"0.4","Cell RNA - U-2 OS [nTPM]":"1.9","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"1.1","Cell RNA - U-266\/70 [nTPM]":"13.4","Cell RNA - U-266\/84 [nTPM]":"4.1","Cell RNA - U-698 [nTPM]":"0.6","Cell RNA - U-87 MG [nTPM]":"0.7","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"3.2","Blood RNA - classical monocyte [nTPM]":"0.9","Blood RNA - eosinophil [nTPM]":"2.8","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"1.7","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"2.9","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"4.6","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"1.6","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"36.9","Brain RNA - basal ganglia [nTPM]":"47.8","Brain RNA - cerebellum [nTPM]":"12.7","Brain RNA - cerebral cortex [nTPM]":"40.3","Brain RNA - hippocampal formation [nTPM]":"39.1","Brain RNA - hypothalamus [nTPM]":"11.6","Brain RNA - medulla oblongata [nTPM]":"9.4","Brain RNA - midbrain [nTPM]":"12.8","Brain RNA - pons [nTPM]":"9.4","Brain RNA - spinal cord [nTPM]":"7.3","Brain RNA - thalamus [nTPM]":"18.3","Brain RNA - white matter [nTPM]":"26.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.5","Single Cell Type RNA - Astrocytes [nTPM]":"2207.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"28.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"5.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"264.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.9","Single Cell Type RNA - Early spermatids [nTPM]":"43.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"1.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.3","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"54.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.6","Single Cell Type RNA - Fibroblasts [nTPM]":"1.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"6.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"12.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"54.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"51.5","Single Cell Type RNA - monocytes [nTPM]":"1.2","Single Cell Type RNA - Muller glia cells [nTPM]":"8.9","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"40.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.7","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"24.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"84.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"3.6","Single Cell Type RNA - Spermatogonia [nTPM]":"4.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.1","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.2","Single Cell Type RNA - Urothelial cells [nTPM]":"9.0"},{"Gene":"ADIPOQ","Gene synonym":["ACDC","ACRP30","adiponectin","apM1","GBP28"],"Ensembl":"ENSG00000181092","Gene description":"Adiponectin, C1Q and collagen domain containing","Uniprot":["Q15848"],"Chromosome":"3","Position":"186842704-186858463","Protein class":["Candidate cardiovascular disease genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted secreted proteins","Transporters"],"Biological process":null,"Molecular function":["Hormone"],"Disease involvement":["Diabetes mellitus","Disease variant","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"28","RNA tissue specific nTPM":{"adipose tissue":"898.8","breast":"248.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"1.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"breast cancer":"6.5","pancreatic cancer":"1.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"672","RNA cell line specific nTPM":{"ASC diff":"312.1"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB046467","HPA051767"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":8360000000,"Blood concentration - Conc. blood MS [pg\/L]":"910000000","Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB046467":"AB_1078104","HPA051767":"AB_2681598"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"898.8","Tissue RNA - adrenal gland [nTPM]":"8.9","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"2.4","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"248.9","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"7.7","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"1.2","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"7.6","Tissue RNA - heart muscle [nTPM]":"6.5","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.8","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"1.3","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"6.2","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"6.1","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"18.8","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"2.3","Tissue RNA - skin 1 [nTPM]":"6.6","Tissue RNA - small intestine [nTPM]":"8.5","Tissue RNA - smooth muscle [nTPM]":"1.2","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"3.9","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"2.2","Tissue RNA - thyroid gland [nTPM]":"2.9","Tissue RNA - tongue [nTPM]":"20.2","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"2.4","Tissue RNA - vagina [nTPM]":"0.9","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"312.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.4","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"ADK","Gene synonym":["AK"],"Ensembl":"ENSG00000156110","Gene description":"Adenosine kinase","Uniprot":["P55263"],"Chromosome":"10","Position":"74151202-74709963","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Purine salvage"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"151.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"245.3","Inhibitory neurons":"287.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB032876","HPA038391","HPA038409","HPA075222"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"920000","Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB032876":"AB_2242229","HPA038391":"AB_2675990","HPA038409":"AB_10675798","HPA075222":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.93e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.91e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Tissue RNA - adipose tissue [nTPM]":"23.9","Tissue RNA - adrenal gland [nTPM]":"15.5","Tissue RNA - amygdala [nTPM]":"13.0","Tissue RNA - appendix [nTPM]":"16.9","Tissue RNA - basal ganglia [nTPM]":"18.7","Tissue RNA - bone marrow [nTPM]":"28.6","Tissue RNA - breast [nTPM]":"27.4","Tissue RNA - cerebellum [nTPM]":"13.5","Tissue RNA - cerebral cortex [nTPM]":"17.7","Tissue RNA - cervix [nTPM]":"17.5","Tissue RNA - choroid plexus [nTPM]":"11.6","Tissue RNA - colon [nTPM]":"17.9","Tissue RNA - duodenum [nTPM]":"16.9","Tissue RNA - endometrium 1 [nTPM]":"10.8","Tissue RNA - epididymis [nTPM]":"16.5","Tissue RNA - esophagus [nTPM]":"47.3","Tissue RNA - fallopian tube [nTPM]":"16.5","Tissue RNA - gallbladder [nTPM]":"11.4","Tissue RNA - heart muscle [nTPM]":"27.2","Tissue RNA - hippocampal formation [nTPM]":"13.9","Tissue RNA - hypothalamus [nTPM]":"15.2","Tissue RNA - kidney [nTPM]":"35.8","Tissue RNA - liver [nTPM]":"151.2","Tissue RNA - lung [nTPM]":"24.4","Tissue RNA - lymph node [nTPM]":"22.8","Tissue RNA - medulla oblongata [nTPM]":"14.0","Tissue RNA - midbrain [nTPM]":"15.0","Tissue RNA - ovary [nTPM]":"8.3","Tissue RNA - pancreas [nTPM]":"18.8","Tissue RNA - parathyroid gland [nTPM]":"44.2","Tissue RNA - pituitary gland [nTPM]":"14.9","Tissue RNA - placenta [nTPM]":"26.6","Tissue RNA - pons [nTPM]":"16.5","Tissue RNA - prostate [nTPM]":"14.9","Tissue RNA - rectum [nTPM]":"19.5","Tissue RNA - retina [nTPM]":"16.1","Tissue RNA - salivary gland [nTPM]":"20.0","Tissue RNA - seminal vesicle [nTPM]":"16.0","Tissue RNA - skeletal muscle [nTPM]":"41.5","Tissue RNA - skin 1 [nTPM]":"33.9","Tissue RNA - small intestine [nTPM]":"12.4","Tissue RNA - smooth muscle [nTPM]":"14.8","Tissue RNA - spinal cord [nTPM]":"14.2","Tissue RNA - spleen [nTPM]":"15.0","Tissue RNA - stomach 1 [nTPM]":"12.1","Tissue RNA - testis [nTPM]":"15.5","Tissue RNA - thalamus [nTPM]":"14.1","Tissue RNA - thymus [nTPM]":"27.0","Tissue RNA - thyroid gland [nTPM]":"38.2","Tissue RNA - tongue [nTPM]":"47.1","Tissue RNA - tonsil [nTPM]":"34.5","Tissue RNA - urinary bladder [nTPM]":"24.5","Tissue RNA - vagina [nTPM]":"24.7","Tissue RNA - white matter [nTPM]":"15.8","Cell RNA - A-431 [nTPM]":"177.3","Cell RNA - A549 [nTPM]":"37.4","Cell RNA - AF22 [nTPM]":"37.2","Cell RNA - AN3-CA [nTPM]":"50.5","Cell RNA - ASC diff [nTPM]":"37.1","Cell RNA - ASC TERT1 [nTPM]":"54.7","Cell RNA - BEWO [nTPM]":"88.2","Cell RNA - BJ [nTPM]":"140.8","Cell RNA - BJ hTERT+ [nTPM]":"105.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"103.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"114.5","Cell RNA - CACO-2 [nTPM]":"114.0","Cell RNA - CAPAN-2 [nTPM]":"172.6","Cell RNA - Daudi [nTPM]":"86.3","Cell RNA - EFO-21 [nTPM]":"34.2","Cell RNA - fHDF\/TERT166 [nTPM]":"57.7","Cell RNA - GAMG [nTPM]":"51.3","Cell RNA - HaCaT [nTPM]":"151.1","Cell RNA - HAP1 [nTPM]":"44.1","Cell RNA - HBEC3-KT [nTPM]":"150.1","Cell RNA - HBF TERT88 [nTPM]":"167.0","Cell RNA - HDLM-2 [nTPM]":"59.1","Cell RNA - HEK 293 [nTPM]":"51.3","Cell RNA - HEL [nTPM]":"55.6","Cell RNA - HeLa [nTPM]":"59.8","Cell RNA - Hep G2 [nTPM]":"122.8","Cell RNA - HHSteC [nTPM]":"41.7","Cell RNA - HL-60 [nTPM]":"87.6","Cell RNA - HMC-1 [nTPM]":"22.5","Cell RNA - HSkMC [nTPM]":"51.1","Cell RNA - hTCEpi [nTPM]":"95.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"77.4","Cell RNA - hTERT-HME1 [nTPM]":"191.7","Cell RNA - hTERT-RPE1 [nTPM]":"79.0","Cell RNA - HUVEC TERT2 [nTPM]":"91.2","Cell RNA - JURKAT [nTPM]":"38.7","Cell RNA - K-562 [nTPM]":"41.8","Cell RNA - Karpas-707 [nTPM]":"28.4","Cell RNA - LHCN-M2 [nTPM]":"78.8","Cell RNA - MCF7 [nTPM]":"101.7","Cell RNA - MOLT-4 [nTPM]":"102.5","Cell RNA - NB-4 [nTPM]":"129.0","Cell RNA - NTERA-2 [nTPM]":"9.9","Cell RNA - OE19 [nTPM]":"80.0","Cell RNA - PC-3 [nTPM]":"276.3","Cell RNA - REH [nTPM]":"100.6","Cell RNA - RH-30 [nTPM]":"63.7","Cell RNA - RPMI-8226 [nTPM]":"69.4","Cell RNA - RPTEC TERT1 [nTPM]":"117.1","Cell RNA - RT4 [nTPM]":"92.7","Cell RNA - SCLC-21H [nTPM]":"29.5","Cell RNA - SH-SY5Y [nTPM]":"33.8","Cell RNA - SiHa [nTPM]":"63.6","Cell RNA - SK-BR-3 [nTPM]":"239.7","Cell RNA - SK-MEL-30 [nTPM]":"49.5","Cell RNA - SuSa [nTPM]":"34.7","Cell RNA - T-47d [nTPM]":"159.7","Cell RNA - THP-1 [nTPM]":"69.3","Cell RNA - TIME [nTPM]":"82.8","Cell RNA - U-138 MG [nTPM]":"34.3","Cell RNA - U-2 OS [nTPM]":"67.0","Cell RNA - U-2197 [nTPM]":"93.2","Cell RNA - U-251 MG [nTPM]":"123.0","Cell RNA - U-266\/70 [nTPM]":"40.5","Cell RNA - U-266\/84 [nTPM]":"48.3","Cell RNA - U-698 [nTPM]":"98.1","Cell RNA - U-87 MG [nTPM]":"65.0","Cell RNA - U-937 [nTPM]":"127.6","Cell RNA - WM-115 [nTPM]":"22.1","Blood RNA - basophil [nTPM]":"2.3","Blood RNA - classical monocyte [nTPM]":"34.2","Blood RNA - eosinophil [nTPM]":"4.1","Blood RNA - gdT-cell [nTPM]":"12.9","Blood RNA - intermediate monocyte [nTPM]":"65.5","Blood RNA - MAIT T-cell [nTPM]":"29.9","Blood RNA - memory B-cell [nTPM]":"103.7","Blood RNA - memory CD4 T-cell [nTPM]":"28.2","Blood RNA - memory CD8 T-cell [nTPM]":"24.1","Blood RNA - myeloid DC [nTPM]":"83.1","Blood RNA - naive B-cell [nTPM]":"155.0","Blood RNA - naive CD4 T-cell [nTPM]":"21.3","Blood RNA - naive CD8 T-cell [nTPM]":"19.2","Blood RNA - neutrophil [nTPM]":"11.1","Blood RNA - NK-cell [nTPM]":"20.7","Blood RNA - non-classical monocyte [nTPM]":"80.4","Blood RNA - plasmacytoid DC [nTPM]":"57.6","Blood RNA - T-reg [nTPM]":"55.7","Blood RNA - total PBMC [nTPM]":"36.3","Brain RNA - amygdala [nTPM]":"13.0","Brain RNA - basal ganglia [nTPM]":"18.7","Brain RNA - cerebellum [nTPM]":"13.5","Brain RNA - cerebral cortex [nTPM]":"17.7","Brain RNA - hippocampal formation [nTPM]":"13.9","Brain RNA - hypothalamus [nTPM]":"15.2","Brain RNA - medulla oblongata [nTPM]":"14.0","Brain RNA - midbrain [nTPM]":"15.0","Brain RNA - pons [nTPM]":"16.5","Brain RNA - spinal cord [nTPM]":"14.2","Brain RNA - thalamus [nTPM]":"14.1","Brain RNA - white matter [nTPM]":"15.8","Single Cell Type RNA - Adipocytes [nTPM]":"9.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"83.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"75.8","Single Cell Type RNA - Astrocytes [nTPM]":"136.5","Single Cell Type RNA - B-cells [nTPM]":"84.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"94.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"73.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"102.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"105.9","Single Cell Type RNA - Bipolar cells [nTPM]":"16.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"26.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"67.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"72.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"56.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"136.7","Single Cell Type RNA - dendritic cells [nTPM]":"25.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"92.0","Single Cell Type RNA - Ductal cells [nTPM]":"83.2","Single Cell Type RNA - Early spermatids [nTPM]":"80.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"40.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.8","Single Cell Type RNA - Endothelial cells [nTPM]":"14.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.8","Single Cell Type RNA - Erythroid cells [nTPM]":"27.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"245.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"67.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"139.5","Single Cell Type RNA - Fibroblasts [nTPM]":"27.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"55.6","Single Cell Type RNA - granulocytes [nTPM]":"21.5","Single Cell Type RNA - Granulosa cells [nTPM]":"9.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.2","Single Cell Type RNA - Hepatocytes [nTPM]":"130.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"39.3","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"287.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.1","Single Cell Type RNA - Ionocytes [nTPM]":"44.7","Single Cell Type RNA - Kupffer cells [nTPM]":"25.2","Single Cell Type RNA - Langerhans cells [nTPM]":"50.0","Single Cell Type RNA - Late spermatids [nTPM]":"26.9","Single Cell Type RNA - Leydig cells [nTPM]":"16.8","Single Cell Type RNA - Macrophages [nTPM]":"33.7","Single Cell Type RNA - Melanocytes [nTPM]":"48.0","Single Cell Type RNA - Microglial cells [nTPM]":"198.6","Single Cell Type RNA - monocytes [nTPM]":"44.1","Single Cell Type RNA - Muller glia cells [nTPM]":"14.1","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"140.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"165.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"62.7","Single Cell Type RNA - Paneth cells [nTPM]":"10.4","Single Cell Type RNA - Peritubular cells [nTPM]":"12.0","Single Cell Type RNA - Plasma cells [nTPM]":"39.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"92.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"64.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.0","Single Cell Type RNA - Spermatocytes [nTPM]":"17.4","Single Cell Type RNA - Spermatogonia [nTPM]":"14.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"96.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"97.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"107.3","Single Cell Type RNA - T-cells [nTPM]":"32.7","Single Cell Type RNA - Theca cells [nTPM]":"17.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.5","Single Cell Type RNA - Urothelial cells [nTPM]":"66.3"},{"Gene":"ADPRS","Gene synonym":["ADPRHL2","ARH3","FLJ20446"],"Ensembl":"ENSG00000116863","Gene description":"ADP-ribosylserine hydrolase","Uniprot":["Q9NX46"],"Chromosome":"1","Position":"36088892-36093932","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Cytotrophoblasts":"79.2","Extravillous trophoblasts":"40.7","Hofbauer cells":"51.6","Syncytiotrophoblasts":"70.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026641","HPA027104","HPA027141"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"54000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA026641":null,"HPA027104":"AB_10601330","HPA027141":"AB_1844619"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.10e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.71e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-2"},"Tissue RNA - adipose tissue [nTPM]":"19.0","Tissue RNA - adrenal gland [nTPM]":"36.7","Tissue RNA - amygdala [nTPM]":"28.4","Tissue RNA - appendix [nTPM]":"16.0","Tissue RNA - basal ganglia [nTPM]":"30.0","Tissue RNA - bone marrow [nTPM]":"19.7","Tissue RNA - breast [nTPM]":"18.5","Tissue RNA - cerebellum [nTPM]":"31.3","Tissue RNA - cerebral cortex [nTPM]":"30.3","Tissue RNA - cervix [nTPM]":"20.7","Tissue RNA - choroid plexus [nTPM]":"33.4","Tissue RNA - colon [nTPM]":"19.6","Tissue RNA - duodenum [nTPM]":"15.6","Tissue RNA - endometrium 1 [nTPM]":"17.6","Tissue RNA - epididymis [nTPM]":"15.0","Tissue RNA - esophagus [nTPM]":"36.1","Tissue RNA - fallopian tube [nTPM]":"33.5","Tissue RNA - gallbladder [nTPM]":"13.3","Tissue RNA - heart muscle [nTPM]":"20.7","Tissue RNA - hippocampal formation [nTPM]":"28.6","Tissue RNA - hypothalamus [nTPM]":"29.1","Tissue RNA - kidney [nTPM]":"27.7","Tissue RNA - liver [nTPM]":"22.4","Tissue RNA - lung [nTPM]":"20.6","Tissue RNA - lymph node [nTPM]":"21.5","Tissue RNA - medulla oblongata [nTPM]":"32.5","Tissue RNA - midbrain [nTPM]":"29.7","Tissue RNA - ovary [nTPM]":"19.7","Tissue RNA - pancreas [nTPM]":"17.9","Tissue RNA - parathyroid gland [nTPM]":"17.6","Tissue RNA - pituitary gland [nTPM]":"17.7","Tissue RNA - placenta [nTPM]":"20.8","Tissue RNA - pons [nTPM]":"31.2","Tissue RNA - prostate [nTPM]":"19.9","Tissue RNA - rectum [nTPM]":"12.4","Tissue RNA - retina [nTPM]":"9.1","Tissue RNA - salivary gland [nTPM]":"20.9","Tissue RNA - seminal vesicle [nTPM]":"16.3","Tissue RNA - skeletal muscle [nTPM]":"34.4","Tissue RNA - skin 1 [nTPM]":"34.1","Tissue RNA - small intestine [nTPM]":"16.8","Tissue RNA - smooth muscle [nTPM]":"16.4","Tissue RNA - spinal cord [nTPM]":"31.9","Tissue RNA - spleen [nTPM]":"23.1","Tissue RNA - stomach 1 [nTPM]":"17.6","Tissue RNA - testis [nTPM]":"28.7","Tissue RNA - thalamus [nTPM]":"29.7","Tissue RNA - thymus [nTPM]":"20.9","Tissue RNA - thyroid gland [nTPM]":"19.4","Tissue RNA - tongue [nTPM]":"21.8","Tissue RNA - tonsil [nTPM]":"20.2","Tissue RNA - urinary bladder [nTPM]":"21.3","Tissue RNA - vagina [nTPM]":"22.2","Tissue RNA - white matter [nTPM]":"33.9","Cell RNA - A-431 [nTPM]":"54.3","Cell RNA - A549 [nTPM]":"22.4","Cell RNA - AF22 [nTPM]":"26.2","Cell RNA - AN3-CA [nTPM]":"37.2","Cell RNA - ASC diff [nTPM]":"23.6","Cell RNA - ASC TERT1 [nTPM]":"17.1","Cell RNA - BEWO [nTPM]":"37.3","Cell RNA - BJ [nTPM]":"39.4","Cell RNA - BJ hTERT+ [nTPM]":"32.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"62.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"60.9","Cell RNA - CACO-2 [nTPM]":"26.8","Cell RNA - CAPAN-2 [nTPM]":"47.7","Cell RNA - Daudi [nTPM]":"38.4","Cell RNA - EFO-21 [nTPM]":"37.5","Cell RNA - fHDF\/TERT166 [nTPM]":"39.5","Cell RNA - GAMG [nTPM]":"32.0","Cell RNA - HaCaT [nTPM]":"32.9","Cell RNA - HAP1 [nTPM]":"33.4","Cell RNA - HBEC3-KT [nTPM]":"60.5","Cell RNA - HBF TERT88 [nTPM]":"37.0","Cell RNA - HDLM-2 [nTPM]":"27.7","Cell RNA - HEK 293 [nTPM]":"41.8","Cell RNA - HEL [nTPM]":"34.9","Cell RNA - HeLa [nTPM]":"27.0","Cell RNA - Hep G2 [nTPM]":"36.3","Cell RNA - HHSteC [nTPM]":"44.4","Cell RNA - HL-60 [nTPM]":"40.2","Cell RNA - HMC-1 [nTPM]":"19.9","Cell RNA - HSkMC [nTPM]":"20.3","Cell RNA - hTCEpi [nTPM]":"45.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"56.5","Cell RNA - hTERT-HME1 [nTPM]":"24.5","Cell RNA - hTERT-RPE1 [nTPM]":"47.2","Cell RNA - HUVEC TERT2 [nTPM]":"39.9","Cell RNA - JURKAT [nTPM]":"36.2","Cell RNA - K-562 [nTPM]":"30.8","Cell RNA - Karpas-707 [nTPM]":"30.9","Cell RNA - LHCN-M2 [nTPM]":"29.6","Cell RNA - MCF7 [nTPM]":"26.0","Cell RNA - MOLT-4 [nTPM]":"40.9","Cell RNA - NB-4 [nTPM]":"60.5","Cell RNA - NTERA-2 [nTPM]":"56.5","Cell RNA - OE19 [nTPM]":"31.8","Cell RNA - PC-3 [nTPM]":"46.0","Cell RNA - REH [nTPM]":"32.9","Cell RNA - RH-30 [nTPM]":"27.6","Cell RNA - RPMI-8226 [nTPM]":"38.8","Cell RNA - RPTEC TERT1 [nTPM]":"56.5","Cell RNA - RT4 [nTPM]":"43.8","Cell RNA - SCLC-21H [nTPM]":"32.1","Cell RNA - SH-SY5Y [nTPM]":"50.8","Cell RNA - SiHa [nTPM]":"28.9","Cell RNA - SK-BR-3 [nTPM]":"29.9","Cell RNA - SK-MEL-30 [nTPM]":"65.9","Cell RNA - SuSa [nTPM]":"34.4","Cell RNA - T-47d [nTPM]":"30.9","Cell RNA - THP-1 [nTPM]":"34.3","Cell RNA - TIME [nTPM]":"27.6","Cell RNA - U-138 MG [nTPM]":"35.7","Cell RNA - U-2 OS [nTPM]":"37.0","Cell RNA - U-2197 [nTPM]":"50.1","Cell RNA - U-251 MG [nTPM]":"53.0","Cell RNA - U-266\/70 [nTPM]":"39.8","Cell RNA - U-266\/84 [nTPM]":"41.2","Cell RNA - U-698 [nTPM]":"34.2","Cell RNA - U-87 MG [nTPM]":"51.7","Cell RNA - U-937 [nTPM]":"39.6","Cell RNA - WM-115 [nTPM]":"22.4","Blood RNA - basophil [nTPM]":"40.6","Blood RNA - classical monocyte [nTPM]":"58.3","Blood RNA - eosinophil [nTPM]":"65.8","Blood RNA - gdT-cell [nTPM]":"43.4","Blood RNA - intermediate monocyte [nTPM]":"74.1","Blood RNA - MAIT T-cell [nTPM]":"41.5","Blood RNA - memory B-cell [nTPM]":"43.5","Blood RNA - memory CD4 T-cell [nTPM]":"47.6","Blood RNA - memory CD8 T-cell [nTPM]":"50.8","Blood RNA - myeloid DC [nTPM]":"71.4","Blood RNA - naive B-cell [nTPM]":"51.5","Blood RNA - naive CD4 T-cell [nTPM]":"47.7","Blood RNA - naive CD8 T-cell [nTPM]":"40.3","Blood RNA - neutrophil [nTPM]":"57.1","Blood RNA - NK-cell [nTPM]":"47.9","Blood RNA - non-classical monocyte [nTPM]":"77.7","Blood RNA - plasmacytoid DC [nTPM]":"44.8","Blood RNA - T-reg [nTPM]":"43.4","Blood RNA - total PBMC [nTPM]":"57.8","Brain RNA - amygdala [nTPM]":"28.4","Brain RNA - basal ganglia [nTPM]":"30.0","Brain RNA - cerebellum [nTPM]":"31.3","Brain RNA - cerebral cortex [nTPM]":"30.3","Brain RNA - hippocampal formation [nTPM]":"28.6","Brain RNA - hypothalamus [nTPM]":"29.1","Brain RNA - medulla oblongata [nTPM]":"32.5","Brain RNA - midbrain [nTPM]":"29.7","Brain RNA - pons [nTPM]":"31.2","Brain RNA - spinal cord [nTPM]":"31.9","Brain RNA - thalamus [nTPM]":"29.7","Brain RNA - white matter [nTPM]":"33.9","Single Cell Type RNA - Adipocytes [nTPM]":"3.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"79.2","Single Cell Type RNA - dendritic cells [nTPM]":"6.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"2.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"40.7","Single Cell Type RNA - Fibroblasts [nTPM]":"6.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"51.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"70.6","Single Cell Type RNA - T-cells [nTPM]":"1.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"ADSL","Gene synonym":[],"Ensembl":"ENSG00000239900","Gene description":"Adenylosuccinate lyase","Uniprot":["P30566"],"Chromosome":"22","Position":"40346461-40390463","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Purine biosynthesis"],"Molecular function":["Lyase"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"skeletal muscle":"345.1","tongue":"242.3"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000525","CAB019285"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"440000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB019285":null,"HPA000525":"AB_1078106"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.38e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.81e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Tissue RNA - adipose tissue [nTPM]":"29.8","Tissue RNA - adrenal gland [nTPM]":"33.9","Tissue RNA - amygdala [nTPM]":"10.6","Tissue RNA - appendix [nTPM]":"31.1","Tissue RNA - basal ganglia [nTPM]":"11.2","Tissue RNA - bone marrow [nTPM]":"40.6","Tissue RNA - breast [nTPM]":"33.1","Tissue RNA - cerebellum [nTPM]":"12.5","Tissue RNA - cerebral cortex [nTPM]":"13.3","Tissue RNA - cervix [nTPM]":"30.7","Tissue RNA - choroid plexus [nTPM]":"12.9","Tissue RNA - colon [nTPM]":"36.5","Tissue RNA - duodenum [nTPM]":"22.7","Tissue RNA - endometrium 1 [nTPM]":"34.9","Tissue RNA - epididymis [nTPM]":"21.9","Tissue RNA - esophagus [nTPM]":"29.8","Tissue RNA - fallopian tube [nTPM]":"33.5","Tissue RNA - gallbladder [nTPM]":"20.6","Tissue RNA - heart muscle [nTPM]":"47.4","Tissue RNA - hippocampal formation [nTPM]":"10.9","Tissue RNA - hypothalamus [nTPM]":"10.6","Tissue RNA - kidney [nTPM]":"33.6","Tissue RNA - liver [nTPM]":"32.1","Tissue RNA - lung [nTPM]":"22.7","Tissue RNA - lymph node [nTPM]":"46.9","Tissue RNA - medulla oblongata [nTPM]":"10.5","Tissue RNA - midbrain [nTPM]":"11.7","Tissue RNA - ovary [nTPM]":"33.5","Tissue RNA - pancreas [nTPM]":"45.2","Tissue RNA - parathyroid gland [nTPM]":"29.3","Tissue RNA - pituitary gland [nTPM]":"22.0","Tissue RNA - placenta [nTPM]":"30.2","Tissue RNA - pons [nTPM]":"10.9","Tissue RNA - prostate [nTPM]":"23.8","Tissue RNA - rectum [nTPM]":"35.4","Tissue RNA - retina [nTPM]":"10.3","Tissue RNA - salivary gland [nTPM]":"25.7","Tissue RNA - seminal vesicle [nTPM]":"22.3","Tissue RNA - skeletal muscle [nTPM]":"345.1","Tissue RNA - skin 1 [nTPM]":"22.2","Tissue RNA - small intestine [nTPM]":"28.8","Tissue RNA - smooth muscle [nTPM]":"41.1","Tissue RNA - spinal cord [nTPM]":"10.0","Tissue RNA - spleen [nTPM]":"33.5","Tissue RNA - stomach 1 [nTPM]":"28.0","Tissue RNA - testis [nTPM]":"29.2","Tissue RNA - thalamus [nTPM]":"10.5","Tissue RNA - thymus [nTPM]":"50.5","Tissue RNA - thyroid gland [nTPM]":"29.6","Tissue RNA - tongue [nTPM]":"242.3","Tissue RNA - tonsil [nTPM]":"48.5","Tissue RNA - urinary bladder [nTPM]":"36.0","Tissue RNA - vagina [nTPM]":"25.2","Tissue RNA - white matter [nTPM]":"10.8","Cell RNA - A-431 [nTPM]":"98.0","Cell RNA - A549 [nTPM]":"110.2","Cell RNA - AF22 [nTPM]":"88.3","Cell RNA - AN3-CA [nTPM]":"124.9","Cell RNA - ASC diff [nTPM]":"62.6","Cell RNA - ASC TERT1 [nTPM]":"89.5","Cell RNA - BEWO [nTPM]":"106.5","Cell RNA - BJ [nTPM]":"82.0","Cell RNA - BJ hTERT+ [nTPM]":"85.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"187.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"138.1","Cell RNA - CACO-2 [nTPM]":"189.0","Cell RNA - CAPAN-2 [nTPM]":"51.9","Cell RNA - Daudi [nTPM]":"279.0","Cell RNA - EFO-21 [nTPM]":"73.2","Cell RNA - fHDF\/TERT166 [nTPM]":"102.3","Cell RNA - GAMG [nTPM]":"84.9","Cell RNA - HaCaT [nTPM]":"67.3","Cell RNA - HAP1 [nTPM]":"203.5","Cell RNA - HBEC3-KT [nTPM]":"137.4","Cell RNA - HBF TERT88 [nTPM]":"187.7","Cell RNA - HDLM-2 [nTPM]":"75.3","Cell RNA - HEK 293 [nTPM]":"197.5","Cell RNA - HEL [nTPM]":"126.5","Cell RNA - HeLa [nTPM]":"98.4","Cell RNA - Hep G2 [nTPM]":"166.5","Cell RNA - HHSteC [nTPM]":"134.6","Cell RNA - HL-60 [nTPM]":"423.0","Cell RNA - HMC-1 [nTPM]":"96.3","Cell RNA - HSkMC [nTPM]":"97.7","Cell RNA - hTCEpi [nTPM]":"76.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"161.5","Cell RNA - hTERT-HME1 [nTPM]":"169.8","Cell RNA - hTERT-RPE1 [nTPM]":"91.3","Cell RNA - HUVEC TERT2 [nTPM]":"138.9","Cell RNA - JURKAT [nTPM]":"127.3","Cell RNA - K-562 [nTPM]":"153.1","Cell RNA - Karpas-707 [nTPM]":"114.3","Cell RNA - LHCN-M2 [nTPM]":"136.4","Cell RNA - MCF7 [nTPM]":"105.0","Cell RNA - MOLT-4 [nTPM]":"130.2","Cell RNA - NB-4 [nTPM]":"131.2","Cell RNA - NTERA-2 [nTPM]":"152.5","Cell RNA - OE19 [nTPM]":"121.3","Cell RNA - PC-3 [nTPM]":"119.3","Cell RNA - REH [nTPM]":"195.1","Cell RNA - RH-30 [nTPM]":"203.6","Cell RNA - RPMI-8226 [nTPM]":"198.2","Cell RNA - RPTEC TERT1 [nTPM]":"118.9","Cell RNA - RT4 [nTPM]":"67.8","Cell RNA - SCLC-21H [nTPM]":"58.8","Cell RNA - SH-SY5Y [nTPM]":"54.4","Cell RNA - SiHa [nTPM]":"106.2","Cell RNA - SK-BR-3 [nTPM]":"54.1","Cell RNA - SK-MEL-30 [nTPM]":"170.7","Cell RNA - SuSa [nTPM]":"78.5","Cell RNA - T-47d [nTPM]":"76.8","Cell RNA - THP-1 [nTPM]":"134.7","Cell RNA - TIME [nTPM]":"91.2","Cell RNA - U-138 MG [nTPM]":"93.3","Cell RNA - U-2 OS [nTPM]":"173.7","Cell RNA - U-2197 [nTPM]":"85.3","Cell RNA - U-251 MG [nTPM]":"168.8","Cell RNA - U-266\/70 [nTPM]":"109.0","Cell RNA - U-266\/84 [nTPM]":"212.6","Cell RNA - U-698 [nTPM]":"218.2","Cell RNA - U-87 MG [nTPM]":"80.9","Cell RNA - U-937 [nTPM]":"149.5","Cell RNA - WM-115 [nTPM]":"97.7","Blood RNA - basophil [nTPM]":"29.0","Blood RNA - classical monocyte [nTPM]":"47.2","Blood RNA - eosinophil [nTPM]":"19.9","Blood RNA - gdT-cell [nTPM]":"35.5","Blood RNA - intermediate monocyte [nTPM]":"55.2","Blood RNA - MAIT T-cell [nTPM]":"49.5","Blood RNA - memory B-cell [nTPM]":"34.6","Blood RNA - memory CD4 T-cell [nTPM]":"76.1","Blood RNA - memory CD8 T-cell [nTPM]":"48.5","Blood RNA - myeloid DC [nTPM]":"68.1","Blood RNA - naive B-cell [nTPM]":"33.5","Blood RNA - naive CD4 T-cell [nTPM]":"58.3","Blood RNA - naive CD8 T-cell [nTPM]":"45.0","Blood RNA - neutrophil [nTPM]":"4.1","Blood RNA - NK-cell [nTPM]":"48.2","Blood RNA - non-classical monocyte [nTPM]":"49.7","Blood RNA - plasmacytoid DC [nTPM]":"34.4","Blood RNA - T-reg [nTPM]":"81.7","Blood RNA - total PBMC [nTPM]":"62.3","Brain RNA - amygdala [nTPM]":"10.6","Brain RNA - basal ganglia [nTPM]":"11.2","Brain RNA - cerebellum [nTPM]":"12.5","Brain RNA - cerebral cortex [nTPM]":"13.3","Brain RNA - hippocampal formation [nTPM]":"10.9","Brain RNA - hypothalamus [nTPM]":"10.6","Brain RNA - medulla oblongata [nTPM]":"10.5","Brain RNA - midbrain [nTPM]":"11.7","Brain RNA - pons [nTPM]":"10.9","Brain RNA - spinal cord [nTPM]":"10.0","Brain RNA - thalamus [nTPM]":"10.5","Brain RNA - white matter [nTPM]":"10.8","Single Cell Type RNA - Adipocytes [nTPM]":"10.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.8","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"28.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"48.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.9","Single Cell Type RNA - Bipolar cells [nTPM]":"16.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"30.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"20.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"85.3","Single Cell Type RNA - dendritic cells [nTPM]":"15.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"61.3","Single Cell Type RNA - Early spermatids [nTPM]":"44.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.2","Single Cell Type RNA - Endothelial cells [nTPM]":"21.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.8","Single Cell Type RNA - Erythroid cells [nTPM]":"54.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"43.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"78.9","Single Cell Type RNA - Fibroblasts [nTPM]":"21.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.6","Single Cell Type RNA - granulocytes [nTPM]":"36.8","Single Cell Type RNA - Granulosa cells [nTPM]":"8.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.9","Single Cell Type RNA - Hepatocytes [nTPM]":"25.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"60.3","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.1","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"44.8","Single Cell Type RNA - Langerhans cells [nTPM]":"26.7","Single Cell Type RNA - Late spermatids [nTPM]":"25.2","Single Cell Type RNA - Leydig cells [nTPM]":"24.8","Single Cell Type RNA - Macrophages [nTPM]":"22.7","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"41.9","Single Cell Type RNA - Muller glia cells [nTPM]":"45.1","Single Cell Type RNA - NK-cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"33.7","Single Cell Type RNA - Paneth cells [nTPM]":"15.6","Single Cell Type RNA - Peritubular cells [nTPM]":"14.3","Single Cell Type RNA - Plasma cells [nTPM]":"52.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"21.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"21.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.1","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"38.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.8","Single Cell Type RNA - Spermatocytes [nTPM]":"61.2","Single Cell Type RNA - Spermatogonia [nTPM]":"82.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"35.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"33.1","Single Cell Type RNA - T-cells [nTPM]":"32.2","Single Cell Type RNA - Theca cells [nTPM]":"8.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"37.7","Single Cell Type RNA - Urothelial cells [nTPM]":"14.1"},{"Gene":"ADSS1","Gene synonym":["ADSSL1","FLJ38602"],"Ensembl":"ENSG00000185100","Gene description":"Adenylosuccinate synthase 1","Uniprot":["Q8N142"],"Chromosome":"14","Position":"104724229-104747325","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Purine biosynthesis"],"Molecular function":["Ligase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"skeletal muscle":"1273.1","tongue":"609.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"20","RNA single cell type specific nTPM":{"Cardiomyocytes":"137.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"15.2","MCF7":"14.2","OE19":"23.2","SiHa":"23.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052621"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"290000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052621":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.99e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.1","Tissue RNA - adrenal gland [nTPM]":"5.1","Tissue RNA - amygdala [nTPM]":"3.8","Tissue RNA - appendix [nTPM]":"1.0","Tissue RNA - basal ganglia [nTPM]":"6.8","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"4.4","Tissue RNA - cerebellum [nTPM]":"6.6","Tissue RNA - cerebral cortex [nTPM]":"5.6","Tissue RNA - cervix [nTPM]":"4.1","Tissue RNA - choroid plexus [nTPM]":"7.6","Tissue RNA - colon [nTPM]":"3.0","Tissue RNA - duodenum [nTPM]":"2.7","Tissue RNA - endometrium 1 [nTPM]":"3.3","Tissue RNA - epididymis [nTPM]":"4.5","Tissue RNA - esophagus [nTPM]":"18.5","Tissue RNA - fallopian tube [nTPM]":"6.5","Tissue RNA - gallbladder [nTPM]":"5.7","Tissue RNA - heart muscle [nTPM]":"100.2","Tissue RNA - hippocampal formation [nTPM]":"3.7","Tissue RNA - hypothalamus [nTPM]":"6.7","Tissue RNA - kidney [nTPM]":"14.8","Tissue RNA - liver [nTPM]":"28.8","Tissue RNA - lung [nTPM]":"3.1","Tissue RNA - lymph node [nTPM]":"1.1","Tissue RNA - medulla oblongata [nTPM]":"6.0","Tissue RNA - midbrain [nTPM]":"6.0","Tissue RNA - ovary [nTPM]":"2.7","Tissue RNA - pancreas [nTPM]":"7.9","Tissue RNA - parathyroid gland [nTPM]":"7.3","Tissue RNA - pituitary gland [nTPM]":"10.0","Tissue RNA - placenta [nTPM]":"7.3","Tissue RNA - pons [nTPM]":"6.1","Tissue RNA - prostate [nTPM]":"7.6","Tissue RNA - rectum [nTPM]":"1.4","Tissue RNA - retina [nTPM]":"10.1","Tissue RNA - salivary gland [nTPM]":"10.7","Tissue RNA - seminal vesicle [nTPM]":"4.0","Tissue RNA - skeletal muscle [nTPM]":"1273.1","Tissue RNA - skin 1 [nTPM]":"5.5","Tissue RNA - small intestine [nTPM]":"2.8","Tissue RNA - smooth muscle [nTPM]":"2.3","Tissue RNA - spinal cord [nTPM]":"5.2","Tissue RNA - spleen [nTPM]":"2.0","Tissue RNA - stomach 1 [nTPM]":"6.5","Tissue RNA - testis [nTPM]":"18.5","Tissue RNA - thalamus [nTPM]":"5.5","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"7.4","Tissue RNA - tongue [nTPM]":"609.8","Tissue RNA - tonsil [nTPM]":"0.8","Tissue RNA - urinary bladder [nTPM]":"6.5","Tissue RNA - vagina [nTPM]":"5.4","Tissue RNA - white matter [nTPM]":"7.7","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"3.2","Cell RNA - AF22 [nTPM]":"2.4","Cell RNA - AN3-CA [nTPM]":"7.1","Cell RNA - ASC diff [nTPM]":"1.7","Cell RNA - ASC TERT1 [nTPM]":"1.1","Cell RNA - BEWO [nTPM]":"0.8","Cell RNA - BJ [nTPM]":"0.9","Cell RNA - BJ hTERT+ [nTPM]":"1.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.7","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"2.5","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"15.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.8","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"1.3","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.5","Cell RNA - HBF TERT88 [nTPM]":"0.6","Cell RNA - HDLM-2 [nTPM]":"1.0","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"7.9","Cell RNA - Hep G2 [nTPM]":"1.1","Cell RNA - HHSteC [nTPM]":"1.8","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"6.0","Cell RNA - HSkMC [nTPM]":"3.2","Cell RNA - hTCEpi [nTPM]":"2.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"2.6","Cell RNA - hTERT-RPE1 [nTPM]":"2.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.4","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"2.9","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"1.2","Cell RNA - MCF7 [nTPM]":"14.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.7","Cell RNA - NTERA-2 [nTPM]":"2.1","Cell RNA - OE19 [nTPM]":"23.2","Cell RNA - PC-3 [nTPM]":"1.3","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.9","Cell RNA - RPTEC TERT1 [nTPM]":"0.5","Cell RNA - RT4 [nTPM]":"1.7","Cell RNA - SCLC-21H [nTPM]":"2.0","Cell RNA - SH-SY5Y [nTPM]":"4.2","Cell RNA - SiHa [nTPM]":"23.1","Cell RNA - SK-BR-3 [nTPM]":"1.0","Cell RNA - SK-MEL-30 [nTPM]":"3.3","Cell RNA - SuSa [nTPM]":"1.8","Cell RNA - T-47d [nTPM]":"7.1","Cell RNA - THP-1 [nTPM]":"2.1","Cell RNA - TIME [nTPM]":"0.8","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.6","Cell RNA - U-2197 [nTPM]":"1.6","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"4.4","Cell RNA - U-266\/84 [nTPM]":"3.5","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"2.2","Cell RNA - U-937 [nTPM]":"1.0","Cell RNA - WM-115 [nTPM]":"1.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.8","Brain RNA - basal ganglia [nTPM]":"6.8","Brain RNA - cerebellum [nTPM]":"6.6","Brain RNA - cerebral cortex [nTPM]":"5.6","Brain RNA - hippocampal formation [nTPM]":"3.7","Brain RNA - hypothalamus [nTPM]":"6.7","Brain RNA - medulla oblongata [nTPM]":"6.0","Brain RNA - midbrain [nTPM]":"6.0","Brain RNA - pons [nTPM]":"6.1","Brain RNA - spinal cord [nTPM]":"5.2","Brain RNA - thalamus [nTPM]":"5.5","Brain RNA - white matter [nTPM]":"7.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"137.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.9","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.7","Single Cell Type RNA - Fibroblasts [nTPM]":"6.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"AEBP1","Gene synonym":["ACLP"],"Ensembl":"ENSG00000106624","Gene description":"AE binding protein 1","Uniprot":["Q8IUX7"],"Chromosome":"7","Position":"44104345-44114562","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Calmodulin-binding","DNA-binding","Repressor"],"Disease involvement":["Disease variant","Ehlers-Danlos syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"103.0","Fibroblasts":"263.2","Leydig cells":"151.6","Peritubular cells":"508.9","Smooth muscle cells":"173.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"plasmacytoid DC":"7.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"7.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"141.1","BJ":"193.0","BJ hTERT+":"126.0","fHDF\/TERT166":"208.9","JURKAT":"145.0","WM-115":"117.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"57.6"},"Antibody":["CAB009966","HPA047724","HPA063595","HPA064970"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2700000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"CAB009966":"AB_2225690","HPA047724":"AB_2680132","HPA063595":"AB_2685052","HPA064970":"AB_2685394"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.60e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.79e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.31e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-3"},"Tissue RNA - adipose tissue [nTPM]":"190.5","Tissue RNA - adrenal gland [nTPM]":"59.9","Tissue RNA - amygdala [nTPM]":"45.0","Tissue RNA - appendix [nTPM]":"59.8","Tissue RNA - basal ganglia [nTPM]":"56.0","Tissue RNA - bone marrow [nTPM]":"10.6","Tissue RNA - breast [nTPM]":"153.0","Tissue RNA - cerebellum [nTPM]":"38.6","Tissue RNA - cerebral cortex [nTPM]":"44.8","Tissue RNA - cervix [nTPM]":"312.1","Tissue RNA - choroid plexus [nTPM]":"28.0","Tissue RNA - colon [nTPM]":"95.3","Tissue RNA - duodenum [nTPM]":"19.2","Tissue RNA - endometrium 1 [nTPM]":"268.8","Tissue RNA - epididymis [nTPM]":"59.6","Tissue RNA - esophagus [nTPM]":"65.7","Tissue RNA - fallopian tube [nTPM]":"199.8","Tissue RNA - gallbladder [nTPM]":"155.9","Tissue RNA - heart muscle [nTPM]":"156.7","Tissue RNA - hippocampal formation [nTPM]":"47.3","Tissue RNA - hypothalamus [nTPM]":"92.9","Tissue RNA - kidney [nTPM]":"68.7","Tissue RNA - liver [nTPM]":"20.3","Tissue RNA - lung [nTPM]":"166.0","Tissue RNA - lymph node [nTPM]":"45.5","Tissue RNA - medulla oblongata [nTPM]":"114.7","Tissue RNA - midbrain [nTPM]":"81.5","Tissue RNA - ovary [nTPM]":"253.7","Tissue RNA - pancreas [nTPM]":"28.9","Tissue RNA - parathyroid gland [nTPM]":"10.1","Tissue RNA - pituitary gland [nTPM]":"43.3","Tissue RNA - placenta [nTPM]":"89.0","Tissue RNA - pons [nTPM]":"79.6","Tissue RNA - prostate [nTPM]":"112.1","Tissue RNA - rectum [nTPM]":"25.0","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"50.7","Tissue RNA - seminal vesicle [nTPM]":"213.5","Tissue RNA - skeletal muscle [nTPM]":"21.3","Tissue RNA - skin 1 [nTPM]":"84.8","Tissue RNA - small intestine [nTPM]":"79.1","Tissue RNA - smooth muscle [nTPM]":"119.3","Tissue RNA - spinal cord [nTPM]":"74.3","Tissue RNA - spleen [nTPM]":"54.4","Tissue RNA - stomach 1 [nTPM]":"71.2","Tissue RNA - testis [nTPM]":"40.4","Tissue RNA - thalamus [nTPM]":"52.1","Tissue RNA - thymus [nTPM]":"73.3","Tissue RNA - thyroid gland [nTPM]":"83.7","Tissue RNA - tongue [nTPM]":"14.1","Tissue RNA - tonsil [nTPM]":"16.7","Tissue RNA - urinary bladder [nTPM]":"138.7","Tissue RNA - vagina [nTPM]":"198.0","Tissue RNA - white matter [nTPM]":"66.6","Cell RNA - A-431 [nTPM]":"0.6","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"44.5","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"141.1","Cell RNA - ASC TERT1 [nTPM]":"49.6","Cell RNA - BEWO [nTPM]":"1.0","Cell RNA - BJ [nTPM]":"193.0","Cell RNA - BJ hTERT+ [nTPM]":"126.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.5","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"5.3","Cell RNA - EFO-21 [nTPM]":"20.9","Cell RNA - fHDF\/TERT166 [nTPM]":"208.9","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"2.4","Cell RNA - HBEC3-KT [nTPM]":"3.5","Cell RNA - HBF TERT88 [nTPM]":"9.1","Cell RNA - HDLM-2 [nTPM]":"0.6","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"13.3","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"39.6","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"75.8","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"72.9","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"1.1","Cell RNA - HUVEC TERT2 [nTPM]":"9.7","Cell RNA - JURKAT [nTPM]":"145.0","Cell RNA - K-562 [nTPM]":"8.3","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"86.9","Cell RNA - NB-4 [nTPM]":"16.1","Cell RNA - NTERA-2 [nTPM]":"19.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"71.3","Cell RNA - RH-30 [nTPM]":"1.7","Cell RNA - RPMI-8226 [nTPM]":"1.7","Cell RNA - RPTEC TERT1 [nTPM]":"5.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"4.9","Cell RNA - SH-SY5Y [nTPM]":"25.3","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"85.9","Cell RNA - SuSa [nTPM]":"41.9","Cell RNA - T-47d [nTPM]":"0.4","Cell RNA - THP-1 [nTPM]":"14.4","Cell RNA - TIME [nTPM]":"34.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"86.2","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"1.0","Cell RNA - U-266\/84 [nTPM]":"0.9","Cell RNA - U-698 [nTPM]":"102.8","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"117.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"1.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.9","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"7.6","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"45.0","Brain RNA - basal ganglia [nTPM]":"56.0","Brain RNA - cerebellum [nTPM]":"38.6","Brain RNA - cerebral cortex [nTPM]":"44.8","Brain RNA - hippocampal formation [nTPM]":"47.3","Brain RNA - hypothalamus [nTPM]":"92.9","Brain RNA - medulla oblongata [nTPM]":"114.7","Brain RNA - midbrain [nTPM]":"81.5","Brain RNA - pons [nTPM]":"79.6","Brain RNA - spinal cord [nTPM]":"74.3","Brain RNA - thalamus [nTPM]":"52.1","Brain RNA - white matter [nTPM]":"66.6","Single Cell Type RNA - Adipocytes [nTPM]":"23.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.5","Single Cell Type RNA - Astrocytes [nTPM]":"32.3","Single Cell Type RNA - B-cells [nTPM]":"11.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"34.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"26.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"1.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.0","Single Cell Type RNA - dendritic cells [nTPM]":"22.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.9","Single Cell Type RNA - Early spermatids [nTPM]":"3.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"103.0","Single Cell Type RNA - Endothelial cells [nTPM]":"18.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.3","Single Cell Type RNA - Fibroblasts [nTPM]":"263.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.9","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"33.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"30.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.8","Single Cell Type RNA - Langerhans cells [nTPM]":"42.0","Single Cell Type RNA - Late spermatids [nTPM]":"18.0","Single Cell Type RNA - Leydig cells [nTPM]":"151.6","Single Cell Type RNA - Macrophages [nTPM]":"3.2","Single Cell Type RNA - Melanocytes [nTPM]":"85.4","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"508.9","Single Cell Type RNA - Plasma cells [nTPM]":"9.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"173.4","Single Cell Type RNA - Spermatocytes [nTPM]":"4.0","Single Cell Type RNA - Spermatogonia [nTPM]":"4.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - T-cells [nTPM]":"4.8","Single Cell Type RNA - Theca cells [nTPM]":"28.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"2.4"},{"Gene":"AFG3L2","Gene synonym":["SCA28","SPAX5"],"Ensembl":"ENSG00000141385","Gene description":"AFG3 like matrix AAA peptidase subunit 2","Uniprot":["Q9Y4W6"],"Chromosome":"18","Position":"12328944-12377227","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004479","HPA004480"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA004479":"AB_1078109","HPA004480":"AB_1078108"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.68e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.05e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Tissue RNA - adipose tissue [nTPM]":"26.1","Tissue RNA - adrenal gland [nTPM]":"25.9","Tissue RNA - amygdala [nTPM]":"16.4","Tissue RNA - appendix [nTPM]":"21.9","Tissue RNA - basal ganglia [nTPM]":"17.0","Tissue RNA - bone marrow [nTPM]":"32.4","Tissue RNA - breast [nTPM]":"29.2","Tissue RNA - cerebellum [nTPM]":"18.2","Tissue RNA - cerebral cortex [nTPM]":"19.0","Tissue RNA - cervix [nTPM]":"24.1","Tissue RNA - choroid plexus [nTPM]":"30.8","Tissue RNA - colon [nTPM]":"60.8","Tissue RNA - duodenum [nTPM]":"79.9","Tissue RNA - endometrium 1 [nTPM]":"22.1","Tissue RNA - epididymis [nTPM]":"17.5","Tissue RNA - esophagus [nTPM]":"41.5","Tissue RNA - fallopian tube [nTPM]":"23.8","Tissue RNA - gallbladder [nTPM]":"18.3","Tissue RNA - heart muscle [nTPM]":"88.0","Tissue RNA - hippocampal formation [nTPM]":"17.0","Tissue RNA - hypothalamus [nTPM]":"18.7","Tissue RNA - kidney [nTPM]":"62.7","Tissue RNA - liver [nTPM]":"51.0","Tissue RNA - lung [nTPM]":"21.8","Tissue RNA - lymph node [nTPM]":"23.7","Tissue RNA - medulla oblongata [nTPM]":"17.7","Tissue RNA - midbrain [nTPM]":"16.6","Tissue RNA - ovary [nTPM]":"24.1","Tissue RNA - pancreas [nTPM]":"41.1","Tissue RNA - parathyroid gland [nTPM]":"76.0","Tissue RNA - pituitary gland [nTPM]":"18.6","Tissue RNA - placenta [nTPM]":"23.5","Tissue RNA - pons [nTPM]":"18.8","Tissue RNA - prostate [nTPM]":"24.6","Tissue RNA - rectum [nTPM]":"54.1","Tissue RNA - retina [nTPM]":"20.3","Tissue RNA - salivary gland [nTPM]":"30.8","Tissue RNA - seminal vesicle [nTPM]":"24.4","Tissue RNA - skeletal muscle [nTPM]":"145.4","Tissue RNA - skin 1 [nTPM]":"29.8","Tissue RNA - small intestine [nTPM]":"58.7","Tissue RNA - smooth muscle [nTPM]":"25.4","Tissue RNA - spinal cord [nTPM]":"15.8","Tissue RNA - spleen [nTPM]":"18.5","Tissue RNA - stomach 1 [nTPM]":"39.1","Tissue RNA - testis [nTPM]":"18.5","Tissue RNA - thalamus [nTPM]":"19.0","Tissue RNA - thymus [nTPM]":"24.3","Tissue RNA - thyroid gland [nTPM]":"39.2","Tissue RNA - tongue [nTPM]":"155.8","Tissue RNA - tonsil [nTPM]":"31.0","Tissue RNA - urinary bladder [nTPM]":"30.9","Tissue RNA - vagina [nTPM]":"19.6","Tissue RNA - white matter [nTPM]":"17.6","Cell RNA - A-431 [nTPM]":"56.5","Cell RNA - A549 [nTPM]":"56.6","Cell RNA - AF22 [nTPM]":"39.7","Cell RNA - AN3-CA [nTPM]":"44.8","Cell RNA - ASC diff [nTPM]":"45.2","Cell RNA - ASC TERT1 [nTPM]":"48.6","Cell RNA - BEWO [nTPM]":"52.7","Cell RNA - BJ [nTPM]":"61.9","Cell RNA - BJ hTERT+ [nTPM]":"61.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"86.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"63.1","Cell RNA - CACO-2 [nTPM]":"88.1","Cell RNA - CAPAN-2 [nTPM]":"34.1","Cell RNA - Daudi [nTPM]":"161.3","Cell RNA - EFO-21 [nTPM]":"66.3","Cell RNA - fHDF\/TERT166 [nTPM]":"56.6","Cell RNA - GAMG [nTPM]":"76.8","Cell RNA - HaCaT [nTPM]":"55.6","Cell RNA - HAP1 [nTPM]":"101.4","Cell RNA - HBEC3-KT [nTPM]":"71.3","Cell RNA - HBF TERT88 [nTPM]":"70.3","Cell RNA - HDLM-2 [nTPM]":"38.1","Cell RNA - HEK 293 [nTPM]":"43.5","Cell RNA - HEL [nTPM]":"48.5","Cell RNA - HeLa [nTPM]":"59.3","Cell RNA - Hep G2 [nTPM]":"83.5","Cell RNA - HHSteC [nTPM]":"61.1","Cell RNA - HL-60 [nTPM]":"185.0","Cell RNA - HMC-1 [nTPM]":"69.8","Cell RNA - HSkMC [nTPM]":"54.3","Cell RNA - hTCEpi [nTPM]":"76.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"82.1","Cell RNA - hTERT-HME1 [nTPM]":"107.7","Cell RNA - hTERT-RPE1 [nTPM]":"47.8","Cell RNA - HUVEC TERT2 [nTPM]":"64.0","Cell RNA - JURKAT [nTPM]":"57.0","Cell RNA - K-562 [nTPM]":"111.3","Cell RNA - Karpas-707 [nTPM]":"92.8","Cell RNA - LHCN-M2 [nTPM]":"43.6","Cell RNA - MCF7 [nTPM]":"89.0","Cell RNA - MOLT-4 [nTPM]":"66.7","Cell RNA - NB-4 [nTPM]":"58.5","Cell RNA - NTERA-2 [nTPM]":"55.3","Cell RNA - OE19 [nTPM]":"277.4","Cell RNA - PC-3 [nTPM]":"41.9","Cell RNA - REH [nTPM]":"74.0","Cell RNA - RH-30 [nTPM]":"125.1","Cell RNA - RPMI-8226 [nTPM]":"135.2","Cell RNA - RPTEC TERT1 [nTPM]":"74.9","Cell RNA - RT4 [nTPM]":"123.6","Cell RNA - SCLC-21H [nTPM]":"73.7","Cell RNA - SH-SY5Y [nTPM]":"51.3","Cell RNA - SiHa [nTPM]":"97.0","Cell RNA - SK-BR-3 [nTPM]":"103.8","Cell RNA - SK-MEL-30 [nTPM]":"90.0","Cell RNA - SuSa [nTPM]":"50.5","Cell RNA - T-47d [nTPM]":"47.8","Cell RNA - THP-1 [nTPM]":"84.5","Cell RNA - TIME [nTPM]":"49.0","Cell RNA - U-138 MG [nTPM]":"102.4","Cell RNA - U-2 OS [nTPM]":"88.6","Cell RNA - U-2197 [nTPM]":"98.7","Cell RNA - U-251 MG [nTPM]":"81.7","Cell RNA - U-266\/70 [nTPM]":"64.7","Cell RNA - U-266\/84 [nTPM]":"80.7","Cell RNA - U-698 [nTPM]":"104.1","Cell RNA - U-87 MG [nTPM]":"56.2","Cell RNA - U-937 [nTPM]":"71.4","Cell RNA - WM-115 [nTPM]":"48.0","Blood RNA - basophil [nTPM]":"3.8","Blood RNA - classical monocyte [nTPM]":"16.5","Blood RNA - eosinophil [nTPM]":"12.4","Blood RNA - gdT-cell [nTPM]":"11.6","Blood RNA - intermediate monocyte [nTPM]":"17.6","Blood RNA - MAIT T-cell [nTPM]":"13.9","Blood RNA - memory B-cell [nTPM]":"14.0","Blood RNA - memory CD4 T-cell [nTPM]":"13.8","Blood RNA - memory CD8 T-cell [nTPM]":"17.9","Blood RNA - myeloid DC [nTPM]":"21.8","Blood RNA - naive B-cell [nTPM]":"10.3","Blood RNA - naive CD4 T-cell [nTPM]":"17.2","Blood RNA - naive CD8 T-cell [nTPM]":"20.2","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"28.4","Blood RNA - non-classical monocyte [nTPM]":"16.2","Blood RNA - plasmacytoid DC [nTPM]":"11.5","Blood RNA - T-reg [nTPM]":"9.5","Blood RNA - total PBMC [nTPM]":"13.4","Brain RNA - amygdala [nTPM]":"16.4","Brain RNA - basal ganglia [nTPM]":"17.0","Brain RNA - cerebellum [nTPM]":"18.2","Brain RNA - cerebral cortex [nTPM]":"19.0","Brain RNA - hippocampal formation [nTPM]":"17.0","Brain RNA - hypothalamus [nTPM]":"18.7","Brain RNA - medulla oblongata [nTPM]":"17.7","Brain RNA - midbrain [nTPM]":"16.6","Brain RNA - pons [nTPM]":"18.8","Brain RNA - spinal cord [nTPM]":"15.8","Brain RNA - thalamus [nTPM]":"19.0","Brain RNA - white matter [nTPM]":"17.6","Single Cell Type RNA - Adipocytes [nTPM]":"24.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"49.2","Single Cell Type RNA - Astrocytes [nTPM]":"23.2","Single Cell Type RNA - B-cells [nTPM]":"36.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"22.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"45.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"42.7","Single Cell Type RNA - Bipolar cells [nTPM]":"50.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"36.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"36.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"74.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"50.1","Single Cell Type RNA - Club cells [nTPM]":"28.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"35.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"50.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"58.5","Single Cell Type RNA - dendritic cells [nTPM]":"29.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"85.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"72.4","Single Cell Type RNA - Ductal cells [nTPM]":"39.5","Single Cell Type RNA - Early spermatids [nTPM]":"5.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"37.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"52.3","Single Cell Type RNA - Endothelial cells [nTPM]":"27.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"39.1","Single Cell Type RNA - Erythroid cells [nTPM]":"61.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"21.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"37.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"37.9","Single Cell Type RNA - Fibroblasts [nTPM]":"31.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"53.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"46.1","Single Cell Type RNA - granulocytes [nTPM]":"14.5","Single Cell Type RNA - Granulosa cells [nTPM]":"41.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.8","Single Cell Type RNA - Hepatocytes [nTPM]":"85.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"37.0","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"26.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"82.6","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"32.6","Single Cell Type RNA - Langerhans cells [nTPM]":"14.4","Single Cell Type RNA - Late spermatids [nTPM]":"5.5","Single Cell Type RNA - Leydig cells [nTPM]":"32.9","Single Cell Type RNA - Macrophages [nTPM]":"34.2","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"27.6","Single Cell Type RNA - Muller glia cells [nTPM]":"26.9","Single Cell Type RNA - NK-cells [nTPM]":"40.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"47.8","Single Cell Type RNA - Paneth cells [nTPM]":"43.1","Single Cell Type RNA - Peritubular cells [nTPM]":"30.1","Single Cell Type RNA - Plasma cells [nTPM]":"38.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"43.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"88.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"100.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"58.3","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"53.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.9","Single Cell Type RNA - Spermatocytes [nTPM]":"50.9","Single Cell Type RNA - Spermatogonia [nTPM]":"65.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"75.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"31.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"92.8","Single Cell Type RNA - T-cells [nTPM]":"28.4","Single Cell Type RNA - Theca cells [nTPM]":"60.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"94.9","Single Cell Type RNA - Urothelial cells [nTPM]":"38.2"},{"Gene":"AGA","Gene synonym":["ASRG"],"Ensembl":"ENSG00000038002","Gene description":"Aspartylglucosaminidase","Uniprot":["P20933"],"Chromosome":"4","Position":"177430774-177442437","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+":"77.5","Karpas-707":"111.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031415","HPA031417"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"36000000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 30: Epididymis - Antimicrobial activity","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031415":"AB_10603578","HPA031417":"AB_10670967"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.61e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.99e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.4","Tissue RNA - adrenal gland [nTPM]":"13.3","Tissue RNA - amygdala [nTPM]":"8.1","Tissue RNA - appendix [nTPM]":"9.1","Tissue RNA - basal ganglia [nTPM]":"10.4","Tissue RNA - bone marrow [nTPM]":"15.4","Tissue RNA - breast [nTPM]":"21.1","Tissue RNA - cerebellum [nTPM]":"9.8","Tissue RNA - cerebral cortex [nTPM]":"12.0","Tissue RNA - cervix [nTPM]":"9.2","Tissue RNA - choroid plexus [nTPM]":"16.2","Tissue RNA - colon [nTPM]":"13.1","Tissue RNA - duodenum [nTPM]":"9.6","Tissue RNA - endometrium 1 [nTPM]":"8.6","Tissue RNA - epididymis [nTPM]":"30.2","Tissue RNA - esophagus [nTPM]":"15.9","Tissue RNA - fallopian tube [nTPM]":"8.4","Tissue RNA - gallbladder [nTPM]":"13.1","Tissue RNA - heart muscle [nTPM]":"7.5","Tissue RNA - hippocampal formation [nTPM]":"8.4","Tissue RNA - hypothalamus [nTPM]":"9.9","Tissue RNA - kidney [nTPM]":"15.3","Tissue RNA - liver [nTPM]":"18.7","Tissue RNA - lung [nTPM]":"11.6","Tissue RNA - lymph node [nTPM]":"12.2","Tissue RNA - medulla oblongata [nTPM]":"11.4","Tissue RNA - midbrain [nTPM]":"9.1","Tissue RNA - ovary [nTPM]":"10.2","Tissue RNA - pancreas [nTPM]":"15.1","Tissue RNA - parathyroid gland [nTPM]":"17.1","Tissue RNA - pituitary gland [nTPM]":"6.1","Tissue RNA - placenta [nTPM]":"8.4","Tissue RNA - pons [nTPM]":"11.4","Tissue RNA - prostate [nTPM]":"11.8","Tissue RNA - rectum [nTPM]":"13.1","Tissue RNA - retina [nTPM]":"6.6","Tissue RNA - salivary gland [nTPM]":"14.9","Tissue RNA - seminal vesicle [nTPM]":"9.8","Tissue RNA - skeletal muscle [nTPM]":"9.0","Tissue RNA - skin 1 [nTPM]":"20.6","Tissue RNA - small intestine [nTPM]":"12.4","Tissue RNA - smooth muscle [nTPM]":"9.5","Tissue RNA - spinal cord [nTPM]":"9.5","Tissue RNA - spleen [nTPM]":"10.3","Tissue RNA - stomach 1 [nTPM]":"16.2","Tissue RNA - testis [nTPM]":"13.2","Tissue RNA - thalamus [nTPM]":"8.6","Tissue RNA - thymus [nTPM]":"11.1","Tissue RNA - thyroid gland [nTPM]":"15.8","Tissue RNA - tongue [nTPM]":"5.8","Tissue RNA - tonsil [nTPM]":"15.6","Tissue RNA - urinary bladder [nTPM]":"10.9","Tissue RNA - vagina [nTPM]":"8.2","Tissue RNA - white matter [nTPM]":"13.7","Cell RNA - A-431 [nTPM]":"5.4","Cell RNA - A549 [nTPM]":"11.9","Cell RNA - AF22 [nTPM]":"13.3","Cell RNA - AN3-CA [nTPM]":"18.8","Cell RNA - ASC diff [nTPM]":"14.9","Cell RNA - ASC TERT1 [nTPM]":"13.2","Cell RNA - BEWO [nTPM]":"9.0","Cell RNA - BJ [nTPM]":"39.5","Cell RNA - BJ hTERT+ [nTPM]":"77.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.8","Cell RNA - CACO-2 [nTPM]":"6.2","Cell RNA - CAPAN-2 [nTPM]":"26.2","Cell RNA - Daudi [nTPM]":"26.9","Cell RNA - EFO-21 [nTPM]":"7.2","Cell RNA - fHDF\/TERT166 [nTPM]":"30.0","Cell RNA - GAMG [nTPM]":"9.7","Cell RNA - HaCaT [nTPM]":"6.5","Cell RNA - HAP1 [nTPM]":"11.3","Cell RNA - HBEC3-KT [nTPM]":"13.0","Cell RNA - HBF TERT88 [nTPM]":"39.4","Cell RNA - HDLM-2 [nTPM]":"17.3","Cell RNA - HEK 293 [nTPM]":"7.5","Cell RNA - HEL [nTPM]":"11.2","Cell RNA - HeLa [nTPM]":"11.9","Cell RNA - Hep G2 [nTPM]":"17.3","Cell RNA - HHSteC [nTPM]":"10.0","Cell RNA - HL-60 [nTPM]":"19.6","Cell RNA - HMC-1 [nTPM]":"7.4","Cell RNA - HSkMC [nTPM]":"9.6","Cell RNA - hTCEpi [nTPM]":"22.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.7","Cell RNA - hTERT-HME1 [nTPM]":"6.5","Cell RNA - hTERT-RPE1 [nTPM]":"18.0","Cell RNA - HUVEC TERT2 [nTPM]":"18.7","Cell RNA - JURKAT [nTPM]":"11.4","Cell RNA - K-562 [nTPM]":"10.3","Cell RNA - Karpas-707 [nTPM]":"111.6","Cell RNA - LHCN-M2 [nTPM]":"8.0","Cell RNA - MCF7 [nTPM]":"14.6","Cell RNA - MOLT-4 [nTPM]":"15.9","Cell RNA - NB-4 [nTPM]":"12.0","Cell RNA - NTERA-2 [nTPM]":"5.2","Cell RNA - OE19 [nTPM]":"10.5","Cell RNA - PC-3 [nTPM]":"12.2","Cell RNA - REH [nTPM]":"5.0","Cell RNA - RH-30 [nTPM]":"5.4","Cell RNA - RPMI-8226 [nTPM]":"4.0","Cell RNA - RPTEC TERT1 [nTPM]":"20.5","Cell RNA - RT4 [nTPM]":"12.9","Cell RNA - SCLC-21H [nTPM]":"7.3","Cell RNA - SH-SY5Y [nTPM]":"16.4","Cell RNA - SiHa [nTPM]":"11.9","Cell RNA - SK-BR-3 [nTPM]":"10.3","Cell RNA - SK-MEL-30 [nTPM]":"32.2","Cell RNA - SuSa [nTPM]":"9.9","Cell RNA - T-47d [nTPM]":"23.3","Cell RNA - THP-1 [nTPM]":"39.8","Cell RNA - TIME [nTPM]":"6.1","Cell RNA - U-138 MG [nTPM]":"13.9","Cell RNA - U-2 OS [nTPM]":"12.3","Cell RNA - U-2197 [nTPM]":"6.6","Cell RNA - U-251 MG [nTPM]":"15.2","Cell RNA - U-266\/70 [nTPM]":"21.2","Cell RNA - U-266\/84 [nTPM]":"17.4","Cell RNA - U-698 [nTPM]":"14.0","Cell RNA - U-87 MG [nTPM]":"22.3","Cell RNA - U-937 [nTPM]":"22.0","Cell RNA - WM-115 [nTPM]":"16.0","Blood RNA - basophil [nTPM]":"26.4","Blood RNA - classical monocyte [nTPM]":"15.3","Blood RNA - eosinophil [nTPM]":"23.9","Blood RNA - gdT-cell [nTPM]":"15.6","Blood RNA - intermediate monocyte [nTPM]":"27.5","Blood RNA - MAIT T-cell [nTPM]":"17.9","Blood RNA - memory B-cell [nTPM]":"13.9","Blood RNA - memory CD4 T-cell [nTPM]":"16.6","Blood RNA - memory CD8 T-cell [nTPM]":"18.8","Blood RNA - myeloid DC [nTPM]":"14.8","Blood RNA - naive B-cell [nTPM]":"12.9","Blood RNA - naive CD4 T-cell [nTPM]":"14.8","Blood RNA - naive CD8 T-cell [nTPM]":"21.3","Blood RNA - neutrophil [nTPM]":"3.3","Blood RNA - NK-cell [nTPM]":"12.7","Blood RNA - non-classical monocyte [nTPM]":"35.8","Blood RNA - plasmacytoid DC [nTPM]":"15.8","Blood RNA - T-reg [nTPM]":"17.8","Blood RNA - total PBMC [nTPM]":"15.1","Brain RNA - amygdala [nTPM]":"8.1","Brain RNA - basal ganglia [nTPM]":"10.4","Brain RNA - cerebellum [nTPM]":"9.8","Brain RNA - cerebral cortex [nTPM]":"12.0","Brain RNA - hippocampal formation [nTPM]":"8.4","Brain RNA - hypothalamus [nTPM]":"9.9","Brain RNA - medulla oblongata [nTPM]":"11.4","Brain RNA - midbrain [nTPM]":"9.1","Brain RNA - pons [nTPM]":"11.4","Brain RNA - spinal cord [nTPM]":"9.5","Brain RNA - thalamus [nTPM]":"8.6","Brain RNA - white matter [nTPM]":"13.7","Single Cell Type RNA - Adipocytes [nTPM]":"12.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.5","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"20.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"24.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"26.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Bipolar cells [nTPM]":"3.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"21.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"26.3","Single Cell Type RNA - dendritic cells [nTPM]":"17.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"28.2","Single Cell Type RNA - Early spermatids [nTPM]":"13.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.5","Single Cell Type RNA - Endothelial cells [nTPM]":"10.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"7.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"31.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"32.0","Single Cell Type RNA - Fibroblasts [nTPM]":"16.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.5","Single Cell Type RNA - granulocytes [nTPM]":"14.0","Single Cell Type RNA - Granulosa cells [nTPM]":"13.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.2","Single Cell Type RNA - Hepatocytes [nTPM]":"23.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.1","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.2","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"15.4","Single Cell Type RNA - Langerhans cells [nTPM]":"23.3","Single Cell Type RNA - Late spermatids [nTPM]":"9.2","Single Cell Type RNA - Leydig cells [nTPM]":"11.1","Single Cell Type RNA - Macrophages [nTPM]":"15.9","Single Cell Type RNA - Melanocytes [nTPM]":"39.2","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"23.8","Single Cell Type RNA - Muller glia cells [nTPM]":"19.1","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.4","Single Cell Type RNA - Paneth cells [nTPM]":"9.1","Single Cell Type RNA - Peritubular cells [nTPM]":"9.8","Single Cell Type RNA - Plasma cells [nTPM]":"48.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.1","Single Cell Type RNA - Spermatocytes [nTPM]":"35.8","Single Cell Type RNA - Spermatogonia [nTPM]":"36.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.7","Single Cell Type RNA - T-cells [nTPM]":"22.5","Single Cell Type RNA - Theca cells [nTPM]":"14.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.6","Single Cell Type RNA - Urothelial cells [nTPM]":"17.7"},{"Gene":"AGBL1","Gene synonym":["CCP4","FLJ32310"],"Ensembl":"ENSG00000273540","Gene description":"ATP\/GTP binding protein like 1","Uniprot":["Q96MI9"],"Chromosome":"15","Position":"86079871-87049169","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Carboxypeptidase","Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Corneal dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"skeletal muscle":"7.8","tongue":"23.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"16.7","Astrocytes":"28.7","Excitatory neurons":"15.6","Inhibitory neurons":"25.6","Oligodendrocyte precursor cells":"47.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.6","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"1.4","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.7","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.5","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"1.0","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.7","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"1.0","Tissue RNA - midbrain [nTPM]":"0.8","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.7","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"7.8","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"23.2","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.6","Brain RNA - basal ganglia [nTPM]":"1.4","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.7","Brain RNA - hippocampal formation [nTPM]":"1.0","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"1.0","Brain RNA - midbrain [nTPM]":"0.8","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.7","Single Cell Type RNA - Astrocytes [nTPM]":"28.7","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"47.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"AGBL5","Gene synonym":["CCP5","FLJ21839"],"Ensembl":"ENSG00000084693","Gene description":"ATP\/GTP binding protein like 5","Uniprot":["Q8NDL9"],"Chromosome":"2","Position":"27042364-27070622","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Carboxypeptidase","Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"parathyroid gland":"49.9","testis":"192.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Early spermatids":"302.7","Late spermatids":"338.0","Spermatocytes":"156.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030981"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Microtubules","Cytokinetic bridge","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Cytokinetic bridge"],"Subcellular additional location":["Microtubules","Cytosol"],"Antibody RRID":{"HPA030981":"AB_10611673"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.87e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.8","Tissue RNA - adrenal gland [nTPM]":"16.7","Tissue RNA - amygdala [nTPM]":"8.4","Tissue RNA - appendix [nTPM]":"8.0","Tissue RNA - basal ganglia [nTPM]":"7.4","Tissue RNA - bone marrow [nTPM]":"13.6","Tissue RNA - breast [nTPM]":"12.4","Tissue RNA - cerebellum [nTPM]":"7.8","Tissue RNA - cerebral cortex [nTPM]":"8.2","Tissue RNA - cervix [nTPM]":"14.4","Tissue RNA - choroid plexus [nTPM]":"9.5","Tissue RNA - colon [nTPM]":"16.2","Tissue RNA - duodenum [nTPM]":"8.8","Tissue RNA - endometrium 1 [nTPM]":"14.0","Tissue RNA - epididymis [nTPM]":"26.0","Tissue RNA - esophagus [nTPM]":"18.3","Tissue RNA - fallopian tube [nTPM]":"20.8","Tissue RNA - gallbladder [nTPM]":"14.3","Tissue RNA - heart muscle [nTPM]":"12.7","Tissue RNA - hippocampal formation [nTPM]":"7.3","Tissue RNA - hypothalamus [nTPM]":"11.3","Tissue RNA - kidney [nTPM]":"22.5","Tissue RNA - liver [nTPM]":"7.2","Tissue RNA - lung [nTPM]":"11.2","Tissue RNA - lymph node [nTPM]":"10.7","Tissue RNA - medulla oblongata [nTPM]":"8.3","Tissue RNA - midbrain [nTPM]":"7.8","Tissue RNA - ovary [nTPM]":"14.4","Tissue RNA - pancreas [nTPM]":"15.0","Tissue RNA - parathyroid gland [nTPM]":"49.9","Tissue RNA - pituitary gland [nTPM]":"12.5","Tissue RNA - placenta [nTPM]":"11.2","Tissue RNA - pons [nTPM]":"8.9","Tissue RNA - prostate [nTPM]":"15.2","Tissue RNA - rectum [nTPM]":"11.5","Tissue RNA - retina [nTPM]":"16.3","Tissue RNA - salivary gland [nTPM]":"21.2","Tissue RNA - seminal vesicle [nTPM]":"16.5","Tissue RNA - skeletal muscle [nTPM]":"7.1","Tissue RNA - skin 1 [nTPM]":"20.5","Tissue RNA - small intestine [nTPM]":"9.9","Tissue RNA - smooth muscle [nTPM]":"14.6","Tissue RNA - spinal cord [nTPM]":"6.1","Tissue RNA - spleen [nTPM]":"8.5","Tissue RNA - stomach 1 [nTPM]":"11.8","Tissue RNA - testis [nTPM]":"192.9","Tissue RNA - thalamus [nTPM]":"9.1","Tissue RNA - thymus [nTPM]":"15.6","Tissue RNA - thyroid gland [nTPM]":"28.5","Tissue RNA - tongue [nTPM]":"6.5","Tissue RNA - tonsil [nTPM]":"8.6","Tissue RNA - urinary bladder [nTPM]":"14.9","Tissue RNA - vagina [nTPM]":"7.3","Tissue RNA - white matter [nTPM]":"7.5","Cell RNA - A-431 [nTPM]":"55.0","Cell RNA - A549 [nTPM]":"34.7","Cell RNA - AF22 [nTPM]":"55.4","Cell RNA - AN3-CA [nTPM]":"37.2","Cell RNA - ASC diff [nTPM]":"11.6","Cell RNA - ASC TERT1 [nTPM]":"23.0","Cell RNA - BEWO [nTPM]":"62.9","Cell RNA - BJ [nTPM]":"10.9","Cell RNA - BJ hTERT+ [nTPM]":"23.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"30.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"31.9","Cell RNA - CACO-2 [nTPM]":"30.2","Cell RNA - CAPAN-2 [nTPM]":"40.5","Cell RNA - Daudi [nTPM]":"30.3","Cell RNA - EFO-21 [nTPM]":"34.0","Cell RNA - fHDF\/TERT166 [nTPM]":"18.9","Cell RNA - GAMG [nTPM]":"43.4","Cell RNA - HaCaT [nTPM]":"24.6","Cell RNA - HAP1 [nTPM]":"44.8","Cell RNA - HBEC3-KT [nTPM]":"49.4","Cell RNA - HBF TERT88 [nTPM]":"33.9","Cell RNA - HDLM-2 [nTPM]":"25.9","Cell RNA - HEK 293 [nTPM]":"66.8","Cell RNA - HEL [nTPM]":"44.5","Cell RNA - HeLa [nTPM]":"42.0","Cell RNA - Hep G2 [nTPM]":"65.7","Cell RNA - HHSteC [nTPM]":"23.6","Cell RNA - HL-60 [nTPM]":"21.6","Cell RNA - HMC-1 [nTPM]":"14.4","Cell RNA - HSkMC [nTPM]":"24.4","Cell RNA - hTCEpi [nTPM]":"36.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"27.1","Cell RNA - hTERT-HME1 [nTPM]":"22.0","Cell RNA - hTERT-RPE1 [nTPM]":"46.9","Cell RNA - HUVEC TERT2 [nTPM]":"32.8","Cell RNA - JURKAT [nTPM]":"43.5","Cell RNA - K-562 [nTPM]":"38.9","Cell RNA - Karpas-707 [nTPM]":"23.8","Cell RNA - LHCN-M2 [nTPM]":"30.3","Cell RNA - MCF7 [nTPM]":"21.5","Cell RNA - MOLT-4 [nTPM]":"63.2","Cell RNA - NB-4 [nTPM]":"32.3","Cell RNA - NTERA-2 [nTPM]":"39.4","Cell RNA - OE19 [nTPM]":"39.4","Cell RNA - PC-3 [nTPM]":"23.7","Cell RNA - REH [nTPM]":"64.5","Cell RNA - RH-30 [nTPM]":"62.9","Cell RNA - RPMI-8226 [nTPM]":"48.0","Cell RNA - RPTEC TERT1 [nTPM]":"31.9","Cell RNA - RT4 [nTPM]":"13.6","Cell RNA - SCLC-21H [nTPM]":"37.1","Cell RNA - SH-SY5Y [nTPM]":"53.6","Cell RNA - SiHa [nTPM]":"21.5","Cell RNA - SK-BR-3 [nTPM]":"16.7","Cell RNA - SK-MEL-30 [nTPM]":"35.0","Cell RNA - SuSa [nTPM]":"53.9","Cell RNA - T-47d [nTPM]":"24.9","Cell RNA - THP-1 [nTPM]":"16.3","Cell RNA - TIME [nTPM]":"16.4","Cell RNA - U-138 MG [nTPM]":"28.6","Cell RNA - U-2 OS [nTPM]":"39.2","Cell RNA - U-2197 [nTPM]":"13.8","Cell RNA - U-251 MG [nTPM]":"23.9","Cell RNA - U-266\/70 [nTPM]":"47.7","Cell RNA - U-266\/84 [nTPM]":"27.2","Cell RNA - U-698 [nTPM]":"62.4","Cell RNA - U-87 MG [nTPM]":"31.8","Cell RNA - U-937 [nTPM]":"24.4","Cell RNA - WM-115 [nTPM]":"26.1","Blood RNA - basophil [nTPM]":"8.8","Blood RNA - classical monocyte [nTPM]":"1.8","Blood RNA - eosinophil [nTPM]":"4.5","Blood RNA - gdT-cell [nTPM]":"3.3","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"2.5","Blood RNA - memory B-cell [nTPM]":"4.6","Blood RNA - memory CD4 T-cell [nTPM]":"4.1","Blood RNA - memory CD8 T-cell [nTPM]":"4.6","Blood RNA - myeloid DC [nTPM]":"4.1","Blood RNA - naive B-cell [nTPM]":"2.3","Blood RNA - naive CD4 T-cell [nTPM]":"3.6","Blood RNA - naive CD8 T-cell [nTPM]":"2.2","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"8.5","Blood RNA - non-classical monocyte [nTPM]":"0.7","Blood RNA - plasmacytoid DC [nTPM]":"2.3","Blood RNA - T-reg [nTPM]":"2.8","Blood RNA - total PBMC [nTPM]":"3.8","Brain RNA - amygdala [nTPM]":"8.4","Brain RNA - basal ganglia [nTPM]":"7.4","Brain RNA - cerebellum [nTPM]":"7.8","Brain RNA - cerebral cortex [nTPM]":"8.2","Brain RNA - hippocampal formation [nTPM]":"7.3","Brain RNA - hypothalamus [nTPM]":"11.3","Brain RNA - medulla oblongata [nTPM]":"8.3","Brain RNA - midbrain [nTPM]":"7.8","Brain RNA - pons [nTPM]":"8.9","Brain RNA - spinal cord [nTPM]":"6.1","Brain RNA - thalamus [nTPM]":"9.1","Brain RNA - white matter [nTPM]":"7.5","Single Cell Type RNA - Adipocytes [nTPM]":"3.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.1","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"6.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"5.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"6.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.7","Single Cell Type RNA - dendritic cells [nTPM]":"1.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"8.3","Single Cell Type RNA - Early spermatids [nTPM]":"302.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.9","Single Cell Type RNA - Endothelial cells [nTPM]":"4.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"11.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.9","Single Cell Type RNA - Fibroblasts [nTPM]":"6.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.8","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"14.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"4.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.4","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"3.1","Single Cell Type RNA - Langerhans cells [nTPM]":"3.5","Single Cell Type RNA - Late spermatids [nTPM]":"338.0","Single Cell Type RNA - Leydig cells [nTPM]":"10.5","Single Cell Type RNA - Macrophages [nTPM]":"8.0","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"4.9","Single Cell Type RNA - Muller glia cells [nTPM]":"6.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.0","Single Cell Type RNA - Paneth cells [nTPM]":"7.6","Single Cell Type RNA - Peritubular cells [nTPM]":"11.3","Single Cell Type RNA - Plasma cells [nTPM]":"17.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"25.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.0","Single Cell Type RNA - Spermatocytes [nTPM]":"156.8","Single Cell Type RNA - Spermatogonia [nTPM]":"41.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.3","Single Cell Type RNA - T-cells [nTPM]":"5.0","Single Cell Type RNA - Theca cells [nTPM]":"9.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.6","Single Cell Type RNA - Urothelial cells [nTPM]":"10.5"},{"Gene":"AGK","Gene synonym":["FLJ10842","MULK"],"Ensembl":"ENSG00000006530","Gene description":"Acylglycerol kinase","Uniprot":["Q53H12"],"Chromosome":"7","Position":"141551278-141655244","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":["Cardiomyopathy","Cataract","Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"43.4","Inhibitory neurons":"43.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"97.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020959","HPA053471"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Mitochondria"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA020959":"AB_1854206","HPA053471":"AB_2682164"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.1","Tissue RNA - adrenal gland [nTPM]":"14.7","Tissue RNA - amygdala [nTPM]":"9.4","Tissue RNA - appendix [nTPM]":"8.5","Tissue RNA - basal ganglia [nTPM]":"10.9","Tissue RNA - bone marrow [nTPM]":"5.6","Tissue RNA - breast [nTPM]":"11.9","Tissue RNA - cerebellum [nTPM]":"8.3","Tissue RNA - cerebral cortex [nTPM]":"12.8","Tissue RNA - cervix [nTPM]":"11.5","Tissue RNA - choroid plexus [nTPM]":"10.2","Tissue RNA - colon [nTPM]":"11.8","Tissue RNA - duodenum [nTPM]":"5.9","Tissue RNA - endometrium 1 [nTPM]":"11.7","Tissue RNA - epididymis [nTPM]":"14.5","Tissue RNA - esophagus [nTPM]":"12.2","Tissue RNA - fallopian tube [nTPM]":"12.2","Tissue RNA - gallbladder [nTPM]":"7.8","Tissue RNA - heart muscle [nTPM]":"30.4","Tissue RNA - hippocampal formation [nTPM]":"11.1","Tissue RNA - hypothalamus [nTPM]":"10.8","Tissue RNA - kidney [nTPM]":"15.7","Tissue RNA - liver [nTPM]":"14.1","Tissue RNA - lung [nTPM]":"11.6","Tissue RNA - lymph node [nTPM]":"12.1","Tissue RNA - medulla oblongata [nTPM]":"8.0","Tissue RNA - midbrain [nTPM]":"8.8","Tissue RNA - ovary [nTPM]":"11.3","Tissue RNA - pancreas [nTPM]":"10.1","Tissue RNA - parathyroid gland [nTPM]":"21.5","Tissue RNA - pituitary gland [nTPM]":"13.7","Tissue RNA - placenta [nTPM]":"10.0","Tissue RNA - pons [nTPM]":"9.0","Tissue RNA - prostate [nTPM]":"12.8","Tissue RNA - rectum [nTPM]":"13.1","Tissue RNA - retina [nTPM]":"12.7","Tissue RNA - salivary gland [nTPM]":"13.7","Tissue RNA - seminal vesicle [nTPM]":"11.4","Tissue RNA - skeletal muscle [nTPM]":"8.6","Tissue RNA - skin 1 [nTPM]":"9.6","Tissue RNA - small intestine [nTPM]":"12.0","Tissue RNA - smooth muscle [nTPM]":"15.4","Tissue RNA - spinal cord [nTPM]":"8.2","Tissue RNA - spleen [nTPM]":"16.6","Tissue RNA - stomach 1 [nTPM]":"12.2","Tissue RNA - testis [nTPM]":"6.6","Tissue RNA - thalamus [nTPM]":"10.0","Tissue RNA - thymus [nTPM]":"14.0","Tissue RNA - thyroid gland [nTPM]":"12.7","Tissue RNA - tongue [nTPM]":"10.0","Tissue RNA - tonsil [nTPM]":"14.7","Tissue RNA - urinary bladder [nTPM]":"10.8","Tissue RNA - vagina [nTPM]":"11.5","Tissue RNA - white matter [nTPM]":"9.0","Cell RNA - A-431 [nTPM]":"23.7","Cell RNA - A549 [nTPM]":"25.6","Cell RNA - AF22 [nTPM]":"26.7","Cell RNA - AN3-CA [nTPM]":"21.8","Cell RNA - ASC diff [nTPM]":"21.2","Cell RNA - ASC TERT1 [nTPM]":"29.4","Cell RNA - BEWO [nTPM]":"16.2","Cell RNA - BJ [nTPM]":"23.5","Cell RNA - BJ hTERT+ [nTPM]":"29.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"44.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"50.9","Cell RNA - CACO-2 [nTPM]":"24.7","Cell RNA - CAPAN-2 [nTPM]":"18.3","Cell RNA - Daudi [nTPM]":"26.3","Cell RNA - EFO-21 [nTPM]":"24.0","Cell RNA - fHDF\/TERT166 [nTPM]":"26.8","Cell RNA - GAMG [nTPM]":"40.5","Cell RNA - HaCaT [nTPM]":"18.7","Cell RNA - HAP1 [nTPM]":"41.6","Cell RNA - HBEC3-KT [nTPM]":"32.8","Cell RNA - HBF TERT88 [nTPM]":"51.0","Cell RNA - HDLM-2 [nTPM]":"33.8","Cell RNA - HEK 293 [nTPM]":"32.7","Cell RNA - HEL [nTPM]":"26.1","Cell RNA - HeLa [nTPM]":"10.7","Cell RNA - Hep G2 [nTPM]":"18.7","Cell RNA - HHSteC [nTPM]":"34.1","Cell RNA - HL-60 [nTPM]":"15.6","Cell RNA - HMC-1 [nTPM]":"12.5","Cell RNA - HSkMC [nTPM]":"29.9","Cell RNA - hTCEpi [nTPM]":"26.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"36.3","Cell RNA - hTERT-HME1 [nTPM]":"33.1","Cell RNA - hTERT-RPE1 [nTPM]":"19.8","Cell RNA - HUVEC TERT2 [nTPM]":"34.1","Cell RNA - JURKAT [nTPM]":"32.3","Cell RNA - K-562 [nTPM]":"36.3","Cell RNA - Karpas-707 [nTPM]":"36.9","Cell RNA - LHCN-M2 [nTPM]":"25.3","Cell RNA - MCF7 [nTPM]":"24.6","Cell RNA - MOLT-4 [nTPM]":"47.3","Cell RNA - NB-4 [nTPM]":"9.1","Cell RNA - NTERA-2 [nTPM]":"25.6","Cell RNA - OE19 [nTPM]":"19.9","Cell RNA - PC-3 [nTPM]":"32.4","Cell RNA - REH [nTPM]":"29.2","Cell RNA - RH-30 [nTPM]":"4.2","Cell RNA - RPMI-8226 [nTPM]":"80.1","Cell RNA - RPTEC TERT1 [nTPM]":"33.1","Cell RNA - RT4 [nTPM]":"20.8","Cell RNA - SCLC-21H [nTPM]":"23.3","Cell RNA - SH-SY5Y [nTPM]":"29.6","Cell RNA - SiHa [nTPM]":"24.6","Cell RNA - SK-BR-3 [nTPM]":"29.7","Cell RNA - SK-MEL-30 [nTPM]":"27.1","Cell RNA - SuSa [nTPM]":"26.1","Cell RNA - T-47d [nTPM]":"16.3","Cell RNA - THP-1 [nTPM]":"20.2","Cell RNA - TIME [nTPM]":"19.5","Cell RNA - U-138 MG [nTPM]":"18.9","Cell RNA - U-2 OS [nTPM]":"14.1","Cell RNA - U-2197 [nTPM]":"23.8","Cell RNA - U-251 MG [nTPM]":"38.1","Cell RNA - U-266\/70 [nTPM]":"29.5","Cell RNA - U-266\/84 [nTPM]":"31.9","Cell RNA - U-698 [nTPM]":"14.4","Cell RNA - U-87 MG [nTPM]":"30.7","Cell RNA - U-937 [nTPM]":"9.1","Cell RNA - WM-115 [nTPM]":"50.4","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"7.1","Blood RNA - eosinophil [nTPM]":"1.2","Blood RNA - gdT-cell [nTPM]":"22.1","Blood RNA - intermediate monocyte [nTPM]":"13.9","Blood RNA - MAIT T-cell [nTPM]":"15.3","Blood RNA - memory B-cell [nTPM]":"10.8","Blood RNA - memory CD4 T-cell [nTPM]":"17.3","Blood RNA - memory CD8 T-cell [nTPM]":"26.0","Blood RNA - myeloid DC [nTPM]":"16.2","Blood RNA - naive B-cell [nTPM]":"6.5","Blood RNA - naive CD4 T-cell [nTPM]":"12.8","Blood RNA - naive CD8 T-cell [nTPM]":"23.5","Blood RNA - neutrophil [nTPM]":"1.2","Blood RNA - NK-cell [nTPM]":"97.3","Blood RNA - non-classical monocyte [nTPM]":"8.2","Blood RNA - plasmacytoid DC [nTPM]":"6.3","Blood RNA - T-reg [nTPM]":"18.9","Blood RNA - total PBMC [nTPM]":"15.7","Brain RNA - amygdala [nTPM]":"9.4","Brain RNA - basal ganglia [nTPM]":"10.9","Brain RNA - cerebellum [nTPM]":"8.3","Brain RNA - cerebral cortex [nTPM]":"12.8","Brain RNA - hippocampal formation [nTPM]":"11.1","Brain RNA - hypothalamus [nTPM]":"10.8","Brain RNA - medulla oblongata [nTPM]":"8.0","Brain RNA - midbrain [nTPM]":"8.8","Brain RNA - pons [nTPM]":"9.0","Brain RNA - spinal cord [nTPM]":"8.2","Brain RNA - thalamus [nTPM]":"10.0","Brain RNA - white matter [nTPM]":"9.0","Single Cell Type RNA - Adipocytes [nTPM]":"8.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.0","Single Cell Type RNA - Astrocytes [nTPM]":"22.5","Single Cell Type RNA - B-cells [nTPM]":"11.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"11.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"6.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.7","Single Cell Type RNA - dendritic cells [nTPM]":"15.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"6.6","Single Cell Type RNA - Early spermatids [nTPM]":"9.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.0","Single Cell Type RNA - Endothelial cells [nTPM]":"7.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"11.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"43.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.2","Single Cell Type RNA - Fibroblasts [nTPM]":"7.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.6","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"9.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.2","Single Cell Type RNA - Hepatocytes [nTPM]":"4.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.0","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"43.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.9","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.1","Single Cell Type RNA - Langerhans cells [nTPM]":"4.9","Single Cell Type RNA - Late spermatids [nTPM]":"12.0","Single Cell Type RNA - Leydig cells [nTPM]":"6.8","Single Cell Type RNA - Macrophages [nTPM]":"5.6","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"26.2","Single Cell Type RNA - monocytes [nTPM]":"12.4","Single Cell Type RNA - Muller glia cells [nTPM]":"11.2","Single Cell Type RNA - NK-cells [nTPM]":"27.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"38.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"37.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.1","Single Cell Type RNA - Paneth cells [nTPM]":"2.1","Single Cell Type RNA - Peritubular cells [nTPM]":"10.5","Single Cell Type RNA - Plasma cells [nTPM]":"22.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.0","Single Cell Type RNA - Spermatocytes [nTPM]":"6.2","Single Cell Type RNA - Spermatogonia [nTPM]":"4.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.2","Single Cell Type RNA - T-cells [nTPM]":"15.0","Single Cell Type RNA - Theca cells [nTPM]":"14.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.6","Single Cell Type RNA - Urothelial cells [nTPM]":"3.8"},{"Gene":"AGL","Gene synonym":[],"Ensembl":"ENSG00000162688","Gene description":"Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase","Uniprot":["P35573"],"Chromosome":"1","Position":"99850361-99924023","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Glycogen biosynthesis"],"Molecular function":["Glycosidase","Glycosyltransferase","Hydrolase","Multifunctional enzyme","Transferase"],"Disease involvement":["Disease variant","Glycogen storage disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"skeletal muscle":"257.6","tongue":"212.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Muller glia cells":"160.5","Theca cells":"159.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028498","HPA054340"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"450000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 5: Muller glia cells - Visual perception","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies","Cytosol"],"Antibody RRID":{"HPA028498":"AB_10600975","HPA054340":"AB_2682455"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.37e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.73e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.13e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.9","Tissue RNA - adrenal gland [nTPM]":"6.7","Tissue RNA - amygdala [nTPM]":"4.1","Tissue RNA - appendix [nTPM]":"7.1","Tissue RNA - basal ganglia [nTPM]":"4.9","Tissue RNA - bone marrow [nTPM]":"6.1","Tissue RNA - breast [nTPM]":"9.1","Tissue RNA - cerebellum [nTPM]":"6.9","Tissue RNA - cerebral cortex [nTPM]":"5.6","Tissue RNA - cervix [nTPM]":"6.1","Tissue RNA - choroid plexus [nTPM]":"6.0","Tissue RNA - colon [nTPM]":"10.0","Tissue RNA - duodenum [nTPM]":"8.8","Tissue RNA - endometrium 1 [nTPM]":"7.3","Tissue RNA - epididymis [nTPM]":"7.6","Tissue RNA - esophagus [nTPM]":"16.4","Tissue RNA - fallopian tube [nTPM]":"5.4","Tissue RNA - gallbladder [nTPM]":"5.2","Tissue RNA - heart muscle [nTPM]":"22.8","Tissue RNA - hippocampal formation [nTPM]":"3.7","Tissue RNA - hypothalamus [nTPM]":"5.1","Tissue RNA - kidney [nTPM]":"13.3","Tissue RNA - liver [nTPM]":"42.8","Tissue RNA - lung [nTPM]":"5.9","Tissue RNA - lymph node [nTPM]":"7.3","Tissue RNA - medulla oblongata [nTPM]":"4.7","Tissue RNA - midbrain [nTPM]":"5.6","Tissue RNA - ovary [nTPM]":"5.9","Tissue RNA - pancreas [nTPM]":"4.3","Tissue RNA - parathyroid gland [nTPM]":"17.6","Tissue RNA - pituitary gland [nTPM]":"4.5","Tissue RNA - placenta [nTPM]":"11.7","Tissue RNA - pons [nTPM]":"4.4","Tissue RNA - prostate [nTPM]":"13.8","Tissue RNA - rectum [nTPM]":"10.6","Tissue RNA - retina [nTPM]":"23.3","Tissue RNA - salivary gland [nTPM]":"7.7","Tissue RNA - seminal vesicle [nTPM]":"9.6","Tissue RNA - skeletal muscle [nTPM]":"257.6","Tissue RNA - skin 1 [nTPM]":"5.3","Tissue RNA - small intestine [nTPM]":"7.1","Tissue RNA - smooth muscle [nTPM]":"9.7","Tissue RNA - spinal cord [nTPM]":"4.9","Tissue RNA - spleen [nTPM]":"8.0","Tissue RNA - stomach 1 [nTPM]":"7.7","Tissue RNA - testis [nTPM]":"4.7","Tissue RNA - thalamus [nTPM]":"4.8","Tissue RNA - thymus [nTPM]":"7.9","Tissue RNA - thyroid gland [nTPM]":"10.5","Tissue RNA - tongue [nTPM]":"212.0","Tissue RNA - tonsil [nTPM]":"8.5","Tissue RNA - urinary bladder [nTPM]":"8.9","Tissue RNA - vagina [nTPM]":"5.0","Tissue RNA - white matter [nTPM]":"5.6","Cell RNA - A-431 [nTPM]":"20.4","Cell RNA - A549 [nTPM]":"5.9","Cell RNA - AF22 [nTPM]":"7.0","Cell RNA - AN3-CA [nTPM]":"11.4","Cell RNA - ASC diff [nTPM]":"11.0","Cell RNA - ASC TERT1 [nTPM]":"10.4","Cell RNA - BEWO [nTPM]":"23.4","Cell RNA - BJ [nTPM]":"6.3","Cell RNA - BJ hTERT+ [nTPM]":"9.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.8","Cell RNA - CACO-2 [nTPM]":"22.3","Cell RNA - CAPAN-2 [nTPM]":"6.8","Cell RNA - Daudi [nTPM]":"26.4","Cell RNA - EFO-21 [nTPM]":"11.7","Cell RNA - fHDF\/TERT166 [nTPM]":"10.8","Cell RNA - GAMG [nTPM]":"4.9","Cell RNA - HaCaT [nTPM]":"11.3","Cell RNA - HAP1 [nTPM]":"40.5","Cell RNA - HBEC3-KT [nTPM]":"12.4","Cell RNA - HBF TERT88 [nTPM]":"10.2","Cell RNA - HDLM-2 [nTPM]":"14.2","Cell RNA - HEK 293 [nTPM]":"12.9","Cell RNA - HEL [nTPM]":"15.5","Cell RNA - HeLa [nTPM]":"18.9","Cell RNA - Hep G2 [nTPM]":"12.4","Cell RNA - HHSteC [nTPM]":"7.3","Cell RNA - HL-60 [nTPM]":"13.7","Cell RNA - HMC-1 [nTPM]":"8.9","Cell RNA - HSkMC [nTPM]":"12.8","Cell RNA - hTCEpi [nTPM]":"7.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.5","Cell RNA - hTERT-HME1 [nTPM]":"6.2","Cell RNA - hTERT-RPE1 [nTPM]":"7.5","Cell RNA - HUVEC TERT2 [nTPM]":"8.5","Cell RNA - JURKAT [nTPM]":"9.2","Cell RNA - K-562 [nTPM]":"26.3","Cell RNA - Karpas-707 [nTPM]":"2.0","Cell RNA - LHCN-M2 [nTPM]":"5.5","Cell RNA - MCF7 [nTPM]":"6.2","Cell RNA - MOLT-4 [nTPM]":"16.3","Cell RNA - NB-4 [nTPM]":"4.3","Cell RNA - NTERA-2 [nTPM]":"10.9","Cell RNA - OE19 [nTPM]":"8.9","Cell RNA - PC-3 [nTPM]":"7.7","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"2.3","Cell RNA - RPMI-8226 [nTPM]":"1.3","Cell RNA - RPTEC TERT1 [nTPM]":"16.3","Cell RNA - RT4 [nTPM]":"26.7","Cell RNA - SCLC-21H [nTPM]":"17.2","Cell RNA - SH-SY5Y [nTPM]":"12.1","Cell RNA - SiHa [nTPM]":"18.2","Cell RNA - SK-BR-3 [nTPM]":"17.3","Cell RNA - SK-MEL-30 [nTPM]":"9.9","Cell RNA - SuSa [nTPM]":"12.8","Cell RNA - T-47d [nTPM]":"12.6","Cell RNA - THP-1 [nTPM]":"9.0","Cell RNA - TIME [nTPM]":"9.4","Cell RNA - U-138 MG [nTPM]":"6.6","Cell RNA - U-2 OS [nTPM]":"9.3","Cell RNA - U-2197 [nTPM]":"8.9","Cell RNA - U-251 MG [nTPM]":"6.3","Cell RNA - U-266\/70 [nTPM]":"7.3","Cell RNA - U-266\/84 [nTPM]":"6.1","Cell RNA - U-698 [nTPM]":"30.5","Cell RNA - U-87 MG [nTPM]":"11.7","Cell RNA - U-937 [nTPM]":"3.6","Cell RNA - WM-115 [nTPM]":"3.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"1.4","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"1.4","Blood RNA - memory B-cell [nTPM]":"1.0","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.0","Blood RNA - myeloid DC [nTPM]":"0.9","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.1","Blood RNA - naive CD8 T-cell [nTPM]":"1.1","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"2.4","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"1.3","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"4.1","Brain RNA - basal ganglia [nTPM]":"4.9","Brain RNA - cerebellum [nTPM]":"6.9","Brain RNA - cerebral cortex [nTPM]":"5.6","Brain RNA - hippocampal formation [nTPM]":"3.7","Brain RNA - hypothalamus [nTPM]":"5.1","Brain RNA - medulla oblongata [nTPM]":"4.7","Brain RNA - midbrain [nTPM]":"5.6","Brain RNA - pons [nTPM]":"4.4","Brain RNA - spinal cord [nTPM]":"4.9","Brain RNA - thalamus [nTPM]":"4.8","Brain RNA - white matter [nTPM]":"5.6","Single Cell Type RNA - Adipocytes [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.8","Single Cell Type RNA - Astrocytes [nTPM]":"96.6","Single Cell Type RNA - B-cells [nTPM]":"28.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"24.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.2","Single Cell Type RNA - Bipolar cells [nTPM]":"34.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"119.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"25.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"54.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"107.9","Single Cell Type RNA - dendritic cells [nTPM]":"18.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"13.7","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.6","Single Cell Type RNA - Endothelial cells [nTPM]":"13.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.8","Single Cell Type RNA - Erythroid cells [nTPM]":"15.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"45.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.3","Single Cell Type RNA - Fibroblasts [nTPM]":"28.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"31.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.6","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"45.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"111.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.9","Single Cell Type RNA - Horizontal cells [nTPM]":"52.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"56.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.8","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"19.1","Single Cell Type RNA - Langerhans cells [nTPM]":"8.8","Single Cell Type RNA - Late spermatids [nTPM]":"2.5","Single Cell Type RNA - Leydig cells [nTPM]":"10.2","Single Cell Type RNA - Macrophages [nTPM]":"13.5","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"14.1","Single Cell Type RNA - Muller glia cells [nTPM]":"160.5","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"36.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"34.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.7","Single Cell Type RNA - Paneth cells [nTPM]":"14.3","Single Cell Type RNA - Peritubular cells [nTPM]":"21.4","Single Cell Type RNA - Plasma cells [nTPM]":"20.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"26.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"46.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"41.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.4","Single Cell Type RNA - Spermatocytes [nTPM]":"8.7","Single Cell Type RNA - Spermatogonia [nTPM]":"11.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"40.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"29.1","Single Cell Type RNA - T-cells [nTPM]":"25.7","Single Cell Type RNA - Theca cells [nTPM]":"159.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.5","Single Cell Type RNA - Urothelial cells [nTPM]":"20.1"},{"Gene":"AGPAT2","Gene synonym":["BSCL","LPAAT-beta"],"Ensembl":"ENSG00000169692","Gene description":"1-acylglycerol-3-phosphate O-acyltransferase 2","Uniprot":["O15120"],"Chromosome":"9","Position":"136673143-136687457","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Congenital generalized lipodystrophy","Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"369.3","liver":"445.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"688.9","Late spermatids":"387.3","Paneth cells":"670.7","Proximal enterocytes":"1298.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"186.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019544"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA019544":"AB_1844646"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.30e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Tissue RNA - adipose tissue [nTPM]":"369.3","Tissue RNA - adrenal gland [nTPM]":"38.3","Tissue RNA - amygdala [nTPM]":"11.4","Tissue RNA - appendix [nTPM]":"11.8","Tissue RNA - basal ganglia [nTPM]":"9.3","Tissue RNA - bone marrow [nTPM]":"34.2","Tissue RNA - breast [nTPM]":"259.9","Tissue RNA - cerebellum [nTPM]":"8.8","Tissue RNA - cerebral cortex [nTPM]":"15.9","Tissue RNA - cervix [nTPM]":"32.1","Tissue RNA - choroid plexus [nTPM]":"13.5","Tissue RNA - colon [nTPM]":"83.2","Tissue RNA - duodenum [nTPM]":"111.4","Tissue RNA - endometrium 1 [nTPM]":"26.4","Tissue RNA - epididymis [nTPM]":"9.6","Tissue RNA - esophagus [nTPM]":"85.6","Tissue RNA - fallopian tube [nTPM]":"29.7","Tissue RNA - gallbladder [nTPM]":"15.7","Tissue RNA - heart muscle [nTPM]":"84.9","Tissue RNA - hippocampal formation [nTPM]":"9.4","Tissue RNA - hypothalamus [nTPM]":"12.6","Tissue RNA - kidney [nTPM]":"80.2","Tissue RNA - liver [nTPM]":"445.0","Tissue RNA - lung [nTPM]":"60.9","Tissue RNA - lymph node [nTPM]":"9.2","Tissue RNA - medulla oblongata [nTPM]":"11.8","Tissue RNA - midbrain [nTPM]":"12.3","Tissue RNA - ovary [nTPM]":"17.7","Tissue RNA - pancreas [nTPM]":"129.6","Tissue RNA - parathyroid gland [nTPM]":"18.4","Tissue RNA - pituitary gland [nTPM]":"41.5","Tissue RNA - placenta [nTPM]":"8.0","Tissue RNA - pons [nTPM]":"11.3","Tissue RNA - prostate [nTPM]":"34.3","Tissue RNA - rectum [nTPM]":"12.2","Tissue RNA - retina [nTPM]":"0.9","Tissue RNA - salivary gland [nTPM]":"48.1","Tissue RNA - seminal vesicle [nTPM]":"12.8","Tissue RNA - skeletal muscle [nTPM]":"37.4","Tissue RNA - skin 1 [nTPM]":"51.1","Tissue RNA - small intestine [nTPM]":"119.4","Tissue RNA - smooth muscle [nTPM]":"6.7","Tissue RNA - spinal cord [nTPM]":"11.4","Tissue RNA - spleen [nTPM]":"39.2","Tissue RNA - stomach 1 [nTPM]":"52.0","Tissue RNA - testis [nTPM]":"24.1","Tissue RNA - thalamus [nTPM]":"13.9","Tissue RNA - thymus [nTPM]":"5.5","Tissue RNA - thyroid gland [nTPM]":"46.9","Tissue RNA - tongue [nTPM]":"10.0","Tissue RNA - tonsil [nTPM]":"5.3","Tissue RNA - urinary bladder [nTPM]":"35.5","Tissue RNA - vagina [nTPM]":"36.6","Tissue RNA - white matter [nTPM]":"9.6","Cell RNA - A-431 [nTPM]":"55.0","Cell RNA - A549 [nTPM]":"75.2","Cell RNA - AF22 [nTPM]":"8.9","Cell RNA - AN3-CA [nTPM]":"41.4","Cell RNA - ASC diff [nTPM]":"63.3","Cell RNA - ASC TERT1 [nTPM]":"19.8","Cell RNA - BEWO [nTPM]":"37.3","Cell RNA - BJ [nTPM]":"35.5","Cell RNA - BJ hTERT+ [nTPM]":"28.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"18.5","Cell RNA - CACO-2 [nTPM]":"86.0","Cell RNA - CAPAN-2 [nTPM]":"105.7","Cell RNA - Daudi [nTPM]":"17.8","Cell RNA - EFO-21 [nTPM]":"77.8","Cell RNA - fHDF\/TERT166 [nTPM]":"21.0","Cell RNA - GAMG [nTPM]":"38.6","Cell RNA - HaCaT [nTPM]":"145.1","Cell RNA - HAP1 [nTPM]":"12.7","Cell RNA - HBEC3-KT [nTPM]":"22.2","Cell RNA - HBF TERT88 [nTPM]":"2.8","Cell RNA - HDLM-2 [nTPM]":"186.9","Cell RNA - HEK 293 [nTPM]":"57.3","Cell RNA - HEL [nTPM]":"26.5","Cell RNA - HeLa [nTPM]":"30.3","Cell RNA - Hep G2 [nTPM]":"19.2","Cell RNA - HHSteC [nTPM]":"42.6","Cell RNA - HL-60 [nTPM]":"28.1","Cell RNA - HMC-1 [nTPM]":"62.1","Cell RNA - HSkMC [nTPM]":"19.0","Cell RNA - hTCEpi [nTPM]":"30.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.9","Cell RNA - hTERT-HME1 [nTPM]":"11.0","Cell RNA - hTERT-RPE1 [nTPM]":"20.9","Cell RNA - HUVEC TERT2 [nTPM]":"12.5","Cell RNA - JURKAT [nTPM]":"23.6","Cell RNA - K-562 [nTPM]":"32.7","Cell RNA - Karpas-707 [nTPM]":"2.9","Cell RNA - LHCN-M2 [nTPM]":"10.4","Cell RNA - MCF7 [nTPM]":"98.5","Cell RNA - MOLT-4 [nTPM]":"1.9","Cell RNA - NB-4 [nTPM]":"87.4","Cell RNA - NTERA-2 [nTPM]":"22.5","Cell RNA - OE19 [nTPM]":"101.0","Cell RNA - PC-3 [nTPM]":"135.0","Cell RNA - REH [nTPM]":"41.0","Cell RNA - RH-30 [nTPM]":"31.3","Cell RNA - RPMI-8226 [nTPM]":"100.3","Cell RNA - RPTEC TERT1 [nTPM]":"28.5","Cell RNA - RT4 [nTPM]":"33.9","Cell RNA - SCLC-21H [nTPM]":"19.5","Cell RNA - SH-SY5Y [nTPM]":"31.4","Cell RNA - SiHa [nTPM]":"45.8","Cell RNA - SK-BR-3 [nTPM]":"47.6","Cell RNA - SK-MEL-30 [nTPM]":"60.3","Cell RNA - SuSa [nTPM]":"6.8","Cell RNA - T-47d [nTPM]":"30.6","Cell RNA - THP-1 [nTPM]":"109.3","Cell RNA - TIME [nTPM]":"24.7","Cell RNA - U-138 MG [nTPM]":"31.5","Cell RNA - U-2 OS [nTPM]":"32.1","Cell RNA - U-2197 [nTPM]":"10.4","Cell RNA - U-251 MG [nTPM]":"23.0","Cell RNA - U-266\/70 [nTPM]":"4.4","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"11.8","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"59.7","Cell RNA - WM-115 [nTPM]":"32.1","Blood RNA - basophil [nTPM]":"20.1","Blood RNA - classical monocyte [nTPM]":"88.8","Blood RNA - eosinophil [nTPM]":"111.8","Blood RNA - gdT-cell [nTPM]":"6.8","Blood RNA - intermediate monocyte [nTPM]":"83.5","Blood RNA - MAIT T-cell [nTPM]":"6.5","Blood RNA - memory B-cell [nTPM]":"12.8","Blood RNA - memory CD4 T-cell [nTPM]":"5.8","Blood RNA - memory CD8 T-cell [nTPM]":"7.9","Blood RNA - myeloid DC [nTPM]":"47.8","Blood RNA - naive B-cell [nTPM]":"22.7","Blood RNA - naive CD4 T-cell [nTPM]":"4.6","Blood RNA - naive CD8 T-cell [nTPM]":"5.5","Blood RNA - neutrophil [nTPM]":"61.1","Blood RNA - NK-cell [nTPM]":"7.2","Blood RNA - non-classical monocyte [nTPM]":"75.7","Blood RNA - plasmacytoid DC [nTPM]":"65.6","Blood RNA - T-reg [nTPM]":"8.1","Blood RNA - total PBMC [nTPM]":"35.2","Brain RNA - amygdala [nTPM]":"11.4","Brain RNA - basal ganglia [nTPM]":"9.3","Brain RNA - cerebellum [nTPM]":"8.8","Brain RNA - cerebral cortex [nTPM]":"15.9","Brain RNA - hippocampal formation [nTPM]":"9.4","Brain RNA - hypothalamus [nTPM]":"12.6","Brain RNA - medulla oblongata [nTPM]":"11.8","Brain RNA - midbrain [nTPM]":"12.3","Brain RNA - pons [nTPM]":"11.3","Brain RNA - spinal cord [nTPM]":"11.4","Brain RNA - thalamus [nTPM]":"13.9","Brain RNA - white matter [nTPM]":"9.6","Single Cell Type RNA - Adipocytes [nTPM]":"25.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"64.4","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"20.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"45.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"60.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"64.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.8","Single Cell Type RNA - Bipolar cells [nTPM]":"3.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"22.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"39.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"87.2","Single Cell Type RNA - Club cells [nTPM]":"45.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"73.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.3","Single Cell Type RNA - dendritic cells [nTPM]":"30.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"688.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"54.8","Single Cell Type RNA - Ductal cells [nTPM]":"155.2","Single Cell Type RNA - Early spermatids [nTPM]":"136.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"50.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.4","Single Cell Type RNA - Endothelial cells [nTPM]":"27.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"35.8","Single Cell Type RNA - Erythroid cells [nTPM]":"8.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"219.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"37.1","Single Cell Type RNA - Fibroblasts [nTPM]":"30.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"81.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"63.8","Single Cell Type RNA - granulocytes [nTPM]":"13.4","Single Cell Type RNA - Granulosa cells [nTPM]":"31.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"31.1","Single Cell Type RNA - Hepatocytes [nTPM]":"228.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"131.2","Single Cell Type RNA - Horizontal cells [nTPM]":"40.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"197.3","Single Cell Type RNA - Ionocytes [nTPM]":"126.1","Single Cell Type RNA - Kupffer cells [nTPM]":"53.4","Single Cell Type RNA - Langerhans cells [nTPM]":"57.4","Single Cell Type RNA - Late spermatids [nTPM]":"387.3","Single Cell Type RNA - Leydig cells [nTPM]":"26.8","Single Cell Type RNA - Macrophages [nTPM]":"57.6","Single Cell Type RNA - Melanocytes [nTPM]":"136.9","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"48.8","Single Cell Type RNA - Muller glia cells [nTPM]":"14.6","Single Cell Type RNA - NK-cells [nTPM]":"23.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"169.5","Single Cell Type RNA - Paneth cells [nTPM]":"670.7","Single Cell Type RNA - Peritubular cells [nTPM]":"20.3","Single Cell Type RNA - Plasma cells [nTPM]":"13.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"93.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1298.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"41.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"46.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.8","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"29.8","Single Cell Type RNA - Spermatocytes [nTPM]":"1.8","Single Cell Type RNA - Spermatogonia [nTPM]":"27.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"47.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"81.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.8","Single Cell Type RNA - T-cells [nTPM]":"26.6","Single Cell Type RNA - Theca cells [nTPM]":"16.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"207.7","Single Cell Type RNA - Urothelial cells [nTPM]":"196.2"},{"Gene":"AGPS","Gene synonym":["ADAP-S","ADAS","ADHAPS","ADPS","ALDHPSY"],"Ensembl":"ENSG00000018510","Gene description":"Alkylglycerone phosphate synthase","Uniprot":["O00116"],"Chromosome":"2","Position":"177392746-177567024","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Cataract","Disease variant","Dwarfism","Rhizomelic chondrodysplasia punctata"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"262.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030209","HPA030210","HPA030211"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Peroxisomes"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"69000","Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 23: Spermatids - Flagellum & Golgi organization","Subcellular main location":["Peroxisomes"],"Subcellular additional location":null,"Antibody RRID":{"HPA030209":"AB_10600634","HPA030210":"AB_10600202","HPA030211":"AB_10602195"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.62e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.35e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.45e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Tissue RNA - adipose tissue [nTPM]":"14.3","Tissue RNA - adrenal gland [nTPM]":"9.2","Tissue RNA - amygdala [nTPM]":"4.4","Tissue RNA - appendix [nTPM]":"15.6","Tissue RNA - basal ganglia [nTPM]":"6.9","Tissue RNA - bone marrow [nTPM]":"19.6","Tissue RNA - breast [nTPM]":"13.9","Tissue RNA - cerebellum [nTPM]":"7.1","Tissue RNA - cerebral cortex [nTPM]":"6.9","Tissue RNA - cervix [nTPM]":"14.3","Tissue RNA - choroid plexus [nTPM]":"4.6","Tissue RNA - colon [nTPM]":"20.1","Tissue RNA - duodenum [nTPM]":"11.1","Tissue RNA - endometrium 1 [nTPM]":"14.6","Tissue RNA - epididymis [nTPM]":"6.5","Tissue RNA - esophagus [nTPM]":"12.7","Tissue RNA - fallopian tube [nTPM]":"9.8","Tissue RNA - gallbladder [nTPM]":"11.3","Tissue RNA - heart muscle [nTPM]":"10.4","Tissue RNA - hippocampal formation [nTPM]":"4.7","Tissue RNA - hypothalamus [nTPM]":"6.6","Tissue RNA - kidney [nTPM]":"18.1","Tissue RNA - liver [nTPM]":"19.3","Tissue RNA - lung [nTPM]":"13.7","Tissue RNA - lymph node [nTPM]":"11.9","Tissue RNA - medulla oblongata [nTPM]":"8.9","Tissue RNA - midbrain [nTPM]":"7.0","Tissue RNA - ovary [nTPM]":"7.8","Tissue RNA - pancreas [nTPM]":"11.4","Tissue RNA - parathyroid gland [nTPM]":"18.5","Tissue RNA - pituitary gland [nTPM]":"3.4","Tissue RNA - placenta [nTPM]":"13.2","Tissue RNA - pons [nTPM]":"8.2","Tissue RNA - prostate [nTPM]":"7.0","Tissue RNA - rectum [nTPM]":"21.9","Tissue RNA - retina [nTPM]":"6.4","Tissue RNA - salivary gland [nTPM]":"8.3","Tissue RNA - seminal vesicle [nTPM]":"8.8","Tissue RNA - skeletal muscle [nTPM]":"11.7","Tissue RNA - skin 1 [nTPM]":"4.5","Tissue RNA - small intestine [nTPM]":"13.1","Tissue RNA - smooth muscle [nTPM]":"21.1","Tissue RNA - spinal cord [nTPM]":"7.8","Tissue RNA - spleen [nTPM]":"8.7","Tissue RNA - stomach 1 [nTPM]":"9.9","Tissue RNA - testis [nTPM]":"16.3","Tissue RNA - thalamus [nTPM]":"6.3","Tissue RNA - thymus [nTPM]":"16.1","Tissue RNA - thyroid gland [nTPM]":"12.6","Tissue RNA - tongue [nTPM]":"12.6","Tissue RNA - tonsil [nTPM]":"12.8","Tissue RNA - urinary bladder [nTPM]":"14.6","Tissue RNA - vagina [nTPM]":"5.2","Tissue RNA - white matter [nTPM]":"11.9","Cell RNA - A-431 [nTPM]":"43.1","Cell RNA - A549 [nTPM]":"36.3","Cell RNA - AF22 [nTPM]":"23.3","Cell RNA - AN3-CA [nTPM]":"19.0","Cell RNA - ASC diff [nTPM]":"32.2","Cell RNA - ASC TERT1 [nTPM]":"33.2","Cell RNA - BEWO [nTPM]":"33.3","Cell RNA - BJ [nTPM]":"29.6","Cell RNA - BJ hTERT+ [nTPM]":"21.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"34.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"34.8","Cell RNA - CACO-2 [nTPM]":"70.6","Cell RNA - CAPAN-2 [nTPM]":"34.0","Cell RNA - Daudi [nTPM]":"58.5","Cell RNA - EFO-21 [nTPM]":"59.5","Cell RNA - fHDF\/TERT166 [nTPM]":"45.0","Cell RNA - GAMG [nTPM]":"46.3","Cell RNA - HaCaT [nTPM]":"47.5","Cell RNA - HAP1 [nTPM]":"64.4","Cell RNA - HBEC3-KT [nTPM]":"45.1","Cell RNA - HBF TERT88 [nTPM]":"47.8","Cell RNA - HDLM-2 [nTPM]":"51.4","Cell RNA - HEK 293 [nTPM]":"16.7","Cell RNA - HEL [nTPM]":"77.6","Cell RNA - HeLa [nTPM]":"56.5","Cell RNA - Hep G2 [nTPM]":"75.8","Cell RNA - HHSteC [nTPM]":"31.9","Cell RNA - HL-60 [nTPM]":"82.3","Cell RNA - HMC-1 [nTPM]":"63.5","Cell RNA - HSkMC [nTPM]":"28.6","Cell RNA - hTCEpi [nTPM]":"28.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"58.6","Cell RNA - hTERT-HME1 [nTPM]":"44.6","Cell RNA - hTERT-RPE1 [nTPM]":"33.3","Cell RNA - HUVEC TERT2 [nTPM]":"75.3","Cell RNA - JURKAT [nTPM]":"42.1","Cell RNA - K-562 [nTPM]":"44.9","Cell RNA - Karpas-707 [nTPM]":"26.3","Cell RNA - LHCN-M2 [nTPM]":"45.7","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"59.9","Cell RNA - NB-4 [nTPM]":"22.4","Cell RNA - NTERA-2 [nTPM]":"33.3","Cell RNA - OE19 [nTPM]":"42.7","Cell RNA - PC-3 [nTPM]":"30.9","Cell RNA - REH [nTPM]":"47.0","Cell RNA - RH-30 [nTPM]":"65.1","Cell RNA - RPMI-8226 [nTPM]":"32.7","Cell RNA - RPTEC TERT1 [nTPM]":"60.0","Cell RNA - RT4 [nTPM]":"65.0","Cell RNA - SCLC-21H [nTPM]":"22.0","Cell RNA - SH-SY5Y [nTPM]":"31.3","Cell RNA - SiHa [nTPM]":"66.2","Cell RNA - SK-BR-3 [nTPM]":"5.8","Cell RNA - SK-MEL-30 [nTPM]":"43.0","Cell RNA - SuSa [nTPM]":"58.1","Cell RNA - T-47d [nTPM]":"0.4","Cell RNA - THP-1 [nTPM]":"35.4","Cell RNA - TIME [nTPM]":"70.0","Cell RNA - U-138 MG [nTPM]":"29.4","Cell RNA - U-2 OS [nTPM]":"61.9","Cell RNA - U-2197 [nTPM]":"26.8","Cell RNA - U-251 MG [nTPM]":"64.2","Cell RNA - U-266\/70 [nTPM]":"28.7","Cell RNA - U-266\/84 [nTPM]":"59.0","Cell RNA - U-698 [nTPM]":"23.6","Cell RNA - U-87 MG [nTPM]":"29.4","Cell RNA - U-937 [nTPM]":"43.1","Cell RNA - WM-115 [nTPM]":"11.8","Blood RNA - basophil [nTPM]":"2.6","Blood RNA - classical monocyte [nTPM]":"3.3","Blood RNA - eosinophil [nTPM]":"5.8","Blood RNA - gdT-cell [nTPM]":"1.9","Blood RNA - intermediate monocyte [nTPM]":"4.0","Blood RNA - MAIT T-cell [nTPM]":"2.9","Blood RNA - memory B-cell [nTPM]":"1.7","Blood RNA - memory CD4 T-cell [nTPM]":"3.0","Blood RNA - memory CD8 T-cell [nTPM]":"2.4","Blood RNA - myeloid DC [nTPM]":"3.6","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"2.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.6","Blood RNA - neutrophil [nTPM]":"1.5","Blood RNA - NK-cell [nTPM]":"2.8","Blood RNA - non-classical monocyte [nTPM]":"3.6","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"4.3","Blood RNA - total PBMC [nTPM]":"2.2","Brain RNA - amygdala [nTPM]":"4.4","Brain RNA - basal ganglia [nTPM]":"6.9","Brain RNA - cerebellum [nTPM]":"7.1","Brain RNA - cerebral cortex [nTPM]":"6.9","Brain RNA - hippocampal formation [nTPM]":"4.7","Brain RNA - hypothalamus [nTPM]":"6.6","Brain RNA - medulla oblongata [nTPM]":"8.9","Brain RNA - midbrain [nTPM]":"7.0","Brain RNA - pons [nTPM]":"8.2","Brain RNA - spinal cord [nTPM]":"7.8","Brain RNA - thalamus [nTPM]":"6.3","Brain RNA - white matter [nTPM]":"11.9","Single Cell Type RNA - Adipocytes [nTPM]":"20.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.1","Single Cell Type RNA - Astrocytes [nTPM]":"29.4","Single Cell Type RNA - B-cells [nTPM]":"10.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.0","Single Cell Type RNA - Bipolar cells [nTPM]":"11.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"20.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"13.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.1","Single Cell Type RNA - dendritic cells [nTPM]":"15.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"25.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"20.9","Single Cell Type RNA - Early spermatids [nTPM]":"262.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.2","Single Cell Type RNA - Endothelial cells [nTPM]":"14.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.8","Single Cell Type RNA - Erythroid cells [nTPM]":"20.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"53.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.6","Single Cell Type RNA - Fibroblasts [nTPM]":"23.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.4","Single Cell Type RNA - granulocytes [nTPM]":"64.1","Single Cell Type RNA - Granulosa cells [nTPM]":"16.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"31.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"31.8","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"61.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"30.4","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"30.0","Single Cell Type RNA - Langerhans cells [nTPM]":"31.8","Single Cell Type RNA - Late spermatids [nTPM]":"41.4","Single Cell Type RNA - Leydig cells [nTPM]":"14.6","Single Cell Type RNA - Macrophages [nTPM]":"28.7","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"56.2","Single Cell Type RNA - monocytes [nTPM]":"36.0","Single Cell Type RNA - Muller glia cells [nTPM]":"12.0","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"45.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"83.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"23.9","Single Cell Type RNA - Paneth cells [nTPM]":"17.4","Single Cell Type RNA - Peritubular cells [nTPM]":"13.9","Single Cell Type RNA - Plasma cells [nTPM]":"14.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"46.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.4","Single Cell Type RNA - Spermatocytes [nTPM]":"41.7","Single Cell Type RNA - Spermatogonia [nTPM]":"22.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.0","Single Cell Type RNA - T-cells [nTPM]":"19.0","Single Cell Type RNA - Theca cells [nTPM]":"22.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.0","Single Cell Type RNA - Urothelial cells [nTPM]":"6.1"},{"Gene":"AGRN","Gene synonym":["AGRIN"],"Ensembl":"ENSG00000188157","Gene description":"Agrin","Uniprot":["O00468"],"Chromosome":"1","Position":"1020120-1056118","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins","Transporters"],"Biological process":["Differentiation"],"Molecular function":["Developmental protein"],"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"94.5","Collecting duct cells":"156.3","Ductal cells":"91.2","Pancreatic endocrine cells":"87.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"205.3","EFO-21":"236.9","HaCaT":"210.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040090"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"20000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA040090":"AB_10805603"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.62e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.4","Tissue RNA - adrenal gland [nTPM]":"2.7","Tissue RNA - amygdala [nTPM]":"8.7","Tissue RNA - appendix [nTPM]":"4.3","Tissue RNA - basal ganglia [nTPM]":"5.5","Tissue RNA - bone marrow [nTPM]":"2.0","Tissue RNA - breast [nTPM]":"14.7","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"13.9","Tissue RNA - cervix [nTPM]":"14.4","Tissue RNA - choroid plexus [nTPM]":"8.9","Tissue RNA - colon [nTPM]":"10.9","Tissue RNA - duodenum [nTPM]":"7.9","Tissue RNA - endometrium 1 [nTPM]":"13.7","Tissue RNA - epididymis [nTPM]":"1.8","Tissue RNA - esophagus [nTPM]":"15.6","Tissue RNA - fallopian tube [nTPM]":"14.6","Tissue RNA - gallbladder [nTPM]":"7.3","Tissue RNA - heart muscle [nTPM]":"9.9","Tissue RNA - hippocampal formation [nTPM]":"5.8","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"44.0","Tissue RNA - liver [nTPM]":"13.3","Tissue RNA - lung [nTPM]":"19.8","Tissue RNA - lymph node [nTPM]":"1.6","Tissue RNA - medulla oblongata [nTPM]":"16.0","Tissue RNA - midbrain [nTPM]":"1.4","Tissue RNA - ovary [nTPM]":"5.5","Tissue RNA - pancreas [nTPM]":"28.0","Tissue RNA - parathyroid gland [nTPM]":"3.9","Tissue RNA - pituitary gland [nTPM]":"8.3","Tissue RNA - placenta [nTPM]":"5.1","Tissue RNA - pons [nTPM]":"6.1","Tissue RNA - prostate [nTPM]":"14.4","Tissue RNA - rectum [nTPM]":"1.5","Tissue RNA - retina [nTPM]":"0.8","Tissue RNA - salivary gland [nTPM]":"24.8","Tissue RNA - seminal vesicle [nTPM]":"8.2","Tissue RNA - skeletal muscle [nTPM]":"4.2","Tissue RNA - skin 1 [nTPM]":"16.5","Tissue RNA - small intestine [nTPM]":"9.6","Tissue RNA - smooth muscle [nTPM]":"2.9","Tissue RNA - spinal cord [nTPM]":"2.2","Tissue RNA - spleen [nTPM]":"6.3","Tissue RNA - stomach 1 [nTPM]":"13.4","Tissue RNA - testis [nTPM]":"9.7","Tissue RNA - thalamus [nTPM]":"7.9","Tissue RNA - thymus [nTPM]":"2.6","Tissue RNA - thyroid gland [nTPM]":"34.7","Tissue RNA - tongue [nTPM]":"2.0","Tissue RNA - tonsil [nTPM]":"1.6","Tissue RNA - urinary bladder [nTPM]":"16.2","Tissue RNA - vagina [nTPM]":"11.6","Tissue RNA - white matter [nTPM]":"9.9","Cell RNA - A-431 [nTPM]":"124.3","Cell RNA - A549 [nTPM]":"75.1","Cell RNA - AF22 [nTPM]":"11.1","Cell RNA - AN3-CA [nTPM]":"42.7","Cell RNA - ASC diff [nTPM]":"2.4","Cell RNA - ASC TERT1 [nTPM]":"3.0","Cell RNA - BEWO [nTPM]":"122.1","Cell RNA - BJ [nTPM]":"61.4","Cell RNA - BJ hTERT+ [nTPM]":"19.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"39.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.5","Cell RNA - CACO-2 [nTPM]":"60.6","Cell RNA - CAPAN-2 [nTPM]":"205.3","Cell RNA - Daudi [nTPM]":"2.3","Cell RNA - EFO-21 [nTPM]":"236.9","Cell RNA - fHDF\/TERT166 [nTPM]":"9.6","Cell RNA - GAMG [nTPM]":"19.3","Cell RNA - HaCaT [nTPM]":"210.1","Cell RNA - HAP1 [nTPM]":"4.1","Cell RNA - HBEC3-KT [nTPM]":"75.6","Cell RNA - HBF TERT88 [nTPM]":"4.7","Cell RNA - HDLM-2 [nTPM]":"4.4","Cell RNA - HEK 293 [nTPM]":"28.6","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"102.1","Cell RNA - Hep G2 [nTPM]":"54.2","Cell RNA - HHSteC [nTPM]":"17.1","Cell RNA - HL-60 [nTPM]":"1.8","Cell RNA - HMC-1 [nTPM]":"23.1","Cell RNA - HSkMC [nTPM]":"10.5","Cell RNA - hTCEpi [nTPM]":"32.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.6","Cell RNA - hTERT-HME1 [nTPM]":"27.7","Cell RNA - hTERT-RPE1 [nTPM]":"55.9","Cell RNA - HUVEC TERT2 [nTPM]":"7.2","Cell RNA - JURKAT [nTPM]":"1.7","Cell RNA - K-562 [nTPM]":"25.7","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"3.5","Cell RNA - MCF7 [nTPM]":"93.0","Cell RNA - MOLT-4 [nTPM]":"0.8","Cell RNA - NB-4 [nTPM]":"17.6","Cell RNA - NTERA-2 [nTPM]":"28.4","Cell RNA - OE19 [nTPM]":"39.7","Cell RNA - PC-3 [nTPM]":"54.5","Cell RNA - REH [nTPM]":"20.1","Cell RNA - RH-30 [nTPM]":"27.0","Cell RNA - RPMI-8226 [nTPM]":"18.5","Cell RNA - RPTEC TERT1 [nTPM]":"70.0","Cell RNA - RT4 [nTPM]":"51.4","Cell RNA - SCLC-21H [nTPM]":"2.4","Cell RNA - SH-SY5Y [nTPM]":"25.9","Cell RNA - SiHa [nTPM]":"124.8","Cell RNA - SK-BR-3 [nTPM]":"129.1","Cell RNA - SK-MEL-30 [nTPM]":"121.9","Cell RNA - SuSa [nTPM]":"12.7","Cell RNA - T-47d [nTPM]":"114.8","Cell RNA - THP-1 [nTPM]":"7.4","Cell RNA - TIME [nTPM]":"107.8","Cell RNA - U-138 MG [nTPM]":"47.7","Cell RNA - U-2 OS [nTPM]":"169.0","Cell RNA - U-2197 [nTPM]":"6.4","Cell RNA - U-251 MG [nTPM]":"50.6","Cell RNA - U-266\/70 [nTPM]":"1.2","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"3.5","Cell RNA - U-87 MG [nTPM]":"30.4","Cell RNA - U-937 [nTPM]":"10.8","Cell RNA - WM-115 [nTPM]":"13.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"8.7","Brain RNA - basal ganglia [nTPM]":"5.5","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"13.9","Brain RNA - hippocampal formation [nTPM]":"5.8","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"16.0","Brain RNA - midbrain [nTPM]":"1.4","Brain RNA - pons [nTPM]":"6.1","Brain RNA - spinal cord [nTPM]":"2.2","Brain RNA - thalamus [nTPM]":"7.9","Brain RNA - white matter [nTPM]":"9.9","Single Cell Type RNA - Adipocytes [nTPM]":"27.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.8","Single Cell Type RNA - Astrocytes [nTPM]":"15.0","Single Cell Type RNA - B-cells [nTPM]":"2.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"94.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.9","Single Cell Type RNA - Bipolar cells [nTPM]":"1.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"32.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"39.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"61.5","Single Cell Type RNA - Club cells [nTPM]":"42.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"156.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"29.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"91.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"37.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.0","Single Cell Type RNA - Endothelial cells [nTPM]":"29.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.8","Single Cell Type RNA - Fibroblasts [nTPM]":"8.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"62.7","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"7.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.8","Single Cell Type RNA - Hepatocytes [nTPM]":"13.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.1","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.6","Single Cell Type RNA - Ionocytes [nTPM]":"36.7","Single Cell Type RNA - Kupffer cells [nTPM]":"2.9","Single Cell Type RNA - Langerhans cells [nTPM]":"10.1","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"5.6","Single Cell Type RNA - Macrophages [nTPM]":"4.3","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"15.6","Single Cell Type RNA - Muller glia cells [nTPM]":"10.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"29.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"87.3","Single Cell Type RNA - Paneth cells [nTPM]":"17.7","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"0.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"22.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"11.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - T-cells [nTPM]":"2.9","Single Cell Type RNA - Theca cells [nTPM]":"2.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.3","Single Cell Type RNA - Urothelial cells [nTPM]":"21.2"},{"Gene":"AGTPBP1","Gene synonym":["CCP1","KIAA1035","Nna1"],"Ensembl":"ENSG00000135049","Gene description":"ATP\/GTP binding protein 1","Uniprot":["Q9UPW5"],"Chromosome":"9","Position":"85546539-85742029","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Carboxypeptidase","Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"60.1","brain":"73.4","retina":"46.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"176.7","Inhibitory neurons":"163.0","Oligodendrocytes":"463.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057208","HPA071094"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoli","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA057208":"AB_2683370","HPA071094":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.60e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Tissue RNA - adipose tissue [nTPM]":"8.4","Tissue RNA - adrenal gland [nTPM]":"5.5","Tissue RNA - amygdala [nTPM]":"31.1","Tissue RNA - appendix [nTPM]":"9.5","Tissue RNA - basal ganglia [nTPM]":"44.3","Tissue RNA - bone marrow [nTPM]":"60.1","Tissue RNA - breast [nTPM]":"6.2","Tissue RNA - cerebellum [nTPM]":"23.2","Tissue RNA - cerebral cortex [nTPM]":"36.3","Tissue RNA - cervix [nTPM]":"4.7","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"5.1","Tissue RNA - duodenum [nTPM]":"3.7","Tissue RNA - endometrium 1 [nTPM]":"4.9","Tissue RNA - epididymis [nTPM]":"3.9","Tissue RNA - esophagus [nTPM]":"5.3","Tissue RNA - fallopian tube [nTPM]":"4.6","Tissue RNA - gallbladder [nTPM]":"5.3","Tissue RNA - heart muscle [nTPM]":"12.2","Tissue RNA - hippocampal formation [nTPM]":"20.1","Tissue RNA - hypothalamus [nTPM]":"30.3","Tissue RNA - kidney [nTPM]":"6.9","Tissue RNA - liver [nTPM]":"4.6","Tissue RNA - lung [nTPM]":"14.4","Tissue RNA - lymph node [nTPM]":"9.4","Tissue RNA - medulla oblongata [nTPM]":"30.5","Tissue RNA - midbrain [nTPM]":"28.6","Tissue RNA - ovary [nTPM]":"3.6","Tissue RNA - pancreas [nTPM]":"6.7","Tissue RNA - parathyroid gland [nTPM]":"7.5","Tissue RNA - pituitary gland [nTPM]":"5.3","Tissue RNA - placenta [nTPM]":"6.1","Tissue RNA - pons [nTPM]":"31.5","Tissue RNA - prostate [nTPM]":"4.7","Tissue RNA - rectum [nTPM]":"5.8","Tissue RNA - retina [nTPM]":"46.5","Tissue RNA - salivary gland [nTPM]":"4.1","Tissue RNA - seminal vesicle [nTPM]":"3.0","Tissue RNA - skeletal muscle [nTPM]":"16.5","Tissue RNA - skin 1 [nTPM]":"6.2","Tissue RNA - small intestine [nTPM]":"5.1","Tissue RNA - smooth muscle [nTPM]":"6.5","Tissue RNA - spinal cord [nTPM]":"32.0","Tissue RNA - spleen [nTPM]":"14.8","Tissue RNA - stomach 1 [nTPM]":"5.5","Tissue RNA - testis [nTPM]":"14.1","Tissue RNA - thalamus [nTPM]":"34.3","Tissue RNA - thymus [nTPM]":"12.4","Tissue RNA - thyroid gland [nTPM]":"5.8","Tissue RNA - tongue [nTPM]":"20.5","Tissue RNA - tonsil [nTPM]":"8.4","Tissue RNA - urinary bladder [nTPM]":"5.7","Tissue RNA - vagina [nTPM]":"4.3","Tissue RNA - white matter [nTPM]":"73.4","Cell RNA - A-431 [nTPM]":"5.1","Cell RNA - A549 [nTPM]":"9.6","Cell RNA - AF22 [nTPM]":"27.9","Cell RNA - AN3-CA [nTPM]":"11.1","Cell RNA - ASC diff [nTPM]":"5.6","Cell RNA - ASC TERT1 [nTPM]":"6.0","Cell RNA - BEWO [nTPM]":"10.6","Cell RNA - BJ [nTPM]":"7.4","Cell RNA - BJ hTERT+ [nTPM]":"6.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.4","Cell RNA - CACO-2 [nTPM]":"5.2","Cell RNA - CAPAN-2 [nTPM]":"8.6","Cell RNA - Daudi [nTPM]":"31.3","Cell RNA - EFO-21 [nTPM]":"6.2","Cell RNA - fHDF\/TERT166 [nTPM]":"7.7","Cell RNA - GAMG [nTPM]":"13.2","Cell RNA - HaCaT [nTPM]":"2.9","Cell RNA - HAP1 [nTPM]":"13.0","Cell RNA - HBEC3-KT [nTPM]":"9.4","Cell RNA - HBF TERT88 [nTPM]":"6.9","Cell RNA - HDLM-2 [nTPM]":"33.6","Cell RNA - HEK 293 [nTPM]":"11.8","Cell RNA - HEL [nTPM]":"5.3","Cell RNA - HeLa [nTPM]":"11.5","Cell RNA - Hep G2 [nTPM]":"9.3","Cell RNA - HHSteC [nTPM]":"11.8","Cell RNA - HL-60 [nTPM]":"24.5","Cell RNA - HMC-1 [nTPM]":"6.2","Cell RNA - HSkMC [nTPM]":"5.8","Cell RNA - hTCEpi [nTPM]":"10.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.0","Cell RNA - hTERT-HME1 [nTPM]":"23.5","Cell RNA - hTERT-RPE1 [nTPM]":"4.8","Cell RNA - HUVEC TERT2 [nTPM]":"11.9","Cell RNA - JURKAT [nTPM]":"15.9","Cell RNA - K-562 [nTPM]":"6.7","Cell RNA - Karpas-707 [nTPM]":"24.5","Cell RNA - LHCN-M2 [nTPM]":"3.3","Cell RNA - MCF7 [nTPM]":"8.0","Cell RNA - MOLT-4 [nTPM]":"19.3","Cell RNA - NB-4 [nTPM]":"14.5","Cell RNA - NTERA-2 [nTPM]":"19.3","Cell RNA - OE19 [nTPM]":"18.1","Cell RNA - PC-3 [nTPM]":"6.8","Cell RNA - REH [nTPM]":"17.3","Cell RNA - RH-30 [nTPM]":"10.2","Cell RNA - RPMI-8226 [nTPM]":"9.8","Cell RNA - RPTEC TERT1 [nTPM]":"12.8","Cell RNA - RT4 [nTPM]":"5.4","Cell RNA - SCLC-21H [nTPM]":"33.5","Cell RNA - SH-SY5Y [nTPM]":"23.7","Cell RNA - SiHa [nTPM]":"8.4","Cell RNA - SK-BR-3 [nTPM]":"9.1","Cell RNA - SK-MEL-30 [nTPM]":"15.4","Cell RNA - SuSa [nTPM]":"26.1","Cell RNA - T-47d [nTPM]":"3.5","Cell RNA - THP-1 [nTPM]":"7.8","Cell RNA - TIME [nTPM]":"12.0","Cell RNA - U-138 MG [nTPM]":"4.8","Cell RNA - U-2 OS [nTPM]":"8.5","Cell RNA - U-2197 [nTPM]":"30.4","Cell RNA - U-251 MG [nTPM]":"8.9","Cell RNA - U-266\/70 [nTPM]":"16.7","Cell RNA - U-266\/84 [nTPM]":"14.8","Cell RNA - U-698 [nTPM]":"14.3","Cell RNA - U-87 MG [nTPM]":"10.1","Cell RNA - U-937 [nTPM]":"23.5","Cell RNA - WM-115 [nTPM]":"9.8","Blood RNA - basophil [nTPM]":"37.4","Blood RNA - classical monocyte [nTPM]":"14.4","Blood RNA - eosinophil [nTPM]":"12.7","Blood RNA - gdT-cell [nTPM]":"9.0","Blood RNA - intermediate monocyte [nTPM]":"8.4","Blood RNA - MAIT T-cell [nTPM]":"8.8","Blood RNA - memory B-cell [nTPM]":"2.3","Blood RNA - memory CD4 T-cell [nTPM]":"4.4","Blood RNA - memory CD8 T-cell [nTPM]":"7.0","Blood RNA - myeloid DC [nTPM]":"15.6","Blood RNA - naive B-cell [nTPM]":"1.7","Blood RNA - naive CD4 T-cell [nTPM]":"3.7","Blood RNA - naive CD8 T-cell [nTPM]":"7.0","Blood RNA - neutrophil [nTPM]":"21.2","Blood RNA - NK-cell [nTPM]":"6.8","Blood RNA - non-classical monocyte [nTPM]":"6.7","Blood RNA - plasmacytoid DC [nTPM]":"2.5","Blood RNA - T-reg [nTPM]":"5.1","Blood RNA - total PBMC [nTPM]":"9.6","Brain RNA - amygdala [nTPM]":"31.1","Brain RNA - basal ganglia [nTPM]":"44.3","Brain RNA - cerebellum [nTPM]":"23.2","Brain RNA - cerebral cortex [nTPM]":"36.3","Brain RNA - hippocampal formation [nTPM]":"20.1","Brain RNA - hypothalamus [nTPM]":"30.3","Brain RNA - medulla oblongata [nTPM]":"30.5","Brain RNA - midbrain [nTPM]":"28.6","Brain RNA - pons [nTPM]":"31.5","Brain RNA - spinal cord [nTPM]":"32.0","Brain RNA - thalamus [nTPM]":"34.3","Brain RNA - white matter [nTPM]":"73.4","Single Cell Type RNA - Adipocytes [nTPM]":"22.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"64.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.8","Single Cell Type RNA - Astrocytes [nTPM]":"46.0","Single Cell Type RNA - B-cells [nTPM]":"14.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"38.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"48.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"13.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"102.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.1","Single Cell Type RNA - dendritic cells [nTPM]":"41.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.7","Single Cell Type RNA - Early spermatids [nTPM]":"52.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"29.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.6","Single Cell Type RNA - Endothelial cells [nTPM]":"12.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.7","Single Cell Type RNA - Erythroid cells [nTPM]":"16.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"176.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.3","Single Cell Type RNA - Fibroblasts [nTPM]":"6.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"22.0","Single Cell Type RNA - granulocytes [nTPM]":"27.1","Single Cell Type RNA - Granulosa cells [nTPM]":"9.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.2","Single Cell Type RNA - Hepatocytes [nTPM]":"3.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.1","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"163.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.6","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"35.4","Single Cell Type RNA - Langerhans cells [nTPM]":"24.1","Single Cell Type RNA - Late spermatids [nTPM]":"53.9","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"42.8","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"61.8","Single Cell Type RNA - monocytes [nTPM]":"46.6","Single Cell Type RNA - Muller glia cells [nTPM]":"16.7","Single Cell Type RNA - NK-cells [nTPM]":"47.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"82.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"463.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.1","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"26.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"59.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.4","Single Cell Type RNA - Spermatocytes [nTPM]":"46.6","Single Cell Type RNA - Spermatogonia [nTPM]":"29.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.9","Single Cell Type RNA - T-cells [nTPM]":"26.3","Single Cell Type RNA - Theca cells [nTPM]":"6.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.7","Single Cell Type RNA - Urothelial cells [nTPM]":"2.3"},{"Gene":"AGXT","Gene synonym":["AGT","AGT1","AGXT1","PH1","SPAT","SPT"],"Ensembl":"ENSG00000172482","Gene description":"Alanine--glyoxylate and serine--pyruvate aminotransferase","Uniprot":["P21549"],"Chromosome":"2","Position":"240868824-240880502","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Aminotransferase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"315","RNA tissue specific nTPM":{"liver":"2199.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Hepatocytes":"2037.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"425","RNA cancer specific FPKM":{"liver cancer":"253.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Hep G2":"5.2"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035370","HPA035371"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4700000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA035370":"AB_10673218","HPA035371":"AB_2674593"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.92e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"6.9","Tissue RNA - liver [nTPM]":"2199.2","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"2.2","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.7","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"5.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"1.2","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"6.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"44.3","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"2.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.0","Single Cell Type RNA - Erythroid cells [nTPM]":"128.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.7","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"52.5","Single Cell Type RNA - Hepatocytes [nTPM]":"2037.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.1","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"53.5","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"1.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"12.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"343.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - T-cells [nTPM]":"5.2","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"AHCY","Gene synonym":["SAHH"],"Ensembl":"ENSG00000101444","Gene description":"Adenosylhomocysteinase","Uniprot":["P23526"],"Chromosome":"20","Position":"34280268-34311802","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["One-carbon metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal tubular cells":"275.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041225","HPA044675"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5000000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA041225":"AB_2677371","HPA044675":"AB_2679041"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-3"},"Tissue RNA - adipose tissue [nTPM]":"44.9","Tissue RNA - adrenal gland [nTPM]":"56.7","Tissue RNA - amygdala [nTPM]":"38.5","Tissue RNA - appendix [nTPM]":"34.3","Tissue RNA - basal ganglia [nTPM]":"41.1","Tissue RNA - bone marrow [nTPM]":"59.3","Tissue RNA - breast [nTPM]":"71.0","Tissue RNA - cerebellum [nTPM]":"41.7","Tissue RNA - cerebral cortex [nTPM]":"40.1","Tissue RNA - cervix [nTPM]":"69.2","Tissue RNA - choroid plexus [nTPM]":"45.2","Tissue RNA - colon [nTPM]":"61.8","Tissue RNA - duodenum [nTPM]":"72.7","Tissue RNA - endometrium 1 [nTPM]":"55.8","Tissue RNA - epididymis [nTPM]":"65.7","Tissue RNA - esophagus [nTPM]":"140.9","Tissue RNA - fallopian tube [nTPM]":"75.8","Tissue RNA - gallbladder [nTPM]":"31.1","Tissue RNA - heart muscle [nTPM]":"67.1","Tissue RNA - hippocampal formation [nTPM]":"38.8","Tissue RNA - hypothalamus [nTPM]":"42.8","Tissue RNA - kidney [nTPM]":"155.5","Tissue RNA - liver [nTPM]":"187.4","Tissue RNA - lung [nTPM]":"41.5","Tissue RNA - lymph node [nTPM]":"45.4","Tissue RNA - medulla oblongata [nTPM]":"42.1","Tissue RNA - midbrain [nTPM]":"42.2","Tissue RNA - ovary [nTPM]":"116.4","Tissue RNA - pancreas [nTPM]":"161.5","Tissue RNA - parathyroid gland [nTPM]":"65.5","Tissue RNA - pituitary gland [nTPM]":"45.4","Tissue RNA - placenta [nTPM]":"39.5","Tissue RNA - pons [nTPM]":"43.3","Tissue RNA - prostate [nTPM]":"83.9","Tissue RNA - rectum [nTPM]":"58.0","Tissue RNA - retina [nTPM]":"24.6","Tissue RNA - salivary gland [nTPM]":"57.7","Tissue RNA - seminal vesicle [nTPM]":"49.6","Tissue RNA - skeletal muscle [nTPM]":"109.3","Tissue RNA - skin 1 [nTPM]":"50.9","Tissue RNA - small intestine [nTPM]":"54.8","Tissue RNA - smooth muscle [nTPM]":"43.6","Tissue RNA - spinal cord [nTPM]":"42.5","Tissue RNA - spleen [nTPM]":"39.9","Tissue RNA - stomach 1 [nTPM]":"75.8","Tissue RNA - testis [nTPM]":"82.0","Tissue RNA - thalamus [nTPM]":"42.5","Tissue RNA - thymus [nTPM]":"51.7","Tissue RNA - thyroid gland [nTPM]":"95.1","Tissue RNA - tongue [nTPM]":"63.6","Tissue RNA - tonsil [nTPM]":"55.9","Tissue RNA - urinary bladder [nTPM]":"59.3","Tissue RNA - vagina [nTPM]":"66.9","Tissue RNA - white matter [nTPM]":"44.6","Cell RNA - A-431 [nTPM]":"270.8","Cell RNA - A549 [nTPM]":"345.9","Cell RNA - AF22 [nTPM]":"143.6","Cell RNA - AN3-CA [nTPM]":"254.7","Cell RNA - ASC diff [nTPM]":"163.6","Cell RNA - ASC TERT1 [nTPM]":"174.8","Cell RNA - BEWO [nTPM]":"164.4","Cell RNA - BJ [nTPM]":"108.1","Cell RNA - BJ hTERT+ [nTPM]":"153.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"235.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"186.1","Cell RNA - CACO-2 [nTPM]":"942.0","Cell RNA - CAPAN-2 [nTPM]":"226.2","Cell RNA - Daudi [nTPM]":"417.0","Cell RNA - EFO-21 [nTPM]":"188.0","Cell RNA - fHDF\/TERT166 [nTPM]":"139.4","Cell RNA - GAMG [nTPM]":"152.0","Cell RNA - HaCaT [nTPM]":"301.2","Cell RNA - HAP1 [nTPM]":"340.7","Cell RNA - HBEC3-KT [nTPM]":"606.4","Cell RNA - HBF TERT88 [nTPM]":"150.3","Cell RNA - HDLM-2 [nTPM]":"55.6","Cell RNA - HEK 293 [nTPM]":"207.6","Cell RNA - HEL [nTPM]":"503.9","Cell RNA - HeLa [nTPM]":"157.3","Cell RNA - Hep G2 [nTPM]":"612.7","Cell RNA - HHSteC [nTPM]":"175.5","Cell RNA - HL-60 [nTPM]":"238.1","Cell RNA - HMC-1 [nTPM]":"158.3","Cell RNA - HSkMC [nTPM]":"364.1","Cell RNA - hTCEpi [nTPM]":"271.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"146.9","Cell RNA - hTERT-HME1 [nTPM]":"233.8","Cell RNA - hTERT-RPE1 [nTPM]":"125.9","Cell RNA - HUVEC TERT2 [nTPM]":"162.9","Cell RNA - JURKAT [nTPM]":"152.0","Cell RNA - K-562 [nTPM]":"250.1","Cell RNA - Karpas-707 [nTPM]":"102.7","Cell RNA - LHCN-M2 [nTPM]":"126.8","Cell RNA - MCF7 [nTPM]":"285.2","Cell RNA - MOLT-4 [nTPM]":"313.3","Cell RNA - NB-4 [nTPM]":"224.2","Cell RNA - NTERA-2 [nTPM]":"185.0","Cell RNA - OE19 [nTPM]":"343.0","Cell RNA - PC-3 [nTPM]":"332.7","Cell RNA - REH [nTPM]":"231.8","Cell RNA - RH-30 [nTPM]":"364.6","Cell RNA - RPMI-8226 [nTPM]":"294.1","Cell RNA - RPTEC TERT1 [nTPM]":"212.7","Cell RNA - RT4 [nTPM]":"188.3","Cell RNA - SCLC-21H [nTPM]":"247.8","Cell RNA - SH-SY5Y [nTPM]":"164.8","Cell RNA - SiHa [nTPM]":"216.1","Cell RNA - SK-BR-3 [nTPM]":"252.6","Cell RNA - SK-MEL-30 [nTPM]":"364.5","Cell RNA - SuSa [nTPM]":"112.8","Cell RNA - T-47d [nTPM]":"380.3","Cell RNA - THP-1 [nTPM]":"217.9","Cell RNA - TIME [nTPM]":"104.5","Cell RNA - U-138 MG [nTPM]":"203.3","Cell RNA - U-2 OS [nTPM]":"215.5","Cell RNA - U-2197 [nTPM]":"104.1","Cell RNA - U-251 MG [nTPM]":"207.6","Cell RNA - U-266\/70 [nTPM]":"151.7","Cell RNA - U-266\/84 [nTPM]":"239.0","Cell RNA - U-698 [nTPM]":"252.3","Cell RNA - U-87 MG [nTPM]":"150.2","Cell RNA - U-937 [nTPM]":"144.4","Cell RNA - WM-115 [nTPM]":"111.3","Blood RNA - basophil [nTPM]":"9.0","Blood RNA - classical monocyte [nTPM]":"32.9","Blood RNA - eosinophil [nTPM]":"1.0","Blood RNA - gdT-cell [nTPM]":"8.9","Blood RNA - intermediate monocyte [nTPM]":"60.7","Blood RNA - MAIT T-cell [nTPM]":"15.0","Blood RNA - memory B-cell [nTPM]":"20.5","Blood RNA - memory CD4 T-cell [nTPM]":"13.0","Blood RNA - memory CD8 T-cell [nTPM]":"11.5","Blood RNA - myeloid DC [nTPM]":"48.8","Blood RNA - naive B-cell [nTPM]":"19.4","Blood RNA - naive CD4 T-cell [nTPM]":"13.8","Blood RNA - naive CD8 T-cell [nTPM]":"16.1","Blood RNA - neutrophil [nTPM]":"2.7","Blood RNA - NK-cell [nTPM]":"11.6","Blood RNA - non-classical monocyte [nTPM]":"40.8","Blood RNA - plasmacytoid DC [nTPM]":"55.1","Blood RNA - T-reg [nTPM]":"16.4","Blood RNA - total PBMC [nTPM]":"28.2","Brain RNA - amygdala [nTPM]":"38.5","Brain RNA - basal ganglia [nTPM]":"41.1","Brain RNA - cerebellum [nTPM]":"41.7","Brain RNA - cerebral cortex [nTPM]":"40.1","Brain RNA - hippocampal formation [nTPM]":"38.8","Brain RNA - hypothalamus [nTPM]":"42.8","Brain RNA - medulla oblongata [nTPM]":"42.1","Brain RNA - midbrain [nTPM]":"42.2","Brain RNA - pons [nTPM]":"43.3","Brain RNA - spinal cord [nTPM]":"42.5","Brain RNA - thalamus [nTPM]":"42.5","Brain RNA - white matter [nTPM]":"44.6","Single Cell Type RNA - Adipocytes [nTPM]":"13.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.2","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"35.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"36.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"88.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"106.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"68.9","Single Cell Type RNA - Bipolar cells [nTPM]":"11.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"77.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"82.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"47.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"44.3","Single Cell Type RNA - Club cells [nTPM]":"43.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"109.0","Single Cell Type RNA - dendritic cells [nTPM]":"31.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"36.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"58.7","Single Cell Type RNA - Ductal cells [nTPM]":"73.5","Single Cell Type RNA - Early spermatids [nTPM]":"76.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"30.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"110.6","Single Cell Type RNA - Endothelial cells [nTPM]":"27.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.0","Single Cell Type RNA - Erythroid cells [nTPM]":"60.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"82.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"165.3","Single Cell Type RNA - Fibroblasts [nTPM]":"35.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"83.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"42.8","Single Cell Type RNA - granulocytes [nTPM]":"21.0","Single Cell Type RNA - Granulosa cells [nTPM]":"42.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.6","Single Cell Type RNA - Hepatocytes [nTPM]":"70.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"115.7","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"73.5","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"52.2","Single Cell Type RNA - Langerhans cells [nTPM]":"32.4","Single Cell Type RNA - Late spermatids [nTPM]":"187.4","Single Cell Type RNA - Leydig cells [nTPM]":"42.6","Single Cell Type RNA - Macrophages [nTPM]":"34.5","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"26.4","Single Cell Type RNA - Muller glia cells [nTPM]":"42.4","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"60.4","Single Cell Type RNA - Paneth cells [nTPM]":"41.2","Single Cell Type RNA - Peritubular cells [nTPM]":"40.6","Single Cell Type RNA - Plasma cells [nTPM]":"66.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"95.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"51.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"275.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"34.6","Single Cell Type RNA - Spermatocytes [nTPM]":"43.5","Single Cell Type RNA - Spermatogonia [nTPM]":"45.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"100.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"39.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"91.9","Single Cell Type RNA - T-cells [nTPM]":"19.8","Single Cell Type RNA - Theca cells [nTPM]":"84.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"117.1","Single Cell Type RNA - Urothelial cells [nTPM]":"82.6"},{"Gene":"AICDA","Gene synonym":["AID","ARP2","CDA2","HIGM2"],"Ensembl":"ENSG00000111732","Gene description":"Activation induced cytidine deaminase","Uniprot":["Q9GZX7"],"Chromosome":"12","Position":"8602170-8612867","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["mRNA processing"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"lymphoid tissue":"15.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"2.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"0.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"memory B-cell":"1.9","naive B-cell":"3.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"B-cells":"3.8"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Daudi":"142.5","U-698":"118.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"3.7","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"1.2","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"15.4","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"1.4","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.8","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.7","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"12.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"142.5","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"5.3","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"2.0","Cell RNA - HMC-1 [nTPM]":"19.8","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.5","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"1.3","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.6","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"118.4","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"1.9","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"3.8","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"1.2","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"0.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"AK1","Gene synonym":[],"Ensembl":"ENSG00000106992","Gene description":"Adenylate kinase 1","Uniprot":["P00568"],"Chromosome":"9","Position":"127866486-127877675","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant","Hereditary hemolytic anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"1346.2","tongue":"783.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"281.3","Late spermatids":"1031.8","Muller glia cells":"287.6","Peritubular cells":"386.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-2197":"163.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006456","CAB009893"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"24000000","Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB009893":"AB_2225151","HPA006456":"AB_1078116"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.31e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.40e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-3"},"Tissue RNA - adipose tissue [nTPM]":"28.5","Tissue RNA - adrenal gland [nTPM]":"34.5","Tissue RNA - amygdala [nTPM]":"81.3","Tissue RNA - appendix [nTPM]":"11.5","Tissue RNA - basal ganglia [nTPM]":"79.2","Tissue RNA - bone marrow [nTPM]":"28.4","Tissue RNA - breast [nTPM]":"17.0","Tissue RNA - cerebellum [nTPM]":"87.9","Tissue RNA - cerebral cortex [nTPM]":"95.1","Tissue RNA - cervix [nTPM]":"37.5","Tissue RNA - choroid plexus [nTPM]":"145.8","Tissue RNA - colon [nTPM]":"33.8","Tissue RNA - duodenum [nTPM]":"17.9","Tissue RNA - endometrium 1 [nTPM]":"14.3","Tissue RNA - epididymis [nTPM]":"28.5","Tissue RNA - esophagus [nTPM]":"32.0","Tissue RNA - fallopian tube [nTPM]":"342.2","Tissue RNA - gallbladder [nTPM]":"22.5","Tissue RNA - heart muscle [nTPM]":"270.0","Tissue RNA - hippocampal formation [nTPM]":"79.5","Tissue RNA - hypothalamus [nTPM]":"88.5","Tissue RNA - kidney [nTPM]":"31.4","Tissue RNA - liver [nTPM]":"26.5","Tissue RNA - lung [nTPM]":"74.6","Tissue RNA - lymph node [nTPM]":"5.0","Tissue RNA - medulla oblongata [nTPM]":"97.4","Tissue RNA - midbrain [nTPM]":"99.8","Tissue RNA - ovary [nTPM]":"45.0","Tissue RNA - pancreas [nTPM]":"14.9","Tissue RNA - parathyroid gland [nTPM]":"47.0","Tissue RNA - pituitary gland [nTPM]":"33.8","Tissue RNA - placenta [nTPM]":"7.6","Tissue RNA - pons [nTPM]":"99.0","Tissue RNA - prostate [nTPM]":"17.1","Tissue RNA - rectum [nTPM]":"39.5","Tissue RNA - retina [nTPM]":"29.0","Tissue RNA - salivary gland [nTPM]":"33.1","Tissue RNA - seminal vesicle [nTPM]":"35.9","Tissue RNA - skeletal muscle [nTPM]":"1346.2","Tissue RNA - skin 1 [nTPM]":"14.2","Tissue RNA - small intestine [nTPM]":"12.1","Tissue RNA - smooth muscle [nTPM]":"21.9","Tissue RNA - spinal cord [nTPM]":"105.0","Tissue RNA - spleen [nTPM]":"20.8","Tissue RNA - stomach 1 [nTPM]":"23.9","Tissue RNA - testis [nTPM]":"63.1","Tissue RNA - thalamus [nTPM]":"89.4","Tissue RNA - thymus [nTPM]":"3.9","Tissue RNA - thyroid gland [nTPM]":"34.8","Tissue RNA - tongue [nTPM]":"783.3","Tissue RNA - tonsil [nTPM]":"12.6","Tissue RNA - urinary bladder [nTPM]":"19.7","Tissue RNA - vagina [nTPM]":"19.4","Tissue RNA - white matter [nTPM]":"97.2","Cell RNA - A-431 [nTPM]":"56.7","Cell RNA - A549 [nTPM]":"23.6","Cell RNA - AF22 [nTPM]":"30.1","Cell RNA - AN3-CA [nTPM]":"40.4","Cell RNA - ASC diff [nTPM]":"71.2","Cell RNA - ASC TERT1 [nTPM]":"142.9","Cell RNA - BEWO [nTPM]":"27.4","Cell RNA - BJ [nTPM]":"38.3","Cell RNA - BJ hTERT+ [nTPM]":"38.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"66.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"40.4","Cell RNA - CACO-2 [nTPM]":"18.0","Cell RNA - CAPAN-2 [nTPM]":"34.9","Cell RNA - Daudi [nTPM]":"1.5","Cell RNA - EFO-21 [nTPM]":"40.8","Cell RNA - fHDF\/TERT166 [nTPM]":"79.4","Cell RNA - GAMG [nTPM]":"44.1","Cell RNA - HaCaT [nTPM]":"79.2","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"43.1","Cell RNA - HBF TERT88 [nTPM]":"26.6","Cell RNA - HDLM-2 [nTPM]":"9.0","Cell RNA - HEK 293 [nTPM]":"26.1","Cell RNA - HEL [nTPM]":"8.3","Cell RNA - HeLa [nTPM]":"65.2","Cell RNA - Hep G2 [nTPM]":"31.6","Cell RNA - HHSteC [nTPM]":"40.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.0","Cell RNA - HSkMC [nTPM]":"110.9","Cell RNA - hTCEpi [nTPM]":"81.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"49.9","Cell RNA - hTERT-HME1 [nTPM]":"35.5","Cell RNA - hTERT-RPE1 [nTPM]":"36.8","Cell RNA - HUVEC TERT2 [nTPM]":"90.3","Cell RNA - JURKAT [nTPM]":"0.8","Cell RNA - K-562 [nTPM]":"33.7","Cell RNA - Karpas-707 [nTPM]":"2.3","Cell RNA - LHCN-M2 [nTPM]":"76.7","Cell RNA - MCF7 [nTPM]":"53.5","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"1.1","Cell RNA - NTERA-2 [nTPM]":"10.6","Cell RNA - OE19 [nTPM]":"139.7","Cell RNA - PC-3 [nTPM]":"74.2","Cell RNA - REH [nTPM]":"1.3","Cell RNA - RH-30 [nTPM]":"30.0","Cell RNA - RPMI-8226 [nTPM]":"12.6","Cell RNA - RPTEC TERT1 [nTPM]":"44.8","Cell RNA - RT4 [nTPM]":"4.1","Cell RNA - SCLC-21H [nTPM]":"48.3","Cell RNA - SH-SY5Y [nTPM]":"30.4","Cell RNA - SiHa [nTPM]":"101.0","Cell RNA - SK-BR-3 [nTPM]":"57.4","Cell RNA - SK-MEL-30 [nTPM]":"29.8","Cell RNA - SuSa [nTPM]":"15.3","Cell RNA - T-47d [nTPM]":"45.8","Cell RNA - THP-1 [nTPM]":"33.3","Cell RNA - TIME [nTPM]":"75.9","Cell RNA - U-138 MG [nTPM]":"45.9","Cell RNA - U-2 OS [nTPM]":"18.8","Cell RNA - U-2197 [nTPM]":"163.8","Cell RNA - U-251 MG [nTPM]":"37.3","Cell RNA - U-266\/70 [nTPM]":"3.5","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"57.7","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"32.4","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"81.3","Brain RNA - basal ganglia [nTPM]":"79.2","Brain RNA - cerebellum [nTPM]":"87.9","Brain RNA - cerebral cortex [nTPM]":"95.1","Brain RNA - hippocampal formation [nTPM]":"79.5","Brain RNA - hypothalamus [nTPM]":"88.5","Brain RNA - medulla oblongata [nTPM]":"97.4","Brain RNA - midbrain [nTPM]":"99.8","Brain RNA - pons [nTPM]":"99.0","Brain RNA - spinal cord [nTPM]":"105.0","Brain RNA - thalamus [nTPM]":"89.4","Brain RNA - white matter [nTPM]":"97.2","Single Cell Type RNA - Adipocytes [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"148.1","Single Cell Type RNA - Astrocytes [nTPM]":"25.8","Single Cell Type RNA - B-cells [nTPM]":"2.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"26.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"84.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"54.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"49.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"28.6","Single Cell Type RNA - Club cells [nTPM]":"79.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.5","Single Cell Type RNA - dendritic cells [nTPM]":"5.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"210.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"116.7","Single Cell Type RNA - Early spermatids [nTPM]":"281.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.0","Single Cell Type RNA - Endothelial cells [nTPM]":"39.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"106.3","Single Cell Type RNA - Erythroid cells [nTPM]":"97.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"60.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"46.8","Single Cell Type RNA - Fibroblasts [nTPM]":"37.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"46.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.8","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"2.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"49.2","Single Cell Type RNA - Hepatocytes [nTPM]":"77.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"59.3","Single Cell Type RNA - Horizontal cells [nTPM]":"48.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"62.7","Single Cell Type RNA - Ionocytes [nTPM]":"120.1","Single Cell Type RNA - Kupffer cells [nTPM]":"3.7","Single Cell Type RNA - Langerhans cells [nTPM]":"22.3","Single Cell Type RNA - Late spermatids [nTPM]":"1031.8","Single Cell Type RNA - Leydig cells [nTPM]":"226.5","Single Cell Type RNA - Macrophages [nTPM]":"7.9","Single Cell Type RNA - Melanocytes [nTPM]":"83.6","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"2.3","Single Cell Type RNA - Muller glia cells [nTPM]":"287.6","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"57.2","Single Cell Type RNA - Paneth cells [nTPM]":"132.7","Single Cell Type RNA - Peritubular cells [nTPM]":"386.3","Single Cell Type RNA - Plasma cells [nTPM]":"4.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"186.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"69.5","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"107.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"56.4","Single Cell Type RNA - Spermatocytes [nTPM]":"20.2","Single Cell Type RNA - Spermatogonia [nTPM]":"16.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"33.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"28.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"13.5","Single Cell Type RNA - T-cells [nTPM]":"7.1","Single Cell Type RNA - Theca cells [nTPM]":"83.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"65.5","Single Cell Type RNA - Urothelial cells [nTPM]":"25.3"},{"Gene":"AK2","Gene synonym":[],"Ensembl":"ENSG00000004455","Gene description":"Adenylate kinase 2","Uniprot":["P54819"],"Chromosome":"1","Position":"33007940-33080996","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant","SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal tubular cells":"440.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018479","CAB079913"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1100000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB079913":"AB_2546087","HPA018479":"AB_1844676"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.37e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.65e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.32e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.40e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-3"},"Tissue RNA - adipose tissue [nTPM]":"85.3","Tissue RNA - adrenal gland [nTPM]":"88.6","Tissue RNA - amygdala [nTPM]":"39.9","Tissue RNA - appendix [nTPM]":"76.9","Tissue RNA - basal ganglia [nTPM]":"45.0","Tissue RNA - bone marrow [nTPM]":"74.3","Tissue RNA - breast [nTPM]":"80.4","Tissue RNA - cerebellum [nTPM]":"44.1","Tissue RNA - cerebral cortex [nTPM]":"49.0","Tissue RNA - cervix [nTPM]":"79.6","Tissue RNA - choroid plexus [nTPM]":"49.8","Tissue RNA - colon [nTPM]":"117.2","Tissue RNA - duodenum [nTPM]":"140.0","Tissue RNA - endometrium 1 [nTPM]":"58.6","Tissue RNA - epididymis [nTPM]":"52.1","Tissue RNA - esophagus [nTPM]":"108.5","Tissue RNA - fallopian tube [nTPM]":"65.3","Tissue RNA - gallbladder [nTPM]":"49.0","Tissue RNA - heart muscle [nTPM]":"114.1","Tissue RNA - hippocampal formation [nTPM]":"38.8","Tissue RNA - hypothalamus [nTPM]":"43.8","Tissue RNA - kidney [nTPM]":"181.6","Tissue RNA - liver [nTPM]":"172.9","Tissue RNA - lung [nTPM]":"59.3","Tissue RNA - lymph node [nTPM]":"73.3","Tissue RNA - medulla oblongata [nTPM]":"48.5","Tissue RNA - midbrain [nTPM]":"42.8","Tissue RNA - ovary [nTPM]":"59.9","Tissue RNA - pancreas [nTPM]":"78.9","Tissue RNA - parathyroid gland [nTPM]":"123.6","Tissue RNA - pituitary gland [nTPM]":"49.4","Tissue RNA - placenta [nTPM]":"68.4","Tissue RNA - pons [nTPM]":"50.4","Tissue RNA - prostate [nTPM]":"63.2","Tissue RNA - rectum [nTPM]":"114.0","Tissue RNA - retina [nTPM]":"51.0","Tissue RNA - salivary gland [nTPM]":"81.1","Tissue RNA - seminal vesicle [nTPM]":"55.5","Tissue RNA - skeletal muscle [nTPM]":"154.2","Tissue RNA - skin 1 [nTPM]":"74.4","Tissue RNA - small intestine [nTPM]":"139.4","Tissue RNA - smooth muscle [nTPM]":"68.1","Tissue RNA - spinal cord [nTPM]":"44.0","Tissue RNA - spleen [nTPM]":"57.2","Tissue RNA - stomach 1 [nTPM]":"92.7","Tissue RNA - testis [nTPM]":"54.8","Tissue RNA - thalamus [nTPM]":"44.3","Tissue RNA - thymus [nTPM]":"85.9","Tissue RNA - thyroid gland [nTPM]":"86.6","Tissue RNA - tongue [nTPM]":"122.9","Tissue RNA - tonsil [nTPM]":"113.4","Tissue RNA - urinary bladder [nTPM]":"84.2","Tissue RNA - vagina [nTPM]":"76.9","Tissue RNA - white matter [nTPM]":"49.3","Cell RNA - A-431 [nTPM]":"339.1","Cell RNA - A549 [nTPM]":"153.4","Cell RNA - AF22 [nTPM]":"131.6","Cell RNA - AN3-CA [nTPM]":"149.7","Cell RNA - ASC diff [nTPM]":"94.9","Cell RNA - ASC TERT1 [nTPM]":"116.6","Cell RNA - BEWO [nTPM]":"132.8","Cell RNA - BJ [nTPM]":"185.0","Cell RNA - BJ hTERT+ [nTPM]":"143.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"267.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"280.2","Cell RNA - CACO-2 [nTPM]":"283.2","Cell RNA - CAPAN-2 [nTPM]":"311.9","Cell RNA - Daudi [nTPM]":"602.1","Cell RNA - EFO-21 [nTPM]":"218.4","Cell RNA - fHDF\/TERT166 [nTPM]":"139.8","Cell RNA - GAMG [nTPM]":"204.2","Cell RNA - HaCaT [nTPM]":"235.4","Cell RNA - HAP1 [nTPM]":"312.5","Cell RNA - HBEC3-KT [nTPM]":"327.0","Cell RNA - HBF TERT88 [nTPM]":"276.6","Cell RNA - HDLM-2 [nTPM]":"261.6","Cell RNA - HEK 293 [nTPM]":"229.3","Cell RNA - HEL [nTPM]":"396.2","Cell RNA - HeLa [nTPM]":"270.0","Cell RNA - Hep G2 [nTPM]":"219.9","Cell RNA - HHSteC [nTPM]":"218.2","Cell RNA - HL-60 [nTPM]":"712.5","Cell RNA - HMC-1 [nTPM]":"222.2","Cell RNA - HSkMC [nTPM]":"118.1","Cell RNA - hTCEpi [nTPM]":"238.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"232.7","Cell RNA - hTERT-HME1 [nTPM]":"471.2","Cell RNA - hTERT-RPE1 [nTPM]":"163.3","Cell RNA - HUVEC TERT2 [nTPM]":"190.2","Cell RNA - JURKAT [nTPM]":"245.7","Cell RNA - K-562 [nTPM]":"436.9","Cell RNA - Karpas-707 [nTPM]":"230.4","Cell RNA - LHCN-M2 [nTPM]":"165.0","Cell RNA - MCF7 [nTPM]":"174.2","Cell RNA - MOLT-4 [nTPM]":"273.0","Cell RNA - NB-4 [nTPM]":"392.8","Cell RNA - NTERA-2 [nTPM]":"181.2","Cell RNA - OE19 [nTPM]":"337.4","Cell RNA - PC-3 [nTPM]":"222.4","Cell RNA - REH [nTPM]":"314.7","Cell RNA - RH-30 [nTPM]":"222.2","Cell RNA - RPMI-8226 [nTPM]":"415.6","Cell RNA - RPTEC TERT1 [nTPM]":"286.2","Cell RNA - RT4 [nTPM]":"205.1","Cell RNA - SCLC-21H [nTPM]":"190.8","Cell RNA - SH-SY5Y [nTPM]":"114.8","Cell RNA - SiHa [nTPM]":"205.4","Cell RNA - SK-BR-3 [nTPM]":"235.0","Cell RNA - SK-MEL-30 [nTPM]":"584.8","Cell RNA - SuSa [nTPM]":"151.4","Cell RNA - T-47d [nTPM]":"194.5","Cell RNA - THP-1 [nTPM]":"517.2","Cell RNA - TIME [nTPM]":"138.9","Cell RNA - U-138 MG [nTPM]":"165.5","Cell RNA - U-2 OS [nTPM]":"194.3","Cell RNA - U-2197 [nTPM]":"259.4","Cell RNA - U-251 MG [nTPM]":"357.5","Cell RNA - U-266\/70 [nTPM]":"238.0","Cell RNA - U-266\/84 [nTPM]":"324.7","Cell RNA - U-698 [nTPM]":"565.7","Cell RNA - U-87 MG [nTPM]":"232.4","Cell RNA - U-937 [nTPM]":"664.6","Cell RNA - WM-115 [nTPM]":"195.5","Blood RNA - basophil [nTPM]":"49.2","Blood RNA - classical monocyte [nTPM]":"158.8","Blood RNA - eosinophil [nTPM]":"198.0","Blood RNA - gdT-cell [nTPM]":"77.1","Blood RNA - intermediate monocyte [nTPM]":"145.5","Blood RNA - MAIT T-cell [nTPM]":"81.8","Blood RNA - memory B-cell [nTPM]":"122.3","Blood RNA - memory CD4 T-cell [nTPM]":"72.7","Blood RNA - memory CD8 T-cell [nTPM]":"74.0","Blood RNA - myeloid DC [nTPM]":"195.8","Blood RNA - naive B-cell [nTPM]":"105.8","Blood RNA - naive CD4 T-cell [nTPM]":"72.9","Blood RNA - naive CD8 T-cell [nTPM]":"67.9","Blood RNA - neutrophil [nTPM]":"42.1","Blood RNA - NK-cell [nTPM]":"115.3","Blood RNA - non-classical monocyte [nTPM]":"130.4","Blood RNA - plasmacytoid DC [nTPM]":"154.2","Blood RNA - T-reg [nTPM]":"96.8","Blood RNA - total PBMC [nTPM]":"188.1","Brain RNA - amygdala [nTPM]":"39.9","Brain RNA - basal ganglia [nTPM]":"45.0","Brain RNA - cerebellum [nTPM]":"44.1","Brain RNA - cerebral cortex [nTPM]":"49.0","Brain RNA - hippocampal formation [nTPM]":"38.8","Brain RNA - hypothalamus [nTPM]":"43.8","Brain RNA - medulla oblongata [nTPM]":"48.5","Brain RNA - midbrain [nTPM]":"42.8","Brain RNA - pons [nTPM]":"50.4","Brain RNA - spinal cord [nTPM]":"44.0","Brain RNA - thalamus [nTPM]":"44.3","Brain RNA - white matter [nTPM]":"49.3","Single Cell Type RNA - Adipocytes [nTPM]":"60.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"79.0","Single Cell Type RNA - Astrocytes [nTPM]":"19.6","Single Cell Type RNA - B-cells [nTPM]":"44.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"125.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"101.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"228.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"63.7","Single Cell Type RNA - Bipolar cells [nTPM]":"21.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"66.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"72.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"106.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"71.4","Single Cell Type RNA - Club cells [nTPM]":"142.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"112.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"83.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"158.0","Single Cell Type RNA - dendritic cells [nTPM]":"37.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"109.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"256.3","Single Cell Type RNA - Ductal cells [nTPM]":"120.2","Single Cell Type RNA - Early spermatids [nTPM]":"108.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"50.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"42.1","Single Cell Type RNA - Endothelial cells [nTPM]":"70.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"50.4","Single Cell Type RNA - Erythroid cells [nTPM]":"50.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"123.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"164.6","Single Cell Type RNA - Fibroblasts [nTPM]":"58.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"66.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"47.0","Single Cell Type RNA - granulocytes [nTPM]":"40.0","Single Cell Type RNA - Granulosa cells [nTPM]":"38.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"41.4","Single Cell Type RNA - Hepatocytes [nTPM]":"135.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"96.1","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"19.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"84.7","Single Cell Type RNA - Ionocytes [nTPM]":"89.5","Single Cell Type RNA - Kupffer cells [nTPM]":"44.8","Single Cell Type RNA - Langerhans cells [nTPM]":"60.1","Single Cell Type RNA - Late spermatids [nTPM]":"42.8","Single Cell Type RNA - Leydig cells [nTPM]":"46.9","Single Cell Type RNA - Macrophages [nTPM]":"48.4","Single Cell Type RNA - Melanocytes [nTPM]":"87.2","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"67.3","Single Cell Type RNA - Muller glia cells [nTPM]":"22.1","Single Cell Type RNA - NK-cells [nTPM]":"48.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"22.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"110.5","Single Cell Type RNA - Paneth cells [nTPM]":"67.2","Single Cell Type RNA - Peritubular cells [nTPM]":"44.0","Single Cell Type RNA - Plasma cells [nTPM]":"55.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"109.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"236.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"440.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"67.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"41.8","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"34.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"108.4","Single Cell Type RNA - Spermatocytes [nTPM]":"91.0","Single Cell Type RNA - Spermatogonia [nTPM]":"31.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"88.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"122.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"216.6","Single Cell Type RNA - T-cells [nTPM]":"40.7","Single Cell Type RNA - Theca cells [nTPM]":"72.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"122.6","Single Cell Type RNA - Urothelial cells [nTPM]":"120.5"},{"Gene":"AK7","Gene synonym":["CFAP75","FAP75","FLJ32864"],"Ensembl":"ENSG00000140057","Gene description":"Adenylate kinase 7","Uniprot":["Q96M32"],"Chromosome":"14","Position":"96392128-96489427","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"fallopian tube":"24.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Endometrial ciliated cells":"97.9","Respiratory ciliated cells":"137.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"23","RNA blood cell specific nTPM":{"basophil":"9.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"29","RNA blood lineage specific nTPM":{"granulocytes":"9.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"17.0","CAPAN-2":"15.1","MCF7":"49.5","REH":"35.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003543"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA003543":"AB_1078117"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.18e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.14e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.7","Tissue RNA - adrenal gland [nTPM]":"2.6","Tissue RNA - amygdala [nTPM]":"2.0","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"3.1","Tissue RNA - bone marrow [nTPM]":"1.5","Tissue RNA - breast [nTPM]":"1.4","Tissue RNA - cerebellum [nTPM]":"1.1","Tissue RNA - cerebral cortex [nTPM]":"1.7","Tissue RNA - cervix [nTPM]":"1.7","Tissue RNA - choroid plexus [nTPM]":"13.2","Tissue RNA - colon [nTPM]":"2.1","Tissue RNA - duodenum [nTPM]":"1.9","Tissue RNA - endometrium 1 [nTPM]":"2.1","Tissue RNA - epididymis [nTPM]":"3.9","Tissue RNA - esophagus [nTPM]":"1.5","Tissue RNA - fallopian tube [nTPM]":"24.3","Tissue RNA - gallbladder [nTPM]":"2.6","Tissue RNA - heart muscle [nTPM]":"0.7","Tissue RNA - hippocampal formation [nTPM]":"2.2","Tissue RNA - hypothalamus [nTPM]":"5.2","Tissue RNA - kidney [nTPM]":"4.5","Tissue RNA - liver [nTPM]":"1.6","Tissue RNA - lung [nTPM]":"4.2","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"6.9","Tissue RNA - midbrain [nTPM]":"9.4","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"2.2","Tissue RNA - parathyroid gland [nTPM]":"6.9","Tissue RNA - pituitary gland [nTPM]":"5.1","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"5.6","Tissue RNA - prostate [nTPM]":"0.9","Tissue RNA - rectum [nTPM]":"1.6","Tissue RNA - retina [nTPM]":"3.0","Tissue RNA - salivary gland [nTPM]":"1.0","Tissue RNA - seminal vesicle [nTPM]":"1.3","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"6.1","Tissue RNA - small intestine [nTPM]":"1.2","Tissue RNA - smooth muscle [nTPM]":"1.1","Tissue RNA - spinal cord [nTPM]":"4.4","Tissue RNA - spleen [nTPM]":"3.3","Tissue RNA - stomach 1 [nTPM]":"2.8","Tissue RNA - testis [nTPM]":"7.6","Tissue RNA - thalamus [nTPM]":"5.0","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"2.7","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"0.5","Tissue RNA - vagina [nTPM]":"1.0","Tissue RNA - white matter [nTPM]":"4.2","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"4.9","Cell RNA - AF22 [nTPM]":"2.0","Cell RNA - AN3-CA [nTPM]":"1.5","Cell RNA - ASC diff [nTPM]":"0.8","Cell RNA - ASC TERT1 [nTPM]":"2.6","Cell RNA - BEWO [nTPM]":"17.0","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"15.1","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"1.9","Cell RNA - HAP1 [nTPM]":"4.7","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"2.2","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"2.4","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.8","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.5","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.8","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"1.4","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.3","Cell RNA - MCF7 [nTPM]":"49.5","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"2.2","Cell RNA - PC-3 [nTPM]":"1.0","Cell RNA - REH [nTPM]":"35.2","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"7.6","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"3.1","Cell RNA - SH-SY5Y [nTPM]":"6.7","Cell RNA - SiHa [nTPM]":"1.9","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"1.8","Cell RNA - T-47d [nTPM]":"4.2","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.4","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.6","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.6","Cell RNA - U-266\/84 [nTPM]":"2.3","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.7","Blood RNA - basophil [nTPM]":"9.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"2.0","Brain RNA - basal ganglia [nTPM]":"3.1","Brain RNA - cerebellum [nTPM]":"1.1","Brain RNA - cerebral cortex [nTPM]":"1.7","Brain RNA - hippocampal formation [nTPM]":"2.2","Brain RNA - hypothalamus [nTPM]":"5.2","Brain RNA - medulla oblongata [nTPM]":"6.9","Brain RNA - midbrain [nTPM]":"9.4","Brain RNA - pons [nTPM]":"5.6","Brain RNA - spinal cord [nTPM]":"4.4","Brain RNA - thalamus [nTPM]":"5.0","Brain RNA - white matter [nTPM]":"4.2","Single Cell Type RNA - Adipocytes [nTPM]":"1.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"12.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.2","Single Cell Type RNA - Early spermatids [nTPM]":"18.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"97.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.7","Single Cell Type RNA - Endothelial cells [nTPM]":"1.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"6.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.7","Single Cell Type RNA - Fibroblasts [nTPM]":"0.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"2.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"4.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"137.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.6","Single Cell Type RNA - Spermatocytes [nTPM]":"25.4","Single Cell Type RNA - Spermatogonia [nTPM]":"9.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.9","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"1.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"AKR1C4","Gene synonym":["3-alpha-HSD","C11","CDR","CHDR","DD4","HAKRA","MGC22581"],"Ensembl":"ENSG00000198610","Gene description":"Aldo-keto reductase family 1 member C4","Uniprot":["P17516"],"Chromosome":"10","Position":"5195462-5218949","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"17","RNA tissue specific nTPM":{"liver":"717.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"Hepatocytes":"613.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"86","RNA cancer specific FPKM":{"liver cancer":"108.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"HDLM-2":"6.6","OE19":"2.9"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044720","HPA068265"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3800000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Nucleoli fibrillar center","Endoplasmic reticulum"],"Antibody RRID":{"HPA044720":"AB_2679058","HPA068265":"AB_2685966"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"2.5","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"41.8","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"717.5","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"1.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"1.1","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.6","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"6.6","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"1.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"2.9","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"37.1","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"7.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"13.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"613.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"14.5","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"2.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"AKT1","Gene synonym":["AKT","PKB","PRKBA","RAC","RAC-alpha"],"Ensembl":"ENSG00000142208","Gene description":"AKT serine\/threonine kinase 1","Uniprot":["P31749"],"Chromosome":"14","Position":"104769349-104795751","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins","Transporters"],"Biological process":["Apoptosis","Carbohydrate metabolism","Glucose metabolism","Glycogen biosynthesis","Glycogen metabolism","Neurogenesis","Sugar transport","Translation regulation","Transport"],"Molecular function":["Developmental protein","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"61.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"61.5"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"558.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002891","CAB003765"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 30: Mammary glandular cells - Lactation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Microtubules"],"Antibody RRID":{"CAB003765":"AB_562035","HPA002891":"AB_1078123"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.83e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.12e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Tissue RNA - adipose tissue [nTPM]":"71.5","Tissue RNA - adrenal gland [nTPM]":"102.7","Tissue RNA - amygdala [nTPM]":"45.9","Tissue RNA - appendix [nTPM]":"57.7","Tissue RNA - basal ganglia [nTPM]":"45.5","Tissue RNA - bone marrow [nTPM]":"51.2","Tissue RNA - breast [nTPM]":"61.2","Tissue RNA - cerebellum [nTPM]":"43.7","Tissue RNA - cerebral cortex [nTPM]":"53.2","Tissue RNA - cervix [nTPM]":"52.0","Tissue RNA - choroid plexus [nTPM]":"50.4","Tissue RNA - colon [nTPM]":"85.0","Tissue RNA - duodenum [nTPM]":"50.8","Tissue RNA - endometrium 1 [nTPM]":"59.5","Tissue RNA - epididymis [nTPM]":"23.2","Tissue RNA - esophagus [nTPM]":"70.7","Tissue RNA - fallopian tube [nTPM]":"53.7","Tissue RNA - gallbladder [nTPM]":"50.0","Tissue RNA - heart muscle [nTPM]":"105.9","Tissue RNA - hippocampal formation [nTPM]":"45.2","Tissue RNA - hypothalamus [nTPM]":"44.3","Tissue RNA - kidney [nTPM]":"54.3","Tissue RNA - liver [nTPM]":"97.3","Tissue RNA - lung [nTPM]":"69.2","Tissue RNA - lymph node [nTPM]":"51.9","Tissue RNA - medulla oblongata [nTPM]":"50.5","Tissue RNA - midbrain [nTPM]":"45.7","Tissue RNA - ovary [nTPM]":"43.7","Tissue RNA - pancreas [nTPM]":"94.3","Tissue RNA - parathyroid gland [nTPM]":"53.0","Tissue RNA - pituitary gland [nTPM]":"35.9","Tissue RNA - placenta [nTPM]":"55.4","Tissue RNA - pons [nTPM]":"45.0","Tissue RNA - prostate [nTPM]":"67.2","Tissue RNA - rectum [nTPM]":"39.6","Tissue RNA - retina [nTPM]":"25.1","Tissue RNA - salivary gland [nTPM]":"67.7","Tissue RNA - seminal vesicle [nTPM]":"73.0","Tissue RNA - skeletal muscle [nTPM]":"58.1","Tissue RNA - skin 1 [nTPM]":"45.0","Tissue RNA - small intestine [nTPM]":"53.3","Tissue RNA - smooth muscle [nTPM]":"63.4","Tissue RNA - spinal cord [nTPM]":"47.4","Tissue RNA - spleen [nTPM]":"63.7","Tissue RNA - stomach 1 [nTPM]":"77.8","Tissue RNA - testis [nTPM]":"23.9","Tissue RNA - thalamus [nTPM]":"48.0","Tissue RNA - thymus [nTPM]":"52.4","Tissue RNA - thyroid gland [nTPM]":"52.3","Tissue RNA - tongue [nTPM]":"64.9","Tissue RNA - tonsil [nTPM]":"40.3","Tissue RNA - urinary bladder [nTPM]":"72.6","Tissue RNA - vagina [nTPM]":"48.4","Tissue RNA - white matter [nTPM]":"43.3","Cell RNA - A-431 [nTPM]":"77.3","Cell RNA - A549 [nTPM]":"150.5","Cell RNA - AF22 [nTPM]":"124.6","Cell RNA - AN3-CA [nTPM]":"186.9","Cell RNA - ASC diff [nTPM]":"95.2","Cell RNA - ASC TERT1 [nTPM]":"97.7","Cell RNA - BEWO [nTPM]":"136.9","Cell RNA - BJ [nTPM]":"142.3","Cell RNA - BJ hTERT+ [nTPM]":"171.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"204.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"163.6","Cell RNA - CACO-2 [nTPM]":"96.8","Cell RNA - CAPAN-2 [nTPM]":"92.8","Cell RNA - Daudi [nTPM]":"91.2","Cell RNA - EFO-21 [nTPM]":"105.5","Cell RNA - fHDF\/TERT166 [nTPM]":"196.6","Cell RNA - GAMG [nTPM]":"102.8","Cell RNA - HaCaT [nTPM]":"99.4","Cell RNA - HAP1 [nTPM]":"89.5","Cell RNA - HBEC3-KT [nTPM]":"131.9","Cell RNA - HBF TERT88 [nTPM]":"90.1","Cell RNA - HDLM-2 [nTPM]":"214.3","Cell RNA - HEK 293 [nTPM]":"36.2","Cell RNA - HEL [nTPM]":"70.6","Cell RNA - HeLa [nTPM]":"90.4","Cell RNA - Hep G2 [nTPM]":"103.2","Cell RNA - HHSteC [nTPM]":"104.6","Cell RNA - HL-60 [nTPM]":"117.5","Cell RNA - HMC-1 [nTPM]":"178.0","Cell RNA - HSkMC [nTPM]":"140.0","Cell RNA - hTCEpi [nTPM]":"109.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"102.9","Cell RNA - hTERT-HME1 [nTPM]":"68.1","Cell RNA - hTERT-RPE1 [nTPM]":"98.2","Cell RNA - HUVEC TERT2 [nTPM]":"154.4","Cell RNA - JURKAT [nTPM]":"87.5","Cell RNA - K-562 [nTPM]":"62.1","Cell RNA - Karpas-707 [nTPM]":"102.2","Cell RNA - LHCN-M2 [nTPM]":"134.1","Cell RNA - MCF7 [nTPM]":"558.3","Cell RNA - MOLT-4 [nTPM]":"145.3","Cell RNA - NB-4 [nTPM]":"146.8","Cell RNA - NTERA-2 [nTPM]":"32.6","Cell RNA - OE19 [nTPM]":"153.5","Cell RNA - PC-3 [nTPM]":"107.2","Cell RNA - REH [nTPM]":"137.5","Cell RNA - RH-30 [nTPM]":"111.9","Cell RNA - RPMI-8226 [nTPM]":"60.5","Cell RNA - RPTEC TERT1 [nTPM]":"94.8","Cell RNA - RT4 [nTPM]":"189.5","Cell RNA - SCLC-21H [nTPM]":"141.2","Cell RNA - SH-SY5Y [nTPM]":"117.2","Cell RNA - SiHa [nTPM]":"117.3","Cell RNA - SK-BR-3 [nTPM]":"152.2","Cell RNA - SK-MEL-30 [nTPM]":"88.9","Cell RNA - SuSa [nTPM]":"56.8","Cell RNA - T-47d [nTPM]":"195.7","Cell RNA - THP-1 [nTPM]":"170.2","Cell RNA - TIME [nTPM]":"123.5","Cell RNA - U-138 MG [nTPM]":"133.2","Cell RNA - U-2 OS [nTPM]":"63.2","Cell RNA - U-2197 [nTPM]":"192.3","Cell RNA - U-251 MG [nTPM]":"145.1","Cell RNA - U-266\/70 [nTPM]":"105.4","Cell RNA - U-266\/84 [nTPM]":"52.6","Cell RNA - U-698 [nTPM]":"80.7","Cell RNA - U-87 MG [nTPM]":"113.7","Cell RNA - U-937 [nTPM]":"96.7","Cell RNA - WM-115 [nTPM]":"162.0","Blood RNA - basophil [nTPM]":"6.4","Blood RNA - classical monocyte [nTPM]":"9.9","Blood RNA - eosinophil [nTPM]":"61.5","Blood RNA - gdT-cell [nTPM]":"10.0","Blood RNA - intermediate monocyte [nTPM]":"10.3","Blood RNA - MAIT T-cell [nTPM]":"7.2","Blood RNA - memory B-cell [nTPM]":"5.5","Blood RNA - memory CD4 T-cell [nTPM]":"8.7","Blood RNA - memory CD8 T-cell [nTPM]":"11.4","Blood RNA - myeloid DC [nTPM]":"7.0","Blood RNA - naive B-cell [nTPM]":"7.2","Blood RNA - naive CD4 T-cell [nTPM]":"4.6","Blood RNA - naive CD8 T-cell [nTPM]":"10.1","Blood RNA - neutrophil [nTPM]":"22.6","Blood RNA - NK-cell [nTPM]":"11.0","Blood RNA - non-classical monocyte [nTPM]":"12.4","Blood RNA - plasmacytoid DC [nTPM]":"10.0","Blood RNA - T-reg [nTPM]":"9.0","Blood RNA - total PBMC [nTPM]":"6.3","Brain RNA - amygdala [nTPM]":"45.9","Brain RNA - basal ganglia [nTPM]":"45.5","Brain RNA - cerebellum [nTPM]":"43.7","Brain RNA - cerebral cortex [nTPM]":"53.2","Brain RNA - hippocampal formation [nTPM]":"45.2","Brain RNA - hypothalamus [nTPM]":"44.3","Brain RNA - medulla oblongata [nTPM]":"50.5","Brain RNA - midbrain [nTPM]":"45.7","Brain RNA - pons [nTPM]":"45.0","Brain RNA - spinal cord [nTPM]":"47.4","Brain RNA - thalamus [nTPM]":"48.0","Brain RNA - white matter [nTPM]":"43.3","Single Cell Type RNA - Adipocytes [nTPM]":"45.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.4","Single Cell Type RNA - Astrocytes [nTPM]":"16.6","Single Cell Type RNA - B-cells [nTPM]":"13.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Bipolar cells [nTPM]":"26.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"58.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"39.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"17.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.4","Single Cell Type RNA - dendritic cells [nTPM]":"54.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"40.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"23.6","Single Cell Type RNA - Early spermatids [nTPM]":"1.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"28.1","Single Cell Type RNA - Endothelial cells [nTPM]":"27.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"30.0","Single Cell Type RNA - Erythroid cells [nTPM]":"11.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"35.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"31.8","Single Cell Type RNA - Fibroblasts [nTPM]":"24.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"26.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.8","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"40.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.2","Single Cell Type RNA - Hepatocytes [nTPM]":"42.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.2","Single Cell Type RNA - Horizontal cells [nTPM]":"42.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"37.3","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"23.3","Single Cell Type RNA - Langerhans cells [nTPM]":"21.4","Single Cell Type RNA - Late spermatids [nTPM]":"3.3","Single Cell Type RNA - Leydig cells [nTPM]":"28.6","Single Cell Type RNA - Macrophages [nTPM]":"28.0","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"23.1","Single Cell Type RNA - Muller glia cells [nTPM]":"51.2","Single Cell Type RNA - NK-cells [nTPM]":"24.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"53.3","Single Cell Type RNA - Paneth cells [nTPM]":"22.1","Single Cell Type RNA - Peritubular cells [nTPM]":"30.9","Single Cell Type RNA - Plasma cells [nTPM]":"10.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"38.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"26.6","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"24.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"29.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.8","Single Cell Type RNA - Spermatogonia [nTPM]":"5.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.4","Single Cell Type RNA - T-cells [nTPM]":"23.3","Single Cell Type RNA - Theca cells [nTPM]":"34.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"33.7","Single Cell Type RNA - Urothelial cells [nTPM]":"33.4"},{"Gene":"AKT2","Gene synonym":["PKB\u00c3\u017d\u00c2\u00b2"],"Ensembl":"ENSG00000105221","Gene description":"AKT serine\/threonine kinase 2","Uniprot":["P31751"],"Chromosome":"19","Position":"40230317-40285536","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["Apoptosis","Carbohydrate metabolism","Glucose metabolism","Glycogen biosynthesis","Glycogen metabolism","Sugar transport","Translation regulation","Transport"],"Molecular function":["Developmental protein","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Diabetes mellitus","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004204","HPA064521"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB004204":"AB_626659","HPA064521":"AB_2685278"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.05e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.74e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Tissue RNA - adipose tissue [nTPM]":"62.8","Tissue RNA - adrenal gland [nTPM]":"40.0","Tissue RNA - amygdala [nTPM]":"31.7","Tissue RNA - appendix [nTPM]":"37.3","Tissue RNA - basal ganglia [nTPM]":"31.3","Tissue RNA - bone marrow [nTPM]":"48.4","Tissue RNA - breast [nTPM]":"38.6","Tissue RNA - cerebellum [nTPM]":"58.3","Tissue RNA - cerebral cortex [nTPM]":"40.0","Tissue RNA - cervix [nTPM]":"49.8","Tissue RNA - choroid plexus [nTPM]":"55.1","Tissue RNA - colon [nTPM]":"42.3","Tissue RNA - duodenum [nTPM]":"24.5","Tissue RNA - endometrium 1 [nTPM]":"43.5","Tissue RNA - epididymis [nTPM]":"49.4","Tissue RNA - esophagus [nTPM]":"42.5","Tissue RNA - fallopian tube [nTPM]":"46.1","Tissue RNA - gallbladder [nTPM]":"25.1","Tissue RNA - heart muscle [nTPM]":"40.8","Tissue RNA - hippocampal formation [nTPM]":"31.5","Tissue RNA - hypothalamus [nTPM]":"24.5","Tissue RNA - kidney [nTPM]":"52.2","Tissue RNA - liver [nTPM]":"59.2","Tissue RNA - lung [nTPM]":"30.7","Tissue RNA - lymph node [nTPM]":"38.1","Tissue RNA - medulla oblongata [nTPM]":"32.0","Tissue RNA - midbrain [nTPM]":"26.0","Tissue RNA - ovary [nTPM]":"53.9","Tissue RNA - pancreas [nTPM]":"41.9","Tissue RNA - parathyroid gland [nTPM]":"58.5","Tissue RNA - pituitary gland [nTPM]":"47.8","Tissue RNA - placenta [nTPM]":"27.6","Tissue RNA - pons [nTPM]":"26.3","Tissue RNA - prostate [nTPM]":"41.2","Tissue RNA - rectum [nTPM]":"23.3","Tissue RNA - retina [nTPM]":"41.2","Tissue RNA - salivary gland [nTPM]":"32.5","Tissue RNA - seminal vesicle [nTPM]":"45.0","Tissue RNA - skeletal muscle [nTPM]":"101.3","Tissue RNA - skin 1 [nTPM]":"39.4","Tissue RNA - small intestine [nTPM]":"35.6","Tissue RNA - smooth muscle [nTPM]":"34.2","Tissue RNA - spinal cord [nTPM]":"22.1","Tissue RNA - spleen [nTPM]":"38.1","Tissue RNA - stomach 1 [nTPM]":"33.1","Tissue RNA - testis [nTPM]":"29.7","Tissue RNA - thalamus [nTPM]":"28.0","Tissue RNA - thymus [nTPM]":"53.4","Tissue RNA - thyroid gland [nTPM]":"100.1","Tissue RNA - tongue [nTPM]":"118.7","Tissue RNA - tonsil [nTPM]":"37.0","Tissue RNA - urinary bladder [nTPM]":"39.8","Tissue RNA - vagina [nTPM]":"41.5","Tissue RNA - white matter [nTPM]":"35.2","Cell RNA - A-431 [nTPM]":"66.2","Cell RNA - A549 [nTPM]":"160.1","Cell RNA - AF22 [nTPM]":"63.1","Cell RNA - AN3-CA [nTPM]":"61.5","Cell RNA - ASC diff [nTPM]":"72.0","Cell RNA - ASC TERT1 [nTPM]":"88.9","Cell RNA - BEWO [nTPM]":"32.5","Cell RNA - BJ [nTPM]":"41.7","Cell RNA - BJ hTERT+ [nTPM]":"63.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"87.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"77.9","Cell RNA - CACO-2 [nTPM]":"71.8","Cell RNA - CAPAN-2 [nTPM]":"60.8","Cell RNA - Daudi [nTPM]":"67.4","Cell RNA - EFO-21 [nTPM]":"36.8","Cell RNA - fHDF\/TERT166 [nTPM]":"96.3","Cell RNA - GAMG [nTPM]":"37.2","Cell RNA - HaCaT [nTPM]":"28.2","Cell RNA - HAP1 [nTPM]":"66.8","Cell RNA - HBEC3-KT [nTPM]":"90.0","Cell RNA - HBF TERT88 [nTPM]":"56.1","Cell RNA - HDLM-2 [nTPM]":"62.5","Cell RNA - HEK 293 [nTPM]":"74.3","Cell RNA - HEL [nTPM]":"43.4","Cell RNA - HeLa [nTPM]":"116.5","Cell RNA - Hep G2 [nTPM]":"44.7","Cell RNA - HHSteC [nTPM]":"45.8","Cell RNA - HL-60 [nTPM]":"50.7","Cell RNA - HMC-1 [nTPM]":"50.5","Cell RNA - HSkMC [nTPM]":"82.7","Cell RNA - hTCEpi [nTPM]":"53.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"58.6","Cell RNA - hTERT-HME1 [nTPM]":"56.4","Cell RNA - hTERT-RPE1 [nTPM]":"71.9","Cell RNA - HUVEC TERT2 [nTPM]":"19.0","Cell RNA - JURKAT [nTPM]":"73.0","Cell RNA - K-562 [nTPM]":"57.3","Cell RNA - Karpas-707 [nTPM]":"67.5","Cell RNA - LHCN-M2 [nTPM]":"49.8","Cell RNA - MCF7 [nTPM]":"54.6","Cell RNA - MOLT-4 [nTPM]":"81.1","Cell RNA - NB-4 [nTPM]":"24.7","Cell RNA - NTERA-2 [nTPM]":"31.7","Cell RNA - OE19 [nTPM]":"73.7","Cell RNA - PC-3 [nTPM]":"41.5","Cell RNA - REH [nTPM]":"54.2","Cell RNA - RH-30 [nTPM]":"32.1","Cell RNA - RPMI-8226 [nTPM]":"48.5","Cell RNA - RPTEC TERT1 [nTPM]":"68.3","Cell RNA - RT4 [nTPM]":"105.7","Cell RNA - SCLC-21H [nTPM]":"82.7","Cell RNA - SH-SY5Y [nTPM]":"49.8","Cell RNA - SiHa [nTPM]":"43.3","Cell RNA - SK-BR-3 [nTPM]":"75.0","Cell RNA - SK-MEL-30 [nTPM]":"35.0","Cell RNA - SuSa [nTPM]":"62.5","Cell RNA - T-47d [nTPM]":"59.8","Cell RNA - THP-1 [nTPM]":"64.9","Cell RNA - TIME [nTPM]":"18.8","Cell RNA - U-138 MG [nTPM]":"52.7","Cell RNA - U-2 OS [nTPM]":"51.5","Cell RNA - U-2197 [nTPM]":"47.3","Cell RNA - U-251 MG [nTPM]":"67.6","Cell RNA - U-266\/70 [nTPM]":"61.5","Cell RNA - U-266\/84 [nTPM]":"59.0","Cell RNA - U-698 [nTPM]":"56.4","Cell RNA - U-87 MG [nTPM]":"52.6","Cell RNA - U-937 [nTPM]":"59.7","Cell RNA - WM-115 [nTPM]":"44.3","Blood RNA - basophil [nTPM]":"5.7","Blood RNA - classical monocyte [nTPM]":"2.6","Blood RNA - eosinophil [nTPM]":"2.1","Blood RNA - gdT-cell [nTPM]":"2.2","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"2.2","Blood RNA - memory B-cell [nTPM]":"1.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.8","Blood RNA - memory CD8 T-cell [nTPM]":"1.5","Blood RNA - myeloid DC [nTPM]":"1.7","Blood RNA - naive B-cell [nTPM]":"2.9","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"2.6","Blood RNA - neutrophil [nTPM]":"4.0","Blood RNA - NK-cell [nTPM]":"1.7","Blood RNA - non-classical monocyte [nTPM]":"1.6","Blood RNA - plasmacytoid DC [nTPM]":"4.9","Blood RNA - T-reg [nTPM]":"1.6","Blood RNA - total PBMC [nTPM]":"1.7","Brain RNA - amygdala [nTPM]":"31.7","Brain RNA - basal ganglia [nTPM]":"31.3","Brain RNA - cerebellum [nTPM]":"58.3","Brain RNA - cerebral cortex [nTPM]":"40.0","Brain RNA - hippocampal formation [nTPM]":"31.5","Brain RNA - hypothalamus [nTPM]":"24.5","Brain RNA - medulla oblongata [nTPM]":"32.0","Brain RNA - midbrain [nTPM]":"26.0","Brain RNA - pons [nTPM]":"26.3","Brain RNA - spinal cord [nTPM]":"22.1","Brain RNA - thalamus [nTPM]":"28.0","Brain RNA - white matter [nTPM]":"35.2","Single Cell Type RNA - Adipocytes [nTPM]":"18.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.9","Single Cell Type RNA - Astrocytes [nTPM]":"51.2","Single Cell Type RNA - B-cells [nTPM]":"33.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"23.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"20.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.2","Single Cell Type RNA - Bipolar cells [nTPM]":"67.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"31.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"18.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"60.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"31.3","Single Cell Type RNA - dendritic cells [nTPM]":"26.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"19.7","Single Cell Type RNA - Early spermatids [nTPM]":"5.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"26.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.7","Single Cell Type RNA - Endothelial cells [nTPM]":"17.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.2","Single Cell Type RNA - Erythroid cells [nTPM]":"19.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"30.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"25.2","Single Cell Type RNA - Fibroblasts [nTPM]":"27.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.8","Single Cell Type RNA - granulocytes [nTPM]":"14.0","Single Cell Type RNA - Granulosa cells [nTPM]":"44.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.9","Single Cell Type RNA - Hepatocytes [nTPM]":"87.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.3","Single Cell Type RNA - Horizontal cells [nTPM]":"60.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.1","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"23.2","Single Cell Type RNA - Langerhans cells [nTPM]":"17.5","Single Cell Type RNA - Late spermatids [nTPM]":"10.5","Single Cell Type RNA - Leydig cells [nTPM]":"42.9","Single Cell Type RNA - Macrophages [nTPM]":"20.0","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"21.7","Single Cell Type RNA - Muller glia cells [nTPM]":"46.2","Single Cell Type RNA - NK-cells [nTPM]":"50.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"41.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"40.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"24.8","Single Cell Type RNA - Paneth cells [nTPM]":"16.9","Single Cell Type RNA - Peritubular cells [nTPM]":"26.7","Single Cell Type RNA - Plasma cells [nTPM]":"30.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"29.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"21.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"24.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"24.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"97.4","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"29.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"25.0","Single Cell Type RNA - Spermatocytes [nTPM]":"14.8","Single Cell Type RNA - Spermatogonia [nTPM]":"15.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"31.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"38.7","Single Cell Type RNA - T-cells [nTPM]":"23.1","Single Cell Type RNA - Theca cells [nTPM]":"56.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.3","Single Cell Type RNA - Urothelial cells [nTPM]":"29.4"},{"Gene":"AKT3","Gene synonym":["PKBG","PRKBG","RAC-gamma"],"Ensembl":"ENSG00000117020","Gene description":"AKT serine\/threonine kinase 3","Uniprot":["Q9Y243"],"Chromosome":"1","Position":"243488233-243851079","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"59.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Astrocytes":"457.4","Excitatory neurons":"756.1","Inhibitory neurons":"514.5","Microglial cells":"414.1","Oligodendrocyte precursor cells":"633.3","Oligodendrocytes":"475.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013090","HPA026441"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB013090":"AB_2533692","HPA026441":"AB_1844711"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.27e-4"},"Tissue RNA - adipose tissue [nTPM]":"19.3","Tissue RNA - adrenal gland [nTPM]":"9.7","Tissue RNA - amygdala [nTPM]":"13.4","Tissue RNA - appendix [nTPM]":"6.0","Tissue RNA - basal ganglia [nTPM]":"17.0","Tissue RNA - bone marrow [nTPM]":"3.8","Tissue RNA - breast [nTPM]":"15.5","Tissue RNA - cerebellum [nTPM]":"59.9","Tissue RNA - cerebral cortex [nTPM]":"36.6","Tissue RNA - cervix [nTPM]":"20.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"24.5","Tissue RNA - duodenum [nTPM]":"2.6","Tissue RNA - endometrium 1 [nTPM]":"22.7","Tissue RNA - epididymis [nTPM]":"8.6","Tissue RNA - esophagus [nTPM]":"5.9","Tissue RNA - fallopian tube [nTPM]":"20.3","Tissue RNA - gallbladder [nTPM]":"8.2","Tissue RNA - heart muscle [nTPM]":"11.8","Tissue RNA - hippocampal formation [nTPM]":"22.8","Tissue RNA - hypothalamus [nTPM]":"5.6","Tissue RNA - kidney [nTPM]":"11.2","Tissue RNA - liver [nTPM]":"4.7","Tissue RNA - lung [nTPM]":"15.3","Tissue RNA - lymph node [nTPM]":"5.9","Tissue RNA - medulla oblongata [nTPM]":"1.2","Tissue RNA - midbrain [nTPM]":"3.9","Tissue RNA - ovary [nTPM]":"26.4","Tissue RNA - pancreas [nTPM]":"4.5","Tissue RNA - parathyroid gland [nTPM]":"7.4","Tissue RNA - pituitary gland [nTPM]":"13.9","Tissue RNA - placenta [nTPM]":"13.1","Tissue RNA - pons [nTPM]":"7.4","Tissue RNA - prostate [nTPM]":"15.8","Tissue RNA - rectum [nTPM]":"4.9","Tissue RNA - retina [nTPM]":"17.0","Tissue RNA - salivary gland [nTPM]":"5.1","Tissue RNA - seminal vesicle [nTPM]":"15.6","Tissue RNA - skeletal muscle [nTPM]":"5.9","Tissue RNA - skin 1 [nTPM]":"6.3","Tissue RNA - small intestine [nTPM]":"11.8","Tissue RNA - smooth muscle [nTPM]":"15.7","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"8.1","Tissue RNA - stomach 1 [nTPM]":"10.2","Tissue RNA - testis [nTPM]":"9.7","Tissue RNA - thalamus [nTPM]":"20.3","Tissue RNA - thymus [nTPM]":"7.0","Tissue RNA - thyroid gland [nTPM]":"14.4","Tissue RNA - tongue [nTPM]":"11.5","Tissue RNA - tonsil [nTPM]":"4.6","Tissue RNA - urinary bladder [nTPM]":"18.8","Tissue RNA - vagina [nTPM]":"14.8","Tissue RNA - white matter [nTPM]":"31.1","Cell RNA - A-431 [nTPM]":"30.8","Cell RNA - A549 [nTPM]":"7.2","Cell RNA - AF22 [nTPM]":"31.0","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"16.9","Cell RNA - ASC TERT1 [nTPM]":"20.6","Cell RNA - BEWO [nTPM]":"13.9","Cell RNA - BJ [nTPM]":"20.8","Cell RNA - BJ hTERT+ [nTPM]":"22.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.9","Cell RNA - CACO-2 [nTPM]":"1.1","Cell RNA - CAPAN-2 [nTPM]":"13.9","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"3.0","Cell RNA - fHDF\/TERT166 [nTPM]":"28.9","Cell RNA - GAMG [nTPM]":"12.1","Cell RNA - HaCaT [nTPM]":"1.2","Cell RNA - HAP1 [nTPM]":"16.3","Cell RNA - HBEC3-KT [nTPM]":"8.5","Cell RNA - HBF TERT88 [nTPM]":"18.9","Cell RNA - HDLM-2 [nTPM]":"9.0","Cell RNA - HEK 293 [nTPM]":"15.3","Cell RNA - HEL [nTPM]":"1.0","Cell RNA - HeLa [nTPM]":"1.0","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"11.7","Cell RNA - HL-60 [nTPM]":"0.6","Cell RNA - HMC-1 [nTPM]":"6.5","Cell RNA - HSkMC [nTPM]":"11.3","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.5","Cell RNA - hTERT-HME1 [nTPM]":"16.9","Cell RNA - hTERT-RPE1 [nTPM]":"30.3","Cell RNA - HUVEC TERT2 [nTPM]":"30.2","Cell RNA - JURKAT [nTPM]":"7.2","Cell RNA - K-562 [nTPM]":"0.5","Cell RNA - Karpas-707 [nTPM]":"1.1","Cell RNA - LHCN-M2 [nTPM]":"9.0","Cell RNA - MCF7 [nTPM]":"0.9","Cell RNA - MOLT-4 [nTPM]":"7.6","Cell RNA - NB-4 [nTPM]":"3.3","Cell RNA - NTERA-2 [nTPM]":"14.4","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"5.1","Cell RNA - REH [nTPM]":"4.2","Cell RNA - RH-30 [nTPM]":"19.7","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"4.8","Cell RNA - RT4 [nTPM]":"4.1","Cell RNA - SCLC-21H [nTPM]":"31.4","Cell RNA - SH-SY5Y [nTPM]":"41.9","Cell RNA - SiHa [nTPM]":"1.3","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"40.1","Cell RNA - SuSa [nTPM]":"19.1","Cell RNA - T-47d [nTPM]":"1.9","Cell RNA - THP-1 [nTPM]":"21.5","Cell RNA - TIME [nTPM]":"25.6","Cell RNA - U-138 MG [nTPM]":"22.7","Cell RNA - U-2 OS [nTPM]":"17.7","Cell RNA - U-2197 [nTPM]":"1.1","Cell RNA - U-251 MG [nTPM]":"19.5","Cell RNA - U-266\/70 [nTPM]":"4.6","Cell RNA - U-266\/84 [nTPM]":"4.6","Cell RNA - U-698 [nTPM]":"7.1","Cell RNA - U-87 MG [nTPM]":"19.4","Cell RNA - U-937 [nTPM]":"5.2","Cell RNA - WM-115 [nTPM]":"25.3","Blood RNA - basophil [nTPM]":"1.3","Blood RNA - classical monocyte [nTPM]":"0.8","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"1.1","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.8","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"1.4","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"13.4","Brain RNA - basal ganglia [nTPM]":"17.0","Brain RNA - cerebellum [nTPM]":"59.9","Brain RNA - cerebral cortex [nTPM]":"36.6","Brain RNA - hippocampal formation [nTPM]":"22.8","Brain RNA - hypothalamus [nTPM]":"5.6","Brain RNA - medulla oblongata [nTPM]":"1.2","Brain RNA - midbrain [nTPM]":"3.9","Brain RNA - pons [nTPM]":"7.4","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"20.3","Brain RNA - white matter [nTPM]":"31.1","Single Cell Type RNA - Adipocytes [nTPM]":"65.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.2","Single Cell Type RNA - Astrocytes [nTPM]":"457.4","Single Cell Type RNA - B-cells [nTPM]":"22.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Bipolar cells [nTPM]":"43.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"2.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.0","Single Cell Type RNA - dendritic cells [nTPM]":"24.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"11.6","Single Cell Type RNA - Early spermatids [nTPM]":"82.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"35.5","Single Cell Type RNA - Endothelial cells [nTPM]":"43.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"756.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.0","Single Cell Type RNA - Fibroblasts [nTPM]":"27.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.1","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"29.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"48.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.9","Single Cell Type RNA - Horizontal cells [nTPM]":"42.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"514.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"10.5","Single Cell Type RNA - Langerhans cells [nTPM]":"12.5","Single Cell Type RNA - Late spermatids [nTPM]":"72.8","Single Cell Type RNA - Leydig cells [nTPM]":"27.4","Single Cell Type RNA - Macrophages [nTPM]":"9.5","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"414.1","Single Cell Type RNA - monocytes [nTPM]":"8.6","Single Cell Type RNA - Muller glia cells [nTPM]":"20.1","Single Cell Type RNA - NK-cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"633.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"475.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"35.3","Single Cell Type RNA - Plasma cells [nTPM]":"14.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"27.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"35.0","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"40.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"35.6","Single Cell Type RNA - Spermatocytes [nTPM]":"15.0","Single Cell Type RNA - Spermatogonia [nTPM]":"14.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.4","Single Cell Type RNA - T-cells [nTPM]":"27.8","Single Cell Type RNA - Theca cells [nTPM]":"8.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"12.2"},{"Gene":"ALAS2","Gene synonym":["ASB"],"Ensembl":"ENSG00000158578","Gene description":"5'-aminolevulinate synthase 2","Uniprot":["P22557"],"Chromosome":"X","Position":"55009055-55030977","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Heme biosynthesis"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"bone marrow":"606.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"166","RNA single cell type specific nTPM":{"Erythroid cells":"2366.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"0.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"plasmacytoid DC":"1.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"1.6"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"93","RNA cell line specific nTPM":{"HEL":"71.7","K-562":"85.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.9","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"0.9","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"0.9","Tissue RNA - bone marrow [nTPM]":"606.2","Tissue RNA - breast [nTPM]":"0.6","Tissue RNA - cerebellum [nTPM]":"0.8","Tissue RNA - cerebral cortex [nTPM]":"2.5","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"1.6","Tissue RNA - colon [nTPM]":"0.5","Tissue RNA - duodenum [nTPM]":"0.6","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.8","Tissue RNA - fallopian tube [nTPM]":"1.1","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"3.4","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"0.8","Tissue RNA - kidney [nTPM]":"2.5","Tissue RNA - liver [nTPM]":"3.2","Tissue RNA - lung [nTPM]":"5.2","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"1.8","Tissue RNA - midbrain [nTPM]":"1.2","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.2","Tissue RNA - placenta [nTPM]":"44.9","Tissue RNA - pons [nTPM]":"1.6","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"1.0","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"1.6","Tissue RNA - spleen [nTPM]":"25.2","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"1.2","Tissue RNA - tongue [nTPM]":"18.2","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.6","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"1.3","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.8","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.6","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"71.7","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"85.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.6","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"1.6","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"5.9","Brain RNA - amygdala [nTPM]":"0.9","Brain RNA - basal ganglia [nTPM]":"0.9","Brain RNA - cerebellum [nTPM]":"0.8","Brain RNA - cerebral cortex [nTPM]":"2.5","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"0.8","Brain RNA - medulla oblongata [nTPM]":"1.8","Brain RNA - midbrain [nTPM]":"1.2","Brain RNA - pons [nTPM]":"1.6","Brain RNA - spinal cord [nTPM]":"1.6","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"1.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"4.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"2366.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.8","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"1.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"5.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"7.3","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"ALDH18A1","Gene synonym":["GSAS","P5CS","PYCS","SPG9"],"Ensembl":"ENSG00000059573","Gene description":"Aldehyde dehydrogenase 18 family member A1","Uniprot":["P54886"],"Chromosome":"10","Position":"95605941-95656711","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Amino-acid biosynthesis","Proline biosynthesis"],"Molecular function":["Kinase","Multifunctional enzyme","Oxidoreductase","Transferase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Mental retardation","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"120.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"80.5","Granulosa cells":"81.6","Proximal enterocytes":"79.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008333","HPA012604"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"48000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA008333":"AB_1078125","HPA012604":"AB_1844721"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.20e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.60e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.3","Tissue RNA - adrenal gland [nTPM]":"16.1","Tissue RNA - amygdala [nTPM]":"12.2","Tissue RNA - appendix [nTPM]":"21.2","Tissue RNA - basal ganglia [nTPM]":"12.6","Tissue RNA - bone marrow [nTPM]":"16.7","Tissue RNA - breast [nTPM]":"20.2","Tissue RNA - cerebellum [nTPM]":"12.4","Tissue RNA - cerebral cortex [nTPM]":"13.1","Tissue RNA - cervix [nTPM]":"33.4","Tissue RNA - choroid plexus [nTPM]":"21.0","Tissue RNA - colon [nTPM]":"51.9","Tissue RNA - duodenum [nTPM]":"89.3","Tissue RNA - endometrium 1 [nTPM]":"18.5","Tissue RNA - epididymis [nTPM]":"30.9","Tissue RNA - esophagus [nTPM]":"21.0","Tissue RNA - fallopian tube [nTPM]":"21.9","Tissue RNA - gallbladder [nTPM]":"25.2","Tissue RNA - heart muscle [nTPM]":"11.5","Tissue RNA - hippocampal formation [nTPM]":"12.2","Tissue RNA - hypothalamus [nTPM]":"13.6","Tissue RNA - kidney [nTPM]":"17.7","Tissue RNA - liver [nTPM]":"24.3","Tissue RNA - lung [nTPM]":"10.8","Tissue RNA - lymph node [nTPM]":"22.0","Tissue RNA - medulla oblongata [nTPM]":"12.4","Tissue RNA - midbrain [nTPM]":"14.7","Tissue RNA - ovary [nTPM]":"16.7","Tissue RNA - pancreas [nTPM]":"61.8","Tissue RNA - parathyroid gland [nTPM]":"33.5","Tissue RNA - pituitary gland [nTPM]":"28.2","Tissue RNA - placenta [nTPM]":"26.3","Tissue RNA - pons [nTPM]":"13.1","Tissue RNA - prostate [nTPM]":"24.2","Tissue RNA - rectum [nTPM]":"49.3","Tissue RNA - retina [nTPM]":"11.4","Tissue RNA - salivary gland [nTPM]":"120.1","Tissue RNA - seminal vesicle [nTPM]":"24.9","Tissue RNA - skeletal muscle [nTPM]":"4.3","Tissue RNA - skin 1 [nTPM]":"22.4","Tissue RNA - small intestine [nTPM]":"73.1","Tissue RNA - smooth muscle [nTPM]":"26.3","Tissue RNA - spinal cord [nTPM]":"12.7","Tissue RNA - spleen [nTPM]":"12.1","Tissue RNA - stomach 1 [nTPM]":"40.5","Tissue RNA - testis [nTPM]":"11.7","Tissue RNA - thalamus [nTPM]":"14.0","Tissue RNA - thymus [nTPM]":"17.2","Tissue RNA - thyroid gland [nTPM]":"37.5","Tissue RNA - tongue [nTPM]":"5.5","Tissue RNA - tonsil [nTPM]":"26.9","Tissue RNA - urinary bladder [nTPM]":"25.2","Tissue RNA - vagina [nTPM]":"14.3","Tissue RNA - white matter [nTPM]":"13.1","Cell RNA - A-431 [nTPM]":"66.5","Cell RNA - A549 [nTPM]":"61.6","Cell RNA - AF22 [nTPM]":"57.9","Cell RNA - AN3-CA [nTPM]":"152.7","Cell RNA - ASC diff [nTPM]":"76.0","Cell RNA - ASC TERT1 [nTPM]":"72.9","Cell RNA - BEWO [nTPM]":"62.2","Cell RNA - BJ [nTPM]":"75.6","Cell RNA - BJ hTERT+ [nTPM]":"112.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"75.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"93.7","Cell RNA - CACO-2 [nTPM]":"124.4","Cell RNA - CAPAN-2 [nTPM]":"51.6","Cell RNA - Daudi [nTPM]":"223.7","Cell RNA - EFO-21 [nTPM]":"68.9","Cell RNA - fHDF\/TERT166 [nTPM]":"119.7","Cell RNA - GAMG [nTPM]":"36.2","Cell RNA - HaCaT [nTPM]":"85.6","Cell RNA - HAP1 [nTPM]":"117.1","Cell RNA - HBEC3-KT [nTPM]":"77.8","Cell RNA - HBF TERT88 [nTPM]":"84.6","Cell RNA - HDLM-2 [nTPM]":"64.0","Cell RNA - HEK 293 [nTPM]":"92.0","Cell RNA - HEL [nTPM]":"71.2","Cell RNA - HeLa [nTPM]":"40.5","Cell RNA - Hep G2 [nTPM]":"177.9","Cell RNA - HHSteC [nTPM]":"49.7","Cell RNA - HL-60 [nTPM]":"125.6","Cell RNA - HMC-1 [nTPM]":"76.1","Cell RNA - HSkMC [nTPM]":"77.0","Cell RNA - hTCEpi [nTPM]":"46.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"61.5","Cell RNA - hTERT-HME1 [nTPM]":"119.1","Cell RNA - hTERT-RPE1 [nTPM]":"124.5","Cell RNA - HUVEC TERT2 [nTPM]":"79.9","Cell RNA - JURKAT [nTPM]":"82.6","Cell RNA - K-562 [nTPM]":"67.5","Cell RNA - Karpas-707 [nTPM]":"46.0","Cell RNA - LHCN-M2 [nTPM]":"57.1","Cell RNA - MCF7 [nTPM]":"95.0","Cell RNA - MOLT-4 [nTPM]":"114.5","Cell RNA - NB-4 [nTPM]":"80.5","Cell RNA - NTERA-2 [nTPM]":"68.6","Cell RNA - OE19 [nTPM]":"109.2","Cell RNA - PC-3 [nTPM]":"60.7","Cell RNA - REH [nTPM]":"105.9","Cell RNA - RH-30 [nTPM]":"66.3","Cell RNA - RPMI-8226 [nTPM]":"76.9","Cell RNA - RPTEC TERT1 [nTPM]":"88.3","Cell RNA - RT4 [nTPM]":"49.7","Cell RNA - SCLC-21H [nTPM]":"57.5","Cell RNA - SH-SY5Y [nTPM]":"56.9","Cell RNA - SiHa [nTPM]":"60.1","Cell RNA - SK-BR-3 [nTPM]":"47.1","Cell RNA - SK-MEL-30 [nTPM]":"56.9","Cell RNA - SuSa [nTPM]":"66.0","Cell RNA - T-47d [nTPM]":"70.5","Cell RNA - THP-1 [nTPM]":"57.9","Cell RNA - TIME [nTPM]":"66.7","Cell RNA - U-138 MG [nTPM]":"31.1","Cell RNA - U-2 OS [nTPM]":"49.0","Cell RNA - U-2197 [nTPM]":"80.9","Cell RNA - U-251 MG [nTPM]":"88.2","Cell RNA - U-266\/70 [nTPM]":"52.4","Cell RNA - U-266\/84 [nTPM]":"41.7","Cell RNA - U-698 [nTPM]":"135.8","Cell RNA - U-87 MG [nTPM]":"60.4","Cell RNA - U-937 [nTPM]":"142.8","Cell RNA - WM-115 [nTPM]":"40.7","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"2.6","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"27.3","Blood RNA - intermediate monocyte [nTPM]":"5.2","Blood RNA - MAIT T-cell [nTPM]":"28.7","Blood RNA - memory B-cell [nTPM]":"23.0","Blood RNA - memory CD4 T-cell [nTPM]":"24.5","Blood RNA - memory CD8 T-cell [nTPM]":"28.3","Blood RNA - myeloid DC [nTPM]":"9.6","Blood RNA - naive B-cell [nTPM]":"16.1","Blood RNA - naive CD4 T-cell [nTPM]":"20.7","Blood RNA - naive CD8 T-cell [nTPM]":"23.1","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"26.3","Blood RNA - non-classical monocyte [nTPM]":"8.3","Blood RNA - plasmacytoid DC [nTPM]":"5.9","Blood RNA - T-reg [nTPM]":"25.8","Blood RNA - total PBMC [nTPM]":"15.5","Brain RNA - amygdala [nTPM]":"12.2","Brain RNA - basal ganglia [nTPM]":"12.6","Brain RNA - cerebellum [nTPM]":"12.4","Brain RNA - cerebral cortex [nTPM]":"13.1","Brain RNA - hippocampal formation [nTPM]":"12.2","Brain RNA - hypothalamus [nTPM]":"13.6","Brain RNA - medulla oblongata [nTPM]":"12.4","Brain RNA - midbrain [nTPM]":"14.7","Brain RNA - pons [nTPM]":"13.1","Brain RNA - spinal cord [nTPM]":"12.7","Brain RNA - thalamus [nTPM]":"14.0","Brain RNA - white matter [nTPM]":"13.1","Single Cell Type RNA - Adipocytes [nTPM]":"4.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.2","Single Cell Type RNA - Astrocytes [nTPM]":"7.2","Single Cell Type RNA - B-cells [nTPM]":"12.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"6.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"14.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"43.9","Single Cell Type RNA - dendritic cells [nTPM]":"6.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"80.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"13.7","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.1","Single Cell Type RNA - Endothelial cells [nTPM]":"8.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.8","Single Cell Type RNA - Erythroid cells [nTPM]":"17.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"31.6","Single Cell Type RNA - Fibroblasts [nTPM]":"16.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.9","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"81.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"27.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.5","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"41.3","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"3.5","Single Cell Type RNA - Langerhans cells [nTPM]":"3.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"9.3","Single Cell Type RNA - Macrophages [nTPM]":"3.5","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"2.6","Single Cell Type RNA - Muller glia cells [nTPM]":"7.1","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.7","Single Cell Type RNA - Paneth cells [nTPM]":"56.4","Single Cell Type RNA - Peritubular cells [nTPM]":"12.0","Single Cell Type RNA - Plasma cells [nTPM]":"30.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"79.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.1","Single Cell Type RNA - Spermatocytes [nTPM]":"8.2","Single Cell Type RNA - Spermatogonia [nTPM]":"9.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"30.2","Single Cell Type RNA - T-cells [nTPM]":"9.0","Single Cell Type RNA - Theca cells [nTPM]":"10.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"38.7","Single Cell Type RNA - Urothelial cells [nTPM]":"9.4"},{"Gene":"ALDH1A3","Gene synonym":["ALDH6","RALDH3"],"Ensembl":"ENSG00000184254","Gene description":"Aldehyde dehydrogenase 1 family member A3","Uniprot":["P47895"],"Chromosome":"15","Position":"100877714-100916626","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Microphthalmia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"prostate":"134.5","urinary bladder":"125.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"175.4","Endometrial stromal cells":"247.9","Leydig cells":"194.5","Prostatic glandular cells":"580.3","Urothelial cells":"468.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"prostate cancer":"80.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"363.3","HaCaT":"441.7","HBEC3-KT":"1096.9","hTERT-RPE1":"347.7","U-2197":"619.0","U-87 MG":"484.7","WM-115":"516.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"olfactory bulb":"4.5","spinal cord":"15.8"},"Antibody":["HPA046271","HPA064749"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA046271":"AB_10965992","HPA064749":"AB_2685344"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-3"},"Tissue RNA - adipose tissue [nTPM]":"83.7","Tissue RNA - adrenal gland [nTPM]":"11.4","Tissue RNA - amygdala [nTPM]":"3.0","Tissue RNA - appendix [nTPM]":"41.5","Tissue RNA - basal ganglia [nTPM]":"2.7","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"30.5","Tissue RNA - cerebellum [nTPM]":"4.7","Tissue RNA - cerebral cortex [nTPM]":"5.2","Tissue RNA - cervix [nTPM]":"37.1","Tissue RNA - choroid plexus [nTPM]":"16.2","Tissue RNA - colon [nTPM]":"16.6","Tissue RNA - duodenum [nTPM]":"15.0","Tissue RNA - endometrium 1 [nTPM]":"8.2","Tissue RNA - epididymis [nTPM]":"30.3","Tissue RNA - esophagus [nTPM]":"28.7","Tissue RNA - fallopian tube [nTPM]":"24.9","Tissue RNA - gallbladder [nTPM]":"17.0","Tissue RNA - heart muscle [nTPM]":"12.4","Tissue RNA - hippocampal formation [nTPM]":"3.1","Tissue RNA - hypothalamus [nTPM]":"1.9","Tissue RNA - kidney [nTPM]":"8.2","Tissue RNA - liver [nTPM]":"5.3","Tissue RNA - lung [nTPM]":"9.8","Tissue RNA - lymph node [nTPM]":"3.0","Tissue RNA - medulla oblongata [nTPM]":"4.8","Tissue RNA - midbrain [nTPM]":"3.4","Tissue RNA - ovary [nTPM]":"6.1","Tissue RNA - pancreas [nTPM]":"15.0","Tissue RNA - parathyroid gland [nTPM]":"9.0","Tissue RNA - pituitary gland [nTPM]":"7.5","Tissue RNA - placenta [nTPM]":"8.4","Tissue RNA - pons [nTPM]":"2.6","Tissue RNA - prostate [nTPM]":"134.5","Tissue RNA - rectum [nTPM]":"8.9","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"93.7","Tissue RNA - seminal vesicle [nTPM]":"49.3","Tissue RNA - skeletal muscle [nTPM]":"5.9","Tissue RNA - skin 1 [nTPM]":"3.9","Tissue RNA - small intestine [nTPM]":"25.2","Tissue RNA - smooth muscle [nTPM]":"40.8","Tissue RNA - spinal cord [nTPM]":"2.8","Tissue RNA - spleen [nTPM]":"3.1","Tissue RNA - stomach 1 [nTPM]":"12.8","Tissue RNA - testis [nTPM]":"16.6","Tissue RNA - thalamus [nTPM]":"3.3","Tissue RNA - thymus [nTPM]":"1.6","Tissue RNA - thyroid gland [nTPM]":"2.5","Tissue RNA - tongue [nTPM]":"6.9","Tissue RNA - tonsil [nTPM]":"15.7","Tissue RNA - urinary bladder [nTPM]":"125.1","Tissue RNA - vagina [nTPM]":"22.3","Tissue RNA - white matter [nTPM]":"3.9","Cell RNA - A-431 [nTPM]":"363.3","Cell RNA - A549 [nTPM]":"43.5","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"0.7","Cell RNA - ASC diff [nTPM]":"75.0","Cell RNA - ASC TERT1 [nTPM]":"32.8","Cell RNA - BEWO [nTPM]":"1.4","Cell RNA - BJ [nTPM]":"3.2","Cell RNA - BJ hTERT+ [nTPM]":"3.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.8","Cell RNA - CACO-2 [nTPM]":"1.0","Cell RNA - CAPAN-2 [nTPM]":"285.8","Cell RNA - Daudi [nTPM]":"2.6","Cell RNA - EFO-21 [nTPM]":"4.7","Cell RNA - fHDF\/TERT166 [nTPM]":"97.1","Cell RNA - GAMG [nTPM]":"55.7","Cell RNA - HaCaT [nTPM]":"441.7","Cell RNA - HAP1 [nTPM]":"8.8","Cell RNA - HBEC3-KT [nTPM]":"1096.9","Cell RNA - HBF TERT88 [nTPM]":"6.7","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"2.0","Cell RNA - HEL [nTPM]":"1.7","Cell RNA - HeLa [nTPM]":"20.1","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"25.5","Cell RNA - HL-60 [nTPM]":"1.4","Cell RNA - HMC-1 [nTPM]":"1.9","Cell RNA - HSkMC [nTPM]":"23.5","Cell RNA - hTCEpi [nTPM]":"29.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"24.4","Cell RNA - hTERT-HME1 [nTPM]":"4.5","Cell RNA - hTERT-RPE1 [nTPM]":"347.7","Cell RNA - HUVEC TERT2 [nTPM]":"4.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"2.4","Cell RNA - LHCN-M2 [nTPM]":"1.8","Cell RNA - MCF7 [nTPM]":"3.8","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"1.2","Cell RNA - NTERA-2 [nTPM]":"9.0","Cell RNA - OE19 [nTPM]":"9.6","Cell RNA - PC-3 [nTPM]":"316.3","Cell RNA - REH [nTPM]":"0.7","Cell RNA - RH-30 [nTPM]":"4.2","Cell RNA - RPMI-8226 [nTPM]":"2.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"283.6","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"25.4","Cell RNA - SiHa [nTPM]":"113.9","Cell RNA - SK-BR-3 [nTPM]":"94.9","Cell RNA - SK-MEL-30 [nTPM]":"33.3","Cell RNA - SuSa [nTPM]":"3.6","Cell RNA - T-47d [nTPM]":"9.3","Cell RNA - THP-1 [nTPM]":"3.2","Cell RNA - TIME [nTPM]":"58.3","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"1.0","Cell RNA - U-2197 [nTPM]":"619.0","Cell RNA - U-251 MG [nTPM]":"14.2","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"3.4","Cell RNA - U-698 [nTPM]":"1.5","Cell RNA - U-87 MG [nTPM]":"484.7","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"516.1","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.0","Brain RNA - basal ganglia [nTPM]":"2.7","Brain RNA - cerebellum [nTPM]":"4.7","Brain RNA - cerebral cortex [nTPM]":"5.2","Brain RNA - hippocampal formation [nTPM]":"3.1","Brain RNA - hypothalamus [nTPM]":"1.9","Brain RNA - medulla oblongata [nTPM]":"4.8","Brain RNA - midbrain [nTPM]":"3.4","Brain RNA - pons [nTPM]":"2.6","Brain RNA - spinal cord [nTPM]":"2.8","Brain RNA - thalamus [nTPM]":"3.3","Brain RNA - white matter [nTPM]":"3.9","Single Cell Type RNA - Adipocytes [nTPM]":"10.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"175.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"70.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"64.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"141.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"103.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"70.5","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"247.9","Single Cell Type RNA - Endothelial cells [nTPM]":"11.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.5","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"48.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.7","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.1","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.3","Single Cell Type RNA - Late spermatids [nTPM]":"8.5","Single Cell Type RNA - Leydig cells [nTPM]":"194.5","Single Cell Type RNA - Macrophages [nTPM]":"3.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"36.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"135.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"580.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"78.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.9","Single Cell Type RNA - T-cells [nTPM]":"2.0","Single Cell Type RNA - Theca cells [nTPM]":"1.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.8","Single Cell Type RNA - Urothelial cells [nTPM]":"468.7"},{"Gene":"ALDH3A2","Gene synonym":["ALDH10","FALDH","SLS"],"Ensembl":"ENSG00000072210","Gene description":"Aldehyde dehydrogenase 3 family member A2","Uniprot":["P51648"],"Chromosome":"17","Position":"19648136-19685760","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Ichthyosis","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"288.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"287.4","Squamous epithelial cells":"232.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"OE19":"285.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014769","CAB020692"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"32000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 61: Squamous epithelial cells - Keratinization","Subcellular main location":["Endoplasmic reticulum","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB020692":null,"HPA014769":"AB_1844728"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.85e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Tissue RNA - adipose tissue [nTPM]":"75.2","Tissue RNA - adrenal gland [nTPM]":"203.0","Tissue RNA - amygdala [nTPM]":"23.1","Tissue RNA - appendix [nTPM]":"15.2","Tissue RNA - basal ganglia [nTPM]":"32.5","Tissue RNA - bone marrow [nTPM]":"9.3","Tissue RNA - breast [nTPM]":"34.9","Tissue RNA - cerebellum [nTPM]":"24.8","Tissue RNA - cerebral cortex [nTPM]":"27.7","Tissue RNA - cervix [nTPM]":"49.4","Tissue RNA - choroid plexus [nTPM]":"71.7","Tissue RNA - colon [nTPM]":"49.6","Tissue RNA - duodenum [nTPM]":"68.1","Tissue RNA - endometrium 1 [nTPM]":"29.4","Tissue RNA - epididymis [nTPM]":"41.7","Tissue RNA - esophagus [nTPM]":"131.3","Tissue RNA - fallopian tube [nTPM]":"38.3","Tissue RNA - gallbladder [nTPM]":"70.5","Tissue RNA - heart muscle [nTPM]":"44.6","Tissue RNA - hippocampal formation [nTPM]":"29.0","Tissue RNA - hypothalamus [nTPM]":"27.9","Tissue RNA - kidney [nTPM]":"173.0","Tissue RNA - liver [nTPM]":"288.6","Tissue RNA - lung [nTPM]":"59.1","Tissue RNA - lymph node [nTPM]":"14.9","Tissue RNA - medulla oblongata [nTPM]":"23.3","Tissue RNA - midbrain [nTPM]":"26.3","Tissue RNA - ovary [nTPM]":"32.3","Tissue RNA - pancreas [nTPM]":"52.3","Tissue RNA - parathyroid gland [nTPM]":"40.6","Tissue RNA - pituitary gland [nTPM]":"21.9","Tissue RNA - placenta [nTPM]":"11.8","Tissue RNA - pons [nTPM]":"23.5","Tissue RNA - prostate [nTPM]":"75.0","Tissue RNA - rectum [nTPM]":"36.5","Tissue RNA - retina [nTPM]":"40.8","Tissue RNA - salivary gland [nTPM]":"61.7","Tissue RNA - seminal vesicle [nTPM]":"41.5","Tissue RNA - skeletal muscle [nTPM]":"53.0","Tissue RNA - skin 1 [nTPM]":"207.6","Tissue RNA - small intestine [nTPM]":"71.8","Tissue RNA - smooth muscle [nTPM]":"30.2","Tissue RNA - spinal cord [nTPM]":"25.1","Tissue RNA - spleen [nTPM]":"19.4","Tissue RNA - stomach 1 [nTPM]":"81.5","Tissue RNA - testis [nTPM]":"26.9","Tissue RNA - thalamus [nTPM]":"24.8","Tissue RNA - thymus [nTPM]":"23.0","Tissue RNA - thyroid gland [nTPM]":"75.1","Tissue RNA - tongue [nTPM]":"100.9","Tissue RNA - tonsil [nTPM]":"36.4","Tissue RNA - urinary bladder [nTPM]":"24.2","Tissue RNA - vagina [nTPM]":"40.5","Tissue RNA - white matter [nTPM]":"33.6","Cell RNA - A-431 [nTPM]":"27.7","Cell RNA - A549 [nTPM]":"147.0","Cell RNA - AF22 [nTPM]":"29.2","Cell RNA - AN3-CA [nTPM]":"58.5","Cell RNA - ASC diff [nTPM]":"88.7","Cell RNA - ASC TERT1 [nTPM]":"89.4","Cell RNA - BEWO [nTPM]":"19.1","Cell RNA - BJ [nTPM]":"12.3","Cell RNA - BJ hTERT+ [nTPM]":"29.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"27.6","Cell RNA - CACO-2 [nTPM]":"63.2","Cell RNA - CAPAN-2 [nTPM]":"52.5","Cell RNA - Daudi [nTPM]":"12.3","Cell RNA - EFO-21 [nTPM]":"35.9","Cell RNA - fHDF\/TERT166 [nTPM]":"50.5","Cell RNA - GAMG [nTPM]":"29.3","Cell RNA - HaCaT [nTPM]":"99.0","Cell RNA - HAP1 [nTPM]":"59.8","Cell RNA - HBEC3-KT [nTPM]":"125.2","Cell RNA - HBF TERT88 [nTPM]":"19.9","Cell RNA - HDLM-2 [nTPM]":"36.2","Cell RNA - HEK 293 [nTPM]":"42.5","Cell RNA - HEL [nTPM]":"5.3","Cell RNA - HeLa [nTPM]":"120.9","Cell RNA - Hep G2 [nTPM]":"142.8","Cell RNA - HHSteC [nTPM]":"12.2","Cell RNA - HL-60 [nTPM]":"30.6","Cell RNA - HMC-1 [nTPM]":"5.4","Cell RNA - HSkMC [nTPM]":"42.9","Cell RNA - hTCEpi [nTPM]":"137.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.9","Cell RNA - hTERT-HME1 [nTPM]":"12.2","Cell RNA - hTERT-RPE1 [nTPM]":"49.7","Cell RNA - HUVEC TERT2 [nTPM]":"49.2","Cell RNA - JURKAT [nTPM]":"25.5","Cell RNA - K-562 [nTPM]":"2.2","Cell RNA - Karpas-707 [nTPM]":"0.6","Cell RNA - LHCN-M2 [nTPM]":"37.3","Cell RNA - MCF7 [nTPM]":"45.3","Cell RNA - MOLT-4 [nTPM]":"0.7","Cell RNA - NB-4 [nTPM]":"25.2","Cell RNA - NTERA-2 [nTPM]":"32.3","Cell RNA - OE19 [nTPM]":"285.4","Cell RNA - PC-3 [nTPM]":"78.5","Cell RNA - REH [nTPM]":"38.6","Cell RNA - RH-30 [nTPM]":"64.1","Cell RNA - RPMI-8226 [nTPM]":"25.3","Cell RNA - RPTEC TERT1 [nTPM]":"17.5","Cell RNA - RT4 [nTPM]":"132.3","Cell RNA - SCLC-21H [nTPM]":"46.3","Cell RNA - SH-SY5Y [nTPM]":"30.4","Cell RNA - SiHa [nTPM]":"98.9","Cell RNA - SK-BR-3 [nTPM]":"38.4","Cell RNA - SK-MEL-30 [nTPM]":"35.3","Cell RNA - SuSa [nTPM]":"152.2","Cell RNA - T-47d [nTPM]":"78.1","Cell RNA - THP-1 [nTPM]":"35.0","Cell RNA - TIME [nTPM]":"46.7","Cell RNA - U-138 MG [nTPM]":"10.1","Cell RNA - U-2 OS [nTPM]":"28.7","Cell RNA - U-2197 [nTPM]":"68.8","Cell RNA - U-251 MG [nTPM]":"45.6","Cell RNA - U-266\/70 [nTPM]":"11.3","Cell RNA - U-266\/84 [nTPM]":"28.6","Cell RNA - U-698 [nTPM]":"15.5","Cell RNA - U-87 MG [nTPM]":"47.4","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"48.3","Blood RNA - basophil [nTPM]":"0.8","Blood RNA - classical monocyte [nTPM]":"21.1","Blood RNA - eosinophil [nTPM]":"17.5","Blood RNA - gdT-cell [nTPM]":"6.3","Blood RNA - intermediate monocyte [nTPM]":"18.3","Blood RNA - MAIT T-cell [nTPM]":"9.9","Blood RNA - memory B-cell [nTPM]":"5.2","Blood RNA - memory CD4 T-cell [nTPM]":"6.0","Blood RNA - memory CD8 T-cell [nTPM]":"6.1","Blood RNA - myeloid DC [nTPM]":"20.7","Blood RNA - naive B-cell [nTPM]":"4.9","Blood RNA - naive CD4 T-cell [nTPM]":"6.8","Blood RNA - naive CD8 T-cell [nTPM]":"6.3","Blood RNA - neutrophil [nTPM]":"2.2","Blood RNA - NK-cell [nTPM]":"15.0","Blood RNA - non-classical monocyte [nTPM]":"20.6","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"11.3","Blood RNA - total PBMC [nTPM]":"11.0","Brain RNA - amygdala [nTPM]":"23.1","Brain RNA - basal ganglia [nTPM]":"32.5","Brain RNA - cerebellum [nTPM]":"24.8","Brain RNA - cerebral cortex [nTPM]":"27.7","Brain RNA - hippocampal formation [nTPM]":"29.0","Brain RNA - hypothalamus [nTPM]":"27.9","Brain RNA - medulla oblongata [nTPM]":"23.3","Brain RNA - midbrain [nTPM]":"26.3","Brain RNA - pons [nTPM]":"23.5","Brain RNA - spinal cord [nTPM]":"25.1","Brain RNA - thalamus [nTPM]":"24.8","Brain RNA - white matter [nTPM]":"33.6","Single Cell Type RNA - Adipocytes [nTPM]":"22.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"176.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"86.5","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"13.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"57.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"143.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"85.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"287.4","Single Cell Type RNA - Bipolar cells [nTPM]":"15.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"54.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"105.8","Single Cell Type RNA - Club cells [nTPM]":"86.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.5","Single Cell Type RNA - dendritic cells [nTPM]":"8.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"48.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"43.0","Single Cell Type RNA - Ductal cells [nTPM]":"97.5","Single Cell Type RNA - Early spermatids [nTPM]":"79.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"47.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.4","Single Cell Type RNA - Endothelial cells [nTPM]":"19.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.2","Single Cell Type RNA - Erythroid cells [nTPM]":"8.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"30.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"52.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.6","Single Cell Type RNA - Fibroblasts [nTPM]":"39.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"87.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"36.9","Single Cell Type RNA - granulocytes [nTPM]":"29.7","Single Cell Type RNA - Granulosa cells [nTPM]":"34.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"116.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.6","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"27.7","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"21.7","Single Cell Type RNA - Langerhans cells [nTPM]":"15.1","Single Cell Type RNA - Late spermatids [nTPM]":"19.5","Single Cell Type RNA - Leydig cells [nTPM]":"55.9","Single Cell Type RNA - Macrophages [nTPM]":"23.5","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"25.7","Single Cell Type RNA - Muller glia cells [nTPM]":"105.9","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"29.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"43.9","Single Cell Type RNA - Paneth cells [nTPM]":"28.7","Single Cell Type RNA - Peritubular cells [nTPM]":"80.5","Single Cell Type RNA - Plasma cells [nTPM]":"28.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"104.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"90.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"119.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"59.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.4","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"70.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.1","Single Cell Type RNA - Spermatocytes [nTPM]":"15.5","Single Cell Type RNA - Spermatogonia [nTPM]":"24.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"232.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"90.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - T-cells [nTPM]":"13.2","Single Cell Type RNA - Theca cells [nTPM]":"29.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"46.0","Single Cell Type RNA - Urothelial cells [nTPM]":"51.4"},{"Gene":"ALDH4A1","Gene synonym":["ALDH4","P5CDh"],"Ensembl":"ENSG00000159423","Gene description":"Aldehyde dehydrogenase 4 family member A1","Uniprot":["P30038"],"Chromosome":"1","Position":"18871430-18902724","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Proline metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"200.4","liver":"436.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"78.0","Hepatocytes":"385.1","Proximal tubular cells":"279.4","Syncytiotrophoblasts":"86.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"72.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"83.7","SK-BR-3":"85.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004645","HPA006401","HPA072759"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"58000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB004645":"AB_425775","HPA006401":"AB_1844731","HPA072759":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.06e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-2"},"Tissue RNA - adipose tissue [nTPM]":"70.8","Tissue RNA - adrenal gland [nTPM]":"16.1","Tissue RNA - amygdala [nTPM]":"73.9","Tissue RNA - appendix [nTPM]":"3.9","Tissue RNA - basal ganglia [nTPM]":"88.9","Tissue RNA - bone marrow [nTPM]":"11.7","Tissue RNA - breast [nTPM]":"21.6","Tissue RNA - cerebellum [nTPM]":"73.8","Tissue RNA - cerebral cortex [nTPM]":"95.9","Tissue RNA - cervix [nTPM]":"12.6","Tissue RNA - choroid plexus [nTPM]":"106.5","Tissue RNA - colon [nTPM]":"6.8","Tissue RNA - duodenum [nTPM]":"1.6","Tissue RNA - endometrium 1 [nTPM]":"9.8","Tissue RNA - epididymis [nTPM]":"4.7","Tissue RNA - esophagus [nTPM]":"36.3","Tissue RNA - fallopian tube [nTPM]":"8.3","Tissue RNA - gallbladder [nTPM]":"5.5","Tissue RNA - heart muscle [nTPM]":"33.0","Tissue RNA - hippocampal formation [nTPM]":"68.2","Tissue RNA - hypothalamus [nTPM]":"73.8","Tissue RNA - kidney [nTPM]":"200.4","Tissue RNA - liver [nTPM]":"436.6","Tissue RNA - lung [nTPM]":"6.2","Tissue RNA - lymph node [nTPM]":"3.4","Tissue RNA - medulla oblongata [nTPM]":"72.9","Tissue RNA - midbrain [nTPM]":"82.8","Tissue RNA - ovary [nTPM]":"7.3","Tissue RNA - pancreas [nTPM]":"4.6","Tissue RNA - parathyroid gland [nTPM]":"23.0","Tissue RNA - pituitary gland [nTPM]":"9.7","Tissue RNA - placenta [nTPM]":"13.2","Tissue RNA - pons [nTPM]":"70.0","Tissue RNA - prostate [nTPM]":"29.5","Tissue RNA - rectum [nTPM]":"2.7","Tissue RNA - retina [nTPM]":"6.5","Tissue RNA - salivary gland [nTPM]":"9.1","Tissue RNA - seminal vesicle [nTPM]":"27.1","Tissue RNA - skeletal muscle [nTPM]":"74.2","Tissue RNA - skin 1 [nTPM]":"19.2","Tissue RNA - small intestine [nTPM]":"4.7","Tissue RNA - smooth muscle [nTPM]":"7.1","Tissue RNA - spinal cord [nTPM]":"65.6","Tissue RNA - spleen [nTPM]":"7.5","Tissue RNA - stomach 1 [nTPM]":"12.5","Tissue RNA - testis [nTPM]":"3.2","Tissue RNA - thalamus [nTPM]":"92.4","Tissue RNA - thymus [nTPM]":"11.7","Tissue RNA - thyroid gland [nTPM]":"7.1","Tissue RNA - tongue [nTPM]":"74.8","Tissue RNA - tonsil [nTPM]":"4.2","Tissue RNA - urinary bladder [nTPM]":"19.3","Tissue RNA - vagina [nTPM]":"16.8","Tissue RNA - white matter [nTPM]":"66.1","Cell RNA - A-431 [nTPM]":"12.7","Cell RNA - A549 [nTPM]":"17.8","Cell RNA - AF22 [nTPM]":"9.5","Cell RNA - AN3-CA [nTPM]":"29.2","Cell RNA - ASC diff [nTPM]":"40.0","Cell RNA - ASC TERT1 [nTPM]":"5.7","Cell RNA - BEWO [nTPM]":"25.2","Cell RNA - BJ [nTPM]":"13.1","Cell RNA - BJ hTERT+ [nTPM]":"7.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.5","Cell RNA - CACO-2 [nTPM]":"13.7","Cell RNA - CAPAN-2 [nTPM]":"8.9","Cell RNA - Daudi [nTPM]":"8.8","Cell RNA - EFO-21 [nTPM]":"16.6","Cell RNA - fHDF\/TERT166 [nTPM]":"15.6","Cell RNA - GAMG [nTPM]":"5.7","Cell RNA - HaCaT [nTPM]":"34.0","Cell RNA - HAP1 [nTPM]":"16.7","Cell RNA - HBEC3-KT [nTPM]":"35.4","Cell RNA - HBF TERT88 [nTPM]":"4.5","Cell RNA - HDLM-2 [nTPM]":"4.8","Cell RNA - HEK 293 [nTPM]":"15.9","Cell RNA - HEL [nTPM]":"5.9","Cell RNA - HeLa [nTPM]":"5.0","Cell RNA - Hep G2 [nTPM]":"83.7","Cell RNA - HHSteC [nTPM]":"12.6","Cell RNA - HL-60 [nTPM]":"4.4","Cell RNA - HMC-1 [nTPM]":"15.1","Cell RNA - HSkMC [nTPM]":"15.6","Cell RNA - hTCEpi [nTPM]":"19.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.5","Cell RNA - hTERT-HME1 [nTPM]":"6.6","Cell RNA - hTERT-RPE1 [nTPM]":"9.0","Cell RNA - HUVEC TERT2 [nTPM]":"13.5","Cell RNA - JURKAT [nTPM]":"14.0","Cell RNA - K-562 [nTPM]":"21.0","Cell RNA - Karpas-707 [nTPM]":"5.7","Cell RNA - LHCN-M2 [nTPM]":"8.1","Cell RNA - MCF7 [nTPM]":"32.3","Cell RNA - MOLT-4 [nTPM]":"4.3","Cell RNA - NB-4 [nTPM]":"20.2","Cell RNA - NTERA-2 [nTPM]":"4.7","Cell RNA - OE19 [nTPM]":"26.0","Cell RNA - PC-3 [nTPM]":"10.1","Cell RNA - REH [nTPM]":"27.9","Cell RNA - RH-30 [nTPM]":"8.4","Cell RNA - RPMI-8226 [nTPM]":"10.0","Cell RNA - RPTEC TERT1 [nTPM]":"12.1","Cell RNA - RT4 [nTPM]":"32.0","Cell RNA - SCLC-21H [nTPM]":"19.6","Cell RNA - SH-SY5Y [nTPM]":"7.6","Cell RNA - SiHa [nTPM]":"21.9","Cell RNA - SK-BR-3 [nTPM]":"85.0","Cell RNA - SK-MEL-30 [nTPM]":"16.1","Cell RNA - SuSa [nTPM]":"14.7","Cell RNA - T-47d [nTPM]":"38.7","Cell RNA - THP-1 [nTPM]":"6.3","Cell RNA - TIME [nTPM]":"11.3","Cell RNA - U-138 MG [nTPM]":"10.2","Cell RNA - U-2 OS [nTPM]":"14.0","Cell RNA - U-2197 [nTPM]":"12.2","Cell RNA - U-251 MG [nTPM]":"4.5","Cell RNA - U-266\/70 [nTPM]":"7.1","Cell RNA - U-266\/84 [nTPM]":"17.9","Cell RNA - U-698 [nTPM]":"2.5","Cell RNA - U-87 MG [nTPM]":"3.4","Cell RNA - U-937 [nTPM]":"33.7","Cell RNA - WM-115 [nTPM]":"13.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.7","Blood RNA - eosinophil [nTPM]":"1.5","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"3.6","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"4.4","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"2.0","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"1.5","Brain RNA - amygdala [nTPM]":"73.9","Brain RNA - basal ganglia [nTPM]":"88.9","Brain RNA - cerebellum [nTPM]":"73.8","Brain RNA - cerebral cortex [nTPM]":"95.9","Brain RNA - hippocampal formation [nTPM]":"68.2","Brain RNA - hypothalamus [nTPM]":"73.8","Brain RNA - medulla oblongata [nTPM]":"72.9","Brain RNA - midbrain [nTPM]":"82.8","Brain RNA - pons [nTPM]":"70.0","Brain RNA - spinal cord [nTPM]":"65.6","Brain RNA - thalamus [nTPM]":"92.4","Brain RNA - white matter [nTPM]":"66.1","Single Cell Type RNA - Adipocytes [nTPM]":"2.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.8","Single Cell Type RNA - Astrocytes [nTPM]":"27.1","Single Cell Type RNA - B-cells [nTPM]":"4.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.6","Single Cell Type RNA - Bipolar cells [nTPM]":"3.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"20.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"34.3","Single Cell Type RNA - Club cells [nTPM]":"2.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"46.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"78.0","Single Cell Type RNA - dendritic cells [nTPM]":"2.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"46.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.7","Single Cell Type RNA - Endothelial cells [nTPM]":"3.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"32.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.6","Single Cell Type RNA - Fibroblasts [nTPM]":"3.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.9","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"2.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.4","Single Cell Type RNA - Hepatocytes [nTPM]":"385.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.8","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.6","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"17.2","Single Cell Type RNA - Langerhans cells [nTPM]":"1.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"4.7","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"10.9","Single Cell Type RNA - Muller glia cells [nTPM]":"14.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.5","Single Cell Type RNA - Paneth cells [nTPM]":"1.8","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"4.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"279.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.7","Single Cell Type RNA - Spermatocytes [nTPM]":"2.2","Single Cell Type RNA - Spermatogonia [nTPM]":"3.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"86.6","Single Cell Type RNA - T-cells [nTPM]":"2.6","Single Cell Type RNA - Theca cells [nTPM]":"4.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.0","Single Cell Type RNA - Urothelial cells [nTPM]":"9.5"},{"Gene":"ALDH5A1","Gene synonym":["SSADH","SSDH"],"Ensembl":"ENSG00000112294","Gene description":"Aldehyde dehydrogenase 5 family member A1","Uniprot":["P51649"],"Chromosome":"6","Position":"24494867-24537207","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"98.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"90.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"136.6","U-698":"173.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029715","HPA029716"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"50000","Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA029715":"AB_10599994","HPA029716":"AB_10601876"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.61e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.20e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.68e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.4","Tissue RNA - adrenal gland [nTPM]":"6.1","Tissue RNA - amygdala [nTPM]":"27.8","Tissue RNA - appendix [nTPM]":"5.9","Tissue RNA - basal ganglia [nTPM]":"28.9","Tissue RNA - bone marrow [nTPM]":"4.4","Tissue RNA - breast [nTPM]":"5.2","Tissue RNA - cerebellum [nTPM]":"25.0","Tissue RNA - cerebral cortex [nTPM]":"32.7","Tissue RNA - cervix [nTPM]":"5.4","Tissue RNA - choroid plexus [nTPM]":"18.8","Tissue RNA - colon [nTPM]":"8.5","Tissue RNA - duodenum [nTPM]":"11.8","Tissue RNA - endometrium 1 [nTPM]":"4.8","Tissue RNA - epididymis [nTPM]":"3.7","Tissue RNA - esophagus [nTPM]":"7.3","Tissue RNA - fallopian tube [nTPM]":"19.0","Tissue RNA - gallbladder [nTPM]":"5.1","Tissue RNA - heart muscle [nTPM]":"14.5","Tissue RNA - hippocampal formation [nTPM]":"26.5","Tissue RNA - hypothalamus [nTPM]":"32.8","Tissue RNA - kidney [nTPM]":"27.8","Tissue RNA - liver [nTPM]":"98.8","Tissue RNA - lung [nTPM]":"6.4","Tissue RNA - lymph node [nTPM]":"13.6","Tissue RNA - medulla oblongata [nTPM]":"26.7","Tissue RNA - midbrain [nTPM]":"35.0","Tissue RNA - ovary [nTPM]":"7.3","Tissue RNA - pancreas [nTPM]":"8.2","Tissue RNA - parathyroid gland [nTPM]":"19.4","Tissue RNA - pituitary gland [nTPM]":"5.8","Tissue RNA - placenta [nTPM]":"2.4","Tissue RNA - pons [nTPM]":"27.3","Tissue RNA - prostate [nTPM]":"8.2","Tissue RNA - rectum [nTPM]":"7.1","Tissue RNA - retina [nTPM]":"11.0","Tissue RNA - salivary gland [nTPM]":"5.2","Tissue RNA - seminal vesicle [nTPM]":"5.2","Tissue RNA - skeletal muscle [nTPM]":"57.9","Tissue RNA - skin 1 [nTPM]":"9.5","Tissue RNA - small intestine [nTPM]":"8.0","Tissue RNA - smooth muscle [nTPM]":"3.1","Tissue RNA - spinal cord [nTPM]":"29.4","Tissue RNA - spleen [nTPM]":"6.8","Tissue RNA - stomach 1 [nTPM]":"7.7","Tissue RNA - testis [nTPM]":"4.5","Tissue RNA - thalamus [nTPM]":"34.0","Tissue RNA - thymus [nTPM]":"26.8","Tissue RNA - thyroid gland [nTPM]":"17.0","Tissue RNA - tongue [nTPM]":"33.8","Tissue RNA - tonsil [nTPM]":"12.9","Tissue RNA - urinary bladder [nTPM]":"6.7","Tissue RNA - vagina [nTPM]":"8.4","Tissue RNA - white matter [nTPM]":"24.9","Cell RNA - A-431 [nTPM]":"11.5","Cell RNA - A549 [nTPM]":"9.3","Cell RNA - AF22 [nTPM]":"6.5","Cell RNA - AN3-CA [nTPM]":"10.1","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"11.7","Cell RNA - BJ [nTPM]":"0.8","Cell RNA - BJ hTERT+ [nTPM]":"2.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.6","Cell RNA - CACO-2 [nTPM]":"35.1","Cell RNA - CAPAN-2 [nTPM]":"2.5","Cell RNA - Daudi [nTPM]":"136.6","Cell RNA - EFO-21 [nTPM]":"21.1","Cell RNA - fHDF\/TERT166 [nTPM]":"1.0","Cell RNA - GAMG [nTPM]":"2.2","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"10.5","Cell RNA - HBEC3-KT [nTPM]":"1.3","Cell RNA - HBF TERT88 [nTPM]":"1.5","Cell RNA - HDLM-2 [nTPM]":"14.7","Cell RNA - HEK 293 [nTPM]":"20.2","Cell RNA - HEL [nTPM]":"20.7","Cell RNA - HeLa [nTPM]":"5.9","Cell RNA - Hep G2 [nTPM]":"42.4","Cell RNA - HHSteC [nTPM]":"1.6","Cell RNA - HL-60 [nTPM]":"32.2","Cell RNA - HMC-1 [nTPM]":"2.7","Cell RNA - HSkMC [nTPM]":"1.0","Cell RNA - hTCEpi [nTPM]":"4.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"7.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"34.7","Cell RNA - K-562 [nTPM]":"10.4","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"1.8","Cell RNA - MCF7 [nTPM]":"23.3","Cell RNA - MOLT-4 [nTPM]":"40.4","Cell RNA - NB-4 [nTPM]":"19.0","Cell RNA - NTERA-2 [nTPM]":"2.7","Cell RNA - OE19 [nTPM]":"18.4","Cell RNA - PC-3 [nTPM]":"5.5","Cell RNA - REH [nTPM]":"46.1","Cell RNA - RH-30 [nTPM]":"1.4","Cell RNA - RPMI-8226 [nTPM]":"1.3","Cell RNA - RPTEC TERT1 [nTPM]":"7.7","Cell RNA - RT4 [nTPM]":"19.6","Cell RNA - SCLC-21H [nTPM]":"11.7","Cell RNA - SH-SY5Y [nTPM]":"10.5","Cell RNA - SiHa [nTPM]":"12.1","Cell RNA - SK-BR-3 [nTPM]":"1.2","Cell RNA - SK-MEL-30 [nTPM]":"13.2","Cell RNA - SuSa [nTPM]":"2.8","Cell RNA - T-47d [nTPM]":"19.4","Cell RNA - THP-1 [nTPM]":"17.5","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"1.1","Cell RNA - U-2 OS [nTPM]":"6.7","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"7.1","Cell RNA - U-266\/70 [nTPM]":"19.4","Cell RNA - U-266\/84 [nTPM]":"32.2","Cell RNA - U-698 [nTPM]":"173.7","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"9.8","Cell RNA - WM-115 [nTPM]":"1.4","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"1.9","Blood RNA - memory B-cell [nTPM]":"2.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.4","Blood RNA - memory CD8 T-cell [nTPM]":"1.5","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"2.0","Blood RNA - naive CD4 T-cell [nTPM]":"3.8","Blood RNA - naive CD8 T-cell [nTPM]":"3.4","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"2.4","Blood RNA - T-reg [nTPM]":"0.9","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"27.8","Brain RNA - basal ganglia [nTPM]":"28.9","Brain RNA - cerebellum [nTPM]":"25.0","Brain RNA - cerebral cortex [nTPM]":"32.7","Brain RNA - hippocampal formation [nTPM]":"26.5","Brain RNA - hypothalamus [nTPM]":"32.8","Brain RNA - medulla oblongata [nTPM]":"26.7","Brain RNA - midbrain [nTPM]":"35.0","Brain RNA - pons [nTPM]":"27.3","Brain RNA - spinal cord [nTPM]":"29.4","Brain RNA - thalamus [nTPM]":"34.0","Brain RNA - white matter [nTPM]":"24.9","Single Cell Type RNA - Adipocytes [nTPM]":"2.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.3","Single Cell Type RNA - Astrocytes [nTPM]":"14.0","Single Cell Type RNA - B-cells [nTPM]":"9.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"12.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"34.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"9.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.1","Single Cell Type RNA - dendritic cells [nTPM]":"7.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.0","Single Cell Type RNA - Endothelial cells [nTPM]":"3.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"16.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.2","Single Cell Type RNA - Fibroblasts [nTPM]":"3.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.4","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"13.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"90.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.9","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"32.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.7","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.8","Single Cell Type RNA - Langerhans cells [nTPM]":"1.8","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"1.7","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"11.8","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.3","Single Cell Type RNA - Paneth cells [nTPM]":"7.7","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"12.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"26.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.7","Single Cell Type RNA - Spermatogonia [nTPM]":"6.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - T-cells [nTPM]":"5.4","Single Cell Type RNA - Theca cells [nTPM]":"8.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.0","Single Cell Type RNA - Urothelial cells [nTPM]":"13.1"},{"Gene":"ALDH6A1","Gene synonym":["MMSDH"],"Ensembl":"ENSG00000119711","Gene description":"Aldehyde dehydrogenase 6 family member A1","Uniprot":["Q02252"],"Chromosome":"14","Position":"74056847-74084492","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"kidney":"379.1","liver":"367.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"201.5","Hepatocytes":"523.6","Proximal tubular cells":"962.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"43.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"43.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"T-47d":"57.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029072","HPA029073","HPA029074","HPA029075"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"37000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA029072":"AB_10599176","HPA029073":"AB_10601877","HPA029074":"AB_10601000","HPA029075":"AB_10602005"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.22e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.00e-15"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Tissue RNA - adipose tissue [nTPM]":"38.7","Tissue RNA - adrenal gland [nTPM]":"14.7","Tissue RNA - amygdala [nTPM]":"58.6","Tissue RNA - appendix [nTPM]":"4.8","Tissue RNA - basal ganglia [nTPM]":"66.0","Tissue RNA - bone marrow [nTPM]":"3.3","Tissue RNA - breast [nTPM]":"14.4","Tissue RNA - cerebellum [nTPM]":"58.8","Tissue RNA - cerebral cortex [nTPM]":"59.3","Tissue RNA - cervix [nTPM]":"17.3","Tissue RNA - choroid plexus [nTPM]":"61.4","Tissue RNA - colon [nTPM]":"15.2","Tissue RNA - duodenum [nTPM]":"26.6","Tissue RNA - endometrium 1 [nTPM]":"11.4","Tissue RNA - epididymis [nTPM]":"9.8","Tissue RNA - esophagus [nTPM]":"9.8","Tissue RNA - fallopian tube [nTPM]":"12.8","Tissue RNA - gallbladder [nTPM]":"9.4","Tissue RNA - heart muscle [nTPM]":"40.3","Tissue RNA - hippocampal formation [nTPM]":"51.0","Tissue RNA - hypothalamus [nTPM]":"54.0","Tissue RNA - kidney [nTPM]":"379.1","Tissue RNA - liver [nTPM]":"367.1","Tissue RNA - lung [nTPM]":"9.4","Tissue RNA - lymph node [nTPM]":"5.1","Tissue RNA - medulla oblongata [nTPM]":"63.3","Tissue RNA - midbrain [nTPM]":"54.0","Tissue RNA - ovary [nTPM]":"28.3","Tissue RNA - pancreas [nTPM]":"23.4","Tissue RNA - parathyroid gland [nTPM]":"37.0","Tissue RNA - pituitary gland [nTPM]":"6.6","Tissue RNA - placenta [nTPM]":"7.6","Tissue RNA - pons [nTPM]":"55.6","Tissue RNA - prostate [nTPM]":"25.4","Tissue RNA - rectum [nTPM]":"15.8","Tissue RNA - retina [nTPM]":"15.2","Tissue RNA - salivary gland [nTPM]":"19.8","Tissue RNA - seminal vesicle [nTPM]":"16.1","Tissue RNA - skeletal muscle [nTPM]":"27.5","Tissue RNA - skin 1 [nTPM]":"6.2","Tissue RNA - small intestine [nTPM]":"23.4","Tissue RNA - smooth muscle [nTPM]":"9.0","Tissue RNA - spinal cord [nTPM]":"56.4","Tissue RNA - spleen [nTPM]":"5.4","Tissue RNA - stomach 1 [nTPM]":"24.0","Tissue RNA - testis [nTPM]":"17.1","Tissue RNA - thalamus [nTPM]":"69.8","Tissue RNA - thymus [nTPM]":"5.7","Tissue RNA - thyroid gland [nTPM]":"28.3","Tissue RNA - tongue [nTPM]":"34.8","Tissue RNA - tonsil [nTPM]":"5.3","Tissue RNA - urinary bladder [nTPM]":"11.4","Tissue RNA - vagina [nTPM]":"7.0","Tissue RNA - white matter [nTPM]":"62.6","Cell RNA - A-431 [nTPM]":"8.9","Cell RNA - A549 [nTPM]":"7.8","Cell RNA - AF22 [nTPM]":"11.0","Cell RNA - AN3-CA [nTPM]":"23.5","Cell RNA - ASC diff [nTPM]":"39.3","Cell RNA - ASC TERT1 [nTPM]":"19.2","Cell RNA - BEWO [nTPM]":"17.5","Cell RNA - BJ [nTPM]":"6.3","Cell RNA - BJ hTERT+ [nTPM]":"11.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.5","Cell RNA - CACO-2 [nTPM]":"17.3","Cell RNA - CAPAN-2 [nTPM]":"10.2","Cell RNA - Daudi [nTPM]":"10.5","Cell RNA - EFO-21 [nTPM]":"13.6","Cell RNA - fHDF\/TERT166 [nTPM]":"13.5","Cell RNA - GAMG [nTPM]":"5.3","Cell RNA - HaCaT [nTPM]":"4.8","Cell RNA - HAP1 [nTPM]":"24.9","Cell RNA - HBEC3-KT [nTPM]":"7.0","Cell RNA - HBF TERT88 [nTPM]":"14.5","Cell RNA - HDLM-2 [nTPM]":"9.5","Cell RNA - HEK 293 [nTPM]":"3.5","Cell RNA - HEL [nTPM]":"5.1","Cell RNA - HeLa [nTPM]":"8.0","Cell RNA - Hep G2 [nTPM]":"19.2","Cell RNA - HHSteC [nTPM]":"45.0","Cell RNA - HL-60 [nTPM]":"2.7","Cell RNA - HMC-1 [nTPM]":"2.4","Cell RNA - HSkMC [nTPM]":"28.2","Cell RNA - hTCEpi [nTPM]":"12.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.7","Cell RNA - hTERT-HME1 [nTPM]":"20.7","Cell RNA - hTERT-RPE1 [nTPM]":"17.0","Cell RNA - HUVEC TERT2 [nTPM]":"12.0","Cell RNA - JURKAT [nTPM]":"23.7","Cell RNA - K-562 [nTPM]":"8.1","Cell RNA - Karpas-707 [nTPM]":"14.7","Cell RNA - LHCN-M2 [nTPM]":"4.6","Cell RNA - MCF7 [nTPM]":"36.2","Cell RNA - MOLT-4 [nTPM]":"7.6","Cell RNA - NB-4 [nTPM]":"4.0","Cell RNA - NTERA-2 [nTPM]":"8.7","Cell RNA - OE19 [nTPM]":"32.6","Cell RNA - PC-3 [nTPM]":"5.2","Cell RNA - REH [nTPM]":"15.1","Cell RNA - RH-30 [nTPM]":"11.2","Cell RNA - RPMI-8226 [nTPM]":"14.6","Cell RNA - RPTEC TERT1 [nTPM]":"9.2","Cell RNA - RT4 [nTPM]":"5.8","Cell RNA - SCLC-21H [nTPM]":"4.4","Cell RNA - SH-SY5Y [nTPM]":"7.0","Cell RNA - SiHa [nTPM]":"21.0","Cell RNA - SK-BR-3 [nTPM]":"21.9","Cell RNA - SK-MEL-30 [nTPM]":"5.7","Cell RNA - SuSa [nTPM]":"18.0","Cell RNA - T-47d [nTPM]":"57.5","Cell RNA - THP-1 [nTPM]":"9.6","Cell RNA - TIME [nTPM]":"3.8","Cell RNA - U-138 MG [nTPM]":"7.4","Cell RNA - U-2 OS [nTPM]":"9.0","Cell RNA - U-2197 [nTPM]":"11.7","Cell RNA - U-251 MG [nTPM]":"2.4","Cell RNA - U-266\/70 [nTPM]":"9.3","Cell RNA - U-266\/84 [nTPM]":"18.9","Cell RNA - U-698 [nTPM]":"10.2","Cell RNA - U-87 MG [nTPM]":"9.9","Cell RNA - U-937 [nTPM]":"3.2","Cell RNA - WM-115 [nTPM]":"7.3","Blood RNA - basophil [nTPM]":"29.1","Blood RNA - classical monocyte [nTPM]":"6.2","Blood RNA - eosinophil [nTPM]":"43.2","Blood RNA - gdT-cell [nTPM]":"6.9","Blood RNA - intermediate monocyte [nTPM]":"4.8","Blood RNA - MAIT T-cell [nTPM]":"10.6","Blood RNA - memory B-cell [nTPM]":"7.2","Blood RNA - memory CD4 T-cell [nTPM]":"7.8","Blood RNA - memory CD8 T-cell [nTPM]":"8.4","Blood RNA - myeloid DC [nTPM]":"9.2","Blood RNA - naive B-cell [nTPM]":"6.1","Blood RNA - naive CD4 T-cell [nTPM]":"9.9","Blood RNA - naive CD8 T-cell [nTPM]":"7.0","Blood RNA - neutrophil [nTPM]":"2.4","Blood RNA - NK-cell [nTPM]":"9.7","Blood RNA - non-classical monocyte [nTPM]":"4.2","Blood RNA - plasmacytoid DC [nTPM]":"5.3","Blood RNA - T-reg [nTPM]":"6.1","Blood RNA - total PBMC [nTPM]":"4.9","Brain RNA - amygdala [nTPM]":"58.6","Brain RNA - basal ganglia [nTPM]":"66.0","Brain RNA - cerebellum [nTPM]":"58.8","Brain RNA - cerebral cortex [nTPM]":"59.3","Brain RNA - hippocampal formation [nTPM]":"51.0","Brain RNA - hypothalamus [nTPM]":"54.0","Brain RNA - medulla oblongata [nTPM]":"63.3","Brain RNA - midbrain [nTPM]":"54.0","Brain RNA - pons [nTPM]":"55.6","Brain RNA - spinal cord [nTPM]":"56.4","Brain RNA - thalamus [nTPM]":"69.8","Brain RNA - white matter [nTPM]":"62.6","Single Cell Type RNA - Adipocytes [nTPM]":"15.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"60.4","Single Cell Type RNA - Astrocytes [nTPM]":"24.5","Single Cell Type RNA - B-cells [nTPM]":"11.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"26.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"20.5","Single Cell Type RNA - Bipolar cells [nTPM]":"20.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"28.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"81.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"67.2","Single Cell Type RNA - Club cells [nTPM]":"22.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"66.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"31.0","Single Cell Type RNA - dendritic cells [nTPM]":"7.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"201.5","Single Cell Type RNA - Ductal cells [nTPM]":"11.6","Single Cell Type RNA - Early spermatids [nTPM]":"23.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"26.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"27.5","Single Cell Type RNA - Endothelial cells [nTPM]":"27.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.9","Single Cell Type RNA - Erythroid cells [nTPM]":"28.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.8","Single Cell Type RNA - Fibroblasts [nTPM]":"25.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"34.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"90.2","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"27.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"87.4","Single Cell Type RNA - Hepatocytes [nTPM]":"523.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.7","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"39.3","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"26.5","Single Cell Type RNA - Langerhans cells [nTPM]":"8.9","Single Cell Type RNA - Late spermatids [nTPM]":"19.0","Single Cell Type RNA - Leydig cells [nTPM]":"28.9","Single Cell Type RNA - Macrophages [nTPM]":"13.4","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"15.8","Single Cell Type RNA - Muller glia cells [nTPM]":"98.5","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"23.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.1","Single Cell Type RNA - Paneth cells [nTPM]":"16.3","Single Cell Type RNA - Peritubular cells [nTPM]":"48.2","Single Cell Type RNA - Plasma cells [nTPM]":"8.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"27.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"55.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"962.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"25.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.9","Single Cell Type RNA - Spermatocytes [nTPM]":"11.0","Single Cell Type RNA - Spermatogonia [nTPM]":"4.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"30.6","Single Cell Type RNA - T-cells [nTPM]":"11.0","Single Cell Type RNA - Theca cells [nTPM]":"10.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"35.7","Single Cell Type RNA - Urothelial cells [nTPM]":"17.2"},{"Gene":"ALDH7A1","Gene synonym":["ATQ1","EPD","PDE"],"Ensembl":"ENSG00000164904","Gene description":"Aldehyde dehydrogenase 7 family member A1","Uniprot":["P49419"],"Chromosome":"5","Position":"126531200-126595362","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"162.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"414.1","Proximal tubular cells":"302.1","Syncytiotrophoblasts":"222.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"6.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"6.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HBEC3-KT":"256.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023296","HPA053675"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"430000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 23: AN3-CA - Transcription regulation","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA023296":"AB_1844738","HPA053675":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.08e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-2"},"Tissue RNA - adipose tissue [nTPM]":"23.7","Tissue RNA - adrenal gland [nTPM]":"38.3","Tissue RNA - amygdala [nTPM]":"46.6","Tissue RNA - appendix [nTPM]":"9.1","Tissue RNA - basal ganglia [nTPM]":"47.6","Tissue RNA - bone marrow [nTPM]":"1.8","Tissue RNA - breast [nTPM]":"47.1","Tissue RNA - cerebellum [nTPM]":"43.7","Tissue RNA - cerebral cortex [nTPM]":"45.8","Tissue RNA - cervix [nTPM]":"32.7","Tissue RNA - choroid plexus [nTPM]":"40.7","Tissue RNA - colon [nTPM]":"29.5","Tissue RNA - duodenum [nTPM]":"23.7","Tissue RNA - endometrium 1 [nTPM]":"25.1","Tissue RNA - epididymis [nTPM]":"8.8","Tissue RNA - esophagus [nTPM]":"35.9","Tissue RNA - fallopian tube [nTPM]":"28.8","Tissue RNA - gallbladder [nTPM]":"19.1","Tissue RNA - heart muscle [nTPM]":"27.9","Tissue RNA - hippocampal formation [nTPM]":"44.7","Tissue RNA - hypothalamus [nTPM]":"43.2","Tissue RNA - kidney [nTPM]":"115.1","Tissue RNA - liver [nTPM]":"162.2","Tissue RNA - lung [nTPM]":"15.7","Tissue RNA - lymph node [nTPM]":"8.6","Tissue RNA - medulla oblongata [nTPM]":"43.1","Tissue RNA - midbrain [nTPM]":"43.5","Tissue RNA - ovary [nTPM]":"65.3","Tissue RNA - pancreas [nTPM]":"27.0","Tissue RNA - parathyroid gland [nTPM]":"34.0","Tissue RNA - pituitary gland [nTPM]":"8.8","Tissue RNA - placenta [nTPM]":"44.9","Tissue RNA - pons [nTPM]":"42.6","Tissue RNA - prostate [nTPM]":"42.0","Tissue RNA - rectum [nTPM]":"27.4","Tissue RNA - retina [nTPM]":"19.7","Tissue RNA - salivary gland [nTPM]":"40.6","Tissue RNA - seminal vesicle [nTPM]":"27.9","Tissue RNA - skeletal muscle [nTPM]":"12.2","Tissue RNA - skin 1 [nTPM]":"29.4","Tissue RNA - small intestine [nTPM]":"21.0","Tissue RNA - smooth muscle [nTPM]":"23.6","Tissue RNA - spinal cord [nTPM]":"44.8","Tissue RNA - spleen [nTPM]":"7.0","Tissue RNA - stomach 1 [nTPM]":"23.6","Tissue RNA - testis [nTPM]":"12.3","Tissue RNA - thalamus [nTPM]":"44.0","Tissue RNA - thymus [nTPM]":"18.3","Tissue RNA - thyroid gland [nTPM]":"47.6","Tissue RNA - tongue [nTPM]":"26.5","Tissue RNA - tonsil [nTPM]":"17.1","Tissue RNA - urinary bladder [nTPM]":"18.1","Tissue RNA - vagina [nTPM]":"20.9","Tissue RNA - white matter [nTPM]":"45.2","Cell RNA - A-431 [nTPM]":"64.9","Cell RNA - A549 [nTPM]":"41.9","Cell RNA - AF22 [nTPM]":"116.6","Cell RNA - AN3-CA [nTPM]":"193.4","Cell RNA - ASC diff [nTPM]":"95.5","Cell RNA - ASC TERT1 [nTPM]":"56.4","Cell RNA - BEWO [nTPM]":"147.8","Cell RNA - BJ [nTPM]":"76.1","Cell RNA - BJ hTERT+ [nTPM]":"93.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"86.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"110.5","Cell RNA - CACO-2 [nTPM]":"118.6","Cell RNA - CAPAN-2 [nTPM]":"60.7","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"75.5","Cell RNA - fHDF\/TERT166 [nTPM]":"60.0","Cell RNA - GAMG [nTPM]":"36.1","Cell RNA - HaCaT [nTPM]":"47.1","Cell RNA - HAP1 [nTPM]":"36.5","Cell RNA - HBEC3-KT [nTPM]":"256.2","Cell RNA - HBF TERT88 [nTPM]":"78.8","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"44.6","Cell RNA - HEL [nTPM]":"12.3","Cell RNA - HeLa [nTPM]":"63.1","Cell RNA - Hep G2 [nTPM]":"102.1","Cell RNA - HHSteC [nTPM]":"46.3","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"69.0","Cell RNA - hTCEpi [nTPM]":"59.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"67.3","Cell RNA - hTERT-HME1 [nTPM]":"47.7","Cell RNA - hTERT-RPE1 [nTPM]":"64.2","Cell RNA - HUVEC TERT2 [nTPM]":"70.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"77.1","Cell RNA - MCF7 [nTPM]":"42.1","Cell RNA - MOLT-4 [nTPM]":"2.6","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"79.4","Cell RNA - OE19 [nTPM]":"47.5","Cell RNA - PC-3 [nTPM]":"35.2","Cell RNA - REH [nTPM]":"38.9","Cell RNA - RH-30 [nTPM]":"131.8","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"81.2","Cell RNA - RT4 [nTPM]":"48.4","Cell RNA - SCLC-21H [nTPM]":"39.4","Cell RNA - SH-SY5Y [nTPM]":"47.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"41.1","Cell RNA - SK-MEL-30 [nTPM]":"44.7","Cell RNA - SuSa [nTPM]":"89.0","Cell RNA - T-47d [nTPM]":"75.2","Cell RNA - THP-1 [nTPM]":"2.7","Cell RNA - TIME [nTPM]":"86.1","Cell RNA - U-138 MG [nTPM]":"24.8","Cell RNA - U-2 OS [nTPM]":"75.6","Cell RNA - U-2197 [nTPM]":"28.8","Cell RNA - U-251 MG [nTPM]":"53.1","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"13.4","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"40.6","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"1.8","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"6.4","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"46.6","Brain RNA - basal ganglia [nTPM]":"47.6","Brain RNA - cerebellum [nTPM]":"43.7","Brain RNA - cerebral cortex [nTPM]":"45.8","Brain RNA - hippocampal formation [nTPM]":"44.7","Brain RNA - hypothalamus [nTPM]":"43.2","Brain RNA - medulla oblongata [nTPM]":"43.1","Brain RNA - midbrain [nTPM]":"43.5","Brain RNA - pons [nTPM]":"42.6","Brain RNA - spinal cord [nTPM]":"44.8","Brain RNA - thalamus [nTPM]":"44.0","Brain RNA - white matter [nTPM]":"45.2","Single Cell Type RNA - Adipocytes [nTPM]":"17.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.3","Single Cell Type RNA - Astrocytes [nTPM]":"99.3","Single Cell Type RNA - B-cells [nTPM]":"5.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"25.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"59.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"110.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"87.0","Single Cell Type RNA - Bipolar cells [nTPM]":"23.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"40.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"91.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"39.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"43.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"42.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"414.1","Single Cell Type RNA - dendritic cells [nTPM]":"3.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"76.3","Single Cell Type RNA - Ductal cells [nTPM]":"43.5","Single Cell Type RNA - Early spermatids [nTPM]":"31.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"44.3","Single Cell Type RNA - Endothelial cells [nTPM]":"19.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.7","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"107.8","Single Cell Type RNA - Fibroblasts [nTPM]":"34.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"27.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.4","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"50.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.9","Single Cell Type RNA - Hepatocytes [nTPM]":"74.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"51.1","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"25.9","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"9.4","Single Cell Type RNA - Langerhans cells [nTPM]":"7.6","Single Cell Type RNA - Late spermatids [nTPM]":"41.7","Single Cell Type RNA - Leydig cells [nTPM]":"25.4","Single Cell Type RNA - Macrophages [nTPM]":"9.1","Single Cell Type RNA - Melanocytes [nTPM]":"55.2","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"7.5","Single Cell Type RNA - Muller glia cells [nTPM]":"102.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"41.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"30.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.6","Single Cell Type RNA - Paneth cells [nTPM]":"15.6","Single Cell Type RNA - Peritubular cells [nTPM]":"37.2","Single Cell Type RNA - Plasma cells [nTPM]":"2.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"27.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"302.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.6","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"25.8","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"5.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"59.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"222.3","Single Cell Type RNA - T-cells [nTPM]":"4.6","Single Cell Type RNA - Theca cells [nTPM]":"39.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"46.4","Single Cell Type RNA - Urothelial cells [nTPM]":"50.4"},{"Gene":"ALDOA","Gene synonym":[],"Ensembl":"ENSG00000149925","Gene description":"Aldolase, fructose-bisphosphate A","Uniprot":["P04075"],"Chromosome":"16","Position":"30064164-30070457","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Glycolysis"],"Molecular function":["Lyase"],"Disease involvement":["Cancer-related genes","Disease variant","Glycogen storage disease","Hereditary hemolytic anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"skeletal muscle":"26754.8","tongue":"9180.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"3267.9","Extravillous trophoblasts":"2322.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004177","CAB006252"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"640000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB006252":"AB_437007","HPA004177":"AB_1078128"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.79e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.32e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Tissue RNA - adipose tissue [nTPM]":"569.3","Tissue RNA - adrenal gland [nTPM]":"696.4","Tissue RNA - amygdala [nTPM]":"616.8","Tissue RNA - appendix [nTPM]":"443.1","Tissue RNA - basal ganglia [nTPM]":"697.4","Tissue RNA - bone marrow [nTPM]":"732.5","Tissue RNA - breast [nTPM]":"512.6","Tissue RNA - cerebellum [nTPM]":"617.3","Tissue RNA - cerebral cortex [nTPM]":"719.7","Tissue RNA - cervix [nTPM]":"566.0","Tissue RNA - choroid plexus [nTPM]":"617.0","Tissue RNA - colon [nTPM]":"774.1","Tissue RNA - duodenum [nTPM]":"517.9","Tissue RNA - endometrium 1 [nTPM]":"533.7","Tissue RNA - epididymis [nTPM]":"201.0","Tissue RNA - esophagus [nTPM]":"1302.0","Tissue RNA - fallopian tube [nTPM]":"449.7","Tissue RNA - gallbladder [nTPM]":"420.5","Tissue RNA - heart muscle [nTPM]":"2286.1","Tissue RNA - hippocampal formation [nTPM]":"731.9","Tissue RNA - hypothalamus [nTPM]":"652.0","Tissue RNA - kidney [nTPM]":"709.0","Tissue RNA - liver [nTPM]":"217.1","Tissue RNA - lung [nTPM]":"425.6","Tissue RNA - lymph node [nTPM]":"358.2","Tissue RNA - medulla oblongata [nTPM]":"762.3","Tissue RNA - midbrain [nTPM]":"654.0","Tissue RNA - ovary [nTPM]":"510.4","Tissue RNA - pancreas [nTPM]":"390.5","Tissue RNA - parathyroid gland [nTPM]":"943.1","Tissue RNA - pituitary gland [nTPM]":"525.1","Tissue RNA - placenta [nTPM]":"351.4","Tissue RNA - pons [nTPM]":"763.9","Tissue RNA - prostate [nTPM]":"457.7","Tissue RNA - rectum [nTPM]":"400.1","Tissue RNA - retina [nTPM]":"465.2","Tissue RNA - salivary gland [nTPM]":"904.9","Tissue RNA - seminal vesicle [nTPM]":"597.6","Tissue RNA - skeletal muscle [nTPM]":"26754.8","Tissue RNA - skin 1 [nTPM]":"643.4","Tissue RNA - small intestine [nTPM]":"488.3","Tissue RNA - smooth muscle [nTPM]":"465.2","Tissue RNA - spinal cord [nTPM]":"545.5","Tissue RNA - spleen [nTPM]":"417.5","Tissue RNA - stomach 1 [nTPM]":"595.0","Tissue RNA - testis [nTPM]":"138.7","Tissue RNA - thalamus [nTPM]":"657.8","Tissue RNA - thymus [nTPM]":"280.9","Tissue RNA - thyroid gland [nTPM]":"454.5","Tissue RNA - tongue [nTPM]":"9180.4","Tissue RNA - tonsil [nTPM]":"478.3","Tissue RNA - urinary bladder [nTPM]":"761.8","Tissue RNA - vagina [nTPM]":"740.3","Tissue RNA - white matter [nTPM]":"558.7","Cell RNA - A-431 [nTPM]":"2206.1","Cell RNA - A549 [nTPM]":"1620.4","Cell RNA - AF22 [nTPM]":"477.9","Cell RNA - AN3-CA [nTPM]":"1542.8","Cell RNA - ASC diff [nTPM]":"714.6","Cell RNA - ASC TERT1 [nTPM]":"808.5","Cell RNA - BEWO [nTPM]":"1520.8","Cell RNA - BJ [nTPM]":"1297.9","Cell RNA - BJ hTERT+ [nTPM]":"1336.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1291.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1603.0","Cell RNA - CACO-2 [nTPM]":"1158.1","Cell RNA - CAPAN-2 [nTPM]":"1643.6","Cell RNA - Daudi [nTPM]":"1487.6","Cell RNA - EFO-21 [nTPM]":"2072.2","Cell RNA - fHDF\/TERT166 [nTPM]":"1318.6","Cell RNA - GAMG [nTPM]":"708.6","Cell RNA - HaCaT [nTPM]":"1632.6","Cell RNA - HAP1 [nTPM]":"966.8","Cell RNA - HBEC3-KT [nTPM]":"2829.1","Cell RNA - HBF TERT88 [nTPM]":"939.3","Cell RNA - HDLM-2 [nTPM]":"658.5","Cell RNA - HEK 293 [nTPM]":"1272.9","Cell RNA - HEL [nTPM]":"1219.3","Cell RNA - HeLa [nTPM]":"1202.7","Cell RNA - Hep G2 [nTPM]":"2591.1","Cell RNA - HHSteC [nTPM]":"1112.5","Cell RNA - HL-60 [nTPM]":"1793.8","Cell RNA - HMC-1 [nTPM]":"1251.3","Cell RNA - HSkMC [nTPM]":"1115.7","Cell RNA - hTCEpi [nTPM]":"979.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1455.4","Cell RNA - hTERT-HME1 [nTPM]":"968.9","Cell RNA - hTERT-RPE1 [nTPM]":"2119.7","Cell RNA - HUVEC TERT2 [nTPM]":"965.4","Cell RNA - JURKAT [nTPM]":"686.9","Cell RNA - K-562 [nTPM]":"1070.0","Cell RNA - Karpas-707 [nTPM]":"951.1","Cell RNA - LHCN-M2 [nTPM]":"1393.4","Cell RNA - MCF7 [nTPM]":"3136.7","Cell RNA - MOLT-4 [nTPM]":"1100.2","Cell RNA - NB-4 [nTPM]":"1477.0","Cell RNA - NTERA-2 [nTPM]":"1192.8","Cell RNA - OE19 [nTPM]":"848.1","Cell RNA - PC-3 [nTPM]":"1346.6","Cell RNA - REH [nTPM]":"1613.9","Cell RNA - RH-30 [nTPM]":"765.2","Cell RNA - RPMI-8226 [nTPM]":"3353.2","Cell RNA - RPTEC TERT1 [nTPM]":"1629.4","Cell RNA - RT4 [nTPM]":"1230.5","Cell RNA - SCLC-21H [nTPM]":"950.7","Cell RNA - SH-SY5Y [nTPM]":"668.5","Cell RNA - SiHa [nTPM]":"808.6","Cell RNA - SK-BR-3 [nTPM]":"3368.5","Cell RNA - SK-MEL-30 [nTPM]":"1213.9","Cell RNA - SuSa [nTPM]":"591.2","Cell RNA - T-47d [nTPM]":"1433.0","Cell RNA - THP-1 [nTPM]":"1194.7","Cell RNA - TIME [nTPM]":"1162.5","Cell RNA - U-138 MG [nTPM]":"1892.3","Cell RNA - U-2 OS [nTPM]":"750.3","Cell RNA - U-2197 [nTPM]":"1046.7","Cell RNA - U-251 MG [nTPM]":"1430.0","Cell RNA - U-266\/70 [nTPM]":"1861.5","Cell RNA - U-266\/84 [nTPM]":"1387.3","Cell RNA - U-698 [nTPM]":"1369.3","Cell RNA - U-87 MG [nTPM]":"3524.5","Cell RNA - U-937 [nTPM]":"1715.9","Cell RNA - WM-115 [nTPM]":"1532.9","Blood RNA - basophil [nTPM]":"2050.6","Blood RNA - classical monocyte [nTPM]":"2694.7","Blood RNA - eosinophil [nTPM]":"2081.7","Blood RNA - gdT-cell [nTPM]":"1008.7","Blood RNA - intermediate monocyte [nTPM]":"2466.5","Blood RNA - MAIT T-cell [nTPM]":"1138.1","Blood RNA - memory B-cell [nTPM]":"908.5","Blood RNA - memory CD4 T-cell [nTPM]":"1091.7","Blood RNA - memory CD8 T-cell [nTPM]":"1047.0","Blood RNA - myeloid DC [nTPM]":"2182.7","Blood RNA - naive B-cell [nTPM]":"877.9","Blood RNA - naive CD4 T-cell [nTPM]":"1027.4","Blood RNA - naive CD8 T-cell [nTPM]":"996.9","Blood RNA - neutrophil [nTPM]":"2531.7","Blood RNA - NK-cell [nTPM]":"819.9","Blood RNA - non-classical monocyte [nTPM]":"2780.2","Blood RNA - plasmacytoid DC [nTPM]":"824.0","Blood RNA - T-reg [nTPM]":"1476.3","Blood RNA - total PBMC [nTPM]":"4372.2","Brain RNA - amygdala [nTPM]":"616.8","Brain RNA - basal ganglia [nTPM]":"697.4","Brain RNA - cerebellum [nTPM]":"617.3","Brain RNA - cerebral cortex [nTPM]":"719.7","Brain RNA - hippocampal formation [nTPM]":"731.9","Brain RNA - hypothalamus [nTPM]":"652.0","Brain RNA - medulla oblongata [nTPM]":"762.3","Brain RNA - midbrain [nTPM]":"654.0","Brain RNA - pons [nTPM]":"763.9","Brain RNA - spinal cord [nTPM]":"545.5","Brain RNA - thalamus [nTPM]":"657.8","Brain RNA - white matter [nTPM]":"558.7","Single Cell Type RNA - Adipocytes [nTPM]":"17.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"32.4","Single Cell Type RNA - Astrocytes [nTPM]":"83.2","Single Cell Type RNA - B-cells [nTPM]":"281.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"792.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"716.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3267.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"784.8","Single Cell Type RNA - Bipolar cells [nTPM]":"387.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"34.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1968.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"273.1","Single Cell Type RNA - Club cells [nTPM]":"1385.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"42.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"118.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1194.1","Single Cell Type RNA - dendritic cells [nTPM]":"107.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"1834.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"111.6","Single Cell Type RNA - Ductal cells [nTPM]":"120.9","Single Cell Type RNA - Early spermatids [nTPM]":"258.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.8","Single Cell Type RNA - Endothelial cells [nTPM]":"261.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"323.9","Single Cell Type RNA - Erythroid cells [nTPM]":"215.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"66.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"76.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2322.1","Single Cell Type RNA - Fibroblasts [nTPM]":"329.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"513.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.1","Single Cell Type RNA - granulocytes [nTPM]":"196.5","Single Cell Type RNA - Granulosa cells [nTPM]":"18.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"289.5","Single Cell Type RNA - Hepatocytes [nTPM]":"102.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1181.9","Single Cell Type RNA - Horizontal cells [nTPM]":"733.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"70.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"755.1","Single Cell Type RNA - Ionocytes [nTPM]":"1265.4","Single Cell Type RNA - Kupffer cells [nTPM]":"632.2","Single Cell Type RNA - Langerhans cells [nTPM]":"715.4","Single Cell Type RNA - Late spermatids [nTPM]":"1152.4","Single Cell Type RNA - Leydig cells [nTPM]":"380.8","Single Cell Type RNA - Macrophages [nTPM]":"388.8","Single Cell Type RNA - Melanocytes [nTPM]":"924.9","Single Cell Type RNA - Microglial cells [nTPM]":"50.6","Single Cell Type RNA - monocytes [nTPM]":"417.7","Single Cell Type RNA - Muller glia cells [nTPM]":"662.1","Single Cell Type RNA - NK-cells [nTPM]":"328.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"40.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"60.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"126.2","Single Cell Type RNA - Paneth cells [nTPM]":"1497.1","Single Cell Type RNA - Peritubular cells [nTPM]":"405.1","Single Cell Type RNA - Plasma cells [nTPM]":"409.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"676.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1755.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"75.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"700.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"298.9","Single Cell Type RNA - Sertoli cells [nTPM]":"486.4","Single Cell Type RNA - Skeletal myocytes [nTPM]":"680.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"572.9","Single Cell Type RNA - Spermatocytes [nTPM]":"25.8","Single Cell Type RNA - Spermatogonia [nTPM]":"123.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1174.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"684.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1361.3","Single Cell Type RNA - T-cells [nTPM]":"294.3","Single Cell Type RNA - Theca cells [nTPM]":"15.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"937.7","Single Cell Type RNA - Urothelial cells [nTPM]":"1146.2"},{"Gene":"ALDOB","Gene synonym":[],"Ensembl":"ENSG00000136872","Gene description":"Aldolase, fructose-bisphosphate B","Uniprot":["P05062"],"Chromosome":"9","Position":"101420560-101449664","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Glycolysis"],"Molecular function":["Lyase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"27","RNA tissue specific nTPM":{"intestine":"5736.6","kidney":"7181.0","liver":"11160.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Proximal enterocytes":"20078.3","Proximal tubular cells":"7956.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"31","RNA cancer specific FPKM":{"liver cancer":"1414.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"21.4","NB-4":"21.0","RPMI-8226":"28.6","SH-SY5Y":"20.6"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002198","CAB020827"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"560000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB020827":null,"HPA002198":"AB_1078129"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.3","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"17.0","Tissue RNA - basal ganglia [nTPM]":"0.7","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.7","Tissue RNA - cerebellum [nTPM]":"1.0","Tissue RNA - cerebral cortex [nTPM]":"2.3","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"30.1","Tissue RNA - duodenum [nTPM]":"4073.8","Tissue RNA - endometrium 1 [nTPM]":"2.8","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"0.7","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"176.9","Tissue RNA - heart muscle [nTPM]":"1.0","Tissue RNA - hippocampal formation [nTPM]":"2.4","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"7181.0","Tissue RNA - liver [nTPM]":"11160.8","Tissue RNA - lung [nTPM]":"0.5","Tissue RNA - lymph node [nTPM]":"4.9","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"292.7","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"5.6","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"2.1","Tissue RNA - rectum [nTPM]":"5.6","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"5736.6","Tissue RNA - smooth muscle [nTPM]":"7.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"2.0","Tissue RNA - stomach 1 [nTPM]":"34.3","Tissue RNA - testis [nTPM]":"1.1","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.7","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.8","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"21.4","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"4.5","Cell RNA - EFO-21 [nTPM]":"1.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.6","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"2.2","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"1.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"6.1","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"1.0","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"21.0","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.5","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"4.6","Cell RNA - RPMI-8226 [nTPM]":"28.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"4.3","Cell RNA - SH-SY5Y [nTPM]":"20.6","Cell RNA - SiHa [nTPM]":"2.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"1.9","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"1.0","Cell RNA - U-2197 [nTPM]":"7.1","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"0.7","Cell RNA - U-698 [nTPM]":"2.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"1.6","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.7","Brain RNA - cerebellum [nTPM]":"1.0","Brain RNA - cerebral cortex [nTPM]":"2.3","Brain RNA - hippocampal formation [nTPM]":"2.4","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"39.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"308.8","Single Cell Type RNA - Club cells [nTPM]":"0.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"150.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"620.3","Single Cell Type RNA - Ductal cells [nTPM]":"4.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"3.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"50.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"253.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"49.2","Single Cell Type RNA - Hepatocytes [nTPM]":"3225.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"464.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"66.2","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"38.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"3.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"182.1","Single Cell Type RNA - Paneth cells [nTPM]":"997.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20078.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7956.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"20.6","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"412.7","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"ALG1","Gene synonym":["CDG1K","HMAT1","HMT-1","Mat-1"],"Ensembl":"ENSG00000033011","Gene description":"ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase","Uniprot":["Q9BT22"],"Chromosome":"16","Position":"5033923-5087379","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060392"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Endoplasmic reticulum"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Nucleoli fibrillar center"],"Antibody RRID":{"HPA060392":"AB_2684273"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.79e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.93e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.3","Tissue RNA - adrenal gland [nTPM]":"19.6","Tissue RNA - amygdala [nTPM]":"6.2","Tissue RNA - appendix [nTPM]":"12.8","Tissue RNA - basal ganglia [nTPM]":"6.6","Tissue RNA - bone marrow [nTPM]":"7.7","Tissue RNA - breast [nTPM]":"9.9","Tissue RNA - cerebellum [nTPM]":"6.1","Tissue RNA - cerebral cortex [nTPM]":"7.9","Tissue RNA - cervix [nTPM]":"12.4","Tissue RNA - choroid plexus [nTPM]":"12.7","Tissue RNA - colon [nTPM]":"18.8","Tissue RNA - duodenum [nTPM]":"15.8","Tissue RNA - endometrium 1 [nTPM]":"11.0","Tissue RNA - epididymis [nTPM]":"14.5","Tissue RNA - esophagus [nTPM]":"11.2","Tissue RNA - fallopian tube [nTPM]":"12.4","Tissue RNA - gallbladder [nTPM]":"9.8","Tissue RNA - heart muscle [nTPM]":"8.3","Tissue RNA - hippocampal formation [nTPM]":"6.5","Tissue RNA - hypothalamus [nTPM]":"6.6","Tissue RNA - kidney [nTPM]":"12.6","Tissue RNA - liver [nTPM]":"21.0","Tissue RNA - lung [nTPM]":"9.3","Tissue RNA - lymph node [nTPM]":"12.4","Tissue RNA - medulla oblongata [nTPM]":"6.3","Tissue RNA - midbrain [nTPM]":"6.0","Tissue RNA - ovary [nTPM]":"8.8","Tissue RNA - pancreas [nTPM]":"26.8","Tissue RNA - parathyroid gland [nTPM]":"17.5","Tissue RNA - pituitary gland [nTPM]":"10.9","Tissue RNA - placenta [nTPM]":"9.5","Tissue RNA - pons [nTPM]":"6.9","Tissue RNA - prostate [nTPM]":"10.5","Tissue RNA - rectum [nTPM]":"16.3","Tissue RNA - retina [nTPM]":"6.8","Tissue RNA - salivary gland [nTPM]":"18.8","Tissue RNA - seminal vesicle [nTPM]":"10.6","Tissue RNA - skeletal muscle [nTPM]":"7.4","Tissue RNA - skin 1 [nTPM]":"8.8","Tissue RNA - small intestine [nTPM]":"13.1","Tissue RNA - smooth muscle [nTPM]":"12.0","Tissue RNA - spinal cord [nTPM]":"5.8","Tissue RNA - spleen [nTPM]":"15.0","Tissue RNA - stomach 1 [nTPM]":"19.6","Tissue RNA - testis [nTPM]":"20.8","Tissue RNA - thalamus [nTPM]":"6.5","Tissue RNA - thymus [nTPM]":"12.0","Tissue RNA - thyroid gland [nTPM]":"11.6","Tissue RNA - tongue [nTPM]":"5.5","Tissue RNA - tonsil [nTPM]":"12.1","Tissue RNA - urinary bladder [nTPM]":"12.4","Tissue RNA - vagina [nTPM]":"8.3","Tissue RNA - white matter [nTPM]":"6.8","Cell RNA - A-431 [nTPM]":"24.0","Cell RNA - A549 [nTPM]":"53.7","Cell RNA - AF22 [nTPM]":"10.8","Cell RNA - AN3-CA [nTPM]":"25.5","Cell RNA - ASC diff [nTPM]":"40.7","Cell RNA - ASC TERT1 [nTPM]":"24.2","Cell RNA - BEWO [nTPM]":"26.4","Cell RNA - BJ [nTPM]":"50.6","Cell RNA - BJ hTERT+ [nTPM]":"50.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"46.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"46.4","Cell RNA - CACO-2 [nTPM]":"44.8","Cell RNA - CAPAN-2 [nTPM]":"72.4","Cell RNA - Daudi [nTPM]":"44.4","Cell RNA - EFO-21 [nTPM]":"43.1","Cell RNA - fHDF\/TERT166 [nTPM]":"48.0","Cell RNA - GAMG [nTPM]":"20.7","Cell RNA - HaCaT [nTPM]":"58.2","Cell RNA - HAP1 [nTPM]":"30.1","Cell RNA - HBEC3-KT [nTPM]":"36.2","Cell RNA - HBF TERT88 [nTPM]":"31.6","Cell RNA - HDLM-2 [nTPM]":"42.0","Cell RNA - HEK 293 [nTPM]":"43.3","Cell RNA - HEL [nTPM]":"20.7","Cell RNA - HeLa [nTPM]":"40.1","Cell RNA - Hep G2 [nTPM]":"87.1","Cell RNA - HHSteC [nTPM]":"33.4","Cell RNA - HL-60 [nTPM]":"37.6","Cell RNA - HMC-1 [nTPM]":"37.3","Cell RNA - HSkMC [nTPM]":"29.7","Cell RNA - hTCEpi [nTPM]":"26.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"36.2","Cell RNA - hTERT-HME1 [nTPM]":"23.0","Cell RNA - hTERT-RPE1 [nTPM]":"18.5","Cell RNA - HUVEC TERT2 [nTPM]":"28.7","Cell RNA - JURKAT [nTPM]":"32.2","Cell RNA - K-562 [nTPM]":"29.5","Cell RNA - Karpas-707 [nTPM]":"44.7","Cell RNA - LHCN-M2 [nTPM]":"34.5","Cell RNA - MCF7 [nTPM]":"50.1","Cell RNA - MOLT-4 [nTPM]":"28.9","Cell RNA - NB-4 [nTPM]":"40.7","Cell RNA - NTERA-2 [nTPM]":"51.2","Cell RNA - OE19 [nTPM]":"31.7","Cell RNA - PC-3 [nTPM]":"33.6","Cell RNA - REH [nTPM]":"48.8","Cell RNA - RH-30 [nTPM]":"16.0","Cell RNA - RPMI-8226 [nTPM]":"124.9","Cell RNA - RPTEC TERT1 [nTPM]":"28.3","Cell RNA - RT4 [nTPM]":"18.7","Cell RNA - SCLC-21H [nTPM]":"20.7","Cell RNA - SH-SY5Y [nTPM]":"21.7","Cell RNA - SiHa [nTPM]":"49.3","Cell RNA - SK-BR-3 [nTPM]":"67.8","Cell RNA - SK-MEL-30 [nTPM]":"27.4","Cell RNA - SuSa [nTPM]":"14.3","Cell RNA - T-47d [nTPM]":"45.1","Cell RNA - THP-1 [nTPM]":"29.2","Cell RNA - TIME [nTPM]":"29.8","Cell RNA - U-138 MG [nTPM]":"22.5","Cell RNA - U-2 OS [nTPM]":"25.6","Cell RNA - U-2197 [nTPM]":"134.7","Cell RNA - U-251 MG [nTPM]":"40.1","Cell RNA - U-266\/70 [nTPM]":"39.8","Cell RNA - U-266\/84 [nTPM]":"59.3","Cell RNA - U-698 [nTPM]":"30.2","Cell RNA - U-87 MG [nTPM]":"20.5","Cell RNA - U-937 [nTPM]":"39.8","Cell RNA - WM-115 [nTPM]":"38.1","Blood RNA - basophil [nTPM]":"11.5","Blood RNA - classical monocyte [nTPM]":"79.9","Blood RNA - eosinophil [nTPM]":"28.8","Blood RNA - gdT-cell [nTPM]":"87.2","Blood RNA - intermediate monocyte [nTPM]":"80.6","Blood RNA - MAIT T-cell [nTPM]":"77.1","Blood RNA - memory B-cell [nTPM]":"72.9","Blood RNA - memory CD4 T-cell [nTPM]":"74.9","Blood RNA - memory CD8 T-cell [nTPM]":"86.3","Blood RNA - myeloid DC [nTPM]":"86.7","Blood RNA - naive B-cell [nTPM]":"73.9","Blood RNA - naive CD4 T-cell [nTPM]":"66.7","Blood RNA - naive CD8 T-cell [nTPM]":"75.0","Blood RNA - neutrophil [nTPM]":"4.3","Blood RNA - NK-cell [nTPM]":"79.8","Blood RNA - non-classical monocyte [nTPM]":"80.0","Blood RNA - plasmacytoid DC [nTPM]":"75.6","Blood RNA - T-reg [nTPM]":"81.1","Blood RNA - total PBMC [nTPM]":"126.6","Brain RNA - amygdala [nTPM]":"6.2","Brain RNA - basal ganglia [nTPM]":"6.6","Brain RNA - cerebellum [nTPM]":"6.1","Brain RNA - cerebral cortex [nTPM]":"7.9","Brain RNA - hippocampal formation [nTPM]":"6.5","Brain RNA - hypothalamus [nTPM]":"6.6","Brain RNA - medulla oblongata [nTPM]":"6.3","Brain RNA - midbrain [nTPM]":"6.0","Brain RNA - pons [nTPM]":"6.9","Brain RNA - spinal cord [nTPM]":"5.8","Brain RNA - thalamus [nTPM]":"6.5","Brain RNA - white matter [nTPM]":"6.8","Single Cell Type RNA - Adipocytes [nTPM]":"4.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.1","Single Cell Type RNA - Astrocytes [nTPM]":"4.2","Single Cell Type RNA - B-cells [nTPM]":"11.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"7.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"14.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.2","Single Cell Type RNA - dendritic cells [nTPM]":"7.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"19.5","Single Cell Type RNA - Early spermatids [nTPM]":"10.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.1","Single Cell Type RNA - Endothelial cells [nTPM]":"8.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.3","Single Cell Type RNA - Erythroid cells [nTPM]":"12.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"28.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.7","Single Cell Type RNA - Fibroblasts [nTPM]":"9.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"8.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.6","Single Cell Type RNA - Hepatocytes [nTPM]":"17.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"21.7","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.0","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"10.6","Single Cell Type RNA - Langerhans cells [nTPM]":"2.4","Single Cell Type RNA - Late spermatids [nTPM]":"25.5","Single Cell Type RNA - Leydig cells [nTPM]":"9.6","Single Cell Type RNA - Macrophages [nTPM]":"7.6","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"9.3","Single Cell Type RNA - Muller glia cells [nTPM]":"7.5","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.6","Single Cell Type RNA - Paneth cells [nTPM]":"11.1","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"22.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.1","Single Cell Type RNA - Spermatocytes [nTPM]":"28.0","Single Cell Type RNA - Spermatogonia [nTPM]":"16.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.5","Single Cell Type RNA - T-cells [nTPM]":"8.6","Single Cell Type RNA - Theca cells [nTPM]":"13.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.0","Single Cell Type RNA - Urothelial cells [nTPM]":"4.4"},{"Gene":"ALG11","Gene synonym":["CDG1P","KIAA0266"],"Ensembl":"ENSG00000253710","Gene description":"ALG11 alpha-1,2-mannosyltransferase","Uniprot":["Q2TAA5"],"Chromosome":"13","Position":"52012391-52079232","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047214"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047214":"AB_10961640"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.89e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-3"},"Tissue RNA - adipose tissue [nTPM]":"10.1","Tissue RNA - adrenal gland [nTPM]":"9.5","Tissue RNA - amygdala [nTPM]":"7.4","Tissue RNA - appendix [nTPM]":"8.3","Tissue RNA - basal ganglia [nTPM]":"8.4","Tissue RNA - bone marrow [nTPM]":"4.1","Tissue RNA - breast [nTPM]":"12.1","Tissue RNA - cerebellum [nTPM]":"9.5","Tissue RNA - cerebral cortex [nTPM]":"9.7","Tissue RNA - cervix [nTPM]":"12.1","Tissue RNA - choroid plexus [nTPM]":"1.9","Tissue RNA - colon [nTPM]":"11.0","Tissue RNA - duodenum [nTPM]":"10.1","Tissue RNA - endometrium 1 [nTPM]":"11.0","Tissue RNA - epididymis [nTPM]":"9.4","Tissue RNA - esophagus [nTPM]":"7.5","Tissue RNA - fallopian tube [nTPM]":"10.8","Tissue RNA - gallbladder [nTPM]":"8.9","Tissue RNA - heart muscle [nTPM]":"10.4","Tissue RNA - hippocampal formation [nTPM]":"7.5","Tissue RNA - hypothalamus [nTPM]":"4.8","Tissue RNA - kidney [nTPM]":"14.6","Tissue RNA - liver [nTPM]":"19.2","Tissue RNA - lung [nTPM]":"9.1","Tissue RNA - lymph node [nTPM]":"8.1","Tissue RNA - medulla oblongata [nTPM]":"4.8","Tissue RNA - midbrain [nTPM]":"4.0","Tissue RNA - ovary [nTPM]":"11.6","Tissue RNA - pancreas [nTPM]":"8.6","Tissue RNA - parathyroid gland [nTPM]":"17.2","Tissue RNA - pituitary gland [nTPM]":"2.4","Tissue RNA - placenta [nTPM]":"12.7","Tissue RNA - pons [nTPM]":"4.6","Tissue RNA - prostate [nTPM]":"12.1","Tissue RNA - rectum [nTPM]":"11.8","Tissue RNA - retina [nTPM]":"9.0","Tissue RNA - salivary gland [nTPM]":"10.9","Tissue RNA - seminal vesicle [nTPM]":"10.9","Tissue RNA - skeletal muscle [nTPM]":"6.5","Tissue RNA - skin 1 [nTPM]":"7.2","Tissue RNA - small intestine [nTPM]":"9.7","Tissue RNA - smooth muscle [nTPM]":"11.4","Tissue RNA - spinal cord [nTPM]":"2.9","Tissue RNA - spleen [nTPM]":"10.1","Tissue RNA - stomach 1 [nTPM]":"11.6","Tissue RNA - testis [nTPM]":"6.2","Tissue RNA - thalamus [nTPM]":"4.7","Tissue RNA - thymus [nTPM]":"9.5","Tissue RNA - thyroid gland [nTPM]":"16.8","Tissue RNA - tongue [nTPM]":"8.8","Tissue RNA - tonsil [nTPM]":"8.6","Tissue RNA - urinary bladder [nTPM]":"8.7","Tissue RNA - vagina [nTPM]":"2.5","Tissue RNA - white matter [nTPM]":"9.6","Cell RNA - A-431 [nTPM]":"6.7","Cell RNA - A549 [nTPM]":"10.5","Cell RNA - AF22 [nTPM]":"17.8","Cell RNA - AN3-CA [nTPM]":"15.2","Cell RNA - ASC diff [nTPM]":"18.6","Cell RNA - ASC TERT1 [nTPM]":"13.3","Cell RNA - BEWO [nTPM]":"14.2","Cell RNA - BJ [nTPM]":"17.7","Cell RNA - BJ hTERT+ [nTPM]":"16.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.3","Cell RNA - CACO-2 [nTPM]":"8.5","Cell RNA - CAPAN-2 [nTPM]":"14.5","Cell RNA - Daudi [nTPM]":"16.2","Cell RNA - EFO-21 [nTPM]":"4.2","Cell RNA - fHDF\/TERT166 [nTPM]":"18.4","Cell RNA - GAMG [nTPM]":"15.8","Cell RNA - HaCaT [nTPM]":"15.3","Cell RNA - HAP1 [nTPM]":"18.2","Cell RNA - HBEC3-KT [nTPM]":"12.0","Cell RNA - HBF TERT88 [nTPM]":"17.0","Cell RNA - HDLM-2 [nTPM]":"16.7","Cell RNA - HEK 293 [nTPM]":"12.9","Cell RNA - HEL [nTPM]":"31.0","Cell RNA - HeLa [nTPM]":"8.8","Cell RNA - Hep G2 [nTPM]":"11.4","Cell RNA - HHSteC [nTPM]":"14.1","Cell RNA - HL-60 [nTPM]":"28.3","Cell RNA - HMC-1 [nTPM]":"31.0","Cell RNA - HSkMC [nTPM]":"12.9","Cell RNA - hTCEpi [nTPM]":"17.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.1","Cell RNA - hTERT-HME1 [nTPM]":"18.4","Cell RNA - hTERT-RPE1 [nTPM]":"14.1","Cell RNA - HUVEC TERT2 [nTPM]":"11.5","Cell RNA - JURKAT [nTPM]":"18.5","Cell RNA - K-562 [nTPM]":"17.8","Cell RNA - Karpas-707 [nTPM]":"10.4","Cell RNA - LHCN-M2 [nTPM]":"19.4","Cell RNA - MCF7 [nTPM]":"5.7","Cell RNA - MOLT-4 [nTPM]":"14.7","Cell RNA - NB-4 [nTPM]":"9.7","Cell RNA - NTERA-2 [nTPM]":"19.2","Cell RNA - OE19 [nTPM]":"28.8","Cell RNA - PC-3 [nTPM]":"7.5","Cell RNA - REH [nTPM]":"15.2","Cell RNA - RH-30 [nTPM]":"11.9","Cell RNA - RPMI-8226 [nTPM]":"8.9","Cell RNA - RPTEC TERT1 [nTPM]":"16.7","Cell RNA - RT4 [nTPM]":"10.8","Cell RNA - SCLC-21H [nTPM]":"6.9","Cell RNA - SH-SY5Y [nTPM]":"15.2","Cell RNA - SiHa [nTPM]":"11.9","Cell RNA - SK-BR-3 [nTPM]":"17.1","Cell RNA - SK-MEL-30 [nTPM]":"11.9","Cell RNA - SuSa [nTPM]":"15.0","Cell RNA - T-47d [nTPM]":"11.9","Cell RNA - THP-1 [nTPM]":"20.8","Cell RNA - TIME [nTPM]":"17.8","Cell RNA - U-138 MG [nTPM]":"10.4","Cell RNA - U-2 OS [nTPM]":"11.5","Cell RNA - U-2197 [nTPM]":"13.6","Cell RNA - U-251 MG [nTPM]":"11.8","Cell RNA - U-266\/70 [nTPM]":"9.1","Cell RNA - U-266\/84 [nTPM]":"13.5","Cell RNA - U-698 [nTPM]":"17.7","Cell RNA - U-87 MG [nTPM]":"6.4","Cell RNA - U-937 [nTPM]":"11.7","Cell RNA - WM-115 [nTPM]":"18.0","Blood RNA - basophil [nTPM]":"13.2","Blood RNA - classical monocyte [nTPM]":"5.4","Blood RNA - eosinophil [nTPM]":"7.2","Blood RNA - gdT-cell [nTPM]":"7.7","Blood RNA - intermediate monocyte [nTPM]":"4.5","Blood RNA - MAIT T-cell [nTPM]":"7.6","Blood RNA - memory B-cell [nTPM]":"5.1","Blood RNA - memory CD4 T-cell [nTPM]":"7.0","Blood RNA - memory CD8 T-cell [nTPM]":"6.6","Blood RNA - myeloid DC [nTPM]":"6.9","Blood RNA - naive B-cell [nTPM]":"7.1","Blood RNA - naive CD4 T-cell [nTPM]":"8.9","Blood RNA - naive CD8 T-cell [nTPM]":"8.9","Blood RNA - neutrophil [nTPM]":"2.2","Blood RNA - NK-cell [nTPM]":"7.3","Blood RNA - non-classical monocyte [nTPM]":"12.0","Blood RNA - plasmacytoid DC [nTPM]":"9.8","Blood RNA - T-reg [nTPM]":"7.2","Blood RNA - total PBMC [nTPM]":"4.9","Brain RNA - amygdala [nTPM]":"7.4","Brain RNA - basal ganglia [nTPM]":"8.4","Brain RNA - cerebellum [nTPM]":"9.5","Brain RNA - cerebral cortex [nTPM]":"9.7","Brain RNA - hippocampal formation [nTPM]":"7.5","Brain RNA - hypothalamus [nTPM]":"4.8","Brain RNA - medulla oblongata [nTPM]":"4.8","Brain RNA - midbrain [nTPM]":"4.0","Brain RNA - pons [nTPM]":"4.6","Brain RNA - spinal cord [nTPM]":"2.9","Brain RNA - thalamus [nTPM]":"4.7","Brain RNA - white matter [nTPM]":"9.6","Single Cell Type RNA - Adipocytes [nTPM]":"5.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.2","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"7.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"6.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"9.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - dendritic cells [nTPM]":"6.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.3","Single Cell Type RNA - Endothelial cells [nTPM]":"5.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"12.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.9","Single Cell Type RNA - Fibroblasts [nTPM]":"8.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.4","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"6.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"4.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.5","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.7","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"2.2","Single Cell Type RNA - Langerhans cells [nTPM]":"3.1","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"3.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"2.6","Single Cell Type RNA - Muller glia cells [nTPM]":"2.8","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.7","Single Cell Type RNA - Paneth cells [nTPM]":"1.7","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"14.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.4","Single Cell Type RNA - Spermatocytes [nTPM]":"4.8","Single Cell Type RNA - Spermatogonia [nTPM]":"3.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.8","Single Cell Type RNA - T-cells [nTPM]":"7.2","Single Cell Type RNA - Theca cells [nTPM]":"3.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.1","Single Cell Type RNA - Urothelial cells [nTPM]":"4.0"},{"Gene":"ALG12","Gene synonym":["CDG1G","ECM39"],"Ensembl":"ENSG00000182858","Gene description":"ALG12 alpha-1,6-mannosyltransferase","Uniprot":["Q9BV10"],"Chromosome":"22","Position":"49900229-49918438","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003076","HPA051665"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA003076":"AB_2666777","HPA051665":"AB_2681566"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.09e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.60e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.3","Tissue RNA - adrenal gland [nTPM]":"8.0","Tissue RNA - amygdala [nTPM]":"3.5","Tissue RNA - appendix [nTPM]":"7.3","Tissue RNA - basal ganglia [nTPM]":"4.5","Tissue RNA - bone marrow [nTPM]":"5.9","Tissue RNA - breast [nTPM]":"6.4","Tissue RNA - cerebellum [nTPM]":"6.2","Tissue RNA - cerebral cortex [nTPM]":"4.7","Tissue RNA - cervix [nTPM]":"7.6","Tissue RNA - choroid plexus [nTPM]":"4.9","Tissue RNA - colon [nTPM]":"8.8","Tissue RNA - duodenum [nTPM]":"11.1","Tissue RNA - endometrium 1 [nTPM]":"8.3","Tissue RNA - epididymis [nTPM]":"6.5","Tissue RNA - esophagus [nTPM]":"8.0","Tissue RNA - fallopian tube [nTPM]":"7.6","Tissue RNA - gallbladder [nTPM]":"6.6","Tissue RNA - heart muscle [nTPM]":"8.3","Tissue RNA - hippocampal formation [nTPM]":"3.9","Tissue RNA - hypothalamus [nTPM]":"2.6","Tissue RNA - kidney [nTPM]":"10.3","Tissue RNA - liver [nTPM]":"14.5","Tissue RNA - lung [nTPM]":"7.0","Tissue RNA - lymph node [nTPM]":"5.6","Tissue RNA - medulla oblongata [nTPM]":"4.5","Tissue RNA - midbrain [nTPM]":"4.3","Tissue RNA - ovary [nTPM]":"7.1","Tissue RNA - pancreas [nTPM]":"11.4","Tissue RNA - parathyroid gland [nTPM]":"11.8","Tissue RNA - pituitary gland [nTPM]":"6.6","Tissue RNA - placenta [nTPM]":"5.4","Tissue RNA - pons [nTPM]":"4.7","Tissue RNA - prostate [nTPM]":"9.1","Tissue RNA - rectum [nTPM]":"4.1","Tissue RNA - retina [nTPM]":"3.0","Tissue RNA - salivary gland [nTPM]":"12.0","Tissue RNA - seminal vesicle [nTPM]":"5.6","Tissue RNA - skeletal muscle [nTPM]":"6.1","Tissue RNA - skin 1 [nTPM]":"7.2","Tissue RNA - small intestine [nTPM]":"8.9","Tissue RNA - smooth muscle [nTPM]":"4.4","Tissue RNA - spinal cord [nTPM]":"3.3","Tissue RNA - spleen [nTPM]":"7.2","Tissue RNA - stomach 1 [nTPM]":"10.3","Tissue RNA - testis [nTPM]":"4.5","Tissue RNA - thalamus [nTPM]":"4.9","Tissue RNA - thymus [nTPM]":"6.5","Tissue RNA - thyroid gland [nTPM]":"11.7","Tissue RNA - tongue [nTPM]":"4.5","Tissue RNA - tonsil [nTPM]":"4.8","Tissue RNA - urinary bladder [nTPM]":"7.7","Tissue RNA - vagina [nTPM]":"6.8","Tissue RNA - white matter [nTPM]":"8.4","Cell RNA - A-431 [nTPM]":"8.6","Cell RNA - A549 [nTPM]":"8.5","Cell RNA - AF22 [nTPM]":"8.8","Cell RNA - AN3-CA [nTPM]":"14.7","Cell RNA - ASC diff [nTPM]":"16.4","Cell RNA - ASC TERT1 [nTPM]":"7.6","Cell RNA - BEWO [nTPM]":"9.8","Cell RNA - BJ [nTPM]":"8.8","Cell RNA - BJ hTERT+ [nTPM]":"7.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.2","Cell RNA - CACO-2 [nTPM]":"14.0","Cell RNA - CAPAN-2 [nTPM]":"12.0","Cell RNA - Daudi [nTPM]":"4.6","Cell RNA - EFO-21 [nTPM]":"7.8","Cell RNA - fHDF\/TERT166 [nTPM]":"7.8","Cell RNA - GAMG [nTPM]":"11.1","Cell RNA - HaCaT [nTPM]":"15.2","Cell RNA - HAP1 [nTPM]":"10.7","Cell RNA - HBEC3-KT [nTPM]":"10.4","Cell RNA - HBF TERT88 [nTPM]":"5.0","Cell RNA - HDLM-2 [nTPM]":"7.3","Cell RNA - HEK 293 [nTPM]":"15.9","Cell RNA - HEL [nTPM]":"4.2","Cell RNA - HeLa [nTPM]":"14.7","Cell RNA - Hep G2 [nTPM]":"14.1","Cell RNA - HHSteC [nTPM]":"18.6","Cell RNA - HL-60 [nTPM]":"10.6","Cell RNA - HMC-1 [nTPM]":"8.9","Cell RNA - HSkMC [nTPM]":"11.6","Cell RNA - hTCEpi [nTPM]":"10.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.9","Cell RNA - hTERT-HME1 [nTPM]":"14.3","Cell RNA - hTERT-RPE1 [nTPM]":"11.2","Cell RNA - HUVEC TERT2 [nTPM]":"9.9","Cell RNA - JURKAT [nTPM]":"10.3","Cell RNA - K-562 [nTPM]":"5.3","Cell RNA - Karpas-707 [nTPM]":"11.2","Cell RNA - LHCN-M2 [nTPM]":"5.4","Cell RNA - MCF7 [nTPM]":"19.6","Cell RNA - MOLT-4 [nTPM]":"10.4","Cell RNA - NB-4 [nTPM]":"8.6","Cell RNA - NTERA-2 [nTPM]":"8.4","Cell RNA - OE19 [nTPM]":"11.3","Cell RNA - PC-3 [nTPM]":"7.7","Cell RNA - REH [nTPM]":"17.2","Cell RNA - RH-30 [nTPM]":"11.0","Cell RNA - RPMI-8226 [nTPM]":"12.1","Cell RNA - RPTEC TERT1 [nTPM]":"10.6","Cell RNA - RT4 [nTPM]":"9.6","Cell RNA - SCLC-21H [nTPM]":"5.9","Cell RNA - SH-SY5Y [nTPM]":"9.6","Cell RNA - SiHa [nTPM]":"14.0","Cell RNA - SK-BR-3 [nTPM]":"26.3","Cell RNA - SK-MEL-30 [nTPM]":"11.4","Cell RNA - SuSa [nTPM]":"11.7","Cell RNA - T-47d [nTPM]":"10.8","Cell RNA - THP-1 [nTPM]":"9.4","Cell RNA - TIME [nTPM]":"7.7","Cell RNA - U-138 MG [nTPM]":"11.2","Cell RNA - U-2 OS [nTPM]":"8.5","Cell RNA - U-2197 [nTPM]":"7.9","Cell RNA - U-251 MG [nTPM]":"6.8","Cell RNA - U-266\/70 [nTPM]":"9.8","Cell RNA - U-266\/84 [nTPM]":"4.9","Cell RNA - U-698 [nTPM]":"6.1","Cell RNA - U-87 MG [nTPM]":"12.5","Cell RNA - U-937 [nTPM]":"8.0","Cell RNA - WM-115 [nTPM]":"10.9","Blood RNA - basophil [nTPM]":"21.4","Blood RNA - classical monocyte [nTPM]":"8.7","Blood RNA - eosinophil [nTPM]":"7.7","Blood RNA - gdT-cell [nTPM]":"11.5","Blood RNA - intermediate monocyte [nTPM]":"8.5","Blood RNA - MAIT T-cell [nTPM]":"11.7","Blood RNA - memory B-cell [nTPM]":"4.8","Blood RNA - memory CD4 T-cell [nTPM]":"8.9","Blood RNA - memory CD8 T-cell [nTPM]":"11.4","Blood RNA - myeloid DC [nTPM]":"7.6","Blood RNA - naive B-cell [nTPM]":"6.4","Blood RNA - naive CD4 T-cell [nTPM]":"7.3","Blood RNA - naive CD8 T-cell [nTPM]":"8.6","Blood RNA - neutrophil [nTPM]":"7.1","Blood RNA - NK-cell [nTPM]":"16.9","Blood RNA - non-classical monocyte [nTPM]":"10.1","Blood RNA - plasmacytoid DC [nTPM]":"7.7","Blood RNA - T-reg [nTPM]":"12.8","Blood RNA - total PBMC [nTPM]":"8.1","Brain RNA - amygdala [nTPM]":"3.5","Brain RNA - basal ganglia [nTPM]":"4.5","Brain RNA - cerebellum [nTPM]":"6.2","Brain RNA - cerebral cortex [nTPM]":"4.7","Brain RNA - hippocampal formation [nTPM]":"3.9","Brain RNA - hypothalamus [nTPM]":"2.6","Brain RNA - medulla oblongata [nTPM]":"4.5","Brain RNA - midbrain [nTPM]":"4.3","Brain RNA - pons [nTPM]":"4.7","Brain RNA - spinal cord [nTPM]":"3.3","Brain RNA - thalamus [nTPM]":"4.9","Brain RNA - white matter [nTPM]":"8.4","Single Cell Type RNA - Adipocytes [nTPM]":"6.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.1","Single Cell Type RNA - Astrocytes [nTPM]":"21.5","Single Cell Type RNA - B-cells [nTPM]":"10.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"5.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"10.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.5","Single Cell Type RNA - dendritic cells [nTPM]":"8.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"15.9","Single Cell Type RNA - Early spermatids [nTPM]":"6.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.0","Single Cell Type RNA - Endothelial cells [nTPM]":"8.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"22.4","Single Cell Type RNA - Fibroblasts [nTPM]":"10.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.2","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"7.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"15.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.6","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"30.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.9","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"9.2","Single Cell Type RNA - Langerhans cells [nTPM]":"5.3","Single Cell Type RNA - Late spermatids [nTPM]":"4.3","Single Cell Type RNA - Leydig cells [nTPM]":"8.7","Single Cell Type RNA - Macrophages [nTPM]":"8.7","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"9.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.9","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"40.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.3","Single Cell Type RNA - Paneth cells [nTPM]":"9.7","Single Cell Type RNA - Peritubular cells [nTPM]":"8.2","Single Cell Type RNA - Plasma cells [nTPM]":"15.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.7","Single Cell Type RNA - Spermatocytes [nTPM]":"12.9","Single Cell Type RNA - Spermatogonia [nTPM]":"9.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"26.3","Single Cell Type RNA - T-cells [nTPM]":"11.9","Single Cell Type RNA - Theca cells [nTPM]":"8.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.3","Single Cell Type RNA - Urothelial cells [nTPM]":"9.1"},{"Gene":"ALG13","Gene synonym":["CDG1S","CXorf45","FLJ23018","GLT28D1","MDS031","TDRD13","YGL047W"],"Ensembl":"ENSG00000101901","Gene description":"ALG13 UDP-N-acetylglucosaminyltransferase subunit","Uniprot":["Q9NP73"],"Chromosome":"X","Position":"111665811-111760649","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Glycosyltransferase","Hydrolase","Multifunctional enzyme","Protease","Thiol protease","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002853","HPA005498"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"11000000","Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA002853":"AB_1078131","HPA005498":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.10e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.1","Tissue RNA - adrenal gland [nTPM]":"17.9","Tissue RNA - amygdala [nTPM]":"10.5","Tissue RNA - appendix [nTPM]":"18.8","Tissue RNA - basal ganglia [nTPM]":"11.7","Tissue RNA - bone marrow [nTPM]":"16.6","Tissue RNA - breast [nTPM]":"18.3","Tissue RNA - cerebellum [nTPM]":"11.5","Tissue RNA - cerebral cortex [nTPM]":"19.0","Tissue RNA - cervix [nTPM]":"17.2","Tissue RNA - choroid plexus [nTPM]":"12.3","Tissue RNA - colon [nTPM]":"18.2","Tissue RNA - duodenum [nTPM]":"13.7","Tissue RNA - endometrium 1 [nTPM]":"16.1","Tissue RNA - epididymis [nTPM]":"20.5","Tissue RNA - esophagus [nTPM]":"14.7","Tissue RNA - fallopian tube [nTPM]":"15.4","Tissue RNA - gallbladder [nTPM]":"16.4","Tissue RNA - heart muscle [nTPM]":"13.2","Tissue RNA - hippocampal formation [nTPM]":"10.2","Tissue RNA - hypothalamus [nTPM]":"13.8","Tissue RNA - kidney [nTPM]":"21.0","Tissue RNA - liver [nTPM]":"23.8","Tissue RNA - lung [nTPM]":"13.8","Tissue RNA - lymph node [nTPM]":"23.4","Tissue RNA - medulla oblongata [nTPM]":"12.6","Tissue RNA - midbrain [nTPM]":"12.1","Tissue RNA - ovary [nTPM]":"15.8","Tissue RNA - pancreas [nTPM]":"14.7","Tissue RNA - parathyroid gland [nTPM]":"23.4","Tissue RNA - pituitary gland [nTPM]":"17.9","Tissue RNA - placenta [nTPM]":"14.1","Tissue RNA - pons [nTPM]":"13.3","Tissue RNA - prostate [nTPM]":"17.7","Tissue RNA - rectum [nTPM]":"19.4","Tissue RNA - retina [nTPM]":"11.8","Tissue RNA - salivary gland [nTPM]":"15.6","Tissue RNA - seminal vesicle [nTPM]":"13.4","Tissue RNA - skeletal muscle [nTPM]":"9.2","Tissue RNA - skin 1 [nTPM]":"19.4","Tissue RNA - small intestine [nTPM]":"17.3","Tissue RNA - smooth muscle [nTPM]":"17.5","Tissue RNA - spinal cord [nTPM]":"11.4","Tissue RNA - spleen [nTPM]":"18.5","Tissue RNA - stomach 1 [nTPM]":"15.5","Tissue RNA - testis [nTPM]":"17.4","Tissue RNA - thalamus [nTPM]":"11.8","Tissue RNA - thymus [nTPM]":"17.3","Tissue RNA - thyroid gland [nTPM]":"18.2","Tissue RNA - tongue [nTPM]":"9.9","Tissue RNA - tonsil [nTPM]":"20.1","Tissue RNA - urinary bladder [nTPM]":"21.3","Tissue RNA - vagina [nTPM]":"14.7","Tissue RNA - white matter [nTPM]":"16.6","Cell RNA - A-431 [nTPM]":"22.3","Cell RNA - A549 [nTPM]":"24.4","Cell RNA - AF22 [nTPM]":"21.8","Cell RNA - AN3-CA [nTPM]":"13.8","Cell RNA - ASC diff [nTPM]":"13.8","Cell RNA - ASC TERT1 [nTPM]":"19.6","Cell RNA - BEWO [nTPM]":"12.3","Cell RNA - BJ [nTPM]":"17.7","Cell RNA - BJ hTERT+ [nTPM]":"18.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"22.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"27.5","Cell RNA - CACO-2 [nTPM]":"24.9","Cell RNA - CAPAN-2 [nTPM]":"23.1","Cell RNA - Daudi [nTPM]":"19.5","Cell RNA - EFO-21 [nTPM]":"33.0","Cell RNA - fHDF\/TERT166 [nTPM]":"24.7","Cell RNA - GAMG [nTPM]":"46.5","Cell RNA - HaCaT [nTPM]":"12.6","Cell RNA - HAP1 [nTPM]":"26.1","Cell RNA - HBEC3-KT [nTPM]":"12.5","Cell RNA - HBF TERT88 [nTPM]":"23.5","Cell RNA - HDLM-2 [nTPM]":"14.4","Cell RNA - HEK 293 [nTPM]":"17.6","Cell RNA - HEL [nTPM]":"10.7","Cell RNA - HeLa [nTPM]":"26.1","Cell RNA - Hep G2 [nTPM]":"28.4","Cell RNA - HHSteC [nTPM]":"20.3","Cell RNA - HL-60 [nTPM]":"19.5","Cell RNA - HMC-1 [nTPM]":"40.5","Cell RNA - HSkMC [nTPM]":"23.6","Cell RNA - hTCEpi [nTPM]":"22.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.0","Cell RNA - hTERT-HME1 [nTPM]":"38.6","Cell RNA - hTERT-RPE1 [nTPM]":"23.3","Cell RNA - HUVEC TERT2 [nTPM]":"24.8","Cell RNA - JURKAT [nTPM]":"21.8","Cell RNA - K-562 [nTPM]":"23.9","Cell RNA - Karpas-707 [nTPM]":"53.5","Cell RNA - LHCN-M2 [nTPM]":"22.5","Cell RNA - MCF7 [nTPM]":"55.8","Cell RNA - MOLT-4 [nTPM]":"16.4","Cell RNA - NB-4 [nTPM]":"17.6","Cell RNA - NTERA-2 [nTPM]":"19.9","Cell RNA - OE19 [nTPM]":"66.3","Cell RNA - PC-3 [nTPM]":"33.6","Cell RNA - REH [nTPM]":"12.8","Cell RNA - RH-30 [nTPM]":"13.9","Cell RNA - RPMI-8226 [nTPM]":"26.7","Cell RNA - RPTEC TERT1 [nTPM]":"36.6","Cell RNA - RT4 [nTPM]":"34.0","Cell RNA - SCLC-21H [nTPM]":"13.1","Cell RNA - SH-SY5Y [nTPM]":"19.1","Cell RNA - SiHa [nTPM]":"25.2","Cell RNA - SK-BR-3 [nTPM]":"15.2","Cell RNA - SK-MEL-30 [nTPM]":"16.3","Cell RNA - SuSa [nTPM]":"21.7","Cell RNA - T-47d [nTPM]":"13.6","Cell RNA - THP-1 [nTPM]":"18.5","Cell RNA - TIME [nTPM]":"16.7","Cell RNA - U-138 MG [nTPM]":"19.2","Cell RNA - U-2 OS [nTPM]":"9.7","Cell RNA - U-2197 [nTPM]":"24.9","Cell RNA - U-251 MG [nTPM]":"34.4","Cell RNA - U-266\/70 [nTPM]":"25.8","Cell RNA - U-266\/84 [nTPM]":"47.1","Cell RNA - U-698 [nTPM]":"31.5","Cell RNA - U-87 MG [nTPM]":"20.5","Cell RNA - U-937 [nTPM]":"25.5","Cell RNA - WM-115 [nTPM]":"15.2","Blood RNA - basophil [nTPM]":"39.5","Blood RNA - classical monocyte [nTPM]":"15.8","Blood RNA - eosinophil [nTPM]":"16.6","Blood RNA - gdT-cell [nTPM]":"9.5","Blood RNA - intermediate monocyte [nTPM]":"16.3","Blood RNA - MAIT T-cell [nTPM]":"9.3","Blood RNA - memory B-cell [nTPM]":"10.6","Blood RNA - memory CD4 T-cell [nTPM]":"10.6","Blood RNA - memory CD8 T-cell [nTPM]":"9.2","Blood RNA - myeloid DC [nTPM]":"18.5","Blood RNA - naive B-cell [nTPM]":"12.1","Blood RNA - naive CD4 T-cell [nTPM]":"13.0","Blood RNA - naive CD8 T-cell [nTPM]":"10.8","Blood RNA - neutrophil [nTPM]":"3.0","Blood RNA - NK-cell [nTPM]":"4.6","Blood RNA - non-classical monocyte [nTPM]":"12.9","Blood RNA - plasmacytoid DC [nTPM]":"9.5","Blood RNA - T-reg [nTPM]":"14.6","Blood RNA - total PBMC [nTPM]":"9.6","Brain RNA - amygdala [nTPM]":"10.5","Brain RNA - basal ganglia [nTPM]":"11.7","Brain RNA - cerebellum [nTPM]":"11.5","Brain RNA - cerebral cortex [nTPM]":"19.0","Brain RNA - hippocampal formation [nTPM]":"10.2","Brain RNA - hypothalamus [nTPM]":"13.8","Brain RNA - medulla oblongata [nTPM]":"12.6","Brain RNA - midbrain [nTPM]":"12.1","Brain RNA - pons [nTPM]":"13.3","Brain RNA - spinal cord [nTPM]":"11.4","Brain RNA - thalamus [nTPM]":"11.8","Brain RNA - white matter [nTPM]":"16.6","Single Cell Type RNA - Adipocytes [nTPM]":"50.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"30.8","Single Cell Type RNA - Astrocytes [nTPM]":"33.6","Single Cell Type RNA - B-cells [nTPM]":"127.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"35.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"65.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"53.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"33.6","Single Cell Type RNA - Bipolar cells [nTPM]":"15.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"33.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"31.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"36.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.3","Single Cell Type RNA - dendritic cells [nTPM]":"73.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"39.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"45.0","Single Cell Type RNA - Ductal cells [nTPM]":"37.4","Single Cell Type RNA - Early spermatids [nTPM]":"21.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"48.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"31.1","Single Cell Type RNA - Endothelial cells [nTPM]":"37.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"26.5","Single Cell Type RNA - Erythroid cells [nTPM]":"27.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"64.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"52.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"39.1","Single Cell Type RNA - Fibroblasts [nTPM]":"34.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"37.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"47.9","Single Cell Type RNA - granulocytes [nTPM]":"109.8","Single Cell Type RNA - Granulosa cells [nTPM]":"15.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.2","Single Cell Type RNA - Hepatocytes [nTPM]":"28.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"42.5","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"57.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"49.0","Single Cell Type RNA - Ionocytes [nTPM]":"46.8","Single Cell Type RNA - Kupffer cells [nTPM]":"39.2","Single Cell Type RNA - Langerhans cells [nTPM]":"52.3","Single Cell Type RNA - Late spermatids [nTPM]":"9.4","Single Cell Type RNA - Leydig cells [nTPM]":"21.5","Single Cell Type RNA - Macrophages [nTPM]":"56.1","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"83.4","Single Cell Type RNA - monocytes [nTPM]":"41.8","Single Cell Type RNA - Muller glia cells [nTPM]":"16.0","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"41.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"77.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"58.0","Single Cell Type RNA - Paneth cells [nTPM]":"55.6","Single Cell Type RNA - Peritubular cells [nTPM]":"16.1","Single Cell Type RNA - Plasma cells [nTPM]":"60.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"46.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"38.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"55.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"35.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.5","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"38.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"46.2","Single Cell Type RNA - Spermatocytes [nTPM]":"32.6","Single Cell Type RNA - Spermatogonia [nTPM]":"22.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"35.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"48.7","Single Cell Type RNA - T-cells [nTPM]":"71.1","Single Cell Type RNA - Theca cells [nTPM]":"28.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"32.8","Single Cell Type RNA - Urothelial cells [nTPM]":"64.6"},{"Gene":"ALG2","Gene synonym":["CDG1I","CDGIi","FLJ14511","hALPG2","NET38"],"Ensembl":"ENSG00000119523","Gene description":"ALG2 alpha-1,3\/1,6-mannosyltransferase","Uniprot":["Q9H553"],"Chromosome":"9","Position":"99216425-99221942","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041512","HPA041601"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA041512":"AB_10794380","HPA041601":"AB_10794302"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.44e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.56e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.28e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-1"},"Tissue RNA - adipose tissue [nTPM]":"17.7","Tissue RNA - adrenal gland [nTPM]":"38.2","Tissue RNA - amygdala [nTPM]":"13.4","Tissue RNA - appendix [nTPM]":"19.4","Tissue RNA - basal ganglia [nTPM]":"14.6","Tissue RNA - bone marrow [nTPM]":"23.0","Tissue RNA - breast [nTPM]":"27.1","Tissue RNA - cerebellum [nTPM]":"16.6","Tissue RNA - cerebral cortex [nTPM]":"18.4","Tissue RNA - cervix [nTPM]":"35.1","Tissue RNA - choroid plexus [nTPM]":"19.8","Tissue RNA - colon [nTPM]":"24.9","Tissue RNA - duodenum [nTPM]":"21.9","Tissue RNA - endometrium 1 [nTPM]":"23.8","Tissue RNA - epididymis [nTPM]":"74.0","Tissue RNA - esophagus [nTPM]":"15.1","Tissue RNA - fallopian tube [nTPM]":"29.5","Tissue RNA - gallbladder [nTPM]":"26.2","Tissue RNA - heart muscle [nTPM]":"13.4","Tissue RNA - hippocampal formation [nTPM]":"14.5","Tissue RNA - hypothalamus [nTPM]":"15.0","Tissue RNA - kidney [nTPM]":"34.3","Tissue RNA - liver [nTPM]":"47.4","Tissue RNA - lung [nTPM]":"24.3","Tissue RNA - lymph node [nTPM]":"20.8","Tissue RNA - medulla oblongata [nTPM]":"14.7","Tissue RNA - midbrain [nTPM]":"16.1","Tissue RNA - ovary [nTPM]":"30.2","Tissue RNA - pancreas [nTPM]":"42.0","Tissue RNA - parathyroid gland [nTPM]":"37.0","Tissue RNA - pituitary gland [nTPM]":"21.8","Tissue RNA - placenta [nTPM]":"29.9","Tissue RNA - pons [nTPM]":"15.1","Tissue RNA - prostate [nTPM]":"32.8","Tissue RNA - rectum [nTPM]":"27.3","Tissue RNA - retina [nTPM]":"15.0","Tissue RNA - salivary gland [nTPM]":"37.9","Tissue RNA - seminal vesicle [nTPM]":"34.5","Tissue RNA - skeletal muscle [nTPM]":"15.3","Tissue RNA - skin 1 [nTPM]":"17.9","Tissue RNA - small intestine [nTPM]":"20.5","Tissue RNA - smooth muscle [nTPM]":"24.2","Tissue RNA - spinal cord [nTPM]":"14.8","Tissue RNA - spleen [nTPM]":"17.9","Tissue RNA - stomach 1 [nTPM]":"25.0","Tissue RNA - testis [nTPM]":"19.2","Tissue RNA - thalamus [nTPM]":"14.7","Tissue RNA - thymus [nTPM]":"16.7","Tissue RNA - thyroid gland [nTPM]":"42.3","Tissue RNA - tongue [nTPM]":"13.5","Tissue RNA - tonsil [nTPM]":"27.5","Tissue RNA - urinary bladder [nTPM]":"31.7","Tissue RNA - vagina [nTPM]":"10.9","Tissue RNA - white matter [nTPM]":"16.9","Cell RNA - A-431 [nTPM]":"22.9","Cell RNA - A549 [nTPM]":"28.7","Cell RNA - AF22 [nTPM]":"22.7","Cell RNA - AN3-CA [nTPM]":"34.4","Cell RNA - ASC diff [nTPM]":"82.6","Cell RNA - ASC TERT1 [nTPM]":"52.7","Cell RNA - BEWO [nTPM]":"42.0","Cell RNA - BJ [nTPM]":"46.7","Cell RNA - BJ hTERT+ [nTPM]":"75.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"45.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"39.3","Cell RNA - CACO-2 [nTPM]":"34.9","Cell RNA - CAPAN-2 [nTPM]":"31.2","Cell RNA - Daudi [nTPM]":"24.6","Cell RNA - EFO-21 [nTPM]":"18.8","Cell RNA - fHDF\/TERT166 [nTPM]":"54.3","Cell RNA - GAMG [nTPM]":"60.0","Cell RNA - HaCaT [nTPM]":"85.3","Cell RNA - HAP1 [nTPM]":"37.9","Cell RNA - HBEC3-KT [nTPM]":"49.1","Cell RNA - HBF TERT88 [nTPM]":"45.7","Cell RNA - HDLM-2 [nTPM]":"35.2","Cell RNA - HEK 293 [nTPM]":"16.2","Cell RNA - HEL [nTPM]":"14.4","Cell RNA - HeLa [nTPM]":"23.7","Cell RNA - Hep G2 [nTPM]":"54.0","Cell RNA - HHSteC [nTPM]":"99.7","Cell RNA - HL-60 [nTPM]":"28.2","Cell RNA - HMC-1 [nTPM]":"26.2","Cell RNA - HSkMC [nTPM]":"61.9","Cell RNA - hTCEpi [nTPM]":"65.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"37.7","Cell RNA - hTERT-HME1 [nTPM]":"72.8","Cell RNA - hTERT-RPE1 [nTPM]":"45.8","Cell RNA - HUVEC TERT2 [nTPM]":"52.3","Cell RNA - JURKAT [nTPM]":"15.1","Cell RNA - K-562 [nTPM]":"23.2","Cell RNA - Karpas-707 [nTPM]":"56.2","Cell RNA - LHCN-M2 [nTPM]":"44.7","Cell RNA - MCF7 [nTPM]":"47.8","Cell RNA - MOLT-4 [nTPM]":"12.9","Cell RNA - NB-4 [nTPM]":"29.8","Cell RNA - NTERA-2 [nTPM]":"27.6","Cell RNA - OE19 [nTPM]":"75.0","Cell RNA - PC-3 [nTPM]":"39.6","Cell RNA - REH [nTPM]":"14.0","Cell RNA - RH-30 [nTPM]":"43.4","Cell RNA - RPMI-8226 [nTPM]":"38.1","Cell RNA - RPTEC TERT1 [nTPM]":"65.2","Cell RNA - RT4 [nTPM]":"31.1","Cell RNA - SCLC-21H [nTPM]":"22.5","Cell RNA - SH-SY5Y [nTPM]":"19.3","Cell RNA - SiHa [nTPM]":"33.5","Cell RNA - SK-BR-3 [nTPM]":"63.8","Cell RNA - SK-MEL-30 [nTPM]":"61.6","Cell RNA - SuSa [nTPM]":"33.5","Cell RNA - T-47d [nTPM]":"24.4","Cell RNA - THP-1 [nTPM]":"23.3","Cell RNA - TIME [nTPM]":"38.8","Cell RNA - U-138 MG [nTPM]":"31.4","Cell RNA - U-2 OS [nTPM]":"27.9","Cell RNA - U-2197 [nTPM]":"40.9","Cell RNA - U-251 MG [nTPM]":"28.6","Cell RNA - U-266\/70 [nTPM]":"45.8","Cell RNA - U-266\/84 [nTPM]":"28.0","Cell RNA - U-698 [nTPM]":"10.5","Cell RNA - U-87 MG [nTPM]":"58.6","Cell RNA - U-937 [nTPM]":"20.5","Cell RNA - WM-115 [nTPM]":"16.3","Blood RNA - basophil [nTPM]":"38.7","Blood RNA - classical monocyte [nTPM]":"35.5","Blood RNA - eosinophil [nTPM]":"22.0","Blood RNA - gdT-cell [nTPM]":"33.7","Blood RNA - intermediate monocyte [nTPM]":"28.2","Blood RNA - MAIT T-cell [nTPM]":"49.2","Blood RNA - memory B-cell [nTPM]":"30.8","Blood RNA - memory CD4 T-cell [nTPM]":"32.0","Blood RNA - memory CD8 T-cell [nTPM]":"33.9","Blood RNA - myeloid DC [nTPM]":"45.1","Blood RNA - naive B-cell [nTPM]":"26.3","Blood RNA - naive CD4 T-cell [nTPM]":"27.7","Blood RNA - naive CD8 T-cell [nTPM]":"27.4","Blood RNA - neutrophil [nTPM]":"9.3","Blood RNA - NK-cell [nTPM]":"38.0","Blood RNA - non-classical monocyte [nTPM]":"28.4","Blood RNA - plasmacytoid DC [nTPM]":"79.9","Blood RNA - T-reg [nTPM]":"38.3","Blood RNA - total PBMC [nTPM]":"36.0","Brain RNA - amygdala [nTPM]":"13.4","Brain RNA - basal ganglia [nTPM]":"14.6","Brain RNA - cerebellum [nTPM]":"16.6","Brain RNA - cerebral cortex [nTPM]":"18.4","Brain RNA - hippocampal formation [nTPM]":"14.5","Brain RNA - hypothalamus [nTPM]":"15.0","Brain RNA - medulla oblongata [nTPM]":"14.7","Brain RNA - midbrain [nTPM]":"16.1","Brain RNA - pons [nTPM]":"15.1","Brain RNA - spinal cord [nTPM]":"14.8","Brain RNA - thalamus [nTPM]":"14.7","Brain RNA - white matter [nTPM]":"16.9","Single Cell Type RNA - Adipocytes [nTPM]":"12.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"22.9","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"22.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"23.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"26.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"56.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"11.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"35.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"50.3","Single Cell Type RNA - dendritic cells [nTPM]":"30.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"20.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"36.1","Single Cell Type RNA - Early spermatids [nTPM]":"28.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"30.9","Single Cell Type RNA - Endothelial cells [nTPM]":"19.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.5","Single Cell Type RNA - Erythroid cells [nTPM]":"12.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"35.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"34.2","Single Cell Type RNA - Fibroblasts [nTPM]":"30.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.4","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"14.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.8","Single Cell Type RNA - Hepatocytes [nTPM]":"55.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.1","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.3","Single Cell Type RNA - Ionocytes [nTPM]":"38.7","Single Cell Type RNA - Kupffer cells [nTPM]":"25.8","Single Cell Type RNA - Langerhans cells [nTPM]":"45.4","Single Cell Type RNA - Late spermatids [nTPM]":"20.3","Single Cell Type RNA - Leydig cells [nTPM]":"26.8","Single Cell Type RNA - Macrophages [nTPM]":"23.0","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"64.2","Single Cell Type RNA - Muller glia cells [nTPM]":"15.5","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"31.9","Single Cell Type RNA - Paneth cells [nTPM]":"16.0","Single Cell Type RNA - Peritubular cells [nTPM]":"25.2","Single Cell Type RNA - Plasma cells [nTPM]":"47.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"37.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"36.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.2","Single Cell Type RNA - Spermatocytes [nTPM]":"22.6","Single Cell Type RNA - Spermatogonia [nTPM]":"24.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"23.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"89.2","Single Cell Type RNA - T-cells [nTPM]":"16.6","Single Cell Type RNA - Theca cells [nTPM]":"25.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.8","Single Cell Type RNA - Urothelial cells [nTPM]":"31.3"},{"Gene":"ALG3","Gene synonym":["CDGS4","D16Ertd36e","Not56","NOT56L"],"Ensembl":"ENSG00000214160","Gene description":"ALG3 alpha-1,3- mannosyltransferase","Uniprot":["Q92685"],"Chromosome":"3","Position":"184242301-184249548","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"211.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045103"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045103":"AB_10960547"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.93e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.58e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.67e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.25e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Tissue RNA - adipose tissue [nTPM]":"22.0","Tissue RNA - adrenal gland [nTPM]":"32.6","Tissue RNA - amygdala [nTPM]":"9.3","Tissue RNA - appendix [nTPM]":"15.0","Tissue RNA - basal ganglia [nTPM]":"9.3","Tissue RNA - bone marrow [nTPM]":"15.7","Tissue RNA - breast [nTPM]":"19.7","Tissue RNA - cerebellum [nTPM]":"10.8","Tissue RNA - cerebral cortex [nTPM]":"11.1","Tissue RNA - cervix [nTPM]":"18.1","Tissue RNA - choroid plexus [nTPM]":"13.9","Tissue RNA - colon [nTPM]":"23.8","Tissue RNA - duodenum [nTPM]":"16.9","Tissue RNA - endometrium 1 [nTPM]":"17.5","Tissue RNA - epididymis [nTPM]":"12.5","Tissue RNA - esophagus [nTPM]":"30.5","Tissue RNA - fallopian tube [nTPM]":"15.1","Tissue RNA - gallbladder [nTPM]":"11.6","Tissue RNA - heart muscle [nTPM]":"19.6","Tissue RNA - hippocampal formation [nTPM]":"8.8","Tissue RNA - hypothalamus [nTPM]":"9.7","Tissue RNA - kidney [nTPM]":"18.7","Tissue RNA - liver [nTPM]":"58.0","Tissue RNA - lung [nTPM]":"18.1","Tissue RNA - lymph node [nTPM]":"13.0","Tissue RNA - medulla oblongata [nTPM]":"10.6","Tissue RNA - midbrain [nTPM]":"10.1","Tissue RNA - ovary [nTPM]":"12.7","Tissue RNA - pancreas [nTPM]":"37.1","Tissue RNA - parathyroid gland [nTPM]":"23.1","Tissue RNA - pituitary gland [nTPM]":"14.6","Tissue RNA - placenta [nTPM]":"19.6","Tissue RNA - pons [nTPM]":"11.2","Tissue RNA - prostate [nTPM]":"19.8","Tissue RNA - rectum [nTPM]":"18.3","Tissue RNA - retina [nTPM]":"6.0","Tissue RNA - salivary gland [nTPM]":"26.8","Tissue RNA - seminal vesicle [nTPM]":"13.7","Tissue RNA - skeletal muscle [nTPM]":"30.2","Tissue RNA - skin 1 [nTPM]":"24.9","Tissue RNA - small intestine [nTPM]":"20.4","Tissue RNA - smooth muscle [nTPM]":"16.4","Tissue RNA - spinal cord [nTPM]":"10.0","Tissue RNA - spleen [nTPM]":"20.8","Tissue RNA - stomach 1 [nTPM]":"23.1","Tissue RNA - testis [nTPM]":"25.7","Tissue RNA - thalamus [nTPM]":"10.7","Tissue RNA - thymus [nTPM]":"12.2","Tissue RNA - thyroid gland [nTPM]":"18.4","Tissue RNA - tongue [nTPM]":"14.8","Tissue RNA - tonsil [nTPM]":"14.1","Tissue RNA - urinary bladder [nTPM]":"22.5","Tissue RNA - vagina [nTPM]":"19.8","Tissue RNA - white matter [nTPM]":"10.3","Cell RNA - A-431 [nTPM]":"77.2","Cell RNA - A549 [nTPM]":"67.6","Cell RNA - AF22 [nTPM]":"18.0","Cell RNA - AN3-CA [nTPM]":"59.5","Cell RNA - ASC diff [nTPM]":"70.2","Cell RNA - ASC TERT1 [nTPM]":"39.4","Cell RNA - BEWO [nTPM]":"59.3","Cell RNA - BJ [nTPM]":"40.6","Cell RNA - BJ hTERT+ [nTPM]":"46.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"54.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"47.3","Cell RNA - CACO-2 [nTPM]":"102.8","Cell RNA - CAPAN-2 [nTPM]":"50.9","Cell RNA - Daudi [nTPM]":"67.6","Cell RNA - EFO-21 [nTPM]":"108.4","Cell RNA - fHDF\/TERT166 [nTPM]":"50.8","Cell RNA - GAMG [nTPM]":"112.0","Cell RNA - HaCaT [nTPM]":"90.8","Cell RNA - HAP1 [nTPM]":"64.1","Cell RNA - HBEC3-KT [nTPM]":"90.0","Cell RNA - HBF TERT88 [nTPM]":"34.5","Cell RNA - HDLM-2 [nTPM]":"49.0","Cell RNA - HEK 293 [nTPM]":"76.7","Cell RNA - HEL [nTPM]":"60.8","Cell RNA - HeLa [nTPM]":"49.3","Cell RNA - Hep G2 [nTPM]":"84.7","Cell RNA - HHSteC [nTPM]":"64.3","Cell RNA - HL-60 [nTPM]":"99.5","Cell RNA - HMC-1 [nTPM]":"52.4","Cell RNA - HSkMC [nTPM]":"47.0","Cell RNA - hTCEpi [nTPM]":"74.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"64.8","Cell RNA - hTERT-HME1 [nTPM]":"90.9","Cell RNA - hTERT-RPE1 [nTPM]":"29.4","Cell RNA - HUVEC TERT2 [nTPM]":"30.0","Cell RNA - JURKAT [nTPM]":"46.0","Cell RNA - K-562 [nTPM]":"60.7","Cell RNA - Karpas-707 [nTPM]":"132.6","Cell RNA - LHCN-M2 [nTPM]":"36.1","Cell RNA - MCF7 [nTPM]":"95.8","Cell RNA - MOLT-4 [nTPM]":"48.5","Cell RNA - NB-4 [nTPM]":"83.1","Cell RNA - NTERA-2 [nTPM]":"55.9","Cell RNA - OE19 [nTPM]":"153.3","Cell RNA - PC-3 [nTPM]":"85.8","Cell RNA - REH [nTPM]":"49.9","Cell RNA - RH-30 [nTPM]":"27.5","Cell RNA - RPMI-8226 [nTPM]":"269.7","Cell RNA - RPTEC TERT1 [nTPM]":"63.2","Cell RNA - RT4 [nTPM]":"25.7","Cell RNA - SCLC-21H [nTPM]":"44.3","Cell RNA - SH-SY5Y [nTPM]":"36.7","Cell RNA - SiHa [nTPM]":"37.6","Cell RNA - SK-BR-3 [nTPM]":"147.0","Cell RNA - SK-MEL-30 [nTPM]":"67.5","Cell RNA - SuSa [nTPM]":"21.8","Cell RNA - T-47d [nTPM]":"140.2","Cell RNA - THP-1 [nTPM]":"54.8","Cell RNA - TIME [nTPM]":"24.3","Cell RNA - U-138 MG [nTPM]":"57.2","Cell RNA - U-2 OS [nTPM]":"36.0","Cell RNA - U-2197 [nTPM]":"51.2","Cell RNA - U-251 MG [nTPM]":"88.4","Cell RNA - U-266\/70 [nTPM]":"72.3","Cell RNA - U-266\/84 [nTPM]":"137.8","Cell RNA - U-698 [nTPM]":"71.3","Cell RNA - U-87 MG [nTPM]":"51.5","Cell RNA - U-937 [nTPM]":"129.2","Cell RNA - WM-115 [nTPM]":"52.9","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"60.9","Blood RNA - eosinophil [nTPM]":"14.6","Blood RNA - gdT-cell [nTPM]":"35.8","Blood RNA - intermediate monocyte [nTPM]":"61.1","Blood RNA - MAIT T-cell [nTPM]":"40.5","Blood RNA - memory B-cell [nTPM]":"31.6","Blood RNA - memory CD4 T-cell [nTPM]":"38.3","Blood RNA - memory CD8 T-cell [nTPM]":"36.8","Blood RNA - myeloid DC [nTPM]":"71.4","Blood RNA - naive B-cell [nTPM]":"30.8","Blood RNA - naive CD4 T-cell [nTPM]":"33.9","Blood RNA - naive CD8 T-cell [nTPM]":"33.2","Blood RNA - neutrophil [nTPM]":"2.0","Blood RNA - NK-cell [nTPM]":"48.9","Blood RNA - non-classical monocyte [nTPM]":"51.3","Blood RNA - plasmacytoid DC [nTPM]":"65.3","Blood RNA - T-reg [nTPM]":"44.6","Blood RNA - total PBMC [nTPM]":"41.7","Brain RNA - amygdala [nTPM]":"9.3","Brain RNA - basal ganglia [nTPM]":"9.3","Brain RNA - cerebellum [nTPM]":"10.8","Brain RNA - cerebral cortex [nTPM]":"11.1","Brain RNA - hippocampal formation [nTPM]":"8.8","Brain RNA - hypothalamus [nTPM]":"9.7","Brain RNA - medulla oblongata [nTPM]":"10.6","Brain RNA - midbrain [nTPM]":"10.1","Brain RNA - pons [nTPM]":"11.2","Brain RNA - spinal cord [nTPM]":"10.0","Brain RNA - thalamus [nTPM]":"10.7","Brain RNA - white matter [nTPM]":"10.3","Single Cell Type RNA - Adipocytes [nTPM]":"14.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.1","Single Cell Type RNA - Astrocytes [nTPM]":"4.6","Single Cell Type RNA - B-cells [nTPM]":"24.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"25.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"28.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"61.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.2","Single Cell Type RNA - Bipolar cells [nTPM]":"10.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"24.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"43.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"79.2","Single Cell Type RNA - dendritic cells [nTPM]":"21.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"62.3","Single Cell Type RNA - Early spermatids [nTPM]":"95.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.7","Single Cell Type RNA - Endothelial cells [nTPM]":"18.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.5","Single Cell Type RNA - Erythroid cells [nTPM]":"24.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"63.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"100.4","Single Cell Type RNA - Fibroblasts [nTPM]":"22.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"25.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.5","Single Cell Type RNA - granulocytes [nTPM]":"12.7","Single Cell Type RNA - Granulosa cells [nTPM]":"16.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.5","Single Cell Type RNA - Hepatocytes [nTPM]":"51.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"69.8","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"33.3","Single Cell Type RNA - Ionocytes [nTPM]":"50.8","Single Cell Type RNA - Kupffer cells [nTPM]":"24.9","Single Cell Type RNA - Langerhans cells [nTPM]":"15.5","Single Cell Type RNA - Late spermatids [nTPM]":"211.5","Single Cell Type RNA - Leydig cells [nTPM]":"12.5","Single Cell Type RNA - Macrophages [nTPM]":"25.8","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"21.2","Single Cell Type RNA - Muller glia cells [nTPM]":"13.7","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"44.6","Single Cell Type RNA - Paneth cells [nTPM]":"22.0","Single Cell Type RNA - Peritubular cells [nTPM]":"15.1","Single Cell Type RNA - Plasma cells [nTPM]":"63.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"47.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"39.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"31.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.0","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"34.6","Single Cell Type RNA - Spermatocytes [nTPM]":"29.7","Single Cell Type RNA - Spermatogonia [nTPM]":"34.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"39.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"65.8","Single Cell Type RNA - T-cells [nTPM]":"17.6","Single Cell Type RNA - Theca cells [nTPM]":"23.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"45.6","Single Cell Type RNA - Urothelial cells [nTPM]":"29.1"},{"Gene":"ALG6","Gene synonym":[],"Ensembl":"ENSG00000088035","Gene description":"ALG6 alpha-1,3-glucosyltransferase","Uniprot":["Q9Y672"],"Chromosome":"1","Position":"63367575-63438553","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"NTERA-2":"7.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062536","HPA076130"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA062536":"AB_2684792","HPA076130":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.86e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.46e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.63e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.5","Tissue RNA - adrenal gland [nTPM]":"4.5","Tissue RNA - amygdala [nTPM]":"1.1","Tissue RNA - appendix [nTPM]":"1.1","Tissue RNA - basal ganglia [nTPM]":"1.3","Tissue RNA - bone marrow [nTPM]":"1.4","Tissue RNA - breast [nTPM]":"3.4","Tissue RNA - cerebellum [nTPM]":"1.9","Tissue RNA - cerebral cortex [nTPM]":"1.4","Tissue RNA - cervix [nTPM]":"3.7","Tissue RNA - choroid plexus [nTPM]":"1.0","Tissue RNA - colon [nTPM]":"3.8","Tissue RNA - duodenum [nTPM]":"1.1","Tissue RNA - endometrium 1 [nTPM]":"2.9","Tissue RNA - epididymis [nTPM]":"1.4","Tissue RNA - esophagus [nTPM]":"6.1","Tissue RNA - fallopian tube [nTPM]":"3.0","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"2.1","Tissue RNA - hippocampal formation [nTPM]":"1.1","Tissue RNA - hypothalamus [nTPM]":"1.2","Tissue RNA - kidney [nTPM]":"3.0","Tissue RNA - liver [nTPM]":"4.6","Tissue RNA - lung [nTPM]":"2.7","Tissue RNA - lymph node [nTPM]":"1.9","Tissue RNA - medulla oblongata [nTPM]":"1.1","Tissue RNA - midbrain [nTPM]":"1.2","Tissue RNA - ovary [nTPM]":"3.2","Tissue RNA - pancreas [nTPM]":"3.3","Tissue RNA - parathyroid gland [nTPM]":"1.4","Tissue RNA - pituitary gland [nTPM]":"2.0","Tissue RNA - placenta [nTPM]":"1.0","Tissue RNA - pons [nTPM]":"1.1","Tissue RNA - prostate [nTPM]":"3.1","Tissue RNA - rectum [nTPM]":"1.2","Tissue RNA - retina [nTPM]":"1.2","Tissue RNA - salivary gland [nTPM]":"4.3","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"2.8","Tissue RNA - skin 1 [nTPM]":"5.1","Tissue RNA - small intestine [nTPM]":"4.4","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"5.2","Tissue RNA - stomach 1 [nTPM]":"3.2","Tissue RNA - testis [nTPM]":"2.2","Tissue RNA - thalamus [nTPM]":"1.1","Tissue RNA - thymus [nTPM]":"2.0","Tissue RNA - thyroid gland [nTPM]":"3.1","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"1.6","Tissue RNA - urinary bladder [nTPM]":"3.1","Tissue RNA - vagina [nTPM]":"4.2","Tissue RNA - white matter [nTPM]":"1.4","Cell RNA - A-431 [nTPM]":"0.5","Cell RNA - A549 [nTPM]":"1.3","Cell RNA - AF22 [nTPM]":"1.3","Cell RNA - AN3-CA [nTPM]":"1.2","Cell RNA - ASC diff [nTPM]":"1.8","Cell RNA - ASC TERT1 [nTPM]":"1.3","Cell RNA - BEWO [nTPM]":"2.6","Cell RNA - BJ [nTPM]":"0.9","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"2.0","Cell RNA - CAPAN-2 [nTPM]":"0.6","Cell RNA - Daudi [nTPM]":"2.7","Cell RNA - EFO-21 [nTPM]":"1.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.7","Cell RNA - GAMG [nTPM]":"1.5","Cell RNA - HaCaT [nTPM]":"1.0","Cell RNA - HAP1 [nTPM]":"2.0","Cell RNA - HBEC3-KT [nTPM]":"1.0","Cell RNA - HBF TERT88 [nTPM]":"1.4","Cell RNA - HDLM-2 [nTPM]":"2.4","Cell RNA - HEK 293 [nTPM]":"4.2","Cell RNA - HEL [nTPM]":"2.2","Cell RNA - HeLa [nTPM]":"1.5","Cell RNA - Hep G2 [nTPM]":"2.4","Cell RNA - HHSteC [nTPM]":"0.6","Cell RNA - HL-60 [nTPM]":"2.8","Cell RNA - HMC-1 [nTPM]":"2.4","Cell RNA - HSkMC [nTPM]":"0.9","Cell RNA - hTCEpi [nTPM]":"0.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.9","Cell RNA - hTERT-HME1 [nTPM]":"0.6","Cell RNA - hTERT-RPE1 [nTPM]":"0.7","Cell RNA - HUVEC TERT2 [nTPM]":"2.0","Cell RNA - JURKAT [nTPM]":"2.3","Cell RNA - K-562 [nTPM]":"2.2","Cell RNA - Karpas-707 [nTPM]":"1.3","Cell RNA - LHCN-M2 [nTPM]":"1.0","Cell RNA - MCF7 [nTPM]":"2.5","Cell RNA - MOLT-4 [nTPM]":"1.7","Cell RNA - NB-4 [nTPM]":"2.4","Cell RNA - NTERA-2 [nTPM]":"7.6","Cell RNA - OE19 [nTPM]":"1.3","Cell RNA - PC-3 [nTPM]":"2.3","Cell RNA - REH [nTPM]":"1.8","Cell RNA - RH-30 [nTPM]":"1.6","Cell RNA - RPMI-8226 [nTPM]":"2.1","Cell RNA - RPTEC TERT1 [nTPM]":"1.6","Cell RNA - RT4 [nTPM]":"2.2","Cell RNA - SCLC-21H [nTPM]":"1.5","Cell RNA - SH-SY5Y [nTPM]":"0.8","Cell RNA - SiHa [nTPM]":"2.3","Cell RNA - SK-BR-3 [nTPM]":"3.2","Cell RNA - SK-MEL-30 [nTPM]":"2.3","Cell RNA - SuSa [nTPM]":"2.9","Cell RNA - T-47d [nTPM]":"0.9","Cell RNA - THP-1 [nTPM]":"2.1","Cell RNA - TIME [nTPM]":"0.9","Cell RNA - U-138 MG [nTPM]":"0.6","Cell RNA - U-2 OS [nTPM]":"0.6","Cell RNA - U-2197 [nTPM]":"1.8","Cell RNA - U-251 MG [nTPM]":"1.5","Cell RNA - U-266\/70 [nTPM]":"1.7","Cell RNA - U-266\/84 [nTPM]":"1.7","Cell RNA - U-698 [nTPM]":"1.7","Cell RNA - U-87 MG [nTPM]":"1.2","Cell RNA - U-937 [nTPM]":"3.3","Cell RNA - WM-115 [nTPM]":"2.4","Blood RNA - basophil [nTPM]":"1.3","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"1.1","Brain RNA - basal ganglia [nTPM]":"1.3","Brain RNA - cerebellum [nTPM]":"1.9","Brain RNA - cerebral cortex [nTPM]":"1.4","Brain RNA - hippocampal formation [nTPM]":"1.1","Brain RNA - hypothalamus [nTPM]":"1.2","Brain RNA - medulla oblongata [nTPM]":"1.1","Brain RNA - midbrain [nTPM]":"1.2","Brain RNA - pons [nTPM]":"1.1","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"1.1","Brain RNA - white matter [nTPM]":"1.4","Single Cell Type RNA - Adipocytes [nTPM]":"9.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"9.8","Single Cell Type RNA - B-cells [nTPM]":"12.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"24.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Bipolar cells [nTPM]":"6.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"22.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"42.1","Single Cell Type RNA - dendritic cells [nTPM]":"10.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"12.4","Single Cell Type RNA - Early spermatids [nTPM]":"2.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.0","Single Cell Type RNA - Endothelial cells [nTPM]":"8.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"9.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"28.5","Single Cell Type RNA - Fibroblasts [nTPM]":"8.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.0","Single Cell Type RNA - granulocytes [nTPM]":"8.9","Single Cell Type RNA - Granulosa cells [nTPM]":"12.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.2","Single Cell Type RNA - Hepatocytes [nTPM]":"11.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.5","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"19.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.8","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"7.1","Single Cell Type RNA - Langerhans cells [nTPM]":"8.8","Single Cell Type RNA - Late spermatids [nTPM]":"2.0","Single Cell Type RNA - Leydig cells [nTPM]":"6.8","Single Cell Type RNA - Macrophages [nTPM]":"9.1","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"4.8","Single Cell Type RNA - Muller glia cells [nTPM]":"5.5","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.0","Single Cell Type RNA - Paneth cells [nTPM]":"3.6","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"11.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.6","Single Cell Type RNA - Spermatocytes [nTPM]":"16.2","Single Cell Type RNA - Spermatogonia [nTPM]":"15.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"26.8","Single Cell Type RNA - T-cells [nTPM]":"15.1","Single Cell Type RNA - Theca cells [nTPM]":"10.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.5","Single Cell Type RNA - Urothelial cells [nTPM]":"7.4"},{"Gene":"ALG8","Gene synonym":["MGC2840"],"Ensembl":"ENSG00000159063","Gene description":"ALG8 alpha-1,3-glucosyltransferase","Uniprot":["Q9BVK2"],"Chromosome":"11","Position":"78095244-78139660","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"105.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051898"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA051898":"AB_2681656"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.37e-2"},"Tissue RNA - adipose tissue [nTPM]":"22.8","Tissue RNA - adrenal gland [nTPM]":"33.0","Tissue RNA - amygdala [nTPM]":"12.7","Tissue RNA - appendix [nTPM]":"13.4","Tissue RNA - basal ganglia [nTPM]":"14.3","Tissue RNA - bone marrow [nTPM]":"9.2","Tissue RNA - breast [nTPM]":"25.6","Tissue RNA - cerebellum [nTPM]":"13.9","Tissue RNA - cerebral cortex [nTPM]":"16.4","Tissue RNA - cervix [nTPM]":"18.7","Tissue RNA - choroid plexus [nTPM]":"15.4","Tissue RNA - colon [nTPM]":"17.5","Tissue RNA - duodenum [nTPM]":"13.3","Tissue RNA - endometrium 1 [nTPM]":"15.9","Tissue RNA - epididymis [nTPM]":"33.2","Tissue RNA - esophagus [nTPM]":"19.0","Tissue RNA - fallopian tube [nTPM]":"18.8","Tissue RNA - gallbladder [nTPM]":"12.0","Tissue RNA - heart muscle [nTPM]":"17.9","Tissue RNA - hippocampal formation [nTPM]":"12.9","Tissue RNA - hypothalamus [nTPM]":"13.3","Tissue RNA - kidney [nTPM]":"24.9","Tissue RNA - liver [nTPM]":"47.1","Tissue RNA - lung [nTPM]":"15.0","Tissue RNA - lymph node [nTPM]":"14.6","Tissue RNA - medulla oblongata [nTPM]":"14.1","Tissue RNA - midbrain [nTPM]":"13.1","Tissue RNA - ovary [nTPM]":"22.1","Tissue RNA - pancreas [nTPM]":"23.8","Tissue RNA - parathyroid gland [nTPM]":"23.7","Tissue RNA - pituitary gland [nTPM]":"19.8","Tissue RNA - placenta [nTPM]":"18.7","Tissue RNA - pons [nTPM]":"13.8","Tissue RNA - prostate [nTPM]":"19.1","Tissue RNA - rectum [nTPM]":"21.8","Tissue RNA - retina [nTPM]":"10.4","Tissue RNA - salivary gland [nTPM]":"21.7","Tissue RNA - seminal vesicle [nTPM]":"18.0","Tissue RNA - skeletal muscle [nTPM]":"12.1","Tissue RNA - skin 1 [nTPM]":"16.6","Tissue RNA - small intestine [nTPM]":"15.5","Tissue RNA - smooth muscle [nTPM]":"16.4","Tissue RNA - spinal cord [nTPM]":"13.5","Tissue RNA - spleen [nTPM]":"18.3","Tissue RNA - stomach 1 [nTPM]":"20.2","Tissue RNA - testis [nTPM]":"43.5","Tissue RNA - thalamus [nTPM]":"13.1","Tissue RNA - thymus [nTPM]":"17.8","Tissue RNA - thyroid gland [nTPM]":"22.4","Tissue RNA - tongue [nTPM]":"8.9","Tissue RNA - tonsil [nTPM]":"19.8","Tissue RNA - urinary bladder [nTPM]":"18.4","Tissue RNA - vagina [nTPM]":"16.0","Tissue RNA - white matter [nTPM]":"15.2","Cell RNA - A-431 [nTPM]":"27.8","Cell RNA - A549 [nTPM]":"74.4","Cell RNA - AF22 [nTPM]":"62.8","Cell RNA - AN3-CA [nTPM]":"56.6","Cell RNA - ASC diff [nTPM]":"63.7","Cell RNA - ASC TERT1 [nTPM]":"42.5","Cell RNA - BEWO [nTPM]":"37.6","Cell RNA - BJ [nTPM]":"38.6","Cell RNA - BJ hTERT+ [nTPM]":"57.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"68.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"67.4","Cell RNA - CACO-2 [nTPM]":"127.9","Cell RNA - CAPAN-2 [nTPM]":"102.0","Cell RNA - Daudi [nTPM]":"61.4","Cell RNA - EFO-21 [nTPM]":"74.5","Cell RNA - fHDF\/TERT166 [nTPM]":"51.5","Cell RNA - GAMG [nTPM]":"92.3","Cell RNA - HaCaT [nTPM]":"86.5","Cell RNA - HAP1 [nTPM]":"87.0","Cell RNA - HBEC3-KT [nTPM]":"56.5","Cell RNA - HBF TERT88 [nTPM]":"111.9","Cell RNA - HDLM-2 [nTPM]":"46.3","Cell RNA - HEK 293 [nTPM]":"50.8","Cell RNA - HEL [nTPM]":"74.3","Cell RNA - HeLa [nTPM]":"56.5","Cell RNA - Hep G2 [nTPM]":"62.2","Cell RNA - HHSteC [nTPM]":"38.9","Cell RNA - HL-60 [nTPM]":"71.8","Cell RNA - HMC-1 [nTPM]":"39.6","Cell RNA - HSkMC [nTPM]":"34.4","Cell RNA - hTCEpi [nTPM]":"36.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"81.8","Cell RNA - hTERT-HME1 [nTPM]":"37.9","Cell RNA - hTERT-RPE1 [nTPM]":"37.5","Cell RNA - HUVEC TERT2 [nTPM]":"50.3","Cell RNA - JURKAT [nTPM]":"58.0","Cell RNA - K-562 [nTPM]":"98.2","Cell RNA - Karpas-707 [nTPM]":"65.8","Cell RNA - LHCN-M2 [nTPM]":"97.7","Cell RNA - MCF7 [nTPM]":"38.6","Cell RNA - MOLT-4 [nTPM]":"53.3","Cell RNA - NB-4 [nTPM]":"61.9","Cell RNA - NTERA-2 [nTPM]":"81.9","Cell RNA - OE19 [nTPM]":"200.5","Cell RNA - PC-3 [nTPM]":"38.1","Cell RNA - REH [nTPM]":"63.6","Cell RNA - RH-30 [nTPM]":"32.6","Cell RNA - RPMI-8226 [nTPM]":"168.3","Cell RNA - RPTEC TERT1 [nTPM]":"70.0","Cell RNA - RT4 [nTPM]":"40.4","Cell RNA - SCLC-21H [nTPM]":"20.2","Cell RNA - SH-SY5Y [nTPM]":"44.8","Cell RNA - SiHa [nTPM]":"62.0","Cell RNA - SK-BR-3 [nTPM]":"102.2","Cell RNA - SK-MEL-30 [nTPM]":"29.4","Cell RNA - SuSa [nTPM]":"65.6","Cell RNA - T-47d [nTPM]":"106.5","Cell RNA - THP-1 [nTPM]":"50.8","Cell RNA - TIME [nTPM]":"32.0","Cell RNA - U-138 MG [nTPM]":"43.5","Cell RNA - U-2 OS [nTPM]":"50.6","Cell RNA - U-2197 [nTPM]":"102.5","Cell RNA - U-251 MG [nTPM]":"35.1","Cell RNA - U-266\/70 [nTPM]":"46.6","Cell RNA - U-266\/84 [nTPM]":"88.0","Cell RNA - U-698 [nTPM]":"80.3","Cell RNA - U-87 MG [nTPM]":"26.7","Cell RNA - U-937 [nTPM]":"71.4","Cell RNA - WM-115 [nTPM]":"84.4","Blood RNA - basophil [nTPM]":"1.2","Blood RNA - classical monocyte [nTPM]":"30.0","Blood RNA - eosinophil [nTPM]":"5.4","Blood RNA - gdT-cell [nTPM]":"25.1","Blood RNA - intermediate monocyte [nTPM]":"34.5","Blood RNA - MAIT T-cell [nTPM]":"29.1","Blood RNA - memory B-cell [nTPM]":"37.2","Blood RNA - memory CD4 T-cell [nTPM]":"25.5","Blood RNA - memory CD8 T-cell [nTPM]":"25.7","Blood RNA - myeloid DC [nTPM]":"34.2","Blood RNA - naive B-cell [nTPM]":"31.3","Blood RNA - naive CD4 T-cell [nTPM]":"29.7","Blood RNA - naive CD8 T-cell [nTPM]":"26.2","Blood RNA - neutrophil [nTPM]":"2.6","Blood RNA - NK-cell [nTPM]":"29.1","Blood RNA - non-classical monocyte [nTPM]":"39.9","Blood RNA - plasmacytoid DC [nTPM]":"33.1","Blood RNA - T-reg [nTPM]":"22.5","Blood RNA - total PBMC [nTPM]":"27.6","Brain RNA - amygdala [nTPM]":"12.7","Brain RNA - basal ganglia [nTPM]":"14.3","Brain RNA - cerebellum [nTPM]":"13.9","Brain RNA - cerebral cortex [nTPM]":"16.4","Brain RNA - hippocampal formation [nTPM]":"12.9","Brain RNA - hypothalamus [nTPM]":"13.3","Brain RNA - medulla oblongata [nTPM]":"14.1","Brain RNA - midbrain [nTPM]":"13.1","Brain RNA - pons [nTPM]":"13.8","Brain RNA - spinal cord [nTPM]":"13.5","Brain RNA - thalamus [nTPM]":"13.1","Brain RNA - white matter [nTPM]":"15.2","Single Cell Type RNA - Adipocytes [nTPM]":"11.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.6","Single Cell Type RNA - Astrocytes [nTPM]":"12.4","Single Cell Type RNA - B-cells [nTPM]":"21.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"49.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.2","Single Cell Type RNA - Bipolar cells [nTPM]":"14.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"35.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"53.8","Single Cell Type RNA - dendritic cells [nTPM]":"9.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"24.4","Single Cell Type RNA - Early spermatids [nTPM]":"18.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.9","Single Cell Type RNA - Endothelial cells [nTPM]":"17.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.8","Single Cell Type RNA - Erythroid cells [nTPM]":"9.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"21.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"59.5","Single Cell Type RNA - Fibroblasts [nTPM]":"19.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.8","Single Cell Type RNA - granulocytes [nTPM]":"11.4","Single Cell Type RNA - Granulosa cells [nTPM]":"36.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.3","Single Cell Type RNA - Hepatocytes [nTPM]":"40.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"31.4","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.9","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"17.0","Single Cell Type RNA - Langerhans cells [nTPM]":"10.8","Single Cell Type RNA - Late spermatids [nTPM]":"14.0","Single Cell Type RNA - Leydig cells [nTPM]":"18.0","Single Cell Type RNA - Macrophages [nTPM]":"15.3","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"12.3","Single Cell Type RNA - Muller glia cells [nTPM]":"8.2","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.7","Single Cell Type RNA - Paneth cells [nTPM]":"6.4","Single Cell Type RNA - Peritubular cells [nTPM]":"15.8","Single Cell Type RNA - Plasma cells [nTPM]":"43.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.6","Single Cell Type RNA - Spermatocytes [nTPM]":"105.0","Single Cell Type RNA - Spermatogonia [nTPM]":"37.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"32.7","Single Cell Type RNA - T-cells [nTPM]":"15.2","Single Cell Type RNA - Theca cells [nTPM]":"16.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.8","Single Cell Type RNA - Urothelial cells [nTPM]":"15.2"},{"Gene":"ALG9","Gene synonym":["DIBD1"],"Ensembl":"ENSG00000086848","Gene description":"ALG9 alpha-1,2-mannosyltransferase","Uniprot":["Q9H6U8"],"Chromosome":"11","Position":"111782195-111871581","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"26.6","Inhibitory neurons":"31.8","Oligodendrocytes":"31.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038575"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA038575":"AB_10672718"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.75e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.29e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Tissue RNA - adipose tissue [nTPM]":"14.0","Tissue RNA - adrenal gland [nTPM]":"9.7","Tissue RNA - amygdala [nTPM]":"6.3","Tissue RNA - appendix [nTPM]":"8.6","Tissue RNA - basal ganglia [nTPM]":"7.1","Tissue RNA - bone marrow [nTPM]":"7.8","Tissue RNA - breast [nTPM]":"12.4","Tissue RNA - cerebellum [nTPM]":"8.2","Tissue RNA - cerebral cortex [nTPM]":"7.8","Tissue RNA - cervix [nTPM]":"12.9","Tissue RNA - choroid plexus [nTPM]":"6.3","Tissue RNA - colon [nTPM]":"10.9","Tissue RNA - duodenum [nTPM]":"12.1","Tissue RNA - endometrium 1 [nTPM]":"11.5","Tissue RNA - epididymis [nTPM]":"10.9","Tissue RNA - esophagus [nTPM]":"11.4","Tissue RNA - fallopian tube [nTPM]":"9.2","Tissue RNA - gallbladder [nTPM]":"7.9","Tissue RNA - heart muscle [nTPM]":"10.1","Tissue RNA - hippocampal formation [nTPM]":"6.3","Tissue RNA - hypothalamus [nTPM]":"6.6","Tissue RNA - kidney [nTPM]":"9.5","Tissue RNA - liver [nTPM]":"13.4","Tissue RNA - lung [nTPM]":"9.6","Tissue RNA - lymph node [nTPM]":"6.6","Tissue RNA - medulla oblongata [nTPM]":"6.5","Tissue RNA - midbrain [nTPM]":"6.8","Tissue RNA - ovary [nTPM]":"12.5","Tissue RNA - pancreas [nTPM]":"19.7","Tissue RNA - parathyroid gland [nTPM]":"12.7","Tissue RNA - pituitary gland [nTPM]":"10.0","Tissue RNA - placenta [nTPM]":"9.6","Tissue RNA - pons [nTPM]":"6.7","Tissue RNA - prostate [nTPM]":"9.6","Tissue RNA - rectum [nTPM]":"10.3","Tissue RNA - retina [nTPM]":"12.0","Tissue RNA - salivary gland [nTPM]":"17.5","Tissue RNA - seminal vesicle [nTPM]":"11.3","Tissue RNA - skeletal muscle [nTPM]":"9.1","Tissue RNA - skin 1 [nTPM]":"15.2","Tissue RNA - small intestine [nTPM]":"10.2","Tissue RNA - smooth muscle [nTPM]":"11.1","Tissue RNA - spinal cord [nTPM]":"5.6","Tissue RNA - spleen [nTPM]":"8.4","Tissue RNA - stomach 1 [nTPM]":"12.0","Tissue RNA - testis [nTPM]":"13.6","Tissue RNA - thalamus [nTPM]":"6.1","Tissue RNA - thymus [nTPM]":"9.8","Tissue RNA - thyroid gland [nTPM]":"12.3","Tissue RNA - tongue [nTPM]":"8.3","Tissue RNA - tonsil [nTPM]":"9.2","Tissue RNA - urinary bladder [nTPM]":"11.3","Tissue RNA - vagina [nTPM]":"11.1","Tissue RNA - white matter [nTPM]":"6.4","Cell RNA - A-431 [nTPM]":"16.6","Cell RNA - A549 [nTPM]":"16.5","Cell RNA - AF22 [nTPM]":"30.7","Cell RNA - AN3-CA [nTPM]":"31.1","Cell RNA - ASC diff [nTPM]":"19.0","Cell RNA - ASC TERT1 [nTPM]":"18.0","Cell RNA - BEWO [nTPM]":"23.7","Cell RNA - BJ [nTPM]":"20.5","Cell RNA - BJ hTERT+ [nTPM]":"16.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.9","Cell RNA - CACO-2 [nTPM]":"28.7","Cell RNA - CAPAN-2 [nTPM]":"27.4","Cell RNA - Daudi [nTPM]":"27.1","Cell RNA - EFO-21 [nTPM]":"28.7","Cell RNA - fHDF\/TERT166 [nTPM]":"23.8","Cell RNA - GAMG [nTPM]":"21.4","Cell RNA - HaCaT [nTPM]":"29.8","Cell RNA - HAP1 [nTPM]":"16.6","Cell RNA - HBEC3-KT [nTPM]":"25.4","Cell RNA - HBF TERT88 [nTPM]":"23.4","Cell RNA - HDLM-2 [nTPM]":"20.2","Cell RNA - HEK 293 [nTPM]":"12.2","Cell RNA - HEL [nTPM]":"19.7","Cell RNA - HeLa [nTPM]":"8.6","Cell RNA - Hep G2 [nTPM]":"21.2","Cell RNA - HHSteC [nTPM]":"22.0","Cell RNA - HL-60 [nTPM]":"22.2","Cell RNA - HMC-1 [nTPM]":"13.6","Cell RNA - HSkMC [nTPM]":"15.5","Cell RNA - hTCEpi [nTPM]":"17.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"17.7","Cell RNA - hTERT-HME1 [nTPM]":"17.8","Cell RNA - hTERT-RPE1 [nTPM]":"24.2","Cell RNA - HUVEC TERT2 [nTPM]":"16.2","Cell RNA - JURKAT [nTPM]":"20.2","Cell RNA - K-562 [nTPM]":"20.3","Cell RNA - Karpas-707 [nTPM]":"41.0","Cell RNA - LHCN-M2 [nTPM]":"28.4","Cell RNA - MCF7 [nTPM]":"12.5","Cell RNA - MOLT-4 [nTPM]":"22.2","Cell RNA - NB-4 [nTPM]":"20.3","Cell RNA - NTERA-2 [nTPM]":"10.7","Cell RNA - OE19 [nTPM]":"23.3","Cell RNA - PC-3 [nTPM]":"15.9","Cell RNA - REH [nTPM]":"20.4","Cell RNA - RH-30 [nTPM]":"26.9","Cell RNA - RPMI-8226 [nTPM]":"51.5","Cell RNA - RPTEC TERT1 [nTPM]":"18.5","Cell RNA - RT4 [nTPM]":"13.7","Cell RNA - SCLC-21H [nTPM]":"15.0","Cell RNA - SH-SY5Y [nTPM]":"25.4","Cell RNA - SiHa [nTPM]":"18.0","Cell RNA - SK-BR-3 [nTPM]":"28.0","Cell RNA - SK-MEL-30 [nTPM]":"11.4","Cell RNA - SuSa [nTPM]":"21.6","Cell RNA - T-47d [nTPM]":"29.0","Cell RNA - THP-1 [nTPM]":"9.3","Cell RNA - TIME [nTPM]":"16.9","Cell RNA - U-138 MG [nTPM]":"35.0","Cell RNA - U-2 OS [nTPM]":"25.2","Cell RNA - U-2197 [nTPM]":"17.1","Cell RNA - U-251 MG [nTPM]":"22.6","Cell RNA - U-266\/70 [nTPM]":"13.3","Cell RNA - U-266\/84 [nTPM]":"10.2","Cell RNA - U-698 [nTPM]":"24.4","Cell RNA - U-87 MG [nTPM]":"15.1","Cell RNA - U-937 [nTPM]":"27.4","Cell RNA - WM-115 [nTPM]":"24.7","Blood RNA - basophil [nTPM]":"4.5","Blood RNA - classical monocyte [nTPM]":"3.1","Blood RNA - eosinophil [nTPM]":"3.8","Blood RNA - gdT-cell [nTPM]":"4.0","Blood RNA - intermediate monocyte [nTPM]":"4.5","Blood RNA - MAIT T-cell [nTPM]":"4.7","Blood RNA - memory B-cell [nTPM]":"4.0","Blood RNA - memory CD4 T-cell [nTPM]":"4.1","Blood RNA - memory CD8 T-cell [nTPM]":"4.6","Blood RNA - myeloid DC [nTPM]":"5.2","Blood RNA - naive B-cell [nTPM]":"3.1","Blood RNA - naive CD4 T-cell [nTPM]":"5.8","Blood RNA - naive CD8 T-cell [nTPM]":"3.6","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"4.2","Blood RNA - non-classical monocyte [nTPM]":"4.0","Blood RNA - plasmacytoid DC [nTPM]":"5.6","Blood RNA - T-reg [nTPM]":"4.5","Blood RNA - total PBMC [nTPM]":"3.3","Brain RNA - amygdala [nTPM]":"6.3","Brain RNA - basal ganglia [nTPM]":"7.1","Brain RNA - cerebellum [nTPM]":"8.2","Brain RNA - cerebral cortex [nTPM]":"7.8","Brain RNA - hippocampal formation [nTPM]":"6.3","Brain RNA - hypothalamus [nTPM]":"6.6","Brain RNA - medulla oblongata [nTPM]":"6.5","Brain RNA - midbrain [nTPM]":"6.8","Brain RNA - pons [nTPM]":"6.7","Brain RNA - spinal cord [nTPM]":"5.6","Brain RNA - thalamus [nTPM]":"6.1","Brain RNA - white matter [nTPM]":"6.4","Single Cell Type RNA - Adipocytes [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.4","Single Cell Type RNA - Astrocytes [nTPM]":"21.5","Single Cell Type RNA - B-cells [nTPM]":"5.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"8.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"3.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.5","Single Cell Type RNA - dendritic cells [nTPM]":"4.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.5","Single Cell Type RNA - Early spermatids [nTPM]":"5.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.2","Single Cell Type RNA - Endothelial cells [nTPM]":"4.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"6.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"26.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.6","Single Cell Type RNA - Fibroblasts [nTPM]":"4.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"5.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"6.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.2","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"31.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"1.9","Single Cell Type RNA - Late spermatids [nTPM]":"4.3","Single Cell Type RNA - Leydig cells [nTPM]":"4.7","Single Cell Type RNA - Macrophages [nTPM]":"3.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"3.1","Single Cell Type RNA - Muller glia cells [nTPM]":"4.9","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"21.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"31.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.5","Single Cell Type RNA - Paneth cells [nTPM]":"2.9","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"22.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.4","Single Cell Type RNA - Spermatocytes [nTPM]":"4.2","Single Cell Type RNA - Spermatogonia [nTPM]":"5.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.0","Single Cell Type RNA - T-cells [nTPM]":"5.8","Single Cell Type RNA - Theca cells [nTPM]":"2.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.4","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"ALKBH8","Gene synonym":["MGC10235","TRM9","TRMT9A"],"Ensembl":"ENSG00000137760","Gene description":"AlkB homolog 8, tRNA methyltransferase","Uniprot":["Q96BT7"],"Chromosome":"11","Position":"107502727-107565742","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Methyltransferase","Multifunctional enzyme","RNA-binding","Transferase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"25.2","Inhibitory neurons":"27.4","Oligodendrocyte precursor cells":"23.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038724","HPA038725","HPA061514"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA038724":"AB_2676176","HPA038725":"AB_10674838","HPA061514":"AB_2684547"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.1","Tissue RNA - adrenal gland [nTPM]":"2.9","Tissue RNA - amygdala [nTPM]":"2.4","Tissue RNA - appendix [nTPM]":"4.0","Tissue RNA - basal ganglia [nTPM]":"3.0","Tissue RNA - bone marrow [nTPM]":"3.3","Tissue RNA - breast [nTPM]":"5.0","Tissue RNA - cerebellum [nTPM]":"2.6","Tissue RNA - cerebral cortex [nTPM]":"2.8","Tissue RNA - cervix [nTPM]":"2.9","Tissue RNA - choroid plexus [nTPM]":"1.7","Tissue RNA - colon [nTPM]":"3.0","Tissue RNA - duodenum [nTPM]":"3.2","Tissue RNA - endometrium 1 [nTPM]":"3.8","Tissue RNA - epididymis [nTPM]":"3.2","Tissue RNA - esophagus [nTPM]":"3.1","Tissue RNA - fallopian tube [nTPM]":"2.9","Tissue RNA - gallbladder [nTPM]":"2.8","Tissue RNA - heart muscle [nTPM]":"3.8","Tissue RNA - hippocampal formation [nTPM]":"2.4","Tissue RNA - hypothalamus [nTPM]":"2.6","Tissue RNA - kidney [nTPM]":"3.9","Tissue RNA - liver [nTPM]":"4.5","Tissue RNA - lung [nTPM]":"3.6","Tissue RNA - lymph node [nTPM]":"6.0","Tissue RNA - medulla oblongata [nTPM]":"2.2","Tissue RNA - midbrain [nTPM]":"2.6","Tissue RNA - ovary [nTPM]":"4.4","Tissue RNA - pancreas [nTPM]":"2.3","Tissue RNA - parathyroid gland [nTPM]":"4.1","Tissue RNA - pituitary gland [nTPM]":"1.7","Tissue RNA - placenta [nTPM]":"3.3","Tissue RNA - pons [nTPM]":"2.5","Tissue RNA - prostate [nTPM]":"3.5","Tissue RNA - rectum [nTPM]":"3.6","Tissue RNA - retina [nTPM]":"3.3","Tissue RNA - salivary gland [nTPM]":"2.9","Tissue RNA - seminal vesicle [nTPM]":"3.3","Tissue RNA - skeletal muscle [nTPM]":"5.1","Tissue RNA - skin 1 [nTPM]":"4.6","Tissue RNA - small intestine [nTPM]":"2.6","Tissue RNA - smooth muscle [nTPM]":"3.6","Tissue RNA - spinal cord [nTPM]":"2.2","Tissue RNA - spleen [nTPM]":"4.6","Tissue RNA - stomach 1 [nTPM]":"3.3","Tissue RNA - testis [nTPM]":"2.8","Tissue RNA - thalamus [nTPM]":"2.3","Tissue RNA - thymus [nTPM]":"4.6","Tissue RNA - thyroid gland [nTPM]":"5.2","Tissue RNA - tongue [nTPM]":"4.7","Tissue RNA - tonsil [nTPM]":"5.9","Tissue RNA - urinary bladder [nTPM]":"3.5","Tissue RNA - vagina [nTPM]":"2.8","Tissue RNA - white matter [nTPM]":"2.3","Cell RNA - A-431 [nTPM]":"5.4","Cell RNA - A549 [nTPM]":"6.5","Cell RNA - AF22 [nTPM]":"6.6","Cell RNA - AN3-CA [nTPM]":"7.2","Cell RNA - ASC diff [nTPM]":"3.6","Cell RNA - ASC TERT1 [nTPM]":"7.9","Cell RNA - BEWO [nTPM]":"5.4","Cell RNA - BJ [nTPM]":"10.2","Cell RNA - BJ hTERT+ [nTPM]":"7.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.0","Cell RNA - CACO-2 [nTPM]":"12.1","Cell RNA - CAPAN-2 [nTPM]":"9.7","Cell RNA - Daudi [nTPM]":"12.6","Cell RNA - EFO-21 [nTPM]":"5.8","Cell RNA - fHDF\/TERT166 [nTPM]":"10.0","Cell RNA - GAMG [nTPM]":"10.2","Cell RNA - HaCaT [nTPM]":"9.6","Cell RNA - HAP1 [nTPM]":"9.9","Cell RNA - HBEC3-KT [nTPM]":"8.5","Cell RNA - HBF TERT88 [nTPM]":"9.6","Cell RNA - HDLM-2 [nTPM]":"11.4","Cell RNA - HEK 293 [nTPM]":"6.6","Cell RNA - HEL [nTPM]":"10.6","Cell RNA - HeLa [nTPM]":"2.5","Cell RNA - Hep G2 [nTPM]":"5.6","Cell RNA - HHSteC [nTPM]":"5.3","Cell RNA - HL-60 [nTPM]":"13.7","Cell RNA - HMC-1 [nTPM]":"12.6","Cell RNA - HSkMC [nTPM]":"4.9","Cell RNA - hTCEpi [nTPM]":"9.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.5","Cell RNA - hTERT-HME1 [nTPM]":"12.0","Cell RNA - hTERT-RPE1 [nTPM]":"3.8","Cell RNA - HUVEC TERT2 [nTPM]":"9.3","Cell RNA - JURKAT [nTPM]":"9.9","Cell RNA - K-562 [nTPM]":"15.2","Cell RNA - Karpas-707 [nTPM]":"4.1","Cell RNA - LHCN-M2 [nTPM]":"5.9","Cell RNA - MCF7 [nTPM]":"4.9","Cell RNA - MOLT-4 [nTPM]":"12.4","Cell RNA - NB-4 [nTPM]":"6.8","Cell RNA - NTERA-2 [nTPM]":"8.7","Cell RNA - OE19 [nTPM]":"10.5","Cell RNA - PC-3 [nTPM]":"10.6","Cell RNA - REH [nTPM]":"11.1","Cell RNA - RH-30 [nTPM]":"10.2","Cell RNA - RPMI-8226 [nTPM]":"8.7","Cell RNA - RPTEC TERT1 [nTPM]":"5.9","Cell RNA - RT4 [nTPM]":"5.8","Cell RNA - SCLC-21H [nTPM]":"6.0","Cell RNA - SH-SY5Y [nTPM]":"6.7","Cell RNA - SiHa [nTPM]":"5.9","Cell RNA - SK-BR-3 [nTPM]":"4.4","Cell RNA - SK-MEL-30 [nTPM]":"4.5","Cell RNA - SuSa [nTPM]":"4.0","Cell RNA - T-47d [nTPM]":"7.2","Cell RNA - THP-1 [nTPM]":"4.1","Cell RNA - TIME [nTPM]":"8.8","Cell RNA - U-138 MG [nTPM]":"16.1","Cell RNA - U-2 OS [nTPM]":"9.6","Cell RNA - U-2197 [nTPM]":"5.3","Cell RNA - U-251 MG [nTPM]":"12.9","Cell RNA - U-266\/70 [nTPM]":"3.8","Cell RNA - U-266\/84 [nTPM]":"4.3","Cell RNA - U-698 [nTPM]":"9.7","Cell RNA - U-87 MG [nTPM]":"4.5","Cell RNA - U-937 [nTPM]":"9.0","Cell RNA - WM-115 [nTPM]":"16.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"2.2","Blood RNA - intermediate monocyte [nTPM]":"2.1","Blood RNA - MAIT T-cell [nTPM]":"2.1","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.6","Blood RNA - memory CD8 T-cell [nTPM]":"1.9","Blood RNA - myeloid DC [nTPM]":"1.7","Blood RNA - naive B-cell [nTPM]":"1.9","Blood RNA - naive CD4 T-cell [nTPM]":"3.0","Blood RNA - naive CD8 T-cell [nTPM]":"2.6","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"2.8","Blood RNA - non-classical monocyte [nTPM]":"1.5","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"1.8","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"2.4","Brain RNA - basal ganglia [nTPM]":"3.0","Brain RNA - cerebellum [nTPM]":"2.6","Brain RNA - cerebral cortex [nTPM]":"2.8","Brain RNA - hippocampal formation [nTPM]":"2.4","Brain RNA - hypothalamus [nTPM]":"2.6","Brain RNA - medulla oblongata [nTPM]":"2.2","Brain RNA - midbrain [nTPM]":"2.6","Brain RNA - pons [nTPM]":"2.5","Brain RNA - spinal cord [nTPM]":"2.2","Brain RNA - thalamus [nTPM]":"2.3","Brain RNA - white matter [nTPM]":"2.3","Single Cell Type RNA - Adipocytes [nTPM]":"4.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.3","Single Cell Type RNA - Astrocytes [nTPM]":"4.6","Single Cell Type RNA - B-cells [nTPM]":"8.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"5.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"3.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.3","Single Cell Type RNA - dendritic cells [nTPM]":"3.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.6","Single Cell Type RNA - Endothelial cells [nTPM]":"4.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"4.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.7","Single Cell Type RNA - Fibroblasts [nTPM]":"4.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.3","Single Cell Type RNA - granulocytes [nTPM]":"10.1","Single Cell Type RNA - Granulosa cells [nTPM]":"5.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.9","Single Cell Type RNA - Hepatocytes [nTPM]":"6.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.8","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"27.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.8","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.8","Single Cell Type RNA - Langerhans cells [nTPM]":"2.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"4.1","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"4.7","Single Cell Type RNA - Muller glia cells [nTPM]":"3.0","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"23.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.7","Single Cell Type RNA - Paneth cells [nTPM]":"5.2","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"3.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.0","Single Cell Type RNA - Spermatocytes [nTPM]":"1.8","Single Cell Type RNA - Spermatogonia [nTPM]":"3.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"6.6","Single Cell Type RNA - Theca cells [nTPM]":"5.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"ALOX12","Gene synonym":["12S-LOX"],"Ensembl":"ENSG00000108839","Gene description":"Arachidonate 12-lipoxygenase, 12S type","Uniprot":["P18054"],"Chromosome":"17","Position":"6996049-7010754","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Dioxygenase","Hydrolase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"34.6","esophagus":"49.4","vagina":"105.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Macrophages":"17.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"4.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"A-431":"25.5","HEL":"40.4"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"olfactory bulb":"4.4"},"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010691","CAB019287","HPA064819"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"49000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 51: Myeloid cells - Hemostasis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nuclear speckles","Vesicles"],"Antibody RRID":{"CAB019287":null,"HPA010691":"AB_1844756","HPA064819":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.0","Tissue RNA - adrenal gland [nTPM]":"1.5","Tissue RNA - amygdala [nTPM]":"0.9","Tissue RNA - appendix [nTPM]":"3.2","Tissue RNA - basal ganglia [nTPM]":"1.5","Tissue RNA - bone marrow [nTPM]":"4.7","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"1.4","Tissue RNA - cervix [nTPM]":"34.6","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"1.8","Tissue RNA - endometrium 1 [nTPM]":"2.2","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"49.4","Tissue RNA - fallopian tube [nTPM]":"1.2","Tissue RNA - gallbladder [nTPM]":"3.1","Tissue RNA - heart muscle [nTPM]":"1.4","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"0.4","Tissue RNA - kidney [nTPM]":"0.5","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"1.1","Tissue RNA - lymph node [nTPM]":"3.9","Tissue RNA - medulla oblongata [nTPM]":"1.3","Tissue RNA - midbrain [nTPM]":"0.7","Tissue RNA - ovary [nTPM]":"1.3","Tissue RNA - pancreas [nTPM]":"1.9","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"1.1","Tissue RNA - pons [nTPM]":"1.0","Tissue RNA - prostate [nTPM]":"0.8","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"3.1","Tissue RNA - salivary gland [nTPM]":"20.2","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"1.6","Tissue RNA - skin 1 [nTPM]":"21.7","Tissue RNA - small intestine [nTPM]":"2.0","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"3.3","Tissue RNA - stomach 1 [nTPM]":"1.1","Tissue RNA - testis [nTPM]":"1.3","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"1.9","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"3.8","Tissue RNA - urinary bladder [nTPM]":"1.5","Tissue RNA - vagina [nTPM]":"105.7","Tissue RNA - white matter [nTPM]":"3.4","Cell RNA - A-431 [nTPM]":"25.5","Cell RNA - A549 [nTPM]":"4.2","Cell RNA - AF22 [nTPM]":"1.9","Cell RNA - AN3-CA [nTPM]":"1.4","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"1.7","Cell RNA - BJ [nTPM]":"1.6","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"3.7","Cell RNA - CAPAN-2 [nTPM]":"0.9","Cell RNA - Daudi [nTPM]":"1.3","Cell RNA - EFO-21 [nTPM]":"0.9","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"1.4","Cell RNA - HaCaT [nTPM]":"3.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"2.8","Cell RNA - HEK 293 [nTPM]":"3.2","Cell RNA - HEL [nTPM]":"40.4","Cell RNA - HeLa [nTPM]":"6.8","Cell RNA - Hep G2 [nTPM]":"2.8","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"6.5","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"2.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"2.8","Cell RNA - K-562 [nTPM]":"2.7","Cell RNA - Karpas-707 [nTPM]":"1.4","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"0.9","Cell RNA - NTERA-2 [nTPM]":"1.3","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.8","Cell RNA - REH [nTPM]":"1.4","Cell RNA - RH-30 [nTPM]":"0.8","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"3.2","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.9","Cell RNA - SiHa [nTPM]":"0.7","Cell RNA - SK-BR-3 [nTPM]":"0.8","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"2.4","Cell RNA - T-47d [nTPM]":"1.5","Cell RNA - THP-1 [nTPM]":"1.1","Cell RNA - TIME [nTPM]":"4.6","Cell RNA - U-138 MG [nTPM]":"2.2","Cell RNA - U-2 OS [nTPM]":"1.2","Cell RNA - U-2197 [nTPM]":"2.1","Cell RNA - U-251 MG [nTPM]":"1.1","Cell RNA - U-266\/70 [nTPM]":"0.8","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.7","Cell RNA - U-87 MG [nTPM]":"1.2","Cell RNA - U-937 [nTPM]":"3.0","Cell RNA - WM-115 [nTPM]":"1.0","Blood RNA - basophil [nTPM]":"2.1","Blood RNA - classical monocyte [nTPM]":"0.9","Blood RNA - eosinophil [nTPM]":"1.8","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"1.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"4.5","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"13.6","Brain RNA - amygdala [nTPM]":"0.9","Brain RNA - basal ganglia [nTPM]":"1.5","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"1.4","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"0.4","Brain RNA - medulla oblongata [nTPM]":"1.3","Brain RNA - midbrain [nTPM]":"0.7","Brain RNA - pons [nTPM]":"1.0","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"3.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"17.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"2.0"},{"Gene":"ALOX15","Gene synonym":["15-LOX-1"],"Ensembl":"ENSG00000161905","Gene description":"Arachidonate 15-lipoxygenase","Uniprot":["P16050"],"Chromosome":"17","Position":"4630919-4642294","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Dioxygenase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"37.2","fallopian tube":"12.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Club cells":"60.3","Langerhans cells":"72.2","Respiratory ciliated cells":"191.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"cervical cancer":"6.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"193","RNA blood cell specific nTPM":{"eosinophil":"602.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"193","RNA blood lineage specific nTPM":{"granulocytes":"602.9"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"HMC-1":"15.9","MCF7":"14.7","T-47d":"4.2"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004962","CAB004963","HPA013859"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB004962":null,"CAB004963":null,"HPA013859":"AB_1844758"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Tissue RNA - adipose tissue [nTPM]":"37.2","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.6","Tissue RNA - appendix [nTPM]":"1.6","Tissue RNA - basal ganglia [nTPM]":"2.0","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"3.2","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"1.3","Tissue RNA - cervix [nTPM]":"0.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.6","Tissue RNA - duodenum [nTPM]":"1.9","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"0.8","Tissue RNA - fallopian tube [nTPM]":"12.7","Tissue RNA - gallbladder [nTPM]":"0.6","Tissue RNA - heart muscle [nTPM]":"2.9","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.5","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"6.6","Tissue RNA - lymph node [nTPM]":"1.9","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"3.0","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"1.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"2.2","Tissue RNA - small intestine [nTPM]":"3.3","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"1.4","Tissue RNA - stomach 1 [nTPM]":"1.0","Tissue RNA - testis [nTPM]":"1.8","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.6","Tissue RNA - urinary bladder [nTPM]":"1.1","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"1.7","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.6","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"15.9","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"1.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"14.7","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"1.1","Cell RNA - OE19 [nTPM]":"1.3","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"1.2","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"4.2","Cell RNA - THP-1 [nTPM]":"0.6","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"602.9","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"3.1","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"2.7","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"0.6","Brain RNA - basal ganglia [nTPM]":"2.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"1.3","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.5","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"60.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.8","Single Cell Type RNA - dendritic cells [nTPM]":"1.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"19.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"3.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"72.2","Single Cell Type RNA - Late spermatids [nTPM]":"2.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"3.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"191.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.9","Single Cell Type RNA - Spermatocytes [nTPM]":"1.2","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.4","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"ALOXE3","Gene synonym":["E-LOX","eLOX3"],"Ensembl":"ENSG00000179148","Gene description":"Arachidonate lipoxygenase 3","Uniprot":["Q9BYJ1"],"Chromosome":"17","Position":"8095900-8119047","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Dioxygenase","Isomerase","Lyase","Oxidoreductase"],"Disease involvement":["Disease variant","Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"27","RNA tissue specific nTPM":{"skin 1":"56.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"2.1","Pancreatic endocrine cells":"6.3","Prostatic glandular cells":"1.8","Spermatocytes":"1.8","Spermatogonia":"1.7","Suprabasal keratinocytes":"1.8"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"cervical cancer":"1.1","head and neck cancer":"3.9","melanoma":"1.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"6.4","HBEC3-KT":"10.1","hTCEpi":"7.3","hTERT-HME1":"13.7","T-47d":"4.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023120","HPA078597"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 16: Pancreatic endocrine cells - Mixed function","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA023120":"AB_10959300","HPA078597":"AB_2732385"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.6","Tissue RNA - cerebellum [nTPM]":"1.9","Tissue RNA - cerebral cortex [nTPM]":"2.1","Tissue RNA - cervix [nTPM]":"0.6","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.7","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"0.4","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.8","Tissue RNA - midbrain [nTPM]":"0.7","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.7","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"56.2","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"1.2","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"1.8","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"6.4","Cell RNA - A549 [nTPM]":"0.7","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.4","Cell RNA - BJ hTERT+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.5","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"2.9","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"0.8","Cell RNA - HBEC3-KT [nTPM]":"10.1","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"7.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"13.7","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.9","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"2.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"2.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.7","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"4.4","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"2.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.8","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"1.9","Brain RNA - cerebral cortex [nTPM]":"2.1","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"0.4","Brain RNA - medulla oblongata [nTPM]":"0.8","Brain RNA - midbrain [nTPM]":"0.7","Brain RNA - pons [nTPM]":"0.7","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.2","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"1.8","Single Cell Type RNA - Spermatogonia [nTPM]":"1.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"ALPK3","Gene synonym":["KIAA1330","MAK","Midori"],"Ensembl":"ENSG00000136383","Gene description":"Alpha kinase 3","Uniprot":["Q96L96"],"Chromosome":"15","Position":"84817356-84873479","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Developmental protein","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cardiomyopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"heart muscle":"62.7","skeletal muscle":"195.8","tongue":"59.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"64.1","Exocrine glandular cells":"20.5","Skeletal myocytes":"51.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"14.3","HDLM-2":"10.7","HUVEC TERT2":"15.5","LHCN-M2":"21.2","NTERA-2":"12.9","RH-30":"37.7","THP-1":"9.6"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026558"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 37: Myocytes - Muscle contraction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA026558":"AB_1844774"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.95e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Tissue RNA - adipose tissue [nTPM]":"12.5","Tissue RNA - adrenal gland [nTPM]":"9.6","Tissue RNA - amygdala [nTPM]":"1.2","Tissue RNA - appendix [nTPM]":"0.9","Tissue RNA - basal ganglia [nTPM]":"1.6","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"4.4","Tissue RNA - cerebellum [nTPM]":"1.0","Tissue RNA - cerebral cortex [nTPM]":"2.2","Tissue RNA - cervix [nTPM]":"2.2","Tissue RNA - choroid plexus [nTPM]":"9.3","Tissue RNA - colon [nTPM]":"7.5","Tissue RNA - duodenum [nTPM]":"0.6","Tissue RNA - endometrium 1 [nTPM]":"1.5","Tissue RNA - epididymis [nTPM]":"5.4","Tissue RNA - esophagus [nTPM]":"3.0","Tissue RNA - fallopian tube [nTPM]":"1.7","Tissue RNA - gallbladder [nTPM]":"1.8","Tissue RNA - heart muscle [nTPM]":"62.7","Tissue RNA - hippocampal formation [nTPM]":"1.3","Tissue RNA - hypothalamus [nTPM]":"3.8","Tissue RNA - kidney [nTPM]":"13.5","Tissue RNA - liver [nTPM]":"5.9","Tissue RNA - lung [nTPM]":"5.5","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"2.2","Tissue RNA - midbrain [nTPM]":"3.4","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"7.7","Tissue RNA - parathyroid gland [nTPM]":"11.2","Tissue RNA - pituitary gland [nTPM]":"26.1","Tissue RNA - placenta [nTPM]":"2.5","Tissue RNA - pons [nTPM]":"4.5","Tissue RNA - prostate [nTPM]":"2.4","Tissue RNA - rectum [nTPM]":"0.8","Tissue RNA - retina [nTPM]":"2.5","Tissue RNA - salivary gland [nTPM]":"2.6","Tissue RNA - seminal vesicle [nTPM]":"1.3","Tissue RNA - skeletal muscle [nTPM]":"195.8","Tissue RNA - skin 1 [nTPM]":"1.0","Tissue RNA - small intestine [nTPM]":"2.1","Tissue RNA - smooth muscle [nTPM]":"3.1","Tissue RNA - spinal cord [nTPM]":"1.6","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"5.2","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"3.9","Tissue RNA - thymus [nTPM]":"0.6","Tissue RNA - thyroid gland [nTPM]":"3.6","Tissue RNA - tongue [nTPM]":"59.1","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"3.6","Tissue RNA - vagina [nTPM]":"1.4","Tissue RNA - white matter [nTPM]":"1.1","Cell RNA - A-431 [nTPM]":"1.8","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.3","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"14.3","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"6.3","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"1.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"10.7","Cell RNA - HEK 293 [nTPM]":"1.7","Cell RNA - HEL [nTPM]":"1.8","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"1.3","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"15.5","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"21.2","Cell RNA - MCF7 [nTPM]":"0.9","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"12.9","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"37.7","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"4.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"2.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"1.9","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"9.6","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.9","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.2","Brain RNA - basal ganglia [nTPM]":"1.6","Brain RNA - cerebellum [nTPM]":"1.0","Brain RNA - cerebral cortex [nTPM]":"2.2","Brain RNA - hippocampal formation [nTPM]":"1.3","Brain RNA - hypothalamus [nTPM]":"3.8","Brain RNA - medulla oblongata [nTPM]":"2.2","Brain RNA - midbrain [nTPM]":"3.4","Brain RNA - pons [nTPM]":"4.5","Brain RNA - spinal cord [nTPM]":"1.6","Brain RNA - thalamus [nTPM]":"3.9","Brain RNA - white matter [nTPM]":"1.1","Single Cell Type RNA - Adipocytes [nTPM]":"3.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.7","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"4.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"64.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"2.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.0","Single Cell Type RNA - Endothelial cells [nTPM]":"8.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.1","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"20.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"3.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.9","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"8.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"1.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"12.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"5.2","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"4.7","Single Cell Type RNA - Muller glia cells [nTPM]":"1.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.4","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"51.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"3.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"1.6"},{"Gene":"ALPL","Gene synonym":["HOPS","TNALP","TNAP","TNSALP"],"Ensembl":"ENSG00000162551","Gene description":"Alkaline phosphatase, biomineralization associated","Uniprot":["P05186"],"Chromosome":"1","Position":"21509397-21578410","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Biomineralization"],"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"60.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"92.0","Breast myoepithelial cells":"32.4","Glandular and luminal cells":"43.3","Hepatic stellate cells":"40.7","Hepatocytes":"30.1","Proximal tubular cells":"43.9","Rod photoreceptor cells":"34.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"199.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"90","RNA blood cell specific nTPM":{"neutrophil":"379.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"139","RNA blood lineage specific nTPM":{"granulocytes":"379.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HSkMC":"176.9","hTEC\/SVTERT24-B":"141.2","LHCN-M2":"103.7","NTERA-2":"41.2","SCLC-21H":"88.2","SuSa":"48.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007105","HPA008765","CAB020829"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"13000000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 11: Alveolar cells - Smell perception","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB020829":null,"HPA007105":"AB_1078137","HPA008765":"AB_1078138"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.57e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.08e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Tissue RNA - adipose tissue [nTPM]":"24.7","Tissue RNA - adrenal gland [nTPM]":"60.7","Tissue RNA - amygdala [nTPM]":"19.5","Tissue RNA - appendix [nTPM]":"27.9","Tissue RNA - basal ganglia [nTPM]":"16.7","Tissue RNA - bone marrow [nTPM]":"4.2","Tissue RNA - breast [nTPM]":"22.9","Tissue RNA - cerebellum [nTPM]":"18.0","Tissue RNA - cerebral cortex [nTPM]":"25.8","Tissue RNA - cervix [nTPM]":"3.4","Tissue RNA - choroid plexus [nTPM]":"26.0","Tissue RNA - colon [nTPM]":"5.0","Tissue RNA - duodenum [nTPM]":"2.6","Tissue RNA - endometrium 1 [nTPM]":"5.8","Tissue RNA - epididymis [nTPM]":"1.3","Tissue RNA - esophagus [nTPM]":"4.1","Tissue RNA - fallopian tube [nTPM]":"10.4","Tissue RNA - gallbladder [nTPM]":"3.9","Tissue RNA - heart muscle [nTPM]":"16.4","Tissue RNA - hippocampal formation [nTPM]":"17.8","Tissue RNA - hypothalamus [nTPM]":"18.8","Tissue RNA - kidney [nTPM]":"45.7","Tissue RNA - liver [nTPM]":"56.3","Tissue RNA - lung [nTPM]":"54.9","Tissue RNA - lymph node [nTPM]":"6.4","Tissue RNA - medulla oblongata [nTPM]":"21.7","Tissue RNA - midbrain [nTPM]":"17.7","Tissue RNA - ovary [nTPM]":"2.8","Tissue RNA - pancreas [nTPM]":"3.9","Tissue RNA - parathyroid gland [nTPM]":"3.3","Tissue RNA - pituitary gland [nTPM]":"9.3","Tissue RNA - placenta [nTPM]":"3.1","Tissue RNA - pons [nTPM]":"22.4","Tissue RNA - prostate [nTPM]":"7.1","Tissue RNA - rectum [nTPM]":"1.5","Tissue RNA - retina [nTPM]":"18.8","Tissue RNA - salivary gland [nTPM]":"6.4","Tissue RNA - seminal vesicle [nTPM]":"9.2","Tissue RNA - skeletal muscle [nTPM]":"1.1","Tissue RNA - skin 1 [nTPM]":"4.2","Tissue RNA - small intestine [nTPM]":"7.5","Tissue RNA - smooth muscle [nTPM]":"3.5","Tissue RNA - spinal cord [nTPM]":"18.2","Tissue RNA - spleen [nTPM]":"45.5","Tissue RNA - stomach 1 [nTPM]":"4.7","Tissue RNA - testis [nTPM]":"4.2","Tissue RNA - thalamus [nTPM]":"21.3","Tissue RNA - thymus [nTPM]":"1.5","Tissue RNA - thyroid gland [nTPM]":"8.6","Tissue RNA - tongue [nTPM]":"5.7","Tissue RNA - tonsil [nTPM]":"5.9","Tissue RNA - urinary bladder [nTPM]":"9.7","Tissue RNA - vagina [nTPM]":"3.3","Tissue RNA - white matter [nTPM]":"17.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"5.2","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.8","Cell RNA - ASC TERT1 [nTPM]":"6.6","Cell RNA - BEWO [nTPM]":"11.4","Cell RNA - BJ [nTPM]":"0.4","Cell RNA - BJ hTERT+ [nTPM]":"2.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.5","Cell RNA - CACO-2 [nTPM]":"1.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"2.4","Cell RNA - EFO-21 [nTPM]":"7.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"31.3","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.6","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"2.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"3.5","Cell RNA - Hep G2 [nTPM]":"3.9","Cell RNA - HHSteC [nTPM]":"1.8","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.7","Cell RNA - HSkMC [nTPM]":"176.9","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"141.2","Cell RNA - hTERT-HME1 [nTPM]":"0.5","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"103.7","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"41.2","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"3.8","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"88.2","Cell RNA - SH-SY5Y [nTPM]":"1.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"48.1","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"5.2","Cell RNA - U-2 OS [nTPM]":"4.3","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.9","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"4.2","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"2.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"379.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"19.5","Brain RNA - basal ganglia [nTPM]":"16.7","Brain RNA - cerebellum [nTPM]":"18.0","Brain RNA - cerebral cortex [nTPM]":"25.8","Brain RNA - hippocampal formation [nTPM]":"17.8","Brain RNA - hypothalamus [nTPM]":"18.8","Brain RNA - medulla oblongata [nTPM]":"21.7","Brain RNA - midbrain [nTPM]":"17.7","Brain RNA - pons [nTPM]":"22.4","Brain RNA - spinal cord [nTPM]":"18.2","Brain RNA - thalamus [nTPM]":"21.3","Brain RNA - white matter [nTPM]":"17.3","Single Cell Type RNA - Adipocytes [nTPM]":"25.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"92.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"3.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"2.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"32.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"17.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.2","Single Cell Type RNA - Endothelial cells [nTPM]":"26.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"6.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"43.3","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"10.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"40.7","Single Cell Type RNA - Hepatocytes [nTPM]":"30.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"8.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"6.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"43.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"34.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"14.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"8.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"AMACR","Gene synonym":["P504S","RACE"],"Ensembl":"ENSG00000242110","Gene description":"Alpha-methylacyl-CoA racemase","Uniprot":["Q9UHK6"],"Chromosome":"5","Position":"33986165-34008104","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Isomerase"],"Disease involvement":["Disease variant","Intrahepatic cholestasis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"134.3","liver":"180.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"19.7","Hepatocytes":"21.6","Late spermatids":"21.6","Proximal tubular cells":"38.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"liver cancer":"8.8","prostate cancer":"34.5","renal cancer":"14.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-266\/70":"175.4","U-266\/84":"98.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB001809","HPA019527","HPA020912"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"70000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB001809":"AB_2305454","HPA019527":"AB_10669651","HPA020912":"AB_10670034"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.11e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Tissue RNA - adipose tissue [nTPM]":"8.6","Tissue RNA - adrenal gland [nTPM]":"15.0","Tissue RNA - amygdala [nTPM]":"5.9","Tissue RNA - appendix [nTPM]":"5.0","Tissue RNA - basal ganglia [nTPM]":"5.5","Tissue RNA - bone marrow [nTPM]":"3.0","Tissue RNA - breast [nTPM]":"6.4","Tissue RNA - cerebellum [nTPM]":"4.6","Tissue RNA - cerebral cortex [nTPM]":"6.0","Tissue RNA - cervix [nTPM]":"6.5","Tissue RNA - choroid plexus [nTPM]":"4.6","Tissue RNA - colon [nTPM]":"40.0","Tissue RNA - duodenum [nTPM]":"18.0","Tissue RNA - endometrium 1 [nTPM]":"4.7","Tissue RNA - epididymis [nTPM]":"9.6","Tissue RNA - esophagus [nTPM]":"15.6","Tissue RNA - fallopian tube [nTPM]":"6.2","Tissue RNA - gallbladder [nTPM]":"20.5","Tissue RNA - heart muscle [nTPM]":"10.1","Tissue RNA - hippocampal formation [nTPM]":"5.4","Tissue RNA - hypothalamus [nTPM]":"7.8","Tissue RNA - kidney [nTPM]":"134.3","Tissue RNA - liver [nTPM]":"180.6","Tissue RNA - lung [nTPM]":"9.2","Tissue RNA - lymph node [nTPM]":"3.6","Tissue RNA - medulla oblongata [nTPM]":"5.9","Tissue RNA - midbrain [nTPM]":"6.4","Tissue RNA - ovary [nTPM]":"7.8","Tissue RNA - pancreas [nTPM]":"13.8","Tissue RNA - parathyroid gland [nTPM]":"13.0","Tissue RNA - pituitary gland [nTPM]":"5.7","Tissue RNA - placenta [nTPM]":"7.7","Tissue RNA - pons [nTPM]":"6.6","Tissue RNA - prostate [nTPM]":"39.3","Tissue RNA - rectum [nTPM]":"42.9","Tissue RNA - retina [nTPM]":"12.0","Tissue RNA - salivary gland [nTPM]":"60.7","Tissue RNA - seminal vesicle [nTPM]":"12.5","Tissue RNA - skeletal muscle [nTPM]":"19.2","Tissue RNA - skin 1 [nTPM]":"4.9","Tissue RNA - small intestine [nTPM]":"15.9","Tissue RNA - smooth muscle [nTPM]":"7.0","Tissue RNA - spinal cord [nTPM]":"5.8","Tissue RNA - spleen [nTPM]":"5.4","Tissue RNA - stomach 1 [nTPM]":"34.8","Tissue RNA - testis [nTPM]":"4.3","Tissue RNA - thalamus [nTPM]":"8.4","Tissue RNA - thymus [nTPM]":"4.8","Tissue RNA - thyroid gland [nTPM]":"8.3","Tissue RNA - tongue [nTPM]":"14.9","Tissue RNA - tonsil [nTPM]":"5.6","Tissue RNA - urinary bladder [nTPM]":"8.8","Tissue RNA - vagina [nTPM]":"8.5","Tissue RNA - white matter [nTPM]":"5.8","Cell RNA - A-431 [nTPM]":"12.7","Cell RNA - A549 [nTPM]":"20.2","Cell RNA - AF22 [nTPM]":"11.1","Cell RNA - AN3-CA [nTPM]":"14.3","Cell RNA - ASC diff [nTPM]":"7.7","Cell RNA - ASC TERT1 [nTPM]":"11.9","Cell RNA - BEWO [nTPM]":"19.1","Cell RNA - BJ [nTPM]":"16.6","Cell RNA - BJ hTERT+ [nTPM]":"12.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.7","Cell RNA - CACO-2 [nTPM]":"66.1","Cell RNA - CAPAN-2 [nTPM]":"15.1","Cell RNA - Daudi [nTPM]":"4.1","Cell RNA - EFO-21 [nTPM]":"8.7","Cell RNA - fHDF\/TERT166 [nTPM]":"23.6","Cell RNA - GAMG [nTPM]":"28.6","Cell RNA - HaCaT [nTPM]":"5.8","Cell RNA - HAP1 [nTPM]":"2.8","Cell RNA - HBEC3-KT [nTPM]":"12.0","Cell RNA - HBF TERT88 [nTPM]":"7.7","Cell RNA - HDLM-2 [nTPM]":"12.7","Cell RNA - HEK 293 [nTPM]":"10.9","Cell RNA - HEL [nTPM]":"9.8","Cell RNA - HeLa [nTPM]":"13.7","Cell RNA - Hep G2 [nTPM]":"19.0","Cell RNA - HHSteC [nTPM]":"5.4","Cell RNA - HL-60 [nTPM]":"6.0","Cell RNA - HMC-1 [nTPM]":"3.0","Cell RNA - HSkMC [nTPM]":"18.1","Cell RNA - hTCEpi [nTPM]":"6.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.7","Cell RNA - hTERT-HME1 [nTPM]":"3.6","Cell RNA - hTERT-RPE1 [nTPM]":"10.7","Cell RNA - HUVEC TERT2 [nTPM]":"8.5","Cell RNA - JURKAT [nTPM]":"8.3","Cell RNA - K-562 [nTPM]":"3.8","Cell RNA - Karpas-707 [nTPM]":"14.7","Cell RNA - LHCN-M2 [nTPM]":"22.4","Cell RNA - MCF7 [nTPM]":"9.6","Cell RNA - MOLT-4 [nTPM]":"5.0","Cell RNA - NB-4 [nTPM]":"7.6","Cell RNA - NTERA-2 [nTPM]":"10.0","Cell RNA - OE19 [nTPM]":"9.4","Cell RNA - PC-3 [nTPM]":"32.9","Cell RNA - REH [nTPM]":"6.0","Cell RNA - RH-30 [nTPM]":"18.6","Cell RNA - RPMI-8226 [nTPM]":"6.5","Cell RNA - RPTEC TERT1 [nTPM]":"33.2","Cell RNA - RT4 [nTPM]":"62.4","Cell RNA - SCLC-21H [nTPM]":"6.1","Cell RNA - SH-SY5Y [nTPM]":"8.7","Cell RNA - SiHa [nTPM]":"27.6","Cell RNA - SK-BR-3 [nTPM]":"19.3","Cell RNA - SK-MEL-30 [nTPM]":"16.9","Cell RNA - SuSa [nTPM]":"9.1","Cell RNA - T-47d [nTPM]":"14.9","Cell RNA - THP-1 [nTPM]":"5.9","Cell RNA - TIME [nTPM]":"15.6","Cell RNA - U-138 MG [nTPM]":"24.6","Cell RNA - U-2 OS [nTPM]":"5.4","Cell RNA - U-2197 [nTPM]":"6.2","Cell RNA - U-251 MG [nTPM]":"13.6","Cell RNA - U-266\/70 [nTPM]":"175.4","Cell RNA - U-266\/84 [nTPM]":"98.0","Cell RNA - U-698 [nTPM]":"7.4","Cell RNA - U-87 MG [nTPM]":"7.0","Cell RNA - U-937 [nTPM]":"12.1","Cell RNA - WM-115 [nTPM]":"18.8","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"6.0","Blood RNA - eosinophil [nTPM]":"9.3","Blood RNA - gdT-cell [nTPM]":"8.3","Blood RNA - intermediate monocyte [nTPM]":"8.0","Blood RNA - MAIT T-cell [nTPM]":"7.0","Blood RNA - memory B-cell [nTPM]":"7.1","Blood RNA - memory CD4 T-cell [nTPM]":"7.2","Blood RNA - memory CD8 T-cell [nTPM]":"6.4","Blood RNA - myeloid DC [nTPM]":"8.9","Blood RNA - naive B-cell [nTPM]":"5.2","Blood RNA - naive CD4 T-cell [nTPM]":"6.6","Blood RNA - naive CD8 T-cell [nTPM]":"4.8","Blood RNA - neutrophil [nTPM]":"10.0","Blood RNA - NK-cell [nTPM]":"8.7","Blood RNA - non-classical monocyte [nTPM]":"14.2","Blood RNA - plasmacytoid DC [nTPM]":"4.6","Blood RNA - T-reg [nTPM]":"7.9","Blood RNA - total PBMC [nTPM]":"6.0","Brain RNA - amygdala [nTPM]":"5.9","Brain RNA - basal ganglia [nTPM]":"5.5","Brain RNA - cerebellum [nTPM]":"4.6","Brain RNA - cerebral cortex [nTPM]":"6.0","Brain RNA - hippocampal formation [nTPM]":"5.4","Brain RNA - hypothalamus [nTPM]":"7.8","Brain RNA - medulla oblongata [nTPM]":"5.9","Brain RNA - midbrain [nTPM]":"6.4","Brain RNA - pons [nTPM]":"6.6","Brain RNA - spinal cord [nTPM]":"5.8","Brain RNA - thalamus [nTPM]":"8.4","Brain RNA - white matter [nTPM]":"5.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"4.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"3.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - dendritic cells [nTPM]":"2.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"19.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"8.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.2","Single Cell Type RNA - Endothelial cells [nTPM]":"3.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"21.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.1","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.1","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.9","Single Cell Type RNA - Langerhans cells [nTPM]":"0.2","Single Cell Type RNA - Late spermatids [nTPM]":"21.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"1.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.5","Single Cell Type RNA - Muller glia cells [nTPM]":"9.3","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.6","Single Cell Type RNA - Paneth cells [nTPM]":"4.5","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"1.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"38.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"1.5","Single Cell Type RNA - Theca cells [nTPM]":"1.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.4","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"AMHR2","Gene synonym":["MISR2","MISRII"],"Ensembl":"ENSG00000135409","Gene description":"Anti-Mullerian hormone receptor type 2","Uniprot":["Q16671"],"Chromosome":"12","Position":"53423855-53431672","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Pseudohermaphroditism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"41.5","ovary":"33.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"granulocytes":"26.0","Granulosa cells":"36.1","Theca cells":"94.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"0.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"19","RNA cell line specific nTPM":{"HEL":"40.1","K-562":"22.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"11","RNA pig brain regional specific nTPM":{"hippocampal formation":"9.4"},"Antibody":["HPA060228","HPA069636"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 51: Non-specific - Unknown function","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA060228":"AB_2684227","HPA069636":"AB_2686163"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.6","Tissue RNA - adrenal gland [nTPM]":"41.5","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.9","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"33.1","Tissue RNA - pancreas [nTPM]":"12.5","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"4.2","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"5.7","Tissue RNA - stomach 1 [nTPM]":"0.7","Tissue RNA - testis [nTPM]":"9.1","Tissue RNA - thalamus [nTPM]":"0.5","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"1.8","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.5","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"1.2","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.6","Cell RNA - HEL [nTPM]":"40.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.8","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.3","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"22.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.7","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.5","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.5","Single Cell Type RNA - Early spermatids [nTPM]":"2.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"4.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"2.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"26.0","Single Cell Type RNA - Granulosa cells [nTPM]":"36.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.2","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.5","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"94.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"AMPD1","Gene synonym":["MAD","MADA"],"Ensembl":"ENSG00000116748","Gene description":"Adenosine monophosphate deaminase 1","Uniprot":["P23109"],"Chromosome":"1","Position":"114673090-114695618","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Nucleotide metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"23","RNA tissue specific nTPM":{"skeletal muscle":"559.2","tongue":"211.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Plasma cells":"43.8","Skeletal myocytes":"13.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"0.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"29","RNA cell line specific nTPM":{"U-266\/70":"8.7"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026478","HPA028080"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"38000","Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 37: Myocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026478":"AB_10599969","HPA028080":"AB_10600776"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.75e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"3.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"5.6","Tissue RNA - duodenum [nTPM]":"16.4","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"5.8","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.7","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"1.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"3.5","Tissue RNA - rectum [nTPM]":"5.5","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"4.4","Tissue RNA - seminal vesicle [nTPM]":"0.9","Tissue RNA - skeletal muscle [nTPM]":"559.2","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"7.5","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"1.6","Tissue RNA - stomach 1 [nTPM]":"3.7","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"211.4","Tissue RNA - tonsil [nTPM]":"2.9","Tissue RNA - urinary bladder [nTPM]":"0.5","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"8.7","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"4.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"43.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.7","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"AMPD2","Gene synonym":["SPG63"],"Ensembl":"ENSG00000116337","Gene description":"Adenosine monophosphate deaminase 2","Uniprot":["Q01433"],"Chromosome":"1","Position":"109616104-109632051","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Nucleotide metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"62.6","Horizontal cells":"52.2","Macrophages":"52.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"19.4","eosinophil":"19.2","intermediate monocyte":"40.7","myeloid DC":"18.9","neutrophil":"61.1","non-classical monocyte":"44.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"18.9","granulocytes":"61.1","monocytes":"44.6"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027137","HPA045760"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"230000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA027137":"AB_2672129","HPA045760":"AB_2679443"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.78e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.3","Tissue RNA - adrenal gland [nTPM]":"17.5","Tissue RNA - amygdala [nTPM]":"31.2","Tissue RNA - appendix [nTPM]":"12.0","Tissue RNA - basal ganglia [nTPM]":"41.6","Tissue RNA - bone marrow [nTPM]":"28.6","Tissue RNA - breast [nTPM]":"7.4","Tissue RNA - cerebellum [nTPM]":"22.9","Tissue RNA - cerebral cortex [nTPM]":"34.7","Tissue RNA - cervix [nTPM]":"13.1","Tissue RNA - choroid plexus [nTPM]":"36.6","Tissue RNA - colon [nTPM]":"7.5","Tissue RNA - duodenum [nTPM]":"10.7","Tissue RNA - endometrium 1 [nTPM]":"11.5","Tissue RNA - epididymis [nTPM]":"4.1","Tissue RNA - esophagus [nTPM]":"7.2","Tissue RNA - fallopian tube [nTPM]":"13.1","Tissue RNA - gallbladder [nTPM]":"8.8","Tissue RNA - heart muscle [nTPM]":"7.2","Tissue RNA - hippocampal formation [nTPM]":"34.8","Tissue RNA - hypothalamus [nTPM]":"37.0","Tissue RNA - kidney [nTPM]":"10.5","Tissue RNA - liver [nTPM]":"16.2","Tissue RNA - lung [nTPM]":"13.4","Tissue RNA - lymph node [nTPM]":"7.6","Tissue RNA - medulla oblongata [nTPM]":"34.7","Tissue RNA - midbrain [nTPM]":"31.7","Tissue RNA - ovary [nTPM]":"17.5","Tissue RNA - pancreas [nTPM]":"10.0","Tissue RNA - parathyroid gland [nTPM]":"9.4","Tissue RNA - pituitary gland [nTPM]":"45.8","Tissue RNA - placenta [nTPM]":"7.6","Tissue RNA - pons [nTPM]":"33.6","Tissue RNA - prostate [nTPM]":"10.8","Tissue RNA - rectum [nTPM]":"4.1","Tissue RNA - retina [nTPM]":"10.5","Tissue RNA - salivary gland [nTPM]":"9.2","Tissue RNA - seminal vesicle [nTPM]":"12.0","Tissue RNA - skeletal muscle [nTPM]":"3.3","Tissue RNA - skin 1 [nTPM]":"8.5","Tissue RNA - small intestine [nTPM]":"10.8","Tissue RNA - smooth muscle [nTPM]":"7.1","Tissue RNA - spinal cord [nTPM]":"27.9","Tissue RNA - spleen [nTPM]":"19.0","Tissue RNA - stomach 1 [nTPM]":"8.6","Tissue RNA - testis [nTPM]":"4.3","Tissue RNA - thalamus [nTPM]":"39.3","Tissue RNA - thymus [nTPM]":"4.9","Tissue RNA - thyroid gland [nTPM]":"10.6","Tissue RNA - tongue [nTPM]":"1.5","Tissue RNA - tonsil [nTPM]":"5.9","Tissue RNA - urinary bladder [nTPM]":"7.5","Tissue RNA - vagina [nTPM]":"11.4","Tissue RNA - white matter [nTPM]":"29.0","Cell RNA - A-431 [nTPM]":"20.6","Cell RNA - A549 [nTPM]":"22.5","Cell RNA - AF22 [nTPM]":"20.5","Cell RNA - AN3-CA [nTPM]":"20.1","Cell RNA - ASC diff [nTPM]":"18.0","Cell RNA - ASC TERT1 [nTPM]":"18.7","Cell RNA - BEWO [nTPM]":"8.6","Cell RNA - BJ [nTPM]":"25.6","Cell RNA - BJ hTERT+ [nTPM]":"57.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"25.0","Cell RNA - CACO-2 [nTPM]":"19.1","Cell RNA - CAPAN-2 [nTPM]":"7.0","Cell RNA - Daudi [nTPM]":"10.5","Cell RNA - EFO-21 [nTPM]":"21.8","Cell RNA - fHDF\/TERT166 [nTPM]":"39.1","Cell RNA - GAMG [nTPM]":"16.0","Cell RNA - HaCaT [nTPM]":"11.3","Cell RNA - HAP1 [nTPM]":"15.8","Cell RNA - HBEC3-KT [nTPM]":"20.0","Cell RNA - HBF TERT88 [nTPM]":"13.4","Cell RNA - HDLM-2 [nTPM]":"13.0","Cell RNA - HEK 293 [nTPM]":"20.7","Cell RNA - HEL [nTPM]":"46.0","Cell RNA - HeLa [nTPM]":"15.6","Cell RNA - Hep G2 [nTPM]":"19.3","Cell RNA - HHSteC [nTPM]":"24.9","Cell RNA - HL-60 [nTPM]":"15.7","Cell RNA - HMC-1 [nTPM]":"45.7","Cell RNA - HSkMC [nTPM]":"23.3","Cell RNA - hTCEpi [nTPM]":"13.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.5","Cell RNA - hTERT-HME1 [nTPM]":"24.1","Cell RNA - hTERT-RPE1 [nTPM]":"28.2","Cell RNA - HUVEC TERT2 [nTPM]":"26.7","Cell RNA - JURKAT [nTPM]":"17.0","Cell RNA - K-562 [nTPM]":"17.4","Cell RNA - Karpas-707 [nTPM]":"13.0","Cell RNA - LHCN-M2 [nTPM]":"16.0","Cell RNA - MCF7 [nTPM]":"23.2","Cell RNA - MOLT-4 [nTPM]":"26.7","Cell RNA - NB-4 [nTPM]":"29.0","Cell RNA - NTERA-2 [nTPM]":"20.6","Cell RNA - OE19 [nTPM]":"17.1","Cell RNA - PC-3 [nTPM]":"22.9","Cell RNA - REH [nTPM]":"18.6","Cell RNA - RH-30 [nTPM]":"15.8","Cell RNA - RPMI-8226 [nTPM]":"17.3","Cell RNA - RPTEC TERT1 [nTPM]":"24.2","Cell RNA - RT4 [nTPM]":"8.7","Cell RNA - SCLC-21H [nTPM]":"19.3","Cell RNA - SH-SY5Y [nTPM]":"22.4","Cell RNA - SiHa [nTPM]":"17.4","Cell RNA - SK-BR-3 [nTPM]":"19.8","Cell RNA - SK-MEL-30 [nTPM]":"24.6","Cell RNA - SuSa [nTPM]":"5.7","Cell RNA - T-47d [nTPM]":"10.4","Cell RNA - THP-1 [nTPM]":"16.2","Cell RNA - TIME [nTPM]":"16.7","Cell RNA - U-138 MG [nTPM]":"27.7","Cell RNA - U-2 OS [nTPM]":"39.0","Cell RNA - U-2197 [nTPM]":"33.7","Cell RNA - U-251 MG [nTPM]":"25.4","Cell RNA - U-266\/70 [nTPM]":"48.4","Cell RNA - U-266\/84 [nTPM]":"28.4","Cell RNA - U-698 [nTPM]":"12.1","Cell RNA - U-87 MG [nTPM]":"50.8","Cell RNA - U-937 [nTPM]":"25.9","Cell RNA - WM-115 [nTPM]":"35.1","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"19.4","Blood RNA - eosinophil [nTPM]":"19.2","Blood RNA - gdT-cell [nTPM]":"5.3","Blood RNA - intermediate monocyte [nTPM]":"40.7","Blood RNA - MAIT T-cell [nTPM]":"8.0","Blood RNA - memory B-cell [nTPM]":"5.3","Blood RNA - memory CD4 T-cell [nTPM]":"5.2","Blood RNA - memory CD8 T-cell [nTPM]":"4.9","Blood RNA - myeloid DC [nTPM]":"18.9","Blood RNA - naive B-cell [nTPM]":"2.7","Blood RNA - naive CD4 T-cell [nTPM]":"6.4","Blood RNA - naive CD8 T-cell [nTPM]":"5.1","Blood RNA - neutrophil [nTPM]":"61.1","Blood RNA - NK-cell [nTPM]":"4.3","Blood RNA - non-classical monocyte [nTPM]":"44.6","Blood RNA - plasmacytoid DC [nTPM]":"2.6","Blood RNA - T-reg [nTPM]":"4.0","Blood RNA - total PBMC [nTPM]":"12.3","Brain RNA - amygdala [nTPM]":"31.2","Brain RNA - basal ganglia [nTPM]":"41.6","Brain RNA - cerebellum [nTPM]":"22.9","Brain RNA - cerebral cortex [nTPM]":"34.7","Brain RNA - hippocampal formation [nTPM]":"34.8","Brain RNA - hypothalamus [nTPM]":"37.0","Brain RNA - medulla oblongata [nTPM]":"34.7","Brain RNA - midbrain [nTPM]":"31.7","Brain RNA - pons [nTPM]":"33.6","Brain RNA - spinal cord [nTPM]":"27.9","Brain RNA - thalamus [nTPM]":"39.3","Brain RNA - white matter [nTPM]":"29.0","Single Cell Type RNA - Adipocytes [nTPM]":"3.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.5","Single Cell Type RNA - Astrocytes [nTPM]":"13.7","Single Cell Type RNA - B-cells [nTPM]":"9.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"41.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"5.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"62.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.9","Single Cell Type RNA - dendritic cells [nTPM]":"10.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.8","Single Cell Type RNA - Early spermatids [nTPM]":"3.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.4","Single Cell Type RNA - Endothelial cells [nTPM]":"7.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.5","Single Cell Type RNA - Erythroid cells [nTPM]":"5.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.6","Single Cell Type RNA - Fibroblasts [nTPM]":"12.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.5","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"11.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"20.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.8","Single Cell Type RNA - Horizontal cells [nTPM]":"52.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.6","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"42.1","Single Cell Type RNA - Langerhans cells [nTPM]":"42.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"13.1","Single Cell Type RNA - Macrophages [nTPM]":"52.5","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"16.1","Single Cell Type RNA - Muller glia cells [nTPM]":"10.5","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.3","Single Cell Type RNA - Paneth cells [nTPM]":"3.0","Single Cell Type RNA - Peritubular cells [nTPM]":"21.4","Single Cell Type RNA - Plasma cells [nTPM]":"11.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.6","Single Cell Type RNA - Spermatocytes [nTPM]":"4.2","Single Cell Type RNA - Spermatogonia [nTPM]":"3.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.6","Single Cell Type RNA - T-cells [nTPM]":"15.4","Single Cell Type RNA - Theca cells [nTPM]":"8.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.7","Single Cell Type RNA - Urothelial cells [nTPM]":"4.0"},{"Gene":"AMPD3","Gene synonym":[],"Ensembl":"ENSG00000133805","Gene description":"Adenosine monophosphate deaminase 3","Uniprot":["Q01432"],"Chromosome":"11","Position":"10308313-10507579","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Nucleotide metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"62.9","skeletal muscle":"73.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"111.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+":"44.2","CAPAN-2":"34.6","HMC-1":"36.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038662","HPA047408"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"77000","Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA038662":"AB_2676136","HPA047408":"AB_2680034"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.37e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.2","Tissue RNA - adrenal gland [nTPM]":"19.6","Tissue RNA - amygdala [nTPM]":"10.8","Tissue RNA - appendix [nTPM]":"20.7","Tissue RNA - basal ganglia [nTPM]":"22.5","Tissue RNA - bone marrow [nTPM]":"62.9","Tissue RNA - breast [nTPM]":"3.0","Tissue RNA - cerebellum [nTPM]":"19.1","Tissue RNA - cerebral cortex [nTPM]":"15.3","Tissue RNA - cervix [nTPM]":"6.0","Tissue RNA - choroid plexus [nTPM]":"10.8","Tissue RNA - colon [nTPM]":"4.9","Tissue RNA - duodenum [nTPM]":"6.5","Tissue RNA - endometrium 1 [nTPM]":"4.2","Tissue RNA - epididymis [nTPM]":"4.0","Tissue RNA - esophagus [nTPM]":"7.6","Tissue RNA - fallopian tube [nTPM]":"11.1","Tissue RNA - gallbladder [nTPM]":"6.4","Tissue RNA - heart muscle [nTPM]":"2.9","Tissue RNA - hippocampal formation [nTPM]":"10.4","Tissue RNA - hypothalamus [nTPM]":"15.9","Tissue RNA - kidney [nTPM]":"7.8","Tissue RNA - liver [nTPM]":"1.8","Tissue RNA - lung [nTPM]":"6.9","Tissue RNA - lymph node [nTPM]":"17.6","Tissue RNA - medulla oblongata [nTPM]":"21.1","Tissue RNA - midbrain [nTPM]":"20.5","Tissue RNA - ovary [nTPM]":"2.6","Tissue RNA - pancreas [nTPM]":"3.3","Tissue RNA - parathyroid gland [nTPM]":"24.1","Tissue RNA - pituitary gland [nTPM]":"18.2","Tissue RNA - placenta [nTPM]":"4.1","Tissue RNA - pons [nTPM]":"20.5","Tissue RNA - prostate [nTPM]":"7.4","Tissue RNA - rectum [nTPM]":"6.6","Tissue RNA - retina [nTPM]":"7.5","Tissue RNA - salivary gland [nTPM]":"6.4","Tissue RNA - seminal vesicle [nTPM]":"3.5","Tissue RNA - skeletal muscle [nTPM]":"73.3","Tissue RNA - skin 1 [nTPM]":"15.6","Tissue RNA - small intestine [nTPM]":"7.8","Tissue RNA - smooth muscle [nTPM]":"4.4","Tissue RNA - spinal cord [nTPM]":"14.0","Tissue RNA - spleen [nTPM]":"12.1","Tissue RNA - stomach 1 [nTPM]":"6.7","Tissue RNA - testis [nTPM]":"1.8","Tissue RNA - thalamus [nTPM]":"21.4","Tissue RNA - thymus [nTPM]":"13.9","Tissue RNA - thyroid gland [nTPM]":"3.6","Tissue RNA - tongue [nTPM]":"9.3","Tissue RNA - tonsil [nTPM]":"20.3","Tissue RNA - urinary bladder [nTPM]":"9.7","Tissue RNA - vagina [nTPM]":"7.9","Tissue RNA - white matter [nTPM]":"30.2","Cell RNA - A-431 [nTPM]":"14.1","Cell RNA - A549 [nTPM]":"2.0","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"7.1","Cell RNA - ASC TERT1 [nTPM]":"5.0","Cell RNA - BEWO [nTPM]":"0.8","Cell RNA - BJ [nTPM]":"12.4","Cell RNA - BJ hTERT+ [nTPM]":"44.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.1","Cell RNA - CACO-2 [nTPM]":"6.9","Cell RNA - CAPAN-2 [nTPM]":"34.6","Cell RNA - Daudi [nTPM]":"5.1","Cell RNA - EFO-21 [nTPM]":"1.2","Cell RNA - fHDF\/TERT166 [nTPM]":"5.7","Cell RNA - GAMG [nTPM]":"11.9","Cell RNA - HaCaT [nTPM]":"8.6","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"11.8","Cell RNA - HBF TERT88 [nTPM]":"8.8","Cell RNA - HDLM-2 [nTPM]":"12.7","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"12.5","Cell RNA - HeLa [nTPM]":"1.8","Cell RNA - Hep G2 [nTPM]":"1.0","Cell RNA - HHSteC [nTPM]":"2.4","Cell RNA - HL-60 [nTPM]":"17.2","Cell RNA - HMC-1 [nTPM]":"36.0","Cell RNA - HSkMC [nTPM]":"18.5","Cell RNA - hTCEpi [nTPM]":"17.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.0","Cell RNA - hTERT-HME1 [nTPM]":"7.7","Cell RNA - hTERT-RPE1 [nTPM]":"7.5","Cell RNA - HUVEC TERT2 [nTPM]":"1.4","Cell RNA - JURKAT [nTPM]":"8.3","Cell RNA - K-562 [nTPM]":"19.4","Cell RNA - Karpas-707 [nTPM]":"5.3","Cell RNA - LHCN-M2 [nTPM]":"10.1","Cell RNA - MCF7 [nTPM]":"0.5","Cell RNA - MOLT-4 [nTPM]":"10.2","Cell RNA - NB-4 [nTPM]":"22.3","Cell RNA - NTERA-2 [nTPM]":"1.6","Cell RNA - OE19 [nTPM]":"1.1","Cell RNA - PC-3 [nTPM]":"12.2","Cell RNA - REH [nTPM]":"3.7","Cell RNA - RH-30 [nTPM]":"15.9","Cell RNA - RPMI-8226 [nTPM]":"18.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.6","Cell RNA - RT4 [nTPM]":"11.5","Cell RNA - SCLC-21H [nTPM]":"5.1","Cell RNA - SH-SY5Y [nTPM]":"2.6","Cell RNA - SiHa [nTPM]":"2.7","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"0.8","Cell RNA - SuSa [nTPM]":"1.0","Cell RNA - T-47d [nTPM]":"0.4","Cell RNA - THP-1 [nTPM]":"5.8","Cell RNA - TIME [nTPM]":"3.4","Cell RNA - U-138 MG [nTPM]":"13.7","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"9.6","Cell RNA - U-251 MG [nTPM]":"0.5","Cell RNA - U-266\/70 [nTPM]":"4.8","Cell RNA - U-266\/84 [nTPM]":"2.9","Cell RNA - U-698 [nTPM]":"5.5","Cell RNA - U-87 MG [nTPM]":"15.7","Cell RNA - U-937 [nTPM]":"16.9","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"9.5","Blood RNA - classical monocyte [nTPM]":"6.4","Blood RNA - eosinophil [nTPM]":"19.4","Blood RNA - gdT-cell [nTPM]":"2.2","Blood RNA - intermediate monocyte [nTPM]":"3.9","Blood RNA - MAIT T-cell [nTPM]":"5.4","Blood RNA - memory B-cell [nTPM]":"7.7","Blood RNA - memory CD4 T-cell [nTPM]":"3.3","Blood RNA - memory CD8 T-cell [nTPM]":"2.6","Blood RNA - myeloid DC [nTPM]":"4.2","Blood RNA - naive B-cell [nTPM]":"5.3","Blood RNA - naive CD4 T-cell [nTPM]":"3.6","Blood RNA - naive CD8 T-cell [nTPM]":"2.5","Blood RNA - neutrophil [nTPM]":"8.4","Blood RNA - NK-cell [nTPM]":"3.8","Blood RNA - non-classical monocyte [nTPM]":"1.7","Blood RNA - plasmacytoid DC [nTPM]":"2.7","Blood RNA - T-reg [nTPM]":"2.1","Blood RNA - total PBMC [nTPM]":"2.8","Brain RNA - amygdala [nTPM]":"10.8","Brain RNA - basal ganglia [nTPM]":"22.5","Brain RNA - cerebellum [nTPM]":"19.1","Brain RNA - cerebral cortex [nTPM]":"15.3","Brain RNA - hippocampal formation [nTPM]":"10.4","Brain RNA - hypothalamus [nTPM]":"15.9","Brain RNA - medulla oblongata [nTPM]":"21.1","Brain RNA - midbrain [nTPM]":"20.5","Brain RNA - pons [nTPM]":"20.5","Brain RNA - spinal cord [nTPM]":"14.0","Brain RNA - thalamus [nTPM]":"21.4","Brain RNA - white matter [nTPM]":"30.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.9","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"14.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"23.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"9.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.9","Single Cell Type RNA - dendritic cells [nTPM]":"1.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"2.9","Single Cell Type RNA - Early spermatids [nTPM]":"7.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.7","Single Cell Type RNA - Endothelial cells [nTPM]":"1.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.2","Single Cell Type RNA - Erythroid cells [nTPM]":"20.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.5","Single Cell Type RNA - Fibroblasts [nTPM]":"8.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.9","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.9","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"15.2","Single Cell Type RNA - Langerhans cells [nTPM]":"7.6","Single Cell Type RNA - Late spermatids [nTPM]":"20.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"18.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"28.1","Single Cell Type RNA - monocytes [nTPM]":"14.0","Single Cell Type RNA - Muller glia cells [nTPM]":"6.5","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"111.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.3","Single Cell Type RNA - Paneth cells [nTPM]":"3.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"26.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"24.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - T-cells [nTPM]":"6.6","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.2","Single Cell Type RNA - Urothelial cells [nTPM]":"16.8"},{"Gene":"AMT","Gene synonym":["GCST","NKH"],"Ensembl":"ENSG00000145020","Gene description":"Aminomethyltransferase","Uniprot":["P48728"],"Chromosome":"3","Position":"49416778-49422685","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Aminotransferase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"49.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"42.4","Proximal enterocytes":"33.3","Undifferentiated cells":"31.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"7.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"17.1","Hep G2":"47.5","NTERA-2":"8.0","SH-SY5Y":"14.9","SuSa":"9.0"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005566"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA005566":"AB_1844811"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.14e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.17e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.90e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-3"},"Tissue RNA - adipose tissue [nTPM]":"4.7","Tissue RNA - adrenal gland [nTPM]":"12.8","Tissue RNA - amygdala [nTPM]":"9.8","Tissue RNA - appendix [nTPM]":"1.2","Tissue RNA - basal ganglia [nTPM]":"10.3","Tissue RNA - bone marrow [nTPM]":"8.8","Tissue RNA - breast [nTPM]":"5.6","Tissue RNA - cerebellum [nTPM]":"10.7","Tissue RNA - cerebral cortex [nTPM]":"11.7","Tissue RNA - cervix [nTPM]":"11.8","Tissue RNA - choroid plexus [nTPM]":"13.1","Tissue RNA - colon [nTPM]":"12.2","Tissue RNA - duodenum [nTPM]":"13.8","Tissue RNA - endometrium 1 [nTPM]":"6.8","Tissue RNA - epididymis [nTPM]":"8.2","Tissue RNA - esophagus [nTPM]":"3.5","Tissue RNA - fallopian tube [nTPM]":"10.1","Tissue RNA - gallbladder [nTPM]":"5.8","Tissue RNA - heart muscle [nTPM]":"21.6","Tissue RNA - hippocampal formation [nTPM]":"9.4","Tissue RNA - hypothalamus [nTPM]":"9.6","Tissue RNA - kidney [nTPM]":"23.2","Tissue RNA - liver [nTPM]":"49.1","Tissue RNA - lung [nTPM]":"5.4","Tissue RNA - lymph node [nTPM]":"2.1","Tissue RNA - medulla oblongata [nTPM]":"9.8","Tissue RNA - midbrain [nTPM]":"10.2","Tissue RNA - ovary [nTPM]":"12.5","Tissue RNA - pancreas [nTPM]":"19.5","Tissue RNA - parathyroid gland [nTPM]":"14.2","Tissue RNA - pituitary gland [nTPM]":"11.9","Tissue RNA - placenta [nTPM]":"2.3","Tissue RNA - pons [nTPM]":"9.8","Tissue RNA - prostate [nTPM]":"11.3","Tissue RNA - rectum [nTPM]":"11.8","Tissue RNA - retina [nTPM]":"6.5","Tissue RNA - salivary gland [nTPM]":"10.6","Tissue RNA - seminal vesicle [nTPM]":"8.5","Tissue RNA - skeletal muscle [nTPM]":"3.1","Tissue RNA - skin 1 [nTPM]":"4.8","Tissue RNA - small intestine [nTPM]":"12.1","Tissue RNA - smooth muscle [nTPM]":"3.7","Tissue RNA - spinal cord [nTPM]":"9.9","Tissue RNA - spleen [nTPM]":"6.3","Tissue RNA - stomach 1 [nTPM]":"11.1","Tissue RNA - testis [nTPM]":"3.0","Tissue RNA - thalamus [nTPM]":"10.0","Tissue RNA - thymus [nTPM]":"3.8","Tissue RNA - thyroid gland [nTPM]":"5.8","Tissue RNA - tongue [nTPM]":"4.2","Tissue RNA - tonsil [nTPM]":"1.5","Tissue RNA - urinary bladder [nTPM]":"8.0","Tissue RNA - vagina [nTPM]":"6.4","Tissue RNA - white matter [nTPM]":"9.9","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.7","Cell RNA - AF22 [nTPM]":"1.4","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"0.6","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"17.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"0.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.7","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"47.5","Cell RNA - HHSteC [nTPM]":"1.8","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.6","Cell RNA - hTCEpi [nTPM]":"1.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.7","Cell RNA - hTERT-RPE1 [nTPM]":"1.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.6","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"8.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.5","Cell RNA - RPMI-8226 [nTPM]":"1.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.8","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"14.9","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"1.1","Cell RNA - SuSa [nTPM]":"9.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.6","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"1.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.1","Blood RNA - eosinophil [nTPM]":"3.2","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"1.7","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"4.2","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"7.9","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.3","Brain RNA - amygdala [nTPM]":"9.8","Brain RNA - basal ganglia [nTPM]":"10.3","Brain RNA - cerebellum [nTPM]":"10.7","Brain RNA - cerebral cortex [nTPM]":"11.7","Brain RNA - hippocampal formation [nTPM]":"9.4","Brain RNA - hypothalamus [nTPM]":"9.6","Brain RNA - medulla oblongata [nTPM]":"9.8","Brain RNA - midbrain [nTPM]":"10.2","Brain RNA - pons [nTPM]":"9.8","Brain RNA - spinal cord [nTPM]":"9.9","Brain RNA - thalamus [nTPM]":"10.0","Brain RNA - white matter [nTPM]":"9.9","Single Cell Type RNA - Adipocytes [nTPM]":"1.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.2","Single Cell Type RNA - Astrocytes [nTPM]":"11.4","Single Cell Type RNA - B-cells [nTPM]":"3.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"17.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"21.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"6.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.6","Single Cell Type RNA - dendritic cells [nTPM]":"1.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"2.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.6","Single Cell Type RNA - Endothelial cells [nTPM]":"3.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.7","Single Cell Type RNA - Erythroid cells [nTPM]":"8.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.8","Single Cell Type RNA - Fibroblasts [nTPM]":"4.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.0","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"2.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"42.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.0","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.4","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.8","Single Cell Type RNA - Langerhans cells [nTPM]":"2.9","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"10.5","Single Cell Type RNA - Macrophages [nTPM]":"2.6","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"1.8","Single Cell Type RNA - Muller glia cells [nTPM]":"26.0","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"18.9","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"1.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"33.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.9","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.3","Single Cell Type RNA - T-cells [nTPM]":"3.8","Single Cell Type RNA - Theca cells [nTPM]":"1.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"31.6","Single Cell Type RNA - Urothelial cells [nTPM]":"10.9"},{"Gene":"ANK1","Gene synonym":["ANK","SPH1"],"Ensembl":"ENSG00000029534","Gene description":"Ankyrin 1","Uniprot":["P16157"],"Chromosome":"8","Position":"41653220-41896762","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Elliptocytosis","Hereditary hemolytic anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"skeletal muscle":"993.4","tongue":"629.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"164.7","Cone photoreceptor cells":"87.6","Erythroid cells":"250.2","Inhibitory neurons":"176.8","Skeletal myocytes":"51.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"memory B-cell":"9.2","naive B-cell":"7.8","plasmacytoid DC":"3.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"9.2","dendritic cells":"3.4"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"HEL":"125.2","K-562":"134.3","RH-30":"160.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004842","HPA056953"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4200000","Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA004842":"AB_1844827","HPA056953":"AB_2683284"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-7"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.8","Tissue RNA - adrenal gland [nTPM]":"1.1","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"1.6","Tissue RNA - basal ganglia [nTPM]":"2.0","Tissue RNA - bone marrow [nTPM]":"95.2","Tissue RNA - breast [nTPM]":"1.0","Tissue RNA - cerebellum [nTPM]":"34.1","Tissue RNA - cerebral cortex [nTPM]":"17.3","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.5","Tissue RNA - duodenum [nTPM]":"1.5","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"8.7","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"98.0","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"12.5","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"0.7","Tissue RNA - lymph node [nTPM]":"4.4","Tissue RNA - medulla oblongata [nTPM]":"26.8","Tissue RNA - midbrain [nTPM]":"32.6","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"62.1","Tissue RNA - pituitary gland [nTPM]":"1.1","Tissue RNA - placenta [nTPM]":"2.1","Tissue RNA - pons [nTPM]":"27.1","Tissue RNA - prostate [nTPM]":"4.2","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"6.3","Tissue RNA - salivary gland [nTPM]":"8.1","Tissue RNA - seminal vesicle [nTPM]":"0.7","Tissue RNA - skeletal muscle [nTPM]":"993.4","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"0.9","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"10.6","Tissue RNA - spleen [nTPM]":"2.2","Tissue RNA - stomach 1 [nTPM]":"4.4","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"8.4","Tissue RNA - thymus [nTPM]":"0.7","Tissue RNA - thyroid gland [nTPM]":"0.6","Tissue RNA - tongue [nTPM]":"629.0","Tissue RNA - tonsil [nTPM]":"4.0","Tissue RNA - urinary bladder [nTPM]":"1.8","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"5.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"16.8","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"2.9","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"4.9","Cell RNA - BJ hTERT+ [nTPM]":"32.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.7","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"7.7","Cell RNA - EFO-21 [nTPM]":"1.5","Cell RNA - fHDF\/TERT166 [nTPM]":"3.5","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"2.8","Cell RNA - HAP1 [nTPM]":"0.8","Cell RNA - HBEC3-KT [nTPM]":"0.5","Cell RNA - HBF TERT88 [nTPM]":"0.7","Cell RNA - HDLM-2 [nTPM]":"3.2","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"125.2","Cell RNA - HeLa [nTPM]":"0.7","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"4.2","Cell RNA - hTCEpi [nTPM]":"0.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.4","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"134.3","Cell RNA - Karpas-707 [nTPM]":"2.8","Cell RNA - LHCN-M2 [nTPM]":"2.1","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"1.6","Cell RNA - NTERA-2 [nTPM]":"1.7","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.9","Cell RNA - RH-30 [nTPM]":"160.2","Cell RNA - RPMI-8226 [nTPM]":"0.8","Cell RNA - RPTEC TERT1 [nTPM]":"0.7","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"2.2","Cell RNA - SH-SY5Y [nTPM]":"1.4","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"2.3","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"5.9","Cell RNA - T-47d [nTPM]":"2.0","Cell RNA - THP-1 [nTPM]":"3.2","Cell RNA - TIME [nTPM]":"0.8","Cell RNA - U-138 MG [nTPM]":"0.5","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"27.6","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"4.7","Cell RNA - U-87 MG [nTPM]":"2.9","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"1.5","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"9.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"7.8","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"3.4","Blood RNA - T-reg [nTPM]":"1.0","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"2.0","Brain RNA - cerebellum [nTPM]":"34.1","Brain RNA - cerebral cortex [nTPM]":"17.3","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"12.5","Brain RNA - medulla oblongata [nTPM]":"26.8","Brain RNA - midbrain [nTPM]":"32.6","Brain RNA - pons [nTPM]":"27.1","Brain RNA - spinal cord [nTPM]":"10.6","Brain RNA - thalamus [nTPM]":"8.4","Brain RNA - white matter [nTPM]":"5.4","Single Cell Type RNA - Adipocytes [nTPM]":"5.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"8.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"15.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"164.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"87.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"7.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"4.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"250.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"2.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.7","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"176.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.7","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"3.7","Single Cell Type RNA - Late spermatids [nTPM]":"6.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"2.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.4","Single Cell Type RNA - Muller glia cells [nTPM]":"1.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.1","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"5.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"51.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"1.7","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.8"},{"Gene":"ANK2","Gene synonym":["CFAP87","FAP87","LQT4"],"Ensembl":"ENSG00000145362","Gene description":"Ankyrin 2","Uniprot":["Q01484"],"Chromosome":"4","Position":"112818032-113384221","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Endocytosis","Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Long QT syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"165.7","retina":"191.2","skeletal muscle":"171.7","tongue":"150.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"1101.2","Bipolar cells":"376.6","Cone photoreceptor cells":"479.6","Excitatory neurons":"1282.0","Horizontal cells":"1431.8","Inhibitory neurons":"1060.7","Oligodendrocyte precursor cells":"497.1","Oligodendrocytes":"1351.0","Rod photoreceptor cells":"484.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"10.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"29.2","ASC TERT1":"32.2","RH-30":"49.6","SH-SY5Y":"24.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008007","CAB015178","HPA035970"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB015178":"AB_2242828","HPA008007":"AB_2667965","HPA035970":"AB_2674893"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.41e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-3"},"Tissue RNA - adipose tissue [nTPM]":"31.0","Tissue RNA - adrenal gland [nTPM]":"13.6","Tissue RNA - amygdala [nTPM]":"94.9","Tissue RNA - appendix [nTPM]":"11.2","Tissue RNA - basal ganglia [nTPM]":"109.0","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"18.3","Tissue RNA - cerebellum [nTPM]":"63.1","Tissue RNA - cerebral cortex [nTPM]":"165.7","Tissue RNA - cervix [nTPM]":"31.6","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"30.1","Tissue RNA - duodenum [nTPM]":"8.5","Tissue RNA - endometrium 1 [nTPM]":"15.8","Tissue RNA - epididymis [nTPM]":"5.9","Tissue RNA - esophagus [nTPM]":"12.9","Tissue RNA - fallopian tube [nTPM]":"9.6","Tissue RNA - gallbladder [nTPM]":"22.5","Tissue RNA - heart muscle [nTPM]":"119.5","Tissue RNA - hippocampal formation [nTPM]":"103.9","Tissue RNA - hypothalamus [nTPM]":"77.5","Tissue RNA - kidney [nTPM]":"110.1","Tissue RNA - liver [nTPM]":"2.4","Tissue RNA - lung [nTPM]":"7.2","Tissue RNA - lymph node [nTPM]":"9.2","Tissue RNA - medulla oblongata [nTPM]":"130.2","Tissue RNA - midbrain [nTPM]":"61.1","Tissue RNA - ovary [nTPM]":"27.3","Tissue RNA - pancreas [nTPM]":"3.2","Tissue RNA - parathyroid gland [nTPM]":"1.2","Tissue RNA - pituitary gland [nTPM]":"19.3","Tissue RNA - placenta [nTPM]":"2.1","Tissue RNA - pons [nTPM]":"119.5","Tissue RNA - prostate [nTPM]":"7.8","Tissue RNA - rectum [nTPM]":"11.4","Tissue RNA - retina [nTPM]":"191.2","Tissue RNA - salivary gland [nTPM]":"6.7","Tissue RNA - seminal vesicle [nTPM]":"13.3","Tissue RNA - skeletal muscle [nTPM]":"171.7","Tissue RNA - skin 1 [nTPM]":"8.7","Tissue RNA - small intestine [nTPM]":"12.7","Tissue RNA - smooth muscle [nTPM]":"24.9","Tissue RNA - spinal cord [nTPM]":"51.9","Tissue RNA - spleen [nTPM]":"28.3","Tissue RNA - stomach 1 [nTPM]":"8.3","Tissue RNA - testis [nTPM]":"9.4","Tissue RNA - thalamus [nTPM]":"84.8","Tissue RNA - thymus [nTPM]":"4.4","Tissue RNA - thyroid gland [nTPM]":"9.6","Tissue RNA - tongue [nTPM]":"150.5","Tissue RNA - tonsil [nTPM]":"7.2","Tissue RNA - urinary bladder [nTPM]":"9.5","Tissue RNA - vagina [nTPM]":"12.3","Tissue RNA - white matter [nTPM]":"116.2","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"2.9","Cell RNA - AF22 [nTPM]":"18.7","Cell RNA - AN3-CA [nTPM]":"5.2","Cell RNA - ASC diff [nTPM]":"29.2","Cell RNA - ASC TERT1 [nTPM]":"32.2","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"1.5","Cell RNA - BJ hTERT+ [nTPM]":"3.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.6","Cell RNA - CACO-2 [nTPM]":"4.2","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"6.9","Cell RNA - EFO-21 [nTPM]":"2.1","Cell RNA - fHDF\/TERT166 [nTPM]":"5.9","Cell RNA - GAMG [nTPM]":"4.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"11.0","Cell RNA - HBEC3-KT [nTPM]":"0.6","Cell RNA - HBF TERT88 [nTPM]":"1.0","Cell RNA - HDLM-2 [nTPM]":"2.3","Cell RNA - HEK 293 [nTPM]":"7.3","Cell RNA - HEL [nTPM]":"4.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"2.9","Cell RNA - HHSteC [nTPM]":"1.7","Cell RNA - HL-60 [nTPM]":"1.9","Cell RNA - HMC-1 [nTPM]":"1.2","Cell RNA - HSkMC [nTPM]":"15.2","Cell RNA - hTCEpi [nTPM]":"3.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.2","Cell RNA - hTERT-HME1 [nTPM]":"6.0","Cell RNA - hTERT-RPE1 [nTPM]":"3.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"9.3","Cell RNA - LHCN-M2 [nTPM]":"5.8","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"9.4","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"2.0","Cell RNA - REH [nTPM]":"0.7","Cell RNA - RH-30 [nTPM]":"49.6","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"13.6","Cell RNA - SH-SY5Y [nTPM]":"24.1","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.7","Cell RNA - SK-MEL-30 [nTPM]":"8.1","Cell RNA - SuSa [nTPM]":"11.7","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"1.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"4.7","Cell RNA - U-2 OS [nTPM]":"2.2","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"3.0","Cell RNA - U-266\/70 [nTPM]":"6.8","Cell RNA - U-266\/84 [nTPM]":"1.8","Cell RNA - U-698 [nTPM]":"0.9","Cell RNA - U-87 MG [nTPM]":"20.1","Cell RNA - U-937 [nTPM]":"0.6","Cell RNA - WM-115 [nTPM]":"7.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"94.9","Brain RNA - basal ganglia [nTPM]":"109.0","Brain RNA - cerebellum [nTPM]":"63.1","Brain RNA - cerebral cortex [nTPM]":"165.7","Brain RNA - hippocampal formation [nTPM]":"103.9","Brain RNA - hypothalamus [nTPM]":"77.5","Brain RNA - medulla oblongata [nTPM]":"130.2","Brain RNA - midbrain [nTPM]":"61.1","Brain RNA - pons [nTPM]":"119.5","Brain RNA - spinal cord [nTPM]":"51.9","Brain RNA - thalamus [nTPM]":"84.8","Brain RNA - white matter [nTPM]":"116.2","Single Cell Type RNA - Adipocytes [nTPM]":"6.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.9","Single Cell Type RNA - Astrocytes [nTPM]":"1101.2","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"376.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"188.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"479.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"111.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"36.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.0","Single Cell Type RNA - Endothelial cells [nTPM]":"6.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"66.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1282.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"79.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.2","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"81.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.0","Single Cell Type RNA - Horizontal cells [nTPM]":"1431.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1060.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"19.7","Single Cell Type RNA - Late spermatids [nTPM]":"49.8","Single Cell Type RNA - Leydig cells [nTPM]":"36.4","Single Cell Type RNA - Macrophages [nTPM]":"2.9","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"90.9","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"44.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"497.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1351.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"5.0","Single Cell Type RNA - Peritubular cells [nTPM]":"30.1","Single Cell Type RNA - Plasma cells [nTPM]":"0.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"127.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"484.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"24.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.5","Single Cell Type RNA - Spermatocytes [nTPM]":"2.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.9","Single Cell Type RNA - Theca cells [nTPM]":"2.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"ANKH","Gene synonym":["ANK","CCAL2","CMDJ","CPPDD","HANK","SLC62A1"],"Ensembl":"ENSG00000154122","Gene description":"ANKH inorganic pyrophosphate transport regulator","Uniprot":["Q9HCJ1"],"Chromosome":"5","Position":"14704800-14871778","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Phosphate transport","Transport"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"160.1","Hofbauer cells":"208.8","Inhibitory neurons":"214.5","Oligodendrocytes":"261.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"47.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA068104"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA068104":"AB_2685954"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.62e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.9","Tissue RNA - adrenal gland [nTPM]":"10.6","Tissue RNA - amygdala [nTPM]":"22.1","Tissue RNA - appendix [nTPM]":"6.6","Tissue RNA - basal ganglia [nTPM]":"23.8","Tissue RNA - bone marrow [nTPM]":"8.0","Tissue RNA - breast [nTPM]":"9.9","Tissue RNA - cerebellum [nTPM]":"33.9","Tissue RNA - cerebral cortex [nTPM]":"29.3","Tissue RNA - cervix [nTPM]":"5.5","Tissue RNA - choroid plexus [nTPM]":"26.6","Tissue RNA - colon [nTPM]":"12.8","Tissue RNA - duodenum [nTPM]":"16.8","Tissue RNA - endometrium 1 [nTPM]":"7.1","Tissue RNA - epididymis [nTPM]":"4.9","Tissue RNA - esophagus [nTPM]":"7.4","Tissue RNA - fallopian tube [nTPM]":"7.7","Tissue RNA - gallbladder [nTPM]":"9.4","Tissue RNA - heart muscle [nTPM]":"32.2","Tissue RNA - hippocampal formation [nTPM]":"22.5","Tissue RNA - hypothalamus [nTPM]":"25.5","Tissue RNA - kidney [nTPM]":"8.1","Tissue RNA - liver [nTPM]":"21.4","Tissue RNA - lung [nTPM]":"7.1","Tissue RNA - lymph node [nTPM]":"8.5","Tissue RNA - medulla oblongata [nTPM]":"25.3","Tissue RNA - midbrain [nTPM]":"28.2","Tissue RNA - ovary [nTPM]":"16.0","Tissue RNA - pancreas [nTPM]":"15.2","Tissue RNA - parathyroid gland [nTPM]":"19.2","Tissue RNA - pituitary gland [nTPM]":"22.8","Tissue RNA - placenta [nTPM]":"8.5","Tissue RNA - pons [nTPM]":"25.1","Tissue RNA - prostate [nTPM]":"32.7","Tissue RNA - rectum [nTPM]":"11.4","Tissue RNA - retina [nTPM]":"25.1","Tissue RNA - salivary gland [nTPM]":"14.3","Tissue RNA - seminal vesicle [nTPM]":"9.2","Tissue RNA - skeletal muscle [nTPM]":"40.9","Tissue RNA - skin 1 [nTPM]":"20.3","Tissue RNA - small intestine [nTPM]":"15.0","Tissue RNA - smooth muscle [nTPM]":"8.5","Tissue RNA - spinal cord [nTPM]":"24.9","Tissue RNA - spleen [nTPM]":"6.8","Tissue RNA - stomach 1 [nTPM]":"7.3","Tissue RNA - testis [nTPM]":"1.9","Tissue RNA - thalamus [nTPM]":"26.8","Tissue RNA - thymus [nTPM]":"11.5","Tissue RNA - thyroid gland [nTPM]":"10.7","Tissue RNA - tongue [nTPM]":"37.6","Tissue RNA - tonsil [nTPM]":"14.1","Tissue RNA - urinary bladder [nTPM]":"7.3","Tissue RNA - vagina [nTPM]":"7.4","Tissue RNA - white matter [nTPM]":"28.8","Cell RNA - A-431 [nTPM]":"7.2","Cell RNA - A549 [nTPM]":"5.4","Cell RNA - AF22 [nTPM]":"6.7","Cell RNA - AN3-CA [nTPM]":"1.1","Cell RNA - ASC diff [nTPM]":"13.8","Cell RNA - ASC TERT1 [nTPM]":"32.3","Cell RNA - BEWO [nTPM]":"3.2","Cell RNA - BJ [nTPM]":"6.8","Cell RNA - BJ hTERT+ [nTPM]":"13.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.7","Cell RNA - CACO-2 [nTPM]":"4.3","Cell RNA - CAPAN-2 [nTPM]":"9.0","Cell RNA - Daudi [nTPM]":"16.9","Cell RNA - EFO-21 [nTPM]":"15.7","Cell RNA - fHDF\/TERT166 [nTPM]":"9.4","Cell RNA - GAMG [nTPM]":"6.2","Cell RNA - HaCaT [nTPM]":"4.6","Cell RNA - HAP1 [nTPM]":"4.6","Cell RNA - HBEC3-KT [nTPM]":"7.5","Cell RNA - HBF TERT88 [nTPM]":"3.0","Cell RNA - HDLM-2 [nTPM]":"6.7","Cell RNA - HEK 293 [nTPM]":"11.3","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"47.8","Cell RNA - Hep G2 [nTPM]":"11.6","Cell RNA - HHSteC [nTPM]":"4.6","Cell RNA - HL-60 [nTPM]":"4.1","Cell RNA - HMC-1 [nTPM]":"1.3","Cell RNA - HSkMC [nTPM]":"10.2","Cell RNA - hTCEpi [nTPM]":"13.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.1","Cell RNA - hTERT-HME1 [nTPM]":"9.2","Cell RNA - hTERT-RPE1 [nTPM]":"9.2","Cell RNA - HUVEC TERT2 [nTPM]":"5.5","Cell RNA - JURKAT [nTPM]":"12.3","Cell RNA - K-562 [nTPM]":"3.5","Cell RNA - Karpas-707 [nTPM]":"35.2","Cell RNA - LHCN-M2 [nTPM]":"8.7","Cell RNA - MCF7 [nTPM]":"9.6","Cell RNA - MOLT-4 [nTPM]":"6.9","Cell RNA - NB-4 [nTPM]":"13.3","Cell RNA - NTERA-2 [nTPM]":"2.6","Cell RNA - OE19 [nTPM]":"9.5","Cell RNA - PC-3 [nTPM]":"6.0","Cell RNA - REH [nTPM]":"9.8","Cell RNA - RH-30 [nTPM]":"3.3","Cell RNA - RPMI-8226 [nTPM]":"15.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"2.3","Cell RNA - SCLC-21H [nTPM]":"16.4","Cell RNA - SH-SY5Y [nTPM]":"4.5","Cell RNA - SiHa [nTPM]":"33.3","Cell RNA - SK-BR-3 [nTPM]":"5.3","Cell RNA - SK-MEL-30 [nTPM]":"7.5","Cell RNA - SuSa [nTPM]":"6.1","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"1.5","Cell RNA - TIME [nTPM]":"5.4","Cell RNA - U-138 MG [nTPM]":"6.9","Cell RNA - U-2 OS [nTPM]":"6.9","Cell RNA - U-2197 [nTPM]":"11.5","Cell RNA - U-251 MG [nTPM]":"12.6","Cell RNA - U-266\/70 [nTPM]":"9.2","Cell RNA - U-266\/84 [nTPM]":"9.3","Cell RNA - U-698 [nTPM]":"13.0","Cell RNA - U-87 MG [nTPM]":"23.8","Cell RNA - U-937 [nTPM]":"15.1","Cell RNA - WM-115 [nTPM]":"29.0","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.4","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"2.3","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"2.9","Blood RNA - memory CD8 T-cell [nTPM]":"2.3","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"1.6","Blood RNA - naive CD4 T-cell [nTPM]":"3.3","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"4.6","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"22.1","Brain RNA - basal ganglia [nTPM]":"23.8","Brain RNA - cerebellum [nTPM]":"33.9","Brain RNA - cerebral cortex [nTPM]":"29.3","Brain RNA - hippocampal formation [nTPM]":"22.5","Brain RNA - hypothalamus [nTPM]":"25.5","Brain RNA - medulla oblongata [nTPM]":"25.3","Brain RNA - midbrain [nTPM]":"28.2","Brain RNA - pons [nTPM]":"25.1","Brain RNA - spinal cord [nTPM]":"24.9","Brain RNA - thalamus [nTPM]":"26.8","Brain RNA - white matter [nTPM]":"28.8","Single Cell Type RNA - Adipocytes [nTPM]":"50.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.1","Single Cell Type RNA - Astrocytes [nTPM]":"64.6","Single Cell Type RNA - B-cells [nTPM]":"15.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"25.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"79.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"33.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"40.9","Single Cell Type RNA - Bipolar cells [nTPM]":"58.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"73.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"10.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"127.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"76.4","Single Cell Type RNA - dendritic cells [nTPM]":"21.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"58.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.7","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.9","Single Cell Type RNA - Endothelial cells [nTPM]":"25.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"41.8","Single Cell Type RNA - Erythroid cells [nTPM]":"69.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"160.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.1","Single Cell Type RNA - Fibroblasts [nTPM]":"25.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.9","Single Cell Type RNA - granulocytes [nTPM]":"17.7","Single Cell Type RNA - Granulosa cells [nTPM]":"9.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.5","Single Cell Type RNA - Hepatocytes [nTPM]":"32.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"208.8","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"214.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"37.7","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"89.3","Single Cell Type RNA - Langerhans cells [nTPM]":"29.9","Single Cell Type RNA - Late spermatids [nTPM]":"1.9","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"42.6","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"106.8","Single Cell Type RNA - monocytes [nTPM]":"3.4","Single Cell Type RNA - Muller glia cells [nTPM]":"20.1","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"95.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"261.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.8","Single Cell Type RNA - Paneth cells [nTPM]":"31.4","Single Cell Type RNA - Peritubular cells [nTPM]":"31.6","Single Cell Type RNA - Plasma cells [nTPM]":"14.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"55.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"44.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"50.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"32.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.3","Single Cell Type RNA - Spermatocytes [nTPM]":"2.3","Single Cell Type RNA - Spermatogonia [nTPM]":"7.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"42.0","Single Cell Type RNA - T-cells [nTPM]":"25.9","Single Cell Type RNA - Theca cells [nTPM]":"8.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"37.3","Single Cell Type RNA - Urothelial cells [nTPM]":"22.3"},{"Gene":"ANO10","Gene synonym":["FLJ10375","MGC47890","SCAR10","TMEM16K"],"Ensembl":"ENSG00000160746","Gene description":"Anoctamin 10","Uniprot":["Q9NW15"],"Chromosome":"3","Position":"43354859-43691594","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"123.3","Excitatory neurons":"77.4","Inhibitory neurons":"97.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016624","HPA051569"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA016624":null,"HPA051569":"AB_2681537"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.70e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.11e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.19e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.41e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.83e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Tissue RNA - adipose tissue [nTPM]":"26.6","Tissue RNA - adrenal gland [nTPM]":"14.1","Tissue RNA - amygdala [nTPM]":"17.6","Tissue RNA - appendix [nTPM]":"15.1","Tissue RNA - basal ganglia [nTPM]":"18.6","Tissue RNA - bone marrow [nTPM]":"33.0","Tissue RNA - breast [nTPM]":"21.8","Tissue RNA - cerebellum [nTPM]":"23.9","Tissue RNA - cerebral cortex [nTPM]":"20.9","Tissue RNA - cervix [nTPM]":"22.3","Tissue RNA - choroid plexus [nTPM]":"18.4","Tissue RNA - colon [nTPM]":"39.4","Tissue RNA - duodenum [nTPM]":"61.1","Tissue RNA - endometrium 1 [nTPM]":"21.6","Tissue RNA - epididymis [nTPM]":"13.6","Tissue RNA - esophagus [nTPM]":"25.3","Tissue RNA - fallopian tube [nTPM]":"13.9","Tissue RNA - gallbladder [nTPM]":"19.4","Tissue RNA - heart muscle [nTPM]":"12.7","Tissue RNA - hippocampal formation [nTPM]":"18.1","Tissue RNA - hypothalamus [nTPM]":"21.1","Tissue RNA - kidney [nTPM]":"29.9","Tissue RNA - liver [nTPM]":"14.1","Tissue RNA - lung [nTPM]":"16.9","Tissue RNA - lymph node [nTPM]":"7.6","Tissue RNA - medulla oblongata [nTPM]":"22.7","Tissue RNA - midbrain [nTPM]":"22.9","Tissue RNA - ovary [nTPM]":"13.9","Tissue RNA - pancreas [nTPM]":"15.2","Tissue RNA - parathyroid gland [nTPM]":"23.7","Tissue RNA - pituitary gland [nTPM]":"13.9","Tissue RNA - placenta [nTPM]":"18.1","Tissue RNA - pons [nTPM]":"23.2","Tissue RNA - prostate [nTPM]":"14.2","Tissue RNA - rectum [nTPM]":"33.7","Tissue RNA - retina [nTPM]":"10.1","Tissue RNA - salivary gland [nTPM]":"28.6","Tissue RNA - seminal vesicle [nTPM]":"20.2","Tissue RNA - skeletal muscle [nTPM]":"15.5","Tissue RNA - skin 1 [nTPM]":"32.0","Tissue RNA - small intestine [nTPM]":"54.7","Tissue RNA - smooth muscle [nTPM]":"28.0","Tissue RNA - spinal cord [nTPM]":"19.6","Tissue RNA - spleen [nTPM]":"9.1","Tissue RNA - stomach 1 [nTPM]":"13.5","Tissue RNA - testis [nTPM]":"13.0","Tissue RNA - thalamus [nTPM]":"19.8","Tissue RNA - thymus [nTPM]":"7.1","Tissue RNA - thyroid gland [nTPM]":"24.5","Tissue RNA - tongue [nTPM]":"11.6","Tissue RNA - tonsil [nTPM]":"9.7","Tissue RNA - urinary bladder [nTPM]":"18.1","Tissue RNA - vagina [nTPM]":"21.5","Tissue RNA - white matter [nTPM]":"24.1","Cell RNA - A-431 [nTPM]":"30.6","Cell RNA - A549 [nTPM]":"23.6","Cell RNA - AF22 [nTPM]":"26.1","Cell RNA - AN3-CA [nTPM]":"27.4","Cell RNA - ASC diff [nTPM]":"101.1","Cell RNA - ASC TERT1 [nTPM]":"53.5","Cell RNA - BEWO [nTPM]":"31.2","Cell RNA - BJ [nTPM]":"87.7","Cell RNA - BJ hTERT+ [nTPM]":"141.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"42.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"54.4","Cell RNA - CACO-2 [nTPM]":"16.2","Cell RNA - CAPAN-2 [nTPM]":"27.5","Cell RNA - Daudi [nTPM]":"3.1","Cell RNA - EFO-21 [nTPM]":"27.4","Cell RNA - fHDF\/TERT166 [nTPM]":"114.8","Cell RNA - GAMG [nTPM]":"43.1","Cell RNA - HaCaT [nTPM]":"16.3","Cell RNA - HAP1 [nTPM]":"20.6","Cell RNA - HBEC3-KT [nTPM]":"47.0","Cell RNA - HBF TERT88 [nTPM]":"52.6","Cell RNA - HDLM-2 [nTPM]":"33.6","Cell RNA - HEK 293 [nTPM]":"14.2","Cell RNA - HEL [nTPM]":"39.4","Cell RNA - HeLa [nTPM]":"28.7","Cell RNA - Hep G2 [nTPM]":"17.7","Cell RNA - HHSteC [nTPM]":"43.9","Cell RNA - HL-60 [nTPM]":"7.2","Cell RNA - HMC-1 [nTPM]":"31.1","Cell RNA - HSkMC [nTPM]":"50.5","Cell RNA - hTCEpi [nTPM]":"36.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"53.6","Cell RNA - hTERT-HME1 [nTPM]":"71.8","Cell RNA - hTERT-RPE1 [nTPM]":"79.4","Cell RNA - HUVEC TERT2 [nTPM]":"100.3","Cell RNA - JURKAT [nTPM]":"18.7","Cell RNA - K-562 [nTPM]":"30.8","Cell RNA - Karpas-707 [nTPM]":"24.9","Cell RNA - LHCN-M2 [nTPM]":"95.2","Cell RNA - MCF7 [nTPM]":"20.8","Cell RNA - MOLT-4 [nTPM]":"7.8","Cell RNA - NB-4 [nTPM]":"5.2","Cell RNA - NTERA-2 [nTPM]":"31.3","Cell RNA - OE19 [nTPM]":"23.7","Cell RNA - PC-3 [nTPM]":"28.6","Cell RNA - REH [nTPM]":"6.3","Cell RNA - RH-30 [nTPM]":"18.7","Cell RNA - RPMI-8226 [nTPM]":"10.2","Cell RNA - RPTEC TERT1 [nTPM]":"85.5","Cell RNA - RT4 [nTPM]":"31.4","Cell RNA - SCLC-21H [nTPM]":"6.4","Cell RNA - SH-SY5Y [nTPM]":"19.4","Cell RNA - SiHa [nTPM]":"34.4","Cell RNA - SK-BR-3 [nTPM]":"27.0","Cell RNA - SK-MEL-30 [nTPM]":"19.8","Cell RNA - SuSa [nTPM]":"45.3","Cell RNA - T-47d [nTPM]":"59.5","Cell RNA - THP-1 [nTPM]":"14.5","Cell RNA - TIME [nTPM]":"84.7","Cell RNA - U-138 MG [nTPM]":"66.2","Cell RNA - U-2 OS [nTPM]":"24.4","Cell RNA - U-2197 [nTPM]":"70.2","Cell RNA - U-251 MG [nTPM]":"40.7","Cell RNA - U-266\/70 [nTPM]":"15.7","Cell RNA - U-266\/84 [nTPM]":"22.9","Cell RNA - U-698 [nTPM]":"1.1","Cell RNA - U-87 MG [nTPM]":"60.2","Cell RNA - U-937 [nTPM]":"14.6","Cell RNA - WM-115 [nTPM]":"44.2","Blood RNA - basophil [nTPM]":"7.4","Blood RNA - classical monocyte [nTPM]":"19.0","Blood RNA - eosinophil [nTPM]":"1.4","Blood RNA - gdT-cell [nTPM]":"6.7","Blood RNA - intermediate monocyte [nTPM]":"11.1","Blood RNA - MAIT T-cell [nTPM]":"3.8","Blood RNA - memory B-cell [nTPM]":"2.7","Blood RNA - memory CD4 T-cell [nTPM]":"4.6","Blood RNA - memory CD8 T-cell [nTPM]":"4.5","Blood RNA - myeloid DC [nTPM]":"13.1","Blood RNA - naive B-cell [nTPM]":"2.5","Blood RNA - naive CD4 T-cell [nTPM]":"3.9","Blood RNA - naive CD8 T-cell [nTPM]":"6.0","Blood RNA - neutrophil [nTPM]":"32.8","Blood RNA - NK-cell [nTPM]":"9.7","Blood RNA - non-classical monocyte [nTPM]":"12.7","Blood RNA - plasmacytoid DC [nTPM]":"2.3","Blood RNA - T-reg [nTPM]":"5.4","Blood RNA - total PBMC [nTPM]":"7.0","Brain RNA - amygdala [nTPM]":"17.6","Brain RNA - basal ganglia [nTPM]":"18.6","Brain RNA - cerebellum [nTPM]":"23.9","Brain RNA - cerebral cortex [nTPM]":"20.9","Brain RNA - hippocampal formation [nTPM]":"18.1","Brain RNA - hypothalamus [nTPM]":"21.1","Brain RNA - medulla oblongata [nTPM]":"22.7","Brain RNA - midbrain [nTPM]":"22.9","Brain RNA - pons [nTPM]":"23.2","Brain RNA - spinal cord [nTPM]":"19.6","Brain RNA - thalamus [nTPM]":"19.8","Brain RNA - white matter [nTPM]":"24.1","Single Cell Type RNA - Adipocytes [nTPM]":"24.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.2","Single Cell Type RNA - Astrocytes [nTPM]":"70.2","Single Cell Type RNA - B-cells [nTPM]":"4.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"8.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"13.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.4","Single Cell Type RNA - dendritic cells [nTPM]":"3.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"38.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"123.3","Single Cell Type RNA - Ductal cells [nTPM]":"21.6","Single Cell Type RNA - Early spermatids [nTPM]":"2.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.6","Single Cell Type RNA - Endothelial cells [nTPM]":"17.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"11.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"77.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.5","Single Cell Type RNA - Fibroblasts [nTPM]":"10.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"31.2","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"6.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.6","Single Cell Type RNA - Hepatocytes [nTPM]":"10.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.6","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"97.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.8","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"9.6","Single Cell Type RNA - Langerhans cells [nTPM]":"5.3","Single Cell Type RNA - Late spermatids [nTPM]":"5.2","Single Cell Type RNA - Leydig cells [nTPM]":"5.6","Single Cell Type RNA - Macrophages [nTPM]":"9.1","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"69.3","Single Cell Type RNA - monocytes [nTPM]":"9.2","Single Cell Type RNA - Muller glia cells [nTPM]":"17.1","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"71.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"46.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.7","Single Cell Type RNA - Paneth cells [nTPM]":"22.1","Single Cell Type RNA - Peritubular cells [nTPM]":"10.1","Single Cell Type RNA - Plasma cells [nTPM]":"2.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"58.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.7","Single Cell Type RNA - Spermatocytes [nTPM]":"17.1","Single Cell Type RNA - Spermatogonia [nTPM]":"23.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.1","Single Cell Type RNA - T-cells [nTPM]":"5.8","Single Cell Type RNA - Theca cells [nTPM]":"6.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.9","Single Cell Type RNA - Urothelial cells [nTPM]":"4.8"},{"Gene":"ANO3","Gene synonym":["C11orf25","DYT23","GENX-3947","TMEM16C"],"Ensembl":"ENSG00000134343","Gene description":"Anoctamin 3","Uniprot":["Q9BYT9"],"Chromosome":"11","Position":"26188842-26663289","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Dystonia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"19","RNA tissue specific nTPM":{"brain":"59.2","epididymis":"57.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Excitatory neurons":"201.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"basal ganglia":"59.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"GAMG":"1.9","HDLM-2":"6.8","U-2 OS":"1.6","U-2197":"4.3"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"158.9"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"7","RNA pig brain regional specific nTPM":{"basal ganglia":"180.1"},"Antibody":["HPA041629"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041629":"AB_10793969"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.48e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.0","Tissue RNA - adrenal gland [nTPM]":"0.8","Tissue RNA - amygdala [nTPM]":"4.3","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"59.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"11.8","Tissue RNA - cervix [nTPM]":"0.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"57.4","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"1.8","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"7.7","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"1.0","Tissue RNA - liver [nTPM]":"1.1","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"1.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"1.9","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"1.9","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"1.0","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"1.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"1.1","Cell RNA - ASC TERT1 [nTPM]":"1.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"1.1","Cell RNA - GAMG [nTPM]":"1.9","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"6.8","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.4","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"1.2","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.7","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.6","Cell RNA - U-2197 [nTPM]":"4.3","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"1.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.3","Brain RNA - basal ganglia [nTPM]":"59.2","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"11.8","Brain RNA - hippocampal formation [nTPM]":"7.7","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"1.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"1.9","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"1.7","Single Cell Type RNA - Adipocytes [nTPM]":"1.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.0","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"12.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"201.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"0.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"38.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.7","Single Cell Type RNA - Spermatocytes [nTPM]":"3.8","Single Cell Type RNA - Spermatogonia [nTPM]":"2.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"ANO5","Gene synonym":["GDD1","LGMD2L","TMEM16E"],"Ensembl":"ENSG00000171714","Gene description":"Anoctamin 5","Uniprot":["Q75V66"],"Chromosome":"11","Position":"21799934-22283357","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Limb-girdle muscular dystrophy","Osteogenesis imperfecta"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"heart muscle":"24.9","parathyroid gland":"17.0","skeletal muscle":"65.5","tongue":"50.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Astrocytes":"67.9","Cardiomyocytes":"86.2","Excitatory neurons":"166.6","Inhibitory neurons":"136.4","Oligodendrocyte precursor cells":"81.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"4.9","HAP1":"5.0","HEK 293":"6.6","NTERA-2":"3.5","RPTEC TERT1":"3.2","U-266\/84":"3.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058857"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA058857":"AB_2683835"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.50e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.9","Tissue RNA - adrenal gland [nTPM]":"4.5","Tissue RNA - amygdala [nTPM]":"1.9","Tissue RNA - appendix [nTPM]":"0.8","Tissue RNA - basal ganglia [nTPM]":"3.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.7","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"8.9","Tissue RNA - cervix [nTPM]":"1.6","Tissue RNA - choroid plexus [nTPM]":"3.0","Tissue RNA - colon [nTPM]":"2.6","Tissue RNA - duodenum [nTPM]":"3.3","Tissue RNA - endometrium 1 [nTPM]":"1.5","Tissue RNA - epididymis [nTPM]":"1.3","Tissue RNA - esophagus [nTPM]":"2.0","Tissue RNA - fallopian tube [nTPM]":"0.8","Tissue RNA - gallbladder [nTPM]":"1.7","Tissue RNA - heart muscle [nTPM]":"24.9","Tissue RNA - hippocampal formation [nTPM]":"4.0","Tissue RNA - hypothalamus [nTPM]":"2.2","Tissue RNA - kidney [nTPM]":"3.6","Tissue RNA - liver [nTPM]":"2.1","Tissue RNA - lung [nTPM]":"1.2","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"2.7","Tissue RNA - midbrain [nTPM]":"2.1","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"3.9","Tissue RNA - parathyroid gland [nTPM]":"17.0","Tissue RNA - pituitary gland [nTPM]":"3.4","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"2.2","Tissue RNA - prostate [nTPM]":"4.2","Tissue RNA - rectum [nTPM]":"3.3","Tissue RNA - retina [nTPM]":"2.1","Tissue RNA - salivary gland [nTPM]":"2.6","Tissue RNA - seminal vesicle [nTPM]":"4.1","Tissue RNA - skeletal muscle [nTPM]":"65.5","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"2.5","Tissue RNA - smooth muscle [nTPM]":"2.7","Tissue RNA - spinal cord [nTPM]":"0.4","Tissue RNA - spleen [nTPM]":"0.7","Tissue RNA - stomach 1 [nTPM]":"3.0","Tissue RNA - testis [nTPM]":"1.8","Tissue RNA - thalamus [nTPM]":"2.4","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"4.7","Tissue RNA - tongue [nTPM]":"50.4","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"2.0","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"3.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"4.9","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"5.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"6.6","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.8","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"1.4","Cell RNA - Karpas-707 [nTPM]":"2.5","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"3.5","Cell RNA - OE19 [nTPM]":"2.6","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"3.2","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"2.7","Cell RNA - SH-SY5Y [nTPM]":"2.6","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"2.1","Cell RNA - T-47d [nTPM]":"2.1","Cell RNA - THP-1 [nTPM]":"1.9","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.9","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"2.0","Cell RNA - U-266\/84 [nTPM]":"3.7","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"2.8","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.9","Brain RNA - basal ganglia [nTPM]":"3.0","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"8.9","Brain RNA - hippocampal formation [nTPM]":"4.0","Brain RNA - hypothalamus [nTPM]":"2.2","Brain RNA - medulla oblongata [nTPM]":"2.7","Brain RNA - midbrain [nTPM]":"2.1","Brain RNA - pons [nTPM]":"2.2","Brain RNA - spinal cord [nTPM]":"0.4","Brain RNA - thalamus [nTPM]":"2.4","Brain RNA - white matter [nTPM]":"3.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.9","Single Cell Type RNA - Astrocytes [nTPM]":"67.9","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"6.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"86.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.3","Single Cell Type RNA - Early spermatids [nTPM]":"5.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"3.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"166.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"3.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"5.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.5","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"136.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"1.4","Single Cell Type RNA - Late spermatids [nTPM]":"2.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.6","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"1.9","Single Cell Type RNA - Muller glia cells [nTPM]":"2.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"81.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.0","Single Cell Type RNA - Paneth cells [nTPM]":"4.4","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.4","Single Cell Type RNA - Spermatocytes [nTPM]":"11.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"1.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"ANO6","Gene synonym":["DKFZp313M0720","TMEM16F"],"Ensembl":"ENSG00000177119","Gene description":"Anoctamin 6","Uniprot":["Q4KMQ2"],"Chromosome":"12","Position":"45215987-45482280","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Lipid transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038958"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"47000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA038958":"AB_10672835"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.56e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.82e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Tissue RNA - adipose tissue [nTPM]":"86.4","Tissue RNA - adrenal gland [nTPM]":"25.9","Tissue RNA - amygdala [nTPM]":"7.4","Tissue RNA - appendix [nTPM]":"16.8","Tissue RNA - basal ganglia [nTPM]":"8.0","Tissue RNA - bone marrow [nTPM]":"9.8","Tissue RNA - breast [nTPM]":"27.5","Tissue RNA - cerebellum [nTPM]":"7.9","Tissue RNA - cerebral cortex [nTPM]":"8.4","Tissue RNA - cervix [nTPM]":"28.9","Tissue RNA - choroid plexus [nTPM]":"13.8","Tissue RNA - colon [nTPM]":"29.9","Tissue RNA - duodenum [nTPM]":"36.2","Tissue RNA - endometrium 1 [nTPM]":"38.9","Tissue RNA - epididymis [nTPM]":"25.6","Tissue RNA - esophagus [nTPM]":"25.0","Tissue RNA - fallopian tube [nTPM]":"27.2","Tissue RNA - gallbladder [nTPM]":"31.6","Tissue RNA - heart muscle [nTPM]":"27.7","Tissue RNA - hippocampal formation [nTPM]":"7.2","Tissue RNA - hypothalamus [nTPM]":"10.5","Tissue RNA - kidney [nTPM]":"36.2","Tissue RNA - liver [nTPM]":"56.9","Tissue RNA - lung [nTPM]":"40.2","Tissue RNA - lymph node [nTPM]":"13.4","Tissue RNA - medulla oblongata [nTPM]":"10.4","Tissue RNA - midbrain [nTPM]":"8.5","Tissue RNA - ovary [nTPM]":"56.6","Tissue RNA - pancreas [nTPM]":"25.3","Tissue RNA - parathyroid gland [nTPM]":"58.8","Tissue RNA - pituitary gland [nTPM]":"6.9","Tissue RNA - placenta [nTPM]":"50.5","Tissue RNA - pons [nTPM]":"10.1","Tissue RNA - prostate [nTPM]":"29.9","Tissue RNA - rectum [nTPM]":"15.0","Tissue RNA - retina [nTPM]":"3.6","Tissue RNA - salivary gland [nTPM]":"25.4","Tissue RNA - seminal vesicle [nTPM]":"37.1","Tissue RNA - skeletal muscle [nTPM]":"56.0","Tissue RNA - skin 1 [nTPM]":"12.0","Tissue RNA - small intestine [nTPM]":"51.4","Tissue RNA - smooth muscle [nTPM]":"48.4","Tissue RNA - spinal cord [nTPM]":"9.0","Tissue RNA - spleen [nTPM]":"16.0","Tissue RNA - stomach 1 [nTPM]":"13.8","Tissue RNA - testis [nTPM]":"11.8","Tissue RNA - thalamus [nTPM]":"9.1","Tissue RNA - thymus [nTPM]":"24.9","Tissue RNA - thyroid gland [nTPM]":"13.2","Tissue RNA - tongue [nTPM]":"46.3","Tissue RNA - tonsil [nTPM]":"12.8","Tissue RNA - urinary bladder [nTPM]":"35.0","Tissue RNA - vagina [nTPM]":"16.0","Tissue RNA - white matter [nTPM]":"9.3","Cell RNA - A-431 [nTPM]":"41.5","Cell RNA - A549 [nTPM]":"44.3","Cell RNA - AF22 [nTPM]":"25.7","Cell RNA - AN3-CA [nTPM]":"35.4","Cell RNA - ASC diff [nTPM]":"119.1","Cell RNA - ASC TERT1 [nTPM]":"61.7","Cell RNA - BEWO [nTPM]":"97.4","Cell RNA - BJ [nTPM]":"57.4","Cell RNA - BJ hTERT+ [nTPM]":"72.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"38.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"36.3","Cell RNA - CACO-2 [nTPM]":"71.9","Cell RNA - CAPAN-2 [nTPM]":"61.5","Cell RNA - Daudi [nTPM]":"21.1","Cell RNA - EFO-21 [nTPM]":"52.2","Cell RNA - fHDF\/TERT166 [nTPM]":"92.0","Cell RNA - GAMG [nTPM]":"34.9","Cell RNA - HaCaT [nTPM]":"54.0","Cell RNA - HAP1 [nTPM]":"24.1","Cell RNA - HBEC3-KT [nTPM]":"32.3","Cell RNA - HBF TERT88 [nTPM]":"45.6","Cell RNA - HDLM-2 [nTPM]":"31.4","Cell RNA - HEK 293 [nTPM]":"16.9","Cell RNA - HEL [nTPM]":"25.0","Cell RNA - HeLa [nTPM]":"17.8","Cell RNA - Hep G2 [nTPM]":"62.1","Cell RNA - HHSteC [nTPM]":"37.8","Cell RNA - HL-60 [nTPM]":"39.5","Cell RNA - HMC-1 [nTPM]":"19.4","Cell RNA - HSkMC [nTPM]":"51.7","Cell RNA - hTCEpi [nTPM]":"31.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"33.0","Cell RNA - hTERT-HME1 [nTPM]":"48.7","Cell RNA - hTERT-RPE1 [nTPM]":"95.4","Cell RNA - HUVEC TERT2 [nTPM]":"52.6","Cell RNA - JURKAT [nTPM]":"44.5","Cell RNA - K-562 [nTPM]":"19.3","Cell RNA - Karpas-707 [nTPM]":"34.0","Cell RNA - LHCN-M2 [nTPM]":"42.7","Cell RNA - MCF7 [nTPM]":"11.2","Cell RNA - MOLT-4 [nTPM]":"41.5","Cell RNA - NB-4 [nTPM]":"13.2","Cell RNA - NTERA-2 [nTPM]":"28.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"18.0","Cell RNA - REH [nTPM]":"23.4","Cell RNA - RH-30 [nTPM]":"33.3","Cell RNA - RPMI-8226 [nTPM]":"24.4","Cell RNA - RPTEC TERT1 [nTPM]":"36.9","Cell RNA - RT4 [nTPM]":"63.1","Cell RNA - SCLC-21H [nTPM]":"11.7","Cell RNA - SH-SY5Y [nTPM]":"39.9","Cell RNA - SiHa [nTPM]":"59.9","Cell RNA - SK-BR-3 [nTPM]":"36.8","Cell RNA - SK-MEL-30 [nTPM]":"27.9","Cell RNA - SuSa [nTPM]":"67.7","Cell RNA - T-47d [nTPM]":"43.3","Cell RNA - THP-1 [nTPM]":"62.8","Cell RNA - TIME [nTPM]":"70.6","Cell RNA - U-138 MG [nTPM]":"41.2","Cell RNA - U-2 OS [nTPM]":"26.1","Cell RNA - U-2197 [nTPM]":"41.8","Cell RNA - U-251 MG [nTPM]":"29.3","Cell RNA - U-266\/70 [nTPM]":"18.3","Cell RNA - U-266\/84 [nTPM]":"21.5","Cell RNA - U-698 [nTPM]":"25.8","Cell RNA - U-87 MG [nTPM]":"37.3","Cell RNA - U-937 [nTPM]":"122.8","Cell RNA - WM-115 [nTPM]":"33.4","Blood RNA - basophil [nTPM]":"3.1","Blood RNA - classical monocyte [nTPM]":"5.9","Blood RNA - eosinophil [nTPM]":"1.4","Blood RNA - gdT-cell [nTPM]":"2.4","Blood RNA - intermediate monocyte [nTPM]":"6.9","Blood RNA - MAIT T-cell [nTPM]":"2.5","Blood RNA - memory B-cell [nTPM]":"1.4","Blood RNA - memory CD4 T-cell [nTPM]":"2.2","Blood RNA - memory CD8 T-cell [nTPM]":"2.0","Blood RNA - myeloid DC [nTPM]":"5.5","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.3","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"2.3","Blood RNA - non-classical monocyte [nTPM]":"7.1","Blood RNA - plasmacytoid DC [nTPM]":"2.7","Blood RNA - T-reg [nTPM]":"3.0","Blood RNA - total PBMC [nTPM]":"4.2","Brain RNA - amygdala [nTPM]":"7.4","Brain RNA - basal ganglia [nTPM]":"8.0","Brain RNA - cerebellum [nTPM]":"7.9","Brain RNA - cerebral cortex [nTPM]":"8.4","Brain RNA - hippocampal formation [nTPM]":"7.2","Brain RNA - hypothalamus [nTPM]":"10.5","Brain RNA - medulla oblongata [nTPM]":"10.4","Brain RNA - midbrain [nTPM]":"8.5","Brain RNA - pons [nTPM]":"10.1","Brain RNA - spinal cord [nTPM]":"9.0","Brain RNA - thalamus [nTPM]":"9.1","Brain RNA - white matter [nTPM]":"9.3","Single Cell Type RNA - Adipocytes [nTPM]":"65.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.8","Single Cell Type RNA - Astrocytes [nTPM]":"54.9","Single Cell Type RNA - B-cells [nTPM]":"10.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"27.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.3","Single Cell Type RNA - Bipolar cells [nTPM]":"1.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"23.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"21.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"34.0","Single Cell Type RNA - dendritic cells [nTPM]":"14.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"38.4","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"32.1","Single Cell Type RNA - Endothelial cells [nTPM]":"37.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"8.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"49.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"37.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"28.0","Single Cell Type RNA - Fibroblasts [nTPM]":"44.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.0","Single Cell Type RNA - granulocytes [nTPM]":"12.7","Single Cell Type RNA - Granulosa cells [nTPM]":"20.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"52.5","Single Cell Type RNA - Hepatocytes [nTPM]":"88.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"49.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.5","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"56.3","Single Cell Type RNA - Langerhans cells [nTPM]":"22.9","Single Cell Type RNA - Late spermatids [nTPM]":"3.5","Single Cell Type RNA - Leydig cells [nTPM]":"51.3","Single Cell Type RNA - Macrophages [nTPM]":"46.0","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"68.4","Single Cell Type RNA - monocytes [nTPM]":"29.1","Single Cell Type RNA - Muller glia cells [nTPM]":"8.2","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"110.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"73.3","Single Cell Type RNA - Paneth cells [nTPM]":"10.0","Single Cell Type RNA - Peritubular cells [nTPM]":"40.6","Single Cell Type RNA - Plasma cells [nTPM]":"12.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"29.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"70.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"45.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"52.1","Single Cell Type RNA - Spermatocytes [nTPM]":"3.5","Single Cell Type RNA - Spermatogonia [nTPM]":"4.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"24.6","Single Cell Type RNA - T-cells [nTPM]":"17.3","Single Cell Type RNA - Theca cells [nTPM]":"6.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.6","Single Cell Type RNA - Urothelial cells [nTPM]":"30.5"},{"Gene":"ANXA11","Gene synonym":["ANX11"],"Ensembl":"ENSG00000122359","Gene description":"Annexin A11","Uniprot":["P50995"],"Chromosome":"10","Position":"80150889-80205572","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Cell cycle","Cell division"],"Molecular function":null,"Disease involvement":["Amyotrophic lateral sclerosis","Cancer-related genes","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"443.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004851","HPA027545"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"210000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB004851":"AB_626682","HPA027545":"AB_1844851"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.18e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.69e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Tissue RNA - adipose tissue [nTPM]":"139.9","Tissue RNA - adrenal gland [nTPM]":"29.5","Tissue RNA - amygdala [nTPM]":"39.0","Tissue RNA - appendix [nTPM]":"99.4","Tissue RNA - basal ganglia [nTPM]":"40.6","Tissue RNA - bone marrow [nTPM]":"192.9","Tissue RNA - breast [nTPM]":"107.6","Tissue RNA - cerebellum [nTPM]":"27.5","Tissue RNA - cerebral cortex [nTPM]":"46.8","Tissue RNA - cervix [nTPM]":"86.6","Tissue RNA - choroid plexus [nTPM]":"52.8","Tissue RNA - colon [nTPM]":"130.3","Tissue RNA - duodenum [nTPM]":"138.0","Tissue RNA - endometrium 1 [nTPM]":"74.3","Tissue RNA - epididymis [nTPM]":"107.5","Tissue RNA - esophagus [nTPM]":"210.2","Tissue RNA - fallopian tube [nTPM]":"109.0","Tissue RNA - gallbladder [nTPM]":"84.8","Tissue RNA - heart muscle [nTPM]":"236.2","Tissue RNA - hippocampal formation [nTPM]":"47.3","Tissue RNA - hypothalamus [nTPM]":"29.0","Tissue RNA - kidney [nTPM]":"144.7","Tissue RNA - liver [nTPM]":"47.7","Tissue RNA - lung [nTPM]":"109.5","Tissue RNA - lymph node [nTPM]":"81.2","Tissue RNA - medulla oblongata [nTPM]":"26.4","Tissue RNA - midbrain [nTPM]":"26.6","Tissue RNA - ovary [nTPM]":"78.2","Tissue RNA - pancreas [nTPM]":"95.4","Tissue RNA - parathyroid gland [nTPM]":"81.8","Tissue RNA - pituitary gland [nTPM]":"27.2","Tissue RNA - placenta [nTPM]":"91.1","Tissue RNA - pons [nTPM]":"23.9","Tissue RNA - prostate [nTPM]":"100.3","Tissue RNA - rectum [nTPM]":"120.7","Tissue RNA - retina [nTPM]":"4.8","Tissue RNA - salivary gland [nTPM]":"94.1","Tissue RNA - seminal vesicle [nTPM]":"81.8","Tissue RNA - skeletal muscle [nTPM]":"188.9","Tissue RNA - skin 1 [nTPM]":"75.6","Tissue RNA - small intestine [nTPM]":"137.2","Tissue RNA - smooth muscle [nTPM]":"86.0","Tissue RNA - spinal cord [nTPM]":"25.4","Tissue RNA - spleen [nTPM]":"76.2","Tissue RNA - stomach 1 [nTPM]":"139.3","Tissue RNA - testis [nTPM]":"24.5","Tissue RNA - thalamus [nTPM]":"24.6","Tissue RNA - thymus [nTPM]":"100.2","Tissue RNA - thyroid gland [nTPM]":"61.4","Tissue RNA - tongue [nTPM]":"166.2","Tissue RNA - tonsil [nTPM]":"101.7","Tissue RNA - urinary bladder [nTPM]":"148.1","Tissue RNA - vagina [nTPM]":"102.8","Tissue RNA - white matter [nTPM]":"30.4","Cell RNA - A-431 [nTPM]":"221.7","Cell RNA - A549 [nTPM]":"195.7","Cell RNA - AF22 [nTPM]":"10.4","Cell RNA - AN3-CA [nTPM]":"53.9","Cell RNA - ASC diff [nTPM]":"220.2","Cell RNA - ASC TERT1 [nTPM]":"201.1","Cell RNA - BEWO [nTPM]":"119.6","Cell RNA - BJ [nTPM]":"149.5","Cell RNA - BJ hTERT+ [nTPM]":"397.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"95.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"98.8","Cell RNA - CACO-2 [nTPM]":"168.7","Cell RNA - CAPAN-2 [nTPM]":"338.2","Cell RNA - Daudi [nTPM]":"13.1","Cell RNA - EFO-21 [nTPM]":"113.6","Cell RNA - fHDF\/TERT166 [nTPM]":"236.7","Cell RNA - GAMG [nTPM]":"8.1","Cell RNA - HaCaT [nTPM]":"277.7","Cell RNA - HAP1 [nTPM]":"44.6","Cell RNA - HBEC3-KT [nTPM]":"136.2","Cell RNA - HBF TERT88 [nTPM]":"54.2","Cell RNA - HDLM-2 [nTPM]":"384.3","Cell RNA - HEK 293 [nTPM]":"76.0","Cell RNA - HEL [nTPM]":"84.4","Cell RNA - HeLa [nTPM]":"98.9","Cell RNA - Hep G2 [nTPM]":"131.5","Cell RNA - HHSteC [nTPM]":"129.4","Cell RNA - HL-60 [nTPM]":"92.0","Cell RNA - HMC-1 [nTPM]":"212.3","Cell RNA - HSkMC [nTPM]":"222.9","Cell RNA - hTCEpi [nTPM]":"74.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"57.8","Cell RNA - hTERT-HME1 [nTPM]":"39.4","Cell RNA - hTERT-RPE1 [nTPM]":"178.9","Cell RNA - HUVEC TERT2 [nTPM]":"143.9","Cell RNA - JURKAT [nTPM]":"117.9","Cell RNA - K-562 [nTPM]":"82.1","Cell RNA - Karpas-707 [nTPM]":"163.7","Cell RNA - LHCN-M2 [nTPM]":"76.8","Cell RNA - MCF7 [nTPM]":"127.3","Cell RNA - MOLT-4 [nTPM]":"119.8","Cell RNA - NB-4 [nTPM]":"200.9","Cell RNA - NTERA-2 [nTPM]":"19.6","Cell RNA - OE19 [nTPM]":"211.5","Cell RNA - PC-3 [nTPM]":"367.7","Cell RNA - REH [nTPM]":"91.7","Cell RNA - RH-30 [nTPM]":"14.9","Cell RNA - RPMI-8226 [nTPM]":"344.0","Cell RNA - RPTEC TERT1 [nTPM]":"155.1","Cell RNA - RT4 [nTPM]":"191.8","Cell RNA - SCLC-21H [nTPM]":"5.1","Cell RNA - SH-SY5Y [nTPM]":"37.9","Cell RNA - SiHa [nTPM]":"65.0","Cell RNA - SK-BR-3 [nTPM]":"269.9","Cell RNA - SK-MEL-30 [nTPM]":"156.4","Cell RNA - SuSa [nTPM]":"83.4","Cell RNA - T-47d [nTPM]":"80.6","Cell RNA - THP-1 [nTPM]":"120.6","Cell RNA - TIME [nTPM]":"160.0","Cell RNA - U-138 MG [nTPM]":"68.7","Cell RNA - U-2 OS [nTPM]":"101.4","Cell RNA - U-2197 [nTPM]":"157.6","Cell RNA - U-251 MG [nTPM]":"84.4","Cell RNA - U-266\/70 [nTPM]":"91.7","Cell RNA - U-266\/84 [nTPM]":"145.6","Cell RNA - U-698 [nTPM]":"96.0","Cell RNA - U-87 MG [nTPM]":"66.6","Cell RNA - U-937 [nTPM]":"155.4","Cell RNA - WM-115 [nTPM]":"47.4","Blood RNA - basophil [nTPM]":"130.8","Blood RNA - classical monocyte [nTPM]":"66.8","Blood RNA - eosinophil [nTPM]":"443.8","Blood RNA - gdT-cell [nTPM]":"72.9","Blood RNA - intermediate monocyte [nTPM]":"52.4","Blood RNA - MAIT T-cell [nTPM]":"75.0","Blood RNA - memory B-cell [nTPM]":"64.9","Blood RNA - memory CD4 T-cell [nTPM]":"92.5","Blood RNA - memory CD8 T-cell [nTPM]":"100.5","Blood RNA - myeloid DC [nTPM]":"49.4","Blood RNA - naive B-cell [nTPM]":"54.2","Blood RNA - naive CD4 T-cell [nTPM]":"83.7","Blood RNA - naive CD8 T-cell [nTPM]":"74.4","Blood RNA - neutrophil [nTPM]":"231.8","Blood RNA - NK-cell [nTPM]":"61.3","Blood RNA - non-classical monocyte [nTPM]":"59.1","Blood RNA - plasmacytoid DC [nTPM]":"78.5","Blood RNA - T-reg [nTPM]":"126.5","Blood RNA - total PBMC [nTPM]":"85.4","Brain RNA - amygdala [nTPM]":"39.0","Brain RNA - basal ganglia [nTPM]":"40.6","Brain RNA - cerebellum [nTPM]":"27.5","Brain RNA - cerebral cortex [nTPM]":"46.8","Brain RNA - hippocampal formation [nTPM]":"47.3","Brain RNA - hypothalamus [nTPM]":"29.0","Brain RNA - medulla oblongata [nTPM]":"26.4","Brain RNA - midbrain [nTPM]":"26.6","Brain RNA - pons [nTPM]":"23.9","Brain RNA - spinal cord [nTPM]":"25.4","Brain RNA - thalamus [nTPM]":"24.6","Brain RNA - white matter [nTPM]":"30.4","Single Cell Type RNA - Adipocytes [nTPM]":"150.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"96.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"78.4","Single Cell Type RNA - Astrocytes [nTPM]":"17.3","Single Cell Type RNA - B-cells [nTPM]":"101.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"51.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"266.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"219.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"92.8","Single Cell Type RNA - Bipolar cells [nTPM]":"1.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"58.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"50.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"293.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"203.0","Single Cell Type RNA - Club cells [nTPM]":"227.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"220.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"271.7","Single Cell Type RNA - dendritic cells [nTPM]":"137.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"457.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"332.6","Single Cell Type RNA - Ductal cells [nTPM]":"429.2","Single Cell Type RNA - Early spermatids [nTPM]":"4.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"180.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"49.7","Single Cell Type RNA - Endothelial cells [nTPM]":"82.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"77.5","Single Cell Type RNA - Erythroid cells [nTPM]":"29.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"29.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"352.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"309.8","Single Cell Type RNA - Fibroblasts [nTPM]":"113.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"175.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"265.7","Single Cell Type RNA - granulocytes [nTPM]":"116.1","Single Cell Type RNA - Granulosa cells [nTPM]":"81.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"91.4","Single Cell Type RNA - Hepatocytes [nTPM]":"40.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"228.1","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"186.9","Single Cell Type RNA - Ionocytes [nTPM]":"97.6","Single Cell Type RNA - Kupffer cells [nTPM]":"149.7","Single Cell Type RNA - Langerhans cells [nTPM]":"167.4","Single Cell Type RNA - Late spermatids [nTPM]":"9.6","Single Cell Type RNA - Leydig cells [nTPM]":"92.9","Single Cell Type RNA - Macrophages [nTPM]":"155.0","Single Cell Type RNA - Melanocytes [nTPM]":"90.7","Single Cell Type RNA - Microglial cells [nTPM]":"24.4","Single Cell Type RNA - monocytes [nTPM]":"208.2","Single Cell Type RNA - Muller glia cells [nTPM]":"38.9","Single Cell Type RNA - NK-cells [nTPM]":"159.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"420.6","Single Cell Type RNA - Paneth cells [nTPM]":"461.0","Single Cell Type RNA - Peritubular cells [nTPM]":"92.6","Single Cell Type RNA - Plasma cells [nTPM]":"98.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"414.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"367.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"156.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"229.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.8","Single Cell Type RNA - Sertoli cells [nTPM]":"92.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"56.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"137.9","Single Cell Type RNA - Spermatocytes [nTPM]":"2.8","Single Cell Type RNA - Spermatogonia [nTPM]":"51.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"98.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"42.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"185.5","Single Cell Type RNA - T-cells [nTPM]":"131.9","Single Cell Type RNA - Theca cells [nTPM]":"50.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"227.8","Single Cell Type RNA - Urothelial cells [nTPM]":"581.4"},{"Gene":"AP000812.4","Gene synonym":[],"Ensembl":"ENSG00000284922","Gene description":"Leucine rich transmembrane and O-methyltransferase domain containing","Uniprot":["Q8WZ04"],"Chromosome":"11","Position":"72080331-72110782","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Catecholamine metabolism","Hearing","Neurotransmitter degradation"],"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"fallopian tube":"14.1","testis":"9.5"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"fHDF\/TERT166":"2.9","HBEC3-KT":"2.9","MCF7":"3.0"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039949"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":null,"Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA039949":"AB_10960708"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"1.8","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.9","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"14.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.6","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.5","Tissue RNA - pituitary gland [nTPM]":null,"Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"9.5","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":null,"Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.7","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.4","Cell RNA - BJ hTERT+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.2","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"2.9","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"0.6","Cell RNA - HAP1 [nTPM]":"0.4","Cell RNA - HBEC3-KT [nTPM]":"2.9","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"1.2","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"0.5","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.8","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.3","Cell RNA - hTERT-HME1 [nTPM]":"0.4","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.6","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"3.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"1.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.6","Cell RNA - RH-30 [nTPM]":"0.5","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.9","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.4","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.9","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"1.8","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"AP1B1","Gene synonym":["ADTB1","AP105A","BAM22","CLAPB2"],"Ensembl":"ENSG00000100280","Gene description":"Adaptor related protein complex 1 subunit beta 1","Uniprot":["Q10567"],"Chromosome":"22","Position":"29327680-29388583","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"138.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065226","HPA068520"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"660000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"HPA065226":"AB_2685438","HPA068520":"AB_2685998"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.81e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.55e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.24e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Tissue RNA - adipose tissue [nTPM]":"30.7","Tissue RNA - adrenal gland [nTPM]":"46.7","Tissue RNA - amygdala [nTPM]":"38.0","Tissue RNA - appendix [nTPM]":"47.2","Tissue RNA - basal ganglia [nTPM]":"38.3","Tissue RNA - bone marrow [nTPM]":"45.8","Tissue RNA - breast [nTPM]":"26.4","Tissue RNA - cerebellum [nTPM]":"37.3","Tissue RNA - cerebral cortex [nTPM]":"45.2","Tissue RNA - cervix [nTPM]":"22.8","Tissue RNA - choroid plexus [nTPM]":"35.6","Tissue RNA - colon [nTPM]":"34.9","Tissue RNA - duodenum [nTPM]":"43.3","Tissue RNA - endometrium 1 [nTPM]":"22.7","Tissue RNA - epididymis [nTPM]":"12.1","Tissue RNA - esophagus [nTPM]":"63.0","Tissue RNA - fallopian tube [nTPM]":"23.5","Tissue RNA - gallbladder [nTPM]":"30.4","Tissue RNA - heart muscle [nTPM]":"23.9","Tissue RNA - hippocampal formation [nTPM]":"36.1","Tissue RNA - hypothalamus [nTPM]":"40.8","Tissue RNA - kidney [nTPM]":"34.8","Tissue RNA - liver [nTPM]":"34.8","Tissue RNA - lung [nTPM]":"30.1","Tissue RNA - lymph node [nTPM]":"57.8","Tissue RNA - medulla oblongata [nTPM]":"44.2","Tissue RNA - midbrain [nTPM]":"44.6","Tissue RNA - ovary [nTPM]":"17.5","Tissue RNA - pancreas [nTPM]":"38.3","Tissue RNA - parathyroid gland [nTPM]":"67.0","Tissue RNA - pituitary gland [nTPM]":"39.2","Tissue RNA - placenta [nTPM]":"44.8","Tissue RNA - pons [nTPM]":"43.7","Tissue RNA - prostate [nTPM]":"38.3","Tissue RNA - rectum [nTPM]":"30.1","Tissue RNA - retina [nTPM]":"35.3","Tissue RNA - salivary gland [nTPM]":"40.3","Tissue RNA - seminal vesicle [nTPM]":"25.9","Tissue RNA - skeletal muscle [nTPM]":"24.5","Tissue RNA - skin 1 [nTPM]":"47.2","Tissue RNA - small intestine [nTPM]":"45.6","Tissue RNA - smooth muscle [nTPM]":"27.1","Tissue RNA - spinal cord [nTPM]":"41.4","Tissue RNA - spleen [nTPM]":"52.6","Tissue RNA - stomach 1 [nTPM]":"40.9","Tissue RNA - testis [nTPM]":"24.7","Tissue RNA - thalamus [nTPM]":"52.7","Tissue RNA - thymus [nTPM]":"34.2","Tissue RNA - thyroid gland [nTPM]":"29.6","Tissue RNA - tongue [nTPM]":"20.5","Tissue RNA - tonsil [nTPM]":"54.4","Tissue RNA - urinary bladder [nTPM]":"39.4","Tissue RNA - vagina [nTPM]":"32.2","Tissue RNA - white matter [nTPM]":"48.8","Cell RNA - A-431 [nTPM]":"84.6","Cell RNA - A549 [nTPM]":"47.5","Cell RNA - AF22 [nTPM]":"49.3","Cell RNA - AN3-CA [nTPM]":"50.2","Cell RNA - ASC diff [nTPM]":"37.0","Cell RNA - ASC TERT1 [nTPM]":"27.0","Cell RNA - BEWO [nTPM]":"60.0","Cell RNA - BJ [nTPM]":"59.8","Cell RNA - BJ hTERT+ [nTPM]":"65.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"71.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"68.2","Cell RNA - CACO-2 [nTPM]":"74.4","Cell RNA - CAPAN-2 [nTPM]":"33.2","Cell RNA - Daudi [nTPM]":"46.1","Cell RNA - EFO-21 [nTPM]":"37.2","Cell RNA - fHDF\/TERT166 [nTPM]":"68.4","Cell RNA - GAMG [nTPM]":"33.0","Cell RNA - HaCaT [nTPM]":"74.6","Cell RNA - HAP1 [nTPM]":"71.5","Cell RNA - HBEC3-KT [nTPM]":"97.6","Cell RNA - HBF TERT88 [nTPM]":"45.2","Cell RNA - HDLM-2 [nTPM]":"58.2","Cell RNA - HEK 293 [nTPM]":"102.0","Cell RNA - HEL [nTPM]":"79.1","Cell RNA - HeLa [nTPM]":"60.8","Cell RNA - Hep G2 [nTPM]":"42.0","Cell RNA - HHSteC [nTPM]":"38.9","Cell RNA - HL-60 [nTPM]":"114.1","Cell RNA - HMC-1 [nTPM]":"99.9","Cell RNA - HSkMC [nTPM]":"38.6","Cell RNA - hTCEpi [nTPM]":"36.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"67.5","Cell RNA - hTERT-HME1 [nTPM]":"55.0","Cell RNA - hTERT-RPE1 [nTPM]":"33.0","Cell RNA - HUVEC TERT2 [nTPM]":"98.7","Cell RNA - JURKAT [nTPM]":"17.2","Cell RNA - K-562 [nTPM]":"54.6","Cell RNA - Karpas-707 [nTPM]":"54.9","Cell RNA - LHCN-M2 [nTPM]":"48.3","Cell RNA - MCF7 [nTPM]":"93.7","Cell RNA - MOLT-4 [nTPM]":"45.5","Cell RNA - NB-4 [nTPM]":"36.8","Cell RNA - NTERA-2 [nTPM]":"37.3","Cell RNA - OE19 [nTPM]":"124.8","Cell RNA - PC-3 [nTPM]":"53.3","Cell RNA - REH [nTPM]":"89.0","Cell RNA - RH-30 [nTPM]":"54.3","Cell RNA - RPMI-8226 [nTPM]":"119.9","Cell RNA - RPTEC TERT1 [nTPM]":"50.2","Cell RNA - RT4 [nTPM]":"194.5","Cell RNA - SCLC-21H [nTPM]":"75.9","Cell RNA - SH-SY5Y [nTPM]":"52.2","Cell RNA - SiHa [nTPM]":"74.0","Cell RNA - SK-BR-3 [nTPM]":"82.5","Cell RNA - SK-MEL-30 [nTPM]":"36.4","Cell RNA - SuSa [nTPM]":"33.5","Cell RNA - T-47d [nTPM]":"66.7","Cell RNA - THP-1 [nTPM]":"49.5","Cell RNA - TIME [nTPM]":"84.6","Cell RNA - U-138 MG [nTPM]":"79.1","Cell RNA - U-2 OS [nTPM]":"48.8","Cell RNA - U-2197 [nTPM]":"46.0","Cell RNA - U-251 MG [nTPM]":"62.1","Cell RNA - U-266\/70 [nTPM]":"60.4","Cell RNA - U-266\/84 [nTPM]":"32.5","Cell RNA - U-698 [nTPM]":"84.6","Cell RNA - U-87 MG [nTPM]":"56.1","Cell RNA - U-937 [nTPM]":"48.1","Cell RNA - WM-115 [nTPM]":"46.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"29.3","Blood RNA - eosinophil [nTPM]":"5.7","Blood RNA - gdT-cell [nTPM]":"9.2","Blood RNA - intermediate monocyte [nTPM]":"29.2","Blood RNA - MAIT T-cell [nTPM]":"9.1","Blood RNA - memory B-cell [nTPM]":"16.2","Blood RNA - memory CD4 T-cell [nTPM]":"6.3","Blood RNA - memory CD8 T-cell [nTPM]":"7.9","Blood RNA - myeloid DC [nTPM]":"28.7","Blood RNA - naive B-cell [nTPM]":"18.2","Blood RNA - naive CD4 T-cell [nTPM]":"4.9","Blood RNA - naive CD8 T-cell [nTPM]":"5.2","Blood RNA - neutrophil [nTPM]":"3.0","Blood RNA - NK-cell [nTPM]":"7.2","Blood RNA - non-classical monocyte [nTPM]":"31.7","Blood RNA - plasmacytoid DC [nTPM]":"9.0","Blood RNA - T-reg [nTPM]":"8.8","Blood RNA - total PBMC [nTPM]":"24.2","Brain RNA - amygdala [nTPM]":"38.0","Brain RNA - basal ganglia [nTPM]":"38.3","Brain RNA - cerebellum [nTPM]":"37.3","Brain RNA - cerebral cortex [nTPM]":"45.2","Brain RNA - hippocampal formation [nTPM]":"36.1","Brain RNA - hypothalamus [nTPM]":"40.8","Brain RNA - medulla oblongata [nTPM]":"44.2","Brain RNA - midbrain [nTPM]":"44.6","Brain RNA - pons [nTPM]":"43.7","Brain RNA - spinal cord [nTPM]":"41.4","Brain RNA - thalamus [nTPM]":"52.7","Brain RNA - white matter [nTPM]":"48.8","Single Cell Type RNA - Adipocytes [nTPM]":"17.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.4","Single Cell Type RNA - Astrocytes [nTPM]":"27.7","Single Cell Type RNA - B-cells [nTPM]":"53.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"16.5","Single Cell Type RNA - Bipolar cells [nTPM]":"26.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"16.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"52.3","Single Cell Type RNA - dendritic cells [nTPM]":"15.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"69.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"41.2","Single Cell Type RNA - Early spermatids [nTPM]":"7.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.6","Single Cell Type RNA - Endothelial cells [nTPM]":"19.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.6","Single Cell Type RNA - Erythroid cells [nTPM]":"40.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"24.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"40.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"30.1","Single Cell Type RNA - Fibroblasts [nTPM]":"12.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"33.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"30.1","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"13.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"35.3","Single Cell Type RNA - Hepatocytes [nTPM]":"34.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"138.9","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.9","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"95.5","Single Cell Type RNA - Langerhans cells [nTPM]":"24.2","Single Cell Type RNA - Late spermatids [nTPM]":"13.1","Single Cell Type RNA - Leydig cells [nTPM]":"11.8","Single Cell Type RNA - Macrophages [nTPM]":"65.7","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"51.5","Single Cell Type RNA - monocytes [nTPM]":"29.8","Single Cell Type RNA - Muller glia cells [nTPM]":"28.4","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"65.9","Single Cell Type RNA - Paneth cells [nTPM]":"33.2","Single Cell Type RNA - Peritubular cells [nTPM]":"12.4","Single Cell Type RNA - Plasma cells [nTPM]":"28.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"51.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"30.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"42.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.7","Single Cell Type RNA - Spermatocytes [nTPM]":"23.5","Single Cell Type RNA - Spermatogonia [nTPM]":"17.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"33.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"68.3","Single Cell Type RNA - T-cells [nTPM]":"17.0","Single Cell Type RNA - Theca cells [nTPM]":"39.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"36.2","Single Cell Type RNA - Urothelial cells [nTPM]":"18.1"},{"Gene":"AP1S1","Gene synonym":["AP19","CLAPS1","EKV3","SIGMA1A","WUGSC:H_DJ0747G18.2"],"Ensembl":"ENSG00000106367","Gene description":"Adaptor related protein complex 1 subunit sigma 1","Uniprot":["P61966"],"Chromosome":"7","Position":"101154456-101161596","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Deafness","Ichthyosis","Mental retardation","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"344.4","Proximal enterocytes":"241.3","Proximal tubular cells":"304.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060945"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA060945":"AB_2684393"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.70e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Tissue RNA - adipose tissue [nTPM]":"14.4","Tissue RNA - adrenal gland [nTPM]":"24.6","Tissue RNA - amygdala [nTPM]":"72.2","Tissue RNA - appendix [nTPM]":"13.9","Tissue RNA - basal ganglia [nTPM]":"75.7","Tissue RNA - bone marrow [nTPM]":"5.8","Tissue RNA - breast [nTPM]":"17.2","Tissue RNA - cerebellum [nTPM]":"43.7","Tissue RNA - cerebral cortex [nTPM]":"82.6","Tissue RNA - cervix [nTPM]":"18.3","Tissue RNA - choroid plexus [nTPM]":"34.6","Tissue RNA - colon [nTPM]":"28.6","Tissue RNA - duodenum [nTPM]":"39.0","Tissue RNA - endometrium 1 [nTPM]":"16.9","Tissue RNA - epididymis [nTPM]":"17.0","Tissue RNA - esophagus [nTPM]":"34.2","Tissue RNA - fallopian tube [nTPM]":"13.8","Tissue RNA - gallbladder [nTPM]":"12.8","Tissue RNA - heart muscle [nTPM]":"11.8","Tissue RNA - hippocampal formation [nTPM]":"85.2","Tissue RNA - hypothalamus [nTPM]":"59.6","Tissue RNA - kidney [nTPM]":"41.2","Tissue RNA - liver [nTPM]":"36.2","Tissue RNA - lung [nTPM]":"14.7","Tissue RNA - lymph node [nTPM]":"11.9","Tissue RNA - medulla oblongata [nTPM]":"53.6","Tissue RNA - midbrain [nTPM]":"51.9","Tissue RNA - ovary [nTPM]":"13.5","Tissue RNA - pancreas [nTPM]":"21.9","Tissue RNA - parathyroid gland [nTPM]":"22.8","Tissue RNA - pituitary gland [nTPM]":"31.0","Tissue RNA - placenta [nTPM]":"15.9","Tissue RNA - pons [nTPM]":"53.4","Tissue RNA - prostate [nTPM]":"22.2","Tissue RNA - rectum [nTPM]":"22.4","Tissue RNA - retina [nTPM]":"14.6","Tissue RNA - salivary gland [nTPM]":"20.3","Tissue RNA - seminal vesicle [nTPM]":"9.3","Tissue RNA - skeletal muscle [nTPM]":"6.4","Tissue RNA - skin 1 [nTPM]":"39.2","Tissue RNA - small intestine [nTPM]":"30.3","Tissue RNA - smooth muscle [nTPM]":"12.7","Tissue RNA - spinal cord [nTPM]":"46.1","Tissue RNA - spleen [nTPM]":"20.2","Tissue RNA - stomach 1 [nTPM]":"22.0","Tissue RNA - testis [nTPM]":"16.4","Tissue RNA - thalamus [nTPM]":"62.5","Tissue RNA - thymus [nTPM]":"19.1","Tissue RNA - thyroid gland [nTPM]":"15.2","Tissue RNA - tongue [nTPM]":"8.5","Tissue RNA - tonsil [nTPM]":"13.6","Tissue RNA - urinary bladder [nTPM]":"20.1","Tissue RNA - vagina [nTPM]":"19.5","Tissue RNA - white matter [nTPM]":"62.7","Cell RNA - A-431 [nTPM]":"121.0","Cell RNA - A549 [nTPM]":"87.3","Cell RNA - AF22 [nTPM]":"63.3","Cell RNA - AN3-CA [nTPM]":"118.4","Cell RNA - ASC diff [nTPM]":"42.8","Cell RNA - ASC TERT1 [nTPM]":"70.4","Cell RNA - BEWO [nTPM]":"138.2","Cell RNA - BJ [nTPM]":"76.8","Cell RNA - BJ hTERT+ [nTPM]":"51.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"50.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"52.8","Cell RNA - CACO-2 [nTPM]":"47.3","Cell RNA - CAPAN-2 [nTPM]":"147.5","Cell RNA - Daudi [nTPM]":"24.9","Cell RNA - EFO-21 [nTPM]":"127.5","Cell RNA - fHDF\/TERT166 [nTPM]":"84.6","Cell RNA - GAMG [nTPM]":"97.1","Cell RNA - HaCaT [nTPM]":"59.0","Cell RNA - HAP1 [nTPM]":"35.3","Cell RNA - HBEC3-KT [nTPM]":"116.0","Cell RNA - HBF TERT88 [nTPM]":"45.6","Cell RNA - HDLM-2 [nTPM]":"57.0","Cell RNA - HEK 293 [nTPM]":"56.6","Cell RNA - HEL [nTPM]":"16.8","Cell RNA - HeLa [nTPM]":"52.0","Cell RNA - Hep G2 [nTPM]":"61.4","Cell RNA - HHSteC [nTPM]":"54.2","Cell RNA - HL-60 [nTPM]":"46.8","Cell RNA - HMC-1 [nTPM]":"87.7","Cell RNA - HSkMC [nTPM]":"79.1","Cell RNA - hTCEpi [nTPM]":"91.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"49.4","Cell RNA - hTERT-HME1 [nTPM]":"20.6","Cell RNA - hTERT-RPE1 [nTPM]":"76.7","Cell RNA - HUVEC TERT2 [nTPM]":"76.8","Cell RNA - JURKAT [nTPM]":"54.1","Cell RNA - K-562 [nTPM]":"56.7","Cell RNA - Karpas-707 [nTPM]":"103.2","Cell RNA - LHCN-M2 [nTPM]":"129.9","Cell RNA - MCF7 [nTPM]":"292.1","Cell RNA - MOLT-4 [nTPM]":"40.4","Cell RNA - NB-4 [nTPM]":"107.8","Cell RNA - NTERA-2 [nTPM]":"97.8","Cell RNA - OE19 [nTPM]":"177.0","Cell RNA - PC-3 [nTPM]":"188.2","Cell RNA - REH [nTPM]":"24.9","Cell RNA - RH-30 [nTPM]":"27.2","Cell RNA - RPMI-8226 [nTPM]":"54.6","Cell RNA - RPTEC TERT1 [nTPM]":"127.8","Cell RNA - RT4 [nTPM]":"88.8","Cell RNA - SCLC-21H [nTPM]":"47.5","Cell RNA - SH-SY5Y [nTPM]":"157.7","Cell RNA - SiHa [nTPM]":"40.4","Cell RNA - SK-BR-3 [nTPM]":"121.1","Cell RNA - SK-MEL-30 [nTPM]":"151.4","Cell RNA - SuSa [nTPM]":"101.6","Cell RNA - T-47d [nTPM]":"50.7","Cell RNA - THP-1 [nTPM]":"46.8","Cell RNA - TIME [nTPM]":"79.0","Cell RNA - U-138 MG [nTPM]":"74.1","Cell RNA - U-2 OS [nTPM]":"132.3","Cell RNA - U-2197 [nTPM]":"27.6","Cell RNA - U-251 MG [nTPM]":"55.2","Cell RNA - U-266\/70 [nTPM]":"21.4","Cell RNA - U-266\/84 [nTPM]":"51.4","Cell RNA - U-698 [nTPM]":"48.4","Cell RNA - U-87 MG [nTPM]":"195.2","Cell RNA - U-937 [nTPM]":"50.1","Cell RNA - WM-115 [nTPM]":"152.9","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"3.3","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"2.3","Blood RNA - intermediate monocyte [nTPM]":"3.1","Blood RNA - MAIT T-cell [nTPM]":"2.2","Blood RNA - memory B-cell [nTPM]":"2.6","Blood RNA - memory CD4 T-cell [nTPM]":"3.2","Blood RNA - memory CD8 T-cell [nTPM]":"2.5","Blood RNA - myeloid DC [nTPM]":"4.6","Blood RNA - naive B-cell [nTPM]":"2.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.9","Blood RNA - naive CD8 T-cell [nTPM]":"1.8","Blood RNA - neutrophil [nTPM]":"1.2","Blood RNA - NK-cell [nTPM]":"1.3","Blood RNA - non-classical monocyte [nTPM]":"1.8","Blood RNA - plasmacytoid DC [nTPM]":"5.0","Blood RNA - T-reg [nTPM]":"3.3","Blood RNA - total PBMC [nTPM]":"2.4","Brain RNA - amygdala [nTPM]":"72.2","Brain RNA - basal ganglia [nTPM]":"75.7","Brain RNA - cerebellum [nTPM]":"43.7","Brain RNA - cerebral cortex [nTPM]":"82.6","Brain RNA - hippocampal formation [nTPM]":"85.2","Brain RNA - hypothalamus [nTPM]":"59.6","Brain RNA - medulla oblongata [nTPM]":"53.6","Brain RNA - midbrain [nTPM]":"51.9","Brain RNA - pons [nTPM]":"53.4","Brain RNA - spinal cord [nTPM]":"46.1","Brain RNA - thalamus [nTPM]":"62.5","Brain RNA - white matter [nTPM]":"62.7","Single Cell Type RNA - Adipocytes [nTPM]":"34.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.3","Single Cell Type RNA - B-cells [nTPM]":"17.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"38.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"29.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"173.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"46.7","Single Cell Type RNA - Bipolar cells [nTPM]":"30.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"54.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"49.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"45.8","Single Cell Type RNA - Club cells [nTPM]":"72.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"55.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"170.7","Single Cell Type RNA - dendritic cells [nTPM]":"19.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"88.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"344.4","Single Cell Type RNA - Ductal cells [nTPM]":"128.2","Single Cell Type RNA - Early spermatids [nTPM]":"2.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"28.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"34.2","Single Cell Type RNA - Endothelial cells [nTPM]":"36.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"90.3","Single Cell Type RNA - Erythroid cells [nTPM]":"16.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"21.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"111.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"101.3","Single Cell Type RNA - Fibroblasts [nTPM]":"27.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"42.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"31.9","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"85.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.9","Single Cell Type RNA - Hepatocytes [nTPM]":"43.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"95.2","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"96.5","Single Cell Type RNA - Ionocytes [nTPM]":"116.0","Single Cell Type RNA - Kupffer cells [nTPM]":"24.8","Single Cell Type RNA - Langerhans cells [nTPM]":"21.6","Single Cell Type RNA - Late spermatids [nTPM]":"3.4","Single Cell Type RNA - Leydig cells [nTPM]":"35.1","Single Cell Type RNA - Macrophages [nTPM]":"27.3","Single Cell Type RNA - Melanocytes [nTPM]":"53.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"58.0","Single Cell Type RNA - Muller glia cells [nTPM]":"34.1","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"183.3","Single Cell Type RNA - Paneth cells [nTPM]":"86.1","Single Cell Type RNA - Peritubular cells [nTPM]":"21.8","Single Cell Type RNA - Plasma cells [nTPM]":"17.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"34.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"241.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"304.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"34.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"22.3","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"38.4","Single Cell Type RNA - Spermatocytes [nTPM]":"13.1","Single Cell Type RNA - Spermatogonia [nTPM]":"70.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"51.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"45.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"60.5","Single Cell Type RNA - T-cells [nTPM]":"19.5","Single Cell Type RNA - Theca cells [nTPM]":"157.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"119.9","Single Cell Type RNA - Urothelial cells [nTPM]":"38.2"},{"Gene":"AP2M1","Gene synonym":["AP50","CLAPM1","mu2"],"Ensembl":"ENSG00000161203","Gene description":"Adaptor related protein complex 2 subunit mu 1","Uniprot":["Q96CW1"],"Chromosome":"3","Position":"184174689-184184091","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Endocytosis","Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036849","HPA069870"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7500","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA036849":"AB_10672101","HPA069870":"AB_2686217"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.12e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.45e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Tissue RNA - adipose tissue [nTPM]":"191.8","Tissue RNA - adrenal gland [nTPM]":"364.2","Tissue RNA - amygdala [nTPM]":"233.5","Tissue RNA - appendix [nTPM]":"164.7","Tissue RNA - basal ganglia [nTPM]":"250.3","Tissue RNA - bone marrow [nTPM]":"231.3","Tissue RNA - breast [nTPM]":"164.6","Tissue RNA - cerebellum [nTPM]":"211.3","Tissue RNA - cerebral cortex [nTPM]":"257.3","Tissue RNA - cervix [nTPM]":"222.8","Tissue RNA - choroid plexus [nTPM]":"196.3","Tissue RNA - colon [nTPM]":"232.4","Tissue RNA - duodenum [nTPM]":"167.5","Tissue RNA - endometrium 1 [nTPM]":"216.4","Tissue RNA - epididymis [nTPM]":"104.2","Tissue RNA - esophagus [nTPM]":"218.1","Tissue RNA - fallopian tube [nTPM]":"178.6","Tissue RNA - gallbladder [nTPM]":"166.5","Tissue RNA - heart muscle [nTPM]":"366.2","Tissue RNA - hippocampal formation [nTPM]":"261.1","Tissue RNA - hypothalamus [nTPM]":"249.0","Tissue RNA - kidney [nTPM]":"196.0","Tissue RNA - liver [nTPM]":"140.9","Tissue RNA - lung [nTPM]":"180.0","Tissue RNA - lymph node [nTPM]":"148.2","Tissue RNA - medulla oblongata [nTPM]":"234.8","Tissue RNA - midbrain [nTPM]":"211.1","Tissue RNA - ovary [nTPM]":"198.6","Tissue RNA - pancreas [nTPM]":"106.4","Tissue RNA - parathyroid gland [nTPM]":"224.8","Tissue RNA - pituitary gland [nTPM]":"224.9","Tissue RNA - placenta [nTPM]":"243.3","Tissue RNA - pons [nTPM]":"248.9","Tissue RNA - prostate [nTPM]":"183.2","Tissue RNA - rectum [nTPM]":"141.1","Tissue RNA - retina [nTPM]":"230.4","Tissue RNA - salivary gland [nTPM]":"167.2","Tissue RNA - seminal vesicle [nTPM]":"231.8","Tissue RNA - skeletal muscle [nTPM]":"181.2","Tissue RNA - skin 1 [nTPM]":"157.2","Tissue RNA - small intestine [nTPM]":"156.2","Tissue RNA - smooth muscle [nTPM]":"243.7","Tissue RNA - spinal cord [nTPM]":"200.9","Tissue RNA - spleen [nTPM]":"162.5","Tissue RNA - stomach 1 [nTPM]":"156.3","Tissue RNA - testis [nTPM]":"106.4","Tissue RNA - thalamus [nTPM]":"235.4","Tissue RNA - thymus [nTPM]":"158.4","Tissue RNA - thyroid gland [nTPM]":"148.0","Tissue RNA - tongue [nTPM]":"194.0","Tissue RNA - tonsil [nTPM]":"157.6","Tissue RNA - urinary bladder [nTPM]":"223.7","Tissue RNA - vagina [nTPM]":"192.4","Tissue RNA - white matter [nTPM]":"225.6","Cell RNA - A-431 [nTPM]":"436.3","Cell RNA - A549 [nTPM]":"327.5","Cell RNA - AF22 [nTPM]":"275.7","Cell RNA - AN3-CA [nTPM]":"311.8","Cell RNA - ASC diff [nTPM]":"432.1","Cell RNA - ASC TERT1 [nTPM]":"450.8","Cell RNA - BEWO [nTPM]":"284.3","Cell RNA - BJ [nTPM]":"714.3","Cell RNA - BJ hTERT+ [nTPM]":"412.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"788.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"550.5","Cell RNA - CACO-2 [nTPM]":"355.1","Cell RNA - CAPAN-2 [nTPM]":"309.9","Cell RNA - Daudi [nTPM]":"198.2","Cell RNA - EFO-21 [nTPM]":"851.3","Cell RNA - fHDF\/TERT166 [nTPM]":"1076.1","Cell RNA - GAMG [nTPM]":"516.1","Cell RNA - HaCaT [nTPM]":"480.0","Cell RNA - HAP1 [nTPM]":"376.3","Cell RNA - HBEC3-KT [nTPM]":"482.9","Cell RNA - HBF TERT88 [nTPM]":"647.1","Cell RNA - HDLM-2 [nTPM]":"409.8","Cell RNA - HEK 293 [nTPM]":"470.4","Cell RNA - HEL [nTPM]":"512.2","Cell RNA - HeLa [nTPM]":"365.8","Cell RNA - Hep G2 [nTPM]":"317.9","Cell RNA - HHSteC [nTPM]":"508.9","Cell RNA - HL-60 [nTPM]":"254.8","Cell RNA - HMC-1 [nTPM]":"311.5","Cell RNA - HSkMC [nTPM]":"577.0","Cell RNA - hTCEpi [nTPM]":"269.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"501.1","Cell RNA - hTERT-HME1 [nTPM]":"318.5","Cell RNA - hTERT-RPE1 [nTPM]":"711.0","Cell RNA - HUVEC TERT2 [nTPM]":"595.3","Cell RNA - JURKAT [nTPM]":"258.3","Cell RNA - K-562 [nTPM]":"250.0","Cell RNA - Karpas-707 [nTPM]":"377.1","Cell RNA - LHCN-M2 [nTPM]":"750.1","Cell RNA - MCF7 [nTPM]":"993.6","Cell RNA - MOLT-4 [nTPM]":"330.1","Cell RNA - NB-4 [nTPM]":"151.2","Cell RNA - NTERA-2 [nTPM]":"674.1","Cell RNA - OE19 [nTPM]":"388.1","Cell RNA - PC-3 [nTPM]":"484.7","Cell RNA - REH [nTPM]":"302.7","Cell RNA - RH-30 [nTPM]":"351.5","Cell RNA - RPMI-8226 [nTPM]":"393.7","Cell RNA - RPTEC TERT1 [nTPM]":"489.7","Cell RNA - RT4 [nTPM]":"389.3","Cell RNA - SCLC-21H [nTPM]":"292.0","Cell RNA - SH-SY5Y [nTPM]":"212.6","Cell RNA - SiHa [nTPM]":"561.3","Cell RNA - SK-BR-3 [nTPM]":"696.4","Cell RNA - SK-MEL-30 [nTPM]":"335.1","Cell RNA - SuSa [nTPM]":"427.5","Cell RNA - T-47d [nTPM]":"934.4","Cell RNA - THP-1 [nTPM]":"305.7","Cell RNA - TIME [nTPM]":"645.0","Cell RNA - U-138 MG [nTPM]":"497.1","Cell RNA - U-2 OS [nTPM]":"400.1","Cell RNA - U-2197 [nTPM]":"492.4","Cell RNA - U-251 MG [nTPM]":"960.2","Cell RNA - U-266\/70 [nTPM]":"336.9","Cell RNA - U-266\/84 [nTPM]":"318.7","Cell RNA - U-698 [nTPM]":"441.6","Cell RNA - U-87 MG [nTPM]":"937.1","Cell RNA - U-937 [nTPM]":"369.9","Cell RNA - WM-115 [nTPM]":"331.7","Blood RNA - basophil [nTPM]":"194.4","Blood RNA - classical monocyte [nTPM]":"294.8","Blood RNA - eosinophil [nTPM]":"244.9","Blood RNA - gdT-cell [nTPM]":"137.5","Blood RNA - intermediate monocyte [nTPM]":"238.8","Blood RNA - MAIT T-cell [nTPM]":"136.2","Blood RNA - memory B-cell [nTPM]":"114.3","Blood RNA - memory CD4 T-cell [nTPM]":"127.6","Blood RNA - memory CD8 T-cell [nTPM]":"134.0","Blood RNA - myeloid DC [nTPM]":"268.7","Blood RNA - naive B-cell [nTPM]":"112.7","Blood RNA - naive CD4 T-cell [nTPM]":"107.7","Blood RNA - naive CD8 T-cell [nTPM]":"111.8","Blood RNA - neutrophil [nTPM]":"127.7","Blood RNA - NK-cell [nTPM]":"170.2","Blood RNA - non-classical monocyte [nTPM]":"206.8","Blood RNA - plasmacytoid DC [nTPM]":"134.1","Blood RNA - T-reg [nTPM]":"185.4","Blood RNA - total PBMC [nTPM]":"441.0","Brain RNA - amygdala [nTPM]":"233.5","Brain RNA - basal ganglia [nTPM]":"250.3","Brain RNA - cerebellum [nTPM]":"211.3","Brain RNA - cerebral cortex [nTPM]":"257.3","Brain RNA - hippocampal formation [nTPM]":"261.1","Brain RNA - hypothalamus [nTPM]":"249.0","Brain RNA - medulla oblongata [nTPM]":"234.8","Brain RNA - midbrain [nTPM]":"211.1","Brain RNA - pons [nTPM]":"248.9","Brain RNA - spinal cord [nTPM]":"200.9","Brain RNA - thalamus [nTPM]":"235.4","Brain RNA - white matter [nTPM]":"225.6","Single Cell Type RNA - Adipocytes [nTPM]":"146.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"54.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"50.7","Single Cell Type RNA - Astrocytes [nTPM]":"41.4","Single Cell Type RNA - B-cells [nTPM]":"84.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"124.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"177.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"275.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"97.9","Single Cell Type RNA - Bipolar cells [nTPM]":"174.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"108.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"98.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"195.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"112.9","Single Cell Type RNA - Club cells [nTPM]":"133.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"114.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"70.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"400.9","Single Cell Type RNA - dendritic cells [nTPM]":"117.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"155.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"375.6","Single Cell Type RNA - Ductal cells [nTPM]":"243.7","Single Cell Type RNA - Early spermatids [nTPM]":"326.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"69.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"131.2","Single Cell Type RNA - Endothelial cells [nTPM]":"172.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"140.8","Single Cell Type RNA - Erythroid cells [nTPM]":"277.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"62.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"161.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"327.1","Single Cell Type RNA - Fibroblasts [nTPM]":"161.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"71.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"78.5","Single Cell Type RNA - granulocytes [nTPM]":"149.1","Single Cell Type RNA - Granulosa cells [nTPM]":"173.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"182.4","Single Cell Type RNA - Hepatocytes [nTPM]":"78.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"576.9","Single Cell Type RNA - Horizontal cells [nTPM]":"277.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"63.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"119.0","Single Cell Type RNA - Ionocytes [nTPM]":"201.4","Single Cell Type RNA - Kupffer cells [nTPM]":"137.1","Single Cell Type RNA - Langerhans cells [nTPM]":"162.9","Single Cell Type RNA - Late spermatids [nTPM]":"347.8","Single Cell Type RNA - Leydig cells [nTPM]":"164.7","Single Cell Type RNA - Macrophages [nTPM]":"185.1","Single Cell Type RNA - Melanocytes [nTPM]":"199.3","Single Cell Type RNA - Microglial cells [nTPM]":"34.7","Single Cell Type RNA - monocytes [nTPM]":"369.4","Single Cell Type RNA - Muller glia cells [nTPM]":"199.4","Single Cell Type RNA - NK-cells [nTPM]":"130.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"26.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"46.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"232.1","Single Cell Type RNA - Paneth cells [nTPM]":"153.1","Single Cell Type RNA - Peritubular cells [nTPM]":"214.8","Single Cell Type RNA - Plasma cells [nTPM]":"100.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"138.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"253.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"290.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"58.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"125.9","Single Cell Type RNA - Sertoli cells [nTPM]":"197.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"106.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"278.0","Single Cell Type RNA - Spermatocytes [nTPM]":"83.3","Single Cell Type RNA - Spermatogonia [nTPM]":"101.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"128.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"126.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"513.6","Single Cell Type RNA - T-cells [nTPM]":"102.6","Single Cell Type RNA - Theca cells [nTPM]":"278.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"154.1","Single Cell Type RNA - Urothelial cells [nTPM]":"185.1"},{"Gene":"AP2S1","Gene synonym":["CLAPS2","FBH3","FBHOk","HHC3"],"Ensembl":"ENSG00000042753","Gene description":"Adaptor related protein complex 2 subunit sigma 1","Uniprot":["P53680"],"Chromosome":"19","Position":"46838136-46850846","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Endocytosis","Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"991.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.48e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-2"},"Tissue RNA - adipose tissue [nTPM]":"120.2","Tissue RNA - adrenal gland [nTPM]":"136.5","Tissue RNA - amygdala [nTPM]":"110.7","Tissue RNA - appendix [nTPM]":"80.6","Tissue RNA - basal ganglia [nTPM]":"119.9","Tissue RNA - bone marrow [nTPM]":"126.5","Tissue RNA - breast [nTPM]":"95.9","Tissue RNA - cerebellum [nTPM]":"104.9","Tissue RNA - cerebral cortex [nTPM]":"138.5","Tissue RNA - cervix [nTPM]":"83.0","Tissue RNA - choroid plexus [nTPM]":"99.6","Tissue RNA - colon [nTPM]":"91.5","Tissue RNA - duodenum [nTPM]":"67.3","Tissue RNA - endometrium 1 [nTPM]":"62.1","Tissue RNA - epididymis [nTPM]":"41.0","Tissue RNA - esophagus [nTPM]":"188.9","Tissue RNA - fallopian tube [nTPM]":"58.6","Tissue RNA - gallbladder [nTPM]":"46.1","Tissue RNA - heart muscle [nTPM]":"107.5","Tissue RNA - hippocampal formation [nTPM]":"122.1","Tissue RNA - hypothalamus [nTPM]":"117.7","Tissue RNA - kidney [nTPM]":"106.8","Tissue RNA - liver [nTPM]":"148.9","Tissue RNA - lung [nTPM]":"90.2","Tissue RNA - lymph node [nTPM]":"62.4","Tissue RNA - medulla oblongata [nTPM]":"108.0","Tissue RNA - midbrain [nTPM]":"103.9","Tissue RNA - ovary [nTPM]":"52.3","Tissue RNA - pancreas [nTPM]":"77.2","Tissue RNA - parathyroid gland [nTPM]":"51.9","Tissue RNA - pituitary gland [nTPM]":"72.4","Tissue RNA - placenta [nTPM]":"79.1","Tissue RNA - pons [nTPM]":"111.9","Tissue RNA - prostate [nTPM]":"90.8","Tissue RNA - rectum [nTPM]":"57.4","Tissue RNA - retina [nTPM]":"27.6","Tissue RNA - salivary gland [nTPM]":"99.8","Tissue RNA - seminal vesicle [nTPM]":"48.8","Tissue RNA - skeletal muscle [nTPM]":"101.6","Tissue RNA - skin 1 [nTPM]":"125.8","Tissue RNA - small intestine [nTPM]":"79.8","Tissue RNA - smooth muscle [nTPM]":"60.1","Tissue RNA - spinal cord [nTPM]":"106.0","Tissue RNA - spleen [nTPM]":"124.6","Tissue RNA - stomach 1 [nTPM]":"85.1","Tissue RNA - testis [nTPM]":"69.2","Tissue RNA - thalamus [nTPM]":"111.3","Tissue RNA - thymus [nTPM]":"67.2","Tissue RNA - thyroid gland [nTPM]":"61.5","Tissue RNA - tongue [nTPM]":"63.7","Tissue RNA - tonsil [nTPM]":"67.6","Tissue RNA - urinary bladder [nTPM]":"82.9","Tissue RNA - vagina [nTPM]":"103.4","Tissue RNA - white matter [nTPM]":"112.5","Cell RNA - A-431 [nTPM]":"380.3","Cell RNA - A549 [nTPM]":"363.2","Cell RNA - AF22 [nTPM]":"181.6","Cell RNA - AN3-CA [nTPM]":"198.7","Cell RNA - ASC diff [nTPM]":"227.1","Cell RNA - ASC TERT1 [nTPM]":"248.7","Cell RNA - BEWO [nTPM]":"122.2","Cell RNA - BJ [nTPM]":"311.0","Cell RNA - BJ hTERT+ [nTPM]":"383.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"349.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"411.0","Cell RNA - CACO-2 [nTPM]":"277.1","Cell RNA - CAPAN-2 [nTPM]":"189.3","Cell RNA - Daudi [nTPM]":"121.1","Cell RNA - EFO-21 [nTPM]":"168.6","Cell RNA - fHDF\/TERT166 [nTPM]":"476.2","Cell RNA - GAMG [nTPM]":"153.6","Cell RNA - HaCaT [nTPM]":"178.8","Cell RNA - HAP1 [nTPM]":"144.9","Cell RNA - HBEC3-KT [nTPM]":"450.6","Cell RNA - HBF TERT88 [nTPM]":"263.9","Cell RNA - HDLM-2 [nTPM]":"115.1","Cell RNA - HEK 293 [nTPM]":"418.6","Cell RNA - HEL [nTPM]":"210.4","Cell RNA - HeLa [nTPM]":"220.6","Cell RNA - Hep G2 [nTPM]":"204.0","Cell RNA - HHSteC [nTPM]":"306.7","Cell RNA - HL-60 [nTPM]":"142.1","Cell RNA - HMC-1 [nTPM]":"150.0","Cell RNA - HSkMC [nTPM]":"317.9","Cell RNA - hTCEpi [nTPM]":"259.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"337.9","Cell RNA - hTERT-HME1 [nTPM]":"281.1","Cell RNA - hTERT-RPE1 [nTPM]":"259.0","Cell RNA - HUVEC TERT2 [nTPM]":"471.1","Cell RNA - JURKAT [nTPM]":"199.5","Cell RNA - K-562 [nTPM]":"186.1","Cell RNA - Karpas-707 [nTPM]":"180.4","Cell RNA - LHCN-M2 [nTPM]":"331.1","Cell RNA - MCF7 [nTPM]":"403.2","Cell RNA - MOLT-4 [nTPM]":"181.1","Cell RNA - NB-4 [nTPM]":"1060.2","Cell RNA - NTERA-2 [nTPM]":"295.7","Cell RNA - OE19 [nTPM]":"341.8","Cell RNA - PC-3 [nTPM]":"268.8","Cell RNA - REH [nTPM]":"142.8","Cell RNA - RH-30 [nTPM]":"167.0","Cell RNA - RPMI-8226 [nTPM]":"170.8","Cell RNA - RPTEC TERT1 [nTPM]":"269.2","Cell RNA - RT4 [nTPM]":"299.9","Cell RNA - SCLC-21H [nTPM]":"177.2","Cell RNA - SH-SY5Y [nTPM]":"258.8","Cell RNA - SiHa [nTPM]":"239.1","Cell RNA - SK-BR-3 [nTPM]":"298.4","Cell RNA - SK-MEL-30 [nTPM]":"377.0","Cell RNA - SuSa [nTPM]":"113.9","Cell RNA - T-47d [nTPM]":"248.6","Cell RNA - THP-1 [nTPM]":"336.4","Cell RNA - TIME [nTPM]":"343.2","Cell RNA - U-138 MG [nTPM]":"246.0","Cell RNA - U-2 OS [nTPM]":"293.8","Cell RNA - U-2197 [nTPM]":"135.3","Cell RNA - U-251 MG [nTPM]":"375.7","Cell RNA - U-266\/70 [nTPM]":"130.8","Cell RNA - U-266\/84 [nTPM]":"302.0","Cell RNA - U-698 [nTPM]":"134.8","Cell RNA - U-87 MG [nTPM]":"439.0","Cell RNA - U-937 [nTPM]":"292.3","Cell RNA - WM-115 [nTPM]":"437.6","Blood RNA - basophil [nTPM]":"278.6","Blood RNA - classical monocyte [nTPM]":"640.3","Blood RNA - eosinophil [nTPM]":"406.6","Blood RNA - gdT-cell [nTPM]":"174.3","Blood RNA - intermediate monocyte [nTPM]":"708.8","Blood RNA - MAIT T-cell [nTPM]":"145.2","Blood RNA - memory B-cell [nTPM]":"211.5","Blood RNA - memory CD4 T-cell [nTPM]":"167.3","Blood RNA - memory CD8 T-cell [nTPM]":"174.5","Blood RNA - myeloid DC [nTPM]":"716.8","Blood RNA - naive B-cell [nTPM]":"198.4","Blood RNA - naive CD4 T-cell [nTPM]":"153.1","Blood RNA - naive CD8 T-cell [nTPM]":"156.3","Blood RNA - neutrophil [nTPM]":"204.6","Blood RNA - NK-cell [nTPM]":"188.5","Blood RNA - non-classical monocyte [nTPM]":"544.6","Blood RNA - plasmacytoid DC [nTPM]":"431.5","Blood RNA - T-reg [nTPM]":"233.8","Blood RNA - total PBMC [nTPM]":"673.1","Brain RNA - amygdala [nTPM]":"110.7","Brain RNA - basal ganglia [nTPM]":"119.9","Brain RNA - cerebellum [nTPM]":"104.9","Brain RNA - cerebral cortex [nTPM]":"138.5","Brain RNA - hippocampal formation [nTPM]":"122.1","Brain RNA - hypothalamus [nTPM]":"117.7","Brain RNA - medulla oblongata [nTPM]":"108.0","Brain RNA - midbrain [nTPM]":"103.9","Brain RNA - pons [nTPM]":"111.9","Brain RNA - spinal cord [nTPM]":"106.0","Brain RNA - thalamus [nTPM]":"111.3","Brain RNA - white matter [nTPM]":"112.5","Single Cell Type RNA - Adipocytes [nTPM]":"129.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"57.2","Single Cell Type RNA - Astrocytes [nTPM]":"10.4","Single Cell Type RNA - B-cells [nTPM]":"85.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"171.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"103.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"341.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"73.4","Single Cell Type RNA - Bipolar cells [nTPM]":"39.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"179.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"227.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"79.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"137.2","Single Cell Type RNA - Club cells [nTPM]":"163.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"95.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"415.2","Single Cell Type RNA - dendritic cells [nTPM]":"100.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"397.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"348.3","Single Cell Type RNA - Ductal cells [nTPM]":"215.6","Single Cell Type RNA - Early spermatids [nTPM]":"80.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"67.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"106.7","Single Cell Type RNA - Endothelial cells [nTPM]":"190.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"163.7","Single Cell Type RNA - Erythroid cells [nTPM]":"250.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"247.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"257.4","Single Cell Type RNA - Fibroblasts [nTPM]":"130.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"95.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"82.5","Single Cell Type RNA - granulocytes [nTPM]":"92.7","Single Cell Type RNA - Granulosa cells [nTPM]":"176.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"396.9","Single Cell Type RNA - Hepatocytes [nTPM]":"308.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"991.6","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"259.6","Single Cell Type RNA - Ionocytes [nTPM]":"164.8","Single Cell Type RNA - Kupffer cells [nTPM]":"515.0","Single Cell Type RNA - Langerhans cells [nTPM]":"389.5","Single Cell Type RNA - Late spermatids [nTPM]":"232.8","Single Cell Type RNA - Leydig cells [nTPM]":"92.6","Single Cell Type RNA - Macrophages [nTPM]":"389.5","Single Cell Type RNA - Melanocytes [nTPM]":"200.9","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"661.1","Single Cell Type RNA - Muller glia cells [nTPM]":"109.4","Single Cell Type RNA - NK-cells [nTPM]":"160.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"249.8","Single Cell Type RNA - Paneth cells [nTPM]":"333.9","Single Cell Type RNA - Peritubular cells [nTPM]":"95.5","Single Cell Type RNA - Plasma cells [nTPM]":"94.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"157.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"442.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"432.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"89.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"42.5","Single Cell Type RNA - Sertoli cells [nTPM]":"98.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"59.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"173.9","Single Cell Type RNA - Spermatocytes [nTPM]":"78.9","Single Cell Type RNA - Spermatogonia [nTPM]":"52.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"252.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"253.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"440.5","Single Cell Type RNA - T-cells [nTPM]":"87.9","Single Cell Type RNA - Theca cells [nTPM]":"230.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"282.1","Single Cell Type RNA - Urothelial cells [nTPM]":"164.3"},{"Gene":"AP4B1","Gene synonym":["BETA-4","SPG47"],"Ensembl":"ENSG00000134262","Gene description":"Adaptor related protein complex 4 subunit beta 1","Uniprot":["Q9Y6B7"],"Chromosome":"1","Position":"113894194-113905201","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"31.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"65.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028162","HPA028652"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA028162":"AB_10610976","HPA028652":"AB_10601451"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.60e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.73e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.7","Tissue RNA - adrenal gland [nTPM]":"8.5","Tissue RNA - amygdala [nTPM]":"12.5","Tissue RNA - appendix [nTPM]":"11.1","Tissue RNA - basal ganglia [nTPM]":"13.1","Tissue RNA - bone marrow [nTPM]":"20.5","Tissue RNA - breast [nTPM]":"9.3","Tissue RNA - cerebellum [nTPM]":"14.6","Tissue RNA - cerebral cortex [nTPM]":"14.6","Tissue RNA - cervix [nTPM]":"11.9","Tissue RNA - choroid plexus [nTPM]":"10.9","Tissue RNA - colon [nTPM]":"11.5","Tissue RNA - duodenum [nTPM]":"10.6","Tissue RNA - endometrium 1 [nTPM]":"9.7","Tissue RNA - epididymis [nTPM]":"14.2","Tissue RNA - esophagus [nTPM]":"12.1","Tissue RNA - fallopian tube [nTPM]":"11.0","Tissue RNA - gallbladder [nTPM]":"7.0","Tissue RNA - heart muscle [nTPM]":"11.2","Tissue RNA - hippocampal formation [nTPM]":"13.0","Tissue RNA - hypothalamus [nTPM]":"13.0","Tissue RNA - kidney [nTPM]":"9.7","Tissue RNA - liver [nTPM]":"8.4","Tissue RNA - lung [nTPM]":"9.5","Tissue RNA - lymph node [nTPM]":"14.3","Tissue RNA - medulla oblongata [nTPM]":"11.6","Tissue RNA - midbrain [nTPM]":"11.4","Tissue RNA - ovary [nTPM]":"13.7","Tissue RNA - pancreas [nTPM]":"14.0","Tissue RNA - parathyroid gland [nTPM]":"4.8","Tissue RNA - pituitary gland [nTPM]":"13.7","Tissue RNA - placenta [nTPM]":"5.9","Tissue RNA - pons [nTPM]":"11.8","Tissue RNA - prostate [nTPM]":"9.6","Tissue RNA - rectum [nTPM]":"12.7","Tissue RNA - retina [nTPM]":"20.0","Tissue RNA - salivary gland [nTPM]":"7.6","Tissue RNA - seminal vesicle [nTPM]":"6.2","Tissue RNA - skeletal muscle [nTPM]":"11.7","Tissue RNA - skin 1 [nTPM]":"11.5","Tissue RNA - small intestine [nTPM]":"12.8","Tissue RNA - smooth muscle [nTPM]":"9.1","Tissue RNA - spinal cord [nTPM]":"11.5","Tissue RNA - spleen [nTPM]":"20.1","Tissue RNA - stomach 1 [nTPM]":"10.4","Tissue RNA - testis [nTPM]":"11.1","Tissue RNA - thalamus [nTPM]":"13.3","Tissue RNA - thymus [nTPM]":"16.1","Tissue RNA - thyroid gland [nTPM]":"11.0","Tissue RNA - tongue [nTPM]":"9.1","Tissue RNA - tonsil [nTPM]":"13.9","Tissue RNA - urinary bladder [nTPM]":"9.2","Tissue RNA - vagina [nTPM]":"10.0","Tissue RNA - white matter [nTPM]":"13.3","Cell RNA - A-431 [nTPM]":"11.0","Cell RNA - A549 [nTPM]":"9.8","Cell RNA - AF22 [nTPM]":"10.0","Cell RNA - AN3-CA [nTPM]":"11.8","Cell RNA - ASC diff [nTPM]":"15.7","Cell RNA - ASC TERT1 [nTPM]":"14.1","Cell RNA - BEWO [nTPM]":"6.4","Cell RNA - BJ [nTPM]":"10.1","Cell RNA - BJ hTERT+ [nTPM]":"9.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.0","Cell RNA - CACO-2 [nTPM]":"6.8","Cell RNA - CAPAN-2 [nTPM]":"7.7","Cell RNA - Daudi [nTPM]":"21.5","Cell RNA - EFO-21 [nTPM]":"15.9","Cell RNA - fHDF\/TERT166 [nTPM]":"12.4","Cell RNA - GAMG [nTPM]":"6.5","Cell RNA - HaCaT [nTPM]":"9.7","Cell RNA - HAP1 [nTPM]":"11.3","Cell RNA - HBEC3-KT [nTPM]":"13.4","Cell RNA - HBF TERT88 [nTPM]":"16.5","Cell RNA - HDLM-2 [nTPM]":"16.6","Cell RNA - HEK 293 [nTPM]":"9.8","Cell RNA - HEL [nTPM]":"17.6","Cell RNA - HeLa [nTPM]":"13.6","Cell RNA - Hep G2 [nTPM]":"8.3","Cell RNA - HHSteC [nTPM]":"9.5","Cell RNA - HL-60 [nTPM]":"19.6","Cell RNA - HMC-1 [nTPM]":"17.3","Cell RNA - HSkMC [nTPM]":"16.1","Cell RNA - hTCEpi [nTPM]":"6.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.5","Cell RNA - hTERT-HME1 [nTPM]":"15.3","Cell RNA - hTERT-RPE1 [nTPM]":"7.8","Cell RNA - HUVEC TERT2 [nTPM]":"22.7","Cell RNA - JURKAT [nTPM]":"20.9","Cell RNA - K-562 [nTPM]":"12.3","Cell RNA - Karpas-707 [nTPM]":"18.5","Cell RNA - LHCN-M2 [nTPM]":"17.6","Cell RNA - MCF7 [nTPM]":"65.2","Cell RNA - MOLT-4 [nTPM]":"15.6","Cell RNA - NB-4 [nTPM]":"21.6","Cell RNA - NTERA-2 [nTPM]":"9.4","Cell RNA - OE19 [nTPM]":"7.7","Cell RNA - PC-3 [nTPM]":"19.0","Cell RNA - REH [nTPM]":"15.0","Cell RNA - RH-30 [nTPM]":"19.5","Cell RNA - RPMI-8226 [nTPM]":"13.3","Cell RNA - RPTEC TERT1 [nTPM]":"13.2","Cell RNA - RT4 [nTPM]":"5.5","Cell RNA - SCLC-21H [nTPM]":"10.2","Cell RNA - SH-SY5Y [nTPM]":"8.5","Cell RNA - SiHa [nTPM]":"10.1","Cell RNA - SK-BR-3 [nTPM]":"19.1","Cell RNA - SK-MEL-30 [nTPM]":"7.8","Cell RNA - SuSa [nTPM]":"9.5","Cell RNA - T-47d [nTPM]":"5.7","Cell RNA - THP-1 [nTPM]":"15.4","Cell RNA - TIME [nTPM]":"21.8","Cell RNA - U-138 MG [nTPM]":"15.0","Cell RNA - U-2 OS [nTPM]":"13.9","Cell RNA - U-2197 [nTPM]":"17.4","Cell RNA - U-251 MG [nTPM]":"20.8","Cell RNA - U-266\/70 [nTPM]":"15.2","Cell RNA - U-266\/84 [nTPM]":"15.8","Cell RNA - U-698 [nTPM]":"21.3","Cell RNA - U-87 MG [nTPM]":"24.6","Cell RNA - U-937 [nTPM]":"26.0","Cell RNA - WM-115 [nTPM]":"25.1","Blood RNA - basophil [nTPM]":"15.9","Blood RNA - classical monocyte [nTPM]":"10.5","Blood RNA - eosinophil [nTPM]":"8.6","Blood RNA - gdT-cell [nTPM]":"14.7","Blood RNA - intermediate monocyte [nTPM]":"10.8","Blood RNA - MAIT T-cell [nTPM]":"15.6","Blood RNA - memory B-cell [nTPM]":"9.5","Blood RNA - memory CD4 T-cell [nTPM]":"11.7","Blood RNA - memory CD8 T-cell [nTPM]":"12.6","Blood RNA - myeloid DC [nTPM]":"12.9","Blood RNA - naive B-cell [nTPM]":"11.9","Blood RNA - naive CD4 T-cell [nTPM]":"12.7","Blood RNA - naive CD8 T-cell [nTPM]":"11.1","Blood RNA - neutrophil [nTPM]":"1.2","Blood RNA - NK-cell [nTPM]":"12.2","Blood RNA - non-classical monocyte [nTPM]":"8.5","Blood RNA - plasmacytoid DC [nTPM]":"9.1","Blood RNA - T-reg [nTPM]":"10.4","Blood RNA - total PBMC [nTPM]":"9.5","Brain RNA - amygdala [nTPM]":"12.5","Brain RNA - basal ganglia [nTPM]":"13.1","Brain RNA - cerebellum [nTPM]":"14.6","Brain RNA - cerebral cortex [nTPM]":"14.6","Brain RNA - hippocampal formation [nTPM]":"13.0","Brain RNA - hypothalamus [nTPM]":"13.0","Brain RNA - medulla oblongata [nTPM]":"11.6","Brain RNA - midbrain [nTPM]":"11.4","Brain RNA - pons [nTPM]":"11.8","Brain RNA - spinal cord [nTPM]":"11.5","Brain RNA - thalamus [nTPM]":"13.3","Brain RNA - white matter [nTPM]":"13.3","Single Cell Type RNA - Adipocytes [nTPM]":"7.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.7","Single Cell Type RNA - Astrocytes [nTPM]":"7.5","Single Cell Type RNA - B-cells [nTPM]":"12.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"6.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"11.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.8","Single Cell Type RNA - dendritic cells [nTPM]":"12.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.7","Single Cell Type RNA - Early spermatids [nTPM]":"3.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.7","Single Cell Type RNA - Endothelial cells [nTPM]":"7.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"18.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.5","Single Cell Type RNA - Fibroblasts [nTPM]":"7.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.2","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"4.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"4.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.2","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.3","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"7.3","Single Cell Type RNA - Langerhans cells [nTPM]":"4.9","Single Cell Type RNA - Late spermatids [nTPM]":"2.3","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"6.9","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"6.1","Single Cell Type RNA - Muller glia cells [nTPM]":"4.7","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.9","Single Cell Type RNA - Paneth cells [nTPM]":"6.9","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"7.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.2","Single Cell Type RNA - Spermatocytes [nTPM]":"16.4","Single Cell Type RNA - Spermatogonia [nTPM]":"11.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.6","Single Cell Type RNA - T-cells [nTPM]":"14.8","Single Cell Type RNA - Theca cells [nTPM]":"6.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.0","Single Cell Type RNA - Urothelial cells [nTPM]":"3.3"},{"Gene":"AP4E1","Gene synonym":["AP-4-EPSILON","SPG51"],"Ensembl":"ENSG00000081014","Gene description":"Adaptor related protein complex 4 subunit epsilon 1","Uniprot":["Q9UPM8"],"Chromosome":"15","Position":"50908672-51005895","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"36.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"2.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041749","HPA041891"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041749":"AB_10794490","HPA041891":"AB_10796462"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.7","Tissue RNA - adrenal gland [nTPM]":"3.0","Tissue RNA - amygdala [nTPM]":"2.5","Tissue RNA - appendix [nTPM]":"4.4","Tissue RNA - basal ganglia [nTPM]":"2.9","Tissue RNA - bone marrow [nTPM]":"3.1","Tissue RNA - breast [nTPM]":"3.0","Tissue RNA - cerebellum [nTPM]":"3.3","Tissue RNA - cerebral cortex [nTPM]":"2.7","Tissue RNA - cervix [nTPM]":"3.7","Tissue RNA - choroid plexus [nTPM]":"3.2","Tissue RNA - colon [nTPM]":"3.6","Tissue RNA - duodenum [nTPM]":"3.0","Tissue RNA - endometrium 1 [nTPM]":"4.3","Tissue RNA - epididymis [nTPM]":"2.1","Tissue RNA - esophagus [nTPM]":"4.7","Tissue RNA - fallopian tube [nTPM]":"3.2","Tissue RNA - gallbladder [nTPM]":"2.6","Tissue RNA - heart muscle [nTPM]":"3.9","Tissue RNA - hippocampal formation [nTPM]":"2.4","Tissue RNA - hypothalamus [nTPM]":"2.6","Tissue RNA - kidney [nTPM]":"2.8","Tissue RNA - liver [nTPM]":"2.9","Tissue RNA - lung [nTPM]":"3.1","Tissue RNA - lymph node [nTPM]":"5.5","Tissue RNA - medulla oblongata [nTPM]":"2.9","Tissue RNA - midbrain [nTPM]":"2.8","Tissue RNA - ovary [nTPM]":"2.9","Tissue RNA - pancreas [nTPM]":"2.2","Tissue RNA - parathyroid gland [nTPM]":"5.1","Tissue RNA - pituitary gland [nTPM]":"2.4","Tissue RNA - placenta [nTPM]":"4.7","Tissue RNA - pons [nTPM]":"2.9","Tissue RNA - prostate [nTPM]":"2.7","Tissue RNA - rectum [nTPM]":"3.4","Tissue RNA - retina [nTPM]":"3.8","Tissue RNA - salivary gland [nTPM]":"3.3","Tissue RNA - seminal vesicle [nTPM]":"2.6","Tissue RNA - skeletal muscle [nTPM]":"8.2","Tissue RNA - skin 1 [nTPM]":"5.4","Tissue RNA - small intestine [nTPM]":"3.2","Tissue RNA - smooth muscle [nTPM]":"4.5","Tissue RNA - spinal cord [nTPM]":"2.6","Tissue RNA - spleen [nTPM]":"4.6","Tissue RNA - stomach 1 [nTPM]":"2.9","Tissue RNA - testis [nTPM]":"3.9","Tissue RNA - thalamus [nTPM]":"3.0","Tissue RNA - thymus [nTPM]":"6.5","Tissue RNA - thyroid gland [nTPM]":"3.8","Tissue RNA - tongue [nTPM]":"6.3","Tissue RNA - tonsil [nTPM]":"4.7","Tissue RNA - urinary bladder [nTPM]":"4.0","Tissue RNA - vagina [nTPM]":"4.1","Tissue RNA - white matter [nTPM]":"3.5","Cell RNA - A-431 [nTPM]":"11.5","Cell RNA - A549 [nTPM]":"8.7","Cell RNA - AF22 [nTPM]":"6.0","Cell RNA - AN3-CA [nTPM]":"7.1","Cell RNA - ASC diff [nTPM]":"7.9","Cell RNA - ASC TERT1 [nTPM]":"12.0","Cell RNA - BEWO [nTPM]":"11.7","Cell RNA - BJ [nTPM]":"11.1","Cell RNA - BJ hTERT+ [nTPM]":"8.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.1","Cell RNA - CACO-2 [nTPM]":"10.7","Cell RNA - CAPAN-2 [nTPM]":"1.8","Cell RNA - Daudi [nTPM]":"11.2","Cell RNA - EFO-21 [nTPM]":"4.3","Cell RNA - fHDF\/TERT166 [nTPM]":"12.5","Cell RNA - GAMG [nTPM]":"10.8","Cell RNA - HaCaT [nTPM]":"13.7","Cell RNA - HAP1 [nTPM]":"9.0","Cell RNA - HBEC3-KT [nTPM]":"9.6","Cell RNA - HBF TERT88 [nTPM]":"12.4","Cell RNA - HDLM-2 [nTPM]":"12.3","Cell RNA - HEK 293 [nTPM]":"4.6","Cell RNA - HEL [nTPM]":"9.8","Cell RNA - HeLa [nTPM]":"14.5","Cell RNA - Hep G2 [nTPM]":"4.3","Cell RNA - HHSteC [nTPM]":"11.1","Cell RNA - HL-60 [nTPM]":"12.1","Cell RNA - HMC-1 [nTPM]":"8.2","Cell RNA - HSkMC [nTPM]":"12.2","Cell RNA - hTCEpi [nTPM]":"11.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.4","Cell RNA - hTERT-HME1 [nTPM]":"21.0","Cell RNA - hTERT-RPE1 [nTPM]":"6.6","Cell RNA - HUVEC TERT2 [nTPM]":"7.2","Cell RNA - JURKAT [nTPM]":"8.8","Cell RNA - K-562 [nTPM]":"9.1","Cell RNA - Karpas-707 [nTPM]":"6.3","Cell RNA - LHCN-M2 [nTPM]":"14.7","Cell RNA - MCF7 [nTPM]":"15.4","Cell RNA - MOLT-4 [nTPM]":"7.1","Cell RNA - NB-4 [nTPM]":"6.9","Cell RNA - NTERA-2 [nTPM]":"3.9","Cell RNA - OE19 [nTPM]":"5.2","Cell RNA - PC-3 [nTPM]":"4.4","Cell RNA - REH [nTPM]":"9.7","Cell RNA - RH-30 [nTPM]":"8.5","Cell RNA - RPMI-8226 [nTPM]":"6.9","Cell RNA - RPTEC TERT1 [nTPM]":"7.9","Cell RNA - RT4 [nTPM]":"10.4","Cell RNA - SCLC-21H [nTPM]":"4.1","Cell RNA - SH-SY5Y [nTPM]":"6.7","Cell RNA - SiHa [nTPM]":"11.8","Cell RNA - SK-BR-3 [nTPM]":"8.4","Cell RNA - SK-MEL-30 [nTPM]":"8.7","Cell RNA - SuSa [nTPM]":"10.7","Cell RNA - T-47d [nTPM]":"7.6","Cell RNA - THP-1 [nTPM]":"11.7","Cell RNA - TIME [nTPM]":"10.0","Cell RNA - U-138 MG [nTPM]":"15.7","Cell RNA - U-2 OS [nTPM]":"5.8","Cell RNA - U-2197 [nTPM]":"9.5","Cell RNA - U-251 MG [nTPM]":"15.9","Cell RNA - U-266\/70 [nTPM]":"9.6","Cell RNA - U-266\/84 [nTPM]":"11.7","Cell RNA - U-698 [nTPM]":"14.1","Cell RNA - U-87 MG [nTPM]":"12.3","Cell RNA - U-937 [nTPM]":"26.1","Cell RNA - WM-115 [nTPM]":"7.3","Blood RNA - basophil [nTPM]":"2.7","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"2.5","Brain RNA - basal ganglia [nTPM]":"2.9","Brain RNA - cerebellum [nTPM]":"3.3","Brain RNA - cerebral cortex [nTPM]":"2.7","Brain RNA - hippocampal formation [nTPM]":"2.4","Brain RNA - hypothalamus [nTPM]":"2.6","Brain RNA - medulla oblongata [nTPM]":"2.9","Brain RNA - midbrain [nTPM]":"2.8","Brain RNA - pons [nTPM]":"2.9","Brain RNA - spinal cord [nTPM]":"2.6","Brain RNA - thalamus [nTPM]":"3.0","Brain RNA - white matter [nTPM]":"3.5","Single Cell Type RNA - Adipocytes [nTPM]":"6.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.1","Single Cell Type RNA - Astrocytes [nTPM]":"17.6","Single Cell Type RNA - B-cells [nTPM]":"8.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"9.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"8.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.3","Single Cell Type RNA - dendritic cells [nTPM]":"7.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"4.9","Single Cell Type RNA - Early spermatids [nTPM]":"2.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.0","Single Cell Type RNA - Endothelial cells [nTPM]":"7.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"6.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"26.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.7","Single Cell Type RNA - Fibroblasts [nTPM]":"4.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.2","Single Cell Type RNA - granulocytes [nTPM]":"10.2","Single Cell Type RNA - Granulosa cells [nTPM]":"7.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"8.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.2","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"27.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.3","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"17.0","Single Cell Type RNA - Langerhans cells [nTPM]":"4.1","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"5.9","Single Cell Type RNA - Macrophages [nTPM]":"10.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"25.3","Single Cell Type RNA - monocytes [nTPM]":"6.5","Single Cell Type RNA - Muller glia cells [nTPM]":"3.9","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"36.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.6","Single Cell Type RNA - Paneth cells [nTPM]":"2.4","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"9.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.6","Single Cell Type RNA - Spermatocytes [nTPM]":"10.2","Single Cell Type RNA - Spermatogonia [nTPM]":"7.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.3","Single Cell Type RNA - T-cells [nTPM]":"9.6","Single Cell Type RNA - Theca cells [nTPM]":"4.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.5","Single Cell Type RNA - Urothelial cells [nTPM]":"2.4"},{"Gene":"AP4M1","Gene synonym":["MU-4","MU-ARP2","SPG50"],"Ensembl":"ENSG00000221838","Gene description":"Adaptor related protein complex 4 subunit mu 1","Uniprot":["O00189"],"Chromosome":"7","Position":"100101549-100110345","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"95.9","Spermatocytes":"84.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066774"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA066774":"AB_2685718"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.63e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.29e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Tissue RNA - adipose tissue [nTPM]":"8.4","Tissue RNA - adrenal gland [nTPM]":"7.3","Tissue RNA - amygdala [nTPM]":"9.9","Tissue RNA - appendix [nTPM]":"4.7","Tissue RNA - basal ganglia [nTPM]":"9.9","Tissue RNA - bone marrow [nTPM]":"4.9","Tissue RNA - breast [nTPM]":"9.6","Tissue RNA - cerebellum [nTPM]":"9.6","Tissue RNA - cerebral cortex [nTPM]":"12.1","Tissue RNA - cervix [nTPM]":"11.4","Tissue RNA - choroid plexus [nTPM]":"10.0","Tissue RNA - colon [nTPM]":"15.2","Tissue RNA - duodenum [nTPM]":"12.5","Tissue RNA - endometrium 1 [nTPM]":"15.7","Tissue RNA - epididymis [nTPM]":"6.1","Tissue RNA - esophagus [nTPM]":"10.3","Tissue RNA - fallopian tube [nTPM]":"12.4","Tissue RNA - gallbladder [nTPM]":"8.5","Tissue RNA - heart muscle [nTPM]":"9.8","Tissue RNA - hippocampal formation [nTPM]":"9.9","Tissue RNA - hypothalamus [nTPM]":"10.0","Tissue RNA - kidney [nTPM]":"10.3","Tissue RNA - liver [nTPM]":"4.7","Tissue RNA - lung [nTPM]":"8.8","Tissue RNA - lymph node [nTPM]":"6.3","Tissue RNA - medulla oblongata [nTPM]":"11.2","Tissue RNA - midbrain [nTPM]":"10.5","Tissue RNA - ovary [nTPM]":"9.3","Tissue RNA - pancreas [nTPM]":"12.3","Tissue RNA - parathyroid gland [nTPM]":"7.7","Tissue RNA - pituitary gland [nTPM]":"15.4","Tissue RNA - placenta [nTPM]":"5.6","Tissue RNA - pons [nTPM]":"10.7","Tissue RNA - prostate [nTPM]":"12.3","Tissue RNA - rectum [nTPM]":"6.2","Tissue RNA - retina [nTPM]":"6.4","Tissue RNA - salivary gland [nTPM]":"10.1","Tissue RNA - seminal vesicle [nTPM]":"11.0","Tissue RNA - skeletal muscle [nTPM]":"10.7","Tissue RNA - skin 1 [nTPM]":"11.7","Tissue RNA - small intestine [nTPM]":"9.9","Tissue RNA - smooth muscle [nTPM]":"8.0","Tissue RNA - spinal cord [nTPM]":"10.0","Tissue RNA - spleen [nTPM]":"7.2","Tissue RNA - stomach 1 [nTPM]":"12.8","Tissue RNA - testis [nTPM]":"32.6","Tissue RNA - thalamus [nTPM]":"10.9","Tissue RNA - thymus [nTPM]":"6.1","Tissue RNA - thyroid gland [nTPM]":"10.9","Tissue RNA - tongue [nTPM]":"5.5","Tissue RNA - tonsil [nTPM]":"4.6","Tissue RNA - urinary bladder [nTPM]":"12.4","Tissue RNA - vagina [nTPM]":"10.3","Tissue RNA - white matter [nTPM]":"10.1","Cell RNA - A-431 [nTPM]":"9.3","Cell RNA - A549 [nTPM]":"13.0","Cell RNA - AF22 [nTPM]":"13.9","Cell RNA - AN3-CA [nTPM]":"35.4","Cell RNA - ASC diff [nTPM]":"7.8","Cell RNA - ASC TERT1 [nTPM]":"17.8","Cell RNA - BEWO [nTPM]":"15.8","Cell RNA - BJ [nTPM]":"5.5","Cell RNA - BJ hTERT+ [nTPM]":"9.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.9","Cell RNA - CACO-2 [nTPM]":"10.6","Cell RNA - CAPAN-2 [nTPM]":"23.7","Cell RNA - Daudi [nTPM]":"11.1","Cell RNA - EFO-21 [nTPM]":"25.2","Cell RNA - fHDF\/TERT166 [nTPM]":"13.4","Cell RNA - GAMG [nTPM]":"10.2","Cell RNA - HaCaT [nTPM]":"9.9","Cell RNA - HAP1 [nTPM]":"6.1","Cell RNA - HBEC3-KT [nTPM]":"12.0","Cell RNA - HBF TERT88 [nTPM]":"3.9","Cell RNA - HDLM-2 [nTPM]":"8.9","Cell RNA - HEK 293 [nTPM]":"8.6","Cell RNA - HEL [nTPM]":"6.2","Cell RNA - HeLa [nTPM]":"12.7","Cell RNA - Hep G2 [nTPM]":"9.4","Cell RNA - HHSteC [nTPM]":"16.2","Cell RNA - HL-60 [nTPM]":"7.2","Cell RNA - HMC-1 [nTPM]":"10.9","Cell RNA - HSkMC [nTPM]":"15.1","Cell RNA - hTCEpi [nTPM]":"20.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.7","Cell RNA - hTERT-HME1 [nTPM]":"12.5","Cell RNA - hTERT-RPE1 [nTPM]":"13.7","Cell RNA - HUVEC TERT2 [nTPM]":"23.5","Cell RNA - JURKAT [nTPM]":"14.3","Cell RNA - K-562 [nTPM]":"11.9","Cell RNA - Karpas-707 [nTPM]":"8.4","Cell RNA - LHCN-M2 [nTPM]":"24.6","Cell RNA - MCF7 [nTPM]":"28.7","Cell RNA - MOLT-4 [nTPM]":"25.9","Cell RNA - NB-4 [nTPM]":"14.1","Cell RNA - NTERA-2 [nTPM]":"10.9","Cell RNA - OE19 [nTPM]":"8.4","Cell RNA - PC-3 [nTPM]":"13.3","Cell RNA - REH [nTPM]":"21.8","Cell RNA - RH-30 [nTPM]":"7.0","Cell RNA - RPMI-8226 [nTPM]":"13.9","Cell RNA - RPTEC TERT1 [nTPM]":"18.0","Cell RNA - RT4 [nTPM]":"11.9","Cell RNA - SCLC-21H [nTPM]":"24.2","Cell RNA - SH-SY5Y [nTPM]":"21.1","Cell RNA - SiHa [nTPM]":"14.0","Cell RNA - SK-BR-3 [nTPM]":"40.9","Cell RNA - SK-MEL-30 [nTPM]":"11.9","Cell RNA - SuSa [nTPM]":"7.9","Cell RNA - T-47d [nTPM]":"18.6","Cell RNA - THP-1 [nTPM]":"14.0","Cell RNA - TIME [nTPM]":"26.0","Cell RNA - U-138 MG [nTPM]":"21.2","Cell RNA - U-2 OS [nTPM]":"16.9","Cell RNA - U-2197 [nTPM]":"19.8","Cell RNA - U-251 MG [nTPM]":"9.4","Cell RNA - U-266\/70 [nTPM]":"6.2","Cell RNA - U-266\/84 [nTPM]":"6.8","Cell RNA - U-698 [nTPM]":"16.8","Cell RNA - U-87 MG [nTPM]":"17.7","Cell RNA - U-937 [nTPM]":"8.3","Cell RNA - WM-115 [nTPM]":"18.8","Blood RNA - basophil [nTPM]":"4.3","Blood RNA - classical monocyte [nTPM]":"6.3","Blood RNA - eosinophil [nTPM]":"9.1","Blood RNA - gdT-cell [nTPM]":"4.5","Blood RNA - intermediate monocyte [nTPM]":"7.9","Blood RNA - MAIT T-cell [nTPM]":"4.1","Blood RNA - memory B-cell [nTPM]":"5.3","Blood RNA - memory CD4 T-cell [nTPM]":"4.0","Blood RNA - memory CD8 T-cell [nTPM]":"5.1","Blood RNA - myeloid DC [nTPM]":"8.7","Blood RNA - naive B-cell [nTPM]":"3.4","Blood RNA - naive CD4 T-cell [nTPM]":"1.8","Blood RNA - naive CD8 T-cell [nTPM]":"3.2","Blood RNA - neutrophil [nTPM]":"2.1","Blood RNA - NK-cell [nTPM]":"3.2","Blood RNA - non-classical monocyte [nTPM]":"10.8","Blood RNA - plasmacytoid DC [nTPM]":"5.3","Blood RNA - T-reg [nTPM]":"4.5","Blood RNA - total PBMC [nTPM]":"4.3","Brain RNA - amygdala [nTPM]":"9.9","Brain RNA - basal ganglia [nTPM]":"9.9","Brain RNA - cerebellum [nTPM]":"9.6","Brain RNA - cerebral cortex [nTPM]":"12.1","Brain RNA - hippocampal formation [nTPM]":"9.9","Brain RNA - hypothalamus [nTPM]":"10.0","Brain RNA - medulla oblongata [nTPM]":"11.2","Brain RNA - midbrain [nTPM]":"10.5","Brain RNA - pons [nTPM]":"10.7","Brain RNA - spinal cord [nTPM]":"10.0","Brain RNA - thalamus [nTPM]":"10.9","Brain RNA - white matter [nTPM]":"10.1","Single Cell Type RNA - Adipocytes [nTPM]":"12.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.6","Single Cell Type RNA - Astrocytes [nTPM]":"20.5","Single Cell Type RNA - B-cells [nTPM]":"10.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"17.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"13.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.7","Single Cell Type RNA - dendritic cells [nTPM]":"6.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"24.4","Single Cell Type RNA - Early spermatids [nTPM]":"69.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.6","Single Cell Type RNA - Endothelial cells [nTPM]":"12.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.1","Single Cell Type RNA - Erythroid cells [nTPM]":"8.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.1","Single Cell Type RNA - Fibroblasts [nTPM]":"12.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.2","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"22.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.2","Single Cell Type RNA - Hepatocytes [nTPM]":"3.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.9","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.6","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"7.3","Single Cell Type RNA - Langerhans cells [nTPM]":"7.7","Single Cell Type RNA - Late spermatids [nTPM]":"95.9","Single Cell Type RNA - Leydig cells [nTPM]":"14.6","Single Cell Type RNA - Macrophages [nTPM]":"6.9","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"14.5","Single Cell Type RNA - Muller glia cells [nTPM]":"21.0","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.6","Single Cell Type RNA - Paneth cells [nTPM]":"17.7","Single Cell Type RNA - Peritubular cells [nTPM]":"12.8","Single Cell Type RNA - Plasma cells [nTPM]":"5.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"21.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"67.9","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.4","Single Cell Type RNA - Spermatocytes [nTPM]":"84.7","Single Cell Type RNA - Spermatogonia [nTPM]":"39.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.0","Single Cell Type RNA - T-cells [nTPM]":"8.2","Single Cell Type RNA - Theca cells [nTPM]":"16.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.2","Single Cell Type RNA - Urothelial cells [nTPM]":"11.2"},{"Gene":"AP4S1","Gene synonym":["AP47B","CLA20","SPG52"],"Ensembl":"ENSG00000100478","Gene description":"Adaptor related protein complex 4 subunit sigma 1","Uniprot":["Q9Y587"],"Chromosome":"14","Position":"31025106-31130996","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"36.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039963"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA039963":"AB_10795240"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.44e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.62e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.87e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.8","Tissue RNA - adrenal gland [nTPM]":"6.3","Tissue RNA - amygdala [nTPM]":"9.8","Tissue RNA - appendix [nTPM]":"6.6","Tissue RNA - basal ganglia [nTPM]":"10.6","Tissue RNA - bone marrow [nTPM]":"6.0","Tissue RNA - breast [nTPM]":"5.7","Tissue RNA - cerebellum [nTPM]":"14.1","Tissue RNA - cerebral cortex [nTPM]":"12.8","Tissue RNA - cervix [nTPM]":"6.5","Tissue RNA - choroid plexus [nTPM]":"5.6","Tissue RNA - colon [nTPM]":"8.6","Tissue RNA - duodenum [nTPM]":"3.9","Tissue RNA - endometrium 1 [nTPM]":"7.7","Tissue RNA - epididymis [nTPM]":"7.0","Tissue RNA - esophagus [nTPM]":"4.9","Tissue RNA - fallopian tube [nTPM]":"7.3","Tissue RNA - gallbladder [nTPM]":"5.4","Tissue RNA - heart muscle [nTPM]":"8.7","Tissue RNA - hippocampal formation [nTPM]":"9.5","Tissue RNA - hypothalamus [nTPM]":"10.2","Tissue RNA - kidney [nTPM]":"7.8","Tissue RNA - liver [nTPM]":"6.2","Tissue RNA - lung [nTPM]":"5.4","Tissue RNA - lymph node [nTPM]":"8.1","Tissue RNA - medulla oblongata [nTPM]":"6.3","Tissue RNA - midbrain [nTPM]":"6.5","Tissue RNA - ovary [nTPM]":"10.7","Tissue RNA - pancreas [nTPM]":"7.9","Tissue RNA - parathyroid gland [nTPM]":"6.5","Tissue RNA - pituitary gland [nTPM]":"8.5","Tissue RNA - placenta [nTPM]":"6.7","Tissue RNA - pons [nTPM]":"6.1","Tissue RNA - prostate [nTPM]":"6.2","Tissue RNA - rectum [nTPM]":"4.1","Tissue RNA - retina [nTPM]":"11.9","Tissue RNA - salivary gland [nTPM]":"5.2","Tissue RNA - seminal vesicle [nTPM]":"6.7","Tissue RNA - skeletal muscle [nTPM]":"12.6","Tissue RNA - skin 1 [nTPM]":"4.6","Tissue RNA - small intestine [nTPM]":"4.4","Tissue RNA - smooth muscle [nTPM]":"7.9","Tissue RNA - spinal cord [nTPM]":"5.4","Tissue RNA - spleen [nTPM]":"8.0","Tissue RNA - stomach 1 [nTPM]":"4.3","Tissue RNA - testis [nTPM]":"18.4","Tissue RNA - thalamus [nTPM]":"9.0","Tissue RNA - thymus [nTPM]":"6.6","Tissue RNA - thyroid gland [nTPM]":"8.8","Tissue RNA - tongue [nTPM]":"7.2","Tissue RNA - tonsil [nTPM]":"7.7","Tissue RNA - urinary bladder [nTPM]":"6.2","Tissue RNA - vagina [nTPM]":"4.8","Tissue RNA - white matter [nTPM]":"10.1","Cell RNA - A-431 [nTPM]":"9.0","Cell RNA - A549 [nTPM]":"12.6","Cell RNA - AF22 [nTPM]":"11.0","Cell RNA - AN3-CA [nTPM]":"3.2","Cell RNA - ASC diff [nTPM]":"4.4","Cell RNA - ASC TERT1 [nTPM]":"7.9","Cell RNA - BEWO [nTPM]":"8.5","Cell RNA - BJ [nTPM]":"6.0","Cell RNA - BJ hTERT+ [nTPM]":"10.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.5","Cell RNA - CACO-2 [nTPM]":"12.2","Cell RNA - CAPAN-2 [nTPM]":"14.5","Cell RNA - Daudi [nTPM]":"10.6","Cell RNA - EFO-21 [nTPM]":"5.5","Cell RNA - fHDF\/TERT166 [nTPM]":"7.3","Cell RNA - GAMG [nTPM]":"7.2","Cell RNA - HaCaT [nTPM]":"9.7","Cell RNA - HAP1 [nTPM]":"7.6","Cell RNA - HBEC3-KT [nTPM]":"9.4","Cell RNA - HBF TERT88 [nTPM]":"15.9","Cell RNA - HDLM-2 [nTPM]":"9.1","Cell RNA - HEK 293 [nTPM]":"4.4","Cell RNA - HEL [nTPM]":"16.4","Cell RNA - HeLa [nTPM]":"5.5","Cell RNA - Hep G2 [nTPM]":"19.0","Cell RNA - HHSteC [nTPM]":"9.5","Cell RNA - HL-60 [nTPM]":"14.1","Cell RNA - HMC-1 [nTPM]":"9.2","Cell RNA - HSkMC [nTPM]":"6.3","Cell RNA - hTCEpi [nTPM]":"5.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.6","Cell RNA - hTERT-HME1 [nTPM]":"12.0","Cell RNA - hTERT-RPE1 [nTPM]":"6.4","Cell RNA - HUVEC TERT2 [nTPM]":"11.7","Cell RNA - JURKAT [nTPM]":"8.0","Cell RNA - K-562 [nTPM]":"8.4","Cell RNA - Karpas-707 [nTPM]":"7.0","Cell RNA - LHCN-M2 [nTPM]":"10.3","Cell RNA - MCF7 [nTPM]":"12.5","Cell RNA - MOLT-4 [nTPM]":"9.7","Cell RNA - NB-4 [nTPM]":"7.8","Cell RNA - NTERA-2 [nTPM]":"13.1","Cell RNA - OE19 [nTPM]":"10.5","Cell RNA - PC-3 [nTPM]":"10.9","Cell RNA - REH [nTPM]":"10.3","Cell RNA - RH-30 [nTPM]":"9.8","Cell RNA - RPMI-8226 [nTPM]":"1.4","Cell RNA - RPTEC TERT1 [nTPM]":"10.5","Cell RNA - RT4 [nTPM]":"12.4","Cell RNA - SCLC-21H [nTPM]":"6.1","Cell RNA - SH-SY5Y [nTPM]":"6.1","Cell RNA - SiHa [nTPM]":"10.7","Cell RNA - SK-BR-3 [nTPM]":"5.1","Cell RNA - SK-MEL-30 [nTPM]":"16.3","Cell RNA - SuSa [nTPM]":"7.3","Cell RNA - T-47d [nTPM]":"10.8","Cell RNA - THP-1 [nTPM]":"6.5","Cell RNA - TIME [nTPM]":"8.8","Cell RNA - U-138 MG [nTPM]":"7.3","Cell RNA - U-2 OS [nTPM]":"6.5","Cell RNA - U-2197 [nTPM]":"5.0","Cell RNA - U-251 MG [nTPM]":"5.2","Cell RNA - U-266\/70 [nTPM]":"8.6","Cell RNA - U-266\/84 [nTPM]":"17.0","Cell RNA - U-698 [nTPM]":"15.9","Cell RNA - U-87 MG [nTPM]":"4.2","Cell RNA - U-937 [nTPM]":"4.4","Cell RNA - WM-115 [nTPM]":"5.7","Blood RNA - basophil [nTPM]":"3.4","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"2.4","Blood RNA - gdT-cell [nTPM]":"2.5","Blood RNA - intermediate monocyte [nTPM]":"3.5","Blood RNA - MAIT T-cell [nTPM]":"3.7","Blood RNA - memory B-cell [nTPM]":"3.3","Blood RNA - memory CD4 T-cell [nTPM]":"3.8","Blood RNA - memory CD8 T-cell [nTPM]":"3.0","Blood RNA - myeloid DC [nTPM]":"1.2","Blood RNA - naive B-cell [nTPM]":"3.4","Blood RNA - naive CD4 T-cell [nTPM]":"3.7","Blood RNA - naive CD8 T-cell [nTPM]":"4.5","Blood RNA - neutrophil [nTPM]":"2.6","Blood RNA - NK-cell [nTPM]":"5.8","Blood RNA - non-classical monocyte [nTPM]":"2.8","Blood RNA - plasmacytoid DC [nTPM]":"3.3","Blood RNA - T-reg [nTPM]":"6.6","Blood RNA - total PBMC [nTPM]":"1.7","Brain RNA - amygdala [nTPM]":"9.8","Brain RNA - basal ganglia [nTPM]":"10.6","Brain RNA - cerebellum [nTPM]":"14.1","Brain RNA - cerebral cortex [nTPM]":"12.8","Brain RNA - hippocampal formation [nTPM]":"9.5","Brain RNA - hypothalamus [nTPM]":"10.2","Brain RNA - medulla oblongata [nTPM]":"6.3","Brain RNA - midbrain [nTPM]":"6.5","Brain RNA - pons [nTPM]":"6.1","Brain RNA - spinal cord [nTPM]":"5.4","Brain RNA - thalamus [nTPM]":"9.0","Brain RNA - white matter [nTPM]":"10.1","Single Cell Type RNA - Adipocytes [nTPM]":"7.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.7","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"8.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"12.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"3.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.1","Single Cell Type RNA - dendritic cells [nTPM]":"7.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.6","Single Cell Type RNA - Early spermatids [nTPM]":"21.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.8","Single Cell Type RNA - Endothelial cells [nTPM]":"6.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"29.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.3","Single Cell Type RNA - Fibroblasts [nTPM]":"6.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.8","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"7.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.8","Single Cell Type RNA - Hepatocytes [nTPM]":"4.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.4","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.8","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"5.4","Single Cell Type RNA - Langerhans cells [nTPM]":"4.1","Single Cell Type RNA - Late spermatids [nTPM]":"17.0","Single Cell Type RNA - Leydig cells [nTPM]":"6.8","Single Cell Type RNA - Macrophages [nTPM]":"6.0","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"7.5","Single Cell Type RNA - Muller glia cells [nTPM]":"9.3","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"25.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.8","Single Cell Type RNA - Paneth cells [nTPM]":"6.2","Single Cell Type RNA - Peritubular cells [nTPM]":"8.6","Single Cell Type RNA - Plasma cells [nTPM]":"4.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.1","Single Cell Type RNA - Spermatocytes [nTPM]":"36.0","Single Cell Type RNA - Spermatogonia [nTPM]":"8.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.5","Single Cell Type RNA - T-cells [nTPM]":"7.3","Single Cell Type RNA - Theca cells [nTPM]":"8.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.0","Single Cell Type RNA - Urothelial cells [nTPM]":"5.2"},{"Gene":"APCS","Gene synonym":["MGC88159","PTX2","SAP"],"Ensembl":"ENSG00000132703","Gene description":"Amyloid P component, serum","Uniprot":["P02743"],"Chromosome":"1","Position":"159587826-159588865","Protein class":["Disease related genes","Plasma proteins","Potential drug targets","Predicted secreted proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"76","RNA tissue specific nTPM":{"liver":"3629.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Hepatocytes":"4141.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"25","RNA cancer specific FPKM":{"liver cancer":"826.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RH-30":"1.1"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB007817","HPA053294"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":27700000000,"Blood concentration - Conc. blood MS [pg\/L]":"39000000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB007817":"AB_598185","HPA053294":"AB_2682104"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-3"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"47.7","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"1.3","Tissue RNA - liver [nTPM]":"3629.2","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"9.6","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"1.8","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.9","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"1.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.6","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"6.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"388.9","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"198.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"2.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"45.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"57.8","Single Cell Type RNA - Hepatocytes [nTPM]":"4141.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"88.9","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"3.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"4.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"APOL1","Gene synonym":["APOL"],"Ensembl":"ENSG00000100342","Gene description":"Apolipoprotein L1","Uniprot":["O14791"],"Chromosome":"22","Position":"36253071-36267530","Protein class":["Candidate cardiovascular disease genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Lipid transport","Steroid metabolism","Sterol metabolism","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"220.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"106.1","Glandular and luminal cells":"216.2","Hepatocytes":"115.6","Pancreatic endocrine cells":"105.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"243.9","HDLM-2":"166.1","HHSteC":"120.3","RPTEC TERT1":"91.1","RT4":"146.8"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018885","CAB056156"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":1640000000,"Blood concentration - Conc. blood MS [pg\/L]":"9200000000","Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB056156":"AB_2665576","HPA018885":"AB_1844953"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.35e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.43e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.01e-5"},"Tissue RNA - adipose tissue [nTPM]":"45.3","Tissue RNA - adrenal gland [nTPM]":"15.8","Tissue RNA - amygdala [nTPM]":"8.1","Tissue RNA - appendix [nTPM]":"62.5","Tissue RNA - basal ganglia [nTPM]":"8.2","Tissue RNA - bone marrow [nTPM]":"4.2","Tissue RNA - breast [nTPM]":"28.4","Tissue RNA - cerebellum [nTPM]":"7.8","Tissue RNA - cerebral cortex [nTPM]":"9.8","Tissue RNA - cervix [nTPM]":"53.8","Tissue RNA - choroid plexus [nTPM]":"9.4","Tissue RNA - colon [nTPM]":"32.0","Tissue RNA - duodenum [nTPM]":"32.7","Tissue RNA - endometrium 1 [nTPM]":"38.8","Tissue RNA - epididymis [nTPM]":"17.7","Tissue RNA - esophagus [nTPM]":"25.7","Tissue RNA - fallopian tube [nTPM]":"36.7","Tissue RNA - gallbladder [nTPM]":"69.0","Tissue RNA - heart muscle [nTPM]":"29.5","Tissue RNA - hippocampal formation [nTPM]":"7.4","Tissue RNA - hypothalamus [nTPM]":"8.4","Tissue RNA - kidney [nTPM]":"44.5","Tissue RNA - liver [nTPM]":"220.5","Tissue RNA - lung [nTPM]":"59.5","Tissue RNA - lymph node [nTPM]":"23.1","Tissue RNA - medulla oblongata [nTPM]":"10.0","Tissue RNA - midbrain [nTPM]":"8.5","Tissue RNA - ovary [nTPM]":"24.8","Tissue RNA - pancreas [nTPM]":"9.0","Tissue RNA - parathyroid gland [nTPM]":"4.9","Tissue RNA - pituitary gland [nTPM]":"14.1","Tissue RNA - placenta [nTPM]":"53.0","Tissue RNA - pons [nTPM]":"9.6","Tissue RNA - prostate [nTPM]":"37.5","Tissue RNA - rectum [nTPM]":"27.2","Tissue RNA - retina [nTPM]":"0.9","Tissue RNA - salivary gland [nTPM]":"29.7","Tissue RNA - seminal vesicle [nTPM]":"52.2","Tissue RNA - skeletal muscle [nTPM]":"11.7","Tissue RNA - skin 1 [nTPM]":"7.1","Tissue RNA - small intestine [nTPM]":"28.9","Tissue RNA - smooth muscle [nTPM]":"65.4","Tissue RNA - spinal cord [nTPM]":"9.0","Tissue RNA - spleen [nTPM]":"56.8","Tissue RNA - stomach 1 [nTPM]":"64.9","Tissue RNA - testis [nTPM]":"7.9","Tissue RNA - thalamus [nTPM]":"10.8","Tissue RNA - thymus [nTPM]":"24.9","Tissue RNA - thyroid gland [nTPM]":"18.0","Tissue RNA - tongue [nTPM]":"13.8","Tissue RNA - tonsil [nTPM]":"23.6","Tissue RNA - urinary bladder [nTPM]":"117.7","Tissue RNA - vagina [nTPM]":"29.9","Tissue RNA - white matter [nTPM]":"8.2","Cell RNA - A-431 [nTPM]":"21.6","Cell RNA - A549 [nTPM]":"5.1","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.6","Cell RNA - ASC diff [nTPM]":"46.8","Cell RNA - ASC TERT1 [nTPM]":"44.6","Cell RNA - BEWO [nTPM]":"14.2","Cell RNA - BJ [nTPM]":"2.3","Cell RNA - BJ hTERT+ [nTPM]":"9.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"38.6","Cell RNA - CACO-2 [nTPM]":"0.6","Cell RNA - CAPAN-2 [nTPM]":"34.4","Cell RNA - Daudi [nTPM]":"7.0","Cell RNA - EFO-21 [nTPM]":"243.9","Cell RNA - fHDF\/TERT166 [nTPM]":"24.8","Cell RNA - GAMG [nTPM]":"31.3","Cell RNA - HaCaT [nTPM]":"5.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"19.2","Cell RNA - HBF TERT88 [nTPM]":"3.6","Cell RNA - HDLM-2 [nTPM]":"166.1","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"6.1","Cell RNA - HeLa [nTPM]":"3.2","Cell RNA - Hep G2 [nTPM]":"41.4","Cell RNA - HHSteC [nTPM]":"120.3","Cell RNA - HL-60 [nTPM]":"2.4","Cell RNA - HMC-1 [nTPM]":"20.2","Cell RNA - HSkMC [nTPM]":"8.3","Cell RNA - hTCEpi [nTPM]":"1.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"38.0","Cell RNA - hTERT-HME1 [nTPM]":"0.8","Cell RNA - hTERT-RPE1 [nTPM]":"2.0","Cell RNA - HUVEC TERT2 [nTPM]":"27.3","Cell RNA - JURKAT [nTPM]":"1.3","Cell RNA - K-562 [nTPM]":"23.8","Cell RNA - Karpas-707 [nTPM]":"85.1","Cell RNA - LHCN-M2 [nTPM]":"2.4","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"8.5","Cell RNA - NB-4 [nTPM]":"2.1","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"0.6","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"13.6","Cell RNA - RH-30 [nTPM]":"2.6","Cell RNA - RPMI-8226 [nTPM]":"3.2","Cell RNA - RPTEC TERT1 [nTPM]":"91.1","Cell RNA - RT4 [nTPM]":"146.8","Cell RNA - SCLC-21H [nTPM]":"1.9","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"10.9","Cell RNA - SK-BR-3 [nTPM]":"5.8","Cell RNA - SK-MEL-30 [nTPM]":"2.1","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.8","Cell RNA - THP-1 [nTPM]":"7.8","Cell RNA - TIME [nTPM]":"24.7","Cell RNA - U-138 MG [nTPM]":"29.5","Cell RNA - U-2 OS [nTPM]":"12.4","Cell RNA - U-2197 [nTPM]":"3.2","Cell RNA - U-251 MG [nTPM]":"1.5","Cell RNA - U-266\/70 [nTPM]":"6.5","Cell RNA - U-266\/84 [nTPM]":"4.0","Cell RNA - U-698 [nTPM]":"1.6","Cell RNA - U-87 MG [nTPM]":"16.0","Cell RNA - U-937 [nTPM]":"12.4","Cell RNA - WM-115 [nTPM]":"4.6","Blood RNA - basophil [nTPM]":"15.6","Blood RNA - classical monocyte [nTPM]":"6.1","Blood RNA - eosinophil [nTPM]":"5.5","Blood RNA - gdT-cell [nTPM]":"12.6","Blood RNA - intermediate monocyte [nTPM]":"6.8","Blood RNA - MAIT T-cell [nTPM]":"10.7","Blood RNA - memory B-cell [nTPM]":"2.6","Blood RNA - memory CD4 T-cell [nTPM]":"8.1","Blood RNA - memory CD8 T-cell [nTPM]":"11.2","Blood RNA - myeloid DC [nTPM]":"4.3","Blood RNA - naive B-cell [nTPM]":"1.4","Blood RNA - naive CD4 T-cell [nTPM]":"4.6","Blood RNA - naive CD8 T-cell [nTPM]":"6.3","Blood RNA - neutrophil [nTPM]":"16.1","Blood RNA - NK-cell [nTPM]":"22.4","Blood RNA - non-classical monocyte [nTPM]":"10.3","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"5.4","Blood RNA - total PBMC [nTPM]":"7.2","Brain RNA - amygdala [nTPM]":"8.1","Brain RNA - basal ganglia [nTPM]":"8.2","Brain RNA - cerebellum [nTPM]":"7.8","Brain RNA - cerebral cortex [nTPM]":"9.8","Brain RNA - hippocampal formation [nTPM]":"7.4","Brain RNA - hypothalamus [nTPM]":"8.4","Brain RNA - medulla oblongata [nTPM]":"10.0","Brain RNA - midbrain [nTPM]":"8.5","Brain RNA - pons [nTPM]":"9.6","Brain RNA - spinal cord [nTPM]":"9.0","Brain RNA - thalamus [nTPM]":"10.8","Brain RNA - white matter [nTPM]":"8.2","Single Cell Type RNA - Adipocytes [nTPM]":"37.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"57.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"34.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"7.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"73.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"67.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.0","Single Cell Type RNA - dendritic cells [nTPM]":"12.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"31.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"37.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"106.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"48.8","Single Cell Type RNA - Endothelial cells [nTPM]":"41.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.7","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"20.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.2","Single Cell Type RNA - Fibroblasts [nTPM]":"27.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"45.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"216.2","Single Cell Type RNA - granulocytes [nTPM]":"11.4","Single Cell Type RNA - Granulosa cells [nTPM]":"4.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"49.6","Single Cell Type RNA - Hepatocytes [nTPM]":"115.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.7","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"15.8","Single Cell Type RNA - Langerhans cells [nTPM]":"5.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"27.4","Single Cell Type RNA - Macrophages [nTPM]":"10.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"19.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"36.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"105.1","Single Cell Type RNA - Paneth cells [nTPM]":"19.9","Single Cell Type RNA - Peritubular cells [nTPM]":"24.0","Single Cell Type RNA - Plasma cells [nTPM]":"15.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"31.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"60.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.7","Single Cell Type RNA - T-cells [nTPM]":"12.9","Single Cell Type RNA - Theca cells [nTPM]":"1.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.6","Single Cell Type RNA - Urothelial cells [nTPM]":"62.5"},{"Gene":"APRT","Gene synonym":[],"Ensembl":"ENSG00000198931","Gene description":"Adenine phosphoribosyltransferase","Uniprot":["P07741"],"Chromosome":"16","Position":"88809339-88811937","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Purine salvage"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026681"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1600000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 32: Non-specific - Translation","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA026681":"AB_1844964"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.58e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Tissue RNA - adipose tissue [nTPM]":"118.5","Tissue RNA - adrenal gland [nTPM]":"161.2","Tissue RNA - amygdala [nTPM]":"30.1","Tissue RNA - appendix [nTPM]":"73.6","Tissue RNA - basal ganglia [nTPM]":"30.1","Tissue RNA - bone marrow [nTPM]":"103.1","Tissue RNA - breast [nTPM]":"112.3","Tissue RNA - cerebellum [nTPM]":"32.0","Tissue RNA - cerebral cortex [nTPM]":"39.5","Tissue RNA - cervix [nTPM]":"109.6","Tissue RNA - choroid plexus [nTPM]":"39.3","Tissue RNA - colon [nTPM]":"121.0","Tissue RNA - duodenum [nTPM]":"72.2","Tissue RNA - endometrium 1 [nTPM]":"81.2","Tissue RNA - epididymis [nTPM]":"25.5","Tissue RNA - esophagus [nTPM]":"231.1","Tissue RNA - fallopian tube [nTPM]":"87.6","Tissue RNA - gallbladder [nTPM]":"31.4","Tissue RNA - heart muscle [nTPM]":"70.2","Tissue RNA - hippocampal formation [nTPM]":"29.9","Tissue RNA - hypothalamus [nTPM]":"32.0","Tissue RNA - kidney [nTPM]":"128.7","Tissue RNA - liver [nTPM]":"190.4","Tissue RNA - lung [nTPM]":"85.8","Tissue RNA - lymph node [nTPM]":"83.8","Tissue RNA - medulla oblongata [nTPM]":"32.9","Tissue RNA - midbrain [nTPM]":"31.3","Tissue RNA - ovary [nTPM]":"73.3","Tissue RNA - pancreas [nTPM]":"169.4","Tissue RNA - parathyroid gland [nTPM]":"66.1","Tissue RNA - pituitary gland [nTPM]":"64.9","Tissue RNA - placenta [nTPM]":"37.0","Tissue RNA - pons [nTPM]":"32.1","Tissue RNA - prostate [nTPM]":"113.6","Tissue RNA - rectum [nTPM]":"40.2","Tissue RNA - retina [nTPM]":"5.1","Tissue RNA - salivary gland [nTPM]":"119.8","Tissue RNA - seminal vesicle [nTPM]":"44.6","Tissue RNA - skeletal muscle [nTPM]":"62.7","Tissue RNA - skin 1 [nTPM]":"240.1","Tissue RNA - small intestine [nTPM]":"106.8","Tissue RNA - smooth muscle [nTPM]":"29.8","Tissue RNA - spinal cord [nTPM]":"33.7","Tissue RNA - spleen [nTPM]":"128.6","Tissue RNA - stomach 1 [nTPM]":"131.8","Tissue RNA - testis [nTPM]":"35.2","Tissue RNA - thalamus [nTPM]":"35.1","Tissue RNA - thymus [nTPM]":"77.2","Tissue RNA - thyroid gland [nTPM]":"96.9","Tissue RNA - tongue [nTPM]":"23.8","Tissue RNA - tonsil [nTPM]":"64.5","Tissue RNA - urinary bladder [nTPM]":"95.7","Tissue RNA - vagina [nTPM]":"153.7","Tissue RNA - white matter [nTPM]":"35.7","Cell RNA - A-431 [nTPM]":"157.9","Cell RNA - A549 [nTPM]":"228.3","Cell RNA - AF22 [nTPM]":"44.9","Cell RNA - AN3-CA [nTPM]":"200.4","Cell RNA - ASC diff [nTPM]":"54.2","Cell RNA - ASC TERT1 [nTPM]":"106.0","Cell RNA - BEWO [nTPM]":"232.2","Cell RNA - BJ [nTPM]":"117.1","Cell RNA - BJ hTERT+ [nTPM]":"105.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"136.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"52.6","Cell RNA - CACO-2 [nTPM]":"237.6","Cell RNA - CAPAN-2 [nTPM]":"189.0","Cell RNA - Daudi [nTPM]":"145.5","Cell RNA - EFO-21 [nTPM]":"221.9","Cell RNA - fHDF\/TERT166 [nTPM]":"68.4","Cell RNA - GAMG [nTPM]":"65.0","Cell RNA - HaCaT [nTPM]":"165.3","Cell RNA - HAP1 [nTPM]":"74.8","Cell RNA - HBEC3-KT [nTPM]":"195.4","Cell RNA - HBF TERT88 [nTPM]":"27.5","Cell RNA - HDLM-2 [nTPM]":"102.9","Cell RNA - HEK 293 [nTPM]":"417.7","Cell RNA - HEL [nTPM]":"124.3","Cell RNA - HeLa [nTPM]":"106.5","Cell RNA - Hep G2 [nTPM]":"253.0","Cell RNA - HHSteC [nTPM]":"168.1","Cell RNA - HL-60 [nTPM]":"87.4","Cell RNA - HMC-1 [nTPM]":"97.7","Cell RNA - HSkMC [nTPM]":"113.1","Cell RNA - hTCEpi [nTPM]":"207.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"109.0","Cell RNA - hTERT-HME1 [nTPM]":"139.4","Cell RNA - hTERT-RPE1 [nTPM]":"63.7","Cell RNA - HUVEC TERT2 [nTPM]":"172.6","Cell RNA - JURKAT [nTPM]":"244.6","Cell RNA - K-562 [nTPM]":"266.6","Cell RNA - Karpas-707 [nTPM]":"107.9","Cell RNA - LHCN-M2 [nTPM]":"71.4","Cell RNA - MCF7 [nTPM]":"586.0","Cell RNA - MOLT-4 [nTPM]":"242.1","Cell RNA - NB-4 [nTPM]":"254.7","Cell RNA - NTERA-2 [nTPM]":"169.4","Cell RNA - OE19 [nTPM]":"169.5","Cell RNA - PC-3 [nTPM]":"288.8","Cell RNA - REH [nTPM]":"259.2","Cell RNA - RH-30 [nTPM]":"69.2","Cell RNA - RPMI-8226 [nTPM]":"351.5","Cell RNA - RPTEC TERT1 [nTPM]":"156.3","Cell RNA - RT4 [nTPM]":"107.0","Cell RNA - SCLC-21H [nTPM]":"218.2","Cell RNA - SH-SY5Y [nTPM]":"132.4","Cell RNA - SiHa [nTPM]":"223.5","Cell RNA - SK-BR-3 [nTPM]":"130.7","Cell RNA - SK-MEL-30 [nTPM]":"131.2","Cell RNA - SuSa [nTPM]":"41.9","Cell RNA - T-47d [nTPM]":"427.9","Cell RNA - THP-1 [nTPM]":"171.1","Cell RNA - TIME [nTPM]":"111.4","Cell RNA - U-138 MG [nTPM]":"122.5","Cell RNA - U-2 OS [nTPM]":"104.9","Cell RNA - U-2197 [nTPM]":"99.5","Cell RNA - U-251 MG [nTPM]":"118.0","Cell RNA - U-266\/70 [nTPM]":"205.9","Cell RNA - U-266\/84 [nTPM]":"186.5","Cell RNA - U-698 [nTPM]":"408.8","Cell RNA - U-87 MG [nTPM]":"179.9","Cell RNA - U-937 [nTPM]":"228.4","Cell RNA - WM-115 [nTPM]":"110.5","Blood RNA - basophil [nTPM]":"77.7","Blood RNA - classical monocyte [nTPM]":"544.5","Blood RNA - eosinophil [nTPM]":"202.8","Blood RNA - gdT-cell [nTPM]":"474.5","Blood RNA - intermediate monocyte [nTPM]":"473.5","Blood RNA - MAIT T-cell [nTPM]":"631.7","Blood RNA - memory B-cell [nTPM]":"501.1","Blood RNA - memory CD4 T-cell [nTPM]":"612.0","Blood RNA - memory CD8 T-cell [nTPM]":"510.3","Blood RNA - myeloid DC [nTPM]":"562.4","Blood RNA - naive B-cell [nTPM]":"517.3","Blood RNA - naive CD4 T-cell [nTPM]":"557.8","Blood RNA - naive CD8 T-cell [nTPM]":"475.3","Blood RNA - neutrophil [nTPM]":"31.8","Blood RNA - NK-cell [nTPM]":"501.8","Blood RNA - non-classical monocyte [nTPM]":"322.1","Blood RNA - plasmacytoid DC [nTPM]":"731.6","Blood RNA - T-reg [nTPM]":"551.8","Blood RNA - total PBMC [nTPM]":"998.0","Brain RNA - amygdala [nTPM]":"30.1","Brain RNA - basal ganglia [nTPM]":"30.1","Brain RNA - cerebellum [nTPM]":"32.0","Brain RNA - cerebral cortex [nTPM]":"39.5","Brain RNA - hippocampal formation [nTPM]":"29.9","Brain RNA - hypothalamus [nTPM]":"32.0","Brain RNA - medulla oblongata [nTPM]":"32.9","Brain RNA - midbrain [nTPM]":"31.3","Brain RNA - pons [nTPM]":"32.1","Brain RNA - spinal cord [nTPM]":"33.7","Brain RNA - thalamus [nTPM]":"35.1","Brain RNA - white matter [nTPM]":"35.7","Single Cell Type RNA - Adipocytes [nTPM]":"146.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"115.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"147.4","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"247.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"319.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"320.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"375.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"207.7","Single Cell Type RNA - Bipolar cells [nTPM]":"19.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"346.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"479.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"46.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"230.2","Single Cell Type RNA - Club cells [nTPM]":"206.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"92.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"265.0","Single Cell Type RNA - dendritic cells [nTPM]":"262.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"273.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"406.9","Single Cell Type RNA - Ductal cells [nTPM]":"404.3","Single Cell Type RNA - Early spermatids [nTPM]":"11.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"124.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"180.3","Single Cell Type RNA - Endothelial cells [nTPM]":"163.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"210.8","Single Cell Type RNA - Erythroid cells [nTPM]":"150.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"442.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"401.5","Single Cell Type RNA - Fibroblasts [nTPM]":"170.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"192.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"148.4","Single Cell Type RNA - granulocytes [nTPM]":"131.9","Single Cell Type RNA - Granulosa cells [nTPM]":"154.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"147.8","Single Cell Type RNA - Hepatocytes [nTPM]":"309.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"348.0","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"386.4","Single Cell Type RNA - Ionocytes [nTPM]":"160.7","Single Cell Type RNA - Kupffer cells [nTPM]":"253.9","Single Cell Type RNA - Langerhans cells [nTPM]":"336.1","Single Cell Type RNA - Late spermatids [nTPM]":"35.4","Single Cell Type RNA - Leydig cells [nTPM]":"239.9","Single Cell Type RNA - Macrophages [nTPM]":"214.6","Single Cell Type RNA - Melanocytes [nTPM]":"297.1","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"449.4","Single Cell Type RNA - Muller glia cells [nTPM]":"78.7","Single Cell Type RNA - NK-cells [nTPM]":"355.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"392.3","Single Cell Type RNA - Paneth cells [nTPM]":"228.3","Single Cell Type RNA - Peritubular cells [nTPM]":"135.4","Single Cell Type RNA - Plasma cells [nTPM]":"171.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"404.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"349.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"647.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"125.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"20.4","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"135.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"186.5","Single Cell Type RNA - Spermatocytes [nTPM]":"18.4","Single Cell Type RNA - Spermatogonia [nTPM]":"126.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"358.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"494.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"172.7","Single Cell Type RNA - T-cells [nTPM]":"285.7","Single Cell Type RNA - Theca cells [nTPM]":"339.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"426.7","Single Cell Type RNA - Urothelial cells [nTPM]":"385.2"},{"Gene":"APTX","Gene synonym":["AOA","AOA1","AXA1","EAOH","EOAHA","FLJ20157"],"Ensembl":"ENSG00000137074","Gene description":"Aprataxin","Uniprot":["Q7Z2E3"],"Chromosome":"9","Position":"32886601-33025130","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["DNA-binding","Hydrolase"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064930"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 23: Spermatids - Flagellum & Golgi organization","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA064930":"AB_2685386"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.01e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.7","Tissue RNA - adrenal gland [nTPM]":"14.8","Tissue RNA - amygdala [nTPM]":"14.6","Tissue RNA - appendix [nTPM]":"7.0","Tissue RNA - basal ganglia [nTPM]":"14.8","Tissue RNA - bone marrow [nTPM]":"11.0","Tissue RNA - breast [nTPM]":"10.4","Tissue RNA - cerebellum [nTPM]":"14.8","Tissue RNA - cerebral cortex [nTPM]":"20.2","Tissue RNA - cervix [nTPM]":"9.1","Tissue RNA - choroid plexus [nTPM]":"13.9","Tissue RNA - colon [nTPM]":"10.2","Tissue RNA - duodenum [nTPM]":"8.6","Tissue RNA - endometrium 1 [nTPM]":"8.6","Tissue RNA - epididymis [nTPM]":"7.6","Tissue RNA - esophagus [nTPM]":"14.7","Tissue RNA - fallopian tube [nTPM]":"8.9","Tissue RNA - gallbladder [nTPM]":"4.9","Tissue RNA - heart muscle [nTPM]":"9.9","Tissue RNA - hippocampal formation [nTPM]":"14.8","Tissue RNA - hypothalamus [nTPM]":"15.0","Tissue RNA - kidney [nTPM]":"13.6","Tissue RNA - liver [nTPM]":"15.6","Tissue RNA - lung [nTPM]":"9.3","Tissue RNA - lymph node [nTPM]":"8.1","Tissue RNA - medulla oblongata [nTPM]":"14.7","Tissue RNA - midbrain [nTPM]":"14.6","Tissue RNA - ovary [nTPM]":"8.5","Tissue RNA - pancreas [nTPM]":"9.6","Tissue RNA - parathyroid gland [nTPM]":"12.1","Tissue RNA - pituitary gland [nTPM]":"7.6","Tissue RNA - placenta [nTPM]":"7.8","Tissue RNA - pons [nTPM]":"15.0","Tissue RNA - prostate [nTPM]":"9.6","Tissue RNA - rectum [nTPM]":"11.2","Tissue RNA - retina [nTPM]":"8.0","Tissue RNA - salivary gland [nTPM]":"9.0","Tissue RNA - seminal vesicle [nTPM]":"6.6","Tissue RNA - skeletal muscle [nTPM]":"9.8","Tissue RNA - skin 1 [nTPM]":"15.3","Tissue RNA - small intestine [nTPM]":"8.3","Tissue RNA - smooth muscle [nTPM]":"8.6","Tissue RNA - spinal cord [nTPM]":"14.2","Tissue RNA - spleen [nTPM]":"8.9","Tissue RNA - stomach 1 [nTPM]":"9.7","Tissue RNA - testis [nTPM]":"14.7","Tissue RNA - thalamus [nTPM]":"15.2","Tissue RNA - thymus [nTPM]":"9.3","Tissue RNA - thyroid gland [nTPM]":"7.0","Tissue RNA - tongue [nTPM]":"6.9","Tissue RNA - tonsil [nTPM]":"11.0","Tissue RNA - urinary bladder [nTPM]":"10.4","Tissue RNA - vagina [nTPM]":"9.6","Tissue RNA - white matter [nTPM]":"15.0","Cell RNA - A-431 [nTPM]":"36.2","Cell RNA - A549 [nTPM]":"26.1","Cell RNA - AF22 [nTPM]":"18.4","Cell RNA - AN3-CA [nTPM]":"17.1","Cell RNA - ASC diff [nTPM]":"19.0","Cell RNA - ASC TERT1 [nTPM]":"17.4","Cell RNA - BEWO [nTPM]":"25.6","Cell RNA - BJ [nTPM]":"24.8","Cell RNA - BJ hTERT+ [nTPM]":"26.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"28.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"31.5","Cell RNA - CACO-2 [nTPM]":"35.1","Cell RNA - CAPAN-2 [nTPM]":"12.7","Cell RNA - Daudi [nTPM]":"27.8","Cell RNA - EFO-21 [nTPM]":"14.6","Cell RNA - fHDF\/TERT166 [nTPM]":"21.1","Cell RNA - GAMG [nTPM]":"18.4","Cell RNA - HaCaT [nTPM]":"19.4","Cell RNA - HAP1 [nTPM]":"33.7","Cell RNA - HBEC3-KT [nTPM]":"32.8","Cell RNA - HBF TERT88 [nTPM]":"35.1","Cell RNA - HDLM-2 [nTPM]":"39.2","Cell RNA - HEK 293 [nTPM]":"11.2","Cell RNA - HEL [nTPM]":"17.9","Cell RNA - HeLa [nTPM]":"32.5","Cell RNA - Hep G2 [nTPM]":"37.8","Cell RNA - HHSteC [nTPM]":"24.4","Cell RNA - HL-60 [nTPM]":"29.4","Cell RNA - HMC-1 [nTPM]":"15.1","Cell RNA - HSkMC [nTPM]":"23.8","Cell RNA - hTCEpi [nTPM]":"36.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.5","Cell RNA - hTERT-HME1 [nTPM]":"37.9","Cell RNA - hTERT-RPE1 [nTPM]":"16.9","Cell RNA - HUVEC TERT2 [nTPM]":"26.8","Cell RNA - JURKAT [nTPM]":"20.2","Cell RNA - K-562 [nTPM]":"27.0","Cell RNA - Karpas-707 [nTPM]":"24.2","Cell RNA - LHCN-M2 [nTPM]":"26.0","Cell RNA - MCF7 [nTPM]":"15.6","Cell RNA - MOLT-4 [nTPM]":"24.4","Cell RNA - NB-4 [nTPM]":"43.2","Cell RNA - NTERA-2 [nTPM]":"33.5","Cell RNA - OE19 [nTPM]":"24.4","Cell RNA - PC-3 [nTPM]":"29.0","Cell RNA - REH [nTPM]":"21.2","Cell RNA - RH-30 [nTPM]":"14.4","Cell RNA - RPMI-8226 [nTPM]":"21.5","Cell RNA - RPTEC TERT1 [nTPM]":"25.2","Cell RNA - RT4 [nTPM]":"21.2","Cell RNA - SCLC-21H [nTPM]":"15.6","Cell RNA - SH-SY5Y [nTPM]":"11.1","Cell RNA - SiHa [nTPM]":"21.4","Cell RNA - SK-BR-3 [nTPM]":"18.0","Cell RNA - SK-MEL-30 [nTPM]":"15.5","Cell RNA - SuSa [nTPM]":"17.9","Cell RNA - T-47d [nTPM]":"23.0","Cell RNA - THP-1 [nTPM]":"11.4","Cell RNA - TIME [nTPM]":"17.7","Cell RNA - U-138 MG [nTPM]":"16.2","Cell RNA - U-2 OS [nTPM]":"21.1","Cell RNA - U-2197 [nTPM]":"29.9","Cell RNA - U-251 MG [nTPM]":"25.0","Cell RNA - U-266\/70 [nTPM]":"11.1","Cell RNA - U-266\/84 [nTPM]":"21.2","Cell RNA - U-698 [nTPM]":"27.5","Cell RNA - U-87 MG [nTPM]":"23.4","Cell RNA - U-937 [nTPM]":"23.8","Cell RNA - WM-115 [nTPM]":"13.2","Blood RNA - basophil [nTPM]":"3.3","Blood RNA - classical monocyte [nTPM]":"14.7","Blood RNA - eosinophil [nTPM]":"13.4","Blood RNA - gdT-cell [nTPM]":"12.2","Blood RNA - intermediate monocyte [nTPM]":"15.6","Blood RNA - MAIT T-cell [nTPM]":"15.2","Blood RNA - memory B-cell [nTPM]":"16.3","Blood RNA - memory CD4 T-cell [nTPM]":"12.8","Blood RNA - memory CD8 T-cell [nTPM]":"14.6","Blood RNA - myeloid DC [nTPM]":"17.6","Blood RNA - naive B-cell [nTPM]":"16.1","Blood RNA - naive CD4 T-cell [nTPM]":"16.0","Blood RNA - naive CD8 T-cell [nTPM]":"12.1","Blood RNA - neutrophil [nTPM]":"5.9","Blood RNA - NK-cell [nTPM]":"23.1","Blood RNA - non-classical monocyte [nTPM]":"21.7","Blood RNA - plasmacytoid DC [nTPM]":"15.2","Blood RNA - T-reg [nTPM]":"17.3","Blood RNA - total PBMC [nTPM]":"16.1","Brain RNA - amygdala [nTPM]":"14.6","Brain RNA - basal ganglia [nTPM]":"14.8","Brain RNA - cerebellum [nTPM]":"14.8","Brain RNA - cerebral cortex [nTPM]":"20.2","Brain RNA - hippocampal formation [nTPM]":"14.8","Brain RNA - hypothalamus [nTPM]":"15.0","Brain RNA - medulla oblongata [nTPM]":"14.7","Brain RNA - midbrain [nTPM]":"14.6","Brain RNA - pons [nTPM]":"15.0","Brain RNA - spinal cord [nTPM]":"14.2","Brain RNA - thalamus [nTPM]":"15.2","Brain RNA - white matter [nTPM]":"15.0","Single Cell Type RNA - Adipocytes [nTPM]":"14.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.0","Single Cell Type RNA - Astrocytes [nTPM]":"31.3","Single Cell Type RNA - B-cells [nTPM]":"16.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"32.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.2","Single Cell Type RNA - Bipolar cells [nTPM]":"15.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"23.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.7","Single Cell Type RNA - dendritic cells [nTPM]":"15.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"29.4","Single Cell Type RNA - Ductal cells [nTPM]":"25.3","Single Cell Type RNA - Early spermatids [nTPM]":"55.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.3","Single Cell Type RNA - Endothelial cells [nTPM]":"13.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.8","Single Cell Type RNA - Erythroid cells [nTPM]":"20.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"27.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"28.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"27.7","Single Cell Type RNA - Fibroblasts [nTPM]":"15.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.1","Single Cell Type RNA - granulocytes [nTPM]":"16.5","Single Cell Type RNA - Granulosa cells [nTPM]":"17.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.9","Single Cell Type RNA - Hepatocytes [nTPM]":"21.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.8","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"29.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.3","Single Cell Type RNA - Ionocytes [nTPM]":"34.6","Single Cell Type RNA - Kupffer cells [nTPM]":"14.7","Single Cell Type RNA - Langerhans cells [nTPM]":"9.9","Single Cell Type RNA - Late spermatids [nTPM]":"48.7","Single Cell Type RNA - Leydig cells [nTPM]":"13.4","Single Cell Type RNA - Macrophages [nTPM]":"15.0","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"19.3","Single Cell Type RNA - Muller glia cells [nTPM]":"18.3","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"23.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"43.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"31.9","Single Cell Type RNA - Paneth cells [nTPM]":"6.8","Single Cell Type RNA - Peritubular cells [nTPM]":"10.5","Single Cell Type RNA - Plasma cells [nTPM]":"28.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"24.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"31.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"25.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.2","Single Cell Type RNA - Spermatocytes [nTPM]":"42.2","Single Cell Type RNA - Spermatogonia [nTPM]":"26.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"27.9","Single Cell Type RNA - T-cells [nTPM]":"15.9","Single Cell Type RNA - Theca cells [nTPM]":"20.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.3","Single Cell Type RNA - Urothelial cells [nTPM]":"23.1"},{"Gene":"AQP2","Gene synonym":[],"Ensembl":"ENSG00000167580","Gene description":"Aquaporin 2","Uniprot":["P41181"],"Chromosome":"12","Position":"49950737-49958878","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Diabetes insipidus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"92","RNA tissue specific nTPM":{"kidney":"386.9","seminal vesicle":"212.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"440","RNA single cell type specific nTPM":{"Collecting duct cells":"4143.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"renal cancer":"1.7","stomach cancer":"1.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"3.4","HEL":"1.1","HMC-1":"2.2","OE19":"3.8"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046834"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046834":"AB_2679830"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.38e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"3.2","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.7","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"1.5","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"386.9","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"1.4","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"212.4","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.9","Tissue RNA - testis [nTPM]":"1.4","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.7","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"3.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"1.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"2.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"3.8","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.6","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"4143.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.9","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"9.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"9.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"AQP5","Gene synonym":[],"Ensembl":"ENSG00000161798","Gene description":"Aquaporin 5","Uniprot":["P55064"],"Chromosome":"12","Position":"49961872-49965682","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Palmoplantar keratoderma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"622.6","testis":"222.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Early spermatids":"1542.9","Late spermatids":"4265.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"87.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"22","RNA cell line specific nTPM":{"OE19":"223.2"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065008"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA065008":"AB_2685401"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.00e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.75e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-3"},"Tissue RNA - adipose tissue [nTPM]":"2.9","Tissue RNA - adrenal gland [nTPM]":"0.8","Tissue RNA - amygdala [nTPM]":"2.7","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"3.7","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"17.1","Tissue RNA - cerebellum [nTPM]":"3.3","Tissue RNA - cerebral cortex [nTPM]":"2.7","Tissue RNA - cervix [nTPM]":"12.9","Tissue RNA - choroid plexus [nTPM]":"1.5","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"15.3","Tissue RNA - endometrium 1 [nTPM]":"2.7","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"16.5","Tissue RNA - fallopian tube [nTPM]":"0.7","Tissue RNA - gallbladder [nTPM]":"2.8","Tissue RNA - heart muscle [nTPM]":"4.0","Tissue RNA - hippocampal formation [nTPM]":"2.4","Tissue RNA - hypothalamus [nTPM]":"2.9","Tissue RNA - kidney [nTPM]":"1.9","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"7.6","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"3.3","Tissue RNA - midbrain [nTPM]":"3.9","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"2.0","Tissue RNA - parathyroid gland [nTPM]":"3.0","Tissue RNA - pituitary gland [nTPM]":"1.2","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"3.1","Tissue RNA - prostate [nTPM]":"1.3","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"1.0","Tissue RNA - salivary gland [nTPM]":"622.6","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"112.7","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"2.6","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"52.3","Tissue RNA - testis [nTPM]":"222.0","Tissue RNA - thalamus [nTPM]":"3.8","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"1.6","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"2.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"8.7","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"0.7","Cell RNA - OE19 [nTPM]":"223.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"10.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.3","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.8","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.7","Brain RNA - basal ganglia [nTPM]":"3.7","Brain RNA - cerebellum [nTPM]":"3.3","Brain RNA - cerebral cortex [nTPM]":"2.7","Brain RNA - hippocampal formation [nTPM]":"2.4","Brain RNA - hypothalamus [nTPM]":"2.9","Brain RNA - medulla oblongata [nTPM]":"3.3","Brain RNA - midbrain [nTPM]":"3.9","Brain RNA - pons [nTPM]":"3.1","Brain RNA - spinal cord [nTPM]":"2.6","Brain RNA - thalamus [nTPM]":"3.8","Brain RNA - white matter [nTPM]":"2.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"57.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"53.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"48.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"56.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"1542.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"34.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.6","Single Cell Type RNA - Late spermatids [nTPM]":"4265.6","Single Cell Type RNA - Leydig cells [nTPM]":"28.6","Single Cell Type RNA - Macrophages [nTPM]":"1.7","Single Cell Type RNA - Melanocytes [nTPM]":"295.3","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"53.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"19.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.7","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.8","Single Cell Type RNA - Spermatocytes [nTPM]":"403.9","Single Cell Type RNA - Spermatogonia [nTPM]":"15.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"18.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"ARG1","Gene synonym":[],"Ensembl":"ENSG00000118520","Gene description":"Arginase 1","Uniprot":["P05089"],"Chromosome":"6","Position":"131470832-131584332","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Adaptive immunity","Arginine metabolism","Immunity","Innate immunity","Urea cycle"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"liver":"1203.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"22","RNA single cell type specific nTPM":{"Hepatocytes":"991.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"45","RNA cancer specific FPKM":{"liver cancer":"167.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"neutrophil":"44.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"44.9"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HL-60":"1.4"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebellum":"2.4"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003595","CAB009434","HPA024006","CAB056159","CAB080011"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9500000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009434":"AB_2058955","CAB056159":"AB_2665582","CAB080011":null,"HPA003595":"AB_1078190","HPA024006":"AB_1844987"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.2","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"292.0","Tissue RNA - breast [nTPM]":"4.8","Tissue RNA - cerebellum [nTPM]":"1.0","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"2.1","Tissue RNA - fallopian tube [nTPM]":"1.9","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.8","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"1203.5","Tissue RNA - lung [nTPM]":"6.5","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"1.7","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"0.9","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"92.8","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"20.6","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"1.2","Tissue RNA - thyroid gland [nTPM]":"0.5","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"0.7","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"2.2","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"1.4","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.5","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"1.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"44.9","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"9.3","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"1.0","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"2.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"43.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.2","Single Cell Type RNA - Hepatocytes [nTPM]":"991.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"27.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"2.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"ARIH1","Gene synonym":["ARI","HARI","HHARI","UBCH7BP"],"Ensembl":"ENSG00000166233","Gene description":"Ariadne RBR E3 ubiquitin protein ligase 1","Uniprot":["Q9Y4X5"],"Chromosome":"15","Position":"72474330-72602987","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"47.8","testis":"42.5"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003295"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA003295":"AB_1845017"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.70e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.5","Tissue RNA - adrenal gland [nTPM]":"7.9","Tissue RNA - amygdala [nTPM]":"2.5","Tissue RNA - appendix [nTPM]":"10.1","Tissue RNA - basal ganglia [nTPM]":"3.9","Tissue RNA - bone marrow [nTPM]":"16.5","Tissue RNA - breast [nTPM]":"6.0","Tissue RNA - cerebellum [nTPM]":"7.0","Tissue RNA - cerebral cortex [nTPM]":"5.8","Tissue RNA - cervix [nTPM]":"6.4","Tissue RNA - choroid plexus [nTPM]":"7.1","Tissue RNA - colon [nTPM]":"8.2","Tissue RNA - duodenum [nTPM]":"9.5","Tissue RNA - endometrium 1 [nTPM]":"7.5","Tissue RNA - epididymis [nTPM]":"3.2","Tissue RNA - esophagus [nTPM]":"6.8","Tissue RNA - fallopian tube [nTPM]":"5.4","Tissue RNA - gallbladder [nTPM]":"4.4","Tissue RNA - heart muscle [nTPM]":"11.4","Tissue RNA - hippocampal formation [nTPM]":"4.4","Tissue RNA - hypothalamus [nTPM]":"4.0","Tissue RNA - kidney [nTPM]":"5.2","Tissue RNA - liver [nTPM]":"6.2","Tissue RNA - lung [nTPM]":"7.3","Tissue RNA - lymph node [nTPM]":"4.9","Tissue RNA - medulla oblongata [nTPM]":"3.4","Tissue RNA - midbrain [nTPM]":"2.7","Tissue RNA - ovary [nTPM]":"9.0","Tissue RNA - pancreas [nTPM]":"6.6","Tissue RNA - parathyroid gland [nTPM]":"3.9","Tissue RNA - pituitary gland [nTPM]":"5.9","Tissue RNA - placenta [nTPM]":"6.5","Tissue RNA - pons [nTPM]":"3.6","Tissue RNA - prostate [nTPM]":"5.8","Tissue RNA - rectum [nTPM]":"3.3","Tissue RNA - retina [nTPM]":"10.4","Tissue RNA - salivary gland [nTPM]":"4.3","Tissue RNA - seminal vesicle [nTPM]":"4.8","Tissue RNA - skeletal muscle [nTPM]":"47.8","Tissue RNA - skin 1 [nTPM]":"7.6","Tissue RNA - small intestine [nTPM]":"7.4","Tissue RNA - smooth muscle [nTPM]":"6.3","Tissue RNA - spinal cord [nTPM]":"3.0","Tissue RNA - spleen [nTPM]":"6.0","Tissue RNA - stomach 1 [nTPM]":"6.3","Tissue RNA - testis [nTPM]":"42.5","Tissue RNA - thalamus [nTPM]":"3.8","Tissue RNA - thymus [nTPM]":"3.9","Tissue RNA - thyroid gland [nTPM]":"5.0","Tissue RNA - tongue [nTPM]":"8.5","Tissue RNA - tonsil [nTPM]":"4.1","Tissue RNA - urinary bladder [nTPM]":"7.6","Tissue RNA - vagina [nTPM]":"6.5","Tissue RNA - white matter [nTPM]":"4.3","Cell RNA - A-431 [nTPM]":"17.6","Cell RNA - A549 [nTPM]":"18.0","Cell RNA - AF22 [nTPM]":"17.5","Cell RNA - AN3-CA [nTPM]":"10.2","Cell RNA - ASC diff [nTPM]":"8.9","Cell RNA - ASC TERT1 [nTPM]":"6.2","Cell RNA - BEWO [nTPM]":"20.6","Cell RNA - BJ [nTPM]":"19.3","Cell RNA - BJ hTERT+ [nTPM]":"7.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.9","Cell RNA - CACO-2 [nTPM]":"18.3","Cell RNA - CAPAN-2 [nTPM]":"14.6","Cell RNA - Daudi [nTPM]":"17.2","Cell RNA - EFO-21 [nTPM]":"28.4","Cell RNA - fHDF\/TERT166 [nTPM]":"8.3","Cell RNA - GAMG [nTPM]":"30.3","Cell RNA - HaCaT [nTPM]":"24.8","Cell RNA - HAP1 [nTPM]":"18.1","Cell RNA - HBEC3-KT [nTPM]":"10.1","Cell RNA - HBF TERT88 [nTPM]":"4.8","Cell RNA - HDLM-2 [nTPM]":"30.6","Cell RNA - HEK 293 [nTPM]":"12.4","Cell RNA - HEL [nTPM]":"13.0","Cell RNA - HeLa [nTPM]":"22.5","Cell RNA - Hep G2 [nTPM]":"12.4","Cell RNA - HHSteC [nTPM]":"6.3","Cell RNA - HL-60 [nTPM]":"19.6","Cell RNA - HMC-1 [nTPM]":"14.4","Cell RNA - HSkMC [nTPM]":"7.4","Cell RNA - hTCEpi [nTPM]":"3.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.5","Cell RNA - hTERT-HME1 [nTPM]":"12.2","Cell RNA - hTERT-RPE1 [nTPM]":"8.2","Cell RNA - HUVEC TERT2 [nTPM]":"6.4","Cell RNA - JURKAT [nTPM]":"12.4","Cell RNA - K-562 [nTPM]":"13.8","Cell RNA - Karpas-707 [nTPM]":"19.7","Cell RNA - LHCN-M2 [nTPM]":"8.5","Cell RNA - MCF7 [nTPM]":"11.5","Cell RNA - MOLT-4 [nTPM]":"18.9","Cell RNA - NB-4 [nTPM]":"7.5","Cell RNA - NTERA-2 [nTPM]":"18.9","Cell RNA - OE19 [nTPM]":"6.3","Cell RNA - PC-3 [nTPM]":"6.5","Cell RNA - REH [nTPM]":"21.4","Cell RNA - RH-30 [nTPM]":"21.3","Cell RNA - RPMI-8226 [nTPM]":"9.8","Cell RNA - RPTEC TERT1 [nTPM]":"4.8","Cell RNA - RT4 [nTPM]":"29.0","Cell RNA - SCLC-21H [nTPM]":"16.3","Cell RNA - SH-SY5Y [nTPM]":"18.4","Cell RNA - SiHa [nTPM]":"25.1","Cell RNA - SK-BR-3 [nTPM]":"11.2","Cell RNA - SK-MEL-30 [nTPM]":"31.4","Cell RNA - SuSa [nTPM]":"23.0","Cell RNA - T-47d [nTPM]":"9.0","Cell RNA - THP-1 [nTPM]":"22.0","Cell RNA - TIME [nTPM]":"16.7","Cell RNA - U-138 MG [nTPM]":"14.1","Cell RNA - U-2 OS [nTPM]":"19.6","Cell RNA - U-2197 [nTPM]":"54.8","Cell RNA - U-251 MG [nTPM]":"27.4","Cell RNA - U-266\/70 [nTPM]":"20.7","Cell RNA - U-266\/84 [nTPM]":"45.2","Cell RNA - U-698 [nTPM]":"20.6","Cell RNA - U-87 MG [nTPM]":"9.2","Cell RNA - U-937 [nTPM]":"17.5","Cell RNA - WM-115 [nTPM]":"15.2","Blood RNA - basophil [nTPM]":"1.6","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"2.5","Brain RNA - basal ganglia [nTPM]":"3.9","Brain RNA - cerebellum [nTPM]":"7.0","Brain RNA - cerebral cortex [nTPM]":"5.8","Brain RNA - hippocampal formation [nTPM]":"4.4","Brain RNA - hypothalamus [nTPM]":"4.0","Brain RNA - medulla oblongata [nTPM]":"3.4","Brain RNA - midbrain [nTPM]":"2.7","Brain RNA - pons [nTPM]":"3.6","Brain RNA - spinal cord [nTPM]":"3.0","Brain RNA - thalamus [nTPM]":"3.8","Brain RNA - white matter [nTPM]":"4.3","Single Cell Type RNA - Adipocytes [nTPM]":"79.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"37.7","Single Cell Type RNA - Astrocytes [nTPM]":"88.5","Single Cell Type RNA - B-cells [nTPM]":"64.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"66.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"52.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"76.2","Single Cell Type RNA - Bipolar cells [nTPM]":"63.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"74.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"53.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"46.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"25.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"91.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.4","Single Cell Type RNA - dendritic cells [nTPM]":"83.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"32.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"18.4","Single Cell Type RNA - Early spermatids [nTPM]":"110.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"108.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"84.8","Single Cell Type RNA - Endothelial cells [nTPM]":"50.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"46.5","Single Cell Type RNA - Erythroid cells [nTPM]":"24.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"141.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.8","Single Cell Type RNA - Fibroblasts [nTPM]":"43.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"63.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"148.4","Single Cell Type RNA - granulocytes [nTPM]":"43.2","Single Cell Type RNA - Granulosa cells [nTPM]":"43.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"40.0","Single Cell Type RNA - Hepatocytes [nTPM]":"28.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.0","Single Cell Type RNA - Horizontal cells [nTPM]":"62.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"152.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.2","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"30.5","Single Cell Type RNA - Langerhans cells [nTPM]":"42.1","Single Cell Type RNA - Late spermatids [nTPM]":"55.4","Single Cell Type RNA - Leydig cells [nTPM]":"28.6","Single Cell Type RNA - Macrophages [nTPM]":"67.5","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"104.0","Single Cell Type RNA - monocytes [nTPM]":"24.2","Single Cell Type RNA - Muller glia cells [nTPM]":"25.7","Single Cell Type RNA - NK-cells [nTPM]":"27.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"129.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"135.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"24.7","Single Cell Type RNA - Paneth cells [nTPM]":"19.1","Single Cell Type RNA - Peritubular cells [nTPM]":"27.4","Single Cell Type RNA - Plasma cells [nTPM]":"60.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"55.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"58.8","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"96.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"59.9","Single Cell Type RNA - Spermatocytes [nTPM]":"45.3","Single Cell Type RNA - Spermatogonia [nTPM]":"32.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"68.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"59.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"40.8","Single Cell Type RNA - T-cells [nTPM]":"68.3","Single Cell Type RNA - Theca cells [nTPM]":"36.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"27.0","Single Cell Type RNA - Urothelial cells [nTPM]":"63.7"},{"Gene":"ARSA","Gene synonym":[],"Ensembl":"ENSG00000100299","Gene description":"Arylsulfatase A","Uniprot":["P15289"],"Chromosome":"22","Position":"50622754-50628173","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Ichthyosis","Leukodystrophy","Metachromatic leukodystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"127.5","Plasma cells":"132.0","Proximal enterocytes":"93.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"80.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005554","CAB025183"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5600000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB025183":null,"HPA005554":"AB_1078220"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.96e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-3"},"Tissue RNA - adipose tissue [nTPM]":"28.8","Tissue RNA - adrenal gland [nTPM]":"25.1","Tissue RNA - amygdala [nTPM]":"14.4","Tissue RNA - appendix [nTPM]":"15.6","Tissue RNA - basal ganglia [nTPM]":"18.0","Tissue RNA - bone marrow [nTPM]":"18.4","Tissue RNA - breast [nTPM]":"27.2","Tissue RNA - cerebellum [nTPM]":"16.8","Tissue RNA - cerebral cortex [nTPM]":"21.8","Tissue RNA - cervix [nTPM]":"21.3","Tissue RNA - choroid plexus [nTPM]":"27.5","Tissue RNA - colon [nTPM]":"31.3","Tissue RNA - duodenum [nTPM]":"30.8","Tissue RNA - endometrium 1 [nTPM]":"22.4","Tissue RNA - epididymis [nTPM]":"8.6","Tissue RNA - esophagus [nTPM]":"28.1","Tissue RNA - fallopian tube [nTPM]":"25.1","Tissue RNA - gallbladder [nTPM]":"15.7","Tissue RNA - heart muscle [nTPM]":"33.0","Tissue RNA - hippocampal formation [nTPM]":"14.9","Tissue RNA - hypothalamus [nTPM]":"15.2","Tissue RNA - kidney [nTPM]":"31.4","Tissue RNA - liver [nTPM]":"42.8","Tissue RNA - lung [nTPM]":"29.1","Tissue RNA - lymph node [nTPM]":"19.8","Tissue RNA - medulla oblongata [nTPM]":"20.0","Tissue RNA - midbrain [nTPM]":"15.9","Tissue RNA - ovary [nTPM]":"11.3","Tissue RNA - pancreas [nTPM]":"46.7","Tissue RNA - parathyroid gland [nTPM]":"11.7","Tissue RNA - pituitary gland [nTPM]":"34.7","Tissue RNA - placenta [nTPM]":"10.9","Tissue RNA - pons [nTPM]":"19.1","Tissue RNA - prostate [nTPM]":"28.9","Tissue RNA - rectum [nTPM]":"8.2","Tissue RNA - retina [nTPM]":"4.4","Tissue RNA - salivary gland [nTPM]":"39.6","Tissue RNA - seminal vesicle [nTPM]":"16.2","Tissue RNA - skeletal muscle [nTPM]":"25.3","Tissue RNA - skin 1 [nTPM]":"17.5","Tissue RNA - small intestine [nTPM]":"33.8","Tissue RNA - smooth muscle [nTPM]":"6.5","Tissue RNA - spinal cord [nTPM]":"16.3","Tissue RNA - spleen [nTPM]":"44.5","Tissue RNA - stomach 1 [nTPM]":"30.3","Tissue RNA - testis [nTPM]":"54.0","Tissue RNA - thalamus [nTPM]":"19.4","Tissue RNA - thymus [nTPM]":"9.8","Tissue RNA - thyroid gland [nTPM]":"32.3","Tissue RNA - tongue [nTPM]":"5.1","Tissue RNA - tonsil [nTPM]":"9.5","Tissue RNA - urinary bladder [nTPM]":"23.9","Tissue RNA - vagina [nTPM]":"24.7","Tissue RNA - white matter [nTPM]":"21.0","Cell RNA - A-431 [nTPM]":"8.5","Cell RNA - A549 [nTPM]":"11.0","Cell RNA - AF22 [nTPM]":"5.3","Cell RNA - AN3-CA [nTPM]":"10.9","Cell RNA - ASC diff [nTPM]":"41.8","Cell RNA - ASC TERT1 [nTPM]":"21.8","Cell RNA - BEWO [nTPM]":"13.5","Cell RNA - BJ [nTPM]":"13.0","Cell RNA - BJ hTERT+ [nTPM]":"15.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.3","Cell RNA - CACO-2 [nTPM]":"3.3","Cell RNA - CAPAN-2 [nTPM]":"12.9","Cell RNA - Daudi [nTPM]":"5.3","Cell RNA - EFO-21 [nTPM]":"8.2","Cell RNA - fHDF\/TERT166 [nTPM]":"22.9","Cell RNA - GAMG [nTPM]":"10.8","Cell RNA - HaCaT [nTPM]":"12.8","Cell RNA - HAP1 [nTPM]":"1.2","Cell RNA - HBEC3-KT [nTPM]":"12.3","Cell RNA - HBF TERT88 [nTPM]":"1.0","Cell RNA - HDLM-2 [nTPM]":"2.7","Cell RNA - HEK 293 [nTPM]":"8.0","Cell RNA - HEL [nTPM]":"3.4","Cell RNA - HeLa [nTPM]":"14.3","Cell RNA - Hep G2 [nTPM]":"12.5","Cell RNA - HHSteC [nTPM]":"28.3","Cell RNA - HL-60 [nTPM]":"5.2","Cell RNA - HMC-1 [nTPM]":"32.7","Cell RNA - HSkMC [nTPM]":"26.0","Cell RNA - hTCEpi [nTPM]":"24.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.5","Cell RNA - hTERT-HME1 [nTPM]":"6.3","Cell RNA - hTERT-RPE1 [nTPM]":"19.9","Cell RNA - HUVEC TERT2 [nTPM]":"12.8","Cell RNA - JURKAT [nTPM]":"11.5","Cell RNA - K-562 [nTPM]":"3.5","Cell RNA - Karpas-707 [nTPM]":"80.4","Cell RNA - LHCN-M2 [nTPM]":"12.1","Cell RNA - MCF7 [nTPM]":"9.6","Cell RNA - MOLT-4 [nTPM]":"4.6","Cell RNA - NB-4 [nTPM]":"5.8","Cell RNA - NTERA-2 [nTPM]":"1.7","Cell RNA - OE19 [nTPM]":"9.0","Cell RNA - PC-3 [nTPM]":"11.2","Cell RNA - REH [nTPM]":"4.0","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"26.7","Cell RNA - RPTEC TERT1 [nTPM]":"9.9","Cell RNA - RT4 [nTPM]":"13.5","Cell RNA - SCLC-21H [nTPM]":"2.5","Cell RNA - SH-SY5Y [nTPM]":"8.2","Cell RNA - SiHa [nTPM]":"18.2","Cell RNA - SK-BR-3 [nTPM]":"17.2","Cell RNA - SK-MEL-30 [nTPM]":"10.1","Cell RNA - SuSa [nTPM]":"5.1","Cell RNA - T-47d [nTPM]":"7.7","Cell RNA - THP-1 [nTPM]":"6.6","Cell RNA - TIME [nTPM]":"22.1","Cell RNA - U-138 MG [nTPM]":"3.8","Cell RNA - U-2 OS [nTPM]":"15.1","Cell RNA - U-2197 [nTPM]":"14.9","Cell RNA - U-251 MG [nTPM]":"4.1","Cell RNA - U-266\/70 [nTPM]":"18.4","Cell RNA - U-266\/84 [nTPM]":"1.9","Cell RNA - U-698 [nTPM]":"4.5","Cell RNA - U-87 MG [nTPM]":"11.7","Cell RNA - U-937 [nTPM]":"4.3","Cell RNA - WM-115 [nTPM]":"13.6","Blood RNA - basophil [nTPM]":"10.4","Blood RNA - classical monocyte [nTPM]":"27.7","Blood RNA - eosinophil [nTPM]":"36.1","Blood RNA - gdT-cell [nTPM]":"17.3","Blood RNA - intermediate monocyte [nTPM]":"33.3","Blood RNA - MAIT T-cell [nTPM]":"15.1","Blood RNA - memory B-cell [nTPM]":"10.4","Blood RNA - memory CD4 T-cell [nTPM]":"12.4","Blood RNA - memory CD8 T-cell [nTPM]":"14.2","Blood RNA - myeloid DC [nTPM]":"22.7","Blood RNA - naive B-cell [nTPM]":"12.5","Blood RNA - naive CD4 T-cell [nTPM]":"7.3","Blood RNA - naive CD8 T-cell [nTPM]":"10.0","Blood RNA - neutrophil [nTPM]":"60.4","Blood RNA - NK-cell [nTPM]":"8.9","Blood RNA - non-classical monocyte [nTPM]":"43.2","Blood RNA - plasmacytoid DC [nTPM]":"32.1","Blood RNA - T-reg [nTPM]":"18.2","Blood RNA - total PBMC [nTPM]":"16.3","Brain RNA - amygdala [nTPM]":"14.4","Brain RNA - basal ganglia [nTPM]":"18.0","Brain RNA - cerebellum [nTPM]":"16.8","Brain RNA - cerebral cortex [nTPM]":"21.8","Brain RNA - hippocampal formation [nTPM]":"14.9","Brain RNA - hypothalamus [nTPM]":"15.2","Brain RNA - medulla oblongata [nTPM]":"20.0","Brain RNA - midbrain [nTPM]":"15.9","Brain RNA - pons [nTPM]":"19.1","Brain RNA - spinal cord [nTPM]":"16.3","Brain RNA - thalamus [nTPM]":"19.4","Brain RNA - white matter [nTPM]":"21.0","Single Cell Type RNA - Adipocytes [nTPM]":"22.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.9","Single Cell Type RNA - Astrocytes [nTPM]":"24.5","Single Cell Type RNA - B-cells [nTPM]":"22.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"23.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Bipolar cells [nTPM]":"5.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"15.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.5","Single Cell Type RNA - dendritic cells [nTPM]":"14.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"85.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"29.4","Single Cell Type RNA - Early spermatids [nTPM]":"62.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"24.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.3","Single Cell Type RNA - Endothelial cells [nTPM]":"13.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"36.7","Single Cell Type RNA - Erythroid cells [nTPM]":"9.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.9","Single Cell Type RNA - Fibroblasts [nTPM]":"19.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"41.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.3","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"15.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.2","Single Cell Type RNA - Hepatocytes [nTPM]":"28.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"36.8","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"30.6","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"29.0","Single Cell Type RNA - Langerhans cells [nTPM]":"9.5","Single Cell Type RNA - Late spermatids [nTPM]":"127.5","Single Cell Type RNA - Leydig cells [nTPM]":"10.8","Single Cell Type RNA - Macrophages [nTPM]":"29.2","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"28.7","Single Cell Type RNA - Muller glia cells [nTPM]":"10.3","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"24.2","Single Cell Type RNA - Paneth cells [nTPM]":"75.2","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"132.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"93.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.9","Single Cell Type RNA - Spermatocytes [nTPM]":"48.3","Single Cell Type RNA - Spermatogonia [nTPM]":"4.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"13.3","Single Cell Type RNA - T-cells [nTPM]":"17.2","Single Cell Type RNA - Theca cells [nTPM]":"7.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"25.0","Single Cell Type RNA - Urothelial cells [nTPM]":"16.1"},{"Gene":"ARSB","Gene synonym":[],"Ensembl":"ENSG00000113273","Gene description":"Arylsulfatase B","Uniprot":["P15848"],"Chromosome":"5","Position":"78777209-78986087","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Ichthyosis","Leukodystrophy","Metachromatic leukodystrophy","Mucopolysaccharidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"40.8","Excitatory neurons":"37.4","Inhibitory neurons":"42.5","Microglial cells":"40.3","Oligodendrocyte precursor cells":"71.4","Oligodendrocytes":"56.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"25.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"dendritic cells":"7.8","granulocytes":"25.6","monocytes":"8.3"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037770","HPA037771"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA037770":"AB_10671719","HPA037771":"AB_10671720"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.57e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.42e-4"},"Tissue RNA - adipose tissue [nTPM]":"6.9","Tissue RNA - adrenal gland [nTPM]":"4.5","Tissue RNA - amygdala [nTPM]":"3.9","Tissue RNA - appendix [nTPM]":"8.1","Tissue RNA - basal ganglia [nTPM]":"3.9","Tissue RNA - bone marrow [nTPM]":"8.1","Tissue RNA - breast [nTPM]":"2.6","Tissue RNA - cerebellum [nTPM]":"3.1","Tissue RNA - cerebral cortex [nTPM]":"4.6","Tissue RNA - cervix [nTPM]":"5.3","Tissue RNA - choroid plexus [nTPM]":"4.2","Tissue RNA - colon [nTPM]":"5.5","Tissue RNA - duodenum [nTPM]":"3.1","Tissue RNA - endometrium 1 [nTPM]":"6.4","Tissue RNA - epididymis [nTPM]":"3.5","Tissue RNA - esophagus [nTPM]":"4.8","Tissue RNA - fallopian tube [nTPM]":"2.9","Tissue RNA - gallbladder [nTPM]":"7.3","Tissue RNA - heart muscle [nTPM]":"8.3","Tissue RNA - hippocampal formation [nTPM]":"4.7","Tissue RNA - hypothalamus [nTPM]":"3.6","Tissue RNA - kidney [nTPM]":"21.3","Tissue RNA - liver [nTPM]":"7.6","Tissue RNA - lung [nTPM]":"7.0","Tissue RNA - lymph node [nTPM]":"5.4","Tissue RNA - medulla oblongata [nTPM]":"4.6","Tissue RNA - midbrain [nTPM]":"5.3","Tissue RNA - ovary [nTPM]":"2.2","Tissue RNA - pancreas [nTPM]":"4.6","Tissue RNA - parathyroid gland [nTPM]":"6.6","Tissue RNA - pituitary gland [nTPM]":"2.5","Tissue RNA - placenta [nTPM]":"11.5","Tissue RNA - pons [nTPM]":"4.0","Tissue RNA - prostate [nTPM]":"5.0","Tissue RNA - rectum [nTPM]":"8.2","Tissue RNA - retina [nTPM]":"6.7","Tissue RNA - salivary gland [nTPM]":"3.1","Tissue RNA - seminal vesicle [nTPM]":"6.6","Tissue RNA - skeletal muscle [nTPM]":"3.8","Tissue RNA - skin 1 [nTPM]":"2.1","Tissue RNA - small intestine [nTPM]":"3.6","Tissue RNA - smooth muscle [nTPM]":"14.1","Tissue RNA - spinal cord [nTPM]":"4.3","Tissue RNA - spleen [nTPM]":"5.2","Tissue RNA - stomach 1 [nTPM]":"3.9","Tissue RNA - testis [nTPM]":"2.6","Tissue RNA - thalamus [nTPM]":"5.2","Tissue RNA - thymus [nTPM]":"2.6","Tissue RNA - thyroid gland [nTPM]":"4.2","Tissue RNA - tongue [nTPM]":"4.3","Tissue RNA - tonsil [nTPM]":"4.8","Tissue RNA - urinary bladder [nTPM]":"8.0","Tissue RNA - vagina [nTPM]":"2.3","Tissue RNA - white matter [nTPM]":"5.0","Cell RNA - A-431 [nTPM]":"5.0","Cell RNA - A549 [nTPM]":"11.3","Cell RNA - AF22 [nTPM]":"18.6","Cell RNA - AN3-CA [nTPM]":"6.3","Cell RNA - ASC diff [nTPM]":"41.9","Cell RNA - ASC TERT1 [nTPM]":"16.4","Cell RNA - BEWO [nTPM]":"16.7","Cell RNA - BJ [nTPM]":"29.2","Cell RNA - BJ hTERT+ [nTPM]":"23.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.0","Cell RNA - CACO-2 [nTPM]":"9.9","Cell RNA - CAPAN-2 [nTPM]":"8.4","Cell RNA - Daudi [nTPM]":"6.5","Cell RNA - EFO-21 [nTPM]":"31.5","Cell RNA - fHDF\/TERT166 [nTPM]":"25.5","Cell RNA - GAMG [nTPM]":"29.0","Cell RNA - HaCaT [nTPM]":"3.9","Cell RNA - HAP1 [nTPM]":"7.0","Cell RNA - HBEC3-KT [nTPM]":"7.4","Cell RNA - HBF TERT88 [nTPM]":"18.5","Cell RNA - HDLM-2 [nTPM]":"55.6","Cell RNA - HEK 293 [nTPM]":"6.2","Cell RNA - HEL [nTPM]":"9.2","Cell RNA - HeLa [nTPM]":"11.2","Cell RNA - Hep G2 [nTPM]":"40.1","Cell RNA - HHSteC [nTPM]":"9.7","Cell RNA - HL-60 [nTPM]":"10.5","Cell RNA - HMC-1 [nTPM]":"10.4","Cell RNA - HSkMC [nTPM]":"19.4","Cell RNA - hTCEpi [nTPM]":"2.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.7","Cell RNA - hTERT-HME1 [nTPM]":"6.5","Cell RNA - hTERT-RPE1 [nTPM]":"15.6","Cell RNA - HUVEC TERT2 [nTPM]":"22.4","Cell RNA - JURKAT [nTPM]":"3.9","Cell RNA - K-562 [nTPM]":"2.0","Cell RNA - Karpas-707 [nTPM]":"12.9","Cell RNA - LHCN-M2 [nTPM]":"19.6","Cell RNA - MCF7 [nTPM]":"9.2","Cell RNA - MOLT-4 [nTPM]":"5.8","Cell RNA - NB-4 [nTPM]":"19.3","Cell RNA - NTERA-2 [nTPM]":"5.6","Cell RNA - OE19 [nTPM]":"1.1","Cell RNA - PC-3 [nTPM]":"6.7","Cell RNA - REH [nTPM]":"7.7","Cell RNA - RH-30 [nTPM]":"10.9","Cell RNA - RPMI-8226 [nTPM]":"5.9","Cell RNA - RPTEC TERT1 [nTPM]":"12.0","Cell RNA - RT4 [nTPM]":"6.2","Cell RNA - SCLC-21H [nTPM]":"6.8","Cell RNA - SH-SY5Y [nTPM]":"15.9","Cell RNA - SiHa [nTPM]":"20.3","Cell RNA - SK-BR-3 [nTPM]":"6.2","Cell RNA - SK-MEL-30 [nTPM]":"12.1","Cell RNA - SuSa [nTPM]":"12.7","Cell RNA - T-47d [nTPM]":"6.9","Cell RNA - THP-1 [nTPM]":"26.2","Cell RNA - TIME [nTPM]":"16.2","Cell RNA - U-138 MG [nTPM]":"17.5","Cell RNA - U-2 OS [nTPM]":"10.4","Cell RNA - U-2197 [nTPM]":"7.6","Cell RNA - U-251 MG [nTPM]":"26.4","Cell RNA - U-266\/70 [nTPM]":"14.8","Cell RNA - U-266\/84 [nTPM]":"28.0","Cell RNA - U-698 [nTPM]":"7.2","Cell RNA - U-87 MG [nTPM]":"21.6","Cell RNA - U-937 [nTPM]":"21.4","Cell RNA - WM-115 [nTPM]":"40.3","Blood RNA - basophil [nTPM]":"19.0","Blood RNA - classical monocyte [nTPM]":"8.3","Blood RNA - eosinophil [nTPM]":"25.6","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"6.7","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"2.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"7.8","Blood RNA - naive B-cell [nTPM]":"1.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"4.6","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"5.6","Blood RNA - plasmacytoid DC [nTPM]":"5.7","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"2.7","Brain RNA - amygdala [nTPM]":"3.9","Brain RNA - basal ganglia [nTPM]":"3.9","Brain RNA - cerebellum [nTPM]":"3.1","Brain RNA - cerebral cortex [nTPM]":"4.6","Brain RNA - hippocampal formation [nTPM]":"4.7","Brain RNA - hypothalamus [nTPM]":"3.6","Brain RNA - medulla oblongata [nTPM]":"4.6","Brain RNA - midbrain [nTPM]":"5.3","Brain RNA - pons [nTPM]":"4.0","Brain RNA - spinal cord [nTPM]":"4.3","Brain RNA - thalamus [nTPM]":"5.2","Brain RNA - white matter [nTPM]":"5.0","Single Cell Type RNA - Adipocytes [nTPM]":"3.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.0","Single Cell Type RNA - Astrocytes [nTPM]":"40.8","Single Cell Type RNA - B-cells [nTPM]":"5.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"3.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.2","Single Cell Type RNA - dendritic cells [nTPM]":"5.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.2","Single Cell Type RNA - Endothelial cells [nTPM]":"4.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"16.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"37.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.1","Single Cell Type RNA - Fibroblasts [nTPM]":"6.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"6.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"3.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.7","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"42.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"25.2","Single Cell Type RNA - Langerhans cells [nTPM]":"14.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"4.4","Single Cell Type RNA - Macrophages [nTPM]":"15.9","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"40.3","Single Cell Type RNA - monocytes [nTPM]":"16.1","Single Cell Type RNA - Muller glia cells [nTPM]":"3.6","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"71.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"56.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.0","Single Cell Type RNA - Paneth cells [nTPM]":"3.0","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"8.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.4","Single Cell Type RNA - Spermatocytes [nTPM]":"2.2","Single Cell Type RNA - Spermatogonia [nTPM]":"3.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.6","Single Cell Type RNA - T-cells [nTPM]":"3.4","Single Cell Type RNA - Theca cells [nTPM]":"1.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.2","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"ARSG","Gene synonym":["KIAA1001"],"Ensembl":"ENSG00000141337","Gene description":"Arylsulfatase G","Uniprot":["Q96EG1"],"Chromosome":"17","Position":"68259182-68422731","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Deafness","Disease variant","Retinitis pigmentosa","Usher syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"30.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"54.2","NK-cells":"42.2","Rod photoreceptor cells":"59.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023245","HPA023285"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4400000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 30: Epididymis - Antimicrobial activity","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA023245":"AB_1845056","HPA023285":"AB_1845057"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-7"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.04e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Tissue RNA - adipose tissue [nTPM]":"2.6","Tissue RNA - adrenal gland [nTPM]":"4.6","Tissue RNA - amygdala [nTPM]":"1.5","Tissue RNA - appendix [nTPM]":"2.9","Tissue RNA - basal ganglia [nTPM]":"2.0","Tissue RNA - bone marrow [nTPM]":"3.4","Tissue RNA - breast [nTPM]":"5.5","Tissue RNA - cerebellum [nTPM]":"6.6","Tissue RNA - cerebral cortex [nTPM]":"2.0","Tissue RNA - cervix [nTPM]":"3.5","Tissue RNA - choroid plexus [nTPM]":"8.6","Tissue RNA - colon [nTPM]":"2.2","Tissue RNA - duodenum [nTPM]":"1.1","Tissue RNA - endometrium 1 [nTPM]":"3.8","Tissue RNA - epididymis [nTPM]":"30.2","Tissue RNA - esophagus [nTPM]":"4.4","Tissue RNA - fallopian tube [nTPM]":"6.6","Tissue RNA - gallbladder [nTPM]":"2.1","Tissue RNA - heart muscle [nTPM]":"4.9","Tissue RNA - hippocampal formation [nTPM]":"1.1","Tissue RNA - hypothalamus [nTPM]":"2.9","Tissue RNA - kidney [nTPM]":"3.0","Tissue RNA - liver [nTPM]":"2.5","Tissue RNA - lung [nTPM]":"2.4","Tissue RNA - lymph node [nTPM]":"3.9","Tissue RNA - medulla oblongata [nTPM]":"2.5","Tissue RNA - midbrain [nTPM]":"3.6","Tissue RNA - ovary [nTPM]":"6.2","Tissue RNA - pancreas [nTPM]":"2.3","Tissue RNA - parathyroid gland [nTPM]":"1.2","Tissue RNA - pituitary gland [nTPM]":"5.3","Tissue RNA - placenta [nTPM]":"2.6","Tissue RNA - pons [nTPM]":"3.6","Tissue RNA - prostate [nTPM]":"2.0","Tissue RNA - rectum [nTPM]":"1.1","Tissue RNA - retina [nTPM]":"7.8","Tissue RNA - salivary gland [nTPM]":"3.3","Tissue RNA - seminal vesicle [nTPM]":"5.5","Tissue RNA - skeletal muscle [nTPM]":"3.7","Tissue RNA - skin 1 [nTPM]":"4.5","Tissue RNA - small intestine [nTPM]":"1.9","Tissue RNA - smooth muscle [nTPM]":"2.1","Tissue RNA - spinal cord [nTPM]":"0.7","Tissue RNA - spleen [nTPM]":"4.9","Tissue RNA - stomach 1 [nTPM]":"2.6","Tissue RNA - testis [nTPM]":"2.1","Tissue RNA - thalamus [nTPM]":"2.1","Tissue RNA - thymus [nTPM]":"2.5","Tissue RNA - thyroid gland [nTPM]":"7.5","Tissue RNA - tongue [nTPM]":"3.0","Tissue RNA - tonsil [nTPM]":"3.6","Tissue RNA - urinary bladder [nTPM]":"2.0","Tissue RNA - vagina [nTPM]":"2.0","Tissue RNA - white matter [nTPM]":"1.4","Cell RNA - A-431 [nTPM]":"1.4","Cell RNA - A549 [nTPM]":"1.7","Cell RNA - AF22 [nTPM]":"1.3","Cell RNA - AN3-CA [nTPM]":"2.1","Cell RNA - ASC diff [nTPM]":"7.0","Cell RNA - ASC TERT1 [nTPM]":"4.3","Cell RNA - BEWO [nTPM]":"5.7","Cell RNA - BJ [nTPM]":"1.9","Cell RNA - BJ hTERT+ [nTPM]":"5.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.3","Cell RNA - CACO-2 [nTPM]":"0.7","Cell RNA - CAPAN-2 [nTPM]":"3.2","Cell RNA - Daudi [nTPM]":"3.3","Cell RNA - EFO-21 [nTPM]":"4.8","Cell RNA - fHDF\/TERT166 [nTPM]":"2.5","Cell RNA - GAMG [nTPM]":"1.1","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"2.2","Cell RNA - HBEC3-KT [nTPM]":"0.7","Cell RNA - HBF TERT88 [nTPM]":"1.0","Cell RNA - HDLM-2 [nTPM]":"4.8","Cell RNA - HEK 293 [nTPM]":"2.0","Cell RNA - HEL [nTPM]":"1.8","Cell RNA - HeLa [nTPM]":"1.8","Cell RNA - Hep G2 [nTPM]":"5.4","Cell RNA - HHSteC [nTPM]":"5.7","Cell RNA - HL-60 [nTPM]":"5.1","Cell RNA - HMC-1 [nTPM]":"3.6","Cell RNA - HSkMC [nTPM]":"1.6","Cell RNA - hTCEpi [nTPM]":"1.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.7","Cell RNA - hTERT-HME1 [nTPM]":"2.8","Cell RNA - hTERT-RPE1 [nTPM]":"7.2","Cell RNA - HUVEC TERT2 [nTPM]":"3.1","Cell RNA - JURKAT [nTPM]":"5.0","Cell RNA - K-562 [nTPM]":"1.0","Cell RNA - Karpas-707 [nTPM]":"9.5","Cell RNA - LHCN-M2 [nTPM]":"1.2","Cell RNA - MCF7 [nTPM]":"6.2","Cell RNA - MOLT-4 [nTPM]":"5.9","Cell RNA - NB-4 [nTPM]":"4.1","Cell RNA - NTERA-2 [nTPM]":"2.0","Cell RNA - OE19 [nTPM]":"0.6","Cell RNA - PC-3 [nTPM]":"1.6","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"1.0","Cell RNA - RPMI-8226 [nTPM]":"8.8","Cell RNA - RPTEC TERT1 [nTPM]":"4.1","Cell RNA - RT4 [nTPM]":"0.9","Cell RNA - SCLC-21H [nTPM]":"7.0","Cell RNA - SH-SY5Y [nTPM]":"0.6","Cell RNA - SiHa [nTPM]":"2.3","Cell RNA - SK-BR-3 [nTPM]":"5.5","Cell RNA - SK-MEL-30 [nTPM]":"12.1","Cell RNA - SuSa [nTPM]":"2.7","Cell RNA - T-47d [nTPM]":"13.5","Cell RNA - THP-1 [nTPM]":"6.1","Cell RNA - TIME [nTPM]":"3.3","Cell RNA - U-138 MG [nTPM]":"4.2","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"1.6","Cell RNA - U-251 MG [nTPM]":"0.7","Cell RNA - U-266\/70 [nTPM]":"10.5","Cell RNA - U-266\/84 [nTPM]":"5.8","Cell RNA - U-698 [nTPM]":"5.0","Cell RNA - U-87 MG [nTPM]":"3.3","Cell RNA - U-937 [nTPM]":"6.4","Cell RNA - WM-115 [nTPM]":"1.6","Blood RNA - basophil [nTPM]":"7.1","Blood RNA - classical monocyte [nTPM]":"8.5","Blood RNA - eosinophil [nTPM]":"6.5","Blood RNA - gdT-cell [nTPM]":"6.3","Blood RNA - intermediate monocyte [nTPM]":"6.1","Blood RNA - MAIT T-cell [nTPM]":"4.4","Blood RNA - memory B-cell [nTPM]":"4.0","Blood RNA - memory CD4 T-cell [nTPM]":"4.2","Blood RNA - memory CD8 T-cell [nTPM]":"6.0","Blood RNA - myeloid DC [nTPM]":"7.7","Blood RNA - naive B-cell [nTPM]":"2.2","Blood RNA - naive CD4 T-cell [nTPM]":"4.2","Blood RNA - naive CD8 T-cell [nTPM]":"6.0","Blood RNA - neutrophil [nTPM]":"12.8","Blood RNA - NK-cell [nTPM]":"4.3","Blood RNA - non-classical monocyte [nTPM]":"5.2","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"4.7","Blood RNA - total PBMC [nTPM]":"5.4","Brain RNA - amygdala [nTPM]":"1.5","Brain RNA - basal ganglia [nTPM]":"2.0","Brain RNA - cerebellum [nTPM]":"6.6","Brain RNA - cerebral cortex [nTPM]":"2.0","Brain RNA - hippocampal formation [nTPM]":"1.1","Brain RNA - hypothalamus [nTPM]":"2.9","Brain RNA - medulla oblongata [nTPM]":"2.5","Brain RNA - midbrain [nTPM]":"3.6","Brain RNA - pons [nTPM]":"3.6","Brain RNA - spinal cord [nTPM]":"0.7","Brain RNA - thalamus [nTPM]":"2.1","Brain RNA - white matter [nTPM]":"1.4","Single Cell Type RNA - Adipocytes [nTPM]":"4.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.7","Single Cell Type RNA - Astrocytes [nTPM]":"11.8","Single Cell Type RNA - B-cells [nTPM]":"7.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"23.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"4.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"54.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.1","Single Cell Type RNA - dendritic cells [nTPM]":"11.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"3.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.2","Single Cell Type RNA - Endothelial cells [nTPM]":"8.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"5.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"23.8","Single Cell Type RNA - Fibroblasts [nTPM]":"24.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.7","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"6.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.5","Single Cell Type RNA - Hepatocytes [nTPM]":"3.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.2","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"26.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"6.9","Single Cell Type RNA - Langerhans cells [nTPM]":"10.7","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"13.4","Single Cell Type RNA - Macrophages [nTPM]":"8.4","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"16.0","Single Cell Type RNA - Muller glia cells [nTPM]":"9.4","Single Cell Type RNA - NK-cells [nTPM]":"42.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.3","Single Cell Type RNA - Paneth cells [nTPM]":"10.9","Single Cell Type RNA - Peritubular cells [nTPM]":"23.0","Single Cell Type RNA - Plasma cells [nTPM]":"11.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"59.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.5","Single Cell Type RNA - Spermatocytes [nTPM]":"1.4","Single Cell Type RNA - Spermatogonia [nTPM]":"3.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.8","Single Cell Type RNA - T-cells [nTPM]":"13.6","Single Cell Type RNA - Theca cells [nTPM]":"9.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.3","Single Cell Type RNA - Urothelial cells [nTPM]":"8.8"},{"Gene":"ARV1","Gene synonym":[],"Ensembl":"ENSG00000173409","Gene description":"ARV1 homolog, fatty acid homeostasis modulator","Uniprot":["Q9H2C2"],"Chromosome":"1","Position":"230978981-231000733","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Lipid transport","Steroid metabolism","Sterol metabolism","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"116.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035709"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA035709":"AB_2674744"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.33e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.27e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.12e-3"},"Tissue RNA - adipose tissue [nTPM]":"10.6","Tissue RNA - adrenal gland [nTPM]":"18.4","Tissue RNA - amygdala [nTPM]":"23.4","Tissue RNA - appendix [nTPM]":"10.2","Tissue RNA - basal ganglia [nTPM]":"24.5","Tissue RNA - bone marrow [nTPM]":"13.9","Tissue RNA - breast [nTPM]":"19.0","Tissue RNA - cerebellum [nTPM]":"26.2","Tissue RNA - cerebral cortex [nTPM]":"32.8","Tissue RNA - cervix [nTPM]":"12.2","Tissue RNA - choroid plexus [nTPM]":"25.7","Tissue RNA - colon [nTPM]":"24.6","Tissue RNA - duodenum [nTPM]":"16.4","Tissue RNA - endometrium 1 [nTPM]":"9.7","Tissue RNA - epididymis [nTPM]":"22.9","Tissue RNA - esophagus [nTPM]":"15.7","Tissue RNA - fallopian tube [nTPM]":"14.3","Tissue RNA - gallbladder [nTPM]":"16.4","Tissue RNA - heart muscle [nTPM]":"30.1","Tissue RNA - hippocampal formation [nTPM]":"24.5","Tissue RNA - hypothalamus [nTPM]":"25.6","Tissue RNA - kidney [nTPM]":"25.2","Tissue RNA - liver [nTPM]":"26.2","Tissue RNA - lung [nTPM]":"15.0","Tissue RNA - lymph node [nTPM]":"14.8","Tissue RNA - medulla oblongata [nTPM]":"25.2","Tissue RNA - midbrain [nTPM]":"24.1","Tissue RNA - ovary [nTPM]":"11.2","Tissue RNA - pancreas [nTPM]":"17.5","Tissue RNA - parathyroid gland [nTPM]":"33.3","Tissue RNA - pituitary gland [nTPM]":"20.1","Tissue RNA - placenta [nTPM]":"11.7","Tissue RNA - pons [nTPM]":"25.0","Tissue RNA - prostate [nTPM]":"16.2","Tissue RNA - rectum [nTPM]":"25.9","Tissue RNA - retina [nTPM]":"29.0","Tissue RNA - salivary gland [nTPM]":"22.0","Tissue RNA - seminal vesicle [nTPM]":"15.2","Tissue RNA - skeletal muscle [nTPM]":"21.7","Tissue RNA - skin 1 [nTPM]":"17.8","Tissue RNA - small intestine [nTPM]":"17.3","Tissue RNA - smooth muscle [nTPM]":"13.1","Tissue RNA - spinal cord [nTPM]":"25.7","Tissue RNA - spleen [nTPM]":"13.5","Tissue RNA - stomach 1 [nTPM]":"17.1","Tissue RNA - testis [nTPM]":"31.3","Tissue RNA - thalamus [nTPM]":"25.2","Tissue RNA - thymus [nTPM]":"15.0","Tissue RNA - thyroid gland [nTPM]":"21.9","Tissue RNA - tongue [nTPM]":"24.8","Tissue RNA - tonsil [nTPM]":"15.3","Tissue RNA - urinary bladder [nTPM]":"15.2","Tissue RNA - vagina [nTPM]":"11.2","Tissue RNA - white matter [nTPM]":"27.7","Cell RNA - A-431 [nTPM]":"40.8","Cell RNA - A549 [nTPM]":"43.6","Cell RNA - AF22 [nTPM]":"20.8","Cell RNA - AN3-CA [nTPM]":"25.1","Cell RNA - ASC diff [nTPM]":"29.6","Cell RNA - ASC TERT1 [nTPM]":"26.4","Cell RNA - BEWO [nTPM]":"20.1","Cell RNA - BJ [nTPM]":"19.0","Cell RNA - BJ hTERT+ [nTPM]":"34.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"33.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"38.3","Cell RNA - CACO-2 [nTPM]":"16.3","Cell RNA - CAPAN-2 [nTPM]":"31.4","Cell RNA - Daudi [nTPM]":"11.4","Cell RNA - EFO-21 [nTPM]":"22.7","Cell RNA - fHDF\/TERT166 [nTPM]":"21.3","Cell RNA - GAMG [nTPM]":"20.5","Cell RNA - HaCaT [nTPM]":"32.3","Cell RNA - HAP1 [nTPM]":"40.6","Cell RNA - HBEC3-KT [nTPM]":"25.5","Cell RNA - HBF TERT88 [nTPM]":"39.2","Cell RNA - HDLM-2 [nTPM]":"30.4","Cell RNA - HEK 293 [nTPM]":"55.7","Cell RNA - HEL [nTPM]":"36.8","Cell RNA - HeLa [nTPM]":"28.9","Cell RNA - Hep G2 [nTPM]":"22.1","Cell RNA - HHSteC [nTPM]":"30.5","Cell RNA - HL-60 [nTPM]":"53.6","Cell RNA - HMC-1 [nTPM]":"27.9","Cell RNA - HSkMC [nTPM]":"28.0","Cell RNA - hTCEpi [nTPM]":"25.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.1","Cell RNA - hTERT-HME1 [nTPM]":"20.9","Cell RNA - hTERT-RPE1 [nTPM]":"21.9","Cell RNA - HUVEC TERT2 [nTPM]":"22.5","Cell RNA - JURKAT [nTPM]":"34.7","Cell RNA - K-562 [nTPM]":"53.7","Cell RNA - Karpas-707 [nTPM]":"30.7","Cell RNA - LHCN-M2 [nTPM]":"22.2","Cell RNA - MCF7 [nTPM]":"14.3","Cell RNA - MOLT-4 [nTPM]":"22.3","Cell RNA - NB-4 [nTPM]":"16.4","Cell RNA - NTERA-2 [nTPM]":"27.1","Cell RNA - OE19 [nTPM]":"43.0","Cell RNA - PC-3 [nTPM]":"27.1","Cell RNA - REH [nTPM]":"25.2","Cell RNA - RH-30 [nTPM]":"32.1","Cell RNA - RPMI-8226 [nTPM]":"33.1","Cell RNA - RPTEC TERT1 [nTPM]":"47.1","Cell RNA - RT4 [nTPM]":"33.0","Cell RNA - SCLC-21H [nTPM]":"21.2","Cell RNA - SH-SY5Y [nTPM]":"32.6","Cell RNA - SiHa [nTPM]":"22.6","Cell RNA - SK-BR-3 [nTPM]":"26.6","Cell RNA - SK-MEL-30 [nTPM]":"57.9","Cell RNA - SuSa [nTPM]":"5.3","Cell RNA - T-47d [nTPM]":"46.6","Cell RNA - THP-1 [nTPM]":"46.6","Cell RNA - TIME [nTPM]":"13.9","Cell RNA - U-138 MG [nTPM]":"13.4","Cell RNA - U-2 OS [nTPM]":"8.7","Cell RNA - U-2197 [nTPM]":"23.6","Cell RNA - U-251 MG [nTPM]":"45.9","Cell RNA - U-266\/70 [nTPM]":"47.4","Cell RNA - U-266\/84 [nTPM]":"44.6","Cell RNA - U-698 [nTPM]":"28.9","Cell RNA - U-87 MG [nTPM]":"36.8","Cell RNA - U-937 [nTPM]":"45.9","Cell RNA - WM-115 [nTPM]":"36.7","Blood RNA - basophil [nTPM]":"9.1","Blood RNA - classical monocyte [nTPM]":"8.1","Blood RNA - eosinophil [nTPM]":"8.5","Blood RNA - gdT-cell [nTPM]":"10.0","Blood RNA - intermediate monocyte [nTPM]":"12.2","Blood RNA - MAIT T-cell [nTPM]":"13.9","Blood RNA - memory B-cell [nTPM]":"18.1","Blood RNA - memory CD4 T-cell [nTPM]":"11.2","Blood RNA - memory CD8 T-cell [nTPM]":"12.4","Blood RNA - myeloid DC [nTPM]":"10.1","Blood RNA - naive B-cell [nTPM]":"11.2","Blood RNA - naive CD4 T-cell [nTPM]":"13.7","Blood RNA - naive CD8 T-cell [nTPM]":"13.0","Blood RNA - neutrophil [nTPM]":"2.0","Blood RNA - NK-cell [nTPM]":"12.7","Blood RNA - non-classical monocyte [nTPM]":"21.2","Blood RNA - plasmacytoid DC [nTPM]":"14.9","Blood RNA - T-reg [nTPM]":"15.4","Blood RNA - total PBMC [nTPM]":"9.0","Brain RNA - amygdala [nTPM]":"23.4","Brain RNA - basal ganglia [nTPM]":"24.5","Brain RNA - cerebellum [nTPM]":"26.2","Brain RNA - cerebral cortex [nTPM]":"32.8","Brain RNA - hippocampal formation [nTPM]":"24.5","Brain RNA - hypothalamus [nTPM]":"25.6","Brain RNA - medulla oblongata [nTPM]":"25.2","Brain RNA - midbrain [nTPM]":"24.1","Brain RNA - pons [nTPM]":"25.0","Brain RNA - spinal cord [nTPM]":"25.7","Brain RNA - thalamus [nTPM]":"25.2","Brain RNA - white matter [nTPM]":"27.7","Single Cell Type RNA - Adipocytes [nTPM]":"13.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.7","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"12.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"75.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"18.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"32.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"38.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"37.9","Single Cell Type RNA - dendritic cells [nTPM]":"12.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"60.7","Single Cell Type RNA - Ductal cells [nTPM]":"24.1","Single Cell Type RNA - Early spermatids [nTPM]":"52.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.9","Single Cell Type RNA - Endothelial cells [nTPM]":"12.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.7","Single Cell Type RNA - Erythroid cells [nTPM]":"58.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"20.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"40.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.5","Single Cell Type RNA - Fibroblasts [nTPM]":"14.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.7","Single Cell Type RNA - granulocytes [nTPM]":"17.1","Single Cell Type RNA - Granulosa cells [nTPM]":"14.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.0","Single Cell Type RNA - Hepatocytes [nTPM]":"17.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.9","Single Cell Type RNA - Horizontal cells [nTPM]":"38.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.5","Single Cell Type RNA - Ionocytes [nTPM]":"34.6","Single Cell Type RNA - Kupffer cells [nTPM]":"13.3","Single Cell Type RNA - Langerhans cells [nTPM]":"5.5","Single Cell Type RNA - Late spermatids [nTPM]":"22.9","Single Cell Type RNA - Leydig cells [nTPM]":"9.3","Single Cell Type RNA - Macrophages [nTPM]":"13.5","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"9.8","Single Cell Type RNA - Muller glia cells [nTPM]":"33.6","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.5","Single Cell Type RNA - Paneth cells [nTPM]":"11.5","Single Cell Type RNA - Peritubular cells [nTPM]":"16.6","Single Cell Type RNA - Plasma cells [nTPM]":"14.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"32.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"27.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"20.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.6","Single Cell Type RNA - Spermatocytes [nTPM]":"116.7","Single Cell Type RNA - Spermatogonia [nTPM]":"21.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.6","Single Cell Type RNA - T-cells [nTPM]":"11.4","Single Cell Type RNA - Theca cells [nTPM]":"22.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.4","Single Cell Type RNA - Urothelial cells [nTPM]":"20.9"},{"Gene":"ASAH1","Gene synonym":["AC","ACDase","ASAH","FLJ21558","PHP32"],"Ensembl":"ENSG00000104763","Gene description":"N-acylsphingosine amidohydrolase 1","Uniprot":["Q13510"],"Chromosome":"8","Position":"18055992-18084998","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"573.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"777.0","Hofbauer cells":"921.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"392.8","SK-MEL-30":"590.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005468"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"400000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA005468":"AB_1845062"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.08e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.36e-3"},"Tissue RNA - adipose tissue [nTPM]":"214.3","Tissue RNA - adrenal gland [nTPM]":"71.9","Tissue RNA - amygdala [nTPM]":"50.1","Tissue RNA - appendix [nTPM]":"51.6","Tissue RNA - basal ganglia [nTPM]":"51.5","Tissue RNA - bone marrow [nTPM]":"107.7","Tissue RNA - breast [nTPM]":"95.8","Tissue RNA - cerebellum [nTPM]":"62.1","Tissue RNA - cerebral cortex [nTPM]":"50.8","Tissue RNA - cervix [nTPM]":"98.5","Tissue RNA - choroid plexus [nTPM]":"62.6","Tissue RNA - colon [nTPM]":"84.3","Tissue RNA - duodenum [nTPM]":"54.7","Tissue RNA - endometrium 1 [nTPM]":"55.8","Tissue RNA - epididymis [nTPM]":"131.5","Tissue RNA - esophagus [nTPM]":"73.2","Tissue RNA - fallopian tube [nTPM]":"70.4","Tissue RNA - gallbladder [nTPM]":"99.1","Tissue RNA - heart muscle [nTPM]":"573.9","Tissue RNA - hippocampal formation [nTPM]":"49.9","Tissue RNA - hypothalamus [nTPM]":"66.2","Tissue RNA - kidney [nTPM]":"204.0","Tissue RNA - liver [nTPM]":"60.9","Tissue RNA - lung [nTPM]":"190.3","Tissue RNA - lymph node [nTPM]":"65.9","Tissue RNA - medulla oblongata [nTPM]":"66.0","Tissue RNA - midbrain [nTPM]":"59.4","Tissue RNA - ovary [nTPM]":"50.1","Tissue RNA - pancreas [nTPM]":"49.6","Tissue RNA - parathyroid gland [nTPM]":"117.8","Tissue RNA - pituitary gland [nTPM]":"83.6","Tissue RNA - placenta [nTPM]":"121.5","Tissue RNA - pons [nTPM]":"69.0","Tissue RNA - prostate [nTPM]":"84.3","Tissue RNA - rectum [nTPM]":"87.0","Tissue RNA - retina [nTPM]":"79.5","Tissue RNA - salivary gland [nTPM]":"66.6","Tissue RNA - seminal vesicle [nTPM]":"77.9","Tissue RNA - skeletal muscle [nTPM]":"66.0","Tissue RNA - skin 1 [nTPM]":"52.6","Tissue RNA - small intestine [nTPM]":"56.8","Tissue RNA - smooth muscle [nTPM]":"61.7","Tissue RNA - spinal cord [nTPM]":"66.3","Tissue RNA - spleen [nTPM]":"85.4","Tissue RNA - stomach 1 [nTPM]":"61.2","Tissue RNA - testis [nTPM]":"18.2","Tissue RNA - thalamus [nTPM]":"59.1","Tissue RNA - thymus [nTPM]":"26.0","Tissue RNA - thyroid gland [nTPM]":"325.5","Tissue RNA - tongue [nTPM]":"70.7","Tissue RNA - tonsil [nTPM]":"57.7","Tissue RNA - urinary bladder [nTPM]":"112.8","Tissue RNA - vagina [nTPM]":"54.8","Tissue RNA - white matter [nTPM]":"102.2","Cell RNA - A-431 [nTPM]":"48.1","Cell RNA - A549 [nTPM]":"66.4","Cell RNA - AF22 [nTPM]":"25.9","Cell RNA - AN3-CA [nTPM]":"63.3","Cell RNA - ASC diff [nTPM]":"392.8","Cell RNA - ASC TERT1 [nTPM]":"46.0","Cell RNA - BEWO [nTPM]":"39.2","Cell RNA - BJ [nTPM]":"48.2","Cell RNA - BJ hTERT+ [nTPM]":"67.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"41.0","Cell RNA - CACO-2 [nTPM]":"35.4","Cell RNA - CAPAN-2 [nTPM]":"66.1","Cell RNA - Daudi [nTPM]":"30.2","Cell RNA - EFO-21 [nTPM]":"60.3","Cell RNA - fHDF\/TERT166 [nTPM]":"54.5","Cell RNA - GAMG [nTPM]":"159.1","Cell RNA - HaCaT [nTPM]":"62.6","Cell RNA - HAP1 [nTPM]":"15.0","Cell RNA - HBEC3-KT [nTPM]":"25.3","Cell RNA - HBF TERT88 [nTPM]":"28.4","Cell RNA - HDLM-2 [nTPM]":"22.9","Cell RNA - HEK 293 [nTPM]":"38.9","Cell RNA - HEL [nTPM]":"134.4","Cell RNA - HeLa [nTPM]":"46.7","Cell RNA - Hep G2 [nTPM]":"96.7","Cell RNA - HHSteC [nTPM]":"107.5","Cell RNA - HL-60 [nTPM]":"27.7","Cell RNA - HMC-1 [nTPM]":"140.7","Cell RNA - HSkMC [nTPM]":"100.2","Cell RNA - hTCEpi [nTPM]":"86.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"33.6","Cell RNA - hTERT-HME1 [nTPM]":"22.9","Cell RNA - hTERT-RPE1 [nTPM]":"53.2","Cell RNA - HUVEC TERT2 [nTPM]":"6.2","Cell RNA - JURKAT [nTPM]":"50.6","Cell RNA - K-562 [nTPM]":"24.3","Cell RNA - Karpas-707 [nTPM]":"61.7","Cell RNA - LHCN-M2 [nTPM]":"67.9","Cell RNA - MCF7 [nTPM]":"46.0","Cell RNA - MOLT-4 [nTPM]":"15.5","Cell RNA - NB-4 [nTPM]":"48.3","Cell RNA - NTERA-2 [nTPM]":"30.3","Cell RNA - OE19 [nTPM]":"105.2","Cell RNA - PC-3 [nTPM]":"40.5","Cell RNA - REH [nTPM]":"19.4","Cell RNA - RH-30 [nTPM]":"25.5","Cell RNA - RPMI-8226 [nTPM]":"41.4","Cell RNA - RPTEC TERT1 [nTPM]":"112.0","Cell RNA - RT4 [nTPM]":"273.0","Cell RNA - SCLC-21H [nTPM]":"40.4","Cell RNA - SH-SY5Y [nTPM]":"55.0","Cell RNA - SiHa [nTPM]":"43.8","Cell RNA - SK-BR-3 [nTPM]":"145.2","Cell RNA - SK-MEL-30 [nTPM]":"590.5","Cell RNA - SuSa [nTPM]":"35.6","Cell RNA - T-47d [nTPM]":"47.9","Cell RNA - THP-1 [nTPM]":"31.3","Cell RNA - TIME [nTPM]":"43.6","Cell RNA - U-138 MG [nTPM]":"30.3","Cell RNA - U-2 OS [nTPM]":"43.1","Cell RNA - U-2197 [nTPM]":"55.8","Cell RNA - U-251 MG [nTPM]":"23.7","Cell RNA - U-266\/70 [nTPM]":"75.5","Cell RNA - U-266\/84 [nTPM]":"184.3","Cell RNA - U-698 [nTPM]":"22.0","Cell RNA - U-87 MG [nTPM]":"89.5","Cell RNA - U-937 [nTPM]":"61.3","Cell RNA - WM-115 [nTPM]":"24.6","Blood RNA - basophil [nTPM]":"285.2","Blood RNA - classical monocyte [nTPM]":"455.4","Blood RNA - eosinophil [nTPM]":"318.7","Blood RNA - gdT-cell [nTPM]":"47.6","Blood RNA - intermediate monocyte [nTPM]":"676.4","Blood RNA - MAIT T-cell [nTPM]":"43.1","Blood RNA - memory B-cell [nTPM]":"83.9","Blood RNA - memory CD4 T-cell [nTPM]":"35.5","Blood RNA - memory CD8 T-cell [nTPM]":"36.1","Blood RNA - myeloid DC [nTPM]":"175.1","Blood RNA - naive B-cell [nTPM]":"65.9","Blood RNA - naive CD4 T-cell [nTPM]":"40.8","Blood RNA - naive CD8 T-cell [nTPM]":"37.9","Blood RNA - neutrophil [nTPM]":"627.6","Blood RNA - NK-cell [nTPM]":"60.5","Blood RNA - non-classical monocyte [nTPM]":"731.4","Blood RNA - plasmacytoid DC [nTPM]":"33.0","Blood RNA - T-reg [nTPM]":"43.7","Blood RNA - total PBMC [nTPM]":"407.2","Brain RNA - amygdala [nTPM]":"50.1","Brain RNA - basal ganglia [nTPM]":"51.5","Brain RNA - cerebellum [nTPM]":"62.1","Brain RNA - cerebral cortex [nTPM]":"50.8","Brain RNA - hippocampal formation [nTPM]":"49.9","Brain RNA - hypothalamus [nTPM]":"66.2","Brain RNA - medulla oblongata [nTPM]":"66.0","Brain RNA - midbrain [nTPM]":"59.4","Brain RNA - pons [nTPM]":"69.0","Brain RNA - spinal cord [nTPM]":"66.3","Brain RNA - thalamus [nTPM]":"59.1","Brain RNA - white matter [nTPM]":"102.2","Single Cell Type RNA - Adipocytes [nTPM]":"98.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"317.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"405.0","Single Cell Type RNA - Astrocytes [nTPM]":"36.9","Single Cell Type RNA - B-cells [nTPM]":"92.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"58.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"83.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"103.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"35.3","Single Cell Type RNA - Bipolar cells [nTPM]":"97.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"105.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"87.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"777.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"100.1","Single Cell Type RNA - Club cells [nTPM]":"280.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"450.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"177.4","Single Cell Type RNA - dendritic cells [nTPM]":"67.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"83.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"60.7","Single Cell Type RNA - Ductal cells [nTPM]":"150.6","Single Cell Type RNA - Early spermatids [nTPM]":"2.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"85.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"51.5","Single Cell Type RNA - Endothelial cells [nTPM]":"79.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"98.1","Single Cell Type RNA - Erythroid cells [nTPM]":"106.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"49.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"104.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"65.2","Single Cell Type RNA - Fibroblasts [nTPM]":"122.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"43.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"133.8","Single Cell Type RNA - granulocytes [nTPM]":"257.0","Single Cell Type RNA - Granulosa cells [nTPM]":"49.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"134.6","Single Cell Type RNA - Hepatocytes [nTPM]":"50.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"921.2","Single Cell Type RNA - Horizontal cells [nTPM]":"77.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"53.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"99.3","Single Cell Type RNA - Ionocytes [nTPM]":"201.4","Single Cell Type RNA - Kupffer cells [nTPM]":"564.3","Single Cell Type RNA - Langerhans cells [nTPM]":"89.9","Single Cell Type RNA - Late spermatids [nTPM]":"6.0","Single Cell Type RNA - Leydig cells [nTPM]":"88.6","Single Cell Type RNA - Macrophages [nTPM]":"524.6","Single Cell Type RNA - Melanocytes [nTPM]":"318.4","Single Cell Type RNA - Microglial cells [nTPM]":"56.2","Single Cell Type RNA - monocytes [nTPM]":"259.2","Single Cell Type RNA - Muller glia cells [nTPM]":"532.6","Single Cell Type RNA - NK-cells [nTPM]":"53.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"49.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"49.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"64.7","Single Cell Type RNA - Paneth cells [nTPM]":"125.5","Single Cell Type RNA - Peritubular cells [nTPM]":"105.7","Single Cell Type RNA - Plasma cells [nTPM]":"87.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"87.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"77.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"304.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"147.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"88.0","Single Cell Type RNA - Sertoli cells [nTPM]":"177.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"74.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"157.0","Single Cell Type RNA - Spermatocytes [nTPM]":"14.0","Single Cell Type RNA - Spermatogonia [nTPM]":"63.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"84.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"64.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"148.2","Single Cell Type RNA - T-cells [nTPM]":"61.3","Single Cell Type RNA - Theca cells [nTPM]":"53.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"89.7","Single Cell Type RNA - Urothelial cells [nTPM]":"139.9"},{"Gene":"ASH1L","Gene synonym":["ASH1","ASH1L1","huASH1","KMT2H"],"Ensembl":"ENSG00000116539","Gene description":"ASH1 like histone lysine methyltransferase","Uniprot":["Q9NR48"],"Chromosome":"1","Position":"155335268-155563162","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","Chromatin regulator","Methyltransferase","Transferase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004806"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA004806":"AB_1845087"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.80e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Tissue RNA - adipose tissue [nTPM]":"14.1","Tissue RNA - adrenal gland [nTPM]":"12.8","Tissue RNA - amygdala [nTPM]":"21.3","Tissue RNA - appendix [nTPM]":"8.5","Tissue RNA - basal ganglia [nTPM]":"23.4","Tissue RNA - bone marrow [nTPM]":"11.9","Tissue RNA - breast [nTPM]":"16.8","Tissue RNA - cerebellum [nTPM]":"27.0","Tissue RNA - cerebral cortex [nTPM]":"25.7","Tissue RNA - cervix [nTPM]":"14.4","Tissue RNA - choroid plexus [nTPM]":"14.8","Tissue RNA - colon [nTPM]":"13.0","Tissue RNA - duodenum [nTPM]":"9.7","Tissue RNA - endometrium 1 [nTPM]":"14.4","Tissue RNA - epididymis [nTPM]":"20.8","Tissue RNA - esophagus [nTPM]":"9.2","Tissue RNA - fallopian tube [nTPM]":"11.4","Tissue RNA - gallbladder [nTPM]":"9.0","Tissue RNA - heart muscle [nTPM]":"12.6","Tissue RNA - hippocampal formation [nTPM]":"23.8","Tissue RNA - hypothalamus [nTPM]":"19.2","Tissue RNA - kidney [nTPM]":"13.9","Tissue RNA - liver [nTPM]":"10.0","Tissue RNA - lung [nTPM]":"10.3","Tissue RNA - lymph node [nTPM]":"10.9","Tissue RNA - medulla oblongata [nTPM]":"18.7","Tissue RNA - midbrain [nTPM]":"19.8","Tissue RNA - ovary [nTPM]":"21.3","Tissue RNA - pancreas [nTPM]":"9.9","Tissue RNA - parathyroid gland [nTPM]":"18.2","Tissue RNA - pituitary gland [nTPM]":"8.4","Tissue RNA - placenta [nTPM]":"10.3","Tissue RNA - pons [nTPM]":"18.9","Tissue RNA - prostate [nTPM]":"15.7","Tissue RNA - rectum [nTPM]":"11.5","Tissue RNA - retina [nTPM]":"26.2","Tissue RNA - salivary gland [nTPM]":"14.8","Tissue RNA - seminal vesicle [nTPM]":"15.4","Tissue RNA - skeletal muscle [nTPM]":"30.3","Tissue RNA - skin 1 [nTPM]":"20.4","Tissue RNA - small intestine [nTPM]":"10.2","Tissue RNA - smooth muscle [nTPM]":"12.7","Tissue RNA - spinal cord [nTPM]":"19.3","Tissue RNA - spleen [nTPM]":"10.5","Tissue RNA - stomach 1 [nTPM]":"11.9","Tissue RNA - testis [nTPM]":"6.8","Tissue RNA - thalamus [nTPM]":"20.7","Tissue RNA - thymus [nTPM]":"12.1","Tissue RNA - thyroid gland [nTPM]":"15.8","Tissue RNA - tongue [nTPM]":"24.3","Tissue RNA - tonsil [nTPM]":"9.7","Tissue RNA - urinary bladder [nTPM]":"11.7","Tissue RNA - vagina [nTPM]":"10.0","Tissue RNA - white matter [nTPM]":"23.4","Cell RNA - A-431 [nTPM]":"17.2","Cell RNA - A549 [nTPM]":"12.3","Cell RNA - AF22 [nTPM]":"9.5","Cell RNA - AN3-CA [nTPM]":"9.4","Cell RNA - ASC diff [nTPM]":"28.0","Cell RNA - ASC TERT1 [nTPM]":"22.8","Cell RNA - BEWO [nTPM]":"9.6","Cell RNA - BJ [nTPM]":"14.7","Cell RNA - BJ hTERT+ [nTPM]":"13.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.5","Cell RNA - CACO-2 [nTPM]":"10.5","Cell RNA - CAPAN-2 [nTPM]":"12.3","Cell RNA - Daudi [nTPM]":"5.4","Cell RNA - EFO-21 [nTPM]":"14.2","Cell RNA - fHDF\/TERT166 [nTPM]":"17.0","Cell RNA - GAMG [nTPM]":"5.4","Cell RNA - HaCaT [nTPM]":"19.2","Cell RNA - HAP1 [nTPM]":"13.6","Cell RNA - HBEC3-KT [nTPM]":"12.6","Cell RNA - HBF TERT88 [nTPM]":"13.6","Cell RNA - HDLM-2 [nTPM]":"7.6","Cell RNA - HEK 293 [nTPM]":"8.9","Cell RNA - HEL [nTPM]":"8.0","Cell RNA - HeLa [nTPM]":"13.2","Cell RNA - Hep G2 [nTPM]":"9.8","Cell RNA - HHSteC [nTPM]":"14.5","Cell RNA - HL-60 [nTPM]":"8.8","Cell RNA - HMC-1 [nTPM]":"6.6","Cell RNA - HSkMC [nTPM]":"16.2","Cell RNA - hTCEpi [nTPM]":"18.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.6","Cell RNA - hTERT-HME1 [nTPM]":"15.0","Cell RNA - hTERT-RPE1 [nTPM]":"17.1","Cell RNA - HUVEC TERT2 [nTPM]":"11.0","Cell RNA - JURKAT [nTPM]":"6.0","Cell RNA - K-562 [nTPM]":"12.3","Cell RNA - Karpas-707 [nTPM]":"8.3","Cell RNA - LHCN-M2 [nTPM]":"18.8","Cell RNA - MCF7 [nTPM]":"19.0","Cell RNA - MOLT-4 [nTPM]":"6.4","Cell RNA - NB-4 [nTPM]":"8.8","Cell RNA - NTERA-2 [nTPM]":"8.3","Cell RNA - OE19 [nTPM]":"28.8","Cell RNA - PC-3 [nTPM]":"13.1","Cell RNA - REH [nTPM]":"6.1","Cell RNA - RH-30 [nTPM]":"18.5","Cell RNA - RPMI-8226 [nTPM]":"10.4","Cell RNA - RPTEC TERT1 [nTPM]":"18.6","Cell RNA - RT4 [nTPM]":"16.0","Cell RNA - SCLC-21H [nTPM]":"9.1","Cell RNA - SH-SY5Y [nTPM]":"14.3","Cell RNA - SiHa [nTPM]":"20.1","Cell RNA - SK-BR-3 [nTPM]":"25.9","Cell RNA - SK-MEL-30 [nTPM]":"12.9","Cell RNA - SuSa [nTPM]":"9.3","Cell RNA - T-47d [nTPM]":"16.6","Cell RNA - THP-1 [nTPM]":"26.6","Cell RNA - TIME [nTPM]":"17.4","Cell RNA - U-138 MG [nTPM]":"13.6","Cell RNA - U-2 OS [nTPM]":"15.8","Cell RNA - U-2197 [nTPM]":"13.4","Cell RNA - U-251 MG [nTPM]":"17.9","Cell RNA - U-266\/70 [nTPM]":"8.0","Cell RNA - U-266\/84 [nTPM]":"5.3","Cell RNA - U-698 [nTPM]":"8.9","Cell RNA - U-87 MG [nTPM]":"10.7","Cell RNA - U-937 [nTPM]":"9.1","Cell RNA - WM-115 [nTPM]":"13.1","Blood RNA - basophil [nTPM]":"1.0","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.8","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.8","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"0.9","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"21.3","Brain RNA - basal ganglia [nTPM]":"23.4","Brain RNA - cerebellum [nTPM]":"27.0","Brain RNA - cerebral cortex [nTPM]":"25.7","Brain RNA - hippocampal formation [nTPM]":"23.8","Brain RNA - hypothalamus [nTPM]":"19.2","Brain RNA - medulla oblongata [nTPM]":"18.7","Brain RNA - midbrain [nTPM]":"19.8","Brain RNA - pons [nTPM]":"18.9","Brain RNA - spinal cord [nTPM]":"19.3","Brain RNA - thalamus [nTPM]":"20.7","Brain RNA - white matter [nTPM]":"23.4","Single Cell Type RNA - Adipocytes [nTPM]":"96.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"103.2","Single Cell Type RNA - Astrocytes [nTPM]":"171.7","Single Cell Type RNA - B-cells [nTPM]":"108.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"103.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"97.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"52.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"109.3","Single Cell Type RNA - Bipolar cells [nTPM]":"147.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"75.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"58.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"107.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"50.1","Single Cell Type RNA - Club cells [nTPM]":"82.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"51.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"202.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"53.6","Single Cell Type RNA - dendritic cells [nTPM]":"83.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"76.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"41.5","Single Cell Type RNA - Early spermatids [nTPM]":"25.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"72.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"107.4","Single Cell Type RNA - Endothelial cells [nTPM]":"77.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"67.5","Single Cell Type RNA - Erythroid cells [nTPM]":"46.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"220.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"39.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"25.2","Single Cell Type RNA - Fibroblasts [nTPM]":"93.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"101.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"87.9","Single Cell Type RNA - granulocytes [nTPM]":"81.1","Single Cell Type RNA - Granulosa cells [nTPM]":"72.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"63.1","Single Cell Type RNA - Hepatocytes [nTPM]":"39.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.6","Single Cell Type RNA - Horizontal cells [nTPM]":"114.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"211.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"59.0","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"42.1","Single Cell Type RNA - Langerhans cells [nTPM]":"106.9","Single Cell Type RNA - Late spermatids [nTPM]":"22.8","Single Cell Type RNA - Leydig cells [nTPM]":"102.2","Single Cell Type RNA - Macrophages [nTPM]":"69.1","Single Cell Type RNA - Melanocytes [nTPM]":"53.4","Single Cell Type RNA - Microglial cells [nTPM]":"203.3","Single Cell Type RNA - monocytes [nTPM]":"85.2","Single Cell Type RNA - Muller glia cells [nTPM]":"68.4","Single Cell Type RNA - NK-cells [nTPM]":"89.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"190.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"265.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"37.5","Single Cell Type RNA - Paneth cells [nTPM]":"64.8","Single Cell Type RNA - Peritubular cells [nTPM]":"118.8","Single Cell Type RNA - Plasma cells [nTPM]":"110.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"112.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"68.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"31.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"47.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"116.7","Single Cell Type RNA - Sertoli cells [nTPM]":"98.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"134.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"104.6","Single Cell Type RNA - Spermatocytes [nTPM]":"85.6","Single Cell Type RNA - Spermatogonia [nTPM]":"56.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"80.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"112.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"76.2","Single Cell Type RNA - T-cells [nTPM]":"98.7","Single Cell Type RNA - Theca cells [nTPM]":"87.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"60.2","Single Cell Type RNA - Urothelial cells [nTPM]":"111.6"},{"Gene":"ASL","Gene synonym":["ASAL"],"Ensembl":"ENSG00000126522","Gene description":"Argininosuccinate lyase","Uniprot":["P04424"],"Chromosome":"7","Position":"66075800-66094697","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Amino-acid biosynthesis","Arginine biosynthesis","Urea cycle"],"Molecular function":["Lyase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"liver":"396.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"294.6","Exocrine glandular cells":"218.6","Hepatocytes":"578.0","Paneth cells":"240.4","Proximal enterocytes":"259.9","Proximal tubular cells":"243.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"52.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003696","HPA016646"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB003696":"AB_425316","HPA016646":"AB_1845096"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.05e-6"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.40e-3"},"Tissue RNA - adipose tissue [nTPM]":"21.7","Tissue RNA - adrenal gland [nTPM]":"16.1","Tissue RNA - amygdala [nTPM]":"5.9","Tissue RNA - appendix [nTPM]":"16.7","Tissue RNA - basal ganglia [nTPM]":"6.0","Tissue RNA - bone marrow [nTPM]":"23.9","Tissue RNA - breast [nTPM]":"22.0","Tissue RNA - cerebellum [nTPM]":"6.6","Tissue RNA - cerebral cortex [nTPM]":"8.5","Tissue RNA - cervix [nTPM]":"18.2","Tissue RNA - choroid plexus [nTPM]":"8.7","Tissue RNA - colon [nTPM]":"53.8","Tissue RNA - duodenum [nTPM]":"60.7","Tissue RNA - endometrium 1 [nTPM]":"17.0","Tissue RNA - epididymis [nTPM]":"6.7","Tissue RNA - esophagus [nTPM]":"28.7","Tissue RNA - fallopian tube [nTPM]":"18.1","Tissue RNA - gallbladder [nTPM]":"27.7","Tissue RNA - heart muscle [nTPM]":"16.9","Tissue RNA - hippocampal formation [nTPM]":"5.9","Tissue RNA - hypothalamus [nTPM]":"8.0","Tissue RNA - kidney [nTPM]":"61.2","Tissue RNA - liver [nTPM]":"396.4","Tissue RNA - lung [nTPM]":"27.4","Tissue RNA - lymph node [nTPM]":"10.3","Tissue RNA - medulla oblongata [nTPM]":"7.4","Tissue RNA - midbrain [nTPM]":"7.1","Tissue RNA - ovary [nTPM]":"19.7","Tissue RNA - pancreas [nTPM]":"37.1","Tissue RNA - parathyroid gland [nTPM]":"15.1","Tissue RNA - pituitary gland [nTPM]":"19.8","Tissue RNA - placenta [nTPM]":"9.1","Tissue RNA - pons [nTPM]":"9.8","Tissue RNA - prostate [nTPM]":"19.5","Tissue RNA - rectum [nTPM]":"35.7","Tissue RNA - retina [nTPM]":"2.4","Tissue RNA - salivary gland [nTPM]":"18.3","Tissue RNA - seminal vesicle [nTPM]":"9.8","Tissue RNA - skeletal muscle [nTPM]":"8.7","Tissue RNA - skin 1 [nTPM]":"15.1","Tissue RNA - small intestine [nTPM]":"45.6","Tissue RNA - smooth muscle [nTPM]":"10.1","Tissue RNA - spinal cord [nTPM]":"6.2","Tissue RNA - spleen [nTPM]":"30.5","Tissue RNA - stomach 1 [nTPM]":"43.9","Tissue RNA - testis [nTPM]":"4.5","Tissue RNA - thalamus [nTPM]":"7.6","Tissue RNA - thymus [nTPM]":"5.3","Tissue RNA - thyroid gland [nTPM]":"24.9","Tissue RNA - tongue [nTPM]":"6.9","Tissue RNA - tonsil [nTPM]":"8.8","Tissue RNA - urinary bladder [nTPM]":"19.3","Tissue RNA - vagina [nTPM]":"19.8","Tissue RNA - white matter [nTPM]":"6.7","Cell RNA - A-431 [nTPM]":"48.4","Cell RNA - A549 [nTPM]":"18.9","Cell RNA - AF22 [nTPM]":"11.2","Cell RNA - AN3-CA [nTPM]":"36.7","Cell RNA - ASC diff [nTPM]":"26.3","Cell RNA - ASC TERT1 [nTPM]":"18.1","Cell RNA - BEWO [nTPM]":"22.1","Cell RNA - BJ [nTPM]":"34.0","Cell RNA - BJ hTERT+ [nTPM]":"31.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"49.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"43.6","Cell RNA - CACO-2 [nTPM]":"43.7","Cell RNA - CAPAN-2 [nTPM]":"59.0","Cell RNA - Daudi [nTPM]":"15.9","Cell RNA - EFO-21 [nTPM]":"53.7","Cell RNA - fHDF\/TERT166 [nTPM]":"48.5","Cell RNA - GAMG [nTPM]":"36.6","Cell RNA - HaCaT [nTPM]":"13.4","Cell RNA - HAP1 [nTPM]":"7.1","Cell RNA - HBEC3-KT [nTPM]":"59.1","Cell RNA - HBF TERT88 [nTPM]":"11.1","Cell RNA - HDLM-2 [nTPM]":"10.5","Cell RNA - HEK 293 [nTPM]":"8.9","Cell RNA - HEL [nTPM]":"18.8","Cell RNA - HeLa [nTPM]":"17.9","Cell RNA - Hep G2 [nTPM]":"77.2","Cell RNA - HHSteC [nTPM]":"48.8","Cell RNA - HL-60 [nTPM]":"24.0","Cell RNA - HMC-1 [nTPM]":"51.3","Cell RNA - HSkMC [nTPM]":"38.3","Cell RNA - hTCEpi [nTPM]":"19.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"31.8","Cell RNA - hTERT-HME1 [nTPM]":"51.8","Cell RNA - hTERT-RPE1 [nTPM]":"12.5","Cell RNA - HUVEC TERT2 [nTPM]":"48.1","Cell RNA - JURKAT [nTPM]":"11.3","Cell RNA - K-562 [nTPM]":"34.4","Cell RNA - Karpas-707 [nTPM]":"27.8","Cell RNA - LHCN-M2 [nTPM]":"25.4","Cell RNA - MCF7 [nTPM]":"36.6","Cell RNA - MOLT-4 [nTPM]":"4.8","Cell RNA - NB-4 [nTPM]":"28.9","Cell RNA - NTERA-2 [nTPM]":"15.8","Cell RNA - OE19 [nTPM]":"65.5","Cell RNA - PC-3 [nTPM]":"26.1","Cell RNA - REH [nTPM]":"12.1","Cell RNA - RH-30 [nTPM]":"11.0","Cell RNA - RPMI-8226 [nTPM]":"51.6","Cell RNA - RPTEC TERT1 [nTPM]":"31.9","Cell RNA - RT4 [nTPM]":"31.6","Cell RNA - SCLC-21H [nTPM]":"18.4","Cell RNA - SH-SY5Y [nTPM]":"24.3","Cell RNA - SiHa [nTPM]":"32.3","Cell RNA - SK-BR-3 [nTPM]":"109.7","Cell RNA - SK-MEL-30 [nTPM]":"12.3","Cell RNA - SuSa [nTPM]":"11.4","Cell RNA - T-47d [nTPM]":"46.0","Cell RNA - THP-1 [nTPM]":"19.7","Cell RNA - TIME [nTPM]":"55.1","Cell RNA - U-138 MG [nTPM]":"53.7","Cell RNA - U-2 OS [nTPM]":"30.8","Cell RNA - U-2197 [nTPM]":"23.5","Cell RNA - U-251 MG [nTPM]":"45.2","Cell RNA - U-266\/70 [nTPM]":"30.2","Cell RNA - U-266\/84 [nTPM]":"16.9","Cell RNA - U-698 [nTPM]":"19.0","Cell RNA - U-87 MG [nTPM]":"55.0","Cell RNA - U-937 [nTPM]":"41.5","Cell RNA - WM-115 [nTPM]":"49.5","Blood RNA - basophil [nTPM]":"34.2","Blood RNA - classical monocyte [nTPM]":"42.6","Blood RNA - eosinophil [nTPM]":"50.8","Blood RNA - gdT-cell [nTPM]":"16.9","Blood RNA - intermediate monocyte [nTPM]":"46.6","Blood RNA - MAIT T-cell [nTPM]":"15.1","Blood RNA - memory B-cell [nTPM]":"21.8","Blood RNA - memory CD4 T-cell [nTPM]":"11.5","Blood RNA - memory CD8 T-cell [nTPM]":"13.4","Blood RNA - myeloid DC [nTPM]":"46.2","Blood RNA - naive B-cell [nTPM]":"13.8","Blood RNA - naive CD4 T-cell [nTPM]":"8.2","Blood RNA - naive CD8 T-cell [nTPM]":"8.5","Blood RNA - neutrophil [nTPM]":"7.3","Blood RNA - NK-cell [nTPM]":"73.7","Blood RNA - non-classical monocyte [nTPM]":"36.1","Blood RNA - plasmacytoid DC [nTPM]":"2.5","Blood RNA - T-reg [nTPM]":"23.4","Blood RNA - total PBMC [nTPM]":"27.3","Brain RNA - amygdala [nTPM]":"5.9","Brain RNA - basal ganglia [nTPM]":"6.0","Brain RNA - cerebellum [nTPM]":"6.6","Brain RNA - cerebral cortex [nTPM]":"8.5","Brain RNA - hippocampal formation [nTPM]":"5.9","Brain RNA - hypothalamus [nTPM]":"8.0","Brain RNA - medulla oblongata [nTPM]":"7.4","Brain RNA - midbrain [nTPM]":"7.1","Brain RNA - pons [nTPM]":"9.8","Brain RNA - spinal cord [nTPM]":"6.2","Brain RNA - thalamus [nTPM]":"7.6","Brain RNA - white matter [nTPM]":"6.7","Single Cell Type RNA - Adipocytes [nTPM]":"34.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"61.4","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"20.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"24.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"12.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"24.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"124.4","Single Cell Type RNA - Club cells [nTPM]":"25.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.7","Single Cell Type RNA - dendritic cells [nTPM]":"25.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"294.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"52.8","Single Cell Type RNA - Ductal cells [nTPM]":"73.7","Single Cell Type RNA - Early spermatids [nTPM]":"4.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"41.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.1","Single Cell Type RNA - Endothelial cells [nTPM]":"30.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"54.0","Single Cell Type RNA - Erythroid cells [nTPM]":"47.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"218.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"45.7","Single Cell Type RNA - Fibroblasts [nTPM]":"14.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"115.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"34.1","Single Cell Type RNA - granulocytes [nTPM]":"44.5","Single Cell Type RNA - Granulosa cells [nTPM]":"12.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"42.8","Single Cell Type RNA - Hepatocytes [nTPM]":"578.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"46.0","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"126.5","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"41.2","Single Cell Type RNA - Langerhans cells [nTPM]":"17.6","Single Cell Type RNA - Late spermatids [nTPM]":"6.3","Single Cell Type RNA - Leydig cells [nTPM]":"9.3","Single Cell Type RNA - Macrophages [nTPM]":"22.3","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"48.3","Single Cell Type RNA - Muller glia cells [nTPM]":"7.2","Single Cell Type RNA - NK-cells [nTPM]":"34.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"118.3","Single Cell Type RNA - Paneth cells [nTPM]":"240.4","Single Cell Type RNA - Peritubular cells [nTPM]":"8.2","Single Cell Type RNA - Plasma cells [nTPM]":"23.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"259.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"243.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"42.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.5","Single Cell Type RNA - Spermatocytes [nTPM]":"3.2","Single Cell Type RNA - Spermatogonia [nTPM]":"5.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.3","Single Cell Type RNA - T-cells [nTPM]":"18.0","Single Cell Type RNA - Theca cells [nTPM]":"13.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"189.4","Single Cell Type RNA - Urothelial cells [nTPM]":"22.0"},{"Gene":"ASNS","Gene synonym":[],"Ensembl":"ENSG00000070669","Gene description":"Asparagine synthetase (glutamine-hydrolyzing)","Uniprot":["P08243"],"Chromosome":"7","Position":"97851677-97872542","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Amino-acid biosynthesis","Asparagine biosynthesis"],"Molecular function":["Ligase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"121.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"233.9","Late spermatids":"217.0","Smooth muscle cells":"112.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"B-cells":"8.9","T-cells":"14.2"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004924","HPA029318","HPA064737"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"47000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA004924":"AB_2667295","HPA029318":"AB_10602389","HPA064737":"AB_2685341"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.24e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.79e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.42e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.21e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Tissue RNA - adipose tissue [nTPM]":"17.3","Tissue RNA - adrenal gland [nTPM]":"18.0","Tissue RNA - amygdala [nTPM]":"49.9","Tissue RNA - appendix [nTPM]":"19.5","Tissue RNA - basal ganglia [nTPM]":"52.3","Tissue RNA - bone marrow [nTPM]":"13.7","Tissue RNA - breast [nTPM]":"17.8","Tissue RNA - cerebellum [nTPM]":"52.7","Tissue RNA - cerebral cortex [nTPM]":"66.3","Tissue RNA - cervix [nTPM]":"19.9","Tissue RNA - choroid plexus [nTPM]":"28.2","Tissue RNA - colon [nTPM]":"24.5","Tissue RNA - duodenum [nTPM]":"9.7","Tissue RNA - endometrium 1 [nTPM]":"19.0","Tissue RNA - epididymis [nTPM]":"31.5","Tissue RNA - esophagus [nTPM]":"27.0","Tissue RNA - fallopian tube [nTPM]":"20.1","Tissue RNA - gallbladder [nTPM]":"11.2","Tissue RNA - heart muscle [nTPM]":"19.4","Tissue RNA - hippocampal formation [nTPM]":"55.3","Tissue RNA - hypothalamus [nTPM]":"51.0","Tissue RNA - kidney [nTPM]":"28.9","Tissue RNA - liver [nTPM]":"9.3","Tissue RNA - lung [nTPM]":"25.6","Tissue RNA - lymph node [nTPM]":"28.8","Tissue RNA - medulla oblongata [nTPM]":"58.7","Tissue RNA - midbrain [nTPM]":"43.5","Tissue RNA - ovary [nTPM]":"20.8","Tissue RNA - pancreas [nTPM]":"121.4","Tissue RNA - parathyroid gland [nTPM]":"26.3","Tissue RNA - pituitary gland [nTPM]":"44.1","Tissue RNA - placenta [nTPM]":"4.6","Tissue RNA - pons [nTPM]":"59.4","Tissue RNA - prostate [nTPM]":"21.5","Tissue RNA - rectum [nTPM]":"19.9","Tissue RNA - retina [nTPM]":"35.3","Tissue RNA - salivary gland [nTPM]":"41.6","Tissue RNA - seminal vesicle [nTPM]":"14.5","Tissue RNA - skeletal muscle [nTPM]":"8.0","Tissue RNA - skin 1 [nTPM]":"22.9","Tissue RNA - small intestine [nTPM]":"22.6","Tissue RNA - smooth muscle [nTPM]":"18.0","Tissue RNA - spinal cord [nTPM]":"43.6","Tissue RNA - spleen [nTPM]":"30.3","Tissue RNA - stomach 1 [nTPM]":"46.0","Tissue RNA - testis [nTPM]":"33.3","Tissue RNA - thalamus [nTPM]":"49.7","Tissue RNA - thymus [nTPM]":"13.3","Tissue RNA - thyroid gland [nTPM]":"27.5","Tissue RNA - tongue [nTPM]":"8.6","Tissue RNA - tonsil [nTPM]":"25.7","Tissue RNA - urinary bladder [nTPM]":"21.7","Tissue RNA - vagina [nTPM]":"18.6","Tissue RNA - white matter [nTPM]":"63.8","Cell RNA - A-431 [nTPM]":"124.6","Cell RNA - A549 [nTPM]":"46.6","Cell RNA - AF22 [nTPM]":"51.6","Cell RNA - AN3-CA [nTPM]":"415.9","Cell RNA - ASC diff [nTPM]":"35.3","Cell RNA - ASC TERT1 [nTPM]":"57.9","Cell RNA - BEWO [nTPM]":"109.1","Cell RNA - BJ [nTPM]":"85.7","Cell RNA - BJ hTERT+ [nTPM]":"62.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"41.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"134.8","Cell RNA - CACO-2 [nTPM]":"64.2","Cell RNA - CAPAN-2 [nTPM]":"49.3","Cell RNA - Daudi [nTPM]":"101.7","Cell RNA - EFO-21 [nTPM]":"45.3","Cell RNA - fHDF\/TERT166 [nTPM]":"189.8","Cell RNA - GAMG [nTPM]":"92.3","Cell RNA - HaCaT [nTPM]":"57.4","Cell RNA - HAP1 [nTPM]":"118.2","Cell RNA - HBEC3-KT [nTPM]":"151.2","Cell RNA - HBF TERT88 [nTPM]":"102.2","Cell RNA - HDLM-2 [nTPM]":"122.4","Cell RNA - HEK 293 [nTPM]":"85.3","Cell RNA - HEL [nTPM]":"31.0","Cell RNA - HeLa [nTPM]":"24.6","Cell RNA - Hep G2 [nTPM]":"50.8","Cell RNA - HHSteC [nTPM]":"347.8","Cell RNA - HL-60 [nTPM]":"207.1","Cell RNA - HMC-1 [nTPM]":"89.9","Cell RNA - HSkMC [nTPM]":"106.2","Cell RNA - hTCEpi [nTPM]":"508.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"55.8","Cell RNA - hTERT-HME1 [nTPM]":"361.2","Cell RNA - hTERT-RPE1 [nTPM]":"23.5","Cell RNA - HUVEC TERT2 [nTPM]":"41.4","Cell RNA - JURKAT [nTPM]":"94.4","Cell RNA - K-562 [nTPM]":"177.1","Cell RNA - Karpas-707 [nTPM]":"365.2","Cell RNA - LHCN-M2 [nTPM]":"76.3","Cell RNA - MCF7 [nTPM]":"286.5","Cell RNA - MOLT-4 [nTPM]":"6.4","Cell RNA - NB-4 [nTPM]":"54.4","Cell RNA - NTERA-2 [nTPM]":"68.1","Cell RNA - OE19 [nTPM]":"308.4","Cell RNA - PC-3 [nTPM]":"125.4","Cell RNA - REH [nTPM]":"14.0","Cell RNA - RH-30 [nTPM]":"10.0","Cell RNA - RPMI-8226 [nTPM]":"282.7","Cell RNA - RPTEC TERT1 [nTPM]":"28.4","Cell RNA - RT4 [nTPM]":"22.3","Cell RNA - SCLC-21H [nTPM]":"218.1","Cell RNA - SH-SY5Y [nTPM]":"156.7","Cell RNA - SiHa [nTPM]":"23.2","Cell RNA - SK-BR-3 [nTPM]":"136.7","Cell RNA - SK-MEL-30 [nTPM]":"499.0","Cell RNA - SuSa [nTPM]":"60.6","Cell RNA - T-47d [nTPM]":"57.1","Cell RNA - THP-1 [nTPM]":"139.1","Cell RNA - TIME [nTPM]":"7.6","Cell RNA - U-138 MG [nTPM]":"21.6","Cell RNA - U-2 OS [nTPM]":"138.5","Cell RNA - U-2197 [nTPM]":"56.7","Cell RNA - U-251 MG [nTPM]":"40.7","Cell RNA - U-266\/70 [nTPM]":"412.6","Cell RNA - U-266\/84 [nTPM]":"239.7","Cell RNA - U-698 [nTPM]":"401.1","Cell RNA - U-87 MG [nTPM]":"288.7","Cell RNA - U-937 [nTPM]":"90.3","Cell RNA - WM-115 [nTPM]":"220.8","Blood RNA - basophil [nTPM]":"1.9","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"3.6","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"4.3","Blood RNA - memory B-cell [nTPM]":"8.9","Blood RNA - memory CD4 T-cell [nTPM]":"7.2","Blood RNA - memory CD8 T-cell [nTPM]":"3.4","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"6.0","Blood RNA - naive CD4 T-cell [nTPM]":"10.1","Blood RNA - naive CD8 T-cell [nTPM]":"5.5","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"2.0","Blood RNA - non-classical monocyte [nTPM]":"1.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"14.2","Blood RNA - total PBMC [nTPM]":"3.3","Brain RNA - amygdala [nTPM]":"49.9","Brain RNA - basal ganglia [nTPM]":"52.3","Brain RNA - cerebellum [nTPM]":"52.7","Brain RNA - cerebral cortex [nTPM]":"66.3","Brain RNA - hippocampal formation [nTPM]":"55.3","Brain RNA - hypothalamus [nTPM]":"51.0","Brain RNA - medulla oblongata [nTPM]":"58.7","Brain RNA - midbrain [nTPM]":"43.5","Brain RNA - pons [nTPM]":"59.4","Brain RNA - spinal cord [nTPM]":"43.6","Brain RNA - thalamus [nTPM]":"49.7","Brain RNA - white matter [nTPM]":"63.8","Single Cell Type RNA - Adipocytes [nTPM]":"5.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.2","Single Cell Type RNA - Astrocytes [nTPM]":"11.1","Single Cell Type RNA - B-cells [nTPM]":"14.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"26.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"20.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"20.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"12.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.1","Single Cell Type RNA - dendritic cells [nTPM]":"6.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"30.9","Single Cell Type RNA - Early spermatids [nTPM]":"233.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.6","Single Cell Type RNA - Endothelial cells [nTPM]":"6.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"24.4","Single Cell Type RNA - Erythroid cells [nTPM]":"46.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"51.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"61.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.8","Single Cell Type RNA - Fibroblasts [nTPM]":"8.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.5","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"8.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.9","Single Cell Type RNA - Hepatocytes [nTPM]":"1.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.1","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"48.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.6","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"3.2","Single Cell Type RNA - Late spermatids [nTPM]":"217.0","Single Cell Type RNA - Leydig cells [nTPM]":"9.6","Single Cell Type RNA - Macrophages [nTPM]":"2.1","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"7.3","Single Cell Type RNA - Muller glia cells [nTPM]":"9.2","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"36.6","Single Cell Type RNA - Paneth cells [nTPM]":"14.7","Single Cell Type RNA - Peritubular cells [nTPM]":"9.4","Single Cell Type RNA - Plasma cells [nTPM]":"19.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"26.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"112.3","Single Cell Type RNA - Spermatocytes [nTPM]":"3.4","Single Cell Type RNA - Spermatogonia [nTPM]":"20.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.6","Single Cell Type RNA - T-cells [nTPM]":"11.2","Single Cell Type RNA - Theca cells [nTPM]":"6.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.9","Single Cell Type RNA - Urothelial cells [nTPM]":"14.9"},{"Gene":"ASPA","Gene synonym":["ACY2","ASP"],"Ensembl":"ENSG00000108381","Gene description":"Aspartoacylase","Uniprot":["P45381"],"Chromosome":"17","Position":"3472374-3503405","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Leukodystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"69.0","kidney":"38.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Leydig cells":"49.7","Melanocytes":"46.2","Oligodendrocytes":"217.0","Peritubular cells":"48.2","Proximal enterocytes":"37.5","Proximal tubular cells":"74.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"7.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"5.4","ASC TERT1":"4.1","CACO-2":"3.8","HSkMC":"7.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022142","HPA022145"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA022142":"AB_1845102","HPA022145":"AB_1845103"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Tissue RNA - adipose tissue [nTPM]":"13.9","Tissue RNA - adrenal gland [nTPM]":"4.3","Tissue RNA - amygdala [nTPM]":"25.9","Tissue RNA - appendix [nTPM]":"1.8","Tissue RNA - basal ganglia [nTPM]":"46.4","Tissue RNA - bone marrow [nTPM]":"1.8","Tissue RNA - breast [nTPM]":"4.1","Tissue RNA - cerebellum [nTPM]":"27.6","Tissue RNA - cerebral cortex [nTPM]":"40.9","Tissue RNA - cervix [nTPM]":"7.5","Tissue RNA - choroid plexus [nTPM]":"14.2","Tissue RNA - colon [nTPM]":"4.3","Tissue RNA - duodenum [nTPM]":"11.2","Tissue RNA - endometrium 1 [nTPM]":"4.5","Tissue RNA - epididymis [nTPM]":"6.0","Tissue RNA - esophagus [nTPM]":"4.9","Tissue RNA - fallopian tube [nTPM]":"5.5","Tissue RNA - gallbladder [nTPM]":"3.6","Tissue RNA - heart muscle [nTPM]":"2.7","Tissue RNA - hippocampal formation [nTPM]":"25.8","Tissue RNA - hypothalamus [nTPM]":"27.7","Tissue RNA - kidney [nTPM]":"38.2","Tissue RNA - liver [nTPM]":"15.0","Tissue RNA - lung [nTPM]":"3.5","Tissue RNA - lymph node [nTPM]":"1.5","Tissue RNA - medulla oblongata [nTPM]":"30.4","Tissue RNA - midbrain [nTPM]":"35.4","Tissue RNA - ovary [nTPM]":"2.9","Tissue RNA - pancreas [nTPM]":"1.0","Tissue RNA - parathyroid gland [nTPM]":"0.8","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"3.5","Tissue RNA - pons [nTPM]":"29.5","Tissue RNA - prostate [nTPM]":"4.1","Tissue RNA - rectum [nTPM]":"4.9","Tissue RNA - retina [nTPM]":"2.8","Tissue RNA - salivary gland [nTPM]":"1.8","Tissue RNA - seminal vesicle [nTPM]":"5.0","Tissue RNA - skeletal muscle [nTPM]":"11.9","Tissue RNA - skin 1 [nTPM]":"5.2","Tissue RNA - small intestine [nTPM]":"15.6","Tissue RNA - smooth muscle [nTPM]":"3.1","Tissue RNA - spinal cord [nTPM]":"24.7","Tissue RNA - spleen [nTPM]":"5.4","Tissue RNA - stomach 1 [nTPM]":"4.4","Tissue RNA - testis [nTPM]":"6.6","Tissue RNA - thalamus [nTPM]":"42.4","Tissue RNA - thymus [nTPM]":"0.6","Tissue RNA - thyroid gland [nTPM]":"2.1","Tissue RNA - tongue [nTPM]":"15.0","Tissue RNA - tonsil [nTPM]":"0.7","Tissue RNA - urinary bladder [nTPM]":"6.3","Tissue RNA - vagina [nTPM]":"4.3","Tissue RNA - white matter [nTPM]":"69.0","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"0.5","Cell RNA - ASC diff [nTPM]":"5.4","Cell RNA - ASC TERT1 [nTPM]":"4.1","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"3.8","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.6","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.7","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"2.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"0.7","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.5","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"7.5","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.4","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"1.1","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"1.1","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"1.1","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.9","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.6","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"1.1","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"25.9","Brain RNA - basal ganglia [nTPM]":"46.4","Brain RNA - cerebellum [nTPM]":"27.6","Brain RNA - cerebral cortex [nTPM]":"40.9","Brain RNA - hippocampal formation [nTPM]":"25.8","Brain RNA - hypothalamus [nTPM]":"27.7","Brain RNA - medulla oblongata [nTPM]":"30.4","Brain RNA - midbrain [nTPM]":"35.4","Brain RNA - pons [nTPM]":"29.5","Brain RNA - spinal cord [nTPM]":"24.7","Brain RNA - thalamus [nTPM]":"42.4","Brain RNA - white matter [nTPM]":"69.0","Single Cell Type RNA - Adipocytes [nTPM]":"5.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.5","Single Cell Type RNA - Astrocytes [nTPM]":"12.1","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"5.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"1.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"5.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"15.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"11.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.8","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"1.5","Single Cell Type RNA - Late spermatids [nTPM]":"2.5","Single Cell Type RNA - Leydig cells [nTPM]":"49.7","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"46.2","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"217.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"2.5","Single Cell Type RNA - Peritubular cells [nTPM]":"48.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"37.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"74.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.6","Single Cell Type RNA - Spermatocytes [nTPM]":"11.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"28.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.8","Single Cell Type RNA - Urothelial cells [nTPM]":"2.7"},{"Gene":"ASPH","Gene synonym":["BAH","CASQ2BP1","HAAH","JCTN"],"Ensembl":"ENSG00000198363","Gene description":"Aspartate beta-hydroxylase","Uniprot":["Q12797"],"Chromosome":"8","Position":"61500556-61714640","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Dioxygenase","Oxidoreductase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"386.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Muller glia cells":"468.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"34.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-87 MG":"890.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055161","HPA059303"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1100000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 5: Muller glia cells - Visual perception","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA055161":"AB_2682721","HPA059303":"AB_2683973"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.07e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.61e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.75e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.57e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.24e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Tissue RNA - adipose tissue [nTPM]":"386.9","Tissue RNA - adrenal gland [nTPM]":"160.3","Tissue RNA - amygdala [nTPM]":"64.7","Tissue RNA - appendix [nTPM]":"50.6","Tissue RNA - basal ganglia [nTPM]":"69.2","Tissue RNA - bone marrow [nTPM]":"16.9","Tissue RNA - breast [nTPM]":"106.9","Tissue RNA - cerebellum [nTPM]":"102.3","Tissue RNA - cerebral cortex [nTPM]":"88.9","Tissue RNA - cervix [nTPM]":"65.6","Tissue RNA - choroid plexus [nTPM]":"84.4","Tissue RNA - colon [nTPM]":"78.8","Tissue RNA - duodenum [nTPM]":"45.6","Tissue RNA - endometrium 1 [nTPM]":"49.3","Tissue RNA - epididymis [nTPM]":"44.7","Tissue RNA - esophagus [nTPM]":"71.4","Tissue RNA - fallopian tube [nTPM]":"46.9","Tissue RNA - gallbladder [nTPM]":"61.0","Tissue RNA - heart muscle [nTPM]":"111.3","Tissue RNA - hippocampal formation [nTPM]":"64.5","Tissue RNA - hypothalamus [nTPM]":"58.4","Tissue RNA - kidney [nTPM]":"59.5","Tissue RNA - liver [nTPM]":"74.9","Tissue RNA - lung [nTPM]":"74.1","Tissue RNA - lymph node [nTPM]":"20.3","Tissue RNA - medulla oblongata [nTPM]":"54.0","Tissue RNA - midbrain [nTPM]":"69.2","Tissue RNA - ovary [nTPM]":"62.2","Tissue RNA - pancreas [nTPM]":"44.7","Tissue RNA - parathyroid gland [nTPM]":"38.7","Tissue RNA - pituitary gland [nTPM]":"36.3","Tissue RNA - placenta [nTPM]":"47.9","Tissue RNA - pons [nTPM]":"52.2","Tissue RNA - prostate [nTPM]":"48.3","Tissue RNA - rectum [nTPM]":"84.9","Tissue RNA - retina [nTPM]":"219.5","Tissue RNA - salivary gland [nTPM]":"101.9","Tissue RNA - seminal vesicle [nTPM]":"70.2","Tissue RNA - skeletal muscle [nTPM]":"357.6","Tissue RNA - skin 1 [nTPM]":"35.2","Tissue RNA - small intestine [nTPM]":"45.5","Tissue RNA - smooth muscle [nTPM]":"67.5","Tissue RNA - spinal cord [nTPM]":"44.8","Tissue RNA - spleen [nTPM]":"28.6","Tissue RNA - stomach 1 [nTPM]":"105.0","Tissue RNA - testis [nTPM]":"16.5","Tissue RNA - thalamus [nTPM]":"71.8","Tissue RNA - thymus [nTPM]":"16.7","Tissue RNA - thyroid gland [nTPM]":"97.0","Tissue RNA - tongue [nTPM]":"182.7","Tissue RNA - tonsil [nTPM]":"28.5","Tissue RNA - urinary bladder [nTPM]":"112.2","Tissue RNA - vagina [nTPM]":"43.8","Tissue RNA - white matter [nTPM]":"60.4","Cell RNA - A-431 [nTPM]":"460.3","Cell RNA - A549 [nTPM]":"652.3","Cell RNA - AF22 [nTPM]":"89.9","Cell RNA - AN3-CA [nTPM]":"55.1","Cell RNA - ASC diff [nTPM]":"392.1","Cell RNA - ASC TERT1 [nTPM]":"370.1","Cell RNA - BEWO [nTPM]":"31.2","Cell RNA - BJ [nTPM]":"804.0","Cell RNA - BJ hTERT+ [nTPM]":"741.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"336.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"350.1","Cell RNA - CACO-2 [nTPM]":"113.1","Cell RNA - CAPAN-2 [nTPM]":"594.2","Cell RNA - Daudi [nTPM]":"35.3","Cell RNA - EFO-21 [nTPM]":"54.3","Cell RNA - fHDF\/TERT166 [nTPM]":"474.6","Cell RNA - GAMG [nTPM]":"270.3","Cell RNA - HaCaT [nTPM]":"167.5","Cell RNA - HAP1 [nTPM]":"56.2","Cell RNA - HBEC3-KT [nTPM]":"281.1","Cell RNA - HBF TERT88 [nTPM]":"570.0","Cell RNA - HDLM-2 [nTPM]":"13.6","Cell RNA - HEK 293 [nTPM]":"57.0","Cell RNA - HEL [nTPM]":"81.1","Cell RNA - HeLa [nTPM]":"372.5","Cell RNA - Hep G2 [nTPM]":"310.3","Cell RNA - HHSteC [nTPM]":"251.2","Cell RNA - HL-60 [nTPM]":"12.5","Cell RNA - HMC-1 [nTPM]":"12.9","Cell RNA - HSkMC [nTPM]":"306.5","Cell RNA - hTCEpi [nTPM]":"61.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"187.6","Cell RNA - hTERT-HME1 [nTPM]":"237.4","Cell RNA - hTERT-RPE1 [nTPM]":"657.2","Cell RNA - HUVEC TERT2 [nTPM]":"144.8","Cell RNA - JURKAT [nTPM]":"18.0","Cell RNA - K-562 [nTPM]":"22.2","Cell RNA - Karpas-707 [nTPM]":"32.1","Cell RNA - LHCN-M2 [nTPM]":"300.2","Cell RNA - MCF7 [nTPM]":"97.4","Cell RNA - MOLT-4 [nTPM]":"3.3","Cell RNA - NB-4 [nTPM]":"16.6","Cell RNA - NTERA-2 [nTPM]":"51.7","Cell RNA - OE19 [nTPM]":"441.6","Cell RNA - PC-3 [nTPM]":"383.4","Cell RNA - REH [nTPM]":"22.3","Cell RNA - RH-30 [nTPM]":"97.0","Cell RNA - RPMI-8226 [nTPM]":"7.3","Cell RNA - RPTEC TERT1 [nTPM]":"206.2","Cell RNA - RT4 [nTPM]":"374.0","Cell RNA - SCLC-21H [nTPM]":"93.1","Cell RNA - SH-SY5Y [nTPM]":"32.1","Cell RNA - SiHa [nTPM]":"249.9","Cell RNA - SK-BR-3 [nTPM]":"116.1","Cell RNA - SK-MEL-30 [nTPM]":"101.7","Cell RNA - SuSa [nTPM]":"49.0","Cell RNA - T-47d [nTPM]":"47.7","Cell RNA - THP-1 [nTPM]":"22.2","Cell RNA - TIME [nTPM]":"456.7","Cell RNA - U-138 MG [nTPM]":"338.0","Cell RNA - U-2 OS [nTPM]":"174.3","Cell RNA - U-2197 [nTPM]":"313.0","Cell RNA - U-251 MG [nTPM]":"288.0","Cell RNA - U-266\/70 [nTPM]":"20.2","Cell RNA - U-266\/84 [nTPM]":"27.1","Cell RNA - U-698 [nTPM]":"1.5","Cell RNA - U-87 MG [nTPM]":"890.1","Cell RNA - U-937 [nTPM]":"7.5","Cell RNA - WM-115 [nTPM]":"231.4","Blood RNA - basophil [nTPM]":"1.9","Blood RNA - classical monocyte [nTPM]":"8.3","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"2.5","Blood RNA - intermediate monocyte [nTPM]":"2.9","Blood RNA - MAIT T-cell [nTPM]":"4.7","Blood RNA - memory B-cell [nTPM]":"5.5","Blood RNA - memory CD4 T-cell [nTPM]":"3.5","Blood RNA - memory CD8 T-cell [nTPM]":"2.4","Blood RNA - myeloid DC [nTPM]":"10.0","Blood RNA - naive B-cell [nTPM]":"5.0","Blood RNA - naive CD4 T-cell [nTPM]":"4.9","Blood RNA - naive CD8 T-cell [nTPM]":"2.5","Blood RNA - neutrophil [nTPM]":"25.4","Blood RNA - NK-cell [nTPM]":"8.7","Blood RNA - non-classical monocyte [nTPM]":"1.8","Blood RNA - plasmacytoid DC [nTPM]":"34.0","Blood RNA - T-reg [nTPM]":"4.0","Blood RNA - total PBMC [nTPM]":"4.1","Brain RNA - amygdala [nTPM]":"64.7","Brain RNA - basal ganglia [nTPM]":"69.2","Brain RNA - cerebellum [nTPM]":"102.3","Brain RNA - cerebral cortex [nTPM]":"88.9","Brain RNA - hippocampal formation [nTPM]":"64.5","Brain RNA - hypothalamus [nTPM]":"58.4","Brain RNA - medulla oblongata [nTPM]":"54.0","Brain RNA - midbrain [nTPM]":"69.2","Brain RNA - pons [nTPM]":"52.2","Brain RNA - spinal cord [nTPM]":"44.8","Brain RNA - thalamus [nTPM]":"71.8","Brain RNA - white matter [nTPM]":"60.4","Single Cell Type RNA - Adipocytes [nTPM]":"79.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"195.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"244.0","Single Cell Type RNA - Astrocytes [nTPM]":"366.6","Single Cell Type RNA - B-cells [nTPM]":"13.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"47.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"160.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"126.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"68.9","Single Cell Type RNA - Bipolar cells [nTPM]":"138.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"83.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"58.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"228.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"37.1","Single Cell Type RNA - Club cells [nTPM]":"157.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"86.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"294.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"118.1","Single Cell Type RNA - dendritic cells [nTPM]":"40.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"57.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"144.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"51.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"65.8","Single Cell Type RNA - Endothelial cells [nTPM]":"85.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"116.5","Single Cell Type RNA - Erythroid cells [nTPM]":"13.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"93.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"180.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"107.1","Single Cell Type RNA - Fibroblasts [nTPM]":"132.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"73.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"115.4","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"34.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"42.8","Single Cell Type RNA - Hepatocytes [nTPM]":"62.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"72.2","Single Cell Type RNA - Horizontal cells [nTPM]":"127.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"98.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"215.1","Single Cell Type RNA - Ionocytes [nTPM]":"52.9","Single Cell Type RNA - Kupffer cells [nTPM]":"26.6","Single Cell Type RNA - Langerhans cells [nTPM]":"44.1","Single Cell Type RNA - Late spermatids [nTPM]":"3.1","Single Cell Type RNA - Leydig cells [nTPM]":"70.8","Single Cell Type RNA - Macrophages [nTPM]":"48.1","Single Cell Type RNA - Melanocytes [nTPM]":"42.7","Single Cell Type RNA - Microglial cells [nTPM]":"61.8","Single Cell Type RNA - monocytes [nTPM]":"20.0","Single Cell Type RNA - Muller glia cells [nTPM]":"468.8","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"154.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"53.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"257.7","Single Cell Type RNA - Paneth cells [nTPM]":"32.3","Single Cell Type RNA - Peritubular cells [nTPM]":"57.6","Single Cell Type RNA - Plasma cells [nTPM]":"15.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"148.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"34.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"34.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"66.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"158.8","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"114.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"92.7","Single Cell Type RNA - Spermatocytes [nTPM]":"3.4","Single Cell Type RNA - Spermatogonia [nTPM]":"16.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"101.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"50.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"48.0","Single Cell Type RNA - T-cells [nTPM]":"13.6","Single Cell Type RNA - Theca cells [nTPM]":"131.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"67.3","Single Cell Type RNA - Urothelial cells [nTPM]":"254.2"},{"Gene":"ASS1","Gene synonym":["ASS","CTLN1"],"Ensembl":"ENSG00000130707","Gene description":"Argininosuccinate synthase 1","Uniprot":["P00966"],"Chromosome":"9","Position":"130444961-130501274","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Amino-acid biosynthesis","Arginine biosynthesis","Urea cycle"],"Molecular function":["Ligase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"kidney":"1284.8","liver":"2037.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"398.7","Hepatocytes":"1062.0","Proximal enterocytes":"618.2","Proximal tubular cells":"1408.9","Urothelial cells":"413.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"15","RNA blood cell specific nTPM":{"plasmacytoid DC":"1.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"15","RNA blood lineage specific nTPM":{"dendritic cells":"1.5"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+":"893.9","HaCaT":"850.4","hTCEpi":"817.8","RPMI-8226":"1444.5","THP-1":"1061.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020896","HPA020934"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6400000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA020896":"AB_1845117","HPA020934":"AB_1845118"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.14e-9"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-3"},"Tissue RNA - adipose tissue [nTPM]":"215.0","Tissue RNA - adrenal gland [nTPM]":"146.8","Tissue RNA - amygdala [nTPM]":"29.6","Tissue RNA - appendix [nTPM]":"51.3","Tissue RNA - basal ganglia [nTPM]":"29.7","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"168.2","Tissue RNA - cerebellum [nTPM]":"25.0","Tissue RNA - cerebral cortex [nTPM]":"31.0","Tissue RNA - cervix [nTPM]":"67.0","Tissue RNA - choroid plexus [nTPM]":"61.7","Tissue RNA - colon [nTPM]":"157.2","Tissue RNA - duodenum [nTPM]":"124.5","Tissue RNA - endometrium 1 [nTPM]":"111.3","Tissue RNA - epididymis [nTPM]":"124.8","Tissue RNA - esophagus [nTPM]":"51.1","Tissue RNA - fallopian tube [nTPM]":"166.3","Tissue RNA - gallbladder [nTPM]":"110.2","Tissue RNA - heart muscle [nTPM]":"66.5","Tissue RNA - hippocampal formation [nTPM]":"31.5","Tissue RNA - hypothalamus [nTPM]":"38.3","Tissue RNA - kidney [nTPM]":"1284.8","Tissue RNA - liver [nTPM]":"2037.7","Tissue RNA - lung [nTPM]":"52.9","Tissue RNA - lymph node [nTPM]":"7.5","Tissue RNA - medulla oblongata [nTPM]":"40.2","Tissue RNA - midbrain [nTPM]":"42.2","Tissue RNA - ovary [nTPM]":"57.2","Tissue RNA - pancreas [nTPM]":"68.4","Tissue RNA - parathyroid gland [nTPM]":"11.4","Tissue RNA - pituitary gland [nTPM]":"45.0","Tissue RNA - placenta [nTPM]":"50.6","Tissue RNA - pons [nTPM]":"51.7","Tissue RNA - prostate [nTPM]":"56.2","Tissue RNA - rectum [nTPM]":"167.9","Tissue RNA - retina [nTPM]":"6.9","Tissue RNA - salivary gland [nTPM]":"119.4","Tissue RNA - seminal vesicle [nTPM]":"132.6","Tissue RNA - skeletal muscle [nTPM]":"74.4","Tissue RNA - skin 1 [nTPM]":"131.3","Tissue RNA - small intestine [nTPM]":"194.8","Tissue RNA - smooth muscle [nTPM]":"61.2","Tissue RNA - spinal cord [nTPM]":"28.4","Tissue RNA - spleen [nTPM]":"20.0","Tissue RNA - stomach 1 [nTPM]":"53.2","Tissue RNA - testis [nTPM]":"35.9","Tissue RNA - thalamus [nTPM]":"38.4","Tissue RNA - thymus [nTPM]":"7.8","Tissue RNA - thyroid gland [nTPM]":"92.3","Tissue RNA - tongue [nTPM]":"71.4","Tissue RNA - tonsil [nTPM]":"15.6","Tissue RNA - urinary bladder [nTPM]":"288.7","Tissue RNA - vagina [nTPM]":"66.6","Tissue RNA - white matter [nTPM]":"25.3","Cell RNA - A-431 [nTPM]":"124.5","Cell RNA - A549 [nTPM]":"11.9","Cell RNA - AF22 [nTPM]":"13.7","Cell RNA - AN3-CA [nTPM]":"23.1","Cell RNA - ASC diff [nTPM]":"88.4","Cell RNA - ASC TERT1 [nTPM]":"223.1","Cell RNA - BEWO [nTPM]":"43.6","Cell RNA - BJ [nTPM]":"146.2","Cell RNA - BJ hTERT+ [nTPM]":"893.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"28.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"85.5","Cell RNA - CACO-2 [nTPM]":"52.5","Cell RNA - CAPAN-2 [nTPM]":"34.0","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"95.9","Cell RNA - fHDF\/TERT166 [nTPM]":"300.2","Cell RNA - GAMG [nTPM]":"8.2","Cell RNA - HaCaT [nTPM]":"850.4","Cell RNA - HAP1 [nTPM]":"59.9","Cell RNA - HBEC3-KT [nTPM]":"5.2","Cell RNA - HBF TERT88 [nTPM]":"19.5","Cell RNA - HDLM-2 [nTPM]":"21.7","Cell RNA - HEK 293 [nTPM]":"27.1","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"18.3","Cell RNA - Hep G2 [nTPM]":"137.3","Cell RNA - HHSteC [nTPM]":"305.4","Cell RNA - HL-60 [nTPM]":"18.3","Cell RNA - HMC-1 [nTPM]":"1.6","Cell RNA - HSkMC [nTPM]":"148.2","Cell RNA - hTCEpi [nTPM]":"817.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"45.4","Cell RNA - hTERT-HME1 [nTPM]":"81.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"1.1","Cell RNA - JURKAT [nTPM]":"384.0","Cell RNA - K-562 [nTPM]":"5.3","Cell RNA - Karpas-707 [nTPM]":"530.6","Cell RNA - LHCN-M2 [nTPM]":"28.8","Cell RNA - MCF7 [nTPM]":"619.8","Cell RNA - MOLT-4 [nTPM]":"7.2","Cell RNA - NB-4 [nTPM]":"262.7","Cell RNA - NTERA-2 [nTPM]":"19.2","Cell RNA - OE19 [nTPM]":"635.9","Cell RNA - PC-3 [nTPM]":"26.7","Cell RNA - REH [nTPM]":"1.7","Cell RNA - RH-30 [nTPM]":"15.4","Cell RNA - RPMI-8226 [nTPM]":"1444.5","Cell RNA - RPTEC TERT1 [nTPM]":"78.8","Cell RNA - RT4 [nTPM]":"61.3","Cell RNA - SCLC-21H [nTPM]":"342.4","Cell RNA - SH-SY5Y [nTPM]":"5.8","Cell RNA - SiHa [nTPM]":"515.4","Cell RNA - SK-BR-3 [nTPM]":"534.7","Cell RNA - SK-MEL-30 [nTPM]":"41.5","Cell RNA - SuSa [nTPM]":"53.5","Cell RNA - T-47d [nTPM]":"366.1","Cell RNA - THP-1 [nTPM]":"1061.5","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"11.3","Cell RNA - U-2 OS [nTPM]":"68.3","Cell RNA - U-2197 [nTPM]":"2.3","Cell RNA - U-251 MG [nTPM]":"13.0","Cell RNA - U-266\/70 [nTPM]":"88.1","Cell RNA - U-266\/84 [nTPM]":"91.5","Cell RNA - U-698 [nTPM]":"32.1","Cell RNA - U-87 MG [nTPM]":"219.0","Cell RNA - U-937 [nTPM]":"137.0","Cell RNA - WM-115 [nTPM]":"1.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"29.6","Brain RNA - basal ganglia [nTPM]":"29.7","Brain RNA - cerebellum [nTPM]":"25.0","Brain RNA - cerebral cortex [nTPM]":"31.0","Brain RNA - hippocampal formation [nTPM]":"31.5","Brain RNA - hypothalamus [nTPM]":"38.3","Brain RNA - medulla oblongata [nTPM]":"40.2","Brain RNA - midbrain [nTPM]":"42.2","Brain RNA - pons [nTPM]":"51.7","Brain RNA - spinal cord [nTPM]":"28.4","Brain RNA - thalamus [nTPM]":"38.4","Brain RNA - white matter [nTPM]":"25.3","Single Cell Type RNA - Adipocytes [nTPM]":"72.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"28.6","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"21.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"70.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"55.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"179.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"53.5","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"138.7","Single Cell Type RNA - Club cells [nTPM]":"104.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"47.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"178.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"398.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"133.1","Single Cell Type RNA - Ductal cells [nTPM]":"116.5","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"30.5","Single Cell Type RNA - Endothelial cells [nTPM]":"68.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.0","Single Cell Type RNA - Erythroid cells [nTPM]":"93.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"110.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.9","Single Cell Type RNA - Fibroblasts [nTPM]":"21.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.2","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"55.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"65.7","Single Cell Type RNA - Hepatocytes [nTPM]":"1062.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"186.8","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"40.1","Single Cell Type RNA - Langerhans cells [nTPM]":"6.5","Single Cell Type RNA - Late spermatids [nTPM]":"7.8","Single Cell Type RNA - Leydig cells [nTPM]":"31.1","Single Cell Type RNA - Macrophages [nTPM]":"8.0","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"1.6","Single Cell Type RNA - Muller glia cells [nTPM]":"10.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"70.8","Single Cell Type RNA - Paneth cells [nTPM]":"310.4","Single Cell Type RNA - Peritubular cells [nTPM]":"124.8","Single Cell Type RNA - Plasma cells [nTPM]":"11.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"104.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"618.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1408.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"32.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.4","Single Cell Type RNA - Spermatocytes [nTPM]":"1.4","Single Cell Type RNA - Spermatogonia [nTPM]":"2.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"144.1","Single Cell Type RNA - T-cells [nTPM]":"11.5","Single Cell Type RNA - Theca cells [nTPM]":"62.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"165.6","Single Cell Type RNA - Urothelial cells [nTPM]":"413.2"},{"Gene":"ATG16L1","Gene synonym":["APG16L","ATG16A","ATG16L","FLJ10035","WDR30"],"Ensembl":"ENSG00000085978","Gene description":"Autophagy related 16 like 1","Uniprot":["Q676U5"],"Chromosome":"2","Position":"233210051-233295674","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Autophagy","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012577","HPA063900"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA012577":"AB_1845155","HPA063900":"AB_2685146"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.48e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.70e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.6","Tissue RNA - adrenal gland [nTPM]":"7.8","Tissue RNA - amygdala [nTPM]":"7.0","Tissue RNA - appendix [nTPM]":"3.8","Tissue RNA - basal ganglia [nTPM]":"7.5","Tissue RNA - bone marrow [nTPM]":"14.3","Tissue RNA - breast [nTPM]":"8.8","Tissue RNA - cerebellum [nTPM]":"7.9","Tissue RNA - cerebral cortex [nTPM]":"8.4","Tissue RNA - cervix [nTPM]":"8.1","Tissue RNA - choroid plexus [nTPM]":"12.8","Tissue RNA - colon [nTPM]":"11.1","Tissue RNA - duodenum [nTPM]":"5.0","Tissue RNA - endometrium 1 [nTPM]":"9.6","Tissue RNA - epididymis [nTPM]":"5.5","Tissue RNA - esophagus [nTPM]":"11.6","Tissue RNA - fallopian tube [nTPM]":"7.1","Tissue RNA - gallbladder [nTPM]":"3.3","Tissue RNA - heart muscle [nTPM]":"10.7","Tissue RNA - hippocampal formation [nTPM]":"7.3","Tissue RNA - hypothalamus [nTPM]":"6.6","Tissue RNA - kidney [nTPM]":"9.2","Tissue RNA - liver [nTPM]":"15.1","Tissue RNA - lung [nTPM]":"7.6","Tissue RNA - lymph node [nTPM]":"5.8","Tissue RNA - medulla oblongata [nTPM]":"6.5","Tissue RNA - midbrain [nTPM]":"6.3","Tissue RNA - ovary [nTPM]":"8.5","Tissue RNA - pancreas [nTPM]":"8.6","Tissue RNA - parathyroid gland [nTPM]":"5.3","Tissue RNA - pituitary gland [nTPM]":"5.5","Tissue RNA - placenta [nTPM]":"4.0","Tissue RNA - pons [nTPM]":"6.9","Tissue RNA - prostate [nTPM]":"12.1","Tissue RNA - rectum [nTPM]":"5.2","Tissue RNA - retina [nTPM]":"5.6","Tissue RNA - salivary gland [nTPM]":"11.5","Tissue RNA - seminal vesicle [nTPM]":"4.3","Tissue RNA - skeletal muscle [nTPM]":"19.9","Tissue RNA - skin 1 [nTPM]":"17.2","Tissue RNA - small intestine [nTPM]":"11.1","Tissue RNA - smooth muscle [nTPM]":"5.2","Tissue RNA - spinal cord [nTPM]":"6.3","Tissue RNA - spleen [nTPM]":"11.5","Tissue RNA - stomach 1 [nTPM]":"11.1","Tissue RNA - testis [nTPM]":"13.5","Tissue RNA - thalamus [nTPM]":"6.5","Tissue RNA - thymus [nTPM]":"5.9","Tissue RNA - thyroid gland [nTPM]":"11.2","Tissue RNA - tongue [nTPM]":"6.1","Tissue RNA - tonsil [nTPM]":"5.2","Tissue RNA - urinary bladder [nTPM]":"11.5","Tissue RNA - vagina [nTPM]":"8.2","Tissue RNA - white matter [nTPM]":"7.7","Cell RNA - A-431 [nTPM]":"13.3","Cell RNA - A549 [nTPM]":"12.2","Cell RNA - AF22 [nTPM]":"4.9","Cell RNA - AN3-CA [nTPM]":"8.5","Cell RNA - ASC diff [nTPM]":"12.4","Cell RNA - ASC TERT1 [nTPM]":"8.0","Cell RNA - BEWO [nTPM]":"14.0","Cell RNA - BJ [nTPM]":"11.4","Cell RNA - BJ hTERT+ [nTPM]":"9.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.9","Cell RNA - CACO-2 [nTPM]":"8.9","Cell RNA - CAPAN-2 [nTPM]":"9.7","Cell RNA - Daudi [nTPM]":"3.1","Cell RNA - EFO-21 [nTPM]":"3.7","Cell RNA - fHDF\/TERT166 [nTPM]":"8.9","Cell RNA - GAMG [nTPM]":"14.3","Cell RNA - HaCaT [nTPM]":"7.7","Cell RNA - HAP1 [nTPM]":"9.8","Cell RNA - HBEC3-KT [nTPM]":"6.4","Cell RNA - HBF TERT88 [nTPM]":"9.8","Cell RNA - HDLM-2 [nTPM]":"6.2","Cell RNA - HEK 293 [nTPM]":"7.7","Cell RNA - HEL [nTPM]":"7.1","Cell RNA - HeLa [nTPM]":"9.1","Cell RNA - Hep G2 [nTPM]":"14.6","Cell RNA - HHSteC [nTPM]":"9.1","Cell RNA - HL-60 [nTPM]":"5.6","Cell RNA - HMC-1 [nTPM]":"9.0","Cell RNA - HSkMC [nTPM]":"5.3","Cell RNA - hTCEpi [nTPM]":"9.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.5","Cell RNA - hTERT-HME1 [nTPM]":"8.7","Cell RNA - hTERT-RPE1 [nTPM]":"7.2","Cell RNA - HUVEC TERT2 [nTPM]":"9.0","Cell RNA - JURKAT [nTPM]":"4.7","Cell RNA - K-562 [nTPM]":"7.6","Cell RNA - Karpas-707 [nTPM]":"2.9","Cell RNA - LHCN-M2 [nTPM]":"10.2","Cell RNA - MCF7 [nTPM]":"9.3","Cell RNA - MOLT-4 [nTPM]":"6.7","Cell RNA - NB-4 [nTPM]":"11.2","Cell RNA - NTERA-2 [nTPM]":"19.1","Cell RNA - OE19 [nTPM]":"14.1","Cell RNA - PC-3 [nTPM]":"17.6","Cell RNA - REH [nTPM]":"4.8","Cell RNA - RH-30 [nTPM]":"10.3","Cell RNA - RPMI-8226 [nTPM]":"2.6","Cell RNA - RPTEC TERT1 [nTPM]":"9.9","Cell RNA - RT4 [nTPM]":"8.4","Cell RNA - SCLC-21H [nTPM]":"8.8","Cell RNA - SH-SY5Y [nTPM]":"6.5","Cell RNA - SiHa [nTPM]":"7.8","Cell RNA - SK-BR-3 [nTPM]":"8.5","Cell RNA - SK-MEL-30 [nTPM]":"8.5","Cell RNA - SuSa [nTPM]":"7.4","Cell RNA - T-47d [nTPM]":"5.3","Cell RNA - THP-1 [nTPM]":"7.1","Cell RNA - TIME [nTPM]":"10.7","Cell RNA - U-138 MG [nTPM]":"6.2","Cell RNA - U-2 OS [nTPM]":"5.4","Cell RNA - U-2197 [nTPM]":"9.6","Cell RNA - U-251 MG [nTPM]":"10.3","Cell RNA - U-266\/70 [nTPM]":"6.5","Cell RNA - U-266\/84 [nTPM]":"3.9","Cell RNA - U-698 [nTPM]":"6.1","Cell RNA - U-87 MG [nTPM]":"10.5","Cell RNA - U-937 [nTPM]":"5.7","Cell RNA - WM-115 [nTPM]":"10.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.7","Blood RNA - eosinophil [nTPM]":"2.9","Blood RNA - gdT-cell [nTPM]":"4.8","Blood RNA - intermediate monocyte [nTPM]":"1.4","Blood RNA - MAIT T-cell [nTPM]":"3.7","Blood RNA - memory B-cell [nTPM]":"2.0","Blood RNA - memory CD4 T-cell [nTPM]":"3.1","Blood RNA - memory CD8 T-cell [nTPM]":"4.4","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"2.2","Blood RNA - naive CD4 T-cell [nTPM]":"3.5","Blood RNA - naive CD8 T-cell [nTPM]":"3.5","Blood RNA - neutrophil [nTPM]":"1.2","Blood RNA - NK-cell [nTPM]":"4.1","Blood RNA - non-classical monocyte [nTPM]":"4.7","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"3.8","Blood RNA - total PBMC [nTPM]":"2.1","Brain RNA - amygdala [nTPM]":"7.0","Brain RNA - basal ganglia [nTPM]":"7.5","Brain RNA - cerebellum [nTPM]":"7.9","Brain RNA - cerebral cortex [nTPM]":"8.4","Brain RNA - hippocampal formation [nTPM]":"7.3","Brain RNA - hypothalamus [nTPM]":"6.6","Brain RNA - medulla oblongata [nTPM]":"6.5","Brain RNA - midbrain [nTPM]":"6.3","Brain RNA - pons [nTPM]":"6.9","Brain RNA - spinal cord [nTPM]":"6.3","Brain RNA - thalamus [nTPM]":"6.5","Brain RNA - white matter [nTPM]":"7.7","Single Cell Type RNA - Adipocytes [nTPM]":"6.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.2","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"7.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"8.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"11.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.6","Single Cell Type RNA - dendritic cells [nTPM]":"20.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.9","Single Cell Type RNA - Endothelial cells [nTPM]":"6.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.0","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"31.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.2","Single Cell Type RNA - Fibroblasts [nTPM]":"5.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"31.8","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"6.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"10.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.6","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.1","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"6.3","Single Cell Type RNA - Langerhans cells [nTPM]":"5.7","Single Cell Type RNA - Late spermatids [nTPM]":"1.7","Single Cell Type RNA - Leydig cells [nTPM]":"4.1","Single Cell Type RNA - Macrophages [nTPM]":"5.1","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"6.6","Single Cell Type RNA - Muller glia cells [nTPM]":"7.1","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.8","Single Cell Type RNA - Paneth cells [nTPM]":"8.0","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"8.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.9","Single Cell Type RNA - Spermatocytes [nTPM]":"11.0","Single Cell Type RNA - Spermatogonia [nTPM]":"17.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.7","Single Cell Type RNA - T-cells [nTPM]":"19.2","Single Cell Type RNA - Theca cells [nTPM]":"5.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.4","Single Cell Type RNA - Urothelial cells [nTPM]":"6.0"},{"Gene":"ATG5","Gene synonym":["APG5","APG5L","ASP","hAPG5"],"Ensembl":"ENSG00000057663","Gene description":"Autophagy related 5","Uniprot":["Q9H1Y0"],"Chromosome":"6","Position":"106045423-106325791","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Apoptosis","Autophagy","Host-virus interaction","Immunity"],"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034432","CAB037309","HPA042973"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"CAB034432":"AB_2243288","CAB037309":"AB_796188","HPA042973":"AB_2678246"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.84e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.73e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Tissue RNA - adipose tissue [nTPM]":"12.5","Tissue RNA - adrenal gland [nTPM]":"19.2","Tissue RNA - amygdala [nTPM]":"9.9","Tissue RNA - appendix [nTPM]":"6.7","Tissue RNA - basal ganglia [nTPM]":"10.2","Tissue RNA - bone marrow [nTPM]":"8.1","Tissue RNA - breast [nTPM]":"15.4","Tissue RNA - cerebellum [nTPM]":"10.5","Tissue RNA - cerebral cortex [nTPM]":"13.2","Tissue RNA - cervix [nTPM]":"15.3","Tissue RNA - choroid plexus [nTPM]":"10.7","Tissue RNA - colon [nTPM]":"15.8","Tissue RNA - duodenum [nTPM]":"12.8","Tissue RNA - endometrium 1 [nTPM]":"14.9","Tissue RNA - epididymis [nTPM]":"16.6","Tissue RNA - esophagus [nTPM]":"12.3","Tissue RNA - fallopian tube [nTPM]":"14.7","Tissue RNA - gallbladder [nTPM]":"9.5","Tissue RNA - heart muscle [nTPM]":"9.7","Tissue RNA - hippocampal formation [nTPM]":"10.3","Tissue RNA - hypothalamus [nTPM]":"10.7","Tissue RNA - kidney [nTPM]":"14.4","Tissue RNA - liver [nTPM]":"17.7","Tissue RNA - lung [nTPM]":"10.8","Tissue RNA - lymph node [nTPM]":"8.5","Tissue RNA - medulla oblongata [nTPM]":"10.0","Tissue RNA - midbrain [nTPM]":"10.3","Tissue RNA - ovary [nTPM]":"14.3","Tissue RNA - pancreas [nTPM]":"12.1","Tissue RNA - parathyroid gland [nTPM]":"11.8","Tissue RNA - pituitary gland [nTPM]":"7.9","Tissue RNA - placenta [nTPM]":"13.2","Tissue RNA - pons [nTPM]":"9.9","Tissue RNA - prostate [nTPM]":"15.3","Tissue RNA - rectum [nTPM]":"15.2","Tissue RNA - retina [nTPM]":"10.5","Tissue RNA - salivary gland [nTPM]":"11.8","Tissue RNA - seminal vesicle [nTPM]":"13.1","Tissue RNA - skeletal muscle [nTPM]":"15.7","Tissue RNA - skin 1 [nTPM]":"8.0","Tissue RNA - small intestine [nTPM]":"13.1","Tissue RNA - smooth muscle [nTPM]":"14.2","Tissue RNA - spinal cord [nTPM]":"9.5","Tissue RNA - spleen [nTPM]":"10.6","Tissue RNA - stomach 1 [nTPM]":"12.0","Tissue RNA - testis [nTPM]":"8.3","Tissue RNA - thalamus [nTPM]":"10.2","Tissue RNA - thymus [nTPM]":"9.4","Tissue RNA - thyroid gland [nTPM]":"17.5","Tissue RNA - tongue [nTPM]":"15.2","Tissue RNA - tonsil [nTPM]":"9.8","Tissue RNA - urinary bladder [nTPM]":"13.4","Tissue RNA - vagina [nTPM]":"11.9","Tissue RNA - white matter [nTPM]":"10.5","Cell RNA - A-431 [nTPM]":"14.6","Cell RNA - A549 [nTPM]":"6.0","Cell RNA - AF22 [nTPM]":"10.3","Cell RNA - AN3-CA [nTPM]":"14.0","Cell RNA - ASC diff [nTPM]":"23.2","Cell RNA - ASC TERT1 [nTPM]":"24.0","Cell RNA - BEWO [nTPM]":"10.7","Cell RNA - BJ [nTPM]":"15.4","Cell RNA - BJ hTERT+ [nTPM]":"24.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"22.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"27.2","Cell RNA - CACO-2 [nTPM]":"6.2","Cell RNA - CAPAN-2 [nTPM]":"8.6","Cell RNA - Daudi [nTPM]":"10.2","Cell RNA - EFO-21 [nTPM]":"12.0","Cell RNA - fHDF\/TERT166 [nTPM]":"23.7","Cell RNA - GAMG [nTPM]":"25.0","Cell RNA - HaCaT [nTPM]":"10.2","Cell RNA - HAP1 [nTPM]":"15.2","Cell RNA - HBEC3-KT [nTPM]":"22.2","Cell RNA - HBF TERT88 [nTPM]":"39.2","Cell RNA - HDLM-2 [nTPM]":"4.6","Cell RNA - HEK 293 [nTPM]":"7.3","Cell RNA - HEL [nTPM]":"11.8","Cell RNA - HeLa [nTPM]":"6.8","Cell RNA - Hep G2 [nTPM]":"7.8","Cell RNA - HHSteC [nTPM]":"25.0","Cell RNA - HL-60 [nTPM]":"14.6","Cell RNA - HMC-1 [nTPM]":"6.0","Cell RNA - HSkMC [nTPM]":"19.3","Cell RNA - hTCEpi [nTPM]":"24.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.1","Cell RNA - hTERT-HME1 [nTPM]":"20.0","Cell RNA - hTERT-RPE1 [nTPM]":"29.7","Cell RNA - HUVEC TERT2 [nTPM]":"23.9","Cell RNA - JURKAT [nTPM]":"9.4","Cell RNA - K-562 [nTPM]":"17.6","Cell RNA - Karpas-707 [nTPM]":"10.0","Cell RNA - LHCN-M2 [nTPM]":"25.7","Cell RNA - MCF7 [nTPM]":"6.4","Cell RNA - MOLT-4 [nTPM]":"6.0","Cell RNA - NB-4 [nTPM]":"17.5","Cell RNA - NTERA-2 [nTPM]":"11.9","Cell RNA - OE19 [nTPM]":"19.4","Cell RNA - PC-3 [nTPM]":"8.3","Cell RNA - REH [nTPM]":"6.0","Cell RNA - RH-30 [nTPM]":"23.7","Cell RNA - RPMI-8226 [nTPM]":"7.9","Cell RNA - RPTEC TERT1 [nTPM]":"24.0","Cell RNA - RT4 [nTPM]":"10.3","Cell RNA - SCLC-21H [nTPM]":"7.1","Cell RNA - SH-SY5Y [nTPM]":"6.9","Cell RNA - SiHa [nTPM]":"9.4","Cell RNA - SK-BR-3 [nTPM]":"17.8","Cell RNA - SK-MEL-30 [nTPM]":"14.6","Cell RNA - SuSa [nTPM]":"18.6","Cell RNA - T-47d [nTPM]":"8.5","Cell RNA - THP-1 [nTPM]":"27.5","Cell RNA - TIME [nTPM]":"19.8","Cell RNA - U-138 MG [nTPM]":"8.6","Cell RNA - U-2 OS [nTPM]":"4.8","Cell RNA - U-2197 [nTPM]":"10.1","Cell RNA - U-251 MG [nTPM]":"26.7","Cell RNA - U-266\/70 [nTPM]":"4.1","Cell RNA - U-266\/84 [nTPM]":"4.2","Cell RNA - U-698 [nTPM]":"9.3","Cell RNA - U-87 MG [nTPM]":"31.7","Cell RNA - U-937 [nTPM]":"19.6","Cell RNA - WM-115 [nTPM]":"16.1","Blood RNA - basophil [nTPM]":"4.7","Blood RNA - classical monocyte [nTPM]":"4.8","Blood RNA - eosinophil [nTPM]":"9.6","Blood RNA - gdT-cell [nTPM]":"2.9","Blood RNA - intermediate monocyte [nTPM]":"6.1","Blood RNA - MAIT T-cell [nTPM]":"8.4","Blood RNA - memory B-cell [nTPM]":"5.1","Blood RNA - memory CD4 T-cell [nTPM]":"5.6","Blood RNA - memory CD8 T-cell [nTPM]":"4.6","Blood RNA - myeloid DC [nTPM]":"5.3","Blood RNA - naive B-cell [nTPM]":"3.3","Blood RNA - naive CD4 T-cell [nTPM]":"6.0","Blood RNA - naive CD8 T-cell [nTPM]":"5.0","Blood RNA - neutrophil [nTPM]":"4.1","Blood RNA - NK-cell [nTPM]":"4.8","Blood RNA - non-classical monocyte [nTPM]":"8.8","Blood RNA - plasmacytoid DC [nTPM]":"1.9","Blood RNA - T-reg [nTPM]":"6.9","Blood RNA - total PBMC [nTPM]":"3.3","Brain RNA - amygdala [nTPM]":"9.9","Brain RNA - basal ganglia [nTPM]":"10.2","Brain RNA - cerebellum [nTPM]":"10.5","Brain RNA - cerebral cortex [nTPM]":"13.2","Brain RNA - hippocampal formation [nTPM]":"10.3","Brain RNA - hypothalamus [nTPM]":"10.7","Brain RNA - medulla oblongata [nTPM]":"10.0","Brain RNA - midbrain [nTPM]":"10.3","Brain RNA - pons [nTPM]":"9.9","Brain RNA - spinal cord [nTPM]":"9.5","Brain RNA - thalamus [nTPM]":"10.2","Brain RNA - white matter [nTPM]":"10.5","Single Cell Type RNA - Adipocytes [nTPM]":"35.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.9","Single Cell Type RNA - Astrocytes [nTPM]":"24.2","Single Cell Type RNA - B-cells [nTPM]":"41.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"26.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"28.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"45.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.6","Single Cell Type RNA - Bipolar cells [nTPM]":"14.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"26.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"36.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"47.3","Single Cell Type RNA - dendritic cells [nTPM]":"46.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"48.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"29.4","Single Cell Type RNA - Ductal cells [nTPM]":"39.6","Single Cell Type RNA - Early spermatids [nTPM]":"35.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"33.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"27.4","Single Cell Type RNA - Endothelial cells [nTPM]":"25.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.2","Single Cell Type RNA - Erythroid cells [nTPM]":"27.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"79.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"44.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"63.8","Single Cell Type RNA - Fibroblasts [nTPM]":"25.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"42.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"34.5","Single Cell Type RNA - granulocytes [nTPM]":"20.3","Single Cell Type RNA - Granulosa cells [nTPM]":"20.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.8","Single Cell Type RNA - Hepatocytes [nTPM]":"20.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"38.1","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"71.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"38.4","Single Cell Type RNA - Ionocytes [nTPM]":"36.7","Single Cell Type RNA - Kupffer cells [nTPM]":"26.9","Single Cell Type RNA - Langerhans cells [nTPM]":"32.3","Single Cell Type RNA - Late spermatids [nTPM]":"13.7","Single Cell Type RNA - Leydig cells [nTPM]":"20.5","Single Cell Type RNA - Macrophages [nTPM]":"33.6","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"43.1","Single Cell Type RNA - monocytes [nTPM]":"44.6","Single Cell Type RNA - Muller glia cells [nTPM]":"18.3","Single Cell Type RNA - NK-cells [nTPM]":"44.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"43.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"49.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"40.5","Single Cell Type RNA - Paneth cells [nTPM]":"59.8","Single Cell Type RNA - Peritubular cells [nTPM]":"18.0","Single Cell Type RNA - Plasma cells [nTPM]":"85.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"40.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"49.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"43.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"30.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.9","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.1","Single Cell Type RNA - Spermatocytes [nTPM]":"36.5","Single Cell Type RNA - Spermatogonia [nTPM]":"39.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"66.5","Single Cell Type RNA - T-cells [nTPM]":"47.3","Single Cell Type RNA - Theca cells [nTPM]":"21.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"36.6","Single Cell Type RNA - Urothelial cells [nTPM]":"43.0"},{"Gene":"ATL1","Gene synonym":["AD-FSP","FSP1","SPG3","SPG3A"],"Ensembl":"ENSG00000198513","Gene description":"Atlastin GTPase 1","Uniprot":["Q8WXF7"],"Chromosome":"14","Position":"50532509-50634017","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"42.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"138.6","Inhibitory neurons":"95.5","Oligodendrocyte precursor cells":"81.4","Oligodendrocytes":"136.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"22.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"22.9"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"19.8","SCLC-21H":"17.1","SH-SY5Y":"15.4","SiHa":"18.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027550"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA027550":"AB_10600983"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.1","Tissue RNA - adrenal gland [nTPM]":"5.6","Tissue RNA - amygdala [nTPM]":"29.1","Tissue RNA - appendix [nTPM]":"3.3","Tissue RNA - basal ganglia [nTPM]":"33.2","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"11.3","Tissue RNA - cerebellum [nTPM]":"18.8","Tissue RNA - cerebral cortex [nTPM]":"42.8","Tissue RNA - cervix [nTPM]":"5.7","Tissue RNA - choroid plexus [nTPM]":"2.2","Tissue RNA - colon [nTPM]":"8.1","Tissue RNA - duodenum [nTPM]":"3.9","Tissue RNA - endometrium 1 [nTPM]":"9.0","Tissue RNA - epididymis [nTPM]":"2.9","Tissue RNA - esophagus [nTPM]":"5.3","Tissue RNA - fallopian tube [nTPM]":"6.5","Tissue RNA - gallbladder [nTPM]":"4.8","Tissue RNA - heart muscle [nTPM]":"2.1","Tissue RNA - hippocampal formation [nTPM]":"37.1","Tissue RNA - hypothalamus [nTPM]":"30.3","Tissue RNA - kidney [nTPM]":"4.0","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"4.3","Tissue RNA - lymph node [nTPM]":"1.7","Tissue RNA - medulla oblongata [nTPM]":"25.2","Tissue RNA - midbrain [nTPM]":"21.5","Tissue RNA - ovary [nTPM]":"10.5","Tissue RNA - pancreas [nTPM]":"3.7","Tissue RNA - parathyroid gland [nTPM]":"1.9","Tissue RNA - pituitary gland [nTPM]":"7.7","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"29.6","Tissue RNA - prostate [nTPM]":"8.3","Tissue RNA - rectum [nTPM]":"5.6","Tissue RNA - retina [nTPM]":"9.5","Tissue RNA - salivary gland [nTPM]":"13.2","Tissue RNA - seminal vesicle [nTPM]":"8.6","Tissue RNA - skeletal muscle [nTPM]":"1.1","Tissue RNA - skin 1 [nTPM]":"9.6","Tissue RNA - small intestine [nTPM]":"4.9","Tissue RNA - smooth muscle [nTPM]":"15.6","Tissue RNA - spinal cord [nTPM]":"24.9","Tissue RNA - spleen [nTPM]":"1.1","Tissue RNA - stomach 1 [nTPM]":"4.6","Tissue RNA - testis [nTPM]":"8.7","Tissue RNA - thalamus [nTPM]":"25.0","Tissue RNA - thymus [nTPM]":"1.1","Tissue RNA - thyroid gland [nTPM]":"2.5","Tissue RNA - tongue [nTPM]":"2.2","Tissue RNA - tonsil [nTPM]":"1.8","Tissue RNA - urinary bladder [nTPM]":"6.7","Tissue RNA - vagina [nTPM]":"5.3","Tissue RNA - white matter [nTPM]":"30.0","Cell RNA - A-431 [nTPM]":"1.2","Cell RNA - A549 [nTPM]":"1.1","Cell RNA - AF22 [nTPM]":"4.8","Cell RNA - AN3-CA [nTPM]":"4.6","Cell RNA - ASC diff [nTPM]":"0.3","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"3.4","Cell RNA - BJ [nTPM]":"5.7","Cell RNA - BJ hTERT+ [nTPM]":"9.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.4","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"4.1","Cell RNA - Daudi [nTPM]":"3.7","Cell RNA - EFO-21 [nTPM]":"2.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"4.5","Cell RNA - HaCaT [nTPM]":"1.4","Cell RNA - HAP1 [nTPM]":"8.4","Cell RNA - HBEC3-KT [nTPM]":"1.1","Cell RNA - HBF TERT88 [nTPM]":"2.4","Cell RNA - HDLM-2 [nTPM]":"19.8","Cell RNA - HEK 293 [nTPM]":"1.8","Cell RNA - HEL [nTPM]":"1.2","Cell RNA - HeLa [nTPM]":"0.8","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"3.1","Cell RNA - HSkMC [nTPM]":"3.6","Cell RNA - hTCEpi [nTPM]":"1.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.6","Cell RNA - hTERT-HME1 [nTPM]":"1.6","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.4","Cell RNA - JURKAT [nTPM]":"4.2","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"8.7","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"1.2","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"4.4","Cell RNA - OE19 [nTPM]":"1.4","Cell RNA - PC-3 [nTPM]":"1.5","Cell RNA - REH [nTPM]":"0.6","Cell RNA - RH-30 [nTPM]":"12.1","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"1.7","Cell RNA - RT4 [nTPM]":"2.5","Cell RNA - SCLC-21H [nTPM]":"17.1","Cell RNA - SH-SY5Y [nTPM]":"15.4","Cell RNA - SiHa [nTPM]":"18.9","Cell RNA - SK-BR-3 [nTPM]":"1.1","Cell RNA - SK-MEL-30 [nTPM]":"0.6","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"2.1","Cell RNA - TIME [nTPM]":"1.3","Cell RNA - U-138 MG [nTPM]":"6.0","Cell RNA - U-2 OS [nTPM]":"4.6","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"2.9","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"4.7","Cell RNA - U-698 [nTPM]":"1.7","Cell RNA - U-87 MG [nTPM]":"3.9","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"22.9","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"4.9","Blood RNA - gdT-cell [nTPM]":"2.5","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"3.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"2.1","Blood RNA - myeloid DC [nTPM]":"1.2","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"2.1","Blood RNA - naive CD8 T-cell [nTPM]":"4.2","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"2.8","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"2.0","Brain RNA - amygdala [nTPM]":"29.1","Brain RNA - basal ganglia [nTPM]":"33.2","Brain RNA - cerebellum [nTPM]":"18.8","Brain RNA - cerebral cortex [nTPM]":"42.8","Brain RNA - hippocampal formation [nTPM]":"37.1","Brain RNA - hypothalamus [nTPM]":"30.3","Brain RNA - medulla oblongata [nTPM]":"25.2","Brain RNA - midbrain [nTPM]":"21.5","Brain RNA - pons [nTPM]":"29.6","Brain RNA - spinal cord [nTPM]":"24.9","Brain RNA - thalamus [nTPM]":"25.0","Brain RNA - white matter [nTPM]":"30.0","Single Cell Type RNA - Adipocytes [nTPM]":"3.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.6","Single Cell Type RNA - Astrocytes [nTPM]":"31.6","Single Cell Type RNA - B-cells [nTPM]":"3.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"27.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"6.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"6.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"10.6","Single Cell Type RNA - Early spermatids [nTPM]":"31.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.4","Single Cell Type RNA - Endothelial cells [nTPM]":"4.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"138.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.1","Single Cell Type RNA - Fibroblasts [nTPM]":"14.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.3","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"1.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.6","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"95.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.9","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"3.6","Single Cell Type RNA - Late spermatids [nTPM]":"5.7","Single Cell Type RNA - Leydig cells [nTPM]":"13.4","Single Cell Type RNA - Macrophages [nTPM]":"5.5","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"1.3","Single Cell Type RNA - Muller glia cells [nTPM]":"23.0","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"81.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"136.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.2","Single Cell Type RNA - Paneth cells [nTPM]":"6.0","Single Cell Type RNA - Peritubular cells [nTPM]":"17.0","Single Cell Type RNA - Plasma cells [nTPM]":"5.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.6","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.8","Single Cell Type RNA - Spermatocytes [nTPM]":"31.9","Single Cell Type RNA - Spermatogonia [nTPM]":"5.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"3.8","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.6","Single Cell Type RNA - Urothelial cells [nTPM]":"3.3"},{"Gene":"ATL3","Gene synonym":["DKFZP564J0863"],"Ensembl":"ENSG00000184743","Gene description":"Atlastin GTPase 3","Uniprot":["Q6DD88"],"Chromosome":"11","Position":"63624087-63671921","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Early spermatids":"264.4","Late spermatids":"728.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065702","HPA076616"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"58000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA065702":"AB_2685536","HPA076616":"AB_2732318"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.04e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-3"},"Tissue RNA - adipose tissue [nTPM]":"30.6","Tissue RNA - adrenal gland [nTPM]":"18.1","Tissue RNA - amygdala [nTPM]":"11.6","Tissue RNA - appendix [nTPM]":"17.9","Tissue RNA - basal ganglia [nTPM]":"16.6","Tissue RNA - bone marrow [nTPM]":"13.2","Tissue RNA - breast [nTPM]":"22.1","Tissue RNA - cerebellum [nTPM]":"14.9","Tissue RNA - cerebral cortex [nTPM]":"12.6","Tissue RNA - cervix [nTPM]":"23.0","Tissue RNA - choroid plexus [nTPM]":"22.0","Tissue RNA - colon [nTPM]":"26.0","Tissue RNA - duodenum [nTPM]":"9.9","Tissue RNA - endometrium 1 [nTPM]":"24.3","Tissue RNA - epididymis [nTPM]":"16.5","Tissue RNA - esophagus [nTPM]":"24.5","Tissue RNA - fallopian tube [nTPM]":"20.1","Tissue RNA - gallbladder [nTPM]":"15.9","Tissue RNA - heart muscle [nTPM]":"11.5","Tissue RNA - hippocampal formation [nTPM]":"9.8","Tissue RNA - hypothalamus [nTPM]":"13.9","Tissue RNA - kidney [nTPM]":"12.6","Tissue RNA - liver [nTPM]":"17.7","Tissue RNA - lung [nTPM]":"18.8","Tissue RNA - lymph node [nTPM]":"12.6","Tissue RNA - medulla oblongata [nTPM]":"19.8","Tissue RNA - midbrain [nTPM]":"16.4","Tissue RNA - ovary [nTPM]":"16.9","Tissue RNA - pancreas [nTPM]":"15.4","Tissue RNA - parathyroid gland [nTPM]":"13.3","Tissue RNA - pituitary gland [nTPM]":"6.6","Tissue RNA - placenta [nTPM]":"14.9","Tissue RNA - pons [nTPM]":"18.9","Tissue RNA - prostate [nTPM]":"16.7","Tissue RNA - rectum [nTPM]":"16.6","Tissue RNA - retina [nTPM]":"4.0","Tissue RNA - salivary gland [nTPM]":"15.4","Tissue RNA - seminal vesicle [nTPM]":"20.4","Tissue RNA - skeletal muscle [nTPM]":"6.3","Tissue RNA - skin 1 [nTPM]":"25.2","Tissue RNA - small intestine [nTPM]":"13.7","Tissue RNA - smooth muscle [nTPM]":"33.2","Tissue RNA - spinal cord [nTPM]":"16.8","Tissue RNA - spleen [nTPM]":"16.9","Tissue RNA - stomach 1 [nTPM]":"17.4","Tissue RNA - testis [nTPM]":"36.9","Tissue RNA - thalamus [nTPM]":"15.5","Tissue RNA - thymus [nTPM]":"10.8","Tissue RNA - thyroid gland [nTPM]":"20.9","Tissue RNA - tongue [nTPM]":"9.6","Tissue RNA - tonsil [nTPM]":"15.4","Tissue RNA - urinary bladder [nTPM]":"27.1","Tissue RNA - vagina [nTPM]":"19.4","Tissue RNA - white matter [nTPM]":"20.6","Cell RNA - A-431 [nTPM]":"44.2","Cell RNA - A549 [nTPM]":"39.4","Cell RNA - AF22 [nTPM]":"11.7","Cell RNA - AN3-CA [nTPM]":"28.4","Cell RNA - ASC diff [nTPM]":"59.2","Cell RNA - ASC TERT1 [nTPM]":"82.5","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"53.2","Cell RNA - BJ hTERT+ [nTPM]":"60.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"51.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"35.0","Cell RNA - CACO-2 [nTPM]":"32.9","Cell RNA - CAPAN-2 [nTPM]":"69.7","Cell RNA - Daudi [nTPM]":"26.3","Cell RNA - EFO-21 [nTPM]":"53.8","Cell RNA - fHDF\/TERT166 [nTPM]":"93.6","Cell RNA - GAMG [nTPM]":"40.0","Cell RNA - HaCaT [nTPM]":"28.3","Cell RNA - HAP1 [nTPM]":"21.8","Cell RNA - HBEC3-KT [nTPM]":"34.8","Cell RNA - HBF TERT88 [nTPM]":"69.8","Cell RNA - HDLM-2 [nTPM]":"40.4","Cell RNA - HEK 293 [nTPM]":"5.8","Cell RNA - HEL [nTPM]":"27.9","Cell RNA - HeLa [nTPM]":"41.8","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"40.7","Cell RNA - HL-60 [nTPM]":"53.2","Cell RNA - HMC-1 [nTPM]":"39.2","Cell RNA - HSkMC [nTPM]":"54.0","Cell RNA - hTCEpi [nTPM]":"55.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"69.1","Cell RNA - hTERT-HME1 [nTPM]":"42.8","Cell RNA - hTERT-RPE1 [nTPM]":"34.7","Cell RNA - HUVEC TERT2 [nTPM]":"56.3","Cell RNA - JURKAT [nTPM]":"28.5","Cell RNA - K-562 [nTPM]":"30.6","Cell RNA - Karpas-707 [nTPM]":"70.2","Cell RNA - LHCN-M2 [nTPM]":"59.6","Cell RNA - MCF7 [nTPM]":"46.6","Cell RNA - MOLT-4 [nTPM]":"19.2","Cell RNA - NB-4 [nTPM]":"30.7","Cell RNA - NTERA-2 [nTPM]":"14.9","Cell RNA - OE19 [nTPM]":"14.1","Cell RNA - PC-3 [nTPM]":"33.7","Cell RNA - REH [nTPM]":"40.7","Cell RNA - RH-30 [nTPM]":"29.3","Cell RNA - RPMI-8226 [nTPM]":"37.8","Cell RNA - RPTEC TERT1 [nTPM]":"41.2","Cell RNA - RT4 [nTPM]":"29.7","Cell RNA - SCLC-21H [nTPM]":"6.3","Cell RNA - SH-SY5Y [nTPM]":"17.0","Cell RNA - SiHa [nTPM]":"174.3","Cell RNA - SK-BR-3 [nTPM]":"37.6","Cell RNA - SK-MEL-30 [nTPM]":"50.5","Cell RNA - SuSa [nTPM]":"14.5","Cell RNA - T-47d [nTPM]":"65.7","Cell RNA - THP-1 [nTPM]":"19.1","Cell RNA - TIME [nTPM]":"79.1","Cell RNA - U-138 MG [nTPM]":"109.0","Cell RNA - U-2 OS [nTPM]":"51.9","Cell RNA - U-2197 [nTPM]":"105.3","Cell RNA - U-251 MG [nTPM]":"38.3","Cell RNA - U-266\/70 [nTPM]":"19.0","Cell RNA - U-266\/84 [nTPM]":"29.6","Cell RNA - U-698 [nTPM]":"51.4","Cell RNA - U-87 MG [nTPM]":"57.7","Cell RNA - U-937 [nTPM]":"33.6","Cell RNA - WM-115 [nTPM]":"67.1","Blood RNA - basophil [nTPM]":"7.1","Blood RNA - classical monocyte [nTPM]":"8.3","Blood RNA - eosinophil [nTPM]":"3.7","Blood RNA - gdT-cell [nTPM]":"8.9","Blood RNA - intermediate monocyte [nTPM]":"11.4","Blood RNA - MAIT T-cell [nTPM]":"9.8","Blood RNA - memory B-cell [nTPM]":"5.3","Blood RNA - memory CD4 T-cell [nTPM]":"7.4","Blood RNA - memory CD8 T-cell [nTPM]":"7.3","Blood RNA - myeloid DC [nTPM]":"8.6","Blood RNA - naive B-cell [nTPM]":"4.2","Blood RNA - naive CD4 T-cell [nTPM]":"5.9","Blood RNA - naive CD8 T-cell [nTPM]":"8.2","Blood RNA - neutrophil [nTPM]":"3.5","Blood RNA - NK-cell [nTPM]":"6.9","Blood RNA - non-classical monocyte [nTPM]":"13.4","Blood RNA - plasmacytoid DC [nTPM]":"4.3","Blood RNA - T-reg [nTPM]":"9.3","Blood RNA - total PBMC [nTPM]":"7.8","Brain RNA - amygdala [nTPM]":"11.6","Brain RNA - basal ganglia [nTPM]":"16.6","Brain RNA - cerebellum [nTPM]":"14.9","Brain RNA - cerebral cortex [nTPM]":"12.6","Brain RNA - hippocampal formation [nTPM]":"9.8","Brain RNA - hypothalamus [nTPM]":"13.9","Brain RNA - medulla oblongata [nTPM]":"19.8","Brain RNA - midbrain [nTPM]":"16.4","Brain RNA - pons [nTPM]":"18.9","Brain RNA - spinal cord [nTPM]":"16.8","Brain RNA - thalamus [nTPM]":"15.5","Brain RNA - white matter [nTPM]":"20.6","Single Cell Type RNA - Adipocytes [nTPM]":"56.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.2","Single Cell Type RNA - Astrocytes [nTPM]":"16.6","Single Cell Type RNA - B-cells [nTPM]":"18.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"43.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"45.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"36.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"30.1","Single Cell Type RNA - Bipolar cells [nTPM]":"4.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"31.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"29.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.7","Single Cell Type RNA - dendritic cells [nTPM]":"28.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"45.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"41.2","Single Cell Type RNA - Early spermatids [nTPM]":"264.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"46.4","Single Cell Type RNA - Endothelial cells [nTPM]":"48.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.7","Single Cell Type RNA - Erythroid cells [nTPM]":"29.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"50.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.1","Single Cell Type RNA - Fibroblasts [nTPM]":"46.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"63.8","Single Cell Type RNA - granulocytes [nTPM]":"17.1","Single Cell Type RNA - Granulosa cells [nTPM]":"20.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"49.6","Single Cell Type RNA - Hepatocytes [nTPM]":"51.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"37.6","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.0","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"55.3","Single Cell Type RNA - Langerhans cells [nTPM]":"43.0","Single Cell Type RNA - Late spermatids [nTPM]":"728.4","Single Cell Type RNA - Leydig cells [nTPM]":"54.3","Single Cell Type RNA - Macrophages [nTPM]":"35.7","Single Cell Type RNA - Melanocytes [nTPM]":"42.7","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"49.5","Single Cell Type RNA - Muller glia cells [nTPM]":"12.6","Single Cell Type RNA - NK-cells [nTPM]":"24.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"35.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"72.7","Single Cell Type RNA - Paneth cells [nTPM]":"24.7","Single Cell Type RNA - Peritubular cells [nTPM]":"67.4","Single Cell Type RNA - Plasma cells [nTPM]":"21.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"55.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"27.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"24.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.5","Single Cell Type RNA - Sertoli cells [nTPM]":"72.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"35.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"55.2","Single Cell Type RNA - Spermatocytes [nTPM]":"36.0","Single Cell Type RNA - Spermatogonia [nTPM]":"29.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"32.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"40.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.0","Single Cell Type RNA - T-cells [nTPM]":"28.2","Single Cell Type RNA - Theca cells [nTPM]":"25.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.8","Single Cell Type RNA - Urothelial cells [nTPM]":"50.9"},{"Gene":"ATM","Gene synonym":["ATA","ATC","ATD","ATDC","TEL1","TELO1"],"Ensembl":"ENSG00000149311","Gene description":"ATM serine\/threonine kinase","Uniprot":["Q13315"],"Chromosome":"11","Position":"108222832-108369102","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA damage"],"Molecular function":["DNA-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Neurodegeneration","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"210.6","NK-cells":"339.8","Oligodendrocytes":"217.6","Rod photoreceptor cells":"200.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-698":"78.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000102","HPA067142"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB000102":null,"HPA067142":"AB_2685789"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.2","Tissue RNA - adrenal gland [nTPM]":"7.4","Tissue RNA - amygdala [nTPM]":"8.2","Tissue RNA - appendix [nTPM]":"17.5","Tissue RNA - basal ganglia [nTPM]":"15.0","Tissue RNA - bone marrow [nTPM]":"16.2","Tissue RNA - breast [nTPM]":"8.5","Tissue RNA - cerebellum [nTPM]":"17.0","Tissue RNA - cerebral cortex [nTPM]":"12.3","Tissue RNA - cervix [nTPM]":"8.7","Tissue RNA - choroid plexus [nTPM]":"16.1","Tissue RNA - colon [nTPM]":"6.7","Tissue RNA - duodenum [nTPM]":"5.2","Tissue RNA - endometrium 1 [nTPM]":"10.0","Tissue RNA - epididymis [nTPM]":"9.9","Tissue RNA - esophagus [nTPM]":"4.0","Tissue RNA - fallopian tube [nTPM]":"7.5","Tissue RNA - gallbladder [nTPM]":"8.2","Tissue RNA - heart muscle [nTPM]":"7.0","Tissue RNA - hippocampal formation [nTPM]":"7.3","Tissue RNA - hypothalamus [nTPM]":"11.3","Tissue RNA - kidney [nTPM]":"5.8","Tissue RNA - liver [nTPM]":"7.8","Tissue RNA - lung [nTPM]":"7.6","Tissue RNA - lymph node [nTPM]":"33.7","Tissue RNA - medulla oblongata [nTPM]":"15.8","Tissue RNA - midbrain [nTPM]":"13.1","Tissue RNA - ovary [nTPM]":"15.8","Tissue RNA - pancreas [nTPM]":"14.8","Tissue RNA - parathyroid gland [nTPM]":"9.3","Tissue RNA - pituitary gland [nTPM]":"12.1","Tissue RNA - placenta [nTPM]":"8.0","Tissue RNA - pons [nTPM]":"17.0","Tissue RNA - prostate [nTPM]":"6.3","Tissue RNA - rectum [nTPM]":"7.0","Tissue RNA - retina [nTPM]":"20.6","Tissue RNA - salivary gland [nTPM]":"11.4","Tissue RNA - seminal vesicle [nTPM]":"6.1","Tissue RNA - skeletal muscle [nTPM]":"4.4","Tissue RNA - skin 1 [nTPM]":"7.5","Tissue RNA - small intestine [nTPM]":"12.6","Tissue RNA - smooth muscle [nTPM]":"6.9","Tissue RNA - spinal cord [nTPM]":"10.3","Tissue RNA - spleen [nTPM]":"22.2","Tissue RNA - stomach 1 [nTPM]":"8.6","Tissue RNA - testis [nTPM]":"5.2","Tissue RNA - thalamus [nTPM]":"12.7","Tissue RNA - thymus [nTPM]":"18.2","Tissue RNA - thyroid gland [nTPM]":"8.8","Tissue RNA - tongue [nTPM]":"6.0","Tissue RNA - tonsil [nTPM]":"25.9","Tissue RNA - urinary bladder [nTPM]":"7.1","Tissue RNA - vagina [nTPM]":"6.9","Tissue RNA - white matter [nTPM]":"28.8","Cell RNA - A-431 [nTPM]":"4.3","Cell RNA - A549 [nTPM]":"6.8","Cell RNA - AF22 [nTPM]":"14.8","Cell RNA - AN3-CA [nTPM]":"7.6","Cell RNA - ASC diff [nTPM]":"20.2","Cell RNA - ASC TERT1 [nTPM]":"29.1","Cell RNA - BEWO [nTPM]":"3.1","Cell RNA - BJ [nTPM]":"10.9","Cell RNA - BJ hTERT+ [nTPM]":"13.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.3","Cell RNA - CACO-2 [nTPM]":"7.1","Cell RNA - CAPAN-2 [nTPM]":"10.3","Cell RNA - Daudi [nTPM]":"18.3","Cell RNA - EFO-21 [nTPM]":"14.0","Cell RNA - fHDF\/TERT166 [nTPM]":"10.2","Cell RNA - GAMG [nTPM]":"9.6","Cell RNA - HaCaT [nTPM]":"7.7","Cell RNA - HAP1 [nTPM]":"11.6","Cell RNA - HBEC3-KT [nTPM]":"10.8","Cell RNA - HBF TERT88 [nTPM]":"9.0","Cell RNA - HDLM-2 [nTPM]":"12.3","Cell RNA - HEK 293 [nTPM]":"5.7","Cell RNA - HEL [nTPM]":"15.2","Cell RNA - HeLa [nTPM]":"8.7","Cell RNA - Hep G2 [nTPM]":"10.2","Cell RNA - HHSteC [nTPM]":"10.5","Cell RNA - HL-60 [nTPM]":"16.4","Cell RNA - HMC-1 [nTPM]":"17.0","Cell RNA - HSkMC [nTPM]":"18.3","Cell RNA - hTCEpi [nTPM]":"6.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.0","Cell RNA - hTERT-HME1 [nTPM]":"21.2","Cell RNA - hTERT-RPE1 [nTPM]":"15.2","Cell RNA - HUVEC TERT2 [nTPM]":"14.1","Cell RNA - JURKAT [nTPM]":"16.5","Cell RNA - K-562 [nTPM]":"12.4","Cell RNA - Karpas-707 [nTPM]":"9.9","Cell RNA - LHCN-M2 [nTPM]":"14.3","Cell RNA - MCF7 [nTPM]":"3.4","Cell RNA - MOLT-4 [nTPM]":"10.6","Cell RNA - NB-4 [nTPM]":"18.5","Cell RNA - NTERA-2 [nTPM]":"9.8","Cell RNA - OE19 [nTPM]":"8.6","Cell RNA - PC-3 [nTPM]":"7.4","Cell RNA - REH [nTPM]":"9.7","Cell RNA - RH-30 [nTPM]":"9.7","Cell RNA - RPMI-8226 [nTPM]":"24.9","Cell RNA - RPTEC TERT1 [nTPM]":"8.1","Cell RNA - RT4 [nTPM]":"7.5","Cell RNA - SCLC-21H [nTPM]":"9.0","Cell RNA - SH-SY5Y [nTPM]":"10.5","Cell RNA - SiHa [nTPM]":"11.1","Cell RNA - SK-BR-3 [nTPM]":"4.7","Cell RNA - SK-MEL-30 [nTPM]":"20.6","Cell RNA - SuSa [nTPM]":"13.2","Cell RNA - T-47d [nTPM]":"9.3","Cell RNA - THP-1 [nTPM]":"10.1","Cell RNA - TIME [nTPM]":"23.7","Cell RNA - U-138 MG [nTPM]":"15.8","Cell RNA - U-2 OS [nTPM]":"8.4","Cell RNA - U-2197 [nTPM]":"7.3","Cell RNA - U-251 MG [nTPM]":"9.0","Cell RNA - U-266\/70 [nTPM]":"6.2","Cell RNA - U-266\/84 [nTPM]":"7.0","Cell RNA - U-698 [nTPM]":"78.3","Cell RNA - U-87 MG [nTPM]":"7.0","Cell RNA - U-937 [nTPM]":"19.0","Cell RNA - WM-115 [nTPM]":"18.8","Blood RNA - basophil [nTPM]":"21.3","Blood RNA - classical monocyte [nTPM]":"5.5","Blood RNA - eosinophil [nTPM]":"4.0","Blood RNA - gdT-cell [nTPM]":"16.5","Blood RNA - intermediate monocyte [nTPM]":"5.7","Blood RNA - MAIT T-cell [nTPM]":"11.1","Blood RNA - memory B-cell [nTPM]":"11.6","Blood RNA - memory CD4 T-cell [nTPM]":"11.7","Blood RNA - memory CD8 T-cell [nTPM]":"12.5","Blood RNA - myeloid DC [nTPM]":"2.6","Blood RNA - naive B-cell [nTPM]":"13.0","Blood RNA - naive CD4 T-cell [nTPM]":"21.1","Blood RNA - naive CD8 T-cell [nTPM]":"20.4","Blood RNA - neutrophil [nTPM]":"9.9","Blood RNA - NK-cell [nTPM]":"9.7","Blood RNA - non-classical monocyte [nTPM]":"13.3","Blood RNA - plasmacytoid DC [nTPM]":"6.2","Blood RNA - T-reg [nTPM]":"6.1","Blood RNA - total PBMC [nTPM]":"5.3","Brain RNA - amygdala [nTPM]":"8.2","Brain RNA - basal ganglia [nTPM]":"15.0","Brain RNA - cerebellum [nTPM]":"17.0","Brain RNA - cerebral cortex [nTPM]":"12.3","Brain RNA - hippocampal formation [nTPM]":"7.3","Brain RNA - hypothalamus [nTPM]":"11.3","Brain RNA - medulla oblongata [nTPM]":"15.8","Brain RNA - midbrain [nTPM]":"13.1","Brain RNA - pons [nTPM]":"17.0","Brain RNA - spinal cord [nTPM]":"10.3","Brain RNA - thalamus [nTPM]":"12.7","Brain RNA - white matter [nTPM]":"28.8","Single Cell Type RNA - Adipocytes [nTPM]":"23.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.8","Single Cell Type RNA - Astrocytes [nTPM]":"62.7","Single Cell Type RNA - B-cells [nTPM]":"146.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"28.5","Single Cell Type RNA - Bipolar cells [nTPM]":"111.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"39.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"19.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"210.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.9","Single Cell Type RNA - dendritic cells [nTPM]":"140.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.9","Single Cell Type RNA - Early spermatids [nTPM]":"19.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"52.1","Single Cell Type RNA - Endothelial cells [nTPM]":"25.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.4","Single Cell Type RNA - Erythroid cells [nTPM]":"39.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"70.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.2","Single Cell Type RNA - Fibroblasts [nTPM]":"39.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.9","Single Cell Type RNA - granulocytes [nTPM]":"13.3","Single Cell Type RNA - Granulosa cells [nTPM]":"45.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.9","Single Cell Type RNA - Hepatocytes [nTPM]":"23.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"29.1","Single Cell Type RNA - Horizontal cells [nTPM]":"60.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"82.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.9","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"96.4","Single Cell Type RNA - Langerhans cells [nTPM]":"34.0","Single Cell Type RNA - Late spermatids [nTPM]":"5.1","Single Cell Type RNA - Leydig cells [nTPM]":"39.4","Single Cell Type RNA - Macrophages [nTPM]":"69.2","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"178.9","Single Cell Type RNA - monocytes [nTPM]":"63.2","Single Cell Type RNA - Muller glia cells [nTPM]":"27.3","Single Cell Type RNA - NK-cells [nTPM]":"339.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"85.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"217.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.6","Single Cell Type RNA - Paneth cells [nTPM]":"7.6","Single Cell Type RNA - Peritubular cells [nTPM]":"27.8","Single Cell Type RNA - Plasma cells [nTPM]":"96.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"200.1","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"41.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"29.2","Single Cell Type RNA - Spermatocytes [nTPM]":"31.5","Single Cell Type RNA - Spermatogonia [nTPM]":"37.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.2","Single Cell Type RNA - T-cells [nTPM]":"147.7","Single Cell Type RNA - Theca cells [nTPM]":"52.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.5","Single Cell Type RNA - Urothelial cells [nTPM]":"10.2"},{"Gene":"ATP11C","Gene synonym":["ATPIG","ATPIQ"],"Ensembl":"ENSG00000101974","Gene description":"ATPase phospholipid transporting 11C","Uniprot":["Q8NB49"],"Chromosome":"X","Position":"139726346-139945276","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Hereditary hemolytic anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"49.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"67.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"15.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030830"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA030830":"AB_10601336"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Tissue RNA - adipose tissue [nTPM]":"13.4","Tissue RNA - adrenal gland [nTPM]":"7.4","Tissue RNA - amygdala [nTPM]":"3.5","Tissue RNA - appendix [nTPM]":"9.0","Tissue RNA - basal ganglia [nTPM]":"4.2","Tissue RNA - bone marrow [nTPM]":"6.1","Tissue RNA - breast [nTPM]":"10.4","Tissue RNA - cerebellum [nTPM]":"3.6","Tissue RNA - cerebral cortex [nTPM]":"4.6","Tissue RNA - cervix [nTPM]":"11.8","Tissue RNA - choroid plexus [nTPM]":"10.3","Tissue RNA - colon [nTPM]":"10.0","Tissue RNA - duodenum [nTPM]":"5.6","Tissue RNA - endometrium 1 [nTPM]":"11.9","Tissue RNA - epididymis [nTPM]":"9.3","Tissue RNA - esophagus [nTPM]":"5.1","Tissue RNA - fallopian tube [nTPM]":"10.7","Tissue RNA - gallbladder [nTPM]":"8.4","Tissue RNA - heart muscle [nTPM]":"5.4","Tissue RNA - hippocampal formation [nTPM]":"3.1","Tissue RNA - hypothalamus [nTPM]":"4.5","Tissue RNA - kidney [nTPM]":"11.8","Tissue RNA - liver [nTPM]":"49.8","Tissue RNA - lung [nTPM]":"7.2","Tissue RNA - lymph node [nTPM]":"14.8","Tissue RNA - medulla oblongata [nTPM]":"4.9","Tissue RNA - midbrain [nTPM]":"4.7","Tissue RNA - ovary [nTPM]":"12.7","Tissue RNA - pancreas [nTPM]":"4.9","Tissue RNA - parathyroid gland [nTPM]":"5.7","Tissue RNA - pituitary gland [nTPM]":"3.7","Tissue RNA - placenta [nTPM]":"5.3","Tissue RNA - pons [nTPM]":"5.2","Tissue RNA - prostate [nTPM]":"9.8","Tissue RNA - rectum [nTPM]":"7.1","Tissue RNA - retina [nTPM]":"2.8","Tissue RNA - salivary gland [nTPM]":"6.0","Tissue RNA - seminal vesicle [nTPM]":"14.6","Tissue RNA - skeletal muscle [nTPM]":"3.5","Tissue RNA - skin 1 [nTPM]":"6.0","Tissue RNA - small intestine [nTPM]":"8.6","Tissue RNA - smooth muscle [nTPM]":"10.6","Tissue RNA - spinal cord [nTPM]":"3.9","Tissue RNA - spleen [nTPM]":"12.2","Tissue RNA - stomach 1 [nTPM]":"7.6","Tissue RNA - testis [nTPM]":"9.7","Tissue RNA - thalamus [nTPM]":"4.8","Tissue RNA - thymus [nTPM]":"11.1","Tissue RNA - thyroid gland [nTPM]":"6.1","Tissue RNA - tongue [nTPM]":"4.3","Tissue RNA - tonsil [nTPM]":"8.8","Tissue RNA - urinary bladder [nTPM]":"13.6","Tissue RNA - vagina [nTPM]":"9.3","Tissue RNA - white matter [nTPM]":"4.5","Cell RNA - A-431 [nTPM]":"16.9","Cell RNA - A549 [nTPM]":"7.1","Cell RNA - AF22 [nTPM]":"14.2","Cell RNA - AN3-CA [nTPM]":"23.3","Cell RNA - ASC diff [nTPM]":"20.7","Cell RNA - ASC TERT1 [nTPM]":"27.9","Cell RNA - BEWO [nTPM]":"18.0","Cell RNA - BJ [nTPM]":"19.7","Cell RNA - BJ hTERT+ [nTPM]":"26.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.5","Cell RNA - CACO-2 [nTPM]":"6.3","Cell RNA - CAPAN-2 [nTPM]":"13.4","Cell RNA - Daudi [nTPM]":"24.0","Cell RNA - EFO-21 [nTPM]":"43.3","Cell RNA - fHDF\/TERT166 [nTPM]":"28.2","Cell RNA - GAMG [nTPM]":"10.3","Cell RNA - HaCaT [nTPM]":"13.7","Cell RNA - HAP1 [nTPM]":"34.6","Cell RNA - HBEC3-KT [nTPM]":"9.0","Cell RNA - HBF TERT88 [nTPM]":"24.4","Cell RNA - HDLM-2 [nTPM]":"22.1","Cell RNA - HEK 293 [nTPM]":"20.2","Cell RNA - HEL [nTPM]":"12.1","Cell RNA - HeLa [nTPM]":"15.2","Cell RNA - Hep G2 [nTPM]":"12.3","Cell RNA - HHSteC [nTPM]":"23.0","Cell RNA - HL-60 [nTPM]":"21.4","Cell RNA - HMC-1 [nTPM]":"7.4","Cell RNA - HSkMC [nTPM]":"18.6","Cell RNA - hTCEpi [nTPM]":"5.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.9","Cell RNA - hTERT-HME1 [nTPM]":"14.4","Cell RNA - hTERT-RPE1 [nTPM]":"17.3","Cell RNA - HUVEC TERT2 [nTPM]":"27.3","Cell RNA - JURKAT [nTPM]":"18.3","Cell RNA - K-562 [nTPM]":"14.0","Cell RNA - Karpas-707 [nTPM]":"17.9","Cell RNA - LHCN-M2 [nTPM]":"20.8","Cell RNA - MCF7 [nTPM]":"9.1","Cell RNA - MOLT-4 [nTPM]":"19.7","Cell RNA - NB-4 [nTPM]":"14.5","Cell RNA - NTERA-2 [nTPM]":"24.1","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"13.3","Cell RNA - REH [nTPM]":"19.5","Cell RNA - RH-30 [nTPM]":"15.3","Cell RNA - RPMI-8226 [nTPM]":"20.1","Cell RNA - RPTEC TERT1 [nTPM]":"13.1","Cell RNA - RT4 [nTPM]":"27.6","Cell RNA - SCLC-21H [nTPM]":"11.0","Cell RNA - SH-SY5Y [nTPM]":"18.3","Cell RNA - SiHa [nTPM]":"7.8","Cell RNA - SK-BR-3 [nTPM]":"0.8","Cell RNA - SK-MEL-30 [nTPM]":"10.6","Cell RNA - SuSa [nTPM]":"13.3","Cell RNA - T-47d [nTPM]":"5.8","Cell RNA - THP-1 [nTPM]":"11.7","Cell RNA - TIME [nTPM]":"31.0","Cell RNA - U-138 MG [nTPM]":"21.2","Cell RNA - U-2 OS [nTPM]":"6.9","Cell RNA - U-2197 [nTPM]":"25.9","Cell RNA - U-251 MG [nTPM]":"27.1","Cell RNA - U-266\/70 [nTPM]":"5.1","Cell RNA - U-266\/84 [nTPM]":"5.4","Cell RNA - U-698 [nTPM]":"18.7","Cell RNA - U-87 MG [nTPM]":"9.7","Cell RNA - U-937 [nTPM]":"26.3","Cell RNA - WM-115 [nTPM]":"10.8","Blood RNA - basophil [nTPM]":"2.4","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"0.9","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"1.2","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"3.5","Brain RNA - basal ganglia [nTPM]":"4.2","Brain RNA - cerebellum [nTPM]":"3.6","Brain RNA - cerebral cortex [nTPM]":"4.6","Brain RNA - hippocampal formation [nTPM]":"3.1","Brain RNA - hypothalamus [nTPM]":"4.5","Brain RNA - medulla oblongata [nTPM]":"4.9","Brain RNA - midbrain [nTPM]":"4.7","Brain RNA - pons [nTPM]":"5.2","Brain RNA - spinal cord [nTPM]":"3.9","Brain RNA - thalamus [nTPM]":"4.8","Brain RNA - white matter [nTPM]":"4.5","Single Cell Type RNA - Adipocytes [nTPM]":"27.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.4","Single Cell Type RNA - Astrocytes [nTPM]":"22.5","Single Cell Type RNA - B-cells [nTPM]":"14.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"1.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"9.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.3","Single Cell Type RNA - dendritic cells [nTPM]":"11.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.8","Single Cell Type RNA - Early spermatids [nTPM]":"13.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.7","Single Cell Type RNA - Endothelial cells [nTPM]":"32.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.1","Single Cell Type RNA - Erythroid cells [nTPM]":"15.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.6","Single Cell Type RNA - Fibroblasts [nTPM]":"17.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.7","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"23.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"34.6","Single Cell Type RNA - Hepatocytes [nTPM]":"46.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"26.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.4","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"37.2","Single Cell Type RNA - Langerhans cells [nTPM]":"14.4","Single Cell Type RNA - Late spermatids [nTPM]":"11.9","Single Cell Type RNA - Leydig cells [nTPM]":"14.3","Single Cell Type RNA - Macrophages [nTPM]":"15.3","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"45.9","Single Cell Type RNA - monocytes [nTPM]":"33.9","Single Cell Type RNA - Muller glia cells [nTPM]":"3.1","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"29.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"27.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.8","Single Cell Type RNA - Paneth cells [nTPM]":"7.2","Single Cell Type RNA - Peritubular cells [nTPM]":"15.4","Single Cell Type RNA - Plasma cells [nTPM]":"13.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.2","Single Cell Type RNA - Spermatocytes [nTPM]":"67.9","Single Cell Type RNA - Spermatogonia [nTPM]":"53.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.7","Single Cell Type RNA - T-cells [nTPM]":"12.7","Single Cell Type RNA - Theca cells [nTPM]":"11.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.2","Single Cell Type RNA - Urothelial cells [nTPM]":"14.6"},{"Gene":"ATP13A2","Gene synonym":["CLN12","HSA9947","PARK9"],"Ensembl":"ENSG00000159363","Gene description":"ATPase cation transporting 13A2","Uniprot":["Q9NQ11"],"Chromosome":"1","Position":"16985958-17011928","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration","Neuronal ceroid lipofuscinosis","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"112.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"61.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"plasmacytoid DC":"20.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"20.6"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037038","CAB037111","HPA050910","HPA054717"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB037038":"AB_1840715","CAB037111":"AB_1840714","HPA050910":"AB_2681269","HPA054717":"AB_2682583"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.33e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.71e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-3"},"Tissue RNA - adipose tissue [nTPM]":"15.3","Tissue RNA - adrenal gland [nTPM]":"18.6","Tissue RNA - amygdala [nTPM]":"49.7","Tissue RNA - appendix [nTPM]":"20.2","Tissue RNA - basal ganglia [nTPM]":"45.8","Tissue RNA - bone marrow [nTPM]":"11.6","Tissue RNA - breast [nTPM]":"14.3","Tissue RNA - cerebellum [nTPM]":"30.3","Tissue RNA - cerebral cortex [nTPM]":"81.2","Tissue RNA - cervix [nTPM]":"10.6","Tissue RNA - choroid plexus [nTPM]":"3.3","Tissue RNA - colon [nTPM]":"15.9","Tissue RNA - duodenum [nTPM]":"12.7","Tissue RNA - endometrium 1 [nTPM]":"12.1","Tissue RNA - epididymis [nTPM]":"6.6","Tissue RNA - esophagus [nTPM]":"23.6","Tissue RNA - fallopian tube [nTPM]":"9.5","Tissue RNA - gallbladder [nTPM]":"9.3","Tissue RNA - heart muscle [nTPM]":"11.6","Tissue RNA - hippocampal formation [nTPM]":"46.7","Tissue RNA - hypothalamus [nTPM]":"66.0","Tissue RNA - kidney [nTPM]":"16.6","Tissue RNA - liver [nTPM]":"6.2","Tissue RNA - lung [nTPM]":"17.9","Tissue RNA - lymph node [nTPM]":"17.7","Tissue RNA - medulla oblongata [nTPM]":"112.4","Tissue RNA - midbrain [nTPM]":"60.8","Tissue RNA - ovary [nTPM]":"8.7","Tissue RNA - pancreas [nTPM]":"55.7","Tissue RNA - parathyroid gland [nTPM]":"12.9","Tissue RNA - pituitary gland [nTPM]":"57.0","Tissue RNA - placenta [nTPM]":"12.6","Tissue RNA - pons [nTPM]":"110.8","Tissue RNA - prostate [nTPM]":"14.3","Tissue RNA - rectum [nTPM]":"9.8","Tissue RNA - retina [nTPM]":"22.8","Tissue RNA - salivary gland [nTPM]":"27.4","Tissue RNA - seminal vesicle [nTPM]":"7.9","Tissue RNA - skeletal muscle [nTPM]":"17.2","Tissue RNA - skin 1 [nTPM]":"16.5","Tissue RNA - small intestine [nTPM]":"16.7","Tissue RNA - smooth muscle [nTPM]":"8.6","Tissue RNA - spinal cord [nTPM]":"32.0","Tissue RNA - spleen [nTPM]":"26.0","Tissue RNA - stomach 1 [nTPM]":"19.3","Tissue RNA - testis [nTPM]":"10.3","Tissue RNA - thalamus [nTPM]":"64.1","Tissue RNA - thymus [nTPM]":"9.5","Tissue RNA - thyroid gland [nTPM]":"16.7","Tissue RNA - tongue [nTPM]":"5.3","Tissue RNA - tonsil [nTPM]":"10.3","Tissue RNA - urinary bladder [nTPM]":"12.9","Tissue RNA - vagina [nTPM]":"12.1","Tissue RNA - white matter [nTPM]":"44.3","Cell RNA - A-431 [nTPM]":"28.3","Cell RNA - A549 [nTPM]":"27.4","Cell RNA - AF22 [nTPM]":"14.7","Cell RNA - AN3-CA [nTPM]":"60.8","Cell RNA - ASC diff [nTPM]":"13.8","Cell RNA - ASC TERT1 [nTPM]":"12.2","Cell RNA - BEWO [nTPM]":"40.8","Cell RNA - BJ [nTPM]":"15.8","Cell RNA - BJ hTERT+ [nTPM]":"15.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.6","Cell RNA - CACO-2 [nTPM]":"48.9","Cell RNA - CAPAN-2 [nTPM]":"31.4","Cell RNA - Daudi [nTPM]":"12.5","Cell RNA - EFO-21 [nTPM]":"65.9","Cell RNA - fHDF\/TERT166 [nTPM]":"26.9","Cell RNA - GAMG [nTPM]":"14.6","Cell RNA - HaCaT [nTPM]":"43.1","Cell RNA - HAP1 [nTPM]":"32.1","Cell RNA - HBEC3-KT [nTPM]":"59.5","Cell RNA - HBF TERT88 [nTPM]":"6.2","Cell RNA - HDLM-2 [nTPM]":"17.2","Cell RNA - HEK 293 [nTPM]":"58.5","Cell RNA - HEL [nTPM]":"43.7","Cell RNA - HeLa [nTPM]":"28.0","Cell RNA - Hep G2 [nTPM]":"27.2","Cell RNA - HHSteC [nTPM]":"17.5","Cell RNA - HL-60 [nTPM]":"15.6","Cell RNA - HMC-1 [nTPM]":"19.6","Cell RNA - HSkMC [nTPM]":"10.0","Cell RNA - hTCEpi [nTPM]":"31.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"47.1","Cell RNA - hTERT-HME1 [nTPM]":"36.6","Cell RNA - hTERT-RPE1 [nTPM]":"55.0","Cell RNA - HUVEC TERT2 [nTPM]":"32.3","Cell RNA - JURKAT [nTPM]":"32.2","Cell RNA - K-562 [nTPM]":"28.2","Cell RNA - Karpas-707 [nTPM]":"22.6","Cell RNA - LHCN-M2 [nTPM]":"70.2","Cell RNA - MCF7 [nTPM]":"22.2","Cell RNA - MOLT-4 [nTPM]":"18.4","Cell RNA - NB-4 [nTPM]":"8.8","Cell RNA - NTERA-2 [nTPM]":"23.2","Cell RNA - OE19 [nTPM]":"66.3","Cell RNA - PC-3 [nTPM]":"20.0","Cell RNA - REH [nTPM]":"20.0","Cell RNA - RH-30 [nTPM]":"60.1","Cell RNA - RPMI-8226 [nTPM]":"50.7","Cell RNA - RPTEC TERT1 [nTPM]":"19.0","Cell RNA - RT4 [nTPM]":"42.8","Cell RNA - SCLC-21H [nTPM]":"40.9","Cell RNA - SH-SY5Y [nTPM]":"27.4","Cell RNA - SiHa [nTPM]":"73.8","Cell RNA - SK-BR-3 [nTPM]":"87.7","Cell RNA - SK-MEL-30 [nTPM]":"60.2","Cell RNA - SuSa [nTPM]":"18.8","Cell RNA - T-47d [nTPM]":"29.9","Cell RNA - THP-1 [nTPM]":"19.6","Cell RNA - TIME [nTPM]":"34.4","Cell RNA - U-138 MG [nTPM]":"18.0","Cell RNA - U-2 OS [nTPM]":"34.5","Cell RNA - U-2197 [nTPM]":"30.8","Cell RNA - U-251 MG [nTPM]":"33.1","Cell RNA - U-266\/70 [nTPM]":"4.8","Cell RNA - U-266\/84 [nTPM]":"6.1","Cell RNA - U-698 [nTPM]":"14.0","Cell RNA - U-87 MG [nTPM]":"34.6","Cell RNA - U-937 [nTPM]":"85.2","Cell RNA - WM-115 [nTPM]":"30.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.6","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"2.6","Blood RNA - intermediate monocyte [nTPM]":"3.7","Blood RNA - MAIT T-cell [nTPM]":"2.9","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"2.1","Blood RNA - memory CD8 T-cell [nTPM]":"2.2","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"3.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"2.7","Blood RNA - non-classical monocyte [nTPM]":"3.6","Blood RNA - plasmacytoid DC [nTPM]":"20.6","Blood RNA - T-reg [nTPM]":"1.8","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"49.7","Brain RNA - basal ganglia [nTPM]":"45.8","Brain RNA - cerebellum [nTPM]":"30.3","Brain RNA - cerebral cortex [nTPM]":"81.2","Brain RNA - hippocampal formation [nTPM]":"46.7","Brain RNA - hypothalamus [nTPM]":"66.0","Brain RNA - medulla oblongata [nTPM]":"112.4","Brain RNA - midbrain [nTPM]":"60.8","Brain RNA - pons [nTPM]":"110.8","Brain RNA - spinal cord [nTPM]":"32.0","Brain RNA - thalamus [nTPM]":"64.1","Brain RNA - white matter [nTPM]":"44.3","Single Cell Type RNA - Adipocytes [nTPM]":"18.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.2","Single Cell Type RNA - Astrocytes [nTPM]":"14.4","Single Cell Type RNA - B-cells [nTPM]":"8.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"35.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"6.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.8","Single Cell Type RNA - dendritic cells [nTPM]":"33.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"15.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.8","Single Cell Type RNA - Endothelial cells [nTPM]":"14.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.7","Single Cell Type RNA - Erythroid cells [nTPM]":"4.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"53.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"33.6","Single Cell Type RNA - Fibroblasts [nTPM]":"6.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.0","Single Cell Type RNA - granulocytes [nTPM]":"8.9","Single Cell Type RNA - Granulosa cells [nTPM]":"20.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"3.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.4","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"61.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"17.3","Single Cell Type RNA - Langerhans cells [nTPM]":"2.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.7","Single Cell Type RNA - Leydig cells [nTPM]":"5.3","Single Cell Type RNA - Macrophages [nTPM]":"10.1","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"6.1","Single Cell Type RNA - Muller glia cells [nTPM]":"34.0","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"57.0","Single Cell Type RNA - Paneth cells [nTPM]":"49.0","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"5.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"38.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.7","Single Cell Type RNA - Spermatocytes [nTPM]":"13.6","Single Cell Type RNA - Spermatogonia [nTPM]":"16.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.3","Single Cell Type RNA - T-cells [nTPM]":"11.1","Single Cell Type RNA - Theca cells [nTPM]":"4.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"21.7","Single Cell Type RNA - Urothelial cells [nTPM]":"12.8"},{"Gene":"ATP13A4","Gene synonym":["DKFZp761I1011","FLJ37958"],"Ensembl":"ENSG00000127249","Gene description":"ATPase 13A4","Uniprot":["Q4VNC1"],"Chromosome":"3","Position":"193398967-193593111","Protein class":["Disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"64.5","parathyroid gland":"58.4","thyroid gland":"51.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"409.4","Oligodendrocyte precursor cells":"163.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"thyroid cancer":"23.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SCLC-21H":"3.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051932"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA051932":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.91e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.75e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"19.5","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"20.9","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"22.7","Tissue RNA - cerebellum [nTPM]":"18.1","Tissue RNA - cerebral cortex [nTPM]":"20.1","Tissue RNA - cervix [nTPM]":"2.8","Tissue RNA - choroid plexus [nTPM]":"28.2","Tissue RNA - colon [nTPM]":"2.0","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"64.5","Tissue RNA - esophagus [nTPM]":"20.1","Tissue RNA - fallopian tube [nTPM]":"2.4","Tissue RNA - gallbladder [nTPM]":"4.6","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"18.0","Tissue RNA - hypothalamus [nTPM]":"17.0","Tissue RNA - kidney [nTPM]":"0.7","Tissue RNA - liver [nTPM]":"0.6","Tissue RNA - lung [nTPM]":"27.3","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"18.5","Tissue RNA - midbrain [nTPM]":"21.5","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"5.3","Tissue RNA - parathyroid gland [nTPM]":"58.4","Tissue RNA - pituitary gland [nTPM]":"4.8","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"17.9","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"3.4","Tissue RNA - retina [nTPM]":"2.5","Tissue RNA - salivary gland [nTPM]":"7.2","Tissue RNA - seminal vesicle [nTPM]":"2.4","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"16.9","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"15.2","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"9.6","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"21.6","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"51.9","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"4.8","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"6.7","Tissue RNA - white matter [nTPM]":"15.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.8","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"3.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.6","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"19.5","Brain RNA - basal ganglia [nTPM]":"20.9","Brain RNA - cerebellum [nTPM]":"18.1","Brain RNA - cerebral cortex [nTPM]":"20.1","Brain RNA - hippocampal formation [nTPM]":"18.0","Brain RNA - hypothalamus [nTPM]":"17.0","Brain RNA - medulla oblongata [nTPM]":"18.5","Brain RNA - midbrain [nTPM]":"21.5","Brain RNA - pons [nTPM]":"17.9","Brain RNA - spinal cord [nTPM]":"15.2","Brain RNA - thalamus [nTPM]":"21.6","Brain RNA - white matter [nTPM]":"15.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"64.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"30.5","Single Cell Type RNA - Astrocytes [nTPM]":"409.4","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"15.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.4","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"163.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.3","Single Cell Type RNA - Paneth cells [nTPM]":"1.7","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"1.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"ATP1A2","Gene synonym":["FHM2","MHP2"],"Ensembl":"ENSG00000018625","Gene description":"ATPase Na+\/K+ transporting subunit alpha 2","Uniprot":["P50993"],"Chromosome":"1","Position":"160115759-160143591","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Sodium transport","Sodium\/potassium transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"515.9","skeletal muscle":"882.2","tongue":"478.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"515.8","Cardiomyocytes":"158.7","Microglial cells":"141.5","Muller glia cells":"73.0","Oligodendrocyte precursor cells":"94.0","Sertoli cells":"85.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"18","RNA cancer specific FPKM":{"glioma":"91.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"51.9","HHSteC":"14.6","RH-30":"16.8","U-87 MG":"10.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022230"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022230":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.63e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-3"},"Tissue RNA - adipose tissue [nTPM]":"37.4","Tissue RNA - adrenal gland [nTPM]":"4.1","Tissue RNA - amygdala [nTPM]":"401.5","Tissue RNA - appendix [nTPM]":"1.5","Tissue RNA - basal ganglia [nTPM]":"480.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"27.4","Tissue RNA - cerebellum [nTPM]":"419.8","Tissue RNA - cerebral cortex [nTPM]":"412.8","Tissue RNA - cervix [nTPM]":"9.3","Tissue RNA - choroid plexus [nTPM]":"164.9","Tissue RNA - colon [nTPM]":"55.8","Tissue RNA - duodenum [nTPM]":"3.6","Tissue RNA - endometrium 1 [nTPM]":"5.6","Tissue RNA - epididymis [nTPM]":"12.5","Tissue RNA - esophagus [nTPM]":"33.5","Tissue RNA - fallopian tube [nTPM]":"14.5","Tissue RNA - gallbladder [nTPM]":"8.0","Tissue RNA - heart muscle [nTPM]":"144.6","Tissue RNA - hippocampal formation [nTPM]":"337.4","Tissue RNA - hypothalamus [nTPM]":"398.5","Tissue RNA - kidney [nTPM]":"3.9","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"6.4","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"429.5","Tissue RNA - midbrain [nTPM]":"478.8","Tissue RNA - ovary [nTPM]":"18.9","Tissue RNA - pancreas [nTPM]":"1.4","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"32.3","Tissue RNA - placenta [nTPM]":"3.3","Tissue RNA - pons [nTPM]":"375.3","Tissue RNA - prostate [nTPM]":"28.5","Tissue RNA - rectum [nTPM]":"8.1","Tissue RNA - retina [nTPM]":"58.5","Tissue RNA - salivary gland [nTPM]":"18.2","Tissue RNA - seminal vesicle [nTPM]":"28.5","Tissue RNA - skeletal muscle [nTPM]":"882.2","Tissue RNA - skin 1 [nTPM]":"4.7","Tissue RNA - small intestine [nTPM]":"15.9","Tissue RNA - smooth muscle [nTPM]":"7.8","Tissue RNA - spinal cord [nTPM]":"365.0","Tissue RNA - spleen [nTPM]":"1.8","Tissue RNA - stomach 1 [nTPM]":"15.7","Tissue RNA - testis [nTPM]":"5.8","Tissue RNA - thalamus [nTPM]":"515.9","Tissue RNA - thymus [nTPM]":"0.6","Tissue RNA - thyroid gland [nTPM]":"3.5","Tissue RNA - tongue [nTPM]":"478.0","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"29.9","Tissue RNA - vagina [nTPM]":"9.8","Tissue RNA - white matter [nTPM]":"327.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"51.9","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"5.9","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"14.6","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"2.7","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"4.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"16.8","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"2.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"4.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"10.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"401.5","Brain RNA - basal ganglia [nTPM]":"480.5","Brain RNA - cerebellum [nTPM]":"419.8","Brain RNA - cerebral cortex [nTPM]":"412.8","Brain RNA - hippocampal formation [nTPM]":"337.4","Brain RNA - hypothalamus [nTPM]":"398.5","Brain RNA - medulla oblongata [nTPM]":"429.5","Brain RNA - midbrain [nTPM]":"478.8","Brain RNA - pons [nTPM]":"375.3","Brain RNA - spinal cord [nTPM]":"365.0","Brain RNA - thalamus [nTPM]":"515.9","Brain RNA - white matter [nTPM]":"327.7","Single Cell Type RNA - Adipocytes [nTPM]":"1.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"515.8","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"158.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.2","Single Cell Type RNA - Endothelial cells [nTPM]":"11.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"4.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"28.9","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"141.5","Single Cell Type RNA - monocytes [nTPM]":"0.5","Single Cell Type RNA - Muller glia cells [nTPM]":"73.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"94.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"39.5","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.9","Single Cell Type RNA - Sertoli cells [nTPM]":"85.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"54.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"45.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"5.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"ATP1A3","Gene synonym":["DYT12"],"Ensembl":"ENSG00000105409","Gene description":"ATPase Na+\/K+ transporting subunit alpha 3","Uniprot":["P13637"],"Chromosome":"19","Position":"41966582-41997497","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Sodium transport","Sodium\/potassium transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Deafness","Disease variant","Dystonia","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"645.2","heart muscle":"157.7","retina":"292.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"418.1","Cone photoreceptor cells":"171.0","Horizontal cells":"213.7","Inhibitory neurons":"119.1","Late spermatids":"115.6","Rod photoreceptor cells":"291.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"21.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"57.7","JURKAT":"36.3","Karpas-707":"35.9","REH":"37.1","SCLC-21H":"128.2","SH-SY5Y":"57.7"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033630","HPA045367","HPA056446"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Approved","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"220000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB033630":"AB_781528","HPA045367":"AB_2679297","HPA056446":"AB_2683136"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.44e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.15e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.02e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"18.0","Tissue RNA - amygdala [nTPM]":"115.4","Tissue RNA - appendix [nTPM]":"1.4","Tissue RNA - basal ganglia [nTPM]":"126.3","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"76.0","Tissue RNA - cerebral cortex [nTPM]":"645.2","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"3.6","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"157.7","Tissue RNA - hippocampal formation [nTPM]":"165.8","Tissue RNA - hypothalamus [nTPM]":"275.3","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.9","Tissue RNA - medulla oblongata [nTPM]":"390.1","Tissue RNA - midbrain [nTPM]":"61.8","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"1.2","Tissue RNA - pituitary gland [nTPM]":"15.4","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"320.4","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.8","Tissue RNA - retina [nTPM]":"292.4","Tissue RNA - salivary gland [nTPM]":"0.8","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"1.5","Tissue RNA - smooth muscle [nTPM]":"0.8","Tissue RNA - spinal cord [nTPM]":"26.3","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"1.3","Tissue RNA - testis [nTPM]":"31.5","Tissue RNA - thalamus [nTPM]":"174.9","Tissue RNA - thymus [nTPM]":"2.1","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"1.8","Tissue RNA - tonsil [nTPM]":"0.6","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"200.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"2.1","Cell RNA - AF22 [nTPM]":"0.7","Cell RNA - AN3-CA [nTPM]":"23.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.6","Cell RNA - CACO-2 [nTPM]":"0.8","Cell RNA - CAPAN-2 [nTPM]":"4.3","Cell RNA - Daudi [nTPM]":"57.7","Cell RNA - EFO-21 [nTPM]":"2.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"5.6","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"16.2","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.6","Cell RNA - HDLM-2 [nTPM]":"10.7","Cell RNA - HEK 293 [nTPM]":"3.1","Cell RNA - HEL [nTPM]":"5.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"18.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"36.3","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"35.9","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"0.8","Cell RNA - MOLT-4 [nTPM]":"10.4","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"3.0","Cell RNA - OE19 [nTPM]":"8.4","Cell RNA - PC-3 [nTPM]":"14.3","Cell RNA - REH [nTPM]":"37.1","Cell RNA - RH-30 [nTPM]":"18.5","Cell RNA - RPMI-8226 [nTPM]":"1.8","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.6","Cell RNA - SCLC-21H [nTPM]":"128.2","Cell RNA - SH-SY5Y [nTPM]":"57.7","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"4.2","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"3.4","Cell RNA - THP-1 [nTPM]":"2.6","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"3.0","Cell RNA - U-2 OS [nTPM]":"3.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"1.1","Cell RNA - U-266\/70 [nTPM]":"3.7","Cell RNA - U-266\/84 [nTPM]":"2.6","Cell RNA - U-698 [nTPM]":"12.7","Cell RNA - U-87 MG [nTPM]":"5.5","Cell RNA - U-937 [nTPM]":"20.6","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"115.4","Brain RNA - basal ganglia [nTPM]":"126.3","Brain RNA - cerebellum [nTPM]":"76.0","Brain RNA - cerebral cortex [nTPM]":"645.2","Brain RNA - hippocampal formation [nTPM]":"165.8","Brain RNA - hypothalamus [nTPM]":"275.3","Brain RNA - medulla oblongata [nTPM]":"390.1","Brain RNA - midbrain [nTPM]":"61.8","Brain RNA - pons [nTPM]":"320.4","Brain RNA - spinal cord [nTPM]":"26.3","Brain RNA - thalamus [nTPM]":"174.9","Brain RNA - white matter [nTPM]":"200.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.4","Single Cell Type RNA - Astrocytes [nTPM]":"9.1","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"418.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"171.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"3.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"43.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"59.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"213.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"119.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"115.6","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"0.4","Single Cell Type RNA - Muller glia cells [nTPM]":"40.0","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"1.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"291.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"21.2","Single Cell Type RNA - Spermatogonia [nTPM]":"2.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"3.6","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"ATP6AP1","Gene synonym":["16A","Ac45","ATP6IP1","ATP6S1","CF2","ORF","VATPS1","XAP-3","XAP3"],"Ensembl":"ENSG00000071553","Gene description":"ATPase H+ transporting accessory protein 1","Uniprot":["Q15904"],"Chromosome":"X","Position":"154428633-154436516","Protein class":["Disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Hydrogen ion transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015218"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"700000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB015218":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.40e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.94e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.83e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.26e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Tissue RNA - adipose tissue [nTPM]":"56.3","Tissue RNA - adrenal gland [nTPM]":"93.5","Tissue RNA - amygdala [nTPM]":"108.3","Tissue RNA - appendix [nTPM]":"43.1","Tissue RNA - basal ganglia [nTPM]":"109.2","Tissue RNA - bone marrow [nTPM]":"59.1","Tissue RNA - breast [nTPM]":"56.7","Tissue RNA - cerebellum [nTPM]":"99.6","Tissue RNA - cerebral cortex [nTPM]":"118.0","Tissue RNA - cervix [nTPM]":"59.6","Tissue RNA - choroid plexus [nTPM]":"123.6","Tissue RNA - colon [nTPM]":"61.5","Tissue RNA - duodenum [nTPM]":"48.4","Tissue RNA - endometrium 1 [nTPM]":"54.2","Tissue RNA - epididymis [nTPM]":"145.1","Tissue RNA - esophagus [nTPM]":"85.2","Tissue RNA - fallopian tube [nTPM]":"60.0","Tissue RNA - gallbladder [nTPM]":"46.0","Tissue RNA - heart muscle [nTPM]":"92.7","Tissue RNA - hippocampal formation [nTPM]":"116.2","Tissue RNA - hypothalamus [nTPM]":"115.4","Tissue RNA - kidney [nTPM]":"104.3","Tissue RNA - liver [nTPM]":"51.4","Tissue RNA - lung [nTPM]":"96.8","Tissue RNA - lymph node [nTPM]":"46.9","Tissue RNA - medulla oblongata [nTPM]":"114.0","Tissue RNA - midbrain [nTPM]":"96.8","Tissue RNA - ovary [nTPM]":"63.3","Tissue RNA - pancreas [nTPM]":"86.6","Tissue RNA - parathyroid gland [nTPM]":"176.0","Tissue RNA - pituitary gland [nTPM]":"110.4","Tissue RNA - placenta [nTPM]":"77.9","Tissue RNA - pons [nTPM]":"121.6","Tissue RNA - prostate [nTPM]":"85.1","Tissue RNA - rectum [nTPM]":"57.0","Tissue RNA - retina [nTPM]":"74.0","Tissue RNA - salivary gland [nTPM]":"87.4","Tissue RNA - seminal vesicle [nTPM]":"54.8","Tissue RNA - skeletal muscle [nTPM]":"53.8","Tissue RNA - skin 1 [nTPM]":"83.6","Tissue RNA - small intestine [nTPM]":"57.4","Tissue RNA - smooth muscle [nTPM]":"49.0","Tissue RNA - spinal cord [nTPM]":"104.6","Tissue RNA - spleen [nTPM]":"94.7","Tissue RNA - stomach 1 [nTPM]":"70.4","Tissue RNA - testis [nTPM]":"47.5","Tissue RNA - thalamus [nTPM]":"104.2","Tissue RNA - thymus [nTPM]":"40.9","Tissue RNA - thyroid gland [nTPM]":"81.9","Tissue RNA - tongue [nTPM]":"54.4","Tissue RNA - tonsil [nTPM]":"42.5","Tissue RNA - urinary bladder [nTPM]":"63.7","Tissue RNA - vagina [nTPM]":"60.9","Tissue RNA - white matter [nTPM]":"121.6","Cell RNA - A-431 [nTPM]":"110.1","Cell RNA - A549 [nTPM]":"101.6","Cell RNA - AF22 [nTPM]":"88.2","Cell RNA - AN3-CA [nTPM]":"146.2","Cell RNA - ASC diff [nTPM]":"145.7","Cell RNA - ASC TERT1 [nTPM]":"77.4","Cell RNA - BEWO [nTPM]":"162.2","Cell RNA - BJ [nTPM]":"78.5","Cell RNA - BJ hTERT+ [nTPM]":"116.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"122.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"176.1","Cell RNA - CACO-2 [nTPM]":"93.4","Cell RNA - CAPAN-2 [nTPM]":"135.1","Cell RNA - Daudi [nTPM]":"64.7","Cell RNA - EFO-21 [nTPM]":"337.8","Cell RNA - fHDF\/TERT166 [nTPM]":"177.1","Cell RNA - GAMG [nTPM]":"216.5","Cell RNA - HaCaT [nTPM]":"112.3","Cell RNA - HAP1 [nTPM]":"133.8","Cell RNA - HBEC3-KT [nTPM]":"71.9","Cell RNA - HBF TERT88 [nTPM]":"76.6","Cell RNA - HDLM-2 [nTPM]":"58.6","Cell RNA - HEK 293 [nTPM]":"135.1","Cell RNA - HEL [nTPM]":"37.5","Cell RNA - HeLa [nTPM]":"113.7","Cell RNA - Hep G2 [nTPM]":"100.0","Cell RNA - HHSteC [nTPM]":"170.6","Cell RNA - HL-60 [nTPM]":"60.9","Cell RNA - HMC-1 [nTPM]":"260.2","Cell RNA - HSkMC [nTPM]":"98.1","Cell RNA - hTCEpi [nTPM]":"126.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"112.4","Cell RNA - hTERT-HME1 [nTPM]":"68.2","Cell RNA - hTERT-RPE1 [nTPM]":"139.5","Cell RNA - HUVEC TERT2 [nTPM]":"177.0","Cell RNA - JURKAT [nTPM]":"47.8","Cell RNA - K-562 [nTPM]":"45.6","Cell RNA - Karpas-707 [nTPM]":"176.4","Cell RNA - LHCN-M2 [nTPM]":"84.7","Cell RNA - MCF7 [nTPM]":"158.1","Cell RNA - MOLT-4 [nTPM]":"43.6","Cell RNA - NB-4 [nTPM]":"96.8","Cell RNA - NTERA-2 [nTPM]":"32.1","Cell RNA - OE19 [nTPM]":"171.0","Cell RNA - PC-3 [nTPM]":"100.8","Cell RNA - REH [nTPM]":"66.6","Cell RNA - RH-30 [nTPM]":"59.1","Cell RNA - RPMI-8226 [nTPM]":"170.7","Cell RNA - RPTEC TERT1 [nTPM]":"139.9","Cell RNA - RT4 [nTPM]":"87.3","Cell RNA - SCLC-21H [nTPM]":"84.6","Cell RNA - SH-SY5Y [nTPM]":"89.7","Cell RNA - SiHa [nTPM]":"72.6","Cell RNA - SK-BR-3 [nTPM]":"289.7","Cell RNA - SK-MEL-30 [nTPM]":"159.3","Cell RNA - SuSa [nTPM]":"87.3","Cell RNA - T-47d [nTPM]":"123.1","Cell RNA - THP-1 [nTPM]":"157.8","Cell RNA - TIME [nTPM]":"135.5","Cell RNA - U-138 MG [nTPM]":"87.4","Cell RNA - U-2 OS [nTPM]":"79.0","Cell RNA - U-2197 [nTPM]":"151.1","Cell RNA - U-251 MG [nTPM]":"135.6","Cell RNA - U-266\/70 [nTPM]":"256.3","Cell RNA - U-266\/84 [nTPM]":"311.8","Cell RNA - U-698 [nTPM]":"77.0","Cell RNA - U-87 MG [nTPM]":"104.4","Cell RNA - U-937 [nTPM]":"132.8","Cell RNA - WM-115 [nTPM]":"90.2","Blood RNA - basophil [nTPM]":"246.6","Blood RNA - classical monocyte [nTPM]":"295.1","Blood RNA - eosinophil [nTPM]":"363.9","Blood RNA - gdT-cell [nTPM]":"147.3","Blood RNA - intermediate monocyte [nTPM]":"313.8","Blood RNA - MAIT T-cell [nTPM]":"148.6","Blood RNA - memory B-cell [nTPM]":"91.7","Blood RNA - memory CD4 T-cell [nTPM]":"118.4","Blood RNA - memory CD8 T-cell [nTPM]":"127.8","Blood RNA - myeloid DC [nTPM]":"376.7","Blood RNA - naive B-cell [nTPM]":"113.6","Blood RNA - naive CD4 T-cell [nTPM]":"107.1","Blood RNA - naive CD8 T-cell [nTPM]":"117.8","Blood RNA - neutrophil [nTPM]":"326.9","Blood RNA - NK-cell [nTPM]":"140.3","Blood RNA - non-classical monocyte [nTPM]":"255.6","Blood RNA - plasmacytoid DC [nTPM]":"215.9","Blood RNA - T-reg [nTPM]":"155.2","Blood RNA - total PBMC [nTPM]":"216.9","Brain RNA - amygdala [nTPM]":"108.3","Brain RNA - basal ganglia [nTPM]":"109.2","Brain RNA - cerebellum [nTPM]":"99.6","Brain RNA - cerebral cortex [nTPM]":"118.0","Brain RNA - hippocampal formation [nTPM]":"116.2","Brain RNA - hypothalamus [nTPM]":"115.4","Brain RNA - medulla oblongata [nTPM]":"114.0","Brain RNA - midbrain [nTPM]":"96.8","Brain RNA - pons [nTPM]":"121.6","Brain RNA - spinal cord [nTPM]":"104.6","Brain RNA - thalamus [nTPM]":"104.2","Brain RNA - white matter [nTPM]":"121.6","Single Cell Type RNA - Adipocytes [nTPM]":"39.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"57.5","Single Cell Type RNA - Astrocytes [nTPM]":"17.0","Single Cell Type RNA - B-cells [nTPM]":"32.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"42.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"122.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.6","Single Cell Type RNA - Bipolar cells [nTPM]":"105.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"58.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"42.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"37.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"54.3","Single Cell Type RNA - Club cells [nTPM]":"102.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"97.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"47.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"145.1","Single Cell Type RNA - dendritic cells [nTPM]":"40.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"84.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"65.4","Single Cell Type RNA - Early spermatids [nTPM]":"3.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"52.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"33.7","Single Cell Type RNA - Endothelial cells [nTPM]":"50.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"89.0","Single Cell Type RNA - Erythroid cells [nTPM]":"35.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"52.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"104.5","Single Cell Type RNA - Fibroblasts [nTPM]":"48.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"36.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"57.4","Single Cell Type RNA - granulocytes [nTPM]":"77.3","Single Cell Type RNA - Granulosa cells [nTPM]":"51.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"54.3","Single Cell Type RNA - Hepatocytes [nTPM]":"46.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"246.3","Single Cell Type RNA - Horizontal cells [nTPM]":"129.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"59.0","Single Cell Type RNA - Ionocytes [nTPM]":"160.7","Single Cell Type RNA - Kupffer cells [nTPM]":"143.6","Single Cell Type RNA - Langerhans cells [nTPM]":"88.2","Single Cell Type RNA - Late spermatids [nTPM]":"5.5","Single Cell Type RNA - Leydig cells [nTPM]":"41.3","Single Cell Type RNA - Macrophages [nTPM]":"130.3","Single Cell Type RNA - Melanocytes [nTPM]":"72.9","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"79.9","Single Cell Type RNA - Muller glia cells [nTPM]":"68.4","Single Cell Type RNA - NK-cells [nTPM]":"27.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"22.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"26.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"42.4","Single Cell Type RNA - Paneth cells [nTPM]":"67.5","Single Cell Type RNA - Peritubular cells [nTPM]":"42.5","Single Cell Type RNA - Plasma cells [nTPM]":"61.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"34.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"63.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"49.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"112.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"69.2","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"35.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"45.5","Single Cell Type RNA - Spermatocytes [nTPM]":"64.4","Single Cell Type RNA - Spermatogonia [nTPM]":"10.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"31.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"32.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"196.5","Single Cell Type RNA - T-cells [nTPM]":"36.3","Single Cell Type RNA - Theca cells [nTPM]":"74.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"54.6","Single Cell Type RNA - Urothelial cells [nTPM]":"47.2"},{"Gene":"ATP6AP2","Gene synonym":["APT6M8-9","ATP6IP2","ATP6M8-9","M8-9","PRR","RENR"],"Ensembl":"ENSG00000182220","Gene description":"ATPase H+ transporting accessory protein 2","Uniprot":["O75787"],"Chromosome":"X","Position":"40579372-40606848","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant","Epilepsy","Mental retardation","Neurodegeneration","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"parathyroid gland":"765.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"702.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003156"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"140000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA003156":"AB_1078245"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.01e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Tissue RNA - adipose tissue [nTPM]":"81.2","Tissue RNA - adrenal gland [nTPM]":"71.5","Tissue RNA - amygdala [nTPM]":"85.6","Tissue RNA - appendix [nTPM]":"60.6","Tissue RNA - basal ganglia [nTPM]":"86.5","Tissue RNA - bone marrow [nTPM]":"124.4","Tissue RNA - breast [nTPM]":"95.1","Tissue RNA - cerebellum [nTPM]":"76.4","Tissue RNA - cerebral cortex [nTPM]":"116.9","Tissue RNA - cervix [nTPM]":"106.1","Tissue RNA - choroid plexus [nTPM]":"72.4","Tissue RNA - colon [nTPM]":"82.9","Tissue RNA - duodenum [nTPM]":"32.1","Tissue RNA - endometrium 1 [nTPM]":"86.6","Tissue RNA - epididymis [nTPM]":"91.3","Tissue RNA - esophagus [nTPM]":"70.1","Tissue RNA - fallopian tube [nTPM]":"75.6","Tissue RNA - gallbladder [nTPM]":"79.7","Tissue RNA - heart muscle [nTPM]":"55.1","Tissue RNA - hippocampal formation [nTPM]":"90.8","Tissue RNA - hypothalamus [nTPM]":"90.2","Tissue RNA - kidney [nTPM]":"165.6","Tissue RNA - liver [nTPM]":"96.8","Tissue RNA - lung [nTPM]":"87.3","Tissue RNA - lymph node [nTPM]":"67.4","Tissue RNA - medulla oblongata [nTPM]":"80.4","Tissue RNA - midbrain [nTPM]":"79.8","Tissue RNA - ovary [nTPM]":"68.9","Tissue RNA - pancreas [nTPM]":"53.3","Tissue RNA - parathyroid gland [nTPM]":"765.1","Tissue RNA - pituitary gland [nTPM]":"30.7","Tissue RNA - placenta [nTPM]":"106.9","Tissue RNA - pons [nTPM]":"83.4","Tissue RNA - prostate [nTPM]":"86.6","Tissue RNA - rectum [nTPM]":"89.0","Tissue RNA - retina [nTPM]":"99.3","Tissue RNA - salivary gland [nTPM]":"39.4","Tissue RNA - seminal vesicle [nTPM]":"97.9","Tissue RNA - skeletal muscle [nTPM]":"18.4","Tissue RNA - skin 1 [nTPM]":"71.9","Tissue RNA - small intestine [nTPM]":"47.8","Tissue RNA - smooth muscle [nTPM]":"124.7","Tissue RNA - spinal cord [nTPM]":"84.6","Tissue RNA - spleen [nTPM]":"69.0","Tissue RNA - stomach 1 [nTPM]":"49.1","Tissue RNA - testis [nTPM]":"40.4","Tissue RNA - thalamus [nTPM]":"87.6","Tissue RNA - thymus [nTPM]":"72.0","Tissue RNA - thyroid gland [nTPM]":"177.1","Tissue RNA - tongue [nTPM]":"40.1","Tissue RNA - tonsil [nTPM]":"72.5","Tissue RNA - urinary bladder [nTPM]":"97.7","Tissue RNA - vagina [nTPM]":"41.4","Tissue RNA - white matter [nTPM]":"98.7","Cell RNA - A-431 [nTPM]":"83.9","Cell RNA - A549 [nTPM]":"117.5","Cell RNA - AF22 [nTPM]":"78.7","Cell RNA - AN3-CA [nTPM]":"106.7","Cell RNA - ASC diff [nTPM]":"472.6","Cell RNA - ASC TERT1 [nTPM]":"312.4","Cell RNA - BEWO [nTPM]":"47.9","Cell RNA - BJ [nTPM]":"182.4","Cell RNA - BJ hTERT+ [nTPM]":"274.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"127.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"152.9","Cell RNA - CACO-2 [nTPM]":"68.0","Cell RNA - CAPAN-2 [nTPM]":"142.6","Cell RNA - Daudi [nTPM]":"48.4","Cell RNA - EFO-21 [nTPM]":"88.1","Cell RNA - fHDF\/TERT166 [nTPM]":"257.0","Cell RNA - GAMG [nTPM]":"141.3","Cell RNA - HaCaT [nTPM]":"86.6","Cell RNA - HAP1 [nTPM]":"114.0","Cell RNA - HBEC3-KT [nTPM]":"136.0","Cell RNA - HBF TERT88 [nTPM]":"168.2","Cell RNA - HDLM-2 [nTPM]":"92.7","Cell RNA - HEK 293 [nTPM]":"97.7","Cell RNA - HEL [nTPM]":"57.5","Cell RNA - HeLa [nTPM]":"100.2","Cell RNA - Hep G2 [nTPM]":"66.5","Cell RNA - HHSteC [nTPM]":"172.0","Cell RNA - HL-60 [nTPM]":"104.6","Cell RNA - HMC-1 [nTPM]":"111.6","Cell RNA - HSkMC [nTPM]":"259.6","Cell RNA - hTCEpi [nTPM]":"175.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"154.2","Cell RNA - hTERT-HME1 [nTPM]":"121.4","Cell RNA - hTERT-RPE1 [nTPM]":"200.3","Cell RNA - HUVEC TERT2 [nTPM]":"168.1","Cell RNA - JURKAT [nTPM]":"46.1","Cell RNA - K-562 [nTPM]":"63.8","Cell RNA - Karpas-707 [nTPM]":"130.7","Cell RNA - LHCN-M2 [nTPM]":"201.7","Cell RNA - MCF7 [nTPM]":"109.8","Cell RNA - MOLT-4 [nTPM]":"45.5","Cell RNA - NB-4 [nTPM]":"93.7","Cell RNA - NTERA-2 [nTPM]":"73.4","Cell RNA - OE19 [nTPM]":"140.8","Cell RNA - PC-3 [nTPM]":"112.7","Cell RNA - REH [nTPM]":"43.8","Cell RNA - RH-30 [nTPM]":"132.6","Cell RNA - RPMI-8226 [nTPM]":"161.6","Cell RNA - RPTEC TERT1 [nTPM]":"182.8","Cell RNA - RT4 [nTPM]":"96.8","Cell RNA - SCLC-21H [nTPM]":"55.2","Cell RNA - SH-SY5Y [nTPM]":"51.9","Cell RNA - SiHa [nTPM]":"185.8","Cell RNA - SK-BR-3 [nTPM]":"111.7","Cell RNA - SK-MEL-30 [nTPM]":"118.4","Cell RNA - SuSa [nTPM]":"284.2","Cell RNA - T-47d [nTPM]":"147.8","Cell RNA - THP-1 [nTPM]":"97.1","Cell RNA - TIME [nTPM]":"172.5","Cell RNA - U-138 MG [nTPM]":"175.0","Cell RNA - U-2 OS [nTPM]":"91.3","Cell RNA - U-2197 [nTPM]":"207.7","Cell RNA - U-251 MG [nTPM]":"62.8","Cell RNA - U-266\/70 [nTPM]":"38.0","Cell RNA - U-266\/84 [nTPM]":"70.7","Cell RNA - U-698 [nTPM]":"46.2","Cell RNA - U-87 MG [nTPM]":"139.1","Cell RNA - U-937 [nTPM]":"93.0","Cell RNA - WM-115 [nTPM]":"138.5","Blood RNA - basophil [nTPM]":"269.0","Blood RNA - classical monocyte [nTPM]":"511.1","Blood RNA - eosinophil [nTPM]":"404.8","Blood RNA - gdT-cell [nTPM]":"156.1","Blood RNA - intermediate monocyte [nTPM]":"364.9","Blood RNA - MAIT T-cell [nTPM]":"164.3","Blood RNA - memory B-cell [nTPM]":"106.7","Blood RNA - memory CD4 T-cell [nTPM]":"157.3","Blood RNA - memory CD8 T-cell [nTPM]":"161.9","Blood RNA - myeloid DC [nTPM]":"341.3","Blood RNA - naive B-cell [nTPM]":"110.3","Blood RNA - naive CD4 T-cell [nTPM]":"174.8","Blood RNA - naive CD8 T-cell [nTPM]":"159.3","Blood RNA - neutrophil [nTPM]":"255.9","Blood RNA - NK-cell [nTPM]":"141.2","Blood RNA - non-classical monocyte [nTPM]":"378.6","Blood RNA - plasmacytoid DC [nTPM]":"124.2","Blood RNA - T-reg [nTPM]":"167.2","Blood RNA - total PBMC [nTPM]":"692.9","Brain RNA - amygdala [nTPM]":"85.6","Brain RNA - basal ganglia [nTPM]":"86.5","Brain RNA - cerebellum [nTPM]":"76.4","Brain RNA - cerebral cortex [nTPM]":"116.9","Brain RNA - hippocampal formation [nTPM]":"90.8","Brain RNA - hypothalamus [nTPM]":"90.2","Brain RNA - medulla oblongata [nTPM]":"80.4","Brain RNA - midbrain [nTPM]":"79.8","Brain RNA - pons [nTPM]":"83.4","Brain RNA - spinal cord [nTPM]":"84.6","Brain RNA - thalamus [nTPM]":"87.6","Brain RNA - white matter [nTPM]":"98.7","Single Cell Type RNA - Adipocytes [nTPM]":"102.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"57.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"65.6","Single Cell Type RNA - Astrocytes [nTPM]":"36.2","Single Cell Type RNA - B-cells [nTPM]":"65.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"97.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"135.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"254.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"46.1","Single Cell Type RNA - Bipolar cells [nTPM]":"155.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"74.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"61.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"30.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"94.4","Single Cell Type RNA - Club cells [nTPM]":"175.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"138.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"54.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"173.4","Single Cell Type RNA - dendritic cells [nTPM]":"109.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"70.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"62.6","Single Cell Type RNA - Ductal cells [nTPM]":"146.6","Single Cell Type RNA - Early spermatids [nTPM]":"3.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"97.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"115.5","Single Cell Type RNA - Endothelial cells [nTPM]":"94.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"57.1","Single Cell Type RNA - Erythroid cells [nTPM]":"62.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"44.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"59.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"106.3","Single Cell Type RNA - Fibroblasts [nTPM]":"156.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"34.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"124.5","Single Cell Type RNA - granulocytes [nTPM]":"87.5","Single Cell Type RNA - Granulosa cells [nTPM]":"63.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"96.0","Single Cell Type RNA - Hepatocytes [nTPM]":"64.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"702.2","Single Cell Type RNA - Horizontal cells [nTPM]":"188.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"56.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"54.6","Single Cell Type RNA - Ionocytes [nTPM]":"349.9","Single Cell Type RNA - Kupffer cells [nTPM]":"279.5","Single Cell Type RNA - Langerhans cells [nTPM]":"263.3","Single Cell Type RNA - Late spermatids [nTPM]":"9.5","Single Cell Type RNA - Leydig cells [nTPM]":"117.4","Single Cell Type RNA - Macrophages [nTPM]":"222.0","Single Cell Type RNA - Melanocytes [nTPM]":"149.4","Single Cell Type RNA - Microglial cells [nTPM]":"28.1","Single Cell Type RNA - monocytes [nTPM]":"185.4","Single Cell Type RNA - Muller glia cells [nTPM]":"193.0","Single Cell Type RNA - NK-cells [nTPM]":"72.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"40.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"40.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"64.0","Single Cell Type RNA - Paneth cells [nTPM]":"58.9","Single Cell Type RNA - Peritubular cells [nTPM]":"151.2","Single Cell Type RNA - Plasma cells [nTPM]":"74.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"97.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"61.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"106.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"127.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"93.3","Single Cell Type RNA - Sertoli cells [nTPM]":"105.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"116.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"138.7","Single Cell Type RNA - Spermatocytes [nTPM]":"106.7","Single Cell Type RNA - Spermatogonia [nTPM]":"43.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"60.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"99.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"174.4","Single Cell Type RNA - T-cells [nTPM]":"100.3","Single Cell Type RNA - Theca cells [nTPM]":"188.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"63.6","Single Cell Type RNA - Urothelial cells [nTPM]":"121.1"},{"Gene":"ATP6V0A4","Gene synonym":["a4","ATP6N1B","ATP6N2","RDRTA2","RTA1C","RTADR","Stv1","Vph1","VPP2"],"Ensembl":"ENSG00000105929","Gene description":"ATPase H+ transporting V0 subunit a4","Uniprot":["Q9HBG4"],"Chromosome":"7","Position":"138706294-138799560","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Hydrogen ion transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"kidney":"63.6","salivary gland":"78.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"16.5","Cytotrophoblasts":"13.4","Distal tubular cells":"31.3","Ionocytes":"57.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"renal cancer":"25.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"SK-BR-3":"55.7"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018029","HPA064555"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA018029":"AB_1845190","HPA064555":"AB_2685284"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.32e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"4.7","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"3.7","Tissue RNA - choroid plexus [nTPM]":"3.1","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"1.2","Tissue RNA - esophagus [nTPM]":"4.9","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.6","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"63.6","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"1.6","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"2.5","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.9","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"78.4","Tissue RNA - seminal vesicle [nTPM]":"1.5","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"10.2","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"3.7","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.5","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"0.8","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.6","Cell RNA - CACO-2 [nTPM]":"1.8","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.7","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.6","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.7","Cell RNA - MCF7 [nTPM]":"5.0","Cell RNA - MOLT-4 [nTPM]":"1.9","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.6","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"4.5","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"55.7","Cell RNA - SK-MEL-30 [nTPM]":"1.9","Cell RNA - SuSa [nTPM]":"2.9","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.6","Cell RNA - U-2 OS [nTPM]":"1.3","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"0.6","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"31.3","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"57.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.1","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"ATP6V1B1","Gene synonym":["ATP6B1","RTA1B","VATB","Vma2","VPP3"],"Ensembl":"ENSG00000116039","Gene description":"ATPase H+ transporting V1 subunit B1","Uniprot":["P15313"],"Chromosome":"2","Position":"70935900-70965431","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Hydrogen ion transport","Ion transport","Transport"],"Molecular function":["Hydrolase"],"Disease involvement":["Deafness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"kidney":"127.4","salivary gland":"139.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"197.3","Distal tubular cells":"49.0","Ionocytes":"321.4","Syncytiotrophoblasts":"64.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"ovarian cancer":"94.7","renal cancer":"23.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"BEWO":"21.6","HaCaT":"20.3","SK-BR-3":"49.2"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009523","HPA031847"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Nucleoplasm","Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB009523":"AB_677577","HPA031847":"AB_2674072"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.2","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"11.8","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"0.9","Tissue RNA - cervix [nTPM]":"31.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.6","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"1.4","Tissue RNA - epididymis [nTPM]":"1.2","Tissue RNA - esophagus [nTPM]":"1.6","Tissue RNA - fallopian tube [nTPM]":"12.8","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"1.1","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"127.4","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"1.7","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"1.2","Tissue RNA - pancreas [nTPM]":"3.3","Tissue RNA - parathyroid gland [nTPM]":"0.8","Tissue RNA - pituitary gland [nTPM]":"4.2","Tissue RNA - placenta [nTPM]":"17.9","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"2.0","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"3.9","Tissue RNA - salivary gland [nTPM]":"139.8","Tissue RNA - seminal vesicle [nTPM]":"1.4","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"32.5","Tissue RNA - small intestine [nTPM]":"0.6","Tissue RNA - smooth muscle [nTPM]":"0.8","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.6","Tissue RNA - vagina [nTPM]":"0.8","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"1.3","Cell RNA - ASC diff [nTPM]":"2.6","Cell RNA - ASC TERT1 [nTPM]":"3.1","Cell RNA - BEWO [nTPM]":"21.6","Cell RNA - BJ [nTPM]":"0.4","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"2.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"1.2","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"20.3","Cell RNA - HAP1 [nTPM]":"0.7","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.5","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"1.5","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"3.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"1.2","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.8","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.4","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"1.5","Cell RNA - SiHa [nTPM]":"0.7","Cell RNA - SK-BR-3 [nTPM]":"49.2","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"2.7","Cell RNA - T-47d [nTPM]":"0.6","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.6","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.9","Cell RNA - U-251 MG [nTPM]":"0.5","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"0.9","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"13.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"197.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"49.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"38.3","Single Cell Type RNA - Fibroblasts [nTPM]":"3.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.7","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"321.4","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"64.9","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"ATP6V1E1","Gene synonym":["ATP6E","ATP6E2","ATP6V1E","P31","Vma4"],"Ensembl":"ENSG00000131100","Gene description":"ATPase H+ transporting V1 subunit E1","Uniprot":["P36543"],"Chromosome":"22","Position":"17592136-17628749","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Hydrogen ion transport","Ion transport","Transport"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"461.8","Proximal tubular cells":"411.3","Syncytiotrophoblasts":"479.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009528","CAB018699","HPA029196"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"34000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB009528":"AB_2062678","CAB018699":"AB_781534","HPA029196":"AB_2672944"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.56e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.72e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.18e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.66e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Tissue RNA - adipose tissue [nTPM]":"119.5","Tissue RNA - adrenal gland [nTPM]":"165.0","Tissue RNA - amygdala [nTPM]":"209.8","Tissue RNA - appendix [nTPM]":"68.3","Tissue RNA - basal ganglia [nTPM]":"220.9","Tissue RNA - bone marrow [nTPM]":"90.4","Tissue RNA - breast [nTPM]":"109.5","Tissue RNA - cerebellum [nTPM]":"214.3","Tissue RNA - cerebral cortex [nTPM]":"287.3","Tissue RNA - cervix [nTPM]":"101.7","Tissue RNA - choroid plexus [nTPM]":"200.4","Tissue RNA - colon [nTPM]":"128.9","Tissue RNA - duodenum [nTPM]":"56.6","Tissue RNA - endometrium 1 [nTPM]":"112.2","Tissue RNA - epididymis [nTPM]":"135.8","Tissue RNA - esophagus [nTPM]":"117.2","Tissue RNA - fallopian tube [nTPM]":"96.0","Tissue RNA - gallbladder [nTPM]":"84.7","Tissue RNA - heart muscle [nTPM]":"224.9","Tissue RNA - hippocampal formation [nTPM]":"231.8","Tissue RNA - hypothalamus [nTPM]":"226.9","Tissue RNA - kidney [nTPM]":"230.5","Tissue RNA - liver [nTPM]":"85.6","Tissue RNA - lung [nTPM]":"110.3","Tissue RNA - lymph node [nTPM]":"88.6","Tissue RNA - medulla oblongata [nTPM]":"220.3","Tissue RNA - midbrain [nTPM]":"202.3","Tissue RNA - ovary [nTPM]":"81.9","Tissue RNA - pancreas [nTPM]":"59.5","Tissue RNA - parathyroid gland [nTPM]":"239.9","Tissue RNA - pituitary gland [nTPM]":"117.1","Tissue RNA - placenta [nTPM]":"113.8","Tissue RNA - pons [nTPM]":"230.8","Tissue RNA - prostate [nTPM]":"95.0","Tissue RNA - rectum [nTPM]":"99.7","Tissue RNA - retina [nTPM]":"128.4","Tissue RNA - salivary gland [nTPM]":"83.7","Tissue RNA - seminal vesicle [nTPM]":"126.4","Tissue RNA - skeletal muscle [nTPM]":"232.8","Tissue RNA - skin 1 [nTPM]":"120.3","Tissue RNA - small intestine [nTPM]":"83.1","Tissue RNA - smooth muscle [nTPM]":"121.0","Tissue RNA - spinal cord [nTPM]":"215.9","Tissue RNA - spleen [nTPM]":"99.0","Tissue RNA - stomach 1 [nTPM]":"101.8","Tissue RNA - testis [nTPM]":"67.3","Tissue RNA - thalamus [nTPM]":"218.1","Tissue RNA - thymus [nTPM]":"108.2","Tissue RNA - thyroid gland [nTPM]":"100.8","Tissue RNA - tongue [nTPM]":"178.6","Tissue RNA - tonsil [nTPM]":"109.5","Tissue RNA - urinary bladder [nTPM]":"114.5","Tissue RNA - vagina [nTPM]":"97.6","Tissue RNA - white matter [nTPM]":"245.6","Cell RNA - A-431 [nTPM]":"121.8","Cell RNA - A549 [nTPM]":"108.6","Cell RNA - AF22 [nTPM]":"96.4","Cell RNA - AN3-CA [nTPM]":"94.3","Cell RNA - ASC diff [nTPM]":"314.4","Cell RNA - ASC TERT1 [nTPM]":"169.6","Cell RNA - BEWO [nTPM]":"106.0","Cell RNA - BJ [nTPM]":"159.3","Cell RNA - BJ hTERT+ [nTPM]":"212.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"198.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"228.0","Cell RNA - CACO-2 [nTPM]":"137.3","Cell RNA - CAPAN-2 [nTPM]":"97.5","Cell RNA - Daudi [nTPM]":"76.1","Cell RNA - EFO-21 [nTPM]":"132.8","Cell RNA - fHDF\/TERT166 [nTPM]":"215.0","Cell RNA - GAMG [nTPM]":"251.8","Cell RNA - HaCaT [nTPM]":"187.9","Cell RNA - HAP1 [nTPM]":"152.8","Cell RNA - HBEC3-KT [nTPM]":"140.2","Cell RNA - HBF TERT88 [nTPM]":"174.9","Cell RNA - HDLM-2 [nTPM]":"145.9","Cell RNA - HEK 293 [nTPM]":"173.3","Cell RNA - HEL [nTPM]":"137.1","Cell RNA - HeLa [nTPM]":"97.5","Cell RNA - Hep G2 [nTPM]":"182.7","Cell RNA - HHSteC [nTPM]":"459.9","Cell RNA - HL-60 [nTPM]":"159.8","Cell RNA - HMC-1 [nTPM]":"226.5","Cell RNA - HSkMC [nTPM]":"212.9","Cell RNA - hTCEpi [nTPM]":"267.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"192.4","Cell RNA - hTERT-HME1 [nTPM]":"138.7","Cell RNA - hTERT-RPE1 [nTPM]":"220.9","Cell RNA - HUVEC TERT2 [nTPM]":"170.2","Cell RNA - JURKAT [nTPM]":"95.0","Cell RNA - K-562 [nTPM]":"174.8","Cell RNA - Karpas-707 [nTPM]":"150.3","Cell RNA - LHCN-M2 [nTPM]":"341.9","Cell RNA - MCF7 [nTPM]":"127.4","Cell RNA - MOLT-4 [nTPM]":"136.5","Cell RNA - NB-4 [nTPM]":"114.5","Cell RNA - NTERA-2 [nTPM]":"71.0","Cell RNA - OE19 [nTPM]":"269.6","Cell RNA - PC-3 [nTPM]":"152.6","Cell RNA - REH [nTPM]":"80.3","Cell RNA - RH-30 [nTPM]":"140.7","Cell RNA - RPMI-8226 [nTPM]":"45.7","Cell RNA - RPTEC TERT1 [nTPM]":"331.6","Cell RNA - RT4 [nTPM]":"189.0","Cell RNA - SCLC-21H [nTPM]":"70.3","Cell RNA - SH-SY5Y [nTPM]":"122.7","Cell RNA - SiHa [nTPM]":"146.0","Cell RNA - SK-BR-3 [nTPM]":"101.0","Cell RNA - SK-MEL-30 [nTPM]":"358.9","Cell RNA - SuSa [nTPM]":"187.0","Cell RNA - T-47d [nTPM]":"98.6","Cell RNA - THP-1 [nTPM]":"180.4","Cell RNA - TIME [nTPM]":"146.3","Cell RNA - U-138 MG [nTPM]":"137.5","Cell RNA - U-2 OS [nTPM]":"72.6","Cell RNA - U-2197 [nTPM]":"174.0","Cell RNA - U-251 MG [nTPM]":"119.2","Cell RNA - U-266\/70 [nTPM]":"145.7","Cell RNA - U-266\/84 [nTPM]":"275.5","Cell RNA - U-698 [nTPM]":"96.3","Cell RNA - U-87 MG [nTPM]":"221.2","Cell RNA - U-937 [nTPM]":"76.7","Cell RNA - WM-115 [nTPM]":"189.3","Blood RNA - basophil [nTPM]":"178.1","Blood RNA - classical monocyte [nTPM]":"106.3","Blood RNA - eosinophil [nTPM]":"184.7","Blood RNA - gdT-cell [nTPM]":"64.0","Blood RNA - intermediate monocyte [nTPM]":"100.9","Blood RNA - MAIT T-cell [nTPM]":"63.0","Blood RNA - memory B-cell [nTPM]":"78.7","Blood RNA - memory CD4 T-cell [nTPM]":"64.7","Blood RNA - memory CD8 T-cell [nTPM]":"61.5","Blood RNA - myeloid DC [nTPM]":"83.6","Blood RNA - naive B-cell [nTPM]":"59.8","Blood RNA - naive CD4 T-cell [nTPM]":"60.8","Blood RNA - naive CD8 T-cell [nTPM]":"63.7","Blood RNA - neutrophil [nTPM]":"137.6","Blood RNA - NK-cell [nTPM]":"76.0","Blood RNA - non-classical monocyte [nTPM]":"120.5","Blood RNA - plasmacytoid DC [nTPM]":"81.2","Blood RNA - T-reg [nTPM]":"97.7","Blood RNA - total PBMC [nTPM]":"112.8","Brain RNA - amygdala [nTPM]":"209.8","Brain RNA - basal ganglia [nTPM]":"220.9","Brain RNA - cerebellum [nTPM]":"214.3","Brain RNA - cerebral cortex [nTPM]":"287.3","Brain RNA - hippocampal formation [nTPM]":"231.8","Brain RNA - hypothalamus [nTPM]":"226.9","Brain RNA - medulla oblongata [nTPM]":"220.3","Brain RNA - midbrain [nTPM]":"202.3","Brain RNA - pons [nTPM]":"230.8","Brain RNA - spinal cord [nTPM]":"215.9","Brain RNA - thalamus [nTPM]":"218.1","Brain RNA - white matter [nTPM]":"245.6","Single Cell Type RNA - Adipocytes [nTPM]":"66.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"76.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"83.4","Single Cell Type RNA - Astrocytes [nTPM]":"13.4","Single Cell Type RNA - B-cells [nTPM]":"47.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"41.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"77.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"121.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.9","Single Cell Type RNA - Bipolar cells [nTPM]":"54.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"33.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"34.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"126.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"74.4","Single Cell Type RNA - Club cells [nTPM]":"83.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"138.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"235.1","Single Cell Type RNA - dendritic cells [nTPM]":"63.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"105.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"461.8","Single Cell Type RNA - Ductal cells [nTPM]":"143.8","Single Cell Type RNA - Early spermatids [nTPM]":"7.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"74.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"56.9","Single Cell Type RNA - Endothelial cells [nTPM]":"69.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"41.9","Single Cell Type RNA - Erythroid cells [nTPM]":"49.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"24.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"119.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"143.9","Single Cell Type RNA - Fibroblasts [nTPM]":"60.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"40.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"79.2","Single Cell Type RNA - granulocytes [nTPM]":"90.5","Single Cell Type RNA - Granulosa cells [nTPM]":"41.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"72.5","Single Cell Type RNA - Hepatocytes [nTPM]":"46.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"186.8","Single Cell Type RNA - Horizontal cells [nTPM]":"53.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"54.0","Single Cell Type RNA - Ionocytes [nTPM]":"116.0","Single Cell Type RNA - Kupffer cells [nTPM]":"75.1","Single Cell Type RNA - Langerhans cells [nTPM]":"52.1","Single Cell Type RNA - Late spermatids [nTPM]":"17.9","Single Cell Type RNA - Leydig cells [nTPM]":"94.1","Single Cell Type RNA - Macrophages [nTPM]":"91.9","Single Cell Type RNA - Melanocytes [nTPM]":"80.0","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"144.1","Single Cell Type RNA - Muller glia cells [nTPM]":"94.1","Single Cell Type RNA - NK-cells [nTPM]":"85.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"31.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"154.7","Single Cell Type RNA - Paneth cells [nTPM]":"104.7","Single Cell Type RNA - Peritubular cells [nTPM]":"97.8","Single Cell Type RNA - Plasma cells [nTPM]":"38.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"60.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"65.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"411.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"78.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"50.4","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"39.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"74.5","Single Cell Type RNA - Spermatocytes [nTPM]":"71.7","Single Cell Type RNA - Spermatogonia [nTPM]":"74.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"34.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"51.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"479.1","Single Cell Type RNA - T-cells [nTPM]":"54.6","Single Cell Type RNA - Theca cells [nTPM]":"57.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"40.1","Single Cell Type RNA - Urothelial cells [nTPM]":"93.1"},{"Gene":"ATP7A","Gene synonym":["MNK"],"Ensembl":"ENSG00000165240","Gene description":"ATPase copper transporting alpha","Uniprot":["Q04656"],"Chromosome":"X","Position":"77910656-78050395","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Copper transport","Ion transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ionocytes":"61.1","Microglial cells":"44.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012887","HPA048107"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA012887":"AB_1845205","HPA048107":"AB_2680266"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.38e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.0","Tissue RNA - adrenal gland [nTPM]":"4.3","Tissue RNA - amygdala [nTPM]":"1.2","Tissue RNA - appendix [nTPM]":"3.6","Tissue RNA - basal ganglia [nTPM]":"1.7","Tissue RNA - bone marrow [nTPM]":"5.9","Tissue RNA - breast [nTPM]":"6.3","Tissue RNA - cerebellum [nTPM]":"2.3","Tissue RNA - cerebral cortex [nTPM]":"2.1","Tissue RNA - cervix [nTPM]":"3.9","Tissue RNA - choroid plexus [nTPM]":"1.6","Tissue RNA - colon [nTPM]":"3.4","Tissue RNA - duodenum [nTPM]":"3.9","Tissue RNA - endometrium 1 [nTPM]":"3.6","Tissue RNA - epididymis [nTPM]":"5.0","Tissue RNA - esophagus [nTPM]":"4.9","Tissue RNA - fallopian tube [nTPM]":"3.5","Tissue RNA - gallbladder [nTPM]":"3.6","Tissue RNA - heart muscle [nTPM]":"2.5","Tissue RNA - hippocampal formation [nTPM]":"1.3","Tissue RNA - hypothalamus [nTPM]":"2.1","Tissue RNA - kidney [nTPM]":"4.4","Tissue RNA - liver [nTPM]":"2.3","Tissue RNA - lung [nTPM]":"4.5","Tissue RNA - lymph node [nTPM]":"4.1","Tissue RNA - medulla oblongata [nTPM]":"2.1","Tissue RNA - midbrain [nTPM]":"2.1","Tissue RNA - ovary [nTPM]":"3.6","Tissue RNA - pancreas [nTPM]":"2.4","Tissue RNA - parathyroid gland [nTPM]":"7.3","Tissue RNA - pituitary gland [nTPM]":"2.5","Tissue RNA - placenta [nTPM]":"4.0","Tissue RNA - pons [nTPM]":"3.8","Tissue RNA - prostate [nTPM]":"5.3","Tissue RNA - rectum [nTPM]":"3.4","Tissue RNA - retina [nTPM]":"3.0","Tissue RNA - salivary gland [nTPM]":"5.1","Tissue RNA - seminal vesicle [nTPM]":"3.4","Tissue RNA - skeletal muscle [nTPM]":"1.8","Tissue RNA - skin 1 [nTPM]":"11.1","Tissue RNA - small intestine [nTPM]":"3.4","Tissue RNA - smooth muscle [nTPM]":"3.2","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"4.7","Tissue RNA - stomach 1 [nTPM]":"5.5","Tissue RNA - testis [nTPM]":"1.6","Tissue RNA - thalamus [nTPM]":"1.6","Tissue RNA - thymus [nTPM]":"4.7","Tissue RNA - thyroid gland [nTPM]":"4.6","Tissue RNA - tongue [nTPM]":"2.9","Tissue RNA - tonsil [nTPM]":"4.6","Tissue RNA - urinary bladder [nTPM]":"3.9","Tissue RNA - vagina [nTPM]":"2.8","Tissue RNA - white matter [nTPM]":"2.9","Cell RNA - A-431 [nTPM]":"3.2","Cell RNA - A549 [nTPM]":"8.3","Cell RNA - AF22 [nTPM]":"5.4","Cell RNA - AN3-CA [nTPM]":"5.5","Cell RNA - ASC diff [nTPM]":"5.0","Cell RNA - ASC TERT1 [nTPM]":"5.3","Cell RNA - BEWO [nTPM]":"0.9","Cell RNA - BJ [nTPM]":"4.8","Cell RNA - BJ hTERT+ [nTPM]":"6.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.7","Cell RNA - CACO-2 [nTPM]":"1.0","Cell RNA - CAPAN-2 [nTPM]":"3.6","Cell RNA - Daudi [nTPM]":"4.7","Cell RNA - EFO-21 [nTPM]":"6.9","Cell RNA - fHDF\/TERT166 [nTPM]":"4.8","Cell RNA - GAMG [nTPM]":"3.3","Cell RNA - HaCaT [nTPM]":"3.8","Cell RNA - HAP1 [nTPM]":"7.1","Cell RNA - HBEC3-KT [nTPM]":"3.9","Cell RNA - HBF TERT88 [nTPM]":"5.2","Cell RNA - HDLM-2 [nTPM]":"7.0","Cell RNA - HEK 293 [nTPM]":"4.8","Cell RNA - HEL [nTPM]":"2.4","Cell RNA - HeLa [nTPM]":"7.8","Cell RNA - Hep G2 [nTPM]":"0.8","Cell RNA - HHSteC [nTPM]":"6.3","Cell RNA - HL-60 [nTPM]":"4.1","Cell RNA - HMC-1 [nTPM]":"4.1","Cell RNA - HSkMC [nTPM]":"5.6","Cell RNA - hTCEpi [nTPM]":"1.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.9","Cell RNA - hTERT-HME1 [nTPM]":"1.8","Cell RNA - hTERT-RPE1 [nTPM]":"6.5","Cell RNA - HUVEC TERT2 [nTPM]":"7.3","Cell RNA - JURKAT [nTPM]":"4.7","Cell RNA - K-562 [nTPM]":"19.6","Cell RNA - Karpas-707 [nTPM]":"17.4","Cell RNA - LHCN-M2 [nTPM]":"5.2","Cell RNA - MCF7 [nTPM]":"2.8","Cell RNA - MOLT-4 [nTPM]":"4.6","Cell RNA - NB-4 [nTPM]":"1.4","Cell RNA - NTERA-2 [nTPM]":"1.5","Cell RNA - OE19 [nTPM]":"11.2","Cell RNA - PC-3 [nTPM]":"1.7","Cell RNA - REH [nTPM]":"3.7","Cell RNA - RH-30 [nTPM]":"9.0","Cell RNA - RPMI-8226 [nTPM]":"15.8","Cell RNA - RPTEC TERT1 [nTPM]":"4.6","Cell RNA - RT4 [nTPM]":"8.8","Cell RNA - SCLC-21H [nTPM]":"1.6","Cell RNA - SH-SY5Y [nTPM]":"20.4","Cell RNA - SiHa [nTPM]":"11.9","Cell RNA - SK-BR-3 [nTPM]":"2.8","Cell RNA - SK-MEL-30 [nTPM]":"6.0","Cell RNA - SuSa [nTPM]":"3.3","Cell RNA - T-47d [nTPM]":"2.2","Cell RNA - THP-1 [nTPM]":"1.3","Cell RNA - TIME [nTPM]":"9.4","Cell RNA - U-138 MG [nTPM]":"3.7","Cell RNA - U-2 OS [nTPM]":"3.6","Cell RNA - U-2197 [nTPM]":"5.2","Cell RNA - U-251 MG [nTPM]":"1.9","Cell RNA - U-266\/70 [nTPM]":"5.6","Cell RNA - U-266\/84 [nTPM]":"10.7","Cell RNA - U-698 [nTPM]":"5.2","Cell RNA - U-87 MG [nTPM]":"6.0","Cell RNA - U-937 [nTPM]":"2.5","Cell RNA - WM-115 [nTPM]":"5.7","Blood RNA - basophil [nTPM]":"7.1","Blood RNA - classical monocyte [nTPM]":"1.5","Blood RNA - eosinophil [nTPM]":"4.5","Blood RNA - gdT-cell [nTPM]":"1.8","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"0.9","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.2","Blood RNA - memory CD8 T-cell [nTPM]":"1.2","Blood RNA - myeloid DC [nTPM]":"1.0","Blood RNA - naive B-cell [nTPM]":"1.4","Blood RNA - naive CD4 T-cell [nTPM]":"1.4","Blood RNA - naive CD8 T-cell [nTPM]":"2.1","Blood RNA - neutrophil [nTPM]":"8.1","Blood RNA - NK-cell [nTPM]":"1.2","Blood RNA - non-classical monocyte [nTPM]":"1.9","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"1.2","Brain RNA - basal ganglia [nTPM]":"1.7","Brain RNA - cerebellum [nTPM]":"2.3","Brain RNA - cerebral cortex [nTPM]":"2.1","Brain RNA - hippocampal formation [nTPM]":"1.3","Brain RNA - hypothalamus [nTPM]":"2.1","Brain RNA - medulla oblongata [nTPM]":"2.1","Brain RNA - midbrain [nTPM]":"2.1","Brain RNA - pons [nTPM]":"3.8","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"1.6","Brain RNA - white matter [nTPM]":"2.9","Single Cell Type RNA - Adipocytes [nTPM]":"14.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.4","Single Cell Type RNA - Astrocytes [nTPM]":"15.7","Single Cell Type RNA - B-cells [nTPM]":"12.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Bipolar cells [nTPM]":"6.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"8.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.0","Single Cell Type RNA - dendritic cells [nTPM]":"15.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.2","Single Cell Type RNA - Endothelial cells [nTPM]":"9.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"22.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.2","Single Cell Type RNA - Fibroblasts [nTPM]":"9.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.8","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"6.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"3.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.3","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.8","Single Cell Type RNA - Ionocytes [nTPM]":"61.1","Single Cell Type RNA - Kupffer cells [nTPM]":"11.7","Single Cell Type RNA - Langerhans cells [nTPM]":"6.7","Single Cell Type RNA - Late spermatids [nTPM]":"1.1","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"12.6","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"44.0","Single Cell Type RNA - monocytes [nTPM]":"5.5","Single Cell Type RNA - Muller glia cells [nTPM]":"4.4","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"37.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"35.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.2","Single Cell Type RNA - Paneth cells [nTPM]":"4.1","Single Cell Type RNA - Peritubular cells [nTPM]":"9.8","Single Cell Type RNA - Plasma cells [nTPM]":"10.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.1","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.7","Single Cell Type RNA - Spermatocytes [nTPM]":"1.8","Single Cell Type RNA - Spermatogonia [nTPM]":"5.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.2","Single Cell Type RNA - T-cells [nTPM]":"13.8","Single Cell Type RNA - Theca cells [nTPM]":"6.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.2","Single Cell Type RNA - Urothelial cells [nTPM]":"6.6"},{"Gene":"ATP7B","Gene synonym":["WND"],"Ensembl":"ENSG00000123191","Gene description":"ATPase copper transporting beta","Uniprot":["P35670"],"Chromosome":"13","Position":"51930436-52012125","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Copper transport","Ion transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"22.9","Early spermatids":"30.2","Excitatory neurons":"24.5","Hepatocytes":"23.6","Inhibitory neurons":"25.4","Late spermatids":"74.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"32.8","CACO-2":"21.1","HEL":"53.0","RPTEC TERT1":"22.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009137","HPA013187"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA009137":"AB_2668214","HPA013187":"AB_1845206"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.01e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.6","Tissue RNA - adrenal gland [nTPM]":"0.9","Tissue RNA - amygdala [nTPM]":"1.3","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"1.2","Tissue RNA - bone marrow [nTPM]":"2.2","Tissue RNA - breast [nTPM]":"1.7","Tissue RNA - cerebellum [nTPM]":"2.0","Tissue RNA - cerebral cortex [nTPM]":"2.1","Tissue RNA - cervix [nTPM]":"1.8","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"2.9","Tissue RNA - duodenum [nTPM]":"10.6","Tissue RNA - endometrium 1 [nTPM]":"1.5","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.7","Tissue RNA - fallopian tube [nTPM]":"2.0","Tissue RNA - gallbladder [nTPM]":"7.0","Tissue RNA - heart muscle [nTPM]":"2.1","Tissue RNA - hippocampal formation [nTPM]":"2.5","Tissue RNA - hypothalamus [nTPM]":"1.4","Tissue RNA - kidney [nTPM]":"2.2","Tissue RNA - liver [nTPM]":"8.6","Tissue RNA - lung [nTPM]":"1.4","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"0.8","Tissue RNA - midbrain [nTPM]":"1.2","Tissue RNA - ovary [nTPM]":"1.9","Tissue RNA - pancreas [nTPM]":"2.0","Tissue RNA - parathyroid gland [nTPM]":"6.4","Tissue RNA - pituitary gland [nTPM]":"1.2","Tissue RNA - placenta [nTPM]":"7.1","Tissue RNA - pons [nTPM]":"1.1","Tissue RNA - prostate [nTPM]":"2.0","Tissue RNA - rectum [nTPM]":"2.7","Tissue RNA - retina [nTPM]":"3.7","Tissue RNA - salivary gland [nTPM]":"3.0","Tissue RNA - seminal vesicle [nTPM]":"0.9","Tissue RNA - skeletal muscle [nTPM]":"1.1","Tissue RNA - skin 1 [nTPM]":"1.0","Tissue RNA - small intestine [nTPM]":"6.0","Tissue RNA - smooth muscle [nTPM]":"1.7","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"4.4","Tissue RNA - testis [nTPM]":"8.4","Tissue RNA - thalamus [nTPM]":"1.7","Tissue RNA - thymus [nTPM]":"0.7","Tissue RNA - thyroid gland [nTPM]":"1.2","Tissue RNA - tongue [nTPM]":"1.8","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"1.6","Tissue RNA - vagina [nTPM]":"1.2","Tissue RNA - white matter [nTPM]":"0.7","Cell RNA - A-431 [nTPM]":"0.8","Cell RNA - A549 [nTPM]":"2.8","Cell RNA - AF22 [nTPM]":"5.2","Cell RNA - AN3-CA [nTPM]":"4.5","Cell RNA - ASC diff [nTPM]":"1.0","Cell RNA - ASC TERT1 [nTPM]":"0.8","Cell RNA - BEWO [nTPM]":"32.8","Cell RNA - BJ [nTPM]":"1.5","Cell RNA - BJ hTERT+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.2","Cell RNA - CACO-2 [nTPM]":"21.1","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.6","Cell RNA - fHDF\/TERT166 [nTPM]":"2.7","Cell RNA - GAMG [nTPM]":"3.6","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"4.0","Cell RNA - HBEC3-KT [nTPM]":"4.4","Cell RNA - HBF TERT88 [nTPM]":"1.0","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"7.5","Cell RNA - HEL [nTPM]":"53.0","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"14.7","Cell RNA - HHSteC [nTPM]":"1.4","Cell RNA - HL-60 [nTPM]":"0.6","Cell RNA - HMC-1 [nTPM]":"11.8","Cell RNA - HSkMC [nTPM]":"1.9","Cell RNA - hTCEpi [nTPM]":"4.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"2.0","Cell RNA - hTERT-RPE1 [nTPM]":"2.1","Cell RNA - HUVEC TERT2 [nTPM]":"3.7","Cell RNA - JURKAT [nTPM]":"3.7","Cell RNA - K-562 [nTPM]":"14.4","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"1.5","Cell RNA - MCF7 [nTPM]":"1.0","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.9","Cell RNA - NTERA-2 [nTPM]":"1.7","Cell RNA - OE19 [nTPM]":"6.6","Cell RNA - PC-3 [nTPM]":"1.8","Cell RNA - REH [nTPM]":"2.0","Cell RNA - RH-30 [nTPM]":"1.4","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"22.5","Cell RNA - RT4 [nTPM]":"3.4","Cell RNA - SCLC-21H [nTPM]":"3.3","Cell RNA - SH-SY5Y [nTPM]":"2.2","Cell RNA - SiHa [nTPM]":"1.9","Cell RNA - SK-BR-3 [nTPM]":"2.8","Cell RNA - SK-MEL-30 [nTPM]":"1.8","Cell RNA - SuSa [nTPM]":"5.5","Cell RNA - T-47d [nTPM]":"8.0","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"2.0","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"1.7","Cell RNA - U-2197 [nTPM]":"2.8","Cell RNA - U-251 MG [nTPM]":"0.6","Cell RNA - U-266\/70 [nTPM]":"0.6","Cell RNA - U-266\/84 [nTPM]":"0.7","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.3","Brain RNA - basal ganglia [nTPM]":"1.2","Brain RNA - cerebellum [nTPM]":"2.0","Brain RNA - cerebral cortex [nTPM]":"2.1","Brain RNA - hippocampal formation [nTPM]":"2.5","Brain RNA - hypothalamus [nTPM]":"1.4","Brain RNA - medulla oblongata [nTPM]":"0.8","Brain RNA - midbrain [nTPM]":"1.2","Brain RNA - pons [nTPM]":"1.1","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"1.7","Brain RNA - white matter [nTPM]":"0.7","Single Cell Type RNA - Adipocytes [nTPM]":"5.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"0.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"3.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"5.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.3","Single Cell Type RNA - dendritic cells [nTPM]":"1.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.6","Single Cell Type RNA - Early spermatids [nTPM]":"30.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.3","Single Cell Type RNA - Endothelial cells [nTPM]":"2.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"4.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"24.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.5","Single Cell Type RNA - Fibroblasts [nTPM]":"2.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"13.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"23.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.4","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"74.2","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.0","Single Cell Type RNA - Paneth cells [nTPM]":"3.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.4","Single Cell Type RNA - Spermatocytes [nTPM]":"2.2","Single Cell Type RNA - Spermatogonia [nTPM]":"1.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.5","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.2"},{"Gene":"ATP8A2","Gene synonym":["ATPIB","ML-1"],"Ensembl":"ENSG00000132932","Gene description":"ATPase phospholipid transporting 8A2","Uniprot":["Q9NTI2"],"Chromosome":"13","Position":"25371974-26025851","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"21.6","pituitary gland":"15.2","retina":"17.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Excitatory neurons":"518.7","Inhibitory neurons":"727.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"19.9","JURKAT":"9.8","MOLT-4":"3.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039926","HPA040033"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA039926":"AB_10794205","HPA040033":"AB_2676809"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"2.1","Tissue RNA - amygdala [nTPM]":"5.5","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"6.7","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.6","Tissue RNA - cerebellum [nTPM]":"8.0","Tissue RNA - cerebral cortex [nTPM]":"21.6","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.6","Tissue RNA - epididymis [nTPM]":"1.8","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"8.7","Tissue RNA - hypothalamus [nTPM]":"19.3","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.8","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"12.8","Tissue RNA - midbrain [nTPM]":"4.6","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.6","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"15.2","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"12.1","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"17.2","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"0.6","Tissue RNA - testis [nTPM]":"2.9","Tissue RNA - thalamus [nTPM]":"6.6","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"6.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.7","Cell RNA - EFO-21 [nTPM]":"1.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"1.5","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.8","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"19.9","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.5","Cell RNA - JURKAT [nTPM]":"9.8","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"1.7","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"3.9","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"2.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.7","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"2.7","Cell RNA - RPMI-8226 [nTPM]":"0.9","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"3.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.0","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"5.5","Brain RNA - basal ganglia [nTPM]":"6.7","Brain RNA - cerebellum [nTPM]":"8.0","Brain RNA - cerebral cortex [nTPM]":"21.6","Brain RNA - hippocampal formation [nTPM]":"8.7","Brain RNA - hypothalamus [nTPM]":"19.3","Brain RNA - medulla oblongata [nTPM]":"12.8","Brain RNA - midbrain [nTPM]":"4.6","Brain RNA - pons [nTPM]":"12.1","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"6.6","Brain RNA - white matter [nTPM]":"6.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.2","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"0.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"21.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"95.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"39.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.6","Single Cell Type RNA - Endothelial cells [nTPM]":"2.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"518.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"1.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.9","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"3.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.2","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"727.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"30.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"7.2","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"88.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"24.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"91.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.8","Single Cell Type RNA - Spermatocytes [nTPM]":"19.8","Single Cell Type RNA - Spermatogonia [nTPM]":"12.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - T-cells [nTPM]":"1.8","Single Cell Type RNA - Theca cells [nTPM]":"10.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"ATP8B1","Gene synonym":["ATPIC","BRIC","FIC1","PFIC","PFIC1"],"Ensembl":"ENSG00000081923","Gene description":"ATPase phospholipid transporting 8B1","Uniprot":["O43520"],"Chromosome":"18","Position":"57646426-57803315","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Hearing","Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Intrahepatic cholestasis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"76.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"279.7","Intestinal goblet cells":"180.5","Paneth cells":"116.7","Undifferentiated cells":"185.7","Urothelial cells":"119.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"fHDF\/TERT166":"90.2","RT4":"168.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018673","HPA018674"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoplasm","Nuclear bodies"],"Antibody RRID":{"HPA018673":"AB_1845207","HPA018674":"AB_1845208"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.60e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.62e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.35e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-3"},"Tissue RNA - adipose tissue [nTPM]":"9.1","Tissue RNA - adrenal gland [nTPM]":"5.4","Tissue RNA - amygdala [nTPM]":"1.3","Tissue RNA - appendix [nTPM]":"8.5","Tissue RNA - basal ganglia [nTPM]":"2.0","Tissue RNA - bone marrow [nTPM]":"1.2","Tissue RNA - breast [nTPM]":"9.5","Tissue RNA - cerebellum [nTPM]":"3.6","Tissue RNA - cerebral cortex [nTPM]":"3.9","Tissue RNA - cervix [nTPM]":"16.3","Tissue RNA - choroid plexus [nTPM]":"3.0","Tissue RNA - colon [nTPM]":"76.2","Tissue RNA - duodenum [nTPM]":"30.3","Tissue RNA - endometrium 1 [nTPM]":"5.9","Tissue RNA - epididymis [nTPM]":"3.5","Tissue RNA - esophagus [nTPM]":"14.8","Tissue RNA - fallopian tube [nTPM]":"10.6","Tissue RNA - gallbladder [nTPM]":"18.0","Tissue RNA - heart muscle [nTPM]":"4.4","Tissue RNA - hippocampal formation [nTPM]":"1.7","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"6.6","Tissue RNA - liver [nTPM]":"7.7","Tissue RNA - lung [nTPM]":"8.3","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"2.1","Tissue RNA - midbrain [nTPM]":"1.1","Tissue RNA - ovary [nTPM]":"2.1","Tissue RNA - pancreas [nTPM]":"23.3","Tissue RNA - parathyroid gland [nTPM]":"9.7","Tissue RNA - pituitary gland [nTPM]":"2.7","Tissue RNA - placenta [nTPM]":"6.9","Tissue RNA - pons [nTPM]":"2.0","Tissue RNA - prostate [nTPM]":"17.6","Tissue RNA - rectum [nTPM]":"61.7","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"20.6","Tissue RNA - seminal vesicle [nTPM]":"11.5","Tissue RNA - skeletal muscle [nTPM]":"1.9","Tissue RNA - skin 1 [nTPM]":"8.4","Tissue RNA - small intestine [nTPM]":"38.2","Tissue RNA - smooth muscle [nTPM]":"8.3","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"4.6","Tissue RNA - stomach 1 [nTPM]":"46.1","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"1.9","Tissue RNA - thymus [nTPM]":"1.5","Tissue RNA - thyroid gland [nTPM]":"22.0","Tissue RNA - tongue [nTPM]":"1.8","Tissue RNA - tonsil [nTPM]":"3.6","Tissue RNA - urinary bladder [nTPM]":"30.0","Tissue RNA - vagina [nTPM]":"13.0","Tissue RNA - white matter [nTPM]":"3.0","Cell RNA - A-431 [nTPM]":"32.0","Cell RNA - A549 [nTPM]":"10.7","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.6","Cell RNA - ASC diff [nTPM]":"10.5","Cell RNA - ASC TERT1 [nTPM]":"19.2","Cell RNA - BEWO [nTPM]":"11.9","Cell RNA - BJ [nTPM]":"62.6","Cell RNA - BJ hTERT+ [nTPM]":"63.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"67.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"40.4","Cell RNA - CACO-2 [nTPM]":"8.0","Cell RNA - CAPAN-2 [nTPM]":"24.3","Cell RNA - Daudi [nTPM]":"1.5","Cell RNA - EFO-21 [nTPM]":"19.3","Cell RNA - fHDF\/TERT166 [nTPM]":"90.2","Cell RNA - GAMG [nTPM]":"22.3","Cell RNA - HaCaT [nTPM]":"44.9","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"13.9","Cell RNA - HBF TERT88 [nTPM]":"64.3","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"1.1","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"2.6","Cell RNA - Hep G2 [nTPM]":"2.5","Cell RNA - HHSteC [nTPM]":"2.2","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"2.9","Cell RNA - hTCEpi [nTPM]":"12.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.8","Cell RNA - hTERT-HME1 [nTPM]":"34.0","Cell RNA - hTERT-RPE1 [nTPM]":"39.5","Cell RNA - HUVEC TERT2 [nTPM]":"33.0","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"34.1","Cell RNA - MCF7 [nTPM]":"15.6","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"35.5","Cell RNA - PC-3 [nTPM]":"3.3","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"7.9","Cell RNA - RT4 [nTPM]":"168.1","Cell RNA - SCLC-21H [nTPM]":"0.8","Cell RNA - SH-SY5Y [nTPM]":"0.7","Cell RNA - SiHa [nTPM]":"1.3","Cell RNA - SK-BR-3 [nTPM]":"32.5","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"10.3","Cell RNA - THP-1 [nTPM]":"0.6","Cell RNA - TIME [nTPM]":"35.3","Cell RNA - U-138 MG [nTPM]":"48.3","Cell RNA - U-2 OS [nTPM]":"2.0","Cell RNA - U-2197 [nTPM]":"7.7","Cell RNA - U-251 MG [nTPM]":"14.2","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"1.1","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"2.8","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.3","Brain RNA - basal ganglia [nTPM]":"2.0","Brain RNA - cerebellum [nTPM]":"3.6","Brain RNA - cerebral cortex [nTPM]":"3.9","Brain RNA - hippocampal formation [nTPM]":"1.7","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"2.1","Brain RNA - midbrain [nTPM]":"1.1","Brain RNA - pons [nTPM]":"2.0","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"1.9","Brain RNA - white matter [nTPM]":"3.0","Single Cell Type RNA - Adipocytes [nTPM]":"25.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.0","Single Cell Type RNA - Astrocytes [nTPM]":"11.1","Single Cell Type RNA - B-cells [nTPM]":"4.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"66.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"20.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"28.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"48.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"279.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"27.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"26.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.0","Single Cell Type RNA - Endothelial cells [nTPM]":"30.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"68.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"61.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"53.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.7","Single Cell Type RNA - Fibroblasts [nTPM]":"7.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"98.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"40.1","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"33.2","Single Cell Type RNA - Hepatocytes [nTPM]":"19.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.4","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"180.5","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"2.8","Single Cell Type RNA - Langerhans cells [nTPM]":"4.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"37.5","Single Cell Type RNA - monocytes [nTPM]":"0.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"38.5","Single Cell Type RNA - Paneth cells [nTPM]":"116.7","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"70.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"58.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"44.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.9","Single Cell Type RNA - T-cells [nTPM]":"1.7","Single Cell Type RNA - Theca cells [nTPM]":"2.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"185.7","Single Cell Type RNA - Urothelial cells [nTPM]":"119.2"},{"Gene":"ATR","Gene synonym":["FRP1","MEC1","SCKL","SCKL1"],"Ensembl":"ENSG00000175054","Gene description":"ATR serine\/threonine kinase","Uniprot":["Q13535"],"Chromosome":"3","Position":"142449007-142578733","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["DNA-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Dwarfism","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"93.0","Inhibitory neurons":"94.4","Microglial cells":"73.1","Oligodendrocyte precursor cells":"65.4","Oligodendrocytes":"71.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054320"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA054320":"AB_2682448"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.39e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.23e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.0","Tissue RNA - adrenal gland [nTPM]":"8.6","Tissue RNA - amygdala [nTPM]":"0.7","Tissue RNA - appendix [nTPM]":"4.1","Tissue RNA - basal ganglia [nTPM]":"1.1","Tissue RNA - bone marrow [nTPM]":"1.2","Tissue RNA - breast [nTPM]":"3.2","Tissue RNA - cerebellum [nTPM]":"0.9","Tissue RNA - cerebral cortex [nTPM]":"1.4","Tissue RNA - cervix [nTPM]":"3.8","Tissue RNA - choroid plexus [nTPM]":"3.7","Tissue RNA - colon [nTPM]":"2.7","Tissue RNA - duodenum [nTPM]":"1.7","Tissue RNA - endometrium 1 [nTPM]":"3.3","Tissue RNA - epididymis [nTPM]":"2.3","Tissue RNA - esophagus [nTPM]":"3.1","Tissue RNA - fallopian tube [nTPM]":"3.3","Tissue RNA - gallbladder [nTPM]":"3.4","Tissue RNA - heart muscle [nTPM]":"2.3","Tissue RNA - hippocampal formation [nTPM]":"1.2","Tissue RNA - hypothalamus [nTPM]":"1.9","Tissue RNA - kidney [nTPM]":"3.7","Tissue RNA - liver [nTPM]":"3.6","Tissue RNA - lung [nTPM]":"2.9","Tissue RNA - lymph node [nTPM]":"4.8","Tissue RNA - medulla oblongata [nTPM]":"1.5","Tissue RNA - midbrain [nTPM]":"1.2","Tissue RNA - ovary [nTPM]":"2.7","Tissue RNA - pancreas [nTPM]":"3.8","Tissue RNA - parathyroid gland [nTPM]":"5.2","Tissue RNA - pituitary gland [nTPM]":"3.7","Tissue RNA - placenta [nTPM]":"3.1","Tissue RNA - pons [nTPM]":"1.4","Tissue RNA - prostate [nTPM]":"3.0","Tissue RNA - rectum [nTPM]":"2.9","Tissue RNA - retina [nTPM]":"2.9","Tissue RNA - salivary gland [nTPM]":"3.5","Tissue RNA - seminal vesicle [nTPM]":"2.5","Tissue RNA - skeletal muscle [nTPM]":"2.9","Tissue RNA - skin 1 [nTPM]":"2.7","Tissue RNA - small intestine [nTPM]":"3.1","Tissue RNA - smooth muscle [nTPM]":"3.2","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"4.2","Tissue RNA - stomach 1 [nTPM]":"2.8","Tissue RNA - testis [nTPM]":"5.2","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"4.9","Tissue RNA - thyroid gland [nTPM]":"5.0","Tissue RNA - tongue [nTPM]":"1.4","Tissue RNA - tonsil [nTPM]":"4.6","Tissue RNA - urinary bladder [nTPM]":"4.1","Tissue RNA - vagina [nTPM]":"2.7","Tissue RNA - white matter [nTPM]":"1.2","Cell RNA - A-431 [nTPM]":"28.6","Cell RNA - A549 [nTPM]":"13.2","Cell RNA - AF22 [nTPM]":"7.1","Cell RNA - AN3-CA [nTPM]":"7.0","Cell RNA - ASC diff [nTPM]":"9.6","Cell RNA - ASC TERT1 [nTPM]":"13.6","Cell RNA - BEWO [nTPM]":"8.8","Cell RNA - BJ [nTPM]":"14.8","Cell RNA - BJ hTERT+ [nTPM]":"8.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.7","Cell RNA - CACO-2 [nTPM]":"6.4","Cell RNA - CAPAN-2 [nTPM]":"6.8","Cell RNA - Daudi [nTPM]":"19.9","Cell RNA - EFO-21 [nTPM]":"14.6","Cell RNA - fHDF\/TERT166 [nTPM]":"10.1","Cell RNA - GAMG [nTPM]":"14.6","Cell RNA - HaCaT [nTPM]":"16.1","Cell RNA - HAP1 [nTPM]":"10.9","Cell RNA - HBEC3-KT [nTPM]":"12.8","Cell RNA - HBF TERT88 [nTPM]":"15.0","Cell RNA - HDLM-2 [nTPM]":"7.5","Cell RNA - HEK 293 [nTPM]":"7.9","Cell RNA - HEL [nTPM]":"11.9","Cell RNA - HeLa [nTPM]":"8.2","Cell RNA - Hep G2 [nTPM]":"4.1","Cell RNA - HHSteC [nTPM]":"4.2","Cell RNA - HL-60 [nTPM]":"20.5","Cell RNA - HMC-1 [nTPM]":"5.3","Cell RNA - HSkMC [nTPM]":"9.8","Cell RNA - hTCEpi [nTPM]":"4.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.5","Cell RNA - hTERT-HME1 [nTPM]":"10.3","Cell RNA - hTERT-RPE1 [nTPM]":"5.8","Cell RNA - HUVEC TERT2 [nTPM]":"11.6","Cell RNA - JURKAT [nTPM]":"8.7","Cell RNA - K-562 [nTPM]":"8.2","Cell RNA - Karpas-707 [nTPM]":"7.5","Cell RNA - LHCN-M2 [nTPM]":"9.6","Cell RNA - MCF7 [nTPM]":"7.5","Cell RNA - MOLT-4 [nTPM]":"13.9","Cell RNA - NB-4 [nTPM]":"2.6","Cell RNA - NTERA-2 [nTPM]":"7.3","Cell RNA - OE19 [nTPM]":"15.6","Cell RNA - PC-3 [nTPM]":"9.6","Cell RNA - REH [nTPM]":"11.8","Cell RNA - RH-30 [nTPM]":"12.5","Cell RNA - RPMI-8226 [nTPM]":"13.5","Cell RNA - RPTEC TERT1 [nTPM]":"6.3","Cell RNA - RT4 [nTPM]":"11.1","Cell RNA - SCLC-21H [nTPM]":"5.2","Cell RNA - SH-SY5Y [nTPM]":"5.1","Cell RNA - SiHa [nTPM]":"28.6","Cell RNA - SK-BR-3 [nTPM]":"8.3","Cell RNA - SK-MEL-30 [nTPM]":"8.0","Cell RNA - SuSa [nTPM]":"7.8","Cell RNA - T-47d [nTPM]":"12.0","Cell RNA - THP-1 [nTPM]":"5.4","Cell RNA - TIME [nTPM]":"14.6","Cell RNA - U-138 MG [nTPM]":"10.5","Cell RNA - U-2 OS [nTPM]":"4.9","Cell RNA - U-2197 [nTPM]":"12.3","Cell RNA - U-251 MG [nTPM]":"15.2","Cell RNA - U-266\/70 [nTPM]":"10.8","Cell RNA - U-266\/84 [nTPM]":"7.4","Cell RNA - U-698 [nTPM]":"18.5","Cell RNA - U-87 MG [nTPM]":"13.8","Cell RNA - U-937 [nTPM]":"6.5","Cell RNA - WM-115 [nTPM]":"8.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.3","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"0.7","Brain RNA - basal ganglia [nTPM]":"1.1","Brain RNA - cerebellum [nTPM]":"0.9","Brain RNA - cerebral cortex [nTPM]":"1.4","Brain RNA - hippocampal formation [nTPM]":"1.2","Brain RNA - hypothalamus [nTPM]":"1.9","Brain RNA - medulla oblongata [nTPM]":"1.5","Brain RNA - midbrain [nTPM]":"1.2","Brain RNA - pons [nTPM]":"1.4","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"1.2","Single Cell Type RNA - Adipocytes [nTPM]":"11.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.6","Single Cell Type RNA - Astrocytes [nTPM]":"39.2","Single Cell Type RNA - B-cells [nTPM]":"22.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"14.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"10.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.7","Single Cell Type RNA - dendritic cells [nTPM]":"14.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.9","Single Cell Type RNA - Early spermatids [nTPM]":"16.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.6","Single Cell Type RNA - Endothelial cells [nTPM]":"10.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.7","Single Cell Type RNA - Erythroid cells [nTPM]":"14.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"93.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.6","Single Cell Type RNA - Fibroblasts [nTPM]":"8.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.3","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"16.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"7.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.4","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"94.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.8","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"9.4","Single Cell Type RNA - Langerhans cells [nTPM]":"4.0","Single Cell Type RNA - Late spermatids [nTPM]":"8.7","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"12.8","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"73.1","Single Cell Type RNA - monocytes [nTPM]":"12.0","Single Cell Type RNA - Muller glia cells [nTPM]":"6.0","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"65.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"71.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.4","Single Cell Type RNA - Paneth cells [nTPM]":"1.8","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"23.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"25.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.8","Single Cell Type RNA - Spermatocytes [nTPM]":"50.1","Single Cell Type RNA - Spermatogonia [nTPM]":"18.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.1","Single Cell Type RNA - T-cells [nTPM]":"15.1","Single Cell Type RNA - Theca cells [nTPM]":"13.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.6","Single Cell Type RNA - Urothelial cells [nTPM]":"6.1"},{"Gene":"ATRX","Gene synonym":["JMS","MRX52","RAD54","XH2","XNP"],"Ensembl":"ENSG00000085224","Gene description":"ATRX chromatin remodeler","Uniprot":["P46100"],"Chromosome":"X","Position":"77504880-77786233","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transcription factors"],"Biological process":["DNA damage","DNA repair","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001906","CAB009372","HPA064684","CAB068176"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"CAB009372":"AB_2061023","CAB068176":"AB_2665665","HPA001906":"AB_1078249","HPA064684":"AB_2685321"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Tissue RNA - adipose tissue [nTPM]":"18.0","Tissue RNA - adrenal gland [nTPM]":"15.9","Tissue RNA - amygdala [nTPM]":"17.3","Tissue RNA - appendix [nTPM]":"17.6","Tissue RNA - basal ganglia [nTPM]":"20.4","Tissue RNA - bone marrow [nTPM]":"29.9","Tissue RNA - breast [nTPM]":"18.1","Tissue RNA - cerebellum [nTPM]":"32.9","Tissue RNA - cerebral cortex [nTPM]":"20.4","Tissue RNA - cervix [nTPM]":"18.0","Tissue RNA - choroid plexus [nTPM]":"21.4","Tissue RNA - colon [nTPM]":"12.7","Tissue RNA - duodenum [nTPM]":"11.2","Tissue RNA - endometrium 1 [nTPM]":"21.2","Tissue RNA - epididymis [nTPM]":"14.8","Tissue RNA - esophagus [nTPM]":"13.3","Tissue RNA - fallopian tube [nTPM]":"11.8","Tissue RNA - gallbladder [nTPM]":"14.7","Tissue RNA - heart muscle [nTPM]":"15.5","Tissue RNA - hippocampal formation [nTPM]":"19.2","Tissue RNA - hypothalamus [nTPM]":"19.8","Tissue RNA - kidney [nTPM]":"16.9","Tissue RNA - liver [nTPM]":"13.2","Tissue RNA - lung [nTPM]":"13.4","Tissue RNA - lymph node [nTPM]":"22.6","Tissue RNA - medulla oblongata [nTPM]":"15.0","Tissue RNA - midbrain [nTPM]":"20.1","Tissue RNA - ovary [nTPM]":"24.9","Tissue RNA - pancreas [nTPM]":"13.4","Tissue RNA - parathyroid gland [nTPM]":"23.2","Tissue RNA - pituitary gland [nTPM]":"8.5","Tissue RNA - placenta [nTPM]":"16.6","Tissue RNA - pons [nTPM]":"16.6","Tissue RNA - prostate [nTPM]":"19.2","Tissue RNA - rectum [nTPM]":"13.5","Tissue RNA - retina [nTPM]":"26.8","Tissue RNA - salivary gland [nTPM]":"14.0","Tissue RNA - seminal vesicle [nTPM]":"14.8","Tissue RNA - skeletal muscle [nTPM]":"19.1","Tissue RNA - skin 1 [nTPM]":"15.6","Tissue RNA - small intestine [nTPM]":"10.9","Tissue RNA - smooth muscle [nTPM]":"15.6","Tissue RNA - spinal cord [nTPM]":"16.4","Tissue RNA - spleen [nTPM]":"22.8","Tissue RNA - stomach 1 [nTPM]":"16.5","Tissue RNA - testis [nTPM]":"6.6","Tissue RNA - thalamus [nTPM]":"22.6","Tissue RNA - thymus [nTPM]":"25.7","Tissue RNA - thyroid gland [nTPM]":"20.0","Tissue RNA - tongue [nTPM]":"26.9","Tissue RNA - tonsil [nTPM]":"18.6","Tissue RNA - urinary bladder [nTPM]":"14.1","Tissue RNA - vagina [nTPM]":"9.9","Tissue RNA - white matter [nTPM]":"19.7","Cell RNA - A-431 [nTPM]":"36.0","Cell RNA - A549 [nTPM]":"55.1","Cell RNA - AF22 [nTPM]":"60.1","Cell RNA - AN3-CA [nTPM]":"45.0","Cell RNA - ASC diff [nTPM]":"31.8","Cell RNA - ASC TERT1 [nTPM]":"38.1","Cell RNA - BEWO [nTPM]":"21.2","Cell RNA - BJ [nTPM]":"29.4","Cell RNA - BJ hTERT+ [nTPM]":"27.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"25.9","Cell RNA - CACO-2 [nTPM]":"19.6","Cell RNA - CAPAN-2 [nTPM]":"30.7","Cell RNA - Daudi [nTPM]":"48.5","Cell RNA - EFO-21 [nTPM]":"29.9","Cell RNA - fHDF\/TERT166 [nTPM]":"32.5","Cell RNA - GAMG [nTPM]":"39.9","Cell RNA - HaCaT [nTPM]":"30.0","Cell RNA - HAP1 [nTPM]":"44.6","Cell RNA - HBEC3-KT [nTPM]":"18.1","Cell RNA - HBF TERT88 [nTPM]":"37.5","Cell RNA - HDLM-2 [nTPM]":"27.3","Cell RNA - HEK 293 [nTPM]":"30.8","Cell RNA - HEL [nTPM]":"29.3","Cell RNA - HeLa [nTPM]":"67.2","Cell RNA - Hep G2 [nTPM]":"16.2","Cell RNA - HHSteC [nTPM]":"16.1","Cell RNA - HL-60 [nTPM]":"38.4","Cell RNA - HMC-1 [nTPM]":"10.2","Cell RNA - HSkMC [nTPM]":"25.5","Cell RNA - hTCEpi [nTPM]":"20.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.2","Cell RNA - hTERT-HME1 [nTPM]":"30.4","Cell RNA - hTERT-RPE1 [nTPM]":"29.4","Cell RNA - HUVEC TERT2 [nTPM]":"41.9","Cell RNA - JURKAT [nTPM]":"30.3","Cell RNA - K-562 [nTPM]":"34.9","Cell RNA - Karpas-707 [nTPM]":"53.3","Cell RNA - LHCN-M2 [nTPM]":"29.3","Cell RNA - MCF7 [nTPM]":"27.6","Cell RNA - MOLT-4 [nTPM]":"30.2","Cell RNA - NB-4 [nTPM]":"25.0","Cell RNA - NTERA-2 [nTPM]":"42.0","Cell RNA - OE19 [nTPM]":"17.6","Cell RNA - PC-3 [nTPM]":"42.5","Cell RNA - REH [nTPM]":"48.6","Cell RNA - RH-30 [nTPM]":"76.3","Cell RNA - RPMI-8226 [nTPM]":"26.0","Cell RNA - RPTEC TERT1 [nTPM]":"25.6","Cell RNA - RT4 [nTPM]":"46.4","Cell RNA - SCLC-21H [nTPM]":"33.1","Cell RNA - SH-SY5Y [nTPM]":"55.5","Cell RNA - SiHa [nTPM]":"60.5","Cell RNA - SK-BR-3 [nTPM]":"23.1","Cell RNA - SK-MEL-30 [nTPM]":"21.9","Cell RNA - SuSa [nTPM]":"37.2","Cell RNA - T-47d [nTPM]":"18.6","Cell RNA - THP-1 [nTPM]":"20.8","Cell RNA - TIME [nTPM]":"55.8","Cell RNA - U-138 MG [nTPM]":"32.8","Cell RNA - U-2 OS [nTPM]":"76.1","Cell RNA - U-2197 [nTPM]":"34.4","Cell RNA - U-251 MG [nTPM]":"21.0","Cell RNA - U-266\/70 [nTPM]":"16.3","Cell RNA - U-266\/84 [nTPM]":"52.9","Cell RNA - U-698 [nTPM]":"42.1","Cell RNA - U-87 MG [nTPM]":"23.0","Cell RNA - U-937 [nTPM]":"30.9","Cell RNA - WM-115 [nTPM]":"27.8","Blood RNA - basophil [nTPM]":"44.0","Blood RNA - classical monocyte [nTPM]":"10.5","Blood RNA - eosinophil [nTPM]":"22.7","Blood RNA - gdT-cell [nTPM]":"26.0","Blood RNA - intermediate monocyte [nTPM]":"13.3","Blood RNA - MAIT T-cell [nTPM]":"25.2","Blood RNA - memory B-cell [nTPM]":"31.2","Blood RNA - memory CD4 T-cell [nTPM]":"24.0","Blood RNA - memory CD8 T-cell [nTPM]":"20.9","Blood RNA - myeloid DC [nTPM]":"8.1","Blood RNA - naive B-cell [nTPM]":"32.4","Blood RNA - naive CD4 T-cell [nTPM]":"24.6","Blood RNA - naive CD8 T-cell [nTPM]":"20.1","Blood RNA - neutrophil [nTPM]":"33.2","Blood RNA - NK-cell [nTPM]":"23.2","Blood RNA - non-classical monocyte [nTPM]":"20.0","Blood RNA - plasmacytoid DC [nTPM]":"20.7","Blood RNA - T-reg [nTPM]":"22.2","Blood RNA - total PBMC [nTPM]":"9.7","Brain RNA - amygdala [nTPM]":"17.3","Brain RNA - basal ganglia [nTPM]":"20.4","Brain RNA - cerebellum [nTPM]":"32.9","Brain RNA - cerebral cortex [nTPM]":"20.4","Brain RNA - hippocampal formation [nTPM]":"19.2","Brain RNA - hypothalamus [nTPM]":"19.8","Brain RNA - medulla oblongata [nTPM]":"15.0","Brain RNA - midbrain [nTPM]":"20.1","Brain RNA - pons [nTPM]":"16.6","Brain RNA - spinal cord [nTPM]":"16.4","Brain RNA - thalamus [nTPM]":"22.6","Brain RNA - white matter [nTPM]":"19.7","Single Cell Type RNA - Adipocytes [nTPM]":"201.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"160.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"230.1","Single Cell Type RNA - Astrocytes [nTPM]":"157.4","Single Cell Type RNA - B-cells [nTPM]":"176.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"92.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"112.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"71.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"114.9","Single Cell Type RNA - Bipolar cells [nTPM]":"220.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"87.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"86.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"277.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"60.1","Single Cell Type RNA - Club cells [nTPM]":"101.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"71.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"212.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"72.2","Single Cell Type RNA - dendritic cells [nTPM]":"176.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"49.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"91.8","Single Cell Type RNA - Early spermatids [nTPM]":"4.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"103.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"195.5","Single Cell Type RNA - Endothelial cells [nTPM]":"162.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"126.8","Single Cell Type RNA - Erythroid cells [nTPM]":"105.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"197.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"83.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"51.0","Single Cell Type RNA - Fibroblasts [nTPM]":"134.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"114.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"137.3","Single Cell Type RNA - granulocytes [nTPM]":"113.1","Single Cell Type RNA - Granulosa cells [nTPM]":"261.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"97.8","Single Cell Type RNA - Hepatocytes [nTPM]":"56.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"70.9","Single Cell Type RNA - Horizontal cells [nTPM]":"158.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"246.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"78.0","Single Cell Type RNA - Ionocytes [nTPM]":"69.2","Single Cell Type RNA - Kupffer cells [nTPM]":"87.0","Single Cell Type RNA - Langerhans cells [nTPM]":"101.6","Single Cell Type RNA - Late spermatids [nTPM]":"12.7","Single Cell Type RNA - Leydig cells [nTPM]":"162.4","Single Cell Type RNA - Macrophages [nTPM]":"113.1","Single Cell Type RNA - Melanocytes [nTPM]":"62.2","Single Cell Type RNA - Microglial cells [nTPM]":"195.8","Single Cell Type RNA - monocytes [nTPM]":"149.0","Single Cell Type RNA - Muller glia cells [nTPM]":"112.3","Single Cell Type RNA - NK-cells [nTPM]":"183.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"202.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"237.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"92.0","Single Cell Type RNA - Paneth cells [nTPM]":"47.6","Single Cell Type RNA - Peritubular cells [nTPM]":"208.0","Single Cell Type RNA - Plasma cells [nTPM]":"183.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"120.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"49.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"37.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"102.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"245.4","Single Cell Type RNA - Sertoli cells [nTPM]":"92.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"174.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"160.0","Single Cell Type RNA - Spermatocytes [nTPM]":"19.8","Single Cell Type RNA - Spermatogonia [nTPM]":"52.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"78.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"84.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"59.8","Single Cell Type RNA - T-cells [nTPM]":"158.0","Single Cell Type RNA - Theca cells [nTPM]":"312.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"73.3","Single Cell Type RNA - Urothelial cells [nTPM]":"112.0"},{"Gene":"ATXN3","Gene synonym":["ATX3","JOS","MJD","SCA3"],"Ensembl":"ENSG00000066427","Gene description":"Ataxin 3","Uniprot":["P54252"],"Chromosome":"14","Position":"92044496-92106621","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB021976","HPA024123","HPA069338"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB021976":null,"HPA024123":"AB_1845133","HPA069338":"AB_2686124"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.0","Tissue RNA - adrenal gland [nTPM]":"5.9","Tissue RNA - amygdala [nTPM]":"3.8","Tissue RNA - appendix [nTPM]":"5.7","Tissue RNA - basal ganglia [nTPM]":"4.2","Tissue RNA - bone marrow [nTPM]":"9.9","Tissue RNA - breast [nTPM]":"6.8","Tissue RNA - cerebellum [nTPM]":"4.9","Tissue RNA - cerebral cortex [nTPM]":"5.0","Tissue RNA - cervix [nTPM]":"7.5","Tissue RNA - choroid plexus [nTPM]":"3.3","Tissue RNA - colon [nTPM]":"7.3","Tissue RNA - duodenum [nTPM]":"3.7","Tissue RNA - endometrium 1 [nTPM]":"6.4","Tissue RNA - epididymis [nTPM]":"4.3","Tissue RNA - esophagus [nTPM]":"10.3","Tissue RNA - fallopian tube [nTPM]":"6.0","Tissue RNA - gallbladder [nTPM]":"6.5","Tissue RNA - heart muscle [nTPM]":"5.3","Tissue RNA - hippocampal formation [nTPM]":"3.6","Tissue RNA - hypothalamus [nTPM]":"5.0","Tissue RNA - kidney [nTPM]":"5.6","Tissue RNA - liver [nTPM]":"9.6","Tissue RNA - lung [nTPM]":"6.8","Tissue RNA - lymph node [nTPM]":"7.7","Tissue RNA - medulla oblongata [nTPM]":"6.2","Tissue RNA - midbrain [nTPM]":"5.7","Tissue RNA - ovary [nTPM]":"7.1","Tissue RNA - pancreas [nTPM]":"4.5","Tissue RNA - parathyroid gland [nTPM]":"6.4","Tissue RNA - pituitary gland [nTPM]":"4.0","Tissue RNA - placenta [nTPM]":"7.0","Tissue RNA - pons [nTPM]":"6.2","Tissue RNA - prostate [nTPM]":"6.0","Tissue RNA - rectum [nTPM]":"6.8","Tissue RNA - retina [nTPM]":"3.9","Tissue RNA - salivary gland [nTPM]":"5.8","Tissue RNA - seminal vesicle [nTPM]":"5.5","Tissue RNA - skeletal muscle [nTPM]":"3.3","Tissue RNA - skin 1 [nTPM]":"12.9","Tissue RNA - small intestine [nTPM]":"4.8","Tissue RNA - smooth muscle [nTPM]":"8.6","Tissue RNA - spinal cord [nTPM]":"4.3","Tissue RNA - spleen [nTPM]":"5.6","Tissue RNA - stomach 1 [nTPM]":"5.2","Tissue RNA - testis [nTPM]":"9.3","Tissue RNA - thalamus [nTPM]":"4.3","Tissue RNA - thymus [nTPM]":"8.0","Tissue RNA - thyroid gland [nTPM]":"5.9","Tissue RNA - tongue [nTPM]":"5.9","Tissue RNA - tonsil [nTPM]":"9.8","Tissue RNA - urinary bladder [nTPM]":"9.0","Tissue RNA - vagina [nTPM]":"8.0","Tissue RNA - white matter [nTPM]":"4.9","Cell RNA - A-431 [nTPM]":"8.6","Cell RNA - A549 [nTPM]":"16.7","Cell RNA - AF22 [nTPM]":"14.6","Cell RNA - AN3-CA [nTPM]":"13.6","Cell RNA - ASC diff [nTPM]":"20.9","Cell RNA - ASC TERT1 [nTPM]":"20.1","Cell RNA - BEWO [nTPM]":"28.4","Cell RNA - BJ [nTPM]":"9.7","Cell RNA - BJ hTERT+ [nTPM]":"15.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.5","Cell RNA - CACO-2 [nTPM]":"12.3","Cell RNA - CAPAN-2 [nTPM]":"23.2","Cell RNA - Daudi [nTPM]":"17.6","Cell RNA - EFO-21 [nTPM]":"18.5","Cell RNA - fHDF\/TERT166 [nTPM]":"15.8","Cell RNA - GAMG [nTPM]":"14.1","Cell RNA - HaCaT [nTPM]":"14.6","Cell RNA - HAP1 [nTPM]":"11.6","Cell RNA - HBEC3-KT [nTPM]":"21.0","Cell RNA - HBF TERT88 [nTPM]":"26.3","Cell RNA - HDLM-2 [nTPM]":"20.0","Cell RNA - HEK 293 [nTPM]":"3.5","Cell RNA - HEL [nTPM]":"7.4","Cell RNA - HeLa [nTPM]":"8.0","Cell RNA - Hep G2 [nTPM]":"18.2","Cell RNA - HHSteC [nTPM]":"17.3","Cell RNA - HL-60 [nTPM]":"13.5","Cell RNA - HMC-1 [nTPM]":"12.6","Cell RNA - HSkMC [nTPM]":"16.5","Cell RNA - hTCEpi [nTPM]":"18.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.9","Cell RNA - hTERT-HME1 [nTPM]":"21.8","Cell RNA - hTERT-RPE1 [nTPM]":"15.9","Cell RNA - HUVEC TERT2 [nTPM]":"18.7","Cell RNA - JURKAT [nTPM]":"19.4","Cell RNA - K-562 [nTPM]":"10.1","Cell RNA - Karpas-707 [nTPM]":"12.5","Cell RNA - LHCN-M2 [nTPM]":"18.2","Cell RNA - MCF7 [nTPM]":"33.1","Cell RNA - MOLT-4 [nTPM]":"14.0","Cell RNA - NB-4 [nTPM]":"11.9","Cell RNA - NTERA-2 [nTPM]":"10.4","Cell RNA - OE19 [nTPM]":"28.5","Cell RNA - PC-3 [nTPM]":"13.6","Cell RNA - REH [nTPM]":"11.0","Cell RNA - RH-30 [nTPM]":"27.0","Cell RNA - RPMI-8226 [nTPM]":"9.9","Cell RNA - RPTEC TERT1 [nTPM]":"15.3","Cell RNA - RT4 [nTPM]":"19.4","Cell RNA - SCLC-21H [nTPM]":"5.3","Cell RNA - SH-SY5Y [nTPM]":"8.8","Cell RNA - SiHa [nTPM]":"23.1","Cell RNA - SK-BR-3 [nTPM]":"9.5","Cell RNA - SK-MEL-30 [nTPM]":"13.3","Cell RNA - SuSa [nTPM]":"19.6","Cell RNA - T-47d [nTPM]":"18.1","Cell RNA - THP-1 [nTPM]":"9.1","Cell RNA - TIME [nTPM]":"10.0","Cell RNA - U-138 MG [nTPM]":"11.7","Cell RNA - U-2 OS [nTPM]":"17.0","Cell RNA - U-2197 [nTPM]":"7.5","Cell RNA - U-251 MG [nTPM]":"5.2","Cell RNA - U-266\/70 [nTPM]":"10.8","Cell RNA - U-266\/84 [nTPM]":"19.8","Cell RNA - U-698 [nTPM]":"16.2","Cell RNA - U-87 MG [nTPM]":"8.3","Cell RNA - U-937 [nTPM]":"12.9","Cell RNA - WM-115 [nTPM]":"6.9","Blood RNA - basophil [nTPM]":"13.5","Blood RNA - classical monocyte [nTPM]":"14.3","Blood RNA - eosinophil [nTPM]":"10.8","Blood RNA - gdT-cell [nTPM]":"6.1","Blood RNA - intermediate monocyte [nTPM]":"16.5","Blood RNA - MAIT T-cell [nTPM]":"7.4","Blood RNA - memory B-cell [nTPM]":"7.7","Blood RNA - memory CD4 T-cell [nTPM]":"7.0","Blood RNA - memory CD8 T-cell [nTPM]":"6.9","Blood RNA - myeloid DC [nTPM]":"16.2","Blood RNA - naive B-cell [nTPM]":"10.6","Blood RNA - naive CD4 T-cell [nTPM]":"7.8","Blood RNA - naive CD8 T-cell [nTPM]":"8.8","Blood RNA - neutrophil [nTPM]":"12.2","Blood RNA - NK-cell [nTPM]":"8.7","Blood RNA - non-classical monocyte [nTPM]":"23.0","Blood RNA - plasmacytoid DC [nTPM]":"9.3","Blood RNA - T-reg [nTPM]":"8.1","Blood RNA - total PBMC [nTPM]":"6.3","Brain RNA - amygdala [nTPM]":"3.8","Brain RNA - basal ganglia [nTPM]":"4.2","Brain RNA - cerebellum [nTPM]":"4.9","Brain RNA - cerebral cortex [nTPM]":"5.0","Brain RNA - hippocampal formation [nTPM]":"3.6","Brain RNA - hypothalamus [nTPM]":"5.0","Brain RNA - medulla oblongata [nTPM]":"6.2","Brain RNA - midbrain [nTPM]":"5.7","Brain RNA - pons [nTPM]":"6.2","Brain RNA - spinal cord [nTPM]":"4.3","Brain RNA - thalamus [nTPM]":"4.3","Brain RNA - white matter [nTPM]":"4.9","Single Cell Type RNA - Adipocytes [nTPM]":"55.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.4","Single Cell Type RNA - Astrocytes [nTPM]":"33.6","Single Cell Type RNA - B-cells [nTPM]":"27.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"25.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"28.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.4","Single Cell Type RNA - Bipolar cells [nTPM]":"35.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"20.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"42.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"50.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.3","Single Cell Type RNA - dendritic cells [nTPM]":"31.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"25.8","Single Cell Type RNA - Early spermatids [nTPM]":"19.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"34.9","Single Cell Type RNA - Endothelial cells [nTPM]":"53.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.1","Single Cell Type RNA - Erythroid cells [nTPM]":"30.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"36.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"29.8","Single Cell Type RNA - Fibroblasts [nTPM]":"34.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"22.5","Single Cell Type RNA - granulocytes [nTPM]":"24.6","Single Cell Type RNA - Granulosa cells [nTPM]":"25.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"49.6","Single Cell Type RNA - Hepatocytes [nTPM]":"21.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.4","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"28.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.4","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"35.1","Single Cell Type RNA - Langerhans cells [nTPM]":"27.2","Single Cell Type RNA - Late spermatids [nTPM]":"26.8","Single Cell Type RNA - Leydig cells [nTPM]":"67.7","Single Cell Type RNA - Macrophages [nTPM]":"30.0","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"28.1","Single Cell Type RNA - monocytes [nTPM]":"48.0","Single Cell Type RNA - Muller glia cells [nTPM]":"20.4","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"39.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"51.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.6","Single Cell Type RNA - Paneth cells [nTPM]":"16.1","Single Cell Type RNA - Peritubular cells [nTPM]":"65.1","Single Cell Type RNA - Plasma cells [nTPM]":"20.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"31.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"16.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"46.7","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"51.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"38.2","Single Cell Type RNA - Spermatocytes [nTPM]":"39.1","Single Cell Type RNA - Spermatogonia [nTPM]":"57.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"30.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"25.3","Single Cell Type RNA - T-cells [nTPM]":"28.8","Single Cell Type RNA - Theca cells [nTPM]":"24.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.9","Single Cell Type RNA - Urothelial cells [nTPM]":"28.2"},{"Gene":"AUH","Gene synonym":[],"Ensembl":"ENSG00000148090","Gene description":"AU RNA binding methylglutaconyl-CoA hydratase","Uniprot":["Q13825"],"Chromosome":"9","Position":"91213815-91361918","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Branched-chain amino acid catabolism"],"Molecular function":["Lyase","RNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"191.7","Inhibitory neurons":"137.0","Oligodendrocytes":"137.5","Proximal tubular cells":"120.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"82.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004171"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA004171":"AB_1845215"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Tissue RNA - adipose tissue [nTPM]":"17.2","Tissue RNA - adrenal gland [nTPM]":"41.9","Tissue RNA - amygdala [nTPM]":"11.8","Tissue RNA - appendix [nTPM]":"6.3","Tissue RNA - basal ganglia [nTPM]":"12.3","Tissue RNA - bone marrow [nTPM]":"4.8","Tissue RNA - breast [nTPM]":"15.9","Tissue RNA - cerebellum [nTPM]":"16.0","Tissue RNA - cerebral cortex [nTPM]":"15.3","Tissue RNA - cervix [nTPM]":"13.6","Tissue RNA - choroid plexus [nTPM]":"17.9","Tissue RNA - colon [nTPM]":"17.2","Tissue RNA - duodenum [nTPM]":"23.8","Tissue RNA - endometrium 1 [nTPM]":"10.2","Tissue RNA - epididymis [nTPM]":"14.2","Tissue RNA - esophagus [nTPM]":"8.6","Tissue RNA - fallopian tube [nTPM]":"12.4","Tissue RNA - gallbladder [nTPM]":"10.7","Tissue RNA - heart muscle [nTPM]":"38.9","Tissue RNA - hippocampal formation [nTPM]":"12.1","Tissue RNA - hypothalamus [nTPM]":"14.3","Tissue RNA - kidney [nTPM]":"62.9","Tissue RNA - liver [nTPM]":"26.4","Tissue RNA - lung [nTPM]":"10.3","Tissue RNA - lymph node [nTPM]":"7.6","Tissue RNA - medulla oblongata [nTPM]":"14.8","Tissue RNA - midbrain [nTPM]":"13.6","Tissue RNA - ovary [nTPM]":"13.4","Tissue RNA - pancreas [nTPM]":"25.5","Tissue RNA - parathyroid gland [nTPM]":"45.4","Tissue RNA - pituitary gland [nTPM]":"10.4","Tissue RNA - placenta [nTPM]":"16.1","Tissue RNA - pons [nTPM]":"15.2","Tissue RNA - prostate [nTPM]":"28.2","Tissue RNA - rectum [nTPM]":"17.2","Tissue RNA - retina [nTPM]":"21.4","Tissue RNA - salivary gland [nTPM]":"26.1","Tissue RNA - seminal vesicle [nTPM]":"14.8","Tissue RNA - skeletal muscle [nTPM]":"24.2","Tissue RNA - skin 1 [nTPM]":"8.7","Tissue RNA - small intestine [nTPM]":"20.1","Tissue RNA - smooth muscle [nTPM]":"8.6","Tissue RNA - spinal cord [nTPM]":"12.2","Tissue RNA - spleen [nTPM]":"8.0","Tissue RNA - stomach 1 [nTPM]":"22.7","Tissue RNA - testis [nTPM]":"5.5","Tissue RNA - thalamus [nTPM]":"14.1","Tissue RNA - thymus [nTPM]":"9.0","Tissue RNA - thyroid gland [nTPM]":"21.0","Tissue RNA - tongue [nTPM]":"29.2","Tissue RNA - tonsil [nTPM]":"7.7","Tissue RNA - urinary bladder [nTPM]":"9.1","Tissue RNA - vagina [nTPM]":"9.8","Tissue RNA - white matter [nTPM]":"15.0","Cell RNA - A-431 [nTPM]":"9.1","Cell RNA - A549 [nTPM]":"8.7","Cell RNA - AF22 [nTPM]":"12.0","Cell RNA - AN3-CA [nTPM]":"6.2","Cell RNA - ASC diff [nTPM]":"14.5","Cell RNA - ASC TERT1 [nTPM]":"15.5","Cell RNA - BEWO [nTPM]":"18.5","Cell RNA - BJ [nTPM]":"8.0","Cell RNA - BJ hTERT+ [nTPM]":"10.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.0","Cell RNA - CACO-2 [nTPM]":"5.0","Cell RNA - CAPAN-2 [nTPM]":"11.4","Cell RNA - Daudi [nTPM]":"10.6","Cell RNA - EFO-21 [nTPM]":"8.1","Cell RNA - fHDF\/TERT166 [nTPM]":"8.5","Cell RNA - GAMG [nTPM]":"18.2","Cell RNA - HaCaT [nTPM]":"13.0","Cell RNA - HAP1 [nTPM]":"18.1","Cell RNA - HBEC3-KT [nTPM]":"10.1","Cell RNA - HBF TERT88 [nTPM]":"8.7","Cell RNA - HDLM-2 [nTPM]":"82.6","Cell RNA - HEK 293 [nTPM]":"15.4","Cell RNA - HEL [nTPM]":"7.3","Cell RNA - HeLa [nTPM]":"9.7","Cell RNA - Hep G2 [nTPM]":"29.6","Cell RNA - HHSteC [nTPM]":"11.1","Cell RNA - HL-60 [nTPM]":"10.6","Cell RNA - HMC-1 [nTPM]":"7.3","Cell RNA - HSkMC [nTPM]":"13.1","Cell RNA - hTCEpi [nTPM]":"12.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.9","Cell RNA - hTERT-HME1 [nTPM]":"16.8","Cell RNA - hTERT-RPE1 [nTPM]":"14.3","Cell RNA - HUVEC TERT2 [nTPM]":"7.6","Cell RNA - JURKAT [nTPM]":"10.7","Cell RNA - K-562 [nTPM]":"10.3","Cell RNA - Karpas-707 [nTPM]":"15.5","Cell RNA - LHCN-M2 [nTPM]":"7.2","Cell RNA - MCF7 [nTPM]":"8.8","Cell RNA - MOLT-4 [nTPM]":"14.6","Cell RNA - NB-4 [nTPM]":"23.8","Cell RNA - NTERA-2 [nTPM]":"15.0","Cell RNA - OE19 [nTPM]":"22.2","Cell RNA - PC-3 [nTPM]":"12.5","Cell RNA - REH [nTPM]":"8.5","Cell RNA - RH-30 [nTPM]":"9.6","Cell RNA - RPMI-8226 [nTPM]":"18.6","Cell RNA - RPTEC TERT1 [nTPM]":"26.6","Cell RNA - RT4 [nTPM]":"4.8","Cell RNA - SCLC-21H [nTPM]":"12.2","Cell RNA - SH-SY5Y [nTPM]":"8.8","Cell RNA - SiHa [nTPM]":"11.9","Cell RNA - SK-BR-3 [nTPM]":"28.3","Cell RNA - SK-MEL-30 [nTPM]":"15.6","Cell RNA - SuSa [nTPM]":"27.1","Cell RNA - T-47d [nTPM]":"5.2","Cell RNA - THP-1 [nTPM]":"6.9","Cell RNA - TIME [nTPM]":"7.8","Cell RNA - U-138 MG [nTPM]":"6.1","Cell RNA - U-2 OS [nTPM]":"7.6","Cell RNA - U-2197 [nTPM]":"9.0","Cell RNA - U-251 MG [nTPM]":"7.8","Cell RNA - U-266\/70 [nTPM]":"17.7","Cell RNA - U-266\/84 [nTPM]":"16.1","Cell RNA - U-698 [nTPM]":"3.6","Cell RNA - U-87 MG [nTPM]":"9.6","Cell RNA - U-937 [nTPM]":"8.5","Cell RNA - WM-115 [nTPM]":"4.2","Blood RNA - basophil [nTPM]":"17.9","Blood RNA - classical monocyte [nTPM]":"5.2","Blood RNA - eosinophil [nTPM]":"18.2","Blood RNA - gdT-cell [nTPM]":"7.2","Blood RNA - intermediate monocyte [nTPM]":"3.6","Blood RNA - MAIT T-cell [nTPM]":"8.1","Blood RNA - memory B-cell [nTPM]":"8.4","Blood RNA - memory CD4 T-cell [nTPM]":"7.8","Blood RNA - memory CD8 T-cell [nTPM]":"10.4","Blood RNA - myeloid DC [nTPM]":"4.6","Blood RNA - naive B-cell [nTPM]":"11.8","Blood RNA - naive CD4 T-cell [nTPM]":"9.6","Blood RNA - naive CD8 T-cell [nTPM]":"9.1","Blood RNA - neutrophil [nTPM]":"7.4","Blood RNA - NK-cell [nTPM]":"10.8","Blood RNA - non-classical monocyte [nTPM]":"2.5","Blood RNA - plasmacytoid DC [nTPM]":"6.3","Blood RNA - T-reg [nTPM]":"10.8","Blood RNA - total PBMC [nTPM]":"6.5","Brain RNA - amygdala [nTPM]":"11.8","Brain RNA - basal ganglia [nTPM]":"12.3","Brain RNA - cerebellum [nTPM]":"16.0","Brain RNA - cerebral cortex [nTPM]":"15.3","Brain RNA - hippocampal formation [nTPM]":"12.1","Brain RNA - hypothalamus [nTPM]":"14.3","Brain RNA - medulla oblongata [nTPM]":"14.8","Brain RNA - midbrain [nTPM]":"13.6","Brain RNA - pons [nTPM]":"15.2","Brain RNA - spinal cord [nTPM]":"12.2","Brain RNA - thalamus [nTPM]":"14.1","Brain RNA - white matter [nTPM]":"15.0","Single Cell Type RNA - Adipocytes [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.7","Single Cell Type RNA - Astrocytes [nTPM]":"75.1","Single Cell Type RNA - B-cells [nTPM]":"11.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"27.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Bipolar cells [nTPM]":"18.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"37.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"19.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"44.6","Single Cell Type RNA - dendritic cells [nTPM]":"11.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"27.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"191.7","Single Cell Type RNA - Ductal cells [nTPM]":"29.6","Single Cell Type RNA - Early spermatids [nTPM]":"3.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.1","Single Cell Type RNA - Endothelial cells [nTPM]":"11.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.9","Single Cell Type RNA - Erythroid cells [nTPM]":"28.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"101.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"28.9","Single Cell Type RNA - Fibroblasts [nTPM]":"14.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"14.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"18.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.4","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"137.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.3","Single Cell Type RNA - Ionocytes [nTPM]":"38.7","Single Cell Type RNA - Kupffer cells [nTPM]":"8.9","Single Cell Type RNA - Langerhans cells [nTPM]":"4.7","Single Cell Type RNA - Late spermatids [nTPM]":"1.1","Single Cell Type RNA - Leydig cells [nTPM]":"14.3","Single Cell Type RNA - Macrophages [nTPM]":"8.9","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"67.5","Single Cell Type RNA - monocytes [nTPM]":"29.1","Single Cell Type RNA - Muller glia cells [nTPM]":"9.5","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"100.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"137.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.5","Single Cell Type RNA - Paneth cells [nTPM]":"23.5","Single Cell Type RNA - Peritubular cells [nTPM]":"11.3","Single Cell Type RNA - Plasma cells [nTPM]":"18.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"36.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"59.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"120.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"34.4","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.5","Single Cell Type RNA - Spermatocytes [nTPM]":"8.7","Single Cell Type RNA - Spermatogonia [nTPM]":"10.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"36.4","Single Cell Type RNA - T-cells [nTPM]":"12.9","Single Cell Type RNA - Theca cells [nTPM]":"11.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"25.0","Single Cell Type RNA - Urothelial cells [nTPM]":"24.2"},{"Gene":"AURKB","Gene synonym":["Aik2","AIM-1","ARK2","AurB","IPL1","PPP1R48","STK12","STK5"],"Ensembl":"ENSG00000178999","Gene description":"Aurora kinase B","Uniprot":["Q96GD4"],"Chromosome":"17","Position":"8204733-8210600","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Mitosis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"44.1","lymphoid tissue":"60.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"40.5","Erythroid cells":"59.3","Extravillous trophoblasts":"89.1","Granulosa cells":"24.7","Hofbauer cells":"29.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"7.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"B-cells":"2.5","T-cells":"7.9"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"basal ganglia":"1.3","white matter":"4.0"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005862","HPA037708"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Midbody"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Midbody"],"Antibody RRID":{"CAB005862":"AB_449204","HPA037708":"AB_2675623"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.24e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.1","Tissue RNA - adrenal gland [nTPM]":"1.2","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"14.2","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"44.1","Tissue RNA - breast [nTPM]":"1.7","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"3.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"11.1","Tissue RNA - duodenum [nTPM]":"12.1","Tissue RNA - endometrium 1 [nTPM]":"1.6","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"18.6","Tissue RNA - fallopian tube [nTPM]":"0.6","Tissue RNA - gallbladder [nTPM]":"1.5","Tissue RNA - heart muscle [nTPM]":"0.7","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.9","Tissue RNA - liver [nTPM]":"2.0","Tissue RNA - lung [nTPM]":"2.5","Tissue RNA - lymph node [nTPM]":"36.7","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"0.6","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"8.2","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"0.8","Tissue RNA - rectum [nTPM]":"11.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"2.7","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"5.5","Tissue RNA - skin 1 [nTPM]":"9.3","Tissue RNA - small intestine [nTPM]":"11.6","Tissue RNA - smooth muscle [nTPM]":"3.2","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"12.0","Tissue RNA - stomach 1 [nTPM]":"4.6","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"60.1","Tissue RNA - thyroid gland [nTPM]":"0.6","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"36.6","Tissue RNA - urinary bladder [nTPM]":"3.5","Tissue RNA - vagina [nTPM]":"5.9","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"196.5","Cell RNA - A549 [nTPM]":"130.9","Cell RNA - AF22 [nTPM]":"191.1","Cell RNA - AN3-CA [nTPM]":"93.0","Cell RNA - ASC diff [nTPM]":"4.2","Cell RNA - ASC TERT1 [nTPM]":"6.5","Cell RNA - BEWO [nTPM]":"73.4","Cell RNA - BJ [nTPM]":"91.7","Cell RNA - BJ hTERT+ [nTPM]":"49.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"186.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"170.6","Cell RNA - CACO-2 [nTPM]":"171.5","Cell RNA - CAPAN-2 [nTPM]":"57.4","Cell RNA - Daudi [nTPM]":"193.3","Cell RNA - EFO-21 [nTPM]":"46.2","Cell RNA - fHDF\/TERT166 [nTPM]":"37.0","Cell RNA - GAMG [nTPM]":"77.0","Cell RNA - HaCaT [nTPM]":"139.8","Cell RNA - HAP1 [nTPM]":"140.1","Cell RNA - HBEC3-KT [nTPM]":"62.6","Cell RNA - HBF TERT88 [nTPM]":"153.7","Cell RNA - HDLM-2 [nTPM]":"84.9","Cell RNA - HEK 293 [nTPM]":"231.3","Cell RNA - HEL [nTPM]":"115.7","Cell RNA - HeLa [nTPM]":"78.3","Cell RNA - Hep G2 [nTPM]":"146.1","Cell RNA - HHSteC [nTPM]":"0.7","Cell RNA - HL-60 [nTPM]":"62.2","Cell RNA - HMC-1 [nTPM]":"109.2","Cell RNA - HSkMC [nTPM]":"3.5","Cell RNA - hTCEpi [nTPM]":"2.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"109.4","Cell RNA - hTERT-HME1 [nTPM]":"67.7","Cell RNA - hTERT-RPE1 [nTPM]":"18.5","Cell RNA - HUVEC TERT2 [nTPM]":"86.5","Cell RNA - JURKAT [nTPM]":"123.6","Cell RNA - K-562 [nTPM]":"73.3","Cell RNA - Karpas-707 [nTPM]":"73.4","Cell RNA - LHCN-M2 [nTPM]":"82.9","Cell RNA - MCF7 [nTPM]":"92.9","Cell RNA - MOLT-4 [nTPM]":"225.1","Cell RNA - NB-4 [nTPM]":"87.4","Cell RNA - NTERA-2 [nTPM]":"119.6","Cell RNA - OE19 [nTPM]":"63.9","Cell RNA - PC-3 [nTPM]":"57.6","Cell RNA - REH [nTPM]":"149.8","Cell RNA - RH-30 [nTPM]":"176.1","Cell RNA - RPMI-8226 [nTPM]":"80.5","Cell RNA - RPTEC TERT1 [nTPM]":"41.2","Cell RNA - RT4 [nTPM]":"38.2","Cell RNA - SCLC-21H [nTPM]":"41.2","Cell RNA - SH-SY5Y [nTPM]":"59.1","Cell RNA - SiHa [nTPM]":"81.7","Cell RNA - SK-BR-3 [nTPM]":"36.5","Cell RNA - SK-MEL-30 [nTPM]":"61.2","Cell RNA - SuSa [nTPM]":"56.5","Cell RNA - T-47d [nTPM]":"63.5","Cell RNA - THP-1 [nTPM]":"41.4","Cell RNA - TIME [nTPM]":"33.9","Cell RNA - U-138 MG [nTPM]":"74.3","Cell RNA - U-2 OS [nTPM]":"75.6","Cell RNA - U-2197 [nTPM]":"67.6","Cell RNA - U-251 MG [nTPM]":"243.3","Cell RNA - U-266\/70 [nTPM]":"53.2","Cell RNA - U-266\/84 [nTPM]":"37.7","Cell RNA - U-698 [nTPM]":"147.9","Cell RNA - U-87 MG [nTPM]":"35.7","Cell RNA - U-937 [nTPM]":"92.9","Cell RNA - WM-115 [nTPM]":"153.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"1.1","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"2.1","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"2.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"7.9","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"7.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"40.5","Single Cell Type RNA - dendritic cells [nTPM]":"1.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.6","Single Cell Type RNA - Endothelial cells [nTPM]":"3.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"59.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"89.1","Single Cell Type RNA - Fibroblasts [nTPM]":"5.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.1","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"24.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"29.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"5.7","Single Cell Type RNA - Langerhans cells [nTPM]":"7.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"5.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"2.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"15.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.8","Single Cell Type RNA - Spermatocytes [nTPM]":"1.6","Single Cell Type RNA - Spermatogonia [nTPM]":"7.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.0","Single Cell Type RNA - T-cells [nTPM]":"4.3","Single Cell Type RNA - Theca cells [nTPM]":"1.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"22.0","Single Cell Type RNA - Urothelial cells [nTPM]":"2.8"},{"Gene":"AURKC","Gene synonym":["ARK3","AurC","STK13"],"Ensembl":"ENSG00000105146","Gene description":"Aurora kinase C","Uniprot":["Q9UQB9"],"Chromosome":"19","Position":"57230802-57235548","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Meiosis","Mitosis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"testis":"46.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"150.2","Spermatocytes":"116.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"NTERA-2":"38.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034859"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA034859":"AB_10670298"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-4"},"Tissue RNA - adipose tissue [nTPM]":"1.2","Tissue RNA - adrenal gland [nTPM]":"1.1","Tissue RNA - amygdala [nTPM]":"3.5","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"3.7","Tissue RNA - bone marrow [nTPM]":"1.4","Tissue RNA - breast [nTPM]":"2.0","Tissue RNA - cerebellum [nTPM]":"3.8","Tissue RNA - cerebral cortex [nTPM]":"6.3","Tissue RNA - cervix [nTPM]":"0.7","Tissue RNA - choroid plexus [nTPM]":"3.0","Tissue RNA - colon [nTPM]":"1.0","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"1.3","Tissue RNA - epididymis [nTPM]":"1.8","Tissue RNA - esophagus [nTPM]":"1.0","Tissue RNA - fallopian tube [nTPM]":"1.1","Tissue RNA - gallbladder [nTPM]":"1.4","Tissue RNA - heart muscle [nTPM]":"1.9","Tissue RNA - hippocampal formation [nTPM]":"3.5","Tissue RNA - hypothalamus [nTPM]":"3.5","Tissue RNA - kidney [nTPM]":"1.5","Tissue RNA - liver [nTPM]":"2.7","Tissue RNA - lung [nTPM]":"1.1","Tissue RNA - lymph node [nTPM]":"3.4","Tissue RNA - medulla oblongata [nTPM]":"3.7","Tissue RNA - midbrain [nTPM]":"3.6","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"0.9","Tissue RNA - parathyroid gland [nTPM]":"0.6","Tissue RNA - pituitary gland [nTPM]":"1.4","Tissue RNA - placenta [nTPM]":"1.9","Tissue RNA - pons [nTPM]":"3.9","Tissue RNA - prostate [nTPM]":"0.9","Tissue RNA - rectum [nTPM]":"1.3","Tissue RNA - retina [nTPM]":"1.1","Tissue RNA - salivary gland [nTPM]":"0.8","Tissue RNA - seminal vesicle [nTPM]":"1.4","Tissue RNA - skeletal muscle [nTPM]":"1.9","Tissue RNA - skin 1 [nTPM]":"1.2","Tissue RNA - small intestine [nTPM]":"0.8","Tissue RNA - smooth muscle [nTPM]":"1.1","Tissue RNA - spinal cord [nTPM]":"3.8","Tissue RNA - spleen [nTPM]":"5.0","Tissue RNA - stomach 1 [nTPM]":"0.8","Tissue RNA - testis [nTPM]":"46.9","Tissue RNA - thalamus [nTPM]":"3.7","Tissue RNA - thymus [nTPM]":"1.2","Tissue RNA - thyroid gland [nTPM]":"1.2","Tissue RNA - tongue [nTPM]":"0.5","Tissue RNA - tonsil [nTPM]":"2.2","Tissue RNA - urinary bladder [nTPM]":"1.4","Tissue RNA - vagina [nTPM]":"0.8","Tissue RNA - white matter [nTPM]":"4.3","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.9","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"0.3","Cell RNA - ASC TERT1 [nTPM]":"0.9","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"1.7","Cell RNA - BJ hTERT+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.4","Cell RNA - CACO-2 [nTPM]":"1.3","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.6","Cell RNA - GAMG [nTPM]":"1.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.9","Cell RNA - HBF TERT88 [nTPM]":"0.8","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"4.9","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"1.4","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"1.2","Cell RNA - hTCEpi [nTPM]":"0.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.9","Cell RNA - hTERT-HME1 [nTPM]":"0.7","Cell RNA - hTERT-RPE1 [nTPM]":"1.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.8","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"1.6","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"1.5","Cell RNA - NB-4 [nTPM]":"0.9","Cell RNA - NTERA-2 [nTPM]":"38.4","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"1.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.8","Cell RNA - RPTEC TERT1 [nTPM]":"0.9","Cell RNA - RT4 [nTPM]":"1.7","Cell RNA - SCLC-21H [nTPM]":"1.9","Cell RNA - SH-SY5Y [nTPM]":"0.6","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"1.8","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"5.1","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"1.0","Cell RNA - U-266\/70 [nTPM]":"1.9","Cell RNA - U-266\/84 [nTPM]":"2.7","Cell RNA - U-698 [nTPM]":"0.8","Cell RNA - U-87 MG [nTPM]":"1.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.5","Brain RNA - basal ganglia [nTPM]":"3.7","Brain RNA - cerebellum [nTPM]":"3.8","Brain RNA - cerebral cortex [nTPM]":"6.3","Brain RNA - hippocampal formation [nTPM]":"3.5","Brain RNA - hypothalamus [nTPM]":"3.5","Brain RNA - medulla oblongata [nTPM]":"3.7","Brain RNA - midbrain [nTPM]":"3.6","Brain RNA - pons [nTPM]":"3.9","Brain RNA - spinal cord [nTPM]":"3.8","Brain RNA - thalamus [nTPM]":"3.7","Brain RNA - white matter [nTPM]":"4.3","Single Cell Type RNA - Adipocytes [nTPM]":"1.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"2.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.1","Single Cell Type RNA - Early spermatids [nTPM]":"150.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.9","Single Cell Type RNA - Fibroblasts [nTPM]":"1.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"28.9","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"1.2","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.8","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.3","Single Cell Type RNA - Paneth cells [nTPM]":"1.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"116.8","Single Cell Type RNA - Spermatogonia [nTPM]":"22.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"1.6"},{"Gene":"B2M","Gene synonym":[],"Ensembl":"ENSG00000166710","Gene description":"Beta-2-microglobulin","Uniprot":["P61769"],"Chromosome":"15","Position":"44711487-44718851","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted secreted proteins","Transporters"],"Biological process":["Immunity"],"Molecular function":null,"Disease involvement":["Amyloidosis","Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"monocytes":"31919.3","NK-cells":"24726.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002572","HPA006361"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":1790000000,"Blood concentration - Conc. blood MS [pg\/L]":"2100000000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 3: Monocytes - Immune response regulation","Subcellular main location":["Golgi apparatus","Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB002572":"AB_563434","HPA006361":"AB_1078278"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Tissue RNA - adipose tissue [nTPM]":"3160.2","Tissue RNA - adrenal gland [nTPM]":"3214.7","Tissue RNA - amygdala [nTPM]":"697.6","Tissue RNA - appendix [nTPM]":"5686.5","Tissue RNA - basal ganglia [nTPM]":"705.1","Tissue RNA - bone marrow [nTPM]":"7839.2","Tissue RNA - breast [nTPM]":"2606.9","Tissue RNA - cerebellum [nTPM]":"711.8","Tissue RNA - cerebral cortex [nTPM]":"1145.0","Tissue RNA - cervix [nTPM]":"2539.9","Tissue RNA - choroid plexus [nTPM]":"789.6","Tissue RNA - colon [nTPM]":"5139.0","Tissue RNA - duodenum [nTPM]":"5180.7","Tissue RNA - endometrium 1 [nTPM]":"2192.2","Tissue RNA - epididymis [nTPM]":"1735.6","Tissue RNA - esophagus [nTPM]":"2283.9","Tissue RNA - fallopian tube [nTPM]":"1648.3","Tissue RNA - gallbladder [nTPM]":"4948.8","Tissue RNA - heart muscle [nTPM]":"2327.2","Tissue RNA - hippocampal formation [nTPM]":"651.0","Tissue RNA - hypothalamus [nTPM]":"769.9","Tissue RNA - kidney [nTPM]":"2462.6","Tissue RNA - liver [nTPM]":"6206.2","Tissue RNA - lung [nTPM]":"6159.2","Tissue RNA - lymph node [nTPM]":"9311.8","Tissue RNA - medulla oblongata [nTPM]":"889.5","Tissue RNA - midbrain [nTPM]":"763.2","Tissue RNA - ovary [nTPM]":"1945.7","Tissue RNA - pancreas [nTPM]":"1310.9","Tissue RNA - parathyroid gland [nTPM]":"1940.5","Tissue RNA - pituitary gland [nTPM]":"318.4","Tissue RNA - placenta [nTPM]":"3502.0","Tissue RNA - pons [nTPM]":"815.3","Tissue RNA - prostate [nTPM]":"2345.0","Tissue RNA - rectum [nTPM]":"5593.5","Tissue RNA - retina [nTPM]":"139.3","Tissue RNA - salivary gland [nTPM]":"5657.1","Tissue RNA - seminal vesicle [nTPM]":"1784.5","Tissue RNA - skeletal muscle [nTPM]":"931.7","Tissue RNA - skin 1 [nTPM]":"3015.6","Tissue RNA - small intestine [nTPM]":"5693.3","Tissue RNA - smooth muscle [nTPM]":"2545.3","Tissue RNA - spinal cord [nTPM]":"838.3","Tissue RNA - spleen [nTPM]":"7896.1","Tissue RNA - stomach 1 [nTPM]":"4878.2","Tissue RNA - testis [nTPM]":"615.6","Tissue RNA - thalamus [nTPM]":"771.9","Tissue RNA - thymus [nTPM]":"4217.4","Tissue RNA - thyroid gland [nTPM]":"2340.8","Tissue RNA - tongue [nTPM]":"2026.5","Tissue RNA - tonsil [nTPM]":"5333.4","Tissue RNA - urinary bladder [nTPM]":"5753.1","Tissue RNA - vagina [nTPM]":"549.4","Tissue RNA - white matter [nTPM]":"909.5","Cell RNA - A-431 [nTPM]":"1735.4","Cell RNA - A549 [nTPM]":"378.9","Cell RNA - AF22 [nTPM]":"226.0","Cell RNA - AN3-CA [nTPM]":"633.6","Cell RNA - ASC diff [nTPM]":"4348.7","Cell RNA - ASC TERT1 [nTPM]":"4719.4","Cell RNA - BEWO [nTPM]":"1662.5","Cell RNA - BJ [nTPM]":"2045.5","Cell RNA - BJ hTERT+ [nTPM]":"4961.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3609.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6561.4","Cell RNA - CACO-2 [nTPM]":"425.3","Cell RNA - CAPAN-2 [nTPM]":"5417.9","Cell RNA - Daudi [nTPM]":"554.8","Cell RNA - EFO-21 [nTPM]":"2567.9","Cell RNA - fHDF\/TERT166 [nTPM]":"1948.8","Cell RNA - GAMG [nTPM]":"2410.2","Cell RNA - HaCaT [nTPM]":"2537.0","Cell RNA - HAP1 [nTPM]":"497.2","Cell RNA - HBEC3-KT [nTPM]":"878.7","Cell RNA - HBF TERT88 [nTPM]":"1226.2","Cell RNA - HDLM-2 [nTPM]":"4762.2","Cell RNA - HEK 293 [nTPM]":"435.9","Cell RNA - HEL [nTPM]":"2956.9","Cell RNA - HeLa [nTPM]":"2263.6","Cell RNA - Hep G2 [nTPM]":"600.3","Cell RNA - HHSteC [nTPM]":"3609.3","Cell RNA - HL-60 [nTPM]":"2074.5","Cell RNA - HMC-1 [nTPM]":"3328.6","Cell RNA - HSkMC [nTPM]":"2735.9","Cell RNA - hTCEpi [nTPM]":"609.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1075.7","Cell RNA - hTERT-HME1 [nTPM]":"1044.4","Cell RNA - hTERT-RPE1 [nTPM]":"2442.6","Cell RNA - HUVEC TERT2 [nTPM]":"1884.1","Cell RNA - JURKAT [nTPM]":"965.4","Cell RNA - K-562 [nTPM]":"611.9","Cell RNA - Karpas-707 [nTPM]":"3649.1","Cell RNA - LHCN-M2 [nTPM]":"2195.5","Cell RNA - MCF7 [nTPM]":"476.9","Cell RNA - MOLT-4 [nTPM]":"1518.4","Cell RNA - NB-4 [nTPM]":"3213.8","Cell RNA - NTERA-2 [nTPM]":"206.5","Cell RNA - OE19 [nTPM]":"629.8","Cell RNA - PC-3 [nTPM]":"1014.3","Cell RNA - REH [nTPM]":"2240.2","Cell RNA - RH-30 [nTPM]":"1926.6","Cell RNA - RPMI-8226 [nTPM]":"4789.2","Cell RNA - RPTEC TERT1 [nTPM]":"2425.5","Cell RNA - RT4 [nTPM]":"3486.4","Cell RNA - SCLC-21H [nTPM]":"254.1","Cell RNA - SH-SY5Y [nTPM]":"179.1","Cell RNA - SiHa [nTPM]":"1288.4","Cell RNA - SK-BR-3 [nTPM]":"1571.2","Cell RNA - SK-MEL-30 [nTPM]":"1338.5","Cell RNA - SuSa [nTPM]":"394.3","Cell RNA - T-47d [nTPM]":"655.3","Cell RNA - THP-1 [nTPM]":"6180.6","Cell RNA - TIME [nTPM]":"2548.7","Cell RNA - U-138 MG [nTPM]":"4531.4","Cell RNA - U-2 OS [nTPM]":"676.5","Cell RNA - U-2197 [nTPM]":"5389.2","Cell RNA - U-251 MG [nTPM]":"2193.3","Cell RNA - U-266\/70 [nTPM]":"4771.7","Cell RNA - U-266\/84 [nTPM]":"7118.6","Cell RNA - U-698 [nTPM]":"1683.1","Cell RNA - U-87 MG [nTPM]":"5384.6","Cell RNA - U-937 [nTPM]":"3783.6","Cell RNA - WM-115 [nTPM]":"2567.3","Blood RNA - basophil [nTPM]":"48105.4","Blood RNA - classical monocyte [nTPM]":"18117.1","Blood RNA - eosinophil [nTPM]":"33178.9","Blood RNA - gdT-cell [nTPM]":"20639.1","Blood RNA - intermediate monocyte [nTPM]":"17775.0","Blood RNA - MAIT T-cell [nTPM]":"20836.8","Blood RNA - memory B-cell [nTPM]":"15768.0","Blood RNA - memory CD4 T-cell [nTPM]":"23783.0","Blood RNA - memory CD8 T-cell [nTPM]":"22245.1","Blood RNA - myeloid DC [nTPM]":"9978.8","Blood RNA - naive B-cell [nTPM]":"11988.4","Blood RNA - naive CD4 T-cell [nTPM]":"17122.9","Blood RNA - naive CD8 T-cell [nTPM]":"22791.8","Blood RNA - neutrophil [nTPM]":"50453.6","Blood RNA - NK-cell [nTPM]":"18779.6","Blood RNA - non-classical monocyte [nTPM]":"19034.9","Blood RNA - plasmacytoid DC [nTPM]":"12052.6","Blood RNA - T-reg [nTPM]":"29659.1","Blood RNA - total PBMC [nTPM]":"56957.2","Brain RNA - amygdala [nTPM]":"697.6","Brain RNA - basal ganglia [nTPM]":"705.1","Brain RNA - cerebellum [nTPM]":"711.8","Brain RNA - cerebral cortex [nTPM]":"1145.0","Brain RNA - hippocampal formation [nTPM]":"651.0","Brain RNA - hypothalamus [nTPM]":"769.9","Brain RNA - medulla oblongata [nTPM]":"889.5","Brain RNA - midbrain [nTPM]":"763.2","Brain RNA - pons [nTPM]":"815.3","Brain RNA - spinal cord [nTPM]":"838.3","Brain RNA - thalamus [nTPM]":"771.9","Brain RNA - white matter [nTPM]":"909.5","Single Cell Type RNA - Adipocytes [nTPM]":"12048.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3387.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3505.1","Single Cell Type RNA - Astrocytes [nTPM]":"28.7","Single Cell Type RNA - B-cells [nTPM]":"8472.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7843.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3197.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8420.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1628.8","Single Cell Type RNA - Bipolar cells [nTPM]":"33.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"2399.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2015.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1068.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"3593.1","Single Cell Type RNA - Club cells [nTPM]":"5347.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"2100.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1354.6","Single Cell Type RNA - dendritic cells [nTPM]":"14028.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"8753.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1038.9","Single Cell Type RNA - Ductal cells [nTPM]":"13898.6","Single Cell Type RNA - Early spermatids [nTPM]":"43.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2073.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2414.0","Single Cell Type RNA - Endothelial cells [nTPM]":"8385.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2266.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2087.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9034.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4397.5","Single Cell Type RNA - Fibroblasts [nTPM]":"3691.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1981.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2282.2","Single Cell Type RNA - granulocytes [nTPM]":"3029.5","Single Cell Type RNA - Granulosa cells [nTPM]":"1270.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6835.7","Single Cell Type RNA - Hepatocytes [nTPM]":"3832.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"11985.7","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5982.6","Single Cell Type RNA - Ionocytes [nTPM]":"8701.4","Single Cell Type RNA - Kupffer cells [nTPM]":"12536.8","Single Cell Type RNA - Langerhans cells [nTPM]":"14507.0","Single Cell Type RNA - Late spermatids [nTPM]":"158.8","Single Cell Type RNA - Leydig cells [nTPM]":"3018.0","Single Cell Type RNA - Macrophages [nTPM]":"10687.9","Single Cell Type RNA - Melanocytes [nTPM]":"6744.8","Single Cell Type RNA - Microglial cells [nTPM]":"368.2","Single Cell Type RNA - monocytes [nTPM]":"31919.3","Single Cell Type RNA - Muller glia cells [nTPM]":"322.0","Single Cell Type RNA - NK-cells [nTPM]":"24726.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"95.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"129.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10115.7","Single Cell Type RNA - Paneth cells [nTPM]":"7085.6","Single Cell Type RNA - Peritubular cells [nTPM]":"1688.8","Single Cell Type RNA - Plasma cells [nTPM]":"11026.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5300.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18327.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3122.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8367.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"52.5","Single Cell Type RNA - Sertoli cells [nTPM]":"4016.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2055.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4107.1","Single Cell Type RNA - Spermatocytes [nTPM]":"64.2","Single Cell Type RNA - Spermatogonia [nTPM]":"72.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1541.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8619.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"804.8","Single Cell Type RNA - T-cells [nTPM]":"14266.2","Single Cell Type RNA - Theca cells [nTPM]":"3229.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3063.4","Single Cell Type RNA - Urothelial cells [nTPM]":"8248.6"},{"Gene":"B3GALNT2","Gene synonym":["MGC39558"],"Ensembl":"ENSG00000162885","Gene description":"Beta-1,3-N-acetylgalactosaminyltransferase 2","Uniprot":["Q8NCR0"],"Chromosome":"1","Position":"235447190-235504452","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital muscular dystrophy","Disease variant","Dystroglycanopathy","Lissencephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"252.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007846","HPA050662"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA007846":null,"HPA050662":"AB_2681209"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-3"},"Tissue RNA - adipose tissue [nTPM]":"4.7","Tissue RNA - adrenal gland [nTPM]":"5.4","Tissue RNA - amygdala [nTPM]":"2.3","Tissue RNA - appendix [nTPM]":"2.8","Tissue RNA - basal ganglia [nTPM]":"2.2","Tissue RNA - bone marrow [nTPM]":"1.6","Tissue RNA - breast [nTPM]":"4.0","Tissue RNA - cerebellum [nTPM]":"2.5","Tissue RNA - cerebral cortex [nTPM]":"2.4","Tissue RNA - cervix [nTPM]":"5.3","Tissue RNA - choroid plexus [nTPM]":"5.7","Tissue RNA - colon [nTPM]":"8.1","Tissue RNA - duodenum [nTPM]":"3.2","Tissue RNA - endometrium 1 [nTPM]":"7.3","Tissue RNA - epididymis [nTPM]":"4.8","Tissue RNA - esophagus [nTPM]":"8.9","Tissue RNA - fallopian tube [nTPM]":"5.5","Tissue RNA - gallbladder [nTPM]":"5.3","Tissue RNA - heart muscle [nTPM]":"6.1","Tissue RNA - hippocampal formation [nTPM]":"2.4","Tissue RNA - hypothalamus [nTPM]":"2.6","Tissue RNA - kidney [nTPM]":"3.3","Tissue RNA - liver [nTPM]":"3.2","Tissue RNA - lung [nTPM]":"3.4","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"2.4","Tissue RNA - midbrain [nTPM]":"2.7","Tissue RNA - ovary [nTPM]":"5.1","Tissue RNA - pancreas [nTPM]":"22.3","Tissue RNA - parathyroid gland [nTPM]":"6.7","Tissue RNA - pituitary gland [nTPM]":"3.8","Tissue RNA - placenta [nTPM]":"4.3","Tissue RNA - pons [nTPM]":"2.3","Tissue RNA - prostate [nTPM]":"7.3","Tissue RNA - rectum [nTPM]":"5.3","Tissue RNA - retina [nTPM]":"3.9","Tissue RNA - salivary gland [nTPM]":"6.0","Tissue RNA - seminal vesicle [nTPM]":"6.6","Tissue RNA - skeletal muscle [nTPM]":"23.3","Tissue RNA - skin 1 [nTPM]":"6.2","Tissue RNA - small intestine [nTPM]":"5.1","Tissue RNA - smooth muscle [nTPM]":"10.6","Tissue RNA - spinal cord [nTPM]":"2.3","Tissue RNA - spleen [nTPM]":"2.7","Tissue RNA - stomach 1 [nTPM]":"8.9","Tissue RNA - testis [nTPM]":"5.9","Tissue RNA - thalamus [nTPM]":"2.5","Tissue RNA - thymus [nTPM]":"3.6","Tissue RNA - thyroid gland [nTPM]":"7.3","Tissue RNA - tongue [nTPM]":"16.7","Tissue RNA - tonsil [nTPM]":"3.4","Tissue RNA - urinary bladder [nTPM]":"7.9","Tissue RNA - vagina [nTPM]":"5.4","Tissue RNA - white matter [nTPM]":"2.2","Cell RNA - A-431 [nTPM]":"15.0","Cell RNA - A549 [nTPM]":"10.4","Cell RNA - AF22 [nTPM]":"11.1","Cell RNA - AN3-CA [nTPM]":"16.2","Cell RNA - ASC diff [nTPM]":"14.2","Cell RNA - ASC TERT1 [nTPM]":"15.7","Cell RNA - BEWO [nTPM]":"21.6","Cell RNA - BJ [nTPM]":"14.1","Cell RNA - BJ hTERT+ [nTPM]":"11.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.0","Cell RNA - CACO-2 [nTPM]":"7.7","Cell RNA - CAPAN-2 [nTPM]":"13.1","Cell RNA - Daudi [nTPM]":"8.2","Cell RNA - EFO-21 [nTPM]":"15.3","Cell RNA - fHDF\/TERT166 [nTPM]":"15.5","Cell RNA - GAMG [nTPM]":"7.0","Cell RNA - HaCaT [nTPM]":"17.3","Cell RNA - HAP1 [nTPM]":"21.3","Cell RNA - HBEC3-KT [nTPM]":"14.8","Cell RNA - HBF TERT88 [nTPM]":"12.5","Cell RNA - HDLM-2 [nTPM]":"14.5","Cell RNA - HEK 293 [nTPM]":"11.7","Cell RNA - HEL [nTPM]":"5.8","Cell RNA - HeLa [nTPM]":"12.7","Cell RNA - Hep G2 [nTPM]":"9.3","Cell RNA - HHSteC [nTPM]":"10.0","Cell RNA - HL-60 [nTPM]":"17.9","Cell RNA - HMC-1 [nTPM]":"4.3","Cell RNA - HSkMC [nTPM]":"9.9","Cell RNA - hTCEpi [nTPM]":"9.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.4","Cell RNA - hTERT-HME1 [nTPM]":"21.5","Cell RNA - hTERT-RPE1 [nTPM]":"7.0","Cell RNA - HUVEC TERT2 [nTPM]":"14.1","Cell RNA - JURKAT [nTPM]":"19.2","Cell RNA - K-562 [nTPM]":"10.9","Cell RNA - Karpas-707 [nTPM]":"10.9","Cell RNA - LHCN-M2 [nTPM]":"9.2","Cell RNA - MCF7 [nTPM]":"7.3","Cell RNA - MOLT-4 [nTPM]":"10.0","Cell RNA - NB-4 [nTPM]":"8.8","Cell RNA - NTERA-2 [nTPM]":"15.7","Cell RNA - OE19 [nTPM]":"7.9","Cell RNA - PC-3 [nTPM]":"3.1","Cell RNA - REH [nTPM]":"10.6","Cell RNA - RH-30 [nTPM]":"19.9","Cell RNA - RPMI-8226 [nTPM]":"18.8","Cell RNA - RPTEC TERT1 [nTPM]":"6.4","Cell RNA - RT4 [nTPM]":"21.1","Cell RNA - SCLC-21H [nTPM]":"14.2","Cell RNA - SH-SY5Y [nTPM]":"16.8","Cell RNA - SiHa [nTPM]":"23.7","Cell RNA - SK-BR-3 [nTPM]":"7.8","Cell RNA - SK-MEL-30 [nTPM]":"12.2","Cell RNA - SuSa [nTPM]":"3.9","Cell RNA - T-47d [nTPM]":"18.5","Cell RNA - THP-1 [nTPM]":"15.6","Cell RNA - TIME [nTPM]":"13.1","Cell RNA - U-138 MG [nTPM]":"9.7","Cell RNA - U-2 OS [nTPM]":"13.3","Cell RNA - U-2197 [nTPM]":"16.6","Cell RNA - U-251 MG [nTPM]":"18.1","Cell RNA - U-266\/70 [nTPM]":"11.3","Cell RNA - U-266\/84 [nTPM]":"14.8","Cell RNA - U-698 [nTPM]":"5.0","Cell RNA - U-87 MG [nTPM]":"6.7","Cell RNA - U-937 [nTPM]":"12.1","Cell RNA - WM-115 [nTPM]":"21.7","Blood RNA - basophil [nTPM]":"1.1","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"1.6","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"2.3","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"1.2","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"1.9","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"2.3","Brain RNA - basal ganglia [nTPM]":"2.2","Brain RNA - cerebellum [nTPM]":"2.5","Brain RNA - cerebral cortex [nTPM]":"2.4","Brain RNA - hippocampal formation [nTPM]":"2.4","Brain RNA - hypothalamus [nTPM]":"2.6","Brain RNA - medulla oblongata [nTPM]":"2.4","Brain RNA - midbrain [nTPM]":"2.7","Brain RNA - pons [nTPM]":"2.3","Brain RNA - spinal cord [nTPM]":"2.3","Brain RNA - thalamus [nTPM]":"2.5","Brain RNA - white matter [nTPM]":"2.2","Single Cell Type RNA - Adipocytes [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.0","Single Cell Type RNA - Astrocytes [nTPM]":"38.8","Single Cell Type RNA - B-cells [nTPM]":"7.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"31.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"39.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"36.5","Single Cell Type RNA - Bipolar cells [nTPM]":"33.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"9.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"252.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.3","Single Cell Type RNA - dendritic cells [nTPM]":"14.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.9","Single Cell Type RNA - Early spermatids [nTPM]":"26.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.8","Single Cell Type RNA - Endothelial cells [nTPM]":"7.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"38.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.0","Single Cell Type RNA - Fibroblasts [nTPM]":"11.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.9","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"11.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.6","Single Cell Type RNA - Hepatocytes [nTPM]":"4.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.9","Single Cell Type RNA - Horizontal cells [nTPM]":"28.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"56.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.2","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"3.0","Single Cell Type RNA - Langerhans cells [nTPM]":"16.3","Single Cell Type RNA - Late spermatids [nTPM]":"7.3","Single Cell Type RNA - Leydig cells [nTPM]":"10.5","Single Cell Type RNA - Macrophages [nTPM]":"6.9","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"11.5","Single Cell Type RNA - Muller glia cells [nTPM]":"11.2","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"29.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.2","Single Cell Type RNA - Paneth cells [nTPM]":"5.4","Single Cell Type RNA - Peritubular cells [nTPM]":"16.1","Single Cell Type RNA - Plasma cells [nTPM]":"14.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"27.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.5","Single Cell Type RNA - Spermatocytes [nTPM]":"35.8","Single Cell Type RNA - Spermatogonia [nTPM]":"40.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"29.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.4","Single Cell Type RNA - T-cells [nTPM]":"9.0","Single Cell Type RNA - Theca cells [nTPM]":"17.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.0","Single Cell Type RNA - Urothelial cells [nTPM]":"33.1"},{"Gene":"B3GALT6","Gene synonym":["beta3GalT6"],"Ensembl":"ENSG00000176022","Gene description":"Beta-1,3-galactosyltransferase 6","Uniprot":["Q96L58"],"Chromosome":"1","Position":"1232237-1235041","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant","Dwarfism","Ehlers-Danlos syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SCLC-21H":"69.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"14000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.7","Tissue RNA - adrenal gland [nTPM]":"8.7","Tissue RNA - amygdala [nTPM]":"8.9","Tissue RNA - appendix [nTPM]":"5.6","Tissue RNA - basal ganglia [nTPM]":"9.0","Tissue RNA - bone marrow [nTPM]":"1.8","Tissue RNA - breast [nTPM]":"8.4","Tissue RNA - cerebellum [nTPM]":"7.3","Tissue RNA - cerebral cortex [nTPM]":"9.9","Tissue RNA - cervix [nTPM]":"7.6","Tissue RNA - choroid plexus [nTPM]":"7.3","Tissue RNA - colon [nTPM]":"6.5","Tissue RNA - duodenum [nTPM]":"3.9","Tissue RNA - endometrium 1 [nTPM]":"10.7","Tissue RNA - epididymis [nTPM]":"3.8","Tissue RNA - esophagus [nTPM]":"7.2","Tissue RNA - fallopian tube [nTPM]":"7.7","Tissue RNA - gallbladder [nTPM]":"3.7","Tissue RNA - heart muscle [nTPM]":"10.1","Tissue RNA - hippocampal formation [nTPM]":"9.5","Tissue RNA - hypothalamus [nTPM]":"10.1","Tissue RNA - kidney [nTPM]":"9.9","Tissue RNA - liver [nTPM]":"13.5","Tissue RNA - lung [nTPM]":"6.8","Tissue RNA - lymph node [nTPM]":"6.2","Tissue RNA - medulla oblongata [nTPM]":"10.4","Tissue RNA - midbrain [nTPM]":"9.3","Tissue RNA - ovary [nTPM]":"7.0","Tissue RNA - pancreas [nTPM]":"11.9","Tissue RNA - parathyroid gland [nTPM]":"7.8","Tissue RNA - pituitary gland [nTPM]":"9.3","Tissue RNA - placenta [nTPM]":"5.2","Tissue RNA - pons [nTPM]":"8.8","Tissue RNA - prostate [nTPM]":"8.0","Tissue RNA - rectum [nTPM]":"3.0","Tissue RNA - retina [nTPM]":"2.4","Tissue RNA - salivary gland [nTPM]":"6.4","Tissue RNA - seminal vesicle [nTPM]":"4.2","Tissue RNA - skeletal muscle [nTPM]":"9.3","Tissue RNA - skin 1 [nTPM]":"9.2","Tissue RNA - small intestine [nTPM]":"6.5","Tissue RNA - smooth muscle [nTPM]":"4.8","Tissue RNA - spinal cord [nTPM]":"8.3","Tissue RNA - spleen [nTPM]":"10.3","Tissue RNA - stomach 1 [nTPM]":"7.8","Tissue RNA - testis [nTPM]":"5.4","Tissue RNA - thalamus [nTPM]":"9.0","Tissue RNA - thymus [nTPM]":"5.8","Tissue RNA - thyroid gland [nTPM]":"7.7","Tissue RNA - tongue [nTPM]":"4.8","Tissue RNA - tonsil [nTPM]":"3.7","Tissue RNA - urinary bladder [nTPM]":"7.6","Tissue RNA - vagina [nTPM]":"6.3","Tissue RNA - white matter [nTPM]":"9.3","Cell RNA - A-431 [nTPM]":"20.4","Cell RNA - A549 [nTPM]":"10.2","Cell RNA - AF22 [nTPM]":"17.0","Cell RNA - AN3-CA [nTPM]":"17.9","Cell RNA - ASC diff [nTPM]":"16.8","Cell RNA - ASC TERT1 [nTPM]":"11.3","Cell RNA - BEWO [nTPM]":"13.2","Cell RNA - BJ [nTPM]":"21.2","Cell RNA - BJ hTERT+ [nTPM]":"17.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.1","Cell RNA - CACO-2 [nTPM]":"9.1","Cell RNA - CAPAN-2 [nTPM]":"20.3","Cell RNA - Daudi [nTPM]":"15.1","Cell RNA - EFO-21 [nTPM]":"12.4","Cell RNA - fHDF\/TERT166 [nTPM]":"12.7","Cell RNA - GAMG [nTPM]":"15.2","Cell RNA - HaCaT [nTPM]":"17.9","Cell RNA - HAP1 [nTPM]":"7.4","Cell RNA - HBEC3-KT [nTPM]":"11.4","Cell RNA - HBF TERT88 [nTPM]":"10.6","Cell RNA - HDLM-2 [nTPM]":"26.8","Cell RNA - HEK 293 [nTPM]":"28.2","Cell RNA - HEL [nTPM]":"28.2","Cell RNA - HeLa [nTPM]":"10.1","Cell RNA - Hep G2 [nTPM]":"8.7","Cell RNA - HHSteC [nTPM]":"17.3","Cell RNA - HL-60 [nTPM]":"17.6","Cell RNA - HMC-1 [nTPM]":"17.1","Cell RNA - HSkMC [nTPM]":"10.6","Cell RNA - hTCEpi [nTPM]":"8.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.6","Cell RNA - hTERT-HME1 [nTPM]":"11.3","Cell RNA - hTERT-RPE1 [nTPM]":"10.5","Cell RNA - HUVEC TERT2 [nTPM]":"13.3","Cell RNA - JURKAT [nTPM]":"17.2","Cell RNA - K-562 [nTPM]":"20.0","Cell RNA - Karpas-707 [nTPM]":"13.2","Cell RNA - LHCN-M2 [nTPM]":"18.0","Cell RNA - MCF7 [nTPM]":"11.6","Cell RNA - MOLT-4 [nTPM]":"24.0","Cell RNA - NB-4 [nTPM]":"31.6","Cell RNA - NTERA-2 [nTPM]":"21.9","Cell RNA - OE19 [nTPM]":"21.2","Cell RNA - PC-3 [nTPM]":"37.9","Cell RNA - REH [nTPM]":"22.8","Cell RNA - RH-30 [nTPM]":"6.7","Cell RNA - RPMI-8226 [nTPM]":"12.5","Cell RNA - RPTEC TERT1 [nTPM]":"17.4","Cell RNA - RT4 [nTPM]":"6.1","Cell RNA - SCLC-21H [nTPM]":"69.6","Cell RNA - SH-SY5Y [nTPM]":"28.6","Cell RNA - SiHa [nTPM]":"15.8","Cell RNA - SK-BR-3 [nTPM]":"18.4","Cell RNA - SK-MEL-30 [nTPM]":"11.4","Cell RNA - SuSa [nTPM]":"9.9","Cell RNA - T-47d [nTPM]":"15.4","Cell RNA - THP-1 [nTPM]":"24.9","Cell RNA - TIME [nTPM]":"14.4","Cell RNA - U-138 MG [nTPM]":"17.9","Cell RNA - U-2 OS [nTPM]":"7.9","Cell RNA - U-2197 [nTPM]":"11.3","Cell RNA - U-251 MG [nTPM]":"30.9","Cell RNA - U-266\/70 [nTPM]":"8.2","Cell RNA - U-266\/84 [nTPM]":"7.6","Cell RNA - U-698 [nTPM]":"14.0","Cell RNA - U-87 MG [nTPM]":"14.1","Cell RNA - U-937 [nTPM]":"38.9","Cell RNA - WM-115 [nTPM]":"20.8","Blood RNA - basophil [nTPM]":"1.3","Blood RNA - classical monocyte [nTPM]":"1.2","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"1.6","Blood RNA - MAIT T-cell [nTPM]":"2.8","Blood RNA - memory B-cell [nTPM]":"1.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.6","Blood RNA - memory CD8 T-cell [nTPM]":"1.9","Blood RNA - myeloid DC [nTPM]":"1.7","Blood RNA - naive B-cell [nTPM]":"2.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.4","Blood RNA - naive CD8 T-cell [nTPM]":"1.7","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"2.9","Blood RNA - non-classical monocyte [nTPM]":"2.0","Blood RNA - plasmacytoid DC [nTPM]":"2.3","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"8.9","Brain RNA - basal ganglia [nTPM]":"9.0","Brain RNA - cerebellum [nTPM]":"7.3","Brain RNA - cerebral cortex [nTPM]":"9.9","Brain RNA - hippocampal formation [nTPM]":"9.5","Brain RNA - hypothalamus [nTPM]":"10.1","Brain RNA - medulla oblongata [nTPM]":"10.4","Brain RNA - midbrain [nTPM]":"9.3","Brain RNA - pons [nTPM]":"8.8","Brain RNA - spinal cord [nTPM]":"8.3","Brain RNA - thalamus [nTPM]":"9.0","Brain RNA - white matter [nTPM]":"9.3","Single Cell Type RNA - Adipocytes [nTPM]":"15.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.9","Single Cell Type RNA - Astrocytes [nTPM]":"3.9","Single Cell Type RNA - B-cells [nTPM]":"13.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"31.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"13.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"3.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.7","Single Cell Type RNA - dendritic cells [nTPM]":"20.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.0","Single Cell Type RNA - Endothelial cells [nTPM]":"12.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.4","Single Cell Type RNA - Fibroblasts [nTPM]":"10.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"24.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.4","Single Cell Type RNA - Hepatocytes [nTPM]":"13.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.3","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.7","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"12.2","Single Cell Type RNA - Langerhans cells [nTPM]":"10.3","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"10.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"6.9","Single Cell Type RNA - Muller glia cells [nTPM]":"11.0","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.9","Single Cell Type RNA - Paneth cells [nTPM]":"1.0","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"9.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"24.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.8","Single Cell Type RNA - Spermatocytes [nTPM]":"1.7","Single Cell Type RNA - Spermatogonia [nTPM]":"4.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - T-cells [nTPM]":"11.1","Single Cell Type RNA - Theca cells [nTPM]":"33.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.3","Single Cell Type RNA - Urothelial cells [nTPM]":"14.8"},{"Gene":"B3GAT3","Gene synonym":["GlcAT-I"],"Ensembl":"ENSG00000149541","Gene description":"Beta-1,3-glucuronyltransferase 3","Uniprot":["O94766"],"Chromosome":"11","Position":"62615296-62622154","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051328"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"990000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051328":"AB_2681444"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.69e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.11e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Tissue RNA - adipose tissue [nTPM]":"28.2","Tissue RNA - adrenal gland [nTPM]":"30.0","Tissue RNA - amygdala [nTPM]":"63.4","Tissue RNA - appendix [nTPM]":"17.0","Tissue RNA - basal ganglia [nTPM]":"63.8","Tissue RNA - bone marrow [nTPM]":"18.2","Tissue RNA - breast [nTPM]":"27.4","Tissue RNA - cerebellum [nTPM]":"67.0","Tissue RNA - cerebral cortex [nTPM]":"81.8","Tissue RNA - cervix [nTPM]":"33.7","Tissue RNA - choroid plexus [nTPM]":"65.9","Tissue RNA - colon [nTPM]":"27.8","Tissue RNA - duodenum [nTPM]":"17.2","Tissue RNA - endometrium 1 [nTPM]":"30.0","Tissue RNA - epididymis [nTPM]":"11.5","Tissue RNA - esophagus [nTPM]":"21.0","Tissue RNA - fallopian tube [nTPM]":"30.0","Tissue RNA - gallbladder [nTPM]":"15.3","Tissue RNA - heart muscle [nTPM]":"23.1","Tissue RNA - hippocampal formation [nTPM]":"64.0","Tissue RNA - hypothalamus [nTPM]":"66.7","Tissue RNA - kidney [nTPM]":"52.1","Tissue RNA - liver [nTPM]":"48.7","Tissue RNA - lung [nTPM]":"29.0","Tissue RNA - lymph node [nTPM]":"26.2","Tissue RNA - medulla oblongata [nTPM]":"72.3","Tissue RNA - midbrain [nTPM]":"64.3","Tissue RNA - ovary [nTPM]":"32.3","Tissue RNA - pancreas [nTPM]":"30.7","Tissue RNA - parathyroid gland [nTPM]":"19.1","Tissue RNA - pituitary gland [nTPM]":"55.7","Tissue RNA - placenta [nTPM]":"19.1","Tissue RNA - pons [nTPM]":"76.5","Tissue RNA - prostate [nTPM]":"37.1","Tissue RNA - rectum [nTPM]":"6.9","Tissue RNA - retina [nTPM]":"16.0","Tissue RNA - salivary gland [nTPM]":"25.9","Tissue RNA - seminal vesicle [nTPM]":"18.2","Tissue RNA - skeletal muscle [nTPM]":"14.3","Tissue RNA - skin 1 [nTPM]":"33.9","Tissue RNA - small intestine [nTPM]":"27.8","Tissue RNA - smooth muscle [nTPM]":"14.0","Tissue RNA - spinal cord [nTPM]":"63.3","Tissue RNA - spleen [nTPM]":"40.0","Tissue RNA - stomach 1 [nTPM]":"28.9","Tissue RNA - testis [nTPM]":"23.9","Tissue RNA - thalamus [nTPM]":"67.1","Tissue RNA - thymus [nTPM]":"18.5","Tissue RNA - thyroid gland [nTPM]":"30.1","Tissue RNA - tongue [nTPM]":"6.8","Tissue RNA - tonsil [nTPM]":"10.8","Tissue RNA - urinary bladder [nTPM]":"30.5","Tissue RNA - vagina [nTPM]":"25.7","Tissue RNA - white matter [nTPM]":"69.7","Cell RNA - A-431 [nTPM]":"36.0","Cell RNA - A549 [nTPM]":"57.3","Cell RNA - AF22 [nTPM]":"32.0","Cell RNA - AN3-CA [nTPM]":"55.0","Cell RNA - ASC diff [nTPM]":"40.0","Cell RNA - ASC TERT1 [nTPM]":"38.7","Cell RNA - BEWO [nTPM]":"23.4","Cell RNA - BJ [nTPM]":"28.3","Cell RNA - BJ hTERT+ [nTPM]":"38.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"26.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"29.4","Cell RNA - CACO-2 [nTPM]":"25.4","Cell RNA - CAPAN-2 [nTPM]":"52.3","Cell RNA - Daudi [nTPM]":"33.4","Cell RNA - EFO-21 [nTPM]":"91.1","Cell RNA - fHDF\/TERT166 [nTPM]":"29.5","Cell RNA - GAMG [nTPM]":"70.6","Cell RNA - HaCaT [nTPM]":"24.5","Cell RNA - HAP1 [nTPM]":"30.8","Cell RNA - HBEC3-KT [nTPM]":"28.7","Cell RNA - HBF TERT88 [nTPM]":"6.2","Cell RNA - HDLM-2 [nTPM]":"71.5","Cell RNA - HEK 293 [nTPM]":"61.3","Cell RNA - HEL [nTPM]":"17.0","Cell RNA - HeLa [nTPM]":"25.9","Cell RNA - Hep G2 [nTPM]":"32.8","Cell RNA - HHSteC [nTPM]":"96.8","Cell RNA - HL-60 [nTPM]":"21.4","Cell RNA - HMC-1 [nTPM]":"34.8","Cell RNA - HSkMC [nTPM]":"69.1","Cell RNA - hTCEpi [nTPM]":"47.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"35.0","Cell RNA - hTERT-HME1 [nTPM]":"15.3","Cell RNA - hTERT-RPE1 [nTPM]":"42.4","Cell RNA - HUVEC TERT2 [nTPM]":"25.3","Cell RNA - JURKAT [nTPM]":"37.9","Cell RNA - K-562 [nTPM]":"51.5","Cell RNA - Karpas-707 [nTPM]":"76.7","Cell RNA - LHCN-M2 [nTPM]":"33.9","Cell RNA - MCF7 [nTPM]":"89.1","Cell RNA - MOLT-4 [nTPM]":"38.1","Cell RNA - NB-4 [nTPM]":"76.7","Cell RNA - NTERA-2 [nTPM]":"47.5","Cell RNA - OE19 [nTPM]":"18.9","Cell RNA - PC-3 [nTPM]":"55.1","Cell RNA - REH [nTPM]":"36.7","Cell RNA - RH-30 [nTPM]":"22.5","Cell RNA - RPMI-8226 [nTPM]":"175.4","Cell RNA - RPTEC TERT1 [nTPM]":"55.0","Cell RNA - RT4 [nTPM]":"7.2","Cell RNA - SCLC-21H [nTPM]":"33.6","Cell RNA - SH-SY5Y [nTPM]":"53.1","Cell RNA - SiHa [nTPM]":"32.6","Cell RNA - SK-BR-3 [nTPM]":"38.2","Cell RNA - SK-MEL-30 [nTPM]":"134.6","Cell RNA - SuSa [nTPM]":"10.6","Cell RNA - T-47d [nTPM]":"52.9","Cell RNA - THP-1 [nTPM]":"41.6","Cell RNA - TIME [nTPM]":"18.6","Cell RNA - U-138 MG [nTPM]":"28.6","Cell RNA - U-2 OS [nTPM]":"20.8","Cell RNA - U-2197 [nTPM]":"75.2","Cell RNA - U-251 MG [nTPM]":"54.4","Cell RNA - U-266\/70 [nTPM]":"79.3","Cell RNA - U-266\/84 [nTPM]":"28.7","Cell RNA - U-698 [nTPM]":"37.6","Cell RNA - U-87 MG [nTPM]":"82.3","Cell RNA - U-937 [nTPM]":"41.0","Cell RNA - WM-115 [nTPM]":"56.0","Blood RNA - basophil [nTPM]":"32.0","Blood RNA - classical monocyte [nTPM]":"29.3","Blood RNA - eosinophil [nTPM]":"27.4","Blood RNA - gdT-cell [nTPM]":"21.6","Blood RNA - intermediate monocyte [nTPM]":"31.8","Blood RNA - MAIT T-cell [nTPM]":"14.0","Blood RNA - memory B-cell [nTPM]":"18.5","Blood RNA - memory CD4 T-cell [nTPM]":"14.9","Blood RNA - memory CD8 T-cell [nTPM]":"17.7","Blood RNA - myeloid DC [nTPM]":"25.8","Blood RNA - naive B-cell [nTPM]":"15.3","Blood RNA - naive CD4 T-cell [nTPM]":"14.8","Blood RNA - naive CD8 T-cell [nTPM]":"17.2","Blood RNA - neutrophil [nTPM]":"8.6","Blood RNA - NK-cell [nTPM]":"41.0","Blood RNA - non-classical monocyte [nTPM]":"33.8","Blood RNA - plasmacytoid DC [nTPM]":"15.5","Blood RNA - T-reg [nTPM]":"19.9","Blood RNA - total PBMC [nTPM]":"16.4","Brain RNA - amygdala [nTPM]":"63.4","Brain RNA - basal ganglia [nTPM]":"63.8","Brain RNA - cerebellum [nTPM]":"67.0","Brain RNA - cerebral cortex [nTPM]":"81.8","Brain RNA - hippocampal formation [nTPM]":"64.0","Brain RNA - hypothalamus [nTPM]":"66.7","Brain RNA - medulla oblongata [nTPM]":"72.3","Brain RNA - midbrain [nTPM]":"64.3","Brain RNA - pons [nTPM]":"76.5","Brain RNA - spinal cord [nTPM]":"63.3","Brain RNA - thalamus [nTPM]":"67.1","Brain RNA - white matter [nTPM]":"69.7","Single Cell Type RNA - Adipocytes [nTPM]":"33.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.2","Single Cell Type RNA - Astrocytes [nTPM]":"22.2","Single Cell Type RNA - B-cells [nTPM]":"36.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"19.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"39.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"53.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"51.2","Single Cell Type RNA - Bipolar cells [nTPM]":"52.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"33.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"44.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"31.5","Single Cell Type RNA - Club cells [nTPM]":"26.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"77.0","Single Cell Type RNA - dendritic cells [nTPM]":"45.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"26.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"33.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"36.3","Single Cell Type RNA - Endothelial cells [nTPM]":"22.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"25.2","Single Cell Type RNA - Erythroid cells [nTPM]":"24.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"46.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"61.3","Single Cell Type RNA - Fibroblasts [nTPM]":"34.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"25.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"45.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.2","Single Cell Type RNA - Hepatocytes [nTPM]":"28.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"67.8","Single Cell Type RNA - Horizontal cells [nTPM]":"48.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.9","Single Cell Type RNA - Ionocytes [nTPM]":"57.0","Single Cell Type RNA - Kupffer cells [nTPM]":"35.2","Single Cell Type RNA - Langerhans cells [nTPM]":"17.5","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"36.1","Single Cell Type RNA - Macrophages [nTPM]":"34.4","Single Cell Type RNA - Melanocytes [nTPM]":"44.4","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"45.3","Single Cell Type RNA - Muller glia cells [nTPM]":"52.5","Single Cell Type RNA - NK-cells [nTPM]":"49.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"36.4","Single Cell Type RNA - Paneth cells [nTPM]":"31.2","Single Cell Type RNA - Peritubular cells [nTPM]":"22.6","Single Cell Type RNA - Plasma cells [nTPM]":"51.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"27.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"49.6","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"33.7","Single Cell Type RNA - Spermatocytes [nTPM]":"6.8","Single Cell Type RNA - Spermatogonia [nTPM]":"25.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"19.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"43.5","Single Cell Type RNA - T-cells [nTPM]":"41.7","Single Cell Type RNA - Theca cells [nTPM]":"31.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"28.3","Single Cell Type RNA - Urothelial cells [nTPM]":"21.0"},{"Gene":"B4GALNT1","Gene synonym":["beta1-4GalNAc-T","GALGT","SPG26"],"Ensembl":"ENSG00000135454","Gene description":"Beta-1,4-N-acetyl-galactosaminyltransferase 1","Uniprot":["Q00973"],"Chromosome":"12","Position":"57623409-57633239","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"61.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"10.0","Excitatory neurons":"22.0","Horizontal cells":"21.9","Inhibitory neurons":"13.4","Smooth muscle cells":"7.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"10.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"67.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008968"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"35000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 9: U-2 OS - Unknown function","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA008968":"AB_1078253"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.18e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-4"},"Tissue RNA - adipose tissue [nTPM]":"1.9","Tissue RNA - adrenal gland [nTPM]":"1.1","Tissue RNA - amygdala [nTPM]":"26.9","Tissue RNA - appendix [nTPM]":"1.9","Tissue RNA - basal ganglia [nTPM]":"29.7","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.7","Tissue RNA - cerebellum [nTPM]":"29.3","Tissue RNA - cerebral cortex [nTPM]":"61.1","Tissue RNA - cervix [nTPM]":"1.3","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"2.7","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"2.1","Tissue RNA - epididymis [nTPM]":"2.7","Tissue RNA - esophagus [nTPM]":"0.7","Tissue RNA - fallopian tube [nTPM]":"0.7","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"3.3","Tissue RNA - hippocampal formation [nTPM]":"34.9","Tissue RNA - hypothalamus [nTPM]":"21.9","Tissue RNA - kidney [nTPM]":"0.8","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"0.6","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"16.7","Tissue RNA - midbrain [nTPM]":"11.8","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"1.7","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"20.5","Tissue RNA - prostate [nTPM]":"2.6","Tissue RNA - rectum [nTPM]":"1.2","Tissue RNA - retina [nTPM]":"4.2","Tissue RNA - salivary gland [nTPM]":"1.8","Tissue RNA - seminal vesicle [nTPM]":"5.0","Tissue RNA - skeletal muscle [nTPM]":"9.5","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"1.2","Tissue RNA - smooth muscle [nTPM]":"2.5","Tissue RNA - spinal cord [nTPM]":"8.1","Tissue RNA - spleen [nTPM]":"0.6","Tissue RNA - stomach 1 [nTPM]":"0.9","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"19.1","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"1.2","Tissue RNA - tongue [nTPM]":"7.2","Tissue RNA - tonsil [nTPM]":"1.0","Tissue RNA - urinary bladder [nTPM]":"1.2","Tissue RNA - vagina [nTPM]":"1.6","Tissue RNA - white matter [nTPM]":"29.9","Cell RNA - A-431 [nTPM]":"7.5","Cell RNA - A549 [nTPM]":"38.2","Cell RNA - AF22 [nTPM]":"18.2","Cell RNA - AN3-CA [nTPM]":"38.7","Cell RNA - ASC diff [nTPM]":"0.3","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"3.0","Cell RNA - BJ hTERT+ [nTPM]":"11.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.5","Cell RNA - CACO-2 [nTPM]":"2.8","Cell RNA - CAPAN-2 [nTPM]":"21.9","Cell RNA - Daudi [nTPM]":"3.0","Cell RNA - EFO-21 [nTPM]":"47.9","Cell RNA - fHDF\/TERT166 [nTPM]":"13.2","Cell RNA - GAMG [nTPM]":"35.9","Cell RNA - HaCaT [nTPM]":"3.3","Cell RNA - HAP1 [nTPM]":"15.3","Cell RNA - HBEC3-KT [nTPM]":"2.1","Cell RNA - HBF TERT88 [nTPM]":"5.2","Cell RNA - HDLM-2 [nTPM]":"67.4","Cell RNA - HEK 293 [nTPM]":"2.6","Cell RNA - HEL [nTPM]":"1.8","Cell RNA - HeLa [nTPM]":"10.1","Cell RNA - Hep G2 [nTPM]":"9.9","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"3.1","Cell RNA - HMC-1 [nTPM]":"4.1","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.0","Cell RNA - hTERT-HME1 [nTPM]":"0.5","Cell RNA - hTERT-RPE1 [nTPM]":"6.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"11.4","Cell RNA - K-562 [nTPM]":"8.7","Cell RNA - Karpas-707 [nTPM]":"34.8","Cell RNA - LHCN-M2 [nTPM]":"2.4","Cell RNA - MCF7 [nTPM]":"13.5","Cell RNA - MOLT-4 [nTPM]":"2.5","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"13.0","Cell RNA - OE19 [nTPM]":"0.9","Cell RNA - PC-3 [nTPM]":"7.7","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"27.1","Cell RNA - RPMI-8226 [nTPM]":"8.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"34.9","Cell RNA - SH-SY5Y [nTPM]":"12.3","Cell RNA - SiHa [nTPM]":"3.1","Cell RNA - SK-BR-3 [nTPM]":"1.1","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"0.9","Cell RNA - T-47d [nTPM]":"7.0","Cell RNA - THP-1 [nTPM]":"3.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"22.8","Cell RNA - U-2 OS [nTPM]":"28.1","Cell RNA - U-2197 [nTPM]":"24.0","Cell RNA - U-251 MG [nTPM]":"26.1","Cell RNA - U-266\/70 [nTPM]":"37.0","Cell RNA - U-266\/84 [nTPM]":"34.0","Cell RNA - U-698 [nTPM]":"2.6","Cell RNA - U-87 MG [nTPM]":"28.9","Cell RNA - U-937 [nTPM]":"2.3","Cell RNA - WM-115 [nTPM]":"45.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"26.9","Brain RNA - basal ganglia [nTPM]":"29.7","Brain RNA - cerebellum [nTPM]":"29.3","Brain RNA - cerebral cortex [nTPM]":"61.1","Brain RNA - hippocampal formation [nTPM]":"34.9","Brain RNA - hypothalamus [nTPM]":"21.9","Brain RNA - medulla oblongata [nTPM]":"16.7","Brain RNA - midbrain [nTPM]":"11.8","Brain RNA - pons [nTPM]":"20.5","Brain RNA - spinal cord [nTPM]":"8.1","Brain RNA - thalamus [nTPM]":"19.1","Brain RNA - white matter [nTPM]":"29.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"10.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"1.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"2.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.5","Single Cell Type RNA - Spermatocytes [nTPM]":"1.6","Single Cell Type RNA - Spermatogonia [nTPM]":"4.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"B4GALT1","Gene synonym":["beta4Gal-T1","GGTB2"],"Ensembl":"ENSG00000086062","Gene description":"Beta-1,4-galactosyltransferase 1","Uniprot":["P15291"],"Chromosome":"9","Position":"33104082-33167356","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"333.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"215.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"346.6","SiHa":"635.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010806","HPA010807"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"97000000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 30: Mammary glandular cells - Lactation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA010806":"AB_1078255","HPA010807":"AB_1078254"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.85e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.25e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.93e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Tissue RNA - adipose tissue [nTPM]":"52.4","Tissue RNA - adrenal gland [nTPM]":"39.2","Tissue RNA - amygdala [nTPM]":"5.6","Tissue RNA - appendix [nTPM]":"43.9","Tissue RNA - basal ganglia [nTPM]":"5.1","Tissue RNA - bone marrow [nTPM]":"80.2","Tissue RNA - breast [nTPM]":"91.1","Tissue RNA - cerebellum [nTPM]":"7.3","Tissue RNA - cerebral cortex [nTPM]":"6.4","Tissue RNA - cervix [nTPM]":"64.9","Tissue RNA - choroid plexus [nTPM]":"17.9","Tissue RNA - colon [nTPM]":"38.0","Tissue RNA - duodenum [nTPM]":"21.9","Tissue RNA - endometrium 1 [nTPM]":"35.7","Tissue RNA - epididymis [nTPM]":"35.7","Tissue RNA - esophagus [nTPM]":"49.7","Tissue RNA - fallopian tube [nTPM]":"49.3","Tissue RNA - gallbladder [nTPM]":"47.8","Tissue RNA - heart muscle [nTPM]":"55.4","Tissue RNA - hippocampal formation [nTPM]":"5.4","Tissue RNA - hypothalamus [nTPM]":"6.8","Tissue RNA - kidney [nTPM]":"42.1","Tissue RNA - liver [nTPM]":"89.4","Tissue RNA - lung [nTPM]":"50.1","Tissue RNA - lymph node [nTPM]":"33.3","Tissue RNA - medulla oblongata [nTPM]":"8.6","Tissue RNA - midbrain [nTPM]":"6.4","Tissue RNA - ovary [nTPM]":"77.4","Tissue RNA - pancreas [nTPM]":"43.9","Tissue RNA - parathyroid gland [nTPM]":"77.1","Tissue RNA - pituitary gland [nTPM]":"21.2","Tissue RNA - placenta [nTPM]":"52.9","Tissue RNA - pons [nTPM]":"7.7","Tissue RNA - prostate [nTPM]":"38.8","Tissue RNA - rectum [nTPM]":"34.3","Tissue RNA - retina [nTPM]":"26.2","Tissue RNA - salivary gland [nTPM]":"70.3","Tissue RNA - seminal vesicle [nTPM]":"34.0","Tissue RNA - skeletal muscle [nTPM]":"30.9","Tissue RNA - skin 1 [nTPM]":"35.8","Tissue RNA - small intestine [nTPM]":"28.1","Tissue RNA - smooth muscle [nTPM]":"55.2","Tissue RNA - spinal cord [nTPM]":"8.1","Tissue RNA - spleen [nTPM]":"39.7","Tissue RNA - stomach 1 [nTPM]":"52.1","Tissue RNA - testis [nTPM]":"38.3","Tissue RNA - thalamus [nTPM]":"8.3","Tissue RNA - thymus [nTPM]":"26.8","Tissue RNA - thyroid gland [nTPM]":"60.8","Tissue RNA - tongue [nTPM]":"16.7","Tissue RNA - tonsil [nTPM]":"41.2","Tissue RNA - urinary bladder [nTPM]":"79.4","Tissue RNA - vagina [nTPM]":"44.9","Tissue RNA - white matter [nTPM]":"9.4","Cell RNA - A-431 [nTPM]":"99.1","Cell RNA - A549 [nTPM]":"71.8","Cell RNA - AF22 [nTPM]":"13.1","Cell RNA - AN3-CA [nTPM]":"18.1","Cell RNA - ASC diff [nTPM]":"64.9","Cell RNA - ASC TERT1 [nTPM]":"113.7","Cell RNA - BEWO [nTPM]":"235.9","Cell RNA - BJ [nTPM]":"100.6","Cell RNA - BJ hTERT+ [nTPM]":"125.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"59.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"58.8","Cell RNA - CACO-2 [nTPM]":"44.0","Cell RNA - CAPAN-2 [nTPM]":"112.1","Cell RNA - Daudi [nTPM]":"37.8","Cell RNA - EFO-21 [nTPM]":"62.4","Cell RNA - fHDF\/TERT166 [nTPM]":"147.3","Cell RNA - GAMG [nTPM]":"77.2","Cell RNA - HaCaT [nTPM]":"51.9","Cell RNA - HAP1 [nTPM]":"13.7","Cell RNA - HBEC3-KT [nTPM]":"124.5","Cell RNA - HBF TERT88 [nTPM]":"59.4","Cell RNA - HDLM-2 [nTPM]":"346.6","Cell RNA - HEK 293 [nTPM]":"13.6","Cell RNA - HEL [nTPM]":"21.6","Cell RNA - HeLa [nTPM]":"277.6","Cell RNA - Hep G2 [nTPM]":"34.1","Cell RNA - HHSteC [nTPM]":"127.4","Cell RNA - HL-60 [nTPM]":"17.9","Cell RNA - HMC-1 [nTPM]":"35.0","Cell RNA - HSkMC [nTPM]":"128.0","Cell RNA - hTCEpi [nTPM]":"218.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"68.0","Cell RNA - hTERT-HME1 [nTPM]":"82.2","Cell RNA - hTERT-RPE1 [nTPM]":"127.6","Cell RNA - HUVEC TERT2 [nTPM]":"64.0","Cell RNA - JURKAT [nTPM]":"11.5","Cell RNA - K-562 [nTPM]":"24.9","Cell RNA - Karpas-707 [nTPM]":"45.5","Cell RNA - LHCN-M2 [nTPM]":"57.0","Cell RNA - MCF7 [nTPM]":"86.1","Cell RNA - MOLT-4 [nTPM]":"16.3","Cell RNA - NB-4 [nTPM]":"35.4","Cell RNA - NTERA-2 [nTPM]":"8.1","Cell RNA - OE19 [nTPM]":"54.1","Cell RNA - PC-3 [nTPM]":"21.8","Cell RNA - REH [nTPM]":"21.0","Cell RNA - RH-30 [nTPM]":"12.2","Cell RNA - RPMI-8226 [nTPM]":"25.1","Cell RNA - RPTEC TERT1 [nTPM]":"177.0","Cell RNA - RT4 [nTPM]":"84.6","Cell RNA - SCLC-21H [nTPM]":"9.8","Cell RNA - SH-SY5Y [nTPM]":"12.7","Cell RNA - SiHa [nTPM]":"635.5","Cell RNA - SK-BR-3 [nTPM]":"122.2","Cell RNA - SK-MEL-30 [nTPM]":"25.8","Cell RNA - SuSa [nTPM]":"40.4","Cell RNA - T-47d [nTPM]":"154.8","Cell RNA - THP-1 [nTPM]":"32.3","Cell RNA - TIME [nTPM]":"59.9","Cell RNA - U-138 MG [nTPM]":"42.2","Cell RNA - U-2 OS [nTPM]":"49.4","Cell RNA - U-2197 [nTPM]":"137.2","Cell RNA - U-251 MG [nTPM]":"39.8","Cell RNA - U-266\/70 [nTPM]":"7.6","Cell RNA - U-266\/84 [nTPM]":"17.9","Cell RNA - U-698 [nTPM]":"23.3","Cell RNA - U-87 MG [nTPM]":"131.0","Cell RNA - U-937 [nTPM]":"24.2","Cell RNA - WM-115 [nTPM]":"15.8","Blood RNA - basophil [nTPM]":"30.6","Blood RNA - classical monocyte [nTPM]":"33.2","Blood RNA - eosinophil [nTPM]":"20.3","Blood RNA - gdT-cell [nTPM]":"45.2","Blood RNA - intermediate monocyte [nTPM]":"30.5","Blood RNA - MAIT T-cell [nTPM]":"59.2","Blood RNA - memory B-cell [nTPM]":"87.1","Blood RNA - memory CD4 T-cell [nTPM]":"30.4","Blood RNA - memory CD8 T-cell [nTPM]":"40.7","Blood RNA - myeloid DC [nTPM]":"23.3","Blood RNA - naive B-cell [nTPM]":"69.9","Blood RNA - naive CD4 T-cell [nTPM]":"17.9","Blood RNA - naive CD8 T-cell [nTPM]":"23.3","Blood RNA - neutrophil [nTPM]":"96.5","Blood RNA - NK-cell [nTPM]":"72.4","Blood RNA - non-classical monocyte [nTPM]":"24.8","Blood RNA - plasmacytoid DC [nTPM]":"215.3","Blood RNA - T-reg [nTPM]":"22.0","Blood RNA - total PBMC [nTPM]":"24.0","Brain RNA - amygdala [nTPM]":"5.6","Brain RNA - basal ganglia [nTPM]":"5.1","Brain RNA - cerebellum [nTPM]":"7.3","Brain RNA - cerebral cortex [nTPM]":"6.4","Brain RNA - hippocampal formation [nTPM]":"5.4","Brain RNA - hypothalamus [nTPM]":"6.8","Brain RNA - medulla oblongata [nTPM]":"8.6","Brain RNA - midbrain [nTPM]":"6.4","Brain RNA - pons [nTPM]":"7.7","Brain RNA - spinal cord [nTPM]":"8.1","Brain RNA - thalamus [nTPM]":"8.3","Brain RNA - white matter [nTPM]":"9.4","Single Cell Type RNA - Adipocytes [nTPM]":"104.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"86.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"71.9","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"112.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"141.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"53.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"59.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"75.7","Single Cell Type RNA - Bipolar cells [nTPM]":"3.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"215.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"66.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"37.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"88.6","Single Cell Type RNA - Club cells [nTPM]":"59.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"167.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"94.9","Single Cell Type RNA - dendritic cells [nTPM]":"206.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"146.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"78.2","Single Cell Type RNA - Early spermatids [nTPM]":"21.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"108.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"39.7","Single Cell Type RNA - Endothelial cells [nTPM]":"60.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"12.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"125.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"155.8","Single Cell Type RNA - Fibroblasts [nTPM]":"99.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"80.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"163.7","Single Cell Type RNA - granulocytes [nTPM]":"36.8","Single Cell Type RNA - Granulosa cells [nTPM]":"19.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"91.1","Single Cell Type RNA - Hepatocytes [nTPM]":"195.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"53.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"64.0","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"82.3","Single Cell Type RNA - Langerhans cells [nTPM]":"333.3","Single Cell Type RNA - Late spermatids [nTPM]":"11.1","Single Cell Type RNA - Leydig cells [nTPM]":"50.7","Single Cell Type RNA - Macrophages [nTPM]":"129.0","Single Cell Type RNA - Melanocytes [nTPM]":"96.0","Single Cell Type RNA - Microglial cells [nTPM]":"33.7","Single Cell Type RNA - monocytes [nTPM]":"31.3","Single Cell Type RNA - Muller glia cells [nTPM]":"7.7","Single Cell Type RNA - NK-cells [nTPM]":"39.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"157.8","Single Cell Type RNA - Paneth cells [nTPM]":"57.4","Single Cell Type RNA - Peritubular cells [nTPM]":"44.4","Single Cell Type RNA - Plasma cells [nTPM]":"116.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"89.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"57.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"40.1","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"80.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"50.8","Single Cell Type RNA - Spermatocytes [nTPM]":"6.4","Single Cell Type RNA - Spermatogonia [nTPM]":"13.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"86.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"108.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"173.9","Single Cell Type RNA - T-cells [nTPM]":"92.7","Single Cell Type RNA - Theca cells [nTPM]":"33.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"41.6","Single Cell Type RNA - Urothelial cells [nTPM]":"93.2"},{"Gene":"B4GALT7","Gene synonym":["beta4Gal-T7","XGALT-1"],"Ensembl":"ENSG00000027847","Gene description":"Beta-1,4-galactosyltransferase 7","Uniprot":["Q9UBV7"],"Chromosome":"5","Position":"177600132-177610330","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant","Dwarfism","Ehlers-Danlos syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"132.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042330"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042330":"AB_10796576"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.29e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Tissue RNA - adipose tissue [nTPM]":"19.0","Tissue RNA - adrenal gland [nTPM]":"43.7","Tissue RNA - amygdala [nTPM]":"21.1","Tissue RNA - appendix [nTPM]":"15.3","Tissue RNA - basal ganglia [nTPM]":"20.1","Tissue RNA - bone marrow [nTPM]":"24.8","Tissue RNA - breast [nTPM]":"17.0","Tissue RNA - cerebellum [nTPM]":"20.6","Tissue RNA - cerebral cortex [nTPM]":"25.5","Tissue RNA - cervix [nTPM]":"18.4","Tissue RNA - choroid plexus [nTPM]":"21.8","Tissue RNA - colon [nTPM]":"15.1","Tissue RNA - duodenum [nTPM]":"16.9","Tissue RNA - endometrium 1 [nTPM]":"20.1","Tissue RNA - epididymis [nTPM]":"12.5","Tissue RNA - esophagus [nTPM]":"16.6","Tissue RNA - fallopian tube [nTPM]":"16.0","Tissue RNA - gallbladder [nTPM]":"12.5","Tissue RNA - heart muscle [nTPM]":"23.4","Tissue RNA - hippocampal formation [nTPM]":"20.1","Tissue RNA - hypothalamus [nTPM]":"21.8","Tissue RNA - kidney [nTPM]":"20.2","Tissue RNA - liver [nTPM]":"30.5","Tissue RNA - lung [nTPM]":"13.4","Tissue RNA - lymph node [nTPM]":"20.1","Tissue RNA - medulla oblongata [nTPM]":"24.8","Tissue RNA - midbrain [nTPM]":"25.1","Tissue RNA - ovary [nTPM]":"19.8","Tissue RNA - pancreas [nTPM]":"37.6","Tissue RNA - parathyroid gland [nTPM]":"24.3","Tissue RNA - pituitary gland [nTPM]":"31.5","Tissue RNA - placenta [nTPM]":"14.1","Tissue RNA - pons [nTPM]":"24.8","Tissue RNA - prostate [nTPM]":"22.5","Tissue RNA - rectum [nTPM]":"11.9","Tissue RNA - retina [nTPM]":"5.9","Tissue RNA - salivary gland [nTPM]":"24.2","Tissue RNA - seminal vesicle [nTPM]":"18.8","Tissue RNA - skeletal muscle [nTPM]":"20.2","Tissue RNA - skin 1 [nTPM]":"13.6","Tissue RNA - small intestine [nTPM]":"14.7","Tissue RNA - smooth muscle [nTPM]":"11.8","Tissue RNA - spinal cord [nTPM]":"18.5","Tissue RNA - spleen [nTPM]":"21.3","Tissue RNA - stomach 1 [nTPM]":"21.8","Tissue RNA - testis [nTPM]":"23.9","Tissue RNA - thalamus [nTPM]":"22.1","Tissue RNA - thymus [nTPM]":"10.6","Tissue RNA - thyroid gland [nTPM]":"18.5","Tissue RNA - tongue [nTPM]":"10.1","Tissue RNA - tonsil [nTPM]":"11.8","Tissue RNA - urinary bladder [nTPM]":"17.9","Tissue RNA - vagina [nTPM]":"13.9","Tissue RNA - white matter [nTPM]":"18.7","Cell RNA - A-431 [nTPM]":"20.2","Cell RNA - A549 [nTPM]":"34.5","Cell RNA - AF22 [nTPM]":"14.2","Cell RNA - AN3-CA [nTPM]":"35.6","Cell RNA - ASC diff [nTPM]":"28.0","Cell RNA - ASC TERT1 [nTPM]":"20.7","Cell RNA - BEWO [nTPM]":"63.7","Cell RNA - BJ [nTPM]":"30.1","Cell RNA - BJ hTERT+ [nTPM]":"31.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"26.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"30.7","Cell RNA - CACO-2 [nTPM]":"32.6","Cell RNA - CAPAN-2 [nTPM]":"30.8","Cell RNA - Daudi [nTPM]":"25.2","Cell RNA - EFO-21 [nTPM]":"54.7","Cell RNA - fHDF\/TERT166 [nTPM]":"30.9","Cell RNA - GAMG [nTPM]":"47.3","Cell RNA - HaCaT [nTPM]":"22.9","Cell RNA - HAP1 [nTPM]":"9.8","Cell RNA - HBEC3-KT [nTPM]":"64.9","Cell RNA - HBF TERT88 [nTPM]":"11.7","Cell RNA - HDLM-2 [nTPM]":"85.4","Cell RNA - HEK 293 [nTPM]":"25.8","Cell RNA - HEL [nTPM]":"13.3","Cell RNA - HeLa [nTPM]":"27.5","Cell RNA - Hep G2 [nTPM]":"23.4","Cell RNA - HHSteC [nTPM]":"40.0","Cell RNA - HL-60 [nTPM]":"13.8","Cell RNA - HMC-1 [nTPM]":"22.4","Cell RNA - HSkMC [nTPM]":"31.8","Cell RNA - hTCEpi [nTPM]":"22.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"29.0","Cell RNA - hTERT-HME1 [nTPM]":"23.5","Cell RNA - hTERT-RPE1 [nTPM]":"24.7","Cell RNA - HUVEC TERT2 [nTPM]":"30.3","Cell RNA - JURKAT [nTPM]":"16.9","Cell RNA - K-562 [nTPM]":"11.8","Cell RNA - Karpas-707 [nTPM]":"23.7","Cell RNA - LHCN-M2 [nTPM]":"27.4","Cell RNA - MCF7 [nTPM]":"46.0","Cell RNA - MOLT-4 [nTPM]":"11.9","Cell RNA - NB-4 [nTPM]":"17.1","Cell RNA - NTERA-2 [nTPM]":"13.9","Cell RNA - OE19 [nTPM]":"17.7","Cell RNA - PC-3 [nTPM]":"50.0","Cell RNA - REH [nTPM]":"24.1","Cell RNA - RH-30 [nTPM]":"10.3","Cell RNA - RPMI-8226 [nTPM]":"27.8","Cell RNA - RPTEC TERT1 [nTPM]":"20.6","Cell RNA - RT4 [nTPM]":"29.6","Cell RNA - SCLC-21H [nTPM]":"12.5","Cell RNA - SH-SY5Y [nTPM]":"14.4","Cell RNA - SiHa [nTPM]":"15.0","Cell RNA - SK-BR-3 [nTPM]":"29.8","Cell RNA - SK-MEL-30 [nTPM]":"27.6","Cell RNA - SuSa [nTPM]":"11.3","Cell RNA - T-47d [nTPM]":"19.4","Cell RNA - THP-1 [nTPM]":"16.3","Cell RNA - TIME [nTPM]":"23.5","Cell RNA - U-138 MG [nTPM]":"34.0","Cell RNA - U-2 OS [nTPM]":"19.5","Cell RNA - U-2197 [nTPM]":"22.6","Cell RNA - U-251 MG [nTPM]":"30.6","Cell RNA - U-266\/70 [nTPM]":"29.5","Cell RNA - U-266\/84 [nTPM]":"14.9","Cell RNA - U-698 [nTPM]":"18.4","Cell RNA - U-87 MG [nTPM]":"28.8","Cell RNA - U-937 [nTPM]":"33.0","Cell RNA - WM-115 [nTPM]":"31.8","Blood RNA - basophil [nTPM]":"16.8","Blood RNA - classical monocyte [nTPM]":"16.7","Blood RNA - eosinophil [nTPM]":"9.7","Blood RNA - gdT-cell [nTPM]":"14.0","Blood RNA - intermediate monocyte [nTPM]":"19.7","Blood RNA - MAIT T-cell [nTPM]":"12.6","Blood RNA - memory B-cell [nTPM]":"14.4","Blood RNA - memory CD4 T-cell [nTPM]":"12.8","Blood RNA - memory CD8 T-cell [nTPM]":"12.2","Blood RNA - myeloid DC [nTPM]":"19.3","Blood RNA - naive B-cell [nTPM]":"18.4","Blood RNA - naive CD4 T-cell [nTPM]":"11.4","Blood RNA - naive CD8 T-cell [nTPM]":"11.3","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"11.1","Blood RNA - non-classical monocyte [nTPM]":"19.4","Blood RNA - plasmacytoid DC [nTPM]":"15.2","Blood RNA - T-reg [nTPM]":"9.2","Blood RNA - total PBMC [nTPM]":"10.9","Brain RNA - amygdala [nTPM]":"21.1","Brain RNA - basal ganglia [nTPM]":"20.1","Brain RNA - cerebellum [nTPM]":"20.6","Brain RNA - cerebral cortex [nTPM]":"25.5","Brain RNA - hippocampal formation [nTPM]":"20.1","Brain RNA - hypothalamus [nTPM]":"21.8","Brain RNA - medulla oblongata [nTPM]":"24.8","Brain RNA - midbrain [nTPM]":"25.1","Brain RNA - pons [nTPM]":"24.8","Brain RNA - spinal cord [nTPM]":"18.5","Brain RNA - thalamus [nTPM]":"22.1","Brain RNA - white matter [nTPM]":"18.7","Single Cell Type RNA - Adipocytes [nTPM]":"16.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.6","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"24.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"27.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Bipolar cells [nTPM]":"12.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"19.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"15.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"43.8","Single Cell Type RNA - dendritic cells [nTPM]":"16.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"34.1","Single Cell Type RNA - Early spermatids [nTPM]":"13.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.8","Single Cell Type RNA - Endothelial cells [nTPM]":"15.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.5","Single Cell Type RNA - Erythroid cells [nTPM]":"8.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"38.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"132.4","Single Cell Type RNA - Fibroblasts [nTPM]":"21.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.5","Single Cell Type RNA - granulocytes [nTPM]":"10.2","Single Cell Type RNA - Granulosa cells [nTPM]":"30.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.8","Single Cell Type RNA - Hepatocytes [nTPM]":"15.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"31.7","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"22.2","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"17.8","Single Cell Type RNA - Langerhans cells [nTPM]":"8.9","Single Cell Type RNA - Late spermatids [nTPM]":"9.8","Single Cell Type RNA - Leydig cells [nTPM]":"14.0","Single Cell Type RNA - Macrophages [nTPM]":"18.8","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"25.6","Single Cell Type RNA - Muller glia cells [nTPM]":"13.7","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"34.0","Single Cell Type RNA - Paneth cells [nTPM]":"12.4","Single Cell Type RNA - Peritubular cells [nTPM]":"18.4","Single Cell Type RNA - Plasma cells [nTPM]":"52.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.4","Single Cell Type RNA - Spermatocytes [nTPM]":"14.3","Single Cell Type RNA - Spermatogonia [nTPM]":"11.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"43.9","Single Cell Type RNA - T-cells [nTPM]":"12.8","Single Cell Type RNA - Theca cells [nTPM]":"33.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.3","Single Cell Type RNA - Urothelial cells [nTPM]":"16.3"},{"Gene":"BAAT","Gene synonym":["BAT"],"Ensembl":"ENSG00000136881","Gene description":"Bile acid-CoA:amino acid N-acyltransferase","Uniprot":["Q14032"],"Chromosome":"9","Position":"101354182-101385400","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Acyltransferase","Hydrolase","Serine esterase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"41","RNA tissue specific nTPM":{"liver":"721.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Hepatocytes":"996.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"42","RNA cancer specific FPKM":{"liver cancer":"181.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"3.4","CACO-2":"1.6"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021251","HPA021330"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"520000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA021251":"AB_1845247","HPA021330":"AB_2670674"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.97e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.97e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.24e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"1.2","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"1.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"17.4","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.4","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"721.0","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.9","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.5","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"1.1","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.7","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"3.4","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"1.6","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.8","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.8","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"1.0","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.4","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.5","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"2.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"91.5","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"8.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"16.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.1","Single Cell Type RNA - Hepatocytes [nTPM]":"996.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"18.2","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"BAP1","Gene synonym":["hucep-6","KIAA0272","UCHL2"],"Ensembl":"ENSG00000163930","Gene description":"BRCA1 associated protein 1","Uniprot":["Q92560"],"Chromosome":"3","Position":"52401008-52410008","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Chromatin regulator","Hydrolase","Protease","Thiol protease"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"103.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004322","HPA028814","HPA028815","HPA055560"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB004322":"AB_626723","HPA028814":"AB_10602393","HPA028815":"AB_2672785","HPA055560":"AB_2682850"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.53e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.29e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Tissue RNA - adipose tissue [nTPM]":"45.2","Tissue RNA - adrenal gland [nTPM]":"63.5","Tissue RNA - amygdala [nTPM]":"97.6","Tissue RNA - appendix [nTPM]":"25.0","Tissue RNA - basal ganglia [nTPM]":"99.2","Tissue RNA - bone marrow [nTPM]":"73.9","Tissue RNA - breast [nTPM]":"42.9","Tissue RNA - cerebellum [nTPM]":"78.9","Tissue RNA - cerebral cortex [nTPM]":"135.5","Tissue RNA - cervix [nTPM]":"39.1","Tissue RNA - choroid plexus [nTPM]":"71.4","Tissue RNA - colon [nTPM]":"47.7","Tissue RNA - duodenum [nTPM]":"21.6","Tissue RNA - endometrium 1 [nTPM]":"40.5","Tissue RNA - epididymis [nTPM]":"23.1","Tissue RNA - esophagus [nTPM]":"59.3","Tissue RNA - fallopian tube [nTPM]":"36.0","Tissue RNA - gallbladder [nTPM]":"25.7","Tissue RNA - heart muscle [nTPM]":"57.0","Tissue RNA - hippocampal formation [nTPM]":"114.1","Tissue RNA - hypothalamus [nTPM]":"83.3","Tissue RNA - kidney [nTPM]":"57.3","Tissue RNA - liver [nTPM]":"65.2","Tissue RNA - lung [nTPM]":"46.0","Tissue RNA - lymph node [nTPM]":"29.4","Tissue RNA - medulla oblongata [nTPM]":"81.2","Tissue RNA - midbrain [nTPM]":"85.7","Tissue RNA - ovary [nTPM]":"43.9","Tissue RNA - pancreas [nTPM]":"52.7","Tissue RNA - parathyroid gland [nTPM]":"40.2","Tissue RNA - pituitary gland [nTPM]":"36.9","Tissue RNA - placenta [nTPM]":"24.6","Tissue RNA - pons [nTPM]":"81.7","Tissue RNA - prostate [nTPM]":"50.0","Tissue RNA - rectum [nTPM]":"24.1","Tissue RNA - retina [nTPM]":"20.1","Tissue RNA - salivary gland [nTPM]":"43.0","Tissue RNA - seminal vesicle [nTPM]":"22.5","Tissue RNA - skeletal muscle [nTPM]":"74.7","Tissue RNA - skin 1 [nTPM]":"73.4","Tissue RNA - small intestine [nTPM]":"43.4","Tissue RNA - smooth muscle [nTPM]":"23.8","Tissue RNA - spinal cord [nTPM]":"79.9","Tissue RNA - spleen [nTPM]":"54.2","Tissue RNA - stomach 1 [nTPM]":"48.1","Tissue RNA - testis [nTPM]":"140.0","Tissue RNA - thalamus [nTPM]":"89.2","Tissue RNA - thymus [nTPM]":"33.1","Tissue RNA - thyroid gland [nTPM]":"49.1","Tissue RNA - tongue [nTPM]":"43.5","Tissue RNA - tonsil [nTPM]":"27.9","Tissue RNA - urinary bladder [nTPM]":"44.6","Tissue RNA - vagina [nTPM]":"41.7","Tissue RNA - white matter [nTPM]":"90.5","Cell RNA - A-431 [nTPM]":"39.1","Cell RNA - A549 [nTPM]":"43.1","Cell RNA - AF22 [nTPM]":"52.2","Cell RNA - AN3-CA [nTPM]":"44.8","Cell RNA - ASC diff [nTPM]":"50.1","Cell RNA - ASC TERT1 [nTPM]":"31.4","Cell RNA - BEWO [nTPM]":"59.3","Cell RNA - BJ [nTPM]":"37.8","Cell RNA - BJ hTERT+ [nTPM]":"50.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"62.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"48.0","Cell RNA - CACO-2 [nTPM]":"52.5","Cell RNA - CAPAN-2 [nTPM]":"35.8","Cell RNA - Daudi [nTPM]":"55.7","Cell RNA - EFO-21 [nTPM]":"18.3","Cell RNA - fHDF\/TERT166 [nTPM]":"54.7","Cell RNA - GAMG [nTPM]":"69.3","Cell RNA - HaCaT [nTPM]":"31.4","Cell RNA - HAP1 [nTPM]":"55.7","Cell RNA - HBEC3-KT [nTPM]":"63.0","Cell RNA - HBF TERT88 [nTPM]":"37.9","Cell RNA - HDLM-2 [nTPM]":"55.1","Cell RNA - HEK 293 [nTPM]":"51.4","Cell RNA - HEL [nTPM]":"68.6","Cell RNA - HeLa [nTPM]":"94.4","Cell RNA - Hep G2 [nTPM]":"53.2","Cell RNA - HHSteC [nTPM]":"45.7","Cell RNA - HL-60 [nTPM]":"65.6","Cell RNA - HMC-1 [nTPM]":"58.5","Cell RNA - HSkMC [nTPM]":"48.0","Cell RNA - hTCEpi [nTPM]":"80.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"68.5","Cell RNA - hTERT-HME1 [nTPM]":"36.1","Cell RNA - hTERT-RPE1 [nTPM]":"33.3","Cell RNA - HUVEC TERT2 [nTPM]":"50.3","Cell RNA - JURKAT [nTPM]":"107.7","Cell RNA - K-562 [nTPM]":"59.9","Cell RNA - Karpas-707 [nTPM]":"48.3","Cell RNA - LHCN-M2 [nTPM]":"44.5","Cell RNA - MCF7 [nTPM]":"33.7","Cell RNA - MOLT-4 [nTPM]":"79.1","Cell RNA - NB-4 [nTPM]":"89.5","Cell RNA - NTERA-2 [nTPM]":"58.0","Cell RNA - OE19 [nTPM]":"31.0","Cell RNA - PC-3 [nTPM]":"52.8","Cell RNA - REH [nTPM]":"33.7","Cell RNA - RH-30 [nTPM]":"41.7","Cell RNA - RPMI-8226 [nTPM]":"55.8","Cell RNA - RPTEC TERT1 [nTPM]":"37.4","Cell RNA - RT4 [nTPM]":"61.2","Cell RNA - SCLC-21H [nTPM]":"19.8","Cell RNA - SH-SY5Y [nTPM]":"63.6","Cell RNA - SiHa [nTPM]":"46.1","Cell RNA - SK-BR-3 [nTPM]":"13.7","Cell RNA - SK-MEL-30 [nTPM]":"56.9","Cell RNA - SuSa [nTPM]":"29.2","Cell RNA - T-47d [nTPM]":"37.7","Cell RNA - THP-1 [nTPM]":"90.6","Cell RNA - TIME [nTPM]":"52.5","Cell RNA - U-138 MG [nTPM]":"54.1","Cell RNA - U-2 OS [nTPM]":"49.3","Cell RNA - U-2197 [nTPM]":"66.0","Cell RNA - U-251 MG [nTPM]":"70.9","Cell RNA - U-266\/70 [nTPM]":"71.7","Cell RNA - U-266\/84 [nTPM]":"101.6","Cell RNA - U-698 [nTPM]":"81.2","Cell RNA - U-87 MG [nTPM]":"58.5","Cell RNA - U-937 [nTPM]":"68.2","Cell RNA - WM-115 [nTPM]":"66.1","Blood RNA - basophil [nTPM]":"2.9","Blood RNA - classical monocyte [nTPM]":"3.2","Blood RNA - eosinophil [nTPM]":"5.4","Blood RNA - gdT-cell [nTPM]":"5.4","Blood RNA - intermediate monocyte [nTPM]":"2.8","Blood RNA - MAIT T-cell [nTPM]":"2.6","Blood RNA - memory B-cell [nTPM]":"3.2","Blood RNA - memory CD4 T-cell [nTPM]":"4.3","Blood RNA - memory CD8 T-cell [nTPM]":"4.4","Blood RNA - myeloid DC [nTPM]":"2.2","Blood RNA - naive B-cell [nTPM]":"4.1","Blood RNA - naive CD4 T-cell [nTPM]":"3.1","Blood RNA - naive CD8 T-cell [nTPM]":"4.0","Blood RNA - neutrophil [nTPM]":"7.4","Blood RNA - NK-cell [nTPM]":"2.2","Blood RNA - non-classical monocyte [nTPM]":"2.2","Blood RNA - plasmacytoid DC [nTPM]":"5.6","Blood RNA - T-reg [nTPM]":"4.2","Blood RNA - total PBMC [nTPM]":"2.7","Brain RNA - amygdala [nTPM]":"97.6","Brain RNA - basal ganglia [nTPM]":"99.2","Brain RNA - cerebellum [nTPM]":"78.9","Brain RNA - cerebral cortex [nTPM]":"135.5","Brain RNA - hippocampal formation [nTPM]":"114.1","Brain RNA - hypothalamus [nTPM]":"83.3","Brain RNA - medulla oblongata [nTPM]":"81.2","Brain RNA - midbrain [nTPM]":"85.7","Brain RNA - pons [nTPM]":"81.7","Brain RNA - spinal cord [nTPM]":"79.9","Brain RNA - thalamus [nTPM]":"89.2","Brain RNA - white matter [nTPM]":"90.5","Single Cell Type RNA - Adipocytes [nTPM]":"13.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.0","Single Cell Type RNA - Astrocytes [nTPM]":"8.1","Single Cell Type RNA - B-cells [nTPM]":"12.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"31.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.3","Single Cell Type RNA - Bipolar cells [nTPM]":"16.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"23.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"10.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.0","Single Cell Type RNA - dendritic cells [nTPM]":"17.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"13.5","Single Cell Type RNA - Early spermatids [nTPM]":"103.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.4","Single Cell Type RNA - Endothelial cells [nTPM]":"14.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.8","Single Cell Type RNA - Erythroid cells [nTPM]":"8.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.8","Single Cell Type RNA - Fibroblasts [nTPM]":"13.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.6","Single Cell Type RNA - granulocytes [nTPM]":"21.0","Single Cell Type RNA - Granulosa cells [nTPM]":"18.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"29.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.6","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.6","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"17.4","Single Cell Type RNA - Langerhans cells [nTPM]":"10.7","Single Cell Type RNA - Late spermatids [nTPM]":"48.0","Single Cell Type RNA - Leydig cells [nTPM]":"10.2","Single Cell Type RNA - Macrophages [nTPM]":"12.0","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"15.2","Single Cell Type RNA - Muller glia cells [nTPM]":"16.1","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.8","Single Cell Type RNA - Paneth cells [nTPM]":"16.5","Single Cell Type RNA - Peritubular cells [nTPM]":"11.7","Single Cell Type RNA - Plasma cells [nTPM]":"16.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.3","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.2","Single Cell Type RNA - Spermatocytes [nTPM]":"37.8","Single Cell Type RNA - Spermatogonia [nTPM]":"13.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"23.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.0","Single Cell Type RNA - T-cells [nTPM]":"12.2","Single Cell Type RNA - Theca cells [nTPM]":"15.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.8","Single Cell Type RNA - Urothelial cells [nTPM]":"9.6"},{"Gene":"BAZ1B","Gene synonym":["WBSCR10","WBSCR9","WSTF"],"Ensembl":"ENSG00000009954","Gene description":"Bromodomain adjacent to zinc finger domain 1B","Uniprot":["Q9UIG0"],"Chromosome":"7","Position":"73440406-73522293","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","Transcription","Transcription regulation"],"Molecular function":["Kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Williams-Beuren syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037081","CAB037158","HPA058068"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB037081":"AB_477637","CAB037158":"AB_477636","HPA058068":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-1"},"Tissue RNA - adipose tissue [nTPM]":"22.6","Tissue RNA - adrenal gland [nTPM]":"19.4","Tissue RNA - amygdala [nTPM]":"24.1","Tissue RNA - appendix [nTPM]":"22.1","Tissue RNA - basal ganglia [nTPM]":"28.3","Tissue RNA - bone marrow [nTPM]":"24.7","Tissue RNA - breast [nTPM]":"16.7","Tissue RNA - cerebellum [nTPM]":"28.6","Tissue RNA - cerebral cortex [nTPM]":"25.2","Tissue RNA - cervix [nTPM]":"22.5","Tissue RNA - choroid plexus [nTPM]":"21.5","Tissue RNA - colon [nTPM]":"23.0","Tissue RNA - duodenum [nTPM]":"16.0","Tissue RNA - endometrium 1 [nTPM]":"24.4","Tissue RNA - epididymis [nTPM]":"17.7","Tissue RNA - esophagus [nTPM]":"18.0","Tissue RNA - fallopian tube [nTPM]":"19.3","Tissue RNA - gallbladder [nTPM]":"16.0","Tissue RNA - heart muscle [nTPM]":"19.6","Tissue RNA - hippocampal formation [nTPM]":"21.9","Tissue RNA - hypothalamus [nTPM]":"26.9","Tissue RNA - kidney [nTPM]":"16.8","Tissue RNA - liver [nTPM]":"24.1","Tissue RNA - lung [nTPM]":"20.3","Tissue RNA - lymph node [nTPM]":"27.9","Tissue RNA - medulla oblongata [nTPM]":"25.1","Tissue RNA - midbrain [nTPM]":"26.5","Tissue RNA - ovary [nTPM]":"30.8","Tissue RNA - pancreas [nTPM]":"21.0","Tissue RNA - parathyroid gland [nTPM]":"27.6","Tissue RNA - pituitary gland [nTPM]":"19.2","Tissue RNA - placenta [nTPM]":"22.7","Tissue RNA - pons [nTPM]":"24.7","Tissue RNA - prostate [nTPM]":"22.6","Tissue RNA - rectum [nTPM]":"20.5","Tissue RNA - retina [nTPM]":"28.3","Tissue RNA - salivary gland [nTPM]":"17.1","Tissue RNA - seminal vesicle [nTPM]":"25.4","Tissue RNA - skeletal muscle [nTPM]":"28.0","Tissue RNA - skin 1 [nTPM]":"14.2","Tissue RNA - small intestine [nTPM]":"18.2","Tissue RNA - smooth muscle [nTPM]":"24.7","Tissue RNA - spinal cord [nTPM]":"23.8","Tissue RNA - spleen [nTPM]":"23.4","Tissue RNA - stomach 1 [nTPM]":"18.9","Tissue RNA - testis [nTPM]":"17.3","Tissue RNA - thalamus [nTPM]":"25.5","Tissue RNA - thymus [nTPM]":"40.6","Tissue RNA - thyroid gland [nTPM]":"23.8","Tissue RNA - tongue [nTPM]":"30.7","Tissue RNA - tonsil [nTPM]":"29.6","Tissue RNA - urinary bladder [nTPM]":"21.9","Tissue RNA - vagina [nTPM]":"17.5","Tissue RNA - white matter [nTPM]":"29.1","Cell RNA - A-431 [nTPM]":"75.6","Cell RNA - A549 [nTPM]":"76.1","Cell RNA - AF22 [nTPM]":"102.5","Cell RNA - AN3-CA [nTPM]":"115.3","Cell RNA - ASC diff [nTPM]":"52.0","Cell RNA - ASC TERT1 [nTPM]":"55.1","Cell RNA - BEWO [nTPM]":"34.1","Cell RNA - BJ [nTPM]":"71.7","Cell RNA - BJ hTERT+ [nTPM]":"54.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"67.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"70.5","Cell RNA - CACO-2 [nTPM]":"62.4","Cell RNA - CAPAN-2 [nTPM]":"55.6","Cell RNA - Daudi [nTPM]":"141.6","Cell RNA - EFO-21 [nTPM]":"16.3","Cell RNA - fHDF\/TERT166 [nTPM]":"64.1","Cell RNA - GAMG [nTPM]":"102.6","Cell RNA - HaCaT [nTPM]":"51.7","Cell RNA - HAP1 [nTPM]":"126.1","Cell RNA - HBEC3-KT [nTPM]":"47.7","Cell RNA - HBF TERT88 [nTPM]":"100.9","Cell RNA - HDLM-2 [nTPM]":"80.3","Cell RNA - HEK 293 [nTPM]":"63.8","Cell RNA - HEL [nTPM]":"84.4","Cell RNA - HeLa [nTPM]":"89.3","Cell RNA - Hep G2 [nTPM]":"54.3","Cell RNA - HHSteC [nTPM]":"57.9","Cell RNA - HL-60 [nTPM]":"128.8","Cell RNA - HMC-1 [nTPM]":"68.5","Cell RNA - HSkMC [nTPM]":"39.6","Cell RNA - hTCEpi [nTPM]":"45.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"83.2","Cell RNA - hTERT-HME1 [nTPM]":"101.6","Cell RNA - hTERT-RPE1 [nTPM]":"50.4","Cell RNA - HUVEC TERT2 [nTPM]":"54.5","Cell RNA - JURKAT [nTPM]":"75.9","Cell RNA - K-562 [nTPM]":"149.9","Cell RNA - Karpas-707 [nTPM]":"86.4","Cell RNA - LHCN-M2 [nTPM]":"76.7","Cell RNA - MCF7 [nTPM]":"71.7","Cell RNA - MOLT-4 [nTPM]":"132.8","Cell RNA - NB-4 [nTPM]":"59.1","Cell RNA - NTERA-2 [nTPM]":"66.7","Cell RNA - OE19 [nTPM]":"57.6","Cell RNA - PC-3 [nTPM]":"56.2","Cell RNA - REH [nTPM]":"133.1","Cell RNA - RH-30 [nTPM]":"89.9","Cell RNA - RPMI-8226 [nTPM]":"94.5","Cell RNA - RPTEC TERT1 [nTPM]":"38.5","Cell RNA - RT4 [nTPM]":"58.2","Cell RNA - SCLC-21H [nTPM]":"102.4","Cell RNA - SH-SY5Y [nTPM]":"87.2","Cell RNA - SiHa [nTPM]":"102.1","Cell RNA - SK-BR-3 [nTPM]":"112.4","Cell RNA - SK-MEL-30 [nTPM]":"59.8","Cell RNA - SuSa [nTPM]":"87.1","Cell RNA - T-47d [nTPM]":"69.1","Cell RNA - THP-1 [nTPM]":"63.6","Cell RNA - TIME [nTPM]":"64.4","Cell RNA - U-138 MG [nTPM]":"116.1","Cell RNA - U-2 OS [nTPM]":"66.5","Cell RNA - U-2197 [nTPM]":"70.6","Cell RNA - U-251 MG [nTPM]":"123.2","Cell RNA - U-266\/70 [nTPM]":"49.7","Cell RNA - U-266\/84 [nTPM]":"84.7","Cell RNA - U-698 [nTPM]":"235.7","Cell RNA - U-87 MG [nTPM]":"65.9","Cell RNA - U-937 [nTPM]":"119.1","Cell RNA - WM-115 [nTPM]":"107.7","Blood RNA - basophil [nTPM]":"4.0","Blood RNA - classical monocyte [nTPM]":"1.5","Blood RNA - eosinophil [nTPM]":"1.0","Blood RNA - gdT-cell [nTPM]":"3.0","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"2.6","Blood RNA - memory B-cell [nTPM]":"1.2","Blood RNA - memory CD4 T-cell [nTPM]":"2.3","Blood RNA - memory CD8 T-cell [nTPM]":"2.2","Blood RNA - myeloid DC [nTPM]":"1.1","Blood RNA - naive B-cell [nTPM]":"2.5","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"2.8","Blood RNA - non-classical monocyte [nTPM]":"0.8","Blood RNA - plasmacytoid DC [nTPM]":"3.1","Blood RNA - T-reg [nTPM]":"2.5","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"24.1","Brain RNA - basal ganglia [nTPM]":"28.3","Brain RNA - cerebellum [nTPM]":"28.6","Brain RNA - cerebral cortex [nTPM]":"25.2","Brain RNA - hippocampal formation [nTPM]":"21.9","Brain RNA - hypothalamus [nTPM]":"26.9","Brain RNA - medulla oblongata [nTPM]":"25.1","Brain RNA - midbrain [nTPM]":"26.5","Brain RNA - pons [nTPM]":"24.7","Brain RNA - spinal cord [nTPM]":"23.8","Brain RNA - thalamus [nTPM]":"25.5","Brain RNA - white matter [nTPM]":"29.1","Single Cell Type RNA - Adipocytes [nTPM]":"46.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"76.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"129.8","Single Cell Type RNA - Astrocytes [nTPM]":"28.7","Single Cell Type RNA - B-cells [nTPM]":"52.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"29.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"34.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"38.1","Single Cell Type RNA - Bipolar cells [nTPM]":"69.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"28.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"81.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"59.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"43.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"57.3","Single Cell Type RNA - dendritic cells [nTPM]":"50.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"33.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"35.5","Single Cell Type RNA - Early spermatids [nTPM]":"8.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"47.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"72.2","Single Cell Type RNA - Endothelial cells [nTPM]":"53.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"34.7","Single Cell Type RNA - Erythroid cells [nTPM]":"89.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"35.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"59.6","Single Cell Type RNA - Fibroblasts [nTPM]":"58.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"34.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"52.6","Single Cell Type RNA - granulocytes [nTPM]":"51.8","Single Cell Type RNA - Granulosa cells [nTPM]":"59.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"34.6","Single Cell Type RNA - Hepatocytes [nTPM]":"59.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"33.0","Single Cell Type RNA - Horizontal cells [nTPM]":"60.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"35.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"34.6","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"33.4","Single Cell Type RNA - Langerhans cells [nTPM]":"24.8","Single Cell Type RNA - Late spermatids [nTPM]":"12.5","Single Cell Type RNA - Leydig cells [nTPM]":"61.2","Single Cell Type RNA - Macrophages [nTPM]":"38.7","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"34.7","Single Cell Type RNA - monocytes [nTPM]":"47.3","Single Cell Type RNA - Muller glia cells [nTPM]":"54.4","Single Cell Type RNA - NK-cells [nTPM]":"61.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"28.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"43.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"26.5","Single Cell Type RNA - Paneth cells [nTPM]":"13.6","Single Cell Type RNA - Peritubular cells [nTPM]":"76.3","Single Cell Type RNA - Plasma cells [nTPM]":"65.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"40.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"25.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"49.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"53.8","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"67.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"57.5","Single Cell Type RNA - Spermatocytes [nTPM]":"75.7","Single Cell Type RNA - Spermatogonia [nTPM]":"127.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"47.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"25.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"34.6","Single Cell Type RNA - T-cells [nTPM]":"56.5","Single Cell Type RNA - Theca cells [nTPM]":"46.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"43.3","Single Cell Type RNA - Urothelial cells [nTPM]":"35.2"},{"Gene":"BCAP31","Gene synonym":["6C6-Ag","BAP31","CDM","DXS1357E"],"Ensembl":"ENSG00000185825","Gene description":"B cell receptor associated protein 31","Uniprot":["P51572"],"Chromosome":"X","Position":"153700492-153724565","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","ER-Golgi transport","Host-virus interaction","Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Deafness","Dystonia","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003906","CAB015350","CAB015424"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB015350":"AB_2243544","CAB015424":"AB_781567","HPA003906":"AB_1078270"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.87e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Tissue RNA - adipose tissue [nTPM]":"294.1","Tissue RNA - adrenal gland [nTPM]":"213.9","Tissue RNA - amygdala [nTPM]":"171.5","Tissue RNA - appendix [nTPM]":"100.9","Tissue RNA - basal ganglia [nTPM]":"175.5","Tissue RNA - bone marrow [nTPM]":"151.3","Tissue RNA - breast [nTPM]":"210.9","Tissue RNA - cerebellum [nTPM]":"171.8","Tissue RNA - cerebral cortex [nTPM]":"213.9","Tissue RNA - cervix [nTPM]":"139.5","Tissue RNA - choroid plexus [nTPM]":"202.5","Tissue RNA - colon [nTPM]":"157.7","Tissue RNA - duodenum [nTPM]":"133.3","Tissue RNA - endometrium 1 [nTPM]":"127.4","Tissue RNA - epididymis [nTPM]":"228.9","Tissue RNA - esophagus [nTPM]":"214.0","Tissue RNA - fallopian tube [nTPM]":"151.0","Tissue RNA - gallbladder [nTPM]":"118.0","Tissue RNA - heart muscle [nTPM]":"123.5","Tissue RNA - hippocampal formation [nTPM]":"183.0","Tissue RNA - hypothalamus [nTPM]":"192.1","Tissue RNA - kidney [nTPM]":"160.7","Tissue RNA - liver [nTPM]":"185.5","Tissue RNA - lung [nTPM]":"144.5","Tissue RNA - lymph node [nTPM]":"111.8","Tissue RNA - medulla oblongata [nTPM]":"190.8","Tissue RNA - midbrain [nTPM]":"187.5","Tissue RNA - ovary [nTPM]":"130.9","Tissue RNA - pancreas [nTPM]":"266.4","Tissue RNA - parathyroid gland [nTPM]":"193.7","Tissue RNA - pituitary gland [nTPM]":"123.5","Tissue RNA - placenta [nTPM]":"143.3","Tissue RNA - pons [nTPM]":"195.3","Tissue RNA - prostate [nTPM]":"154.6","Tissue RNA - rectum [nTPM]":"166.5","Tissue RNA - retina [nTPM]":"63.9","Tissue RNA - salivary gland [nTPM]":"179.7","Tissue RNA - seminal vesicle [nTPM]":"177.7","Tissue RNA - skeletal muscle [nTPM]":"81.9","Tissue RNA - skin 1 [nTPM]":"187.3","Tissue RNA - small intestine [nTPM]":"143.8","Tissue RNA - smooth muscle [nTPM]":"155.0","Tissue RNA - spinal cord [nTPM]":"183.4","Tissue RNA - spleen [nTPM]":"138.5","Tissue RNA - stomach 1 [nTPM]":"129.3","Tissue RNA - testis [nTPM]":"117.3","Tissue RNA - thalamus [nTPM]":"186.9","Tissue RNA - thymus [nTPM]":"99.7","Tissue RNA - thyroid gland [nTPM]":"161.4","Tissue RNA - tongue [nTPM]":"75.5","Tissue RNA - tonsil [nTPM]":"134.6","Tissue RNA - urinary bladder [nTPM]":"177.9","Tissue RNA - vagina [nTPM]":"145.8","Tissue RNA - white matter [nTPM]":"185.0","Cell RNA - A-431 [nTPM]":"505.5","Cell RNA - A549 [nTPM]":"482.4","Cell RNA - AF22 [nTPM]":"128.0","Cell RNA - AN3-CA [nTPM]":"650.6","Cell RNA - ASC diff [nTPM]":"593.8","Cell RNA - ASC TERT1 [nTPM]":"179.1","Cell RNA - BEWO [nTPM]":"295.3","Cell RNA - BJ [nTPM]":"269.9","Cell RNA - BJ hTERT+ [nTPM]":"287.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"291.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"371.6","Cell RNA - CACO-2 [nTPM]":"386.8","Cell RNA - CAPAN-2 [nTPM]":"361.9","Cell RNA - Daudi [nTPM]":"315.9","Cell RNA - EFO-21 [nTPM]":"1068.1","Cell RNA - fHDF\/TERT166 [nTPM]":"412.2","Cell RNA - GAMG [nTPM]":"373.9","Cell RNA - HaCaT [nTPM]":"506.8","Cell RNA - HAP1 [nTPM]":"337.3","Cell RNA - HBEC3-KT [nTPM]":"518.6","Cell RNA - HBF TERT88 [nTPM]":"221.0","Cell RNA - HDLM-2 [nTPM]":"152.8","Cell RNA - HEK 293 [nTPM]":"436.9","Cell RNA - HEL [nTPM]":"198.4","Cell RNA - HeLa [nTPM]":"350.4","Cell RNA - Hep G2 [nTPM]":"323.3","Cell RNA - HHSteC [nTPM]":"276.4","Cell RNA - HL-60 [nTPM]":"335.1","Cell RNA - HMC-1 [nTPM]":"373.2","Cell RNA - HSkMC [nTPM]":"233.8","Cell RNA - hTCEpi [nTPM]":"454.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"282.3","Cell RNA - hTERT-HME1 [nTPM]":"330.1","Cell RNA - hTERT-RPE1 [nTPM]":"298.4","Cell RNA - HUVEC TERT2 [nTPM]":"372.6","Cell RNA - JURKAT [nTPM]":"172.0","Cell RNA - K-562 [nTPM]":"268.0","Cell RNA - Karpas-707 [nTPM]":"528.3","Cell RNA - LHCN-M2 [nTPM]":"332.7","Cell RNA - MCF7 [nTPM]":"535.3","Cell RNA - MOLT-4 [nTPM]":"187.3","Cell RNA - NB-4 [nTPM]":"402.5","Cell RNA - NTERA-2 [nTPM]":"145.8","Cell RNA - OE19 [nTPM]":"704.6","Cell RNA - PC-3 [nTPM]":"431.7","Cell RNA - REH [nTPM]":"207.5","Cell RNA - RH-30 [nTPM]":"152.8","Cell RNA - RPMI-8226 [nTPM]":"693.2","Cell RNA - RPTEC TERT1 [nTPM]":"459.3","Cell RNA - RT4 [nTPM]":"546.8","Cell RNA - SCLC-21H [nTPM]":"173.3","Cell RNA - SH-SY5Y [nTPM]":"241.8","Cell RNA - SiHa [nTPM]":"111.8","Cell RNA - SK-BR-3 [nTPM]":"520.6","Cell RNA - SK-MEL-30 [nTPM]":"350.0","Cell RNA - SuSa [nTPM]":"200.3","Cell RNA - T-47d [nTPM]":"196.2","Cell RNA - THP-1 [nTPM]":"320.2","Cell RNA - TIME [nTPM]":"380.0","Cell RNA - U-138 MG [nTPM]":"248.9","Cell RNA - U-2 OS [nTPM]":"234.7","Cell RNA - U-2197 [nTPM]":"338.9","Cell RNA - U-251 MG [nTPM]":"495.1","Cell RNA - U-266\/70 [nTPM]":"518.0","Cell RNA - U-266\/84 [nTPM]":"1120.1","Cell RNA - U-698 [nTPM]":"397.3","Cell RNA - U-87 MG [nTPM]":"460.9","Cell RNA - U-937 [nTPM]":"402.6","Cell RNA - WM-115 [nTPM]":"223.7","Blood RNA - basophil [nTPM]":"630.5","Blood RNA - classical monocyte [nTPM]":"484.2","Blood RNA - eosinophil [nTPM]":"489.1","Blood RNA - gdT-cell [nTPM]":"507.5","Blood RNA - intermediate monocyte [nTPM]":"535.7","Blood RNA - MAIT T-cell [nTPM]":"454.7","Blood RNA - memory B-cell [nTPM]":"436.1","Blood RNA - memory CD4 T-cell [nTPM]":"504.5","Blood RNA - memory CD8 T-cell [nTPM]":"507.4","Blood RNA - myeloid DC [nTPM]":"420.7","Blood RNA - naive B-cell [nTPM]":"463.6","Blood RNA - naive CD4 T-cell [nTPM]":"439.1","Blood RNA - naive CD8 T-cell [nTPM]":"474.7","Blood RNA - neutrophil [nTPM]":"624.5","Blood RNA - NK-cell [nTPM]":"449.8","Blood RNA - non-classical monocyte [nTPM]":"632.3","Blood RNA - plasmacytoid DC [nTPM]":"666.9","Blood RNA - T-reg [nTPM]":"457.1","Blood RNA - total PBMC [nTPM]":"1110.8","Brain RNA - amygdala [nTPM]":"171.5","Brain RNA - basal ganglia [nTPM]":"175.5","Brain RNA - cerebellum [nTPM]":"171.8","Brain RNA - cerebral cortex [nTPM]":"213.9","Brain RNA - hippocampal formation [nTPM]":"183.0","Brain RNA - hypothalamus [nTPM]":"192.1","Brain RNA - medulla oblongata [nTPM]":"190.8","Brain RNA - midbrain [nTPM]":"187.5","Brain RNA - pons [nTPM]":"195.3","Brain RNA - spinal cord [nTPM]":"183.4","Brain RNA - thalamus [nTPM]":"186.9","Brain RNA - white matter [nTPM]":"185.0","Single Cell Type RNA - Adipocytes [nTPM]":"184.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"112.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"114.1","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"97.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"141.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"232.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"374.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"172.4","Single Cell Type RNA - Bipolar cells [nTPM]":"53.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"127.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"165.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"60.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"134.4","Single Cell Type RNA - Club cells [nTPM]":"222.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"128.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"467.5","Single Cell Type RNA - dendritic cells [nTPM]":"113.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"194.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"37.2","Single Cell Type RNA - Ductal cells [nTPM]":"252.4","Single Cell Type RNA - Early spermatids [nTPM]":"7.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"99.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"70.1","Single Cell Type RNA - Endothelial cells [nTPM]":"165.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"103.2","Single Cell Type RNA - Erythroid cells [nTPM]":"59.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"210.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"444.8","Single Cell Type RNA - Fibroblasts [nTPM]":"103.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"78.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"103.9","Single Cell Type RNA - granulocytes [nTPM]":"95.6","Single Cell Type RNA - Granulosa cells [nTPM]":"68.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"199.6","Single Cell Type RNA - Hepatocytes [nTPM]":"216.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"356.2","Single Cell Type RNA - Horizontal cells [nTPM]":"32.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"155.1","Single Cell Type RNA - Ionocytes [nTPM]":"244.1","Single Cell Type RNA - Kupffer cells [nTPM]":"148.4","Single Cell Type RNA - Langerhans cells [nTPM]":"125.6","Single Cell Type RNA - Late spermatids [nTPM]":"20.6","Single Cell Type RNA - Leydig cells [nTPM]":"105.3","Single Cell Type RNA - Macrophages [nTPM]":"166.2","Single Cell Type RNA - Melanocytes [nTPM]":"160.1","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"137.5","Single Cell Type RNA - Muller glia cells [nTPM]":"138.2","Single Cell Type RNA - NK-cells [nTPM]":"111.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"247.1","Single Cell Type RNA - Paneth cells [nTPM]":"187.4","Single Cell Type RNA - Peritubular cells [nTPM]":"98.9","Single Cell Type RNA - Plasma cells [nTPM]":"120.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"191.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"242.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"170.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"172.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"51.8","Single Cell Type RNA - Sertoli cells [nTPM]":"157.8","Single Cell Type RNA - Skeletal myocytes [nTPM]":"42.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"106.5","Single Cell Type RNA - Spermatocytes [nTPM]":"310.3","Single Cell Type RNA - Spermatogonia [nTPM]":"231.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"174.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"130.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"538.1","Single Cell Type RNA - T-cells [nTPM]":"114.6","Single Cell Type RNA - Theca cells [nTPM]":"120.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"187.0","Single Cell Type RNA - Urothelial cells [nTPM]":"260.4"},{"Gene":"BCKDHA","Gene synonym":["MSU","OVD1A"],"Ensembl":"ENSG00000248098","Gene description":"Branched chain keto acid dehydrogenase E1 subunit alpha","Uniprot":["P12694"],"Chromosome":"19","Position":"41397808-41425002","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Maple syrup urine disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"26.2","Gastric mucus-secreting cells":"23.4","Plasma cells":"25.0","Squamous epithelial cells":"27.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036640"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7700","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036640":"AB_10671964"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.37e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.33e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.27e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.66e-2"},"Tissue RNA - adipose tissue [nTPM]":"33.8","Tissue RNA - adrenal gland [nTPM]":"78.4","Tissue RNA - amygdala [nTPM]":"32.0","Tissue RNA - appendix [nTPM]":"19.3","Tissue RNA - basal ganglia [nTPM]":"35.5","Tissue RNA - bone marrow [nTPM]":"32.4","Tissue RNA - breast [nTPM]":"25.2","Tissue RNA - cerebellum [nTPM]":"37.0","Tissue RNA - cerebral cortex [nTPM]":"39.3","Tissue RNA - cervix [nTPM]":"24.6","Tissue RNA - choroid plexus [nTPM]":"37.0","Tissue RNA - colon [nTPM]":"20.9","Tissue RNA - duodenum [nTPM]":"19.9","Tissue RNA - endometrium 1 [nTPM]":"17.9","Tissue RNA - epididymis [nTPM]":"14.1","Tissue RNA - esophagus [nTPM]":"65.1","Tissue RNA - fallopian tube [nTPM]":"28.8","Tissue RNA - gallbladder [nTPM]":"15.4","Tissue RNA - heart muscle [nTPM]":"90.4","Tissue RNA - hippocampal formation [nTPM]":"32.5","Tissue RNA - hypothalamus [nTPM]":"35.1","Tissue RNA - kidney [nTPM]":"44.3","Tissue RNA - liver [nTPM]":"110.0","Tissue RNA - lung [nTPM]":"22.4","Tissue RNA - lymph node [nTPM]":"24.5","Tissue RNA - medulla oblongata [nTPM]":"34.4","Tissue RNA - midbrain [nTPM]":"33.8","Tissue RNA - ovary [nTPM]":"25.4","Tissue RNA - pancreas [nTPM]":"46.1","Tissue RNA - parathyroid gland [nTPM]":"56.3","Tissue RNA - pituitary gland [nTPM]":"24.0","Tissue RNA - placenta [nTPM]":"19.0","Tissue RNA - pons [nTPM]":"36.2","Tissue RNA - prostate [nTPM]":"23.8","Tissue RNA - rectum [nTPM]":"15.0","Tissue RNA - retina [nTPM]":"21.7","Tissue RNA - salivary gland [nTPM]":"40.9","Tissue RNA - seminal vesicle [nTPM]":"23.1","Tissue RNA - skeletal muscle [nTPM]":"110.0","Tissue RNA - skin 1 [nTPM]":"31.8","Tissue RNA - small intestine [nTPM]":"18.7","Tissue RNA - smooth muscle [nTPM]":"12.7","Tissue RNA - spinal cord [nTPM]":"33.9","Tissue RNA - spleen [nTPM]":"24.4","Tissue RNA - stomach 1 [nTPM]":"52.5","Tissue RNA - testis [nTPM]":"27.1","Tissue RNA - thalamus [nTPM]":"35.7","Tissue RNA - thymus [nTPM]":"27.0","Tissue RNA - thyroid gland [nTPM]":"41.7","Tissue RNA - tongue [nTPM]":"122.0","Tissue RNA - tonsil [nTPM]":"21.2","Tissue RNA - urinary bladder [nTPM]":"21.7","Tissue RNA - vagina [nTPM]":"31.9","Tissue RNA - white matter [nTPM]":"40.0","Cell RNA - A-431 [nTPM]":"42.7","Cell RNA - A549 [nTPM]":"75.1","Cell RNA - AF22 [nTPM]":"14.2","Cell RNA - AN3-CA [nTPM]":"44.1","Cell RNA - ASC diff [nTPM]":"22.2","Cell RNA - ASC TERT1 [nTPM]":"12.8","Cell RNA - BEWO [nTPM]":"17.1","Cell RNA - BJ [nTPM]":"11.9","Cell RNA - BJ hTERT+ [nTPM]":"25.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"29.9","Cell RNA - CACO-2 [nTPM]":"18.2","Cell RNA - CAPAN-2 [nTPM]":"36.0","Cell RNA - Daudi [nTPM]":"34.6","Cell RNA - EFO-21 [nTPM]":"23.7","Cell RNA - fHDF\/TERT166 [nTPM]":"15.1","Cell RNA - GAMG [nTPM]":"11.0","Cell RNA - HaCaT [nTPM]":"17.1","Cell RNA - HAP1 [nTPM]":"15.0","Cell RNA - HBEC3-KT [nTPM]":"25.9","Cell RNA - HBF TERT88 [nTPM]":"12.1","Cell RNA - HDLM-2 [nTPM]":"36.0","Cell RNA - HEK 293 [nTPM]":"41.0","Cell RNA - HEL [nTPM]":"27.1","Cell RNA - HeLa [nTPM]":"35.2","Cell RNA - Hep G2 [nTPM]":"21.3","Cell RNA - HHSteC [nTPM]":"51.5","Cell RNA - HL-60 [nTPM]":"25.5","Cell RNA - HMC-1 [nTPM]":"17.7","Cell RNA - HSkMC [nTPM]":"27.6","Cell RNA - hTCEpi [nTPM]":"37.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.9","Cell RNA - hTERT-HME1 [nTPM]":"38.2","Cell RNA - hTERT-RPE1 [nTPM]":"36.0","Cell RNA - HUVEC TERT2 [nTPM]":"45.0","Cell RNA - JURKAT [nTPM]":"50.9","Cell RNA - K-562 [nTPM]":"25.9","Cell RNA - Karpas-707 [nTPM]":"68.9","Cell RNA - LHCN-M2 [nTPM]":"17.6","Cell RNA - MCF7 [nTPM]":"41.5","Cell RNA - MOLT-4 [nTPM]":"28.0","Cell RNA - NB-4 [nTPM]":"20.0","Cell RNA - NTERA-2 [nTPM]":"12.8","Cell RNA - OE19 [nTPM]":"61.1","Cell RNA - PC-3 [nTPM]":"21.1","Cell RNA - REH [nTPM]":"27.1","Cell RNA - RH-30 [nTPM]":"22.8","Cell RNA - RPMI-8226 [nTPM]":"89.6","Cell RNA - RPTEC TERT1 [nTPM]":"29.8","Cell RNA - RT4 [nTPM]":"19.8","Cell RNA - SCLC-21H [nTPM]":"32.5","Cell RNA - SH-SY5Y [nTPM]":"38.6","Cell RNA - SiHa [nTPM]":"39.6","Cell RNA - SK-BR-3 [nTPM]":"84.7","Cell RNA - SK-MEL-30 [nTPM]":"34.1","Cell RNA - SuSa [nTPM]":"12.1","Cell RNA - T-47d [nTPM]":"45.4","Cell RNA - THP-1 [nTPM]":"81.0","Cell RNA - TIME [nTPM]":"29.3","Cell RNA - U-138 MG [nTPM]":"22.2","Cell RNA - U-2 OS [nTPM]":"23.0","Cell RNA - U-2197 [nTPM]":"12.0","Cell RNA - U-251 MG [nTPM]":"22.0","Cell RNA - U-266\/70 [nTPM]":"131.9","Cell RNA - U-266\/84 [nTPM]":"55.1","Cell RNA - U-698 [nTPM]":"34.1","Cell RNA - U-87 MG [nTPM]":"81.8","Cell RNA - U-937 [nTPM]":"56.6","Cell RNA - WM-115 [nTPM]":"24.6","Blood RNA - basophil [nTPM]":"61.4","Blood RNA - classical monocyte [nTPM]":"149.4","Blood RNA - eosinophil [nTPM]":"59.7","Blood RNA - gdT-cell [nTPM]":"49.5","Blood RNA - intermediate monocyte [nTPM]":"123.9","Blood RNA - MAIT T-cell [nTPM]":"56.7","Blood RNA - memory B-cell [nTPM]":"46.0","Blood RNA - memory CD4 T-cell [nTPM]":"47.0","Blood RNA - memory CD8 T-cell [nTPM]":"49.1","Blood RNA - myeloid DC [nTPM]":"154.6","Blood RNA - naive B-cell [nTPM]":"49.5","Blood RNA - naive CD4 T-cell [nTPM]":"43.2","Blood RNA - naive CD8 T-cell [nTPM]":"44.9","Blood RNA - neutrophil [nTPM]":"46.4","Blood RNA - NK-cell [nTPM]":"82.4","Blood RNA - non-classical monocyte [nTPM]":"95.5","Blood RNA - plasmacytoid DC [nTPM]":"62.6","Blood RNA - T-reg [nTPM]":"63.9","Blood RNA - total PBMC [nTPM]":"125.6","Brain RNA - amygdala [nTPM]":"32.0","Brain RNA - basal ganglia [nTPM]":"35.5","Brain RNA - cerebellum [nTPM]":"37.0","Brain RNA - cerebral cortex [nTPM]":"39.3","Brain RNA - hippocampal formation [nTPM]":"32.5","Brain RNA - hypothalamus [nTPM]":"35.1","Brain RNA - medulla oblongata [nTPM]":"34.4","Brain RNA - midbrain [nTPM]":"33.8","Brain RNA - pons [nTPM]":"36.2","Brain RNA - spinal cord [nTPM]":"33.9","Brain RNA - thalamus [nTPM]":"35.7","Brain RNA - white matter [nTPM]":"40.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.1","Single Cell Type RNA - Astrocytes [nTPM]":"4.9","Single Cell Type RNA - B-cells [nTPM]":"10.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"5.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - dendritic cells [nTPM]":"0.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"14.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.6","Single Cell Type RNA - Endothelial cells [nTPM]":"2.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.1","Single Cell Type RNA - Erythroid cells [nTPM]":"15.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.7","Single Cell Type RNA - Fibroblasts [nTPM]":"3.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"2.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.6","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"2.2","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"6.6","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"12.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.4","Single Cell Type RNA - Paneth cells [nTPM]":"3.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"25.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.6","Single Cell Type RNA - Spermatocytes [nTPM]":"1.8","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"27.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.1","Single Cell Type RNA - T-cells [nTPM]":"6.3","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"BCKDHB","Gene synonym":[],"Ensembl":"ENSG00000083123","Gene description":"Branched chain keto acid dehydrogenase E1 subunit beta","Uniprot":["P21953"],"Chromosome":"6","Position":"80106647-80346270","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Maple syrup urine disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"78.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"296.5","Early spermatids":"110.9","Inhibitory neurons":"94.9","Oligodendrocyte precursor cells":"98.5","Oligodendrocytes":"101.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031580","HPA031956"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Mitochondria"],"Secretome location":"Intracellular and membrane","CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm","Nucleoli"],"Antibody RRID":{"HPA031580":"AB_10696054","HPA031956":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.50e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.37e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.54e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Tissue RNA - adipose tissue [nTPM]":"19.7","Tissue RNA - adrenal gland [nTPM]":"10.7","Tissue RNA - amygdala [nTPM]":"7.3","Tissue RNA - appendix [nTPM]":"7.6","Tissue RNA - basal ganglia [nTPM]":"8.3","Tissue RNA - bone marrow [nTPM]":"8.2","Tissue RNA - breast [nTPM]":"22.3","Tissue RNA - cerebellum [nTPM]":"11.5","Tissue RNA - cerebral cortex [nTPM]":"7.8","Tissue RNA - cervix [nTPM]":"11.7","Tissue RNA - choroid plexus [nTPM]":"11.6","Tissue RNA - colon [nTPM]":"22.5","Tissue RNA - duodenum [nTPM]":"11.5","Tissue RNA - endometrium 1 [nTPM]":"9.2","Tissue RNA - epididymis [nTPM]":"7.1","Tissue RNA - esophagus [nTPM]":"10.3","Tissue RNA - fallopian tube [nTPM]":"11.5","Tissue RNA - gallbladder [nTPM]":"7.8","Tissue RNA - heart muscle [nTPM]":"18.8","Tissue RNA - hippocampal formation [nTPM]":"8.8","Tissue RNA - hypothalamus [nTPM]":"7.0","Tissue RNA - kidney [nTPM]":"31.8","Tissue RNA - liver [nTPM]":"78.4","Tissue RNA - lung [nTPM]":"7.3","Tissue RNA - lymph node [nTPM]":"8.8","Tissue RNA - medulla oblongata [nTPM]":"10.7","Tissue RNA - midbrain [nTPM]":"9.2","Tissue RNA - ovary [nTPM]":"14.6","Tissue RNA - pancreas [nTPM]":"12.9","Tissue RNA - parathyroid gland [nTPM]":"19.7","Tissue RNA - pituitary gland [nTPM]":"7.2","Tissue RNA - placenta [nTPM]":"4.8","Tissue RNA - pons [nTPM]":"13.1","Tissue RNA - prostate [nTPM]":"15.9","Tissue RNA - rectum [nTPM]":"20.7","Tissue RNA - retina [nTPM]":"7.9","Tissue RNA - salivary gland [nTPM]":"26.6","Tissue RNA - seminal vesicle [nTPM]":"11.3","Tissue RNA - skeletal muscle [nTPM]":"10.9","Tissue RNA - skin 1 [nTPM]":"8.5","Tissue RNA - small intestine [nTPM]":"12.4","Tissue RNA - smooth muscle [nTPM]":"9.4","Tissue RNA - spinal cord [nTPM]":"11.8","Tissue RNA - spleen [nTPM]":"6.3","Tissue RNA - stomach 1 [nTPM]":"17.6","Tissue RNA - testis [nTPM]":"13.1","Tissue RNA - thalamus [nTPM]":"8.7","Tissue RNA - thymus [nTPM]":"9.1","Tissue RNA - thyroid gland [nTPM]":"15.5","Tissue RNA - tongue [nTPM]":"15.3","Tissue RNA - tonsil [nTPM]":"9.1","Tissue RNA - urinary bladder [nTPM]":"11.2","Tissue RNA - vagina [nTPM]":"7.6","Tissue RNA - white matter [nTPM]":"16.0","Cell RNA - A-431 [nTPM]":"13.8","Cell RNA - A549 [nTPM]":"5.1","Cell RNA - AF22 [nTPM]":"18.8","Cell RNA - AN3-CA [nTPM]":"25.3","Cell RNA - ASC diff [nTPM]":"18.6","Cell RNA - ASC TERT1 [nTPM]":"16.1","Cell RNA - BEWO [nTPM]":"14.9","Cell RNA - BJ [nTPM]":"9.7","Cell RNA - BJ hTERT+ [nTPM]":"19.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.0","Cell RNA - CACO-2 [nTPM]":"8.3","Cell RNA - CAPAN-2 [nTPM]":"18.5","Cell RNA - Daudi [nTPM]":"38.9","Cell RNA - EFO-21 [nTPM]":"10.1","Cell RNA - fHDF\/TERT166 [nTPM]":"23.1","Cell RNA - GAMG [nTPM]":"18.0","Cell RNA - HaCaT [nTPM]":"13.6","Cell RNA - HAP1 [nTPM]":"10.6","Cell RNA - HBEC3-KT [nTPM]":"12.7","Cell RNA - HBF TERT88 [nTPM]":"21.5","Cell RNA - HDLM-2 [nTPM]":"48.8","Cell RNA - HEK 293 [nTPM]":"15.6","Cell RNA - HEL [nTPM]":"19.4","Cell RNA - HeLa [nTPM]":"12.6","Cell RNA - Hep G2 [nTPM]":"11.3","Cell RNA - HHSteC [nTPM]":"20.7","Cell RNA - HL-60 [nTPM]":"27.7","Cell RNA - HMC-1 [nTPM]":"8.3","Cell RNA - HSkMC [nTPM]":"15.6","Cell RNA - hTCEpi [nTPM]":"12.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.7","Cell RNA - hTERT-HME1 [nTPM]":"13.3","Cell RNA - hTERT-RPE1 [nTPM]":"13.8","Cell RNA - HUVEC TERT2 [nTPM]":"18.6","Cell RNA - JURKAT [nTPM]":"29.8","Cell RNA - K-562 [nTPM]":"16.6","Cell RNA - Karpas-707 [nTPM]":"33.8","Cell RNA - LHCN-M2 [nTPM]":"35.0","Cell RNA - MCF7 [nTPM]":"7.6","Cell RNA - MOLT-4 [nTPM]":"10.3","Cell RNA - NB-4 [nTPM]":"16.3","Cell RNA - NTERA-2 [nTPM]":"14.0","Cell RNA - OE19 [nTPM]":"30.1","Cell RNA - PC-3 [nTPM]":"6.5","Cell RNA - REH [nTPM]":"25.5","Cell RNA - RH-30 [nTPM]":"58.3","Cell RNA - RPMI-8226 [nTPM]":"33.8","Cell RNA - RPTEC TERT1 [nTPM]":"43.2","Cell RNA - RT4 [nTPM]":"20.7","Cell RNA - SCLC-21H [nTPM]":"12.6","Cell RNA - SH-SY5Y [nTPM]":"17.8","Cell RNA - SiHa [nTPM]":"16.2","Cell RNA - SK-BR-3 [nTPM]":"13.4","Cell RNA - SK-MEL-30 [nTPM]":"9.9","Cell RNA - SuSa [nTPM]":"20.6","Cell RNA - T-47d [nTPM]":"17.3","Cell RNA - THP-1 [nTPM]":"21.1","Cell RNA - TIME [nTPM]":"8.0","Cell RNA - U-138 MG [nTPM]":"9.2","Cell RNA - U-2 OS [nTPM]":"6.3","Cell RNA - U-2197 [nTPM]":"8.5","Cell RNA - U-251 MG [nTPM]":"13.0","Cell RNA - U-266\/70 [nTPM]":"24.0","Cell RNA - U-266\/84 [nTPM]":"25.2","Cell RNA - U-698 [nTPM]":"12.9","Cell RNA - U-87 MG [nTPM]":"11.3","Cell RNA - U-937 [nTPM]":"20.4","Cell RNA - WM-115 [nTPM]":"14.2","Blood RNA - basophil [nTPM]":"3.4","Blood RNA - classical monocyte [nTPM]":"4.2","Blood RNA - eosinophil [nTPM]":"1.0","Blood RNA - gdT-cell [nTPM]":"10.1","Blood RNA - intermediate monocyte [nTPM]":"5.1","Blood RNA - MAIT T-cell [nTPM]":"13.3","Blood RNA - memory B-cell [nTPM]":"10.6","Blood RNA - memory CD4 T-cell [nTPM]":"8.3","Blood RNA - memory CD8 T-cell [nTPM]":"8.5","Blood RNA - myeloid DC [nTPM]":"8.3","Blood RNA - naive B-cell [nTPM]":"12.7","Blood RNA - naive CD4 T-cell [nTPM]":"11.0","Blood RNA - naive CD8 T-cell [nTPM]":"11.6","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"17.4","Blood RNA - non-classical monocyte [nTPM]":"5.9","Blood RNA - plasmacytoid DC [nTPM]":"12.9","Blood RNA - T-reg [nTPM]":"20.3","Blood RNA - total PBMC [nTPM]":"6.1","Brain RNA - amygdala [nTPM]":"7.3","Brain RNA - basal ganglia [nTPM]":"8.3","Brain RNA - cerebellum [nTPM]":"11.5","Brain RNA - cerebral cortex [nTPM]":"7.8","Brain RNA - hippocampal formation [nTPM]":"8.8","Brain RNA - hypothalamus [nTPM]":"7.0","Brain RNA - medulla oblongata [nTPM]":"10.7","Brain RNA - midbrain [nTPM]":"9.2","Brain RNA - pons [nTPM]":"13.1","Brain RNA - spinal cord [nTPM]":"11.8","Brain RNA - thalamus [nTPM]":"8.7","Brain RNA - white matter [nTPM]":"16.0","Single Cell Type RNA - Adipocytes [nTPM]":"8.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.0","Single Cell Type RNA - Astrocytes [nTPM]":"296.5","Single Cell Type RNA - B-cells [nTPM]":"11.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Bipolar cells [nTPM]":"7.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"29.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"18.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"17.0","Single Cell Type RNA - dendritic cells [nTPM]":"9.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"27.4","Single Cell Type RNA - Ductal cells [nTPM]":"8.2","Single Cell Type RNA - Early spermatids [nTPM]":"110.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.3","Single Cell Type RNA - Endothelial cells [nTPM]":"8.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.0","Single Cell Type RNA - Erythroid cells [nTPM]":"10.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"72.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.3","Single Cell Type RNA - Fibroblasts [nTPM]":"13.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.6","Single Cell Type RNA - granulocytes [nTPM]":"16.5","Single Cell Type RNA - Granulosa cells [nTPM]":"19.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"66.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.2","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"94.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.3","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"9.1","Single Cell Type RNA - Langerhans cells [nTPM]":"9.0","Single Cell Type RNA - Late spermatids [nTPM]":"13.7","Single Cell Type RNA - Leydig cells [nTPM]":"8.7","Single Cell Type RNA - Macrophages [nTPM]":"5.4","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"59.0","Single Cell Type RNA - monocytes [nTPM]":"7.3","Single Cell Type RNA - Muller glia cells [nTPM]":"15.5","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"98.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"101.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.4","Single Cell Type RNA - Paneth cells [nTPM]":"10.4","Single Cell Type RNA - Peritubular cells [nTPM]":"8.6","Single Cell Type RNA - Plasma cells [nTPM]":"8.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"33.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.4","Single Cell Type RNA - Spermatocytes [nTPM]":"15.2","Single Cell Type RNA - Spermatogonia [nTPM]":"5.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.4","Single Cell Type RNA - T-cells [nTPM]":"9.9","Single Cell Type RNA - Theca cells [nTPM]":"15.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.4","Single Cell Type RNA - Urothelial cells [nTPM]":"10.9"},{"Gene":"BCKDK","Gene synonym":[],"Ensembl":"ENSG00000103507","Gene description":"Branched chain keto acid dehydrogenase kinase","Uniprot":["O14874"],"Chromosome":"16","Position":"31106107-31112791","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":["Autism","Autism spectrum disorder","Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"95.9","granulocytes":"89.7","monocytes":"115.0"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017995","HPA056067"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA017995":"AB_1845309","HPA056067":"AB_2683024"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-2"},"Tissue RNA - adipose tissue [nTPM]":"32.3","Tissue RNA - adrenal gland [nTPM]":"56.4","Tissue RNA - amygdala [nTPM]":"18.4","Tissue RNA - appendix [nTPM]":"19.2","Tissue RNA - basal ganglia [nTPM]":"18.6","Tissue RNA - bone marrow [nTPM]":"14.5","Tissue RNA - breast [nTPM]":"29.0","Tissue RNA - cerebellum [nTPM]":"17.4","Tissue RNA - cerebral cortex [nTPM]":"23.8","Tissue RNA - cervix [nTPM]":"25.1","Tissue RNA - choroid plexus [nTPM]":"18.0","Tissue RNA - colon [nTPM]":"31.4","Tissue RNA - duodenum [nTPM]":"16.0","Tissue RNA - endometrium 1 [nTPM]":"27.7","Tissue RNA - epididymis [nTPM]":"16.7","Tissue RNA - esophagus [nTPM]":"29.4","Tissue RNA - fallopian tube [nTPM]":"24.8","Tissue RNA - gallbladder [nTPM]":"17.9","Tissue RNA - heart muscle [nTPM]":"78.6","Tissue RNA - hippocampal formation [nTPM]":"18.8","Tissue RNA - hypothalamus [nTPM]":"17.8","Tissue RNA - kidney [nTPM]":"43.8","Tissue RNA - liver [nTPM]":"76.4","Tissue RNA - lung [nTPM]":"21.7","Tissue RNA - lymph node [nTPM]":"15.6","Tissue RNA - medulla oblongata [nTPM]":"20.6","Tissue RNA - midbrain [nTPM]":"20.7","Tissue RNA - ovary [nTPM]":"27.5","Tissue RNA - pancreas [nTPM]":"70.5","Tissue RNA - parathyroid gland [nTPM]":"22.9","Tissue RNA - pituitary gland [nTPM]":"16.4","Tissue RNA - placenta [nTPM]":"15.3","Tissue RNA - pons [nTPM]":"19.3","Tissue RNA - prostate [nTPM]":"29.3","Tissue RNA - rectum [nTPM]":"12.5","Tissue RNA - retina [nTPM]":"6.3","Tissue RNA - salivary gland [nTPM]":"47.0","Tissue RNA - seminal vesicle [nTPM]":"21.8","Tissue RNA - skeletal muscle [nTPM]":"81.3","Tissue RNA - skin 1 [nTPM]":"45.4","Tissue RNA - small intestine [nTPM]":"24.1","Tissue RNA - smooth muscle [nTPM]":"19.5","Tissue RNA - spinal cord [nTPM]":"17.1","Tissue RNA - spleen [nTPM]":"30.2","Tissue RNA - stomach 1 [nTPM]":"42.0","Tissue RNA - testis [nTPM]":"17.4","Tissue RNA - thalamus [nTPM]":"18.5","Tissue RNA - thymus [nTPM]":"9.8","Tissue RNA - thyroid gland [nTPM]":"22.4","Tissue RNA - tongue [nTPM]":"69.7","Tissue RNA - tonsil [nTPM]":"13.6","Tissue RNA - urinary bladder [nTPM]":"30.2","Tissue RNA - vagina [nTPM]":"24.6","Tissue RNA - white matter [nTPM]":"17.5","Cell RNA - A-431 [nTPM]":"47.5","Cell RNA - A549 [nTPM]":"49.1","Cell RNA - AF22 [nTPM]":"27.1","Cell RNA - AN3-CA [nTPM]":"41.8","Cell RNA - ASC diff [nTPM]":"32.8","Cell RNA - ASC TERT1 [nTPM]":"32.5","Cell RNA - BEWO [nTPM]":"31.1","Cell RNA - BJ [nTPM]":"40.4","Cell RNA - BJ hTERT+ [nTPM]":"46.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"57.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"55.9","Cell RNA - CACO-2 [nTPM]":"32.1","Cell RNA - CAPAN-2 [nTPM]":"29.1","Cell RNA - Daudi [nTPM]":"41.5","Cell RNA - EFO-21 [nTPM]":"58.9","Cell RNA - fHDF\/TERT166 [nTPM]":"47.5","Cell RNA - GAMG [nTPM]":"28.0","Cell RNA - HaCaT [nTPM]":"31.4","Cell RNA - HAP1 [nTPM]":"19.3","Cell RNA - HBEC3-KT [nTPM]":"65.6","Cell RNA - HBF TERT88 [nTPM]":"36.5","Cell RNA - HDLM-2 [nTPM]":"34.4","Cell RNA - HEK 293 [nTPM]":"60.1","Cell RNA - HEL [nTPM]":"45.2","Cell RNA - HeLa [nTPM]":"32.6","Cell RNA - Hep G2 [nTPM]":"59.5","Cell RNA - HHSteC [nTPM]":"57.5","Cell RNA - HL-60 [nTPM]":"23.5","Cell RNA - HMC-1 [nTPM]":"41.9","Cell RNA - HSkMC [nTPM]":"48.3","Cell RNA - hTCEpi [nTPM]":"26.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"49.2","Cell RNA - hTERT-HME1 [nTPM]":"40.6","Cell RNA - hTERT-RPE1 [nTPM]":"52.6","Cell RNA - HUVEC TERT2 [nTPM]":"62.4","Cell RNA - JURKAT [nTPM]":"31.1","Cell RNA - K-562 [nTPM]":"23.4","Cell RNA - Karpas-707 [nTPM]":"39.4","Cell RNA - LHCN-M2 [nTPM]":"87.7","Cell RNA - MCF7 [nTPM]":"75.8","Cell RNA - MOLT-4 [nTPM]":"22.9","Cell RNA - NB-4 [nTPM]":"32.4","Cell RNA - NTERA-2 [nTPM]":"23.0","Cell RNA - OE19 [nTPM]":"20.5","Cell RNA - PC-3 [nTPM]":"39.1","Cell RNA - REH [nTPM]":"45.8","Cell RNA - RH-30 [nTPM]":"39.6","Cell RNA - RPMI-8226 [nTPM]":"78.8","Cell RNA - RPTEC TERT1 [nTPM]":"44.3","Cell RNA - RT4 [nTPM]":"30.1","Cell RNA - SCLC-21H [nTPM]":"42.1","Cell RNA - SH-SY5Y [nTPM]":"38.7","Cell RNA - SiHa [nTPM]":"31.3","Cell RNA - SK-BR-3 [nTPM]":"72.4","Cell RNA - SK-MEL-30 [nTPM]":"24.6","Cell RNA - SuSa [nTPM]":"22.9","Cell RNA - T-47d [nTPM]":"44.5","Cell RNA - THP-1 [nTPM]":"24.6","Cell RNA - TIME [nTPM]":"41.1","Cell RNA - U-138 MG [nTPM]":"44.2","Cell RNA - U-2 OS [nTPM]":"26.1","Cell RNA - U-2197 [nTPM]":"45.8","Cell RNA - U-251 MG [nTPM]":"32.2","Cell RNA - U-266\/70 [nTPM]":"44.5","Cell RNA - U-266\/84 [nTPM]":"15.7","Cell RNA - U-698 [nTPM]":"15.1","Cell RNA - U-87 MG [nTPM]":"50.3","Cell RNA - U-937 [nTPM]":"33.7","Cell RNA - WM-115 [nTPM]":"42.6","Blood RNA - basophil [nTPM]":"58.1","Blood RNA - classical monocyte [nTPM]":"115.0","Blood RNA - eosinophil [nTPM]":"85.2","Blood RNA - gdT-cell [nTPM]":"17.7","Blood RNA - intermediate monocyte [nTPM]":"97.6","Blood RNA - MAIT T-cell [nTPM]":"17.2","Blood RNA - memory B-cell [nTPM]":"22.8","Blood RNA - memory CD4 T-cell [nTPM]":"16.5","Blood RNA - memory CD8 T-cell [nTPM]":"13.9","Blood RNA - myeloid DC [nTPM]":"95.9","Blood RNA - naive B-cell [nTPM]":"19.0","Blood RNA - naive CD4 T-cell [nTPM]":"13.6","Blood RNA - naive CD8 T-cell [nTPM]":"16.1","Blood RNA - neutrophil [nTPM]":"89.7","Blood RNA - NK-cell [nTPM]":"22.8","Blood RNA - non-classical monocyte [nTPM]":"71.2","Blood RNA - plasmacytoid DC [nTPM]":"19.3","Blood RNA - T-reg [nTPM]":"24.5","Blood RNA - total PBMC [nTPM]":"53.1","Brain RNA - amygdala [nTPM]":"18.4","Brain RNA - basal ganglia [nTPM]":"18.6","Brain RNA - cerebellum [nTPM]":"17.4","Brain RNA - cerebral cortex [nTPM]":"23.8","Brain RNA - hippocampal formation [nTPM]":"18.8","Brain RNA - hypothalamus [nTPM]":"17.8","Brain RNA - medulla oblongata [nTPM]":"20.6","Brain RNA - midbrain [nTPM]":"20.7","Brain RNA - pons [nTPM]":"19.3","Brain RNA - spinal cord [nTPM]":"17.1","Brain RNA - thalamus [nTPM]":"18.5","Brain RNA - white matter [nTPM]":"17.5","Single Cell Type RNA - Adipocytes [nTPM]":"27.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.1","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"20.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"61.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.2","Single Cell Type RNA - Bipolar cells [nTPM]":"11.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"30.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"27.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"39.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"28.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"55.4","Single Cell Type RNA - dendritic cells [nTPM]":"9.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"31.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"80.3","Single Cell Type RNA - Ductal cells [nTPM]":"68.6","Single Cell Type RNA - Early spermatids [nTPM]":"2.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"24.3","Single Cell Type RNA - Endothelial cells [nTPM]":"29.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.9","Single Cell Type RNA - Erythroid cells [nTPM]":"16.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"78.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"71.1","Single Cell Type RNA - Fibroblasts [nTPM]":"24.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"25.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.0","Single Cell Type RNA - granulocytes [nTPM]":"33.0","Single Cell Type RNA - Granulosa cells [nTPM]":"35.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.4","Single Cell Type RNA - Hepatocytes [nTPM]":"43.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"93.0","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"22.3","Single Cell Type RNA - Ionocytes [nTPM]":"42.7","Single Cell Type RNA - Kupffer cells [nTPM]":"44.5","Single Cell Type RNA - Langerhans cells [nTPM]":"50.3","Single Cell Type RNA - Late spermatids [nTPM]":"7.8","Single Cell Type RNA - Leydig cells [nTPM]":"20.8","Single Cell Type RNA - Macrophages [nTPM]":"53.1","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"79.3","Single Cell Type RNA - Muller glia cells [nTPM]":"22.6","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"54.8","Single Cell Type RNA - Paneth cells [nTPM]":"48.4","Single Cell Type RNA - Peritubular cells [nTPM]":"25.6","Single Cell Type RNA - Plasma cells [nTPM]":"51.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"66.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"95.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.8","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"33.2","Single Cell Type RNA - Spermatocytes [nTPM]":"25.8","Single Cell Type RNA - Spermatogonia [nTPM]":"14.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"69.4","Single Cell Type RNA - T-cells [nTPM]":"12.1","Single Cell Type RNA - Theca cells [nTPM]":"45.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.0","Single Cell Type RNA - Urothelial cells [nTPM]":"27.0"},{"Gene":"BCO1","Gene synonym":["BCDO","BCDO1","BCMO","BCMO1","FLJ10730"],"Ensembl":"ENSG00000135697","Gene description":"Beta-carotene oxygenase 1","Uniprot":["Q9HAY6"],"Chromosome":"16","Position":"81238689-81291142","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Dioxygenase","Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"5.0","intestine":"14.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"6.2","Distal enterocytes":"4.8","Excitatory neurons":"8.0","Intestinal goblet cells":"5.5","Proximal enterocytes":"13.6","Proximal tubular cells":"8.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"3.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"11.5","EFO-21":"8.7","HAP1":"3.3","NTERA-2":"4.6","RPTEC TERT1":"8.6"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043811"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Actin filaments","Centriolar satellite"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Actin filaments","Centriolar satellite"],"Subcellular additional location":null,"Antibody RRID":{"HPA043811":"AB_10962487"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"1.8","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"1.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"1.2","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"5.0","Tissue RNA - colon [nTPM]":"2.6","Tissue RNA - duodenum [nTPM]":"9.3","Tissue RNA - endometrium 1 [nTPM]":"0.6","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"1.2","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"2.5","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"3.5","Tissue RNA - liver [nTPM]":"0.8","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"0.9","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.7","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"3.0","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"1.5","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"14.6","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"1.9","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.7","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"11.5","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"2.3","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"8.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"3.3","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.5","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"4.6","Cell RNA - OE19 [nTPM]":"0.8","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"8.6","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.8","Brain RNA - basal ganglia [nTPM]":"1.3","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"1.2","Brain RNA - hippocampal formation [nTPM]":"2.5","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.7","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"6.2","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"2.1","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"BCS1L","Gene synonym":["BCS","BJS","h-BCS","Hs.6719"],"Ensembl":"ENSG00000074582","Gene description":"BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone","Uniprot":["Q9Y276"],"Chromosome":"2","Position":"218658764-218663443","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":["Deafness","Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037700","HPA037701"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA037700":"AB_10794619","HPA037701":"AB_10805235"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.31e-4"},"Tissue RNA - adipose tissue [nTPM]":"19.9","Tissue RNA - adrenal gland [nTPM]":"29.3","Tissue RNA - amygdala [nTPM]":"24.0","Tissue RNA - appendix [nTPM]":"11.5","Tissue RNA - basal ganglia [nTPM]":"24.8","Tissue RNA - bone marrow [nTPM]":"12.4","Tissue RNA - breast [nTPM]":"21.3","Tissue RNA - cerebellum [nTPM]":"25.0","Tissue RNA - cerebral cortex [nTPM]":"25.9","Tissue RNA - cervix [nTPM]":"24.9","Tissue RNA - choroid plexus [nTPM]":"23.9","Tissue RNA - colon [nTPM]":"22.6","Tissue RNA - duodenum [nTPM]":"15.9","Tissue RNA - endometrium 1 [nTPM]":"21.6","Tissue RNA - epididymis [nTPM]":"14.3","Tissue RNA - esophagus [nTPM]":"28.2","Tissue RNA - fallopian tube [nTPM]":"20.3","Tissue RNA - gallbladder [nTPM]":"10.9","Tissue RNA - heart muscle [nTPM]":"40.8","Tissue RNA - hippocampal formation [nTPM]":"24.3","Tissue RNA - hypothalamus [nTPM]":"25.0","Tissue RNA - kidney [nTPM]":"30.5","Tissue RNA - liver [nTPM]":"39.9","Tissue RNA - lung [nTPM]":"16.3","Tissue RNA - lymph node [nTPM]":"15.5","Tissue RNA - medulla oblongata [nTPM]":"25.2","Tissue RNA - midbrain [nTPM]":"25.4","Tissue RNA - ovary [nTPM]":"25.2","Tissue RNA - pancreas [nTPM]":"41.2","Tissue RNA - parathyroid gland [nTPM]":"17.8","Tissue RNA - pituitary gland [nTPM]":"17.4","Tissue RNA - placenta [nTPM]":"11.8","Tissue RNA - pons [nTPM]":"26.1","Tissue RNA - prostate [nTPM]":"27.2","Tissue RNA - rectum [nTPM]":"16.5","Tissue RNA - retina [nTPM]":"13.5","Tissue RNA - salivary gland [nTPM]":"20.8","Tissue RNA - seminal vesicle [nTPM]":"17.4","Tissue RNA - skeletal muscle [nTPM]":"32.0","Tissue RNA - skin 1 [nTPM]":"24.2","Tissue RNA - small intestine [nTPM]":"20.9","Tissue RNA - smooth muscle [nTPM]":"16.8","Tissue RNA - spinal cord [nTPM]":"24.5","Tissue RNA - spleen [nTPM]":"24.2","Tissue RNA - stomach 1 [nTPM]":"25.8","Tissue RNA - testis [nTPM]":"10.1","Tissue RNA - thalamus [nTPM]":"24.8","Tissue RNA - thymus [nTPM]":"9.8","Tissue RNA - thyroid gland [nTPM]":"22.1","Tissue RNA - tongue [nTPM]":"22.5","Tissue RNA - tonsil [nTPM]":"14.4","Tissue RNA - urinary bladder [nTPM]":"25.5","Tissue RNA - vagina [nTPM]":"23.5","Tissue RNA - white matter [nTPM]":"26.1","Cell RNA - A-431 [nTPM]":"17.1","Cell RNA - A549 [nTPM]":"34.3","Cell RNA - AF22 [nTPM]":"19.3","Cell RNA - AN3-CA [nTPM]":"26.8","Cell RNA - ASC diff [nTPM]":"42.8","Cell RNA - ASC TERT1 [nTPM]":"28.6","Cell RNA - BEWO [nTPM]":"28.9","Cell RNA - BJ [nTPM]":"28.4","Cell RNA - BJ hTERT+ [nTPM]":"15.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"44.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"32.9","Cell RNA - CACO-2 [nTPM]":"92.1","Cell RNA - CAPAN-2 [nTPM]":"28.0","Cell RNA - Daudi [nTPM]":"25.2","Cell RNA - EFO-21 [nTPM]":"40.4","Cell RNA - fHDF\/TERT166 [nTPM]":"29.1","Cell RNA - GAMG [nTPM]":"30.3","Cell RNA - HaCaT [nTPM]":"46.2","Cell RNA - HAP1 [nTPM]":"63.0","Cell RNA - HBEC3-KT [nTPM]":"73.1","Cell RNA - HBF TERT88 [nTPM]":"25.4","Cell RNA - HDLM-2 [nTPM]":"37.2","Cell RNA - HEK 293 [nTPM]":"67.9","Cell RNA - HEL [nTPM]":"40.4","Cell RNA - HeLa [nTPM]":"45.5","Cell RNA - Hep G2 [nTPM]":"76.0","Cell RNA - HHSteC [nTPM]":"49.4","Cell RNA - HL-60 [nTPM]":"35.6","Cell RNA - HMC-1 [nTPM]":"24.4","Cell RNA - HSkMC [nTPM]":"36.6","Cell RNA - hTCEpi [nTPM]":"55.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"61.1","Cell RNA - hTERT-HME1 [nTPM]":"79.5","Cell RNA - hTERT-RPE1 [nTPM]":"18.4","Cell RNA - HUVEC TERT2 [nTPM]":"46.0","Cell RNA - JURKAT [nTPM]":"35.3","Cell RNA - K-562 [nTPM]":"58.3","Cell RNA - Karpas-707 [nTPM]":"35.6","Cell RNA - LHCN-M2 [nTPM]":"41.1","Cell RNA - MCF7 [nTPM]":"57.7","Cell RNA - MOLT-4 [nTPM]":"26.6","Cell RNA - NB-4 [nTPM]":"48.2","Cell RNA - NTERA-2 [nTPM]":"23.7","Cell RNA - OE19 [nTPM]":"39.9","Cell RNA - PC-3 [nTPM]":"43.5","Cell RNA - REH [nTPM]":"38.3","Cell RNA - RH-30 [nTPM]":"23.8","Cell RNA - RPMI-8226 [nTPM]":"40.0","Cell RNA - RPTEC TERT1 [nTPM]":"37.6","Cell RNA - RT4 [nTPM]":"31.1","Cell RNA - SCLC-21H [nTPM]":"41.1","Cell RNA - SH-SY5Y [nTPM]":"17.9","Cell RNA - SiHa [nTPM]":"20.1","Cell RNA - SK-BR-3 [nTPM]":"48.2","Cell RNA - SK-MEL-30 [nTPM]":"36.9","Cell RNA - SuSa [nTPM]":"30.4","Cell RNA - T-47d [nTPM]":"25.4","Cell RNA - THP-1 [nTPM]":"34.9","Cell RNA - TIME [nTPM]":"26.7","Cell RNA - U-138 MG [nTPM]":"33.3","Cell RNA - U-2 OS [nTPM]":"27.7","Cell RNA - U-2197 [nTPM]":"22.3","Cell RNA - U-251 MG [nTPM]":"39.5","Cell RNA - U-266\/70 [nTPM]":"28.1","Cell RNA - U-266\/84 [nTPM]":"23.2","Cell RNA - U-698 [nTPM]":"43.2","Cell RNA - U-87 MG [nTPM]":"21.1","Cell RNA - U-937 [nTPM]":"54.2","Cell RNA - WM-115 [nTPM]":"32.6","Blood RNA - basophil [nTPM]":"20.1","Blood RNA - classical monocyte [nTPM]":"12.2","Blood RNA - eosinophil [nTPM]":"10.5","Blood RNA - gdT-cell [nTPM]":"10.3","Blood RNA - intermediate monocyte [nTPM]":"7.7","Blood RNA - MAIT T-cell [nTPM]":"11.7","Blood RNA - memory B-cell [nTPM]":"13.5","Blood RNA - memory CD4 T-cell [nTPM]":"8.1","Blood RNA - memory CD8 T-cell [nTPM]":"9.7","Blood RNA - myeloid DC [nTPM]":"24.6","Blood RNA - naive B-cell [nTPM]":"12.8","Blood RNA - naive CD4 T-cell [nTPM]":"9.9","Blood RNA - naive CD8 T-cell [nTPM]":"11.9","Blood RNA - neutrophil [nTPM]":"1.4","Blood RNA - NK-cell [nTPM]":"7.7","Blood RNA - non-classical monocyte [nTPM]":"1.1","Blood RNA - plasmacytoid DC [nTPM]":"13.7","Blood RNA - T-reg [nTPM]":"13.4","Blood RNA - total PBMC [nTPM]":"10.2","Brain RNA - amygdala [nTPM]":"24.0","Brain RNA - basal ganglia [nTPM]":"24.8","Brain RNA - cerebellum [nTPM]":"25.0","Brain RNA - cerebral cortex [nTPM]":"25.9","Brain RNA - hippocampal formation [nTPM]":"24.3","Brain RNA - hypothalamus [nTPM]":"25.0","Brain RNA - medulla oblongata [nTPM]":"25.2","Brain RNA - midbrain [nTPM]":"25.4","Brain RNA - pons [nTPM]":"26.1","Brain RNA - spinal cord [nTPM]":"24.5","Brain RNA - thalamus [nTPM]":"24.8","Brain RNA - white matter [nTPM]":"26.1","Single Cell Type RNA - Adipocytes [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.5","Single Cell Type RNA - Astrocytes [nTPM]":"6.5","Single Cell Type RNA - B-cells [nTPM]":"6.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"13.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"32.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"18.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"31.4","Single Cell Type RNA - dendritic cells [nTPM]":"5.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"18.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.4","Single Cell Type RNA - Endothelial cells [nTPM]":"13.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.1","Single Cell Type RNA - Erythroid cells [nTPM]":"7.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.0","Single Cell Type RNA - Fibroblasts [nTPM]":"13.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.8","Single Cell Type RNA - granulocytes [nTPM]":"11.4","Single Cell Type RNA - Granulosa cells [nTPM]":"14.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.4","Single Cell Type RNA - Hepatocytes [nTPM]":"11.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.4","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.0","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"5.0","Single Cell Type RNA - Langerhans cells [nTPM]":"9.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"9.0","Single Cell Type RNA - Macrophages [nTPM]":"6.6","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"9.2","Single Cell Type RNA - Muller glia cells [nTPM]":"12.1","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.4","Single Cell Type RNA - Paneth cells [nTPM]":"12.7","Single Cell Type RNA - Peritubular cells [nTPM]":"15.4","Single Cell Type RNA - Plasma cells [nTPM]":"9.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.4","Single Cell Type RNA - Spermatocytes [nTPM]":"5.5","Single Cell Type RNA - Spermatogonia [nTPM]":"11.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.5","Single Cell Type RNA - T-cells [nTPM]":"6.4","Single Cell Type RNA - Theca cells [nTPM]":"18.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.0","Single Cell Type RNA - Urothelial cells [nTPM]":"12.9"},{"Gene":"BEST1","Gene synonym":["BEST","BMD","RP50","VMD2"],"Ensembl":"ENSG00000167995","Gene description":"Bestrophin 1","Uniprot":["O76090"],"Chromosome":"11","Position":"61950063-61965515","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sensory transduction","Transport","Vision"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"26.3","brain":"41.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"272.8"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"2.0","melanoma":"6.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"neutrophil":"37.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"37.6"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"SK-MEL-30":"71.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057464"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 11: Alveolar cells - Smell perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA057464":"AB_2683444"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-3"},"Tissue RNA - adipose tissue [nTPM]":"9.1","Tissue RNA - adrenal gland [nTPM]":"3.7","Tissue RNA - amygdala [nTPM]":"16.3","Tissue RNA - appendix [nTPM]":"8.3","Tissue RNA - basal ganglia [nTPM]":"30.5","Tissue RNA - bone marrow [nTPM]":"26.3","Tissue RNA - breast [nTPM]":"5.3","Tissue RNA - cerebellum [nTPM]":"24.9","Tissue RNA - cerebral cortex [nTPM]":"23.2","Tissue RNA - cervix [nTPM]":"5.3","Tissue RNA - choroid plexus [nTPM]":"10.2","Tissue RNA - colon [nTPM]":"3.8","Tissue RNA - duodenum [nTPM]":"1.7","Tissue RNA - endometrium 1 [nTPM]":"4.1","Tissue RNA - epididymis [nTPM]":"10.0","Tissue RNA - esophagus [nTPM]":"2.8","Tissue RNA - fallopian tube [nTPM]":"5.9","Tissue RNA - gallbladder [nTPM]":"5.1","Tissue RNA - heart muscle [nTPM]":"5.7","Tissue RNA - hippocampal formation [nTPM]":"16.5","Tissue RNA - hypothalamus [nTPM]":"20.2","Tissue RNA - kidney [nTPM]":"3.7","Tissue RNA - liver [nTPM]":"2.6","Tissue RNA - lung [nTPM]":"10.3","Tissue RNA - lymph node [nTPM]":"2.3","Tissue RNA - medulla oblongata [nTPM]":"27.9","Tissue RNA - midbrain [nTPM]":"27.3","Tissue RNA - ovary [nTPM]":"4.6","Tissue RNA - pancreas [nTPM]":"2.5","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"3.4","Tissue RNA - placenta [nTPM]":"2.4","Tissue RNA - pons [nTPM]":"26.7","Tissue RNA - prostate [nTPM]":"4.0","Tissue RNA - rectum [nTPM]":"1.0","Tissue RNA - retina [nTPM]":"6.7","Tissue RNA - salivary gland [nTPM]":"2.2","Tissue RNA - seminal vesicle [nTPM]":"2.0","Tissue RNA - skeletal muscle [nTPM]":"1.6","Tissue RNA - skin 1 [nTPM]":"2.7","Tissue RNA - small intestine [nTPM]":"3.9","Tissue RNA - smooth muscle [nTPM]":"1.8","Tissue RNA - spinal cord [nTPM]":"19.2","Tissue RNA - spleen [nTPM]":"11.0","Tissue RNA - stomach 1 [nTPM]":"3.3","Tissue RNA - testis [nTPM]":"5.4","Tissue RNA - thalamus [nTPM]":"28.6","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"2.7","Tissue RNA - tongue [nTPM]":"1.4","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"5.3","Tissue RNA - vagina [nTPM]":"4.7","Tissue RNA - white matter [nTPM]":"41.7","Cell RNA - A-431 [nTPM]":"0.8","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"0.7","Cell RNA - ASC diff [nTPM]":"17.7","Cell RNA - ASC TERT1 [nTPM]":"3.8","Cell RNA - BEWO [nTPM]":"1.4","Cell RNA - BJ [nTPM]":"1.0","Cell RNA - BJ hTERT+ [nTPM]":"1.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.3","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"0.5","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"1.7","Cell RNA - fHDF\/TERT166 [nTPM]":"1.1","Cell RNA - GAMG [nTPM]":"2.0","Cell RNA - HaCaT [nTPM]":"1.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"6.7","Cell RNA - Hep G2 [nTPM]":"0.9","Cell RNA - HHSteC [nTPM]":"4.9","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"5.6","Cell RNA - hTCEpi [nTPM]":"1.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.9","Cell RNA - hTERT-HME1 [nTPM]":"4.1","Cell RNA - hTERT-RPE1 [nTPM]":"1.8","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.8","Cell RNA - K-562 [nTPM]":"0.8","Cell RNA - Karpas-707 [nTPM]":"7.6","Cell RNA - LHCN-M2 [nTPM]":"1.9","Cell RNA - MCF7 [nTPM]":"0.6","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.8","Cell RNA - PC-3 [nTPM]":"2.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"2.0","Cell RNA - SCLC-21H [nTPM]":"1.0","Cell RNA - SH-SY5Y [nTPM]":"0.9","Cell RNA - SiHa [nTPM]":"1.6","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"71.6","Cell RNA - SuSa [nTPM]":"0.8","Cell RNA - T-47d [nTPM]":"0.7","Cell RNA - THP-1 [nTPM]":"2.3","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.9","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.7","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"10.3","Cell RNA - U-266\/84 [nTPM]":"0.8","Cell RNA - U-698 [nTPM]":"0.7","Cell RNA - U-87 MG [nTPM]":"4.8","Cell RNA - U-937 [nTPM]":"0.6","Cell RNA - WM-115 [nTPM]":"1.2","Blood RNA - basophil [nTPM]":"2.6","Blood RNA - classical monocyte [nTPM]":"3.9","Blood RNA - eosinophil [nTPM]":"3.9","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"4.6","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"2.6","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"37.6","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"5.1","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"1.9","Brain RNA - amygdala [nTPM]":"16.3","Brain RNA - basal ganglia [nTPM]":"30.5","Brain RNA - cerebellum [nTPM]":"24.9","Brain RNA - cerebral cortex [nTPM]":"23.2","Brain RNA - hippocampal formation [nTPM]":"16.5","Brain RNA - hypothalamus [nTPM]":"20.2","Brain RNA - medulla oblongata [nTPM]":"27.9","Brain RNA - midbrain [nTPM]":"27.3","Brain RNA - pons [nTPM]":"26.7","Brain RNA - spinal cord [nTPM]":"19.2","Brain RNA - thalamus [nTPM]":"28.6","Brain RNA - white matter [nTPM]":"41.7","Single Cell Type RNA - Adipocytes [nTPM]":"2.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"59.3","Single Cell Type RNA - Astrocytes [nTPM]":"9.1","Single Cell Type RNA - B-cells [nTPM]":"11.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"36.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"54.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Bipolar cells [nTPM]":"2.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"57.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.5","Single Cell Type RNA - dendritic cells [nTPM]":"5.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"22.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.8","Single Cell Type RNA - Early spermatids [nTPM]":"8.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.0","Single Cell Type RNA - Endothelial cells [nTPM]":"16.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.3","Single Cell Type RNA - Erythroid cells [nTPM]":"29.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"23.4","Single Cell Type RNA - Fibroblasts [nTPM]":"32.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.0","Single Cell Type RNA - granulocytes [nTPM]":"76.4","Single Cell Type RNA - Granulosa cells [nTPM]":"1.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.0","Single Cell Type RNA - Hepatocytes [nTPM]":"13.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"37.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.7","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"75.4","Single Cell Type RNA - Langerhans cells [nTPM]":"272.8","Single Cell Type RNA - Late spermatids [nTPM]":"2.9","Single Cell Type RNA - Leydig cells [nTPM]":"15.2","Single Cell Type RNA - Macrophages [nTPM]":"49.0","Single Cell Type RNA - Melanocytes [nTPM]":"55.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"14.1","Single Cell Type RNA - Muller glia cells [nTPM]":"6.0","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"43.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.1","Single Cell Type RNA - Paneth cells [nTPM]":"21.0","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"5.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"28.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"37.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.8","Single Cell Type RNA - Spermatocytes [nTPM]":"3.2","Single Cell Type RNA - Spermatogonia [nTPM]":"4.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"32.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.4","Single Cell Type RNA - T-cells [nTPM]":"24.5","Single Cell Type RNA - Theca cells [nTPM]":"0.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.9","Single Cell Type RNA - Urothelial cells [nTPM]":"13.2"},{"Gene":"BIRC3","Gene synonym":["API2","c-IAP2","cIAP2","hiap-1","MALT2","MIHC","RNF49"],"Ensembl":"ENSG00000023445","Gene description":"Baculoviral IAP repeat containing 3","Uniprot":["Q13489"],"Chromosome":"11","Position":"102317450-102339403","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"89.0","lymphoid tissue":"141.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"554.8","Langerhans cells":"1400.9","monocytes":"1117.0","Proximal enterocytes":"817.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"209.0","naive B-cell":"159.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"B-cells":"209.0","T-cells":"83.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"146.5","Daudi":"140.7","EFO-21":"74.3","HDLM-2":"140.1","hTERT-HME1":"140.2","U-266\/70":"89.2","U-266\/84":"85.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002317"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 3: Monocytes - Immune response regulation","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA002317":"AB_1846748"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.60e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.35e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.28e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.03e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.66e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.0","Tissue RNA - adrenal gland [nTPM]":"14.7","Tissue RNA - amygdala [nTPM]":"2.7","Tissue RNA - appendix [nTPM]":"104.8","Tissue RNA - basal ganglia [nTPM]":"2.9","Tissue RNA - bone marrow [nTPM]":"26.3","Tissue RNA - breast [nTPM]":"18.4","Tissue RNA - cerebellum [nTPM]":"1.6","Tissue RNA - cerebral cortex [nTPM]":"3.4","Tissue RNA - cervix [nTPM]":"19.1","Tissue RNA - choroid plexus [nTPM]":"3.4","Tissue RNA - colon [nTPM]":"24.9","Tissue RNA - duodenum [nTPM]":"26.6","Tissue RNA - endometrium 1 [nTPM]":"10.5","Tissue RNA - epididymis [nTPM]":"3.7","Tissue RNA - esophagus [nTPM]":"16.0","Tissue RNA - fallopian tube [nTPM]":"8.5","Tissue RNA - gallbladder [nTPM]":"51.0","Tissue RNA - heart muscle [nTPM]":"7.7","Tissue RNA - hippocampal formation [nTPM]":"2.8","Tissue RNA - hypothalamus [nTPM]":"3.5","Tissue RNA - kidney [nTPM]":"12.6","Tissue RNA - liver [nTPM]":"26.3","Tissue RNA - lung [nTPM]":"24.6","Tissue RNA - lymph node [nTPM]":"141.5","Tissue RNA - medulla oblongata [nTPM]":"2.6","Tissue RNA - midbrain [nTPM]":"2.7","Tissue RNA - ovary [nTPM]":"6.6","Tissue RNA - pancreas [nTPM]":"12.0","Tissue RNA - parathyroid gland [nTPM]":"4.3","Tissue RNA - pituitary gland [nTPM]":"3.6","Tissue RNA - placenta [nTPM]":"5.3","Tissue RNA - pons [nTPM]":"2.3","Tissue RNA - prostate [nTPM]":"10.6","Tissue RNA - rectum [nTPM]":"24.7","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"12.7","Tissue RNA - seminal vesicle [nTPM]":"11.4","Tissue RNA - skeletal muscle [nTPM]":"2.7","Tissue RNA - skin 1 [nTPM]":"8.1","Tissue RNA - small intestine [nTPM]":"89.0","Tissue RNA - smooth muscle [nTPM]":"10.7","Tissue RNA - spinal cord [nTPM]":"2.5","Tissue RNA - spleen [nTPM]":"73.2","Tissue RNA - stomach 1 [nTPM]":"54.3","Tissue RNA - testis [nTPM]":"8.2","Tissue RNA - thalamus [nTPM]":"2.7","Tissue RNA - thymus [nTPM]":"59.2","Tissue RNA - thyroid gland [nTPM]":"3.9","Tissue RNA - tongue [nTPM]":"4.3","Tissue RNA - tonsil [nTPM]":"134.4","Tissue RNA - urinary bladder [nTPM]":"46.9","Tissue RNA - vagina [nTPM]":"4.8","Tissue RNA - white matter [nTPM]":"3.6","Cell RNA - A-431 [nTPM]":"26.4","Cell RNA - A549 [nTPM]":"24.5","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"0.7","Cell RNA - ASC TERT1 [nTPM]":"3.9","Cell RNA - BEWO [nTPM]":"2.4","Cell RNA - BJ [nTPM]":"2.5","Cell RNA - BJ hTERT+ [nTPM]":"17.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.7","Cell RNA - CACO-2 [nTPM]":"4.6","Cell RNA - CAPAN-2 [nTPM]":"146.5","Cell RNA - Daudi [nTPM]":"140.7","Cell RNA - EFO-21 [nTPM]":"74.3","Cell RNA - fHDF\/TERT166 [nTPM]":"1.4","Cell RNA - GAMG [nTPM]":"22.8","Cell RNA - HaCaT [nTPM]":"13.0","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"4.6","Cell RNA - HBF TERT88 [nTPM]":"7.8","Cell RNA - HDLM-2 [nTPM]":"140.1","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.5","Cell RNA - HeLa [nTPM]":"7.3","Cell RNA - Hep G2 [nTPM]":"1.4","Cell RNA - HHSteC [nTPM]":"30.7","Cell RNA - HL-60 [nTPM]":"2.4","Cell RNA - HMC-1 [nTPM]":"3.7","Cell RNA - HSkMC [nTPM]":"3.5","Cell RNA - hTCEpi [nTPM]":"18.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.4","Cell RNA - hTERT-HME1 [nTPM]":"140.2","Cell RNA - hTERT-RPE1 [nTPM]":"4.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.4","Cell RNA - JURKAT [nTPM]":"10.2","Cell RNA - K-562 [nTPM]":"0.5","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"3.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"8.3","Cell RNA - NB-4 [nTPM]":"1.3","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"14.2","Cell RNA - PC-3 [nTPM]":"1.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.8","Cell RNA - RPMI-8226 [nTPM]":"6.8","Cell RNA - RPTEC TERT1 [nTPM]":"34.3","Cell RNA - RT4 [nTPM]":"12.9","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"2.1","Cell RNA - SK-BR-3 [nTPM]":"2.1","Cell RNA - SK-MEL-30 [nTPM]":"1.8","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"6.4","Cell RNA - THP-1 [nTPM]":"1.8","Cell RNA - TIME [nTPM]":"7.5","Cell RNA - U-138 MG [nTPM]":"25.6","Cell RNA - U-2 OS [nTPM]":"3.4","Cell RNA - U-2197 [nTPM]":"1.4","Cell RNA - U-251 MG [nTPM]":"28.3","Cell RNA - U-266\/70 [nTPM]":"89.2","Cell RNA - U-266\/84 [nTPM]":"85.8","Cell RNA - U-698 [nTPM]":"48.8","Cell RNA - U-87 MG [nTPM]":"4.0","Cell RNA - U-937 [nTPM]":"7.4","Cell RNA - WM-115 [nTPM]":"3.0","Blood RNA - basophil [nTPM]":"8.6","Blood RNA - classical monocyte [nTPM]":"3.9","Blood RNA - eosinophil [nTPM]":"2.2","Blood RNA - gdT-cell [nTPM]":"5.8","Blood RNA - intermediate monocyte [nTPM]":"10.1","Blood RNA - MAIT T-cell [nTPM]":"9.8","Blood RNA - memory B-cell [nTPM]":"209.0","Blood RNA - memory CD4 T-cell [nTPM]":"41.7","Blood RNA - memory CD8 T-cell [nTPM]":"14.1","Blood RNA - myeloid DC [nTPM]":"3.6","Blood RNA - naive B-cell [nTPM]":"159.9","Blood RNA - naive CD4 T-cell [nTPM]":"28.4","Blood RNA - naive CD8 T-cell [nTPM]":"8.3","Blood RNA - neutrophil [nTPM]":"2.6","Blood RNA - NK-cell [nTPM]":"9.9","Blood RNA - non-classical monocyte [nTPM]":"11.0","Blood RNA - plasmacytoid DC [nTPM]":"1.7","Blood RNA - T-reg [nTPM]":"83.6","Blood RNA - total PBMC [nTPM]":"11.9","Brain RNA - amygdala [nTPM]":"2.7","Brain RNA - basal ganglia [nTPM]":"2.9","Brain RNA - cerebellum [nTPM]":"1.6","Brain RNA - cerebral cortex [nTPM]":"3.4","Brain RNA - hippocampal formation [nTPM]":"2.8","Brain RNA - hypothalamus [nTPM]":"3.5","Brain RNA - medulla oblongata [nTPM]":"2.6","Brain RNA - midbrain [nTPM]":"2.7","Brain RNA - pons [nTPM]":"2.3","Brain RNA - spinal cord [nTPM]":"2.5","Brain RNA - thalamus [nTPM]":"2.7","Brain RNA - white matter [nTPM]":"3.6","Single Cell Type RNA - Adipocytes [nTPM]":"41.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"144.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"70.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"420.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"101.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"324.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"267.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"51.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"22.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"134.4","Single Cell Type RNA - Club cells [nTPM]":"146.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.0","Single Cell Type RNA - dendritic cells [nTPM]":"71.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"142.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"230.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"231.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.8","Single Cell Type RNA - Endothelial cells [nTPM]":"101.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.0","Single Cell Type RNA - Erythroid cells [nTPM]":"23.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"179.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"63.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"184.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"289.4","Single Cell Type RNA - granulocytes [nTPM]":"554.8","Single Cell Type RNA - Granulosa cells [nTPM]":"1.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"4.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"38.0","Single Cell Type RNA - Ionocytes [nTPM]":"75.3","Single Cell Type RNA - Kupffer cells [nTPM]":"25.4","Single Cell Type RNA - Langerhans cells [nTPM]":"1400.9","Single Cell Type RNA - Late spermatids [nTPM]":"2.1","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"170.0","Single Cell Type RNA - Melanocytes [nTPM]":"192.1","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"1117.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"207.4","Single Cell Type RNA - Paneth cells [nTPM]":"281.1","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"288.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"455.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"817.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"88.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"60.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"90.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"31.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"84.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"278.0","Single Cell Type RNA - Theca cells [nTPM]":"0.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"49.4","Single Cell Type RNA - Urothelial cells [nTPM]":"193.3"},{"Gene":"BLK","Gene synonym":["MGC10442"],"Ensembl":"ENSG00000136573","Gene description":"BLK proto-oncogene, Src family tyrosine kinase","Uniprot":["P51451"],"Chromosome":"8","Position":"11486894-11564599","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"16","RNA tissue specific nTPM":{"intestine":"39.1","lymphoid tissue":"46.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"B-cells":"116.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"memory B-cell":"183.4","naive B-cell":"131.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"183.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"106.6","REH":"29.9","RPMI-8226":"38.5","U-698":"48.6","U-87 MG":"22.7"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005093","HPA069571"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB005093":"AB_2274756","HPA069571":"AB_2732137"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.94e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"9.1","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"2.6","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"2.6","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"1.2","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"1.2","Tissue RNA - liver [nTPM]":"0.7","Tissue RNA - lung [nTPM]":"0.8","Tissue RNA - lymph node [nTPM]":"29.9","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.7","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"39.1","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"46.7","Tissue RNA - stomach 1 [nTPM]":"2.1","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"2.5","Tissue RNA - thyroid gland [nTPM]":"1.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"27.9","Tissue RNA - urinary bladder [nTPM]":"1.4","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"106.6","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"4.1","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"29.9","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"38.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.6","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"5.4","Cell RNA - U-266\/84 [nTPM]":"10.2","Cell RNA - U-698 [nTPM]":"48.6","Cell RNA - U-87 MG [nTPM]":"22.7","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"2.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"37.9","Blood RNA - memory B-cell [nTPM]":"183.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.4","Blood RNA - memory CD8 T-cell [nTPM]":"4.6","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"131.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.9","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"17.5","Blood RNA - T-reg [nTPM]":"1.8","Blood RNA - total PBMC [nTPM]":"9.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"116.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"4.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"3.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"1.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"10.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"4.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"BLM","Gene synonym":["BS","RECQ2","RECQL3"],"Ensembl":"ENSG00000197299","Gene description":"BLM RecQ like helicase","Uniprot":["P54132"],"Chromosome":"15","Position":"90717346-90816166","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","DNA replication"],"Molecular function":["DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"5.7","lymphoid tissue":"7.9","salivary gland":"7.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"18.3","Oligodendrocyte precursor cells":"58.3","Plasma cells":"20.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005689"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA005689":"AB_1845372"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-15"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.9","Tissue RNA - appendix [nTPM]":"3.6","Tissue RNA - basal ganglia [nTPM]":"1.1","Tissue RNA - bone marrow [nTPM]":"5.7","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"2.3","Tissue RNA - cerebral cortex [nTPM]":"0.9","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"1.4","Tissue RNA - duodenum [nTPM]":"1.0","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"0.6","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"0.8","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"6.4","Tissue RNA - medulla oblongata [nTPM]":"1.2","Tissue RNA - midbrain [nTPM]":"1.4","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.6","Tissue RNA - placenta [nTPM]":"1.2","Tissue RNA - pons [nTPM]":"1.1","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"1.7","Tissue RNA - retina [nTPM]":"2.4","Tissue RNA - salivary gland [nTPM]":"7.8","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"1.6","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"1.6","Tissue RNA - stomach 1 [nTPM]":"1.1","Tissue RNA - testis [nTPM]":"2.2","Tissue RNA - thalamus [nTPM]":"0.9","Tissue RNA - thymus [nTPM]":"7.9","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"6.2","Tissue RNA - urinary bladder [nTPM]":"1.0","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"1.0","Cell RNA - A-431 [nTPM]":"13.0","Cell RNA - A549 [nTPM]":"14.4","Cell RNA - AF22 [nTPM]":"20.4","Cell RNA - AN3-CA [nTPM]":"12.6","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.9","Cell RNA - BEWO [nTPM]":"14.6","Cell RNA - BJ [nTPM]":"9.4","Cell RNA - BJ hTERT+ [nTPM]":"3.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.4","Cell RNA - CACO-2 [nTPM]":"11.7","Cell RNA - CAPAN-2 [nTPM]":"10.1","Cell RNA - Daudi [nTPM]":"35.1","Cell RNA - EFO-21 [nTPM]":"5.9","Cell RNA - fHDF\/TERT166 [nTPM]":"2.6","Cell RNA - GAMG [nTPM]":"14.1","Cell RNA - HaCaT [nTPM]":"20.4","Cell RNA - HAP1 [nTPM]":"25.7","Cell RNA - HBEC3-KT [nTPM]":"7.1","Cell RNA - HBF TERT88 [nTPM]":"15.1","Cell RNA - HDLM-2 [nTPM]":"19.1","Cell RNA - HEK 293 [nTPM]":"20.5","Cell RNA - HEL [nTPM]":"36.4","Cell RNA - HeLa [nTPM]":"14.8","Cell RNA - Hep G2 [nTPM]":"3.9","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"33.7","Cell RNA - HMC-1 [nTPM]":"17.3","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.6","Cell RNA - hTERT-HME1 [nTPM]":"4.7","Cell RNA - hTERT-RPE1 [nTPM]":"1.3","Cell RNA - HUVEC TERT2 [nTPM]":"7.9","Cell RNA - JURKAT [nTPM]":"16.9","Cell RNA - K-562 [nTPM]":"32.7","Cell RNA - Karpas-707 [nTPM]":"9.9","Cell RNA - LHCN-M2 [nTPM]":"11.0","Cell RNA - MCF7 [nTPM]":"7.4","Cell RNA - MOLT-4 [nTPM]":"28.3","Cell RNA - NB-4 [nTPM]":"14.5","Cell RNA - NTERA-2 [nTPM]":"22.2","Cell RNA - OE19 [nTPM]":"24.9","Cell RNA - PC-3 [nTPM]":"4.2","Cell RNA - REH [nTPM]":"25.4","Cell RNA - RH-30 [nTPM]":"39.1","Cell RNA - RPMI-8226 [nTPM]":"14.7","Cell RNA - RPTEC TERT1 [nTPM]":"2.3","Cell RNA - RT4 [nTPM]":"18.9","Cell RNA - SCLC-21H [nTPM]":"14.6","Cell RNA - SH-SY5Y [nTPM]":"14.7","Cell RNA - SiHa [nTPM]":"8.5","Cell RNA - SK-BR-3 [nTPM]":"11.5","Cell RNA - SK-MEL-30 [nTPM]":"4.8","Cell RNA - SuSa [nTPM]":"18.1","Cell RNA - T-47d [nTPM]":"7.2","Cell RNA - THP-1 [nTPM]":"23.4","Cell RNA - TIME [nTPM]":"3.7","Cell RNA - U-138 MG [nTPM]":"8.6","Cell RNA - U-2 OS [nTPM]":"13.6","Cell RNA - U-2197 [nTPM]":"9.6","Cell RNA - U-251 MG [nTPM]":"21.0","Cell RNA - U-266\/70 [nTPM]":"6.4","Cell RNA - U-266\/84 [nTPM]":"30.4","Cell RNA - U-698 [nTPM]":"39.5","Cell RNA - U-87 MG [nTPM]":"5.6","Cell RNA - U-937 [nTPM]":"25.8","Cell RNA - WM-115 [nTPM]":"15.7","Blood RNA - basophil [nTPM]":"1.7","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"2.6","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"2.6","Blood RNA - memory B-cell [nTPM]":"4.6","Blood RNA - memory CD4 T-cell [nTPM]":"1.4","Blood RNA - memory CD8 T-cell [nTPM]":"2.1","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"2.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.1","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"3.1","Blood RNA - non-classical monocyte [nTPM]":"1.0","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"3.2","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"0.9","Brain RNA - basal ganglia [nTPM]":"1.1","Brain RNA - cerebellum [nTPM]":"2.3","Brain RNA - cerebral cortex [nTPM]":"0.9","Brain RNA - hippocampal formation [nTPM]":"0.8","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"1.2","Brain RNA - midbrain [nTPM]":"1.4","Brain RNA - pons [nTPM]":"1.1","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"0.9","Brain RNA - white matter [nTPM]":"1.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.9","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"12.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"3.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"4.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.5","Single Cell Type RNA - dendritic cells [nTPM]":"6.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.3","Single Cell Type RNA - Endothelial cells [nTPM]":"2.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"18.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.8","Single Cell Type RNA - Fibroblasts [nTPM]":"1.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.7","Single Cell Type RNA - granulocytes [nTPM]":"13.3","Single Cell Type RNA - Granulosa cells [nTPM]":"8.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"7.7","Single Cell Type RNA - Langerhans cells [nTPM]":"1.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"7.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"2.7","Single Cell Type RNA - Muller glia cells [nTPM]":"1.7","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"58.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"20.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.7","Single Cell Type RNA - Spermatocytes [nTPM]":"17.1","Single Cell Type RNA - Spermatogonia [nTPM]":"12.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"10.2","Single Cell Type RNA - Theca cells [nTPM]":"0.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"BLVRA","Gene synonym":["BLVR"],"Ensembl":"ENSG00000106605","Gene description":"Biliverdin reductase A","Uniprot":["P53004"],"Chromosome":"7","Position":"43758680-43807342","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"259.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019709","HPA042865","HPA054322"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1200000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA019709":"AB_2670239","HPA042865":"AB_10797024","HPA054322":"AB_2682450"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.65e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Tissue RNA - adipose tissue [nTPM]":"53.2","Tissue RNA - adrenal gland [nTPM]":"28.0","Tissue RNA - amygdala [nTPM]":"31.4","Tissue RNA - appendix [nTPM]":"39.7","Tissue RNA - basal ganglia [nTPM]":"33.4","Tissue RNA - bone marrow [nTPM]":"65.6","Tissue RNA - breast [nTPM]":"49.9","Tissue RNA - cerebellum [nTPM]":"32.0","Tissue RNA - cerebral cortex [nTPM]":"40.1","Tissue RNA - cervix [nTPM]":"44.3","Tissue RNA - choroid plexus [nTPM]":"31.4","Tissue RNA - colon [nTPM]":"61.4","Tissue RNA - duodenum [nTPM]":"12.5","Tissue RNA - endometrium 1 [nTPM]":"38.5","Tissue RNA - epididymis [nTPM]":"129.9","Tissue RNA - esophagus [nTPM]":"67.5","Tissue RNA - fallopian tube [nTPM]":"40.9","Tissue RNA - gallbladder [nTPM]":"33.4","Tissue RNA - heart muscle [nTPM]":"52.7","Tissue RNA - hippocampal formation [nTPM]":"32.3","Tissue RNA - hypothalamus [nTPM]":"34.7","Tissue RNA - kidney [nTPM]":"41.3","Tissue RNA - liver [nTPM]":"14.6","Tissue RNA - lung [nTPM]":"62.7","Tissue RNA - lymph node [nTPM]":"58.6","Tissue RNA - medulla oblongata [nTPM]":"34.1","Tissue RNA - midbrain [nTPM]":"33.6","Tissue RNA - ovary [nTPM]":"46.6","Tissue RNA - pancreas [nTPM]":"23.5","Tissue RNA - parathyroid gland [nTPM]":"54.9","Tissue RNA - pituitary gland [nTPM]":"26.2","Tissue RNA - placenta [nTPM]":"28.9","Tissue RNA - pons [nTPM]":"34.2","Tissue RNA - prostate [nTPM]":"38.4","Tissue RNA - rectum [nTPM]":"19.8","Tissue RNA - retina [nTPM]":"25.4","Tissue RNA - salivary gland [nTPM]":"36.5","Tissue RNA - seminal vesicle [nTPM]":"46.0","Tissue RNA - skeletal muscle [nTPM]":"59.7","Tissue RNA - skin 1 [nTPM]":"33.4","Tissue RNA - small intestine [nTPM]":"27.7","Tissue RNA - smooth muscle [nTPM]":"54.1","Tissue RNA - spinal cord [nTPM]":"33.1","Tissue RNA - spleen [nTPM]":"82.0","Tissue RNA - stomach 1 [nTPM]":"35.3","Tissue RNA - testis [nTPM]":"13.1","Tissue RNA - thalamus [nTPM]":"34.0","Tissue RNA - thymus [nTPM]":"43.0","Tissue RNA - thyroid gland [nTPM]":"31.3","Tissue RNA - tongue [nTPM]":"69.3","Tissue RNA - tonsil [nTPM]":"52.6","Tissue RNA - urinary bladder [nTPM]":"43.5","Tissue RNA - vagina [nTPM]":"40.4","Tissue RNA - white matter [nTPM]":"32.0","Cell RNA - A-431 [nTPM]":"48.6","Cell RNA - A549 [nTPM]":"92.2","Cell RNA - AF22 [nTPM]":"26.2","Cell RNA - AN3-CA [nTPM]":"110.5","Cell RNA - ASC diff [nTPM]":"55.0","Cell RNA - ASC TERT1 [nTPM]":"72.7","Cell RNA - BEWO [nTPM]":"1.3","Cell RNA - BJ [nTPM]":"32.3","Cell RNA - BJ hTERT+ [nTPM]":"99.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"54.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"65.4","Cell RNA - CACO-2 [nTPM]":"22.2","Cell RNA - CAPAN-2 [nTPM]":"28.3","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"60.6","Cell RNA - fHDF\/TERT166 [nTPM]":"51.5","Cell RNA - GAMG [nTPM]":"190.7","Cell RNA - HaCaT [nTPM]":"62.1","Cell RNA - HAP1 [nTPM]":"82.1","Cell RNA - HBEC3-KT [nTPM]":"81.7","Cell RNA - HBF TERT88 [nTPM]":"46.2","Cell RNA - HDLM-2 [nTPM]":"227.3","Cell RNA - HEK 293 [nTPM]":"56.8","Cell RNA - HEL [nTPM]":"104.1","Cell RNA - HeLa [nTPM]":"86.6","Cell RNA - Hep G2 [nTPM]":"138.1","Cell RNA - HHSteC [nTPM]":"139.5","Cell RNA - HL-60 [nTPM]":"11.8","Cell RNA - HMC-1 [nTPM]":"37.5","Cell RNA - HSkMC [nTPM]":"49.9","Cell RNA - hTCEpi [nTPM]":"135.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"57.2","Cell RNA - hTERT-HME1 [nTPM]":"37.8","Cell RNA - hTERT-RPE1 [nTPM]":"108.5","Cell RNA - HUVEC TERT2 [nTPM]":"92.7","Cell RNA - JURKAT [nTPM]":"51.1","Cell RNA - K-562 [nTPM]":"70.2","Cell RNA - Karpas-707 [nTPM]":"55.7","Cell RNA - LHCN-M2 [nTPM]":"41.4","Cell RNA - MCF7 [nTPM]":"52.5","Cell RNA - MOLT-4 [nTPM]":"37.0","Cell RNA - NB-4 [nTPM]":"6.3","Cell RNA - NTERA-2 [nTPM]":"35.9","Cell RNA - OE19 [nTPM]":"11.0","Cell RNA - PC-3 [nTPM]":"104.7","Cell RNA - REH [nTPM]":"80.4","Cell RNA - RH-30 [nTPM]":"45.6","Cell RNA - RPMI-8226 [nTPM]":"261.4","Cell RNA - RPTEC TERT1 [nTPM]":"121.1","Cell RNA - RT4 [nTPM]":"26.6","Cell RNA - SCLC-21H [nTPM]":"34.0","Cell RNA - SH-SY5Y [nTPM]":"104.4","Cell RNA - SiHa [nTPM]":"65.9","Cell RNA - SK-BR-3 [nTPM]":"65.1","Cell RNA - SK-MEL-30 [nTPM]":"55.2","Cell RNA - SuSa [nTPM]":"46.2","Cell RNA - T-47d [nTPM]":"146.7","Cell RNA - THP-1 [nTPM]":"77.7","Cell RNA - TIME [nTPM]":"57.0","Cell RNA - U-138 MG [nTPM]":"49.3","Cell RNA - U-2 OS [nTPM]":"53.9","Cell RNA - U-2197 [nTPM]":"21.8","Cell RNA - U-251 MG [nTPM]":"56.0","Cell RNA - U-266\/70 [nTPM]":"74.7","Cell RNA - U-266\/84 [nTPM]":"63.2","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"80.8","Cell RNA - U-937 [nTPM]":"46.9","Cell RNA - WM-115 [nTPM]":"78.4","Blood RNA - basophil [nTPM]":"51.1","Blood RNA - classical monocyte [nTPM]":"291.9","Blood RNA - eosinophil [nTPM]":"169.2","Blood RNA - gdT-cell [nTPM]":"39.1","Blood RNA - intermediate monocyte [nTPM]":"374.9","Blood RNA - MAIT T-cell [nTPM]":"36.7","Blood RNA - memory B-cell [nTPM]":"26.9","Blood RNA - memory CD4 T-cell [nTPM]":"75.7","Blood RNA - memory CD8 T-cell [nTPM]":"64.9","Blood RNA - myeloid DC [nTPM]":"135.4","Blood RNA - naive B-cell [nTPM]":"17.0","Blood RNA - naive CD4 T-cell [nTPM]":"39.7","Blood RNA - naive CD8 T-cell [nTPM]":"31.0","Blood RNA - neutrophil [nTPM]":"26.5","Blood RNA - NK-cell [nTPM]":"22.4","Blood RNA - non-classical monocyte [nTPM]":"368.4","Blood RNA - plasmacytoid DC [nTPM]":"20.1","Blood RNA - T-reg [nTPM]":"82.2","Blood RNA - total PBMC [nTPM]":"208.5","Brain RNA - amygdala [nTPM]":"31.4","Brain RNA - basal ganglia [nTPM]":"33.4","Brain RNA - cerebellum [nTPM]":"32.0","Brain RNA - cerebral cortex [nTPM]":"40.1","Brain RNA - hippocampal formation [nTPM]":"32.3","Brain RNA - hypothalamus [nTPM]":"34.7","Brain RNA - medulla oblongata [nTPM]":"34.1","Brain RNA - midbrain [nTPM]":"33.6","Brain RNA - pons [nTPM]":"34.2","Brain RNA - spinal cord [nTPM]":"33.1","Brain RNA - thalamus [nTPM]":"34.0","Brain RNA - white matter [nTPM]":"32.0","Single Cell Type RNA - Adipocytes [nTPM]":"22.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"85.0","Single Cell Type RNA - Astrocytes [nTPM]":"7.5","Single Cell Type RNA - B-cells [nTPM]":"10.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"29.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"64.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"102.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"34.1","Single Cell Type RNA - Bipolar cells [nTPM]":"18.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"36.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"59.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"75.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"35.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.7","Single Cell Type RNA - dendritic cells [nTPM]":"9.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"56.7","Single Cell Type RNA - Ductal cells [nTPM]":"52.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"31.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.2","Single Cell Type RNA - Endothelial cells [nTPM]":"27.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"74.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"35.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.1","Single Cell Type RNA - Fibroblasts [nTPM]":"39.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"41.4","Single Cell Type RNA - granulocytes [nTPM]":"111.5","Single Cell Type RNA - Granulosa cells [nTPM]":"17.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"24.3","Single Cell Type RNA - Hepatocytes [nTPM]":"1.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"259.1","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"59.0","Single Cell Type RNA - Kupffer cells [nTPM]":"136.5","Single Cell Type RNA - Langerhans cells [nTPM]":"53.7","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"37.0","Single Cell Type RNA - Macrophages [nTPM]":"80.4","Single Cell Type RNA - Melanocytes [nTPM]":"46.2","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"147.3","Single Cell Type RNA - Muller glia cells [nTPM]":"36.6","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"25.2","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"29.0","Single Cell Type RNA - Plasma cells [nTPM]":"16.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"87.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"110.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"69.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.0","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"50.6","Single Cell Type RNA - Spermatocytes [nTPM]":"3.0","Single Cell Type RNA - Spermatogonia [nTPM]":"14.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"52.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"34.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.2","Single Cell Type RNA - T-cells [nTPM]":"23.4","Single Cell Type RNA - Theca cells [nTPM]":"4.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"48.7"},{"Gene":"BMP1","Gene synonym":["BMP-1","PCOLC"],"Ensembl":"ENSG00000168487","Gene description":"Bone morphogenetic protein 1","Uniprot":["P13497"],"Chromosome":"8","Position":"22165140-22212326","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted secreted proteins"],"Biological process":["Chondrogenesis","Differentiation","Osteogenesis"],"Molecular function":["Cytokine","Developmental protein","Growth factor","Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant","Osteogenesis imperfecta"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"69.3","Endometrial stromal cells":"52.8","Smooth muscle cells":"43.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014572"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9200000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014572":"AB_1845390"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.75e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.37e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.7","Tissue RNA - adrenal gland [nTPM]":"17.4","Tissue RNA - amygdala [nTPM]":"3.8","Tissue RNA - appendix [nTPM]":"6.3","Tissue RNA - basal ganglia [nTPM]":"4.6","Tissue RNA - bone marrow [nTPM]":"1.4","Tissue RNA - breast [nTPM]":"9.0","Tissue RNA - cerebellum [nTPM]":"4.7","Tissue RNA - cerebral cortex [nTPM]":"4.4","Tissue RNA - cervix [nTPM]":"15.6","Tissue RNA - choroid plexus [nTPM]":"4.9","Tissue RNA - colon [nTPM]":"8.1","Tissue RNA - duodenum [nTPM]":"4.8","Tissue RNA - endometrium 1 [nTPM]":"12.7","Tissue RNA - epididymis [nTPM]":"3.9","Tissue RNA - esophagus [nTPM]":"7.0","Tissue RNA - fallopian tube [nTPM]":"11.8","Tissue RNA - gallbladder [nTPM]":"9.8","Tissue RNA - heart muscle [nTPM]":"5.9","Tissue RNA - hippocampal formation [nTPM]":"4.3","Tissue RNA - hypothalamus [nTPM]":"3.9","Tissue RNA - kidney [nTPM]":"7.7","Tissue RNA - liver [nTPM]":"14.7","Tissue RNA - lung [nTPM]":"8.3","Tissue RNA - lymph node [nTPM]":"1.7","Tissue RNA - medulla oblongata [nTPM]":"5.0","Tissue RNA - midbrain [nTPM]":"4.1","Tissue RNA - ovary [nTPM]":"5.9","Tissue RNA - pancreas [nTPM]":"4.4","Tissue RNA - parathyroid gland [nTPM]":"3.4","Tissue RNA - pituitary gland [nTPM]":"3.4","Tissue RNA - placenta [nTPM]":"27.3","Tissue RNA - pons [nTPM]":"4.1","Tissue RNA - prostate [nTPM]":"9.6","Tissue RNA - rectum [nTPM]":"5.3","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"3.7","Tissue RNA - seminal vesicle [nTPM]":"6.1","Tissue RNA - skeletal muscle [nTPM]":"3.4","Tissue RNA - skin 1 [nTPM]":"6.2","Tissue RNA - small intestine [nTPM]":"5.9","Tissue RNA - smooth muscle [nTPM]":"14.4","Tissue RNA - spinal cord [nTPM]":"4.3","Tissue RNA - spleen [nTPM]":"5.0","Tissue RNA - stomach 1 [nTPM]":"4.3","Tissue RNA - testis [nTPM]":"2.4","Tissue RNA - thalamus [nTPM]":"4.2","Tissue RNA - thymus [nTPM]":"1.5","Tissue RNA - thyroid gland [nTPM]":"10.0","Tissue RNA - tongue [nTPM]":"3.1","Tissue RNA - tonsil [nTPM]":"1.8","Tissue RNA - urinary bladder [nTPM]":"10.4","Tissue RNA - vagina [nTPM]":"10.3","Tissue RNA - white matter [nTPM]":"4.4","Cell RNA - A-431 [nTPM]":"15.2","Cell RNA - A549 [nTPM]":"20.4","Cell RNA - AF22 [nTPM]":"7.4","Cell RNA - AN3-CA [nTPM]":"30.2","Cell RNA - ASC diff [nTPM]":"47.8","Cell RNA - ASC TERT1 [nTPM]":"41.8","Cell RNA - BEWO [nTPM]":"23.2","Cell RNA - BJ [nTPM]":"54.1","Cell RNA - BJ hTERT+ [nTPM]":"50.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"33.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"27.6","Cell RNA - CACO-2 [nTPM]":"5.1","Cell RNA - CAPAN-2 [nTPM]":"27.4","Cell RNA - Daudi [nTPM]":"3.7","Cell RNA - EFO-21 [nTPM]":"32.0","Cell RNA - fHDF\/TERT166 [nTPM]":"56.9","Cell RNA - GAMG [nTPM]":"18.9","Cell RNA - HaCaT [nTPM]":"51.2","Cell RNA - HAP1 [nTPM]":"5.1","Cell RNA - HBEC3-KT [nTPM]":"27.8","Cell RNA - HBF TERT88 [nTPM]":"6.5","Cell RNA - HDLM-2 [nTPM]":"3.6","Cell RNA - HEK 293 [nTPM]":"6.9","Cell RNA - HEL [nTPM]":"6.7","Cell RNA - HeLa [nTPM]":"24.5","Cell RNA - Hep G2 [nTPM]":"7.9","Cell RNA - HHSteC [nTPM]":"31.7","Cell RNA - HL-60 [nTPM]":"2.9","Cell RNA - HMC-1 [nTPM]":"14.3","Cell RNA - HSkMC [nTPM]":"49.8","Cell RNA - hTCEpi [nTPM]":"26.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.2","Cell RNA - hTERT-HME1 [nTPM]":"11.4","Cell RNA - hTERT-RPE1 [nTPM]":"78.3","Cell RNA - HUVEC TERT2 [nTPM]":"31.4","Cell RNA - JURKAT [nTPM]":"5.2","Cell RNA - K-562 [nTPM]":"7.1","Cell RNA - Karpas-707 [nTPM]":"10.6","Cell RNA - LHCN-M2 [nTPM]":"19.6","Cell RNA - MCF7 [nTPM]":"4.6","Cell RNA - MOLT-4 [nTPM]":"1.4","Cell RNA - NB-4 [nTPM]":"3.0","Cell RNA - NTERA-2 [nTPM]":"4.7","Cell RNA - OE19 [nTPM]":"17.0","Cell RNA - PC-3 [nTPM]":"8.3","Cell RNA - REH [nTPM]":"6.4","Cell RNA - RH-30 [nTPM]":"8.2","Cell RNA - RPMI-8226 [nTPM]":"15.2","Cell RNA - RPTEC TERT1 [nTPM]":"26.7","Cell RNA - RT4 [nTPM]":"4.1","Cell RNA - SCLC-21H [nTPM]":"2.8","Cell RNA - SH-SY5Y [nTPM]":"10.6","Cell RNA - SiHa [nTPM]":"52.5","Cell RNA - SK-BR-3 [nTPM]":"3.1","Cell RNA - SK-MEL-30 [nTPM]":"13.4","Cell RNA - SuSa [nTPM]":"20.4","Cell RNA - T-47d [nTPM]":"5.0","Cell RNA - THP-1 [nTPM]":"8.3","Cell RNA - TIME [nTPM]":"41.4","Cell RNA - U-138 MG [nTPM]":"17.0","Cell RNA - U-2 OS [nTPM]":"18.4","Cell RNA - U-2197 [nTPM]":"32.3","Cell RNA - U-251 MG [nTPM]":"23.9","Cell RNA - U-266\/70 [nTPM]":"4.0","Cell RNA - U-266\/84 [nTPM]":"2.2","Cell RNA - U-698 [nTPM]":"0.6","Cell RNA - U-87 MG [nTPM]":"23.8","Cell RNA - U-937 [nTPM]":"10.1","Cell RNA - WM-115 [nTPM]":"28.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"3.8","Brain RNA - basal ganglia [nTPM]":"4.6","Brain RNA - cerebellum [nTPM]":"4.7","Brain RNA - cerebral cortex [nTPM]":"4.4","Brain RNA - hippocampal formation [nTPM]":"4.3","Brain RNA - hypothalamus [nTPM]":"3.9","Brain RNA - medulla oblongata [nTPM]":"5.0","Brain RNA - midbrain [nTPM]":"4.1","Brain RNA - pons [nTPM]":"4.1","Brain RNA - spinal cord [nTPM]":"4.3","Brain RNA - thalamus [nTPM]":"4.2","Brain RNA - white matter [nTPM]":"4.4","Single Cell Type RNA - Adipocytes [nTPM]":"12.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"69.3","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"0.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"2.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"6.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.3","Single Cell Type RNA - dendritic cells [nTPM]":"3.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"31.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"25.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"52.8","Single Cell Type RNA - Endothelial cells [nTPM]":"14.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.5","Single Cell Type RNA - Fibroblasts [nTPM]":"28.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.7","Single Cell Type RNA - granulocytes [nTPM]":"15.2","Single Cell Type RNA - Granulosa cells [nTPM]":"13.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"20.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.3","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.4","Single Cell Type RNA - Langerhans cells [nTPM]":"6.1","Single Cell Type RNA - Late spermatids [nTPM]":"1.1","Single Cell Type RNA - Leydig cells [nTPM]":"10.2","Single Cell Type RNA - Macrophages [nTPM]":"5.4","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.2","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.3","Single Cell Type RNA - Paneth cells [nTPM]":"18.6","Single Cell Type RNA - Peritubular cells [nTPM]":"10.9","Single Cell Type RNA - Plasma cells [nTPM]":"2.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"43.7","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"4.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"24.4","Single Cell Type RNA - T-cells [nTPM]":"3.3","Single Cell Type RNA - Theca cells [nTPM]":"34.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.7","Single Cell Type RNA - Urothelial cells [nTPM]":"8.0"},{"Gene":"BMPR1B","Gene synonym":["ALK6","CDw293"],"Ensembl":"ENSG00000138696","Gene description":"Bone morphogenetic protein receptor type 1B","Uniprot":["O00238"],"Chromosome":"4","Position":"94757955-95158448","Protein class":["CD markers","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Chondrogenesis"],"Molecular function":["Kinase","Receptor","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"20.1","cervix":"24.7","prostate":"22.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Astrocytes":"480.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"32.4","prostate cancer":"24.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"22.0","MCF7":"11.1","SH-SY5Y":"18.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.84e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.7","Tissue RNA - adrenal gland [nTPM]":"4.6","Tissue RNA - amygdala [nTPM]":"13.4","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"15.4","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"1.0","Tissue RNA - cerebellum [nTPM]":"13.5","Tissue RNA - cerebral cortex [nTPM]":"15.0","Tissue RNA - cervix [nTPM]":"24.7","Tissue RNA - choroid plexus [nTPM]":"2.1","Tissue RNA - colon [nTPM]":"0.9","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"4.4","Tissue RNA - epididymis [nTPM]":"2.4","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"12.5","Tissue RNA - gallbladder [nTPM]":"2.6","Tissue RNA - heart muscle [nTPM]":"0.8","Tissue RNA - hippocampal formation [nTPM]":"12.5","Tissue RNA - hypothalamus [nTPM]":"16.0","Tissue RNA - kidney [nTPM]":"7.8","Tissue RNA - liver [nTPM]":"0.8","Tissue RNA - lung [nTPM]":"1.7","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"19.3","Tissue RNA - midbrain [nTPM]":"20.1","Tissue RNA - ovary [nTPM]":"6.2","Tissue RNA - pancreas [nTPM]":"1.1","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"1.9","Tissue RNA - placenta [nTPM]":"0.7","Tissue RNA - pons [nTPM]":"17.5","Tissue RNA - prostate [nTPM]":"22.4","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"8.1","Tissue RNA - salivary gland [nTPM]":"1.0","Tissue RNA - seminal vesicle [nTPM]":"14.2","Tissue RNA - skeletal muscle [nTPM]":"3.0","Tissue RNA - skin 1 [nTPM]":"0.8","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"15.3","Tissue RNA - spleen [nTPM]":"0.9","Tissue RNA - stomach 1 [nTPM]":"2.4","Tissue RNA - testis [nTPM]":"3.7","Tissue RNA - thalamus [nTPM]":"15.6","Tissue RNA - thymus [nTPM]":"6.4","Tissue RNA - thyroid gland [nTPM]":"0.5","Tissue RNA - tongue [nTPM]":"1.1","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"12.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"22.0","Cell RNA - AF22 [nTPM]":"5.6","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"2.3","Cell RNA - ASC TERT1 [nTPM]":"4.8","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.5","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"1.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"1.3","Cell RNA - HAP1 [nTPM]":"3.6","Cell RNA - HBEC3-KT [nTPM]":"8.4","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"4.9","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"1.4","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.6","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"2.7","Cell RNA - hTCEpi [nTPM]":"9.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.8","Cell RNA - hTERT-HME1 [nTPM]":"6.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"7.1","Cell RNA - MCF7 [nTPM]":"11.1","Cell RNA - MOLT-4 [nTPM]":"0.6","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"2.1","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"3.2","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"3.4","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"4.3","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"18.8","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"3.2","Cell RNA - SK-MEL-30 [nTPM]":"3.2","Cell RNA - SuSa [nTPM]":"0.8","Cell RNA - T-47d [nTPM]":"1.7","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"4.0","Cell RNA - U-2 OS [nTPM]":"3.8","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"4.3","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.5","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"13.4","Brain RNA - basal ganglia [nTPM]":"15.4","Brain RNA - cerebellum [nTPM]":"13.5","Brain RNA - cerebral cortex [nTPM]":"15.0","Brain RNA - hippocampal formation [nTPM]":"12.5","Brain RNA - hypothalamus [nTPM]":"16.0","Brain RNA - medulla oblongata [nTPM]":"19.3","Brain RNA - midbrain [nTPM]":"20.1","Brain RNA - pons [nTPM]":"17.5","Brain RNA - spinal cord [nTPM]":"15.3","Brain RNA - thalamus [nTPM]":"15.6","Brain RNA - white matter [nTPM]":"12.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"480.6","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"33.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"60.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"28.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.4","Single Cell Type RNA - Endothelial cells [nTPM]":"1.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"51.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"1.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"38.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.9","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"22.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"38.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"28.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.9","Single Cell Type RNA - Spermatocytes [nTPM]":"1.2","Single Cell Type RNA - Spermatogonia [nTPM]":"10.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"4.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.6"},{"Gene":"BPGM","Gene synonym":[],"Ensembl":"ENSG00000172331","Gene description":"Bisphosphoglycerate mutase","Uniprot":["P07738"],"Chromosome":"7","Position":"134646811-134679816","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Glycolysis"],"Molecular function":["Hydrolase","Isomerase"],"Disease involvement":["Congenital erythrocytosis","Disease variant","Hereditary hemolytic anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"87.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Distal tubular cells":"129.1","Erythroid cells":"456.6","Syncytiotrophoblasts":"368.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"118.2","RT4":"186.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016493","HPA028735"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Nucleoli rim"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"81000000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":["Nucleoli","Nucleoli rim"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA016493":"AB_1845414","HPA028735":"AB_10600791"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.95e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.54e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.4","Tissue RNA - adrenal gland [nTPM]":"12.6","Tissue RNA - amygdala [nTPM]":"16.3","Tissue RNA - appendix [nTPM]":"9.1","Tissue RNA - basal ganglia [nTPM]":"17.1","Tissue RNA - bone marrow [nTPM]":"87.3","Tissue RNA - breast [nTPM]":"12.4","Tissue RNA - cerebellum [nTPM]":"17.9","Tissue RNA - cerebral cortex [nTPM]":"20.5","Tissue RNA - cervix [nTPM]":"12.5","Tissue RNA - choroid plexus [nTPM]":"15.8","Tissue RNA - colon [nTPM]":"12.9","Tissue RNA - duodenum [nTPM]":"8.4","Tissue RNA - endometrium 1 [nTPM]":"9.6","Tissue RNA - epididymis [nTPM]":"18.5","Tissue RNA - esophagus [nTPM]":"26.9","Tissue RNA - fallopian tube [nTPM]":"8.5","Tissue RNA - gallbladder [nTPM]":"12.9","Tissue RNA - heart muscle [nTPM]":"13.5","Tissue RNA - hippocampal formation [nTPM]":"16.5","Tissue RNA - hypothalamus [nTPM]":"19.0","Tissue RNA - kidney [nTPM]":"35.1","Tissue RNA - liver [nTPM]":"13.1","Tissue RNA - lung [nTPM]":"14.0","Tissue RNA - lymph node [nTPM]":"11.1","Tissue RNA - medulla oblongata [nTPM]":"17.9","Tissue RNA - midbrain [nTPM]":"17.8","Tissue RNA - ovary [nTPM]":"7.1","Tissue RNA - pancreas [nTPM]":"8.4","Tissue RNA - parathyroid gland [nTPM]":"35.3","Tissue RNA - pituitary gland [nTPM]":"18.1","Tissue RNA - placenta [nTPM]":"47.0","Tissue RNA - pons [nTPM]":"18.2","Tissue RNA - prostate [nTPM]":"13.5","Tissue RNA - rectum [nTPM]":"10.0","Tissue RNA - retina [nTPM]":"19.9","Tissue RNA - salivary gland [nTPM]":"17.8","Tissue RNA - seminal vesicle [nTPM]":"17.9","Tissue RNA - skeletal muscle [nTPM]":"37.8","Tissue RNA - skin 1 [nTPM]":"10.7","Tissue RNA - small intestine [nTPM]":"8.0","Tissue RNA - smooth muscle [nTPM]":"12.1","Tissue RNA - spinal cord [nTPM]":"19.6","Tissue RNA - spleen [nTPM]":"12.5","Tissue RNA - stomach 1 [nTPM]":"11.9","Tissue RNA - testis [nTPM]":"14.7","Tissue RNA - thalamus [nTPM]":"17.7","Tissue RNA - thymus [nTPM]":"16.3","Tissue RNA - thyroid gland [nTPM]":"11.9","Tissue RNA - tongue [nTPM]":"27.0","Tissue RNA - tonsil [nTPM]":"26.2","Tissue RNA - urinary bladder [nTPM]":"39.0","Tissue RNA - vagina [nTPM]":"17.2","Tissue RNA - white matter [nTPM]":"18.5","Cell RNA - A-431 [nTPM]":"14.0","Cell RNA - A549 [nTPM]":"16.3","Cell RNA - AF22 [nTPM]":"21.7","Cell RNA - AN3-CA [nTPM]":"29.6","Cell RNA - ASC diff [nTPM]":"24.3","Cell RNA - ASC TERT1 [nTPM]":"14.4","Cell RNA - BEWO [nTPM]":"21.9","Cell RNA - BJ [nTPM]":"41.3","Cell RNA - BJ hTERT+ [nTPM]":"49.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.2","Cell RNA - CACO-2 [nTPM]":"6.5","Cell RNA - CAPAN-2 [nTPM]":"18.5","Cell RNA - Daudi [nTPM]":"17.1","Cell RNA - EFO-21 [nTPM]":"12.0","Cell RNA - fHDF\/TERT166 [nTPM]":"23.2","Cell RNA - GAMG [nTPM]":"30.9","Cell RNA - HaCaT [nTPM]":"11.2","Cell RNA - HAP1 [nTPM]":"23.3","Cell RNA - HBEC3-KT [nTPM]":"22.7","Cell RNA - HBF TERT88 [nTPM]":"27.6","Cell RNA - HDLM-2 [nTPM]":"118.2","Cell RNA - HEK 293 [nTPM]":"19.9","Cell RNA - HEL [nTPM]":"9.8","Cell RNA - HeLa [nTPM]":"15.4","Cell RNA - Hep G2 [nTPM]":"7.8","Cell RNA - HHSteC [nTPM]":"16.7","Cell RNA - HL-60 [nTPM]":"18.8","Cell RNA - HMC-1 [nTPM]":"12.4","Cell RNA - HSkMC [nTPM]":"14.2","Cell RNA - hTCEpi [nTPM]":"20.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"29.7","Cell RNA - hTERT-HME1 [nTPM]":"16.0","Cell RNA - hTERT-RPE1 [nTPM]":"24.0","Cell RNA - HUVEC TERT2 [nTPM]":"58.0","Cell RNA - JURKAT [nTPM]":"20.8","Cell RNA - K-562 [nTPM]":"28.8","Cell RNA - Karpas-707 [nTPM]":"20.9","Cell RNA - LHCN-M2 [nTPM]":"37.8","Cell RNA - MCF7 [nTPM]":"6.6","Cell RNA - MOLT-4 [nTPM]":"30.7","Cell RNA - NB-4 [nTPM]":"26.0","Cell RNA - NTERA-2 [nTPM]":"22.7","Cell RNA - OE19 [nTPM]":"27.7","Cell RNA - PC-3 [nTPM]":"15.3","Cell RNA - REH [nTPM]":"23.2","Cell RNA - RH-30 [nTPM]":"15.5","Cell RNA - RPMI-8226 [nTPM]":"12.4","Cell RNA - RPTEC TERT1 [nTPM]":"36.1","Cell RNA - RT4 [nTPM]":"186.8","Cell RNA - SCLC-21H [nTPM]":"18.7","Cell RNA - SH-SY5Y [nTPM]":"31.1","Cell RNA - SiHa [nTPM]":"19.3","Cell RNA - SK-BR-3 [nTPM]":"23.1","Cell RNA - SK-MEL-30 [nTPM]":"21.7","Cell RNA - SuSa [nTPM]":"23.1","Cell RNA - T-47d [nTPM]":"15.1","Cell RNA - THP-1 [nTPM]":"11.8","Cell RNA - TIME [nTPM]":"44.7","Cell RNA - U-138 MG [nTPM]":"25.1","Cell RNA - U-2 OS [nTPM]":"6.0","Cell RNA - U-2197 [nTPM]":"33.7","Cell RNA - U-251 MG [nTPM]":"33.9","Cell RNA - U-266\/70 [nTPM]":"33.9","Cell RNA - U-266\/84 [nTPM]":"41.2","Cell RNA - U-698 [nTPM]":"21.5","Cell RNA - U-87 MG [nTPM]":"43.3","Cell RNA - U-937 [nTPM]":"17.7","Cell RNA - WM-115 [nTPM]":"43.7","Blood RNA - basophil [nTPM]":"61.1","Blood RNA - classical monocyte [nTPM]":"16.4","Blood RNA - eosinophil [nTPM]":"48.9","Blood RNA - gdT-cell [nTPM]":"23.3","Blood RNA - intermediate monocyte [nTPM]":"22.2","Blood RNA - MAIT T-cell [nTPM]":"16.7","Blood RNA - memory B-cell [nTPM]":"19.3","Blood RNA - memory CD4 T-cell [nTPM]":"15.0","Blood RNA - memory CD8 T-cell [nTPM]":"20.7","Blood RNA - myeloid DC [nTPM]":"17.5","Blood RNA - naive B-cell [nTPM]":"18.9","Blood RNA - naive CD4 T-cell [nTPM]":"20.7","Blood RNA - naive CD8 T-cell [nTPM]":"21.1","Blood RNA - neutrophil [nTPM]":"30.2","Blood RNA - NK-cell [nTPM]":"18.5","Blood RNA - non-classical monocyte [nTPM]":"23.0","Blood RNA - plasmacytoid DC [nTPM]":"11.4","Blood RNA - T-reg [nTPM]":"21.1","Blood RNA - total PBMC [nTPM]":"23.6","Brain RNA - amygdala [nTPM]":"16.3","Brain RNA - basal ganglia [nTPM]":"17.1","Brain RNA - cerebellum [nTPM]":"17.9","Brain RNA - cerebral cortex [nTPM]":"20.5","Brain RNA - hippocampal formation [nTPM]":"16.5","Brain RNA - hypothalamus [nTPM]":"19.0","Brain RNA - medulla oblongata [nTPM]":"17.9","Brain RNA - midbrain [nTPM]":"17.8","Brain RNA - pons [nTPM]":"18.2","Brain RNA - spinal cord [nTPM]":"19.6","Brain RNA - thalamus [nTPM]":"17.7","Brain RNA - white matter [nTPM]":"18.5","Single Cell Type RNA - Adipocytes [nTPM]":"17.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.5","Single Cell Type RNA - Astrocytes [nTPM]":"6.5","Single Cell Type RNA - B-cells [nTPM]":"15.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"39.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"60.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"19.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"52.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"44.5","Single Cell Type RNA - dendritic cells [nTPM]":"43.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"129.1","Single Cell Type RNA - Ductal cells [nTPM]":"45.9","Single Cell Type RNA - Early spermatids [nTPM]":"3.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.0","Single Cell Type RNA - Endothelial cells [nTPM]":"18.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"456.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"32.7","Single Cell Type RNA - Fibroblasts [nTPM]":"17.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.5","Single Cell Type RNA - granulocytes [nTPM]":"24.7","Single Cell Type RNA - Granulosa cells [nTPM]":"6.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.0","Single Cell Type RNA - Hepatocytes [nTPM]":"4.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.1","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.6","Single Cell Type RNA - Ionocytes [nTPM]":"36.7","Single Cell Type RNA - Kupffer cells [nTPM]":"11.7","Single Cell Type RNA - Langerhans cells [nTPM]":"10.5","Single Cell Type RNA - Late spermatids [nTPM]":"7.2","Single Cell Type RNA - Leydig cells [nTPM]":"10.2","Single Cell Type RNA - Macrophages [nTPM]":"11.8","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"15.7","Single Cell Type RNA - Muller glia cells [nTPM]":"25.6","Single Cell Type RNA - NK-cells [nTPM]":"47.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"49.0","Single Cell Type RNA - Paneth cells [nTPM]":"4.6","Single Cell Type RNA - Peritubular cells [nTPM]":"12.0","Single Cell Type RNA - Plasma cells [nTPM]":"14.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"26.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"68.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"50.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.1","Single Cell Type RNA - Spermatocytes [nTPM]":"33.9","Single Cell Type RNA - Spermatogonia [nTPM]":"21.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"368.9","Single Cell Type RNA - T-cells [nTPM]":"25.0","Single Cell Type RNA - Theca cells [nTPM]":"7.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.8","Single Cell Type RNA - Urothelial cells [nTPM]":"19.2"},{"Gene":"BPNT2","Gene synonym":["FLJ20421","gPAPP","IMPA3","IMPAD1"],"Ensembl":"ENSG00000104331","Gene description":"3'(2'), 5'-bisphosphate nucleotidase 2","Uniprot":["Q9NX62"],"Chromosome":"8","Position":"56957931-56993867","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"22.6","Cardiomyocytes":"53.8","Cytotrophoblasts":"18.0","dendritic cells":"16.2","Extravillous trophoblasts":"91.8","Hofbauer cells":"26.6","Syncytiotrophoblasts":"33.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009411"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"480000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA009411":"AB_1079138"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Tissue RNA - adipose tissue [nTPM]":"37.6","Tissue RNA - adrenal gland [nTPM]":"37.3","Tissue RNA - amygdala [nTPM]":"14.8","Tissue RNA - appendix [nTPM]":"16.1","Tissue RNA - basal ganglia [nTPM]":"19.9","Tissue RNA - bone marrow [nTPM]":"12.4","Tissue RNA - breast [nTPM]":"19.3","Tissue RNA - cerebellum [nTPM]":"19.2","Tissue RNA - cerebral cortex [nTPM]":"19.8","Tissue RNA - cervix [nTPM]":"25.5","Tissue RNA - choroid plexus [nTPM]":"8.9","Tissue RNA - colon [nTPM]":"17.4","Tissue RNA - duodenum [nTPM]":"13.3","Tissue RNA - endometrium 1 [nTPM]":"21.9","Tissue RNA - epididymis [nTPM]":"16.2","Tissue RNA - esophagus [nTPM]":"19.1","Tissue RNA - fallopian tube [nTPM]":"13.4","Tissue RNA - gallbladder [nTPM]":"16.5","Tissue RNA - heart muscle [nTPM]":"29.4","Tissue RNA - hippocampal formation [nTPM]":"16.0","Tissue RNA - hypothalamus [nTPM]":"17.9","Tissue RNA - kidney [nTPM]":"23.4","Tissue RNA - liver [nTPM]":"36.2","Tissue RNA - lung [nTPM]":"17.2","Tissue RNA - lymph node [nTPM]":"12.3","Tissue RNA - medulla oblongata [nTPM]":"17.2","Tissue RNA - midbrain [nTPM]":"17.6","Tissue RNA - ovary [nTPM]":"11.8","Tissue RNA - pancreas [nTPM]":"19.6","Tissue RNA - parathyroid gland [nTPM]":"35.6","Tissue RNA - pituitary gland [nTPM]":"13.7","Tissue RNA - placenta [nTPM]":"24.9","Tissue RNA - pons [nTPM]":"17.7","Tissue RNA - prostate [nTPM]":"31.0","Tissue RNA - rectum [nTPM]":"17.6","Tissue RNA - retina [nTPM]":"19.7","Tissue RNA - salivary gland [nTPM]":"21.9","Tissue RNA - seminal vesicle [nTPM]":"23.6","Tissue RNA - skeletal muscle [nTPM]":"37.4","Tissue RNA - skin 1 [nTPM]":"14.3","Tissue RNA - small intestine [nTPM]":"12.7","Tissue RNA - smooth muscle [nTPM]":"25.7","Tissue RNA - spinal cord [nTPM]":"15.3","Tissue RNA - spleen [nTPM]":"15.5","Tissue RNA - stomach 1 [nTPM]":"16.9","Tissue RNA - testis [nTPM]":"16.5","Tissue RNA - thalamus [nTPM]":"18.0","Tissue RNA - thymus [nTPM]":"15.4","Tissue RNA - thyroid gland [nTPM]":"27.1","Tissue RNA - tongue [nTPM]":"30.1","Tissue RNA - tonsil [nTPM]":"13.3","Tissue RNA - urinary bladder [nTPM]":"22.4","Tissue RNA - vagina [nTPM]":"12.2","Tissue RNA - white matter [nTPM]":"29.3","Cell RNA - A-431 [nTPM]":"42.4","Cell RNA - A549 [nTPM]":"34.5","Cell RNA - AF22 [nTPM]":"26.0","Cell RNA - AN3-CA [nTPM]":"26.9","Cell RNA - ASC diff [nTPM]":"78.2","Cell RNA - ASC TERT1 [nTPM]":"53.3","Cell RNA - BEWO [nTPM]":"35.7","Cell RNA - BJ [nTPM]":"62.9","Cell RNA - BJ hTERT+ [nTPM]":"60.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"44.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"38.3","Cell RNA - CACO-2 [nTPM]":"17.4","Cell RNA - CAPAN-2 [nTPM]":"29.2","Cell RNA - Daudi [nTPM]":"26.3","Cell RNA - EFO-21 [nTPM]":"47.0","Cell RNA - fHDF\/TERT166 [nTPM]":"67.3","Cell RNA - GAMG [nTPM]":"31.2","Cell RNA - HaCaT [nTPM]":"33.7","Cell RNA - HAP1 [nTPM]":"31.8","Cell RNA - HBEC3-KT [nTPM]":"42.5","Cell RNA - HBF TERT88 [nTPM]":"65.0","Cell RNA - HDLM-2 [nTPM]":"36.4","Cell RNA - HEK 293 [nTPM]":"22.7","Cell RNA - HEL [nTPM]":"51.4","Cell RNA - HeLa [nTPM]":"23.0","Cell RNA - Hep G2 [nTPM]":"31.2","Cell RNA - HHSteC [nTPM]":"48.5","Cell RNA - HL-60 [nTPM]":"33.0","Cell RNA - HMC-1 [nTPM]":"35.1","Cell RNA - HSkMC [nTPM]":"43.2","Cell RNA - hTCEpi [nTPM]":"41.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"39.7","Cell RNA - hTERT-HME1 [nTPM]":"63.9","Cell RNA - hTERT-RPE1 [nTPM]":"40.8","Cell RNA - HUVEC TERT2 [nTPM]":"59.5","Cell RNA - JURKAT [nTPM]":"24.3","Cell RNA - K-562 [nTPM]":"22.5","Cell RNA - Karpas-707 [nTPM]":"46.1","Cell RNA - LHCN-M2 [nTPM]":"48.9","Cell RNA - MCF7 [nTPM]":"22.1","Cell RNA - MOLT-4 [nTPM]":"40.6","Cell RNA - NB-4 [nTPM]":"19.8","Cell RNA - NTERA-2 [nTPM]":"19.2","Cell RNA - OE19 [nTPM]":"48.1","Cell RNA - PC-3 [nTPM]":"12.7","Cell RNA - REH [nTPM]":"27.9","Cell RNA - RH-30 [nTPM]":"23.4","Cell RNA - RPMI-8226 [nTPM]":"29.7","Cell RNA - RPTEC TERT1 [nTPM]":"46.0","Cell RNA - RT4 [nTPM]":"24.9","Cell RNA - SCLC-21H [nTPM]":"10.1","Cell RNA - SH-SY5Y [nTPM]":"28.1","Cell RNA - SiHa [nTPM]":"35.3","Cell RNA - SK-BR-3 [nTPM]":"42.9","Cell RNA - SK-MEL-30 [nTPM]":"36.3","Cell RNA - SuSa [nTPM]":"27.1","Cell RNA - T-47d [nTPM]":"38.4","Cell RNA - THP-1 [nTPM]":"23.9","Cell RNA - TIME [nTPM]":"50.1","Cell RNA - U-138 MG [nTPM]":"59.3","Cell RNA - U-2 OS [nTPM]":"34.2","Cell RNA - U-2197 [nTPM]":"59.2","Cell RNA - U-251 MG [nTPM]":"45.8","Cell RNA - U-266\/70 [nTPM]":"47.5","Cell RNA - U-266\/84 [nTPM]":"42.5","Cell RNA - U-698 [nTPM]":"27.8","Cell RNA - U-87 MG [nTPM]":"81.0","Cell RNA - U-937 [nTPM]":"27.0","Cell RNA - WM-115 [nTPM]":"37.3","Blood RNA - basophil [nTPM]":"1.8","Blood RNA - classical monocyte [nTPM]":"0.9","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.9","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"0.9","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"1.1","Blood RNA - neutrophil [nTPM]":"2.5","Blood RNA - NK-cell [nTPM]":"3.2","Blood RNA - non-classical monocyte [nTPM]":"2.6","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"14.8","Brain RNA - basal ganglia [nTPM]":"19.9","Brain RNA - cerebellum [nTPM]":"19.2","Brain RNA - cerebral cortex [nTPM]":"19.8","Brain RNA - hippocampal formation [nTPM]":"16.0","Brain RNA - hypothalamus [nTPM]":"17.9","Brain RNA - medulla oblongata [nTPM]":"17.2","Brain RNA - midbrain [nTPM]":"17.6","Brain RNA - pons [nTPM]":"17.7","Brain RNA - spinal cord [nTPM]":"15.3","Brain RNA - thalamus [nTPM]":"18.0","Brain RNA - white matter [nTPM]":"29.3","Single Cell Type RNA - Adipocytes [nTPM]":"22.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"53.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.0","Single Cell Type RNA - dendritic cells [nTPM]":"16.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"6.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"91.8","Single Cell Type RNA - Fibroblasts [nTPM]":"14.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"26.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"3.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"5.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"33.8","Single Cell Type RNA - T-cells [nTPM]":"1.8","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"BRCA1","Gene synonym":["BRCC1","FANCS","PPP1R53","RNF53"],"Ensembl":"ENSG00000012048","Gene description":"BRCA1 DNA repair associated","Uniprot":["P38398"],"Chromosome":"17","Position":"43044295-43170245","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA damage","DNA recombination","DNA repair","Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism","Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["Activator","DNA-binding","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Fanconi anemia","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"42.5","Granulosa cells":"38.2","Spermatocytes":"105.8","Spermatogonia":"73.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"6.8","classical monocyte":"14.7","intermediate monocyte":"4.7","myeloid DC":"10.9","neutrophil":"11.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"10.9","granulocytes":"11.3","monocytes":"14.7"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB001946","HPA004840","HPA034966","HPA057371"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"CAB001946":null,"HPA004840":null,"HPA034966":"AB_10795287","HPA057371":"AB_2732611"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.62e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.31e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.1","Tissue RNA - adrenal gland [nTPM]":"1.8","Tissue RNA - amygdala [nTPM]":"4.2","Tissue RNA - appendix [nTPM]":"7.5","Tissue RNA - basal ganglia [nTPM]":"7.2","Tissue RNA - bone marrow [nTPM]":"13.0","Tissue RNA - breast [nTPM]":"3.6","Tissue RNA - cerebellum [nTPM]":"4.7","Tissue RNA - cerebral cortex [nTPM]":"5.2","Tissue RNA - cervix [nTPM]":"2.7","Tissue RNA - choroid plexus [nTPM]":"2.7","Tissue RNA - colon [nTPM]":"6.8","Tissue RNA - duodenum [nTPM]":"3.2","Tissue RNA - endometrium 1 [nTPM]":"3.1","Tissue RNA - epididymis [nTPM]":"2.2","Tissue RNA - esophagus [nTPM]":"4.0","Tissue RNA - fallopian tube [nTPM]":"3.7","Tissue RNA - gallbladder [nTPM]":"1.9","Tissue RNA - heart muscle [nTPM]":"3.0","Tissue RNA - hippocampal formation [nTPM]":"3.6","Tissue RNA - hypothalamus [nTPM]":"4.1","Tissue RNA - kidney [nTPM]":"2.0","Tissue RNA - liver [nTPM]":"5.6","Tissue RNA - lung [nTPM]":"3.2","Tissue RNA - lymph node [nTPM]":"10.3","Tissue RNA - medulla oblongata [nTPM]":"5.6","Tissue RNA - midbrain [nTPM]":"5.0","Tissue RNA - ovary [nTPM]":"2.8","Tissue RNA - pancreas [nTPM]":"2.8","Tissue RNA - parathyroid gland [nTPM]":"5.9","Tissue RNA - pituitary gland [nTPM]":"2.8","Tissue RNA - placenta [nTPM]":"3.8","Tissue RNA - pons [nTPM]":"6.0","Tissue RNA - prostate [nTPM]":"2.4","Tissue RNA - rectum [nTPM]":"7.4","Tissue RNA - retina [nTPM]":"8.2","Tissue RNA - salivary gland [nTPM]":"3.2","Tissue RNA - seminal vesicle [nTPM]":"1.6","Tissue RNA - skeletal muscle [nTPM]":"4.2","Tissue RNA - skin 1 [nTPM]":"6.0","Tissue RNA - small intestine [nTPM]":"5.1","Tissue RNA - smooth muscle [nTPM]":"3.9","Tissue RNA - spinal cord [nTPM]":"3.7","Tissue RNA - spleen [nTPM]":"3.9","Tissue RNA - stomach 1 [nTPM]":"3.6","Tissue RNA - testis [nTPM]":"13.0","Tissue RNA - thalamus [nTPM]":"5.5","Tissue RNA - thymus [nTPM]":"14.5","Tissue RNA - thyroid gland [nTPM]":"7.8","Tissue RNA - tongue [nTPM]":"3.7","Tissue RNA - tonsil [nTPM]":"11.2","Tissue RNA - urinary bladder [nTPM]":"2.8","Tissue RNA - vagina [nTPM]":"2.4","Tissue RNA - white matter [nTPM]":"10.8","Cell RNA - A-431 [nTPM]":"44.1","Cell RNA - A549 [nTPM]":"69.1","Cell RNA - AF22 [nTPM]":"37.8","Cell RNA - AN3-CA [nTPM]":"30.1","Cell RNA - ASC diff [nTPM]":"6.0","Cell RNA - ASC TERT1 [nTPM]":"13.4","Cell RNA - BEWO [nTPM]":"36.6","Cell RNA - BJ [nTPM]":"50.6","Cell RNA - BJ hTERT+ [nTPM]":"21.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"41.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"39.3","Cell RNA - CACO-2 [nTPM]":"42.3","Cell RNA - CAPAN-2 [nTPM]":"33.4","Cell RNA - Daudi [nTPM]":"100.8","Cell RNA - EFO-21 [nTPM]":"9.1","Cell RNA - fHDF\/TERT166 [nTPM]":"19.0","Cell RNA - GAMG [nTPM]":"49.0","Cell RNA - HaCaT [nTPM]":"49.5","Cell RNA - HAP1 [nTPM]":"51.9","Cell RNA - HBEC3-KT [nTPM]":"28.3","Cell RNA - HBF TERT88 [nTPM]":"69.5","Cell RNA - HDLM-2 [nTPM]":"46.9","Cell RNA - HEK 293 [nTPM]":"38.0","Cell RNA - HEL [nTPM]":"48.1","Cell RNA - HeLa [nTPM]":"54.0","Cell RNA - Hep G2 [nTPM]":"37.1","Cell RNA - HHSteC [nTPM]":"1.3","Cell RNA - HL-60 [nTPM]":"86.0","Cell RNA - HMC-1 [nTPM]":"39.9","Cell RNA - HSkMC [nTPM]":"3.8","Cell RNA - hTCEpi [nTPM]":"4.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"63.1","Cell RNA - hTERT-HME1 [nTPM]":"20.0","Cell RNA - hTERT-RPE1 [nTPM]":"10.6","Cell RNA - HUVEC TERT2 [nTPM]":"22.3","Cell RNA - JURKAT [nTPM]":"46.6","Cell RNA - K-562 [nTPM]":"73.7","Cell RNA - Karpas-707 [nTPM]":"42.2","Cell RNA - LHCN-M2 [nTPM]":"39.7","Cell RNA - MCF7 [nTPM]":"30.0","Cell RNA - MOLT-4 [nTPM]":"72.0","Cell RNA - NB-4 [nTPM]":"27.8","Cell RNA - NTERA-2 [nTPM]":"20.5","Cell RNA - OE19 [nTPM]":"29.1","Cell RNA - PC-3 [nTPM]":"18.7","Cell RNA - REH [nTPM]":"49.0","Cell RNA - RH-30 [nTPM]":"79.8","Cell RNA - RPMI-8226 [nTPM]":"40.8","Cell RNA - RPTEC TERT1 [nTPM]":"15.4","Cell RNA - RT4 [nTPM]":"42.1","Cell RNA - SCLC-21H [nTPM]":"25.8","Cell RNA - SH-SY5Y [nTPM]":"27.4","Cell RNA - SiHa [nTPM]":"38.8","Cell RNA - SK-BR-3 [nTPM]":"12.5","Cell RNA - SK-MEL-30 [nTPM]":"19.4","Cell RNA - SuSa [nTPM]":"25.5","Cell RNA - T-47d [nTPM]":"33.9","Cell RNA - THP-1 [nTPM]":"39.6","Cell RNA - TIME [nTPM]":"13.8","Cell RNA - U-138 MG [nTPM]":"37.2","Cell RNA - U-2 OS [nTPM]":"29.6","Cell RNA - U-2197 [nTPM]":"49.0","Cell RNA - U-251 MG [nTPM]":"53.2","Cell RNA - U-266\/70 [nTPM]":"20.1","Cell RNA - U-266\/84 [nTPM]":"51.2","Cell RNA - U-698 [nTPM]":"75.5","Cell RNA - U-87 MG [nTPM]":"29.6","Cell RNA - U-937 [nTPM]":"49.6","Cell RNA - WM-115 [nTPM]":"39.4","Blood RNA - basophil [nTPM]":"6.8","Blood RNA - classical monocyte [nTPM]":"14.7","Blood RNA - eosinophil [nTPM]":"2.2","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"4.7","Blood RNA - MAIT T-cell [nTPM]":"1.5","Blood RNA - memory B-cell [nTPM]":"1.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"1.2","Blood RNA - myeloid DC [nTPM]":"10.9","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"11.3","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"2.0","Blood RNA - plasmacytoid DC [nTPM]":"1.7","Blood RNA - T-reg [nTPM]":"0.5","Blood RNA - total PBMC [nTPM]":"17.5","Brain RNA - amygdala [nTPM]":"4.2","Brain RNA - basal ganglia [nTPM]":"7.2","Brain RNA - cerebellum [nTPM]":"4.7","Brain RNA - cerebral cortex [nTPM]":"5.2","Brain RNA - hippocampal formation [nTPM]":"3.6","Brain RNA - hypothalamus [nTPM]":"4.1","Brain RNA - medulla oblongata [nTPM]":"5.6","Brain RNA - midbrain [nTPM]":"5.0","Brain RNA - pons [nTPM]":"6.0","Brain RNA - spinal cord [nTPM]":"3.7","Brain RNA - thalamus [nTPM]":"5.5","Brain RNA - white matter [nTPM]":"10.8","Single Cell Type RNA - Adipocytes [nTPM]":"5.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.8","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"5.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"10.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"3.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.8","Single Cell Type RNA - dendritic cells [nTPM]":"8.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.0","Single Cell Type RNA - Early spermatids [nTPM]":"11.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.3","Single Cell Type RNA - Endothelial cells [nTPM]":"4.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"42.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.2","Single Cell Type RNA - Fibroblasts [nTPM]":"7.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.2","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"38.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"18.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.1","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.9","Single Cell Type RNA - Langerhans cells [nTPM]":"2.8","Single Cell Type RNA - Late spermatids [nTPM]":"8.0","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"6.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"4.9","Single Cell Type RNA - Muller glia cells [nTPM]":"2.4","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.7","Single Cell Type RNA - Paneth cells [nTPM]":"2.4","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"16.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"22.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.5","Single Cell Type RNA - Spermatocytes [nTPM]":"105.8","Single Cell Type RNA - Spermatogonia [nTPM]":"73.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.0","Single Cell Type RNA - T-cells [nTPM]":"4.7","Single Cell Type RNA - Theca cells [nTPM]":"9.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.7","Single Cell Type RNA - Urothelial cells [nTPM]":"3.4"},{"Gene":"BRCC3","Gene synonym":["BRCC36","C6.1A","CXorf53"],"Ensembl":"ENSG00000185515","Gene description":"BRCA1\/BRCA2-containing complex subunit 3","Uniprot":["P46736"],"Chromosome":"X","Position":"155071420-155123077","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","DNA damage","DNA repair","Mitosis","Ubl conjugation pathway"],"Molecular function":["Chromatin regulator","Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048737"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA048737":"AB_2680504"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.9","Tissue RNA - adrenal gland [nTPM]":"12.9","Tissue RNA - amygdala [nTPM]":"6.8","Tissue RNA - appendix [nTPM]":"12.1","Tissue RNA - basal ganglia [nTPM]":"6.6","Tissue RNA - bone marrow [nTPM]":"15.6","Tissue RNA - breast [nTPM]":"15.8","Tissue RNA - cerebellum [nTPM]":"9.2","Tissue RNA - cerebral cortex [nTPM]":"7.7","Tissue RNA - cervix [nTPM]":"12.8","Tissue RNA - choroid plexus [nTPM]":"6.8","Tissue RNA - colon [nTPM]":"22.3","Tissue RNA - duodenum [nTPM]":"19.3","Tissue RNA - endometrium 1 [nTPM]":"9.2","Tissue RNA - epididymis [nTPM]":"18.5","Tissue RNA - esophagus [nTPM]":"18.4","Tissue RNA - fallopian tube [nTPM]":"11.6","Tissue RNA - gallbladder [nTPM]":"8.4","Tissue RNA - heart muscle [nTPM]":"11.2","Tissue RNA - hippocampal formation [nTPM]":"6.6","Tissue RNA - hypothalamus [nTPM]":"7.0","Tissue RNA - kidney [nTPM]":"17.8","Tissue RNA - liver [nTPM]":"13.8","Tissue RNA - lung [nTPM]":"9.8","Tissue RNA - lymph node [nTPM]":"15.4","Tissue RNA - medulla oblongata [nTPM]":"5.9","Tissue RNA - midbrain [nTPM]":"7.1","Tissue RNA - ovary [nTPM]":"8.1","Tissue RNA - pancreas [nTPM]":"11.4","Tissue RNA - parathyroid gland [nTPM]":"14.7","Tissue RNA - pituitary gland [nTPM]":"5.2","Tissue RNA - placenta [nTPM]":"14.0","Tissue RNA - pons [nTPM]":"6.7","Tissue RNA - prostate [nTPM]":"14.6","Tissue RNA - rectum [nTPM]":"23.3","Tissue RNA - retina [nTPM]":"12.9","Tissue RNA - salivary gland [nTPM]":"18.5","Tissue RNA - seminal vesicle [nTPM]":"10.9","Tissue RNA - skeletal muscle [nTPM]":"17.8","Tissue RNA - skin 1 [nTPM]":"11.1","Tissue RNA - small intestine [nTPM]":"16.9","Tissue RNA - smooth muscle [nTPM]":"10.6","Tissue RNA - spinal cord [nTPM]":"5.4","Tissue RNA - spleen [nTPM]":"11.0","Tissue RNA - stomach 1 [nTPM]":"15.6","Tissue RNA - testis [nTPM]":"2.3","Tissue RNA - thalamus [nTPM]":"7.4","Tissue RNA - thymus [nTPM]":"13.4","Tissue RNA - thyroid gland [nTPM]":"15.2","Tissue RNA - tongue [nTPM]":"17.6","Tissue RNA - tonsil [nTPM]":"15.5","Tissue RNA - urinary bladder [nTPM]":"12.6","Tissue RNA - vagina [nTPM]":"6.3","Tissue RNA - white matter [nTPM]":"6.6","Cell RNA - A-431 [nTPM]":"95.6","Cell RNA - A549 [nTPM]":"45.1","Cell RNA - AF22 [nTPM]":"24.4","Cell RNA - AN3-CA [nTPM]":"19.6","Cell RNA - ASC diff [nTPM]":"20.9","Cell RNA - ASC TERT1 [nTPM]":"17.7","Cell RNA - BEWO [nTPM]":"37.9","Cell RNA - BJ [nTPM]":"35.9","Cell RNA - BJ hTERT+ [nTPM]":"25.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"52.3","Cell RNA - CACO-2 [nTPM]":"44.0","Cell RNA - CAPAN-2 [nTPM]":"40.1","Cell RNA - Daudi [nTPM]":"84.1","Cell RNA - EFO-21 [nTPM]":"62.8","Cell RNA - fHDF\/TERT166 [nTPM]":"22.1","Cell RNA - GAMG [nTPM]":"36.1","Cell RNA - HaCaT [nTPM]":"36.3","Cell RNA - HAP1 [nTPM]":"54.4","Cell RNA - HBEC3-KT [nTPM]":"33.6","Cell RNA - HBF TERT88 [nTPM]":"38.0","Cell RNA - HDLM-2 [nTPM]":"45.4","Cell RNA - HEK 293 [nTPM]":"42.1","Cell RNA - HEL [nTPM]":"17.7","Cell RNA - HeLa [nTPM]":"76.1","Cell RNA - Hep G2 [nTPM]":"41.4","Cell RNA - HHSteC [nTPM]":"15.8","Cell RNA - HL-60 [nTPM]":"62.8","Cell RNA - HMC-1 [nTPM]":"25.5","Cell RNA - HSkMC [nTPM]":"17.3","Cell RNA - hTCEpi [nTPM]":"16.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"35.1","Cell RNA - hTERT-HME1 [nTPM]":"28.5","Cell RNA - hTERT-RPE1 [nTPM]":"23.1","Cell RNA - HUVEC TERT2 [nTPM]":"30.1","Cell RNA - JURKAT [nTPM]":"32.2","Cell RNA - K-562 [nTPM]":"27.4","Cell RNA - Karpas-707 [nTPM]":"24.9","Cell RNA - LHCN-M2 [nTPM]":"24.6","Cell RNA - MCF7 [nTPM]":"33.6","Cell RNA - MOLT-4 [nTPM]":"25.8","Cell RNA - NB-4 [nTPM]":"28.8","Cell RNA - NTERA-2 [nTPM]":"22.3","Cell RNA - OE19 [nTPM]":"101.9","Cell RNA - PC-3 [nTPM]":"41.9","Cell RNA - REH [nTPM]":"36.2","Cell RNA - RH-30 [nTPM]":"43.3","Cell RNA - RPMI-8226 [nTPM]":"42.0","Cell RNA - RPTEC TERT1 [nTPM]":"36.8","Cell RNA - RT4 [nTPM]":"36.5","Cell RNA - SCLC-21H [nTPM]":"38.0","Cell RNA - SH-SY5Y [nTPM]":"17.3","Cell RNA - SiHa [nTPM]":"25.6","Cell RNA - SK-BR-3 [nTPM]":"43.6","Cell RNA - SK-MEL-30 [nTPM]":"27.3","Cell RNA - SuSa [nTPM]":"31.5","Cell RNA - T-47d [nTPM]":"25.2","Cell RNA - THP-1 [nTPM]":"33.7","Cell RNA - TIME [nTPM]":"31.5","Cell RNA - U-138 MG [nTPM]":"20.4","Cell RNA - U-2 OS [nTPM]":"32.1","Cell RNA - U-2197 [nTPM]":"27.6","Cell RNA - U-251 MG [nTPM]":"53.8","Cell RNA - U-266\/70 [nTPM]":"30.0","Cell RNA - U-266\/84 [nTPM]":"56.1","Cell RNA - U-698 [nTPM]":"114.5","Cell RNA - U-87 MG [nTPM]":"28.2","Cell RNA - U-937 [nTPM]":"61.5","Cell RNA - WM-115 [nTPM]":"25.3","Blood RNA - basophil [nTPM]":"36.8","Blood RNA - classical monocyte [nTPM]":"18.8","Blood RNA - eosinophil [nTPM]":"34.0","Blood RNA - gdT-cell [nTPM]":"20.0","Blood RNA - intermediate monocyte [nTPM]":"22.9","Blood RNA - MAIT T-cell [nTPM]":"23.4","Blood RNA - memory B-cell [nTPM]":"17.6","Blood RNA - memory CD4 T-cell [nTPM]":"19.3","Blood RNA - memory CD8 T-cell [nTPM]":"18.2","Blood RNA - myeloid DC [nTPM]":"21.2","Blood RNA - naive B-cell [nTPM]":"16.7","Blood RNA - naive CD4 T-cell [nTPM]":"14.8","Blood RNA - naive CD8 T-cell [nTPM]":"16.6","Blood RNA - neutrophil [nTPM]":"10.5","Blood RNA - NK-cell [nTPM]":"28.4","Blood RNA - non-classical monocyte [nTPM]":"24.1","Blood RNA - plasmacytoid DC [nTPM]":"13.3","Blood RNA - T-reg [nTPM]":"25.4","Blood RNA - total PBMC [nTPM]":"16.9","Brain RNA - amygdala [nTPM]":"6.8","Brain RNA - basal ganglia [nTPM]":"6.6","Brain RNA - cerebellum [nTPM]":"9.2","Brain RNA - cerebral cortex [nTPM]":"7.7","Brain RNA - hippocampal formation [nTPM]":"6.6","Brain RNA - hypothalamus [nTPM]":"7.0","Brain RNA - medulla oblongata [nTPM]":"5.9","Brain RNA - midbrain [nTPM]":"7.1","Brain RNA - pons [nTPM]":"6.7","Brain RNA - spinal cord [nTPM]":"5.4","Brain RNA - thalamus [nTPM]":"7.4","Brain RNA - white matter [nTPM]":"6.6","Single Cell Type RNA - Adipocytes [nTPM]":"12.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.3","Single Cell Type RNA - Astrocytes [nTPM]":"16.6","Single Cell Type RNA - B-cells [nTPM]":"14.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"13.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"27.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"28.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"26.7","Single Cell Type RNA - dendritic cells [nTPM]":"17.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"25.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"22.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.7","Single Cell Type RNA - Endothelial cells [nTPM]":"10.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"17.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"31.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.6","Single Cell Type RNA - Fibroblasts [nTPM]":"11.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.9","Single Cell Type RNA - granulocytes [nTPM]":"26.6","Single Cell Type RNA - Granulosa cells [nTPM]":"13.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.6","Single Cell Type RNA - Hepatocytes [nTPM]":"8.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.4","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"35.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"22.6","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"9.5","Single Cell Type RNA - Langerhans cells [nTPM]":"7.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"5.9","Single Cell Type RNA - Macrophages [nTPM]":"14.5","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"22.3","Single Cell Type RNA - Muller glia cells [nTPM]":"12.9","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"26.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"29.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.7","Single Cell Type RNA - Paneth cells [nTPM]":"16.8","Single Cell Type RNA - Peritubular cells [nTPM]":"12.0","Single Cell Type RNA - Plasma cells [nTPM]":"21.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"16.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"25.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.5","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.9","Single Cell Type RNA - Spermatocytes [nTPM]":"1.2","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"13.5","Single Cell Type RNA - T-cells [nTPM]":"14.9","Single Cell Type RNA - Theca cells [nTPM]":"18.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"27.3","Single Cell Type RNA - Urothelial cells [nTPM]":"8.3"},{"Gene":"BRIP1","Gene synonym":["BACH1","FANCJ","OF"],"Ensembl":"ENSG00000136492","Gene description":"BRCA1 interacting protein C-terminal helicase 1","Uniprot":["Q9BX63"],"Chromosome":"17","Position":"61679139-61863528","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["Helicase","Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Fanconi anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"7.2","lymphoid tissue":"5.9","testis":"7.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Early spermatids":"186.2","Late spermatids":"194.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"88.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005474"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 23: Spermatids - Flagellum & Golgi organization","Subcellular main location":["Nucleoplasm","Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA005474":"AB_2667333"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.45e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.62e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"0.8","Tissue RNA - appendix [nTPM]":"1.7","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"7.2","Tissue RNA - breast [nTPM]":"0.9","Tissue RNA - cerebellum [nTPM]":"1.3","Tissue RNA - cerebral cortex [nTPM]":"0.9","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.7","Tissue RNA - duodenum [nTPM]":"2.0","Tissue RNA - endometrium 1 [nTPM]":"0.8","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"1.5","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.6","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"1.6","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"2.8","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"1.1","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.8","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"1.9","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"2.0","Tissue RNA - small intestine [nTPM]":"1.9","Tissue RNA - smooth muscle [nTPM]":"0.9","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.7","Tissue RNA - stomach 1 [nTPM]":"0.9","Tissue RNA - testis [nTPM]":"7.0","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"5.9","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"3.3","Tissue RNA - urinary bladder [nTPM]":"0.7","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"0.8","Cell RNA - A-431 [nTPM]":"26.6","Cell RNA - A549 [nTPM]":"9.4","Cell RNA - AF22 [nTPM]":"25.0","Cell RNA - AN3-CA [nTPM]":"14.1","Cell RNA - ASC diff [nTPM]":"0.9","Cell RNA - ASC TERT1 [nTPM]":"2.1","Cell RNA - BEWO [nTPM]":"5.5","Cell RNA - BJ [nTPM]":"23.6","Cell RNA - BJ hTERT+ [nTPM]":"13.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"31.8","Cell RNA - CACO-2 [nTPM]":"9.5","Cell RNA - CAPAN-2 [nTPM]":"8.0","Cell RNA - Daudi [nTPM]":"14.9","Cell RNA - EFO-21 [nTPM]":"5.2","Cell RNA - fHDF\/TERT166 [nTPM]":"4.9","Cell RNA - GAMG [nTPM]":"7.7","Cell RNA - HaCaT [nTPM]":"9.2","Cell RNA - HAP1 [nTPM]":"12.8","Cell RNA - HBEC3-KT [nTPM]":"4.5","Cell RNA - HBF TERT88 [nTPM]":"33.3","Cell RNA - HDLM-2 [nTPM]":"3.8","Cell RNA - HEK 293 [nTPM]":"15.8","Cell RNA - HEL [nTPM]":"15.5","Cell RNA - HeLa [nTPM]":"14.4","Cell RNA - Hep G2 [nTPM]":"10.5","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"20.3","Cell RNA - HMC-1 [nTPM]":"8.8","Cell RNA - HSkMC [nTPM]":"0.6","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.2","Cell RNA - hTERT-HME1 [nTPM]":"5.1","Cell RNA - hTERT-RPE1 [nTPM]":"3.4","Cell RNA - HUVEC TERT2 [nTPM]":"5.0","Cell RNA - JURKAT [nTPM]":"14.8","Cell RNA - K-562 [nTPM]":"11.6","Cell RNA - Karpas-707 [nTPM]":"10.5","Cell RNA - LHCN-M2 [nTPM]":"14.4","Cell RNA - MCF7 [nTPM]":"88.9","Cell RNA - MOLT-4 [nTPM]":"32.5","Cell RNA - NB-4 [nTPM]":"6.7","Cell RNA - NTERA-2 [nTPM]":"5.3","Cell RNA - OE19 [nTPM]":"5.9","Cell RNA - PC-3 [nTPM]":"7.3","Cell RNA - REH [nTPM]":"19.7","Cell RNA - RH-30 [nTPM]":"50.1","Cell RNA - RPMI-8226 [nTPM]":"7.1","Cell RNA - RPTEC TERT1 [nTPM]":"3.0","Cell RNA - RT4 [nTPM]":"12.8","Cell RNA - SCLC-21H [nTPM]":"10.0","Cell RNA - SH-SY5Y [nTPM]":"24.2","Cell RNA - SiHa [nTPM]":"9.4","Cell RNA - SK-BR-3 [nTPM]":"3.0","Cell RNA - SK-MEL-30 [nTPM]":"3.3","Cell RNA - SuSa [nTPM]":"9.1","Cell RNA - T-47d [nTPM]":"8.3","Cell RNA - THP-1 [nTPM]":"7.3","Cell RNA - TIME [nTPM]":"4.5","Cell RNA - U-138 MG [nTPM]":"36.9","Cell RNA - U-2 OS [nTPM]":"26.5","Cell RNA - U-2197 [nTPM]":"13.5","Cell RNA - U-251 MG [nTPM]":"26.6","Cell RNA - U-266\/70 [nTPM]":"6.3","Cell RNA - U-266\/84 [nTPM]":"13.3","Cell RNA - U-698 [nTPM]":"16.6","Cell RNA - U-87 MG [nTPM]":"7.3","Cell RNA - U-937 [nTPM]":"9.3","Cell RNA - WM-115 [nTPM]":"8.8","Blood RNA - basophil [nTPM]":"1.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"1.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.8","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"1.3","Brain RNA - cerebral cortex [nTPM]":"0.9","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"1.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"4.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.0","Single Cell Type RNA - dendritic cells [nTPM]":"2.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"186.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.7","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"15.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"3.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"1.1","Single Cell Type RNA - Late spermatids [nTPM]":"194.1","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"4.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.8","Single Cell Type RNA - Spermatocytes [nTPM]":"12.1","Single Cell Type RNA - Spermatogonia [nTPM]":"6.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"2.3","Single Cell Type RNA - Theca cells [nTPM]":"2.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.7","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"BSCL2","Gene synonym":["GNG3LG","seipin","SPG17"],"Ensembl":"ENSG00000168000","Gene description":"BSCL2 lipid droplet biogenesis associated, seipin","Uniprot":["Q96G97"],"Chromosome":"11","Position":"62690275-62709845","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":null,"Disease involvement":["Congenital generalized lipodystrophy","Diabetes mellitus","Disease variant","Hereditary spastic paraplegia","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"292.1","pituitary gland":"237.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"35.9","Late spermatids":"53.1","Plasma cells":"86.3","Spermatocytes":"32.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"242.1","RPMI-8226":"176.1","SCLC-21H":"181.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042394"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042394":"AB_10794047"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.55e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Tissue RNA - adipose tissue [nTPM]":"24.9","Tissue RNA - adrenal gland [nTPM]":"88.1","Tissue RNA - amygdala [nTPM]":"126.6","Tissue RNA - appendix [nTPM]":"7.4","Tissue RNA - basal ganglia [nTPM]":"133.2","Tissue RNA - bone marrow [nTPM]":"12.0","Tissue RNA - breast [nTPM]":"26.2","Tissue RNA - cerebellum [nTPM]":"75.0","Tissue RNA - cerebral cortex [nTPM]":"155.6","Tissue RNA - cervix [nTPM]":"38.2","Tissue RNA - choroid plexus [nTPM]":"85.4","Tissue RNA - colon [nTPM]":"24.3","Tissue RNA - duodenum [nTPM]":"10.8","Tissue RNA - endometrium 1 [nTPM]":"28.4","Tissue RNA - epididymis [nTPM]":"156.7","Tissue RNA - esophagus [nTPM]":"24.1","Tissue RNA - fallopian tube [nTPM]":"63.7","Tissue RNA - gallbladder [nTPM]":"21.5","Tissue RNA - heart muscle [nTPM]":"18.7","Tissue RNA - hippocampal formation [nTPM]":"134.9","Tissue RNA - hypothalamus [nTPM]":"292.1","Tissue RNA - kidney [nTPM]":"50.8","Tissue RNA - liver [nTPM]":"39.3","Tissue RNA - lung [nTPM]":"26.7","Tissue RNA - lymph node [nTPM]":"15.3","Tissue RNA - medulla oblongata [nTPM]":"138.1","Tissue RNA - midbrain [nTPM]":"139.0","Tissue RNA - ovary [nTPM]":"32.7","Tissue RNA - pancreas [nTPM]":"79.4","Tissue RNA - parathyroid gland [nTPM]":"61.7","Tissue RNA - pituitary gland [nTPM]":"237.0","Tissue RNA - placenta [nTPM]":"10.0","Tissue RNA - pons [nTPM]":"203.4","Tissue RNA - prostate [nTPM]":"35.4","Tissue RNA - rectum [nTPM]":"13.3","Tissue RNA - retina [nTPM]":"52.6","Tissue RNA - salivary gland [nTPM]":"66.1","Tissue RNA - seminal vesicle [nTPM]":"30.3","Tissue RNA - skeletal muscle [nTPM]":"30.9","Tissue RNA - skin 1 [nTPM]":"25.1","Tissue RNA - small intestine [nTPM]":"17.2","Tissue RNA - smooth muscle [nTPM]":"13.7","Tissue RNA - spinal cord [nTPM]":"83.1","Tissue RNA - spleen [nTPM]":"16.2","Tissue RNA - stomach 1 [nTPM]":"37.1","Tissue RNA - testis [nTPM]":"190.3","Tissue RNA - thalamus [nTPM]":"169.3","Tissue RNA - thymus [nTPM]":"14.4","Tissue RNA - thyroid gland [nTPM]":"37.9","Tissue RNA - tongue [nTPM]":"15.5","Tissue RNA - tonsil [nTPM]":"8.9","Tissue RNA - urinary bladder [nTPM]":"17.5","Tissue RNA - vagina [nTPM]":"26.1","Tissue RNA - white matter [nTPM]":"89.9","Cell RNA - A-431 [nTPM]":"18.0","Cell RNA - A549 [nTPM]":"61.7","Cell RNA - AF22 [nTPM]":"49.6","Cell RNA - AN3-CA [nTPM]":"83.8","Cell RNA - ASC diff [nTPM]":"130.8","Cell RNA - ASC TERT1 [nTPM]":"41.5","Cell RNA - BEWO [nTPM]":"7.2","Cell RNA - BJ [nTPM]":"7.2","Cell RNA - BJ hTERT+ [nTPM]":"34.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.5","Cell RNA - CACO-2 [nTPM]":"9.6","Cell RNA - CAPAN-2 [nTPM]":"26.3","Cell RNA - Daudi [nTPM]":"11.9","Cell RNA - EFO-21 [nTPM]":"16.5","Cell RNA - fHDF\/TERT166 [nTPM]":"25.2","Cell RNA - GAMG [nTPM]":"11.8","Cell RNA - HaCaT [nTPM]":"62.1","Cell RNA - HAP1 [nTPM]":"5.2","Cell RNA - HBEC3-KT [nTPM]":"21.8","Cell RNA - HBF TERT88 [nTPM]":"7.0","Cell RNA - HDLM-2 [nTPM]":"30.7","Cell RNA - HEK 293 [nTPM]":"5.0","Cell RNA - HEL [nTPM]":"10.9","Cell RNA - HeLa [nTPM]":"33.4","Cell RNA - Hep G2 [nTPM]":"7.8","Cell RNA - HHSteC [nTPM]":"27.7","Cell RNA - HL-60 [nTPM]":"9.7","Cell RNA - HMC-1 [nTPM]":"13.5","Cell RNA - HSkMC [nTPM]":"27.8","Cell RNA - hTCEpi [nTPM]":"16.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.9","Cell RNA - hTERT-HME1 [nTPM]":"10.9","Cell RNA - hTERT-RPE1 [nTPM]":"19.7","Cell RNA - HUVEC TERT2 [nTPM]":"10.8","Cell RNA - JURKAT [nTPM]":"33.0","Cell RNA - K-562 [nTPM]":"7.8","Cell RNA - Karpas-707 [nTPM]":"242.1","Cell RNA - LHCN-M2 [nTPM]":"19.8","Cell RNA - MCF7 [nTPM]":"44.0","Cell RNA - MOLT-4 [nTPM]":"11.4","Cell RNA - NB-4 [nTPM]":"21.8","Cell RNA - NTERA-2 [nTPM]":"132.4","Cell RNA - OE19 [nTPM]":"13.9","Cell RNA - PC-3 [nTPM]":"13.0","Cell RNA - REH [nTPM]":"21.3","Cell RNA - RH-30 [nTPM]":"4.2","Cell RNA - RPMI-8226 [nTPM]":"176.1","Cell RNA - RPTEC TERT1 [nTPM]":"65.0","Cell RNA - RT4 [nTPM]":"2.4","Cell RNA - SCLC-21H [nTPM]":"181.2","Cell RNA - SH-SY5Y [nTPM]":"29.4","Cell RNA - SiHa [nTPM]":"28.2","Cell RNA - SK-BR-3 [nTPM]":"13.9","Cell RNA - SK-MEL-30 [nTPM]":"25.3","Cell RNA - SuSa [nTPM]":"5.7","Cell RNA - T-47d [nTPM]":"41.3","Cell RNA - THP-1 [nTPM]":"15.3","Cell RNA - TIME [nTPM]":"6.5","Cell RNA - U-138 MG [nTPM]":"16.5","Cell RNA - U-2 OS [nTPM]":"3.7","Cell RNA - U-2197 [nTPM]":"24.5","Cell RNA - U-251 MG [nTPM]":"4.2","Cell RNA - U-266\/70 [nTPM]":"32.2","Cell RNA - U-266\/84 [nTPM]":"72.5","Cell RNA - U-698 [nTPM]":"16.6","Cell RNA - U-87 MG [nTPM]":"82.4","Cell RNA - U-937 [nTPM]":"3.2","Cell RNA - WM-115 [nTPM]":"14.5","Blood RNA - basophil [nTPM]":"26.6","Blood RNA - classical monocyte [nTPM]":"59.2","Blood RNA - eosinophil [nTPM]":"34.6","Blood RNA - gdT-cell [nTPM]":"24.7","Blood RNA - intermediate monocyte [nTPM]":"46.2","Blood RNA - MAIT T-cell [nTPM]":"27.4","Blood RNA - memory B-cell [nTPM]":"27.5","Blood RNA - memory CD4 T-cell [nTPM]":"25.5","Blood RNA - memory CD8 T-cell [nTPM]":"26.1","Blood RNA - myeloid DC [nTPM]":"42.4","Blood RNA - naive B-cell [nTPM]":"29.7","Blood RNA - naive CD4 T-cell [nTPM]":"25.7","Blood RNA - naive CD8 T-cell [nTPM]":"27.0","Blood RNA - neutrophil [nTPM]":"14.2","Blood RNA - NK-cell [nTPM]":"41.0","Blood RNA - non-classical monocyte [nTPM]":"40.3","Blood RNA - plasmacytoid DC [nTPM]":"54.3","Blood RNA - T-reg [nTPM]":"33.1","Blood RNA - total PBMC [nTPM]":"43.3","Brain RNA - amygdala [nTPM]":"126.6","Brain RNA - basal ganglia [nTPM]":"133.2","Brain RNA - cerebellum [nTPM]":"75.0","Brain RNA - cerebral cortex [nTPM]":"155.6","Brain RNA - hippocampal formation [nTPM]":"134.9","Brain RNA - hypothalamus [nTPM]":"292.1","Brain RNA - medulla oblongata [nTPM]":"138.1","Brain RNA - midbrain [nTPM]":"139.0","Brain RNA - pons [nTPM]":"203.4","Brain RNA - spinal cord [nTPM]":"83.1","Brain RNA - thalamus [nTPM]":"169.3","Brain RNA - white matter [nTPM]":"89.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"7.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"35.9","Single Cell Type RNA - Bipolar cells [nTPM]":"2.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"1.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.0","Single Cell Type RNA - Early spermatids [nTPM]":"25.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.5","Single Cell Type RNA - Endothelial cells [nTPM]":"2.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"8.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.9","Single Cell Type RNA - Fibroblasts [nTPM]":"9.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.5","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"2.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.9","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.6","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"2.5","Single Cell Type RNA - Langerhans cells [nTPM]":"3.1","Single Cell Type RNA - Late spermatids [nTPM]":"53.1","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"6.2","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"1.6","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"86.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.1","Single Cell Type RNA - Spermatocytes [nTPM]":"32.6","Single Cell Type RNA - Spermatogonia [nTPM]":"18.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"24.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - T-cells [nTPM]":"6.5","Single Cell Type RNA - Theca cells [nTPM]":"0.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.5"},{"Gene":"BSND","Gene synonym":["BART","DFNB73"],"Ensembl":"ENSG00000162399","Gene description":"Barttin CLCNK type accessory subunit beta","Uniprot":["Q8WZ55"],"Chromosome":"1","Position":"54998933-55017172","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Bartter syndrome","Deafness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"kidney":"9.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Distal tubular cells":"25.4","Ionocytes":"87.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"renal cancer":"3.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"25","RNA cell line specific nTPM":{"RPMI-8226":"4.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053836","HPA060617"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053836":"AB_2682277","HPA060617":"AB_2732651"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"9.4","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"1.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"1.5","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"4.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"25.4","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"87.5","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"BTD","Gene synonym":[],"Ensembl":"ENSG00000169814","Gene description":"Biotinidase","Uniprot":["P43251"],"Chromosome":"3","Position":"15601341-15722311","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"95.9"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052275"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2800000000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052275":"AB_2681782"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.60e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Tissue RNA - adipose tissue [nTPM]":"25.3","Tissue RNA - adrenal gland [nTPM]":"16.7","Tissue RNA - amygdala [nTPM]":"10.7","Tissue RNA - appendix [nTPM]":"8.0","Tissue RNA - basal ganglia [nTPM]":"12.7","Tissue RNA - bone marrow [nTPM]":"13.1","Tissue RNA - breast [nTPM]":"16.4","Tissue RNA - cerebellum [nTPM]":"20.2","Tissue RNA - cerebral cortex [nTPM]":"12.6","Tissue RNA - cervix [nTPM]":"13.7","Tissue RNA - choroid plexus [nTPM]":"11.0","Tissue RNA - colon [nTPM]":"15.9","Tissue RNA - duodenum [nTPM]":"46.1","Tissue RNA - endometrium 1 [nTPM]":"13.2","Tissue RNA - epididymis [nTPM]":"62.4","Tissue RNA - esophagus [nTPM]":"9.9","Tissue RNA - fallopian tube [nTPM]":"18.3","Tissue RNA - gallbladder [nTPM]":"19.9","Tissue RNA - heart muscle [nTPM]":"10.2","Tissue RNA - hippocampal formation [nTPM]":"11.5","Tissue RNA - hypothalamus [nTPM]":"10.3","Tissue RNA - kidney [nTPM]":"37.6","Tissue RNA - liver [nTPM]":"95.9","Tissue RNA - lung [nTPM]":"15.9","Tissue RNA - lymph node [nTPM]":"9.6","Tissue RNA - medulla oblongata [nTPM]":"12.0","Tissue RNA - midbrain [nTPM]":"10.0","Tissue RNA - ovary [nTPM]":"25.3","Tissue RNA - pancreas [nTPM]":"44.1","Tissue RNA - parathyroid gland [nTPM]":"27.7","Tissue RNA - pituitary gland [nTPM]":"5.9","Tissue RNA - placenta [nTPM]":"17.0","Tissue RNA - pons [nTPM]":"12.6","Tissue RNA - prostate [nTPM]":"19.5","Tissue RNA - rectum [nTPM]":"17.0","Tissue RNA - retina [nTPM]":"35.2","Tissue RNA - salivary gland [nTPM]":"16.0","Tissue RNA - seminal vesicle [nTPM]":"21.1","Tissue RNA - skeletal muscle [nTPM]":"7.8","Tissue RNA - skin 1 [nTPM]":"9.5","Tissue RNA - small intestine [nTPM]":"30.7","Tissue RNA - smooth muscle [nTPM]":"14.1","Tissue RNA - spinal cord [nTPM]":"10.3","Tissue RNA - spleen [nTPM]":"11.3","Tissue RNA - stomach 1 [nTPM]":"24.4","Tissue RNA - testis [nTPM]":"18.2","Tissue RNA - thalamus [nTPM]":"9.9","Tissue RNA - thymus [nTPM]":"10.6","Tissue RNA - thyroid gland [nTPM]":"26.8","Tissue RNA - tongue [nTPM]":"11.4","Tissue RNA - tonsil [nTPM]":"10.4","Tissue RNA - urinary bladder [nTPM]":"14.3","Tissue RNA - vagina [nTPM]":"7.5","Tissue RNA - white matter [nTPM]":"19.1","Cell RNA - A-431 [nTPM]":"9.2","Cell RNA - A549 [nTPM]":"22.0","Cell RNA - AF22 [nTPM]":"7.8","Cell RNA - AN3-CA [nTPM]":"7.3","Cell RNA - ASC diff [nTPM]":"51.7","Cell RNA - ASC TERT1 [nTPM]":"15.3","Cell RNA - BEWO [nTPM]":"39.6","Cell RNA - BJ [nTPM]":"15.4","Cell RNA - BJ hTERT+ [nTPM]":"18.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"28.3","Cell RNA - CACO-2 [nTPM]":"10.1","Cell RNA - CAPAN-2 [nTPM]":"21.5","Cell RNA - Daudi [nTPM]":"4.1","Cell RNA - EFO-21 [nTPM]":"16.3","Cell RNA - fHDF\/TERT166 [nTPM]":"31.6","Cell RNA - GAMG [nTPM]":"7.1","Cell RNA - HaCaT [nTPM]":"9.7","Cell RNA - HAP1 [nTPM]":"5.3","Cell RNA - HBEC3-KT [nTPM]":"16.7","Cell RNA - HBF TERT88 [nTPM]":"18.7","Cell RNA - HDLM-2 [nTPM]":"7.6","Cell RNA - HEK 293 [nTPM]":"11.7","Cell RNA - HEL [nTPM]":"12.9","Cell RNA - HeLa [nTPM]":"28.8","Cell RNA - Hep G2 [nTPM]":"24.8","Cell RNA - HHSteC [nTPM]":"12.7","Cell RNA - HL-60 [nTPM]":"8.8","Cell RNA - HMC-1 [nTPM]":"14.7","Cell RNA - HSkMC [nTPM]":"18.3","Cell RNA - hTCEpi [nTPM]":"16.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"42.9","Cell RNA - hTERT-HME1 [nTPM]":"5.1","Cell RNA - hTERT-RPE1 [nTPM]":"39.7","Cell RNA - HUVEC TERT2 [nTPM]":"30.5","Cell RNA - JURKAT [nTPM]":"5.9","Cell RNA - K-562 [nTPM]":"8.7","Cell RNA - Karpas-707 [nTPM]":"32.3","Cell RNA - LHCN-M2 [nTPM]":"44.7","Cell RNA - MCF7 [nTPM]":"11.1","Cell RNA - MOLT-4 [nTPM]":"4.5","Cell RNA - NB-4 [nTPM]":"8.2","Cell RNA - NTERA-2 [nTPM]":"8.5","Cell RNA - OE19 [nTPM]":"16.9","Cell RNA - PC-3 [nTPM]":"13.0","Cell RNA - REH [nTPM]":"5.9","Cell RNA - RH-30 [nTPM]":"18.4","Cell RNA - RPMI-8226 [nTPM]":"27.9","Cell RNA - RPTEC TERT1 [nTPM]":"16.5","Cell RNA - RT4 [nTPM]":"17.7","Cell RNA - SCLC-21H [nTPM]":"5.3","Cell RNA - SH-SY5Y [nTPM]":"11.8","Cell RNA - SiHa [nTPM]":"17.9","Cell RNA - SK-BR-3 [nTPM]":"5.2","Cell RNA - SK-MEL-30 [nTPM]":"24.4","Cell RNA - SuSa [nTPM]":"15.1","Cell RNA - T-47d [nTPM]":"19.9","Cell RNA - THP-1 [nTPM]":"11.3","Cell RNA - TIME [nTPM]":"24.3","Cell RNA - U-138 MG [nTPM]":"20.5","Cell RNA - U-2 OS [nTPM]":"13.6","Cell RNA - U-2197 [nTPM]":"19.1","Cell RNA - U-251 MG [nTPM]":"10.1","Cell RNA - U-266\/70 [nTPM]":"8.9","Cell RNA - U-266\/84 [nTPM]":"11.4","Cell RNA - U-698 [nTPM]":"4.1","Cell RNA - U-87 MG [nTPM]":"21.4","Cell RNA - U-937 [nTPM]":"7.7","Cell RNA - WM-115 [nTPM]":"14.4","Blood RNA - basophil [nTPM]":"74.1","Blood RNA - classical monocyte [nTPM]":"20.7","Blood RNA - eosinophil [nTPM]":"44.9","Blood RNA - gdT-cell [nTPM]":"22.9","Blood RNA - intermediate monocyte [nTPM]":"19.6","Blood RNA - MAIT T-cell [nTPM]":"21.0","Blood RNA - memory B-cell [nTPM]":"14.7","Blood RNA - memory CD4 T-cell [nTPM]":"23.3","Blood RNA - memory CD8 T-cell [nTPM]":"19.2","Blood RNA - myeloid DC [nTPM]":"21.4","Blood RNA - naive B-cell [nTPM]":"13.1","Blood RNA - naive CD4 T-cell [nTPM]":"19.7","Blood RNA - naive CD8 T-cell [nTPM]":"15.4","Blood RNA - neutrophil [nTPM]":"19.8","Blood RNA - NK-cell [nTPM]":"15.0","Blood RNA - non-classical monocyte [nTPM]":"15.8","Blood RNA - plasmacytoid DC [nTPM]":"24.9","Blood RNA - T-reg [nTPM]":"28.8","Blood RNA - total PBMC [nTPM]":"16.5","Brain RNA - amygdala [nTPM]":"10.7","Brain RNA - basal ganglia [nTPM]":"12.7","Brain RNA - cerebellum [nTPM]":"20.2","Brain RNA - cerebral cortex [nTPM]":"12.6","Brain RNA - hippocampal formation [nTPM]":"11.5","Brain RNA - hypothalamus [nTPM]":"10.3","Brain RNA - medulla oblongata [nTPM]":"12.0","Brain RNA - midbrain [nTPM]":"10.0","Brain RNA - pons [nTPM]":"12.6","Brain RNA - spinal cord [nTPM]":"10.3","Brain RNA - thalamus [nTPM]":"9.9","Brain RNA - white matter [nTPM]":"19.1","Single Cell Type RNA - Adipocytes [nTPM]":"14.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.0","Single Cell Type RNA - Astrocytes [nTPM]":"11.8","Single Cell Type RNA - B-cells [nTPM]":"11.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"25.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"13.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"45.8","Single Cell Type RNA - Club cells [nTPM]":"16.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.3","Single Cell Type RNA - dendritic cells [nTPM]":"19.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"21.1","Single Cell Type RNA - Early spermatids [nTPM]":"31.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.0","Single Cell Type RNA - Endothelial cells [nTPM]":"9.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"4.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"28.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"22.4","Single Cell Type RNA - Fibroblasts [nTPM]":"14.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.7","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"8.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.3","Single Cell Type RNA - Hepatocytes [nTPM]":"63.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.9","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.5","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"8.2","Single Cell Type RNA - Langerhans cells [nTPM]":"5.9","Single Cell Type RNA - Late spermatids [nTPM]":"17.9","Single Cell Type RNA - Leydig cells [nTPM]":"32.3","Single Cell Type RNA - Macrophages [nTPM]":"9.2","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"8.7","Single Cell Type RNA - Muller glia cells [nTPM]":"19.2","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"27.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"23.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.0","Single Cell Type RNA - Paneth cells [nTPM]":"17.9","Single Cell Type RNA - Peritubular cells [nTPM]":"18.0","Single Cell Type RNA - Plasma cells [nTPM]":"16.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"52.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"32.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"54.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.6","Single Cell Type RNA - Spermatocytes [nTPM]":"45.3","Single Cell Type RNA - Spermatogonia [nTPM]":"7.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.1","Single Cell Type RNA - T-cells [nTPM]":"13.6","Single Cell Type RNA - Theca cells [nTPM]":"17.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.9","Single Cell Type RNA - Urothelial cells [nTPM]":"9.5"},{"Gene":"BUB1B","Gene synonym":["Bub1A","BUBR1","MAD3L","SSK1"],"Ensembl":"ENSG00000156970","Gene description":"BUB1 mitotic checkpoint serine\/threonine kinase B","Uniprot":["O60566"],"Chromosome":"15","Position":"40161023-40221123","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Cell cycle","Cell division","Mitosis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"17.8","lymphoid tissue":"35.7","testis":"22.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"23.5","Spermatocytes":"79.2","Spermatogonia":"26.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"1.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008419"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA008419":"AB_1078308"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.43e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.56e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.79e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"6.7","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"17.8","Tissue RNA - breast [nTPM]":"1.6","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"1.0","Tissue RNA - choroid plexus [nTPM]":"7.7","Tissue RNA - colon [nTPM]":"4.6","Tissue RNA - duodenum [nTPM]":"4.7","Tissue RNA - endometrium 1 [nTPM]":"1.2","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"5.2","Tissue RNA - fallopian tube [nTPM]":"0.6","Tissue RNA - gallbladder [nTPM]":"0.6","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"12.6","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"3.4","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"6.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.9","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"3.5","Tissue RNA - small intestine [nTPM]":"4.1","Tissue RNA - smooth muscle [nTPM]":"2.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"3.1","Tissue RNA - stomach 1 [nTPM]":"2.4","Tissue RNA - testis [nTPM]":"22.2","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"35.7","Tissue RNA - thyroid gland [nTPM]":"0.5","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"15.0","Tissue RNA - urinary bladder [nTPM]":"1.5","Tissue RNA - vagina [nTPM]":"1.7","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"66.5","Cell RNA - A549 [nTPM]":"32.8","Cell RNA - AF22 [nTPM]":"103.0","Cell RNA - AN3-CA [nTPM]":"41.5","Cell RNA - ASC diff [nTPM]":"2.5","Cell RNA - ASC TERT1 [nTPM]":"7.1","Cell RNA - BEWO [nTPM]":"33.2","Cell RNA - BJ [nTPM]":"60.9","Cell RNA - BJ hTERT+ [nTPM]":"34.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"64.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"55.7","Cell RNA - CACO-2 [nTPM]":"48.1","Cell RNA - CAPAN-2 [nTPM]":"25.0","Cell RNA - Daudi [nTPM]":"59.7","Cell RNA - EFO-21 [nTPM]":"33.5","Cell RNA - fHDF\/TERT166 [nTPM]":"22.7","Cell RNA - GAMG [nTPM]":"59.0","Cell RNA - HaCaT [nTPM]":"72.6","Cell RNA - HAP1 [nTPM]":"98.8","Cell RNA - HBEC3-KT [nTPM]":"33.2","Cell RNA - HBF TERT88 [nTPM]":"70.5","Cell RNA - HDLM-2 [nTPM]":"51.8","Cell RNA - HEK 293 [nTPM]":"52.1","Cell RNA - HEL [nTPM]":"86.4","Cell RNA - HeLa [nTPM]":"83.6","Cell RNA - Hep G2 [nTPM]":"45.5","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"79.0","Cell RNA - HMC-1 [nTPM]":"45.7","Cell RNA - HSkMC [nTPM]":"1.6","Cell RNA - hTCEpi [nTPM]":"2.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"39.2","Cell RNA - hTERT-HME1 [nTPM]":"37.1","Cell RNA - hTERT-RPE1 [nTPM]":"12.9","Cell RNA - HUVEC TERT2 [nTPM]":"47.7","Cell RNA - JURKAT [nTPM]":"66.5","Cell RNA - K-562 [nTPM]":"76.4","Cell RNA - Karpas-707 [nTPM]":"61.7","Cell RNA - LHCN-M2 [nTPM]":"65.6","Cell RNA - MCF7 [nTPM]":"22.5","Cell RNA - MOLT-4 [nTPM]":"62.5","Cell RNA - NB-4 [nTPM]":"48.9","Cell RNA - NTERA-2 [nTPM]":"70.2","Cell RNA - OE19 [nTPM]":"55.6","Cell RNA - PC-3 [nTPM]":"36.8","Cell RNA - REH [nTPM]":"66.5","Cell RNA - RH-30 [nTPM]":"83.7","Cell RNA - RPMI-8226 [nTPM]":"45.2","Cell RNA - RPTEC TERT1 [nTPM]":"19.9","Cell RNA - RT4 [nTPM]":"33.1","Cell RNA - SCLC-21H [nTPM]":"67.1","Cell RNA - SH-SY5Y [nTPM]":"40.8","Cell RNA - SiHa [nTPM]":"38.0","Cell RNA - SK-BR-3 [nTPM]":"35.9","Cell RNA - SK-MEL-30 [nTPM]":"13.3","Cell RNA - SuSa [nTPM]":"45.1","Cell RNA - T-47d [nTPM]":"41.9","Cell RNA - THP-1 [nTPM]":"40.9","Cell RNA - TIME [nTPM]":"27.6","Cell RNA - U-138 MG [nTPM]":"49.3","Cell RNA - U-2 OS [nTPM]":"51.8","Cell RNA - U-2197 [nTPM]":"49.2","Cell RNA - U-251 MG [nTPM]":"55.5","Cell RNA - U-266\/70 [nTPM]":"32.1","Cell RNA - U-266\/84 [nTPM]":"58.2","Cell RNA - U-698 [nTPM]":"95.6","Cell RNA - U-87 MG [nTPM]":"26.3","Cell RNA - U-937 [nTPM]":"87.8","Cell RNA - WM-115 [nTPM]":"65.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"1.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"3.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.4","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"23.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.7","Single Cell Type RNA - Fibroblasts [nTPM]":"2.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"12.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"1.7","Single Cell Type RNA - Late spermatids [nTPM]":"3.3","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"1.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"1.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"12.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.7","Single Cell Type RNA - Spermatocytes [nTPM]":"79.2","Single Cell Type RNA - Spermatogonia [nTPM]":"26.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"1.8","Single Cell Type RNA - Theca cells [nTPM]":"0.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.4","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"BVES","Gene synonym":["HBVES","POP1","POPDC1"],"Ensembl":"ENSG00000112276","Gene description":"Blood vessel epicardial substance","Uniprot":["Q8NE79"],"Chromosome":"6","Position":"105096822-105137157","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion"],"Molecular function":["Developmental protein"],"Disease involvement":["Limb-girdle muscular dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"27.8","skeletal muscle":"43.9","tongue":"29.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"34.2","Early spermatids":"36.1","Late spermatids":"55.3","Oligodendrocytes":"17.8","Spermatocytes":"24.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RH-30":"29.7","WM-115":"30.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014788","HPA018176"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA014788":"AB_1845504","HPA018176":"AB_1845503"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.84e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-4"},"Tissue RNA - adipose tissue [nTPM]":"2.9","Tissue RNA - adrenal gland [nTPM]":"0.7","Tissue RNA - amygdala [nTPM]":"2.6","Tissue RNA - appendix [nTPM]":"2.3","Tissue RNA - basal ganglia [nTPM]":"7.1","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"1.5","Tissue RNA - cerebellum [nTPM]":"5.8","Tissue RNA - cerebral cortex [nTPM]":"3.6","Tissue RNA - cervix [nTPM]":"2.5","Tissue RNA - choroid plexus [nTPM]":"4.6","Tissue RNA - colon [nTPM]":"14.9","Tissue RNA - duodenum [nTPM]":"1.4","Tissue RNA - endometrium 1 [nTPM]":"5.8","Tissue RNA - epididymis [nTPM]":"1.7","Tissue RNA - esophagus [nTPM]":"5.3","Tissue RNA - fallopian tube [nTPM]":"2.8","Tissue RNA - gallbladder [nTPM]":"1.8","Tissue RNA - heart muscle [nTPM]":"27.8","Tissue RNA - hippocampal formation [nTPM]":"2.7","Tissue RNA - hypothalamus [nTPM]":"4.3","Tissue RNA - kidney [nTPM]":"1.6","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"1.9","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"7.3","Tissue RNA - midbrain [nTPM]":"5.6","Tissue RNA - ovary [nTPM]":"1.0","Tissue RNA - pancreas [nTPM]":"0.6","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"2.4","Tissue RNA - placenta [nTPM]":"3.5","Tissue RNA - pons [nTPM]":"7.4","Tissue RNA - prostate [nTPM]":"5.2","Tissue RNA - rectum [nTPM]":"3.3","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"1.4","Tissue RNA - seminal vesicle [nTPM]":"10.0","Tissue RNA - skeletal muscle [nTPM]":"43.9","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"3.0","Tissue RNA - smooth muscle [nTPM]":"17.7","Tissue RNA - spinal cord [nTPM]":"5.2","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"6.9","Tissue RNA - testis [nTPM]":"11.5","Tissue RNA - thalamus [nTPM]":"5.2","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"1.3","Tissue RNA - tongue [nTPM]":"29.3","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"9.3","Tissue RNA - vagina [nTPM]":"2.2","Tissue RNA - white matter [nTPM]":"10.8","Cell RNA - A-431 [nTPM]":"1.3","Cell RNA - A549 [nTPM]":"2.0","Cell RNA - AF22 [nTPM]":"7.6","Cell RNA - AN3-CA [nTPM]":"1.3","Cell RNA - ASC diff [nTPM]":"10.9","Cell RNA - ASC TERT1 [nTPM]":"14.9","Cell RNA - BEWO [nTPM]":"3.3","Cell RNA - BJ [nTPM]":"5.8","Cell RNA - BJ hTERT+ [nTPM]":"4.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.6","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"10.9","Cell RNA - GAMG [nTPM]":"14.7","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"3.3","Cell RNA - HBEC3-KT [nTPM]":"2.0","Cell RNA - HBF TERT88 [nTPM]":"8.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"2.8","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"1.0","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"2.4","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"8.7","Cell RNA - hTCEpi [nTPM]":"6.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.6","Cell RNA - hTERT-HME1 [nTPM]":"1.1","Cell RNA - hTERT-RPE1 [nTPM]":"6.6","Cell RNA - HUVEC TERT2 [nTPM]":"4.0","Cell RNA - JURKAT [nTPM]":"3.3","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"19.3","Cell RNA - LHCN-M2 [nTPM]":"19.7","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"1.0","Cell RNA - NTERA-2 [nTPM]":"1.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"5.7","Cell RNA - RH-30 [nTPM]":"29.7","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"9.9","Cell RNA - SH-SY5Y [nTPM]":"17.1","Cell RNA - SiHa [nTPM]":"3.7","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"7.7","Cell RNA - SuSa [nTPM]":"5.5","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"20.0","Cell RNA - TIME [nTPM]":"8.9","Cell RNA - U-138 MG [nTPM]":"14.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"15.3","Cell RNA - U-266\/70 [nTPM]":"1.8","Cell RNA - U-266\/84 [nTPM]":"0.8","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"8.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"30.2","Blood RNA - basophil [nTPM]":"0.8","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.6","Brain RNA - basal ganglia [nTPM]":"7.1","Brain RNA - cerebellum [nTPM]":"5.8","Brain RNA - cerebral cortex [nTPM]":"3.6","Brain RNA - hippocampal formation [nTPM]":"2.7","Brain RNA - hypothalamus [nTPM]":"4.3","Brain RNA - medulla oblongata [nTPM]":"7.3","Brain RNA - midbrain [nTPM]":"5.6","Brain RNA - pons [nTPM]":"7.4","Brain RNA - spinal cord [nTPM]":"5.2","Brain RNA - thalamus [nTPM]":"5.2","Brain RNA - white matter [nTPM]":"10.8","Single Cell Type RNA - Adipocytes [nTPM]":"2.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"34.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"36.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.4","Single Cell Type RNA - Endothelial cells [nTPM]":"3.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"2.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.9","Single Cell Type RNA - Late spermatids [nTPM]":"55.3","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"3.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.4","Single Cell Type RNA - Spermatocytes [nTPM]":"24.4","Single Cell Type RNA - Spermatogonia [nTPM]":"5.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"1.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"C1QBP","Gene synonym":["gC1Q-R","gC1qR","HABP1","p32","SF2p32"],"Ensembl":"ENSG00000108561","Gene description":"Complement C1q binding protein","Uniprot":["Q07021"],"Chromosome":"17","Position":"5432777-5448830","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins","Transporters"],"Biological process":["Adaptive immunity","Apoptosis","Complement pathway","Host-virus interaction","Immunity","Innate immunity","mRNA processing","mRNA splicing","Ribosome biogenesis","Transcription","Transcription regulation"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026483"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Mitochondria"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"410000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"HPA026483":"AB_1847108"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.80e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-1"},"Tissue RNA - adipose tissue [nTPM]":"79.3","Tissue RNA - adrenal gland [nTPM]":"135.4","Tissue RNA - amygdala [nTPM]":"85.5","Tissue RNA - appendix [nTPM]":"84.1","Tissue RNA - basal ganglia [nTPM]":"85.7","Tissue RNA - bone marrow [nTPM]":"121.2","Tissue RNA - breast [nTPM]":"108.7","Tissue RNA - cerebellum [nTPM]":"91.5","Tissue RNA - cerebral cortex [nTPM]":"118.3","Tissue RNA - cervix [nTPM]":"58.4","Tissue RNA - choroid plexus [nTPM]":"119.6","Tissue RNA - colon [nTPM]":"140.3","Tissue RNA - duodenum [nTPM]":"95.9","Tissue RNA - endometrium 1 [nTPM]":"66.4","Tissue RNA - epididymis [nTPM]":"68.3","Tissue RNA - esophagus [nTPM]":"138.6","Tissue RNA - fallopian tube [nTPM]":"74.5","Tissue RNA - gallbladder [nTPM]":"48.7","Tissue RNA - heart muscle [nTPM]":"126.3","Tissue RNA - hippocampal formation [nTPM]":"89.5","Tissue RNA - hypothalamus [nTPM]":"94.3","Tissue RNA - kidney [nTPM]":"136.4","Tissue RNA - liver [nTPM]":"134.5","Tissue RNA - lung [nTPM]":"54.7","Tissue RNA - lymph node [nTPM]":"115.7","Tissue RNA - medulla oblongata [nTPM]":"89.6","Tissue RNA - midbrain [nTPM]":"92.3","Tissue RNA - ovary [nTPM]":"52.7","Tissue RNA - pancreas [nTPM]":"72.9","Tissue RNA - parathyroid gland [nTPM]":"127.7","Tissue RNA - pituitary gland [nTPM]":"81.3","Tissue RNA - placenta [nTPM]":"75.8","Tissue RNA - pons [nTPM]":"93.2","Tissue RNA - prostate [nTPM]":"63.9","Tissue RNA - rectum [nTPM]":"141.6","Tissue RNA - retina [nTPM]":"86.7","Tissue RNA - salivary gland [nTPM]":"66.2","Tissue RNA - seminal vesicle [nTPM]":"73.1","Tissue RNA - skeletal muscle [nTPM]":"174.2","Tissue RNA - skin 1 [nTPM]":"81.3","Tissue RNA - small intestine [nTPM]":"78.4","Tissue RNA - smooth muscle [nTPM]":"80.9","Tissue RNA - spinal cord [nTPM]":"93.1","Tissue RNA - spleen [nTPM]":"73.5","Tissue RNA - stomach 1 [nTPM]":"74.3","Tissue RNA - testis [nTPM]":"62.5","Tissue RNA - thalamus [nTPM]":"90.7","Tissue RNA - thymus [nTPM]":"98.5","Tissue RNA - thyroid gland [nTPM]":"65.1","Tissue RNA - tongue [nTPM]":"160.1","Tissue RNA - tonsil [nTPM]":"135.6","Tissue RNA - urinary bladder [nTPM]":"108.4","Tissue RNA - vagina [nTPM]":"73.9","Tissue RNA - white matter [nTPM]":"97.3","Cell RNA - A-431 [nTPM]":"443.8","Cell RNA - A549 [nTPM]":"671.0","Cell RNA - AF22 [nTPM]":"233.0","Cell RNA - AN3-CA [nTPM]":"378.0","Cell RNA - ASC diff [nTPM]":"169.8","Cell RNA - ASC TERT1 [nTPM]":"207.7","Cell RNA - BEWO [nTPM]":"313.7","Cell RNA - BJ [nTPM]":"330.4","Cell RNA - BJ hTERT+ [nTPM]":"268.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"751.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"458.8","Cell RNA - CACO-2 [nTPM]":"646.8","Cell RNA - CAPAN-2 [nTPM]":"143.7","Cell RNA - Daudi [nTPM]":"941.8","Cell RNA - EFO-21 [nTPM]":"317.8","Cell RNA - fHDF\/TERT166 [nTPM]":"251.3","Cell RNA - GAMG [nTPM]":"271.3","Cell RNA - HaCaT [nTPM]":"385.8","Cell RNA - HAP1 [nTPM]":"756.7","Cell RNA - HBEC3-KT [nTPM]":"448.9","Cell RNA - HBF TERT88 [nTPM]":"689.8","Cell RNA - HDLM-2 [nTPM]":"216.6","Cell RNA - HEK 293 [nTPM]":"1300.5","Cell RNA - HEL [nTPM]":"433.9","Cell RNA - HeLa [nTPM]":"312.4","Cell RNA - Hep G2 [nTPM]":"762.2","Cell RNA - HHSteC [nTPM]":"269.9","Cell RNA - HL-60 [nTPM]":"535.6","Cell RNA - HMC-1 [nTPM]":"331.0","Cell RNA - HSkMC [nTPM]":"231.4","Cell RNA - hTCEpi [nTPM]":"404.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"414.6","Cell RNA - hTERT-HME1 [nTPM]":"593.1","Cell RNA - hTERT-RPE1 [nTPM]":"181.1","Cell RNA - HUVEC TERT2 [nTPM]":"390.0","Cell RNA - JURKAT [nTPM]":"548.2","Cell RNA - K-562 [nTPM]":"526.1","Cell RNA - Karpas-707 [nTPM]":"234.4","Cell RNA - LHCN-M2 [nTPM]":"296.1","Cell RNA - MCF7 [nTPM]":"308.6","Cell RNA - MOLT-4 [nTPM]":"766.4","Cell RNA - NB-4 [nTPM]":"385.6","Cell RNA - NTERA-2 [nTPM]":"525.9","Cell RNA - OE19 [nTPM]":"497.2","Cell RNA - PC-3 [nTPM]":"396.7","Cell RNA - REH [nTPM]":"601.2","Cell RNA - RH-30 [nTPM]":"329.1","Cell RNA - RPMI-8226 [nTPM]":"515.0","Cell RNA - RPTEC TERT1 [nTPM]":"440.5","Cell RNA - RT4 [nTPM]":"328.7","Cell RNA - SCLC-21H [nTPM]":"186.0","Cell RNA - SH-SY5Y [nTPM]":"348.0","Cell RNA - SiHa [nTPM]":"271.4","Cell RNA - SK-BR-3 [nTPM]":"344.4","Cell RNA - SK-MEL-30 [nTPM]":"483.6","Cell RNA - SuSa [nTPM]":"232.1","Cell RNA - T-47d [nTPM]":"218.1","Cell RNA - THP-1 [nTPM]":"267.1","Cell RNA - TIME [nTPM]":"231.1","Cell RNA - U-138 MG [nTPM]":"240.1","Cell RNA - U-2 OS [nTPM]":"219.7","Cell RNA - U-2197 [nTPM]":"275.9","Cell RNA - U-251 MG [nTPM]":"729.9","Cell RNA - U-266\/70 [nTPM]":"122.0","Cell RNA - U-266\/84 [nTPM]":"201.2","Cell RNA - U-698 [nTPM]":"415.0","Cell RNA - U-87 MG [nTPM]":"229.3","Cell RNA - U-937 [nTPM]":"506.2","Cell RNA - WM-115 [nTPM]":"376.8","Blood RNA - basophil [nTPM]":"68.1","Blood RNA - classical monocyte [nTPM]":"197.6","Blood RNA - eosinophil [nTPM]":"49.9","Blood RNA - gdT-cell [nTPM]":"217.1","Blood RNA - intermediate monocyte [nTPM]":"212.0","Blood RNA - MAIT T-cell [nTPM]":"283.5","Blood RNA - memory B-cell [nTPM]":"330.1","Blood RNA - memory CD4 T-cell [nTPM]":"239.0","Blood RNA - memory CD8 T-cell [nTPM]":"215.4","Blood RNA - myeloid DC [nTPM]":"389.5","Blood RNA - naive B-cell [nTPM]":"289.8","Blood RNA - naive CD4 T-cell [nTPM]":"289.7","Blood RNA - naive CD8 T-cell [nTPM]":"245.7","Blood RNA - neutrophil [nTPM]":"15.5","Blood RNA - NK-cell [nTPM]":"240.7","Blood RNA - non-classical monocyte [nTPM]":"166.4","Blood RNA - plasmacytoid DC [nTPM]":"325.4","Blood RNA - T-reg [nTPM]":"203.6","Blood RNA - total PBMC [nTPM]":"432.6","Brain RNA - amygdala [nTPM]":"85.5","Brain RNA - basal ganglia [nTPM]":"85.7","Brain RNA - cerebellum [nTPM]":"91.5","Brain RNA - cerebral cortex [nTPM]":"118.3","Brain RNA - hippocampal formation [nTPM]":"89.5","Brain RNA - hypothalamus [nTPM]":"94.3","Brain RNA - medulla oblongata [nTPM]":"89.6","Brain RNA - midbrain [nTPM]":"92.3","Brain RNA - pons [nTPM]":"93.2","Brain RNA - spinal cord [nTPM]":"93.1","Brain RNA - thalamus [nTPM]":"90.7","Brain RNA - white matter [nTPM]":"97.3","Single Cell Type RNA - Adipocytes [nTPM]":"101.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"30.5","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"153.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"243.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"229.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"283.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"165.0","Single Cell Type RNA - Bipolar cells [nTPM]":"70.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"157.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"209.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"84.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"102.9","Single Cell Type RNA - Club cells [nTPM]":"107.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"82.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"323.8","Single Cell Type RNA - dendritic cells [nTPM]":"115.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"105.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"313.1","Single Cell Type RNA - Ductal cells [nTPM]":"248.0","Single Cell Type RNA - Early spermatids [nTPM]":"75.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"106.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"149.9","Single Cell Type RNA - Endothelial cells [nTPM]":"108.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"79.2","Single Cell Type RNA - Erythroid cells [nTPM]":"183.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"205.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"457.9","Single Cell Type RNA - Fibroblasts [nTPM]":"101.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"94.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"85.9","Single Cell Type RNA - granulocytes [nTPM]":"62.2","Single Cell Type RNA - Granulosa cells [nTPM]":"131.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"75.3","Single Cell Type RNA - Hepatocytes [nTPM]":"128.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"202.7","Single Cell Type RNA - Horizontal cells [nTPM]":"60.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"190.2","Single Cell Type RNA - Ionocytes [nTPM]":"154.6","Single Cell Type RNA - Kupffer cells [nTPM]":"85.3","Single Cell Type RNA - Langerhans cells [nTPM]":"129.8","Single Cell Type RNA - Late spermatids [nTPM]":"89.5","Single Cell Type RNA - Leydig cells [nTPM]":"119.6","Single Cell Type RNA - Macrophages [nTPM]":"101.8","Single Cell Type RNA - Melanocytes [nTPM]":"156.5","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"170.3","Single Cell Type RNA - Muller glia cells [nTPM]":"105.2","Single Cell Type RNA - NK-cells [nTPM]":"93.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"199.3","Single Cell Type RNA - Paneth cells [nTPM]":"128.5","Single Cell Type RNA - Peritubular cells [nTPM]":"98.6","Single Cell Type RNA - Plasma cells [nTPM]":"197.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"255.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"78.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"444.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"65.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"79.9","Single Cell Type RNA - Sertoli cells [nTPM]":"85.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"101.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"189.1","Single Cell Type RNA - Spermatocytes [nTPM]":"79.3","Single Cell Type RNA - Spermatogonia [nTPM]":"237.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"284.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"255.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"179.0","Single Cell Type RNA - T-cells [nTPM]":"105.5","Single Cell Type RNA - Theca cells [nTPM]":"354.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"364.0","Single Cell Type RNA - Urothelial cells [nTPM]":"253.8"},{"Gene":"C2","Gene synonym":[],"Ensembl":"ENSG00000166278","Gene description":"Complement C2","Uniprot":["P06681"],"Chromosome":"6","Position":"31897785-31945672","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Complement pathway","Immunity","Innate immunity"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Age-related macular degeneration","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"liver":"477.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Alveolar cells type 2":"142.4","Hepatocytes":"380.3","Hofbauer cells":"282.7","Kupffer cells":"99.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"liver cancer":"100.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"intermediate monocyte":"21.1","non-classical monocyte":"25.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"35","RNA blood lineage specific nTPM":{"monocytes":"25.9"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Karpas-707":"284.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016775"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"34000000000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB016775":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.64e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Tissue RNA - adipose tissue [nTPM]":"42.6","Tissue RNA - adrenal gland [nTPM]":"12.1","Tissue RNA - amygdala [nTPM]":"0.8","Tissue RNA - appendix [nTPM]":"27.6","Tissue RNA - basal ganglia [nTPM]":"1.0","Tissue RNA - bone marrow [nTPM]":"3.2","Tissue RNA - breast [nTPM]":"11.7","Tissue RNA - cerebellum [nTPM]":"0.9","Tissue RNA - cerebral cortex [nTPM]":"1.4","Tissue RNA - cervix [nTPM]":"8.1","Tissue RNA - choroid plexus [nTPM]":"1.7","Tissue RNA - colon [nTPM]":"14.3","Tissue RNA - duodenum [nTPM]":"16.7","Tissue RNA - endometrium 1 [nTPM]":"7.0","Tissue RNA - epididymis [nTPM]":"1.3","Tissue RNA - esophagus [nTPM]":"7.6","Tissue RNA - fallopian tube [nTPM]":"12.0","Tissue RNA - gallbladder [nTPM]":"23.0","Tissue RNA - heart muscle [nTPM]":"8.5","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"23.2","Tissue RNA - liver [nTPM]":"477.9","Tissue RNA - lung [nTPM]":"80.0","Tissue RNA - lymph node [nTPM]":"27.8","Tissue RNA - medulla oblongata [nTPM]":"3.0","Tissue RNA - midbrain [nTPM]":"2.6","Tissue RNA - ovary [nTPM]":"5.3","Tissue RNA - pancreas [nTPM]":"1.9","Tissue RNA - parathyroid gland [nTPM]":"0.9","Tissue RNA - pituitary gland [nTPM]":"3.8","Tissue RNA - placenta [nTPM]":"48.4","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"5.4","Tissue RNA - rectum [nTPM]":"13.0","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"9.1","Tissue RNA - seminal vesicle [nTPM]":"0.9","Tissue RNA - skeletal muscle [nTPM]":"2.1","Tissue RNA - skin 1 [nTPM]":"5.8","Tissue RNA - small intestine [nTPM]":"30.2","Tissue RNA - smooth muscle [nTPM]":"23.6","Tissue RNA - spinal cord [nTPM]":"2.1","Tissue RNA - spleen [nTPM]":"46.3","Tissue RNA - stomach 1 [nTPM]":"12.0","Tissue RNA - testis [nTPM]":"4.1","Tissue RNA - thalamus [nTPM]":"3.7","Tissue RNA - thymus [nTPM]":"5.5","Tissue RNA - thyroid gland [nTPM]":"3.3","Tissue RNA - tongue [nTPM]":"2.7","Tissue RNA - tonsil [nTPM]":"12.5","Tissue RNA - urinary bladder [nTPM]":"23.6","Tissue RNA - vagina [nTPM]":"5.3","Tissue RNA - white matter [nTPM]":"2.1","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.6","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"6.8","Cell RNA - BJ [nTPM]":"0.5","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"0.6","Cell RNA - EFO-21 [nTPM]":"3.5","Cell RNA - fHDF\/TERT166 [nTPM]":"1.0","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"52.8","Cell RNA - HHSteC [nTPM]":"1.1","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.7","Cell RNA - HSkMC [nTPM]":"2.7","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.6","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.5","Cell RNA - Karpas-707 [nTPM]":"284.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"16.5","Cell RNA - RPMI-8226 [nTPM]":"3.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"2.6","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"9.5","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"31.6","Cell RNA - U-698 [nTPM]":"2.7","Cell RNA - U-87 MG [nTPM]":"0.8","Cell RNA - U-937 [nTPM]":"0.9","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"5.6","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"21.1","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"25.9","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"2.2","Brain RNA - amygdala [nTPM]":"0.8","Brain RNA - basal ganglia [nTPM]":"1.0","Brain RNA - cerebellum [nTPM]":"0.9","Brain RNA - cerebral cortex [nTPM]":"1.4","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"3.0","Brain RNA - midbrain [nTPM]":"2.6","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"2.1","Brain RNA - thalamus [nTPM]":"3.7","Brain RNA - white matter [nTPM]":"2.1","Single Cell Type RNA - Adipocytes [nTPM]":"2.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"142.4","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"1.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"11.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.7","Single Cell Type RNA - Endothelial cells [nTPM]":"1.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"10.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.7","Single Cell Type RNA - Fibroblasts [nTPM]":"19.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.3","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.0","Single Cell Type RNA - Hepatocytes [nTPM]":"380.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"282.7","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"99.3","Single Cell Type RNA - Langerhans cells [nTPM]":"5.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"6.8","Single Cell Type RNA - Macrophages [nTPM]":"32.6","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"7.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.5","Single Cell Type RNA - Paneth cells [nTPM]":"33.1","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"55.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"35.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"1.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.0","Single Cell Type RNA - T-cells [nTPM]":"2.0","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.8","Single Cell Type RNA - Urothelial cells [nTPM]":"4.5"},{"Gene":"C6","Gene synonym":[],"Ensembl":"ENSG00000039537","Gene description":"Complement C6","Uniprot":["P13671"],"Chromosome":"5","Position":"41142116-41261438","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted secreted proteins","Transporters"],"Biological process":["Complement pathway","Cytolysis","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"liver":"665.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"127.2","Hepatocytes":"376.9","Late spermatids":"54.8","Leydig cells":"120.2","Respiratory ciliated cells":"58.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"liver cancer":"49.0","pancreatic cancer":"12.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"13","RNA cell line specific nTPM":{"ASC diff":"4.5","ASC TERT1":"6.2","HSkMC":"16.8"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043823","CAB069427"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":45000000000,"Blood concentration - Conc. blood MS [pg\/L]":"9200000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB069427":"AB_1614336","HPA043823":"AB_10960262"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.31e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"},"Tissue RNA - adipose tissue [nTPM]":"12.8","Tissue RNA - adrenal gland [nTPM]":"1.1","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"5.4","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.8","Tissue RNA - choroid plexus [nTPM]":"1.6","Tissue RNA - colon [nTPM]":"0.8","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"43.9","Tissue RNA - gallbladder [nTPM]":"12.0","Tissue RNA - heart muscle [nTPM]":"57.1","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"4.4","Tissue RNA - liver [nTPM]":"665.9","Tissue RNA - lung [nTPM]":"3.2","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"1.7","Tissue RNA - ovary [nTPM]":"6.2","Tissue RNA - pancreas [nTPM]":"42.7","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.7","Tissue RNA - placenta [nTPM]":"2.8","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.9","Tissue RNA - rectum [nTPM]":"0.6","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.9","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"0.6","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"1.4","Tissue RNA - smooth muscle [nTPM]":"0.9","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"2.2","Tissue RNA - testis [nTPM]":"4.2","Tissue RNA - thalamus [nTPM]":"0.8","Tissue RNA - thymus [nTPM]":"0.6","Tissue RNA - thyroid gland [nTPM]":"2.0","Tissue RNA - tongue [nTPM]":"0.7","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"0.9","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"4.5","Cell RNA - ASC TERT1 [nTPM]":"6.2","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.6","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"16.8","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"1.7","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.8","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"20.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"127.2","Single Cell Type RNA - Club cells [nTPM]":"7.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"9.3","Single Cell Type RNA - Early spermatids [nTPM]":"11.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"37.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.8","Single Cell Type RNA - Endothelial cells [nTPM]":"0.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"8.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"6.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"376.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"9.7","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"54.8","Single Cell Type RNA - Leydig cells [nTPM]":"120.2","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"1.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"58.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"C8A","Gene synonym":[],"Ensembl":"ENSG00000157131","Gene description":"Complement C8 alpha chain","Uniprot":["P07357"],"Chromosome":"1","Position":"56854797-56918223","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted secreted proteins","Transporters"],"Biological process":["Complement alternate pathway","Complement pathway","Cytolysis","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"195","RNA tissue specific nTPM":{"liver":"635.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"36","RNA single cell type specific nTPM":{"Hepatocytes":"296.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"279","RNA cancer specific FPKM":{"liver cancer":"85.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Hep G2":"1.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6400000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"1.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"3.2","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"635.7","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.7","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"1.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"296.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"8.2","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"CAD","Gene synonym":["GATD4"],"Ensembl":"ENSG00000084774","Gene description":"Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase","Uniprot":["P27708"],"Chromosome":"2","Position":"27217369-27243943","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Pyrimidine biosynthesis"],"Molecular function":["Allosteric enzyme","Hydrolase","Ligase","Multifunctional enzyme","Transferase"],"Disease involvement":["Cancer-related genes","Congenital disorder of glycosylation","Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB007781","HPA065158","HPA069341"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"260000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB007781":"AB_562057","HPA065158":null,"HPA069341":"AB_2686125"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.72e-11"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.82e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-3"},"Tissue RNA - adipose tissue [nTPM]":"15.0","Tissue RNA - adrenal gland [nTPM]":"13.5","Tissue RNA - amygdala [nTPM]":"12.7","Tissue RNA - appendix [nTPM]":"12.4","Tissue RNA - basal ganglia [nTPM]":"14.1","Tissue RNA - bone marrow [nTPM]":"9.0","Tissue RNA - breast [nTPM]":"14.9","Tissue RNA - cerebellum [nTPM]":"12.7","Tissue RNA - cerebral cortex [nTPM]":"15.5","Tissue RNA - cervix [nTPM]":"19.8","Tissue RNA - choroid plexus [nTPM]":"12.2","Tissue RNA - colon [nTPM]":"16.5","Tissue RNA - duodenum [nTPM]":"8.5","Tissue RNA - endometrium 1 [nTPM]":"23.8","Tissue RNA - epididymis [nTPM]":"9.9","Tissue RNA - esophagus [nTPM]":"19.2","Tissue RNA - fallopian tube [nTPM]":"19.3","Tissue RNA - gallbladder [nTPM]":"7.7","Tissue RNA - heart muscle [nTPM]":"11.6","Tissue RNA - hippocampal formation [nTPM]":"12.3","Tissue RNA - hypothalamus [nTPM]":"12.8","Tissue RNA - kidney [nTPM]":"18.0","Tissue RNA - liver [nTPM]":"27.8","Tissue RNA - lung [nTPM]":"12.3","Tissue RNA - lymph node [nTPM]":"14.9","Tissue RNA - medulla oblongata [nTPM]":"13.8","Tissue RNA - midbrain [nTPM]":"13.5","Tissue RNA - ovary [nTPM]":"22.3","Tissue RNA - pancreas [nTPM]":"22.3","Tissue RNA - parathyroid gland [nTPM]":"5.9","Tissue RNA - pituitary gland [nTPM]":"18.7","Tissue RNA - placenta [nTPM]":"7.5","Tissue RNA - pons [nTPM]":"14.5","Tissue RNA - prostate [nTPM]":"15.2","Tissue RNA - rectum [nTPM]":"7.8","Tissue RNA - retina [nTPM]":"5.0","Tissue RNA - salivary gland [nTPM]":"12.3","Tissue RNA - seminal vesicle [nTPM]":"8.8","Tissue RNA - skeletal muscle [nTPM]":"10.3","Tissue RNA - skin 1 [nTPM]":"18.7","Tissue RNA - small intestine [nTPM]":"16.1","Tissue RNA - smooth muscle [nTPM]":"11.9","Tissue RNA - spinal cord [nTPM]":"12.7","Tissue RNA - spleen [nTPM]":"20.1","Tissue RNA - stomach 1 [nTPM]":"14.0","Tissue RNA - testis [nTPM]":"22.2","Tissue RNA - thalamus [nTPM]":"14.2","Tissue RNA - thymus [nTPM]":"11.6","Tissue RNA - thyroid gland [nTPM]":"15.8","Tissue RNA - tongue [nTPM]":"5.9","Tissue RNA - tonsil [nTPM]":"10.5","Tissue RNA - urinary bladder [nTPM]":"16.9","Tissue RNA - vagina [nTPM]":"15.8","Tissue RNA - white matter [nTPM]":"15.2","Cell RNA - A-431 [nTPM]":"75.2","Cell RNA - A549 [nTPM]":"66.4","Cell RNA - AF22 [nTPM]":"28.9","Cell RNA - AN3-CA [nTPM]":"58.4","Cell RNA - ASC diff [nTPM]":"46.1","Cell RNA - ASC TERT1 [nTPM]":"37.6","Cell RNA - BEWO [nTPM]":"22.9","Cell RNA - BJ [nTPM]":"31.0","Cell RNA - BJ hTERT+ [nTPM]":"21.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"38.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"27.0","Cell RNA - CACO-2 [nTPM]":"75.7","Cell RNA - CAPAN-2 [nTPM]":"29.2","Cell RNA - Daudi [nTPM]":"66.4","Cell RNA - EFO-21 [nTPM]":"27.4","Cell RNA - fHDF\/TERT166 [nTPM]":"28.5","Cell RNA - GAMG [nTPM]":"29.6","Cell RNA - HaCaT [nTPM]":"41.4","Cell RNA - HAP1 [nTPM]":"85.7","Cell RNA - HBEC3-KT [nTPM]":"41.1","Cell RNA - HBF TERT88 [nTPM]":"28.5","Cell RNA - HDLM-2 [nTPM]":"43.8","Cell RNA - HEK 293 [nTPM]":"69.2","Cell RNA - HEL [nTPM]":"95.2","Cell RNA - HeLa [nTPM]":"55.0","Cell RNA - Hep G2 [nTPM]":"40.0","Cell RNA - HHSteC [nTPM]":"23.0","Cell RNA - HL-60 [nTPM]":"75.7","Cell RNA - HMC-1 [nTPM]":"46.2","Cell RNA - HSkMC [nTPM]":"28.8","Cell RNA - hTCEpi [nTPM]":"33.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"55.7","Cell RNA - hTERT-HME1 [nTPM]":"63.0","Cell RNA - hTERT-RPE1 [nTPM]":"17.8","Cell RNA - HUVEC TERT2 [nTPM]":"41.6","Cell RNA - JURKAT [nTPM]":"60.6","Cell RNA - K-562 [nTPM]":"68.3","Cell RNA - Karpas-707 [nTPM]":"36.0","Cell RNA - LHCN-M2 [nTPM]":"34.2","Cell RNA - MCF7 [nTPM]":"74.8","Cell RNA - MOLT-4 [nTPM]":"48.7","Cell RNA - NB-4 [nTPM]":"112.0","Cell RNA - NTERA-2 [nTPM]":"69.7","Cell RNA - OE19 [nTPM]":"31.3","Cell RNA - PC-3 [nTPM]":"49.7","Cell RNA - REH [nTPM]":"84.0","Cell RNA - RH-30 [nTPM]":"86.5","Cell RNA - RPMI-8226 [nTPM]":"69.5","Cell RNA - RPTEC TERT1 [nTPM]":"28.6","Cell RNA - RT4 [nTPM]":"37.6","Cell RNA - SCLC-21H [nTPM]":"57.9","Cell RNA - SH-SY5Y [nTPM]":"29.1","Cell RNA - SiHa [nTPM]":"43.3","Cell RNA - SK-BR-3 [nTPM]":"30.5","Cell RNA - SK-MEL-30 [nTPM]":"37.4","Cell RNA - SuSa [nTPM]":"21.3","Cell RNA - T-47d [nTPM]":"23.9","Cell RNA - THP-1 [nTPM]":"31.3","Cell RNA - TIME [nTPM]":"37.7","Cell RNA - U-138 MG [nTPM]":"57.7","Cell RNA - U-2 OS [nTPM]":"47.5","Cell RNA - U-2197 [nTPM]":"45.5","Cell RNA - U-251 MG [nTPM]":"63.5","Cell RNA - U-266\/70 [nTPM]":"74.0","Cell RNA - U-266\/84 [nTPM]":"51.8","Cell RNA - U-698 [nTPM]":"135.2","Cell RNA - U-87 MG [nTPM]":"23.3","Cell RNA - U-937 [nTPM]":"71.7","Cell RNA - WM-115 [nTPM]":"51.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.8","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"3.1","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"2.5","Blood RNA - memory B-cell [nTPM]":"3.4","Blood RNA - memory CD4 T-cell [nTPM]":"4.4","Blood RNA - memory CD8 T-cell [nTPM]":"5.2","Blood RNA - myeloid DC [nTPM]":"1.9","Blood RNA - naive B-cell [nTPM]":"3.1","Blood RNA - naive CD4 T-cell [nTPM]":"2.8","Blood RNA - naive CD8 T-cell [nTPM]":"2.8","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"2.7","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"3.4","Blood RNA - T-reg [nTPM]":"5.9","Blood RNA - total PBMC [nTPM]":"2.0","Brain RNA - amygdala [nTPM]":"12.7","Brain RNA - basal ganglia [nTPM]":"14.1","Brain RNA - cerebellum [nTPM]":"12.7","Brain RNA - cerebral cortex [nTPM]":"15.5","Brain RNA - hippocampal formation [nTPM]":"12.3","Brain RNA - hypothalamus [nTPM]":"12.8","Brain RNA - medulla oblongata [nTPM]":"13.8","Brain RNA - midbrain [nTPM]":"13.5","Brain RNA - pons [nTPM]":"14.5","Brain RNA - spinal cord [nTPM]":"12.7","Brain RNA - thalamus [nTPM]":"14.2","Brain RNA - white matter [nTPM]":"15.2","Single Cell Type RNA - Adipocytes [nTPM]":"4.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.9","Single Cell Type RNA - Astrocytes [nTPM]":"12.7","Single Cell Type RNA - B-cells [nTPM]":"5.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"10.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"4.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.9","Single Cell Type RNA - dendritic cells [nTPM]":"3.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.9","Single Cell Type RNA - Endothelial cells [nTPM]":"5.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.6","Single Cell Type RNA - Erythroid cells [nTPM]":"9.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.6","Single Cell Type RNA - Fibroblasts [nTPM]":"7.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.3","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"16.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"6.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.7","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.9","Single Cell Type RNA - Late spermatids [nTPM]":"1.9","Single Cell Type RNA - Leydig cells [nTPM]":"6.2","Single Cell Type RNA - Macrophages [nTPM]":"3.6","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"4.7","Single Cell Type RNA - Muller glia cells [nTPM]":"4.1","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.9","Single Cell Type RNA - Paneth cells [nTPM]":"1.9","Single Cell Type RNA - Peritubular cells [nTPM]":"9.8","Single Cell Type RNA - Plasma cells [nTPM]":"7.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.2","Single Cell Type RNA - Spermatocytes [nTPM]":"5.6","Single Cell Type RNA - Spermatogonia [nTPM]":"12.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.2","Single Cell Type RNA - T-cells [nTPM]":"5.1","Single Cell Type RNA - Theca cells [nTPM]":"9.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.5","Single Cell Type RNA - Urothelial cells [nTPM]":"2.2"},{"Gene":"CAMK2A","Gene synonym":["CAMKA","CaMKII\u00c3\u017d\u00c2\u00b1","CaMKIINalpha","KIAA0968"],"Ensembl":"ENSG00000070808","Gene description":"Calcium\/calmodulin dependent protein kinase II alpha","Uniprot":["Q9UQM7"],"Chromosome":"5","Position":"150219491-150290291","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Calmodulin-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"662.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"245.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"13","RNA cancer specific FPKM":{"glioma":"6.0"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"662.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"1.3","SCLC-21H":"3.0","SuSa":"1.4","U-87 MG":"3.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebral cortex":"1071.1"},"Antibody":["CAB004330","HPA051783","HPA051785","HPA053973"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cell Junctions","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"66000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cell Junctions","Cytosol"],"Antibody RRID":{"CAB004330":"AB_626788","HPA051783":"AB_2681608","HPA051785":"AB_2681609","HPA053973":"AB_2682328"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.19e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.9","Tissue RNA - amygdala [nTPM]":"161.7","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"230.9","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"662.9","Tissue RNA - cervix [nTPM]":"1.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.0","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"2.8","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"1.3","Tissue RNA - fallopian tube [nTPM]":"1.5","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"4.8","Tissue RNA - hippocampal formation [nTPM]":"453.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.7","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.9","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"3.5","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.8","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"1.9","Tissue RNA - salivary gland [nTPM]":"0.7","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"95.0","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"2.4","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"34.7","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"2.0","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"99.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"1.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.9","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"3.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"1.4","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"3.9","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"161.7","Brain RNA - basal ganglia [nTPM]":"230.9","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"662.9","Brain RNA - hippocampal formation [nTPM]":"453.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"99.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"12.1","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"5.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"245.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"2.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"55.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CAMK2B","Gene synonym":["CAM2","CAMK2","CAMKB","CaMKII\u00c3\u017d\u00c2\u00b2"],"Ensembl":"ENSG00000058404","Gene description":"Calcium\/calmodulin dependent protein kinase II beta","Uniprot":["Q13554"],"Chromosome":"7","Position":"44217150-44334577","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Actin-binding","Calmodulin-binding","Developmental protein","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"248.8","skeletal muscle":"132.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Bipolar cells":"857.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"6.0","thyroid cancer":"6.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"SCLC-21H":"75.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB006849","HPA026307","HPA051783","HPA051785","HPA053973"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cell Junctions","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"600000","Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 47: Non-specific - Unknown function","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cell Junctions","Cytosol"],"Antibody RRID":{"CAB006849":null,"HPA026307":"AB_1845941","HPA051783":"AB_2681608","HPA051785":"AB_2681609","HPA053973":"AB_2682328"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"11.3","Tissue RNA - amygdala [nTPM]":"77.9","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"109.0","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"1.4","Tissue RNA - cerebellum [nTPM]":"113.0","Tissue RNA - cerebral cortex [nTPM]":"248.8","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.0","Tissue RNA - duodenum [nTPM]":"1.0","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"28.3","Tissue RNA - esophagus [nTPM]":"1.4","Tissue RNA - fallopian tube [nTPM]":"1.1","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"65.4","Tissue RNA - hippocampal formation [nTPM]":"197.6","Tissue RNA - hypothalamus [nTPM]":"12.6","Tissue RNA - kidney [nTPM]":"1.6","Tissue RNA - liver [nTPM]":"7.7","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"1.3","Tissue RNA - medulla oblongata [nTPM]":"4.4","Tissue RNA - midbrain [nTPM]":"11.9","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"3.8","Tissue RNA - parathyroid gland [nTPM]":"6.1","Tissue RNA - pituitary gland [nTPM]":"51.3","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"4.6","Tissue RNA - prostate [nTPM]":"3.2","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"21.4","Tissue RNA - salivary gland [nTPM]":"1.4","Tissue RNA - seminal vesicle [nTPM]":"1.6","Tissue RNA - skeletal muscle [nTPM]":"132.5","Tissue RNA - skin 1 [nTPM]":"1.2","Tissue RNA - small intestine [nTPM]":"0.9","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"3.2","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"2.3","Tissue RNA - testis [nTPM]":"2.1","Tissue RNA - thalamus [nTPM]":"25.9","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"20.3","Tissue RNA - tongue [nTPM]":"59.2","Tissue RNA - tonsil [nTPM]":"1.6","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"80.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"0.6","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"1.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.4","Cell RNA - HBEC3-KT [nTPM]":"1.4","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"2.0","Cell RNA - HEK 293 [nTPM]":"4.5","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.9","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.5","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"10.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"4.4","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"1.7","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"75.5","Cell RNA - SH-SY5Y [nTPM]":"4.0","Cell RNA - SiHa [nTPM]":"0.4","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"3.5","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.5","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"0.8","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"1.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"77.9","Brain RNA - basal ganglia [nTPM]":"109.0","Brain RNA - cerebellum [nTPM]":"113.0","Brain RNA - cerebral cortex [nTPM]":"248.8","Brain RNA - hippocampal formation [nTPM]":"197.6","Brain RNA - hypothalamus [nTPM]":"12.6","Brain RNA - medulla oblongata [nTPM]":"4.4","Brain RNA - midbrain [nTPM]":"11.9","Brain RNA - pons [nTPM]":"4.6","Brain RNA - spinal cord [nTPM]":"3.2","Brain RNA - thalamus [nTPM]":"25.9","Brain RNA - white matter [nTPM]":"80.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"67.3","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"857.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"88.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"1.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"40.7","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"111.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"2.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.6","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"15.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"4.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"60.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"90.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.5","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"2.9","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"23.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"53.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"7.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"6.6"},{"Gene":"CAMK2G","Gene synonym":["CAMKG"],"Ensembl":"ENSG00000148660","Gene description":"Calcium\/calmodulin dependent protein kinase II gamma","Uniprot":["Q13555"],"Chromosome":"10","Position":"73812501-73874591","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Calmodulin-binding","Developmental protein","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"154.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"410.7","Cytotrophoblasts":"163.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"133.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"PC-3":"154.8","SK-BR-3":"177.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040656","HPA051783","HPA051785","HPA053973"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cell Junctions","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"200000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cell Junctions","Cytosol"],"Antibody RRID":{"HPA040656":"AB_2677065","HPA051783":"AB_2681608","HPA051785":"AB_2681609","HPA053973":"AB_2682328"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-2"},"Tissue RNA - adipose tissue [nTPM]":"22.0","Tissue RNA - adrenal gland [nTPM]":"14.0","Tissue RNA - amygdala [nTPM]":"86.1","Tissue RNA - appendix [nTPM]":"17.0","Tissue RNA - basal ganglia [nTPM]":"92.6","Tissue RNA - bone marrow [nTPM]":"34.5","Tissue RNA - breast [nTPM]":"15.2","Tissue RNA - cerebellum [nTPM]":"79.9","Tissue RNA - cerebral cortex [nTPM]":"137.8","Tissue RNA - cervix [nTPM]":"24.1","Tissue RNA - choroid plexus [nTPM]":"44.1","Tissue RNA - colon [nTPM]":"101.1","Tissue RNA - duodenum [nTPM]":"34.2","Tissue RNA - endometrium 1 [nTPM]":"45.2","Tissue RNA - epididymis [nTPM]":"14.5","Tissue RNA - esophagus [nTPM]":"34.7","Tissue RNA - fallopian tube [nTPM]":"30.6","Tissue RNA - gallbladder [nTPM]":"17.8","Tissue RNA - heart muscle [nTPM]":"11.8","Tissue RNA - hippocampal formation [nTPM]":"91.3","Tissue RNA - hypothalamus [nTPM]":"79.0","Tissue RNA - kidney [nTPM]":"19.3","Tissue RNA - liver [nTPM]":"14.5","Tissue RNA - lung [nTPM]":"18.8","Tissue RNA - lymph node [nTPM]":"16.2","Tissue RNA - medulla oblongata [nTPM]":"96.1","Tissue RNA - midbrain [nTPM]":"96.5","Tissue RNA - ovary [nTPM]":"12.7","Tissue RNA - pancreas [nTPM]":"10.3","Tissue RNA - parathyroid gland [nTPM]":"12.3","Tissue RNA - pituitary gland [nTPM]":"14.1","Tissue RNA - placenta [nTPM]":"27.3","Tissue RNA - pons [nTPM]":"94.1","Tissue RNA - prostate [nTPM]":"31.1","Tissue RNA - rectum [nTPM]":"26.1","Tissue RNA - retina [nTPM]":"42.4","Tissue RNA - salivary gland [nTPM]":"22.9","Tissue RNA - seminal vesicle [nTPM]":"49.6","Tissue RNA - skeletal muscle [nTPM]":"154.3","Tissue RNA - skin 1 [nTPM]":"17.3","Tissue RNA - small intestine [nTPM]":"41.5","Tissue RNA - smooth muscle [nTPM]":"43.9","Tissue RNA - spinal cord [nTPM]":"91.4","Tissue RNA - spleen [nTPM]":"24.9","Tissue RNA - stomach 1 [nTPM]":"30.4","Tissue RNA - testis [nTPM]":"6.5","Tissue RNA - thalamus [nTPM]":"102.5","Tissue RNA - thymus [nTPM]":"15.7","Tissue RNA - thyroid gland [nTPM]":"13.6","Tissue RNA - tongue [nTPM]":"84.8","Tissue RNA - tonsil [nTPM]":"14.9","Tissue RNA - urinary bladder [nTPM]":"58.4","Tissue RNA - vagina [nTPM]":"25.8","Tissue RNA - white matter [nTPM]":"91.9","Cell RNA - A-431 [nTPM]":"35.7","Cell RNA - A549 [nTPM]":"24.6","Cell RNA - AF22 [nTPM]":"22.5","Cell RNA - AN3-CA [nTPM]":"43.9","Cell RNA - ASC diff [nTPM]":"16.7","Cell RNA - ASC TERT1 [nTPM]":"26.1","Cell RNA - BEWO [nTPM]":"26.3","Cell RNA - BJ [nTPM]":"25.8","Cell RNA - BJ hTERT+ [nTPM]":"41.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"31.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"26.1","Cell RNA - CACO-2 [nTPM]":"39.8","Cell RNA - CAPAN-2 [nTPM]":"37.2","Cell RNA - Daudi [nTPM]":"27.4","Cell RNA - EFO-21 [nTPM]":"25.7","Cell RNA - fHDF\/TERT166 [nTPM]":"32.4","Cell RNA - GAMG [nTPM]":"12.4","Cell RNA - HaCaT [nTPM]":"54.9","Cell RNA - HAP1 [nTPM]":"17.5","Cell RNA - HBEC3-KT [nTPM]":"20.5","Cell RNA - HBF TERT88 [nTPM]":"25.3","Cell RNA - HDLM-2 [nTPM]":"24.0","Cell RNA - HEK 293 [nTPM]":"22.2","Cell RNA - HEL [nTPM]":"18.2","Cell RNA - HeLa [nTPM]":"20.4","Cell RNA - Hep G2 [nTPM]":"17.8","Cell RNA - HHSteC [nTPM]":"8.1","Cell RNA - HL-60 [nTPM]":"24.7","Cell RNA - HMC-1 [nTPM]":"29.1","Cell RNA - HSkMC [nTPM]":"14.4","Cell RNA - hTCEpi [nTPM]":"17.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.5","Cell RNA - hTERT-HME1 [nTPM]":"22.1","Cell RNA - hTERT-RPE1 [nTPM]":"50.4","Cell RNA - HUVEC TERT2 [nTPM]":"28.3","Cell RNA - JURKAT [nTPM]":"32.5","Cell RNA - K-562 [nTPM]":"19.5","Cell RNA - Karpas-707 [nTPM]":"37.9","Cell RNA - LHCN-M2 [nTPM]":"19.0","Cell RNA - MCF7 [nTPM]":"25.2","Cell RNA - MOLT-4 [nTPM]":"41.7","Cell RNA - NB-4 [nTPM]":"37.5","Cell RNA - NTERA-2 [nTPM]":"16.5","Cell RNA - OE19 [nTPM]":"21.3","Cell RNA - PC-3 [nTPM]":"154.8","Cell RNA - REH [nTPM]":"36.5","Cell RNA - RH-30 [nTPM]":"25.3","Cell RNA - RPMI-8226 [nTPM]":"13.7","Cell RNA - RPTEC TERT1 [nTPM]":"17.2","Cell RNA - RT4 [nTPM]":"51.5","Cell RNA - SCLC-21H [nTPM]":"11.5","Cell RNA - SH-SY5Y [nTPM]":"28.4","Cell RNA - SiHa [nTPM]":"15.0","Cell RNA - SK-BR-3 [nTPM]":"177.4","Cell RNA - SK-MEL-30 [nTPM]":"11.9","Cell RNA - SuSa [nTPM]":"16.5","Cell RNA - T-47d [nTPM]":"33.2","Cell RNA - THP-1 [nTPM]":"15.0","Cell RNA - TIME [nTPM]":"36.7","Cell RNA - U-138 MG [nTPM]":"24.9","Cell RNA - U-2 OS [nTPM]":"40.0","Cell RNA - U-2197 [nTPM]":"13.4","Cell RNA - U-251 MG [nTPM]":"33.3","Cell RNA - U-266\/70 [nTPM]":"11.9","Cell RNA - U-266\/84 [nTPM]":"14.9","Cell RNA - U-698 [nTPM]":"24.8","Cell RNA - U-87 MG [nTPM]":"26.5","Cell RNA - U-937 [nTPM]":"69.2","Cell RNA - WM-115 [nTPM]":"8.8","Blood RNA - basophil [nTPM]":"31.0","Blood RNA - classical monocyte [nTPM]":"17.9","Blood RNA - eosinophil [nTPM]":"133.9","Blood RNA - gdT-cell [nTPM]":"23.1","Blood RNA - intermediate monocyte [nTPM]":"7.9","Blood RNA - MAIT T-cell [nTPM]":"28.5","Blood RNA - memory B-cell [nTPM]":"13.9","Blood RNA - memory CD4 T-cell [nTPM]":"26.3","Blood RNA - memory CD8 T-cell [nTPM]":"25.0","Blood RNA - myeloid DC [nTPM]":"23.0","Blood RNA - naive B-cell [nTPM]":"12.7","Blood RNA - naive CD4 T-cell [nTPM]":"24.5","Blood RNA - naive CD8 T-cell [nTPM]":"24.1","Blood RNA - neutrophil [nTPM]":"115.8","Blood RNA - NK-cell [nTPM]":"34.0","Blood RNA - non-classical monocyte [nTPM]":"15.1","Blood RNA - plasmacytoid DC [nTPM]":"7.9","Blood RNA - T-reg [nTPM]":"27.7","Blood RNA - total PBMC [nTPM]":"17.5","Brain RNA - amygdala [nTPM]":"86.1","Brain RNA - basal ganglia [nTPM]":"92.6","Brain RNA - cerebellum [nTPM]":"79.9","Brain RNA - cerebral cortex [nTPM]":"137.8","Brain RNA - hippocampal formation [nTPM]":"91.3","Brain RNA - hypothalamus [nTPM]":"79.0","Brain RNA - medulla oblongata [nTPM]":"96.1","Brain RNA - midbrain [nTPM]":"96.5","Brain RNA - pons [nTPM]":"94.1","Brain RNA - spinal cord [nTPM]":"91.4","Brain RNA - thalamus [nTPM]":"102.5","Brain RNA - white matter [nTPM]":"91.9","Single Cell Type RNA - Adipocytes [nTPM]":"19.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.7","Single Cell Type RNA - Astrocytes [nTPM]":"410.7","Single Cell Type RNA - B-cells [nTPM]":"22.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"63.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"15.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"100.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"163.6","Single Cell Type RNA - dendritic cells [nTPM]":"21.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"46.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"13.3","Single Cell Type RNA - Early spermatids [nTPM]":"2.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.4","Single Cell Type RNA - Endothelial cells [nTPM]":"20.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"23.9","Single Cell Type RNA - Erythroid cells [nTPM]":"13.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"107.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"45.2","Single Cell Type RNA - Fibroblasts [nTPM]":"12.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.5","Single Cell Type RNA - granulocytes [nTPM]":"16.5","Single Cell Type RNA - Granulosa cells [nTPM]":"20.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.4","Single Cell Type RNA - Hepatocytes [nTPM]":"9.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"27.2","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"89.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.8","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"18.9","Single Cell Type RNA - Langerhans cells [nTPM]":"16.3","Single Cell Type RNA - Late spermatids [nTPM]":"3.1","Single Cell Type RNA - Leydig cells [nTPM]":"12.8","Single Cell Type RNA - Macrophages [nTPM]":"15.8","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"43.1","Single Cell Type RNA - monocytes [nTPM]":"18.3","Single Cell Type RNA - Muller glia cells [nTPM]":"17.7","Single Cell Type RNA - NK-cells [nTPM]":"26.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"61.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.0","Single Cell Type RNA - Paneth cells [nTPM]":"65.5","Single Cell Type RNA - Peritubular cells [nTPM]":"18.8","Single Cell Type RNA - Plasma cells [nTPM]":"13.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"77.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"26.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"77.0","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"50.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"13.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"81.1","Single Cell Type RNA - T-cells [nTPM]":"30.3","Single Cell Type RNA - Theca cells [nTPM]":"5.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"32.1","Single Cell Type RNA - Urothelial cells [nTPM]":"13.7"},{"Gene":"CAMKMT","Gene synonym":["C2orf34","CLNMT"],"Ensembl":"ENSG00000143919","Gene description":"Calmodulin-lysine N-methyltransferase","Uniprot":["Q7Z624"],"Chromosome":"2","Position":"44361947-44772592","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"155.1","Excitatory neurons":"88.7","Inhibitory neurons":"93.7","Microglial cells":"114.3","Oligodendrocyte precursor cells":"121.2","Oligodendrocytes":"211.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067912"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA067912":"AB_2685922"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.10e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.2","Tissue RNA - adrenal gland [nTPM]":"5.3","Tissue RNA - amygdala [nTPM]":"15.9","Tissue RNA - appendix [nTPM]":"3.9","Tissue RNA - basal ganglia [nTPM]":"21.1","Tissue RNA - bone marrow [nTPM]":"10.2","Tissue RNA - breast [nTPM]":"5.3","Tissue RNA - cerebellum [nTPM]":"19.4","Tissue RNA - cerebral cortex [nTPM]":"21.1","Tissue RNA - cervix [nTPM]":"5.9","Tissue RNA - choroid plexus [nTPM]":"17.8","Tissue RNA - colon [nTPM]":"7.0","Tissue RNA - duodenum [nTPM]":"5.3","Tissue RNA - endometrium 1 [nTPM]":"4.1","Tissue RNA - epididymis [nTPM]":"6.5","Tissue RNA - esophagus [nTPM]":"6.1","Tissue RNA - fallopian tube [nTPM]":"4.9","Tissue RNA - gallbladder [nTPM]":"5.7","Tissue RNA - heart muscle [nTPM]":"5.0","Tissue RNA - hippocampal formation [nTPM]":"15.5","Tissue RNA - hypothalamus [nTPM]":"17.1","Tissue RNA - kidney [nTPM]":"7.5","Tissue RNA - liver [nTPM]":"4.8","Tissue RNA - lung [nTPM]":"3.9","Tissue RNA - lymph node [nTPM]":"5.4","Tissue RNA - medulla oblongata [nTPM]":"17.7","Tissue RNA - midbrain [nTPM]":"16.4","Tissue RNA - ovary [nTPM]":"3.9","Tissue RNA - pancreas [nTPM]":"9.8","Tissue RNA - parathyroid gland [nTPM]":"9.8","Tissue RNA - pituitary gland [nTPM]":"5.6","Tissue RNA - placenta [nTPM]":"3.3","Tissue RNA - pons [nTPM]":"17.3","Tissue RNA - prostate [nTPM]":"3.5","Tissue RNA - rectum [nTPM]":"6.8","Tissue RNA - retina [nTPM]":"8.5","Tissue RNA - salivary gland [nTPM]":"4.8","Tissue RNA - seminal vesicle [nTPM]":"3.9","Tissue RNA - skeletal muscle [nTPM]":"7.8","Tissue RNA - skin 1 [nTPM]":"5.8","Tissue RNA - small intestine [nTPM]":"5.7","Tissue RNA - smooth muscle [nTPM]":"3.9","Tissue RNA - spinal cord [nTPM]":"15.5","Tissue RNA - spleen [nTPM]":"3.7","Tissue RNA - stomach 1 [nTPM]":"5.8","Tissue RNA - testis [nTPM]":"13.2","Tissue RNA - thalamus [nTPM]":"17.9","Tissue RNA - thymus [nTPM]":"6.2","Tissue RNA - thyroid gland [nTPM]":"7.3","Tissue RNA - tongue [nTPM]":"3.3","Tissue RNA - tonsil [nTPM]":"5.4","Tissue RNA - urinary bladder [nTPM]":"4.5","Tissue RNA - vagina [nTPM]":"4.7","Tissue RNA - white matter [nTPM]":"20.4","Cell RNA - A-431 [nTPM]":"10.2","Cell RNA - A549 [nTPM]":"6.2","Cell RNA - AF22 [nTPM]":"7.4","Cell RNA - AN3-CA [nTPM]":"6.8","Cell RNA - ASC diff [nTPM]":"8.0","Cell RNA - ASC TERT1 [nTPM]":"8.1","Cell RNA - BEWO [nTPM]":"15.0","Cell RNA - BJ [nTPM]":"7.4","Cell RNA - BJ hTERT+ [nTPM]":"6.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.5","Cell RNA - CACO-2 [nTPM]":"11.9","Cell RNA - CAPAN-2 [nTPM]":"9.0","Cell RNA - Daudi [nTPM]":"9.6","Cell RNA - EFO-21 [nTPM]":"8.6","Cell RNA - fHDF\/TERT166 [nTPM]":"5.6","Cell RNA - GAMG [nTPM]":"5.3","Cell RNA - HaCaT [nTPM]":"8.3","Cell RNA - HAP1 [nTPM]":"10.6","Cell RNA - HBEC3-KT [nTPM]":"13.2","Cell RNA - HBF TERT88 [nTPM]":"7.6","Cell RNA - HDLM-2 [nTPM]":"35.2","Cell RNA - HEK 293 [nTPM]":"13.3","Cell RNA - HEL [nTPM]":"14.2","Cell RNA - HeLa [nTPM]":"12.1","Cell RNA - Hep G2 [nTPM]":"22.4","Cell RNA - HHSteC [nTPM]":"3.1","Cell RNA - HL-60 [nTPM]":"9.4","Cell RNA - HMC-1 [nTPM]":"9.5","Cell RNA - HSkMC [nTPM]":"2.6","Cell RNA - hTCEpi [nTPM]":"8.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.9","Cell RNA - hTERT-HME1 [nTPM]":"10.9","Cell RNA - hTERT-RPE1 [nTPM]":"6.1","Cell RNA - HUVEC TERT2 [nTPM]":"6.4","Cell RNA - JURKAT [nTPM]":"9.9","Cell RNA - K-562 [nTPM]":"10.4","Cell RNA - Karpas-707 [nTPM]":"17.1","Cell RNA - LHCN-M2 [nTPM]":"7.1","Cell RNA - MCF7 [nTPM]":"10.9","Cell RNA - MOLT-4 [nTPM]":"17.6","Cell RNA - NB-4 [nTPM]":"19.1","Cell RNA - NTERA-2 [nTPM]":"13.9","Cell RNA - OE19 [nTPM]":"24.6","Cell RNA - PC-3 [nTPM]":"6.1","Cell RNA - REH [nTPM]":"10.3","Cell RNA - RH-30 [nTPM]":"8.3","Cell RNA - RPMI-8226 [nTPM]":"19.4","Cell RNA - RPTEC TERT1 [nTPM]":"20.8","Cell RNA - RT4 [nTPM]":"11.6","Cell RNA - SCLC-21H [nTPM]":"14.0","Cell RNA - SH-SY5Y [nTPM]":"13.4","Cell RNA - SiHa [nTPM]":"7.6","Cell RNA - SK-BR-3 [nTPM]":"24.1","Cell RNA - SK-MEL-30 [nTPM]":"9.2","Cell RNA - SuSa [nTPM]":"7.0","Cell RNA - T-47d [nTPM]":"8.8","Cell RNA - THP-1 [nTPM]":"7.7","Cell RNA - TIME [nTPM]":"7.6","Cell RNA - U-138 MG [nTPM]":"5.5","Cell RNA - U-2 OS [nTPM]":"6.4","Cell RNA - U-2197 [nTPM]":"6.1","Cell RNA - U-251 MG [nTPM]":"5.9","Cell RNA - U-266\/70 [nTPM]":"13.3","Cell RNA - U-266\/84 [nTPM]":"11.5","Cell RNA - U-698 [nTPM]":"18.2","Cell RNA - U-87 MG [nTPM]":"6.1","Cell RNA - U-937 [nTPM]":"16.5","Cell RNA - WM-115 [nTPM]":"3.9","Blood RNA - basophil [nTPM]":"13.1","Blood RNA - classical monocyte [nTPM]":"8.2","Blood RNA - eosinophil [nTPM]":"6.2","Blood RNA - gdT-cell [nTPM]":"11.1","Blood RNA - intermediate monocyte [nTPM]":"6.9","Blood RNA - MAIT T-cell [nTPM]":"11.5","Blood RNA - memory B-cell [nTPM]":"20.9","Blood RNA - memory CD4 T-cell [nTPM]":"11.2","Blood RNA - memory CD8 T-cell [nTPM]":"9.7","Blood RNA - myeloid DC [nTPM]":"9.7","Blood RNA - naive B-cell [nTPM]":"14.7","Blood RNA - naive CD4 T-cell [nTPM]":"16.9","Blood RNA - naive CD8 T-cell [nTPM]":"13.4","Blood RNA - neutrophil [nTPM]":"5.2","Blood RNA - NK-cell [nTPM]":"8.7","Blood RNA - non-classical monocyte [nTPM]":"8.4","Blood RNA - plasmacytoid DC [nTPM]":"10.1","Blood RNA - T-reg [nTPM]":"18.3","Blood RNA - total PBMC [nTPM]":"6.9","Brain RNA - amygdala [nTPM]":"15.9","Brain RNA - basal ganglia [nTPM]":"21.1","Brain RNA - cerebellum [nTPM]":"19.4","Brain RNA - cerebral cortex [nTPM]":"21.1","Brain RNA - hippocampal formation [nTPM]":"15.5","Brain RNA - hypothalamus [nTPM]":"17.1","Brain RNA - medulla oblongata [nTPM]":"17.7","Brain RNA - midbrain [nTPM]":"16.4","Brain RNA - pons [nTPM]":"17.3","Brain RNA - spinal cord [nTPM]":"15.5","Brain RNA - thalamus [nTPM]":"17.9","Brain RNA - white matter [nTPM]":"20.4","Single Cell Type RNA - Adipocytes [nTPM]":"5.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.1","Single Cell Type RNA - Astrocytes [nTPM]":"155.1","Single Cell Type RNA - B-cells [nTPM]":"11.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"5.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"5.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.3","Single Cell Type RNA - dendritic cells [nTPM]":"6.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"13.3","Single Cell Type RNA - Early spermatids [nTPM]":"74.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.2","Single Cell Type RNA - Endothelial cells [nTPM]":"4.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"13.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"88.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.5","Single Cell Type RNA - Fibroblasts [nTPM]":"6.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.0","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"2.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"6.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.8","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"93.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.5","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"4.9","Single Cell Type RNA - Late spermatids [nTPM]":"39.0","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"4.3","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"114.3","Single Cell Type RNA - monocytes [nTPM]":"6.4","Single Cell Type RNA - Muller glia cells [nTPM]":"20.3","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"121.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"211.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.6","Single Cell Type RNA - Paneth cells [nTPM]":"8.3","Single Cell Type RNA - Peritubular cells [nTPM]":"5.7","Single Cell Type RNA - Plasma cells [nTPM]":"13.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.0","Single Cell Type RNA - Spermatocytes [nTPM]":"35.5","Single Cell Type RNA - Spermatogonia [nTPM]":"5.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.6","Single Cell Type RNA - T-cells [nTPM]":"9.2","Single Cell Type RNA - Theca cells [nTPM]":"7.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.1","Single Cell Type RNA - Urothelial cells [nTPM]":"6.0"},{"Gene":"CANT1","Gene synonym":["SCAN-1","SHAPY"],"Ensembl":"ENSG00000171302","Gene description":"Calcium activated nucleotidase 1","Uniprot":["Q8WVQ1"],"Chromosome":"17","Position":"78991716-79009867","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"139.5","Intestinal goblet cells":"155.6","Syncytiotrophoblasts":"101.5","Undifferentiated cells":"100.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"OE19":"445.4","T-47d":"282.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019627","HPA019639","HPA022818"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3300000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 27: Mucus-secreting cells - Mucin production","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA019627":"AB_1845969","HPA019639":"AB_1845970","HPA022818":"AB_1845971"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.41e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.90e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.21e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.23e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.8","Tissue RNA - adrenal gland [nTPM]":"23.9","Tissue RNA - amygdala [nTPM]":"10.4","Tissue RNA - appendix [nTPM]":"24.7","Tissue RNA - basal ganglia [nTPM]":"12.4","Tissue RNA - bone marrow [nTPM]":"19.1","Tissue RNA - breast [nTPM]":"25.4","Tissue RNA - cerebellum [nTPM]":"13.6","Tissue RNA - cerebral cortex [nTPM]":"11.3","Tissue RNA - cervix [nTPM]":"32.3","Tissue RNA - choroid plexus [nTPM]":"13.8","Tissue RNA - colon [nTPM]":"89.2","Tissue RNA - duodenum [nTPM]":"51.9","Tissue RNA - endometrium 1 [nTPM]":"17.4","Tissue RNA - epididymis [nTPM]":"8.7","Tissue RNA - esophagus [nTPM]":"44.8","Tissue RNA - fallopian tube [nTPM]":"18.2","Tissue RNA - gallbladder [nTPM]":"25.2","Tissue RNA - heart muscle [nTPM]":"17.0","Tissue RNA - hippocampal formation [nTPM]":"11.1","Tissue RNA - hypothalamus [nTPM]":"12.6","Tissue RNA - kidney [nTPM]":"16.1","Tissue RNA - liver [nTPM]":"17.3","Tissue RNA - lung [nTPM]":"16.4","Tissue RNA - lymph node [nTPM]":"15.2","Tissue RNA - medulla oblongata [nTPM]":"14.6","Tissue RNA - midbrain [nTPM]":"14.5","Tissue RNA - ovary [nTPM]":"14.6","Tissue RNA - pancreas [nTPM]":"19.6","Tissue RNA - parathyroid gland [nTPM]":"24.5","Tissue RNA - pituitary gland [nTPM]":"17.5","Tissue RNA - placenta [nTPM]":"25.9","Tissue RNA - pons [nTPM]":"13.9","Tissue RNA - prostate [nTPM]":"71.8","Tissue RNA - rectum [nTPM]":"82.8","Tissue RNA - retina [nTPM]":"7.4","Tissue RNA - salivary gland [nTPM]":"62.7","Tissue RNA - seminal vesicle [nTPM]":"32.4","Tissue RNA - skeletal muscle [nTPM]":"14.9","Tissue RNA - skin 1 [nTPM]":"14.9","Tissue RNA - small intestine [nTPM]":"55.5","Tissue RNA - smooth muscle [nTPM]":"15.5","Tissue RNA - spinal cord [nTPM]":"13.8","Tissue RNA - spleen [nTPM]":"26.5","Tissue RNA - stomach 1 [nTPM]":"51.1","Tissue RNA - testis [nTPM]":"20.7","Tissue RNA - thalamus [nTPM]":"14.5","Tissue RNA - thymus [nTPM]":"14.7","Tissue RNA - thyroid gland [nTPM]":"13.9","Tissue RNA - tongue [nTPM]":"12.4","Tissue RNA - tonsil [nTPM]":"15.1","Tissue RNA - urinary bladder [nTPM]":"16.7","Tissue RNA - vagina [nTPM]":"21.7","Tissue RNA - white matter [nTPM]":"17.8","Cell RNA - A-431 [nTPM]":"106.5","Cell RNA - A549 [nTPM]":"112.1","Cell RNA - AF22 [nTPM]":"31.9","Cell RNA - AN3-CA [nTPM]":"46.3","Cell RNA - ASC diff [nTPM]":"29.7","Cell RNA - ASC TERT1 [nTPM]":"35.2","Cell RNA - BEWO [nTPM]":"38.9","Cell RNA - BJ [nTPM]":"66.0","Cell RNA - BJ hTERT+ [nTPM]":"51.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"66.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"55.9","Cell RNA - CACO-2 [nTPM]":"53.8","Cell RNA - CAPAN-2 [nTPM]":"99.6","Cell RNA - Daudi [nTPM]":"25.3","Cell RNA - EFO-21 [nTPM]":"36.1","Cell RNA - fHDF\/TERT166 [nTPM]":"46.1","Cell RNA - GAMG [nTPM]":"83.0","Cell RNA - HaCaT [nTPM]":"53.7","Cell RNA - HAP1 [nTPM]":"27.1","Cell RNA - HBEC3-KT [nTPM]":"49.8","Cell RNA - HBF TERT88 [nTPM]":"68.4","Cell RNA - HDLM-2 [nTPM]":"43.0","Cell RNA - HEK 293 [nTPM]":"46.4","Cell RNA - HEL [nTPM]":"33.7","Cell RNA - HeLa [nTPM]":"34.1","Cell RNA - Hep G2 [nTPM]":"45.9","Cell RNA - HHSteC [nTPM]":"25.0","Cell RNA - HL-60 [nTPM]":"33.0","Cell RNA - HMC-1 [nTPM]":"51.6","Cell RNA - HSkMC [nTPM]":"33.7","Cell RNA - hTCEpi [nTPM]":"32.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"62.7","Cell RNA - hTERT-HME1 [nTPM]":"34.2","Cell RNA - hTERT-RPE1 [nTPM]":"40.9","Cell RNA - HUVEC TERT2 [nTPM]":"116.1","Cell RNA - JURKAT [nTPM]":"42.5","Cell RNA - K-562 [nTPM]":"42.3","Cell RNA - Karpas-707 [nTPM]":"43.2","Cell RNA - LHCN-M2 [nTPM]":"46.4","Cell RNA - MCF7 [nTPM]":"58.4","Cell RNA - MOLT-4 [nTPM]":"50.2","Cell RNA - NB-4 [nTPM]":"19.8","Cell RNA - NTERA-2 [nTPM]":"22.1","Cell RNA - OE19 [nTPM]":"445.4","Cell RNA - PC-3 [nTPM]":"103.1","Cell RNA - REH [nTPM]":"27.6","Cell RNA - RH-30 [nTPM]":"51.8","Cell RNA - RPMI-8226 [nTPM]":"29.8","Cell RNA - RPTEC TERT1 [nTPM]":"29.8","Cell RNA - RT4 [nTPM]":"53.5","Cell RNA - SCLC-21H [nTPM]":"45.6","Cell RNA - SH-SY5Y [nTPM]":"45.4","Cell RNA - SiHa [nTPM]":"33.9","Cell RNA - SK-BR-3 [nTPM]":"227.2","Cell RNA - SK-MEL-30 [nTPM]":"50.2","Cell RNA - SuSa [nTPM]":"50.3","Cell RNA - T-47d [nTPM]":"282.6","Cell RNA - THP-1 [nTPM]":"38.6","Cell RNA - TIME [nTPM]":"56.6","Cell RNA - U-138 MG [nTPM]":"101.9","Cell RNA - U-2 OS [nTPM]":"90.5","Cell RNA - U-2197 [nTPM]":"46.4","Cell RNA - U-251 MG [nTPM]":"83.1","Cell RNA - U-266\/70 [nTPM]":"48.9","Cell RNA - U-266\/84 [nTPM]":"43.8","Cell RNA - U-698 [nTPM]":"24.3","Cell RNA - U-87 MG [nTPM]":"64.4","Cell RNA - U-937 [nTPM]":"24.9","Cell RNA - WM-115 [nTPM]":"65.3","Blood RNA - basophil [nTPM]":"6.3","Blood RNA - classical monocyte [nTPM]":"4.0","Blood RNA - eosinophil [nTPM]":"8.7","Blood RNA - gdT-cell [nTPM]":"5.5","Blood RNA - intermediate monocyte [nTPM]":"4.4","Blood RNA - MAIT T-cell [nTPM]":"5.7","Blood RNA - memory B-cell [nTPM]":"3.9","Blood RNA - memory CD4 T-cell [nTPM]":"4.3","Blood RNA - memory CD8 T-cell [nTPM]":"4.8","Blood RNA - myeloid DC [nTPM]":"3.8","Blood RNA - naive B-cell [nTPM]":"2.5","Blood RNA - naive CD4 T-cell [nTPM]":"4.1","Blood RNA - naive CD8 T-cell [nTPM]":"4.1","Blood RNA - neutrophil [nTPM]":"17.4","Blood RNA - NK-cell [nTPM]":"3.1","Blood RNA - non-classical monocyte [nTPM]":"3.0","Blood RNA - plasmacytoid DC [nTPM]":"2.7","Blood RNA - T-reg [nTPM]":"3.6","Blood RNA - total PBMC [nTPM]":"4.6","Brain RNA - amygdala [nTPM]":"10.4","Brain RNA - basal ganglia [nTPM]":"12.4","Brain RNA - cerebellum [nTPM]":"13.6","Brain RNA - cerebral cortex [nTPM]":"11.3","Brain RNA - hippocampal formation [nTPM]":"11.1","Brain RNA - hypothalamus [nTPM]":"12.6","Brain RNA - medulla oblongata [nTPM]":"14.6","Brain RNA - midbrain [nTPM]":"14.5","Brain RNA - pons [nTPM]":"13.9","Brain RNA - spinal cord [nTPM]":"13.8","Brain RNA - thalamus [nTPM]":"14.5","Brain RNA - white matter [nTPM]":"17.8","Single Cell Type RNA - Adipocytes [nTPM]":"12.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.6","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"11.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"6.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"49.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"15.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"36.6","Single Cell Type RNA - dendritic cells [nTPM]":"8.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"139.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"34.7","Single Cell Type RNA - Early spermatids [nTPM]":"14.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.1","Single Cell Type RNA - Endothelial cells [nTPM]":"16.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"51.0","Single Cell Type RNA - Erythroid cells [nTPM]":"15.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"28.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"39.4","Single Cell Type RNA - Fibroblasts [nTPM]":"13.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"38.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.0","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"20.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"41.7","Single Cell Type RNA - Hepatocytes [nTPM]":"14.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.9","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"155.6","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"12.4","Single Cell Type RNA - Langerhans cells [nTPM]":"9.5","Single Cell Type RNA - Late spermatids [nTPM]":"15.7","Single Cell Type RNA - Leydig cells [nTPM]":"11.8","Single Cell Type RNA - Macrophages [nTPM]":"14.2","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"18.1","Single Cell Type RNA - Muller glia cells [nTPM]":"8.1","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"37.7","Single Cell Type RNA - Paneth cells [nTPM]":"55.8","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"16.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"33.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"39.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.3","Single Cell Type RNA - Spermatocytes [nTPM]":"23.9","Single Cell Type RNA - Spermatogonia [nTPM]":"5.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"101.5","Single Cell Type RNA - T-cells [nTPM]":"11.1","Single Cell Type RNA - Theca cells [nTPM]":"11.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"100.2","Single Cell Type RNA - Urothelial cells [nTPM]":"19.4"},{"Gene":"CAPN1","Gene synonym":["CANP","CANPL1","muCANP","muCL"],"Ensembl":"ENSG00000014216","Gene description":"Calpain 1","Uniprot":["P07384"],"Chromosome":"11","Position":"65180566-65212006","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"276.2"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RT4":"516.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005992"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9100000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA005992":"AB_1845924"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.30e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.06e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.70e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Tissue RNA - adipose tissue [nTPM]":"44.8","Tissue RNA - adrenal gland [nTPM]":"43.1","Tissue RNA - amygdala [nTPM]":"27.8","Tissue RNA - appendix [nTPM]":"51.9","Tissue RNA - basal ganglia [nTPM]":"26.1","Tissue RNA - bone marrow [nTPM]":"66.5","Tissue RNA - breast [nTPM]":"48.4","Tissue RNA - cerebellum [nTPM]":"29.7","Tissue RNA - cerebral cortex [nTPM]":"30.1","Tissue RNA - cervix [nTPM]":"80.9","Tissue RNA - choroid plexus [nTPM]":"28.3","Tissue RNA - colon [nTPM]":"78.6","Tissue RNA - duodenum [nTPM]":"80.4","Tissue RNA - endometrium 1 [nTPM]":"56.3","Tissue RNA - epididymis [nTPM]":"27.5","Tissue RNA - esophagus [nTPM]":"276.2","Tissue RNA - fallopian tube [nTPM]":"92.3","Tissue RNA - gallbladder [nTPM]":"55.5","Tissue RNA - heart muscle [nTPM]":"53.1","Tissue RNA - hippocampal formation [nTPM]":"27.7","Tissue RNA - hypothalamus [nTPM]":"33.0","Tissue RNA - kidney [nTPM]":"53.1","Tissue RNA - liver [nTPM]":"44.3","Tissue RNA - lung [nTPM]":"56.9","Tissue RNA - lymph node [nTPM]":"57.0","Tissue RNA - medulla oblongata [nTPM]":"41.4","Tissue RNA - midbrain [nTPM]":"31.5","Tissue RNA - ovary [nTPM]":"44.5","Tissue RNA - pancreas [nTPM]":"71.7","Tissue RNA - parathyroid gland [nTPM]":"36.6","Tissue RNA - pituitary gland [nTPM]":"40.8","Tissue RNA - placenta [nTPM]":"56.2","Tissue RNA - pons [nTPM]":"43.4","Tissue RNA - prostate [nTPM]":"62.1","Tissue RNA - rectum [nTPM]":"57.6","Tissue RNA - retina [nTPM]":"9.6","Tissue RNA - salivary gland [nTPM]":"118.7","Tissue RNA - seminal vesicle [nTPM]":"67.4","Tissue RNA - skeletal muscle [nTPM]":"84.8","Tissue RNA - skin 1 [nTPM]":"125.1","Tissue RNA - small intestine [nTPM]":"88.1","Tissue RNA - smooth muscle [nTPM]":"45.3","Tissue RNA - spinal cord [nTPM]":"33.9","Tissue RNA - spleen [nTPM]":"50.2","Tissue RNA - stomach 1 [nTPM]":"65.5","Tissue RNA - testis [nTPM]":"6.1","Tissue RNA - thalamus [nTPM]":"37.9","Tissue RNA - thymus [nTPM]":"49.5","Tissue RNA - thyroid gland [nTPM]":"71.5","Tissue RNA - tongue [nTPM]":"55.3","Tissue RNA - tonsil [nTPM]":"86.4","Tissue RNA - urinary bladder [nTPM]":"83.4","Tissue RNA - vagina [nTPM]":"117.4","Tissue RNA - white matter [nTPM]":"27.4","Cell RNA - A-431 [nTPM]":"285.6","Cell RNA - A549 [nTPM]":"147.9","Cell RNA - AF22 [nTPM]":"42.9","Cell RNA - AN3-CA [nTPM]":"97.2","Cell RNA - ASC diff [nTPM]":"77.9","Cell RNA - ASC TERT1 [nTPM]":"104.3","Cell RNA - BEWO [nTPM]":"127.0","Cell RNA - BJ [nTPM]":"84.1","Cell RNA - BJ hTERT+ [nTPM]":"144.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"103.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"74.9","Cell RNA - CACO-2 [nTPM]":"94.8","Cell RNA - CAPAN-2 [nTPM]":"250.2","Cell RNA - Daudi [nTPM]":"71.2","Cell RNA - EFO-21 [nTPM]":"136.0","Cell RNA - fHDF\/TERT166 [nTPM]":"179.3","Cell RNA - GAMG [nTPM]":"111.1","Cell RNA - HaCaT [nTPM]":"409.8","Cell RNA - HAP1 [nTPM]":"60.9","Cell RNA - HBEC3-KT [nTPM]":"366.9","Cell RNA - HBF TERT88 [nTPM]":"32.2","Cell RNA - HDLM-2 [nTPM]":"76.4","Cell RNA - HEK 293 [nTPM]":"44.1","Cell RNA - HEL [nTPM]":"170.8","Cell RNA - HeLa [nTPM]":"80.4","Cell RNA - Hep G2 [nTPM]":"93.7","Cell RNA - HHSteC [nTPM]":"76.2","Cell RNA - HL-60 [nTPM]":"40.6","Cell RNA - HMC-1 [nTPM]":"228.0","Cell RNA - HSkMC [nTPM]":"107.3","Cell RNA - hTCEpi [nTPM]":"196.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"85.9","Cell RNA - hTERT-HME1 [nTPM]":"43.2","Cell RNA - hTERT-RPE1 [nTPM]":"92.6","Cell RNA - HUVEC TERT2 [nTPM]":"178.5","Cell RNA - JURKAT [nTPM]":"50.6","Cell RNA - K-562 [nTPM]":"103.1","Cell RNA - Karpas-707 [nTPM]":"55.9","Cell RNA - LHCN-M2 [nTPM]":"87.4","Cell RNA - MCF7 [nTPM]":"181.8","Cell RNA - MOLT-4 [nTPM]":"83.1","Cell RNA - NB-4 [nTPM]":"130.6","Cell RNA - NTERA-2 [nTPM]":"120.5","Cell RNA - OE19 [nTPM]":"145.2","Cell RNA - PC-3 [nTPM]":"133.8","Cell RNA - REH [nTPM]":"80.7","Cell RNA - RH-30 [nTPM]":"43.0","Cell RNA - RPMI-8226 [nTPM]":"43.2","Cell RNA - RPTEC TERT1 [nTPM]":"138.1","Cell RNA - RT4 [nTPM]":"516.5","Cell RNA - SCLC-21H [nTPM]":"76.2","Cell RNA - SH-SY5Y [nTPM]":"55.7","Cell RNA - SiHa [nTPM]":"87.4","Cell RNA - SK-BR-3 [nTPM]":"331.4","Cell RNA - SK-MEL-30 [nTPM]":"80.3","Cell RNA - SuSa [nTPM]":"45.8","Cell RNA - T-47d [nTPM]":"142.8","Cell RNA - THP-1 [nTPM]":"77.9","Cell RNA - TIME [nTPM]":"147.1","Cell RNA - U-138 MG [nTPM]":"73.1","Cell RNA - U-2 OS [nTPM]":"50.5","Cell RNA - U-2197 [nTPM]":"159.0","Cell RNA - U-251 MG [nTPM]":"38.5","Cell RNA - U-266\/70 [nTPM]":"33.8","Cell RNA - U-266\/84 [nTPM]":"26.9","Cell RNA - U-698 [nTPM]":"86.6","Cell RNA - U-87 MG [nTPM]":"127.5","Cell RNA - U-937 [nTPM]":"48.8","Cell RNA - WM-115 [nTPM]":"82.3","Blood RNA - basophil [nTPM]":"87.6","Blood RNA - classical monocyte [nTPM]":"57.5","Blood RNA - eosinophil [nTPM]":"77.9","Blood RNA - gdT-cell [nTPM]":"39.4","Blood RNA - intermediate monocyte [nTPM]":"51.2","Blood RNA - MAIT T-cell [nTPM]":"31.0","Blood RNA - memory B-cell [nTPM]":"30.8","Blood RNA - memory CD4 T-cell [nTPM]":"30.7","Blood RNA - memory CD8 T-cell [nTPM]":"35.8","Blood RNA - myeloid DC [nTPM]":"48.4","Blood RNA - naive B-cell [nTPM]":"31.7","Blood RNA - naive CD4 T-cell [nTPM]":"17.6","Blood RNA - naive CD8 T-cell [nTPM]":"24.9","Blood RNA - neutrophil [nTPM]":"33.1","Blood RNA - NK-cell [nTPM]":"34.8","Blood RNA - non-classical monocyte [nTPM]":"30.4","Blood RNA - plasmacytoid DC [nTPM]":"38.1","Blood RNA - T-reg [nTPM]":"35.9","Blood RNA - total PBMC [nTPM]":"74.8","Brain RNA - amygdala [nTPM]":"27.8","Brain RNA - basal ganglia [nTPM]":"26.1","Brain RNA - cerebellum [nTPM]":"29.7","Brain RNA - cerebral cortex [nTPM]":"30.1","Brain RNA - hippocampal formation [nTPM]":"27.7","Brain RNA - hypothalamus [nTPM]":"33.0","Brain RNA - medulla oblongata [nTPM]":"41.4","Brain RNA - midbrain [nTPM]":"31.5","Brain RNA - pons [nTPM]":"43.4","Brain RNA - spinal cord [nTPM]":"33.9","Brain RNA - thalamus [nTPM]":"37.9","Brain RNA - white matter [nTPM]":"27.4","Single Cell Type RNA - Adipocytes [nTPM]":"27.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.9","Single Cell Type RNA - Astrocytes [nTPM]":"21.5","Single Cell Type RNA - B-cells [nTPM]":"39.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"59.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"127.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"120.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"56.9","Single Cell Type RNA - Bipolar cells [nTPM]":"10.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"44.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"36.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"22.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"74.4","Single Cell Type RNA - Club cells [nTPM]":"81.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"77.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"238.5","Single Cell Type RNA - dendritic cells [nTPM]":"61.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"184.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"39.2","Single Cell Type RNA - Ductal cells [nTPM]":"180.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"41.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.3","Single Cell Type RNA - Endothelial cells [nTPM]":"31.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"44.3","Single Cell Type RNA - Erythroid cells [nTPM]":"58.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"115.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"111.7","Single Cell Type RNA - Fibroblasts [nTPM]":"39.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"57.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"58.2","Single Cell Type RNA - granulocytes [nTPM]":"46.9","Single Cell Type RNA - Granulosa cells [nTPM]":"48.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"37.9","Single Cell Type RNA - Hepatocytes [nTPM]":"36.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"88.7","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"76.9","Single Cell Type RNA - Ionocytes [nTPM]":"59.0","Single Cell Type RNA - Kupffer cells [nTPM]":"51.2","Single Cell Type RNA - Langerhans cells [nTPM]":"34.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.0","Single Cell Type RNA - Leydig cells [nTPM]":"43.5","Single Cell Type RNA - Macrophages [nTPM]":"67.1","Single Cell Type RNA - Melanocytes [nTPM]":"48.0","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"112.7","Single Cell Type RNA - Muller glia cells [nTPM]":"38.5","Single Cell Type RNA - NK-cells [nTPM]":"61.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"179.4","Single Cell Type RNA - Paneth cells [nTPM]":"124.1","Single Cell Type RNA - Peritubular cells [nTPM]":"50.8","Single Cell Type RNA - Plasma cells [nTPM]":"17.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"78.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"155.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"34.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"71.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.2","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"25.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"36.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"2.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"102.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"68.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"196.6","Single Cell Type RNA - T-cells [nTPM]":"40.2","Single Cell Type RNA - Theca cells [nTPM]":"35.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"125.3","Single Cell Type RNA - Urothelial cells [nTPM]":"156.6"},{"Gene":"CAPN10","Gene synonym":[],"Ensembl":"ENSG00000142330","Gene description":"Calpain 10","Uniprot":["Q9HC96"],"Chromosome":"2","Position":"240586734-240617705","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"48.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004170","HPA056098"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 62: Horizontal cells - Visual perception","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA004170":"AB_1078381","HPA056098":"AB_2683037"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.47e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.78e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.94e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-3"},"Tissue RNA - adipose tissue [nTPM]":"10.0","Tissue RNA - adrenal gland [nTPM]":"18.6","Tissue RNA - amygdala [nTPM]":"16.8","Tissue RNA - appendix [nTPM]":"6.8","Tissue RNA - basal ganglia [nTPM]":"16.2","Tissue RNA - bone marrow [nTPM]":"7.9","Tissue RNA - breast [nTPM]":"9.6","Tissue RNA - cerebellum [nTPM]":"21.0","Tissue RNA - cerebral cortex [nTPM]":"25.0","Tissue RNA - cervix [nTPM]":"11.8","Tissue RNA - choroid plexus [nTPM]":"16.5","Tissue RNA - colon [nTPM]":"12.7","Tissue RNA - duodenum [nTPM]":"13.1","Tissue RNA - endometrium 1 [nTPM]":"10.7","Tissue RNA - epididymis [nTPM]":"3.7","Tissue RNA - esophagus [nTPM]":"14.5","Tissue RNA - fallopian tube [nTPM]":"13.7","Tissue RNA - gallbladder [nTPM]":"6.1","Tissue RNA - heart muscle [nTPM]":"24.6","Tissue RNA - hippocampal formation [nTPM]":"17.9","Tissue RNA - hypothalamus [nTPM]":"14.0","Tissue RNA - kidney [nTPM]":"23.8","Tissue RNA - liver [nTPM]":"14.7","Tissue RNA - lung [nTPM]":"12.2","Tissue RNA - lymph node [nTPM]":"10.6","Tissue RNA - medulla oblongata [nTPM]":"15.6","Tissue RNA - midbrain [nTPM]":"15.8","Tissue RNA - ovary [nTPM]":"13.3","Tissue RNA - pancreas [nTPM]":"12.6","Tissue RNA - parathyroid gland [nTPM]":"5.3","Tissue RNA - pituitary gland [nTPM]":"18.1","Tissue RNA - placenta [nTPM]":"4.5","Tissue RNA - pons [nTPM]":"15.4","Tissue RNA - prostate [nTPM]":"14.9","Tissue RNA - rectum [nTPM]":"7.1","Tissue RNA - retina [nTPM]":"10.6","Tissue RNA - salivary gland [nTPM]":"10.2","Tissue RNA - seminal vesicle [nTPM]":"5.3","Tissue RNA - skeletal muscle [nTPM]":"5.8","Tissue RNA - skin 1 [nTPM]":"12.1","Tissue RNA - small intestine [nTPM]":"14.0","Tissue RNA - smooth muscle [nTPM]":"2.8","Tissue RNA - spinal cord [nTPM]":"12.6","Tissue RNA - spleen [nTPM]":"29.8","Tissue RNA - stomach 1 [nTPM]":"15.8","Tissue RNA - testis [nTPM]":"17.0","Tissue RNA - thalamus [nTPM]":"16.7","Tissue RNA - thymus [nTPM]":"6.4","Tissue RNA - thyroid gland [nTPM]":"13.2","Tissue RNA - tongue [nTPM]":"2.8","Tissue RNA - tonsil [nTPM]":"5.4","Tissue RNA - urinary bladder [nTPM]":"11.1","Tissue RNA - vagina [nTPM]":"10.0","Tissue RNA - white matter [nTPM]":"16.8","Cell RNA - A-431 [nTPM]":"8.0","Cell RNA - A549 [nTPM]":"11.2","Cell RNA - AF22 [nTPM]":"11.2","Cell RNA - AN3-CA [nTPM]":"9.5","Cell RNA - ASC diff [nTPM]":"4.5","Cell RNA - ASC TERT1 [nTPM]":"3.6","Cell RNA - BEWO [nTPM]":"19.7","Cell RNA - BJ [nTPM]":"9.9","Cell RNA - BJ hTERT+ [nTPM]":"4.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.9","Cell RNA - CACO-2 [nTPM]":"8.7","Cell RNA - CAPAN-2 [nTPM]":"18.7","Cell RNA - Daudi [nTPM]":"5.9","Cell RNA - EFO-21 [nTPM]":"3.5","Cell RNA - fHDF\/TERT166 [nTPM]":"3.6","Cell RNA - GAMG [nTPM]":"8.9","Cell RNA - HaCaT [nTPM]":"12.7","Cell RNA - HAP1 [nTPM]":"3.0","Cell RNA - HBEC3-KT [nTPM]":"6.6","Cell RNA - HBF TERT88 [nTPM]":"3.3","Cell RNA - HDLM-2 [nTPM]":"23.0","Cell RNA - HEK 293 [nTPM]":"19.8","Cell RNA - HEL [nTPM]":"10.9","Cell RNA - HeLa [nTPM]":"20.4","Cell RNA - Hep G2 [nTPM]":"16.0","Cell RNA - HHSteC [nTPM]":"7.1","Cell RNA - HL-60 [nTPM]":"7.1","Cell RNA - HMC-1 [nTPM]":"15.3","Cell RNA - HSkMC [nTPM]":"2.6","Cell RNA - hTCEpi [nTPM]":"4.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.7","Cell RNA - hTERT-HME1 [nTPM]":"2.7","Cell RNA - hTERT-RPE1 [nTPM]":"6.7","Cell RNA - HUVEC TERT2 [nTPM]":"5.2","Cell RNA - JURKAT [nTPM]":"16.8","Cell RNA - K-562 [nTPM]":"12.5","Cell RNA - Karpas-707 [nTPM]":"7.3","Cell RNA - LHCN-M2 [nTPM]":"2.8","Cell RNA - MCF7 [nTPM]":"7.1","Cell RNA - MOLT-4 [nTPM]":"16.2","Cell RNA - NB-4 [nTPM]":"27.5","Cell RNA - NTERA-2 [nTPM]":"17.4","Cell RNA - OE19 [nTPM]":"9.5","Cell RNA - PC-3 [nTPM]":"8.1","Cell RNA - REH [nTPM]":"15.5","Cell RNA - RH-30 [nTPM]":"8.1","Cell RNA - RPMI-8226 [nTPM]":"13.1","Cell RNA - RPTEC TERT1 [nTPM]":"9.9","Cell RNA - RT4 [nTPM]":"9.8","Cell RNA - SCLC-21H [nTPM]":"28.1","Cell RNA - SH-SY5Y [nTPM]":"22.0","Cell RNA - SiHa [nTPM]":"6.3","Cell RNA - SK-BR-3 [nTPM]":"9.3","Cell RNA - SK-MEL-30 [nTPM]":"13.8","Cell RNA - SuSa [nTPM]":"3.5","Cell RNA - T-47d [nTPM]":"4.8","Cell RNA - THP-1 [nTPM]":"9.3","Cell RNA - TIME [nTPM]":"8.6","Cell RNA - U-138 MG [nTPM]":"11.0","Cell RNA - U-2 OS [nTPM]":"9.7","Cell RNA - U-2197 [nTPM]":"9.5","Cell RNA - U-251 MG [nTPM]":"11.8","Cell RNA - U-266\/70 [nTPM]":"16.3","Cell RNA - U-266\/84 [nTPM]":"4.2","Cell RNA - U-698 [nTPM]":"10.7","Cell RNA - U-87 MG [nTPM]":"10.4","Cell RNA - U-937 [nTPM]":"12.8","Cell RNA - WM-115 [nTPM]":"11.0","Blood RNA - basophil [nTPM]":"1.5","Blood RNA - classical monocyte [nTPM]":"0.9","Blood RNA - eosinophil [nTPM]":"1.8","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"1.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"4.1","Blood RNA - NK-cell [nTPM]":"3.0","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"1.3","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"16.8","Brain RNA - basal ganglia [nTPM]":"16.2","Brain RNA - cerebellum [nTPM]":"21.0","Brain RNA - cerebral cortex [nTPM]":"25.0","Brain RNA - hippocampal formation [nTPM]":"17.9","Brain RNA - hypothalamus [nTPM]":"14.0","Brain RNA - medulla oblongata [nTPM]":"15.6","Brain RNA - midbrain [nTPM]":"15.8","Brain RNA - pons [nTPM]":"15.4","Brain RNA - spinal cord [nTPM]":"12.6","Brain RNA - thalamus [nTPM]":"16.7","Brain RNA - white matter [nTPM]":"16.8","Single Cell Type RNA - Adipocytes [nTPM]":"8.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.0","Single Cell Type RNA - Astrocytes [nTPM]":"19.6","Single Cell Type RNA - B-cells [nTPM]":"7.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"14.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"4.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.4","Single Cell Type RNA - dendritic cells [nTPM]":"14.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"13.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.7","Single Cell Type RNA - Endothelial cells [nTPM]":"7.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.3","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.2","Single Cell Type RNA - Fibroblasts [nTPM]":"5.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.8","Single Cell Type RNA - granulocytes [nTPM]":"22.9","Single Cell Type RNA - Granulosa cells [nTPM]":"11.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"3.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.7","Single Cell Type RNA - Horizontal cells [nTPM]":"48.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.3","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1.7","Single Cell Type RNA - Late spermatids [nTPM]":"2.6","Single Cell Type RNA - Leydig cells [nTPM]":"9.0","Single Cell Type RNA - Macrophages [nTPM]":"7.8","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"7.7","Single Cell Type RNA - Muller glia cells [nTPM]":"13.4","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.8","Single Cell Type RNA - Paneth cells [nTPM]":"4.6","Single Cell Type RNA - Peritubular cells [nTPM]":"9.4","Single Cell Type RNA - Plasma cells [nTPM]":"7.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.6","Single Cell Type RNA - Spermatocytes [nTPM]":"12.6","Single Cell Type RNA - Spermatogonia [nTPM]":"7.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.5","Single Cell Type RNA - T-cells [nTPM]":"11.3","Single Cell Type RNA - Theca cells [nTPM]":"9.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.4","Single Cell Type RNA - Urothelial cells [nTPM]":"6.9"},{"Gene":"CAPN3","Gene synonym":["CANP3","LGMD2","LGMD2A","nCL-1","p94"],"Ensembl":"ENSG00000092529","Gene description":"Calpain 3","Uniprot":["P20807"],"Chromosome":"15","Position":"42359498-42412949","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Disease variant","Limb-girdle muscular dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"279.2","skeletal muscle":"905.9","tongue":"377.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"512.5","Late spermatids":"183.6","Melanocytes":"482.0","Oligodendrocytes":"220.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"10","RNA cancer specific FPKM":{"melanoma":"9.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"27","RNA cell line specific nTPM":{"SK-MEL-30":"238.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040052"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 23: Spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA040052":"AB_2676821"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.93e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Tissue RNA - adipose tissue [nTPM]":"13.5","Tissue RNA - adrenal gland [nTPM]":"8.8","Tissue RNA - amygdala [nTPM]":"136.1","Tissue RNA - appendix [nTPM]":"4.0","Tissue RNA - basal ganglia [nTPM]":"206.6","Tissue RNA - bone marrow [nTPM]":"47.6","Tissue RNA - breast [nTPM]":"14.1","Tissue RNA - cerebellum [nTPM]":"194.2","Tissue RNA - cerebral cortex [nTPM]":"243.3","Tissue RNA - cervix [nTPM]":"18.8","Tissue RNA - choroid plexus [nTPM]":"113.0","Tissue RNA - colon [nTPM]":"13.3","Tissue RNA - duodenum [nTPM]":"3.1","Tissue RNA - endometrium 1 [nTPM]":"11.2","Tissue RNA - epididymis [nTPM]":"163.7","Tissue RNA - esophagus [nTPM]":"14.5","Tissue RNA - fallopian tube [nTPM]":"13.7","Tissue RNA - gallbladder [nTPM]":"4.5","Tissue RNA - heart muscle [nTPM]":"16.1","Tissue RNA - hippocampal formation [nTPM]":"142.9","Tissue RNA - hypothalamus [nTPM]":"159.9","Tissue RNA - kidney [nTPM]":"93.6","Tissue RNA - liver [nTPM]":"36.9","Tissue RNA - lung [nTPM]":"21.5","Tissue RNA - lymph node [nTPM]":"7.0","Tissue RNA - medulla oblongata [nTPM]":"212.0","Tissue RNA - midbrain [nTPM]":"194.9","Tissue RNA - ovary [nTPM]":"15.7","Tissue RNA - pancreas [nTPM]":"8.7","Tissue RNA - parathyroid gland [nTPM]":"2.4","Tissue RNA - pituitary gland [nTPM]":"11.3","Tissue RNA - placenta [nTPM]":"3.0","Tissue RNA - pons [nTPM]":"212.1","Tissue RNA - prostate [nTPM]":"16.0","Tissue RNA - rectum [nTPM]":"5.3","Tissue RNA - retina [nTPM]":"7.5","Tissue RNA - salivary gland [nTPM]":"18.6","Tissue RNA - seminal vesicle [nTPM]":"5.2","Tissue RNA - skeletal muscle [nTPM]":"905.9","Tissue RNA - skin 1 [nTPM]":"54.9","Tissue RNA - small intestine [nTPM]":"14.0","Tissue RNA - smooth muscle [nTPM]":"4.7","Tissue RNA - spinal cord [nTPM]":"155.2","Tissue RNA - spleen [nTPM]":"19.1","Tissue RNA - stomach 1 [nTPM]":"8.9","Tissue RNA - testis [nTPM]":"30.8","Tissue RNA - thalamus [nTPM]":"187.8","Tissue RNA - thymus [nTPM]":"3.4","Tissue RNA - thyroid gland [nTPM]":"10.7","Tissue RNA - tongue [nTPM]":"377.4","Tissue RNA - tonsil [nTPM]":"5.1","Tissue RNA - urinary bladder [nTPM]":"11.7","Tissue RNA - vagina [nTPM]":"15.5","Tissue RNA - white matter [nTPM]":"279.2","Cell RNA - A-431 [nTPM]":"0.5","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"1.1","Cell RNA - ASC diff [nTPM]":"8.8","Cell RNA - ASC TERT1 [nTPM]":"6.1","Cell RNA - BEWO [nTPM]":"0.6","Cell RNA - BJ [nTPM]":"2.6","Cell RNA - BJ hTERT+ [nTPM]":"1.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.8","Cell RNA - CACO-2 [nTPM]":"1.2","Cell RNA - CAPAN-2 [nTPM]":"0.5","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.9","Cell RNA - fHDF\/TERT166 [nTPM]":"1.6","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"3.7","Cell RNA - HAP1 [nTPM]":"0.4","Cell RNA - HBEC3-KT [nTPM]":"3.5","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"0.9","Cell RNA - HEK 293 [nTPM]":"0.8","Cell RNA - HEL [nTPM]":"0.8","Cell RNA - HeLa [nTPM]":"0.8","Cell RNA - Hep G2 [nTPM]":"4.1","Cell RNA - HHSteC [nTPM]":"0.6","Cell RNA - HL-60 [nTPM]":"1.0","Cell RNA - HMC-1 [nTPM]":"1.5","Cell RNA - HSkMC [nTPM]":"4.7","Cell RNA - hTCEpi [nTPM]":"3.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.8","Cell RNA - hTERT-HME1 [nTPM]":"0.7","Cell RNA - hTERT-RPE1 [nTPM]":"1.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"1.8","Cell RNA - LHCN-M2 [nTPM]":"0.7","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"1.2","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.9","Cell RNA - REH [nTPM]":"1.1","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"1.9","Cell RNA - RPTEC TERT1 [nTPM]":"1.9","Cell RNA - RT4 [nTPM]":"1.3","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"238.0","Cell RNA - SuSa [nTPM]":"1.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"5.4","Cell RNA - TIME [nTPM]":"0.9","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"2.6","Cell RNA - U-251 MG [nTPM]":"0.7","Cell RNA - U-266\/70 [nTPM]":"1.5","Cell RNA - U-266\/84 [nTPM]":"2.1","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"2.4","Cell RNA - WM-115 [nTPM]":"1.8","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"1.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"136.1","Brain RNA - basal ganglia [nTPM]":"206.6","Brain RNA - cerebellum [nTPM]":"194.2","Brain RNA - cerebral cortex [nTPM]":"243.3","Brain RNA - hippocampal formation [nTPM]":"142.9","Brain RNA - hypothalamus [nTPM]":"159.9","Brain RNA - medulla oblongata [nTPM]":"212.0","Brain RNA - midbrain [nTPM]":"194.9","Brain RNA - pons [nTPM]":"212.1","Brain RNA - spinal cord [nTPM]":"155.2","Brain RNA - thalamus [nTPM]":"187.8","Brain RNA - white matter [nTPM]":"279.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"34.5","Single Cell Type RNA - Astrocytes [nTPM]":"16.0","Single Cell Type RNA - B-cells [nTPM]":"2.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"2.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"4.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - dendritic cells [nTPM]":"1.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"512.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.6","Single Cell Type RNA - Endothelial cells [nTPM]":"2.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.6","Single Cell Type RNA - Fibroblasts [nTPM]":"1.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"8.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"32.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.8","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.4","Single Cell Type RNA - Langerhans cells [nTPM]":"11.6","Single Cell Type RNA - Late spermatids [nTPM]":"183.6","Single Cell Type RNA - Leydig cells [nTPM]":"5.3","Single Cell Type RNA - Macrophages [nTPM]":"2.9","Single Cell Type RNA - Melanocytes [nTPM]":"482.0","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"2.5","Single Cell Type RNA - Muller glia cells [nTPM]":"3.7","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"220.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"5.4","Single Cell Type RNA - Peritubular cells [nTPM]":"3.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"59.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.6","Single Cell Type RNA - Spermatocytes [nTPM]":"15.9","Single Cell Type RNA - Spermatogonia [nTPM]":"4.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.3","Single Cell Type RNA - T-cells [nTPM]":"1.8","Single Cell Type RNA - Theca cells [nTPM]":"1.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"CAPN5","Gene synonym":["ADNIV","HTRA3","nCL-3","VRNI"],"Ensembl":"ENSG00000149260","Gene description":"Calpain 5","Uniprot":["O15484"],"Chromosome":"11","Position":"77066961-77126155","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"60.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"170.3","Gastric mucus-secreting cells":"80.0","Intestinal goblet cells":"89.8","Paneth cells":"72.6","Proximal enterocytes":"75.6","Undifferentiated cells":"69.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"1.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"T-cells":"1.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"OE19":"106.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033237","HPA072319"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB033237":"AB_2069673","HPA072319":"AB_2686512"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.16e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-3"},"Tissue RNA - adipose tissue [nTPM]":"6.7","Tissue RNA - adrenal gland [nTPM]":"12.2","Tissue RNA - amygdala [nTPM]":"8.5","Tissue RNA - appendix [nTPM]":"10.9","Tissue RNA - basal ganglia [nTPM]":"7.9","Tissue RNA - bone marrow [nTPM]":"2.7","Tissue RNA - breast [nTPM]":"4.9","Tissue RNA - cerebellum [nTPM]":"6.4","Tissue RNA - cerebral cortex [nTPM]":"8.6","Tissue RNA - cervix [nTPM]":"13.5","Tissue RNA - choroid plexus [nTPM]":"3.5","Tissue RNA - colon [nTPM]":"60.5","Tissue RNA - duodenum [nTPM]":"60.7","Tissue RNA - endometrium 1 [nTPM]":"10.0","Tissue RNA - epididymis [nTPM]":"5.7","Tissue RNA - esophagus [nTPM]":"31.6","Tissue RNA - fallopian tube [nTPM]":"10.8","Tissue RNA - gallbladder [nTPM]":"36.3","Tissue RNA - heart muscle [nTPM]":"7.2","Tissue RNA - hippocampal formation [nTPM]":"8.5","Tissue RNA - hypothalamus [nTPM]":"8.7","Tissue RNA - kidney [nTPM]":"15.1","Tissue RNA - liver [nTPM]":"52.1","Tissue RNA - lung [nTPM]":"4.8","Tissue RNA - lymph node [nTPM]":"1.9","Tissue RNA - medulla oblongata [nTPM]":"11.7","Tissue RNA - midbrain [nTPM]":"8.2","Tissue RNA - ovary [nTPM]":"13.2","Tissue RNA - pancreas [nTPM]":"5.6","Tissue RNA - parathyroid gland [nTPM]":"1.0","Tissue RNA - pituitary gland [nTPM]":"5.1","Tissue RNA - placenta [nTPM]":"2.8","Tissue RNA - pons [nTPM]":"12.5","Tissue RNA - prostate [nTPM]":"16.0","Tissue RNA - rectum [nTPM]":"49.9","Tissue RNA - retina [nTPM]":"3.8","Tissue RNA - salivary gland [nTPM]":"7.7","Tissue RNA - seminal vesicle [nTPM]":"8.9","Tissue RNA - skeletal muscle [nTPM]":"1.6","Tissue RNA - skin 1 [nTPM]":"3.1","Tissue RNA - small intestine [nTPM]":"52.4","Tissue RNA - smooth muscle [nTPM]":"11.3","Tissue RNA - spinal cord [nTPM]":"9.9","Tissue RNA - spleen [nTPM]":"3.5","Tissue RNA - stomach 1 [nTPM]":"47.9","Tissue RNA - testis [nTPM]":"21.5","Tissue RNA - thalamus [nTPM]":"7.9","Tissue RNA - thymus [nTPM]":"2.8","Tissue RNA - thyroid gland [nTPM]":"4.7","Tissue RNA - tongue [nTPM]":"1.7","Tissue RNA - tonsil [nTPM]":"2.7","Tissue RNA - urinary bladder [nTPM]":"15.4","Tissue RNA - vagina [nTPM]":"10.5","Tissue RNA - white matter [nTPM]":"8.1","Cell RNA - A-431 [nTPM]":"0.8","Cell RNA - A549 [nTPM]":"12.5","Cell RNA - AF22 [nTPM]":"8.6","Cell RNA - AN3-CA [nTPM]":"7.8","Cell RNA - ASC diff [nTPM]":"32.0","Cell RNA - ASC TERT1 [nTPM]":"30.4","Cell RNA - BEWO [nTPM]":"0.7","Cell RNA - BJ [nTPM]":"11.8","Cell RNA - BJ hTERT+ [nTPM]":"22.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.0","Cell RNA - CACO-2 [nTPM]":"6.9","Cell RNA - CAPAN-2 [nTPM]":"3.6","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"7.7","Cell RNA - fHDF\/TERT166 [nTPM]":"24.5","Cell RNA - GAMG [nTPM]":"14.4","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"3.8","Cell RNA - HBEC3-KT [nTPM]":"1.0","Cell RNA - HBF TERT88 [nTPM]":"6.4","Cell RNA - HDLM-2 [nTPM]":"0.5","Cell RNA - HEK 293 [nTPM]":"0.8","Cell RNA - HEL [nTPM]":"2.1","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"0.9","Cell RNA - HHSteC [nTPM]":"7.9","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"16.1","Cell RNA - hTCEpi [nTPM]":"1.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.6","Cell RNA - hTERT-HME1 [nTPM]":"5.2","Cell RNA - hTERT-RPE1 [nTPM]":"18.8","Cell RNA - HUVEC TERT2 [nTPM]":"14.4","Cell RNA - JURKAT [nTPM]":"5.1","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"26.9","Cell RNA - MCF7 [nTPM]":"19.9","Cell RNA - MOLT-4 [nTPM]":"1.8","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"6.6","Cell RNA - OE19 [nTPM]":"106.6","Cell RNA - PC-3 [nTPM]":"9.3","Cell RNA - REH [nTPM]":"2.0","Cell RNA - RH-30 [nTPM]":"27.0","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"4.6","Cell RNA - RT4 [nTPM]":"16.4","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"13.5","Cell RNA - SiHa [nTPM]":"1.0","Cell RNA - SK-BR-3 [nTPM]":"2.7","Cell RNA - SK-MEL-30 [nTPM]":"5.9","Cell RNA - SuSa [nTPM]":"5.7","Cell RNA - T-47d [nTPM]":"1.7","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"23.9","Cell RNA - U-138 MG [nTPM]":"25.4","Cell RNA - U-2 OS [nTPM]":"12.3","Cell RNA - U-2197 [nTPM]":"34.8","Cell RNA - U-251 MG [nTPM]":"1.3","Cell RNA - U-266\/70 [nTPM]":"0.8","Cell RNA - U-266\/84 [nTPM]":"1.7","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"13.1","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"5.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.3","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.8","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"8.5","Brain RNA - basal ganglia [nTPM]":"7.9","Brain RNA - cerebellum [nTPM]":"6.4","Brain RNA - cerebral cortex [nTPM]":"8.6","Brain RNA - hippocampal formation [nTPM]":"8.5","Brain RNA - hypothalamus [nTPM]":"8.7","Brain RNA - medulla oblongata [nTPM]":"11.7","Brain RNA - midbrain [nTPM]":"8.2","Brain RNA - pons [nTPM]":"12.5","Brain RNA - spinal cord [nTPM]":"9.9","Brain RNA - thalamus [nTPM]":"7.9","Brain RNA - white matter [nTPM]":"8.1","Single Cell Type RNA - Adipocytes [nTPM]":"1.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"4.2","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"3.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"10.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"3.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"170.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"10.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.9","Single Cell Type RNA - Endothelial cells [nTPM]":"2.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.3","Single Cell Type RNA - Erythroid cells [nTPM]":"5.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"32.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"7.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"80.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"10.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.9","Single Cell Type RNA - Hepatocytes [nTPM]":"40.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.9","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"89.8","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"1.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"12.5","Single Cell Type RNA - Macrophages [nTPM]":"1.2","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.3","Single Cell Type RNA - Muller glia cells [nTPM]":"5.8","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.4","Single Cell Type RNA - Paneth cells [nTPM]":"72.6","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"0.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"75.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"2.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.5","Single Cell Type RNA - Theca cells [nTPM]":"5.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"69.2","Single Cell Type RNA - Urothelial cells [nTPM]":"2.4"},{"Gene":"CARS1","Gene synonym":["CARS"],"Ensembl":"ENSG00000110619","Gene description":"Cysteinyl-tRNA synthetase 1","Uniprot":["P49589"],"Chromosome":"11","Position":"3000922-3057613","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Cancer-related genes","Disease variant","Dwarfism","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"10.3","Cardiomyocytes":"8.8","Cytotrophoblasts":"22.2","Extravillous trophoblasts":"40.7","Hofbauer cells":"22.0","Syncytiotrophoblasts":"32.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002383","HPA002384","CAB075734","CAB075735","CAB075736","CAB075737"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"200000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB075734":"AB_2665740","CAB075735":"AB_2665741","CAB075736":"AB_2665742","CAB075737":"AB_2665743","HPA002383":"AB_1078399","HPA002384":"AB_1846033"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.16e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Tissue RNA - adipose tissue [nTPM]":"22.1","Tissue RNA - adrenal gland [nTPM]":"17.4","Tissue RNA - amygdala [nTPM]":"8.1","Tissue RNA - appendix [nTPM]":"12.0","Tissue RNA - basal ganglia [nTPM]":"8.5","Tissue RNA - bone marrow [nTPM]":"7.3","Tissue RNA - breast [nTPM]":"19.9","Tissue RNA - cerebellum [nTPM]":"8.7","Tissue RNA - cerebral cortex [nTPM]":"21.6","Tissue RNA - cervix [nTPM]":"13.6","Tissue RNA - choroid plexus [nTPM]":"8.4","Tissue RNA - colon [nTPM]":"21.8","Tissue RNA - duodenum [nTPM]":"12.0","Tissue RNA - endometrium 1 [nTPM]":"15.9","Tissue RNA - epididymis [nTPM]":"7.5","Tissue RNA - esophagus [nTPM]":"19.2","Tissue RNA - fallopian tube [nTPM]":"12.8","Tissue RNA - gallbladder [nTPM]":"10.3","Tissue RNA - heart muscle [nTPM]":"13.3","Tissue RNA - hippocampal formation [nTPM]":"8.2","Tissue RNA - hypothalamus [nTPM]":"9.8","Tissue RNA - kidney [nTPM]":"13.7","Tissue RNA - liver [nTPM]":"21.1","Tissue RNA - lung [nTPM]":"17.5","Tissue RNA - lymph node [nTPM]":"12.7","Tissue RNA - medulla oblongata [nTPM]":"9.6","Tissue RNA - midbrain [nTPM]":"9.9","Tissue RNA - ovary [nTPM]":"8.9","Tissue RNA - pancreas [nTPM]":"32.8","Tissue RNA - parathyroid gland [nTPM]":"9.6","Tissue RNA - pituitary gland [nTPM]":"18.6","Tissue RNA - placenta [nTPM]":"10.3","Tissue RNA - pons [nTPM]":"10.6","Tissue RNA - prostate [nTPM]":"12.7","Tissue RNA - rectum [nTPM]":"12.8","Tissue RNA - retina [nTPM]":"5.3","Tissue RNA - salivary gland [nTPM]":"20.6","Tissue RNA - seminal vesicle [nTPM]":"6.8","Tissue RNA - skeletal muscle [nTPM]":"31.7","Tissue RNA - skin 1 [nTPM]":"23.8","Tissue RNA - small intestine [nTPM]":"17.4","Tissue RNA - smooth muscle [nTPM]":"16.0","Tissue RNA - spinal cord [nTPM]":"9.7","Tissue RNA - spleen [nTPM]":"17.2","Tissue RNA - stomach 1 [nTPM]":"23.5","Tissue RNA - testis [nTPM]":"16.8","Tissue RNA - thalamus [nTPM]":"9.9","Tissue RNA - thymus [nTPM]":"14.6","Tissue RNA - thyroid gland [nTPM]":"17.3","Tissue RNA - tongue [nTPM]":"14.7","Tissue RNA - tonsil [nTPM]":"17.8","Tissue RNA - urinary bladder [nTPM]":"18.1","Tissue RNA - vagina [nTPM]":"14.9","Tissue RNA - white matter [nTPM]":"11.5","Cell RNA - A-431 [nTPM]":"29.2","Cell RNA - A549 [nTPM]":"14.0","Cell RNA - AF22 [nTPM]":"17.8","Cell RNA - AN3-CA [nTPM]":"55.6","Cell RNA - ASC diff [nTPM]":"67.3","Cell RNA - ASC TERT1 [nTPM]":"61.4","Cell RNA - BEWO [nTPM]":"16.2","Cell RNA - BJ [nTPM]":"70.0","Cell RNA - BJ hTERT+ [nTPM]":"78.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"46.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"84.1","Cell RNA - CACO-2 [nTPM]":"34.2","Cell RNA - CAPAN-2 [nTPM]":"64.7","Cell RNA - Daudi [nTPM]":"43.1","Cell RNA - EFO-21 [nTPM]":"20.1","Cell RNA - fHDF\/TERT166 [nTPM]":"88.2","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"68.7","Cell RNA - HAP1 [nTPM]":"58.3","Cell RNA - HBEC3-KT [nTPM]":"78.6","Cell RNA - HBF TERT88 [nTPM]":"64.0","Cell RNA - HDLM-2 [nTPM]":"123.7","Cell RNA - HEK 293 [nTPM]":"13.5","Cell RNA - HEL [nTPM]":"24.4","Cell RNA - HeLa [nTPM]":"23.7","Cell RNA - Hep G2 [nTPM]":"25.8","Cell RNA - HHSteC [nTPM]":"161.1","Cell RNA - HL-60 [nTPM]":"50.9","Cell RNA - HMC-1 [nTPM]":"50.2","Cell RNA - HSkMC [nTPM]":"102.2","Cell RNA - hTCEpi [nTPM]":"64.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"40.1","Cell RNA - hTERT-HME1 [nTPM]":"46.8","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"62.3","Cell RNA - JURKAT [nTPM]":"103.6","Cell RNA - K-562 [nTPM]":"42.2","Cell RNA - Karpas-707 [nTPM]":"147.0","Cell RNA - LHCN-M2 [nTPM]":"47.1","Cell RNA - MCF7 [nTPM]":"41.9","Cell RNA - MOLT-4 [nTPM]":"35.7","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"65.2","Cell RNA - OE19 [nTPM]":"97.9","Cell RNA - PC-3 [nTPM]":"25.0","Cell RNA - REH [nTPM]":"17.2","Cell RNA - RH-30 [nTPM]":"29.7","Cell RNA - RPMI-8226 [nTPM]":"54.9","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"46.1","Cell RNA - SCLC-21H [nTPM]":"39.0","Cell RNA - SH-SY5Y [nTPM]":"49.7","Cell RNA - SiHa [nTPM]":"17.1","Cell RNA - SK-BR-3 [nTPM]":"48.1","Cell RNA - SK-MEL-30 [nTPM]":"80.1","Cell RNA - SuSa [nTPM]":"13.3","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"21.8","Cell RNA - U-138 MG [nTPM]":"19.5","Cell RNA - U-2 OS [nTPM]":"18.2","Cell RNA - U-2197 [nTPM]":"48.2","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"107.8","Cell RNA - U-266\/84 [nTPM]":"106.8","Cell RNA - U-698 [nTPM]":"27.2","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"26.6","Cell RNA - WM-115 [nTPM]":"40.3","Blood RNA - basophil [nTPM]":"16.3","Blood RNA - classical monocyte [nTPM]":"18.6","Blood RNA - eosinophil [nTPM]":"13.5","Blood RNA - gdT-cell [nTPM]":"20.9","Blood RNA - intermediate monocyte [nTPM]":"15.4","Blood RNA - MAIT T-cell [nTPM]":"17.4","Blood RNA - memory B-cell [nTPM]":"10.9","Blood RNA - memory CD4 T-cell [nTPM]":"18.3","Blood RNA - memory CD8 T-cell [nTPM]":"18.6","Blood RNA - myeloid DC [nTPM]":"19.4","Blood RNA - naive B-cell [nTPM]":"8.5","Blood RNA - naive CD4 T-cell [nTPM]":"9.9","Blood RNA - naive CD8 T-cell [nTPM]":"16.0","Blood RNA - neutrophil [nTPM]":"25.4","Blood RNA - NK-cell [nTPM]":"23.7","Blood RNA - non-classical monocyte [nTPM]":"37.9","Blood RNA - plasmacytoid DC [nTPM]":"7.5","Blood RNA - T-reg [nTPM]":"27.0","Blood RNA - total PBMC [nTPM]":"19.2","Brain RNA - amygdala [nTPM]":"8.1","Brain RNA - basal ganglia [nTPM]":"8.5","Brain RNA - cerebellum [nTPM]":"8.7","Brain RNA - cerebral cortex [nTPM]":"21.6","Brain RNA - hippocampal formation [nTPM]":"8.2","Brain RNA - hypothalamus [nTPM]":"9.8","Brain RNA - medulla oblongata [nTPM]":"9.6","Brain RNA - midbrain [nTPM]":"9.9","Brain RNA - pons [nTPM]":"10.6","Brain RNA - spinal cord [nTPM]":"9.7","Brain RNA - thalamus [nTPM]":"9.9","Brain RNA - white matter [nTPM]":"11.5","Single Cell Type RNA - Adipocytes [nTPM]":"10.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"22.2","Single Cell Type RNA - dendritic cells [nTPM]":"8.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"2.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"40.7","Single Cell Type RNA - Fibroblasts [nTPM]":"3.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"3.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"32.3","Single Cell Type RNA - T-cells [nTPM]":"1.4","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CARS2","Gene synonym":["FLJ12118"],"Ensembl":"ENSG00000134905","Gene description":"Cysteinyl-tRNA synthetase 2, mitochondrial","Uniprot":["Q9HA77"],"Chromosome":"13","Position":"110641412-110713603","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"221.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-87 MG":"204.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041776"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA041776":"AB_2677666"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.84e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.21e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.49e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Tissue RNA - adipose tissue [nTPM]":"18.3","Tissue RNA - adrenal gland [nTPM]":"24.4","Tissue RNA - amygdala [nTPM]":"8.8","Tissue RNA - appendix [nTPM]":"18.9","Tissue RNA - basal ganglia [nTPM]":"9.3","Tissue RNA - bone marrow [nTPM]":"28.4","Tissue RNA - breast [nTPM]":"15.0","Tissue RNA - cerebellum [nTPM]":"16.3","Tissue RNA - cerebral cortex [nTPM]":"13.3","Tissue RNA - cervix [nTPM]":"20.3","Tissue RNA - choroid plexus [nTPM]":"15.8","Tissue RNA - colon [nTPM]":"20.8","Tissue RNA - duodenum [nTPM]":"17.5","Tissue RNA - endometrium 1 [nTPM]":"16.0","Tissue RNA - epididymis [nTPM]":"13.7","Tissue RNA - esophagus [nTPM]":"18.6","Tissue RNA - fallopian tube [nTPM]":"16.4","Tissue RNA - gallbladder [nTPM]":"11.1","Tissue RNA - heart muscle [nTPM]":"25.9","Tissue RNA - hippocampal formation [nTPM]":"9.7","Tissue RNA - hypothalamus [nTPM]":"9.3","Tissue RNA - kidney [nTPM]":"15.4","Tissue RNA - liver [nTPM]":"19.9","Tissue RNA - lung [nTPM]":"16.7","Tissue RNA - lymph node [nTPM]":"19.3","Tissue RNA - medulla oblongata [nTPM]":"9.0","Tissue RNA - midbrain [nTPM]":"9.3","Tissue RNA - ovary [nTPM]":"15.3","Tissue RNA - pancreas [nTPM]":"15.8","Tissue RNA - parathyroid gland [nTPM]":"15.0","Tissue RNA - pituitary gland [nTPM]":"17.6","Tissue RNA - placenta [nTPM]":"12.1","Tissue RNA - pons [nTPM]":"9.7","Tissue RNA - prostate [nTPM]":"15.2","Tissue RNA - rectum [nTPM]":"13.8","Tissue RNA - retina [nTPM]":"9.2","Tissue RNA - salivary gland [nTPM]":"18.9","Tissue RNA - seminal vesicle [nTPM]":"12.3","Tissue RNA - skeletal muscle [nTPM]":"45.8","Tissue RNA - skin 1 [nTPM]":"17.6","Tissue RNA - small intestine [nTPM]":"18.5","Tissue RNA - smooth muscle [nTPM]":"12.6","Tissue RNA - spinal cord [nTPM]":"9.2","Tissue RNA - spleen [nTPM]":"17.8","Tissue RNA - stomach 1 [nTPM]":"17.2","Tissue RNA - testis [nTPM]":"11.2","Tissue RNA - thalamus [nTPM]":"9.7","Tissue RNA - thymus [nTPM]":"12.9","Tissue RNA - thyroid gland [nTPM]":"14.3","Tissue RNA - tongue [nTPM]":"26.7","Tissue RNA - tonsil [nTPM]":"14.1","Tissue RNA - urinary bladder [nTPM]":"17.7","Tissue RNA - vagina [nTPM]":"15.9","Tissue RNA - white matter [nTPM]":"10.5","Cell RNA - A-431 [nTPM]":"116.0","Cell RNA - A549 [nTPM]":"37.7","Cell RNA - AF22 [nTPM]":"21.2","Cell RNA - AN3-CA [nTPM]":"52.6","Cell RNA - ASC diff [nTPM]":"55.7","Cell RNA - ASC TERT1 [nTPM]":"51.7","Cell RNA - BEWO [nTPM]":"28.7","Cell RNA - BJ [nTPM]":"49.9","Cell RNA - BJ hTERT+ [nTPM]":"45.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"49.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"60.6","Cell RNA - CACO-2 [nTPM]":"53.5","Cell RNA - CAPAN-2 [nTPM]":"50.7","Cell RNA - Daudi [nTPM]":"53.5","Cell RNA - EFO-21 [nTPM]":"68.4","Cell RNA - fHDF\/TERT166 [nTPM]":"55.4","Cell RNA - GAMG [nTPM]":"75.6","Cell RNA - HaCaT [nTPM]":"61.0","Cell RNA - HAP1 [nTPM]":"36.6","Cell RNA - HBEC3-KT [nTPM]":"63.8","Cell RNA - HBF TERT88 [nTPM]":"40.2","Cell RNA - HDLM-2 [nTPM]":"49.2","Cell RNA - HEK 293 [nTPM]":"58.5","Cell RNA - HEL [nTPM]":"33.5","Cell RNA - HeLa [nTPM]":"79.6","Cell RNA - Hep G2 [nTPM]":"63.8","Cell RNA - HHSteC [nTPM]":"58.5","Cell RNA - HL-60 [nTPM]":"83.0","Cell RNA - HMC-1 [nTPM]":"39.3","Cell RNA - HSkMC [nTPM]":"66.7","Cell RNA - hTCEpi [nTPM]":"50.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"43.3","Cell RNA - hTERT-HME1 [nTPM]":"51.8","Cell RNA - hTERT-RPE1 [nTPM]":"35.5","Cell RNA - HUVEC TERT2 [nTPM]":"36.0","Cell RNA - JURKAT [nTPM]":"40.9","Cell RNA - K-562 [nTPM]":"23.2","Cell RNA - Karpas-707 [nTPM]":"16.6","Cell RNA - LHCN-M2 [nTPM]":"71.2","Cell RNA - MCF7 [nTPM]":"27.2","Cell RNA - MOLT-4 [nTPM]":"37.5","Cell RNA - NB-4 [nTPM]":"27.6","Cell RNA - NTERA-2 [nTPM]":"18.4","Cell RNA - OE19 [nTPM]":"88.9","Cell RNA - PC-3 [nTPM]":"36.8","Cell RNA - REH [nTPM]":"54.2","Cell RNA - RH-30 [nTPM]":"15.6","Cell RNA - RPMI-8226 [nTPM]":"22.3","Cell RNA - RPTEC TERT1 [nTPM]":"54.2","Cell RNA - RT4 [nTPM]":"33.4","Cell RNA - SCLC-21H [nTPM]":"37.7","Cell RNA - SH-SY5Y [nTPM]":"28.9","Cell RNA - SiHa [nTPM]":"40.7","Cell RNA - SK-BR-3 [nTPM]":"62.0","Cell RNA - SK-MEL-30 [nTPM]":"61.1","Cell RNA - SuSa [nTPM]":"22.7","Cell RNA - T-47d [nTPM]":"29.8","Cell RNA - THP-1 [nTPM]":"94.0","Cell RNA - TIME [nTPM]":"32.5","Cell RNA - U-138 MG [nTPM]":"41.8","Cell RNA - U-2 OS [nTPM]":"15.6","Cell RNA - U-2197 [nTPM]":"53.2","Cell RNA - U-251 MG [nTPM]":"51.6","Cell RNA - U-266\/70 [nTPM]":"29.0","Cell RNA - U-266\/84 [nTPM]":"35.8","Cell RNA - U-698 [nTPM]":"32.4","Cell RNA - U-87 MG [nTPM]":"204.5","Cell RNA - U-937 [nTPM]":"50.1","Cell RNA - WM-115 [nTPM]":"41.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.9","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"1.1","Blood RNA - intermediate monocyte [nTPM]":"3.3","Blood RNA - MAIT T-cell [nTPM]":"1.2","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"2.4","Blood RNA - naive B-cell [nTPM]":"0.8","Blood RNA - naive CD4 T-cell [nTPM]":"1.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"1.7","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"4.6","Blood RNA - plasmacytoid DC [nTPM]":"2.0","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"8.8","Brain RNA - basal ganglia [nTPM]":"9.3","Brain RNA - cerebellum [nTPM]":"16.3","Brain RNA - cerebral cortex [nTPM]":"13.3","Brain RNA - hippocampal formation [nTPM]":"9.7","Brain RNA - hypothalamus [nTPM]":"9.3","Brain RNA - medulla oblongata [nTPM]":"9.0","Brain RNA - midbrain [nTPM]":"9.3","Brain RNA - pons [nTPM]":"9.7","Brain RNA - spinal cord [nTPM]":"9.2","Brain RNA - thalamus [nTPM]":"9.7","Brain RNA - white matter [nTPM]":"10.5","Single Cell Type RNA - Adipocytes [nTPM]":"18.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.9","Single Cell Type RNA - Astrocytes [nTPM]":"24.5","Single Cell Type RNA - B-cells [nTPM]":"24.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"21.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"39.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"9.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"26.7","Single Cell Type RNA - dendritic cells [nTPM]":"28.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"50.9","Single Cell Type RNA - Ductal cells [nTPM]":"17.7","Single Cell Type RNA - Early spermatids [nTPM]":"66.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"24.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.7","Single Cell Type RNA - Endothelial cells [nTPM]":"13.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.7","Single Cell Type RNA - Erythroid cells [nTPM]":"10.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"29.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"29.1","Single Cell Type RNA - Fibroblasts [nTPM]":"21.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"27.3","Single Cell Type RNA - granulocytes [nTPM]":"16.5","Single Cell Type RNA - Granulosa cells [nTPM]":"45.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.3","Single Cell Type RNA - Hepatocytes [nTPM]":"26.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"26.9","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.7","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"31.2","Single Cell Type RNA - Langerhans cells [nTPM]":"9.0","Single Cell Type RNA - Late spermatids [nTPM]":"221.4","Single Cell Type RNA - Leydig cells [nTPM]":"20.5","Single Cell Type RNA - Macrophages [nTPM]":"32.8","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"24.4","Single Cell Type RNA - monocytes [nTPM]":"51.4","Single Cell Type RNA - Muller glia cells [nTPM]":"24.3","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"26.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.1","Single Cell Type RNA - Paneth cells [nTPM]":"10.8","Single Cell Type RNA - Peritubular cells [nTPM]":"18.0","Single Cell Type RNA - Plasma cells [nTPM]":"18.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"38.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"25.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"29.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"24.7","Single Cell Type RNA - Spermatocytes [nTPM]":"8.6","Single Cell Type RNA - Spermatogonia [nTPM]":"7.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.8","Single Cell Type RNA - T-cells [nTPM]":"19.8","Single Cell Type RNA - Theca cells [nTPM]":"44.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"28.5","Single Cell Type RNA - Urothelial cells [nTPM]":"17.6"},{"Gene":"CASK","Gene synonym":["CAGH39","FGS4","LIN2","TNRC8"],"Ensembl":"ENSG00000147044","Gene description":"Calcium\/calmodulin dependent serine protein kinase","Uniprot":["O14936"],"Chromosome":"X","Position":"41514934-41923554","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Calmodulin-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"135.8","Oligodendrocyte precursor cells":"447.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"47.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"granulocytes":"47.1"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB001949","HPA023857"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB001949":null,"HPA023857":"AB_1846035"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.11e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.2","Tissue RNA - adrenal gland [nTPM]":"11.1","Tissue RNA - amygdala [nTPM]":"13.6","Tissue RNA - appendix [nTPM]":"11.9","Tissue RNA - basal ganglia [nTPM]":"12.9","Tissue RNA - bone marrow [nTPM]":"7.3","Tissue RNA - breast [nTPM]":"15.7","Tissue RNA - cerebellum [nTPM]":"12.3","Tissue RNA - cerebral cortex [nTPM]":"11.1","Tissue RNA - cervix [nTPM]":"11.6","Tissue RNA - choroid plexus [nTPM]":"12.4","Tissue RNA - colon [nTPM]":"25.3","Tissue RNA - duodenum [nTPM]":"32.1","Tissue RNA - endometrium 1 [nTPM]":"11.1","Tissue RNA - epididymis [nTPM]":"9.4","Tissue RNA - esophagus [nTPM]":"13.7","Tissue RNA - fallopian tube [nTPM]":"10.5","Tissue RNA - gallbladder [nTPM]":"18.5","Tissue RNA - heart muscle [nTPM]":"6.8","Tissue RNA - hippocampal formation [nTPM]":"14.2","Tissue RNA - hypothalamus [nTPM]":"17.1","Tissue RNA - kidney [nTPM]":"16.4","Tissue RNA - liver [nTPM]":"13.4","Tissue RNA - lung [nTPM]":"12.2","Tissue RNA - lymph node [nTPM]":"12.5","Tissue RNA - medulla oblongata [nTPM]":"13.2","Tissue RNA - midbrain [nTPM]":"19.4","Tissue RNA - ovary [nTPM]":"13.5","Tissue RNA - pancreas [nTPM]":"12.8","Tissue RNA - parathyroid gland [nTPM]":"11.8","Tissue RNA - pituitary gland [nTPM]":"6.3","Tissue RNA - placenta [nTPM]":"16.3","Tissue RNA - pons [nTPM]":"15.7","Tissue RNA - prostate [nTPM]":"10.6","Tissue RNA - rectum [nTPM]":"27.3","Tissue RNA - retina [nTPM]":"19.8","Tissue RNA - salivary gland [nTPM]":"13.2","Tissue RNA - seminal vesicle [nTPM]":"8.3","Tissue RNA - skeletal muscle [nTPM]":"5.0","Tissue RNA - skin 1 [nTPM]":"9.3","Tissue RNA - small intestine [nTPM]":"31.9","Tissue RNA - smooth muscle [nTPM]":"12.0","Tissue RNA - spinal cord [nTPM]":"15.4","Tissue RNA - spleen [nTPM]":"12.4","Tissue RNA - stomach 1 [nTPM]":"19.8","Tissue RNA - testis [nTPM]":"3.6","Tissue RNA - thalamus [nTPM]":"25.2","Tissue RNA - thymus [nTPM]":"15.4","Tissue RNA - thyroid gland [nTPM]":"10.6","Tissue RNA - tongue [nTPM]":"6.1","Tissue RNA - tonsil [nTPM]":"10.4","Tissue RNA - urinary bladder [nTPM]":"15.3","Tissue RNA - vagina [nTPM]":"8.8","Tissue RNA - white matter [nTPM]":"18.0","Cell RNA - A-431 [nTPM]":"27.4","Cell RNA - A549 [nTPM]":"32.5","Cell RNA - AF22 [nTPM]":"31.4","Cell RNA - AN3-CA [nTPM]":"19.1","Cell RNA - ASC diff [nTPM]":"21.6","Cell RNA - ASC TERT1 [nTPM]":"18.6","Cell RNA - BEWO [nTPM]":"10.9","Cell RNA - BJ [nTPM]":"23.2","Cell RNA - BJ hTERT+ [nTPM]":"18.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.3","Cell RNA - CACO-2 [nTPM]":"72.3","Cell RNA - CAPAN-2 [nTPM]":"42.6","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"12.0","Cell RNA - fHDF\/TERT166 [nTPM]":"29.3","Cell RNA - GAMG [nTPM]":"23.8","Cell RNA - HaCaT [nTPM]":"52.3","Cell RNA - HAP1 [nTPM]":"35.2","Cell RNA - HBEC3-KT [nTPM]":"23.2","Cell RNA - HBF TERT88 [nTPM]":"22.8","Cell RNA - HDLM-2 [nTPM]":"25.4","Cell RNA - HEK 293 [nTPM]":"20.9","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"27.7","Cell RNA - Hep G2 [nTPM]":"26.2","Cell RNA - HHSteC [nTPM]":"22.1","Cell RNA - HL-60 [nTPM]":"4.4","Cell RNA - HMC-1 [nTPM]":"3.6","Cell RNA - HSkMC [nTPM]":"19.8","Cell RNA - hTCEpi [nTPM]":"63.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.1","Cell RNA - hTERT-HME1 [nTPM]":"30.1","Cell RNA - hTERT-RPE1 [nTPM]":"27.5","Cell RNA - HUVEC TERT2 [nTPM]":"11.6","Cell RNA - JURKAT [nTPM]":"15.3","Cell RNA - K-562 [nTPM]":"2.2","Cell RNA - Karpas-707 [nTPM]":"21.3","Cell RNA - LHCN-M2 [nTPM]":"30.2","Cell RNA - MCF7 [nTPM]":"30.9","Cell RNA - MOLT-4 [nTPM]":"8.4","Cell RNA - NB-4 [nTPM]":"2.2","Cell RNA - NTERA-2 [nTPM]":"29.7","Cell RNA - OE19 [nTPM]":"37.6","Cell RNA - PC-3 [nTPM]":"22.6","Cell RNA - REH [nTPM]":"12.7","Cell RNA - RH-30 [nTPM]":"79.8","Cell RNA - RPMI-8226 [nTPM]":"13.2","Cell RNA - RPTEC TERT1 [nTPM]":"31.2","Cell RNA - RT4 [nTPM]":"54.8","Cell RNA - SCLC-21H [nTPM]":"29.7","Cell RNA - SH-SY5Y [nTPM]":"15.6","Cell RNA - SiHa [nTPM]":"43.7","Cell RNA - SK-BR-3 [nTPM]":"17.7","Cell RNA - SK-MEL-30 [nTPM]":"13.9","Cell RNA - SuSa [nTPM]":"52.7","Cell RNA - T-47d [nTPM]":"19.0","Cell RNA - THP-1 [nTPM]":"0.8","Cell RNA - TIME [nTPM]":"14.2","Cell RNA - U-138 MG [nTPM]":"24.4","Cell RNA - U-2 OS [nTPM]":"25.8","Cell RNA - U-2197 [nTPM]":"22.1","Cell RNA - U-251 MG [nTPM]":"13.3","Cell RNA - U-266\/70 [nTPM]":"7.6","Cell RNA - U-266\/84 [nTPM]":"5.2","Cell RNA - U-698 [nTPM]":"9.5","Cell RNA - U-87 MG [nTPM]":"24.4","Cell RNA - U-937 [nTPM]":"3.1","Cell RNA - WM-115 [nTPM]":"16.9","Blood RNA - basophil [nTPM]":"47.1","Blood RNA - classical monocyte [nTPM]":"1.5","Blood RNA - eosinophil [nTPM]":"8.7","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.3","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"0.9","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"1.1","Blood RNA - neutrophil [nTPM]":"1.7","Blood RNA - NK-cell [nTPM]":"4.3","Blood RNA - non-classical monocyte [nTPM]":"0.7","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"4.5","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"13.6","Brain RNA - basal ganglia [nTPM]":"12.9","Brain RNA - cerebellum [nTPM]":"12.3","Brain RNA - cerebral cortex [nTPM]":"11.1","Brain RNA - hippocampal formation [nTPM]":"14.2","Brain RNA - hypothalamus [nTPM]":"17.1","Brain RNA - medulla oblongata [nTPM]":"13.2","Brain RNA - midbrain [nTPM]":"19.4","Brain RNA - pons [nTPM]":"15.7","Brain RNA - spinal cord [nTPM]":"15.4","Brain RNA - thalamus [nTPM]":"25.2","Brain RNA - white matter [nTPM]":"18.0","Single Cell Type RNA - Adipocytes [nTPM]":"13.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.4","Single Cell Type RNA - Astrocytes [nTPM]":"101.9","Single Cell Type RNA - B-cells [nTPM]":"8.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"32.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"42.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"42.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"14.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.0","Single Cell Type RNA - dendritic cells [nTPM]":"12.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"25.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"50.9","Single Cell Type RNA - Ductal cells [nTPM]":"13.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"24.1","Single Cell Type RNA - Endothelial cells [nTPM]":"16.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"96.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"18.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"17.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.9","Single Cell Type RNA - Hepatocytes [nTPM]":"15.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"21.3","Single Cell Type RNA - Horizontal cells [nTPM]":"50.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"135.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.7","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"2.8","Single Cell Type RNA - Langerhans cells [nTPM]":"21.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"9.9","Single Cell Type RNA - Macrophages [nTPM]":"10.7","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"60.0","Single Cell Type RNA - monocytes [nTPM]":"2.5","Single Cell Type RNA - Muller glia cells [nTPM]":"9.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"447.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"59.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.1","Single Cell Type RNA - Paneth cells [nTPM]":"24.1","Single Cell Type RNA - Peritubular cells [nTPM]":"9.4","Single Cell Type RNA - Plasma cells [nTPM]":"7.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"35.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"20.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"25.7","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"38.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.6","Single Cell Type RNA - Spermatocytes [nTPM]":"2.9","Single Cell Type RNA - Spermatogonia [nTPM]":"2.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"32.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.6","Single Cell Type RNA - T-cells [nTPM]":"26.5","Single Cell Type RNA - Theca cells [nTPM]":"47.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"41.8","Single Cell Type RNA - Urothelial cells [nTPM]":"33.2"},{"Gene":"CASP10","Gene synonym":["FLICE-2","MCH4"],"Ensembl":"ENSG00000003400","Gene description":"Caspase 10","Uniprot":["Q92851"],"Chromosome":"2","Position":"201182898-201229406","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"71.3","NK-cells":"44.3","Paneth cells":"44.5","Plasma cells":"49.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HUVEC TERT2":"25.3"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003780","HPA017059"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB003780":"AB_289592","HPA017059":"AB_1846040"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.54e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.05e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.8","Tissue RNA - adrenal gland [nTPM]":"2.4","Tissue RNA - amygdala [nTPM]":"5.7","Tissue RNA - appendix [nTPM]":"9.2","Tissue RNA - basal ganglia [nTPM]":"5.5","Tissue RNA - bone marrow [nTPM]":"19.5","Tissue RNA - breast [nTPM]":"6.5","Tissue RNA - cerebellum [nTPM]":"4.5","Tissue RNA - cerebral cortex [nTPM]":"5.8","Tissue RNA - cervix [nTPM]":"4.0","Tissue RNA - choroid plexus [nTPM]":"4.4","Tissue RNA - colon [nTPM]":"13.2","Tissue RNA - duodenum [nTPM]":"21.8","Tissue RNA - endometrium 1 [nTPM]":"3.3","Tissue RNA - epididymis [nTPM]":"6.2","Tissue RNA - esophagus [nTPM]":"8.8","Tissue RNA - fallopian tube [nTPM]":"5.4","Tissue RNA - gallbladder [nTPM]":"7.4","Tissue RNA - heart muscle [nTPM]":"6.7","Tissue RNA - hippocampal formation [nTPM]":"4.7","Tissue RNA - hypothalamus [nTPM]":"5.1","Tissue RNA - kidney [nTPM]":"8.1","Tissue RNA - liver [nTPM]":"6.2","Tissue RNA - lung [nTPM]":"11.5","Tissue RNA - lymph node [nTPM]":"8.9","Tissue RNA - medulla oblongata [nTPM]":"6.0","Tissue RNA - midbrain [nTPM]":"5.0","Tissue RNA - ovary [nTPM]":"1.6","Tissue RNA - pancreas [nTPM]":"4.8","Tissue RNA - parathyroid gland [nTPM]":"2.3","Tissue RNA - pituitary gland [nTPM]":"1.3","Tissue RNA - placenta [nTPM]":"9.6","Tissue RNA - pons [nTPM]":"5.8","Tissue RNA - prostate [nTPM]":"3.9","Tissue RNA - rectum [nTPM]":"13.4","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"5.4","Tissue RNA - seminal vesicle [nTPM]":"3.1","Tissue RNA - skeletal muscle [nTPM]":"4.9","Tissue RNA - skin 1 [nTPM]":"5.7","Tissue RNA - small intestine [nTPM]":"18.4","Tissue RNA - smooth muscle [nTPM]":"5.1","Tissue RNA - spinal cord [nTPM]":"5.6","Tissue RNA - spleen [nTPM]":"22.6","Tissue RNA - stomach 1 [nTPM]":"10.2","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"7.3","Tissue RNA - thymus [nTPM]":"8.7","Tissue RNA - thyroid gland [nTPM]":"5.3","Tissue RNA - tongue [nTPM]":"2.8","Tissue RNA - tonsil [nTPM]":"10.4","Tissue RNA - urinary bladder [nTPM]":"9.0","Tissue RNA - vagina [nTPM]":"5.1","Tissue RNA - white matter [nTPM]":"5.4","Cell RNA - A-431 [nTPM]":"4.4","Cell RNA - A549 [nTPM]":"3.5","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"7.5","Cell RNA - BJ [nTPM]":"0.7","Cell RNA - BJ hTERT+ [nTPM]":"4.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.8","Cell RNA - CACO-2 [nTPM]":"4.6","Cell RNA - CAPAN-2 [nTPM]":"9.8","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"7.0","Cell RNA - fHDF\/TERT166 [nTPM]":"2.5","Cell RNA - GAMG [nTPM]":"1.7","Cell RNA - HaCaT [nTPM]":"2.9","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"2.3","Cell RNA - HBF TERT88 [nTPM]":"1.3","Cell RNA - HDLM-2 [nTPM]":"2.1","Cell RNA - HEK 293 [nTPM]":"4.8","Cell RNA - HEL [nTPM]":"12.2","Cell RNA - HeLa [nTPM]":"4.0","Cell RNA - Hep G2 [nTPM]":"15.1","Cell RNA - HHSteC [nTPM]":"1.6","Cell RNA - HL-60 [nTPM]":"8.3","Cell RNA - HMC-1 [nTPM]":"12.7","Cell RNA - HSkMC [nTPM]":"0.5","Cell RNA - hTCEpi [nTPM]":"2.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.3","Cell RNA - hTERT-HME1 [nTPM]":"0.4","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"25.3","Cell RNA - JURKAT [nTPM]":"5.1","Cell RNA - K-562 [nTPM]":"14.9","Cell RNA - Karpas-707 [nTPM]":"17.4","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"15.9","Cell RNA - NB-4 [nTPM]":"7.8","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"6.0","Cell RNA - PC-3 [nTPM]":"2.4","Cell RNA - REH [nTPM]":"8.8","Cell RNA - RH-30 [nTPM]":"0.5","Cell RNA - RPMI-8226 [nTPM]":"18.4","Cell RNA - RPTEC TERT1 [nTPM]":"8.7","Cell RNA - RT4 [nTPM]":"6.2","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"4.1","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"1.9","Cell RNA - SuSa [nTPM]":"3.0","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"7.8","Cell RNA - TIME [nTPM]":"10.0","Cell RNA - U-138 MG [nTPM]":"0.4","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"3.4","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"18.7","Cell RNA - U-266\/84 [nTPM]":"12.1","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"4.5","Cell RNA - U-937 [nTPM]":"6.3","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"5.9","Blood RNA - classical monocyte [nTPM]":"11.7","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"6.4","Blood RNA - intermediate monocyte [nTPM]":"16.5","Blood RNA - MAIT T-cell [nTPM]":"5.6","Blood RNA - memory B-cell [nTPM]":"8.2","Blood RNA - memory CD4 T-cell [nTPM]":"5.2","Blood RNA - memory CD8 T-cell [nTPM]":"3.6","Blood RNA - myeloid DC [nTPM]":"6.5","Blood RNA - naive B-cell [nTPM]":"7.7","Blood RNA - naive CD4 T-cell [nTPM]":"7.2","Blood RNA - naive CD8 T-cell [nTPM]":"6.4","Blood RNA - neutrophil [nTPM]":"2.1","Blood RNA - NK-cell [nTPM]":"8.5","Blood RNA - non-classical monocyte [nTPM]":"19.3","Blood RNA - plasmacytoid DC [nTPM]":"6.6","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"7.2","Brain RNA - amygdala [nTPM]":"5.7","Brain RNA - basal ganglia [nTPM]":"5.5","Brain RNA - cerebellum [nTPM]":"4.5","Brain RNA - cerebral cortex [nTPM]":"5.8","Brain RNA - hippocampal formation [nTPM]":"4.7","Brain RNA - hypothalamus [nTPM]":"5.1","Brain RNA - medulla oblongata [nTPM]":"6.0","Brain RNA - midbrain [nTPM]":"5.0","Brain RNA - pons [nTPM]":"5.8","Brain RNA - spinal cord [nTPM]":"5.6","Brain RNA - thalamus [nTPM]":"7.3","Brain RNA - white matter [nTPM]":"5.4","Single Cell Type RNA - Adipocytes [nTPM]":"20.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"15.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"9.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - dendritic cells [nTPM]":"20.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"71.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"16.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.4","Single Cell Type RNA - Endothelial cells [nTPM]":"29.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"14.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"4.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"26.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.0","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.4","Single Cell Type RNA - Hepatocytes [nTPM]":"7.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.6","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"26.6","Single Cell Type RNA - Langerhans cells [nTPM]":"17.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"16.2","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"33.7","Single Cell Type RNA - monocytes [nTPM]":"22.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"44.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.6","Single Cell Type RNA - Paneth cells [nTPM]":"44.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"49.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"26.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"24.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"12.9","Single Cell Type RNA - Theca cells [nTPM]":"4.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.4","Single Cell Type RNA - Urothelial cells [nTPM]":"10.3"},{"Gene":"CASP14","Gene synonym":["MGC119078","MGC119079","MICE"],"Ensembl":"ENSG00000105141","Gene description":"Caspase 14","Uniprot":["P31944"],"Chromosome":"19","Position":"15049480-15058293","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Differentiation"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"24","RNA tissue specific nTPM":{"skin 1":"486.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Suprabasal keratinocytes":"96.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"cervical cancer":"62.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"hTCEpi":"49.0"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010059","HPA027062"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3600000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 28: Keratinocytes - Keratinization","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"CAB010059":"AB_626800","HPA027062":"AB_2672101"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-3"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.59e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.96e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.6","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"7.8","Tissue RNA - cerebellum [nTPM]":"0.4","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"3.9","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.6","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"0.8","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"1.1","Tissue RNA - seminal vesicle [nTPM]":"4.2","Tissue RNA - skeletal muscle [nTPM]":"1.4","Tissue RNA - skin 1 [nTPM]":"486.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"19.9","Tissue RNA - white matter [nTPM]":"1.0","Cell RNA - A-431 [nTPM]":"1.1","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.7","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"3.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"6.8","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"49.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.9","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.6","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.4","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"1.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"19.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"2.4","Single Cell Type RNA - Late spermatids [nTPM]":"2.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"96.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"CASP8","Gene synonym":["Casp-8","FLICE","MACH","MCH5"],"Ensembl":"ENSG00000064012","Gene description":"Caspase 8","Uniprot":["Q14790"],"Chromosome":"2","Position":"201233443-201287711","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Host-virus interaction"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"66.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"107.4","NK-cells":"132.8","Plasma cells":"73.4","T-cells":"86.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001302","CAB002047","HPA005688","HPA006191"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB002047":"AB_563465","HPA001302":"AB_1846057","HPA005688":"AB_1846056","HPA006191":"AB_2667535"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.69e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.02e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.25e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.27e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-3"},"Tissue RNA - adipose tissue [nTPM]":"11.5","Tissue RNA - adrenal gland [nTPM]":"10.2","Tissue RNA - amygdala [nTPM]":"1.7","Tissue RNA - appendix [nTPM]":"28.6","Tissue RNA - basal ganglia [nTPM]":"2.0","Tissue RNA - bone marrow [nTPM]":"66.6","Tissue RNA - breast [nTPM]":"13.9","Tissue RNA - cerebellum [nTPM]":"1.3","Tissue RNA - cerebral cortex [nTPM]":"2.1","Tissue RNA - cervix [nTPM]":"9.6","Tissue RNA - choroid plexus [nTPM]":"4.2","Tissue RNA - colon [nTPM]":"16.1","Tissue RNA - duodenum [nTPM]":"20.5","Tissue RNA - endometrium 1 [nTPM]":"8.5","Tissue RNA - epididymis [nTPM]":"13.2","Tissue RNA - esophagus [nTPM]":"12.9","Tissue RNA - fallopian tube [nTPM]":"14.1","Tissue RNA - gallbladder [nTPM]":"13.2","Tissue RNA - heart muscle [nTPM]":"5.2","Tissue RNA - hippocampal formation [nTPM]":"2.1","Tissue RNA - hypothalamus [nTPM]":"1.8","Tissue RNA - kidney [nTPM]":"10.7","Tissue RNA - liver [nTPM]":"14.1","Tissue RNA - lung [nTPM]":"19.6","Tissue RNA - lymph node [nTPM]":"37.7","Tissue RNA - medulla oblongata [nTPM]":"3.4","Tissue RNA - midbrain [nTPM]":"3.0","Tissue RNA - ovary [nTPM]":"7.7","Tissue RNA - pancreas [nTPM]":"7.8","Tissue RNA - parathyroid gland [nTPM]":"2.9","Tissue RNA - pituitary gland [nTPM]":"3.4","Tissue RNA - placenta [nTPM]":"9.9","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"6.9","Tissue RNA - rectum [nTPM]":"17.6","Tissue RNA - retina [nTPM]":"4.6","Tissue RNA - salivary gland [nTPM]":"8.4","Tissue RNA - seminal vesicle [nTPM]":"7.3","Tissue RNA - skeletal muscle [nTPM]":"3.3","Tissue RNA - skin 1 [nTPM]":"12.1","Tissue RNA - small intestine [nTPM]":"26.0","Tissue RNA - smooth muscle [nTPM]":"9.9","Tissue RNA - spinal cord [nTPM]":"2.4","Tissue RNA - spleen [nTPM]":"37.1","Tissue RNA - stomach 1 [nTPM]":"15.9","Tissue RNA - testis [nTPM]":"4.3","Tissue RNA - thalamus [nTPM]":"2.6","Tissue RNA - thymus [nTPM]":"24.4","Tissue RNA - thyroid gland [nTPM]":"7.9","Tissue RNA - tongue [nTPM]":"3.0","Tissue RNA - tonsil [nTPM]":"29.7","Tissue RNA - urinary bladder [nTPM]":"18.0","Tissue RNA - vagina [nTPM]":"8.6","Tissue RNA - white matter [nTPM]":"2.4","Cell RNA - A-431 [nTPM]":"33.6","Cell RNA - A549 [nTPM]":"26.6","Cell RNA - AF22 [nTPM]":"7.7","Cell RNA - AN3-CA [nTPM]":"22.2","Cell RNA - ASC diff [nTPM]":"20.7","Cell RNA - ASC TERT1 [nTPM]":"29.7","Cell RNA - BEWO [nTPM]":"12.0","Cell RNA - BJ [nTPM]":"13.8","Cell RNA - BJ hTERT+ [nTPM]":"13.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"26.2","Cell RNA - CACO-2 [nTPM]":"36.1","Cell RNA - CAPAN-2 [nTPM]":"54.9","Cell RNA - Daudi [nTPM]":"3.7","Cell RNA - EFO-21 [nTPM]":"29.6","Cell RNA - fHDF\/TERT166 [nTPM]":"10.7","Cell RNA - GAMG [nTPM]":"28.7","Cell RNA - HaCaT [nTPM]":"16.2","Cell RNA - HAP1 [nTPM]":"17.2","Cell RNA - HBEC3-KT [nTPM]":"16.1","Cell RNA - HBF TERT88 [nTPM]":"31.3","Cell RNA - HDLM-2 [nTPM]":"21.1","Cell RNA - HEK 293 [nTPM]":"15.4","Cell RNA - HEL [nTPM]":"31.0","Cell RNA - HeLa [nTPM]":"21.9","Cell RNA - Hep G2 [nTPM]":"35.1","Cell RNA - HHSteC [nTPM]":"17.1","Cell RNA - HL-60 [nTPM]":"25.6","Cell RNA - HMC-1 [nTPM]":"33.8","Cell RNA - HSkMC [nTPM]":"25.9","Cell RNA - hTCEpi [nTPM]":"38.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"30.1","Cell RNA - hTERT-HME1 [nTPM]":"23.9","Cell RNA - hTERT-RPE1 [nTPM]":"13.4","Cell RNA - HUVEC TERT2 [nTPM]":"15.1","Cell RNA - JURKAT [nTPM]":"26.9","Cell RNA - K-562 [nTPM]":"28.6","Cell RNA - Karpas-707 [nTPM]":"69.1","Cell RNA - LHCN-M2 [nTPM]":"14.7","Cell RNA - MCF7 [nTPM]":"13.1","Cell RNA - MOLT-4 [nTPM]":"32.1","Cell RNA - NB-4 [nTPM]":"25.9","Cell RNA - NTERA-2 [nTPM]":"12.6","Cell RNA - OE19 [nTPM]":"17.5","Cell RNA - PC-3 [nTPM]":"23.7","Cell RNA - REH [nTPM]":"24.7","Cell RNA - RH-30 [nTPM]":"15.9","Cell RNA - RPMI-8226 [nTPM]":"55.4","Cell RNA - RPTEC TERT1 [nTPM]":"30.8","Cell RNA - RT4 [nTPM]":"35.3","Cell RNA - SCLC-21H [nTPM]":"2.3","Cell RNA - SH-SY5Y [nTPM]":"1.1","Cell RNA - SiHa [nTPM]":"17.9","Cell RNA - SK-BR-3 [nTPM]":"29.8","Cell RNA - SK-MEL-30 [nTPM]":"18.0","Cell RNA - SuSa [nTPM]":"7.0","Cell RNA - T-47d [nTPM]":"8.0","Cell RNA - THP-1 [nTPM]":"19.1","Cell RNA - TIME [nTPM]":"19.6","Cell RNA - U-138 MG [nTPM]":"17.3","Cell RNA - U-2 OS [nTPM]":"18.0","Cell RNA - U-2197 [nTPM]":"9.0","Cell RNA - U-251 MG [nTPM]":"10.9","Cell RNA - U-266\/70 [nTPM]":"63.1","Cell RNA - U-266\/84 [nTPM]":"30.2","Cell RNA - U-698 [nTPM]":"21.2","Cell RNA - U-87 MG [nTPM]":"25.3","Cell RNA - U-937 [nTPM]":"33.1","Cell RNA - WM-115 [nTPM]":"16.6","Blood RNA - basophil [nTPM]":"76.1","Blood RNA - classical monocyte [nTPM]":"39.5","Blood RNA - eosinophil [nTPM]":"77.1","Blood RNA - gdT-cell [nTPM]":"70.7","Blood RNA - intermediate monocyte [nTPM]":"51.2","Blood RNA - MAIT T-cell [nTPM]":"66.0","Blood RNA - memory B-cell [nTPM]":"40.9","Blood RNA - memory CD4 T-cell [nTPM]":"57.8","Blood RNA - memory CD8 T-cell [nTPM]":"75.9","Blood RNA - myeloid DC [nTPM]":"41.6","Blood RNA - naive B-cell [nTPM]":"24.0","Blood RNA - naive CD4 T-cell [nTPM]":"37.0","Blood RNA - naive CD8 T-cell [nTPM]":"47.2","Blood RNA - neutrophil [nTPM]":"153.6","Blood RNA - NK-cell [nTPM]":"70.6","Blood RNA - non-classical monocyte [nTPM]":"51.5","Blood RNA - plasmacytoid DC [nTPM]":"18.6","Blood RNA - T-reg [nTPM]":"75.0","Blood RNA - total PBMC [nTPM]":"40.6","Brain RNA - amygdala [nTPM]":"1.7","Brain RNA - basal ganglia [nTPM]":"2.0","Brain RNA - cerebellum [nTPM]":"1.3","Brain RNA - cerebral cortex [nTPM]":"2.1","Brain RNA - hippocampal formation [nTPM]":"2.1","Brain RNA - hypothalamus [nTPM]":"1.8","Brain RNA - medulla oblongata [nTPM]":"3.4","Brain RNA - midbrain [nTPM]":"3.0","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"2.4","Brain RNA - thalamus [nTPM]":"2.6","Brain RNA - white matter [nTPM]":"2.4","Single Cell Type RNA - Adipocytes [nTPM]":"8.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"50.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"2.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"13.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.5","Single Cell Type RNA - dendritic cells [nTPM]":"107.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"37.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"12.3","Single Cell Type RNA - Early spermatids [nTPM]":"5.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.1","Single Cell Type RNA - Endothelial cells [nTPM]":"10.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"10.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.1","Single Cell Type RNA - Fibroblasts [nTPM]":"9.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"27.2","Single Cell Type RNA - granulocytes [nTPM]":"24.6","Single Cell Type RNA - Granulosa cells [nTPM]":"10.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"11.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.2","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"25.3","Single Cell Type RNA - Langerhans cells [nTPM]":"15.7","Single Cell Type RNA - Late spermatids [nTPM]":"1.9","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"25.0","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"35.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"132.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.2","Single Cell Type RNA - Paneth cells [nTPM]":"30.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"73.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - T-cells [nTPM]":"86.9","Single Cell Type RNA - Theca cells [nTPM]":"10.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.4","Single Cell Type RNA - Urothelial cells [nTPM]":"12.7"},{"Gene":"CASQ1","Gene synonym":["CASQ","PDIB1"],"Ensembl":"ENSG00000143318","Gene description":"Calsequestrin 1","Uniprot":["P31415"],"Chromosome":"1","Position":"160190575-160201886","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":["Muscle protein"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"64","RNA tissue specific nTPM":{"skeletal muscle":"4442.6","tongue":"1892.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cardiomyocytes":"17.6","Rod photoreceptor cells":"25.2","Skeletal myocytes":"20.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"5.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"BEWO":"19.3","HDLM-2":"38.5","RT4":"67.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007845","CAB015170","HPA026823"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"270000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 37: Myocytes - Muscle contraction","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB015170":"AB_2071451","HPA007845":"AB_1078388","HPA026823":"AB_10603557"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.04e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.93e-5"},"Tissue RNA - adipose tissue [nTPM]":"0.9","Tissue RNA - adrenal gland [nTPM]":"0.4","Tissue RNA - amygdala [nTPM]":"5.1","Tissue RNA - appendix [nTPM]":"0.8","Tissue RNA - basal ganglia [nTPM]":"6.0","Tissue RNA - bone marrow [nTPM]":"1.5","Tissue RNA - breast [nTPM]":"1.4","Tissue RNA - cerebellum [nTPM]":"4.9","Tissue RNA - cerebral cortex [nTPM]":"10.0","Tissue RNA - cervix [nTPM]":"0.5","Tissue RNA - choroid plexus [nTPM]":"3.3","Tissue RNA - colon [nTPM]":"3.3","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"1.7","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"43.1","Tissue RNA - fallopian tube [nTPM]":"1.9","Tissue RNA - gallbladder [nTPM]":"1.2","Tissue RNA - heart muscle [nTPM]":"44.9","Tissue RNA - hippocampal formation [nTPM]":"6.5","Tissue RNA - hypothalamus [nTPM]":"3.1","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"0.7","Tissue RNA - lymph node [nTPM]":"3.0","Tissue RNA - medulla oblongata [nTPM]":"3.7","Tissue RNA - midbrain [nTPM]":"3.9","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"1.0","Tissue RNA - placenta [nTPM]":"6.2","Tissue RNA - pons [nTPM]":"3.2","Tissue RNA - prostate [nTPM]":"16.2","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"49.7","Tissue RNA - salivary gland [nTPM]":"16.7","Tissue RNA - seminal vesicle [nTPM]":"5.0","Tissue RNA - skeletal muscle [nTPM]":"4442.6","Tissue RNA - skin 1 [nTPM]":"1.0","Tissue RNA - small intestine [nTPM]":"1.9","Tissue RNA - smooth muscle [nTPM]":"7.4","Tissue RNA - spinal cord [nTPM]":"3.1","Tissue RNA - spleen [nTPM]":"1.3","Tissue RNA - stomach 1 [nTPM]":"0.8","Tissue RNA - testis [nTPM]":"5.7","Tissue RNA - thalamus [nTPM]":"3.6","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"0.6","Tissue RNA - tongue [nTPM]":"1892.7","Tissue RNA - tonsil [nTPM]":"1.0","Tissue RNA - urinary bladder [nTPM]":"5.7","Tissue RNA - vagina [nTPM]":"0.9","Tissue RNA - white matter [nTPM]":"6.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"19.3","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.6","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"38.5","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.6","Cell RNA - HMC-1 [nTPM]":"4.7","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.7","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"67.4","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"3.5","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"0.8","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"5.1","Brain RNA - basal ganglia [nTPM]":"6.0","Brain RNA - cerebellum [nTPM]":"4.9","Brain RNA - cerebral cortex [nTPM]":"10.0","Brain RNA - hippocampal formation [nTPM]":"6.5","Brain RNA - hypothalamus [nTPM]":"3.1","Brain RNA - medulla oblongata [nTPM]":"3.7","Brain RNA - midbrain [nTPM]":"3.9","Brain RNA - pons [nTPM]":"3.2","Brain RNA - spinal cord [nTPM]":"3.1","Brain RNA - thalamus [nTPM]":"3.6","Brain RNA - white matter [nTPM]":"6.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"3.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.9","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"3.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"25.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.6","Single Cell Type RNA - Spermatocytes [nTPM]":"1.2","Single Cell Type RNA - Spermatogonia [nTPM]":"1.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.5","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"CATSPER1","Gene synonym":["CATSPER"],"Ensembl":"ENSG00000175294","Gene description":"Cation channel sperm associated 1","Uniprot":["Q8NEC5"],"Chromosome":"11","Position":"66016752-66026479","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Differentiation","Ion transport","Spermatogenesis","Transport"],"Molecular function":["Calcium channel","Developmental protein","Ion channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"34","RNA tissue specific nTPM":{"testis":"17.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"44.0","granulocytes":"99.6","Hofbauer cells":"19.9","monocytes":"27.3","NK-cells":"42.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"16.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"4.4","EFO-21":"4.0","HEL":"2.8","HMC-1":"5.1"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 60: Granulocytes - Receptor signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.79e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.02e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"17.3","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"1.0","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"4.4","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"4.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.8","Cell RNA - GAMG [nTPM]":"1.4","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.8","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"2.8","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"5.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.3","Cell RNA - hTERT-HME1 [nTPM]":"0.5","Cell RNA - hTERT-RPE1 [nTPM]":"0.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.7","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"1.5","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"1.4","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.6","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"1.1","Cell RNA - U-2 OS [nTPM]":"2.2","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.8","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"0.6","Blood RNA - basophil [nTPM]":"16.9","Blood RNA - classical monocyte [nTPM]":"5.8","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"2.4","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"3.7","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"2.3","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.4","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"9.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"44.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"99.6","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"17.0","Single Cell Type RNA - Langerhans cells [nTPM]":"12.2","Single Cell Type RNA - Late spermatids [nTPM]":"4.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"15.4","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"27.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"42.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"1.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.9","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"4.5","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"CATSPER2","Gene synonym":[],"Ensembl":"ENSG00000166762","Gene description":"Cation channel sperm associated 2","Uniprot":["Q96P56"],"Chromosome":"15","Position":"43628503-43668118","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Differentiation","Ion transport","Spermatogenesis","Transport"],"Molecular function":["Calcium channel","Developmental protein","Ion channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"14.6","retina":"22.8","testis":"15.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"254.4","Early spermatids":"73.6","Rod photoreceptor cells":"221.8","Spermatocytes":"117.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"14.6"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"11.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.11e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-5"},"Tissue RNA - adipose tissue [nTPM]":"1.2","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"2.0","Tissue RNA - appendix [nTPM]":"0.8","Tissue RNA - basal ganglia [nTPM]":"2.2","Tissue RNA - bone marrow [nTPM]":"4.2","Tissue RNA - breast [nTPM]":"1.8","Tissue RNA - cerebellum [nTPM]":"14.6","Tissue RNA - cerebral cortex [nTPM]":"4.0","Tissue RNA - cervix [nTPM]":"1.3","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"2.3","Tissue RNA - duodenum [nTPM]":"3.3","Tissue RNA - endometrium 1 [nTPM]":"1.4","Tissue RNA - epididymis [nTPM]":"5.4","Tissue RNA - esophagus [nTPM]":"2.4","Tissue RNA - fallopian tube [nTPM]":"1.4","Tissue RNA - gallbladder [nTPM]":"0.7","Tissue RNA - heart muscle [nTPM]":"0.9","Tissue RNA - hippocampal formation [nTPM]":"2.2","Tissue RNA - hypothalamus [nTPM]":"0.7","Tissue RNA - kidney [nTPM]":"1.4","Tissue RNA - liver [nTPM]":"1.5","Tissue RNA - lung [nTPM]":"1.2","Tissue RNA - lymph node [nTPM]":"2.0","Tissue RNA - medulla oblongata [nTPM]":"1.4","Tissue RNA - midbrain [nTPM]":"0.6","Tissue RNA - ovary [nTPM]":"1.6","Tissue RNA - pancreas [nTPM]":"1.2","Tissue RNA - parathyroid gland [nTPM]":"4.0","Tissue RNA - pituitary gland [nTPM]":"3.2","Tissue RNA - placenta [nTPM]":"0.8","Tissue RNA - pons [nTPM]":"1.7","Tissue RNA - prostate [nTPM]":"1.6","Tissue RNA - rectum [nTPM]":"2.3","Tissue RNA - retina [nTPM]":"22.8","Tissue RNA - salivary gland [nTPM]":"1.6","Tissue RNA - seminal vesicle [nTPM]":"2.2","Tissue RNA - skeletal muscle [nTPM]":"1.2","Tissue RNA - skin 1 [nTPM]":"5.4","Tissue RNA - small intestine [nTPM]":"3.8","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"1.5","Tissue RNA - stomach 1 [nTPM]":"1.8","Tissue RNA - testis [nTPM]":"15.5","Tissue RNA - thalamus [nTPM]":"0.9","Tissue RNA - thymus [nTPM]":"0.9","Tissue RNA - thyroid gland [nTPM]":"1.9","Tissue RNA - tongue [nTPM]":"1.5","Tissue RNA - tonsil [nTPM]":"1.5","Tissue RNA - urinary bladder [nTPM]":"1.7","Tissue RNA - vagina [nTPM]":"1.3","Tissue RNA - white matter [nTPM]":"3.1","Cell RNA - A-431 [nTPM]":"2.0","Cell RNA - A549 [nTPM]":"2.8","Cell RNA - AF22 [nTPM]":"1.2","Cell RNA - AN3-CA [nTPM]":"4.4","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"2.0","Cell RNA - BJ [nTPM]":"0.7","Cell RNA - BJ hTERT+ [nTPM]":"1.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.9","Cell RNA - CACO-2 [nTPM]":"0.7","Cell RNA - CAPAN-2 [nTPM]":"1.1","Cell RNA - Daudi [nTPM]":"2.4","Cell RNA - EFO-21 [nTPM]":"1.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.5","Cell RNA - GAMG [nTPM]":"1.4","Cell RNA - HaCaT [nTPM]":"4.4","Cell RNA - HAP1 [nTPM]":"1.1","Cell RNA - HBEC3-KT [nTPM]":"3.9","Cell RNA - HBF TERT88 [nTPM]":"1.2","Cell RNA - HDLM-2 [nTPM]":"2.0","Cell RNA - HEK 293 [nTPM]":"5.4","Cell RNA - HEL [nTPM]":"7.0","Cell RNA - HeLa [nTPM]":"11.2","Cell RNA - Hep G2 [nTPM]":"1.0","Cell RNA - HHSteC [nTPM]":"1.8","Cell RNA - HL-60 [nTPM]":"1.6","Cell RNA - HMC-1 [nTPM]":"2.2","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"3.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.7","Cell RNA - hTERT-HME1 [nTPM]":"4.3","Cell RNA - hTERT-RPE1 [nTPM]":"3.2","Cell RNA - HUVEC TERT2 [nTPM]":"1.5","Cell RNA - JURKAT [nTPM]":"4.3","Cell RNA - K-562 [nTPM]":"2.8","Cell RNA - Karpas-707 [nTPM]":"2.4","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"0.5","Cell RNA - MOLT-4 [nTPM]":"1.3","Cell RNA - NB-4 [nTPM]":"2.8","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"2.7","Cell RNA - PC-3 [nTPM]":"1.2","Cell RNA - REH [nTPM]":"1.9","Cell RNA - RH-30 [nTPM]":"1.4","Cell RNA - RPMI-8226 [nTPM]":"1.1","Cell RNA - RPTEC TERT1 [nTPM]":"2.4","Cell RNA - RT4 [nTPM]":"3.2","Cell RNA - SCLC-21H [nTPM]":"2.6","Cell RNA - SH-SY5Y [nTPM]":"0.9","Cell RNA - SiHa [nTPM]":"1.1","Cell RNA - SK-BR-3 [nTPM]":"1.6","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"1.6","Cell RNA - T-47d [nTPM]":"3.2","Cell RNA - THP-1 [nTPM]":"1.5","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"3.0","Cell RNA - U-2 OS [nTPM]":"1.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"1.8","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"5.1","Cell RNA - U-87 MG [nTPM]":"2.1","Cell RNA - U-937 [nTPM]":"4.9","Cell RNA - WM-115 [nTPM]":"1.1","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"1.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.0","Brain RNA - basal ganglia [nTPM]":"2.2","Brain RNA - cerebellum [nTPM]":"14.6","Brain RNA - cerebral cortex [nTPM]":"4.0","Brain RNA - hippocampal formation [nTPM]":"2.2","Brain RNA - hypothalamus [nTPM]":"0.7","Brain RNA - medulla oblongata [nTPM]":"1.4","Brain RNA - midbrain [nTPM]":"0.6","Brain RNA - pons [nTPM]":"1.7","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.9","Brain RNA - white matter [nTPM]":"3.1","Single Cell Type RNA - Adipocytes [nTPM]":"4.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"4.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"56.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"8.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"254.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.0","Single Cell Type RNA - dendritic cells [nTPM]":"6.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.2","Single Cell Type RNA - Early spermatids [nTPM]":"73.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.5","Single Cell Type RNA - Endothelial cells [nTPM]":"6.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.5","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.1","Single Cell Type RNA - Fibroblasts [nTPM]":"3.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.2","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"29.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.6","Single Cell Type RNA - Hepatocytes [nTPM]":"3.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.3","Single Cell Type RNA - Horizontal cells [nTPM]":"38.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.6","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"5.0","Single Cell Type RNA - Langerhans cells [nTPM]":"6.5","Single Cell Type RNA - Late spermatids [nTPM]":"37.4","Single Cell Type RNA - Leydig cells [nTPM]":"6.2","Single Cell Type RNA - Macrophages [nTPM]":"4.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"4.5","Single Cell Type RNA - Muller glia cells [nTPM]":"13.4","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.0","Single Cell Type RNA - Paneth cells [nTPM]":"3.3","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"1.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"221.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.1","Single Cell Type RNA - Spermatocytes [nTPM]":"117.4","Single Cell Type RNA - Spermatogonia [nTPM]":"17.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.0","Single Cell Type RNA - T-cells [nTPM]":"4.6","Single Cell Type RNA - Theca cells [nTPM]":"5.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.5","Single Cell Type RNA - Urothelial cells [nTPM]":"8.4"},{"Gene":"CAV1","Gene synonym":["CAV"],"Ensembl":"ENSG00000105974","Gene description":"Caveolin 1","Uniprot":["Q03135"],"Chromosome":"7","Position":"116524994-116561179","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Congenital generalized lipodystrophy","Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"2160.5","Alveolar cells type 1":"3557.7","Basal keratinocytes":"1375.3","Endothelial cells":"1024.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"basophil":"14.6","memory B-cell":"5.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"57","RNA blood lineage specific nTPM":{"B-cells":"5.1","granulocytes":"14.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC TERT1":"2140.5","BJ hTERT+":"2371.6","HBEC3-KT":"2333.7","LHCN-M2":"2372.1","U-138 MG":"1894.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"122.1"},"Antibody":["CAB003791","HPA049326"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB003791":"AB_562068","HPA049326":"AB_2680714"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.17e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.29e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-3"},"Tissue RNA - adipose tissue [nTPM]":"621.1","Tissue RNA - adrenal gland [nTPM]":"17.4","Tissue RNA - amygdala [nTPM]":"12.7","Tissue RNA - appendix [nTPM]":"44.7","Tissue RNA - basal ganglia [nTPM]":"15.3","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"284.5","Tissue RNA - cerebellum [nTPM]":"14.3","Tissue RNA - cerebral cortex [nTPM]":"21.6","Tissue RNA - cervix [nTPM]":"267.0","Tissue RNA - choroid plexus [nTPM]":"11.8","Tissue RNA - colon [nTPM]":"298.8","Tissue RNA - duodenum [nTPM]":"32.3","Tissue RNA - endometrium 1 [nTPM]":"190.9","Tissue RNA - epididymis [nTPM]":"72.5","Tissue RNA - esophagus [nTPM]":"135.1","Tissue RNA - fallopian tube [nTPM]":"152.5","Tissue RNA - gallbladder [nTPM]":"148.2","Tissue RNA - heart muscle [nTPM]":"276.5","Tissue RNA - hippocampal formation [nTPM]":"12.2","Tissue RNA - hypothalamus [nTPM]":"13.9","Tissue RNA - kidney [nTPM]":"18.4","Tissue RNA - liver [nTPM]":"26.6","Tissue RNA - lung [nTPM]":"592.0","Tissue RNA - lymph node [nTPM]":"30.3","Tissue RNA - medulla oblongata [nTPM]":"15.1","Tissue RNA - midbrain [nTPM]":"13.4","Tissue RNA - ovary [nTPM]":"137.4","Tissue RNA - pancreas [nTPM]":"24.6","Tissue RNA - parathyroid gland [nTPM]":"21.4","Tissue RNA - pituitary gland [nTPM]":"6.8","Tissue RNA - placenta [nTPM]":"449.2","Tissue RNA - pons [nTPM]":"14.6","Tissue RNA - prostate [nTPM]":"110.3","Tissue RNA - rectum [nTPM]":"93.6","Tissue RNA - retina [nTPM]":"31.4","Tissue RNA - salivary gland [nTPM]":"58.0","Tissue RNA - seminal vesicle [nTPM]":"175.5","Tissue RNA - skeletal muscle [nTPM]":"102.9","Tissue RNA - skin 1 [nTPM]":"104.9","Tissue RNA - small intestine [nTPM]":"89.4","Tissue RNA - smooth muscle [nTPM]":"274.2","Tissue RNA - spinal cord [nTPM]":"14.3","Tissue RNA - spleen [nTPM]":"199.1","Tissue RNA - stomach 1 [nTPM]":"120.8","Tissue RNA - testis [nTPM]":"25.8","Tissue RNA - thalamus [nTPM]":"16.1","Tissue RNA - thymus [nTPM]":"25.2","Tissue RNA - thyroid gland [nTPM]":"168.4","Tissue RNA - tongue [nTPM]":"184.6","Tissue RNA - tonsil [nTPM]":"20.3","Tissue RNA - urinary bladder [nTPM]":"202.0","Tissue RNA - vagina [nTPM]":"124.1","Tissue RNA - white matter [nTPM]":"16.2","Cell RNA - A-431 [nTPM]":"458.7","Cell RNA - A549 [nTPM]":"344.3","Cell RNA - AF22 [nTPM]":"9.5","Cell RNA - AN3-CA [nTPM]":"3.7","Cell RNA - ASC diff [nTPM]":"1406.6","Cell RNA - ASC TERT1 [nTPM]":"2140.5","Cell RNA - BEWO [nTPM]":"20.6","Cell RNA - BJ [nTPM]":"1055.8","Cell RNA - BJ hTERT+ [nTPM]":"2371.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"566.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"591.2","Cell RNA - CACO-2 [nTPM]":"3.0","Cell RNA - CAPAN-2 [nTPM]":"652.4","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"365.8","Cell RNA - fHDF\/TERT166 [nTPM]":"1228.5","Cell RNA - GAMG [nTPM]":"494.8","Cell RNA - HaCaT [nTPM]":"828.2","Cell RNA - HAP1 [nTPM]":"2.2","Cell RNA - HBEC3-KT [nTPM]":"2333.7","Cell RNA - HBF TERT88 [nTPM]":"840.3","Cell RNA - HDLM-2 [nTPM]":"36.0","Cell RNA - HEK 293 [nTPM]":"19.5","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"128.7","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"196.9","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"2.1","Cell RNA - HSkMC [nTPM]":"736.9","Cell RNA - hTCEpi [nTPM]":"481.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"805.7","Cell RNA - hTERT-HME1 [nTPM]":"536.0","Cell RNA - hTERT-RPE1 [nTPM]":"539.0","Cell RNA - HUVEC TERT2 [nTPM]":"1749.9","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"23.4","Cell RNA - LHCN-M2 [nTPM]":"2372.1","Cell RNA - MCF7 [nTPM]":"45.2","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"33.7","Cell RNA - OE19 [nTPM]":"1.2","Cell RNA - PC-3 [nTPM]":"173.9","Cell RNA - REH [nTPM]":"5.2","Cell RNA - RH-30 [nTPM]":"25.2","Cell RNA - RPMI-8226 [nTPM]":"251.0","Cell RNA - RPTEC TERT1 [nTPM]":"317.0","Cell RNA - RT4 [nTPM]":"2.0","Cell RNA - SCLC-21H [nTPM]":"1.0","Cell RNA - SH-SY5Y [nTPM]":"0.6","Cell RNA - SiHa [nTPM]":"328.3","Cell RNA - SK-BR-3 [nTPM]":"20.1","Cell RNA - SK-MEL-30 [nTPM]":"52.3","Cell RNA - SuSa [nTPM]":"137.8","Cell RNA - T-47d [nTPM]":"1.6","Cell RNA - THP-1 [nTPM]":"3.9","Cell RNA - TIME [nTPM]":"1349.3","Cell RNA - U-138 MG [nTPM]":"1894.8","Cell RNA - U-2 OS [nTPM]":"212.4","Cell RNA - U-2197 [nTPM]":"730.6","Cell RNA - U-251 MG [nTPM]":"298.9","Cell RNA - U-266\/70 [nTPM]":"96.8","Cell RNA - U-266\/84 [nTPM]":"15.8","Cell RNA - U-698 [nTPM]":"1.9","Cell RNA - U-87 MG [nTPM]":"758.4","Cell RNA - U-937 [nTPM]":"0.9","Cell RNA - WM-115 [nTPM]":"701.0","Blood RNA - basophil [nTPM]":"14.6","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"5.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.9","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"12.7","Brain RNA - basal ganglia [nTPM]":"15.3","Brain RNA - cerebellum [nTPM]":"14.3","Brain RNA - cerebral cortex [nTPM]":"21.6","Brain RNA - hippocampal formation [nTPM]":"12.2","Brain RNA - hypothalamus [nTPM]":"13.9","Brain RNA - medulla oblongata [nTPM]":"15.1","Brain RNA - midbrain [nTPM]":"13.4","Brain RNA - pons [nTPM]":"14.6","Brain RNA - spinal cord [nTPM]":"14.3","Brain RNA - thalamus [nTPM]":"16.1","Brain RNA - white matter [nTPM]":"16.2","Single Cell Type RNA - Adipocytes [nTPM]":"2160.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3557.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"123.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"15.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1375.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"392.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"534.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"316.4","Single Cell Type RNA - Bipolar cells [nTPM]":"8.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"190.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"286.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"107.2","Single Cell Type RNA - Club cells [nTPM]":"342.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"64.3","Single Cell Type RNA - dendritic cells [nTPM]":"7.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"76.8","Single Cell Type RNA - Early spermatids [nTPM]":"2.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"102.3","Single Cell Type RNA - Endothelial cells [nTPM]":"1024.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"16.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"449.5","Single Cell Type RNA - Fibroblasts [nTPM]":"326.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.3","Single Cell Type RNA - granulocytes [nTPM]":"13.9","Single Cell Type RNA - Granulosa cells [nTPM]":"6.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"450.5","Single Cell Type RNA - Hepatocytes [nTPM]":"5.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.0","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"11.0","Single Cell Type RNA - Langerhans cells [nTPM]":"187.1","Single Cell Type RNA - Late spermatids [nTPM]":"13.4","Single Cell Type RNA - Leydig cells [nTPM]":"377.2","Single Cell Type RNA - Macrophages [nTPM]":"10.7","Single Cell Type RNA - Melanocytes [nTPM]":"439.4","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"3.7","Single Cell Type RNA - Muller glia cells [nTPM]":"249.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"43.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"565.4","Single Cell Type RNA - Plasma cells [nTPM]":"56.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"512.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"30.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.7","Single Cell Type RNA - Sertoli cells [nTPM]":"558.8","Single Cell Type RNA - Skeletal myocytes [nTPM]":"152.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"751.4","Single Cell Type RNA - Spermatocytes [nTPM]":"2.1","Single Cell Type RNA - Spermatogonia [nTPM]":"5.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"39.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"610.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"117.0","Single Cell Type RNA - T-cells [nTPM]":"16.7","Single Cell Type RNA - Theca cells [nTPM]":"59.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.4","Single Cell Type RNA - Urothelial cells [nTPM]":"93.3"},{"Gene":"CAV3","Gene synonym":["LGMD1C","LQT9","VIP-21","VIP21"],"Ensembl":"ENSG00000182533","Gene description":"Caveolin 3","Uniprot":["P56539"],"Chromosome":"3","Position":"8733802-8841808","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cardiomyopathy","Disease variant","Limb-girdle muscular dystrophy","Long QT syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"skeletal muscle":"182.7","tongue":"72.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"22.9","Early spermatids":"4.2","Sertoli cells":"6.6","Skeletal myocytes":"11.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"0.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"RH-30":"94.9"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017518","CAB018557","HPA054488"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB017518":"AB_628860","CAB018557":"AB_626814","HPA054488":"AB_2682504"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.79e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"5.7","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"27.4","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.9","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"1.9","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"2.5","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"182.7","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"72.8","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"4.9","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"23.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"94.9","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"22.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"4.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"2.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CBL","Gene synonym":["c-Cbl","CBL2","RNF55"],"Ensembl":"ENSG00000110395","Gene description":"Cbl proto-oncogene","Uniprot":["P22681"],"Chromosome":"11","Position":"119206298-119313926","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"8.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004350","HPA027956"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"67000","Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB004350":"AB_2244054","HPA027956":"AB_10601094"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.8","Tissue RNA - adrenal gland [nTPM]":"4.0","Tissue RNA - amygdala [nTPM]":"5.6","Tissue RNA - appendix [nTPM]":"9.5","Tissue RNA - basal ganglia [nTPM]":"5.7","Tissue RNA - bone marrow [nTPM]":"8.5","Tissue RNA - breast [nTPM]":"5.6","Tissue RNA - cerebellum [nTPM]":"5.3","Tissue RNA - cerebral cortex [nTPM]":"6.5","Tissue RNA - cervix [nTPM]":"5.0","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"6.2","Tissue RNA - duodenum [nTPM]":"3.9","Tissue RNA - endometrium 1 [nTPM]":"6.5","Tissue RNA - epididymis [nTPM]":"3.4","Tissue RNA - esophagus [nTPM]":"5.6","Tissue RNA - fallopian tube [nTPM]":"5.6","Tissue RNA - gallbladder [nTPM]":"3.9","Tissue RNA - heart muscle [nTPM]":"4.1","Tissue RNA - hippocampal formation [nTPM]":"5.3","Tissue RNA - hypothalamus [nTPM]":"8.1","Tissue RNA - kidney [nTPM]":"4.4","Tissue RNA - liver [nTPM]":"2.7","Tissue RNA - lung [nTPM]":"7.9","Tissue RNA - lymph node [nTPM]":"10.7","Tissue RNA - medulla oblongata [nTPM]":"5.8","Tissue RNA - midbrain [nTPM]":"6.3","Tissue RNA - ovary [nTPM]":"3.7","Tissue RNA - pancreas [nTPM]":"3.8","Tissue RNA - parathyroid gland [nTPM]":"6.1","Tissue RNA - pituitary gland [nTPM]":"2.9","Tissue RNA - placenta [nTPM]":"6.4","Tissue RNA - pons [nTPM]":"6.5","Tissue RNA - prostate [nTPM]":"4.0","Tissue RNA - rectum [nTPM]":"5.0","Tissue RNA - retina [nTPM]":"8.3","Tissue RNA - salivary gland [nTPM]":"3.6","Tissue RNA - seminal vesicle [nTPM]":"4.6","Tissue RNA - skeletal muscle [nTPM]":"2.5","Tissue RNA - skin 1 [nTPM]":"5.2","Tissue RNA - small intestine [nTPM]":"6.6","Tissue RNA - smooth muscle [nTPM]":"7.4","Tissue RNA - spinal cord [nTPM]":"5.2","Tissue RNA - spleen [nTPM]":"9.9","Tissue RNA - stomach 1 [nTPM]":"5.2","Tissue RNA - testis [nTPM]":"18.2","Tissue RNA - thalamus [nTPM]":"7.9","Tissue RNA - thymus [nTPM]":"22.5","Tissue RNA - thyroid gland [nTPM]":"4.1","Tissue RNA - tongue [nTPM]":"3.2","Tissue RNA - tonsil [nTPM]":"11.2","Tissue RNA - urinary bladder [nTPM]":"5.8","Tissue RNA - vagina [nTPM]":"4.9","Tissue RNA - white matter [nTPM]":"6.0","Cell RNA - A-431 [nTPM]":"10.7","Cell RNA - A549 [nTPM]":"7.6","Cell RNA - AF22 [nTPM]":"26.6","Cell RNA - AN3-CA [nTPM]":"16.7","Cell RNA - ASC diff [nTPM]":"7.8","Cell RNA - ASC TERT1 [nTPM]":"9.2","Cell RNA - BEWO [nTPM]":"16.0","Cell RNA - BJ [nTPM]":"11.2","Cell RNA - BJ hTERT+ [nTPM]":"11.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.2","Cell RNA - CACO-2 [nTPM]":"16.7","Cell RNA - CAPAN-2 [nTPM]":"12.6","Cell RNA - Daudi [nTPM]":"25.1","Cell RNA - EFO-21 [nTPM]":"10.0","Cell RNA - fHDF\/TERT166 [nTPM]":"14.0","Cell RNA - GAMG [nTPM]":"21.7","Cell RNA - HaCaT [nTPM]":"15.2","Cell RNA - HAP1 [nTPM]":"18.4","Cell RNA - HBEC3-KT [nTPM]":"9.4","Cell RNA - HBF TERT88 [nTPM]":"22.7","Cell RNA - HDLM-2 [nTPM]":"14.8","Cell RNA - HEK 293 [nTPM]":"4.7","Cell RNA - HEL [nTPM]":"26.4","Cell RNA - HeLa [nTPM]":"6.2","Cell RNA - Hep G2 [nTPM]":"5.1","Cell RNA - HHSteC [nTPM]":"9.5","Cell RNA - HL-60 [nTPM]":"30.3","Cell RNA - HMC-1 [nTPM]":"27.9","Cell RNA - HSkMC [nTPM]":"8.1","Cell RNA - hTCEpi [nTPM]":"10.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.7","Cell RNA - hTERT-HME1 [nTPM]":"28.4","Cell RNA - hTERT-RPE1 [nTPM]":"11.1","Cell RNA - HUVEC TERT2 [nTPM]":"26.3","Cell RNA - JURKAT [nTPM]":"23.7","Cell RNA - K-562 [nTPM]":"21.7","Cell RNA - Karpas-707 [nTPM]":"9.9","Cell RNA - LHCN-M2 [nTPM]":"19.1","Cell RNA - MCF7 [nTPM]":"11.3","Cell RNA - MOLT-4 [nTPM]":"16.2","Cell RNA - NB-4 [nTPM]":"17.0","Cell RNA - NTERA-2 [nTPM]":"14.0","Cell RNA - OE19 [nTPM]":"9.2","Cell RNA - PC-3 [nTPM]":"8.8","Cell RNA - REH [nTPM]":"17.5","Cell RNA - RH-30 [nTPM]":"13.5","Cell RNA - RPMI-8226 [nTPM]":"4.6","Cell RNA - RPTEC TERT1 [nTPM]":"9.3","Cell RNA - RT4 [nTPM]":"8.2","Cell RNA - SCLC-21H [nTPM]":"3.7","Cell RNA - SH-SY5Y [nTPM]":"11.3","Cell RNA - SiHa [nTPM]":"20.9","Cell RNA - SK-BR-3 [nTPM]":"8.8","Cell RNA - SK-MEL-30 [nTPM]":"7.3","Cell RNA - SuSa [nTPM]":"18.1","Cell RNA - T-47d [nTPM]":"9.4","Cell RNA - THP-1 [nTPM]":"24.8","Cell RNA - TIME [nTPM]":"22.8","Cell RNA - U-138 MG [nTPM]":"16.0","Cell RNA - U-2 OS [nTPM]":"11.5","Cell RNA - U-2197 [nTPM]":"11.6","Cell RNA - U-251 MG [nTPM]":"14.7","Cell RNA - U-266\/70 [nTPM]":"3.3","Cell RNA - U-266\/84 [nTPM]":"5.3","Cell RNA - U-698 [nTPM]":"19.9","Cell RNA - U-87 MG [nTPM]":"6.7","Cell RNA - U-937 [nTPM]":"25.4","Cell RNA - WM-115 [nTPM]":"11.9","Blood RNA - basophil [nTPM]":"0.8","Blood RNA - classical monocyte [nTPM]":"2.4","Blood RNA - eosinophil [nTPM]":"2.0","Blood RNA - gdT-cell [nTPM]":"0.9","Blood RNA - intermediate monocyte [nTPM]":"2.8","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"2.6","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"1.3","Blood RNA - neutrophil [nTPM]":"8.6","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"2.5","Blood RNA - plasmacytoid DC [nTPM]":"1.4","Blood RNA - T-reg [nTPM]":"1.0","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"5.6","Brain RNA - basal ganglia [nTPM]":"5.7","Brain RNA - cerebellum [nTPM]":"5.3","Brain RNA - cerebral cortex [nTPM]":"6.5","Brain RNA - hippocampal formation [nTPM]":"5.3","Brain RNA - hypothalamus [nTPM]":"8.1","Brain RNA - medulla oblongata [nTPM]":"5.8","Brain RNA - midbrain [nTPM]":"6.3","Brain RNA - pons [nTPM]":"6.5","Brain RNA - spinal cord [nTPM]":"5.2","Brain RNA - thalamus [nTPM]":"7.9","Brain RNA - white matter [nTPM]":"6.0","Single Cell Type RNA - Adipocytes [nTPM]":"23.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.3","Single Cell Type RNA - Astrocytes [nTPM]":"23.5","Single Cell Type RNA - B-cells [nTPM]":"23.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.4","Single Cell Type RNA - Bipolar cells [nTPM]":"14.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"6.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.3","Single Cell Type RNA - dendritic cells [nTPM]":"24.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.1","Single Cell Type RNA - Early spermatids [nTPM]":"28.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.6","Single Cell Type RNA - Endothelial cells [nTPM]":"23.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"5.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"38.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.5","Single Cell Type RNA - Fibroblasts [nTPM]":"9.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.8","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"20.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.0","Single Cell Type RNA - Hepatocytes [nTPM]":"3.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.0","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"39.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.9","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"59.1","Single Cell Type RNA - Langerhans cells [nTPM]":"43.2","Single Cell Type RNA - Late spermatids [nTPM]":"42.0","Single Cell Type RNA - Leydig cells [nTPM]":"7.8","Single Cell Type RNA - Macrophages [nTPM]":"41.2","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"45.0","Single Cell Type RNA - monocytes [nTPM]":"46.8","Single Cell Type RNA - Muller glia cells [nTPM]":"13.2","Single Cell Type RNA - NK-cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"26.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.6","Single Cell Type RNA - Paneth cells [nTPM]":"11.6","Single Cell Type RNA - Peritubular cells [nTPM]":"12.8","Single Cell Type RNA - Plasma cells [nTPM]":"19.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.7","Single Cell Type RNA - Spermatocytes [nTPM]":"38.0","Single Cell Type RNA - Spermatogonia [nTPM]":"36.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.0","Single Cell Type RNA - T-cells [nTPM]":"24.9","Single Cell Type RNA - Theca cells [nTPM]":"10.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.1","Single Cell Type RNA - Urothelial cells [nTPM]":"10.9"},{"Gene":"CBS","Gene synonym":["HIP4"],"Ensembl":"ENSG00000160200","Gene description":"Cystathionine beta-synthase","Uniprot":["P35520"],"Chromosome":"21","Position":"43053191-43076943","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Amino-acid biosynthesis","Cysteine biosynthesis"],"Molecular function":["Allosteric enzyme","Lyase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"174.9","pancreas":"99.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"2.3","Cardiomyocytes":"4.9","Hepatocytes":"3.6","Ionocytes":"2.0","Melanocytes":"5.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"51","RNA blood cell specific nTPM":{"neutrophil":"5.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"51","RNA blood lineage specific nTPM":{"granulocytes":"5.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"177.5","HAP1":"172.8","HHSteC":"224.1","MCF7":"197.7","RPMI-8226":"197.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001223"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA001223":"AB_1846112"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.68e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.76e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.73e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.6","Tissue RNA - adrenal gland [nTPM]":"2.8","Tissue RNA - amygdala [nTPM]":"42.5","Tissue RNA - appendix [nTPM]":"1.0","Tissue RNA - basal ganglia [nTPM]":"39.5","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"3.4","Tissue RNA - cerebellum [nTPM]":"58.5","Tissue RNA - cerebral cortex [nTPM]":"55.3","Tissue RNA - cervix [nTPM]":"12.3","Tissue RNA - choroid plexus [nTPM]":"29.3","Tissue RNA - colon [nTPM]":"4.8","Tissue RNA - duodenum [nTPM]":"3.0","Tissue RNA - endometrium 1 [nTPM]":"4.5","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"2.0","Tissue RNA - fallopian tube [nTPM]":"5.8","Tissue RNA - gallbladder [nTPM]":"1.2","Tissue RNA - heart muscle [nTPM]":"7.7","Tissue RNA - hippocampal formation [nTPM]":"41.4","Tissue RNA - hypothalamus [nTPM]":"40.3","Tissue RNA - kidney [nTPM]":"3.8","Tissue RNA - liver [nTPM]":"174.9","Tissue RNA - lung [nTPM]":"10.2","Tissue RNA - lymph node [nTPM]":"2.7","Tissue RNA - medulla oblongata [nTPM]":"42.5","Tissue RNA - midbrain [nTPM]":"44.6","Tissue RNA - ovary [nTPM]":"30.3","Tissue RNA - pancreas [nTPM]":"99.0","Tissue RNA - parathyroid gland [nTPM]":"2.5","Tissue RNA - pituitary gland [nTPM]":"8.8","Tissue RNA - placenta [nTPM]":"1.2","Tissue RNA - pons [nTPM]":"42.7","Tissue RNA - prostate [nTPM]":"12.7","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"2.5","Tissue RNA - salivary gland [nTPM]":"19.9","Tissue RNA - seminal vesicle [nTPM]":"1.1","Tissue RNA - skeletal muscle [nTPM]":"1.1","Tissue RNA - skin 1 [nTPM]":"2.3","Tissue RNA - small intestine [nTPM]":"7.0","Tissue RNA - smooth muscle [nTPM]":"2.3","Tissue RNA - spinal cord [nTPM]":"38.4","Tissue RNA - spleen [nTPM]":"1.7","Tissue RNA - stomach 1 [nTPM]":"16.5","Tissue RNA - testis [nTPM]":"2.0","Tissue RNA - thalamus [nTPM]":"48.1","Tissue RNA - thymus [nTPM]":"0.7","Tissue RNA - thyroid gland [nTPM]":"17.4","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"1.4","Tissue RNA - urinary bladder [nTPM]":"11.6","Tissue RNA - vagina [nTPM]":"6.2","Tissue RNA - white matter [nTPM]":"45.4","Cell RNA - A-431 [nTPM]":"30.0","Cell RNA - A549 [nTPM]":"17.0","Cell RNA - AF22 [nTPM]":"31.3","Cell RNA - AN3-CA [nTPM]":"113.4","Cell RNA - ASC diff [nTPM]":"48.9","Cell RNA - ASC TERT1 [nTPM]":"31.5","Cell RNA - BEWO [nTPM]":"177.5","Cell RNA - BJ [nTPM]":"39.5","Cell RNA - BJ hTERT+ [nTPM]":"10.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.4","Cell RNA - CACO-2 [nTPM]":"53.7","Cell RNA - CAPAN-2 [nTPM]":"1.5","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"19.2","Cell RNA - fHDF\/TERT166 [nTPM]":"67.2","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"1.5","Cell RNA - HAP1 [nTPM]":"172.8","Cell RNA - HBEC3-KT [nTPM]":"13.2","Cell RNA - HBF TERT88 [nTPM]":"3.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"20.5","Cell RNA - HEL [nTPM]":"12.3","Cell RNA - HeLa [nTPM]":"73.1","Cell RNA - Hep G2 [nTPM]":"63.8","Cell RNA - HHSteC [nTPM]":"224.1","Cell RNA - HL-60 [nTPM]":"7.9","Cell RNA - HMC-1 [nTPM]":"19.1","Cell RNA - HSkMC [nTPM]":"21.7","Cell RNA - hTCEpi [nTPM]":"1.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.0","Cell RNA - hTERT-HME1 [nTPM]":"16.4","Cell RNA - hTERT-RPE1 [nTPM]":"13.2","Cell RNA - HUVEC TERT2 [nTPM]":"38.6","Cell RNA - JURKAT [nTPM]":"85.6","Cell RNA - K-562 [nTPM]":"138.7","Cell RNA - Karpas-707 [nTPM]":"118.1","Cell RNA - LHCN-M2 [nTPM]":"11.1","Cell RNA - MCF7 [nTPM]":"197.7","Cell RNA - MOLT-4 [nTPM]":"16.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"20.3","Cell RNA - OE19 [nTPM]":"65.7","Cell RNA - PC-3 [nTPM]":"29.4","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"197.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.5","Cell RNA - RT4 [nTPM]":"15.5","Cell RNA - SCLC-21H [nTPM]":"57.8","Cell RNA - SH-SY5Y [nTPM]":"85.1","Cell RNA - SiHa [nTPM]":"78.5","Cell RNA - SK-BR-3 [nTPM]":"5.4","Cell RNA - SK-MEL-30 [nTPM]":"44.4","Cell RNA - SuSa [nTPM]":"18.4","Cell RNA - T-47d [nTPM]":"27.0","Cell RNA - THP-1 [nTPM]":"91.2","Cell RNA - TIME [nTPM]":"5.4","Cell RNA - U-138 MG [nTPM]":"0.8","Cell RNA - U-2 OS [nTPM]":"42.5","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"4.8","Cell RNA - U-266\/70 [nTPM]":"34.8","Cell RNA - U-266\/84 [nTPM]":"30.2","Cell RNA - U-698 [nTPM]":"41.2","Cell RNA - U-87 MG [nTPM]":"19.0","Cell RNA - U-937 [nTPM]":"11.0","Cell RNA - WM-115 [nTPM]":"53.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"5.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"42.5","Brain RNA - basal ganglia [nTPM]":"39.5","Brain RNA - cerebellum [nTPM]":"58.5","Brain RNA - cerebral cortex [nTPM]":"55.3","Brain RNA - hippocampal formation [nTPM]":"41.4","Brain RNA - hypothalamus [nTPM]":"40.3","Brain RNA - medulla oblongata [nTPM]":"42.5","Brain RNA - midbrain [nTPM]":"44.6","Brain RNA - pons [nTPM]":"42.7","Brain RNA - spinal cord [nTPM]":"38.4","Brain RNA - thalamus [nTPM]":"48.1","Brain RNA - white matter [nTPM]":"45.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.8","Single Cell Type RNA - Fibroblasts [nTPM]":"1.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"3.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"1.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"CCDC22","Gene synonym":["CXorf37","JM1"],"Ensembl":"ENSG00000101997","Gene description":"Coiled-coil domain containing 22","Uniprot":["O60826"],"Chromosome":"X","Position":"49235470-49250520","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Protein transport","Transport","Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000229","HPA000888","HPA075980"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Endoplasmic reticulum","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA000229":null,"HPA000888":"AB_1078420","HPA075980":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.17e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-3"},"Tissue RNA - adipose tissue [nTPM]":"10.3","Tissue RNA - adrenal gland [nTPM]":"12.3","Tissue RNA - amygdala [nTPM]":"9.4","Tissue RNA - appendix [nTPM]":"10.1","Tissue RNA - basal ganglia [nTPM]":"10.0","Tissue RNA - bone marrow [nTPM]":"18.6","Tissue RNA - breast [nTPM]":"10.3","Tissue RNA - cerebellum [nTPM]":"9.9","Tissue RNA - cerebral cortex [nTPM]":"10.8","Tissue RNA - cervix [nTPM]":"11.7","Tissue RNA - choroid plexus [nTPM]":"8.8","Tissue RNA - colon [nTPM]":"12.1","Tissue RNA - duodenum [nTPM]":"10.4","Tissue RNA - endometrium 1 [nTPM]":"12.2","Tissue RNA - epididymis [nTPM]":"5.3","Tissue RNA - esophagus [nTPM]":"14.2","Tissue RNA - fallopian tube [nTPM]":"11.3","Tissue RNA - gallbladder [nTPM]":"6.4","Tissue RNA - heart muscle [nTPM]":"12.8","Tissue RNA - hippocampal formation [nTPM]":"9.4","Tissue RNA - hypothalamus [nTPM]":"9.2","Tissue RNA - kidney [nTPM]":"12.3","Tissue RNA - liver [nTPM]":"12.9","Tissue RNA - lung [nTPM]":"10.7","Tissue RNA - lymph node [nTPM]":"15.0","Tissue RNA - medulla oblongata [nTPM]":"10.8","Tissue RNA - midbrain [nTPM]":"9.4","Tissue RNA - ovary [nTPM]":"11.2","Tissue RNA - pancreas [nTPM]":"14.2","Tissue RNA - parathyroid gland [nTPM]":"8.7","Tissue RNA - pituitary gland [nTPM]":"11.2","Tissue RNA - placenta [nTPM]":"6.9","Tissue RNA - pons [nTPM]":"10.1","Tissue RNA - prostate [nTPM]":"13.5","Tissue RNA - rectum [nTPM]":"5.2","Tissue RNA - retina [nTPM]":"4.7","Tissue RNA - salivary gland [nTPM]":"12.3","Tissue RNA - seminal vesicle [nTPM]":"8.7","Tissue RNA - skeletal muscle [nTPM]":"17.2","Tissue RNA - skin 1 [nTPM]":"13.8","Tissue RNA - small intestine [nTPM]":"13.4","Tissue RNA - smooth muscle [nTPM]":"6.0","Tissue RNA - spinal cord [nTPM]":"9.6","Tissue RNA - spleen [nTPM]":"20.5","Tissue RNA - stomach 1 [nTPM]":"12.9","Tissue RNA - testis [nTPM]":"3.8","Tissue RNA - thalamus [nTPM]":"10.0","Tissue RNA - thymus [nTPM]":"13.6","Tissue RNA - thyroid gland [nTPM]":"11.0","Tissue RNA - tongue [nTPM]":"7.7","Tissue RNA - tonsil [nTPM]":"8.5","Tissue RNA - urinary bladder [nTPM]":"11.9","Tissue RNA - vagina [nTPM]":"11.1","Tissue RNA - white matter [nTPM]":"10.8","Cell RNA - A-431 [nTPM]":"18.8","Cell RNA - A549 [nTPM]":"16.0","Cell RNA - AF22 [nTPM]":"9.6","Cell RNA - AN3-CA [nTPM]":"33.5","Cell RNA - ASC diff [nTPM]":"8.8","Cell RNA - ASC TERT1 [nTPM]":"8.9","Cell RNA - BEWO [nTPM]":"20.4","Cell RNA - BJ [nTPM]":"10.9","Cell RNA - BJ hTERT+ [nTPM]":"7.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.6","Cell RNA - CACO-2 [nTPM]":"16.3","Cell RNA - CAPAN-2 [nTPM]":"16.0","Cell RNA - Daudi [nTPM]":"6.9","Cell RNA - EFO-21 [nTPM]":"15.9","Cell RNA - fHDF\/TERT166 [nTPM]":"9.7","Cell RNA - GAMG [nTPM]":"14.3","Cell RNA - HaCaT [nTPM]":"15.0","Cell RNA - HAP1 [nTPM]":"10.6","Cell RNA - HBEC3-KT [nTPM]":"18.0","Cell RNA - HBF TERT88 [nTPM]":"4.9","Cell RNA - HDLM-2 [nTPM]":"18.1","Cell RNA - HEK 293 [nTPM]":"23.6","Cell RNA - HEL [nTPM]":"7.3","Cell RNA - HeLa [nTPM]":"15.6","Cell RNA - Hep G2 [nTPM]":"15.5","Cell RNA - HHSteC [nTPM]":"14.7","Cell RNA - HL-60 [nTPM]":"20.8","Cell RNA - HMC-1 [nTPM]":"12.4","Cell RNA - HSkMC [nTPM]":"8.2","Cell RNA - hTCEpi [nTPM]":"15.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.9","Cell RNA - hTERT-HME1 [nTPM]":"8.6","Cell RNA - hTERT-RPE1 [nTPM]":"6.1","Cell RNA - HUVEC TERT2 [nTPM]":"11.9","Cell RNA - JURKAT [nTPM]":"13.7","Cell RNA - K-562 [nTPM]":"14.7","Cell RNA - Karpas-707 [nTPM]":"11.8","Cell RNA - LHCN-M2 [nTPM]":"8.6","Cell RNA - MCF7 [nTPM]":"58.3","Cell RNA - MOLT-4 [nTPM]":"15.3","Cell RNA - NB-4 [nTPM]":"24.4","Cell RNA - NTERA-2 [nTPM]":"11.2","Cell RNA - OE19 [nTPM]":"9.5","Cell RNA - PC-3 [nTPM]":"23.2","Cell RNA - REH [nTPM]":"22.0","Cell RNA - RH-30 [nTPM]":"15.6","Cell RNA - RPMI-8226 [nTPM]":"30.1","Cell RNA - RPTEC TERT1 [nTPM]":"9.4","Cell RNA - RT4 [nTPM]":"9.4","Cell RNA - SCLC-21H [nTPM]":"11.4","Cell RNA - SH-SY5Y [nTPM]":"8.8","Cell RNA - SiHa [nTPM]":"16.7","Cell RNA - SK-BR-3 [nTPM]":"19.4","Cell RNA - SK-MEL-30 [nTPM]":"15.0","Cell RNA - SuSa [nTPM]":"9.8","Cell RNA - T-47d [nTPM]":"30.2","Cell RNA - THP-1 [nTPM]":"20.2","Cell RNA - TIME [nTPM]":"13.3","Cell RNA - U-138 MG [nTPM]":"15.4","Cell RNA - U-2 OS [nTPM]":"16.5","Cell RNA - U-2197 [nTPM]":"19.2","Cell RNA - U-251 MG [nTPM]":"11.6","Cell RNA - U-266\/70 [nTPM]":"21.2","Cell RNA - U-266\/84 [nTPM]":"12.6","Cell RNA - U-698 [nTPM]":"12.5","Cell RNA - U-87 MG [nTPM]":"16.8","Cell RNA - U-937 [nTPM]":"38.5","Cell RNA - WM-115 [nTPM]":"12.3","Blood RNA - basophil [nTPM]":"8.6","Blood RNA - classical monocyte [nTPM]":"37.0","Blood RNA - eosinophil [nTPM]":"23.8","Blood RNA - gdT-cell [nTPM]":"18.3","Blood RNA - intermediate monocyte [nTPM]":"30.9","Blood RNA - MAIT T-cell [nTPM]":"20.1","Blood RNA - memory B-cell [nTPM]":"18.9","Blood RNA - memory CD4 T-cell [nTPM]":"18.8","Blood RNA - memory CD8 T-cell [nTPM]":"21.3","Blood RNA - myeloid DC [nTPM]":"38.2","Blood RNA - naive B-cell [nTPM]":"16.8","Blood RNA - naive CD4 T-cell [nTPM]":"16.7","Blood RNA - naive CD8 T-cell [nTPM]":"19.6","Blood RNA - neutrophil [nTPM]":"2.8","Blood RNA - NK-cell [nTPM]":"10.8","Blood RNA - non-classical monocyte [nTPM]":"27.1","Blood RNA - plasmacytoid DC [nTPM]":"15.1","Blood RNA - T-reg [nTPM]":"21.8","Blood RNA - total PBMC [nTPM]":"28.0","Brain RNA - amygdala [nTPM]":"9.4","Brain RNA - basal ganglia [nTPM]":"10.0","Brain RNA - cerebellum [nTPM]":"9.9","Brain RNA - cerebral cortex [nTPM]":"10.8","Brain RNA - hippocampal formation [nTPM]":"9.4","Brain RNA - hypothalamus [nTPM]":"9.2","Brain RNA - medulla oblongata [nTPM]":"10.8","Brain RNA - midbrain [nTPM]":"9.4","Brain RNA - pons [nTPM]":"10.1","Brain RNA - spinal cord [nTPM]":"9.6","Brain RNA - thalamus [nTPM]":"10.0","Brain RNA - white matter [nTPM]":"10.8","Single Cell Type RNA - Adipocytes [nTPM]":"8.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.4","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"15.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"11.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"12.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.2","Single Cell Type RNA - dendritic cells [nTPM]":"11.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"13.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.6","Single Cell Type RNA - Endothelial cells [nTPM]":"7.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"8.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.8","Single Cell Type RNA - Fibroblasts [nTPM]":"7.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.9","Single Cell Type RNA - granulocytes [nTPM]":"11.4","Single Cell Type RNA - Granulosa cells [nTPM]":"8.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"7.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"32.0","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.2","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"14.4","Single Cell Type RNA - Langerhans cells [nTPM]":"11.9","Single Cell Type RNA - Late spermatids [nTPM]":"0.4","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"13.8","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"18.0","Single Cell Type RNA - Muller glia cells [nTPM]":"9.9","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.6","Single Cell Type RNA - Paneth cells [nTPM]":"7.6","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"10.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.2","Single Cell Type RNA - T-cells [nTPM]":"13.3","Single Cell Type RNA - Theca cells [nTPM]":"11.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.7","Single Cell Type RNA - Urothelial cells [nTPM]":"8.3"},{"Gene":"CCDC47","Gene synonym":["GK001"],"Ensembl":"ENSG00000108588","Gene description":"Coiled-coil domain containing 47","Uniprot":["Q96A33"],"Chromosome":"17","Position":"63745255-63776351","Protein class":["Disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029674","HPA072573","HPA075958"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA029674":"AB_10602703","HPA072573":"AB_2686535","HPA075958":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.17e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Tissue RNA - adipose tissue [nTPM]":"57.9","Tissue RNA - adrenal gland [nTPM]":"67.3","Tissue RNA - amygdala [nTPM]":"24.3","Tissue RNA - appendix [nTPM]":"42.5","Tissue RNA - basal ganglia [nTPM]":"33.6","Tissue RNA - bone marrow [nTPM]":"29.0","Tissue RNA - breast [nTPM]":"57.1","Tissue RNA - cerebellum [nTPM]":"28.8","Tissue RNA - cerebral cortex [nTPM]":"39.2","Tissue RNA - cervix [nTPM]":"47.7","Tissue RNA - choroid plexus [nTPM]":"46.9","Tissue RNA - colon [nTPM]":"83.4","Tissue RNA - duodenum [nTPM]":"87.1","Tissue RNA - endometrium 1 [nTPM]":"39.1","Tissue RNA - epididymis [nTPM]":"53.7","Tissue RNA - esophagus [nTPM]":"52.6","Tissue RNA - fallopian tube [nTPM]":"43.9","Tissue RNA - gallbladder [nTPM]":"48.2","Tissue RNA - heart muscle [nTPM]":"65.5","Tissue RNA - hippocampal formation [nTPM]":"29.3","Tissue RNA - hypothalamus [nTPM]":"27.9","Tissue RNA - kidney [nTPM]":"72.0","Tissue RNA - liver [nTPM]":"102.2","Tissue RNA - lung [nTPM]":"52.7","Tissue RNA - lymph node [nTPM]":"33.5","Tissue RNA - medulla oblongata [nTPM]":"28.8","Tissue RNA - midbrain [nTPM]":"27.4","Tissue RNA - ovary [nTPM]":"35.3","Tissue RNA - pancreas [nTPM]":"59.8","Tissue RNA - parathyroid gland [nTPM]":"84.6","Tissue RNA - pituitary gland [nTPM]":"21.9","Tissue RNA - placenta [nTPM]":"54.8","Tissue RNA - pons [nTPM]":"29.9","Tissue RNA - prostate [nTPM]":"60.2","Tissue RNA - rectum [nTPM]":"80.6","Tissue RNA - retina [nTPM]":"46.9","Tissue RNA - salivary gland [nTPM]":"62.4","Tissue RNA - seminal vesicle [nTPM]":"52.0","Tissue RNA - skeletal muscle [nTPM]":"115.3","Tissue RNA - skin 1 [nTPM]":"52.2","Tissue RNA - small intestine [nTPM]":"78.2","Tissue RNA - smooth muscle [nTPM]":"42.1","Tissue RNA - spinal cord [nTPM]":"30.1","Tissue RNA - spleen [nTPM]":"35.6","Tissue RNA - stomach 1 [nTPM]":"78.5","Tissue RNA - testis [nTPM]":"32.1","Tissue RNA - thalamus [nTPM]":"26.0","Tissue RNA - thymus [nTPM]":"29.9","Tissue RNA - thyroid gland [nTPM]":"62.0","Tissue RNA - tongue [nTPM]":"83.7","Tissue RNA - tonsil [nTPM]":"40.5","Tissue RNA - urinary bladder [nTPM]":"58.5","Tissue RNA - vagina [nTPM]":"29.3","Tissue RNA - white matter [nTPM]":"34.3","Cell RNA - A-431 [nTPM]":"143.3","Cell RNA - A549 [nTPM]":"133.8","Cell RNA - AF22 [nTPM]":"81.4","Cell RNA - AN3-CA [nTPM]":"71.9","Cell RNA - ASC diff [nTPM]":"112.4","Cell RNA - ASC TERT1 [nTPM]":"74.0","Cell RNA - BEWO [nTPM]":"158.0","Cell RNA - BJ [nTPM]":"141.9","Cell RNA - BJ hTERT+ [nTPM]":"92.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"96.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"112.4","Cell RNA - CACO-2 [nTPM]":"118.7","Cell RNA - CAPAN-2 [nTPM]":"127.0","Cell RNA - Daudi [nTPM]":"112.9","Cell RNA - EFO-21 [nTPM]":"74.3","Cell RNA - fHDF\/TERT166 [nTPM]":"100.9","Cell RNA - GAMG [nTPM]":"110.8","Cell RNA - HaCaT [nTPM]":"114.3","Cell RNA - HAP1 [nTPM]":"99.3","Cell RNA - HBEC3-KT [nTPM]":"88.1","Cell RNA - HBF TERT88 [nTPM]":"168.9","Cell RNA - HDLM-2 [nTPM]":"39.4","Cell RNA - HEK 293 [nTPM]":"101.2","Cell RNA - HEL [nTPM]":"160.9","Cell RNA - HeLa [nTPM]":"106.4","Cell RNA - Hep G2 [nTPM]":"117.3","Cell RNA - HHSteC [nTPM]":"107.6","Cell RNA - HL-60 [nTPM]":"129.9","Cell RNA - HMC-1 [nTPM]":"81.3","Cell RNA - HSkMC [nTPM]":"78.5","Cell RNA - hTCEpi [nTPM]":"121.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"132.4","Cell RNA - hTERT-HME1 [nTPM]":"113.2","Cell RNA - hTERT-RPE1 [nTPM]":"67.9","Cell RNA - HUVEC TERT2 [nTPM]":"81.3","Cell RNA - JURKAT [nTPM]":"55.3","Cell RNA - K-562 [nTPM]":"183.5","Cell RNA - Karpas-707 [nTPM]":"95.5","Cell RNA - LHCN-M2 [nTPM]":"79.4","Cell RNA - MCF7 [nTPM]":"116.1","Cell RNA - MOLT-4 [nTPM]":"100.5","Cell RNA - NB-4 [nTPM]":"48.1","Cell RNA - NTERA-2 [nTPM]":"70.8","Cell RNA - OE19 [nTPM]":"179.4","Cell RNA - PC-3 [nTPM]":"134.0","Cell RNA - REH [nTPM]":"92.2","Cell RNA - RH-30 [nTPM]":"157.9","Cell RNA - RPMI-8226 [nTPM]":"154.6","Cell RNA - RPTEC TERT1 [nTPM]":"115.3","Cell RNA - RT4 [nTPM]":"161.1","Cell RNA - SCLC-21H [nTPM]":"74.2","Cell RNA - SH-SY5Y [nTPM]":"101.5","Cell RNA - SiHa [nTPM]":"95.2","Cell RNA - SK-BR-3 [nTPM]":"242.8","Cell RNA - SK-MEL-30 [nTPM]":"120.3","Cell RNA - SuSa [nTPM]":"103.0","Cell RNA - T-47d [nTPM]":"159.8","Cell RNA - THP-1 [nTPM]":"70.4","Cell RNA - TIME [nTPM]":"104.0","Cell RNA - U-138 MG [nTPM]":"177.6","Cell RNA - U-2 OS [nTPM]":"112.9","Cell RNA - U-2197 [nTPM]":"130.6","Cell RNA - U-251 MG [nTPM]":"166.0","Cell RNA - U-266\/70 [nTPM]":"93.9","Cell RNA - U-266\/84 [nTPM]":"119.9","Cell RNA - U-698 [nTPM]":"112.8","Cell RNA - U-87 MG [nTPM]":"103.9","Cell RNA - U-937 [nTPM]":"81.4","Cell RNA - WM-115 [nTPM]":"147.3","Blood RNA - basophil [nTPM]":"53.2","Blood RNA - classical monocyte [nTPM]":"59.7","Blood RNA - eosinophil [nTPM]":"75.6","Blood RNA - gdT-cell [nTPM]":"40.7","Blood RNA - intermediate monocyte [nTPM]":"61.5","Blood RNA - MAIT T-cell [nTPM]":"47.9","Blood RNA - memory B-cell [nTPM]":"38.4","Blood RNA - memory CD4 T-cell [nTPM]":"39.8","Blood RNA - memory CD8 T-cell [nTPM]":"37.9","Blood RNA - myeloid DC [nTPM]":"82.5","Blood RNA - naive B-cell [nTPM]":"31.7","Blood RNA - naive CD4 T-cell [nTPM]":"41.1","Blood RNA - naive CD8 T-cell [nTPM]":"36.2","Blood RNA - neutrophil [nTPM]":"47.6","Blood RNA - NK-cell [nTPM]":"43.4","Blood RNA - non-classical monocyte [nTPM]":"65.9","Blood RNA - plasmacytoid DC [nTPM]":"54.7","Blood RNA - T-reg [nTPM]":"49.0","Blood RNA - total PBMC [nTPM]":"52.0","Brain RNA - amygdala [nTPM]":"24.3","Brain RNA - basal ganglia [nTPM]":"33.6","Brain RNA - cerebellum [nTPM]":"28.8","Brain RNA - cerebral cortex [nTPM]":"39.2","Brain RNA - hippocampal formation [nTPM]":"29.3","Brain RNA - hypothalamus [nTPM]":"27.9","Brain RNA - medulla oblongata [nTPM]":"28.8","Brain RNA - midbrain [nTPM]":"27.4","Brain RNA - pons [nTPM]":"29.9","Brain RNA - spinal cord [nTPM]":"30.1","Brain RNA - thalamus [nTPM]":"26.0","Brain RNA - white matter [nTPM]":"34.3","Single Cell Type RNA - Adipocytes [nTPM]":"96.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"144.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"122.2","Single Cell Type RNA - Astrocytes [nTPM]":"16.3","Single Cell Type RNA - B-cells [nTPM]":"46.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"100.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"108.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"95.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"98.4","Single Cell Type RNA - Bipolar cells [nTPM]":"40.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"65.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"53.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"129.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"72.9","Single Cell Type RNA - Club cells [nTPM]":"128.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"60.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"111.1","Single Cell Type RNA - dendritic cells [nTPM]":"59.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"99.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"115.3","Single Cell Type RNA - Early spermatids [nTPM]":"17.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"80.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"73.9","Single Cell Type RNA - Endothelial cells [nTPM]":"83.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"52.2","Single Cell Type RNA - Erythroid cells [nTPM]":"76.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"26.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"105.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"98.3","Single Cell Type RNA - Fibroblasts [nTPM]":"85.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"65.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"126.0","Single Cell Type RNA - granulocytes [nTPM]":"45.5","Single Cell Type RNA - Granulosa cells [nTPM]":"31.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"68.2","Single Cell Type RNA - Hepatocytes [nTPM]":"96.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"57.5","Single Cell Type RNA - Horizontal cells [nTPM]":"57.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"95.1","Single Cell Type RNA - Ionocytes [nTPM]":"83.4","Single Cell Type RNA - Kupffer cells [nTPM]":"56.9","Single Cell Type RNA - Langerhans cells [nTPM]":"58.3","Single Cell Type RNA - Late spermatids [nTPM]":"11.5","Single Cell Type RNA - Leydig cells [nTPM]":"47.8","Single Cell Type RNA - Macrophages [nTPM]":"60.7","Single Cell Type RNA - Melanocytes [nTPM]":"39.2","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"52.9","Single Cell Type RNA - Muller glia cells [nTPM]":"55.3","Single Cell Type RNA - NK-cells [nTPM]":"25.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"25.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"92.0","Single Cell Type RNA - Paneth cells [nTPM]":"62.6","Single Cell Type RNA - Peritubular cells [nTPM]":"56.1","Single Cell Type RNA - Plasma cells [nTPM]":"56.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"89.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"87.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"32.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"83.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"27.9","Single Cell Type RNA - Sertoli cells [nTPM]":"72.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"117.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"92.1","Single Cell Type RNA - Spermatocytes [nTPM]":"82.0","Single Cell Type RNA - Spermatogonia [nTPM]":"44.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"90.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"90.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"144.1","Single Cell Type RNA - T-cells [nTPM]":"42.7","Single Cell Type RNA - Theca cells [nTPM]":"53.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"110.5","Single Cell Type RNA - Urothelial cells [nTPM]":"83.3"},{"Gene":"CD151","Gene synonym":["PETA-3","RAPH","SFA-1","TSPAN24"],"Ensembl":"ENSG00000177697","Gene description":"CD151 molecule (Raph blood group)","Uniprot":["P48509"],"Chromosome":"11","Position":"832887-839831","Protein class":["Blood group antigen proteins","CD markers","Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":["Blood group antigen"],"Disease involvement":["Deafness","Epidermolysis bullosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"716.2","Exocrine glandular cells":"636.7","Pancreatic endocrine cells":"736.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002428","HPA011906"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 1: Pancreatic cells - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002428":"AB_564129","HPA011906":"AB_1846245"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.58e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.46e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.92e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"},"Tissue RNA - adipose tissue [nTPM]":"332.4","Tissue RNA - adrenal gland [nTPM]":"159.5","Tissue RNA - amygdala [nTPM]":"54.0","Tissue RNA - appendix [nTPM]":"79.7","Tissue RNA - basal ganglia [nTPM]":"53.5","Tissue RNA - bone marrow [nTPM]":"25.0","Tissue RNA - breast [nTPM]":"277.8","Tissue RNA - cerebellum [nTPM]":"52.5","Tissue RNA - cerebral cortex [nTPM]":"67.6","Tissue RNA - cervix [nTPM]":"181.6","Tissue RNA - choroid plexus [nTPM]":"66.1","Tissue RNA - colon [nTPM]":"219.7","Tissue RNA - duodenum [nTPM]":"140.6","Tissue RNA - endometrium 1 [nTPM]":"264.6","Tissue RNA - epididymis [nTPM]":"103.0","Tissue RNA - esophagus [nTPM]":"97.5","Tissue RNA - fallopian tube [nTPM]":"184.3","Tissue RNA - gallbladder [nTPM]":"132.4","Tissue RNA - heart muscle [nTPM]":"345.8","Tissue RNA - hippocampal formation [nTPM]":"54.2","Tissue RNA - hypothalamus [nTPM]":"65.3","Tissue RNA - kidney [nTPM]":"194.3","Tissue RNA - liver [nTPM]":"145.3","Tissue RNA - lung [nTPM]":"240.1","Tissue RNA - lymph node [nTPM]":"35.4","Tissue RNA - medulla oblongata [nTPM]":"64.5","Tissue RNA - midbrain [nTPM]":"57.4","Tissue RNA - ovary [nTPM]":"116.2","Tissue RNA - pancreas [nTPM]":"278.3","Tissue RNA - parathyroid gland [nTPM]":"85.9","Tissue RNA - pituitary gland [nTPM]":"81.1","Tissue RNA - placenta [nTPM]":"110.1","Tissue RNA - pons [nTPM]":"60.5","Tissue RNA - prostate [nTPM]":"182.9","Tissue RNA - rectum [nTPM]":"99.8","Tissue RNA - retina [nTPM]":"9.6","Tissue RNA - salivary gland [nTPM]":"243.5","Tissue RNA - seminal vesicle [nTPM]":"194.2","Tissue RNA - skeletal muscle [nTPM]":"113.1","Tissue RNA - skin 1 [nTPM]":"107.0","Tissue RNA - small intestine [nTPM]":"149.4","Tissue RNA - smooth muscle [nTPM]":"255.2","Tissue RNA - spinal cord [nTPM]":"58.3","Tissue RNA - spleen [nTPM]":"94.8","Tissue RNA - stomach 1 [nTPM]":"187.3","Tissue RNA - testis [nTPM]":"44.8","Tissue RNA - thalamus [nTPM]":"58.6","Tissue RNA - thymus [nTPM]":"15.0","Tissue RNA - thyroid gland [nTPM]":"133.5","Tissue RNA - tongue [nTPM]":"77.0","Tissue RNA - tonsil [nTPM]":"30.6","Tissue RNA - urinary bladder [nTPM]":"203.1","Tissue RNA - vagina [nTPM]":"151.3","Tissue RNA - white matter [nTPM]":"58.0","Cell RNA - A-431 [nTPM]":"380.0","Cell RNA - A549 [nTPM]":"475.3","Cell RNA - AF22 [nTPM]":"71.8","Cell RNA - AN3-CA [nTPM]":"256.3","Cell RNA - ASC diff [nTPM]":"1088.7","Cell RNA - ASC TERT1 [nTPM]":"422.8","Cell RNA - BEWO [nTPM]":"110.4","Cell RNA - BJ [nTPM]":"587.1","Cell RNA - BJ hTERT+ [nTPM]":"400.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"285.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"241.2","Cell RNA - CACO-2 [nTPM]":"252.6","Cell RNA - CAPAN-2 [nTPM]":"677.2","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"224.0","Cell RNA - fHDF\/TERT166 [nTPM]":"943.5","Cell RNA - GAMG [nTPM]":"388.4","Cell RNA - HaCaT [nTPM]":"358.4","Cell RNA - HAP1 [nTPM]":"71.1","Cell RNA - HBEC3-KT [nTPM]":"498.4","Cell RNA - HBF TERT88 [nTPM]":"96.1","Cell RNA - HDLM-2 [nTPM]":"135.0","Cell RNA - HEK 293 [nTPM]":"236.6","Cell RNA - HEL [nTPM]":"112.8","Cell RNA - HeLa [nTPM]":"139.1","Cell RNA - Hep G2 [nTPM]":"193.4","Cell RNA - HHSteC [nTPM]":"366.7","Cell RNA - HL-60 [nTPM]":"90.2","Cell RNA - HMC-1 [nTPM]":"157.4","Cell RNA - HSkMC [nTPM]":"388.6","Cell RNA - hTCEpi [nTPM]":"328.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"164.5","Cell RNA - hTERT-HME1 [nTPM]":"367.8","Cell RNA - hTERT-RPE1 [nTPM]":"1089.2","Cell RNA - HUVEC TERT2 [nTPM]":"348.8","Cell RNA - JURKAT [nTPM]":"16.4","Cell RNA - K-562 [nTPM]":"135.1","Cell RNA - Karpas-707 [nTPM]":"56.3","Cell RNA - LHCN-M2 [nTPM]":"485.9","Cell RNA - MCF7 [nTPM]":"196.1","Cell RNA - MOLT-4 [nTPM]":"1.9","Cell RNA - NB-4 [nTPM]":"99.5","Cell RNA - NTERA-2 [nTPM]":"48.0","Cell RNA - OE19 [nTPM]":"232.9","Cell RNA - PC-3 [nTPM]":"569.4","Cell RNA - REH [nTPM]":"20.0","Cell RNA - RH-30 [nTPM]":"173.7","Cell RNA - RPMI-8226 [nTPM]":"106.4","Cell RNA - RPTEC TERT1 [nTPM]":"642.8","Cell RNA - RT4 [nTPM]":"102.1","Cell RNA - SCLC-21H [nTPM]":"99.5","Cell RNA - SH-SY5Y [nTPM]":"111.8","Cell RNA - SiHa [nTPM]":"578.9","Cell RNA - SK-BR-3 [nTPM]":"371.5","Cell RNA - SK-MEL-30 [nTPM]":"121.5","Cell RNA - SuSa [nTPM]":"81.6","Cell RNA - T-47d [nTPM]":"145.8","Cell RNA - THP-1 [nTPM]":"102.4","Cell RNA - TIME [nTPM]":"600.0","Cell RNA - U-138 MG [nTPM]":"462.6","Cell RNA - U-2 OS [nTPM]":"209.3","Cell RNA - U-2197 [nTPM]":"147.5","Cell RNA - U-251 MG [nTPM]":"352.9","Cell RNA - U-266\/70 [nTPM]":"62.0","Cell RNA - U-266\/84 [nTPM]":"66.5","Cell RNA - U-698 [nTPM]":"4.5","Cell RNA - U-87 MG [nTPM]":"437.5","Cell RNA - U-937 [nTPM]":"89.7","Cell RNA - WM-115 [nTPM]":"265.8","Blood RNA - basophil [nTPM]":"24.6","Blood RNA - classical monocyte [nTPM]":"19.1","Blood RNA - eosinophil [nTPM]":"15.2","Blood RNA - gdT-cell [nTPM]":"5.7","Blood RNA - intermediate monocyte [nTPM]":"19.3","Blood RNA - MAIT T-cell [nTPM]":"6.8","Blood RNA - memory B-cell [nTPM]":"3.0","Blood RNA - memory CD4 T-cell [nTPM]":"4.7","Blood RNA - memory CD8 T-cell [nTPM]":"5.0","Blood RNA - myeloid DC [nTPM]":"11.9","Blood RNA - naive B-cell [nTPM]":"2.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.9","Blood RNA - naive CD8 T-cell [nTPM]":"3.0","Blood RNA - neutrophil [nTPM]":"7.3","Blood RNA - NK-cell [nTPM]":"8.2","Blood RNA - non-classical monocyte [nTPM]":"24.1","Blood RNA - plasmacytoid DC [nTPM]":"1.8","Blood RNA - T-reg [nTPM]":"2.9","Blood RNA - total PBMC [nTPM]":"10.8","Brain RNA - amygdala [nTPM]":"54.0","Brain RNA - basal ganglia [nTPM]":"53.5","Brain RNA - cerebellum [nTPM]":"52.5","Brain RNA - cerebral cortex [nTPM]":"67.6","Brain RNA - hippocampal formation [nTPM]":"54.2","Brain RNA - hypothalamus [nTPM]":"65.3","Brain RNA - medulla oblongata [nTPM]":"64.5","Brain RNA - midbrain [nTPM]":"57.4","Brain RNA - pons [nTPM]":"60.5","Brain RNA - spinal cord [nTPM]":"58.3","Brain RNA - thalamus [nTPM]":"58.6","Brain RNA - white matter [nTPM]":"58.0","Single Cell Type RNA - Adipocytes [nTPM]":"294.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"208.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"79.1","Single Cell Type RNA - Astrocytes [nTPM]":"13.1","Single Cell Type RNA - B-cells [nTPM]":"12.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"70.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"143.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"328.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"60.9","Single Cell Type RNA - Bipolar cells [nTPM]":"16.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"180.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"203.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"180.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"133.0","Single Cell Type RNA - Club cells [nTPM]":"159.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"248.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"222.6","Single Cell Type RNA - dendritic cells [nTPM]":"15.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"542.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"716.2","Single Cell Type RNA - Early spermatids [nTPM]":"2.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"60.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"114.6","Single Cell Type RNA - Endothelial cells [nTPM]":"214.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"127.6","Single Cell Type RNA - Erythroid cells [nTPM]":"28.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"636.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"423.8","Single Cell Type RNA - Fibroblasts [nTPM]":"173.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"236.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"143.7","Single Cell Type RNA - granulocytes [nTPM]":"81.3","Single Cell Type RNA - Granulosa cells [nTPM]":"103.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"265.2","Single Cell Type RNA - Hepatocytes [nTPM]":"54.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"130.0","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"388.5","Single Cell Type RNA - Ionocytes [nTPM]":"138.4","Single Cell Type RNA - Kupffer cells [nTPM]":"59.3","Single Cell Type RNA - Langerhans cells [nTPM]":"70.4","Single Cell Type RNA - Late spermatids [nTPM]":"11.3","Single Cell Type RNA - Leydig cells [nTPM]":"123.6","Single Cell Type RNA - Macrophages [nTPM]":"81.8","Single Cell Type RNA - Melanocytes [nTPM]":"128.1","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"75.6","Single Cell Type RNA - Muller glia cells [nTPM]":"94.8","Single Cell Type RNA - NK-cells [nTPM]":"23.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"736.6","Single Cell Type RNA - Paneth cells [nTPM]":"477.9","Single Cell Type RNA - Peritubular cells [nTPM]":"283.2","Single Cell Type RNA - Plasma cells [nTPM]":"26.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"307.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"440.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"124.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"52.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.0","Single Cell Type RNA - Sertoli cells [nTPM]":"210.4","Single Cell Type RNA - Skeletal myocytes [nTPM]":"96.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"310.3","Single Cell Type RNA - Spermatocytes [nTPM]":"5.6","Single Cell Type RNA - Spermatogonia [nTPM]":"13.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"73.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"54.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"185.7","Single Cell Type RNA - T-cells [nTPM]":"29.7","Single Cell Type RNA - Theca cells [nTPM]":"61.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"289.8","Single Cell Type RNA - Urothelial cells [nTPM]":"199.6"},{"Gene":"CD2AP","Gene synonym":["CMS"],"Ensembl":"ENSG00000198087","Gene description":"CD2 associated protein","Uniprot":["Q9Y5K6"],"Chromosome":"6","Position":"47477789-47627263","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Cell cycle","Cell division","Mitosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"204.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"9.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003267","HPA003326","CAB004352"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Centriolar satellite"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"58000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Centriolar satellite"],"Antibody RRID":{"CAB004352":"AB_627009","HPA003267":"AB_1078458","HPA003326":"AB_1078457"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.53e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.57e-5"},"Tissue RNA - adipose tissue [nTPM]":"14.0","Tissue RNA - adrenal gland [nTPM]":"10.5","Tissue RNA - amygdala [nTPM]":"3.4","Tissue RNA - appendix [nTPM]":"15.0","Tissue RNA - basal ganglia [nTPM]":"3.4","Tissue RNA - bone marrow [nTPM]":"14.3","Tissue RNA - breast [nTPM]":"17.8","Tissue RNA - cerebellum [nTPM]":"6.3","Tissue RNA - cerebral cortex [nTPM]":"4.6","Tissue RNA - cervix [nTPM]":"18.1","Tissue RNA - choroid plexus [nTPM]":"8.8","Tissue RNA - colon [nTPM]":"40.0","Tissue RNA - duodenum [nTPM]":"56.9","Tissue RNA - endometrium 1 [nTPM]":"12.0","Tissue RNA - epididymis [nTPM]":"13.2","Tissue RNA - esophagus [nTPM]":"19.2","Tissue RNA - fallopian tube [nTPM]":"14.1","Tissue RNA - gallbladder [nTPM]":"15.0","Tissue RNA - heart muscle [nTPM]":"7.7","Tissue RNA - hippocampal formation [nTPM]":"2.7","Tissue RNA - hypothalamus [nTPM]":"3.8","Tissue RNA - kidney [nTPM]":"34.1","Tissue RNA - liver [nTPM]":"20.2","Tissue RNA - lung [nTPM]":"17.1","Tissue RNA - lymph node [nTPM]":"15.9","Tissue RNA - medulla oblongata [nTPM]":"4.3","Tissue RNA - midbrain [nTPM]":"3.9","Tissue RNA - ovary [nTPM]":"6.4","Tissue RNA - pancreas [nTPM]":"20.2","Tissue RNA - parathyroid gland [nTPM]":"35.6","Tissue RNA - pituitary gland [nTPM]":"6.0","Tissue RNA - placenta [nTPM]":"21.6","Tissue RNA - pons [nTPM]":"4.7","Tissue RNA - prostate [nTPM]":"19.7","Tissue RNA - rectum [nTPM]":"36.9","Tissue RNA - retina [nTPM]":"6.9","Tissue RNA - salivary gland [nTPM]":"17.0","Tissue RNA - seminal vesicle [nTPM]":"13.5","Tissue RNA - skeletal muscle [nTPM]":"6.9","Tissue RNA - skin 1 [nTPM]":"18.0","Tissue RNA - small intestine [nTPM]":"59.5","Tissue RNA - smooth muscle [nTPM]":"10.9","Tissue RNA - spinal cord [nTPM]":"4.3","Tissue RNA - spleen [nTPM]":"13.7","Tissue RNA - stomach 1 [nTPM]":"40.4","Tissue RNA - testis [nTPM]":"9.4","Tissue RNA - thalamus [nTPM]":"3.9","Tissue RNA - thymus [nTPM]":"34.0","Tissue RNA - thyroid gland [nTPM]":"18.2","Tissue RNA - tongue [nTPM]":"10.3","Tissue RNA - tonsil [nTPM]":"17.4","Tissue RNA - urinary bladder [nTPM]":"30.1","Tissue RNA - vagina [nTPM]":"10.1","Tissue RNA - white matter [nTPM]":"4.6","Cell RNA - A-431 [nTPM]":"58.0","Cell RNA - A549 [nTPM]":"22.5","Cell RNA - AF22 [nTPM]":"6.9","Cell RNA - AN3-CA [nTPM]":"14.3","Cell RNA - ASC diff [nTPM]":"9.4","Cell RNA - ASC TERT1 [nTPM]":"13.6","Cell RNA - BEWO [nTPM]":"54.8","Cell RNA - BJ [nTPM]":"13.9","Cell RNA - BJ hTERT+ [nTPM]":"16.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.3","Cell RNA - CACO-2 [nTPM]":"37.3","Cell RNA - CAPAN-2 [nTPM]":"39.9","Cell RNA - Daudi [nTPM]":"74.5","Cell RNA - EFO-21 [nTPM]":"56.9","Cell RNA - fHDF\/TERT166 [nTPM]":"18.2","Cell RNA - GAMG [nTPM]":"24.0","Cell RNA - HaCaT [nTPM]":"21.2","Cell RNA - HAP1 [nTPM]":"23.0","Cell RNA - HBEC3-KT [nTPM]":"34.7","Cell RNA - HBF TERT88 [nTPM]":"29.9","Cell RNA - HDLM-2 [nTPM]":"29.9","Cell RNA - HEK 293 [nTPM]":"37.2","Cell RNA - HEL [nTPM]":"41.3","Cell RNA - HeLa [nTPM]":"18.4","Cell RNA - Hep G2 [nTPM]":"33.6","Cell RNA - HHSteC [nTPM]":"12.5","Cell RNA - HL-60 [nTPM]":"23.3","Cell RNA - HMC-1 [nTPM]":"15.4","Cell RNA - HSkMC [nTPM]":"9.7","Cell RNA - hTCEpi [nTPM]":"32.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"17.7","Cell RNA - hTERT-HME1 [nTPM]":"25.5","Cell RNA - hTERT-RPE1 [nTPM]":"35.7","Cell RNA - HUVEC TERT2 [nTPM]":"30.1","Cell RNA - JURKAT [nTPM]":"24.4","Cell RNA - K-562 [nTPM]":"73.5","Cell RNA - Karpas-707 [nTPM]":"23.2","Cell RNA - LHCN-M2 [nTPM]":"16.9","Cell RNA - MCF7 [nTPM]":"18.2","Cell RNA - MOLT-4 [nTPM]":"44.6","Cell RNA - NB-4 [nTPM]":"8.7","Cell RNA - NTERA-2 [nTPM]":"20.3","Cell RNA - OE19 [nTPM]":"69.6","Cell RNA - PC-3 [nTPM]":"8.1","Cell RNA - REH [nTPM]":"23.6","Cell RNA - RH-30 [nTPM]":"17.6","Cell RNA - RPMI-8226 [nTPM]":"34.1","Cell RNA - RPTEC TERT1 [nTPM]":"115.6","Cell RNA - RT4 [nTPM]":"101.7","Cell RNA - SCLC-21H [nTPM]":"20.9","Cell RNA - SH-SY5Y [nTPM]":"8.1","Cell RNA - SiHa [nTPM]":"27.9","Cell RNA - SK-BR-3 [nTPM]":"36.9","Cell RNA - SK-MEL-30 [nTPM]":"27.7","Cell RNA - SuSa [nTPM]":"31.1","Cell RNA - T-47d [nTPM]":"35.0","Cell RNA - THP-1 [nTPM]":"14.8","Cell RNA - TIME [nTPM]":"36.2","Cell RNA - U-138 MG [nTPM]":"36.9","Cell RNA - U-2 OS [nTPM]":"30.8","Cell RNA - U-2197 [nTPM]":"12.0","Cell RNA - U-251 MG [nTPM]":"39.9","Cell RNA - U-266\/70 [nTPM]":"17.5","Cell RNA - U-266\/84 [nTPM]":"31.3","Cell RNA - U-698 [nTPM]":"52.6","Cell RNA - U-87 MG [nTPM]":"39.4","Cell RNA - U-937 [nTPM]":"12.4","Cell RNA - WM-115 [nTPM]":"19.2","Blood RNA - basophil [nTPM]":"1.8","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"3.2","Blood RNA - gdT-cell [nTPM]":"1.2","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"1.8","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.0","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"1.2","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.9","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"3.1","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"9.9","Blood RNA - T-reg [nTPM]":"0.9","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"3.4","Brain RNA - basal ganglia [nTPM]":"3.4","Brain RNA - cerebellum [nTPM]":"6.3","Brain RNA - cerebral cortex [nTPM]":"4.6","Brain RNA - hippocampal formation [nTPM]":"2.7","Brain RNA - hypothalamus [nTPM]":"3.8","Brain RNA - medulla oblongata [nTPM]":"4.3","Brain RNA - midbrain [nTPM]":"3.9","Brain RNA - pons [nTPM]":"4.7","Brain RNA - spinal cord [nTPM]":"4.3","Brain RNA - thalamus [nTPM]":"3.9","Brain RNA - white matter [nTPM]":"4.6","Single Cell Type RNA - Adipocytes [nTPM]":"81.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"96.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"67.1","Single Cell Type RNA - Astrocytes [nTPM]":"32.0","Single Cell Type RNA - B-cells [nTPM]":"40.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"32.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"52.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"26.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"39.9","Single Cell Type RNA - Bipolar cells [nTPM]":"10.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"40.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"26.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"35.8","Single Cell Type RNA - Club cells [nTPM]":"68.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"71.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"53.0","Single Cell Type RNA - dendritic cells [nTPM]":"96.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"204.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"84.6","Single Cell Type RNA - Early spermatids [nTPM]":"10.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"97.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"25.0","Single Cell Type RNA - Endothelial cells [nTPM]":"56.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"55.8","Single Cell Type RNA - Erythroid cells [nTPM]":"42.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"40.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"98.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.1","Single Cell Type RNA - Fibroblasts [nTPM]":"20.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"101.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"136.7","Single Cell Type RNA - granulocytes [nTPM]":"24.1","Single Cell Type RNA - Granulosa cells [nTPM]":"28.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"37.5","Single Cell Type RNA - Hepatocytes [nTPM]":"24.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.4","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"45.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"97.3","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"26.2","Single Cell Type RNA - Langerhans cells [nTPM]":"12.6","Single Cell Type RNA - Late spermatids [nTPM]":"10.5","Single Cell Type RNA - Leydig cells [nTPM]":"16.8","Single Cell Type RNA - Macrophages [nTPM]":"30.6","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"83.4","Single Cell Type RNA - monocytes [nTPM]":"18.0","Single Cell Type RNA - Muller glia cells [nTPM]":"12.5","Single Cell Type RNA - NK-cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"28.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"30.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"151.3","Single Cell Type RNA - Paneth cells [nTPM]":"114.0","Single Cell Type RNA - Peritubular cells [nTPM]":"10.9","Single Cell Type RNA - Plasma cells [nTPM]":"27.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"89.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"182.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"67.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"60.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.0","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"34.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.8","Single Cell Type RNA - Spermatocytes [nTPM]":"38.9","Single Cell Type RNA - Spermatogonia [nTPM]":"27.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"44.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"41.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"40.9","Single Cell Type RNA - T-cells [nTPM]":"29.4","Single Cell Type RNA - Theca cells [nTPM]":"48.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"68.8","Single Cell Type RNA - Urothelial cells [nTPM]":"143.6"},{"Gene":"CD36","Gene synonym":["FAT","GP3B","GP4","GPIV","SCARB3"],"Ensembl":"ENSG00000135218","Gene description":"CD36 molecule","Uniprot":["P16671"],"Chromosome":"7","Position":"80369575-80679277","Protein class":["Cancer-related genes","CD markers","Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion","Transport"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"1533.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"3219.2","Cardiomyocytes":"623.1","Hofbauer cells":"1369.8","Sertoli cells":"696.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"962.6","intermediate monocyte":"270.6","myeloid DC":"507.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"46","RNA blood lineage specific nTPM":{"dendritic cells":"507.1","monocytes":"962.6"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"ASC diff":"322.6","HEL":"158.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"16.9"},"Antibody":["HPA002018","CAB025866","HPA071026"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5300000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB025866":null,"HPA002018":"AB_1078464","HPA071026":"AB_2732170"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.47e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-3"},"Tissue RNA - adipose tissue [nTPM]":"1533.6","Tissue RNA - adrenal gland [nTPM]":"24.6","Tissue RNA - amygdala [nTPM]":"3.4","Tissue RNA - appendix [nTPM]":"51.7","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"148.2","Tissue RNA - breast [nTPM]":"540.4","Tissue RNA - cerebellum [nTPM]":"1.6","Tissue RNA - cerebral cortex [nTPM]":"2.0","Tissue RNA - cervix [nTPM]":"11.6","Tissue RNA - choroid plexus [nTPM]":"2.7","Tissue RNA - colon [nTPM]":"40.5","Tissue RNA - duodenum [nTPM]":"113.6","Tissue RNA - endometrium 1 [nTPM]":"8.7","Tissue RNA - epididymis [nTPM]":"38.2","Tissue RNA - esophagus [nTPM]":"19.6","Tissue RNA - fallopian tube [nTPM]":"40.5","Tissue RNA - gallbladder [nTPM]":"84.0","Tissue RNA - heart muscle [nTPM]":"540.9","Tissue RNA - hippocampal formation [nTPM]":"2.6","Tissue RNA - hypothalamus [nTPM]":"6.9","Tissue RNA - kidney [nTPM]":"7.0","Tissue RNA - liver [nTPM]":"80.8","Tissue RNA - lung [nTPM]":"131.2","Tissue RNA - lymph node [nTPM]":"18.8","Tissue RNA - medulla oblongata [nTPM]":"22.0","Tissue RNA - midbrain [nTPM]":"21.2","Tissue RNA - ovary [nTPM]":"4.0","Tissue RNA - pancreas [nTPM]":"31.2","Tissue RNA - parathyroid gland [nTPM]":"25.0","Tissue RNA - pituitary gland [nTPM]":"2.0","Tissue RNA - placenta [nTPM]":"413.3","Tissue RNA - pons [nTPM]":"15.7","Tissue RNA - prostate [nTPM]":"5.0","Tissue RNA - rectum [nTPM]":"40.9","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"31.9","Tissue RNA - seminal vesicle [nTPM]":"8.6","Tissue RNA - skeletal muscle [nTPM]":"248.5","Tissue RNA - skin 1 [nTPM]":"28.6","Tissue RNA - small intestine [nTPM]":"119.7","Tissue RNA - smooth muscle [nTPM]":"39.4","Tissue RNA - spinal cord [nTPM]":"14.0","Tissue RNA - spleen [nTPM]":"309.9","Tissue RNA - stomach 1 [nTPM]":"31.2","Tissue RNA - testis [nTPM]":"7.7","Tissue RNA - thalamus [nTPM]":"24.0","Tissue RNA - thymus [nTPM]":"22.1","Tissue RNA - thyroid gland [nTPM]":"69.1","Tissue RNA - tongue [nTPM]":"381.6","Tissue RNA - tonsil [nTPM]":"7.2","Tissue RNA - urinary bladder [nTPM]":"22.2","Tissue RNA - vagina [nTPM]":"13.4","Tissue RNA - white matter [nTPM]":"3.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"1.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"322.6","Cell RNA - ASC TERT1 [nTPM]":"3.3","Cell RNA - BEWO [nTPM]":"0.7","Cell RNA - BJ [nTPM]":"0.9","Cell RNA - BJ hTERT+ [nTPM]":"10.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.6","Cell RNA - fHDF\/TERT166 [nTPM]":"1.4","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"4.3","Cell RNA - HBEC3-KT [nTPM]":"0.5","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.6","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"158.1","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"25.7","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"31.0","Cell RNA - hTCEpi [nTPM]":"12.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"7.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.9","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"5.8","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"1.8","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"1.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.5","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.9","Cell RNA - SH-SY5Y [nTPM]":"1.3","Cell RNA - SiHa [nTPM]":"0.8","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"2.7","Cell RNA - T-47d [nTPM]":"11.1","Cell RNA - THP-1 [nTPM]":"19.3","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.5","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.6","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.8","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"54.3","Cell RNA - WM-115 [nTPM]":"41.8","Blood RNA - basophil [nTPM]":"12.3","Blood RNA - classical monocyte [nTPM]":"962.6","Blood RNA - eosinophil [nTPM]":"3.7","Blood RNA - gdT-cell [nTPM]":"1.9","Blood RNA - intermediate monocyte [nTPM]":"270.6","Blood RNA - MAIT T-cell [nTPM]":"2.1","Blood RNA - memory B-cell [nTPM]":"3.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"507.1","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"15.8","Blood RNA - NK-cell [nTPM]":"5.9","Blood RNA - non-classical monocyte [nTPM]":"72.0","Blood RNA - plasmacytoid DC [nTPM]":"128.3","Blood RNA - T-reg [nTPM]":"1.5","Blood RNA - total PBMC [nTPM]":"692.4","Brain RNA - amygdala [nTPM]":"3.4","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"1.6","Brain RNA - cerebral cortex [nTPM]":"2.0","Brain RNA - hippocampal formation [nTPM]":"2.6","Brain RNA - hypothalamus [nTPM]":"6.9","Brain RNA - medulla oblongata [nTPM]":"22.0","Brain RNA - midbrain [nTPM]":"21.2","Brain RNA - pons [nTPM]":"15.7","Brain RNA - spinal cord [nTPM]":"14.0","Brain RNA - thalamus [nTPM]":"24.0","Brain RNA - white matter [nTPM]":"3.9","Single Cell Type RNA - Adipocytes [nTPM]":"3219.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"63.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"7.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"189.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"623.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"9.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.1","Single Cell Type RNA - dendritic cells [nTPM]":"55.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"11.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.9","Single Cell Type RNA - Endothelial cells [nTPM]":"303.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"419.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.1","Single Cell Type RNA - Fibroblasts [nTPM]":"69.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"38.4","Single Cell Type RNA - granulocytes [nTPM]":"15.2","Single Cell Type RNA - Granulosa cells [nTPM]":"0.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"406.2","Single Cell Type RNA - Hepatocytes [nTPM]":"9.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1369.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.6","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"153.7","Single Cell Type RNA - Langerhans cells [nTPM]":"67.3","Single Cell Type RNA - Late spermatids [nTPM]":"3.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"159.6","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"255.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"4.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"696.8","Single Cell Type RNA - Skeletal myocytes [nTPM]":"33.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"452.1","Single Cell Type RNA - Spermatocytes [nTPM]":"4.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"18.3","Single Cell Type RNA - T-cells [nTPM]":"5.9","Single Cell Type RNA - Theca cells [nTPM]":"1.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"CD74","Gene synonym":["DHLAG"],"Ensembl":"ENSG00000019582","Gene description":"CD74 molecule","Uniprot":["P04233"],"Chromosome":"5","Position":"150400041-150412969","Protein class":["Cancer-related genes","CD markers","Disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Chaperone"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"5258.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"10167.0","Kupffer cells":"5201.6","Langerhans cells":"23363.4","Macrophages":"7290.2","monocytes":"10305.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"11041.2","intermediate monocyte":"15961.1","memory B-cell":"26889.3","myeloid DC":"23750.6","naive B-cell":"27930.3","non-classical monocyte":"8003.3","plasmacytoid DC":"16940.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"B-cells":"27930.3","dendritic cells":"23750.6","monocytes":"15961.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"2171.7","Daudi":"3523.2","HDLM-2":"4787.6","REH":"3026.0","RPMI-8226":"2014.2","U-266\/70":"1443.4","U-698":"1978.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002506","HPA010592","CAB079994"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"210000","Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB002506":"AB_563630","CAB079994":null,"HPA010592":"AB_1078482"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.06e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.53e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Tissue RNA - adipose tissue [nTPM]":"1512.1","Tissue RNA - adrenal gland [nTPM]":"976.5","Tissue RNA - amygdala [nTPM]":"338.1","Tissue RNA - appendix [nTPM]":"2741.2","Tissue RNA - basal ganglia [nTPM]":"301.9","Tissue RNA - bone marrow [nTPM]":"984.3","Tissue RNA - breast [nTPM]":"1157.2","Tissue RNA - cerebellum [nTPM]":"365.5","Tissue RNA - cerebral cortex [nTPM]":"474.4","Tissue RNA - cervix [nTPM]":"1562.8","Tissue RNA - choroid plexus [nTPM]":"429.1","Tissue RNA - colon [nTPM]":"992.3","Tissue RNA - duodenum [nTPM]":"1826.2","Tissue RNA - endometrium 1 [nTPM]":"593.6","Tissue RNA - epididymis [nTPM]":"490.6","Tissue RNA - esophagus [nTPM]":"618.8","Tissue RNA - fallopian tube [nTPM]":"1139.0","Tissue RNA - gallbladder [nTPM]":"1477.9","Tissue RNA - heart muscle [nTPM]":"604.0","Tissue RNA - hippocampal formation [nTPM]":"306.7","Tissue RNA - hypothalamus [nTPM]":"506.8","Tissue RNA - kidney [nTPM]":"1271.1","Tissue RNA - liver [nTPM]":"1142.0","Tissue RNA - lung [nTPM]":"3786.3","Tissue RNA - lymph node [nTPM]":"4995.6","Tissue RNA - medulla oblongata [nTPM]":"598.7","Tissue RNA - midbrain [nTPM]":"431.8","Tissue RNA - ovary [nTPM]":"464.3","Tissue RNA - pancreas [nTPM]":"392.4","Tissue RNA - parathyroid gland [nTPM]":"390.6","Tissue RNA - pituitary gland [nTPM]":"469.3","Tissue RNA - placenta [nTPM]":"305.7","Tissue RNA - pons [nTPM]":"533.4","Tissue RNA - prostate [nTPM]":"556.7","Tissue RNA - rectum [nTPM]":"1155.8","Tissue RNA - retina [nTPM]":"58.1","Tissue RNA - salivary gland [nTPM]":"1999.3","Tissue RNA - seminal vesicle [nTPM]":"911.8","Tissue RNA - skeletal muscle [nTPM]":"307.2","Tissue RNA - skin 1 [nTPM]":"682.4","Tissue RNA - small intestine [nTPM]":"2438.8","Tissue RNA - smooth muscle [nTPM]":"1014.2","Tissue RNA - spinal cord [nTPM]":"514.2","Tissue RNA - spleen [nTPM]":"4897.4","Tissue RNA - stomach 1 [nTPM]":"1511.5","Tissue RNA - testis [nTPM]":"207.5","Tissue RNA - thalamus [nTPM]":"514.4","Tissue RNA - thymus [nTPM]":"2160.2","Tissue RNA - thyroid gland [nTPM]":"853.5","Tissue RNA - tongue [nTPM]":"374.2","Tissue RNA - tonsil [nTPM]":"5258.9","Tissue RNA - urinary bladder [nTPM]":"1557.5","Tissue RNA - vagina [nTPM]":"483.5","Tissue RNA - white matter [nTPM]":"771.8","Cell RNA - A-431 [nTPM]":"35.7","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"1.5","Cell RNA - AN3-CA [nTPM]":"2.4","Cell RNA - ASC diff [nTPM]":"2.3","Cell RNA - ASC TERT1 [nTPM]":"2.5","Cell RNA - BEWO [nTPM]":"11.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.6","Cell RNA - CACO-2 [nTPM]":"443.0","Cell RNA - CAPAN-2 [nTPM]":"2171.7","Cell RNA - Daudi [nTPM]":"3523.2","Cell RNA - EFO-21 [nTPM]":"124.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"9.2","Cell RNA - HaCaT [nTPM]":"9.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"4787.6","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"109.1","Cell RNA - HeLa [nTPM]":"1.2","Cell RNA - Hep G2 [nTPM]":"250.2","Cell RNA - HHSteC [nTPM]":"6.6","Cell RNA - HL-60 [nTPM]":"9.2","Cell RNA - HMC-1 [nTPM]":"6.5","Cell RNA - HSkMC [nTPM]":"24.5","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.8","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"8.0","Cell RNA - Karpas-707 [nTPM]":"1270.7","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"4.2","Cell RNA - NB-4 [nTPM]":"14.0","Cell RNA - NTERA-2 [nTPM]":"5.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"3026.0","Cell RNA - RH-30 [nTPM]":"5.2","Cell RNA - RPMI-8226 [nTPM]":"2014.2","Cell RNA - RPTEC TERT1 [nTPM]":"9.0","Cell RNA - RT4 [nTPM]":"133.5","Cell RNA - SCLC-21H [nTPM]":"5.1","Cell RNA - SH-SY5Y [nTPM]":"8.2","Cell RNA - SiHa [nTPM]":"5.5","Cell RNA - SK-BR-3 [nTPM]":"4.7","Cell RNA - SK-MEL-30 [nTPM]":"94.9","Cell RNA - SuSa [nTPM]":"19.2","Cell RNA - T-47d [nTPM]":"81.2","Cell RNA - THP-1 [nTPM]":"414.4","Cell RNA - TIME [nTPM]":"5.6","Cell RNA - U-138 MG [nTPM]":"10.3","Cell RNA - U-2 OS [nTPM]":"9.9","Cell RNA - U-2197 [nTPM]":"9.0","Cell RNA - U-251 MG [nTPM]":"4.5","Cell RNA - U-266\/70 [nTPM]":"1443.4","Cell RNA - U-266\/84 [nTPM]":"170.7","Cell RNA - U-698 [nTPM]":"1978.6","Cell RNA - U-87 MG [nTPM]":"745.9","Cell RNA - U-937 [nTPM]":"154.2","Cell RNA - WM-115 [nTPM]":"678.6","Blood RNA - basophil [nTPM]":"410.8","Blood RNA - classical monocyte [nTPM]":"11041.2","Blood RNA - eosinophil [nTPM]":"3996.9","Blood RNA - gdT-cell [nTPM]":"808.7","Blood RNA - intermediate monocyte [nTPM]":"15961.1","Blood RNA - MAIT T-cell [nTPM]":"899.9","Blood RNA - memory B-cell [nTPM]":"26889.3","Blood RNA - memory CD4 T-cell [nTPM]":"688.4","Blood RNA - memory CD8 T-cell [nTPM]":"1188.4","Blood RNA - myeloid DC [nTPM]":"23750.6","Blood RNA - naive B-cell [nTPM]":"27930.3","Blood RNA - naive CD4 T-cell [nTPM]":"378.9","Blood RNA - naive CD8 T-cell [nTPM]":"646.6","Blood RNA - neutrophil [nTPM]":"839.6","Blood RNA - NK-cell [nTPM]":"2378.1","Blood RNA - non-classical monocyte [nTPM]":"8003.3","Blood RNA - plasmacytoid DC [nTPM]":"16940.0","Blood RNA - T-reg [nTPM]":"2157.2","Blood RNA - total PBMC [nTPM]":"17779.7","Brain RNA - amygdala [nTPM]":"338.1","Brain RNA - basal ganglia [nTPM]":"301.9","Brain RNA - cerebellum [nTPM]":"365.5","Brain RNA - cerebral cortex [nTPM]":"474.4","Brain RNA - hippocampal formation [nTPM]":"306.7","Brain RNA - hypothalamus [nTPM]":"506.8","Brain RNA - medulla oblongata [nTPM]":"598.7","Brain RNA - midbrain [nTPM]":"431.8","Brain RNA - pons [nTPM]":"533.4","Brain RNA - spinal cord [nTPM]":"514.2","Brain RNA - thalamus [nTPM]":"514.4","Brain RNA - white matter [nTPM]":"771.8","Single Cell Type RNA - Adipocytes [nTPM]":"2080.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"419.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2160.4","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"10167.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"715.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"154.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"762.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"398.4","Single Cell Type RNA - Bipolar cells [nTPM]":"1.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"220.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"437.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"69.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"401.7","Single Cell Type RNA - Club cells [nTPM]":"1063.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"502.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"28.3","Single Cell Type RNA - dendritic cells [nTPM]":"3199.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"139.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"117.4","Single Cell Type RNA - Ductal cells [nTPM]":"1264.4","Single Cell Type RNA - Early spermatids [nTPM]":"10.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"111.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.5","Single Cell Type RNA - Endothelial cells [nTPM]":"1787.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"242.9","Single Cell Type RNA - Erythroid cells [nTPM]":"562.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"527.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"32.6","Single Cell Type RNA - Fibroblasts [nTPM]":"278.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"538.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"85.5","Single Cell Type RNA - granulocytes [nTPM]":"417.2","Single Cell Type RNA - Granulosa cells [nTPM]":"113.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"514.7","Single Cell Type RNA - Hepatocytes [nTPM]":"52.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"4361.8","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"475.7","Single Cell Type RNA - Ionocytes [nTPM]":"390.6","Single Cell Type RNA - Kupffer cells [nTPM]":"5201.6","Single Cell Type RNA - Langerhans cells [nTPM]":"23363.4","Single Cell Type RNA - Late spermatids [nTPM]":"31.3","Single Cell Type RNA - Leydig cells [nTPM]":"117.1","Single Cell Type RNA - Macrophages [nTPM]":"7290.2","Single Cell Type RNA - Melanocytes [nTPM]":"1197.1","Single Cell Type RNA - Microglial cells [nTPM]":"137.7","Single Cell Type RNA - monocytes [nTPM]":"10305.9","Single Cell Type RNA - Muller glia cells [nTPM]":"16.8","Single Cell Type RNA - NK-cells [nTPM]":"403.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"384.2","Single Cell Type RNA - Paneth cells [nTPM]":"487.3","Single Cell Type RNA - Peritubular cells [nTPM]":"17.7","Single Cell Type RNA - Plasma cells [nTPM]":"2068.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"174.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5034.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"815.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1153.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.0","Single Cell Type RNA - Sertoli cells [nTPM]":"164.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"45.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"146.7","Single Cell Type RNA - Spermatocytes [nTPM]":"2.8","Single Cell Type RNA - Spermatogonia [nTPM]":"12.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"170.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"575.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"41.6","Single Cell Type RNA - T-cells [nTPM]":"790.7","Single Cell Type RNA - Theca cells [nTPM]":"12.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"450.7","Single Cell Type RNA - Urothelial cells [nTPM]":"743.4"},{"Gene":"CD81","Gene synonym":["TAPA-1","TAPA1","TSPAN28"],"Ensembl":"ENSG00000110651","Gene description":"CD81 molecule","Uniprot":["P60033"],"Chromosome":"11","Position":"2376177-2397397","Protein class":["CD markers","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"1003.1","Endometrial stromal cells":"1050.9","Muller glia cells":"809.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"memory B-cell":"148.9","naive B-cell":"137.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"148.9"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"2960.6","fHDF\/TERT166":"1752.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002507","HPA007234"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"400000","Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB002507":"AB_563639","HPA007234":"AB_1846333"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.56e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.21e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.86e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Tissue RNA - adipose tissue [nTPM]":"892.1","Tissue RNA - adrenal gland [nTPM]":"299.1","Tissue RNA - amygdala [nTPM]":"560.6","Tissue RNA - appendix [nTPM]":"270.7","Tissue RNA - basal ganglia [nTPM]":"598.4","Tissue RNA - bone marrow [nTPM]":"77.8","Tissue RNA - breast [nTPM]":"773.6","Tissue RNA - cerebellum [nTPM]":"614.8","Tissue RNA - cerebral cortex [nTPM]":"590.2","Tissue RNA - cervix [nTPM]":"952.7","Tissue RNA - choroid plexus [nTPM]":"498.9","Tissue RNA - colon [nTPM]":"992.0","Tissue RNA - duodenum [nTPM]":"150.7","Tissue RNA - endometrium 1 [nTPM]":"1384.0","Tissue RNA - epididymis [nTPM]":"960.5","Tissue RNA - esophagus [nTPM]":"364.3","Tissue RNA - fallopian tube [nTPM]":"853.1","Tissue RNA - gallbladder [nTPM]":"534.5","Tissue RNA - heart muscle [nTPM]":"937.9","Tissue RNA - hippocampal formation [nTPM]":"511.1","Tissue RNA - hypothalamus [nTPM]":"615.8","Tissue RNA - kidney [nTPM]":"636.6","Tissue RNA - liver [nTPM]":"1175.7","Tissue RNA - lung [nTPM]":"768.4","Tissue RNA - lymph node [nTPM]":"429.0","Tissue RNA - medulla oblongata [nTPM]":"665.7","Tissue RNA - midbrain [nTPM]":"640.8","Tissue RNA - ovary [nTPM]":"656.8","Tissue RNA - pancreas [nTPM]":"449.5","Tissue RNA - parathyroid gland [nTPM]":"258.3","Tissue RNA - pituitary gland [nTPM]":"409.1","Tissue RNA - placenta [nTPM]":"441.0","Tissue RNA - pons [nTPM]":"651.1","Tissue RNA - prostate [nTPM]":"634.0","Tissue RNA - rectum [nTPM]":"234.4","Tissue RNA - retina [nTPM]":"75.9","Tissue RNA - salivary gland [nTPM]":"531.1","Tissue RNA - seminal vesicle [nTPM]":"1602.0","Tissue RNA - skeletal muscle [nTPM]":"214.3","Tissue RNA - skin 1 [nTPM]":"511.1","Tissue RNA - small intestine [nTPM]":"423.1","Tissue RNA - smooth muscle [nTPM]":"978.5","Tissue RNA - spinal cord [nTPM]":"694.1","Tissue RNA - spleen [nTPM]":"631.3","Tissue RNA - stomach 1 [nTPM]":"494.3","Tissue RNA - testis [nTPM]":"316.9","Tissue RNA - thalamus [nTPM]":"655.1","Tissue RNA - thymus [nTPM]":"158.9","Tissue RNA - thyroid gland [nTPM]":"564.6","Tissue RNA - tongue [nTPM]":"227.6","Tissue RNA - tonsil [nTPM]":"278.6","Tissue RNA - urinary bladder [nTPM]":"749.2","Tissue RNA - vagina [nTPM]":"763.4","Tissue RNA - white matter [nTPM]":"734.4","Cell RNA - A-431 [nTPM]":"337.0","Cell RNA - A549 [nTPM]":"342.0","Cell RNA - AF22 [nTPM]":"268.5","Cell RNA - AN3-CA [nTPM]":"413.4","Cell RNA - ASC diff [nTPM]":"2960.6","Cell RNA - ASC TERT1 [nTPM]":"1668.4","Cell RNA - BEWO [nTPM]":"224.8","Cell RNA - BJ [nTPM]":"621.0","Cell RNA - BJ hTERT+ [nTPM]":"1361.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"490.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"492.2","Cell RNA - CACO-2 [nTPM]":"322.8","Cell RNA - CAPAN-2 [nTPM]":"1.8","Cell RNA - Daudi [nTPM]":"285.4","Cell RNA - EFO-21 [nTPM]":"218.3","Cell RNA - fHDF\/TERT166 [nTPM]":"1752.6","Cell RNA - GAMG [nTPM]":"312.5","Cell RNA - HaCaT [nTPM]":"430.5","Cell RNA - HAP1 [nTPM]":"167.3","Cell RNA - HBEC3-KT [nTPM]":"442.2","Cell RNA - HBF TERT88 [nTPM]":"199.9","Cell RNA - HDLM-2 [nTPM]":"135.6","Cell RNA - HEK 293 [nTPM]":"517.8","Cell RNA - HEL [nTPM]":"43.7","Cell RNA - HeLa [nTPM]":"117.1","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"976.4","Cell RNA - HL-60 [nTPM]":"188.2","Cell RNA - HMC-1 [nTPM]":"359.8","Cell RNA - HSkMC [nTPM]":"1222.3","Cell RNA - hTCEpi [nTPM]":"619.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"201.1","Cell RNA - hTERT-HME1 [nTPM]":"302.1","Cell RNA - hTERT-RPE1 [nTPM]":"757.9","Cell RNA - HUVEC TERT2 [nTPM]":"476.6","Cell RNA - JURKAT [nTPM]":"204.0","Cell RNA - K-562 [nTPM]":"198.7","Cell RNA - Karpas-707 [nTPM]":"484.9","Cell RNA - LHCN-M2 [nTPM]":"696.4","Cell RNA - MCF7 [nTPM]":"257.2","Cell RNA - MOLT-4 [nTPM]":"160.7","Cell RNA - NB-4 [nTPM]":"239.1","Cell RNA - NTERA-2 [nTPM]":"324.4","Cell RNA - OE19 [nTPM]":"304.7","Cell RNA - PC-3 [nTPM]":"274.2","Cell RNA - REH [nTPM]":"324.7","Cell RNA - RH-30 [nTPM]":"135.5","Cell RNA - RPMI-8226 [nTPM]":"183.3","Cell RNA - RPTEC TERT1 [nTPM]":"529.1","Cell RNA - RT4 [nTPM]":"223.3","Cell RNA - SCLC-21H [nTPM]":"288.8","Cell RNA - SH-SY5Y [nTPM]":"319.2","Cell RNA - SiHa [nTPM]":"198.4","Cell RNA - SK-BR-3 [nTPM]":"514.4","Cell RNA - SK-MEL-30 [nTPM]":"383.8","Cell RNA - SuSa [nTPM]":"214.3","Cell RNA - T-47d [nTPM]":"171.0","Cell RNA - THP-1 [nTPM]":"337.8","Cell RNA - TIME [nTPM]":"641.3","Cell RNA - U-138 MG [nTPM]":"249.0","Cell RNA - U-2 OS [nTPM]":"181.6","Cell RNA - U-2197 [nTPM]":"471.2","Cell RNA - U-251 MG [nTPM]":"216.6","Cell RNA - U-266\/70 [nTPM]":"356.9","Cell RNA - U-266\/84 [nTPM]":"88.1","Cell RNA - U-698 [nTPM]":"529.1","Cell RNA - U-87 MG [nTPM]":"361.3","Cell RNA - U-937 [nTPM]":"111.0","Cell RNA - WM-115 [nTPM]":"435.0","Blood RNA - basophil [nTPM]":"0.9","Blood RNA - classical monocyte [nTPM]":"3.3","Blood RNA - eosinophil [nTPM]":"22.9","Blood RNA - gdT-cell [nTPM]":"21.1","Blood RNA - intermediate monocyte [nTPM]":"5.8","Blood RNA - MAIT T-cell [nTPM]":"34.4","Blood RNA - memory B-cell [nTPM]":"148.9","Blood RNA - memory CD4 T-cell [nTPM]":"14.9","Blood RNA - memory CD8 T-cell [nTPM]":"33.0","Blood RNA - myeloid DC [nTPM]":"2.6","Blood RNA - naive B-cell [nTPM]":"137.2","Blood RNA - naive CD4 T-cell [nTPM]":"9.2","Blood RNA - naive CD8 T-cell [nTPM]":"16.9","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"14.7","Blood RNA - non-classical monocyte [nTPM]":"7.3","Blood RNA - plasmacytoid DC [nTPM]":"7.7","Blood RNA - T-reg [nTPM]":"12.0","Blood RNA - total PBMC [nTPM]":"10.7","Brain RNA - amygdala [nTPM]":"560.6","Brain RNA - basal ganglia [nTPM]":"598.4","Brain RNA - cerebellum [nTPM]":"614.8","Brain RNA - cerebral cortex [nTPM]":"590.2","Brain RNA - hippocampal formation [nTPM]":"511.1","Brain RNA - hypothalamus [nTPM]":"615.8","Brain RNA - medulla oblongata [nTPM]":"665.7","Brain RNA - midbrain [nTPM]":"640.8","Brain RNA - pons [nTPM]":"651.1","Brain RNA - spinal cord [nTPM]":"694.1","Brain RNA - thalamus [nTPM]":"655.1","Brain RNA - white matter [nTPM]":"734.4","Single Cell Type RNA - Adipocytes [nTPM]":"1003.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"243.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"270.0","Single Cell Type RNA - Astrocytes [nTPM]":"95.0","Single Cell Type RNA - B-cells [nTPM]":"88.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"179.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"391.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"89.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.2","Single Cell Type RNA - Bipolar cells [nTPM]":"82.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"325.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"452.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"277.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"167.3","Single Cell Type RNA - Club cells [nTPM]":"102.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"207.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"21.8","Single Cell Type RNA - dendritic cells [nTPM]":"267.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"20.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"105.7","Single Cell Type RNA - Early spermatids [nTPM]":"15.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"365.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1050.9","Single Cell Type RNA - Endothelial cells [nTPM]":"344.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"71.9","Single Cell Type RNA - Erythroid cells [nTPM]":"30.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"55.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"31.7","Single Cell Type RNA - Fibroblasts [nTPM]":"560.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"462.7","Single Cell Type RNA - granulocytes [nTPM]":"81.7","Single Cell Type RNA - Granulosa cells [nTPM]":"204.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"293.4","Single Cell Type RNA - Hepatocytes [nTPM]":"603.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"251.5","Single Cell Type RNA - Horizontal cells [nTPM]":"148.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"32.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"48.2","Single Cell Type RNA - Ionocytes [nTPM]":"50.8","Single Cell Type RNA - Kupffer cells [nTPM]":"232.7","Single Cell Type RNA - Langerhans cells [nTPM]":"179.7","Single Cell Type RNA - Late spermatids [nTPM]":"50.2","Single Cell Type RNA - Leydig cells [nTPM]":"389.2","Single Cell Type RNA - Macrophages [nTPM]":"277.6","Single Cell Type RNA - Melanocytes [nTPM]":"151.2","Single Cell Type RNA - Microglial cells [nTPM]":"60.0","Single Cell Type RNA - monocytes [nTPM]":"23.0","Single Cell Type RNA - Muller glia cells [nTPM]":"809.2","Single Cell Type RNA - NK-cells [nTPM]":"45.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"145.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"93.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"61.3","Single Cell Type RNA - Paneth cells [nTPM]":"14.7","Single Cell Type RNA - Peritubular cells [nTPM]":"251.3","Single Cell Type RNA - Plasma cells [nTPM]":"50.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"147.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"29.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"85.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"76.1","Single Cell Type RNA - Sertoli cells [nTPM]":"118.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"356.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"423.6","Single Cell Type RNA - Spermatocytes [nTPM]":"15.6","Single Cell Type RNA - Spermatogonia [nTPM]":"19.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"30.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"164.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.1","Single Cell Type RNA - T-cells [nTPM]":"136.8","Single Cell Type RNA - Theca cells [nTPM]":"379.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"41.5","Single Cell Type RNA - Urothelial cells [nTPM]":"298.1"},{"Gene":"CDC14A","Gene synonym":["cdc14","Cdc14A1","Cdc14A2","DFNB105","DFNB32"],"Ensembl":"ENSG00000079335","Gene description":"Cell division cycle 14A","Uniprot":["Q9UNH5"],"Chromosome":"1","Position":"100345001-100520277","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Hearing"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"28.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"145.9","Early spermatids":"171.5","Late spermatids":"191.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"K-562":"44.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023783"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies","Cytosol"],"Antibody RRID":{"HPA023783":"AB_1846352"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.27e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.6","Tissue RNA - adrenal gland [nTPM]":"1.5","Tissue RNA - amygdala [nTPM]":"3.9","Tissue RNA - appendix [nTPM]":"4.6","Tissue RNA - basal ganglia [nTPM]":"3.1","Tissue RNA - bone marrow [nTPM]":"15.5","Tissue RNA - breast [nTPM]":"11.3","Tissue RNA - cerebellum [nTPM]":"2.7","Tissue RNA - cerebral cortex [nTPM]":"4.2","Tissue RNA - cervix [nTPM]":"5.4","Tissue RNA - choroid plexus [nTPM]":"5.2","Tissue RNA - colon [nTPM]":"6.0","Tissue RNA - duodenum [nTPM]":"7.3","Tissue RNA - endometrium 1 [nTPM]":"5.3","Tissue RNA - epididymis [nTPM]":"2.7","Tissue RNA - esophagus [nTPM]":"2.2","Tissue RNA - fallopian tube [nTPM]":"13.0","Tissue RNA - gallbladder [nTPM]":"3.3","Tissue RNA - heart muscle [nTPM]":"2.3","Tissue RNA - hippocampal formation [nTPM]":"3.7","Tissue RNA - hypothalamus [nTPM]":"4.5","Tissue RNA - kidney [nTPM]":"6.3","Tissue RNA - liver [nTPM]":"1.8","Tissue RNA - lung [nTPM]":"5.9","Tissue RNA - lymph node [nTPM]":"7.2","Tissue RNA - medulla oblongata [nTPM]":"4.3","Tissue RNA - midbrain [nTPM]":"4.9","Tissue RNA - ovary [nTPM]":"4.6","Tissue RNA - pancreas [nTPM]":"2.0","Tissue RNA - parathyroid gland [nTPM]":"6.0","Tissue RNA - pituitary gland [nTPM]":"3.6","Tissue RNA - placenta [nTPM]":"5.1","Tissue RNA - pons [nTPM]":"3.3","Tissue RNA - prostate [nTPM]":"7.6","Tissue RNA - rectum [nTPM]":"6.0","Tissue RNA - retina [nTPM]":"5.5","Tissue RNA - salivary gland [nTPM]":"3.4","Tissue RNA - seminal vesicle [nTPM]":"3.0","Tissue RNA - skeletal muscle [nTPM]":"2.6","Tissue RNA - skin 1 [nTPM]":"3.8","Tissue RNA - small intestine [nTPM]":"10.7","Tissue RNA - smooth muscle [nTPM]":"4.7","Tissue RNA - spinal cord [nTPM]":"3.5","Tissue RNA - spleen [nTPM]":"6.7","Tissue RNA - stomach 1 [nTPM]":"5.8","Tissue RNA - testis [nTPM]":"28.2","Tissue RNA - thalamus [nTPM]":"3.6","Tissue RNA - thymus [nTPM]":"6.4","Tissue RNA - thyroid gland [nTPM]":"5.8","Tissue RNA - tongue [nTPM]":"2.8","Tissue RNA - tonsil [nTPM]":"4.4","Tissue RNA - urinary bladder [nTPM]":"4.4","Tissue RNA - vagina [nTPM]":"3.3","Tissue RNA - white matter [nTPM]":"3.2","Cell RNA - A-431 [nTPM]":"3.3","Cell RNA - A549 [nTPM]":"2.6","Cell RNA - AF22 [nTPM]":"8.1","Cell RNA - AN3-CA [nTPM]":"9.3","Cell RNA - ASC diff [nTPM]":"2.9","Cell RNA - ASC TERT1 [nTPM]":"2.1","Cell RNA - BEWO [nTPM]":"5.7","Cell RNA - BJ [nTPM]":"4.1","Cell RNA - BJ hTERT+ [nTPM]":"2.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.1","Cell RNA - CACO-2 [nTPM]":"8.9","Cell RNA - CAPAN-2 [nTPM]":"2.7","Cell RNA - Daudi [nTPM]":"1.6","Cell RNA - EFO-21 [nTPM]":"3.0","Cell RNA - fHDF\/TERT166 [nTPM]":"2.4","Cell RNA - GAMG [nTPM]":"3.2","Cell RNA - HaCaT [nTPM]":"2.5","Cell RNA - HAP1 [nTPM]":"5.6","Cell RNA - HBEC3-KT [nTPM]":"2.3","Cell RNA - HBF TERT88 [nTPM]":"4.0","Cell RNA - HDLM-2 [nTPM]":"3.4","Cell RNA - HEK 293 [nTPM]":"13.7","Cell RNA - HEL [nTPM]":"5.8","Cell RNA - HeLa [nTPM]":"2.3","Cell RNA - Hep G2 [nTPM]":"2.9","Cell RNA - HHSteC [nTPM]":"1.1","Cell RNA - HL-60 [nTPM]":"7.8","Cell RNA - HMC-1 [nTPM]":"9.8","Cell RNA - HSkMC [nTPM]":"1.8","Cell RNA - hTCEpi [nTPM]":"0.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.3","Cell RNA - hTERT-HME1 [nTPM]":"1.4","Cell RNA - hTERT-RPE1 [nTPM]":"2.0","Cell RNA - HUVEC TERT2 [nTPM]":"7.0","Cell RNA - JURKAT [nTPM]":"3.3","Cell RNA - K-562 [nTPM]":"44.7","Cell RNA - Karpas-707 [nTPM]":"4.8","Cell RNA - LHCN-M2 [nTPM]":"5.8","Cell RNA - MCF7 [nTPM]":"1.4","Cell RNA - MOLT-4 [nTPM]":"6.3","Cell RNA - NB-4 [nTPM]":"8.7","Cell RNA - NTERA-2 [nTPM]":"5.1","Cell RNA - OE19 [nTPM]":"2.1","Cell RNA - PC-3 [nTPM]":"3.3","Cell RNA - REH [nTPM]":"6.8","Cell RNA - RH-30 [nTPM]":"10.6","Cell RNA - RPMI-8226 [nTPM]":"1.7","Cell RNA - RPTEC TERT1 [nTPM]":"2.8","Cell RNA - RT4 [nTPM]":"7.2","Cell RNA - SCLC-21H [nTPM]":"1.5","Cell RNA - SH-SY5Y [nTPM]":"2.7","Cell RNA - SiHa [nTPM]":"4.3","Cell RNA - SK-BR-3 [nTPM]":"4.1","Cell RNA - SK-MEL-30 [nTPM]":"5.6","Cell RNA - SuSa [nTPM]":"3.9","Cell RNA - T-47d [nTPM]":"1.9","Cell RNA - THP-1 [nTPM]":"10.0","Cell RNA - TIME [nTPM]":"3.1","Cell RNA - U-138 MG [nTPM]":"2.2","Cell RNA - U-2 OS [nTPM]":"4.9","Cell RNA - U-2197 [nTPM]":"3.8","Cell RNA - U-251 MG [nTPM]":"2.5","Cell RNA - U-266\/70 [nTPM]":"2.4","Cell RNA - U-266\/84 [nTPM]":"0.9","Cell RNA - U-698 [nTPM]":"2.5","Cell RNA - U-87 MG [nTPM]":"2.7","Cell RNA - U-937 [nTPM]":"7.3","Cell RNA - WM-115 [nTPM]":"1.3","Blood RNA - basophil [nTPM]":"12.2","Blood RNA - classical monocyte [nTPM]":"3.6","Blood RNA - eosinophil [nTPM]":"9.0","Blood RNA - gdT-cell [nTPM]":"6.9","Blood RNA - intermediate monocyte [nTPM]":"3.3","Blood RNA - MAIT T-cell [nTPM]":"12.5","Blood RNA - memory B-cell [nTPM]":"4.5","Blood RNA - memory CD4 T-cell [nTPM]":"10.9","Blood RNA - memory CD8 T-cell [nTPM]":"8.2","Blood RNA - myeloid DC [nTPM]":"3.5","Blood RNA - naive B-cell [nTPM]":"2.9","Blood RNA - naive CD4 T-cell [nTPM]":"10.2","Blood RNA - naive CD8 T-cell [nTPM]":"5.5","Blood RNA - neutrophil [nTPM]":"5.4","Blood RNA - NK-cell [nTPM]":"4.4","Blood RNA - non-classical monocyte [nTPM]":"2.3","Blood RNA - plasmacytoid DC [nTPM]":"6.2","Blood RNA - T-reg [nTPM]":"6.0","Blood RNA - total PBMC [nTPM]":"4.1","Brain RNA - amygdala [nTPM]":"3.9","Brain RNA - basal ganglia [nTPM]":"3.1","Brain RNA - cerebellum [nTPM]":"2.7","Brain RNA - cerebral cortex [nTPM]":"4.2","Brain RNA - hippocampal formation [nTPM]":"3.7","Brain RNA - hypothalamus [nTPM]":"4.5","Brain RNA - medulla oblongata [nTPM]":"4.3","Brain RNA - midbrain [nTPM]":"4.9","Brain RNA - pons [nTPM]":"3.3","Brain RNA - spinal cord [nTPM]":"3.5","Brain RNA - thalamus [nTPM]":"3.6","Brain RNA - white matter [nTPM]":"3.2","Single Cell Type RNA - Adipocytes [nTPM]":"14.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.5","Single Cell Type RNA - Astrocytes [nTPM]":"145.9","Single Cell Type RNA - B-cells [nTPM]":"10.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"4.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.7","Single Cell Type RNA - dendritic cells [nTPM]":"23.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.0","Single Cell Type RNA - Early spermatids [nTPM]":"171.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"48.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.8","Single Cell Type RNA - Endothelial cells [nTPM]":"13.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.0","Single Cell Type RNA - Fibroblasts [nTPM]":"7.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"51.1","Single Cell Type RNA - granulocytes [nTPM]":"15.2","Single Cell Type RNA - Granulosa cells [nTPM]":"4.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.1","Single Cell Type RNA - Hepatocytes [nTPM]":"1.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"5.5","Single Cell Type RNA - Langerhans cells [nTPM]":"7.3","Single Cell Type RNA - Late spermatids [nTPM]":"191.7","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"11.1","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"51.5","Single Cell Type RNA - monocytes [nTPM]":"9.3","Single Cell Type RNA - Muller glia cells [nTPM]":"11.4","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"53.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.1","Single Cell Type RNA - Paneth cells [nTPM]":"11.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"13.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.0","Single Cell Type RNA - Spermatocytes [nTPM]":"2.3","Single Cell Type RNA - Spermatogonia [nTPM]":"3.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.2","Single Cell Type RNA - T-cells [nTPM]":"44.1","Single Cell Type RNA - Theca cells [nTPM]":"3.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.7","Single Cell Type RNA - Urothelial cells [nTPM]":"4.1"},{"Gene":"CDC42","Gene synonym":["CDC42Hs","G25K"],"Ensembl":"ENSG00000070831","Gene description":"Cell division cycle 42","Uniprot":["P60953"],"Chromosome":"1","Position":"22025511-22101360","Protein class":["Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004360","HPA069590"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Microtubules","Cytokinetic bridge"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2700000","Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Microtubules","Cytokinetic bridge"],"Subcellular additional location":null,"Antibody RRID":{"CAB004360":"AB_627233","HPA069590":"AB_2732138"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.45e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.28e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.72e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Tissue RNA - adipose tissue [nTPM]":"177.4","Tissue RNA - adrenal gland [nTPM]":"116.1","Tissue RNA - amygdala [nTPM]":"91.7","Tissue RNA - appendix [nTPM]":"160.2","Tissue RNA - basal ganglia [nTPM]":"96.5","Tissue RNA - bone marrow [nTPM]":"402.9","Tissue RNA - breast [nTPM]":"142.7","Tissue RNA - cerebellum [nTPM]":"100.1","Tissue RNA - cerebral cortex [nTPM]":"113.8","Tissue RNA - cervix [nTPM]":"128.6","Tissue RNA - choroid plexus [nTPM]":"98.4","Tissue RNA - colon [nTPM]":"198.2","Tissue RNA - duodenum [nTPM]":"142.3","Tissue RNA - endometrium 1 [nTPM]":"131.3","Tissue RNA - epididymis [nTPM]":"99.8","Tissue RNA - esophagus [nTPM]":"162.3","Tissue RNA - fallopian tube [nTPM]":"124.8","Tissue RNA - gallbladder [nTPM]":"131.7","Tissue RNA - heart muscle [nTPM]":"117.0","Tissue RNA - hippocampal formation [nTPM]":"95.2","Tissue RNA - hypothalamus [nTPM]":"108.8","Tissue RNA - kidney [nTPM]":"158.8","Tissue RNA - liver [nTPM]":"153.5","Tissue RNA - lung [nTPM]":"154.1","Tissue RNA - lymph node [nTPM]":"167.9","Tissue RNA - medulla oblongata [nTPM]":"115.5","Tissue RNA - midbrain [nTPM]":"103.7","Tissue RNA - ovary [nTPM]":"105.9","Tissue RNA - pancreas [nTPM]":"82.5","Tissue RNA - parathyroid gland [nTPM]":"128.4","Tissue RNA - pituitary gland [nTPM]":"59.6","Tissue RNA - placenta [nTPM]":"170.3","Tissue RNA - pons [nTPM]":"108.4","Tissue RNA - prostate [nTPM]":"108.3","Tissue RNA - rectum [nTPM]":"185.4","Tissue RNA - retina [nTPM]":"95.9","Tissue RNA - salivary gland [nTPM]":"103.8","Tissue RNA - seminal vesicle [nTPM]":"107.5","Tissue RNA - skeletal muscle [nTPM]":"119.9","Tissue RNA - skin 1 [nTPM]":"132.0","Tissue RNA - small intestine [nTPM]":"156.9","Tissue RNA - smooth muscle [nTPM]":"175.0","Tissue RNA - spinal cord [nTPM]":"107.4","Tissue RNA - spleen [nTPM]":"157.5","Tissue RNA - stomach 1 [nTPM]":"159.9","Tissue RNA - testis [nTPM]":"64.2","Tissue RNA - thalamus [nTPM]":"102.2","Tissue RNA - thymus [nTPM]":"157.7","Tissue RNA - thyroid gland [nTPM]":"110.6","Tissue RNA - tongue [nTPM]":"120.9","Tissue RNA - tonsil [nTPM]":"216.8","Tissue RNA - urinary bladder [nTPM]":"194.8","Tissue RNA - vagina [nTPM]":"114.9","Tissue RNA - white matter [nTPM]":"127.1","Cell RNA - A-431 [nTPM]":"341.9","Cell RNA - A549 [nTPM]":"146.4","Cell RNA - AF22 [nTPM]":"272.2","Cell RNA - AN3-CA [nTPM]":"222.0","Cell RNA - ASC diff [nTPM]":"295.0","Cell RNA - ASC TERT1 [nTPM]":"306.4","Cell RNA - BEWO [nTPM]":"274.2","Cell RNA - BJ [nTPM]":"347.3","Cell RNA - BJ hTERT+ [nTPM]":"318.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"365.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"336.2","Cell RNA - CACO-2 [nTPM]":"178.0","Cell RNA - CAPAN-2 [nTPM]":"374.5","Cell RNA - Daudi [nTPM]":"253.1","Cell RNA - EFO-21 [nTPM]":"272.8","Cell RNA - fHDF\/TERT166 [nTPM]":"416.7","Cell RNA - GAMG [nTPM]":"136.2","Cell RNA - HaCaT [nTPM]":"210.7","Cell RNA - HAP1 [nTPM]":"241.1","Cell RNA - HBEC3-KT [nTPM]":"369.3","Cell RNA - HBF TERT88 [nTPM]":"431.1","Cell RNA - HDLM-2 [nTPM]":"332.4","Cell RNA - HEK 293 [nTPM]":"180.1","Cell RNA - HEL [nTPM]":"438.1","Cell RNA - HeLa [nTPM]":"184.5","Cell RNA - Hep G2 [nTPM]":"225.4","Cell RNA - HHSteC [nTPM]":"259.1","Cell RNA - HL-60 [nTPM]":"388.5","Cell RNA - HMC-1 [nTPM]":"350.5","Cell RNA - HSkMC [nTPM]":"285.6","Cell RNA - hTCEpi [nTPM]":"396.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"341.0","Cell RNA - hTERT-HME1 [nTPM]":"195.2","Cell RNA - hTERT-RPE1 [nTPM]":"234.7","Cell RNA - HUVEC TERT2 [nTPM]":"535.6","Cell RNA - JURKAT [nTPM]":"157.8","Cell RNA - K-562 [nTPM]":"250.8","Cell RNA - Karpas-707 [nTPM]":"273.4","Cell RNA - LHCN-M2 [nTPM]":"430.2","Cell RNA - MCF7 [nTPM]":"135.6","Cell RNA - MOLT-4 [nTPM]":"242.9","Cell RNA - NB-4 [nTPM]":"307.5","Cell RNA - NTERA-2 [nTPM]":"170.2","Cell RNA - OE19 [nTPM]":"242.9","Cell RNA - PC-3 [nTPM]":"179.3","Cell RNA - REH [nTPM]":"199.6","Cell RNA - RH-30 [nTPM]":"297.6","Cell RNA - RPMI-8226 [nTPM]":"243.3","Cell RNA - RPTEC TERT1 [nTPM]":"316.2","Cell RNA - RT4 [nTPM]":"301.3","Cell RNA - SCLC-21H [nTPM]":"183.4","Cell RNA - SH-SY5Y [nTPM]":"175.8","Cell RNA - SiHa [nTPM]":"293.4","Cell RNA - SK-BR-3 [nTPM]":"228.7","Cell RNA - SK-MEL-30 [nTPM]":"263.4","Cell RNA - SuSa [nTPM]":"296.3","Cell RNA - T-47d [nTPM]":"242.3","Cell RNA - THP-1 [nTPM]":"219.1","Cell RNA - TIME [nTPM]":"466.3","Cell RNA - U-138 MG [nTPM]":"265.3","Cell RNA - U-2 OS [nTPM]":"265.2","Cell RNA - U-2197 [nTPM]":"349.3","Cell RNA - U-251 MG [nTPM]":"207.8","Cell RNA - U-266\/70 [nTPM]":"148.6","Cell RNA - U-266\/84 [nTPM]":"355.9","Cell RNA - U-698 [nTPM]":"305.8","Cell RNA - U-87 MG [nTPM]":"234.5","Cell RNA - U-937 [nTPM]":"419.3","Cell RNA - WM-115 [nTPM]":"277.6","Blood RNA - basophil [nTPM]":"244.3","Blood RNA - classical monocyte [nTPM]":"200.6","Blood RNA - eosinophil [nTPM]":"255.1","Blood RNA - gdT-cell [nTPM]":"142.4","Blood RNA - intermediate monocyte [nTPM]":"282.3","Blood RNA - MAIT T-cell [nTPM]":"144.3","Blood RNA - memory B-cell [nTPM]":"108.0","Blood RNA - memory CD4 T-cell [nTPM]":"152.0","Blood RNA - memory CD8 T-cell [nTPM]":"146.7","Blood RNA - myeloid DC [nTPM]":"162.3","Blood RNA - naive B-cell [nTPM]":"103.4","Blood RNA - naive CD4 T-cell [nTPM]":"109.5","Blood RNA - naive CD8 T-cell [nTPM]":"143.5","Blood RNA - neutrophil [nTPM]":"308.3","Blood RNA - NK-cell [nTPM]":"145.0","Blood RNA - non-classical monocyte [nTPM]":"352.2","Blood RNA - plasmacytoid DC [nTPM]":"107.2","Blood RNA - T-reg [nTPM]":"157.4","Blood RNA - total PBMC [nTPM]":"244.8","Brain RNA - amygdala [nTPM]":"91.7","Brain RNA - basal ganglia [nTPM]":"96.5","Brain RNA - cerebellum [nTPM]":"100.1","Brain RNA - cerebral cortex [nTPM]":"113.8","Brain RNA - hippocampal formation [nTPM]":"95.2","Brain RNA - hypothalamus [nTPM]":"108.8","Brain RNA - medulla oblongata [nTPM]":"115.5","Brain RNA - midbrain [nTPM]":"103.7","Brain RNA - pons [nTPM]":"108.4","Brain RNA - spinal cord [nTPM]":"107.4","Brain RNA - thalamus [nTPM]":"102.2","Brain RNA - white matter [nTPM]":"127.1","Single Cell Type RNA - Adipocytes [nTPM]":"502.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"51.8","Single Cell Type RNA - Astrocytes [nTPM]":"20.9","Single Cell Type RNA - B-cells [nTPM]":"301.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"450.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"385.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"266.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"136.1","Single Cell Type RNA - Bipolar cells [nTPM]":"119.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"281.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"179.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"86.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"231.6","Single Cell Type RNA - Club cells [nTPM]":"168.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"312.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"349.6","Single Cell Type RNA - dendritic cells [nTPM]":"470.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"434.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"375.6","Single Cell Type RNA - Ductal cells [nTPM]":"441.3","Single Cell Type RNA - Early spermatids [nTPM]":"38.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"350.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"356.5","Single Cell Type RNA - Endothelial cells [nTPM]":"307.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"300.4","Single Cell Type RNA - Erythroid cells [nTPM]":"243.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"58.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"441.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"499.6","Single Cell Type RNA - Fibroblasts [nTPM]":"225.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"152.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"425.8","Single Cell Type RNA - granulocytes [nTPM]":"163.6","Single Cell Type RNA - Granulosa cells [nTPM]":"138.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"277.0","Single Cell Type RNA - Hepatocytes [nTPM]":"230.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"439.2","Single Cell Type RNA - Horizontal cells [nTPM]":"106.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"71.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"315.4","Single Cell Type RNA - Ionocytes [nTPM]":"187.2","Single Cell Type RNA - Kupffer cells [nTPM]":"585.4","Single Cell Type RNA - Langerhans cells [nTPM]":"875.2","Single Cell Type RNA - Late spermatids [nTPM]":"41.3","Single Cell Type RNA - Leydig cells [nTPM]":"157.8","Single Cell Type RNA - Macrophages [nTPM]":"443.4","Single Cell Type RNA - Melanocytes [nTPM]":"423.4","Single Cell Type RNA - Microglial cells [nTPM]":"53.4","Single Cell Type RNA - monocytes [nTPM]":"654.9","Single Cell Type RNA - Muller glia cells [nTPM]":"102.5","Single Cell Type RNA - NK-cells [nTPM]":"286.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"41.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"72.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"570.5","Single Cell Type RNA - Paneth cells [nTPM]":"369.7","Single Cell Type RNA - Peritubular cells [nTPM]":"177.1","Single Cell Type RNA - Plasma cells [nTPM]":"192.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"323.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"283.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"578.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"176.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"65.2","Single Cell Type RNA - Sertoli cells [nTPM]":"236.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"174.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"308.3","Single Cell Type RNA - Spermatocytes [nTPM]":"155.3","Single Cell Type RNA - Spermatogonia [nTPM]":"116.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"176.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"556.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"551.6","Single Cell Type RNA - T-cells [nTPM]":"379.2","Single Cell Type RNA - Theca cells [nTPM]":"178.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"286.7","Single Cell Type RNA - Urothelial cells [nTPM]":"469.6"},{"Gene":"CDK10","Gene synonym":["PISSLRE"],"Ensembl":"ENSG00000185324","Gene description":"Cyclin dependent kinase 10","Uniprot":["Q15131"],"Chromosome":"16","Position":"89680737-89696354","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007451","HPA059634","HPA067060"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Midbody","Midbody ring"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Midbody","Midbody ring"],"Antibody RRID":{"HPA007451":"AB_2732400","HPA059634":"AB_2684090","HPA067060":"AB_2685772"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.69e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.63e-4"},"Tissue RNA - adipose tissue [nTPM]":"30.1","Tissue RNA - adrenal gland [nTPM]":"38.5","Tissue RNA - amygdala [nTPM]":"20.2","Tissue RNA - appendix [nTPM]":"10.4","Tissue RNA - basal ganglia [nTPM]":"20.4","Tissue RNA - bone marrow [nTPM]":"19.5","Tissue RNA - breast [nTPM]":"26.7","Tissue RNA - cerebellum [nTPM]":"20.3","Tissue RNA - cerebral cortex [nTPM]":"32.8","Tissue RNA - cervix [nTPM]":"49.3","Tissue RNA - choroid plexus [nTPM]":"22.0","Tissue RNA - colon [nTPM]":"38.2","Tissue RNA - duodenum [nTPM]":"22.7","Tissue RNA - endometrium 1 [nTPM]":"25.9","Tissue RNA - epididymis [nTPM]":"8.7","Tissue RNA - esophagus [nTPM]":"35.3","Tissue RNA - fallopian tube [nTPM]":"36.3","Tissue RNA - gallbladder [nTPM]":"8.6","Tissue RNA - heart muscle [nTPM]":"27.3","Tissue RNA - hippocampal formation [nTPM]":"21.0","Tissue RNA - hypothalamus [nTPM]":"19.5","Tissue RNA - kidney [nTPM]":"52.9","Tissue RNA - liver [nTPM]":"77.0","Tissue RNA - lung [nTPM]":"31.0","Tissue RNA - lymph node [nTPM]":"14.7","Tissue RNA - medulla oblongata [nTPM]":"18.6","Tissue RNA - midbrain [nTPM]":"18.7","Tissue RNA - ovary [nTPM]":"43.2","Tissue RNA - pancreas [nTPM]":"49.2","Tissue RNA - parathyroid gland [nTPM]":"13.5","Tissue RNA - pituitary gland [nTPM]":"55.5","Tissue RNA - placenta [nTPM]":"12.5","Tissue RNA - pons [nTPM]":"19.6","Tissue RNA - prostate [nTPM]":"39.1","Tissue RNA - rectum [nTPM]":"11.3","Tissue RNA - retina [nTPM]":"7.6","Tissue RNA - salivary gland [nTPM]":"24.8","Tissue RNA - seminal vesicle [nTPM]":"7.5","Tissue RNA - skeletal muscle [nTPM]":"33.8","Tissue RNA - skin 1 [nTPM]":"32.1","Tissue RNA - small intestine [nTPM]":"36.1","Tissue RNA - smooth muscle [nTPM]":"8.2","Tissue RNA - spinal cord [nTPM]":"17.0","Tissue RNA - spleen [nTPM]":"37.5","Tissue RNA - stomach 1 [nTPM]":"38.5","Tissue RNA - testis [nTPM]":"17.0","Tissue RNA - thalamus [nTPM]":"18.4","Tissue RNA - thymus [nTPM]":"10.8","Tissue RNA - thyroid gland [nTPM]":"54.5","Tissue RNA - tongue [nTPM]":"4.1","Tissue RNA - tonsil [nTPM]":"7.0","Tissue RNA - urinary bladder [nTPM]":"32.3","Tissue RNA - vagina [nTPM]":"36.5","Tissue RNA - white matter [nTPM]":"19.1","Cell RNA - A-431 [nTPM]":"27.5","Cell RNA - A549 [nTPM]":"17.8","Cell RNA - AF22 [nTPM]":"13.9","Cell RNA - AN3-CA [nTPM]":"5.8","Cell RNA - ASC diff [nTPM]":"5.7","Cell RNA - ASC TERT1 [nTPM]":"11.0","Cell RNA - BEWO [nTPM]":"14.2","Cell RNA - BJ [nTPM]":"22.3","Cell RNA - BJ hTERT+ [nTPM]":"12.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.9","Cell RNA - CACO-2 [nTPM]":"13.1","Cell RNA - CAPAN-2 [nTPM]":"21.2","Cell RNA - Daudi [nTPM]":"23.9","Cell RNA - EFO-21 [nTPM]":"9.8","Cell RNA - fHDF\/TERT166 [nTPM]":"19.3","Cell RNA - GAMG [nTPM]":"9.1","Cell RNA - HaCaT [nTPM]":"15.5","Cell RNA - HAP1 [nTPM]":"5.8","Cell RNA - HBEC3-KT [nTPM]":"30.8","Cell RNA - HBF TERT88 [nTPM]":"9.3","Cell RNA - HDLM-2 [nTPM]":"5.3","Cell RNA - HEK 293 [nTPM]":"14.1","Cell RNA - HEL [nTPM]":"9.7","Cell RNA - HeLa [nTPM]":"21.0","Cell RNA - Hep G2 [nTPM]":"1.7","Cell RNA - HHSteC [nTPM]":"23.4","Cell RNA - HL-60 [nTPM]":"15.8","Cell RNA - HMC-1 [nTPM]":"17.1","Cell RNA - HSkMC [nTPM]":"13.3","Cell RNA - hTCEpi [nTPM]":"10.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.3","Cell RNA - hTERT-HME1 [nTPM]":"15.3","Cell RNA - hTERT-RPE1 [nTPM]":"10.3","Cell RNA - HUVEC TERT2 [nTPM]":"27.0","Cell RNA - JURKAT [nTPM]":"16.1","Cell RNA - K-562 [nTPM]":"25.5","Cell RNA - Karpas-707 [nTPM]":"3.2","Cell RNA - LHCN-M2 [nTPM]":"17.7","Cell RNA - MCF7 [nTPM]":"36.6","Cell RNA - MOLT-4 [nTPM]":"19.5","Cell RNA - NB-4 [nTPM]":"45.0","Cell RNA - NTERA-2 [nTPM]":"28.5","Cell RNA - OE19 [nTPM]":"29.7","Cell RNA - PC-3 [nTPM]":"13.1","Cell RNA - REH [nTPM]":"26.5","Cell RNA - RH-30 [nTPM]":"19.0","Cell RNA - RPMI-8226 [nTPM]":"34.1","Cell RNA - RPTEC TERT1 [nTPM]":"27.9","Cell RNA - RT4 [nTPM]":"21.2","Cell RNA - SCLC-21H [nTPM]":"10.1","Cell RNA - SH-SY5Y [nTPM]":"29.6","Cell RNA - SiHa [nTPM]":"28.0","Cell RNA - SK-BR-3 [nTPM]":"13.0","Cell RNA - SK-MEL-30 [nTPM]":"6.8","Cell RNA - SuSa [nTPM]":"15.2","Cell RNA - T-47d [nTPM]":"30.3","Cell RNA - THP-1 [nTPM]":"25.0","Cell RNA - TIME [nTPM]":"24.1","Cell RNA - U-138 MG [nTPM]":"9.1","Cell RNA - U-2 OS [nTPM]":"26.6","Cell RNA - U-2197 [nTPM]":"10.1","Cell RNA - U-251 MG [nTPM]":"15.4","Cell RNA - U-266\/70 [nTPM]":"11.7","Cell RNA - U-266\/84 [nTPM]":"6.4","Cell RNA - U-698 [nTPM]":"7.5","Cell RNA - U-87 MG [nTPM]":"16.4","Cell RNA - U-937 [nTPM]":"25.0","Cell RNA - WM-115 [nTPM]":"15.5","Blood RNA - basophil [nTPM]":"5.1","Blood RNA - classical monocyte [nTPM]":"14.0","Blood RNA - eosinophil [nTPM]":"4.2","Blood RNA - gdT-cell [nTPM]":"14.8","Blood RNA - intermediate monocyte [nTPM]":"19.7","Blood RNA - MAIT T-cell [nTPM]":"12.8","Blood RNA - memory B-cell [nTPM]":"7.8","Blood RNA - memory CD4 T-cell [nTPM]":"13.2","Blood RNA - memory CD8 T-cell [nTPM]":"10.7","Blood RNA - myeloid DC [nTPM]":"18.1","Blood RNA - naive B-cell [nTPM]":"9.0","Blood RNA - naive CD4 T-cell [nTPM]":"15.1","Blood RNA - naive CD8 T-cell [nTPM]":"12.6","Blood RNA - neutrophil [nTPM]":"1.5","Blood RNA - NK-cell [nTPM]":"20.4","Blood RNA - non-classical monocyte [nTPM]":"15.4","Blood RNA - plasmacytoid DC [nTPM]":"12.4","Blood RNA - T-reg [nTPM]":"11.6","Blood RNA - total PBMC [nTPM]":"11.4","Brain RNA - amygdala [nTPM]":"20.2","Brain RNA - basal ganglia [nTPM]":"20.4","Brain RNA - cerebellum [nTPM]":"20.3","Brain RNA - cerebral cortex [nTPM]":"32.8","Brain RNA - hippocampal formation [nTPM]":"21.0","Brain RNA - hypothalamus [nTPM]":"19.5","Brain RNA - medulla oblongata [nTPM]":"18.6","Brain RNA - midbrain [nTPM]":"18.7","Brain RNA - pons [nTPM]":"19.6","Brain RNA - spinal cord [nTPM]":"17.0","Brain RNA - thalamus [nTPM]":"18.4","Brain RNA - white matter [nTPM]":"19.1","Single Cell Type RNA - Adipocytes [nTPM]":"28.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.6","Single Cell Type RNA - Astrocytes [nTPM]":"35.3","Single Cell Type RNA - B-cells [nTPM]":"21.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"26.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.3","Single Cell Type RNA - Bipolar cells [nTPM]":"17.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"24.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"25.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"20.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"28.6","Single Cell Type RNA - dendritic cells [nTPM]":"26.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"43.0","Single Cell Type RNA - Ductal cells [nTPM]":"28.6","Single Cell Type RNA - Early spermatids [nTPM]":"6.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.9","Single Cell Type RNA - Endothelial cells [nTPM]":"23.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"67.7","Single Cell Type RNA - Erythroid cells [nTPM]":"15.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"44.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.8","Single Cell Type RNA - Fibroblasts [nTPM]":"19.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"85.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.9","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"40.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.8","Single Cell Type RNA - Hepatocytes [nTPM]":"41.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.8","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"33.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"49.4","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"17.4","Single Cell Type RNA - Langerhans cells [nTPM]":"16.0","Single Cell Type RNA - Late spermatids [nTPM]":"8.8","Single Cell Type RNA - Leydig cells [nTPM]":"23.9","Single Cell Type RNA - Macrophages [nTPM]":"17.0","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"15.5","Single Cell Type RNA - Muller glia cells [nTPM]":"8.5","Single Cell Type RNA - NK-cells [nTPM]":"26.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"24.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.6","Single Cell Type RNA - Paneth cells [nTPM]":"41.5","Single Cell Type RNA - Peritubular cells [nTPM]":"12.4","Single Cell Type RNA - Plasma cells [nTPM]":"20.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"58.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"53.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"32.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.3","Single Cell Type RNA - Spermatocytes [nTPM]":"27.3","Single Cell Type RNA - Spermatogonia [nTPM]":"28.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"27.9","Single Cell Type RNA - T-cells [nTPM]":"22.0","Single Cell Type RNA - Theca cells [nTPM]":"54.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"58.2","Single Cell Type RNA - Urothelial cells [nTPM]":"22.9"},{"Gene":"CDK12","Gene synonym":["CRK7","CRKR","CRKRS","KIAA0904"],"Ensembl":"ENSG00000167258","Gene description":"Cyclin dependent kinase 12","Uniprot":["Q9NYV4"],"Chromosome":"17","Position":"39461486-39564907","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SK-BR-3":"307.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008038","HPA073305"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nucleoplasm","Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA008038":"AB_1078570","HPA073305":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.5","Tissue RNA - adrenal gland [nTPM]":"7.6","Tissue RNA - amygdala [nTPM]":"2.5","Tissue RNA - appendix [nTPM]":"14.0","Tissue RNA - basal ganglia [nTPM]":"1.9","Tissue RNA - bone marrow [nTPM]":"34.3","Tissue RNA - breast [nTPM]":"9.5","Tissue RNA - cerebellum [nTPM]":"8.0","Tissue RNA - cerebral cortex [nTPM]":"4.0","Tissue RNA - cervix [nTPM]":"11.0","Tissue RNA - choroid plexus [nTPM]":"4.1","Tissue RNA - colon [nTPM]":"9.8","Tissue RNA - duodenum [nTPM]":"9.9","Tissue RNA - endometrium 1 [nTPM]":"10.8","Tissue RNA - epididymis [nTPM]":"6.0","Tissue RNA - esophagus [nTPM]":"10.4","Tissue RNA - fallopian tube [nTPM]":"9.2","Tissue RNA - gallbladder [nTPM]":"9.2","Tissue RNA - heart muscle [nTPM]":"6.8","Tissue RNA - hippocampal formation [nTPM]":"1.6","Tissue RNA - hypothalamus [nTPM]":"2.9","Tissue RNA - kidney [nTPM]":"8.0","Tissue RNA - liver [nTPM]":"12.3","Tissue RNA - lung [nTPM]":"9.2","Tissue RNA - lymph node [nTPM]":"15.1","Tissue RNA - medulla oblongata [nTPM]":"3.0","Tissue RNA - midbrain [nTPM]":"1.7","Tissue RNA - ovary [nTPM]":"11.9","Tissue RNA - pancreas [nTPM]":"8.7","Tissue RNA - parathyroid gland [nTPM]":"13.0","Tissue RNA - pituitary gland [nTPM]":"6.2","Tissue RNA - placenta [nTPM]":"11.5","Tissue RNA - pons [nTPM]":"1.6","Tissue RNA - prostate [nTPM]":"9.8","Tissue RNA - rectum [nTPM]":"10.4","Tissue RNA - retina [nTPM]":"11.7","Tissue RNA - salivary gland [nTPM]":"9.2","Tissue RNA - seminal vesicle [nTPM]":"9.3","Tissue RNA - skeletal muscle [nTPM]":"6.7","Tissue RNA - skin 1 [nTPM]":"10.6","Tissue RNA - small intestine [nTPM]":"10.4","Tissue RNA - smooth muscle [nTPM]":"10.0","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"12.9","Tissue RNA - stomach 1 [nTPM]":"10.3","Tissue RNA - testis [nTPM]":"17.7","Tissue RNA - thalamus [nTPM]":"3.4","Tissue RNA - thymus [nTPM]":"17.9","Tissue RNA - thyroid gland [nTPM]":"12.2","Tissue RNA - tongue [nTPM]":"7.8","Tissue RNA - tonsil [nTPM]":"15.3","Tissue RNA - urinary bladder [nTPM]":"13.1","Tissue RNA - vagina [nTPM]":"9.1","Tissue RNA - white matter [nTPM]":"3.3","Cell RNA - A-431 [nTPM]":"31.9","Cell RNA - A549 [nTPM]":"40.0","Cell RNA - AF22 [nTPM]":"24.9","Cell RNA - AN3-CA [nTPM]":"22.2","Cell RNA - ASC diff [nTPM]":"17.2","Cell RNA - ASC TERT1 [nTPM]":"19.0","Cell RNA - BEWO [nTPM]":"21.1","Cell RNA - BJ [nTPM]":"28.9","Cell RNA - BJ hTERT+ [nTPM]":"24.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"39.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"29.0","Cell RNA - CACO-2 [nTPM]":"48.1","Cell RNA - CAPAN-2 [nTPM]":"19.8","Cell RNA - Daudi [nTPM]":"45.4","Cell RNA - EFO-21 [nTPM]":"24.6","Cell RNA - fHDF\/TERT166 [nTPM]":"31.1","Cell RNA - GAMG [nTPM]":"38.7","Cell RNA - HaCaT [nTPM]":"51.8","Cell RNA - HAP1 [nTPM]":"49.2","Cell RNA - HBEC3-KT [nTPM]":"36.6","Cell RNA - HBF TERT88 [nTPM]":"38.4","Cell RNA - HDLM-2 [nTPM]":"29.6","Cell RNA - HEK 293 [nTPM]":"38.7","Cell RNA - HEL [nTPM]":"49.7","Cell RNA - HeLa [nTPM]":"26.9","Cell RNA - Hep G2 [nTPM]":"36.3","Cell RNA - HHSteC [nTPM]":"16.4","Cell RNA - HL-60 [nTPM]":"66.9","Cell RNA - HMC-1 [nTPM]":"33.4","Cell RNA - HSkMC [nTPM]":"20.4","Cell RNA - hTCEpi [nTPM]":"25.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"48.2","Cell RNA - hTERT-HME1 [nTPM]":"37.6","Cell RNA - hTERT-RPE1 [nTPM]":"16.0","Cell RNA - HUVEC TERT2 [nTPM]":"24.4","Cell RNA - JURKAT [nTPM]":"27.7","Cell RNA - K-562 [nTPM]":"85.2","Cell RNA - Karpas-707 [nTPM]":"30.7","Cell RNA - LHCN-M2 [nTPM]":"22.9","Cell RNA - MCF7 [nTPM]":"14.3","Cell RNA - MOLT-4 [nTPM]":"57.9","Cell RNA - NB-4 [nTPM]":"17.7","Cell RNA - NTERA-2 [nTPM]":"23.8","Cell RNA - OE19 [nTPM]":"16.0","Cell RNA - PC-3 [nTPM]":"16.9","Cell RNA - REH [nTPM]":"36.8","Cell RNA - RH-30 [nTPM]":"50.3","Cell RNA - RPMI-8226 [nTPM]":"25.7","Cell RNA - RPTEC TERT1 [nTPM]":"14.8","Cell RNA - RT4 [nTPM]":"38.8","Cell RNA - SCLC-21H [nTPM]":"24.6","Cell RNA - SH-SY5Y [nTPM]":"15.7","Cell RNA - SiHa [nTPM]":"37.0","Cell RNA - SK-BR-3 [nTPM]":"307.8","Cell RNA - SK-MEL-30 [nTPM]":"25.1","Cell RNA - SuSa [nTPM]":"34.8","Cell RNA - T-47d [nTPM]":"38.5","Cell RNA - THP-1 [nTPM]":"29.3","Cell RNA - TIME [nTPM]":"26.4","Cell RNA - U-138 MG [nTPM]":"34.5","Cell RNA - U-2 OS [nTPM]":"27.6","Cell RNA - U-2197 [nTPM]":"24.5","Cell RNA - U-251 MG [nTPM]":"37.9","Cell RNA - U-266\/70 [nTPM]":"23.6","Cell RNA - U-266\/84 [nTPM]":"18.4","Cell RNA - U-698 [nTPM]":"63.5","Cell RNA - U-87 MG [nTPM]":"24.2","Cell RNA - U-937 [nTPM]":"28.2","Cell RNA - WM-115 [nTPM]":"23.0","Blood RNA - basophil [nTPM]":"11.2","Blood RNA - classical monocyte [nTPM]":"2.0","Blood RNA - eosinophil [nTPM]":"3.2","Blood RNA - gdT-cell [nTPM]":"2.6","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"1.8","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"1.2","Blood RNA - naive B-cell [nTPM]":"3.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.6","Blood RNA - neutrophil [nTPM]":"7.0","Blood RNA - NK-cell [nTPM]":"4.5","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"2.7","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"2.5","Brain RNA - basal ganglia [nTPM]":"1.9","Brain RNA - cerebellum [nTPM]":"8.0","Brain RNA - cerebral cortex [nTPM]":"4.0","Brain RNA - hippocampal formation [nTPM]":"1.6","Brain RNA - hypothalamus [nTPM]":"2.9","Brain RNA - medulla oblongata [nTPM]":"3.0","Brain RNA - midbrain [nTPM]":"1.7","Brain RNA - pons [nTPM]":"1.6","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"3.4","Brain RNA - white matter [nTPM]":"3.3","Single Cell Type RNA - Adipocytes [nTPM]":"41.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.1","Single Cell Type RNA - Astrocytes [nTPM]":"50.9","Single Cell Type RNA - B-cells [nTPM]":"59.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"64.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"58.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"31.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"50.1","Single Cell Type RNA - Bipolar cells [nTPM]":"46.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"38.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"26.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"40.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"64.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"33.2","Single Cell Type RNA - dendritic cells [nTPM]":"59.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"30.2","Single Cell Type RNA - Early spermatids [nTPM]":"25.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"49.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"63.4","Single Cell Type RNA - Endothelial cells [nTPM]":"40.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"31.1","Single Cell Type RNA - Erythroid cells [nTPM]":"39.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"53.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"27.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"29.9","Single Cell Type RNA - Fibroblasts [nTPM]":"39.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"45.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"63.1","Single Cell Type RNA - granulocytes [nTPM]":"29.1","Single Cell Type RNA - Granulosa cells [nTPM]":"43.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.2","Single Cell Type RNA - Hepatocytes [nTPM]":"46.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"27.4","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"52.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"39.6","Single Cell Type RNA - Ionocytes [nTPM]":"42.7","Single Cell Type RNA - Kupffer cells [nTPM]":"45.9","Single Cell Type RNA - Langerhans cells [nTPM]":"49.1","Single Cell Type RNA - Late spermatids [nTPM]":"17.3","Single Cell Type RNA - Leydig cells [nTPM]":"37.3","Single Cell Type RNA - Macrophages [nTPM]":"41.3","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"32.8","Single Cell Type RNA - monocytes [nTPM]":"41.4","Single Cell Type RNA - Muller glia cells [nTPM]":"27.8","Single Cell Type RNA - NK-cells [nTPM]":"48.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"47.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"53.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"47.9","Single Cell Type RNA - Paneth cells [nTPM]":"33.9","Single Cell Type RNA - Peritubular cells [nTPM]":"33.8","Single Cell Type RNA - Plasma cells [nTPM]":"53.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"81.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"33.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"38.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"65.4","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"48.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"48.5","Single Cell Type RNA - Spermatocytes [nTPM]":"140.2","Single Cell Type RNA - Spermatogonia [nTPM]":"104.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"53.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"69.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"58.3","Single Cell Type RNA - T-cells [nTPM]":"59.0","Single Cell Type RNA - Theca cells [nTPM]":"46.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"39.9","Single Cell Type RNA - Urothelial cells [nTPM]":"84.8"},{"Gene":"CDK13","Gene synonym":["CDC2L","CDC2L5","CHED","KIAA1791"],"Ensembl":"ENSG00000065883","Gene description":"Cyclin dependent kinase 13","Uniprot":["Q14004"],"Chromosome":"7","Position":"39950121-40099580","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Host-virus interaction","mRNA processing","mRNA splicing"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"179.0","Oligodendrocyte precursor cells":"171.9","Oligodendrocytes":"199.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059241"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":["Golgi apparatus","Cytosol"],"Antibody RRID":{"HPA059241":"AB_2683956"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.4","Tissue RNA - adrenal gland [nTPM]":"10.2","Tissue RNA - amygdala [nTPM]":"8.8","Tissue RNA - appendix [nTPM]":"14.6","Tissue RNA - basal ganglia [nTPM]":"10.8","Tissue RNA - bone marrow [nTPM]":"28.1","Tissue RNA - breast [nTPM]":"11.1","Tissue RNA - cerebellum [nTPM]":"19.3","Tissue RNA - cerebral cortex [nTPM]":"9.9","Tissue RNA - cervix [nTPM]":"12.8","Tissue RNA - choroid plexus [nTPM]":"6.7","Tissue RNA - colon [nTPM]":"11.9","Tissue RNA - duodenum [nTPM]":"10.5","Tissue RNA - endometrium 1 [nTPM]":"13.6","Tissue RNA - epididymis [nTPM]":"14.2","Tissue RNA - esophagus [nTPM]":"14.7","Tissue RNA - fallopian tube [nTPM]":"15.0","Tissue RNA - gallbladder [nTPM]":"12.7","Tissue RNA - heart muscle [nTPM]":"10.4","Tissue RNA - hippocampal formation [nTPM]":"8.1","Tissue RNA - hypothalamus [nTPM]":"10.7","Tissue RNA - kidney [nTPM]":"12.7","Tissue RNA - liver [nTPM]":"15.9","Tissue RNA - lung [nTPM]":"12.1","Tissue RNA - lymph node [nTPM]":"21.7","Tissue RNA - medulla oblongata [nTPM]":"10.5","Tissue RNA - midbrain [nTPM]":"8.5","Tissue RNA - ovary [nTPM]":"20.1","Tissue RNA - pancreas [nTPM]":"12.8","Tissue RNA - parathyroid gland [nTPM]":"17.2","Tissue RNA - pituitary gland [nTPM]":"8.0","Tissue RNA - placenta [nTPM]":"13.6","Tissue RNA - pons [nTPM]":"8.6","Tissue RNA - prostate [nTPM]":"11.2","Tissue RNA - rectum [nTPM]":"13.6","Tissue RNA - retina [nTPM]":"19.7","Tissue RNA - salivary gland [nTPM]":"12.9","Tissue RNA - seminal vesicle [nTPM]":"11.8","Tissue RNA - skeletal muscle [nTPM]":"11.2","Tissue RNA - skin 1 [nTPM]":"12.0","Tissue RNA - small intestine [nTPM]":"12.0","Tissue RNA - smooth muscle [nTPM]":"12.0","Tissue RNA - spinal cord [nTPM]":"7.2","Tissue RNA - spleen [nTPM]":"16.6","Tissue RNA - stomach 1 [nTPM]":"12.3","Tissue RNA - testis [nTPM]":"19.0","Tissue RNA - thalamus [nTPM]":"10.1","Tissue RNA - thymus [nTPM]":"19.6","Tissue RNA - thyroid gland [nTPM]":"20.6","Tissue RNA - tongue [nTPM]":"14.0","Tissue RNA - tonsil [nTPM]":"20.2","Tissue RNA - urinary bladder [nTPM]":"13.4","Tissue RNA - vagina [nTPM]":"10.0","Tissue RNA - white matter [nTPM]":"14.9","Cell RNA - A-431 [nTPM]":"28.4","Cell RNA - A549 [nTPM]":"16.6","Cell RNA - AF22 [nTPM]":"28.2","Cell RNA - AN3-CA [nTPM]":"27.0","Cell RNA - ASC diff [nTPM]":"24.9","Cell RNA - ASC TERT1 [nTPM]":"24.1","Cell RNA - BEWO [nTPM]":"19.3","Cell RNA - BJ [nTPM]":"22.1","Cell RNA - BJ hTERT+ [nTPM]":"23.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.6","Cell RNA - CACO-2 [nTPM]":"17.8","Cell RNA - CAPAN-2 [nTPM]":"19.1","Cell RNA - Daudi [nTPM]":"51.0","Cell RNA - EFO-21 [nTPM]":"12.6","Cell RNA - fHDF\/TERT166 [nTPM]":"23.4","Cell RNA - GAMG [nTPM]":"34.8","Cell RNA - HaCaT [nTPM]":"33.6","Cell RNA - HAP1 [nTPM]":"23.4","Cell RNA - HBEC3-KT [nTPM]":"19.4","Cell RNA - HBF TERT88 [nTPM]":"29.0","Cell RNA - HDLM-2 [nTPM]":"25.3","Cell RNA - HEK 293 [nTPM]":"17.3","Cell RNA - HEL [nTPM]":"22.8","Cell RNA - HeLa [nTPM]":"20.0","Cell RNA - Hep G2 [nTPM]":"16.0","Cell RNA - HHSteC [nTPM]":"23.7","Cell RNA - HL-60 [nTPM]":"34.8","Cell RNA - HMC-1 [nTPM]":"23.5","Cell RNA - HSkMC [nTPM]":"14.3","Cell RNA - hTCEpi [nTPM]":"25.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.6","Cell RNA - hTERT-HME1 [nTPM]":"30.0","Cell RNA - hTERT-RPE1 [nTPM]":"22.6","Cell RNA - HUVEC TERT2 [nTPM]":"23.6","Cell RNA - JURKAT [nTPM]":"23.1","Cell RNA - K-562 [nTPM]":"39.0","Cell RNA - Karpas-707 [nTPM]":"34.3","Cell RNA - LHCN-M2 [nTPM]":"20.7","Cell RNA - MCF7 [nTPM]":"14.7","Cell RNA - MOLT-4 [nTPM]":"28.0","Cell RNA - NB-4 [nTPM]":"24.9","Cell RNA - NTERA-2 [nTPM]":"40.8","Cell RNA - OE19 [nTPM]":"20.0","Cell RNA - PC-3 [nTPM]":"19.1","Cell RNA - REH [nTPM]":"30.5","Cell RNA - RH-30 [nTPM]":"18.5","Cell RNA - RPMI-8226 [nTPM]":"20.5","Cell RNA - RPTEC TERT1 [nTPM]":"18.5","Cell RNA - RT4 [nTPM]":"28.1","Cell RNA - SCLC-21H [nTPM]":"20.0","Cell RNA - SH-SY5Y [nTPM]":"28.8","Cell RNA - SiHa [nTPM]":"27.6","Cell RNA - SK-BR-3 [nTPM]":"59.8","Cell RNA - SK-MEL-30 [nTPM]":"19.9","Cell RNA - SuSa [nTPM]":"36.7","Cell RNA - T-47d [nTPM]":"24.6","Cell RNA - THP-1 [nTPM]":"43.0","Cell RNA - TIME [nTPM]":"28.3","Cell RNA - U-138 MG [nTPM]":"27.0","Cell RNA - U-2 OS [nTPM]":"26.0","Cell RNA - U-2197 [nTPM]":"17.6","Cell RNA - U-251 MG [nTPM]":"30.5","Cell RNA - U-266\/70 [nTPM]":"28.3","Cell RNA - U-266\/84 [nTPM]":"26.0","Cell RNA - U-698 [nTPM]":"41.2","Cell RNA - U-87 MG [nTPM]":"19.8","Cell RNA - U-937 [nTPM]":"30.9","Cell RNA - WM-115 [nTPM]":"35.4","Blood RNA - basophil [nTPM]":"7.8","Blood RNA - classical monocyte [nTPM]":"2.2","Blood RNA - eosinophil [nTPM]":"4.0","Blood RNA - gdT-cell [nTPM]":"4.1","Blood RNA - intermediate monocyte [nTPM]":"1.9","Blood RNA - MAIT T-cell [nTPM]":"2.8","Blood RNA - memory B-cell [nTPM]":"6.4","Blood RNA - memory CD4 T-cell [nTPM]":"3.8","Blood RNA - memory CD8 T-cell [nTPM]":"3.0","Blood RNA - myeloid DC [nTPM]":"1.3","Blood RNA - naive B-cell [nTPM]":"10.5","Blood RNA - naive CD4 T-cell [nTPM]":"3.8","Blood RNA - naive CD8 T-cell [nTPM]":"3.9","Blood RNA - neutrophil [nTPM]":"5.9","Blood RNA - NK-cell [nTPM]":"4.3","Blood RNA - non-classical monocyte [nTPM]":"3.1","Blood RNA - plasmacytoid DC [nTPM]":"3.3","Blood RNA - T-reg [nTPM]":"3.9","Blood RNA - total PBMC [nTPM]":"1.3","Brain RNA - amygdala [nTPM]":"8.8","Brain RNA - basal ganglia [nTPM]":"10.8","Brain RNA - cerebellum [nTPM]":"19.3","Brain RNA - cerebral cortex [nTPM]":"9.9","Brain RNA - hippocampal formation [nTPM]":"8.1","Brain RNA - hypothalamus [nTPM]":"10.7","Brain RNA - medulla oblongata [nTPM]":"10.5","Brain RNA - midbrain [nTPM]":"8.5","Brain RNA - pons [nTPM]":"8.6","Brain RNA - spinal cord [nTPM]":"7.2","Brain RNA - thalamus [nTPM]":"10.1","Brain RNA - white matter [nTPM]":"14.9","Single Cell Type RNA - Adipocytes [nTPM]":"47.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"72.0","Single Cell Type RNA - Astrocytes [nTPM]":"131.6","Single Cell Type RNA - B-cells [nTPM]":"49.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"21.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"29.0","Single Cell Type RNA - Bipolar cells [nTPM]":"47.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"36.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"27.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"30.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"37.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"70.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.7","Single Cell Type RNA - dendritic cells [nTPM]":"91.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"20.4","Single Cell Type RNA - Early spermatids [nTPM]":"13.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"54.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"51.4","Single Cell Type RNA - Endothelial cells [nTPM]":"30.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.7","Single Cell Type RNA - Erythroid cells [nTPM]":"5.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"179.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.1","Single Cell Type RNA - Fibroblasts [nTPM]":"31.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"30.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"72.6","Single Cell Type RNA - granulocytes [nTPM]":"17.1","Single Cell Type RNA - Granulosa cells [nTPM]":"95.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.2","Single Cell Type RNA - Hepatocytes [nTPM]":"23.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.2","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"166.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.6","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"23.8","Single Cell Type RNA - Langerhans cells [nTPM]":"17.4","Single Cell Type RNA - Late spermatids [nTPM]":"9.2","Single Cell Type RNA - Leydig cells [nTPM]":"26.1","Single Cell Type RNA - Macrophages [nTPM]":"31.6","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"145.2","Single Cell Type RNA - monocytes [nTPM]":"27.9","Single Cell Type RNA - Muller glia cells [nTPM]":"22.4","Single Cell Type RNA - NK-cells [nTPM]":"53.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"171.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"199.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"28.6","Single Cell Type RNA - Paneth cells [nTPM]":"12.9","Single Cell Type RNA - Peritubular cells [nTPM]":"17.7","Single Cell Type RNA - Plasma cells [nTPM]":"50.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"21.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"32.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"69.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"38.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.0","Single Cell Type RNA - Spermatocytes [nTPM]":"36.1","Single Cell Type RNA - Spermatogonia [nTPM]":"33.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"34.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"26.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.2","Single Cell Type RNA - T-cells [nTPM]":"49.7","Single Cell Type RNA - Theca cells [nTPM]":"56.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.1","Single Cell Type RNA - Urothelial cells [nTPM]":"25.0"},{"Gene":"CDK5","Gene synonym":["PSSALRE"],"Ensembl":"ENSG00000164885","Gene description":"Cyclin dependent kinase 5","Uniprot":["Q00535"],"Chromosome":"7","Position":"151053815-151057897","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Biological rhythms","Cell cycle","Cell division","Neurogenesis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Lissencephaly","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"65.8"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB008909","HPA064535"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"CAB008909":null,"HPA064535":"AB_2685280"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.25e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.3","Tissue RNA - adrenal gland [nTPM]":"16.8","Tissue RNA - amygdala [nTPM]":"50.2","Tissue RNA - appendix [nTPM]":"9.4","Tissue RNA - basal ganglia [nTPM]":"53.2","Tissue RNA - bone marrow [nTPM]":"11.2","Tissue RNA - breast [nTPM]":"8.6","Tissue RNA - cerebellum [nTPM]":"44.9","Tissue RNA - cerebral cortex [nTPM]":"65.8","Tissue RNA - cervix [nTPM]":"8.6","Tissue RNA - choroid plexus [nTPM]":"40.0","Tissue RNA - colon [nTPM]":"9.3","Tissue RNA - duodenum [nTPM]":"10.9","Tissue RNA - endometrium 1 [nTPM]":"6.7","Tissue RNA - epididymis [nTPM]":"24.9","Tissue RNA - esophagus [nTPM]":"10.2","Tissue RNA - fallopian tube [nTPM]":"8.2","Tissue RNA - gallbladder [nTPM]":"9.5","Tissue RNA - heart muscle [nTPM]":"9.8","Tissue RNA - hippocampal formation [nTPM]":"57.5","Tissue RNA - hypothalamus [nTPM]":"50.9","Tissue RNA - kidney [nTPM]":"13.5","Tissue RNA - liver [nTPM]":"12.5","Tissue RNA - lung [nTPM]":"8.3","Tissue RNA - lymph node [nTPM]":"9.8","Tissue RNA - medulla oblongata [nTPM]":"48.6","Tissue RNA - midbrain [nTPM]":"45.3","Tissue RNA - ovary [nTPM]":"4.5","Tissue RNA - pancreas [nTPM]":"9.5","Tissue RNA - parathyroid gland [nTPM]":"22.8","Tissue RNA - pituitary gland [nTPM]":"14.7","Tissue RNA - placenta [nTPM]":"8.6","Tissue RNA - pons [nTPM]":"48.4","Tissue RNA - prostate [nTPM]":"8.8","Tissue RNA - rectum [nTPM]":"9.9","Tissue RNA - retina [nTPM]":"11.3","Tissue RNA - salivary gland [nTPM]":"9.6","Tissue RNA - seminal vesicle [nTPM]":"10.2","Tissue RNA - skeletal muscle [nTPM]":"8.5","Tissue RNA - skin 1 [nTPM]":"9.5","Tissue RNA - small intestine [nTPM]":"8.6","Tissue RNA - smooth muscle [nTPM]":"10.4","Tissue RNA - spinal cord [nTPM]":"43.2","Tissue RNA - spleen [nTPM]":"9.4","Tissue RNA - stomach 1 [nTPM]":"7.9","Tissue RNA - testis [nTPM]":"4.9","Tissue RNA - thalamus [nTPM]":"50.1","Tissue RNA - thymus [nTPM]":"14.2","Tissue RNA - thyroid gland [nTPM]":"10.0","Tissue RNA - tongue [nTPM]":"7.2","Tissue RNA - tonsil [nTPM]":"11.6","Tissue RNA - urinary bladder [nTPM]":"8.8","Tissue RNA - vagina [nTPM]":"6.0","Tissue RNA - white matter [nTPM]":"50.9","Cell RNA - A-431 [nTPM]":"31.9","Cell RNA - A549 [nTPM]":"40.8","Cell RNA - AF22 [nTPM]":"37.3","Cell RNA - AN3-CA [nTPM]":"59.7","Cell RNA - ASC diff [nTPM]":"48.8","Cell RNA - ASC TERT1 [nTPM]":"36.1","Cell RNA - BEWO [nTPM]":"17.8","Cell RNA - BJ [nTPM]":"24.4","Cell RNA - BJ hTERT+ [nTPM]":"41.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"47.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"40.3","Cell RNA - CACO-2 [nTPM]":"31.2","Cell RNA - CAPAN-2 [nTPM]":"31.0","Cell RNA - Daudi [nTPM]":"34.7","Cell RNA - EFO-21 [nTPM]":"71.3","Cell RNA - fHDF\/TERT166 [nTPM]":"31.8","Cell RNA - GAMG [nTPM]":"63.5","Cell RNA - HaCaT [nTPM]":"23.5","Cell RNA - HAP1 [nTPM]":"67.8","Cell RNA - HBEC3-KT [nTPM]":"40.6","Cell RNA - HBF TERT88 [nTPM]":"22.6","Cell RNA - HDLM-2 [nTPM]":"24.9","Cell RNA - HEK 293 [nTPM]":"43.3","Cell RNA - HEL [nTPM]":"38.2","Cell RNA - HeLa [nTPM]":"32.4","Cell RNA - Hep G2 [nTPM]":"30.7","Cell RNA - HHSteC [nTPM]":"31.6","Cell RNA - HL-60 [nTPM]":"29.0","Cell RNA - HMC-1 [nTPM]":"64.4","Cell RNA - HSkMC [nTPM]":"37.9","Cell RNA - hTCEpi [nTPM]":"28.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"39.0","Cell RNA - hTERT-HME1 [nTPM]":"13.5","Cell RNA - hTERT-RPE1 [nTPM]":"62.8","Cell RNA - HUVEC TERT2 [nTPM]":"38.8","Cell RNA - JURKAT [nTPM]":"57.6","Cell RNA - K-562 [nTPM]":"36.3","Cell RNA - Karpas-707 [nTPM]":"24.0","Cell RNA - LHCN-M2 [nTPM]":"50.7","Cell RNA - MCF7 [nTPM]":"68.4","Cell RNA - MOLT-4 [nTPM]":"76.4","Cell RNA - NB-4 [nTPM]":"57.9","Cell RNA - NTERA-2 [nTPM]":"39.3","Cell RNA - OE19 [nTPM]":"57.2","Cell RNA - PC-3 [nTPM]":"80.5","Cell RNA - REH [nTPM]":"38.9","Cell RNA - RH-30 [nTPM]":"14.8","Cell RNA - RPMI-8226 [nTPM]":"41.5","Cell RNA - RPTEC TERT1 [nTPM]":"46.2","Cell RNA - RT4 [nTPM]":"27.9","Cell RNA - SCLC-21H [nTPM]":"23.0","Cell RNA - SH-SY5Y [nTPM]":"97.8","Cell RNA - SiHa [nTPM]":"30.9","Cell RNA - SK-BR-3 [nTPM]":"37.7","Cell RNA - SK-MEL-30 [nTPM]":"43.8","Cell RNA - SuSa [nTPM]":"36.0","Cell RNA - T-47d [nTPM]":"18.6","Cell RNA - THP-1 [nTPM]":"25.9","Cell RNA - TIME [nTPM]":"22.7","Cell RNA - U-138 MG [nTPM]":"42.2","Cell RNA - U-2 OS [nTPM]":"10.3","Cell RNA - U-2197 [nTPM]":"31.2","Cell RNA - U-251 MG [nTPM]":"39.2","Cell RNA - U-266\/70 [nTPM]":"52.1","Cell RNA - U-266\/84 [nTPM]":"61.4","Cell RNA - U-698 [nTPM]":"13.7","Cell RNA - U-87 MG [nTPM]":"66.4","Cell RNA - U-937 [nTPM]":"46.5","Cell RNA - WM-115 [nTPM]":"75.8","Blood RNA - basophil [nTPM]":"18.9","Blood RNA - classical monocyte [nTPM]":"39.4","Blood RNA - eosinophil [nTPM]":"20.1","Blood RNA - gdT-cell [nTPM]":"13.5","Blood RNA - intermediate monocyte [nTPM]":"46.2","Blood RNA - MAIT T-cell [nTPM]":"11.1","Blood RNA - memory B-cell [nTPM]":"13.3","Blood RNA - memory CD4 T-cell [nTPM]":"12.8","Blood RNA - memory CD8 T-cell [nTPM]":"13.6","Blood RNA - myeloid DC [nTPM]":"44.7","Blood RNA - naive B-cell [nTPM]":"12.8","Blood RNA - naive CD4 T-cell [nTPM]":"9.8","Blood RNA - naive CD8 T-cell [nTPM]":"11.8","Blood RNA - neutrophil [nTPM]":"5.7","Blood RNA - NK-cell [nTPM]":"19.9","Blood RNA - non-classical monocyte [nTPM]":"36.4","Blood RNA - plasmacytoid DC [nTPM]":"26.9","Blood RNA - T-reg [nTPM]":"31.9","Blood RNA - total PBMC [nTPM]":"23.8","Brain RNA - amygdala [nTPM]":"50.2","Brain RNA - basal ganglia [nTPM]":"53.2","Brain RNA - cerebellum [nTPM]":"44.9","Brain RNA - cerebral cortex [nTPM]":"65.8","Brain RNA - hippocampal formation [nTPM]":"57.5","Brain RNA - hypothalamus [nTPM]":"50.9","Brain RNA - medulla oblongata [nTPM]":"48.6","Brain RNA - midbrain [nTPM]":"45.3","Brain RNA - pons [nTPM]":"48.4","Brain RNA - spinal cord [nTPM]":"43.2","Brain RNA - thalamus [nTPM]":"50.1","Brain RNA - white matter [nTPM]":"50.9","Single Cell Type RNA - Adipocytes [nTPM]":"7.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"6.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"12.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"14.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"26.8","Single Cell Type RNA - dendritic cells [nTPM]":"5.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"39.2","Single Cell Type RNA - Ductal cells [nTPM]":"21.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.9","Single Cell Type RNA - Endothelial cells [nTPM]":"8.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.0","Single Cell Type RNA - Erythroid cells [nTPM]":"12.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.3","Single Cell Type RNA - Fibroblasts [nTPM]":"7.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.3","Single Cell Type RNA - granulocytes [nTPM]":"30.5","Single Cell Type RNA - Granulosa cells [nTPM]":"23.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"11.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"41.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.9","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"21.9","Single Cell Type RNA - Langerhans cells [nTPM]":"6.2","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"4.7","Single Cell Type RNA - Macrophages [nTPM]":"16.6","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"19.9","Single Cell Type RNA - Muller glia cells [nTPM]":"12.6","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.8","Single Cell Type RNA - Paneth cells [nTPM]":"15.0","Single Cell Type RNA - Peritubular cells [nTPM]":"11.3","Single Cell Type RNA - Plasma cells [nTPM]":"12.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"35.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.1","Single Cell Type RNA - Spermatocytes [nTPM]":"3.9","Single Cell Type RNA - Spermatogonia [nTPM]":"11.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.0","Single Cell Type RNA - T-cells [nTPM]":"7.3","Single Cell Type RNA - Theca cells [nTPM]":"14.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.5","Single Cell Type RNA - Urothelial cells [nTPM]":"9.0"},{"Gene":"CDK8","Gene synonym":["K35"],"Ensembl":"ENSG00000132964","Gene description":"Cyclin dependent kinase 8","Uniprot":["P49336"],"Chromosome":"13","Position":"26254104-26405238","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","Kinase","Repressor","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Autism spectrum disorder","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"118.7","Inhibitory neurons":"175.4","Late spermatids":"100.4","Oligodendrocyte precursor cells":"149.3","Oligodendrocytes":"91.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044721"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA044721":"AB_2679059"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.23e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.37e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.4","Tissue RNA - adrenal gland [nTPM]":"2.9","Tissue RNA - amygdala [nTPM]":"2.2","Tissue RNA - appendix [nTPM]":"3.5","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"3.2","Tissue RNA - breast [nTPM]":"3.0","Tissue RNA - cerebellum [nTPM]":"7.6","Tissue RNA - cerebral cortex [nTPM]":"3.0","Tissue RNA - cervix [nTPM]":"2.9","Tissue RNA - choroid plexus [nTPM]":"1.2","Tissue RNA - colon [nTPM]":"10.5","Tissue RNA - duodenum [nTPM]":"7.7","Tissue RNA - endometrium 1 [nTPM]":"4.0","Tissue RNA - epididymis [nTPM]":"3.2","Tissue RNA - esophagus [nTPM]":"5.1","Tissue RNA - fallopian tube [nTPM]":"2.5","Tissue RNA - gallbladder [nTPM]":"3.9","Tissue RNA - heart muscle [nTPM]":"4.1","Tissue RNA - hippocampal formation [nTPM]":"3.0","Tissue RNA - hypothalamus [nTPM]":"2.7","Tissue RNA - kidney [nTPM]":"5.1","Tissue RNA - liver [nTPM]":"5.7","Tissue RNA - lung [nTPM]":"2.9","Tissue RNA - lymph node [nTPM]":"3.1","Tissue RNA - medulla oblongata [nTPM]":"2.7","Tissue RNA - midbrain [nTPM]":"3.0","Tissue RNA - ovary [nTPM]":"2.5","Tissue RNA - pancreas [nTPM]":"7.1","Tissue RNA - parathyroid gland [nTPM]":"5.1","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"5.9","Tissue RNA - pons [nTPM]":"2.4","Tissue RNA - prostate [nTPM]":"3.5","Tissue RNA - rectum [nTPM]":"6.0","Tissue RNA - retina [nTPM]":"8.5","Tissue RNA - salivary gland [nTPM]":"4.6","Tissue RNA - seminal vesicle [nTPM]":"6.9","Tissue RNA - skeletal muscle [nTPM]":"5.0","Tissue RNA - skin 1 [nTPM]":"3.1","Tissue RNA - small intestine [nTPM]":"7.5","Tissue RNA - smooth muscle [nTPM]":"6.6","Tissue RNA - spinal cord [nTPM]":"2.1","Tissue RNA - spleen [nTPM]":"2.5","Tissue RNA - stomach 1 [nTPM]":"5.0","Tissue RNA - testis [nTPM]":"9.7","Tissue RNA - thalamus [nTPM]":"2.6","Tissue RNA - thymus [nTPM]":"5.9","Tissue RNA - thyroid gland [nTPM]":"3.4","Tissue RNA - tongue [nTPM]":"5.2","Tissue RNA - tonsil [nTPM]":"4.1","Tissue RNA - urinary bladder [nTPM]":"6.2","Tissue RNA - vagina [nTPM]":"2.5","Tissue RNA - white matter [nTPM]":"2.1","Cell RNA - A-431 [nTPM]":"10.1","Cell RNA - A549 [nTPM]":"8.4","Cell RNA - AF22 [nTPM]":"16.5","Cell RNA - AN3-CA [nTPM]":"16.4","Cell RNA - ASC diff [nTPM]":"8.3","Cell RNA - ASC TERT1 [nTPM]":"10.2","Cell RNA - BEWO [nTPM]":"10.3","Cell RNA - BJ [nTPM]":"19.6","Cell RNA - BJ hTERT+ [nTPM]":"13.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.0","Cell RNA - CACO-2 [nTPM]":"23.8","Cell RNA - CAPAN-2 [nTPM]":"13.6","Cell RNA - Daudi [nTPM]":"10.7","Cell RNA - EFO-21 [nTPM]":"8.3","Cell RNA - fHDF\/TERT166 [nTPM]":"9.8","Cell RNA - GAMG [nTPM]":"11.6","Cell RNA - HaCaT [nTPM]":"12.2","Cell RNA - HAP1 [nTPM]":"18.7","Cell RNA - HBEC3-KT [nTPM]":"12.9","Cell RNA - HBF TERT88 [nTPM]":"17.2","Cell RNA - HDLM-2 [nTPM]":"25.8","Cell RNA - HEK 293 [nTPM]":"10.3","Cell RNA - HEL [nTPM]":"20.5","Cell RNA - HeLa [nTPM]":"6.4","Cell RNA - Hep G2 [nTPM]":"8.2","Cell RNA - HHSteC [nTPM]":"5.8","Cell RNA - HL-60 [nTPM]":"32.3","Cell RNA - HMC-1 [nTPM]":"11.4","Cell RNA - HSkMC [nTPM]":"7.5","Cell RNA - hTCEpi [nTPM]":"12.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.7","Cell RNA - hTERT-HME1 [nTPM]":"17.3","Cell RNA - hTERT-RPE1 [nTPM]":"7.8","Cell RNA - HUVEC TERT2 [nTPM]":"10.2","Cell RNA - JURKAT [nTPM]":"18.1","Cell RNA - K-562 [nTPM]":"32.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"12.5","Cell RNA - MCF7 [nTPM]":"10.7","Cell RNA - MOLT-4 [nTPM]":"25.2","Cell RNA - NB-4 [nTPM]":"15.1","Cell RNA - NTERA-2 [nTPM]":"13.2","Cell RNA - OE19 [nTPM]":"15.5","Cell RNA - PC-3 [nTPM]":"9.9","Cell RNA - REH [nTPM]":"15.4","Cell RNA - RH-30 [nTPM]":"15.9","Cell RNA - RPMI-8226 [nTPM]":"7.6","Cell RNA - RPTEC TERT1 [nTPM]":"8.2","Cell RNA - RT4 [nTPM]":"9.2","Cell RNA - SCLC-21H [nTPM]":"13.6","Cell RNA - SH-SY5Y [nTPM]":"8.6","Cell RNA - SiHa [nTPM]":"8.1","Cell RNA - SK-BR-3 [nTPM]":"15.1","Cell RNA - SK-MEL-30 [nTPM]":"13.9","Cell RNA - SuSa [nTPM]":"12.7","Cell RNA - T-47d [nTPM]":"5.5","Cell RNA - THP-1 [nTPM]":"14.6","Cell RNA - TIME [nTPM]":"10.5","Cell RNA - U-138 MG [nTPM]":"8.8","Cell RNA - U-2 OS [nTPM]":"11.3","Cell RNA - U-2197 [nTPM]":"16.1","Cell RNA - U-251 MG [nTPM]":"10.4","Cell RNA - U-266\/70 [nTPM]":"7.8","Cell RNA - U-266\/84 [nTPM]":"15.2","Cell RNA - U-698 [nTPM]":"19.3","Cell RNA - U-87 MG [nTPM]":"5.5","Cell RNA - U-937 [nTPM]":"13.2","Cell RNA - WM-115 [nTPM]":"10.7","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"1.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"2.2","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"7.6","Brain RNA - cerebral cortex [nTPM]":"3.0","Brain RNA - hippocampal formation [nTPM]":"3.0","Brain RNA - hypothalamus [nTPM]":"2.7","Brain RNA - medulla oblongata [nTPM]":"2.7","Brain RNA - midbrain [nTPM]":"3.0","Brain RNA - pons [nTPM]":"2.4","Brain RNA - spinal cord [nTPM]":"2.1","Brain RNA - thalamus [nTPM]":"2.6","Brain RNA - white matter [nTPM]":"2.1","Single Cell Type RNA - Adipocytes [nTPM]":"6.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.4","Single Cell Type RNA - Astrocytes [nTPM]":"63.6","Single Cell Type RNA - B-cells [nTPM]":"11.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"19.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"20.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"6.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.2","Single Cell Type RNA - dendritic cells [nTPM]":"9.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"8.9","Single Cell Type RNA - Early spermatids [nTPM]":"66.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.7","Single Cell Type RNA - Endothelial cells [nTPM]":"6.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"9.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"118.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.7","Single Cell Type RNA - Fibroblasts [nTPM]":"9.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"8.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"8.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.0","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"175.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.6","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"9.1","Single Cell Type RNA - Langerhans cells [nTPM]":"11.3","Single Cell Type RNA - Late spermatids [nTPM]":"100.4","Single Cell Type RNA - Leydig cells [nTPM]":"7.8","Single Cell Type RNA - Macrophages [nTPM]":"7.9","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"58.1","Single Cell Type RNA - monocytes [nTPM]":"8.4","Single Cell Type RNA - Muller glia cells [nTPM]":"7.7","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"149.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"91.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.5","Single Cell Type RNA - Paneth cells [nTPM]":"10.9","Single Cell Type RNA - Peritubular cells [nTPM]":"8.2","Single Cell Type RNA - Plasma cells [nTPM]":"14.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"67.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.9","Single Cell Type RNA - Spermatocytes [nTPM]":"32.9","Single Cell Type RNA - Spermatogonia [nTPM]":"18.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"23.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.7","Single Cell Type RNA - T-cells [nTPM]":"10.8","Single Cell Type RNA - Theca cells [nTPM]":"11.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.7","Single Cell Type RNA - Urothelial cells [nTPM]":"16.2"},{"Gene":"CDK9","Gene synonym":["C-2k","CDC2L4","PITALRE","TAK"],"Ensembl":"ENSG00000136807","Gene description":"Cyclin dependent kinase 9","Uniprot":["P50750"],"Chromosome":"9","Position":"127785679-127790792","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Transcription","Transcription regulation"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004216","HPA006738"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytoplasmic bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 65: Plasmacytoid DCs - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytoplasmic bodies"],"Antibody RRID":{"CAB004216":"AB_627245","HPA006738":"AB_1078493"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.92e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-3"},"Tissue RNA - adipose tissue [nTPM]":"44.6","Tissue RNA - adrenal gland [nTPM]":"60.8","Tissue RNA - amygdala [nTPM]":"44.3","Tissue RNA - appendix [nTPM]":"23.7","Tissue RNA - basal ganglia [nTPM]":"43.7","Tissue RNA - bone marrow [nTPM]":"47.0","Tissue RNA - breast [nTPM]":"40.3","Tissue RNA - cerebellum [nTPM]":"40.8","Tissue RNA - cerebral cortex [nTPM]":"53.8","Tissue RNA - cervix [nTPM]":"55.5","Tissue RNA - choroid plexus [nTPM]":"35.4","Tissue RNA - colon [nTPM]":"49.3","Tissue RNA - duodenum [nTPM]":"19.7","Tissue RNA - endometrium 1 [nTPM]":"49.3","Tissue RNA - epididymis [nTPM]":"21.1","Tissue RNA - esophagus [nTPM]":"35.4","Tissue RNA - fallopian tube [nTPM]":"65.6","Tissue RNA - gallbladder [nTPM]":"23.7","Tissue RNA - heart muscle [nTPM]":"40.4","Tissue RNA - hippocampal formation [nTPM]":"50.8","Tissue RNA - hypothalamus [nTPM]":"42.0","Tissue RNA - kidney [nTPM]":"44.5","Tissue RNA - liver [nTPM]":"65.1","Tissue RNA - lung [nTPM]":"47.2","Tissue RNA - lymph node [nTPM]":"35.1","Tissue RNA - medulla oblongata [nTPM]":"44.7","Tissue RNA - midbrain [nTPM]":"44.1","Tissue RNA - ovary [nTPM]":"88.5","Tissue RNA - pancreas [nTPM]":"44.4","Tissue RNA - parathyroid gland [nTPM]":"19.2","Tissue RNA - pituitary gland [nTPM]":"67.0","Tissue RNA - placenta [nTPM]":"18.7","Tissue RNA - pons [nTPM]":"41.1","Tissue RNA - prostate [nTPM]":"44.1","Tissue RNA - rectum [nTPM]":"12.2","Tissue RNA - retina [nTPM]":"11.1","Tissue RNA - salivary gland [nTPM]":"29.7","Tissue RNA - seminal vesicle [nTPM]":"23.3","Tissue RNA - skeletal muscle [nTPM]":"28.3","Tissue RNA - skin 1 [nTPM]":"38.7","Tissue RNA - small intestine [nTPM]":"40.9","Tissue RNA - smooth muscle [nTPM]":"19.1","Tissue RNA - spinal cord [nTPM]":"42.7","Tissue RNA - spleen [nTPM]":"65.6","Tissue RNA - stomach 1 [nTPM]":"37.4","Tissue RNA - testis [nTPM]":"44.3","Tissue RNA - thalamus [nTPM]":"42.1","Tissue RNA - thymus [nTPM]":"31.9","Tissue RNA - thyroid gland [nTPM]":"42.1","Tissue RNA - tongue [nTPM]":"17.1","Tissue RNA - tonsil [nTPM]":"20.9","Tissue RNA - urinary bladder [nTPM]":"38.9","Tissue RNA - vagina [nTPM]":"40.5","Tissue RNA - white matter [nTPM]":"44.4","Cell RNA - A-431 [nTPM]":"22.5","Cell RNA - A549 [nTPM]":"40.5","Cell RNA - AF22 [nTPM]":"24.9","Cell RNA - AN3-CA [nTPM]":"27.6","Cell RNA - ASC diff [nTPM]":"27.6","Cell RNA - ASC TERT1 [nTPM]":"21.4","Cell RNA - BEWO [nTPM]":"32.1","Cell RNA - BJ [nTPM]":"22.9","Cell RNA - BJ hTERT+ [nTPM]":"33.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.9","Cell RNA - CACO-2 [nTPM]":"30.3","Cell RNA - CAPAN-2 [nTPM]":"25.0","Cell RNA - Daudi [nTPM]":"39.5","Cell RNA - EFO-21 [nTPM]":"25.7","Cell RNA - fHDF\/TERT166 [nTPM]":"26.0","Cell RNA - GAMG [nTPM]":"32.1","Cell RNA - HaCaT [nTPM]":"44.2","Cell RNA - HAP1 [nTPM]":"16.5","Cell RNA - HBEC3-KT [nTPM]":"37.3","Cell RNA - HBF TERT88 [nTPM]":"8.9","Cell RNA - HDLM-2 [nTPM]":"34.8","Cell RNA - HEK 293 [nTPM]":"19.0","Cell RNA - HEL [nTPM]":"37.1","Cell RNA - HeLa [nTPM]":"45.2","Cell RNA - Hep G2 [nTPM]":"25.3","Cell RNA - HHSteC [nTPM]":"40.2","Cell RNA - HL-60 [nTPM]":"36.3","Cell RNA - HMC-1 [nTPM]":"56.5","Cell RNA - HSkMC [nTPM]":"37.9","Cell RNA - hTCEpi [nTPM]":"44.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"24.8","Cell RNA - hTERT-HME1 [nTPM]":"27.7","Cell RNA - hTERT-RPE1 [nTPM]":"30.0","Cell RNA - HUVEC TERT2 [nTPM]":"48.5","Cell RNA - JURKAT [nTPM]":"34.8","Cell RNA - K-562 [nTPM]":"32.6","Cell RNA - Karpas-707 [nTPM]":"51.7","Cell RNA - LHCN-M2 [nTPM]":"21.2","Cell RNA - MCF7 [nTPM]":"60.1","Cell RNA - MOLT-4 [nTPM]":"39.5","Cell RNA - NB-4 [nTPM]":"54.5","Cell RNA - NTERA-2 [nTPM]":"55.0","Cell RNA - OE19 [nTPM]":"34.3","Cell RNA - PC-3 [nTPM]":"41.9","Cell RNA - REH [nTPM]":"112.2","Cell RNA - RH-30 [nTPM]":"21.2","Cell RNA - RPMI-8226 [nTPM]":"57.0","Cell RNA - RPTEC TERT1 [nTPM]":"34.2","Cell RNA - RT4 [nTPM]":"24.9","Cell RNA - SCLC-21H [nTPM]":"24.5","Cell RNA - SH-SY5Y [nTPM]":"29.2","Cell RNA - SiHa [nTPM]":"34.5","Cell RNA - SK-BR-3 [nTPM]":"35.8","Cell RNA - SK-MEL-30 [nTPM]":"20.9","Cell RNA - SuSa [nTPM]":"19.3","Cell RNA - T-47d [nTPM]":"45.0","Cell RNA - THP-1 [nTPM]":"33.9","Cell RNA - TIME [nTPM]":"56.4","Cell RNA - U-138 MG [nTPM]":"27.8","Cell RNA - U-2 OS [nTPM]":"30.9","Cell RNA - U-2197 [nTPM]":"24.1","Cell RNA - U-251 MG [nTPM]":"22.3","Cell RNA - U-266\/70 [nTPM]":"92.5","Cell RNA - U-266\/84 [nTPM]":"76.4","Cell RNA - U-698 [nTPM]":"34.7","Cell RNA - U-87 MG [nTPM]":"26.1","Cell RNA - U-937 [nTPM]":"24.4","Cell RNA - WM-115 [nTPM]":"25.9","Blood RNA - basophil [nTPM]":"4.1","Blood RNA - classical monocyte [nTPM]":"3.7","Blood RNA - eosinophil [nTPM]":"5.8","Blood RNA - gdT-cell [nTPM]":"10.3","Blood RNA - intermediate monocyte [nTPM]":"5.1","Blood RNA - MAIT T-cell [nTPM]":"10.1","Blood RNA - memory B-cell [nTPM]":"3.6","Blood RNA - memory CD4 T-cell [nTPM]":"5.7","Blood RNA - memory CD8 T-cell [nTPM]":"8.3","Blood RNA - myeloid DC [nTPM]":"4.8","Blood RNA - naive B-cell [nTPM]":"6.6","Blood RNA - naive CD4 T-cell [nTPM]":"6.3","Blood RNA - naive CD8 T-cell [nTPM]":"7.9","Blood RNA - neutrophil [nTPM]":"5.4","Blood RNA - NK-cell [nTPM]":"22.4","Blood RNA - non-classical monocyte [nTPM]":"7.5","Blood RNA - plasmacytoid DC [nTPM]":"9.9","Blood RNA - T-reg [nTPM]":"4.4","Blood RNA - total PBMC [nTPM]":"3.6","Brain RNA - amygdala [nTPM]":"44.3","Brain RNA - basal ganglia [nTPM]":"43.7","Brain RNA - cerebellum [nTPM]":"40.8","Brain RNA - cerebral cortex [nTPM]":"53.8","Brain RNA - hippocampal formation [nTPM]":"50.8","Brain RNA - hypothalamus [nTPM]":"42.0","Brain RNA - medulla oblongata [nTPM]":"44.7","Brain RNA - midbrain [nTPM]":"44.1","Brain RNA - pons [nTPM]":"41.1","Brain RNA - spinal cord [nTPM]":"42.7","Brain RNA - thalamus [nTPM]":"42.1","Brain RNA - white matter [nTPM]":"44.4","Single Cell Type RNA - Adipocytes [nTPM]":"43.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.4","Single Cell Type RNA - Astrocytes [nTPM]":"39.8","Single Cell Type RNA - B-cells [nTPM]":"27.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"24.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Bipolar cells [nTPM]":"13.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"10.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"22.5","Single Cell Type RNA - dendritic cells [nTPM]":"28.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"31.3","Single Cell Type RNA - Early spermatids [nTPM]":"4.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"26.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.7","Single Cell Type RNA - Endothelial cells [nTPM]":"35.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.2","Single Cell Type RNA - Erythroid cells [nTPM]":"15.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"37.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"22.3","Single Cell Type RNA - Fibroblasts [nTPM]":"23.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"24.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.3","Single Cell Type RNA - granulocytes [nTPM]":"25.3","Single Cell Type RNA - Granulosa cells [nTPM]":"18.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"33.5","Single Cell Type RNA - Hepatocytes [nTPM]":"26.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.3","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.7","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"18.8","Single Cell Type RNA - Langerhans cells [nTPM]":"23.4","Single Cell Type RNA - Late spermatids [nTPM]":"6.2","Single Cell Type RNA - Leydig cells [nTPM]":"19.6","Single Cell Type RNA - Macrophages [nTPM]":"24.2","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"22.5","Single Cell Type RNA - monocytes [nTPM]":"44.7","Single Cell Type RNA - Muller glia cells [nTPM]":"17.5","Single Cell Type RNA - NK-cells [nTPM]":"33.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"32.9","Single Cell Type RNA - Paneth cells [nTPM]":"13.7","Single Cell Type RNA - Peritubular cells [nTPM]":"31.2","Single Cell Type RNA - Plasma cells [nTPM]":"22.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"28.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.1","Single Cell Type RNA - Spermatocytes [nTPM]":"8.9","Single Cell Type RNA - Spermatogonia [nTPM]":"22.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"51.3","Single Cell Type RNA - T-cells [nTPM]":"24.7","Single Cell Type RNA - Theca cells [nTPM]":"54.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.7","Single Cell Type RNA - Urothelial cells [nTPM]":"31.4"},{"Gene":"CDKAL1","Gene synonym":["FLJ20342"],"Ensembl":"ENSG00000145996","Gene description":"CDK5 regulatory subunit associated protein 1 like 1","Uniprot":["Q5VV42"],"Chromosome":"6","Position":"20534457-21232404","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["tRNA processing"],"Molecular function":["Transferase"],"Disease involvement":["Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Astrocytes":"133.2","Excitatory neurons":"159.5","Inhibitory neurons":"134.1","Microglial cells":"198.6","Oligodendrocyte precursor cells":"198.5","Oligodendrocytes":"255.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"SCLC-21H":"188.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.03e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.6","Tissue RNA - adrenal gland [nTPM]":"4.0","Tissue RNA - amygdala [nTPM]":"3.6","Tissue RNA - appendix [nTPM]":"5.8","Tissue RNA - basal ganglia [nTPM]":"5.7","Tissue RNA - bone marrow [nTPM]":"9.5","Tissue RNA - breast [nTPM]":"6.9","Tissue RNA - cerebellum [nTPM]":"7.2","Tissue RNA - cerebral cortex [nTPM]":"4.3","Tissue RNA - cervix [nTPM]":"6.6","Tissue RNA - choroid plexus [nTPM]":"5.8","Tissue RNA - colon [nTPM]":"5.2","Tissue RNA - duodenum [nTPM]":"4.6","Tissue RNA - endometrium 1 [nTPM]":"8.1","Tissue RNA - epididymis [nTPM]":"5.8","Tissue RNA - esophagus [nTPM]":"4.9","Tissue RNA - fallopian tube [nTPM]":"6.8","Tissue RNA - gallbladder [nTPM]":"6.3","Tissue RNA - heart muscle [nTPM]":"4.7","Tissue RNA - hippocampal formation [nTPM]":"3.5","Tissue RNA - hypothalamus [nTPM]":"4.9","Tissue RNA - kidney [nTPM]":"5.6","Tissue RNA - liver [nTPM]":"5.4","Tissue RNA - lung [nTPM]":"5.5","Tissue RNA - lymph node [nTPM]":"8.2","Tissue RNA - medulla oblongata [nTPM]":"6.5","Tissue RNA - midbrain [nTPM]":"4.9","Tissue RNA - ovary [nTPM]":"8.5","Tissue RNA - pancreas [nTPM]":"5.7","Tissue RNA - parathyroid gland [nTPM]":"6.5","Tissue RNA - pituitary gland [nTPM]":"4.0","Tissue RNA - placenta [nTPM]":"6.6","Tissue RNA - pons [nTPM]":"6.5","Tissue RNA - prostate [nTPM]":"5.5","Tissue RNA - rectum [nTPM]":"6.5","Tissue RNA - retina [nTPM]":"5.3","Tissue RNA - salivary gland [nTPM]":"5.9","Tissue RNA - seminal vesicle [nTPM]":"4.9","Tissue RNA - skeletal muscle [nTPM]":"14.0","Tissue RNA - skin 1 [nTPM]":"7.4","Tissue RNA - small intestine [nTPM]":"5.1","Tissue RNA - smooth muscle [nTPM]":"6.4","Tissue RNA - spinal cord [nTPM]":"4.8","Tissue RNA - spleen [nTPM]":"7.2","Tissue RNA - stomach 1 [nTPM]":"5.8","Tissue RNA - testis [nTPM]":"6.7","Tissue RNA - thalamus [nTPM]":"4.9","Tissue RNA - thymus [nTPM]":"9.6","Tissue RNA - thyroid gland [nTPM]":"9.4","Tissue RNA - tongue [nTPM]":"9.5","Tissue RNA - tonsil [nTPM]":"8.6","Tissue RNA - urinary bladder [nTPM]":"5.7","Tissue RNA - vagina [nTPM]":"5.1","Tissue RNA - white matter [nTPM]":"9.0","Cell RNA - A-431 [nTPM]":"8.7","Cell RNA - A549 [nTPM]":"5.3","Cell RNA - AF22 [nTPM]":"12.1","Cell RNA - AN3-CA [nTPM]":"15.6","Cell RNA - ASC diff [nTPM]":"6.7","Cell RNA - ASC TERT1 [nTPM]":"9.0","Cell RNA - BEWO [nTPM]":"12.8","Cell RNA - BJ [nTPM]":"9.0","Cell RNA - BJ hTERT+ [nTPM]":"8.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.1","Cell RNA - CACO-2 [nTPM]":"9.8","Cell RNA - CAPAN-2 [nTPM]":"7.7","Cell RNA - Daudi [nTPM]":"20.7","Cell RNA - EFO-21 [nTPM]":"22.0","Cell RNA - fHDF\/TERT166 [nTPM]":"7.7","Cell RNA - GAMG [nTPM]":"14.1","Cell RNA - HaCaT [nTPM]":"8.6","Cell RNA - HAP1 [nTPM]":"16.5","Cell RNA - HBEC3-KT [nTPM]":"9.1","Cell RNA - HBF TERT88 [nTPM]":"17.3","Cell RNA - HDLM-2 [nTPM]":"37.3","Cell RNA - HEK 293 [nTPM]":"9.1","Cell RNA - HEL [nTPM]":"17.7","Cell RNA - HeLa [nTPM]":"9.1","Cell RNA - Hep G2 [nTPM]":"13.3","Cell RNA - HHSteC [nTPM]":"8.7","Cell RNA - HL-60 [nTPM]":"17.6","Cell RNA - HMC-1 [nTPM]":"11.7","Cell RNA - HSkMC [nTPM]":"8.2","Cell RNA - hTCEpi [nTPM]":"9.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.5","Cell RNA - hTERT-HME1 [nTPM]":"11.5","Cell RNA - hTERT-RPE1 [nTPM]":"8.0","Cell RNA - HUVEC TERT2 [nTPM]":"12.0","Cell RNA - JURKAT [nTPM]":"12.6","Cell RNA - K-562 [nTPM]":"23.3","Cell RNA - Karpas-707 [nTPM]":"8.2","Cell RNA - LHCN-M2 [nTPM]":"9.7","Cell RNA - MCF7 [nTPM]":"7.3","Cell RNA - MOLT-4 [nTPM]":"22.4","Cell RNA - NB-4 [nTPM]":"21.0","Cell RNA - NTERA-2 [nTPM]":"8.5","Cell RNA - OE19 [nTPM]":"8.9","Cell RNA - PC-3 [nTPM]":"5.8","Cell RNA - REH [nTPM]":"13.1","Cell RNA - RH-30 [nTPM]":"16.1","Cell RNA - RPMI-8226 [nTPM]":"19.5","Cell RNA - RPTEC TERT1 [nTPM]":"16.6","Cell RNA - RT4 [nTPM]":"9.9","Cell RNA - SCLC-21H [nTPM]":"188.5","Cell RNA - SH-SY5Y [nTPM]":"11.1","Cell RNA - SiHa [nTPM]":"10.0","Cell RNA - SK-BR-3 [nTPM]":"16.0","Cell RNA - SK-MEL-30 [nTPM]":"13.2","Cell RNA - SuSa [nTPM]":"10.2","Cell RNA - T-47d [nTPM]":"11.7","Cell RNA - THP-1 [nTPM]":"8.8","Cell RNA - TIME [nTPM]":"11.7","Cell RNA - U-138 MG [nTPM]":"15.2","Cell RNA - U-2 OS [nTPM]":"10.4","Cell RNA - U-2197 [nTPM]":"6.1","Cell RNA - U-251 MG [nTPM]":"16.8","Cell RNA - U-266\/70 [nTPM]":"12.9","Cell RNA - U-266\/84 [nTPM]":"36.8","Cell RNA - U-698 [nTPM]":"17.7","Cell RNA - U-87 MG [nTPM]":"5.5","Cell RNA - U-937 [nTPM]":"9.9","Cell RNA - WM-115 [nTPM]":"26.0","Blood RNA - basophil [nTPM]":"1.5","Blood RNA - classical monocyte [nTPM]":"3.3","Blood RNA - eosinophil [nTPM]":"3.1","Blood RNA - gdT-cell [nTPM]":"6.4","Blood RNA - intermediate monocyte [nTPM]":"5.3","Blood RNA - MAIT T-cell [nTPM]":"5.3","Blood RNA - memory B-cell [nTPM]":"7.0","Blood RNA - memory CD4 T-cell [nTPM]":"6.3","Blood RNA - memory CD8 T-cell [nTPM]":"6.5","Blood RNA - myeloid DC [nTPM]":"4.4","Blood RNA - naive B-cell [nTPM]":"6.4","Blood RNA - naive CD4 T-cell [nTPM]":"7.7","Blood RNA - naive CD8 T-cell [nTPM]":"7.1","Blood RNA - neutrophil [nTPM]":"1.5","Blood RNA - NK-cell [nTPM]":"10.3","Blood RNA - non-classical monocyte [nTPM]":"11.2","Blood RNA - plasmacytoid DC [nTPM]":"4.6","Blood RNA - T-reg [nTPM]":"7.4","Blood RNA - total PBMC [nTPM]":"3.5","Brain RNA - amygdala [nTPM]":"3.6","Brain RNA - basal ganglia [nTPM]":"5.7","Brain RNA - cerebellum [nTPM]":"7.2","Brain RNA - cerebral cortex [nTPM]":"4.3","Brain RNA - hippocampal formation [nTPM]":"3.5","Brain RNA - hypothalamus [nTPM]":"4.9","Brain RNA - medulla oblongata [nTPM]":"6.5","Brain RNA - midbrain [nTPM]":"4.9","Brain RNA - pons [nTPM]":"6.5","Brain RNA - spinal cord [nTPM]":"4.8","Brain RNA - thalamus [nTPM]":"4.9","Brain RNA - white matter [nTPM]":"9.0","Single Cell Type RNA - Adipocytes [nTPM]":"13.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.6","Single Cell Type RNA - Astrocytes [nTPM]":"133.2","Single Cell Type RNA - B-cells [nTPM]":"19.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"8.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"8.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.4","Single Cell Type RNA - dendritic cells [nTPM]":"12.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"8.3","Single Cell Type RNA - Early spermatids [nTPM]":"15.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.6","Single Cell Type RNA - Endothelial cells [nTPM]":"12.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"33.4","Single Cell Type RNA - Erythroid cells [nTPM]":"6.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"159.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.0","Single Cell Type RNA - Fibroblasts [nTPM]":"9.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.5","Single Cell Type RNA - granulocytes [nTPM]":"13.3","Single Cell Type RNA - Granulosa cells [nTPM]":"12.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.2","Single Cell Type RNA - Hepatocytes [nTPM]":"6.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.1","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"134.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.5","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"6.1","Single Cell Type RNA - Langerhans cells [nTPM]":"7.6","Single Cell Type RNA - Late spermatids [nTPM]":"6.3","Single Cell Type RNA - Leydig cells [nTPM]":"8.7","Single Cell Type RNA - Macrophages [nTPM]":"9.5","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"198.6","Single Cell Type RNA - monocytes [nTPM]":"13.2","Single Cell Type RNA - Muller glia cells [nTPM]":"6.0","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"198.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"255.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.8","Single Cell Type RNA - Paneth cells [nTPM]":"5.8","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"20.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.7","Single Cell Type RNA - Spermatocytes [nTPM]":"13.3","Single Cell Type RNA - Spermatogonia [nTPM]":"11.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.0","Single Cell Type RNA - T-cells [nTPM]":"17.4","Single Cell Type RNA - Theca cells [nTPM]":"5.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.1","Single Cell Type RNA - Urothelial cells [nTPM]":"6.3"},{"Gene":"CDKL5","Gene synonym":["CFAP247","EIEE2","STK9"],"Ensembl":"ENSG00000008086","Gene description":"Cyclin dependent kinase like 5","Uniprot":["O76039"],"Chromosome":"X","Position":"18425583-18653629","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"216.6","Horizontal cells":"80.8","Inhibitory neurons":"116.1","Oligodendrocytes":"79.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"5.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"granulocytes":"5.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"10.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002847","CAB011577"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB011577":"AB_727019","HPA002847":"AB_1080107"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.54e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Tissue RNA - adipose tissue [nTPM]":"2.0","Tissue RNA - adrenal gland [nTPM]":"1.6","Tissue RNA - amygdala [nTPM]":"4.9","Tissue RNA - appendix [nTPM]":"1.1","Tissue RNA - basal ganglia [nTPM]":"6.7","Tissue RNA - bone marrow [nTPM]":"2.5","Tissue RNA - breast [nTPM]":"2.5","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"11.7","Tissue RNA - cervix [nTPM]":"3.9","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.9","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"2.6","Tissue RNA - epididymis [nTPM]":"1.9","Tissue RNA - esophagus [nTPM]":"3.5","Tissue RNA - fallopian tube [nTPM]":"1.7","Tissue RNA - gallbladder [nTPM]":"1.8","Tissue RNA - heart muscle [nTPM]":"3.8","Tissue RNA - hippocampal formation [nTPM]":"6.8","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"3.5","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"4.6","Tissue RNA - lymph node [nTPM]":"0.8","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"2.5","Tissue RNA - ovary [nTPM]":"3.8","Tissue RNA - pancreas [nTPM]":"2.4","Tissue RNA - parathyroid gland [nTPM]":"2.4","Tissue RNA - pituitary gland [nTPM]":"1.7","Tissue RNA - placenta [nTPM]":"3.2","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"3.6","Tissue RNA - rectum [nTPM]":"1.2","Tissue RNA - retina [nTPM]":"12.2","Tissue RNA - salivary gland [nTPM]":"2.2","Tissue RNA - seminal vesicle [nTPM]":"2.3","Tissue RNA - skeletal muscle [nTPM]":"1.7","Tissue RNA - skin 1 [nTPM]":"2.2","Tissue RNA - small intestine [nTPM]":"0.9","Tissue RNA - smooth muscle [nTPM]":"2.5","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"1.2","Tissue RNA - stomach 1 [nTPM]":"2.4","Tissue RNA - testis [nTPM]":"7.1","Tissue RNA - thalamus [nTPM]":"5.7","Tissue RNA - thymus [nTPM]":"1.7","Tissue RNA - thyroid gland [nTPM]":"3.0","Tissue RNA - tongue [nTPM]":"2.0","Tissue RNA - tonsil [nTPM]":"1.1","Tissue RNA - urinary bladder [nTPM]":"2.7","Tissue RNA - vagina [nTPM]":"3.4","Tissue RNA - white matter [nTPM]":"5.4","Cell RNA - A-431 [nTPM]":"1.1","Cell RNA - A549 [nTPM]":"10.0","Cell RNA - AF22 [nTPM]":"2.6","Cell RNA - AN3-CA [nTPM]":"2.2","Cell RNA - ASC diff [nTPM]":"2.4","Cell RNA - ASC TERT1 [nTPM]":"3.6","Cell RNA - BEWO [nTPM]":"1.7","Cell RNA - BJ [nTPM]":"1.7","Cell RNA - BJ hTERT+ [nTPM]":"3.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.5","Cell RNA - CACO-2 [nTPM]":"3.3","Cell RNA - CAPAN-2 [nTPM]":"1.5","Cell RNA - Daudi [nTPM]":"1.5","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"1.0","Cell RNA - GAMG [nTPM]":"4.5","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"3.2","Cell RNA - HBEC3-KT [nTPM]":"1.8","Cell RNA - HBF TERT88 [nTPM]":"4.3","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"1.7","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"5.5","Cell RNA - Hep G2 [nTPM]":"2.1","Cell RNA - HHSteC [nTPM]":"1.1","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.7","Cell RNA - HSkMC [nTPM]":"1.7","Cell RNA - hTCEpi [nTPM]":"1.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.4","Cell RNA - hTERT-HME1 [nTPM]":"4.9","Cell RNA - hTERT-RPE1 [nTPM]":"1.3","Cell RNA - HUVEC TERT2 [nTPM]":"1.0","Cell RNA - JURKAT [nTPM]":"1.6","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"1.5","Cell RNA - LHCN-M2 [nTPM]":"2.7","Cell RNA - MCF7 [nTPM]":"1.0","Cell RNA - MOLT-4 [nTPM]":"0.6","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"5.2","Cell RNA - OE19 [nTPM]":"0.9","Cell RNA - PC-3 [nTPM]":"2.3","Cell RNA - REH [nTPM]":"0.6","Cell RNA - RH-30 [nTPM]":"3.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"1.8","Cell RNA - RT4 [nTPM]":"7.1","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"3.2","Cell RNA - SiHa [nTPM]":"2.7","Cell RNA - SK-BR-3 [nTPM]":"0.9","Cell RNA - SK-MEL-30 [nTPM]":"1.5","Cell RNA - SuSa [nTPM]":"4.4","Cell RNA - T-47d [nTPM]":"1.3","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"6.2","Cell RNA - U-138 MG [nTPM]":"2.5","Cell RNA - U-2 OS [nTPM]":"1.7","Cell RNA - U-2197 [nTPM]":"5.5","Cell RNA - U-251 MG [nTPM]":"1.3","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"1.4","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"3.0","Blood RNA - basophil [nTPM]":"5.7","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"1.1","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"2.0","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"4.9","Brain RNA - basal ganglia [nTPM]":"6.7","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"11.7","Brain RNA - hippocampal formation [nTPM]":"6.8","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"2.5","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"5.7","Brain RNA - white matter [nTPM]":"5.4","Single Cell Type RNA - Adipocytes [nTPM]":"9.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"24.8","Single Cell Type RNA - Astrocytes [nTPM]":"37.5","Single Cell Type RNA - B-cells [nTPM]":"2.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"19.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"5.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.4","Single Cell Type RNA - dendritic cells [nTPM]":"3.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.7","Single Cell Type RNA - Early spermatids [nTPM]":"34.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.4","Single Cell Type RNA - Endothelial cells [nTPM]":"6.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"216.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.1","Single Cell Type RNA - Fibroblasts [nTPM]":"7.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.9","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"3.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"3.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.2","Single Cell Type RNA - Horizontal cells [nTPM]":"80.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"116.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.6","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.4","Single Cell Type RNA - Langerhans cells [nTPM]":"0.5","Single Cell Type RNA - Late spermatids [nTPM]":"55.3","Single Cell Type RNA - Leydig cells [nTPM]":"5.9","Single Cell Type RNA - Macrophages [nTPM]":"4.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"34.7","Single Cell Type RNA - monocytes [nTPM]":"4.6","Single Cell Type RNA - Muller glia cells [nTPM]":"23.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"41.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"79.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.8","Single Cell Type RNA - Peritubular cells [nTPM]":"5.3","Single Cell Type RNA - Plasma cells [nTPM]":"4.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"20.4","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.4","Single Cell Type RNA - Spermatocytes [nTPM]":"5.8","Single Cell Type RNA - Spermatogonia [nTPM]":"10.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"47.3","Single Cell Type RNA - T-cells [nTPM]":"2.3","Single Cell Type RNA - Theca cells [nTPM]":"5.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.8","Single Cell Type RNA - Urothelial cells [nTPM]":"22.9"},{"Gene":"CDKN3","Gene synonym":["CDI1","KAP"],"Ensembl":"ENSG00000100526","Gene description":"Cyclin dependent kinase inhibitor 3","Uniprot":["Q16667"],"Chromosome":"14","Position":"54396849-54420218","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"testis":"207.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"2630.9","Late spermatids":"659.4","Spermatocytes":"606.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"18.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"NK-cells":"6.4","T-cells":"18.8"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005285","HPA039311","HPA058874"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB005285":"AB_2078884","HPA039311":null,"HPA058874":"AB_2683842"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.52e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.46e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.4","Tissue RNA - adrenal gland [nTPM]":"1.6","Tissue RNA - amygdala [nTPM]":"2.8","Tissue RNA - appendix [nTPM]":"12.2","Tissue RNA - basal ganglia [nTPM]":"2.7","Tissue RNA - bone marrow [nTPM]":"43.4","Tissue RNA - breast [nTPM]":"3.4","Tissue RNA - cerebellum [nTPM]":"5.0","Tissue RNA - cerebral cortex [nTPM]":"4.2","Tissue RNA - cervix [nTPM]":"2.2","Tissue RNA - choroid plexus [nTPM]":"3.4","Tissue RNA - colon [nTPM]":"13.9","Tissue RNA - duodenum [nTPM]":"12.4","Tissue RNA - endometrium 1 [nTPM]":"2.8","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"10.2","Tissue RNA - fallopian tube [nTPM]":"1.3","Tissue RNA - gallbladder [nTPM]":"2.9","Tissue RNA - heart muscle [nTPM]":"5.3","Tissue RNA - hippocampal formation [nTPM]":"2.9","Tissue RNA - hypothalamus [nTPM]":"3.1","Tissue RNA - kidney [nTPM]":"2.0","Tissue RNA - liver [nTPM]":"2.4","Tissue RNA - lung [nTPM]":"2.1","Tissue RNA - lymph node [nTPM]":"28.4","Tissue RNA - medulla oblongata [nTPM]":"2.5","Tissue RNA - midbrain [nTPM]":"2.7","Tissue RNA - ovary [nTPM]":"1.3","Tissue RNA - pancreas [nTPM]":"1.1","Tissue RNA - parathyroid gland [nTPM]":"0.5","Tissue RNA - pituitary gland [nTPM]":"1.6","Tissue RNA - placenta [nTPM]":"6.7","Tissue RNA - pons [nTPM]":"3.3","Tissue RNA - prostate [nTPM]":"1.6","Tissue RNA - rectum [nTPM]":"16.9","Tissue RNA - retina [nTPM]":"2.6","Tissue RNA - salivary gland [nTPM]":"3.3","Tissue RNA - seminal vesicle [nTPM]":"0.7","Tissue RNA - skeletal muscle [nTPM]":"3.0","Tissue RNA - skin 1 [nTPM]":"5.9","Tissue RNA - small intestine [nTPM]":"12.6","Tissue RNA - smooth muscle [nTPM]":"7.4","Tissue RNA - spinal cord [nTPM]":"2.1","Tissue RNA - spleen [nTPM]":"4.9","Tissue RNA - stomach 1 [nTPM]":"5.0","Tissue RNA - testis [nTPM]":"207.0","Tissue RNA - thalamus [nTPM]":"3.5","Tissue RNA - thymus [nTPM]":"30.9","Tissue RNA - thyroid gland [nTPM]":"1.7","Tissue RNA - tongue [nTPM]":"4.1","Tissue RNA - tonsil [nTPM]":"30.0","Tissue RNA - urinary bladder [nTPM]":"5.8","Tissue RNA - vagina [nTPM]":"4.1","Tissue RNA - white matter [nTPM]":"2.6","Cell RNA - A-431 [nTPM]":"276.7","Cell RNA - A549 [nTPM]":"102.5","Cell RNA - AF22 [nTPM]":"74.0","Cell RNA - AN3-CA [nTPM]":"78.2","Cell RNA - ASC diff [nTPM]":"12.5","Cell RNA - ASC TERT1 [nTPM]":"15.3","Cell RNA - BEWO [nTPM]":"46.5","Cell RNA - BJ [nTPM]":"63.1","Cell RNA - BJ hTERT+ [nTPM]":"97.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"135.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"146.9","Cell RNA - CACO-2 [nTPM]":"81.8","Cell RNA - CAPAN-2 [nTPM]":"136.5","Cell RNA - Daudi [nTPM]":"139.9","Cell RNA - EFO-21 [nTPM]":"44.4","Cell RNA - fHDF\/TERT166 [nTPM]":"96.7","Cell RNA - GAMG [nTPM]":"135.9","Cell RNA - HaCaT [nTPM]":"195.9","Cell RNA - HAP1 [nTPM]":"114.6","Cell RNA - HBEC3-KT [nTPM]":"78.3","Cell RNA - HBF TERT88 [nTPM]":"245.6","Cell RNA - HDLM-2 [nTPM]":"169.5","Cell RNA - HEK 293 [nTPM]":"59.3","Cell RNA - HEL [nTPM]":"65.8","Cell RNA - HeLa [nTPM]":"69.0","Cell RNA - Hep G2 [nTPM]":"126.8","Cell RNA - HHSteC [nTPM]":"10.1","Cell RNA - HL-60 [nTPM]":"86.2","Cell RNA - HMC-1 [nTPM]":"47.6","Cell RNA - HSkMC [nTPM]":"5.4","Cell RNA - hTCEpi [nTPM]":"4.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"84.3","Cell RNA - hTERT-HME1 [nTPM]":"138.3","Cell RNA - hTERT-RPE1 [nTPM]":"44.4","Cell RNA - HUVEC TERT2 [nTPM]":"88.4","Cell RNA - JURKAT [nTPM]":"129.8","Cell RNA - K-562 [nTPM]":"36.1","Cell RNA - Karpas-707 [nTPM]":"162.2","Cell RNA - LHCN-M2 [nTPM]":"159.8","Cell RNA - MCF7 [nTPM]":"186.9","Cell RNA - MOLT-4 [nTPM]":"118.1","Cell RNA - NB-4 [nTPM]":"67.9","Cell RNA - NTERA-2 [nTPM]":"27.9","Cell RNA - OE19 [nTPM]":"254.7","Cell RNA - PC-3 [nTPM]":"216.4","Cell RNA - REH [nTPM]":"72.7","Cell RNA - RH-30 [nTPM]":"66.6","Cell RNA - RPMI-8226 [nTPM]":"29.7","Cell RNA - RPTEC TERT1 [nTPM]":"70.5","Cell RNA - RT4 [nTPM]":"56.9","Cell RNA - SCLC-21H [nTPM]":"30.6","Cell RNA - SH-SY5Y [nTPM]":"42.0","Cell RNA - SiHa [nTPM]":"118.7","Cell RNA - SK-BR-3 [nTPM]":"67.4","Cell RNA - SK-MEL-30 [nTPM]":"52.5","Cell RNA - SuSa [nTPM]":"54.6","Cell RNA - T-47d [nTPM]":"142.9","Cell RNA - THP-1 [nTPM]":"69.4","Cell RNA - TIME [nTPM]":"33.0","Cell RNA - U-138 MG [nTPM]":"59.2","Cell RNA - U-2 OS [nTPM]":"195.8","Cell RNA - U-2197 [nTPM]":"91.7","Cell RNA - U-251 MG [nTPM]":"155.0","Cell RNA - U-266\/70 [nTPM]":"38.6","Cell RNA - U-266\/84 [nTPM]":"47.4","Cell RNA - U-698 [nTPM]":"91.4","Cell RNA - U-87 MG [nTPM]":"98.6","Cell RNA - U-937 [nTPM]":"120.4","Cell RNA - WM-115 [nTPM]":"110.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"1.3","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"1.7","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"2.1","Blood RNA - memory CD4 T-cell [nTPM]":"5.5","Blood RNA - memory CD8 T-cell [nTPM]":"4.8","Blood RNA - myeloid DC [nTPM]":"1.8","Blood RNA - naive B-cell [nTPM]":"0.9","Blood RNA - naive CD4 T-cell [nTPM]":"2.9","Blood RNA - naive CD8 T-cell [nTPM]":"2.3","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"6.4","Blood RNA - non-classical monocyte [nTPM]":"1.2","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"18.8","Blood RNA - total PBMC [nTPM]":"3.1","Brain RNA - amygdala [nTPM]":"2.8","Brain RNA - basal ganglia [nTPM]":"2.7","Brain RNA - cerebellum [nTPM]":"5.0","Brain RNA - cerebral cortex [nTPM]":"4.2","Brain RNA - hippocampal formation [nTPM]":"2.9","Brain RNA - hypothalamus [nTPM]":"3.1","Brain RNA - medulla oblongata [nTPM]":"2.5","Brain RNA - midbrain [nTPM]":"2.7","Brain RNA - pons [nTPM]":"3.3","Brain RNA - spinal cord [nTPM]":"2.1","Brain RNA - thalamus [nTPM]":"3.5","Brain RNA - white matter [nTPM]":"2.6","Single Cell Type RNA - Adipocytes [nTPM]":"1.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"10.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"3.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"42.6","Single Cell Type RNA - dendritic cells [nTPM]":"2.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.5","Single Cell Type RNA - Early spermatids [nTPM]":"2630.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.5","Single Cell Type RNA - Endothelial cells [nTPM]":"6.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.8","Single Cell Type RNA - Erythroid cells [nTPM]":"125.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"35.0","Single Cell Type RNA - Fibroblasts [nTPM]":"10.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.5","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"31.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"3.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"37.7","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.9","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"9.8","Single Cell Type RNA - Langerhans cells [nTPM]":"8.8","Single Cell Type RNA - Late spermatids [nTPM]":"659.4","Single Cell Type RNA - Leydig cells [nTPM]":"21.5","Single Cell Type RNA - Macrophages [nTPM]":"8.9","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"2.9","Single Cell Type RNA - Muller glia cells [nTPM]":"1.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.9","Single Cell Type RNA - Paneth cells [nTPM]":"7.2","Single Cell Type RNA - Peritubular cells [nTPM]":"10.5","Single Cell Type RNA - Plasma cells [nTPM]":"41.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.5","Single Cell Type RNA - Spermatocytes [nTPM]":"606.9","Single Cell Type RNA - Spermatogonia [nTPM]":"39.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.1","Single Cell Type RNA - T-cells [nTPM]":"8.3","Single Cell Type RNA - Theca cells [nTPM]":"3.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"31.2","Single Cell Type RNA - Urothelial cells [nTPM]":"5.3"},{"Gene":"CEL","Gene synonym":["BSSL","MODY8"],"Ensembl":"ENSG00000170835","Gene description":"Carboxyl ester lipase","Uniprot":["P19835"],"Chromosome":"9","Position":"133061981-133071861","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted secreted proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase","Serine esterase"],"Disease involvement":["Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"548","RNA tissue specific nTPM":{"pancreas":"110578.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Breast glandular cells":"390.7","Exocrine glandular cells":"943.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"29","RNA cancer specific FPKM":{"pancreatic cancer":"469.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"JURKAT":"7.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008023","HPA052701"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to digestive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 30: Mammary glandular cells - Lactation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA008023":"AB_1846509","HPA052701":"AB_2681921"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.14e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.0","Tissue RNA - adrenal gland [nTPM]":"3.0","Tissue RNA - amygdala [nTPM]":"3.1","Tissue RNA - appendix [nTPM]":"2.2","Tissue RNA - basal ganglia [nTPM]":"3.2","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"10.4","Tissue RNA - cerebellum [nTPM]":"4.8","Tissue RNA - cerebral cortex [nTPM]":"4.5","Tissue RNA - cervix [nTPM]":"6.4","Tissue RNA - choroid plexus [nTPM]":"13.5","Tissue RNA - colon [nTPM]":"2.9","Tissue RNA - duodenum [nTPM]":"21.6","Tissue RNA - endometrium 1 [nTPM]":"3.2","Tissue RNA - epididymis [nTPM]":"200.8","Tissue RNA - esophagus [nTPM]":"7.1","Tissue RNA - fallopian tube [nTPM]":"11.1","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"22.0","Tissue RNA - hippocampal formation [nTPM]":"4.1","Tissue RNA - hypothalamus [nTPM]":"2.7","Tissue RNA - kidney [nTPM]":"7.5","Tissue RNA - liver [nTPM]":"6.4","Tissue RNA - lung [nTPM]":"2.1","Tissue RNA - lymph node [nTPM]":"4.1","Tissue RNA - medulla oblongata [nTPM]":"2.9","Tissue RNA - midbrain [nTPM]":"2.8","Tissue RNA - ovary [nTPM]":"57.2","Tissue RNA - pancreas [nTPM]":"110578.0","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"201.7","Tissue RNA - placenta [nTPM]":"7.1","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"5.1","Tissue RNA - rectum [nTPM]":"1.3","Tissue RNA - retina [nTPM]":"1.1","Tissue RNA - salivary gland [nTPM]":"19.9","Tissue RNA - seminal vesicle [nTPM]":"3.3","Tissue RNA - skeletal muscle [nTPM]":"2.2","Tissue RNA - skin 1 [nTPM]":"5.5","Tissue RNA - small intestine [nTPM]":"9.2","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"2.5","Tissue RNA - spleen [nTPM]":"3.4","Tissue RNA - stomach 1 [nTPM]":"18.5","Tissue RNA - testis [nTPM]":"2.5","Tissue RNA - thalamus [nTPM]":"3.0","Tissue RNA - thymus [nTPM]":"1.9","Tissue RNA - thyroid gland [nTPM]":"2.5","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"0.6","Tissue RNA - urinary bladder [nTPM]":"3.4","Tissue RNA - vagina [nTPM]":"3.4","Tissue RNA - white matter [nTPM]":"3.0","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"3.1","Cell RNA - AN3-CA [nTPM]":"1.9","Cell RNA - ASC diff [nTPM]":"1.0","Cell RNA - ASC TERT1 [nTPM]":"0.7","Cell RNA - BEWO [nTPM]":"3.1","Cell RNA - BJ [nTPM]":"0.6","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.6","Cell RNA - CACO-2 [nTPM]":"0.9","Cell RNA - CAPAN-2 [nTPM]":"0.6","Cell RNA - Daudi [nTPM]":"0.9","Cell RNA - EFO-21 [nTPM]":"1.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.6","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"2.2","Cell RNA - HAP1 [nTPM]":"0.7","Cell RNA - HBEC3-KT [nTPM]":"5.9","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"1.9","Cell RNA - HEK 293 [nTPM]":"1.2","Cell RNA - HEL [nTPM]":"1.6","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"2.1","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"0.7","Cell RNA - HMC-1 [nTPM]":"5.9","Cell RNA - HSkMC [nTPM]":"1.5","Cell RNA - hTCEpi [nTPM]":"3.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.5","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"1.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.6","Cell RNA - JURKAT [nTPM]":"7.5","Cell RNA - K-562 [nTPM]":"1.0","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"1.3","Cell RNA - MOLT-4 [nTPM]":"0.9","Cell RNA - NB-4 [nTPM]":"3.2","Cell RNA - NTERA-2 [nTPM]":"5.2","Cell RNA - OE19 [nTPM]":"0.7","Cell RNA - PC-3 [nTPM]":"1.0","Cell RNA - REH [nTPM]":"1.8","Cell RNA - RH-30 [nTPM]":"0.9","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.4","Cell RNA - RT4 [nTPM]":"2.7","Cell RNA - SCLC-21H [nTPM]":"5.3","Cell RNA - SH-SY5Y [nTPM]":"1.3","Cell RNA - SiHa [nTPM]":"0.7","Cell RNA - SK-BR-3 [nTPM]":"0.7","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"4.5","Cell RNA - T-47d [nTPM]":"1.0","Cell RNA - THP-1 [nTPM]":"2.9","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"1.5","Cell RNA - U-2 OS [nTPM]":"2.0","Cell RNA - U-2197 [nTPM]":"1.7","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"3.4","Cell RNA - U-698 [nTPM]":"0.7","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"1.6","Cell RNA - WM-115 [nTPM]":"0.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.1","Brain RNA - basal ganglia [nTPM]":"3.2","Brain RNA - cerebellum [nTPM]":"4.8","Brain RNA - cerebral cortex [nTPM]":"4.5","Brain RNA - hippocampal formation [nTPM]":"4.1","Brain RNA - hypothalamus [nTPM]":"2.7","Brain RNA - medulla oblongata [nTPM]":"2.9","Brain RNA - midbrain [nTPM]":"2.8","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"2.5","Brain RNA - thalamus [nTPM]":"3.0","Brain RNA - white matter [nTPM]":"3.0","Single Cell Type RNA - Adipocytes [nTPM]":"1.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"1.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"390.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"1.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"62.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.8","Single Cell Type RNA - Endothelial cells [nTPM]":"0.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"943.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"4.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.8","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"3.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"6.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"27.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"6.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.1","Single Cell Type RNA - Urothelial cells [nTPM]":"3.0"},{"Gene":"CELA2A","Gene synonym":["ELA2A"],"Ensembl":"ENSG00000142615","Gene description":"Chymotrypsin like elastase 2A","Uniprot":["P08217"],"Chromosome":"1","Position":"15456728-15472091","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Diabetes mellitus","Disease variant","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"2325","RNA tissue specific nTPM":{"pancreas":"162732.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"34","RNA single cell type specific nTPM":{"Exocrine glandular cells":"7828.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"3818","RNA cancer specific FPKM":{"pancreatic cancer":"463.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"1.2"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to digestive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2700000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 1: Pancreatic cells - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.9","Tissue RNA - adrenal gland [nTPM]":"5.5","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"2.6","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"1.1","Tissue RNA - breast [nTPM]":"4.4","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"3.9","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"2.0","Tissue RNA - duodenum [nTPM]":"18.5","Tissue RNA - endometrium 1 [nTPM]":"2.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"2.3","Tissue RNA - fallopian tube [nTPM]":"1.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"26.9","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"1.6","Tissue RNA - liver [nTPM]":"5.8","Tissue RNA - lung [nTPM]":"1.2","Tissue RNA - lymph node [nTPM]":"4.3","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"70.0","Tissue RNA - pancreas [nTPM]":"162732.5","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.3","Tissue RNA - placenta [nTPM]":"10.2","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"2.7","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"28.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"1.6","Tissue RNA - skin 1 [nTPM]":"2.2","Tissue RNA - small intestine [nTPM]":"8.7","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"2.2","Tissue RNA - stomach 1 [nTPM]":"15.4","Tissue RNA - testis [nTPM]":"2.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"1.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.9","Tissue RNA - vagina [nTPM]":"1.3","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"1.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7828.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"20.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"227.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"1.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"CELSR1","Gene synonym":["ADGRC1","CDHF9","FMI2","HFMI2","ME2"],"Ensembl":"ENSG00000075275","Gene description":"Cadherin EGF LAG seven-pass G-type receptor 1","Uniprot":["Q9NYQ6"],"Chromosome":"22","Position":"46360834-46537620","Protein class":["Disease related genes","G-protein coupled receptors","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Developmental protein","G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"31.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"41.7","Basal respiratory cells":"28.1","Club cells":"31.1","Endometrial ciliated cells":"31.8","Glandular and luminal cells":"42.6","Respiratory ciliated cells":"60.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"memory B-cell":"2.2","naive B-cell":"1.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"B-cells":"2.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"68.4","RPTEC TERT1":"48.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052976","HPA060521"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"280000","Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA052976":"AB_2682004","HPA060521":"AB_2684303"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.7","Tissue RNA - adrenal gland [nTPM]":"0.8","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"3.1","Tissue RNA - basal ganglia [nTPM]":"0.9","Tissue RNA - bone marrow [nTPM]":"0.8","Tissue RNA - breast [nTPM]":"7.8","Tissue RNA - cerebellum [nTPM]":"1.5","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"9.9","Tissue RNA - choroid plexus [nTPM]":"1.2","Tissue RNA - colon [nTPM]":"1.6","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"3.7","Tissue RNA - epididymis [nTPM]":"10.2","Tissue RNA - esophagus [nTPM]":"11.5","Tissue RNA - fallopian tube [nTPM]":"15.4","Tissue RNA - gallbladder [nTPM]":"1.4","Tissue RNA - heart muscle [nTPM]":"3.4","Tissue RNA - hippocampal formation [nTPM]":"1.0","Tissue RNA - hypothalamus [nTPM]":"0.4","Tissue RNA - kidney [nTPM]":"17.1","Tissue RNA - liver [nTPM]":"5.2","Tissue RNA - lung [nTPM]":"12.5","Tissue RNA - lymph node [nTPM]":"5.9","Tissue RNA - medulla oblongata [nTPM]":"2.4","Tissue RNA - midbrain [nTPM]":"3.9","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"2.6","Tissue RNA - parathyroid gland [nTPM]":"6.3","Tissue RNA - pituitary gland [nTPM]":"2.4","Tissue RNA - placenta [nTPM]":"1.0","Tissue RNA - pons [nTPM]":"1.4","Tissue RNA - prostate [nTPM]":"5.0","Tissue RNA - rectum [nTPM]":"1.8","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"12.0","Tissue RNA - seminal vesicle [nTPM]":"3.9","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"31.5","Tissue RNA - small intestine [nTPM]":"1.6","Tissue RNA - smooth muscle [nTPM]":"1.1","Tissue RNA - spinal cord [nTPM]":"1.6","Tissue RNA - spleen [nTPM]":"3.3","Tissue RNA - stomach 1 [nTPM]":"5.4","Tissue RNA - testis [nTPM]":"1.3","Tissue RNA - thalamus [nTPM]":"2.2","Tissue RNA - thymus [nTPM]":"2.4","Tissue RNA - thyroid gland [nTPM]":"3.7","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"7.9","Tissue RNA - urinary bladder [nTPM]":"3.9","Tissue RNA - vagina [nTPM]":"3.7","Tissue RNA - white matter [nTPM]":"1.0","Cell RNA - A-431 [nTPM]":"22.3","Cell RNA - A549 [nTPM]":"68.4","Cell RNA - AF22 [nTPM]":"11.3","Cell RNA - AN3-CA [nTPM]":"10.6","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"6.5","Cell RNA - BJ [nTPM]":"2.3","Cell RNA - BJ hTERT+ [nTPM]":"3.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.3","Cell RNA - CACO-2 [nTPM]":"21.7","Cell RNA - CAPAN-2 [nTPM]":"21.9","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"32.1","Cell RNA - fHDF\/TERT166 [nTPM]":"1.3","Cell RNA - GAMG [nTPM]":"22.0","Cell RNA - HaCaT [nTPM]":"35.0","Cell RNA - HAP1 [nTPM]":"7.5","Cell RNA - HBEC3-KT [nTPM]":"28.7","Cell RNA - HBF TERT88 [nTPM]":"2.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"10.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"25.6","Cell RNA - Hep G2 [nTPM]":"2.0","Cell RNA - HHSteC [nTPM]":"1.0","Cell RNA - HL-60 [nTPM]":"3.2","Cell RNA - HMC-1 [nTPM]":"1.8","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"43.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"26.2","Cell RNA - hTERT-RPE1 [nTPM]":"31.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.4","Cell RNA - JURKAT [nTPM]":"1.7","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"38.4","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"11.9","Cell RNA - NTERA-2 [nTPM]":"4.5","Cell RNA - OE19 [nTPM]":"12.1","Cell RNA - PC-3 [nTPM]":"8.1","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"8.1","Cell RNA - RPTEC TERT1 [nTPM]":"48.7","Cell RNA - RT4 [nTPM]":"13.5","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"0.9","Cell RNA - SiHa [nTPM]":"16.1","Cell RNA - SK-BR-3 [nTPM]":"17.3","Cell RNA - SK-MEL-30 [nTPM]":"3.7","Cell RNA - SuSa [nTPM]":"7.9","Cell RNA - T-47d [nTPM]":"39.7","Cell RNA - THP-1 [nTPM]":"16.7","Cell RNA - TIME [nTPM]":"0.9","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"10.6","Cell RNA - U-266\/84 [nTPM]":"1.1","Cell RNA - U-698 [nTPM]":"10.5","Cell RNA - U-87 MG [nTPM]":"15.2","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"12.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"2.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"1.9","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.9","Brain RNA - cerebellum [nTPM]":"1.5","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"1.0","Brain RNA - hypothalamus [nTPM]":"0.4","Brain RNA - medulla oblongata [nTPM]":"2.4","Brain RNA - midbrain [nTPM]":"3.9","Brain RNA - pons [nTPM]":"1.4","Brain RNA - spinal cord [nTPM]":"1.6","Brain RNA - thalamus [nTPM]":"2.2","Brain RNA - white matter [nTPM]":"1.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"5.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"28.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"31.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - dendritic cells [nTPM]":"2.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.8","Single Cell Type RNA - Early spermatids [nTPM]":"2.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"31.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.0","Single Cell Type RNA - Endothelial cells [nTPM]":"5.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.9","Single Cell Type RNA - Fibroblasts [nTPM]":"1.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"42.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"1.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.8","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"4.1","Single Cell Type RNA - Late spermatids [nTPM]":"10.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.1","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"1.1","Single Cell Type RNA - Muller glia cells [nTPM]":"1.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"60.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.7","Single Cell Type RNA - Urothelial cells [nTPM]":"5.1"},{"Gene":"CERS3","Gene synonym":["LASS3","MGC27091"],"Ensembl":"ENSG00000154227","Gene description":"Ceramide synthase 3","Uniprot":["Q8IU89"],"Chromosome":"15","Position":"100400395-100544995","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"55.1","skin 1":"64.0","vagina":"30.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Basal keratinocytes":"18.9","Basal squamous epithelial cells":"39.3","Early spermatids":"23.5","Late spermatids":"17.5","Spermatocytes":"28.2","Squamous epithelial cells":"48.3","Suprabasal keratinocytes":"50.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"14.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"hTCEpi":"65.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006092","HPA024356"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 61: Squamous epithelial cells - Keratinization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA006092":"AB_1079236","HPA024356":"AB_1852721"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"3.3","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"15.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"55.1","Tissue RNA - fallopian tube [nTPM]":"0.7","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.4","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.6","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"8.4","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.6","Tissue RNA - skin 1 [nTPM]":"64.0","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"18.3","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"16.0","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"30.3","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"5.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"10.4","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"65.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.6","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"1.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"39.3","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"4.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"23.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"2.1","Single Cell Type RNA - Late spermatids [nTPM]":"17.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"28.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"48.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"50.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"6.0"},{"Gene":"CETP","Gene synonym":["BPIFF"],"Ensembl":"ENSG00000087237","Gene description":"Cholesteryl ester transfer protein","Uniprot":["P11597"],"Chromosome":"16","Position":"56961923-56983845","Protein class":["Candidate cardiovascular disease genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins","Transporters"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Lipid transport","Steroid metabolism","Sterol metabolism","Transport"],"Molecular function":null,"Disease involvement":["Atherosclerosis","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"adipose tissue":"33.5","liver":"43.0","lymphoid tissue":"59.6","placenta":"36.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Adipocytes":"48.6","Hepatic stellate cells":"75.0","Kupffer cells":"142.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"2.3","plasmacytoid DC":"3.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"2.3","HUVEC TERT2":"4.7","TIME":"2.8"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":2470000000,"Blood concentration - Conc. blood MS [pg\/L]":"360000000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.17e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.97e-2"},"Tissue RNA - adipose tissue [nTPM]":"33.5","Tissue RNA - adrenal gland [nTPM]":"2.0","Tissue RNA - amygdala [nTPM]":"0.7","Tissue RNA - appendix [nTPM]":"3.8","Tissue RNA - basal ganglia [nTPM]":"0.7","Tissue RNA - bone marrow [nTPM]":"5.7","Tissue RNA - breast [nTPM]":"6.6","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"1.4","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"0.6","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"0.7","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"4.0","Tissue RNA - heart muscle [nTPM]":"0.7","Tissue RNA - hippocampal formation [nTPM]":"0.6","Tissue RNA - hypothalamus [nTPM]":"0.8","Tissue RNA - kidney [nTPM]":"3.7","Tissue RNA - liver [nTPM]":"43.0","Tissue RNA - lung [nTPM]":"2.8","Tissue RNA - lymph node [nTPM]":"43.3","Tissue RNA - medulla oblongata [nTPM]":"1.1","Tissue RNA - midbrain [nTPM]":"0.8","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.5","Tissue RNA - parathyroid gland [nTPM]":"1.8","Tissue RNA - pituitary gland [nTPM]":"3.1","Tissue RNA - placenta [nTPM]":"36.2","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.7","Tissue RNA - seminal vesicle [nTPM]":"0.5","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"1.9","Tissue RNA - smooth muscle [nTPM]":"0.8","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"59.6","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.9","Tissue RNA - thymus [nTPM]":"2.3","Tissue RNA - thyroid gland [nTPM]":"5.2","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"7.6","Tissue RNA - urinary bladder [nTPM]":"1.5","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.8","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"2.3","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.6","Cell RNA - HHSteC [nTPM]":"0.8","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"4.7","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.8","Cell RNA - TIME [nTPM]":"2.8","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"2.3","Blood RNA - plasmacytoid DC [nTPM]":"3.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"0.7","Brain RNA - basal ganglia [nTPM]":"0.7","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"1.4","Brain RNA - hippocampal formation [nTPM]":"0.6","Brain RNA - hypothalamus [nTPM]":"0.8","Brain RNA - medulla oblongata [nTPM]":"1.1","Brain RNA - midbrain [nTPM]":"0.8","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"0.9","Brain RNA - white matter [nTPM]":"0.8","Single Cell Type RNA - Adipocytes [nTPM]":"48.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"13.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"75.0","Single Cell Type RNA - Hepatocytes [nTPM]":"1.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"142.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"2.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"1.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CFB","Gene synonym":["BF","BFD","H2-Bf"],"Ensembl":"ENSG00000243649","Gene description":"Complement factor B","Uniprot":["P00751"],"Chromosome":"6","Position":"31945650-31952084","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Complement alternate pathway","Immunity","Innate immunity"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Age-related macular degeneration","Disease variant","Hemolytic uremic syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"18","RNA tissue specific nTPM":{"liver":"2613.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"873.6","Exocrine glandular cells":"197.3","Hepatocytes":"284.0","Pancreatic endocrine cells":"318.0","Proximal enterocytes":"139.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"78.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"15.0","ASC TERT1":"23.0","EFO-21":"25.1","fHDF\/TERT166":"14.1","HSkMC":"19.1","U-87 MG":"10.1"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000951","HPA001817","HPA001832","CAB016381"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Vesicles","Cell Junctions"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":879000000,"Blood concentration - Conc. blood MS [pg\/L]":"120000000000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 1: Pancreatic cells - Digestion","Subcellular main location":["Endoplasmic reticulum","Vesicles"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"CAB016381":"AB_627562","HPA000951":"AB_2797216","HPA001817":"AB_1078779","HPA001832":"AB_1078778"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.76e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.53e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Tissue RNA - adipose tissue [nTPM]":"143.7","Tissue RNA - adrenal gland [nTPM]":"18.0","Tissue RNA - amygdala [nTPM]":"3.6","Tissue RNA - appendix [nTPM]":"32.8","Tissue RNA - basal ganglia [nTPM]":"3.6","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"28.5","Tissue RNA - cerebellum [nTPM]":"3.4","Tissue RNA - cerebral cortex [nTPM]":"9.9","Tissue RNA - cervix [nTPM]":"16.3","Tissue RNA - choroid plexus [nTPM]":"3.9","Tissue RNA - colon [nTPM]":"22.3","Tissue RNA - duodenum [nTPM]":"28.1","Tissue RNA - endometrium 1 [nTPM]":"8.2","Tissue RNA - epididymis [nTPM]":"14.2","Tissue RNA - esophagus [nTPM]":"24.1","Tissue RNA - fallopian tube [nTPM]":"53.7","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"42.6","Tissue RNA - hippocampal formation [nTPM]":"3.7","Tissue RNA - hypothalamus [nTPM]":"3.4","Tissue RNA - kidney [nTPM]":"58.7","Tissue RNA - liver [nTPM]":"2613.2","Tissue RNA - lung [nTPM]":"39.2","Tissue RNA - lymph node [nTPM]":"4.2","Tissue RNA - medulla oblongata [nTPM]":"4.1","Tissue RNA - midbrain [nTPM]":"3.7","Tissue RNA - ovary [nTPM]":"9.9","Tissue RNA - pancreas [nTPM]":"51.8","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"17.7","Tissue RNA - placenta [nTPM]":"5.0","Tissue RNA - pons [nTPM]":"3.8","Tissue RNA - prostate [nTPM]":"60.3","Tissue RNA - rectum [nTPM]":"14.5","Tissue RNA - retina [nTPM]":"1.4","Tissue RNA - salivary gland [nTPM]":"43.3","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"3.0","Tissue RNA - skin 1 [nTPM]":"7.7","Tissue RNA - small intestine [nTPM]":"73.1","Tissue RNA - smooth muscle [nTPM]":"48.3","Tissue RNA - spinal cord [nTPM]":"3.4","Tissue RNA - spleen [nTPM]":"12.9","Tissue RNA - stomach 1 [nTPM]":"54.5","Tissue RNA - testis [nTPM]":"2.1","Tissue RNA - thalamus [nTPM]":"3.7","Tissue RNA - thymus [nTPM]":"1.9","Tissue RNA - thyroid gland [nTPM]":"15.5","Tissue RNA - tongue [nTPM]":"0.7","Tissue RNA - tonsil [nTPM]":"6.7","Tissue RNA - urinary bladder [nTPM]":"17.8","Tissue RNA - vagina [nTPM]":"9.2","Tissue RNA - white matter [nTPM]":"3.6","Cell RNA - A-431 [nTPM]":"0.5","Cell RNA - A549 [nTPM]":"1.9","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"15.0","Cell RNA - ASC TERT1 [nTPM]":"23.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"8.6","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"25.1","Cell RNA - fHDF\/TERT166 [nTPM]":"14.1","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"6.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"1.8","Cell RNA - HBF TERT88 [nTPM]":"1.2","Cell RNA - HDLM-2 [nTPM]":"1.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.7","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"1.0","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"19.1","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.6","Cell RNA - hTERT-HME1 [nTPM]":"0.5","Cell RNA - hTERT-RPE1 [nTPM]":"1.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"1.3","Cell RNA - RPTEC TERT1 [nTPM]":"1.7","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"1.3","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"3.4","Cell RNA - U-2 OS [nTPM]":"1.2","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"2.1","Cell RNA - U-698 [nTPM]":"1.0","Cell RNA - U-87 MG [nTPM]":"10.1","Cell RNA - U-937 [nTPM]":"0.6","Cell RNA - WM-115 [nTPM]":"0.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.6","Brain RNA - basal ganglia [nTPM]":"3.6","Brain RNA - cerebellum [nTPM]":"3.4","Brain RNA - cerebral cortex [nTPM]":"9.9","Brain RNA - hippocampal formation [nTPM]":"3.7","Brain RNA - hypothalamus [nTPM]":"3.4","Brain RNA - medulla oblongata [nTPM]":"4.1","Brain RNA - midbrain [nTPM]":"3.7","Brain RNA - pons [nTPM]":"3.8","Brain RNA - spinal cord [nTPM]":"3.4","Brain RNA - thalamus [nTPM]":"3.7","Brain RNA - white matter [nTPM]":"3.6","Single Cell Type RNA - Adipocytes [nTPM]":"1.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"64.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"44.3","Single Cell Type RNA - Club cells [nTPM]":"127.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"873.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"3.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"16.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"197.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"34.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"284.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.5","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"19.7","Single Cell Type RNA - Langerhans cells [nTPM]":"1.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"1.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"18.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"318.0","Single Cell Type RNA - Paneth cells [nTPM]":"10.6","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"139.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"75.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.6","Single Cell Type RNA - T-cells [nTPM]":"1.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.4","Single Cell Type RNA - Urothelial cells [nTPM]":"4.5"},{"Gene":"CFD","Gene synonym":["ADN","DF","PFD"],"Ensembl":"ENSG00000197766","Gene description":"Complement factor D","Uniprot":["P00746"],"Chromosome":"19","Position":"859664-863641","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted secreted proteins"],"Biological process":["Complement alternate pathway","Immunity","Innate immunity"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"1496.7","breast":"993.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Fibroblasts":"9365.5","Leydig cells":"5032.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"297.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"297.6"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"ASC diff":"197.4","THP-1":"342.2"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":732000000,"Blood concentration - Conc. blood MS [pg\/L]":"4400000000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.77e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.09e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.75e-2"},"Tissue RNA - adipose tissue [nTPM]":"1496.7","Tissue RNA - adrenal gland [nTPM]":"33.3","Tissue RNA - amygdala [nTPM]":"1.5","Tissue RNA - appendix [nTPM]":"9.6","Tissue RNA - basal ganglia [nTPM]":"1.6","Tissue RNA - bone marrow [nTPM]":"10.7","Tissue RNA - breast [nTPM]":"993.2","Tissue RNA - cerebellum [nTPM]":"1.2","Tissue RNA - cerebral cortex [nTPM]":"2.4","Tissue RNA - cervix [nTPM]":"597.4","Tissue RNA - choroid plexus [nTPM]":"3.7","Tissue RNA - colon [nTPM]":"324.8","Tissue RNA - duodenum [nTPM]":"23.5","Tissue RNA - endometrium 1 [nTPM]":"58.4","Tissue RNA - epididymis [nTPM]":"2.4","Tissue RNA - esophagus [nTPM]":"212.8","Tissue RNA - fallopian tube [nTPM]":"258.0","Tissue RNA - gallbladder [nTPM]":"9.6","Tissue RNA - heart muscle [nTPM]":"854.2","Tissue RNA - hippocampal formation [nTPM]":"1.7","Tissue RNA - hypothalamus [nTPM]":"2.3","Tissue RNA - kidney [nTPM]":"18.1","Tissue RNA - liver [nTPM]":"8.7","Tissue RNA - lung [nTPM]":"363.3","Tissue RNA - lymph node [nTPM]":"2.1","Tissue RNA - medulla oblongata [nTPM]":"3.3","Tissue RNA - midbrain [nTPM]":"2.3","Tissue RNA - ovary [nTPM]":"74.3","Tissue RNA - pancreas [nTPM]":"41.4","Tissue RNA - parathyroid gland [nTPM]":"1.7","Tissue RNA - pituitary gland [nTPM]":"9.0","Tissue RNA - placenta [nTPM]":"14.5","Tissue RNA - pons [nTPM]":"3.6","Tissue RNA - prostate [nTPM]":"277.8","Tissue RNA - rectum [nTPM]":"10.9","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"247.3","Tissue RNA - seminal vesicle [nTPM]":"6.3","Tissue RNA - skeletal muscle [nTPM]":"197.0","Tissue RNA - skin 1 [nTPM]":"488.6","Tissue RNA - small intestine [nTPM]":"248.4","Tissue RNA - smooth muscle [nTPM]":"4.0","Tissue RNA - spinal cord [nTPM]":"2.6","Tissue RNA - spleen [nTPM]":"28.6","Tissue RNA - stomach 1 [nTPM]":"263.8","Tissue RNA - testis [nTPM]":"51.8","Tissue RNA - thalamus [nTPM]":"2.9","Tissue RNA - thymus [nTPM]":"3.6","Tissue RNA - thyroid gland [nTPM]":"332.3","Tissue RNA - tongue [nTPM]":"26.9","Tissue RNA - tonsil [nTPM]":"0.8","Tissue RNA - urinary bladder [nTPM]":"848.3","Tissue RNA - vagina [nTPM]":"729.8","Tissue RNA - white matter [nTPM]":"5.8","Cell RNA - A-431 [nTPM]":"3.9","Cell RNA - A549 [nTPM]":"5.2","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"2.2","Cell RNA - ASC diff [nTPM]":"197.4","Cell RNA - ASC TERT1 [nTPM]":"26.2","Cell RNA - BEWO [nTPM]":"9.5","Cell RNA - BJ [nTPM]":"0.8","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.8","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"5.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"3.0","Cell RNA - HAP1 [nTPM]":"1.8","Cell RNA - HBEC3-KT [nTPM]":"0.5","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"5.7","Cell RNA - HEK 293 [nTPM]":"14.5","Cell RNA - HEL [nTPM]":"0.5","Cell RNA - HeLa [nTPM]":"12.3","Cell RNA - Hep G2 [nTPM]":"3.8","Cell RNA - HHSteC [nTPM]":"3.6","Cell RNA - HL-60 [nTPM]":"2.5","Cell RNA - HMC-1 [nTPM]":"4.9","Cell RNA - HSkMC [nTPM]":"8.7","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.8","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"4.5","Cell RNA - K-562 [nTPM]":"11.9","Cell RNA - Karpas-707 [nTPM]":"0.9","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"2.6","Cell RNA - MOLT-4 [nTPM]":"0.6","Cell RNA - NB-4 [nTPM]":"49.2","Cell RNA - NTERA-2 [nTPM]":"1.0","Cell RNA - OE19 [nTPM]":"4.5","Cell RNA - PC-3 [nTPM]":"16.1","Cell RNA - REH [nTPM]":"1.3","Cell RNA - RH-30 [nTPM]":"0.5","Cell RNA - RPMI-8226 [nTPM]":"5.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.3","Cell RNA - RT4 [nTPM]":"1.2","Cell RNA - SCLC-21H [nTPM]":"1.8","Cell RNA - SH-SY5Y [nTPM]":"1.8","Cell RNA - SiHa [nTPM]":"5.5","Cell RNA - SK-BR-3 [nTPM]":"1.9","Cell RNA - SK-MEL-30 [nTPM]":"0.5","Cell RNA - SuSa [nTPM]":"0.6","Cell RNA - T-47d [nTPM]":"7.5","Cell RNA - THP-1 [nTPM]":"342.2","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"5.1","Cell RNA - U-2197 [nTPM]":"2.9","Cell RNA - U-251 MG [nTPM]":"0.6","Cell RNA - U-266\/70 [nTPM]":"7.8","Cell RNA - U-266\/84 [nTPM]":"4.7","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"20.8","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"297.6","Blood RNA - classical monocyte [nTPM]":"41.2","Blood RNA - eosinophil [nTPM]":"127.8","Blood RNA - gdT-cell [nTPM]":"8.4","Blood RNA - intermediate monocyte [nTPM]":"55.5","Blood RNA - MAIT T-cell [nTPM]":"13.2","Blood RNA - memory B-cell [nTPM]":"5.7","Blood RNA - memory CD4 T-cell [nTPM]":"4.2","Blood RNA - memory CD8 T-cell [nTPM]":"10.2","Blood RNA - myeloid DC [nTPM]":"14.5","Blood RNA - naive B-cell [nTPM]":"1.4","Blood RNA - naive CD4 T-cell [nTPM]":"9.7","Blood RNA - naive CD8 T-cell [nTPM]":"9.7","Blood RNA - neutrophil [nTPM]":"112.0","Blood RNA - NK-cell [nTPM]":"1.3","Blood RNA - non-classical monocyte [nTPM]":"57.3","Blood RNA - plasmacytoid DC [nTPM]":"1.8","Blood RNA - T-reg [nTPM]":"4.7","Blood RNA - total PBMC [nTPM]":"37.8","Brain RNA - amygdala [nTPM]":"1.5","Brain RNA - basal ganglia [nTPM]":"1.6","Brain RNA - cerebellum [nTPM]":"1.2","Brain RNA - cerebral cortex [nTPM]":"2.4","Brain RNA - hippocampal formation [nTPM]":"1.7","Brain RNA - hypothalamus [nTPM]":"2.3","Brain RNA - medulla oblongata [nTPM]":"3.3","Brain RNA - midbrain [nTPM]":"2.3","Brain RNA - pons [nTPM]":"3.6","Brain RNA - spinal cord [nTPM]":"2.6","Brain RNA - thalamus [nTPM]":"2.9","Brain RNA - white matter [nTPM]":"5.8","Single Cell Type RNA - Adipocytes [nTPM]":"857.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"19.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"785.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"49.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Bipolar cells [nTPM]":"2.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"107.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"120.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"55.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"30.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"36.6","Single Cell Type RNA - dendritic cells [nTPM]":"40.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"33.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"7.7","Single Cell Type RNA - Early spermatids [nTPM]":"27.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"593.3","Single Cell Type RNA - Endothelial cells [nTPM]":"114.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"8.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"32.9","Single Cell Type RNA - Fibroblasts [nTPM]":"9365.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"113.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.9","Single Cell Type RNA - granulocytes [nTPM]":"17.1","Single Cell Type RNA - Granulosa cells [nTPM]":"0.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"30.4","Single Cell Type RNA - Hepatocytes [nTPM]":"2.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"272.4","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"424.7","Single Cell Type RNA - Langerhans cells [nTPM]":"1145.2","Single Cell Type RNA - Late spermatids [nTPM]":"89.6","Single Cell Type RNA - Leydig cells [nTPM]":"5032.4","Single Cell Type RNA - Macrophages [nTPM]":"442.5","Single Cell Type RNA - Melanocytes [nTPM]":"642.1","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"303.6","Single Cell Type RNA - Muller glia cells [nTPM]":"1.3","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.9","Single Cell Type RNA - Paneth cells [nTPM]":"64.8","Single Cell Type RNA - Peritubular cells [nTPM]":"283.2","Single Cell Type RNA - Plasma cells [nTPM]":"41.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"414.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"530.2","Single Cell Type RNA - Spermatocytes [nTPM]":"11.4","Single Cell Type RNA - Spermatogonia [nTPM]":"21.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"735.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"34.3","Single Cell Type RNA - T-cells [nTPM]":"82.8","Single Cell Type RNA - Theca cells [nTPM]":"1.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"21.0","Single Cell Type RNA - Urothelial cells [nTPM]":"233.2"},{"Gene":"CFI","Gene synonym":["C3b-INA","FI","IF","KAF"],"Ensembl":"ENSG00000205403","Gene description":"Complement factor I","Uniprot":["P05156"],"Chromosome":"4","Position":"109740694-109801999","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted secreted proteins"],"Biological process":["Complement pathway","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Age-related macular degeneration","Disease variant","Hemolytic uremic syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"liver":"1098.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"108.7","Hepatocytes":"592.5","Muller glia cells":"147.8","Proximal tubular cells":"223.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"90.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"106.1","Hep G2":"179.8","HSkMC":"67.4","RPTEC TERT1":"190.6"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001143","CAB016777","HPA024061"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB016777":null,"HPA001143":"AB_1078555","HPA024061":"AB_1847129"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.06e-4"},"Tissue RNA - adipose tissue [nTPM]":"45.1","Tissue RNA - adrenal gland [nTPM]":"50.2","Tissue RNA - amygdala [nTPM]":"8.1","Tissue RNA - appendix [nTPM]":"12.6","Tissue RNA - basal ganglia [nTPM]":"8.2","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"17.4","Tissue RNA - cerebellum [nTPM]":"7.7","Tissue RNA - cerebral cortex [nTPM]":"13.2","Tissue RNA - cervix [nTPM]":"36.8","Tissue RNA - choroid plexus [nTPM]":"10.4","Tissue RNA - colon [nTPM]":"7.4","Tissue RNA - duodenum [nTPM]":"38.0","Tissue RNA - endometrium 1 [nTPM]":"39.2","Tissue RNA - epididymis [nTPM]":"80.3","Tissue RNA - esophagus [nTPM]":"9.3","Tissue RNA - fallopian tube [nTPM]":"74.0","Tissue RNA - gallbladder [nTPM]":"73.0","Tissue RNA - heart muscle [nTPM]":"25.0","Tissue RNA - hippocampal formation [nTPM]":"8.3","Tissue RNA - hypothalamus [nTPM]":"9.6","Tissue RNA - kidney [nTPM]":"224.9","Tissue RNA - liver [nTPM]":"1098.8","Tissue RNA - lung [nTPM]":"50.7","Tissue RNA - lymph node [nTPM]":"8.9","Tissue RNA - medulla oblongata [nTPM]":"15.6","Tissue RNA - midbrain [nTPM]":"10.2","Tissue RNA - ovary [nTPM]":"32.1","Tissue RNA - pancreas [nTPM]":"26.0","Tissue RNA - parathyroid gland [nTPM]":"3.1","Tissue RNA - pituitary gland [nTPM]":"8.4","Tissue RNA - placenta [nTPM]":"24.1","Tissue RNA - pons [nTPM]":"10.7","Tissue RNA - prostate [nTPM]":"8.3","Tissue RNA - rectum [nTPM]":"6.4","Tissue RNA - retina [nTPM]":"53.0","Tissue RNA - salivary gland [nTPM]":"15.0","Tissue RNA - seminal vesicle [nTPM]":"26.7","Tissue RNA - skeletal muscle [nTPM]":"3.9","Tissue RNA - skin 1 [nTPM]":"2.7","Tissue RNA - small intestine [nTPM]":"22.3","Tissue RNA - smooth muscle [nTPM]":"24.3","Tissue RNA - spinal cord [nTPM]":"10.5","Tissue RNA - spleen [nTPM]":"33.1","Tissue RNA - stomach 1 [nTPM]":"14.4","Tissue RNA - testis [nTPM]":"8.8","Tissue RNA - thalamus [nTPM]":"9.2","Tissue RNA - thymus [nTPM]":"2.3","Tissue RNA - thyroid gland [nTPM]":"14.5","Tissue RNA - tongue [nTPM]":"4.6","Tissue RNA - tonsil [nTPM]":"7.5","Tissue RNA - urinary bladder [nTPM]":"34.1","Tissue RNA - vagina [nTPM]":"8.3","Tissue RNA - white matter [nTPM]":"10.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.6","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"1.5","Cell RNA - BJ hTERT+ [nTPM]":"1.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"106.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"32.9","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"34.8","Cell RNA - HEK 293 [nTPM]":"0.7","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"179.8","Cell RNA - HHSteC [nTPM]":"6.2","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"67.4","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"3.6","Cell RNA - HUVEC TERT2 [nTPM]":"4.8","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"190.6","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"1.6","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.6","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"18.8","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"8.1","Brain RNA - basal ganglia [nTPM]":"8.2","Brain RNA - cerebellum [nTPM]":"7.7","Brain RNA - cerebral cortex [nTPM]":"13.2","Brain RNA - hippocampal formation [nTPM]":"8.3","Brain RNA - hypothalamus [nTPM]":"9.6","Brain RNA - medulla oblongata [nTPM]":"15.6","Brain RNA - midbrain [nTPM]":"10.2","Brain RNA - pons [nTPM]":"10.7","Brain RNA - spinal cord [nTPM]":"10.5","Brain RNA - thalamus [nTPM]":"9.2","Brain RNA - white matter [nTPM]":"10.6","Single Cell Type RNA - Adipocytes [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"50.9","Single Cell Type RNA - Astrocytes [nTPM]":"3.6","Single Cell Type RNA - B-cells [nTPM]":"4.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"3.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"108.7","Single Cell Type RNA - Club cells [nTPM]":"36.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"64.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"31.3","Single Cell Type RNA - Ductal cells [nTPM]":"69.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"34.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"46.4","Single Cell Type RNA - Endothelial cells [nTPM]":"57.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"34.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"33.6","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"72.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"55.0","Single Cell Type RNA - Hepatocytes [nTPM]":"592.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.7","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"16.7","Single Cell Type RNA - Langerhans cells [nTPM]":"1.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"16.8","Single Cell Type RNA - Macrophages [nTPM]":"2.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"1.6","Single Cell Type RNA - Muller glia cells [nTPM]":"147.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"30.8","Single Cell Type RNA - Paneth cells [nTPM]":"2.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"223.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.4","Single Cell Type RNA - Spermatocytes [nTPM]":"1.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"3.4","Single Cell Type RNA - Theca cells [nTPM]":"18.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.1","Single Cell Type RNA - Urothelial cells [nTPM]":"12.6"},{"Gene":"CHAT","Gene synonym":[],"Ensembl":"ENSG00000070748","Gene description":"Choline O-acetyltransferase","Uniprot":["P28329"],"Chromosome":"10","Position":"49609095-49667942","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Neurotransmitter biosynthesis"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"brain":"13.0","placenta":"5.5"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"15","RNA cell line specific nTPM":{"NB-4":"20.9"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"20.6"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"7","RNA pig brain regional specific nTPM":{"basal ganglia":"6.5","pons":"7.0","spinal cord":"12.0"},"Antibody":["CAB002313","HPA048547","CAB079053"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002313":"AB_563661","CAB079053":null,"HPA048547":"AB_2680437"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.6","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"2.8","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"13.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"3.1","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"7.9","Tissue RNA - midbrain [nTPM]":"5.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"5.5","Tissue RNA - pons [nTPM]":"9.4","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.9","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"1.3","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"2.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.8","Cell RNA - NB-4 [nTPM]":"20.9","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.5","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"1.4","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.6","Brain RNA - basal ganglia [nTPM]":"2.8","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"13.0","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"3.1","Brain RNA - medulla oblongata [nTPM]":"7.9","Brain RNA - midbrain [nTPM]":"5.1","Brain RNA - pons [nTPM]":"9.4","Brain RNA - spinal cord [nTPM]":"1.3","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"2.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CHD1","Gene synonym":[],"Ensembl":"ENSG00000153922","Gene description":"Chromodomain helicase DNA binding protein 1","Uniprot":["O14646"],"Chromosome":"5","Position":"98853985-98929007","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"69.6"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022236"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Nucleoplasm","Nucleoli fibrillar center"],"Subcellular additional location":null,"Antibody RRID":{"HPA022236":"AB_2670915"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.25e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Tissue RNA - adipose tissue [nTPM]":"14.7","Tissue RNA - adrenal gland [nTPM]":"10.3","Tissue RNA - amygdala [nTPM]":"6.9","Tissue RNA - appendix [nTPM]":"17.8","Tissue RNA - basal ganglia [nTPM]":"7.3","Tissue RNA - bone marrow [nTPM]":"69.6","Tissue RNA - breast [nTPM]":"9.2","Tissue RNA - cerebellum [nTPM]":"17.9","Tissue RNA - cerebral cortex [nTPM]":"14.1","Tissue RNA - cervix [nTPM]":"8.0","Tissue RNA - choroid plexus [nTPM]":"8.8","Tissue RNA - colon [nTPM]":"10.5","Tissue RNA - duodenum [nTPM]":"9.8","Tissue RNA - endometrium 1 [nTPM]":"12.7","Tissue RNA - epididymis [nTPM]":"7.0","Tissue RNA - esophagus [nTPM]":"7.9","Tissue RNA - fallopian tube [nTPM]":"8.1","Tissue RNA - gallbladder [nTPM]":"15.0","Tissue RNA - heart muscle [nTPM]":"5.4","Tissue RNA - hippocampal formation [nTPM]":"6.1","Tissue RNA - hypothalamus [nTPM]":"8.3","Tissue RNA - kidney [nTPM]":"8.3","Tissue RNA - liver [nTPM]":"13.2","Tissue RNA - lung [nTPM]":"9.4","Tissue RNA - lymph node [nTPM]":"13.7","Tissue RNA - medulla oblongata [nTPM]":"9.7","Tissue RNA - midbrain [nTPM]":"7.7","Tissue RNA - ovary [nTPM]":"14.1","Tissue RNA - pancreas [nTPM]":"10.0","Tissue RNA - parathyroid gland [nTPM]":"9.4","Tissue RNA - pituitary gland [nTPM]":"4.8","Tissue RNA - placenta [nTPM]":"14.2","Tissue RNA - pons [nTPM]":"8.8","Tissue RNA - prostate [nTPM]":"8.2","Tissue RNA - rectum [nTPM]":"10.3","Tissue RNA - retina [nTPM]":"14.9","Tissue RNA - salivary gland [nTPM]":"5.4","Tissue RNA - seminal vesicle [nTPM]":"7.1","Tissue RNA - skeletal muscle [nTPM]":"9.7","Tissue RNA - skin 1 [nTPM]":"6.2","Tissue RNA - small intestine [nTPM]":"9.5","Tissue RNA - smooth muscle [nTPM]":"9.0","Tissue RNA - spinal cord [nTPM]":"7.4","Tissue RNA - spleen [nTPM]":"15.7","Tissue RNA - stomach 1 [nTPM]":"8.2","Tissue RNA - testis [nTPM]":"18.1","Tissue RNA - thalamus [nTPM]":"7.3","Tissue RNA - thymus [nTPM]":"49.6","Tissue RNA - thyroid gland [nTPM]":"8.8","Tissue RNA - tongue [nTPM]":"9.0","Tissue RNA - tonsil [nTPM]":"13.8","Tissue RNA - urinary bladder [nTPM]":"12.4","Tissue RNA - vagina [nTPM]":"5.9","Tissue RNA - white matter [nTPM]":"9.3","Cell RNA - A-431 [nTPM]":"23.0","Cell RNA - A549 [nTPM]":"20.7","Cell RNA - AF22 [nTPM]":"47.5","Cell RNA - AN3-CA [nTPM]":"32.3","Cell RNA - ASC diff [nTPM]":"15.7","Cell RNA - ASC TERT1 [nTPM]":"16.1","Cell RNA - BEWO [nTPM]":"41.3","Cell RNA - BJ [nTPM]":"23.2","Cell RNA - BJ hTERT+ [nTPM]":"15.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.8","Cell RNA - CACO-2 [nTPM]":"25.9","Cell RNA - CAPAN-2 [nTPM]":"17.3","Cell RNA - Daudi [nTPM]":"19.3","Cell RNA - EFO-21 [nTPM]":"22.0","Cell RNA - fHDF\/TERT166 [nTPM]":"13.5","Cell RNA - GAMG [nTPM]":"29.8","Cell RNA - HaCaT [nTPM]":"18.6","Cell RNA - HAP1 [nTPM]":"37.6","Cell RNA - HBEC3-KT [nTPM]":"25.6","Cell RNA - HBF TERT88 [nTPM]":"38.2","Cell RNA - HDLM-2 [nTPM]":"30.5","Cell RNA - HEK 293 [nTPM]":"28.2","Cell RNA - HEL [nTPM]":"34.2","Cell RNA - HeLa [nTPM]":"25.8","Cell RNA - Hep G2 [nTPM]":"19.8","Cell RNA - HHSteC [nTPM]":"17.3","Cell RNA - HL-60 [nTPM]":"33.3","Cell RNA - HMC-1 [nTPM]":"25.5","Cell RNA - HSkMC [nTPM]":"14.0","Cell RNA - hTCEpi [nTPM]":"10.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.0","Cell RNA - hTERT-HME1 [nTPM]":"32.2","Cell RNA - hTERT-RPE1 [nTPM]":"12.5","Cell RNA - HUVEC TERT2 [nTPM]":"22.6","Cell RNA - JURKAT [nTPM]":"62.0","Cell RNA - K-562 [nTPM]":"42.0","Cell RNA - Karpas-707 [nTPM]":"28.9","Cell RNA - LHCN-M2 [nTPM]":"18.7","Cell RNA - MCF7 [nTPM]":"18.5","Cell RNA - MOLT-4 [nTPM]":"66.4","Cell RNA - NB-4 [nTPM]":"14.4","Cell RNA - NTERA-2 [nTPM]":"32.0","Cell RNA - OE19 [nTPM]":"7.2","Cell RNA - PC-3 [nTPM]":"24.8","Cell RNA - REH [nTPM]":"55.7","Cell RNA - RH-30 [nTPM]":"33.2","Cell RNA - RPMI-8226 [nTPM]":"29.2","Cell RNA - RPTEC TERT1 [nTPM]":"16.0","Cell RNA - RT4 [nTPM]":"21.6","Cell RNA - SCLC-21H [nTPM]":"22.1","Cell RNA - SH-SY5Y [nTPM]":"18.9","Cell RNA - SiHa [nTPM]":"29.8","Cell RNA - SK-BR-3 [nTPM]":"15.4","Cell RNA - SK-MEL-30 [nTPM]":"37.9","Cell RNA - SuSa [nTPM]":"24.6","Cell RNA - T-47d [nTPM]":"15.0","Cell RNA - THP-1 [nTPM]":"22.6","Cell RNA - TIME [nTPM]":"25.7","Cell RNA - U-138 MG [nTPM]":"39.3","Cell RNA - U-2 OS [nTPM]":"21.2","Cell RNA - U-2197 [nTPM]":"24.9","Cell RNA - U-251 MG [nTPM]":"41.6","Cell RNA - U-266\/70 [nTPM]":"20.0","Cell RNA - U-266\/84 [nTPM]":"22.6","Cell RNA - U-698 [nTPM]":"40.0","Cell RNA - U-87 MG [nTPM]":"21.5","Cell RNA - U-937 [nTPM]":"32.6","Cell RNA - WM-115 [nTPM]":"24.2","Blood RNA - basophil [nTPM]":"13.1","Blood RNA - classical monocyte [nTPM]":"7.1","Blood RNA - eosinophil [nTPM]":"10.1","Blood RNA - gdT-cell [nTPM]":"5.4","Blood RNA - intermediate monocyte [nTPM]":"6.6","Blood RNA - MAIT T-cell [nTPM]":"6.9","Blood RNA - memory B-cell [nTPM]":"9.4","Blood RNA - memory CD4 T-cell [nTPM]":"5.1","Blood RNA - memory CD8 T-cell [nTPM]":"5.3","Blood RNA - myeloid DC [nTPM]":"6.5","Blood RNA - naive B-cell [nTPM]":"8.3","Blood RNA - naive CD4 T-cell [nTPM]":"7.0","Blood RNA - naive CD8 T-cell [nTPM]":"5.6","Blood RNA - neutrophil [nTPM]":"14.4","Blood RNA - NK-cell [nTPM]":"7.4","Blood RNA - non-classical monocyte [nTPM]":"6.8","Blood RNA - plasmacytoid DC [nTPM]":"4.7","Blood RNA - T-reg [nTPM]":"5.9","Blood RNA - total PBMC [nTPM]":"2.0","Brain RNA - amygdala [nTPM]":"6.9","Brain RNA - basal ganglia [nTPM]":"7.3","Brain RNA - cerebellum [nTPM]":"17.9","Brain RNA - cerebral cortex [nTPM]":"14.1","Brain RNA - hippocampal formation [nTPM]":"6.1","Brain RNA - hypothalamus [nTPM]":"8.3","Brain RNA - medulla oblongata [nTPM]":"9.7","Brain RNA - midbrain [nTPM]":"7.7","Brain RNA - pons [nTPM]":"8.8","Brain RNA - spinal cord [nTPM]":"7.4","Brain RNA - thalamus [nTPM]":"7.3","Brain RNA - white matter [nTPM]":"9.3","Single Cell Type RNA - Adipocytes [nTPM]":"87.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"72.2","Single Cell Type RNA - Astrocytes [nTPM]":"35.3","Single Cell Type RNA - B-cells [nTPM]":"145.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"155.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"99.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"26.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"115.5","Single Cell Type RNA - Bipolar cells [nTPM]":"39.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"85.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"56.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"29.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"57.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"43.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"53.9","Single Cell Type RNA - dendritic cells [nTPM]":"203.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"64.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"36.5","Single Cell Type RNA - Early spermatids [nTPM]":"101.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"84.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"114.3","Single Cell Type RNA - Endothelial cells [nTPM]":"79.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"31.8","Single Cell Type RNA - Erythroid cells [nTPM]":"40.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"50.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"32.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"38.4","Single Cell Type RNA - Fibroblasts [nTPM]":"104.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"50.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"107.3","Single Cell Type RNA - granulocytes [nTPM]":"89.2","Single Cell Type RNA - Granulosa cells [nTPM]":"45.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"40.0","Single Cell Type RNA - Hepatocytes [nTPM]":"30.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"35.6","Single Cell Type RNA - Horizontal cells [nTPM]":"33.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"59.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.2","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"65.8","Single Cell Type RNA - Langerhans cells [nTPM]":"145.9","Single Cell Type RNA - Late spermatids [nTPM]":"19.8","Single Cell Type RNA - Leydig cells [nTPM]":"32.3","Single Cell Type RNA - Macrophages [nTPM]":"169.7","Single Cell Type RNA - Melanocytes [nTPM]":"67.6","Single Cell Type RNA - Microglial cells [nTPM]":"90.9","Single Cell Type RNA - monocytes [nTPM]":"89.1","Single Cell Type RNA - Muller glia cells [nTPM]":"20.5","Single Cell Type RNA - NK-cells [nTPM]":"59.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"66.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"72.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"35.3","Single Cell Type RNA - Paneth cells [nTPM]":"51.4","Single Cell Type RNA - Peritubular cells [nTPM]":"19.2","Single Cell Type RNA - Plasma cells [nTPM]":"121.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"82.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"28.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"45.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"49.5","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"173.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"113.5","Single Cell Type RNA - Spermatocytes [nTPM]":"67.1","Single Cell Type RNA - Spermatogonia [nTPM]":"54.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"74.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"188.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"90.3","Single Cell Type RNA - T-cells [nTPM]":"148.2","Single Cell Type RNA - Theca cells [nTPM]":"49.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"39.4","Single Cell Type RNA - Urothelial cells [nTPM]":"75.4"},{"Gene":"CHD2","Gene synonym":["DKFZp547I1315","DKFZp686E01200","DKFZp781D1727","FLJ38614"],"Ensembl":"ENSG00000173575","Gene description":"Chromodomain helicase DNA binding protein 2","Uniprot":["O14647"],"Chromosome":"15","Position":"92900189-93027996","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Myogenesis","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060744","HPA060960"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA060744":"AB_2684353","HPA060960":"AB_2684398"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Tissue RNA - adipose tissue [nTPM]":"13.9","Tissue RNA - adrenal gland [nTPM]":"12.3","Tissue RNA - amygdala [nTPM]":"22.7","Tissue RNA - appendix [nTPM]":"20.7","Tissue RNA - basal ganglia [nTPM]":"25.5","Tissue RNA - bone marrow [nTPM]":"73.5","Tissue RNA - breast [nTPM]":"20.4","Tissue RNA - cerebellum [nTPM]":"42.0","Tissue RNA - cerebral cortex [nTPM]":"32.7","Tissue RNA - cervix [nTPM]":"15.7","Tissue RNA - choroid plexus [nTPM]":"32.0","Tissue RNA - colon [nTPM]":"15.2","Tissue RNA - duodenum [nTPM]":"14.8","Tissue RNA - endometrium 1 [nTPM]":"19.4","Tissue RNA - epididymis [nTPM]":"29.1","Tissue RNA - esophagus [nTPM]":"14.6","Tissue RNA - fallopian tube [nTPM]":"16.2","Tissue RNA - gallbladder [nTPM]":"15.6","Tissue RNA - heart muscle [nTPM]":"12.0","Tissue RNA - hippocampal formation [nTPM]":"21.3","Tissue RNA - hypothalamus [nTPM]":"24.7","Tissue RNA - kidney [nTPM]":"16.9","Tissue RNA - liver [nTPM]":"15.4","Tissue RNA - lung [nTPM]":"21.6","Tissue RNA - lymph node [nTPM]":"26.4","Tissue RNA - medulla oblongata [nTPM]":"29.0","Tissue RNA - midbrain [nTPM]":"23.3","Tissue RNA - ovary [nTPM]":"26.1","Tissue RNA - pancreas [nTPM]":"19.6","Tissue RNA - parathyroid gland [nTPM]":"18.2","Tissue RNA - pituitary gland [nTPM]":"16.6","Tissue RNA - placenta [nTPM]":"20.5","Tissue RNA - pons [nTPM]":"24.5","Tissue RNA - prostate [nTPM]":"20.4","Tissue RNA - rectum [nTPM]":"14.8","Tissue RNA - retina [nTPM]":"30.8","Tissue RNA - salivary gland [nTPM]":"21.2","Tissue RNA - seminal vesicle [nTPM]":"13.4","Tissue RNA - skeletal muscle [nTPM]":"17.4","Tissue RNA - skin 1 [nTPM]":"18.8","Tissue RNA - small intestine [nTPM]":"18.7","Tissue RNA - smooth muscle [nTPM]":"13.3","Tissue RNA - spinal cord [nTPM]":"22.1","Tissue RNA - spleen [nTPM]":"23.3","Tissue RNA - stomach 1 [nTPM]":"17.7","Tissue RNA - testis [nTPM]":"20.8","Tissue RNA - thalamus [nTPM]":"25.9","Tissue RNA - thymus [nTPM]":"27.0","Tissue RNA - thyroid gland [nTPM]":"26.3","Tissue RNA - tongue [nTPM]":"14.7","Tissue RNA - tonsil [nTPM]":"25.4","Tissue RNA - urinary bladder [nTPM]":"13.7","Tissue RNA - vagina [nTPM]":"16.1","Tissue RNA - white matter [nTPM]":"27.6","Cell RNA - A-431 [nTPM]":"21.3","Cell RNA - A549 [nTPM]":"11.6","Cell RNA - AF22 [nTPM]":"30.6","Cell RNA - AN3-CA [nTPM]":"13.6","Cell RNA - ASC diff [nTPM]":"17.9","Cell RNA - ASC TERT1 [nTPM]":"45.3","Cell RNA - BEWO [nTPM]":"23.0","Cell RNA - BJ [nTPM]":"19.4","Cell RNA - BJ hTERT+ [nTPM]":"20.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.1","Cell RNA - CACO-2 [nTPM]":"14.5","Cell RNA - CAPAN-2 [nTPM]":"27.4","Cell RNA - Daudi [nTPM]":"5.2","Cell RNA - EFO-21 [nTPM]":"16.1","Cell RNA - fHDF\/TERT166 [nTPM]":"17.3","Cell RNA - GAMG [nTPM]":"22.1","Cell RNA - HaCaT [nTPM]":"31.1","Cell RNA - HAP1 [nTPM]":"17.6","Cell RNA - HBEC3-KT [nTPM]":"19.5","Cell RNA - HBF TERT88 [nTPM]":"18.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"10.6","Cell RNA - HEL [nTPM]":"25.3","Cell RNA - HeLa [nTPM]":"26.1","Cell RNA - Hep G2 [nTPM]":"12.9","Cell RNA - HHSteC [nTPM]":"24.6","Cell RNA - HL-60 [nTPM]":"27.1","Cell RNA - HMC-1 [nTPM]":"19.0","Cell RNA - HSkMC [nTPM]":"28.7","Cell RNA - hTCEpi [nTPM]":"23.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.5","Cell RNA - hTERT-HME1 [nTPM]":"31.1","Cell RNA - hTERT-RPE1 [nTPM]":"26.8","Cell RNA - HUVEC TERT2 [nTPM]":"22.4","Cell RNA - JURKAT [nTPM]":"36.7","Cell RNA - K-562 [nTPM]":"26.8","Cell RNA - Karpas-707 [nTPM]":"57.1","Cell RNA - LHCN-M2 [nTPM]":"19.9","Cell RNA - MCF7 [nTPM]":"13.1","Cell RNA - MOLT-4 [nTPM]":"14.2","Cell RNA - NB-4 [nTPM]":"14.0","Cell RNA - NTERA-2 [nTPM]":"19.5","Cell RNA - OE19 [nTPM]":"10.5","Cell RNA - PC-3 [nTPM]":"12.6","Cell RNA - REH [nTPM]":"19.9","Cell RNA - RH-30 [nTPM]":"27.6","Cell RNA - RPMI-8226 [nTPM]":"28.4","Cell RNA - RPTEC TERT1 [nTPM]":"13.3","Cell RNA - RT4 [nTPM]":"28.5","Cell RNA - SCLC-21H [nTPM]":"16.8","Cell RNA - SH-SY5Y [nTPM]":"18.1","Cell RNA - SiHa [nTPM]":"34.2","Cell RNA - SK-BR-3 [nTPM]":"12.3","Cell RNA - SK-MEL-30 [nTPM]":"25.9","Cell RNA - SuSa [nTPM]":"30.6","Cell RNA - T-47d [nTPM]":"14.1","Cell RNA - THP-1 [nTPM]":"22.6","Cell RNA - TIME [nTPM]":"36.2","Cell RNA - U-138 MG [nTPM]":"10.7","Cell RNA - U-2 OS [nTPM]":"13.9","Cell RNA - U-2197 [nTPM]":"9.3","Cell RNA - U-251 MG [nTPM]":"12.8","Cell RNA - U-266\/70 [nTPM]":"53.4","Cell RNA - U-266\/84 [nTPM]":"23.2","Cell RNA - U-698 [nTPM]":"21.6","Cell RNA - U-87 MG [nTPM]":"15.9","Cell RNA - U-937 [nTPM]":"15.9","Cell RNA - WM-115 [nTPM]":"9.4","Blood RNA - basophil [nTPM]":"35.9","Blood RNA - classical monocyte [nTPM]":"10.8","Blood RNA - eosinophil [nTPM]":"27.7","Blood RNA - gdT-cell [nTPM]":"22.1","Blood RNA - intermediate monocyte [nTPM]":"6.6","Blood RNA - MAIT T-cell [nTPM]":"21.8","Blood RNA - memory B-cell [nTPM]":"48.7","Blood RNA - memory CD4 T-cell [nTPM]":"21.5","Blood RNA - memory CD8 T-cell [nTPM]":"20.5","Blood RNA - myeloid DC [nTPM]":"7.4","Blood RNA - naive B-cell [nTPM]":"39.6","Blood RNA - naive CD4 T-cell [nTPM]":"30.1","Blood RNA - naive CD8 T-cell [nTPM]":"22.1","Blood RNA - neutrophil [nTPM]":"53.7","Blood RNA - NK-cell [nTPM]":"20.6","Blood RNA - non-classical monocyte [nTPM]":"13.4","Blood RNA - plasmacytoid DC [nTPM]":"27.9","Blood RNA - T-reg [nTPM]":"24.9","Blood RNA - total PBMC [nTPM]":"10.9","Brain RNA - amygdala [nTPM]":"22.7","Brain RNA - basal ganglia [nTPM]":"25.5","Brain RNA - cerebellum [nTPM]":"42.0","Brain RNA - cerebral cortex [nTPM]":"32.7","Brain RNA - hippocampal formation [nTPM]":"21.3","Brain RNA - hypothalamus [nTPM]":"24.7","Brain RNA - medulla oblongata [nTPM]":"29.0","Brain RNA - midbrain [nTPM]":"23.3","Brain RNA - pons [nTPM]":"24.5","Brain RNA - spinal cord [nTPM]":"22.1","Brain RNA - thalamus [nTPM]":"25.9","Brain RNA - white matter [nTPM]":"27.6","Single Cell Type RNA - Adipocytes [nTPM]":"59.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"70.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"176.3","Single Cell Type RNA - Astrocytes [nTPM]":"182.2","Single Cell Type RNA - B-cells [nTPM]":"137.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"164.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"112.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"102.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"153.7","Single Cell Type RNA - Bipolar cells [nTPM]":"71.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"62.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"46.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"42.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"37.1","Single Cell Type RNA - Club cells [nTPM]":"137.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"46.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"91.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"30.7","Single Cell Type RNA - dendritic cells [nTPM]":"116.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"59.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"36.1","Single Cell Type RNA - Early spermatids [nTPM]":"56.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"96.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"61.7","Single Cell Type RNA - Endothelial cells [nTPM]":"58.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"59.3","Single Cell Type RNA - Erythroid cells [nTPM]":"65.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"161.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"38.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"28.5","Single Cell Type RNA - Fibroblasts [nTPM]":"64.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"96.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"189.8","Single Cell Type RNA - granulocytes [nTPM]":"99.3","Single Cell Type RNA - Granulosa cells [nTPM]":"70.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.0","Single Cell Type RNA - Hepatocytes [nTPM]":"34.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.8","Single Cell Type RNA - Horizontal cells [nTPM]":"57.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"146.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"54.9","Single Cell Type RNA - Ionocytes [nTPM]":"91.6","Single Cell Type RNA - Kupffer cells [nTPM]":"55.1","Single Cell Type RNA - Langerhans cells [nTPM]":"297.4","Single Cell Type RNA - Late spermatids [nTPM]":"39.2","Single Cell Type RNA - Leydig cells [nTPM]":"34.8","Single Cell Type RNA - Macrophages [nTPM]":"89.5","Single Cell Type RNA - Melanocytes [nTPM]":"96.0","Single Cell Type RNA - Microglial cells [nTPM]":"119.9","Single Cell Type RNA - monocytes [nTPM]":"50.7","Single Cell Type RNA - Muller glia cells [nTPM]":"34.2","Single Cell Type RNA - NK-cells [nTPM]":"48.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"140.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"155.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"64.2","Single Cell Type RNA - Paneth cells [nTPM]":"61.6","Single Cell Type RNA - Peritubular cells [nTPM]":"37.6","Single Cell Type RNA - Plasma cells [nTPM]":"133.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"110.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"39.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"93.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"82.2","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"52.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"64.4","Single Cell Type RNA - Spermatocytes [nTPM]":"15.3","Single Cell Type RNA - Spermatogonia [nTPM]":"14.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"125.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"180.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"60.5","Single Cell Type RNA - T-cells [nTPM]":"153.2","Single Cell Type RNA - Theca cells [nTPM]":"42.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"51.5","Single Cell Type RNA - Urothelial cells [nTPM]":"143.6"},{"Gene":"CHD3","Gene synonym":["Mi-2a","Mi2-ALPHA","ZFH"],"Ensembl":"ENSG00000170004","Gene description":"Chromodomain helicase DNA binding protein 3","Uniprot":["Q12873"],"Chromosome":"17","Position":"7884796-7912760","Protein class":["Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043368","HPA076524"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Centriolar satellite"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 51: Non-specific - Unknown function","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":["Centriolar satellite"],"Antibody RRID":{"HPA043368":"AB_2678448","HPA076524":"AB_2686804"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.43e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.68e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.36e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.90e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-3"},"Tissue RNA - adipose tissue [nTPM]":"28.2","Tissue RNA - adrenal gland [nTPM]":"29.3","Tissue RNA - amygdala [nTPM]":"19.9","Tissue RNA - appendix [nTPM]":"35.0","Tissue RNA - basal ganglia [nTPM]":"27.9","Tissue RNA - bone marrow [nTPM]":"42.7","Tissue RNA - breast [nTPM]":"28.4","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"39.9","Tissue RNA - cervix [nTPM]":"71.6","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"55.3","Tissue RNA - duodenum [nTPM]":"16.7","Tissue RNA - endometrium 1 [nTPM]":"63.9","Tissue RNA - epididymis [nTPM]":"31.2","Tissue RNA - esophagus [nTPM]":"35.1","Tissue RNA - fallopian tube [nTPM]":"56.8","Tissue RNA - gallbladder [nTPM]":"27.8","Tissue RNA - heart muscle [nTPM]":"21.2","Tissue RNA - hippocampal formation [nTPM]":"35.8","Tissue RNA - hypothalamus [nTPM]":"7.0","Tissue RNA - kidney [nTPM]":"38.3","Tissue RNA - liver [nTPM]":"5.7","Tissue RNA - lung [nTPM]":"32.4","Tissue RNA - lymph node [nTPM]":"41.3","Tissue RNA - medulla oblongata [nTPM]":"4.9","Tissue RNA - midbrain [nTPM]":"2.4","Tissue RNA - ovary [nTPM]":"60.0","Tissue RNA - pancreas [nTPM]":"34.8","Tissue RNA - parathyroid gland [nTPM]":"44.7","Tissue RNA - pituitary gland [nTPM]":"47.7","Tissue RNA - placenta [nTPM]":"16.6","Tissue RNA - pons [nTPM]":"1.1","Tissue RNA - prostate [nTPM]":"68.7","Tissue RNA - rectum [nTPM]":"22.1","Tissue RNA - retina [nTPM]":"19.0","Tissue RNA - salivary gland [nTPM]":"40.3","Tissue RNA - seminal vesicle [nTPM]":"38.0","Tissue RNA - skeletal muscle [nTPM]":"8.0","Tissue RNA - skin 1 [nTPM]":"32.7","Tissue RNA - small intestine [nTPM]":"34.6","Tissue RNA - smooth muscle [nTPM]":"45.0","Tissue RNA - spinal cord [nTPM]":"3.1","Tissue RNA - spleen [nTPM]":"31.5","Tissue RNA - stomach 1 [nTPM]":"36.3","Tissue RNA - testis [nTPM]":"20.9","Tissue RNA - thalamus [nTPM]":"8.0","Tissue RNA - thymus [nTPM]":"58.2","Tissue RNA - thyroid gland [nTPM]":"44.9","Tissue RNA - tongue [nTPM]":"9.1","Tissue RNA - tonsil [nTPM]":"36.7","Tissue RNA - urinary bladder [nTPM]":"41.2","Tissue RNA - vagina [nTPM]":"42.8","Tissue RNA - white matter [nTPM]":"21.4","Cell RNA - A-431 [nTPM]":"44.9","Cell RNA - A549 [nTPM]":"108.7","Cell RNA - AF22 [nTPM]":"61.6","Cell RNA - AN3-CA [nTPM]":"81.2","Cell RNA - ASC diff [nTPM]":"72.2","Cell RNA - ASC TERT1 [nTPM]":"60.9","Cell RNA - BEWO [nTPM]":"32.8","Cell RNA - BJ [nTPM]":"51.7","Cell RNA - BJ hTERT+ [nTPM]":"66.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"40.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"43.5","Cell RNA - CACO-2 [nTPM]":"21.1","Cell RNA - CAPAN-2 [nTPM]":"36.7","Cell RNA - Daudi [nTPM]":"122.8","Cell RNA - EFO-21 [nTPM]":"38.3","Cell RNA - fHDF\/TERT166 [nTPM]":"73.0","Cell RNA - GAMG [nTPM]":"34.0","Cell RNA - HaCaT [nTPM]":"59.6","Cell RNA - HAP1 [nTPM]":"117.7","Cell RNA - HBEC3-KT [nTPM]":"52.5","Cell RNA - HBF TERT88 [nTPM]":"53.0","Cell RNA - HDLM-2 [nTPM]":"65.5","Cell RNA - HEK 293 [nTPM]":"67.2","Cell RNA - HEL [nTPM]":"62.7","Cell RNA - HeLa [nTPM]":"148.5","Cell RNA - Hep G2 [nTPM]":"2.7","Cell RNA - HHSteC [nTPM]":"38.3","Cell RNA - HL-60 [nTPM]":"17.8","Cell RNA - HMC-1 [nTPM]":"112.1","Cell RNA - HSkMC [nTPM]":"79.2","Cell RNA - hTCEpi [nTPM]":"27.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"55.4","Cell RNA - hTERT-HME1 [nTPM]":"36.9","Cell RNA - hTERT-RPE1 [nTPM]":"108.7","Cell RNA - HUVEC TERT2 [nTPM]":"76.9","Cell RNA - JURKAT [nTPM]":"54.1","Cell RNA - K-562 [nTPM]":"41.5","Cell RNA - Karpas-707 [nTPM]":"2.0","Cell RNA - LHCN-M2 [nTPM]":"38.8","Cell RNA - MCF7 [nTPM]":"42.6","Cell RNA - MOLT-4 [nTPM]":"48.2","Cell RNA - NB-4 [nTPM]":"19.6","Cell RNA - NTERA-2 [nTPM]":"9.8","Cell RNA - OE19 [nTPM]":"45.3","Cell RNA - PC-3 [nTPM]":"40.3","Cell RNA - REH [nTPM]":"137.8","Cell RNA - RH-30 [nTPM]":"82.1","Cell RNA - RPMI-8226 [nTPM]":"19.3","Cell RNA - RPTEC TERT1 [nTPM]":"40.0","Cell RNA - RT4 [nTPM]":"107.7","Cell RNA - SCLC-21H [nTPM]":"41.9","Cell RNA - SH-SY5Y [nTPM]":"56.3","Cell RNA - SiHa [nTPM]":"126.4","Cell RNA - SK-BR-3 [nTPM]":"47.9","Cell RNA - SK-MEL-30 [nTPM]":"24.6","Cell RNA - SuSa [nTPM]":"16.9","Cell RNA - T-47d [nTPM]":"55.7","Cell RNA - THP-1 [nTPM]":"27.1","Cell RNA - TIME [nTPM]":"99.7","Cell RNA - U-138 MG [nTPM]":"89.4","Cell RNA - U-2 OS [nTPM]":"68.8","Cell RNA - U-2197 [nTPM]":"22.3","Cell RNA - U-251 MG [nTPM]":"72.5","Cell RNA - U-266\/70 [nTPM]":"8.8","Cell RNA - U-266\/84 [nTPM]":"1.6","Cell RNA - U-698 [nTPM]":"68.3","Cell RNA - U-87 MG [nTPM]":"46.1","Cell RNA - U-937 [nTPM]":"47.4","Cell RNA - WM-115 [nTPM]":"77.6","Blood RNA - basophil [nTPM]":"1.7","Blood RNA - classical monocyte [nTPM]":"2.6","Blood RNA - eosinophil [nTPM]":"3.3","Blood RNA - gdT-cell [nTPM]":"4.1","Blood RNA - intermediate monocyte [nTPM]":"1.4","Blood RNA - MAIT T-cell [nTPM]":"3.6","Blood RNA - memory B-cell [nTPM]":"1.1","Blood RNA - memory CD4 T-cell [nTPM]":"4.2","Blood RNA - memory CD8 T-cell [nTPM]":"4.0","Blood RNA - myeloid DC [nTPM]":"1.3","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"4.6","Blood RNA - naive CD8 T-cell [nTPM]":"3.1","Blood RNA - neutrophil [nTPM]":"2.8","Blood RNA - NK-cell [nTPM]":"3.2","Blood RNA - non-classical monocyte [nTPM]":"3.2","Blood RNA - plasmacytoid DC [nTPM]":"3.0","Blood RNA - T-reg [nTPM]":"2.5","Blood RNA - total PBMC [nTPM]":"2.5","Brain RNA - amygdala [nTPM]":"19.9","Brain RNA - basal ganglia [nTPM]":"27.9","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"39.9","Brain RNA - hippocampal formation [nTPM]":"35.8","Brain RNA - hypothalamus [nTPM]":"7.0","Brain RNA - medulla oblongata [nTPM]":"4.9","Brain RNA - midbrain [nTPM]":"2.4","Brain RNA - pons [nTPM]":"1.1","Brain RNA - spinal cord [nTPM]":"3.1","Brain RNA - thalamus [nTPM]":"8.0","Brain RNA - white matter [nTPM]":"21.4","Single Cell Type RNA - Adipocytes [nTPM]":"20.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"63.2","Single Cell Type RNA - Astrocytes [nTPM]":"10.4","Single Cell Type RNA - B-cells [nTPM]":"19.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"36.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"47.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"65.4","Single Cell Type RNA - Bipolar cells [nTPM]":"60.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"43.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"34.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"35.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"80.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.8","Single Cell Type RNA - dendritic cells [nTPM]":"57.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"39.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"22.9","Single Cell Type RNA - Early spermatids [nTPM]":"11.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"48.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"51.9","Single Cell Type RNA - Endothelial cells [nTPM]":"29.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"56.8","Single Cell Type RNA - Erythroid cells [nTPM]":"19.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"20.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.5","Single Cell Type RNA - Fibroblasts [nTPM]":"39.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"31.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"70.7","Single Cell Type RNA - granulocytes [nTPM]":"39.9","Single Cell Type RNA - Granulosa cells [nTPM]":"59.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.9","Single Cell Type RNA - Hepatocytes [nTPM]":"2.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.0","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.0","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"24.7","Single Cell Type RNA - Langerhans cells [nTPM]":"34.7","Single Cell Type RNA - Late spermatids [nTPM]":"18.5","Single Cell Type RNA - Leydig cells [nTPM]":"44.4","Single Cell Type RNA - Macrophages [nTPM]":"26.7","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"43.7","Single Cell Type RNA - Muller glia cells [nTPM]":"12.4","Single Cell Type RNA - NK-cells [nTPM]":"59.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.9","Single Cell Type RNA - Paneth cells [nTPM]":"10.8","Single Cell Type RNA - Peritubular cells [nTPM]":"57.2","Single Cell Type RNA - Plasma cells [nTPM]":"17.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"55.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"24.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.3","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"31.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"43.5","Single Cell Type RNA - Spermatocytes [nTPM]":"25.5","Single Cell Type RNA - Spermatogonia [nTPM]":"46.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"52.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.4","Single Cell Type RNA - T-cells [nTPM]":"62.9","Single Cell Type RNA - Theca cells [nTPM]":"52.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"30.3","Single Cell Type RNA - Urothelial cells [nTPM]":"60.3"},{"Gene":"CHD4","Gene synonym":["Mi-2b","Mi2-BETA"],"Ensembl":"ENSG00000111642","Gene description":"Chromodomain helicase DNA binding protein 4","Uniprot":["Q14839"],"Chromosome":"12","Position":"6570082-6614524","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012008"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA012008":"AB_1846633"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.03e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Tissue RNA - adipose tissue [nTPM]":"34.5","Tissue RNA - adrenal gland [nTPM]":"45.6","Tissue RNA - amygdala [nTPM]":"22.9","Tissue RNA - appendix [nTPM]":"38.6","Tissue RNA - basal ganglia [nTPM]":"30.7","Tissue RNA - bone marrow [nTPM]":"44.4","Tissue RNA - breast [nTPM]":"31.9","Tissue RNA - cerebellum [nTPM]":"24.6","Tissue RNA - cerebral cortex [nTPM]":"30.1","Tissue RNA - cervix [nTPM]":"39.4","Tissue RNA - choroid plexus [nTPM]":"20.6","Tissue RNA - colon [nTPM]":"45.7","Tissue RNA - duodenum [nTPM]":"26.5","Tissue RNA - endometrium 1 [nTPM]":"47.8","Tissue RNA - epididymis [nTPM]":"44.9","Tissue RNA - esophagus [nTPM]":"35.4","Tissue RNA - fallopian tube [nTPM]":"37.7","Tissue RNA - gallbladder [nTPM]":"31.1","Tissue RNA - heart muscle [nTPM]":"41.4","Tissue RNA - hippocampal formation [nTPM]":"19.7","Tissue RNA - hypothalamus [nTPM]":"26.1","Tissue RNA - kidney [nTPM]":"39.3","Tissue RNA - liver [nTPM]":"31.6","Tissue RNA - lung [nTPM]":"35.3","Tissue RNA - lymph node [nTPM]":"46.3","Tissue RNA - medulla oblongata [nTPM]":"27.3","Tissue RNA - midbrain [nTPM]":"29.2","Tissue RNA - ovary [nTPM]":"40.9","Tissue RNA - pancreas [nTPM]":"37.7","Tissue RNA - parathyroid gland [nTPM]":"58.3","Tissue RNA - pituitary gland [nTPM]":"33.5","Tissue RNA - placenta [nTPM]":"42.2","Tissue RNA - pons [nTPM]":"28.0","Tissue RNA - prostate [nTPM]":"28.4","Tissue RNA - rectum [nTPM]":"35.4","Tissue RNA - retina [nTPM]":"44.9","Tissue RNA - salivary gland [nTPM]":"33.8","Tissue RNA - seminal vesicle [nTPM]":"44.1","Tissue RNA - skeletal muscle [nTPM]":"50.0","Tissue RNA - skin 1 [nTPM]":"45.8","Tissue RNA - small intestine [nTPM]":"35.5","Tissue RNA - smooth muscle [nTPM]":"49.9","Tissue RNA - spinal cord [nTPM]":"22.6","Tissue RNA - spleen [nTPM]":"39.0","Tissue RNA - stomach 1 [nTPM]":"38.5","Tissue RNA - testis [nTPM]":"34.2","Tissue RNA - thalamus [nTPM]":"29.6","Tissue RNA - thymus [nTPM]":"90.7","Tissue RNA - thyroid gland [nTPM]":"54.6","Tissue RNA - tongue [nTPM]":"38.7","Tissue RNA - tonsil [nTPM]":"56.6","Tissue RNA - urinary bladder [nTPM]":"42.2","Tissue RNA - vagina [nTPM]":"34.4","Tissue RNA - white matter [nTPM]":"27.4","Cell RNA - A-431 [nTPM]":"86.7","Cell RNA - A549 [nTPM]":"79.7","Cell RNA - AF22 [nTPM]":"187.6","Cell RNA - AN3-CA [nTPM]":"72.1","Cell RNA - ASC diff [nTPM]":"76.6","Cell RNA - ASC TERT1 [nTPM]":"84.7","Cell RNA - BEWO [nTPM]":"110.4","Cell RNA - BJ [nTPM]":"92.9","Cell RNA - BJ hTERT+ [nTPM]":"93.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"102.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"93.5","Cell RNA - CACO-2 [nTPM]":"130.6","Cell RNA - CAPAN-2 [nTPM]":"66.6","Cell RNA - Daudi [nTPM]":"184.9","Cell RNA - EFO-21 [nTPM]":"36.0","Cell RNA - fHDF\/TERT166 [nTPM]":"107.5","Cell RNA - GAMG [nTPM]":"66.1","Cell RNA - HaCaT [nTPM]":"76.0","Cell RNA - HAP1 [nTPM]":"179.1","Cell RNA - HBEC3-KT [nTPM]":"104.5","Cell RNA - HBF TERT88 [nTPM]":"135.7","Cell RNA - HDLM-2 [nTPM]":"139.9","Cell RNA - HEK 293 [nTPM]":"92.7","Cell RNA - HEL [nTPM]":"258.5","Cell RNA - HeLa [nTPM]":"122.0","Cell RNA - Hep G2 [nTPM]":"83.3","Cell RNA - HHSteC [nTPM]":"67.1","Cell RNA - HL-60 [nTPM]":"207.2","Cell RNA - HMC-1 [nTPM]":"119.1","Cell RNA - HSkMC [nTPM]":"82.9","Cell RNA - hTCEpi [nTPM]":"51.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"99.1","Cell RNA - hTERT-HME1 [nTPM]":"68.7","Cell RNA - hTERT-RPE1 [nTPM]":"128.2","Cell RNA - HUVEC TERT2 [nTPM]":"122.2","Cell RNA - JURKAT [nTPM]":"101.6","Cell RNA - K-562 [nTPM]":"209.0","Cell RNA - Karpas-707 [nTPM]":"91.0","Cell RNA - LHCN-M2 [nTPM]":"98.7","Cell RNA - MCF7 [nTPM]":"111.8","Cell RNA - MOLT-4 [nTPM]":"196.6","Cell RNA - NB-4 [nTPM]":"67.8","Cell RNA - NTERA-2 [nTPM]":"184.7","Cell RNA - OE19 [nTPM]":"82.5","Cell RNA - PC-3 [nTPM]":"72.7","Cell RNA - REH [nTPM]":"166.4","Cell RNA - RH-30 [nTPM]":"114.9","Cell RNA - RPMI-8226 [nTPM]":"103.6","Cell RNA - RPTEC TERT1 [nTPM]":"64.2","Cell RNA - RT4 [nTPM]":"101.6","Cell RNA - SCLC-21H [nTPM]":"88.8","Cell RNA - SH-SY5Y [nTPM]":"114.6","Cell RNA - SiHa [nTPM]":"121.1","Cell RNA - SK-BR-3 [nTPM]":"136.0","Cell RNA - SK-MEL-30 [nTPM]":"92.9","Cell RNA - SuSa [nTPM]":"205.4","Cell RNA - T-47d [nTPM]":"61.3","Cell RNA - THP-1 [nTPM]":"121.3","Cell RNA - TIME [nTPM]":"114.4","Cell RNA - U-138 MG [nTPM]":"103.4","Cell RNA - U-2 OS [nTPM]":"217.4","Cell RNA - U-2197 [nTPM]":"76.3","Cell RNA - U-251 MG [nTPM]":"111.5","Cell RNA - U-266\/70 [nTPM]":"144.0","Cell RNA - U-266\/84 [nTPM]":"91.8","Cell RNA - U-698 [nTPM]":"230.2","Cell RNA - U-87 MG [nTPM]":"68.7","Cell RNA - U-937 [nTPM]":"125.8","Cell RNA - WM-115 [nTPM]":"79.5","Blood RNA - basophil [nTPM]":"12.3","Blood RNA - classical monocyte [nTPM]":"6.8","Blood RNA - eosinophil [nTPM]":"8.7","Blood RNA - gdT-cell [nTPM]":"9.3","Blood RNA - intermediate monocyte [nTPM]":"7.7","Blood RNA - MAIT T-cell [nTPM]":"9.6","Blood RNA - memory B-cell [nTPM]":"8.8","Blood RNA - memory CD4 T-cell [nTPM]":"8.4","Blood RNA - memory CD8 T-cell [nTPM]":"9.3","Blood RNA - myeloid DC [nTPM]":"6.9","Blood RNA - naive B-cell [nTPM]":"11.3","Blood RNA - naive CD4 T-cell [nTPM]":"10.6","Blood RNA - naive CD8 T-cell [nTPM]":"10.3","Blood RNA - neutrophil [nTPM]":"10.8","Blood RNA - NK-cell [nTPM]":"12.2","Blood RNA - non-classical monocyte [nTPM]":"8.0","Blood RNA - plasmacytoid DC [nTPM]":"14.4","Blood RNA - T-reg [nTPM]":"15.9","Blood RNA - total PBMC [nTPM]":"5.6","Brain RNA - amygdala [nTPM]":"22.9","Brain RNA - basal ganglia [nTPM]":"30.7","Brain RNA - cerebellum [nTPM]":"24.6","Brain RNA - cerebral cortex [nTPM]":"30.1","Brain RNA - hippocampal formation [nTPM]":"19.7","Brain RNA - hypothalamus [nTPM]":"26.1","Brain RNA - medulla oblongata [nTPM]":"27.3","Brain RNA - midbrain [nTPM]":"29.2","Brain RNA - pons [nTPM]":"28.0","Brain RNA - spinal cord [nTPM]":"22.6","Brain RNA - thalamus [nTPM]":"29.6","Brain RNA - white matter [nTPM]":"27.4","Single Cell Type RNA - Adipocytes [nTPM]":"68.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"119.7","Single Cell Type RNA - Astrocytes [nTPM]":"56.2","Single Cell Type RNA - B-cells [nTPM]":"82.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"68.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"47.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"42.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"76.2","Single Cell Type RNA - Bipolar cells [nTPM]":"109.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"77.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"61.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"132.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"58.6","Single Cell Type RNA - Club cells [nTPM]":"67.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"88.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"70.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"48.2","Single Cell Type RNA - dendritic cells [nTPM]":"106.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"58.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"84.6","Single Cell Type RNA - Early spermatids [nTPM]":"76.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"128.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"153.3","Single Cell Type RNA - Endothelial cells [nTPM]":"78.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"97.1","Single Cell Type RNA - Erythroid cells [nTPM]":"64.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"26.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"71.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"46.1","Single Cell Type RNA - Fibroblasts [nTPM]":"67.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"47.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"123.7","Single Cell Type RNA - granulocytes [nTPM]":"85.9","Single Cell Type RNA - Granulosa cells [nTPM]":"73.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"56.0","Single Cell Type RNA - Hepatocytes [nTPM]":"69.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"69.0","Single Cell Type RNA - Horizontal cells [nTPM]":"139.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"66.6","Single Cell Type RNA - Ionocytes [nTPM]":"54.9","Single Cell Type RNA - Kupffer cells [nTPM]":"51.9","Single Cell Type RNA - Langerhans cells [nTPM]":"78.3","Single Cell Type RNA - Late spermatids [nTPM]":"59.1","Single Cell Type RNA - Leydig cells [nTPM]":"65.9","Single Cell Type RNA - Macrophages [nTPM]":"68.9","Single Cell Type RNA - Melanocytes [nTPM]":"48.0","Single Cell Type RNA - Microglial cells [nTPM]":"25.3","Single Cell Type RNA - monocytes [nTPM]":"66.7","Single Cell Type RNA - Muller glia cells [nTPM]":"71.4","Single Cell Type RNA - NK-cells [nTPM]":"56.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"24.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"55.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"95.8","Single Cell Type RNA - Paneth cells [nTPM]":"36.4","Single Cell Type RNA - Peritubular cells [nTPM]":"74.4","Single Cell Type RNA - Plasma cells [nTPM]":"69.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"49.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"45.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"38.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"82.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"57.8","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"112.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"98.1","Single Cell Type RNA - Spermatocytes [nTPM]":"102.6","Single Cell Type RNA - Spermatogonia [nTPM]":"111.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"78.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"67.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"68.0","Single Cell Type RNA - T-cells [nTPM]":"85.1","Single Cell Type RNA - Theca cells [nTPM]":"83.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"72.1","Single Cell Type RNA - Urothelial cells [nTPM]":"47.4"},{"Gene":"CHD5","Gene synonym":[],"Ensembl":"ENSG00000116254","Gene description":"Chromodomain helicase DNA binding protein 5","Uniprot":["Q8TDI0"],"Chromosome":"1","Position":"6101787-6180321","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Differentiation","Neurogenesis","Spermatogenesis","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"59.0","pituitary gland":"57.3","testis":"31.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"84.3","Early spermatids":"217.8","Excitatory neurons":"80.4","Horizontal cells":"225.4","Inhibitory neurons":"56.2","Late spermatids":"113.2","Rod photoreceptor cells":"49.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"0.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"SCLC-21H":"12.9","U-2 OS":"5.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015809"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear speckles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 62: Horizontal cells - Visual perception","Subcellular main location":["Nucleoplasm","Nuclear speckles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA015809":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"4.1","Tissue RNA - amygdala [nTPM]":"31.8","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"40.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"59.0","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.1","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"34.3","Tissue RNA - hypothalamus [nTPM]":"13.6","Tissue RNA - kidney [nTPM]":"2.4","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"3.9","Tissue RNA - midbrain [nTPM]":"11.1","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"0.9","Tissue RNA - pituitary gland [nTPM]":"57.3","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"4.4","Tissue RNA - prostate [nTPM]":"0.9","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"7.9","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"2.2","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"1.0","Tissue RNA - testis [nTPM]":"31.8","Tissue RNA - thalamus [nTPM]":"10.2","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.7","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"31.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"0.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"2.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"1.2","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"1.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"12.9","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"2.3","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"5.7","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.6","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"31.8","Brain RNA - basal ganglia [nTPM]":"40.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"59.0","Brain RNA - hippocampal formation [nTPM]":"34.3","Brain RNA - hypothalamus [nTPM]":"13.6","Brain RNA - medulla oblongata [nTPM]":"3.9","Brain RNA - midbrain [nTPM]":"11.1","Brain RNA - pons [nTPM]":"4.4","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"10.2","Brain RNA - white matter [nTPM]":"31.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"84.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"217.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"80.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"225.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"56.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"113.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"49.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"4.5","Single Cell Type RNA - Spermatogonia [nTPM]":"17.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CHD6","Gene synonym":["CHD5","dJ620E11.1","FLJ22369","KIAA1335","RIGB"],"Ensembl":"ENSG00000124177","Gene description":"Chromodomain helicase DNA binding protein 6","Uniprot":["Q8TD26"],"Chromosome":"20","Position":"41402083-41618384","Protein class":["Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Helicase","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015543"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA015543":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.42e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.2","Tissue RNA - adrenal gland [nTPM]":"7.7","Tissue RNA - amygdala [nTPM]":"10.2","Tissue RNA - appendix [nTPM]":"6.9","Tissue RNA - basal ganglia [nTPM]":"11.4","Tissue RNA - bone marrow [nTPM]":"13.5","Tissue RNA - breast [nTPM]":"12.4","Tissue RNA - cerebellum [nTPM]":"17.5","Tissue RNA - cerebral cortex [nTPM]":"13.0","Tissue RNA - cervix [nTPM]":"9.5","Tissue RNA - choroid plexus [nTPM]":"6.0","Tissue RNA - colon [nTPM]":"7.1","Tissue RNA - duodenum [nTPM]":"4.0","Tissue RNA - endometrium 1 [nTPM]":"12.7","Tissue RNA - epididymis [nTPM]":"12.4","Tissue RNA - esophagus [nTPM]":"6.1","Tissue RNA - fallopian tube [nTPM]":"10.0","Tissue RNA - gallbladder [nTPM]":"7.2","Tissue RNA - heart muscle [nTPM]":"8.0","Tissue RNA - hippocampal formation [nTPM]":"8.5","Tissue RNA - hypothalamus [nTPM]":"13.1","Tissue RNA - kidney [nTPM]":"7.2","Tissue RNA - liver [nTPM]":"6.8","Tissue RNA - lung [nTPM]":"7.5","Tissue RNA - lymph node [nTPM]":"8.4","Tissue RNA - medulla oblongata [nTPM]":"11.7","Tissue RNA - midbrain [nTPM]":"10.9","Tissue RNA - ovary [nTPM]":"16.2","Tissue RNA - pancreas [nTPM]":"8.1","Tissue RNA - parathyroid gland [nTPM]":"16.2","Tissue RNA - pituitary gland [nTPM]":"7.9","Tissue RNA - placenta [nTPM]":"8.4","Tissue RNA - pons [nTPM]":"14.2","Tissue RNA - prostate [nTPM]":"12.2","Tissue RNA - rectum [nTPM]":"6.1","Tissue RNA - retina [nTPM]":"15.7","Tissue RNA - salivary gland [nTPM]":"8.4","Tissue RNA - seminal vesicle [nTPM]":"9.3","Tissue RNA - skeletal muscle [nTPM]":"5.5","Tissue RNA - skin 1 [nTPM]":"8.7","Tissue RNA - small intestine [nTPM]":"6.1","Tissue RNA - smooth muscle [nTPM]":"8.9","Tissue RNA - spinal cord [nTPM]":"7.3","Tissue RNA - spleen [nTPM]":"8.2","Tissue RNA - stomach 1 [nTPM]":"7.4","Tissue RNA - testis [nTPM]":"7.1","Tissue RNA - thalamus [nTPM]":"11.0","Tissue RNA - thymus [nTPM]":"17.2","Tissue RNA - thyroid gland [nTPM]":"13.6","Tissue RNA - tongue [nTPM]":"7.8","Tissue RNA - tonsil [nTPM]":"8.2","Tissue RNA - urinary bladder [nTPM]":"8.1","Tissue RNA - vagina [nTPM]":"8.8","Tissue RNA - white matter [nTPM]":"12.9","Cell RNA - A-431 [nTPM]":"8.4","Cell RNA - A549 [nTPM]":"9.8","Cell RNA - AF22 [nTPM]":"20.6","Cell RNA - AN3-CA [nTPM]":"9.2","Cell RNA - ASC diff [nTPM]":"11.5","Cell RNA - ASC TERT1 [nTPM]":"11.7","Cell RNA - BEWO [nTPM]":"13.3","Cell RNA - BJ [nTPM]":"7.2","Cell RNA - BJ hTERT+ [nTPM]":"14.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.2","Cell RNA - CACO-2 [nTPM]":"13.5","Cell RNA - CAPAN-2 [nTPM]":"6.7","Cell RNA - Daudi [nTPM]":"10.0","Cell RNA - EFO-21 [nTPM]":"12.7","Cell RNA - fHDF\/TERT166 [nTPM]":"12.4","Cell RNA - GAMG [nTPM]":"14.2","Cell RNA - HaCaT [nTPM]":"12.2","Cell RNA - HAP1 [nTPM]":"12.9","Cell RNA - HBEC3-KT [nTPM]":"12.4","Cell RNA - HBF TERT88 [nTPM]":"14.3","Cell RNA - HDLM-2 [nTPM]":"3.2","Cell RNA - HEK 293 [nTPM]":"6.3","Cell RNA - HEL [nTPM]":"13.7","Cell RNA - HeLa [nTPM]":"9.1","Cell RNA - Hep G2 [nTPM]":"13.2","Cell RNA - HHSteC [nTPM]":"6.5","Cell RNA - HL-60 [nTPM]":"10.9","Cell RNA - HMC-1 [nTPM]":"6.6","Cell RNA - HSkMC [nTPM]":"11.8","Cell RNA - hTCEpi [nTPM]":"11.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.2","Cell RNA - hTERT-HME1 [nTPM]":"10.1","Cell RNA - hTERT-RPE1 [nTPM]":"13.5","Cell RNA - HUVEC TERT2 [nTPM]":"11.0","Cell RNA - JURKAT [nTPM]":"13.7","Cell RNA - K-562 [nTPM]":"11.0","Cell RNA - Karpas-707 [nTPM]":"10.4","Cell RNA - LHCN-M2 [nTPM]":"9.9","Cell RNA - MCF7 [nTPM]":"23.3","Cell RNA - MOLT-4 [nTPM]":"17.3","Cell RNA - NB-4 [nTPM]":"11.8","Cell RNA - NTERA-2 [nTPM]":"6.8","Cell RNA - OE19 [nTPM]":"5.2","Cell RNA - PC-3 [nTPM]":"16.5","Cell RNA - REH [nTPM]":"13.2","Cell RNA - RH-30 [nTPM]":"24.2","Cell RNA - RPMI-8226 [nTPM]":"7.1","Cell RNA - RPTEC TERT1 [nTPM]":"7.9","Cell RNA - RT4 [nTPM]":"19.3","Cell RNA - SCLC-21H [nTPM]":"18.6","Cell RNA - SH-SY5Y [nTPM]":"12.8","Cell RNA - SiHa [nTPM]":"22.1","Cell RNA - SK-BR-3 [nTPM]":"5.8","Cell RNA - SK-MEL-30 [nTPM]":"14.2","Cell RNA - SuSa [nTPM]":"14.9","Cell RNA - T-47d [nTPM]":"9.9","Cell RNA - THP-1 [nTPM]":"8.1","Cell RNA - TIME [nTPM]":"12.7","Cell RNA - U-138 MG [nTPM]":"19.8","Cell RNA - U-2 OS [nTPM]":"9.6","Cell RNA - U-2197 [nTPM]":"10.0","Cell RNA - U-251 MG [nTPM]":"6.3","Cell RNA - U-266\/70 [nTPM]":"9.9","Cell RNA - U-266\/84 [nTPM]":"8.6","Cell RNA - U-698 [nTPM]":"12.8","Cell RNA - U-87 MG [nTPM]":"8.7","Cell RNA - U-937 [nTPM]":"5.2","Cell RNA - WM-115 [nTPM]":"6.2","Blood RNA - basophil [nTPM]":"20.2","Blood RNA - classical monocyte [nTPM]":"6.0","Blood RNA - eosinophil [nTPM]":"7.5","Blood RNA - gdT-cell [nTPM]":"8.1","Blood RNA - intermediate monocyte [nTPM]":"6.1","Blood RNA - MAIT T-cell [nTPM]":"8.2","Blood RNA - memory B-cell [nTPM]":"8.5","Blood RNA - memory CD4 T-cell [nTPM]":"7.0","Blood RNA - memory CD8 T-cell [nTPM]":"6.9","Blood RNA - myeloid DC [nTPM]":"5.2","Blood RNA - naive B-cell [nTPM]":"10.6","Blood RNA - naive CD4 T-cell [nTPM]":"9.4","Blood RNA - naive CD8 T-cell [nTPM]":"8.0","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"10.2","Blood RNA - non-classical monocyte [nTPM]":"10.0","Blood RNA - plasmacytoid DC [nTPM]":"11.4","Blood RNA - T-reg [nTPM]":"6.0","Blood RNA - total PBMC [nTPM]":"2.4","Brain RNA - amygdala [nTPM]":"10.2","Brain RNA - basal ganglia [nTPM]":"11.4","Brain RNA - cerebellum [nTPM]":"17.5","Brain RNA - cerebral cortex [nTPM]":"13.0","Brain RNA - hippocampal formation [nTPM]":"8.5","Brain RNA - hypothalamus [nTPM]":"13.1","Brain RNA - medulla oblongata [nTPM]":"11.7","Brain RNA - midbrain [nTPM]":"10.9","Brain RNA - pons [nTPM]":"14.2","Brain RNA - spinal cord [nTPM]":"7.3","Brain RNA - thalamus [nTPM]":"11.0","Brain RNA - white matter [nTPM]":"12.9","Single Cell Type RNA - Adipocytes [nTPM]":"42.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"30.8","Single Cell Type RNA - Astrocytes [nTPM]":"148.2","Single Cell Type RNA - B-cells [nTPM]":"42.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"38.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"37.0","Single Cell Type RNA - Bipolar cells [nTPM]":"140.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"39.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"34.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"56.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"34.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"93.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"34.2","Single Cell Type RNA - dendritic cells [nTPM]":"53.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"24.4","Single Cell Type RNA - Early spermatids [nTPM]":"14.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"50.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"65.3","Single Cell Type RNA - Endothelial cells [nTPM]":"36.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"60.6","Single Cell Type RNA - Erythroid cells [nTPM]":"19.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"143.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"28.2","Single Cell Type RNA - Fibroblasts [nTPM]":"33.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"76.0","Single Cell Type RNA - granulocytes [nTPM]":"21.5","Single Cell Type RNA - Granulosa cells [nTPM]":"65.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"34.2","Single Cell Type RNA - Hepatocytes [nTPM]":"21.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.5","Single Cell Type RNA - Horizontal cells [nTPM]":"151.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"179.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"35.9","Single Cell Type RNA - Ionocytes [nTPM]":"42.7","Single Cell Type RNA - Kupffer cells [nTPM]":"27.7","Single Cell Type RNA - Langerhans cells [nTPM]":"44.7","Single Cell Type RNA - Late spermatids [nTPM]":"20.3","Single Cell Type RNA - Leydig cells [nTPM]":"49.7","Single Cell Type RNA - Macrophages [nTPM]":"27.5","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"87.1","Single Cell Type RNA - monocytes [nTPM]":"40.8","Single Cell Type RNA - Muller glia cells [nTPM]":"62.2","Single Cell Type RNA - NK-cells [nTPM]":"39.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"182.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"160.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.4","Single Cell Type RNA - Paneth cells [nTPM]":"16.0","Single Cell Type RNA - Peritubular cells [nTPM]":"45.5","Single Cell Type RNA - Plasma cells [nTPM]":"32.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"35.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"133.8","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"71.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"44.4","Single Cell Type RNA - Spermatocytes [nTPM]":"20.6","Single Cell Type RNA - Spermatogonia [nTPM]":"61.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"32.7","Single Cell Type RNA - T-cells [nTPM]":"45.5","Single Cell Type RNA - Theca cells [nTPM]":"40.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.5","Single Cell Type RNA - Urothelial cells [nTPM]":"32.9"},{"Gene":"CHD7","Gene synonym":["CRG","FLJ20357","FLJ20361","KIAA1416"],"Ensembl":"ENSG00000171316","Gene description":"Chromodomain helicase DNA binding protein 7","Uniprot":["Q9P2D1"],"Chromosome":"8","Position":"60678740-60868028","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["rRNA processing","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Hypogonadotropic hypogonadism","Kallmann syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"71.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"241.8","Oligodendrocyte precursor cells":"298.6","Oligodendrocytes":"255.7","Rod photoreceptor cells":"198.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"15","RNA blood lineage specific nTPM":{"B-cells":"14.9","granulocytes":"17.6","T-cells":"6.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"51.5","SCLC-21H":"46.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053075"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA053075":"AB_2682035"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.34e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.6","Tissue RNA - adrenal gland [nTPM]":"1.9","Tissue RNA - amygdala [nTPM]":"10.3","Tissue RNA - appendix [nTPM]":"3.9","Tissue RNA - basal ganglia [nTPM]":"17.2","Tissue RNA - bone marrow [nTPM]":"22.1","Tissue RNA - breast [nTPM]":"3.5","Tissue RNA - cerebellum [nTPM]":"71.5","Tissue RNA - cerebral cortex [nTPM]":"11.0","Tissue RNA - cervix [nTPM]":"2.0","Tissue RNA - choroid plexus [nTPM]":"2.5","Tissue RNA - colon [nTPM]":"4.6","Tissue RNA - duodenum [nTPM]":"4.6","Tissue RNA - endometrium 1 [nTPM]":"2.2","Tissue RNA - epididymis [nTPM]":"2.2","Tissue RNA - esophagus [nTPM]":"4.9","Tissue RNA - fallopian tube [nTPM]":"2.3","Tissue RNA - gallbladder [nTPM]":"1.9","Tissue RNA - heart muscle [nTPM]":"3.8","Tissue RNA - hippocampal formation [nTPM]":"9.4","Tissue RNA - hypothalamus [nTPM]":"11.5","Tissue RNA - kidney [nTPM]":"3.8","Tissue RNA - liver [nTPM]":"3.2","Tissue RNA - lung [nTPM]":"4.6","Tissue RNA - lymph node [nTPM]":"5.8","Tissue RNA - medulla oblongata [nTPM]":"19.7","Tissue RNA - midbrain [nTPM]":"17.2","Tissue RNA - ovary [nTPM]":"1.0","Tissue RNA - pancreas [nTPM]":"4.4","Tissue RNA - parathyroid gland [nTPM]":"5.3","Tissue RNA - pituitary gland [nTPM]":"6.1","Tissue RNA - placenta [nTPM]":"4.3","Tissue RNA - pons [nTPM]":"18.8","Tissue RNA - prostate [nTPM]":"2.7","Tissue RNA - rectum [nTPM]":"4.0","Tissue RNA - retina [nTPM]":"23.7","Tissue RNA - salivary gland [nTPM]":"3.9","Tissue RNA - seminal vesicle [nTPM]":"1.7","Tissue RNA - skeletal muscle [nTPM]":"10.4","Tissue RNA - skin 1 [nTPM]":"5.2","Tissue RNA - small intestine [nTPM]":"6.4","Tissue RNA - smooth muscle [nTPM]":"1.7","Tissue RNA - spinal cord [nTPM]":"11.4","Tissue RNA - spleen [nTPM]":"5.6","Tissue RNA - stomach 1 [nTPM]":"3.5","Tissue RNA - testis [nTPM]":"2.9","Tissue RNA - thalamus [nTPM]":"15.6","Tissue RNA - thymus [nTPM]":"2.6","Tissue RNA - thyroid gland [nTPM]":"4.1","Tissue RNA - tongue [nTPM]":"4.1","Tissue RNA - tonsil [nTPM]":"5.7","Tissue RNA - urinary bladder [nTPM]":"3.4","Tissue RNA - vagina [nTPM]":"3.2","Tissue RNA - white matter [nTPM]":"17.7","Cell RNA - A-431 [nTPM]":"8.0","Cell RNA - A549 [nTPM]":"4.0","Cell RNA - AF22 [nTPM]":"51.5","Cell RNA - AN3-CA [nTPM]":"9.2","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"16.2","Cell RNA - BJ [nTPM]":"0.4","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.6","Cell RNA - CACO-2 [nTPM]":"10.0","Cell RNA - CAPAN-2 [nTPM]":"7.3","Cell RNA - Daudi [nTPM]":"15.5","Cell RNA - EFO-21 [nTPM]":"0.9","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"2.3","Cell RNA - HaCaT [nTPM]":"4.8","Cell RNA - HAP1 [nTPM]":"26.7","Cell RNA - HBEC3-KT [nTPM]":"7.9","Cell RNA - HBF TERT88 [nTPM]":"1.6","Cell RNA - HDLM-2 [nTPM]":"5.9","Cell RNA - HEK 293 [nTPM]":"14.3","Cell RNA - HEL [nTPM]":"36.5","Cell RNA - HeLa [nTPM]":"7.0","Cell RNA - Hep G2 [nTPM]":"13.2","Cell RNA - HHSteC [nTPM]":"2.1","Cell RNA - HL-60 [nTPM]":"11.1","Cell RNA - HMC-1 [nTPM]":"6.5","Cell RNA - HSkMC [nTPM]":"1.0","Cell RNA - hTCEpi [nTPM]":"5.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"8.5","Cell RNA - hTERT-RPE1 [nTPM]":"3.1","Cell RNA - HUVEC TERT2 [nTPM]":"7.7","Cell RNA - JURKAT [nTPM]":"12.5","Cell RNA - K-562 [nTPM]":"2.7","Cell RNA - Karpas-707 [nTPM]":"13.4","Cell RNA - LHCN-M2 [nTPM]":"1.2","Cell RNA - MCF7 [nTPM]":"8.3","Cell RNA - MOLT-4 [nTPM]":"17.5","Cell RNA - NB-4 [nTPM]":"12.7","Cell RNA - NTERA-2 [nTPM]":"35.4","Cell RNA - OE19 [nTPM]":"8.1","Cell RNA - PC-3 [nTPM]":"1.8","Cell RNA - REH [nTPM]":"36.0","Cell RNA - RH-30 [nTPM]":"12.1","Cell RNA - RPMI-8226 [nTPM]":"5.0","Cell RNA - RPTEC TERT1 [nTPM]":"4.1","Cell RNA - RT4 [nTPM]":"9.1","Cell RNA - SCLC-21H [nTPM]":"46.9","Cell RNA - SH-SY5Y [nTPM]":"23.2","Cell RNA - SiHa [nTPM]":"1.4","Cell RNA - SK-BR-3 [nTPM]":"5.9","Cell RNA - SK-MEL-30 [nTPM]":"14.9","Cell RNA - SuSa [nTPM]":"18.0","Cell RNA - T-47d [nTPM]":"10.5","Cell RNA - THP-1 [nTPM]":"10.5","Cell RNA - TIME [nTPM]":"9.0","Cell RNA - U-138 MG [nTPM]":"0.5","Cell RNA - U-2 OS [nTPM]":"8.3","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"4.3","Cell RNA - U-266\/70 [nTPM]":"14.2","Cell RNA - U-266\/84 [nTPM]":"8.7","Cell RNA - U-698 [nTPM]":"23.7","Cell RNA - U-87 MG [nTPM]":"3.0","Cell RNA - U-937 [nTPM]":"1.2","Cell RNA - WM-115 [nTPM]":"13.4","Blood RNA - basophil [nTPM]":"14.9","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"17.6","Blood RNA - gdT-cell [nTPM]":"3.2","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"4.1","Blood RNA - memory B-cell [nTPM]":"10.1","Blood RNA - memory CD4 T-cell [nTPM]":"3.6","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"14.9","Blood RNA - naive CD4 T-cell [nTPM]":"6.6","Blood RNA - naive CD8 T-cell [nTPM]":"2.4","Blood RNA - neutrophil [nTPM]":"9.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.8","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"10.3","Brain RNA - basal ganglia [nTPM]":"17.2","Brain RNA - cerebellum [nTPM]":"71.5","Brain RNA - cerebral cortex [nTPM]":"11.0","Brain RNA - hippocampal formation [nTPM]":"9.4","Brain RNA - hypothalamus [nTPM]":"11.5","Brain RNA - medulla oblongata [nTPM]":"19.7","Brain RNA - midbrain [nTPM]":"17.2","Brain RNA - pons [nTPM]":"18.8","Brain RNA - spinal cord [nTPM]":"11.4","Brain RNA - thalamus [nTPM]":"15.6","Brain RNA - white matter [nTPM]":"17.7","Single Cell Type RNA - Adipocytes [nTPM]":"35.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.5","Single Cell Type RNA - Astrocytes [nTPM]":"68.6","Single Cell Type RNA - B-cells [nTPM]":"64.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"35.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"36.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"35.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"20.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"241.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.2","Single Cell Type RNA - dendritic cells [nTPM]":"17.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"31.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"17.7","Single Cell Type RNA - Early spermatids [nTPM]":"15.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"34.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.1","Single Cell Type RNA - Endothelial cells [nTPM]":"40.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"87.3","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.6","Single Cell Type RNA - Fibroblasts [nTPM]":"6.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"28.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"37.6","Single Cell Type RNA - granulocytes [nTPM]":"41.0","Single Cell Type RNA - Granulosa cells [nTPM]":"39.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.4","Single Cell Type RNA - Hepatocytes [nTPM]":"12.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.9","Single Cell Type RNA - Horizontal cells [nTPM]":"70.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"39.9","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"10.8","Single Cell Type RNA - Langerhans cells [nTPM]":"10.4","Single Cell Type RNA - Late spermatids [nTPM]":"8.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"13.6","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"118.0","Single Cell Type RNA - monocytes [nTPM]":"13.9","Single Cell Type RNA - Muller glia cells [nTPM]":"121.3","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"298.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"255.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.9","Single Cell Type RNA - Paneth cells [nTPM]":"27.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"29.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"42.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"198.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"49.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.8","Single Cell Type RNA - Spermatocytes [nTPM]":"8.0","Single Cell Type RNA - Spermatogonia [nTPM]":"12.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"32.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.2","Single Cell Type RNA - T-cells [nTPM]":"21.4","Single Cell Type RNA - Theca cells [nTPM]":"3.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"34.1","Single Cell Type RNA - Urothelial cells [nTPM]":"35.8"},{"Gene":"CHD8","Gene synonym":["DUPLIN","HELSNF1","KIAA1564"],"Ensembl":"ENSG00000100888","Gene description":"Chromodomain helicase DNA binding protein 8","Uniprot":["Q9HCK8"],"Chromosome":"14","Position":"21385194-21456126","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation","Wnt signaling pathway"],"Molecular function":["Activator","Chromatin regulator","DNA-binding","Helicase","Hydrolase","Repressor"],"Disease involvement":["Autism","Autism spectrum disorder","Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052186","HPA076133"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA052186":"AB_2681754","HPA076133":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.94e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.35e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-3"},"Tissue RNA - adipose tissue [nTPM]":"12.5","Tissue RNA - adrenal gland [nTPM]":"11.9","Tissue RNA - amygdala [nTPM]":"11.2","Tissue RNA - appendix [nTPM]":"13.5","Tissue RNA - basal ganglia [nTPM]":"12.5","Tissue RNA - bone marrow [nTPM]":"35.3","Tissue RNA - breast [nTPM]":"14.8","Tissue RNA - cerebellum [nTPM]":"16.3","Tissue RNA - cerebral cortex [nTPM]":"13.2","Tissue RNA - cervix [nTPM]":"12.4","Tissue RNA - choroid plexus [nTPM]":"10.5","Tissue RNA - colon [nTPM]":"14.0","Tissue RNA - duodenum [nTPM]":"9.4","Tissue RNA - endometrium 1 [nTPM]":"14.8","Tissue RNA - epididymis [nTPM]":"11.1","Tissue RNA - esophagus [nTPM]":"14.9","Tissue RNA - fallopian tube [nTPM]":"12.9","Tissue RNA - gallbladder [nTPM]":"10.1","Tissue RNA - heart muscle [nTPM]":"12.0","Tissue RNA - hippocampal formation [nTPM]":"11.1","Tissue RNA - hypothalamus [nTPM]":"12.2","Tissue RNA - kidney [nTPM]":"11.7","Tissue RNA - liver [nTPM]":"9.6","Tissue RNA - lung [nTPM]":"13.7","Tissue RNA - lymph node [nTPM]":"18.0","Tissue RNA - medulla oblongata [nTPM]":"11.4","Tissue RNA - midbrain [nTPM]":"11.6","Tissue RNA - ovary [nTPM]":"17.1","Tissue RNA - pancreas [nTPM]":"13.6","Tissue RNA - parathyroid gland [nTPM]":"22.3","Tissue RNA - pituitary gland [nTPM]":"13.1","Tissue RNA - placenta [nTPM]":"11.7","Tissue RNA - pons [nTPM]":"11.1","Tissue RNA - prostate [nTPM]":"13.2","Tissue RNA - rectum [nTPM]":"12.3","Tissue RNA - retina [nTPM]":"14.8","Tissue RNA - salivary gland [nTPM]":"13.6","Tissue RNA - seminal vesicle [nTPM]":"12.1","Tissue RNA - skeletal muscle [nTPM]":"15.7","Tissue RNA - skin 1 [nTPM]":"22.3","Tissue RNA - small intestine [nTPM]":"14.7","Tissue RNA - smooth muscle [nTPM]":"14.8","Tissue RNA - spinal cord [nTPM]":"11.5","Tissue RNA - spleen [nTPM]":"15.8","Tissue RNA - stomach 1 [nTPM]":"14.2","Tissue RNA - testis [nTPM]":"12.9","Tissue RNA - thalamus [nTPM]":"12.5","Tissue RNA - thymus [nTPM]":"25.4","Tissue RNA - thyroid gland [nTPM]":"14.8","Tissue RNA - tongue [nTPM]":"12.7","Tissue RNA - tonsil [nTPM]":"17.5","Tissue RNA - urinary bladder [nTPM]":"12.8","Tissue RNA - vagina [nTPM]":"12.9","Tissue RNA - white matter [nTPM]":"13.6","Cell RNA - A-431 [nTPM]":"31.2","Cell RNA - A549 [nTPM]":"39.6","Cell RNA - AF22 [nTPM]":"43.6","Cell RNA - AN3-CA [nTPM]":"20.7","Cell RNA - ASC diff [nTPM]":"27.7","Cell RNA - ASC TERT1 [nTPM]":"23.6","Cell RNA - BEWO [nTPM]":"24.9","Cell RNA - BJ [nTPM]":"24.4","Cell RNA - BJ hTERT+ [nTPM]":"28.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"36.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"35.4","Cell RNA - CACO-2 [nTPM]":"35.0","Cell RNA - CAPAN-2 [nTPM]":"26.3","Cell RNA - Daudi [nTPM]":"51.4","Cell RNA - EFO-21 [nTPM]":"14.8","Cell RNA - fHDF\/TERT166 [nTPM]":"33.1","Cell RNA - GAMG [nTPM]":"28.4","Cell RNA - HaCaT [nTPM]":"37.2","Cell RNA - HAP1 [nTPM]":"54.9","Cell RNA - HBEC3-KT [nTPM]":"35.1","Cell RNA - HBF TERT88 [nTPM]":"46.0","Cell RNA - HDLM-2 [nTPM]":"39.3","Cell RNA - HEK 293 [nTPM]":"24.2","Cell RNA - HEL [nTPM]":"46.3","Cell RNA - HeLa [nTPM]":"27.6","Cell RNA - Hep G2 [nTPM]":"43.5","Cell RNA - HHSteC [nTPM]":"25.7","Cell RNA - HL-60 [nTPM]":"64.6","Cell RNA - HMC-1 [nTPM]":"40.4","Cell RNA - HSkMC [nTPM]":"32.8","Cell RNA - hTCEpi [nTPM]":"27.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"40.9","Cell RNA - hTERT-HME1 [nTPM]":"29.7","Cell RNA - hTERT-RPE1 [nTPM]":"28.6","Cell RNA - HUVEC TERT2 [nTPM]":"33.4","Cell RNA - JURKAT [nTPM]":"40.2","Cell RNA - K-562 [nTPM]":"32.4","Cell RNA - Karpas-707 [nTPM]":"26.7","Cell RNA - LHCN-M2 [nTPM]":"28.0","Cell RNA - MCF7 [nTPM]":"33.9","Cell RNA - MOLT-4 [nTPM]":"46.1","Cell RNA - NB-4 [nTPM]":"26.0","Cell RNA - NTERA-2 [nTPM]":"33.4","Cell RNA - OE19 [nTPM]":"30.9","Cell RNA - PC-3 [nTPM]":"34.3","Cell RNA - REH [nTPM]":"42.0","Cell RNA - RH-30 [nTPM]":"32.9","Cell RNA - RPMI-8226 [nTPM]":"17.4","Cell RNA - RPTEC TERT1 [nTPM]":"27.3","Cell RNA - RT4 [nTPM]":"57.9","Cell RNA - SCLC-21H [nTPM]":"30.9","Cell RNA - SH-SY5Y [nTPM]":"30.7","Cell RNA - SiHa [nTPM]":"37.5","Cell RNA - SK-BR-3 [nTPM]":"29.8","Cell RNA - SK-MEL-30 [nTPM]":"21.8","Cell RNA - SuSa [nTPM]":"39.7","Cell RNA - T-47d [nTPM]":"20.7","Cell RNA - THP-1 [nTPM]":"30.5","Cell RNA - TIME [nTPM]":"36.4","Cell RNA - U-138 MG [nTPM]":"29.2","Cell RNA - U-2 OS [nTPM]":"23.0","Cell RNA - U-2197 [nTPM]":"17.8","Cell RNA - U-251 MG [nTPM]":"29.1","Cell RNA - U-266\/70 [nTPM]":"30.3","Cell RNA - U-266\/84 [nTPM]":"38.4","Cell RNA - U-698 [nTPM]":"50.3","Cell RNA - U-87 MG [nTPM]":"12.1","Cell RNA - U-937 [nTPM]":"23.2","Cell RNA - WM-115 [nTPM]":"29.6","Blood RNA - basophil [nTPM]":"9.1","Blood RNA - classical monocyte [nTPM]":"3.8","Blood RNA - eosinophil [nTPM]":"9.8","Blood RNA - gdT-cell [nTPM]":"5.5","Blood RNA - intermediate monocyte [nTPM]":"3.8","Blood RNA - MAIT T-cell [nTPM]":"6.4","Blood RNA - memory B-cell [nTPM]":"4.2","Blood RNA - memory CD4 T-cell [nTPM]":"4.9","Blood RNA - memory CD8 T-cell [nTPM]":"5.6","Blood RNA - myeloid DC [nTPM]":"2.7","Blood RNA - naive B-cell [nTPM]":"11.2","Blood RNA - naive CD4 T-cell [nTPM]":"5.0","Blood RNA - naive CD8 T-cell [nTPM]":"4.4","Blood RNA - neutrophil [nTPM]":"7.9","Blood RNA - NK-cell [nTPM]":"7.8","Blood RNA - non-classical monocyte [nTPM]":"6.7","Blood RNA - plasmacytoid DC [nTPM]":"6.1","Blood RNA - T-reg [nTPM]":"4.7","Blood RNA - total PBMC [nTPM]":"2.7","Brain RNA - amygdala [nTPM]":"11.2","Brain RNA - basal ganglia [nTPM]":"12.5","Brain RNA - cerebellum [nTPM]":"16.3","Brain RNA - cerebral cortex [nTPM]":"13.2","Brain RNA - hippocampal formation [nTPM]":"11.1","Brain RNA - hypothalamus [nTPM]":"12.2","Brain RNA - medulla oblongata [nTPM]":"11.4","Brain RNA - midbrain [nTPM]":"11.6","Brain RNA - pons [nTPM]":"11.1","Brain RNA - spinal cord [nTPM]":"11.5","Brain RNA - thalamus [nTPM]":"12.5","Brain RNA - white matter [nTPM]":"13.6","Single Cell Type RNA - Adipocytes [nTPM]":"27.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"56.3","Single Cell Type RNA - Astrocytes [nTPM]":"27.4","Single Cell Type RNA - B-cells [nTPM]":"32.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.3","Single Cell Type RNA - Bipolar cells [nTPM]":"33.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"22.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"32.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.7","Single Cell Type RNA - dendritic cells [nTPM]":"40.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"21.8","Single Cell Type RNA - Early spermatids [nTPM]":"3.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"32.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"37.9","Single Cell Type RNA - Endothelial cells [nTPM]":"25.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"27.1","Single Cell Type RNA - Erythroid cells [nTPM]":"27.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"41.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.3","Single Cell Type RNA - Fibroblasts [nTPM]":"24.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"27.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"39.5","Single Cell Type RNA - granulocytes [nTPM]":"28.4","Single Cell Type RNA - Granulosa cells [nTPM]":"41.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.9","Single Cell Type RNA - Hepatocytes [nTPM]":"14.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.5","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"40.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.0","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"20.1","Single Cell Type RNA - Langerhans cells [nTPM]":"9.3","Single Cell Type RNA - Late spermatids [nTPM]":"4.1","Single Cell Type RNA - Leydig cells [nTPM]":"16.1","Single Cell Type RNA - Macrophages [nTPM]":"25.3","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"27.1","Single Cell Type RNA - Muller glia cells [nTPM]":"18.9","Single Cell Type RNA - NK-cells [nTPM]":"32.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"29.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"33.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"26.5","Single Cell Type RNA - Paneth cells [nTPM]":"13.9","Single Cell Type RNA - Peritubular cells [nTPM]":"17.7","Single Cell Type RNA - Plasma cells [nTPM]":"32.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"32.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.2","Single Cell Type RNA - Spermatocytes [nTPM]":"29.2","Single Cell Type RNA - Spermatogonia [nTPM]":"25.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"24.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.3","Single Cell Type RNA - T-cells [nTPM]":"31.4","Single Cell Type RNA - Theca cells [nTPM]":"34.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.8","Single Cell Type RNA - Urothelial cells [nTPM]":"12.7"},{"Gene":"CHEK2","Gene synonym":["bA444G7","CDS1","CHK2","HuCds1","PP1425","RAD53"],"Ensembl":"ENSG00000183765","Gene description":"Checkpoint kinase 2","Uniprot":["O96017"],"Chromosome":"22","Position":"28687743-28742422","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Cell cycle","Cell division","DNA damage","DNA repair","Mitosis","Transcription","Transcription regulation"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Li-Fraumeni syndrome","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatogonia":"31.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001878","CAB002030"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB002030":"AB_563660","HPA001878":"AB_1078514"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.62e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.80e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-3"},"Tissue RNA - adipose tissue [nTPM]":"4.5","Tissue RNA - adrenal gland [nTPM]":"6.2","Tissue RNA - amygdala [nTPM]":"2.4","Tissue RNA - appendix [nTPM]":"8.8","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"15.4","Tissue RNA - breast [nTPM]":"5.8","Tissue RNA - cerebellum [nTPM]":"2.4","Tissue RNA - cerebral cortex [nTPM]":"3.7","Tissue RNA - cervix [nTPM]":"5.0","Tissue RNA - choroid plexus [nTPM]":"2.8","Tissue RNA - colon [nTPM]":"8.8","Tissue RNA - duodenum [nTPM]":"6.3","Tissue RNA - endometrium 1 [nTPM]":"4.1","Tissue RNA - epididymis [nTPM]":"7.3","Tissue RNA - esophagus [nTPM]":"7.2","Tissue RNA - fallopian tube [nTPM]":"3.7","Tissue RNA - gallbladder [nTPM]":"4.7","Tissue RNA - heart muscle [nTPM]":"4.2","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"2.8","Tissue RNA - kidney [nTPM]":"4.5","Tissue RNA - liver [nTPM]":"6.3","Tissue RNA - lung [nTPM]":"4.4","Tissue RNA - lymph node [nTPM]":"12.1","Tissue RNA - medulla oblongata [nTPM]":"2.6","Tissue RNA - midbrain [nTPM]":"2.6","Tissue RNA - ovary [nTPM]":"8.2","Tissue RNA - pancreas [nTPM]":"2.3","Tissue RNA - parathyroid gland [nTPM]":"1.3","Tissue RNA - pituitary gland [nTPM]":"2.7","Tissue RNA - placenta [nTPM]":"7.8","Tissue RNA - pons [nTPM]":"2.8","Tissue RNA - prostate [nTPM]":"4.1","Tissue RNA - rectum [nTPM]":"10.9","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"3.2","Tissue RNA - seminal vesicle [nTPM]":"3.8","Tissue RNA - skeletal muscle [nTPM]":"1.3","Tissue RNA - skin 1 [nTPM]":"6.7","Tissue RNA - small intestine [nTPM]":"7.0","Tissue RNA - smooth muscle [nTPM]":"4.8","Tissue RNA - spinal cord [nTPM]":"2.6","Tissue RNA - spleen [nTPM]":"6.7","Tissue RNA - stomach 1 [nTPM]":"4.1","Tissue RNA - testis [nTPM]":"8.5","Tissue RNA - thalamus [nTPM]":"2.8","Tissue RNA - thymus [nTPM]":"9.4","Tissue RNA - thyroid gland [nTPM]":"3.3","Tissue RNA - tongue [nTPM]":"1.1","Tissue RNA - tonsil [nTPM]":"12.0","Tissue RNA - urinary bladder [nTPM]":"6.8","Tissue RNA - vagina [nTPM]":"5.0","Tissue RNA - white matter [nTPM]":"2.9","Cell RNA - A-431 [nTPM]":"30.7","Cell RNA - A549 [nTPM]":"9.7","Cell RNA - AF22 [nTPM]":"31.1","Cell RNA - AN3-CA [nTPM]":"32.4","Cell RNA - ASC diff [nTPM]":"10.1","Cell RNA - ASC TERT1 [nTPM]":"42.7","Cell RNA - BEWO [nTPM]":"18.7","Cell RNA - BJ [nTPM]":"15.2","Cell RNA - BJ hTERT+ [nTPM]":"19.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"27.8","Cell RNA - CACO-2 [nTPM]":"29.1","Cell RNA - CAPAN-2 [nTPM]":"21.8","Cell RNA - Daudi [nTPM]":"36.3","Cell RNA - EFO-21 [nTPM]":"13.0","Cell RNA - fHDF\/TERT166 [nTPM]":"11.5","Cell RNA - GAMG [nTPM]":"21.6","Cell RNA - HaCaT [nTPM]":"32.1","Cell RNA - HAP1 [nTPM]":"42.7","Cell RNA - HBEC3-KT [nTPM]":"29.0","Cell RNA - HBF TERT88 [nTPM]":"25.0","Cell RNA - HDLM-2 [nTPM]":"24.6","Cell RNA - HEK 293 [nTPM]":"31.2","Cell RNA - HEL [nTPM]":"45.3","Cell RNA - HeLa [nTPM]":"25.5","Cell RNA - Hep G2 [nTPM]":"46.2","Cell RNA - HHSteC [nTPM]":"9.4","Cell RNA - HL-60 [nTPM]":"33.4","Cell RNA - HMC-1 [nTPM]":"38.0","Cell RNA - HSkMC [nTPM]":"18.6","Cell RNA - hTCEpi [nTPM]":"13.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.0","Cell RNA - hTERT-HME1 [nTPM]":"23.0","Cell RNA - hTERT-RPE1 [nTPM]":"14.1","Cell RNA - HUVEC TERT2 [nTPM]":"25.4","Cell RNA - JURKAT [nTPM]":"29.4","Cell RNA - K-562 [nTPM]":"30.5","Cell RNA - Karpas-707 [nTPM]":"33.9","Cell RNA - LHCN-M2 [nTPM]":"19.8","Cell RNA - MCF7 [nTPM]":"39.2","Cell RNA - MOLT-4 [nTPM]":"24.6","Cell RNA - NB-4 [nTPM]":"61.5","Cell RNA - NTERA-2 [nTPM]":"40.6","Cell RNA - OE19 [nTPM]":"41.3","Cell RNA - PC-3 [nTPM]":"21.6","Cell RNA - REH [nTPM]":"52.6","Cell RNA - RH-30 [nTPM]":"18.2","Cell RNA - RPMI-8226 [nTPM]":"42.7","Cell RNA - RPTEC TERT1 [nTPM]":"17.1","Cell RNA - RT4 [nTPM]":"11.2","Cell RNA - SCLC-21H [nTPM]":"17.8","Cell RNA - SH-SY5Y [nTPM]":"9.7","Cell RNA - SiHa [nTPM]":"16.7","Cell RNA - SK-BR-3 [nTPM]":"31.4","Cell RNA - SK-MEL-30 [nTPM]":"17.4","Cell RNA - SuSa [nTPM]":"22.8","Cell RNA - T-47d [nTPM]":"22.6","Cell RNA - THP-1 [nTPM]":"32.2","Cell RNA - TIME [nTPM]":"7.8","Cell RNA - U-138 MG [nTPM]":"17.1","Cell RNA - U-2 OS [nTPM]":"19.4","Cell RNA - U-2197 [nTPM]":"14.3","Cell RNA - U-251 MG [nTPM]":"9.1","Cell RNA - U-266\/70 [nTPM]":"21.8","Cell RNA - U-266\/84 [nTPM]":"28.3","Cell RNA - U-698 [nTPM]":"65.4","Cell RNA - U-87 MG [nTPM]":"17.1","Cell RNA - U-937 [nTPM]":"34.9","Cell RNA - WM-115 [nTPM]":"21.0","Blood RNA - basophil [nTPM]":"9.9","Blood RNA - classical monocyte [nTPM]":"4.0","Blood RNA - eosinophil [nTPM]":"1.2","Blood RNA - gdT-cell [nTPM]":"1.1","Blood RNA - intermediate monocyte [nTPM]":"8.1","Blood RNA - MAIT T-cell [nTPM]":"2.4","Blood RNA - memory B-cell [nTPM]":"11.9","Blood RNA - memory CD4 T-cell [nTPM]":"2.1","Blood RNA - memory CD8 T-cell [nTPM]":"2.1","Blood RNA - myeloid DC [nTPM]":"8.2","Blood RNA - naive B-cell [nTPM]":"7.8","Blood RNA - naive CD4 T-cell [nTPM]":"4.0","Blood RNA - naive CD8 T-cell [nTPM]":"2.6","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"3.4","Blood RNA - non-classical monocyte [nTPM]":"4.1","Blood RNA - plasmacytoid DC [nTPM]":"6.1","Blood RNA - T-reg [nTPM]":"2.8","Blood RNA - total PBMC [nTPM]":"3.6","Brain RNA - amygdala [nTPM]":"2.4","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"2.4","Brain RNA - cerebral cortex [nTPM]":"3.7","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"2.8","Brain RNA - medulla oblongata [nTPM]":"2.6","Brain RNA - midbrain [nTPM]":"2.6","Brain RNA - pons [nTPM]":"2.8","Brain RNA - spinal cord [nTPM]":"2.6","Brain RNA - thalamus [nTPM]":"2.8","Brain RNA - white matter [nTPM]":"2.9","Single Cell Type RNA - Adipocytes [nTPM]":"2.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"2.9","Single Cell Type RNA - B-cells [nTPM]":"5.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"5.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.4","Single Cell Type RNA - dendritic cells [nTPM]":"1.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.8","Single Cell Type RNA - Early spermatids [nTPM]":"7.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.1","Single Cell Type RNA - Endothelial cells [nTPM]":"3.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"11.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.6","Single Cell Type RNA - Fibroblasts [nTPM]":"12.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.0","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"7.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"1.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.3","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"2.4","Single Cell Type RNA - Langerhans cells [nTPM]":"8.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"6.2","Single Cell Type RNA - Macrophages [nTPM]":"5.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"3.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.0","Single Cell Type RNA - Paneth cells [nTPM]":"4.7","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"11.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.0","Single Cell Type RNA - Spermatocytes [nTPM]":"6.7","Single Cell Type RNA - Spermatogonia [nTPM]":"31.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - T-cells [nTPM]":"3.3","Single Cell Type RNA - Theca cells [nTPM]":"5.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.0","Single Cell Type RNA - Urothelial cells [nTPM]":"4.5"},{"Gene":"CHKB","Gene synonym":["CHETK","CHKL"],"Ensembl":"ENSG00000100288","Gene description":"Choline kinase beta","Uniprot":["Q9Y259"],"Chromosome":"22","Position":"50578959-50601455","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Congenital muscular dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"monocytes":"48.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HHSteC":"19.1","RPMI-8226":"19.8"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018797"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 3: Monocytes - Immune response regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA018797":"AB_1846666"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.66e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.56e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-3"},"Tissue RNA - adipose tissue [nTPM]":"14.1","Tissue RNA - adrenal gland [nTPM]":"13.0","Tissue RNA - amygdala [nTPM]":"10.3","Tissue RNA - appendix [nTPM]":"0.7","Tissue RNA - basal ganglia [nTPM]":"10.3","Tissue RNA - bone marrow [nTPM]":"12.1","Tissue RNA - breast [nTPM]":"13.4","Tissue RNA - cerebellum [nTPM]":"10.5","Tissue RNA - cerebral cortex [nTPM]":"16.8","Tissue RNA - cervix [nTPM]":"10.6","Tissue RNA - choroid plexus [nTPM]":"12.2","Tissue RNA - colon [nTPM]":"10.5","Tissue RNA - duodenum [nTPM]":"3.3","Tissue RNA - endometrium 1 [nTPM]":"9.5","Tissue RNA - epididymis [nTPM]":"12.0","Tissue RNA - esophagus [nTPM]":"11.1","Tissue RNA - fallopian tube [nTPM]":"12.0","Tissue RNA - gallbladder [nTPM]":"1.5","Tissue RNA - heart muscle [nTPM]":"11.5","Tissue RNA - hippocampal formation [nTPM]":"10.1","Tissue RNA - hypothalamus [nTPM]":"10.8","Tissue RNA - kidney [nTPM]":"13.2","Tissue RNA - liver [nTPM]":"9.4","Tissue RNA - lung [nTPM]":"13.3","Tissue RNA - lymph node [nTPM]":"4.3","Tissue RNA - medulla oblongata [nTPM]":"10.5","Tissue RNA - midbrain [nTPM]":"11.0","Tissue RNA - ovary [nTPM]":"8.6","Tissue RNA - pancreas [nTPM]":"7.7","Tissue RNA - parathyroid gland [nTPM]":"17.7","Tissue RNA - pituitary gland [nTPM]":"14.3","Tissue RNA - placenta [nTPM]":"7.2","Tissue RNA - pons [nTPM]":"10.6","Tissue RNA - prostate [nTPM]":"12.0","Tissue RNA - rectum [nTPM]":"4.8","Tissue RNA - retina [nTPM]":"1.6","Tissue RNA - salivary gland [nTPM]":"11.9","Tissue RNA - seminal vesicle [nTPM]":"7.2","Tissue RNA - skeletal muscle [nTPM]":"8.3","Tissue RNA - skin 1 [nTPM]":"11.6","Tissue RNA - small intestine [nTPM]":"10.7","Tissue RNA - smooth muscle [nTPM]":"5.3","Tissue RNA - spinal cord [nTPM]":"10.7","Tissue RNA - spleen [nTPM]":"18.1","Tissue RNA - stomach 1 [nTPM]":"11.6","Tissue RNA - testis [nTPM]":"14.5","Tissue RNA - thalamus [nTPM]":"11.0","Tissue RNA - thymus [nTPM]":"9.2","Tissue RNA - thyroid gland [nTPM]":"12.6","Tissue RNA - tongue [nTPM]":"11.7","Tissue RNA - tonsil [nTPM]":"9.8","Tissue RNA - urinary bladder [nTPM]":"11.7","Tissue RNA - vagina [nTPM]":"11.1","Tissue RNA - white matter [nTPM]":"10.8","Cell RNA - A-431 [nTPM]":"4.2","Cell RNA - A549 [nTPM]":"1.3","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"1.6","Cell RNA - ASC diff [nTPM]":"6.7","Cell RNA - ASC TERT1 [nTPM]":"5.9","Cell RNA - BEWO [nTPM]":"10.8","Cell RNA - BJ [nTPM]":"7.3","Cell RNA - BJ hTERT+ [nTPM]":"16.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.1","Cell RNA - CACO-2 [nTPM]":"1.4","Cell RNA - CAPAN-2 [nTPM]":"2.1","Cell RNA - Daudi [nTPM]":"2.1","Cell RNA - EFO-21 [nTPM]":"4.2","Cell RNA - fHDF\/TERT166 [nTPM]":"3.8","Cell RNA - GAMG [nTPM]":"2.4","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"1.5","Cell RNA - HBEC3-KT [nTPM]":"2.0","Cell RNA - HBF TERT88 [nTPM]":"1.0","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"5.4","Cell RNA - HEL [nTPM]":"3.1","Cell RNA - HeLa [nTPM]":"2.2","Cell RNA - Hep G2 [nTPM]":"2.3","Cell RNA - HHSteC [nTPM]":"19.1","Cell RNA - HL-60 [nTPM]":"2.5","Cell RNA - HMC-1 [nTPM]":"4.8","Cell RNA - HSkMC [nTPM]":"2.0","Cell RNA - hTCEpi [nTPM]":"6.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.6","Cell RNA - hTERT-HME1 [nTPM]":"8.1","Cell RNA - hTERT-RPE1 [nTPM]":"4.5","Cell RNA - HUVEC TERT2 [nTPM]":"17.1","Cell RNA - JURKAT [nTPM]":"5.5","Cell RNA - K-562 [nTPM]":"1.8","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"12.4","Cell RNA - MCF7 [nTPM]":"5.3","Cell RNA - MOLT-4 [nTPM]":"2.0","Cell RNA - NB-4 [nTPM]":"8.6","Cell RNA - NTERA-2 [nTPM]":"0.7","Cell RNA - OE19 [nTPM]":"7.0","Cell RNA - PC-3 [nTPM]":"1.9","Cell RNA - REH [nTPM]":"3.5","Cell RNA - RH-30 [nTPM]":"1.8","Cell RNA - RPMI-8226 [nTPM]":"19.8","Cell RNA - RPTEC TERT1 [nTPM]":"11.5","Cell RNA - RT4 [nTPM]":"2.0","Cell RNA - SCLC-21H [nTPM]":"2.0","Cell RNA - SH-SY5Y [nTPM]":"3.2","Cell RNA - SiHa [nTPM]":"3.0","Cell RNA - SK-BR-3 [nTPM]":"7.3","Cell RNA - SK-MEL-30 [nTPM]":"5.9","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"1.1","Cell RNA - THP-1 [nTPM]":"2.8","Cell RNA - TIME [nTPM]":"6.9","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.7","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"2.2","Cell RNA - U-266\/70 [nTPM]":"7.4","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"3.0","Cell RNA - U-87 MG [nTPM]":"2.3","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"3.4","Blood RNA - basophil [nTPM]":"12.0","Blood RNA - classical monocyte [nTPM]":"39.5","Blood RNA - eosinophil [nTPM]":"27.0","Blood RNA - gdT-cell [nTPM]":"26.4","Blood RNA - intermediate monocyte [nTPM]":"38.4","Blood RNA - MAIT T-cell [nTPM]":"25.7","Blood RNA - memory B-cell [nTPM]":"24.0","Blood RNA - memory CD4 T-cell [nTPM]":"24.2","Blood RNA - memory CD8 T-cell [nTPM]":"27.6","Blood RNA - myeloid DC [nTPM]":"35.7","Blood RNA - naive B-cell [nTPM]":"23.6","Blood RNA - naive CD4 T-cell [nTPM]":"22.6","Blood RNA - naive CD8 T-cell [nTPM]":"20.8","Blood RNA - neutrophil [nTPM]":"9.6","Blood RNA - NK-cell [nTPM]":"37.0","Blood RNA - non-classical monocyte [nTPM]":"26.1","Blood RNA - plasmacytoid DC [nTPM]":"34.1","Blood RNA - T-reg [nTPM]":"33.4","Blood RNA - total PBMC [nTPM]":"32.6","Brain RNA - amygdala [nTPM]":"10.3","Brain RNA - basal ganglia [nTPM]":"10.3","Brain RNA - cerebellum [nTPM]":"10.5","Brain RNA - cerebral cortex [nTPM]":"16.8","Brain RNA - hippocampal formation [nTPM]":"10.1","Brain RNA - hypothalamus [nTPM]":"10.8","Brain RNA - medulla oblongata [nTPM]":"10.5","Brain RNA - midbrain [nTPM]":"11.0","Brain RNA - pons [nTPM]":"10.6","Brain RNA - spinal cord [nTPM]":"10.7","Brain RNA - thalamus [nTPM]":"11.0","Brain RNA - white matter [nTPM]":"10.8","Single Cell Type RNA - Adipocytes [nTPM]":"16.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"28.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"13.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"4.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"12.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.8","Single Cell Type RNA - dendritic cells [nTPM]":"14.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"30.6","Single Cell Type RNA - Early spermatids [nTPM]":"11.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.4","Single Cell Type RNA - Endothelial cells [nTPM]":"8.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.7","Single Cell Type RNA - Erythroid cells [nTPM]":"9.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.1","Single Cell Type RNA - Fibroblasts [nTPM]":"8.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.3","Single Cell Type RNA - granulocytes [nTPM]":"19.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.4","Single Cell Type RNA - Hepatocytes [nTPM]":"5.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.6","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.3","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"16.6","Single Cell Type RNA - Langerhans cells [nTPM]":"9.2","Single Cell Type RNA - Late spermatids [nTPM]":"30.5","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"10.0","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"48.4","Single Cell Type RNA - Muller glia cells [nTPM]":"3.3","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"23.5","Single Cell Type RNA - Paneth cells [nTPM]":"24.2","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"14.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"29.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.8","Single Cell Type RNA - Spermatocytes [nTPM]":"12.6","Single Cell Type RNA - Spermatogonia [nTPM]":"10.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.5","Single Cell Type RNA - T-cells [nTPM]":"11.2","Single Cell Type RNA - Theca cells [nTPM]":"2.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.3","Single Cell Type RNA - Urothelial cells [nTPM]":"2.2"},{"Gene":"CHP1","Gene synonym":["CHP","p22","p24","Sid470p","SLC9A1BP"],"Ensembl":"ENSG00000187446","Gene description":"Calcineurin like EF-hand protein 1","Uniprot":["Q99653"],"Chromosome":"15","Position":"41230839-41281887","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":["Protein kinase inhibitor"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"434.4","Distal tubular cells":"389.4","Hepatocytes":"353.6","Proximal enterocytes":"425.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006616"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA006616":"AB_1857461"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.63e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.07e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.79e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Tissue RNA - adipose tissue [nTPM]":"66.9","Tissue RNA - adrenal gland [nTPM]":"55.3","Tissue RNA - amygdala [nTPM]":"22.1","Tissue RNA - appendix [nTPM]":"28.0","Tissue RNA - basal ganglia [nTPM]":"24.4","Tissue RNA - bone marrow [nTPM]":"58.4","Tissue RNA - breast [nTPM]":"32.8","Tissue RNA - cerebellum [nTPM]":"26.0","Tissue RNA - cerebral cortex [nTPM]":"26.5","Tissue RNA - cervix [nTPM]":"34.0","Tissue RNA - choroid plexus [nTPM]":"24.7","Tissue RNA - colon [nTPM]":"113.8","Tissue RNA - duodenum [nTPM]":"85.4","Tissue RNA - endometrium 1 [nTPM]":"21.8","Tissue RNA - epididymis [nTPM]":"34.1","Tissue RNA - esophagus [nTPM]":"74.5","Tissue RNA - fallopian tube [nTPM]":"20.8","Tissue RNA - gallbladder [nTPM]":"48.1","Tissue RNA - heart muscle [nTPM]":"53.2","Tissue RNA - hippocampal formation [nTPM]":"30.3","Tissue RNA - hypothalamus [nTPM]":"32.9","Tissue RNA - kidney [nTPM]":"76.1","Tissue RNA - liver [nTPM]":"185.1","Tissue RNA - lung [nTPM]":"52.7","Tissue RNA - lymph node [nTPM]":"18.6","Tissue RNA - medulla oblongata [nTPM]":"32.9","Tissue RNA - midbrain [nTPM]":"31.0","Tissue RNA - ovary [nTPM]":"19.1","Tissue RNA - pancreas [nTPM]":"42.2","Tissue RNA - parathyroid gland [nTPM]":"54.1","Tissue RNA - pituitary gland [nTPM]":"21.6","Tissue RNA - placenta [nTPM]":"26.3","Tissue RNA - pons [nTPM]":"35.8","Tissue RNA - prostate [nTPM]":"34.3","Tissue RNA - rectum [nTPM]":"81.9","Tissue RNA - retina [nTPM]":"20.5","Tissue RNA - salivary gland [nTPM]":"49.9","Tissue RNA - seminal vesicle [nTPM]":"27.5","Tissue RNA - skeletal muscle [nTPM]":"81.0","Tissue RNA - skin 1 [nTPM]":"45.5","Tissue RNA - small intestine [nTPM]":"70.0","Tissue RNA - smooth muscle [nTPM]":"27.6","Tissue RNA - spinal cord [nTPM]":"26.9","Tissue RNA - spleen [nTPM]":"20.2","Tissue RNA - stomach 1 [nTPM]":"112.7","Tissue RNA - testis [nTPM]":"10.7","Tissue RNA - thalamus [nTPM]":"33.3","Tissue RNA - thymus [nTPM]":"20.1","Tissue RNA - thyroid gland [nTPM]":"49.8","Tissue RNA - tongue [nTPM]":"86.5","Tissue RNA - tonsil [nTPM]":"41.1","Tissue RNA - urinary bladder [nTPM]":"44.8","Tissue RNA - vagina [nTPM]":"41.3","Tissue RNA - white matter [nTPM]":"28.4","Cell RNA - A-431 [nTPM]":"72.4","Cell RNA - A549 [nTPM]":"72.7","Cell RNA - AF22 [nTPM]":"28.3","Cell RNA - AN3-CA [nTPM]":"109.0","Cell RNA - ASC diff [nTPM]":"120.4","Cell RNA - ASC TERT1 [nTPM]":"113.8","Cell RNA - BEWO [nTPM]":"41.0","Cell RNA - BJ [nTPM]":"56.2","Cell RNA - BJ hTERT+ [nTPM]":"69.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"44.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"48.0","Cell RNA - CACO-2 [nTPM]":"66.6","Cell RNA - CAPAN-2 [nTPM]":"140.4","Cell RNA - Daudi [nTPM]":"12.6","Cell RNA - EFO-21 [nTPM]":"59.8","Cell RNA - fHDF\/TERT166 [nTPM]":"77.7","Cell RNA - GAMG [nTPM]":"47.7","Cell RNA - HaCaT [nTPM]":"89.0","Cell RNA - HAP1 [nTPM]":"56.0","Cell RNA - HBEC3-KT [nTPM]":"83.9","Cell RNA - HBF TERT88 [nTPM]":"51.5","Cell RNA - HDLM-2 [nTPM]":"44.8","Cell RNA - HEK 293 [nTPM]":"20.0","Cell RNA - HEL [nTPM]":"50.8","Cell RNA - HeLa [nTPM]":"58.1","Cell RNA - Hep G2 [nTPM]":"103.6","Cell RNA - HHSteC [nTPM]":"93.5","Cell RNA - HL-60 [nTPM]":"66.5","Cell RNA - HMC-1 [nTPM]":"73.7","Cell RNA - HSkMC [nTPM]":"116.7","Cell RNA - hTCEpi [nTPM]":"98.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"51.9","Cell RNA - hTERT-HME1 [nTPM]":"53.3","Cell RNA - hTERT-RPE1 [nTPM]":"68.0","Cell RNA - HUVEC TERT2 [nTPM]":"82.1","Cell RNA - JURKAT [nTPM]":"37.9","Cell RNA - K-562 [nTPM]":"81.2","Cell RNA - Karpas-707 [nTPM]":"79.5","Cell RNA - LHCN-M2 [nTPM]":"52.5","Cell RNA - MCF7 [nTPM]":"43.5","Cell RNA - MOLT-4 [nTPM]":"27.7","Cell RNA - NB-4 [nTPM]":"72.5","Cell RNA - NTERA-2 [nTPM]":"29.0","Cell RNA - OE19 [nTPM]":"118.4","Cell RNA - PC-3 [nTPM]":"35.9","Cell RNA - REH [nTPM]":"35.9","Cell RNA - RH-30 [nTPM]":"46.2","Cell RNA - RPMI-8226 [nTPM]":"34.0","Cell RNA - RPTEC TERT1 [nTPM]":"92.5","Cell RNA - RT4 [nTPM]":"144.1","Cell RNA - SCLC-21H [nTPM]":"17.4","Cell RNA - SH-SY5Y [nTPM]":"44.3","Cell RNA - SiHa [nTPM]":"96.4","Cell RNA - SK-BR-3 [nTPM]":"178.2","Cell RNA - SK-MEL-30 [nTPM]":"48.7","Cell RNA - SuSa [nTPM]":"49.9","Cell RNA - T-47d [nTPM]":"101.0","Cell RNA - THP-1 [nTPM]":"66.3","Cell RNA - TIME [nTPM]":"108.3","Cell RNA - U-138 MG [nTPM]":"47.5","Cell RNA - U-2 OS [nTPM]":"50.3","Cell RNA - U-2197 [nTPM]":"76.9","Cell RNA - U-251 MG [nTPM]":"36.7","Cell RNA - U-266\/70 [nTPM]":"45.0","Cell RNA - U-266\/84 [nTPM]":"131.6","Cell RNA - U-698 [nTPM]":"59.4","Cell RNA - U-87 MG [nTPM]":"84.9","Cell RNA - U-937 [nTPM]":"42.2","Cell RNA - WM-115 [nTPM]":"44.1","Blood RNA - basophil [nTPM]":"255.5","Blood RNA - classical monocyte [nTPM]":"227.6","Blood RNA - eosinophil [nTPM]":"274.8","Blood RNA - gdT-cell [nTPM]":"49.5","Blood RNA - intermediate monocyte [nTPM]":"204.4","Blood RNA - MAIT T-cell [nTPM]":"51.5","Blood RNA - memory B-cell [nTPM]":"40.2","Blood RNA - memory CD4 T-cell [nTPM]":"46.2","Blood RNA - memory CD8 T-cell [nTPM]":"50.0","Blood RNA - myeloid DC [nTPM]":"152.1","Blood RNA - naive B-cell [nTPM]":"33.0","Blood RNA - naive CD4 T-cell [nTPM]":"29.1","Blood RNA - naive CD8 T-cell [nTPM]":"41.4","Blood RNA - neutrophil [nTPM]":"173.3","Blood RNA - NK-cell [nTPM]":"56.5","Blood RNA - non-classical monocyte [nTPM]":"207.4","Blood RNA - plasmacytoid DC [nTPM]":"95.1","Blood RNA - T-reg [nTPM]":"60.7","Blood RNA - total PBMC [nTPM]":"116.5","Brain RNA - amygdala [nTPM]":"22.1","Brain RNA - basal ganglia [nTPM]":"24.4","Brain RNA - cerebellum [nTPM]":"26.0","Brain RNA - cerebral cortex [nTPM]":"26.5","Brain RNA - hippocampal formation [nTPM]":"30.3","Brain RNA - hypothalamus [nTPM]":"32.9","Brain RNA - medulla oblongata [nTPM]":"32.9","Brain RNA - midbrain [nTPM]":"31.0","Brain RNA - pons [nTPM]":"35.8","Brain RNA - spinal cord [nTPM]":"26.9","Brain RNA - thalamus [nTPM]":"33.3","Brain RNA - white matter [nTPM]":"28.4","Single Cell Type RNA - Adipocytes [nTPM]":"28.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"117.3","Single Cell Type RNA - Astrocytes [nTPM]":"20.9","Single Cell Type RNA - B-cells [nTPM]":"26.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"72.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"62.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"48.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"20.5","Single Cell Type RNA - Bipolar cells [nTPM]":"11.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"101.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"39.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"80.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"243.1","Single Cell Type RNA - Club cells [nTPM]":"50.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"103.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"33.3","Single Cell Type RNA - dendritic cells [nTPM]":"38.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"434.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"389.4","Single Cell Type RNA - Ductal cells [nTPM]":"96.7","Single Cell Type RNA - Early spermatids [nTPM]":"52.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"68.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"48.8","Single Cell Type RNA - Endothelial cells [nTPM]":"39.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"55.6","Single Cell Type RNA - Erythroid cells [nTPM]":"58.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"24.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"150.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"62.4","Single Cell Type RNA - Fibroblasts [nTPM]":"38.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"112.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"114.4","Single Cell Type RNA - granulocytes [nTPM]":"37.4","Single Cell Type RNA - Granulosa cells [nTPM]":"18.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"78.1","Single Cell Type RNA - Hepatocytes [nTPM]":"353.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"68.5","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"136.2","Single Cell Type RNA - Ionocytes [nTPM]":"34.6","Single Cell Type RNA - Kupffer cells [nTPM]":"170.1","Single Cell Type RNA - Langerhans cells [nTPM]":"134.8","Single Cell Type RNA - Late spermatids [nTPM]":"122.6","Single Cell Type RNA - Leydig cells [nTPM]":"29.5","Single Cell Type RNA - Macrophages [nTPM]":"77.1","Single Cell Type RNA - Melanocytes [nTPM]":"129.9","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"113.4","Single Cell Type RNA - Muller glia cells [nTPM]":"32.7","Single Cell Type RNA - NK-cells [nTPM]":"36.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"23.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"173.9","Single Cell Type RNA - Paneth cells [nTPM]":"206.4","Single Cell Type RNA - Peritubular cells [nTPM]":"29.3","Single Cell Type RNA - Plasma cells [nTPM]":"24.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"80.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"425.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"231.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.3","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"46.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"41.4","Single Cell Type RNA - Spermatocytes [nTPM]":"13.7","Single Cell Type RNA - Spermatogonia [nTPM]":"19.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"50.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"108.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"66.9","Single Cell Type RNA - T-cells [nTPM]":"32.9","Single Cell Type RNA - Theca cells [nTPM]":"65.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"161.4","Single Cell Type RNA - Urothelial cells [nTPM]":"130.8"},{"Gene":"CHRNB1","Gene synonym":["CHRNB"],"Ensembl":"ENSG00000170175","Gene description":"Cholinergic receptor nicotinic beta 1 subunit","Uniprot":["P11230"],"Chromosome":"17","Position":"7445061-7457710","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"158.4","tongue":"57.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"39.0","Skeletal myocytes":"47.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"LHCN-M2":"34.6","RH-30":"71.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005822","CAB011200"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB011200":"AB_262151","HPA005822":"AB_1079484"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.0","Tissue RNA - adrenal gland [nTPM]":"30.6","Tissue RNA - amygdala [nTPM]":"6.9","Tissue RNA - appendix [nTPM]":"2.4","Tissue RNA - basal ganglia [nTPM]":"7.8","Tissue RNA - bone marrow [nTPM]":"9.1","Tissue RNA - breast [nTPM]":"6.7","Tissue RNA - cerebellum [nTPM]":"7.3","Tissue RNA - cerebral cortex [nTPM]":"7.5","Tissue RNA - cervix [nTPM]":"7.5","Tissue RNA - choroid plexus [nTPM]":"8.8","Tissue RNA - colon [nTPM]":"6.3","Tissue RNA - duodenum [nTPM]":"2.9","Tissue RNA - endometrium 1 [nTPM]":"6.6","Tissue RNA - epididymis [nTPM]":"5.1","Tissue RNA - esophagus [nTPM]":"7.0","Tissue RNA - fallopian tube [nTPM]":"5.4","Tissue RNA - gallbladder [nTPM]":"1.9","Tissue RNA - heart muscle [nTPM]":"11.5","Tissue RNA - hippocampal formation [nTPM]":"6.9","Tissue RNA - hypothalamus [nTPM]":"6.9","Tissue RNA - kidney [nTPM]":"10.7","Tissue RNA - liver [nTPM]":"16.5","Tissue RNA - lung [nTPM]":"5.1","Tissue RNA - lymph node [nTPM]":"3.6","Tissue RNA - medulla oblongata [nTPM]":"7.5","Tissue RNA - midbrain [nTPM]":"7.0","Tissue RNA - ovary [nTPM]":"5.4","Tissue RNA - pancreas [nTPM]":"16.5","Tissue RNA - parathyroid gland [nTPM]":"9.1","Tissue RNA - pituitary gland [nTPM]":"6.7","Tissue RNA - placenta [nTPM]":"6.7","Tissue RNA - pons [nTPM]":"7.3","Tissue RNA - prostate [nTPM]":"5.1","Tissue RNA - rectum [nTPM]":"2.5","Tissue RNA - retina [nTPM]":"3.2","Tissue RNA - salivary gland [nTPM]":"10.7","Tissue RNA - seminal vesicle [nTPM]":"3.0","Tissue RNA - skeletal muscle [nTPM]":"158.4","Tissue RNA - skin 1 [nTPM]":"8.1","Tissue RNA - small intestine [nTPM]":"5.5","Tissue RNA - smooth muscle [nTPM]":"3.2","Tissue RNA - spinal cord [nTPM]":"7.3","Tissue RNA - spleen [nTPM]":"7.9","Tissue RNA - stomach 1 [nTPM]":"5.2","Tissue RNA - testis [nTPM]":"3.2","Tissue RNA - thalamus [nTPM]":"7.1","Tissue RNA - thymus [nTPM]":"6.5","Tissue RNA - thyroid gland [nTPM]":"13.0","Tissue RNA - tongue [nTPM]":"57.7","Tissue RNA - tonsil [nTPM]":"3.9","Tissue RNA - urinary bladder [nTPM]":"5.5","Tissue RNA - vagina [nTPM]":"7.2","Tissue RNA - white matter [nTPM]":"8.1","Cell RNA - A-431 [nTPM]":"1.6","Cell RNA - A549 [nTPM]":"2.2","Cell RNA - AF22 [nTPM]":"3.8","Cell RNA - AN3-CA [nTPM]":"4.5","Cell RNA - ASC diff [nTPM]":"6.0","Cell RNA - ASC TERT1 [nTPM]":"4.0","Cell RNA - BEWO [nTPM]":"8.6","Cell RNA - BJ [nTPM]":"1.1","Cell RNA - BJ hTERT+ [nTPM]":"3.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.6","Cell RNA - CACO-2 [nTPM]":"1.3","Cell RNA - CAPAN-2 [nTPM]":"2.0","Cell RNA - Daudi [nTPM]":"6.2","Cell RNA - EFO-21 [nTPM]":"4.0","Cell RNA - fHDF\/TERT166 [nTPM]":"2.5","Cell RNA - GAMG [nTPM]":"2.0","Cell RNA - HaCaT [nTPM]":"13.6","Cell RNA - HAP1 [nTPM]":"1.4","Cell RNA - HBEC3-KT [nTPM]":"25.1","Cell RNA - HBF TERT88 [nTPM]":"2.0","Cell RNA - HDLM-2 [nTPM]":"7.6","Cell RNA - HEK 293 [nTPM]":"4.8","Cell RNA - HEL [nTPM]":"3.5","Cell RNA - HeLa [nTPM]":"2.3","Cell RNA - Hep G2 [nTPM]":"8.1","Cell RNA - HHSteC [nTPM]":"2.6","Cell RNA - HL-60 [nTPM]":"2.2","Cell RNA - HMC-1 [nTPM]":"8.6","Cell RNA - HSkMC [nTPM]":"8.8","Cell RNA - hTCEpi [nTPM]":"6.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.4","Cell RNA - hTERT-HME1 [nTPM]":"11.0","Cell RNA - hTERT-RPE1 [nTPM]":"9.3","Cell RNA - HUVEC TERT2 [nTPM]":"3.8","Cell RNA - JURKAT [nTPM]":"12.0","Cell RNA - K-562 [nTPM]":"4.6","Cell RNA - Karpas-707 [nTPM]":"3.4","Cell RNA - LHCN-M2 [nTPM]":"34.6","Cell RNA - MCF7 [nTPM]":"1.0","Cell RNA - MOLT-4 [nTPM]":"6.7","Cell RNA - NB-4 [nTPM]":"4.1","Cell RNA - NTERA-2 [nTPM]":"2.7","Cell RNA - OE19 [nTPM]":"1.5","Cell RNA - PC-3 [nTPM]":"1.1","Cell RNA - REH [nTPM]":"4.4","Cell RNA - RH-30 [nTPM]":"71.0","Cell RNA - RPMI-8226 [nTPM]":"15.8","Cell RNA - RPTEC TERT1 [nTPM]":"15.3","Cell RNA - RT4 [nTPM]":"1.2","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"11.1","Cell RNA - SiHa [nTPM]":"2.4","Cell RNA - SK-BR-3 [nTPM]":"4.0","Cell RNA - SK-MEL-30 [nTPM]":"4.7","Cell RNA - SuSa [nTPM]":"5.9","Cell RNA - T-47d [nTPM]":"3.9","Cell RNA - THP-1 [nTPM]":"3.0","Cell RNA - TIME [nTPM]":"3.6","Cell RNA - U-138 MG [nTPM]":"2.3","Cell RNA - U-2 OS [nTPM]":"6.4","Cell RNA - U-2197 [nTPM]":"1.7","Cell RNA - U-251 MG [nTPM]":"5.0","Cell RNA - U-266\/70 [nTPM]":"8.1","Cell RNA - U-266\/84 [nTPM]":"9.6","Cell RNA - U-698 [nTPM]":"1.7","Cell RNA - U-87 MG [nTPM]":"2.1","Cell RNA - U-937 [nTPM]":"4.9","Cell RNA - WM-115 [nTPM]":"2.1","Blood RNA - basophil [nTPM]":"9.9","Blood RNA - classical monocyte [nTPM]":"5.4","Blood RNA - eosinophil [nTPM]":"13.6","Blood RNA - gdT-cell [nTPM]":"7.9","Blood RNA - intermediate monocyte [nTPM]":"6.3","Blood RNA - MAIT T-cell [nTPM]":"6.1","Blood RNA - memory B-cell [nTPM]":"6.7","Blood RNA - memory CD4 T-cell [nTPM]":"8.7","Blood RNA - memory CD8 T-cell [nTPM]":"8.0","Blood RNA - myeloid DC [nTPM]":"7.0","Blood RNA - naive B-cell [nTPM]":"7.0","Blood RNA - naive CD4 T-cell [nTPM]":"7.0","Blood RNA - naive CD8 T-cell [nTPM]":"9.2","Blood RNA - neutrophil [nTPM]":"1.7","Blood RNA - NK-cell [nTPM]":"11.0","Blood RNA - non-classical monocyte [nTPM]":"10.4","Blood RNA - plasmacytoid DC [nTPM]":"5.2","Blood RNA - T-reg [nTPM]":"7.9","Blood RNA - total PBMC [nTPM]":"6.1","Brain RNA - amygdala [nTPM]":"6.9","Brain RNA - basal ganglia [nTPM]":"7.8","Brain RNA - cerebellum [nTPM]":"7.3","Brain RNA - cerebral cortex [nTPM]":"7.5","Brain RNA - hippocampal formation [nTPM]":"6.9","Brain RNA - hypothalamus [nTPM]":"6.9","Brain RNA - medulla oblongata [nTPM]":"7.5","Brain RNA - midbrain [nTPM]":"7.0","Brain RNA - pons [nTPM]":"7.3","Brain RNA - spinal cord [nTPM]":"7.3","Brain RNA - thalamus [nTPM]":"7.1","Brain RNA - white matter [nTPM]":"8.1","Single Cell Type RNA - Adipocytes [nTPM]":"8.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"4.6","Single Cell Type RNA - B-cells [nTPM]":"8.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"3.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"7.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"39.0","Single Cell Type RNA - dendritic cells [nTPM]":"17.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"16.1","Single Cell Type RNA - Early spermatids [nTPM]":"2.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.1","Single Cell Type RNA - Endothelial cells [nTPM]":"10.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"3.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.4","Single Cell Type RNA - Fibroblasts [nTPM]":"8.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.1","Single Cell Type RNA - granulocytes [nTPM]":"13.3","Single Cell Type RNA - Granulosa cells [nTPM]":"5.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.4","Single Cell Type RNA - Hepatocytes [nTPM]":"10.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.6","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.8","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"7.2","Single Cell Type RNA - Langerhans cells [nTPM]":"8.7","Single Cell Type RNA - Late spermatids [nTPM]":"2.1","Single Cell Type RNA - Leydig cells [nTPM]":"21.8","Single Cell Type RNA - Macrophages [nTPM]":"7.9","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"17.0","Single Cell Type RNA - Muller glia cells [nTPM]":"14.0","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.3","Single Cell Type RNA - Paneth cells [nTPM]":"4.9","Single Cell Type RNA - Peritubular cells [nTPM]":"17.0","Single Cell Type RNA - Plasma cells [nTPM]":"5.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"47.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.1","Single Cell Type RNA - Spermatocytes [nTPM]":"2.8","Single Cell Type RNA - Spermatogonia [nTPM]":"2.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"30.4","Single Cell Type RNA - T-cells [nTPM]":"11.2","Single Cell Type RNA - Theca cells [nTPM]":"12.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.9","Single Cell Type RNA - Urothelial cells [nTPM]":"3.8"},{"Gene":"CHRND","Gene synonym":["ACHRD"],"Ensembl":"ENSG00000135902","Gene description":"Cholinergic receptor nicotinic delta subunit","Uniprot":["Q07001"],"Chromosome":"2","Position":"232525993-232536667","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"skeletal muscle":"57.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Muller glia cells":"4.0","Skeletal myocytes":"4.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"head and neck cancer":"1.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"49","RNA cell line specific nTPM":{"RH-30":"99.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056404","HPA065404"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 37: Myocytes - Muscle contraction","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA056404":"AB_2732603","HPA065404":"AB_2732734"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"6.3","Tissue RNA - salivary gland [nTPM]":"0.7","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"57.6","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"6.3","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"2.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.9","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"99.4","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.8","Cell RNA - SH-SY5Y [nTPM]":"0.4","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CHRNE","Gene synonym":["ACHRE"],"Ensembl":"ENSG00000108556","Gene description":"Cholinergic receptor nicotinic epsilon subunit","Uniprot":["Q04844"],"Chromosome":"17","Position":"4897771-4934438","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"heart muscle":"55.3","pituitary gland":"27.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Late spermatids":"161.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"2.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"HEL":"5.0","HMC-1":"11.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"14","RNA pig brain regional specific nTPM":{"basal ganglia":"6.3"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.7","Tissue RNA - adrenal gland [nTPM]":"0.4","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"0.7","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"0.7","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"1.3","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.6","Tissue RNA - gallbladder [nTPM]":"1.0","Tissue RNA - heart muscle [nTPM]":"55.3","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"1.0","Tissue RNA - liver [nTPM]":"3.5","Tissue RNA - lung [nTPM]":"0.8","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"1.7","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"27.6","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.6","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"5.1","Tissue RNA - salivary gland [nTPM]":"0.8","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"1.8","Tissue RNA - skin 1 [nTPM]":"2.2","Tissue RNA - small intestine [nTPM]":"0.8","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"1.8","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"2.1","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"5.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.8","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"11.5","Cell RNA - HSkMC [nTPM]":"0.7","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.9","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"1.3","Blood RNA - gdT-cell [nTPM]":"2.5","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"4.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"4.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"5.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.6","Single Cell Type RNA - dendritic cells [nTPM]":"10.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"27.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.1","Single Cell Type RNA - Endothelial cells [nTPM]":"3.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.3","Single Cell Type RNA - Fibroblasts [nTPM]":"2.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.8","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"1.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.9","Single Cell Type RNA - Hepatocytes [nTPM]":"7.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.4","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"13.0","Single Cell Type RNA - Late spermatids [nTPM]":"161.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"9.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"5.3","Single Cell Type RNA - Muller glia cells [nTPM]":"1.1","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"3.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.1","Single Cell Type RNA - Spermatocytes [nTPM]":"5.6","Single Cell Type RNA - Spermatogonia [nTPM]":"8.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.1","Single Cell Type RNA - T-cells [nTPM]":"3.5","Single Cell Type RNA - Theca cells [nTPM]":"6.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"CHRNG","Gene synonym":["ACHRG"],"Ensembl":"ENSG00000196811","Gene description":"Cholinergic receptor nicotinic gamma subunit","Uniprot":["P07510"],"Chromosome":"2","Position":"232539692-232548115","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"23","RNA tissue specific nTPM":{"skeletal muscle":"32.0"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"0.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"19","RNA cell line specific nTPM":{"HSkMC":"2.7","RH-30":"7.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 37: Myocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"32.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"1.4","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"2.7","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"7.5","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CHST11","Gene synonym":["C4ST","C4St-1","C4ST1","HSA269537"],"Ensembl":"ENSG00000171310","Gene description":"Carbohydrate sulfotransferase 11","Uniprot":["Q9NPF2"],"Chromosome":"12","Position":"104455295-104762014","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"39.0","choroid plexus":"59.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Microglial cells":"281.1","Oligodendrocyte precursor cells":"1012.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"12.7","eosinophil":"11.2","neutrophil":"15.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"15.6"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052828"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"55000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA052828":"AB_2681966"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.59e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.42e-4"},"Tissue RNA - adipose tissue [nTPM]":"5.0","Tissue RNA - adrenal gland [nTPM]":"10.2","Tissue RNA - amygdala [nTPM]":"14.5","Tissue RNA - appendix [nTPM]":"20.1","Tissue RNA - basal ganglia [nTPM]":"13.9","Tissue RNA - bone marrow [nTPM]":"39.0","Tissue RNA - breast [nTPM]":"3.5","Tissue RNA - cerebellum [nTPM]":"11.1","Tissue RNA - cerebral cortex [nTPM]":"14.1","Tissue RNA - cervix [nTPM]":"5.6","Tissue RNA - choroid plexus [nTPM]":"59.1","Tissue RNA - colon [nTPM]":"4.2","Tissue RNA - duodenum [nTPM]":"3.0","Tissue RNA - endometrium 1 [nTPM]":"11.9","Tissue RNA - epididymis [nTPM]":"13.3","Tissue RNA - esophagus [nTPM]":"3.4","Tissue RNA - fallopian tube [nTPM]":"3.7","Tissue RNA - gallbladder [nTPM]":"9.4","Tissue RNA - heart muscle [nTPM]":"4.5","Tissue RNA - hippocampal formation [nTPM]":"15.0","Tissue RNA - hypothalamus [nTPM]":"16.0","Tissue RNA - kidney [nTPM]":"3.6","Tissue RNA - liver [nTPM]":"3.0","Tissue RNA - lung [nTPM]":"12.2","Tissue RNA - lymph node [nTPM]":"15.2","Tissue RNA - medulla oblongata [nTPM]":"17.9","Tissue RNA - midbrain [nTPM]":"16.4","Tissue RNA - ovary [nTPM]":"6.2","Tissue RNA - pancreas [nTPM]":"4.6","Tissue RNA - parathyroid gland [nTPM]":"1.3","Tissue RNA - pituitary gland [nTPM]":"4.5","Tissue RNA - placenta [nTPM]":"15.5","Tissue RNA - pons [nTPM]":"17.1","Tissue RNA - prostate [nTPM]":"3.9","Tissue RNA - rectum [nTPM]":"4.0","Tissue RNA - retina [nTPM]":"2.2","Tissue RNA - salivary gland [nTPM]":"2.2","Tissue RNA - seminal vesicle [nTPM]":"8.0","Tissue RNA - skeletal muscle [nTPM]":"1.1","Tissue RNA - skin 1 [nTPM]":"1.7","Tissue RNA - small intestine [nTPM]":"6.2","Tissue RNA - smooth muscle [nTPM]":"10.9","Tissue RNA - spinal cord [nTPM]":"13.1","Tissue RNA - spleen [nTPM]":"12.8","Tissue RNA - stomach 1 [nTPM]":"6.3","Tissue RNA - testis [nTPM]":"2.3","Tissue RNA - thalamus [nTPM]":"17.3","Tissue RNA - thymus [nTPM]":"19.5","Tissue RNA - thyroid gland [nTPM]":"3.3","Tissue RNA - tongue [nTPM]":"1.0","Tissue RNA - tonsil [nTPM]":"11.7","Tissue RNA - urinary bladder [nTPM]":"8.3","Tissue RNA - vagina [nTPM]":"3.8","Tissue RNA - white matter [nTPM]":"17.5","Cell RNA - A-431 [nTPM]":"38.8","Cell RNA - A549 [nTPM]":"18.2","Cell RNA - AF22 [nTPM]":"8.2","Cell RNA - AN3-CA [nTPM]":"5.3","Cell RNA - ASC diff [nTPM]":"20.5","Cell RNA - ASC TERT1 [nTPM]":"10.0","Cell RNA - BEWO [nTPM]":"27.8","Cell RNA - BJ [nTPM]":"3.1","Cell RNA - BJ hTERT+ [nTPM]":"1.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.5","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"51.2","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"5.6","Cell RNA - fHDF\/TERT166 [nTPM]":"5.4","Cell RNA - GAMG [nTPM]":"42.3","Cell RNA - HaCaT [nTPM]":"9.9","Cell RNA - HAP1 [nTPM]":"4.9","Cell RNA - HBEC3-KT [nTPM]":"20.8","Cell RNA - HBF TERT88 [nTPM]":"2.2","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"7.1","Cell RNA - HEL [nTPM]":"53.2","Cell RNA - HeLa [nTPM]":"4.8","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"3.1","Cell RNA - HL-60 [nTPM]":"62.4","Cell RNA - HMC-1 [nTPM]":"60.6","Cell RNA - HSkMC [nTPM]":"3.7","Cell RNA - hTCEpi [nTPM]":"2.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.9","Cell RNA - hTERT-HME1 [nTPM]":"5.4","Cell RNA - hTERT-RPE1 [nTPM]":"30.7","Cell RNA - HUVEC TERT2 [nTPM]":"13.2","Cell RNA - JURKAT [nTPM]":"74.4","Cell RNA - K-562 [nTPM]":"82.8","Cell RNA - Karpas-707 [nTPM]":"13.2","Cell RNA - LHCN-M2 [nTPM]":"3.5","Cell RNA - MCF7 [nTPM]":"9.7","Cell RNA - MOLT-4 [nTPM]":"47.8","Cell RNA - NB-4 [nTPM]":"73.1","Cell RNA - NTERA-2 [nTPM]":"6.6","Cell RNA - OE19 [nTPM]":"0.4","Cell RNA - PC-3 [nTPM]":"7.0","Cell RNA - REH [nTPM]":"54.0","Cell RNA - RH-30 [nTPM]":"27.3","Cell RNA - RPMI-8226 [nTPM]":"12.9","Cell RNA - RPTEC TERT1 [nTPM]":"17.0","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"13.6","Cell RNA - SH-SY5Y [nTPM]":"21.9","Cell RNA - SiHa [nTPM]":"2.1","Cell RNA - SK-BR-3 [nTPM]":"26.3","Cell RNA - SK-MEL-30 [nTPM]":"48.3","Cell RNA - SuSa [nTPM]":"7.2","Cell RNA - T-47d [nTPM]":"7.7","Cell RNA - THP-1 [nTPM]":"62.7","Cell RNA - TIME [nTPM]":"29.2","Cell RNA - U-138 MG [nTPM]":"5.7","Cell RNA - U-2 OS [nTPM]":"6.2","Cell RNA - U-2197 [nTPM]":"29.4","Cell RNA - U-251 MG [nTPM]":"32.3","Cell RNA - U-266\/70 [nTPM]":"67.2","Cell RNA - U-266\/84 [nTPM]":"75.9","Cell RNA - U-698 [nTPM]":"10.6","Cell RNA - U-87 MG [nTPM]":"26.3","Cell RNA - U-937 [nTPM]":"43.5","Cell RNA - WM-115 [nTPM]":"57.7","Blood RNA - basophil [nTPM]":"12.7","Blood RNA - classical monocyte [nTPM]":"1.4","Blood RNA - eosinophil [nTPM]":"11.2","Blood RNA - gdT-cell [nTPM]":"3.0","Blood RNA - intermediate monocyte [nTPM]":"1.4","Blood RNA - MAIT T-cell [nTPM]":"1.7","Blood RNA - memory B-cell [nTPM]":"1.0","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"2.2","Blood RNA - myeloid DC [nTPM]":"0.8","Blood RNA - naive B-cell [nTPM]":"2.8","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"15.6","Blood RNA - NK-cell [nTPM]":"1.6","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"2.9","Blood RNA - T-reg [nTPM]":"3.2","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"14.5","Brain RNA - basal ganglia [nTPM]":"13.9","Brain RNA - cerebellum [nTPM]":"11.1","Brain RNA - cerebral cortex [nTPM]":"14.1","Brain RNA - hippocampal formation [nTPM]":"15.0","Brain RNA - hypothalamus [nTPM]":"16.0","Brain RNA - medulla oblongata [nTPM]":"17.9","Brain RNA - midbrain [nTPM]":"16.4","Brain RNA - pons [nTPM]":"17.1","Brain RNA - spinal cord [nTPM]":"13.1","Brain RNA - thalamus [nTPM]":"17.3","Brain RNA - white matter [nTPM]":"17.5","Single Cell Type RNA - Adipocytes [nTPM]":"8.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.1","Single Cell Type RNA - Astrocytes [nTPM]":"142.4","Single Cell Type RNA - B-cells [nTPM]":"33.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"3.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"6.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"41.6","Single Cell Type RNA - dendritic cells [nTPM]":"45.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"4.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"24.7","Single Cell Type RNA - Endothelial cells [nTPM]":"12.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"36.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"43.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"61.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.0","Single Cell Type RNA - Fibroblasts [nTPM]":"9.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.9","Single Cell Type RNA - granulocytes [nTPM]":"41.3","Single Cell Type RNA - Granulosa cells [nTPM]":"1.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"42.6","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"114.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"26.8","Single Cell Type RNA - Langerhans cells [nTPM]":"42.9","Single Cell Type RNA - Late spermatids [nTPM]":"2.0","Single Cell Type RNA - Leydig cells [nTPM]":"7.5","Single Cell Type RNA - Macrophages [nTPM]":"56.5","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"281.1","Single Cell Type RNA - monocytes [nTPM]":"65.6","Single Cell Type RNA - Muller glia cells [nTPM]":"2.3","Single Cell Type RNA - NK-cells [nTPM]":"30.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1012.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"28.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"17.0","Single Cell Type RNA - Plasma cells [nTPM]":"64.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"2.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"26.5","Single Cell Type RNA - T-cells [nTPM]":"49.0","Single Cell Type RNA - Theca cells [nTPM]":"15.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"3.7"},{"Gene":"CHST14","Gene synonym":["D4ST-1","D4ST1","HD4ST"],"Ensembl":"ENSG00000169105","Gene description":"Carbohydrate sulfotransferase 14","Uniprot":["Q8NCH0"],"Chromosome":"15","Position":"40470984-40473158","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Carbohydrate metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Ehlers-Danlos syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"46.5","Extravillous trophoblasts":"32.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"7.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057697","HPA071601"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"20000","Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA057697":"AB_2683505","HPA071601":"AB_2686425"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Tissue RNA - adipose tissue [nTPM]":"14.2","Tissue RNA - adrenal gland [nTPM]":"9.6","Tissue RNA - amygdala [nTPM]":"6.8","Tissue RNA - appendix [nTPM]":"7.7","Tissue RNA - basal ganglia [nTPM]":"7.5","Tissue RNA - bone marrow [nTPM]":"3.4","Tissue RNA - breast [nTPM]":"13.7","Tissue RNA - cerebellum [nTPM]":"7.0","Tissue RNA - cerebral cortex [nTPM]":"6.5","Tissue RNA - cervix [nTPM]":"22.0","Tissue RNA - choroid plexus [nTPM]":"7.3","Tissue RNA - colon [nTPM]":"11.8","Tissue RNA - duodenum [nTPM]":"4.5","Tissue RNA - endometrium 1 [nTPM]":"21.6","Tissue RNA - epididymis [nTPM]":"8.0","Tissue RNA - esophagus [nTPM]":"8.7","Tissue RNA - fallopian tube [nTPM]":"16.5","Tissue RNA - gallbladder [nTPM]":"11.3","Tissue RNA - heart muscle [nTPM]":"13.8","Tissue RNA - hippocampal formation [nTPM]":"6.2","Tissue RNA - hypothalamus [nTPM]":"7.0","Tissue RNA - kidney [nTPM]":"10.1","Tissue RNA - liver [nTPM]":"8.8","Tissue RNA - lung [nTPM]":"13.0","Tissue RNA - lymph node [nTPM]":"8.5","Tissue RNA - medulla oblongata [nTPM]":"8.0","Tissue RNA - midbrain [nTPM]":"7.1","Tissue RNA - ovary [nTPM]":"21.1","Tissue RNA - pancreas [nTPM]":"8.1","Tissue RNA - parathyroid gland [nTPM]":"11.3","Tissue RNA - pituitary gland [nTPM]":"14.4","Tissue RNA - placenta [nTPM]":"27.0","Tissue RNA - pons [nTPM]":"7.2","Tissue RNA - prostate [nTPM]":"14.6","Tissue RNA - rectum [nTPM]":"4.6","Tissue RNA - retina [nTPM]":"1.6","Tissue RNA - salivary gland [nTPM]":"11.0","Tissue RNA - seminal vesicle [nTPM]":"15.4","Tissue RNA - skeletal muscle [nTPM]":"5.0","Tissue RNA - skin 1 [nTPM]":"9.1","Tissue RNA - small intestine [nTPM]":"9.9","Tissue RNA - smooth muscle [nTPM]":"12.6","Tissue RNA - spinal cord [nTPM]":"7.5","Tissue RNA - spleen [nTPM]":"13.6","Tissue RNA - stomach 1 [nTPM]":"9.4","Tissue RNA - testis [nTPM]":"7.9","Tissue RNA - thalamus [nTPM]":"7.0","Tissue RNA - thymus [nTPM]":"8.6","Tissue RNA - thyroid gland [nTPM]":"15.8","Tissue RNA - tongue [nTPM]":"7.4","Tissue RNA - tonsil [nTPM]":"7.5","Tissue RNA - urinary bladder [nTPM]":"16.1","Tissue RNA - vagina [nTPM]":"16.1","Tissue RNA - white matter [nTPM]":"7.3","Cell RNA - A-431 [nTPM]":"26.2","Cell RNA - A549 [nTPM]":"17.1","Cell RNA - AF22 [nTPM]":"26.4","Cell RNA - AN3-CA [nTPM]":"71.6","Cell RNA - ASC diff [nTPM]":"40.4","Cell RNA - ASC TERT1 [nTPM]":"31.0","Cell RNA - BEWO [nTPM]":"43.0","Cell RNA - BJ [nTPM]":"25.2","Cell RNA - BJ hTERT+ [nTPM]":"47.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"43.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"40.9","Cell RNA - CACO-2 [nTPM]":"21.2","Cell RNA - CAPAN-2 [nTPM]":"12.8","Cell RNA - Daudi [nTPM]":"4.3","Cell RNA - EFO-21 [nTPM]":"37.6","Cell RNA - fHDF\/TERT166 [nTPM]":"42.7","Cell RNA - GAMG [nTPM]":"76.7","Cell RNA - HaCaT [nTPM]":"43.7","Cell RNA - HAP1 [nTPM]":"23.7","Cell RNA - HBEC3-KT [nTPM]":"14.2","Cell RNA - HBF TERT88 [nTPM]":"20.3","Cell RNA - HDLM-2 [nTPM]":"31.5","Cell RNA - HEK 293 [nTPM]":"15.0","Cell RNA - HEL [nTPM]":"13.4","Cell RNA - HeLa [nTPM]":"16.9","Cell RNA - Hep G2 [nTPM]":"19.8","Cell RNA - HHSteC [nTPM]":"22.5","Cell RNA - HL-60 [nTPM]":"5.7","Cell RNA - HMC-1 [nTPM]":"33.4","Cell RNA - HSkMC [nTPM]":"38.3","Cell RNA - hTCEpi [nTPM]":"11.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.4","Cell RNA - hTERT-HME1 [nTPM]":"11.6","Cell RNA - hTERT-RPE1 [nTPM]":"47.8","Cell RNA - HUVEC TERT2 [nTPM]":"39.2","Cell RNA - JURKAT [nTPM]":"15.1","Cell RNA - K-562 [nTPM]":"13.6","Cell RNA - Karpas-707 [nTPM]":"15.0","Cell RNA - LHCN-M2 [nTPM]":"32.6","Cell RNA - MCF7 [nTPM]":"20.1","Cell RNA - MOLT-4 [nTPM]":"9.6","Cell RNA - NB-4 [nTPM]":"29.8","Cell RNA - NTERA-2 [nTPM]":"17.0","Cell RNA - OE19 [nTPM]":"7.9","Cell RNA - PC-3 [nTPM]":"20.1","Cell RNA - REH [nTPM]":"26.2","Cell RNA - RH-30 [nTPM]":"33.4","Cell RNA - RPMI-8226 [nTPM]":"7.6","Cell RNA - RPTEC TERT1 [nTPM]":"29.5","Cell RNA - RT4 [nTPM]":"13.3","Cell RNA - SCLC-21H [nTPM]":"19.7","Cell RNA - SH-SY5Y [nTPM]":"30.2","Cell RNA - SiHa [nTPM]":"22.2","Cell RNA - SK-BR-3 [nTPM]":"24.4","Cell RNA - SK-MEL-30 [nTPM]":"8.4","Cell RNA - SuSa [nTPM]":"31.9","Cell RNA - T-47d [nTPM]":"35.7","Cell RNA - THP-1 [nTPM]":"23.9","Cell RNA - TIME [nTPM]":"31.9","Cell RNA - U-138 MG [nTPM]":"73.0","Cell RNA - U-2 OS [nTPM]":"27.1","Cell RNA - U-2197 [nTPM]":"23.3","Cell RNA - U-251 MG [nTPM]":"25.5","Cell RNA - U-266\/70 [nTPM]":"30.3","Cell RNA - U-266\/84 [nTPM]":"22.6","Cell RNA - U-698 [nTPM]":"12.2","Cell RNA - U-87 MG [nTPM]":"32.8","Cell RNA - U-937 [nTPM]":"19.6","Cell RNA - WM-115 [nTPM]":"53.7","Blood RNA - basophil [nTPM]":"7.6","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"2.2","Blood RNA - gdT-cell [nTPM]":"2.2","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.9","Blood RNA - myeloid DC [nTPM]":"2.0","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.9","Blood RNA - naive CD8 T-cell [nTPM]":"0.8","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"3.3","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"6.8","Brain RNA - basal ganglia [nTPM]":"7.5","Brain RNA - cerebellum [nTPM]":"7.0","Brain RNA - cerebral cortex [nTPM]":"6.5","Brain RNA - hippocampal formation [nTPM]":"6.2","Brain RNA - hypothalamus [nTPM]":"7.0","Brain RNA - medulla oblongata [nTPM]":"8.0","Brain RNA - midbrain [nTPM]":"7.1","Brain RNA - pons [nTPM]":"7.2","Brain RNA - spinal cord [nTPM]":"7.5","Brain RNA - thalamus [nTPM]":"7.0","Brain RNA - white matter [nTPM]":"7.3","Single Cell Type RNA - Adipocytes [nTPM]":"10.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"5.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"4.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"46.5","Single Cell Type RNA - dendritic cells [nTPM]":"3.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"7.7","Single Cell Type RNA - Early spermatids [nTPM]":"1.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.5","Single Cell Type RNA - Endothelial cells [nTPM]":"10.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"10.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"32.4","Single Cell Type RNA - Fibroblasts [nTPM]":"19.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.6","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"14.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.4","Single Cell Type RNA - Hepatocytes [nTPM]":"3.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.3","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.4","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"5.6","Single Cell Type RNA - Langerhans cells [nTPM]":"3.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"17.7","Single Cell Type RNA - Macrophages [nTPM]":"5.6","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"3.4","Single Cell Type RNA - Muller glia cells [nTPM]":"9.8","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"11.7","Single Cell Type RNA - Plasma cells [nTPM]":"1.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.2","Single Cell Type RNA - Spermatocytes [nTPM]":"7.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"13.5","Single Cell Type RNA - T-cells [nTPM]":"4.9","Single Cell Type RNA - Theca cells [nTPM]":"3.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.9","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"CHST3","Gene synonym":["C6ST","C6ST1"],"Ensembl":"ENSG00000122863","Gene description":"Carbohydrate sulfotransferase 3","Uniprot":["Q7LGC8"],"Chromosome":"10","Position":"71964395-72013558","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Carbohydrate metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"26.9","Oligodendrocyte precursor cells":"26.7","Oligodendrocytes":"27.1","Skeletal myocytes":"26.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-251 MG":"65.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047523","HPA055704"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"690000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Golgi apparatus","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA047523":"AB_2680075","HPA055704":"AB_2682891"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-3"},"Tissue RNA - adipose tissue [nTPM]":"18.4","Tissue RNA - adrenal gland [nTPM]":"13.4","Tissue RNA - amygdala [nTPM]":"10.7","Tissue RNA - appendix [nTPM]":"5.5","Tissue RNA - basal ganglia [nTPM]":"17.9","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"11.4","Tissue RNA - cerebellum [nTPM]":"16.8","Tissue RNA - cerebral cortex [nTPM]":"11.5","Tissue RNA - cervix [nTPM]":"10.7","Tissue RNA - choroid plexus [nTPM]":"6.2","Tissue RNA - colon [nTPM]":"11.9","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"16.0","Tissue RNA - epididymis [nTPM]":"3.7","Tissue RNA - esophagus [nTPM]":"6.4","Tissue RNA - fallopian tube [nTPM]":"12.9","Tissue RNA - gallbladder [nTPM]":"4.7","Tissue RNA - heart muscle [nTPM]":"14.3","Tissue RNA - hippocampal formation [nTPM]":"9.9","Tissue RNA - hypothalamus [nTPM]":"12.9","Tissue RNA - kidney [nTPM]":"7.9","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"7.9","Tissue RNA - lymph node [nTPM]":"1.6","Tissue RNA - medulla oblongata [nTPM]":"27.9","Tissue RNA - midbrain [nTPM]":"18.2","Tissue RNA - ovary [nTPM]":"20.6","Tissue RNA - pancreas [nTPM]":"4.6","Tissue RNA - parathyroid gland [nTPM]":"1.2","Tissue RNA - pituitary gland [nTPM]":"4.6","Tissue RNA - placenta [nTPM]":"8.0","Tissue RNA - pons [nTPM]":"19.8","Tissue RNA - prostate [nTPM]":"11.1","Tissue RNA - rectum [nTPM]":"2.1","Tissue RNA - retina [nTPM]":"2.1","Tissue RNA - salivary gland [nTPM]":"6.4","Tissue RNA - seminal vesicle [nTPM]":"14.8","Tissue RNA - skeletal muscle [nTPM]":"17.7","Tissue RNA - skin 1 [nTPM]":"8.7","Tissue RNA - small intestine [nTPM]":"5.4","Tissue RNA - smooth muscle [nTPM]":"17.1","Tissue RNA - spinal cord [nTPM]":"14.0","Tissue RNA - spleen [nTPM]":"2.5","Tissue RNA - stomach 1 [nTPM]":"14.7","Tissue RNA - testis [nTPM]":"18.1","Tissue RNA - thalamus [nTPM]":"17.3","Tissue RNA - thymus [nTPM]":"4.2","Tissue RNA - thyroid gland [nTPM]":"5.5","Tissue RNA - tongue [nTPM]":"9.0","Tissue RNA - tonsil [nTPM]":"1.4","Tissue RNA - urinary bladder [nTPM]":"9.4","Tissue RNA - vagina [nTPM]":"8.4","Tissue RNA - white matter [nTPM]":"25.3","Cell RNA - A-431 [nTPM]":"15.4","Cell RNA - A549 [nTPM]":"16.4","Cell RNA - AF22 [nTPM]":"8.2","Cell RNA - AN3-CA [nTPM]":"20.3","Cell RNA - ASC diff [nTPM]":"36.6","Cell RNA - ASC TERT1 [nTPM]":"14.4","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"32.0","Cell RNA - BJ hTERT+ [nTPM]":"30.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.8","Cell RNA - CACO-2 [nTPM]":"14.4","Cell RNA - CAPAN-2 [nTPM]":"30.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"21.4","Cell RNA - fHDF\/TERT166 [nTPM]":"37.9","Cell RNA - GAMG [nTPM]":"15.5","Cell RNA - HaCaT [nTPM]":"19.7","Cell RNA - HAP1 [nTPM]":"7.4","Cell RNA - HBEC3-KT [nTPM]":"21.9","Cell RNA - HBF TERT88 [nTPM]":"15.3","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"5.5","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"27.8","Cell RNA - Hep G2 [nTPM]":"13.8","Cell RNA - HHSteC [nTPM]":"18.7","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"19.8","Cell RNA - hTCEpi [nTPM]":"24.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.0","Cell RNA - hTERT-HME1 [nTPM]":"25.9","Cell RNA - hTERT-RPE1 [nTPM]":"37.3","Cell RNA - HUVEC TERT2 [nTPM]":"5.7","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"4.7","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"20.6","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"3.5","Cell RNA - OE19 [nTPM]":"0.5","Cell RNA - PC-3 [nTPM]":"5.3","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"9.9","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"26.9","Cell RNA - RT4 [nTPM]":"15.7","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"8.1","Cell RNA - SiHa [nTPM]":"24.2","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"24.1","Cell RNA - SuSa [nTPM]":"9.9","Cell RNA - T-47d [nTPM]":"1.8","Cell RNA - THP-1 [nTPM]":"3.1","Cell RNA - TIME [nTPM]":"11.9","Cell RNA - U-138 MG [nTPM]":"23.6","Cell RNA - U-2 OS [nTPM]":"27.1","Cell RNA - U-2197 [nTPM]":"39.6","Cell RNA - U-251 MG [nTPM]":"65.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"17.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"16.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"10.7","Brain RNA - basal ganglia [nTPM]":"17.9","Brain RNA - cerebellum [nTPM]":"16.8","Brain RNA - cerebral cortex [nTPM]":"11.5","Brain RNA - hippocampal formation [nTPM]":"9.9","Brain RNA - hypothalamus [nTPM]":"12.9","Brain RNA - medulla oblongata [nTPM]":"27.9","Brain RNA - midbrain [nTPM]":"18.2","Brain RNA - pons [nTPM]":"19.8","Brain RNA - spinal cord [nTPM]":"14.0","Brain RNA - thalamus [nTPM]":"17.3","Brain RNA - white matter [nTPM]":"25.3","Single Cell Type RNA - Adipocytes [nTPM]":"23.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.9","Single Cell Type RNA - Astrocytes [nTPM]":"14.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"2.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"24.7","Single Cell Type RNA - Endothelial cells [nTPM]":"5.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.2","Single Cell Type RNA - Fibroblasts [nTPM]":"9.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.9","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"26.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"1.9","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"20.5","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"6.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"26.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"27.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"21.8","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"26.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.9","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"2.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"5.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"CHSY1","Gene synonym":["CSS1","KIAA0990"],"Ensembl":"ENSG00000131873","Gene description":"Chondroitin sulfate synthase 1","Uniprot":["Q86X52"],"Chromosome":"15","Position":"101175727-101252048","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"216.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.51e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.33e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-3"},"Tissue RNA - adipose tissue [nTPM]":"27.5","Tissue RNA - adrenal gland [nTPM]":"18.6","Tissue RNA - amygdala [nTPM]":"10.3","Tissue RNA - appendix [nTPM]":"18.5","Tissue RNA - basal ganglia [nTPM]":"9.8","Tissue RNA - bone marrow [nTPM]":"23.0","Tissue RNA - breast [nTPM]":"21.7","Tissue RNA - cerebellum [nTPM]":"9.0","Tissue RNA - cerebral cortex [nTPM]":"11.8","Tissue RNA - cervix [nTPM]":"19.5","Tissue RNA - choroid plexus [nTPM]":"14.4","Tissue RNA - colon [nTPM]":"7.7","Tissue RNA - duodenum [nTPM]":"6.0","Tissue RNA - endometrium 1 [nTPM]":"17.3","Tissue RNA - epididymis [nTPM]":"9.5","Tissue RNA - esophagus [nTPM]":"10.8","Tissue RNA - fallopian tube [nTPM]":"14.9","Tissue RNA - gallbladder [nTPM]":"22.7","Tissue RNA - heart muscle [nTPM]":"20.1","Tissue RNA - hippocampal formation [nTPM]":"9.2","Tissue RNA - hypothalamus [nTPM]":"10.3","Tissue RNA - kidney [nTPM]":"13.7","Tissue RNA - liver [nTPM]":"10.0","Tissue RNA - lung [nTPM]":"23.6","Tissue RNA - lymph node [nTPM]":"11.6","Tissue RNA - medulla oblongata [nTPM]":"14.2","Tissue RNA - midbrain [nTPM]":"13.8","Tissue RNA - ovary [nTPM]":"19.7","Tissue RNA - pancreas [nTPM]":"7.3","Tissue RNA - parathyroid gland [nTPM]":"7.4","Tissue RNA - pituitary gland [nTPM]":"8.5","Tissue RNA - placenta [nTPM]":"46.7","Tissue RNA - pons [nTPM]":"11.9","Tissue RNA - prostate [nTPM]":"14.4","Tissue RNA - rectum [nTPM]":"8.2","Tissue RNA - retina [nTPM]":"7.0","Tissue RNA - salivary gland [nTPM]":"10.1","Tissue RNA - seminal vesicle [nTPM]":"11.4","Tissue RNA - skeletal muscle [nTPM]":"6.5","Tissue RNA - skin 1 [nTPM]":"15.0","Tissue RNA - small intestine [nTPM]":"7.7","Tissue RNA - smooth muscle [nTPM]":"20.0","Tissue RNA - spinal cord [nTPM]":"11.5","Tissue RNA - spleen [nTPM]":"13.9","Tissue RNA - stomach 1 [nTPM]":"10.4","Tissue RNA - testis [nTPM]":"8.7","Tissue RNA - thalamus [nTPM]":"12.5","Tissue RNA - thymus [nTPM]":"10.5","Tissue RNA - thyroid gland [nTPM]":"10.0","Tissue RNA - tongue [nTPM]":"7.4","Tissue RNA - tonsil [nTPM]":"10.3","Tissue RNA - urinary bladder [nTPM]":"34.8","Tissue RNA - vagina [nTPM]":"14.0","Tissue RNA - white matter [nTPM]":"9.8","Cell RNA - A-431 [nTPM]":"9.1","Cell RNA - A549 [nTPM]":"11.2","Cell RNA - AF22 [nTPM]":"36.8","Cell RNA - AN3-CA [nTPM]":"18.7","Cell RNA - ASC diff [nTPM]":"18.9","Cell RNA - ASC TERT1 [nTPM]":"25.0","Cell RNA - BEWO [nTPM]":"24.5","Cell RNA - BJ [nTPM]":"21.8","Cell RNA - BJ hTERT+ [nTPM]":"19.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"25.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"26.2","Cell RNA - CACO-2 [nTPM]":"9.7","Cell RNA - CAPAN-2 [nTPM]":"7.1","Cell RNA - Daudi [nTPM]":"22.0","Cell RNA - EFO-21 [nTPM]":"12.7","Cell RNA - fHDF\/TERT166 [nTPM]":"36.3","Cell RNA - GAMG [nTPM]":"16.8","Cell RNA - HaCaT [nTPM]":"24.7","Cell RNA - HAP1 [nTPM]":"24.5","Cell RNA - HBEC3-KT [nTPM]":"27.7","Cell RNA - HBF TERT88 [nTPM]":"28.2","Cell RNA - HDLM-2 [nTPM]":"24.6","Cell RNA - HEK 293 [nTPM]":"12.4","Cell RNA - HEL [nTPM]":"43.4","Cell RNA - HeLa [nTPM]":"12.2","Cell RNA - Hep G2 [nTPM]":"11.4","Cell RNA - HHSteC [nTPM]":"23.3","Cell RNA - HL-60 [nTPM]":"66.9","Cell RNA - HMC-1 [nTPM]":"42.9","Cell RNA - HSkMC [nTPM]":"23.2","Cell RNA - hTCEpi [nTPM]":"22.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.3","Cell RNA - hTERT-HME1 [nTPM]":"20.1","Cell RNA - hTERT-RPE1 [nTPM]":"29.3","Cell RNA - HUVEC TERT2 [nTPM]":"30.8","Cell RNA - JURKAT [nTPM]":"9.7","Cell RNA - K-562 [nTPM]":"16.2","Cell RNA - Karpas-707 [nTPM]":"216.3","Cell RNA - LHCN-M2 [nTPM]":"19.7","Cell RNA - MCF7 [nTPM]":"7.9","Cell RNA - MOLT-4 [nTPM]":"9.2","Cell RNA - NB-4 [nTPM]":"46.3","Cell RNA - NTERA-2 [nTPM]":"42.5","Cell RNA - OE19 [nTPM]":"17.7","Cell RNA - PC-3 [nTPM]":"7.9","Cell RNA - REH [nTPM]":"20.6","Cell RNA - RH-30 [nTPM]":"36.9","Cell RNA - RPMI-8226 [nTPM]":"32.8","Cell RNA - RPTEC TERT1 [nTPM]":"18.1","Cell RNA - RT4 [nTPM]":"17.7","Cell RNA - SCLC-21H [nTPM]":"6.4","Cell RNA - SH-SY5Y [nTPM]":"34.6","Cell RNA - SiHa [nTPM]":"23.0","Cell RNA - SK-BR-3 [nTPM]":"11.1","Cell RNA - SK-MEL-30 [nTPM]":"40.8","Cell RNA - SuSa [nTPM]":"29.8","Cell RNA - T-47d [nTPM]":"12.6","Cell RNA - THP-1 [nTPM]":"81.6","Cell RNA - TIME [nTPM]":"26.2","Cell RNA - U-138 MG [nTPM]":"41.9","Cell RNA - U-2 OS [nTPM]":"24.1","Cell RNA - U-2197 [nTPM]":"20.0","Cell RNA - U-251 MG [nTPM]":"46.5","Cell RNA - U-266\/70 [nTPM]":"38.2","Cell RNA - U-266\/84 [nTPM]":"94.5","Cell RNA - U-698 [nTPM]":"12.7","Cell RNA - U-87 MG [nTPM]":"32.5","Cell RNA - U-937 [nTPM]":"62.2","Cell RNA - WM-115 [nTPM]":"32.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"2.9","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"1.7","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.6","Blood RNA - myeloid DC [nTPM]":"0.8","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"1.0","Blood RNA - neutrophil [nTPM]":"4.9","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"1.8","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"10.3","Brain RNA - basal ganglia [nTPM]":"9.8","Brain RNA - cerebellum [nTPM]":"9.0","Brain RNA - cerebral cortex [nTPM]":"11.8","Brain RNA - hippocampal formation [nTPM]":"9.2","Brain RNA - hypothalamus [nTPM]":"10.3","Brain RNA - medulla oblongata [nTPM]":"14.2","Brain RNA - midbrain [nTPM]":"13.8","Brain RNA - pons [nTPM]":"11.9","Brain RNA - spinal cord [nTPM]":"11.5","Brain RNA - thalamus [nTPM]":"12.5","Brain RNA - white matter [nTPM]":"9.8","Single Cell Type RNA - Adipocytes [nTPM]":"55.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.7","Single Cell Type RNA - Astrocytes [nTPM]":"27.7","Single Cell Type RNA - B-cells [nTPM]":"11.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"57.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"20.5","Single Cell Type RNA - Bipolar cells [nTPM]":"10.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"41.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"29.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"9.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.1","Single Cell Type RNA - dendritic cells [nTPM]":"14.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"33.4","Single Cell Type RNA - Endothelial cells [nTPM]":"45.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"12.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"34.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"28.8","Single Cell Type RNA - Fibroblasts [nTPM]":"40.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.8","Single Cell Type RNA - granulocytes [nTPM]":"25.9","Single Cell Type RNA - Granulosa cells [nTPM]":"51.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"60.0","Single Cell Type RNA - Hepatocytes [nTPM]":"5.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.6","Single Cell Type RNA - Horizontal cells [nTPM]":"38.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"36.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.6","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"17.8","Single Cell Type RNA - Langerhans cells [nTPM]":"37.1","Single Cell Type RNA - Late spermatids [nTPM]":"2.5","Single Cell Type RNA - Leydig cells [nTPM]":"55.0","Single Cell Type RNA - Macrophages [nTPM]":"41.2","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"59.0","Single Cell Type RNA - monocytes [nTPM]":"10.2","Single Cell Type RNA - Muller glia cells [nTPM]":"9.2","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"21.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"24.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.5","Single Cell Type RNA - Paneth cells [nTPM]":"2.5","Single Cell Type RNA - Peritubular cells [nTPM]":"47.0","Single Cell Type RNA - Plasma cells [nTPM]":"9.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.5","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"47.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"53.5","Single Cell Type RNA - Spermatocytes [nTPM]":"3.9","Single Cell Type RNA - Spermatogonia [nTPM]":"7.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"62.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"13.8","Single Cell Type RNA - T-cells [nTPM]":"15.2","Single Cell Type RNA - Theca cells [nTPM]":"23.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.9","Single Cell Type RNA - Urothelial cells [nTPM]":"10.2"},{"Gene":"CHUK","Gene synonym":["IkBKA","IKK-alpha","IKK1","IKKA","NFKBIKA","TCF16"],"Ensembl":"ENSG00000213341","Gene description":"Component of inhibitor of nuclear factor kappa B kinase complex","Uniprot":["O15111"],"Chromosome":"10","Position":"100188300-100229596","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001402","CAB004240","CAB018564"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB004240":"AB_627784","CAB018564":"AB_649197","HPA001402":"AB_1079125"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.61e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.27e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Tissue RNA - adipose tissue [nTPM]":"13.5","Tissue RNA - adrenal gland [nTPM]":"10.3","Tissue RNA - amygdala [nTPM]":"6.6","Tissue RNA - appendix [nTPM]":"11.7","Tissue RNA - basal ganglia [nTPM]":"7.6","Tissue RNA - bone marrow [nTPM]":"19.6","Tissue RNA - breast [nTPM]":"10.8","Tissue RNA - cerebellum [nTPM]":"7.1","Tissue RNA - cerebral cortex [nTPM]":"8.3","Tissue RNA - cervix [nTPM]":"8.4","Tissue RNA - choroid plexus [nTPM]":"8.3","Tissue RNA - colon [nTPM]":"11.9","Tissue RNA - duodenum [nTPM]":"12.8","Tissue RNA - endometrium 1 [nTPM]":"8.8","Tissue RNA - epididymis [nTPM]":"9.1","Tissue RNA - esophagus [nTPM]":"9.7","Tissue RNA - fallopian tube [nTPM]":"7.5","Tissue RNA - gallbladder [nTPM]":"9.0","Tissue RNA - heart muscle [nTPM]":"6.8","Tissue RNA - hippocampal formation [nTPM]":"6.4","Tissue RNA - hypothalamus [nTPM]":"9.2","Tissue RNA - kidney [nTPM]":"21.0","Tissue RNA - liver [nTPM]":"17.0","Tissue RNA - lung [nTPM]":"10.2","Tissue RNA - lymph node [nTPM]":"12.7","Tissue RNA - medulla oblongata [nTPM]":"7.3","Tissue RNA - midbrain [nTPM]":"7.5","Tissue RNA - ovary [nTPM]":"5.6","Tissue RNA - pancreas [nTPM]":"11.5","Tissue RNA - parathyroid gland [nTPM]":"14.0","Tissue RNA - pituitary gland [nTPM]":"6.5","Tissue RNA - placenta [nTPM]":"10.5","Tissue RNA - pons [nTPM]":"7.6","Tissue RNA - prostate [nTPM]":"9.6","Tissue RNA - rectum [nTPM]":"13.3","Tissue RNA - retina [nTPM]":"8.0","Tissue RNA - salivary gland [nTPM]":"8.8","Tissue RNA - seminal vesicle [nTPM]":"9.0","Tissue RNA - skeletal muscle [nTPM]":"14.2","Tissue RNA - skin 1 [nTPM]":"6.9","Tissue RNA - small intestine [nTPM]":"10.8","Tissue RNA - smooth muscle [nTPM]":"11.8","Tissue RNA - spinal cord [nTPM]":"7.7","Tissue RNA - spleen [nTPM]":"9.9","Tissue RNA - stomach 1 [nTPM]":"11.2","Tissue RNA - testis [nTPM]":"8.3","Tissue RNA - thalamus [nTPM]":"8.7","Tissue RNA - thymus [nTPM]":"14.3","Tissue RNA - thyroid gland [nTPM]":"11.1","Tissue RNA - tongue [nTPM]":"11.7","Tissue RNA - tonsil [nTPM]":"12.6","Tissue RNA - urinary bladder [nTPM]":"13.6","Tissue RNA - vagina [nTPM]":"6.4","Tissue RNA - white matter [nTPM]":"8.7","Cell RNA - A-431 [nTPM]":"27.7","Cell RNA - A549 [nTPM]":"22.9","Cell RNA - AF22 [nTPM]":"23.0","Cell RNA - AN3-CA [nTPM]":"34.4","Cell RNA - ASC diff [nTPM]":"21.6","Cell RNA - ASC TERT1 [nTPM]":"19.3","Cell RNA - BEWO [nTPM]":"17.6","Cell RNA - BJ [nTPM]":"34.3","Cell RNA - BJ hTERT+ [nTPM]":"33.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"31.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"38.0","Cell RNA - CACO-2 [nTPM]":"25.9","Cell RNA - CAPAN-2 [nTPM]":"15.9","Cell RNA - Daudi [nTPM]":"37.2","Cell RNA - EFO-21 [nTPM]":"19.7","Cell RNA - fHDF\/TERT166 [nTPM]":"23.5","Cell RNA - GAMG [nTPM]":"21.8","Cell RNA - HaCaT [nTPM]":"26.7","Cell RNA - HAP1 [nTPM]":"38.7","Cell RNA - HBEC3-KT [nTPM]":"18.2","Cell RNA - HBF TERT88 [nTPM]":"34.9","Cell RNA - HDLM-2 [nTPM]":"39.8","Cell RNA - HEK 293 [nTPM]":"33.5","Cell RNA - HEL [nTPM]":"24.7","Cell RNA - HeLa [nTPM]":"18.0","Cell RNA - Hep G2 [nTPM]":"28.7","Cell RNA - HHSteC [nTPM]":"18.4","Cell RNA - HL-60 [nTPM]":"46.2","Cell RNA - HMC-1 [nTPM]":"34.8","Cell RNA - HSkMC [nTPM]":"15.5","Cell RNA - hTCEpi [nTPM]":"19.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"36.2","Cell RNA - hTERT-HME1 [nTPM]":"35.0","Cell RNA - hTERT-RPE1 [nTPM]":"21.8","Cell RNA - HUVEC TERT2 [nTPM]":"22.7","Cell RNA - JURKAT [nTPM]":"30.1","Cell RNA - K-562 [nTPM]":"28.5","Cell RNA - Karpas-707 [nTPM]":"29.9","Cell RNA - LHCN-M2 [nTPM]":"34.6","Cell RNA - MCF7 [nTPM]":"16.7","Cell RNA - MOLT-4 [nTPM]":"36.9","Cell RNA - NB-4 [nTPM]":"28.4","Cell RNA - NTERA-2 [nTPM]":"15.0","Cell RNA - OE19 [nTPM]":"21.8","Cell RNA - PC-3 [nTPM]":"16.5","Cell RNA - REH [nTPM]":"23.7","Cell RNA - RH-30 [nTPM]":"25.5","Cell RNA - RPMI-8226 [nTPM]":"17.0","Cell RNA - RPTEC TERT1 [nTPM]":"19.9","Cell RNA - RT4 [nTPM]":"17.6","Cell RNA - SCLC-21H [nTPM]":"13.7","Cell RNA - SH-SY5Y [nTPM]":"20.3","Cell RNA - SiHa [nTPM]":"18.6","Cell RNA - SK-BR-3 [nTPM]":"14.2","Cell RNA - SK-MEL-30 [nTPM]":"30.9","Cell RNA - SuSa [nTPM]":"18.0","Cell RNA - T-47d [nTPM]":"28.5","Cell RNA - THP-1 [nTPM]":"27.8","Cell RNA - TIME [nTPM]":"23.9","Cell RNA - U-138 MG [nTPM]":"19.6","Cell RNA - U-2 OS [nTPM]":"21.9","Cell RNA - U-2197 [nTPM]":"21.5","Cell RNA - U-251 MG [nTPM]":"39.7","Cell RNA - U-266\/70 [nTPM]":"34.9","Cell RNA - U-266\/84 [nTPM]":"33.7","Cell RNA - U-698 [nTPM]":"35.7","Cell RNA - U-87 MG [nTPM]":"21.3","Cell RNA - U-937 [nTPM]":"36.9","Cell RNA - WM-115 [nTPM]":"15.8","Blood RNA - basophil [nTPM]":"1.0","Blood RNA - classical monocyte [nTPM]":"1.2","Blood RNA - eosinophil [nTPM]":"2.1","Blood RNA - gdT-cell [nTPM]":"0.9","Blood RNA - intermediate monocyte [nTPM]":"1.9","Blood RNA - MAIT T-cell [nTPM]":"1.5","Blood RNA - memory B-cell [nTPM]":"1.6","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.6","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"2.8","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"6.6","Brain RNA - basal ganglia [nTPM]":"7.6","Brain RNA - cerebellum [nTPM]":"7.1","Brain RNA - cerebral cortex [nTPM]":"8.3","Brain RNA - hippocampal formation [nTPM]":"6.4","Brain RNA - hypothalamus [nTPM]":"9.2","Brain RNA - medulla oblongata [nTPM]":"7.3","Brain RNA - midbrain [nTPM]":"7.5","Brain RNA - pons [nTPM]":"7.6","Brain RNA - spinal cord [nTPM]":"7.7","Brain RNA - thalamus [nTPM]":"8.7","Brain RNA - white matter [nTPM]":"8.7","Single Cell Type RNA - Adipocytes [nTPM]":"11.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.5","Single Cell Type RNA - Astrocytes [nTPM]":"17.9","Single Cell Type RNA - B-cells [nTPM]":"10.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"19.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"6.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"5.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.5","Single Cell Type RNA - dendritic cells [nTPM]":"14.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"7.1","Single Cell Type RNA - Early spermatids [nTPM]":"7.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.6","Single Cell Type RNA - Endothelial cells [nTPM]":"8.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"12.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.8","Single Cell Type RNA - Fibroblasts [nTPM]":"6.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.7","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"6.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.1","Single Cell Type RNA - Hepatocytes [nTPM]":"14.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.6","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.0","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"16.9","Single Cell Type RNA - Langerhans cells [nTPM]":"12.7","Single Cell Type RNA - Late spermatids [nTPM]":"8.0","Single Cell Type RNA - Leydig cells [nTPM]":"6.2","Single Cell Type RNA - Macrophages [nTPM]":"11.7","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"15.6","Single Cell Type RNA - Muller glia cells [nTPM]":"4.5","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"27.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.4","Single Cell Type RNA - Paneth cells [nTPM]":"6.0","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"18.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"20.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.0","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.0","Single Cell Type RNA - Spermatocytes [nTPM]":"16.4","Single Cell Type RNA - Spermatogonia [nTPM]":"12.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"19.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"13.8","Single Cell Type RNA - T-cells [nTPM]":"11.1","Single Cell Type RNA - Theca cells [nTPM]":"10.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.6","Single Cell Type RNA - Urothelial cells [nTPM]":"10.6"},{"Gene":"CIB1","Gene synonym":["CIB","KIP","SIP2-28"],"Ensembl":"ENSG00000185043","Gene description":"Calcium and integrin binding 1","Uniprot":["Q99828"],"Chromosome":"15","Position":"90229975-90234047","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Angiogenesis","Apoptosis","Cell adhesion","Cell cycle","Cell division","Differentiation","Spermatogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"1385.8","Respiratory ciliated cells":"1103.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB012991","HPA042413","HPA048825"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB012991":"AB_2533205","HPA042413":"AB_2732498","HPA048825":"AB_2680533"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.26e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.29e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Tissue RNA - adipose tissue [nTPM]":"65.6","Tissue RNA - adrenal gland [nTPM]":"163.6","Tissue RNA - amygdala [nTPM]":"65.4","Tissue RNA - appendix [nTPM]":"79.7","Tissue RNA - basal ganglia [nTPM]":"69.2","Tissue RNA - bone marrow [nTPM]":"205.5","Tissue RNA - breast [nTPM]":"67.4","Tissue RNA - cerebellum [nTPM]":"67.8","Tissue RNA - cerebral cortex [nTPM]":"76.5","Tissue RNA - cervix [nTPM]":"93.8","Tissue RNA - choroid plexus [nTPM]":"96.7","Tissue RNA - colon [nTPM]":"147.9","Tissue RNA - duodenum [nTPM]":"130.1","Tissue RNA - endometrium 1 [nTPM]":"44.6","Tissue RNA - epididymis [nTPM]":"88.1","Tissue RNA - esophagus [nTPM]":"127.3","Tissue RNA - fallopian tube [nTPM]":"146.6","Tissue RNA - gallbladder [nTPM]":"77.4","Tissue RNA - heart muscle [nTPM]":"101.9","Tissue RNA - hippocampal formation [nTPM]":"62.7","Tissue RNA - hypothalamus [nTPM]":"68.8","Tissue RNA - kidney [nTPM]":"220.1","Tissue RNA - liver [nTPM]":"195.7","Tissue RNA - lung [nTPM]":"86.7","Tissue RNA - lymph node [nTPM]":"97.0","Tissue RNA - medulla oblongata [nTPM]":"70.1","Tissue RNA - midbrain [nTPM]":"70.3","Tissue RNA - ovary [nTPM]":"43.9","Tissue RNA - pancreas [nTPM]":"214.1","Tissue RNA - parathyroid gland [nTPM]":"98.3","Tissue RNA - pituitary gland [nTPM]":"93.0","Tissue RNA - placenta [nTPM]":"38.0","Tissue RNA - pons [nTPM]":"68.7","Tissue RNA - prostate [nTPM]":"127.6","Tissue RNA - rectum [nTPM]":"138.1","Tissue RNA - retina [nTPM]":"29.1","Tissue RNA - salivary gland [nTPM]":"116.6","Tissue RNA - seminal vesicle [nTPM]":"72.7","Tissue RNA - skeletal muscle [nTPM]":"58.8","Tissue RNA - skin 1 [nTPM]":"40.4","Tissue RNA - small intestine [nTPM]":"128.5","Tissue RNA - smooth muscle [nTPM]":"45.3","Tissue RNA - spinal cord [nTPM]":"69.3","Tissue RNA - spleen [nTPM]":"117.0","Tissue RNA - stomach 1 [nTPM]":"99.3","Tissue RNA - testis [nTPM]":"113.8","Tissue RNA - thalamus [nTPM]":"69.2","Tissue RNA - thymus [nTPM]":"64.4","Tissue RNA - thyroid gland [nTPM]":"89.1","Tissue RNA - tongue [nTPM]":"42.3","Tissue RNA - tonsil [nTPM]":"120.9","Tissue RNA - urinary bladder [nTPM]":"93.7","Tissue RNA - vagina [nTPM]":"68.3","Tissue RNA - white matter [nTPM]":"69.3","Cell RNA - A-431 [nTPM]":"119.5","Cell RNA - A549 [nTPM]":"261.4","Cell RNA - AF22 [nTPM]":"23.8","Cell RNA - AN3-CA [nTPM]":"83.7","Cell RNA - ASC diff [nTPM]":"98.7","Cell RNA - ASC TERT1 [nTPM]":"102.7","Cell RNA - BEWO [nTPM]":"38.9","Cell RNA - BJ [nTPM]":"123.8","Cell RNA - BJ hTERT+ [nTPM]":"107.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"99.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"87.2","Cell RNA - CACO-2 [nTPM]":"104.7","Cell RNA - CAPAN-2 [nTPM]":"207.4","Cell RNA - Daudi [nTPM]":"34.7","Cell RNA - EFO-21 [nTPM]":"129.7","Cell RNA - fHDF\/TERT166 [nTPM]":"144.0","Cell RNA - GAMG [nTPM]":"125.7","Cell RNA - HaCaT [nTPM]":"124.2","Cell RNA - HAP1 [nTPM]":"48.0","Cell RNA - HBEC3-KT [nTPM]":"141.8","Cell RNA - HBF TERT88 [nTPM]":"54.0","Cell RNA - HDLM-2 [nTPM]":"81.9","Cell RNA - HEK 293 [nTPM]":"114.2","Cell RNA - HEL [nTPM]":"77.5","Cell RNA - HeLa [nTPM]":"182.3","Cell RNA - Hep G2 [nTPM]":"175.9","Cell RNA - HHSteC [nTPM]":"96.2","Cell RNA - HL-60 [nTPM]":"155.2","Cell RNA - HMC-1 [nTPM]":"71.4","Cell RNA - HSkMC [nTPM]":"72.2","Cell RNA - hTCEpi [nTPM]":"84.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"91.9","Cell RNA - hTERT-HME1 [nTPM]":"64.6","Cell RNA - hTERT-RPE1 [nTPM]":"113.7","Cell RNA - HUVEC TERT2 [nTPM]":"129.1","Cell RNA - JURKAT [nTPM]":"83.7","Cell RNA - K-562 [nTPM]":"105.8","Cell RNA - Karpas-707 [nTPM]":"53.5","Cell RNA - LHCN-M2 [nTPM]":"76.4","Cell RNA - MCF7 [nTPM]":"233.3","Cell RNA - MOLT-4 [nTPM]":"118.4","Cell RNA - NB-4 [nTPM]":"179.4","Cell RNA - NTERA-2 [nTPM]":"36.7","Cell RNA - OE19 [nTPM]":"223.9","Cell RNA - PC-3 [nTPM]":"134.0","Cell RNA - REH [nTPM]":"66.1","Cell RNA - RH-30 [nTPM]":"62.8","Cell RNA - RPMI-8226 [nTPM]":"139.7","Cell RNA - RPTEC TERT1 [nTPM]":"256.1","Cell RNA - RT4 [nTPM]":"199.4","Cell RNA - SCLC-21H [nTPM]":"18.7","Cell RNA - SH-SY5Y [nTPM]":"22.8","Cell RNA - SiHa [nTPM]":"168.7","Cell RNA - SK-BR-3 [nTPM]":"136.5","Cell RNA - SK-MEL-30 [nTPM]":"135.7","Cell RNA - SuSa [nTPM]":"41.5","Cell RNA - T-47d [nTPM]":"105.3","Cell RNA - THP-1 [nTPM]":"93.3","Cell RNA - TIME [nTPM]":"81.7","Cell RNA - U-138 MG [nTPM]":"109.6","Cell RNA - U-2 OS [nTPM]":"77.0","Cell RNA - U-2197 [nTPM]":"132.0","Cell RNA - U-251 MG [nTPM]":"153.2","Cell RNA - U-266\/70 [nTPM]":"73.0","Cell RNA - U-266\/84 [nTPM]":"122.0","Cell RNA - U-698 [nTPM]":"40.3","Cell RNA - U-87 MG [nTPM]":"176.1","Cell RNA - U-937 [nTPM]":"174.9","Cell RNA - WM-115 [nTPM]":"47.8","Blood RNA - basophil [nTPM]":"168.9","Blood RNA - classical monocyte [nTPM]":"201.8","Blood RNA - eosinophil [nTPM]":"271.3","Blood RNA - gdT-cell [nTPM]":"226.9","Blood RNA - intermediate monocyte [nTPM]":"248.9","Blood RNA - MAIT T-cell [nTPM]":"188.0","Blood RNA - memory B-cell [nTPM]":"476.4","Blood RNA - memory CD4 T-cell [nTPM]":"269.9","Blood RNA - memory CD8 T-cell [nTPM]":"249.4","Blood RNA - myeloid DC [nTPM]":"224.4","Blood RNA - naive B-cell [nTPM]":"418.0","Blood RNA - naive CD4 T-cell [nTPM]":"221.5","Blood RNA - naive CD8 T-cell [nTPM]":"218.0","Blood RNA - neutrophil [nTPM]":"118.2","Blood RNA - NK-cell [nTPM]":"205.7","Blood RNA - non-classical monocyte [nTPM]":"230.0","Blood RNA - plasmacytoid DC [nTPM]":"149.7","Blood RNA - T-reg [nTPM]":"245.8","Blood RNA - total PBMC [nTPM]":"399.6","Brain RNA - amygdala [nTPM]":"65.4","Brain RNA - basal ganglia [nTPM]":"69.2","Brain RNA - cerebellum [nTPM]":"67.8","Brain RNA - cerebral cortex [nTPM]":"76.5","Brain RNA - hippocampal formation [nTPM]":"62.7","Brain RNA - hypothalamus [nTPM]":"68.8","Brain RNA - medulla oblongata [nTPM]":"70.1","Brain RNA - midbrain [nTPM]":"70.3","Brain RNA - pons [nTPM]":"68.7","Brain RNA - spinal cord [nTPM]":"69.3","Brain RNA - thalamus [nTPM]":"69.2","Brain RNA - white matter [nTPM]":"69.3","Single Cell Type RNA - Adipocytes [nTPM]":"77.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"89.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"104.2","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"203.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"85.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"253.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"520.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"84.8","Single Cell Type RNA - Bipolar cells [nTPM]":"12.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"152.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"118.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"86.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"128.7","Single Cell Type RNA - Club cells [nTPM]":"469.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"183.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"106.7","Single Cell Type RNA - dendritic cells [nTPM]":"198.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"670.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"453.9","Single Cell Type RNA - Ductal cells [nTPM]":"372.1","Single Cell Type RNA - Early spermatids [nTPM]":"380.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"480.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"101.3","Single Cell Type RNA - Endothelial cells [nTPM]":"83.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"97.1","Single Cell Type RNA - Erythroid cells [nTPM]":"62.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"662.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"117.6","Single Cell Type RNA - Fibroblasts [nTPM]":"96.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"149.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"222.8","Single Cell Type RNA - granulocytes [nTPM]":"138.8","Single Cell Type RNA - Granulosa cells [nTPM]":"66.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"79.6","Single Cell Type RNA - Hepatocytes [nTPM]":"230.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"209.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"379.5","Single Cell Type RNA - Ionocytes [nTPM]":"463.9","Single Cell Type RNA - Kupffer cells [nTPM]":"102.5","Single Cell Type RNA - Langerhans cells [nTPM]":"148.0","Single Cell Type RNA - Late spermatids [nTPM]":"1385.8","Single Cell Type RNA - Leydig cells [nTPM]":"105.3","Single Cell Type RNA - Macrophages [nTPM]":"180.5","Single Cell Type RNA - Melanocytes [nTPM]":"128.1","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"187.5","Single Cell Type RNA - Muller glia cells [nTPM]":"138.4","Single Cell Type RNA - NK-cells [nTPM]":"184.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"620.2","Single Cell Type RNA - Paneth cells [nTPM]":"794.2","Single Cell Type RNA - Peritubular cells [nTPM]":"92.6","Single Cell Type RNA - Plasma cells [nTPM]":"88.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"699.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"661.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"668.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1103.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"25.5","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"62.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"140.4","Single Cell Type RNA - Spermatocytes [nTPM]":"160.3","Single Cell Type RNA - Spermatogonia [nTPM]":"69.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"218.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"67.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"66.1","Single Cell Type RNA - T-cells [nTPM]":"227.5","Single Cell Type RNA - Theca cells [nTPM]":"91.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"315.5","Single Cell Type RNA - Urothelial cells [nTPM]":"577.8"},{"Gene":"CIITA","Gene synonym":["C2TA","MHC2TA","NLRA"],"Ensembl":"ENSG00000179583","Gene description":"Class II major histocompatibility complex transactivator","Uniprot":["P33076"],"Chromosome":"16","Position":"10866222-10943021","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","Acyltransferase","Kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"57.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"48.8","Langerhans cells":"51.8","Macrophages":"43.8","Microglial cells":"42.2","monocytes":"51.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"classical monocyte":"29.1","eosinophil":"17.5","intermediate monocyte":"23.5","memory B-cell":"47.3","myeloid DC":"46.2","naive B-cell":"63.3","non-classical monocyte":"29.0","plasmacytoid DC":"48.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"51.1","REH":"89.5","U-266\/70":"18.0","U-698":"25.8"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016084","HPA054757"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 14: REH - Unknown function","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB016084":"AB_627261","HPA054757":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.4","Tissue RNA - adrenal gland [nTPM]":"6.5","Tissue RNA - amygdala [nTPM]":"6.4","Tissue RNA - appendix [nTPM]":"39.2","Tissue RNA - basal ganglia [nTPM]":"5.9","Tissue RNA - bone marrow [nTPM]":"9.2","Tissue RNA - breast [nTPM]":"7.8","Tissue RNA - cerebellum [nTPM]":"7.3","Tissue RNA - cerebral cortex [nTPM]":"7.9","Tissue RNA - cervix [nTPM]":"10.7","Tissue RNA - choroid plexus [nTPM]":"8.9","Tissue RNA - colon [nTPM]":"6.7","Tissue RNA - duodenum [nTPM]":"20.5","Tissue RNA - endometrium 1 [nTPM]":"7.3","Tissue RNA - epididymis [nTPM]":"2.6","Tissue RNA - esophagus [nTPM]":"5.5","Tissue RNA - fallopian tube [nTPM]":"7.4","Tissue RNA - gallbladder [nTPM]":"15.0","Tissue RNA - heart muscle [nTPM]":"5.4","Tissue RNA - hippocampal formation [nTPM]":"5.4","Tissue RNA - hypothalamus [nTPM]":"11.5","Tissue RNA - kidney [nTPM]":"7.2","Tissue RNA - liver [nTPM]":"4.7","Tissue RNA - lung [nTPM]":"24.1","Tissue RNA - lymph node [nTPM]":"57.3","Tissue RNA - medulla oblongata [nTPM]":"15.0","Tissue RNA - midbrain [nTPM]":"8.3","Tissue RNA - ovary [nTPM]":"3.6","Tissue RNA - pancreas [nTPM]":"3.9","Tissue RNA - parathyroid gland [nTPM]":"2.6","Tissue RNA - pituitary gland [nTPM]":"3.0","Tissue RNA - placenta [nTPM]":"2.6","Tissue RNA - pons [nTPM]":"11.9","Tissue RNA - prostate [nTPM]":"4.8","Tissue RNA - rectum [nTPM]":"8.2","Tissue RNA - retina [nTPM]":"1.4","Tissue RNA - salivary gland [nTPM]":"12.1","Tissue RNA - seminal vesicle [nTPM]":"6.9","Tissue RNA - skeletal muscle [nTPM]":"5.0","Tissue RNA - skin 1 [nTPM]":"8.7","Tissue RNA - small intestine [nTPM]":"24.8","Tissue RNA - smooth muscle [nTPM]":"7.3","Tissue RNA - spinal cord [nTPM]":"11.5","Tissue RNA - spleen [nTPM]":"51.2","Tissue RNA - stomach 1 [nTPM]":"12.9","Tissue RNA - testis [nTPM]":"2.1","Tissue RNA - thalamus [nTPM]":"13.0","Tissue RNA - thymus [nTPM]":"15.9","Tissue RNA - thyroid gland [nTPM]":"5.2","Tissue RNA - tongue [nTPM]":"2.4","Tissue RNA - tonsil [nTPM]":"57.0","Tissue RNA - urinary bladder [nTPM]":"9.0","Tissue RNA - vagina [nTPM]":"4.1","Tissue RNA - white matter [nTPM]":"16.4","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"0.7","Cell RNA - AN3-CA [nTPM]":"0.6","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"0.6","Cell RNA - CAPAN-2 [nTPM]":"12.0","Cell RNA - Daudi [nTPM]":"11.2","Cell RNA - EFO-21 [nTPM]":"1.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"1.7","Cell RNA - HaCaT [nTPM]":"1.8","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"51.1","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"6.3","Cell RNA - HeLa [nTPM]":"2.6","Cell RNA - Hep G2 [nTPM]":"1.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.9","Cell RNA - HMC-1 [nTPM]":"0.9","Cell RNA - HSkMC [nTPM]":"2.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"1.8","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.8","Cell RNA - Karpas-707 [nTPM]":"4.1","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.7","Cell RNA - MOLT-4 [nTPM]":"0.6","Cell RNA - NB-4 [nTPM]":"1.0","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.4","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"89.5","Cell RNA - RH-30 [nTPM]":"0.6","Cell RNA - RPMI-8226 [nTPM]":"7.9","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"3.6","Cell RNA - SCLC-21H [nTPM]":"1.8","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"2.1","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"2.1","Cell RNA - SuSa [nTPM]":"0.6","Cell RNA - T-47d [nTPM]":"1.0","Cell RNA - THP-1 [nTPM]":"3.8","Cell RNA - TIME [nTPM]":"0.5","Cell RNA - U-138 MG [nTPM]":"4.3","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"1.2","Cell RNA - U-251 MG [nTPM]":"0.5","Cell RNA - U-266\/70 [nTPM]":"18.0","Cell RNA - U-266\/84 [nTPM]":"1.4","Cell RNA - U-698 [nTPM]":"25.8","Cell RNA - U-87 MG [nTPM]":"16.0","Cell RNA - U-937 [nTPM]":"1.1","Cell RNA - WM-115 [nTPM]":"14.7","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"29.1","Blood RNA - eosinophil [nTPM]":"17.5","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"23.5","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"47.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"46.2","Blood RNA - naive B-cell [nTPM]":"63.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"6.8","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"29.0","Blood RNA - plasmacytoid DC [nTPM]":"48.3","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"5.4","Brain RNA - amygdala [nTPM]":"6.4","Brain RNA - basal ganglia [nTPM]":"5.9","Brain RNA - cerebellum [nTPM]":"7.3","Brain RNA - cerebral cortex [nTPM]":"7.9","Brain RNA - hippocampal formation [nTPM]":"5.4","Brain RNA - hypothalamus [nTPM]":"11.5","Brain RNA - medulla oblongata [nTPM]":"15.0","Brain RNA - midbrain [nTPM]":"8.3","Brain RNA - pons [nTPM]":"11.9","Brain RNA - spinal cord [nTPM]":"11.5","Brain RNA - thalamus [nTPM]":"13.0","Brain RNA - white matter [nTPM]":"16.4","Single Cell Type RNA - Adipocytes [nTPM]":"14.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"48.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"1.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"17.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"7.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"6.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"1.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.4","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"7.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"16.1","Single Cell Type RNA - Langerhans cells [nTPM]":"51.8","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"43.8","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"42.2","Single Cell Type RNA - monocytes [nTPM]":"51.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"3.0","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.5"},{"Gene":"CILK1","Gene synonym":["ICK","KIAA0936","LCK2","MGC46090","MRK"],"Ensembl":"ENSG00000112144","Gene description":"Ciliogenesis associated kinase 1","Uniprot":["Q9UPZ9"],"Chromosome":"6","Position":"53001279-53061824","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":["Developmental protein","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"11.0","Cytotrophoblasts":"20.6","Extravillous trophoblasts":"33.9","Syncytiotrophoblasts":"58.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000791","HPA001113"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":null,"Antibody RRID":{"HPA000791":"AB_2732392","HPA001113":"AB_1851385"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.9","Tissue RNA - adrenal gland [nTPM]":"17.9","Tissue RNA - amygdala [nTPM]":"10.2","Tissue RNA - appendix [nTPM]":"4.9","Tissue RNA - basal ganglia [nTPM]":"11.0","Tissue RNA - bone marrow [nTPM]":"2.7","Tissue RNA - breast [nTPM]":"10.7","Tissue RNA - cerebellum [nTPM]":"8.4","Tissue RNA - cerebral cortex [nTPM]":"9.7","Tissue RNA - cervix [nTPM]":"8.9","Tissue RNA - choroid plexus [nTPM]":"5.1","Tissue RNA - colon [nTPM]":"8.7","Tissue RNA - duodenum [nTPM]":"9.8","Tissue RNA - endometrium 1 [nTPM]":"8.0","Tissue RNA - epididymis [nTPM]":"5.5","Tissue RNA - esophagus [nTPM]":"8.6","Tissue RNA - fallopian tube [nTPM]":"7.4","Tissue RNA - gallbladder [nTPM]":"6.9","Tissue RNA - heart muscle [nTPM]":"8.5","Tissue RNA - hippocampal formation [nTPM]":"6.8","Tissue RNA - hypothalamus [nTPM]":"7.8","Tissue RNA - kidney [nTPM]":"4.5","Tissue RNA - liver [nTPM]":"7.5","Tissue RNA - lung [nTPM]":"6.3","Tissue RNA - lymph node [nTPM]":"5.2","Tissue RNA - medulla oblongata [nTPM]":"9.4","Tissue RNA - midbrain [nTPM]":"11.6","Tissue RNA - ovary [nTPM]":"9.5","Tissue RNA - pancreas [nTPM]":"5.0","Tissue RNA - parathyroid gland [nTPM]":"7.3","Tissue RNA - pituitary gland [nTPM]":"1.7","Tissue RNA - placenta [nTPM]":"12.1","Tissue RNA - pons [nTPM]":"8.8","Tissue RNA - prostate [nTPM]":"9.9","Tissue RNA - rectum [nTPM]":"10.7","Tissue RNA - retina [nTPM]":"17.4","Tissue RNA - salivary gland [nTPM]":"17.9","Tissue RNA - seminal vesicle [nTPM]":"7.3","Tissue RNA - skeletal muscle [nTPM]":"4.0","Tissue RNA - skin 1 [nTPM]":"8.7","Tissue RNA - small intestine [nTPM]":"10.4","Tissue RNA - smooth muscle [nTPM]":"7.4","Tissue RNA - spinal cord [nTPM]":"8.8","Tissue RNA - spleen [nTPM]":"5.6","Tissue RNA - stomach 1 [nTPM]":"12.9","Tissue RNA - testis [nTPM]":"4.5","Tissue RNA - thalamus [nTPM]":"14.9","Tissue RNA - thymus [nTPM]":"10.1","Tissue RNA - thyroid gland [nTPM]":"6.3","Tissue RNA - tongue [nTPM]":"5.0","Tissue RNA - tonsil [nTPM]":"6.2","Tissue RNA - urinary bladder [nTPM]":"6.5","Tissue RNA - vagina [nTPM]":"5.8","Tissue RNA - white matter [nTPM]":"12.8","Cell RNA - A-431 [nTPM]":"7.8","Cell RNA - A549 [nTPM]":"2.9","Cell RNA - AF22 [nTPM]":"14.6","Cell RNA - AN3-CA [nTPM]":"10.0","Cell RNA - ASC diff [nTPM]":"8.9","Cell RNA - ASC TERT1 [nTPM]":"14.0","Cell RNA - BEWO [nTPM]":"17.0","Cell RNA - BJ [nTPM]":"6.9","Cell RNA - BJ hTERT+ [nTPM]":"12.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.3","Cell RNA - CACO-2 [nTPM]":"4.1","Cell RNA - CAPAN-2 [nTPM]":"2.4","Cell RNA - Daudi [nTPM]":"5.7","Cell RNA - EFO-21 [nTPM]":"4.0","Cell RNA - fHDF\/TERT166 [nTPM]":"21.0","Cell RNA - GAMG [nTPM]":"3.5","Cell RNA - HaCaT [nTPM]":"5.0","Cell RNA - HAP1 [nTPM]":"17.6","Cell RNA - HBEC3-KT [nTPM]":"7.1","Cell RNA - HBF TERT88 [nTPM]":"14.2","Cell RNA - HDLM-2 [nTPM]":"19.9","Cell RNA - HEK 293 [nTPM]":"7.0","Cell RNA - HEL [nTPM]":"4.2","Cell RNA - HeLa [nTPM]":"3.3","Cell RNA - Hep G2 [nTPM]":"22.3","Cell RNA - HHSteC [nTPM]":"4.5","Cell RNA - HL-60 [nTPM]":"5.2","Cell RNA - HMC-1 [nTPM]":"5.4","Cell RNA - HSkMC [nTPM]":"12.5","Cell RNA - hTCEpi [nTPM]":"7.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.6","Cell RNA - hTERT-HME1 [nTPM]":"5.3","Cell RNA - hTERT-RPE1 [nTPM]":"7.7","Cell RNA - HUVEC TERT2 [nTPM]":"10.2","Cell RNA - JURKAT [nTPM]":"12.1","Cell RNA - K-562 [nTPM]":"8.1","Cell RNA - Karpas-707 [nTPM]":"22.6","Cell RNA - LHCN-M2 [nTPM]":"24.9","Cell RNA - MCF7 [nTPM]":"6.7","Cell RNA - MOLT-4 [nTPM]":"5.6","Cell RNA - NB-4 [nTPM]":"6.4","Cell RNA - NTERA-2 [nTPM]":"5.6","Cell RNA - OE19 [nTPM]":"27.0","Cell RNA - PC-3 [nTPM]":"6.3","Cell RNA - REH [nTPM]":"8.8","Cell RNA - RH-30 [nTPM]":"6.5","Cell RNA - RPMI-8226 [nTPM]":"7.5","Cell RNA - RPTEC TERT1 [nTPM]":"4.5","Cell RNA - RT4 [nTPM]":"5.6","Cell RNA - SCLC-21H [nTPM]":"23.6","Cell RNA - SH-SY5Y [nTPM]":"10.6","Cell RNA - SiHa [nTPM]":"6.7","Cell RNA - SK-BR-3 [nTPM]":"16.3","Cell RNA - SK-MEL-30 [nTPM]":"9.6","Cell RNA - SuSa [nTPM]":"14.2","Cell RNA - T-47d [nTPM]":"9.5","Cell RNA - THP-1 [nTPM]":"10.9","Cell RNA - TIME [nTPM]":"8.5","Cell RNA - U-138 MG [nTPM]":"17.2","Cell RNA - U-2 OS [nTPM]":"8.0","Cell RNA - U-2197 [nTPM]":"6.5","Cell RNA - U-251 MG [nTPM]":"17.1","Cell RNA - U-266\/70 [nTPM]":"6.3","Cell RNA - U-266\/84 [nTPM]":"4.8","Cell RNA - U-698 [nTPM]":"2.2","Cell RNA - U-87 MG [nTPM]":"3.5","Cell RNA - U-937 [nTPM]":"5.0","Cell RNA - WM-115 [nTPM]":"8.5","Blood RNA - basophil [nTPM]":"2.8","Blood RNA - classical monocyte [nTPM]":"1.0","Blood RNA - eosinophil [nTPM]":"2.2","Blood RNA - gdT-cell [nTPM]":"1.7","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"1.5","Blood RNA - memory B-cell [nTPM]":"1.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.2","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"1.0","Blood RNA - naive B-cell [nTPM]":"1.5","Blood RNA - naive CD4 T-cell [nTPM]":"1.4","Blood RNA - naive CD8 T-cell [nTPM]":"1.2","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"1.4","Blood RNA - T-reg [nTPM]":"1.7","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"10.2","Brain RNA - basal ganglia [nTPM]":"11.0","Brain RNA - cerebellum [nTPM]":"8.4","Brain RNA - cerebral cortex [nTPM]":"9.7","Brain RNA - hippocampal formation [nTPM]":"6.8","Brain RNA - hypothalamus [nTPM]":"7.8","Brain RNA - medulla oblongata [nTPM]":"9.4","Brain RNA - midbrain [nTPM]":"11.6","Brain RNA - pons [nTPM]":"8.8","Brain RNA - spinal cord [nTPM]":"8.8","Brain RNA - thalamus [nTPM]":"14.9","Brain RNA - white matter [nTPM]":"12.8","Single Cell Type RNA - Adipocytes [nTPM]":"6.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.6","Single Cell Type RNA - dendritic cells [nTPM]":"5.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"33.9","Single Cell Type RNA - Fibroblasts [nTPM]":"5.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"58.1","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CIT","Gene synonym":["CITK","CRIK","KIAA0949","STK21"],"Ensembl":"ENSG00000122966","Gene description":"Citron rho-interacting serine\/threonine kinase","Uniprot":["O14578"],"Chromosome":"12","Position":"119685791-119877320","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Differentiation","Mitosis","Neurogenesis"],"Molecular function":["Developmental protein","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Primary microcephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"26.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"87.6","Early spermatids":"72.8","Excitatory neurons":"147.0","Inhibitory neurons":"139.8","Oligodendrocyte precursor cells":"82.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019082","HPA048812","HPA075506"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA019082":"AB_1846803","HPA048812":"AB_2680528","HPA075506":"AB_2686752"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.7","Tissue RNA - adrenal gland [nTPM]":"2.2","Tissue RNA - amygdala [nTPM]":"13.5","Tissue RNA - appendix [nTPM]":"1.6","Tissue RNA - basal ganglia [nTPM]":"26.2","Tissue RNA - bone marrow [nTPM]":"6.3","Tissue RNA - breast [nTPM]":"0.6","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"19.9","Tissue RNA - cervix [nTPM]":"0.9","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"2.1","Tissue RNA - duodenum [nTPM]":"1.2","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"2.5","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"0.6","Tissue RNA - hippocampal formation [nTPM]":"15.2","Tissue RNA - hypothalamus [nTPM]":"5.4","Tissue RNA - kidney [nTPM]":"2.5","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"1.8","Tissue RNA - lymph node [nTPM]":"1.5","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"5.0","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"1.6","Tissue RNA - placenta [nTPM]":"1.4","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"2.5","Tissue RNA - retina [nTPM]":"3.4","Tissue RNA - salivary gland [nTPM]":"0.8","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"1.6","Tissue RNA - small intestine [nTPM]":"1.9","Tissue RNA - smooth muscle [nTPM]":"0.9","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"3.0","Tissue RNA - stomach 1 [nTPM]":"2.2","Tissue RNA - testis [nTPM]":"4.8","Tissue RNA - thalamus [nTPM]":"14.2","Tissue RNA - thymus [nTPM]":"6.8","Tissue RNA - thyroid gland [nTPM]":"0.6","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"2.3","Tissue RNA - urinary bladder [nTPM]":"0.5","Tissue RNA - vagina [nTPM]":"1.3","Tissue RNA - white matter [nTPM]":"6.6","Cell RNA - A-431 [nTPM]":"26.2","Cell RNA - A549 [nTPM]":"20.6","Cell RNA - AF22 [nTPM]":"21.7","Cell RNA - AN3-CA [nTPM]":"15.3","Cell RNA - ASC diff [nTPM]":"2.4","Cell RNA - ASC TERT1 [nTPM]":"6.3","Cell RNA - BEWO [nTPM]":"10.4","Cell RNA - BJ [nTPM]":"22.0","Cell RNA - BJ hTERT+ [nTPM]":"19.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.6","Cell RNA - CACO-2 [nTPM]":"14.5","Cell RNA - CAPAN-2 [nTPM]":"10.3","Cell RNA - Daudi [nTPM]":"18.4","Cell RNA - EFO-21 [nTPM]":"10.0","Cell RNA - fHDF\/TERT166 [nTPM]":"14.2","Cell RNA - GAMG [nTPM]":"9.3","Cell RNA - HaCaT [nTPM]":"14.6","Cell RNA - HAP1 [nTPM]":"14.4","Cell RNA - HBEC3-KT [nTPM]":"9.5","Cell RNA - HBF TERT88 [nTPM]":"32.1","Cell RNA - HDLM-2 [nTPM]":"13.6","Cell RNA - HEK 293 [nTPM]":"7.5","Cell RNA - HEL [nTPM]":"25.7","Cell RNA - HeLa [nTPM]":"13.2","Cell RNA - Hep G2 [nTPM]":"7.1","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"12.7","Cell RNA - HMC-1 [nTPM]":"20.6","Cell RNA - HSkMC [nTPM]":"0.9","Cell RNA - hTCEpi [nTPM]":"1.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"23.7","Cell RNA - hTERT-HME1 [nTPM]":"14.8","Cell RNA - hTERT-RPE1 [nTPM]":"7.3","Cell RNA - HUVEC TERT2 [nTPM]":"15.5","Cell RNA - JURKAT [nTPM]":"19.9","Cell RNA - K-562 [nTPM]":"14.5","Cell RNA - Karpas-707 [nTPM]":"15.2","Cell RNA - LHCN-M2 [nTPM]":"19.5","Cell RNA - MCF7 [nTPM]":"12.2","Cell RNA - MOLT-4 [nTPM]":"22.4","Cell RNA - NB-4 [nTPM]":"14.0","Cell RNA - NTERA-2 [nTPM]":"10.4","Cell RNA - OE19 [nTPM]":"8.7","Cell RNA - PC-3 [nTPM]":"12.5","Cell RNA - REH [nTPM]":"19.3","Cell RNA - RH-30 [nTPM]":"39.8","Cell RNA - RPMI-8226 [nTPM]":"6.3","Cell RNA - RPTEC TERT1 [nTPM]":"5.0","Cell RNA - RT4 [nTPM]":"11.1","Cell RNA - SCLC-21H [nTPM]":"15.5","Cell RNA - SH-SY5Y [nTPM]":"8.4","Cell RNA - SiHa [nTPM]":"31.9","Cell RNA - SK-BR-3 [nTPM]":"6.5","Cell RNA - SK-MEL-30 [nTPM]":"16.0","Cell RNA - SuSa [nTPM]":"9.6","Cell RNA - T-47d [nTPM]":"23.2","Cell RNA - THP-1 [nTPM]":"10.6","Cell RNA - TIME [nTPM]":"11.5","Cell RNA - U-138 MG [nTPM]":"21.9","Cell RNA - U-2 OS [nTPM]":"21.4","Cell RNA - U-2197 [nTPM]":"17.2","Cell RNA - U-251 MG [nTPM]":"22.7","Cell RNA - U-266\/70 [nTPM]":"9.9","Cell RNA - U-266\/84 [nTPM]":"12.6","Cell RNA - U-698 [nTPM]":"14.2","Cell RNA - U-87 MG [nTPM]":"16.8","Cell RNA - U-937 [nTPM]":"12.5","Cell RNA - WM-115 [nTPM]":"35.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"13.5","Brain RNA - basal ganglia [nTPM]":"26.2","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"19.9","Brain RNA - hippocampal formation [nTPM]":"15.2","Brain RNA - hypothalamus [nTPM]":"5.4","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"5.0","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"14.2","Brain RNA - white matter [nTPM]":"6.6","Single Cell Type RNA - Adipocytes [nTPM]":"4.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.0","Single Cell Type RNA - Astrocytes [nTPM]":"8.5","Single Cell Type RNA - B-cells [nTPM]":"1.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"8.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"5.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"87.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"72.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.1","Single Cell Type RNA - Endothelial cells [nTPM]":"2.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"12.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"147.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.8","Single Cell Type RNA - Fibroblasts [nTPM]":"2.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.6","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"10.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"139.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.4","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"3.7","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"44.1","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"2.0","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"15.4","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"82.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"4.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.3","Single Cell Type RNA - Spermatocytes [nTPM]":"33.2","Single Cell Type RNA - Spermatogonia [nTPM]":"4.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"2.2","Single Cell Type RNA - Theca cells [nTPM]":"4.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.4","Single Cell Type RNA - Urothelial cells [nTPM]":"1.0"},{"Gene":"CLCC1","Gene synonym":["MCLC"],"Ensembl":"ENSG00000121940","Gene description":"Chloride channel CLIC like 1","Uniprot":["Q96S66"],"Chromosome":"1","Position":"108927361-108963504","Protein class":["Disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":["Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009087","HPA013210"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA009087":"AB_1078532","HPA013210":"AB_1846895"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.33e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-2"},"Tissue RNA - adipose tissue [nTPM]":"14.6","Tissue RNA - adrenal gland [nTPM]":"16.5","Tissue RNA - amygdala [nTPM]":"10.1","Tissue RNA - appendix [nTPM]":"11.4","Tissue RNA - basal ganglia [nTPM]":"14.3","Tissue RNA - bone marrow [nTPM]":"6.1","Tissue RNA - breast [nTPM]":"16.3","Tissue RNA - cerebellum [nTPM]":"10.6","Tissue RNA - cerebral cortex [nTPM]":"11.7","Tissue RNA - cervix [nTPM]":"17.0","Tissue RNA - choroid plexus [nTPM]":"7.8","Tissue RNA - colon [nTPM]":"15.4","Tissue RNA - duodenum [nTPM]":"13.2","Tissue RNA - endometrium 1 [nTPM]":"17.0","Tissue RNA - epididymis [nTPM]":"24.3","Tissue RNA - esophagus [nTPM]":"9.9","Tissue RNA - fallopian tube [nTPM]":"15.1","Tissue RNA - gallbladder [nTPM]":"14.0","Tissue RNA - heart muscle [nTPM]":"18.3","Tissue RNA - hippocampal formation [nTPM]":"10.7","Tissue RNA - hypothalamus [nTPM]":"11.5","Tissue RNA - kidney [nTPM]":"11.0","Tissue RNA - liver [nTPM]":"22.2","Tissue RNA - lung [nTPM]":"13.0","Tissue RNA - lymph node [nTPM]":"10.5","Tissue RNA - medulla oblongata [nTPM]":"12.8","Tissue RNA - midbrain [nTPM]":"10.9","Tissue RNA - ovary [nTPM]":"18.6","Tissue RNA - pancreas [nTPM]":"24.8","Tissue RNA - parathyroid gland [nTPM]":"21.3","Tissue RNA - pituitary gland [nTPM]":"18.3","Tissue RNA - placenta [nTPM]":"17.7","Tissue RNA - pons [nTPM]":"12.1","Tissue RNA - prostate [nTPM]":"20.2","Tissue RNA - rectum [nTPM]":"13.2","Tissue RNA - retina [nTPM]":"11.8","Tissue RNA - salivary gland [nTPM]":"22.3","Tissue RNA - seminal vesicle [nTPM]":"20.0","Tissue RNA - skeletal muscle [nTPM]":"27.2","Tissue RNA - skin 1 [nTPM]":"10.3","Tissue RNA - small intestine [nTPM]":"12.7","Tissue RNA - smooth muscle [nTPM]":"14.9","Tissue RNA - spinal cord [nTPM]":"11.0","Tissue RNA - spleen [nTPM]":"11.5","Tissue RNA - stomach 1 [nTPM]":"16.1","Tissue RNA - testis [nTPM]":"7.6","Tissue RNA - thalamus [nTPM]":"11.8","Tissue RNA - thymus [nTPM]":"5.2","Tissue RNA - thyroid gland [nTPM]":"21.9","Tissue RNA - tongue [nTPM]":"24.8","Tissue RNA - tonsil [nTPM]":"10.8","Tissue RNA - urinary bladder [nTPM]":"15.2","Tissue RNA - vagina [nTPM]":"13.4","Tissue RNA - white matter [nTPM]":"16.0","Cell RNA - A-431 [nTPM]":"44.2","Cell RNA - A549 [nTPM]":"22.3","Cell RNA - AF22 [nTPM]":"25.1","Cell RNA - AN3-CA [nTPM]":"45.8","Cell RNA - ASC diff [nTPM]":"36.7","Cell RNA - ASC TERT1 [nTPM]":"33.9","Cell RNA - BEWO [nTPM]":"35.6","Cell RNA - BJ [nTPM]":"43.8","Cell RNA - BJ hTERT+ [nTPM]":"34.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"30.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"34.2","Cell RNA - CACO-2 [nTPM]":"22.6","Cell RNA - CAPAN-2 [nTPM]":"21.0","Cell RNA - Daudi [nTPM]":"10.8","Cell RNA - EFO-21 [nTPM]":"43.7","Cell RNA - fHDF\/TERT166 [nTPM]":"33.3","Cell RNA - GAMG [nTPM]":"18.5","Cell RNA - HaCaT [nTPM]":"17.1","Cell RNA - HAP1 [nTPM]":"23.9","Cell RNA - HBEC3-KT [nTPM]":"16.1","Cell RNA - HBF TERT88 [nTPM]":"39.4","Cell RNA - HDLM-2 [nTPM]":"38.0","Cell RNA - HEK 293 [nTPM]":"23.2","Cell RNA - HEL [nTPM]":"30.4","Cell RNA - HeLa [nTPM]":"24.7","Cell RNA - Hep G2 [nTPM]":"23.5","Cell RNA - HHSteC [nTPM]":"28.9","Cell RNA - HL-60 [nTPM]":"28.7","Cell RNA - HMC-1 [nTPM]":"28.2","Cell RNA - HSkMC [nTPM]":"25.2","Cell RNA - hTCEpi [nTPM]":"21.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"33.2","Cell RNA - hTERT-HME1 [nTPM]":"25.7","Cell RNA - hTERT-RPE1 [nTPM]":"28.3","Cell RNA - HUVEC TERT2 [nTPM]":"27.1","Cell RNA - JURKAT [nTPM]":"12.1","Cell RNA - K-562 [nTPM]":"38.6","Cell RNA - Karpas-707 [nTPM]":"47.7","Cell RNA - LHCN-M2 [nTPM]":"22.1","Cell RNA - MCF7 [nTPM]":"18.9","Cell RNA - MOLT-4 [nTPM]":"2.3","Cell RNA - NB-4 [nTPM]":"10.1","Cell RNA - NTERA-2 [nTPM]":"21.5","Cell RNA - OE19 [nTPM]":"16.6","Cell RNA - PC-3 [nTPM]":"19.8","Cell RNA - REH [nTPM]":"24.5","Cell RNA - RH-30 [nTPM]":"13.1","Cell RNA - RPMI-8226 [nTPM]":"31.2","Cell RNA - RPTEC TERT1 [nTPM]":"24.3","Cell RNA - RT4 [nTPM]":"30.5","Cell RNA - SCLC-21H [nTPM]":"15.9","Cell RNA - SH-SY5Y [nTPM]":"22.7","Cell RNA - SiHa [nTPM]":"46.9","Cell RNA - SK-BR-3 [nTPM]":"49.6","Cell RNA - SK-MEL-30 [nTPM]":"38.9","Cell RNA - SuSa [nTPM]":"18.9","Cell RNA - T-47d [nTPM]":"15.9","Cell RNA - THP-1 [nTPM]":"19.7","Cell RNA - TIME [nTPM]":"26.7","Cell RNA - U-138 MG [nTPM]":"38.3","Cell RNA - U-2 OS [nTPM]":"27.7","Cell RNA - U-2197 [nTPM]":"35.1","Cell RNA - U-251 MG [nTPM]":"38.4","Cell RNA - U-266\/70 [nTPM]":"32.1","Cell RNA - U-266\/84 [nTPM]":"33.3","Cell RNA - U-698 [nTPM]":"17.1","Cell RNA - U-87 MG [nTPM]":"44.7","Cell RNA - U-937 [nTPM]":"21.8","Cell RNA - WM-115 [nTPM]":"82.5","Blood RNA - basophil [nTPM]":"4.1","Blood RNA - classical monocyte [nTPM]":"5.6","Blood RNA - eosinophil [nTPM]":"6.1","Blood RNA - gdT-cell [nTPM]":"5.6","Blood RNA - intermediate monocyte [nTPM]":"8.4","Blood RNA - MAIT T-cell [nTPM]":"6.1","Blood RNA - memory B-cell [nTPM]":"6.1","Blood RNA - memory CD4 T-cell [nTPM]":"4.5","Blood RNA - memory CD8 T-cell [nTPM]":"4.4","Blood RNA - myeloid DC [nTPM]":"5.6","Blood RNA - naive B-cell [nTPM]":"3.2","Blood RNA - naive CD4 T-cell [nTPM]":"4.9","Blood RNA - naive CD8 T-cell [nTPM]":"4.5","Blood RNA - neutrophil [nTPM]":"1.4","Blood RNA - NK-cell [nTPM]":"4.7","Blood RNA - non-classical monocyte [nTPM]":"12.4","Blood RNA - plasmacytoid DC [nTPM]":"6.4","Blood RNA - T-reg [nTPM]":"6.8","Blood RNA - total PBMC [nTPM]":"4.4","Brain RNA - amygdala [nTPM]":"10.1","Brain RNA - basal ganglia [nTPM]":"14.3","Brain RNA - cerebellum [nTPM]":"10.6","Brain RNA - cerebral cortex [nTPM]":"11.7","Brain RNA - hippocampal formation [nTPM]":"10.7","Brain RNA - hypothalamus [nTPM]":"11.5","Brain RNA - medulla oblongata [nTPM]":"12.8","Brain RNA - midbrain [nTPM]":"10.9","Brain RNA - pons [nTPM]":"12.1","Brain RNA - spinal cord [nTPM]":"11.0","Brain RNA - thalamus [nTPM]":"11.8","Brain RNA - white matter [nTPM]":"16.0","Single Cell Type RNA - Adipocytes [nTPM]":"13.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.9","Single Cell Type RNA - Astrocytes [nTPM]":"26.8","Single Cell Type RNA - B-cells [nTPM]":"11.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"12.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"18.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"28.7","Single Cell Type RNA - dendritic cells [nTPM]":"9.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"18.6","Single Cell Type RNA - Early spermatids [nTPM]":"6.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.3","Single Cell Type RNA - Endothelial cells [nTPM]":"10.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"5.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.8","Single Cell Type RNA - Fibroblasts [nTPM]":"19.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.5","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"16.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.7","Single Cell Type RNA - Hepatocytes [nTPM]":"22.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.1","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"30.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.0","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"6.7","Single Cell Type RNA - Langerhans cells [nTPM]":"5.1","Single Cell Type RNA - Late spermatids [nTPM]":"2.8","Single Cell Type RNA - Leydig cells [nTPM]":"19.9","Single Cell Type RNA - Macrophages [nTPM]":"9.3","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"12.0","Single Cell Type RNA - Muller glia cells [nTPM]":"11.4","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"35.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"39.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.7","Single Cell Type RNA - Paneth cells [nTPM]":"3.8","Single Cell Type RNA - Peritubular cells [nTPM]":"18.8","Single Cell Type RNA - Plasma cells [nTPM]":"17.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.9","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.7","Single Cell Type RNA - Spermatocytes [nTPM]":"5.5","Single Cell Type RNA - Spermatogonia [nTPM]":"5.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"18.5","Single Cell Type RNA - T-cells [nTPM]":"8.4","Single Cell Type RNA - Theca cells [nTPM]":"12.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.8","Single Cell Type RNA - Urothelial cells [nTPM]":"9.9"},{"Gene":"CLCN1","Gene synonym":["ClC-1","CLC1"],"Ensembl":"ENSG00000188037","Gene description":"Chloride voltage-gated channel 1","Uniprot":["P35523"],"Chromosome":"7","Position":"143316111-143352083","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Voltage-gated channel"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"skeletal muscle":"65.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"149.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"1.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HSkMC":"1.6"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.71e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.9","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"65.9","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"1.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"15.9","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"1.6","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.6","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.8","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"32.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"149.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.7","Single Cell Type RNA - Paneth cells [nTPM]":"15.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"2.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"2.1"},{"Gene":"CLCN4","Gene synonym":["ClC-4","CLC4"],"Ensembl":"ENSG00000073464","Gene description":"Chloride voltage-gated channel 4","Uniprot":["P51793"],"Chromosome":"X","Position":"10156975-10237660","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"33.3","retina":"37.9","skeletal muscle":"45.0","tongue":"34.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"85.0","Cone photoreceptor cells":"102.2","Excitatory neurons":"45.7","Horizontal cells":"52.2","Inhibitory neurons":"54.0","Oligodendrocytes":"76.5","Rod photoreceptor cells":"42.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"2.6","neutrophil":"2.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"B-cells":"2.6","granulocytes":"2.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"GAMG":"25.3","HEL":"24.3","SCLC-21H":"24.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031313","HPA063637"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA031313":"AB_10601358","HPA063637":"AB_2685069"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.13e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.55e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Tissue RNA - adipose tissue [nTPM]":"2.6","Tissue RNA - adrenal gland [nTPM]":"2.7","Tissue RNA - amygdala [nTPM]":"16.2","Tissue RNA - appendix [nTPM]":"1.5","Tissue RNA - basal ganglia [nTPM]":"27.4","Tissue RNA - bone marrow [nTPM]":"1.8","Tissue RNA - breast [nTPM]":"1.1","Tissue RNA - cerebellum [nTPM]":"28.8","Tissue RNA - cerebral cortex [nTPM]":"23.1","Tissue RNA - cervix [nTPM]":"1.3","Tissue RNA - choroid plexus [nTPM]":"5.2","Tissue RNA - colon [nTPM]":"0.9","Tissue RNA - duodenum [nTPM]":"0.8","Tissue RNA - endometrium 1 [nTPM]":"0.6","Tissue RNA - epididymis [nTPM]":"22.6","Tissue RNA - esophagus [nTPM]":"1.7","Tissue RNA - fallopian tube [nTPM]":"2.9","Tissue RNA - gallbladder [nTPM]":"2.1","Tissue RNA - heart muscle [nTPM]":"12.3","Tissue RNA - hippocampal formation [nTPM]":"19.6","Tissue RNA - hypothalamus [nTPM]":"19.7","Tissue RNA - kidney [nTPM]":"2.8","Tissue RNA - liver [nTPM]":"3.2","Tissue RNA - lung [nTPM]":"3.0","Tissue RNA - lymph node [nTPM]":"2.8","Tissue RNA - medulla oblongata [nTPM]":"27.1","Tissue RNA - midbrain [nTPM]":"24.1","Tissue RNA - ovary [nTPM]":"1.6","Tissue RNA - pancreas [nTPM]":"2.2","Tissue RNA - parathyroid gland [nTPM]":"10.8","Tissue RNA - pituitary gland [nTPM]":"5.3","Tissue RNA - placenta [nTPM]":"1.1","Tissue RNA - pons [nTPM]":"24.5","Tissue RNA - prostate [nTPM]":"1.5","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"37.9","Tissue RNA - salivary gland [nTPM]":"2.2","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"45.0","Tissue RNA - skin 1 [nTPM]":"1.0","Tissue RNA - small intestine [nTPM]":"0.7","Tissue RNA - smooth muscle [nTPM]":"0.7","Tissue RNA - spinal cord [nTPM]":"18.5","Tissue RNA - spleen [nTPM]":"2.6","Tissue RNA - stomach 1 [nTPM]":"1.5","Tissue RNA - testis [nTPM]":"1.8","Tissue RNA - thalamus [nTPM]":"26.8","Tissue RNA - thymus [nTPM]":"2.6","Tissue RNA - thyroid gland [nTPM]":"6.5","Tissue RNA - tongue [nTPM]":"34.2","Tissue RNA - tonsil [nTPM]":"1.8","Tissue RNA - urinary bladder [nTPM]":"1.2","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"33.3","Cell RNA - A-431 [nTPM]":"5.9","Cell RNA - A549 [nTPM]":"4.6","Cell RNA - AF22 [nTPM]":"2.7","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"1.5","Cell RNA - ASC TERT1 [nTPM]":"2.5","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"9.1","Cell RNA - CAPAN-2 [nTPM]":"4.6","Cell RNA - Daudi [nTPM]":"5.0","Cell RNA - EFO-21 [nTPM]":"13.0","Cell RNA - fHDF\/TERT166 [nTPM]":"1.5","Cell RNA - GAMG [nTPM]":"25.3","Cell RNA - HaCaT [nTPM]":"1.4","Cell RNA - HAP1 [nTPM]":"1.4","Cell RNA - HBEC3-KT [nTPM]":"2.9","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"5.7","Cell RNA - HEL [nTPM]":"24.3","Cell RNA - HeLa [nTPM]":"2.2","Cell RNA - Hep G2 [nTPM]":"3.5","Cell RNA - HHSteC [nTPM]":"7.3","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"12.9","Cell RNA - hTCEpi [nTPM]":"3.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.0","Cell RNA - hTERT-HME1 [nTPM]":"1.5","Cell RNA - hTERT-RPE1 [nTPM]":"4.7","Cell RNA - HUVEC TERT2 [nTPM]":"9.4","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"1.5","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"3.3","Cell RNA - MCF7 [nTPM]":"1.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"4.0","Cell RNA - OE19 [nTPM]":"7.1","Cell RNA - PC-3 [nTPM]":"15.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"4.5","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"2.1","Cell RNA - RT4 [nTPM]":"0.8","Cell RNA - SCLC-21H [nTPM]":"24.1","Cell RNA - SH-SY5Y [nTPM]":"8.7","Cell RNA - SiHa [nTPM]":"8.6","Cell RNA - SK-BR-3 [nTPM]":"1.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"2.7","Cell RNA - T-47d [nTPM]":"1.7","Cell RNA - THP-1 [nTPM]":"2.7","Cell RNA - TIME [nTPM]":"7.4","Cell RNA - U-138 MG [nTPM]":"3.1","Cell RNA - U-2 OS [nTPM]":"5.8","Cell RNA - U-2197 [nTPM]":"15.3","Cell RNA - U-251 MG [nTPM]":"0.6","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"12.1","Cell RNA - U-698 [nTPM]":"1.8","Cell RNA - U-87 MG [nTPM]":"10.5","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"4.5","Blood RNA - basophil [nTPM]":"1.6","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"2.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"2.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"16.2","Brain RNA - basal ganglia [nTPM]":"27.4","Brain RNA - cerebellum [nTPM]":"28.8","Brain RNA - cerebral cortex [nTPM]":"23.1","Brain RNA - hippocampal formation [nTPM]":"19.6","Brain RNA - hypothalamus [nTPM]":"19.7","Brain RNA - medulla oblongata [nTPM]":"27.1","Brain RNA - midbrain [nTPM]":"24.1","Brain RNA - pons [nTPM]":"24.5","Brain RNA - spinal cord [nTPM]":"18.5","Brain RNA - thalamus [nTPM]":"26.8","Brain RNA - white matter [nTPM]":"33.3","Single Cell Type RNA - Adipocytes [nTPM]":"1.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.1","Single Cell Type RNA - Astrocytes [nTPM]":"11.8","Single Cell Type RNA - B-cells [nTPM]":"4.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"85.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"31.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"2.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"102.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.3","Single Cell Type RNA - Endothelial cells [nTPM]":"3.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.0","Single Cell Type RNA - Erythroid cells [nTPM]":"9.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"45.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"4.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"5.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.1","Single Cell Type RNA - Horizontal cells [nTPM]":"52.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"54.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.6","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"4.8","Single Cell Type RNA - Langerhans cells [nTPM]":"2.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"3.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"15.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"24.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"76.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"42.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"2.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"CLCN7","Gene synonym":["CLC-7","CLC7","OPTA2","PPP1R63"],"Ensembl":"ENSG00000103249","Gene description":"Chloride voltage-gated channel 7","Uniprot":["P51798"],"Chromosome":"16","Position":"1444934-1475084","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Osteopetrosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"74.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"42.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043019","HPA043586"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 62: Horizontal cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043019":"AB_10964727","HPA043586":"AB_10965322"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.23e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.21e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Tissue RNA - adipose tissue [nTPM]":"18.1","Tissue RNA - adrenal gland [nTPM]":"37.3","Tissue RNA - amygdala [nTPM]":"14.4","Tissue RNA - appendix [nTPM]":"16.9","Tissue RNA - basal ganglia [nTPM]":"14.2","Tissue RNA - bone marrow [nTPM]":"34.3","Tissue RNA - breast [nTPM]":"17.3","Tissue RNA - cerebellum [nTPM]":"12.8","Tissue RNA - cerebral cortex [nTPM]":"18.0","Tissue RNA - cervix [nTPM]":"18.7","Tissue RNA - choroid plexus [nTPM]":"18.0","Tissue RNA - colon [nTPM]":"20.0","Tissue RNA - duodenum [nTPM]":"16.6","Tissue RNA - endometrium 1 [nTPM]":"20.3","Tissue RNA - epididymis [nTPM]":"6.3","Tissue RNA - esophagus [nTPM]":"12.4","Tissue RNA - fallopian tube [nTPM]":"17.0","Tissue RNA - gallbladder [nTPM]":"12.3","Tissue RNA - heart muscle [nTPM]":"16.6","Tissue RNA - hippocampal formation [nTPM]":"14.2","Tissue RNA - hypothalamus [nTPM]":"14.1","Tissue RNA - kidney [nTPM]":"21.1","Tissue RNA - liver [nTPM]":"22.0","Tissue RNA - lung [nTPM]":"19.1","Tissue RNA - lymph node [nTPM]":"18.3","Tissue RNA - medulla oblongata [nTPM]":"17.9","Tissue RNA - midbrain [nTPM]":"19.2","Tissue RNA - ovary [nTPM]":"15.1","Tissue RNA - pancreas [nTPM]":"21.8","Tissue RNA - parathyroid gland [nTPM]":"20.8","Tissue RNA - pituitary gland [nTPM]":"21.7","Tissue RNA - placenta [nTPM]":"12.4","Tissue RNA - pons [nTPM]":"20.7","Tissue RNA - prostate [nTPM]":"16.5","Tissue RNA - rectum [nTPM]":"7.1","Tissue RNA - retina [nTPM]":"9.2","Tissue RNA - salivary gland [nTPM]":"16.8","Tissue RNA - seminal vesicle [nTPM]":"12.0","Tissue RNA - skeletal muscle [nTPM]":"28.0","Tissue RNA - skin 1 [nTPM]":"23.1","Tissue RNA - small intestine [nTPM]":"22.7","Tissue RNA - smooth muscle [nTPM]":"13.2","Tissue RNA - spinal cord [nTPM]":"11.9","Tissue RNA - spleen [nTPM]":"27.3","Tissue RNA - stomach 1 [nTPM]":"22.3","Tissue RNA - testis [nTPM]":"19.2","Tissue RNA - thalamus [nTPM]":"18.0","Tissue RNA - thymus [nTPM]":"15.6","Tissue RNA - thyroid gland [nTPM]":"23.1","Tissue RNA - tongue [nTPM]":"8.3","Tissue RNA - tonsil [nTPM]":"12.1","Tissue RNA - urinary bladder [nTPM]":"16.0","Tissue RNA - vagina [nTPM]":"11.9","Tissue RNA - white matter [nTPM]":"15.8","Cell RNA - A-431 [nTPM]":"14.2","Cell RNA - A549 [nTPM]":"36.9","Cell RNA - AF22 [nTPM]":"21.0","Cell RNA - AN3-CA [nTPM]":"33.7","Cell RNA - ASC diff [nTPM]":"41.3","Cell RNA - ASC TERT1 [nTPM]":"21.5","Cell RNA - BEWO [nTPM]":"34.3","Cell RNA - BJ [nTPM]":"18.9","Cell RNA - BJ hTERT+ [nTPM]":"36.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"35.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"41.5","Cell RNA - CACO-2 [nTPM]":"30.8","Cell RNA - CAPAN-2 [nTPM]":"51.2","Cell RNA - Daudi [nTPM]":"16.3","Cell RNA - EFO-21 [nTPM]":"38.6","Cell RNA - fHDF\/TERT166 [nTPM]":"23.7","Cell RNA - GAMG [nTPM]":"73.8","Cell RNA - HaCaT [nTPM]":"29.4","Cell RNA - HAP1 [nTPM]":"18.4","Cell RNA - HBEC3-KT [nTPM]":"21.0","Cell RNA - HBF TERT88 [nTPM]":"11.4","Cell RNA - HDLM-2 [nTPM]":"26.1","Cell RNA - HEK 293 [nTPM]":"31.5","Cell RNA - HEL [nTPM]":"11.6","Cell RNA - HeLa [nTPM]":"37.9","Cell RNA - Hep G2 [nTPM]":"30.0","Cell RNA - HHSteC [nTPM]":"72.4","Cell RNA - HL-60 [nTPM]":"29.4","Cell RNA - HMC-1 [nTPM]":"45.1","Cell RNA - HSkMC [nTPM]":"42.9","Cell RNA - hTCEpi [nTPM]":"28.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.1","Cell RNA - hTERT-HME1 [nTPM]":"28.5","Cell RNA - hTERT-RPE1 [nTPM]":"23.9","Cell RNA - HUVEC TERT2 [nTPM]":"23.0","Cell RNA - JURKAT [nTPM]":"36.3","Cell RNA - K-562 [nTPM]":"48.0","Cell RNA - Karpas-707 [nTPM]":"29.2","Cell RNA - LHCN-M2 [nTPM]":"18.5","Cell RNA - MCF7 [nTPM]":"28.4","Cell RNA - MOLT-4 [nTPM]":"21.3","Cell RNA - NB-4 [nTPM]":"50.6","Cell RNA - NTERA-2 [nTPM]":"21.7","Cell RNA - OE19 [nTPM]":"9.0","Cell RNA - PC-3 [nTPM]":"21.8","Cell RNA - REH [nTPM]":"96.7","Cell RNA - RH-30 [nTPM]":"13.3","Cell RNA - RPMI-8226 [nTPM]":"45.2","Cell RNA - RPTEC TERT1 [nTPM]":"16.4","Cell RNA - RT4 [nTPM]":"18.2","Cell RNA - SCLC-21H [nTPM]":"22.5","Cell RNA - SH-SY5Y [nTPM]":"24.9","Cell RNA - SiHa [nTPM]":"30.8","Cell RNA - SK-BR-3 [nTPM]":"37.5","Cell RNA - SK-MEL-30 [nTPM]":"120.2","Cell RNA - SuSa [nTPM]":"11.8","Cell RNA - T-47d [nTPM]":"33.6","Cell RNA - THP-1 [nTPM]":"78.0","Cell RNA - TIME [nTPM]":"26.3","Cell RNA - U-138 MG [nTPM]":"34.9","Cell RNA - U-2 OS [nTPM]":"16.2","Cell RNA - U-2197 [nTPM]":"39.1","Cell RNA - U-251 MG [nTPM]":"18.4","Cell RNA - U-266\/70 [nTPM]":"47.3","Cell RNA - U-266\/84 [nTPM]":"32.1","Cell RNA - U-698 [nTPM]":"16.5","Cell RNA - U-87 MG [nTPM]":"28.2","Cell RNA - U-937 [nTPM]":"54.3","Cell RNA - WM-115 [nTPM]":"22.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.6","Blood RNA - eosinophil [nTPM]":"1.2","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"2.7","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"1.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"1.2","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"3.4","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"14.4","Brain RNA - basal ganglia [nTPM]":"14.2","Brain RNA - cerebellum [nTPM]":"12.8","Brain RNA - cerebral cortex [nTPM]":"18.0","Brain RNA - hippocampal formation [nTPM]":"14.2","Brain RNA - hypothalamus [nTPM]":"14.1","Brain RNA - medulla oblongata [nTPM]":"17.9","Brain RNA - midbrain [nTPM]":"19.2","Brain RNA - pons [nTPM]":"20.7","Brain RNA - spinal cord [nTPM]":"11.9","Brain RNA - thalamus [nTPM]":"18.0","Brain RNA - white matter [nTPM]":"15.8","Single Cell Type RNA - Adipocytes [nTPM]":"12.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.5","Single Cell Type RNA - Astrocytes [nTPM]":"25.1","Single Cell Type RNA - B-cells [nTPM]":"16.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"45.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"8.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.2","Single Cell Type RNA - dendritic cells [nTPM]":"12.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"20.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"16.2","Single Cell Type RNA - Early spermatids [nTPM]":"10.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.9","Single Cell Type RNA - Endothelial cells [nTPM]":"11.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.0","Single Cell Type RNA - Erythroid cells [nTPM]":"8.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.9","Single Cell Type RNA - Fibroblasts [nTPM]":"11.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.9","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"24.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.8","Single Cell Type RNA - Hepatocytes [nTPM]":"15.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"36.3","Single Cell Type RNA - Horizontal cells [nTPM]":"74.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.5","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"28.3","Single Cell Type RNA - Langerhans cells [nTPM]":"11.5","Single Cell Type RNA - Late spermatids [nTPM]":"8.6","Single Cell Type RNA - Leydig cells [nTPM]":"11.5","Single Cell Type RNA - Macrophages [nTPM]":"29.6","Single Cell Type RNA - Melanocytes [nTPM]":"39.2","Single Cell Type RNA - Microglial cells [nTPM]":"24.4","Single Cell Type RNA - monocytes [nTPM]":"22.4","Single Cell Type RNA - Muller glia cells [nTPM]":"27.3","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.9","Single Cell Type RNA - Paneth cells [nTPM]":"7.3","Single Cell Type RNA - Peritubular cells [nTPM]":"8.2","Single Cell Type RNA - Plasma cells [nTPM]":"9.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"28.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.9","Single Cell Type RNA - Spermatocytes [nTPM]":"13.5","Single Cell Type RNA - Spermatogonia [nTPM]":"10.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.5","Single Cell Type RNA - T-cells [nTPM]":"9.4","Single Cell Type RNA - Theca cells [nTPM]":"19.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.1","Single Cell Type RNA - Urothelial cells [nTPM]":"5.2"},{"Gene":"CLDN1","Gene synonym":["ILVASC","SEMP1"],"Ensembl":"ENSG00000163347","Gene description":"Claudin 1","Uniprot":["O95832"],"Chromosome":"3","Position":"190305707-190322446","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"309.8","skin 1":"288.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"440.1","Basal prostatic cells":"291.1","Prostatic glandular cells":"501.6","Squamous epithelial cells":"298.2","Suprabasal keratinocytes":"836.1","Urothelial cells":"562.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"EFO-21":"658.6","HaCaT":"236.5","hTCEpi":"288.6","RPTEC TERT1":"414.9","RT4":"267.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"12","RNA pig brain regional specific nTPM":{"spinal cord":"25.4"},"Antibody":["CAB002602","HPA048319"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002602":null,"HPA048319":"AB_2680355"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.00e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.23e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Tissue RNA - adipose tissue [nTPM]":"40.8","Tissue RNA - adrenal gland [nTPM]":"47.9","Tissue RNA - amygdala [nTPM]":"1.5","Tissue RNA - appendix [nTPM]":"1.2","Tissue RNA - basal ganglia [nTPM]":"1.1","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"22.7","Tissue RNA - cerebellum [nTPM]":"0.8","Tissue RNA - cerebral cortex [nTPM]":"1.3","Tissue RNA - cervix [nTPM]":"17.7","Tissue RNA - choroid plexus [nTPM]":"20.7","Tissue RNA - colon [nTPM]":"1.7","Tissue RNA - duodenum [nTPM]":"1.1","Tissue RNA - endometrium 1 [nTPM]":"64.2","Tissue RNA - epididymis [nTPM]":"31.9","Tissue RNA - esophagus [nTPM]":"40.9","Tissue RNA - fallopian tube [nTPM]":"56.6","Tissue RNA - gallbladder [nTPM]":"15.5","Tissue RNA - heart muscle [nTPM]":"2.5","Tissue RNA - hippocampal formation [nTPM]":"1.5","Tissue RNA - hypothalamus [nTPM]":"1.2","Tissue RNA - kidney [nTPM]":"10.5","Tissue RNA - liver [nTPM]":"309.8","Tissue RNA - lung [nTPM]":"9.1","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"1.2","Tissue RNA - midbrain [nTPM]":"2.8","Tissue RNA - ovary [nTPM]":"6.3","Tissue RNA - pancreas [nTPM]":"34.3","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"2.4","Tissue RNA - placenta [nTPM]":"5.3","Tissue RNA - pons [nTPM]":"1.7","Tissue RNA - prostate [nTPM]":"13.6","Tissue RNA - rectum [nTPM]":"1.6","Tissue RNA - retina [nTPM]":"0.9","Tissue RNA - salivary gland [nTPM]":"34.0","Tissue RNA - seminal vesicle [nTPM]":"46.0","Tissue RNA - skeletal muscle [nTPM]":"1.1","Tissue RNA - skin 1 [nTPM]":"288.2","Tissue RNA - small intestine [nTPM]":"0.7","Tissue RNA - smooth muscle [nTPM]":"126.6","Tissue RNA - spinal cord [nTPM]":"0.7","Tissue RNA - spleen [nTPM]":"1.5","Tissue RNA - stomach 1 [nTPM]":"1.0","Tissue RNA - testis [nTPM]":"4.3","Tissue RNA - thalamus [nTPM]":"1.1","Tissue RNA - thymus [nTPM]":"9.4","Tissue RNA - thyroid gland [nTPM]":"36.2","Tissue RNA - tongue [nTPM]":"4.9","Tissue RNA - tonsil [nTPM]":"44.2","Tissue RNA - urinary bladder [nTPM]":"40.4","Tissue RNA - vagina [nTPM]":"35.9","Tissue RNA - white matter [nTPM]":"1.0","Cell RNA - A-431 [nTPM]":"34.0","Cell RNA - A549 [nTPM]":"29.7","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"2.5","Cell RNA - BJ hTERT+ [nTPM]":"52.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.1","Cell RNA - CACO-2 [nTPM]":"17.7","Cell RNA - CAPAN-2 [nTPM]":"69.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"658.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.3","Cell RNA - GAMG [nTPM]":"58.5","Cell RNA - HaCaT [nTPM]":"236.5","Cell RNA - HAP1 [nTPM]":"1.5","Cell RNA - HBEC3-KT [nTPM]":"77.7","Cell RNA - HBF TERT88 [nTPM]":"6.2","Cell RNA - HDLM-2 [nTPM]":"0.9","Cell RNA - HEK 293 [nTPM]":"1.4","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"9.3","Cell RNA - Hep G2 [nTPM]":"41.5","Cell RNA - HHSteC [nTPM]":"49.6","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.5","Cell RNA - hTCEpi [nTPM]":"288.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.0","Cell RNA - hTERT-HME1 [nTPM]":"87.0","Cell RNA - hTERT-RPE1 [nTPM]":"2.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.6","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"6.5","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"1.5","Cell RNA - OE19 [nTPM]":"2.3","Cell RNA - PC-3 [nTPM]":"5.5","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.6","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"414.9","Cell RNA - RT4 [nTPM]":"267.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"31.0","Cell RNA - SK-BR-3 [nTPM]":"5.7","Cell RNA - SK-MEL-30 [nTPM]":"18.4","Cell RNA - SuSa [nTPM]":"3.5","Cell RNA - T-47d [nTPM]":"53.5","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"12.9","Cell RNA - U-138 MG [nTPM]":"0.6","Cell RNA - U-2 OS [nTPM]":"9.9","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"1.4","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"1.2","Cell RNA - U-87 MG [nTPM]":"0.5","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.5","Brain RNA - basal ganglia [nTPM]":"1.1","Brain RNA - cerebellum [nTPM]":"0.8","Brain RNA - cerebral cortex [nTPM]":"1.3","Brain RNA - hippocampal formation [nTPM]":"1.5","Brain RNA - hypothalamus [nTPM]":"1.2","Brain RNA - medulla oblongata [nTPM]":"1.2","Brain RNA - midbrain [nTPM]":"2.8","Brain RNA - pons [nTPM]":"1.7","Brain RNA - spinal cord [nTPM]":"0.7","Brain RNA - thalamus [nTPM]":"1.1","Brain RNA - white matter [nTPM]":"1.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"34.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"440.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"291.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"217.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"84.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"35.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"170.1","Single Cell Type RNA - Club cells [nTPM]":"143.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"203.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"44.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.0","Single Cell Type RNA - Endothelial cells [nTPM]":"7.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"56.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"29.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"100.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"188.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"54.9","Single Cell Type RNA - Kupffer cells [nTPM]":"3.8","Single Cell Type RNA - Langerhans cells [nTPM]":"66.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.7","Single Cell Type RNA - Leydig cells [nTPM]":"15.5","Single Cell Type RNA - Macrophages [nTPM]":"8.5","Single Cell Type RNA - Melanocytes [nTPM]":"32.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"5.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"24.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"139.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"35.3","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"501.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"144.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"298.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"836.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"33.8","Single Cell Type RNA - T-cells [nTPM]":"2.6","Single Cell Type RNA - Theca cells [nTPM]":"5.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.0","Single Cell Type RNA - Urothelial cells [nTPM]":"562.9"},{"Gene":"CLDN16","Gene synonym":["HOMG3","PCLN1"],"Ensembl":"ENSG00000113946","Gene description":"Claudin 16","Uniprot":["Q9Y5I7"],"Chromosome":"3","Position":"190322541-190412138","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Primary hypomagnesemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"kidney":"63.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Distal tubular cells":"187.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"15","RNA cancer specific FPKM":{"ovarian cancer":"39.8","thyroid cancer":"29.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"153","RNA cell line specific nTPM":{"EFO-21":"691.6","RPTEC TERT1":"233.2"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056020"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA056020":"AB_2683011"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.99e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.7","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"1.5","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"0.5","Tissue RNA - fallopian tube [nTPM]":"2.9","Tissue RNA - gallbladder [nTPM]":"0.7","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"63.6","Tissue RNA - liver [nTPM]":"2.2","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"1.5","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"0.9","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"3.2","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"9.7","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"1.0","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"691.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.7","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.9","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"233.2","Cell RNA - RT4 [nTPM]":"0.6","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"2.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"1.4","Cell RNA - U-266\/84 [nTPM]":"1.2","Cell RNA - U-698 [nTPM]":"3.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"1.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"187.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.4","Single Cell Type RNA - Early spermatids [nTPM]":"2.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"0.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"1.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.2","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"3.1"},{"Gene":"CLDN19","Gene synonym":[],"Ensembl":"ENSG00000164007","Gene description":"Claudin 19","Uniprot":["Q8N6F1"],"Chromosome":"1","Position":"42733093-42740254","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Disease variant","Primary hypomagnesemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"choroid plexus":"19.8","kidney":"39.1","placenta":"9.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Extravillous trophoblasts":"221.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"2.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"CACO-2":"3.0","Hep G2":"6.3","SuSa":"3.5"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"olfactory bulb":"5.4"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"spinal cord":"41.8"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.8","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"1.1","Tissue RNA - cerebellum [nTPM]":"0.4","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"19.8","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"1.3","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"39.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"9.8","Tissue RNA - pons [nTPM]":"0.6","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.8","Tissue RNA - seminal vesicle [nTPM]":"0.7","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"1.6","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.7","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"3.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"6.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"3.5","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.4","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"1.3","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.6","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"221.6","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.4","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CLDN3","Gene synonym":["C7orf1","CPE-R2","CPETR2","HRVP1","RVP1"],"Ensembl":"ENSG00000165215","Gene description":"Claudin 3","Uniprot":["O15551"],"Chromosome":"7","Position":"73768997-73770270","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Williams-Beuren syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"263.1","thyroid gland":"116.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"1839.9","Endometrial ciliated cells":"1221.7","Glandular and luminal cells":"1555.7","Intestinal goblet cells":"1471.3","Paneth cells":"2326.0","Proximal enterocytes":"3162.1","Undifferentiated cells":"1266.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"529.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"230.7","PC-3":"47.6","RPMI-8226":"40.5","SCLC-21H":"58.0","T-47d":"105.4"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"1.5"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"midbrain":"9.7"},"Antibody":["HPA014361"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA014361":"AB_2668982"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.39e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.72e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.7","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"7.8","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"26.7","Tissue RNA - cerebellum [nTPM]":"4.2","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"12.3","Tissue RNA - choroid plexus [nTPM]":"37.6","Tissue RNA - colon [nTPM]":"263.1","Tissue RNA - duodenum [nTPM]":"54.4","Tissue RNA - endometrium 1 [nTPM]":"7.5","Tissue RNA - epididymis [nTPM]":"1.4","Tissue RNA - esophagus [nTPM]":"1.3","Tissue RNA - fallopian tube [nTPM]":"29.6","Tissue RNA - gallbladder [nTPM]":"2.2","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"1.1","Tissue RNA - hypothalamus [nTPM]":"1.2","Tissue RNA - kidney [nTPM]":"46.5","Tissue RNA - liver [nTPM]":"40.4","Tissue RNA - lung [nTPM]":"10.7","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"1.3","Tissue RNA - midbrain [nTPM]":"1.9","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"96.6","Tissue RNA - parathyroid gland [nTPM]":"1.5","Tissue RNA - pituitary gland [nTPM]":"27.7","Tissue RNA - placenta [nTPM]":"1.0","Tissue RNA - pons [nTPM]":"0.6","Tissue RNA - prostate [nTPM]":"58.3","Tissue RNA - rectum [nTPM]":"17.5","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"72.9","Tissue RNA - seminal vesicle [nTPM]":"8.3","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"9.6","Tissue RNA - small intestine [nTPM]":"169.5","Tissue RNA - smooth muscle [nTPM]":"0.8","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"1.4","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"0.9","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"116.3","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"1.2","Tissue RNA - urinary bladder [nTPM]":"1.5","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"2.5","Cell RNA - A549 [nTPM]":"3.6","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"17.8","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"4.2","Cell RNA - CAPAN-2 [nTPM]":"35.7","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"9.9","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"1.0","Cell RNA - HAP1 [nTPM]":"0.4","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"4.9","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.8","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"230.7","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"1.2","Cell RNA - NTERA-2 [nTPM]":"2.1","Cell RNA - OE19 [nTPM]":"9.1","Cell RNA - PC-3 [nTPM]":"47.6","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"40.5","Cell RNA - RPTEC TERT1 [nTPM]":"2.1","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"58.0","Cell RNA - SH-SY5Y [nTPM]":"0.7","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"33.6","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"105.4","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.6","Cell RNA - U-2197 [nTPM]":"0.9","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"4.2","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"1.1","Brain RNA - hypothalamus [nTPM]":"1.2","Brain RNA - medulla oblongata [nTPM]":"1.3","Brain RNA - midbrain [nTPM]":"1.9","Brain RNA - pons [nTPM]":"0.6","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"0.9","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"1.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"37.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"13.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"60.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"43.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"289.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"182.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"287.4","Single Cell Type RNA - Club cells [nTPM]":"86.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"126.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"63.9","Single Cell Type RNA - dendritic cells [nTPM]":"5.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"1839.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"297.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1221.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"130.5","Single Cell Type RNA - Endothelial cells [nTPM]":"10.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"606.1","Single Cell Type RNA - Erythroid cells [nTPM]":"5.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.7","Single Cell Type RNA - Fibroblasts [nTPM]":"4.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1555.7","Single Cell Type RNA - granulocytes [nTPM]":"28.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"40.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1471.3","Single Cell Type RNA - Ionocytes [nTPM]":"116.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"9.9","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"2.0","Single Cell Type RNA - Muller glia cells [nTPM]":"11.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"36.7","Single Cell Type RNA - Paneth cells [nTPM]":"2326.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"4.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"433.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3162.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"58.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"498.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"72.4","Single Cell Type RNA - T-cells [nTPM]":"17.5","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1266.0","Single Cell Type RNA - Urothelial cells [nTPM]":"607.3"},{"Gene":"CLDN4","Gene synonym":["CPE-R","CPETR","CPETR1","hCPE-R","WBSCR8"],"Ensembl":"ENSG00000189143","Gene description":"Claudin 4","Uniprot":["O14493"],"Chromosome":"7","Position":"73799542-73832690","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":["Cancer-related genes","Williams-Beuren syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"305.0","urinary bladder":"303.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"3149.1","Glandular and luminal cells":"2298.8","Paneth cells":"2081.0","Prostatic glandular cells":"2184.8","Urothelial cells":"8033.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"midbrain":"1.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"358.1","BEWO":"395.0","CAPAN-2":"761.4","MCF7":"400.2","OE19":"402.0","PC-3":"495.0","RT4":"340.2","SK-BR-3":"636.8"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002610"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB002610":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.28e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.46e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.6","Tissue RNA - adrenal gland [nTPM]":"0.4","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"23.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"69.0","Tissue RNA - cerebellum [nTPM]":"0.8","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"61.2","Tissue RNA - choroid plexus [nTPM]":"4.8","Tissue RNA - colon [nTPM]":"256.3","Tissue RNA - duodenum [nTPM]":"126.9","Tissue RNA - endometrium 1 [nTPM]":"26.7","Tissue RNA - epididymis [nTPM]":"24.4","Tissue RNA - esophagus [nTPM]":"305.0","Tissue RNA - fallopian tube [nTPM]":"75.8","Tissue RNA - gallbladder [nTPM]":"48.9","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"116.2","Tissue RNA - liver [nTPM]":"4.8","Tissue RNA - lung [nTPM]":"64.0","Tissue RNA - lymph node [nTPM]":"1.0","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"1.5","Tissue RNA - ovary [nTPM]":"1.2","Tissue RNA - pancreas [nTPM]":"116.2","Tissue RNA - parathyroid gland [nTPM]":"51.9","Tissue RNA - pituitary gland [nTPM]":"13.1","Tissue RNA - placenta [nTPM]":"36.3","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"82.2","Tissue RNA - rectum [nTPM]":"123.3","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"204.6","Tissue RNA - seminal vesicle [nTPM]":"39.1","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"180.8","Tissue RNA - small intestine [nTPM]":"190.6","Tissue RNA - smooth muscle [nTPM]":"7.3","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.7","Tissue RNA - stomach 1 [nTPM]":"13.3","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"10.7","Tissue RNA - thyroid gland [nTPM]":"111.7","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"37.5","Tissue RNA - urinary bladder [nTPM]":"303.5","Tissue RNA - vagina [nTPM]":"105.7","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"358.1","Cell RNA - A549 [nTPM]":"4.4","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"1.5","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"395.0","Cell RNA - BJ [nTPM]":"3.3","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"184.9","Cell RNA - CAPAN-2 [nTPM]":"761.4","Cell RNA - Daudi [nTPM]":"0.6","Cell RNA - EFO-21 [nTPM]":"28.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"2.6","Cell RNA - HaCaT [nTPM]":"193.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.5","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"0.7","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"20.3","Cell RNA - Hep G2 [nTPM]":"127.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.9","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"1.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.4","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"400.2","Cell RNA - MOLT-4 [nTPM]":"0.7","Cell RNA - NB-4 [nTPM]":"1.9","Cell RNA - NTERA-2 [nTPM]":"0.7","Cell RNA - OE19 [nTPM]":"402.0","Cell RNA - PC-3 [nTPM]":"495.0","Cell RNA - REH [nTPM]":"0.5","Cell RNA - RH-30 [nTPM]":"6.9","Cell RNA - RPMI-8226 [nTPM]":"7.6","Cell RNA - RPTEC TERT1 [nTPM]":"92.4","Cell RNA - RT4 [nTPM]":"340.2","Cell RNA - SCLC-21H [nTPM]":"79.5","Cell RNA - SH-SY5Y [nTPM]":"1.7","Cell RNA - SiHa [nTPM]":"0.4","Cell RNA - SK-BR-3 [nTPM]":"636.8","Cell RNA - SK-MEL-30 [nTPM]":"0.8","Cell RNA - SuSa [nTPM]":"21.6","Cell RNA - T-47d [nTPM]":"250.9","Cell RNA - THP-1 [nTPM]":"0.9","Cell RNA - TIME [nTPM]":"0.5","Cell RNA - U-138 MG [nTPM]":"0.9","Cell RNA - U-2 OS [nTPM]":"13.7","Cell RNA - U-2197 [nTPM]":"3.1","Cell RNA - U-251 MG [nTPM]":"3.5","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"0.7","Cell RNA - U-698 [nTPM]":"0.7","Cell RNA - U-87 MG [nTPM]":"0.6","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.8","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"1.5","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"5.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"275.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"230.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"12.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3149.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"641.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.3","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1255.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"548.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"287.4","Single Cell Type RNA - Club cells [nTPM]":"954.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"218.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"771.7","Single Cell Type RNA - dendritic cells [nTPM]":"18.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"1985.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"1026.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1201.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"231.0","Single Cell Type RNA - Endothelial cells [nTPM]":"41.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"675.5","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"447.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"739.7","Single Cell Type RNA - Fibroblasts [nTPM]":"27.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"94.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2298.8","Single Cell Type RNA - granulocytes [nTPM]":"27.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"76.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1266.9","Single Cell Type RNA - Ionocytes [nTPM]":"905.3","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"8.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"29.3","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"15.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"950.2","Single Cell Type RNA - Paneth cells [nTPM]":"2081.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2184.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1906.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"21.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"635.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"68.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1068.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"54.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"956.1","Single Cell Type RNA - T-cells [nTPM]":"40.7","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"965.1","Single Cell Type RNA - Urothelial cells [nTPM]":"8033.4"},{"Gene":"CLIC2","Gene synonym":["CLCNL2","XAP121"],"Ensembl":"ENSG00000155962","Gene description":"Chloride intracellular channel 2","Uniprot":["O15247"],"Chromosome":"X","Position":"155276211-155334657","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"51.2","Alveolar cells type 1":"89.8","Alveolar cells type 2":"54.9","Endothelial cells":"60.4","Erythroid cells":"70.7","Kupffer cells":"73.5","Langerhans cells":"135.0","monocytes":"71.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"18.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"intermediate monocyte":"18.6","myeloid DC":"47.9","non-classical monocyte":"14.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"16","RNA blood lineage specific nTPM":{"dendritic cells":"47.9","monocytes":"18.6"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"HDLM-2":"103.3","K-562":"60.4","Karpas-707":"53.4","RPMI-8226":"92.2"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047381","HPA060101"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"150000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA047381":"AB_2680022","HPA060101":"AB_2684204"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.74e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Tissue RNA - adipose tissue [nTPM]":"23.1","Tissue RNA - adrenal gland [nTPM]":"7.1","Tissue RNA - amygdala [nTPM]":"6.9","Tissue RNA - appendix [nTPM]":"16.7","Tissue RNA - basal ganglia [nTPM]":"7.8","Tissue RNA - bone marrow [nTPM]":"9.8","Tissue RNA - breast [nTPM]":"16.7","Tissue RNA - cerebellum [nTPM]":"6.9","Tissue RNA - cerebral cortex [nTPM]":"18.1","Tissue RNA - cervix [nTPM]":"20.1","Tissue RNA - choroid plexus [nTPM]":"7.6","Tissue RNA - colon [nTPM]":"10.9","Tissue RNA - duodenum [nTPM]":"8.7","Tissue RNA - endometrium 1 [nTPM]":"22.6","Tissue RNA - epididymis [nTPM]":"7.8","Tissue RNA - esophagus [nTPM]":"9.4","Tissue RNA - fallopian tube [nTPM]":"12.5","Tissue RNA - gallbladder [nTPM]":"19.0","Tissue RNA - heart muscle [nTPM]":"14.6","Tissue RNA - hippocampal formation [nTPM]":"7.1","Tissue RNA - hypothalamus [nTPM]":"7.0","Tissue RNA - kidney [nTPM]":"5.8","Tissue RNA - liver [nTPM]":"12.8","Tissue RNA - lung [nTPM]":"30.6","Tissue RNA - lymph node [nTPM]":"30.2","Tissue RNA - medulla oblongata [nTPM]":"7.7","Tissue RNA - midbrain [nTPM]":"6.9","Tissue RNA - ovary [nTPM]":"21.6","Tissue RNA - pancreas [nTPM]":"3.5","Tissue RNA - parathyroid gland [nTPM]":"4.6","Tissue RNA - pituitary gland [nTPM]":"4.5","Tissue RNA - placenta [nTPM]":"9.3","Tissue RNA - pons [nTPM]":"7.4","Tissue RNA - prostate [nTPM]":"4.6","Tissue RNA - rectum [nTPM]":"13.6","Tissue RNA - retina [nTPM]":"2.4","Tissue RNA - salivary gland [nTPM]":"6.2","Tissue RNA - seminal vesicle [nTPM]":"6.3","Tissue RNA - skeletal muscle [nTPM]":"4.4","Tissue RNA - skin 1 [nTPM]":"6.1","Tissue RNA - small intestine [nTPM]":"10.3","Tissue RNA - smooth muscle [nTPM]":"17.7","Tissue RNA - spinal cord [nTPM]":"7.7","Tissue RNA - spleen [nTPM]":"50.1","Tissue RNA - stomach 1 [nTPM]":"8.5","Tissue RNA - testis [nTPM]":"3.2","Tissue RNA - thalamus [nTPM]":"8.5","Tissue RNA - thymus [nTPM]":"14.5","Tissue RNA - thyroid gland [nTPM]":"31.8","Tissue RNA - tongue [nTPM]":"14.3","Tissue RNA - tonsil [nTPM]":"25.6","Tissue RNA - urinary bladder [nTPM]":"15.9","Tissue RNA - vagina [nTPM]":"10.7","Tissue RNA - white matter [nTPM]":"7.8","Cell RNA - A-431 [nTPM]":"0.7","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"1.0","Cell RNA - AN3-CA [nTPM]":"0.9","Cell RNA - ASC diff [nTPM]":"1.0","Cell RNA - ASC TERT1 [nTPM]":"4.7","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"2.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"103.3","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"16.4","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"1.4","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"60.4","Cell RNA - Karpas-707 [nTPM]":"53.4","Cell RNA - LHCN-M2 [nTPM]":"0.3","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"1.3","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"92.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"0.9","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"1.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"5.3","Cell RNA - U-2 OS [nTPM]":"1.6","Cell RNA - U-2197 [nTPM]":"2.0","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"3.3","Cell RNA - U-266\/84 [nTPM]":"4.6","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"2.7","Cell RNA - U-937 [nTPM]":"2.6","Cell RNA - WM-115 [nTPM]":"1.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"3.5","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"18.6","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"47.9","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"1.4","Blood RNA - NK-cell [nTPM]":"2.0","Blood RNA - non-classical monocyte [nTPM]":"14.2","Blood RNA - plasmacytoid DC [nTPM]":"5.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"2.1","Brain RNA - amygdala [nTPM]":"6.9","Brain RNA - basal ganglia [nTPM]":"7.8","Brain RNA - cerebellum [nTPM]":"6.9","Brain RNA - cerebral cortex [nTPM]":"18.1","Brain RNA - hippocampal formation [nTPM]":"7.1","Brain RNA - hypothalamus [nTPM]":"7.0","Brain RNA - medulla oblongata [nTPM]":"7.7","Brain RNA - midbrain [nTPM]":"6.9","Brain RNA - pons [nTPM]":"7.4","Brain RNA - spinal cord [nTPM]":"7.7","Brain RNA - thalamus [nTPM]":"8.5","Brain RNA - white matter [nTPM]":"7.8","Single Cell Type RNA - Adipocytes [nTPM]":"51.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"89.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"54.9","Single Cell Type RNA - Astrocytes [nTPM]":"3.9","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"1.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"5.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.3","Single Cell Type RNA - Endothelial cells [nTPM]":"60.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"70.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"25.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"27.1","Single Cell Type RNA - Hepatocytes [nTPM]":"1.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"73.5","Single Cell Type RNA - Langerhans cells [nTPM]":"135.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.1","Single Cell Type RNA - Leydig cells [nTPM]":"13.7","Single Cell Type RNA - Macrophages [nTPM]":"34.5","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"71.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"9.4","Single Cell Type RNA - Plasma cells [nTPM]":"2.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"2.6","Single Cell Type RNA - Theca cells [nTPM]":"5.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"1.9"},{"Gene":"CLIC5","Gene synonym":["DFNB102"],"Ensembl":"ENSG00000112782","Gene description":"Chloride intracellular channel 5","Uniprot":["Q9NZA1"],"Chromosome":"6","Position":"45880827-46080348","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Hearing","Ion transport","Sensory transduction","Transport","Vision"],"Molecular function":["Chloride channel","Ion channel","Voltage-gated channel"],"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"102.7","skeletal muscle":"289.7","tongue":"98.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"509.6","Cardiomyocytes":"285.7","Distal enterocytes":"164.2","Late spermatids":"93.8","Proximal enterocytes":"126.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"11.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"5.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"17","RNA blood lineage specific nTPM":{"T-cells":"5.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"13.5","EFO-21":"9.2","HDLM-2":"4.7","REH":"11.9","U-266\/70":"12.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074371"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"400000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear speckles"],"Antibody RRID":{"HPA074371":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Tissue RNA - adipose tissue [nTPM]":"18.9","Tissue RNA - adrenal gland [nTPM]":"1.5","Tissue RNA - amygdala [nTPM]":"3.2","Tissue RNA - appendix [nTPM]":"4.3","Tissue RNA - basal ganglia [nTPM]":"4.4","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"6.5","Tissue RNA - cerebellum [nTPM]":"1.5","Tissue RNA - cerebral cortex [nTPM]":"2.9","Tissue RNA - cervix [nTPM]":"19.0","Tissue RNA - choroid plexus [nTPM]":"0.5","Tissue RNA - colon [nTPM]":"28.6","Tissue RNA - duodenum [nTPM]":"20.9","Tissue RNA - endometrium 1 [nTPM]":"2.1","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"2.9","Tissue RNA - fallopian tube [nTPM]":"4.5","Tissue RNA - gallbladder [nTPM]":"3.0","Tissue RNA - heart muscle [nTPM]":"102.7","Tissue RNA - hippocampal formation [nTPM]":"2.1","Tissue RNA - hypothalamus [nTPM]":"5.0","Tissue RNA - kidney [nTPM]":"54.7","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"70.8","Tissue RNA - lymph node [nTPM]":"1.7","Tissue RNA - medulla oblongata [nTPM]":"2.1","Tissue RNA - midbrain [nTPM]":"3.8","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"1.1","Tissue RNA - parathyroid gland [nTPM]":"1.7","Tissue RNA - pituitary gland [nTPM]":"3.0","Tissue RNA - placenta [nTPM]":"16.5","Tissue RNA - pons [nTPM]":"2.2","Tissue RNA - prostate [nTPM]":"2.6","Tissue RNA - rectum [nTPM]":"25.8","Tissue RNA - retina [nTPM]":"16.9","Tissue RNA - salivary gland [nTPM]":"2.7","Tissue RNA - seminal vesicle [nTPM]":"1.4","Tissue RNA - skeletal muscle [nTPM]":"289.7","Tissue RNA - skin 1 [nTPM]":"1.2","Tissue RNA - small intestine [nTPM]":"36.6","Tissue RNA - smooth muscle [nTPM]":"2.3","Tissue RNA - spinal cord [nTPM]":"1.8","Tissue RNA - spleen [nTPM]":"44.5","Tissue RNA - stomach 1 [nTPM]":"1.6","Tissue RNA - testis [nTPM]":"1.4","Tissue RNA - thalamus [nTPM]":"5.5","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"7.3","Tissue RNA - tongue [nTPM]":"98.3","Tissue RNA - tonsil [nTPM]":"1.9","Tissue RNA - urinary bladder [nTPM]":"2.0","Tissue RNA - vagina [nTPM]":"2.6","Tissue RNA - white matter [nTPM]":"1.9","Cell RNA - A-431 [nTPM]":"0.9","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.6","Cell RNA - CAPAN-2 [nTPM]":"13.5","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"9.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"4.7","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"1.6","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"11.9","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"2.9","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"12.8","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.4","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"5.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"2.0","Blood RNA - memory CD8 T-cell [nTPM]":"1.3","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"1.0","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"3.2","Brain RNA - basal ganglia [nTPM]":"4.4","Brain RNA - cerebellum [nTPM]":"1.5","Brain RNA - cerebral cortex [nTPM]":"2.9","Brain RNA - hippocampal formation [nTPM]":"2.1","Brain RNA - hypothalamus [nTPM]":"5.0","Brain RNA - medulla oblongata [nTPM]":"2.1","Brain RNA - midbrain [nTPM]":"3.8","Brain RNA - pons [nTPM]":"2.2","Brain RNA - spinal cord [nTPM]":"1.8","Brain RNA - thalamus [nTPM]":"5.5","Brain RNA - white matter [nTPM]":"1.9","Single Cell Type RNA - Adipocytes [nTPM]":"59.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"509.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"30.0","Single Cell Type RNA - Astrocytes [nTPM]":"4.6","Single Cell Type RNA - B-cells [nTPM]":"1.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"285.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"26.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"164.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.7","Single Cell Type RNA - Early spermatids [nTPM]":"52.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"29.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"7.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.7","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"93.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"34.7","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"53.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.9","Single Cell Type RNA - Paneth cells [nTPM]":"51.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"3.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"126.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.2","Single Cell Type RNA - T-cells [nTPM]":"5.8","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.5","Single Cell Type RNA - Urothelial cells [nTPM]":"4.3"},{"Gene":"CLN3","Gene synonym":["BTN1","BTS","JNCL"],"Ensembl":"ENSG00000188603","Gene description":"CLN3 lysosomal\/endosomal transmembrane protein, battenin","Uniprot":["Q13286"],"Chromosome":"16","Position":"28474111-28495575","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration","Neuronal ceroid lipofuscinosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"315.9","Extravillous trophoblasts":"106.9","Syncytiotrophoblasts":"451.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"178.0","SK-BR-3":"186.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063280"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA063280":"AB_2684975"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Tissue RNA - adipose tissue [nTPM]":"18.1","Tissue RNA - adrenal gland [nTPM]":"30.5","Tissue RNA - amygdala [nTPM]":"13.1","Tissue RNA - appendix [nTPM]":"19.6","Tissue RNA - basal ganglia [nTPM]":"14.2","Tissue RNA - bone marrow [nTPM]":"13.4","Tissue RNA - breast [nTPM]":"21.4","Tissue RNA - cerebellum [nTPM]":"14.2","Tissue RNA - cerebral cortex [nTPM]":"16.0","Tissue RNA - cervix [nTPM]":"16.9","Tissue RNA - choroid plexus [nTPM]":"16.5","Tissue RNA - colon [nTPM]":"38.3","Tissue RNA - duodenum [nTPM]":"21.9","Tissue RNA - endometrium 1 [nTPM]":"15.9","Tissue RNA - epididymis [nTPM]":"9.9","Tissue RNA - esophagus [nTPM]":"22.2","Tissue RNA - fallopian tube [nTPM]":"16.0","Tissue RNA - gallbladder [nTPM]":"15.2","Tissue RNA - heart muscle [nTPM]":"11.7","Tissue RNA - hippocampal formation [nTPM]":"13.2","Tissue RNA - hypothalamus [nTPM]":"13.6","Tissue RNA - kidney [nTPM]":"21.2","Tissue RNA - liver [nTPM]":"31.9","Tissue RNA - lung [nTPM]":"23.6","Tissue RNA - lymph node [nTPM]":"13.8","Tissue RNA - medulla oblongata [nTPM]":"14.6","Tissue RNA - midbrain [nTPM]":"13.6","Tissue RNA - ovary [nTPM]":"16.8","Tissue RNA - pancreas [nTPM]":"27.7","Tissue RNA - parathyroid gland [nTPM]":"30.0","Tissue RNA - pituitary gland [nTPM]":"8.2","Tissue RNA - placenta [nTPM]":"36.9","Tissue RNA - pons [nTPM]":"15.1","Tissue RNA - prostate [nTPM]":"17.3","Tissue RNA - rectum [nTPM]":"29.2","Tissue RNA - retina [nTPM]":"3.1","Tissue RNA - salivary gland [nTPM]":"34.5","Tissue RNA - seminal vesicle [nTPM]":"21.0","Tissue RNA - skeletal muscle [nTPM]":"14.5","Tissue RNA - skin 1 [nTPM]":"24.1","Tissue RNA - small intestine [nTPM]":"25.7","Tissue RNA - smooth muscle [nTPM]":"13.3","Tissue RNA - spinal cord [nTPM]":"13.5","Tissue RNA - spleen [nTPM]":"20.4","Tissue RNA - stomach 1 [nTPM]":"26.1","Tissue RNA - testis [nTPM]":"7.9","Tissue RNA - thalamus [nTPM]":"15.6","Tissue RNA - thymus [nTPM]":"14.0","Tissue RNA - thyroid gland [nTPM]":"24.7","Tissue RNA - tongue [nTPM]":"13.8","Tissue RNA - tonsil [nTPM]":"12.1","Tissue RNA - urinary bladder [nTPM]":"19.3","Tissue RNA - vagina [nTPM]":"15.6","Tissue RNA - white matter [nTPM]":"17.1","Cell RNA - A-431 [nTPM]":"23.1","Cell RNA - A549 [nTPM]":"39.2","Cell RNA - AF22 [nTPM]":"15.4","Cell RNA - AN3-CA [nTPM]":"38.4","Cell RNA - ASC diff [nTPM]":"41.1","Cell RNA - ASC TERT1 [nTPM]":"19.9","Cell RNA - BEWO [nTPM]":"178.0","Cell RNA - BJ [nTPM]":"14.8","Cell RNA - BJ hTERT+ [nTPM]":"40.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"28.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"34.9","Cell RNA - CACO-2 [nTPM]":"19.7","Cell RNA - CAPAN-2 [nTPM]":"52.9","Cell RNA - Daudi [nTPM]":"16.0","Cell RNA - EFO-21 [nTPM]":"45.8","Cell RNA - fHDF\/TERT166 [nTPM]":"24.8","Cell RNA - GAMG [nTPM]":"52.0","Cell RNA - HaCaT [nTPM]":"23.5","Cell RNA - HAP1 [nTPM]":"25.8","Cell RNA - HBEC3-KT [nTPM]":"24.7","Cell RNA - HBF TERT88 [nTPM]":"12.9","Cell RNA - HDLM-2 [nTPM]":"38.0","Cell RNA - HEK 293 [nTPM]":"38.5","Cell RNA - HEL [nTPM]":"15.6","Cell RNA - HeLa [nTPM]":"24.1","Cell RNA - Hep G2 [nTPM]":"60.6","Cell RNA - HHSteC [nTPM]":"60.5","Cell RNA - HL-60 [nTPM]":"23.3","Cell RNA - HMC-1 [nTPM]":"64.7","Cell RNA - HSkMC [nTPM]":"28.0","Cell RNA - hTCEpi [nTPM]":"66.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.9","Cell RNA - hTERT-HME1 [nTPM]":"14.7","Cell RNA - hTERT-RPE1 [nTPM]":"26.3","Cell RNA - HUVEC TERT2 [nTPM]":"32.9","Cell RNA - JURKAT [nTPM]":"24.9","Cell RNA - K-562 [nTPM]":"30.9","Cell RNA - Karpas-707 [nTPM]":"55.0","Cell RNA - LHCN-M2 [nTPM]":"28.8","Cell RNA - MCF7 [nTPM]":"61.9","Cell RNA - MOLT-4 [nTPM]":"20.7","Cell RNA - NB-4 [nTPM]":"45.1","Cell RNA - NTERA-2 [nTPM]":"21.8","Cell RNA - OE19 [nTPM]":"35.3","Cell RNA - PC-3 [nTPM]":"26.0","Cell RNA - REH [nTPM]":"37.2","Cell RNA - RH-30 [nTPM]":"13.4","Cell RNA - RPMI-8226 [nTPM]":"54.5","Cell RNA - RPTEC TERT1 [nTPM]":"30.2","Cell RNA - RT4 [nTPM]":"53.0","Cell RNA - SCLC-21H [nTPM]":"20.8","Cell RNA - SH-SY5Y [nTPM]":"19.6","Cell RNA - SiHa [nTPM]":"5.7","Cell RNA - SK-BR-3 [nTPM]":"186.5","Cell RNA - SK-MEL-30 [nTPM]":"18.3","Cell RNA - SuSa [nTPM]":"14.0","Cell RNA - T-47d [nTPM]":"62.2","Cell RNA - THP-1 [nTPM]":"32.4","Cell RNA - TIME [nTPM]":"20.2","Cell RNA - U-138 MG [nTPM]":"19.2","Cell RNA - U-2 OS [nTPM]":"10.1","Cell RNA - U-2197 [nTPM]":"24.9","Cell RNA - U-251 MG [nTPM]":"22.5","Cell RNA - U-266\/70 [nTPM]":"58.3","Cell RNA - U-266\/84 [nTPM]":"64.2","Cell RNA - U-698 [nTPM]":"15.9","Cell RNA - U-87 MG [nTPM]":"28.4","Cell RNA - U-937 [nTPM]":"47.3","Cell RNA - WM-115 [nTPM]":"11.9","Blood RNA - basophil [nTPM]":"63.4","Blood RNA - classical monocyte [nTPM]":"59.8","Blood RNA - eosinophil [nTPM]":"98.4","Blood RNA - gdT-cell [nTPM]":"57.6","Blood RNA - intermediate monocyte [nTPM]":"47.6","Blood RNA - MAIT T-cell [nTPM]":"42.7","Blood RNA - memory B-cell [nTPM]":"24.3","Blood RNA - memory CD4 T-cell [nTPM]":"43.6","Blood RNA - memory CD8 T-cell [nTPM]":"53.6","Blood RNA - myeloid DC [nTPM]":"63.8","Blood RNA - naive B-cell [nTPM]":"29.3","Blood RNA - naive CD4 T-cell [nTPM]":"38.3","Blood RNA - naive CD8 T-cell [nTPM]":"40.6","Blood RNA - neutrophil [nTPM]":"23.8","Blood RNA - NK-cell [nTPM]":"41.2","Blood RNA - non-classical monocyte [nTPM]":"38.7","Blood RNA - plasmacytoid DC [nTPM]":"68.1","Blood RNA - T-reg [nTPM]":"53.5","Blood RNA - total PBMC [nTPM]":"46.6","Brain RNA - amygdala [nTPM]":"13.1","Brain RNA - basal ganglia [nTPM]":"14.2","Brain RNA - cerebellum [nTPM]":"14.2","Brain RNA - cerebral cortex [nTPM]":"16.0","Brain RNA - hippocampal formation [nTPM]":"13.2","Brain RNA - hypothalamus [nTPM]":"13.6","Brain RNA - medulla oblongata [nTPM]":"14.6","Brain RNA - midbrain [nTPM]":"13.6","Brain RNA - pons [nTPM]":"15.1","Brain RNA - spinal cord [nTPM]":"13.5","Brain RNA - thalamus [nTPM]":"15.6","Brain RNA - white matter [nTPM]":"17.1","Single Cell Type RNA - Adipocytes [nTPM]":"1.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.9","Single Cell Type RNA - Astrocytes [nTPM]":"11.1","Single Cell Type RNA - B-cells [nTPM]":"10.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.9","Single Cell Type RNA - Bipolar cells [nTPM]":"10.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"6.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"315.9","Single Cell Type RNA - dendritic cells [nTPM]":"25.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"46.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.3","Single Cell Type RNA - Endothelial cells [nTPM]":"11.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.0","Single Cell Type RNA - Erythroid cells [nTPM]":"17.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"106.9","Single Cell Type RNA - Fibroblasts [nTPM]":"9.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.6","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"7.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.0","Single Cell Type RNA - Hepatocytes [nTPM]":"39.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"70.1","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"39.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"36.7","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"2.5","Single Cell Type RNA - Leydig cells [nTPM]":"19.0","Single Cell Type RNA - Macrophages [nTPM]":"17.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"17.5","Single Cell Type RNA - Muller glia cells [nTPM]":"25.0","Single Cell Type RNA - NK-cells [nTPM]":"40.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.5","Single Cell Type RNA - Paneth cells [nTPM]":"43.7","Single Cell Type RNA - Peritubular cells [nTPM]":"12.4","Single Cell Type RNA - Plasma cells [nTPM]":"13.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"53.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.5","Single Cell Type RNA - Spermatocytes [nTPM]":"3.2","Single Cell Type RNA - Spermatogonia [nTPM]":"8.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"451.4","Single Cell Type RNA - T-cells [nTPM]":"15.9","Single Cell Type RNA - Theca cells [nTPM]":"3.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"50.2","Single Cell Type RNA - Urothelial cells [nTPM]":"13.3"},{"Gene":"CLN6","Gene synonym":["FLJ20561","HsT18960","nclf"],"Ensembl":"ENSG00000128973","Gene description":"CLN6 transmembrane ER protein","Uniprot":["Q9NWW5"],"Chromosome":"15","Position":"68206992-68257211","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration","Neuronal ceroid lipofuscinosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"181.8","Hofbauer cells":"88.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066046","HPA066759"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Endoplasmic reticulum","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Nucleoli","Vesicles"],"Antibody RRID":{"HPA066046":"AB_2685604","HPA066759":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.87e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.6","Tissue RNA - adrenal gland [nTPM]":"17.6","Tissue RNA - amygdala [nTPM]":"12.7","Tissue RNA - appendix [nTPM]":"14.8","Tissue RNA - basal ganglia [nTPM]":"13.0","Tissue RNA - bone marrow [nTPM]":"29.9","Tissue RNA - breast [nTPM]":"11.5","Tissue RNA - cerebellum [nTPM]":"13.3","Tissue RNA - cerebral cortex [nTPM]":"14.9","Tissue RNA - cervix [nTPM]":"11.0","Tissue RNA - choroid plexus [nTPM]":"13.2","Tissue RNA - colon [nTPM]":"17.5","Tissue RNA - duodenum [nTPM]":"14.6","Tissue RNA - endometrium 1 [nTPM]":"9.8","Tissue RNA - epididymis [nTPM]":"6.8","Tissue RNA - esophagus [nTPM]":"16.9","Tissue RNA - fallopian tube [nTPM]":"9.8","Tissue RNA - gallbladder [nTPM]":"9.6","Tissue RNA - heart muscle [nTPM]":"9.3","Tissue RNA - hippocampal formation [nTPM]":"12.1","Tissue RNA - hypothalamus [nTPM]":"12.6","Tissue RNA - kidney [nTPM]":"20.0","Tissue RNA - liver [nTPM]":"22.7","Tissue RNA - lung [nTPM]":"13.2","Tissue RNA - lymph node [nTPM]":"16.2","Tissue RNA - medulla oblongata [nTPM]":"13.3","Tissue RNA - midbrain [nTPM]":"13.1","Tissue RNA - ovary [nTPM]":"6.8","Tissue RNA - pancreas [nTPM]":"19.1","Tissue RNA - parathyroid gland [nTPM]":"10.4","Tissue RNA - pituitary gland [nTPM]":"10.1","Tissue RNA - placenta [nTPM]":"11.6","Tissue RNA - pons [nTPM]":"13.8","Tissue RNA - prostate [nTPM]":"12.4","Tissue RNA - rectum [nTPM]":"14.9","Tissue RNA - retina [nTPM]":"11.8","Tissue RNA - salivary gland [nTPM]":"14.8","Tissue RNA - seminal vesicle [nTPM]":"9.2","Tissue RNA - skeletal muscle [nTPM]":"17.0","Tissue RNA - skin 1 [nTPM]":"14.7","Tissue RNA - small intestine [nTPM]":"14.6","Tissue RNA - smooth muscle [nTPM]":"10.4","Tissue RNA - spinal cord [nTPM]":"12.8","Tissue RNA - spleen [nTPM]":"20.7","Tissue RNA - stomach 1 [nTPM]":"13.3","Tissue RNA - testis [nTPM]":"10.9","Tissue RNA - thalamus [nTPM]":"13.0","Tissue RNA - thymus [nTPM]":"11.6","Tissue RNA - thyroid gland [nTPM]":"12.9","Tissue RNA - tongue [nTPM]":"7.3","Tissue RNA - tonsil [nTPM]":"16.7","Tissue RNA - urinary bladder [nTPM]":"10.7","Tissue RNA - vagina [nTPM]":"9.6","Tissue RNA - white matter [nTPM]":"14.5","Cell RNA - A-431 [nTPM]":"38.2","Cell RNA - A549 [nTPM]":"93.1","Cell RNA - AF22 [nTPM]":"23.9","Cell RNA - AN3-CA [nTPM]":"33.9","Cell RNA - ASC diff [nTPM]":"14.5","Cell RNA - ASC TERT1 [nTPM]":"11.8","Cell RNA - BEWO [nTPM]":"57.1","Cell RNA - BJ [nTPM]":"35.3","Cell RNA - BJ hTERT+ [nTPM]":"17.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"42.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"34.9","Cell RNA - CACO-2 [nTPM]":"72.1","Cell RNA - CAPAN-2 [nTPM]":"60.5","Cell RNA - Daudi [nTPM]":"57.6","Cell RNA - EFO-21 [nTPM]":"17.2","Cell RNA - fHDF\/TERT166 [nTPM]":"21.4","Cell RNA - GAMG [nTPM]":"31.7","Cell RNA - HaCaT [nTPM]":"69.5","Cell RNA - HAP1 [nTPM]":"69.8","Cell RNA - HBEC3-KT [nTPM]":"34.5","Cell RNA - HBF TERT88 [nTPM]":"17.0","Cell RNA - HDLM-2 [nTPM]":"38.5","Cell RNA - HEK 293 [nTPM]":"82.3","Cell RNA - HEL [nTPM]":"84.3","Cell RNA - HeLa [nTPM]":"66.1","Cell RNA - Hep G2 [nTPM]":"54.3","Cell RNA - HHSteC [nTPM]":"29.7","Cell RNA - HL-60 [nTPM]":"95.6","Cell RNA - HMC-1 [nTPM]":"58.1","Cell RNA - HSkMC [nTPM]":"20.8","Cell RNA - hTCEpi [nTPM]":"11.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"34.7","Cell RNA - hTERT-HME1 [nTPM]":"23.7","Cell RNA - hTERT-RPE1 [nTPM]":"9.0","Cell RNA - HUVEC TERT2 [nTPM]":"29.1","Cell RNA - JURKAT [nTPM]":"33.1","Cell RNA - K-562 [nTPM]":"56.9","Cell RNA - Karpas-707 [nTPM]":"116.0","Cell RNA - LHCN-M2 [nTPM]":"33.6","Cell RNA - MCF7 [nTPM]":"103.8","Cell RNA - MOLT-4 [nTPM]":"44.0","Cell RNA - NB-4 [nTPM]":"69.4","Cell RNA - NTERA-2 [nTPM]":"57.1","Cell RNA - OE19 [nTPM]":"67.3","Cell RNA - PC-3 [nTPM]":"38.3","Cell RNA - REH [nTPM]":"42.1","Cell RNA - RH-30 [nTPM]":"71.8","Cell RNA - RPMI-8226 [nTPM]":"80.6","Cell RNA - RPTEC TERT1 [nTPM]":"36.2","Cell RNA - RT4 [nTPM]":"97.0","Cell RNA - SCLC-21H [nTPM]":"48.2","Cell RNA - SH-SY5Y [nTPM]":"20.0","Cell RNA - SiHa [nTPM]":"39.5","Cell RNA - SK-BR-3 [nTPM]":"61.7","Cell RNA - SK-MEL-30 [nTPM]":"34.3","Cell RNA - SuSa [nTPM]":"18.0","Cell RNA - T-47d [nTPM]":"33.1","Cell RNA - THP-1 [nTPM]":"95.5","Cell RNA - TIME [nTPM]":"19.3","Cell RNA - U-138 MG [nTPM]":"48.1","Cell RNA - U-2 OS [nTPM]":"55.7","Cell RNA - U-2197 [nTPM]":"35.8","Cell RNA - U-251 MG [nTPM]":"127.2","Cell RNA - U-266\/70 [nTPM]":"81.3","Cell RNA - U-266\/84 [nTPM]":"97.3","Cell RNA - U-698 [nTPM]":"47.4","Cell RNA - U-87 MG [nTPM]":"30.0","Cell RNA - U-937 [nTPM]":"115.4","Cell RNA - WM-115 [nTPM]":"47.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"8.8","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"3.0","Blood RNA - intermediate monocyte [nTPM]":"13.0","Blood RNA - MAIT T-cell [nTPM]":"4.0","Blood RNA - memory B-cell [nTPM]":"2.9","Blood RNA - memory CD4 T-cell [nTPM]":"2.2","Blood RNA - memory CD8 T-cell [nTPM]":"4.3","Blood RNA - myeloid DC [nTPM]":"5.2","Blood RNA - naive B-cell [nTPM]":"2.3","Blood RNA - naive CD4 T-cell [nTPM]":"2.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.3","Blood RNA - neutrophil [nTPM]":"10.5","Blood RNA - NK-cell [nTPM]":"2.0","Blood RNA - non-classical monocyte [nTPM]":"16.1","Blood RNA - plasmacytoid DC [nTPM]":"4.4","Blood RNA - T-reg [nTPM]":"2.3","Blood RNA - total PBMC [nTPM]":"3.5","Brain RNA - amygdala [nTPM]":"12.7","Brain RNA - basal ganglia [nTPM]":"13.0","Brain RNA - cerebellum [nTPM]":"13.3","Brain RNA - cerebral cortex [nTPM]":"14.9","Brain RNA - hippocampal formation [nTPM]":"12.1","Brain RNA - hypothalamus [nTPM]":"12.6","Brain RNA - medulla oblongata [nTPM]":"13.3","Brain RNA - midbrain [nTPM]":"13.1","Brain RNA - pons [nTPM]":"13.8","Brain RNA - spinal cord [nTPM]":"12.8","Brain RNA - thalamus [nTPM]":"13.0","Brain RNA - white matter [nTPM]":"14.5","Single Cell Type RNA - Adipocytes [nTPM]":"1.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.9","Single Cell Type RNA - Astrocytes [nTPM]":"7.2","Single Cell Type RNA - B-cells [nTPM]":"13.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"181.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"27.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"9.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"42.8","Single Cell Type RNA - dendritic cells [nTPM]":"7.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"22.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.8","Single Cell Type RNA - Endothelial cells [nTPM]":"9.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.1","Single Cell Type RNA - Erythroid cells [nTPM]":"32.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"58.4","Single Cell Type RNA - Fibroblasts [nTPM]":"9.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.4","Single Cell Type RNA - granulocytes [nTPM]":"8.9","Single Cell Type RNA - Granulosa cells [nTPM]":"5.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"21.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"88.4","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.5","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"24.2","Single Cell Type RNA - Langerhans cells [nTPM]":"14.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"9.0","Single Cell Type RNA - Macrophages [nTPM]":"11.3","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"12.9","Single Cell Type RNA - Muller glia cells [nTPM]":"16.9","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.6","Single Cell Type RNA - Paneth cells [nTPM]":"26.0","Single Cell Type RNA - Peritubular cells [nTPM]":"8.2","Single Cell Type RNA - Plasma cells [nTPM]":"33.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"32.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.6","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"19.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"21.8","Single Cell Type RNA - T-cells [nTPM]":"9.5","Single Cell Type RNA - Theca cells [nTPM]":"5.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"35.6","Single Cell Type RNA - Urothelial cells [nTPM]":"16.3"},{"Gene":"CLP1","Gene synonym":["hClp1","HEAB"],"Ensembl":"ENSG00000172409","Gene description":"Cleavage factor polyribonucleotide kinase subunit 1","Uniprot":["Q92989"],"Chromosome":"11","Position":"57648188-57661865","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["mRNA processing","tRNA processing"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"32.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057770"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA057770":"AB_2683523"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Tissue RNA - adipose tissue [nTPM]":"8.9","Tissue RNA - adrenal gland [nTPM]":"7.4","Tissue RNA - amygdala [nTPM]":"3.1","Tissue RNA - appendix [nTPM]":"10.1","Tissue RNA - basal ganglia [nTPM]":"3.6","Tissue RNA - bone marrow [nTPM]":"26.1","Tissue RNA - breast [nTPM]":"9.2","Tissue RNA - cerebellum [nTPM]":"3.9","Tissue RNA - cerebral cortex [nTPM]":"4.4","Tissue RNA - cervix [nTPM]":"7.1","Tissue RNA - choroid plexus [nTPM]":"4.4","Tissue RNA - colon [nTPM]":"9.0","Tissue RNA - duodenum [nTPM]":"8.7","Tissue RNA - endometrium 1 [nTPM]":"7.7","Tissue RNA - epididymis [nTPM]":"7.6","Tissue RNA - esophagus [nTPM]":"9.2","Tissue RNA - fallopian tube [nTPM]":"7.3","Tissue RNA - gallbladder [nTPM]":"5.9","Tissue RNA - heart muscle [nTPM]":"6.5","Tissue RNA - hippocampal formation [nTPM]":"3.3","Tissue RNA - hypothalamus [nTPM]":"3.3","Tissue RNA - kidney [nTPM]":"8.0","Tissue RNA - liver [nTPM]":"10.1","Tissue RNA - lung [nTPM]":"7.3","Tissue RNA - lymph node [nTPM]":"10.8","Tissue RNA - medulla oblongata [nTPM]":"3.3","Tissue RNA - midbrain [nTPM]":"3.1","Tissue RNA - ovary [nTPM]":"6.8","Tissue RNA - pancreas [nTPM]":"7.4","Tissue RNA - parathyroid gland [nTPM]":"6.8","Tissue RNA - pituitary gland [nTPM]":"4.4","Tissue RNA - placenta [nTPM]":"9.2","Tissue RNA - pons [nTPM]":"3.7","Tissue RNA - prostate [nTPM]":"5.6","Tissue RNA - rectum [nTPM]":"8.6","Tissue RNA - retina [nTPM]":"3.2","Tissue RNA - salivary gland [nTPM]":"6.7","Tissue RNA - seminal vesicle [nTPM]":"7.1","Tissue RNA - skeletal muscle [nTPM]":"8.2","Tissue RNA - skin 1 [nTPM]":"9.0","Tissue RNA - small intestine [nTPM]":"8.4","Tissue RNA - smooth muscle [nTPM]":"8.9","Tissue RNA - spinal cord [nTPM]":"3.4","Tissue RNA - spleen [nTPM]":"10.0","Tissue RNA - stomach 1 [nTPM]":"8.1","Tissue RNA - testis [nTPM]":"8.4","Tissue RNA - thalamus [nTPM]":"3.3","Tissue RNA - thymus [nTPM]":"11.2","Tissue RNA - thyroid gland [nTPM]":"7.2","Tissue RNA - tongue [nTPM]":"9.3","Tissue RNA - tonsil [nTPM]":"13.1","Tissue RNA - urinary bladder [nTPM]":"8.6","Tissue RNA - vagina [nTPM]":"5.0","Tissue RNA - white matter [nTPM]":"3.7","Cell RNA - A-431 [nTPM]":"21.2","Cell RNA - A549 [nTPM]":"22.2","Cell RNA - AF22 [nTPM]":"21.0","Cell RNA - AN3-CA [nTPM]":"21.6","Cell RNA - ASC diff [nTPM]":"22.3","Cell RNA - ASC TERT1 [nTPM]":"14.4","Cell RNA - BEWO [nTPM]":"19.7","Cell RNA - BJ [nTPM]":"21.4","Cell RNA - BJ hTERT+ [nTPM]":"23.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"30.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"25.8","Cell RNA - CACO-2 [nTPM]":"21.4","Cell RNA - CAPAN-2 [nTPM]":"18.4","Cell RNA - Daudi [nTPM]":"35.1","Cell RNA - EFO-21 [nTPM]":"24.3","Cell RNA - fHDF\/TERT166 [nTPM]":"18.9","Cell RNA - GAMG [nTPM]":"24.2","Cell RNA - HaCaT [nTPM]":"25.9","Cell RNA - HAP1 [nTPM]":"29.2","Cell RNA - HBEC3-KT [nTPM]":"34.5","Cell RNA - HBF TERT88 [nTPM]":"34.2","Cell RNA - HDLM-2 [nTPM]":"24.3","Cell RNA - HEK 293 [nTPM]":"18.0","Cell RNA - HEL [nTPM]":"19.4","Cell RNA - HeLa [nTPM]":"13.5","Cell RNA - Hep G2 [nTPM]":"21.7","Cell RNA - HHSteC [nTPM]":"17.7","Cell RNA - HL-60 [nTPM]":"28.5","Cell RNA - HMC-1 [nTPM]":"22.2","Cell RNA - HSkMC [nTPM]":"17.4","Cell RNA - hTCEpi [nTPM]":"24.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.9","Cell RNA - hTERT-HME1 [nTPM]":"18.6","Cell RNA - hTERT-RPE1 [nTPM]":"11.9","Cell RNA - HUVEC TERT2 [nTPM]":"27.7","Cell RNA - JURKAT [nTPM]":"17.4","Cell RNA - K-562 [nTPM]":"30.4","Cell RNA - Karpas-707 [nTPM]":"11.9","Cell RNA - LHCN-M2 [nTPM]":"24.9","Cell RNA - MCF7 [nTPM]":"14.8","Cell RNA - MOLT-4 [nTPM]":"21.8","Cell RNA - NB-4 [nTPM]":"32.9","Cell RNA - NTERA-2 [nTPM]":"31.8","Cell RNA - OE19 [nTPM]":"24.3","Cell RNA - PC-3 [nTPM]":"22.2","Cell RNA - REH [nTPM]":"21.7","Cell RNA - RH-30 [nTPM]":"32.1","Cell RNA - RPMI-8226 [nTPM]":"37.5","Cell RNA - RPTEC TERT1 [nTPM]":"16.5","Cell RNA - RT4 [nTPM]":"15.0","Cell RNA - SCLC-21H [nTPM]":"11.1","Cell RNA - SH-SY5Y [nTPM]":"22.3","Cell RNA - SiHa [nTPM]":"19.1","Cell RNA - SK-BR-3 [nTPM]":"17.2","Cell RNA - SK-MEL-30 [nTPM]":"28.7","Cell RNA - SuSa [nTPM]":"21.7","Cell RNA - T-47d [nTPM]":"32.7","Cell RNA - THP-1 [nTPM]":"23.2","Cell RNA - TIME [nTPM]":"20.0","Cell RNA - U-138 MG [nTPM]":"16.0","Cell RNA - U-2 OS [nTPM]":"21.7","Cell RNA - U-2197 [nTPM]":"27.7","Cell RNA - U-251 MG [nTPM]":"15.9","Cell RNA - U-266\/70 [nTPM]":"18.6","Cell RNA - U-266\/84 [nTPM]":"26.4","Cell RNA - U-698 [nTPM]":"39.3","Cell RNA - U-87 MG [nTPM]":"17.3","Cell RNA - U-937 [nTPM]":"16.3","Cell RNA - WM-115 [nTPM]":"17.3","Blood RNA - basophil [nTPM]":"31.2","Blood RNA - classical monocyte [nTPM]":"19.0","Blood RNA - eosinophil [nTPM]":"20.0","Blood RNA - gdT-cell [nTPM]":"15.9","Blood RNA - intermediate monocyte [nTPM]":"16.4","Blood RNA - MAIT T-cell [nTPM]":"18.9","Blood RNA - memory B-cell [nTPM]":"15.6","Blood RNA - memory CD4 T-cell [nTPM]":"14.1","Blood RNA - memory CD8 T-cell [nTPM]":"16.4","Blood RNA - myeloid DC [nTPM]":"19.0","Blood RNA - naive B-cell [nTPM]":"14.3","Blood RNA - naive CD4 T-cell [nTPM]":"16.4","Blood RNA - naive CD8 T-cell [nTPM]":"14.9","Blood RNA - neutrophil [nTPM]":"21.7","Blood RNA - NK-cell [nTPM]":"13.6","Blood RNA - non-classical monocyte [nTPM]":"15.9","Blood RNA - plasmacytoid DC [nTPM]":"10.8","Blood RNA - T-reg [nTPM]":"16.2","Blood RNA - total PBMC [nTPM]":"12.3","Brain RNA - amygdala [nTPM]":"3.1","Brain RNA - basal ganglia [nTPM]":"3.6","Brain RNA - cerebellum [nTPM]":"3.9","Brain RNA - cerebral cortex [nTPM]":"4.4","Brain RNA - hippocampal formation [nTPM]":"3.3","Brain RNA - hypothalamus [nTPM]":"3.3","Brain RNA - medulla oblongata [nTPM]":"3.3","Brain RNA - midbrain [nTPM]":"3.1","Brain RNA - pons [nTPM]":"3.7","Brain RNA - spinal cord [nTPM]":"3.4","Brain RNA - thalamus [nTPM]":"3.3","Brain RNA - white matter [nTPM]":"3.7","Single Cell Type RNA - Adipocytes [nTPM]":"6.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.1","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"8.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"19.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"16.5","Single Cell Type RNA - Bipolar cells [nTPM]":"4.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"10.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.5","Single Cell Type RNA - dendritic cells [nTPM]":"12.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"12.9","Single Cell Type RNA - Early spermatids [nTPM]":"32.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.7","Single Cell Type RNA - Endothelial cells [nTPM]":"7.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"12.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.9","Single Cell Type RNA - Fibroblasts [nTPM]":"7.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.1","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"4.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.2","Single Cell Type RNA - Hepatocytes [nTPM]":"3.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.0","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.2","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"6.0","Single Cell Type RNA - Langerhans cells [nTPM]":"6.9","Single Cell Type RNA - Late spermatids [nTPM]":"4.1","Single Cell Type RNA - Leydig cells [nTPM]":"5.6","Single Cell Type RNA - Macrophages [nTPM]":"5.8","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"15.0","Single Cell Type RNA - Muller glia cells [nTPM]":"3.3","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.8","Single Cell Type RNA - Paneth cells [nTPM]":"4.7","Single Cell Type RNA - Peritubular cells [nTPM]":"8.6","Single Cell Type RNA - Plasma cells [nTPM]":"5.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.9","Single Cell Type RNA - Spermatocytes [nTPM]":"9.4","Single Cell Type RNA - Spermatogonia [nTPM]":"12.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"13.5","Single Cell Type RNA - T-cells [nTPM]":"9.7","Single Cell Type RNA - Theca cells [nTPM]":"6.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.6","Single Cell Type RNA - Urothelial cells [nTPM]":"7.8"},{"Gene":"CLPP","Gene synonym":[],"Ensembl":"ENSG00000125656","Gene description":"Caseinolytic mitochondrial matrix peptidase proteolytic subunit","Uniprot":["Q16740"],"Chromosome":"19","Position":"6361531-6370242","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Deafness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"229.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010649"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"8500","Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA010649":"AB_1078538"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.50e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-3"},"Tissue RNA - adipose tissue [nTPM]":"48.6","Tissue RNA - adrenal gland [nTPM]":"65.8","Tissue RNA - amygdala [nTPM]":"52.0","Tissue RNA - appendix [nTPM]":"41.5","Tissue RNA - basal ganglia [nTPM]":"51.5","Tissue RNA - bone marrow [nTPM]":"42.9","Tissue RNA - breast [nTPM]":"45.1","Tissue RNA - cerebellum [nTPM]":"52.2","Tissue RNA - cerebral cortex [nTPM]":"63.8","Tissue RNA - cervix [nTPM]":"39.1","Tissue RNA - choroid plexus [nTPM]":"58.0","Tissue RNA - colon [nTPM]":"46.6","Tissue RNA - duodenum [nTPM]":"47.4","Tissue RNA - endometrium 1 [nTPM]":"41.1","Tissue RNA - epididymis [nTPM]":"17.8","Tissue RNA - esophagus [nTPM]":"56.1","Tissue RNA - fallopian tube [nTPM]":"40.1","Tissue RNA - gallbladder [nTPM]":"20.8","Tissue RNA - heart muscle [nTPM]":"78.0","Tissue RNA - hippocampal formation [nTPM]":"50.9","Tissue RNA - hypothalamus [nTPM]":"52.7","Tissue RNA - kidney [nTPM]":"60.5","Tissue RNA - liver [nTPM]":"90.7","Tissue RNA - lung [nTPM]":"39.7","Tissue RNA - lymph node [nTPM]":"47.7","Tissue RNA - medulla oblongata [nTPM]":"52.8","Tissue RNA - midbrain [nTPM]":"52.4","Tissue RNA - ovary [nTPM]":"38.5","Tissue RNA - pancreas [nTPM]":"53.6","Tissue RNA - parathyroid gland [nTPM]":"36.6","Tissue RNA - pituitary gland [nTPM]":"44.5","Tissue RNA - placenta [nTPM]":"25.4","Tissue RNA - pons [nTPM]":"49.5","Tissue RNA - prostate [nTPM]":"41.0","Tissue RNA - rectum [nTPM]":"22.9","Tissue RNA - retina [nTPM]":"15.6","Tissue RNA - salivary gland [nTPM]":"48.3","Tissue RNA - seminal vesicle [nTPM]":"31.2","Tissue RNA - skeletal muscle [nTPM]":"146.8","Tissue RNA - skin 1 [nTPM]":"47.5","Tissue RNA - small intestine [nTPM]":"43.6","Tissue RNA - smooth muscle [nTPM]":"25.1","Tissue RNA - spinal cord [nTPM]":"51.8","Tissue RNA - spleen [nTPM]":"45.6","Tissue RNA - stomach 1 [nTPM]":"55.6","Tissue RNA - testis [nTPM]":"45.2","Tissue RNA - thalamus [nTPM]":"54.5","Tissue RNA - thymus [nTPM]":"45.2","Tissue RNA - thyroid gland [nTPM]":"36.1","Tissue RNA - tongue [nTPM]":"59.3","Tissue RNA - tonsil [nTPM]":"35.6","Tissue RNA - urinary bladder [nTPM]":"44.6","Tissue RNA - vagina [nTPM]":"37.9","Tissue RNA - white matter [nTPM]":"53.9","Cell RNA - A-431 [nTPM]":"146.7","Cell RNA - A549 [nTPM]":"98.2","Cell RNA - AF22 [nTPM]":"61.2","Cell RNA - AN3-CA [nTPM]":"113.9","Cell RNA - ASC diff [nTPM]":"38.7","Cell RNA - ASC TERT1 [nTPM]":"54.8","Cell RNA - BEWO [nTPM]":"62.4","Cell RNA - BJ [nTPM]":"76.9","Cell RNA - BJ hTERT+ [nTPM]":"59.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"112.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"102.5","Cell RNA - CACO-2 [nTPM]":"87.2","Cell RNA - CAPAN-2 [nTPM]":"48.9","Cell RNA - Daudi [nTPM]":"124.1","Cell RNA - EFO-21 [nTPM]":"122.8","Cell RNA - fHDF\/TERT166 [nTPM]":"61.3","Cell RNA - GAMG [nTPM]":"61.1","Cell RNA - HaCaT [nTPM]":"83.1","Cell RNA - HAP1 [nTPM]":"63.5","Cell RNA - HBEC3-KT [nTPM]":"109.1","Cell RNA - HBF TERT88 [nTPM]":"38.5","Cell RNA - HDLM-2 [nTPM]":"133.8","Cell RNA - HEK 293 [nTPM]":"189.3","Cell RNA - HEL [nTPM]":"95.8","Cell RNA - HeLa [nTPM]":"82.2","Cell RNA - Hep G2 [nTPM]":"122.9","Cell RNA - HHSteC [nTPM]":"106.6","Cell RNA - HL-60 [nTPM]":"90.7","Cell RNA - HMC-1 [nTPM]":"129.8","Cell RNA - HSkMC [nTPM]":"73.4","Cell RNA - hTCEpi [nTPM]":"74.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"78.9","Cell RNA - hTERT-HME1 [nTPM]":"82.9","Cell RNA - hTERT-RPE1 [nTPM]":"69.7","Cell RNA - HUVEC TERT2 [nTPM]":"113.9","Cell RNA - JURKAT [nTPM]":"188.5","Cell RNA - K-562 [nTPM]":"97.5","Cell RNA - Karpas-707 [nTPM]":"174.5","Cell RNA - LHCN-M2 [nTPM]":"72.3","Cell RNA - MCF7 [nTPM]":"192.8","Cell RNA - MOLT-4 [nTPM]":"153.1","Cell RNA - NB-4 [nTPM]":"104.5","Cell RNA - NTERA-2 [nTPM]":"93.2","Cell RNA - OE19 [nTPM]":"100.6","Cell RNA - PC-3 [nTPM]":"207.8","Cell RNA - REH [nTPM]":"108.6","Cell RNA - RH-30 [nTPM]":"73.2","Cell RNA - RPMI-8226 [nTPM]":"206.2","Cell RNA - RPTEC TERT1 [nTPM]":"81.2","Cell RNA - RT4 [nTPM]":"79.4","Cell RNA - SCLC-21H [nTPM]":"99.3","Cell RNA - SH-SY5Y [nTPM]":"95.9","Cell RNA - SiHa [nTPM]":"48.9","Cell RNA - SK-BR-3 [nTPM]":"123.8","Cell RNA - SK-MEL-30 [nTPM]":"133.0","Cell RNA - SuSa [nTPM]":"36.7","Cell RNA - T-47d [nTPM]":"67.3","Cell RNA - THP-1 [nTPM]":"130.6","Cell RNA - TIME [nTPM]":"76.9","Cell RNA - U-138 MG [nTPM]":"70.5","Cell RNA - U-2 OS [nTPM]":"69.7","Cell RNA - U-2197 [nTPM]":"180.7","Cell RNA - U-251 MG [nTPM]":"156.0","Cell RNA - U-266\/70 [nTPM]":"235.4","Cell RNA - U-266\/84 [nTPM]":"225.3","Cell RNA - U-698 [nTPM]":"137.2","Cell RNA - U-87 MG [nTPM]":"103.5","Cell RNA - U-937 [nTPM]":"132.9","Cell RNA - WM-115 [nTPM]":"117.3","Blood RNA - basophil [nTPM]":"29.4","Blood RNA - classical monocyte [nTPM]":"82.6","Blood RNA - eosinophil [nTPM]":"47.8","Blood RNA - gdT-cell [nTPM]":"112.0","Blood RNA - intermediate monocyte [nTPM]":"79.6","Blood RNA - MAIT T-cell [nTPM]":"133.5","Blood RNA - memory B-cell [nTPM]":"119.5","Blood RNA - memory CD4 T-cell [nTPM]":"159.4","Blood RNA - memory CD8 T-cell [nTPM]":"139.6","Blood RNA - myeloid DC [nTPM]":"102.4","Blood RNA - naive B-cell [nTPM]":"131.5","Blood RNA - naive CD4 T-cell [nTPM]":"138.4","Blood RNA - naive CD8 T-cell [nTPM]":"137.4","Blood RNA - neutrophil [nTPM]":"62.1","Blood RNA - NK-cell [nTPM]":"126.5","Blood RNA - non-classical monocyte [nTPM]":"55.5","Blood RNA - plasmacytoid DC [nTPM]":"155.5","Blood RNA - T-reg [nTPM]":"207.2","Blood RNA - total PBMC [nTPM]":"162.6","Brain RNA - amygdala [nTPM]":"52.0","Brain RNA - basal ganglia [nTPM]":"51.5","Brain RNA - cerebellum [nTPM]":"52.2","Brain RNA - cerebral cortex [nTPM]":"63.8","Brain RNA - hippocampal formation [nTPM]":"50.9","Brain RNA - hypothalamus [nTPM]":"52.7","Brain RNA - medulla oblongata [nTPM]":"52.8","Brain RNA - midbrain [nTPM]":"52.4","Brain RNA - pons [nTPM]":"49.5","Brain RNA - spinal cord [nTPM]":"51.8","Brain RNA - thalamus [nTPM]":"54.5","Brain RNA - white matter [nTPM]":"53.9","Single Cell Type RNA - Adipocytes [nTPM]":"39.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"35.2","Single Cell Type RNA - Astrocytes [nTPM]":"8.1","Single Cell Type RNA - B-cells [nTPM]":"45.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"44.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"59.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"90.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"38.1","Single Cell Type RNA - Bipolar cells [nTPM]":"31.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"47.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"57.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"45.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"55.8","Single Cell Type RNA - Club cells [nTPM]":"46.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"72.2","Single Cell Type RNA - dendritic cells [nTPM]":"43.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"56.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"144.8","Single Cell Type RNA - Ductal cells [nTPM]":"88.8","Single Cell Type RNA - Early spermatids [nTPM]":"105.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"43.1","Single Cell Type RNA - Endothelial cells [nTPM]":"51.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"35.3","Single Cell Type RNA - Erythroid cells [nTPM]":"54.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"96.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"113.6","Single Cell Type RNA - Fibroblasts [nTPM]":"42.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"36.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"35.0","Single Cell Type RNA - granulocytes [nTPM]":"26.0","Single Cell Type RNA - Granulosa cells [nTPM]":"63.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"61.8","Single Cell Type RNA - Hepatocytes [nTPM]":"89.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"81.3","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"50.9","Single Cell Type RNA - Ionocytes [nTPM]":"54.9","Single Cell Type RNA - Kupffer cells [nTPM]":"38.9","Single Cell Type RNA - Langerhans cells [nTPM]":"35.0","Single Cell Type RNA - Late spermatids [nTPM]":"229.8","Single Cell Type RNA - Leydig cells [nTPM]":"42.6","Single Cell Type RNA - Macrophages [nTPM]":"38.7","Single Cell Type RNA - Melanocytes [nTPM]":"55.2","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"70.6","Single Cell Type RNA - Muller glia cells [nTPM]":"46.6","Single Cell Type RNA - NK-cells [nTPM]":"46.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"101.9","Single Cell Type RNA - Paneth cells [nTPM]":"67.7","Single Cell Type RNA - Peritubular cells [nTPM]":"43.2","Single Cell Type RNA - Plasma cells [nTPM]":"82.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"89.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"110.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"189.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"44.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"79.9","Single Cell Type RNA - Spermatocytes [nTPM]":"67.7","Single Cell Type RNA - Spermatogonia [nTPM]":"48.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"56.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"37.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"57.7","Single Cell Type RNA - T-cells [nTPM]":"65.3","Single Cell Type RNA - Theca cells [nTPM]":"95.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"65.4","Single Cell Type RNA - Urothelial cells [nTPM]":"65.4"},{"Gene":"CLRN1","Gene synonym":["RP61","USH3","USH3A"],"Ensembl":"ENSG00000163646","Gene description":"Clarin 1","Uniprot":["P58418"],"Chromosome":"3","Position":"150926163-150972727","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Hearing","Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Retinitis pigmentosa","Usher syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"adrenal gland":"4.9","retina":"12.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Muller glia cells":"165.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"30","RNA cell line specific nTPM":{"NTERA-2":"3.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 5: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-3"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"4.9","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"1.3","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"12.8","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"3.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"165.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CLTC","Gene synonym":["CLTCL2","Hc"],"Ensembl":"ENSG00000141367","Gene description":"Clathrin heavy chain","Uniprot":["Q00610"],"Chromosome":"17","Position":"59619689-59696956","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Autophagy","Cell cycle","Cell division","Mitosis"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010389","CAB011571","CAB017155","HPA059143"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles","Endosomes","Lysosomes","Mitotic spindle","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"14000000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Vesicles","Endosomes","Lysosomes"],"Subcellular additional location":["Mitotic spindle","Cytosol"],"Antibody RRID":{"CAB010389":"AB_2083184","CAB011571":"AB_2083165","CAB017155":null,"HPA059143":"AB_2683924"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.35e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.65e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.54e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.02e-4"},"Tissue RNA - adipose tissue [nTPM]":"105.4","Tissue RNA - adrenal gland [nTPM]":"95.2","Tissue RNA - amygdala [nTPM]":"42.1","Tissue RNA - appendix [nTPM]":"89.7","Tissue RNA - basal ganglia [nTPM]":"54.9","Tissue RNA - bone marrow [nTPM]":"96.3","Tissue RNA - breast [nTPM]":"81.6","Tissue RNA - cerebellum [nTPM]":"67.3","Tissue RNA - cerebral cortex [nTPM]":"103.9","Tissue RNA - cervix [nTPM]":"92.3","Tissue RNA - choroid plexus [nTPM]":"36.7","Tissue RNA - colon [nTPM]":"121.7","Tissue RNA - duodenum [nTPM]":"74.1","Tissue RNA - endometrium 1 [nTPM]":"83.1","Tissue RNA - epididymis [nTPM]":"126.4","Tissue RNA - esophagus [nTPM]":"82.1","Tissue RNA - fallopian tube [nTPM]":"67.8","Tissue RNA - gallbladder [nTPM]":"88.9","Tissue RNA - heart muscle [nTPM]":"90.7","Tissue RNA - hippocampal formation [nTPM]":"60.7","Tissue RNA - hypothalamus [nTPM]":"65.1","Tissue RNA - kidney [nTPM]":"125.5","Tissue RNA - liver [nTPM]":"117.7","Tissue RNA - lung [nTPM]":"82.1","Tissue RNA - lymph node [nTPM]":"75.5","Tissue RNA - medulla oblongata [nTPM]":"95.5","Tissue RNA - midbrain [nTPM]":"52.4","Tissue RNA - ovary [nTPM]":"73.2","Tissue RNA - pancreas [nTPM]":"56.8","Tissue RNA - parathyroid gland [nTPM]":"186.8","Tissue RNA - pituitary gland [nTPM]":"51.6","Tissue RNA - placenta [nTPM]":"139.6","Tissue RNA - pons [nTPM]":"95.2","Tissue RNA - prostate [nTPM]":"97.8","Tissue RNA - rectum [nTPM]":"128.3","Tissue RNA - retina [nTPM]":"163.6","Tissue RNA - salivary gland [nTPM]":"68.6","Tissue RNA - seminal vesicle [nTPM]":"104.2","Tissue RNA - skeletal muscle [nTPM]":"88.4","Tissue RNA - skin 1 [nTPM]":"81.3","Tissue RNA - small intestine [nTPM]":"73.3","Tissue RNA - smooth muscle [nTPM]":"121.0","Tissue RNA - spinal cord [nTPM]":"43.8","Tissue RNA - spleen [nTPM]":"78.8","Tissue RNA - stomach 1 [nTPM]":"91.2","Tissue RNA - testis [nTPM]":"71.3","Tissue RNA - thalamus [nTPM]":"68.2","Tissue RNA - thymus [nTPM]":"76.0","Tissue RNA - thyroid gland [nTPM]":"114.1","Tissue RNA - tongue [nTPM]":"83.9","Tissue RNA - tonsil [nTPM]":"86.8","Tissue RNA - urinary bladder [nTPM]":"101.1","Tissue RNA - vagina [nTPM]":"51.6","Tissue RNA - white matter [nTPM]":"55.0","Cell RNA - A-431 [nTPM]":"293.3","Cell RNA - A549 [nTPM]":"426.1","Cell RNA - AF22 [nTPM]":"207.6","Cell RNA - AN3-CA [nTPM]":"207.0","Cell RNA - ASC diff [nTPM]":"345.8","Cell RNA - ASC TERT1 [nTPM]":"280.5","Cell RNA - BEWO [nTPM]":"240.0","Cell RNA - BJ [nTPM]":"305.7","Cell RNA - BJ hTERT+ [nTPM]":"321.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"268.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"278.9","Cell RNA - CACO-2 [nTPM]":"264.7","Cell RNA - CAPAN-2 [nTPM]":"175.2","Cell RNA - Daudi [nTPM]":"200.6","Cell RNA - EFO-21 [nTPM]":"340.1","Cell RNA - fHDF\/TERT166 [nTPM]":"436.4","Cell RNA - GAMG [nTPM]":"296.9","Cell RNA - HaCaT [nTPM]":"186.2","Cell RNA - HAP1 [nTPM]":"313.6","Cell RNA - HBEC3-KT [nTPM]":"255.1","Cell RNA - HBF TERT88 [nTPM]":"356.2","Cell RNA - HDLM-2 [nTPM]":"214.4","Cell RNA - HEK 293 [nTPM]":"166.8","Cell RNA - HEL [nTPM]":"328.2","Cell RNA - HeLa [nTPM]":"248.8","Cell RNA - Hep G2 [nTPM]":"414.0","Cell RNA - HHSteC [nTPM]":"262.3","Cell RNA - HL-60 [nTPM]":"228.5","Cell RNA - HMC-1 [nTPM]":"182.3","Cell RNA - HSkMC [nTPM]":"266.9","Cell RNA - hTCEpi [nTPM]":"154.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"408.0","Cell RNA - hTERT-HME1 [nTPM]":"262.3","Cell RNA - hTERT-RPE1 [nTPM]":"211.4","Cell RNA - HUVEC TERT2 [nTPM]":"302.0","Cell RNA - JURKAT [nTPM]":"99.9","Cell RNA - K-562 [nTPM]":"334.4","Cell RNA - Karpas-707 [nTPM]":"280.4","Cell RNA - LHCN-M2 [nTPM]":"429.1","Cell RNA - MCF7 [nTPM]":"511.1","Cell RNA - MOLT-4 [nTPM]":"135.6","Cell RNA - NB-4 [nTPM]":"65.1","Cell RNA - NTERA-2 [nTPM]":"179.6","Cell RNA - OE19 [nTPM]":"263.3","Cell RNA - PC-3 [nTPM]":"248.2","Cell RNA - REH [nTPM]":"118.7","Cell RNA - RH-30 [nTPM]":"343.6","Cell RNA - RPMI-8226 [nTPM]":"244.9","Cell RNA - RPTEC TERT1 [nTPM]":"297.5","Cell RNA - RT4 [nTPM]":"404.1","Cell RNA - SCLC-21H [nTPM]":"184.1","Cell RNA - SH-SY5Y [nTPM]":"216.7","Cell RNA - SiHa [nTPM]":"188.3","Cell RNA - SK-BR-3 [nTPM]":"122.9","Cell RNA - SK-MEL-30 [nTPM]":"180.4","Cell RNA - SuSa [nTPM]":"270.5","Cell RNA - T-47d [nTPM]":"290.3","Cell RNA - THP-1 [nTPM]":"142.3","Cell RNA - TIME [nTPM]":"385.6","Cell RNA - U-138 MG [nTPM]":"492.4","Cell RNA - U-2 OS [nTPM]":"287.9","Cell RNA - U-2197 [nTPM]":"237.0","Cell RNA - U-251 MG [nTPM]":"317.8","Cell RNA - U-266\/70 [nTPM]":"213.3","Cell RNA - U-266\/84 [nTPM]":"320.3","Cell RNA - U-698 [nTPM]":"181.4","Cell RNA - U-87 MG [nTPM]":"357.7","Cell RNA - U-937 [nTPM]":"151.6","Cell RNA - WM-115 [nTPM]":"305.3","Blood RNA - basophil [nTPM]":"16.6","Blood RNA - classical monocyte [nTPM]":"33.1","Blood RNA - eosinophil [nTPM]":"21.3","Blood RNA - gdT-cell [nTPM]":"17.5","Blood RNA - intermediate monocyte [nTPM]":"36.3","Blood RNA - MAIT T-cell [nTPM]":"21.7","Blood RNA - memory B-cell [nTPM]":"13.7","Blood RNA - memory CD4 T-cell [nTPM]":"16.1","Blood RNA - memory CD8 T-cell [nTPM]":"19.2","Blood RNA - myeloid DC [nTPM]":"36.5","Blood RNA - naive B-cell [nTPM]":"12.9","Blood RNA - naive CD4 T-cell [nTPM]":"13.4","Blood RNA - naive CD8 T-cell [nTPM]":"15.0","Blood RNA - neutrophil [nTPM]":"19.9","Blood RNA - NK-cell [nTPM]":"18.9","Blood RNA - non-classical monocyte [nTPM]":"32.5","Blood RNA - plasmacytoid DC [nTPM]":"22.8","Blood RNA - T-reg [nTPM]":"22.1","Blood RNA - total PBMC [nTPM]":"23.3","Brain RNA - amygdala [nTPM]":"42.1","Brain RNA - basal ganglia [nTPM]":"54.9","Brain RNA - cerebellum [nTPM]":"67.3","Brain RNA - cerebral cortex [nTPM]":"103.9","Brain RNA - hippocampal formation [nTPM]":"60.7","Brain RNA - hypothalamus [nTPM]":"65.1","Brain RNA - medulla oblongata [nTPM]":"95.5","Brain RNA - midbrain [nTPM]":"52.4","Brain RNA - pons [nTPM]":"95.2","Brain RNA - spinal cord [nTPM]":"43.8","Brain RNA - thalamus [nTPM]":"68.2","Brain RNA - white matter [nTPM]":"55.0","Single Cell Type RNA - Adipocytes [nTPM]":"62.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"99.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"107.9","Single Cell Type RNA - Astrocytes [nTPM]":"80.3","Single Cell Type RNA - B-cells [nTPM]":"46.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"63.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"44.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"75.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"28.5","Single Cell Type RNA - Bipolar cells [nTPM]":"91.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"58.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"34.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"77.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"71.4","Single Cell Type RNA - Club cells [nTPM]":"103.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"77.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"60.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"109.1","Single Cell Type RNA - dendritic cells [nTPM]":"60.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"184.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"27.4","Single Cell Type RNA - Ductal cells [nTPM]":"76.2","Single Cell Type RNA - Early spermatids [nTPM]":"23.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"95.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"95.6","Single Cell Type RNA - Endothelial cells [nTPM]":"79.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"120.6","Single Cell Type RNA - Erythroid cells [nTPM]":"115.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"137.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"97.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"47.7","Single Cell Type RNA - Fibroblasts [nTPM]":"84.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"99.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"106.1","Single Cell Type RNA - granulocytes [nTPM]":"68.4","Single Cell Type RNA - Granulosa cells [nTPM]":"75.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"120.7","Single Cell Type RNA - Hepatocytes [nTPM]":"185.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"182.5","Single Cell Type RNA - Horizontal cells [nTPM]":"85.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"135.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"120.7","Single Cell Type RNA - Ionocytes [nTPM]":"77.3","Single Cell Type RNA - Kupffer cells [nTPM]":"195.0","Single Cell Type RNA - Langerhans cells [nTPM]":"93.2","Single Cell Type RNA - Late spermatids [nTPM]":"77.2","Single Cell Type RNA - Leydig cells [nTPM]":"74.0","Single Cell Type RNA - Macrophages [nTPM]":"128.3","Single Cell Type RNA - Melanocytes [nTPM]":"53.4","Single Cell Type RNA - Microglial cells [nTPM]":"79.6","Single Cell Type RNA - monocytes [nTPM]":"102.8","Single Cell Type RNA - Muller glia cells [nTPM]":"53.9","Single Cell Type RNA - NK-cells [nTPM]":"38.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"73.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"124.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"106.2","Single Cell Type RNA - Paneth cells [nTPM]":"76.1","Single Cell Type RNA - Peritubular cells [nTPM]":"93.6","Single Cell Type RNA - Plasma cells [nTPM]":"83.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"86.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"102.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"132.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"128.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"65.2","Single Cell Type RNA - Sertoli cells [nTPM]":"78.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"66.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"82.8","Single Cell Type RNA - Spermatocytes [nTPM]":"52.7","Single Cell Type RNA - Spermatogonia [nTPM]":"38.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"60.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"79.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"107.9","Single Cell Type RNA - T-cells [nTPM]":"45.9","Single Cell Type RNA - Theca cells [nTPM]":"81.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"127.8","Single Cell Type RNA - Urothelial cells [nTPM]":"91.6"},{"Gene":"CNGA1","Gene synonym":["CNCG","CNCG1","CNG1","RCNC1","RCNCa","RP49"],"Ensembl":"ENSG00000198515","Gene description":"Cyclic nucleotide gated channel subunit alpha 1","Uniprot":["P29973"],"Chromosome":"4","Position":"47935977-48016681","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Sensory transduction","Transport","Vision"],"Molecular function":["Ion channel","Ligand-gated ion channel"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"retina":"264.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Rod photoreceptor cells":"1139.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"urothelial cancer":"4.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"9.2","RT4":"7.2","U-2 OS":"3.0"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"1.0"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA076168"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA076168":"AB_2686781"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.3","Tissue RNA - adrenal gland [nTPM]":"0.4","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"0.8","Tissue RNA - basal ganglia [nTPM]":"1.4","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"1.5","Tissue RNA - cerebellum [nTPM]":"1.6","Tissue RNA - cerebral cortex [nTPM]":"0.9","Tissue RNA - cervix [nTPM]":"1.0","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"3.6","Tissue RNA - duodenum [nTPM]":"2.2","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"9.3","Tissue RNA - esophagus [nTPM]":"9.0","Tissue RNA - fallopian tube [nTPM]":"4.1","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"0.8","Tissue RNA - kidney [nTPM]":"2.4","Tissue RNA - liver [nTPM]":"23.5","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"4.1","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"1.0","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"2.6","Tissue RNA - rectum [nTPM]":"2.4","Tissue RNA - retina [nTPM]":"264.4","Tissue RNA - salivary gland [nTPM]":"4.3","Tissue RNA - seminal vesicle [nTPM]":"1.7","Tissue RNA - skeletal muscle [nTPM]":"5.0","Tissue RNA - skin 1 [nTPM]":"5.1","Tissue RNA - small intestine [nTPM]":"6.3","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"3.4","Tissue RNA - stomach 1 [nTPM]":"2.8","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"0.7","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"1.3","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"3.7","Tissue RNA - vagina [nTPM]":"1.9","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"2.3","Cell RNA - A549 [nTPM]":"0.9","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"2.0","Cell RNA - CAPAN-2 [nTPM]":"9.2","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"2.7","Cell RNA - HaCaT [nTPM]":"1.4","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.8","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.8","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.9","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"1.1","Cell RNA - PC-3 [nTPM]":"2.2","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.4","Cell RNA - RT4 [nTPM]":"7.2","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.9","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"3.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"0.8","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"1.4","Brain RNA - cerebellum [nTPM]":"1.6","Brain RNA - cerebral cortex [nTPM]":"0.9","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"0.8","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.7","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"7.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"97.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"3.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"62.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"91.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"10.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"8.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"38.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.7","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"163.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.1","Single Cell Type RNA - Paneth cells [nTPM]":"16.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1139.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.7","Single Cell Type RNA - Urothelial cells [nTPM]":"35.1"},{"Gene":"CNGA3","Gene synonym":["ACHM2","CCNC1","CCNCa","CNCG3","CNG3"],"Ensembl":"ENSG00000144191","Gene description":"Cyclic nucleotide gated channel subunit alpha 3","Uniprot":["Q16281"],"Chromosome":"2","Position":"98346188-98398601","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Sensory transduction","Transport","Vision"],"Molecular function":["Ion channel","Ligand-gated ion channel"],"Disease involvement":["Disease variant","Leber congenital amaurosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"5.7","intestine":"4.2","pituitary gland":"10.1","retina":"5.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"14","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"43.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"glioma":"7.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"U-87 MG":"6.8"},"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"6","RNA mouse brain regional specific nTPM":{"basal ganglia":"1.8","hypothalamus":"1.9"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049378","CAB079025"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Approved","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB079025":null,"HPA049378":"AB_2732551"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-4"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.6","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.8","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"2.9","Tissue RNA - colon [nTPM]":"4.2","Tissue RNA - duodenum [nTPM]":"1.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"1.5","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"5.6","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"3.4","Tissue RNA - midbrain [nTPM]":"1.5","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"10.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"3.6","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"1.1","Tissue RNA - retina [nTPM]":"5.9","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"1.3","Tissue RNA - smooth muscle [nTPM]":"0.8","Tissue RNA - spinal cord [nTPM]":"5.7","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.9","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"1.3","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.6","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"4.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.8","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"1.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"6.8","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.6","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.8","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"5.6","Brain RNA - medulla oblongata [nTPM]":"3.4","Brain RNA - midbrain [nTPM]":"1.5","Brain RNA - pons [nTPM]":"3.6","Brain RNA - spinal cord [nTPM]":"5.7","Brain RNA - thalamus [nTPM]":"1.3","Brain RNA - white matter [nTPM]":"4.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"43.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CNGB1","Gene synonym":["CNCG2","CNCG3L","CNGB1B","GAR1","GARP","RCNC2","RCNCb","RP45"],"Ensembl":"ENSG00000070729","Gene description":"Cyclic nucleotide gated channel subunit beta 1","Uniprot":["Q14028"],"Chromosome":"16","Position":"57882340-57971128","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Olfaction","Sensory transduction","Transport","Vision"],"Molecular function":["Ion channel","Ligand-gated ion channel"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"17","RNA tissue specific nTPM":{"retina":"600.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"331.5","Rod photoreceptor cells":"1111.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"head and neck cancer":"2.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"1.5","RPMI-8226":"1.8","SCLC-21H":"5.0","SiHa":"2.9","SK-BR-3":"1.4"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hypothalamus":"4.5"},"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039159","HPA060355"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA039159":"AB_10795579","HPA060355":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"2.5","Tissue RNA - amygdala [nTPM]":"15.5","Tissue RNA - appendix [nTPM]":"1.1","Tissue RNA - basal ganglia [nTPM]":"13.2","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"20.4","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.6","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"24.5","Tissue RNA - hypothalamus [nTPM]":"24.8","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"2.8","Tissue RNA - midbrain [nTPM]":"3.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.5","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"4.4","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"600.2","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.6","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"2.4","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"36.3","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.6","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"1.1","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"1.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"1.3","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.9","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.9","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.8","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.6","Cell RNA - SCLC-21H [nTPM]":"5.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"2.9","Cell RNA - SK-BR-3 [nTPM]":"1.4","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"15.5","Brain RNA - basal ganglia [nTPM]":"13.2","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"20.4","Brain RNA - hippocampal formation [nTPM]":"24.5","Brain RNA - hypothalamus [nTPM]":"24.8","Brain RNA - medulla oblongata [nTPM]":"2.8","Brain RNA - midbrain [nTPM]":"3.2","Brain RNA - pons [nTPM]":"4.4","Brain RNA - spinal cord [nTPM]":"2.4","Brain RNA - thalamus [nTPM]":"36.3","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"61.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"331.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.9","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"4.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.9","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.4","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"89.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"1.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1111.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"CNGB3","Gene synonym":["ACHM1","ACHM3","RMCH"],"Ensembl":"ENSG00000170289","Gene description":"Cyclic nucleotide gated channel subunit beta 3","Uniprot":["Q9NQW8"],"Chromosome":"8","Position":"86553977-86743675","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Sensory transduction","Transport","Vision"],"Molecular function":["Ion channel","Ligand-gated ion channel"],"Disease involvement":["Disease variant","Stargardt disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"4.1","retina":"13.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"158.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"14","RNA cell line specific nTPM":{"SCLC-21H":"18.9"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057244"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA057244":"AB_2683380"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"4.1","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"1.2","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"1.7","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"0.6","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"13.1","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"1.2","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"2.1","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"1.1","Cell RNA - Hep G2 [nTPM]":"0.8","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.3","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.5","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"1.0","Cell RNA - SCLC-21H [nTPM]":"18.9","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.7","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"1.2","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"158.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"1.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"5.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"11.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"1.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CNNM2","Gene synonym":["ACDP2"],"Ensembl":"ENSG00000148842","Gene description":"Cyclin and CBS domain divalent metal cation transport mediator 2","Uniprot":["Q9H8M5"],"Chromosome":"10","Position":"102918294-103090222","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Mental retardation","Primary hypomagnesemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"37.9","parathyroid gland":"31.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"60.1","Excitatory neurons":"112.6","Inhibitory neurons":"146.9","Oligodendrocyte precursor cells":"92.5","Oligodendrocytes":"92.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"NK-cell":"1.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"NK-cells":"1.5"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059954","HPA071631"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA059954":"AB_2684177","HPA071631":"AB_2686427"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.39e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.3","Tissue RNA - adrenal gland [nTPM]":"11.5","Tissue RNA - amygdala [nTPM]":"5.1","Tissue RNA - appendix [nTPM]":"2.3","Tissue RNA - basal ganglia [nTPM]":"5.5","Tissue RNA - bone marrow [nTPM]":"9.3","Tissue RNA - breast [nTPM]":"2.5","Tissue RNA - cerebellum [nTPM]":"7.9","Tissue RNA - cerebral cortex [nTPM]":"5.7","Tissue RNA - cervix [nTPM]":"3.7","Tissue RNA - choroid plexus [nTPM]":"37.9","Tissue RNA - colon [nTPM]":"7.0","Tissue RNA - duodenum [nTPM]":"3.8","Tissue RNA - endometrium 1 [nTPM]":"3.6","Tissue RNA - epididymis [nTPM]":"2.1","Tissue RNA - esophagus [nTPM]":"1.7","Tissue RNA - fallopian tube [nTPM]":"4.8","Tissue RNA - gallbladder [nTPM]":"4.1","Tissue RNA - heart muscle [nTPM]":"2.1","Tissue RNA - hippocampal formation [nTPM]":"4.2","Tissue RNA - hypothalamus [nTPM]":"3.3","Tissue RNA - kidney [nTPM]":"9.1","Tissue RNA - liver [nTPM]":"4.8","Tissue RNA - lung [nTPM]":"3.8","Tissue RNA - lymph node [nTPM]":"1.5","Tissue RNA - medulla oblongata [nTPM]":"4.9","Tissue RNA - midbrain [nTPM]":"4.8","Tissue RNA - ovary [nTPM]":"4.8","Tissue RNA - pancreas [nTPM]":"3.6","Tissue RNA - parathyroid gland [nTPM]":"31.6","Tissue RNA - pituitary gland [nTPM]":"5.7","Tissue RNA - placenta [nTPM]":"8.7","Tissue RNA - pons [nTPM]":"4.7","Tissue RNA - prostate [nTPM]":"2.7","Tissue RNA - rectum [nTPM]":"6.4","Tissue RNA - retina [nTPM]":"5.0","Tissue RNA - salivary gland [nTPM]":"3.0","Tissue RNA - seminal vesicle [nTPM]":"3.0","Tissue RNA - skeletal muscle [nTPM]":"1.6","Tissue RNA - skin 1 [nTPM]":"4.5","Tissue RNA - small intestine [nTPM]":"4.5","Tissue RNA - smooth muscle [nTPM]":"3.7","Tissue RNA - spinal cord [nTPM]":"1.8","Tissue RNA - spleen [nTPM]":"2.1","Tissue RNA - stomach 1 [nTPM]":"3.3","Tissue RNA - testis [nTPM]":"4.5","Tissue RNA - thalamus [nTPM]":"4.6","Tissue RNA - thymus [nTPM]":"1.8","Tissue RNA - thyroid gland [nTPM]":"5.6","Tissue RNA - tongue [nTPM]":"1.5","Tissue RNA - tonsil [nTPM]":"1.1","Tissue RNA - urinary bladder [nTPM]":"3.2","Tissue RNA - vagina [nTPM]":"2.9","Tissue RNA - white matter [nTPM]":"9.7","Cell RNA - A-431 [nTPM]":"5.0","Cell RNA - A549 [nTPM]":"8.1","Cell RNA - AF22 [nTPM]":"3.1","Cell RNA - AN3-CA [nTPM]":"8.5","Cell RNA - ASC diff [nTPM]":"7.8","Cell RNA - ASC TERT1 [nTPM]":"3.2","Cell RNA - BEWO [nTPM]":"8.6","Cell RNA - BJ [nTPM]":"2.3","Cell RNA - BJ hTERT+ [nTPM]":"9.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.9","Cell RNA - CACO-2 [nTPM]":"5.8","Cell RNA - CAPAN-2 [nTPM]":"4.3","Cell RNA - Daudi [nTPM]":"1.9","Cell RNA - EFO-21 [nTPM]":"3.5","Cell RNA - fHDF\/TERT166 [nTPM]":"3.4","Cell RNA - GAMG [nTPM]":"6.0","Cell RNA - HaCaT [nTPM]":"6.3","Cell RNA - HAP1 [nTPM]":"6.9","Cell RNA - HBEC3-KT [nTPM]":"4.6","Cell RNA - HBF TERT88 [nTPM]":"2.4","Cell RNA - HDLM-2 [nTPM]":"3.3","Cell RNA - HEK 293 [nTPM]":"12.1","Cell RNA - HEL [nTPM]":"2.8","Cell RNA - HeLa [nTPM]":"4.2","Cell RNA - Hep G2 [nTPM]":"11.8","Cell RNA - HHSteC [nTPM]":"4.6","Cell RNA - HL-60 [nTPM]":"2.0","Cell RNA - HMC-1 [nTPM]":"3.6","Cell RNA - HSkMC [nTPM]":"4.2","Cell RNA - hTCEpi [nTPM]":"6.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.2","Cell RNA - hTERT-HME1 [nTPM]":"10.7","Cell RNA - hTERT-RPE1 [nTPM]":"7.9","Cell RNA - HUVEC TERT2 [nTPM]":"1.9","Cell RNA - JURKAT [nTPM]":"5.5","Cell RNA - K-562 [nTPM]":"4.8","Cell RNA - Karpas-707 [nTPM]":"10.9","Cell RNA - LHCN-M2 [nTPM]":"1.8","Cell RNA - MCF7 [nTPM]":"8.6","Cell RNA - MOLT-4 [nTPM]":"2.3","Cell RNA - NB-4 [nTPM]":"2.2","Cell RNA - NTERA-2 [nTPM]":"5.1","Cell RNA - OE19 [nTPM]":"4.9","Cell RNA - PC-3 [nTPM]":"5.0","Cell RNA - REH [nTPM]":"5.5","Cell RNA - RH-30 [nTPM]":"4.0","Cell RNA - RPMI-8226 [nTPM]":"2.4","Cell RNA - RPTEC TERT1 [nTPM]":"2.4","Cell RNA - RT4 [nTPM]":"2.9","Cell RNA - SCLC-21H [nTPM]":"4.5","Cell RNA - SH-SY5Y [nTPM]":"5.8","Cell RNA - SiHa [nTPM]":"5.9","Cell RNA - SK-BR-3 [nTPM]":"1.3","Cell RNA - SK-MEL-30 [nTPM]":"6.3","Cell RNA - SuSa [nTPM]":"9.1","Cell RNA - T-47d [nTPM]":"10.4","Cell RNA - THP-1 [nTPM]":"3.7","Cell RNA - TIME [nTPM]":"1.6","Cell RNA - U-138 MG [nTPM]":"4.2","Cell RNA - U-2 OS [nTPM]":"6.2","Cell RNA - U-2197 [nTPM]":"3.0","Cell RNA - U-251 MG [nTPM]":"4.2","Cell RNA - U-266\/70 [nTPM]":"11.7","Cell RNA - U-266\/84 [nTPM]":"14.1","Cell RNA - U-698 [nTPM]":"3.6","Cell RNA - U-87 MG [nTPM]":"7.4","Cell RNA - U-937 [nTPM]":"6.6","Cell RNA - WM-115 [nTPM]":"1.7","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"5.1","Brain RNA - basal ganglia [nTPM]":"5.5","Brain RNA - cerebellum [nTPM]":"7.9","Brain RNA - cerebral cortex [nTPM]":"5.7","Brain RNA - hippocampal formation [nTPM]":"4.2","Brain RNA - hypothalamus [nTPM]":"3.3","Brain RNA - medulla oblongata [nTPM]":"4.9","Brain RNA - midbrain [nTPM]":"4.8","Brain RNA - pons [nTPM]":"4.7","Brain RNA - spinal cord [nTPM]":"1.8","Brain RNA - thalamus [nTPM]":"4.6","Brain RNA - white matter [nTPM]":"9.7","Single Cell Type RNA - Adipocytes [nTPM]":"3.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.4","Single Cell Type RNA - Astrocytes [nTPM]":"60.1","Single Cell Type RNA - B-cells [nTPM]":"7.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"16.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"5.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.8","Single Cell Type RNA - dendritic cells [nTPM]":"8.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"46.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.2","Single Cell Type RNA - Early spermatids [nTPM]":"10.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.2","Single Cell Type RNA - Endothelial cells [nTPM]":"4.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"6.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"112.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.4","Single Cell Type RNA - Fibroblasts [nTPM]":"6.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.4","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"13.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"6.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.8","Single Cell Type RNA - Horizontal cells [nTPM]":"32.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"146.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.2","Single Cell Type RNA - Langerhans cells [nTPM]":"2.5","Single Cell Type RNA - Late spermatids [nTPM]":"15.1","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"4.7","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"39.4","Single Cell Type RNA - monocytes [nTPM]":"2.3","Single Cell Type RNA - Muller glia cells [nTPM]":"7.0","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"92.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"92.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.3","Single Cell Type RNA - Paneth cells [nTPM]":"9.0","Single Cell Type RNA - Peritubular cells [nTPM]":"3.4","Single Cell Type RNA - Plasma cells [nTPM]":"6.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.8","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.7","Single Cell Type RNA - Spermatocytes [nTPM]":"15.5","Single Cell Type RNA - Spermatogonia [nTPM]":"6.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"39.8","Single Cell Type RNA - T-cells [nTPM]":"5.1","Single Cell Type RNA - Theca cells [nTPM]":"3.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.6","Single Cell Type RNA - Urothelial cells [nTPM]":"2.2"},{"Gene":"CNNM4","Gene synonym":["ACDP4","KIAA1592"],"Ensembl":"ENSG00000158158","Gene description":"Cyclin and CBS domain divalent metal cation transport mediator 4","Uniprot":["Q6P4Q7"],"Chromosome":"2","Position":"96760902-96811874","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Biomineralization","Ion transport","Sensory transduction","Transport","Vision"],"Molecular function":null,"Disease involvement":["Amelogenesis imperfecta","Cone-rod dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"38.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"112.6","Distal enterocytes":"103.4","Rod photoreceptor cells":"51.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SK-BR-3":"45.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017732"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Plasma membrane","Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Actin filaments"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA017732":"AB_1847395"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.95e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.14e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.75e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Tissue RNA - adipose tissue [nTPM]":"2.8","Tissue RNA - adrenal gland [nTPM]":"3.6","Tissue RNA - amygdala [nTPM]":"5.0","Tissue RNA - appendix [nTPM]":"6.1","Tissue RNA - basal ganglia [nTPM]":"6.8","Tissue RNA - bone marrow [nTPM]":"4.9","Tissue RNA - breast [nTPM]":"7.0","Tissue RNA - cerebellum [nTPM]":"11.2","Tissue RNA - cerebral cortex [nTPM]":"5.4","Tissue RNA - cervix [nTPM]":"5.8","Tissue RNA - choroid plexus [nTPM]":"2.8","Tissue RNA - colon [nTPM]":"32.4","Tissue RNA - duodenum [nTPM]":"6.2","Tissue RNA - endometrium 1 [nTPM]":"4.0","Tissue RNA - epididymis [nTPM]":"4.7","Tissue RNA - esophagus [nTPM]":"7.1","Tissue RNA - fallopian tube [nTPM]":"10.4","Tissue RNA - gallbladder [nTPM]":"4.4","Tissue RNA - heart muscle [nTPM]":"12.5","Tissue RNA - hippocampal formation [nTPM]":"4.9","Tissue RNA - hypothalamus [nTPM]":"4.4","Tissue RNA - kidney [nTPM]":"6.8","Tissue RNA - liver [nTPM]":"4.4","Tissue RNA - lung [nTPM]":"8.0","Tissue RNA - lymph node [nTPM]":"4.6","Tissue RNA - medulla oblongata [nTPM]":"4.1","Tissue RNA - midbrain [nTPM]":"4.5","Tissue RNA - ovary [nTPM]":"5.1","Tissue RNA - pancreas [nTPM]":"7.4","Tissue RNA - parathyroid gland [nTPM]":"6.3","Tissue RNA - pituitary gland [nTPM]":"9.1","Tissue RNA - placenta [nTPM]":"5.8","Tissue RNA - pons [nTPM]":"4.2","Tissue RNA - prostate [nTPM]":"5.7","Tissue RNA - rectum [nTPM]":"34.3","Tissue RNA - retina [nTPM]":"38.8","Tissue RNA - salivary gland [nTPM]":"6.8","Tissue RNA - seminal vesicle [nTPM]":"5.1","Tissue RNA - skeletal muscle [nTPM]":"24.8","Tissue RNA - skin 1 [nTPM]":"7.2","Tissue RNA - small intestine [nTPM]":"11.3","Tissue RNA - smooth muscle [nTPM]":"4.7","Tissue RNA - spinal cord [nTPM]":"3.5","Tissue RNA - spleen [nTPM]":"5.3","Tissue RNA - stomach 1 [nTPM]":"12.8","Tissue RNA - testis [nTPM]":"7.9","Tissue RNA - thalamus [nTPM]":"4.5","Tissue RNA - thymus [nTPM]":"3.5","Tissue RNA - thyroid gland [nTPM]":"9.5","Tissue RNA - tongue [nTPM]":"13.1","Tissue RNA - tonsil [nTPM]":"4.9","Tissue RNA - urinary bladder [nTPM]":"5.5","Tissue RNA - vagina [nTPM]":"6.4","Tissue RNA - white matter [nTPM]":"5.7","Cell RNA - A-431 [nTPM]":"11.1","Cell RNA - A549 [nTPM]":"7.2","Cell RNA - AF22 [nTPM]":"5.7","Cell RNA - AN3-CA [nTPM]":"10.5","Cell RNA - ASC diff [nTPM]":"5.8","Cell RNA - ASC TERT1 [nTPM]":"3.9","Cell RNA - BEWO [nTPM]":"15.6","Cell RNA - BJ [nTPM]":"4.8","Cell RNA - BJ hTERT+ [nTPM]":"6.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.3","Cell RNA - CACO-2 [nTPM]":"13.2","Cell RNA - CAPAN-2 [nTPM]":"11.8","Cell RNA - Daudi [nTPM]":"8.1","Cell RNA - EFO-21 [nTPM]":"13.5","Cell RNA - fHDF\/TERT166 [nTPM]":"5.0","Cell RNA - GAMG [nTPM]":"9.5","Cell RNA - HaCaT [nTPM]":"14.1","Cell RNA - HAP1 [nTPM]":"14.9","Cell RNA - HBEC3-KT [nTPM]":"8.1","Cell RNA - HBF TERT88 [nTPM]":"6.3","Cell RNA - HDLM-2 [nTPM]":"16.3","Cell RNA - HEK 293 [nTPM]":"11.7","Cell RNA - HEL [nTPM]":"6.4","Cell RNA - HeLa [nTPM]":"4.8","Cell RNA - Hep G2 [nTPM]":"7.2","Cell RNA - HHSteC [nTPM]":"8.1","Cell RNA - HL-60 [nTPM]":"3.1","Cell RNA - HMC-1 [nTPM]":"6.2","Cell RNA - HSkMC [nTPM]":"3.8","Cell RNA - hTCEpi [nTPM]":"10.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.0","Cell RNA - hTERT-HME1 [nTPM]":"6.6","Cell RNA - hTERT-RPE1 [nTPM]":"4.6","Cell RNA - HUVEC TERT2 [nTPM]":"3.8","Cell RNA - JURKAT [nTPM]":"8.0","Cell RNA - K-562 [nTPM]":"3.3","Cell RNA - Karpas-707 [nTPM]":"22.3","Cell RNA - LHCN-M2 [nTPM]":"3.6","Cell RNA - MCF7 [nTPM]":"15.7","Cell RNA - MOLT-4 [nTPM]":"6.6","Cell RNA - NB-4 [nTPM]":"4.5","Cell RNA - NTERA-2 [nTPM]":"7.5","Cell RNA - OE19 [nTPM]":"20.5","Cell RNA - PC-3 [nTPM]":"9.8","Cell RNA - REH [nTPM]":"9.7","Cell RNA - RH-30 [nTPM]":"2.6","Cell RNA - RPMI-8226 [nTPM]":"9.3","Cell RNA - RPTEC TERT1 [nTPM]":"6.9","Cell RNA - RT4 [nTPM]":"8.6","Cell RNA - SCLC-21H [nTPM]":"26.7","Cell RNA - SH-SY5Y [nTPM]":"8.0","Cell RNA - SiHa [nTPM]":"9.1","Cell RNA - SK-BR-3 [nTPM]":"45.7","Cell RNA - SK-MEL-30 [nTPM]":"6.8","Cell RNA - SuSa [nTPM]":"15.9","Cell RNA - T-47d [nTPM]":"22.3","Cell RNA - THP-1 [nTPM]":"5.3","Cell RNA - TIME [nTPM]":"3.4","Cell RNA - U-138 MG [nTPM]":"4.0","Cell RNA - U-2 OS [nTPM]":"8.9","Cell RNA - U-2197 [nTPM]":"8.8","Cell RNA - U-251 MG [nTPM]":"5.4","Cell RNA - U-266\/70 [nTPM]":"7.7","Cell RNA - U-266\/84 [nTPM]":"6.6","Cell RNA - U-698 [nTPM]":"4.0","Cell RNA - U-87 MG [nTPM]":"5.9","Cell RNA - U-937 [nTPM]":"6.1","Cell RNA - WM-115 [nTPM]":"7.2","Blood RNA - basophil [nTPM]":"1.2","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.7","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"5.0","Brain RNA - basal ganglia [nTPM]":"6.8","Brain RNA - cerebellum [nTPM]":"11.2","Brain RNA - cerebral cortex [nTPM]":"5.4","Brain RNA - hippocampal formation [nTPM]":"4.9","Brain RNA - hypothalamus [nTPM]":"4.4","Brain RNA - medulla oblongata [nTPM]":"4.1","Brain RNA - midbrain [nTPM]":"4.5","Brain RNA - pons [nTPM]":"4.2","Brain RNA - spinal cord [nTPM]":"3.5","Brain RNA - thalamus [nTPM]":"4.5","Brain RNA - white matter [nTPM]":"5.7","Single Cell Type RNA - Adipocytes [nTPM]":"4.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.7","Single Cell Type RNA - Astrocytes [nTPM]":"12.4","Single Cell Type RNA - B-cells [nTPM]":"6.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"43.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"11.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"112.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.4","Single Cell Type RNA - dendritic cells [nTPM]":"6.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"103.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.2","Single Cell Type RNA - Early spermatids [nTPM]":"4.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.4","Single Cell Type RNA - Endothelial cells [nTPM]":"4.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.1","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.7","Single Cell Type RNA - Fibroblasts [nTPM]":"3.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"5.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"3.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.3","Single Cell Type RNA - Horizontal cells [nTPM]":"33.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.4","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"5.4","Single Cell Type RNA - Langerhans cells [nTPM]":"4.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"5.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"2.3","Single Cell Type RNA - Muller glia cells [nTPM]":"8.3","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.2","Single Cell Type RNA - Paneth cells [nTPM]":"21.3","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"4.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"51.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.3","Single Cell Type RNA - Spermatocytes [nTPM]":"4.6","Single Cell Type RNA - Spermatogonia [nTPM]":"2.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.7","Single Cell Type RNA - T-cells [nTPM]":"5.4","Single Cell Type RNA - Theca cells [nTPM]":"6.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.5","Single Cell Type RNA - Urothelial cells [nTPM]":"6.1"},{"Gene":"CNTN2","Gene synonym":["AXT","TAG-1","TAX","TAX1"],"Ensembl":"ENSG00000184144","Gene description":"Contactin 2","Uniprot":["Q02246"],"Chromosome":"1","Position":"205042937-205078289","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins","Transporters"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"248.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Oligodendrocytes":"335.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"glioma":"6.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"NTERA-2":"3.9","SCLC-21H":"9.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001397","HPA012497"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in brain","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"58000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA001397":"AB_1847146","HPA012497":"AB_1847147"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"82.6","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"145.4","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"125.7","Tissue RNA - cerebral cortex [nTPM]":"112.4","Tissue RNA - cervix [nTPM]":"0.6","Tissue RNA - choroid plexus [nTPM]":"32.4","Tissue RNA - colon [nTPM]":"2.1","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.7","Tissue RNA - hippocampal formation [nTPM]":"85.2","Tissue RNA - hypothalamus [nTPM]":"96.6","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"161.6","Tissue RNA - midbrain [nTPM]":"128.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"8.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"139.8","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"1.2","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"0.9","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"110.1","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"6.1","Tissue RNA - thalamus [nTPM]":"125.7","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"248.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"1.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"3.9","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"9.5","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"82.6","Brain RNA - basal ganglia [nTPM]":"145.4","Brain RNA - cerebellum [nTPM]":"125.7","Brain RNA - cerebral cortex [nTPM]":"112.4","Brain RNA - hippocampal formation [nTPM]":"85.2","Brain RNA - hypothalamus [nTPM]":"96.6","Brain RNA - medulla oblongata [nTPM]":"161.6","Brain RNA - midbrain [nTPM]":"128.1","Brain RNA - pons [nTPM]":"139.8","Brain RNA - spinal cord [nTPM]":"110.1","Brain RNA - thalamus [nTPM]":"125.7","Brain RNA - white matter [nTPM]":"248.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"2.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.6","Single Cell Type RNA - Early spermatids [nTPM]":"13.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"16.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"29.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"335.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"3.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"COASY","Gene synonym":["DPCK","NBP","PPAT"],"Ensembl":"ENSG00000068120","Gene description":"Coenzyme A synthase","Uniprot":["Q13057"],"Chromosome":"17","Position":"42561467-42566277","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Coenzyme A biosynthesis"],"Molecular function":["Kinase","Multifunctional enzyme","Nucleotidyltransferase","Transferase"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022875","HPA022912","HPA023273"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"20000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA022875":"AB_1847066","HPA022912":"AB_1847067","HPA023273":"AB_1847068"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.15e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.54e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Tissue RNA - adipose tissue [nTPM]":"27.4","Tissue RNA - adrenal gland [nTPM]":"60.0","Tissue RNA - amygdala [nTPM]":"24.0","Tissue RNA - appendix [nTPM]":"23.1","Tissue RNA - basal ganglia [nTPM]":"24.0","Tissue RNA - bone marrow [nTPM]":"29.5","Tissue RNA - breast [nTPM]":"32.8","Tissue RNA - cerebellum [nTPM]":"24.7","Tissue RNA - cerebral cortex [nTPM]":"28.1","Tissue RNA - cervix [nTPM]":"27.6","Tissue RNA - choroid plexus [nTPM]":"26.7","Tissue RNA - colon [nTPM]":"35.6","Tissue RNA - duodenum [nTPM]":"43.3","Tissue RNA - endometrium 1 [nTPM]":"25.2","Tissue RNA - epididymis [nTPM]":"17.2","Tissue RNA - esophagus [nTPM]":"54.4","Tissue RNA - fallopian tube [nTPM]":"29.8","Tissue RNA - gallbladder [nTPM]":"16.9","Tissue RNA - heart muscle [nTPM]":"29.4","Tissue RNA - hippocampal formation [nTPM]":"25.4","Tissue RNA - hypothalamus [nTPM]":"23.9","Tissue RNA - kidney [nTPM]":"45.6","Tissue RNA - liver [nTPM]":"70.9","Tissue RNA - lung [nTPM]":"30.3","Tissue RNA - lymph node [nTPM]":"25.0","Tissue RNA - medulla oblongata [nTPM]":"27.8","Tissue RNA - midbrain [nTPM]":"24.7","Tissue RNA - ovary [nTPM]":"26.0","Tissue RNA - pancreas [nTPM]":"59.0","Tissue RNA - parathyroid gland [nTPM]":"39.0","Tissue RNA - pituitary gland [nTPM]":"30.3","Tissue RNA - placenta [nTPM]":"25.5","Tissue RNA - pons [nTPM]":"28.1","Tissue RNA - prostate [nTPM]":"32.4","Tissue RNA - rectum [nTPM]":"24.3","Tissue RNA - retina [nTPM]":"13.3","Tissue RNA - salivary gland [nTPM]":"58.5","Tissue RNA - seminal vesicle [nTPM]":"28.7","Tissue RNA - skeletal muscle [nTPM]":"38.6","Tissue RNA - skin 1 [nTPM]":"46.6","Tissue RNA - small intestine [nTPM]":"36.9","Tissue RNA - smooth muscle [nTPM]":"17.2","Tissue RNA - spinal cord [nTPM]":"23.8","Tissue RNA - spleen [nTPM]":"35.9","Tissue RNA - stomach 1 [nTPM]":"47.2","Tissue RNA - testis [nTPM]":"32.4","Tissue RNA - thalamus [nTPM]":"25.7","Tissue RNA - thymus [nTPM]":"27.6","Tissue RNA - thyroid gland [nTPM]":"39.0","Tissue RNA - tongue [nTPM]":"25.3","Tissue RNA - tonsil [nTPM]":"25.2","Tissue RNA - urinary bladder [nTPM]":"26.8","Tissue RNA - vagina [nTPM]":"31.1","Tissue RNA - white matter [nTPM]":"24.6","Cell RNA - A-431 [nTPM]":"94.2","Cell RNA - A549 [nTPM]":"149.1","Cell RNA - AF22 [nTPM]":"27.2","Cell RNA - AN3-CA [nTPM]":"55.2","Cell RNA - ASC diff [nTPM]":"55.5","Cell RNA - ASC TERT1 [nTPM]":"34.8","Cell RNA - BEWO [nTPM]":"89.2","Cell RNA - BJ [nTPM]":"38.3","Cell RNA - BJ hTERT+ [nTPM]":"52.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"65.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"46.5","Cell RNA - CACO-2 [nTPM]":"85.7","Cell RNA - CAPAN-2 [nTPM]":"89.2","Cell RNA - Daudi [nTPM]":"52.7","Cell RNA - EFO-21 [nTPM]":"65.6","Cell RNA - fHDF\/TERT166 [nTPM]":"50.4","Cell RNA - GAMG [nTPM]":"69.5","Cell RNA - HaCaT [nTPM]":"146.9","Cell RNA - HAP1 [nTPM]":"66.1","Cell RNA - HBEC3-KT [nTPM]":"81.4","Cell RNA - HBF TERT88 [nTPM]":"43.7","Cell RNA - HDLM-2 [nTPM]":"47.6","Cell RNA - HEK 293 [nTPM]":"122.2","Cell RNA - HEL [nTPM]":"52.5","Cell RNA - HeLa [nTPM]":"91.2","Cell RNA - Hep G2 [nTPM]":"140.9","Cell RNA - HHSteC [nTPM]":"70.2","Cell RNA - HL-60 [nTPM]":"56.4","Cell RNA - HMC-1 [nTPM]":"73.1","Cell RNA - HSkMC [nTPM]":"51.5","Cell RNA - hTCEpi [nTPM]":"97.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"62.4","Cell RNA - hTERT-HME1 [nTPM]":"66.6","Cell RNA - hTERT-RPE1 [nTPM]":"52.4","Cell RNA - HUVEC TERT2 [nTPM]":"63.2","Cell RNA - JURKAT [nTPM]":"70.5","Cell RNA - K-562 [nTPM]":"98.7","Cell RNA - Karpas-707 [nTPM]":"70.8","Cell RNA - LHCN-M2 [nTPM]":"46.6","Cell RNA - MCF7 [nTPM]":"59.2","Cell RNA - MOLT-4 [nTPM]":"71.5","Cell RNA - NB-4 [nTPM]":"87.2","Cell RNA - NTERA-2 [nTPM]":"36.7","Cell RNA - OE19 [nTPM]":"125.8","Cell RNA - PC-3 [nTPM]":"75.1","Cell RNA - REH [nTPM]":"39.1","Cell RNA - RH-30 [nTPM]":"93.5","Cell RNA - RPMI-8226 [nTPM]":"88.1","Cell RNA - RPTEC TERT1 [nTPM]":"89.9","Cell RNA - RT4 [nTPM]":"66.7","Cell RNA - SCLC-21H [nTPM]":"63.3","Cell RNA - SH-SY5Y [nTPM]":"50.1","Cell RNA - SiHa [nTPM]":"34.9","Cell RNA - SK-BR-3 [nTPM]":"37.3","Cell RNA - SK-MEL-30 [nTPM]":"75.4","Cell RNA - SuSa [nTPM]":"52.2","Cell RNA - T-47d [nTPM]":"158.0","Cell RNA - THP-1 [nTPM]":"70.4","Cell RNA - TIME [nTPM]":"41.6","Cell RNA - U-138 MG [nTPM]":"68.3","Cell RNA - U-2 OS [nTPM]":"62.3","Cell RNA - U-2197 [nTPM]":"52.4","Cell RNA - U-251 MG [nTPM]":"40.1","Cell RNA - U-266\/70 [nTPM]":"84.6","Cell RNA - U-266\/84 [nTPM]":"127.4","Cell RNA - U-698 [nTPM]":"31.0","Cell RNA - U-87 MG [nTPM]":"80.9","Cell RNA - U-937 [nTPM]":"55.3","Cell RNA - WM-115 [nTPM]":"47.5","Blood RNA - basophil [nTPM]":"23.3","Blood RNA - classical monocyte [nTPM]":"29.8","Blood RNA - eosinophil [nTPM]":"26.8","Blood RNA - gdT-cell [nTPM]":"19.7","Blood RNA - intermediate monocyte [nTPM]":"31.8","Blood RNA - MAIT T-cell [nTPM]":"20.5","Blood RNA - memory B-cell [nTPM]":"15.8","Blood RNA - memory CD4 T-cell [nTPM]":"15.8","Blood RNA - memory CD8 T-cell [nTPM]":"19.1","Blood RNA - myeloid DC [nTPM]":"33.6","Blood RNA - naive B-cell [nTPM]":"15.7","Blood RNA - naive CD4 T-cell [nTPM]":"15.7","Blood RNA - naive CD8 T-cell [nTPM]":"16.3","Blood RNA - neutrophil [nTPM]":"19.5","Blood RNA - NK-cell [nTPM]":"21.0","Blood RNA - non-classical monocyte [nTPM]":"22.5","Blood RNA - plasmacytoid DC [nTPM]":"23.6","Blood RNA - T-reg [nTPM]":"18.1","Blood RNA - total PBMC [nTPM]":"24.0","Brain RNA - amygdala [nTPM]":"24.0","Brain RNA - basal ganglia [nTPM]":"24.0","Brain RNA - cerebellum [nTPM]":"24.7","Brain RNA - cerebral cortex [nTPM]":"28.1","Brain RNA - hippocampal formation [nTPM]":"25.4","Brain RNA - hypothalamus [nTPM]":"23.9","Brain RNA - medulla oblongata [nTPM]":"27.8","Brain RNA - midbrain [nTPM]":"24.7","Brain RNA - pons [nTPM]":"28.1","Brain RNA - spinal cord [nTPM]":"23.8","Brain RNA - thalamus [nTPM]":"25.7","Brain RNA - white matter [nTPM]":"24.6","Single Cell Type RNA - Adipocytes [nTPM]":"15.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.8","Single Cell Type RNA - Astrocytes [nTPM]":"9.8","Single Cell Type RNA - B-cells [nTPM]":"24.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"49.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.6","Single Cell Type RNA - Bipolar cells [nTPM]":"17.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"38.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"22.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"22.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"40.0","Single Cell Type RNA - Club cells [nTPM]":"33.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"71.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"89.4","Single Cell Type RNA - dendritic cells [nTPM]":"21.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"53.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"44.8","Single Cell Type RNA - Early spermatids [nTPM]":"4.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"31.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.6","Single Cell Type RNA - Endothelial cells [nTPM]":"20.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.4","Single Cell Type RNA - Erythroid cells [nTPM]":"30.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"52.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"51.6","Single Cell Type RNA - Fibroblasts [nTPM]":"18.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"40.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"28.0","Single Cell Type RNA - granulocytes [nTPM]":"10.2","Single Cell Type RNA - Granulosa cells [nTPM]":"101.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.9","Single Cell Type RNA - Hepatocytes [nTPM]":"94.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"40.3","Single Cell Type RNA - Horizontal cells [nTPM]":"33.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"36.7","Single Cell Type RNA - Ionocytes [nTPM]":"42.7","Single Cell Type RNA - Kupffer cells [nTPM]":"23.6","Single Cell Type RNA - Langerhans cells [nTPM]":"16.1","Single Cell Type RNA - Late spermatids [nTPM]":"7.7","Single Cell Type RNA - Leydig cells [nTPM]":"14.9","Single Cell Type RNA - Macrophages [nTPM]":"19.9","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"36.2","Single Cell Type RNA - Muller glia cells [nTPM]":"29.4","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"38.9","Single Cell Type RNA - Paneth cells [nTPM]":"32.4","Single Cell Type RNA - Peritubular cells [nTPM]":"16.6","Single Cell Type RNA - Plasma cells [nTPM]":"25.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"31.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"66.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"94.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"36.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.0","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.6","Single Cell Type RNA - Spermatocytes [nTPM]":"46.7","Single Cell Type RNA - Spermatogonia [nTPM]":"31.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"33.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"77.2","Single Cell Type RNA - T-cells [nTPM]":"16.9","Single Cell Type RNA - Theca cells [nTPM]":"36.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"45.1","Single Cell Type RNA - Urothelial cells [nTPM]":"30.7"},{"Gene":"COCH","Gene synonym":["COCH-5B2","DFNA31","DFNA9"],"Ensembl":"ENSG00000100473","Gene description":"Cochlin","Uniprot":["O43405"],"Chromosome":"14","Position":"30874514-30895065","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins","Transporters"],"Biological process":["Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"pancreas":"502.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Exocrine glandular cells":"63.0","Horizontal cells":"84.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"basal ganglia":"71.3"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"12","RNA blood cell specific nTPM":{"memory B-cell":"38.3","naive B-cell":"17.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"17","RNA blood lineage specific nTPM":{"B-cells":"38.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEK 293":"95.7","Hep G2":"63.8","K-562":"129.1","NB-4":"105.5","SCLC-21H":"111.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"basal ganglia":"50.8"},"Antibody":["HPA065086"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"160000","Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA065086":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.2","Tissue RNA - adrenal gland [nTPM]":"3.7","Tissue RNA - amygdala [nTPM]":"7.3","Tissue RNA - appendix [nTPM]":"2.8","Tissue RNA - basal ganglia [nTPM]":"71.3","Tissue RNA - bone marrow [nTPM]":"4.0","Tissue RNA - breast [nTPM]":"3.4","Tissue RNA - cerebellum [nTPM]":"1.4","Tissue RNA - cerebral cortex [nTPM]":"20.9","Tissue RNA - cervix [nTPM]":"17.4","Tissue RNA - choroid plexus [nTPM]":"19.0","Tissue RNA - colon [nTPM]":"3.2","Tissue RNA - duodenum [nTPM]":"0.8","Tissue RNA - endometrium 1 [nTPM]":"0.6","Tissue RNA - epididymis [nTPM]":"2.2","Tissue RNA - esophagus [nTPM]":"0.9","Tissue RNA - fallopian tube [nTPM]":"6.2","Tissue RNA - gallbladder [nTPM]":"2.9","Tissue RNA - heart muscle [nTPM]":"1.9","Tissue RNA - hippocampal formation [nTPM]":"5.6","Tissue RNA - hypothalamus [nTPM]":"8.0","Tissue RNA - kidney [nTPM]":"5.2","Tissue RNA - liver [nTPM]":"0.5","Tissue RNA - lung [nTPM]":"0.6","Tissue RNA - lymph node [nTPM]":"11.0","Tissue RNA - medulla oblongata [nTPM]":"2.9","Tissue RNA - midbrain [nTPM]":"7.9","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"502.0","Tissue RNA - parathyroid gland [nTPM]":"3.4","Tissue RNA - pituitary gland [nTPM]":"10.1","Tissue RNA - placenta [nTPM]":"1.9","Tissue RNA - pons [nTPM]":"3.7","Tissue RNA - prostate [nTPM]":"48.3","Tissue RNA - rectum [nTPM]":"2.2","Tissue RNA - retina [nTPM]":"12.1","Tissue RNA - salivary gland [nTPM]":"3.6","Tissue RNA - seminal vesicle [nTPM]":"73.4","Tissue RNA - skeletal muscle [nTPM]":"1.3","Tissue RNA - skin 1 [nTPM]":"15.2","Tissue RNA - small intestine [nTPM]":"2.6","Tissue RNA - smooth muscle [nTPM]":"1.1","Tissue RNA - spinal cord [nTPM]":"6.2","Tissue RNA - spleen [nTPM]":"2.6","Tissue RNA - stomach 1 [nTPM]":"1.7","Tissue RNA - testis [nTPM]":"5.2","Tissue RNA - thalamus [nTPM]":"12.5","Tissue RNA - thymus [nTPM]":"1.3","Tissue RNA - thyroid gland [nTPM]":"1.3","Tissue RNA - tongue [nTPM]":"5.0","Tissue RNA - tonsil [nTPM]":"7.7","Tissue RNA - urinary bladder [nTPM]":"2.0","Tissue RNA - vagina [nTPM]":"23.0","Tissue RNA - white matter [nTPM]":"1.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"35.3","Cell RNA - AF22 [nTPM]":"3.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.6","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"21.8","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.1","Cell RNA - CACO-2 [nTPM]":"20.9","Cell RNA - CAPAN-2 [nTPM]":"1.2","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"1.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"1.3","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"22.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"10.6","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"95.7","Cell RNA - HEL [nTPM]":"18.1","Cell RNA - HeLa [nTPM]":"7.6","Cell RNA - Hep G2 [nTPM]":"63.8","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"1.8","Cell RNA - HMC-1 [nTPM]":"7.3","Cell RNA - HSkMC [nTPM]":"1.3","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.6","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"39.9","Cell RNA - K-562 [nTPM]":"129.1","Cell RNA - Karpas-707 [nTPM]":"5.1","Cell RNA - LHCN-M2 [nTPM]":"1.6","Cell RNA - MCF7 [nTPM]":"0.8","Cell RNA - MOLT-4 [nTPM]":"9.2","Cell RNA - NB-4 [nTPM]":"105.5","Cell RNA - NTERA-2 [nTPM]":"11.9","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"3.7","Cell RNA - REH [nTPM]":"26.7","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.9","Cell RNA - RPTEC TERT1 [nTPM]":"1.1","Cell RNA - RT4 [nTPM]":"3.4","Cell RNA - SCLC-21H [nTPM]":"111.8","Cell RNA - SH-SY5Y [nTPM]":"30.4","Cell RNA - SiHa [nTPM]":"2.6","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"12.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"48.7","Cell RNA - TIME [nTPM]":"0.9","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"5.7","Cell RNA - U-266\/84 [nTPM]":"15.8","Cell RNA - U-698 [nTPM]":"11.2","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"4.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"38.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"17.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"2.2","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"7.3","Brain RNA - basal ganglia [nTPM]":"71.3","Brain RNA - cerebellum [nTPM]":"1.4","Brain RNA - cerebral cortex [nTPM]":"20.9","Brain RNA - hippocampal formation [nTPM]":"5.6","Brain RNA - hypothalamus [nTPM]":"8.0","Brain RNA - medulla oblongata [nTPM]":"2.9","Brain RNA - midbrain [nTPM]":"7.9","Brain RNA - pons [nTPM]":"3.7","Brain RNA - spinal cord [nTPM]":"6.2","Brain RNA - thalamus [nTPM]":"12.5","Brain RNA - white matter [nTPM]":"1.7","Single Cell Type RNA - Adipocytes [nTPM]":"2.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"3.6","Single Cell Type RNA - B-cells [nTPM]":"13.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"19.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"2.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"0.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.5","Single Cell Type RNA - dendritic cells [nTPM]":"1.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.5","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.8","Single Cell Type RNA - Endothelial cells [nTPM]":"3.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.0","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"63.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.3","Single Cell Type RNA - Fibroblasts [nTPM]":"22.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"1.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"5.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.8","Single Cell Type RNA - Horizontal cells [nTPM]":"84.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"5.0","Single Cell Type RNA - Langerhans cells [nTPM]":"25.2","Single Cell Type RNA - Late spermatids [nTPM]":"2.0","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"2.4","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"2.8","Single Cell Type RNA - Muller glia cells [nTPM]":"14.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.7","Single Cell Type RNA - Paneth cells [nTPM]":"4.3","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"10.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.0","Single Cell Type RNA - Spermatocytes [nTPM]":"22.1","Single Cell Type RNA - Spermatogonia [nTPM]":"20.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.6","Single Cell Type RNA - T-cells [nTPM]":"3.3","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"1.7"},{"Gene":"COLGALT1","Gene synonym":["FLJ22329","GLT25D1"],"Ensembl":"ENSG00000130309","Gene description":"Collagen beta(1-O)galactosyltransferase 1","Uniprot":["Q8NBJ5"],"Chromosome":"19","Position":"17555649-17583162","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"76.2","Hofbauer cells":"91.0","Kupffer cells":"70.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047821"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9700","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 19: Lung - Lung function","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA047821":"AB_2680168"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.65e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.92e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.83e-4"},"Tissue RNA - adipose tissue [nTPM]":"38.6","Tissue RNA - adrenal gland [nTPM]":"14.3","Tissue RNA - amygdala [nTPM]":"5.9","Tissue RNA - appendix [nTPM]":"38.1","Tissue RNA - basal ganglia [nTPM]":"6.9","Tissue RNA - bone marrow [nTPM]":"32.9","Tissue RNA - breast [nTPM]":"27.5","Tissue RNA - cerebellum [nTPM]":"7.9","Tissue RNA - cerebral cortex [nTPM]":"8.4","Tissue RNA - cervix [nTPM]":"31.1","Tissue RNA - choroid plexus [nTPM]":"10.6","Tissue RNA - colon [nTPM]":"27.7","Tissue RNA - duodenum [nTPM]":"16.2","Tissue RNA - endometrium 1 [nTPM]":"28.4","Tissue RNA - epididymis [nTPM]":"4.4","Tissue RNA - esophagus [nTPM]":"17.9","Tissue RNA - fallopian tube [nTPM]":"26.5","Tissue RNA - gallbladder [nTPM]":"19.0","Tissue RNA - heart muscle [nTPM]":"22.4","Tissue RNA - hippocampal formation [nTPM]":"7.1","Tissue RNA - hypothalamus [nTPM]":"9.1","Tissue RNA - kidney [nTPM]":"12.7","Tissue RNA - liver [nTPM]":"16.3","Tissue RNA - lung [nTPM]":"34.9","Tissue RNA - lymph node [nTPM]":"29.7","Tissue RNA - medulla oblongata [nTPM]":"12.1","Tissue RNA - midbrain [nTPM]":"9.3","Tissue RNA - ovary [nTPM]":"23.5","Tissue RNA - pancreas [nTPM]":"15.8","Tissue RNA - parathyroid gland [nTPM]":"9.0","Tissue RNA - pituitary gland [nTPM]":"10.1","Tissue RNA - placenta [nTPM]":"40.9","Tissue RNA - pons [nTPM]":"12.3","Tissue RNA - prostate [nTPM]":"15.5","Tissue RNA - rectum [nTPM]":"15.2","Tissue RNA - retina [nTPM]":"3.2","Tissue RNA - salivary gland [nTPM]":"15.9","Tissue RNA - seminal vesicle [nTPM]":"16.3","Tissue RNA - skeletal muscle [nTPM]":"15.1","Tissue RNA - skin 1 [nTPM]":"23.9","Tissue RNA - small intestine [nTPM]":"24.7","Tissue RNA - smooth muscle [nTPM]":"35.4","Tissue RNA - spinal cord [nTPM]":"7.6","Tissue RNA - spleen [nTPM]":"39.5","Tissue RNA - stomach 1 [nTPM]":"18.2","Tissue RNA - testis [nTPM]":"11.9","Tissue RNA - thalamus [nTPM]":"18.9","Tissue RNA - thymus [nTPM]":"9.9","Tissue RNA - thyroid gland [nTPM]":"14.7","Tissue RNA - tongue [nTPM]":"7.5","Tissue RNA - tonsil [nTPM]":"15.8","Tissue RNA - urinary bladder [nTPM]":"28.1","Tissue RNA - vagina [nTPM]":"22.8","Tissue RNA - white matter [nTPM]":"12.6","Cell RNA - A-431 [nTPM]":"103.1","Cell RNA - A549 [nTPM]":"118.0","Cell RNA - AF22 [nTPM]":"56.7","Cell RNA - AN3-CA [nTPM]":"79.8","Cell RNA - ASC diff [nTPM]":"222.3","Cell RNA - ASC TERT1 [nTPM]":"136.3","Cell RNA - BEWO [nTPM]":"90.9","Cell RNA - BJ [nTPM]":"95.9","Cell RNA - BJ hTERT+ [nTPM]":"55.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"121.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"125.9","Cell RNA - CACO-2 [nTPM]":"90.4","Cell RNA - CAPAN-2 [nTPM]":"159.6","Cell RNA - Daudi [nTPM]":"53.0","Cell RNA - EFO-21 [nTPM]":"164.7","Cell RNA - fHDF\/TERT166 [nTPM]":"166.9","Cell RNA - GAMG [nTPM]":"104.2","Cell RNA - HaCaT [nTPM]":"91.5","Cell RNA - HAP1 [nTPM]":"58.4","Cell RNA - HBEC3-KT [nTPM]":"110.6","Cell RNA - HBF TERT88 [nTPM]":"73.4","Cell RNA - HDLM-2 [nTPM]":"29.5","Cell RNA - HEK 293 [nTPM]":"94.9","Cell RNA - HEL [nTPM]":"51.2","Cell RNA - HeLa [nTPM]":"147.4","Cell RNA - Hep G2 [nTPM]":"87.9","Cell RNA - HHSteC [nTPM]":"121.6","Cell RNA - HL-60 [nTPM]":"123.0","Cell RNA - HMC-1 [nTPM]":"147.8","Cell RNA - HSkMC [nTPM]":"115.2","Cell RNA - hTCEpi [nTPM]":"97.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"136.7","Cell RNA - hTERT-HME1 [nTPM]":"56.7","Cell RNA - hTERT-RPE1 [nTPM]":"49.7","Cell RNA - HUVEC TERT2 [nTPM]":"138.8","Cell RNA - JURKAT [nTPM]":"33.3","Cell RNA - K-562 [nTPM]":"105.5","Cell RNA - Karpas-707 [nTPM]":"25.8","Cell RNA - LHCN-M2 [nTPM]":"45.1","Cell RNA - MCF7 [nTPM]":"45.6","Cell RNA - MOLT-4 [nTPM]":"61.9","Cell RNA - NB-4 [nTPM]":"81.1","Cell RNA - NTERA-2 [nTPM]":"43.0","Cell RNA - OE19 [nTPM]":"75.8","Cell RNA - PC-3 [nTPM]":"115.3","Cell RNA - REH [nTPM]":"65.2","Cell RNA - RH-30 [nTPM]":"73.8","Cell RNA - RPMI-8226 [nTPM]":"80.9","Cell RNA - RPTEC TERT1 [nTPM]":"26.4","Cell RNA - RT4 [nTPM]":"67.2","Cell RNA - SCLC-21H [nTPM]":"41.2","Cell RNA - SH-SY5Y [nTPM]":"29.9","Cell RNA - SiHa [nTPM]":"102.8","Cell RNA - SK-BR-3 [nTPM]":"80.6","Cell RNA - SK-MEL-30 [nTPM]":"97.0","Cell RNA - SuSa [nTPM]":"36.7","Cell RNA - T-47d [nTPM]":"41.9","Cell RNA - THP-1 [nTPM]":"177.7","Cell RNA - TIME [nTPM]":"98.7","Cell RNA - U-138 MG [nTPM]":"240.8","Cell RNA - U-2 OS [nTPM]":"67.7","Cell RNA - U-2197 [nTPM]":"215.3","Cell RNA - U-251 MG [nTPM]":"156.2","Cell RNA - U-266\/70 [nTPM]":"45.4","Cell RNA - U-266\/84 [nTPM]":"125.1","Cell RNA - U-698 [nTPM]":"58.3","Cell RNA - U-87 MG [nTPM]":"142.7","Cell RNA - U-937 [nTPM]":"232.4","Cell RNA - WM-115 [nTPM]":"113.0","Blood RNA - basophil [nTPM]":"1.7","Blood RNA - classical monocyte [nTPM]":"25.7","Blood RNA - eosinophil [nTPM]":"12.5","Blood RNA - gdT-cell [nTPM]":"5.2","Blood RNA - intermediate monocyte [nTPM]":"28.1","Blood RNA - MAIT T-cell [nTPM]":"2.8","Blood RNA - memory B-cell [nTPM]":"3.5","Blood RNA - memory CD4 T-cell [nTPM]":"4.8","Blood RNA - memory CD8 T-cell [nTPM]":"4.9","Blood RNA - myeloid DC [nTPM]":"18.1","Blood RNA - naive B-cell [nTPM]":"3.3","Blood RNA - naive CD4 T-cell [nTPM]":"3.4","Blood RNA - naive CD8 T-cell [nTPM]":"5.3","Blood RNA - neutrophil [nTPM]":"3.6","Blood RNA - NK-cell [nTPM]":"2.1","Blood RNA - non-classical monocyte [nTPM]":"20.8","Blood RNA - plasmacytoid DC [nTPM]":"7.0","Blood RNA - T-reg [nTPM]":"3.1","Blood RNA - total PBMC [nTPM]":"14.5","Brain RNA - amygdala [nTPM]":"5.9","Brain RNA - basal ganglia [nTPM]":"6.9","Brain RNA - cerebellum [nTPM]":"7.9","Brain RNA - cerebral cortex [nTPM]":"8.4","Brain RNA - hippocampal formation [nTPM]":"7.1","Brain RNA - hypothalamus [nTPM]":"9.1","Brain RNA - medulla oblongata [nTPM]":"12.1","Brain RNA - midbrain [nTPM]":"9.3","Brain RNA - pons [nTPM]":"12.3","Brain RNA - spinal cord [nTPM]":"7.6","Brain RNA - thalamus [nTPM]":"18.9","Brain RNA - white matter [nTPM]":"12.6","Single Cell Type RNA - Adipocytes [nTPM]":"35.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.5","Single Cell Type RNA - Astrocytes [nTPM]":"11.1","Single Cell Type RNA - B-cells [nTPM]":"10.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"19.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"3.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"15.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.9","Single Cell Type RNA - dendritic cells [nTPM]":"28.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"13.1","Single Cell Type RNA - Early spermatids [nTPM]":"3.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"28.5","Single Cell Type RNA - Endothelial cells [nTPM]":"29.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"10.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"76.2","Single Cell Type RNA - Fibroblasts [nTPM]":"30.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.6","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"20.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"14.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"91.0","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.1","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"70.7","Single Cell Type RNA - Langerhans cells [nTPM]":"24.1","Single Cell Type RNA - Late spermatids [nTPM]":"3.1","Single Cell Type RNA - Leydig cells [nTPM]":"19.0","Single Cell Type RNA - Macrophages [nTPM]":"59.6","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"26.6","Single Cell Type RNA - Muller glia cells [nTPM]":"2.3","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.4","Single Cell Type RNA - Paneth cells [nTPM]":"7.6","Single Cell Type RNA - Peritubular cells [nTPM]":"21.8","Single Cell Type RNA - Plasma cells [nTPM]":"6.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"24.3","Single Cell Type RNA - Spermatocytes [nTPM]":"2.5","Single Cell Type RNA - Spermatogonia [nTPM]":"13.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.3","Single Cell Type RNA - T-cells [nTPM]":"12.0","Single Cell Type RNA - Theca cells [nTPM]":"24.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.2","Single Cell Type RNA - Urothelial cells [nTPM]":"8.4"},{"Gene":"COQ2","Gene synonym":["CL640","FLJ26072"],"Ensembl":"ENSG00000173085","Gene description":"Coenzyme Q2, polyprenyltransferase","Uniprot":["Q96H96"],"Chromosome":"4","Position":"83261536-83284914","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Isoprene biosynthesis","Ubiquinone biosynthesis"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Neurodegeneration","Parkinsonism","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"tongue":"37.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"50.7","Kupffer cells":"53.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056599","HPA068727"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA056599":"AB_2683184","HPA068727":"AB_2686022"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.0","Tissue RNA - adrenal gland [nTPM]":"17.0","Tissue RNA - amygdala [nTPM]":"2.8","Tissue RNA - appendix [nTPM]":"8.0","Tissue RNA - basal ganglia [nTPM]":"3.2","Tissue RNA - bone marrow [nTPM]":"11.8","Tissue RNA - breast [nTPM]":"5.8","Tissue RNA - cerebellum [nTPM]":"3.5","Tissue RNA - cerebral cortex [nTPM]":"3.3","Tissue RNA - cervix [nTPM]":"7.9","Tissue RNA - choroid plexus [nTPM]":"3.6","Tissue RNA - colon [nTPM]":"14.2","Tissue RNA - duodenum [nTPM]":"9.5","Tissue RNA - endometrium 1 [nTPM]":"6.3","Tissue RNA - epididymis [nTPM]":"7.5","Tissue RNA - esophagus [nTPM]":"10.4","Tissue RNA - fallopian tube [nTPM]":"4.4","Tissue RNA - gallbladder [nTPM]":"4.3","Tissue RNA - heart muscle [nTPM]":"15.0","Tissue RNA - hippocampal formation [nTPM]":"3.0","Tissue RNA - hypothalamus [nTPM]":"3.5","Tissue RNA - kidney [nTPM]":"5.6","Tissue RNA - liver [nTPM]":"13.6","Tissue RNA - lung [nTPM]":"7.9","Tissue RNA - lymph node [nTPM]":"6.4","Tissue RNA - medulla oblongata [nTPM]":"3.6","Tissue RNA - midbrain [nTPM]":"3.5","Tissue RNA - ovary [nTPM]":"6.5","Tissue RNA - pancreas [nTPM]":"6.5","Tissue RNA - parathyroid gland [nTPM]":"6.0","Tissue RNA - pituitary gland [nTPM]":"4.0","Tissue RNA - placenta [nTPM]":"8.4","Tissue RNA - pons [nTPM]":"3.8","Tissue RNA - prostate [nTPM]":"6.6","Tissue RNA - rectum [nTPM]":"14.2","Tissue RNA - retina [nTPM]":"4.0","Tissue RNA - salivary gland [nTPM]":"7.8","Tissue RNA - seminal vesicle [nTPM]":"5.0","Tissue RNA - skeletal muscle [nTPM]":"29.1","Tissue RNA - skin 1 [nTPM]":"10.8","Tissue RNA - small intestine [nTPM]":"9.1","Tissue RNA - smooth muscle [nTPM]":"6.9","Tissue RNA - spinal cord [nTPM]":"4.1","Tissue RNA - spleen [nTPM]":"10.1","Tissue RNA - stomach 1 [nTPM]":"5.5","Tissue RNA - testis [nTPM]":"3.5","Tissue RNA - thalamus [nTPM]":"3.9","Tissue RNA - thymus [nTPM]":"3.6","Tissue RNA - thyroid gland [nTPM]":"5.7","Tissue RNA - tongue [nTPM]":"37.5","Tissue RNA - tonsil [nTPM]":"7.1","Tissue RNA - urinary bladder [nTPM]":"7.9","Tissue RNA - vagina [nTPM]":"6.5","Tissue RNA - white matter [nTPM]":"4.9","Cell RNA - A-431 [nTPM]":"26.1","Cell RNA - A549 [nTPM]":"14.7","Cell RNA - AF22 [nTPM]":"14.1","Cell RNA - AN3-CA [nTPM]":"27.4","Cell RNA - ASC diff [nTPM]":"10.5","Cell RNA - ASC TERT1 [nTPM]":"11.9","Cell RNA - BEWO [nTPM]":"9.7","Cell RNA - BJ [nTPM]":"16.1","Cell RNA - BJ hTERT+ [nTPM]":"27.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"29.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"34.4","Cell RNA - CACO-2 [nTPM]":"10.5","Cell RNA - CAPAN-2 [nTPM]":"38.7","Cell RNA - Daudi [nTPM]":"17.2","Cell RNA - EFO-21 [nTPM]":"11.7","Cell RNA - fHDF\/TERT166 [nTPM]":"28.4","Cell RNA - GAMG [nTPM]":"24.6","Cell RNA - HaCaT [nTPM]":"18.6","Cell RNA - HAP1 [nTPM]":"23.9","Cell RNA - HBEC3-KT [nTPM]":"26.0","Cell RNA - HBF TERT88 [nTPM]":"38.7","Cell RNA - HDLM-2 [nTPM]":"17.2","Cell RNA - HEK 293 [nTPM]":"14.8","Cell RNA - HEL [nTPM]":"15.3","Cell RNA - HeLa [nTPM]":"22.3","Cell RNA - Hep G2 [nTPM]":"15.4","Cell RNA - HHSteC [nTPM]":"11.7","Cell RNA - HL-60 [nTPM]":"31.3","Cell RNA - HMC-1 [nTPM]":"73.5","Cell RNA - HSkMC [nTPM]":"15.9","Cell RNA - hTCEpi [nTPM]":"16.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.2","Cell RNA - hTERT-HME1 [nTPM]":"24.8","Cell RNA - hTERT-RPE1 [nTPM]":"8.9","Cell RNA - HUVEC TERT2 [nTPM]":"30.7","Cell RNA - JURKAT [nTPM]":"9.7","Cell RNA - K-562 [nTPM]":"10.0","Cell RNA - Karpas-707 [nTPM]":"21.4","Cell RNA - LHCN-M2 [nTPM]":"29.3","Cell RNA - MCF7 [nTPM]":"27.4","Cell RNA - MOLT-4 [nTPM]":"8.6","Cell RNA - NB-4 [nTPM]":"21.7","Cell RNA - NTERA-2 [nTPM]":"10.9","Cell RNA - OE19 [nTPM]":"30.6","Cell RNA - PC-3 [nTPM]":"19.9","Cell RNA - REH [nTPM]":"14.1","Cell RNA - RH-30 [nTPM]":"11.4","Cell RNA - RPMI-8226 [nTPM]":"22.1","Cell RNA - RPTEC TERT1 [nTPM]":"45.4","Cell RNA - RT4 [nTPM]":"13.8","Cell RNA - SCLC-21H [nTPM]":"10.3","Cell RNA - SH-SY5Y [nTPM]":"6.3","Cell RNA - SiHa [nTPM]":"19.0","Cell RNA - SK-BR-3 [nTPM]":"24.5","Cell RNA - SK-MEL-30 [nTPM]":"9.2","Cell RNA - SuSa [nTPM]":"6.7","Cell RNA - T-47d [nTPM]":"15.4","Cell RNA - THP-1 [nTPM]":"18.8","Cell RNA - TIME [nTPM]":"21.0","Cell RNA - U-138 MG [nTPM]":"14.6","Cell RNA - U-2 OS [nTPM]":"14.6","Cell RNA - U-2197 [nTPM]":"11.1","Cell RNA - U-251 MG [nTPM]":"23.4","Cell RNA - U-266\/70 [nTPM]":"5.7","Cell RNA - U-266\/84 [nTPM]":"5.2","Cell RNA - U-698 [nTPM]":"10.2","Cell RNA - U-87 MG [nTPM]":"29.5","Cell RNA - U-937 [nTPM]":"36.8","Cell RNA - WM-115 [nTPM]":"20.2","Blood RNA - basophil [nTPM]":"2.1","Blood RNA - classical monocyte [nTPM]":"28.8","Blood RNA - eosinophil [nTPM]":"4.0","Blood RNA - gdT-cell [nTPM]":"2.7","Blood RNA - intermediate monocyte [nTPM]":"26.8","Blood RNA - MAIT T-cell [nTPM]":"1.9","Blood RNA - memory B-cell [nTPM]":"6.2","Blood RNA - memory CD4 T-cell [nTPM]":"3.0","Blood RNA - memory CD8 T-cell [nTPM]":"2.5","Blood RNA - myeloid DC [nTPM]":"21.1","Blood RNA - naive B-cell [nTPM]":"6.9","Blood RNA - naive CD4 T-cell [nTPM]":"2.1","Blood RNA - naive CD8 T-cell [nTPM]":"3.2","Blood RNA - neutrophil [nTPM]":"9.8","Blood RNA - NK-cell [nTPM]":"6.7","Blood RNA - non-classical monocyte [nTPM]":"33.5","Blood RNA - plasmacytoid DC [nTPM]":"11.2","Blood RNA - T-reg [nTPM]":"4.1","Blood RNA - total PBMC [nTPM]":"13.6","Brain RNA - amygdala [nTPM]":"2.8","Brain RNA - basal ganglia [nTPM]":"3.2","Brain RNA - cerebellum [nTPM]":"3.5","Brain RNA - cerebral cortex [nTPM]":"3.3","Brain RNA - hippocampal formation [nTPM]":"3.0","Brain RNA - hypothalamus [nTPM]":"3.5","Brain RNA - medulla oblongata [nTPM]":"3.6","Brain RNA - midbrain [nTPM]":"3.5","Brain RNA - pons [nTPM]":"3.8","Brain RNA - spinal cord [nTPM]":"4.1","Brain RNA - thalamus [nTPM]":"3.9","Brain RNA - white matter [nTPM]":"4.9","Single Cell Type RNA - Adipocytes [nTPM]":"5.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.2","Single Cell Type RNA - Astrocytes [nTPM]":"15.7","Single Cell Type RNA - B-cells [nTPM]":"11.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"5.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"10.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.4","Single Cell Type RNA - dendritic cells [nTPM]":"7.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"31.3","Single Cell Type RNA - Ductal cells [nTPM]":"6.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.5","Single Cell Type RNA - Endothelial cells [nTPM]":"6.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"14.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"30.0","Single Cell Type RNA - Fibroblasts [nTPM]":"9.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"17.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.3","Single Cell Type RNA - Hepatocytes [nTPM]":"15.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"50.7","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.3","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"53.2","Single Cell Type RNA - Langerhans cells [nTPM]":"7.9","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"25.2","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"33.7","Single Cell Type RNA - monocytes [nTPM]":"21.8","Single Cell Type RNA - Muller glia cells [nTPM]":"12.6","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"25.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.4","Single Cell Type RNA - Paneth cells [nTPM]":"15.4","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"4.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.7","Single Cell Type RNA - Spermatocytes [nTPM]":"18.1","Single Cell Type RNA - Spermatogonia [nTPM]":"19.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.4","Single Cell Type RNA - T-cells [nTPM]":"9.6","Single Cell Type RNA - Theca cells [nTPM]":"35.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.7","Single Cell Type RNA - Urothelial cells [nTPM]":"12.9"},{"Gene":"COQ7","Gene synonym":["CAT5","CLK-1"],"Ensembl":"ENSG00000167186","Gene description":"Coenzyme Q7, hydroxylase","Uniprot":["Q99807"],"Chromosome":"16","Position":"19067614-19080095","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubiquinone biosynthesis"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"40.4","neutrophil":"126.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"126.5"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067252","HPA071922"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA067252":"AB_2685813","HPA071922":"AB_2686473"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.23e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.2","Tissue RNA - adrenal gland [nTPM]":"13.6","Tissue RNA - amygdala [nTPM]":"10.7","Tissue RNA - appendix [nTPM]":"7.0","Tissue RNA - basal ganglia [nTPM]":"11.2","Tissue RNA - bone marrow [nTPM]":"4.8","Tissue RNA - breast [nTPM]":"13.4","Tissue RNA - cerebellum [nTPM]":"10.9","Tissue RNA - cerebral cortex [nTPM]":"11.6","Tissue RNA - cervix [nTPM]":"10.8","Tissue RNA - choroid plexus [nTPM]":"12.5","Tissue RNA - colon [nTPM]":"14.1","Tissue RNA - duodenum [nTPM]":"12.4","Tissue RNA - endometrium 1 [nTPM]":"15.6","Tissue RNA - epididymis [nTPM]":"12.3","Tissue RNA - esophagus [nTPM]":"12.4","Tissue RNA - fallopian tube [nTPM]":"15.5","Tissue RNA - gallbladder [nTPM]":"10.7","Tissue RNA - heart muscle [nTPM]":"23.4","Tissue RNA - hippocampal formation [nTPM]":"11.0","Tissue RNA - hypothalamus [nTPM]":"10.8","Tissue RNA - kidney [nTPM]":"14.1","Tissue RNA - liver [nTPM]":"12.3","Tissue RNA - lung [nTPM]":"10.0","Tissue RNA - lymph node [nTPM]":"8.3","Tissue RNA - medulla oblongata [nTPM]":"10.6","Tissue RNA - midbrain [nTPM]":"11.3","Tissue RNA - ovary [nTPM]":"20.0","Tissue RNA - pancreas [nTPM]":"10.3","Tissue RNA - parathyroid gland [nTPM]":"24.4","Tissue RNA - pituitary gland [nTPM]":"9.7","Tissue RNA - placenta [nTPM]":"10.0","Tissue RNA - pons [nTPM]":"11.1","Tissue RNA - prostate [nTPM]":"17.7","Tissue RNA - rectum [nTPM]":"13.2","Tissue RNA - retina [nTPM]":"14.0","Tissue RNA - salivary gland [nTPM]":"10.4","Tissue RNA - seminal vesicle [nTPM]":"14.7","Tissue RNA - skeletal muscle [nTPM]":"45.8","Tissue RNA - skin 1 [nTPM]":"7.9","Tissue RNA - small intestine [nTPM]":"11.8","Tissue RNA - smooth muscle [nTPM]":"11.6","Tissue RNA - spinal cord [nTPM]":"10.4","Tissue RNA - spleen [nTPM]":"10.0","Tissue RNA - stomach 1 [nTPM]":"12.8","Tissue RNA - testis [nTPM]":"20.9","Tissue RNA - thalamus [nTPM]":"11.3","Tissue RNA - thymus [nTPM]":"10.3","Tissue RNA - thyroid gland [nTPM]":"16.2","Tissue RNA - tongue [nTPM]":"44.9","Tissue RNA - tonsil [nTPM]":"8.4","Tissue RNA - urinary bladder [nTPM]":"10.3","Tissue RNA - vagina [nTPM]":"8.8","Tissue RNA - white matter [nTPM]":"13.1","Cell RNA - A-431 [nTPM]":"23.5","Cell RNA - A549 [nTPM]":"24.8","Cell RNA - AF22 [nTPM]":"21.1","Cell RNA - AN3-CA [nTPM]":"12.4","Cell RNA - ASC diff [nTPM]":"11.6","Cell RNA - ASC TERT1 [nTPM]":"12.2","Cell RNA - BEWO [nTPM]":"17.7","Cell RNA - BJ [nTPM]":"13.5","Cell RNA - BJ hTERT+ [nTPM]":"11.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"18.5","Cell RNA - CACO-2 [nTPM]":"15.9","Cell RNA - CAPAN-2 [nTPM]":"19.1","Cell RNA - Daudi [nTPM]":"17.8","Cell RNA - EFO-21 [nTPM]":"63.9","Cell RNA - fHDF\/TERT166 [nTPM]":"10.4","Cell RNA - GAMG [nTPM]":"19.4","Cell RNA - HaCaT [nTPM]":"24.5","Cell RNA - HAP1 [nTPM]":"29.6","Cell RNA - HBEC3-KT [nTPM]":"16.9","Cell RNA - HBF TERT88 [nTPM]":"13.0","Cell RNA - HDLM-2 [nTPM]":"15.2","Cell RNA - HEK 293 [nTPM]":"29.9","Cell RNA - HEL [nTPM]":"9.5","Cell RNA - HeLa [nTPM]":"22.8","Cell RNA - Hep G2 [nTPM]":"49.3","Cell RNA - HHSteC [nTPM]":"14.4","Cell RNA - HL-60 [nTPM]":"22.9","Cell RNA - HMC-1 [nTPM]":"20.1","Cell RNA - HSkMC [nTPM]":"10.3","Cell RNA - hTCEpi [nTPM]":"14.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.8","Cell RNA - hTERT-HME1 [nTPM]":"12.2","Cell RNA - hTERT-RPE1 [nTPM]":"14.8","Cell RNA - HUVEC TERT2 [nTPM]":"14.8","Cell RNA - JURKAT [nTPM]":"20.9","Cell RNA - K-562 [nTPM]":"26.4","Cell RNA - Karpas-707 [nTPM]":"16.2","Cell RNA - LHCN-M2 [nTPM]":"12.9","Cell RNA - MCF7 [nTPM]":"42.4","Cell RNA - MOLT-4 [nTPM]":"24.0","Cell RNA - NB-4 [nTPM]":"18.4","Cell RNA - NTERA-2 [nTPM]":"16.1","Cell RNA - OE19 [nTPM]":"9.1","Cell RNA - PC-3 [nTPM]":"13.1","Cell RNA - REH [nTPM]":"29.0","Cell RNA - RH-30 [nTPM]":"23.3","Cell RNA - RPMI-8226 [nTPM]":"22.8","Cell RNA - RPTEC TERT1 [nTPM]":"15.7","Cell RNA - RT4 [nTPM]":"15.5","Cell RNA - SCLC-21H [nTPM]":"30.4","Cell RNA - SH-SY5Y [nTPM]":"17.4","Cell RNA - SiHa [nTPM]":"12.6","Cell RNA - SK-BR-3 [nTPM]":"27.4","Cell RNA - SK-MEL-30 [nTPM]":"16.2","Cell RNA - SuSa [nTPM]":"10.2","Cell RNA - T-47d [nTPM]":"25.2","Cell RNA - THP-1 [nTPM]":"30.7","Cell RNA - TIME [nTPM]":"16.3","Cell RNA - U-138 MG [nTPM]":"19.0","Cell RNA - U-2 OS [nTPM]":"10.9","Cell RNA - U-2197 [nTPM]":"14.1","Cell RNA - U-251 MG [nTPM]":"19.7","Cell RNA - U-266\/70 [nTPM]":"15.0","Cell RNA - U-266\/84 [nTPM]":"26.2","Cell RNA - U-698 [nTPM]":"19.7","Cell RNA - U-87 MG [nTPM]":"20.4","Cell RNA - U-937 [nTPM]":"13.1","Cell RNA - WM-115 [nTPM]":"12.5","Blood RNA - basophil [nTPM]":"40.4","Blood RNA - classical monocyte [nTPM]":"11.4","Blood RNA - eosinophil [nTPM]":"17.8","Blood RNA - gdT-cell [nTPM]":"9.9","Blood RNA - intermediate monocyte [nTPM]":"10.6","Blood RNA - MAIT T-cell [nTPM]":"9.4","Blood RNA - memory B-cell [nTPM]":"16.3","Blood RNA - memory CD4 T-cell [nTPM]":"8.9","Blood RNA - memory CD8 T-cell [nTPM]":"8.7","Blood RNA - myeloid DC [nTPM]":"12.6","Blood RNA - naive B-cell [nTPM]":"15.3","Blood RNA - naive CD4 T-cell [nTPM]":"12.2","Blood RNA - naive CD8 T-cell [nTPM]":"10.8","Blood RNA - neutrophil [nTPM]":"126.5","Blood RNA - NK-cell [nTPM]":"12.9","Blood RNA - non-classical monocyte [nTPM]":"12.3","Blood RNA - plasmacytoid DC [nTPM]":"15.6","Blood RNA - T-reg [nTPM]":"6.2","Blood RNA - total PBMC [nTPM]":"5.6","Brain RNA - amygdala [nTPM]":"10.7","Brain RNA - basal ganglia [nTPM]":"11.2","Brain RNA - cerebellum [nTPM]":"10.9","Brain RNA - cerebral cortex [nTPM]":"11.6","Brain RNA - hippocampal formation [nTPM]":"11.0","Brain RNA - hypothalamus [nTPM]":"10.8","Brain RNA - medulla oblongata [nTPM]":"10.6","Brain RNA - midbrain [nTPM]":"11.3","Brain RNA - pons [nTPM]":"11.1","Brain RNA - spinal cord [nTPM]":"10.4","Brain RNA - thalamus [nTPM]":"11.3","Brain RNA - white matter [nTPM]":"13.1","Single Cell Type RNA - Adipocytes [nTPM]":"13.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.6","Single Cell Type RNA - Astrocytes [nTPM]":"6.2","Single Cell Type RNA - B-cells [nTPM]":"35.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"26.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"20.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"31.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"21.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"31.5","Single Cell Type RNA - Club cells [nTPM]":"14.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"21.2","Single Cell Type RNA - dendritic cells [nTPM]":"28.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"38.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"45.0","Single Cell Type RNA - Ductal cells [nTPM]":"25.2","Single Cell Type RNA - Early spermatids [nTPM]":"14.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.2","Single Cell Type RNA - Endothelial cells [nTPM]":"16.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"24.0","Single Cell Type RNA - Erythroid cells [nTPM]":"4.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.9","Single Cell Type RNA - Fibroblasts [nTPM]":"14.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"23.2","Single Cell Type RNA - granulocytes [nTPM]":"25.4","Single Cell Type RNA - Granulosa cells [nTPM]":"31.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.7","Single Cell Type RNA - Hepatocytes [nTPM]":"11.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.3","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"39.0","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"29.4","Single Cell Type RNA - Langerhans cells [nTPM]":"12.9","Single Cell Type RNA - Late spermatids [nTPM]":"8.5","Single Cell Type RNA - Leydig cells [nTPM]":"18.6","Single Cell Type RNA - Macrophages [nTPM]":"18.8","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"11.6","Single Cell Type RNA - Muller glia cells [nTPM]":"39.5","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.2","Single Cell Type RNA - Paneth cells [nTPM]":"30.4","Single Cell Type RNA - Peritubular cells [nTPM]":"13.9","Single Cell Type RNA - Plasma cells [nTPM]":"11.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"71.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"24.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"53.9","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.2","Single Cell Type RNA - Spermatocytes [nTPM]":"81.3","Single Cell Type RNA - Spermatogonia [nTPM]":"53.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"32.2","Single Cell Type RNA - T-cells [nTPM]":"23.9","Single Cell Type RNA - Theca cells [nTPM]":"38.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"39.8","Single Cell Type RNA - Urothelial cells [nTPM]":"24.0"},{"Gene":"COQ8A","Gene synonym":["ADCK3","CABC1","COQ8","SCAR9"],"Ensembl":"ENSG00000163050","Gene description":"Coenzyme Q8A","Uniprot":["Q8NI60"],"Chromosome":"1","Position":"226940286-226987544","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubiquinone biosynthesis"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant","Neurodegeneration","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"skeletal muscle":"1165.1","tongue":"484.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"21.9","Collecting duct cells":"33.1","Ductal cells":"21.2","Exocrine glandular cells":"32.7","Proximal tubular cells":"24.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEK 293":"82.0","RPMI-8226":"78.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA061662"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA061662":"AB_2684578"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Tissue RNA - adipose tissue [nTPM]":"63.9","Tissue RNA - adrenal gland [nTPM]":"123.8","Tissue RNA - amygdala [nTPM]":"7.1","Tissue RNA - appendix [nTPM]":"10.3","Tissue RNA - basal ganglia [nTPM]":"8.0","Tissue RNA - bone marrow [nTPM]":"26.1","Tissue RNA - breast [nTPM]":"35.8","Tissue RNA - cerebellum [nTPM]":"17.3","Tissue RNA - cerebral cortex [nTPM]":"8.1","Tissue RNA - cervix [nTPM]":"16.5","Tissue RNA - choroid plexus [nTPM]":"16.1","Tissue RNA - colon [nTPM]":"30.8","Tissue RNA - duodenum [nTPM]":"29.9","Tissue RNA - endometrium 1 [nTPM]":"15.9","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"32.2","Tissue RNA - fallopian tube [nTPM]":"24.6","Tissue RNA - gallbladder [nTPM]":"19.7","Tissue RNA - heart muscle [nTPM]":"123.5","Tissue RNA - hippocampal formation [nTPM]":"7.1","Tissue RNA - hypothalamus [nTPM]":"5.6","Tissue RNA - kidney [nTPM]":"14.4","Tissue RNA - liver [nTPM]":"35.7","Tissue RNA - lung [nTPM]":"9.6","Tissue RNA - lymph node [nTPM]":"12.7","Tissue RNA - medulla oblongata [nTPM]":"8.9","Tissue RNA - midbrain [nTPM]":"5.4","Tissue RNA - ovary [nTPM]":"34.1","Tissue RNA - pancreas [nTPM]":"93.8","Tissue RNA - parathyroid gland [nTPM]":"6.4","Tissue RNA - pituitary gland [nTPM]":"5.3","Tissue RNA - placenta [nTPM]":"6.5","Tissue RNA - pons [nTPM]":"9.8","Tissue RNA - prostate [nTPM]":"18.5","Tissue RNA - rectum [nTPM]":"6.4","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"32.7","Tissue RNA - seminal vesicle [nTPM]":"11.7","Tissue RNA - skeletal muscle [nTPM]":"1165.1","Tissue RNA - skin 1 [nTPM]":"25.1","Tissue RNA - small intestine [nTPM]":"18.5","Tissue RNA - smooth muscle [nTPM]":"7.2","Tissue RNA - spinal cord [nTPM]":"5.9","Tissue RNA - spleen [nTPM]":"14.4","Tissue RNA - stomach 1 [nTPM]":"52.8","Tissue RNA - testis [nTPM]":"6.7","Tissue RNA - thalamus [nTPM]":"5.9","Tissue RNA - thymus [nTPM]":"8.6","Tissue RNA - thyroid gland [nTPM]":"9.4","Tissue RNA - tongue [nTPM]":"484.7","Tissue RNA - tonsil [nTPM]":"4.3","Tissue RNA - urinary bladder [nTPM]":"40.8","Tissue RNA - vagina [nTPM]":"13.4","Tissue RNA - white matter [nTPM]":"11.5","Cell RNA - A-431 [nTPM]":"8.0","Cell RNA - A549 [nTPM]":"14.4","Cell RNA - AF22 [nTPM]":"3.3","Cell RNA - AN3-CA [nTPM]":"10.3","Cell RNA - ASC diff [nTPM]":"11.4","Cell RNA - ASC TERT1 [nTPM]":"7.3","Cell RNA - BEWO [nTPM]":"57.7","Cell RNA - BJ [nTPM]":"3.6","Cell RNA - BJ hTERT+ [nTPM]":"2.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.9","Cell RNA - CACO-2 [nTPM]":"23.0","Cell RNA - CAPAN-2 [nTPM]":"12.8","Cell RNA - Daudi [nTPM]":"24.5","Cell RNA - EFO-21 [nTPM]":"17.9","Cell RNA - fHDF\/TERT166 [nTPM]":"2.4","Cell RNA - GAMG [nTPM]":"2.6","Cell RNA - HaCaT [nTPM]":"9.2","Cell RNA - HAP1 [nTPM]":"6.9","Cell RNA - HBEC3-KT [nTPM]":"8.2","Cell RNA - HBF TERT88 [nTPM]":"0.8","Cell RNA - HDLM-2 [nTPM]":"25.5","Cell RNA - HEK 293 [nTPM]":"82.0","Cell RNA - HEL [nTPM]":"16.7","Cell RNA - HeLa [nTPM]":"11.2","Cell RNA - Hep G2 [nTPM]":"38.8","Cell RNA - HHSteC [nTPM]":"2.5","Cell RNA - HL-60 [nTPM]":"25.8","Cell RNA - HMC-1 [nTPM]":"9.3","Cell RNA - HSkMC [nTPM]":"14.2","Cell RNA - hTCEpi [nTPM]":"12.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.0","Cell RNA - hTERT-HME1 [nTPM]":"5.4","Cell RNA - hTERT-RPE1 [nTPM]":"4.9","Cell RNA - HUVEC TERT2 [nTPM]":"2.5","Cell RNA - JURKAT [nTPM]":"24.7","Cell RNA - K-562 [nTPM]":"29.4","Cell RNA - Karpas-707 [nTPM]":"19.4","Cell RNA - LHCN-M2 [nTPM]":"0.7","Cell RNA - MCF7 [nTPM]":"11.0","Cell RNA - MOLT-4 [nTPM]":"15.2","Cell RNA - NB-4 [nTPM]":"37.3","Cell RNA - NTERA-2 [nTPM]":"15.5","Cell RNA - OE19 [nTPM]":"62.8","Cell RNA - PC-3 [nTPM]":"29.5","Cell RNA - REH [nTPM]":"14.9","Cell RNA - RH-30 [nTPM]":"17.1","Cell RNA - RPMI-8226 [nTPM]":"78.6","Cell RNA - RPTEC TERT1 [nTPM]":"1.6","Cell RNA - RT4 [nTPM]":"5.9","Cell RNA - SCLC-21H [nTPM]":"59.9","Cell RNA - SH-SY5Y [nTPM]":"24.2","Cell RNA - SiHa [nTPM]":"7.3","Cell RNA - SK-BR-3 [nTPM]":"28.7","Cell RNA - SK-MEL-30 [nTPM]":"20.6","Cell RNA - SuSa [nTPM]":"3.4","Cell RNA - T-47d [nTPM]":"15.1","Cell RNA - THP-1 [nTPM]":"34.8","Cell RNA - TIME [nTPM]":"2.5","Cell RNA - U-138 MG [nTPM]":"5.9","Cell RNA - U-2 OS [nTPM]":"5.3","Cell RNA - U-2197 [nTPM]":"8.2","Cell RNA - U-251 MG [nTPM]":"13.3","Cell RNA - U-266\/70 [nTPM]":"43.0","Cell RNA - U-266\/84 [nTPM]":"40.5","Cell RNA - U-698 [nTPM]":"13.1","Cell RNA - U-87 MG [nTPM]":"5.3","Cell RNA - U-937 [nTPM]":"29.3","Cell RNA - WM-115 [nTPM]":"6.0","Blood RNA - basophil [nTPM]":"47.7","Blood RNA - classical monocyte [nTPM]":"23.5","Blood RNA - eosinophil [nTPM]":"68.4","Blood RNA - gdT-cell [nTPM]":"15.8","Blood RNA - intermediate monocyte [nTPM]":"17.1","Blood RNA - MAIT T-cell [nTPM]":"15.3","Blood RNA - memory B-cell [nTPM]":"22.2","Blood RNA - memory CD4 T-cell [nTPM]":"15.8","Blood RNA - memory CD8 T-cell [nTPM]":"14.6","Blood RNA - myeloid DC [nTPM]":"18.6","Blood RNA - naive B-cell [nTPM]":"26.8","Blood RNA - naive CD4 T-cell [nTPM]":"21.5","Blood RNA - naive CD8 T-cell [nTPM]":"17.0","Blood RNA - neutrophil [nTPM]":"43.1","Blood RNA - NK-cell [nTPM]":"21.2","Blood RNA - non-classical monocyte [nTPM]":"13.6","Blood RNA - plasmacytoid DC [nTPM]":"8.1","Blood RNA - T-reg [nTPM]":"21.5","Blood RNA - total PBMC [nTPM]":"26.0","Brain RNA - amygdala [nTPM]":"7.1","Brain RNA - basal ganglia [nTPM]":"8.0","Brain RNA - cerebellum [nTPM]":"17.3","Brain RNA - cerebral cortex [nTPM]":"8.1","Brain RNA - hippocampal formation [nTPM]":"7.1","Brain RNA - hypothalamus [nTPM]":"5.6","Brain RNA - medulla oblongata [nTPM]":"8.9","Brain RNA - midbrain [nTPM]":"5.4","Brain RNA - pons [nTPM]":"9.8","Brain RNA - spinal cord [nTPM]":"5.9","Brain RNA - thalamus [nTPM]":"5.9","Brain RNA - white matter [nTPM]":"11.5","Single Cell Type RNA - Adipocytes [nTPM]":"11.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"5.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"4.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.2","Single Cell Type RNA - dendritic cells [nTPM]":"10.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"21.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.9","Single Cell Type RNA - Endothelial cells [nTPM]":"5.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"32.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.0","Single Cell Type RNA - Fibroblasts [nTPM]":"6.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.6","Single Cell Type RNA - granulocytes [nTPM]":"13.9","Single Cell Type RNA - Granulosa cells [nTPM]":"9.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"6.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"11.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"3.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"24.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.7","Single Cell Type RNA - T-cells [nTPM]":"5.2","Single Cell Type RNA - Theca cells [nTPM]":"16.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"COQ8B","Gene synonym":["ADCK4","COQ8","FLJ12229"],"Ensembl":"ENSG00000123815","Gene description":"Coenzyme Q8B","Uniprot":["Q96D53"],"Chromosome":"19","Position":"40691514-40725784","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"16.5","Endometrial ciliated cells":"16.4","Theca cells":"19.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027229","HPA027277","HPA027279","HPA028303"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA027229":"AB_10600100","HPA027277":"AB_10599857","HPA027279":"AB_10601219","HPA028303":"AB_2672551"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.1","Tissue RNA - adrenal gland [nTPM]":"25.2","Tissue RNA - amygdala [nTPM]":"10.1","Tissue RNA - appendix [nTPM]":"5.7","Tissue RNA - basal ganglia [nTPM]":"10.7","Tissue RNA - bone marrow [nTPM]":"5.9","Tissue RNA - breast [nTPM]":"15.3","Tissue RNA - cerebellum [nTPM]":"10.4","Tissue RNA - cerebral cortex [nTPM]":"12.8","Tissue RNA - cervix [nTPM]":"23.4","Tissue RNA - choroid plexus [nTPM]":"10.9","Tissue RNA - colon [nTPM]":"19.4","Tissue RNA - duodenum [nTPM]":"9.7","Tissue RNA - endometrium 1 [nTPM]":"22.0","Tissue RNA - epididymis [nTPM]":"2.3","Tissue RNA - esophagus [nTPM]":"16.0","Tissue RNA - fallopian tube [nTPM]":"29.8","Tissue RNA - gallbladder [nTPM]":"7.6","Tissue RNA - heart muscle [nTPM]":"21.9","Tissue RNA - hippocampal formation [nTPM]":"9.8","Tissue RNA - hypothalamus [nTPM]":"10.6","Tissue RNA - kidney [nTPM]":"21.0","Tissue RNA - liver [nTPM]":"25.7","Tissue RNA - lung [nTPM]":"16.4","Tissue RNA - lymph node [nTPM]":"6.0","Tissue RNA - medulla oblongata [nTPM]":"10.6","Tissue RNA - midbrain [nTPM]":"10.8","Tissue RNA - ovary [nTPM]":"22.5","Tissue RNA - pancreas [nTPM]":"20.7","Tissue RNA - parathyroid gland [nTPM]":"8.4","Tissue RNA - pituitary gland [nTPM]":"49.3","Tissue RNA - placenta [nTPM]":"3.5","Tissue RNA - pons [nTPM]":"10.3","Tissue RNA - prostate [nTPM]":"23.2","Tissue RNA - rectum [nTPM]":"2.3","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"16.9","Tissue RNA - seminal vesicle [nTPM]":"7.3","Tissue RNA - skeletal muscle [nTPM]":"14.4","Tissue RNA - skin 1 [nTPM]":"20.2","Tissue RNA - small intestine [nTPM]":"17.8","Tissue RNA - smooth muscle [nTPM]":"3.8","Tissue RNA - spinal cord [nTPM]":"11.2","Tissue RNA - spleen [nTPM]":"18.3","Tissue RNA - stomach 1 [nTPM]":"23.9","Tissue RNA - testis [nTPM]":"17.3","Tissue RNA - thalamus [nTPM]":"10.6","Tissue RNA - thymus [nTPM]":"8.8","Tissue RNA - thyroid gland [nTPM]":"23.3","Tissue RNA - tongue [nTPM]":"8.6","Tissue RNA - tonsil [nTPM]":"3.3","Tissue RNA - urinary bladder [nTPM]":"20.3","Tissue RNA - vagina [nTPM]":"18.4","Tissue RNA - white matter [nTPM]":"10.5","Cell RNA - A-431 [nTPM]":"9.9","Cell RNA - A549 [nTPM]":"39.5","Cell RNA - AF22 [nTPM]":"7.9","Cell RNA - AN3-CA [nTPM]":"18.5","Cell RNA - ASC diff [nTPM]":"7.8","Cell RNA - ASC TERT1 [nTPM]":"6.1","Cell RNA - BEWO [nTPM]":"8.5","Cell RNA - BJ [nTPM]":"6.6","Cell RNA - BJ hTERT+ [nTPM]":"7.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.1","Cell RNA - CACO-2 [nTPM]":"15.4","Cell RNA - CAPAN-2 [nTPM]":"14.3","Cell RNA - Daudi [nTPM]":"13.8","Cell RNA - EFO-21 [nTPM]":"20.0","Cell RNA - fHDF\/TERT166 [nTPM]":"4.3","Cell RNA - GAMG [nTPM]":"7.8","Cell RNA - HaCaT [nTPM]":"9.8","Cell RNA - HAP1 [nTPM]":"7.0","Cell RNA - HBEC3-KT [nTPM]":"10.5","Cell RNA - HBF TERT88 [nTPM]":"2.0","Cell RNA - HDLM-2 [nTPM]":"20.0","Cell RNA - HEK 293 [nTPM]":"10.4","Cell RNA - HEL [nTPM]":"11.6","Cell RNA - HeLa [nTPM]":"12.7","Cell RNA - Hep G2 [nTPM]":"6.4","Cell RNA - HHSteC [nTPM]":"12.1","Cell RNA - HL-60 [nTPM]":"4.1","Cell RNA - HMC-1 [nTPM]":"19.2","Cell RNA - HSkMC [nTPM]":"8.4","Cell RNA - hTCEpi [nTPM]":"10.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.4","Cell RNA - hTERT-HME1 [nTPM]":"5.4","Cell RNA - hTERT-RPE1 [nTPM]":"5.2","Cell RNA - HUVEC TERT2 [nTPM]":"7.4","Cell RNA - JURKAT [nTPM]":"13.7","Cell RNA - K-562 [nTPM]":"7.7","Cell RNA - Karpas-707 [nTPM]":"8.1","Cell RNA - LHCN-M2 [nTPM]":"6.0","Cell RNA - MCF7 [nTPM]":"6.4","Cell RNA - MOLT-4 [nTPM]":"4.9","Cell RNA - NB-4 [nTPM]":"5.7","Cell RNA - NTERA-2 [nTPM]":"6.4","Cell RNA - OE19 [nTPM]":"11.5","Cell RNA - PC-3 [nTPM]":"3.6","Cell RNA - REH [nTPM]":"11.5","Cell RNA - RH-30 [nTPM]":"13.1","Cell RNA - RPMI-8226 [nTPM]":"12.4","Cell RNA - RPTEC TERT1 [nTPM]":"15.7","Cell RNA - RT4 [nTPM]":"17.6","Cell RNA - SCLC-21H [nTPM]":"15.1","Cell RNA - SH-SY5Y [nTPM]":"11.0","Cell RNA - SiHa [nTPM]":"12.5","Cell RNA - SK-BR-3 [nTPM]":"20.4","Cell RNA - SK-MEL-30 [nTPM]":"21.0","Cell RNA - SuSa [nTPM]":"4.4","Cell RNA - T-47d [nTPM]":"22.8","Cell RNA - THP-1 [nTPM]":"17.1","Cell RNA - TIME [nTPM]":"9.4","Cell RNA - U-138 MG [nTPM]":"5.1","Cell RNA - U-2 OS [nTPM]":"20.6","Cell RNA - U-2197 [nTPM]":"3.9","Cell RNA - U-251 MG [nTPM]":"5.5","Cell RNA - U-266\/70 [nTPM]":"9.4","Cell RNA - U-266\/84 [nTPM]":"9.0","Cell RNA - U-698 [nTPM]":"7.3","Cell RNA - U-87 MG [nTPM]":"27.8","Cell RNA - U-937 [nTPM]":"5.2","Cell RNA - WM-115 [nTPM]":"9.1","Blood RNA - basophil [nTPM]":"10.2","Blood RNA - classical monocyte [nTPM]":"9.4","Blood RNA - eosinophil [nTPM]":"8.7","Blood RNA - gdT-cell [nTPM]":"6.7","Blood RNA - intermediate monocyte [nTPM]":"9.3","Blood RNA - MAIT T-cell [nTPM]":"8.3","Blood RNA - memory B-cell [nTPM]":"7.1","Blood RNA - memory CD4 T-cell [nTPM]":"5.5","Blood RNA - memory CD8 T-cell [nTPM]":"7.8","Blood RNA - myeloid DC [nTPM]":"9.9","Blood RNA - naive B-cell [nTPM]":"5.9","Blood RNA - naive CD4 T-cell [nTPM]":"4.6","Blood RNA - naive CD8 T-cell [nTPM]":"5.1","Blood RNA - neutrophil [nTPM]":"9.0","Blood RNA - NK-cell [nTPM]":"6.9","Blood RNA - non-classical monocyte [nTPM]":"9.2","Blood RNA - plasmacytoid DC [nTPM]":"4.6","Blood RNA - T-reg [nTPM]":"4.9","Blood RNA - total PBMC [nTPM]":"7.3","Brain RNA - amygdala [nTPM]":"10.1","Brain RNA - basal ganglia [nTPM]":"10.7","Brain RNA - cerebellum [nTPM]":"10.4","Brain RNA - cerebral cortex [nTPM]":"12.8","Brain RNA - hippocampal formation [nTPM]":"9.8","Brain RNA - hypothalamus [nTPM]":"10.6","Brain RNA - medulla oblongata [nTPM]":"10.6","Brain RNA - midbrain [nTPM]":"10.8","Brain RNA - pons [nTPM]":"10.3","Brain RNA - spinal cord [nTPM]":"11.2","Brain RNA - thalamus [nTPM]":"10.6","Brain RNA - white matter [nTPM]":"10.5","Single Cell Type RNA - Adipocytes [nTPM]":"8.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.1","Single Cell Type RNA - dendritic cells [nTPM]":"6.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"16.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.8","Single Cell Type RNA - Endothelial cells [nTPM]":"1.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.8","Single Cell Type RNA - Fibroblasts [nTPM]":"5.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.3","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"11.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"4.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"6.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.4","Single Cell Type RNA - T-cells [nTPM]":"3.2","Single Cell Type RNA - Theca cells [nTPM]":"19.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CORIN","Gene synonym":["ATC2","CRN","Lrp4","PRSC","TMPRSS10"],"Ensembl":"ENSG00000145244","Gene description":"Corin, serine peptidase","Uniprot":["Q9Y5Q5"],"Chromosome":"4","Position":"47593999-47838106","Protein class":["Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"heart muscle":"56.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Cardiomyocytes":"69.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"ASC TERT1":"44.0"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"2.6"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070941"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies","Plasma membrane","Actin filaments"],"Secretome location":"Intracellular and membrane","CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear bodies","Actin filaments"],"Antibody RRID":{"HPA070941":"AB_2686324"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.0","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"2.1","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"4.5","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"0.9","Tissue RNA - fallopian tube [nTPM]":"1.4","Tissue RNA - gallbladder [nTPM]":"4.5","Tissue RNA - heart muscle [nTPM]":"56.9","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"1.0","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"1.9","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.7","Tissue RNA - midbrain [nTPM]":"0.6","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"1.1","Tissue RNA - pituitary gland [nTPM]":"1.9","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"2.3","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"6.1","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"7.5","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.7","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"1.1","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"2.5","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"1.2","Tissue RNA - vagina [nTPM]":"3.9","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"10.3","Cell RNA - ASC TERT1 [nTPM]":"44.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"2.0","Cell RNA - BJ hTERT+ [nTPM]":"3.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"2.1","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"1.8","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.9","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.9","Cell RNA - U-2 OS [nTPM]":"1.4","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"1.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.7","Brain RNA - midbrain [nTPM]":"0.6","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.5","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"69.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"6.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.3","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"9.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"5.5","Single Cell Type RNA - Late spermatids [nTPM]":"2.0","Single Cell Type RNA - Leydig cells [nTPM]":"4.7","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.3","Single Cell Type RNA - Spermatocytes [nTPM]":"4.6","Single Cell Type RNA - Spermatogonia [nTPM]":"4.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"COX10","Gene synonym":[],"Ensembl":"ENSG00000006695","Gene description":"Cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10","Uniprot":["Q12887"],"Chromosome":"17","Position":"14069490-14231736","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Heme biosynthesis"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Leigh syndrome","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"44.5","tongue":"44.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"88.2","Late spermatids":"81.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032005","HPA032006"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoli","Cytosol"],"Antibody RRID":{"HPA032005":"AB_10603560","HPA032006":"AB_10670554"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.32e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.73e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.1","Tissue RNA - adrenal gland [nTPM]":"7.5","Tissue RNA - amygdala [nTPM]":"3.1","Tissue RNA - appendix [nTPM]":"5.4","Tissue RNA - basal ganglia [nTPM]":"2.9","Tissue RNA - bone marrow [nTPM]":"10.4","Tissue RNA - breast [nTPM]":"6.0","Tissue RNA - cerebellum [nTPM]":"4.1","Tissue RNA - cerebral cortex [nTPM]":"4.4","Tissue RNA - cervix [nTPM]":"5.8","Tissue RNA - choroid plexus [nTPM]":"4.3","Tissue RNA - colon [nTPM]":"12.5","Tissue RNA - duodenum [nTPM]":"12.5","Tissue RNA - endometrium 1 [nTPM]":"5.2","Tissue RNA - epididymis [nTPM]":"4.4","Tissue RNA - esophagus [nTPM]":"10.9","Tissue RNA - fallopian tube [nTPM]":"5.6","Tissue RNA - gallbladder [nTPM]":"4.2","Tissue RNA - heart muscle [nTPM]":"27.9","Tissue RNA - hippocampal formation [nTPM]":"3.3","Tissue RNA - hypothalamus [nTPM]":"3.9","Tissue RNA - kidney [nTPM]":"11.6","Tissue RNA - liver [nTPM]":"10.6","Tissue RNA - lung [nTPM]":"4.4","Tissue RNA - lymph node [nTPM]":"5.8","Tissue RNA - medulla oblongata [nTPM]":"3.8","Tissue RNA - midbrain [nTPM]":"3.5","Tissue RNA - ovary [nTPM]":"4.5","Tissue RNA - pancreas [nTPM]":"9.9","Tissue RNA - parathyroid gland [nTPM]":"9.6","Tissue RNA - pituitary gland [nTPM]":"3.3","Tissue RNA - placenta [nTPM]":"7.0","Tissue RNA - pons [nTPM]":"3.5","Tissue RNA - prostate [nTPM]":"5.6","Tissue RNA - rectum [nTPM]":"12.3","Tissue RNA - retina [nTPM]":"5.6","Tissue RNA - salivary gland [nTPM]":"7.2","Tissue RNA - seminal vesicle [nTPM]":"5.5","Tissue RNA - skeletal muscle [nTPM]":"44.5","Tissue RNA - skin 1 [nTPM]":"7.4","Tissue RNA - small intestine [nTPM]":"10.1","Tissue RNA - smooth muscle [nTPM]":"7.2","Tissue RNA - spinal cord [nTPM]":"3.0","Tissue RNA - spleen [nTPM]":"4.8","Tissue RNA - stomach 1 [nTPM]":"9.3","Tissue RNA - testis [nTPM]":"21.1","Tissue RNA - thalamus [nTPM]":"4.0","Tissue RNA - thymus [nTPM]":"5.4","Tissue RNA - thyroid gland [nTPM]":"6.2","Tissue RNA - tongue [nTPM]":"44.3","Tissue RNA - tonsil [nTPM]":"7.5","Tissue RNA - urinary bladder [nTPM]":"8.5","Tissue RNA - vagina [nTPM]":"6.6","Tissue RNA - white matter [nTPM]":"3.6","Cell RNA - A-431 [nTPM]":"10.1","Cell RNA - A549 [nTPM]":"19.7","Cell RNA - AF22 [nTPM]":"7.7","Cell RNA - AN3-CA [nTPM]":"11.9","Cell RNA - ASC diff [nTPM]":"7.7","Cell RNA - ASC TERT1 [nTPM]":"5.6","Cell RNA - BEWO [nTPM]":"19.5","Cell RNA - BJ [nTPM]":"12.3","Cell RNA - BJ hTERT+ [nTPM]":"8.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.6","Cell RNA - CACO-2 [nTPM]":"16.3","Cell RNA - CAPAN-2 [nTPM]":"6.6","Cell RNA - Daudi [nTPM]":"23.5","Cell RNA - EFO-21 [nTPM]":"9.8","Cell RNA - fHDF\/TERT166 [nTPM]":"13.0","Cell RNA - GAMG [nTPM]":"6.8","Cell RNA - HaCaT [nTPM]":"20.2","Cell RNA - HAP1 [nTPM]":"16.6","Cell RNA - HBEC3-KT [nTPM]":"16.3","Cell RNA - HBF TERT88 [nTPM]":"17.3","Cell RNA - HDLM-2 [nTPM]":"13.1","Cell RNA - HEK 293 [nTPM]":"15.7","Cell RNA - HEL [nTPM]":"14.5","Cell RNA - HeLa [nTPM]":"12.4","Cell RNA - Hep G2 [nTPM]":"20.0","Cell RNA - HHSteC [nTPM]":"14.2","Cell RNA - HL-60 [nTPM]":"15.5","Cell RNA - HMC-1 [nTPM]":"12.3","Cell RNA - HSkMC [nTPM]":"9.8","Cell RNA - hTCEpi [nTPM]":"19.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.0","Cell RNA - hTERT-HME1 [nTPM]":"17.6","Cell RNA - hTERT-RPE1 [nTPM]":"7.9","Cell RNA - HUVEC TERT2 [nTPM]":"11.4","Cell RNA - JURKAT [nTPM]":"15.8","Cell RNA - K-562 [nTPM]":"20.4","Cell RNA - Karpas-707 [nTPM]":"8.2","Cell RNA - LHCN-M2 [nTPM]":"9.5","Cell RNA - MCF7 [nTPM]":"13.1","Cell RNA - MOLT-4 [nTPM]":"13.5","Cell RNA - NB-4 [nTPM]":"10.5","Cell RNA - NTERA-2 [nTPM]":"12.8","Cell RNA - OE19 [nTPM]":"37.6","Cell RNA - PC-3 [nTPM]":"9.5","Cell RNA - REH [nTPM]":"10.3","Cell RNA - RH-30 [nTPM]":"28.8","Cell RNA - RPMI-8226 [nTPM]":"18.5","Cell RNA - RPTEC TERT1 [nTPM]":"15.2","Cell RNA - RT4 [nTPM]":"20.1","Cell RNA - SCLC-21H [nTPM]":"5.2","Cell RNA - SH-SY5Y [nTPM]":"9.8","Cell RNA - SiHa [nTPM]":"12.0","Cell RNA - SK-BR-3 [nTPM]":"18.5","Cell RNA - SK-MEL-30 [nTPM]":"16.5","Cell RNA - SuSa [nTPM]":"36.1","Cell RNA - T-47d [nTPM]":"9.6","Cell RNA - THP-1 [nTPM]":"9.2","Cell RNA - TIME [nTPM]":"9.9","Cell RNA - U-138 MG [nTPM]":"8.9","Cell RNA - U-2 OS [nTPM]":"8.0","Cell RNA - U-2197 [nTPM]":"9.9","Cell RNA - U-251 MG [nTPM]":"15.8","Cell RNA - U-266\/70 [nTPM]":"10.1","Cell RNA - U-266\/84 [nTPM]":"15.6","Cell RNA - U-698 [nTPM]":"11.2","Cell RNA - U-87 MG [nTPM]":"14.9","Cell RNA - U-937 [nTPM]":"15.7","Cell RNA - WM-115 [nTPM]":"11.9","Blood RNA - basophil [nTPM]":"3.8","Blood RNA - classical monocyte [nTPM]":"11.3","Blood RNA - eosinophil [nTPM]":"4.4","Blood RNA - gdT-cell [nTPM]":"9.8","Blood RNA - intermediate monocyte [nTPM]":"16.1","Blood RNA - MAIT T-cell [nTPM]":"10.6","Blood RNA - memory B-cell [nTPM]":"13.2","Blood RNA - memory CD4 T-cell [nTPM]":"11.3","Blood RNA - memory CD8 T-cell [nTPM]":"10.5","Blood RNA - myeloid DC [nTPM]":"14.9","Blood RNA - naive B-cell [nTPM]":"9.2","Blood RNA - naive CD4 T-cell [nTPM]":"11.9","Blood RNA - naive CD8 T-cell [nTPM]":"11.5","Blood RNA - neutrophil [nTPM]":"1.2","Blood RNA - NK-cell [nTPM]":"10.0","Blood RNA - non-classical monocyte [nTPM]":"13.9","Blood RNA - plasmacytoid DC [nTPM]":"4.6","Blood RNA - T-reg [nTPM]":"20.1","Blood RNA - total PBMC [nTPM]":"11.0","Brain RNA - amygdala [nTPM]":"3.1","Brain RNA - basal ganglia [nTPM]":"2.9","Brain RNA - cerebellum [nTPM]":"4.1","Brain RNA - cerebral cortex [nTPM]":"4.4","Brain RNA - hippocampal formation [nTPM]":"3.3","Brain RNA - hypothalamus [nTPM]":"3.9","Brain RNA - medulla oblongata [nTPM]":"3.8","Brain RNA - midbrain [nTPM]":"3.5","Brain RNA - pons [nTPM]":"3.5","Brain RNA - spinal cord [nTPM]":"3.0","Brain RNA - thalamus [nTPM]":"4.0","Brain RNA - white matter [nTPM]":"3.6","Single Cell Type RNA - Adipocytes [nTPM]":"5.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.7","Single Cell Type RNA - Astrocytes [nTPM]":"25.8","Single Cell Type RNA - B-cells [nTPM]":"9.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"7.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"88.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"7.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.7","Single Cell Type RNA - dendritic cells [nTPM]":"5.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"41.1","Single Cell Type RNA - Ductal cells [nTPM]":"9.1","Single Cell Type RNA - Early spermatids [nTPM]":"41.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.6","Single Cell Type RNA - Endothelial cells [nTPM]":"7.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.6","Single Cell Type RNA - Erythroid cells [nTPM]":"13.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"33.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.5","Single Cell Type RNA - Fibroblasts [nTPM]":"8.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.4","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"7.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"9.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"43.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.4","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"4.4","Single Cell Type RNA - Langerhans cells [nTPM]":"4.7","Single Cell Type RNA - Late spermatids [nTPM]":"81.0","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"6.7","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"22.5","Single Cell Type RNA - monocytes [nTPM]":"6.3","Single Cell Type RNA - Muller glia cells [nTPM]":"4.6","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"34.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"26.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.8","Single Cell Type RNA - Paneth cells [nTPM]":"11.4","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"12.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"26.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.5","Single Cell Type RNA - Spermatocytes [nTPM]":"22.8","Single Cell Type RNA - Spermatogonia [nTPM]":"19.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.1","Single Cell Type RNA - T-cells [nTPM]":"8.6","Single Cell Type RNA - Theca cells [nTPM]":"6.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.9","Single Cell Type RNA - Urothelial cells [nTPM]":"13.7"},{"Gene":"COX4I1","Gene synonym":["COX4","COX4-1"],"Ensembl":"ENSG00000131143","Gene description":"Cytochrome c oxidase subunit 4I1","Uniprot":["P13073"],"Chromosome":"16","Position":"85798633-85807068","Protein class":["Disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002485","CAB004080"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"55000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB004080":"AB_2085427","HPA002485":"AB_1078559"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.14e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.56e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Tissue RNA - adipose tissue [nTPM]":"473.1","Tissue RNA - adrenal gland [nTPM]":"393.5","Tissue RNA - amygdala [nTPM]":"874.4","Tissue RNA - appendix [nTPM]":"232.5","Tissue RNA - basal ganglia [nTPM]":"881.4","Tissue RNA - bone marrow [nTPM]":"583.2","Tissue RNA - breast [nTPM]":"437.1","Tissue RNA - cerebellum [nTPM]":"896.5","Tissue RNA - cerebral cortex [nTPM]":"971.9","Tissue RNA - cervix [nTPM]":"373.1","Tissue RNA - choroid plexus [nTPM]":"882.6","Tissue RNA - colon [nTPM]":"690.5","Tissue RNA - duodenum [nTPM]":"585.9","Tissue RNA - endometrium 1 [nTPM]":"301.8","Tissue RNA - epididymis [nTPM]":"478.8","Tissue RNA - esophagus [nTPM]":"597.2","Tissue RNA - fallopian tube [nTPM]":"355.8","Tissue RNA - gallbladder [nTPM]":"246.9","Tissue RNA - heart muscle [nTPM]":"2047.0","Tissue RNA - hippocampal formation [nTPM]":"869.5","Tissue RNA - hypothalamus [nTPM]":"909.5","Tissue RNA - kidney [nTPM]":"632.7","Tissue RNA - liver [nTPM]":"611.2","Tissue RNA - lung [nTPM]":"318.6","Tissue RNA - lymph node [nTPM]":"412.8","Tissue RNA - medulla oblongata [nTPM]":"896.4","Tissue RNA - midbrain [nTPM]":"891.1","Tissue RNA - ovary [nTPM]":"366.2","Tissue RNA - pancreas [nTPM]":"490.4","Tissue RNA - parathyroid gland [nTPM]":"900.7","Tissue RNA - pituitary gland [nTPM]":"362.1","Tissue RNA - placenta [nTPM]":"256.7","Tissue RNA - pons [nTPM]":"908.6","Tissue RNA - prostate [nTPM]":"377.1","Tissue RNA - rectum [nTPM]":"707.7","Tissue RNA - retina [nTPM]":"261.2","Tissue RNA - salivary gland [nTPM]":"421.2","Tissue RNA - seminal vesicle [nTPM]":"312.3","Tissue RNA - skeletal muscle [nTPM]":"1333.3","Tissue RNA - skin 1 [nTPM]":"552.5","Tissue RNA - small intestine [nTPM]":"529.5","Tissue RNA - smooth muscle [nTPM]":"301.4","Tissue RNA - spinal cord [nTPM]":"877.2","Tissue RNA - spleen [nTPM]":"405.9","Tissue RNA - stomach 1 [nTPM]":"650.3","Tissue RNA - testis [nTPM]":"191.1","Tissue RNA - thalamus [nTPM]":"922.9","Tissue RNA - thymus [nTPM]":"479.9","Tissue RNA - thyroid gland [nTPM]":"361.5","Tissue RNA - tongue [nTPM]":"2063.3","Tissue RNA - tonsil [nTPM]":"538.7","Tissue RNA - urinary bladder [nTPM]":"422.6","Tissue RNA - vagina [nTPM]":"420.9","Tissue RNA - white matter [nTPM]":"881.0","Cell RNA - A-431 [nTPM]":"433.7","Cell RNA - A549 [nTPM]":"677.7","Cell RNA - AF22 [nTPM]":"460.2","Cell RNA - AN3-CA [nTPM]":"616.8","Cell RNA - ASC diff [nTPM]":"823.6","Cell RNA - ASC TERT1 [nTPM]":"761.2","Cell RNA - BEWO [nTPM]":"785.7","Cell RNA - BJ [nTPM]":"379.6","Cell RNA - BJ hTERT+ [nTPM]":"771.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"702.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"346.7","Cell RNA - CACO-2 [nTPM]":"1170.2","Cell RNA - CAPAN-2 [nTPM]":"636.6","Cell RNA - Daudi [nTPM]":"698.6","Cell RNA - EFO-21 [nTPM]":"454.2","Cell RNA - fHDF\/TERT166 [nTPM]":"610.5","Cell RNA - GAMG [nTPM]":"389.9","Cell RNA - HaCaT [nTPM]":"855.1","Cell RNA - HAP1 [nTPM]":"657.2","Cell RNA - HBEC3-KT [nTPM]":"765.3","Cell RNA - HBF TERT88 [nTPM]":"622.2","Cell RNA - HDLM-2 [nTPM]":"238.7","Cell RNA - HEK 293 [nTPM]":"678.1","Cell RNA - HEL [nTPM]":"392.9","Cell RNA - HeLa [nTPM]":"554.8","Cell RNA - Hep G2 [nTPM]":"1093.8","Cell RNA - HHSteC [nTPM]":"741.9","Cell RNA - HL-60 [nTPM]":"362.9","Cell RNA - HMC-1 [nTPM]":"282.0","Cell RNA - HSkMC [nTPM]":"893.1","Cell RNA - hTCEpi [nTPM]":"1162.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"579.2","Cell RNA - hTERT-HME1 [nTPM]":"786.0","Cell RNA - hTERT-RPE1 [nTPM]":"739.1","Cell RNA - HUVEC TERT2 [nTPM]":"746.4","Cell RNA - JURKAT [nTPM]":"563.6","Cell RNA - K-562 [nTPM]":"672.3","Cell RNA - Karpas-707 [nTPM]":"280.4","Cell RNA - LHCN-M2 [nTPM]":"602.5","Cell RNA - MCF7 [nTPM]":"1510.6","Cell RNA - MOLT-4 [nTPM]":"730.9","Cell RNA - NB-4 [nTPM]":"1116.7","Cell RNA - NTERA-2 [nTPM]":"623.0","Cell RNA - OE19 [nTPM]":"954.1","Cell RNA - PC-3 [nTPM]":"796.3","Cell RNA - REH [nTPM]":"816.9","Cell RNA - RH-30 [nTPM]":"287.5","Cell RNA - RPMI-8226 [nTPM]":"616.7","Cell RNA - RPTEC TERT1 [nTPM]":"1066.7","Cell RNA - RT4 [nTPM]":"840.2","Cell RNA - SCLC-21H [nTPM]":"543.2","Cell RNA - SH-SY5Y [nTPM]":"441.1","Cell RNA - SiHa [nTPM]":"807.4","Cell RNA - SK-BR-3 [nTPM]":"513.2","Cell RNA - SK-MEL-30 [nTPM]":"656.2","Cell RNA - SuSa [nTPM]":"489.6","Cell RNA - T-47d [nTPM]":"753.2","Cell RNA - THP-1 [nTPM]":"996.6","Cell RNA - TIME [nTPM]":"529.9","Cell RNA - U-138 MG [nTPM]":"355.5","Cell RNA - U-2 OS [nTPM]":"409.5","Cell RNA - U-2197 [nTPM]":"330.7","Cell RNA - U-251 MG [nTPM]":"419.0","Cell RNA - U-266\/70 [nTPM]":"561.4","Cell RNA - U-266\/84 [nTPM]":"562.5","Cell RNA - U-698 [nTPM]":"1646.3","Cell RNA - U-87 MG [nTPM]":"542.4","Cell RNA - U-937 [nTPM]":"702.2","Cell RNA - WM-115 [nTPM]":"410.6","Blood RNA - basophil [nTPM]":"633.9","Blood RNA - classical monocyte [nTPM]":"1373.2","Blood RNA - eosinophil [nTPM]":"805.2","Blood RNA - gdT-cell [nTPM]":"700.3","Blood RNA - intermediate monocyte [nTPM]":"1199.6","Blood RNA - MAIT T-cell [nTPM]":"868.1","Blood RNA - memory B-cell [nTPM]":"1302.9","Blood RNA - memory CD4 T-cell [nTPM]":"930.5","Blood RNA - memory CD8 T-cell [nTPM]":"833.2","Blood RNA - myeloid DC [nTPM]":"1480.8","Blood RNA - naive B-cell [nTPM]":"1231.2","Blood RNA - naive CD4 T-cell [nTPM]":"1169.3","Blood RNA - naive CD8 T-cell [nTPM]":"968.8","Blood RNA - neutrophil [nTPM]":"513.9","Blood RNA - NK-cell [nTPM]":"840.6","Blood RNA - non-classical monocyte [nTPM]":"1089.3","Blood RNA - plasmacytoid DC [nTPM]":"1105.6","Blood RNA - T-reg [nTPM]":"1106.1","Blood RNA - total PBMC [nTPM]":"2815.9","Brain RNA - amygdala [nTPM]":"874.4","Brain RNA - basal ganglia [nTPM]":"881.4","Brain RNA - cerebellum [nTPM]":"896.5","Brain RNA - cerebral cortex [nTPM]":"971.9","Brain RNA - hippocampal formation [nTPM]":"869.5","Brain RNA - hypothalamus [nTPM]":"909.5","Brain RNA - medulla oblongata [nTPM]":"896.4","Brain RNA - midbrain [nTPM]":"891.1","Brain RNA - pons [nTPM]":"908.6","Brain RNA - spinal cord [nTPM]":"877.2","Brain RNA - thalamus [nTPM]":"922.9","Brain RNA - white matter [nTPM]":"881.0","Single Cell Type RNA - Adipocytes [nTPM]":"552.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"275.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"398.1","Single Cell Type RNA - Astrocytes [nTPM]":"45.1","Single Cell Type RNA - B-cells [nTPM]":"925.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1129.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1242.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2031.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1121.8","Single Cell Type RNA - Bipolar cells [nTPM]":"280.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"1365.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1553.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3479.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"1086.6","Single Cell Type RNA - Club cells [nTPM]":"942.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"632.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"131.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1223.1","Single Cell Type RNA - dendritic cells [nTPM]":"714.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"1863.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"2752.8","Single Cell Type RNA - Ductal cells [nTPM]":"1091.1","Single Cell Type RNA - Early spermatids [nTPM]":"539.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"480.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"468.0","Single Cell Type RNA - Endothelial cells [nTPM]":"629.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1009.6","Single Cell Type RNA - Erythroid cells [nTPM]":"524.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"44.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1316.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1094.7","Single Cell Type RNA - Fibroblasts [nTPM]":"591.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"813.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"575.6","Single Cell Type RNA - granulocytes [nTPM]":"521.4","Single Cell Type RNA - Granulosa cells [nTPM]":"554.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"660.7","Single Cell Type RNA - Hepatocytes [nTPM]":"1314.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"1602.3","Single Cell Type RNA - Horizontal cells [nTPM]":"212.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"51.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1782.5","Single Cell Type RNA - Ionocytes [nTPM]":"1125.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1488.5","Single Cell Type RNA - Langerhans cells [nTPM]":"1376.5","Single Cell Type RNA - Late spermatids [nTPM]":"1155.4","Single Cell Type RNA - Leydig cells [nTPM]":"498.9","Single Cell Type RNA - Macrophages [nTPM]":"1010.5","Single Cell Type RNA - Melanocytes [nTPM]":"1145.5","Single Cell Type RNA - Microglial cells [nTPM]":"35.6","Single Cell Type RNA - monocytes [nTPM]":"1451.7","Single Cell Type RNA - Muller glia cells [nTPM]":"562.9","Single Cell Type RNA - NK-cells [nTPM]":"785.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"35.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"65.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1463.7","Single Cell Type RNA - Paneth cells [nTPM]":"1950.7","Single Cell Type RNA - Peritubular cells [nTPM]":"357.7","Single Cell Type RNA - Plasma cells [nTPM]":"726.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1370.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3811.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2936.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"545.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"349.9","Single Cell Type RNA - Sertoli cells [nTPM]":"355.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"481.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"678.0","Single Cell Type RNA - Spermatocytes [nTPM]":"358.6","Single Cell Type RNA - Spermatogonia [nTPM]":"321.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1721.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1361.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1481.9","Single Cell Type RNA - T-cells [nTPM]":"816.5","Single Cell Type RNA - Theca cells [nTPM]":"1020.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2147.9","Single Cell Type RNA - Urothelial cells [nTPM]":"1941.7"},{"Gene":"COX4I2","Gene synonym":["COX4-2","COX4B","COX4L2","COXIV-2","dJ857M17.2"],"Ensembl":"ENSG00000131055","Gene description":"Cytochrome c oxidase subunit 4I2","Uniprot":["Q96KJ9"],"Chromosome":"20","Position":"31637912-31645006","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"49.1","placenta":"115.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Sertoli cells":"414.2","Smooth muscle cells":"191.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"SH-SY5Y":"1.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.04e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.78e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-2"},"Tissue RNA - adipose tissue [nTPM]":"19.1","Tissue RNA - adrenal gland [nTPM]":"1.1","Tissue RNA - amygdala [nTPM]":"6.7","Tissue RNA - appendix [nTPM]":"1.7","Tissue RNA - basal ganglia [nTPM]":"6.7","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"15.9","Tissue RNA - cerebellum [nTPM]":"6.5","Tissue RNA - cerebral cortex [nTPM]":"9.1","Tissue RNA - cervix [nTPM]":"4.8","Tissue RNA - choroid plexus [nTPM]":"6.1","Tissue RNA - colon [nTPM]":"4.7","Tissue RNA - duodenum [nTPM]":"1.9","Tissue RNA - endometrium 1 [nTPM]":"7.5","Tissue RNA - epididymis [nTPM]":"3.9","Tissue RNA - esophagus [nTPM]":"5.4","Tissue RNA - fallopian tube [nTPM]":"4.9","Tissue RNA - gallbladder [nTPM]":"10.6","Tissue RNA - heart muscle [nTPM]":"39.7","Tissue RNA - hippocampal formation [nTPM]":"6.5","Tissue RNA - hypothalamus [nTPM]":"6.7","Tissue RNA - kidney [nTPM]":"10.9","Tissue RNA - liver [nTPM]":"1.1","Tissue RNA - lung [nTPM]":"49.1","Tissue RNA - lymph node [nTPM]":"4.7","Tissue RNA - medulla oblongata [nTPM]":"6.8","Tissue RNA - midbrain [nTPM]":"7.0","Tissue RNA - ovary [nTPM]":"2.9","Tissue RNA - pancreas [nTPM]":"2.3","Tissue RNA - parathyroid gland [nTPM]":"9.3","Tissue RNA - pituitary gland [nTPM]":"2.2","Tissue RNA - placenta [nTPM]":"115.4","Tissue RNA - pons [nTPM]":"7.0","Tissue RNA - prostate [nTPM]":"10.1","Tissue RNA - rectum [nTPM]":"2.7","Tissue RNA - retina [nTPM]":"1.1","Tissue RNA - salivary gland [nTPM]":"3.6","Tissue RNA - seminal vesicle [nTPM]":"4.7","Tissue RNA - skeletal muscle [nTPM]":"8.7","Tissue RNA - skin 1 [nTPM]":"4.9","Tissue RNA - small intestine [nTPM]":"5.8","Tissue RNA - smooth muscle [nTPM]":"7.1","Tissue RNA - spinal cord [nTPM]":"6.6","Tissue RNA - spleen [nTPM]":"1.7","Tissue RNA - stomach 1 [nTPM]":"4.2","Tissue RNA - testis [nTPM]":"1.5","Tissue RNA - thalamus [nTPM]":"7.0","Tissue RNA - thymus [nTPM]":"1.8","Tissue RNA - thyroid gland [nTPM]":"14.7","Tissue RNA - tongue [nTPM]":"19.4","Tissue RNA - tonsil [nTPM]":"3.0","Tissue RNA - urinary bladder [nTPM]":"7.7","Tissue RNA - vagina [nTPM]":"6.7","Tissue RNA - white matter [nTPM]":"6.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"1.8","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"6.7","Brain RNA - basal ganglia [nTPM]":"6.7","Brain RNA - cerebellum [nTPM]":"6.5","Brain RNA - cerebral cortex [nTPM]":"9.1","Brain RNA - hippocampal formation [nTPM]":"6.5","Brain RNA - hypothalamus [nTPM]":"6.7","Brain RNA - medulla oblongata [nTPM]":"6.8","Brain RNA - midbrain [nTPM]":"7.0","Brain RNA - pons [nTPM]":"7.0","Brain RNA - spinal cord [nTPM]":"6.6","Brain RNA - thalamus [nTPM]":"7.0","Brain RNA - white matter [nTPM]":"6.6","Single Cell Type RNA - Adipocytes [nTPM]":"55.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"23.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"9.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"7.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"3.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"414.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"191.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"1.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"COX5A","Gene synonym":[],"Ensembl":"ENSG00000178741","Gene description":"Cytochrome c oxidase subunit 5A","Uniprot":["P20674"],"Chromosome":"15","Position":"74919791-74938083","Protein class":["Disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"1749.5","skeletal muscle":"1609.7","tongue":"1735.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"1645.3","Distal tubular cells":"1475.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027526"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"530000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA027526":"AB_10602802"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.15e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.06e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-3"},"Tissue RNA - adipose tissue [nTPM]":"175.6","Tissue RNA - adrenal gland [nTPM]":"176.7","Tissue RNA - amygdala [nTPM]":"187.1","Tissue RNA - appendix [nTPM]":"105.1","Tissue RNA - basal ganglia [nTPM]":"189.5","Tissue RNA - bone marrow [nTPM]":"148.5","Tissue RNA - breast [nTPM]":"150.8","Tissue RNA - cerebellum [nTPM]":"231.1","Tissue RNA - cerebral cortex [nTPM]":"258.1","Tissue RNA - cervix [nTPM]":"109.8","Tissue RNA - choroid plexus [nTPM]":"201.3","Tissue RNA - colon [nTPM]":"454.2","Tissue RNA - duodenum [nTPM]":"326.9","Tissue RNA - endometrium 1 [nTPM]":"98.2","Tissue RNA - epididymis [nTPM]":"110.7","Tissue RNA - esophagus [nTPM]":"293.0","Tissue RNA - fallopian tube [nTPM]":"89.3","Tissue RNA - gallbladder [nTPM]":"67.8","Tissue RNA - heart muscle [nTPM]":"1749.5","Tissue RNA - hippocampal formation [nTPM]":"193.1","Tissue RNA - hypothalamus [nTPM]":"229.3","Tissue RNA - kidney [nTPM]":"373.5","Tissue RNA - liver [nTPM]":"349.6","Tissue RNA - lung [nTPM]":"133.0","Tissue RNA - lymph node [nTPM]":"125.6","Tissue RNA - medulla oblongata [nTPM]":"216.1","Tissue RNA - midbrain [nTPM]":"207.5","Tissue RNA - ovary [nTPM]":"71.1","Tissue RNA - pancreas [nTPM]":"259.3","Tissue RNA - parathyroid gland [nTPM]":"385.3","Tissue RNA - pituitary gland [nTPM]":"141.1","Tissue RNA - placenta [nTPM]":"88.0","Tissue RNA - pons [nTPM]":"208.8","Tissue RNA - prostate [nTPM]":"118.4","Tissue RNA - rectum [nTPM]":"398.2","Tissue RNA - retina [nTPM]":"194.1","Tissue RNA - salivary gland [nTPM]":"211.2","Tissue RNA - seminal vesicle [nTPM]":"99.2","Tissue RNA - skeletal muscle [nTPM]":"1609.7","Tissue RNA - skin 1 [nTPM]":"169.0","Tissue RNA - small intestine [nTPM]":"269.6","Tissue RNA - smooth muscle [nTPM]":"95.0","Tissue RNA - spinal cord [nTPM]":"194.8","Tissue RNA - spleen [nTPM]":"150.8","Tissue RNA - stomach 1 [nTPM]":"306.8","Tissue RNA - testis [nTPM]":"217.8","Tissue RNA - thalamus [nTPM]":"220.4","Tissue RNA - thymus [nTPM]":"150.7","Tissue RNA - thyroid gland [nTPM]":"141.5","Tissue RNA - tongue [nTPM]":"1735.8","Tissue RNA - tonsil [nTPM]":"197.9","Tissue RNA - urinary bladder [nTPM]":"141.2","Tissue RNA - vagina [nTPM]":"146.3","Tissue RNA - white matter [nTPM]":"193.8","Cell RNA - A-431 [nTPM]":"300.4","Cell RNA - A549 [nTPM]":"309.1","Cell RNA - AF22 [nTPM]":"376.8","Cell RNA - AN3-CA [nTPM]":"331.1","Cell RNA - ASC diff [nTPM]":"227.2","Cell RNA - ASC TERT1 [nTPM]":"260.2","Cell RNA - BEWO [nTPM]":"443.1","Cell RNA - BJ [nTPM]":"262.7","Cell RNA - BJ hTERT+ [nTPM]":"222.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"317.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"294.8","Cell RNA - CACO-2 [nTPM]":"346.0","Cell RNA - CAPAN-2 [nTPM]":"352.1","Cell RNA - Daudi [nTPM]":"700.0","Cell RNA - EFO-21 [nTPM]":"322.0","Cell RNA - fHDF\/TERT166 [nTPM]":"219.5","Cell RNA - GAMG [nTPM]":"387.8","Cell RNA - HaCaT [nTPM]":"567.7","Cell RNA - HAP1 [nTPM]":"898.3","Cell RNA - HBEC3-KT [nTPM]":"368.4","Cell RNA - HBF TERT88 [nTPM]":"263.7","Cell RNA - HDLM-2 [nTPM]":"401.0","Cell RNA - HEK 293 [nTPM]":"906.2","Cell RNA - HEL [nTPM]":"566.6","Cell RNA - HeLa [nTPM]":"299.7","Cell RNA - Hep G2 [nTPM]":"436.0","Cell RNA - HHSteC [nTPM]":"283.9","Cell RNA - HL-60 [nTPM]":"642.7","Cell RNA - HMC-1 [nTPM]":"335.0","Cell RNA - HSkMC [nTPM]":"266.6","Cell RNA - hTCEpi [nTPM]":"389.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"198.3","Cell RNA - hTERT-HME1 [nTPM]":"445.1","Cell RNA - hTERT-RPE1 [nTPM]":"217.4","Cell RNA - HUVEC TERT2 [nTPM]":"377.7","Cell RNA - JURKAT [nTPM]":"450.0","Cell RNA - K-562 [nTPM]":"522.2","Cell RNA - Karpas-707 [nTPM]":"429.9","Cell RNA - LHCN-M2 [nTPM]":"321.2","Cell RNA - MCF7 [nTPM]":"222.4","Cell RNA - MOLT-4 [nTPM]":"558.8","Cell RNA - NB-4 [nTPM]":"494.6","Cell RNA - NTERA-2 [nTPM]":"408.7","Cell RNA - OE19 [nTPM]":"575.8","Cell RNA - PC-3 [nTPM]":"540.1","Cell RNA - REH [nTPM]":"499.0","Cell RNA - RH-30 [nTPM]":"369.7","Cell RNA - RPMI-8226 [nTPM]":"778.4","Cell RNA - RPTEC TERT1 [nTPM]":"469.8","Cell RNA - RT4 [nTPM]":"472.4","Cell RNA - SCLC-21H [nTPM]":"570.5","Cell RNA - SH-SY5Y [nTPM]":"250.1","Cell RNA - SiHa [nTPM]":"396.6","Cell RNA - SK-BR-3 [nTPM]":"569.2","Cell RNA - SK-MEL-30 [nTPM]":"871.3","Cell RNA - SuSa [nTPM]":"407.6","Cell RNA - T-47d [nTPM]":"286.3","Cell RNA - THP-1 [nTPM]":"507.6","Cell RNA - TIME [nTPM]":"274.3","Cell RNA - U-138 MG [nTPM]":"241.4","Cell RNA - U-2 OS [nTPM]":"238.7","Cell RNA - U-2197 [nTPM]":"303.9","Cell RNA - U-251 MG [nTPM]":"421.1","Cell RNA - U-266\/70 [nTPM]":"508.4","Cell RNA - U-266\/84 [nTPM]":"1000.3","Cell RNA - U-698 [nTPM]":"759.0","Cell RNA - U-87 MG [nTPM]":"258.2","Cell RNA - U-937 [nTPM]":"836.1","Cell RNA - WM-115 [nTPM]":"224.5","Blood RNA - basophil [nTPM]":"332.4","Blood RNA - classical monocyte [nTPM]":"361.5","Blood RNA - eosinophil [nTPM]":"210.2","Blood RNA - gdT-cell [nTPM]":"198.1","Blood RNA - intermediate monocyte [nTPM]":"465.6","Blood RNA - MAIT T-cell [nTPM]":"238.6","Blood RNA - memory B-cell [nTPM]":"296.4","Blood RNA - memory CD4 T-cell [nTPM]":"242.4","Blood RNA - memory CD8 T-cell [nTPM]":"235.7","Blood RNA - myeloid DC [nTPM]":"452.9","Blood RNA - naive B-cell [nTPM]":"227.3","Blood RNA - naive CD4 T-cell [nTPM]":"171.6","Blood RNA - naive CD8 T-cell [nTPM]":"198.0","Blood RNA - neutrophil [nTPM]":"87.4","Blood RNA - NK-cell [nTPM]":"354.9","Blood RNA - non-classical monocyte [nTPM]":"432.7","Blood RNA - plasmacytoid DC [nTPM]":"365.2","Blood RNA - T-reg [nTPM]":"372.6","Blood RNA - total PBMC [nTPM]":"426.4","Brain RNA - amygdala [nTPM]":"187.1","Brain RNA - basal ganglia [nTPM]":"189.5","Brain RNA - cerebellum [nTPM]":"231.1","Brain RNA - cerebral cortex [nTPM]":"258.1","Brain RNA - hippocampal formation [nTPM]":"193.1","Brain RNA - hypothalamus [nTPM]":"229.3","Brain RNA - medulla oblongata [nTPM]":"216.1","Brain RNA - midbrain [nTPM]":"207.5","Brain RNA - pons [nTPM]":"208.8","Brain RNA - spinal cord [nTPM]":"194.8","Brain RNA - thalamus [nTPM]":"220.4","Brain RNA - white matter [nTPM]":"193.8","Single Cell Type RNA - Adipocytes [nTPM]":"120.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"99.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"119.6","Single Cell Type RNA - Astrocytes [nTPM]":"20.5","Single Cell Type RNA - B-cells [nTPM]":"166.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"158.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"235.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"623.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"151.4","Single Cell Type RNA - Bipolar cells [nTPM]":"113.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"202.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"313.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1645.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"221.6","Single Cell Type RNA - Club cells [nTPM]":"324.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"171.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"502.8","Single Cell Type RNA - dendritic cells [nTPM]":"162.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"987.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1475.2","Single Cell Type RNA - Ductal cells [nTPM]":"407.5","Single Cell Type RNA - Early spermatids [nTPM]":"1046.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"199.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"124.3","Single Cell Type RNA - Endothelial cells [nTPM]":"163.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"461.4","Single Cell Type RNA - Erythroid cells [nTPM]":"227.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"436.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"528.2","Single Cell Type RNA - Fibroblasts [nTPM]":"156.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"247.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"192.8","Single Cell Type RNA - granulocytes [nTPM]":"104.0","Single Cell Type RNA - Granulosa cells [nTPM]":"143.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"117.8","Single Cell Type RNA - Hepatocytes [nTPM]":"471.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"571.5","Single Cell Type RNA - Horizontal cells [nTPM]":"92.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"890.5","Single Cell Type RNA - Ionocytes [nTPM]":"496.4","Single Cell Type RNA - Kupffer cells [nTPM]":"286.0","Single Cell Type RNA - Langerhans cells [nTPM]":"209.1","Single Cell Type RNA - Late spermatids [nTPM]":"819.6","Single Cell Type RNA - Leydig cells [nTPM]":"100.3","Single Cell Type RNA - Macrophages [nTPM]":"238.6","Single Cell Type RNA - Melanocytes [nTPM]":"250.8","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"413.7","Single Cell Type RNA - Muller glia cells [nTPM]":"159.9","Single Cell Type RNA - NK-cells [nTPM]":"162.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"412.1","Single Cell Type RNA - Paneth cells [nTPM]":"817.3","Single Cell Type RNA - Peritubular cells [nTPM]":"85.7","Single Cell Type RNA - Plasma cells [nTPM]":"350.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"319.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1276.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"921.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"242.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"176.8","Single Cell Type RNA - Sertoli cells [nTPM]":"92.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"139.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"590.9","Single Cell Type RNA - Spermatocytes [nTPM]":"523.0","Single Cell Type RNA - Spermatogonia [nTPM]":"253.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"371.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"159.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"511.0","Single Cell Type RNA - T-cells [nTPM]":"144.2","Single Cell Type RNA - Theca cells [nTPM]":"216.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1045.6","Single Cell Type RNA - Urothelial cells [nTPM]":"393.3"},{"Gene":"COX6A2","Gene synonym":[],"Ensembl":"ENSG00000156885","Gene description":"Cytochrome c oxidase subunit 6A2","Uniprot":["Q02221"],"Chromosome":"16","Position":"31427731-31428360","Protein class":["Disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"46","RNA tissue specific nTPM":{"heart muscle":"3905.3","skeletal muscle":"6742.0","tongue":"2096.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"18","RNA single cell type specific nTPM":{"Cardiomyocytes":"4861.8"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"head and neck cancer":"9.3","liver cancer":"2.9","prostate cancer":"3.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"150","RNA blood cell specific nTPM":{"NK-cell":"15.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"150","RNA blood lineage specific nTPM":{"NK-cells":"15.0"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"U-266\/84":"13.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"1.9","Tissue RNA - adrenal gland [nTPM]":"0.9","Tissue RNA - amygdala [nTPM]":"1.8","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"1.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"2.9","Tissue RNA - cerebellum [nTPM]":"2.3","Tissue RNA - cerebral cortex [nTPM]":"2.3","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"1.4","Tissue RNA - duodenum [nTPM]":"1.1","Tissue RNA - endometrium 1 [nTPM]":"1.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"74.8","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"3905.3","Tissue RNA - hippocampal formation [nTPM]":"0.9","Tissue RNA - hypothalamus [nTPM]":"2.1","Tissue RNA - kidney [nTPM]":"4.5","Tissue RNA - liver [nTPM]":"15.9","Tissue RNA - lung [nTPM]":"3.3","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"1.6","Tissue RNA - midbrain [nTPM]":"2.6","Tissue RNA - ovary [nTPM]":"1.2","Tissue RNA - pancreas [nTPM]":"3.0","Tissue RNA - parathyroid gland [nTPM]":"2.9","Tissue RNA - pituitary gland [nTPM]":"11.9","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"7.3","Tissue RNA - prostate [nTPM]":"38.9","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"1.0","Tissue RNA - salivary gland [nTPM]":"92.1","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"6742.0","Tissue RNA - skin 1 [nTPM]":"3.5","Tissue RNA - small intestine [nTPM]":"1.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"1.3","Tissue RNA - testis [nTPM]":"1.3","Tissue RNA - thalamus [nTPM]":"2.6","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"2.0","Tissue RNA - tongue [nTPM]":"2096.1","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"1.4","Tissue RNA - white matter [nTPM]":"1.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"3.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"1.2","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"13.8","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"15.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"1.8","Brain RNA - basal ganglia [nTPM]":"1.3","Brain RNA - cerebellum [nTPM]":"2.3","Brain RNA - cerebral cortex [nTPM]":"2.3","Brain RNA - hippocampal formation [nTPM]":"0.9","Brain RNA - hypothalamus [nTPM]":"2.1","Brain RNA - medulla oblongata [nTPM]":"1.6","Brain RNA - midbrain [nTPM]":"2.6","Brain RNA - pons [nTPM]":"7.3","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"2.6","Brain RNA - white matter [nTPM]":"1.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4861.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"48.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"96.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"75.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.9","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"1.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"24.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"258.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"53.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"2.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"COX8A","Gene synonym":["COX","COX8","COX8-2","COX8L","VIII","VIII-L"],"Ensembl":"ENSG00000176340","Gene description":"Cytochrome c oxidase subunit 8A","Uniprot":["P10176"],"Chromosome":"11","Position":"63974620-63976543","Protein class":["Disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"2341.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055942"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA055942":"AB_2682979"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.49e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.51e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-2"},"Tissue RNA - adipose tissue [nTPM]":"322.0","Tissue RNA - adrenal gland [nTPM]":"443.8","Tissue RNA - amygdala [nTPM]":"421.6","Tissue RNA - appendix [nTPM]":"134.1","Tissue RNA - basal ganglia [nTPM]":"435.5","Tissue RNA - bone marrow [nTPM]":"292.0","Tissue RNA - breast [nTPM]":"286.8","Tissue RNA - cerebellum [nTPM]":"470.0","Tissue RNA - cerebral cortex [nTPM]":"544.7","Tissue RNA - cervix [nTPM]":"259.3","Tissue RNA - choroid plexus [nTPM]":"524.0","Tissue RNA - colon [nTPM]":"516.1","Tissue RNA - duodenum [nTPM]":"337.8","Tissue RNA - endometrium 1 [nTPM]":"236.1","Tissue RNA - epididymis [nTPM]":"121.2","Tissue RNA - esophagus [nTPM]":"612.5","Tissue RNA - fallopian tube [nTPM]":"246.8","Tissue RNA - gallbladder [nTPM]":"78.4","Tissue RNA - heart muscle [nTPM]":"1287.8","Tissue RNA - hippocampal formation [nTPM]":"415.9","Tissue RNA - hypothalamus [nTPM]":"469.2","Tissue RNA - kidney [nTPM]":"771.1","Tissue RNA - liver [nTPM]":"449.9","Tissue RNA - lung [nTPM]":"265.4","Tissue RNA - lymph node [nTPM]":"119.9","Tissue RNA - medulla oblongata [nTPM]":"421.5","Tissue RNA - midbrain [nTPM]":"420.4","Tissue RNA - ovary [nTPM]":"248.0","Tissue RNA - pancreas [nTPM]":"275.7","Tissue RNA - parathyroid gland [nTPM]":"366.3","Tissue RNA - pituitary gland [nTPM]":"373.9","Tissue RNA - placenta [nTPM]":"105.7","Tissue RNA - pons [nTPM]":"414.7","Tissue RNA - prostate [nTPM]":"316.0","Tissue RNA - rectum [nTPM]":"250.2","Tissue RNA - retina [nTPM]":"149.5","Tissue RNA - salivary gland [nTPM]":"362.1","Tissue RNA - seminal vesicle [nTPM]":"223.8","Tissue RNA - skeletal muscle [nTPM]":"1523.9","Tissue RNA - skin 1 [nTPM]":"362.0","Tissue RNA - small intestine [nTPM]":"381.5","Tissue RNA - smooth muscle [nTPM]":"132.3","Tissue RNA - spinal cord [nTPM]":"427.7","Tissue RNA - spleen [nTPM]":"277.0","Tissue RNA - stomach 1 [nTPM]":"467.3","Tissue RNA - testis [nTPM]":"96.7","Tissue RNA - thalamus [nTPM]":"480.4","Tissue RNA - thymus [nTPM]":"206.6","Tissue RNA - thyroid gland [nTPM]":"342.9","Tissue RNA - tongue [nTPM]":"1005.3","Tissue RNA - tonsil [nTPM]":"175.8","Tissue RNA - urinary bladder [nTPM]":"307.1","Tissue RNA - vagina [nTPM]":"331.2","Tissue RNA - white matter [nTPM]":"427.9","Cell RNA - A-431 [nTPM]":"613.9","Cell RNA - A549 [nTPM]":"803.9","Cell RNA - AF22 [nTPM]":"505.6","Cell RNA - AN3-CA [nTPM]":"505.2","Cell RNA - ASC diff [nTPM]":"213.8","Cell RNA - ASC TERT1 [nTPM]":"260.8","Cell RNA - BEWO [nTPM]":"365.3","Cell RNA - BJ [nTPM]":"317.0","Cell RNA - BJ hTERT+ [nTPM]":"355.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"621.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"480.1","Cell RNA - CACO-2 [nTPM]":"543.1","Cell RNA - CAPAN-2 [nTPM]":"489.1","Cell RNA - Daudi [nTPM]":"290.1","Cell RNA - EFO-21 [nTPM]":"680.8","Cell RNA - fHDF\/TERT166 [nTPM]":"447.1","Cell RNA - GAMG [nTPM]":"581.6","Cell RNA - HaCaT [nTPM]":"597.7","Cell RNA - HAP1 [nTPM]":"395.7","Cell RNA - HBEC3-KT [nTPM]":"550.9","Cell RNA - HBF TERT88 [nTPM]":"212.5","Cell RNA - HDLM-2 [nTPM]":"427.6","Cell RNA - HEK 293 [nTPM]":"687.8","Cell RNA - HEL [nTPM]":"423.2","Cell RNA - HeLa [nTPM]":"621.8","Cell RNA - Hep G2 [nTPM]":"650.3","Cell RNA - HHSteC [nTPM]":"341.4","Cell RNA - HL-60 [nTPM]":"431.0","Cell RNA - HMC-1 [nTPM]":"527.7","Cell RNA - HSkMC [nTPM]":"336.7","Cell RNA - hTCEpi [nTPM]":"412.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"497.3","Cell RNA - hTERT-HME1 [nTPM]":"398.6","Cell RNA - hTERT-RPE1 [nTPM]":"274.1","Cell RNA - HUVEC TERT2 [nTPM]":"391.9","Cell RNA - JURKAT [nTPM]":"676.2","Cell RNA - K-562 [nTPM]":"503.9","Cell RNA - Karpas-707 [nTPM]":"613.3","Cell RNA - LHCN-M2 [nTPM]":"397.7","Cell RNA - MCF7 [nTPM]":"1600.5","Cell RNA - MOLT-4 [nTPM]":"613.8","Cell RNA - NB-4 [nTPM]":"1461.1","Cell RNA - NTERA-2 [nTPM]":"460.7","Cell RNA - OE19 [nTPM]":"726.4","Cell RNA - PC-3 [nTPM]":"1401.4","Cell RNA - REH [nTPM]":"473.9","Cell RNA - RH-30 [nTPM]":"406.3","Cell RNA - RPMI-8226 [nTPM]":"1234.3","Cell RNA - RPTEC TERT1 [nTPM]":"512.9","Cell RNA - RT4 [nTPM]":"512.7","Cell RNA - SCLC-21H [nTPM]":"457.8","Cell RNA - SH-SY5Y [nTPM]":"645.0","Cell RNA - SiHa [nTPM]":"377.1","Cell RNA - SK-BR-3 [nTPM]":"541.2","Cell RNA - SK-MEL-30 [nTPM]":"816.1","Cell RNA - SuSa [nTPM]":"215.0","Cell RNA - T-47d [nTPM]":"796.1","Cell RNA - THP-1 [nTPM]":"459.8","Cell RNA - TIME [nTPM]":"240.7","Cell RNA - U-138 MG [nTPM]":"356.1","Cell RNA - U-2 OS [nTPM]":"481.0","Cell RNA - U-2197 [nTPM]":"769.2","Cell RNA - U-251 MG [nTPM]":"374.2","Cell RNA - U-266\/70 [nTPM]":"760.8","Cell RNA - U-266\/84 [nTPM]":"662.4","Cell RNA - U-698 [nTPM]":"461.7","Cell RNA - U-87 MG [nTPM]":"462.0","Cell RNA - U-937 [nTPM]":"420.9","Cell RNA - WM-115 [nTPM]":"436.9","Blood RNA - basophil [nTPM]":"764.9","Blood RNA - classical monocyte [nTPM]":"743.9","Blood RNA - eosinophil [nTPM]":"692.9","Blood RNA - gdT-cell [nTPM]":"407.0","Blood RNA - intermediate monocyte [nTPM]":"848.8","Blood RNA - MAIT T-cell [nTPM]":"301.5","Blood RNA - memory B-cell [nTPM]":"398.5","Blood RNA - memory CD4 T-cell [nTPM]":"441.6","Blood RNA - memory CD8 T-cell [nTPM]":"403.5","Blood RNA - myeloid DC [nTPM]":"867.0","Blood RNA - naive B-cell [nTPM]":"347.3","Blood RNA - naive CD4 T-cell [nTPM]":"337.1","Blood RNA - naive CD8 T-cell [nTPM]":"369.6","Blood RNA - neutrophil [nTPM]":"530.6","Blood RNA - NK-cell [nTPM]":"418.3","Blood RNA - non-classical monocyte [nTPM]":"794.1","Blood RNA - plasmacytoid DC [nTPM]":"851.2","Blood RNA - T-reg [nTPM]":"589.5","Blood RNA - total PBMC [nTPM]":"723.9","Brain RNA - amygdala [nTPM]":"421.6","Brain RNA - basal ganglia [nTPM]":"435.5","Brain RNA - cerebellum [nTPM]":"470.0","Brain RNA - cerebral cortex [nTPM]":"544.7","Brain RNA - hippocampal formation [nTPM]":"415.9","Brain RNA - hypothalamus [nTPM]":"469.2","Brain RNA - medulla oblongata [nTPM]":"421.5","Brain RNA - midbrain [nTPM]":"420.4","Brain RNA - pons [nTPM]":"414.7","Brain RNA - spinal cord [nTPM]":"427.7","Brain RNA - thalamus [nTPM]":"480.4","Brain RNA - white matter [nTPM]":"427.9","Single Cell Type RNA - Adipocytes [nTPM]":"236.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"224.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"259.8","Single Cell Type RNA - Astrocytes [nTPM]":"13.7","Single Cell Type RNA - B-cells [nTPM]":"255.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"294.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"392.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"640.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"385.3","Single Cell Type RNA - Bipolar cells [nTPM]":"196.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"394.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"458.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1263.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"424.7","Single Cell Type RNA - Club cells [nTPM]":"396.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"437.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"73.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"451.2","Single Cell Type RNA - dendritic cells [nTPM]":"305.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"1382.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"2341.9","Single Cell Type RNA - Ductal cells [nTPM]":"453.1","Single Cell Type RNA - Early spermatids [nTPM]":"9.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"271.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"217.2","Single Cell Type RNA - Endothelial cells [nTPM]":"215.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"721.6","Single Cell Type RNA - Erythroid cells [nTPM]":"272.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"483.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"559.6","Single Cell Type RNA - Fibroblasts [nTPM]":"246.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"395.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"305.1","Single Cell Type RNA - granulocytes [nTPM]":"224.5","Single Cell Type RNA - Granulosa cells [nTPM]":"209.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"227.4","Single Cell Type RNA - Hepatocytes [nTPM]":"811.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"927.5","Single Cell Type RNA - Horizontal cells [nTPM]":"107.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"16.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1011.7","Single Cell Type RNA - Ionocytes [nTPM]":"592.0","Single Cell Type RNA - Kupffer cells [nTPM]":"535.2","Single Cell Type RNA - Langerhans cells [nTPM]":"427.0","Single Cell Type RNA - Late spermatids [nTPM]":"25.6","Single Cell Type RNA - Leydig cells [nTPM]":"239.6","Single Cell Type RNA - Macrophages [nTPM]":"455.4","Single Cell Type RNA - Melanocytes [nTPM]":"627.9","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"508.9","Single Cell Type RNA - Muller glia cells [nTPM]":"429.3","Single Cell Type RNA - NK-cells [nTPM]":"416.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"562.9","Single Cell Type RNA - Paneth cells [nTPM]":"1103.8","Single Cell Type RNA - Peritubular cells [nTPM]":"221.2","Single Cell Type RNA - Plasma cells [nTPM]":"393.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"419.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1417.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1658.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"345.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"187.5","Single Cell Type RNA - Sertoli cells [nTPM]":"157.8","Single Cell Type RNA - Skeletal myocytes [nTPM]":"256.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"339.9","Single Cell Type RNA - Spermatocytes [nTPM]":"74.0","Single Cell Type RNA - Spermatogonia [nTPM]":"55.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"844.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"370.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"366.9","Single Cell Type RNA - T-cells [nTPM]":"290.4","Single Cell Type RNA - Theca cells [nTPM]":"203.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1088.7","Single Cell Type RNA - Urothelial cells [nTPM]":"593.4"},{"Gene":"CP","Gene synonym":[],"Ensembl":"ENSG00000047457","Gene description":"Ceruloplasmin","Uniprot":["P00450"],"Chromosome":"3","Position":"149162410-149221829","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins","Transporters"],"Biological process":["Copper transport","Ion transport","Transport"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"liver":"1871.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Club cells":"558.1","Glandular and luminal cells":"406.0","Hepatocytes":"1687.2","Muller glia cells":"720.5","Respiratory ciliated cells":"318.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"98.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"EFO-21":"318.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001834","CAB008591"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":160000000000,"Blood concentration - Conc. blood MS [pg\/L]":"440000000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB008591":"AB_1613734","HPA001834":"AB_1078502"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.14e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Tissue RNA - adipose tissue [nTPM]":"13.0","Tissue RNA - adrenal gland [nTPM]":"2.3","Tissue RNA - amygdala [nTPM]":"17.9","Tissue RNA - appendix [nTPM]":"2.2","Tissue RNA - basal ganglia [nTPM]":"18.1","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"20.8","Tissue RNA - cerebellum [nTPM]":"18.7","Tissue RNA - cerebral cortex [nTPM]":"29.8","Tissue RNA - cervix [nTPM]":"70.2","Tissue RNA - choroid plexus [nTPM]":"129.2","Tissue RNA - colon [nTPM]":"13.0","Tissue RNA - duodenum [nTPM]":"9.8","Tissue RNA - endometrium 1 [nTPM]":"14.8","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"5.6","Tissue RNA - fallopian tube [nTPM]":"8.3","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"39.2","Tissue RNA - hippocampal formation [nTPM]":"17.5","Tissue RNA - hypothalamus [nTPM]":"33.0","Tissue RNA - kidney [nTPM]":"9.5","Tissue RNA - liver [nTPM]":"1871.4","Tissue RNA - lung [nTPM]":"13.4","Tissue RNA - lymph node [nTPM]":"18.9","Tissue RNA - medulla oblongata [nTPM]":"28.1","Tissue RNA - midbrain [nTPM]":"20.3","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"6.5","Tissue RNA - parathyroid gland [nTPM]":"3.9","Tissue RNA - pituitary gland [nTPM]":"28.6","Tissue RNA - placenta [nTPM]":"3.4","Tissue RNA - pons [nTPM]":"24.9","Tissue RNA - prostate [nTPM]":"7.9","Tissue RNA - rectum [nTPM]":"16.4","Tissue RNA - retina [nTPM]":"246.5","Tissue RNA - salivary gland [nTPM]":"39.9","Tissue RNA - seminal vesicle [nTPM]":"0.9","Tissue RNA - skeletal muscle [nTPM]":"2.6","Tissue RNA - skin 1 [nTPM]":"13.0","Tissue RNA - small intestine [nTPM]":"20.8","Tissue RNA - smooth muscle [nTPM]":"2.4","Tissue RNA - spinal cord [nTPM]":"19.2","Tissue RNA - spleen [nTPM]":"23.1","Tissue RNA - stomach 1 [nTPM]":"3.0","Tissue RNA - testis [nTPM]":"1.5","Tissue RNA - thalamus [nTPM]":"20.1","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"16.1","Tissue RNA - tongue [nTPM]":"8.3","Tissue RNA - tonsil [nTPM]":"20.0","Tissue RNA - urinary bladder [nTPM]":"23.9","Tissue RNA - vagina [nTPM]":"2.3","Tissue RNA - white matter [nTPM]":"29.0","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"18.8","Cell RNA - AF22 [nTPM]":"15.6","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"3.3","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"318.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"29.4","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"32.7","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"2.5","Cell RNA - OE19 [nTPM]":"5.4","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"6.7","Cell RNA - RT4 [nTPM]":"16.2","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"1.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"1.7","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.9","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"17.9","Brain RNA - basal ganglia [nTPM]":"18.1","Brain RNA - cerebellum [nTPM]":"18.7","Brain RNA - cerebral cortex [nTPM]":"29.8","Brain RNA - hippocampal formation [nTPM]":"17.5","Brain RNA - hypothalamus [nTPM]":"33.0","Brain RNA - medulla oblongata [nTPM]":"28.1","Brain RNA - midbrain [nTPM]":"20.3","Brain RNA - pons [nTPM]":"24.9","Brain RNA - spinal cord [nTPM]":"19.2","Brain RNA - thalamus [nTPM]":"20.1","Brain RNA - white matter [nTPM]":"29.0","Single Cell Type RNA - Adipocytes [nTPM]":"2.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"76.6","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"10.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"28.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"6.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"65.8","Single Cell Type RNA - Club cells [nTPM]":"558.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"83.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"190.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"51.0","Single Cell Type RNA - Endothelial cells [nTPM]":"12.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"34.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"16.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"406.0","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"34.6","Single Cell Type RNA - Hepatocytes [nTPM]":"1687.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"44.6","Single Cell Type RNA - Langerhans cells [nTPM]":"6.9","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"4.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"1.6","Single Cell Type RNA - Muller glia cells [nTPM]":"720.5","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"69.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"318.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"4.9","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"79.0"},{"Gene":"CPA6","Gene synonym":["CPAH"],"Ensembl":"ENSG00000165078","Gene description":"Carboxypeptidase A6","Uniprot":["Q8N4T0"],"Chromosome":"8","Position":"67422038-67746378","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Carboxypeptidase","Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"2.3","prostate":"2.7","retina":"2.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"31.7","Early spermatids":"21.7","Microglial cells":"12.2","Muller glia cells":"22.5","Pancreatic endocrine cells":"21.5","Paneth cells":"12.8","Prostatic glandular cells":"11.3","Urothelial cells":"36.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"2.5","EFO-21":"1.5","Hep G2":"3.4","OE19":"1.5"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"9","RNA mouse brain regional specific nTPM":{"olfactory bulb":"12.6"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.61e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.6","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"2.7","Tissue RNA - rectum [nTPM]":"2.3","Tissue RNA - retina [nTPM]":"2.2","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.8","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"1.2","Tissue RNA - vagina [nTPM]":"1.1","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.9","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"2.5","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"3.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"1.5","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.5","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"31.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"21.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"22.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.5","Single Cell Type RNA - Paneth cells [nTPM]":"12.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.7","Single Cell Type RNA - Urothelial cells [nTPM]":"36.6"},{"Gene":"CPN1","Gene synonym":[],"Ensembl":"ENSG00000120054","Gene description":"Carboxypeptidase N subunit 1","Uniprot":["P15169"],"Chromosome":"10","Position":"100042193-100081869","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Carboxypeptidase","Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"54","RNA tissue specific nTPM":{"liver":"81.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hepatocytes":"37.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"liver cancer":"26.6","melanoma":"7.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"17","RNA cell line specific nTPM":{"SK-MEL-30":"141.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"13000000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"81.6","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"1.5","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"1.5","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"8.5","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"7.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"141.8","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"3.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"37.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"7.6","Single Cell Type RNA - Spermatogonia [nTPM]":"4.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CPOX","Gene synonym":["CPO","CPX","HCP"],"Ensembl":"ENSG00000080819","Gene description":"Coproporphyrinogen oxidase","Uniprot":["P36551"],"Chromosome":"3","Position":"98579446-98593648","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Heme biosynthesis","Porphyrin biosynthesis"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Hereditary hemolytic anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"352.8","Extravillous trophoblasts":"75.9","Oligodendrocytes":"99.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"166.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015736","HPA054448"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000","Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA015736":"AB_1847194","HPA054448":"AB_2682490"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.04e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Tissue RNA - adipose tissue [nTPM]":"8.1","Tissue RNA - adrenal gland [nTPM]":"10.0","Tissue RNA - amygdala [nTPM]":"19.7","Tissue RNA - appendix [nTPM]":"11.4","Tissue RNA - basal ganglia [nTPM]":"28.2","Tissue RNA - bone marrow [nTPM]":"44.1","Tissue RNA - breast [nTPM]":"7.2","Tissue RNA - cerebellum [nTPM]":"24.0","Tissue RNA - cerebral cortex [nTPM]":"31.7","Tissue RNA - cervix [nTPM]":"9.1","Tissue RNA - choroid plexus [nTPM]":"13.5","Tissue RNA - colon [nTPM]":"10.0","Tissue RNA - duodenum [nTPM]":"21.2","Tissue RNA - endometrium 1 [nTPM]":"10.1","Tissue RNA - epididymis [nTPM]":"7.2","Tissue RNA - esophagus [nTPM]":"16.1","Tissue RNA - fallopian tube [nTPM]":"7.4","Tissue RNA - gallbladder [nTPM]":"8.1","Tissue RNA - heart muscle [nTPM]":"8.6","Tissue RNA - hippocampal formation [nTPM]":"19.5","Tissue RNA - hypothalamus [nTPM]":"22.4","Tissue RNA - kidney [nTPM]":"6.5","Tissue RNA - liver [nTPM]":"35.3","Tissue RNA - lung [nTPM]":"7.5","Tissue RNA - lymph node [nTPM]":"12.3","Tissue RNA - medulla oblongata [nTPM]":"30.8","Tissue RNA - midbrain [nTPM]":"24.9","Tissue RNA - ovary [nTPM]":"10.7","Tissue RNA - pancreas [nTPM]":"7.2","Tissue RNA - parathyroid gland [nTPM]":"9.5","Tissue RNA - pituitary gland [nTPM]":"5.4","Tissue RNA - placenta [nTPM]":"18.0","Tissue RNA - pons [nTPM]":"29.8","Tissue RNA - prostate [nTPM]":"8.4","Tissue RNA - rectum [nTPM]":"12.0","Tissue RNA - retina [nTPM]":"4.5","Tissue RNA - salivary gland [nTPM]":"7.6","Tissue RNA - seminal vesicle [nTPM]":"7.9","Tissue RNA - skeletal muscle [nTPM]":"11.2","Tissue RNA - skin 1 [nTPM]":"13.1","Tissue RNA - small intestine [nTPM]":"15.2","Tissue RNA - smooth muscle [nTPM]":"9.0","Tissue RNA - spinal cord [nTPM]":"24.5","Tissue RNA - spleen [nTPM]":"9.5","Tissue RNA - stomach 1 [nTPM]":"9.4","Tissue RNA - testis [nTPM]":"4.7","Tissue RNA - thalamus [nTPM]":"25.1","Tissue RNA - thymus [nTPM]":"12.8","Tissue RNA - thyroid gland [nTPM]":"7.1","Tissue RNA - tongue [nTPM]":"9.8","Tissue RNA - tonsil [nTPM]":"12.3","Tissue RNA - urinary bladder [nTPM]":"8.1","Tissue RNA - vagina [nTPM]":"10.9","Tissue RNA - white matter [nTPM]":"41.8","Cell RNA - A-431 [nTPM]":"47.9","Cell RNA - A549 [nTPM]":"22.9","Cell RNA - AF22 [nTPM]":"19.9","Cell RNA - AN3-CA [nTPM]":"35.4","Cell RNA - ASC diff [nTPM]":"36.5","Cell RNA - ASC TERT1 [nTPM]":"26.9","Cell RNA - BEWO [nTPM]":"56.6","Cell RNA - BJ [nTPM]":"30.0","Cell RNA - BJ hTERT+ [nTPM]":"21.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"30.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"34.7","Cell RNA - CACO-2 [nTPM]":"38.2","Cell RNA - CAPAN-2 [nTPM]":"14.7","Cell RNA - Daudi [nTPM]":"5.0","Cell RNA - EFO-21 [nTPM]":"33.1","Cell RNA - fHDF\/TERT166 [nTPM]":"16.2","Cell RNA - GAMG [nTPM]":"33.6","Cell RNA - HaCaT [nTPM]":"34.1","Cell RNA - HAP1 [nTPM]":"24.9","Cell RNA - HBEC3-KT [nTPM]":"32.8","Cell RNA - HBF TERT88 [nTPM]":"51.9","Cell RNA - HDLM-2 [nTPM]":"15.4","Cell RNA - HEK 293 [nTPM]":"21.6","Cell RNA - HEL [nTPM]":"166.4","Cell RNA - HeLa [nTPM]":"12.9","Cell RNA - Hep G2 [nTPM]":"49.9","Cell RNA - HHSteC [nTPM]":"18.5","Cell RNA - HL-60 [nTPM]":"35.7","Cell RNA - HMC-1 [nTPM]":"37.8","Cell RNA - HSkMC [nTPM]":"21.2","Cell RNA - hTCEpi [nTPM]":"27.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"29.0","Cell RNA - hTERT-HME1 [nTPM]":"12.0","Cell RNA - hTERT-RPE1 [nTPM]":"35.9","Cell RNA - HUVEC TERT2 [nTPM]":"29.6","Cell RNA - JURKAT [nTPM]":"20.2","Cell RNA - K-562 [nTPM]":"32.2","Cell RNA - Karpas-707 [nTPM]":"20.9","Cell RNA - LHCN-M2 [nTPM]":"29.1","Cell RNA - MCF7 [nTPM]":"14.8","Cell RNA - MOLT-4 [nTPM]":"36.2","Cell RNA - NB-4 [nTPM]":"30.4","Cell RNA - NTERA-2 [nTPM]":"23.4","Cell RNA - OE19 [nTPM]":"26.6","Cell RNA - PC-3 [nTPM]":"41.0","Cell RNA - REH [nTPM]":"25.4","Cell RNA - RH-30 [nTPM]":"45.0","Cell RNA - RPMI-8226 [nTPM]":"22.1","Cell RNA - RPTEC TERT1 [nTPM]":"26.2","Cell RNA - RT4 [nTPM]":"19.8","Cell RNA - SCLC-21H [nTPM]":"13.1","Cell RNA - SH-SY5Y [nTPM]":"13.0","Cell RNA - SiHa [nTPM]":"32.0","Cell RNA - SK-BR-3 [nTPM]":"10.9","Cell RNA - SK-MEL-30 [nTPM]":"96.2","Cell RNA - SuSa [nTPM]":"22.1","Cell RNA - T-47d [nTPM]":"16.7","Cell RNA - THP-1 [nTPM]":"22.5","Cell RNA - TIME [nTPM]":"24.9","Cell RNA - U-138 MG [nTPM]":"45.1","Cell RNA - U-2 OS [nTPM]":"44.0","Cell RNA - U-2197 [nTPM]":"26.1","Cell RNA - U-251 MG [nTPM]":"22.4","Cell RNA - U-266\/70 [nTPM]":"31.6","Cell RNA - U-266\/84 [nTPM]":"26.8","Cell RNA - U-698 [nTPM]":"26.7","Cell RNA - U-87 MG [nTPM]":"44.6","Cell RNA - U-937 [nTPM]":"38.3","Cell RNA - WM-115 [nTPM]":"33.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.8","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"19.7","Brain RNA - basal ganglia [nTPM]":"28.2","Brain RNA - cerebellum [nTPM]":"24.0","Brain RNA - cerebral cortex [nTPM]":"31.7","Brain RNA - hippocampal formation [nTPM]":"19.5","Brain RNA - hypothalamus [nTPM]":"22.4","Brain RNA - medulla oblongata [nTPM]":"30.8","Brain RNA - midbrain [nTPM]":"24.9","Brain RNA - pons [nTPM]":"29.8","Brain RNA - spinal cord [nTPM]":"24.5","Brain RNA - thalamus [nTPM]":"25.1","Brain RNA - white matter [nTPM]":"41.8","Single Cell Type RNA - Adipocytes [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.7","Single Cell Type RNA - Astrocytes [nTPM]":"9.1","Single Cell Type RNA - B-cells [nTPM]":"5.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"4.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"4.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.9","Single Cell Type RNA - dendritic cells [nTPM]":"6.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.6","Single Cell Type RNA - Endothelial cells [nTPM]":"7.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"352.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"75.9","Single Cell Type RNA - Fibroblasts [nTPM]":"9.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"7.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"36.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.1","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"11.3","Single Cell Type RNA - Langerhans cells [nTPM]":"10.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"7.5","Single Cell Type RNA - Macrophages [nTPM]":"11.4","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"12.7","Single Cell Type RNA - Muller glia cells [nTPM]":"5.8","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"99.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.2","Single Cell Type RNA - Paneth cells [nTPM]":"4.1","Single Cell Type RNA - Peritubular cells [nTPM]":"7.9","Single Cell Type RNA - Plasma cells [nTPM]":"10.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"6.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.7","Single Cell Type RNA - T-cells [nTPM]":"12.7","Single Cell Type RNA - Theca cells [nTPM]":"9.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.9","Single Cell Type RNA - Urothelial cells [nTPM]":"4.2"},{"Gene":"CPT1C","Gene synonym":["CATL1","CPT1P","CPTIC","FLJ23809"],"Ensembl":"ENSG00000169169","Gene description":"Carnitine palmitoyltransferase 1C","Uniprot":["Q8TCG5"],"Chromosome":"19","Position":"49690898-49713731","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"19.2","pituitary gland":"28.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"43.4","Excitatory neurons":"34.0","Horizontal cells":"32.0","Inhibitory neurons":"28.1","Late spermatids":"29.7","Oligodendrocyte precursor cells":"21.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"9.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"40.2","AN3-CA":"33.2","SCLC-21H":"27.4","SH-SY5Y":"70.1","U-87 MG":"29.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014529","HPA063621"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA014529":"AB_1847206","HPA063621":"AB_2732706"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.84e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-3"},"Tissue RNA - adipose tissue [nTPM]":"3.4","Tissue RNA - adrenal gland [nTPM]":"5.3","Tissue RNA - amygdala [nTPM]":"14.0","Tissue RNA - appendix [nTPM]":"1.6","Tissue RNA - basal ganglia [nTPM]":"14.8","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"2.1","Tissue RNA - cerebellum [nTPM]":"8.5","Tissue RNA - cerebral cortex [nTPM]":"19.1","Tissue RNA - cervix [nTPM]":"6.5","Tissue RNA - choroid plexus [nTPM]":"18.8","Tissue RNA - colon [nTPM]":"2.6","Tissue RNA - duodenum [nTPM]":"1.3","Tissue RNA - endometrium 1 [nTPM]":"8.1","Tissue RNA - epididymis [nTPM]":"2.3","Tissue RNA - esophagus [nTPM]":"1.0","Tissue RNA - fallopian tube [nTPM]":"4.9","Tissue RNA - gallbladder [nTPM]":"4.4","Tissue RNA - heart muscle [nTPM]":"3.8","Tissue RNA - hippocampal formation [nTPM]":"19.2","Tissue RNA - hypothalamus [nTPM]":"15.6","Tissue RNA - kidney [nTPM]":"1.7","Tissue RNA - liver [nTPM]":"0.8","Tissue RNA - lung [nTPM]":"2.1","Tissue RNA - lymph node [nTPM]":"1.3","Tissue RNA - medulla oblongata [nTPM]":"10.1","Tissue RNA - midbrain [nTPM]":"9.2","Tissue RNA - ovary [nTPM]":"5.1","Tissue RNA - pancreas [nTPM]":"1.4","Tissue RNA - parathyroid gland [nTPM]":"1.4","Tissue RNA - pituitary gland [nTPM]":"28.4","Tissue RNA - placenta [nTPM]":"0.7","Tissue RNA - pons [nTPM]":"10.3","Tissue RNA - prostate [nTPM]":"3.4","Tissue RNA - rectum [nTPM]":"0.6","Tissue RNA - retina [nTPM]":"12.4","Tissue RNA - salivary gland [nTPM]":"1.0","Tissue RNA - seminal vesicle [nTPM]":"2.5","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"1.0","Tissue RNA - small intestine [nTPM]":"1.8","Tissue RNA - smooth muscle [nTPM]":"4.6","Tissue RNA - spinal cord [nTPM]":"4.9","Tissue RNA - spleen [nTPM]":"4.9","Tissue RNA - stomach 1 [nTPM]":"1.5","Tissue RNA - testis [nTPM]":"3.5","Tissue RNA - thalamus [nTPM]":"12.9","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"2.4","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.6","Tissue RNA - urinary bladder [nTPM]":"2.7","Tissue RNA - vagina [nTPM]":"3.7","Tissue RNA - white matter [nTPM]":"14.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"40.2","Cell RNA - AN3-CA [nTPM]":"33.2","Cell RNA - ASC diff [nTPM]":"14.0","Cell RNA - ASC TERT1 [nTPM]":"11.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"12.6","Cell RNA - BJ hTERT+ [nTPM]":"25.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"22.4","Cell RNA - CACO-2 [nTPM]":"0.7","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.8","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"12.7","Cell RNA - GAMG [nTPM]":"2.0","Cell RNA - HaCaT [nTPM]":"3.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"8.5","Cell RNA - HDLM-2 [nTPM]":"0.6","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"22.7","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"12.7","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.3","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"4.3","Cell RNA - HUVEC TERT2 [nTPM]":"22.2","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.9","Cell RNA - MCF7 [nTPM]":"0.7","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.8","Cell RNA - OE19 [nTPM]":"2.7","Cell RNA - PC-3 [nTPM]":"8.8","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.9","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"27.4","Cell RNA - SH-SY5Y [nTPM]":"70.1","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.6","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"18.3","Cell RNA - U-138 MG [nTPM]":"1.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"7.7","Cell RNA - U-251 MG [nTPM]":"6.7","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"3.2","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"29.5","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"14.0","Brain RNA - basal ganglia [nTPM]":"14.8","Brain RNA - cerebellum [nTPM]":"8.5","Brain RNA - cerebral cortex [nTPM]":"19.1","Brain RNA - hippocampal formation [nTPM]":"19.2","Brain RNA - hypothalamus [nTPM]":"15.6","Brain RNA - medulla oblongata [nTPM]":"10.1","Brain RNA - midbrain [nTPM]":"9.2","Brain RNA - pons [nTPM]":"10.3","Brain RNA - spinal cord [nTPM]":"4.9","Brain RNA - thalamus [nTPM]":"12.9","Brain RNA - white matter [nTPM]":"14.4","Single Cell Type RNA - Adipocytes [nTPM]":"3.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"7.5","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"43.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"8.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.1","Single Cell Type RNA - Endothelial cells [nTPM]":"7.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"34.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.4","Single Cell Type RNA - Fibroblasts [nTPM]":"6.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"32.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"28.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.9","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"29.7","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"18.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"21.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"13.2","Single Cell Type RNA - Plasma cells [nTPM]":"1.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.3","Single Cell Type RNA - Spermatocytes [nTPM]":"3.1","Single Cell Type RNA - Spermatogonia [nTPM]":"7.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - T-cells [nTPM]":"0.7","Single Cell Type RNA - Theca cells [nTPM]":"4.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"1.6"},{"Gene":"CRAT","Gene synonym":["CAT1"],"Ensembl":"ENSG00000095321","Gene description":"Carnitine O-acetyltransferase","Uniprot":["P43155"],"Chromosome":"9","Position":"129094142-129111189","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Fatty acid metabolism","Lipid metabolism","Transport"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"227.5","tongue":"201.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"181.2","Late spermatids":"521.8","Proximal enterocytes":"136.4","Spermatocytes":"123.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019230","HPA020260","HPA022815"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"8100","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA019230":"AB_1847212","HPA020260":"AB_1847210","HPA022815":"AB_2732427"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.36e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-2"},"Tissue RNA - adipose tissue [nTPM]":"36.1","Tissue RNA - adrenal gland [nTPM]":"51.3","Tissue RNA - amygdala [nTPM]":"26.4","Tissue RNA - appendix [nTPM]":"5.4","Tissue RNA - basal ganglia [nTPM]":"26.6","Tissue RNA - bone marrow [nTPM]":"9.0","Tissue RNA - breast [nTPM]":"29.2","Tissue RNA - cerebellum [nTPM]":"27.0","Tissue RNA - cerebral cortex [nTPM]":"33.8","Tissue RNA - cervix [nTPM]":"31.7","Tissue RNA - choroid plexus [nTPM]":"27.5","Tissue RNA - colon [nTPM]":"36.1","Tissue RNA - duodenum [nTPM]":"33.0","Tissue RNA - endometrium 1 [nTPM]":"24.8","Tissue RNA - epididymis [nTPM]":"4.0","Tissue RNA - esophagus [nTPM]":"37.3","Tissue RNA - fallopian tube [nTPM]":"23.1","Tissue RNA - gallbladder [nTPM]":"6.6","Tissue RNA - heart muscle [nTPM]":"68.2","Tissue RNA - hippocampal formation [nTPM]":"25.1","Tissue RNA - hypothalamus [nTPM]":"27.8","Tissue RNA - kidney [nTPM]":"46.9","Tissue RNA - liver [nTPM]":"151.2","Tissue RNA - lung [nTPM]":"15.2","Tissue RNA - lymph node [nTPM]":"3.2","Tissue RNA - medulla oblongata [nTPM]":"28.8","Tissue RNA - midbrain [nTPM]":"28.2","Tissue RNA - ovary [nTPM]":"23.0","Tissue RNA - pancreas [nTPM]":"107.1","Tissue RNA - parathyroid gland [nTPM]":"26.3","Tissue RNA - pituitary gland [nTPM]":"12.3","Tissue RNA - placenta [nTPM]":"6.6","Tissue RNA - pons [nTPM]":"30.6","Tissue RNA - prostate [nTPM]":"42.2","Tissue RNA - rectum [nTPM]":"4.2","Tissue RNA - retina [nTPM]":"1.7","Tissue RNA - salivary gland [nTPM]":"32.8","Tissue RNA - seminal vesicle [nTPM]":"8.9","Tissue RNA - skeletal muscle [nTPM]":"227.5","Tissue RNA - skin 1 [nTPM]":"29.6","Tissue RNA - small intestine [nTPM]":"37.2","Tissue RNA - smooth muscle [nTPM]":"6.8","Tissue RNA - spinal cord [nTPM]":"26.7","Tissue RNA - spleen [nTPM]":"15.2","Tissue RNA - stomach 1 [nTPM]":"34.0","Tissue RNA - testis [nTPM]":"146.4","Tissue RNA - thalamus [nTPM]":"30.2","Tissue RNA - thymus [nTPM]":"3.1","Tissue RNA - thyroid gland [nTPM]":"21.5","Tissue RNA - tongue [nTPM]":"201.3","Tissue RNA - tonsil [nTPM]":"1.6","Tissue RNA - urinary bladder [nTPM]":"31.3","Tissue RNA - vagina [nTPM]":"27.5","Tissue RNA - white matter [nTPM]":"24.4","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"39.3","Cell RNA - AF22 [nTPM]":"10.7","Cell RNA - AN3-CA [nTPM]":"21.3","Cell RNA - ASC diff [nTPM]":"13.4","Cell RNA - ASC TERT1 [nTPM]":"25.9","Cell RNA - BEWO [nTPM]":"17.0","Cell RNA - BJ [nTPM]":"15.0","Cell RNA - BJ hTERT+ [nTPM]":"16.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.0","Cell RNA - CACO-2 [nTPM]":"7.8","Cell RNA - CAPAN-2 [nTPM]":"14.0","Cell RNA - Daudi [nTPM]":"1.5","Cell RNA - EFO-21 [nTPM]":"9.2","Cell RNA - fHDF\/TERT166 [nTPM]":"25.9","Cell RNA - GAMG [nTPM]":"23.2","Cell RNA - HaCaT [nTPM]":"6.7","Cell RNA - HAP1 [nTPM]":"2.2","Cell RNA - HBEC3-KT [nTPM]":"4.9","Cell RNA - HBF TERT88 [nTPM]":"7.2","Cell RNA - HDLM-2 [nTPM]":"23.6","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"7.3","Cell RNA - HeLa [nTPM]":"19.1","Cell RNA - Hep G2 [nTPM]":"30.4","Cell RNA - HHSteC [nTPM]":"34.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"26.1","Cell RNA - HSkMC [nTPM]":"26.3","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.7","Cell RNA - hTERT-HME1 [nTPM]":"0.9","Cell RNA - hTERT-RPE1 [nTPM]":"15.8","Cell RNA - HUVEC TERT2 [nTPM]":"26.2","Cell RNA - JURKAT [nTPM]":"7.2","Cell RNA - K-562 [nTPM]":"3.6","Cell RNA - Karpas-707 [nTPM]":"5.7","Cell RNA - LHCN-M2 [nTPM]":"20.0","Cell RNA - MCF7 [nTPM]":"9.1","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"15.9","Cell RNA - NTERA-2 [nTPM]":"2.8","Cell RNA - OE19 [nTPM]":"32.0","Cell RNA - PC-3 [nTPM]":"18.0","Cell RNA - REH [nTPM]":"16.8","Cell RNA - RH-30 [nTPM]":"21.8","Cell RNA - RPMI-8226 [nTPM]":"12.2","Cell RNA - RPTEC TERT1 [nTPM]":"18.0","Cell RNA - RT4 [nTPM]":"0.6","Cell RNA - SCLC-21H [nTPM]":"4.2","Cell RNA - SH-SY5Y [nTPM]":"12.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"7.1","Cell RNA - SK-MEL-30 [nTPM]":"4.8","Cell RNA - SuSa [nTPM]":"3.4","Cell RNA - T-47d [nTPM]":"49.7","Cell RNA - THP-1 [nTPM]":"5.5","Cell RNA - TIME [nTPM]":"22.6","Cell RNA - U-138 MG [nTPM]":"23.0","Cell RNA - U-2 OS [nTPM]":"1.6","Cell RNA - U-2197 [nTPM]":"32.1","Cell RNA - U-251 MG [nTPM]":"15.4","Cell RNA - U-266\/70 [nTPM]":"25.5","Cell RNA - U-266\/84 [nTPM]":"22.6","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"28.8","Cell RNA - U-937 [nTPM]":"4.2","Cell RNA - WM-115 [nTPM]":"16.8","Blood RNA - basophil [nTPM]":"1.6","Blood RNA - classical monocyte [nTPM]":"8.4","Blood RNA - eosinophil [nTPM]":"3.5","Blood RNA - gdT-cell [nTPM]":"3.2","Blood RNA - intermediate monocyte [nTPM]":"5.5","Blood RNA - MAIT T-cell [nTPM]":"6.7","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"4.4","Blood RNA - memory CD8 T-cell [nTPM]":"4.3","Blood RNA - myeloid DC [nTPM]":"8.6","Blood RNA - naive B-cell [nTPM]":"1.3","Blood RNA - naive CD4 T-cell [nTPM]":"2.6","Blood RNA - naive CD8 T-cell [nTPM]":"3.1","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"4.4","Blood RNA - non-classical monocyte [nTPM]":"5.6","Blood RNA - plasmacytoid DC [nTPM]":"3.9","Blood RNA - T-reg [nTPM]":"4.5","Blood RNA - total PBMC [nTPM]":"6.1","Brain RNA - amygdala [nTPM]":"26.4","Brain RNA - basal ganglia [nTPM]":"26.6","Brain RNA - cerebellum [nTPM]":"27.0","Brain RNA - cerebral cortex [nTPM]":"33.8","Brain RNA - hippocampal formation [nTPM]":"25.1","Brain RNA - hypothalamus [nTPM]":"27.8","Brain RNA - medulla oblongata [nTPM]":"28.8","Brain RNA - midbrain [nTPM]":"28.2","Brain RNA - pons [nTPM]":"30.6","Brain RNA - spinal cord [nTPM]":"26.7","Brain RNA - thalamus [nTPM]":"30.2","Brain RNA - white matter [nTPM]":"24.4","Single Cell Type RNA - Adipocytes [nTPM]":"10.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.7","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"4.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"57.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"8.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"45.9","Single Cell Type RNA - dendritic cells [nTPM]":"6.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"64.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"22.6","Single Cell Type RNA - Early spermatids [nTPM]":"181.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.7","Single Cell Type RNA - Endothelial cells [nTPM]":"12.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.5","Single Cell Type RNA - Erythroid cells [nTPM]":"17.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"22.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"55.6","Single Cell Type RNA - Fibroblasts [nTPM]":"19.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.9","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"12.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"65.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.7","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.6","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"13.9","Single Cell Type RNA - Langerhans cells [nTPM]":"10.5","Single Cell Type RNA - Late spermatids [nTPM]":"521.8","Single Cell Type RNA - Leydig cells [nTPM]":"22.1","Single Cell Type RNA - Macrophages [nTPM]":"12.4","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"8.3","Single Cell Type RNA - Muller glia cells [nTPM]":"15.5","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.6","Single Cell Type RNA - Paneth cells [nTPM]":"47.6","Single Cell Type RNA - Peritubular cells [nTPM]":"24.5","Single Cell Type RNA - Plasma cells [nTPM]":"9.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"136.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"52.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.7","Single Cell Type RNA - Spermatocytes [nTPM]":"123.5","Single Cell Type RNA - Spermatogonia [nTPM]":"8.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"57.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"50.3","Single Cell Type RNA - T-cells [nTPM]":"7.6","Single Cell Type RNA - Theca cells [nTPM]":"20.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"29.3","Single Cell Type RNA - Urothelial cells [nTPM]":"13.8"},{"Gene":"CREBBP","Gene synonym":["CBP","KAT3A","RSTS","RTS"],"Ensembl":"ENSG00000005339","Gene description":"CREB binding protein","Uniprot":["Q92793"],"Chromosome":"16","Position":"3725054-3880713","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Biological rhythms","Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Activator","Acyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004212","HPA055861"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"CAB004212":"AB_626817","HPA055861":"AB_2682948"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.59e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.24e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-2"},"Tissue RNA - adipose tissue [nTPM]":"17.4","Tissue RNA - adrenal gland [nTPM]":"10.6","Tissue RNA - amygdala [nTPM]":"5.8","Tissue RNA - appendix [nTPM]":"17.1","Tissue RNA - basal ganglia [nTPM]":"5.2","Tissue RNA - bone marrow [nTPM]":"52.9","Tissue RNA - breast [nTPM]":"16.8","Tissue RNA - cerebellum [nTPM]":"25.4","Tissue RNA - cerebral cortex [nTPM]":"11.5","Tissue RNA - cervix [nTPM]":"20.9","Tissue RNA - choroid plexus [nTPM]":"3.7","Tissue RNA - colon [nTPM]":"18.8","Tissue RNA - duodenum [nTPM]":"12.5","Tissue RNA - endometrium 1 [nTPM]":"26.5","Tissue RNA - epididymis [nTPM]":"12.4","Tissue RNA - esophagus [nTPM]":"16.5","Tissue RNA - fallopian tube [nTPM]":"22.4","Tissue RNA - gallbladder [nTPM]":"16.6","Tissue RNA - heart muscle [nTPM]":"14.4","Tissue RNA - hippocampal formation [nTPM]":"5.9","Tissue RNA - hypothalamus [nTPM]":"3.1","Tissue RNA - kidney [nTPM]":"12.0","Tissue RNA - liver [nTPM]":"14.3","Tissue RNA - lung [nTPM]":"15.9","Tissue RNA - lymph node [nTPM]":"17.6","Tissue RNA - medulla oblongata [nTPM]":"8.9","Tissue RNA - midbrain [nTPM]":"6.8","Tissue RNA - ovary [nTPM]":"37.3","Tissue RNA - pancreas [nTPM]":"29.7","Tissue RNA - parathyroid gland [nTPM]":"18.5","Tissue RNA - pituitary gland [nTPM]":"11.3","Tissue RNA - placenta [nTPM]":"16.9","Tissue RNA - pons [nTPM]":"2.9","Tissue RNA - prostate [nTPM]":"16.1","Tissue RNA - rectum [nTPM]":"14.1","Tissue RNA - retina [nTPM]":"13.8","Tissue RNA - salivary gland [nTPM]":"17.2","Tissue RNA - seminal vesicle [nTPM]":"16.2","Tissue RNA - skeletal muscle [nTPM]":"29.6","Tissue RNA - skin 1 [nTPM]":"21.0","Tissue RNA - small intestine [nTPM]":"16.4","Tissue RNA - smooth muscle [nTPM]":"19.6","Tissue RNA - spinal cord [nTPM]":"0.4","Tissue RNA - spleen [nTPM]":"21.0","Tissue RNA - stomach 1 [nTPM]":"16.3","Tissue RNA - testis [nTPM]":"33.2","Tissue RNA - thalamus [nTPM]":"7.9","Tissue RNA - thymus [nTPM]":"29.1","Tissue RNA - thyroid gland [nTPM]":"23.3","Tissue RNA - tongue [nTPM]":"28.9","Tissue RNA - tonsil [nTPM]":"20.7","Tissue RNA - urinary bladder [nTPM]":"16.6","Tissue RNA - vagina [nTPM]":"16.5","Tissue RNA - white matter [nTPM]":"6.4","Cell RNA - A-431 [nTPM]":"12.3","Cell RNA - A549 [nTPM]":"31.0","Cell RNA - AF22 [nTPM]":"39.3","Cell RNA - AN3-CA [nTPM]":"17.4","Cell RNA - ASC diff [nTPM]":"23.5","Cell RNA - ASC TERT1 [nTPM]":"23.1","Cell RNA - BEWO [nTPM]":"20.4","Cell RNA - BJ [nTPM]":"17.4","Cell RNA - BJ hTERT+ [nTPM]":"28.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"29.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"28.2","Cell RNA - CACO-2 [nTPM]":"28.2","Cell RNA - CAPAN-2 [nTPM]":"22.4","Cell RNA - Daudi [nTPM]":"33.7","Cell RNA - EFO-21 [nTPM]":"20.1","Cell RNA - fHDF\/TERT166 [nTPM]":"33.3","Cell RNA - GAMG [nTPM]":"18.7","Cell RNA - HaCaT [nTPM]":"23.2","Cell RNA - HAP1 [nTPM]":"45.7","Cell RNA - HBEC3-KT [nTPM]":"14.2","Cell RNA - HBF TERT88 [nTPM]":"32.9","Cell RNA - HDLM-2 [nTPM]":"57.5","Cell RNA - HEK 293 [nTPM]":"18.5","Cell RNA - HEL [nTPM]":"26.6","Cell RNA - HeLa [nTPM]":"29.2","Cell RNA - Hep G2 [nTPM]":"17.9","Cell RNA - HHSteC [nTPM]":"26.0","Cell RNA - HL-60 [nTPM]":"26.9","Cell RNA - HMC-1 [nTPM]":"36.5","Cell RNA - HSkMC [nTPM]":"20.7","Cell RNA - hTCEpi [nTPM]":"14.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.5","Cell RNA - hTERT-HME1 [nTPM]":"38.9","Cell RNA - hTERT-RPE1 [nTPM]":"18.0","Cell RNA - HUVEC TERT2 [nTPM]":"22.3","Cell RNA - JURKAT [nTPM]":"17.0","Cell RNA - K-562 [nTPM]":"30.9","Cell RNA - Karpas-707 [nTPM]":"44.8","Cell RNA - LHCN-M2 [nTPM]":"16.0","Cell RNA - MCF7 [nTPM]":"42.0","Cell RNA - MOLT-4 [nTPM]":"17.9","Cell RNA - NB-4 [nTPM]":"13.0","Cell RNA - NTERA-2 [nTPM]":"32.3","Cell RNA - OE19 [nTPM]":"11.7","Cell RNA - PC-3 [nTPM]":"12.7","Cell RNA - REH [nTPM]":"83.4","Cell RNA - RH-30 [nTPM]":"31.1","Cell RNA - RPMI-8226 [nTPM]":"26.1","Cell RNA - RPTEC TERT1 [nTPM]":"11.2","Cell RNA - RT4 [nTPM]":"16.2","Cell RNA - SCLC-21H [nTPM]":"32.6","Cell RNA - SH-SY5Y [nTPM]":"21.5","Cell RNA - SiHa [nTPM]":"29.5","Cell RNA - SK-BR-3 [nTPM]":"28.7","Cell RNA - SK-MEL-30 [nTPM]":"16.8","Cell RNA - SuSa [nTPM]":"25.3","Cell RNA - T-47d [nTPM]":"25.6","Cell RNA - THP-1 [nTPM]":"25.9","Cell RNA - TIME [nTPM]":"34.7","Cell RNA - U-138 MG [nTPM]":"35.5","Cell RNA - U-2 OS [nTPM]":"35.2","Cell RNA - U-2197 [nTPM]":"18.4","Cell RNA - U-251 MG [nTPM]":"16.0","Cell RNA - U-266\/70 [nTPM]":"20.8","Cell RNA - U-266\/84 [nTPM]":"24.3","Cell RNA - U-698 [nTPM]":"63.7","Cell RNA - U-87 MG [nTPM]":"7.2","Cell RNA - U-937 [nTPM]":"15.8","Cell RNA - WM-115 [nTPM]":"25.6","Blood RNA - basophil [nTPM]":"1.9","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"0.9","Blood RNA - gdT-cell [nTPM]":"1.7","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"3.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"1.3","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.1","Blood RNA - neutrophil [nTPM]":"6.7","Blood RNA - NK-cell [nTPM]":"1.4","Blood RNA - non-classical monocyte [nTPM]":"2.9","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"5.8","Brain RNA - basal ganglia [nTPM]":"5.2","Brain RNA - cerebellum [nTPM]":"25.4","Brain RNA - cerebral cortex [nTPM]":"11.5","Brain RNA - hippocampal formation [nTPM]":"5.9","Brain RNA - hypothalamus [nTPM]":"3.1","Brain RNA - medulla oblongata [nTPM]":"8.9","Brain RNA - midbrain [nTPM]":"6.8","Brain RNA - pons [nTPM]":"2.9","Brain RNA - spinal cord [nTPM]":"0.4","Brain RNA - thalamus [nTPM]":"7.9","Brain RNA - white matter [nTPM]":"6.4","Single Cell Type RNA - Adipocytes [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"51.6","Single Cell Type RNA - Astrocytes [nTPM]":"91.1","Single Cell Type RNA - B-cells [nTPM]":"38.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"56.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"31.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"27.3","Single Cell Type RNA - Bipolar cells [nTPM]":"34.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"34.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"25.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"41.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"40.0","Single Cell Type RNA - Club cells [nTPM]":"28.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"17.4","Single Cell Type RNA - dendritic cells [nTPM]":"50.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"31.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"20.9","Single Cell Type RNA - Early spermatids [nTPM]":"43.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"37.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"56.4","Single Cell Type RNA - Endothelial cells [nTPM]":"35.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.0","Single Cell Type RNA - Erythroid cells [nTPM]":"33.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"88.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"20.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.3","Single Cell Type RNA - Fibroblasts [nTPM]":"39.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"63.5","Single Cell Type RNA - granulocytes [nTPM]":"30.4","Single Cell Type RNA - Granulosa cells [nTPM]":"53.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.5","Single Cell Type RNA - Hepatocytes [nTPM]":"29.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.9","Single Cell Type RNA - Horizontal cells [nTPM]":"28.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"89.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"25.3","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"44.0","Single Cell Type RNA - Langerhans cells [nTPM]":"42.8","Single Cell Type RNA - Late spermatids [nTPM]":"80.2","Single Cell Type RNA - Leydig cells [nTPM]":"56.5","Single Cell Type RNA - Macrophages [nTPM]":"49.0","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"87.1","Single Cell Type RNA - monocytes [nTPM]":"52.5","Single Cell Type RNA - Muller glia cells [nTPM]":"34.5","Single Cell Type RNA - NK-cells [nTPM]":"43.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"111.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"101.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"27.5","Single Cell Type RNA - Paneth cells [nTPM]":"19.5","Single Cell Type RNA - Peritubular cells [nTPM]":"51.1","Single Cell Type RNA - Plasma cells [nTPM]":"35.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"39.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"25.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.6","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"75.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"44.9","Single Cell Type RNA - Spermatocytes [nTPM]":"35.1","Single Cell Type RNA - Spermatogonia [nTPM]":"42.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"34.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"58.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"30.8","Single Cell Type RNA - T-cells [nTPM]":"44.2","Single Cell Type RNA - Theca cells [nTPM]":"36.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.6","Single Cell Type RNA - Urothelial cells [nTPM]":"44.2"},{"Gene":"CRELD1","Gene synonym":["AVSD2","CIRRIN"],"Ensembl":"ENSG00000163703","Gene description":"Cysteine rich with EGF like domains 1","Uniprot":["Q96HD1"],"Chromosome":"3","Position":"9933816-9945406","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Isomerase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"110.3","hTERT-RPE1":"77.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026964"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"19000000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA026964":"AB_10602210"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.07e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Tissue RNA - adipose tissue [nTPM]":"32.7","Tissue RNA - adrenal gland [nTPM]":"37.3","Tissue RNA - amygdala [nTPM]":"63.6","Tissue RNA - appendix [nTPM]":"11.4","Tissue RNA - basal ganglia [nTPM]":"63.5","Tissue RNA - bone marrow [nTPM]":"9.3","Tissue RNA - breast [nTPM]":"24.8","Tissue RNA - cerebellum [nTPM]":"69.1","Tissue RNA - cerebral cortex [nTPM]":"94.4","Tissue RNA - cervix [nTPM]":"27.7","Tissue RNA - choroid plexus [nTPM]":"59.1","Tissue RNA - colon [nTPM]":"57.5","Tissue RNA - duodenum [nTPM]":"14.0","Tissue RNA - endometrium 1 [nTPM]":"31.3","Tissue RNA - epididymis [nTPM]":"17.0","Tissue RNA - esophagus [nTPM]":"18.0","Tissue RNA - fallopian tube [nTPM]":"34.9","Tissue RNA - gallbladder [nTPM]":"16.5","Tissue RNA - heart muscle [nTPM]":"73.2","Tissue RNA - hippocampal formation [nTPM]":"63.9","Tissue RNA - hypothalamus [nTPM]":"65.7","Tissue RNA - kidney [nTPM]":"43.0","Tissue RNA - liver [nTPM]":"57.1","Tissue RNA - lung [nTPM]":"27.5","Tissue RNA - lymph node [nTPM]":"12.4","Tissue RNA - medulla oblongata [nTPM]":"64.7","Tissue RNA - midbrain [nTPM]":"63.0","Tissue RNA - ovary [nTPM]":"32.5","Tissue RNA - pancreas [nTPM]":"27.6","Tissue RNA - parathyroid gland [nTPM]":"22.7","Tissue RNA - pituitary gland [nTPM]":"70.9","Tissue RNA - placenta [nTPM]":"17.9","Tissue RNA - pons [nTPM]":"66.3","Tissue RNA - prostate [nTPM]":"47.6","Tissue RNA - rectum [nTPM]":"12.1","Tissue RNA - retina [nTPM]":"16.4","Tissue RNA - salivary gland [nTPM]":"26.3","Tissue RNA - seminal vesicle [nTPM]":"34.5","Tissue RNA - skeletal muscle [nTPM]":"48.9","Tissue RNA - skin 1 [nTPM]":"20.1","Tissue RNA - small intestine [nTPM]":"25.9","Tissue RNA - smooth muscle [nTPM]":"22.2","Tissue RNA - spinal cord [nTPM]":"58.6","Tissue RNA - spleen [nTPM]":"28.6","Tissue RNA - stomach 1 [nTPM]":"35.6","Tissue RNA - testis [nTPM]":"23.6","Tissue RNA - thalamus [nTPM]":"65.5","Tissue RNA - thymus [nTPM]":"10.5","Tissue RNA - thyroid gland [nTPM]":"67.6","Tissue RNA - tongue [nTPM]":"26.4","Tissue RNA - tonsil [nTPM]":"9.2","Tissue RNA - urinary bladder [nTPM]":"33.6","Tissue RNA - vagina [nTPM]":"24.4","Tissue RNA - white matter [nTPM]":"68.2","Cell RNA - A-431 [nTPM]":"6.4","Cell RNA - A549 [nTPM]":"8.1","Cell RNA - AF22 [nTPM]":"19.3","Cell RNA - AN3-CA [nTPM]":"8.8","Cell RNA - ASC diff [nTPM]":"30.1","Cell RNA - ASC TERT1 [nTPM]":"17.6","Cell RNA - BEWO [nTPM]":"110.3","Cell RNA - BJ [nTPM]":"26.7","Cell RNA - BJ hTERT+ [nTPM]":"8.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.7","Cell RNA - CACO-2 [nTPM]":"11.1","Cell RNA - CAPAN-2 [nTPM]":"20.7","Cell RNA - Daudi [nTPM]":"8.4","Cell RNA - EFO-21 [nTPM]":"57.6","Cell RNA - fHDF\/TERT166 [nTPM]":"17.7","Cell RNA - GAMG [nTPM]":"27.7","Cell RNA - HaCaT [nTPM]":"4.5","Cell RNA - HAP1 [nTPM]":"10.4","Cell RNA - HBEC3-KT [nTPM]":"17.6","Cell RNA - HBF TERT88 [nTPM]":"4.9","Cell RNA - HDLM-2 [nTPM]":"15.2","Cell RNA - HEK 293 [nTPM]":"9.2","Cell RNA - HEL [nTPM]":"7.3","Cell RNA - HeLa [nTPM]":"15.2","Cell RNA - Hep G2 [nTPM]":"28.2","Cell RNA - HHSteC [nTPM]":"68.7","Cell RNA - HL-60 [nTPM]":"3.3","Cell RNA - HMC-1 [nTPM]":"29.3","Cell RNA - HSkMC [nTPM]":"21.7","Cell RNA - hTCEpi [nTPM]":"32.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.2","Cell RNA - hTERT-HME1 [nTPM]":"13.6","Cell RNA - hTERT-RPE1 [nTPM]":"77.2","Cell RNA - HUVEC TERT2 [nTPM]":"28.8","Cell RNA - JURKAT [nTPM]":"11.1","Cell RNA - K-562 [nTPM]":"9.5","Cell RNA - Karpas-707 [nTPM]":"10.4","Cell RNA - LHCN-M2 [nTPM]":"6.1","Cell RNA - MCF7 [nTPM]":"15.5","Cell RNA - MOLT-4 [nTPM]":"3.6","Cell RNA - NB-4 [nTPM]":"19.3","Cell RNA - NTERA-2 [nTPM]":"5.7","Cell RNA - OE19 [nTPM]":"30.1","Cell RNA - PC-3 [nTPM]":"6.6","Cell RNA - REH [nTPM]":"4.8","Cell RNA - RH-30 [nTPM]":"3.1","Cell RNA - RPMI-8226 [nTPM]":"21.6","Cell RNA - RPTEC TERT1 [nTPM]":"25.9","Cell RNA - RT4 [nTPM]":"9.9","Cell RNA - SCLC-21H [nTPM]":"6.9","Cell RNA - SH-SY5Y [nTPM]":"26.7","Cell RNA - SiHa [nTPM]":"12.6","Cell RNA - SK-BR-3 [nTPM]":"10.3","Cell RNA - SK-MEL-30 [nTPM]":"24.3","Cell RNA - SuSa [nTPM]":"27.5","Cell RNA - T-47d [nTPM]":"27.9","Cell RNA - THP-1 [nTPM]":"17.0","Cell RNA - TIME [nTPM]":"21.7","Cell RNA - U-138 MG [nTPM]":"12.1","Cell RNA - U-2 OS [nTPM]":"19.5","Cell RNA - U-2197 [nTPM]":"16.2","Cell RNA - U-251 MG [nTPM]":"6.3","Cell RNA - U-266\/70 [nTPM]":"10.7","Cell RNA - U-266\/84 [nTPM]":"14.2","Cell RNA - U-698 [nTPM]":"15.2","Cell RNA - U-87 MG [nTPM]":"27.3","Cell RNA - U-937 [nTPM]":"7.8","Cell RNA - WM-115 [nTPM]":"13.0","Blood RNA - basophil [nTPM]":"12.3","Blood RNA - classical monocyte [nTPM]":"10.2","Blood RNA - eosinophil [nTPM]":"9.3","Blood RNA - gdT-cell [nTPM]":"11.9","Blood RNA - intermediate monocyte [nTPM]":"9.8","Blood RNA - MAIT T-cell [nTPM]":"12.2","Blood RNA - memory B-cell [nTPM]":"7.9","Blood RNA - memory CD4 T-cell [nTPM]":"8.9","Blood RNA - memory CD8 T-cell [nTPM]":"11.5","Blood RNA - myeloid DC [nTPM]":"6.9","Blood RNA - naive B-cell [nTPM]":"8.7","Blood RNA - naive CD4 T-cell [nTPM]":"11.3","Blood RNA - naive CD8 T-cell [nTPM]":"10.4","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"13.8","Blood RNA - non-classical monocyte [nTPM]":"12.9","Blood RNA - plasmacytoid DC [nTPM]":"12.3","Blood RNA - T-reg [nTPM]":"7.2","Blood RNA - total PBMC [nTPM]":"9.5","Brain RNA - amygdala [nTPM]":"63.6","Brain RNA - basal ganglia [nTPM]":"63.5","Brain RNA - cerebellum [nTPM]":"69.1","Brain RNA - cerebral cortex [nTPM]":"94.4","Brain RNA - hippocampal formation [nTPM]":"63.9","Brain RNA - hypothalamus [nTPM]":"65.7","Brain RNA - medulla oblongata [nTPM]":"64.7","Brain RNA - midbrain [nTPM]":"63.0","Brain RNA - pons [nTPM]":"66.3","Brain RNA - spinal cord [nTPM]":"58.6","Brain RNA - thalamus [nTPM]":"65.5","Brain RNA - white matter [nTPM]":"68.2","Single Cell Type RNA - Adipocytes [nTPM]":"24.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.5","Single Cell Type RNA - Astrocytes [nTPM]":"43.4","Single Cell Type RNA - B-cells [nTPM]":"14.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"26.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"48.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Bipolar cells [nTPM]":"21.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"41.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"31.5","Single Cell Type RNA - Club cells [nTPM]":"24.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.7","Single Cell Type RNA - dendritic cells [nTPM]":"15.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"19.6","Single Cell Type RNA - Early spermatids [nTPM]":"6.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.0","Single Cell Type RNA - Endothelial cells [nTPM]":"20.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"27.0","Single Cell Type RNA - Erythroid cells [nTPM]":"7.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"38.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.5","Single Cell Type RNA - Fibroblasts [nTPM]":"20.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.9","Single Cell Type RNA - granulocytes [nTPM]":"21.0","Single Cell Type RNA - Granulosa cells [nTPM]":"18.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.2","Single Cell Type RNA - Hepatocytes [nTPM]":"14.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.6","Single Cell Type RNA - Horizontal cells [nTPM]":"32.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.1","Single Cell Type RNA - Ionocytes [nTPM]":"38.7","Single Cell Type RNA - Kupffer cells [nTPM]":"8.8","Single Cell Type RNA - Langerhans cells [nTPM]":"9.0","Single Cell Type RNA - Late spermatids [nTPM]":"10.1","Single Cell Type RNA - Leydig cells [nTPM]":"32.0","Single Cell Type RNA - Macrophages [nTPM]":"10.0","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"13.9","Single Cell Type RNA - Muller glia cells [nTPM]":"18.3","Single Cell Type RNA - NK-cells [nTPM]":"27.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.7","Single Cell Type RNA - Paneth cells [nTPM]":"20.4","Single Cell Type RNA - Peritubular cells [nTPM]":"26.4","Single Cell Type RNA - Plasma cells [nTPM]":"15.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"31.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.8","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.1","Single Cell Type RNA - Spermatocytes [nTPM]":"68.0","Single Cell Type RNA - Spermatogonia [nTPM]":"26.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.2","Single Cell Type RNA - T-cells [nTPM]":"15.4","Single Cell Type RNA - Theca cells [nTPM]":"11.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.4","Single Cell Type RNA - Urothelial cells [nTPM]":"20.2"},{"Gene":"CRPPA","Gene synonym":["hCG_1745121","ISPD","Nip"],"Ensembl":"ENSG00000214960","Gene description":"CDP-L-ribitol pyrophosphorylase A","Uniprot":["A4D126"],"Chromosome":"7","Position":"16087525-16502504","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Nucleotidyltransferase","Transferase"],"Disease involvement":["Congenital muscular dystrophy","Disease variant","Dystroglycanopathy","Limb-girdle muscular dystrophy","Lissencephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"choroid plexus":"27.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cardiomyocytes":"8.0","Cytotrophoblasts":"3.5","Extravillous trophoblasts":"10.6","Syncytiotrophoblasts":"2.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"29","RNA blood cell specific nTPM":{"basophil":"13.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"29","RNA blood lineage specific nTPM":{"granulocytes":"13.8"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"9.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053554"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA053554":"AB_2682185"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.38e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.1","Tissue RNA - adrenal gland [nTPM]":"1.2","Tissue RNA - amygdala [nTPM]":"1.3","Tissue RNA - appendix [nTPM]":"0.8","Tissue RNA - basal ganglia [nTPM]":"1.8","Tissue RNA - bone marrow [nTPM]":"1.6","Tissue RNA - breast [nTPM]":"0.9","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"3.7","Tissue RNA - cervix [nTPM]":"1.3","Tissue RNA - choroid plexus [nTPM]":"27.0","Tissue RNA - colon [nTPM]":"1.0","Tissue RNA - duodenum [nTPM]":"0.6","Tissue RNA - endometrium 1 [nTPM]":"1.0","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"0.5","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"2.6","Tissue RNA - hippocampal formation [nTPM]":"3.8","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"2.9","Tissue RNA - liver [nTPM]":"4.1","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"1.4","Tissue RNA - medulla oblongata [nTPM]":"0.8","Tissue RNA - midbrain [nTPM]":"0.8","Tissue RNA - ovary [nTPM]":"0.7","Tissue RNA - pancreas [nTPM]":"1.5","Tissue RNA - parathyroid gland [nTPM]":"1.1","Tissue RNA - pituitary gland [nTPM]":"0.7","Tissue RNA - placenta [nTPM]":"1.0","Tissue RNA - pons [nTPM]":"0.8","Tissue RNA - prostate [nTPM]":"1.0","Tissue RNA - rectum [nTPM]":"1.2","Tissue RNA - retina [nTPM]":"1.2","Tissue RNA - salivary gland [nTPM]":"1.2","Tissue RNA - seminal vesicle [nTPM]":"0.8","Tissue RNA - skeletal muscle [nTPM]":"1.5","Tissue RNA - skin 1 [nTPM]":"1.2","Tissue RNA - small intestine [nTPM]":"0.6","Tissue RNA - smooth muscle [nTPM]":"1.2","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.9","Tissue RNA - stomach 1 [nTPM]":"3.5","Tissue RNA - testis [nTPM]":"2.2","Tissue RNA - thalamus [nTPM]":"3.2","Tissue RNA - thymus [nTPM]":"1.2","Tissue RNA - thyroid gland [nTPM]":"0.8","Tissue RNA - tongue [nTPM]":"1.3","Tissue RNA - tonsil [nTPM]":"1.4","Tissue RNA - urinary bladder [nTPM]":"1.1","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"2.0","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"2.2","Cell RNA - AF22 [nTPM]":"1.0","Cell RNA - AN3-CA [nTPM]":"1.6","Cell RNA - ASC diff [nTPM]":"1.0","Cell RNA - ASC TERT1 [nTPM]":"1.3","Cell RNA - BEWO [nTPM]":"6.8","Cell RNA - BJ [nTPM]":"1.5","Cell RNA - BJ hTERT+ [nTPM]":"1.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.3","Cell RNA - CACO-2 [nTPM]":"2.2","Cell RNA - CAPAN-2 [nTPM]":"1.9","Cell RNA - Daudi [nTPM]":"4.3","Cell RNA - EFO-21 [nTPM]":"3.2","Cell RNA - fHDF\/TERT166 [nTPM]":"2.7","Cell RNA - GAMG [nTPM]":"0.9","Cell RNA - HaCaT [nTPM]":"2.5","Cell RNA - HAP1 [nTPM]":"1.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"2.9","Cell RNA - HDLM-2 [nTPM]":"1.5","Cell RNA - HEK 293 [nTPM]":"0.9","Cell RNA - HEL [nTPM]":"9.6","Cell RNA - HeLa [nTPM]":"1.4","Cell RNA - Hep G2 [nTPM]":"0.7","Cell RNA - HHSteC [nTPM]":"1.5","Cell RNA - HL-60 [nTPM]":"1.9","Cell RNA - HMC-1 [nTPM]":"2.4","Cell RNA - HSkMC [nTPM]":"2.2","Cell RNA - hTCEpi [nTPM]":"0.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.6","Cell RNA - hTERT-HME1 [nTPM]":"0.4","Cell RNA - hTERT-RPE1 [nTPM]":"0.9","Cell RNA - HUVEC TERT2 [nTPM]":"1.2","Cell RNA - JURKAT [nTPM]":"3.0","Cell RNA - K-562 [nTPM]":"3.2","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"4.2","Cell RNA - MCF7 [nTPM]":"0.7","Cell RNA - MOLT-4 [nTPM]":"3.0","Cell RNA - NB-4 [nTPM]":"1.2","Cell RNA - NTERA-2 [nTPM]":"1.8","Cell RNA - OE19 [nTPM]":"1.1","Cell RNA - PC-3 [nTPM]":"0.5","Cell RNA - REH [nTPM]":"1.1","Cell RNA - RH-30 [nTPM]":"1.9","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"2.1","Cell RNA - RT4 [nTPM]":"0.8","Cell RNA - SCLC-21H [nTPM]":"1.5","Cell RNA - SH-SY5Y [nTPM]":"0.9","Cell RNA - SiHa [nTPM]":"1.4","Cell RNA - SK-BR-3 [nTPM]":"2.1","Cell RNA - SK-MEL-30 [nTPM]":"1.7","Cell RNA - SuSa [nTPM]":"2.5","Cell RNA - T-47d [nTPM]":"1.6","Cell RNA - THP-1 [nTPM]":"2.0","Cell RNA - TIME [nTPM]":"2.0","Cell RNA - U-138 MG [nTPM]":"1.9","Cell RNA - U-2 OS [nTPM]":"1.5","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"1.7","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"4.8","Cell RNA - U-87 MG [nTPM]":"1.5","Cell RNA - U-937 [nTPM]":"2.3","Cell RNA - WM-115 [nTPM]":"2.2","Blood RNA - basophil [nTPM]":"13.8","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.3","Brain RNA - basal ganglia [nTPM]":"1.8","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"3.7","Brain RNA - hippocampal formation [nTPM]":"3.8","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"0.8","Brain RNA - midbrain [nTPM]":"0.8","Brain RNA - pons [nTPM]":"0.8","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"3.2","Brain RNA - white matter [nTPM]":"2.0","Single Cell Type RNA - Adipocytes [nTPM]":"1.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.6","Single Cell Type RNA - Fibroblasts [nTPM]":"1.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.9","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CRYM","Gene synonym":["DFNA40"],"Ensembl":"ENSG00000103316","Gene description":"Crystallin mu","Uniprot":["Q14894"],"Chromosome":"16","Position":"21238874-21303083","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"78.7","heart muscle":"175.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"126.0","Ionocytes":"114.0","Muller glia cells":"640.7","Proximal tubular cells":"190.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"14.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"21","RNA blood cell specific nTPM":{"plasmacytoid DC":"82.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"21","RNA blood lineage specific nTPM":{"dendritic cells":"82.0"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"RPTEC TERT1":"100.3"},"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"11","RNA mouse brain regional specific nTPM":{"amygdala":"124.0","basal ganglia":"275.1","cerebral cortex":"124.7","hippocampal formation":"324.3","white matter":"128.4"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019086","HPA030619"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"150000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 5: Muller glia cells - Visual perception","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA019086":"AB_1847260","HPA030619":"AB_2673551"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.75e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.9","Tissue RNA - adrenal gland [nTPM]":"0.8","Tissue RNA - amygdala [nTPM]":"37.4","Tissue RNA - appendix [nTPM]":"0.9","Tissue RNA - basal ganglia [nTPM]":"78.7","Tissue RNA - bone marrow [nTPM]":"1.0","Tissue RNA - breast [nTPM]":"2.7","Tissue RNA - cerebellum [nTPM]":"40.6","Tissue RNA - cerebral cortex [nTPM]":"62.2","Tissue RNA - cervix [nTPM]":"3.7","Tissue RNA - choroid plexus [nTPM]":"13.6","Tissue RNA - colon [nTPM]":"6.9","Tissue RNA - duodenum [nTPM]":"1.6","Tissue RNA - endometrium 1 [nTPM]":"1.0","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"7.6","Tissue RNA - fallopian tube [nTPM]":"1.1","Tissue RNA - gallbladder [nTPM]":"7.0","Tissue RNA - heart muscle [nTPM]":"175.3","Tissue RNA - hippocampal formation [nTPM]":"54.0","Tissue RNA - hypothalamus [nTPM]":"31.6","Tissue RNA - kidney [nTPM]":"64.4","Tissue RNA - liver [nTPM]":"14.2","Tissue RNA - lung [nTPM]":"8.5","Tissue RNA - lymph node [nTPM]":"1.1","Tissue RNA - medulla oblongata [nTPM]":"13.9","Tissue RNA - midbrain [nTPM]":"19.8","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"1.8","Tissue RNA - parathyroid gland [nTPM]":"8.9","Tissue RNA - pituitary gland [nTPM]":"55.6","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"15.6","Tissue RNA - prostate [nTPM]":"35.4","Tissue RNA - rectum [nTPM]":"8.4","Tissue RNA - retina [nTPM]":"54.7","Tissue RNA - salivary gland [nTPM]":"20.6","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"13.4","Tissue RNA - skin 1 [nTPM]":"4.1","Tissue RNA - small intestine [nTPM]":"2.6","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"14.1","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"1.3","Tissue RNA - testis [nTPM]":"5.1","Tissue RNA - thalamus [nTPM]":"20.5","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"3.8","Tissue RNA - urinary bladder [nTPM]":"21.8","Tissue RNA - vagina [nTPM]":"3.6","Tissue RNA - white matter [nTPM]":"31.3","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"4.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"0.7","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"2.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"1.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"1.8","Cell RNA - HaCaT [nTPM]":"0.6","Cell RNA - HAP1 [nTPM]":"5.4","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.8","Cell RNA - HEL [nTPM]":"23.2","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"2.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"2.2","Cell RNA - HSkMC [nTPM]":"0.8","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.8","Cell RNA - hTERT-HME1 [nTPM]":"1.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"0.7","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.9","Cell RNA - NTERA-2 [nTPM]":"9.7","Cell RNA - OE19 [nTPM]":"1.6","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"100.3","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"3.7","Cell RNA - SH-SY5Y [nTPM]":"5.2","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"2.6","Cell RNA - SuSa [nTPM]":"4.8","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.5","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"6.8","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"16.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"2.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"3.9","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"82.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"37.4","Brain RNA - basal ganglia [nTPM]":"78.7","Brain RNA - cerebellum [nTPM]":"40.6","Brain RNA - cerebral cortex [nTPM]":"62.2","Brain RNA - hippocampal formation [nTPM]":"54.0","Brain RNA - hypothalamus [nTPM]":"31.6","Brain RNA - medulla oblongata [nTPM]":"13.9","Brain RNA - midbrain [nTPM]":"19.8","Brain RNA - pons [nTPM]":"15.6","Brain RNA - spinal cord [nTPM]":"14.1","Brain RNA - thalamus [nTPM]":"20.5","Brain RNA - white matter [nTPM]":"31.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.1","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"4.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"25.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"6.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"126.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"56.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"11.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"19.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.5","Single Cell Type RNA - Endothelial cells [nTPM]":"3.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"4.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"43.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"7.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.7","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"1.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"8.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.6","Single Cell Type RNA - Ionocytes [nTPM]":"114.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"12.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.5","Single Cell Type RNA - Melanocytes [nTPM]":"33.8","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"640.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"2.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"190.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"26.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.3","Single Cell Type RNA - Spermatocytes [nTPM]":"6.7","Single Cell Type RNA - Spermatogonia [nTPM]":"7.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.2","Single Cell Type RNA - Urothelial cells [nTPM]":"68.0"},{"Gene":"CSGALNACT1","Gene synonym":["ChGn","CSGalNAcT-1","FLJ11264"],"Ensembl":"ENSG00000147408","Gene description":"Chondroitin sulfate N-acetylgalactosaminyltransferase 1","Uniprot":["Q8TDX6"],"Chromosome":"8","Position":"19404161-19758029","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"thyroid gland":"86.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"494.3","Excitatory neurons":"144.4","Granulosa cells":"214.1","Microglial cells":"224.9","Oligodendrocyte precursor cells":"355.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"22.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"62.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"44.5","granulocytes":"24.9","T-cells":"62.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"57.8","BJ hTERT+":"32.3","GAMG":"22.9","RPTEC TERT1":"39.6","U-2197":"36.8","U-87 MG":"26.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA068462"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA068462":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Tissue RNA - adipose tissue [nTPM]":"19.4","Tissue RNA - adrenal gland [nTPM]":"12.5","Tissue RNA - amygdala [nTPM]":"20.3","Tissue RNA - appendix [nTPM]":"8.8","Tissue RNA - basal ganglia [nTPM]":"15.7","Tissue RNA - bone marrow [nTPM]":"11.1","Tissue RNA - breast [nTPM]":"7.4","Tissue RNA - cerebellum [nTPM]":"4.8","Tissue RNA - cerebral cortex [nTPM]":"18.3","Tissue RNA - cervix [nTPM]":"18.0","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"4.7","Tissue RNA - duodenum [nTPM]":"3.5","Tissue RNA - endometrium 1 [nTPM]":"7.0","Tissue RNA - epididymis [nTPM]":"5.4","Tissue RNA - esophagus [nTPM]":"31.2","Tissue RNA - fallopian tube [nTPM]":"11.8","Tissue RNA - gallbladder [nTPM]":"16.1","Tissue RNA - heart muscle [nTPM]":"35.8","Tissue RNA - hippocampal formation [nTPM]":"16.3","Tissue RNA - hypothalamus [nTPM]":"11.5","Tissue RNA - kidney [nTPM]":"6.0","Tissue RNA - liver [nTPM]":"2.8","Tissue RNA - lung [nTPM]":"11.7","Tissue RNA - lymph node [nTPM]":"7.6","Tissue RNA - medulla oblongata [nTPM]":"6.3","Tissue RNA - midbrain [nTPM]":"11.2","Tissue RNA - ovary [nTPM]":"57.0","Tissue RNA - pancreas [nTPM]":"7.9","Tissue RNA - parathyroid gland [nTPM]":"11.4","Tissue RNA - pituitary gland [nTPM]":"3.0","Tissue RNA - placenta [nTPM]":"38.8","Tissue RNA - pons [nTPM]":"7.6","Tissue RNA - prostate [nTPM]":"31.8","Tissue RNA - rectum [nTPM]":"2.5","Tissue RNA - retina [nTPM]":"2.5","Tissue RNA - salivary gland [nTPM]":"6.8","Tissue RNA - seminal vesicle [nTPM]":"9.8","Tissue RNA - skeletal muscle [nTPM]":"5.8","Tissue RNA - skin 1 [nTPM]":"4.8","Tissue RNA - small intestine [nTPM]":"4.7","Tissue RNA - smooth muscle [nTPM]":"12.3","Tissue RNA - spinal cord [nTPM]":"6.7","Tissue RNA - spleen [nTPM]":"8.7","Tissue RNA - stomach 1 [nTPM]":"6.9","Tissue RNA - testis [nTPM]":"2.8","Tissue RNA - thalamus [nTPM]":"8.9","Tissue RNA - thymus [nTPM]":"11.7","Tissue RNA - thyroid gland [nTPM]":"86.7","Tissue RNA - tongue [nTPM]":"11.0","Tissue RNA - tonsil [nTPM]":"8.8","Tissue RNA - urinary bladder [nTPM]":"23.4","Tissue RNA - vagina [nTPM]":"8.1","Tissue RNA - white matter [nTPM]":"10.7","Cell RNA - A-431 [nTPM]":"2.1","Cell RNA - A549 [nTPM]":"57.8","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"9.3","Cell RNA - ASC TERT1 [nTPM]":"2.1","Cell RNA - BEWO [nTPM]":"7.9","Cell RNA - BJ [nTPM]":"1.4","Cell RNA - BJ hTERT+ [nTPM]":"32.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"3.1","Cell RNA - CAPAN-2 [nTPM]":"1.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"22.9","Cell RNA - HaCaT [nTPM]":"0.7","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"7.5","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"16.2","Cell RNA - Hep G2 [nTPM]":"1.9","Cell RNA - HHSteC [nTPM]":"4.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.9","Cell RNA - hTCEpi [nTPM]":"1.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.7","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.4","Cell RNA - HUVEC TERT2 [nTPM]":"11.6","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"2.6","Cell RNA - MOLT-4 [nTPM]":"2.9","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"8.3","Cell RNA - PC-3 [nTPM]":"1.7","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"39.6","Cell RNA - RT4 [nTPM]":"1.6","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"17.2","Cell RNA - SK-BR-3 [nTPM]":"6.9","Cell RNA - SK-MEL-30 [nTPM]":"2.4","Cell RNA - SuSa [nTPM]":"1.5","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"1.0","Cell RNA - U-138 MG [nTPM]":"1.1","Cell RNA - U-2 OS [nTPM]":"1.3","Cell RNA - U-2197 [nTPM]":"36.8","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"26.0","Cell RNA - U-937 [nTPM]":"3.4","Cell RNA - WM-115 [nTPM]":"11.4","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"2.9","Blood RNA - eosinophil [nTPM]":"24.9","Blood RNA - gdT-cell [nTPM]":"5.6","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"44.5","Blood RNA - memory CD4 T-cell [nTPM]":"25.7","Blood RNA - memory CD8 T-cell [nTPM]":"8.5","Blood RNA - myeloid DC [nTPM]":"2.8","Blood RNA - naive B-cell [nTPM]":"15.9","Blood RNA - naive CD4 T-cell [nTPM]":"44.6","Blood RNA - naive CD8 T-cell [nTPM]":"11.6","Blood RNA - neutrophil [nTPM]":"15.6","Blood RNA - NK-cell [nTPM]":"8.4","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"4.2","Blood RNA - T-reg [nTPM]":"62.6","Blood RNA - total PBMC [nTPM]":"11.7","Brain RNA - amygdala [nTPM]":"20.3","Brain RNA - basal ganglia [nTPM]":"15.7","Brain RNA - cerebellum [nTPM]":"4.8","Brain RNA - cerebral cortex [nTPM]":"18.3","Brain RNA - hippocampal formation [nTPM]":"16.3","Brain RNA - hypothalamus [nTPM]":"11.5","Brain RNA - medulla oblongata [nTPM]":"6.3","Brain RNA - midbrain [nTPM]":"11.2","Brain RNA - pons [nTPM]":"7.6","Brain RNA - spinal cord [nTPM]":"6.7","Brain RNA - thalamus [nTPM]":"8.9","Brain RNA - white matter [nTPM]":"10.7","Single Cell Type RNA - Adipocytes [nTPM]":"33.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"494.3","Single Cell Type RNA - B-cells [nTPM]":"27.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"45.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - dendritic cells [nTPM]":"6.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.7","Single Cell Type RNA - Early spermatids [nTPM]":"6.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.2","Single Cell Type RNA - Endothelial cells [nTPM]":"38.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"3.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"144.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.6","Single Cell Type RNA - Fibroblasts [nTPM]":"20.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"214.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.8","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"76.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"27.4","Single Cell Type RNA - Langerhans cells [nTPM]":"6.5","Single Cell Type RNA - Late spermatids [nTPM]":"7.4","Single Cell Type RNA - Leydig cells [nTPM]":"5.3","Single Cell Type RNA - Macrophages [nTPM]":"14.1","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"224.9","Single Cell Type RNA - monocytes [nTPM]":"3.5","Single Cell Type RNA - Muller glia cells [nTPM]":"1.0","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"355.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"12.0","Single Cell Type RNA - Plasma cells [nTPM]":"21.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"21.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.3","Single Cell Type RNA - T-cells [nTPM]":"9.6","Single Cell Type RNA - Theca cells [nTPM]":"77.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"2.8"},{"Gene":"CSNK1D","Gene synonym":["CKID","CKIdelta","HCKID"],"Ensembl":"ENSG00000141551","Gene description":"Casein kinase 1 delta","Uniprot":["P48730"],"Chromosome":"17","Position":"82239023-82273731","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Biological rhythms","Wnt signaling pathway"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"312.5","Late spermatids":"775.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015410"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB015410":"AB_831049"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.04e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.38e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.62e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.34e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-2"},"Tissue RNA - adipose tissue [nTPM]":"46.7","Tissue RNA - adrenal gland [nTPM]":"57.0","Tissue RNA - amygdala [nTPM]":"36.9","Tissue RNA - appendix [nTPM]":"28.9","Tissue RNA - basal ganglia [nTPM]":"36.9","Tissue RNA - bone marrow [nTPM]":"25.9","Tissue RNA - breast [nTPM]":"42.3","Tissue RNA - cerebellum [nTPM]":"34.4","Tissue RNA - cerebral cortex [nTPM]":"37.9","Tissue RNA - cervix [nTPM]":"45.3","Tissue RNA - choroid plexus [nTPM]":"30.3","Tissue RNA - colon [nTPM]":"57.1","Tissue RNA - duodenum [nTPM]":"35.1","Tissue RNA - endometrium 1 [nTPM]":"56.6","Tissue RNA - epididymis [nTPM]":"26.7","Tissue RNA - esophagus [nTPM]":"50.8","Tissue RNA - fallopian tube [nTPM]":"45.3","Tissue RNA - gallbladder [nTPM]":"24.8","Tissue RNA - heart muscle [nTPM]":"42.4","Tissue RNA - hippocampal formation [nTPM]":"39.0","Tissue RNA - hypothalamus [nTPM]":"40.2","Tissue RNA - kidney [nTPM]":"45.5","Tissue RNA - liver [nTPM]":"40.9","Tissue RNA - lung [nTPM]":"45.3","Tissue RNA - lymph node [nTPM]":"30.8","Tissue RNA - medulla oblongata [nTPM]":"37.2","Tissue RNA - midbrain [nTPM]":"37.6","Tissue RNA - ovary [nTPM]":"43.1","Tissue RNA - pancreas [nTPM]":"47.5","Tissue RNA - parathyroid gland [nTPM]":"43.1","Tissue RNA - pituitary gland [nTPM]":"54.2","Tissue RNA - placenta [nTPM]":"30.2","Tissue RNA - pons [nTPM]":"36.3","Tissue RNA - prostate [nTPM]":"51.8","Tissue RNA - rectum [nTPM]":"20.0","Tissue RNA - retina [nTPM]":"15.1","Tissue RNA - salivary gland [nTPM]":"48.6","Tissue RNA - seminal vesicle [nTPM]":"36.8","Tissue RNA - skeletal muscle [nTPM]":"88.9","Tissue RNA - skin 1 [nTPM]":"36.4","Tissue RNA - small intestine [nTPM]":"50.9","Tissue RNA - smooth muscle [nTPM]":"29.0","Tissue RNA - spinal cord [nTPM]":"36.3","Tissue RNA - spleen [nTPM]":"56.3","Tissue RNA - stomach 1 [nTPM]":"49.3","Tissue RNA - testis [nTPM]":"60.7","Tissue RNA - thalamus [nTPM]":"42.6","Tissue RNA - thymus [nTPM]":"34.0","Tissue RNA - thyroid gland [nTPM]":"44.7","Tissue RNA - tongue [nTPM]":"38.7","Tissue RNA - tonsil [nTPM]":"22.8","Tissue RNA - urinary bladder [nTPM]":"49.0","Tissue RNA - vagina [nTPM]":"37.0","Tissue RNA - white matter [nTPM]":"32.9","Cell RNA - A-431 [nTPM]":"60.3","Cell RNA - A549 [nTPM]":"70.9","Cell RNA - AF22 [nTPM]":"39.5","Cell RNA - AN3-CA [nTPM]":"54.7","Cell RNA - ASC diff [nTPM]":"50.8","Cell RNA - ASC TERT1 [nTPM]":"53.9","Cell RNA - BEWO [nTPM]":"77.7","Cell RNA - BJ [nTPM]":"85.1","Cell RNA - BJ hTERT+ [nTPM]":"54.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"61.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"56.8","Cell RNA - CACO-2 [nTPM]":"58.6","Cell RNA - CAPAN-2 [nTPM]":"49.4","Cell RNA - Daudi [nTPM]":"55.0","Cell RNA - EFO-21 [nTPM]":"66.3","Cell RNA - fHDF\/TERT166 [nTPM]":"62.5","Cell RNA - GAMG [nTPM]":"64.8","Cell RNA - HaCaT [nTPM]":"57.1","Cell RNA - HAP1 [nTPM]":"37.4","Cell RNA - HBEC3-KT [nTPM]":"88.3","Cell RNA - HBF TERT88 [nTPM]":"48.9","Cell RNA - HDLM-2 [nTPM]":"47.0","Cell RNA - HEK 293 [nTPM]":"90.5","Cell RNA - HEL [nTPM]":"68.5","Cell RNA - HeLa [nTPM]":"53.4","Cell RNA - Hep G2 [nTPM]":"63.7","Cell RNA - HHSteC [nTPM]":"146.9","Cell RNA - HL-60 [nTPM]":"56.9","Cell RNA - HMC-1 [nTPM]":"50.4","Cell RNA - HSkMC [nTPM]":"81.9","Cell RNA - hTCEpi [nTPM]":"61.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"41.6","Cell RNA - hTERT-HME1 [nTPM]":"61.3","Cell RNA - hTERT-RPE1 [nTPM]":"76.0","Cell RNA - HUVEC TERT2 [nTPM]":"90.0","Cell RNA - JURKAT [nTPM]":"39.5","Cell RNA - K-562 [nTPM]":"78.5","Cell RNA - Karpas-707 [nTPM]":"28.4","Cell RNA - LHCN-M2 [nTPM]":"58.5","Cell RNA - MCF7 [nTPM]":"70.6","Cell RNA - MOLT-4 [nTPM]":"73.7","Cell RNA - NB-4 [nTPM]":"59.3","Cell RNA - NTERA-2 [nTPM]":"42.2","Cell RNA - OE19 [nTPM]":"71.3","Cell RNA - PC-3 [nTPM]":"108.6","Cell RNA - REH [nTPM]":"62.6","Cell RNA - RH-30 [nTPM]":"48.7","Cell RNA - RPMI-8226 [nTPM]":"49.7","Cell RNA - RPTEC TERT1 [nTPM]":"64.8","Cell RNA - RT4 [nTPM]":"93.4","Cell RNA - SCLC-21H [nTPM]":"48.5","Cell RNA - SH-SY5Y [nTPM]":"87.4","Cell RNA - SiHa [nTPM]":"100.4","Cell RNA - SK-BR-3 [nTPM]":"85.5","Cell RNA - SK-MEL-30 [nTPM]":"97.7","Cell RNA - SuSa [nTPM]":"54.3","Cell RNA - T-47d [nTPM]":"61.5","Cell RNA - THP-1 [nTPM]":"73.0","Cell RNA - TIME [nTPM]":"95.6","Cell RNA - U-138 MG [nTPM]":"86.9","Cell RNA - U-2 OS [nTPM]":"77.3","Cell RNA - U-2197 [nTPM]":"76.2","Cell RNA - U-251 MG [nTPM]":"67.0","Cell RNA - U-266\/70 [nTPM]":"61.0","Cell RNA - U-266\/84 [nTPM]":"32.1","Cell RNA - U-698 [nTPM]":"58.4","Cell RNA - U-87 MG [nTPM]":"69.5","Cell RNA - U-937 [nTPM]":"48.1","Cell RNA - WM-115 [nTPM]":"64.7","Blood RNA - basophil [nTPM]":"8.8","Blood RNA - classical monocyte [nTPM]":"20.8","Blood RNA - eosinophil [nTPM]":"27.4","Blood RNA - gdT-cell [nTPM]":"12.3","Blood RNA - intermediate monocyte [nTPM]":"21.3","Blood RNA - MAIT T-cell [nTPM]":"11.8","Blood RNA - memory B-cell [nTPM]":"11.1","Blood RNA - memory CD4 T-cell [nTPM]":"9.6","Blood RNA - memory CD8 T-cell [nTPM]":"12.1","Blood RNA - myeloid DC [nTPM]":"20.1","Blood RNA - naive B-cell [nTPM]":"9.0","Blood RNA - naive CD4 T-cell [nTPM]":"8.1","Blood RNA - naive CD8 T-cell [nTPM]":"8.7","Blood RNA - neutrophil [nTPM]":"50.4","Blood RNA - NK-cell [nTPM]":"15.3","Blood RNA - non-classical monocyte [nTPM]":"20.3","Blood RNA - plasmacytoid DC [nTPM]":"9.6","Blood RNA - T-reg [nTPM]":"9.2","Blood RNA - total PBMC [nTPM]":"15.4","Brain RNA - amygdala [nTPM]":"36.9","Brain RNA - basal ganglia [nTPM]":"36.9","Brain RNA - cerebellum [nTPM]":"34.4","Brain RNA - cerebral cortex [nTPM]":"37.9","Brain RNA - hippocampal formation [nTPM]":"39.0","Brain RNA - hypothalamus [nTPM]":"40.2","Brain RNA - medulla oblongata [nTPM]":"37.2","Brain RNA - midbrain [nTPM]":"37.6","Brain RNA - pons [nTPM]":"36.3","Brain RNA - spinal cord [nTPM]":"36.3","Brain RNA - thalamus [nTPM]":"42.6","Brain RNA - white matter [nTPM]":"32.9","Single Cell Type RNA - Adipocytes [nTPM]":"65.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"54.3","Single Cell Type RNA - Astrocytes [nTPM]":"36.6","Single Cell Type RNA - B-cells [nTPM]":"81.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"56.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"116.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"58.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"52.9","Single Cell Type RNA - Bipolar cells [nTPM]":"46.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"59.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"51.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"31.5","Single Cell Type RNA - Club cells [nTPM]":"65.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"42.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"61.8","Single Cell Type RNA - dendritic cells [nTPM]":"101.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"105.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"71.6","Single Cell Type RNA - Early spermatids [nTPM]":"312.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"69.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"54.0","Single Cell Type RNA - Endothelial cells [nTPM]":"54.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"46.2","Single Cell Type RNA - Erythroid cells [nTPM]":"32.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"24.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"69.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"95.2","Single Cell Type RNA - Fibroblasts [nTPM]":"42.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"87.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"93.2","Single Cell Type RNA - granulocytes [nTPM]":"60.1","Single Cell Type RNA - Granulosa cells [nTPM]":"45.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"42.5","Single Cell Type RNA - Hepatocytes [nTPM]":"33.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"65.3","Single Cell Type RNA - Horizontal cells [nTPM]":"95.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"62.8","Single Cell Type RNA - Ionocytes [nTPM]":"67.1","Single Cell Type RNA - Kupffer cells [nTPM]":"51.5","Single Cell Type RNA - Langerhans cells [nTPM]":"83.8","Single Cell Type RNA - Late spermatids [nTPM]":"775.6","Single Cell Type RNA - Leydig cells [nTPM]":"30.1","Single Cell Type RNA - Macrophages [nTPM]":"75.7","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"24.4","Single Cell Type RNA - monocytes [nTPM]":"65.8","Single Cell Type RNA - Muller glia cells [nTPM]":"28.7","Single Cell Type RNA - NK-cells [nTPM]":"79.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"24.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"87.7","Single Cell Type RNA - Paneth cells [nTPM]":"83.2","Single Cell Type RNA - Peritubular cells [nTPM]":"40.3","Single Cell Type RNA - Plasma cells [nTPM]":"80.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"90.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"94.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"43.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"66.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"54.4","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"78.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"57.5","Single Cell Type RNA - Spermatocytes [nTPM]":"55.1","Single Cell Type RNA - Spermatogonia [nTPM]":"29.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"44.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"48.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"126.6","Single Cell Type RNA - T-cells [nTPM]":"87.6","Single Cell Type RNA - Theca cells [nTPM]":"46.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"56.7","Single Cell Type RNA - Urothelial cells [nTPM]":"118.6"},{"Gene":"CSNK2A1","Gene synonym":["Cka1","Cka2"],"Ensembl":"ENSG00000101266","Gene description":"Casein kinase 2 alpha 1","Uniprot":["P68400"],"Chromosome":"20","Position":"472498-543835","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Biological rhythms","Cell cycle","Transcription","Transcription regulation","Wnt signaling pathway"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB020680","HPA059206","HPA061698","CAB069395"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB020680":null,"CAB069395":"AB_1611912","HPA059206":"AB_2683948","HPA061698":"AB_2732667"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.11e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-2"},"Tissue RNA - adipose tissue [nTPM]":"36.1","Tissue RNA - adrenal gland [nTPM]":"32.6","Tissue RNA - amygdala [nTPM]":"20.9","Tissue RNA - appendix [nTPM]":"38.6","Tissue RNA - basal ganglia [nTPM]":"23.2","Tissue RNA - bone marrow [nTPM]":"34.0","Tissue RNA - breast [nTPM]":"35.9","Tissue RNA - cerebellum [nTPM]":"28.2","Tissue RNA - cerebral cortex [nTPM]":"29.6","Tissue RNA - cervix [nTPM]":"36.5","Tissue RNA - choroid plexus [nTPM]":"29.3","Tissue RNA - colon [nTPM]":"48.3","Tissue RNA - duodenum [nTPM]":"39.1","Tissue RNA - endometrium 1 [nTPM]":"35.8","Tissue RNA - epididymis [nTPM]":"26.6","Tissue RNA - esophagus [nTPM]":"50.0","Tissue RNA - fallopian tube [nTPM]":"39.9","Tissue RNA - gallbladder [nTPM]":"31.3","Tissue RNA - heart muscle [nTPM]":"54.0","Tissue RNA - hippocampal formation [nTPM]":"25.7","Tissue RNA - hypothalamus [nTPM]":"21.0","Tissue RNA - kidney [nTPM]":"41.0","Tissue RNA - liver [nTPM]":"31.8","Tissue RNA - lung [nTPM]":"31.6","Tissue RNA - lymph node [nTPM]":"41.2","Tissue RNA - medulla oblongata [nTPM]":"20.6","Tissue RNA - midbrain [nTPM]":"21.1","Tissue RNA - ovary [nTPM]":"41.5","Tissue RNA - pancreas [nTPM]":"46.9","Tissue RNA - parathyroid gland [nTPM]":"59.1","Tissue RNA - pituitary gland [nTPM]":"21.2","Tissue RNA - placenta [nTPM]":"42.4","Tissue RNA - pons [nTPM]":"21.1","Tissue RNA - prostate [nTPM]":"35.8","Tissue RNA - rectum [nTPM]":"40.7","Tissue RNA - retina [nTPM]":"32.9","Tissue RNA - salivary gland [nTPM]":"41.1","Tissue RNA - seminal vesicle [nTPM]":"37.7","Tissue RNA - skeletal muscle [nTPM]":"110.5","Tissue RNA - skin 1 [nTPM]":"34.2","Tissue RNA - small intestine [nTPM]":"40.5","Tissue RNA - smooth muscle [nTPM]":"39.1","Tissue RNA - spinal cord [nTPM]":"18.8","Tissue RNA - spleen [nTPM]":"30.2","Tissue RNA - stomach 1 [nTPM]":"49.5","Tissue RNA - testis [nTPM]":"65.2","Tissue RNA - thalamus [nTPM]":"22.3","Tissue RNA - thymus [nTPM]":"51.6","Tissue RNA - thyroid gland [nTPM]":"39.6","Tissue RNA - tongue [nTPM]":"86.4","Tissue RNA - tonsil [nTPM]":"46.6","Tissue RNA - urinary bladder [nTPM]":"47.4","Tissue RNA - vagina [nTPM]":"28.5","Tissue RNA - white matter [nTPM]":"27.3","Cell RNA - A-431 [nTPM]":"209.5","Cell RNA - A549 [nTPM]":"170.4","Cell RNA - AF22 [nTPM]":"152.9","Cell RNA - AN3-CA [nTPM]":"96.0","Cell RNA - ASC diff [nTPM]":"61.1","Cell RNA - ASC TERT1 [nTPM]":"103.8","Cell RNA - BEWO [nTPM]":"103.5","Cell RNA - BJ [nTPM]":"117.9","Cell RNA - BJ hTERT+ [nTPM]":"116.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"125.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"139.5","Cell RNA - CACO-2 [nTPM]":"178.5","Cell RNA - CAPAN-2 [nTPM]":"120.0","Cell RNA - Daudi [nTPM]":"179.1","Cell RNA - EFO-21 [nTPM]":"74.2","Cell RNA - fHDF\/TERT166 [nTPM]":"90.1","Cell RNA - GAMG [nTPM]":"179.1","Cell RNA - HaCaT [nTPM]":"147.8","Cell RNA - HAP1 [nTPM]":"162.1","Cell RNA - HBEC3-KT [nTPM]":"167.4","Cell RNA - HBF TERT88 [nTPM]":"187.2","Cell RNA - HDLM-2 [nTPM]":"62.6","Cell RNA - HEK 293 [nTPM]":"57.7","Cell RNA - HEL [nTPM]":"247.3","Cell RNA - HeLa [nTPM]":"44.7","Cell RNA - Hep G2 [nTPM]":"177.7","Cell RNA - HHSteC [nTPM]":"102.5","Cell RNA - HL-60 [nTPM]":"228.1","Cell RNA - HMC-1 [nTPM]":"51.3","Cell RNA - HSkMC [nTPM]":"99.5","Cell RNA - hTCEpi [nTPM]":"173.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"105.8","Cell RNA - hTERT-HME1 [nTPM]":"316.0","Cell RNA - hTERT-RPE1 [nTPM]":"122.2","Cell RNA - HUVEC TERT2 [nTPM]":"139.5","Cell RNA - JURKAT [nTPM]":"146.4","Cell RNA - K-562 [nTPM]":"248.9","Cell RNA - Karpas-707 [nTPM]":"112.6","Cell RNA - LHCN-M2 [nTPM]":"123.8","Cell RNA - MCF7 [nTPM]":"64.2","Cell RNA - MOLT-4 [nTPM]":"262.0","Cell RNA - NB-4 [nTPM]":"73.7","Cell RNA - NTERA-2 [nTPM]":"227.4","Cell RNA - OE19 [nTPM]":"173.4","Cell RNA - PC-3 [nTPM]":"97.6","Cell RNA - REH [nTPM]":"149.8","Cell RNA - RH-30 [nTPM]":"140.5","Cell RNA - RPMI-8226 [nTPM]":"140.9","Cell RNA - RPTEC TERT1 [nTPM]":"112.9","Cell RNA - RT4 [nTPM]":"128.5","Cell RNA - SCLC-21H [nTPM]":"163.9","Cell RNA - SH-SY5Y [nTPM]":"132.3","Cell RNA - SiHa [nTPM]":"97.2","Cell RNA - SK-BR-3 [nTPM]":"184.0","Cell RNA - SK-MEL-30 [nTPM]":"174.8","Cell RNA - SuSa [nTPM]":"120.7","Cell RNA - T-47d [nTPM]":"120.4","Cell RNA - THP-1 [nTPM]":"83.9","Cell RNA - TIME [nTPM]":"142.7","Cell RNA - U-138 MG [nTPM]":"136.0","Cell RNA - U-2 OS [nTPM]":"118.4","Cell RNA - U-2197 [nTPM]":"90.0","Cell RNA - U-251 MG [nTPM]":"178.5","Cell RNA - U-266\/70 [nTPM]":"120.6","Cell RNA - U-266\/84 [nTPM]":"311.8","Cell RNA - U-698 [nTPM]":"174.1","Cell RNA - U-87 MG [nTPM]":"65.8","Cell RNA - U-937 [nTPM]":"119.5","Cell RNA - WM-115 [nTPM]":"138.6","Blood RNA - basophil [nTPM]":"40.5","Blood RNA - classical monocyte [nTPM]":"23.8","Blood RNA - eosinophil [nTPM]":"28.7","Blood RNA - gdT-cell [nTPM]":"18.2","Blood RNA - intermediate monocyte [nTPM]":"32.3","Blood RNA - MAIT T-cell [nTPM]":"22.4","Blood RNA - memory B-cell [nTPM]":"23.0","Blood RNA - memory CD4 T-cell [nTPM]":"18.0","Blood RNA - memory CD8 T-cell [nTPM]":"17.6","Blood RNA - myeloid DC [nTPM]":"31.5","Blood RNA - naive B-cell [nTPM]":"22.5","Blood RNA - naive CD4 T-cell [nTPM]":"17.9","Blood RNA - naive CD8 T-cell [nTPM]":"17.4","Blood RNA - neutrophil [nTPM]":"14.9","Blood RNA - NK-cell [nTPM]":"25.1","Blood RNA - non-classical monocyte [nTPM]":"33.5","Blood RNA - plasmacytoid DC [nTPM]":"25.7","Blood RNA - T-reg [nTPM]":"20.4","Blood RNA - total PBMC [nTPM]":"20.8","Brain RNA - amygdala [nTPM]":"20.9","Brain RNA - basal ganglia [nTPM]":"23.2","Brain RNA - cerebellum [nTPM]":"28.2","Brain RNA - cerebral cortex [nTPM]":"29.6","Brain RNA - hippocampal formation [nTPM]":"25.7","Brain RNA - hypothalamus [nTPM]":"21.0","Brain RNA - medulla oblongata [nTPM]":"20.6","Brain RNA - midbrain [nTPM]":"21.1","Brain RNA - pons [nTPM]":"21.1","Brain RNA - spinal cord [nTPM]":"18.8","Brain RNA - thalamus [nTPM]":"22.3","Brain RNA - white matter [nTPM]":"27.3","Single Cell Type RNA - Adipocytes [nTPM]":"50.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"64.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"84.6","Single Cell Type RNA - Astrocytes [nTPM]":"51.9","Single Cell Type RNA - B-cells [nTPM]":"46.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"41.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"40.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"43.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"45.5","Single Cell Type RNA - Bipolar cells [nTPM]":"49.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"42.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"36.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"59.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"41.5","Single Cell Type RNA - Club cells [nTPM]":"75.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"42.2","Single Cell Type RNA - dendritic cells [nTPM]":"50.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"43.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"41.1","Single Cell Type RNA - Ductal cells [nTPM]":"68.5","Single Cell Type RNA - Early spermatids [nTPM]":"135.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"67.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"77.0","Single Cell Type RNA - Endothelial cells [nTPM]":"44.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"35.2","Single Cell Type RNA - Erythroid cells [nTPM]":"59.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"65.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"50.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"54.4","Single Cell Type RNA - Fibroblasts [nTPM]":"46.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"40.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"75.7","Single Cell Type RNA - granulocytes [nTPM]":"63.8","Single Cell Type RNA - Granulosa cells [nTPM]":"108.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"27.1","Single Cell Type RNA - Hepatocytes [nTPM]":"31.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"33.2","Single Cell Type RNA - Horizontal cells [nTPM]":"60.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"69.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"41.8","Single Cell Type RNA - Ionocytes [nTPM]":"46.8","Single Cell Type RNA - Kupffer cells [nTPM]":"39.2","Single Cell Type RNA - Langerhans cells [nTPM]":"30.3","Single Cell Type RNA - Late spermatids [nTPM]":"140.0","Single Cell Type RNA - Leydig cells [nTPM]":"41.0","Single Cell Type RNA - Macrophages [nTPM]":"45.3","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"51.5","Single Cell Type RNA - monocytes [nTPM]":"61.7","Single Cell Type RNA - Muller glia cells [nTPM]":"38.6","Single Cell Type RNA - NK-cells [nTPM]":"37.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"73.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"73.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"66.6","Single Cell Type RNA - Paneth cells [nTPM]":"34.4","Single Cell Type RNA - Peritubular cells [nTPM]":"36.9","Single Cell Type RNA - Plasma cells [nTPM]":"49.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"57.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"43.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"68.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"65.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"27.8","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"43.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"56.8","Single Cell Type RNA - Spermatocytes [nTPM]":"94.2","Single Cell Type RNA - Spermatogonia [nTPM]":"68.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"52.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"50.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"61.4","Single Cell Type RNA - T-cells [nTPM]":"38.9","Single Cell Type RNA - Theca cells [nTPM]":"81.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"40.6","Single Cell Type RNA - Urothelial cells [nTPM]":"59.4"},{"Gene":"CSTB","Gene synonym":["CST6","EPM1","PME","STFB"],"Ensembl":"ENSG00000160213","Gene description":"Cystatin B","Uniprot":["P04080"],"Chromosome":"21","Position":"43772511-43776330","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":["Protease inhibitor","Thiol protease inhibitor"],"Disease involvement":["Cancer-related genes","Disease variant","Epilepsy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"esophagus":"11304.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"5910.7","Club cells":"4352.8","Hofbauer cells":"2827.7","Squamous epithelial cells":"4910.2","Urothelial cells":"3198.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RT4":"2798.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017380","CAB047320","HPA058557"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"8700000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"CAB047320":null,"HPA017380":"AB_1847414","HPA058557":"AB_2683755"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.66e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.10e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Tissue RNA - adipose tissue [nTPM]":"224.3","Tissue RNA - adrenal gland [nTPM]":"165.6","Tissue RNA - amygdala [nTPM]":"254.1","Tissue RNA - appendix [nTPM]":"141.6","Tissue RNA - basal ganglia [nTPM]":"253.6","Tissue RNA - bone marrow [nTPM]":"73.8","Tissue RNA - breast [nTPM]":"161.9","Tissue RNA - cerebellum [nTPM]":"255.4","Tissue RNA - cerebral cortex [nTPM]":"314.6","Tissue RNA - cervix [nTPM]":"585.8","Tissue RNA - choroid plexus [nTPM]":"275.2","Tissue RNA - colon [nTPM]":"243.8","Tissue RNA - duodenum [nTPM]":"122.9","Tissue RNA - endometrium 1 [nTPM]":"90.1","Tissue RNA - epididymis [nTPM]":"175.0","Tissue RNA - esophagus [nTPM]":"11304.7","Tissue RNA - fallopian tube [nTPM]":"154.1","Tissue RNA - gallbladder [nTPM]":"150.7","Tissue RNA - heart muscle [nTPM]":"192.2","Tissue RNA - hippocampal formation [nTPM]":"252.8","Tissue RNA - hypothalamus [nTPM]":"263.0","Tissue RNA - kidney [nTPM]":"144.7","Tissue RNA - liver [nTPM]":"189.4","Tissue RNA - lung [nTPM]":"290.1","Tissue RNA - lymph node [nTPM]":"176.4","Tissue RNA - medulla oblongata [nTPM]":"258.4","Tissue RNA - midbrain [nTPM]":"257.8","Tissue RNA - ovary [nTPM]":"136.1","Tissue RNA - pancreas [nTPM]":"116.2","Tissue RNA - parathyroid gland [nTPM]":"154.4","Tissue RNA - pituitary gland [nTPM]":"70.1","Tissue RNA - placenta [nTPM]":"132.1","Tissue RNA - pons [nTPM]":"259.6","Tissue RNA - prostate [nTPM]":"137.3","Tissue RNA - rectum [nTPM]":"194.7","Tissue RNA - retina [nTPM]":"78.9","Tissue RNA - salivary gland [nTPM]":"738.3","Tissue RNA - seminal vesicle [nTPM]":"138.6","Tissue RNA - skeletal muscle [nTPM]":"100.1","Tissue RNA - skin 1 [nTPM]":"256.9","Tissue RNA - small intestine [nTPM]":"135.6","Tissue RNA - smooth muscle [nTPM]":"110.4","Tissue RNA - spinal cord [nTPM]":"257.5","Tissue RNA - spleen [nTPM]":"125.8","Tissue RNA - stomach 1 [nTPM]":"249.9","Tissue RNA - testis [nTPM]":"71.7","Tissue RNA - thalamus [nTPM]":"262.8","Tissue RNA - thymus [nTPM]":"268.2","Tissue RNA - thyroid gland [nTPM]":"147.9","Tissue RNA - tongue [nTPM]":"197.4","Tissue RNA - tonsil [nTPM]":"1484.9","Tissue RNA - urinary bladder [nTPM]":"611.8","Tissue RNA - vagina [nTPM]":"1001.9","Tissue RNA - white matter [nTPM]":"262.9","Cell RNA - A-431 [nTPM]":"1573.6","Cell RNA - A549 [nTPM]":"495.5","Cell RNA - AF22 [nTPM]":"146.3","Cell RNA - AN3-CA [nTPM]":"188.1","Cell RNA - ASC diff [nTPM]":"874.5","Cell RNA - ASC TERT1 [nTPM]":"742.6","Cell RNA - BEWO [nTPM]":"379.6","Cell RNA - BJ [nTPM]":"310.1","Cell RNA - BJ hTERT+ [nTPM]":"431.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"230.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"230.6","Cell RNA - CACO-2 [nTPM]":"401.6","Cell RNA - CAPAN-2 [nTPM]":"868.6","Cell RNA - Daudi [nTPM]":"123.0","Cell RNA - EFO-21 [nTPM]":"245.8","Cell RNA - fHDF\/TERT166 [nTPM]":"570.1","Cell RNA - GAMG [nTPM]":"1814.0","Cell RNA - HaCaT [nTPM]":"260.5","Cell RNA - HAP1 [nTPM]":"384.4","Cell RNA - HBEC3-KT [nTPM]":"405.7","Cell RNA - HBF TERT88 [nTPM]":"153.5","Cell RNA - HDLM-2 [nTPM]":"529.0","Cell RNA - HEK 293 [nTPM]":"388.4","Cell RNA - HEL [nTPM]":"332.4","Cell RNA - HeLa [nTPM]":"385.3","Cell RNA - Hep G2 [nTPM]":"473.8","Cell RNA - HHSteC [nTPM]":"753.0","Cell RNA - HL-60 [nTPM]":"85.5","Cell RNA - HMC-1 [nTPM]":"267.1","Cell RNA - HSkMC [nTPM]":"754.5","Cell RNA - hTCEpi [nTPM]":"439.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"621.2","Cell RNA - hTERT-HME1 [nTPM]":"314.7","Cell RNA - hTERT-RPE1 [nTPM]":"389.3","Cell RNA - HUVEC TERT2 [nTPM]":"331.2","Cell RNA - JURKAT [nTPM]":"111.8","Cell RNA - K-562 [nTPM]":"276.9","Cell RNA - Karpas-707 [nTPM]":"681.1","Cell RNA - LHCN-M2 [nTPM]":"359.7","Cell RNA - MCF7 [nTPM]":"431.4","Cell RNA - MOLT-4 [nTPM]":"100.1","Cell RNA - NB-4 [nTPM]":"267.6","Cell RNA - NTERA-2 [nTPM]":"336.0","Cell RNA - OE19 [nTPM]":"1052.6","Cell RNA - PC-3 [nTPM]":"791.5","Cell RNA - REH [nTPM]":"169.7","Cell RNA - RH-30 [nTPM]":"80.5","Cell RNA - RPMI-8226 [nTPM]":"1472.0","Cell RNA - RPTEC TERT1 [nTPM]":"669.1","Cell RNA - RT4 [nTPM]":"2798.2","Cell RNA - SCLC-21H [nTPM]":"141.8","Cell RNA - SH-SY5Y [nTPM]":"121.6","Cell RNA - SiHa [nTPM]":"420.2","Cell RNA - SK-BR-3 [nTPM]":"229.2","Cell RNA - SK-MEL-30 [nTPM]":"928.8","Cell RNA - SuSa [nTPM]":"75.7","Cell RNA - T-47d [nTPM]":"210.4","Cell RNA - THP-1 [nTPM]":"214.0","Cell RNA - TIME [nTPM]":"426.3","Cell RNA - U-138 MG [nTPM]":"347.7","Cell RNA - U-2 OS [nTPM]":"162.7","Cell RNA - U-2197 [nTPM]":"305.5","Cell RNA - U-251 MG [nTPM]":"211.8","Cell RNA - U-266\/70 [nTPM]":"148.5","Cell RNA - U-266\/84 [nTPM]":"347.4","Cell RNA - U-698 [nTPM]":"251.1","Cell RNA - U-87 MG [nTPM]":"1432.5","Cell RNA - U-937 [nTPM]":"430.2","Cell RNA - WM-115 [nTPM]":"242.3","Blood RNA - basophil [nTPM]":"390.1","Blood RNA - classical monocyte [nTPM]":"505.5","Blood RNA - eosinophil [nTPM]":"313.1","Blood RNA - gdT-cell [nTPM]":"242.9","Blood RNA - intermediate monocyte [nTPM]":"840.3","Blood RNA - MAIT T-cell [nTPM]":"224.5","Blood RNA - memory B-cell [nTPM]":"198.5","Blood RNA - memory CD4 T-cell [nTPM]":"315.4","Blood RNA - memory CD8 T-cell [nTPM]":"255.4","Blood RNA - myeloid DC [nTPM]":"766.1","Blood RNA - naive B-cell [nTPM]":"172.7","Blood RNA - naive CD4 T-cell [nTPM]":"221.0","Blood RNA - naive CD8 T-cell [nTPM]":"217.6","Blood RNA - neutrophil [nTPM]":"445.6","Blood RNA - NK-cell [nTPM]":"152.4","Blood RNA - non-classical monocyte [nTPM]":"1322.9","Blood RNA - plasmacytoid DC [nTPM]":"93.4","Blood RNA - T-reg [nTPM]":"406.9","Blood RNA - total PBMC [nTPM]":"475.2","Brain RNA - amygdala [nTPM]":"254.1","Brain RNA - basal ganglia [nTPM]":"253.6","Brain RNA - cerebellum [nTPM]":"255.4","Brain RNA - cerebral cortex [nTPM]":"314.6","Brain RNA - hippocampal formation [nTPM]":"252.8","Brain RNA - hypothalamus [nTPM]":"263.0","Brain RNA - medulla oblongata [nTPM]":"258.4","Brain RNA - midbrain [nTPM]":"257.8","Brain RNA - pons [nTPM]":"259.6","Brain RNA - spinal cord [nTPM]":"257.5","Brain RNA - thalamus [nTPM]":"262.8","Brain RNA - white matter [nTPM]":"262.9","Single Cell Type RNA - Adipocytes [nTPM]":"210.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"176.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"298.4","Single Cell Type RNA - Astrocytes [nTPM]":"43.4","Single Cell Type RNA - B-cells [nTPM]":"140.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"385.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"460.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5910.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"191.2","Single Cell Type RNA - Bipolar cells [nTPM]":"69.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"317.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"345.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"105.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"268.8","Single Cell Type RNA - Club cells [nTPM]":"4352.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"415.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"310.4","Single Cell Type RNA - dendritic cells [nTPM]":"126.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"803.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"538.1","Single Cell Type RNA - Ductal cells [nTPM]":"588.4","Single Cell Type RNA - Early spermatids [nTPM]":"10.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"388.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"205.1","Single Cell Type RNA - Endothelial cells [nTPM]":"307.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"239.3","Single Cell Type RNA - Erythroid cells [nTPM]":"61.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"488.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1199.4","Single Cell Type RNA - Fibroblasts [nTPM]":"238.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"297.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"458.8","Single Cell Type RNA - granulocytes [nTPM]":"228.2","Single Cell Type RNA - Granulosa cells [nTPM]":"131.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"250.6","Single Cell Type RNA - Hepatocytes [nTPM]":"464.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"2827.7","Single Cell Type RNA - Horizontal cells [nTPM]":"67.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"308.6","Single Cell Type RNA - Ionocytes [nTPM]":"1462.8","Single Cell Type RNA - Kupffer cells [nTPM]":"483.4","Single Cell Type RNA - Langerhans cells [nTPM]":"1256.2","Single Cell Type RNA - Late spermatids [nTPM]":"40.8","Single Cell Type RNA - Leydig cells [nTPM]":"381.1","Single Cell Type RNA - Macrophages [nTPM]":"806.9","Single Cell Type RNA - Melanocytes [nTPM]":"471.4","Single Cell Type RNA - Microglial cells [nTPM]":"24.4","Single Cell Type RNA - monocytes [nTPM]":"915.9","Single Cell Type RNA - Muller glia cells [nTPM]":"160.6","Single Cell Type RNA - NK-cells [nTPM]":"255.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"32.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"810.9","Single Cell Type RNA - Paneth cells [nTPM]":"735.6","Single Cell Type RNA - Peritubular cells [nTPM]":"330.2","Single Cell Type RNA - Plasma cells [nTPM]":"167.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"674.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"524.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"469.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1997.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"72.9","Single Cell Type RNA - Sertoli cells [nTPM]":"118.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"86.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"320.0","Single Cell Type RNA - Spermatocytes [nTPM]":"33.7","Single Cell Type RNA - Spermatogonia [nTPM]":"111.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4910.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"596.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"402.5","Single Cell Type RNA - T-cells [nTPM]":"202.8","Single Cell Type RNA - Theca cells [nTPM]":"170.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"367.2","Single Cell Type RNA - Urothelial cells [nTPM]":"3198.3"},{"Gene":"CTDP1","Gene synonym":["FCP1"],"Ensembl":"ENSG00000060069","Gene description":"CTD phosphatase subunit 1","Uniprot":["Q9Y5B0"],"Chromosome":"18","Position":"79679803-79754510","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Mitosis"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":["Cataract","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"113.1","Late spermatids":"123.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"3.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB032641","HPA040394","HPA070389"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 65: Plasmacytoid DCs - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB032641":"AB_2261235","HPA040394":"AB_10794029","HPA070389":"AB_2732155"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.43e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.51e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.3","Tissue RNA - adrenal gland [nTPM]":"7.4","Tissue RNA - amygdala [nTPM]":"3.8","Tissue RNA - appendix [nTPM]":"7.2","Tissue RNA - basal ganglia [nTPM]":"3.9","Tissue RNA - bone marrow [nTPM]":"13.7","Tissue RNA - breast [nTPM]":"8.9","Tissue RNA - cerebellum [nTPM]":"3.3","Tissue RNA - cerebral cortex [nTPM]":"4.2","Tissue RNA - cervix [nTPM]":"7.8","Tissue RNA - choroid plexus [nTPM]":"4.1","Tissue RNA - colon [nTPM]":"11.1","Tissue RNA - duodenum [nTPM]":"7.2","Tissue RNA - endometrium 1 [nTPM]":"10.4","Tissue RNA - epididymis [nTPM]":"1.4","Tissue RNA - esophagus [nTPM]":"10.7","Tissue RNA - fallopian tube [nTPM]":"8.1","Tissue RNA - gallbladder [nTPM]":"4.0","Tissue RNA - heart muscle [nTPM]":"7.2","Tissue RNA - hippocampal formation [nTPM]":"3.3","Tissue RNA - hypothalamus [nTPM]":"3.3","Tissue RNA - kidney [nTPM]":"7.9","Tissue RNA - liver [nTPM]":"9.5","Tissue RNA - lung [nTPM]":"9.3","Tissue RNA - lymph node [nTPM]":"8.7","Tissue RNA - medulla oblongata [nTPM]":"5.3","Tissue RNA - midbrain [nTPM]":"4.2","Tissue RNA - ovary [nTPM]":"5.0","Tissue RNA - pancreas [nTPM]":"9.0","Tissue RNA - parathyroid gland [nTPM]":"3.3","Tissue RNA - pituitary gland [nTPM]":"6.9","Tissue RNA - placenta [nTPM]":"4.2","Tissue RNA - pons [nTPM]":"4.0","Tissue RNA - prostate [nTPM]":"8.2","Tissue RNA - rectum [nTPM]":"3.1","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"9.5","Tissue RNA - seminal vesicle [nTPM]":"3.9","Tissue RNA - skeletal muscle [nTPM]":"11.9","Tissue RNA - skin 1 [nTPM]":"20.5","Tissue RNA - small intestine [nTPM]":"10.9","Tissue RNA - smooth muscle [nTPM]":"3.1","Tissue RNA - spinal cord [nTPM]":"3.3","Tissue RNA - spleen [nTPM]":"13.5","Tissue RNA - stomach 1 [nTPM]":"9.9","Tissue RNA - testis [nTPM]":"22.2","Tissue RNA - thalamus [nTPM]":"4.0","Tissue RNA - thymus [nTPM]":"6.5","Tissue RNA - thyroid gland [nTPM]":"8.0","Tissue RNA - tongue [nTPM]":"3.1","Tissue RNA - tonsil [nTPM]":"3.7","Tissue RNA - urinary bladder [nTPM]":"9.6","Tissue RNA - vagina [nTPM]":"8.6","Tissue RNA - white matter [nTPM]":"4.4","Cell RNA - A-431 [nTPM]":"13.4","Cell RNA - A549 [nTPM]":"14.0","Cell RNA - AF22 [nTPM]":"7.7","Cell RNA - AN3-CA [nTPM]":"11.0","Cell RNA - ASC diff [nTPM]":"6.0","Cell RNA - ASC TERT1 [nTPM]":"5.0","Cell RNA - BEWO [nTPM]":"25.9","Cell RNA - BJ [nTPM]":"9.6","Cell RNA - BJ hTERT+ [nTPM]":"6.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.5","Cell RNA - CACO-2 [nTPM]":"9.4","Cell RNA - CAPAN-2 [nTPM]":"8.0","Cell RNA - Daudi [nTPM]":"17.2","Cell RNA - EFO-21 [nTPM]":"4.2","Cell RNA - fHDF\/TERT166 [nTPM]":"5.6","Cell RNA - GAMG [nTPM]":"9.1","Cell RNA - HaCaT [nTPM]":"16.4","Cell RNA - HAP1 [nTPM]":"6.6","Cell RNA - HBEC3-KT [nTPM]":"8.8","Cell RNA - HBF TERT88 [nTPM]":"3.1","Cell RNA - HDLM-2 [nTPM]":"16.9","Cell RNA - HEK 293 [nTPM]":"12.4","Cell RNA - HEL [nTPM]":"8.5","Cell RNA - HeLa [nTPM]":"6.6","Cell RNA - Hep G2 [nTPM]":"12.9","Cell RNA - HHSteC [nTPM]":"8.7","Cell RNA - HL-60 [nTPM]":"37.6","Cell RNA - HMC-1 [nTPM]":"20.5","Cell RNA - HSkMC [nTPM]":"8.4","Cell RNA - hTCEpi [nTPM]":"8.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.1","Cell RNA - hTERT-HME1 [nTPM]":"3.8","Cell RNA - hTERT-RPE1 [nTPM]":"4.6","Cell RNA - HUVEC TERT2 [nTPM]":"9.2","Cell RNA - JURKAT [nTPM]":"12.2","Cell RNA - K-562 [nTPM]":"11.2","Cell RNA - Karpas-707 [nTPM]":"8.1","Cell RNA - LHCN-M2 [nTPM]":"3.0","Cell RNA - MCF7 [nTPM]":"11.5","Cell RNA - MOLT-4 [nTPM]":"25.4","Cell RNA - NB-4 [nTPM]":"29.5","Cell RNA - NTERA-2 [nTPM]":"12.7","Cell RNA - OE19 [nTPM]":"4.2","Cell RNA - PC-3 [nTPM]":"19.1","Cell RNA - REH [nTPM]":"20.7","Cell RNA - RH-30 [nTPM]":"10.1","Cell RNA - RPMI-8226 [nTPM]":"20.0","Cell RNA - RPTEC TERT1 [nTPM]":"5.6","Cell RNA - RT4 [nTPM]":"13.1","Cell RNA - SCLC-21H [nTPM]":"12.0","Cell RNA - SH-SY5Y [nTPM]":"12.4","Cell RNA - SiHa [nTPM]":"10.2","Cell RNA - SK-BR-3 [nTPM]":"9.8","Cell RNA - SK-MEL-30 [nTPM]":"13.9","Cell RNA - SuSa [nTPM]":"5.8","Cell RNA - T-47d [nTPM]":"8.0","Cell RNA - THP-1 [nTPM]":"21.7","Cell RNA - TIME [nTPM]":"12.9","Cell RNA - U-138 MG [nTPM]":"12.9","Cell RNA - U-2 OS [nTPM]":"19.4","Cell RNA - U-2197 [nTPM]":"5.3","Cell RNA - U-251 MG [nTPM]":"9.7","Cell RNA - U-266\/70 [nTPM]":"7.4","Cell RNA - U-266\/84 [nTPM]":"27.6","Cell RNA - U-698 [nTPM]":"16.1","Cell RNA - U-87 MG [nTPM]":"11.0","Cell RNA - U-937 [nTPM]":"18.8","Cell RNA - WM-115 [nTPM]":"9.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"3.2","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"3.8","Brain RNA - basal ganglia [nTPM]":"3.9","Brain RNA - cerebellum [nTPM]":"3.3","Brain RNA - cerebral cortex [nTPM]":"4.2","Brain RNA - hippocampal formation [nTPM]":"3.3","Brain RNA - hypothalamus [nTPM]":"3.3","Brain RNA - medulla oblongata [nTPM]":"5.3","Brain RNA - midbrain [nTPM]":"4.2","Brain RNA - pons [nTPM]":"4.0","Brain RNA - spinal cord [nTPM]":"3.3","Brain RNA - thalamus [nTPM]":"4.0","Brain RNA - white matter [nTPM]":"4.4","Single Cell Type RNA - Adipocytes [nTPM]":"7.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.1","Single Cell Type RNA - Astrocytes [nTPM]":"3.6","Single Cell Type RNA - B-cells [nTPM]":"9.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"9.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"4.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.8","Single Cell Type RNA - dendritic cells [nTPM]":"24.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"20.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.4","Single Cell Type RNA - Early spermatids [nTPM]":"113.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.0","Single Cell Type RNA - Endothelial cells [nTPM]":"7.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"13.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.0","Single Cell Type RNA - Fibroblasts [nTPM]":"4.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.0","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"7.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"5.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.8","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.6","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"7.5","Single Cell Type RNA - Langerhans cells [nTPM]":"9.5","Single Cell Type RNA - Late spermatids [nTPM]":"123.2","Single Cell Type RNA - Leydig cells [nTPM]":"7.8","Single Cell Type RNA - Macrophages [nTPM]":"13.8","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"6.5","Single Cell Type RNA - Muller glia cells [nTPM]":"6.5","Single Cell Type RNA - NK-cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.2","Single Cell Type RNA - Paneth cells [nTPM]":"14.9","Single Cell Type RNA - Peritubular cells [nTPM]":"10.5","Single Cell Type RNA - Plasma cells [nTPM]":"15.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.4","Single Cell Type RNA - Spermatocytes [nTPM]":"18.0","Single Cell Type RNA - Spermatogonia [nTPM]":"10.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"19.0","Single Cell Type RNA - T-cells [nTPM]":"18.3","Single Cell Type RNA - Theca cells [nTPM]":"8.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.7","Single Cell Type RNA - Urothelial cells [nTPM]":"12.6"},{"Gene":"CTH","Gene synonym":[],"Ensembl":"ENSG00000116761","Gene description":"Cystathionine gamma-lyase","Uniprot":["P32929"],"Chromosome":"1","Position":"70411218-70439851","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Amino-acid biosynthesis","Cysteine biosynthesis"],"Molecular function":["Calmodulin-binding","Lyase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"liver":"122.9","ovary":"34.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"38.0","Hepatocytes":"141.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"liver cancer":"30.0","testis cancer":"8.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HHSteC":"39.7","Karpas-707":"63.8","SK-MEL-30":"85.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021591","HPA023300"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"220000","Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA021591":"AB_1847321","HPA023300":"AB_1847322"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.69e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Tissue RNA - adipose tissue [nTPM]":"4.3","Tissue RNA - adrenal gland [nTPM]":"12.9","Tissue RNA - amygdala [nTPM]":"3.4","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"3.1","Tissue RNA - bone marrow [nTPM]":"3.4","Tissue RNA - breast [nTPM]":"2.9","Tissue RNA - cerebellum [nTPM]":"3.3","Tissue RNA - cerebral cortex [nTPM]":"4.0","Tissue RNA - cervix [nTPM]":"2.5","Tissue RNA - choroid plexus [nTPM]":"4.5","Tissue RNA - colon [nTPM]":"5.1","Tissue RNA - duodenum [nTPM]":"5.2","Tissue RNA - endometrium 1 [nTPM]":"2.2","Tissue RNA - epididymis [nTPM]":"1.6","Tissue RNA - esophagus [nTPM]":"4.5","Tissue RNA - fallopian tube [nTPM]":"3.8","Tissue RNA - gallbladder [nTPM]":"1.8","Tissue RNA - heart muscle [nTPM]":"2.4","Tissue RNA - hippocampal formation [nTPM]":"3.3","Tissue RNA - hypothalamus [nTPM]":"3.6","Tissue RNA - kidney [nTPM]":"13.5","Tissue RNA - liver [nTPM]":"122.9","Tissue RNA - lung [nTPM]":"3.1","Tissue RNA - lymph node [nTPM]":"0.9","Tissue RNA - medulla oblongata [nTPM]":"3.4","Tissue RNA - midbrain [nTPM]":"3.7","Tissue RNA - ovary [nTPM]":"34.4","Tissue RNA - pancreas [nTPM]":"17.0","Tissue RNA - parathyroid gland [nTPM]":"1.4","Tissue RNA - pituitary gland [nTPM]":"2.9","Tissue RNA - placenta [nTPM]":"1.1","Tissue RNA - pons [nTPM]":"3.4","Tissue RNA - prostate [nTPM]":"4.3","Tissue RNA - rectum [nTPM]":"6.2","Tissue RNA - retina [nTPM]":"8.1","Tissue RNA - salivary gland [nTPM]":"2.5","Tissue RNA - seminal vesicle [nTPM]":"2.1","Tissue RNA - skeletal muscle [nTPM]":"3.6","Tissue RNA - skin 1 [nTPM]":"1.2","Tissue RNA - small intestine [nTPM]":"5.3","Tissue RNA - smooth muscle [nTPM]":"1.3","Tissue RNA - spinal cord [nTPM]":"2.7","Tissue RNA - spleen [nTPM]":"1.0","Tissue RNA - stomach 1 [nTPM]":"7.4","Tissue RNA - testis [nTPM]":"4.1","Tissue RNA - thalamus [nTPM]":"3.7","Tissue RNA - thymus [nTPM]":"0.6","Tissue RNA - thyroid gland [nTPM]":"7.7","Tissue RNA - tongue [nTPM]":"2.9","Tissue RNA - tonsil [nTPM]":"1.3","Tissue RNA - urinary bladder [nTPM]":"2.2","Tissue RNA - vagina [nTPM]":"1.9","Tissue RNA - white matter [nTPM]":"3.2","Cell RNA - A-431 [nTPM]":"10.2","Cell RNA - A549 [nTPM]":"1.5","Cell RNA - AF22 [nTPM]":"7.1","Cell RNA - AN3-CA [nTPM]":"10.0","Cell RNA - ASC diff [nTPM]":"8.5","Cell RNA - ASC TERT1 [nTPM]":"4.8","Cell RNA - BEWO [nTPM]":"15.0","Cell RNA - BJ [nTPM]":"4.3","Cell RNA - BJ hTERT+ [nTPM]":"4.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.7","Cell RNA - CACO-2 [nTPM]":"3.2","Cell RNA - CAPAN-2 [nTPM]":"6.4","Cell RNA - Daudi [nTPM]":"5.8","Cell RNA - EFO-21 [nTPM]":"3.4","Cell RNA - fHDF\/TERT166 [nTPM]":"3.1","Cell RNA - GAMG [nTPM]":"9.3","Cell RNA - HaCaT [nTPM]":"4.9","Cell RNA - HAP1 [nTPM]":"27.3","Cell RNA - HBEC3-KT [nTPM]":"3.1","Cell RNA - HBF TERT88 [nTPM]":"7.2","Cell RNA - HDLM-2 [nTPM]":"17.3","Cell RNA - HEK 293 [nTPM]":"5.9","Cell RNA - HEL [nTPM]":"7.0","Cell RNA - HeLa [nTPM]":"5.1","Cell RNA - Hep G2 [nTPM]":"9.4","Cell RNA - HHSteC [nTPM]":"39.7","Cell RNA - HL-60 [nTPM]":"7.8","Cell RNA - HMC-1 [nTPM]":"1.7","Cell RNA - HSkMC [nTPM]":"7.5","Cell RNA - hTCEpi [nTPM]":"24.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.5","Cell RNA - hTERT-HME1 [nTPM]":"8.8","Cell RNA - hTERT-RPE1 [nTPM]":"1.5","Cell RNA - HUVEC TERT2 [nTPM]":"3.2","Cell RNA - JURKAT [nTPM]":"11.9","Cell RNA - K-562 [nTPM]":"14.0","Cell RNA - Karpas-707 [nTPM]":"63.8","Cell RNA - LHCN-M2 [nTPM]":"2.2","Cell RNA - MCF7 [nTPM]":"3.2","Cell RNA - MOLT-4 [nTPM]":"2.7","Cell RNA - NB-4 [nTPM]":"1.9","Cell RNA - NTERA-2 [nTPM]":"7.2","Cell RNA - OE19 [nTPM]":"4.2","Cell RNA - PC-3 [nTPM]":"5.9","Cell RNA - REH [nTPM]":"3.0","Cell RNA - RH-30 [nTPM]":"3.7","Cell RNA - RPMI-8226 [nTPM]":"16.2","Cell RNA - RPTEC TERT1 [nTPM]":"7.3","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"3.9","Cell RNA - SH-SY5Y [nTPM]":"3.3","Cell RNA - SiHa [nTPM]":"6.6","Cell RNA - SK-BR-3 [nTPM]":"7.7","Cell RNA - SK-MEL-30 [nTPM]":"85.7","Cell RNA - SuSa [nTPM]":"13.3","Cell RNA - T-47d [nTPM]":"2.6","Cell RNA - THP-1 [nTPM]":"4.6","Cell RNA - TIME [nTPM]":"1.1","Cell RNA - U-138 MG [nTPM]":"1.2","Cell RNA - U-2 OS [nTPM]":"7.7","Cell RNA - U-2197 [nTPM]":"5.7","Cell RNA - U-251 MG [nTPM]":"4.1","Cell RNA - U-266\/70 [nTPM]":"23.8","Cell RNA - U-266\/84 [nTPM]":"15.3","Cell RNA - U-698 [nTPM]":"3.1","Cell RNA - U-87 MG [nTPM]":"9.8","Cell RNA - U-937 [nTPM]":"16.1","Cell RNA - WM-115 [nTPM]":"3.1","Blood RNA - basophil [nTPM]":"0.8","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"1.2","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"2.1","Blood RNA - memory B-cell [nTPM]":"2.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"1.7","Blood RNA - naive CD4 T-cell [nTPM]":"3.2","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"3.4","Brain RNA - basal ganglia [nTPM]":"3.1","Brain RNA - cerebellum [nTPM]":"3.3","Brain RNA - cerebral cortex [nTPM]":"4.0","Brain RNA - hippocampal formation [nTPM]":"3.3","Brain RNA - hypothalamus [nTPM]":"3.6","Brain RNA - medulla oblongata [nTPM]":"3.4","Brain RNA - midbrain [nTPM]":"3.7","Brain RNA - pons [nTPM]":"3.4","Brain RNA - spinal cord [nTPM]":"2.7","Brain RNA - thalamus [nTPM]":"3.7","Brain RNA - white matter [nTPM]":"3.2","Single Cell Type RNA - Adipocytes [nTPM]":"2.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.6","Single Cell Type RNA - Astrocytes [nTPM]":"16.6","Single Cell Type RNA - B-cells [nTPM]":"6.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"9.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"2.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - dendritic cells [nTPM]":"5.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"1.8","Single Cell Type RNA - Early spermatids [nTPM]":"27.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"38.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.4","Single Cell Type RNA - Endothelial cells [nTPM]":"3.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.8","Single Cell Type RNA - Fibroblasts [nTPM]":"13.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"141.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.9","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.5","Single Cell Type RNA - Langerhans cells [nTPM]":"5.7","Single Cell Type RNA - Late spermatids [nTPM]":"5.2","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"4.7","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.4","Single Cell Type RNA - Paneth cells [nTPM]":"12.9","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"10.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"29.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.7","Single Cell Type RNA - Spermatocytes [nTPM]":"1.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"11.2","Single Cell Type RNA - Theca cells [nTPM]":"4.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.1","Single Cell Type RNA - Urothelial cells [nTPM]":"3.8"},{"Gene":"CTNND1","Gene synonym":["CTNND","KIAA0384","p120","p120cas","p120ctn"],"Ensembl":"ENSG00000198561","Gene description":"Catenin delta 1","Uniprot":["O60716"],"Chromosome":"11","Position":"57753243-57819546","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Cell adhesion","Transcription","Transcription regulation","Wnt signaling pathway"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Ectodermal dysplasia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"305.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"4.9","intermediate monocyte":"9.5","myeloid DC":"6.3","non-classical monocyte":"5.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"dendritic cells":"6.3","monocytes":"9.5"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003837","HPA015954","HPA015955"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"200000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 61: Squamous epithelial cells - Keratinization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB003837":"AB_562066","HPA015954":"AB_2669326","HPA015955":"AB_1846068"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.02e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.54e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.33e-2"},"Tissue RNA - adipose tissue [nTPM]":"72.6","Tissue RNA - adrenal gland [nTPM]":"48.8","Tissue RNA - amygdala [nTPM]":"29.6","Tissue RNA - appendix [nTPM]":"34.8","Tissue RNA - basal ganglia [nTPM]":"28.1","Tissue RNA - bone marrow [nTPM]":"5.9","Tissue RNA - breast [nTPM]":"83.3","Tissue RNA - cerebellum [nTPM]":"28.2","Tissue RNA - cerebral cortex [nTPM]":"33.0","Tissue RNA - cervix [nTPM]":"86.0","Tissue RNA - choroid plexus [nTPM]":"50.0","Tissue RNA - colon [nTPM]":"107.9","Tissue RNA - duodenum [nTPM]":"97.8","Tissue RNA - endometrium 1 [nTPM]":"70.8","Tissue RNA - epididymis [nTPM]":"49.3","Tissue RNA - esophagus [nTPM]":"209.7","Tissue RNA - fallopian tube [nTPM]":"58.4","Tissue RNA - gallbladder [nTPM]":"56.3","Tissue RNA - heart muscle [nTPM]":"49.0","Tissue RNA - hippocampal formation [nTPM]":"26.6","Tissue RNA - hypothalamus [nTPM]":"26.8","Tissue RNA - kidney [nTPM]":"77.9","Tissue RNA - liver [nTPM]":"82.6","Tissue RNA - lung [nTPM]":"83.9","Tissue RNA - lymph node [nTPM]":"19.0","Tissue RNA - medulla oblongata [nTPM]":"34.8","Tissue RNA - midbrain [nTPM]":"30.6","Tissue RNA - ovary [nTPM]":"49.3","Tissue RNA - pancreas [nTPM]":"120.0","Tissue RNA - parathyroid gland [nTPM]":"76.1","Tissue RNA - pituitary gland [nTPM]":"57.7","Tissue RNA - placenta [nTPM]":"106.0","Tissue RNA - pons [nTPM]":"32.5","Tissue RNA - prostate [nTPM]":"78.9","Tissue RNA - rectum [nTPM]":"102.0","Tissue RNA - retina [nTPM]":"23.5","Tissue RNA - salivary gland [nTPM]":"121.8","Tissue RNA - seminal vesicle [nTPM]":"57.1","Tissue RNA - skeletal muscle [nTPM]":"26.8","Tissue RNA - skin 1 [nTPM]":"129.4","Tissue RNA - small intestine [nTPM]":"104.9","Tissue RNA - smooth muscle [nTPM]":"54.8","Tissue RNA - spinal cord [nTPM]":"32.3","Tissue RNA - spleen [nTPM]":"51.5","Tissue RNA - stomach 1 [nTPM]":"105.4","Tissue RNA - testis [nTPM]":"44.3","Tissue RNA - thalamus [nTPM]":"38.0","Tissue RNA - thymus [nTPM]":"24.4","Tissue RNA - thyroid gland [nTPM]":"98.6","Tissue RNA - tongue [nTPM]":"19.9","Tissue RNA - tonsil [nTPM]":"48.4","Tissue RNA - urinary bladder [nTPM]":"83.5","Tissue RNA - vagina [nTPM]":"111.9","Tissue RNA - white matter [nTPM]":"33.5","Cell RNA - A-431 [nTPM]":"156.6","Cell RNA - A549 [nTPM]":"106.4","Cell RNA - AF22 [nTPM]":"70.2","Cell RNA - AN3-CA [nTPM]":"63.3","Cell RNA - ASC diff [nTPM]":"46.1","Cell RNA - ASC TERT1 [nTPM]":"71.6","Cell RNA - BEWO [nTPM]":"141.7","Cell RNA - BJ [nTPM]":"65.1","Cell RNA - BJ hTERT+ [nTPM]":"78.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"58.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"55.6","Cell RNA - CACO-2 [nTPM]":"88.5","Cell RNA - CAPAN-2 [nTPM]":"163.9","Cell RNA - Daudi [nTPM]":"1.0","Cell RNA - EFO-21 [nTPM]":"113.2","Cell RNA - fHDF\/TERT166 [nTPM]":"72.5","Cell RNA - GAMG [nTPM]":"50.9","Cell RNA - HaCaT [nTPM]":"201.7","Cell RNA - HAP1 [nTPM]":"58.8","Cell RNA - HBEC3-KT [nTPM]":"97.4","Cell RNA - HBF TERT88 [nTPM]":"71.1","Cell RNA - HDLM-2 [nTPM]":"1.0","Cell RNA - HEK 293 [nTPM]":"21.9","Cell RNA - HEL [nTPM]":"32.0","Cell RNA - HeLa [nTPM]":"35.8","Cell RNA - Hep G2 [nTPM]":"109.9","Cell RNA - HHSteC [nTPM]":"52.6","Cell RNA - HL-60 [nTPM]":"5.0","Cell RNA - HMC-1 [nTPM]":"52.7","Cell RNA - HSkMC [nTPM]":"70.0","Cell RNA - hTCEpi [nTPM]":"133.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"67.1","Cell RNA - hTERT-HME1 [nTPM]":"73.5","Cell RNA - hTERT-RPE1 [nTPM]":"103.8","Cell RNA - HUVEC TERT2 [nTPM]":"197.2","Cell RNA - JURKAT [nTPM]":"1.7","Cell RNA - K-562 [nTPM]":"55.1","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"55.1","Cell RNA - MCF7 [nTPM]":"48.0","Cell RNA - MOLT-4 [nTPM]":"1.7","Cell RNA - NB-4 [nTPM]":"13.9","Cell RNA - NTERA-2 [nTPM]":"54.7","Cell RNA - OE19 [nTPM]":"101.2","Cell RNA - PC-3 [nTPM]":"56.5","Cell RNA - REH [nTPM]":"0.7","Cell RNA - RH-30 [nTPM]":"67.4","Cell RNA - RPMI-8226 [nTPM]":"1.3","Cell RNA - RPTEC TERT1 [nTPM]":"90.2","Cell RNA - RT4 [nTPM]":"171.0","Cell RNA - SCLC-21H [nTPM]":"4.9","Cell RNA - SH-SY5Y [nTPM]":"40.1","Cell RNA - SiHa [nTPM]":"91.5","Cell RNA - SK-BR-3 [nTPM]":"133.6","Cell RNA - SK-MEL-30 [nTPM]":"113.1","Cell RNA - SuSa [nTPM]":"176.3","Cell RNA - T-47d [nTPM]":"138.9","Cell RNA - THP-1 [nTPM]":"6.1","Cell RNA - TIME [nTPM]":"166.0","Cell RNA - U-138 MG [nTPM]":"59.6","Cell RNA - U-2 OS [nTPM]":"50.3","Cell RNA - U-2197 [nTPM]":"53.2","Cell RNA - U-251 MG [nTPM]":"34.6","Cell RNA - U-266\/70 [nTPM]":"1.2","Cell RNA - U-266\/84 [nTPM]":"0.9","Cell RNA - U-698 [nTPM]":"2.3","Cell RNA - U-87 MG [nTPM]":"53.2","Cell RNA - U-937 [nTPM]":"3.4","Cell RNA - WM-115 [nTPM]":"111.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"4.9","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"9.5","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"6.3","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"5.6","Blood RNA - plasmacytoid DC [nTPM]":"1.4","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"29.6","Brain RNA - basal ganglia [nTPM]":"28.1","Brain RNA - cerebellum [nTPM]":"28.2","Brain RNA - cerebral cortex [nTPM]":"33.0","Brain RNA - hippocampal formation [nTPM]":"26.6","Brain RNA - hypothalamus [nTPM]":"26.8","Brain RNA - medulla oblongata [nTPM]":"34.8","Brain RNA - midbrain [nTPM]":"30.6","Brain RNA - pons [nTPM]":"32.5","Brain RNA - spinal cord [nTPM]":"32.3","Brain RNA - thalamus [nTPM]":"38.0","Brain RNA - white matter [nTPM]":"33.5","Single Cell Type RNA - Adipocytes [nTPM]":"116.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"147.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"84.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"8.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"117.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"96.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"82.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"126.9","Single Cell Type RNA - Bipolar cells [nTPM]":"21.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"101.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"70.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"125.8","Single Cell Type RNA - Club cells [nTPM]":"96.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"141.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"94.0","Single Cell Type RNA - dendritic cells [nTPM]":"2.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"305.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"106.7","Single Cell Type RNA - Early spermatids [nTPM]":"14.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"91.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"58.5","Single Cell Type RNA - Endothelial cells [nTPM]":"98.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"86.2","Single Cell Type RNA - Erythroid cells [nTPM]":"21.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"97.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"85.6","Single Cell Type RNA - Fibroblasts [nTPM]":"34.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"165.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"139.4","Single Cell Type RNA - granulocytes [nTPM]":"32.4","Single Cell Type RNA - Granulosa cells [nTPM]":"61.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"91.8","Single Cell Type RNA - Hepatocytes [nTPM]":"127.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"44.4","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"160.7","Single Cell Type RNA - Ionocytes [nTPM]":"52.9","Single Cell Type RNA - Kupffer cells [nTPM]":"64.3","Single Cell Type RNA - Langerhans cells [nTPM]":"55.5","Single Cell Type RNA - Late spermatids [nTPM]":"10.5","Single Cell Type RNA - Leydig cells [nTPM]":"28.3","Single Cell Type RNA - Macrophages [nTPM]":"46.4","Single Cell Type RNA - Melanocytes [nTPM]":"48.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"28.5","Single Cell Type RNA - Muller glia cells [nTPM]":"30.2","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"141.8","Single Cell Type RNA - Paneth cells [nTPM]":"169.3","Single Cell Type RNA - Peritubular cells [nTPM]":"38.4","Single Cell Type RNA - Plasma cells [nTPM]":"5.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"116.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"179.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"57.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"88.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"26.4","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"32.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"38.1","Single Cell Type RNA - Spermatocytes [nTPM]":"37.0","Single Cell Type RNA - Spermatogonia [nTPM]":"21.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"285.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"200.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"90.8","Single Cell Type RNA - T-cells [nTPM]":"6.2","Single Cell Type RNA - Theca cells [nTPM]":"39.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"127.0","Single Cell Type RNA - Urothelial cells [nTPM]":"194.6"},{"Gene":"CTNS","Gene synonym":["CTNS-LSB","PQLC4","SLC66A4"],"Ensembl":"ENSG00000040531","Gene description":"Cystinosin, lysosomal cystine transporter","Uniprot":["O60931"],"Chromosome":"17","Position":"3636459-3663103","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Melanin biosynthesis","Protein transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"35.5","Late spermatids":"29.3","Theca cells":"30.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"34.3","granulocytes":"27.9","monocytes":"10.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"144.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046947"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Intermediate filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Vesicles","Intermediate filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA046947":"AB_2679872"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.33e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.39e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.3","Tissue RNA - adrenal gland [nTPM]":"19.5","Tissue RNA - amygdala [nTPM]":"9.5","Tissue RNA - appendix [nTPM]":"10.0","Tissue RNA - basal ganglia [nTPM]":"17.0","Tissue RNA - bone marrow [nTPM]":"10.2","Tissue RNA - breast [nTPM]":"9.6","Tissue RNA - cerebellum [nTPM]":"13.5","Tissue RNA - cerebral cortex [nTPM]":"12.1","Tissue RNA - cervix [nTPM]":"20.3","Tissue RNA - choroid plexus [nTPM]":"12.1","Tissue RNA - colon [nTPM]":"8.3","Tissue RNA - duodenum [nTPM]":"12.2","Tissue RNA - endometrium 1 [nTPM]":"11.3","Tissue RNA - epididymis [nTPM]":"6.4","Tissue RNA - esophagus [nTPM]":"8.7","Tissue RNA - fallopian tube [nTPM]":"10.3","Tissue RNA - gallbladder [nTPM]":"13.1","Tissue RNA - heart muscle [nTPM]":"10.5","Tissue RNA - hippocampal formation [nTPM]":"10.8","Tissue RNA - hypothalamus [nTPM]":"10.3","Tissue RNA - kidney [nTPM]":"15.2","Tissue RNA - liver [nTPM]":"15.9","Tissue RNA - lung [nTPM]":"11.6","Tissue RNA - lymph node [nTPM]":"10.0","Tissue RNA - medulla oblongata [nTPM]":"16.5","Tissue RNA - midbrain [nTPM]":"16.8","Tissue RNA - ovary [nTPM]":"12.1","Tissue RNA - pancreas [nTPM]":"27.0","Tissue RNA - parathyroid gland [nTPM]":"13.6","Tissue RNA - pituitary gland [nTPM]":"9.6","Tissue RNA - placenta [nTPM]":"12.9","Tissue RNA - pons [nTPM]":"18.0","Tissue RNA - prostate [nTPM]":"10.8","Tissue RNA - rectum [nTPM]":"7.2","Tissue RNA - retina [nTPM]":"6.8","Tissue RNA - salivary gland [nTPM]":"12.0","Tissue RNA - seminal vesicle [nTPM]":"11.6","Tissue RNA - skeletal muscle [nTPM]":"15.3","Tissue RNA - skin 1 [nTPM]":"19.2","Tissue RNA - small intestine [nTPM]":"11.0","Tissue RNA - smooth muscle [nTPM]":"8.6","Tissue RNA - spinal cord [nTPM]":"10.9","Tissue RNA - spleen [nTPM]":"12.1","Tissue RNA - stomach 1 [nTPM]":"15.0","Tissue RNA - testis [nTPM]":"24.8","Tissue RNA - thalamus [nTPM]":"13.2","Tissue RNA - thymus [nTPM]":"8.8","Tissue RNA - thyroid gland [nTPM]":"9.2","Tissue RNA - tongue [nTPM]":"7.4","Tissue RNA - tonsil [nTPM]":"9.5","Tissue RNA - urinary bladder [nTPM]":"9.1","Tissue RNA - vagina [nTPM]":"9.4","Tissue RNA - white matter [nTPM]":"28.0","Cell RNA - A-431 [nTPM]":"17.6","Cell RNA - A549 [nTPM]":"37.0","Cell RNA - AF22 [nTPM]":"22.6","Cell RNA - AN3-CA [nTPM]":"18.2","Cell RNA - ASC diff [nTPM]":"34.5","Cell RNA - ASC TERT1 [nTPM]":"16.9","Cell RNA - BEWO [nTPM]":"13.0","Cell RNA - BJ [nTPM]":"19.6","Cell RNA - BJ hTERT+ [nTPM]":"28.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"26.0","Cell RNA - CACO-2 [nTPM]":"21.0","Cell RNA - CAPAN-2 [nTPM]":"16.0","Cell RNA - Daudi [nTPM]":"10.2","Cell RNA - EFO-21 [nTPM]":"17.8","Cell RNA - fHDF\/TERT166 [nTPM]":"11.6","Cell RNA - GAMG [nTPM]":"55.9","Cell RNA - HaCaT [nTPM]":"40.1","Cell RNA - HAP1 [nTPM]":"19.8","Cell RNA - HBEC3-KT [nTPM]":"12.1","Cell RNA - HBF TERT88 [nTPM]":"12.6","Cell RNA - HDLM-2 [nTPM]":"144.3","Cell RNA - HEK 293 [nTPM]":"33.7","Cell RNA - HEL [nTPM]":"10.8","Cell RNA - HeLa [nTPM]":"32.2","Cell RNA - Hep G2 [nTPM]":"19.3","Cell RNA - HHSteC [nTPM]":"46.5","Cell RNA - HL-60 [nTPM]":"8.0","Cell RNA - HMC-1 [nTPM]":"81.3","Cell RNA - HSkMC [nTPM]":"23.8","Cell RNA - hTCEpi [nTPM]":"14.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.2","Cell RNA - hTERT-HME1 [nTPM]":"15.4","Cell RNA - hTERT-RPE1 [nTPM]":"28.1","Cell RNA - HUVEC TERT2 [nTPM]":"22.2","Cell RNA - JURKAT [nTPM]":"18.7","Cell RNA - K-562 [nTPM]":"12.6","Cell RNA - Karpas-707 [nTPM]":"15.9","Cell RNA - LHCN-M2 [nTPM]":"16.6","Cell RNA - MCF7 [nTPM]":"15.1","Cell RNA - MOLT-4 [nTPM]":"7.8","Cell RNA - NB-4 [nTPM]":"7.9","Cell RNA - NTERA-2 [nTPM]":"9.8","Cell RNA - OE19 [nTPM]":"12.2","Cell RNA - PC-3 [nTPM]":"16.8","Cell RNA - REH [nTPM]":"16.4","Cell RNA - RH-30 [nTPM]":"9.3","Cell RNA - RPMI-8226 [nTPM]":"23.0","Cell RNA - RPTEC TERT1 [nTPM]":"15.3","Cell RNA - RT4 [nTPM]":"16.2","Cell RNA - SCLC-21H [nTPM]":"3.9","Cell RNA - SH-SY5Y [nTPM]":"17.2","Cell RNA - SiHa [nTPM]":"19.2","Cell RNA - SK-BR-3 [nTPM]":"24.4","Cell RNA - SK-MEL-30 [nTPM]":"20.3","Cell RNA - SuSa [nTPM]":"19.0","Cell RNA - T-47d [nTPM]":"17.1","Cell RNA - THP-1 [nTPM]":"7.7","Cell RNA - TIME [nTPM]":"24.2","Cell RNA - U-138 MG [nTPM]":"17.2","Cell RNA - U-2 OS [nTPM]":"11.6","Cell RNA - U-2197 [nTPM]":"40.3","Cell RNA - U-251 MG [nTPM]":"13.3","Cell RNA - U-266\/70 [nTPM]":"12.4","Cell RNA - U-266\/84 [nTPM]":"20.0","Cell RNA - U-698 [nTPM]":"4.2","Cell RNA - U-87 MG [nTPM]":"28.1","Cell RNA - U-937 [nTPM]":"7.8","Cell RNA - WM-115 [nTPM]":"11.8","Blood RNA - basophil [nTPM]":"27.9","Blood RNA - classical monocyte [nTPM]":"10.4","Blood RNA - eosinophil [nTPM]":"21.8","Blood RNA - gdT-cell [nTPM]":"3.0","Blood RNA - intermediate monocyte [nTPM]":"6.9","Blood RNA - MAIT T-cell [nTPM]":"4.9","Blood RNA - memory B-cell [nTPM]":"5.8","Blood RNA - memory CD4 T-cell [nTPM]":"4.0","Blood RNA - memory CD8 T-cell [nTPM]":"5.7","Blood RNA - myeloid DC [nTPM]":"9.7","Blood RNA - naive B-cell [nTPM]":"4.9","Blood RNA - naive CD4 T-cell [nTPM]":"4.5","Blood RNA - naive CD8 T-cell [nTPM]":"5.5","Blood RNA - neutrophil [nTPM]":"3.1","Blood RNA - NK-cell [nTPM]":"5.2","Blood RNA - non-classical monocyte [nTPM]":"7.1","Blood RNA - plasmacytoid DC [nTPM]":"34.3","Blood RNA - T-reg [nTPM]":"4.3","Blood RNA - total PBMC [nTPM]":"7.3","Brain RNA - amygdala [nTPM]":"9.5","Brain RNA - basal ganglia [nTPM]":"17.0","Brain RNA - cerebellum [nTPM]":"13.5","Brain RNA - cerebral cortex [nTPM]":"12.1","Brain RNA - hippocampal formation [nTPM]":"10.8","Brain RNA - hypothalamus [nTPM]":"10.3","Brain RNA - medulla oblongata [nTPM]":"16.5","Brain RNA - midbrain [nTPM]":"16.8","Brain RNA - pons [nTPM]":"18.0","Brain RNA - spinal cord [nTPM]":"10.9","Brain RNA - thalamus [nTPM]":"13.2","Brain RNA - white matter [nTPM]":"28.0","Single Cell Type RNA - Adipocytes [nTPM]":"4.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.2","Single Cell Type RNA - Astrocytes [nTPM]":"6.5","Single Cell Type RNA - B-cells [nTPM]":"4.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"2.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.1","Single Cell Type RNA - dendritic cells [nTPM]":"5.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.7","Single Cell Type RNA - Early spermatids [nTPM]":"35.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.4","Single Cell Type RNA - Endothelial cells [nTPM]":"5.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"4.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.1","Single Cell Type RNA - Fibroblasts [nTPM]":"6.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.3","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"6.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.3","Single Cell Type RNA - Hepatocytes [nTPM]":"7.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.2","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.5","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"7.2","Single Cell Type RNA - Langerhans cells [nTPM]":"5.9","Single Cell Type RNA - Late spermatids [nTPM]":"29.3","Single Cell Type RNA - Leydig cells [nTPM]":"9.6","Single Cell Type RNA - Macrophages [nTPM]":"12.1","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"10.0","Single Cell Type RNA - Muller glia cells [nTPM]":"6.5","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.4","Single Cell Type RNA - Paneth cells [nTPM]":"3.3","Single Cell Type RNA - Peritubular cells [nTPM]":"12.8","Single Cell Type RNA - Plasma cells [nTPM]":"4.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.5","Single Cell Type RNA - Spermatocytes [nTPM]":"19.7","Single Cell Type RNA - Spermatogonia [nTPM]":"8.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.5","Single Cell Type RNA - T-cells [nTPM]":"3.3","Single Cell Type RNA - Theca cells [nTPM]":"30.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.8","Single Cell Type RNA - Urothelial cells [nTPM]":"3.2"},{"Gene":"CTPS1","Gene synonym":["CTPS","GATD5"],"Ensembl":"ENSG00000171793","Gene description":"CTP synthase 1","Uniprot":["P17812"],"Chromosome":"1","Position":"40979688-41012565","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Immunity","Pyrimidine biosynthesis"],"Molecular function":["Ligase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"73.4"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017111","HPA051322"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"150000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Actin filaments"],"Antibody RRID":{"CAB017111":null,"HPA051322":"AB_2681441"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.1","Tissue RNA - adrenal gland [nTPM]":"8.1","Tissue RNA - amygdala [nTPM]":"4.8","Tissue RNA - appendix [nTPM]":"11.1","Tissue RNA - basal ganglia [nTPM]":"4.7","Tissue RNA - bone marrow [nTPM]":"6.8","Tissue RNA - breast [nTPM]":"6.7","Tissue RNA - cerebellum [nTPM]":"4.0","Tissue RNA - cerebral cortex [nTPM]":"5.8","Tissue RNA - cervix [nTPM]":"9.3","Tissue RNA - choroid plexus [nTPM]":"7.9","Tissue RNA - colon [nTPM]":"8.7","Tissue RNA - duodenum [nTPM]":"4.4","Tissue RNA - endometrium 1 [nTPM]":"23.6","Tissue RNA - epididymis [nTPM]":"5.7","Tissue RNA - esophagus [nTPM]":"14.9","Tissue RNA - fallopian tube [nTPM]":"11.1","Tissue RNA - gallbladder [nTPM]":"10.6","Tissue RNA - heart muscle [nTPM]":"5.3","Tissue RNA - hippocampal formation [nTPM]":"4.9","Tissue RNA - hypothalamus [nTPM]":"5.3","Tissue RNA - kidney [nTPM]":"12.4","Tissue RNA - liver [nTPM]":"73.4","Tissue RNA - lung [nTPM]":"7.6","Tissue RNA - lymph node [nTPM]":"12.4","Tissue RNA - medulla oblongata [nTPM]":"4.6","Tissue RNA - midbrain [nTPM]":"4.9","Tissue RNA - ovary [nTPM]":"3.4","Tissue RNA - pancreas [nTPM]":"4.7","Tissue RNA - parathyroid gland [nTPM]":"47.6","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"7.8","Tissue RNA - pons [nTPM]":"5.8","Tissue RNA - prostate [nTPM]":"13.5","Tissue RNA - rectum [nTPM]":"12.0","Tissue RNA - retina [nTPM]":"2.4","Tissue RNA - salivary gland [nTPM]":"50.6","Tissue RNA - seminal vesicle [nTPM]":"24.8","Tissue RNA - skeletal muscle [nTPM]":"7.7","Tissue RNA - skin 1 [nTPM]":"4.6","Tissue RNA - small intestine [nTPM]":"8.4","Tissue RNA - smooth muscle [nTPM]":"51.9","Tissue RNA - spinal cord [nTPM]":"4.7","Tissue RNA - spleen [nTPM]":"5.0","Tissue RNA - stomach 1 [nTPM]":"4.1","Tissue RNA - testis [nTPM]":"14.7","Tissue RNA - thalamus [nTPM]":"4.9","Tissue RNA - thymus [nTPM]":"17.3","Tissue RNA - thyroid gland [nTPM]":"4.8","Tissue RNA - tongue [nTPM]":"7.6","Tissue RNA - tonsil [nTPM]":"17.8","Tissue RNA - urinary bladder [nTPM]":"17.7","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"5.0","Cell RNA - A-431 [nTPM]":"77.8","Cell RNA - A549 [nTPM]":"68.5","Cell RNA - AF22 [nTPM]":"95.3","Cell RNA - AN3-CA [nTPM]":"60.5","Cell RNA - ASC diff [nTPM]":"22.9","Cell RNA - ASC TERT1 [nTPM]":"30.9","Cell RNA - BEWO [nTPM]":"138.5","Cell RNA - BJ [nTPM]":"138.8","Cell RNA - BJ hTERT+ [nTPM]":"57.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"141.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"92.0","Cell RNA - CACO-2 [nTPM]":"131.5","Cell RNA - CAPAN-2 [nTPM]":"66.6","Cell RNA - Daudi [nTPM]":"149.8","Cell RNA - EFO-21 [nTPM]":"55.6","Cell RNA - fHDF\/TERT166 [nTPM]":"61.7","Cell RNA - GAMG [nTPM]":"39.4","Cell RNA - HaCaT [nTPM]":"38.6","Cell RNA - HAP1 [nTPM]":"91.5","Cell RNA - HBEC3-KT [nTPM]":"97.0","Cell RNA - HBF TERT88 [nTPM]":"139.5","Cell RNA - HDLM-2 [nTPM]":"66.5","Cell RNA - HEK 293 [nTPM]":"78.0","Cell RNA - HEL [nTPM]":"87.3","Cell RNA - HeLa [nTPM]":"72.3","Cell RNA - Hep G2 [nTPM]":"43.3","Cell RNA - HHSteC [nTPM]":"87.8","Cell RNA - HL-60 [nTPM]":"128.0","Cell RNA - HMC-1 [nTPM]":"56.8","Cell RNA - HSkMC [nTPM]":"34.0","Cell RNA - hTCEpi [nTPM]":"49.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"148.5","Cell RNA - hTERT-HME1 [nTPM]":"103.0","Cell RNA - hTERT-RPE1 [nTPM]":"23.0","Cell RNA - HUVEC TERT2 [nTPM]":"64.1","Cell RNA - JURKAT [nTPM]":"102.2","Cell RNA - K-562 [nTPM]":"84.7","Cell RNA - Karpas-707 [nTPM]":"51.5","Cell RNA - LHCN-M2 [nTPM]":"99.4","Cell RNA - MCF7 [nTPM]":"42.9","Cell RNA - MOLT-4 [nTPM]":"125.0","Cell RNA - NB-4 [nTPM]":"38.1","Cell RNA - NTERA-2 [nTPM]":"126.8","Cell RNA - OE19 [nTPM]":"66.4","Cell RNA - PC-3 [nTPM]":"81.3","Cell RNA - REH [nTPM]":"100.9","Cell RNA - RH-30 [nTPM]":"120.0","Cell RNA - RPMI-8226 [nTPM]":"93.7","Cell RNA - RPTEC TERT1 [nTPM]":"71.4","Cell RNA - RT4 [nTPM]":"69.4","Cell RNA - SCLC-21H [nTPM]":"118.4","Cell RNA - SH-SY5Y [nTPM]":"61.7","Cell RNA - SiHa [nTPM]":"79.2","Cell RNA - SK-BR-3 [nTPM]":"77.7","Cell RNA - SK-MEL-30 [nTPM]":"33.9","Cell RNA - SuSa [nTPM]":"90.8","Cell RNA - T-47d [nTPM]":"30.1","Cell RNA - THP-1 [nTPM]":"152.9","Cell RNA - TIME [nTPM]":"53.5","Cell RNA - U-138 MG [nTPM]":"78.2","Cell RNA - U-2 OS [nTPM]":"119.6","Cell RNA - U-2197 [nTPM]":"61.7","Cell RNA - U-251 MG [nTPM]":"167.2","Cell RNA - U-266\/70 [nTPM]":"36.8","Cell RNA - U-266\/84 [nTPM]":"50.8","Cell RNA - U-698 [nTPM]":"134.5","Cell RNA - U-87 MG [nTPM]":"59.8","Cell RNA - U-937 [nTPM]":"84.5","Cell RNA - WM-115 [nTPM]":"97.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"3.5","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"3.6","Blood RNA - intermediate monocyte [nTPM]":"6.5","Blood RNA - MAIT T-cell [nTPM]":"5.7","Blood RNA - memory B-cell [nTPM]":"5.2","Blood RNA - memory CD4 T-cell [nTPM]":"4.1","Blood RNA - memory CD8 T-cell [nTPM]":"4.3","Blood RNA - myeloid DC [nTPM]":"11.0","Blood RNA - naive B-cell [nTPM]":"4.0","Blood RNA - naive CD4 T-cell [nTPM]":"3.7","Blood RNA - naive CD8 T-cell [nTPM]":"6.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"6.9","Blood RNA - non-classical monocyte [nTPM]":"5.9","Blood RNA - plasmacytoid DC [nTPM]":"11.9","Blood RNA - T-reg [nTPM]":"6.3","Blood RNA - total PBMC [nTPM]":"3.4","Brain RNA - amygdala [nTPM]":"4.8","Brain RNA - basal ganglia [nTPM]":"4.7","Brain RNA - cerebellum [nTPM]":"4.0","Brain RNA - cerebral cortex [nTPM]":"5.8","Brain RNA - hippocampal formation [nTPM]":"4.9","Brain RNA - hypothalamus [nTPM]":"5.3","Brain RNA - medulla oblongata [nTPM]":"4.6","Brain RNA - midbrain [nTPM]":"4.9","Brain RNA - pons [nTPM]":"5.8","Brain RNA - spinal cord [nTPM]":"4.7","Brain RNA - thalamus [nTPM]":"4.9","Brain RNA - white matter [nTPM]":"5.0","Single Cell Type RNA - Adipocytes [nTPM]":"5.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.4","Single Cell Type RNA - Astrocytes [nTPM]":"4.9","Single Cell Type RNA - B-cells [nTPM]":"10.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"12.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"7.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.4","Single Cell Type RNA - dendritic cells [nTPM]":"26.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"19.2","Single Cell Type RNA - Early spermatids [nTPM]":"32.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.8","Single Cell Type RNA - Endothelial cells [nTPM]":"8.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"22.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.4","Single Cell Type RNA - Fibroblasts [nTPM]":"8.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.3","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"15.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"29.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.0","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.4","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"2.8","Single Cell Type RNA - Langerhans cells [nTPM]":"6.2","Single Cell Type RNA - Late spermatids [nTPM]":"27.9","Single Cell Type RNA - Leydig cells [nTPM]":"10.8","Single Cell Type RNA - Macrophages [nTPM]":"6.8","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"8.7","Single Cell Type RNA - Muller glia cells [nTPM]":"5.4","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.3","Single Cell Type RNA - Paneth cells [nTPM]":"1.1","Single Cell Type RNA - Peritubular cells [nTPM]":"24.8","Single Cell Type RNA - Plasma cells [nTPM]":"15.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"25.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.3","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.5","Single Cell Type RNA - Spermatocytes [nTPM]":"11.1","Single Cell Type RNA - Spermatogonia [nTPM]":"40.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.6","Single Cell Type RNA - T-cells [nTPM]":"9.9","Single Cell Type RNA - Theca cells [nTPM]":"20.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.8","Single Cell Type RNA - Urothelial cells [nTPM]":"7.3"},{"Gene":"CTRC","Gene synonym":["CLCR","ELA4"],"Ensembl":"ENSG00000162438","Gene description":"Chymotrypsin C","Uniprot":["Q99895"],"Chromosome":"1","Position":"15438442-15449242","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"3927","RNA tissue specific nTPM":{"pancreas":"25708.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Exocrine glandular cells":"6566.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"168","RNA cancer specific FPKM":{"pancreatic cancer":"236.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046920"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to digestive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 1: Pancreatic cells - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046920":"AB_2679865"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-3"},"Tissue RNA - adipose tissue [nTPM]":"6.5","Tissue RNA - adrenal gland [nTPM]":"1.2","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"2.9","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"2.7","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"1.2","Tissue RNA - duodenum [nTPM]":"1.1","Tissue RNA - endometrium 1 [nTPM]":"1.3","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"1.9","Tissue RNA - fallopian tube [nTPM]":"0.8","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"2.3","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"1.2","Tissue RNA - liver [nTPM]":"3.5","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"5.6","Tissue RNA - pancreas [nTPM]":"25708.5","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.5","Tissue RNA - placenta [nTPM]":"0.7","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"1.8","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"2.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"1.0","Tissue RNA - skin 1 [nTPM]":"2.1","Tissue RNA - small intestine [nTPM]":"1.7","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"2.0","Tissue RNA - stomach 1 [nTPM]":"2.3","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"1.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.6","Tissue RNA - vagina [nTPM]":"1.0","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.8","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"1.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"17.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6566.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.9","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"24.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"673.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"CTSA","Gene synonym":["GSL","PPGB"],"Ensembl":"ENSG00000064601","Gene description":"Cathepsin A","Uniprot":["P10619"],"Chromosome":"20","Position":"45890144-45898824","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Carboxypeptidase","Hydrolase","Protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"368.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"445.6","Proximal enterocytes":"301.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"856.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB024930","HPA031068","HPA072487"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"28000000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 51: Myeloid cells - Hemostasis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB024930":null,"HPA031068":"AB_10601205","HPA072487":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.95e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-2"},"Tissue RNA - adipose tissue [nTPM]":"80.4","Tissue RNA - adrenal gland [nTPM]":"368.3","Tissue RNA - amygdala [nTPM]":"56.8","Tissue RNA - appendix [nTPM]":"75.3","Tissue RNA - basal ganglia [nTPM]":"58.1","Tissue RNA - bone marrow [nTPM]":"75.6","Tissue RNA - breast [nTPM]":"61.9","Tissue RNA - cerebellum [nTPM]":"63.6","Tissue RNA - cerebral cortex [nTPM]":"65.6","Tissue RNA - cervix [nTPM]":"47.6","Tissue RNA - choroid plexus [nTPM]":"96.0","Tissue RNA - colon [nTPM]":"178.6","Tissue RNA - duodenum [nTPM]":"100.9","Tissue RNA - endometrium 1 [nTPM]":"55.1","Tissue RNA - epididymis [nTPM]":"39.0","Tissue RNA - esophagus [nTPM]":"60.4","Tissue RNA - fallopian tube [nTPM]":"39.3","Tissue RNA - gallbladder [nTPM]":"89.7","Tissue RNA - heart muscle [nTPM]":"97.2","Tissue RNA - hippocampal formation [nTPM]":"59.7","Tissue RNA - hypothalamus [nTPM]":"63.8","Tissue RNA - kidney [nTPM]":"188.1","Tissue RNA - liver [nTPM]":"95.7","Tissue RNA - lung [nTPM]":"90.9","Tissue RNA - lymph node [nTPM]":"61.6","Tissue RNA - medulla oblongata [nTPM]":"62.6","Tissue RNA - midbrain [nTPM]":"59.1","Tissue RNA - ovary [nTPM]":"62.2","Tissue RNA - pancreas [nTPM]":"52.9","Tissue RNA - parathyroid gland [nTPM]":"104.4","Tissue RNA - pituitary gland [nTPM]":"43.8","Tissue RNA - placenta [nTPM]":"76.4","Tissue RNA - pons [nTPM]":"61.4","Tissue RNA - prostate [nTPM]":"38.5","Tissue RNA - rectum [nTPM]":"170.4","Tissue RNA - retina [nTPM]":"44.0","Tissue RNA - salivary gland [nTPM]":"61.3","Tissue RNA - seminal vesicle [nTPM]":"48.4","Tissue RNA - skeletal muscle [nTPM]":"56.0","Tissue RNA - skin 1 [nTPM]":"95.2","Tissue RNA - small intestine [nTPM]":"109.2","Tissue RNA - smooth muscle [nTPM]":"67.3","Tissue RNA - spinal cord [nTPM]":"59.4","Tissue RNA - spleen [nTPM]":"108.5","Tissue RNA - stomach 1 [nTPM]":"63.3","Tissue RNA - testis [nTPM]":"33.5","Tissue RNA - thalamus [nTPM]":"70.2","Tissue RNA - thymus [nTPM]":"23.0","Tissue RNA - thyroid gland [nTPM]":"47.4","Tissue RNA - tongue [nTPM]":"61.7","Tissue RNA - tonsil [nTPM]":"58.8","Tissue RNA - urinary bladder [nTPM]":"82.8","Tissue RNA - vagina [nTPM]":"49.2","Tissue RNA - white matter [nTPM]":"68.4","Cell RNA - A-431 [nTPM]":"111.9","Cell RNA - A549 [nTPM]":"114.1","Cell RNA - AF22 [nTPM]":"17.6","Cell RNA - AN3-CA [nTPM]":"89.2","Cell RNA - ASC diff [nTPM]":"856.5","Cell RNA - ASC TERT1 [nTPM]":"438.6","Cell RNA - BEWO [nTPM]":"47.0","Cell RNA - BJ [nTPM]":"150.3","Cell RNA - BJ hTERT+ [nTPM]":"424.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"169.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"217.5","Cell RNA - CACO-2 [nTPM]":"214.4","Cell RNA - CAPAN-2 [nTPM]":"291.8","Cell RNA - Daudi [nTPM]":"24.1","Cell RNA - EFO-21 [nTPM]":"176.2","Cell RNA - fHDF\/TERT166 [nTPM]":"299.9","Cell RNA - GAMG [nTPM]":"638.1","Cell RNA - HaCaT [nTPM]":"168.6","Cell RNA - HAP1 [nTPM]":"55.9","Cell RNA - HBEC3-KT [nTPM]":"105.6","Cell RNA - HBF TERT88 [nTPM]":"95.7","Cell RNA - HDLM-2 [nTPM]":"47.6","Cell RNA - HEK 293 [nTPM]":"53.6","Cell RNA - HEL [nTPM]":"54.3","Cell RNA - HeLa [nTPM]":"53.4","Cell RNA - Hep G2 [nTPM]":"375.9","Cell RNA - HHSteC [nTPM]":"187.3","Cell RNA - HL-60 [nTPM]":"98.0","Cell RNA - HMC-1 [nTPM]":"240.9","Cell RNA - HSkMC [nTPM]":"349.0","Cell RNA - hTCEpi [nTPM]":"123.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"107.9","Cell RNA - hTERT-HME1 [nTPM]":"22.5","Cell RNA - hTERT-RPE1 [nTPM]":"421.9","Cell RNA - HUVEC TERT2 [nTPM]":"190.1","Cell RNA - JURKAT [nTPM]":"28.2","Cell RNA - K-562 [nTPM]":"61.0","Cell RNA - Karpas-707 [nTPM]":"355.1","Cell RNA - LHCN-M2 [nTPM]":"186.9","Cell RNA - MCF7 [nTPM]":"232.1","Cell RNA - MOLT-4 [nTPM]":"25.8","Cell RNA - NB-4 [nTPM]":"82.4","Cell RNA - NTERA-2 [nTPM]":"19.4","Cell RNA - OE19 [nTPM]":"172.6","Cell RNA - PC-3 [nTPM]":"272.1","Cell RNA - REH [nTPM]":"37.8","Cell RNA - RH-30 [nTPM]":"107.3","Cell RNA - RPMI-8226 [nTPM]":"135.7","Cell RNA - RPTEC TERT1 [nTPM]":"138.2","Cell RNA - RT4 [nTPM]":"96.7","Cell RNA - SCLC-21H [nTPM]":"36.9","Cell RNA - SH-SY5Y [nTPM]":"37.8","Cell RNA - SiHa [nTPM]":"263.2","Cell RNA - SK-BR-3 [nTPM]":"450.3","Cell RNA - SK-MEL-30 [nTPM]":"444.4","Cell RNA - SuSa [nTPM]":"51.5","Cell RNA - T-47d [nTPM]":"108.5","Cell RNA - THP-1 [nTPM]":"141.8","Cell RNA - TIME [nTPM]":"172.5","Cell RNA - U-138 MG [nTPM]":"335.0","Cell RNA - U-2 OS [nTPM]":"76.2","Cell RNA - U-2197 [nTPM]":"178.9","Cell RNA - U-251 MG [nTPM]":"123.7","Cell RNA - U-266\/70 [nTPM]":"162.1","Cell RNA - U-266\/84 [nTPM]":"238.5","Cell RNA - U-698 [nTPM]":"15.7","Cell RNA - U-87 MG [nTPM]":"599.3","Cell RNA - U-937 [nTPM]":"128.6","Cell RNA - WM-115 [nTPM]":"142.4","Blood RNA - basophil [nTPM]":"480.7","Blood RNA - classical monocyte [nTPM]":"305.9","Blood RNA - eosinophil [nTPM]":"530.5","Blood RNA - gdT-cell [nTPM]":"44.9","Blood RNA - intermediate monocyte [nTPM]":"168.8","Blood RNA - MAIT T-cell [nTPM]":"185.5","Blood RNA - memory B-cell [nTPM]":"42.0","Blood RNA - memory CD4 T-cell [nTPM]":"75.6","Blood RNA - memory CD8 T-cell [nTPM]":"78.3","Blood RNA - myeloid DC [nTPM]":"102.4","Blood RNA - naive B-cell [nTPM]":"25.7","Blood RNA - naive CD4 T-cell [nTPM]":"26.6","Blood RNA - naive CD8 T-cell [nTPM]":"39.8","Blood RNA - neutrophil [nTPM]":"152.4","Blood RNA - NK-cell [nTPM]":"81.2","Blood RNA - non-classical monocyte [nTPM]":"120.1","Blood RNA - plasmacytoid DC [nTPM]":"40.6","Blood RNA - T-reg [nTPM]":"155.4","Blood RNA - total PBMC [nTPM]":"378.1","Brain RNA - amygdala [nTPM]":"56.8","Brain RNA - basal ganglia [nTPM]":"58.1","Brain RNA - cerebellum [nTPM]":"63.6","Brain RNA - cerebral cortex [nTPM]":"65.6","Brain RNA - hippocampal formation [nTPM]":"59.7","Brain RNA - hypothalamus [nTPM]":"63.8","Brain RNA - medulla oblongata [nTPM]":"62.6","Brain RNA - midbrain [nTPM]":"59.1","Brain RNA - pons [nTPM]":"61.4","Brain RNA - spinal cord [nTPM]":"59.4","Brain RNA - thalamus [nTPM]":"70.2","Brain RNA - white matter [nTPM]":"68.4","Single Cell Type RNA - Adipocytes [nTPM]":"53.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"32.6","Single Cell Type RNA - Astrocytes [nTPM]":"26.1","Single Cell Type RNA - B-cells [nTPM]":"38.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"24.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"38.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"88.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.6","Single Cell Type RNA - Bipolar cells [nTPM]":"58.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"65.8","Single Cell Type RNA - Club cells [nTPM]":"64.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"71.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"60.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"104.1","Single Cell Type RNA - dendritic cells [nTPM]":"27.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"445.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"39.2","Single Cell Type RNA - Ductal cells [nTPM]":"246.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"39.5","Single Cell Type RNA - Endothelial cells [nTPM]":"56.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"54.0","Single Cell Type RNA - Erythroid cells [nTPM]":"22.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"20.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"166.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"109.2","Single Cell Type RNA - Fibroblasts [nTPM]":"86.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"29.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"62.4","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"50.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"102.1","Single Cell Type RNA - Hepatocytes [nTPM]":"67.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"297.1","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"74.5","Single Cell Type RNA - Ionocytes [nTPM]":"95.6","Single Cell Type RNA - Kupffer cells [nTPM]":"177.1","Single Cell Type RNA - Langerhans cells [nTPM]":"25.1","Single Cell Type RNA - Late spermatids [nTPM]":"4.8","Single Cell Type RNA - Leydig cells [nTPM]":"32.9","Single Cell Type RNA - Macrophages [nTPM]":"273.1","Single Cell Type RNA - Melanocytes [nTPM]":"112.1","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"135.6","Single Cell Type RNA - Muller glia cells [nTPM]":"86.6","Single Cell Type RNA - NK-cells [nTPM]":"37.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"135.0","Single Cell Type RNA - Paneth cells [nTPM]":"216.0","Single Cell Type RNA - Peritubular cells [nTPM]":"27.4","Single Cell Type RNA - Plasma cells [nTPM]":"41.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"301.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"245.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"34.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"46.1","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"33.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"54.5","Single Cell Type RNA - Spermatocytes [nTPM]":"15.3","Single Cell Type RNA - Spermatogonia [nTPM]":"31.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"24.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"144.1","Single Cell Type RNA - T-cells [nTPM]":"49.1","Single Cell Type RNA - Theca cells [nTPM]":"91.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"113.9","Single Cell Type RNA - Urothelial cells [nTPM]":"36.2"},{"Gene":"CTSB","Gene synonym":[],"Ensembl":"ENSG00000164733","Gene description":"Cathepsin B","Uniprot":["P07858"],"Chromosome":"8","Position":"11842524-11869533","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"2744.5","Kupffer cells":"1774.9","Macrophages":"1224.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"thyroid cancer":"1446.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"390.6","classical monocyte":"610.1","intermediate monocyte":"467.3","myeloid DC":"287.4","non-classical monocyte":"307.6","plasmacytoid DC":"410.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"410.1","granulocytes":"390.6","monocytes":"610.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+":"1607.5","fHDF\/TERT166":"1436.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000457","HPA018156","HPA048998"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"100000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"CAB000457":null,"HPA018156":"AB_1846069","HPA048998":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.76e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.02e-4"},"Tissue RNA - adipose tissue [nTPM]":"443.9","Tissue RNA - adrenal gland [nTPM]":"304.5","Tissue RNA - amygdala [nTPM]":"65.6","Tissue RNA - appendix [nTPM]":"399.7","Tissue RNA - basal ganglia [nTPM]":"71.2","Tissue RNA - bone marrow [nTPM]":"87.0","Tissue RNA - breast [nTPM]":"249.0","Tissue RNA - cerebellum [nTPM]":"65.9","Tissue RNA - cerebral cortex [nTPM]":"77.2","Tissue RNA - cervix [nTPM]":"583.2","Tissue RNA - choroid plexus [nTPM]":"101.0","Tissue RNA - colon [nTPM]":"312.4","Tissue RNA - duodenum [nTPM]":"120.8","Tissue RNA - endometrium 1 [nTPM]":"379.2","Tissue RNA - epididymis [nTPM]":"116.9","Tissue RNA - esophagus [nTPM]":"421.6","Tissue RNA - fallopian tube [nTPM]":"368.4","Tissue RNA - gallbladder [nTPM]":"230.6","Tissue RNA - heart muscle [nTPM]":"447.0","Tissue RNA - hippocampal formation [nTPM]":"64.7","Tissue RNA - hypothalamus [nTPM]":"95.5","Tissue RNA - kidney [nTPM]":"420.6","Tissue RNA - liver [nTPM]":"497.2","Tissue RNA - lung [nTPM]":"428.9","Tissue RNA - lymph node [nTPM]":"289.6","Tissue RNA - medulla oblongata [nTPM]":"100.4","Tissue RNA - midbrain [nTPM]":"90.8","Tissue RNA - ovary [nTPM]":"169.1","Tissue RNA - pancreas [nTPM]":"135.4","Tissue RNA - parathyroid gland [nTPM]":"79.6","Tissue RNA - pituitary gland [nTPM]":"156.8","Tissue RNA - placenta [nTPM]":"253.2","Tissue RNA - pons [nTPM]":"107.4","Tissue RNA - prostate [nTPM]":"255.5","Tissue RNA - rectum [nTPM]":"159.3","Tissue RNA - retina [nTPM]":"33.6","Tissue RNA - salivary gland [nTPM]":"437.3","Tissue RNA - seminal vesicle [nTPM]":"156.6","Tissue RNA - skeletal muscle [nTPM]":"237.4","Tissue RNA - skin 1 [nTPM]":"184.7","Tissue RNA - small intestine [nTPM]":"260.2","Tissue RNA - smooth muscle [nTPM]":"316.1","Tissue RNA - spinal cord [nTPM]":"91.9","Tissue RNA - spleen [nTPM]":"521.1","Tissue RNA - stomach 1 [nTPM]":"194.3","Tissue RNA - testis [nTPM]":"33.2","Tissue RNA - thalamus [nTPM]":"204.5","Tissue RNA - thymus [nTPM]":"60.9","Tissue RNA - thyroid gland [nTPM]":"1150.7","Tissue RNA - tongue [nTPM]":"99.3","Tissue RNA - tonsil [nTPM]":"104.0","Tissue RNA - urinary bladder [nTPM]":"431.9","Tissue RNA - vagina [nTPM]":"477.8","Tissue RNA - white matter [nTPM]":"159.2","Cell RNA - A-431 [nTPM]":"66.6","Cell RNA - A549 [nTPM]":"283.4","Cell RNA - AF22 [nTPM]":"4.0","Cell RNA - AN3-CA [nTPM]":"94.9","Cell RNA - ASC diff [nTPM]":"657.3","Cell RNA - ASC TERT1 [nTPM]":"754.5","Cell RNA - BEWO [nTPM]":"128.3","Cell RNA - BJ [nTPM]":"885.0","Cell RNA - BJ hTERT+ [nTPM]":"1607.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"258.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"299.5","Cell RNA - CACO-2 [nTPM]":"10.3","Cell RNA - CAPAN-2 [nTPM]":"294.4","Cell RNA - Daudi [nTPM]":"1.5","Cell RNA - EFO-21 [nTPM]":"32.2","Cell RNA - fHDF\/TERT166 [nTPM]":"1436.1","Cell RNA - GAMG [nTPM]":"419.3","Cell RNA - HaCaT [nTPM]":"279.5","Cell RNA - HAP1 [nTPM]":"65.3","Cell RNA - HBEC3-KT [nTPM]":"157.1","Cell RNA - HBF TERT88 [nTPM]":"195.6","Cell RNA - HDLM-2 [nTPM]":"25.9","Cell RNA - HEK 293 [nTPM]":"52.6","Cell RNA - HEL [nTPM]":"58.8","Cell RNA - HeLa [nTPM]":"10.0","Cell RNA - Hep G2 [nTPM]":"397.1","Cell RNA - HHSteC [nTPM]":"479.2","Cell RNA - HL-60 [nTPM]":"7.7","Cell RNA - HMC-1 [nTPM]":"73.7","Cell RNA - HSkMC [nTPM]":"296.4","Cell RNA - hTCEpi [nTPM]":"532.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"327.2","Cell RNA - hTERT-HME1 [nTPM]":"427.3","Cell RNA - hTERT-RPE1 [nTPM]":"611.5","Cell RNA - HUVEC TERT2 [nTPM]":"33.4","Cell RNA - JURKAT [nTPM]":"20.2","Cell RNA - K-562 [nTPM]":"81.7","Cell RNA - Karpas-707 [nTPM]":"260.7","Cell RNA - LHCN-M2 [nTPM]":"194.6","Cell RNA - MCF7 [nTPM]":"62.5","Cell RNA - MOLT-4 [nTPM]":"6.5","Cell RNA - NB-4 [nTPM]":"23.1","Cell RNA - NTERA-2 [nTPM]":"16.3","Cell RNA - OE19 [nTPM]":"839.7","Cell RNA - PC-3 [nTPM]":"91.3","Cell RNA - REH [nTPM]":"33.6","Cell RNA - RH-30 [nTPM]":"39.3","Cell RNA - RPMI-8226 [nTPM]":"202.7","Cell RNA - RPTEC TERT1 [nTPM]":"2.6","Cell RNA - RT4 [nTPM]":"121.1","Cell RNA - SCLC-21H [nTPM]":"4.9","Cell RNA - SH-SY5Y [nTPM]":"68.6","Cell RNA - SiHa [nTPM]":"165.1","Cell RNA - SK-BR-3 [nTPM]":"68.6","Cell RNA - SK-MEL-30 [nTPM]":"514.6","Cell RNA - SuSa [nTPM]":"110.1","Cell RNA - T-47d [nTPM]":"97.8","Cell RNA - THP-1 [nTPM]":"68.7","Cell RNA - TIME [nTPM]":"922.4","Cell RNA - U-138 MG [nTPM]":"766.5","Cell RNA - U-2 OS [nTPM]":"111.9","Cell RNA - U-2197 [nTPM]":"129.9","Cell RNA - U-251 MG [nTPM]":"259.3","Cell RNA - U-266\/70 [nTPM]":"182.7","Cell RNA - U-266\/84 [nTPM]":"178.5","Cell RNA - U-698 [nTPM]":"4.8","Cell RNA - U-87 MG [nTPM]":"432.5","Cell RNA - U-937 [nTPM]":"22.9","Cell RNA - WM-115 [nTPM]":"249.4","Blood RNA - basophil [nTPM]":"390.6","Blood RNA - classical monocyte [nTPM]":"610.1","Blood RNA - eosinophil [nTPM]":"90.6","Blood RNA - gdT-cell [nTPM]":"26.3","Blood RNA - intermediate monocyte [nTPM]":"467.3","Blood RNA - MAIT T-cell [nTPM]":"35.4","Blood RNA - memory B-cell [nTPM]":"44.1","Blood RNA - memory CD4 T-cell [nTPM]":"79.0","Blood RNA - memory CD8 T-cell [nTPM]":"31.5","Blood RNA - myeloid DC [nTPM]":"287.4","Blood RNA - naive B-cell [nTPM]":"38.8","Blood RNA - naive CD4 T-cell [nTPM]":"48.3","Blood RNA - naive CD8 T-cell [nTPM]":"21.5","Blood RNA - neutrophil [nTPM]":"97.8","Blood RNA - NK-cell [nTPM]":"31.3","Blood RNA - non-classical monocyte [nTPM]":"307.6","Blood RNA - plasmacytoid DC [nTPM]":"410.1","Blood RNA - T-reg [nTPM]":"78.7","Blood RNA - total PBMC [nTPM]":"703.7","Brain RNA - amygdala [nTPM]":"65.6","Brain RNA - basal ganglia [nTPM]":"71.2","Brain RNA - cerebellum [nTPM]":"65.9","Brain RNA - cerebral cortex [nTPM]":"77.2","Brain RNA - hippocampal formation [nTPM]":"64.7","Brain RNA - hypothalamus [nTPM]":"95.5","Brain RNA - medulla oblongata [nTPM]":"100.4","Brain RNA - midbrain [nTPM]":"90.8","Brain RNA - pons [nTPM]":"107.4","Brain RNA - spinal cord [nTPM]":"91.9","Brain RNA - thalamus [nTPM]":"204.5","Brain RNA - white matter [nTPM]":"159.2","Single Cell Type RNA - Adipocytes [nTPM]":"87.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"109.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"171.4","Single Cell Type RNA - Astrocytes [nTPM]":"17.6","Single Cell Type RNA - B-cells [nTPM]":"54.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"54.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"441.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"563.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"54.7","Single Cell Type RNA - Bipolar cells [nTPM]":"55.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"94.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"74.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"320.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"165.8","Single Cell Type RNA - Club cells [nTPM]":"331.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"114.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"279.4","Single Cell Type RNA - dendritic cells [nTPM]":"122.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"147.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"27.4","Single Cell Type RNA - Ductal cells [nTPM]":"294.6","Single Cell Type RNA - Early spermatids [nTPM]":"15.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"105.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"240.1","Single Cell Type RNA - Endothelial cells [nTPM]":"163.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"154.7","Single Cell Type RNA - Erythroid cells [nTPM]":"210.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"36.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"238.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"341.7","Single Cell Type RNA - Fibroblasts [nTPM]":"155.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"44.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"183.5","Single Cell Type RNA - granulocytes [nTPM]":"179.4","Single Cell Type RNA - Granulosa cells [nTPM]":"105.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"204.2","Single Cell Type RNA - Hepatocytes [nTPM]":"239.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"2744.5","Single Cell Type RNA - Horizontal cells [nTPM]":"58.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"42.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"94.2","Single Cell Type RNA - Ionocytes [nTPM]":"158.7","Single Cell Type RNA - Kupffer cells [nTPM]":"1774.9","Single Cell Type RNA - Langerhans cells [nTPM]":"436.5","Single Cell Type RNA - Late spermatids [nTPM]":"18.5","Single Cell Type RNA - Leydig cells [nTPM]":"76.4","Single Cell Type RNA - Macrophages [nTPM]":"1224.3","Single Cell Type RNA - Melanocytes [nTPM]":"161.9","Single Cell Type RNA - Microglial cells [nTPM]":"70.3","Single Cell Type RNA - monocytes [nTPM]":"373.1","Single Cell Type RNA - Muller glia cells [nTPM]":"117.4","Single Cell Type RNA - NK-cells [nTPM]":"24.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"363.9","Single Cell Type RNA - Paneth cells [nTPM]":"154.0","Single Cell Type RNA - Peritubular cells [nTPM]":"92.9","Single Cell Type RNA - Plasma cells [nTPM]":"47.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"295.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"198.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"351.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"180.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"40.0","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"39.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"149.9","Single Cell Type RNA - Spermatocytes [nTPM]":"10.8","Single Cell Type RNA - Spermatogonia [nTPM]":"21.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"160.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"40.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"649.6","Single Cell Type RNA - T-cells [nTPM]":"56.0","Single Cell Type RNA - Theca cells [nTPM]":"32.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"139.6","Single Cell Type RNA - Urothelial cells [nTPM]":"321.4"},{"Gene":"CTSC","Gene synonym":["DPP1","PALS","PLS"],"Ensembl":"ENSG00000109861","Gene description":"Cathepsin C","Uniprot":["P53634"],"Chromosome":"11","Position":"88265069-88359684","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Disease variant","Palmoplantar keratoderma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"900.7","Club cells":"471.8","Hofbauer cells":"1100.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+":"1078.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025364","HPA066610","HPA068434"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"19000000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 19: Lung - Lung function","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB025364":null,"HPA066610":"AB_2685694","HPA068434":"AB_2685989"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.30e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.80e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Tissue RNA - adipose tissue [nTPM]":"173.2","Tissue RNA - adrenal gland [nTPM]":"60.7","Tissue RNA - amygdala [nTPM]":"9.9","Tissue RNA - appendix [nTPM]":"185.1","Tissue RNA - basal ganglia [nTPM]":"9.6","Tissue RNA - bone marrow [nTPM]":"71.7","Tissue RNA - breast [nTPM]":"63.4","Tissue RNA - cerebellum [nTPM]":"11.1","Tissue RNA - cerebral cortex [nTPM]":"24.9","Tissue RNA - cervix [nTPM]":"77.9","Tissue RNA - choroid plexus [nTPM]":"14.2","Tissue RNA - colon [nTPM]":"143.1","Tissue RNA - duodenum [nTPM]":"121.0","Tissue RNA - endometrium 1 [nTPM]":"43.9","Tissue RNA - epididymis [nTPM]":"28.5","Tissue RNA - esophagus [nTPM]":"63.3","Tissue RNA - fallopian tube [nTPM]":"54.0","Tissue RNA - gallbladder [nTPM]":"182.0","Tissue RNA - heart muscle [nTPM]":"38.5","Tissue RNA - hippocampal formation [nTPM]":"9.5","Tissue RNA - hypothalamus [nTPM]":"10.1","Tissue RNA - kidney [nTPM]":"234.7","Tissue RNA - liver [nTPM]":"82.0","Tissue RNA - lung [nTPM]":"272.6","Tissue RNA - lymph node [nTPM]":"243.7","Tissue RNA - medulla oblongata [nTPM]":"14.0","Tissue RNA - midbrain [nTPM]":"11.9","Tissue RNA - ovary [nTPM]":"22.1","Tissue RNA - pancreas [nTPM]":"52.2","Tissue RNA - parathyroid gland [nTPM]":"42.4","Tissue RNA - pituitary gland [nTPM]":"39.3","Tissue RNA - placenta [nTPM]":"253.3","Tissue RNA - pons [nTPM]":"13.3","Tissue RNA - prostate [nTPM]":"26.0","Tissue RNA - rectum [nTPM]":"191.5","Tissue RNA - retina [nTPM]":"3.7","Tissue RNA - salivary gland [nTPM]":"131.6","Tissue RNA - seminal vesicle [nTPM]":"28.9","Tissue RNA - skeletal muscle [nTPM]":"18.8","Tissue RNA - skin 1 [nTPM]":"29.6","Tissue RNA - small intestine [nTPM]":"128.8","Tissue RNA - smooth muscle [nTPM]":"88.9","Tissue RNA - spinal cord [nTPM]":"11.5","Tissue RNA - spleen [nTPM]":"197.2","Tissue RNA - stomach 1 [nTPM]":"73.6","Tissue RNA - testis [nTPM]":"22.8","Tissue RNA - thalamus [nTPM]":"19.5","Tissue RNA - thymus [nTPM]":"63.7","Tissue RNA - thyroid gland [nTPM]":"43.6","Tissue RNA - tongue [nTPM]":"31.9","Tissue RNA - tonsil [nTPM]":"140.6","Tissue RNA - urinary bladder [nTPM]":"176.3","Tissue RNA - vagina [nTPM]":"43.3","Tissue RNA - white matter [nTPM]":"21.3","Cell RNA - A-431 [nTPM]":"80.3","Cell RNA - A549 [nTPM]":"75.9","Cell RNA - AF22 [nTPM]":"27.6","Cell RNA - AN3-CA [nTPM]":"69.9","Cell RNA - ASC diff [nTPM]":"103.7","Cell RNA - ASC TERT1 [nTPM]":"286.1","Cell RNA - BEWO [nTPM]":"218.4","Cell RNA - BJ [nTPM]":"626.5","Cell RNA - BJ hTERT+ [nTPM]":"1078.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"372.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"270.3","Cell RNA - CACO-2 [nTPM]":"194.7","Cell RNA - CAPAN-2 [nTPM]":"361.3","Cell RNA - Daudi [nTPM]":"117.3","Cell RNA - EFO-21 [nTPM]":"278.9","Cell RNA - fHDF\/TERT166 [nTPM]":"365.2","Cell RNA - GAMG [nTPM]":"84.3","Cell RNA - HaCaT [nTPM]":"133.6","Cell RNA - HAP1 [nTPM]":"50.4","Cell RNA - HBEC3-KT [nTPM]":"269.2","Cell RNA - HBF TERT88 [nTPM]":"341.9","Cell RNA - HDLM-2 [nTPM]":"204.7","Cell RNA - HEK 293 [nTPM]":"82.8","Cell RNA - HEL [nTPM]":"144.5","Cell RNA - HeLa [nTPM]":"188.0","Cell RNA - Hep G2 [nTPM]":"233.5","Cell RNA - HHSteC [nTPM]":"140.2","Cell RNA - HL-60 [nTPM]":"188.9","Cell RNA - HMC-1 [nTPM]":"108.7","Cell RNA - HSkMC [nTPM]":"419.1","Cell RNA - hTCEpi [nTPM]":"198.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"284.5","Cell RNA - hTERT-HME1 [nTPM]":"697.4","Cell RNA - hTERT-RPE1 [nTPM]":"302.1","Cell RNA - HUVEC TERT2 [nTPM]":"377.6","Cell RNA - JURKAT [nTPM]":"122.3","Cell RNA - K-562 [nTPM]":"155.3","Cell RNA - Karpas-707 [nTPM]":"145.4","Cell RNA - LHCN-M2 [nTPM]":"54.8","Cell RNA - MCF7 [nTPM]":"14.8","Cell RNA - MOLT-4 [nTPM]":"89.1","Cell RNA - NB-4 [nTPM]":"295.1","Cell RNA - NTERA-2 [nTPM]":"172.2","Cell RNA - OE19 [nTPM]":"551.5","Cell RNA - PC-3 [nTPM]":"244.9","Cell RNA - REH [nTPM]":"113.6","Cell RNA - RH-30 [nTPM]":"30.7","Cell RNA - RPMI-8226 [nTPM]":"227.0","Cell RNA - RPTEC TERT1 [nTPM]":"451.3","Cell RNA - RT4 [nTPM]":"106.6","Cell RNA - SCLC-21H [nTPM]":"8.8","Cell RNA - SH-SY5Y [nTPM]":"66.8","Cell RNA - SiHa [nTPM]":"81.2","Cell RNA - SK-BR-3 [nTPM]":"114.9","Cell RNA - SK-MEL-30 [nTPM]":"80.6","Cell RNA - SuSa [nTPM]":"185.4","Cell RNA - T-47d [nTPM]":"27.9","Cell RNA - THP-1 [nTPM]":"152.7","Cell RNA - TIME [nTPM]":"149.3","Cell RNA - U-138 MG [nTPM]":"23.5","Cell RNA - U-2 OS [nTPM]":"190.5","Cell RNA - U-2197 [nTPM]":"156.8","Cell RNA - U-251 MG [nTPM]":"364.6","Cell RNA - U-266\/70 [nTPM]":"61.9","Cell RNA - U-266\/84 [nTPM]":"81.0","Cell RNA - U-698 [nTPM]":"122.9","Cell RNA - U-87 MG [nTPM]":"56.8","Cell RNA - U-937 [nTPM]":"435.8","Cell RNA - WM-115 [nTPM]":"122.4","Blood RNA - basophil [nTPM]":"85.5","Blood RNA - classical monocyte [nTPM]":"203.8","Blood RNA - eosinophil [nTPM]":"309.7","Blood RNA - gdT-cell [nTPM]":"230.1","Blood RNA - intermediate monocyte [nTPM]":"415.6","Blood RNA - MAIT T-cell [nTPM]":"194.9","Blood RNA - memory B-cell [nTPM]":"47.2","Blood RNA - memory CD4 T-cell [nTPM]":"99.6","Blood RNA - memory CD8 T-cell [nTPM]":"198.2","Blood RNA - myeloid DC [nTPM]":"209.9","Blood RNA - naive B-cell [nTPM]":"26.3","Blood RNA - naive CD4 T-cell [nTPM]":"49.5","Blood RNA - naive CD8 T-cell [nTPM]":"115.3","Blood RNA - neutrophil [nTPM]":"215.0","Blood RNA - NK-cell [nTPM]":"200.5","Blood RNA - non-classical monocyte [nTPM]":"582.9","Blood RNA - plasmacytoid DC [nTPM]":"425.0","Blood RNA - T-reg [nTPM]":"162.7","Blood RNA - total PBMC [nTPM]":"243.3","Brain RNA - amygdala [nTPM]":"9.9","Brain RNA - basal ganglia [nTPM]":"9.6","Brain RNA - cerebellum [nTPM]":"11.1","Brain RNA - cerebral cortex [nTPM]":"24.9","Brain RNA - hippocampal formation [nTPM]":"9.5","Brain RNA - hypothalamus [nTPM]":"10.1","Brain RNA - medulla oblongata [nTPM]":"14.0","Brain RNA - midbrain [nTPM]":"11.9","Brain RNA - pons [nTPM]":"13.3","Brain RNA - spinal cord [nTPM]":"11.5","Brain RNA - thalamus [nTPM]":"19.5","Brain RNA - white matter [nTPM]":"21.3","Single Cell Type RNA - Adipocytes [nTPM]":"78.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"88.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"40.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"900.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"33.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"52.9","Single Cell Type RNA - Club cells [nTPM]":"471.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"414.1","Single Cell Type RNA - dendritic cells [nTPM]":"330.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"37.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"29.4","Single Cell Type RNA - Ductal cells [nTPM]":"29.8","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"135.6","Single Cell Type RNA - Endothelial cells [nTPM]":"94.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.4","Single Cell Type RNA - Erythroid cells [nTPM]":"29.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"90.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"159.2","Single Cell Type RNA - Fibroblasts [nTPM]":"114.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"39.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.2","Single Cell Type RNA - granulocytes [nTPM]":"75.3","Single Cell Type RNA - Granulosa cells [nTPM]":"25.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.4","Single Cell Type RNA - Hepatocytes [nTPM]":"15.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"1100.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.4","Single Cell Type RNA - Ionocytes [nTPM]":"158.7","Single Cell Type RNA - Kupffer cells [nTPM]":"344.7","Single Cell Type RNA - Langerhans cells [nTPM]":"200.7","Single Cell Type RNA - Late spermatids [nTPM]":"7.9","Single Cell Type RNA - Leydig cells [nTPM]":"198.5","Single Cell Type RNA - Macrophages [nTPM]":"391.7","Single Cell Type RNA - Melanocytes [nTPM]":"48.0","Single Cell Type RNA - Microglial cells [nTPM]":"61.8","Single Cell Type RNA - monocytes [nTPM]":"185.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"299.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"44.8","Single Cell Type RNA - Paneth cells [nTPM]":"72.3","Single Cell Type RNA - Peritubular cells [nTPM]":"25.6","Single Cell Type RNA - Plasma cells [nTPM]":"78.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"166.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"93.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"150.8","Single Cell Type RNA - Spermatocytes [nTPM]":"3.0","Single Cell Type RNA - Spermatogonia [nTPM]":"11.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"43.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"227.3","Single Cell Type RNA - T-cells [nTPM]":"170.6","Single Cell Type RNA - Theca cells [nTPM]":"286.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"44.9","Single Cell Type RNA - Urothelial cells [nTPM]":"16.1"},{"Gene":"CTSD","Gene synonym":["CLN10","CPSD"],"Ensembl":"ENSG00000117984","Gene description":"Cathepsin D","Uniprot":["P07339"],"Chromosome":"11","Position":"1752752-1764573","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Aspartyl protease","Hydrolase","Protease"],"Disease involvement":["Alzheimer disease","Cancer-related genes","Disease variant","Neurodegeneration","Neuronal ceroid lipofuscinosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"1475.9","Hofbauer cells":"3763.5","Macrophages":"1512.6","Proximal enterocytes":"1699.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"2596.6","hTERT-RPE1":"2780.1","SK-BR-3":"2488.5"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000109","HPA003001"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"370000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB000109":null,"HPA003001":"AB_1078404"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.46e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.93e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Tissue RNA - adipose tissue [nTPM]":"318.6","Tissue RNA - adrenal gland [nTPM]":"734.6","Tissue RNA - amygdala [nTPM]":"147.0","Tissue RNA - appendix [nTPM]":"204.9","Tissue RNA - basal ganglia [nTPM]":"181.9","Tissue RNA - bone marrow [nTPM]":"499.0","Tissue RNA - breast [nTPM]":"244.0","Tissue RNA - cerebellum [nTPM]":"186.0","Tissue RNA - cerebral cortex [nTPM]":"156.5","Tissue RNA - cervix [nTPM]":"270.8","Tissue RNA - choroid plexus [nTPM]":"672.7","Tissue RNA - colon [nTPM]":"298.0","Tissue RNA - duodenum [nTPM]":"387.6","Tissue RNA - endometrium 1 [nTPM]":"170.7","Tissue RNA - epididymis [nTPM]":"82.8","Tissue RNA - esophagus [nTPM]":"319.4","Tissue RNA - fallopian tube [nTPM]":"171.6","Tissue RNA - gallbladder [nTPM]":"438.4","Tissue RNA - heart muscle [nTPM]":"444.1","Tissue RNA - hippocampal formation [nTPM]":"187.8","Tissue RNA - hypothalamus [nTPM]":"223.6","Tissue RNA - kidney [nTPM]":"691.6","Tissue RNA - liver [nTPM]":"464.8","Tissue RNA - lung [nTPM]":"539.6","Tissue RNA - lymph node [nTPM]":"241.0","Tissue RNA - medulla oblongata [nTPM]":"247.6","Tissue RNA - midbrain [nTPM]":"206.6","Tissue RNA - ovary [nTPM]":"130.7","Tissue RNA - pancreas [nTPM]":"284.8","Tissue RNA - parathyroid gland [nTPM]":"137.3","Tissue RNA - pituitary gland [nTPM]":"131.5","Tissue RNA - placenta [nTPM]":"180.7","Tissue RNA - pons [nTPM]":"228.6","Tissue RNA - prostate [nTPM]":"138.2","Tissue RNA - rectum [nTPM]":"153.4","Tissue RNA - retina [nTPM]":"48.3","Tissue RNA - salivary gland [nTPM]":"422.1","Tissue RNA - seminal vesicle [nTPM]":"231.7","Tissue RNA - skeletal muscle [nTPM]":"590.3","Tissue RNA - skin 1 [nTPM]":"340.9","Tissue RNA - small intestine [nTPM]":"398.3","Tissue RNA - smooth muscle [nTPM]":"105.0","Tissue RNA - spinal cord [nTPM]":"188.9","Tissue RNA - spleen [nTPM]":"442.0","Tissue RNA - stomach 1 [nTPM]":"287.2","Tissue RNA - testis [nTPM]":"88.9","Tissue RNA - thalamus [nTPM]":"334.4","Tissue RNA - thymus [nTPM]":"78.1","Tissue RNA - thyroid gland [nTPM]":"182.1","Tissue RNA - tongue [nTPM]":"178.2","Tissue RNA - tonsil [nTPM]":"123.1","Tissue RNA - urinary bladder [nTPM]":"296.4","Tissue RNA - vagina [nTPM]":"307.5","Tissue RNA - white matter [nTPM]":"367.1","Cell RNA - A-431 [nTPM]":"204.6","Cell RNA - A549 [nTPM]":"578.9","Cell RNA - AF22 [nTPM]":"51.4","Cell RNA - AN3-CA [nTPM]":"246.2","Cell RNA - ASC diff [nTPM]":"586.5","Cell RNA - ASC TERT1 [nTPM]":"206.3","Cell RNA - BEWO [nTPM]":"112.1","Cell RNA - BJ [nTPM]":"149.4","Cell RNA - BJ hTERT+ [nTPM]":"362.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"161.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"182.8","Cell RNA - CACO-2 [nTPM]":"147.5","Cell RNA - CAPAN-2 [nTPM]":"2596.6","Cell RNA - Daudi [nTPM]":"49.2","Cell RNA - EFO-21 [nTPM]":"376.8","Cell RNA - fHDF\/TERT166 [nTPM]":"285.8","Cell RNA - GAMG [nTPM]":"1265.6","Cell RNA - HaCaT [nTPM]":"1072.2","Cell RNA - HAP1 [nTPM]":"63.7","Cell RNA - HBEC3-KT [nTPM]":"142.6","Cell RNA - HBF TERT88 [nTPM]":"35.8","Cell RNA - HDLM-2 [nTPM]":"206.7","Cell RNA - HEK 293 [nTPM]":"222.9","Cell RNA - HEL [nTPM]":"70.4","Cell RNA - HeLa [nTPM]":"92.5","Cell RNA - Hep G2 [nTPM]":"196.5","Cell RNA - HHSteC [nTPM]":"736.2","Cell RNA - HL-60 [nTPM]":"171.4","Cell RNA - HMC-1 [nTPM]":"787.7","Cell RNA - HSkMC [nTPM]":"350.9","Cell RNA - hTCEpi [nTPM]":"621.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"82.5","Cell RNA - hTERT-HME1 [nTPM]":"136.9","Cell RNA - hTERT-RPE1 [nTPM]":"2780.1","Cell RNA - HUVEC TERT2 [nTPM]":"128.2","Cell RNA - JURKAT [nTPM]":"62.1","Cell RNA - K-562 [nTPM]":"89.2","Cell RNA - Karpas-707 [nTPM]":"267.6","Cell RNA - LHCN-M2 [nTPM]":"263.3","Cell RNA - MCF7 [nTPM]":"832.6","Cell RNA - MOLT-4 [nTPM]":"47.0","Cell RNA - NB-4 [nTPM]":"110.9","Cell RNA - NTERA-2 [nTPM]":"153.1","Cell RNA - OE19 [nTPM]":"719.7","Cell RNA - PC-3 [nTPM]":"247.9","Cell RNA - REH [nTPM]":"62.5","Cell RNA - RH-30 [nTPM]":"72.5","Cell RNA - RPMI-8226 [nTPM]":"191.2","Cell RNA - RPTEC TERT1 [nTPM]":"586.6","Cell RNA - RT4 [nTPM]":"610.8","Cell RNA - SCLC-21H [nTPM]":"84.2","Cell RNA - SH-SY5Y [nTPM]":"94.8","Cell RNA - SiHa [nTPM]":"173.3","Cell RNA - SK-BR-3 [nTPM]":"2488.5","Cell RNA - SK-MEL-30 [nTPM]":"535.0","Cell RNA - SuSa [nTPM]":"68.6","Cell RNA - T-47d [nTPM]":"1022.8","Cell RNA - THP-1 [nTPM]":"232.6","Cell RNA - TIME [nTPM]":"170.3","Cell RNA - U-138 MG [nTPM]":"556.8","Cell RNA - U-2 OS [nTPM]":"92.9","Cell RNA - U-2197 [nTPM]":"79.0","Cell RNA - U-251 MG [nTPM]":"216.7","Cell RNA - U-266\/70 [nTPM]":"432.0","Cell RNA - U-266\/84 [nTPM]":"382.3","Cell RNA - U-698 [nTPM]":"26.8","Cell RNA - U-87 MG [nTPM]":"867.7","Cell RNA - U-937 [nTPM]":"468.6","Cell RNA - WM-115 [nTPM]":"509.6","Blood RNA - basophil [nTPM]":"211.2","Blood RNA - classical monocyte [nTPM]":"578.7","Blood RNA - eosinophil [nTPM]":"170.1","Blood RNA - gdT-cell [nTPM]":"156.5","Blood RNA - intermediate monocyte [nTPM]":"309.9","Blood RNA - MAIT T-cell [nTPM]":"90.6","Blood RNA - memory B-cell [nTPM]":"28.8","Blood RNA - memory CD4 T-cell [nTPM]":"72.1","Blood RNA - memory CD8 T-cell [nTPM]":"110.3","Blood RNA - myeloid DC [nTPM]":"144.5","Blood RNA - naive B-cell [nTPM]":"18.8","Blood RNA - naive CD4 T-cell [nTPM]":"82.5","Blood RNA - naive CD8 T-cell [nTPM]":"107.4","Blood RNA - neutrophil [nTPM]":"319.5","Blood RNA - NK-cell [nTPM]":"192.3","Blood RNA - non-classical monocyte [nTPM]":"265.2","Blood RNA - plasmacytoid DC [nTPM]":"120.3","Blood RNA - T-reg [nTPM]":"89.2","Blood RNA - total PBMC [nTPM]":"489.1","Brain RNA - amygdala [nTPM]":"147.0","Brain RNA - basal ganglia [nTPM]":"181.9","Brain RNA - cerebellum [nTPM]":"186.0","Brain RNA - cerebral cortex [nTPM]":"156.5","Brain RNA - hippocampal formation [nTPM]":"187.8","Brain RNA - hypothalamus [nTPM]":"223.6","Brain RNA - medulla oblongata [nTPM]":"247.6","Brain RNA - midbrain [nTPM]":"206.6","Brain RNA - pons [nTPM]":"228.6","Brain RNA - spinal cord [nTPM]":"188.9","Brain RNA - thalamus [nTPM]":"334.4","Brain RNA - white matter [nTPM]":"367.1","Single Cell Type RNA - Adipocytes [nTPM]":"139.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"112.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"228.6","Single Cell Type RNA - Astrocytes [nTPM]":"48.3","Single Cell Type RNA - B-cells [nTPM]":"62.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"72.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"223.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"473.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"71.7","Single Cell Type RNA - Bipolar cells [nTPM]":"168.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"108.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"113.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"251.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"314.5","Single Cell Type RNA - Club cells [nTPM]":"459.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"548.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"110.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"211.7","Single Cell Type RNA - dendritic cells [nTPM]":"156.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"1475.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"109.5","Single Cell Type RNA - Ductal cells [nTPM]":"911.4","Single Cell Type RNA - Early spermatids [nTPM]":"3.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"118.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"67.4","Single Cell Type RNA - Endothelial cells [nTPM]":"128.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"159.6","Single Cell Type RNA - Erythroid cells [nTPM]":"132.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"370.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"165.0","Single Cell Type RNA - Fibroblasts [nTPM]":"157.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"237.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"203.4","Single Cell Type RNA - granulocytes [nTPM]":"474.3","Single Cell Type RNA - Granulosa cells [nTPM]":"119.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"695.7","Single Cell Type RNA - Hepatocytes [nTPM]":"678.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"3763.5","Single Cell Type RNA - Horizontal cells [nTPM]":"264.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"418.2","Single Cell Type RNA - Ionocytes [nTPM]":"498.5","Single Cell Type RNA - Kupffer cells [nTPM]":"1187.8","Single Cell Type RNA - Langerhans cells [nTPM]":"67.5","Single Cell Type RNA - Late spermatids [nTPM]":"14.6","Single Cell Type RNA - Leydig cells [nTPM]":"108.4","Single Cell Type RNA - Macrophages [nTPM]":"1512.6","Single Cell Type RNA - Melanocytes [nTPM]":"227.7","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"382.6","Single Cell Type RNA - Muller glia cells [nTPM]":"179.0","Single Cell Type RNA - NK-cells [nTPM]":"256.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"27.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"42.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"392.3","Single Cell Type RNA - Paneth cells [nTPM]":"832.5","Single Cell Type RNA - Peritubular cells [nTPM]":"128.2","Single Cell Type RNA - Plasma cells [nTPM]":"122.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"111.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1699.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"311.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"270.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"102.1","Single Cell Type RNA - Sertoli cells [nTPM]":"111.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"70.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"135.2","Single Cell Type RNA - Spermatocytes [nTPM]":"26.6","Single Cell Type RNA - Spermatogonia [nTPM]":"63.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"141.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"82.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"471.3","Single Cell Type RNA - T-cells [nTPM]":"155.0","Single Cell Type RNA - Theca cells [nTPM]":"96.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"399.1","Single Cell Type RNA - Urothelial cells [nTPM]":"357.8"},{"Gene":"CTSF","Gene synonym":["CATSF","CLN13"],"Ensembl":"ENSG00000174080","Gene description":"Cathepsin F","Uniprot":["Q9UBX1"],"Chromosome":"11","Position":"66563464-66568879","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Disease variant","Neurodegeneration","Neuronal ceroid lipofuscinosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"320.9","Muller glia cells":"196.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SiHa":"23.1","SK-MEL-30":"59.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002141","HPA031431"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Vesicles","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5800000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 5: Muller glia cells - Visual perception","Subcellular main location":["Vesicles"],"Subcellular additional location":["Endoplasmic reticulum","Plasma membrane"],"Antibody RRID":{"CAB002141":"AB_563471","HPA031431":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.92e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Tissue RNA - adipose tissue [nTPM]":"57.8","Tissue RNA - adrenal gland [nTPM]":"70.0","Tissue RNA - amygdala [nTPM]":"68.1","Tissue RNA - appendix [nTPM]":"0.8","Tissue RNA - basal ganglia [nTPM]":"76.3","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"62.2","Tissue RNA - cerebellum [nTPM]":"74.5","Tissue RNA - cerebral cortex [nTPM]":"74.0","Tissue RNA - cervix [nTPM]":"78.8","Tissue RNA - choroid plexus [nTPM]":"90.2","Tissue RNA - colon [nTPM]":"76.7","Tissue RNA - duodenum [nTPM]":"3.0","Tissue RNA - endometrium 1 [nTPM]":"89.2","Tissue RNA - epididymis [nTPM]":"21.9","Tissue RNA - esophagus [nTPM]":"15.6","Tissue RNA - fallopian tube [nTPM]":"70.8","Tissue RNA - gallbladder [nTPM]":"10.0","Tissue RNA - heart muscle [nTPM]":"100.2","Tissue RNA - hippocampal formation [nTPM]":"63.2","Tissue RNA - hypothalamus [nTPM]":"74.2","Tissue RNA - kidney [nTPM]":"46.9","Tissue RNA - liver [nTPM]":"66.0","Tissue RNA - lung [nTPM]":"32.9","Tissue RNA - lymph node [nTPM]":"3.6","Tissue RNA - medulla oblongata [nTPM]":"75.0","Tissue RNA - midbrain [nTPM]":"70.3","Tissue RNA - ovary [nTPM]":"99.1","Tissue RNA - pancreas [nTPM]":"31.7","Tissue RNA - parathyroid gland [nTPM]":"20.0","Tissue RNA - pituitary gland [nTPM]":"43.3","Tissue RNA - placenta [nTPM]":"3.8","Tissue RNA - pons [nTPM]":"68.4","Tissue RNA - prostate [nTPM]":"53.5","Tissue RNA - rectum [nTPM]":"3.5","Tissue RNA - retina [nTPM]":"26.2","Tissue RNA - salivary gland [nTPM]":"55.7","Tissue RNA - seminal vesicle [nTPM]":"17.1","Tissue RNA - skeletal muscle [nTPM]":"91.9","Tissue RNA - skin 1 [nTPM]":"44.4","Tissue RNA - small intestine [nTPM]":"29.5","Tissue RNA - smooth muscle [nTPM]":"12.2","Tissue RNA - spinal cord [nTPM]":"77.2","Tissue RNA - spleen [nTPM]":"25.0","Tissue RNA - stomach 1 [nTPM]":"54.3","Tissue RNA - testis [nTPM]":"109.7","Tissue RNA - thalamus [nTPM]":"71.0","Tissue RNA - thymus [nTPM]":"3.0","Tissue RNA - thyroid gland [nTPM]":"40.6","Tissue RNA - tongue [nTPM]":"27.6","Tissue RNA - tonsil [nTPM]":"3.0","Tissue RNA - urinary bladder [nTPM]":"56.6","Tissue RNA - vagina [nTPM]":"58.7","Tissue RNA - white matter [nTPM]":"86.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"17.0","Cell RNA - AF22 [nTPM]":"3.1","Cell RNA - AN3-CA [nTPM]":"5.4","Cell RNA - ASC diff [nTPM]":"14.2","Cell RNA - ASC TERT1 [nTPM]":"8.6","Cell RNA - BEWO [nTPM]":"3.4","Cell RNA - BJ [nTPM]":"13.0","Cell RNA - BJ hTERT+ [nTPM]":"11.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.3","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"2.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"21.3","Cell RNA - fHDF\/TERT166 [nTPM]":"10.4","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"1.2","Cell RNA - HAP1 [nTPM]":"6.8","Cell RNA - HBEC3-KT [nTPM]":"2.6","Cell RNA - HBF TERT88 [nTPM]":"4.8","Cell RNA - HDLM-2 [nTPM]":"3.7","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.5","Cell RNA - HeLa [nTPM]":"7.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"9.9","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"4.4","Cell RNA - HSkMC [nTPM]":"22.3","Cell RNA - hTCEpi [nTPM]":"9.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.8","Cell RNA - hTERT-HME1 [nTPM]":"1.6","Cell RNA - hTERT-RPE1 [nTPM]":"13.7","Cell RNA - HUVEC TERT2 [nTPM]":"3.8","Cell RNA - JURKAT [nTPM]":"2.0","Cell RNA - K-562 [nTPM]":"5.4","Cell RNA - Karpas-707 [nTPM]":"1.6","Cell RNA - LHCN-M2 [nTPM]":"5.2","Cell RNA - MCF7 [nTPM]":"4.6","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"1.7","Cell RNA - NTERA-2 [nTPM]":"0.9","Cell RNA - OE19 [nTPM]":"3.7","Cell RNA - PC-3 [nTPM]":"9.7","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.5","Cell RNA - RPTEC TERT1 [nTPM]":"7.1","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"4.3","Cell RNA - SH-SY5Y [nTPM]":"6.9","Cell RNA - SiHa [nTPM]":"23.1","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"59.5","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"7.4","Cell RNA - THP-1 [nTPM]":"0.6","Cell RNA - TIME [nTPM]":"3.3","Cell RNA - U-138 MG [nTPM]":"1.8","Cell RNA - U-2 OS [nTPM]":"2.9","Cell RNA - U-2197 [nTPM]":"1.5","Cell RNA - U-251 MG [nTPM]":"1.2","Cell RNA - U-266\/70 [nTPM]":"21.2","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"2.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"2.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"3.9","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"4.1","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"3.5","Blood RNA - memory CD8 T-cell [nTPM]":"4.6","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"1.4","Blood RNA - naive CD4 T-cell [nTPM]":"6.4","Blood RNA - naive CD8 T-cell [nTPM]":"4.1","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"4.6","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"1.3","Blood RNA - total PBMC [nTPM]":"2.2","Brain RNA - amygdala [nTPM]":"68.1","Brain RNA - basal ganglia [nTPM]":"76.3","Brain RNA - cerebellum [nTPM]":"74.5","Brain RNA - cerebral cortex [nTPM]":"74.0","Brain RNA - hippocampal formation [nTPM]":"63.2","Brain RNA - hypothalamus [nTPM]":"74.2","Brain RNA - medulla oblongata [nTPM]":"75.0","Brain RNA - midbrain [nTPM]":"70.3","Brain RNA - pons [nTPM]":"68.4","Brain RNA - spinal cord [nTPM]":"77.2","Brain RNA - thalamus [nTPM]":"71.0","Brain RNA - white matter [nTPM]":"86.6","Single Cell Type RNA - Adipocytes [nTPM]":"36.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.6","Single Cell Type RNA - Astrocytes [nTPM]":"31.3","Single Cell Type RNA - B-cells [nTPM]":"5.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"39.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"62.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"37.5","Single Cell Type RNA - Bipolar cells [nTPM]":"107.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"45.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"80.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"57.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"41.5","Single Cell Type RNA - Club cells [nTPM]":"7.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"31.6","Single Cell Type RNA - dendritic cells [nTPM]":"9.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"13.1","Single Cell Type RNA - Early spermatids [nTPM]":"163.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.8","Single Cell Type RNA - Endothelial cells [nTPM]":"27.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.0","Single Cell Type RNA - Erythroid cells [nTPM]":"11.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"26.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.5","Single Cell Type RNA - Fibroblasts [nTPM]":"118.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.3","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"52.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"56.0","Single Cell Type RNA - Hepatocytes [nTPM]":"67.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.9","Single Cell Type RNA - Horizontal cells [nTPM]":"134.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"31.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.1","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"21.5","Single Cell Type RNA - Langerhans cells [nTPM]":"32.8","Single Cell Type RNA - Late spermatids [nTPM]":"320.9","Single Cell Type RNA - Leydig cells [nTPM]":"145.7","Single Cell Type RNA - Macrophages [nTPM]":"13.1","Single Cell Type RNA - Melanocytes [nTPM]":"156.5","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"3.1","Single Cell Type RNA - Muller glia cells [nTPM]":"196.6","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"29.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.9","Single Cell Type RNA - Paneth cells [nTPM]":"3.2","Single Cell Type RNA - Peritubular cells [nTPM]":"121.9","Single Cell Type RNA - Plasma cells [nTPM]":"12.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"50.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"44.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"77.9","Single Cell Type RNA - Sertoli cells [nTPM]":"78.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"62.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"45.9","Single Cell Type RNA - Spermatocytes [nTPM]":"169.6","Single Cell Type RNA - Spermatogonia [nTPM]":"43.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"25.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.7","Single Cell Type RNA - T-cells [nTPM]":"9.5","Single Cell Type RNA - Theca cells [nTPM]":"30.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.3","Single Cell Type RNA - Urothelial cells [nTPM]":"32.9"},{"Gene":"CTSK","Gene synonym":["CTSO","CTSO2","PKND","PYCD"],"Ensembl":"ENSG00000143387","Gene description":"Cathepsin K","Uniprot":["P43235"],"Chromosome":"1","Position":"150794880-150809577","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"420.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Fibroblasts":"372.4","Langerhans cells":"123.6","Leydig cells":"119.0","Melanocytes":"97.8","Peritubular cells":"149.7","Theca cells":"80.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"cerebral cortex":"18.1"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"1.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"monocytes":"1.8"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"ASC diff":"2284.0","ASC TERT1":"813.2","BJ hTERT+":"1949.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050346"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA050346":"AB_2681101"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.61e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.12e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Tissue RNA - adipose tissue [nTPM]":"224.1","Tissue RNA - adrenal gland [nTPM]":"12.5","Tissue RNA - amygdala [nTPM]":"2.7","Tissue RNA - appendix [nTPM]":"33.1","Tissue RNA - basal ganglia [nTPM]":"2.8","Tissue RNA - bone marrow [nTPM]":"3.1","Tissue RNA - breast [nTPM]":"227.7","Tissue RNA - cerebellum [nTPM]":"2.9","Tissue RNA - cerebral cortex [nTPM]":"18.1","Tissue RNA - cervix [nTPM]":"420.6","Tissue RNA - choroid plexus [nTPM]":"16.4","Tissue RNA - colon [nTPM]":"68.6","Tissue RNA - duodenum [nTPM]":"13.8","Tissue RNA - endometrium 1 [nTPM]":"334.0","Tissue RNA - epididymis [nTPM]":"44.9","Tissue RNA - esophagus [nTPM]":"46.0","Tissue RNA - fallopian tube [nTPM]":"74.0","Tissue RNA - gallbladder [nTPM]":"299.2","Tissue RNA - heart muscle [nTPM]":"35.8","Tissue RNA - hippocampal formation [nTPM]":"2.7","Tissue RNA - hypothalamus [nTPM]":"2.6","Tissue RNA - kidney [nTPM]":"12.7","Tissue RNA - liver [nTPM]":"9.0","Tissue RNA - lung [nTPM]":"36.4","Tissue RNA - lymph node [nTPM]":"42.1","Tissue RNA - medulla oblongata [nTPM]":"2.7","Tissue RNA - midbrain [nTPM]":"2.7","Tissue RNA - ovary [nTPM]":"78.4","Tissue RNA - pancreas [nTPM]":"10.6","Tissue RNA - parathyroid gland [nTPM]":"6.1","Tissue RNA - pituitary gland [nTPM]":"14.6","Tissue RNA - placenta [nTPM]":"18.9","Tissue RNA - pons [nTPM]":"2.6","Tissue RNA - prostate [nTPM]":"34.1","Tissue RNA - rectum [nTPM]":"61.8","Tissue RNA - retina [nTPM]":"6.9","Tissue RNA - salivary gland [nTPM]":"53.3","Tissue RNA - seminal vesicle [nTPM]":"38.0","Tissue RNA - skeletal muscle [nTPM]":"15.7","Tissue RNA - skin 1 [nTPM]":"219.8","Tissue RNA - small intestine [nTPM]":"63.8","Tissue RNA - smooth muscle [nTPM]":"141.6","Tissue RNA - spinal cord [nTPM]":"2.8","Tissue RNA - spleen [nTPM]":"20.2","Tissue RNA - stomach 1 [nTPM]":"41.7","Tissue RNA - testis [nTPM]":"15.1","Tissue RNA - thalamus [nTPM]":"2.7","Tissue RNA - thymus [nTPM]":"12.3","Tissue RNA - thyroid gland [nTPM]":"34.7","Tissue RNA - tongue [nTPM]":"46.3","Tissue RNA - tonsil [nTPM]":"48.7","Tissue RNA - urinary bladder [nTPM]":"210.5","Tissue RNA - vagina [nTPM]":"176.2","Tissue RNA - white matter [nTPM]":"2.9","Cell RNA - A-431 [nTPM]":"0.7","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"1.4","Cell RNA - AN3-CA [nTPM]":"0.8","Cell RNA - ASC diff [nTPM]":"2284.0","Cell RNA - ASC TERT1 [nTPM]":"813.2","Cell RNA - BEWO [nTPM]":"1.0","Cell RNA - BJ [nTPM]":"55.2","Cell RNA - BJ hTERT+ [nTPM]":"1949.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.3","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"0.6","Cell RNA - fHDF\/TERT166 [nTPM]":"129.8","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.6","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"1.2","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"1.4","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"11.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"1.3","Cell RNA - HSkMC [nTPM]":"156.5","Cell RNA - hTCEpi [nTPM]":"1.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"50.5","Cell RNA - hTERT-HME1 [nTPM]":"0.7","Cell RNA - hTERT-RPE1 [nTPM]":"137.6","Cell RNA - HUVEC TERT2 [nTPM]":"4.2","Cell RNA - JURKAT [nTPM]":"0.6","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"1.4","Cell RNA - LHCN-M2 [nTPM]":"1.5","Cell RNA - MCF7 [nTPM]":"1.4","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"3.0","Cell RNA - NTERA-2 [nTPM]":"10.2","Cell RNA - OE19 [nTPM]":"1.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"3.2","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"2.9","Cell RNA - SiHa [nTPM]":"0.4","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"29.3","Cell RNA - SuSa [nTPM]":"3.9","Cell RNA - T-47d [nTPM]":"1.0","Cell RNA - THP-1 [nTPM]":"1.5","Cell RNA - TIME [nTPM]":"1.0","Cell RNA - U-138 MG [nTPM]":"0.7","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.6","Cell RNA - U-251 MG [nTPM]":"0.6","Cell RNA - U-266\/70 [nTPM]":"2.3","Cell RNA - U-266\/84 [nTPM]":"1.7","Cell RNA - U-698 [nTPM]":"3.6","Cell RNA - U-87 MG [nTPM]":"184.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"9.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.8","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"2.7","Brain RNA - basal ganglia [nTPM]":"2.8","Brain RNA - cerebellum [nTPM]":"2.9","Brain RNA - cerebral cortex [nTPM]":"18.1","Brain RNA - hippocampal formation [nTPM]":"2.7","Brain RNA - hypothalamus [nTPM]":"2.6","Brain RNA - medulla oblongata [nTPM]":"2.7","Brain RNA - midbrain [nTPM]":"2.7","Brain RNA - pons [nTPM]":"2.6","Brain RNA - spinal cord [nTPM]":"2.8","Brain RNA - thalamus [nTPM]":"2.7","Brain RNA - white matter [nTPM]":"2.9","Single Cell Type RNA - Adipocytes [nTPM]":"17.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.6","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"68.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"12.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"3.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.3","Single Cell Type RNA - dendritic cells [nTPM]":"2.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"59.0","Single Cell Type RNA - Endothelial cells [nTPM]":"10.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.5","Single Cell Type RNA - Fibroblasts [nTPM]":"372.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"77.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"21.4","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.6","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"4.6","Single Cell Type RNA - Langerhans cells [nTPM]":"123.6","Single Cell Type RNA - Late spermatids [nTPM]":"4.4","Single Cell Type RNA - Leydig cells [nTPM]":"119.0","Single Cell Type RNA - Macrophages [nTPM]":"8.7","Single Cell Type RNA - Melanocytes [nTPM]":"97.8","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"4.9","Single Cell Type RNA - Muller glia cells [nTPM]":"2.7","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.4","Single Cell Type RNA - Paneth cells [nTPM]":"1.4","Single Cell Type RNA - Peritubular cells [nTPM]":"149.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"33.9","Single Cell Type RNA - Spermatocytes [nTPM]":"1.4","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"59.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"5.4","Single Cell Type RNA - Theca cells [nTPM]":"80.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"CX3CR1","Gene synonym":["CCRL1","CMKBRL1","CMKDR1","GPR13","V28"],"Ensembl":"ENSG00000168329","Gene description":"C-X3-C motif chemokine receptor 1","Uniprot":["P49238"],"Chromosome":"3","Position":"39263495-39281735","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity","Inflammatory response","Innate immunity"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Age-related macular degeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"26.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Microglial cells":"177.1","NK-cells":"350.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"21.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"449.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"21","RNA cell line specific nTPM":{"RPMI-8226":"589.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB032478","HPA046587"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB032478":"AB_638830","HPA046587":"AB_2679708"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.71e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Tissue RNA - adipose tissue [nTPM]":"2.3","Tissue RNA - adrenal gland [nTPM]":"3.8","Tissue RNA - amygdala [nTPM]":"6.2","Tissue RNA - appendix [nTPM]":"6.9","Tissue RNA - basal ganglia [nTPM]":"6.4","Tissue RNA - bone marrow [nTPM]":"1.1","Tissue RNA - breast [nTPM]":"5.1","Tissue RNA - cerebellum [nTPM]":"8.6","Tissue RNA - cerebral cortex [nTPM]":"6.0","Tissue RNA - cervix [nTPM]":"2.7","Tissue RNA - choroid plexus [nTPM]":"1.7","Tissue RNA - colon [nTPM]":"1.1","Tissue RNA - duodenum [nTPM]":"1.2","Tissue RNA - endometrium 1 [nTPM]":"2.7","Tissue RNA - epididymis [nTPM]":"4.2","Tissue RNA - esophagus [nTPM]":"0.8","Tissue RNA - fallopian tube [nTPM]":"6.1","Tissue RNA - gallbladder [nTPM]":"2.6","Tissue RNA - heart muscle [nTPM]":"2.4","Tissue RNA - hippocampal formation [nTPM]":"7.7","Tissue RNA - hypothalamus [nTPM]":"8.4","Tissue RNA - kidney [nTPM]":"2.5","Tissue RNA - liver [nTPM]":"2.0","Tissue RNA - lung [nTPM]":"9.9","Tissue RNA - lymph node [nTPM]":"2.1","Tissue RNA - medulla oblongata [nTPM]":"17.3","Tissue RNA - midbrain [nTPM]":"14.8","Tissue RNA - ovary [nTPM]":"1.6","Tissue RNA - pancreas [nTPM]":"0.7","Tissue RNA - parathyroid gland [nTPM]":"4.5","Tissue RNA - pituitary gland [nTPM]":"1.0","Tissue RNA - placenta [nTPM]":"4.6","Tissue RNA - pons [nTPM]":"18.9","Tissue RNA - prostate [nTPM]":"3.5","Tissue RNA - rectum [nTPM]":"1.1","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"7.6","Tissue RNA - seminal vesicle [nTPM]":"7.2","Tissue RNA - skeletal muscle [nTPM]":"6.5","Tissue RNA - skin 1 [nTPM]":"2.3","Tissue RNA - small intestine [nTPM]":"0.9","Tissue RNA - smooth muscle [nTPM]":"3.5","Tissue RNA - spinal cord [nTPM]":"21.5","Tissue RNA - spleen [nTPM]":"11.9","Tissue RNA - stomach 1 [nTPM]":"1.4","Tissue RNA - testis [nTPM]":"1.8","Tissue RNA - thalamus [nTPM]":"17.4","Tissue RNA - thymus [nTPM]":"2.0","Tissue RNA - thyroid gland [nTPM]":"2.4","Tissue RNA - tongue [nTPM]":"2.2","Tissue RNA - tonsil [nTPM]":"5.3","Tissue RNA - urinary bladder [nTPM]":"2.4","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"26.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.4","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"1.5","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"6.8","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.8","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"24.5","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"589.8","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"8.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"16.5","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"1.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"28.6","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"7.7","Blood RNA - classical monocyte [nTPM]":"99.6","Blood RNA - eosinophil [nTPM]":"1.8","Blood RNA - gdT-cell [nTPM]":"264.0","Blood RNA - intermediate monocyte [nTPM]":"261.2","Blood RNA - MAIT T-cell [nTPM]":"3.4","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"55.9","Blood RNA - memory CD8 T-cell [nTPM]":"145.2","Blood RNA - myeloid DC [nTPM]":"94.4","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"19.0","Blood RNA - naive CD8 T-cell [nTPM]":"122.4","Blood RNA - neutrophil [nTPM]":"20.8","Blood RNA - NK-cell [nTPM]":"39.7","Blood RNA - non-classical monocyte [nTPM]":"449.2","Blood RNA - plasmacytoid DC [nTPM]":"7.1","Blood RNA - T-reg [nTPM]":"1.5","Blood RNA - total PBMC [nTPM]":"232.7","Brain RNA - amygdala [nTPM]":"6.2","Brain RNA - basal ganglia [nTPM]":"6.4","Brain RNA - cerebellum [nTPM]":"8.6","Brain RNA - cerebral cortex [nTPM]":"6.0","Brain RNA - hippocampal formation [nTPM]":"7.7","Brain RNA - hypothalamus [nTPM]":"8.4","Brain RNA - medulla oblongata [nTPM]":"17.3","Brain RNA - midbrain [nTPM]":"14.8","Brain RNA - pons [nTPM]":"18.9","Brain RNA - spinal cord [nTPM]":"21.5","Brain RNA - thalamus [nTPM]":"17.4","Brain RNA - white matter [nTPM]":"26.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"44.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"3.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"15.0","Single Cell Type RNA - Langerhans cells [nTPM]":"28.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"43.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"177.1","Single Cell Type RNA - monocytes [nTPM]":"50.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"350.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"22.6","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CYB561","Gene synonym":["CYB561A1","FRRS2"],"Ensembl":"ENSG00000008283","Gene description":"Cytochrome b561","Uniprot":["P49447"],"Chromosome":"17","Position":"63432304-63446354","Protein class":["Disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Electron transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"74.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"pons":"124.7"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SH-SY5Y":"432.2","SK-BR-3":"209.2","T-47d":"168.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014753"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014753":"AB_1847364"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.89e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.95e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Tissue RNA - adipose tissue [nTPM]":"14.8","Tissue RNA - adrenal gland [nTPM]":"125.6","Tissue RNA - amygdala [nTPM]":"22.2","Tissue RNA - appendix [nTPM]":"12.3","Tissue RNA - basal ganglia [nTPM]":"24.4","Tissue RNA - bone marrow [nTPM]":"4.1","Tissue RNA - breast [nTPM]":"32.8","Tissue RNA - cerebellum [nTPM]":"6.8","Tissue RNA - cerebral cortex [nTPM]":"23.1","Tissue RNA - cervix [nTPM]":"45.0","Tissue RNA - choroid plexus [nTPM]":"70.6","Tissue RNA - colon [nTPM]":"26.4","Tissue RNA - duodenum [nTPM]":"36.6","Tissue RNA - endometrium 1 [nTPM]":"12.3","Tissue RNA - epididymis [nTPM]":"57.2","Tissue RNA - esophagus [nTPM]":"51.9","Tissue RNA - fallopian tube [nTPM]":"55.8","Tissue RNA - gallbladder [nTPM]":"17.3","Tissue RNA - heart muscle [nTPM]":"16.2","Tissue RNA - hippocampal formation [nTPM]":"20.4","Tissue RNA - hypothalamus [nTPM]":"33.2","Tissue RNA - kidney [nTPM]":"24.5","Tissue RNA - liver [nTPM]":"21.0","Tissue RNA - lung [nTPM]":"30.9","Tissue RNA - lymph node [nTPM]":"8.3","Tissue RNA - medulla oblongata [nTPM]":"17.2","Tissue RNA - midbrain [nTPM]":"23.2","Tissue RNA - ovary [nTPM]":"9.4","Tissue RNA - pancreas [nTPM]":"118.0","Tissue RNA - parathyroid gland [nTPM]":"76.1","Tissue RNA - pituitary gland [nTPM]":"74.1","Tissue RNA - placenta [nTPM]":"16.2","Tissue RNA - pons [nTPM]":"124.7","Tissue RNA - prostate [nTPM]":"63.3","Tissue RNA - rectum [nTPM]":"21.1","Tissue RNA - retina [nTPM]":"9.8","Tissue RNA - salivary gland [nTPM]":"85.0","Tissue RNA - seminal vesicle [nTPM]":"37.8","Tissue RNA - skeletal muscle [nTPM]":"6.0","Tissue RNA - skin 1 [nTPM]":"37.3","Tissue RNA - small intestine [nTPM]":"31.9","Tissue RNA - smooth muscle [nTPM]":"9.2","Tissue RNA - spinal cord [nTPM]":"9.8","Tissue RNA - spleen [nTPM]":"8.7","Tissue RNA - stomach 1 [nTPM]":"48.1","Tissue RNA - testis [nTPM]":"6.0","Tissue RNA - thalamus [nTPM]":"28.0","Tissue RNA - thymus [nTPM]":"3.5","Tissue RNA - thyroid gland [nTPM]":"40.8","Tissue RNA - tongue [nTPM]":"4.6","Tissue RNA - tonsil [nTPM]":"12.8","Tissue RNA - urinary bladder [nTPM]":"16.4","Tissue RNA - vagina [nTPM]":"27.4","Tissue RNA - white matter [nTPM]":"17.9","Cell RNA - A-431 [nTPM]":"99.3","Cell RNA - A549 [nTPM]":"31.9","Cell RNA - AF22 [nTPM]":"2.6","Cell RNA - AN3-CA [nTPM]":"20.5","Cell RNA - ASC diff [nTPM]":"11.5","Cell RNA - ASC TERT1 [nTPM]":"52.7","Cell RNA - BEWO [nTPM]":"43.3","Cell RNA - BJ [nTPM]":"10.3","Cell RNA - BJ hTERT+ [nTPM]":"12.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.9","Cell RNA - CACO-2 [nTPM]":"29.2","Cell RNA - CAPAN-2 [nTPM]":"96.9","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"23.0","Cell RNA - fHDF\/TERT166 [nTPM]":"75.5","Cell RNA - GAMG [nTPM]":"3.3","Cell RNA - HaCaT [nTPM]":"83.1","Cell RNA - HAP1 [nTPM]":"20.3","Cell RNA - HBEC3-KT [nTPM]":"8.0","Cell RNA - HBF TERT88 [nTPM]":"4.8","Cell RNA - HDLM-2 [nTPM]":"26.1","Cell RNA - HEK 293 [nTPM]":"8.7","Cell RNA - HEL [nTPM]":"12.7","Cell RNA - HeLa [nTPM]":"20.4","Cell RNA - Hep G2 [nTPM]":"2.0","Cell RNA - HHSteC [nTPM]":"21.7","Cell RNA - HL-60 [nTPM]":"1.3","Cell RNA - HMC-1 [nTPM]":"4.3","Cell RNA - HSkMC [nTPM]":"8.6","Cell RNA - hTCEpi [nTPM]":"84.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.2","Cell RNA - hTERT-HME1 [nTPM]":"1.5","Cell RNA - hTERT-RPE1 [nTPM]":"17.9","Cell RNA - HUVEC TERT2 [nTPM]":"23.9","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"41.2","Cell RNA - Karpas-707 [nTPM]":"17.7","Cell RNA - LHCN-M2 [nTPM]":"4.0","Cell RNA - MCF7 [nTPM]":"140.3","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"4.9","Cell RNA - NTERA-2 [nTPM]":"20.9","Cell RNA - OE19 [nTPM]":"80.5","Cell RNA - PC-3 [nTPM]":"49.9","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"31.0","Cell RNA - RPTEC TERT1 [nTPM]":"40.0","Cell RNA - RT4 [nTPM]":"49.8","Cell RNA - SCLC-21H [nTPM]":"73.7","Cell RNA - SH-SY5Y [nTPM]":"432.2","Cell RNA - SiHa [nTPM]":"26.0","Cell RNA - SK-BR-3 [nTPM]":"209.2","Cell RNA - SK-MEL-30 [nTPM]":"10.4","Cell RNA - SuSa [nTPM]":"7.3","Cell RNA - T-47d [nTPM]":"168.6","Cell RNA - THP-1 [nTPM]":"6.2","Cell RNA - TIME [nTPM]":"3.6","Cell RNA - U-138 MG [nTPM]":"25.9","Cell RNA - U-2 OS [nTPM]":"29.4","Cell RNA - U-2197 [nTPM]":"60.6","Cell RNA - U-251 MG [nTPM]":"3.1","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"22.6","Cell RNA - U-937 [nTPM]":"5.1","Cell RNA - WM-115 [nTPM]":"14.0","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"2.0","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"19.2","Blood RNA - intermediate monocyte [nTPM]":"5.7","Blood RNA - MAIT T-cell [nTPM]":"24.6","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"14.4","Blood RNA - memory CD8 T-cell [nTPM]":"13.2","Blood RNA - myeloid DC [nTPM]":"2.1","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"4.2","Blood RNA - neutrophil [nTPM]":"5.2","Blood RNA - NK-cell [nTPM]":"20.3","Blood RNA - non-classical monocyte [nTPM]":"7.7","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"5.8","Brain RNA - amygdala [nTPM]":"22.2","Brain RNA - basal ganglia [nTPM]":"24.4","Brain RNA - cerebellum [nTPM]":"6.8","Brain RNA - cerebral cortex [nTPM]":"23.1","Brain RNA - hippocampal formation [nTPM]":"20.4","Brain RNA - hypothalamus [nTPM]":"33.2","Brain RNA - medulla oblongata [nTPM]":"17.2","Brain RNA - midbrain [nTPM]":"23.2","Brain RNA - pons [nTPM]":"124.7","Brain RNA - spinal cord [nTPM]":"9.8","Brain RNA - thalamus [nTPM]":"28.0","Brain RNA - white matter [nTPM]":"17.9","Single Cell Type RNA - Adipocytes [nTPM]":"14.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"37.8","Single Cell Type RNA - Astrocytes [nTPM]":"3.6","Single Cell Type RNA - B-cells [nTPM]":"3.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.2","Single Cell Type RNA - Bipolar cells [nTPM]":"6.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"37.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"36.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.1","Single Cell Type RNA - dendritic cells [nTPM]":"7.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"22.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"41.1","Single Cell Type RNA - Early spermatids [nTPM]":"6.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"74.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.5","Single Cell Type RNA - Endothelial cells [nTPM]":"18.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.6","Single Cell Type RNA - Erythroid cells [nTPM]":"3.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"50.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"29.2","Single Cell Type RNA - Fibroblasts [nTPM]":"15.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"30.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"53.9","Single Cell Type RNA - granulocytes [nTPM]":"15.9","Single Cell Type RNA - Granulosa cells [nTPM]":"7.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.4","Single Cell Type RNA - Hepatocytes [nTPM]":"11.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.7","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"7.0","Single Cell Type RNA - Langerhans cells [nTPM]":"9.8","Single Cell Type RNA - Late spermatids [nTPM]":"6.2","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"4.1","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"6.0","Single Cell Type RNA - Muller glia cells [nTPM]":"5.2","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"30.8","Single Cell Type RNA - Paneth cells [nTPM]":"11.4","Single Cell Type RNA - Peritubular cells [nTPM]":"3.4","Single Cell Type RNA - Plasma cells [nTPM]":"15.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"41.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"32.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"68.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"26.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.6","Single Cell Type RNA - Spermatocytes [nTPM]":"6.9","Single Cell Type RNA - Spermatogonia [nTPM]":"7.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"34.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"24.8","Single Cell Type RNA - T-cells [nTPM]":"11.4","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.2","Single Cell Type RNA - Urothelial cells [nTPM]":"22.6"},{"Gene":"CYB5R3","Gene synonym":["DIA1"],"Ensembl":"ENSG00000100243","Gene description":"Cytochrome b5 reductase 3","Uniprot":["P00387"],"Chromosome":"22","Position":"42617840-42649392","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"830.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001566"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1500000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA001566":"AB_1078601"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.13e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Tissue RNA - adipose tissue [nTPM]":"404.4","Tissue RNA - adrenal gland [nTPM]":"310.5","Tissue RNA - amygdala [nTPM]":"147.1","Tissue RNA - appendix [nTPM]":"87.4","Tissue RNA - basal ganglia [nTPM]":"152.9","Tissue RNA - bone marrow [nTPM]":"82.7","Tissue RNA - breast [nTPM]":"272.2","Tissue RNA - cerebellum [nTPM]":"145.7","Tissue RNA - cerebral cortex [nTPM]":"189.9","Tissue RNA - cervix [nTPM]":"237.3","Tissue RNA - choroid plexus [nTPM]":"115.0","Tissue RNA - colon [nTPM]":"192.4","Tissue RNA - duodenum [nTPM]":"94.8","Tissue RNA - endometrium 1 [nTPM]":"248.4","Tissue RNA - epididymis [nTPM]":"58.8","Tissue RNA - esophagus [nTPM]":"152.4","Tissue RNA - fallopian tube [nTPM]":"174.0","Tissue RNA - gallbladder [nTPM]":"139.5","Tissue RNA - heart muscle [nTPM]":"374.3","Tissue RNA - hippocampal formation [nTPM]":"138.7","Tissue RNA - hypothalamus [nTPM]":"163.9","Tissue RNA - kidney [nTPM]":"182.9","Tissue RNA - liver [nTPM]":"279.4","Tissue RNA - lung [nTPM]":"201.3","Tissue RNA - lymph node [nTPM]":"76.3","Tissue RNA - medulla oblongata [nTPM]":"194.7","Tissue RNA - midbrain [nTPM]":"174.2","Tissue RNA - ovary [nTPM]":"218.3","Tissue RNA - pancreas [nTPM]":"89.1","Tissue RNA - parathyroid gland [nTPM]":"62.0","Tissue RNA - pituitary gland [nTPM]":"137.4","Tissue RNA - placenta [nTPM]":"107.8","Tissue RNA - pons [nTPM]":"169.9","Tissue RNA - prostate [nTPM]":"181.4","Tissue RNA - rectum [nTPM]":"74.9","Tissue RNA - retina [nTPM]":"27.3","Tissue RNA - salivary gland [nTPM]":"149.8","Tissue RNA - seminal vesicle [nTPM]":"239.3","Tissue RNA - skeletal muscle [nTPM]":"203.0","Tissue RNA - skin 1 [nTPM]":"233.6","Tissue RNA - small intestine [nTPM]":"138.1","Tissue RNA - smooth muscle [nTPM]":"200.2","Tissue RNA - spinal cord [nTPM]":"154.8","Tissue RNA - spleen [nTPM]":"101.4","Tissue RNA - stomach 1 [nTPM]":"182.0","Tissue RNA - testis [nTPM]":"142.7","Tissue RNA - thalamus [nTPM]":"156.7","Tissue RNA - thymus [nTPM]":"54.0","Tissue RNA - thyroid gland [nTPM]":"157.8","Tissue RNA - tongue [nTPM]":"140.5","Tissue RNA - tonsil [nTPM]":"72.3","Tissue RNA - urinary bladder [nTPM]":"216.7","Tissue RNA - vagina [nTPM]":"210.0","Tissue RNA - white matter [nTPM]":"160.2","Cell RNA - A-431 [nTPM]":"125.5","Cell RNA - A549 [nTPM]":"78.6","Cell RNA - AF22 [nTPM]":"126.6","Cell RNA - AN3-CA [nTPM]":"78.6","Cell RNA - ASC diff [nTPM]":"830.9","Cell RNA - ASC TERT1 [nTPM]":"654.7","Cell RNA - BEWO [nTPM]":"74.4","Cell RNA - BJ [nTPM]":"359.2","Cell RNA - BJ hTERT+ [nTPM]":"330.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"262.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"232.4","Cell RNA - CACO-2 [nTPM]":"104.0","Cell RNA - CAPAN-2 [nTPM]":"95.6","Cell RNA - Daudi [nTPM]":"58.8","Cell RNA - EFO-21 [nTPM]":"156.6","Cell RNA - fHDF\/TERT166 [nTPM]":"668.8","Cell RNA - GAMG [nTPM]":"113.8","Cell RNA - HaCaT [nTPM]":"112.4","Cell RNA - HAP1 [nTPM]":"85.3","Cell RNA - HBEC3-KT [nTPM]":"178.0","Cell RNA - HBF TERT88 [nTPM]":"133.7","Cell RNA - HDLM-2 [nTPM]":"63.9","Cell RNA - HEK 293 [nTPM]":"187.3","Cell RNA - HEL [nTPM]":"83.6","Cell RNA - HeLa [nTPM]":"127.3","Cell RNA - Hep G2 [nTPM]":"202.4","Cell RNA - HHSteC [nTPM]":"211.0","Cell RNA - HL-60 [nTPM]":"118.4","Cell RNA - HMC-1 [nTPM]":"149.5","Cell RNA - HSkMC [nTPM]":"397.4","Cell RNA - hTCEpi [nTPM]":"138.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"188.9","Cell RNA - hTERT-HME1 [nTPM]":"124.5","Cell RNA - hTERT-RPE1 [nTPM]":"190.8","Cell RNA - HUVEC TERT2 [nTPM]":"220.0","Cell RNA - JURKAT [nTPM]":"74.0","Cell RNA - K-562 [nTPM]":"73.5","Cell RNA - Karpas-707 [nTPM]":"296.3","Cell RNA - LHCN-M2 [nTPM]":"361.9","Cell RNA - MCF7 [nTPM]":"137.9","Cell RNA - MOLT-4 [nTPM]":"116.8","Cell RNA - NB-4 [nTPM]":"108.4","Cell RNA - NTERA-2 [nTPM]":"51.0","Cell RNA - OE19 [nTPM]":"129.2","Cell RNA - PC-3 [nTPM]":"142.7","Cell RNA - REH [nTPM]":"84.9","Cell RNA - RH-30 [nTPM]":"153.8","Cell RNA - RPMI-8226 [nTPM]":"131.3","Cell RNA - RPTEC TERT1 [nTPM]":"202.0","Cell RNA - RT4 [nTPM]":"90.6","Cell RNA - SCLC-21H [nTPM]":"56.1","Cell RNA - SH-SY5Y [nTPM]":"73.2","Cell RNA - SiHa [nTPM]":"118.6","Cell RNA - SK-BR-3 [nTPM]":"113.2","Cell RNA - SK-MEL-30 [nTPM]":"134.0","Cell RNA - SuSa [nTPM]":"92.6","Cell RNA - T-47d [nTPM]":"90.6","Cell RNA - THP-1 [nTPM]":"112.0","Cell RNA - TIME [nTPM]":"340.9","Cell RNA - U-138 MG [nTPM]":"282.0","Cell RNA - U-2 OS [nTPM]":"175.3","Cell RNA - U-2197 [nTPM]":"192.3","Cell RNA - U-251 MG [nTPM]":"137.9","Cell RNA - U-266\/70 [nTPM]":"78.3","Cell RNA - U-266\/84 [nTPM]":"91.2","Cell RNA - U-698 [nTPM]":"72.4","Cell RNA - U-87 MG [nTPM]":"328.8","Cell RNA - U-937 [nTPM]":"67.8","Cell RNA - WM-115 [nTPM]":"237.9","Blood RNA - basophil [nTPM]":"126.3","Blood RNA - classical monocyte [nTPM]":"104.0","Blood RNA - eosinophil [nTPM]":"300.3","Blood RNA - gdT-cell [nTPM]":"75.9","Blood RNA - intermediate monocyte [nTPM]":"135.3","Blood RNA - MAIT T-cell [nTPM]":"76.6","Blood RNA - memory B-cell [nTPM]":"110.1","Blood RNA - memory CD4 T-cell [nTPM]":"72.8","Blood RNA - memory CD8 T-cell [nTPM]":"83.9","Blood RNA - myeloid DC [nTPM]":"154.0","Blood RNA - naive B-cell [nTPM]":"102.7","Blood RNA - naive CD4 T-cell [nTPM]":"50.8","Blood RNA - naive CD8 T-cell [nTPM]":"54.0","Blood RNA - neutrophil [nTPM]":"53.8","Blood RNA - NK-cell [nTPM]":"63.5","Blood RNA - non-classical monocyte [nTPM]":"176.7","Blood RNA - plasmacytoid DC [nTPM]":"140.8","Blood RNA - T-reg [nTPM]":"95.0","Blood RNA - total PBMC [nTPM]":"86.4","Brain RNA - amygdala [nTPM]":"147.1","Brain RNA - basal ganglia [nTPM]":"152.9","Brain RNA - cerebellum [nTPM]":"145.7","Brain RNA - cerebral cortex [nTPM]":"189.9","Brain RNA - hippocampal formation [nTPM]":"138.7","Brain RNA - hypothalamus [nTPM]":"163.9","Brain RNA - medulla oblongata [nTPM]":"194.7","Brain RNA - midbrain [nTPM]":"174.2","Brain RNA - pons [nTPM]":"169.9","Brain RNA - spinal cord [nTPM]":"154.8","Brain RNA - thalamus [nTPM]":"156.7","Brain RNA - white matter [nTPM]":"160.2","Single Cell Type RNA - Adipocytes [nTPM]":"238.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"86.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"62.2","Single Cell Type RNA - Astrocytes [nTPM]":"17.0","Single Cell Type RNA - B-cells [nTPM]":"51.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"110.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"95.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"184.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"27.3","Single Cell Type RNA - Bipolar cells [nTPM]":"16.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"52.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"73.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"106.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"105.8","Single Cell Type RNA - Club cells [nTPM]":"100.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"60.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"110.0","Single Cell Type RNA - dendritic cells [nTPM]":"37.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"90.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"49.0","Single Cell Type RNA - Ductal cells [nTPM]":"216.4","Single Cell Type RNA - Early spermatids [nTPM]":"4.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"51.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"82.9","Single Cell Type RNA - Endothelial cells [nTPM]":"161.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"83.7","Single Cell Type RNA - Erythroid cells [nTPM]":"113.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"107.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"199.3","Single Cell Type RNA - Fibroblasts [nTPM]":"183.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"38.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"65.4","Single Cell Type RNA - granulocytes [nTPM]":"62.8","Single Cell Type RNA - Granulosa cells [nTPM]":"57.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"180.2","Single Cell Type RNA - Hepatocytes [nTPM]":"230.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"108.3","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"16.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"45.8","Single Cell Type RNA - Ionocytes [nTPM]":"142.4","Single Cell Type RNA - Kupffer cells [nTPM]":"50.6","Single Cell Type RNA - Langerhans cells [nTPM]":"112.0","Single Cell Type RNA - Late spermatids [nTPM]":"17.0","Single Cell Type RNA - Leydig cells [nTPM]":"253.9","Single Cell Type RNA - Macrophages [nTPM]":"67.7","Single Cell Type RNA - Melanocytes [nTPM]":"176.1","Single Cell Type RNA - Microglial cells [nTPM]":"25.3","Single Cell Type RNA - monocytes [nTPM]":"112.5","Single Cell Type RNA - Muller glia cells [nTPM]":"91.0","Single Cell Type RNA - NK-cells [nTPM]":"33.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"26.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"156.8","Single Cell Type RNA - Paneth cells [nTPM]":"85.6","Single Cell Type RNA - Peritubular cells [nTPM]":"280.6","Single Cell Type RNA - Plasma cells [nTPM]":"36.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"82.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"116.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"110.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"53.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.4","Single Cell Type RNA - Sertoli cells [nTPM]":"190.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"62.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"202.5","Single Cell Type RNA - Spermatocytes [nTPM]":"23.8","Single Cell Type RNA - Spermatogonia [nTPM]":"45.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"57.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"112.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"117.9","Single Cell Type RNA - T-cells [nTPM]":"43.0","Single Cell Type RNA - Theca cells [nTPM]":"233.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"55.2","Single Cell Type RNA - Urothelial cells [nTPM]":"96.4"},{"Gene":"CYBA","Gene synonym":["p22-PHOX"],"Ensembl":"ENSG00000051523","Gene description":"Cytochrome b-245 alpha chain","Uniprot":["P13498"],"Chromosome":"16","Position":"88643289-88651054","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Electron transport","Transport"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Chronic granulomatous disease","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"742.0","lymphoid tissue":"693.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"1632.1","Hofbauer cells":"2171.9","Kupffer cells":"1734.2","Macrophages":"1682.8","monocytes":"1688.5","NK-cells":"1805.4","Plasma cells":"1990.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"733.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"1058.3","RPMI-8226":"1631.2","THP-1":"1231.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009492"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009492":"AB_2090309"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.19e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.75e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.83e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Tissue RNA - adipose tissue [nTPM]":"149.9","Tissue RNA - adrenal gland [nTPM]":"68.0","Tissue RNA - amygdala [nTPM]":"40.3","Tissue RNA - appendix [nTPM]":"344.4","Tissue RNA - basal ganglia [nTPM]":"41.8","Tissue RNA - bone marrow [nTPM]":"742.0","Tissue RNA - breast [nTPM]":"93.3","Tissue RNA - cerebellum [nTPM]":"46.0","Tissue RNA - cerebral cortex [nTPM]":"58.0","Tissue RNA - cervix [nTPM]":"81.9","Tissue RNA - choroid plexus [nTPM]":"62.4","Tissue RNA - colon [nTPM]":"200.9","Tissue RNA - duodenum [nTPM]":"196.6","Tissue RNA - endometrium 1 [nTPM]":"60.8","Tissue RNA - epididymis [nTPM]":"38.5","Tissue RNA - esophagus [nTPM]":"80.9","Tissue RNA - fallopian tube [nTPM]":"95.4","Tissue RNA - gallbladder [nTPM]":"122.5","Tissue RNA - heart muscle [nTPM]":"93.2","Tissue RNA - hippocampal formation [nTPM]":"38.6","Tissue RNA - hypothalamus [nTPM]":"55.0","Tissue RNA - kidney [nTPM]":"187.7","Tissue RNA - liver [nTPM]":"71.5","Tissue RNA - lung [nTPM]":"234.6","Tissue RNA - lymph node [nTPM]":"333.8","Tissue RNA - medulla oblongata [nTPM]":"73.8","Tissue RNA - midbrain [nTPM]":"49.3","Tissue RNA - ovary [nTPM]":"40.0","Tissue RNA - pancreas [nTPM]":"108.6","Tissue RNA - parathyroid gland [nTPM]":"13.4","Tissue RNA - pituitary gland [nTPM]":"40.6","Tissue RNA - placenta [nTPM]":"54.9","Tissue RNA - pons [nTPM]":"64.1","Tissue RNA - prostate [nTPM]":"75.2","Tissue RNA - rectum [nTPM]":"79.9","Tissue RNA - retina [nTPM]":"1.8","Tissue RNA - salivary gland [nTPM]":"116.7","Tissue RNA - seminal vesicle [nTPM]":"26.6","Tissue RNA - skeletal muscle [nTPM]":"41.8","Tissue RNA - skin 1 [nTPM]":"39.4","Tissue RNA - small intestine [nTPM]":"245.3","Tissue RNA - smooth muscle [nTPM]":"51.3","Tissue RNA - spinal cord [nTPM]":"65.4","Tissue RNA - spleen [nTPM]":"693.1","Tissue RNA - stomach 1 [nTPM]":"236.0","Tissue RNA - testis [nTPM]":"10.4","Tissue RNA - thalamus [nTPM]":"62.4","Tissue RNA - thymus [nTPM]":"87.1","Tissue RNA - thyroid gland [nTPM]":"136.5","Tissue RNA - tongue [nTPM]":"19.9","Tissue RNA - tonsil [nTPM]":"192.8","Tissue RNA - urinary bladder [nTPM]":"144.6","Tissue RNA - vagina [nTPM]":"74.1","Tissue RNA - white matter [nTPM]":"92.2","Cell RNA - A-431 [nTPM]":"2.5","Cell RNA - A549 [nTPM]":"663.0","Cell RNA - AF22 [nTPM]":"2.6","Cell RNA - AN3-CA [nTPM]":"1.5","Cell RNA - ASC diff [nTPM]":"1.3","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"329.5","Cell RNA - BJ [nTPM]":"155.7","Cell RNA - BJ hTERT+ [nTPM]":"77.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"39.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.1","Cell RNA - CACO-2 [nTPM]":"447.2","Cell RNA - CAPAN-2 [nTPM]":"819.6","Cell RNA - Daudi [nTPM]":"510.5","Cell RNA - EFO-21 [nTPM]":"420.7","Cell RNA - fHDF\/TERT166 [nTPM]":"56.4","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"250.5","Cell RNA - HAP1 [nTPM]":"21.4","Cell RNA - HBEC3-KT [nTPM]":"0.9","Cell RNA - HBF TERT88 [nTPM]":"5.8","Cell RNA - HDLM-2 [nTPM]":"146.1","Cell RNA - HEK 293 [nTPM]":"564.1","Cell RNA - HEL [nTPM]":"99.0","Cell RNA - HeLa [nTPM]":"217.7","Cell RNA - Hep G2 [nTPM]":"694.9","Cell RNA - HHSteC [nTPM]":"75.7","Cell RNA - HL-60 [nTPM]":"156.3","Cell RNA - HMC-1 [nTPM]":"397.6","Cell RNA - HSkMC [nTPM]":"80.7","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.6","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"1.9","Cell RNA - HUVEC TERT2 [nTPM]":"23.9","Cell RNA - JURKAT [nTPM]":"103.6","Cell RNA - K-562 [nTPM]":"278.5","Cell RNA - Karpas-707 [nTPM]":"567.5","Cell RNA - LHCN-M2 [nTPM]":"3.2","Cell RNA - MCF7 [nTPM]":"1058.3","Cell RNA - MOLT-4 [nTPM]":"147.9","Cell RNA - NB-4 [nTPM]":"822.3","Cell RNA - NTERA-2 [nTPM]":"106.2","Cell RNA - OE19 [nTPM]":"248.7","Cell RNA - PC-3 [nTPM]":"1.5","Cell RNA - REH [nTPM]":"437.9","Cell RNA - RH-30 [nTPM]":"1.6","Cell RNA - RPMI-8226 [nTPM]":"1631.2","Cell RNA - RPTEC TERT1 [nTPM]":"324.9","Cell RNA - RT4 [nTPM]":"490.9","Cell RNA - SCLC-21H [nTPM]":"84.2","Cell RNA - SH-SY5Y [nTPM]":"76.5","Cell RNA - SiHa [nTPM]":"482.7","Cell RNA - SK-BR-3 [nTPM]":"78.8","Cell RNA - SK-MEL-30 [nTPM]":"138.5","Cell RNA - SuSa [nTPM]":"60.8","Cell RNA - T-47d [nTPM]":"1.4","Cell RNA - THP-1 [nTPM]":"1231.3","Cell RNA - TIME [nTPM]":"129.8","Cell RNA - U-138 MG [nTPM]":"1.5","Cell RNA - U-2 OS [nTPM]":"6.1","Cell RNA - U-2197 [nTPM]":"1.8","Cell RNA - U-251 MG [nTPM]":"2.2","Cell RNA - U-266\/70 [nTPM]":"362.9","Cell RNA - U-266\/84 [nTPM]":"459.9","Cell RNA - U-698 [nTPM]":"543.6","Cell RNA - U-87 MG [nTPM]":"195.5","Cell RNA - U-937 [nTPM]":"464.9","Cell RNA - WM-115 [nTPM]":"53.4","Blood RNA - basophil [nTPM]":"120.2","Blood RNA - classical monocyte [nTPM]":"103.8","Blood RNA - eosinophil [nTPM]":"733.7","Blood RNA - gdT-cell [nTPM]":"76.7","Blood RNA - intermediate monocyte [nTPM]":"150.1","Blood RNA - MAIT T-cell [nTPM]":"55.8","Blood RNA - memory B-cell [nTPM]":"109.8","Blood RNA - memory CD4 T-cell [nTPM]":"36.7","Blood RNA - memory CD8 T-cell [nTPM]":"70.4","Blood RNA - myeloid DC [nTPM]":"107.0","Blood RNA - naive B-cell [nTPM]":"110.7","Blood RNA - naive CD4 T-cell [nTPM]":"28.9","Blood RNA - naive CD8 T-cell [nTPM]":"36.7","Blood RNA - neutrophil [nTPM]":"192.3","Blood RNA - NK-cell [nTPM]":"36.4","Blood RNA - non-classical monocyte [nTPM]":"143.3","Blood RNA - plasmacytoid DC [nTPM]":"196.3","Blood RNA - T-reg [nTPM]":"41.2","Blood RNA - total PBMC [nTPM]":"47.3","Brain RNA - amygdala [nTPM]":"40.3","Brain RNA - basal ganglia [nTPM]":"41.8","Brain RNA - cerebellum [nTPM]":"46.0","Brain RNA - cerebral cortex [nTPM]":"58.0","Brain RNA - hippocampal formation [nTPM]":"38.6","Brain RNA - hypothalamus [nTPM]":"55.0","Brain RNA - medulla oblongata [nTPM]":"73.8","Brain RNA - midbrain [nTPM]":"49.3","Brain RNA - pons [nTPM]":"64.1","Brain RNA - spinal cord [nTPM]":"65.4","Brain RNA - thalamus [nTPM]":"62.4","Brain RNA - white matter [nTPM]":"92.2","Single Cell Type RNA - Adipocytes [nTPM]":"157.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.4","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1290.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"119.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"233.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"420.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"53.5","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"131.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"133.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"368.9","Single Cell Type RNA - Club cells [nTPM]":"487.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"285.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"45.3","Single Cell Type RNA - dendritic cells [nTPM]":"1632.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"807.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"127.2","Single Cell Type RNA - Ductal cells [nTPM]":"636.8","Single Cell Type RNA - Early spermatids [nTPM]":"4.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"219.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"137.5","Single Cell Type RNA - Endothelial cells [nTPM]":"137.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"230.5","Single Cell Type RNA - Erythroid cells [nTPM]":"162.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"155.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"299.0","Single Cell Type RNA - Fibroblasts [nTPM]":"184.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"285.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"312.5","Single Cell Type RNA - granulocytes [nTPM]":"279.0","Single Cell Type RNA - Granulosa cells [nTPM]":"104.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"317.0","Single Cell Type RNA - Hepatocytes [nTPM]":"23.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"2171.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"540.3","Single Cell Type RNA - Ionocytes [nTPM]":"233.9","Single Cell Type RNA - Kupffer cells [nTPM]":"1734.2","Single Cell Type RNA - Langerhans cells [nTPM]":"1370.8","Single Cell Type RNA - Late spermatids [nTPM]":"14.0","Single Cell Type RNA - Leydig cells [nTPM]":"50.1","Single Cell Type RNA - Macrophages [nTPM]":"1682.8","Single Cell Type RNA - Melanocytes [nTPM]":"1152.6","Single Cell Type RNA - Microglial cells [nTPM]":"32.8","Single Cell Type RNA - monocytes [nTPM]":"1688.5","Single Cell Type RNA - Muller glia cells [nTPM]":"1.6","Single Cell Type RNA - NK-cells [nTPM]":"1805.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"682.8","Single Cell Type RNA - Paneth cells [nTPM]":"1045.8","Single Cell Type RNA - Peritubular cells [nTPM]":"21.4","Single Cell Type RNA - Plasma cells [nTPM]":"1990.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"191.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"390.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1057.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"529.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.7","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"44.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"164.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.9","Single Cell Type RNA - Spermatogonia [nTPM]":"15.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"75.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"85.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"118.2","Single Cell Type RNA - T-cells [nTPM]":"838.6","Single Cell Type RNA - Theca cells [nTPM]":"20.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"805.2","Single Cell Type RNA - Urothelial cells [nTPM]":"436.9"},{"Gene":"CYBB","Gene synonym":["CGD","GP91-PHOX","NOX2"],"Ensembl":"ENSG00000165168","Gene description":"Cytochrome b-245 beta chain","Uniprot":["P04839"],"Chromosome":"X","Position":"37780059-37813461","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Electron transport","Ion transport","Transport"],"Molecular function":["Ion channel","Oxidoreductase","Voltage-gated channel"],"Disease involvement":["Chronic granulomatous disease","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"160.9","lymphoid tissue":"158.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"157.2","Kupffer cells":"456.0","Macrophages":"469.3","monocytes":"396.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"276.3","intermediate monocyte":"261.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"90.9","granulocytes":"110.5","monocytes":"276.3"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Daudi":"52.8","NB-4":"64.2","REH":"54.6","RPMI-8226":"210.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051227"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051227":"AB_2681395"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-2"},"Tissue RNA - adipose tissue [nTPM]":"40.5","Tissue RNA - adrenal gland [nTPM]":"28.4","Tissue RNA - amygdala [nTPM]":"5.5","Tissue RNA - appendix [nTPM]":"158.9","Tissue RNA - basal ganglia [nTPM]":"5.3","Tissue RNA - bone marrow [nTPM]":"160.9","Tissue RNA - breast [nTPM]":"15.2","Tissue RNA - cerebellum [nTPM]":"6.5","Tissue RNA - cerebral cortex [nTPM]":"5.5","Tissue RNA - cervix [nTPM]":"12.3","Tissue RNA - choroid plexus [nTPM]":"12.4","Tissue RNA - colon [nTPM]":"22.3","Tissue RNA - duodenum [nTPM]":"19.3","Tissue RNA - endometrium 1 [nTPM]":"9.3","Tissue RNA - epididymis [nTPM]":"4.3","Tissue RNA - esophagus [nTPM]":"8.9","Tissue RNA - fallopian tube [nTPM]":"9.9","Tissue RNA - gallbladder [nTPM]":"26.2","Tissue RNA - heart muscle [nTPM]":"8.0","Tissue RNA - hippocampal formation [nTPM]":"4.7","Tissue RNA - hypothalamus [nTPM]":"9.1","Tissue RNA - kidney [nTPM]":"8.0","Tissue RNA - liver [nTPM]":"27.5","Tissue RNA - lung [nTPM]":"91.5","Tissue RNA - lymph node [nTPM]":"97.1","Tissue RNA - medulla oblongata [nTPM]":"15.1","Tissue RNA - midbrain [nTPM]":"9.6","Tissue RNA - ovary [nTPM]":"6.9","Tissue RNA - pancreas [nTPM]":"4.0","Tissue RNA - parathyroid gland [nTPM]":"4.4","Tissue RNA - pituitary gland [nTPM]":"2.5","Tissue RNA - placenta [nTPM]":"54.6","Tissue RNA - pons [nTPM]":"13.3","Tissue RNA - prostate [nTPM]":"6.7","Tissue RNA - rectum [nTPM]":"30.6","Tissue RNA - retina [nTPM]":"1.7","Tissue RNA - salivary gland [nTPM]":"7.0","Tissue RNA - seminal vesicle [nTPM]":"9.7","Tissue RNA - skeletal muscle [nTPM]":"3.7","Tissue RNA - skin 1 [nTPM]":"2.2","Tissue RNA - small intestine [nTPM]":"22.3","Tissue RNA - smooth muscle [nTPM]":"55.5","Tissue RNA - spinal cord [nTPM]":"12.5","Tissue RNA - spleen [nTPM]":"89.0","Tissue RNA - stomach 1 [nTPM]":"17.2","Tissue RNA - testis [nTPM]":"4.7","Tissue RNA - thalamus [nTPM]":"11.1","Tissue RNA - thymus [nTPM]":"18.3","Tissue RNA - thyroid gland [nTPM]":"5.3","Tissue RNA - tongue [nTPM]":"5.5","Tissue RNA - tonsil [nTPM]":"73.2","Tissue RNA - urinary bladder [nTPM]":"46.8","Tissue RNA - vagina [nTPM]":"2.3","Tissue RNA - white matter [nTPM]":"24.0","Cell RNA - A-431 [nTPM]":"1.1","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"1.2","Cell RNA - Daudi [nTPM]":"52.8","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"1.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"3.6","Cell RNA - HeLa [nTPM]":"0.6","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"3.6","Cell RNA - HMC-1 [nTPM]":"0.8","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"1.6","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"64.2","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"54.6","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"210.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"20.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.6","Cell RNA - U-266\/84 [nTPM]":"1.6","Cell RNA - U-698 [nTPM]":"3.4","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"8.9","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"2.2","Blood RNA - classical monocyte [nTPM]":"276.3","Blood RNA - eosinophil [nTPM]":"110.5","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"261.6","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"39.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"62.8","Blood RNA - naive B-cell [nTPM]":"32.8","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"19.2","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"237.1","Blood RNA - plasmacytoid DC [nTPM]":"90.9","Blood RNA - T-reg [nTPM]":"0.9","Blood RNA - total PBMC [nTPM]":"162.5","Brain RNA - amygdala [nTPM]":"5.5","Brain RNA - basal ganglia [nTPM]":"5.3","Brain RNA - cerebellum [nTPM]":"6.5","Brain RNA - cerebral cortex [nTPM]":"5.5","Brain RNA - hippocampal formation [nTPM]":"4.7","Brain RNA - hypothalamus [nTPM]":"9.1","Brain RNA - medulla oblongata [nTPM]":"15.1","Brain RNA - midbrain [nTPM]":"9.6","Brain RNA - pons [nTPM]":"13.3","Brain RNA - spinal cord [nTPM]":"12.5","Brain RNA - thalamus [nTPM]":"11.1","Brain RNA - white matter [nTPM]":"24.0","Single Cell Type RNA - Adipocytes [nTPM]":"2.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.4","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"99.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"13.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.9","Single Cell Type RNA - dendritic cells [nTPM]":"82.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"8.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.1","Single Cell Type RNA - Fibroblasts [nTPM]":"4.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"3.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"157.2","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"456.0","Single Cell Type RNA - Langerhans cells [nTPM]":"25.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"469.3","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"76.8","Single Cell Type RNA - monocytes [nTPM]":"396.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"13.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.8","Single Cell Type RNA - T-cells [nTPM]":"7.5","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"CYC1","Gene synonym":["UQCR4"],"Ensembl":"ENSG00000179091","Gene description":"Cytochrome c1","Uniprot":["P08574"],"Chromosome":"8","Position":"144095039-144097525","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"730.0","tongue":"724.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"817.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"PC-3":"1125.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001247"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"45000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA001247":"AB_1078602"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.89e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-2"},"Tissue RNA - adipose tissue [nTPM]":"84.7","Tissue RNA - adrenal gland [nTPM]":"173.2","Tissue RNA - amygdala [nTPM]":"92.1","Tissue RNA - appendix [nTPM]":"62.4","Tissue RNA - basal ganglia [nTPM]":"97.2","Tissue RNA - bone marrow [nTPM]":"104.4","Tissue RNA - breast [nTPM]":"72.7","Tissue RNA - cerebellum [nTPM]":"115.4","Tissue RNA - cerebral cortex [nTPM]":"103.8","Tissue RNA - cervix [nTPM]":"71.4","Tissue RNA - choroid plexus [nTPM]":"102.4","Tissue RNA - colon [nTPM]":"162.6","Tissue RNA - duodenum [nTPM]":"171.2","Tissue RNA - endometrium 1 [nTPM]":"75.9","Tissue RNA - epididymis [nTPM]":"35.7","Tissue RNA - esophagus [nTPM]":"155.5","Tissue RNA - fallopian tube [nTPM]":"67.8","Tissue RNA - gallbladder [nTPM]":"39.5","Tissue RNA - heart muscle [nTPM]":"527.7","Tissue RNA - hippocampal formation [nTPM]":"92.3","Tissue RNA - hypothalamus [nTPM]":"105.3","Tissue RNA - kidney [nTPM]":"152.6","Tissue RNA - liver [nTPM]":"180.4","Tissue RNA - lung [nTPM]":"56.7","Tissue RNA - lymph node [nTPM]":"55.8","Tissue RNA - medulla oblongata [nTPM]":"99.8","Tissue RNA - midbrain [nTPM]":"96.9","Tissue RNA - ovary [nTPM]":"63.6","Tissue RNA - pancreas [nTPM]":"101.2","Tissue RNA - parathyroid gland [nTPM]":"163.3","Tissue RNA - pituitary gland [nTPM]":"58.2","Tissue RNA - placenta [nTPM]":"45.8","Tissue RNA - pons [nTPM]":"103.1","Tissue RNA - prostate [nTPM]":"67.8","Tissue RNA - rectum [nTPM]":"111.0","Tissue RNA - retina [nTPM]":"42.0","Tissue RNA - salivary gland [nTPM]":"104.4","Tissue RNA - seminal vesicle [nTPM]":"70.0","Tissue RNA - skeletal muscle [nTPM]":"730.0","Tissue RNA - skin 1 [nTPM]":"106.5","Tissue RNA - small intestine [nTPM]":"127.5","Tissue RNA - smooth muscle [nTPM]":"59.9","Tissue RNA - spinal cord [nTPM]":"94.9","Tissue RNA - spleen [nTPM]":"70.1","Tissue RNA - stomach 1 [nTPM]":"139.6","Tissue RNA - testis [nTPM]":"38.9","Tissue RNA - thalamus [nTPM]":"106.9","Tissue RNA - thymus [nTPM]":"63.4","Tissue RNA - thyroid gland [nTPM]":"64.8","Tissue RNA - tongue [nTPM]":"724.9","Tissue RNA - tonsil [nTPM]":"61.0","Tissue RNA - urinary bladder [nTPM]":"92.0","Tissue RNA - vagina [nTPM]":"86.5","Tissue RNA - white matter [nTPM]":"99.6","Cell RNA - A-431 [nTPM]":"172.0","Cell RNA - A549 [nTPM]":"381.4","Cell RNA - AF22 [nTPM]":"98.9","Cell RNA - AN3-CA [nTPM]":"208.4","Cell RNA - ASC diff [nTPM]":"80.5","Cell RNA - ASC TERT1 [nTPM]":"88.5","Cell RNA - BEWO [nTPM]":"189.6","Cell RNA - BJ [nTPM]":"96.7","Cell RNA - BJ hTERT+ [nTPM]":"116.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"240.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"156.9","Cell RNA - CACO-2 [nTPM]":"269.4","Cell RNA - CAPAN-2 [nTPM]":"208.2","Cell RNA - Daudi [nTPM]":"241.0","Cell RNA - EFO-21 [nTPM]":"210.8","Cell RNA - fHDF\/TERT166 [nTPM]":"129.8","Cell RNA - GAMG [nTPM]":"116.2","Cell RNA - HaCaT [nTPM]":"247.3","Cell RNA - HAP1 [nTPM]":"217.9","Cell RNA - HBEC3-KT [nTPM]":"191.2","Cell RNA - HBF TERT88 [nTPM]":"89.8","Cell RNA - HDLM-2 [nTPM]":"148.2","Cell RNA - HEK 293 [nTPM]":"289.2","Cell RNA - HEL [nTPM]":"259.7","Cell RNA - HeLa [nTPM]":"306.5","Cell RNA - Hep G2 [nTPM]":"250.4","Cell RNA - HHSteC [nTPM]":"143.1","Cell RNA - HL-60 [nTPM]":"154.7","Cell RNA - HMC-1 [nTPM]":"162.5","Cell RNA - HSkMC [nTPM]":"129.4","Cell RNA - hTCEpi [nTPM]":"234.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"153.2","Cell RNA - hTERT-HME1 [nTPM]":"301.4","Cell RNA - hTERT-RPE1 [nTPM]":"80.6","Cell RNA - HUVEC TERT2 [nTPM]":"141.3","Cell RNA - JURKAT [nTPM]":"163.7","Cell RNA - K-562 [nTPM]":"240.4","Cell RNA - Karpas-707 [nTPM]":"208.2","Cell RNA - LHCN-M2 [nTPM]":"127.7","Cell RNA - MCF7 [nTPM]":"616.8","Cell RNA - MOLT-4 [nTPM]":"292.0","Cell RNA - NB-4 [nTPM]":"143.5","Cell RNA - NTERA-2 [nTPM]":"115.1","Cell RNA - OE19 [nTPM]":"476.8","Cell RNA - PC-3 [nTPM]":"1125.5","Cell RNA - REH [nTPM]":"253.7","Cell RNA - RH-30 [nTPM]":"132.4","Cell RNA - RPMI-8226 [nTPM]":"422.1","Cell RNA - RPTEC TERT1 [nTPM]":"199.7","Cell RNA - RT4 [nTPM]":"273.0","Cell RNA - SCLC-21H [nTPM]":"263.3","Cell RNA - SH-SY5Y [nTPM]":"117.2","Cell RNA - SiHa [nTPM]":"267.8","Cell RNA - SK-BR-3 [nTPM]":"365.7","Cell RNA - SK-MEL-30 [nTPM]":"200.0","Cell RNA - SuSa [nTPM]":"54.0","Cell RNA - T-47d [nTPM]":"302.5","Cell RNA - THP-1 [nTPM]":"233.2","Cell RNA - TIME [nTPM]":"108.8","Cell RNA - U-138 MG [nTPM]":"152.1","Cell RNA - U-2 OS [nTPM]":"321.6","Cell RNA - U-2197 [nTPM]":"169.6","Cell RNA - U-251 MG [nTPM]":"299.7","Cell RNA - U-266\/70 [nTPM]":"229.1","Cell RNA - U-266\/84 [nTPM]":"179.7","Cell RNA - U-698 [nTPM]":"183.8","Cell RNA - U-87 MG [nTPM]":"193.2","Cell RNA - U-937 [nTPM]":"261.9","Cell RNA - WM-115 [nTPM]":"198.4","Blood RNA - basophil [nTPM]":"185.7","Blood RNA - classical monocyte [nTPM]":"340.4","Blood RNA - eosinophil [nTPM]":"95.7","Blood RNA - gdT-cell [nTPM]":"131.6","Blood RNA - intermediate monocyte [nTPM]":"360.4","Blood RNA - MAIT T-cell [nTPM]":"139.8","Blood RNA - memory B-cell [nTPM]":"208.7","Blood RNA - memory CD4 T-cell [nTPM]":"108.1","Blood RNA - memory CD8 T-cell [nTPM]":"141.5","Blood RNA - myeloid DC [nTPM]":"444.1","Blood RNA - naive B-cell [nTPM]":"180.3","Blood RNA - naive CD4 T-cell [nTPM]":"104.9","Blood RNA - naive CD8 T-cell [nTPM]":"134.6","Blood RNA - neutrophil [nTPM]":"32.7","Blood RNA - NK-cell [nTPM]":"187.8","Blood RNA - non-classical monocyte [nTPM]":"278.8","Blood RNA - plasmacytoid DC [nTPM]":"251.0","Blood RNA - T-reg [nTPM]":"158.2","Blood RNA - total PBMC [nTPM]":"397.1","Brain RNA - amygdala [nTPM]":"92.1","Brain RNA - basal ganglia [nTPM]":"97.2","Brain RNA - cerebellum [nTPM]":"115.4","Brain RNA - cerebral cortex [nTPM]":"103.8","Brain RNA - hippocampal formation [nTPM]":"92.3","Brain RNA - hypothalamus [nTPM]":"105.3","Brain RNA - medulla oblongata [nTPM]":"99.8","Brain RNA - midbrain [nTPM]":"96.9","Brain RNA - pons [nTPM]":"103.1","Brain RNA - spinal cord [nTPM]":"94.9","Brain RNA - thalamus [nTPM]":"106.9","Brain RNA - white matter [nTPM]":"99.6","Single Cell Type RNA - Adipocytes [nTPM]":"77.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.3","Single Cell Type RNA - Astrocytes [nTPM]":"23.5","Single Cell Type RNA - B-cells [nTPM]":"94.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"156.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"191.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"394.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"62.6","Single Cell Type RNA - Bipolar cells [nTPM]":"113.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"110.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"102.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"402.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"181.6","Single Cell Type RNA - Club cells [nTPM]":"156.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"79.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"81.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"263.6","Single Cell Type RNA - dendritic cells [nTPM]":"61.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"516.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"817.8","Single Cell Type RNA - Ductal cells [nTPM]":"239.9","Single Cell Type RNA - Early spermatids [nTPM]":"81.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"59.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"68.1","Single Cell Type RNA - Endothelial cells [nTPM]":"88.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"146.4","Single Cell Type RNA - Erythroid cells [nTPM]":"130.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"289.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"257.1","Single Cell Type RNA - Fibroblasts [nTPM]":"102.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"144.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"60.2","Single Cell Type RNA - granulocytes [nTPM]":"59.7","Single Cell Type RNA - Granulosa cells [nTPM]":"89.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"62.4","Single Cell Type RNA - Hepatocytes [nTPM]":"239.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"246.3","Single Cell Type RNA - Horizontal cells [nTPM]":"87.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"390.4","Single Cell Type RNA - Ionocytes [nTPM]":"272.6","Single Cell Type RNA - Kupffer cells [nTPM]":"104.8","Single Cell Type RNA - Langerhans cells [nTPM]":"139.4","Single Cell Type RNA - Late spermatids [nTPM]":"88.6","Single Cell Type RNA - Leydig cells [nTPM]":"88.9","Single Cell Type RNA - Macrophages [nTPM]":"101.4","Single Cell Type RNA - Melanocytes [nTPM]":"179.7","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"208.4","Single Cell Type RNA - Muller glia cells [nTPM]":"115.2","Single Cell Type RNA - NK-cells [nTPM]":"92.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"290.6","Single Cell Type RNA - Paneth cells [nTPM]":"332.5","Single Cell Type RNA - Peritubular cells [nTPM]":"90.7","Single Cell Type RNA - Plasma cells [nTPM]":"149.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"237.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"570.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"468.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"86.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"100.9","Single Cell Type RNA - Sertoli cells [nTPM]":"72.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"109.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"250.6","Single Cell Type RNA - Spermatocytes [nTPM]":"83.1","Single Cell Type RNA - Spermatogonia [nTPM]":"116.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"212.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"163.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"236.8","Single Cell Type RNA - T-cells [nTPM]":"63.8","Single Cell Type RNA - Theca cells [nTPM]":"197.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"602.6","Single Cell Type RNA - Urothelial cells [nTPM]":"258.3"},{"Gene":"CYLD","Gene synonym":["CYLD1","KIAA0849","USPL2"],"Ensembl":"ENSG00000083799","Gene description":"CYLD lysine 63 deubiquitinase","Uniprot":["Q9NQC7"],"Chromosome":"16","Position":"50742050-50801935","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","Immunity","Innate immunity","Ubl conjugation pathway","Wnt signaling pathway"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"94.3"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"136.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011713","HPA050095"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Centriolar satellite"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Centriolar satellite"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB011713":"AB_731794","HPA050095":"AB_2681013"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-2"},"Tissue RNA - adipose tissue [nTPM]":"14.3","Tissue RNA - adrenal gland [nTPM]":"22.0","Tissue RNA - amygdala [nTPM]":"23.9","Tissue RNA - appendix [nTPM]":"38.8","Tissue RNA - basal ganglia [nTPM]":"23.5","Tissue RNA - bone marrow [nTPM]":"94.3","Tissue RNA - breast [nTPM]":"13.6","Tissue RNA - cerebellum [nTPM]":"17.9","Tissue RNA - cerebral cortex [nTPM]":"18.2","Tissue RNA - cervix [nTPM]":"13.0","Tissue RNA - choroid plexus [nTPM]":"22.3","Tissue RNA - colon [nTPM]":"16.3","Tissue RNA - duodenum [nTPM]":"16.1","Tissue RNA - endometrium 1 [nTPM]":"15.1","Tissue RNA - epididymis [nTPM]":"12.1","Tissue RNA - esophagus [nTPM]":"23.3","Tissue RNA - fallopian tube [nTPM]":"11.0","Tissue RNA - gallbladder [nTPM]":"20.5","Tissue RNA - heart muscle [nTPM]":"20.1","Tissue RNA - hippocampal formation [nTPM]":"17.3","Tissue RNA - hypothalamus [nTPM]":"23.3","Tissue RNA - kidney [nTPM]":"14.2","Tissue RNA - liver [nTPM]":"21.0","Tissue RNA - lung [nTPM]":"21.5","Tissue RNA - lymph node [nTPM]":"53.4","Tissue RNA - medulla oblongata [nTPM]":"21.3","Tissue RNA - midbrain [nTPM]":"27.8","Tissue RNA - ovary [nTPM]":"15.4","Tissue RNA - pancreas [nTPM]":"15.2","Tissue RNA - parathyroid gland [nTPM]":"23.0","Tissue RNA - pituitary gland [nTPM]":"15.4","Tissue RNA - placenta [nTPM]":"15.4","Tissue RNA - pons [nTPM]":"23.6","Tissue RNA - prostate [nTPM]":"16.3","Tissue RNA - rectum [nTPM]":"19.3","Tissue RNA - retina [nTPM]":"22.0","Tissue RNA - salivary gland [nTPM]":"18.9","Tissue RNA - seminal vesicle [nTPM]":"16.0","Tissue RNA - skeletal muscle [nTPM]":"34.3","Tissue RNA - skin 1 [nTPM]":"15.2","Tissue RNA - small intestine [nTPM]":"16.2","Tissue RNA - smooth muscle [nTPM]":"16.8","Tissue RNA - spinal cord [nTPM]":"21.6","Tissue RNA - spleen [nTPM]":"39.0","Tissue RNA - stomach 1 [nTPM]":"19.9","Tissue RNA - testis [nTPM]":"38.3","Tissue RNA - thalamus [nTPM]":"32.7","Tissue RNA - thymus [nTPM]":"35.6","Tissue RNA - thyroid gland [nTPM]":"24.9","Tissue RNA - tongue [nTPM]":"20.5","Tissue RNA - tonsil [nTPM]":"48.4","Tissue RNA - urinary bladder [nTPM]":"24.1","Tissue RNA - vagina [nTPM]":"12.9","Tissue RNA - white matter [nTPM]":"24.2","Cell RNA - A-431 [nTPM]":"26.9","Cell RNA - A549 [nTPM]":"8.3","Cell RNA - AF22 [nTPM]":"9.4","Cell RNA - AN3-CA [nTPM]":"10.6","Cell RNA - ASC diff [nTPM]":"14.3","Cell RNA - ASC TERT1 [nTPM]":"21.0","Cell RNA - BEWO [nTPM]":"8.7","Cell RNA - BJ [nTPM]":"39.1","Cell RNA - BJ hTERT+ [nTPM]":"56.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"39.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.4","Cell RNA - CACO-2 [nTPM]":"6.9","Cell RNA - CAPAN-2 [nTPM]":"12.5","Cell RNA - Daudi [nTPM]":"30.7","Cell RNA - EFO-21 [nTPM]":"13.7","Cell RNA - fHDF\/TERT166 [nTPM]":"38.3","Cell RNA - GAMG [nTPM]":"43.4","Cell RNA - HaCaT [nTPM]":"10.3","Cell RNA - HAP1 [nTPM]":"11.3","Cell RNA - HBEC3-KT [nTPM]":"23.7","Cell RNA - HBF TERT88 [nTPM]":"58.7","Cell RNA - HDLM-2 [nTPM]":"136.6","Cell RNA - HEK 293 [nTPM]":"16.6","Cell RNA - HEL [nTPM]":"15.5","Cell RNA - HeLa [nTPM]":"15.3","Cell RNA - Hep G2 [nTPM]":"5.8","Cell RNA - HHSteC [nTPM]":"29.1","Cell RNA - HL-60 [nTPM]":"15.4","Cell RNA - HMC-1 [nTPM]":"69.5","Cell RNA - HSkMC [nTPM]":"23.0","Cell RNA - hTCEpi [nTPM]":"18.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"48.1","Cell RNA - hTERT-HME1 [nTPM]":"50.1","Cell RNA - hTERT-RPE1 [nTPM]":"37.7","Cell RNA - HUVEC TERT2 [nTPM]":"16.3","Cell RNA - JURKAT [nTPM]":"21.3","Cell RNA - K-562 [nTPM]":"6.6","Cell RNA - Karpas-707 [nTPM]":"26.1","Cell RNA - LHCN-M2 [nTPM]":"56.4","Cell RNA - MCF7 [nTPM]":"4.0","Cell RNA - MOLT-4 [nTPM]":"14.4","Cell RNA - NB-4 [nTPM]":"22.3","Cell RNA - NTERA-2 [nTPM]":"10.1","Cell RNA - OE19 [nTPM]":"8.5","Cell RNA - PC-3 [nTPM]":"13.3","Cell RNA - REH [nTPM]":"13.4","Cell RNA - RH-30 [nTPM]":"18.8","Cell RNA - RPMI-8226 [nTPM]":"29.4","Cell RNA - RPTEC TERT1 [nTPM]":"12.9","Cell RNA - RT4 [nTPM]":"9.1","Cell RNA - SCLC-21H [nTPM]":"12.0","Cell RNA - SH-SY5Y [nTPM]":"9.2","Cell RNA - SiHa [nTPM]":"33.1","Cell RNA - SK-BR-3 [nTPM]":"11.2","Cell RNA - SK-MEL-30 [nTPM]":"9.8","Cell RNA - SuSa [nTPM]":"14.3","Cell RNA - T-47d [nTPM]":"11.0","Cell RNA - THP-1 [nTPM]":"18.9","Cell RNA - TIME [nTPM]":"18.6","Cell RNA - U-138 MG [nTPM]":"67.2","Cell RNA - U-2 OS [nTPM]":"15.4","Cell RNA - U-2197 [nTPM]":"23.4","Cell RNA - U-251 MG [nTPM]":"15.9","Cell RNA - U-266\/70 [nTPM]":"68.0","Cell RNA - U-266\/84 [nTPM]":"68.4","Cell RNA - U-698 [nTPM]":"33.2","Cell RNA - U-87 MG [nTPM]":"49.3","Cell RNA - U-937 [nTPM]":"16.7","Cell RNA - WM-115 [nTPM]":"14.7","Blood RNA - basophil [nTPM]":"64.6","Blood RNA - classical monocyte [nTPM]":"15.2","Blood RNA - eosinophil [nTPM]":"38.3","Blood RNA - gdT-cell [nTPM]":"18.1","Blood RNA - intermediate monocyte [nTPM]":"17.7","Blood RNA - MAIT T-cell [nTPM]":"21.8","Blood RNA - memory B-cell [nTPM]":"17.2","Blood RNA - memory CD4 T-cell [nTPM]":"27.1","Blood RNA - memory CD8 T-cell [nTPM]":"24.5","Blood RNA - myeloid DC [nTPM]":"18.3","Blood RNA - naive B-cell [nTPM]":"11.1","Blood RNA - naive CD4 T-cell [nTPM]":"24.4","Blood RNA - naive CD8 T-cell [nTPM]":"19.4","Blood RNA - neutrophil [nTPM]":"32.3","Blood RNA - NK-cell [nTPM]":"25.7","Blood RNA - non-classical monocyte [nTPM]":"18.8","Blood RNA - plasmacytoid DC [nTPM]":"11.0","Blood RNA - T-reg [nTPM]":"37.3","Blood RNA - total PBMC [nTPM]":"19.5","Brain RNA - amygdala [nTPM]":"23.9","Brain RNA - basal ganglia [nTPM]":"23.5","Brain RNA - cerebellum [nTPM]":"17.9","Brain RNA - cerebral cortex [nTPM]":"18.2","Brain RNA - hippocampal formation [nTPM]":"17.3","Brain RNA - hypothalamus [nTPM]":"23.3","Brain RNA - medulla oblongata [nTPM]":"21.3","Brain RNA - midbrain [nTPM]":"27.8","Brain RNA - pons [nTPM]":"23.6","Brain RNA - spinal cord [nTPM]":"21.6","Brain RNA - thalamus [nTPM]":"32.7","Brain RNA - white matter [nTPM]":"24.2","Single Cell Type RNA - Adipocytes [nTPM]":"28.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.8","Single Cell Type RNA - Astrocytes [nTPM]":"31.6","Single Cell Type RNA - B-cells [nTPM]":"87.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"120.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"59.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"32.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"40.9","Single Cell Type RNA - Bipolar cells [nTPM]":"89.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"35.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"26.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"34.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"32.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"93.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.8","Single Cell Type RNA - dendritic cells [nTPM]":"84.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"28.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"20.0","Single Cell Type RNA - Early spermatids [nTPM]":"48.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"24.9","Single Cell Type RNA - Endothelial cells [nTPM]":"36.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"31.1","Single Cell Type RNA - Erythroid cells [nTPM]":"26.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"51.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.4","Single Cell Type RNA - Fibroblasts [nTPM]":"37.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"22.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"47.1","Single Cell Type RNA - granulocytes [nTPM]":"80.5","Single Cell Type RNA - Granulosa cells [nTPM]":"21.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"27.8","Single Cell Type RNA - Hepatocytes [nTPM]":"25.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"21.5","Single Cell Type RNA - Horizontal cells [nTPM]":"67.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"54.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.7","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"40.0","Single Cell Type RNA - Langerhans cells [nTPM]":"127.6","Single Cell Type RNA - Late spermatids [nTPM]":"31.3","Single Cell Type RNA - Leydig cells [nTPM]":"25.4","Single Cell Type RNA - Macrophages [nTPM]":"66.4","Single Cell Type RNA - Melanocytes [nTPM]":"74.7","Single Cell Type RNA - Microglial cells [nTPM]":"57.1","Single Cell Type RNA - monocytes [nTPM]":"63.7","Single Cell Type RNA - Muller glia cells [nTPM]":"23.3","Single Cell Type RNA - NK-cells [nTPM]":"70.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"51.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"119.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.0","Single Cell Type RNA - Paneth cells [nTPM]":"22.4","Single Cell Type RNA - Peritubular cells [nTPM]":"21.1","Single Cell Type RNA - Plasma cells [nTPM]":"79.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"66.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"48.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"54.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"30.5","Single Cell Type RNA - Spermatocytes [nTPM]":"59.2","Single Cell Type RNA - Spermatogonia [nTPM]":"15.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"64.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"155.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.1","Single Cell Type RNA - T-cells [nTPM]":"119.5","Single Cell Type RNA - Theca cells [nTPM]":"21.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.8","Single Cell Type RNA - Urothelial cells [nTPM]":"66.7"},{"Gene":"CYP11B2","Gene synonym":["ALDOS","CPN2","CYP11B","CYP11BL","P-450C18","P450aldo"],"Ensembl":"ENSG00000179142","Gene description":"Cytochrome P450 family 11 subfamily B member 2","Uniprot":["P19099"],"Chromosome":"8","Position":"142910559-142917843","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid metabolism","Steroid metabolism","Steroidogenesis"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"603","RNA tissue specific nTPM":{"adrenal gland":"179.0"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049171","HPA049565","HPA056348","HPA057752"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 43: Cardiomyocytes - Nuclear processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA049171":"AB_2680661","HPA049565":null,"HPA056348":"AB_2683104","HPA057752":"AB_2683516"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"179.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CYP1B1","Gene synonym":["CP1B","GLC3A"],"Ensembl":"ENSG00000138061","Gene description":"Cytochrome P450 family 1 subfamily B member 1","Uniprot":["Q16678"],"Chromosome":"2","Position":"38066973-38109902","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism","Steroid metabolism"],"Molecular function":["Lyase","Monooxygenase","Oxidoreductase"],"Disease involvement":["Disease variant","Glaucoma","Peters anomaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Peritubular cells":"170.8","Prostatic glandular cells":"747.6","Urothelial cells":"498.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"classical monocyte":"156.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"24","RNA blood lineage specific nTPM":{"monocytes":"156.9"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"128.7","ASC TERT1":"136.8","HSkMC":"551.3","hTERT-RPE1":"128.9","SiHa":"270.0","U-87 MG":"142.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"34.6"},"Antibody":["CAB011705","HPA026863"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB011705":"AB_731810","HPA026863":"AB_10600900"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.39e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.76e-4"},"Tissue RNA - adipose tissue [nTPM]":"28.4","Tissue RNA - adrenal gland [nTPM]":"12.0","Tissue RNA - amygdala [nTPM]":"2.7","Tissue RNA - appendix [nTPM]":"31.9","Tissue RNA - basal ganglia [nTPM]":"6.2","Tissue RNA - bone marrow [nTPM]":"2.0","Tissue RNA - breast [nTPM]":"29.4","Tissue RNA - cerebellum [nTPM]":"1.6","Tissue RNA - cerebral cortex [nTPM]":"8.9","Tissue RNA - cervix [nTPM]":"34.9","Tissue RNA - choroid plexus [nTPM]":"10.4","Tissue RNA - colon [nTPM]":"3.7","Tissue RNA - duodenum [nTPM]":"2.2","Tissue RNA - endometrium 1 [nTPM]":"41.0","Tissue RNA - epididymis [nTPM]":"19.5","Tissue RNA - esophagus [nTPM]":"7.6","Tissue RNA - fallopian tube [nTPM]":"44.9","Tissue RNA - gallbladder [nTPM]":"23.8","Tissue RNA - heart muscle [nTPM]":"29.2","Tissue RNA - hippocampal formation [nTPM]":"2.5","Tissue RNA - hypothalamus [nTPM]":"2.3","Tissue RNA - kidney [nTPM]":"24.1","Tissue RNA - liver [nTPM]":"7.0","Tissue RNA - lung [nTPM]":"16.8","Tissue RNA - lymph node [nTPM]":"11.6","Tissue RNA - medulla oblongata [nTPM]":"3.6","Tissue RNA - midbrain [nTPM]":"2.9","Tissue RNA - ovary [nTPM]":"5.6","Tissue RNA - pancreas [nTPM]":"7.2","Tissue RNA - parathyroid gland [nTPM]":"0.9","Tissue RNA - pituitary gland [nTPM]":"14.8","Tissue RNA - placenta [nTPM]":"4.5","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"34.7","Tissue RNA - rectum [nTPM]":"2.1","Tissue RNA - retina [nTPM]":"1.2","Tissue RNA - salivary gland [nTPM]":"4.3","Tissue RNA - seminal vesicle [nTPM]":"39.2","Tissue RNA - skeletal muscle [nTPM]":"3.4","Tissue RNA - skin 1 [nTPM]":"6.3","Tissue RNA - small intestine [nTPM]":"5.8","Tissue RNA - smooth muscle [nTPM]":"35.1","Tissue RNA - spinal cord [nTPM]":"3.6","Tissue RNA - spleen [nTPM]":"27.3","Tissue RNA - stomach 1 [nTPM]":"15.9","Tissue RNA - testis [nTPM]":"8.0","Tissue RNA - thalamus [nTPM]":"7.3","Tissue RNA - thymus [nTPM]":"28.3","Tissue RNA - thyroid gland [nTPM]":"8.7","Tissue RNA - tongue [nTPM]":"5.5","Tissue RNA - tonsil [nTPM]":"1.9","Tissue RNA - urinary bladder [nTPM]":"35.0","Tissue RNA - vagina [nTPM]":"6.7","Tissue RNA - white matter [nTPM]":"1.5","Cell RNA - A-431 [nTPM]":"7.0","Cell RNA - A549 [nTPM]":"71.9","Cell RNA - AF22 [nTPM]":"2.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"128.7","Cell RNA - ASC TERT1 [nTPM]":"136.8","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.6","Cell RNA - BJ hTERT+ [nTPM]":"4.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.3","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"30.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"19.1","Cell RNA - fHDF\/TERT166 [nTPM]":"17.8","Cell RNA - GAMG [nTPM]":"3.1","Cell RNA - HaCaT [nTPM]":"58.7","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"4.0","Cell RNA - HBF TERT88 [nTPM]":"2.3","Cell RNA - HDLM-2 [nTPM]":"5.5","Cell RNA - HEK 293 [nTPM]":"3.8","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"21.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"36.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"551.3","Cell RNA - hTCEpi [nTPM]":"55.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"30.7","Cell RNA - hTERT-HME1 [nTPM]":"1.4","Cell RNA - hTERT-RPE1 [nTPM]":"128.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.7","Cell RNA - MCF7 [nTPM]":"29.2","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"22.5","Cell RNA - NTERA-2 [nTPM]":"7.5","Cell RNA - OE19 [nTPM]":"10.4","Cell RNA - PC-3 [nTPM]":"14.2","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"13.4","Cell RNA - RT4 [nTPM]":"0.9","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"2.1","Cell RNA - SiHa [nTPM]":"270.0","Cell RNA - SK-BR-3 [nTPM]":"38.8","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"7.5","Cell RNA - T-47d [nTPM]":"49.4","Cell RNA - THP-1 [nTPM]":"10.8","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"1.1","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"107.9","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"142.2","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"11.8","Blood RNA - basophil [nTPM]":"1.6","Blood RNA - classical monocyte [nTPM]":"156.9","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"23.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"6.5","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"18.6","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"70.2","Brain RNA - amygdala [nTPM]":"2.7","Brain RNA - basal ganglia [nTPM]":"6.2","Brain RNA - cerebellum [nTPM]":"1.6","Brain RNA - cerebral cortex [nTPM]":"8.9","Brain RNA - hippocampal formation [nTPM]":"2.5","Brain RNA - hypothalamus [nTPM]":"2.3","Brain RNA - medulla oblongata [nTPM]":"3.6","Brain RNA - midbrain [nTPM]":"2.9","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"3.6","Brain RNA - thalamus [nTPM]":"7.3","Brain RNA - white matter [nTPM]":"1.5","Single Cell Type RNA - Adipocytes [nTPM]":"56.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"66.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"118.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"86.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"42.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"79.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"46.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"1.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"6.0","Single Cell Type RNA - Early spermatids [nTPM]":"15.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"100.4","Single Cell Type RNA - Endothelial cells [nTPM]":"103.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.8","Single Cell Type RNA - Fibroblasts [nTPM]":"114.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"28.2","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"12.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.3","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"103.0","Single Cell Type RNA - Langerhans cells [nTPM]":"50.6","Single Cell Type RNA - Late spermatids [nTPM]":"12.1","Single Cell Type RNA - Leydig cells [nTPM]":"159.7","Single Cell Type RNA - Macrophages [nTPM]":"112.2","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"64.6","Single Cell Type RNA - monocytes [nTPM]":"140.1","Single Cell Type RNA - Muller glia cells [nTPM]":"1.6","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"170.8","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"747.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.7","Single Cell Type RNA - Spermatocytes [nTPM]":"12.6","Single Cell Type RNA - Spermatogonia [nTPM]":"2.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"2.4","Single Cell Type RNA - Theca cells [nTPM]":"1.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.0","Single Cell Type RNA - Urothelial cells [nTPM]":"498.7"},{"Gene":"CYP21A2","Gene synonym":["CA21H","CAH1","CPS1","CYP21","CYP21B","P450c21B"],"Ensembl":"ENSG00000231852","Gene description":"Cytochrome P450 family 21 subfamily A member 2","Uniprot":["P08686"],"Chromosome":"6","Position":"32038327-32041644","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Steroidogenesis"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Congenital adrenal hyperplasia","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"46","RNA tissue specific nTPM":{"adrenal gland":"2041.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Hepatocytes":"15.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"2.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"3.3"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048979","HPA053371"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA048979":"AB_2680584","HPA053371":"AB_2682131"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Tissue RNA - adipose tissue [nTPM]":"2.0","Tissue RNA - adrenal gland [nTPM]":"2041.7","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.5","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"1.9","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"2.5","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"1.5","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"0.6","Tissue RNA - fallopian tube [nTPM]":"2.4","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"2.9","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"7.0","Tissue RNA - liver [nTPM]":"44.8","Tissue RNA - lung [nTPM]":"0.8","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"4.3","Tissue RNA - pancreas [nTPM]":"0.9","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.9","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"1.9","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"4.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"1.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"5.5","Tissue RNA - stomach 1 [nTPM]":"0.8","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"2.3","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"2.1","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"3.3","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.8","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.8","Single Cell Type RNA - Endothelial cells [nTPM]":"0.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"15.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"1.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CYP24A1","Gene synonym":["CP24","CYP24","P450-CC24"],"Ensembl":"ENSG00000019186","Gene description":"Cytochrome P450 family 24 subfamily A member 1","Uniprot":["Q07973"],"Chromosome":"20","Position":"54153446-54173986","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"endometrium 1":"14.9","kidney":"35.3","lymphoid tissue":"10.5","placenta":"10.0","urinary bladder":"28.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"48.3","Basal respiratory cells":"142.7","Basal squamous epithelial cells":"74.0","Club cells":"47.0","Proximal tubular cells":"61.3","Urothelial cells":"36.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"lung cancer":"18.3","urothelial cancer":"21.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"17","RNA cell line specific nTPM":{"A549":"411.5","Hep G2":"122.6"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022261","HPA063771"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA022261":"AB_1847427","HPA063771":"AB_2685120"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-7"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.69e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"3.7","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"1.7","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"14.9","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"3.8","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"1.8","Tissue RNA - kidney [nTPM]":"35.3","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"0.7","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"2.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"10.0","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"2.9","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"2.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"1.3","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"10.5","Tissue RNA - urinary bladder [nTPM]":"28.7","Tissue RNA - vagina [nTPM]":"1.3","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.5","Cell RNA - A549 [nTPM]":"411.5","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"2.7","Cell RNA - CAPAN-2 [nTPM]":"12.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"3.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.9","Cell RNA - HaCaT [nTPM]":"15.8","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"6.5","Cell RNA - Hep G2 [nTPM]":"122.6","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.9","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"11.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"7.0","Cell RNA - SCLC-21H [nTPM]":"1.3","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"2.6","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"16.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"1.8","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"2.0","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"22.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"48.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"142.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"74.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"47.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"2.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"61.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"19.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"36.7"},{"Gene":"CYP27A1","Gene synonym":["CP27","CTX","CYP27"],"Ensembl":"ENSG00000135929","Gene description":"Cytochrome P450 family 27 subfamily A member 1","Uniprot":["Q02318"],"Chromosome":"2","Position":"218781749-218815293","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol metabolism"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"liver":"594.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"404.3","Hofbauer cells":"148.9","Proximal enterocytes":"206.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"liver cancer":"176.9","melanoma":"85.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"classical monocyte":"151.5","neutrophil":"126.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"21","RNA blood lineage specific nTPM":{"granulocytes":"126.3","monocytes":"151.5"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"299.6","HSkMC":"54.7","RPTEC TERT1":"78.5","SK-MEL-30":"103.6","WM-115":"42.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059155"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA059155":"AB_2683933"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.05e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.62e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Tissue RNA - adipose tissue [nTPM]":"23.1","Tissue RNA - adrenal gland [nTPM]":"50.3","Tissue RNA - amygdala [nTPM]":"45.2","Tissue RNA - appendix [nTPM]":"15.7","Tissue RNA - basal ganglia [nTPM]":"59.0","Tissue RNA - bone marrow [nTPM]":"1.3","Tissue RNA - breast [nTPM]":"21.8","Tissue RNA - cerebellum [nTPM]":"57.0","Tissue RNA - cerebral cortex [nTPM]":"59.3","Tissue RNA - cervix [nTPM]":"27.6","Tissue RNA - choroid plexus [nTPM]":"75.6","Tissue RNA - colon [nTPM]":"27.6","Tissue RNA - duodenum [nTPM]":"77.8","Tissue RNA - endometrium 1 [nTPM]":"19.8","Tissue RNA - epididymis [nTPM]":"11.6","Tissue RNA - esophagus [nTPM]":"11.9","Tissue RNA - fallopian tube [nTPM]":"34.0","Tissue RNA - gallbladder [nTPM]":"19.1","Tissue RNA - heart muscle [nTPM]":"30.7","Tissue RNA - hippocampal formation [nTPM]":"42.2","Tissue RNA - hypothalamus [nTPM]":"49.3","Tissue RNA - kidney [nTPM]":"46.4","Tissue RNA - liver [nTPM]":"594.4","Tissue RNA - lung [nTPM]":"71.7","Tissue RNA - lymph node [nTPM]":"24.6","Tissue RNA - medulla oblongata [nTPM]":"63.0","Tissue RNA - midbrain [nTPM]":"56.1","Tissue RNA - ovary [nTPM]":"32.6","Tissue RNA - pancreas [nTPM]":"8.3","Tissue RNA - parathyroid gland [nTPM]":"18.5","Tissue RNA - pituitary gland [nTPM]":"29.6","Tissue RNA - placenta [nTPM]":"6.2","Tissue RNA - pons [nTPM]":"62.7","Tissue RNA - prostate [nTPM]":"41.8","Tissue RNA - rectum [nTPM]":"20.7","Tissue RNA - retina [nTPM]":"22.5","Tissue RNA - salivary gland [nTPM]":"40.4","Tissue RNA - seminal vesicle [nTPM]":"29.5","Tissue RNA - skeletal muscle [nTPM]":"37.9","Tissue RNA - skin 1 [nTPM]":"17.5","Tissue RNA - small intestine [nTPM]":"81.9","Tissue RNA - smooth muscle [nTPM]":"13.2","Tissue RNA - spinal cord [nTPM]":"50.6","Tissue RNA - spleen [nTPM]":"13.0","Tissue RNA - stomach 1 [nTPM]":"13.8","Tissue RNA - testis [nTPM]":"12.6","Tissue RNA - thalamus [nTPM]":"58.8","Tissue RNA - thymus [nTPM]":"23.6","Tissue RNA - thyroid gland [nTPM]":"12.6","Tissue RNA - tongue [nTPM]":"49.2","Tissue RNA - tonsil [nTPM]":"28.0","Tissue RNA - urinary bladder [nTPM]":"24.3","Tissue RNA - vagina [nTPM]":"23.2","Tissue RNA - white matter [nTPM]":"69.2","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"2.7","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"4.6","Cell RNA - ASC TERT1 [nTPM]":"3.3","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"1.9","Cell RNA - BJ hTERT+ [nTPM]":"11.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.8","Cell RNA - CACO-2 [nTPM]":"13.7","Cell RNA - CAPAN-2 [nTPM]":"0.8","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"4.3","Cell RNA - fHDF\/TERT166 [nTPM]":"7.6","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"1.7","Cell RNA - HDLM-2 [nTPM]":"1.4","Cell RNA - HEK 293 [nTPM]":"1.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"299.6","Cell RNA - HHSteC [nTPM]":"16.2","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"54.7","Cell RNA - hTCEpi [nTPM]":"0.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"12.8","Cell RNA - HUVEC TERT2 [nTPM]":"5.9","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"8.3","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"2.3","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"0.5","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"2.4","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"78.5","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"103.6","Cell RNA - SuSa [nTPM]":"2.4","Cell RNA - T-47d [nTPM]":"1.6","Cell RNA - THP-1 [nTPM]":"2.2","Cell RNA - TIME [nTPM]":"5.9","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"6.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"42.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"151.5","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"17.1","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"6.5","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"126.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"1.2","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"44.1","Brain RNA - amygdala [nTPM]":"45.2","Brain RNA - basal ganglia [nTPM]":"59.0","Brain RNA - cerebellum [nTPM]":"57.0","Brain RNA - cerebral cortex [nTPM]":"59.3","Brain RNA - hippocampal formation [nTPM]":"42.2","Brain RNA - hypothalamus [nTPM]":"49.3","Brain RNA - medulla oblongata [nTPM]":"63.0","Brain RNA - midbrain [nTPM]":"56.1","Brain RNA - pons [nTPM]":"62.7","Brain RNA - spinal cord [nTPM]":"50.6","Brain RNA - thalamus [nTPM]":"58.8","Brain RNA - white matter [nTPM]":"69.2","Single Cell Type RNA - Adipocytes [nTPM]":"10.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"28.9","Single Cell Type RNA - Astrocytes [nTPM]":"33.6","Single Cell Type RNA - B-cells [nTPM]":"0.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"52.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.6","Single Cell Type RNA - Bipolar cells [nTPM]":"15.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"11.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"37.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"12.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.3","Single Cell Type RNA - Endothelial cells [nTPM]":"10.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"24.5","Single Cell Type RNA - Erythroid cells [nTPM]":"8.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"35.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.8","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"1.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.6","Single Cell Type RNA - Hepatocytes [nTPM]":"404.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"148.9","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"18.2","Single Cell Type RNA - Langerhans cells [nTPM]":"5.1","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"47.5","Single Cell Type RNA - Macrophages [nTPM]":"104.3","Single Cell Type RNA - Melanocytes [nTPM]":"49.8","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"92.4","Single Cell Type RNA - Muller glia cells [nTPM]":"28.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"26.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"108.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.7","Single Cell Type RNA - Paneth cells [nTPM]":"44.0","Single Cell Type RNA - Peritubular cells [nTPM]":"26.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"43.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"206.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"76.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - T-cells [nTPM]":"2.3","Single Cell Type RNA - Theca cells [nTPM]":"1.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"30.3","Single Cell Type RNA - Urothelial cells [nTPM]":"20.4"},{"Gene":"CYP27B1","Gene synonym":["CYP1","P450c1","PDDR","VDD1"],"Ensembl":"ENSG00000111012","Gene description":"Cytochrome P450 family 27 subfamily B member 1","Uniprot":["O15528"],"Chromosome":"12","Position":"57762334-57768986","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"15.2","thyroid gland":"5.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Exocrine glandular cells":"22.1","monocytes":"22.8","Proximal tubular cells":"36.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"MAIT T-cell":"1.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"T-cells":"1.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTERT-HME1":"13.6","RH-30":"22.6"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.79e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.9","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.7","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.8","Tissue RNA - breast [nTPM]":"0.8","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"15.2","Tissue RNA - liver [nTPM]":"0.6","Tissue RNA - lung [nTPM]":"0.5","Tissue RNA - lymph node [nTPM]":"0.9","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"1.6","Tissue RNA - parathyroid gland [nTPM]":"1.0","Tissue RNA - pituitary gland [nTPM]":"0.4","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.6","Tissue RNA - retina [nTPM]":"3.3","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"5.7","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.7","Tissue RNA - urinary bladder [nTPM]":"2.2","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"2.8","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"1.1","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"3.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"3.7","Cell RNA - CAPAN-2 [nTPM]":"1.0","Cell RNA - Daudi [nTPM]":"2.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"3.3","Cell RNA - HAP1 [nTPM]":"0.5","Cell RNA - HBEC3-KT [nTPM]":"5.9","Cell RNA - HBF TERT88 [nTPM]":"3.1","Cell RNA - HDLM-2 [nTPM]":"0.6","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.9","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"1.0","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"1.2","Cell RNA - HMC-1 [nTPM]":"2.5","Cell RNA - HSkMC [nTPM]":"0.5","Cell RNA - hTCEpi [nTPM]":"1.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.8","Cell RNA - hTERT-HME1 [nTPM]":"13.6","Cell RNA - hTERT-RPE1 [nTPM]":"1.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.4","Cell RNA - JURKAT [nTPM]":"2.6","Cell RNA - K-562 [nTPM]":"1.3","Cell RNA - Karpas-707 [nTPM]":"1.2","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"1.1","Cell RNA - NTERA-2 [nTPM]":"1.3","Cell RNA - OE19 [nTPM]":"2.8","Cell RNA - PC-3 [nTPM]":"2.3","Cell RNA - REH [nTPM]":"0.8","Cell RNA - RH-30 [nTPM]":"22.6","Cell RNA - RPMI-8226 [nTPM]":"1.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.5","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"0.8","Cell RNA - SiHa [nTPM]":"2.0","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"1.7","Cell RNA - THP-1 [nTPM]":"2.3","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"1.6","Cell RNA - U-2197 [nTPM]":"1.1","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"1.4","Cell RNA - U-266\/84 [nTPM]":"1.2","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"1.2","Cell RNA - U-937 [nTPM]":"2.6","Cell RNA - WM-115 [nTPM]":"1.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"1.2","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"3.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"1.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"22.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.7","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"22.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"1.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"36.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.9","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"CYP2R1","Gene synonym":[],"Ensembl":"ENSG00000186104","Gene description":"Cytochrome P450 family 2 subfamily R member 1","Uniprot":["Q6VVX0"],"Chromosome":"11","Position":"14877440-14892231","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"176.3","Late spermatids":"106.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"26.0"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042949"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 23: Spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042949":"AB_2678237"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.86e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.5","Tissue RNA - adrenal gland [nTPM]":"1.8","Tissue RNA - amygdala [nTPM]":"1.6","Tissue RNA - appendix [nTPM]":"3.1","Tissue RNA - basal ganglia [nTPM]":"1.9","Tissue RNA - bone marrow [nTPM]":"3.0","Tissue RNA - breast [nTPM]":"4.1","Tissue RNA - cerebellum [nTPM]":"4.9","Tissue RNA - cerebral cortex [nTPM]":"2.4","Tissue RNA - cervix [nTPM]":"2.6","Tissue RNA - choroid plexus [nTPM]":"0.5","Tissue RNA - colon [nTPM]":"3.7","Tissue RNA - duodenum [nTPM]":"4.6","Tissue RNA - endometrium 1 [nTPM]":"2.2","Tissue RNA - epididymis [nTPM]":"3.2","Tissue RNA - esophagus [nTPM]":"4.6","Tissue RNA - fallopian tube [nTPM]":"1.8","Tissue RNA - gallbladder [nTPM]":"1.6","Tissue RNA - heart muscle [nTPM]":"2.2","Tissue RNA - hippocampal formation [nTPM]":"1.6","Tissue RNA - hypothalamus [nTPM]":"2.1","Tissue RNA - kidney [nTPM]":"1.8","Tissue RNA - liver [nTPM]":"2.2","Tissue RNA - lung [nTPM]":"2.5","Tissue RNA - lymph node [nTPM]":"3.0","Tissue RNA - medulla oblongata [nTPM]":"1.7","Tissue RNA - midbrain [nTPM]":"1.5","Tissue RNA - ovary [nTPM]":"2.0","Tissue RNA - pancreas [nTPM]":"5.2","Tissue RNA - parathyroid gland [nTPM]":"1.5","Tissue RNA - pituitary gland [nTPM]":"2.6","Tissue RNA - placenta [nTPM]":"1.0","Tissue RNA - pons [nTPM]":"1.8","Tissue RNA - prostate [nTPM]":"2.8","Tissue RNA - rectum [nTPM]":"3.3","Tissue RNA - retina [nTPM]":"3.3","Tissue RNA - salivary gland [nTPM]":"4.5","Tissue RNA - seminal vesicle [nTPM]":"1.4","Tissue RNA - skeletal muscle [nTPM]":"2.8","Tissue RNA - skin 1 [nTPM]":"6.9","Tissue RNA - small intestine [nTPM]":"4.4","Tissue RNA - smooth muscle [nTPM]":"1.5","Tissue RNA - spinal cord [nTPM]":"1.5","Tissue RNA - spleen [nTPM]":"3.0","Tissue RNA - stomach 1 [nTPM]":"5.0","Tissue RNA - testis [nTPM]":"4.3","Tissue RNA - thalamus [nTPM]":"1.6","Tissue RNA - thymus [nTPM]":"2.4","Tissue RNA - thyroid gland [nTPM]":"1.9","Tissue RNA - tongue [nTPM]":"1.6","Tissue RNA - tonsil [nTPM]":"2.9","Tissue RNA - urinary bladder [nTPM]":"3.0","Tissue RNA - vagina [nTPM]":"3.3","Tissue RNA - white matter [nTPM]":"2.3","Cell RNA - A-431 [nTPM]":"6.1","Cell RNA - A549 [nTPM]":"3.7","Cell RNA - AF22 [nTPM]":"3.6","Cell RNA - AN3-CA [nTPM]":"1.5","Cell RNA - ASC diff [nTPM]":"1.5","Cell RNA - ASC TERT1 [nTPM]":"2.5","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"2.1","Cell RNA - BJ hTERT+ [nTPM]":"1.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.3","Cell RNA - CACO-2 [nTPM]":"4.3","Cell RNA - CAPAN-2 [nTPM]":"6.8","Cell RNA - Daudi [nTPM]":"7.6","Cell RNA - EFO-21 [nTPM]":"1.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"4.7","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"1.2","Cell RNA - HBEC3-KT [nTPM]":"2.8","Cell RNA - HBF TERT88 [nTPM]":"0.5","Cell RNA - HDLM-2 [nTPM]":"6.3","Cell RNA - HEK 293 [nTPM]":"5.8","Cell RNA - HEL [nTPM]":"3.4","Cell RNA - HeLa [nTPM]":"4.7","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"5.4","Cell RNA - HL-60 [nTPM]":"5.9","Cell RNA - HMC-1 [nTPM]":"3.4","Cell RNA - HSkMC [nTPM]":"2.4","Cell RNA - hTCEpi [nTPM]":"10.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"4.4","Cell RNA - hTERT-RPE1 [nTPM]":"1.1","Cell RNA - HUVEC TERT2 [nTPM]":"1.4","Cell RNA - JURKAT [nTPM]":"9.3","Cell RNA - K-562 [nTPM]":"5.1","Cell RNA - Karpas-707 [nTPM]":"26.0","Cell RNA - LHCN-M2 [nTPM]":"0.8","Cell RNA - MCF7 [nTPM]":"1.6","Cell RNA - MOLT-4 [nTPM]":"6.5","Cell RNA - NB-4 [nTPM]":"11.9","Cell RNA - NTERA-2 [nTPM]":"3.4","Cell RNA - OE19 [nTPM]":"4.4","Cell RNA - PC-3 [nTPM]":"3.5","Cell RNA - REH [nTPM]":"4.6","Cell RNA - RH-30 [nTPM]":"2.6","Cell RNA - RPMI-8226 [nTPM]":"11.6","Cell RNA - RPTEC TERT1 [nTPM]":"1.4","Cell RNA - RT4 [nTPM]":"0.7","Cell RNA - SCLC-21H [nTPM]":"3.0","Cell RNA - SH-SY5Y [nTPM]":"4.7","Cell RNA - SiHa [nTPM]":"4.5","Cell RNA - SK-BR-3 [nTPM]":"5.4","Cell RNA - SK-MEL-30 [nTPM]":"5.2","Cell RNA - SuSa [nTPM]":"2.3","Cell RNA - T-47d [nTPM]":"4.0","Cell RNA - THP-1 [nTPM]":"2.2","Cell RNA - TIME [nTPM]":"3.8","Cell RNA - U-138 MG [nTPM]":"3.6","Cell RNA - U-2 OS [nTPM]":"4.4","Cell RNA - U-2197 [nTPM]":"2.2","Cell RNA - U-251 MG [nTPM]":"2.7","Cell RNA - U-266\/70 [nTPM]":"12.8","Cell RNA - U-266\/84 [nTPM]":"16.1","Cell RNA - U-698 [nTPM]":"9.0","Cell RNA - U-87 MG [nTPM]":"5.0","Cell RNA - U-937 [nTPM]":"7.6","Cell RNA - WM-115 [nTPM]":"3.3","Blood RNA - basophil [nTPM]":"2.4","Blood RNA - classical monocyte [nTPM]":"2.0","Blood RNA - eosinophil [nTPM]":"1.6","Blood RNA - gdT-cell [nTPM]":"3.0","Blood RNA - intermediate monocyte [nTPM]":"1.9","Blood RNA - MAIT T-cell [nTPM]":"4.7","Blood RNA - memory B-cell [nTPM]":"1.6","Blood RNA - memory CD4 T-cell [nTPM]":"2.5","Blood RNA - memory CD8 T-cell [nTPM]":"1.9","Blood RNA - myeloid DC [nTPM]":"1.7","Blood RNA - naive B-cell [nTPM]":"2.8","Blood RNA - naive CD4 T-cell [nTPM]":"3.5","Blood RNA - naive CD8 T-cell [nTPM]":"3.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"2.1","Blood RNA - non-classical monocyte [nTPM]":"2.3","Blood RNA - plasmacytoid DC [nTPM]":"2.0","Blood RNA - T-reg [nTPM]":"3.6","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"1.6","Brain RNA - basal ganglia [nTPM]":"1.9","Brain RNA - cerebellum [nTPM]":"4.9","Brain RNA - cerebral cortex [nTPM]":"2.4","Brain RNA - hippocampal formation [nTPM]":"1.6","Brain RNA - hypothalamus [nTPM]":"2.1","Brain RNA - medulla oblongata [nTPM]":"1.7","Brain RNA - midbrain [nTPM]":"1.5","Brain RNA - pons [nTPM]":"1.8","Brain RNA - spinal cord [nTPM]":"1.5","Brain RNA - thalamus [nTPM]":"1.6","Brain RNA - white matter [nTPM]":"2.3","Single Cell Type RNA - Adipocytes [nTPM]":"4.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"8.5","Single Cell Type RNA - B-cells [nTPM]":"15.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Bipolar cells [nTPM]":"1.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"7.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"9.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.1","Single Cell Type RNA - Early spermatids [nTPM]":"176.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.3","Single Cell Type RNA - Endothelial cells [nTPM]":"6.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"4.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"4.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.9","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"7.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"6.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.9","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"7.6","Single Cell Type RNA - Langerhans cells [nTPM]":"12.6","Single Cell Type RNA - Late spermatids [nTPM]":"106.7","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"7.7","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"6.1","Single Cell Type RNA - Muller glia cells [nTPM]":"5.0","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"13.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.3","Single Cell Type RNA - Paneth cells [nTPM]":"2.9","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"11.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.9","Single Cell Type RNA - Spermatocytes [nTPM]":"23.8","Single Cell Type RNA - Spermatogonia [nTPM]":"20.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"16.4","Single Cell Type RNA - Theca cells [nTPM]":"6.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.8","Single Cell Type RNA - Urothelial cells [nTPM]":"6.1"},{"Gene":"CYP2U1","Gene synonym":["SPG49","SPG56"],"Ensembl":"ENSG00000155016","Gene description":"Cytochrome P450 family 2 subfamily U member 1","Uniprot":["Q7Z449"],"Chromosome":"4","Position":"107931549-107953461","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"lymphoid tissue":"84.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"30.2","Inhibitory neurons":"34.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"2.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041622","HPA046754","HPA064827"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Vesicles"],"Antibody RRID":{"HPA041622":"AB_2677583","HPA046754":"AB_2679787","HPA064827":"AB_2685362"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.75e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.97e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.7","Tissue RNA - adrenal gland [nTPM]":"6.4","Tissue RNA - amygdala [nTPM]":"6.6","Tissue RNA - appendix [nTPM]":"4.0","Tissue RNA - basal ganglia [nTPM]":"8.3","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"4.5","Tissue RNA - cerebellum [nTPM]":"7.6","Tissue RNA - cerebral cortex [nTPM]":"7.3","Tissue RNA - cervix [nTPM]":"5.1","Tissue RNA - choroid plexus [nTPM]":"10.1","Tissue RNA - colon [nTPM]":"5.8","Tissue RNA - duodenum [nTPM]":"3.4","Tissue RNA - endometrium 1 [nTPM]":"6.6","Tissue RNA - epididymis [nTPM]":"3.6","Tissue RNA - esophagus [nTPM]":"3.5","Tissue RNA - fallopian tube [nTPM]":"7.8","Tissue RNA - gallbladder [nTPM]":"5.6","Tissue RNA - heart muscle [nTPM]":"7.7","Tissue RNA - hippocampal formation [nTPM]":"6.5","Tissue RNA - hypothalamus [nTPM]":"8.7","Tissue RNA - kidney [nTPM]":"5.3","Tissue RNA - liver [nTPM]":"5.9","Tissue RNA - lung [nTPM]":"5.7","Tissue RNA - lymph node [nTPM]":"6.3","Tissue RNA - medulla oblongata [nTPM]":"9.0","Tissue RNA - midbrain [nTPM]":"7.9","Tissue RNA - ovary [nTPM]":"9.5","Tissue RNA - pancreas [nTPM]":"2.3","Tissue RNA - parathyroid gland [nTPM]":"10.7","Tissue RNA - pituitary gland [nTPM]":"4.7","Tissue RNA - placenta [nTPM]":"2.4","Tissue RNA - pons [nTPM]":"8.2","Tissue RNA - prostate [nTPM]":"9.9","Tissue RNA - rectum [nTPM]":"3.9","Tissue RNA - retina [nTPM]":"5.8","Tissue RNA - salivary gland [nTPM]":"3.4","Tissue RNA - seminal vesicle [nTPM]":"8.7","Tissue RNA - skeletal muscle [nTPM]":"3.6","Tissue RNA - skin 1 [nTPM]":"2.7","Tissue RNA - small intestine [nTPM]":"4.7","Tissue RNA - smooth muscle [nTPM]":"10.2","Tissue RNA - spinal cord [nTPM]":"8.1","Tissue RNA - spleen [nTPM]":"7.6","Tissue RNA - stomach 1 [nTPM]":"3.2","Tissue RNA - testis [nTPM]":"3.0","Tissue RNA - thalamus [nTPM]":"8.0","Tissue RNA - thymus [nTPM]":"84.9","Tissue RNA - thyroid gland [nTPM]":"3.6","Tissue RNA - tongue [nTPM]":"7.2","Tissue RNA - tonsil [nTPM]":"4.7","Tissue RNA - urinary bladder [nTPM]":"4.7","Tissue RNA - vagina [nTPM]":"3.8","Tissue RNA - white matter [nTPM]":"9.5","Cell RNA - A-431 [nTPM]":"4.0","Cell RNA - A549 [nTPM]":"1.9","Cell RNA - AF22 [nTPM]":"5.2","Cell RNA - AN3-CA [nTPM]":"9.5","Cell RNA - ASC diff [nTPM]":"28.6","Cell RNA - ASC TERT1 [nTPM]":"13.4","Cell RNA - BEWO [nTPM]":"0.8","Cell RNA - BJ [nTPM]":"16.8","Cell RNA - BJ hTERT+ [nTPM]":"25.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.7","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"2.5","Cell RNA - Daudi [nTPM]":"10.8","Cell RNA - EFO-21 [nTPM]":"1.1","Cell RNA - fHDF\/TERT166 [nTPM]":"10.1","Cell RNA - GAMG [nTPM]":"7.8","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"8.1","Cell RNA - HBEC3-KT [nTPM]":"6.4","Cell RNA - HBF TERT88 [nTPM]":"15.4","Cell RNA - HDLM-2 [nTPM]":"3.0","Cell RNA - HEK 293 [nTPM]":"2.5","Cell RNA - HEL [nTPM]":"2.3","Cell RNA - HeLa [nTPM]":"3.5","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"11.3","Cell RNA - HL-60 [nTPM]":"3.2","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"15.3","Cell RNA - hTCEpi [nTPM]":"5.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.7","Cell RNA - hTERT-HME1 [nTPM]":"3.2","Cell RNA - hTERT-RPE1 [nTPM]":"20.8","Cell RNA - HUVEC TERT2 [nTPM]":"4.0","Cell RNA - JURKAT [nTPM]":"12.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"5.0","Cell RNA - LHCN-M2 [nTPM]":"8.4","Cell RNA - MCF7 [nTPM]":"2.9","Cell RNA - MOLT-4 [nTPM]":"11.8","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"5.4","Cell RNA - OE19 [nTPM]":"0.4","Cell RNA - PC-3 [nTPM]":"4.7","Cell RNA - REH [nTPM]":"6.5","Cell RNA - RH-30 [nTPM]":"6.3","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"3.3","Cell RNA - RT4 [nTPM]":"6.7","Cell RNA - SCLC-21H [nTPM]":"10.0","Cell RNA - SH-SY5Y [nTPM]":"7.6","Cell RNA - SiHa [nTPM]":"4.2","Cell RNA - SK-BR-3 [nTPM]":"7.3","Cell RNA - SK-MEL-30 [nTPM]":"18.6","Cell RNA - SuSa [nTPM]":"4.3","Cell RNA - T-47d [nTPM]":"3.6","Cell RNA - THP-1 [nTPM]":"1.5","Cell RNA - TIME [nTPM]":"10.6","Cell RNA - U-138 MG [nTPM]":"6.5","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"9.3","Cell RNA - U-251 MG [nTPM]":"6.9","Cell RNA - U-266\/70 [nTPM]":"21.1","Cell RNA - U-266\/84 [nTPM]":"21.2","Cell RNA - U-698 [nTPM]":"3.4","Cell RNA - U-87 MG [nTPM]":"5.5","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"7.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.9","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"2.8","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"6.6","Brain RNA - basal ganglia [nTPM]":"8.3","Brain RNA - cerebellum [nTPM]":"7.6","Brain RNA - cerebral cortex [nTPM]":"7.3","Brain RNA - hippocampal formation [nTPM]":"6.5","Brain RNA - hypothalamus [nTPM]":"8.7","Brain RNA - medulla oblongata [nTPM]":"9.0","Brain RNA - midbrain [nTPM]":"7.9","Brain RNA - pons [nTPM]":"8.2","Brain RNA - spinal cord [nTPM]":"8.1","Brain RNA - thalamus [nTPM]":"8.0","Brain RNA - white matter [nTPM]":"9.5","Single Cell Type RNA - Adipocytes [nTPM]":"5.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.9","Single Cell Type RNA - Astrocytes [nTPM]":"18.6","Single Cell Type RNA - B-cells [nTPM]":"12.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Bipolar cells [nTPM]":"4.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"2.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"10.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.9","Single Cell Type RNA - Early spermatids [nTPM]":"13.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.3","Single Cell Type RNA - Endothelial cells [nTPM]":"5.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"30.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"12.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.2","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"2.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.6","Single Cell Type RNA - Hepatocytes [nTPM]":"7.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.3","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"34.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"6.2","Single Cell Type RNA - Langerhans cells [nTPM]":"3.3","Single Cell Type RNA - Late spermatids [nTPM]":"9.5","Single Cell Type RNA - Leydig cells [nTPM]":"17.7","Single Cell Type RNA - Macrophages [nTPM]":"4.7","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"3.7","Single Cell Type RNA - Muller glia cells [nTPM]":"9.5","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"17.7","Single Cell Type RNA - Plasma cells [nTPM]":"4.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"4.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"3.6","Single Cell Type RNA - Theca cells [nTPM]":"5.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"CYP3A4","Gene synonym":["CYP3A3"],"Ensembl":"ENSG00000160868","Gene description":"Cytochrome P450 family 3 subfamily A member 4","Uniprot":["P08684"],"Chromosome":"7","Position":"99756960-99784248","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol metabolism"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"liver":"3796.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"40","RNA single cell type specific nTPM":{"Hepatocytes":"2612.9","Proximal enterocytes":"1685.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"240","RNA cancer specific FPKM":{"liver cancer":"351.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"2.0","NB-4":"2.2","RPMI-8226":"3.4","SCLC-21H":"1.3","SH-SY5Y":"2.0"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033671","HPA072245","HPA075539"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB033671":"AB_782375","HPA072245":null,"HPA075539":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.27e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"3.8","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"1.1","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.8","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"4.6","Tissue RNA - duodenum [nTPM]":"797.6","Tissue RNA - endometrium 1 [nTPM]":"0.6","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.6","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"4.9","Tissue RNA - liver [nTPM]":"3796.2","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.9","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"43.4","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"2.2","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"2.4","Tissue RNA - skin 1 [nTPM]":"1.9","Tissue RNA - small intestine [nTPM]":"853.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"1.1","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"2.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.8","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"2.2","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.8","Cell RNA - RPMI-8226 [nTPM]":"3.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"1.3","Cell RNA - SH-SY5Y [nTPM]":"2.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.7","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.5","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.8","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"26.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"30.0","Single Cell Type RNA - Hepatocytes [nTPM]":"2612.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"29.6","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"52.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"38.9","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1685.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"2.3","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.1","Single Cell Type RNA - Urothelial cells [nTPM]":"1.1"},{"Gene":"CYP4F2","Gene synonym":[],"Ensembl":"ENSG00000186115","Gene description":"Cytochrome P450 family 4 subfamily F member 2","Uniprot":["P78329"],"Chromosome":"19","Position":"15878023-15898077","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"80.2","kidney":"40.9","liver":"166.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hepatocytes":"139.7","Proximal enterocytes":"204.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"liver cancer":"29.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"19","RNA blood cell specific nTPM":{"basophil":"8.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"82","RNA blood lineage specific nTPM":{"granulocytes":"8.1"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Hep G2":"3.8"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014048","HPA017265","HPA058960"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014048":"AB_1847452","HPA017265":"AB_1847451","HPA058960":"AB_2683862"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"1.1","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.5","Tissue RNA - colon [nTPM]":"2.2","Tissue RNA - duodenum [nTPM]":"79.9","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"25.8","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"3.3","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"40.9","Tissue RNA - liver [nTPM]":"166.7","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"6.6","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.8","Tissue RNA - small intestine [nTPM]":"80.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.6","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.8","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"3.8","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"8.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"5.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"5.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"139.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"18.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"9.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"204.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"37.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"CYP4V2","Gene synonym":["CYP4AH1"],"Ensembl":"ENSG00000145476","Gene description":"Cytochrome P450 family 4 subfamily V member 2","Uniprot":["Q6ZWL3"],"Chromosome":"4","Position":"186191567-186213463","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Sensory transduction","Vision"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Corneal dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"113.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"103.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"15.2","SK-MEL-30":"27.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029122"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA029122":"AB_10601806"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.86e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.85e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.49e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.4","Tissue RNA - adrenal gland [nTPM]":"16.4","Tissue RNA - amygdala [nTPM]":"5.1","Tissue RNA - appendix [nTPM]":"5.2","Tissue RNA - basal ganglia [nTPM]":"6.8","Tissue RNA - bone marrow [nTPM]":"2.1","Tissue RNA - breast [nTPM]":"5.7","Tissue RNA - cerebellum [nTPM]":"5.6","Tissue RNA - cerebral cortex [nTPM]":"5.0","Tissue RNA - cervix [nTPM]":"8.6","Tissue RNA - choroid plexus [nTPM]":"17.9","Tissue RNA - colon [nTPM]":"9.6","Tissue RNA - duodenum [nTPM]":"16.5","Tissue RNA - endometrium 1 [nTPM]":"5.6","Tissue RNA - epididymis [nTPM]":"2.6","Tissue RNA - esophagus [nTPM]":"5.0","Tissue RNA - fallopian tube [nTPM]":"6.1","Tissue RNA - gallbladder [nTPM]":"14.7","Tissue RNA - heart muscle [nTPM]":"9.2","Tissue RNA - hippocampal formation [nTPM]":"4.8","Tissue RNA - hypothalamus [nTPM]":"5.1","Tissue RNA - kidney [nTPM]":"33.9","Tissue RNA - liver [nTPM]":"113.5","Tissue RNA - lung [nTPM]":"10.8","Tissue RNA - lymph node [nTPM]":"5.6","Tissue RNA - medulla oblongata [nTPM]":"5.3","Tissue RNA - midbrain [nTPM]":"6.0","Tissue RNA - ovary [nTPM]":"5.7","Tissue RNA - pancreas [nTPM]":"15.6","Tissue RNA - parathyroid gland [nTPM]":"33.4","Tissue RNA - pituitary gland [nTPM]":"3.7","Tissue RNA - placenta [nTPM]":"3.5","Tissue RNA - pons [nTPM]":"5.3","Tissue RNA - prostate [nTPM]":"8.2","Tissue RNA - rectum [nTPM]":"11.9","Tissue RNA - retina [nTPM]":"14.2","Tissue RNA - salivary gland [nTPM]":"7.0","Tissue RNA - seminal vesicle [nTPM]":"7.5","Tissue RNA - skeletal muscle [nTPM]":"4.5","Tissue RNA - skin 1 [nTPM]":"1.3","Tissue RNA - small intestine [nTPM]":"16.7","Tissue RNA - smooth muscle [nTPM]":"7.1","Tissue RNA - spinal cord [nTPM]":"5.4","Tissue RNA - spleen [nTPM]":"11.2","Tissue RNA - stomach 1 [nTPM]":"6.2","Tissue RNA - testis [nTPM]":"3.2","Tissue RNA - thalamus [nTPM]":"5.6","Tissue RNA - thymus [nTPM]":"6.5","Tissue RNA - thyroid gland [nTPM]":"17.3","Tissue RNA - tongue [nTPM]":"5.0","Tissue RNA - tonsil [nTPM]":"4.9","Tissue RNA - urinary bladder [nTPM]":"6.4","Tissue RNA - vagina [nTPM]":"2.3","Tissue RNA - white matter [nTPM]":"6.3","Cell RNA - A-431 [nTPM]":"3.4","Cell RNA - A549 [nTPM]":"1.8","Cell RNA - AF22 [nTPM]":"0.8","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"15.2","Cell RNA - ASC TERT1 [nTPM]":"6.3","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"4.4","Cell RNA - BJ hTERT+ [nTPM]":"9.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.9","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"13.0","Cell RNA - Daudi [nTPM]":"1.1","Cell RNA - EFO-21 [nTPM]":"0.5","Cell RNA - fHDF\/TERT166 [nTPM]":"3.5","Cell RNA - GAMG [nTPM]":"5.9","Cell RNA - HaCaT [nTPM]":"1.6","Cell RNA - HAP1 [nTPM]":"1.9","Cell RNA - HBEC3-KT [nTPM]":"1.7","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"6.0","Cell RNA - HEK 293 [nTPM]":"2.2","Cell RNA - HEL [nTPM]":"4.7","Cell RNA - HeLa [nTPM]":"0.8","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"5.6","Cell RNA - HL-60 [nTPM]":"2.6","Cell RNA - HMC-1 [nTPM]":"1.9","Cell RNA - HSkMC [nTPM]":"5.8","Cell RNA - hTCEpi [nTPM]":"0.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.9","Cell RNA - hTERT-HME1 [nTPM]":"1.0","Cell RNA - hTERT-RPE1 [nTPM]":"5.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"6.4","Cell RNA - K-562 [nTPM]":"1.4","Cell RNA - Karpas-707 [nTPM]":"14.3","Cell RNA - LHCN-M2 [nTPM]":"6.8","Cell RNA - MCF7 [nTPM]":"2.9","Cell RNA - MOLT-4 [nTPM]":"3.6","Cell RNA - NB-4 [nTPM]":"1.3","Cell RNA - NTERA-2 [nTPM]":"1.5","Cell RNA - OE19 [nTPM]":"1.6","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"3.1","Cell RNA - RH-30 [nTPM]":"0.7","Cell RNA - RPMI-8226 [nTPM]":"1.0","Cell RNA - RPTEC TERT1 [nTPM]":"7.4","Cell RNA - RT4 [nTPM]":"6.1","Cell RNA - SCLC-21H [nTPM]":"4.0","Cell RNA - SH-SY5Y [nTPM]":"4.9","Cell RNA - SiHa [nTPM]":"1.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"27.5","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"2.6","Cell RNA - THP-1 [nTPM]":"4.6","Cell RNA - TIME [nTPM]":"4.1","Cell RNA - U-138 MG [nTPM]":"3.6","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"3.5","Cell RNA - U-251 MG [nTPM]":"1.6","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"10.9","Cell RNA - U-937 [nTPM]":"11.0","Cell RNA - WM-115 [nTPM]":"4.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.8","Blood RNA - intermediate monocyte [nTPM]":"1.9","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.4","Blood RNA - memory CD8 T-cell [nTPM]":"1.8","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"1.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"3.1","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"1.1","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"5.1","Brain RNA - basal ganglia [nTPM]":"6.8","Brain RNA - cerebellum [nTPM]":"5.6","Brain RNA - cerebral cortex [nTPM]":"5.0","Brain RNA - hippocampal formation [nTPM]":"4.8","Brain RNA - hypothalamus [nTPM]":"5.1","Brain RNA - medulla oblongata [nTPM]":"5.3","Brain RNA - midbrain [nTPM]":"6.0","Brain RNA - pons [nTPM]":"5.3","Brain RNA - spinal cord [nTPM]":"5.4","Brain RNA - thalamus [nTPM]":"5.6","Brain RNA - white matter [nTPM]":"6.3","Single Cell Type RNA - Adipocytes [nTPM]":"9.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.5","Single Cell Type RNA - Astrocytes [nTPM]":"31.3","Single Cell Type RNA - B-cells [nTPM]":"13.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"33.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"42.9","Single Cell Type RNA - Club cells [nTPM]":"8.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.0","Single Cell Type RNA - dendritic cells [nTPM]":"9.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"24.2","Single Cell Type RNA - Early spermatids [nTPM]":"2.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.1","Single Cell Type RNA - Endothelial cells [nTPM]":"7.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.9","Single Cell Type RNA - Erythroid cells [nTPM]":"16.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"22.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.1","Single Cell Type RNA - Fibroblasts [nTPM]":"14.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.6","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"6.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.9","Single Cell Type RNA - Hepatocytes [nTPM]":"103.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.5","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"23.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.5","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"14.8","Single Cell Type RNA - Langerhans cells [nTPM]":"6.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.1","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"11.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"3.5","Single Cell Type RNA - Muller glia cells [nTPM]":"52.2","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.6","Single Cell Type RNA - Paneth cells [nTPM]":"9.0","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"12.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"47.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"28.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"27.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.6","Single Cell Type RNA - Spermatocytes [nTPM]":"8.9","Single Cell Type RNA - Spermatogonia [nTPM]":"6.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"17.2","Single Cell Type RNA - Theca cells [nTPM]":"6.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.5","Single Cell Type RNA - Urothelial cells [nTPM]":"5.7"},{"Gene":"CYP7B1","Gene synonym":["SPG5A"],"Ensembl":"ENSG00000172817","Gene description":"Cytochrome P450 family 7 subfamily B member 1","Uniprot":["O75881"],"Chromosome":"8","Position":"64587763-64798737","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol metabolism"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Intrahepatic cholestasis","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"27.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"93.7","Oligodendrocyte precursor cells":"94.5","Oligodendrocytes":"119.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"11","RNA blood cell specific nTPM":{"basophil":"2.5","eosinophil":"1.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"25","RNA blood lineage specific nTPM":{"granulocytes":"2.5"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"HSkMC":"16.5","SH-SY5Y":"5.5","WM-115":"10.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017761"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017761":"AB_1847455"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-3"},"Tissue RNA - adipose tissue [nTPM]":"8.4","Tissue RNA - adrenal gland [nTPM]":"5.4","Tissue RNA - amygdala [nTPM]":"5.7","Tissue RNA - appendix [nTPM]":"5.6","Tissue RNA - basal ganglia [nTPM]":"11.4","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"6.3","Tissue RNA - cerebellum [nTPM]":"8.2","Tissue RNA - cerebral cortex [nTPM]":"6.6","Tissue RNA - cervix [nTPM]":"5.7","Tissue RNA - choroid plexus [nTPM]":"8.6","Tissue RNA - colon [nTPM]":"2.3","Tissue RNA - duodenum [nTPM]":"1.8","Tissue RNA - endometrium 1 [nTPM]":"2.8","Tissue RNA - epididymis [nTPM]":"2.0","Tissue RNA - esophagus [nTPM]":"7.3","Tissue RNA - fallopian tube [nTPM]":"2.7","Tissue RNA - gallbladder [nTPM]":"5.8","Tissue RNA - heart muscle [nTPM]":"3.6","Tissue RNA - hippocampal formation [nTPM]":"5.3","Tissue RNA - hypothalamus [nTPM]":"6.8","Tissue RNA - kidney [nTPM]":"7.9","Tissue RNA - liver [nTPM]":"21.5","Tissue RNA - lung [nTPM]":"4.6","Tissue RNA - lymph node [nTPM]":"2.4","Tissue RNA - medulla oblongata [nTPM]":"11.8","Tissue RNA - midbrain [nTPM]":"7.3","Tissue RNA - ovary [nTPM]":"4.2","Tissue RNA - pancreas [nTPM]":"6.7","Tissue RNA - parathyroid gland [nTPM]":"11.4","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"11.4","Tissue RNA - prostate [nTPM]":"4.4","Tissue RNA - rectum [nTPM]":"3.5","Tissue RNA - retina [nTPM]":"1.9","Tissue RNA - salivary gland [nTPM]":"4.6","Tissue RNA - seminal vesicle [nTPM]":"5.6","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"5.9","Tissue RNA - small intestine [nTPM]":"1.8","Tissue RNA - smooth muscle [nTPM]":"4.3","Tissue RNA - spinal cord [nTPM]":"8.4","Tissue RNA - spleen [nTPM]":"9.2","Tissue RNA - stomach 1 [nTPM]":"2.4","Tissue RNA - testis [nTPM]":"1.7","Tissue RNA - thalamus [nTPM]":"8.1","Tissue RNA - thymus [nTPM]":"2.1","Tissue RNA - thyroid gland [nTPM]":"12.2","Tissue RNA - tongue [nTPM]":"1.7","Tissue RNA - tonsil [nTPM]":"2.9","Tissue RNA - urinary bladder [nTPM]":"7.9","Tissue RNA - vagina [nTPM]":"3.0","Tissue RNA - white matter [nTPM]":"27.2","Cell RNA - A-431 [nTPM]":"1.5","Cell RNA - A549 [nTPM]":"0.6","Cell RNA - AF22 [nTPM]":"1.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"16.5","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"2.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.5","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.6","Cell RNA - SH-SY5Y [nTPM]":"5.5","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"2.2","Cell RNA - SuSa [nTPM]":"0.8","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"1.4","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"10.3","Blood RNA - basophil [nTPM]":"2.5","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"1.5","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"5.7","Brain RNA - basal ganglia [nTPM]":"11.4","Brain RNA - cerebellum [nTPM]":"8.2","Brain RNA - cerebral cortex [nTPM]":"6.6","Brain RNA - hippocampal formation [nTPM]":"5.3","Brain RNA - hypothalamus [nTPM]":"6.8","Brain RNA - medulla oblongata [nTPM]":"11.8","Brain RNA - midbrain [nTPM]":"7.3","Brain RNA - pons [nTPM]":"11.4","Brain RNA - spinal cord [nTPM]":"8.4","Brain RNA - thalamus [nTPM]":"8.1","Brain RNA - white matter [nTPM]":"27.2","Single Cell Type RNA - Adipocytes [nTPM]":"3.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.4","Single Cell Type RNA - Astrocytes [nTPM]":"93.7","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"4.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"0.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.4","Single Cell Type RNA - Early spermatids [nTPM]":"7.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.9","Single Cell Type RNA - Endothelial cells [nTPM]":"2.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"29.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"15.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"12.7","Single Cell Type RNA - Granulosa cells [nTPM]":"0.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"8.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"30.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"4.9","Single Cell Type RNA - Late spermatids [nTPM]":"8.6","Single Cell Type RNA - Leydig cells [nTPM]":"5.9","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"30.0","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"6.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"94.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"119.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.8","Single Cell Type RNA - Spermatocytes [nTPM]":"4.1","Single Cell Type RNA - Spermatogonia [nTPM]":"3.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.3","Single Cell Type RNA - Theca cells [nTPM]":"7.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"3.1"},{"Gene":"DAG1","Gene synonym":["156DAG","A3a","AGRNR","DAG"],"Ensembl":"ENSG00000173402","Gene description":"Dystroglycan 1","Uniprot":["Q14118"],"Chromosome":"3","Position":"49468703-49535618","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Congenital muscular dystrophy","Disease variant","Dystroglycanopathy","Limb-girdle muscular dystrophy","Lissencephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"207.9","Skeletal myocytes":"326.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"280.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB001960","CAB016353","HPA070563"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"84000000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB001960":null,"CAB016353":"AB_627292","HPA070563":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.59e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Tissue RNA - adipose tissue [nTPM]":"25.2","Tissue RNA - adrenal gland [nTPM]":"22.0","Tissue RNA - amygdala [nTPM]":"31.5","Tissue RNA - appendix [nTPM]":"17.9","Tissue RNA - basal ganglia [nTPM]":"32.6","Tissue RNA - bone marrow [nTPM]":"5.4","Tissue RNA - breast [nTPM]":"26.6","Tissue RNA - cerebellum [nTPM]":"30.7","Tissue RNA - cerebral cortex [nTPM]":"30.7","Tissue RNA - cervix [nTPM]":"26.2","Tissue RNA - choroid plexus [nTPM]":"25.5","Tissue RNA - colon [nTPM]":"38.8","Tissue RNA - duodenum [nTPM]":"24.0","Tissue RNA - endometrium 1 [nTPM]":"32.1","Tissue RNA - epididymis [nTPM]":"16.2","Tissue RNA - esophagus [nTPM]":"28.3","Tissue RNA - fallopian tube [nTPM]":"31.8","Tissue RNA - gallbladder [nTPM]":"26.4","Tissue RNA - heart muscle [nTPM]":"68.9","Tissue RNA - hippocampal formation [nTPM]":"30.1","Tissue RNA - hypothalamus [nTPM]":"28.9","Tissue RNA - kidney [nTPM]":"28.1","Tissue RNA - liver [nTPM]":"43.0","Tissue RNA - lung [nTPM]":"31.8","Tissue RNA - lymph node [nTPM]":"9.4","Tissue RNA - medulla oblongata [nTPM]":"33.3","Tissue RNA - midbrain [nTPM]":"31.4","Tissue RNA - ovary [nTPM]":"24.6","Tissue RNA - pancreas [nTPM]":"51.4","Tissue RNA - parathyroid gland [nTPM]":"44.3","Tissue RNA - pituitary gland [nTPM]":"18.6","Tissue RNA - placenta [nTPM]":"77.0","Tissue RNA - pons [nTPM]":"28.6","Tissue RNA - prostate [nTPM]":"29.5","Tissue RNA - rectum [nTPM]":"30.6","Tissue RNA - retina [nTPM]":"9.8","Tissue RNA - salivary gland [nTPM]":"31.8","Tissue RNA - seminal vesicle [nTPM]":"37.9","Tissue RNA - skeletal muscle [nTPM]":"93.8","Tissue RNA - skin 1 [nTPM]":"28.5","Tissue RNA - small intestine [nTPM]":"24.0","Tissue RNA - smooth muscle [nTPM]":"45.9","Tissue RNA - spinal cord [nTPM]":"30.2","Tissue RNA - spleen [nTPM]":"12.6","Tissue RNA - stomach 1 [nTPM]":"32.0","Tissue RNA - testis [nTPM]":"26.9","Tissue RNA - thalamus [nTPM]":"34.1","Tissue RNA - thymus [nTPM]":"10.5","Tissue RNA - thyroid gland [nTPM]":"25.5","Tissue RNA - tongue [nTPM]":"95.7","Tissue RNA - tonsil [nTPM]":"14.3","Tissue RNA - urinary bladder [nTPM]":"27.8","Tissue RNA - vagina [nTPM]":"22.0","Tissue RNA - white matter [nTPM]":"31.2","Cell RNA - A-431 [nTPM]":"92.3","Cell RNA - A549 [nTPM]":"92.4","Cell RNA - AF22 [nTPM]":"61.9","Cell RNA - AN3-CA [nTPM]":"152.3","Cell RNA - ASC diff [nTPM]":"80.3","Cell RNA - ASC TERT1 [nTPM]":"38.8","Cell RNA - BEWO [nTPM]":"280.9","Cell RNA - BJ [nTPM]":"63.9","Cell RNA - BJ hTERT+ [nTPM]":"93.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"108.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"69.0","Cell RNA - CACO-2 [nTPM]":"74.2","Cell RNA - CAPAN-2 [nTPM]":"96.0","Cell RNA - Daudi [nTPM]":"13.0","Cell RNA - EFO-21 [nTPM]":"62.2","Cell RNA - fHDF\/TERT166 [nTPM]":"103.2","Cell RNA - GAMG [nTPM]":"87.6","Cell RNA - HaCaT [nTPM]":"168.4","Cell RNA - HAP1 [nTPM]":"55.6","Cell RNA - HBEC3-KT [nTPM]":"81.2","Cell RNA - HBF TERT88 [nTPM]":"67.2","Cell RNA - HDLM-2 [nTPM]":"12.7","Cell RNA - HEK 293 [nTPM]":"18.6","Cell RNA - HEL [nTPM]":"9.6","Cell RNA - HeLa [nTPM]":"84.3","Cell RNA - Hep G2 [nTPM]":"87.2","Cell RNA - HHSteC [nTPM]":"35.5","Cell RNA - HL-60 [nTPM]":"11.2","Cell RNA - HMC-1 [nTPM]":"17.4","Cell RNA - HSkMC [nTPM]":"33.3","Cell RNA - hTCEpi [nTPM]":"72.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"100.3","Cell RNA - hTERT-HME1 [nTPM]":"33.3","Cell RNA - hTERT-RPE1 [nTPM]":"96.7","Cell RNA - HUVEC TERT2 [nTPM]":"97.1","Cell RNA - JURKAT [nTPM]":"15.3","Cell RNA - K-562 [nTPM]":"14.5","Cell RNA - Karpas-707 [nTPM]":"9.8","Cell RNA - LHCN-M2 [nTPM]":"31.2","Cell RNA - MCF7 [nTPM]":"75.5","Cell RNA - MOLT-4 [nTPM]":"10.1","Cell RNA - NB-4 [nTPM]":"8.1","Cell RNA - NTERA-2 [nTPM]":"66.4","Cell RNA - OE19 [nTPM]":"110.0","Cell RNA - PC-3 [nTPM]":"31.2","Cell RNA - REH [nTPM]":"5.5","Cell RNA - RH-30 [nTPM]":"60.5","Cell RNA - RPMI-8226 [nTPM]":"22.3","Cell RNA - RPTEC TERT1 [nTPM]":"82.5","Cell RNA - RT4 [nTPM]":"126.4","Cell RNA - SCLC-21H [nTPM]":"21.8","Cell RNA - SH-SY5Y [nTPM]":"45.2","Cell RNA - SiHa [nTPM]":"74.8","Cell RNA - SK-BR-3 [nTPM]":"206.0","Cell RNA - SK-MEL-30 [nTPM]":"105.5","Cell RNA - SuSa [nTPM]":"170.3","Cell RNA - T-47d [nTPM]":"171.6","Cell RNA - THP-1 [nTPM]":"22.8","Cell RNA - TIME [nTPM]":"51.8","Cell RNA - U-138 MG [nTPM]":"39.1","Cell RNA - U-2 OS [nTPM]":"63.9","Cell RNA - U-2197 [nTPM]":"76.0","Cell RNA - U-251 MG [nTPM]":"91.4","Cell RNA - U-266\/70 [nTPM]":"11.0","Cell RNA - U-266\/84 [nTPM]":"24.2","Cell RNA - U-698 [nTPM]":"8.1","Cell RNA - U-87 MG [nTPM]":"50.4","Cell RNA - U-937 [nTPM]":"12.6","Cell RNA - WM-115 [nTPM]":"245.9","Blood RNA - basophil [nTPM]":"2.3","Blood RNA - classical monocyte [nTPM]":"1.2","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"1.1","Blood RNA - intermediate monocyte [nTPM]":"1.3","Blood RNA - MAIT T-cell [nTPM]":"1.2","Blood RNA - memory B-cell [nTPM]":"1.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.0","Blood RNA - neutrophil [nTPM]":"2.2","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"2.5","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"31.5","Brain RNA - basal ganglia [nTPM]":"32.6","Brain RNA - cerebellum [nTPM]":"30.7","Brain RNA - cerebral cortex [nTPM]":"30.7","Brain RNA - hippocampal formation [nTPM]":"30.1","Brain RNA - hypothalamus [nTPM]":"28.9","Brain RNA - medulla oblongata [nTPM]":"33.3","Brain RNA - midbrain [nTPM]":"31.4","Brain RNA - pons [nTPM]":"28.6","Brain RNA - spinal cord [nTPM]":"30.2","Brain RNA - thalamus [nTPM]":"34.1","Brain RNA - white matter [nTPM]":"31.2","Single Cell Type RNA - Adipocytes [nTPM]":"19.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"54.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.4","Single Cell Type RNA - Astrocytes [nTPM]":"32.0","Single Cell Type RNA - B-cells [nTPM]":"4.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"31.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Bipolar cells [nTPM]":"7.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"36.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"46.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"56.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"20.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"35.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"116.4","Single Cell Type RNA - dendritic cells [nTPM]":"5.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"37.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"32.4","Single Cell Type RNA - Early spermatids [nTPM]":"30.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"30.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.3","Single Cell Type RNA - Endothelial cells [nTPM]":"20.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"33.0","Single Cell Type RNA - Erythroid cells [nTPM]":"14.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"79.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"118.4","Single Cell Type RNA - Fibroblasts [nTPM]":"26.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"37.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"37.9","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"207.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.8","Single Cell Type RNA - Hepatocytes [nTPM]":"59.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"21.2","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"16.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"29.7","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"8.6","Single Cell Type RNA - Langerhans cells [nTPM]":"7.0","Single Cell Type RNA - Late spermatids [nTPM]":"20.0","Single Cell Type RNA - Leydig cells [nTPM]":"21.5","Single Cell Type RNA - Macrophages [nTPM]":"6.3","Single Cell Type RNA - Melanocytes [nTPM]":"33.8","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"5.6","Single Cell Type RNA - Muller glia cells [nTPM]":"27.1","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"57.2","Single Cell Type RNA - Paneth cells [nTPM]":"21.4","Single Cell Type RNA - Peritubular cells [nTPM]":"36.9","Single Cell Type RNA - Plasma cells [nTPM]":"5.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.7","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"326.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"36.2","Single Cell Type RNA - Spermatocytes [nTPM]":"7.1","Single Cell Type RNA - Spermatogonia [nTPM]":"19.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"95.9","Single Cell Type RNA - T-cells [nTPM]":"5.9","Single Cell Type RNA - Theca cells [nTPM]":"10.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"29.2","Single Cell Type RNA - Urothelial cells [nTPM]":"10.2"},{"Gene":"DAO","Gene synonym":["DAAO","DAMOX"],"Ensembl":"ENSG00000110887","Gene description":"D-amino acid oxidase","Uniprot":["P14920"],"Chromosome":"12","Position":"108858932-108901043","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Schizophrenia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"71.4","kidney":"90.3","liver":"149.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Hepatocytes":"46.1","Proximal tubular cells":"86.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"liver cancer":"13.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"1.1"},"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"10","RNA mouse brain regional specific nTPM":{"cerebellum":"66.4","pons and medulla":"20.2"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038653","HPA038654"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038653":"AB_10673016","HPA038654":"AB_10673285"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.11e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.9","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"6.9","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"71.4","Tissue RNA - cerebral cortex [nTPM]":"1.6","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.5","Tissue RNA - colon [nTPM]":"1.4","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.8","Tissue RNA - hypothalamus [nTPM]":"3.3","Tissue RNA - kidney [nTPM]":"90.3","Tissue RNA - liver [nTPM]":"149.9","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"41.9","Tissue RNA - midbrain [nTPM]":"14.8","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"29.5","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"2.0","Tissue RNA - retina [nTPM]":"12.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"44.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"4.3","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"59.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"1.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.9","Brain RNA - basal ganglia [nTPM]":"6.9","Brain RNA - cerebellum [nTPM]":"71.4","Brain RNA - cerebral cortex [nTPM]":"1.6","Brain RNA - hippocampal formation [nTPM]":"0.8","Brain RNA - hypothalamus [nTPM]":"3.3","Brain RNA - medulla oblongata [nTPM]":"41.9","Brain RNA - midbrain [nTPM]":"14.8","Brain RNA - pons [nTPM]":"29.5","Brain RNA - spinal cord [nTPM]":"44.0","Brain RNA - thalamus [nTPM]":"4.3","Brain RNA - white matter [nTPM]":"59.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"1.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"46.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"86.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.7","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"DARS1","Gene synonym":["DARS"],"Ensembl":"ENSG00000115866","Gene description":"Aspartyl-tRNA synthetase 1","Uniprot":["P14868"],"Chromosome":"2","Position":"135905881-135986100","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cardiomyocytes":"85.1","Cytotrophoblasts":"115.4","Extravillous trophoblasts":"157.9","Hofbauer cells":"94.2","Syncytiotrophoblasts":"136.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020451","HPA029804","HPA029805"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"210000","Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA020451":"AB_1847479","HPA029804":"AB_10599178","HPA029805":"AB_10601994"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.39e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.57e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.00e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.54e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.24e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Tissue RNA - adipose tissue [nTPM]":"37.5","Tissue RNA - adrenal gland [nTPM]":"42.1","Tissue RNA - amygdala [nTPM]":"30.1","Tissue RNA - appendix [nTPM]":"41.2","Tissue RNA - basal ganglia [nTPM]":"31.2","Tissue RNA - bone marrow [nTPM]":"34.0","Tissue RNA - breast [nTPM]":"48.7","Tissue RNA - cerebellum [nTPM]":"33.3","Tissue RNA - cerebral cortex [nTPM]":"52.1","Tissue RNA - cervix [nTPM]":"34.7","Tissue RNA - choroid plexus [nTPM]":"28.0","Tissue RNA - colon [nTPM]":"38.5","Tissue RNA - duodenum [nTPM]":"23.5","Tissue RNA - endometrium 1 [nTPM]":"38.4","Tissue RNA - epididymis [nTPM]":"22.8","Tissue RNA - esophagus [nTPM]":"46.0","Tissue RNA - fallopian tube [nTPM]":"37.8","Tissue RNA - gallbladder [nTPM]":"25.8","Tissue RNA - heart muscle [nTPM]":"42.3","Tissue RNA - hippocampal formation [nTPM]":"29.5","Tissue RNA - hypothalamus [nTPM]":"35.2","Tissue RNA - kidney [nTPM]":"47.3","Tissue RNA - liver [nTPM]":"44.2","Tissue RNA - lung [nTPM]":"27.8","Tissue RNA - lymph node [nTPM]":"48.3","Tissue RNA - medulla oblongata [nTPM]":"32.6","Tissue RNA - midbrain [nTPM]":"31.2","Tissue RNA - ovary [nTPM]":"47.2","Tissue RNA - pancreas [nTPM]":"36.1","Tissue RNA - parathyroid gland [nTPM]":"38.4","Tissue RNA - pituitary gland [nTPM]":"24.6","Tissue RNA - placenta [nTPM]":"44.4","Tissue RNA - pons [nTPM]":"35.6","Tissue RNA - prostate [nTPM]":"33.6","Tissue RNA - rectum [nTPM]":"26.6","Tissue RNA - retina [nTPM]":"87.1","Tissue RNA - salivary gland [nTPM]":"32.5","Tissue RNA - seminal vesicle [nTPM]":"36.5","Tissue RNA - skeletal muscle [nTPM]":"82.8","Tissue RNA - skin 1 [nTPM]":"40.2","Tissue RNA - small intestine [nTPM]":"28.0","Tissue RNA - smooth muscle [nTPM]":"39.3","Tissue RNA - spinal cord [nTPM]":"34.0","Tissue RNA - spleen [nTPM]":"32.3","Tissue RNA - stomach 1 [nTPM]":"33.3","Tissue RNA - testis [nTPM]":"17.8","Tissue RNA - thalamus [nTPM]":"30.7","Tissue RNA - thymus [nTPM]":"63.1","Tissue RNA - thyroid gland [nTPM]":"43.4","Tissue RNA - tongue [nTPM]":"60.1","Tissue RNA - tonsil [nTPM]":"55.4","Tissue RNA - urinary bladder [nTPM]":"40.0","Tissue RNA - vagina [nTPM]":"36.4","Tissue RNA - white matter [nTPM]":"35.3","Cell RNA - A-431 [nTPM]":"201.6","Cell RNA - A549 [nTPM]":"77.0","Cell RNA - AF22 [nTPM]":"73.4","Cell RNA - AN3-CA [nTPM]":"66.3","Cell RNA - ASC diff [nTPM]":"61.0","Cell RNA - ASC TERT1 [nTPM]":"78.1","Cell RNA - BEWO [nTPM]":"141.6","Cell RNA - BJ [nTPM]":"99.8","Cell RNA - BJ hTERT+ [nTPM]":"92.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"92.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"91.1","Cell RNA - CACO-2 [nTPM]":"163.0","Cell RNA - CAPAN-2 [nTPM]":"84.0","Cell RNA - Daudi [nTPM]":"210.0","Cell RNA - EFO-21 [nTPM]":"159.8","Cell RNA - fHDF\/TERT166 [nTPM]":"78.4","Cell RNA - GAMG [nTPM]":"86.6","Cell RNA - HaCaT [nTPM]":"111.7","Cell RNA - HAP1 [nTPM]":"94.9","Cell RNA - HBEC3-KT [nTPM]":"114.9","Cell RNA - HBF TERT88 [nTPM]":"170.3","Cell RNA - HDLM-2 [nTPM]":"95.6","Cell RNA - HEK 293 [nTPM]":"86.0","Cell RNA - HEL [nTPM]":"134.0","Cell RNA - HeLa [nTPM]":"76.8","Cell RNA - Hep G2 [nTPM]":"185.6","Cell RNA - HHSteC [nTPM]":"83.9","Cell RNA - HL-60 [nTPM]":"188.3","Cell RNA - HMC-1 [nTPM]":"90.8","Cell RNA - HSkMC [nTPM]":"84.5","Cell RNA - hTCEpi [nTPM]":"75.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"109.1","Cell RNA - hTERT-HME1 [nTPM]":"99.8","Cell RNA - hTERT-RPE1 [nTPM]":"122.9","Cell RNA - HUVEC TERT2 [nTPM]":"46.8","Cell RNA - JURKAT [nTPM]":"106.3","Cell RNA - K-562 [nTPM]":"131.6","Cell RNA - Karpas-707 [nTPM]":"66.0","Cell RNA - LHCN-M2 [nTPM]":"66.6","Cell RNA - MCF7 [nTPM]":"87.3","Cell RNA - MOLT-4 [nTPM]":"139.2","Cell RNA - NB-4 [nTPM]":"117.4","Cell RNA - NTERA-2 [nTPM]":"77.8","Cell RNA - OE19 [nTPM]":"85.3","Cell RNA - PC-3 [nTPM]":"66.9","Cell RNA - REH [nTPM]":"179.3","Cell RNA - RH-30 [nTPM]":"157.9","Cell RNA - RPMI-8226 [nTPM]":"139.0","Cell RNA - RPTEC TERT1 [nTPM]":"91.8","Cell RNA - RT4 [nTPM]":"76.9","Cell RNA - SCLC-21H [nTPM]":"40.3","Cell RNA - SH-SY5Y [nTPM]":"89.6","Cell RNA - SiHa [nTPM]":"75.0","Cell RNA - SK-BR-3 [nTPM]":"63.5","Cell RNA - SK-MEL-30 [nTPM]":"74.8","Cell RNA - SuSa [nTPM]":"72.2","Cell RNA - T-47d [nTPM]":"66.8","Cell RNA - THP-1 [nTPM]":"118.2","Cell RNA - TIME [nTPM]":"38.2","Cell RNA - U-138 MG [nTPM]":"86.0","Cell RNA - U-2 OS [nTPM]":"87.4","Cell RNA - U-2197 [nTPM]":"64.5","Cell RNA - U-251 MG [nTPM]":"92.8","Cell RNA - U-266\/70 [nTPM]":"194.9","Cell RNA - U-266\/84 [nTPM]":"123.3","Cell RNA - U-698 [nTPM]":"250.2","Cell RNA - U-87 MG [nTPM]":"144.1","Cell RNA - U-937 [nTPM]":"132.3","Cell RNA - WM-115 [nTPM]":"51.0","Blood RNA - basophil [nTPM]":"33.7","Blood RNA - classical monocyte [nTPM]":"85.4","Blood RNA - eosinophil [nTPM]":"51.2","Blood RNA - gdT-cell [nTPM]":"115.2","Blood RNA - intermediate monocyte [nTPM]":"82.6","Blood RNA - MAIT T-cell [nTPM]":"174.7","Blood RNA - memory B-cell [nTPM]":"219.9","Blood RNA - memory CD4 T-cell [nTPM]":"172.6","Blood RNA - memory CD8 T-cell [nTPM]":"151.4","Blood RNA - myeloid DC [nTPM]":"133.7","Blood RNA - naive B-cell [nTPM]":"198.8","Blood RNA - naive CD4 T-cell [nTPM]":"175.2","Blood RNA - naive CD8 T-cell [nTPM]":"154.2","Blood RNA - neutrophil [nTPM]":"31.7","Blood RNA - NK-cell [nTPM]":"171.9","Blood RNA - non-classical monocyte [nTPM]":"67.4","Blood RNA - plasmacytoid DC [nTPM]":"130.4","Blood RNA - T-reg [nTPM]":"168.9","Blood RNA - total PBMC [nTPM]":"153.3","Brain RNA - amygdala [nTPM]":"30.1","Brain RNA - basal ganglia [nTPM]":"31.2","Brain RNA - cerebellum [nTPM]":"33.3","Brain RNA - cerebral cortex [nTPM]":"52.1","Brain RNA - hippocampal formation [nTPM]":"29.5","Brain RNA - hypothalamus [nTPM]":"35.2","Brain RNA - medulla oblongata [nTPM]":"32.6","Brain RNA - midbrain [nTPM]":"31.2","Brain RNA - pons [nTPM]":"35.6","Brain RNA - spinal cord [nTPM]":"34.0","Brain RNA - thalamus [nTPM]":"30.7","Brain RNA - white matter [nTPM]":"35.3","Single Cell Type RNA - Adipocytes [nTPM]":"29.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"8.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"85.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"115.4","Single Cell Type RNA - dendritic cells [nTPM]":"20.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"8.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"157.9","Single Cell Type RNA - Fibroblasts [nTPM]":"18.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"94.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"6.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"11.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"136.4","Single Cell Type RNA - T-cells [nTPM]":"4.4","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"DARS2","Gene synonym":["FLJ10514","mtAspRS"],"Ensembl":"ENSG00000117593","Gene description":"Aspartyl-tRNA synthetase 2, mitochondrial","Uniprot":["Q6PI48"],"Chromosome":"1","Position":"173824653-173858808","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026506","HPA026528"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA026506":"AB_1847482","HPA026528":"AB_1847483"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.74e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-3"},"Tissue RNA - adipose tissue [nTPM]":"8.8","Tissue RNA - adrenal gland [nTPM]":"9.8","Tissue RNA - amygdala [nTPM]":"3.1","Tissue RNA - appendix [nTPM]":"7.6","Tissue RNA - basal ganglia [nTPM]":"3.5","Tissue RNA - bone marrow [nTPM]":"5.4","Tissue RNA - breast [nTPM]":"7.5","Tissue RNA - cerebellum [nTPM]":"3.7","Tissue RNA - cerebral cortex [nTPM]":"4.3","Tissue RNA - cervix [nTPM]":"7.1","Tissue RNA - choroid plexus [nTPM]":"11.5","Tissue RNA - colon [nTPM]":"14.6","Tissue RNA - duodenum [nTPM]":"8.7","Tissue RNA - endometrium 1 [nTPM]":"4.3","Tissue RNA - epididymis [nTPM]":"4.7","Tissue RNA - esophagus [nTPM]":"6.4","Tissue RNA - fallopian tube [nTPM]":"5.2","Tissue RNA - gallbladder [nTPM]":"4.8","Tissue RNA - heart muscle [nTPM]":"8.4","Tissue RNA - hippocampal formation [nTPM]":"3.1","Tissue RNA - hypothalamus [nTPM]":"3.8","Tissue RNA - kidney [nTPM]":"19.9","Tissue RNA - liver [nTPM]":"13.5","Tissue RNA - lung [nTPM]":"5.7","Tissue RNA - lymph node [nTPM]":"9.2","Tissue RNA - medulla oblongata [nTPM]":"3.3","Tissue RNA - midbrain [nTPM]":"3.6","Tissue RNA - ovary [nTPM]":"4.4","Tissue RNA - pancreas [nTPM]":"5.7","Tissue RNA - parathyroid gland [nTPM]":"15.5","Tissue RNA - pituitary gland [nTPM]":"2.9","Tissue RNA - placenta [nTPM]":"7.6","Tissue RNA - pons [nTPM]":"3.4","Tissue RNA - prostate [nTPM]":"5.3","Tissue RNA - rectum [nTPM]":"15.4","Tissue RNA - retina [nTPM]":"5.2","Tissue RNA - salivary gland [nTPM]":"5.2","Tissue RNA - seminal vesicle [nTPM]":"5.0","Tissue RNA - skeletal muscle [nTPM]":"5.6","Tissue RNA - skin 1 [nTPM]":"3.4","Tissue RNA - small intestine [nTPM]":"10.4","Tissue RNA - smooth muscle [nTPM]":"5.6","Tissue RNA - spinal cord [nTPM]":"3.5","Tissue RNA - spleen [nTPM]":"6.2","Tissue RNA - stomach 1 [nTPM]":"9.3","Tissue RNA - testis [nTPM]":"6.2","Tissue RNA - thalamus [nTPM]":"3.9","Tissue RNA - thymus [nTPM]":"10.6","Tissue RNA - thyroid gland [nTPM]":"7.6","Tissue RNA - tongue [nTPM]":"13.5","Tissue RNA - tonsil [nTPM]":"12.0","Tissue RNA - urinary bladder [nTPM]":"6.7","Tissue RNA - vagina [nTPM]":"4.1","Tissue RNA - white matter [nTPM]":"3.7","Cell RNA - A-431 [nTPM]":"74.8","Cell RNA - A549 [nTPM]":"50.5","Cell RNA - AF22 [nTPM]":"26.3","Cell RNA - AN3-CA [nTPM]":"18.7","Cell RNA - ASC diff [nTPM]":"24.0","Cell RNA - ASC TERT1 [nTPM]":"34.2","Cell RNA - BEWO [nTPM]":"38.6","Cell RNA - BJ [nTPM]":"32.3","Cell RNA - BJ hTERT+ [nTPM]":"30.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"49.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"37.0","Cell RNA - CACO-2 [nTPM]":"47.5","Cell RNA - CAPAN-2 [nTPM]":"68.2","Cell RNA - Daudi [nTPM]":"41.6","Cell RNA - EFO-21 [nTPM]":"45.2","Cell RNA - fHDF\/TERT166 [nTPM]":"27.2","Cell RNA - GAMG [nTPM]":"31.3","Cell RNA - HaCaT [nTPM]":"77.5","Cell RNA - HAP1 [nTPM]":"86.6","Cell RNA - HBEC3-KT [nTPM]":"56.5","Cell RNA - HBF TERT88 [nTPM]":"66.7","Cell RNA - HDLM-2 [nTPM]":"48.6","Cell RNA - HEK 293 [nTPM]":"41.5","Cell RNA - HEL [nTPM]":"35.2","Cell RNA - HeLa [nTPM]":"22.7","Cell RNA - Hep G2 [nTPM]":"31.8","Cell RNA - HHSteC [nTPM]":"24.0","Cell RNA - HL-60 [nTPM]":"30.9","Cell RNA - HMC-1 [nTPM]":"30.8","Cell RNA - HSkMC [nTPM]":"23.2","Cell RNA - hTCEpi [nTPM]":"25.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"50.9","Cell RNA - hTERT-HME1 [nTPM]":"44.5","Cell RNA - hTERT-RPE1 [nTPM]":"15.4","Cell RNA - HUVEC TERT2 [nTPM]":"49.8","Cell RNA - JURKAT [nTPM]":"30.5","Cell RNA - K-562 [nTPM]":"74.7","Cell RNA - Karpas-707 [nTPM]":"31.0","Cell RNA - LHCN-M2 [nTPM]":"39.6","Cell RNA - MCF7 [nTPM]":"19.9","Cell RNA - MOLT-4 [nTPM]":"38.8","Cell RNA - NB-4 [nTPM]":"16.1","Cell RNA - NTERA-2 [nTPM]":"60.2","Cell RNA - OE19 [nTPM]":"83.0","Cell RNA - PC-3 [nTPM]":"63.2","Cell RNA - REH [nTPM]":"44.3","Cell RNA - RH-30 [nTPM]":"40.6","Cell RNA - RPMI-8226 [nTPM]":"78.2","Cell RNA - RPTEC TERT1 [nTPM]":"43.7","Cell RNA - RT4 [nTPM]":"24.9","Cell RNA - SCLC-21H [nTPM]":"40.4","Cell RNA - SH-SY5Y [nTPM]":"34.2","Cell RNA - SiHa [nTPM]":"36.3","Cell RNA - SK-BR-3 [nTPM]":"79.6","Cell RNA - SK-MEL-30 [nTPM]":"51.3","Cell RNA - SuSa [nTPM]":"47.0","Cell RNA - T-47d [nTPM]":"84.5","Cell RNA - THP-1 [nTPM]":"39.7","Cell RNA - TIME [nTPM]":"21.2","Cell RNA - U-138 MG [nTPM]":"22.9","Cell RNA - U-2 OS [nTPM]":"35.3","Cell RNA - U-2197 [nTPM]":"32.6","Cell RNA - U-251 MG [nTPM]":"52.5","Cell RNA - U-266\/70 [nTPM]":"21.7","Cell RNA - U-266\/84 [nTPM]":"60.4","Cell RNA - U-698 [nTPM]":"46.3","Cell RNA - U-87 MG [nTPM]":"13.3","Cell RNA - U-937 [nTPM]":"33.3","Cell RNA - WM-115 [nTPM]":"51.5","Blood RNA - basophil [nTPM]":"3.9","Blood RNA - classical monocyte [nTPM]":"4.4","Blood RNA - eosinophil [nTPM]":"3.3","Blood RNA - gdT-cell [nTPM]":"3.8","Blood RNA - intermediate monocyte [nTPM]":"7.0","Blood RNA - MAIT T-cell [nTPM]":"5.4","Blood RNA - memory B-cell [nTPM]":"6.0","Blood RNA - memory CD4 T-cell [nTPM]":"3.4","Blood RNA - memory CD8 T-cell [nTPM]":"3.2","Blood RNA - myeloid DC [nTPM]":"6.4","Blood RNA - naive B-cell [nTPM]":"4.4","Blood RNA - naive CD4 T-cell [nTPM]":"3.8","Blood RNA - naive CD8 T-cell [nTPM]":"2.6","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"3.5","Blood RNA - non-classical monocyte [nTPM]":"5.0","Blood RNA - plasmacytoid DC [nTPM]":"2.5","Blood RNA - T-reg [nTPM]":"3.9","Blood RNA - total PBMC [nTPM]":"3.5","Brain RNA - amygdala [nTPM]":"3.1","Brain RNA - basal ganglia [nTPM]":"3.5","Brain RNA - cerebellum [nTPM]":"3.7","Brain RNA - cerebral cortex [nTPM]":"4.3","Brain RNA - hippocampal formation [nTPM]":"3.1","Brain RNA - hypothalamus [nTPM]":"3.8","Brain RNA - medulla oblongata [nTPM]":"3.3","Brain RNA - midbrain [nTPM]":"3.6","Brain RNA - pons [nTPM]":"3.4","Brain RNA - spinal cord [nTPM]":"3.5","Brain RNA - thalamus [nTPM]":"3.9","Brain RNA - white matter [nTPM]":"3.7","Single Cell Type RNA - Adipocytes [nTPM]":"3.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.1","Single Cell Type RNA - Astrocytes [nTPM]":"7.2","Single Cell Type RNA - B-cells [nTPM]":"5.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"2.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"4.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.7","Single Cell Type RNA - dendritic cells [nTPM]":"3.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.9","Single Cell Type RNA - Early spermatids [nTPM]":"2.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.9","Single Cell Type RNA - Endothelial cells [nTPM]":"4.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"9.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"16.0","Single Cell Type RNA - Fibroblasts [nTPM]":"3.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.5","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"4.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"5.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.3","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.4","Single Cell Type RNA - Langerhans cells [nTPM]":"2.2","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"5.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"5.6","Single Cell Type RNA - Muller glia cells [nTPM]":"2.9","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.8","Single Cell Type RNA - Paneth cells [nTPM]":"1.9","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"7.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.0","Single Cell Type RNA - Spermatocytes [nTPM]":"8.9","Single Cell Type RNA - Spermatogonia [nTPM]":"7.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.2","Single Cell Type RNA - T-cells [nTPM]":"4.4","Single Cell Type RNA - Theca cells [nTPM]":"9.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.2","Single Cell Type RNA - Urothelial cells [nTPM]":"2.9"},{"Gene":"DBT","Gene synonym":["BCKAD-E2","BCKDH-E2","BCOADC-E2"],"Ensembl":"ENSG00000137992","Gene description":"Dihydrolipoamide branched chain transacylase E2","Uniprot":["P11182"],"Chromosome":"1","Position":"100186919-100249834","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant","Maple syrup urine disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"65.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026481","HPA026485","HPA026533"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA026481":"AB_1847504","HPA026485":"AB_1847505","HPA026533":"AB_1847506"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.79e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.1","Tissue RNA - adrenal gland [nTPM]":"13.6","Tissue RNA - amygdala [nTPM]":"4.4","Tissue RNA - appendix [nTPM]":"5.9","Tissue RNA - basal ganglia [nTPM]":"5.2","Tissue RNA - bone marrow [nTPM]":"4.6","Tissue RNA - breast [nTPM]":"11.8","Tissue RNA - cerebellum [nTPM]":"4.3","Tissue RNA - cerebral cortex [nTPM]":"4.9","Tissue RNA - cervix [nTPM]":"11.3","Tissue RNA - choroid plexus [nTPM]":"3.7","Tissue RNA - colon [nTPM]":"9.2","Tissue RNA - duodenum [nTPM]":"8.0","Tissue RNA - endometrium 1 [nTPM]":"8.2","Tissue RNA - epididymis [nTPM]":"6.0","Tissue RNA - esophagus [nTPM]":"12.8","Tissue RNA - fallopian tube [nTPM]":"11.1","Tissue RNA - gallbladder [nTPM]":"6.3","Tissue RNA - heart muscle [nTPM]":"25.9","Tissue RNA - hippocampal formation [nTPM]":"4.2","Tissue RNA - hypothalamus [nTPM]":"5.0","Tissue RNA - kidney [nTPM]":"30.3","Tissue RNA - liver [nTPM]":"43.4","Tissue RNA - lung [nTPM]":"7.4","Tissue RNA - lymph node [nTPM]":"7.5","Tissue RNA - medulla oblongata [nTPM]":"5.6","Tissue RNA - midbrain [nTPM]":"4.6","Tissue RNA - ovary [nTPM]":"11.1","Tissue RNA - pancreas [nTPM]":"15.4","Tissue RNA - parathyroid gland [nTPM]":"19.4","Tissue RNA - pituitary gland [nTPM]":"2.3","Tissue RNA - placenta [nTPM]":"10.0","Tissue RNA - pons [nTPM]":"4.5","Tissue RNA - prostate [nTPM]":"15.9","Tissue RNA - rectum [nTPM]":"10.2","Tissue RNA - retina [nTPM]":"5.9","Tissue RNA - salivary gland [nTPM]":"12.8","Tissue RNA - seminal vesicle [nTPM]":"11.2","Tissue RNA - skeletal muscle [nTPM]":"13.4","Tissue RNA - skin 1 [nTPM]":"7.4","Tissue RNA - small intestine [nTPM]":"7.1","Tissue RNA - smooth muscle [nTPM]":"8.0","Tissue RNA - spinal cord [nTPM]":"4.6","Tissue RNA - spleen [nTPM]":"6.1","Tissue RNA - stomach 1 [nTPM]":"17.3","Tissue RNA - testis [nTPM]":"4.7","Tissue RNA - thalamus [nTPM]":"5.2","Tissue RNA - thymus [nTPM]":"9.9","Tissue RNA - thyroid gland [nTPM]":"17.2","Tissue RNA - tongue [nTPM]":"19.2","Tissue RNA - tonsil [nTPM]":"8.9","Tissue RNA - urinary bladder [nTPM]":"9.4","Tissue RNA - vagina [nTPM]":"4.0","Tissue RNA - white matter [nTPM]":"7.1","Cell RNA - A-431 [nTPM]":"18.5","Cell RNA - A549 [nTPM]":"8.2","Cell RNA - AF22 [nTPM]":"9.5","Cell RNA - AN3-CA [nTPM]":"17.4","Cell RNA - ASC diff [nTPM]":"23.9","Cell RNA - ASC TERT1 [nTPM]":"17.6","Cell RNA - BEWO [nTPM]":"20.6","Cell RNA - BJ [nTPM]":"13.1","Cell RNA - BJ hTERT+ [nTPM]":"12.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.6","Cell RNA - CACO-2 [nTPM]":"17.7","Cell RNA - CAPAN-2 [nTPM]":"7.4","Cell RNA - Daudi [nTPM]":"17.1","Cell RNA - EFO-21 [nTPM]":"18.3","Cell RNA - fHDF\/TERT166 [nTPM]":"9.3","Cell RNA - GAMG [nTPM]":"8.1","Cell RNA - HaCaT [nTPM]":"18.7","Cell RNA - HAP1 [nTPM]":"20.3","Cell RNA - HBEC3-KT [nTPM]":"17.7","Cell RNA - HBF TERT88 [nTPM]":"16.8","Cell RNA - HDLM-2 [nTPM]":"18.2","Cell RNA - HEK 293 [nTPM]":"11.5","Cell RNA - HEL [nTPM]":"12.1","Cell RNA - HeLa [nTPM]":"16.3","Cell RNA - Hep G2 [nTPM]":"9.5","Cell RNA - HHSteC [nTPM]":"18.0","Cell RNA - HL-60 [nTPM]":"16.1","Cell RNA - HMC-1 [nTPM]":"6.1","Cell RNA - HSkMC [nTPM]":"18.2","Cell RNA - hTCEpi [nTPM]":"18.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.6","Cell RNA - hTERT-HME1 [nTPM]":"17.9","Cell RNA - hTERT-RPE1 [nTPM]":"11.4","Cell RNA - HUVEC TERT2 [nTPM]":"12.4","Cell RNA - JURKAT [nTPM]":"17.9","Cell RNA - K-562 [nTPM]":"20.9","Cell RNA - Karpas-707 [nTPM]":"19.2","Cell RNA - LHCN-M2 [nTPM]":"11.1","Cell RNA - MCF7 [nTPM]":"4.9","Cell RNA - MOLT-4 [nTPM]":"14.4","Cell RNA - NB-4 [nTPM]":"4.1","Cell RNA - NTERA-2 [nTPM]":"18.6","Cell RNA - OE19 [nTPM]":"14.8","Cell RNA - PC-3 [nTPM]":"18.4","Cell RNA - REH [nTPM]":"14.1","Cell RNA - RH-30 [nTPM]":"30.3","Cell RNA - RPMI-8226 [nTPM]":"14.2","Cell RNA - RPTEC TERT1 [nTPM]":"15.3","Cell RNA - RT4 [nTPM]":"15.9","Cell RNA - SCLC-21H [nTPM]":"15.8","Cell RNA - SH-SY5Y [nTPM]":"8.7","Cell RNA - SiHa [nTPM]":"27.5","Cell RNA - SK-BR-3 [nTPM]":"25.4","Cell RNA - SK-MEL-30 [nTPM]":"23.7","Cell RNA - SuSa [nTPM]":"16.7","Cell RNA - T-47d [nTPM]":"20.9","Cell RNA - THP-1 [nTPM]":"11.9","Cell RNA - TIME [nTPM]":"10.8","Cell RNA - U-138 MG [nTPM]":"12.1","Cell RNA - U-2 OS [nTPM]":"7.6","Cell RNA - U-2197 [nTPM]":"15.9","Cell RNA - U-251 MG [nTPM]":"11.0","Cell RNA - U-266\/70 [nTPM]":"12.7","Cell RNA - U-266\/84 [nTPM]":"14.1","Cell RNA - U-698 [nTPM]":"9.1","Cell RNA - U-87 MG [nTPM]":"13.8","Cell RNA - U-937 [nTPM]":"10.7","Cell RNA - WM-115 [nTPM]":"5.3","Blood RNA - basophil [nTPM]":"2.1","Blood RNA - classical monocyte [nTPM]":"1.2","Blood RNA - eosinophil [nTPM]":"0.8","Blood RNA - gdT-cell [nTPM]":"2.2","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"2.4","Blood RNA - memory B-cell [nTPM]":"1.9","Blood RNA - memory CD4 T-cell [nTPM]":"2.0","Blood RNA - memory CD8 T-cell [nTPM]":"1.9","Blood RNA - myeloid DC [nTPM]":"1.2","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"2.0","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"1.5","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"4.4","Brain RNA - basal ganglia [nTPM]":"5.2","Brain RNA - cerebellum [nTPM]":"4.3","Brain RNA - cerebral cortex [nTPM]":"4.9","Brain RNA - hippocampal formation [nTPM]":"4.2","Brain RNA - hypothalamus [nTPM]":"5.0","Brain RNA - medulla oblongata [nTPM]":"5.6","Brain RNA - midbrain [nTPM]":"4.6","Brain RNA - pons [nTPM]":"4.5","Brain RNA - spinal cord [nTPM]":"4.6","Brain RNA - thalamus [nTPM]":"5.2","Brain RNA - white matter [nTPM]":"7.1","Single Cell Type RNA - Adipocytes [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"36.4","Single Cell Type RNA - Astrocytes [nTPM]":"29.0","Single Cell Type RNA - B-cells [nTPM]":"9.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"22.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"65.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"11.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.8","Single Cell Type RNA - dendritic cells [nTPM]":"10.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"50.9","Single Cell Type RNA - Ductal cells [nTPM]":"10.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.5","Single Cell Type RNA - Endothelial cells [nTPM]":"11.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.1","Single Cell Type RNA - Erythroid cells [nTPM]":"8.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"24.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.6","Single Cell Type RNA - Fibroblasts [nTPM]":"11.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.4","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"19.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.4","Single Cell Type RNA - Hepatocytes [nTPM]":"53.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.7","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.0","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"8.8","Single Cell Type RNA - Langerhans cells [nTPM]":"5.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.7","Single Cell Type RNA - Leydig cells [nTPM]":"15.2","Single Cell Type RNA - Macrophages [nTPM]":"7.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"10.3","Single Cell Type RNA - Muller glia cells [nTPM]":"14.5","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"22.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"26.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.4","Single Cell Type RNA - Paneth cells [nTPM]":"6.0","Single Cell Type RNA - Peritubular cells [nTPM]":"21.1","Single Cell Type RNA - Plasma cells [nTPM]":"7.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"32.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"22.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.9","Single Cell Type RNA - Spermatocytes [nTPM]":"2.8","Single Cell Type RNA - Spermatogonia [nTPM]":"6.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.2","Single Cell Type RNA - T-cells [nTPM]":"9.7","Single Cell Type RNA - Theca cells [nTPM]":"17.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.1","Single Cell Type RNA - Urothelial cells [nTPM]":"5.5"},{"Gene":"DCPS","Gene synonym":["HINT-5","HINT5","HSL1","HSPC015"],"Ensembl":"ENSG00000110063","Gene description":"Decapping enzyme, scavenger","Uniprot":["Q96C86"],"Chromosome":"11","Position":"126304060-126350005","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"50.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"101.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"46.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"OE19":"79.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039632","HPA058597"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1200000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA039632":"AB_10794200","HPA058597":"AB_2683770"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.3","Tissue RNA - adrenal gland [nTPM]":"11.4","Tissue RNA - amygdala [nTPM]":"2.8","Tissue RNA - appendix [nTPM]":"7.4","Tissue RNA - basal ganglia [nTPM]":"4.0","Tissue RNA - bone marrow [nTPM]":"12.1","Tissue RNA - breast [nTPM]":"8.5","Tissue RNA - cerebellum [nTPM]":"5.0","Tissue RNA - cerebral cortex [nTPM]":"4.5","Tissue RNA - cervix [nTPM]":"10.9","Tissue RNA - choroid plexus [nTPM]":"8.1","Tissue RNA - colon [nTPM]":"10.1","Tissue RNA - duodenum [nTPM]":"4.7","Tissue RNA - endometrium 1 [nTPM]":"11.0","Tissue RNA - epididymis [nTPM]":"4.1","Tissue RNA - esophagus [nTPM]":"11.3","Tissue RNA - fallopian tube [nTPM]":"8.6","Tissue RNA - gallbladder [nTPM]":"16.0","Tissue RNA - heart muscle [nTPM]":"9.9","Tissue RNA - hippocampal formation [nTPM]":"3.9","Tissue RNA - hypothalamus [nTPM]":"3.2","Tissue RNA - kidney [nTPM]":"13.5","Tissue RNA - liver [nTPM]":"50.7","Tissue RNA - lung [nTPM]":"9.0","Tissue RNA - lymph node [nTPM]":"12.1","Tissue RNA - medulla oblongata [nTPM]":"3.3","Tissue RNA - midbrain [nTPM]":"3.4","Tissue RNA - ovary [nTPM]":"9.2","Tissue RNA - pancreas [nTPM]":"12.1","Tissue RNA - parathyroid gland [nTPM]":"3.5","Tissue RNA - pituitary gland [nTPM]":"8.2","Tissue RNA - placenta [nTPM]":"4.0","Tissue RNA - pons [nTPM]":"2.9","Tissue RNA - prostate [nTPM]":"8.1","Tissue RNA - rectum [nTPM]":"5.9","Tissue RNA - retina [nTPM]":"6.3","Tissue RNA - salivary gland [nTPM]":"12.0","Tissue RNA - seminal vesicle [nTPM]":"5.3","Tissue RNA - skeletal muscle [nTPM]":"14.6","Tissue RNA - skin 1 [nTPM]":"11.3","Tissue RNA - small intestine [nTPM]":"9.4","Tissue RNA - smooth muscle [nTPM]":"5.5","Tissue RNA - spinal cord [nTPM]":"2.7","Tissue RNA - spleen [nTPM]":"17.3","Tissue RNA - stomach 1 [nTPM]":"8.7","Tissue RNA - testis [nTPM]":"6.1","Tissue RNA - thalamus [nTPM]":"3.6","Tissue RNA - thymus [nTPM]":"8.9","Tissue RNA - thyroid gland [nTPM]":"7.5","Tissue RNA - tongue [nTPM]":"5.8","Tissue RNA - tonsil [nTPM]":"9.6","Tissue RNA - urinary bladder [nTPM]":"13.3","Tissue RNA - vagina [nTPM]":"9.2","Tissue RNA - white matter [nTPM]":"3.4","Cell RNA - A-431 [nTPM]":"13.9","Cell RNA - A549 [nTPM]":"8.5","Cell RNA - AF22 [nTPM]":"10.2","Cell RNA - AN3-CA [nTPM]":"19.8","Cell RNA - ASC diff [nTPM]":"7.9","Cell RNA - ASC TERT1 [nTPM]":"11.2","Cell RNA - BEWO [nTPM]":"8.9","Cell RNA - BJ [nTPM]":"6.5","Cell RNA - BJ hTERT+ [nTPM]":"10.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.8","Cell RNA - CACO-2 [nTPM]":"17.5","Cell RNA - CAPAN-2 [nTPM]":"29.1","Cell RNA - Daudi [nTPM]":"19.5","Cell RNA - EFO-21 [nTPM]":"28.0","Cell RNA - fHDF\/TERT166 [nTPM]":"12.2","Cell RNA - GAMG [nTPM]":"7.5","Cell RNA - HaCaT [nTPM]":"16.2","Cell RNA - HAP1 [nTPM]":"14.4","Cell RNA - HBEC3-KT [nTPM]":"24.4","Cell RNA - HBF TERT88 [nTPM]":"5.9","Cell RNA - HDLM-2 [nTPM]":"35.8","Cell RNA - HEK 293 [nTPM]":"7.1","Cell RNA - HEL [nTPM]":"27.1","Cell RNA - HeLa [nTPM]":"9.9","Cell RNA - Hep G2 [nTPM]":"14.7","Cell RNA - HHSteC [nTPM]":"18.8","Cell RNA - HL-60 [nTPM]":"33.3","Cell RNA - HMC-1 [nTPM]":"25.4","Cell RNA - HSkMC [nTPM]":"12.5","Cell RNA - hTCEpi [nTPM]":"14.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.0","Cell RNA - hTERT-HME1 [nTPM]":"17.6","Cell RNA - hTERT-RPE1 [nTPM]":"5.9","Cell RNA - HUVEC TERT2 [nTPM]":"14.1","Cell RNA - JURKAT [nTPM]":"17.0","Cell RNA - K-562 [nTPM]":"11.6","Cell RNA - Karpas-707 [nTPM]":"34.8","Cell RNA - LHCN-M2 [nTPM]":"11.2","Cell RNA - MCF7 [nTPM]":"21.6","Cell RNA - MOLT-4 [nTPM]":"21.1","Cell RNA - NB-4 [nTPM]":"41.5","Cell RNA - NTERA-2 [nTPM]":"8.0","Cell RNA - OE19 [nTPM]":"79.8","Cell RNA - PC-3 [nTPM]":"28.7","Cell RNA - REH [nTPM]":"13.7","Cell RNA - RH-30 [nTPM]":"13.8","Cell RNA - RPMI-8226 [nTPM]":"40.6","Cell RNA - RPTEC TERT1 [nTPM]":"11.4","Cell RNA - RT4 [nTPM]":"15.1","Cell RNA - SCLC-21H [nTPM]":"16.1","Cell RNA - SH-SY5Y [nTPM]":"11.0","Cell RNA - SiHa [nTPM]":"20.3","Cell RNA - SK-BR-3 [nTPM]":"21.1","Cell RNA - SK-MEL-30 [nTPM]":"15.8","Cell RNA - SuSa [nTPM]":"6.3","Cell RNA - T-47d [nTPM]":"33.8","Cell RNA - THP-1 [nTPM]":"22.1","Cell RNA - TIME [nTPM]":"9.3","Cell RNA - U-138 MG [nTPM]":"18.7","Cell RNA - U-2 OS [nTPM]":"7.3","Cell RNA - U-2197 [nTPM]":"8.9","Cell RNA - U-251 MG [nTPM]":"13.7","Cell RNA - U-266\/70 [nTPM]":"13.4","Cell RNA - U-266\/84 [nTPM]":"14.6","Cell RNA - U-698 [nTPM]":"20.0","Cell RNA - U-87 MG [nTPM]":"6.0","Cell RNA - U-937 [nTPM]":"51.0","Cell RNA - WM-115 [nTPM]":"46.7","Blood RNA - basophil [nTPM]":"4.2","Blood RNA - classical monocyte [nTPM]":"10.5","Blood RNA - eosinophil [nTPM]":"4.3","Blood RNA - gdT-cell [nTPM]":"9.3","Blood RNA - intermediate monocyte [nTPM]":"15.2","Blood RNA - MAIT T-cell [nTPM]":"7.8","Blood RNA - memory B-cell [nTPM]":"13.0","Blood RNA - memory CD4 T-cell [nTPM]":"8.5","Blood RNA - memory CD8 T-cell [nTPM]":"9.7","Blood RNA - myeloid DC [nTPM]":"16.6","Blood RNA - naive B-cell [nTPM]":"8.6","Blood RNA - naive CD4 T-cell [nTPM]":"6.4","Blood RNA - naive CD8 T-cell [nTPM]":"6.7","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"8.9","Blood RNA - non-classical monocyte [nTPM]":"15.3","Blood RNA - plasmacytoid DC [nTPM]":"46.6","Blood RNA - T-reg [nTPM]":"15.4","Blood RNA - total PBMC [nTPM]":"8.9","Brain RNA - amygdala [nTPM]":"2.8","Brain RNA - basal ganglia [nTPM]":"4.0","Brain RNA - cerebellum [nTPM]":"5.0","Brain RNA - cerebral cortex [nTPM]":"4.5","Brain RNA - hippocampal formation [nTPM]":"3.9","Brain RNA - hypothalamus [nTPM]":"3.2","Brain RNA - medulla oblongata [nTPM]":"3.3","Brain RNA - midbrain [nTPM]":"3.4","Brain RNA - pons [nTPM]":"2.9","Brain RNA - spinal cord [nTPM]":"2.7","Brain RNA - thalamus [nTPM]":"3.6","Brain RNA - white matter [nTPM]":"3.4","Single Cell Type RNA - Adipocytes [nTPM]":"14.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.2","Single Cell Type RNA - Astrocytes [nTPM]":"6.2","Single Cell Type RNA - B-cells [nTPM]":"31.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"38.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"6.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"47.1","Single Cell Type RNA - Club cells [nTPM]":"18.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"42.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"39.9","Single Cell Type RNA - dendritic cells [nTPM]":"35.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"56.7","Single Cell Type RNA - Ductal cells [nTPM]":"19.7","Single Cell Type RNA - Early spermatids [nTPM]":"8.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.1","Single Cell Type RNA - Endothelial cells [nTPM]":"12.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.3","Single Cell Type RNA - Erythroid cells [nTPM]":"14.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"29.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"43.8","Single Cell Type RNA - Fibroblasts [nTPM]":"15.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"23.2","Single Cell Type RNA - granulocytes [nTPM]":"17.1","Single Cell Type RNA - Granulosa cells [nTPM]":"9.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.6","Single Cell Type RNA - Hepatocytes [nTPM]":"31.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"29.2","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.0","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"14.1","Single Cell Type RNA - Langerhans cells [nTPM]":"11.7","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"17.1","Single Cell Type RNA - Macrophages [nTPM]":"16.8","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"15.3","Single Cell Type RNA - Muller glia cells [nTPM]":"10.1","Single Cell Type RNA - NK-cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.1","Single Cell Type RNA - Paneth cells [nTPM]":"14.9","Single Cell Type RNA - Peritubular cells [nTPM]":"18.4","Single Cell Type RNA - Plasma cells [nTPM]":"101.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.4","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.6","Single Cell Type RNA - Spermatocytes [nTPM]":"14.8","Single Cell Type RNA - Spermatogonia [nTPM]":"24.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"27.1","Single Cell Type RNA - T-cells [nTPM]":"24.3","Single Cell Type RNA - Theca cells [nTPM]":"16.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.4","Single Cell Type RNA - Urothelial cells [nTPM]":"24.0"},{"Gene":"DCXR","Gene synonym":["DCR","HCR2","KIDCR","P34H","SDR20C1"],"Ensembl":"ENSG00000169738","Gene description":"Dicarbonyl and L-xylulose reductase","Uniprot":["Q7Z4W1"],"Chromosome":"17","Position":"82035136-82037709","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism","Glucose metabolism","Xylose metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"liver":"1851.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"812.0","Hepatocytes":"3510.3","Proximal tubular cells":"2919.4"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"liver cancer":"305.9","prostate cancer":"163.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"365.2","MCF7":"446.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023371","HPA023863"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoli","Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4000000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Nucleoli","Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA023371":"AB_1847530","HPA023863":"AB_1847531"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.70e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.13e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Tissue RNA - adipose tissue [nTPM]":"106.7","Tissue RNA - adrenal gland [nTPM]":"43.9","Tissue RNA - amygdala [nTPM]":"93.1","Tissue RNA - appendix [nTPM]":"15.2","Tissue RNA - basal ganglia [nTPM]":"95.3","Tissue RNA - bone marrow [nTPM]":"25.3","Tissue RNA - breast [nTPM]":"107.6","Tissue RNA - cerebellum [nTPM]":"102.5","Tissue RNA - cerebral cortex [nTPM]":"111.1","Tissue RNA - cervix [nTPM]":"52.0","Tissue RNA - choroid plexus [nTPM]":"84.4","Tissue RNA - colon [nTPM]":"49.6","Tissue RNA - duodenum [nTPM]":"29.2","Tissue RNA - endometrium 1 [nTPM]":"39.5","Tissue RNA - epididymis [nTPM]":"281.3","Tissue RNA - esophagus [nTPM]":"96.6","Tissue RNA - fallopian tube [nTPM]":"59.2","Tissue RNA - gallbladder [nTPM]":"10.8","Tissue RNA - heart muscle [nTPM]":"132.7","Tissue RNA - hippocampal formation [nTPM]":"87.6","Tissue RNA - hypothalamus [nTPM]":"100.7","Tissue RNA - kidney [nTPM]":"239.9","Tissue RNA - liver [nTPM]":"1851.6","Tissue RNA - lung [nTPM]":"61.0","Tissue RNA - lymph node [nTPM]":"16.6","Tissue RNA - medulla oblongata [nTPM]":"102.4","Tissue RNA - midbrain [nTPM]":"98.0","Tissue RNA - ovary [nTPM]":"70.0","Tissue RNA - pancreas [nTPM]":"71.6","Tissue RNA - parathyroid gland [nTPM]":"46.1","Tissue RNA - pituitary gland [nTPM]":"63.9","Tissue RNA - placenta [nTPM]":"20.2","Tissue RNA - pons [nTPM]":"105.9","Tissue RNA - prostate [nTPM]":"138.0","Tissue RNA - rectum [nTPM]":"20.9","Tissue RNA - retina [nTPM]":"9.7","Tissue RNA - salivary gland [nTPM]":"103.4","Tissue RNA - seminal vesicle [nTPM]":"33.6","Tissue RNA - skeletal muscle [nTPM]":"187.3","Tissue RNA - skin 1 [nTPM]":"87.6","Tissue RNA - small intestine [nTPM]":"44.4","Tissue RNA - smooth muscle [nTPM]":"10.4","Tissue RNA - spinal cord [nTPM]":"91.8","Tissue RNA - spleen [nTPM]":"35.8","Tissue RNA - stomach 1 [nTPM]":"167.0","Tissue RNA - testis [nTPM]":"44.8","Tissue RNA - thalamus [nTPM]":"105.9","Tissue RNA - thymus [nTPM]":"26.1","Tissue RNA - thyroid gland [nTPM]":"60.7","Tissue RNA - tongue [nTPM]":"80.6","Tissue RNA - tonsil [nTPM]":"19.6","Tissue RNA - urinary bladder [nTPM]":"48.9","Tissue RNA - vagina [nTPM]":"62.1","Tissue RNA - white matter [nTPM]":"94.9","Cell RNA - A-431 [nTPM]":"50.3","Cell RNA - A549 [nTPM]":"68.2","Cell RNA - AF22 [nTPM]":"32.8","Cell RNA - AN3-CA [nTPM]":"56.4","Cell RNA - ASC diff [nTPM]":"123.2","Cell RNA - ASC TERT1 [nTPM]":"31.8","Cell RNA - BEWO [nTPM]":"80.4","Cell RNA - BJ [nTPM]":"25.0","Cell RNA - BJ hTERT+ [nTPM]":"33.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"68.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"48.4","Cell RNA - CACO-2 [nTPM]":"122.0","Cell RNA - CAPAN-2 [nTPM]":"21.3","Cell RNA - Daudi [nTPM]":"100.3","Cell RNA - EFO-21 [nTPM]":"47.4","Cell RNA - fHDF\/TERT166 [nTPM]":"35.9","Cell RNA - GAMG [nTPM]":"9.4","Cell RNA - HaCaT [nTPM]":"57.4","Cell RNA - HAP1 [nTPM]":"59.6","Cell RNA - HBEC3-KT [nTPM]":"52.6","Cell RNA - HBF TERT88 [nTPM]":"24.1","Cell RNA - HDLM-2 [nTPM]":"21.4","Cell RNA - HEK 293 [nTPM]":"145.9","Cell RNA - HEL [nTPM]":"96.9","Cell RNA - HeLa [nTPM]":"48.8","Cell RNA - Hep G2 [nTPM]":"365.2","Cell RNA - HHSteC [nTPM]":"143.2","Cell RNA - HL-60 [nTPM]":"75.6","Cell RNA - HMC-1 [nTPM]":"114.5","Cell RNA - HSkMC [nTPM]":"44.6","Cell RNA - hTCEpi [nTPM]":"62.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.7","Cell RNA - hTERT-HME1 [nTPM]":"79.8","Cell RNA - hTERT-RPE1 [nTPM]":"16.0","Cell RNA - HUVEC TERT2 [nTPM]":"41.1","Cell RNA - JURKAT [nTPM]":"61.1","Cell RNA - K-562 [nTPM]":"112.4","Cell RNA - Karpas-707 [nTPM]":"76.3","Cell RNA - LHCN-M2 [nTPM]":"36.5","Cell RNA - MCF7 [nTPM]":"446.2","Cell RNA - MOLT-4 [nTPM]":"63.7","Cell RNA - NB-4 [nTPM]":"184.1","Cell RNA - NTERA-2 [nTPM]":"35.0","Cell RNA - OE19 [nTPM]":"242.9","Cell RNA - PC-3 [nTPM]":"71.3","Cell RNA - REH [nTPM]":"57.9","Cell RNA - RH-30 [nTPM]":"42.0","Cell RNA - RPMI-8226 [nTPM]":"135.3","Cell RNA - RPTEC TERT1 [nTPM]":"53.3","Cell RNA - RT4 [nTPM]":"71.9","Cell RNA - SCLC-21H [nTPM]":"85.5","Cell RNA - SH-SY5Y [nTPM]":"51.0","Cell RNA - SiHa [nTPM]":"35.5","Cell RNA - SK-BR-3 [nTPM]":"287.5","Cell RNA - SK-MEL-30 [nTPM]":"46.0","Cell RNA - SuSa [nTPM]":"19.7","Cell RNA - T-47d [nTPM]":"213.4","Cell RNA - THP-1 [nTPM]":"74.5","Cell RNA - TIME [nTPM]":"20.5","Cell RNA - U-138 MG [nTPM]":"36.6","Cell RNA - U-2 OS [nTPM]":"45.0","Cell RNA - U-2197 [nTPM]":"48.9","Cell RNA - U-251 MG [nTPM]":"48.2","Cell RNA - U-266\/70 [nTPM]":"73.7","Cell RNA - U-266\/84 [nTPM]":"56.2","Cell RNA - U-698 [nTPM]":"50.2","Cell RNA - U-87 MG [nTPM]":"31.4","Cell RNA - U-937 [nTPM]":"83.0","Cell RNA - WM-115 [nTPM]":"26.7","Blood RNA - basophil [nTPM]":"49.5","Blood RNA - classical monocyte [nTPM]":"92.6","Blood RNA - eosinophil [nTPM]":"77.9","Blood RNA - gdT-cell [nTPM]":"66.5","Blood RNA - intermediate monocyte [nTPM]":"92.0","Blood RNA - MAIT T-cell [nTPM]":"64.1","Blood RNA - memory B-cell [nTPM]":"86.8","Blood RNA - memory CD4 T-cell [nTPM]":"83.0","Blood RNA - memory CD8 T-cell [nTPM]":"64.7","Blood RNA - myeloid DC [nTPM]":"151.3","Blood RNA - naive B-cell [nTPM]":"99.2","Blood RNA - naive CD4 T-cell [nTPM]":"117.7","Blood RNA - naive CD8 T-cell [nTPM]":"85.4","Blood RNA - neutrophil [nTPM]":"47.2","Blood RNA - NK-cell [nTPM]":"108.9","Blood RNA - non-classical monocyte [nTPM]":"88.1","Blood RNA - plasmacytoid DC [nTPM]":"121.6","Blood RNA - T-reg [nTPM]":"98.9","Blood RNA - total PBMC [nTPM]":"110.1","Brain RNA - amygdala [nTPM]":"93.1","Brain RNA - basal ganglia [nTPM]":"95.3","Brain RNA - cerebellum [nTPM]":"102.5","Brain RNA - cerebral cortex [nTPM]":"111.1","Brain RNA - hippocampal formation [nTPM]":"87.6","Brain RNA - hypothalamus [nTPM]":"100.7","Brain RNA - medulla oblongata [nTPM]":"102.4","Brain RNA - midbrain [nTPM]":"98.0","Brain RNA - pons [nTPM]":"105.9","Brain RNA - spinal cord [nTPM]":"91.8","Brain RNA - thalamus [nTPM]":"105.9","Brain RNA - white matter [nTPM]":"94.9","Single Cell Type RNA - Adipocytes [nTPM]":"29.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"198.2","Single Cell Type RNA - Astrocytes [nTPM]":"16.6","Single Cell Type RNA - B-cells [nTPM]":"133.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"58.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"200.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"113.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"109.8","Single Cell Type RNA - Bipolar cells [nTPM]":"16.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"301.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"269.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"120.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"183.0","Single Cell Type RNA - Club cells [nTPM]":"123.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"178.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"372.1","Single Cell Type RNA - dendritic cells [nTPM]":"116.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"152.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"812.0","Single Cell Type RNA - Ductal cells [nTPM]":"41.4","Single Cell Type RNA - Early spermatids [nTPM]":"6.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"67.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"50.9","Single Cell Type RNA - Endothelial cells [nTPM]":"44.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"54.7","Single Cell Type RNA - Erythroid cells [nTPM]":"335.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"42.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"450.6","Single Cell Type RNA - Fibroblasts [nTPM]":"65.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"151.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"102.3","Single Cell Type RNA - granulocytes [nTPM]":"64.7","Single Cell Type RNA - Granulosa cells [nTPM]":"62.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"138.5","Single Cell Type RNA - Hepatocytes [nTPM]":"3510.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"164.7","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"170.4","Single Cell Type RNA - Ionocytes [nTPM]":"189.2","Single Cell Type RNA - Kupffer cells [nTPM]":"165.7","Single Cell Type RNA - Langerhans cells [nTPM]":"65.6","Single Cell Type RNA - Late spermatids [nTPM]":"22.6","Single Cell Type RNA - Leydig cells [nTPM]":"70.8","Single Cell Type RNA - Macrophages [nTPM]":"82.3","Single Cell Type RNA - Melanocytes [nTPM]":"179.7","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"52.8","Single Cell Type RNA - Muller glia cells [nTPM]":"145.1","Single Cell Type RNA - NK-cells [nTPM]":"78.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"30.4","Single Cell Type RNA - Paneth cells [nTPM]":"135.7","Single Cell Type RNA - Peritubular cells [nTPM]":"47.4","Single Cell Type RNA - Plasma cells [nTPM]":"98.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"215.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"158.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2919.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"55.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"26.5","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"40.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"79.6","Single Cell Type RNA - Spermatocytes [nTPM]":"10.3","Single Cell Type RNA - Spermatogonia [nTPM]":"48.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"219.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"73.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"342.6","Single Cell Type RNA - T-cells [nTPM]":"135.7","Single Cell Type RNA - Theca cells [nTPM]":"118.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"154.6","Single Cell Type RNA - Urothelial cells [nTPM]":"178.8"},{"Gene":"DDOST","Gene synonym":["GATD6","KIAA0115","OST","OST48","WBP1"],"Ensembl":"ENSG00000244038","Gene description":"Dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit","Uniprot":["P39656"],"Chromosome":"1","Position":"20651767-20661544","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"350.7","Syncytiotrophoblasts":"349.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009746","HPA046841","HPA052867"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"120000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB009746":"AB_2092075","HPA046841":"AB_2679834","HPA052867":"AB_2681977"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.99e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.88e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.64e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.05e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Tissue RNA - adipose tissue [nTPM]":"98.1","Tissue RNA - adrenal gland [nTPM]":"132.7","Tissue RNA - amygdala [nTPM]":"44.6","Tissue RNA - appendix [nTPM]":"108.5","Tissue RNA - basal ganglia [nTPM]":"46.4","Tissue RNA - bone marrow [nTPM]":"191.4","Tissue RNA - breast [nTPM]":"111.9","Tissue RNA - cerebellum [nTPM]":"44.9","Tissue RNA - cerebral cortex [nTPM]":"46.3","Tissue RNA - cervix [nTPM]":"130.7","Tissue RNA - choroid plexus [nTPM]":"64.1","Tissue RNA - colon [nTPM]":"161.4","Tissue RNA - duodenum [nTPM]":"119.4","Tissue RNA - endometrium 1 [nTPM]":"115.8","Tissue RNA - epididymis [nTPM]":"224.5","Tissue RNA - esophagus [nTPM]":"113.2","Tissue RNA - fallopian tube [nTPM]":"137.4","Tissue RNA - gallbladder [nTPM]":"98.2","Tissue RNA - heart muscle [nTPM]":"123.4","Tissue RNA - hippocampal formation [nTPM]":"47.2","Tissue RNA - hypothalamus [nTPM]":"53.7","Tissue RNA - kidney [nTPM]":"100.6","Tissue RNA - liver [nTPM]":"137.2","Tissue RNA - lung [nTPM]":"104.4","Tissue RNA - lymph node [nTPM]":"104.6","Tissue RNA - medulla oblongata [nTPM]":"48.1","Tissue RNA - midbrain [nTPM]":"45.3","Tissue RNA - ovary [nTPM]":"139.5","Tissue RNA - pancreas [nTPM]":"259.8","Tissue RNA - parathyroid gland [nTPM]":"112.7","Tissue RNA - pituitary gland [nTPM]":"119.1","Tissue RNA - placenta [nTPM]":"183.3","Tissue RNA - pons [nTPM]":"46.9","Tissue RNA - prostate [nTPM]":"99.8","Tissue RNA - rectum [nTPM]":"165.7","Tissue RNA - retina [nTPM]":"42.1","Tissue RNA - salivary gland [nTPM]":"151.7","Tissue RNA - seminal vesicle [nTPM]":"130.4","Tissue RNA - skeletal muscle [nTPM]":"80.0","Tissue RNA - skin 1 [nTPM]":"87.3","Tissue RNA - small intestine [nTPM]":"108.4","Tissue RNA - smooth muscle [nTPM]":"122.8","Tissue RNA - spinal cord [nTPM]":"46.1","Tissue RNA - spleen [nTPM]":"113.1","Tissue RNA - stomach 1 [nTPM]":"139.0","Tissue RNA - testis [nTPM]":"83.4","Tissue RNA - thalamus [nTPM]":"52.4","Tissue RNA - thymus [nTPM]":"84.0","Tissue RNA - thyroid gland [nTPM]":"185.6","Tissue RNA - tongue [nTPM]":"66.4","Tissue RNA - tonsil [nTPM]":"121.6","Tissue RNA - urinary bladder [nTPM]":"119.3","Tissue RNA - vagina [nTPM]":"92.8","Tissue RNA - white matter [nTPM]":"51.4","Cell RNA - A-431 [nTPM]":"366.0","Cell RNA - A549 [nTPM]":"206.7","Cell RNA - AF22 [nTPM]":"178.8","Cell RNA - AN3-CA [nTPM]":"533.9","Cell RNA - ASC diff [nTPM]":"347.4","Cell RNA - ASC TERT1 [nTPM]":"359.8","Cell RNA - BEWO [nTPM]":"376.6","Cell RNA - BJ [nTPM]":"286.1","Cell RNA - BJ hTERT+ [nTPM]":"545.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"435.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"445.3","Cell RNA - CACO-2 [nTPM]":"278.9","Cell RNA - CAPAN-2 [nTPM]":"678.8","Cell RNA - Daudi [nTPM]":"275.8","Cell RNA - EFO-21 [nTPM]":"501.8","Cell RNA - fHDF\/TERT166 [nTPM]":"447.0","Cell RNA - GAMG [nTPM]":"238.7","Cell RNA - HaCaT [nTPM]":"292.7","Cell RNA - HAP1 [nTPM]":"250.4","Cell RNA - HBEC3-KT [nTPM]":"334.3","Cell RNA - HBF TERT88 [nTPM]":"321.3","Cell RNA - HDLM-2 [nTPM]":"257.0","Cell RNA - HEK 293 [nTPM]":"256.3","Cell RNA - HEL [nTPM]":"235.7","Cell RNA - HeLa [nTPM]":"138.5","Cell RNA - Hep G2 [nTPM]":"375.0","Cell RNA - HHSteC [nTPM]":"513.2","Cell RNA - HL-60 [nTPM]":"377.5","Cell RNA - HMC-1 [nTPM]":"618.8","Cell RNA - HSkMC [nTPM]":"371.6","Cell RNA - hTCEpi [nTPM]":"370.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"365.2","Cell RNA - hTERT-HME1 [nTPM]":"439.5","Cell RNA - hTERT-RPE1 [nTPM]":"522.8","Cell RNA - HUVEC TERT2 [nTPM]":"504.1","Cell RNA - JURKAT [nTPM]":"180.5","Cell RNA - K-562 [nTPM]":"116.3","Cell RNA - Karpas-707 [nTPM]":"445.0","Cell RNA - LHCN-M2 [nTPM]":"266.5","Cell RNA - MCF7 [nTPM]":"251.1","Cell RNA - MOLT-4 [nTPM]":"179.6","Cell RNA - NB-4 [nTPM]":"308.2","Cell RNA - NTERA-2 [nTPM]":"196.5","Cell RNA - OE19 [nTPM]":"529.8","Cell RNA - PC-3 [nTPM]":"214.2","Cell RNA - REH [nTPM]":"164.5","Cell RNA - RH-30 [nTPM]":"238.6","Cell RNA - RPMI-8226 [nTPM]":"492.2","Cell RNA - RPTEC TERT1 [nTPM]":"358.7","Cell RNA - RT4 [nTPM]":"150.4","Cell RNA - SCLC-21H [nTPM]":"133.0","Cell RNA - SH-SY5Y [nTPM]":"238.3","Cell RNA - SiHa [nTPM]":"294.0","Cell RNA - SK-BR-3 [nTPM]":"299.1","Cell RNA - SK-MEL-30 [nTPM]":"413.5","Cell RNA - SuSa [nTPM]":"257.1","Cell RNA - T-47d [nTPM]":"237.8","Cell RNA - THP-1 [nTPM]":"566.8","Cell RNA - TIME [nTPM]":"260.2","Cell RNA - U-138 MG [nTPM]":"249.7","Cell RNA - U-2 OS [nTPM]":"279.6","Cell RNA - U-2197 [nTPM]":"435.1","Cell RNA - U-251 MG [nTPM]":"274.6","Cell RNA - U-266\/70 [nTPM]":"586.1","Cell RNA - U-266\/84 [nTPM]":"677.5","Cell RNA - U-698 [nTPM]":"195.6","Cell RNA - U-87 MG [nTPM]":"409.4","Cell RNA - U-937 [nTPM]":"489.4","Cell RNA - WM-115 [nTPM]":"342.0","Blood RNA - basophil [nTPM]":"272.0","Blood RNA - classical monocyte [nTPM]":"268.3","Blood RNA - eosinophil [nTPM]":"257.3","Blood RNA - gdT-cell [nTPM]":"255.6","Blood RNA - intermediate monocyte [nTPM]":"284.2","Blood RNA - MAIT T-cell [nTPM]":"270.3","Blood RNA - memory B-cell [nTPM]":"230.4","Blood RNA - memory CD4 T-cell [nTPM]":"218.1","Blood RNA - memory CD8 T-cell [nTPM]":"239.9","Blood RNA - myeloid DC [nTPM]":"389.7","Blood RNA - naive B-cell [nTPM]":"207.8","Blood RNA - naive CD4 T-cell [nTPM]":"203.1","Blood RNA - naive CD8 T-cell [nTPM]":"209.6","Blood RNA - neutrophil [nTPM]":"63.8","Blood RNA - NK-cell [nTPM]":"266.1","Blood RNA - non-classical monocyte [nTPM]":"251.4","Blood RNA - plasmacytoid DC [nTPM]":"320.1","Blood RNA - T-reg [nTPM]":"256.0","Blood RNA - total PBMC [nTPM]":"490.6","Brain RNA - amygdala [nTPM]":"44.6","Brain RNA - basal ganglia [nTPM]":"46.4","Brain RNA - cerebellum [nTPM]":"44.9","Brain RNA - cerebral cortex [nTPM]":"46.3","Brain RNA - hippocampal formation [nTPM]":"47.2","Brain RNA - hypothalamus [nTPM]":"53.7","Brain RNA - medulla oblongata [nTPM]":"48.1","Brain RNA - midbrain [nTPM]":"45.3","Brain RNA - pons [nTPM]":"46.9","Brain RNA - spinal cord [nTPM]":"46.1","Brain RNA - thalamus [nTPM]":"52.4","Brain RNA - white matter [nTPM]":"51.4","Single Cell Type RNA - Adipocytes [nTPM]":"62.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"72.3","Single Cell Type RNA - Astrocytes [nTPM]":"7.5","Single Cell Type RNA - B-cells [nTPM]":"93.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"50.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"95.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"200.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"47.3","Single Cell Type RNA - Bipolar cells [nTPM]":"18.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"70.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"62.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"22.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"77.2","Single Cell Type RNA - Club cells [nTPM]":"120.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"35.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"350.7","Single Cell Type RNA - dendritic cells [nTPM]":"92.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"52.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"39.2","Single Cell Type RNA - Ductal cells [nTPM]":"162.5","Single Cell Type RNA - Early spermatids [nTPM]":"29.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"44.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"71.9","Single Cell Type RNA - Endothelial cells [nTPM]":"65.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"71.8","Single Cell Type RNA - Erythroid cells [nTPM]":"49.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"148.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"270.0","Single Cell Type RNA - Fibroblasts [nTPM]":"102.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"74.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"71.6","Single Cell Type RNA - granulocytes [nTPM]":"79.1","Single Cell Type RNA - Granulosa cells [nTPM]":"113.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"55.3","Single Cell Type RNA - Hepatocytes [nTPM]":"74.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"140.8","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"152.6","Single Cell Type RNA - Ionocytes [nTPM]":"79.3","Single Cell Type RNA - Kupffer cells [nTPM]":"66.8","Single Cell Type RNA - Langerhans cells [nTPM]":"78.8","Single Cell Type RNA - Late spermatids [nTPM]":"13.9","Single Cell Type RNA - Leydig cells [nTPM]":"74.6","Single Cell Type RNA - Macrophages [nTPM]":"74.5","Single Cell Type RNA - Melanocytes [nTPM]":"85.4","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"96.4","Single Cell Type RNA - Muller glia cells [nTPM]":"54.1","Single Cell Type RNA - NK-cells [nTPM]":"87.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"93.5","Single Cell Type RNA - Paneth cells [nTPM]":"89.7","Single Cell Type RNA - Peritubular cells [nTPM]":"60.9","Single Cell Type RNA - Plasma cells [nTPM]":"320.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"68.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"69.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"54.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"78.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.6","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"42.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"103.3","Single Cell Type RNA - Spermatocytes [nTPM]":"136.0","Single Cell Type RNA - Spermatogonia [nTPM]":"171.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"55.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"53.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"349.7","Single Cell Type RNA - T-cells [nTPM]":"78.5","Single Cell Type RNA - Theca cells [nTPM]":"122.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"133.7","Single Cell Type RNA - Urothelial cells [nTPM]":"84.3"},{"Gene":"DDX11","Gene synonym":["CHL1","CHLR1","KRG2","WABS"],"Ensembl":"ENSG00000013573","Gene description":"DEAD\/H-box helicase 11","Uniprot":["Q96FC9"],"Chromosome":"12","Position":"31073860-31104799","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","DNA replication","Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","DNA-binding","Helicase","Hydrolase","RNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"25.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065197"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA065197":"AB_2685430"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.40e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.23e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-3"},"Tissue RNA - adipose tissue [nTPM]":"5.9","Tissue RNA - adrenal gland [nTPM]":"6.4","Tissue RNA - amygdala [nTPM]":"6.0","Tissue RNA - appendix [nTPM]":"10.2","Tissue RNA - basal ganglia [nTPM]":"6.8","Tissue RNA - bone marrow [nTPM]":"29.2","Tissue RNA - breast [nTPM]":"7.2","Tissue RNA - cerebellum [nTPM]":"6.9","Tissue RNA - cerebral cortex [nTPM]":"7.3","Tissue RNA - cervix [nTPM]":"10.7","Tissue RNA - choroid plexus [nTPM]":"7.1","Tissue RNA - colon [nTPM]":"9.6","Tissue RNA - duodenum [nTPM]":"8.0","Tissue RNA - endometrium 1 [nTPM]":"7.5","Tissue RNA - epididymis [nTPM]":"4.3","Tissue RNA - esophagus [nTPM]":"9.5","Tissue RNA - fallopian tube [nTPM]":"8.0","Tissue RNA - gallbladder [nTPM]":"5.9","Tissue RNA - heart muscle [nTPM]":"5.3","Tissue RNA - hippocampal formation [nTPM]":"6.0","Tissue RNA - hypothalamus [nTPM]":"6.1","Tissue RNA - kidney [nTPM]":"9.2","Tissue RNA - liver [nTPM]":"9.3","Tissue RNA - lung [nTPM]":"6.1","Tissue RNA - lymph node [nTPM]":"13.2","Tissue RNA - medulla oblongata [nTPM]":"6.9","Tissue RNA - midbrain [nTPM]":"6.4","Tissue RNA - ovary [nTPM]":"11.0","Tissue RNA - pancreas [nTPM]":"17.5","Tissue RNA - parathyroid gland [nTPM]":"5.8","Tissue RNA - pituitary gland [nTPM]":"9.4","Tissue RNA - placenta [nTPM]":"5.4","Tissue RNA - pons [nTPM]":"6.9","Tissue RNA - prostate [nTPM]":"10.0","Tissue RNA - rectum [nTPM]":"10.1","Tissue RNA - retina [nTPM]":"6.6","Tissue RNA - salivary gland [nTPM]":"8.6","Tissue RNA - seminal vesicle [nTPM]":"5.3","Tissue RNA - skeletal muscle [nTPM]":"10.6","Tissue RNA - skin 1 [nTPM]":"16.7","Tissue RNA - small intestine [nTPM]":"13.4","Tissue RNA - smooth muscle [nTPM]":"3.6","Tissue RNA - spinal cord [nTPM]":"6.1","Tissue RNA - spleen [nTPM]":"13.8","Tissue RNA - stomach 1 [nTPM]":"9.6","Tissue RNA - testis [nTPM]":"8.8","Tissue RNA - thalamus [nTPM]":"6.7","Tissue RNA - thymus [nTPM]":"24.0","Tissue RNA - thyroid gland [nTPM]":"8.0","Tissue RNA - tongue [nTPM]":"6.6","Tissue RNA - tonsil [nTPM]":"11.1","Tissue RNA - urinary bladder [nTPM]":"6.9","Tissue RNA - vagina [nTPM]":"9.8","Tissue RNA - white matter [nTPM]":"6.9","Cell RNA - A-431 [nTPM]":"36.5","Cell RNA - A549 [nTPM]":"35.0","Cell RNA - AF22 [nTPM]":"42.2","Cell RNA - AN3-CA [nTPM]":"34.5","Cell RNA - ASC diff [nTPM]":"5.8","Cell RNA - ASC TERT1 [nTPM]":"11.0","Cell RNA - BEWO [nTPM]":"58.7","Cell RNA - BJ [nTPM]":"21.8","Cell RNA - BJ hTERT+ [nTPM]":"10.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"25.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"28.5","Cell RNA - CACO-2 [nTPM]":"44.1","Cell RNA - CAPAN-2 [nTPM]":"58.6","Cell RNA - Daudi [nTPM]":"49.2","Cell RNA - EFO-21 [nTPM]":"23.9","Cell RNA - fHDF\/TERT166 [nTPM]":"10.8","Cell RNA - GAMG [nTPM]":"23.6","Cell RNA - HaCaT [nTPM]":"35.0","Cell RNA - HAP1 [nTPM]":"31.7","Cell RNA - HBEC3-KT [nTPM]":"28.9","Cell RNA - HBF TERT88 [nTPM]":"21.3","Cell RNA - HDLM-2 [nTPM]":"43.4","Cell RNA - HEK 293 [nTPM]":"66.6","Cell RNA - HEL [nTPM]":"47.4","Cell RNA - HeLa [nTPM]":"71.0","Cell RNA - Hep G2 [nTPM]":"25.4","Cell RNA - HHSteC [nTPM]":"2.1","Cell RNA - HL-60 [nTPM]":"37.4","Cell RNA - HMC-1 [nTPM]":"35.0","Cell RNA - HSkMC [nTPM]":"11.9","Cell RNA - hTCEpi [nTPM]":"13.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.6","Cell RNA - hTERT-HME1 [nTPM]":"24.8","Cell RNA - hTERT-RPE1 [nTPM]":"16.9","Cell RNA - HUVEC TERT2 [nTPM]":"12.6","Cell RNA - JURKAT [nTPM]":"55.2","Cell RNA - K-562 [nTPM]":"26.6","Cell RNA - Karpas-707 [nTPM]":"103.3","Cell RNA - LHCN-M2 [nTPM]":"17.6","Cell RNA - MCF7 [nTPM]":"30.9","Cell RNA - MOLT-4 [nTPM]":"64.5","Cell RNA - NB-4 [nTPM]":"60.7","Cell RNA - NTERA-2 [nTPM]":"84.0","Cell RNA - OE19 [nTPM]":"39.9","Cell RNA - PC-3 [nTPM]":"19.5","Cell RNA - REH [nTPM]":"55.0","Cell RNA - RH-30 [nTPM]":"53.3","Cell RNA - RPMI-8226 [nTPM]":"66.2","Cell RNA - RPTEC TERT1 [nTPM]":"13.3","Cell RNA - RT4 [nTPM]":"38.5","Cell RNA - SCLC-21H [nTPM]":"30.2","Cell RNA - SH-SY5Y [nTPM]":"21.7","Cell RNA - SiHa [nTPM]":"23.4","Cell RNA - SK-BR-3 [nTPM]":"33.2","Cell RNA - SK-MEL-30 [nTPM]":"10.4","Cell RNA - SuSa [nTPM]":"65.0","Cell RNA - T-47d [nTPM]":"27.3","Cell RNA - THP-1 [nTPM]":"25.5","Cell RNA - TIME [nTPM]":"8.2","Cell RNA - U-138 MG [nTPM]":"22.0","Cell RNA - U-2 OS [nTPM]":"42.1","Cell RNA - U-2197 [nTPM]":"42.2","Cell RNA - U-251 MG [nTPM]":"40.0","Cell RNA - U-266\/70 [nTPM]":"39.4","Cell RNA - U-266\/84 [nTPM]":"29.6","Cell RNA - U-698 [nTPM]":"95.3","Cell RNA - U-87 MG [nTPM]":"24.6","Cell RNA - U-937 [nTPM]":"32.5","Cell RNA - WM-115 [nTPM]":"20.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"0.8","Blood RNA - gdT-cell [nTPM]":"2.0","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"1.5","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.5","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"2.6","Blood RNA - naive CD4 T-cell [nTPM]":"2.0","Blood RNA - naive CD8 T-cell [nTPM]":"2.6","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"2.2","Blood RNA - non-classical monocyte [nTPM]":"4.4","Blood RNA - plasmacytoid DC [nTPM]":"2.4","Blood RNA - T-reg [nTPM]":"2.0","Blood RNA - total PBMC [nTPM]":"1.3","Brain RNA - amygdala [nTPM]":"6.0","Brain RNA - basal ganglia [nTPM]":"6.8","Brain RNA - cerebellum [nTPM]":"6.9","Brain RNA - cerebral cortex [nTPM]":"7.3","Brain RNA - hippocampal formation [nTPM]":"6.0","Brain RNA - hypothalamus [nTPM]":"6.1","Brain RNA - medulla oblongata [nTPM]":"6.9","Brain RNA - midbrain [nTPM]":"6.4","Brain RNA - pons [nTPM]":"6.9","Brain RNA - spinal cord [nTPM]":"6.1","Brain RNA - thalamus [nTPM]":"6.7","Brain RNA - white matter [nTPM]":"6.9","Single Cell Type RNA - Adipocytes [nTPM]":"10.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.5","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"9.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"9.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"6.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.6","Single Cell Type RNA - dendritic cells [nTPM]":"8.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.9","Single Cell Type RNA - Endothelial cells [nTPM]":"5.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"15.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.5","Single Cell Type RNA - Fibroblasts [nTPM]":"5.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.4","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"15.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"7.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.2","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.5","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"4.1","Single Cell Type RNA - Langerhans cells [nTPM]":"5.4","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"4.4","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"3.5","Single Cell Type RNA - Muller glia cells [nTPM]":"2.7","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.2","Single Cell Type RNA - Paneth cells [nTPM]":"2.7","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"17.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"25.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.8","Single Cell Type RNA - Spermatocytes [nTPM]":"5.3","Single Cell Type RNA - Spermatogonia [nTPM]":"18.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.6","Single Cell Type RNA - T-cells [nTPM]":"8.4","Single Cell Type RNA - Theca cells [nTPM]":"4.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.5","Single Cell Type RNA - Urothelial cells [nTPM]":"5.1"},{"Gene":"DDX3X","Gene synonym":["DBX","DDX14","DDX3","HLP2"],"Ensembl":"ENSG00000215301","Gene description":"DEAD-box helicase 3 X-linked","Uniprot":["O00571"],"Chromosome":"X","Position":"41333348-41364472","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Chromosome partition","Host-virus interaction","Immunity","Innate immunity","Ribosome biogenesis","Transcription","Transcription regulation","Translation regulation"],"Molecular function":["DNA-binding","Helicase","Hydrolase","RNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"887.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001648","HPA005631","HPA059585"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"260000","Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA001648":"AB_1078635","HPA005631":"AB_1078633","HPA059585":"AB_2684073"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Tissue RNA - adipose tissue [nTPM]":"164.7","Tissue RNA - adrenal gland [nTPM]":"123.2","Tissue RNA - amygdala [nTPM]":"28.7","Tissue RNA - appendix [nTPM]":"113.3","Tissue RNA - basal ganglia [nTPM]":"29.9","Tissue RNA - bone marrow [nTPM]":"146.1","Tissue RNA - breast [nTPM]":"99.8","Tissue RNA - cerebellum [nTPM]":"31.9","Tissue RNA - cerebral cortex [nTPM]":"37.3","Tissue RNA - cervix [nTPM]":"102.4","Tissue RNA - choroid plexus [nTPM]":"38.8","Tissue RNA - colon [nTPM]":"85.6","Tissue RNA - duodenum [nTPM]":"80.7","Tissue RNA - endometrium 1 [nTPM]":"123.4","Tissue RNA - epididymis [nTPM]":"39.1","Tissue RNA - esophagus [nTPM]":"107.6","Tissue RNA - fallopian tube [nTPM]":"108.8","Tissue RNA - gallbladder [nTPM]":"111.0","Tissue RNA - heart muscle [nTPM]":"96.4","Tissue RNA - hippocampal formation [nTPM]":"27.0","Tissue RNA - hypothalamus [nTPM]":"36.0","Tissue RNA - kidney [nTPM]":"110.5","Tissue RNA - liver [nTPM]":"130.6","Tissue RNA - lung [nTPM]":"103.5","Tissue RNA - lymph node [nTPM]":"118.7","Tissue RNA - medulla oblongata [nTPM]":"33.6","Tissue RNA - midbrain [nTPM]":"29.8","Tissue RNA - ovary [nTPM]":"108.1","Tissue RNA - pancreas [nTPM]":"76.9","Tissue RNA - parathyroid gland [nTPM]":"133.0","Tissue RNA - pituitary gland [nTPM]":"52.5","Tissue RNA - placenta [nTPM]":"107.3","Tissue RNA - pons [nTPM]":"34.2","Tissue RNA - prostate [nTPM]":"68.7","Tissue RNA - rectum [nTPM]":"75.8","Tissue RNA - retina [nTPM]":"81.9","Tissue RNA - salivary gland [nTPM]":"72.9","Tissue RNA - seminal vesicle [nTPM]":"64.8","Tissue RNA - skeletal muscle [nTPM]":"126.9","Tissue RNA - skin 1 [nTPM]":"91.2","Tissue RNA - small intestine [nTPM]":"81.6","Tissue RNA - smooth muscle [nTPM]":"145.1","Tissue RNA - spinal cord [nTPM]":"32.4","Tissue RNA - spleen [nTPM]":"103.2","Tissue RNA - stomach 1 [nTPM]":"84.4","Tissue RNA - testis [nTPM]":"43.0","Tissue RNA - thalamus [nTPM]":"30.9","Tissue RNA - thymus [nTPM]":"169.6","Tissue RNA - thyroid gland [nTPM]":"104.3","Tissue RNA - tongue [nTPM]":"112.5","Tissue RNA - tonsil [nTPM]":"111.5","Tissue RNA - urinary bladder [nTPM]":"153.3","Tissue RNA - vagina [nTPM]":"97.7","Tissue RNA - white matter [nTPM]":"34.7","Cell RNA - A-431 [nTPM]":"230.5","Cell RNA - A549 [nTPM]":"225.6","Cell RNA - AF22 [nTPM]":"236.3","Cell RNA - AN3-CA [nTPM]":"122.3","Cell RNA - ASC diff [nTPM]":"273.6","Cell RNA - ASC TERT1 [nTPM]":"211.1","Cell RNA - BEWO [nTPM]":"136.4","Cell RNA - BJ [nTPM]":"150.6","Cell RNA - BJ hTERT+ [nTPM]":"239.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"167.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"132.3","Cell RNA - CACO-2 [nTPM]":"238.8","Cell RNA - CAPAN-2 [nTPM]":"141.4","Cell RNA - Daudi [nTPM]":"2.5","Cell RNA - EFO-21 [nTPM]":"103.9","Cell RNA - fHDF\/TERT166 [nTPM]":"185.8","Cell RNA - GAMG [nTPM]":"212.4","Cell RNA - HaCaT [nTPM]":"149.4","Cell RNA - HAP1 [nTPM]":"292.2","Cell RNA - HBEC3-KT [nTPM]":"235.0","Cell RNA - HBF TERT88 [nTPM]":"248.3","Cell RNA - HDLM-2 [nTPM]":"130.2","Cell RNA - HEK 293 [nTPM]":"232.9","Cell RNA - HEL [nTPM]":"132.6","Cell RNA - HeLa [nTPM]":"237.6","Cell RNA - Hep G2 [nTPM]":"152.1","Cell RNA - HHSteC [nTPM]":"140.5","Cell RNA - HL-60 [nTPM]":"253.8","Cell RNA - HMC-1 [nTPM]":"236.4","Cell RNA - HSkMC [nTPM]":"159.1","Cell RNA - hTCEpi [nTPM]":"150.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"278.4","Cell RNA - hTERT-HME1 [nTPM]":"270.3","Cell RNA - hTERT-RPE1 [nTPM]":"204.1","Cell RNA - HUVEC TERT2 [nTPM]":"258.3","Cell RNA - JURKAT [nTPM]":"131.5","Cell RNA - K-562 [nTPM]":"258.4","Cell RNA - Karpas-707 [nTPM]":"134.5","Cell RNA - LHCN-M2 [nTPM]":"158.9","Cell RNA - MCF7 [nTPM]":"157.8","Cell RNA - MOLT-4 [nTPM]":"163.0","Cell RNA - NB-4 [nTPM]":"83.2","Cell RNA - NTERA-2 [nTPM]":"212.2","Cell RNA - OE19 [nTPM]":"121.3","Cell RNA - PC-3 [nTPM]":"114.2","Cell RNA - REH [nTPM]":"187.8","Cell RNA - RH-30 [nTPM]":"223.3","Cell RNA - RPMI-8226 [nTPM]":"182.6","Cell RNA - RPTEC TERT1 [nTPM]":"143.7","Cell RNA - RT4 [nTPM]":"279.1","Cell RNA - SCLC-21H [nTPM]":"147.1","Cell RNA - SH-SY5Y [nTPM]":"220.0","Cell RNA - SiHa [nTPM]":"352.3","Cell RNA - SK-BR-3 [nTPM]":"184.3","Cell RNA - SK-MEL-30 [nTPM]":"194.3","Cell RNA - SuSa [nTPM]":"248.9","Cell RNA - T-47d [nTPM]":"158.9","Cell RNA - THP-1 [nTPM]":"172.4","Cell RNA - TIME [nTPM]":"224.5","Cell RNA - U-138 MG [nTPM]":"159.6","Cell RNA - U-2 OS [nTPM]":"166.3","Cell RNA - U-2197 [nTPM]":"178.7","Cell RNA - U-251 MG [nTPM]":"188.2","Cell RNA - U-266\/70 [nTPM]":"153.6","Cell RNA - U-266\/84 [nTPM]":"194.0","Cell RNA - U-698 [nTPM]":"215.7","Cell RNA - U-87 MG [nTPM]":"161.5","Cell RNA - U-937 [nTPM]":"156.1","Cell RNA - WM-115 [nTPM]":"151.5","Blood RNA - basophil [nTPM]":"50.8","Blood RNA - classical monocyte [nTPM]":"39.0","Blood RNA - eosinophil [nTPM]":"30.7","Blood RNA - gdT-cell [nTPM]":"23.3","Blood RNA - intermediate monocyte [nTPM]":"35.3","Blood RNA - MAIT T-cell [nTPM]":"33.5","Blood RNA - memory B-cell [nTPM]":"21.0","Blood RNA - memory CD4 T-cell [nTPM]":"23.3","Blood RNA - memory CD8 T-cell [nTPM]":"26.3","Blood RNA - myeloid DC [nTPM]":"34.7","Blood RNA - naive B-cell [nTPM]":"13.0","Blood RNA - naive CD4 T-cell [nTPM]":"25.4","Blood RNA - naive CD8 T-cell [nTPM]":"25.3","Blood RNA - neutrophil [nTPM]":"54.0","Blood RNA - NK-cell [nTPM]":"30.7","Blood RNA - non-classical monocyte [nTPM]":"39.4","Blood RNA - plasmacytoid DC [nTPM]":"11.7","Blood RNA - T-reg [nTPM]":"24.8","Blood RNA - total PBMC [nTPM]":"37.8","Brain RNA - amygdala [nTPM]":"28.7","Brain RNA - basal ganglia [nTPM]":"29.9","Brain RNA - cerebellum [nTPM]":"31.9","Brain RNA - cerebral cortex [nTPM]":"37.3","Brain RNA - hippocampal formation [nTPM]":"27.0","Brain RNA - hypothalamus [nTPM]":"36.0","Brain RNA - medulla oblongata [nTPM]":"33.6","Brain RNA - midbrain [nTPM]":"29.8","Brain RNA - pons [nTPM]":"34.2","Brain RNA - spinal cord [nTPM]":"32.4","Brain RNA - thalamus [nTPM]":"30.9","Brain RNA - white matter [nTPM]":"34.7","Single Cell Type RNA - Adipocytes [nTPM]":"466.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"86.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"150.0","Single Cell Type RNA - Astrocytes [nTPM]":"66.9","Single Cell Type RNA - B-cells [nTPM]":"280.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"264.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"160.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"63.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"191.8","Single Cell Type RNA - Bipolar cells [nTPM]":"77.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"295.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"237.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"158.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"81.5","Single Cell Type RNA - Club cells [nTPM]":"96.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"58.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"131.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"94.6","Single Cell Type RNA - dendritic cells [nTPM]":"415.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"231.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"43.0","Single Cell Type RNA - Ductal cells [nTPM]":"64.3","Single Cell Type RNA - Early spermatids [nTPM]":"370.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"261.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"237.7","Single Cell Type RNA - Endothelial cells [nTPM]":"238.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"183.7","Single Cell Type RNA - Erythroid cells [nTPM]":"113.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"43.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"85.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"95.1","Single Cell Type RNA - Fibroblasts [nTPM]":"191.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"178.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"290.1","Single Cell Type RNA - granulocytes [nTPM]":"165.5","Single Cell Type RNA - Granulosa cells [nTPM]":"180.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"144.2","Single Cell Type RNA - Hepatocytes [nTPM]":"174.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"123.1","Single Cell Type RNA - Horizontal cells [nTPM]":"60.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"47.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"161.4","Single Cell Type RNA - Ionocytes [nTPM]":"71.2","Single Cell Type RNA - Kupffer cells [nTPM]":"208.7","Single Cell Type RNA - Langerhans cells [nTPM]":"269.1","Single Cell Type RNA - Late spermatids [nTPM]":"887.5","Single Cell Type RNA - Leydig cells [nTPM]":"66.5","Single Cell Type RNA - Macrophages [nTPM]":"319.0","Single Cell Type RNA - Melanocytes [nTPM]":"128.1","Single Cell Type RNA - Microglial cells [nTPM]":"47.8","Single Cell Type RNA - monocytes [nTPM]":"112.2","Single Cell Type RNA - Muller glia cells [nTPM]":"90.0","Single Cell Type RNA - NK-cells [nTPM]":"79.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"44.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"63.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"114.1","Single Cell Type RNA - Paneth cells [nTPM]":"156.7","Single Cell Type RNA - Peritubular cells [nTPM]":"62.8","Single Cell Type RNA - Plasma cells [nTPM]":"241.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"145.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"234.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"87.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"102.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"127.1","Single Cell Type RNA - Sertoli cells [nTPM]":"72.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"351.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"210.1","Single Cell Type RNA - Spermatocytes [nTPM]":"30.6","Single Cell Type RNA - Spermatogonia [nTPM]":"57.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"212.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"333.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"172.9","Single Cell Type RNA - T-cells [nTPM]":"342.4","Single Cell Type RNA - Theca cells [nTPM]":"144.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"129.1","Single Cell Type RNA - Urothelial cells [nTPM]":"225.8"},{"Gene":"DDX3Y","Gene synonym":["DBY"],"Ensembl":"ENSG00000067048","Gene description":"DEAD-box helicase 3 Y-linked","Uniprot":["O15523"],"Chromosome":"Y","Position":"12904108-12920478","Protein class":["Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["DNA-binding","Helicase","Hydrolase","RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"96.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"275.5","Late spermatids":"575.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"cerebral cortex":"31.8"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"153.7","HEL":"156.8","U-266\/84":"133.1","U-698":"112.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001648","HPA005631","HPA059583"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA001648":"AB_1078635","HPA005631":"AB_1078633","HPA059583":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.70e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-2"},"Tissue RNA - adipose tissue [nTPM]":"29.0","Tissue RNA - adrenal gland [nTPM]":"26.1","Tissue RNA - amygdala [nTPM]":"2.8","Tissue RNA - appendix [nTPM]":"15.2","Tissue RNA - basal ganglia [nTPM]":"2.9","Tissue RNA - bone marrow [nTPM]":"96.0","Tissue RNA - breast [nTPM]":"20.7","Tissue RNA - cerebellum [nTPM]":"5.5","Tissue RNA - cerebral cortex [nTPM]":"31.8","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"6.6","Tissue RNA - colon [nTPM]":"25.8","Tissue RNA - duodenum [nTPM]":"12.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"26.8","Tissue RNA - esophagus [nTPM]":"18.5","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"18.7","Tissue RNA - heart muscle [nTPM]":"19.1","Tissue RNA - hippocampal formation [nTPM]":"2.7","Tissue RNA - hypothalamus [nTPM]":"5.5","Tissue RNA - kidney [nTPM]":"23.7","Tissue RNA - liver [nTPM]":"22.0","Tissue RNA - lung [nTPM]":"27.4","Tissue RNA - lymph node [nTPM]":"9.6","Tissue RNA - medulla oblongata [nTPM]":"2.8","Tissue RNA - midbrain [nTPM]":"3.3","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"14.8","Tissue RNA - parathyroid gland [nTPM]":"12.4","Tissue RNA - pituitary gland [nTPM]":"25.1","Tissue RNA - placenta [nTPM]":"22.1","Tissue RNA - pons [nTPM]":"3.2","Tissue RNA - prostate [nTPM]":"33.6","Tissue RNA - rectum [nTPM]":"24.0","Tissue RNA - retina [nTPM]":"23.6","Tissue RNA - salivary gland [nTPM]":"18.5","Tissue RNA - seminal vesicle [nTPM]":"31.3","Tissue RNA - skeletal muscle [nTPM]":"19.9","Tissue RNA - skin 1 [nTPM]":"20.2","Tissue RNA - small intestine [nTPM]":"25.9","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"2.3","Tissue RNA - spleen [nTPM]":"26.5","Tissue RNA - stomach 1 [nTPM]":"19.8","Tissue RNA - testis [nTPM]":"70.1","Tissue RNA - thalamus [nTPM]":"3.8","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"22.0","Tissue RNA - tongue [nTPM]":"28.1","Tissue RNA - tonsil [nTPM]":"23.6","Tissue RNA - urinary bladder [nTPM]":"22.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"4.6","Cell RNA - A-431 [nTPM]":"0.7","Cell RNA - A549 [nTPM]":"28.3","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"20.0","Cell RNA - BJ [nTPM]":"69.3","Cell RNA - BJ hTERT+ [nTPM]":"49.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"35.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"44.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"153.7","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"69.5","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"63.2","Cell RNA - HDLM-2 [nTPM]":"38.8","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"156.8","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"46.5","Cell RNA - HHSteC [nTPM]":"34.2","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"37.4","Cell RNA - hTCEpi [nTPM]":"43.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"15.2","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"43.1","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"61.8","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"27.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"18.0","Cell RNA - RPMI-8226 [nTPM]":"28.2","Cell RNA - RPTEC TERT1 [nTPM]":"38.2","Cell RNA - RT4 [nTPM]":"41.5","Cell RNA - SCLC-21H [nTPM]":"44.5","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"51.4","Cell RNA - SuSa [nTPM]":"43.5","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"36.5","Cell RNA - TIME [nTPM]":"49.1","Cell RNA - U-138 MG [nTPM]":"55.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"45.8","Cell RNA - U-266\/70 [nTPM]":"78.7","Cell RNA - U-266\/84 [nTPM]":"133.1","Cell RNA - U-698 [nTPM]":"112.8","Cell RNA - U-87 MG [nTPM]":"6.9","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"1.5","Blood RNA - classical monocyte [nTPM]":"3.8","Blood RNA - eosinophil [nTPM]":"3.2","Blood RNA - gdT-cell [nTPM]":"4.4","Blood RNA - intermediate monocyte [nTPM]":"3.9","Blood RNA - MAIT T-cell [nTPM]":"4.0","Blood RNA - memory B-cell [nTPM]":"3.2","Blood RNA - memory CD4 T-cell [nTPM]":"3.3","Blood RNA - memory CD8 T-cell [nTPM]":"3.7","Blood RNA - myeloid DC [nTPM]":"4.9","Blood RNA - naive B-cell [nTPM]":"2.7","Blood RNA - naive CD4 T-cell [nTPM]":"3.9","Blood RNA - naive CD8 T-cell [nTPM]":"3.5","Blood RNA - neutrophil [nTPM]":"3.5","Blood RNA - NK-cell [nTPM]":"3.4","Blood RNA - non-classical monocyte [nTPM]":"2.4","Blood RNA - plasmacytoid DC [nTPM]":"1.4","Blood RNA - T-reg [nTPM]":"3.0","Blood RNA - total PBMC [nTPM]":"3.2","Brain RNA - amygdala [nTPM]":"2.8","Brain RNA - basal ganglia [nTPM]":"2.9","Brain RNA - cerebellum [nTPM]":"5.5","Brain RNA - cerebral cortex [nTPM]":"31.8","Brain RNA - hippocampal formation [nTPM]":"2.7","Brain RNA - hypothalamus [nTPM]":"5.5","Brain RNA - medulla oblongata [nTPM]":"2.8","Brain RNA - midbrain [nTPM]":"3.3","Brain RNA - pons [nTPM]":"3.2","Brain RNA - spinal cord [nTPM]":"2.3","Brain RNA - thalamus [nTPM]":"3.8","Brain RNA - white matter [nTPM]":"4.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"75.8","Single Cell Type RNA - Astrocytes [nTPM]":"10.1","Single Cell Type RNA - B-cells [nTPM]":"58.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"94.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"92.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"37.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"89.4","Single Cell Type RNA - Bipolar cells [nTPM]":"53.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"26.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"41.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"38.3","Single Cell Type RNA - dendritic cells [nTPM]":"13.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"13.9","Single Cell Type RNA - Early spermatids [nTPM]":"275.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"56.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.0","Single Cell Type RNA - Erythroid cells [nTPM]":"24.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.9","Single Cell Type RNA - Fibroblasts [nTPM]":"63.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"56.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"92.9","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"42.1","Single Cell Type RNA - Hepatocytes [nTPM]":"9.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.1","Single Cell Type RNA - Horizontal cells [nTPM]":"42.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.3","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"64.1","Single Cell Type RNA - Langerhans cells [nTPM]":"127.5","Single Cell Type RNA - Late spermatids [nTPM]":"575.3","Single Cell Type RNA - Leydig cells [nTPM]":"38.8","Single Cell Type RNA - Macrophages [nTPM]":"58.2","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"27.8","Single Cell Type RNA - Muller glia cells [nTPM]":"53.7","Single Cell Type RNA - NK-cells [nTPM]":"26.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.0","Single Cell Type RNA - Paneth cells [nTPM]":"8.8","Single Cell Type RNA - Peritubular cells [nTPM]":"39.5","Single Cell Type RNA - Plasma cells [nTPM]":"54.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"70.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"101.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"49.3","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"56.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"39.2","Single Cell Type RNA - Spermatocytes [nTPM]":"67.2","Single Cell Type RNA - Spermatogonia [nTPM]":"70.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"43.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"80.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"37.8","Single Cell Type RNA - T-cells [nTPM]":"66.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.1","Single Cell Type RNA - Urothelial cells [nTPM]":"75.0"},{"Gene":"DDX41","Gene synonym":["ABS","MGC8828"],"Ensembl":"ENSG00000183258","Gene description":"DEAD-box helicase 41","Uniprot":["Q9UJV9"],"Chromosome":"5","Position":"177511577-177516961","Protein class":["Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":["Helicase","Hydrolase","RNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017911","HPA048803"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA017911":"AB_1847558","HPA048803":"AB_2680527"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.21e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Tissue RNA - adipose tissue [nTPM]":"26.5","Tissue RNA - adrenal gland [nTPM]":"29.0","Tissue RNA - amygdala [nTPM]":"15.1","Tissue RNA - appendix [nTPM]":"28.7","Tissue RNA - basal ganglia [nTPM]":"16.1","Tissue RNA - bone marrow [nTPM]":"22.3","Tissue RNA - breast [nTPM]":"25.4","Tissue RNA - cerebellum [nTPM]":"13.1","Tissue RNA - cerebral cortex [nTPM]":"21.9","Tissue RNA - cervix [nTPM]":"26.1","Tissue RNA - choroid plexus [nTPM]":"13.7","Tissue RNA - colon [nTPM]":"26.5","Tissue RNA - duodenum [nTPM]":"24.8","Tissue RNA - endometrium 1 [nTPM]":"25.2","Tissue RNA - epididymis [nTPM]":"16.8","Tissue RNA - esophagus [nTPM]":"33.7","Tissue RNA - fallopian tube [nTPM]":"30.6","Tissue RNA - gallbladder [nTPM]":"18.3","Tissue RNA - heart muscle [nTPM]":"18.9","Tissue RNA - hippocampal formation [nTPM]":"17.8","Tissue RNA - hypothalamus [nTPM]":"14.2","Tissue RNA - kidney [nTPM]":"26.8","Tissue RNA - liver [nTPM]":"27.1","Tissue RNA - lung [nTPM]":"24.5","Tissue RNA - lymph node [nTPM]":"24.7","Tissue RNA - medulla oblongata [nTPM]":"15.8","Tissue RNA - midbrain [nTPM]":"13.7","Tissue RNA - ovary [nTPM]":"28.6","Tissue RNA - pancreas [nTPM]":"23.5","Tissue RNA - parathyroid gland [nTPM]":"31.2","Tissue RNA - pituitary gland [nTPM]":"18.0","Tissue RNA - placenta [nTPM]":"22.8","Tissue RNA - pons [nTPM]":"16.0","Tissue RNA - prostate [nTPM]":"22.3","Tissue RNA - rectum [nTPM]":"19.3","Tissue RNA - retina [nTPM]":"14.6","Tissue RNA - salivary gland [nTPM]":"28.7","Tissue RNA - seminal vesicle [nTPM]":"19.1","Tissue RNA - skeletal muscle [nTPM]":"43.4","Tissue RNA - skin 1 [nTPM]":"35.0","Tissue RNA - small intestine [nTPM]":"28.7","Tissue RNA - smooth muscle [nTPM]":"20.1","Tissue RNA - spinal cord [nTPM]":"12.8","Tissue RNA - spleen [nTPM]":"26.7","Tissue RNA - stomach 1 [nTPM]":"26.7","Tissue RNA - testis [nTPM]":"17.9","Tissue RNA - thalamus [nTPM]":"16.2","Tissue RNA - thymus [nTPM]":"24.3","Tissue RNA - thyroid gland [nTPM]":"29.0","Tissue RNA - tongue [nTPM]":"20.3","Tissue RNA - tonsil [nTPM]":"25.0","Tissue RNA - urinary bladder [nTPM]":"24.8","Tissue RNA - vagina [nTPM]":"27.6","Tissue RNA - white matter [nTPM]":"16.4","Cell RNA - A-431 [nTPM]":"62.1","Cell RNA - A549 [nTPM]":"71.4","Cell RNA - AF22 [nTPM]":"42.4","Cell RNA - AN3-CA [nTPM]":"44.9","Cell RNA - ASC diff [nTPM]":"43.4","Cell RNA - ASC TERT1 [nTPM]":"45.2","Cell RNA - BEWO [nTPM]":"125.1","Cell RNA - BJ [nTPM]":"58.4","Cell RNA - BJ hTERT+ [nTPM]":"35.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"47.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"36.1","Cell RNA - CACO-2 [nTPM]":"107.7","Cell RNA - CAPAN-2 [nTPM]":"61.3","Cell RNA - Daudi [nTPM]":"67.2","Cell RNA - EFO-21 [nTPM]":"83.3","Cell RNA - fHDF\/TERT166 [nTPM]":"57.6","Cell RNA - GAMG [nTPM]":"67.6","Cell RNA - HaCaT [nTPM]":"47.8","Cell RNA - HAP1 [nTPM]":"57.2","Cell RNA - HBEC3-KT [nTPM]":"128.5","Cell RNA - HBF TERT88 [nTPM]":"33.2","Cell RNA - HDLM-2 [nTPM]":"175.4","Cell RNA - HEK 293 [nTPM]":"68.0","Cell RNA - HEL [nTPM]":"90.5","Cell RNA - HeLa [nTPM]":"70.8","Cell RNA - Hep G2 [nTPM]":"66.5","Cell RNA - HHSteC [nTPM]":"52.5","Cell RNA - HL-60 [nTPM]":"89.3","Cell RNA - HMC-1 [nTPM]":"82.3","Cell RNA - HSkMC [nTPM]":"48.7","Cell RNA - hTCEpi [nTPM]":"47.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"45.3","Cell RNA - hTERT-HME1 [nTPM]":"59.0","Cell RNA - hTERT-RPE1 [nTPM]":"43.5","Cell RNA - HUVEC TERT2 [nTPM]":"53.4","Cell RNA - JURKAT [nTPM]":"68.1","Cell RNA - K-562 [nTPM]":"72.3","Cell RNA - Karpas-707 [nTPM]":"50.0","Cell RNA - LHCN-M2 [nTPM]":"55.6","Cell RNA - MCF7 [nTPM]":"135.5","Cell RNA - MOLT-4 [nTPM]":"80.6","Cell RNA - NB-4 [nTPM]":"45.9","Cell RNA - NTERA-2 [nTPM]":"62.0","Cell RNA - OE19 [nTPM]":"59.0","Cell RNA - PC-3 [nTPM]":"61.3","Cell RNA - REH [nTPM]":"72.7","Cell RNA - RH-30 [nTPM]":"48.1","Cell RNA - RPMI-8226 [nTPM]":"86.2","Cell RNA - RPTEC TERT1 [nTPM]":"50.5","Cell RNA - RT4 [nTPM]":"78.8","Cell RNA - SCLC-21H [nTPM]":"45.0","Cell RNA - SH-SY5Y [nTPM]":"41.9","Cell RNA - SiHa [nTPM]":"64.6","Cell RNA - SK-BR-3 [nTPM]":"83.2","Cell RNA - SK-MEL-30 [nTPM]":"56.5","Cell RNA - SuSa [nTPM]":"27.1","Cell RNA - T-47d [nTPM]":"54.6","Cell RNA - THP-1 [nTPM]":"110.2","Cell RNA - TIME [nTPM]":"51.3","Cell RNA - U-138 MG [nTPM]":"74.4","Cell RNA - U-2 OS [nTPM]":"42.8","Cell RNA - U-2197 [nTPM]":"43.6","Cell RNA - U-251 MG [nTPM]":"87.6","Cell RNA - U-266\/70 [nTPM]":"49.6","Cell RNA - U-266\/84 [nTPM]":"75.9","Cell RNA - U-698 [nTPM]":"120.1","Cell RNA - U-87 MG [nTPM]":"81.3","Cell RNA - U-937 [nTPM]":"100.1","Cell RNA - WM-115 [nTPM]":"47.0","Blood RNA - basophil [nTPM]":"14.3","Blood RNA - classical monocyte [nTPM]":"31.4","Blood RNA - eosinophil [nTPM]":"22.3","Blood RNA - gdT-cell [nTPM]":"18.3","Blood RNA - intermediate monocyte [nTPM]":"28.5","Blood RNA - MAIT T-cell [nTPM]":"23.5","Blood RNA - memory B-cell [nTPM]":"17.0","Blood RNA - memory CD4 T-cell [nTPM]":"18.3","Blood RNA - memory CD8 T-cell [nTPM]":"16.8","Blood RNA - myeloid DC [nTPM]":"27.2","Blood RNA - naive B-cell [nTPM]":"14.4","Blood RNA - naive CD4 T-cell [nTPM]":"14.6","Blood RNA - naive CD8 T-cell [nTPM]":"18.8","Blood RNA - neutrophil [nTPM]":"9.2","Blood RNA - NK-cell [nTPM]":"25.8","Blood RNA - non-classical monocyte [nTPM]":"31.4","Blood RNA - plasmacytoid DC [nTPM]":"11.2","Blood RNA - T-reg [nTPM]":"18.8","Blood RNA - total PBMC [nTPM]":"25.6","Brain RNA - amygdala [nTPM]":"15.1","Brain RNA - basal ganglia [nTPM]":"16.1","Brain RNA - cerebellum [nTPM]":"13.1","Brain RNA - cerebral cortex [nTPM]":"21.9","Brain RNA - hippocampal formation [nTPM]":"17.8","Brain RNA - hypothalamus [nTPM]":"14.2","Brain RNA - medulla oblongata [nTPM]":"15.8","Brain RNA - midbrain [nTPM]":"13.7","Brain RNA - pons [nTPM]":"16.0","Brain RNA - spinal cord [nTPM]":"12.8","Brain RNA - thalamus [nTPM]":"16.2","Brain RNA - white matter [nTPM]":"16.4","Single Cell Type RNA - Adipocytes [nTPM]":"17.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.8","Single Cell Type RNA - Astrocytes [nTPM]":"7.8","Single Cell Type RNA - B-cells [nTPM]":"20.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"21.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"37.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.2","Single Cell Type RNA - Bipolar cells [nTPM]":"16.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"24.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"46.6","Single Cell Type RNA - dendritic cells [nTPM]":"22.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"22.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"41.1","Single Cell Type RNA - Ductal cells [nTPM]":"42.1","Single Cell Type RNA - Early spermatids [nTPM]":"11.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.5","Single Cell Type RNA - Endothelial cells [nTPM]":"22.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.4","Single Cell Type RNA - Erythroid cells [nTPM]":"25.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"39.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"63.2","Single Cell Type RNA - Fibroblasts [nTPM]":"17.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.2","Single Cell Type RNA - granulocytes [nTPM]":"29.8","Single Cell Type RNA - Granulosa cells [nTPM]":"21.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.1","Single Cell Type RNA - Hepatocytes [nTPM]":"18.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"48.8","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"27.0","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"23.5","Single Cell Type RNA - Langerhans cells [nTPM]":"15.4","Single Cell Type RNA - Late spermatids [nTPM]":"22.9","Single Cell Type RNA - Leydig cells [nTPM]":"14.9","Single Cell Type RNA - Macrophages [nTPM]":"22.2","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"34.6","Single Cell Type RNA - Muller glia cells [nTPM]":"23.9","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"33.5","Single Cell Type RNA - Paneth cells [nTPM]":"23.9","Single Cell Type RNA - Peritubular cells [nTPM]":"21.1","Single Cell Type RNA - Plasma cells [nTPM]":"23.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"29.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"40.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.3","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"29.0","Single Cell Type RNA - Spermatocytes [nTPM]":"24.5","Single Cell Type RNA - Spermatogonia [nTPM]":"26.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"37.5","Single Cell Type RNA - T-cells [nTPM]":"19.0","Single Cell Type RNA - Theca cells [nTPM]":"25.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"31.0","Single Cell Type RNA - Urothelial cells [nTPM]":"22.7"},{"Gene":"DDX58","Gene synonym":["DKFZp434J1111","FLJ13599","RIG-1","RIG-I","RIG1"],"Ensembl":"ENSG00000107201","Gene description":"DExD\/H-box helicase 58","Uniprot":["O95786"],"Chromosome":"9","Position":"32455302-32526208","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Antiviral defense","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":["Helicase","Hydrolase","RNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"41.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"BJ hTERT+ SV40 Large T+":"79.0","BJ hTERT+ SV40 Large T+ RasG12V":"76.0","GAMG":"22.8"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB012643","HPA047193","HPA073217"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB012643":null,"HPA047193":"AB_2679978","HPA073217":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.46e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.66e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.3","Tissue RNA - adrenal gland [nTPM]":"4.9","Tissue RNA - amygdala [nTPM]":"3.5","Tissue RNA - appendix [nTPM]":"7.5","Tissue RNA - basal ganglia [nTPM]":"2.9","Tissue RNA - bone marrow [nTPM]":"1.3","Tissue RNA - breast [nTPM]":"6.0","Tissue RNA - cerebellum [nTPM]":"3.0","Tissue RNA - cerebral cortex [nTPM]":"4.3","Tissue RNA - cervix [nTPM]":"7.1","Tissue RNA - choroid plexus [nTPM]":"3.1","Tissue RNA - colon [nTPM]":"6.3","Tissue RNA - duodenum [nTPM]":"2.9","Tissue RNA - endometrium 1 [nTPM]":"5.6","Tissue RNA - epididymis [nTPM]":"4.7","Tissue RNA - esophagus [nTPM]":"6.4","Tissue RNA - fallopian tube [nTPM]":"4.4","Tissue RNA - gallbladder [nTPM]":"6.0","Tissue RNA - heart muscle [nTPM]":"4.1","Tissue RNA - hippocampal formation [nTPM]":"2.7","Tissue RNA - hypothalamus [nTPM]":"3.6","Tissue RNA - kidney [nTPM]":"5.5","Tissue RNA - liver [nTPM]":"6.3","Tissue RNA - lung [nTPM]":"7.1","Tissue RNA - lymph node [nTPM]":"7.4","Tissue RNA - medulla oblongata [nTPM]":"5.2","Tissue RNA - midbrain [nTPM]":"3.7","Tissue RNA - ovary [nTPM]":"4.6","Tissue RNA - pancreas [nTPM]":"5.7","Tissue RNA - parathyroid gland [nTPM]":"2.5","Tissue RNA - pituitary gland [nTPM]":"5.2","Tissue RNA - placenta [nTPM]":"5.7","Tissue RNA - pons [nTPM]":"4.0","Tissue RNA - prostate [nTPM]":"4.2","Tissue RNA - rectum [nTPM]":"5.3","Tissue RNA - retina [nTPM]":"2.3","Tissue RNA - salivary gland [nTPM]":"10.0","Tissue RNA - seminal vesicle [nTPM]":"3.5","Tissue RNA - skeletal muscle [nTPM]":"4.8","Tissue RNA - skin 1 [nTPM]":"7.8","Tissue RNA - small intestine [nTPM]":"7.1","Tissue RNA - smooth muscle [nTPM]":"5.7","Tissue RNA - spinal cord [nTPM]":"6.5","Tissue RNA - spleen [nTPM]":"9.2","Tissue RNA - stomach 1 [nTPM]":"4.8","Tissue RNA - testis [nTPM]":"2.8","Tissue RNA - thalamus [nTPM]":"3.6","Tissue RNA - thymus [nTPM]":"15.6","Tissue RNA - thyroid gland [nTPM]":"4.3","Tissue RNA - tongue [nTPM]":"1.7","Tissue RNA - tonsil [nTPM]":"5.2","Tissue RNA - urinary bladder [nTPM]":"5.1","Tissue RNA - vagina [nTPM]":"5.3","Tissue RNA - white matter [nTPM]":"2.9","Cell RNA - A-431 [nTPM]":"4.3","Cell RNA - A549 [nTPM]":"2.4","Cell RNA - AF22 [nTPM]":"2.5","Cell RNA - AN3-CA [nTPM]":"2.2","Cell RNA - ASC diff [nTPM]":"7.5","Cell RNA - ASC TERT1 [nTPM]":"6.4","Cell RNA - BEWO [nTPM]":"2.7","Cell RNA - BJ [nTPM]":"2.1","Cell RNA - BJ hTERT+ [nTPM]":"14.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"79.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"76.0","Cell RNA - CACO-2 [nTPM]":"2.4","Cell RNA - CAPAN-2 [nTPM]":"1.4","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"2.7","Cell RNA - fHDF\/TERT166 [nTPM]":"2.7","Cell RNA - GAMG [nTPM]":"22.8","Cell RNA - HaCaT [nTPM]":"2.8","Cell RNA - HAP1 [nTPM]":"2.3","Cell RNA - HBEC3-KT [nTPM]":"1.3","Cell RNA - HBF TERT88 [nTPM]":"11.4","Cell RNA - HDLM-2 [nTPM]":"7.4","Cell RNA - HEK 293 [nTPM]":"0.9","Cell RNA - HEL [nTPM]":"1.1","Cell RNA - HeLa [nTPM]":"2.4","Cell RNA - Hep G2 [nTPM]":"3.5","Cell RNA - HHSteC [nTPM]":"5.0","Cell RNA - HL-60 [nTPM]":"1.4","Cell RNA - HMC-1 [nTPM]":"4.5","Cell RNA - HSkMC [nTPM]":"4.9","Cell RNA - hTCEpi [nTPM]":"1.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.9","Cell RNA - hTERT-HME1 [nTPM]":"1.3","Cell RNA - hTERT-RPE1 [nTPM]":"4.2","Cell RNA - HUVEC TERT2 [nTPM]":"14.3","Cell RNA - JURKAT [nTPM]":"1.5","Cell RNA - K-562 [nTPM]":"1.8","Cell RNA - Karpas-707 [nTPM]":"1.0","Cell RNA - LHCN-M2 [nTPM]":"6.6","Cell RNA - MCF7 [nTPM]":"0.6","Cell RNA - MOLT-4 [nTPM]":"3.8","Cell RNA - NB-4 [nTPM]":"12.4","Cell RNA - NTERA-2 [nTPM]":"1.8","Cell RNA - OE19 [nTPM]":"0.6","Cell RNA - PC-3 [nTPM]":"2.0","Cell RNA - REH [nTPM]":"2.4","Cell RNA - RH-30 [nTPM]":"3.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"11.6","Cell RNA - RT4 [nTPM]":"0.6","Cell RNA - SCLC-21H [nTPM]":"2.0","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"1.7","Cell RNA - SK-BR-3 [nTPM]":"1.7","Cell RNA - SK-MEL-30 [nTPM]":"12.6","Cell RNA - SuSa [nTPM]":"1.7","Cell RNA - T-47d [nTPM]":"3.5","Cell RNA - THP-1 [nTPM]":"0.9","Cell RNA - TIME [nTPM]":"13.4","Cell RNA - U-138 MG [nTPM]":"1.5","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"1.7","Cell RNA - U-251 MG [nTPM]":"1.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.9","Cell RNA - U-87 MG [nTPM]":"2.6","Cell RNA - U-937 [nTPM]":"3.3","Cell RNA - WM-115 [nTPM]":"2.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.5","Brain RNA - basal ganglia [nTPM]":"2.9","Brain RNA - cerebellum [nTPM]":"3.0","Brain RNA - cerebral cortex [nTPM]":"4.3","Brain RNA - hippocampal formation [nTPM]":"2.7","Brain RNA - hypothalamus [nTPM]":"3.6","Brain RNA - medulla oblongata [nTPM]":"5.2","Brain RNA - midbrain [nTPM]":"3.7","Brain RNA - pons [nTPM]":"4.0","Brain RNA - spinal cord [nTPM]":"6.5","Brain RNA - thalamus [nTPM]":"3.6","Brain RNA - white matter [nTPM]":"2.9","Single Cell Type RNA - Adipocytes [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.8","Single Cell Type RNA - Astrocytes [nTPM]":"20.5","Single Cell Type RNA - B-cells [nTPM]":"13.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"4.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"6.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.6","Single Cell Type RNA - dendritic cells [nTPM]":"13.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"19.5","Single Cell Type RNA - Early spermatids [nTPM]":"2.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.7","Single Cell Type RNA - Endothelial cells [nTPM]":"23.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.6","Single Cell Type RNA - Fibroblasts [nTPM]":"13.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.3","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"16.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.3","Single Cell Type RNA - Hepatocytes [nTPM]":"6.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.6","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.6","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"7.3","Single Cell Type RNA - Langerhans cells [nTPM]":"4.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.4","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"11.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"39.4","Single Cell Type RNA - monocytes [nTPM]":"12.3","Single Cell Type RNA - Muller glia cells [nTPM]":"6.4","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"31.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.2","Single Cell Type RNA - Paneth cells [nTPM]":"7.7","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"9.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"16.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"2.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - T-cells [nTPM]":"17.8","Single Cell Type RNA - Theca cells [nTPM]":"10.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.6","Single Cell Type RNA - Urothelial cells [nTPM]":"5.3"},{"Gene":"DDX59","Gene synonym":["DKFZP564B1023","ZNHIT5"],"Ensembl":"ENSG00000118197","Gene description":"DEAD-box helicase 59","Uniprot":["Q5T1V6"],"Chromosome":"1","Position":"200623896-200669907","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Helicase","Hydrolase","RNA-binding"],"Disease involvement":["Ciliopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047166"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":["Nucleoplasm","Actin filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA047166":"AB_2679966"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.02e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.4","Tissue RNA - adrenal gland [nTPM]":"16.1","Tissue RNA - amygdala [nTPM]":"13.5","Tissue RNA - appendix [nTPM]":"14.2","Tissue RNA - basal ganglia [nTPM]":"15.4","Tissue RNA - bone marrow [nTPM]":"33.1","Tissue RNA - breast [nTPM]":"26.5","Tissue RNA - cerebellum [nTPM]":"17.1","Tissue RNA - cerebral cortex [nTPM]":"18.8","Tissue RNA - cervix [nTPM]":"16.2","Tissue RNA - choroid plexus [nTPM]":"15.6","Tissue RNA - colon [nTPM]":"14.2","Tissue RNA - duodenum [nTPM]":"10.2","Tissue RNA - endometrium 1 [nTPM]":"17.6","Tissue RNA - epididymis [nTPM]":"20.0","Tissue RNA - esophagus [nTPM]":"13.5","Tissue RNA - fallopian tube [nTPM]":"15.5","Tissue RNA - gallbladder [nTPM]":"12.2","Tissue RNA - heart muscle [nTPM]":"13.3","Tissue RNA - hippocampal formation [nTPM]":"14.0","Tissue RNA - hypothalamus [nTPM]":"14.7","Tissue RNA - kidney [nTPM]":"16.4","Tissue RNA - liver [nTPM]":"17.8","Tissue RNA - lung [nTPM]":"14.5","Tissue RNA - lymph node [nTPM]":"17.0","Tissue RNA - medulla oblongata [nTPM]":"16.0","Tissue RNA - midbrain [nTPM]":"15.0","Tissue RNA - ovary [nTPM]":"17.6","Tissue RNA - pancreas [nTPM]":"18.8","Tissue RNA - parathyroid gland [nTPM]":"15.0","Tissue RNA - pituitary gland [nTPM]":"11.3","Tissue RNA - placenta [nTPM]":"18.7","Tissue RNA - pons [nTPM]":"17.3","Tissue RNA - prostate [nTPM]":"15.2","Tissue RNA - rectum [nTPM]":"15.0","Tissue RNA - retina [nTPM]":"17.4","Tissue RNA - salivary gland [nTPM]":"14.4","Tissue RNA - seminal vesicle [nTPM]":"13.2","Tissue RNA - skeletal muscle [nTPM]":"32.8","Tissue RNA - skin 1 [nTPM]":"26.2","Tissue RNA - small intestine [nTPM]":"14.3","Tissue RNA - smooth muscle [nTPM]":"14.1","Tissue RNA - spinal cord [nTPM]":"16.3","Tissue RNA - spleen [nTPM]":"22.4","Tissue RNA - stomach 1 [nTPM]":"12.1","Tissue RNA - testis [nTPM]":"11.0","Tissue RNA - thalamus [nTPM]":"15.1","Tissue RNA - thymus [nTPM]":"22.0","Tissue RNA - thyroid gland [nTPM]":"16.2","Tissue RNA - tongue [nTPM]":"20.1","Tissue RNA - tonsil [nTPM]":"16.9","Tissue RNA - urinary bladder [nTPM]":"15.0","Tissue RNA - vagina [nTPM]":"14.7","Tissue RNA - white matter [nTPM]":"17.8","Cell RNA - A-431 [nTPM]":"17.5","Cell RNA - A549 [nTPM]":"20.1","Cell RNA - AF22 [nTPM]":"22.6","Cell RNA - AN3-CA [nTPM]":"19.0","Cell RNA - ASC diff [nTPM]":"10.1","Cell RNA - ASC TERT1 [nTPM]":"17.4","Cell RNA - BEWO [nTPM]":"49.9","Cell RNA - BJ [nTPM]":"19.1","Cell RNA - BJ hTERT+ [nTPM]":"17.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.5","Cell RNA - CACO-2 [nTPM]":"6.3","Cell RNA - CAPAN-2 [nTPM]":"20.2","Cell RNA - Daudi [nTPM]":"17.9","Cell RNA - EFO-21 [nTPM]":"9.5","Cell RNA - fHDF\/TERT166 [nTPM]":"15.7","Cell RNA - GAMG [nTPM]":"16.4","Cell RNA - HaCaT [nTPM]":"16.2","Cell RNA - HAP1 [nTPM]":"13.0","Cell RNA - HBEC3-KT [nTPM]":"19.4","Cell RNA - HBF TERT88 [nTPM]":"14.5","Cell RNA - HDLM-2 [nTPM]":"56.8","Cell RNA - HEK 293 [nTPM]":"13.3","Cell RNA - HEL [nTPM]":"13.6","Cell RNA - HeLa [nTPM]":"26.4","Cell RNA - Hep G2 [nTPM]":"18.6","Cell RNA - HHSteC [nTPM]":"20.2","Cell RNA - HL-60 [nTPM]":"19.5","Cell RNA - HMC-1 [nTPM]":"24.0","Cell RNA - HSkMC [nTPM]":"18.8","Cell RNA - hTCEpi [nTPM]":"29.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.4","Cell RNA - hTERT-HME1 [nTPM]":"41.7","Cell RNA - hTERT-RPE1 [nTPM]":"16.7","Cell RNA - HUVEC TERT2 [nTPM]":"15.9","Cell RNA - JURKAT [nTPM]":"24.8","Cell RNA - K-562 [nTPM]":"17.4","Cell RNA - Karpas-707 [nTPM]":"25.9","Cell RNA - LHCN-M2 [nTPM]":"20.1","Cell RNA - MCF7 [nTPM]":"20.0","Cell RNA - MOLT-4 [nTPM]":"12.0","Cell RNA - NB-4 [nTPM]":"29.0","Cell RNA - NTERA-2 [nTPM]":"23.8","Cell RNA - OE19 [nTPM]":"10.5","Cell RNA - PC-3 [nTPM]":"16.3","Cell RNA - REH [nTPM]":"10.1","Cell RNA - RH-30 [nTPM]":"15.5","Cell RNA - RPMI-8226 [nTPM]":"34.7","Cell RNA - RPTEC TERT1 [nTPM]":"21.9","Cell RNA - RT4 [nTPM]":"19.8","Cell RNA - SCLC-21H [nTPM]":"13.8","Cell RNA - SH-SY5Y [nTPM]":"35.7","Cell RNA - SiHa [nTPM]":"30.8","Cell RNA - SK-BR-3 [nTPM]":"31.7","Cell RNA - SK-MEL-30 [nTPM]":"35.6","Cell RNA - SuSa [nTPM]":"28.8","Cell RNA - T-47d [nTPM]":"27.3","Cell RNA - THP-1 [nTPM]":"27.3","Cell RNA - TIME [nTPM]":"14.4","Cell RNA - U-138 MG [nTPM]":"17.1","Cell RNA - U-2 OS [nTPM]":"9.5","Cell RNA - U-2197 [nTPM]":"16.8","Cell RNA - U-251 MG [nTPM]":"20.0","Cell RNA - U-266\/70 [nTPM]":"19.5","Cell RNA - U-266\/84 [nTPM]":"27.2","Cell RNA - U-698 [nTPM]":"23.5","Cell RNA - U-87 MG [nTPM]":"16.3","Cell RNA - U-937 [nTPM]":"12.2","Cell RNA - WM-115 [nTPM]":"30.0","Blood RNA - basophil [nTPM]":"33.3","Blood RNA - classical monocyte [nTPM]":"12.4","Blood RNA - eosinophil [nTPM]":"24.7","Blood RNA - gdT-cell [nTPM]":"15.1","Blood RNA - intermediate monocyte [nTPM]":"11.1","Blood RNA - MAIT T-cell [nTPM]":"12.4","Blood RNA - memory B-cell [nTPM]":"14.9","Blood RNA - memory CD4 T-cell [nTPM]":"12.5","Blood RNA - memory CD8 T-cell [nTPM]":"13.8","Blood RNA - myeloid DC [nTPM]":"10.6","Blood RNA - naive B-cell [nTPM]":"14.8","Blood RNA - naive CD4 T-cell [nTPM]":"12.7","Blood RNA - naive CD8 T-cell [nTPM]":"11.8","Blood RNA - neutrophil [nTPM]":"22.9","Blood RNA - NK-cell [nTPM]":"16.4","Blood RNA - non-classical monocyte [nTPM]":"22.0","Blood RNA - plasmacytoid DC [nTPM]":"11.8","Blood RNA - T-reg [nTPM]":"19.8","Blood RNA - total PBMC [nTPM]":"10.2","Brain RNA - amygdala [nTPM]":"13.5","Brain RNA - basal ganglia [nTPM]":"15.4","Brain RNA - cerebellum [nTPM]":"17.1","Brain RNA - cerebral cortex [nTPM]":"18.8","Brain RNA - hippocampal formation [nTPM]":"14.0","Brain RNA - hypothalamus [nTPM]":"14.7","Brain RNA - medulla oblongata [nTPM]":"16.0","Brain RNA - midbrain [nTPM]":"15.0","Brain RNA - pons [nTPM]":"17.3","Brain RNA - spinal cord [nTPM]":"16.3","Brain RNA - thalamus [nTPM]":"15.1","Brain RNA - white matter [nTPM]":"17.8","Single Cell Type RNA - Adipocytes [nTPM]":"22.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.1","Single Cell Type RNA - Astrocytes [nTPM]":"8.8","Single Cell Type RNA - B-cells [nTPM]":"19.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"4.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"10.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"22.2","Single Cell Type RNA - dendritic cells [nTPM]":"14.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"8.8","Single Cell Type RNA - Early spermatids [nTPM]":"2.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.3","Single Cell Type RNA - Endothelial cells [nTPM]":"16.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"10.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"28.0","Single Cell Type RNA - Fibroblasts [nTPM]":"14.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.8","Single Cell Type RNA - granulocytes [nTPM]":"20.8","Single Cell Type RNA - Granulosa cells [nTPM]":"7.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.3","Single Cell Type RNA - Hepatocytes [nTPM]":"7.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.0","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.0","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"12.0","Single Cell Type RNA - Langerhans cells [nTPM]":"13.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.1","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"16.1","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"18.5","Single Cell Type RNA - Muller glia cells [nTPM]":"8.3","Single Cell Type RNA - NK-cells [nTPM]":"25.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.8","Single Cell Type RNA - Paneth cells [nTPM]":"7.9","Single Cell Type RNA - Peritubular cells [nTPM]":"13.5","Single Cell Type RNA - Plasma cells [nTPM]":"13.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.7","Single Cell Type RNA - Spermatocytes [nTPM]":"14.2","Single Cell Type RNA - Spermatogonia [nTPM]":"20.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"43.8","Single Cell Type RNA - T-cells [nTPM]":"18.9","Single Cell Type RNA - Theca cells [nTPM]":"9.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.5","Single Cell Type RNA - Urothelial cells [nTPM]":"11.1"},{"Gene":"DDX6","Gene synonym":["HLR2","RCK","Rck\/p54"],"Ensembl":"ENSG00000110367","Gene description":"DEAD-box helicase 6","Uniprot":["P26196"],"Chromosome":"11","Position":"118747763-118791164","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Helicase","Hydrolase","RNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004668","HPA024201","HPA026644"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol","Cytoplasmic bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"19000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Cytoplasmic bodies"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB004668":"AB_436960","HPA024201":"AB_10603562","HPA026644":"AB_1847582"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.56e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-2"},"Tissue RNA - adipose tissue [nTPM]":"31.5","Tissue RNA - adrenal gland [nTPM]":"28.4","Tissue RNA - amygdala [nTPM]":"29.1","Tissue RNA - appendix [nTPM]":"34.9","Tissue RNA - basal ganglia [nTPM]":"36.0","Tissue RNA - bone marrow [nTPM]":"69.0","Tissue RNA - breast [nTPM]":"34.9","Tissue RNA - cerebellum [nTPM]":"50.7","Tissue RNA - cerebral cortex [nTPM]":"31.9","Tissue RNA - cervix [nTPM]":"33.2","Tissue RNA - choroid plexus [nTPM]":"12.7","Tissue RNA - colon [nTPM]":"30.0","Tissue RNA - duodenum [nTPM]":"23.7","Tissue RNA - endometrium 1 [nTPM]":"30.5","Tissue RNA - epididymis [nTPM]":"30.5","Tissue RNA - esophagus [nTPM]":"33.1","Tissue RNA - fallopian tube [nTPM]":"29.1","Tissue RNA - gallbladder [nTPM]":"23.6","Tissue RNA - heart muscle [nTPM]":"37.2","Tissue RNA - hippocampal formation [nTPM]":"31.5","Tissue RNA - hypothalamus [nTPM]":"35.4","Tissue RNA - kidney [nTPM]":"30.6","Tissue RNA - liver [nTPM]":"34.2","Tissue RNA - lung [nTPM]":"27.3","Tissue RNA - lymph node [nTPM]":"49.0","Tissue RNA - medulla oblongata [nTPM]":"28.4","Tissue RNA - midbrain [nTPM]":"29.3","Tissue RNA - ovary [nTPM]":"48.8","Tissue RNA - pancreas [nTPM]":"30.7","Tissue RNA - parathyroid gland [nTPM]":"28.3","Tissue RNA - pituitary gland [nTPM]":"17.3","Tissue RNA - placenta [nTPM]":"31.6","Tissue RNA - pons [nTPM]":"25.2","Tissue RNA - prostate [nTPM]":"32.9","Tissue RNA - rectum [nTPM]":"27.9","Tissue RNA - retina [nTPM]":"48.7","Tissue RNA - salivary gland [nTPM]":"32.4","Tissue RNA - seminal vesicle [nTPM]":"29.2","Tissue RNA - skeletal muscle [nTPM]":"43.2","Tissue RNA - skin 1 [nTPM]":"27.2","Tissue RNA - small intestine [nTPM]":"26.2","Tissue RNA - smooth muscle [nTPM]":"30.6","Tissue RNA - spinal cord [nTPM]":"29.9","Tissue RNA - spleen [nTPM]":"45.4","Tissue RNA - stomach 1 [nTPM]":"29.9","Tissue RNA - testis [nTPM]":"28.8","Tissue RNA - thalamus [nTPM]":"37.1","Tissue RNA - thymus [nTPM]":"54.9","Tissue RNA - thyroid gland [nTPM]":"37.5","Tissue RNA - tongue [nTPM]":"41.9","Tissue RNA - tonsil [nTPM]":"60.9","Tissue RNA - urinary bladder [nTPM]":"30.0","Tissue RNA - vagina [nTPM]":"21.9","Tissue RNA - white matter [nTPM]":"36.6","Cell RNA - A-431 [nTPM]":"33.9","Cell RNA - A549 [nTPM]":"50.4","Cell RNA - AF22 [nTPM]":"73.6","Cell RNA - AN3-CA [nTPM]":"71.7","Cell RNA - ASC diff [nTPM]":"64.0","Cell RNA - ASC TERT1 [nTPM]":"64.8","Cell RNA - BEWO [nTPM]":"47.2","Cell RNA - BJ [nTPM]":"45.6","Cell RNA - BJ hTERT+ [nTPM]":"62.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"43.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"40.4","Cell RNA - CACO-2 [nTPM]":"72.1","Cell RNA - CAPAN-2 [nTPM]":"50.9","Cell RNA - Daudi [nTPM]":"77.6","Cell RNA - EFO-21 [nTPM]":"47.1","Cell RNA - fHDF\/TERT166 [nTPM]":"78.8","Cell RNA - GAMG [nTPM]":"44.3","Cell RNA - HaCaT [nTPM]":"53.2","Cell RNA - HAP1 [nTPM]":"88.8","Cell RNA - HBEC3-KT [nTPM]":"69.1","Cell RNA - HBF TERT88 [nTPM]":"69.0","Cell RNA - HDLM-2 [nTPM]":"62.7","Cell RNA - HEK 293 [nTPM]":"17.4","Cell RNA - HEL [nTPM]":"154.5","Cell RNA - HeLa [nTPM]":"30.8","Cell RNA - Hep G2 [nTPM]":"57.1","Cell RNA - HHSteC [nTPM]":"42.0","Cell RNA - HL-60 [nTPM]":"110.9","Cell RNA - HMC-1 [nTPM]":"55.8","Cell RNA - HSkMC [nTPM]":"67.1","Cell RNA - hTCEpi [nTPM]":"49.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"63.5","Cell RNA - hTERT-HME1 [nTPM]":"100.8","Cell RNA - hTERT-RPE1 [nTPM]":"54.8","Cell RNA - HUVEC TERT2 [nTPM]":"69.1","Cell RNA - JURKAT [nTPM]":"53.2","Cell RNA - K-562 [nTPM]":"72.5","Cell RNA - Karpas-707 [nTPM]":"110.4","Cell RNA - LHCN-M2 [nTPM]":"59.2","Cell RNA - MCF7 [nTPM]":"96.8","Cell RNA - MOLT-4 [nTPM]":"81.0","Cell RNA - NB-4 [nTPM]":"52.1","Cell RNA - NTERA-2 [nTPM]":"53.3","Cell RNA - OE19 [nTPM]":"50.1","Cell RNA - PC-3 [nTPM]":"33.6","Cell RNA - REH [nTPM]":"89.3","Cell RNA - RH-30 [nTPM]":"59.2","Cell RNA - RPMI-8226 [nTPM]":"60.1","Cell RNA - RPTEC TERT1 [nTPM]":"50.1","Cell RNA - RT4 [nTPM]":"92.7","Cell RNA - SCLC-21H [nTPM]":"48.7","Cell RNA - SH-SY5Y [nTPM]":"63.9","Cell RNA - SiHa [nTPM]":"84.7","Cell RNA - SK-BR-3 [nTPM]":"67.2","Cell RNA - SK-MEL-30 [nTPM]":"28.5","Cell RNA - SuSa [nTPM]":"56.2","Cell RNA - T-47d [nTPM]":"79.2","Cell RNA - THP-1 [nTPM]":"44.2","Cell RNA - TIME [nTPM]":"81.2","Cell RNA - U-138 MG [nTPM]":"67.2","Cell RNA - U-2 OS [nTPM]":"38.4","Cell RNA - U-2197 [nTPM]":"39.8","Cell RNA - U-251 MG [nTPM]":"47.6","Cell RNA - U-266\/70 [nTPM]":"34.1","Cell RNA - U-266\/84 [nTPM]":"47.8","Cell RNA - U-698 [nTPM]":"91.7","Cell RNA - U-87 MG [nTPM]":"26.8","Cell RNA - U-937 [nTPM]":"52.2","Cell RNA - WM-115 [nTPM]":"59.2","Blood RNA - basophil [nTPM]":"13.8","Blood RNA - classical monocyte [nTPM]":"4.8","Blood RNA - eosinophil [nTPM]":"13.2","Blood RNA - gdT-cell [nTPM]":"10.2","Blood RNA - intermediate monocyte [nTPM]":"6.2","Blood RNA - MAIT T-cell [nTPM]":"12.3","Blood RNA - memory B-cell [nTPM]":"12.1","Blood RNA - memory CD4 T-cell [nTPM]":"10.0","Blood RNA - memory CD8 T-cell [nTPM]":"10.8","Blood RNA - myeloid DC [nTPM]":"5.1","Blood RNA - naive B-cell [nTPM]":"12.0","Blood RNA - naive CD4 T-cell [nTPM]":"12.2","Blood RNA - naive CD8 T-cell [nTPM]":"11.0","Blood RNA - neutrophil [nTPM]":"19.0","Blood RNA - NK-cell [nTPM]":"8.3","Blood RNA - non-classical monocyte [nTPM]":"12.4","Blood RNA - plasmacytoid DC [nTPM]":"7.1","Blood RNA - T-reg [nTPM]":"9.9","Blood RNA - total PBMC [nTPM]":"6.8","Brain RNA - amygdala [nTPM]":"29.1","Brain RNA - basal ganglia [nTPM]":"36.0","Brain RNA - cerebellum [nTPM]":"50.7","Brain RNA - cerebral cortex [nTPM]":"31.9","Brain RNA - hippocampal formation [nTPM]":"31.5","Brain RNA - hypothalamus [nTPM]":"35.4","Brain RNA - medulla oblongata [nTPM]":"28.4","Brain RNA - midbrain [nTPM]":"29.3","Brain RNA - pons [nTPM]":"25.2","Brain RNA - spinal cord [nTPM]":"29.9","Brain RNA - thalamus [nTPM]":"37.1","Brain RNA - white matter [nTPM]":"36.6","Single Cell Type RNA - Adipocytes [nTPM]":"84.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"57.9","Single Cell Type RNA - Astrocytes [nTPM]":"37.9","Single Cell Type RNA - B-cells [nTPM]":"140.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"75.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"31.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"69.4","Single Cell Type RNA - Bipolar cells [nTPM]":"82.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"49.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"43.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"116.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"42.9","Single Cell Type RNA - Club cells [nTPM]":"41.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"50.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"38.4","Single Cell Type RNA - dendritic cells [nTPM]":"184.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"58.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"31.3","Single Cell Type RNA - Ductal cells [nTPM]":"32.2","Single Cell Type RNA - Early spermatids [nTPM]":"4.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"77.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"81.5","Single Cell Type RNA - Endothelial cells [nTPM]":"64.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"85.7","Single Cell Type RNA - Erythroid cells [nTPM]":"88.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"57.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"35.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"36.5","Single Cell Type RNA - Fibroblasts [nTPM]":"55.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"42.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"91.7","Single Cell Type RNA - granulocytes [nTPM]":"52.5","Single Cell Type RNA - Granulosa cells [nTPM]":"54.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"61.8","Single Cell Type RNA - Hepatocytes [nTPM]":"41.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"38.3","Single Cell Type RNA - Horizontal cells [nTPM]":"62.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"60.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"59.8","Single Cell Type RNA - Ionocytes [nTPM]":"42.7","Single Cell Type RNA - Kupffer cells [nTPM]":"66.9","Single Cell Type RNA - Langerhans cells [nTPM]":"44.3","Single Cell Type RNA - Late spermatids [nTPM]":"10.5","Single Cell Type RNA - Leydig cells [nTPM]":"54.0","Single Cell Type RNA - Macrophages [nTPM]":"70.1","Single Cell Type RNA - Melanocytes [nTPM]":"33.8","Single Cell Type RNA - Microglial cells [nTPM]":"68.4","Single Cell Type RNA - monocytes [nTPM]":"75.9","Single Cell Type RNA - Muller glia cells [nTPM]":"90.0","Single Cell Type RNA - NK-cells [nTPM]":"119.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"50.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"80.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"51.2","Single Cell Type RNA - Paneth cells [nTPM]":"57.0","Single Cell Type RNA - Peritubular cells [nTPM]":"45.1","Single Cell Type RNA - Plasma cells [nTPM]":"106.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"49.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"57.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"41.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"35.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"91.3","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"92.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"69.7","Single Cell Type RNA - Spermatocytes [nTPM]":"71.1","Single Cell Type RNA - Spermatogonia [nTPM]":"76.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"73.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"30.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"76.5","Single Cell Type RNA - T-cells [nTPM]":"130.2","Single Cell Type RNA - Theca cells [nTPM]":"48.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"53.1","Single Cell Type RNA - Urothelial cells [nTPM]":"78.2"},{"Gene":"DECR1","Gene synonym":["DECR","SDR18C1"],"Ensembl":"ENSG00000104325","Gene description":"2,4-dienoyl-CoA reductase 1","Uniprot":["Q16698"],"Chromosome":"8","Position":"90001405-90053633","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"290.1","liver":"272.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"399.2","Proximal tubular cells":"485.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SK-BR-3":"81.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023160","HPA023162","HPA023238"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"120000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA023160":"AB_1847585","HPA023162":"AB_1847586","HPA023238":"AB_1847587"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.49e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.79e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.06e-4"},"Tissue RNA - adipose tissue [nTPM]":"60.2","Tissue RNA - adrenal gland [nTPM]":"136.8","Tissue RNA - amygdala [nTPM]":"12.4","Tissue RNA - appendix [nTPM]":"9.6","Tissue RNA - basal ganglia [nTPM]":"14.4","Tissue RNA - bone marrow [nTPM]":"24.9","Tissue RNA - breast [nTPM]":"54.4","Tissue RNA - cerebellum [nTPM]":"12.5","Tissue RNA - cerebral cortex [nTPM]":"14.4","Tissue RNA - cervix [nTPM]":"29.4","Tissue RNA - choroid plexus [nTPM]":"22.2","Tissue RNA - colon [nTPM]":"65.0","Tissue RNA - duodenum [nTPM]":"20.2","Tissue RNA - endometrium 1 [nTPM]":"28.0","Tissue RNA - epididymis [nTPM]":"14.9","Tissue RNA - esophagus [nTPM]":"52.6","Tissue RNA - fallopian tube [nTPM]":"26.1","Tissue RNA - gallbladder [nTPM]":"7.4","Tissue RNA - heart muscle [nTPM]":"290.1","Tissue RNA - hippocampal formation [nTPM]":"12.7","Tissue RNA - hypothalamus [nTPM]":"13.2","Tissue RNA - kidney [nTPM]":"103.5","Tissue RNA - liver [nTPM]":"272.3","Tissue RNA - lung [nTPM]":"34.2","Tissue RNA - lymph node [nTPM]":"15.0","Tissue RNA - medulla oblongata [nTPM]":"12.2","Tissue RNA - midbrain [nTPM]":"13.1","Tissue RNA - ovary [nTPM]":"35.5","Tissue RNA - pancreas [nTPM]":"44.4","Tissue RNA - parathyroid gland [nTPM]":"13.2","Tissue RNA - pituitary gland [nTPM]":"32.6","Tissue RNA - placenta [nTPM]":"5.9","Tissue RNA - pons [nTPM]":"12.1","Tissue RNA - prostate [nTPM]":"28.6","Tissue RNA - rectum [nTPM]":"18.8","Tissue RNA - retina [nTPM]":"8.0","Tissue RNA - salivary gland [nTPM]":"42.8","Tissue RNA - seminal vesicle [nTPM]":"6.5","Tissue RNA - skeletal muscle [nTPM]":"121.8","Tissue RNA - skin 1 [nTPM]":"43.3","Tissue RNA - small intestine [nTPM]":"61.0","Tissue RNA - smooth muscle [nTPM]":"9.1","Tissue RNA - spinal cord [nTPM]":"12.5","Tissue RNA - spleen [nTPM]":"47.1","Tissue RNA - stomach 1 [nTPM]":"44.5","Tissue RNA - testis [nTPM]":"52.3","Tissue RNA - thalamus [nTPM]":"15.4","Tissue RNA - thymus [nTPM]":"10.2","Tissue RNA - thyroid gland [nTPM]":"33.0","Tissue RNA - tongue [nTPM]":"34.4","Tissue RNA - tonsil [nTPM]":"13.9","Tissue RNA - urinary bladder [nTPM]":"31.1","Tissue RNA - vagina [nTPM]":"35.8","Tissue RNA - white matter [nTPM]":"12.8","Cell RNA - A-431 [nTPM]":"13.1","Cell RNA - A549 [nTPM]":"7.9","Cell RNA - AF22 [nTPM]":"19.6","Cell RNA - AN3-CA [nTPM]":"16.1","Cell RNA - ASC diff [nTPM]":"8.0","Cell RNA - ASC TERT1 [nTPM]":"17.3","Cell RNA - BEWO [nTPM]":"5.2","Cell RNA - BJ [nTPM]":"13.2","Cell RNA - BJ hTERT+ [nTPM]":"12.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.2","Cell RNA - CACO-2 [nTPM]":"2.8","Cell RNA - CAPAN-2 [nTPM]":"13.4","Cell RNA - Daudi [nTPM]":"7.7","Cell RNA - EFO-21 [nTPM]":"5.3","Cell RNA - fHDF\/TERT166 [nTPM]":"15.1","Cell RNA - GAMG [nTPM]":"4.1","Cell RNA - HaCaT [nTPM]":"6.8","Cell RNA - HAP1 [nTPM]":"7.7","Cell RNA - HBEC3-KT [nTPM]":"11.1","Cell RNA - HBF TERT88 [nTPM]":"11.0","Cell RNA - HDLM-2 [nTPM]":"12.6","Cell RNA - HEK 293 [nTPM]":"1.2","Cell RNA - HEL [nTPM]":"18.4","Cell RNA - HeLa [nTPM]":"13.6","Cell RNA - Hep G2 [nTPM]":"14.5","Cell RNA - HHSteC [nTPM]":"11.6","Cell RNA - HL-60 [nTPM]":"8.7","Cell RNA - HMC-1 [nTPM]":"4.4","Cell RNA - HSkMC [nTPM]":"12.0","Cell RNA - hTCEpi [nTPM]":"7.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.6","Cell RNA - hTERT-HME1 [nTPM]":"10.7","Cell RNA - hTERT-RPE1 [nTPM]":"10.1","Cell RNA - HUVEC TERT2 [nTPM]":"17.4","Cell RNA - JURKAT [nTPM]":"16.5","Cell RNA - K-562 [nTPM]":"21.3","Cell RNA - Karpas-707 [nTPM]":"15.5","Cell RNA - LHCN-M2 [nTPM]":"20.7","Cell RNA - MCF7 [nTPM]":"16.3","Cell RNA - MOLT-4 [nTPM]":"12.5","Cell RNA - NB-4 [nTPM]":"7.6","Cell RNA - NTERA-2 [nTPM]":"1.5","Cell RNA - OE19 [nTPM]":"9.1","Cell RNA - PC-3 [nTPM]":"24.9","Cell RNA - REH [nTPM]":"7.4","Cell RNA - RH-30 [nTPM]":"5.8","Cell RNA - RPMI-8226 [nTPM]":"13.4","Cell RNA - RPTEC TERT1 [nTPM]":"23.4","Cell RNA - RT4 [nTPM]":"43.9","Cell RNA - SCLC-21H [nTPM]":"1.3","Cell RNA - SH-SY5Y [nTPM]":"10.6","Cell RNA - SiHa [nTPM]":"13.0","Cell RNA - SK-BR-3 [nTPM]":"81.1","Cell RNA - SK-MEL-30 [nTPM]":"7.7","Cell RNA - SuSa [nTPM]":"1.1","Cell RNA - T-47d [nTPM]":"10.7","Cell RNA - THP-1 [nTPM]":"7.4","Cell RNA - TIME [nTPM]":"20.1","Cell RNA - U-138 MG [nTPM]":"11.4","Cell RNA - U-2 OS [nTPM]":"6.2","Cell RNA - U-2197 [nTPM]":"12.9","Cell RNA - U-251 MG [nTPM]":"6.0","Cell RNA - U-266\/70 [nTPM]":"10.5","Cell RNA - U-266\/84 [nTPM]":"7.5","Cell RNA - U-698 [nTPM]":"12.8","Cell RNA - U-87 MG [nTPM]":"8.6","Cell RNA - U-937 [nTPM]":"12.0","Cell RNA - WM-115 [nTPM]":"10.8","Blood RNA - basophil [nTPM]":"3.9","Blood RNA - classical monocyte [nTPM]":"9.1","Blood RNA - eosinophil [nTPM]":"6.2","Blood RNA - gdT-cell [nTPM]":"7.1","Blood RNA - intermediate monocyte [nTPM]":"10.2","Blood RNA - MAIT T-cell [nTPM]":"7.9","Blood RNA - memory B-cell [nTPM]":"7.4","Blood RNA - memory CD4 T-cell [nTPM]":"6.9","Blood RNA - memory CD8 T-cell [nTPM]":"8.6","Blood RNA - myeloid DC [nTPM]":"8.8","Blood RNA - naive B-cell [nTPM]":"4.6","Blood RNA - naive CD4 T-cell [nTPM]":"8.1","Blood RNA - naive CD8 T-cell [nTPM]":"7.8","Blood RNA - neutrophil [nTPM]":"15.2","Blood RNA - NK-cell [nTPM]":"3.9","Blood RNA - non-classical monocyte [nTPM]":"9.3","Blood RNA - plasmacytoid DC [nTPM]":"3.9","Blood RNA - T-reg [nTPM]":"9.6","Blood RNA - total PBMC [nTPM]":"5.8","Brain RNA - amygdala [nTPM]":"12.4","Brain RNA - basal ganglia [nTPM]":"14.4","Brain RNA - cerebellum [nTPM]":"12.5","Brain RNA - cerebral cortex [nTPM]":"14.4","Brain RNA - hippocampal formation [nTPM]":"12.7","Brain RNA - hypothalamus [nTPM]":"13.2","Brain RNA - medulla oblongata [nTPM]":"12.2","Brain RNA - midbrain [nTPM]":"13.1","Brain RNA - pons [nTPM]":"12.1","Brain RNA - spinal cord [nTPM]":"12.5","Brain RNA - thalamus [nTPM]":"15.4","Brain RNA - white matter [nTPM]":"12.8","Single Cell Type RNA - Adipocytes [nTPM]":"66.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"76.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"59.4","Single Cell Type RNA - Astrocytes [nTPM]":"72.5","Single Cell Type RNA - B-cells [nTPM]":"52.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"41.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"70.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"180.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"35.3","Single Cell Type RNA - Bipolar cells [nTPM]":"11.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"51.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"57.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"268.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"82.9","Single Cell Type RNA - Club cells [nTPM]":"96.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"71.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"50.2","Single Cell Type RNA - dendritic cells [nTPM]":"57.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"119.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"399.2","Single Cell Type RNA - Ductal cells [nTPM]":"137.8","Single Cell Type RNA - Early spermatids [nTPM]":"165.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"68.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"65.5","Single Cell Type RNA - Endothelial cells [nTPM]":"60.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"104.8","Single Cell Type RNA - Erythroid cells [nTPM]":"77.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"27.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"92.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"49.0","Single Cell Type RNA - Fibroblasts [nTPM]":"60.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"61.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"40.6","Single Cell Type RNA - granulocytes [nTPM]":"50.0","Single Cell Type RNA - Granulosa cells [nTPM]":"81.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"47.8","Single Cell Type RNA - Hepatocytes [nTPM]":"244.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"115.1","Single Cell Type RNA - Horizontal cells [nTPM]":"32.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"55.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"105.9","Single Cell Type RNA - Ionocytes [nTPM]":"116.0","Single Cell Type RNA - Kupffer cells [nTPM]":"95.2","Single Cell Type RNA - Langerhans cells [nTPM]":"82.7","Single Cell Type RNA - Late spermatids [nTPM]":"52.6","Single Cell Type RNA - Leydig cells [nTPM]":"85.4","Single Cell Type RNA - Macrophages [nTPM]":"85.1","Single Cell Type RNA - Melanocytes [nTPM]":"85.4","Single Cell Type RNA - Microglial cells [nTPM]":"29.0","Single Cell Type RNA - monocytes [nTPM]":"107.1","Single Cell Type RNA - Muller glia cells [nTPM]":"52.5","Single Cell Type RNA - NK-cells [nTPM]":"74.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"66.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"35.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"87.5","Single Cell Type RNA - Paneth cells [nTPM]":"111.6","Single Cell Type RNA - Peritubular cells [nTPM]":"51.6","Single Cell Type RNA - Plasma cells [nTPM]":"67.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"250.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"485.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"69.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.6","Single Cell Type RNA - Sertoli cells [nTPM]":"72.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"54.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"61.7","Single Cell Type RNA - Spermatocytes [nTPM]":"157.5","Single Cell Type RNA - Spermatogonia [nTPM]":"24.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"68.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"41.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"41.0","Single Cell Type RNA - T-cells [nTPM]":"64.4","Single Cell Type RNA - Theca cells [nTPM]":"135.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"139.6","Single Cell Type RNA - Urothelial cells [nTPM]":"86.8"},{"Gene":"DEGS1","Gene synonym":["DEGS-1","Des-1","DES1","FADS7","MLD"],"Ensembl":"ENSG00000143753","Gene description":"Delta 4-desaturase, sphingolipid 1","Uniprot":["O15121"],"Chromosome":"1","Position":"224175756-224193441","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Leukodystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"skin 1":"535.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"246.0","Cytotrophoblasts":"281.8","Suprabasal keratinocytes":"320.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA076422"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA076422":"AB_2686799"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.74e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.29e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.83e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.53e-4"},"Tissue RNA - adipose tissue [nTPM]":"60.3","Tissue RNA - adrenal gland [nTPM]":"31.0","Tissue RNA - amygdala [nTPM]":"30.3","Tissue RNA - appendix [nTPM]":"44.9","Tissue RNA - basal ganglia [nTPM]":"33.1","Tissue RNA - bone marrow [nTPM]":"69.5","Tissue RNA - breast [nTPM]":"61.9","Tissue RNA - cerebellum [nTPM]":"35.0","Tissue RNA - cerebral cortex [nTPM]":"36.2","Tissue RNA - cervix [nTPM]":"53.4","Tissue RNA - choroid plexus [nTPM]":"42.5","Tissue RNA - colon [nTPM]":"50.8","Tissue RNA - duodenum [nTPM]":"47.0","Tissue RNA - endometrium 1 [nTPM]":"44.5","Tissue RNA - epididymis [nTPM]":"29.5","Tissue RNA - esophagus [nTPM]":"48.6","Tissue RNA - fallopian tube [nTPM]":"34.4","Tissue RNA - gallbladder [nTPM]":"40.5","Tissue RNA - heart muscle [nTPM]":"43.8","Tissue RNA - hippocampal formation [nTPM]":"31.3","Tissue RNA - hypothalamus [nTPM]":"35.6","Tissue RNA - kidney [nTPM]":"38.1","Tissue RNA - liver [nTPM]":"35.7","Tissue RNA - lung [nTPM]":"49.1","Tissue RNA - lymph node [nTPM]":"48.0","Tissue RNA - medulla oblongata [nTPM]":"36.6","Tissue RNA - midbrain [nTPM]":"35.2","Tissue RNA - ovary [nTPM]":"27.1","Tissue RNA - pancreas [nTPM]":"22.5","Tissue RNA - parathyroid gland [nTPM]":"31.5","Tissue RNA - pituitary gland [nTPM]":"34.8","Tissue RNA - placenta [nTPM]":"128.7","Tissue RNA - pons [nTPM]":"35.9","Tissue RNA - prostate [nTPM]":"83.2","Tissue RNA - rectum [nTPM]":"27.2","Tissue RNA - retina [nTPM]":"20.8","Tissue RNA - salivary gland [nTPM]":"38.7","Tissue RNA - seminal vesicle [nTPM]":"58.6","Tissue RNA - skeletal muscle [nTPM]":"20.9","Tissue RNA - skin 1 [nTPM]":"535.6","Tissue RNA - small intestine [nTPM]":"33.4","Tissue RNA - smooth muscle [nTPM]":"70.9","Tissue RNA - spinal cord [nTPM]":"37.9","Tissue RNA - spleen [nTPM]":"38.7","Tissue RNA - stomach 1 [nTPM]":"38.6","Tissue RNA - testis [nTPM]":"22.7","Tissue RNA - thalamus [nTPM]":"34.0","Tissue RNA - thymus [nTPM]":"34.2","Tissue RNA - thyroid gland [nTPM]":"52.3","Tissue RNA - tongue [nTPM]":"23.3","Tissue RNA - tonsil [nTPM]":"50.9","Tissue RNA - urinary bladder [nTPM]":"48.4","Tissue RNA - vagina [nTPM]":"72.7","Tissue RNA - white matter [nTPM]":"44.5","Cell RNA - A-431 [nTPM]":"72.8","Cell RNA - A549 [nTPM]":"50.7","Cell RNA - AF22 [nTPM]":"65.2","Cell RNA - AN3-CA [nTPM]":"49.5","Cell RNA - ASC diff [nTPM]":"275.7","Cell RNA - ASC TERT1 [nTPM]":"181.1","Cell RNA - BEWO [nTPM]":"51.2","Cell RNA - BJ [nTPM]":"201.1","Cell RNA - BJ hTERT+ [nTPM]":"223.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"137.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"164.2","Cell RNA - CACO-2 [nTPM]":"47.1","Cell RNA - CAPAN-2 [nTPM]":"55.2","Cell RNA - Daudi [nTPM]":"58.0","Cell RNA - EFO-21 [nTPM]":"252.4","Cell RNA - fHDF\/TERT166 [nTPM]":"181.0","Cell RNA - GAMG [nTPM]":"82.4","Cell RNA - HaCaT [nTPM]":"76.3","Cell RNA - HAP1 [nTPM]":"76.5","Cell RNA - HBEC3-KT [nTPM]":"67.9","Cell RNA - HBF TERT88 [nTPM]":"153.0","Cell RNA - HDLM-2 [nTPM]":"84.2","Cell RNA - HEK 293 [nTPM]":"141.5","Cell RNA - HEL [nTPM]":"41.7","Cell RNA - HeLa [nTPM]":"51.1","Cell RNA - Hep G2 [nTPM]":"29.2","Cell RNA - HHSteC [nTPM]":"167.9","Cell RNA - HL-60 [nTPM]":"84.2","Cell RNA - HMC-1 [nTPM]":"86.1","Cell RNA - HSkMC [nTPM]":"177.4","Cell RNA - hTCEpi [nTPM]":"153.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"125.5","Cell RNA - hTERT-HME1 [nTPM]":"69.9","Cell RNA - hTERT-RPE1 [nTPM]":"143.0","Cell RNA - HUVEC TERT2 [nTPM]":"140.4","Cell RNA - JURKAT [nTPM]":"31.4","Cell RNA - K-562 [nTPM]":"62.8","Cell RNA - Karpas-707 [nTPM]":"61.8","Cell RNA - LHCN-M2 [nTPM]":"181.2","Cell RNA - MCF7 [nTPM]":"27.5","Cell RNA - MOLT-4 [nTPM]":"43.2","Cell RNA - NB-4 [nTPM]":"46.9","Cell RNA - NTERA-2 [nTPM]":"83.3","Cell RNA - OE19 [nTPM]":"40.0","Cell RNA - PC-3 [nTPM]":"76.1","Cell RNA - REH [nTPM]":"38.8","Cell RNA - RH-30 [nTPM]":"92.4","Cell RNA - RPMI-8226 [nTPM]":"37.5","Cell RNA - RPTEC TERT1 [nTPM]":"181.1","Cell RNA - RT4 [nTPM]":"19.8","Cell RNA - SCLC-21H [nTPM]":"42.3","Cell RNA - SH-SY5Y [nTPM]":"69.8","Cell RNA - SiHa [nTPM]":"106.6","Cell RNA - SK-BR-3 [nTPM]":"169.4","Cell RNA - SK-MEL-30 [nTPM]":"110.4","Cell RNA - SuSa [nTPM]":"118.8","Cell RNA - T-47d [nTPM]":"57.1","Cell RNA - THP-1 [nTPM]":"123.4","Cell RNA - TIME [nTPM]":"125.7","Cell RNA - U-138 MG [nTPM]":"133.4","Cell RNA - U-2 OS [nTPM]":"41.4","Cell RNA - U-2197 [nTPM]":"153.1","Cell RNA - U-251 MG [nTPM]":"197.5","Cell RNA - U-266\/70 [nTPM]":"44.5","Cell RNA - U-266\/84 [nTPM]":"55.3","Cell RNA - U-698 [nTPM]":"52.8","Cell RNA - U-87 MG [nTPM]":"141.9","Cell RNA - U-937 [nTPM]":"41.7","Cell RNA - WM-115 [nTPM]":"154.2","Blood RNA - basophil [nTPM]":"104.6","Blood RNA - classical monocyte [nTPM]":"61.4","Blood RNA - eosinophil [nTPM]":"120.3","Blood RNA - gdT-cell [nTPM]":"30.9","Blood RNA - intermediate monocyte [nTPM]":"67.8","Blood RNA - MAIT T-cell [nTPM]":"59.8","Blood RNA - memory B-cell [nTPM]":"58.2","Blood RNA - memory CD4 T-cell [nTPM]":"52.7","Blood RNA - memory CD8 T-cell [nTPM]":"43.3","Blood RNA - myeloid DC [nTPM]":"104.4","Blood RNA - naive B-cell [nTPM]":"74.3","Blood RNA - naive CD4 T-cell [nTPM]":"40.7","Blood RNA - naive CD8 T-cell [nTPM]":"37.0","Blood RNA - neutrophil [nTPM]":"67.7","Blood RNA - NK-cell [nTPM]":"43.9","Blood RNA - non-classical monocyte [nTPM]":"48.7","Blood RNA - plasmacytoid DC [nTPM]":"34.9","Blood RNA - T-reg [nTPM]":"59.0","Blood RNA - total PBMC [nTPM]":"52.8","Brain RNA - amygdala [nTPM]":"30.3","Brain RNA - basal ganglia [nTPM]":"33.1","Brain RNA - cerebellum [nTPM]":"35.0","Brain RNA - cerebral cortex [nTPM]":"36.2","Brain RNA - hippocampal formation [nTPM]":"31.3","Brain RNA - hypothalamus [nTPM]":"35.6","Brain RNA - medulla oblongata [nTPM]":"36.6","Brain RNA - midbrain [nTPM]":"35.2","Brain RNA - pons [nTPM]":"35.9","Brain RNA - spinal cord [nTPM]":"37.9","Brain RNA - thalamus [nTPM]":"34.0","Brain RNA - white matter [nTPM]":"44.5","Single Cell Type RNA - Adipocytes [nTPM]":"71.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"83.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.3","Single Cell Type RNA - Astrocytes [nTPM]":"13.4","Single Cell Type RNA - B-cells [nTPM]":"69.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"246.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"44.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"33.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"89.4","Single Cell Type RNA - Bipolar cells [nTPM]":"31.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"40.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"38.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"20.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"19.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"281.8","Single Cell Type RNA - dendritic cells [nTPM]":"40.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"34.9","Single Cell Type RNA - Early spermatids [nTPM]":"27.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"54.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"90.2","Single Cell Type RNA - Endothelial cells [nTPM]":"66.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.9","Single Cell Type RNA - Erythroid cells [nTPM]":"18.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"43.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"48.3","Single Cell Type RNA - Fibroblasts [nTPM]":"77.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"146.1","Single Cell Type RNA - granulocytes [nTPM]":"106.5","Single Cell Type RNA - Granulosa cells [nTPM]":"21.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"55.6","Single Cell Type RNA - Hepatocytes [nTPM]":"20.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"93.0","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.2","Single Cell Type RNA - Ionocytes [nTPM]":"34.6","Single Cell Type RNA - Kupffer cells [nTPM]":"57.8","Single Cell Type RNA - Langerhans cells [nTPM]":"90.5","Single Cell Type RNA - Late spermatids [nTPM]":"13.6","Single Cell Type RNA - Leydig cells [nTPM]":"63.0","Single Cell Type RNA - Macrophages [nTPM]":"72.8","Single Cell Type RNA - Melanocytes [nTPM]":"69.4","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"57.1","Single Cell Type RNA - Muller glia cells [nTPM]":"26.0","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"25.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"32.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.5","Single Cell Type RNA - Paneth cells [nTPM]":"5.9","Single Cell Type RNA - Peritubular cells [nTPM]":"79.4","Single Cell Type RNA - Plasma cells [nTPM]":"50.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"44.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"29.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.4","Single Cell Type RNA - Sertoli cells [nTPM]":"105.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"42.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"89.1","Single Cell Type RNA - Spermatocytes [nTPM]":"84.3","Single Cell Type RNA - Spermatogonia [nTPM]":"44.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"50.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"320.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"198.9","Single Cell Type RNA - T-cells [nTPM]":"58.9","Single Cell Type RNA - Theca cells [nTPM]":"43.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.6","Single Cell Type RNA - Urothelial cells [nTPM]":"13.7"},{"Gene":"DGAT1","Gene synonym":["ARGP1","DGAT"],"Ensembl":"ENSG00000185000","Gene description":"Diacylglycerol O-acyltransferase 1","Uniprot":["O75907"],"Chromosome":"8","Position":"144314584-144326910","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"40.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Distal enterocytes":"213.5","Proximal enterocytes":"700.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"18.4","PC-3":"21.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB032853"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Nucleoli rim","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Nucleoli","Nucleoli rim"],"Antibody RRID":{"CAB032853":"AB_2090798"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-3"},"Tissue RNA - adipose tissue [nTPM]":"15.0","Tissue RNA - adrenal gland [nTPM]":"24.7","Tissue RNA - amygdala [nTPM]":"4.6","Tissue RNA - appendix [nTPM]":"1.8","Tissue RNA - basal ganglia [nTPM]":"4.6","Tissue RNA - bone marrow [nTPM]":"5.1","Tissue RNA - breast [nTPM]":"11.8","Tissue RNA - cerebellum [nTPM]":"5.5","Tissue RNA - cerebral cortex [nTPM]":"5.6","Tissue RNA - cervix [nTPM]":"6.1","Tissue RNA - choroid plexus [nTPM]":"4.1","Tissue RNA - colon [nTPM]":"16.7","Tissue RNA - duodenum [nTPM]":"37.0","Tissue RNA - endometrium 1 [nTPM]":"5.6","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"8.6","Tissue RNA - fallopian tube [nTPM]":"5.1","Tissue RNA - gallbladder [nTPM]":"2.0","Tissue RNA - heart muscle [nTPM]":"11.7","Tissue RNA - hippocampal formation [nTPM]":"4.7","Tissue RNA - hypothalamus [nTPM]":"4.1","Tissue RNA - kidney [nTPM]":"7.9","Tissue RNA - liver [nTPM]":"16.5","Tissue RNA - lung [nTPM]":"6.9","Tissue RNA - lymph node [nTPM]":"1.8","Tissue RNA - medulla oblongata [nTPM]":"4.5","Tissue RNA - midbrain [nTPM]":"4.6","Tissue RNA - ovary [nTPM]":"4.3","Tissue RNA - pancreas [nTPM]":"6.5","Tissue RNA - parathyroid gland [nTPM]":"3.9","Tissue RNA - pituitary gland [nTPM]":"6.5","Tissue RNA - placenta [nTPM]":"1.5","Tissue RNA - pons [nTPM]":"4.2","Tissue RNA - prostate [nTPM]":"6.6","Tissue RNA - rectum [nTPM]":"4.2","Tissue RNA - retina [nTPM]":"1.6","Tissue RNA - salivary gland [nTPM]":"7.4","Tissue RNA - seminal vesicle [nTPM]":"2.4","Tissue RNA - skeletal muscle [nTPM]":"11.7","Tissue RNA - skin 1 [nTPM]":"6.9","Tissue RNA - small intestine [nTPM]":"40.6","Tissue RNA - smooth muscle [nTPM]":"1.6","Tissue RNA - spinal cord [nTPM]":"4.1","Tissue RNA - spleen [nTPM]":"9.3","Tissue RNA - stomach 1 [nTPM]":"8.7","Tissue RNA - testis [nTPM]":"14.7","Tissue RNA - thalamus [nTPM]":"4.4","Tissue RNA - thymus [nTPM]":"2.3","Tissue RNA - thyroid gland [nTPM]":"7.4","Tissue RNA - tongue [nTPM]":"3.5","Tissue RNA - tonsil [nTPM]":"1.4","Tissue RNA - urinary bladder [nTPM]":"6.7","Tissue RNA - vagina [nTPM]":"6.4","Tissue RNA - white matter [nTPM]":"4.5","Cell RNA - A-431 [nTPM]":"5.2","Cell RNA - A549 [nTPM]":"4.9","Cell RNA - AF22 [nTPM]":"2.2","Cell RNA - AN3-CA [nTPM]":"4.1","Cell RNA - ASC diff [nTPM]":"3.5","Cell RNA - ASC TERT1 [nTPM]":"1.5","Cell RNA - BEWO [nTPM]":"2.9","Cell RNA - BJ [nTPM]":"3.4","Cell RNA - BJ hTERT+ [nTPM]":"3.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.0","Cell RNA - CACO-2 [nTPM]":"11.2","Cell RNA - CAPAN-2 [nTPM]":"3.1","Cell RNA - Daudi [nTPM]":"2.1","Cell RNA - EFO-21 [nTPM]":"12.4","Cell RNA - fHDF\/TERT166 [nTPM]":"1.9","Cell RNA - GAMG [nTPM]":"1.6","Cell RNA - HaCaT [nTPM]":"4.0","Cell RNA - HAP1 [nTPM]":"1.8","Cell RNA - HBEC3-KT [nTPM]":"4.3","Cell RNA - HBF TERT88 [nTPM]":"0.6","Cell RNA - HDLM-2 [nTPM]":"3.7","Cell RNA - HEK 293 [nTPM]":"5.1","Cell RNA - HEL [nTPM]":"3.3","Cell RNA - HeLa [nTPM]":"4.2","Cell RNA - Hep G2 [nTPM]":"18.4","Cell RNA - HHSteC [nTPM]":"2.5","Cell RNA - HL-60 [nTPM]":"1.0","Cell RNA - HMC-1 [nTPM]":"3.4","Cell RNA - HSkMC [nTPM]":"2.1","Cell RNA - hTCEpi [nTPM]":"3.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.0","Cell RNA - hTERT-HME1 [nTPM]":"2.1","Cell RNA - hTERT-RPE1 [nTPM]":"2.1","Cell RNA - HUVEC TERT2 [nTPM]":"2.3","Cell RNA - JURKAT [nTPM]":"7.3","Cell RNA - K-562 [nTPM]":"2.9","Cell RNA - Karpas-707 [nTPM]":"5.2","Cell RNA - LHCN-M2 [nTPM]":"1.9","Cell RNA - MCF7 [nTPM]":"3.7","Cell RNA - MOLT-4 [nTPM]":"6.8","Cell RNA - NB-4 [nTPM]":"4.1","Cell RNA - NTERA-2 [nTPM]":"1.1","Cell RNA - OE19 [nTPM]":"10.9","Cell RNA - PC-3 [nTPM]":"21.2","Cell RNA - REH [nTPM]":"7.7","Cell RNA - RH-30 [nTPM]":"0.9","Cell RNA - RPMI-8226 [nTPM]":"3.4","Cell RNA - RPTEC TERT1 [nTPM]":"2.8","Cell RNA - RT4 [nTPM]":"2.5","Cell RNA - SCLC-21H [nTPM]":"2.6","Cell RNA - SH-SY5Y [nTPM]":"4.2","Cell RNA - SiHa [nTPM]":"4.7","Cell RNA - SK-BR-3 [nTPM]":"5.2","Cell RNA - SK-MEL-30 [nTPM]":"2.3","Cell RNA - SuSa [nTPM]":"0.8","Cell RNA - T-47d [nTPM]":"2.9","Cell RNA - THP-1 [nTPM]":"3.3","Cell RNA - TIME [nTPM]":"2.0","Cell RNA - U-138 MG [nTPM]":"1.6","Cell RNA - U-2 OS [nTPM]":"5.6","Cell RNA - U-2197 [nTPM]":"3.6","Cell RNA - U-251 MG [nTPM]":"2.8","Cell RNA - U-266\/70 [nTPM]":"2.3","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"0.8","Cell RNA - U-87 MG [nTPM]":"1.8","Cell RNA - U-937 [nTPM]":"6.3","Cell RNA - WM-115 [nTPM]":"3.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"4.6","Brain RNA - basal ganglia [nTPM]":"4.6","Brain RNA - cerebellum [nTPM]":"5.5","Brain RNA - cerebral cortex [nTPM]":"5.6","Brain RNA - hippocampal formation [nTPM]":"4.7","Brain RNA - hypothalamus [nTPM]":"4.1","Brain RNA - medulla oblongata [nTPM]":"4.5","Brain RNA - midbrain [nTPM]":"4.6","Brain RNA - pons [nTPM]":"4.2","Brain RNA - spinal cord [nTPM]":"4.1","Brain RNA - thalamus [nTPM]":"4.4","Brain RNA - white matter [nTPM]":"4.5","Single Cell Type RNA - Adipocytes [nTPM]":"34.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.0","Single Cell Type RNA - Astrocytes [nTPM]":"15.7","Single Cell Type RNA - B-cells [nTPM]":"8.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"24.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"20.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"8.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.3","Single Cell Type RNA - dendritic cells [nTPM]":"17.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"213.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.4","Single Cell Type RNA - Early spermatids [nTPM]":"19.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.7","Single Cell Type RNA - Endothelial cells [nTPM]":"26.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"23.4","Single Cell Type RNA - Erythroid cells [nTPM]":"17.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.3","Single Cell Type RNA - Fibroblasts [nTPM]":"9.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"48.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.3","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"23.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.5","Single Cell Type RNA - Hepatocytes [nTPM]":"57.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.8","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"93.6","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"25.5","Single Cell Type RNA - Langerhans cells [nTPM]":"11.8","Single Cell Type RNA - Late spermatids [nTPM]":"25.8","Single Cell Type RNA - Leydig cells [nTPM]":"6.8","Single Cell Type RNA - Macrophages [nTPM]":"22.8","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"9.2","Single Cell Type RNA - Muller glia cells [nTPM]":"21.3","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.3","Single Cell Type RNA - Paneth cells [nTPM]":"113.4","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"18.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"700.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.3","Single Cell Type RNA - Spermatocytes [nTPM]":"27.7","Single Cell Type RNA - Spermatogonia [nTPM]":"17.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.4","Single Cell Type RNA - T-cells [nTPM]":"12.3","Single Cell Type RNA - Theca cells [nTPM]":"41.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"108.0","Single Cell Type RNA - Urothelial cells [nTPM]":"20.7"},{"Gene":"DGKE","Gene synonym":["DAGK6","DGK"],"Ensembl":"ENSG00000153933","Gene description":"Diacylglycerol kinase epsilon","Uniprot":["P52429"],"Chromosome":"17","Position":"56834107-56869567","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant","Hemolytic uremic syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"34.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"181.1","Cone photoreceptor cells":"189.7","Inhibitory neurons":"90.0","Rod photoreceptor cells":"165.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"84.8","MOLT-4":"30.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017167"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA017167":"AB_1847638"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.92e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-3"},"Tissue RNA - adipose tissue [nTPM]":"4.1","Tissue RNA - adrenal gland [nTPM]":"2.2","Tissue RNA - amygdala [nTPM]":"5.4","Tissue RNA - appendix [nTPM]":"4.5","Tissue RNA - basal ganglia [nTPM]":"6.9","Tissue RNA - bone marrow [nTPM]":"3.1","Tissue RNA - breast [nTPM]":"3.0","Tissue RNA - cerebellum [nTPM]":"9.4","Tissue RNA - cerebral cortex [nTPM]":"7.4","Tissue RNA - cervix [nTPM]":"4.9","Tissue RNA - choroid plexus [nTPM]":"7.7","Tissue RNA - colon [nTPM]":"4.9","Tissue RNA - duodenum [nTPM]":"2.6","Tissue RNA - endometrium 1 [nTPM]":"6.5","Tissue RNA - epididymis [nTPM]":"4.2","Tissue RNA - esophagus [nTPM]":"2.6","Tissue RNA - fallopian tube [nTPM]":"4.8","Tissue RNA - gallbladder [nTPM]":"4.6","Tissue RNA - heart muscle [nTPM]":"2.9","Tissue RNA - hippocampal formation [nTPM]":"5.8","Tissue RNA - hypothalamus [nTPM]":"8.1","Tissue RNA - kidney [nTPM]":"2.6","Tissue RNA - liver [nTPM]":"2.8","Tissue RNA - lung [nTPM]":"5.2","Tissue RNA - lymph node [nTPM]":"5.0","Tissue RNA - medulla oblongata [nTPM]":"3.3","Tissue RNA - midbrain [nTPM]":"4.7","Tissue RNA - ovary [nTPM]":"3.5","Tissue RNA - pancreas [nTPM]":"3.9","Tissue RNA - parathyroid gland [nTPM]":"4.1","Tissue RNA - pituitary gland [nTPM]":"6.2","Tissue RNA - placenta [nTPM]":"2.7","Tissue RNA - pons [nTPM]":"3.4","Tissue RNA - prostate [nTPM]":"4.1","Tissue RNA - rectum [nTPM]":"3.3","Tissue RNA - retina [nTPM]":"34.5","Tissue RNA - salivary gland [nTPM]":"2.5","Tissue RNA - seminal vesicle [nTPM]":"3.3","Tissue RNA - skeletal muscle [nTPM]":"1.2","Tissue RNA - skin 1 [nTPM]":"1.9","Tissue RNA - small intestine [nTPM]":"4.4","Tissue RNA - smooth muscle [nTPM]":"4.3","Tissue RNA - spinal cord [nTPM]":"2.7","Tissue RNA - spleen [nTPM]":"6.9","Tissue RNA - stomach 1 [nTPM]":"3.7","Tissue RNA - testis [nTPM]":"6.5","Tissue RNA - thalamus [nTPM]":"6.9","Tissue RNA - thymus [nTPM]":"9.8","Tissue RNA - thyroid gland [nTPM]":"4.0","Tissue RNA - tongue [nTPM]":"2.2","Tissue RNA - tonsil [nTPM]":"4.3","Tissue RNA - urinary bladder [nTPM]":"3.8","Tissue RNA - vagina [nTPM]":"4.2","Tissue RNA - white matter [nTPM]":"5.8","Cell RNA - A-431 [nTPM]":"3.5","Cell RNA - A549 [nTPM]":"3.3","Cell RNA - AF22 [nTPM]":"3.0","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.6","Cell RNA - ASC TERT1 [nTPM]":"1.0","Cell RNA - BEWO [nTPM]":"1.4","Cell RNA - BJ [nTPM]":"5.8","Cell RNA - BJ hTERT+ [nTPM]":"4.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.5","Cell RNA - CACO-2 [nTPM]":"7.7","Cell RNA - CAPAN-2 [nTPM]":"4.2","Cell RNA - Daudi [nTPM]":"5.1","Cell RNA - EFO-21 [nTPM]":"7.0","Cell RNA - fHDF\/TERT166 [nTPM]":"3.1","Cell RNA - GAMG [nTPM]":"1.9","Cell RNA - HaCaT [nTPM]":"4.2","Cell RNA - HAP1 [nTPM]":"7.2","Cell RNA - HBEC3-KT [nTPM]":"3.2","Cell RNA - HBF TERT88 [nTPM]":"7.8","Cell RNA - HDLM-2 [nTPM]":"16.5","Cell RNA - HEK 293 [nTPM]":"9.5","Cell RNA - HEL [nTPM]":"6.6","Cell RNA - HeLa [nTPM]":"8.9","Cell RNA - Hep G2 [nTPM]":"5.1","Cell RNA - HHSteC [nTPM]":"3.3","Cell RNA - HL-60 [nTPM]":"12.7","Cell RNA - HMC-1 [nTPM]":"8.9","Cell RNA - HSkMC [nTPM]":"1.9","Cell RNA - hTCEpi [nTPM]":"4.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.1","Cell RNA - hTERT-HME1 [nTPM]":"8.0","Cell RNA - hTERT-RPE1 [nTPM]":"3.6","Cell RNA - HUVEC TERT2 [nTPM]":"5.4","Cell RNA - JURKAT [nTPM]":"14.7","Cell RNA - K-562 [nTPM]":"5.5","Cell RNA - Karpas-707 [nTPM]":"84.8","Cell RNA - LHCN-M2 [nTPM]":"4.8","Cell RNA - MCF7 [nTPM]":"5.1","Cell RNA - MOLT-4 [nTPM]":"30.3","Cell RNA - NB-4 [nTPM]":"7.1","Cell RNA - NTERA-2 [nTPM]":"2.3","Cell RNA - OE19 [nTPM]":"4.6","Cell RNA - PC-3 [nTPM]":"10.0","Cell RNA - REH [nTPM]":"9.4","Cell RNA - RH-30 [nTPM]":"12.4","Cell RNA - RPMI-8226 [nTPM]":"12.2","Cell RNA - RPTEC TERT1 [nTPM]":"3.9","Cell RNA - RT4 [nTPM]":"7.6","Cell RNA - SCLC-21H [nTPM]":"4.7","Cell RNA - SH-SY5Y [nTPM]":"3.2","Cell RNA - SiHa [nTPM]":"4.7","Cell RNA - SK-BR-3 [nTPM]":"2.5","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"1.9","Cell RNA - T-47d [nTPM]":"5.3","Cell RNA - THP-1 [nTPM]":"6.0","Cell RNA - TIME [nTPM]":"5.0","Cell RNA - U-138 MG [nTPM]":"1.1","Cell RNA - U-2 OS [nTPM]":"5.4","Cell RNA - U-2197 [nTPM]":"1.7","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"11.3","Cell RNA - U-266\/84 [nTPM]":"25.3","Cell RNA - U-698 [nTPM]":"3.4","Cell RNA - U-87 MG [nTPM]":"3.3","Cell RNA - U-937 [nTPM]":"7.3","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"1.7","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"5.4","Brain RNA - basal ganglia [nTPM]":"6.9","Brain RNA - cerebellum [nTPM]":"9.4","Brain RNA - cerebral cortex [nTPM]":"7.4","Brain RNA - hippocampal formation [nTPM]":"5.8","Brain RNA - hypothalamus [nTPM]":"8.1","Brain RNA - medulla oblongata [nTPM]":"3.3","Brain RNA - midbrain [nTPM]":"4.7","Brain RNA - pons [nTPM]":"3.4","Brain RNA - spinal cord [nTPM]":"2.7","Brain RNA - thalamus [nTPM]":"6.9","Brain RNA - white matter [nTPM]":"5.8","Single Cell Type RNA - Adipocytes [nTPM]":"51.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.0","Single Cell Type RNA - Astrocytes [nTPM]":"10.4","Single Cell Type RNA - B-cells [nTPM]":"11.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.6","Single Cell Type RNA - Bipolar cells [nTPM]":"181.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"4.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"189.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.6","Single Cell Type RNA - dendritic cells [nTPM]":"16.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"7.4","Single Cell Type RNA - Early spermatids [nTPM]":"18.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.9","Single Cell Type RNA - Endothelial cells [nTPM]":"30.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.3","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"66.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.0","Single Cell Type RNA - Fibroblasts [nTPM]":"6.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"13.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"29.3","Single Cell Type RNA - Hepatocytes [nTPM]":"4.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.2","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"90.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.7","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.0","Single Cell Type RNA - Langerhans cells [nTPM]":"9.3","Single Cell Type RNA - Late spermatids [nTPM]":"9.2","Single Cell Type RNA - Leydig cells [nTPM]":"4.4","Single Cell Type RNA - Macrophages [nTPM]":"7.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"32.8","Single Cell Type RNA - monocytes [nTPM]":"6.3","Single Cell Type RNA - Muller glia cells [nTPM]":"18.6","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"32.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.0","Single Cell Type RNA - Paneth cells [nTPM]":"6.4","Single Cell Type RNA - Peritubular cells [nTPM]":"5.3","Single Cell Type RNA - Plasma cells [nTPM]":"15.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"21.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"165.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.7","Single Cell Type RNA - Spermatocytes [nTPM]":"28.5","Single Cell Type RNA - Spermatogonia [nTPM]":"20.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - T-cells [nTPM]":"18.9","Single Cell Type RNA - Theca cells [nTPM]":"5.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.8","Single Cell Type RNA - Urothelial cells [nTPM]":"13.4"},{"Gene":"DGUOK","Gene synonym":["dGK"],"Ensembl":"ENSG00000114956","Gene description":"Deoxyguanosine kinase","Uniprot":["Q16854"],"Chromosome":"2","Position":"73926826-73958961","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant","Neuropathy","Primary mitochondrial disease","Progressive external ophthalmoplegia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034766","HPA057246"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA034766":"AB_10669850","HPA057246":"AB_2683381"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.69e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.47e-4"},"Tissue RNA - adipose tissue [nTPM]":"20.8","Tissue RNA - adrenal gland [nTPM]":"30.0","Tissue RNA - amygdala [nTPM]":"37.1","Tissue RNA - appendix [nTPM]":"20.3","Tissue RNA - basal ganglia [nTPM]":"39.2","Tissue RNA - bone marrow [nTPM]":"27.1","Tissue RNA - breast [nTPM]":"28.1","Tissue RNA - cerebellum [nTPM]":"36.5","Tissue RNA - cerebral cortex [nTPM]":"48.4","Tissue RNA - cervix [nTPM]":"23.0","Tissue RNA - choroid plexus [nTPM]":"36.8","Tissue RNA - colon [nTPM]":"25.0","Tissue RNA - duodenum [nTPM]":"17.7","Tissue RNA - endometrium 1 [nTPM]":"23.1","Tissue RNA - epididymis [nTPM]":"34.4","Tissue RNA - esophagus [nTPM]":"21.8","Tissue RNA - fallopian tube [nTPM]":"31.3","Tissue RNA - gallbladder [nTPM]":"19.4","Tissue RNA - heart muscle [nTPM]":"23.0","Tissue RNA - hippocampal formation [nTPM]":"38.5","Tissue RNA - hypothalamus [nTPM]":"42.8","Tissue RNA - kidney [nTPM]":"24.6","Tissue RNA - liver [nTPM]":"30.5","Tissue RNA - lung [nTPM]":"17.7","Tissue RNA - lymph node [nTPM]":"36.8","Tissue RNA - medulla oblongata [nTPM]":"37.9","Tissue RNA - midbrain [nTPM]":"37.7","Tissue RNA - ovary [nTPM]":"30.0","Tissue RNA - pancreas [nTPM]":"16.3","Tissue RNA - parathyroid gland [nTPM]":"11.0","Tissue RNA - pituitary gland [nTPM]":"41.3","Tissue RNA - placenta [nTPM]":"21.5","Tissue RNA - pons [nTPM]":"39.1","Tissue RNA - prostate [nTPM]":"24.5","Tissue RNA - rectum [nTPM]":"29.1","Tissue RNA - retina [nTPM]":"34.5","Tissue RNA - salivary gland [nTPM]":"19.8","Tissue RNA - seminal vesicle [nTPM]":"22.5","Tissue RNA - skeletal muscle [nTPM]":"17.1","Tissue RNA - skin 1 [nTPM]":"26.5","Tissue RNA - small intestine [nTPM]":"20.2","Tissue RNA - smooth muscle [nTPM]":"21.9","Tissue RNA - spinal cord [nTPM]":"37.9","Tissue RNA - spleen [nTPM]":"25.9","Tissue RNA - stomach 1 [nTPM]":"21.0","Tissue RNA - testis [nTPM]":"32.8","Tissue RNA - thalamus [nTPM]":"38.8","Tissue RNA - thymus [nTPM]":"36.3","Tissue RNA - thyroid gland [nTPM]":"22.6","Tissue RNA - tongue [nTPM]":"17.7","Tissue RNA - tonsil [nTPM]":"40.9","Tissue RNA - urinary bladder [nTPM]":"22.2","Tissue RNA - vagina [nTPM]":"20.9","Tissue RNA - white matter [nTPM]":"38.8","Cell RNA - A-431 [nTPM]":"45.1","Cell RNA - A549 [nTPM]":"72.5","Cell RNA - AF22 [nTPM]":"74.4","Cell RNA - AN3-CA [nTPM]":"67.9","Cell RNA - ASC diff [nTPM]":"47.8","Cell RNA - ASC TERT1 [nTPM]":"53.8","Cell RNA - BEWO [nTPM]":"37.1","Cell RNA - BJ [nTPM]":"29.3","Cell RNA - BJ hTERT+ [nTPM]":"56.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"66.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"61.1","Cell RNA - CACO-2 [nTPM]":"91.2","Cell RNA - CAPAN-2 [nTPM]":"51.5","Cell RNA - Daudi [nTPM]":"83.0","Cell RNA - EFO-21 [nTPM]":"27.4","Cell RNA - fHDF\/TERT166 [nTPM]":"42.1","Cell RNA - GAMG [nTPM]":"74.1","Cell RNA - HaCaT [nTPM]":"34.7","Cell RNA - HAP1 [nTPM]":"85.4","Cell RNA - HBEC3-KT [nTPM]":"57.1","Cell RNA - HBF TERT88 [nTPM]":"79.3","Cell RNA - HDLM-2 [nTPM]":"47.1","Cell RNA - HEK 293 [nTPM]":"53.6","Cell RNA - HEL [nTPM]":"65.8","Cell RNA - HeLa [nTPM]":"25.4","Cell RNA - Hep G2 [nTPM]":"107.5","Cell RNA - HHSteC [nTPM]":"70.5","Cell RNA - HL-60 [nTPM]":"62.1","Cell RNA - HMC-1 [nTPM]":"66.0","Cell RNA - HSkMC [nTPM]":"49.7","Cell RNA - hTCEpi [nTPM]":"51.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"50.4","Cell RNA - hTERT-HME1 [nTPM]":"58.9","Cell RNA - hTERT-RPE1 [nTPM]":"48.6","Cell RNA - HUVEC TERT2 [nTPM]":"48.3","Cell RNA - JURKAT [nTPM]":"91.4","Cell RNA - K-562 [nTPM]":"67.2","Cell RNA - Karpas-707 [nTPM]":"37.0","Cell RNA - LHCN-M2 [nTPM]":"78.8","Cell RNA - MCF7 [nTPM]":"54.4","Cell RNA - MOLT-4 [nTPM]":"59.6","Cell RNA - NB-4 [nTPM]":"101.2","Cell RNA - NTERA-2 [nTPM]":"76.7","Cell RNA - OE19 [nTPM]":"60.5","Cell RNA - PC-3 [nTPM]":"53.9","Cell RNA - REH [nTPM]":"73.8","Cell RNA - RH-30 [nTPM]":"73.1","Cell RNA - RPMI-8226 [nTPM]":"59.7","Cell RNA - RPTEC TERT1 [nTPM]":"55.8","Cell RNA - RT4 [nTPM]":"49.6","Cell RNA - SCLC-21H [nTPM]":"85.0","Cell RNA - SH-SY5Y [nTPM]":"82.6","Cell RNA - SiHa [nTPM]":"27.9","Cell RNA - SK-BR-3 [nTPM]":"28.2","Cell RNA - SK-MEL-30 [nTPM]":"77.1","Cell RNA - SuSa [nTPM]":"35.5","Cell RNA - T-47d [nTPM]":"34.0","Cell RNA - THP-1 [nTPM]":"34.8","Cell RNA - TIME [nTPM]":"45.3","Cell RNA - U-138 MG [nTPM]":"43.3","Cell RNA - U-2 OS [nTPM]":"68.8","Cell RNA - U-2197 [nTPM]":"37.8","Cell RNA - U-251 MG [nTPM]":"52.6","Cell RNA - U-266\/70 [nTPM]":"32.3","Cell RNA - U-266\/84 [nTPM]":"31.4","Cell RNA - U-698 [nTPM]":"86.1","Cell RNA - U-87 MG [nTPM]":"62.2","Cell RNA - U-937 [nTPM]":"65.9","Cell RNA - WM-115 [nTPM]":"95.1","Blood RNA - basophil [nTPM]":"129.8","Blood RNA - classical monocyte [nTPM]":"70.9","Blood RNA - eosinophil [nTPM]":"138.7","Blood RNA - gdT-cell [nTPM]":"62.3","Blood RNA - intermediate monocyte [nTPM]":"87.3","Blood RNA - MAIT T-cell [nTPM]":"72.4","Blood RNA - memory B-cell [nTPM]":"108.5","Blood RNA - memory CD4 T-cell [nTPM]":"77.0","Blood RNA - memory CD8 T-cell [nTPM]":"69.6","Blood RNA - myeloid DC [nTPM]":"81.6","Blood RNA - naive B-cell [nTPM]":"114.5","Blood RNA - naive CD4 T-cell [nTPM]":"98.6","Blood RNA - naive CD8 T-cell [nTPM]":"79.6","Blood RNA - neutrophil [nTPM]":"56.4","Blood RNA - NK-cell [nTPM]":"79.4","Blood RNA - non-classical monocyte [nTPM]":"84.7","Blood RNA - plasmacytoid DC [nTPM]":"91.3","Blood RNA - T-reg [nTPM]":"79.9","Blood RNA - total PBMC [nTPM]":"91.3","Brain RNA - amygdala [nTPM]":"37.1","Brain RNA - basal ganglia [nTPM]":"39.2","Brain RNA - cerebellum [nTPM]":"36.5","Brain RNA - cerebral cortex [nTPM]":"48.4","Brain RNA - hippocampal formation [nTPM]":"38.5","Brain RNA - hypothalamus [nTPM]":"42.8","Brain RNA - medulla oblongata [nTPM]":"37.9","Brain RNA - midbrain [nTPM]":"37.7","Brain RNA - pons [nTPM]":"39.1","Brain RNA - spinal cord [nTPM]":"37.9","Brain RNA - thalamus [nTPM]":"38.8","Brain RNA - white matter [nTPM]":"38.8","Single Cell Type RNA - Adipocytes [nTPM]":"72.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"42.8","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"103.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"74.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"138.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"249.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"88.2","Single Cell Type RNA - Bipolar cells [nTPM]":"52.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"85.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"128.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"78.6","Single Cell Type RNA - Club cells [nTPM]":"108.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"60.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"159.4","Single Cell Type RNA - dendritic cells [nTPM]":"89.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"58.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"84.1","Single Cell Type RNA - Ductal cells [nTPM]":"102.6","Single Cell Type RNA - Early spermatids [nTPM]":"12.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"82.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"69.1","Single Cell Type RNA - Endothelial cells [nTPM]":"74.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"113.1","Single Cell Type RNA - Erythroid cells [nTPM]":"67.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"149.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"165.4","Single Cell Type RNA - Fibroblasts [nTPM]":"88.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"40.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"82.6","Single Cell Type RNA - granulocytes [nTPM]":"57.6","Single Cell Type RNA - Granulosa cells [nTPM]":"87.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"76.1","Single Cell Type RNA - Hepatocytes [nTPM]":"69.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"90.9","Single Cell Type RNA - Horizontal cells [nTPM]":"52.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"100.1","Single Cell Type RNA - Ionocytes [nTPM]":"158.7","Single Cell Type RNA - Kupffer cells [nTPM]":"88.3","Single Cell Type RNA - Langerhans cells [nTPM]":"112.3","Single Cell Type RNA - Late spermatids [nTPM]":"15.1","Single Cell Type RNA - Leydig cells [nTPM]":"93.5","Single Cell Type RNA - Macrophages [nTPM]":"80.2","Single Cell Type RNA - Melanocytes [nTPM]":"110.3","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"151.9","Single Cell Type RNA - Muller glia cells [nTPM]":"89.5","Single Cell Type RNA - NK-cells [nTPM]":"118.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"27.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"173.0","Single Cell Type RNA - Paneth cells [nTPM]":"88.1","Single Cell Type RNA - Peritubular cells [nTPM]":"86.9","Single Cell Type RNA - Plasma cells [nTPM]":"70.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"146.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"88.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"119.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"87.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"40.4","Single Cell Type RNA - Sertoli cells [nTPM]":"92.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"55.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"89.3","Single Cell Type RNA - Spermatocytes [nTPM]":"105.3","Single Cell Type RNA - Spermatogonia [nTPM]":"129.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"88.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"83.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"124.5","Single Cell Type RNA - T-cells [nTPM]":"101.4","Single Cell Type RNA - Theca cells [nTPM]":"124.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"104.9","Single Cell Type RNA - Urothelial cells [nTPM]":"142.9"},{"Gene":"DHCR24","Gene synonym":["DCE","KIAA0018","seladin-1"],"Ensembl":"ENSG00000116133","Gene description":"24-dehydrocholesterol reductase","Uniprot":["Q15392"],"Chromosome":"1","Position":"54849627-54887195","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"1129.5","liver":"623.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"298.1","Alveolar cells type 2":"682.3","Hepatocytes":"1091.4","Theca cells":"442.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"1031.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017981","CAB037247","HPA063005"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB037247":"AB_796187","HPA017981":"AB_2732422","HPA063005":"AB_2684919"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.05e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Tissue RNA - adipose tissue [nTPM]":"58.3","Tissue RNA - adrenal gland [nTPM]":"1129.5","Tissue RNA - amygdala [nTPM]":"35.7","Tissue RNA - appendix [nTPM]":"19.8","Tissue RNA - basal ganglia [nTPM]":"58.5","Tissue RNA - bone marrow [nTPM]":"1.6","Tissue RNA - breast [nTPM]":"104.8","Tissue RNA - cerebellum [nTPM]":"125.3","Tissue RNA - cerebral cortex [nTPM]":"73.0","Tissue RNA - cervix [nTPM]":"54.9","Tissue RNA - choroid plexus [nTPM]":"30.4","Tissue RNA - colon [nTPM]":"55.6","Tissue RNA - duodenum [nTPM]":"62.2","Tissue RNA - endometrium 1 [nTPM]":"13.1","Tissue RNA - epididymis [nTPM]":"1.6","Tissue RNA - esophagus [nTPM]":"296.1","Tissue RNA - fallopian tube [nTPM]":"60.4","Tissue RNA - gallbladder [nTPM]":"42.2","Tissue RNA - heart muscle [nTPM]":"18.0","Tissue RNA - hippocampal formation [nTPM]":"55.9","Tissue RNA - hypothalamus [nTPM]":"63.9","Tissue RNA - kidney [nTPM]":"48.6","Tissue RNA - liver [nTPM]":"623.5","Tissue RNA - lung [nTPM]":"215.9","Tissue RNA - lymph node [nTPM]":"9.4","Tissue RNA - medulla oblongata [nTPM]":"216.2","Tissue RNA - midbrain [nTPM]":"91.3","Tissue RNA - ovary [nTPM]":"28.5","Tissue RNA - pancreas [nTPM]":"30.5","Tissue RNA - parathyroid gland [nTPM]":"157.9","Tissue RNA - pituitary gland [nTPM]":"17.0","Tissue RNA - placenta [nTPM]":"21.6","Tissue RNA - pons [nTPM]":"158.9","Tissue RNA - prostate [nTPM]":"128.6","Tissue RNA - rectum [nTPM]":"40.5","Tissue RNA - retina [nTPM]":"15.8","Tissue RNA - salivary gland [nTPM]":"136.2","Tissue RNA - seminal vesicle [nTPM]":"8.3","Tissue RNA - skeletal muscle [nTPM]":"197.7","Tissue RNA - skin 1 [nTPM]":"247.6","Tissue RNA - small intestine [nTPM]":"29.6","Tissue RNA - smooth muscle [nTPM]":"12.6","Tissue RNA - spinal cord [nTPM]":"129.3","Tissue RNA - spleen [nTPM]":"134.1","Tissue RNA - stomach 1 [nTPM]":"98.9","Tissue RNA - testis [nTPM]":"74.2","Tissue RNA - thalamus [nTPM]":"87.9","Tissue RNA - thymus [nTPM]":"10.1","Tissue RNA - thyroid gland [nTPM]":"15.4","Tissue RNA - tongue [nTPM]":"11.1","Tissue RNA - tonsil [nTPM]":"33.9","Tissue RNA - urinary bladder [nTPM]":"13.5","Tissue RNA - vagina [nTPM]":"103.9","Tissue RNA - white matter [nTPM]":"280.7","Cell RNA - A-431 [nTPM]":"342.1","Cell RNA - A549 [nTPM]":"58.5","Cell RNA - AF22 [nTPM]":"210.6","Cell RNA - AN3-CA [nTPM]":"257.1","Cell RNA - ASC diff [nTPM]":"1031.9","Cell RNA - ASC TERT1 [nTPM]":"219.0","Cell RNA - BEWO [nTPM]":"50.5","Cell RNA - BJ [nTPM]":"94.8","Cell RNA - BJ hTERT+ [nTPM]":"160.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"130.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"268.6","Cell RNA - CACO-2 [nTPM]":"341.6","Cell RNA - CAPAN-2 [nTPM]":"210.2","Cell RNA - Daudi [nTPM]":"55.3","Cell RNA - EFO-21 [nTPM]":"191.5","Cell RNA - fHDF\/TERT166 [nTPM]":"82.4","Cell RNA - GAMG [nTPM]":"427.4","Cell RNA - HaCaT [nTPM]":"319.2","Cell RNA - HAP1 [nTPM]":"250.5","Cell RNA - HBEC3-KT [nTPM]":"501.3","Cell RNA - HBF TERT88 [nTPM]":"118.3","Cell RNA - HDLM-2 [nTPM]":"8.3","Cell RNA - HEK 293 [nTPM]":"159.6","Cell RNA - HEL [nTPM]":"303.3","Cell RNA - HeLa [nTPM]":"131.8","Cell RNA - Hep G2 [nTPM]":"421.7","Cell RNA - HHSteC [nTPM]":"168.9","Cell RNA - HL-60 [nTPM]":"126.7","Cell RNA - HMC-1 [nTPM]":"68.2","Cell RNA - HSkMC [nTPM]":"161.0","Cell RNA - hTCEpi [nTPM]":"429.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"397.6","Cell RNA - hTERT-HME1 [nTPM]":"74.7","Cell RNA - hTERT-RPE1 [nTPM]":"66.7","Cell RNA - HUVEC TERT2 [nTPM]":"67.2","Cell RNA - JURKAT [nTPM]":"124.5","Cell RNA - K-562 [nTPM]":"224.7","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"50.2","Cell RNA - MCF7 [nTPM]":"143.5","Cell RNA - MOLT-4 [nTPM]":"25.8","Cell RNA - NB-4 [nTPM]":"111.4","Cell RNA - NTERA-2 [nTPM]":"592.0","Cell RNA - OE19 [nTPM]":"90.7","Cell RNA - PC-3 [nTPM]":"164.2","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"54.2","Cell RNA - RPMI-8226 [nTPM]":"166.3","Cell RNA - RPTEC TERT1 [nTPM]":"735.3","Cell RNA - RT4 [nTPM]":"257.1","Cell RNA - SCLC-21H [nTPM]":"144.5","Cell RNA - SH-SY5Y [nTPM]":"53.2","Cell RNA - SiHa [nTPM]":"185.0","Cell RNA - SK-BR-3 [nTPM]":"337.5","Cell RNA - SK-MEL-30 [nTPM]":"123.1","Cell RNA - SuSa [nTPM]":"221.6","Cell RNA - T-47d [nTPM]":"441.5","Cell RNA - THP-1 [nTPM]":"143.3","Cell RNA - TIME [nTPM]":"62.2","Cell RNA - U-138 MG [nTPM]":"45.3","Cell RNA - U-2 OS [nTPM]":"130.0","Cell RNA - U-2197 [nTPM]":"66.1","Cell RNA - U-251 MG [nTPM]":"183.9","Cell RNA - U-266\/70 [nTPM]":"22.7","Cell RNA - U-266\/84 [nTPM]":"55.0","Cell RNA - U-698 [nTPM]":"91.2","Cell RNA - U-87 MG [nTPM]":"32.8","Cell RNA - U-937 [nTPM]":"215.3","Cell RNA - WM-115 [nTPM]":"60.4","Blood RNA - basophil [nTPM]":"5.1","Blood RNA - classical monocyte [nTPM]":"1.5","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"6.0","Blood RNA - intermediate monocyte [nTPM]":"1.8","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"3.7","Blood RNA - memory CD4 T-cell [nTPM]":"2.5","Blood RNA - memory CD8 T-cell [nTPM]":"2.6","Blood RNA - myeloid DC [nTPM]":"5.2","Blood RNA - naive B-cell [nTPM]":"1.3","Blood RNA - naive CD4 T-cell [nTPM]":"2.2","Blood RNA - naive CD8 T-cell [nTPM]":"2.9","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"2.7","Blood RNA - non-classical monocyte [nTPM]":"0.7","Blood RNA - plasmacytoid DC [nTPM]":"3.0","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"4.4","Brain RNA - amygdala [nTPM]":"35.7","Brain RNA - basal ganglia [nTPM]":"58.5","Brain RNA - cerebellum [nTPM]":"125.3","Brain RNA - cerebral cortex [nTPM]":"73.0","Brain RNA - hippocampal formation [nTPM]":"55.9","Brain RNA - hypothalamus [nTPM]":"63.9","Brain RNA - medulla oblongata [nTPM]":"216.2","Brain RNA - midbrain [nTPM]":"91.3","Brain RNA - pons [nTPM]":"158.9","Brain RNA - spinal cord [nTPM]":"129.3","Brain RNA - thalamus [nTPM]":"87.9","Brain RNA - white matter [nTPM]":"280.7","Single Cell Type RNA - Adipocytes [nTPM]":"6.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"298.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"682.3","Single Cell Type RNA - Astrocytes [nTPM]":"12.4","Single Cell Type RNA - B-cells [nTPM]":"13.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"31.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"150.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"79.1","Single Cell Type RNA - Bipolar cells [nTPM]":"9.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"87.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"33.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"145.8","Single Cell Type RNA - Club cells [nTPM]":"205.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"68.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"35.2","Single Cell Type RNA - dendritic cells [nTPM]":"6.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"133.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"55.3","Single Cell Type RNA - Early spermatids [nTPM]":"22.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.8","Single Cell Type RNA - Endothelial cells [nTPM]":"13.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"24.0","Single Cell Type RNA - Erythroid cells [nTPM]":"71.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"76.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"34.4","Single Cell Type RNA - Fibroblasts [nTPM]":"17.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"38.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"44.7","Single Cell Type RNA - granulocytes [nTPM]":"32.2","Single Cell Type RNA - Granulosa cells [nTPM]":"26.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"111.0","Single Cell Type RNA - Hepatocytes [nTPM]":"1091.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.0","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"39.2","Single Cell Type RNA - Ionocytes [nTPM]":"69.2","Single Cell Type RNA - Kupffer cells [nTPM]":"68.9","Single Cell Type RNA - Langerhans cells [nTPM]":"8.2","Single Cell Type RNA - Late spermatids [nTPM]":"77.2","Single Cell Type RNA - Leydig cells [nTPM]":"14.0","Single Cell Type RNA - Macrophages [nTPM]":"9.4","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"6.8","Single Cell Type RNA - Muller glia cells [nTPM]":"3.6","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"62.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"48.6","Single Cell Type RNA - Paneth cells [nTPM]":"27.7","Single Cell Type RNA - Peritubular cells [nTPM]":"7.9","Single Cell Type RNA - Plasma cells [nTPM]":"1.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"52.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"136.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.2","Single Cell Type RNA - Spermatocytes [nTPM]":"5.4","Single Cell Type RNA - Spermatogonia [nTPM]":"14.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"145.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"80.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"30.6","Single Cell Type RNA - T-cells [nTPM]":"10.6","Single Cell Type RNA - Theca cells [nTPM]":"442.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"35.2","Single Cell Type RNA - Urothelial cells [nTPM]":"45.2"},{"Gene":"DHCR7","Gene synonym":["SLOS"],"Ensembl":"ENSG00000172893","Gene description":"7-dehydrocholesterol reductase","Uniprot":["Q9UBM7"],"Chromosome":"11","Position":"71428193-71452868","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"161.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"77.9","Granulosa cells":"81.3","Hepatocytes":"156.1","Theca cells":"103.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044280"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA044280":"AB_10794893"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.93e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.67e-4"},"Tissue RNA - adipose tissue [nTPM]":"23.7","Tissue RNA - adrenal gland [nTPM]":"97.2","Tissue RNA - amygdala [nTPM]":"28.1","Tissue RNA - appendix [nTPM]":"13.0","Tissue RNA - basal ganglia [nTPM]":"35.4","Tissue RNA - bone marrow [nTPM]":"46.7","Tissue RNA - breast [nTPM]":"36.3","Tissue RNA - cerebellum [nTPM]":"42.4","Tissue RNA - cerebral cortex [nTPM]":"37.0","Tissue RNA - cervix [nTPM]":"16.2","Tissue RNA - choroid plexus [nTPM]":"15.6","Tissue RNA - colon [nTPM]":"21.1","Tissue RNA - duodenum [nTPM]":"48.1","Tissue RNA - endometrium 1 [nTPM]":"10.6","Tissue RNA - epididymis [nTPM]":"59.2","Tissue RNA - esophagus [nTPM]":"42.2","Tissue RNA - fallopian tube [nTPM]":"12.5","Tissue RNA - gallbladder [nTPM]":"8.9","Tissue RNA - heart muscle [nTPM]":"28.8","Tissue RNA - hippocampal formation [nTPM]":"28.8","Tissue RNA - hypothalamus [nTPM]":"35.8","Tissue RNA - kidney [nTPM]":"16.3","Tissue RNA - liver [nTPM]":"161.1","Tissue RNA - lung [nTPM]":"21.8","Tissue RNA - lymph node [nTPM]":"6.0","Tissue RNA - medulla oblongata [nTPM]":"55.3","Tissue RNA - midbrain [nTPM]":"38.8","Tissue RNA - ovary [nTPM]":"54.4","Tissue RNA - pancreas [nTPM]":"16.6","Tissue RNA - parathyroid gland [nTPM]":"24.4","Tissue RNA - pituitary gland [nTPM]":"18.4","Tissue RNA - placenta [nTPM]":"8.3","Tissue RNA - pons [nTPM]":"55.8","Tissue RNA - prostate [nTPM]":"21.6","Tissue RNA - rectum [nTPM]":"14.4","Tissue RNA - retina [nTPM]":"8.7","Tissue RNA - salivary gland [nTPM]":"27.8","Tissue RNA - seminal vesicle [nTPM]":"7.1","Tissue RNA - skeletal muscle [nTPM]":"13.6","Tissue RNA - skin 1 [nTPM]":"68.2","Tissue RNA - small intestine [nTPM]":"19.3","Tissue RNA - smooth muscle [nTPM]":"9.9","Tissue RNA - spinal cord [nTPM]":"34.4","Tissue RNA - spleen [nTPM]":"9.6","Tissue RNA - stomach 1 [nTPM]":"19.1","Tissue RNA - testis [nTPM]":"31.0","Tissue RNA - thalamus [nTPM]":"38.0","Tissue RNA - thymus [nTPM]":"4.7","Tissue RNA - thyroid gland [nTPM]":"11.9","Tissue RNA - tongue [nTPM]":"13.2","Tissue RNA - tonsil [nTPM]":"9.4","Tissue RNA - urinary bladder [nTPM]":"7.9","Tissue RNA - vagina [nTPM]":"22.7","Tissue RNA - white matter [nTPM]":"58.9","Cell RNA - A-431 [nTPM]":"126.4","Cell RNA - A549 [nTPM]":"112.3","Cell RNA - AF22 [nTPM]":"106.7","Cell RNA - AN3-CA [nTPM]":"118.9","Cell RNA - ASC diff [nTPM]":"49.0","Cell RNA - ASC TERT1 [nTPM]":"75.8","Cell RNA - BEWO [nTPM]":"33.7","Cell RNA - BJ [nTPM]":"50.9","Cell RNA - BJ hTERT+ [nTPM]":"134.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"43.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"114.5","Cell RNA - CACO-2 [nTPM]":"419.8","Cell RNA - CAPAN-2 [nTPM]":"401.5","Cell RNA - Daudi [nTPM]":"87.1","Cell RNA - EFO-21 [nTPM]":"79.0","Cell RNA - fHDF\/TERT166 [nTPM]":"48.6","Cell RNA - GAMG [nTPM]":"376.2","Cell RNA - HaCaT [nTPM]":"235.9","Cell RNA - HAP1 [nTPM]":"128.8","Cell RNA - HBEC3-KT [nTPM]":"276.7","Cell RNA - HBF TERT88 [nTPM]":"44.5","Cell RNA - HDLM-2 [nTPM]":"33.5","Cell RNA - HEK 293 [nTPM]":"98.7","Cell RNA - HEL [nTPM]":"33.4","Cell RNA - HeLa [nTPM]":"89.3","Cell RNA - Hep G2 [nTPM]":"183.1","Cell RNA - HHSteC [nTPM]":"127.8","Cell RNA - HL-60 [nTPM]":"63.7","Cell RNA - HMC-1 [nTPM]":"15.6","Cell RNA - HSkMC [nTPM]":"89.2","Cell RNA - hTCEpi [nTPM]":"122.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"159.3","Cell RNA - hTERT-HME1 [nTPM]":"108.4","Cell RNA - hTERT-RPE1 [nTPM]":"34.6","Cell RNA - HUVEC TERT2 [nTPM]":"63.8","Cell RNA - JURKAT [nTPM]":"112.7","Cell RNA - K-562 [nTPM]":"159.6","Cell RNA - Karpas-707 [nTPM]":"180.7","Cell RNA - LHCN-M2 [nTPM]":"43.2","Cell RNA - MCF7 [nTPM]":"341.1","Cell RNA - MOLT-4 [nTPM]":"52.4","Cell RNA - NB-4 [nTPM]":"72.6","Cell RNA - NTERA-2 [nTPM]":"154.1","Cell RNA - OE19 [nTPM]":"124.9","Cell RNA - PC-3 [nTPM]":"67.4","Cell RNA - REH [nTPM]":"46.9","Cell RNA - RH-30 [nTPM]":"150.6","Cell RNA - RPMI-8226 [nTPM]":"377.3","Cell RNA - RPTEC TERT1 [nTPM]":"162.3","Cell RNA - RT4 [nTPM]":"187.3","Cell RNA - SCLC-21H [nTPM]":"144.7","Cell RNA - SH-SY5Y [nTPM]":"53.9","Cell RNA - SiHa [nTPM]":"48.4","Cell RNA - SK-BR-3 [nTPM]":"157.6","Cell RNA - SK-MEL-30 [nTPM]":"113.9","Cell RNA - SuSa [nTPM]":"51.4","Cell RNA - T-47d [nTPM]":"153.2","Cell RNA - THP-1 [nTPM]":"34.5","Cell RNA - TIME [nTPM]":"60.4","Cell RNA - U-138 MG [nTPM]":"11.5","Cell RNA - U-2 OS [nTPM]":"62.4","Cell RNA - U-2197 [nTPM]":"3.7","Cell RNA - U-251 MG [nTPM]":"61.5","Cell RNA - U-266\/70 [nTPM]":"59.3","Cell RNA - U-266\/84 [nTPM]":"78.7","Cell RNA - U-698 [nTPM]":"95.8","Cell RNA - U-87 MG [nTPM]":"33.8","Cell RNA - U-937 [nTPM]":"110.9","Cell RNA - WM-115 [nTPM]":"48.9","Blood RNA - basophil [nTPM]":"5.6","Blood RNA - classical monocyte [nTPM]":"2.1","Blood RNA - eosinophil [nTPM]":"1.9","Blood RNA - gdT-cell [nTPM]":"10.5","Blood RNA - intermediate monocyte [nTPM]":"1.4","Blood RNA - MAIT T-cell [nTPM]":"12.6","Blood RNA - memory B-cell [nTPM]":"6.5","Blood RNA - memory CD4 T-cell [nTPM]":"8.9","Blood RNA - memory CD8 T-cell [nTPM]":"9.8","Blood RNA - myeloid DC [nTPM]":"2.8","Blood RNA - naive B-cell [nTPM]":"5.4","Blood RNA - naive CD4 T-cell [nTPM]":"11.0","Blood RNA - naive CD8 T-cell [nTPM]":"13.0","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"5.8","Blood RNA - non-classical monocyte [nTPM]":"1.5","Blood RNA - plasmacytoid DC [nTPM]":"7.1","Blood RNA - T-reg [nTPM]":"6.0","Blood RNA - total PBMC [nTPM]":"6.9","Brain RNA - amygdala [nTPM]":"28.1","Brain RNA - basal ganglia [nTPM]":"35.4","Brain RNA - cerebellum [nTPM]":"42.4","Brain RNA - cerebral cortex [nTPM]":"37.0","Brain RNA - hippocampal formation [nTPM]":"28.8","Brain RNA - hypothalamus [nTPM]":"35.8","Brain RNA - medulla oblongata [nTPM]":"55.3","Brain RNA - midbrain [nTPM]":"38.8","Brain RNA - pons [nTPM]":"55.8","Brain RNA - spinal cord [nTPM]":"34.4","Brain RNA - thalamus [nTPM]":"38.0","Brain RNA - white matter [nTPM]":"58.9","Single Cell Type RNA - Adipocytes [nTPM]":"7.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.1","Single Cell Type RNA - Astrocytes [nTPM]":"7.2","Single Cell Type RNA - B-cells [nTPM]":"7.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"77.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"8.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"39.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.5","Single Cell Type RNA - dendritic cells [nTPM]":"11.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"36.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.5","Single Cell Type RNA - Endothelial cells [nTPM]":"11.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.5","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"49.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"27.6","Single Cell Type RNA - Fibroblasts [nTPM]":"12.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"81.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"156.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.3","Single Cell Type RNA - Ionocytes [nTPM]":"54.9","Single Cell Type RNA - Kupffer cells [nTPM]":"3.8","Single Cell Type RNA - Langerhans cells [nTPM]":"3.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.7","Single Cell Type RNA - Leydig cells [nTPM]":"8.4","Single Cell Type RNA - Macrophages [nTPM]":"5.6","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"5.8","Single Cell Type RNA - Muller glia cells [nTPM]":"21.2","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"26.7","Single Cell Type RNA - Paneth cells [nTPM]":"11.5","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"10.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"7.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"54.2","Single Cell Type RNA - T-cells [nTPM]":"13.8","Single Cell Type RNA - Theca cells [nTPM]":"103.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.0","Single Cell Type RNA - Urothelial cells [nTPM]":"9.5"},{"Gene":"DHDDS","Gene synonym":["DS","FLJ13102","hCIT","HDS","RP59"],"Ensembl":"ENSG00000117682","Gene description":"Dehydrodolichyl diphosphate synthase subunit","Uniprot":["Q86SQ9"],"Chromosome":"1","Position":"26432282-26471306","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Epilepsy","Mental retardation","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"256.5","Early spermatids":"99.1","Rod photoreceptor cells":"106.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026721","HPA026727"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA026721":"AB_1847643","HPA026727":"AB_1847644"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.08e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Tissue RNA - adipose tissue [nTPM]":"57.3","Tissue RNA - adrenal gland [nTPM]":"19.6","Tissue RNA - amygdala [nTPM]":"12.3","Tissue RNA - appendix [nTPM]":"18.9","Tissue RNA - basal ganglia [nTPM]":"11.8","Tissue RNA - bone marrow [nTPM]":"12.4","Tissue RNA - breast [nTPM]":"22.7","Tissue RNA - cerebellum [nTPM]":"32.5","Tissue RNA - cerebral cortex [nTPM]":"14.0","Tissue RNA - cervix [nTPM]":"14.6","Tissue RNA - choroid plexus [nTPM]":"14.6","Tissue RNA - colon [nTPM]":"37.3","Tissue RNA - duodenum [nTPM]":"19.1","Tissue RNA - endometrium 1 [nTPM]":"13.5","Tissue RNA - epididymis [nTPM]":"38.5","Tissue RNA - esophagus [nTPM]":"26.3","Tissue RNA - fallopian tube [nTPM]":"12.9","Tissue RNA - gallbladder [nTPM]":"15.9","Tissue RNA - heart muscle [nTPM]":"19.8","Tissue RNA - hippocampal formation [nTPM]":"12.8","Tissue RNA - hypothalamus [nTPM]":"13.3","Tissue RNA - kidney [nTPM]":"25.5","Tissue RNA - liver [nTPM]":"22.0","Tissue RNA - lung [nTPM]":"13.9","Tissue RNA - lymph node [nTPM]":"17.6","Tissue RNA - medulla oblongata [nTPM]":"15.5","Tissue RNA - midbrain [nTPM]":"16.9","Tissue RNA - ovary [nTPM]":"11.4","Tissue RNA - pancreas [nTPM]":"18.5","Tissue RNA - parathyroid gland [nTPM]":"39.8","Tissue RNA - pituitary gland [nTPM]":"20.9","Tissue RNA - placenta [nTPM]":"12.6","Tissue RNA - pons [nTPM]":"18.8","Tissue RNA - prostate [nTPM]":"14.1","Tissue RNA - rectum [nTPM]":"38.8","Tissue RNA - retina [nTPM]":"37.8","Tissue RNA - salivary gland [nTPM]":"43.3","Tissue RNA - seminal vesicle [nTPM]":"14.0","Tissue RNA - skeletal muscle [nTPM]":"13.5","Tissue RNA - skin 1 [nTPM]":"21.2","Tissue RNA - small intestine [nTPM]":"18.2","Tissue RNA - smooth muscle [nTPM]":"18.4","Tissue RNA - spinal cord [nTPM]":"9.0","Tissue RNA - spleen [nTPM]":"14.1","Tissue RNA - stomach 1 [nTPM]":"23.3","Tissue RNA - testis [nTPM]":"12.3","Tissue RNA - thalamus [nTPM]":"14.1","Tissue RNA - thymus [nTPM]":"14.1","Tissue RNA - thyroid gland [nTPM]":"19.1","Tissue RNA - tongue [nTPM]":"11.8","Tissue RNA - tonsil [nTPM]":"20.8","Tissue RNA - urinary bladder [nTPM]":"18.1","Tissue RNA - vagina [nTPM]":"14.4","Tissue RNA - white matter [nTPM]":"12.2","Cell RNA - A-431 [nTPM]":"34.2","Cell RNA - A549 [nTPM]":"24.8","Cell RNA - AF22 [nTPM]":"20.6","Cell RNA - AN3-CA [nTPM]":"23.8","Cell RNA - ASC diff [nTPM]":"36.1","Cell RNA - ASC TERT1 [nTPM]":"28.2","Cell RNA - BEWO [nTPM]":"28.4","Cell RNA - BJ [nTPM]":"54.9","Cell RNA - BJ hTERT+ [nTPM]":"33.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"44.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"41.6","Cell RNA - CACO-2 [nTPM]":"37.4","Cell RNA - CAPAN-2 [nTPM]":"34.6","Cell RNA - Daudi [nTPM]":"38.4","Cell RNA - EFO-21 [nTPM]":"33.3","Cell RNA - fHDF\/TERT166 [nTPM]":"57.2","Cell RNA - GAMG [nTPM]":"30.0","Cell RNA - HaCaT [nTPM]":"24.1","Cell RNA - HAP1 [nTPM]":"25.4","Cell RNA - HBEC3-KT [nTPM]":"42.8","Cell RNA - HBF TERT88 [nTPM]":"42.9","Cell RNA - HDLM-2 [nTPM]":"22.7","Cell RNA - HEK 293 [nTPM]":"13.9","Cell RNA - HEL [nTPM]":"38.0","Cell RNA - HeLa [nTPM]":"66.9","Cell RNA - Hep G2 [nTPM]":"30.8","Cell RNA - HHSteC [nTPM]":"39.3","Cell RNA - HL-60 [nTPM]":"41.4","Cell RNA - HMC-1 [nTPM]":"51.5","Cell RNA - HSkMC [nTPM]":"40.3","Cell RNA - hTCEpi [nTPM]":"27.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"59.1","Cell RNA - hTERT-HME1 [nTPM]":"32.2","Cell RNA - hTERT-RPE1 [nTPM]":"29.4","Cell RNA - HUVEC TERT2 [nTPM]":"51.2","Cell RNA - JURKAT [nTPM]":"26.7","Cell RNA - K-562 [nTPM]":"27.3","Cell RNA - Karpas-707 [nTPM]":"41.0","Cell RNA - LHCN-M2 [nTPM]":"39.7","Cell RNA - MCF7 [nTPM]":"19.4","Cell RNA - MOLT-4 [nTPM]":"23.1","Cell RNA - NB-4 [nTPM]":"20.2","Cell RNA - NTERA-2 [nTPM]":"26.3","Cell RNA - OE19 [nTPM]":"53.1","Cell RNA - PC-3 [nTPM]":"36.2","Cell RNA - REH [nTPM]":"25.3","Cell RNA - RH-30 [nTPM]":"33.4","Cell RNA - RPMI-8226 [nTPM]":"31.2","Cell RNA - RPTEC TERT1 [nTPM]":"25.4","Cell RNA - RT4 [nTPM]":"28.8","Cell RNA - SCLC-21H [nTPM]":"24.4","Cell RNA - SH-SY5Y [nTPM]":"19.4","Cell RNA - SiHa [nTPM]":"36.4","Cell RNA - SK-BR-3 [nTPM]":"38.0","Cell RNA - SK-MEL-30 [nTPM]":"26.6","Cell RNA - SuSa [nTPM]":"26.8","Cell RNA - T-47d [nTPM]":"29.8","Cell RNA - THP-1 [nTPM]":"20.9","Cell RNA - TIME [nTPM]":"63.0","Cell RNA - U-138 MG [nTPM]":"30.1","Cell RNA - U-2 OS [nTPM]":"26.3","Cell RNA - U-2197 [nTPM]":"60.4","Cell RNA - U-251 MG [nTPM]":"32.0","Cell RNA - U-266\/70 [nTPM]":"48.1","Cell RNA - U-266\/84 [nTPM]":"72.4","Cell RNA - U-698 [nTPM]":"39.5","Cell RNA - U-87 MG [nTPM]":"43.0","Cell RNA - U-937 [nTPM]":"54.0","Cell RNA - WM-115 [nTPM]":"26.8","Blood RNA - basophil [nTPM]":"9.4","Blood RNA - classical monocyte [nTPM]":"16.1","Blood RNA - eosinophil [nTPM]":"9.6","Blood RNA - gdT-cell [nTPM]":"13.8","Blood RNA - intermediate monocyte [nTPM]":"23.6","Blood RNA - MAIT T-cell [nTPM]":"9.8","Blood RNA - memory B-cell [nTPM]":"13.2","Blood RNA - memory CD4 T-cell [nTPM]":"9.0","Blood RNA - memory CD8 T-cell [nTPM]":"9.1","Blood RNA - myeloid DC [nTPM]":"13.6","Blood RNA - naive B-cell [nTPM]":"10.2","Blood RNA - naive CD4 T-cell [nTPM]":"7.4","Blood RNA - naive CD8 T-cell [nTPM]":"10.9","Blood RNA - neutrophil [nTPM]":"13.0","Blood RNA - NK-cell [nTPM]":"10.1","Blood RNA - non-classical monocyte [nTPM]":"23.1","Blood RNA - plasmacytoid DC [nTPM]":"11.5","Blood RNA - T-reg [nTPM]":"8.3","Blood RNA - total PBMC [nTPM]":"10.5","Brain RNA - amygdala [nTPM]":"12.3","Brain RNA - basal ganglia [nTPM]":"11.8","Brain RNA - cerebellum [nTPM]":"32.5","Brain RNA - cerebral cortex [nTPM]":"14.0","Brain RNA - hippocampal formation [nTPM]":"12.8","Brain RNA - hypothalamus [nTPM]":"13.3","Brain RNA - medulla oblongata [nTPM]":"15.5","Brain RNA - midbrain [nTPM]":"16.9","Brain RNA - pons [nTPM]":"18.8","Brain RNA - spinal cord [nTPM]":"9.0","Brain RNA - thalamus [nTPM]":"14.1","Brain RNA - white matter [nTPM]":"12.2","Single Cell Type RNA - Adipocytes [nTPM]":"9.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.8","Single Cell Type RNA - Astrocytes [nTPM]":"7.8","Single Cell Type RNA - B-cells [nTPM]":"13.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"29.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"13.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"256.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.3","Single Cell Type RNA - dendritic cells [nTPM]":"13.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"76.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"19.3","Single Cell Type RNA - Early spermatids [nTPM]":"99.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.9","Single Cell Type RNA - Endothelial cells [nTPM]":"11.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.9","Single Cell Type RNA - Erythroid cells [nTPM]":"5.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"26.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"23.4","Single Cell Type RNA - Fibroblasts [nTPM]":"11.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"33.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.0","Single Cell Type RNA - granulocytes [nTPM]":"19.0","Single Cell Type RNA - Granulosa cells [nTPM]":"14.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.0","Single Cell Type RNA - Hepatocytes [nTPM]":"13.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.5","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"28.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"46.3","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"11.5","Single Cell Type RNA - Langerhans cells [nTPM]":"7.1","Single Cell Type RNA - Late spermatids [nTPM]":"23.4","Single Cell Type RNA - Leydig cells [nTPM]":"10.5","Single Cell Type RNA - Macrophages [nTPM]":"10.5","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"34.4","Single Cell Type RNA - Muller glia cells [nTPM]":"16.3","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.6","Single Cell Type RNA - Paneth cells [nTPM]":"40.3","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"18.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"29.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"106.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.5","Single Cell Type RNA - Spermatocytes [nTPM]":"13.2","Single Cell Type RNA - Spermatogonia [nTPM]":"13.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"25.4","Single Cell Type RNA - T-cells [nTPM]":"10.3","Single Cell Type RNA - Theca cells [nTPM]":"15.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.0","Single Cell Type RNA - Urothelial cells [nTPM]":"12.2"},{"Gene":"DHPS","Gene synonym":["MIG13"],"Ensembl":"ENSG00000095059","Gene description":"Deoxyhypusine synthase","Uniprot":["P49366"],"Chromosome":"19","Position":"12675717-12681880","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Hypusine biosynthesis"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014461","HPA029413"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA014461":"AB_1847651","HPA029413":"AB_10602217"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Tissue RNA - adipose tissue [nTPM]":"30.6","Tissue RNA - adrenal gland [nTPM]":"43.2","Tissue RNA - amygdala [nTPM]":"44.6","Tissue RNA - appendix [nTPM]":"23.9","Tissue RNA - basal ganglia [nTPM]":"48.1","Tissue RNA - bone marrow [nTPM]":"21.7","Tissue RNA - breast [nTPM]":"29.6","Tissue RNA - cerebellum [nTPM]":"51.0","Tissue RNA - cerebral cortex [nTPM]":"57.5","Tissue RNA - cervix [nTPM]":"35.7","Tissue RNA - choroid plexus [nTPM]":"50.0","Tissue RNA - colon [nTPM]":"40.9","Tissue RNA - duodenum [nTPM]":"28.0","Tissue RNA - endometrium 1 [nTPM]":"33.2","Tissue RNA - epididymis [nTPM]":"15.6","Tissue RNA - esophagus [nTPM]":"29.5","Tissue RNA - fallopian tube [nTPM]":"38.6","Tissue RNA - gallbladder [nTPM]":"20.1","Tissue RNA - heart muscle [nTPM]":"41.0","Tissue RNA - hippocampal formation [nTPM]":"46.5","Tissue RNA - hypothalamus [nTPM]":"48.6","Tissue RNA - kidney [nTPM]":"34.2","Tissue RNA - liver [nTPM]":"41.0","Tissue RNA - lung [nTPM]":"29.6","Tissue RNA - lymph node [nTPM]":"32.7","Tissue RNA - medulla oblongata [nTPM]":"46.4","Tissue RNA - midbrain [nTPM]":"45.1","Tissue RNA - ovary [nTPM]":"40.6","Tissue RNA - pancreas [nTPM]":"49.7","Tissue RNA - parathyroid gland [nTPM]":"47.0","Tissue RNA - pituitary gland [nTPM]":"52.8","Tissue RNA - placenta [nTPM]":"19.7","Tissue RNA - pons [nTPM]":"50.0","Tissue RNA - prostate [nTPM]":"34.8","Tissue RNA - rectum [nTPM]":"29.5","Tissue RNA - retina [nTPM]":"69.1","Tissue RNA - salivary gland [nTPM]":"34.1","Tissue RNA - seminal vesicle [nTPM]":"27.9","Tissue RNA - skeletal muscle [nTPM]":"92.6","Tissue RNA - skin 1 [nTPM]":"41.3","Tissue RNA - small intestine [nTPM]":"32.8","Tissue RNA - smooth muscle [nTPM]":"29.1","Tissue RNA - spinal cord [nTPM]":"47.7","Tissue RNA - spleen [nTPM]":"31.6","Tissue RNA - stomach 1 [nTPM]":"44.2","Tissue RNA - testis [nTPM]":"16.0","Tissue RNA - thalamus [nTPM]":"45.9","Tissue RNA - thymus [nTPM]":"45.2","Tissue RNA - thyroid gland [nTPM]":"28.7","Tissue RNA - tongue [nTPM]":"70.5","Tissue RNA - tonsil [nTPM]":"34.7","Tissue RNA - urinary bladder [nTPM]":"36.7","Tissue RNA - vagina [nTPM]":"33.1","Tissue RNA - white matter [nTPM]":"56.2","Cell RNA - A-431 [nTPM]":"70.8","Cell RNA - A549 [nTPM]":"50.8","Cell RNA - AF22 [nTPM]":"80.8","Cell RNA - AN3-CA [nTPM]":"41.5","Cell RNA - ASC diff [nTPM]":"34.2","Cell RNA - ASC TERT1 [nTPM]":"57.7","Cell RNA - BEWO [nTPM]":"18.6","Cell RNA - BJ [nTPM]":"44.0","Cell RNA - BJ hTERT+ [nTPM]":"64.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"82.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"82.9","Cell RNA - CACO-2 [nTPM]":"35.4","Cell RNA - CAPAN-2 [nTPM]":"33.8","Cell RNA - Daudi [nTPM]":"71.7","Cell RNA - EFO-21 [nTPM]":"49.4","Cell RNA - fHDF\/TERT166 [nTPM]":"48.2","Cell RNA - GAMG [nTPM]":"75.6","Cell RNA - HaCaT [nTPM]":"41.0","Cell RNA - HAP1 [nTPM]":"55.7","Cell RNA - HBEC3-KT [nTPM]":"63.0","Cell RNA - HBF TERT88 [nTPM]":"57.4","Cell RNA - HDLM-2 [nTPM]":"64.2","Cell RNA - HEK 293 [nTPM]":"37.8","Cell RNA - HEL [nTPM]":"48.8","Cell RNA - HeLa [nTPM]":"51.4","Cell RNA - Hep G2 [nTPM]":"47.1","Cell RNA - HHSteC [nTPM]":"43.8","Cell RNA - HL-60 [nTPM]":"57.2","Cell RNA - HMC-1 [nTPM]":"72.1","Cell RNA - HSkMC [nTPM]":"47.2","Cell RNA - hTCEpi [nTPM]":"74.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"49.7","Cell RNA - hTERT-HME1 [nTPM]":"85.2","Cell RNA - hTERT-RPE1 [nTPM]":"82.9","Cell RNA - HUVEC TERT2 [nTPM]":"59.1","Cell RNA - JURKAT [nTPM]":"141.5","Cell RNA - K-562 [nTPM]":"45.1","Cell RNA - Karpas-707 [nTPM]":"49.5","Cell RNA - LHCN-M2 [nTPM]":"61.5","Cell RNA - MCF7 [nTPM]":"137.0","Cell RNA - MOLT-4 [nTPM]":"105.1","Cell RNA - NB-4 [nTPM]":"83.3","Cell RNA - NTERA-2 [nTPM]":"64.2","Cell RNA - OE19 [nTPM]":"90.3","Cell RNA - PC-3 [nTPM]":"85.1","Cell RNA - REH [nTPM]":"65.8","Cell RNA - RH-30 [nTPM]":"29.1","Cell RNA - RPMI-8226 [nTPM]":"106.6","Cell RNA - RPTEC TERT1 [nTPM]":"63.5","Cell RNA - RT4 [nTPM]":"34.6","Cell RNA - SCLC-21H [nTPM]":"106.7","Cell RNA - SH-SY5Y [nTPM]":"144.4","Cell RNA - SiHa [nTPM]":"44.0","Cell RNA - SK-BR-3 [nTPM]":"64.2","Cell RNA - SK-MEL-30 [nTPM]":"76.0","Cell RNA - SuSa [nTPM]":"48.1","Cell RNA - T-47d [nTPM]":"59.0","Cell RNA - THP-1 [nTPM]":"96.5","Cell RNA - TIME [nTPM]":"29.8","Cell RNA - U-138 MG [nTPM]":"94.4","Cell RNA - U-2 OS [nTPM]":"38.2","Cell RNA - U-2197 [nTPM]":"93.5","Cell RNA - U-251 MG [nTPM]":"69.2","Cell RNA - U-266\/70 [nTPM]":"160.0","Cell RNA - U-266\/84 [nTPM]":"184.9","Cell RNA - U-698 [nTPM]":"49.9","Cell RNA - U-87 MG [nTPM]":"59.7","Cell RNA - U-937 [nTPM]":"66.2","Cell RNA - WM-115 [nTPM]":"94.5","Blood RNA - basophil [nTPM]":"37.0","Blood RNA - classical monocyte [nTPM]":"58.8","Blood RNA - eosinophil [nTPM]":"82.7","Blood RNA - gdT-cell [nTPM]":"51.0","Blood RNA - intermediate monocyte [nTPM]":"54.1","Blood RNA - MAIT T-cell [nTPM]":"53.0","Blood RNA - memory B-cell [nTPM]":"86.2","Blood RNA - memory CD4 T-cell [nTPM]":"59.0","Blood RNA - memory CD8 T-cell [nTPM]":"52.8","Blood RNA - myeloid DC [nTPM]":"63.4","Blood RNA - naive B-cell [nTPM]":"82.1","Blood RNA - naive CD4 T-cell [nTPM]":"77.7","Blood RNA - naive CD8 T-cell [nTPM]":"56.8","Blood RNA - neutrophil [nTPM]":"18.2","Blood RNA - NK-cell [nTPM]":"64.2","Blood RNA - non-classical monocyte [nTPM]":"72.8","Blood RNA - plasmacytoid DC [nTPM]":"64.9","Blood RNA - T-reg [nTPM]":"77.6","Blood RNA - total PBMC [nTPM]":"70.0","Brain RNA - amygdala [nTPM]":"44.6","Brain RNA - basal ganglia [nTPM]":"48.1","Brain RNA - cerebellum [nTPM]":"51.0","Brain RNA - cerebral cortex [nTPM]":"57.5","Brain RNA - hippocampal formation [nTPM]":"46.5","Brain RNA - hypothalamus [nTPM]":"48.6","Brain RNA - medulla oblongata [nTPM]":"46.4","Brain RNA - midbrain [nTPM]":"45.1","Brain RNA - pons [nTPM]":"50.0","Brain RNA - spinal cord [nTPM]":"47.7","Brain RNA - thalamus [nTPM]":"45.9","Brain RNA - white matter [nTPM]":"56.2","Single Cell Type RNA - Adipocytes [nTPM]":"40.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"30.7","Single Cell Type RNA - Astrocytes [nTPM]":"10.1","Single Cell Type RNA - B-cells [nTPM]":"54.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"55.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"79.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"93.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"38.7","Single Cell Type RNA - Bipolar cells [nTPM]":"75.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"48.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"64.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"37.1","Single Cell Type RNA - Club cells [nTPM]":"49.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"47.1","Single Cell Type RNA - dendritic cells [nTPM]":"52.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"35.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"86.1","Single Cell Type RNA - Ductal cells [nTPM]":"53.7","Single Cell Type RNA - Early spermatids [nTPM]":"20.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"38.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"24.5","Single Cell Type RNA - Endothelial cells [nTPM]":"35.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"41.3","Single Cell Type RNA - Erythroid cells [nTPM]":"26.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"37.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"55.1","Single Cell Type RNA - Fibroblasts [nTPM]":"35.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"33.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"27.9","Single Cell Type RNA - granulocytes [nTPM]":"24.1","Single Cell Type RNA - Granulosa cells [nTPM]":"46.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"30.4","Single Cell Type RNA - Hepatocytes [nTPM]":"34.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"42.8","Single Cell Type RNA - Horizontal cells [nTPM]":"42.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"60.8","Single Cell Type RNA - Ionocytes [nTPM]":"79.3","Single Cell Type RNA - Kupffer cells [nTPM]":"37.6","Single Cell Type RNA - Langerhans cells [nTPM]":"42.5","Single Cell Type RNA - Late spermatids [nTPM]":"27.5","Single Cell Type RNA - Leydig cells [nTPM]":"45.1","Single Cell Type RNA - Macrophages [nTPM]":"35.3","Single Cell Type RNA - Melanocytes [nTPM]":"49.8","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"62.7","Single Cell Type RNA - Muller glia cells [nTPM]":"115.2","Single Cell Type RNA - NK-cells [nTPM]":"53.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"48.7","Single Cell Type RNA - Paneth cells [nTPM]":"70.1","Single Cell Type RNA - Peritubular cells [nTPM]":"34.6","Single Cell Type RNA - Plasma cells [nTPM]":"51.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"73.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"87.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"84.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"49.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"129.2","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"39.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"53.8","Single Cell Type RNA - Spermatocytes [nTPM]":"33.3","Single Cell Type RNA - Spermatogonia [nTPM]":"62.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"39.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"51.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"71.8","Single Cell Type RNA - T-cells [nTPM]":"51.1","Single Cell Type RNA - Theca cells [nTPM]":"37.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"54.3","Single Cell Type RNA - Urothelial cells [nTPM]":"71.0"},{"Gene":"DHTKD1","Gene synonym":["CMT2Q","DKFZP762M115","KIAA1630","MGC3090"],"Ensembl":"ENSG00000181192","Gene description":"Dehydrogenase E1 and transketolase domain containing 1","Uniprot":["Q96HY7"],"Chromosome":"10","Position":"12068954-12123221","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Glycolysis"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"129.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"227.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"T-47d":"102.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037949","HPA037950","HPA066098"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA037949":"AB_2675752","HPA037950":"AB_10673650","HPA066098":"AB_2685617"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.43e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-3"},"Tissue RNA - adipose tissue [nTPM]":"10.7","Tissue RNA - adrenal gland [nTPM]":"8.4","Tissue RNA - amygdala [nTPM]":"8.1","Tissue RNA - appendix [nTPM]":"6.8","Tissue RNA - basal ganglia [nTPM]":"10.4","Tissue RNA - bone marrow [nTPM]":"3.8","Tissue RNA - breast [nTPM]":"8.4","Tissue RNA - cerebellum [nTPM]":"12.6","Tissue RNA - cerebral cortex [nTPM]":"8.5","Tissue RNA - cervix [nTPM]":"8.8","Tissue RNA - choroid plexus [nTPM]":"11.9","Tissue RNA - colon [nTPM]":"10.1","Tissue RNA - duodenum [nTPM]":"7.6","Tissue RNA - endometrium 1 [nTPM]":"6.2","Tissue RNA - epididymis [nTPM]":"6.8","Tissue RNA - esophagus [nTPM]":"7.5","Tissue RNA - fallopian tube [nTPM]":"6.1","Tissue RNA - gallbladder [nTPM]":"5.3","Tissue RNA - heart muscle [nTPM]":"13.2","Tissue RNA - hippocampal formation [nTPM]":"7.6","Tissue RNA - hypothalamus [nTPM]":"8.5","Tissue RNA - kidney [nTPM]":"42.7","Tissue RNA - liver [nTPM]":"129.5","Tissue RNA - lung [nTPM]":"5.4","Tissue RNA - lymph node [nTPM]":"8.5","Tissue RNA - medulla oblongata [nTPM]":"9.5","Tissue RNA - midbrain [nTPM]":"8.6","Tissue RNA - ovary [nTPM]":"10.0","Tissue RNA - pancreas [nTPM]":"18.0","Tissue RNA - parathyroid gland [nTPM]":"12.7","Tissue RNA - pituitary gland [nTPM]":"5.6","Tissue RNA - placenta [nTPM]":"7.7","Tissue RNA - pons [nTPM]":"9.5","Tissue RNA - prostate [nTPM]":"12.9","Tissue RNA - rectum [nTPM]":"10.8","Tissue RNA - retina [nTPM]":"7.5","Tissue RNA - salivary gland [nTPM]":"13.1","Tissue RNA - seminal vesicle [nTPM]":"5.7","Tissue RNA - skeletal muscle [nTPM]":"18.7","Tissue RNA - skin 1 [nTPM]":"5.6","Tissue RNA - small intestine [nTPM]":"6.9","Tissue RNA - smooth muscle [nTPM]":"5.7","Tissue RNA - spinal cord [nTPM]":"8.8","Tissue RNA - spleen [nTPM]":"7.8","Tissue RNA - stomach 1 [nTPM]":"10.9","Tissue RNA - testis [nTPM]":"4.7","Tissue RNA - thalamus [nTPM]":"9.1","Tissue RNA - thymus [nTPM]":"10.5","Tissue RNA - thyroid gland [nTPM]":"11.6","Tissue RNA - tongue [nTPM]":"23.1","Tissue RNA - tonsil [nTPM]":"9.7","Tissue RNA - urinary bladder [nTPM]":"6.3","Tissue RNA - vagina [nTPM]":"6.1","Tissue RNA - white matter [nTPM]":"11.4","Cell RNA - A-431 [nTPM]":"27.0","Cell RNA - A549 [nTPM]":"20.4","Cell RNA - AF22 [nTPM]":"29.8","Cell RNA - AN3-CA [nTPM]":"23.8","Cell RNA - ASC diff [nTPM]":"18.2","Cell RNA - ASC TERT1 [nTPM]":"10.8","Cell RNA - BEWO [nTPM]":"35.9","Cell RNA - BJ [nTPM]":"13.3","Cell RNA - BJ hTERT+ [nTPM]":"8.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.6","Cell RNA - CACO-2 [nTPM]":"13.1","Cell RNA - CAPAN-2 [nTPM]":"15.7","Cell RNA - Daudi [nTPM]":"19.3","Cell RNA - EFO-21 [nTPM]":"4.3","Cell RNA - fHDF\/TERT166 [nTPM]":"8.4","Cell RNA - GAMG [nTPM]":"10.8","Cell RNA - HaCaT [nTPM]":"37.4","Cell RNA - HAP1 [nTPM]":"31.6","Cell RNA - HBEC3-KT [nTPM]":"10.4","Cell RNA - HBF TERT88 [nTPM]":"26.6","Cell RNA - HDLM-2 [nTPM]":"10.9","Cell RNA - HEK 293 [nTPM]":"14.2","Cell RNA - HEL [nTPM]":"10.6","Cell RNA - HeLa [nTPM]":"7.7","Cell RNA - Hep G2 [nTPM]":"10.1","Cell RNA - HHSteC [nTPM]":"17.8","Cell RNA - HL-60 [nTPM]":"4.2","Cell RNA - HMC-1 [nTPM]":"3.8","Cell RNA - HSkMC [nTPM]":"13.3","Cell RNA - hTCEpi [nTPM]":"7.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.7","Cell RNA - hTERT-HME1 [nTPM]":"5.5","Cell RNA - hTERT-RPE1 [nTPM]":"9.2","Cell RNA - HUVEC TERT2 [nTPM]":"13.0","Cell RNA - JURKAT [nTPM]":"23.1","Cell RNA - K-562 [nTPM]":"16.7","Cell RNA - Karpas-707 [nTPM]":"15.1","Cell RNA - LHCN-M2 [nTPM]":"6.3","Cell RNA - MCF7 [nTPM]":"52.3","Cell RNA - MOLT-4 [nTPM]":"14.4","Cell RNA - NB-4 [nTPM]":"7.7","Cell RNA - NTERA-2 [nTPM]":"16.7","Cell RNA - OE19 [nTPM]":"24.9","Cell RNA - PC-3 [nTPM]":"4.7","Cell RNA - REH [nTPM]":"24.3","Cell RNA - RH-30 [nTPM]":"9.7","Cell RNA - RPMI-8226 [nTPM]":"16.5","Cell RNA - RPTEC TERT1 [nTPM]":"15.2","Cell RNA - RT4 [nTPM]":"6.4","Cell RNA - SCLC-21H [nTPM]":"7.7","Cell RNA - SH-SY5Y [nTPM]":"34.9","Cell RNA - SiHa [nTPM]":"26.3","Cell RNA - SK-BR-3 [nTPM]":"46.3","Cell RNA - SK-MEL-30 [nTPM]":"15.4","Cell RNA - SuSa [nTPM]":"31.7","Cell RNA - T-47d [nTPM]":"102.2","Cell RNA - THP-1 [nTPM]":"15.2","Cell RNA - TIME [nTPM]":"5.8","Cell RNA - U-138 MG [nTPM]":"7.5","Cell RNA - U-2 OS [nTPM]":"5.4","Cell RNA - U-2197 [nTPM]":"15.8","Cell RNA - U-251 MG [nTPM]":"9.9","Cell RNA - U-266\/70 [nTPM]":"13.4","Cell RNA - U-266\/84 [nTPM]":"10.3","Cell RNA - U-698 [nTPM]":"12.6","Cell RNA - U-87 MG [nTPM]":"9.7","Cell RNA - U-937 [nTPM]":"7.4","Cell RNA - WM-115 [nTPM]":"12.8","Blood RNA - basophil [nTPM]":"23.8","Blood RNA - classical monocyte [nTPM]":"6.8","Blood RNA - eosinophil [nTPM]":"15.4","Blood RNA - gdT-cell [nTPM]":"4.2","Blood RNA - intermediate monocyte [nTPM]":"9.2","Blood RNA - MAIT T-cell [nTPM]":"4.5","Blood RNA - memory B-cell [nTPM]":"13.0","Blood RNA - memory CD4 T-cell [nTPM]":"3.2","Blood RNA - memory CD8 T-cell [nTPM]":"2.7","Blood RNA - myeloid DC [nTPM]":"11.9","Blood RNA - naive B-cell [nTPM]":"9.9","Blood RNA - naive CD4 T-cell [nTPM]":"3.1","Blood RNA - naive CD8 T-cell [nTPM]":"4.1","Blood RNA - neutrophil [nTPM]":"19.4","Blood RNA - NK-cell [nTPM]":"14.3","Blood RNA - non-classical monocyte [nTPM]":"17.0","Blood RNA - plasmacytoid DC [nTPM]":"17.3","Blood RNA - T-reg [nTPM]":"5.7","Blood RNA - total PBMC [nTPM]":"4.9","Brain RNA - amygdala [nTPM]":"8.1","Brain RNA - basal ganglia [nTPM]":"10.4","Brain RNA - cerebellum [nTPM]":"12.6","Brain RNA - cerebral cortex [nTPM]":"8.5","Brain RNA - hippocampal formation [nTPM]":"7.6","Brain RNA - hypothalamus [nTPM]":"8.5","Brain RNA - medulla oblongata [nTPM]":"9.5","Brain RNA - midbrain [nTPM]":"8.6","Brain RNA - pons [nTPM]":"9.5","Brain RNA - spinal cord [nTPM]":"8.8","Brain RNA - thalamus [nTPM]":"9.1","Brain RNA - white matter [nTPM]":"11.4","Single Cell Type RNA - Adipocytes [nTPM]":"6.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"38.8","Single Cell Type RNA - Astrocytes [nTPM]":"21.5","Single Cell Type RNA - B-cells [nTPM]":"21.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"13.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"31.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"28.6","Single Cell Type RNA - Club cells [nTPM]":"7.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"35.4","Single Cell Type RNA - dendritic cells [nTPM]":"23.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"10.9","Single Cell Type RNA - Early spermatids [nTPM]":"3.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.3","Single Cell Type RNA - Endothelial cells [nTPM]":"8.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.3","Single Cell Type RNA - Erythroid cells [nTPM]":"21.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"25.1","Single Cell Type RNA - Fibroblasts [nTPM]":"8.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.8","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"45.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"227.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.3","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"15.3","Single Cell Type RNA - Langerhans cells [nTPM]":"10.1","Single Cell Type RNA - Late spermatids [nTPM]":"4.2","Single Cell Type RNA - Leydig cells [nTPM]":"12.5","Single Cell Type RNA - Macrophages [nTPM]":"13.5","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"13.4","Single Cell Type RNA - Muller glia cells [nTPM]":"10.4","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.4","Single Cell Type RNA - Paneth cells [nTPM]":"9.6","Single Cell Type RNA - Peritubular cells [nTPM]":"12.0","Single Cell Type RNA - Plasma cells [nTPM]":"22.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"62.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.4","Single Cell Type RNA - Spermatocytes [nTPM]":"6.7","Single Cell Type RNA - Spermatogonia [nTPM]":"3.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"13.5","Single Cell Type RNA - T-cells [nTPM]":"8.4","Single Cell Type RNA - Theca cells [nTPM]":"21.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.6","Single Cell Type RNA - Urothelial cells [nTPM]":"7.8"},{"Gene":"DHX16","Gene synonym":["DBP2","DDX16","Prp2","PRPF2"],"Ensembl":"ENSG00000204560","Gene description":"DEAH-box helicase 16","Uniprot":["O60231"],"Chromosome":"6","Position":"30653119-30673006","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":["Helicase","Hydrolase"],"Disease involvement":["Disease variant","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"92.7","Spermatocytes":"86.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051455"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA051455":"AB_2681491"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-3"},"Tissue RNA - adipose tissue [nTPM]":"24.3","Tissue RNA - adrenal gland [nTPM]":"28.2","Tissue RNA - amygdala [nTPM]":"5.4","Tissue RNA - appendix [nTPM]":"13.8","Tissue RNA - basal ganglia [nTPM]":"6.3","Tissue RNA - bone marrow [nTPM]":"11.3","Tissue RNA - breast [nTPM]":"26.0","Tissue RNA - cerebellum [nTPM]":"6.3","Tissue RNA - cerebral cortex [nTPM]":"6.8","Tissue RNA - cervix [nTPM]":"27.7","Tissue RNA - choroid plexus [nTPM]":"8.3","Tissue RNA - colon [nTPM]":"29.5","Tissue RNA - duodenum [nTPM]":"18.8","Tissue RNA - endometrium 1 [nTPM]":"25.5","Tissue RNA - epididymis [nTPM]":"8.6","Tissue RNA - esophagus [nTPM]":"27.2","Tissue RNA - fallopian tube [nTPM]":"26.6","Tissue RNA - gallbladder [nTPM]":"11.3","Tissue RNA - heart muscle [nTPM]":"26.6","Tissue RNA - hippocampal formation [nTPM]":"5.3","Tissue RNA - hypothalamus [nTPM]":"6.0","Tissue RNA - kidney [nTPM]":"34.9","Tissue RNA - liver [nTPM]":"36.5","Tissue RNA - lung [nTPM]":"25.4","Tissue RNA - lymph node [nTPM]":"18.1","Tissue RNA - medulla oblongata [nTPM]":"6.3","Tissue RNA - midbrain [nTPM]":"5.9","Tissue RNA - ovary [nTPM]":"26.2","Tissue RNA - pancreas [nTPM]":"35.0","Tissue RNA - parathyroid gland [nTPM]":"16.0","Tissue RNA - pituitary gland [nTPM]":"28.6","Tissue RNA - placenta [nTPM]":"10.5","Tissue RNA - pons [nTPM]":"6.4","Tissue RNA - prostate [nTPM]":"30.1","Tissue RNA - rectum [nTPM]":"10.3","Tissue RNA - retina [nTPM]":"14.4","Tissue RNA - salivary gland [nTPM]":"32.0","Tissue RNA - seminal vesicle [nTPM]":"12.8","Tissue RNA - skeletal muscle [nTPM]":"45.0","Tissue RNA - skin 1 [nTPM]":"28.8","Tissue RNA - small intestine [nTPM]":"37.5","Tissue RNA - smooth muscle [nTPM]":"12.5","Tissue RNA - spinal cord [nTPM]":"5.2","Tissue RNA - spleen [nTPM]":"40.3","Tissue RNA - stomach 1 [nTPM]":"28.3","Tissue RNA - testis [nTPM]":"46.8","Tissue RNA - thalamus [nTPM]":"6.6","Tissue RNA - thymus [nTPM]":"17.1","Tissue RNA - thyroid gland [nTPM]":"38.2","Tissue RNA - tongue [nTPM]":"17.6","Tissue RNA - tonsil [nTPM]":"12.7","Tissue RNA - urinary bladder [nTPM]":"24.8","Tissue RNA - vagina [nTPM]":"26.8","Tissue RNA - white matter [nTPM]":"6.4","Cell RNA - A-431 [nTPM]":"31.9","Cell RNA - A549 [nTPM]":"17.9","Cell RNA - AF22 [nTPM]":"20.3","Cell RNA - AN3-CA [nTPM]":"38.7","Cell RNA - ASC diff [nTPM]":"26.8","Cell RNA - ASC TERT1 [nTPM]":"15.7","Cell RNA - BEWO [nTPM]":"27.0","Cell RNA - BJ [nTPM]":"33.0","Cell RNA - BJ hTERT+ [nTPM]":"30.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"47.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"44.3","Cell RNA - CACO-2 [nTPM]":"35.8","Cell RNA - CAPAN-2 [nTPM]":"15.9","Cell RNA - Daudi [nTPM]":"25.5","Cell RNA - EFO-21 [nTPM]":"24.2","Cell RNA - fHDF\/TERT166 [nTPM]":"31.1","Cell RNA - GAMG [nTPM]":"39.6","Cell RNA - HaCaT [nTPM]":"34.0","Cell RNA - HAP1 [nTPM]":"47.0","Cell RNA - HBEC3-KT [nTPM]":"24.1","Cell RNA - HBF TERT88 [nTPM]":"35.5","Cell RNA - HDLM-2 [nTPM]":"35.4","Cell RNA - HEK 293 [nTPM]":"15.5","Cell RNA - HEL [nTPM]":"27.2","Cell RNA - HeLa [nTPM]":"25.5","Cell RNA - Hep G2 [nTPM]":"17.9","Cell RNA - HHSteC [nTPM]":"21.4","Cell RNA - HL-60 [nTPM]":"65.9","Cell RNA - HMC-1 [nTPM]":"40.4","Cell RNA - HSkMC [nTPM]":"17.6","Cell RNA - hTCEpi [nTPM]":"22.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"47.3","Cell RNA - hTERT-HME1 [nTPM]":"30.1","Cell RNA - hTERT-RPE1 [nTPM]":"16.5","Cell RNA - HUVEC TERT2 [nTPM]":"16.9","Cell RNA - JURKAT [nTPM]":"36.9","Cell RNA - K-562 [nTPM]":"44.4","Cell RNA - Karpas-707 [nTPM]":"29.3","Cell RNA - LHCN-M2 [nTPM]":"26.7","Cell RNA - MCF7 [nTPM]":"29.0","Cell RNA - MOLT-4 [nTPM]":"22.4","Cell RNA - NB-4 [nTPM]":"20.8","Cell RNA - NTERA-2 [nTPM]":"21.4","Cell RNA - OE19 [nTPM]":"20.9","Cell RNA - PC-3 [nTPM]":"12.1","Cell RNA - REH [nTPM]":"38.5","Cell RNA - RH-30 [nTPM]":"17.4","Cell RNA - RPMI-8226 [nTPM]":"28.2","Cell RNA - RPTEC TERT1 [nTPM]":"18.4","Cell RNA - RT4 [nTPM]":"24.0","Cell RNA - SCLC-21H [nTPM]":"27.9","Cell RNA - SH-SY5Y [nTPM]":"19.7","Cell RNA - SiHa [nTPM]":"30.8","Cell RNA - SK-BR-3 [nTPM]":"37.4","Cell RNA - SK-MEL-30 [nTPM]":"32.0","Cell RNA - SuSa [nTPM]":"20.3","Cell RNA - T-47d [nTPM]":"29.5","Cell RNA - THP-1 [nTPM]":"24.7","Cell RNA - TIME [nTPM]":"11.8","Cell RNA - U-138 MG [nTPM]":"31.2","Cell RNA - U-2 OS [nTPM]":"21.3","Cell RNA - U-2197 [nTPM]":"27.4","Cell RNA - U-251 MG [nTPM]":"46.3","Cell RNA - U-266\/70 [nTPM]":"29.9","Cell RNA - U-266\/84 [nTPM]":"49.9","Cell RNA - U-698 [nTPM]":"20.2","Cell RNA - U-87 MG [nTPM]":"15.7","Cell RNA - U-937 [nTPM]":"36.8","Cell RNA - WM-115 [nTPM]":"40.4","Blood RNA - basophil [nTPM]":"10.5","Blood RNA - classical monocyte [nTPM]":"11.2","Blood RNA - eosinophil [nTPM]":"18.6","Blood RNA - gdT-cell [nTPM]":"7.4","Blood RNA - intermediate monocyte [nTPM]":"14.7","Blood RNA - MAIT T-cell [nTPM]":"9.5","Blood RNA - memory B-cell [nTPM]":"7.7","Blood RNA - memory CD4 T-cell [nTPM]":"9.1","Blood RNA - memory CD8 T-cell [nTPM]":"7.9","Blood RNA - myeloid DC [nTPM]":"11.1","Blood RNA - naive B-cell [nTPM]":"5.9","Blood RNA - naive CD4 T-cell [nTPM]":"7.4","Blood RNA - naive CD8 T-cell [nTPM]":"5.8","Blood RNA - neutrophil [nTPM]":"11.4","Blood RNA - NK-cell [nTPM]":"14.8","Blood RNA - non-classical monocyte [nTPM]":"16.4","Blood RNA - plasmacytoid DC [nTPM]":"9.8","Blood RNA - T-reg [nTPM]":"7.4","Blood RNA - total PBMC [nTPM]":"7.5","Brain RNA - amygdala [nTPM]":"5.4","Brain RNA - basal ganglia [nTPM]":"6.3","Brain RNA - cerebellum [nTPM]":"6.3","Brain RNA - cerebral cortex [nTPM]":"6.8","Brain RNA - hippocampal formation [nTPM]":"5.3","Brain RNA - hypothalamus [nTPM]":"6.0","Brain RNA - medulla oblongata [nTPM]":"6.3","Brain RNA - midbrain [nTPM]":"5.9","Brain RNA - pons [nTPM]":"6.4","Brain RNA - spinal cord [nTPM]":"5.2","Brain RNA - thalamus [nTPM]":"6.6","Brain RNA - white matter [nTPM]":"6.4","Single Cell Type RNA - Adipocytes [nTPM]":"13.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.9","Single Cell Type RNA - Astrocytes [nTPM]":"4.6","Single Cell Type RNA - B-cells [nTPM]":"16.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"16.5","Single Cell Type RNA - Bipolar cells [nTPM]":"13.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"20.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.2","Single Cell Type RNA - dendritic cells [nTPM]":"14.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"15.7","Single Cell Type RNA - Early spermatids [nTPM]":"92.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.0","Single Cell Type RNA - Endothelial cells [nTPM]":"11.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"14.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.1","Single Cell Type RNA - Fibroblasts [nTPM]":"11.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"26.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.8","Single Cell Type RNA - granulocytes [nTPM]":"42.3","Single Cell Type RNA - Granulosa cells [nTPM]":"11.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.6","Single Cell Type RNA - Hepatocytes [nTPM]":"9.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.9","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.6","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"12.6","Single Cell Type RNA - Langerhans cells [nTPM]":"12.8","Single Cell Type RNA - Late spermatids [nTPM]":"49.3","Single Cell Type RNA - Leydig cells [nTPM]":"14.3","Single Cell Type RNA - Macrophages [nTPM]":"14.4","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"20.3","Single Cell Type RNA - Muller glia cells [nTPM]":"11.6","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.9","Single Cell Type RNA - Paneth cells [nTPM]":"23.1","Single Cell Type RNA - Peritubular cells [nTPM]":"12.4","Single Cell Type RNA - Plasma cells [nTPM]":"22.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"31.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"51.1","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.2","Single Cell Type RNA - Spermatocytes [nTPM]":"86.9","Single Cell Type RNA - Spermatogonia [nTPM]":"32.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"19.2","Single Cell Type RNA - T-cells [nTPM]":"19.5","Single Cell Type RNA - Theca cells [nTPM]":"11.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.8","Single Cell Type RNA - Urothelial cells [nTPM]":"9.5"},{"Gene":"DHX30","Gene synonym":["DDX30","FLJ11214","KIAA0890"],"Ensembl":"ENSG00000132153","Gene description":"DExH-box helicase 30","Uniprot":["Q7L2E3"],"Chromosome":"3","Position":"47802909-47850195","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ribosome biogenesis"],"Molecular function":["Helicase","Hydrolase","RNA-binding"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034806"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA034806":"AB_10601364"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.37e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Tissue RNA - adipose tissue [nTPM]":"22.6","Tissue RNA - adrenal gland [nTPM]":"24.6","Tissue RNA - amygdala [nTPM]":"23.7","Tissue RNA - appendix [nTPM]":"17.1","Tissue RNA - basal ganglia [nTPM]":"23.3","Tissue RNA - bone marrow [nTPM]":"22.2","Tissue RNA - breast [nTPM]":"22.9","Tissue RNA - cerebellum [nTPM]":"21.4","Tissue RNA - cerebral cortex [nTPM]":"26.3","Tissue RNA - cervix [nTPM]":"26.4","Tissue RNA - choroid plexus [nTPM]":"24.8","Tissue RNA - colon [nTPM]":"26.8","Tissue RNA - duodenum [nTPM]":"16.2","Tissue RNA - endometrium 1 [nTPM]":"27.6","Tissue RNA - epididymis [nTPM]":"10.4","Tissue RNA - esophagus [nTPM]":"23.6","Tissue RNA - fallopian tube [nTPM]":"24.8","Tissue RNA - gallbladder [nTPM]":"14.9","Tissue RNA - heart muscle [nTPM]":"28.8","Tissue RNA - hippocampal formation [nTPM]":"23.5","Tissue RNA - hypothalamus [nTPM]":"22.4","Tissue RNA - kidney [nTPM]":"26.8","Tissue RNA - liver [nTPM]":"25.2","Tissue RNA - lung [nTPM]":"21.3","Tissue RNA - lymph node [nTPM]":"20.1","Tissue RNA - medulla oblongata [nTPM]":"24.0","Tissue RNA - midbrain [nTPM]":"23.5","Tissue RNA - ovary [nTPM]":"27.9","Tissue RNA - pancreas [nTPM]":"24.1","Tissue RNA - parathyroid gland [nTPM]":"28.9","Tissue RNA - pituitary gland [nTPM]":"32.1","Tissue RNA - placenta [nTPM]":"17.5","Tissue RNA - pons [nTPM]":"24.6","Tissue RNA - prostate [nTPM]":"26.6","Tissue RNA - rectum [nTPM]":"10.9","Tissue RNA - retina [nTPM]":"12.7","Tissue RNA - salivary gland [nTPM]":"21.6","Tissue RNA - seminal vesicle [nTPM]":"18.2","Tissue RNA - skeletal muscle [nTPM]":"37.1","Tissue RNA - skin 1 [nTPM]":"27.6","Tissue RNA - small intestine [nTPM]":"22.3","Tissue RNA - smooth muscle [nTPM]":"15.9","Tissue RNA - spinal cord [nTPM]":"20.3","Tissue RNA - spleen [nTPM]":"27.3","Tissue RNA - stomach 1 [nTPM]":"25.2","Tissue RNA - testis [nTPM]":"54.2","Tissue RNA - thalamus [nTPM]":"23.8","Tissue RNA - thymus [nTPM]":"23.3","Tissue RNA - thyroid gland [nTPM]":"24.8","Tissue RNA - tongue [nTPM]":"21.0","Tissue RNA - tonsil [nTPM]":"14.3","Tissue RNA - urinary bladder [nTPM]":"25.2","Tissue RNA - vagina [nTPM]":"22.8","Tissue RNA - white matter [nTPM]":"24.2","Cell RNA - A-431 [nTPM]":"21.9","Cell RNA - A549 [nTPM]":"52.3","Cell RNA - AF22 [nTPM]":"54.5","Cell RNA - AN3-CA [nTPM]":"56.2","Cell RNA - ASC diff [nTPM]":"24.6","Cell RNA - ASC TERT1 [nTPM]":"20.2","Cell RNA - BEWO [nTPM]":"35.3","Cell RNA - BJ [nTPM]":"39.0","Cell RNA - BJ hTERT+ [nTPM]":"33.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"65.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"46.5","Cell RNA - CACO-2 [nTPM]":"56.9","Cell RNA - CAPAN-2 [nTPM]":"42.6","Cell RNA - Daudi [nTPM]":"66.4","Cell RNA - EFO-21 [nTPM]":"32.0","Cell RNA - fHDF\/TERT166 [nTPM]":"37.0","Cell RNA - GAMG [nTPM]":"51.2","Cell RNA - HaCaT [nTPM]":"30.3","Cell RNA - HAP1 [nTPM]":"73.7","Cell RNA - HBEC3-KT [nTPM]":"52.1","Cell RNA - HBF TERT88 [nTPM]":"23.1","Cell RNA - HDLM-2 [nTPM]":"49.6","Cell RNA - HEK 293 [nTPM]":"86.1","Cell RNA - HEL [nTPM]":"59.6","Cell RNA - HeLa [nTPM]":"76.0","Cell RNA - Hep G2 [nTPM]":"58.6","Cell RNA - HHSteC [nTPM]":"40.7","Cell RNA - HL-60 [nTPM]":"56.0","Cell RNA - HMC-1 [nTPM]":"58.3","Cell RNA - HSkMC [nTPM]":"33.0","Cell RNA - hTCEpi [nTPM]":"33.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"68.1","Cell RNA - hTERT-HME1 [nTPM]":"49.7","Cell RNA - hTERT-RPE1 [nTPM]":"28.4","Cell RNA - HUVEC TERT2 [nTPM]":"44.0","Cell RNA - JURKAT [nTPM]":"57.5","Cell RNA - K-562 [nTPM]":"82.0","Cell RNA - Karpas-707 [nTPM]":"40.6","Cell RNA - LHCN-M2 [nTPM]":"31.8","Cell RNA - MCF7 [nTPM]":"57.1","Cell RNA - MOLT-4 [nTPM]":"82.2","Cell RNA - NB-4 [nTPM]":"59.3","Cell RNA - NTERA-2 [nTPM]":"60.7","Cell RNA - OE19 [nTPM]":"30.2","Cell RNA - PC-3 [nTPM]":"84.0","Cell RNA - REH [nTPM]":"44.6","Cell RNA - RH-30 [nTPM]":"30.6","Cell RNA - RPMI-8226 [nTPM]":"62.2","Cell RNA - RPTEC TERT1 [nTPM]":"32.0","Cell RNA - RT4 [nTPM]":"53.6","Cell RNA - SCLC-21H [nTPM]":"41.6","Cell RNA - SH-SY5Y [nTPM]":"61.6","Cell RNA - SiHa [nTPM]":"39.6","Cell RNA - SK-BR-3 [nTPM]":"54.1","Cell RNA - SK-MEL-30 [nTPM]":"31.1","Cell RNA - SuSa [nTPM]":"25.0","Cell RNA - T-47d [nTPM]":"38.5","Cell RNA - THP-1 [nTPM]":"58.8","Cell RNA - TIME [nTPM]":"32.2","Cell RNA - U-138 MG [nTPM]":"40.6","Cell RNA - U-2 OS [nTPM]":"51.0","Cell RNA - U-2197 [nTPM]":"46.7","Cell RNA - U-251 MG [nTPM]":"73.9","Cell RNA - U-266\/70 [nTPM]":"56.2","Cell RNA - U-266\/84 [nTPM]":"75.3","Cell RNA - U-698 [nTPM]":"61.8","Cell RNA - U-87 MG [nTPM]":"42.8","Cell RNA - U-937 [nTPM]":"48.3","Cell RNA - WM-115 [nTPM]":"49.9","Blood RNA - basophil [nTPM]":"14.1","Blood RNA - classical monocyte [nTPM]":"10.7","Blood RNA - eosinophil [nTPM]":"7.8","Blood RNA - gdT-cell [nTPM]":"16.2","Blood RNA - intermediate monocyte [nTPM]":"10.6","Blood RNA - MAIT T-cell [nTPM]":"12.4","Blood RNA - memory B-cell [nTPM]":"10.4","Blood RNA - memory CD4 T-cell [nTPM]":"12.4","Blood RNA - memory CD8 T-cell [nTPM]":"16.3","Blood RNA - myeloid DC [nTPM]":"13.9","Blood RNA - naive B-cell [nTPM]":"8.7","Blood RNA - naive CD4 T-cell [nTPM]":"11.7","Blood RNA - naive CD8 T-cell [nTPM]":"12.7","Blood RNA - neutrophil [nTPM]":"1.6","Blood RNA - NK-cell [nTPM]":"9.6","Blood RNA - non-classical monocyte [nTPM]":"11.6","Blood RNA - plasmacytoid DC [nTPM]":"7.9","Blood RNA - T-reg [nTPM]":"15.3","Blood RNA - total PBMC [nTPM]":"14.7","Brain RNA - amygdala [nTPM]":"23.7","Brain RNA - basal ganglia [nTPM]":"23.3","Brain RNA - cerebellum [nTPM]":"21.4","Brain RNA - cerebral cortex [nTPM]":"26.3","Brain RNA - hippocampal formation [nTPM]":"23.5","Brain RNA - hypothalamus [nTPM]":"22.4","Brain RNA - medulla oblongata [nTPM]":"24.0","Brain RNA - midbrain [nTPM]":"23.5","Brain RNA - pons [nTPM]":"24.6","Brain RNA - spinal cord [nTPM]":"20.3","Brain RNA - thalamus [nTPM]":"23.8","Brain RNA - white matter [nTPM]":"24.2","Single Cell Type RNA - Adipocytes [nTPM]":"31.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"46.7","Single Cell Type RNA - Astrocytes [nTPM]":"30.7","Single Cell Type RNA - B-cells [nTPM]":"34.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"25.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"38.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"39.3","Single Cell Type RNA - Bipolar cells [nTPM]":"49.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"34.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"35.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"38.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"34.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"51.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"43.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"41.7","Single Cell Type RNA - dendritic cells [nTPM]":"33.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"37.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"66.5","Single Cell Type RNA - Ductal cells [nTPM]":"37.8","Single Cell Type RNA - Early spermatids [nTPM]":"129.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"59.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"31.7","Single Cell Type RNA - Endothelial cells [nTPM]":"32.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"40.1","Single Cell Type RNA - Erythroid cells [nTPM]":"38.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"32.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"36.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"22.8","Single Cell Type RNA - Fibroblasts [nTPM]":"26.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"42.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"33.2","Single Cell Type RNA - granulocytes [nTPM]":"23.5","Single Cell Type RNA - Granulosa cells [nTPM]":"40.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"27.5","Single Cell Type RNA - Hepatocytes [nTPM]":"50.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"35.9","Single Cell Type RNA - Horizontal cells [nTPM]":"58.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"36.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"25.8","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"29.6","Single Cell Type RNA - Langerhans cells [nTPM]":"17.6","Single Cell Type RNA - Late spermatids [nTPM]":"123.8","Single Cell Type RNA - Leydig cells [nTPM]":"24.8","Single Cell Type RNA - Macrophages [nTPM]":"24.4","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"32.5","Single Cell Type RNA - Muller glia cells [nTPM]":"46.3","Single Cell Type RNA - NK-cells [nTPM]":"28.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"22.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"28.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"46.0","Single Cell Type RNA - Paneth cells [nTPM]":"41.0","Single Cell Type RNA - Peritubular cells [nTPM]":"30.1","Single Cell Type RNA - Plasma cells [nTPM]":"39.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"28.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"40.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"83.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"49.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"52.8","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"28.6","Single Cell Type RNA - Spermatocytes [nTPM]":"145.4","Single Cell Type RNA - Spermatogonia [nTPM]":"50.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"33.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"19.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"29.6","Single Cell Type RNA - T-cells [nTPM]":"29.7","Single Cell Type RNA - Theca cells [nTPM]":"36.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"38.5","Single Cell Type RNA - Urothelial cells [nTPM]":"26.3"},{"Gene":"DHX37","Gene synonym":["DDX37","Dhr1","KIAA1517","MGC2695","MGC4322"],"Ensembl":"ENSG00000150990","Gene description":"DEAH-box helicase 37","Uniprot":["Q8IY37"],"Chromosome":"12","Position":"124946825-124989131","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Helicase","Hydrolase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047607"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA047607":"AB_2680101"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.54e-10"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Tissue RNA - adipose tissue [nTPM]":"4.3","Tissue RNA - adrenal gland [nTPM]":"3.2","Tissue RNA - amygdala [nTPM]":"2.9","Tissue RNA - appendix [nTPM]":"6.8","Tissue RNA - basal ganglia [nTPM]":"3.4","Tissue RNA - bone marrow [nTPM]":"8.8","Tissue RNA - breast [nTPM]":"3.6","Tissue RNA - cerebellum [nTPM]":"3.0","Tissue RNA - cerebral cortex [nTPM]":"3.6","Tissue RNA - cervix [nTPM]":"3.5","Tissue RNA - choroid plexus [nTPM]":"1.4","Tissue RNA - colon [nTPM]":"3.4","Tissue RNA - duodenum [nTPM]":"4.4","Tissue RNA - endometrium 1 [nTPM]":"3.8","Tissue RNA - epididymis [nTPM]":"1.3","Tissue RNA - esophagus [nTPM]":"4.7","Tissue RNA - fallopian tube [nTPM]":"3.4","Tissue RNA - gallbladder [nTPM]":"2.8","Tissue RNA - heart muscle [nTPM]":"3.6","Tissue RNA - hippocampal formation [nTPM]":"2.9","Tissue RNA - hypothalamus [nTPM]":"2.5","Tissue RNA - kidney [nTPM]":"3.3","Tissue RNA - liver [nTPM]":"3.0","Tissue RNA - lung [nTPM]":"2.8","Tissue RNA - lymph node [nTPM]":"7.4","Tissue RNA - medulla oblongata [nTPM]":"4.1","Tissue RNA - midbrain [nTPM]":"3.6","Tissue RNA - ovary [nTPM]":"4.5","Tissue RNA - pancreas [nTPM]":"6.6","Tissue RNA - parathyroid gland [nTPM]":"2.6","Tissue RNA - pituitary gland [nTPM]":"1.6","Tissue RNA - placenta [nTPM]":"2.9","Tissue RNA - pons [nTPM]":"3.4","Tissue RNA - prostate [nTPM]":"3.3","Tissue RNA - rectum [nTPM]":"1.6","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"4.3","Tissue RNA - seminal vesicle [nTPM]":"2.6","Tissue RNA - skeletal muscle [nTPM]":"10.8","Tissue RNA - skin 1 [nTPM]":"4.0","Tissue RNA - small intestine [nTPM]":"3.8","Tissue RNA - smooth muscle [nTPM]":"2.5","Tissue RNA - spinal cord [nTPM]":"3.0","Tissue RNA - spleen [nTPM]":"5.2","Tissue RNA - stomach 1 [nTPM]":"3.9","Tissue RNA - testis [nTPM]":"2.6","Tissue RNA - thalamus [nTPM]":"3.2","Tissue RNA - thymus [nTPM]":"4.6","Tissue RNA - thyroid gland [nTPM]":"3.2","Tissue RNA - tongue [nTPM]":"4.9","Tissue RNA - tonsil [nTPM]":"3.9","Tissue RNA - urinary bladder [nTPM]":"5.0","Tissue RNA - vagina [nTPM]":"3.6","Tissue RNA - white matter [nTPM]":"4.3","Cell RNA - A-431 [nTPM]":"17.3","Cell RNA - A549 [nTPM]":"45.5","Cell RNA - AF22 [nTPM]":"5.2","Cell RNA - AN3-CA [nTPM]":"21.9","Cell RNA - ASC diff [nTPM]":"6.7","Cell RNA - ASC TERT1 [nTPM]":"6.6","Cell RNA - BEWO [nTPM]":"27.4","Cell RNA - BJ [nTPM]":"13.8","Cell RNA - BJ hTERT+ [nTPM]":"7.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.6","Cell RNA - CACO-2 [nTPM]":"44.7","Cell RNA - CAPAN-2 [nTPM]":"9.4","Cell RNA - Daudi [nTPM]":"37.5","Cell RNA - EFO-21 [nTPM]":"24.6","Cell RNA - fHDF\/TERT166 [nTPM]":"11.4","Cell RNA - GAMG [nTPM]":"19.7","Cell RNA - HaCaT [nTPM]":"21.9","Cell RNA - HAP1 [nTPM]":"19.8","Cell RNA - HBEC3-KT [nTPM]":"15.6","Cell RNA - HBF TERT88 [nTPM]":"4.5","Cell RNA - HDLM-2 [nTPM]":"32.7","Cell RNA - HEK 293 [nTPM]":"38.2","Cell RNA - HEL [nTPM]":"23.0","Cell RNA - HeLa [nTPM]":"13.8","Cell RNA - Hep G2 [nTPM]":"23.7","Cell RNA - HHSteC [nTPM]":"13.4","Cell RNA - HL-60 [nTPM]":"27.7","Cell RNA - HMC-1 [nTPM]":"30.5","Cell RNA - HSkMC [nTPM]":"8.8","Cell RNA - hTCEpi [nTPM]":"10.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"24.3","Cell RNA - hTERT-HME1 [nTPM]":"4.0","Cell RNA - hTERT-RPE1 [nTPM]":"7.2","Cell RNA - HUVEC TERT2 [nTPM]":"10.0","Cell RNA - JURKAT [nTPM]":"17.4","Cell RNA - K-562 [nTPM]":"44.4","Cell RNA - Karpas-707 [nTPM]":"7.5","Cell RNA - LHCN-M2 [nTPM]":"7.5","Cell RNA - MCF7 [nTPM]":"23.9","Cell RNA - MOLT-4 [nTPM]":"29.5","Cell RNA - NB-4 [nTPM]":"28.5","Cell RNA - NTERA-2 [nTPM]":"39.2","Cell RNA - OE19 [nTPM]":"15.1","Cell RNA - PC-3 [nTPM]":"36.4","Cell RNA - REH [nTPM]":"31.4","Cell RNA - RH-30 [nTPM]":"11.0","Cell RNA - RPMI-8226 [nTPM]":"21.5","Cell RNA - RPTEC TERT1 [nTPM]":"8.6","Cell RNA - RT4 [nTPM]":"22.6","Cell RNA - SCLC-21H [nTPM]":"17.6","Cell RNA - SH-SY5Y [nTPM]":"11.1","Cell RNA - SiHa [nTPM]":"14.0","Cell RNA - SK-BR-3 [nTPM]":"16.3","Cell RNA - SK-MEL-30 [nTPM]":"16.0","Cell RNA - SuSa [nTPM]":"5.1","Cell RNA - T-47d [nTPM]":"19.3","Cell RNA - THP-1 [nTPM]":"19.5","Cell RNA - TIME [nTPM]":"13.1","Cell RNA - U-138 MG [nTPM]":"16.1","Cell RNA - U-2 OS [nTPM]":"20.2","Cell RNA - U-2197 [nTPM]":"20.0","Cell RNA - U-251 MG [nTPM]":"27.6","Cell RNA - U-266\/70 [nTPM]":"31.6","Cell RNA - U-266\/84 [nTPM]":"33.2","Cell RNA - U-698 [nTPM]":"44.0","Cell RNA - U-87 MG [nTPM]":"15.1","Cell RNA - U-937 [nTPM]":"22.2","Cell RNA - WM-115 [nTPM]":"27.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.5","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"1.7","Blood RNA - MAIT T-cell [nTPM]":"1.4","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"1.6","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"1.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.9","Blood RNA - naive CD8 T-cell [nTPM]":"1.4","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.9","Blood RNA - non-classical monocyte [nTPM]":"0.8","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"2.9","Brain RNA - basal ganglia [nTPM]":"3.4","Brain RNA - cerebellum [nTPM]":"3.0","Brain RNA - cerebral cortex [nTPM]":"3.6","Brain RNA - hippocampal formation [nTPM]":"2.9","Brain RNA - hypothalamus [nTPM]":"2.5","Brain RNA - medulla oblongata [nTPM]":"4.1","Brain RNA - midbrain [nTPM]":"3.6","Brain RNA - pons [nTPM]":"3.4","Brain RNA - spinal cord [nTPM]":"3.0","Brain RNA - thalamus [nTPM]":"3.2","Brain RNA - white matter [nTPM]":"4.3","Single Cell Type RNA - Adipocytes [nTPM]":"5.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.2","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"10.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"3.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"4.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.1","Single Cell Type RNA - dendritic cells [nTPM]":"6.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.8","Single Cell Type RNA - Early spermatids [nTPM]":"1.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.6","Single Cell Type RNA - Endothelial cells [nTPM]":"5.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.0","Single Cell Type RNA - Fibroblasts [nTPM]":"4.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.8","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"9.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"6.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.4","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.1","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"7.2","Single Cell Type RNA - Langerhans cells [nTPM]":"2.5","Single Cell Type RNA - Late spermatids [nTPM]":"2.0","Single Cell Type RNA - Leydig cells [nTPM]":"5.3","Single Cell Type RNA - Macrophages [nTPM]":"4.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"6.6","Single Cell Type RNA - Muller glia cells [nTPM]":"2.2","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.0","Single Cell Type RNA - Paneth cells [nTPM]":"2.2","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"9.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.8","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"5.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.9","Single Cell Type RNA - T-cells [nTPM]":"7.7","Single Cell Type RNA - Theca cells [nTPM]":"5.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.3","Single Cell Type RNA - Urothelial cells [nTPM]":"4.0"},{"Gene":"DHX38","Gene synonym":["DDX38","hPrp16","KIAA0224","PRP16","PRPF16"],"Ensembl":"ENSG00000140829","Gene description":"DEAH-box helicase 38","Uniprot":["Q92620"],"Chromosome":"16","Position":"72093613-72112912","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":["Helicase","Hydrolase"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041347","HPA041604"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA041347":"AB_10796571","HPA041604":"AB_2677577"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.50e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Tissue RNA - adipose tissue [nTPM]":"25.8","Tissue RNA - adrenal gland [nTPM]":"18.7","Tissue RNA - amygdala [nTPM]":"22.4","Tissue RNA - appendix [nTPM]":"22.8","Tissue RNA - basal ganglia [nTPM]":"24.4","Tissue RNA - bone marrow [nTPM]":"39.7","Tissue RNA - breast [nTPM]":"23.8","Tissue RNA - cerebellum [nTPM]":"22.2","Tissue RNA - cerebral cortex [nTPM]":"24.7","Tissue RNA - cervix [nTPM]":"25.1","Tissue RNA - choroid plexus [nTPM]":"25.9","Tissue RNA - colon [nTPM]":"24.8","Tissue RNA - duodenum [nTPM]":"19.6","Tissue RNA - endometrium 1 [nTPM]":"25.5","Tissue RNA - epididymis [nTPM]":"10.7","Tissue RNA - esophagus [nTPM]":"24.2","Tissue RNA - fallopian tube [nTPM]":"23.8","Tissue RNA - gallbladder [nTPM]":"15.0","Tissue RNA - heart muscle [nTPM]":"27.0","Tissue RNA - hippocampal formation [nTPM]":"21.5","Tissue RNA - hypothalamus [nTPM]":"21.6","Tissue RNA - kidney [nTPM]":"19.6","Tissue RNA - liver [nTPM]":"24.0","Tissue RNA - lung [nTPM]":"23.9","Tissue RNA - lymph node [nTPM]":"27.8","Tissue RNA - medulla oblongata [nTPM]":"23.2","Tissue RNA - midbrain [nTPM]":"23.2","Tissue RNA - ovary [nTPM]":"30.6","Tissue RNA - pancreas [nTPM]":"20.2","Tissue RNA - parathyroid gland [nTPM]":"22.9","Tissue RNA - pituitary gland [nTPM]":"19.3","Tissue RNA - placenta [nTPM]":"18.6","Tissue RNA - pons [nTPM]":"22.5","Tissue RNA - prostate [nTPM]":"20.9","Tissue RNA - rectum [nTPM]":"16.1","Tissue RNA - retina [nTPM]":"13.2","Tissue RNA - salivary gland [nTPM]":"21.1","Tissue RNA - seminal vesicle [nTPM]":"14.4","Tissue RNA - skeletal muscle [nTPM]":"39.9","Tissue RNA - skin 1 [nTPM]":"27.6","Tissue RNA - small intestine [nTPM]":"27.3","Tissue RNA - smooth muscle [nTPM]":"17.6","Tissue RNA - spinal cord [nTPM]":"22.2","Tissue RNA - spleen [nTPM]":"30.4","Tissue RNA - stomach 1 [nTPM]":"22.5","Tissue RNA - testis [nTPM]":"21.3","Tissue RNA - thalamus [nTPM]":"23.5","Tissue RNA - thymus [nTPM]":"24.2","Tissue RNA - thyroid gland [nTPM]":"22.8","Tissue RNA - tongue [nTPM]":"21.4","Tissue RNA - tonsil [nTPM]":"23.1","Tissue RNA - urinary bladder [nTPM]":"23.7","Tissue RNA - vagina [nTPM]":"22.9","Tissue RNA - white matter [nTPM]":"25.0","Cell RNA - A-431 [nTPM]":"38.5","Cell RNA - A549 [nTPM]":"55.0","Cell RNA - AF22 [nTPM]":"39.4","Cell RNA - AN3-CA [nTPM]":"21.9","Cell RNA - ASC diff [nTPM]":"33.4","Cell RNA - ASC TERT1 [nTPM]":"25.8","Cell RNA - BEWO [nTPM]":"51.1","Cell RNA - BJ [nTPM]":"33.6","Cell RNA - BJ hTERT+ [nTPM]":"32.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"49.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"37.8","Cell RNA - CACO-2 [nTPM]":"66.4","Cell RNA - CAPAN-2 [nTPM]":"37.5","Cell RNA - Daudi [nTPM]":"50.5","Cell RNA - EFO-21 [nTPM]":"29.2","Cell RNA - fHDF\/TERT166 [nTPM]":"50.9","Cell RNA - GAMG [nTPM]":"27.0","Cell RNA - HaCaT [nTPM]":"48.6","Cell RNA - HAP1 [nTPM]":"46.3","Cell RNA - HBEC3-KT [nTPM]":"45.8","Cell RNA - HBF TERT88 [nTPM]":"38.0","Cell RNA - HDLM-2 [nTPM]":"25.3","Cell RNA - HEK 293 [nTPM]":"50.0","Cell RNA - HEL [nTPM]":"38.7","Cell RNA - HeLa [nTPM]":"48.9","Cell RNA - Hep G2 [nTPM]":"92.5","Cell RNA - HHSteC [nTPM]":"30.8","Cell RNA - HL-60 [nTPM]":"46.9","Cell RNA - HMC-1 [nTPM]":"66.7","Cell RNA - HSkMC [nTPM]":"35.6","Cell RNA - hTCEpi [nTPM]":"41.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"66.1","Cell RNA - hTERT-HME1 [nTPM]":"47.4","Cell RNA - hTERT-RPE1 [nTPM]":"25.9","Cell RNA - HUVEC TERT2 [nTPM]":"42.9","Cell RNA - JURKAT [nTPM]":"35.7","Cell RNA - K-562 [nTPM]":"58.9","Cell RNA - Karpas-707 [nTPM]":"22.9","Cell RNA - LHCN-M2 [nTPM]":"30.6","Cell RNA - MCF7 [nTPM]":"112.8","Cell RNA - MOLT-4 [nTPM]":"43.9","Cell RNA - NB-4 [nTPM]":"53.1","Cell RNA - NTERA-2 [nTPM]":"49.7","Cell RNA - OE19 [nTPM]":"23.9","Cell RNA - PC-3 [nTPM]":"30.9","Cell RNA - REH [nTPM]":"55.8","Cell RNA - RH-30 [nTPM]":"27.1","Cell RNA - RPMI-8226 [nTPM]":"49.9","Cell RNA - RPTEC TERT1 [nTPM]":"24.0","Cell RNA - RT4 [nTPM]":"35.6","Cell RNA - SCLC-21H [nTPM]":"35.6","Cell RNA - SH-SY5Y [nTPM]":"38.9","Cell RNA - SiHa [nTPM]":"43.8","Cell RNA - SK-BR-3 [nTPM]":"20.3","Cell RNA - SK-MEL-30 [nTPM]":"24.5","Cell RNA - SuSa [nTPM]":"22.5","Cell RNA - T-47d [nTPM]":"36.8","Cell RNA - THP-1 [nTPM]":"38.4","Cell RNA - TIME [nTPM]":"49.4","Cell RNA - U-138 MG [nTPM]":"46.6","Cell RNA - U-2 OS [nTPM]":"40.8","Cell RNA - U-2197 [nTPM]":"34.8","Cell RNA - U-251 MG [nTPM]":"37.3","Cell RNA - U-266\/70 [nTPM]":"56.2","Cell RNA - U-266\/84 [nTPM]":"47.6","Cell RNA - U-698 [nTPM]":"96.7","Cell RNA - U-87 MG [nTPM]":"43.9","Cell RNA - U-937 [nTPM]":"32.1","Cell RNA - WM-115 [nTPM]":"37.5","Blood RNA - basophil [nTPM]":"7.1","Blood RNA - classical monocyte [nTPM]":"6.2","Blood RNA - eosinophil [nTPM]":"7.1","Blood RNA - gdT-cell [nTPM]":"11.3","Blood RNA - intermediate monocyte [nTPM]":"8.3","Blood RNA - MAIT T-cell [nTPM]":"9.8","Blood RNA - memory B-cell [nTPM]":"8.1","Blood RNA - memory CD4 T-cell [nTPM]":"6.8","Blood RNA - memory CD8 T-cell [nTPM]":"8.2","Blood RNA - myeloid DC [nTPM]":"6.2","Blood RNA - naive B-cell [nTPM]":"6.0","Blood RNA - naive CD4 T-cell [nTPM]":"7.4","Blood RNA - naive CD8 T-cell [nTPM]":"7.9","Blood RNA - neutrophil [nTPM]":"6.4","Blood RNA - NK-cell [nTPM]":"8.8","Blood RNA - non-classical monocyte [nTPM]":"5.1","Blood RNA - plasmacytoid DC [nTPM]":"5.5","Blood RNA - T-reg [nTPM]":"8.6","Blood RNA - total PBMC [nTPM]":"5.5","Brain RNA - amygdala [nTPM]":"22.4","Brain RNA - basal ganglia [nTPM]":"24.4","Brain RNA - cerebellum [nTPM]":"22.2","Brain RNA - cerebral cortex [nTPM]":"24.7","Brain RNA - hippocampal formation [nTPM]":"21.5","Brain RNA - hypothalamus [nTPM]":"21.6","Brain RNA - medulla oblongata [nTPM]":"23.2","Brain RNA - midbrain [nTPM]":"23.2","Brain RNA - pons [nTPM]":"22.5","Brain RNA - spinal cord [nTPM]":"22.2","Brain RNA - thalamus [nTPM]":"23.5","Brain RNA - white matter [nTPM]":"25.0","Single Cell Type RNA - Adipocytes [nTPM]":"22.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"34.3","Single Cell Type RNA - Astrocytes [nTPM]":"13.7","Single Cell Type RNA - B-cells [nTPM]":"24.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"20.5","Single Cell Type RNA - Bipolar cells [nTPM]":"30.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"22.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.0","Single Cell Type RNA - dendritic cells [nTPM]":"33.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"28.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"14.5","Single Cell Type RNA - Early spermatids [nTPM]":"9.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.0","Single Cell Type RNA - Endothelial cells [nTPM]":"22.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"30.5","Single Cell Type RNA - Erythroid cells [nTPM]":"16.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"20.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.3","Single Cell Type RNA - Fibroblasts [nTPM]":"17.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"28.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"23.6","Single Cell Type RNA - granulocytes [nTPM]":"43.0","Single Cell Type RNA - Granulosa cells [nTPM]":"24.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.0","Single Cell Type RNA - Hepatocytes [nTPM]":"13.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.9","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.8","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"15.2","Single Cell Type RNA - Langerhans cells [nTPM]":"13.9","Single Cell Type RNA - Late spermatids [nTPM]":"11.0","Single Cell Type RNA - Leydig cells [nTPM]":"28.9","Single Cell Type RNA - Macrophages [nTPM]":"20.3","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"16.9","Single Cell Type RNA - Muller glia cells [nTPM]":"17.9","Single Cell Type RNA - NK-cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"23.7","Single Cell Type RNA - Paneth cells [nTPM]":"17.1","Single Cell Type RNA - Peritubular cells [nTPM]":"25.2","Single Cell Type RNA - Plasma cells [nTPM]":"22.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"21.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"35.3","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"25.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.1","Single Cell Type RNA - Spermatocytes [nTPM]":"25.5","Single Cell Type RNA - Spermatogonia [nTPM]":"17.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.4","Single Cell Type RNA - T-cells [nTPM]":"28.2","Single Cell Type RNA - Theca cells [nTPM]":"20.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.4","Single Cell Type RNA - Urothelial cells [nTPM]":"12.6"},{"Gene":"DICER1","Gene synonym":["Dicer","HERNA","K12H4.8-LIKE","KIAA0928","MNG1"],"Ensembl":"ENSG00000100697","Gene description":"Dicer 1, ribonuclease III","Uniprot":["Q9UPY3"],"Chromosome":"14","Position":"95086228-95158010","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Host-virus interaction","RNA-mediated gene silencing"],"Molecular function":["Endonuclease","Helicase","Hydrolase","Nuclease","RNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"418.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000694","CAB068185"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB068185":"AB_2665650","HPA000694":"AB_1078661"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.52e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.6","Tissue RNA - adrenal gland [nTPM]":"7.9","Tissue RNA - amygdala [nTPM]":"6.7","Tissue RNA - appendix [nTPM]":"14.0","Tissue RNA - basal ganglia [nTPM]":"22.5","Tissue RNA - bone marrow [nTPM]":"10.8","Tissue RNA - breast [nTPM]":"15.1","Tissue RNA - cerebellum [nTPM]":"12.3","Tissue RNA - cerebral cortex [nTPM]":"11.4","Tissue RNA - cervix [nTPM]":"13.3","Tissue RNA - choroid plexus [nTPM]":"7.4","Tissue RNA - colon [nTPM]":"13.0","Tissue RNA - duodenum [nTPM]":"7.5","Tissue RNA - endometrium 1 [nTPM]":"12.7","Tissue RNA - epididymis [nTPM]":"8.3","Tissue RNA - esophagus [nTPM]":"15.0","Tissue RNA - fallopian tube [nTPM]":"12.4","Tissue RNA - gallbladder [nTPM]":"8.7","Tissue RNA - heart muscle [nTPM]":"9.9","Tissue RNA - hippocampal formation [nTPM]":"7.2","Tissue RNA - hypothalamus [nTPM]":"14.0","Tissue RNA - kidney [nTPM]":"10.7","Tissue RNA - liver [nTPM]":"12.8","Tissue RNA - lung [nTPM]":"14.9","Tissue RNA - lymph node [nTPM]":"11.0","Tissue RNA - medulla oblongata [nTPM]":"19.1","Tissue RNA - midbrain [nTPM]":"16.0","Tissue RNA - ovary [nTPM]":"14.3","Tissue RNA - pancreas [nTPM]":"12.6","Tissue RNA - parathyroid gland [nTPM]":"11.5","Tissue RNA - pituitary gland [nTPM]":"10.6","Tissue RNA - placenta [nTPM]":"18.7","Tissue RNA - pons [nTPM]":"18.5","Tissue RNA - prostate [nTPM]":"12.5","Tissue RNA - rectum [nTPM]":"10.9","Tissue RNA - retina [nTPM]":"19.3","Tissue RNA - salivary gland [nTPM]":"12.4","Tissue RNA - seminal vesicle [nTPM]":"10.1","Tissue RNA - skeletal muscle [nTPM]":"19.2","Tissue RNA - skin 1 [nTPM]":"13.0","Tissue RNA - small intestine [nTPM]":"11.6","Tissue RNA - smooth muscle [nTPM]":"11.5","Tissue RNA - spinal cord [nTPM]":"11.6","Tissue RNA - spleen [nTPM]":"12.1","Tissue RNA - stomach 1 [nTPM]":"10.1","Tissue RNA - testis [nTPM]":"13.2","Tissue RNA - thalamus [nTPM]":"20.3","Tissue RNA - thymus [nTPM]":"8.5","Tissue RNA - thyroid gland [nTPM]":"14.7","Tissue RNA - tongue [nTPM]":"16.2","Tissue RNA - tonsil [nTPM]":"12.0","Tissue RNA - urinary bladder [nTPM]":"12.7","Tissue RNA - vagina [nTPM]":"14.5","Tissue RNA - white matter [nTPM]":"39.4","Cell RNA - A-431 [nTPM]":"18.6","Cell RNA - A549 [nTPM]":"19.4","Cell RNA - AF22 [nTPM]":"40.7","Cell RNA - AN3-CA [nTPM]":"12.0","Cell RNA - ASC diff [nTPM]":"7.2","Cell RNA - ASC TERT1 [nTPM]":"14.5","Cell RNA - BEWO [nTPM]":"26.4","Cell RNA - BJ [nTPM]":"15.5","Cell RNA - BJ hTERT+ [nTPM]":"10.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.1","Cell RNA - CACO-2 [nTPM]":"25.4","Cell RNA - CAPAN-2 [nTPM]":"12.5","Cell RNA - Daudi [nTPM]":"20.9","Cell RNA - EFO-21 [nTPM]":"16.1","Cell RNA - fHDF\/TERT166 [nTPM]":"16.0","Cell RNA - GAMG [nTPM]":"10.4","Cell RNA - HaCaT [nTPM]":"21.2","Cell RNA - HAP1 [nTPM]":"31.6","Cell RNA - HBEC3-KT [nTPM]":"13.9","Cell RNA - HBF TERT88 [nTPM]":"20.5","Cell RNA - HDLM-2 [nTPM]":"35.9","Cell RNA - HEK 293 [nTPM]":"14.6","Cell RNA - HEL [nTPM]":"36.5","Cell RNA - HeLa [nTPM]":"10.1","Cell RNA - Hep G2 [nTPM]":"16.0","Cell RNA - HHSteC [nTPM]":"6.7","Cell RNA - HL-60 [nTPM]":"22.6","Cell RNA - HMC-1 [nTPM]":"18.0","Cell RNA - HSkMC [nTPM]":"12.2","Cell RNA - hTCEpi [nTPM]":"10.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.3","Cell RNA - hTERT-HME1 [nTPM]":"20.8","Cell RNA - hTERT-RPE1 [nTPM]":"8.0","Cell RNA - HUVEC TERT2 [nTPM]":"16.1","Cell RNA - JURKAT [nTPM]":"15.7","Cell RNA - K-562 [nTPM]":"15.7","Cell RNA - Karpas-707 [nTPM]":"16.6","Cell RNA - LHCN-M2 [nTPM]":"16.9","Cell RNA - MCF7 [nTPM]":"21.8","Cell RNA - MOLT-4 [nTPM]":"24.1","Cell RNA - NB-4 [nTPM]":"6.8","Cell RNA - NTERA-2 [nTPM]":"9.3","Cell RNA - OE19 [nTPM]":"11.0","Cell RNA - PC-3 [nTPM]":"10.2","Cell RNA - REH [nTPM]":"16.0","Cell RNA - RH-30 [nTPM]":"31.9","Cell RNA - RPMI-8226 [nTPM]":"12.2","Cell RNA - RPTEC TERT1 [nTPM]":"8.2","Cell RNA - RT4 [nTPM]":"30.9","Cell RNA - SCLC-21H [nTPM]":"31.9","Cell RNA - SH-SY5Y [nTPM]":"16.4","Cell RNA - SiHa [nTPM]":"16.2","Cell RNA - SK-BR-3 [nTPM]":"13.4","Cell RNA - SK-MEL-30 [nTPM]":"15.2","Cell RNA - SuSa [nTPM]":"19.2","Cell RNA - T-47d [nTPM]":"18.0","Cell RNA - THP-1 [nTPM]":"12.4","Cell RNA - TIME [nTPM]":"16.4","Cell RNA - U-138 MG [nTPM]":"8.1","Cell RNA - U-2 OS [nTPM]":"14.4","Cell RNA - U-2197 [nTPM]":"14.0","Cell RNA - U-251 MG [nTPM]":"16.9","Cell RNA - U-266\/70 [nTPM]":"18.9","Cell RNA - U-266\/84 [nTPM]":"31.7","Cell RNA - U-698 [nTPM]":"31.4","Cell RNA - U-87 MG [nTPM]":"8.0","Cell RNA - U-937 [nTPM]":"14.5","Cell RNA - WM-115 [nTPM]":"13.1","Blood RNA - basophil [nTPM]":"1.4","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"0.8","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"1.4","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.8","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"3.9","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"3.2","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"6.7","Brain RNA - basal ganglia [nTPM]":"22.5","Brain RNA - cerebellum [nTPM]":"12.3","Brain RNA - cerebral cortex [nTPM]":"11.4","Brain RNA - hippocampal formation [nTPM]":"7.2","Brain RNA - hypothalamus [nTPM]":"14.0","Brain RNA - medulla oblongata [nTPM]":"19.1","Brain RNA - midbrain [nTPM]":"16.0","Brain RNA - pons [nTPM]":"18.5","Brain RNA - spinal cord [nTPM]":"11.6","Brain RNA - thalamus [nTPM]":"20.3","Brain RNA - white matter [nTPM]":"39.4","Single Cell Type RNA - Adipocytes [nTPM]":"69.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"54.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"53.7","Single Cell Type RNA - Astrocytes [nTPM]":"88.8","Single Cell Type RNA - B-cells [nTPM]":"45.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"27.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"49.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"40.5","Single Cell Type RNA - Bipolar cells [nTPM]":"98.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"50.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"29.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"36.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"41.5","Single Cell Type RNA - Club cells [nTPM]":"47.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"46.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"56.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"46.6","Single Cell Type RNA - dendritic cells [nTPM]":"36.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"33.4","Single Cell Type RNA - Early spermatids [nTPM]":"23.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"37.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"54.2","Single Cell Type RNA - Endothelial cells [nTPM]":"52.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"46.1","Single Cell Type RNA - Erythroid cells [nTPM]":"33.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"99.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"22.8","Single Cell Type RNA - Fibroblasts [nTPM]":"45.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"33.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"50.1","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"35.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"42.1","Single Cell Type RNA - Hepatocytes [nTPM]":"60.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"48.8","Single Cell Type RNA - Horizontal cells [nTPM]":"107.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"112.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"29.7","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"104.2","Single Cell Type RNA - Langerhans cells [nTPM]":"24.8","Single Cell Type RNA - Late spermatids [nTPM]":"15.5","Single Cell Type RNA - Leydig cells [nTPM]":"54.3","Single Cell Type RNA - Macrophages [nTPM]":"82.3","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"81.5","Single Cell Type RNA - monocytes [nTPM]":"84.6","Single Cell Type RNA - Muller glia cells [nTPM]":"33.5","Single Cell Type RNA - NK-cells [nTPM]":"33.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"109.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"418.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"33.2","Single Cell Type RNA - Paneth cells [nTPM]":"28.0","Single Cell Type RNA - Peritubular cells [nTPM]":"52.6","Single Cell Type RNA - Plasma cells [nTPM]":"39.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"62.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"27.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"25.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"38.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"73.8","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"64.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"41.9","Single Cell Type RNA - Spermatocytes [nTPM]":"45.5","Single Cell Type RNA - Spermatogonia [nTPM]":"56.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"63.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"25.7","Single Cell Type RNA - T-cells [nTPM]":"31.7","Single Cell Type RNA - Theca cells [nTPM]":"35.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"33.9","Single Cell Type RNA - Urothelial cells [nTPM]":"62.1"},{"Gene":"DLAT","Gene synonym":["DLTA","E2","PDC-E2"],"Ensembl":"ENSG00000150768","Gene description":"Dihydrolipoamide S-acetyltransferase","Uniprot":["P10515"],"Chromosome":"11","Position":"112025408-112064404","Protein class":["Citric acid cycle related proteins","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism","Glucose metabolism","Tricarboxylic acid cycle"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"tongue":"89.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"100.5","Distal tubular cells":"74.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003782","HPA040786","HPA062766"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"44000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB003782":null,"HPA040786":"AB_2677136","HPA062766":"AB_2684864"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.19e-6"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.49e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.95e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-2"},"Tissue RNA - adipose tissue [nTPM]":"24.7","Tissue RNA - adrenal gland [nTPM]":"16.5","Tissue RNA - amygdala [nTPM]":"7.7","Tissue RNA - appendix [nTPM]":"13.3","Tissue RNA - basal ganglia [nTPM]":"8.3","Tissue RNA - bone marrow [nTPM]":"7.9","Tissue RNA - breast [nTPM]":"14.5","Tissue RNA - cerebellum [nTPM]":"9.5","Tissue RNA - cerebral cortex [nTPM]":"9.3","Tissue RNA - cervix [nTPM]":"11.0","Tissue RNA - choroid plexus [nTPM]":"10.4","Tissue RNA - colon [nTPM]":"24.7","Tissue RNA - duodenum [nTPM]":"18.3","Tissue RNA - endometrium 1 [nTPM]":"10.0","Tissue RNA - epididymis [nTPM]":"13.4","Tissue RNA - esophagus [nTPM]":"19.5","Tissue RNA - fallopian tube [nTPM]":"13.0","Tissue RNA - gallbladder [nTPM]":"8.5","Tissue RNA - heart muscle [nTPM]":"69.4","Tissue RNA - hippocampal formation [nTPM]":"8.1","Tissue RNA - hypothalamus [nTPM]":"11.1","Tissue RNA - kidney [nTPM]":"33.8","Tissue RNA - liver [nTPM]":"15.5","Tissue RNA - lung [nTPM]":"11.7","Tissue RNA - lymph node [nTPM]":"16.1","Tissue RNA - medulla oblongata [nTPM]":"8.3","Tissue RNA - midbrain [nTPM]":"8.9","Tissue RNA - ovary [nTPM]":"9.5","Tissue RNA - pancreas [nTPM]":"6.8","Tissue RNA - parathyroid gland [nTPM]":"31.7","Tissue RNA - pituitary gland [nTPM]":"8.5","Tissue RNA - placenta [nTPM]":"13.1","Tissue RNA - pons [nTPM]":"9.7","Tissue RNA - prostate [nTPM]":"14.5","Tissue RNA - rectum [nTPM]":"26.0","Tissue RNA - retina [nTPM]":"10.8","Tissue RNA - salivary gland [nTPM]":"16.8","Tissue RNA - seminal vesicle [nTPM]":"14.8","Tissue RNA - skeletal muscle [nTPM]":"75.4","Tissue RNA - skin 1 [nTPM]":"10.3","Tissue RNA - small intestine [nTPM]":"16.5","Tissue RNA - smooth muscle [nTPM]":"13.4","Tissue RNA - spinal cord [nTPM]":"8.2","Tissue RNA - spleen [nTPM]":"9.9","Tissue RNA - stomach 1 [nTPM]":"14.3","Tissue RNA - testis [nTPM]":"9.9","Tissue RNA - thalamus [nTPM]":"9.4","Tissue RNA - thymus [nTPM]":"12.7","Tissue RNA - thyroid gland [nTPM]":"20.2","Tissue RNA - tongue [nTPM]":"89.4","Tissue RNA - tonsil [nTPM]":"18.2","Tissue RNA - urinary bladder [nTPM]":"14.2","Tissue RNA - vagina [nTPM]":"8.1","Tissue RNA - white matter [nTPM]":"8.0","Cell RNA - A-431 [nTPM]":"18.7","Cell RNA - A549 [nTPM]":"16.4","Cell RNA - AF22 [nTPM]":"28.2","Cell RNA - AN3-CA [nTPM]":"34.4","Cell RNA - ASC diff [nTPM]":"41.6","Cell RNA - ASC TERT1 [nTPM]":"30.5","Cell RNA - BEWO [nTPM]":"26.5","Cell RNA - BJ [nTPM]":"26.6","Cell RNA - BJ hTERT+ [nTPM]":"18.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"34.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"38.7","Cell RNA - CACO-2 [nTPM]":"52.8","Cell RNA - CAPAN-2 [nTPM]":"56.7","Cell RNA - Daudi [nTPM]":"85.4","Cell RNA - EFO-21 [nTPM]":"46.0","Cell RNA - fHDF\/TERT166 [nTPM]":"28.7","Cell RNA - GAMG [nTPM]":"42.6","Cell RNA - HaCaT [nTPM]":"41.0","Cell RNA - HAP1 [nTPM]":"65.7","Cell RNA - HBEC3-KT [nTPM]":"34.2","Cell RNA - HBF TERT88 [nTPM]":"38.9","Cell RNA - HDLM-2 [nTPM]":"27.3","Cell RNA - HEK 293 [nTPM]":"30.2","Cell RNA - HEL [nTPM]":"51.9","Cell RNA - HeLa [nTPM]":"17.9","Cell RNA - Hep G2 [nTPM]":"39.2","Cell RNA - HHSteC [nTPM]":"29.0","Cell RNA - HL-60 [nTPM]":"64.9","Cell RNA - HMC-1 [nTPM]":"26.6","Cell RNA - HSkMC [nTPM]":"36.9","Cell RNA - hTCEpi [nTPM]":"37.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.0","Cell RNA - hTERT-HME1 [nTPM]":"35.2","Cell RNA - hTERT-RPE1 [nTPM]":"24.2","Cell RNA - HUVEC TERT2 [nTPM]":"33.9","Cell RNA - JURKAT [nTPM]":"41.7","Cell RNA - K-562 [nTPM]":"88.4","Cell RNA - Karpas-707 [nTPM]":"42.6","Cell RNA - LHCN-M2 [nTPM]":"41.2","Cell RNA - MCF7 [nTPM]":"16.6","Cell RNA - MOLT-4 [nTPM]":"25.4","Cell RNA - NB-4 [nTPM]":"66.9","Cell RNA - NTERA-2 [nTPM]":"30.3","Cell RNA - OE19 [nTPM]":"58.6","Cell RNA - PC-3 [nTPM]":"35.4","Cell RNA - REH [nTPM]":"45.4","Cell RNA - RH-30 [nTPM]":"38.0","Cell RNA - RPMI-8226 [nTPM]":"93.3","Cell RNA - RPTEC TERT1 [nTPM]":"64.4","Cell RNA - RT4 [nTPM]":"21.4","Cell RNA - SCLC-21H [nTPM]":"51.2","Cell RNA - SH-SY5Y [nTPM]":"27.8","Cell RNA - SiHa [nTPM]":"30.7","Cell RNA - SK-BR-3 [nTPM]":"93.4","Cell RNA - SK-MEL-30 [nTPM]":"20.5","Cell RNA - SuSa [nTPM]":"30.9","Cell RNA - T-47d [nTPM]":"67.4","Cell RNA - THP-1 [nTPM]":"42.9","Cell RNA - TIME [nTPM]":"17.8","Cell RNA - U-138 MG [nTPM]":"29.1","Cell RNA - U-2 OS [nTPM]":"29.1","Cell RNA - U-2197 [nTPM]":"29.1","Cell RNA - U-251 MG [nTPM]":"33.0","Cell RNA - U-266\/70 [nTPM]":"11.1","Cell RNA - U-266\/84 [nTPM]":"19.4","Cell RNA - U-698 [nTPM]":"127.5","Cell RNA - U-87 MG [nTPM]":"7.7","Cell RNA - U-937 [nTPM]":"73.0","Cell RNA - WM-115 [nTPM]":"22.7","Blood RNA - basophil [nTPM]":"9.1","Blood RNA - classical monocyte [nTPM]":"3.8","Blood RNA - eosinophil [nTPM]":"3.0","Blood RNA - gdT-cell [nTPM]":"4.3","Blood RNA - intermediate monocyte [nTPM]":"5.8","Blood RNA - MAIT T-cell [nTPM]":"5.4","Blood RNA - memory B-cell [nTPM]":"5.6","Blood RNA - memory CD4 T-cell [nTPM]":"4.9","Blood RNA - memory CD8 T-cell [nTPM]":"5.1","Blood RNA - myeloid DC [nTPM]":"5.8","Blood RNA - naive B-cell [nTPM]":"4.0","Blood RNA - naive CD4 T-cell [nTPM]":"5.6","Blood RNA - naive CD8 T-cell [nTPM]":"5.1","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"4.7","Blood RNA - non-classical monocyte [nTPM]":"6.1","Blood RNA - plasmacytoid DC [nTPM]":"4.5","Blood RNA - T-reg [nTPM]":"5.8","Blood RNA - total PBMC [nTPM]":"5.0","Brain RNA - amygdala [nTPM]":"7.7","Brain RNA - basal ganglia [nTPM]":"8.3","Brain RNA - cerebellum [nTPM]":"9.5","Brain RNA - cerebral cortex [nTPM]":"9.3","Brain RNA - hippocampal formation [nTPM]":"8.1","Brain RNA - hypothalamus [nTPM]":"11.1","Brain RNA - medulla oblongata [nTPM]":"8.3","Brain RNA - midbrain [nTPM]":"8.9","Brain RNA - pons [nTPM]":"9.7","Brain RNA - spinal cord [nTPM]":"8.2","Brain RNA - thalamus [nTPM]":"9.4","Brain RNA - white matter [nTPM]":"8.0","Single Cell Type RNA - Adipocytes [nTPM]":"7.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.5","Single Cell Type RNA - Astrocytes [nTPM]":"15.3","Single Cell Type RNA - B-cells [nTPM]":"13.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"8.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"100.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"13.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"21.2","Single Cell Type RNA - dendritic cells [nTPM]":"6.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"26.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"74.3","Single Cell Type RNA - Ductal cells [nTPM]":"18.7","Single Cell Type RNA - Early spermatids [nTPM]":"3.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.6","Single Cell Type RNA - Endothelial cells [nTPM]":"9.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.3","Single Cell Type RNA - Erythroid cells [nTPM]":"18.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"39.6","Single Cell Type RNA - Fibroblasts [nTPM]":"11.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.1","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"13.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"15.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.7","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.8","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"8.8","Single Cell Type RNA - Langerhans cells [nTPM]":"7.5","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"6.2","Single Cell Type RNA - Macrophages [nTPM]":"9.5","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"16.7","Single Cell Type RNA - Muller glia cells [nTPM]":"10.4","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.1","Single Cell Type RNA - Paneth cells [nTPM]":"9.2","Single Cell Type RNA - Peritubular cells [nTPM]":"10.9","Single Cell Type RNA - Plasma cells [nTPM]":"19.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"19.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"37.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"30.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.9","Single Cell Type RNA - Spermatocytes [nTPM]":"25.1","Single Cell Type RNA - Spermatogonia [nTPM]":"18.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.4","Single Cell Type RNA - T-cells [nTPM]":"8.5","Single Cell Type RNA - Theca cells [nTPM]":"26.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.7","Single Cell Type RNA - Urothelial cells [nTPM]":"9.3"},{"Gene":"DLD","Gene synonym":["DLDH","E3","GCSL","LAD","OGDC-E3"],"Ensembl":"ENSG00000091140","Gene description":"Dihydrolipoamide dehydrogenase","Uniprot":["P09622"],"Chromosome":"7","Position":"107891162-107931730","Protein class":["Citric acid cycle related proteins","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"tongue":"357.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"356.2","Distal tubular cells":"226.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044849"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"10000000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA044849":"AB_2679111"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.58e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Tissue RNA - adipose tissue [nTPM]":"108.7","Tissue RNA - adrenal gland [nTPM]":"98.9","Tissue RNA - amygdala [nTPM]":"22.7","Tissue RNA - appendix [nTPM]":"42.1","Tissue RNA - basal ganglia [nTPM]":"23.7","Tissue RNA - bone marrow [nTPM]":"54.0","Tissue RNA - breast [nTPM]":"49.0","Tissue RNA - cerebellum [nTPM]":"27.1","Tissue RNA - cerebral cortex [nTPM]":"29.1","Tissue RNA - cervix [nTPM]":"36.3","Tissue RNA - choroid plexus [nTPM]":"35.6","Tissue RNA - colon [nTPM]":"109.0","Tissue RNA - duodenum [nTPM]":"81.8","Tissue RNA - endometrium 1 [nTPM]":"45.3","Tissue RNA - epididymis [nTPM]":"21.2","Tissue RNA - esophagus [nTPM]":"94.1","Tissue RNA - fallopian tube [nTPM]":"34.3","Tissue RNA - gallbladder [nTPM]":"48.5","Tissue RNA - heart muscle [nTPM]":"264.1","Tissue RNA - hippocampal formation [nTPM]":"23.1","Tissue RNA - hypothalamus [nTPM]":"29.5","Tissue RNA - kidney [nTPM]":"153.3","Tissue RNA - liver [nTPM]":"112.8","Tissue RNA - lung [nTPM]":"39.3","Tissue RNA - lymph node [nTPM]":"50.1","Tissue RNA - medulla oblongata [nTPM]":"27.1","Tissue RNA - midbrain [nTPM]":"27.4","Tissue RNA - ovary [nTPM]":"30.0","Tissue RNA - pancreas [nTPM]":"49.2","Tissue RNA - parathyroid gland [nTPM]":"136.7","Tissue RNA - pituitary gland [nTPM]":"27.8","Tissue RNA - placenta [nTPM]":"43.1","Tissue RNA - pons [nTPM]":"26.6","Tissue RNA - prostate [nTPM]":"45.7","Tissue RNA - rectum [nTPM]":"99.3","Tissue RNA - retina [nTPM]":"35.0","Tissue RNA - salivary gland [nTPM]":"50.2","Tissue RNA - seminal vesicle [nTPM]":"50.3","Tissue RNA - skeletal muscle [nTPM]":"295.0","Tissue RNA - skin 1 [nTPM]":"38.9","Tissue RNA - small intestine [nTPM]":"71.9","Tissue RNA - smooth muscle [nTPM]":"67.7","Tissue RNA - spinal cord [nTPM]":"24.9","Tissue RNA - spleen [nTPM]":"38.4","Tissue RNA - stomach 1 [nTPM]":"80.5","Tissue RNA - testis [nTPM]":"31.3","Tissue RNA - thalamus [nTPM]":"25.7","Tissue RNA - thymus [nTPM]":"43.2","Tissue RNA - thyroid gland [nTPM]":"64.2","Tissue RNA - tongue [nTPM]":"357.0","Tissue RNA - tonsil [nTPM]":"67.5","Tissue RNA - urinary bladder [nTPM]":"66.1","Tissue RNA - vagina [nTPM]":"32.7","Tissue RNA - white matter [nTPM]":"23.4","Cell RNA - A-431 [nTPM]":"171.4","Cell RNA - A549 [nTPM]":"134.5","Cell RNA - AF22 [nTPM]":"74.8","Cell RNA - AN3-CA [nTPM]":"127.9","Cell RNA - ASC diff [nTPM]":"104.6","Cell RNA - ASC TERT1 [nTPM]":"91.4","Cell RNA - BEWO [nTPM]":"88.4","Cell RNA - BJ [nTPM]":"96.5","Cell RNA - BJ hTERT+ [nTPM]":"80.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"110.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"86.2","Cell RNA - CACO-2 [nTPM]":"159.5","Cell RNA - CAPAN-2 [nTPM]":"95.5","Cell RNA - Daudi [nTPM]":"165.9","Cell RNA - EFO-21 [nTPM]":"159.6","Cell RNA - fHDF\/TERT166 [nTPM]":"103.0","Cell RNA - GAMG [nTPM]":"177.7","Cell RNA - HaCaT [nTPM]":"110.9","Cell RNA - HAP1 [nTPM]":"150.2","Cell RNA - HBEC3-KT [nTPM]":"135.8","Cell RNA - HBF TERT88 [nTPM]":"166.1","Cell RNA - HDLM-2 [nTPM]":"111.1","Cell RNA - HEK 293 [nTPM]":"88.4","Cell RNA - HEL [nTPM]":"116.9","Cell RNA - HeLa [nTPM]":"175.6","Cell RNA - Hep G2 [nTPM]":"116.7","Cell RNA - HHSteC [nTPM]":"80.3","Cell RNA - HL-60 [nTPM]":"194.7","Cell RNA - HMC-1 [nTPM]":"116.0","Cell RNA - HSkMC [nTPM]":"104.8","Cell RNA - hTCEpi [nTPM]":"97.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"116.4","Cell RNA - hTERT-HME1 [nTPM]":"63.4","Cell RNA - hTERT-RPE1 [nTPM]":"72.3","Cell RNA - HUVEC TERT2 [nTPM]":"134.0","Cell RNA - JURKAT [nTPM]":"137.0","Cell RNA - K-562 [nTPM]":"298.5","Cell RNA - Karpas-707 [nTPM]":"119.7","Cell RNA - LHCN-M2 [nTPM]":"121.8","Cell RNA - MCF7 [nTPM]":"188.1","Cell RNA - MOLT-4 [nTPM]":"161.8","Cell RNA - NB-4 [nTPM]":"138.9","Cell RNA - NTERA-2 [nTPM]":"87.4","Cell RNA - OE19 [nTPM]":"206.0","Cell RNA - PC-3 [nTPM]":"98.2","Cell RNA - REH [nTPM]":"113.1","Cell RNA - RH-30 [nTPM]":"117.8","Cell RNA - RPMI-8226 [nTPM]":"225.9","Cell RNA - RPTEC TERT1 [nTPM]":"151.8","Cell RNA - RT4 [nTPM]":"250.8","Cell RNA - SCLC-21H [nTPM]":"92.3","Cell RNA - SH-SY5Y [nTPM]":"99.9","Cell RNA - SiHa [nTPM]":"156.3","Cell RNA - SK-BR-3 [nTPM]":"262.1","Cell RNA - SK-MEL-30 [nTPM]":"143.9","Cell RNA - SuSa [nTPM]":"149.9","Cell RNA - T-47d [nTPM]":"100.5","Cell RNA - THP-1 [nTPM]":"165.8","Cell RNA - TIME [nTPM]":"87.9","Cell RNA - U-138 MG [nTPM]":"120.7","Cell RNA - U-2 OS [nTPM]":"97.3","Cell RNA - U-2197 [nTPM]":"238.1","Cell RNA - U-251 MG [nTPM]":"149.4","Cell RNA - U-266\/70 [nTPM]":"89.3","Cell RNA - U-266\/84 [nTPM]":"187.1","Cell RNA - U-698 [nTPM]":"114.6","Cell RNA - U-87 MG [nTPM]":"115.0","Cell RNA - U-937 [nTPM]":"204.1","Cell RNA - WM-115 [nTPM]":"130.2","Blood RNA - basophil [nTPM]":"132.7","Blood RNA - classical monocyte [nTPM]":"63.9","Blood RNA - eosinophil [nTPM]":"136.0","Blood RNA - gdT-cell [nTPM]":"46.9","Blood RNA - intermediate monocyte [nTPM]":"81.6","Blood RNA - MAIT T-cell [nTPM]":"49.4","Blood RNA - memory B-cell [nTPM]":"37.8","Blood RNA - memory CD4 T-cell [nTPM]":"46.8","Blood RNA - memory CD8 T-cell [nTPM]":"46.8","Blood RNA - myeloid DC [nTPM]":"87.2","Blood RNA - naive B-cell [nTPM]":"38.5","Blood RNA - naive CD4 T-cell [nTPM]":"47.9","Blood RNA - naive CD8 T-cell [nTPM]":"50.5","Blood RNA - neutrophil [nTPM]":"39.9","Blood RNA - NK-cell [nTPM]":"68.1","Blood RNA - non-classical monocyte [nTPM]":"116.9","Blood RNA - plasmacytoid DC [nTPM]":"29.9","Blood RNA - T-reg [nTPM]":"49.0","Blood RNA - total PBMC [nTPM]":"64.2","Brain RNA - amygdala [nTPM]":"22.7","Brain RNA - basal ganglia [nTPM]":"23.7","Brain RNA - cerebellum [nTPM]":"27.1","Brain RNA - cerebral cortex [nTPM]":"29.1","Brain RNA - hippocampal formation [nTPM]":"23.1","Brain RNA - hypothalamus [nTPM]":"29.5","Brain RNA - medulla oblongata [nTPM]":"27.1","Brain RNA - midbrain [nTPM]":"27.4","Brain RNA - pons [nTPM]":"26.6","Brain RNA - spinal cord [nTPM]":"24.9","Brain RNA - thalamus [nTPM]":"25.7","Brain RNA - white matter [nTPM]":"23.4","Single Cell Type RNA - Adipocytes [nTPM]":"26.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.7","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"26.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"31.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"42.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"124.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.3","Single Cell Type RNA - Bipolar cells [nTPM]":"47.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"24.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"19.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"356.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"51.5","Single Cell Type RNA - Club cells [nTPM]":"70.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"79.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"110.2","Single Cell Type RNA - dendritic cells [nTPM]":"27.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"56.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"226.9","Single Cell Type RNA - Ductal cells [nTPM]":"69.3","Single Cell Type RNA - Early spermatids [nTPM]":"10.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.2","Single Cell Type RNA - Endothelial cells [nTPM]":"32.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"30.6","Single Cell Type RNA - Erythroid cells [nTPM]":"53.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"55.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"62.7","Single Cell Type RNA - Fibroblasts [nTPM]":"36.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"36.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"28.0","Single Cell Type RNA - granulocytes [nTPM]":"26.6","Single Cell Type RNA - Granulosa cells [nTPM]":"35.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.0","Single Cell Type RNA - Hepatocytes [nTPM]":"86.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"69.2","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"44.1","Single Cell Type RNA - Ionocytes [nTPM]":"114.0","Single Cell Type RNA - Kupffer cells [nTPM]":"41.0","Single Cell Type RNA - Langerhans cells [nTPM]":"26.5","Single Cell Type RNA - Late spermatids [nTPM]":"7.3","Single Cell Type RNA - Leydig cells [nTPM]":"23.3","Single Cell Type RNA - Macrophages [nTPM]":"37.5","Single Cell Type RNA - Melanocytes [nTPM]":"37.4","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"62.2","Single Cell Type RNA - Muller glia cells [nTPM]":"36.0","Single Cell Type RNA - NK-cells [nTPM]":"38.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"21.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"42.6","Single Cell Type RNA - Paneth cells [nTPM]":"51.4","Single Cell Type RNA - Peritubular cells [nTPM]":"42.2","Single Cell Type RNA - Plasma cells [nTPM]":"30.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"24.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"60.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"178.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"55.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"45.5","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"28.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"44.8","Single Cell Type RNA - Spermatocytes [nTPM]":"55.2","Single Cell Type RNA - Spermatogonia [nTPM]":"51.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"48.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"32.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"108.4","Single Cell Type RNA - T-cells [nTPM]":"29.5","Single Cell Type RNA - Theca cells [nTPM]":"73.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"78.7","Single Cell Type RNA - Urothelial cells [nTPM]":"39.2"},{"Gene":"DLG4","Gene synonym":["PSD-95","PSD95","SAP-90","SAP90"],"Ensembl":"ENSG00000132535","Gene description":"Discs large MAGUK scaffold protein 4","Uniprot":["P78352"],"Chromosome":"17","Position":"7187187-7219841","Protein class":["Disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"112.4","pituitary gland":"62.8","retina":"223.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"41.8","Cone photoreceptor cells":"102.2","Rod photoreceptor cells":"62.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"13.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"40.0","hTERT-RPE1":"45.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB001999","CAB002000","HPA010122","HPA071006"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB001999":null,"CAB002000":null,"HPA010122":"AB_1855169","HPA071006":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.82e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.70e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-3"},"Tissue RNA - adipose tissue [nTPM]":"13.1","Tissue RNA - adrenal gland [nTPM]":"19.1","Tissue RNA - amygdala [nTPM]":"41.9","Tissue RNA - appendix [nTPM]":"9.3","Tissue RNA - basal ganglia [nTPM]":"49.6","Tissue RNA - bone marrow [nTPM]":"3.6","Tissue RNA - breast [nTPM]":"10.0","Tissue RNA - cerebellum [nTPM]":"32.1","Tissue RNA - cerebral cortex [nTPM]":"112.4","Tissue RNA - cervix [nTPM]":"23.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"18.5","Tissue RNA - duodenum [nTPM]":"4.9","Tissue RNA - endometrium 1 [nTPM]":"23.1","Tissue RNA - epididymis [nTPM]":"6.9","Tissue RNA - esophagus [nTPM]":"6.3","Tissue RNA - fallopian tube [nTPM]":"20.7","Tissue RNA - gallbladder [nTPM]":"10.8","Tissue RNA - heart muscle [nTPM]":"19.6","Tissue RNA - hippocampal formation [nTPM]":"86.3","Tissue RNA - hypothalamus [nTPM]":"17.5","Tissue RNA - kidney [nTPM]":"10.3","Tissue RNA - liver [nTPM]":"7.1","Tissue RNA - lung [nTPM]":"14.7","Tissue RNA - lymph node [nTPM]":"4.4","Tissue RNA - medulla oblongata [nTPM]":"7.2","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"30.3","Tissue RNA - pancreas [nTPM]":"6.3","Tissue RNA - parathyroid gland [nTPM]":"7.2","Tissue RNA - pituitary gland [nTPM]":"62.8","Tissue RNA - placenta [nTPM]":"8.9","Tissue RNA - pons [nTPM]":"5.6","Tissue RNA - prostate [nTPM]":"16.6","Tissue RNA - rectum [nTPM]":"3.5","Tissue RNA - retina [nTPM]":"223.2","Tissue RNA - salivary gland [nTPM]":"7.2","Tissue RNA - seminal vesicle [nTPM]":"12.8","Tissue RNA - skeletal muscle [nTPM]":"6.1","Tissue RNA - skin 1 [nTPM]":"4.7","Tissue RNA - small intestine [nTPM]":"8.4","Tissue RNA - smooth muscle [nTPM]":"11.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"13.9","Tissue RNA - stomach 1 [nTPM]":"10.3","Tissue RNA - testis [nTPM]":"18.9","Tissue RNA - thalamus [nTPM]":"7.7","Tissue RNA - thymus [nTPM]":"8.7","Tissue RNA - thyroid gland [nTPM]":"11.0","Tissue RNA - tongue [nTPM]":"2.8","Tissue RNA - tonsil [nTPM]":"2.9","Tissue RNA - urinary bladder [nTPM]":"13.3","Tissue RNA - vagina [nTPM]":"16.4","Tissue RNA - white matter [nTPM]":"36.2","Cell RNA - A-431 [nTPM]":"0.5","Cell RNA - A549 [nTPM]":"15.2","Cell RNA - AF22 [nTPM]":"29.4","Cell RNA - AN3-CA [nTPM]":"9.1","Cell RNA - ASC diff [nTPM]":"8.4","Cell RNA - ASC TERT1 [nTPM]":"14.6","Cell RNA - BEWO [nTPM]":"1.5","Cell RNA - BJ [nTPM]":"14.1","Cell RNA - BJ hTERT+ [nTPM]":"12.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.3","Cell RNA - CACO-2 [nTPM]":"0.7","Cell RNA - CAPAN-2 [nTPM]":"4.0","Cell RNA - Daudi [nTPM]":"2.4","Cell RNA - EFO-21 [nTPM]":"6.4","Cell RNA - fHDF\/TERT166 [nTPM]":"12.1","Cell RNA - GAMG [nTPM]":"1.6","Cell RNA - HaCaT [nTPM]":"1.8","Cell RNA - HAP1 [nTPM]":"1.1","Cell RNA - HBEC3-KT [nTPM]":"6.7","Cell RNA - HBF TERT88 [nTPM]":"3.3","Cell RNA - HDLM-2 [nTPM]":"17.6","Cell RNA - HEK 293 [nTPM]":"6.0","Cell RNA - HEL [nTPM]":"9.4","Cell RNA - HeLa [nTPM]":"35.1","Cell RNA - Hep G2 [nTPM]":"1.4","Cell RNA - HHSteC [nTPM]":"8.0","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"40.0","Cell RNA - HSkMC [nTPM]":"17.5","Cell RNA - hTCEpi [nTPM]":"0.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.7","Cell RNA - hTERT-HME1 [nTPM]":"11.0","Cell RNA - hTERT-RPE1 [nTPM]":"45.5","Cell RNA - HUVEC TERT2 [nTPM]":"11.5","Cell RNA - JURKAT [nTPM]":"10.1","Cell RNA - K-562 [nTPM]":"3.1","Cell RNA - Karpas-707 [nTPM]":"10.1","Cell RNA - LHCN-M2 [nTPM]":"15.2","Cell RNA - MCF7 [nTPM]":"1.0","Cell RNA - MOLT-4 [nTPM]":"9.3","Cell RNA - NB-4 [nTPM]":"5.1","Cell RNA - NTERA-2 [nTPM]":"3.8","Cell RNA - OE19 [nTPM]":"0.8","Cell RNA - PC-3 [nTPM]":"1.6","Cell RNA - REH [nTPM]":"10.5","Cell RNA - RH-30 [nTPM]":"1.6","Cell RNA - RPMI-8226 [nTPM]":"1.0","Cell RNA - RPTEC TERT1 [nTPM]":"6.6","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"12.4","Cell RNA - SH-SY5Y [nTPM]":"10.5","Cell RNA - SiHa [nTPM]":"0.4","Cell RNA - SK-BR-3 [nTPM]":"0.8","Cell RNA - SK-MEL-30 [nTPM]":"2.6","Cell RNA - SuSa [nTPM]":"7.0","Cell RNA - T-47d [nTPM]":"6.5","Cell RNA - THP-1 [nTPM]":"7.2","Cell RNA - TIME [nTPM]":"16.4","Cell RNA - U-138 MG [nTPM]":"30.6","Cell RNA - U-2 OS [nTPM]":"12.6","Cell RNA - U-2197 [nTPM]":"7.4","Cell RNA - U-251 MG [nTPM]":"7.8","Cell RNA - U-266\/70 [nTPM]":"1.5","Cell RNA - U-266\/84 [nTPM]":"0.9","Cell RNA - U-698 [nTPM]":"2.1","Cell RNA - U-87 MG [nTPM]":"19.3","Cell RNA - U-937 [nTPM]":"6.9","Cell RNA - WM-115 [nTPM]":"8.5","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"41.9","Brain RNA - basal ganglia [nTPM]":"49.6","Brain RNA - cerebellum [nTPM]":"32.1","Brain RNA - cerebral cortex [nTPM]":"112.4","Brain RNA - hippocampal formation [nTPM]":"86.3","Brain RNA - hypothalamus [nTPM]":"17.5","Brain RNA - medulla oblongata [nTPM]":"7.2","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"5.6","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"7.7","Brain RNA - white matter [nTPM]":"36.2","Single Cell Type RNA - Adipocytes [nTPM]":"3.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.5","Single Cell Type RNA - Astrocytes [nTPM]":"14.0","Single Cell Type RNA - B-cells [nTPM]":"1.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"41.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"2.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"102.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.6","Single Cell Type RNA - dendritic cells [nTPM]":"3.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.9","Single Cell Type RNA - Early spermatids [nTPM]":"1.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.5","Single Cell Type RNA - Endothelial cells [nTPM]":"7.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"5.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.2","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.0","Single Cell Type RNA - Hepatocytes [nTPM]":"2.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.9","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.8","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"11.0","Single Cell Type RNA - Langerhans cells [nTPM]":"10.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"7.8","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"5.5","Single Cell Type RNA - Muller glia cells [nTPM]":"11.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"10.1","Single Cell Type RNA - Plasma cells [nTPM]":"0.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"62.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.5","Single Cell Type RNA - Spermatocytes [nTPM]":"6.5","Single Cell Type RNA - Spermatogonia [nTPM]":"2.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"6.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.5","Single Cell Type RNA - Urothelial cells [nTPM]":"1.1"},{"Gene":"DLST","Gene synonym":["DLTS","KGD2","OGDC-E2"],"Ensembl":"ENSG00000119689","Gene description":"Dihydrolipoamide S-succinyltransferase","Uniprot":["P36957"],"Chromosome":"14","Position":"74881891-74903743","Protein class":["Citric acid cycle related proteins","Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Tricarboxylic acid cycle"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003010"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"70000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Mitochondria","Cytosol"],"Antibody RRID":{"HPA003010":"AB_1078679"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.13e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-3"},"Tissue RNA - adipose tissue [nTPM]":"64.5","Tissue RNA - adrenal gland [nTPM]":"85.5","Tissue RNA - amygdala [nTPM]":"33.5","Tissue RNA - appendix [nTPM]":"32.3","Tissue RNA - basal ganglia [nTPM]":"34.7","Tissue RNA - bone marrow [nTPM]":"75.0","Tissue RNA - breast [nTPM]":"59.6","Tissue RNA - cerebellum [nTPM]":"35.8","Tissue RNA - cerebral cortex [nTPM]":"34.7","Tissue RNA - cervix [nTPM]":"62.1","Tissue RNA - choroid plexus [nTPM]":"43.8","Tissue RNA - colon [nTPM]":"63.3","Tissue RNA - duodenum [nTPM]":"58.7","Tissue RNA - endometrium 1 [nTPM]":"47.5","Tissue RNA - epididymis [nTPM]":"43.2","Tissue RNA - esophagus [nTPM]":"62.9","Tissue RNA - fallopian tube [nTPM]":"46.1","Tissue RNA - gallbladder [nTPM]":"36.2","Tissue RNA - heart muscle [nTPM]":"129.0","Tissue RNA - hippocampal formation [nTPM]":"30.8","Tissue RNA - hypothalamus [nTPM]":"35.1","Tissue RNA - kidney [nTPM]":"100.4","Tissue RNA - liver [nTPM]":"78.4","Tissue RNA - lung [nTPM]":"48.5","Tissue RNA - lymph node [nTPM]":"36.9","Tissue RNA - medulla oblongata [nTPM]":"35.8","Tissue RNA - midbrain [nTPM]":"34.5","Tissue RNA - ovary [nTPM]":"45.8","Tissue RNA - pancreas [nTPM]":"44.8","Tissue RNA - parathyroid gland [nTPM]":"78.8","Tissue RNA - pituitary gland [nTPM]":"35.4","Tissue RNA - placenta [nTPM]":"44.8","Tissue RNA - pons [nTPM]":"34.3","Tissue RNA - prostate [nTPM]":"41.3","Tissue RNA - rectum [nTPM]":"59.3","Tissue RNA - retina [nTPM]":"37.1","Tissue RNA - salivary gland [nTPM]":"46.5","Tissue RNA - seminal vesicle [nTPM]":"43.5","Tissue RNA - skeletal muscle [nTPM]":"144.7","Tissue RNA - skin 1 [nTPM]":"64.3","Tissue RNA - small intestine [nTPM]":"58.3","Tissue RNA - smooth muscle [nTPM]":"52.1","Tissue RNA - spinal cord [nTPM]":"33.6","Tissue RNA - spleen [nTPM]":"46.1","Tissue RNA - stomach 1 [nTPM]":"57.7","Tissue RNA - testis [nTPM]":"29.3","Tissue RNA - thalamus [nTPM]":"37.3","Tissue RNA - thymus [nTPM]":"42.5","Tissue RNA - thyroid gland [nTPM]":"42.9","Tissue RNA - tongue [nTPM]":"224.2","Tissue RNA - tonsil [nTPM]":"45.7","Tissue RNA - urinary bladder [nTPM]":"58.0","Tissue RNA - vagina [nTPM]":"49.7","Tissue RNA - white matter [nTPM]":"32.5","Cell RNA - A-431 [nTPM]":"79.1","Cell RNA - A549 [nTPM]":"81.1","Cell RNA - AF22 [nTPM]":"63.7","Cell RNA - AN3-CA [nTPM]":"45.4","Cell RNA - ASC diff [nTPM]":"98.1","Cell RNA - ASC TERT1 [nTPM]":"110.6","Cell RNA - BEWO [nTPM]":"97.5","Cell RNA - BJ [nTPM]":"106.3","Cell RNA - BJ hTERT+ [nTPM]":"107.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"106.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"99.0","Cell RNA - CACO-2 [nTPM]":"80.9","Cell RNA - CAPAN-2 [nTPM]":"88.1","Cell RNA - Daudi [nTPM]":"81.0","Cell RNA - EFO-21 [nTPM]":"44.3","Cell RNA - fHDF\/TERT166 [nTPM]":"118.1","Cell RNA - GAMG [nTPM]":"48.1","Cell RNA - HaCaT [nTPM]":"87.8","Cell RNA - HAP1 [nTPM]":"109.0","Cell RNA - HBEC3-KT [nTPM]":"105.6","Cell RNA - HBF TERT88 [nTPM]":"112.0","Cell RNA - HDLM-2 [nTPM]":"61.5","Cell RNA - HEK 293 [nTPM]":"43.3","Cell RNA - HEL [nTPM]":"68.4","Cell RNA - HeLa [nTPM]":"66.3","Cell RNA - Hep G2 [nTPM]":"74.8","Cell RNA - HHSteC [nTPM]":"101.4","Cell RNA - HL-60 [nTPM]":"49.5","Cell RNA - HMC-1 [nTPM]":"45.4","Cell RNA - HSkMC [nTPM]":"114.0","Cell RNA - hTCEpi [nTPM]":"90.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"103.8","Cell RNA - hTERT-HME1 [nTPM]":"126.7","Cell RNA - hTERT-RPE1 [nTPM]":"95.5","Cell RNA - HUVEC TERT2 [nTPM]":"106.1","Cell RNA - JURKAT [nTPM]":"36.6","Cell RNA - K-562 [nTPM]":"53.4","Cell RNA - Karpas-707 [nTPM]":"55.6","Cell RNA - LHCN-M2 [nTPM]":"110.3","Cell RNA - MCF7 [nTPM]":"112.0","Cell RNA - MOLT-4 [nTPM]":"59.0","Cell RNA - NB-4 [nTPM]":"69.7","Cell RNA - NTERA-2 [nTPM]":"55.0","Cell RNA - OE19 [nTPM]":"146.6","Cell RNA - PC-3 [nTPM]":"79.0","Cell RNA - REH [nTPM]":"73.8","Cell RNA - RH-30 [nTPM]":"93.8","Cell RNA - RPMI-8226 [nTPM]":"46.7","Cell RNA - RPTEC TERT1 [nTPM]":"125.8","Cell RNA - RT4 [nTPM]":"100.8","Cell RNA - SCLC-21H [nTPM]":"75.5","Cell RNA - SH-SY5Y [nTPM]":"64.1","Cell RNA - SiHa [nTPM]":"100.6","Cell RNA - SK-BR-3 [nTPM]":"129.4","Cell RNA - SK-MEL-30 [nTPM]":"71.3","Cell RNA - SuSa [nTPM]":"54.2","Cell RNA - T-47d [nTPM]":"121.7","Cell RNA - THP-1 [nTPM]":"70.5","Cell RNA - TIME [nTPM]":"90.8","Cell RNA - U-138 MG [nTPM]":"63.8","Cell RNA - U-2 OS [nTPM]":"83.2","Cell RNA - U-2197 [nTPM]":"79.5","Cell RNA - U-251 MG [nTPM]":"74.0","Cell RNA - U-266\/70 [nTPM]":"38.7","Cell RNA - U-266\/84 [nTPM]":"43.7","Cell RNA - U-698 [nTPM]":"73.4","Cell RNA - U-87 MG [nTPM]":"93.9","Cell RNA - U-937 [nTPM]":"47.9","Cell RNA - WM-115 [nTPM]":"68.8","Blood RNA - basophil [nTPM]":"3.0","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"2.3","Blood RNA - gdT-cell [nTPM]":"2.1","Blood RNA - intermediate monocyte [nTPM]":"2.0","Blood RNA - MAIT T-cell [nTPM]":"1.8","Blood RNA - memory B-cell [nTPM]":"1.6","Blood RNA - memory CD4 T-cell [nTPM]":"1.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.6","Blood RNA - myeloid DC [nTPM]":"2.1","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.5","Blood RNA - naive CD8 T-cell [nTPM]":"2.2","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"3.5","Blood RNA - non-classical monocyte [nTPM]":"1.8","Blood RNA - plasmacytoid DC [nTPM]":"2.8","Blood RNA - T-reg [nTPM]":"2.0","Blood RNA - total PBMC [nTPM]":"1.5","Brain RNA - amygdala [nTPM]":"33.5","Brain RNA - basal ganglia [nTPM]":"34.7","Brain RNA - cerebellum [nTPM]":"35.8","Brain RNA - cerebral cortex [nTPM]":"34.7","Brain RNA - hippocampal formation [nTPM]":"30.8","Brain RNA - hypothalamus [nTPM]":"35.1","Brain RNA - medulla oblongata [nTPM]":"35.8","Brain RNA - midbrain [nTPM]":"34.5","Brain RNA - pons [nTPM]":"34.3","Brain RNA - spinal cord [nTPM]":"33.6","Brain RNA - thalamus [nTPM]":"37.3","Brain RNA - white matter [nTPM]":"32.5","Single Cell Type RNA - Adipocytes [nTPM]":"24.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"14.0","Single Cell Type RNA - B-cells [nTPM]":"22.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"26.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"19.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.6","Single Cell Type RNA - Bipolar cells [nTPM]":"19.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"28.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"10.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"41.0","Single Cell Type RNA - dendritic cells [nTPM]":"27.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"41.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"56.7","Single Cell Type RNA - Ductal cells [nTPM]":"37.8","Single Cell Type RNA - Early spermatids [nTPM]":"7.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.4","Single Cell Type RNA - Endothelial cells [nTPM]":"19.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.8","Single Cell Type RNA - Erythroid cells [nTPM]":"22.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"21.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"38.8","Single Cell Type RNA - Fibroblasts [nTPM]":"25.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"30.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.9","Single Cell Type RNA - granulocytes [nTPM]":"21.0","Single Cell Type RNA - Granulosa cells [nTPM]":"19.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.2","Single Cell Type RNA - Hepatocytes [nTPM]":"43.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"32.1","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.8","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"20.9","Single Cell Type RNA - Langerhans cells [nTPM]":"19.0","Single Cell Type RNA - Late spermatids [nTPM]":"6.2","Single Cell Type RNA - Leydig cells [nTPM]":"18.0","Single Cell Type RNA - Macrophages [nTPM]":"18.8","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"27.1","Single Cell Type RNA - Muller glia cells [nTPM]":"10.0","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"44.3","Single Cell Type RNA - Paneth cells [nTPM]":"28.0","Single Cell Type RNA - Peritubular cells [nTPM]":"20.7","Single Cell Type RNA - Plasma cells [nTPM]":"20.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"28.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"49.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"73.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"20.8","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"24.0","Single Cell Type RNA - Spermatocytes [nTPM]":"12.1","Single Cell Type RNA - Spermatogonia [nTPM]":"15.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"34.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"28.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"79.5","Single Cell Type RNA - T-cells [nTPM]":"23.1","Single Cell Type RNA - Theca cells [nTPM]":"19.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"40.5","Single Cell Type RNA - Urothelial cells [nTPM]":"27.7"},{"Gene":"DMGDH","Gene synonym":[],"Ensembl":"ENSG00000132837","Gene description":"Dimethylglycine dehydrogenase","Uniprot":["Q9UI17"],"Chromosome":"5","Position":"78997564-79236038","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"18","RNA tissue specific nTPM":{"kidney":"169.4","liver":"283.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"40.6","Hepatocytes":"104.2","Late spermatids":"33.1","Proximal tubular cells":"83.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"liver cancer":"15.6","renal cancer":"12.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+":"3.6","Hep G2":"7.6","hTEC\/SVTERT24-B":"2.2","Karpas-707":"2.3"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036441","HPA036442","HPA077849"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"680000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA036441":"AB_2675124","HPA036442":"AB_10669792","HPA077849":"AB_2686859"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.32e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.17e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.75e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Tissue RNA - adipose tissue [nTPM]":"8.4","Tissue RNA - adrenal gland [nTPM]":"4.5","Tissue RNA - amygdala [nTPM]":"1.5","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"1.7","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"2.2","Tissue RNA - cerebellum [nTPM]":"1.4","Tissue RNA - cerebral cortex [nTPM]":"1.6","Tissue RNA - cervix [nTPM]":"1.4","Tissue RNA - choroid plexus [nTPM]":"3.0","Tissue RNA - colon [nTPM]":"1.3","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"2.8","Tissue RNA - epididymis [nTPM]":"12.2","Tissue RNA - esophagus [nTPM]":"1.4","Tissue RNA - fallopian tube [nTPM]":"1.3","Tissue RNA - gallbladder [nTPM]":"2.1","Tissue RNA - heart muscle [nTPM]":"1.9","Tissue RNA - hippocampal formation [nTPM]":"1.5","Tissue RNA - hypothalamus [nTPM]":"2.4","Tissue RNA - kidney [nTPM]":"169.4","Tissue RNA - liver [nTPM]":"283.8","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"1.5","Tissue RNA - midbrain [nTPM]":"1.9","Tissue RNA - ovary [nTPM]":"2.2","Tissue RNA - pancreas [nTPM]":"1.8","Tissue RNA - parathyroid gland [nTPM]":"0.6","Tissue RNA - pituitary gland [nTPM]":"2.9","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"2.0","Tissue RNA - prostate [nTPM]":"1.8","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"1.8","Tissue RNA - skeletal muscle [nTPM]":"2.4","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"0.6","Tissue RNA - smooth muscle [nTPM]":"1.7","Tissue RNA - spinal cord [nTPM]":"1.4","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"1.0","Tissue RNA - testis [nTPM]":"2.3","Tissue RNA - thalamus [nTPM]":"2.9","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"4.8","Tissue RNA - tongue [nTPM]":"1.5","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"1.2","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"1.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.3","Cell RNA - ASC TERT1 [nTPM]":"0.8","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"3.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.4","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"1.1","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"1.1","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"7.6","Cell RNA - HHSteC [nTPM]":"1.9","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"1.7","Cell RNA - hTCEpi [nTPM]":"2.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.2","Cell RNA - hTERT-HME1 [nTPM]":"1.6","Cell RNA - hTERT-RPE1 [nTPM]":"1.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.8","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"2.3","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"1.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"2.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.5","Brain RNA - basal ganglia [nTPM]":"1.7","Brain RNA - cerebellum [nTPM]":"1.4","Brain RNA - cerebral cortex [nTPM]":"1.6","Brain RNA - hippocampal formation [nTPM]":"1.5","Brain RNA - hypothalamus [nTPM]":"2.4","Brain RNA - medulla oblongata [nTPM]":"1.5","Brain RNA - midbrain [nTPM]":"1.9","Brain RNA - pons [nTPM]":"2.0","Brain RNA - spinal cord [nTPM]":"1.4","Brain RNA - thalamus [nTPM]":"2.9","Brain RNA - white matter [nTPM]":"1.6","Single Cell Type RNA - Adipocytes [nTPM]":"1.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"19.9","Single Cell Type RNA - B-cells [nTPM]":"2.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"1.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"0.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"1.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"40.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"6.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"2.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"4.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"104.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.2","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"33.1","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"1.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"4.3","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.8","Single Cell Type RNA - Paneth cells [nTPM]":"1.4","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"4.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"83.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"4.9","Single Cell Type RNA - Spermatogonia [nTPM]":"5.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"2.9","Single Cell Type RNA - Theca cells [nTPM]":"4.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.9","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"DMPK","Gene synonym":["DM","DM1","DM1PK","DMK","MDPK","MT-PK"],"Ensembl":"ENSG00000104936","Gene description":"DM1 protein kinase","Uniprot":["Q09013"],"Chromosome":"19","Position":"45769709-45782552","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cataract"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"44.1","Sertoli cells":"59.2","Smooth muscle cells":"34.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RH-30":"85.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"8.7"},"Antibody":["HPA007164","HPA008905"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA007164":"AB_1078687","HPA008905":"AB_1078685"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.39e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-3"},"Tissue RNA - adipose tissue [nTPM]":"24.2","Tissue RNA - adrenal gland [nTPM]":"68.3","Tissue RNA - amygdala [nTPM]":"22.1","Tissue RNA - appendix [nTPM]":"17.5","Tissue RNA - basal ganglia [nTPM]":"24.0","Tissue RNA - bone marrow [nTPM]":"3.0","Tissue RNA - breast [nTPM]":"19.1","Tissue RNA - cerebellum [nTPM]":"22.2","Tissue RNA - cerebral cortex [nTPM]":"33.1","Tissue RNA - cervix [nTPM]":"42.8","Tissue RNA - choroid plexus [nTPM]":"25.6","Tissue RNA - colon [nTPM]":"121.5","Tissue RNA - duodenum [nTPM]":"15.8","Tissue RNA - endometrium 1 [nTPM]":"92.7","Tissue RNA - epididymis [nTPM]":"5.3","Tissue RNA - esophagus [nTPM]":"33.4","Tissue RNA - fallopian tube [nTPM]":"61.2","Tissue RNA - gallbladder [nTPM]":"13.9","Tissue RNA - heart muscle [nTPM]":"171.3","Tissue RNA - hippocampal formation [nTPM]":"21.8","Tissue RNA - hypothalamus [nTPM]":"21.6","Tissue RNA - kidney [nTPM]":"20.3","Tissue RNA - liver [nTPM]":"8.8","Tissue RNA - lung [nTPM]":"29.8","Tissue RNA - lymph node [nTPM]":"5.2","Tissue RNA - medulla oblongata [nTPM]":"24.0","Tissue RNA - midbrain [nTPM]":"23.8","Tissue RNA - ovary [nTPM]":"31.1","Tissue RNA - pancreas [nTPM]":"34.3","Tissue RNA - parathyroid gland [nTPM]":"2.9","Tissue RNA - pituitary gland [nTPM]":"37.9","Tissue RNA - placenta [nTPM]":"8.8","Tissue RNA - pons [nTPM]":"22.3","Tissue RNA - prostate [nTPM]":"56.4","Tissue RNA - rectum [nTPM]":"4.8","Tissue RNA - retina [nTPM]":"4.1","Tissue RNA - salivary gland [nTPM]":"18.6","Tissue RNA - seminal vesicle [nTPM]":"37.6","Tissue RNA - skeletal muscle [nTPM]":"173.6","Tissue RNA - skin 1 [nTPM]":"12.3","Tissue RNA - small intestine [nTPM]":"34.6","Tissue RNA - smooth muscle [nTPM]":"59.9","Tissue RNA - spinal cord [nTPM]":"21.9","Tissue RNA - spleen [nTPM]":"17.8","Tissue RNA - stomach 1 [nTPM]":"51.7","Tissue RNA - testis [nTPM]":"13.2","Tissue RNA - thalamus [nTPM]":"23.8","Tissue RNA - thymus [nTPM]":"4.2","Tissue RNA - thyroid gland [nTPM]":"21.7","Tissue RNA - tongue [nTPM]":"143.2","Tissue RNA - tonsil [nTPM]":"1.3","Tissue RNA - urinary bladder [nTPM]":"69.1","Tissue RNA - vagina [nTPM]":"34.3","Tissue RNA - white matter [nTPM]":"21.3","Cell RNA - A-431 [nTPM]":"11.7","Cell RNA - A549 [nTPM]":"16.7","Cell RNA - AF22 [nTPM]":"13.5","Cell RNA - AN3-CA [nTPM]":"10.7","Cell RNA - ASC diff [nTPM]":"13.4","Cell RNA - ASC TERT1 [nTPM]":"12.9","Cell RNA - BEWO [nTPM]":"10.5","Cell RNA - BJ [nTPM]":"26.1","Cell RNA - BJ hTERT+ [nTPM]":"22.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.8","Cell RNA - CACO-2 [nTPM]":"2.2","Cell RNA - CAPAN-2 [nTPM]":"6.6","Cell RNA - Daudi [nTPM]":"2.9","Cell RNA - EFO-21 [nTPM]":"2.8","Cell RNA - fHDF\/TERT166 [nTPM]":"32.9","Cell RNA - GAMG [nTPM]":"9.2","Cell RNA - HaCaT [nTPM]":"15.1","Cell RNA - HAP1 [nTPM]":"3.0","Cell RNA - HBEC3-KT [nTPM]":"1.5","Cell RNA - HBF TERT88 [nTPM]":"2.2","Cell RNA - HDLM-2 [nTPM]":"12.4","Cell RNA - HEK 293 [nTPM]":"16.6","Cell RNA - HEL [nTPM]":"0.8","Cell RNA - HeLa [nTPM]":"22.6","Cell RNA - Hep G2 [nTPM]":"1.4","Cell RNA - HHSteC [nTPM]":"12.6","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"5.4","Cell RNA - HSkMC [nTPM]":"22.8","Cell RNA - hTCEpi [nTPM]":"8.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.4","Cell RNA - hTERT-HME1 [nTPM]":"1.7","Cell RNA - hTERT-RPE1 [nTPM]":"24.2","Cell RNA - HUVEC TERT2 [nTPM]":"3.6","Cell RNA - JURKAT [nTPM]":"2.1","Cell RNA - K-562 [nTPM]":"8.6","Cell RNA - Karpas-707 [nTPM]":"8.0","Cell RNA - LHCN-M2 [nTPM]":"15.4","Cell RNA - MCF7 [nTPM]":"13.7","Cell RNA - MOLT-4 [nTPM]":"1.6","Cell RNA - NB-4 [nTPM]":"3.8","Cell RNA - NTERA-2 [nTPM]":"8.8","Cell RNA - OE19 [nTPM]":"4.8","Cell RNA - PC-3 [nTPM]":"3.3","Cell RNA - REH [nTPM]":"5.0","Cell RNA - RH-30 [nTPM]":"85.1","Cell RNA - RPMI-8226 [nTPM]":"6.4","Cell RNA - RPTEC TERT1 [nTPM]":"4.7","Cell RNA - RT4 [nTPM]":"11.5","Cell RNA - SCLC-21H [nTPM]":"10.2","Cell RNA - SH-SY5Y [nTPM]":"13.5","Cell RNA - SiHa [nTPM]":"13.6","Cell RNA - SK-BR-3 [nTPM]":"27.6","Cell RNA - SK-MEL-30 [nTPM]":"9.3","Cell RNA - SuSa [nTPM]":"4.8","Cell RNA - T-47d [nTPM]":"28.6","Cell RNA - THP-1 [nTPM]":"5.5","Cell RNA - TIME [nTPM]":"8.4","Cell RNA - U-138 MG [nTPM]":"9.2","Cell RNA - U-2 OS [nTPM]":"10.4","Cell RNA - U-2197 [nTPM]":"8.3","Cell RNA - U-251 MG [nTPM]":"15.0","Cell RNA - U-266\/70 [nTPM]":"16.8","Cell RNA - U-266\/84 [nTPM]":"11.5","Cell RNA - U-698 [nTPM]":"2.9","Cell RNA - U-87 MG [nTPM]":"9.5","Cell RNA - U-937 [nTPM]":"1.3","Cell RNA - WM-115 [nTPM]":"13.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"22.1","Brain RNA - basal ganglia [nTPM]":"24.0","Brain RNA - cerebellum [nTPM]":"22.2","Brain RNA - cerebral cortex [nTPM]":"33.1","Brain RNA - hippocampal formation [nTPM]":"21.8","Brain RNA - hypothalamus [nTPM]":"21.6","Brain RNA - medulla oblongata [nTPM]":"24.0","Brain RNA - midbrain [nTPM]":"23.8","Brain RNA - pons [nTPM]":"22.3","Brain RNA - spinal cord [nTPM]":"21.9","Brain RNA - thalamus [nTPM]":"23.8","Brain RNA - white matter [nTPM]":"21.3","Single Cell Type RNA - Adipocytes [nTPM]":"10.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.2","Single Cell Type RNA - Astrocytes [nTPM]":"44.1","Single Cell Type RNA - B-cells [nTPM]":"3.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"5.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"3.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.7","Single Cell Type RNA - dendritic cells [nTPM]":"4.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.7","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.6","Single Cell Type RNA - Endothelial cells [nTPM]":"7.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.1","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.0","Single Cell Type RNA - Fibroblasts [nTPM]":"8.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"9.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.3","Single Cell Type RNA - Hepatocytes [nTPM]":"1.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.8","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.2","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"9.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.8","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"0.4","Single Cell Type RNA - Muller glia cells [nTPM]":"2.6","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"26.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.8","Single Cell Type RNA - Paneth cells [nTPM]":"4.5","Single Cell Type RNA - Peritubular cells [nTPM]":"23.3","Single Cell Type RNA - Plasma cells [nTPM]":"3.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"31.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.4","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"34.9","Single Cell Type RNA - Spermatocytes [nTPM]":"7.2","Single Cell Type RNA - Spermatogonia [nTPM]":"6.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.6","Single Cell Type RNA - T-cells [nTPM]":"4.5","Single Cell Type RNA - Theca cells [nTPM]":"5.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.1","Single Cell Type RNA - Urothelial cells [nTPM]":"4.6"},{"Gene":"DMXL2","Gene synonym":["DFNA71","KIAA0856","RC3"],"Ensembl":"ENSG00000104093","Gene description":"Dmx like 2","Uniprot":["Q8TDJ6"],"Chromosome":"15","Position":"51447711-51622833","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Diabetes mellitus","Disease variant","Epilepsy","Hypogonadotropic hypogonadism","Neuropathy","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"138.9","Inhibitory neurons":"122.9","Kupffer cells":"96.1","Macrophages":"106.3","monocytes":"84.9","Oligodendrocyte precursor cells":"96.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"2.8","intermediate monocyte":"2.2","neutrophil":"2.2","non-classical monocyte":"2.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"2.2","monocytes":"2.8"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-937":"44.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039375"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039375":"AB_10673610"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.50e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.3","Tissue RNA - adrenal gland [nTPM]":"4.7","Tissue RNA - amygdala [nTPM]":"4.1","Tissue RNA - appendix [nTPM]":"11.1","Tissue RNA - basal ganglia [nTPM]":"4.7","Tissue RNA - bone marrow [nTPM]":"17.1","Tissue RNA - breast [nTPM]":"3.4","Tissue RNA - cerebellum [nTPM]":"4.0","Tissue RNA - cerebral cortex [nTPM]":"7.3","Tissue RNA - cervix [nTPM]":"4.6","Tissue RNA - choroid plexus [nTPM]":"8.1","Tissue RNA - colon [nTPM]":"6.5","Tissue RNA - duodenum [nTPM]":"9.2","Tissue RNA - endometrium 1 [nTPM]":"4.4","Tissue RNA - epididymis [nTPM]":"13.9","Tissue RNA - esophagus [nTPM]":"1.9","Tissue RNA - fallopian tube [nTPM]":"5.2","Tissue RNA - gallbladder [nTPM]":"4.5","Tissue RNA - heart muscle [nTPM]":"3.1","Tissue RNA - hippocampal formation [nTPM]":"8.9","Tissue RNA - hypothalamus [nTPM]":"2.8","Tissue RNA - kidney [nTPM]":"5.7","Tissue RNA - liver [nTPM]":"4.5","Tissue RNA - lung [nTPM]":"6.8","Tissue RNA - lymph node [nTPM]":"4.7","Tissue RNA - medulla oblongata [nTPM]":"2.5","Tissue RNA - midbrain [nTPM]":"1.1","Tissue RNA - ovary [nTPM]":"4.1","Tissue RNA - pancreas [nTPM]":"5.4","Tissue RNA - parathyroid gland [nTPM]":"8.0","Tissue RNA - pituitary gland [nTPM]":"8.4","Tissue RNA - placenta [nTPM]":"7.2","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"2.7","Tissue RNA - rectum [nTPM]":"7.5","Tissue RNA - retina [nTPM]":"16.3","Tissue RNA - salivary gland [nTPM]":"5.4","Tissue RNA - seminal vesicle [nTPM]":"2.5","Tissue RNA - skeletal muscle [nTPM]":"1.1","Tissue RNA - skin 1 [nTPM]":"1.7","Tissue RNA - small intestine [nTPM]":"7.1","Tissue RNA - smooth muscle [nTPM]":"5.3","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"6.5","Tissue RNA - stomach 1 [nTPM]":"5.3","Tissue RNA - testis [nTPM]":"9.0","Tissue RNA - thalamus [nTPM]":"4.2","Tissue RNA - thymus [nTPM]":"4.7","Tissue RNA - thyroid gland [nTPM]":"4.2","Tissue RNA - tongue [nTPM]":"1.7","Tissue RNA - tonsil [nTPM]":"2.6","Tissue RNA - urinary bladder [nTPM]":"6.0","Tissue RNA - vagina [nTPM]":"2.8","Tissue RNA - white matter [nTPM]":"2.4","Cell RNA - A-431 [nTPM]":"9.1","Cell RNA - A549 [nTPM]":"11.7","Cell RNA - AF22 [nTPM]":"12.6","Cell RNA - AN3-CA [nTPM]":"7.3","Cell RNA - ASC diff [nTPM]":"5.3","Cell RNA - ASC TERT1 [nTPM]":"9.1","Cell RNA - BEWO [nTPM]":"3.1","Cell RNA - BJ [nTPM]":"6.9","Cell RNA - BJ hTERT+ [nTPM]":"7.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.5","Cell RNA - CACO-2 [nTPM]":"1.7","Cell RNA - CAPAN-2 [nTPM]":"4.4","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"3.3","Cell RNA - fHDF\/TERT166 [nTPM]":"4.1","Cell RNA - GAMG [nTPM]":"12.5","Cell RNA - HaCaT [nTPM]":"4.8","Cell RNA - HAP1 [nTPM]":"8.1","Cell RNA - HBEC3-KT [nTPM]":"4.8","Cell RNA - HBF TERT88 [nTPM]":"8.7","Cell RNA - HDLM-2 [nTPM]":"10.6","Cell RNA - HEK 293 [nTPM]":"3.9","Cell RNA - HEL [nTPM]":"3.6","Cell RNA - HeLa [nTPM]":"10.6","Cell RNA - Hep G2 [nTPM]":"2.1","Cell RNA - HHSteC [nTPM]":"4.9","Cell RNA - HL-60 [nTPM]":"20.6","Cell RNA - HMC-1 [nTPM]":"5.8","Cell RNA - HSkMC [nTPM]":"4.2","Cell RNA - hTCEpi [nTPM]":"3.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.4","Cell RNA - hTERT-HME1 [nTPM]":"3.7","Cell RNA - hTERT-RPE1 [nTPM]":"6.8","Cell RNA - HUVEC TERT2 [nTPM]":"4.5","Cell RNA - JURKAT [nTPM]":"10.9","Cell RNA - K-562 [nTPM]":"8.3","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"6.7","Cell RNA - MCF7 [nTPM]":"10.0","Cell RNA - MOLT-4 [nTPM]":"8.9","Cell RNA - NB-4 [nTPM]":"19.2","Cell RNA - NTERA-2 [nTPM]":"9.2","Cell RNA - OE19 [nTPM]":"4.3","Cell RNA - PC-3 [nTPM]":"3.8","Cell RNA - REH [nTPM]":"7.9","Cell RNA - RH-30 [nTPM]":"10.3","Cell RNA - RPMI-8226 [nTPM]":"13.5","Cell RNA - RPTEC TERT1 [nTPM]":"3.4","Cell RNA - RT4 [nTPM]":"18.1","Cell RNA - SCLC-21H [nTPM]":"18.0","Cell RNA - SH-SY5Y [nTPM]":"7.8","Cell RNA - SiHa [nTPM]":"7.3","Cell RNA - SK-BR-3 [nTPM]":"4.1","Cell RNA - SK-MEL-30 [nTPM]":"8.5","Cell RNA - SuSa [nTPM]":"11.0","Cell RNA - T-47d [nTPM]":"6.9","Cell RNA - THP-1 [nTPM]":"21.9","Cell RNA - TIME [nTPM]":"5.7","Cell RNA - U-138 MG [nTPM]":"7.8","Cell RNA - U-2 OS [nTPM]":"5.3","Cell RNA - U-2197 [nTPM]":"11.0","Cell RNA - U-251 MG [nTPM]":"8.2","Cell RNA - U-266\/70 [nTPM]":"16.0","Cell RNA - U-266\/84 [nTPM]":"25.2","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"9.2","Cell RNA - U-937 [nTPM]":"44.0","Cell RNA - WM-115 [nTPM]":"7.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.8","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"2.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"2.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"2.7","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"4.1","Brain RNA - basal ganglia [nTPM]":"4.7","Brain RNA - cerebellum [nTPM]":"4.0","Brain RNA - cerebral cortex [nTPM]":"7.3","Brain RNA - hippocampal formation [nTPM]":"8.9","Brain RNA - hypothalamus [nTPM]":"2.8","Brain RNA - medulla oblongata [nTPM]":"2.5","Brain RNA - midbrain [nTPM]":"1.1","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"4.2","Brain RNA - white matter [nTPM]":"2.4","Single Cell Type RNA - Adipocytes [nTPM]":"5.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.7","Single Cell Type RNA - Astrocytes [nTPM]":"68.6","Single Cell Type RNA - B-cells [nTPM]":"2.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"41.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"6.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"64.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.7","Single Cell Type RNA - dendritic cells [nTPM]":"13.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"22.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.9","Single Cell Type RNA - Endothelial cells [nTPM]":"5.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"28.1","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"138.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.9","Single Cell Type RNA - Fibroblasts [nTPM]":"8.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"28.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.5","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"10.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.7","Single Cell Type RNA - Hepatocytes [nTPM]":"6.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"36.5","Single Cell Type RNA - Horizontal cells [nTPM]":"58.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"122.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.3","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"96.1","Single Cell Type RNA - Langerhans cells [nTPM]":"16.4","Single Cell Type RNA - Late spermatids [nTPM]":"3.5","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"106.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"50.6","Single Cell Type RNA - monocytes [nTPM]":"84.9","Single Cell Type RNA - Muller glia cells [nTPM]":"8.6","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"96.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"50.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.2","Single Cell Type RNA - Paneth cells [nTPM]":"17.4","Single Cell Type RNA - Peritubular cells [nTPM]":"9.1","Single Cell Type RNA - Plasma cells [nTPM]":"2.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"31.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.7","Single Cell Type RNA - Spermatocytes [nTPM]":"37.2","Single Cell Type RNA - Spermatogonia [nTPM]":"30.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.8","Single Cell Type RNA - T-cells [nTPM]":"3.6","Single Cell Type RNA - Theca cells [nTPM]":"9.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.9","Single Cell Type RNA - Urothelial cells [nTPM]":"2.7"},{"Gene":"DNA2","Gene synonym":["DNA2L","KIAA0083"],"Ensembl":"ENSG00000138346","Gene description":"DNA replication helicase\/nuclease 2","Uniprot":["P51530"],"Chromosome":"10","Position":"68414064-68472121","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","DNA replication"],"Molecular function":["DNA-binding","Endonuclease","Helicase","Hydrolase","Multifunctional enzyme","Nuclease"],"Disease involvement":["Disease variant","Dwarfism","Mental retardation","Primary mitochondrial disease","Progressive external ophthalmoplegia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"8.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"33.2","Excitatory neurons":"14.1","Inhibitory neurons":"15.5","Oligodendrocytes":"18.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"NK-cell":"1.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"NK-cells":"1.8"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037487","HPA057526"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA037487":"AB_10672493","HPA057526":"AB_2683456"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.3","Tissue RNA - adrenal gland [nTPM]":"0.9","Tissue RNA - amygdala [nTPM]":"1.9","Tissue RNA - appendix [nTPM]":"2.8","Tissue RNA - basal ganglia [nTPM]":"2.1","Tissue RNA - bone marrow [nTPM]":"4.6","Tissue RNA - breast [nTPM]":"1.8","Tissue RNA - cerebellum [nTPM]":"2.5","Tissue RNA - cerebral cortex [nTPM]":"3.6","Tissue RNA - cervix [nTPM]":"1.4","Tissue RNA - choroid plexus [nTPM]":"1.0","Tissue RNA - colon [nTPM]":"2.3","Tissue RNA - duodenum [nTPM]":"2.1","Tissue RNA - endometrium 1 [nTPM]":"1.1","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"1.9","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"0.9","Tissue RNA - heart muscle [nTPM]":"1.8","Tissue RNA - hippocampal formation [nTPM]":"1.8","Tissue RNA - hypothalamus [nTPM]":"1.9","Tissue RNA - kidney [nTPM]":"2.6","Tissue RNA - liver [nTPM]":"4.2","Tissue RNA - lung [nTPM]":"1.8","Tissue RNA - lymph node [nTPM]":"5.2","Tissue RNA - medulla oblongata [nTPM]":"2.3","Tissue RNA - midbrain [nTPM]":"1.9","Tissue RNA - ovary [nTPM]":"1.2","Tissue RNA - pancreas [nTPM]":"1.6","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"1.5","Tissue RNA - placenta [nTPM]":"1.6","Tissue RNA - pons [nTPM]":"2.4","Tissue RNA - prostate [nTPM]":"1.9","Tissue RNA - rectum [nTPM]":"2.8","Tissue RNA - retina [nTPM]":"5.3","Tissue RNA - salivary gland [nTPM]":"1.6","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"1.6","Tissue RNA - skin 1 [nTPM]":"1.8","Tissue RNA - small intestine [nTPM]":"3.2","Tissue RNA - smooth muscle [nTPM]":"1.1","Tissue RNA - spinal cord [nTPM]":"1.6","Tissue RNA - spleen [nTPM]":"2.1","Tissue RNA - stomach 1 [nTPM]":"1.9","Tissue RNA - testis [nTPM]":"2.9","Tissue RNA - thalamus [nTPM]":"2.1","Tissue RNA - thymus [nTPM]":"8.1","Tissue RNA - thyroid gland [nTPM]":"1.0","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"4.2","Tissue RNA - urinary bladder [nTPM]":"1.4","Tissue RNA - vagina [nTPM]":"1.4","Tissue RNA - white matter [nTPM]":"3.2","Cell RNA - A-431 [nTPM]":"25.6","Cell RNA - A549 [nTPM]":"13.0","Cell RNA - AF22 [nTPM]":"29.0","Cell RNA - AN3-CA [nTPM]":"20.7","Cell RNA - ASC diff [nTPM]":"3.2","Cell RNA - ASC TERT1 [nTPM]":"2.2","Cell RNA - BEWO [nTPM]":"20.4","Cell RNA - BJ [nTPM]":"12.4","Cell RNA - BJ hTERT+ [nTPM]":"10.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.2","Cell RNA - CACO-2 [nTPM]":"31.1","Cell RNA - CAPAN-2 [nTPM]":"16.1","Cell RNA - Daudi [nTPM]":"26.1","Cell RNA - EFO-21 [nTPM]":"4.6","Cell RNA - fHDF\/TERT166 [nTPM]":"3.8","Cell RNA - GAMG [nTPM]":"6.7","Cell RNA - HaCaT [nTPM]":"15.2","Cell RNA - HAP1 [nTPM]":"16.8","Cell RNA - HBEC3-KT [nTPM]":"6.5","Cell RNA - HBF TERT88 [nTPM]":"20.7","Cell RNA - HDLM-2 [nTPM]":"16.2","Cell RNA - HEK 293 [nTPM]":"12.6","Cell RNA - HEL [nTPM]":"15.8","Cell RNA - HeLa [nTPM]":"8.5","Cell RNA - Hep G2 [nTPM]":"12.3","Cell RNA - HHSteC [nTPM]":"0.9","Cell RNA - HL-60 [nTPM]":"27.7","Cell RNA - HMC-1 [nTPM]":"16.4","Cell RNA - HSkMC [nTPM]":"1.8","Cell RNA - hTCEpi [nTPM]":"2.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.3","Cell RNA - hTERT-HME1 [nTPM]":"3.6","Cell RNA - hTERT-RPE1 [nTPM]":"4.5","Cell RNA - HUVEC TERT2 [nTPM]":"7.9","Cell RNA - JURKAT [nTPM]":"17.0","Cell RNA - K-562 [nTPM]":"23.6","Cell RNA - Karpas-707 [nTPM]":"22.8","Cell RNA - LHCN-M2 [nTPM]":"10.1","Cell RNA - MCF7 [nTPM]":"9.0","Cell RNA - MOLT-4 [nTPM]":"42.8","Cell RNA - NB-4 [nTPM]":"19.8","Cell RNA - NTERA-2 [nTPM]":"20.5","Cell RNA - OE19 [nTPM]":"10.9","Cell RNA - PC-3 [nTPM]":"24.0","Cell RNA - REH [nTPM]":"33.1","Cell RNA - RH-30 [nTPM]":"20.0","Cell RNA - RPMI-8226 [nTPM]":"8.4","Cell RNA - RPTEC TERT1 [nTPM]":"7.5","Cell RNA - RT4 [nTPM]":"11.7","Cell RNA - SCLC-21H [nTPM]":"13.1","Cell RNA - SH-SY5Y [nTPM]":"15.7","Cell RNA - SiHa [nTPM]":"16.9","Cell RNA - SK-BR-3 [nTPM]":"21.4","Cell RNA - SK-MEL-30 [nTPM]":"4.2","Cell RNA - SuSa [nTPM]":"20.1","Cell RNA - T-47d [nTPM]":"16.5","Cell RNA - THP-1 [nTPM]":"11.6","Cell RNA - TIME [nTPM]":"3.4","Cell RNA - U-138 MG [nTPM]":"6.6","Cell RNA - U-2 OS [nTPM]":"20.5","Cell RNA - U-2197 [nTPM]":"8.5","Cell RNA - U-251 MG [nTPM]":"23.8","Cell RNA - U-266\/70 [nTPM]":"11.5","Cell RNA - U-266\/84 [nTPM]":"13.9","Cell RNA - U-698 [nTPM]":"38.3","Cell RNA - U-87 MG [nTPM]":"5.7","Cell RNA - U-937 [nTPM]":"26.1","Cell RNA - WM-115 [nTPM]":"8.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.9","Brain RNA - basal ganglia [nTPM]":"2.1","Brain RNA - cerebellum [nTPM]":"2.5","Brain RNA - cerebral cortex [nTPM]":"3.6","Brain RNA - hippocampal formation [nTPM]":"1.8","Brain RNA - hypothalamus [nTPM]":"1.9","Brain RNA - medulla oblongata [nTPM]":"2.3","Brain RNA - midbrain [nTPM]":"1.9","Brain RNA - pons [nTPM]":"2.4","Brain RNA - spinal cord [nTPM]":"1.6","Brain RNA - thalamus [nTPM]":"2.1","Brain RNA - white matter [nTPM]":"3.2","Single Cell Type RNA - Adipocytes [nTPM]":"1.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"4.9","Single Cell Type RNA - B-cells [nTPM]":"1.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"2.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"1.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.9","Single Cell Type RNA - dendritic cells [nTPM]":"2.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"2.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.4","Single Cell Type RNA - Endothelial cells [nTPM]":"2.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"33.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.8","Single Cell Type RNA - Fibroblasts [nTPM]":"2.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"6.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"4.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"3.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"1.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"0.5","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"7.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.1","Single Cell Type RNA - Spermatocytes [nTPM]":"9.1","Single Cell Type RNA - Spermatogonia [nTPM]":"12.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - T-cells [nTPM]":"1.6","Single Cell Type RNA - Theca cells [nTPM]":"0.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.7","Single Cell Type RNA - Urothelial cells [nTPM]":"1.0"},{"Gene":"DNAJC6","Gene synonym":["KIAA0473","PARK19"],"Ensembl":"ENSG00000116675","Gene description":"DnaJ heat shock protein family (Hsp40) member C6","Uniprot":["O75061"],"Chromosome":"1","Position":"65248219-65415871","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Chaperone","Hydrolase","Protein phosphatase"],"Disease involvement":["Disease variant","Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"81.5","retina":"52.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Oligodendrocytes":"1038.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"5.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"62.1","HEL":"165.8","K-562":"65.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031182","HPA054917"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm","Plasma membrane"],"Antibody RRID":{"HPA031182":"AB_10611957","HPA054917":"AB_2682641"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-7"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.81e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-3"},"Tissue RNA - adipose tissue [nTPM]":"1.5","Tissue RNA - adrenal gland [nTPM]":"11.1","Tissue RNA - amygdala [nTPM]":"34.7","Tissue RNA - appendix [nTPM]":"0.9","Tissue RNA - basal ganglia [nTPM]":"43.3","Tissue RNA - bone marrow [nTPM]":"4.7","Tissue RNA - breast [nTPM]":"1.1","Tissue RNA - cerebellum [nTPM]":"33.7","Tissue RNA - cerebral cortex [nTPM]":"46.9","Tissue RNA - cervix [nTPM]":"0.8","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"2.1","Tissue RNA - duodenum [nTPM]":"1.0","Tissue RNA - endometrium 1 [nTPM]":"0.6","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"1.1","Tissue RNA - gallbladder [nTPM]":"1.0","Tissue RNA - heart muscle [nTPM]":"8.9","Tissue RNA - hippocampal formation [nTPM]":"42.1","Tissue RNA - hypothalamus [nTPM]":"48.0","Tissue RNA - kidney [nTPM]":"7.7","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"1.5","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"60.2","Tissue RNA - midbrain [nTPM]":"51.3","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"2.1","Tissue RNA - parathyroid gland [nTPM]":"1.0","Tissue RNA - pituitary gland [nTPM]":"12.6","Tissue RNA - placenta [nTPM]":"7.4","Tissue RNA - pons [nTPM]":"67.6","Tissue RNA - prostate [nTPM]":"1.1","Tissue RNA - rectum [nTPM]":"1.7","Tissue RNA - retina [nTPM]":"52.8","Tissue RNA - salivary gland [nTPM]":"0.7","Tissue RNA - seminal vesicle [nTPM]":"0.7","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"1.1","Tissue RNA - small intestine [nTPM]":"1.0","Tissue RNA - smooth muscle [nTPM]":"0.9","Tissue RNA - spinal cord [nTPM]":"27.2","Tissue RNA - spleen [nTPM]":"2.1","Tissue RNA - stomach 1 [nTPM]":"1.7","Tissue RNA - testis [nTPM]":"2.2","Tissue RNA - thalamus [nTPM]":"42.0","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"1.7","Tissue RNA - tongue [nTPM]":"0.8","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"1.1","Tissue RNA - vagina [nTPM]":"0.9","Tissue RNA - white matter [nTPM]":"81.5","Cell RNA - A-431 [nTPM]":"10.4","Cell RNA - A549 [nTPM]":"2.8","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"4.4","Cell RNA - ASC diff [nTPM]":"2.1","Cell RNA - ASC TERT1 [nTPM]":"0.5","Cell RNA - BEWO [nTPM]":"23.4","Cell RNA - BJ [nTPM]":"20.1","Cell RNA - BJ hTERT+ [nTPM]":"33.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"32.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"31.7","Cell RNA - CACO-2 [nTPM]":"2.7","Cell RNA - CAPAN-2 [nTPM]":"0.5","Cell RNA - Daudi [nTPM]":"9.9","Cell RNA - EFO-21 [nTPM]":"1.7","Cell RNA - fHDF\/TERT166 [nTPM]":"8.3","Cell RNA - GAMG [nTPM]":"8.0","Cell RNA - HaCaT [nTPM]":"2.5","Cell RNA - HAP1 [nTPM]":"14.6","Cell RNA - HBEC3-KT [nTPM]":"3.3","Cell RNA - HBF TERT88 [nTPM]":"25.8","Cell RNA - HDLM-2 [nTPM]":"62.1","Cell RNA - HEK 293 [nTPM]":"6.9","Cell RNA - HEL [nTPM]":"165.8","Cell RNA - HeLa [nTPM]":"5.1","Cell RNA - Hep G2 [nTPM]":"0.6","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"5.6","Cell RNA - HMC-1 [nTPM]":"3.9","Cell RNA - HSkMC [nTPM]":"2.7","Cell RNA - hTCEpi [nTPM]":"2.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.3","Cell RNA - hTERT-HME1 [nTPM]":"13.8","Cell RNA - hTERT-RPE1 [nTPM]":"6.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.7","Cell RNA - JURKAT [nTPM]":"8.0","Cell RNA - K-562 [nTPM]":"65.5","Cell RNA - Karpas-707 [nTPM]":"1.2","Cell RNA - LHCN-M2 [nTPM]":"6.6","Cell RNA - MCF7 [nTPM]":"1.9","Cell RNA - MOLT-4 [nTPM]":"2.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"6.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"2.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"4.9","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"23.7","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"39.4","Cell RNA - SH-SY5Y [nTPM]":"27.0","Cell RNA - SiHa [nTPM]":"11.9","Cell RNA - SK-BR-3 [nTPM]":"15.5","Cell RNA - SK-MEL-30 [nTPM]":"5.4","Cell RNA - SuSa [nTPM]":"37.4","Cell RNA - T-47d [nTPM]":"7.5","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"6.5","Cell RNA - U-138 MG [nTPM]":"4.8","Cell RNA - U-2 OS [nTPM]":"3.3","Cell RNA - U-2197 [nTPM]":"0.6","Cell RNA - U-251 MG [nTPM]":"5.9","Cell RNA - U-266\/70 [nTPM]":"6.0","Cell RNA - U-266\/84 [nTPM]":"4.1","Cell RNA - U-698 [nTPM]":"3.0","Cell RNA - U-87 MG [nTPM]":"13.4","Cell RNA - U-937 [nTPM]":"4.1","Cell RNA - WM-115 [nTPM]":"8.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"34.7","Brain RNA - basal ganglia [nTPM]":"43.3","Brain RNA - cerebellum [nTPM]":"33.7","Brain RNA - cerebral cortex [nTPM]":"46.9","Brain RNA - hippocampal formation [nTPM]":"42.1","Brain RNA - hypothalamus [nTPM]":"48.0","Brain RNA - medulla oblongata [nTPM]":"60.2","Brain RNA - midbrain [nTPM]":"51.3","Brain RNA - pons [nTPM]":"67.6","Brain RNA - spinal cord [nTPM]":"27.2","Brain RNA - thalamus [nTPM]":"42.0","Brain RNA - white matter [nTPM]":"81.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"49.3","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"30.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"28.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.9","Single Cell Type RNA - dendritic cells [nTPM]":"1.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"2.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"3.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"19.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"237.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.1","Single Cell Type RNA - Fibroblasts [nTPM]":"5.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.2","Single Cell Type RNA - Horizontal cells [nTPM]":"52.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"237.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.9","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"1.1","Single Cell Type RNA - Muller glia cells [nTPM]":"4.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"136.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1038.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.5","Single Cell Type RNA - Spermatocytes [nTPM]":"1.7","Single Cell Type RNA - Spermatogonia [nTPM]":"2.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.4","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"6.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"DNASE1","Gene synonym":["DNL1"],"Ensembl":"ENSG00000213918","Gene description":"Deoxyribonuclease 1","Uniprot":["P24855"],"Chromosome":"16","Position":"3611728-3680143","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Apoptosis"],"Molecular function":["Actin-binding","Endonuclease","Hydrolase","Nuclease"],"Disease involvement":["Systemic lupus erythematosus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"34.5","kidney":"34.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Proximal enterocytes":"715.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010703"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"420000","Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA010703":"AB_10600806"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.14e-4"},"Tissue RNA - adipose tissue [nTPM]":"4.6","Tissue RNA - adrenal gland [nTPM]":"5.0","Tissue RNA - amygdala [nTPM]":"5.1","Tissue RNA - appendix [nTPM]":"6.6","Tissue RNA - basal ganglia [nTPM]":"5.6","Tissue RNA - bone marrow [nTPM]":"4.3","Tissue RNA - breast [nTPM]":"4.6","Tissue RNA - cerebellum [nTPM]":"13.4","Tissue RNA - cerebral cortex [nTPM]":"6.4","Tissue RNA - cervix [nTPM]":"9.8","Tissue RNA - choroid plexus [nTPM]":"6.9","Tissue RNA - colon [nTPM]":"6.1","Tissue RNA - duodenum [nTPM]":"29.7","Tissue RNA - endometrium 1 [nTPM]":"5.2","Tissue RNA - epididymis [nTPM]":"5.0","Tissue RNA - esophagus [nTPM]":"7.1","Tissue RNA - fallopian tube [nTPM]":"6.8","Tissue RNA - gallbladder [nTPM]":"2.7","Tissue RNA - heart muscle [nTPM]":"5.5","Tissue RNA - hippocampal formation [nTPM]":"5.8","Tissue RNA - hypothalamus [nTPM]":"4.9","Tissue RNA - kidney [nTPM]":"34.2","Tissue RNA - liver [nTPM]":"5.9","Tissue RNA - lung [nTPM]":"4.9","Tissue RNA - lymph node [nTPM]":"10.0","Tissue RNA - medulla oblongata [nTPM]":"6.0","Tissue RNA - midbrain [nTPM]":"5.2","Tissue RNA - ovary [nTPM]":"7.5","Tissue RNA - pancreas [nTPM]":"23.6","Tissue RNA - parathyroid gland [nTPM]":"2.7","Tissue RNA - pituitary gland [nTPM]":"16.3","Tissue RNA - placenta [nTPM]":"4.2","Tissue RNA - pons [nTPM]":"6.6","Tissue RNA - prostate [nTPM]":"11.6","Tissue RNA - rectum [nTPM]":"5.0","Tissue RNA - retina [nTPM]":"4.4","Tissue RNA - salivary gland [nTPM]":"4.9","Tissue RNA - seminal vesicle [nTPM]":"2.5","Tissue RNA - skeletal muscle [nTPM]":"3.7","Tissue RNA - skin 1 [nTPM]":"7.8","Tissue RNA - small intestine [nTPM]":"34.5","Tissue RNA - smooth muscle [nTPM]":"2.7","Tissue RNA - spinal cord [nTPM]":"3.2","Tissue RNA - spleen [nTPM]":"9.2","Tissue RNA - stomach 1 [nTPM]":"11.2","Tissue RNA - testis [nTPM]":"9.2","Tissue RNA - thalamus [nTPM]":"5.8","Tissue RNA - thymus [nTPM]":"9.4","Tissue RNA - thyroid gland [nTPM]":"7.4","Tissue RNA - tongue [nTPM]":"1.3","Tissue RNA - tonsil [nTPM]":"8.7","Tissue RNA - urinary bladder [nTPM]":"6.0","Tissue RNA - vagina [nTPM]":"8.5","Tissue RNA - white matter [nTPM]":"9.7","Cell RNA - A-431 [nTPM]":"2.9","Cell RNA - A549 [nTPM]":"6.5","Cell RNA - AF22 [nTPM]":"11.4","Cell RNA - AN3-CA [nTPM]":"5.9","Cell RNA - ASC diff [nTPM]":"3.3","Cell RNA - ASC TERT1 [nTPM]":"2.8","Cell RNA - BEWO [nTPM]":"5.2","Cell RNA - BJ [nTPM]":"4.7","Cell RNA - BJ hTERT+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.3","Cell RNA - CACO-2 [nTPM]":"8.0","Cell RNA - CAPAN-2 [nTPM]":"6.9","Cell RNA - Daudi [nTPM]":"12.3","Cell RNA - EFO-21 [nTPM]":"3.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.7","Cell RNA - GAMG [nTPM]":"7.8","Cell RNA - HaCaT [nTPM]":"4.8","Cell RNA - HAP1 [nTPM]":"4.2","Cell RNA - HBEC3-KT [nTPM]":"1.3","Cell RNA - HBF TERT88 [nTPM]":"3.9","Cell RNA - HDLM-2 [nTPM]":"5.5","Cell RNA - HEK 293 [nTPM]":"6.4","Cell RNA - HEL [nTPM]":"4.4","Cell RNA - HeLa [nTPM]":"11.3","Cell RNA - Hep G2 [nTPM]":"5.4","Cell RNA - HHSteC [nTPM]":"1.7","Cell RNA - HL-60 [nTPM]":"2.9","Cell RNA - HMC-1 [nTPM]":"9.6","Cell RNA - HSkMC [nTPM]":"2.3","Cell RNA - hTCEpi [nTPM]":"4.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.0","Cell RNA - hTERT-HME1 [nTPM]":"1.2","Cell RNA - hTERT-RPE1 [nTPM]":"5.8","Cell RNA - HUVEC TERT2 [nTPM]":"2.5","Cell RNA - JURKAT [nTPM]":"10.3","Cell RNA - K-562 [nTPM]":"11.2","Cell RNA - Karpas-707 [nTPM]":"5.0","Cell RNA - LHCN-M2 [nTPM]":"3.2","Cell RNA - MCF7 [nTPM]":"12.3","Cell RNA - MOLT-4 [nTPM]":"6.3","Cell RNA - NB-4 [nTPM]":"13.6","Cell RNA - NTERA-2 [nTPM]":"6.9","Cell RNA - OE19 [nTPM]":"8.7","Cell RNA - PC-3 [nTPM]":"3.6","Cell RNA - REH [nTPM]":"14.9","Cell RNA - RH-30 [nTPM]":"5.3","Cell RNA - RPMI-8226 [nTPM]":"5.7","Cell RNA - RPTEC TERT1 [nTPM]":"3.1","Cell RNA - RT4 [nTPM]":"2.5","Cell RNA - SCLC-21H [nTPM]":"8.1","Cell RNA - SH-SY5Y [nTPM]":"7.6","Cell RNA - SiHa [nTPM]":"3.5","Cell RNA - SK-BR-3 [nTPM]":"10.5","Cell RNA - SK-MEL-30 [nTPM]":"1.9","Cell RNA - SuSa [nTPM]":"5.7","Cell RNA - T-47d [nTPM]":"10.4","Cell RNA - THP-1 [nTPM]":"7.7","Cell RNA - TIME [nTPM]":"3.4","Cell RNA - U-138 MG [nTPM]":"6.8","Cell RNA - U-2 OS [nTPM]":"5.0","Cell RNA - U-2197 [nTPM]":"4.3","Cell RNA - U-251 MG [nTPM]":"2.5","Cell RNA - U-266\/70 [nTPM]":"4.8","Cell RNA - U-266\/84 [nTPM]":"7.5","Cell RNA - U-698 [nTPM]":"21.4","Cell RNA - U-87 MG [nTPM]":"1.7","Cell RNA - U-937 [nTPM]":"5.7","Cell RNA - WM-115 [nTPM]":"6.6","Blood RNA - basophil [nTPM]":"2.7","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"3.2","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"1.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.2","Blood RNA - memory CD8 T-cell [nTPM]":"1.3","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"1.8","Blood RNA - neutrophil [nTPM]":"5.0","Blood RNA - NK-cell [nTPM]":"1.0","Blood RNA - non-classical monocyte [nTPM]":"0.7","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"1.4","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"5.1","Brain RNA - basal ganglia [nTPM]":"5.6","Brain RNA - cerebellum [nTPM]":"13.4","Brain RNA - cerebral cortex [nTPM]":"6.4","Brain RNA - hippocampal formation [nTPM]":"5.8","Brain RNA - hypothalamus [nTPM]":"4.9","Brain RNA - medulla oblongata [nTPM]":"6.0","Brain RNA - midbrain [nTPM]":"5.2","Brain RNA - pons [nTPM]":"6.6","Brain RNA - spinal cord [nTPM]":"3.2","Brain RNA - thalamus [nTPM]":"5.8","Brain RNA - white matter [nTPM]":"9.7","Single Cell Type RNA - Adipocytes [nTPM]":"4.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.3","Single Cell Type RNA - Astrocytes [nTPM]":"27.1","Single Cell Type RNA - B-cells [nTPM]":"9.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"27.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"9.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.6","Single Cell Type RNA - dendritic cells [nTPM]":"9.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"56.7","Single Cell Type RNA - Ductal cells [nTPM]":"5.3","Single Cell Type RNA - Early spermatids [nTPM]":"19.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.0","Single Cell Type RNA - Endothelial cells [nTPM]":"7.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.3","Single Cell Type RNA - Erythroid cells [nTPM]":"7.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"20.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.1","Single Cell Type RNA - Fibroblasts [nTPM]":"7.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.4","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"23.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"1.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.9","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"38.6","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"5.0","Single Cell Type RNA - Langerhans cells [nTPM]":"4.2","Single Cell Type RNA - Late spermatids [nTPM]":"52.4","Single Cell Type RNA - Leydig cells [nTPM]":"8.4","Single Cell Type RNA - Macrophages [nTPM]":"4.4","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"13.2","Single Cell Type RNA - Muller glia cells [nTPM]":"8.6","Single Cell Type RNA - NK-cells [nTPM]":"30.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"22.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.3","Single Cell Type RNA - Paneth cells [nTPM]":"61.4","Single Cell Type RNA - Peritubular cells [nTPM]":"7.9","Single Cell Type RNA - Plasma cells [nTPM]":"7.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"715.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.3","Single Cell Type RNA - Spermatocytes [nTPM]":"28.5","Single Cell Type RNA - Spermatogonia [nTPM]":"24.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.2","Single Cell Type RNA - T-cells [nTPM]":"12.2","Single Cell Type RNA - Theca cells [nTPM]":"10.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"33.4","Single Cell Type RNA - Urothelial cells [nTPM]":"6.3"},{"Gene":"DNM1","Gene synonym":["DNM"],"Ensembl":"ENSG00000106976","Gene description":"Dynamin 1","Uniprot":["Q05193"],"Chromosome":"9","Position":"128191655-128255248","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Endocytosis"],"Molecular function":["Hydrolase","Motor protein"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"319.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"112.4","Cone photoreceptor cells":"89.6","Excitatory neurons":"176.1","Inhibitory neurons":"182.2","Rod photoreceptor cells":"78.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"319.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"126.9","U-87 MG":"46.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005920","HPA049910"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"8800","Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB005920":null,"HPA049910":"AB_2680948"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-3"},"Tissue RNA - adipose tissue [nTPM]":"22.2","Tissue RNA - adrenal gland [nTPM]":"7.9","Tissue RNA - amygdala [nTPM]":"99.8","Tissue RNA - appendix [nTPM]":"3.7","Tissue RNA - basal ganglia [nTPM]":"129.1","Tissue RNA - bone marrow [nTPM]":"2.0","Tissue RNA - breast [nTPM]":"13.2","Tissue RNA - cerebellum [nTPM]":"13.6","Tissue RNA - cerebral cortex [nTPM]":"319.5","Tissue RNA - cervix [nTPM]":"30.8","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"8.0","Tissue RNA - duodenum [nTPM]":"1.9","Tissue RNA - endometrium 1 [nTPM]":"8.8","Tissue RNA - epididymis [nTPM]":"2.4","Tissue RNA - esophagus [nTPM]":"5.5","Tissue RNA - fallopian tube [nTPM]":"9.4","Tissue RNA - gallbladder [nTPM]":"13.4","Tissue RNA - heart muscle [nTPM]":"7.8","Tissue RNA - hippocampal formation [nTPM]":"140.1","Tissue RNA - hypothalamus [nTPM]":"15.9","Tissue RNA - kidney [nTPM]":"14.1","Tissue RNA - liver [nTPM]":"5.3","Tissue RNA - lung [nTPM]":"4.6","Tissue RNA - lymph node [nTPM]":"2.4","Tissue RNA - medulla oblongata [nTPM]":"50.7","Tissue RNA - midbrain [nTPM]":"4.1","Tissue RNA - ovary [nTPM]":"2.5","Tissue RNA - pancreas [nTPM]":"8.4","Tissue RNA - parathyroid gland [nTPM]":"4.1","Tissue RNA - pituitary gland [nTPM]":"33.6","Tissue RNA - placenta [nTPM]":"2.5","Tissue RNA - pons [nTPM]":"36.6","Tissue RNA - prostate [nTPM]":"9.0","Tissue RNA - rectum [nTPM]":"2.7","Tissue RNA - retina [nTPM]":"68.3","Tissue RNA - salivary gland [nTPM]":"9.0","Tissue RNA - seminal vesicle [nTPM]":"3.0","Tissue RNA - skeletal muscle [nTPM]":"3.2","Tissue RNA - skin 1 [nTPM]":"15.0","Tissue RNA - small intestine [nTPM]":"9.0","Tissue RNA - smooth muscle [nTPM]":"5.3","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"1.0","Tissue RNA - stomach 1 [nTPM]":"5.0","Tissue RNA - testis [nTPM]":"4.9","Tissue RNA - thalamus [nTPM]":"10.0","Tissue RNA - thymus [nTPM]":"0.9","Tissue RNA - thyroid gland [nTPM]":"5.2","Tissue RNA - tongue [nTPM]":"4.0","Tissue RNA - tonsil [nTPM]":"1.8","Tissue RNA - urinary bladder [nTPM]":"10.6","Tissue RNA - vagina [nTPM]":"21.6","Tissue RNA - white matter [nTPM]":"123.1","Cell RNA - A-431 [nTPM]":"8.7","Cell RNA - A549 [nTPM]":"126.9","Cell RNA - AF22 [nTPM]":"11.3","Cell RNA - AN3-CA [nTPM]":"2.8","Cell RNA - ASC diff [nTPM]":"3.6","Cell RNA - ASC TERT1 [nTPM]":"36.8","Cell RNA - BEWO [nTPM]":"0.6","Cell RNA - BJ [nTPM]":"8.0","Cell RNA - BJ hTERT+ [nTPM]":"18.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.5","Cell RNA - CACO-2 [nTPM]":"1.7","Cell RNA - CAPAN-2 [nTPM]":"2.6","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"10.7","Cell RNA - fHDF\/TERT166 [nTPM]":"16.7","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"15.3","Cell RNA - HAP1 [nTPM]":"1.8","Cell RNA - HBEC3-KT [nTPM]":"0.8","Cell RNA - HBF TERT88 [nTPM]":"8.6","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"12.1","Cell RNA - HEL [nTPM]":"8.3","Cell RNA - HeLa [nTPM]":"19.5","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"2.6","Cell RNA - HL-60 [nTPM]":"1.1","Cell RNA - HMC-1 [nTPM]":"5.6","Cell RNA - HSkMC [nTPM]":"9.8","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.4","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"15.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"7.3","Cell RNA - K-562 [nTPM]":"3.1","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"3.6","Cell RNA - MOLT-4 [nTPM]":"0.7","Cell RNA - NB-4 [nTPM]":"2.7","Cell RNA - NTERA-2 [nTPM]":"12.2","Cell RNA - OE19 [nTPM]":"2.2","Cell RNA - PC-3 [nTPM]":"23.1","Cell RNA - REH [nTPM]":"15.6","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"3.9","Cell RNA - RPTEC TERT1 [nTPM]":"2.4","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"16.1","Cell RNA - SH-SY5Y [nTPM]":"27.1","Cell RNA - SiHa [nTPM]":"27.1","Cell RNA - SK-BR-3 [nTPM]":"0.8","Cell RNA - SK-MEL-30 [nTPM]":"1.2","Cell RNA - SuSa [nTPM]":"1.4","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"11.2","Cell RNA - TIME [nTPM]":"0.6","Cell RNA - U-138 MG [nTPM]":"0.5","Cell RNA - U-2 OS [nTPM]":"34.8","Cell RNA - U-2197 [nTPM]":"36.2","Cell RNA - U-251 MG [nTPM]":"16.6","Cell RNA - U-266\/70 [nTPM]":"1.0","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.8","Cell RNA - U-87 MG [nTPM]":"46.8","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"2.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"99.8","Brain RNA - basal ganglia [nTPM]":"129.1","Brain RNA - cerebellum [nTPM]":"13.6","Brain RNA - cerebral cortex [nTPM]":"319.5","Brain RNA - hippocampal formation [nTPM]":"140.1","Brain RNA - hypothalamus [nTPM]":"15.9","Brain RNA - medulla oblongata [nTPM]":"50.7","Brain RNA - midbrain [nTPM]":"4.1","Brain RNA - pons [nTPM]":"36.6","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"10.0","Brain RNA - white matter [nTPM]":"123.1","Single Cell Type RNA - Adipocytes [nTPM]":"2.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"18.9","Single Cell Type RNA - B-cells [nTPM]":"0.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"112.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"0.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"89.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"176.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"24.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.4","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"2.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.6","Single Cell Type RNA - Horizontal cells [nTPM]":"50.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"182.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"10.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"9.2","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"22.5","Single Cell Type RNA - monocytes [nTPM]":"1.3","Single Cell Type RNA - Muller glia cells [nTPM]":"10.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"33.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"5.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"0.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"78.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.8","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"1.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"1.6","Single Cell Type RNA - Theca cells [nTPM]":"2.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"DNM1L","Gene synonym":["DRP1","DVLP","DYMPLE","HDYNIV","VPS1"],"Ensembl":"ENSG00000087470","Gene description":"Dynamin 1 like","Uniprot":["O00429"],"Chromosome":"12","Position":"32679200-32745650","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Biological rhythms","Endocytosis","Necrosis"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009952","HPA039324"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2000000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB009952":"AB_2093533","HPA039324":"AB_2676443"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.27e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Tissue RNA - adipose tissue [nTPM]":"23.2","Tissue RNA - adrenal gland [nTPM]":"23.2","Tissue RNA - amygdala [nTPM]":"25.3","Tissue RNA - appendix [nTPM]":"23.5","Tissue RNA - basal ganglia [nTPM]":"27.5","Tissue RNA - bone marrow [nTPM]":"40.0","Tissue RNA - breast [nTPM]":"21.1","Tissue RNA - cerebellum [nTPM]":"27.7","Tissue RNA - cerebral cortex [nTPM]":"32.3","Tissue RNA - cervix [nTPM]":"18.4","Tissue RNA - choroid plexus [nTPM]":"15.7","Tissue RNA - colon [nTPM]":"24.0","Tissue RNA - duodenum [nTPM]":"18.6","Tissue RNA - endometrium 1 [nTPM]":"23.6","Tissue RNA - epididymis [nTPM]":"23.9","Tissue RNA - esophagus [nTPM]":"28.6","Tissue RNA - fallopian tube [nTPM]":"19.8","Tissue RNA - gallbladder [nTPM]":"17.5","Tissue RNA - heart muscle [nTPM]":"38.9","Tissue RNA - hippocampal formation [nTPM]":"28.4","Tissue RNA - hypothalamus [nTPM]":"26.1","Tissue RNA - kidney [nTPM]":"27.9","Tissue RNA - liver [nTPM]":"14.2","Tissue RNA - lung [nTPM]":"16.7","Tissue RNA - lymph node [nTPM]":"20.9","Tissue RNA - medulla oblongata [nTPM]":"22.5","Tissue RNA - midbrain [nTPM]":"22.0","Tissue RNA - ovary [nTPM]":"20.0","Tissue RNA - pancreas [nTPM]":"13.5","Tissue RNA - parathyroid gland [nTPM]":"40.5","Tissue RNA - pituitary gland [nTPM]":"25.3","Tissue RNA - placenta [nTPM]":"23.9","Tissue RNA - pons [nTPM]":"23.6","Tissue RNA - prostate [nTPM]":"27.0","Tissue RNA - rectum [nTPM]":"22.7","Tissue RNA - retina [nTPM]":"44.9","Tissue RNA - salivary gland [nTPM]":"16.0","Tissue RNA - seminal vesicle [nTPM]":"28.7","Tissue RNA - skeletal muscle [nTPM]":"43.8","Tissue RNA - skin 1 [nTPM]":"18.3","Tissue RNA - small intestine [nTPM]":"16.8","Tissue RNA - smooth muscle [nTPM]":"32.0","Tissue RNA - spinal cord [nTPM]":"22.2","Tissue RNA - spleen [nTPM]":"18.8","Tissue RNA - stomach 1 [nTPM]":"17.3","Tissue RNA - testis [nTPM]":"36.0","Tissue RNA - thalamus [nTPM]":"21.6","Tissue RNA - thymus [nTPM]":"21.4","Tissue RNA - thyroid gland [nTPM]":"22.4","Tissue RNA - tongue [nTPM]":"57.2","Tissue RNA - tonsil [nTPM]":"24.8","Tissue RNA - urinary bladder [nTPM]":"29.9","Tissue RNA - vagina [nTPM]":"18.5","Tissue RNA - white matter [nTPM]":"26.6","Cell RNA - A-431 [nTPM]":"66.8","Cell RNA - A549 [nTPM]":"62.3","Cell RNA - AF22 [nTPM]":"64.3","Cell RNA - AN3-CA [nTPM]":"68.3","Cell RNA - ASC diff [nTPM]":"51.2","Cell RNA - ASC TERT1 [nTPM]":"52.7","Cell RNA - BEWO [nTPM]":"123.2","Cell RNA - BJ [nTPM]":"72.0","Cell RNA - BJ hTERT+ [nTPM]":"55.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"67.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"61.7","Cell RNA - CACO-2 [nTPM]":"80.6","Cell RNA - CAPAN-2 [nTPM]":"48.0","Cell RNA - Daudi [nTPM]":"87.3","Cell RNA - EFO-21 [nTPM]":"50.0","Cell RNA - fHDF\/TERT166 [nTPM]":"65.8","Cell RNA - GAMG [nTPM]":"66.9","Cell RNA - HaCaT [nTPM]":"57.8","Cell RNA - HAP1 [nTPM]":"69.2","Cell RNA - HBEC3-KT [nTPM]":"80.3","Cell RNA - HBF TERT88 [nTPM]":"79.3","Cell RNA - HDLM-2 [nTPM]":"46.6","Cell RNA - HEK 293 [nTPM]":"57.6","Cell RNA - HEL [nTPM]":"102.3","Cell RNA - HeLa [nTPM]":"57.2","Cell RNA - Hep G2 [nTPM]":"48.2","Cell RNA - HHSteC [nTPM]":"41.7","Cell RNA - HL-60 [nTPM]":"72.5","Cell RNA - HMC-1 [nTPM]":"50.1","Cell RNA - HSkMC [nTPM]":"48.6","Cell RNA - hTCEpi [nTPM]":"37.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"70.7","Cell RNA - hTERT-HME1 [nTPM]":"66.1","Cell RNA - hTERT-RPE1 [nTPM]":"63.5","Cell RNA - HUVEC TERT2 [nTPM]":"81.1","Cell RNA - JURKAT [nTPM]":"41.4","Cell RNA - K-562 [nTPM]":"74.4","Cell RNA - Karpas-707 [nTPM]":"37.5","Cell RNA - LHCN-M2 [nTPM]":"75.3","Cell RNA - MCF7 [nTPM]":"21.7","Cell RNA - MOLT-4 [nTPM]":"29.1","Cell RNA - NB-4 [nTPM]":"61.7","Cell RNA - NTERA-2 [nTPM]":"138.2","Cell RNA - OE19 [nTPM]":"41.0","Cell RNA - PC-3 [nTPM]":"30.8","Cell RNA - REH [nTPM]":"48.6","Cell RNA - RH-30 [nTPM]":"125.0","Cell RNA - RPMI-8226 [nTPM]":"61.5","Cell RNA - RPTEC TERT1 [nTPM]":"56.5","Cell RNA - RT4 [nTPM]":"79.1","Cell RNA - SCLC-21H [nTPM]":"57.1","Cell RNA - SH-SY5Y [nTPM]":"59.3","Cell RNA - SiHa [nTPM]":"76.3","Cell RNA - SK-BR-3 [nTPM]":"51.8","Cell RNA - SK-MEL-30 [nTPM]":"56.7","Cell RNA - SuSa [nTPM]":"129.4","Cell RNA - T-47d [nTPM]":"59.7","Cell RNA - THP-1 [nTPM]":"49.0","Cell RNA - TIME [nTPM]":"74.0","Cell RNA - U-138 MG [nTPM]":"57.3","Cell RNA - U-2 OS [nTPM]":"54.4","Cell RNA - U-2197 [nTPM]":"135.3","Cell RNA - U-251 MG [nTPM]":"68.2","Cell RNA - U-266\/70 [nTPM]":"26.1","Cell RNA - U-266\/84 [nTPM]":"75.8","Cell RNA - U-698 [nTPM]":"86.3","Cell RNA - U-87 MG [nTPM]":"55.6","Cell RNA - U-937 [nTPM]":"47.0","Cell RNA - WM-115 [nTPM]":"43.5","Blood RNA - basophil [nTPM]":"7.4","Blood RNA - classical monocyte [nTPM]":"10.0","Blood RNA - eosinophil [nTPM]":"3.2","Blood RNA - gdT-cell [nTPM]":"5.6","Blood RNA - intermediate monocyte [nTPM]":"15.6","Blood RNA - MAIT T-cell [nTPM]":"6.9","Blood RNA - memory B-cell [nTPM]":"7.0","Blood RNA - memory CD4 T-cell [nTPM]":"6.2","Blood RNA - memory CD8 T-cell [nTPM]":"6.1","Blood RNA - myeloid DC [nTPM]":"18.8","Blood RNA - naive B-cell [nTPM]":"6.0","Blood RNA - naive CD4 T-cell [nTPM]":"7.3","Blood RNA - naive CD8 T-cell [nTPM]":"8.4","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"8.1","Blood RNA - non-classical monocyte [nTPM]":"15.6","Blood RNA - plasmacytoid DC [nTPM]":"5.6","Blood RNA - T-reg [nTPM]":"7.3","Blood RNA - total PBMC [nTPM]":"7.9","Brain RNA - amygdala [nTPM]":"25.3","Brain RNA - basal ganglia [nTPM]":"27.5","Brain RNA - cerebellum [nTPM]":"27.7","Brain RNA - cerebral cortex [nTPM]":"32.3","Brain RNA - hippocampal formation [nTPM]":"28.4","Brain RNA - hypothalamus [nTPM]":"26.1","Brain RNA - medulla oblongata [nTPM]":"22.5","Brain RNA - midbrain [nTPM]":"22.0","Brain RNA - pons [nTPM]":"23.6","Brain RNA - spinal cord [nTPM]":"22.2","Brain RNA - thalamus [nTPM]":"21.6","Brain RNA - white matter [nTPM]":"26.6","Single Cell Type RNA - Adipocytes [nTPM]":"42.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"38.4","Single Cell Type RNA - Astrocytes [nTPM]":"82.6","Single Cell Type RNA - B-cells [nTPM]":"36.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"34.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"28.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"44.3","Single Cell Type RNA - Bipolar cells [nTPM]":"80.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"32.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"29.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"82.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"33.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"131.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"30.0","Single Cell Type RNA - dendritic cells [nTPM]":"53.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"26.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"31.3","Single Cell Type RNA - Ductal cells [nTPM]":"34.8","Single Cell Type RNA - Early spermatids [nTPM]":"63.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"38.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"55.8","Single Cell Type RNA - Endothelial cells [nTPM]":"42.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"30.5","Single Cell Type RNA - Erythroid cells [nTPM]":"28.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"139.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"63.7","Single Cell Type RNA - Fibroblasts [nTPM]":"41.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"59.4","Single Cell Type RNA - granulocytes [nTPM]":"50.7","Single Cell Type RNA - Granulosa cells [nTPM]":"48.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.4","Single Cell Type RNA - Hepatocytes [nTPM]":"16.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.8","Single Cell Type RNA - Horizontal cells [nTPM]":"126.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"150.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.9","Single Cell Type RNA - Ionocytes [nTPM]":"34.6","Single Cell Type RNA - Kupffer cells [nTPM]":"27.5","Single Cell Type RNA - Langerhans cells [nTPM]":"30.7","Single Cell Type RNA - Late spermatids [nTPM]":"78.0","Single Cell Type RNA - Leydig cells [nTPM]":"26.8","Single Cell Type RNA - Macrophages [nTPM]":"43.3","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"44.0","Single Cell Type RNA - monocytes [nTPM]":"45.6","Single Cell Type RNA - Muller glia cells [nTPM]":"59.0","Single Cell Type RNA - NK-cells [nTPM]":"34.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"99.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"121.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"45.7","Single Cell Type RNA - Paneth cells [nTPM]":"14.4","Single Cell Type RNA - Peritubular cells [nTPM]":"30.5","Single Cell Type RNA - Plasma cells [nTPM]":"48.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"42.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"164.8","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"55.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"55.5","Single Cell Type RNA - Spermatocytes [nTPM]":"79.3","Single Cell Type RNA - Spermatogonia [nTPM]":"52.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"39.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"36.0","Single Cell Type RNA - T-cells [nTPM]":"42.2","Single Cell Type RNA - Theca cells [nTPM]":"26.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"31.5","Single Cell Type RNA - Urothelial cells [nTPM]":"36.4"},{"Gene":"DNM2","Gene synonym":["CMT2M","CMTDI1","CMTDIB","DI-CMTB","DYN2","DYNII"],"Ensembl":"ENSG00000079805","Gene description":"Dynamin 2","Uniprot":["P50570"],"Chromosome":"19","Position":"10718079-10833488","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Endocytosis","Phagocytosis"],"Molecular function":["Hydrolase","Motor protein"],"Disease involvement":["Cancer-related genes","Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"242.8","Paneth cells":"177.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054246"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"230000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Golgi apparatus","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA054246":"AB_2682427"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.91e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.63e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-3"},"Tissue RNA - adipose tissue [nTPM]":"55.1","Tissue RNA - adrenal gland [nTPM]":"69.9","Tissue RNA - amygdala [nTPM]":"50.5","Tissue RNA - appendix [nTPM]":"63.2","Tissue RNA - basal ganglia [nTPM]":"77.8","Tissue RNA - bone marrow [nTPM]":"125.7","Tissue RNA - breast [nTPM]":"46.1","Tissue RNA - cerebellum [nTPM]":"74.1","Tissue RNA - cerebral cortex [nTPM]":"64.1","Tissue RNA - cervix [nTPM]":"49.0","Tissue RNA - choroid plexus [nTPM]":"38.8","Tissue RNA - colon [nTPM]":"105.8","Tissue RNA - duodenum [nTPM]":"65.9","Tissue RNA - endometrium 1 [nTPM]":"42.2","Tissue RNA - epididymis [nTPM]":"25.3","Tissue RNA - esophagus [nTPM]":"67.6","Tissue RNA - fallopian tube [nTPM]":"42.5","Tissue RNA - gallbladder [nTPM]":"40.5","Tissue RNA - heart muscle [nTPM]":"87.2","Tissue RNA - hippocampal formation [nTPM]":"52.3","Tissue RNA - hypothalamus [nTPM]":"57.4","Tissue RNA - kidney [nTPM]":"72.8","Tissue RNA - liver [nTPM]":"57.2","Tissue RNA - lung [nTPM]":"87.0","Tissue RNA - lymph node [nTPM]":"62.4","Tissue RNA - medulla oblongata [nTPM]":"82.7","Tissue RNA - midbrain [nTPM]":"78.9","Tissue RNA - ovary [nTPM]":"36.6","Tissue RNA - pancreas [nTPM]":"68.2","Tissue RNA - parathyroid gland [nTPM]":"38.9","Tissue RNA - pituitary gland [nTPM]":"41.9","Tissue RNA - placenta [nTPM]":"51.3","Tissue RNA - pons [nTPM]":"79.8","Tissue RNA - prostate [nTPM]":"47.4","Tissue RNA - rectum [nTPM]":"83.9","Tissue RNA - retina [nTPM]":"30.7","Tissue RNA - salivary gland [nTPM]":"55.0","Tissue RNA - seminal vesicle [nTPM]":"55.7","Tissue RNA - skeletal muscle [nTPM]":"108.1","Tissue RNA - skin 1 [nTPM]":"92.8","Tissue RNA - small intestine [nTPM]":"99.6","Tissue RNA - smooth muscle [nTPM]":"35.1","Tissue RNA - spinal cord [nTPM]":"60.3","Tissue RNA - spleen [nTPM]":"81.0","Tissue RNA - stomach 1 [nTPM]":"98.6","Tissue RNA - testis [nTPM]":"55.1","Tissue RNA - thalamus [nTPM]":"72.9","Tissue RNA - thymus [nTPM]":"58.6","Tissue RNA - thyroid gland [nTPM]":"47.6","Tissue RNA - tongue [nTPM]":"82.8","Tissue RNA - tonsil [nTPM]":"65.4","Tissue RNA - urinary bladder [nTPM]":"64.6","Tissue RNA - vagina [nTPM]":"54.5","Tissue RNA - white matter [nTPM]":"101.6","Cell RNA - A-431 [nTPM]":"116.4","Cell RNA - A549 [nTPM]":"92.8","Cell RNA - AF22 [nTPM]":"67.6","Cell RNA - AN3-CA [nTPM]":"54.6","Cell RNA - ASC diff [nTPM]":"67.6","Cell RNA - ASC TERT1 [nTPM]":"65.4","Cell RNA - BEWO [nTPM]":"86.5","Cell RNA - BJ [nTPM]":"75.1","Cell RNA - BJ hTERT+ [nTPM]":"70.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"108.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"91.7","Cell RNA - CACO-2 [nTPM]":"94.2","Cell RNA - CAPAN-2 [nTPM]":"74.7","Cell RNA - Daudi [nTPM]":"83.2","Cell RNA - EFO-21 [nTPM]":"132.2","Cell RNA - fHDF\/TERT166 [nTPM]":"81.5","Cell RNA - GAMG [nTPM]":"52.5","Cell RNA - HaCaT [nTPM]":"99.4","Cell RNA - HAP1 [nTPM]":"92.6","Cell RNA - HBEC3-KT [nTPM]":"82.1","Cell RNA - HBF TERT88 [nTPM]":"90.8","Cell RNA - HDLM-2 [nTPM]":"103.1","Cell RNA - HEK 293 [nTPM]":"72.4","Cell RNA - HEL [nTPM]":"160.1","Cell RNA - HeLa [nTPM]":"81.7","Cell RNA - Hep G2 [nTPM]":"107.1","Cell RNA - HHSteC [nTPM]":"82.9","Cell RNA - HL-60 [nTPM]":"87.8","Cell RNA - HMC-1 [nTPM]":"146.5","Cell RNA - HSkMC [nTPM]":"67.8","Cell RNA - hTCEpi [nTPM]":"62.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"83.5","Cell RNA - hTERT-HME1 [nTPM]":"77.9","Cell RNA - hTERT-RPE1 [nTPM]":"66.2","Cell RNA - HUVEC TERT2 [nTPM]":"107.3","Cell RNA - JURKAT [nTPM]":"84.9","Cell RNA - K-562 [nTPM]":"131.5","Cell RNA - Karpas-707 [nTPM]":"139.1","Cell RNA - LHCN-M2 [nTPM]":"68.0","Cell RNA - MCF7 [nTPM]":"140.1","Cell RNA - MOLT-4 [nTPM]":"126.3","Cell RNA - NB-4 [nTPM]":"85.7","Cell RNA - NTERA-2 [nTPM]":"76.6","Cell RNA - OE19 [nTPM]":"138.3","Cell RNA - PC-3 [nTPM]":"109.7","Cell RNA - REH [nTPM]":"125.6","Cell RNA - RH-30 [nTPM]":"72.6","Cell RNA - RPMI-8226 [nTPM]":"95.7","Cell RNA - RPTEC TERT1 [nTPM]":"71.3","Cell RNA - RT4 [nTPM]":"171.1","Cell RNA - SCLC-21H [nTPM]":"97.1","Cell RNA - SH-SY5Y [nTPM]":"63.8","Cell RNA - SiHa [nTPM]":"86.6","Cell RNA - SK-BR-3 [nTPM]":"73.6","Cell RNA - SK-MEL-30 [nTPM]":"54.2","Cell RNA - SuSa [nTPM]":"74.9","Cell RNA - T-47d [nTPM]":"58.8","Cell RNA - THP-1 [nTPM]":"106.2","Cell RNA - TIME [nTPM]":"99.6","Cell RNA - U-138 MG [nTPM]":"120.7","Cell RNA - U-2 OS [nTPM]":"40.5","Cell RNA - U-2197 [nTPM]":"172.0","Cell RNA - U-251 MG [nTPM]":"102.7","Cell RNA - U-266\/70 [nTPM]":"112.7","Cell RNA - U-266\/84 [nTPM]":"127.3","Cell RNA - U-698 [nTPM]":"77.9","Cell RNA - U-87 MG [nTPM]":"89.9","Cell RNA - U-937 [nTPM]":"134.0","Cell RNA - WM-115 [nTPM]":"61.0","Blood RNA - basophil [nTPM]":"3.5","Blood RNA - classical monocyte [nTPM]":"3.5","Blood RNA - eosinophil [nTPM]":"7.0","Blood RNA - gdT-cell [nTPM]":"4.0","Blood RNA - intermediate monocyte [nTPM]":"6.2","Blood RNA - MAIT T-cell [nTPM]":"3.8","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"3.0","Blood RNA - memory CD8 T-cell [nTPM]":"4.4","Blood RNA - myeloid DC [nTPM]":"4.2","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"3.0","Blood RNA - neutrophil [nTPM]":"6.5","Blood RNA - NK-cell [nTPM]":"8.9","Blood RNA - non-classical monocyte [nTPM]":"8.4","Blood RNA - plasmacytoid DC [nTPM]":"8.4","Blood RNA - T-reg [nTPM]":"3.8","Blood RNA - total PBMC [nTPM]":"4.1","Brain RNA - amygdala [nTPM]":"50.5","Brain RNA - basal ganglia [nTPM]":"77.8","Brain RNA - cerebellum [nTPM]":"74.1","Brain RNA - cerebral cortex [nTPM]":"64.1","Brain RNA - hippocampal formation [nTPM]":"52.3","Brain RNA - hypothalamus [nTPM]":"57.4","Brain RNA - medulla oblongata [nTPM]":"82.7","Brain RNA - midbrain [nTPM]":"78.9","Brain RNA - pons [nTPM]":"79.8","Brain RNA - spinal cord [nTPM]":"60.3","Brain RNA - thalamus [nTPM]":"72.9","Brain RNA - white matter [nTPM]":"101.6","Single Cell Type RNA - Adipocytes [nTPM]":"37.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"22.3","Single Cell Type RNA - Astrocytes [nTPM]":"24.8","Single Cell Type RNA - B-cells [nTPM]":"48.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"23.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.2","Single Cell Type RNA - Bipolar cells [nTPM]":"28.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"30.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"25.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"51.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.7","Single Cell Type RNA - dendritic cells [nTPM]":"57.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"242.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"50.9","Single Cell Type RNA - Ductal cells [nTPM]":"35.2","Single Cell Type RNA - Early spermatids [nTPM]":"48.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"32.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.9","Single Cell Type RNA - Endothelial cells [nTPM]":"33.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.6","Single Cell Type RNA - Erythroid cells [nTPM]":"38.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"29.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"32.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"106.9","Single Cell Type RNA - Fibroblasts [nTPM]":"19.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"168.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"39.7","Single Cell Type RNA - granulocytes [nTPM]":"19.0","Single Cell Type RNA - Granulosa cells [nTPM]":"36.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.3","Single Cell Type RNA - Hepatocytes [nTPM]":"22.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"49.1","Single Cell Type RNA - Horizontal cells [nTPM]":"43.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"31.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"106.9","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"28.0","Single Cell Type RNA - Langerhans cells [nTPM]":"39.6","Single Cell Type RNA - Late spermatids [nTPM]":"98.0","Single Cell Type RNA - Leydig cells [nTPM]":"16.8","Single Cell Type RNA - Macrophages [nTPM]":"55.2","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"60.9","Single Cell Type RNA - monocytes [nTPM]":"43.4","Single Cell Type RNA - Muller glia cells [nTPM]":"17.2","Single Cell Type RNA - NK-cells [nTPM]":"39.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"23.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"90.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"45.2","Single Cell Type RNA - Paneth cells [nTPM]":"177.3","Single Cell Type RNA - Peritubular cells [nTPM]":"27.8","Single Cell Type RNA - Plasma cells [nTPM]":"92.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"90.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"38.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"26.3","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.6","Single Cell Type RNA - Spermatocytes [nTPM]":"15.0","Single Cell Type RNA - Spermatogonia [nTPM]":"12.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"31.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"31.7","Single Cell Type RNA - T-cells [nTPM]":"46.4","Single Cell Type RNA - Theca cells [nTPM]":"40.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"82.5","Single Cell Type RNA - Urothelial cells [nTPM]":"22.8"},{"Gene":"DNMT3A","Gene synonym":[],"Ensembl":"ENSG00000119772","Gene description":"DNA methyltransferase 3 alpha","Uniprot":["Q9Y6K1"],"Chromosome":"2","Position":"25227855-25342590","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transcription factors"],"Biological process":null,"Molecular function":["Chromatin regulator","DNA-binding","Methyltransferase","Repressor","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Dwarfism","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"127.2","Horizontal cells":"95.9","Rod photoreceptor cells":"143.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"NTERA-2":"59.6","REH":"59.5","SH-SY5Y":"71.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009469","HPA026588"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB009469":"AB_2093990","HPA026588":"AB_1847812"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.55e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.58e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.18e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.49e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.6","Tissue RNA - adrenal gland [nTPM]":"9.0","Tissue RNA - amygdala [nTPM]":"8.9","Tissue RNA - appendix [nTPM]":"9.8","Tissue RNA - basal ganglia [nTPM]":"12.6","Tissue RNA - bone marrow [nTPM]":"8.7","Tissue RNA - breast [nTPM]":"6.2","Tissue RNA - cerebellum [nTPM]":"9.3","Tissue RNA - cerebral cortex [nTPM]":"10.7","Tissue RNA - cervix [nTPM]":"9.1","Tissue RNA - choroid plexus [nTPM]":"2.4","Tissue RNA - colon [nTPM]":"11.3","Tissue RNA - duodenum [nTPM]":"6.7","Tissue RNA - endometrium 1 [nTPM]":"9.3","Tissue RNA - epididymis [nTPM]":"8.7","Tissue RNA - esophagus [nTPM]":"6.0","Tissue RNA - fallopian tube [nTPM]":"7.5","Tissue RNA - gallbladder [nTPM]":"6.3","Tissue RNA - heart muscle [nTPM]":"5.9","Tissue RNA - hippocampal formation [nTPM]":"8.8","Tissue RNA - hypothalamus [nTPM]":"7.9","Tissue RNA - kidney [nTPM]":"11.3","Tissue RNA - liver [nTPM]":"5.3","Tissue RNA - lung [nTPM]":"7.3","Tissue RNA - lymph node [nTPM]":"11.1","Tissue RNA - medulla oblongata [nTPM]":"9.0","Tissue RNA - midbrain [nTPM]":"7.6","Tissue RNA - ovary [nTPM]":"13.0","Tissue RNA - pancreas [nTPM]":"8.3","Tissue RNA - parathyroid gland [nTPM]":"4.2","Tissue RNA - pituitary gland [nTPM]":"11.5","Tissue RNA - placenta [nTPM]":"15.7","Tissue RNA - pons [nTPM]":"8.6","Tissue RNA - prostate [nTPM]":"7.2","Tissue RNA - rectum [nTPM]":"6.6","Tissue RNA - retina [nTPM]":"15.4","Tissue RNA - salivary gland [nTPM]":"6.2","Tissue RNA - seminal vesicle [nTPM]":"5.9","Tissue RNA - skeletal muscle [nTPM]":"21.0","Tissue RNA - skin 1 [nTPM]":"4.9","Tissue RNA - small intestine [nTPM]":"8.9","Tissue RNA - smooth muscle [nTPM]":"7.1","Tissue RNA - spinal cord [nTPM]":"5.2","Tissue RNA - spleen [nTPM]":"13.4","Tissue RNA - stomach 1 [nTPM]":"8.5","Tissue RNA - testis [nTPM]":"5.2","Tissue RNA - thalamus [nTPM]":"9.4","Tissue RNA - thymus [nTPM]":"20.6","Tissue RNA - thyroid gland [nTPM]":"6.9","Tissue RNA - tongue [nTPM]":"10.2","Tissue RNA - tonsil [nTPM]":"9.0","Tissue RNA - urinary bladder [nTPM]":"7.3","Tissue RNA - vagina [nTPM]":"6.2","Tissue RNA - white matter [nTPM]":"11.3","Cell RNA - A-431 [nTPM]":"1.6","Cell RNA - A549 [nTPM]":"8.1","Cell RNA - AF22 [nTPM]":"34.6","Cell RNA - AN3-CA [nTPM]":"8.3","Cell RNA - ASC diff [nTPM]":"3.8","Cell RNA - ASC TERT1 [nTPM]":"2.7","Cell RNA - BEWO [nTPM]":"45.2","Cell RNA - BJ [nTPM]":"1.9","Cell RNA - BJ hTERT+ [nTPM]":"2.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.8","Cell RNA - CACO-2 [nTPM]":"21.1","Cell RNA - CAPAN-2 [nTPM]":"13.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"4.7","Cell RNA - fHDF\/TERT166 [nTPM]":"4.7","Cell RNA - GAMG [nTPM]":"3.5","Cell RNA - HaCaT [nTPM]":"2.2","Cell RNA - HAP1 [nTPM]":"3.8","Cell RNA - HBEC3-KT [nTPM]":"5.2","Cell RNA - HBF TERT88 [nTPM]":"2.8","Cell RNA - HDLM-2 [nTPM]":"5.7","Cell RNA - HEK 293 [nTPM]":"4.3","Cell RNA - HEL [nTPM]":"14.7","Cell RNA - HeLa [nTPM]":"12.8","Cell RNA - Hep G2 [nTPM]":"25.4","Cell RNA - HHSteC [nTPM]":"8.8","Cell RNA - HL-60 [nTPM]":"2.9","Cell RNA - HMC-1 [nTPM]":"7.6","Cell RNA - HSkMC [nTPM]":"8.2","Cell RNA - hTCEpi [nTPM]":"2.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.0","Cell RNA - hTERT-HME1 [nTPM]":"2.2","Cell RNA - hTERT-RPE1 [nTPM]":"9.1","Cell RNA - HUVEC TERT2 [nTPM]":"19.5","Cell RNA - JURKAT [nTPM]":"34.0","Cell RNA - K-562 [nTPM]":"18.0","Cell RNA - Karpas-707 [nTPM]":"2.9","Cell RNA - LHCN-M2 [nTPM]":"3.5","Cell RNA - MCF7 [nTPM]":"20.6","Cell RNA - MOLT-4 [nTPM]":"33.7","Cell RNA - NB-4 [nTPM]":"36.5","Cell RNA - NTERA-2 [nTPM]":"59.6","Cell RNA - OE19 [nTPM]":"14.3","Cell RNA - PC-3 [nTPM]":"4.2","Cell RNA - REH [nTPM]":"59.5","Cell RNA - RH-30 [nTPM]":"32.5","Cell RNA - RPMI-8226 [nTPM]":"3.8","Cell RNA - RPTEC TERT1 [nTPM]":"2.9","Cell RNA - RT4 [nTPM]":"3.4","Cell RNA - SCLC-21H [nTPM]":"18.6","Cell RNA - SH-SY5Y [nTPM]":"71.5","Cell RNA - SiHa [nTPM]":"2.7","Cell RNA - SK-BR-3 [nTPM]":"19.6","Cell RNA - SK-MEL-30 [nTPM]":"6.2","Cell RNA - SuSa [nTPM]":"29.5","Cell RNA - T-47d [nTPM]":"2.1","Cell RNA - THP-1 [nTPM]":"16.2","Cell RNA - TIME [nTPM]":"6.8","Cell RNA - U-138 MG [nTPM]":"5.4","Cell RNA - U-2 OS [nTPM]":"4.7","Cell RNA - U-2197 [nTPM]":"1.0","Cell RNA - U-251 MG [nTPM]":"2.5","Cell RNA - U-266\/70 [nTPM]":"5.6","Cell RNA - U-266\/84 [nTPM]":"5.1","Cell RNA - U-698 [nTPM]":"19.6","Cell RNA - U-87 MG [nTPM]":"2.2","Cell RNA - U-937 [nTPM]":"8.4","Cell RNA - WM-115 [nTPM]":"5.5","Blood RNA - basophil [nTPM]":"2.8","Blood RNA - classical monocyte [nTPM]":"1.0","Blood RNA - eosinophil [nTPM]":"2.1","Blood RNA - gdT-cell [nTPM]":"2.7","Blood RNA - intermediate monocyte [nTPM]":"1.7","Blood RNA - MAIT T-cell [nTPM]":"4.0","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"1.7","Blood RNA - memory CD8 T-cell [nTPM]":"2.4","Blood RNA - myeloid DC [nTPM]":"1.3","Blood RNA - naive B-cell [nTPM]":"1.6","Blood RNA - naive CD4 T-cell [nTPM]":"4.6","Blood RNA - naive CD8 T-cell [nTPM]":"3.9","Blood RNA - neutrophil [nTPM]":"2.5","Blood RNA - NK-cell [nTPM]":"5.5","Blood RNA - non-classical monocyte [nTPM]":"2.7","Blood RNA - plasmacytoid DC [nTPM]":"2.3","Blood RNA - T-reg [nTPM]":"1.9","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"8.9","Brain RNA - basal ganglia [nTPM]":"12.6","Brain RNA - cerebellum [nTPM]":"9.3","Brain RNA - cerebral cortex [nTPM]":"10.7","Brain RNA - hippocampal formation [nTPM]":"8.8","Brain RNA - hypothalamus [nTPM]":"7.9","Brain RNA - medulla oblongata [nTPM]":"9.0","Brain RNA - midbrain [nTPM]":"7.6","Brain RNA - pons [nTPM]":"8.6","Brain RNA - spinal cord [nTPM]":"5.2","Brain RNA - thalamus [nTPM]":"9.4","Brain RNA - white matter [nTPM]":"11.3","Single Cell Type RNA - Adipocytes [nTPM]":"18.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.1","Single Cell Type RNA - Astrocytes [nTPM]":"28.1","Single Cell Type RNA - B-cells [nTPM]":"11.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"73.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"9.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"127.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"40.6","Single Cell Type RNA - dendritic cells [nTPM]":"15.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"16.9","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.1","Single Cell Type RNA - Endothelial cells [nTPM]":"20.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"15.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"49.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.7","Single Cell Type RNA - Fibroblasts [nTPM]":"16.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.7","Single Cell Type RNA - granulocytes [nTPM]":"37.4","Single Cell Type RNA - Granulosa cells [nTPM]":"37.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"6.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.2","Single Cell Type RNA - Horizontal cells [nTPM]":"95.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"43.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.4","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"14.2","Single Cell Type RNA - Langerhans cells [nTPM]":"3.9","Single Cell Type RNA - Late spermatids [nTPM]":"1.9","Single Cell Type RNA - Leydig cells [nTPM]":"19.3","Single Cell Type RNA - Macrophages [nTPM]":"13.7","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"38.4","Single Cell Type RNA - monocytes [nTPM]":"7.4","Single Cell Type RNA - Muller glia cells [nTPM]":"20.6","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"36.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"63.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.3","Single Cell Type RNA - Paneth cells [nTPM]":"9.4","Single Cell Type RNA - Peritubular cells [nTPM]":"15.4","Single Cell Type RNA - Plasma cells [nTPM]":"9.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"143.5","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.3","Single Cell Type RNA - Spermatocytes [nTPM]":"2.8","Single Cell Type RNA - Spermatogonia [nTPM]":"14.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"32.2","Single Cell Type RNA - T-cells [nTPM]":"19.6","Single Cell Type RNA - Theca cells [nTPM]":"26.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.1","Single Cell Type RNA - Urothelial cells [nTPM]":"10.2"},{"Gene":"DNMT3B","Gene synonym":[],"Ensembl":"ENSG00000088305","Gene description":"DNA methyltransferase 3 beta","Uniprot":["Q9UBC3"],"Chromosome":"20","Position":"32762385-32809356","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transcription factors"],"Biological process":null,"Molecular function":["Activator","DNA-binding","Methyltransferase","Repressor","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"5.3","Extravillous trophoblasts":"5.2","Horizontal cells":"5.0","Inhibitory neurons":"6.8","Sertoli cells":"6.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"25","RNA cancer specific FPKM":{"testis cancer":"111.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"245.7","CACO-2":"95.8","HEL":"100.7","K-562":"98.6","NTERA-2":"333.9","SuSa":"174.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001595","HPA001803","CAB069896"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB069896":"AB_2094115","HPA001595":"AB_1847814","HPA001803":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.04e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.87e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.8","Tissue RNA - adrenal gland [nTPM]":"0.6","Tissue RNA - amygdala [nTPM]":"1.2","Tissue RNA - appendix [nTPM]":"0.8","Tissue RNA - basal ganglia [nTPM]":"1.5","Tissue RNA - bone marrow [nTPM]":"3.6","Tissue RNA - breast [nTPM]":"1.3","Tissue RNA - cerebellum [nTPM]":"2.4","Tissue RNA - cerebral cortex [nTPM]":"1.6","Tissue RNA - cervix [nTPM]":"1.3","Tissue RNA - choroid plexus [nTPM]":"1.0","Tissue RNA - colon [nTPM]":"0.7","Tissue RNA - duodenum [nTPM]":"0.8","Tissue RNA - endometrium 1 [nTPM]":"1.0","Tissue RNA - epididymis [nTPM]":"3.1","Tissue RNA - esophagus [nTPM]":"0.8","Tissue RNA - fallopian tube [nTPM]":"0.7","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"1.0","Tissue RNA - hippocampal formation [nTPM]":"1.2","Tissue RNA - hypothalamus [nTPM]":"1.6","Tissue RNA - kidney [nTPM]":"1.7","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"0.7","Tissue RNA - lymph node [nTPM]":"0.9","Tissue RNA - medulla oblongata [nTPM]":"1.4","Tissue RNA - midbrain [nTPM]":"1.3","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"6.0","Tissue RNA - parathyroid gland [nTPM]":"1.1","Tissue RNA - pituitary gland [nTPM]":"0.6","Tissue RNA - placenta [nTPM]":"2.0","Tissue RNA - pons [nTPM]":"1.3","Tissue RNA - prostate [nTPM]":"0.8","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"3.0","Tissue RNA - salivary gland [nTPM]":"1.2","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"3.8","Tissue RNA - small intestine [nTPM]":"0.8","Tissue RNA - smooth muscle [nTPM]":"0.9","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"1.0","Tissue RNA - stomach 1 [nTPM]":"0.9","Tissue RNA - testis [nTPM]":"5.8","Tissue RNA - thalamus [nTPM]":"1.4","Tissue RNA - thymus [nTPM]":"3.7","Tissue RNA - thyroid gland [nTPM]":"1.7","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.9","Tissue RNA - urinary bladder [nTPM]":"1.3","Tissue RNA - vagina [nTPM]":"1.1","Tissue RNA - white matter [nTPM]":"1.4","Cell RNA - A-431 [nTPM]":"3.9","Cell RNA - A549 [nTPM]":"5.3","Cell RNA - AF22 [nTPM]":"27.0","Cell RNA - AN3-CA [nTPM]":"6.2","Cell RNA - ASC diff [nTPM]":"0.5","Cell RNA - ASC TERT1 [nTPM]":"2.1","Cell RNA - BEWO [nTPM]":"245.7","Cell RNA - BJ [nTPM]":"3.5","Cell RNA - BJ hTERT+ [nTPM]":"2.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.8","Cell RNA - CACO-2 [nTPM]":"95.8","Cell RNA - CAPAN-2 [nTPM]":"4.3","Cell RNA - Daudi [nTPM]":"10.0","Cell RNA - EFO-21 [nTPM]":"9.7","Cell RNA - fHDF\/TERT166 [nTPM]":"1.7","Cell RNA - GAMG [nTPM]":"4.3","Cell RNA - HaCaT [nTPM]":"2.2","Cell RNA - HAP1 [nTPM]":"17.6","Cell RNA - HBEC3-KT [nTPM]":"1.7","Cell RNA - HBF TERT88 [nTPM]":"3.0","Cell RNA - HDLM-2 [nTPM]":"1.2","Cell RNA - HEK 293 [nTPM]":"14.0","Cell RNA - HEL [nTPM]":"100.7","Cell RNA - HeLa [nTPM]":"3.3","Cell RNA - Hep G2 [nTPM]":"18.5","Cell RNA - HHSteC [nTPM]":"0.9","Cell RNA - HL-60 [nTPM]":"4.6","Cell RNA - HMC-1 [nTPM]":"9.7","Cell RNA - HSkMC [nTPM]":"2.3","Cell RNA - hTCEpi [nTPM]":"1.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.5","Cell RNA - hTERT-HME1 [nTPM]":"1.1","Cell RNA - hTERT-RPE1 [nTPM]":"1.8","Cell RNA - HUVEC TERT2 [nTPM]":"6.6","Cell RNA - JURKAT [nTPM]":"6.2","Cell RNA - K-562 [nTPM]":"98.6","Cell RNA - Karpas-707 [nTPM]":"2.7","Cell RNA - LHCN-M2 [nTPM]":"1.4","Cell RNA - MCF7 [nTPM]":"15.7","Cell RNA - MOLT-4 [nTPM]":"15.6","Cell RNA - NB-4 [nTPM]":"86.1","Cell RNA - NTERA-2 [nTPM]":"333.9","Cell RNA - OE19 [nTPM]":"8.8","Cell RNA - PC-3 [nTPM]":"3.2","Cell RNA - REH [nTPM]":"15.4","Cell RNA - RH-30 [nTPM]":"4.5","Cell RNA - RPMI-8226 [nTPM]":"2.3","Cell RNA - RPTEC TERT1 [nTPM]":"9.1","Cell RNA - RT4 [nTPM]":"4.2","Cell RNA - SCLC-21H [nTPM]":"8.6","Cell RNA - SH-SY5Y [nTPM]":"5.7","Cell RNA - SiHa [nTPM]":"5.9","Cell RNA - SK-BR-3 [nTPM]":"8.5","Cell RNA - SK-MEL-30 [nTPM]":"2.5","Cell RNA - SuSa [nTPM]":"174.4","Cell RNA - T-47d [nTPM]":"5.8","Cell RNA - THP-1 [nTPM]":"5.5","Cell RNA - TIME [nTPM]":"1.6","Cell RNA - U-138 MG [nTPM]":"5.5","Cell RNA - U-2 OS [nTPM]":"12.3","Cell RNA - U-2197 [nTPM]":"2.8","Cell RNA - U-251 MG [nTPM]":"2.6","Cell RNA - U-266\/70 [nTPM]":"5.9","Cell RNA - U-266\/84 [nTPM]":"2.8","Cell RNA - U-698 [nTPM]":"3.8","Cell RNA - U-87 MG [nTPM]":"2.6","Cell RNA - U-937 [nTPM]":"27.4","Cell RNA - WM-115 [nTPM]":"2.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.2","Brain RNA - basal ganglia [nTPM]":"1.5","Brain RNA - cerebellum [nTPM]":"2.4","Brain RNA - cerebral cortex [nTPM]":"1.6","Brain RNA - hippocampal formation [nTPM]":"1.2","Brain RNA - hypothalamus [nTPM]":"1.6","Brain RNA - medulla oblongata [nTPM]":"1.4","Brain RNA - midbrain [nTPM]":"1.3","Brain RNA - pons [nTPM]":"1.3","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"1.4","Brain RNA - white matter [nTPM]":"1.4","Single Cell Type RNA - Adipocytes [nTPM]":"1.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.5","Single Cell Type RNA - Astrocytes [nTPM]":"3.9","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"2.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.9","Single Cell Type RNA - Endothelial cells [nTPM]":"1.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"4.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.2","Single Cell Type RNA - Fibroblasts [nTPM]":"1.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.8","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"1.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"2.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.8","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"DOLK","Gene synonym":["DK1","KIAA1094","TMEM15"],"Ensembl":"ENSG00000175283","Gene description":"Dolichol kinase","Uniprot":["Q9UPQ8"],"Chromosome":"9","Position":"128945530-128947603","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"33.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066767","HPA068706"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA066767":"AB_2732751","HPA068706":"AB_2732118"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.90e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.53e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.88e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-3"},"Tissue RNA - adipose tissue [nTPM]":"9.6","Tissue RNA - adrenal gland [nTPM]":"14.3","Tissue RNA - amygdala [nTPM]":"6.6","Tissue RNA - appendix [nTPM]":"6.3","Tissue RNA - basal ganglia [nTPM]":"6.3","Tissue RNA - bone marrow [nTPM]":"1.5","Tissue RNA - breast [nTPM]":"7.8","Tissue RNA - cerebellum [nTPM]":"6.7","Tissue RNA - cerebral cortex [nTPM]":"6.7","Tissue RNA - cervix [nTPM]":"7.4","Tissue RNA - choroid plexus [nTPM]":"8.6","Tissue RNA - colon [nTPM]":"7.5","Tissue RNA - duodenum [nTPM]":"7.6","Tissue RNA - endometrium 1 [nTPM]":"9.3","Tissue RNA - epididymis [nTPM]":"13.5","Tissue RNA - esophagus [nTPM]":"8.6","Tissue RNA - fallopian tube [nTPM]":"8.9","Tissue RNA - gallbladder [nTPM]":"7.9","Tissue RNA - heart muscle [nTPM]":"10.5","Tissue RNA - hippocampal formation [nTPM]":"6.5","Tissue RNA - hypothalamus [nTPM]":"7.1","Tissue RNA - kidney [nTPM]":"9.1","Tissue RNA - liver [nTPM]":"10.5","Tissue RNA - lung [nTPM]":"9.1","Tissue RNA - lymph node [nTPM]":"6.8","Tissue RNA - medulla oblongata [nTPM]":"6.9","Tissue RNA - midbrain [nTPM]":"7.6","Tissue RNA - ovary [nTPM]":"6.7","Tissue RNA - pancreas [nTPM]":"14.5","Tissue RNA - parathyroid gland [nTPM]":"16.8","Tissue RNA - pituitary gland [nTPM]":"5.9","Tissue RNA - placenta [nTPM]":"9.3","Tissue RNA - pons [nTPM]":"7.3","Tissue RNA - prostate [nTPM]":"10.0","Tissue RNA - rectum [nTPM]":"6.6","Tissue RNA - retina [nTPM]":"4.4","Tissue RNA - salivary gland [nTPM]":"12.0","Tissue RNA - seminal vesicle [nTPM]":"10.0","Tissue RNA - skeletal muscle [nTPM]":"6.7","Tissue RNA - skin 1 [nTPM]":"9.9","Tissue RNA - small intestine [nTPM]":"7.5","Tissue RNA - smooth muscle [nTPM]":"9.4","Tissue RNA - spinal cord [nTPM]":"6.5","Tissue RNA - spleen [nTPM]":"8.0","Tissue RNA - stomach 1 [nTPM]":"10.6","Tissue RNA - testis [nTPM]":"14.5","Tissue RNA - thalamus [nTPM]":"7.6","Tissue RNA - thymus [nTPM]":"5.1","Tissue RNA - thyroid gland [nTPM]":"7.8","Tissue RNA - tongue [nTPM]":"7.1","Tissue RNA - tonsil [nTPM]":"6.6","Tissue RNA - urinary bladder [nTPM]":"8.6","Tissue RNA - vagina [nTPM]":"5.9","Tissue RNA - white matter [nTPM]":"6.8","Cell RNA - A-431 [nTPM]":"11.7","Cell RNA - A549 [nTPM]":"42.5","Cell RNA - AF22 [nTPM]":"14.8","Cell RNA - AN3-CA [nTPM]":"22.0","Cell RNA - ASC diff [nTPM]":"42.6","Cell RNA - ASC TERT1 [nTPM]":"22.2","Cell RNA - BEWO [nTPM]":"20.0","Cell RNA - BJ [nTPM]":"23.7","Cell RNA - BJ hTERT+ [nTPM]":"38.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"28.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.0","Cell RNA - CACO-2 [nTPM]":"33.7","Cell RNA - CAPAN-2 [nTPM]":"17.9","Cell RNA - Daudi [nTPM]":"6.4","Cell RNA - EFO-21 [nTPM]":"12.3","Cell RNA - fHDF\/TERT166 [nTPM]":"34.6","Cell RNA - GAMG [nTPM]":"40.3","Cell RNA - HaCaT [nTPM]":"80.3","Cell RNA - HAP1 [nTPM]":"20.3","Cell RNA - HBEC3-KT [nTPM]":"29.6","Cell RNA - HBF TERT88 [nTPM]":"14.7","Cell RNA - HDLM-2 [nTPM]":"10.7","Cell RNA - HEK 293 [nTPM]":"17.8","Cell RNA - HEL [nTPM]":"8.0","Cell RNA - HeLa [nTPM]":"27.4","Cell RNA - Hep G2 [nTPM]":"24.5","Cell RNA - HHSteC [nTPM]":"43.0","Cell RNA - HL-60 [nTPM]":"8.8","Cell RNA - HMC-1 [nTPM]":"13.5","Cell RNA - HSkMC [nTPM]":"31.1","Cell RNA - hTCEpi [nTPM]":"27.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"30.8","Cell RNA - hTERT-HME1 [nTPM]":"16.8","Cell RNA - hTERT-RPE1 [nTPM]":"16.7","Cell RNA - HUVEC TERT2 [nTPM]":"28.1","Cell RNA - JURKAT [nTPM]":"9.1","Cell RNA - K-562 [nTPM]":"19.7","Cell RNA - Karpas-707 [nTPM]":"10.0","Cell RNA - LHCN-M2 [nTPM]":"31.3","Cell RNA - MCF7 [nTPM]":"56.9","Cell RNA - MOLT-4 [nTPM]":"7.3","Cell RNA - NB-4 [nTPM]":"7.3","Cell RNA - NTERA-2 [nTPM]":"19.0","Cell RNA - OE19 [nTPM]":"33.0","Cell RNA - PC-3 [nTPM]":"26.0","Cell RNA - REH [nTPM]":"7.2","Cell RNA - RH-30 [nTPM]":"19.5","Cell RNA - RPMI-8226 [nTPM]":"25.1","Cell RNA - RPTEC TERT1 [nTPM]":"25.7","Cell RNA - RT4 [nTPM]":"17.3","Cell RNA - SCLC-21H [nTPM]":"13.5","Cell RNA - SH-SY5Y [nTPM]":"15.1","Cell RNA - SiHa [nTPM]":"31.4","Cell RNA - SK-BR-3 [nTPM]":"25.6","Cell RNA - SK-MEL-30 [nTPM]":"14.1","Cell RNA - SuSa [nTPM]":"13.7","Cell RNA - T-47d [nTPM]":"44.8","Cell RNA - THP-1 [nTPM]":"11.4","Cell RNA - TIME [nTPM]":"23.6","Cell RNA - U-138 MG [nTPM]":"25.6","Cell RNA - U-2 OS [nTPM]":"9.2","Cell RNA - U-2197 [nTPM]":"32.5","Cell RNA - U-251 MG [nTPM]":"19.8","Cell RNA - U-266\/70 [nTPM]":"9.4","Cell RNA - U-266\/84 [nTPM]":"25.0","Cell RNA - U-698 [nTPM]":"6.4","Cell RNA - U-87 MG [nTPM]":"24.2","Cell RNA - U-937 [nTPM]":"8.0","Cell RNA - WM-115 [nTPM]":"19.9","Blood RNA - basophil [nTPM]":"2.7","Blood RNA - classical monocyte [nTPM]":"15.4","Blood RNA - eosinophil [nTPM]":"6.9","Blood RNA - gdT-cell [nTPM]":"11.2","Blood RNA - intermediate monocyte [nTPM]":"15.3","Blood RNA - MAIT T-cell [nTPM]":"10.1","Blood RNA - memory B-cell [nTPM]":"11.8","Blood RNA - memory CD4 T-cell [nTPM]":"9.9","Blood RNA - memory CD8 T-cell [nTPM]":"12.3","Blood RNA - myeloid DC [nTPM]":"16.6","Blood RNA - naive B-cell [nTPM]":"12.5","Blood RNA - naive CD4 T-cell [nTPM]":"12.8","Blood RNA - naive CD8 T-cell [nTPM]":"13.2","Blood RNA - neutrophil [nTPM]":"2.2","Blood RNA - NK-cell [nTPM]":"13.0","Blood RNA - non-classical monocyte [nTPM]":"21.2","Blood RNA - plasmacytoid DC [nTPM]":"9.3","Blood RNA - T-reg [nTPM]":"16.8","Blood RNA - total PBMC [nTPM]":"10.5","Brain RNA - amygdala [nTPM]":"6.6","Brain RNA - basal ganglia [nTPM]":"6.3","Brain RNA - cerebellum [nTPM]":"6.7","Brain RNA - cerebral cortex [nTPM]":"6.7","Brain RNA - hippocampal formation [nTPM]":"6.5","Brain RNA - hypothalamus [nTPM]":"7.1","Brain RNA - medulla oblongata [nTPM]":"6.9","Brain RNA - midbrain [nTPM]":"7.6","Brain RNA - pons [nTPM]":"7.3","Brain RNA - spinal cord [nTPM]":"6.5","Brain RNA - thalamus [nTPM]":"7.6","Brain RNA - white matter [nTPM]":"6.8","Single Cell Type RNA - Adipocytes [nTPM]":"8.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.1","Single Cell Type RNA - Astrocytes [nTPM]":"2.9","Single Cell Type RNA - B-cells [nTPM]":"2.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"9.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"10.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.6","Single Cell Type RNA - dendritic cells [nTPM]":"3.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"15.7","Single Cell Type RNA - Early spermatids [nTPM]":"15.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.2","Single Cell Type RNA - Endothelial cells [nTPM]":"9.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"3.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"16.4","Single Cell Type RNA - Fibroblasts [nTPM]":"8.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.6","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"7.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.1","Single Cell Type RNA - Hepatocytes [nTPM]":"9.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.5","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.5","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.2","Single Cell Type RNA - Langerhans cells [nTPM]":"2.7","Single Cell Type RNA - Late spermatids [nTPM]":"3.7","Single Cell Type RNA - Leydig cells [nTPM]":"12.2","Single Cell Type RNA - Macrophages [nTPM]":"2.9","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"2.8","Single Cell Type RNA - Muller glia cells [nTPM]":"10.7","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.1","Single Cell Type RNA - Paneth cells [nTPM]":"7.5","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.7","Single Cell Type RNA - Spermatocytes [nTPM]":"33.8","Single Cell Type RNA - Spermatogonia [nTPM]":"15.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"18.2","Single Cell Type RNA - T-cells [nTPM]":"2.3","Single Cell Type RNA - Theca cells [nTPM]":"15.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.7","Single Cell Type RNA - Urothelial cells [nTPM]":"2.1"},{"Gene":"DPAGT1","Gene synonym":["ALG7","CDG-Ij","D11S366","DGPT","DPAGT","DPAGT2","GPT"],"Ensembl":"ENSG00000172269","Gene description":"Dolichyl-phosphate N-acetylglucosaminephosphotransferase 1","Uniprot":["Q9H3H5"],"Chromosome":"11","Position":"119096503-119108331","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053878"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053878":"AB_2682288"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.03e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.3","Tissue RNA - adrenal gland [nTPM]":"14.1","Tissue RNA - amygdala [nTPM]":"13.0","Tissue RNA - appendix [nTPM]":"13.7","Tissue RNA - basal ganglia [nTPM]":"13.3","Tissue RNA - bone marrow [nTPM]":"9.1","Tissue RNA - breast [nTPM]":"14.8","Tissue RNA - cerebellum [nTPM]":"13.9","Tissue RNA - cerebral cortex [nTPM]":"22.4","Tissue RNA - cervix [nTPM]":"16.1","Tissue RNA - choroid plexus [nTPM]":"17.6","Tissue RNA - colon [nTPM]":"17.7","Tissue RNA - duodenum [nTPM]":"16.8","Tissue RNA - endometrium 1 [nTPM]":"10.2","Tissue RNA - epididymis [nTPM]":"21.8","Tissue RNA - esophagus [nTPM]":"12.4","Tissue RNA - fallopian tube [nTPM]":"17.3","Tissue RNA - gallbladder [nTPM]":"14.5","Tissue RNA - heart muscle [nTPM]":"8.6","Tissue RNA - hippocampal formation [nTPM]":"13.5","Tissue RNA - hypothalamus [nTPM]":"14.1","Tissue RNA - kidney [nTPM]":"12.8","Tissue RNA - liver [nTPM]":"21.2","Tissue RNA - lung [nTPM]":"11.4","Tissue RNA - lymph node [nTPM]":"11.5","Tissue RNA - medulla oblongata [nTPM]":"14.2","Tissue RNA - midbrain [nTPM]":"14.4","Tissue RNA - ovary [nTPM]":"9.0","Tissue RNA - pancreas [nTPM]":"27.1","Tissue RNA - parathyroid gland [nTPM]":"18.6","Tissue RNA - pituitary gland [nTPM]":"4.4","Tissue RNA - placenta [nTPM]":"15.8","Tissue RNA - pons [nTPM]":"14.2","Tissue RNA - prostate [nTPM]":"14.3","Tissue RNA - rectum [nTPM]":"20.0","Tissue RNA - retina [nTPM]":"7.4","Tissue RNA - salivary gland [nTPM]":"27.8","Tissue RNA - seminal vesicle [nTPM]":"16.3","Tissue RNA - skeletal muscle [nTPM]":"5.6","Tissue RNA - skin 1 [nTPM]":"9.0","Tissue RNA - small intestine [nTPM]":"14.9","Tissue RNA - smooth muscle [nTPM]":"17.7","Tissue RNA - spinal cord [nTPM]":"13.4","Tissue RNA - spleen [nTPM]":"9.8","Tissue RNA - stomach 1 [nTPM]":"14.4","Tissue RNA - testis [nTPM]":"4.8","Tissue RNA - thalamus [nTPM]":"14.6","Tissue RNA - thymus [nTPM]":"8.2","Tissue RNA - thyroid gland [nTPM]":"15.5","Tissue RNA - tongue [nTPM]":"8.5","Tissue RNA - tonsil [nTPM]":"14.3","Tissue RNA - urinary bladder [nTPM]":"16.8","Tissue RNA - vagina [nTPM]":"6.2","Tissue RNA - white matter [nTPM]":"14.9","Cell RNA - A-431 [nTPM]":"22.0","Cell RNA - A549 [nTPM]":"39.2","Cell RNA - AF22 [nTPM]":"22.2","Cell RNA - AN3-CA [nTPM]":"55.7","Cell RNA - ASC diff [nTPM]":"60.0","Cell RNA - ASC TERT1 [nTPM]":"37.0","Cell RNA - BEWO [nTPM]":"24.6","Cell RNA - BJ [nTPM]":"33.7","Cell RNA - BJ hTERT+ [nTPM]":"38.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"25.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"32.2","Cell RNA - CACO-2 [nTPM]":"43.4","Cell RNA - CAPAN-2 [nTPM]":"88.3","Cell RNA - Daudi [nTPM]":"41.5","Cell RNA - EFO-21 [nTPM]":"62.8","Cell RNA - fHDF\/TERT166 [nTPM]":"45.4","Cell RNA - GAMG [nTPM]":"57.7","Cell RNA - HaCaT [nTPM]":"77.1","Cell RNA - HAP1 [nTPM]":"42.0","Cell RNA - HBEC3-KT [nTPM]":"60.7","Cell RNA - HBF TERT88 [nTPM]":"31.1","Cell RNA - HDLM-2 [nTPM]":"29.4","Cell RNA - HEK 293 [nTPM]":"23.8","Cell RNA - HEL [nTPM]":"83.5","Cell RNA - HeLa [nTPM]":"14.1","Cell RNA - Hep G2 [nTPM]":"51.6","Cell RNA - HHSteC [nTPM]":"50.7","Cell RNA - HL-60 [nTPM]":"53.9","Cell RNA - HMC-1 [nTPM]":"47.4","Cell RNA - HSkMC [nTPM]":"40.3","Cell RNA - hTCEpi [nTPM]":"48.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"62.4","Cell RNA - hTERT-HME1 [nTPM]":"85.3","Cell RNA - hTERT-RPE1 [nTPM]":"29.9","Cell RNA - HUVEC TERT2 [nTPM]":"53.3","Cell RNA - JURKAT [nTPM]":"25.2","Cell RNA - K-562 [nTPM]":"51.7","Cell RNA - Karpas-707 [nTPM]":"84.1","Cell RNA - LHCN-M2 [nTPM]":"50.9","Cell RNA - MCF7 [nTPM]":"67.7","Cell RNA - MOLT-4 [nTPM]":"19.5","Cell RNA - NB-4 [nTPM]":"39.9","Cell RNA - NTERA-2 [nTPM]":"22.5","Cell RNA - OE19 [nTPM]":"148.3","Cell RNA - PC-3 [nTPM]":"49.4","Cell RNA - REH [nTPM]":"26.2","Cell RNA - RH-30 [nTPM]":"26.6","Cell RNA - RPMI-8226 [nTPM]":"61.3","Cell RNA - RPTEC TERT1 [nTPM]":"60.3","Cell RNA - RT4 [nTPM]":"44.7","Cell RNA - SCLC-21H [nTPM]":"23.0","Cell RNA - SH-SY5Y [nTPM]":"30.1","Cell RNA - SiHa [nTPM]":"30.7","Cell RNA - SK-BR-3 [nTPM]":"99.3","Cell RNA - SK-MEL-30 [nTPM]":"17.1","Cell RNA - SuSa [nTPM]":"32.3","Cell RNA - T-47d [nTPM]":"116.8","Cell RNA - THP-1 [nTPM]":"19.4","Cell RNA - TIME [nTPM]":"29.1","Cell RNA - U-138 MG [nTPM]":"57.3","Cell RNA - U-2 OS [nTPM]":"24.5","Cell RNA - U-2197 [nTPM]":"30.3","Cell RNA - U-251 MG [nTPM]":"23.7","Cell RNA - U-266\/70 [nTPM]":"19.6","Cell RNA - U-266\/84 [nTPM]":"32.2","Cell RNA - U-698 [nTPM]":"13.9","Cell RNA - U-87 MG [nTPM]":"14.3","Cell RNA - U-937 [nTPM]":"68.3","Cell RNA - WM-115 [nTPM]":"48.9","Blood RNA - basophil [nTPM]":"28.4","Blood RNA - classical monocyte [nTPM]":"35.7","Blood RNA - eosinophil [nTPM]":"4.4","Blood RNA - gdT-cell [nTPM]":"25.2","Blood RNA - intermediate monocyte [nTPM]":"35.5","Blood RNA - MAIT T-cell [nTPM]":"28.4","Blood RNA - memory B-cell [nTPM]":"24.5","Blood RNA - memory CD4 T-cell [nTPM]":"20.1","Blood RNA - memory CD8 T-cell [nTPM]":"24.8","Blood RNA - myeloid DC [nTPM]":"43.3","Blood RNA - naive B-cell [nTPM]":"25.6","Blood RNA - naive CD4 T-cell [nTPM]":"16.6","Blood RNA - naive CD8 T-cell [nTPM]":"15.8","Blood RNA - neutrophil [nTPM]":"3.0","Blood RNA - NK-cell [nTPM]":"20.7","Blood RNA - non-classical monocyte [nTPM]":"32.7","Blood RNA - plasmacytoid DC [nTPM]":"37.5","Blood RNA - T-reg [nTPM]":"19.6","Blood RNA - total PBMC [nTPM]":"20.2","Brain RNA - amygdala [nTPM]":"13.0","Brain RNA - basal ganglia [nTPM]":"13.3","Brain RNA - cerebellum [nTPM]":"13.9","Brain RNA - cerebral cortex [nTPM]":"22.4","Brain RNA - hippocampal formation [nTPM]":"13.5","Brain RNA - hypothalamus [nTPM]":"14.1","Brain RNA - medulla oblongata [nTPM]":"14.2","Brain RNA - midbrain [nTPM]":"14.4","Brain RNA - pons [nTPM]":"14.2","Brain RNA - spinal cord [nTPM]":"13.4","Brain RNA - thalamus [nTPM]":"14.6","Brain RNA - white matter [nTPM]":"14.9","Single Cell Type RNA - Adipocytes [nTPM]":"11.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.1","Single Cell Type RNA - Astrocytes [nTPM]":"7.2","Single Cell Type RNA - B-cells [nTPM]":"10.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"34.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Bipolar cells [nTPM]":"6.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"22.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"34.2","Single Cell Type RNA - dendritic cells [nTPM]":"9.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"32.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.3","Single Cell Type RNA - Endothelial cells [nTPM]":"16.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.2","Single Cell Type RNA - Erythroid cells [nTPM]":"8.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"44.4","Single Cell Type RNA - Fibroblasts [nTPM]":"11.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.2","Single Cell Type RNA - granulocytes [nTPM]":"12.7","Single Cell Type RNA - Granulosa cells [nTPM]":"12.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.7","Single Cell Type RNA - Hepatocytes [nTPM]":"23.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.8","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.8","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"13.0","Single Cell Type RNA - Langerhans cells [nTPM]":"11.4","Single Cell Type RNA - Late spermatids [nTPM]":"1.9","Single Cell Type RNA - Leydig cells [nTPM]":"14.0","Single Cell Type RNA - Macrophages [nTPM]":"14.1","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"20.9","Single Cell Type RNA - Muller glia cells [nTPM]":"6.2","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.9","Single Cell Type RNA - Paneth cells [nTPM]":"11.1","Single Cell Type RNA - Peritubular cells [nTPM]":"8.2","Single Cell Type RNA - Plasma cells [nTPM]":"33.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"19.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"37.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.7","Single Cell Type RNA - Spermatocytes [nTPM]":"6.8","Single Cell Type RNA - Spermatogonia [nTPM]":"10.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.5","Single Cell Type RNA - T-cells [nTPM]":"10.0","Single Cell Type RNA - Theca cells [nTPM]":"15.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.7","Single Cell Type RNA - Urothelial cells [nTPM]":"12.9"},{"Gene":"DPH1","Gene synonym":["DPH2L","DPH2L1","OVCA1"],"Ensembl":"ENSG00000108963","Gene description":"Diphthamide biosynthesis 1","Uniprot":["Q9BZG8"],"Chromosome":"17","Position":"2030137-2043898","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Dwarfism","Ectodermal dysplasia","Hypotrichosis","Mental retardation","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"19.4","Gastric mucus-secreting cells":"21.4","Plasma cells":"12.0","Squamous epithelial cells":"13.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069750","HPA073864"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA069750":"AB_2686188","HPA073864":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.78e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Tissue RNA - adipose tissue [nTPM]":"24.5","Tissue RNA - adrenal gland [nTPM]":"32.3","Tissue RNA - amygdala [nTPM]":"13.1","Tissue RNA - appendix [nTPM]":"6.0","Tissue RNA - basal ganglia [nTPM]":"12.8","Tissue RNA - bone marrow [nTPM]":"5.3","Tissue RNA - breast [nTPM]":"22.2","Tissue RNA - cerebellum [nTPM]":"16.8","Tissue RNA - cerebral cortex [nTPM]":"17.7","Tissue RNA - cervix [nTPM]":"29.1","Tissue RNA - choroid plexus [nTPM]":"10.7","Tissue RNA - colon [nTPM]":"26.8","Tissue RNA - duodenum [nTPM]":"8.0","Tissue RNA - endometrium 1 [nTPM]":"28.8","Tissue RNA - epididymis [nTPM]":"5.6","Tissue RNA - esophagus [nTPM]":"19.8","Tissue RNA - fallopian tube [nTPM]":"31.0","Tissue RNA - gallbladder [nTPM]":"9.1","Tissue RNA - heart muscle [nTPM]":"19.2","Tissue RNA - hippocampal formation [nTPM]":"13.7","Tissue RNA - hypothalamus [nTPM]":"11.9","Tissue RNA - kidney [nTPM]":"28.0","Tissue RNA - liver [nTPM]":"36.3","Tissue RNA - lung [nTPM]":"16.6","Tissue RNA - lymph node [nTPM]":"7.5","Tissue RNA - medulla oblongata [nTPM]":"10.3","Tissue RNA - midbrain [nTPM]":"10.9","Tissue RNA - ovary [nTPM]":"26.6","Tissue RNA - pancreas [nTPM]":"32.0","Tissue RNA - parathyroid gland [nTPM]":"14.2","Tissue RNA - pituitary gland [nTPM]":"59.3","Tissue RNA - placenta [nTPM]":"8.5","Tissue RNA - pons [nTPM]":"10.3","Tissue RNA - prostate [nTPM]":"36.2","Tissue RNA - rectum [nTPM]":"6.2","Tissue RNA - retina [nTPM]":"12.4","Tissue RNA - salivary gland [nTPM]":"23.7","Tissue RNA - seminal vesicle [nTPM]":"11.0","Tissue RNA - skeletal muscle [nTPM]":"42.3","Tissue RNA - skin 1 [nTPM]":"29.3","Tissue RNA - small intestine [nTPM]":"20.8","Tissue RNA - smooth muscle [nTPM]":"8.9","Tissue RNA - spinal cord [nTPM]":"10.1","Tissue RNA - spleen [nTPM]":"24.3","Tissue RNA - stomach 1 [nTPM]":"27.0","Tissue RNA - testis [nTPM]":"20.3","Tissue RNA - thalamus [nTPM]":"11.7","Tissue RNA - thymus [nTPM]":"6.7","Tissue RNA - thyroid gland [nTPM]":"28.6","Tissue RNA - tongue [nTPM]":"13.7","Tissue RNA - tonsil [nTPM]":"6.0","Tissue RNA - urinary bladder [nTPM]":"24.2","Tissue RNA - vagina [nTPM]":"22.3","Tissue RNA - white matter [nTPM]":"11.5","Cell RNA - A-431 [nTPM]":"15.4","Cell RNA - A549 [nTPM]":"24.9","Cell RNA - AF22 [nTPM]":"6.3","Cell RNA - AN3-CA [nTPM]":"16.0","Cell RNA - ASC diff [nTPM]":"22.2","Cell RNA - ASC TERT1 [nTPM]":"14.2","Cell RNA - BEWO [nTPM]":"18.7","Cell RNA - BJ [nTPM]":"19.3","Cell RNA - BJ hTERT+ [nTPM]":"26.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"29.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"18.7","Cell RNA - CACO-2 [nTPM]":"24.1","Cell RNA - CAPAN-2 [nTPM]":"11.6","Cell RNA - Daudi [nTPM]":"29.0","Cell RNA - EFO-21 [nTPM]":"23.6","Cell RNA - fHDF\/TERT166 [nTPM]":"52.5","Cell RNA - GAMG [nTPM]":"11.2","Cell RNA - HaCaT [nTPM]":"11.6","Cell RNA - HAP1 [nTPM]":"20.7","Cell RNA - HBEC3-KT [nTPM]":"21.1","Cell RNA - HBF TERT88 [nTPM]":"15.9","Cell RNA - HDLM-2 [nTPM]":"9.0","Cell RNA - HEK 293 [nTPM]":"52.4","Cell RNA - HEL [nTPM]":"6.3","Cell RNA - HeLa [nTPM]":"10.5","Cell RNA - Hep G2 [nTPM]":"13.1","Cell RNA - HHSteC [nTPM]":"19.4","Cell RNA - HL-60 [nTPM]":"8.3","Cell RNA - HMC-1 [nTPM]":"10.2","Cell RNA - HSkMC [nTPM]":"20.3","Cell RNA - hTCEpi [nTPM]":"20.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.7","Cell RNA - hTERT-HME1 [nTPM]":"19.0","Cell RNA - hTERT-RPE1 [nTPM]":"20.5","Cell RNA - HUVEC TERT2 [nTPM]":"13.9","Cell RNA - JURKAT [nTPM]":"16.8","Cell RNA - K-562 [nTPM]":"23.4","Cell RNA - Karpas-707 [nTPM]":"11.2","Cell RNA - LHCN-M2 [nTPM]":"11.9","Cell RNA - MCF7 [nTPM]":"18.2","Cell RNA - MOLT-4 [nTPM]":"14.7","Cell RNA - NB-4 [nTPM]":"4.8","Cell RNA - NTERA-2 [nTPM]":"6.5","Cell RNA - OE19 [nTPM]":"17.3","Cell RNA - PC-3 [nTPM]":"25.9","Cell RNA - REH [nTPM]":"16.6","Cell RNA - RH-30 [nTPM]":"5.7","Cell RNA - RPMI-8226 [nTPM]":"22.0","Cell RNA - RPTEC TERT1 [nTPM]":"13.3","Cell RNA - RT4 [nTPM]":"8.0","Cell RNA - SCLC-21H [nTPM]":"13.1","Cell RNA - SH-SY5Y [nTPM]":"15.2","Cell RNA - SiHa [nTPM]":"17.4","Cell RNA - SK-BR-3 [nTPM]":"17.9","Cell RNA - SK-MEL-30 [nTPM]":"17.2","Cell RNA - SuSa [nTPM]":"6.9","Cell RNA - T-47d [nTPM]":"25.9","Cell RNA - THP-1 [nTPM]":"6.8","Cell RNA - TIME [nTPM]":"10.1","Cell RNA - U-138 MG [nTPM]":"19.4","Cell RNA - U-2 OS [nTPM]":"10.1","Cell RNA - U-2197 [nTPM]":"26.2","Cell RNA - U-251 MG [nTPM]":"16.7","Cell RNA - U-266\/70 [nTPM]":"10.3","Cell RNA - U-266\/84 [nTPM]":"8.3","Cell RNA - U-698 [nTPM]":"6.8","Cell RNA - U-87 MG [nTPM]":"20.3","Cell RNA - U-937 [nTPM]":"10.8","Cell RNA - WM-115 [nTPM]":"8.5","Blood RNA - basophil [nTPM]":"0.8","Blood RNA - classical monocyte [nTPM]":"4.5","Blood RNA - eosinophil [nTPM]":"0.8","Blood RNA - gdT-cell [nTPM]":"8.0","Blood RNA - intermediate monocyte [nTPM]":"6.1","Blood RNA - MAIT T-cell [nTPM]":"8.9","Blood RNA - memory B-cell [nTPM]":"8.8","Blood RNA - memory CD4 T-cell [nTPM]":"6.5","Blood RNA - memory CD8 T-cell [nTPM]":"7.4","Blood RNA - myeloid DC [nTPM]":"7.7","Blood RNA - naive B-cell [nTPM]":"7.2","Blood RNA - naive CD4 T-cell [nTPM]":"9.6","Blood RNA - naive CD8 T-cell [nTPM]":"6.9","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"6.7","Blood RNA - non-classical monocyte [nTPM]":"4.5","Blood RNA - plasmacytoid DC [nTPM]":"5.5","Blood RNA - T-reg [nTPM]":"10.2","Blood RNA - total PBMC [nTPM]":"5.2","Brain RNA - amygdala [nTPM]":"13.1","Brain RNA - basal ganglia [nTPM]":"12.8","Brain RNA - cerebellum [nTPM]":"16.8","Brain RNA - cerebral cortex [nTPM]":"17.7","Brain RNA - hippocampal formation [nTPM]":"13.7","Brain RNA - hypothalamus [nTPM]":"11.9","Brain RNA - medulla oblongata [nTPM]":"10.3","Brain RNA - midbrain [nTPM]":"10.9","Brain RNA - pons [nTPM]":"10.3","Brain RNA - spinal cord [nTPM]":"10.1","Brain RNA - thalamus [nTPM]":"11.7","Brain RNA - white matter [nTPM]":"11.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.2","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"9.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.4","Single Cell Type RNA - Bipolar cells [nTPM]":"2.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.5","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.2","Single Cell Type RNA - Endothelial cells [nTPM]":"1.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"9.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.9","Single Cell Type RNA - Fibroblasts [nTPM]":"4.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.8","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"1.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"3.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.9","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"12.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.2","Single Cell Type RNA - Spermatocytes [nTPM]":"1.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - T-cells [nTPM]":"5.4","Single Cell Type RNA - Theca cells [nTPM]":"1.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"DPM1","Gene synonym":["CDGIE","MPDS"],"Ensembl":"ENSG00000000419","Gene description":"Dolichyl-phosphate mannosyltransferase subunit 1, catalytic","Uniprot":["O60762"],"Chromosome":"20","Position":"50934867-50958555","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Congenital muscular dystrophy","Disease variant","Dystroglycanopathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051818"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051818":"AB_2681624"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.94e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Tissue RNA - adipose tissue [nTPM]":"40.9","Tissue RNA - adrenal gland [nTPM]":"53.4","Tissue RNA - amygdala [nTPM]":"23.0","Tissue RNA - appendix [nTPM]":"34.3","Tissue RNA - basal ganglia [nTPM]":"23.9","Tissue RNA - bone marrow [nTPM]":"59.3","Tissue RNA - breast [nTPM]":"42.7","Tissue RNA - cerebellum [nTPM]":"24.4","Tissue RNA - cerebral cortex [nTPM]":"31.9","Tissue RNA - cervix [nTPM]":"31.5","Tissue RNA - choroid plexus [nTPM]":"26.1","Tissue RNA - colon [nTPM]":"38.6","Tissue RNA - duodenum [nTPM]":"36.9","Tissue RNA - endometrium 1 [nTPM]":"39.4","Tissue RNA - epididymis [nTPM]":"47.6","Tissue RNA - esophagus [nTPM]":"45.3","Tissue RNA - fallopian tube [nTPM]":"32.6","Tissue RNA - gallbladder [nTPM]":"36.1","Tissue RNA - heart muscle [nTPM]":"60.6","Tissue RNA - hippocampal formation [nTPM]":"24.4","Tissue RNA - hypothalamus [nTPM]":"24.5","Tissue RNA - kidney [nTPM]":"47.0","Tissue RNA - liver [nTPM]":"63.1","Tissue RNA - lung [nTPM]":"29.7","Tissue RNA - lymph node [nTPM]":"56.0","Tissue RNA - medulla oblongata [nTPM]":"23.3","Tissue RNA - midbrain [nTPM]":"22.8","Tissue RNA - ovary [nTPM]":"38.7","Tissue RNA - pancreas [nTPM]":"48.6","Tissue RNA - parathyroid gland [nTPM]":"43.0","Tissue RNA - pituitary gland [nTPM]":"25.4","Tissue RNA - placenta [nTPM]":"45.1","Tissue RNA - pons [nTPM]":"23.5","Tissue RNA - prostate [nTPM]":"34.3","Tissue RNA - rectum [nTPM]":"42.7","Tissue RNA - retina [nTPM]":"27.2","Tissue RNA - salivary gland [nTPM]":"38.5","Tissue RNA - seminal vesicle [nTPM]":"31.0","Tissue RNA - skeletal muscle [nTPM]":"57.3","Tissue RNA - skin 1 [nTPM]":"34.6","Tissue RNA - small intestine [nTPM]":"39.0","Tissue RNA - smooth muscle [nTPM]":"37.4","Tissue RNA - spinal cord [nTPM]":"23.8","Tissue RNA - spleen [nTPM]":"37.1","Tissue RNA - stomach 1 [nTPM]":"38.1","Tissue RNA - testis [nTPM]":"39.7","Tissue RNA - thalamus [nTPM]":"23.1","Tissue RNA - thymus [nTPM]":"43.9","Tissue RNA - thyroid gland [nTPM]":"48.4","Tissue RNA - tongue [nTPM]":"55.2","Tissue RNA - tonsil [nTPM]":"53.6","Tissue RNA - urinary bladder [nTPM]":"51.6","Tissue RNA - vagina [nTPM]":"33.3","Tissue RNA - white matter [nTPM]":"27.6","Cell RNA - A-431 [nTPM]":"139.9","Cell RNA - A549 [nTPM]":"55.4","Cell RNA - AF22 [nTPM]":"83.6","Cell RNA - AN3-CA [nTPM]":"50.5","Cell RNA - ASC diff [nTPM]":"72.1","Cell RNA - ASC TERT1 [nTPM]":"80.8","Cell RNA - BEWO [nTPM]":"92.1","Cell RNA - BJ [nTPM]":"52.6","Cell RNA - BJ hTERT+ [nTPM]":"62.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"102.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"80.7","Cell RNA - CACO-2 [nTPM]":"252.1","Cell RNA - CAPAN-2 [nTPM]":"110.2","Cell RNA - Daudi [nTPM]":"84.1","Cell RNA - EFO-21 [nTPM]":"112.9","Cell RNA - fHDF\/TERT166 [nTPM]":"71.1","Cell RNA - GAMG [nTPM]":"141.9","Cell RNA - HaCaT [nTPM]":"156.2","Cell RNA - HAP1 [nTPM]":"68.5","Cell RNA - HBEC3-KT [nTPM]":"129.0","Cell RNA - HBF TERT88 [nTPM]":"103.9","Cell RNA - HDLM-2 [nTPM]":"40.7","Cell RNA - HEK 293 [nTPM]":"53.9","Cell RNA - HEL [nTPM]":"87.7","Cell RNA - HeLa [nTPM]":"69.5","Cell RNA - Hep G2 [nTPM]":"171.2","Cell RNA - HHSteC [nTPM]":"101.6","Cell RNA - HL-60 [nTPM]":"141.4","Cell RNA - HMC-1 [nTPM]":"50.5","Cell RNA - HSkMC [nTPM]":"70.0","Cell RNA - hTCEpi [nTPM]":"187.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"71.5","Cell RNA - hTERT-HME1 [nTPM]":"73.7","Cell RNA - hTERT-RPE1 [nTPM]":"66.4","Cell RNA - HUVEC TERT2 [nTPM]":"80.1","Cell RNA - JURKAT [nTPM]":"89.0","Cell RNA - K-562 [nTPM]":"135.3","Cell RNA - Karpas-707 [nTPM]":"104.2","Cell RNA - LHCN-M2 [nTPM]":"103.3","Cell RNA - MCF7 [nTPM]":"61.3","Cell RNA - MOLT-4 [nTPM]":"127.6","Cell RNA - NB-4 [nTPM]":"148.9","Cell RNA - NTERA-2 [nTPM]":"85.3","Cell RNA - OE19 [nTPM]":"131.8","Cell RNA - PC-3 [nTPM]":"124.8","Cell RNA - REH [nTPM]":"69.7","Cell RNA - RH-30 [nTPM]":"120.7","Cell RNA - RPMI-8226 [nTPM]":"112.6","Cell RNA - RPTEC TERT1 [nTPM]":"102.6","Cell RNA - RT4 [nTPM]":"83.4","Cell RNA - SCLC-21H [nTPM]":"62.5","Cell RNA - SH-SY5Y [nTPM]":"68.5","Cell RNA - SiHa [nTPM]":"135.8","Cell RNA - SK-BR-3 [nTPM]":"203.8","Cell RNA - SK-MEL-30 [nTPM]":"189.1","Cell RNA - SuSa [nTPM]":"64.2","Cell RNA - T-47d [nTPM]":"138.8","Cell RNA - THP-1 [nTPM]":"164.5","Cell RNA - TIME [nTPM]":"66.1","Cell RNA - U-138 MG [nTPM]":"130.8","Cell RNA - U-2 OS [nTPM]":"109.2","Cell RNA - U-2197 [nTPM]":"76.6","Cell RNA - U-251 MG [nTPM]":"112.6","Cell RNA - U-266\/70 [nTPM]":"74.2","Cell RNA - U-266\/84 [nTPM]":"99.7","Cell RNA - U-698 [nTPM]":"122.0","Cell RNA - U-87 MG [nTPM]":"143.7","Cell RNA - U-937 [nTPM]":"92.4","Cell RNA - WM-115 [nTPM]":"60.4","Blood RNA - basophil [nTPM]":"13.5","Blood RNA - classical monocyte [nTPM]":"16.3","Blood RNA - eosinophil [nTPM]":"17.6","Blood RNA - gdT-cell [nTPM]":"16.4","Blood RNA - intermediate monocyte [nTPM]":"18.5","Blood RNA - MAIT T-cell [nTPM]":"20.0","Blood RNA - memory B-cell [nTPM]":"17.9","Blood RNA - memory CD4 T-cell [nTPM]":"18.6","Blood RNA - memory CD8 T-cell [nTPM]":"17.9","Blood RNA - myeloid DC [nTPM]":"20.3","Blood RNA - naive B-cell [nTPM]":"16.1","Blood RNA - naive CD4 T-cell [nTPM]":"20.0","Blood RNA - naive CD8 T-cell [nTPM]":"22.4","Blood RNA - neutrophil [nTPM]":"20.0","Blood RNA - NK-cell [nTPM]":"19.1","Blood RNA - non-classical monocyte [nTPM]":"18.6","Blood RNA - plasmacytoid DC [nTPM]":"21.7","Blood RNA - T-reg [nTPM]":"19.5","Blood RNA - total PBMC [nTPM]":"16.1","Brain RNA - amygdala [nTPM]":"23.0","Brain RNA - basal ganglia [nTPM]":"23.9","Brain RNA - cerebellum [nTPM]":"24.4","Brain RNA - cerebral cortex [nTPM]":"31.9","Brain RNA - hippocampal formation [nTPM]":"24.4","Brain RNA - hypothalamus [nTPM]":"24.5","Brain RNA - medulla oblongata [nTPM]":"23.3","Brain RNA - midbrain [nTPM]":"22.8","Brain RNA - pons [nTPM]":"23.5","Brain RNA - spinal cord [nTPM]":"23.8","Brain RNA - thalamus [nTPM]":"23.1","Brain RNA - white matter [nTPM]":"27.6","Single Cell Type RNA - Adipocytes [nTPM]":"36.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"42.3","Single Cell Type RNA - Astrocytes [nTPM]":"27.1","Single Cell Type RNA - B-cells [nTPM]":"37.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"116.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"143.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"248.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"29.0","Single Cell Type RNA - Bipolar cells [nTPM]":"11.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"37.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"48.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"35.8","Single Cell Type RNA - Club cells [nTPM]":"119.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"153.1","Single Cell Type RNA - dendritic cells [nTPM]":"46.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"31.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"117.4","Single Cell Type RNA - Ductal cells [nTPM]":"75.9","Single Cell Type RNA - Early spermatids [nTPM]":"207.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"49.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"38.0","Single Cell Type RNA - Endothelial cells [nTPM]":"53.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"23.4","Single Cell Type RNA - Erythroid cells [nTPM]":"30.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"35.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"73.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"104.9","Single Cell Type RNA - Fibroblasts [nTPM]":"53.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"57.5","Single Cell Type RNA - granulocytes [nTPM]":"74.3","Single Cell Type RNA - Granulosa cells [nTPM]":"25.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"49.2","Single Cell Type RNA - Hepatocytes [nTPM]":"67.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"87.9","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"31.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"52.5","Single Cell Type RNA - Ionocytes [nTPM]":"144.5","Single Cell Type RNA - Kupffer cells [nTPM]":"42.0","Single Cell Type RNA - Langerhans cells [nTPM]":"58.4","Single Cell Type RNA - Late spermatids [nTPM]":"43.8","Single Cell Type RNA - Leydig cells [nTPM]":"56.8","Single Cell Type RNA - Macrophages [nTPM]":"36.7","Single Cell Type RNA - Melanocytes [nTPM]":"49.8","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"65.8","Single Cell Type RNA - Muller glia cells [nTPM]":"27.3","Single Cell Type RNA - NK-cells [nTPM]":"43.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"34.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"70.5","Single Cell Type RNA - Paneth cells [nTPM]":"50.2","Single Cell Type RNA - Peritubular cells [nTPM]":"51.6","Single Cell Type RNA - Plasma cells [nTPM]":"33.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"73.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"40.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"96.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"135.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.6","Single Cell Type RNA - Sertoli cells [nTPM]":"72.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"50.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"71.5","Single Cell Type RNA - Spermatocytes [nTPM]":"109.9","Single Cell Type RNA - Spermatogonia [nTPM]":"103.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"32.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"105.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"245.4","Single Cell Type RNA - T-cells [nTPM]":"47.8","Single Cell Type RNA - Theca cells [nTPM]":"36.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"55.3","Single Cell Type RNA - Urothelial cells [nTPM]":"125.9"},{"Gene":"DPP10","Gene synonym":["DPL2","DPPY","DPRP3"],"Ensembl":"ENSG00000175497","Gene description":"Dipeptidyl peptidase like 10","Uniprot":["Q8N608"],"Chromosome":"2","Position":"114442299-115845780","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Asthma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"10.7","brain":"20.2","pancreas":"17.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"4634.9","Excitatory neurons":"3067.4","Inhibitory neurons":"3258.7","Oligodendrocyte precursor cells":"990.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"4.1","HAP1":"6.2","HMC-1":"4.3","JURKAT":"3.4","NTERA-2":"3.7","RT4":"6.7","SCLC-21H":"9.7","SH-SY5Y":"3.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048767"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA048767":"AB_2680515"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"10.7","Tissue RNA - amygdala [nTPM]":"12.4","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"20.2","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"16.6","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"2.2","Tissue RNA - duodenum [nTPM]":"1.2","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"19.3","Tissue RNA - hypothalamus [nTPM]":"0.5","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"1.9","Tissue RNA - midbrain [nTPM]":"3.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"17.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"0.8","Tissue RNA - pons [nTPM]":"2.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"2.8","Tissue RNA - retina [nTPM]":"4.1","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"1.2","Tissue RNA - smooth muscle [nTPM]":"0.8","Tissue RNA - spinal cord [nTPM]":"4.5","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"1.0","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"6.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.6","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"11.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"4.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"6.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"4.3","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"3.4","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"3.7","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"6.7","Cell RNA - SCLC-21H [nTPM]":"9.7","Cell RNA - SH-SY5Y [nTPM]":"3.9","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"12.4","Brain RNA - basal ganglia [nTPM]":"20.2","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"16.6","Brain RNA - hippocampal formation [nTPM]":"19.3","Brain RNA - hypothalamus [nTPM]":"0.5","Brain RNA - medulla oblongata [nTPM]":"1.9","Brain RNA - midbrain [nTPM]":"3.1","Brain RNA - pons [nTPM]":"2.0","Brain RNA - spinal cord [nTPM]":"4.5","Brain RNA - thalamus [nTPM]":"6.0","Brain RNA - white matter [nTPM]":"11.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"4634.9","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"21.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"12.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"3067.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.2","Single Cell Type RNA - Fibroblasts [nTPM]":"0.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"5.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3258.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"5.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"58.1","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"990.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"48.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.8","Single Cell Type RNA - Paneth cells [nTPM]":"1.9","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.6","Single Cell Type RNA - Spermatogonia [nTPM]":"2.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.4","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"DPP6","Gene synonym":["DPL1","DPPX"],"Ensembl":"ENSG00000130226","Gene description":"Dipeptidyl peptidase like 6","Uniprot":["P42658"],"Chromosome":"7","Position":"153887097-154894285","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Mental retardation","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"54.0","endometrium 1":"58.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"673.4","Inhibitory neurons":"1195.9","Oligodendrocyte precursor cells":"1947.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"glioma":"12.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"NTERA-2":"11.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050509"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA050509":"AB_2681150"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.6","Tissue RNA - adrenal gland [nTPM]":"8.2","Tissue RNA - amygdala [nTPM]":"16.5","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"24.5","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"32.0","Tissue RNA - cerebral cortex [nTPM]":"34.5","Tissue RNA - cervix [nTPM]":"5.8","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"19.8","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"58.2","Tissue RNA - epididymis [nTPM]":"2.5","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"5.2","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"42.7","Tissue RNA - hypothalamus [nTPM]":"21.6","Tissue RNA - kidney [nTPM]":"5.3","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"1.4","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"54.0","Tissue RNA - midbrain [nTPM]":"24.5","Tissue RNA - ovary [nTPM]":"0.7","Tissue RNA - pancreas [nTPM]":"3.9","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"10.8","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"53.1","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"1.6","Tissue RNA - retina [nTPM]":"11.1","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"8.9","Tissue RNA - skeletal muscle [nTPM]":"6.0","Tissue RNA - skin 1 [nTPM]":"3.6","Tissue RNA - small intestine [nTPM]":"3.4","Tissue RNA - smooth muscle [nTPM]":"19.9","Tissue RNA - spinal cord [nTPM]":"8.6","Tissue RNA - spleen [nTPM]":"4.7","Tissue RNA - stomach 1 [nTPM]":"7.8","Tissue RNA - testis [nTPM]":"7.3","Tissue RNA - thalamus [nTPM]":"32.2","Tissue RNA - thymus [nTPM]":"1.9","Tissue RNA - thyroid gland [nTPM]":"17.1","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"1.1","Tissue RNA - white matter [nTPM]":"14.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"11.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"1.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"16.5","Brain RNA - basal ganglia [nTPM]":"24.5","Brain RNA - cerebellum [nTPM]":"32.0","Brain RNA - cerebral cortex [nTPM]":"34.5","Brain RNA - hippocampal formation [nTPM]":"42.7","Brain RNA - hypothalamus [nTPM]":"21.6","Brain RNA - medulla oblongata [nTPM]":"54.0","Brain RNA - midbrain [nTPM]":"24.5","Brain RNA - pons [nTPM]":"53.1","Brain RNA - spinal cord [nTPM]":"8.6","Brain RNA - thalamus [nTPM]":"32.2","Brain RNA - white matter [nTPM]":"14.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"147.9","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"27.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"13.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.3","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"673.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"32.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1195.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"18.4","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"22.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"17.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1947.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"290.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.9","Single Cell Type RNA - Spermatocytes [nTPM]":"1.2","Single Cell Type RNA - Spermatogonia [nTPM]":"4.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"DPYS","Gene synonym":["DHPase"],"Ensembl":"ENSG00000147647","Gene description":"Dihydropyrimidinase","Uniprot":["Q14117"],"Chromosome":"8","Position":"104330324-104467055","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"39","RNA tissue specific nTPM":{"kidney":"199.6","liver":"477.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Hepatocytes":"459.5","Proximal tubular cells":"518.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"liver cancer":"57.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024785","HPA070814"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"820000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA024785":"AB_1847856","HPA070814":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.56e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Tissue RNA - adipose tissue [nTPM]":"8.6","Tissue RNA - adrenal gland [nTPM]":"2.8","Tissue RNA - amygdala [nTPM]":"0.6","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"1.7","Tissue RNA - cervix [nTPM]":"1.2","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.7","Tissue RNA - gallbladder [nTPM]":"6.5","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.6","Tissue RNA - hypothalamus [nTPM]":"0.5","Tissue RNA - kidney [nTPM]":"199.6","Tissue RNA - liver [nTPM]":"477.6","Tissue RNA - lung [nTPM]":"0.6","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.7","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.6","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"0.6","Tissue RNA - prostate [nTPM]":"4.4","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"5.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.6","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.5","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.5","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.6","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"1.7","Brain RNA - hippocampal formation [nTPM]":"0.6","Brain RNA - hypothalamus [nTPM]":"0.5","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.7","Brain RNA - pons [nTPM]":"0.6","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"4.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"40.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"27.4","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"12.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"16.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"459.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"11.1","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"13.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"10.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"0.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"518.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"1.2","Single Cell Type RNA - Spermatogonia [nTPM]":"1.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"2.7","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"DRAM2","Gene synonym":["MGC54289","PRO180","RP5-1180E21.1","TMEM77","WWFQ154"],"Ensembl":"ENSG00000156171","Gene description":"DNA damage regulated autophagy modulator 2","Uniprot":["Q6UX65"],"Chromosome":"1","Position":"111117163-111140203","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Autophagy"],"Molecular function":null,"Disease involvement":["Cone-rod dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018036","HPA061701"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA018036":"AB_1858134","HPA061701":"AB_2684590"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.45e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.43e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.45e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-3"},"Tissue RNA - adipose tissue [nTPM]":"38.0","Tissue RNA - adrenal gland [nTPM]":"23.1","Tissue RNA - amygdala [nTPM]":"13.9","Tissue RNA - appendix [nTPM]":"33.1","Tissue RNA - basal ganglia [nTPM]":"14.5","Tissue RNA - bone marrow [nTPM]":"17.9","Tissue RNA - breast [nTPM]":"26.8","Tissue RNA - cerebellum [nTPM]":"17.7","Tissue RNA - cerebral cortex [nTPM]":"19.9","Tissue RNA - cervix [nTPM]":"23.1","Tissue RNA - choroid plexus [nTPM]":"22.7","Tissue RNA - colon [nTPM]":"26.7","Tissue RNA - duodenum [nTPM]":"28.6","Tissue RNA - endometrium 1 [nTPM]":"17.7","Tissue RNA - epididymis [nTPM]":"17.6","Tissue RNA - esophagus [nTPM]":"15.0","Tissue RNA - fallopian tube [nTPM]":"30.1","Tissue RNA - gallbladder [nTPM]":"36.4","Tissue RNA - heart muscle [nTPM]":"23.7","Tissue RNA - hippocampal formation [nTPM]":"13.5","Tissue RNA - hypothalamus [nTPM]":"15.2","Tissue RNA - kidney [nTPM]":"26.5","Tissue RNA - liver [nTPM]":"24.9","Tissue RNA - lung [nTPM]":"25.0","Tissue RNA - lymph node [nTPM]":"55.3","Tissue RNA - medulla oblongata [nTPM]":"15.6","Tissue RNA - midbrain [nTPM]":"14.9","Tissue RNA - ovary [nTPM]":"24.3","Tissue RNA - pancreas [nTPM]":"25.6","Tissue RNA - parathyroid gland [nTPM]":"28.3","Tissue RNA - pituitary gland [nTPM]":"4.6","Tissue RNA - placenta [nTPM]":"41.2","Tissue RNA - pons [nTPM]":"16.2","Tissue RNA - prostate [nTPM]":"17.8","Tissue RNA - rectum [nTPM]":"30.7","Tissue RNA - retina [nTPM]":"16.9","Tissue RNA - salivary gland [nTPM]":"25.8","Tissue RNA - seminal vesicle [nTPM]":"16.7","Tissue RNA - skeletal muscle [nTPM]":"16.6","Tissue RNA - skin 1 [nTPM]":"17.9","Tissue RNA - small intestine [nTPM]":"26.3","Tissue RNA - smooth muscle [nTPM]":"17.0","Tissue RNA - spinal cord [nTPM]":"15.5","Tissue RNA - spleen [nTPM]":"45.3","Tissue RNA - stomach 1 [nTPM]":"23.4","Tissue RNA - testis [nTPM]":"10.3","Tissue RNA - thalamus [nTPM]":"15.0","Tissue RNA - thymus [nTPM]":"27.8","Tissue RNA - thyroid gland [nTPM]":"22.0","Tissue RNA - tongue [nTPM]":"23.6","Tissue RNA - tonsil [nTPM]":"50.3","Tissue RNA - urinary bladder [nTPM]":"29.4","Tissue RNA - vagina [nTPM]":"4.2","Tissue RNA - white matter [nTPM]":"17.8","Cell RNA - A-431 [nTPM]":"38.0","Cell RNA - A549 [nTPM]":"12.9","Cell RNA - AF22 [nTPM]":"24.0","Cell RNA - AN3-CA [nTPM]":"10.8","Cell RNA - ASC diff [nTPM]":"57.3","Cell RNA - ASC TERT1 [nTPM]":"56.2","Cell RNA - BEWO [nTPM]":"23.4","Cell RNA - BJ [nTPM]":"28.7","Cell RNA - BJ hTERT+ [nTPM]":"29.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.9","Cell RNA - CACO-2 [nTPM]":"12.5","Cell RNA - CAPAN-2 [nTPM]":"38.2","Cell RNA - Daudi [nTPM]":"28.7","Cell RNA - EFO-21 [nTPM]":"17.2","Cell RNA - fHDF\/TERT166 [nTPM]":"25.6","Cell RNA - GAMG [nTPM]":"12.1","Cell RNA - HaCaT [nTPM]":"37.4","Cell RNA - HAP1 [nTPM]":"30.5","Cell RNA - HBEC3-KT [nTPM]":"24.0","Cell RNA - HBF TERT88 [nTPM]":"31.9","Cell RNA - HDLM-2 [nTPM]":"26.8","Cell RNA - HEK 293 [nTPM]":"25.6","Cell RNA - HEL [nTPM]":"16.8","Cell RNA - HeLa [nTPM]":"18.4","Cell RNA - Hep G2 [nTPM]":"16.4","Cell RNA - HHSteC [nTPM]":"41.4","Cell RNA - HL-60 [nTPM]":"19.4","Cell RNA - HMC-1 [nTPM]":"15.4","Cell RNA - HSkMC [nTPM]":"38.5","Cell RNA - hTCEpi [nTPM]":"41.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.3","Cell RNA - hTERT-HME1 [nTPM]":"38.4","Cell RNA - hTERT-RPE1 [nTPM]":"53.6","Cell RNA - HUVEC TERT2 [nTPM]":"29.9","Cell RNA - JURKAT [nTPM]":"29.1","Cell RNA - K-562 [nTPM]":"34.1","Cell RNA - Karpas-707 [nTPM]":"19.6","Cell RNA - LHCN-M2 [nTPM]":"30.1","Cell RNA - MCF7 [nTPM]":"19.6","Cell RNA - MOLT-4 [nTPM]":"16.6","Cell RNA - NB-4 [nTPM]":"28.8","Cell RNA - NTERA-2 [nTPM]":"14.5","Cell RNA - OE19 [nTPM]":"43.3","Cell RNA - PC-3 [nTPM]":"13.2","Cell RNA - REH [nTPM]":"11.1","Cell RNA - RH-30 [nTPM]":"40.0","Cell RNA - RPMI-8226 [nTPM]":"14.0","Cell RNA - RPTEC TERT1 [nTPM]":"42.5","Cell RNA - RT4 [nTPM]":"25.8","Cell RNA - SCLC-21H [nTPM]":"19.1","Cell RNA - SH-SY5Y [nTPM]":"18.2","Cell RNA - SiHa [nTPM]":"16.8","Cell RNA - SK-BR-3 [nTPM]":"52.4","Cell RNA - SK-MEL-30 [nTPM]":"80.1","Cell RNA - SuSa [nTPM]":"33.1","Cell RNA - T-47d [nTPM]":"16.7","Cell RNA - THP-1 [nTPM]":"84.6","Cell RNA - TIME [nTPM]":"24.8","Cell RNA - U-138 MG [nTPM]":"20.6","Cell RNA - U-2 OS [nTPM]":"13.8","Cell RNA - U-2197 [nTPM]":"16.2","Cell RNA - U-251 MG [nTPM]":"18.9","Cell RNA - U-266\/70 [nTPM]":"25.7","Cell RNA - U-266\/84 [nTPM]":"9.6","Cell RNA - U-698 [nTPM]":"29.8","Cell RNA - U-87 MG [nTPM]":"33.4","Cell RNA - U-937 [nTPM]":"34.7","Cell RNA - WM-115 [nTPM]":"29.6","Blood RNA - basophil [nTPM]":"41.7","Blood RNA - classical monocyte [nTPM]":"47.3","Blood RNA - eosinophil [nTPM]":"11.5","Blood RNA - gdT-cell [nTPM]":"14.2","Blood RNA - intermediate monocyte [nTPM]":"61.0","Blood RNA - MAIT T-cell [nTPM]":"19.4","Blood RNA - memory B-cell [nTPM]":"65.7","Blood RNA - memory CD4 T-cell [nTPM]":"17.5","Blood RNA - memory CD8 T-cell [nTPM]":"15.3","Blood RNA - myeloid DC [nTPM]":"45.1","Blood RNA - naive B-cell [nTPM]":"54.1","Blood RNA - naive CD4 T-cell [nTPM]":"22.3","Blood RNA - naive CD8 T-cell [nTPM]":"19.0","Blood RNA - neutrophil [nTPM]":"7.2","Blood RNA - NK-cell [nTPM]":"25.0","Blood RNA - non-classical monocyte [nTPM]":"49.8","Blood RNA - plasmacytoid DC [nTPM]":"28.6","Blood RNA - T-reg [nTPM]":"17.7","Blood RNA - total PBMC [nTPM]":"35.5","Brain RNA - amygdala [nTPM]":"13.9","Brain RNA - basal ganglia [nTPM]":"14.5","Brain RNA - cerebellum [nTPM]":"17.7","Brain RNA - cerebral cortex [nTPM]":"19.9","Brain RNA - hippocampal formation [nTPM]":"13.5","Brain RNA - hypothalamus [nTPM]":"15.2","Brain RNA - medulla oblongata [nTPM]":"15.6","Brain RNA - midbrain [nTPM]":"14.9","Brain RNA - pons [nTPM]":"16.2","Brain RNA - spinal cord [nTPM]":"15.5","Brain RNA - thalamus [nTPM]":"15.0","Brain RNA - white matter [nTPM]":"17.8","Single Cell Type RNA - Adipocytes [nTPM]":"34.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.0","Single Cell Type RNA - Astrocytes [nTPM]":"17.3","Single Cell Type RNA - B-cells [nTPM]":"146.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"47.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"54.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"82.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"34.1","Single Cell Type RNA - Bipolar cells [nTPM]":"11.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"53.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"43.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"29.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"53.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"98.1","Single Cell Type RNA - dendritic cells [nTPM]":"38.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"41.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"43.0","Single Cell Type RNA - Ductal cells [nTPM]":"59.2","Single Cell Type RNA - Early spermatids [nTPM]":"8.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"51.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.5","Single Cell Type RNA - Endothelial cells [nTPM]":"36.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.2","Single Cell Type RNA - Erythroid cells [nTPM]":"28.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"20.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"46.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"102.3","Single Cell Type RNA - Fibroblasts [nTPM]":"39.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"24.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.6","Single Cell Type RNA - granulocytes [nTPM]":"23.6","Single Cell Type RNA - Granulosa cells [nTPM]":"18.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"42.8","Single Cell Type RNA - Hepatocytes [nTPM]":"26.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"183.1","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"31.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"45.7","Single Cell Type RNA - Ionocytes [nTPM]":"77.3","Single Cell Type RNA - Kupffer cells [nTPM]":"189.4","Single Cell Type RNA - Langerhans cells [nTPM]":"97.8","Single Cell Type RNA - Late spermatids [nTPM]":"7.8","Single Cell Type RNA - Leydig cells [nTPM]":"33.5","Single Cell Type RNA - Macrophages [nTPM]":"110.3","Single Cell Type RNA - Melanocytes [nTPM]":"81.8","Single Cell Type RNA - Microglial cells [nTPM]":"39.4","Single Cell Type RNA - monocytes [nTPM]":"89.0","Single Cell Type RNA - Muller glia cells [nTPM]":"27.1","Single Cell Type RNA - NK-cells [nTPM]":"56.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"31.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"42.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"41.9","Single Cell Type RNA - Paneth cells [nTPM]":"64.3","Single Cell Type RNA - Peritubular cells [nTPM]":"24.8","Single Cell Type RNA - Plasma cells [nTPM]":"54.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"46.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"88.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"80.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"95.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.1","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"26.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.5","Single Cell Type RNA - Spermatocytes [nTPM]":"4.7","Single Cell Type RNA - Spermatogonia [nTPM]":"14.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"40.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"53.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"73.3","Single Cell Type RNA - T-cells [nTPM]":"38.6","Single Cell Type RNA - Theca cells [nTPM]":"26.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"43.7","Single Cell Type RNA - Urothelial cells [nTPM]":"70.1"},{"Gene":"DSE","Gene synonym":["DS-Epi1","DSEPI","SART2"],"Ensembl":"ENSG00000111817","Gene description":"Dermatan sulfate epimerase","Uniprot":["Q9UL01"],"Chromosome":"6","Position":"116254173-116444861","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Isomerase"],"Disease involvement":["Disease variant","Ehlers-Danlos syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Macrophages":"112.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"5.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014764"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014764":"AB_1856587"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.36e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.34e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.50e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.19e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Tissue RNA - adipose tissue [nTPM]":"27.8","Tissue RNA - adrenal gland [nTPM]":"10.7","Tissue RNA - amygdala [nTPM]":"3.6","Tissue RNA - appendix [nTPM]":"26.8","Tissue RNA - basal ganglia [nTPM]":"4.5","Tissue RNA - bone marrow [nTPM]":"18.4","Tissue RNA - breast [nTPM]":"18.3","Tissue RNA - cerebellum [nTPM]":"3.9","Tissue RNA - cerebral cortex [nTPM]":"4.4","Tissue RNA - cervix [nTPM]":"13.8","Tissue RNA - choroid plexus [nTPM]":"10.4","Tissue RNA - colon [nTPM]":"7.7","Tissue RNA - duodenum [nTPM]":"6.4","Tissue RNA - endometrium 1 [nTPM]":"10.5","Tissue RNA - epididymis [nTPM]":"8.3","Tissue RNA - esophagus [nTPM]":"13.7","Tissue RNA - fallopian tube [nTPM]":"14.6","Tissue RNA - gallbladder [nTPM]":"14.9","Tissue RNA - heart muscle [nTPM]":"12.4","Tissue RNA - hippocampal formation [nTPM]":"3.2","Tissue RNA - hypothalamus [nTPM]":"4.3","Tissue RNA - kidney [nTPM]":"8.6","Tissue RNA - liver [nTPM]":"11.3","Tissue RNA - lung [nTPM]":"15.3","Tissue RNA - lymph node [nTPM]":"16.4","Tissue RNA - medulla oblongata [nTPM]":"7.0","Tissue RNA - midbrain [nTPM]":"5.8","Tissue RNA - ovary [nTPM]":"13.8","Tissue RNA - pancreas [nTPM]":"3.8","Tissue RNA - parathyroid gland [nTPM]":"11.1","Tissue RNA - pituitary gland [nTPM]":"6.0","Tissue RNA - placenta [nTPM]":"23.1","Tissue RNA - pons [nTPM]":"5.6","Tissue RNA - prostate [nTPM]":"8.5","Tissue RNA - rectum [nTPM]":"8.0","Tissue RNA - retina [nTPM]":"3.5","Tissue RNA - salivary gland [nTPM]":"6.9","Tissue RNA - seminal vesicle [nTPM]":"10.2","Tissue RNA - skeletal muscle [nTPM]":"6.9","Tissue RNA - skin 1 [nTPM]":"13.8","Tissue RNA - small intestine [nTPM]":"9.0","Tissue RNA - smooth muscle [nTPM]":"15.0","Tissue RNA - spinal cord [nTPM]":"4.6","Tissue RNA - spleen [nTPM]":"18.6","Tissue RNA - stomach 1 [nTPM]":"6.4","Tissue RNA - testis [nTPM]":"6.1","Tissue RNA - thalamus [nTPM]":"8.5","Tissue RNA - thymus [nTPM]":"10.3","Tissue RNA - thyroid gland [nTPM]":"6.6","Tissue RNA - tongue [nTPM]":"10.7","Tissue RNA - tonsil [nTPM]":"9.7","Tissue RNA - urinary bladder [nTPM]":"19.7","Tissue RNA - vagina [nTPM]":"14.3","Tissue RNA - white matter [nTPM]":"5.9","Cell RNA - A-431 [nTPM]":"32.7","Cell RNA - A549 [nTPM]":"7.0","Cell RNA - AF22 [nTPM]":"23.6","Cell RNA - AN3-CA [nTPM]":"22.2","Cell RNA - ASC diff [nTPM]":"62.0","Cell RNA - ASC TERT1 [nTPM]":"40.7","Cell RNA - BEWO [nTPM]":"26.5","Cell RNA - BJ [nTPM]":"37.6","Cell RNA - BJ hTERT+ [nTPM]":"88.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"46.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"67.4","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"8.9","Cell RNA - Daudi [nTPM]":"0.9","Cell RNA - EFO-21 [nTPM]":"3.3","Cell RNA - fHDF\/TERT166 [nTPM]":"66.3","Cell RNA - GAMG [nTPM]":"46.4","Cell RNA - HaCaT [nTPM]":"60.8","Cell RNA - HAP1 [nTPM]":"3.3","Cell RNA - HBEC3-KT [nTPM]":"88.7","Cell RNA - HBF TERT88 [nTPM]":"60.1","Cell RNA - HDLM-2 [nTPM]":"33.9","Cell RNA - HEK 293 [nTPM]":"14.6","Cell RNA - HEL [nTPM]":"2.2","Cell RNA - HeLa [nTPM]":"9.8","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"69.0","Cell RNA - HL-60 [nTPM]":"1.5","Cell RNA - HMC-1 [nTPM]":"1.7","Cell RNA - HSkMC [nTPM]":"86.8","Cell RNA - hTCEpi [nTPM]":"37.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"51.5","Cell RNA - hTERT-HME1 [nTPM]":"50.0","Cell RNA - hTERT-RPE1 [nTPM]":"24.0","Cell RNA - HUVEC TERT2 [nTPM]":"27.7","Cell RNA - JURKAT [nTPM]":"8.3","Cell RNA - K-562 [nTPM]":"0.8","Cell RNA - Karpas-707 [nTPM]":"14.4","Cell RNA - LHCN-M2 [nTPM]":"22.4","Cell RNA - MCF7 [nTPM]":"1.0","Cell RNA - MOLT-4 [nTPM]":"4.4","Cell RNA - NB-4 [nTPM]":"1.8","Cell RNA - NTERA-2 [nTPM]":"12.7","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"1.8","Cell RNA - REH [nTPM]":"5.6","Cell RNA - RH-30 [nTPM]":"21.6","Cell RNA - RPMI-8226 [nTPM]":"15.6","Cell RNA - RPTEC TERT1 [nTPM]":"30.4","Cell RNA - RT4 [nTPM]":"2.2","Cell RNA - SCLC-21H [nTPM]":"7.8","Cell RNA - SH-SY5Y [nTPM]":"5.9","Cell RNA - SiHa [nTPM]":"36.4","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.8","Cell RNA - SuSa [nTPM]":"16.2","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"3.9","Cell RNA - TIME [nTPM]":"10.5","Cell RNA - U-138 MG [nTPM]":"46.4","Cell RNA - U-2 OS [nTPM]":"13.4","Cell RNA - U-2197 [nTPM]":"11.8","Cell RNA - U-251 MG [nTPM]":"30.6","Cell RNA - U-266\/70 [nTPM]":"3.1","Cell RNA - U-266\/84 [nTPM]":"1.1","Cell RNA - U-698 [nTPM]":"1.6","Cell RNA - U-87 MG [nTPM]":"24.6","Cell RNA - U-937 [nTPM]":"4.0","Cell RNA - WM-115 [nTPM]":"5.5","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"2.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"2.5","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"2.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"5.9","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"1.6","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"1.6","Blood RNA - plasmacytoid DC [nTPM]":"2.7","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"3.6","Brain RNA - basal ganglia [nTPM]":"4.5","Brain RNA - cerebellum [nTPM]":"3.9","Brain RNA - cerebral cortex [nTPM]":"4.4","Brain RNA - hippocampal formation [nTPM]":"3.2","Brain RNA - hypothalamus [nTPM]":"4.3","Brain RNA - medulla oblongata [nTPM]":"7.0","Brain RNA - midbrain [nTPM]":"5.8","Brain RNA - pons [nTPM]":"5.6","Brain RNA - spinal cord [nTPM]":"4.6","Brain RNA - thalamus [nTPM]":"8.5","Brain RNA - white matter [nTPM]":"5.9","Single Cell Type RNA - Adipocytes [nTPM]":"9.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.1","Single Cell Type RNA - Astrocytes [nTPM]":"64.9","Single Cell Type RNA - B-cells [nTPM]":"15.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"52.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"26.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"42.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"78.6","Single Cell Type RNA - Bipolar cells [nTPM]":"6.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"20.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.9","Single Cell Type RNA - dendritic cells [nTPM]":"16.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.8","Single Cell Type RNA - Early spermatids [nTPM]":"52.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.9","Single Cell Type RNA - Endothelial cells [nTPM]":"15.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"11.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"46.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.0","Single Cell Type RNA - Fibroblasts [nTPM]":"73.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.1","Single Cell Type RNA - granulocytes [nTPM]":"22.8","Single Cell Type RNA - Granulosa cells [nTPM]":"100.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"56.4","Single Cell Type RNA - Hepatocytes [nTPM]":"5.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"39.8","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"48.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.6","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"83.6","Single Cell Type RNA - Langerhans cells [nTPM]":"77.1","Single Cell Type RNA - Late spermatids [nTPM]":"24.9","Single Cell Type RNA - Leydig cells [nTPM]":"55.0","Single Cell Type RNA - Macrophages [nTPM]":"112.2","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"51.5","Single Cell Type RNA - monocytes [nTPM]":"79.4","Single Cell Type RNA - Muller glia cells [nTPM]":"3.4","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"73.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"86.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.4","Single Cell Type RNA - Peritubular cells [nTPM]":"30.1","Single Cell Type RNA - Plasma cells [nTPM]":"8.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"32.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"30.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.0","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"33.4","Single Cell Type RNA - Spermatocytes [nTPM]":"6.1","Single Cell Type RNA - Spermatogonia [nTPM]":"5.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"76.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"39.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.9","Single Cell Type RNA - T-cells [nTPM]":"14.0","Single Cell Type RNA - Theca cells [nTPM]":"17.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.0","Single Cell Type RNA - Urothelial cells [nTPM]":"51.0"},{"Gene":"DSTYK","Gene synonym":["DustyPK","KIAA0472","RIP5","RIPK5","SPG23"],"Ensembl":"ENSG00000133059","Gene description":"Dual serine\/threonine and tyrosine protein kinase","Uniprot":["Q6XUX3"],"Chromosome":"1","Position":"205142505-205211702","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"89.2","Melanocytes":"90.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044140"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 62: Horizontal cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044140":"AB_10965031"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.73e-5"},"Tissue RNA - adipose tissue [nTPM]":"4.5","Tissue RNA - adrenal gland [nTPM]":"7.2","Tissue RNA - amygdala [nTPM]":"11.5","Tissue RNA - appendix [nTPM]":"3.8","Tissue RNA - basal ganglia [nTPM]":"11.1","Tissue RNA - bone marrow [nTPM]":"19.2","Tissue RNA - breast [nTPM]":"6.7","Tissue RNA - cerebellum [nTPM]":"11.5","Tissue RNA - cerebral cortex [nTPM]":"12.1","Tissue RNA - cervix [nTPM]":"6.4","Tissue RNA - choroid plexus [nTPM]":"6.8","Tissue RNA - colon [nTPM]":"6.0","Tissue RNA - duodenum [nTPM]":"2.7","Tissue RNA - endometrium 1 [nTPM]":"7.9","Tissue RNA - epididymis [nTPM]":"5.8","Tissue RNA - esophagus [nTPM]":"5.5","Tissue RNA - fallopian tube [nTPM]":"7.2","Tissue RNA - gallbladder [nTPM]":"4.5","Tissue RNA - heart muscle [nTPM]":"4.9","Tissue RNA - hippocampal formation [nTPM]":"11.8","Tissue RNA - hypothalamus [nTPM]":"11.3","Tissue RNA - kidney [nTPM]":"7.5","Tissue RNA - liver [nTPM]":"2.2","Tissue RNA - lung [nTPM]":"6.1","Tissue RNA - lymph node [nTPM]":"4.0","Tissue RNA - medulla oblongata [nTPM]":"13.5","Tissue RNA - midbrain [nTPM]":"10.7","Tissue RNA - ovary [nTPM]":"11.1","Tissue RNA - pancreas [nTPM]":"4.5","Tissue RNA - parathyroid gland [nTPM]":"13.1","Tissue RNA - pituitary gland [nTPM]":"5.5","Tissue RNA - placenta [nTPM]":"6.0","Tissue RNA - pons [nTPM]":"13.7","Tissue RNA - prostate [nTPM]":"5.6","Tissue RNA - rectum [nTPM]":"3.6","Tissue RNA - retina [nTPM]":"13.5","Tissue RNA - salivary gland [nTPM]":"4.4","Tissue RNA - seminal vesicle [nTPM]":"6.9","Tissue RNA - skeletal muscle [nTPM]":"9.6","Tissue RNA - skin 1 [nTPM]":"12.0","Tissue RNA - small intestine [nTPM]":"4.1","Tissue RNA - smooth muscle [nTPM]":"7.1","Tissue RNA - spinal cord [nTPM]":"9.9","Tissue RNA - spleen [nTPM]":"6.2","Tissue RNA - stomach 1 [nTPM]":"4.2","Tissue RNA - testis [nTPM]":"5.1","Tissue RNA - thalamus [nTPM]":"11.5","Tissue RNA - thymus [nTPM]":"6.2","Tissue RNA - thyroid gland [nTPM]":"6.8","Tissue RNA - tongue [nTPM]":"6.8","Tissue RNA - tonsil [nTPM]":"4.5","Tissue RNA - urinary bladder [nTPM]":"5.2","Tissue RNA - vagina [nTPM]":"5.4","Tissue RNA - white matter [nTPM]":"13.5","Cell RNA - A-431 [nTPM]":"9.9","Cell RNA - A549 [nTPM]":"6.3","Cell RNA - AF22 [nTPM]":"6.6","Cell RNA - AN3-CA [nTPM]":"8.1","Cell RNA - ASC diff [nTPM]":"9.5","Cell RNA - ASC TERT1 [nTPM]":"15.9","Cell RNA - BEWO [nTPM]":"4.7","Cell RNA - BJ [nTPM]":"12.0","Cell RNA - BJ hTERT+ [nTPM]":"12.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.4","Cell RNA - CACO-2 [nTPM]":"2.9","Cell RNA - CAPAN-2 [nTPM]":"5.3","Cell RNA - Daudi [nTPM]":"7.3","Cell RNA - EFO-21 [nTPM]":"3.5","Cell RNA - fHDF\/TERT166 [nTPM]":"20.6","Cell RNA - GAMG [nTPM]":"6.9","Cell RNA - HaCaT [nTPM]":"6.9","Cell RNA - HAP1 [nTPM]":"7.3","Cell RNA - HBEC3-KT [nTPM]":"7.8","Cell RNA - HBF TERT88 [nTPM]":"12.4","Cell RNA - HDLM-2 [nTPM]":"3.5","Cell RNA - HEK 293 [nTPM]":"7.8","Cell RNA - HEL [nTPM]":"13.3","Cell RNA - HeLa [nTPM]":"8.1","Cell RNA - Hep G2 [nTPM]":"3.1","Cell RNA - HHSteC [nTPM]":"8.5","Cell RNA - HL-60 [nTPM]":"3.7","Cell RNA - HMC-1 [nTPM]":"6.8","Cell RNA - HSkMC [nTPM]":"9.4","Cell RNA - hTCEpi [nTPM]":"11.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.7","Cell RNA - hTERT-HME1 [nTPM]":"12.0","Cell RNA - hTERT-RPE1 [nTPM]":"14.7","Cell RNA - HUVEC TERT2 [nTPM]":"9.2","Cell RNA - JURKAT [nTPM]":"5.2","Cell RNA - K-562 [nTPM]":"17.4","Cell RNA - Karpas-707 [nTPM]":"4.8","Cell RNA - LHCN-M2 [nTPM]":"10.0","Cell RNA - MCF7 [nTPM]":"6.8","Cell RNA - MOLT-4 [nTPM]":"2.9","Cell RNA - NB-4 [nTPM]":"3.3","Cell RNA - NTERA-2 [nTPM]":"7.2","Cell RNA - OE19 [nTPM]":"1.8","Cell RNA - PC-3 [nTPM]":"7.4","Cell RNA - REH [nTPM]":"2.6","Cell RNA - RH-30 [nTPM]":"12.1","Cell RNA - RPMI-8226 [nTPM]":"6.5","Cell RNA - RPTEC TERT1 [nTPM]":"8.4","Cell RNA - RT4 [nTPM]":"6.1","Cell RNA - SCLC-21H [nTPM]":"3.7","Cell RNA - SH-SY5Y [nTPM]":"7.2","Cell RNA - SiHa [nTPM]":"10.3","Cell RNA - SK-BR-3 [nTPM]":"10.5","Cell RNA - SK-MEL-30 [nTPM]":"34.5","Cell RNA - SuSa [nTPM]":"7.7","Cell RNA - T-47d [nTPM]":"7.8","Cell RNA - THP-1 [nTPM]":"4.9","Cell RNA - TIME [nTPM]":"9.2","Cell RNA - U-138 MG [nTPM]":"7.7","Cell RNA - U-2 OS [nTPM]":"7.7","Cell RNA - U-2197 [nTPM]":"11.8","Cell RNA - U-251 MG [nTPM]":"8.2","Cell RNA - U-266\/70 [nTPM]":"4.8","Cell RNA - U-266\/84 [nTPM]":"3.7","Cell RNA - U-698 [nTPM]":"4.1","Cell RNA - U-87 MG [nTPM]":"9.0","Cell RNA - U-937 [nTPM]":"5.1","Cell RNA - WM-115 [nTPM]":"28.2","Blood RNA - basophil [nTPM]":"8.1","Blood RNA - classical monocyte [nTPM]":"1.9","Blood RNA - eosinophil [nTPM]":"3.6","Blood RNA - gdT-cell [nTPM]":"2.4","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"2.3","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.8","Blood RNA - memory CD8 T-cell [nTPM]":"2.0","Blood RNA - myeloid DC [nTPM]":"1.7","Blood RNA - naive B-cell [nTPM]":"1.7","Blood RNA - naive CD4 T-cell [nTPM]":"2.6","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"2.7","Blood RNA - NK-cell [nTPM]":"2.8","Blood RNA - non-classical monocyte [nTPM]":"1.0","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"1.1","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"11.5","Brain RNA - basal ganglia [nTPM]":"11.1","Brain RNA - cerebellum [nTPM]":"11.5","Brain RNA - cerebral cortex [nTPM]":"12.1","Brain RNA - hippocampal formation [nTPM]":"11.8","Brain RNA - hypothalamus [nTPM]":"11.3","Brain RNA - medulla oblongata [nTPM]":"13.5","Brain RNA - midbrain [nTPM]":"10.7","Brain RNA - pons [nTPM]":"13.7","Brain RNA - spinal cord [nTPM]":"9.9","Brain RNA - thalamus [nTPM]":"11.5","Brain RNA - white matter [nTPM]":"13.5","Single Cell Type RNA - Adipocytes [nTPM]":"15.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.5","Single Cell Type RNA - Astrocytes [nTPM]":"26.4","Single Cell Type RNA - B-cells [nTPM]":"15.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"48.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"15.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.8","Single Cell Type RNA - dendritic cells [nTPM]":"15.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"12.5","Single Cell Type RNA - Early spermatids [nTPM]":"11.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"37.7","Single Cell Type RNA - Endothelial cells [nTPM]":"16.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.7","Single Cell Type RNA - Erythroid cells [nTPM]":"31.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"35.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.1","Single Cell Type RNA - Fibroblasts [nTPM]":"19.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.6","Single Cell Type RNA - granulocytes [nTPM]":"24.1","Single Cell Type RNA - Granulosa cells [nTPM]":"43.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.5","Single Cell Type RNA - Hepatocytes [nTPM]":"6.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.8","Single Cell Type RNA - Horizontal cells [nTPM]":"89.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"36.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.2","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"23.6","Single Cell Type RNA - Langerhans cells [nTPM]":"15.6","Single Cell Type RNA - Late spermatids [nTPM]":"25.2","Single Cell Type RNA - Leydig cells [nTPM]":"16.4","Single Cell Type RNA - Macrophages [nTPM]":"11.4","Single Cell Type RNA - Melanocytes [nTPM]":"90.7","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"20.6","Single Cell Type RNA - Muller glia cells [nTPM]":"45.1","Single Cell Type RNA - NK-cells [nTPM]":"23.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"43.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.6","Single Cell Type RNA - Paneth cells [nTPM]":"5.0","Single Cell Type RNA - Peritubular cells [nTPM]":"18.0","Single Cell Type RNA - Plasma cells [nTPM]":"11.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"24.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"37.3","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.4","Single Cell Type RNA - Spermatocytes [nTPM]":"22.3","Single Cell Type RNA - Spermatogonia [nTPM]":"13.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.6","Single Cell Type RNA - T-cells [nTPM]":"15.1","Single Cell Type RNA - Theca cells [nTPM]":"27.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.5","Single Cell Type RNA - Urothelial cells [nTPM]":"6.7"},{"Gene":"DTNA","Gene synonym":["D18S892E","DRP3","DTN","DTN-1","DTN-2","DTN-3"],"Ensembl":"ENSG00000134769","Gene description":"Dystrobrevin alpha","Uniprot":["Q9Y4J8"],"Chromosome":"18","Position":"34493290-34891844","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cardiomyopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"461.9","choroid plexus":"120.6","heart muscle":"150.0","skeletal muscle":"166.9","tongue":"209.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"1756.1","Excitatory neurons":"506.0","Inhibitory neurons":"650.9","Oligodendrocyte precursor cells":"491.6","Oligodendrocytes":"367.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"glioma":"28.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"37.7","NTERA-2":"42.0","SCLC-21H":"51.9","U-87 MG":"52.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015196","HPA071177"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cell Junctions","Intermediate filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":["Cell Junctions","Intermediate filaments"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB015196":"AB_2261797","HPA071177":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.64e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.27e-5"},"Tissue RNA - adipose tissue [nTPM]":"11.6","Tissue RNA - adrenal gland [nTPM]":"6.6","Tissue RNA - amygdala [nTPM]":"252.7","Tissue RNA - appendix [nTPM]":"5.4","Tissue RNA - basal ganglia [nTPM]":"248.2","Tissue RNA - bone marrow [nTPM]":"0.8","Tissue RNA - breast [nTPM]":"9.6","Tissue RNA - cerebellum [nTPM]":"243.3","Tissue RNA - cerebral cortex [nTPM]":"260.1","Tissue RNA - cervix [nTPM]":"5.4","Tissue RNA - choroid plexus [nTPM]":"120.6","Tissue RNA - colon [nTPM]":"22.4","Tissue RNA - duodenum [nTPM]":"3.9","Tissue RNA - endometrium 1 [nTPM]":"8.1","Tissue RNA - epididymis [nTPM]":"20.5","Tissue RNA - esophagus [nTPM]":"22.9","Tissue RNA - fallopian tube [nTPM]":"11.7","Tissue RNA - gallbladder [nTPM]":"9.4","Tissue RNA - heart muscle [nTPM]":"150.0","Tissue RNA - hippocampal formation [nTPM]":"250.1","Tissue RNA - hypothalamus [nTPM]":"423.0","Tissue RNA - kidney [nTPM]":"2.3","Tissue RNA - liver [nTPM]":"2.2","Tissue RNA - lung [nTPM]":"6.6","Tissue RNA - lymph node [nTPM]":"2.3","Tissue RNA - medulla oblongata [nTPM]":"461.9","Tissue RNA - midbrain [nTPM]":"326.9","Tissue RNA - ovary [nTPM]":"7.0","Tissue RNA - pancreas [nTPM]":"18.1","Tissue RNA - parathyroid gland [nTPM]":"2.4","Tissue RNA - pituitary gland [nTPM]":"10.8","Tissue RNA - placenta [nTPM]":"4.1","Tissue RNA - pons [nTPM]":"360.4","Tissue RNA - prostate [nTPM]":"23.6","Tissue RNA - rectum [nTPM]":"7.6","Tissue RNA - retina [nTPM]":"19.8","Tissue RNA - salivary gland [nTPM]":"11.3","Tissue RNA - seminal vesicle [nTPM]":"25.3","Tissue RNA - skeletal muscle [nTPM]":"166.9","Tissue RNA - skin 1 [nTPM]":"2.7","Tissue RNA - small intestine [nTPM]":"8.4","Tissue RNA - smooth muscle [nTPM]":"19.4","Tissue RNA - spinal cord [nTPM]":"308.1","Tissue RNA - spleen [nTPM]":"4.8","Tissue RNA - stomach 1 [nTPM]":"6.8","Tissue RNA - testis [nTPM]":"6.1","Tissue RNA - thalamus [nTPM]":"269.2","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"12.3","Tissue RNA - tongue [nTPM]":"209.9","Tissue RNA - tonsil [nTPM]":"2.0","Tissue RNA - urinary bladder [nTPM]":"32.0","Tissue RNA - vagina [nTPM]":"5.2","Tissue RNA - white matter [nTPM]":"331.0","Cell RNA - A-431 [nTPM]":"0.7","Cell RNA - A549 [nTPM]":"0.5","Cell RNA - AF22 [nTPM]":"17.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"9.5","Cell RNA - ASC TERT1 [nTPM]":"25.1","Cell RNA - BEWO [nTPM]":"2.6","Cell RNA - BJ [nTPM]":"3.2","Cell RNA - BJ hTERT+ [nTPM]":"14.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.7","Cell RNA - CACO-2 [nTPM]":"3.8","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"8.9","Cell RNA - fHDF\/TERT166 [nTPM]":"1.9","Cell RNA - GAMG [nTPM]":"15.3","Cell RNA - HaCaT [nTPM]":"1.1","Cell RNA - HAP1 [nTPM]":"2.1","Cell RNA - HBEC3-KT [nTPM]":"7.5","Cell RNA - HBF TERT88 [nTPM]":"1.8","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"10.7","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.9","Cell RNA - Hep G2 [nTPM]":"5.7","Cell RNA - HHSteC [nTPM]":"7.1","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"19.2","Cell RNA - hTCEpi [nTPM]":"1.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.9","Cell RNA - hTERT-HME1 [nTPM]":"4.5","Cell RNA - hTERT-RPE1 [nTPM]":"14.2","Cell RNA - HUVEC TERT2 [nTPM]":"6.7","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"2.4","Cell RNA - Karpas-707 [nTPM]":"1.9","Cell RNA - LHCN-M2 [nTPM]":"3.8","Cell RNA - MCF7 [nTPM]":"37.7","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"42.0","Cell RNA - OE19 [nTPM]":"0.6","Cell RNA - PC-3 [nTPM]":"8.1","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"7.7","Cell RNA - RPMI-8226 [nTPM]":"24.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.9","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"51.9","Cell RNA - SH-SY5Y [nTPM]":"6.9","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"1.7","Cell RNA - SK-MEL-30 [nTPM]":"4.9","Cell RNA - SuSa [nTPM]":"23.8","Cell RNA - T-47d [nTPM]":"21.8","Cell RNA - THP-1 [nTPM]":"6.3","Cell RNA - TIME [nTPM]":"0.5","Cell RNA - U-138 MG [nTPM]":"16.7","Cell RNA - U-2 OS [nTPM]":"9.9","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"5.2","Cell RNA - U-266\/70 [nTPM]":"1.3","Cell RNA - U-266\/84 [nTPM]":"2.0","Cell RNA - U-698 [nTPM]":"1.0","Cell RNA - U-87 MG [nTPM]":"52.5","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"8.4","Blood RNA - basophil [nTPM]":"1.0","Blood RNA - classical monocyte [nTPM]":"0.7","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"1.1","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"3.5","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"1.6","Blood RNA - naive CD8 T-cell [nTPM]":"1.3","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"4.3","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"252.7","Brain RNA - basal ganglia [nTPM]":"248.2","Brain RNA - cerebellum [nTPM]":"243.3","Brain RNA - cerebral cortex [nTPM]":"260.1","Brain RNA - hippocampal formation [nTPM]":"250.1","Brain RNA - hypothalamus [nTPM]":"423.0","Brain RNA - medulla oblongata [nTPM]":"461.9","Brain RNA - midbrain [nTPM]":"326.9","Brain RNA - pons [nTPM]":"360.4","Brain RNA - spinal cord [nTPM]":"308.1","Brain RNA - thalamus [nTPM]":"269.2","Brain RNA - white matter [nTPM]":"331.0","Single Cell Type RNA - Adipocytes [nTPM]":"5.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"1756.1","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"18.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"134.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"1.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"12.6","Single Cell Type RNA - Early spermatids [nTPM]":"3.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.6","Single Cell Type RNA - Endothelial cells [nTPM]":"6.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"506.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"5.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.0","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"650.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"4.0","Single Cell Type RNA - Langerhans cells [nTPM]":"21.5","Single Cell Type RNA - Late spermatids [nTPM]":"3.7","Single Cell Type RNA - Leydig cells [nTPM]":"5.9","Single Cell Type RNA - Macrophages [nTPM]":"8.0","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"105.9","Single Cell Type RNA - monocytes [nTPM]":"0.9","Single Cell Type RNA - Muller glia cells [nTPM]":"34.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"491.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"367.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.8","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.9","Single Cell Type RNA - Spermatogonia [nTPM]":"4.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"DUOX2","Gene synonym":["LNOX2","P138-TOX","P138(TOX)","THOX2"],"Ensembl":"ENSG00000140279","Gene description":"Dual oxidase 2","Uniprot":["Q9NRD8"],"Chromosome":"15","Position":"45092650-45114172","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Hydrogen peroxide","Thyroid hormones biosynthesis"],"Molecular function":["Oxidoreductase","Peroxidase"],"Disease involvement":["Congenital hypothyroidism","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"gallbladder":"290.2","thyroid gland":"75.7","urinary bladder":"92.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"159.3","Ductal cells":"225.2","Exocrine glandular cells":"125.5","Gastric mucus-secreting cells":"85.1","Pancreatic endocrine cells":"411.7","Urothelial cells":"110.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"60.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"HaCaT":"6.3"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"1.2"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 16: Pancreatic endocrine cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.59e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"21.5","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.6","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"2.8","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"11.6","Tissue RNA - duodenum [nTPM]":"1.5","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"3.1","Tissue RNA - esophagus [nTPM]":"21.5","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"290.2","Tissue RNA - heart muscle [nTPM]":"0.8","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.7","Tissue RNA - liver [nTPM]":"0.8","Tissue RNA - lung [nTPM]":"2.5","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.6","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"1.2","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"11.8","Tissue RNA - rectum [nTPM]":"5.5","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"4.6","Tissue RNA - seminal vesicle [nTPM]":"1.9","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"4.9","Tissue RNA - small intestine [nTPM]":"8.3","Tissue RNA - smooth muscle [nTPM]":"2.7","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"42.3","Tissue RNA - testis [nTPM]":"1.4","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"75.7","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"4.2","Tissue RNA - urinary bladder [nTPM]":"92.8","Tissue RNA - vagina [nTPM]":"21.7","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.5","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.8","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"6.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.7","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.7","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.6","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"36.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"3.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"54.3","Single Cell Type RNA - Club cells [nTPM]":"31.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"159.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"225.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"5.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"125.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"5.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"85.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.5","Single Cell Type RNA - granulocytes [nTPM]":"32.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.1","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"3.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"5.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"411.7","Single Cell Type RNA - Paneth cells [nTPM]":"45.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"43.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.9","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"4.6","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"34.7","Single Cell Type RNA - Urothelial cells [nTPM]":"110.4"},{"Gene":"DUSP6","Gene synonym":["MKP-3","PYST1"],"Ensembl":"ENSG00000139318","Gene description":"Dual specificity phosphatase 6","Uniprot":["Q16828"],"Chromosome":"12","Position":"89347235-89352501","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":["Disease variant","Hypogonadotropic hypogonadism","Kallmann syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"226.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"246.8","granulocytes":"456.9","Kupffer cells":"266.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"97.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1636.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"granulocytes":"1636.7","monocytes":"842.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AN3-CA":"427.6","NB-4":"325.8","SK-MEL-30":"253.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017566","HPA053188","HPA064692"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 60: Granulocytes - Receptor signaling","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB017566":"AB_647991","HPA053188":null,"HPA064692":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.21e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Tissue RNA - adipose tissue [nTPM]":"113.9","Tissue RNA - adrenal gland [nTPM]":"24.7","Tissue RNA - amygdala [nTPM]":"12.0","Tissue RNA - appendix [nTPM]":"63.7","Tissue RNA - basal ganglia [nTPM]":"12.9","Tissue RNA - bone marrow [nTPM]":"178.7","Tissue RNA - breast [nTPM]":"50.8","Tissue RNA - cerebellum [nTPM]":"10.0","Tissue RNA - cerebral cortex [nTPM]":"28.5","Tissue RNA - cervix [nTPM]":"39.4","Tissue RNA - choroid plexus [nTPM]":"29.8","Tissue RNA - colon [nTPM]":"47.3","Tissue RNA - duodenum [nTPM]":"24.8","Tissue RNA - endometrium 1 [nTPM]":"26.2","Tissue RNA - epididymis [nTPM]":"14.2","Tissue RNA - esophagus [nTPM]":"34.8","Tissue RNA - fallopian tube [nTPM]":"36.6","Tissue RNA - gallbladder [nTPM]":"75.5","Tissue RNA - heart muscle [nTPM]":"30.9","Tissue RNA - hippocampal formation [nTPM]":"19.8","Tissue RNA - hypothalamus [nTPM]":"11.6","Tissue RNA - kidney [nTPM]":"58.9","Tissue RNA - liver [nTPM]":"143.3","Tissue RNA - lung [nTPM]":"88.2","Tissue RNA - lymph node [nTPM]":"42.3","Tissue RNA - medulla oblongata [nTPM]":"12.6","Tissue RNA - midbrain [nTPM]":"12.1","Tissue RNA - ovary [nTPM]":"14.2","Tissue RNA - pancreas [nTPM]":"17.9","Tissue RNA - parathyroid gland [nTPM]":"34.6","Tissue RNA - pituitary gland [nTPM]":"17.8","Tissue RNA - placenta [nTPM]":"74.1","Tissue RNA - pons [nTPM]":"12.4","Tissue RNA - prostate [nTPM]":"18.8","Tissue RNA - rectum [nTPM]":"56.1","Tissue RNA - retina [nTPM]":"6.8","Tissue RNA - salivary gland [nTPM]":"226.2","Tissue RNA - seminal vesicle [nTPM]":"22.9","Tissue RNA - skeletal muscle [nTPM]":"8.5","Tissue RNA - skin 1 [nTPM]":"17.4","Tissue RNA - small intestine [nTPM]":"52.1","Tissue RNA - smooth muscle [nTPM]":"43.2","Tissue RNA - spinal cord [nTPM]":"12.7","Tissue RNA - spleen [nTPM]":"71.0","Tissue RNA - stomach 1 [nTPM]":"28.7","Tissue RNA - testis [nTPM]":"6.9","Tissue RNA - thalamus [nTPM]":"16.0","Tissue RNA - thymus [nTPM]":"47.7","Tissue RNA - thyroid gland [nTPM]":"77.4","Tissue RNA - tongue [nTPM]":"40.2","Tissue RNA - tonsil [nTPM]":"27.2","Tissue RNA - urinary bladder [nTPM]":"76.4","Tissue RNA - vagina [nTPM]":"13.8","Tissue RNA - white matter [nTPM]":"13.6","Cell RNA - A-431 [nTPM]":"6.4","Cell RNA - A549 [nTPM]":"6.2","Cell RNA - AF22 [nTPM]":"127.0","Cell RNA - AN3-CA [nTPM]":"427.6","Cell RNA - ASC diff [nTPM]":"108.1","Cell RNA - ASC TERT1 [nTPM]":"89.9","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"47.5","Cell RNA - BJ hTERT+ [nTPM]":"58.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.8","Cell RNA - CACO-2 [nTPM]":"38.7","Cell RNA - CAPAN-2 [nTPM]":"6.8","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"11.2","Cell RNA - fHDF\/TERT166 [nTPM]":"20.5","Cell RNA - GAMG [nTPM]":"17.9","Cell RNA - HaCaT [nTPM]":"51.4","Cell RNA - HAP1 [nTPM]":"0.5","Cell RNA - HBEC3-KT [nTPM]":"118.4","Cell RNA - HBF TERT88 [nTPM]":"13.0","Cell RNA - HDLM-2 [nTPM]":"0.5","Cell RNA - HEK 293 [nTPM]":"0.8","Cell RNA - HEL [nTPM]":"20.0","Cell RNA - HeLa [nTPM]":"1.4","Cell RNA - Hep G2 [nTPM]":"61.4","Cell RNA - HHSteC [nTPM]":"75.7","Cell RNA - HL-60 [nTPM]":"86.3","Cell RNA - HMC-1 [nTPM]":"210.9","Cell RNA - HSkMC [nTPM]":"18.4","Cell RNA - hTCEpi [nTPM]":"40.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"81.5","Cell RNA - hTERT-HME1 [nTPM]":"75.5","Cell RNA - hTERT-RPE1 [nTPM]":"94.9","Cell RNA - HUVEC TERT2 [nTPM]":"214.4","Cell RNA - JURKAT [nTPM]":"2.6","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"20.4","Cell RNA - LHCN-M2 [nTPM]":"29.3","Cell RNA - MCF7 [nTPM]":"3.1","Cell RNA - MOLT-4 [nTPM]":"2.9","Cell RNA - NB-4 [nTPM]":"325.8","Cell RNA - NTERA-2 [nTPM]":"78.7","Cell RNA - OE19 [nTPM]":"149.5","Cell RNA - PC-3 [nTPM]":"102.7","Cell RNA - REH [nTPM]":"216.6","Cell RNA - RH-30 [nTPM]":"15.5","Cell RNA - RPMI-8226 [nTPM]":"8.3","Cell RNA - RPTEC TERT1 [nTPM]":"129.3","Cell RNA - RT4 [nTPM]":"129.7","Cell RNA - SCLC-21H [nTPM]":"2.4","Cell RNA - SH-SY5Y [nTPM]":"88.7","Cell RNA - SiHa [nTPM]":"1.1","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"253.0","Cell RNA - SuSa [nTPM]":"43.3","Cell RNA - T-47d [nTPM]":"6.4","Cell RNA - THP-1 [nTPM]":"46.8","Cell RNA - TIME [nTPM]":"59.0","Cell RNA - U-138 MG [nTPM]":"30.6","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"5.8","Cell RNA - U-251 MG [nTPM]":"22.8","Cell RNA - U-266\/70 [nTPM]":"3.7","Cell RNA - U-266\/84 [nTPM]":"18.5","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"126.5","Cell RNA - U-937 [nTPM]":"60.0","Cell RNA - WM-115 [nTPM]":"200.3","Blood RNA - basophil [nTPM]":"1636.7","Blood RNA - classical monocyte [nTPM]":"558.9","Blood RNA - eosinophil [nTPM]":"247.2","Blood RNA - gdT-cell [nTPM]":"9.8","Blood RNA - intermediate monocyte [nTPM]":"842.3","Blood RNA - MAIT T-cell [nTPM]":"4.5","Blood RNA - memory B-cell [nTPM]":"2.7","Blood RNA - memory CD4 T-cell [nTPM]":"2.7","Blood RNA - memory CD8 T-cell [nTPM]":"3.5","Blood RNA - myeloid DC [nTPM]":"97.0","Blood RNA - naive B-cell [nTPM]":"11.6","Blood RNA - naive CD4 T-cell [nTPM]":"1.6","Blood RNA - naive CD8 T-cell [nTPM]":"3.2","Blood RNA - neutrophil [nTPM]":"230.5","Blood RNA - NK-cell [nTPM]":"14.8","Blood RNA - non-classical monocyte [nTPM]":"841.0","Blood RNA - plasmacytoid DC [nTPM]":"12.2","Blood RNA - T-reg [nTPM]":"6.7","Blood RNA - total PBMC [nTPM]":"455.2","Brain RNA - amygdala [nTPM]":"12.0","Brain RNA - basal ganglia [nTPM]":"12.9","Brain RNA - cerebellum [nTPM]":"10.0","Brain RNA - cerebral cortex [nTPM]":"28.5","Brain RNA - hippocampal formation [nTPM]":"19.8","Brain RNA - hypothalamus [nTPM]":"11.6","Brain RNA - medulla oblongata [nTPM]":"12.6","Brain RNA - midbrain [nTPM]":"12.1","Brain RNA - pons [nTPM]":"12.4","Brain RNA - spinal cord [nTPM]":"12.7","Brain RNA - thalamus [nTPM]":"16.0","Brain RNA - white matter [nTPM]":"13.6","Single Cell Type RNA - Adipocytes [nTPM]":"182.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"102.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"246.8","Single Cell Type RNA - Astrocytes [nTPM]":"12.4","Single Cell Type RNA - B-cells [nTPM]":"18.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"90.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"79.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"97.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"38.7","Single Cell Type RNA - Bipolar cells [nTPM]":"2.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"30.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"85.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"81.5","Single Cell Type RNA - Club cells [nTPM]":"80.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"180.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"72.6","Single Cell Type RNA - dendritic cells [nTPM]":"36.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"58.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"12.6","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"67.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.1","Single Cell Type RNA - Endothelial cells [nTPM]":"159.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.2","Single Cell Type RNA - Erythroid cells [nTPM]":"6.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.2","Single Cell Type RNA - Fibroblasts [nTPM]":"54.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"134.2","Single Cell Type RNA - granulocytes [nTPM]":"456.9","Single Cell Type RNA - Granulosa cells [nTPM]":"24.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"177.8","Single Cell Type RNA - Hepatocytes [nTPM]":"130.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"49.6","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.2","Single Cell Type RNA - Ionocytes [nTPM]":"46.8","Single Cell Type RNA - Kupffer cells [nTPM]":"266.7","Single Cell Type RNA - Langerhans cells [nTPM]":"61.2","Single Cell Type RNA - Late spermatids [nTPM]":"1.7","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"193.2","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"33.7","Single Cell Type RNA - monocytes [nTPM]":"198.9","Single Cell Type RNA - Muller glia cells [nTPM]":"8.7","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"24.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.1","Single Cell Type RNA - Paneth cells [nTPM]":"45.7","Single Cell Type RNA - Peritubular cells [nTPM]":"3.4","Single Cell Type RNA - Plasma cells [nTPM]":"16.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"26.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"27.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.4","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"29.7","Single Cell Type RNA - Spermatocytes [nTPM]":"2.6","Single Cell Type RNA - Spermatogonia [nTPM]":"7.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"49.3","Single Cell Type RNA - T-cells [nTPM]":"42.3","Single Cell Type RNA - Theca cells [nTPM]":"3.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"22.0","Single Cell Type RNA - Urothelial cells [nTPM]":"61.4"},{"Gene":"DUX4","Gene synonym":[],"Ensembl":"ENSG00000260596","Gene description":"Double homeobox 4","Uniprot":["Q9UBX2"],"Chromosome":"4","Position":"190173774-190185942","Protein class":["Disease related genes","Potential drug targets","Predicted intracellular proteins","Transcription factors","Transporters"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"26","RNA single cell type specific nTPM":{"Early spermatids":"4.9","Late spermatids":"5.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"1.5","U-2 OS":"2.2","U-266\/70":"4.7","U-266\/84":"6.9","U-698":"1.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058451"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":["Golgi apparatus","Cytosol"],"Antibody RRID":{"HPA058451":"AB_2683722"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"1.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"1.5","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.6","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"1.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"2.2","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"4.7","Cell RNA - U-266\/84 [nTPM]":"6.9","Cell RNA - U-698 [nTPM]":"1.5","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"1.0","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"4.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"5.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"DYRK1A","Gene synonym":["DYRK","DYRK1","MNBH"],"Ensembl":"ENSG00000157540","Gene description":"Dual specificity tyrosine phosphorylation regulated kinase 1A","Uniprot":["Q13627"],"Chromosome":"21","Position":"37365573-37526358","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"156.7","Inhibitory neurons":"158.4","Microglial cells":"176.1","Oligodendrocyte precursor cells":"158.3","Oligodendrocytes":"157.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015323","HPA015810"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoli fibrillar center"],"Antibody RRID":{"HPA015323":"AB_1847922","HPA015810":"AB_1847921"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Tissue RNA - adipose tissue [nTPM]":"23.1","Tissue RNA - adrenal gland [nTPM]":"20.4","Tissue RNA - amygdala [nTPM]":"17.8","Tissue RNA - appendix [nTPM]":"22.5","Tissue RNA - basal ganglia [nTPM]":"19.9","Tissue RNA - bone marrow [nTPM]":"71.4","Tissue RNA - breast [nTPM]":"22.3","Tissue RNA - cerebellum [nTPM]":"29.9","Tissue RNA - cerebral cortex [nTPM]":"20.7","Tissue RNA - cervix [nTPM]":"23.9","Tissue RNA - choroid plexus [nTPM]":"22.2","Tissue RNA - colon [nTPM]":"22.2","Tissue RNA - duodenum [nTPM]":"18.7","Tissue RNA - endometrium 1 [nTPM]":"26.6","Tissue RNA - epididymis [nTPM]":"22.0","Tissue RNA - esophagus [nTPM]":"18.8","Tissue RNA - fallopian tube [nTPM]":"22.6","Tissue RNA - gallbladder [nTPM]":"19.9","Tissue RNA - heart muscle [nTPM]":"28.9","Tissue RNA - hippocampal formation [nTPM]":"21.3","Tissue RNA - hypothalamus [nTPM]":"19.2","Tissue RNA - kidney [nTPM]":"19.9","Tissue RNA - liver [nTPM]":"19.8","Tissue RNA - lung [nTPM]":"22.3","Tissue RNA - lymph node [nTPM]":"30.1","Tissue RNA - medulla oblongata [nTPM]":"12.1","Tissue RNA - midbrain [nTPM]":"14.7","Tissue RNA - ovary [nTPM]":"29.6","Tissue RNA - pancreas [nTPM]":"21.5","Tissue RNA - parathyroid gland [nTPM]":"27.8","Tissue RNA - pituitary gland [nTPM]":"20.2","Tissue RNA - placenta [nTPM]":"23.0","Tissue RNA - pons [nTPM]":"13.3","Tissue RNA - prostate [nTPM]":"18.8","Tissue RNA - rectum [nTPM]":"21.6","Tissue RNA - retina [nTPM]":"27.8","Tissue RNA - salivary gland [nTPM]":"21.3","Tissue RNA - seminal vesicle [nTPM]":"19.2","Tissue RNA - skeletal muscle [nTPM]":"49.4","Tissue RNA - skin 1 [nTPM]":"24.2","Tissue RNA - small intestine [nTPM]":"21.7","Tissue RNA - smooth muscle [nTPM]":"24.1","Tissue RNA - spinal cord [nTPM]":"12.8","Tissue RNA - spleen [nTPM]":"30.4","Tissue RNA - stomach 1 [nTPM]":"22.8","Tissue RNA - testis [nTPM]":"29.9","Tissue RNA - thalamus [nTPM]":"18.6","Tissue RNA - thymus [nTPM]":"45.8","Tissue RNA - thyroid gland [nTPM]":"25.7","Tissue RNA - tongue [nTPM]":"45.2","Tissue RNA - tonsil [nTPM]":"26.7","Tissue RNA - urinary bladder [nTPM]":"24.3","Tissue RNA - vagina [nTPM]":"21.1","Tissue RNA - white matter [nTPM]":"20.9","Cell RNA - A-431 [nTPM]":"23.5","Cell RNA - A549 [nTPM]":"18.2","Cell RNA - AF22 [nTPM]":"36.3","Cell RNA - AN3-CA [nTPM]":"25.6","Cell RNA - ASC diff [nTPM]":"17.1","Cell RNA - ASC TERT1 [nTPM]":"18.8","Cell RNA - BEWO [nTPM]":"32.7","Cell RNA - BJ [nTPM]":"20.8","Cell RNA - BJ hTERT+ [nTPM]":"26.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"22.0","Cell RNA - CACO-2 [nTPM]":"25.7","Cell RNA - CAPAN-2 [nTPM]":"19.7","Cell RNA - Daudi [nTPM]":"31.7","Cell RNA - EFO-21 [nTPM]":"13.8","Cell RNA - fHDF\/TERT166 [nTPM]":"37.0","Cell RNA - GAMG [nTPM]":"27.1","Cell RNA - HaCaT [nTPM]":"15.8","Cell RNA - HAP1 [nTPM]":"27.3","Cell RNA - HBEC3-KT [nTPM]":"21.2","Cell RNA - HBF TERT88 [nTPM]":"24.4","Cell RNA - HDLM-2 [nTPM]":"49.7","Cell RNA - HEK 293 [nTPM]":"11.6","Cell RNA - HEL [nTPM]":"93.6","Cell RNA - HeLa [nTPM]":"30.9","Cell RNA - Hep G2 [nTPM]":"16.1","Cell RNA - HHSteC [nTPM]":"26.5","Cell RNA - HL-60 [nTPM]":"36.9","Cell RNA - HMC-1 [nTPM]":"32.3","Cell RNA - HSkMC [nTPM]":"18.7","Cell RNA - hTCEpi [nTPM]":"24.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.5","Cell RNA - hTERT-HME1 [nTPM]":"41.2","Cell RNA - hTERT-RPE1 [nTPM]":"23.5","Cell RNA - HUVEC TERT2 [nTPM]":"22.3","Cell RNA - JURKAT [nTPM]":"44.2","Cell RNA - K-562 [nTPM]":"36.4","Cell RNA - Karpas-707 [nTPM]":"70.4","Cell RNA - LHCN-M2 [nTPM]":"22.2","Cell RNA - MCF7 [nTPM]":"23.6","Cell RNA - MOLT-4 [nTPM]":"49.3","Cell RNA - NB-4 [nTPM]":"25.9","Cell RNA - NTERA-2 [nTPM]":"38.5","Cell RNA - OE19 [nTPM]":"24.1","Cell RNA - PC-3 [nTPM]":"10.8","Cell RNA - REH [nTPM]":"62.8","Cell RNA - RH-30 [nTPM]":"19.7","Cell RNA - RPMI-8226 [nTPM]":"29.6","Cell RNA - RPTEC TERT1 [nTPM]":"22.3","Cell RNA - RT4 [nTPM]":"30.4","Cell RNA - SCLC-21H [nTPM]":"36.5","Cell RNA - SH-SY5Y [nTPM]":"20.4","Cell RNA - SiHa [nTPM]":"47.1","Cell RNA - SK-BR-3 [nTPM]":"31.6","Cell RNA - SK-MEL-30 [nTPM]":"33.2","Cell RNA - SuSa [nTPM]":"12.2","Cell RNA - T-47d [nTPM]":"29.9","Cell RNA - THP-1 [nTPM]":"34.8","Cell RNA - TIME [nTPM]":"27.8","Cell RNA - U-138 MG [nTPM]":"27.6","Cell RNA - U-2 OS [nTPM]":"8.3","Cell RNA - U-2197 [nTPM]":"17.2","Cell RNA - U-251 MG [nTPM]":"17.4","Cell RNA - U-266\/70 [nTPM]":"47.7","Cell RNA - U-266\/84 [nTPM]":"41.6","Cell RNA - U-698 [nTPM]":"44.9","Cell RNA - U-87 MG [nTPM]":"22.0","Cell RNA - U-937 [nTPM]":"41.8","Cell RNA - WM-115 [nTPM]":"30.7","Blood RNA - basophil [nTPM]":"3.1","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.8","Blood RNA - gdT-cell [nTPM]":"1.2","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"1.1","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"1.0","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.4","Blood RNA - naive CD8 T-cell [nTPM]":"1.3","Blood RNA - neutrophil [nTPM]":"2.3","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"1.1","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"1.3","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"17.8","Brain RNA - basal ganglia [nTPM]":"19.9","Brain RNA - cerebellum [nTPM]":"29.9","Brain RNA - cerebral cortex [nTPM]":"20.7","Brain RNA - hippocampal formation [nTPM]":"21.3","Brain RNA - hypothalamus [nTPM]":"19.2","Brain RNA - medulla oblongata [nTPM]":"12.1","Brain RNA - midbrain [nTPM]":"14.7","Brain RNA - pons [nTPM]":"13.3","Brain RNA - spinal cord [nTPM]":"12.8","Brain RNA - thalamus [nTPM]":"18.6","Brain RNA - white matter [nTPM]":"20.9","Single Cell Type RNA - Adipocytes [nTPM]":"36.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.5","Single Cell Type RNA - Astrocytes [nTPM]":"114.3","Single Cell Type RNA - B-cells [nTPM]":"28.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"37.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.2","Single Cell Type RNA - Bipolar cells [nTPM]":"32.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"28.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"73.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"23.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.3","Single Cell Type RNA - dendritic cells [nTPM]":"43.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"30.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"13.5","Single Cell Type RNA - Early spermatids [nTPM]":"29.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"44.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"39.3","Single Cell Type RNA - Endothelial cells [nTPM]":"31.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.4","Single Cell Type RNA - Erythroid cells [nTPM]":"26.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"156.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.4","Single Cell Type RNA - Fibroblasts [nTPM]":"25.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"71.4","Single Cell Type RNA - granulocytes [nTPM]":"24.7","Single Cell Type RNA - Granulosa cells [nTPM]":"35.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"27.1","Single Cell Type RNA - Hepatocytes [nTPM]":"18.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.8","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"158.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.8","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"25.0","Single Cell Type RNA - Langerhans cells [nTPM]":"27.7","Single Cell Type RNA - Late spermatids [nTPM]":"22.2","Single Cell Type RNA - Leydig cells [nTPM]":"16.1","Single Cell Type RNA - Macrophages [nTPM]":"32.4","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"176.1","Single Cell Type RNA - monocytes [nTPM]":"18.8","Single Cell Type RNA - Muller glia cells [nTPM]":"16.4","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"158.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"157.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.2","Single Cell Type RNA - Paneth cells [nTPM]":"22.4","Single Cell Type RNA - Peritubular cells [nTPM]":"19.5","Single Cell Type RNA - Plasma cells [nTPM]":"33.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"29.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"27.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.8","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"38.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.5","Single Cell Type RNA - Spermatocytes [nTPM]":"15.3","Single Cell Type RNA - Spermatogonia [nTPM]":"24.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"24.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"31.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.3","Single Cell Type RNA - T-cells [nTPM]":"36.8","Single Cell Type RNA - Theca cells [nTPM]":"21.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.3","Single Cell Type RNA - Urothelial cells [nTPM]":"37.2"},{"Gene":"DYRK1B","Gene synonym":["MIRK"],"Ensembl":"ENSG00000105204","Gene description":"Dual specificity tyrosine phosphorylation regulated kinase 1B","Uniprot":["Q9Y463"],"Chromosome":"19","Position":"39825350-39834201","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Diabetes mellitus","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"131.3","testis":"83.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Early spermatids":"179.4","Late spermatids":"580.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SH-SY5Y":"14.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028522","HPA028786"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitotic chromosome"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Mitotic chromosome"],"Antibody RRID":{"HPA028522":"AB_2672656","HPA028786":"AB_10670831"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.83e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.5","Tissue RNA - adrenal gland [nTPM]":"19.6","Tissue RNA - amygdala [nTPM]":"4.8","Tissue RNA - appendix [nTPM]":"2.7","Tissue RNA - basal ganglia [nTPM]":"4.8","Tissue RNA - bone marrow [nTPM]":"4.7","Tissue RNA - breast [nTPM]":"10.9","Tissue RNA - cerebellum [nTPM]":"4.1","Tissue RNA - cerebral cortex [nTPM]":"6.2","Tissue RNA - cervix [nTPM]":"12.5","Tissue RNA - choroid plexus [nTPM]":"4.8","Tissue RNA - colon [nTPM]":"12.4","Tissue RNA - duodenum [nTPM]":"5.3","Tissue RNA - endometrium 1 [nTPM]":"11.9","Tissue RNA - epididymis [nTPM]":"7.8","Tissue RNA - esophagus [nTPM]":"11.7","Tissue RNA - fallopian tube [nTPM]":"13.8","Tissue RNA - gallbladder [nTPM]":"3.3","Tissue RNA - heart muscle [nTPM]":"20.0","Tissue RNA - hippocampal formation [nTPM]":"4.7","Tissue RNA - hypothalamus [nTPM]":"3.6","Tissue RNA - kidney [nTPM]":"16.2","Tissue RNA - liver [nTPM]":"7.5","Tissue RNA - lung [nTPM]":"8.8","Tissue RNA - lymph node [nTPM]":"4.6","Tissue RNA - medulla oblongata [nTPM]":"3.5","Tissue RNA - midbrain [nTPM]":"3.4","Tissue RNA - ovary [nTPM]":"11.6","Tissue RNA - pancreas [nTPM]":"10.3","Tissue RNA - parathyroid gland [nTPM]":"6.5","Tissue RNA - pituitary gland [nTPM]":"31.5","Tissue RNA - placenta [nTPM]":"2.7","Tissue RNA - pons [nTPM]":"3.6","Tissue RNA - prostate [nTPM]":"13.0","Tissue RNA - rectum [nTPM]":"2.1","Tissue RNA - retina [nTPM]":"4.1","Tissue RNA - salivary gland [nTPM]":"14.3","Tissue RNA - seminal vesicle [nTPM]":"3.3","Tissue RNA - skeletal muscle [nTPM]":"131.3","Tissue RNA - skin 1 [nTPM]":"14.8","Tissue RNA - small intestine [nTPM]":"10.2","Tissue RNA - smooth muscle [nTPM]":"2.6","Tissue RNA - spinal cord [nTPM]":"1.2","Tissue RNA - spleen [nTPM]":"14.0","Tissue RNA - stomach 1 [nTPM]":"12.1","Tissue RNA - testis [nTPM]":"83.8","Tissue RNA - thalamus [nTPM]":"3.6","Tissue RNA - thymus [nTPM]":"5.2","Tissue RNA - thyroid gland [nTPM]":"16.5","Tissue RNA - tongue [nTPM]":"49.9","Tissue RNA - tonsil [nTPM]":"2.5","Tissue RNA - urinary bladder [nTPM]":"11.4","Tissue RNA - vagina [nTPM]":"10.5","Tissue RNA - white matter [nTPM]":"3.0","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"9.3","Cell RNA - AF22 [nTPM]":"8.8","Cell RNA - AN3-CA [nTPM]":"6.2","Cell RNA - ASC diff [nTPM]":"4.9","Cell RNA - ASC TERT1 [nTPM]":"4.6","Cell RNA - BEWO [nTPM]":"0.7","Cell RNA - BJ [nTPM]":"2.9","Cell RNA - BJ hTERT+ [nTPM]":"1.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.3","Cell RNA - CACO-2 [nTPM]":"0.9","Cell RNA - CAPAN-2 [nTPM]":"3.6","Cell RNA - Daudi [nTPM]":"1.4","Cell RNA - EFO-21 [nTPM]":"11.0","Cell RNA - fHDF\/TERT166 [nTPM]":"3.4","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"3.2","Cell RNA - HAP1 [nTPM]":"1.3","Cell RNA - HBEC3-KT [nTPM]":"2.0","Cell RNA - HBF TERT88 [nTPM]":"2.3","Cell RNA - HDLM-2 [nTPM]":"5.4","Cell RNA - HEK 293 [nTPM]":"7.8","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"5.9","Cell RNA - Hep G2 [nTPM]":"0.9","Cell RNA - HHSteC [nTPM]":"4.1","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"1.9","Cell RNA - HSkMC [nTPM]":"6.2","Cell RNA - hTCEpi [nTPM]":"1.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.8","Cell RNA - hTERT-HME1 [nTPM]":"2.9","Cell RNA - hTERT-RPE1 [nTPM]":"8.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.6","Cell RNA - JURKAT [nTPM]":"3.5","Cell RNA - K-562 [nTPM]":"1.5","Cell RNA - Karpas-707 [nTPM]":"2.0","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"4.7","Cell RNA - MOLT-4 [nTPM]":"2.1","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"2.2","Cell RNA - OE19 [nTPM]":"2.7","Cell RNA - PC-3 [nTPM]":"2.1","Cell RNA - REH [nTPM]":"1.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"5.7","Cell RNA - RT4 [nTPM]":"2.2","Cell RNA - SCLC-21H [nTPM]":"12.7","Cell RNA - SH-SY5Y [nTPM]":"14.5","Cell RNA - SiHa [nTPM]":"4.5","Cell RNA - SK-BR-3 [nTPM]":"4.4","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"4.6","Cell RNA - T-47d [nTPM]":"4.4","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"4.5","Cell RNA - U-138 MG [nTPM]":"1.1","Cell RNA - U-2 OS [nTPM]":"2.0","Cell RNA - U-2197 [nTPM]":"1.0","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"3.2","Cell RNA - U-266\/84 [nTPM]":"1.1","Cell RNA - U-698 [nTPM]":"1.0","Cell RNA - U-87 MG [nTPM]":"7.4","Cell RNA - U-937 [nTPM]":"0.9","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"1.6","Blood RNA - eosinophil [nTPM]":"1.8","Blood RNA - gdT-cell [nTPM]":"3.0","Blood RNA - intermediate monocyte [nTPM]":"1.7","Blood RNA - MAIT T-cell [nTPM]":"3.6","Blood RNA - memory B-cell [nTPM]":"2.4","Blood RNA - memory CD4 T-cell [nTPM]":"2.0","Blood RNA - memory CD8 T-cell [nTPM]":"3.1","Blood RNA - myeloid DC [nTPM]":"1.9","Blood RNA - naive B-cell [nTPM]":"1.6","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.7","Blood RNA - neutrophil [nTPM]":"2.5","Blood RNA - NK-cell [nTPM]":"3.3","Blood RNA - non-classical monocyte [nTPM]":"1.6","Blood RNA - plasmacytoid DC [nTPM]":"4.5","Blood RNA - T-reg [nTPM]":"2.2","Blood RNA - total PBMC [nTPM]":"1.7","Brain RNA - amygdala [nTPM]":"4.8","Brain RNA - basal ganglia [nTPM]":"4.8","Brain RNA - cerebellum [nTPM]":"4.1","Brain RNA - cerebral cortex [nTPM]":"6.2","Brain RNA - hippocampal formation [nTPM]":"4.7","Brain RNA - hypothalamus [nTPM]":"3.6","Brain RNA - medulla oblongata [nTPM]":"3.5","Brain RNA - midbrain [nTPM]":"3.4","Brain RNA - pons [nTPM]":"3.6","Brain RNA - spinal cord [nTPM]":"1.2","Brain RNA - thalamus [nTPM]":"3.6","Brain RNA - white matter [nTPM]":"3.0","Single Cell Type RNA - Adipocytes [nTPM]":"6.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"6.2","Single Cell Type RNA - B-cells [nTPM]":"10.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"15.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"3.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.1","Single Cell Type RNA - dendritic cells [nTPM]":"21.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"13.1","Single Cell Type RNA - Early spermatids [nTPM]":"179.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.7","Single Cell Type RNA - Endothelial cells [nTPM]":"7.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.4","Single Cell Type RNA - Erythroid cells [nTPM]":"19.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.7","Single Cell Type RNA - Fibroblasts [nTPM]":"5.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"11.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.1","Single Cell Type RNA - Hepatocytes [nTPM]":"3.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.9","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.8","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"8.2","Single Cell Type RNA - Langerhans cells [nTPM]":"3.0","Single Cell Type RNA - Late spermatids [nTPM]":"580.2","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"4.7","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"5.7","Single Cell Type RNA - Muller glia cells [nTPM]":"8.3","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.7","Single Cell Type RNA - Paneth cells [nTPM]":"9.7","Single Cell Type RNA - Peritubular cells [nTPM]":"5.3","Single Cell Type RNA - Plasma cells [nTPM]":"5.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.8","Single Cell Type RNA - Spermatocytes [nTPM]":"30.1","Single Cell Type RNA - Spermatogonia [nTPM]":"13.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - T-cells [nTPM]":"10.8","Single Cell Type RNA - Theca cells [nTPM]":"20.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.4","Single Cell Type RNA - Urothelial cells [nTPM]":"3.6"},{"Gene":"DYSF","Gene synonym":["FER1L1","LGMD2B"],"Ensembl":"ENSG00000135636","Gene description":"Dysferlin","Uniprot":["O75923"],"Chromosome":"2","Position":"71453722-71686768","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Limb-girdle muscular dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"95.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"30.5","Endothelial cells":"43.7","Excitatory neurons":"34.7","Hepatic stellate cells":"32.2","Kupffer cells":"27.1","Oligodendrocytes":"62.7","Syncytiotrophoblasts":"66.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"neutrophil":"27.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"27.0"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"hTERT-RPE1":"31.9","HUVEC TERT2":"85.5","LHCN-M2":"75.3","RH-30":"78.5","TIME":"58.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002510","HPA017071","HPA021945"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Centriolar satellite"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane","Centriolar satellite"],"Subcellular additional location":null,"Antibody RRID":{"CAB002510":"AB_442097","HPA017071":"AB_1847927","HPA021945":"AB_1847928"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-3"},"Tissue RNA - adipose tissue [nTPM]":"10.1","Tissue RNA - adrenal gland [nTPM]":"1.7","Tissue RNA - amygdala [nTPM]":"1.0","Tissue RNA - appendix [nTPM]":"11.5","Tissue RNA - basal ganglia [nTPM]":"1.1","Tissue RNA - bone marrow [nTPM]":"31.6","Tissue RNA - breast [nTPM]":"4.3","Tissue RNA - cerebellum [nTPM]":"4.1","Tissue RNA - cerebral cortex [nTPM]":"7.7","Tissue RNA - cervix [nTPM]":"1.9","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"7.0","Tissue RNA - duodenum [nTPM]":"2.0","Tissue RNA - endometrium 1 [nTPM]":"2.3","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"7.4","Tissue RNA - fallopian tube [nTPM]":"3.2","Tissue RNA - gallbladder [nTPM]":"4.6","Tissue RNA - heart muscle [nTPM]":"16.8","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"3.8","Tissue RNA - kidney [nTPM]":"3.6","Tissue RNA - liver [nTPM]":"6.5","Tissue RNA - lung [nTPM]":"8.3","Tissue RNA - lymph node [nTPM]":"3.7","Tissue RNA - medulla oblongata [nTPM]":"14.8","Tissue RNA - midbrain [nTPM]":"5.1","Tissue RNA - ovary [nTPM]":"1.3","Tissue RNA - pancreas [nTPM]":"1.5","Tissue RNA - parathyroid gland [nTPM]":"2.3","Tissue RNA - pituitary gland [nTPM]":"1.5","Tissue RNA - placenta [nTPM]":"21.1","Tissue RNA - pons [nTPM]":"13.7","Tissue RNA - prostate [nTPM]":"3.3","Tissue RNA - rectum [nTPM]":"2.5","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"1.3","Tissue RNA - seminal vesicle [nTPM]":"4.8","Tissue RNA - skeletal muscle [nTPM]":"95.3","Tissue RNA - skin 1 [nTPM]":"1.2","Tissue RNA - small intestine [nTPM]":"3.1","Tissue RNA - smooth muscle [nTPM]":"10.2","Tissue RNA - spinal cord [nTPM]":"2.0","Tissue RNA - spleen [nTPM]":"21.4","Tissue RNA - stomach 1 [nTPM]":"2.5","Tissue RNA - testis [nTPM]":"1.1","Tissue RNA - thalamus [nTPM]":"10.2","Tissue RNA - thymus [nTPM]":"2.3","Tissue RNA - thyroid gland [nTPM]":"4.6","Tissue RNA - tongue [nTPM]":"32.3","Tissue RNA - tonsil [nTPM]":"0.9","Tissue RNA - urinary bladder [nTPM]":"6.9","Tissue RNA - vagina [nTPM]":"1.8","Tissue RNA - white matter [nTPM]":"1.8","Cell RNA - A-431 [nTPM]":"1.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"3.3","Cell RNA - AN3-CA [nTPM]":"3.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"6.1","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.5","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"1.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"12.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"3.4","Cell RNA - HaCaT [nTPM]":"2.5","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"1.2","Cell RNA - HBF TERT88 [nTPM]":"1.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"1.5","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.3","Cell RNA - hTERT-HME1 [nTPM]":"10.6","Cell RNA - hTERT-RPE1 [nTPM]":"31.9","Cell RNA - HUVEC TERT2 [nTPM]":"85.5","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"8.4","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"75.3","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"5.8","Cell RNA - NTERA-2 [nTPM]":"8.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.9","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"78.5","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"2.6","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"4.1","Cell RNA - SK-BR-3 [nTPM]":"0.7","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"7.9","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.8","Cell RNA - TIME [nTPM]":"58.1","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"3.8","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"1.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"13.3","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"4.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"27.0","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"1.0","Brain RNA - basal ganglia [nTPM]":"1.1","Brain RNA - cerebellum [nTPM]":"4.1","Brain RNA - cerebral cortex [nTPM]":"7.7","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"3.8","Brain RNA - medulla oblongata [nTPM]":"14.8","Brain RNA - midbrain [nTPM]":"5.1","Brain RNA - pons [nTPM]":"13.7","Brain RNA - spinal cord [nTPM]":"2.0","Brain RNA - thalamus [nTPM]":"10.2","Brain RNA - white matter [nTPM]":"1.8","Single Cell Type RNA - Adipocytes [nTPM]":"30.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.1","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"24.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"4.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.3","Single Cell Type RNA - Endothelial cells [nTPM]":"43.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"34.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.8","Single Cell Type RNA - Fibroblasts [nTPM]":"2.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.3","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.2","Single Cell Type RNA - Hepatocytes [nTPM]":"13.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"27.1","Single Cell Type RNA - Langerhans cells [nTPM]":"3.0","Single Cell Type RNA - Late spermatids [nTPM]":"6.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"10.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"5.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"62.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"1.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"66.2","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"0.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"EARS2","Gene synonym":["KIAA1970","MSE1","mtGlnRS"],"Ensembl":"ENSG00000103356","Gene description":"Glutamyl-tRNA synthetase 2, mitochondrial","Uniprot":["Q5JPH6"],"Chromosome":"16","Position":"23520754-23557731","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase","RNA-binding"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043289","HPA043633"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA043289":"AB_10963932","HPA043633":"AB_10959901"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.20e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.16e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.7","Tissue RNA - adrenal gland [nTPM]":"7.6","Tissue RNA - amygdala [nTPM]":"3.3","Tissue RNA - appendix [nTPM]":"1.2","Tissue RNA - basal ganglia [nTPM]":"3.5","Tissue RNA - bone marrow [nTPM]":"1.5","Tissue RNA - breast [nTPM]":"4.0","Tissue RNA - cerebellum [nTPM]":"2.7","Tissue RNA - cerebral cortex [nTPM]":"4.0","Tissue RNA - cervix [nTPM]":"2.9","Tissue RNA - choroid plexus [nTPM]":"3.6","Tissue RNA - colon [nTPM]":"3.7","Tissue RNA - duodenum [nTPM]":"1.1","Tissue RNA - endometrium 1 [nTPM]":"3.7","Tissue RNA - epididymis [nTPM]":"3.0","Tissue RNA - esophagus [nTPM]":"5.2","Tissue RNA - fallopian tube [nTPM]":"3.0","Tissue RNA - gallbladder [nTPM]":"1.0","Tissue RNA - heart muscle [nTPM]":"5.3","Tissue RNA - hippocampal formation [nTPM]":"3.3","Tissue RNA - hypothalamus [nTPM]":"3.6","Tissue RNA - kidney [nTPM]":"4.9","Tissue RNA - liver [nTPM]":"9.9","Tissue RNA - lung [nTPM]":"3.1","Tissue RNA - lymph node [nTPM]":"1.8","Tissue RNA - medulla oblongata [nTPM]":"3.3","Tissue RNA - midbrain [nTPM]":"2.5","Tissue RNA - ovary [nTPM]":"3.3","Tissue RNA - pancreas [nTPM]":"5.6","Tissue RNA - parathyroid gland [nTPM]":"4.8","Tissue RNA - pituitary gland [nTPM]":"3.5","Tissue RNA - placenta [nTPM]":"2.5","Tissue RNA - pons [nTPM]":"2.6","Tissue RNA - prostate [nTPM]":"3.0","Tissue RNA - rectum [nTPM]":"2.3","Tissue RNA - retina [nTPM]":"1.9","Tissue RNA - salivary gland [nTPM]":"4.6","Tissue RNA - seminal vesicle [nTPM]":"1.4","Tissue RNA - skeletal muscle [nTPM]":"4.2","Tissue RNA - skin 1 [nTPM]":"5.6","Tissue RNA - small intestine [nTPM]":"2.9","Tissue RNA - smooth muscle [nTPM]":"2.0","Tissue RNA - spinal cord [nTPM]":"1.5","Tissue RNA - spleen [nTPM]":"3.3","Tissue RNA - stomach 1 [nTPM]":"4.1","Tissue RNA - testis [nTPM]":"3.8","Tissue RNA - thalamus [nTPM]":"3.5","Tissue RNA - thymus [nTPM]":"2.5","Tissue RNA - thyroid gland [nTPM]":"4.3","Tissue RNA - tongue [nTPM]":"3.8","Tissue RNA - tonsil [nTPM]":"2.4","Tissue RNA - urinary bladder [nTPM]":"3.3","Tissue RNA - vagina [nTPM]":"3.3","Tissue RNA - white matter [nTPM]":"3.2","Cell RNA - A-431 [nTPM]":"2.6","Cell RNA - A549 [nTPM]":"8.3","Cell RNA - AF22 [nTPM]":"2.4","Cell RNA - AN3-CA [nTPM]":"4.8","Cell RNA - ASC diff [nTPM]":"2.9","Cell RNA - ASC TERT1 [nTPM]":"3.8","Cell RNA - BEWO [nTPM]":"3.9","Cell RNA - BJ [nTPM]":"3.2","Cell RNA - BJ hTERT+ [nTPM]":"3.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.4","Cell RNA - CACO-2 [nTPM]":"5.0","Cell RNA - CAPAN-2 [nTPM]":"2.9","Cell RNA - Daudi [nTPM]":"4.8","Cell RNA - EFO-21 [nTPM]":"2.6","Cell RNA - fHDF\/TERT166 [nTPM]":"3.3","Cell RNA - GAMG [nTPM]":"1.8","Cell RNA - HaCaT [nTPM]":"2.9","Cell RNA - HAP1 [nTPM]":"9.6","Cell RNA - HBEC3-KT [nTPM]":"6.4","Cell RNA - HBF TERT88 [nTPM]":"4.7","Cell RNA - HDLM-2 [nTPM]":"2.9","Cell RNA - HEK 293 [nTPM]":"7.7","Cell RNA - HEL [nTPM]":"2.4","Cell RNA - HeLa [nTPM]":"5.3","Cell RNA - Hep G2 [nTPM]":"7.1","Cell RNA - HHSteC [nTPM]":"2.4","Cell RNA - HL-60 [nTPM]":"3.4","Cell RNA - HMC-1 [nTPM]":"2.1","Cell RNA - HSkMC [nTPM]":"3.2","Cell RNA - hTCEpi [nTPM]":"4.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.4","Cell RNA - hTERT-HME1 [nTPM]":"4.7","Cell RNA - hTERT-RPE1 [nTPM]":"4.5","Cell RNA - HUVEC TERT2 [nTPM]":"1.4","Cell RNA - JURKAT [nTPM]":"5.2","Cell RNA - K-562 [nTPM]":"7.0","Cell RNA - Karpas-707 [nTPM]":"2.5","Cell RNA - LHCN-M2 [nTPM]":"2.6","Cell RNA - MCF7 [nTPM]":"5.5","Cell RNA - MOLT-4 [nTPM]":"2.1","Cell RNA - NB-4 [nTPM]":"2.3","Cell RNA - NTERA-2 [nTPM]":"7.5","Cell RNA - OE19 [nTPM]":"4.4","Cell RNA - PC-3 [nTPM]":"2.8","Cell RNA - REH [nTPM]":"4.1","Cell RNA - RH-30 [nTPM]":"4.5","Cell RNA - RPMI-8226 [nTPM]":"8.0","Cell RNA - RPTEC TERT1 [nTPM]":"5.5","Cell RNA - RT4 [nTPM]":"3.8","Cell RNA - SCLC-21H [nTPM]":"5.0","Cell RNA - SH-SY5Y [nTPM]":"4.1","Cell RNA - SiHa [nTPM]":"2.1","Cell RNA - SK-BR-3 [nTPM]":"5.0","Cell RNA - SK-MEL-30 [nTPM]":"2.7","Cell RNA - SuSa [nTPM]":"6.3","Cell RNA - T-47d [nTPM]":"5.9","Cell RNA - THP-1 [nTPM]":"3.0","Cell RNA - TIME [nTPM]":"2.3","Cell RNA - U-138 MG [nTPM]":"3.1","Cell RNA - U-2 OS [nTPM]":"2.1","Cell RNA - U-2197 [nTPM]":"3.1","Cell RNA - U-251 MG [nTPM]":"3.4","Cell RNA - U-266\/70 [nTPM]":"5.1","Cell RNA - U-266\/84 [nTPM]":"3.7","Cell RNA - U-698 [nTPM]":"3.4","Cell RNA - U-87 MG [nTPM]":"4.1","Cell RNA - U-937 [nTPM]":"4.0","Cell RNA - WM-115 [nTPM]":"4.3","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.8","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"1.6","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.4","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"1.7","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"1.1","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"1.1","Blood RNA - plasmacytoid DC [nTPM]":"1.6","Blood RNA - T-reg [nTPM]":"1.7","Blood RNA - total PBMC [nTPM]":"1.3","Brain RNA - amygdala [nTPM]":"3.3","Brain RNA - basal ganglia [nTPM]":"3.5","Brain RNA - cerebellum [nTPM]":"2.7","Brain RNA - cerebral cortex [nTPM]":"4.0","Brain RNA - hippocampal formation [nTPM]":"3.3","Brain RNA - hypothalamus [nTPM]":"3.6","Brain RNA - medulla oblongata [nTPM]":"3.3","Brain RNA - midbrain [nTPM]":"2.5","Brain RNA - pons [nTPM]":"2.6","Brain RNA - spinal cord [nTPM]":"1.5","Brain RNA - thalamus [nTPM]":"3.5","Brain RNA - white matter [nTPM]":"3.2","Single Cell Type RNA - Adipocytes [nTPM]":"1.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.9","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"3.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"3.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"2.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.1","Single Cell Type RNA - dendritic cells [nTPM]":"2.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.9","Single Cell Type RNA - Endothelial cells [nTPM]":"3.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"9.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.3","Single Cell Type RNA - Fibroblasts [nTPM]":"4.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.4","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"6.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"11.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.1","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.3","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.2","Single Cell Type RNA - Langerhans cells [nTPM]":"2.5","Single Cell Type RNA - Late spermatids [nTPM]":"2.5","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"3.4","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"5.3","Single Cell Type RNA - Muller glia cells [nTPM]":"2.6","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.7","Single Cell Type RNA - Paneth cells [nTPM]":"1.7","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"8.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.4","Single Cell Type RNA - Spermatocytes [nTPM]":"5.8","Single Cell Type RNA - Spermatogonia [nTPM]":"9.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.4","Single Cell Type RNA - T-cells [nTPM]":"3.3","Single Cell Type RNA - Theca cells [nTPM]":"12.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.2","Single Cell Type RNA - Urothelial cells [nTPM]":"3.2"},{"Gene":"EBP","Gene synonym":["CDPX2","CHO2","CPX","CPXD"],"Ensembl":"ENSG00000147155","Gene description":"EBP cholestenol delta-isomerase","Uniprot":["Q15125"],"Chromosome":"X","Position":"48521799-48528716","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Isomerase"],"Disease involvement":["Cataract","Disease variant","Dwarfism","Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"328.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"674.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003130"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA003130":"AB_1078717"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.2","Tissue RNA - adrenal gland [nTPM]":"73.3","Tissue RNA - amygdala [nTPM]":"16.7","Tissue RNA - appendix [nTPM]":"17.1","Tissue RNA - basal ganglia [nTPM]":"17.2","Tissue RNA - bone marrow [nTPM]":"48.3","Tissue RNA - breast [nTPM]":"17.4","Tissue RNA - cerebellum [nTPM]":"18.5","Tissue RNA - cerebral cortex [nTPM]":"17.8","Tissue RNA - cervix [nTPM]":"19.4","Tissue RNA - choroid plexus [nTPM]":"22.0","Tissue RNA - colon [nTPM]":"50.6","Tissue RNA - duodenum [nTPM]":"85.5","Tissue RNA - endometrium 1 [nTPM]":"11.0","Tissue RNA - epididymis [nTPM]":"17.3","Tissue RNA - esophagus [nTPM]":"41.3","Tissue RNA - fallopian tube [nTPM]":"14.3","Tissue RNA - gallbladder [nTPM]":"10.5","Tissue RNA - heart muscle [nTPM]":"32.5","Tissue RNA - hippocampal formation [nTPM]":"16.8","Tissue RNA - hypothalamus [nTPM]":"18.7","Tissue RNA - kidney [nTPM]":"44.0","Tissue RNA - liver [nTPM]":"328.5","Tissue RNA - lung [nTPM]":"24.4","Tissue RNA - lymph node [nTPM]":"18.8","Tissue RNA - medulla oblongata [nTPM]":"24.4","Tissue RNA - midbrain [nTPM]":"16.6","Tissue RNA - ovary [nTPM]":"12.7","Tissue RNA - pancreas [nTPM]":"26.0","Tissue RNA - parathyroid gland [nTPM]":"44.0","Tissue RNA - pituitary gland [nTPM]":"7.2","Tissue RNA - placenta [nTPM]":"8.2","Tissue RNA - pons [nTPM]":"24.2","Tissue RNA - prostate [nTPM]":"40.6","Tissue RNA - rectum [nTPM]":"57.5","Tissue RNA - retina [nTPM]":"10.7","Tissue RNA - salivary gland [nTPM]":"25.0","Tissue RNA - seminal vesicle [nTPM]":"11.7","Tissue RNA - skeletal muscle [nTPM]":"9.5","Tissue RNA - skin 1 [nTPM]":"27.8","Tissue RNA - small intestine [nTPM]":"54.2","Tissue RNA - smooth muscle [nTPM]":"14.9","Tissue RNA - spinal cord [nTPM]":"15.8","Tissue RNA - spleen [nTPM]":"16.9","Tissue RNA - stomach 1 [nTPM]":"31.6","Tissue RNA - testis [nTPM]":"14.2","Tissue RNA - thalamus [nTPM]":"15.9","Tissue RNA - thymus [nTPM]":"28.2","Tissue RNA - thyroid gland [nTPM]":"14.4","Tissue RNA - tongue [nTPM]":"10.6","Tissue RNA - tonsil [nTPM]":"32.7","Tissue RNA - urinary bladder [nTPM]":"14.1","Tissue RNA - vagina [nTPM]":"23.3","Tissue RNA - white matter [nTPM]":"16.0","Cell RNA - A-431 [nTPM]":"224.5","Cell RNA - A549 [nTPM]":"96.4","Cell RNA - AF22 [nTPM]":"107.4","Cell RNA - AN3-CA [nTPM]":"77.0","Cell RNA - ASC diff [nTPM]":"74.5","Cell RNA - ASC TERT1 [nTPM]":"39.2","Cell RNA - BEWO [nTPM]":"50.5","Cell RNA - BJ [nTPM]":"48.2","Cell RNA - BJ hTERT+ [nTPM]":"43.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"64.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"93.9","Cell RNA - CACO-2 [nTPM]":"169.9","Cell RNA - CAPAN-2 [nTPM]":"382.7","Cell RNA - Daudi [nTPM]":"115.9","Cell RNA - EFO-21 [nTPM]":"35.2","Cell RNA - fHDF\/TERT166 [nTPM]":"41.3","Cell RNA - GAMG [nTPM]":"83.5","Cell RNA - HaCaT [nTPM]":"230.3","Cell RNA - HAP1 [nTPM]":"217.5","Cell RNA - HBEC3-KT [nTPM]":"293.8","Cell RNA - HBF TERT88 [nTPM]":"49.8","Cell RNA - HDLM-2 [nTPM]":"85.8","Cell RNA - HEK 293 [nTPM]":"149.7","Cell RNA - HEL [nTPM]":"50.1","Cell RNA - HeLa [nTPM]":"115.2","Cell RNA - Hep G2 [nTPM]":"139.3","Cell RNA - HHSteC [nTPM]":"57.8","Cell RNA - HL-60 [nTPM]":"179.2","Cell RNA - HMC-1 [nTPM]":"138.2","Cell RNA - HSkMC [nTPM]":"51.3","Cell RNA - hTCEpi [nTPM]":"108.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"112.9","Cell RNA - hTERT-HME1 [nTPM]":"86.4","Cell RNA - hTERT-RPE1 [nTPM]":"22.5","Cell RNA - HUVEC TERT2 [nTPM]":"46.5","Cell RNA - JURKAT [nTPM]":"98.1","Cell RNA - K-562 [nTPM]":"77.6","Cell RNA - Karpas-707 [nTPM]":"119.5","Cell RNA - LHCN-M2 [nTPM]":"50.7","Cell RNA - MCF7 [nTPM]":"163.7","Cell RNA - MOLT-4 [nTPM]":"119.1","Cell RNA - NB-4 [nTPM]":"199.9","Cell RNA - NTERA-2 [nTPM]":"118.2","Cell RNA - OE19 [nTPM]":"88.3","Cell RNA - PC-3 [nTPM]":"199.1","Cell RNA - REH [nTPM]":"93.8","Cell RNA - RH-30 [nTPM]":"10.3","Cell RNA - RPMI-8226 [nTPM]":"363.7","Cell RNA - RPTEC TERT1 [nTPM]":"175.6","Cell RNA - RT4 [nTPM]":"68.8","Cell RNA - SCLC-21H [nTPM]":"110.0","Cell RNA - SH-SY5Y [nTPM]":"59.6","Cell RNA - SiHa [nTPM]":"175.4","Cell RNA - SK-BR-3 [nTPM]":"122.6","Cell RNA - SK-MEL-30 [nTPM]":"31.2","Cell RNA - SuSa [nTPM]":"91.5","Cell RNA - T-47d [nTPM]":"122.9","Cell RNA - THP-1 [nTPM]":"71.1","Cell RNA - TIME [nTPM]":"46.6","Cell RNA - U-138 MG [nTPM]":"33.1","Cell RNA - U-2 OS [nTPM]":"56.2","Cell RNA - U-2197 [nTPM]":"132.9","Cell RNA - U-251 MG [nTPM]":"63.1","Cell RNA - U-266\/70 [nTPM]":"47.5","Cell RNA - U-266\/84 [nTPM]":"72.1","Cell RNA - U-698 [nTPM]":"107.7","Cell RNA - U-87 MG [nTPM]":"78.7","Cell RNA - U-937 [nTPM]":"239.7","Cell RNA - WM-115 [nTPM]":"40.6","Blood RNA - basophil [nTPM]":"96.1","Blood RNA - classical monocyte [nTPM]":"37.7","Blood RNA - eosinophil [nTPM]":"97.1","Blood RNA - gdT-cell [nTPM]":"129.4","Blood RNA - intermediate monocyte [nTPM]":"53.4","Blood RNA - MAIT T-cell [nTPM]":"104.5","Blood RNA - memory B-cell [nTPM]":"71.5","Blood RNA - memory CD4 T-cell [nTPM]":"90.5","Blood RNA - memory CD8 T-cell [nTPM]":"116.7","Blood RNA - myeloid DC [nTPM]":"53.5","Blood RNA - naive B-cell [nTPM]":"57.2","Blood RNA - naive CD4 T-cell [nTPM]":"76.5","Blood RNA - naive CD8 T-cell [nTPM]":"99.7","Blood RNA - neutrophil [nTPM]":"7.3","Blood RNA - NK-cell [nTPM]":"63.9","Blood RNA - non-classical monocyte [nTPM]":"57.2","Blood RNA - plasmacytoid DC [nTPM]":"105.4","Blood RNA - T-reg [nTPM]":"103.1","Blood RNA - total PBMC [nTPM]":"93.6","Brain RNA - amygdala [nTPM]":"16.7","Brain RNA - basal ganglia [nTPM]":"17.2","Brain RNA - cerebellum [nTPM]":"18.5","Brain RNA - cerebral cortex [nTPM]":"17.8","Brain RNA - hippocampal formation [nTPM]":"16.8","Brain RNA - hypothalamus [nTPM]":"18.7","Brain RNA - medulla oblongata [nTPM]":"24.4","Brain RNA - midbrain [nTPM]":"16.6","Brain RNA - pons [nTPM]":"24.2","Brain RNA - spinal cord [nTPM]":"15.8","Brain RNA - thalamus [nTPM]":"15.9","Brain RNA - white matter [nTPM]":"16.0","Single Cell Type RNA - Adipocytes [nTPM]":"15.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"49.8","Single Cell Type RNA - Astrocytes [nTPM]":"2.9","Single Cell Type RNA - B-cells [nTPM]":"38.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"37.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"58.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"245.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.3","Single Cell Type RNA - Bipolar cells [nTPM]":"23.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"57.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"26.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"49.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"77.2","Single Cell Type RNA - Club cells [nTPM]":"116.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"53.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"55.9","Single Cell Type RNA - dendritic cells [nTPM]":"74.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"140.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"39.2","Single Cell Type RNA - Ductal cells [nTPM]":"91.7","Single Cell Type RNA - Early spermatids [nTPM]":"10.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"30.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.7","Single Cell Type RNA - Endothelial cells [nTPM]":"26.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"30.0","Single Cell Type RNA - Erythroid cells [nTPM]":"48.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"239.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"113.0","Single Cell Type RNA - Fibroblasts [nTPM]":"21.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"36.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"56.5","Single Cell Type RNA - granulocytes [nTPM]":"40.6","Single Cell Type RNA - Granulosa cells [nTPM]":"41.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"27.1","Single Cell Type RNA - Hepatocytes [nTPM]":"674.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"65.0","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"96.8","Single Cell Type RNA - Ionocytes [nTPM]":"93.6","Single Cell Type RNA - Kupffer cells [nTPM]":"30.2","Single Cell Type RNA - Langerhans cells [nTPM]":"36.0","Single Cell Type RNA - Late spermatids [nTPM]":"11.8","Single Cell Type RNA - Leydig cells [nTPM]":"13.4","Single Cell Type RNA - Macrophages [nTPM]":"31.9","Single Cell Type RNA - Melanocytes [nTPM]":"37.4","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"34.8","Single Cell Type RNA - Muller glia cells [nTPM]":"19.3","Single Cell Type RNA - NK-cells [nTPM]":"101.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"156.7","Single Cell Type RNA - Paneth cells [nTPM]":"137.3","Single Cell Type RNA - Peritubular cells [nTPM]":"14.7","Single Cell Type RNA - Plasma cells [nTPM]":"54.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"46.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"171.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"99.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"34.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.3","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.6","Single Cell Type RNA - Spermatocytes [nTPM]":"8.7","Single Cell Type RNA - Spermatogonia [nTPM]":"22.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"47.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"45.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"37.5","Single Cell Type RNA - T-cells [nTPM]":"57.1","Single Cell Type RNA - Theca cells [nTPM]":"128.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"149.1","Single Cell Type RNA - Urothelial cells [nTPM]":"71.1"},{"Gene":"ECE1","Gene synonym":["ECE"],"Ensembl":"ENSG00000117298","Gene description":"Endothelin converting enzyme 1","Uniprot":["P42892"],"Chromosome":"1","Position":"21217247-21345572","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant","Hirschsprung disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"164.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"29.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HUVEC TERT2":"673.8","TIME":"588.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001490","HPA013616"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1300000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA001490":"AB_1078718","HPA013616":"AB_1847963"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Tissue RNA - adipose tissue [nTPM]":"87.3","Tissue RNA - adrenal gland [nTPM]":"123.2","Tissue RNA - amygdala [nTPM]":"26.5","Tissue RNA - appendix [nTPM]":"47.7","Tissue RNA - basal ganglia [nTPM]":"29.4","Tissue RNA - bone marrow [nTPM]":"48.1","Tissue RNA - breast [nTPM]":"79.4","Tissue RNA - cerebellum [nTPM]":"23.0","Tissue RNA - cerebral cortex [nTPM]":"30.1","Tissue RNA - cervix [nTPM]":"61.4","Tissue RNA - choroid plexus [nTPM]":"12.6","Tissue RNA - colon [nTPM]":"71.0","Tissue RNA - duodenum [nTPM]":"30.1","Tissue RNA - endometrium 1 [nTPM]":"42.4","Tissue RNA - epididymis [nTPM]":"10.0","Tissue RNA - esophagus [nTPM]":"26.7","Tissue RNA - fallopian tube [nTPM]":"46.9","Tissue RNA - gallbladder [nTPM]":"36.8","Tissue RNA - heart muscle [nTPM]":"70.9","Tissue RNA - hippocampal formation [nTPM]":"21.3","Tissue RNA - hypothalamus [nTPM]":"33.7","Tissue RNA - kidney [nTPM]":"38.1","Tissue RNA - liver [nTPM]":"54.0","Tissue RNA - lung [nTPM]":"72.1","Tissue RNA - lymph node [nTPM]":"35.7","Tissue RNA - medulla oblongata [nTPM]":"34.4","Tissue RNA - midbrain [nTPM]":"25.7","Tissue RNA - ovary [nTPM]":"71.0","Tissue RNA - pancreas [nTPM]":"91.8","Tissue RNA - parathyroid gland [nTPM]":"125.0","Tissue RNA - pituitary gland [nTPM]":"47.4","Tissue RNA - placenta [nTPM]":"66.5","Tissue RNA - pons [nTPM]":"30.4","Tissue RNA - prostate [nTPM]":"53.1","Tissue RNA - rectum [nTPM]":"34.7","Tissue RNA - retina [nTPM]":"14.7","Tissue RNA - salivary gland [nTPM]":"33.6","Tissue RNA - seminal vesicle [nTPM]":"25.1","Tissue RNA - skeletal muscle [nTPM]":"19.8","Tissue RNA - skin 1 [nTPM]":"34.3","Tissue RNA - small intestine [nTPM]":"46.1","Tissue RNA - smooth muscle [nTPM]":"42.3","Tissue RNA - spinal cord [nTPM]":"21.2","Tissue RNA - spleen [nTPM]":"48.5","Tissue RNA - stomach 1 [nTPM]":"43.3","Tissue RNA - testis [nTPM]":"22.7","Tissue RNA - thalamus [nTPM]":"28.1","Tissue RNA - thymus [nTPM]":"21.1","Tissue RNA - thyroid gland [nTPM]":"51.4","Tissue RNA - tongue [nTPM]":"33.2","Tissue RNA - tonsil [nTPM]":"34.9","Tissue RNA - urinary bladder [nTPM]":"58.8","Tissue RNA - vagina [nTPM]":"43.8","Tissue RNA - white matter [nTPM]":"27.5","Cell RNA - A-431 [nTPM]":"93.0","Cell RNA - A549 [nTPM]":"60.1","Cell RNA - AF22 [nTPM]":"77.9","Cell RNA - AN3-CA [nTPM]":"38.3","Cell RNA - ASC diff [nTPM]":"111.0","Cell RNA - ASC TERT1 [nTPM]":"116.4","Cell RNA - BEWO [nTPM]":"44.1","Cell RNA - BJ [nTPM]":"135.4","Cell RNA - BJ hTERT+ [nTPM]":"236.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"72.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"66.6","Cell RNA - CACO-2 [nTPM]":"44.1","Cell RNA - CAPAN-2 [nTPM]":"275.8","Cell RNA - Daudi [nTPM]":"34.0","Cell RNA - EFO-21 [nTPM]":"323.6","Cell RNA - fHDF\/TERT166 [nTPM]":"138.8","Cell RNA - GAMG [nTPM]":"157.7","Cell RNA - HaCaT [nTPM]":"38.4","Cell RNA - HAP1 [nTPM]":"32.6","Cell RNA - HBEC3-KT [nTPM]":"64.9","Cell RNA - HBF TERT88 [nTPM]":"63.5","Cell RNA - HDLM-2 [nTPM]":"83.0","Cell RNA - HEK 293 [nTPM]":"27.2","Cell RNA - HEL [nTPM]":"48.7","Cell RNA - HeLa [nTPM]":"89.9","Cell RNA - Hep G2 [nTPM]":"34.8","Cell RNA - HHSteC [nTPM]":"144.3","Cell RNA - HL-60 [nTPM]":"7.1","Cell RNA - HMC-1 [nTPM]":"11.8","Cell RNA - HSkMC [nTPM]":"61.6","Cell RNA - hTCEpi [nTPM]":"74.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"112.6","Cell RNA - hTERT-HME1 [nTPM]":"55.8","Cell RNA - hTERT-RPE1 [nTPM]":"199.2","Cell RNA - HUVEC TERT2 [nTPM]":"673.8","Cell RNA - JURKAT [nTPM]":"27.6","Cell RNA - K-562 [nTPM]":"10.0","Cell RNA - Karpas-707 [nTPM]":"17.7","Cell RNA - LHCN-M2 [nTPM]":"62.9","Cell RNA - MCF7 [nTPM]":"19.4","Cell RNA - MOLT-4 [nTPM]":"14.6","Cell RNA - NB-4 [nTPM]":"11.4","Cell RNA - NTERA-2 [nTPM]":"23.2","Cell RNA - OE19 [nTPM]":"26.3","Cell RNA - PC-3 [nTPM]":"46.5","Cell RNA - REH [nTPM]":"17.5","Cell RNA - RH-30 [nTPM]":"45.0","Cell RNA - RPMI-8226 [nTPM]":"49.2","Cell RNA - RPTEC TERT1 [nTPM]":"114.0","Cell RNA - RT4 [nTPM]":"17.0","Cell RNA - SCLC-21H [nTPM]":"26.4","Cell RNA - SH-SY5Y [nTPM]":"63.1","Cell RNA - SiHa [nTPM]":"134.3","Cell RNA - SK-BR-3 [nTPM]":"79.2","Cell RNA - SK-MEL-30 [nTPM]":"57.4","Cell RNA - SuSa [nTPM]":"42.5","Cell RNA - T-47d [nTPM]":"55.9","Cell RNA - THP-1 [nTPM]":"20.2","Cell RNA - TIME [nTPM]":"588.7","Cell RNA - U-138 MG [nTPM]":"160.7","Cell RNA - U-2 OS [nTPM]":"77.9","Cell RNA - U-2197 [nTPM]":"73.3","Cell RNA - U-251 MG [nTPM]":"79.9","Cell RNA - U-266\/70 [nTPM]":"26.4","Cell RNA - U-266\/84 [nTPM]":"49.0","Cell RNA - U-698 [nTPM]":"39.1","Cell RNA - U-87 MG [nTPM]":"332.6","Cell RNA - U-937 [nTPM]":"16.5","Cell RNA - WM-115 [nTPM]":"196.6","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"8.4","Blood RNA - eosinophil [nTPM]":"3.3","Blood RNA - gdT-cell [nTPM]":"2.9","Blood RNA - intermediate monocyte [nTPM]":"10.0","Blood RNA - MAIT T-cell [nTPM]":"4.2","Blood RNA - memory B-cell [nTPM]":"6.1","Blood RNA - memory CD4 T-cell [nTPM]":"6.1","Blood RNA - memory CD8 T-cell [nTPM]":"4.6","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"4.1","Blood RNA - naive CD4 T-cell [nTPM]":"4.0","Blood RNA - naive CD8 T-cell [nTPM]":"2.7","Blood RNA - neutrophil [nTPM]":"29.8","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"7.8","Blood RNA - plasmacytoid DC [nTPM]":"2.8","Blood RNA - T-reg [nTPM]":"8.6","Blood RNA - total PBMC [nTPM]":"7.2","Brain RNA - amygdala [nTPM]":"26.5","Brain RNA - basal ganglia [nTPM]":"29.4","Brain RNA - cerebellum [nTPM]":"23.0","Brain RNA - cerebral cortex [nTPM]":"30.1","Brain RNA - hippocampal formation [nTPM]":"21.3","Brain RNA - hypothalamus [nTPM]":"33.7","Brain RNA - medulla oblongata [nTPM]":"34.4","Brain RNA - midbrain [nTPM]":"25.7","Brain RNA - pons [nTPM]":"30.4","Brain RNA - spinal cord [nTPM]":"21.2","Brain RNA - thalamus [nTPM]":"28.1","Brain RNA - white matter [nTPM]":"27.5","Single Cell Type RNA - Adipocytes [nTPM]":"164.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.5","Single Cell Type RNA - Astrocytes [nTPM]":"46.4","Single Cell Type RNA - B-cells [nTPM]":"25.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"19.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"81.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Bipolar cells [nTPM]":"5.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"71.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"44.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"54.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.0","Single Cell Type RNA - dendritic cells [nTPM]":"12.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"105.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"25.8","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"35.2","Single Cell Type RNA - Endothelial cells [nTPM]":"106.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"25.2","Single Cell Type RNA - Erythroid cells [nTPM]":"20.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"56.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"35.0","Single Cell Type RNA - Fibroblasts [nTPM]":"51.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"51.8","Single Cell Type RNA - granulocytes [nTPM]":"18.4","Single Cell Type RNA - Granulosa cells [nTPM]":"35.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"97.1","Single Cell Type RNA - Hepatocytes [nTPM]":"36.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.0","Single Cell Type RNA - Ionocytes [nTPM]":"57.0","Single Cell Type RNA - Kupffer cells [nTPM]":"9.6","Single Cell Type RNA - Langerhans cells [nTPM]":"14.3","Single Cell Type RNA - Late spermatids [nTPM]":"4.2","Single Cell Type RNA - Leydig cells [nTPM]":"43.5","Single Cell Type RNA - Macrophages [nTPM]":"17.3","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"31.9","Single Cell Type RNA - monocytes [nTPM]":"25.5","Single Cell Type RNA - Muller glia cells [nTPM]":"50.4","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"22.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"100.4","Single Cell Type RNA - Paneth cells [nTPM]":"106.5","Single Cell Type RNA - Peritubular cells [nTPM]":"55.3","Single Cell Type RNA - Plasma cells [nTPM]":"29.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"34.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"45.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"24.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.4","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"72.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"47.5","Single Cell Type RNA - Spermatocytes [nTPM]":"1.3","Single Cell Type RNA - Spermatogonia [nTPM]":"5.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.5","Single Cell Type RNA - T-cells [nTPM]":"17.9","Single Cell Type RNA - Theca cells [nTPM]":"80.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"21.6","Single Cell Type RNA - Urothelial cells [nTPM]":"40.8"},{"Gene":"ECEL1","Gene synonym":["DINE","XCE"],"Ensembl":"ENSG00000171551","Gene description":"Endothelin converting enzyme like 1","Uniprot":["O95672"],"Chromosome":"2","Position":"232479827-232487834","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"106.9","ovary":"99.7","pituitary gland":"27.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"33.5","Muller glia cells":"100.3","Peritubular cells":"21.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"12.9"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"hypothalamus":"106.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"AN3-CA":"44.1","HeLa":"21.8"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hypothalamus":"70.7"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067560","HPA069756","HPA077424"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 23: AN3-CA - Transcription regulation","Single cell expression cluster":"Cluster 5: Muller glia cells - Visual perception","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear membrane","Nucleoli"],"Antibody RRID":{"HPA067560":null,"HPA069756":null,"HPA077424":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.96e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.8","Tissue RNA - adrenal gland [nTPM]":"10.0","Tissue RNA - amygdala [nTPM]":"5.2","Tissue RNA - appendix [nTPM]":"1.0","Tissue RNA - basal ganglia [nTPM]":"5.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.7","Tissue RNA - cerebellum [nTPM]":"1.2","Tissue RNA - cerebral cortex [nTPM]":"31.6","Tissue RNA - cervix [nTPM]":"1.0","Tissue RNA - choroid plexus [nTPM]":"3.4","Tissue RNA - colon [nTPM]":"0.8","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"2.2","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"3.5","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"106.9","Tissue RNA - kidney [nTPM]":"4.1","Tissue RNA - liver [nTPM]":"2.5","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"20.9","Tissue RNA - midbrain [nTPM]":"11.3","Tissue RNA - ovary [nTPM]":"99.7","Tissue RNA - pancreas [nTPM]":"0.7","Tissue RNA - parathyroid gland [nTPM]":"1.2","Tissue RNA - pituitary gland [nTPM]":"27.6","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"17.1","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"13.4","Tissue RNA - salivary gland [nTPM]":"0.6","Tissue RNA - seminal vesicle [nTPM]":"1.5","Tissue RNA - skeletal muscle [nTPM]":"3.0","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"1.4","Tissue RNA - spinal cord [nTPM]":"2.4","Tissue RNA - spleen [nTPM]":"4.5","Tissue RNA - stomach 1 [nTPM]":"0.9","Tissue RNA - testis [nTPM]":"1.9","Tissue RNA - thalamus [nTPM]":"44.2","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"1.4","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"1.1","Tissue RNA - white matter [nTPM]":"4.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"44.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"2.6","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.6","Cell RNA - EFO-21 [nTPM]":"0.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.6","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"4.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"21.8","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.8","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"3.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"5.7","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"5.2","Brain RNA - basal ganglia [nTPM]":"5.5","Brain RNA - cerebellum [nTPM]":"1.2","Brain RNA - cerebral cortex [nTPM]":"31.6","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"106.9","Brain RNA - medulla oblongata [nTPM]":"20.9","Brain RNA - midbrain [nTPM]":"11.3","Brain RNA - pons [nTPM]":"17.1","Brain RNA - spinal cord [nTPM]":"2.4","Brain RNA - thalamus [nTPM]":"44.2","Brain RNA - white matter [nTPM]":"4.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"33.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"4.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"100.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"21.1","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"EGLN1","Gene synonym":["C1orf12","HIFPH2","PHD2","SM-20","ZMYND6"],"Ensembl":"ENSG00000135766","Gene description":"Egl-9 family hypoxia inducible factor 1","Uniprot":["Q9GZT9"],"Chromosome":"1","Position":"231363751-231422287","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Dioxygenase","Oxidoreductase"],"Disease involvement":["Congenital erythrocytosis","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"190.7"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"neutrophil":"29.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"15","RNA blood lineage specific nTPM":{"granulocytes":"29.1"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022129"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA022129":"AB_1848046"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.99e-7"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Tissue RNA - adipose tissue [nTPM]":"32.8","Tissue RNA - adrenal gland [nTPM]":"35.6","Tissue RNA - amygdala [nTPM]":"37.5","Tissue RNA - appendix [nTPM]":"18.1","Tissue RNA - basal ganglia [nTPM]":"40.8","Tissue RNA - bone marrow [nTPM]":"20.0","Tissue RNA - breast [nTPM]":"23.9","Tissue RNA - cerebellum [nTPM]":"38.8","Tissue RNA - cerebral cortex [nTPM]":"43.2","Tissue RNA - cervix [nTPM]":"26.3","Tissue RNA - choroid plexus [nTPM]":"31.6","Tissue RNA - colon [nTPM]":"30.0","Tissue RNA - duodenum [nTPM]":"34.0","Tissue RNA - endometrium 1 [nTPM]":"30.8","Tissue RNA - epididymis [nTPM]":"24.5","Tissue RNA - esophagus [nTPM]":"33.6","Tissue RNA - fallopian tube [nTPM]":"24.2","Tissue RNA - gallbladder [nTPM]":"28.2","Tissue RNA - heart muscle [nTPM]":"58.7","Tissue RNA - hippocampal formation [nTPM]":"39.9","Tissue RNA - hypothalamus [nTPM]":"37.2","Tissue RNA - kidney [nTPM]":"38.8","Tissue RNA - liver [nTPM]":"56.5","Tissue RNA - lung [nTPM]":"19.1","Tissue RNA - lymph node [nTPM]":"21.1","Tissue RNA - medulla oblongata [nTPM]":"41.6","Tissue RNA - midbrain [nTPM]":"39.0","Tissue RNA - ovary [nTPM]":"37.5","Tissue RNA - pancreas [nTPM]":"40.0","Tissue RNA - parathyroid gland [nTPM]":"39.0","Tissue RNA - pituitary gland [nTPM]":"9.3","Tissue RNA - placenta [nTPM]":"42.6","Tissue RNA - pons [nTPM]":"36.8","Tissue RNA - prostate [nTPM]":"23.8","Tissue RNA - rectum [nTPM]":"26.1","Tissue RNA - retina [nTPM]":"49.9","Tissue RNA - salivary gland [nTPM]":"22.0","Tissue RNA - seminal vesicle [nTPM]":"30.3","Tissue RNA - skeletal muscle [nTPM]":"190.7","Tissue RNA - skin 1 [nTPM]":"48.6","Tissue RNA - small intestine [nTPM]":"35.5","Tissue RNA - smooth muscle [nTPM]":"27.6","Tissue RNA - spinal cord [nTPM]":"40.9","Tissue RNA - spleen [nTPM]":"27.6","Tissue RNA - stomach 1 [nTPM]":"19.1","Tissue RNA - testis [nTPM]":"17.1","Tissue RNA - thalamus [nTPM]":"43.4","Tissue RNA - thymus [nTPM]":"16.7","Tissue RNA - thyroid gland [nTPM]":"25.5","Tissue RNA - tongue [nTPM]":"153.4","Tissue RNA - tonsil [nTPM]":"21.3","Tissue RNA - urinary bladder [nTPM]":"27.0","Tissue RNA - vagina [nTPM]":"12.0","Tissue RNA - white matter [nTPM]":"40.9","Cell RNA - A-431 [nTPM]":"54.2","Cell RNA - A549 [nTPM]":"59.9","Cell RNA - AF22 [nTPM]":"17.5","Cell RNA - AN3-CA [nTPM]":"33.7","Cell RNA - ASC diff [nTPM]":"44.8","Cell RNA - ASC TERT1 [nTPM]":"29.4","Cell RNA - BEWO [nTPM]":"15.8","Cell RNA - BJ [nTPM]":"22.7","Cell RNA - BJ hTERT+ [nTPM]":"42.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"36.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"49.4","Cell RNA - CACO-2 [nTPM]":"41.3","Cell RNA - CAPAN-2 [nTPM]":"48.0","Cell RNA - Daudi [nTPM]":"15.5","Cell RNA - EFO-21 [nTPM]":"41.7","Cell RNA - fHDF\/TERT166 [nTPM]":"42.4","Cell RNA - GAMG [nTPM]":"31.7","Cell RNA - HaCaT [nTPM]":"25.1","Cell RNA - HAP1 [nTPM]":"26.8","Cell RNA - HBEC3-KT [nTPM]":"30.1","Cell RNA - HBF TERT88 [nTPM]":"61.0","Cell RNA - HDLM-2 [nTPM]":"18.6","Cell RNA - HEK 293 [nTPM]":"42.5","Cell RNA - HEL [nTPM]":"6.7","Cell RNA - HeLa [nTPM]":"23.5","Cell RNA - Hep G2 [nTPM]":"37.7","Cell RNA - HHSteC [nTPM]":"31.5","Cell RNA - HL-60 [nTPM]":"38.5","Cell RNA - HMC-1 [nTPM]":"8.1","Cell RNA - HSkMC [nTPM]":"25.4","Cell RNA - hTCEpi [nTPM]":"27.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"24.9","Cell RNA - hTERT-HME1 [nTPM]":"34.2","Cell RNA - hTERT-RPE1 [nTPM]":"58.6","Cell RNA - HUVEC TERT2 [nTPM]":"49.3","Cell RNA - JURKAT [nTPM]":"18.5","Cell RNA - K-562 [nTPM]":"33.9","Cell RNA - Karpas-707 [nTPM]":"37.9","Cell RNA - LHCN-M2 [nTPM]":"38.3","Cell RNA - MCF7 [nTPM]":"12.2","Cell RNA - MOLT-4 [nTPM]":"8.9","Cell RNA - NB-4 [nTPM]":"14.4","Cell RNA - NTERA-2 [nTPM]":"18.4","Cell RNA - OE19 [nTPM]":"33.4","Cell RNA - PC-3 [nTPM]":"21.0","Cell RNA - REH [nTPM]":"20.0","Cell RNA - RH-30 [nTPM]":"21.7","Cell RNA - RPMI-8226 [nTPM]":"22.7","Cell RNA - RPTEC TERT1 [nTPM]":"48.0","Cell RNA - RT4 [nTPM]":"23.4","Cell RNA - SCLC-21H [nTPM]":"15.9","Cell RNA - SH-SY5Y [nTPM]":"45.3","Cell RNA - SiHa [nTPM]":"32.9","Cell RNA - SK-BR-3 [nTPM]":"41.4","Cell RNA - SK-MEL-30 [nTPM]":"83.1","Cell RNA - SuSa [nTPM]":"11.2","Cell RNA - T-47d [nTPM]":"22.4","Cell RNA - THP-1 [nTPM]":"112.8","Cell RNA - TIME [nTPM]":"54.3","Cell RNA - U-138 MG [nTPM]":"44.3","Cell RNA - U-2 OS [nTPM]":"20.8","Cell RNA - U-2197 [nTPM]":"40.5","Cell RNA - U-251 MG [nTPM]":"47.2","Cell RNA - U-266\/70 [nTPM]":"65.7","Cell RNA - U-266\/84 [nTPM]":"46.4","Cell RNA - U-698 [nTPM]":"14.7","Cell RNA - U-87 MG [nTPM]":"60.4","Cell RNA - U-937 [nTPM]":"14.0","Cell RNA - WM-115 [nTPM]":"59.4","Blood RNA - basophil [nTPM]":"4.2","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"3.1","Blood RNA - gdT-cell [nTPM]":"1.2","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"0.8","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.8","Blood RNA - neutrophil [nTPM]":"29.1","Blood RNA - NK-cell [nTPM]":"1.6","Blood RNA - non-classical monocyte [nTPM]":"1.8","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"0.5","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"37.5","Brain RNA - basal ganglia [nTPM]":"40.8","Brain RNA - cerebellum [nTPM]":"38.8","Brain RNA - cerebral cortex [nTPM]":"43.2","Brain RNA - hippocampal formation [nTPM]":"39.9","Brain RNA - hypothalamus [nTPM]":"37.2","Brain RNA - medulla oblongata [nTPM]":"41.6","Brain RNA - midbrain [nTPM]":"39.0","Brain RNA - pons [nTPM]":"36.8","Brain RNA - spinal cord [nTPM]":"40.9","Brain RNA - thalamus [nTPM]":"43.4","Brain RNA - white matter [nTPM]":"40.9","Single Cell Type RNA - Adipocytes [nTPM]":"64.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.2","Single Cell Type RNA - Astrocytes [nTPM]":"36.6","Single Cell Type RNA - B-cells [nTPM]":"19.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"58.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"33.0","Single Cell Type RNA - Bipolar cells [nTPM]":"32.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"111.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"67.2","Single Cell Type RNA - Club cells [nTPM]":"11.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.2","Single Cell Type RNA - dendritic cells [nTPM]":"16.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"57.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"37.8","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.2","Single Cell Type RNA - Endothelial cells [nTPM]":"60.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.7","Single Cell Type RNA - Erythroid cells [nTPM]":"8.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"43.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"36.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"34.2","Single Cell Type RNA - Fibroblasts [nTPM]":"25.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.2","Single Cell Type RNA - granulocytes [nTPM]":"10.1","Single Cell Type RNA - Granulosa cells [nTPM]":"55.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.9","Single Cell Type RNA - Hepatocytes [nTPM]":"70.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.9","Single Cell Type RNA - Horizontal cells [nTPM]":"62.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"52.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.6","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"24.1","Single Cell Type RNA - Langerhans cells [nTPM]":"45.3","Single Cell Type RNA - Late spermatids [nTPM]":"5.0","Single Cell Type RNA - Leydig cells [nTPM]":"16.1","Single Cell Type RNA - Macrophages [nTPM]":"29.8","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"44.0","Single Cell Type RNA - monocytes [nTPM]":"19.0","Single Cell Type RNA - Muller glia cells [nTPM]":"56.9","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"46.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"48.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"36.6","Single Cell Type RNA - Paneth cells [nTPM]":"30.9","Single Cell Type RNA - Peritubular cells [nTPM]":"23.0","Single Cell Type RNA - Plasma cells [nTPM]":"23.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"43.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"52.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"44.0","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"36.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"36.6","Single Cell Type RNA - Spermatocytes [nTPM]":"13.1","Single Cell Type RNA - Spermatogonia [nTPM]":"20.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"24.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"57.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.4","Single Cell Type RNA - T-cells [nTPM]":"24.9","Single Cell Type RNA - Theca cells [nTPM]":"16.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.5","Single Cell Type RNA - Urothelial cells [nTPM]":"21.3"},{"Gene":"EHHADH","Gene synonym":["ECHD"],"Ensembl":"ENSG00000113790","Gene description":"Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase","Uniprot":["Q08426"],"Chromosome":"3","Position":"185190624-185281990","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Isomerase","Lyase","Multifunctional enzyme","Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"kidney":"144.3","liver":"344.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Hepatocytes":"289.0","Proximal tubular cells":"147.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"liver cancer":"42.2","renal cancer":"25.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036401","HPA042021"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036401":"AB_10670165","HPA042021":"AB_2677801"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.28e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.8","Tissue RNA - adrenal gland [nTPM]":"4.3","Tissue RNA - amygdala [nTPM]":"2.1","Tissue RNA - appendix [nTPM]":"3.0","Tissue RNA - basal ganglia [nTPM]":"2.9","Tissue RNA - bone marrow [nTPM]":"1.2","Tissue RNA - breast [nTPM]":"4.1","Tissue RNA - cerebellum [nTPM]":"3.9","Tissue RNA - cerebral cortex [nTPM]":"2.7","Tissue RNA - cervix [nTPM]":"3.5","Tissue RNA - choroid plexus [nTPM]":"9.2","Tissue RNA - colon [nTPM]":"14.2","Tissue RNA - duodenum [nTPM]":"21.5","Tissue RNA - endometrium 1 [nTPM]":"2.8","Tissue RNA - epididymis [nTPM]":"3.5","Tissue RNA - esophagus [nTPM]":"5.5","Tissue RNA - fallopian tube [nTPM]":"3.6","Tissue RNA - gallbladder [nTPM]":"4.4","Tissue RNA - heart muscle [nTPM]":"10.7","Tissue RNA - hippocampal formation [nTPM]":"2.1","Tissue RNA - hypothalamus [nTPM]":"3.1","Tissue RNA - kidney [nTPM]":"144.3","Tissue RNA - liver [nTPM]":"344.5","Tissue RNA - lung [nTPM]":"4.3","Tissue RNA - lymph node [nTPM]":"2.1","Tissue RNA - medulla oblongata [nTPM]":"3.2","Tissue RNA - midbrain [nTPM]":"4.1","Tissue RNA - ovary [nTPM]":"2.6","Tissue RNA - pancreas [nTPM]":"9.9","Tissue RNA - parathyroid gland [nTPM]":"7.8","Tissue RNA - pituitary gland [nTPM]":"1.5","Tissue RNA - placenta [nTPM]":"3.2","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"6.3","Tissue RNA - rectum [nTPM]":"10.8","Tissue RNA - retina [nTPM]":"1.6","Tissue RNA - salivary gland [nTPM]":"5.7","Tissue RNA - seminal vesicle [nTPM]":"2.2","Tissue RNA - skeletal muscle [nTPM]":"1.7","Tissue RNA - skin 1 [nTPM]":"4.5","Tissue RNA - small intestine [nTPM]":"12.9","Tissue RNA - smooth muscle [nTPM]":"3.7","Tissue RNA - spinal cord [nTPM]":"2.5","Tissue RNA - spleen [nTPM]":"3.7","Tissue RNA - stomach 1 [nTPM]":"10.4","Tissue RNA - testis [nTPM]":"2.7","Tissue RNA - thalamus [nTPM]":"3.1","Tissue RNA - thymus [nTPM]":"2.1","Tissue RNA - thyroid gland [nTPM]":"6.5","Tissue RNA - tongue [nTPM]":"5.6","Tissue RNA - tonsil [nTPM]":"2.8","Tissue RNA - urinary bladder [nTPM]":"3.6","Tissue RNA - vagina [nTPM]":"2.1","Tissue RNA - white matter [nTPM]":"2.8","Cell RNA - A-431 [nTPM]":"12.3","Cell RNA - A549 [nTPM]":"5.0","Cell RNA - AF22 [nTPM]":"1.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"7.3","Cell RNA - ASC TERT1 [nTPM]":"6.1","Cell RNA - BEWO [nTPM]":"1.5","Cell RNA - BJ [nTPM]":"5.7","Cell RNA - BJ hTERT+ [nTPM]":"1.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.1","Cell RNA - CACO-2 [nTPM]":"21.9","Cell RNA - CAPAN-2 [nTPM]":"7.5","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"22.1","Cell RNA - fHDF\/TERT166 [nTPM]":"5.7","Cell RNA - GAMG [nTPM]":"1.4","Cell RNA - HaCaT [nTPM]":"5.8","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"4.8","Cell RNA - HBF TERT88 [nTPM]":"7.6","Cell RNA - HDLM-2 [nTPM]":"16.2","Cell RNA - HEK 293 [nTPM]":"5.2","Cell RNA - HEL [nTPM]":"8.6","Cell RNA - HeLa [nTPM]":"1.3","Cell RNA - Hep G2 [nTPM]":"22.5","Cell RNA - HHSteC [nTPM]":"4.7","Cell RNA - HL-60 [nTPM]":"1.0","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"8.7","Cell RNA - hTCEpi [nTPM]":"6.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.7","Cell RNA - hTERT-HME1 [nTPM]":"3.4","Cell RNA - hTERT-RPE1 [nTPM]":"5.0","Cell RNA - HUVEC TERT2 [nTPM]":"5.5","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"5.7","Cell RNA - Karpas-707 [nTPM]":"6.1","Cell RNA - LHCN-M2 [nTPM]":"7.2","Cell RNA - MCF7 [nTPM]":"6.4","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"5.1","Cell RNA - NTERA-2 [nTPM]":"3.0","Cell RNA - OE19 [nTPM]":"4.3","Cell RNA - PC-3 [nTPM]":"6.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"9.9","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"15.4","Cell RNA - RT4 [nTPM]":"6.8","Cell RNA - SCLC-21H [nTPM]":"4.4","Cell RNA - SH-SY5Y [nTPM]":"6.4","Cell RNA - SiHa [nTPM]":"11.2","Cell RNA - SK-BR-3 [nTPM]":"6.4","Cell RNA - SK-MEL-30 [nTPM]":"10.5","Cell RNA - SuSa [nTPM]":"12.1","Cell RNA - T-47d [nTPM]":"23.7","Cell RNA - THP-1 [nTPM]":"10.1","Cell RNA - TIME [nTPM]":"2.6","Cell RNA - U-138 MG [nTPM]":"2.4","Cell RNA - U-2 OS [nTPM]":"3.6","Cell RNA - U-2197 [nTPM]":"1.9","Cell RNA - U-251 MG [nTPM]":"0.5","Cell RNA - U-266\/70 [nTPM]":"1.7","Cell RNA - U-266\/84 [nTPM]":"5.6","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"0.8","Cell RNA - U-937 [nTPM]":"3.9","Cell RNA - WM-115 [nTPM]":"4.0","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.9","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"2.4","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"1.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.2","Blood RNA - non-classical monocyte [nTPM]":"0.8","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"2.1","Brain RNA - basal ganglia [nTPM]":"2.9","Brain RNA - cerebellum [nTPM]":"3.9","Brain RNA - cerebral cortex [nTPM]":"2.7","Brain RNA - hippocampal formation [nTPM]":"2.1","Brain RNA - hypothalamus [nTPM]":"3.1","Brain RNA - medulla oblongata [nTPM]":"3.2","Brain RNA - midbrain [nTPM]":"4.1","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"2.5","Brain RNA - thalamus [nTPM]":"3.1","Brain RNA - white matter [nTPM]":"2.8","Single Cell Type RNA - Adipocytes [nTPM]":"4.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.9","Single Cell Type RNA - Astrocytes [nTPM]":"20.9","Single Cell Type RNA - B-cells [nTPM]":"4.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"3.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.9","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"2.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.1","Single Cell Type RNA - Endothelial cells [nTPM]":"3.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.7","Single Cell Type RNA - Erythroid cells [nTPM]":"9.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.9","Single Cell Type RNA - Fibroblasts [nTPM]":"1.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"6.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"289.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"10.5","Single Cell Type RNA - Langerhans cells [nTPM]":"1.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"2.7","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"9.4","Single Cell Type RNA - Muller glia cells [nTPM]":"1.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.7","Single Cell Type RNA - Paneth cells [nTPM]":"9.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"147.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.4","Single Cell Type RNA - Spermatocytes [nTPM]":"3.7","Single Cell Type RNA - Spermatogonia [nTPM]":"4.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - T-cells [nTPM]":"2.2","Single Cell Type RNA - Theca cells [nTPM]":"3.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.8","Single Cell Type RNA - Urothelial cells [nTPM]":"1.8"},{"Gene":"EI24","Gene synonym":["EPG4","PIG8","TP53I8"],"Ensembl":"ENSG00000149547","Gene description":"EI24 autophagy associated transmembrane protein","Uniprot":["O14681"],"Chromosome":"11","Position":"125569280-125584684","Protein class":["Cancer-related genes","Disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Autophagy"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"461.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"575.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"760.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047165","HPA051029"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Endoplasmic reticulum","Cytosol"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA047165":"AB_2679965","HPA051029":"AB_2681317"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.28e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Tissue RNA - adipose tissue [nTPM]":"53.4","Tissue RNA - adrenal gland [nTPM]":"32.6","Tissue RNA - amygdala [nTPM]":"61.1","Tissue RNA - appendix [nTPM]":"36.2","Tissue RNA - basal ganglia [nTPM]":"62.5","Tissue RNA - bone marrow [nTPM]":"23.2","Tissue RNA - breast [nTPM]":"72.6","Tissue RNA - cerebellum [nTPM]":"59.7","Tissue RNA - cerebral cortex [nTPM]":"72.4","Tissue RNA - cervix [nTPM]":"51.3","Tissue RNA - choroid plexus [nTPM]":"59.8","Tissue RNA - colon [nTPM]":"77.8","Tissue RNA - duodenum [nTPM]":"49.6","Tissue RNA - endometrium 1 [nTPM]":"46.2","Tissue RNA - epididymis [nTPM]":"57.4","Tissue RNA - esophagus [nTPM]":"80.8","Tissue RNA - fallopian tube [nTPM]":"50.8","Tissue RNA - gallbladder [nTPM]":"46.3","Tissue RNA - heart muscle [nTPM]":"55.7","Tissue RNA - hippocampal formation [nTPM]":"60.2","Tissue RNA - hypothalamus [nTPM]":"61.5","Tissue RNA - kidney [nTPM]":"61.0","Tissue RNA - liver [nTPM]":"248.4","Tissue RNA - lung [nTPM]":"45.0","Tissue RNA - lymph node [nTPM]":"28.4","Tissue RNA - medulla oblongata [nTPM]":"60.2","Tissue RNA - midbrain [nTPM]":"62.5","Tissue RNA - ovary [nTPM]":"42.4","Tissue RNA - pancreas [nTPM]":"101.8","Tissue RNA - parathyroid gland [nTPM]":"461.9","Tissue RNA - pituitary gland [nTPM]":"30.6","Tissue RNA - placenta [nTPM]":"48.5","Tissue RNA - pons [nTPM]":"60.2","Tissue RNA - prostate [nTPM]":"49.6","Tissue RNA - rectum [nTPM]":"80.4","Tissue RNA - retina [nTPM]":"39.4","Tissue RNA - salivary gland [nTPM]":"75.3","Tissue RNA - seminal vesicle [nTPM]":"58.0","Tissue RNA - skeletal muscle [nTPM]":"119.5","Tissue RNA - skin 1 [nTPM]":"70.2","Tissue RNA - small intestine [nTPM]":"49.3","Tissue RNA - smooth muscle [nTPM]":"62.5","Tissue RNA - spinal cord [nTPM]":"62.4","Tissue RNA - spleen [nTPM]":"30.5","Tissue RNA - stomach 1 [nTPM]":"59.7","Tissue RNA - testis [nTPM]":"33.1","Tissue RNA - thalamus [nTPM]":"64.4","Tissue RNA - thymus [nTPM]":"35.3","Tissue RNA - thyroid gland [nTPM]":"40.5","Tissue RNA - tongue [nTPM]":"104.6","Tissue RNA - tonsil [nTPM]":"42.3","Tissue RNA - urinary bladder [nTPM]":"78.9","Tissue RNA - vagina [nTPM]":"48.4","Tissue RNA - white matter [nTPM]":"61.0","Cell RNA - A-431 [nTPM]":"156.6","Cell RNA - A549 [nTPM]":"115.6","Cell RNA - AF22 [nTPM]":"129.5","Cell RNA - AN3-CA [nTPM]":"160.5","Cell RNA - ASC diff [nTPM]":"207.7","Cell RNA - ASC TERT1 [nTPM]":"155.9","Cell RNA - BEWO [nTPM]":"162.4","Cell RNA - BJ [nTPM]":"159.6","Cell RNA - BJ hTERT+ [nTPM]":"116.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"104.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"93.4","Cell RNA - CACO-2 [nTPM]":"178.9","Cell RNA - CAPAN-2 [nTPM]":"303.4","Cell RNA - Daudi [nTPM]":"158.0","Cell RNA - EFO-21 [nTPM]":"264.0","Cell RNA - fHDF\/TERT166 [nTPM]":"146.5","Cell RNA - GAMG [nTPM]":"110.8","Cell RNA - HaCaT [nTPM]":"176.1","Cell RNA - HAP1 [nTPM]":"199.0","Cell RNA - HBEC3-KT [nTPM]":"326.8","Cell RNA - HBF TERT88 [nTPM]":"135.2","Cell RNA - HDLM-2 [nTPM]":"42.0","Cell RNA - HEK 293 [nTPM]":"142.6","Cell RNA - HEL [nTPM]":"760.9","Cell RNA - HeLa [nTPM]":"77.2","Cell RNA - Hep G2 [nTPM]":"179.9","Cell RNA - HHSteC [nTPM]":"154.1","Cell RNA - HL-60 [nTPM]":"170.9","Cell RNA - HMC-1 [nTPM]":"78.4","Cell RNA - HSkMC [nTPM]":"147.5","Cell RNA - hTCEpi [nTPM]":"292.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"157.4","Cell RNA - hTERT-HME1 [nTPM]":"230.2","Cell RNA - hTERT-RPE1 [nTPM]":"102.8","Cell RNA - HUVEC TERT2 [nTPM]":"223.9","Cell RNA - JURKAT [nTPM]":"85.1","Cell RNA - K-562 [nTPM]":"351.1","Cell RNA - Karpas-707 [nTPM]":"61.1","Cell RNA - LHCN-M2 [nTPM]":"149.4","Cell RNA - MCF7 [nTPM]":"113.8","Cell RNA - MOLT-4 [nTPM]":"79.0","Cell RNA - NB-4 [nTPM]":"96.4","Cell RNA - NTERA-2 [nTPM]":"173.6","Cell RNA - OE19 [nTPM]":"398.3","Cell RNA - PC-3 [nTPM]":"139.5","Cell RNA - REH [nTPM]":"113.9","Cell RNA - RH-30 [nTPM]":"155.4","Cell RNA - RPMI-8226 [nTPM]":"132.8","Cell RNA - RPTEC TERT1 [nTPM]":"177.0","Cell RNA - RT4 [nTPM]":"272.4","Cell RNA - SCLC-21H [nTPM]":"120.1","Cell RNA - SH-SY5Y [nTPM]":"116.9","Cell RNA - SiHa [nTPM]":"187.1","Cell RNA - SK-BR-3 [nTPM]":"215.5","Cell RNA - SK-MEL-30 [nTPM]":"63.4","Cell RNA - SuSa [nTPM]":"212.3","Cell RNA - T-47d [nTPM]":"436.4","Cell RNA - THP-1 [nTPM]":"165.7","Cell RNA - TIME [nTPM]":"195.2","Cell RNA - U-138 MG [nTPM]":"133.8","Cell RNA - U-2 OS [nTPM]":"93.3","Cell RNA - U-2197 [nTPM]":"94.7","Cell RNA - U-251 MG [nTPM]":"128.7","Cell RNA - U-266\/70 [nTPM]":"39.7","Cell RNA - U-266\/84 [nTPM]":"84.8","Cell RNA - U-698 [nTPM]":"200.5","Cell RNA - U-87 MG [nTPM]":"58.5","Cell RNA - U-937 [nTPM]":"256.1","Cell RNA - WM-115 [nTPM]":"182.2","Blood RNA - basophil [nTPM]":"4.3","Blood RNA - classical monocyte [nTPM]":"7.0","Blood RNA - eosinophil [nTPM]":"5.9","Blood RNA - gdT-cell [nTPM]":"7.2","Blood RNA - intermediate monocyte [nTPM]":"6.7","Blood RNA - MAIT T-cell [nTPM]":"7.2","Blood RNA - memory B-cell [nTPM]":"8.4","Blood RNA - memory CD4 T-cell [nTPM]":"5.7","Blood RNA - memory CD8 T-cell [nTPM]":"9.0","Blood RNA - myeloid DC [nTPM]":"10.9","Blood RNA - naive B-cell [nTPM]":"6.3","Blood RNA - naive CD4 T-cell [nTPM]":"8.1","Blood RNA - naive CD8 T-cell [nTPM]":"6.7","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"6.5","Blood RNA - non-classical monocyte [nTPM]":"4.9","Blood RNA - plasmacytoid DC [nTPM]":"14.5","Blood RNA - T-reg [nTPM]":"9.1","Blood RNA - total PBMC [nTPM]":"5.3","Brain RNA - amygdala [nTPM]":"61.1","Brain RNA - basal ganglia [nTPM]":"62.5","Brain RNA - cerebellum [nTPM]":"59.7","Brain RNA - cerebral cortex [nTPM]":"72.4","Brain RNA - hippocampal formation [nTPM]":"60.2","Brain RNA - hypothalamus [nTPM]":"61.5","Brain RNA - medulla oblongata [nTPM]":"60.2","Brain RNA - midbrain [nTPM]":"62.5","Brain RNA - pons [nTPM]":"60.2","Brain RNA - spinal cord [nTPM]":"62.4","Brain RNA - thalamus [nTPM]":"64.4","Brain RNA - white matter [nTPM]":"61.0","Single Cell Type RNA - Adipocytes [nTPM]":"73.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"38.3","Single Cell Type RNA - Astrocytes [nTPM]":"13.4","Single Cell Type RNA - B-cells [nTPM]":"34.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"120.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"130.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"132.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"120.1","Single Cell Type RNA - Bipolar cells [nTPM]":"58.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"148.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"100.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"61.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"124.4","Single Cell Type RNA - Club cells [nTPM]":"69.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"110.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"166.9","Single Cell Type RNA - dendritic cells [nTPM]":"32.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"66.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"144.8","Single Cell Type RNA - Ductal cells [nTPM]":"178.6","Single Cell Type RNA - Early spermatids [nTPM]":"31.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"34.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"59.3","Single Cell Type RNA - Endothelial cells [nTPM]":"87.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"98.4","Single Cell Type RNA - Erythroid cells [nTPM]":"102.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"181.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"201.2","Single Cell Type RNA - Fibroblasts [nTPM]":"80.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"87.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"46.5","Single Cell Type RNA - granulocytes [nTPM]":"27.3","Single Cell Type RNA - Granulosa cells [nTPM]":"76.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"74.6","Single Cell Type RNA - Hepatocytes [nTPM]":"575.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"110.5","Single Cell Type RNA - Horizontal cells [nTPM]":"82.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"115.3","Single Cell Type RNA - Ionocytes [nTPM]":"105.8","Single Cell Type RNA - Kupffer cells [nTPM]":"49.8","Single Cell Type RNA - Langerhans cells [nTPM]":"96.1","Single Cell Type RNA - Late spermatids [nTPM]":"49.7","Single Cell Type RNA - Leydig cells [nTPM]":"71.4","Single Cell Type RNA - Macrophages [nTPM]":"40.9","Single Cell Type RNA - Melanocytes [nTPM]":"90.7","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"40.9","Single Cell Type RNA - Muller glia cells [nTPM]":"107.1","Single Cell Type RNA - NK-cells [nTPM]":"50.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"23.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"182.1","Single Cell Type RNA - Paneth cells [nTPM]":"67.6","Single Cell Type RNA - Peritubular cells [nTPM]":"72.2","Single Cell Type RNA - Plasma cells [nTPM]":"79.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"270.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"68.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"122.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"43.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"36.9","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"60.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"80.1","Single Cell Type RNA - Spermatocytes [nTPM]":"95.9","Single Cell Type RNA - Spermatogonia [nTPM]":"112.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"176.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"181.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"140.1","Single Cell Type RNA - T-cells [nTPM]":"31.0","Single Cell Type RNA - Theca cells [nTPM]":"71.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"135.7","Single Cell Type RNA - Urothelial cells [nTPM]":"189.4"},{"Gene":"EIF2AK1","Gene synonym":["HRI","KIAA1369"],"Ensembl":"ENSG00000086232","Gene description":"Eukaryotic translation initiation factor 2 alpha kinase 1","Uniprot":["Q9BQI3"],"Chromosome":"7","Position":"6022247-6059175","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Protein synthesis inhibitor","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cytotrophoblasts":"219.1","Erythroid cells":"422.0","Syncytiotrophoblasts":"371.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016496","CAB022082","HPA061675"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB022082":null,"HPA016496":"AB_1848057","HPA061675":"AB_2684583"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.69e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.99e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Tissue RNA - adipose tissue [nTPM]":"27.2","Tissue RNA - adrenal gland [nTPM]":"39.4","Tissue RNA - amygdala [nTPM]":"28.1","Tissue RNA - appendix [nTPM]":"27.7","Tissue RNA - basal ganglia [nTPM]":"28.9","Tissue RNA - bone marrow [nTPM]":"105.9","Tissue RNA - breast [nTPM]":"35.9","Tissue RNA - cerebellum [nTPM]":"30.6","Tissue RNA - cerebral cortex [nTPM]":"36.1","Tissue RNA - cervix [nTPM]":"29.0","Tissue RNA - choroid plexus [nTPM]":"34.9","Tissue RNA - colon [nTPM]":"48.8","Tissue RNA - duodenum [nTPM]":"37.1","Tissue RNA - endometrium 1 [nTPM]":"25.0","Tissue RNA - epididymis [nTPM]":"37.4","Tissue RNA - esophagus [nTPM]":"30.4","Tissue RNA - fallopian tube [nTPM]":"31.0","Tissue RNA - gallbladder [nTPM]":"23.8","Tissue RNA - heart muscle [nTPM]":"33.8","Tissue RNA - hippocampal formation [nTPM]":"28.1","Tissue RNA - hypothalamus [nTPM]":"30.6","Tissue RNA - kidney [nTPM]":"43.8","Tissue RNA - liver [nTPM]":"65.1","Tissue RNA - lung [nTPM]":"30.3","Tissue RNA - lymph node [nTPM]":"35.2","Tissue RNA - medulla oblongata [nTPM]":"30.5","Tissue RNA - midbrain [nTPM]":"28.9","Tissue RNA - ovary [nTPM]":"29.3","Tissue RNA - pancreas [nTPM]":"44.3","Tissue RNA - parathyroid gland [nTPM]":"78.0","Tissue RNA - pituitary gland [nTPM]":"25.9","Tissue RNA - placenta [nTPM]":"52.3","Tissue RNA - pons [nTPM]":"31.6","Tissue RNA - prostate [nTPM]":"35.0","Tissue RNA - rectum [nTPM]":"47.3","Tissue RNA - retina [nTPM]":"29.0","Tissue RNA - salivary gland [nTPM]":"46.8","Tissue RNA - seminal vesicle [nTPM]":"24.2","Tissue RNA - skeletal muscle [nTPM]":"38.3","Tissue RNA - skin 1 [nTPM]":"33.3","Tissue RNA - small intestine [nTPM]":"37.2","Tissue RNA - smooth muscle [nTPM]":"23.8","Tissue RNA - spinal cord [nTPM]":"29.1","Tissue RNA - spleen [nTPM]":"26.6","Tissue RNA - stomach 1 [nTPM]":"49.1","Tissue RNA - testis [nTPM]":"19.5","Tissue RNA - thalamus [nTPM]":"29.8","Tissue RNA - thymus [nTPM]":"43.6","Tissue RNA - thyroid gland [nTPM]":"39.3","Tissue RNA - tongue [nTPM]":"34.4","Tissue RNA - tonsil [nTPM]":"40.4","Tissue RNA - urinary bladder [nTPM]":"27.2","Tissue RNA - vagina [nTPM]":"22.4","Tissue RNA - white matter [nTPM]":"33.7","Cell RNA - A-431 [nTPM]":"144.5","Cell RNA - A549 [nTPM]":"90.5","Cell RNA - AF22 [nTPM]":"71.2","Cell RNA - AN3-CA [nTPM]":"108.8","Cell RNA - ASC diff [nTPM]":"66.4","Cell RNA - ASC TERT1 [nTPM]":"59.6","Cell RNA - BEWO [nTPM]":"92.4","Cell RNA - BJ [nTPM]":"73.0","Cell RNA - BJ hTERT+ [nTPM]":"66.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"64.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"80.8","Cell RNA - CACO-2 [nTPM]":"83.7","Cell RNA - CAPAN-2 [nTPM]":"96.2","Cell RNA - Daudi [nTPM]":"112.5","Cell RNA - EFO-21 [nTPM]":"77.4","Cell RNA - fHDF\/TERT166 [nTPM]":"81.3","Cell RNA - GAMG [nTPM]":"115.5","Cell RNA - HaCaT [nTPM]":"100.4","Cell RNA - HAP1 [nTPM]":"93.1","Cell RNA - HBEC3-KT [nTPM]":"67.1","Cell RNA - HBF TERT88 [nTPM]":"82.2","Cell RNA - HDLM-2 [nTPM]":"69.8","Cell RNA - HEK 293 [nTPM]":"140.3","Cell RNA - HEL [nTPM]":"115.9","Cell RNA - HeLa [nTPM]":"91.6","Cell RNA - Hep G2 [nTPM]":"127.3","Cell RNA - HHSteC [nTPM]":"54.3","Cell RNA - HL-60 [nTPM]":"100.8","Cell RNA - HMC-1 [nTPM]":"102.0","Cell RNA - HSkMC [nTPM]":"48.1","Cell RNA - hTCEpi [nTPM]":"82.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"60.7","Cell RNA - hTERT-HME1 [nTPM]":"64.9","Cell RNA - hTERT-RPE1 [nTPM]":"67.7","Cell RNA - HUVEC TERT2 [nTPM]":"69.4","Cell RNA - JURKAT [nTPM]":"88.1","Cell RNA - K-562 [nTPM]":"189.0","Cell RNA - Karpas-707 [nTPM]":"106.8","Cell RNA - LHCN-M2 [nTPM]":"61.4","Cell RNA - MCF7 [nTPM]":"146.5","Cell RNA - MOLT-4 [nTPM]":"55.6","Cell RNA - NB-4 [nTPM]":"128.6","Cell RNA - NTERA-2 [nTPM]":"88.5","Cell RNA - OE19 [nTPM]":"84.6","Cell RNA - PC-3 [nTPM]":"99.7","Cell RNA - REH [nTPM]":"120.0","Cell RNA - RH-30 [nTPM]":"74.6","Cell RNA - RPMI-8226 [nTPM]":"134.0","Cell RNA - RPTEC TERT1 [nTPM]":"82.3","Cell RNA - RT4 [nTPM]":"70.3","Cell RNA - SCLC-21H [nTPM]":"87.3","Cell RNA - SH-SY5Y [nTPM]":"156.5","Cell RNA - SiHa [nTPM]":"139.3","Cell RNA - SK-BR-3 [nTPM]":"186.6","Cell RNA - SK-MEL-30 [nTPM]":"63.8","Cell RNA - SuSa [nTPM]":"98.6","Cell RNA - T-47d [nTPM]":"141.0","Cell RNA - THP-1 [nTPM]":"122.4","Cell RNA - TIME [nTPM]":"65.9","Cell RNA - U-138 MG [nTPM]":"37.0","Cell RNA - U-2 OS [nTPM]":"134.2","Cell RNA - U-2197 [nTPM]":"65.3","Cell RNA - U-251 MG [nTPM]":"78.2","Cell RNA - U-266\/70 [nTPM]":"106.5","Cell RNA - U-266\/84 [nTPM]":"114.8","Cell RNA - U-698 [nTPM]":"115.6","Cell RNA - U-87 MG [nTPM]":"73.9","Cell RNA - U-937 [nTPM]":"129.8","Cell RNA - WM-115 [nTPM]":"108.7","Blood RNA - basophil [nTPM]":"11.1","Blood RNA - classical monocyte [nTPM]":"6.9","Blood RNA - eosinophil [nTPM]":"17.3","Blood RNA - gdT-cell [nTPM]":"8.2","Blood RNA - intermediate monocyte [nTPM]":"5.5","Blood RNA - MAIT T-cell [nTPM]":"5.6","Blood RNA - memory B-cell [nTPM]":"12.3","Blood RNA - memory CD4 T-cell [nTPM]":"6.5","Blood RNA - memory CD8 T-cell [nTPM]":"9.3","Blood RNA - myeloid DC [nTPM]":"6.9","Blood RNA - naive B-cell [nTPM]":"9.5","Blood RNA - naive CD4 T-cell [nTPM]":"7.5","Blood RNA - naive CD8 T-cell [nTPM]":"6.6","Blood RNA - neutrophil [nTPM]":"3.7","Blood RNA - NK-cell [nTPM]":"10.2","Blood RNA - non-classical monocyte [nTPM]":"6.2","Blood RNA - plasmacytoid DC [nTPM]":"6.0","Blood RNA - T-reg [nTPM]":"8.9","Blood RNA - total PBMC [nTPM]":"4.8","Brain RNA - amygdala [nTPM]":"28.1","Brain RNA - basal ganglia [nTPM]":"28.9","Brain RNA - cerebellum [nTPM]":"30.6","Brain RNA - cerebral cortex [nTPM]":"36.1","Brain RNA - hippocampal formation [nTPM]":"28.1","Brain RNA - hypothalamus [nTPM]":"30.6","Brain RNA - medulla oblongata [nTPM]":"30.5","Brain RNA - midbrain [nTPM]":"28.9","Brain RNA - pons [nTPM]":"31.6","Brain RNA - spinal cord [nTPM]":"29.1","Brain RNA - thalamus [nTPM]":"29.8","Brain RNA - white matter [nTPM]":"33.7","Single Cell Type RNA - Adipocytes [nTPM]":"23.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"43.7","Single Cell Type RNA - Astrocytes [nTPM]":"14.4","Single Cell Type RNA - B-cells [nTPM]":"42.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"23.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"34.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"34.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"41.5","Single Cell Type RNA - Bipolar cells [nTPM]":"29.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"52.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"34.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"49.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"45.8","Single Cell Type RNA - Club cells [nTPM]":"37.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"219.1","Single Cell Type RNA - dendritic cells [nTPM]":"52.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"57.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"66.5","Single Cell Type RNA - Ductal cells [nTPM]":"55.0","Single Cell Type RNA - Early spermatids [nTPM]":"8.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"59.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"42.3","Single Cell Type RNA - Endothelial cells [nTPM]":"27.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"38.5","Single Cell Type RNA - Erythroid cells [nTPM]":"422.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"21.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"44.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"82.1","Single Cell Type RNA - Fibroblasts [nTPM]":"29.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"64.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"48.1","Single Cell Type RNA - granulocytes [nTPM]":"20.8","Single Cell Type RNA - Granulosa cells [nTPM]":"44.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.0","Single Cell Type RNA - Hepatocytes [nTPM]":"63.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"53.8","Single Cell Type RNA - Horizontal cells [nTPM]":"32.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"68.7","Single Cell Type RNA - Ionocytes [nTPM]":"54.9","Single Cell Type RNA - Kupffer cells [nTPM]":"39.0","Single Cell Type RNA - Langerhans cells [nTPM]":"29.9","Single Cell Type RNA - Late spermatids [nTPM]":"16.1","Single Cell Type RNA - Leydig cells [nTPM]":"34.5","Single Cell Type RNA - Macrophages [nTPM]":"65.2","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"62.8","Single Cell Type RNA - Muller glia cells [nTPM]":"46.4","Single Cell Type RNA - NK-cells [nTPM]":"70.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"26.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"53.0","Single Cell Type RNA - Paneth cells [nTPM]":"47.0","Single Cell Type RNA - Peritubular cells [nTPM]":"37.6","Single Cell Type RNA - Plasma cells [nTPM]":"60.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"43.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"47.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"66.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"48.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"26.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"32.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.0","Single Cell Type RNA - Spermatocytes [nTPM]":"33.7","Single Cell Type RNA - Spermatogonia [nTPM]":"34.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"45.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"371.0","Single Cell Type RNA - T-cells [nTPM]":"38.0","Single Cell Type RNA - Theca cells [nTPM]":"57.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"52.7","Single Cell Type RNA - Urothelial cells [nTPM]":"32.3"},{"Gene":"EIF2AK2","Gene synonym":["EIF2AK1","PKR","PPP1R83","PRKR"],"Ensembl":"ENSG00000055332","Gene description":"Eukaryotic translation initiation factor 2 alpha kinase 2","Uniprot":["P19525"],"Chromosome":"2","Position":"37099210-37157522","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Antiviral defense","Host-virus interaction","Immunity","Innate immunity","Transcription","Transcription regulation"],"Molecular function":["Kinase","RNA-binding","Serine\/threonine-protein kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003845","HPA019795","HPA063893"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"44000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB003845":"AB_562332","HPA019795":"AB_1848060","HPA063893":"AB_2685144"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.77e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.08e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.1","Tissue RNA - adrenal gland [nTPM]":"9.0","Tissue RNA - amygdala [nTPM]":"7.2","Tissue RNA - appendix [nTPM]":"10.5","Tissue RNA - basal ganglia [nTPM]":"8.1","Tissue RNA - bone marrow [nTPM]":"30.1","Tissue RNA - breast [nTPM]":"8.6","Tissue RNA - cerebellum [nTPM]":"7.4","Tissue RNA - cerebral cortex [nTPM]":"9.5","Tissue RNA - cervix [nTPM]":"9.8","Tissue RNA - choroid plexus [nTPM]":"8.6","Tissue RNA - colon [nTPM]":"8.8","Tissue RNA - duodenum [nTPM]":"7.6","Tissue RNA - endometrium 1 [nTPM]":"10.5","Tissue RNA - epididymis [nTPM]":"8.0","Tissue RNA - esophagus [nTPM]":"6.3","Tissue RNA - fallopian tube [nTPM]":"8.3","Tissue RNA - gallbladder [nTPM]":"9.5","Tissue RNA - heart muscle [nTPM]":"6.3","Tissue RNA - hippocampal formation [nTPM]":"7.8","Tissue RNA - hypothalamus [nTPM]":"11.1","Tissue RNA - kidney [nTPM]":"8.5","Tissue RNA - liver [nTPM]":"7.7","Tissue RNA - lung [nTPM]":"8.9","Tissue RNA - lymph node [nTPM]":"8.0","Tissue RNA - medulla oblongata [nTPM]":"10.9","Tissue RNA - midbrain [nTPM]":"8.1","Tissue RNA - ovary [nTPM]":"10.8","Tissue RNA - pancreas [nTPM]":"7.4","Tissue RNA - parathyroid gland [nTPM]":"11.1","Tissue RNA - pituitary gland [nTPM]":"6.6","Tissue RNA - placenta [nTPM]":"11.2","Tissue RNA - pons [nTPM]":"10.9","Tissue RNA - prostate [nTPM]":"10.1","Tissue RNA - rectum [nTPM]":"8.6","Tissue RNA - retina [nTPM]":"6.6","Tissue RNA - salivary gland [nTPM]":"17.7","Tissue RNA - seminal vesicle [nTPM]":"8.4","Tissue RNA - skeletal muscle [nTPM]":"4.5","Tissue RNA - skin 1 [nTPM]":"4.6","Tissue RNA - small intestine [nTPM]":"9.9","Tissue RNA - smooth muscle [nTPM]":"11.1","Tissue RNA - spinal cord [nTPM]":"15.6","Tissue RNA - spleen [nTPM]":"11.9","Tissue RNA - stomach 1 [nTPM]":"9.5","Tissue RNA - testis [nTPM]":"3.3","Tissue RNA - thalamus [nTPM]":"13.0","Tissue RNA - thymus [nTPM]":"11.7","Tissue RNA - thyroid gland [nTPM]":"10.0","Tissue RNA - tongue [nTPM]":"5.8","Tissue RNA - tonsil [nTPM]":"7.1","Tissue RNA - urinary bladder [nTPM]":"8.0","Tissue RNA - vagina [nTPM]":"5.9","Tissue RNA - white matter [nTPM]":"8.7","Cell RNA - A-431 [nTPM]":"38.4","Cell RNA - A549 [nTPM]":"22.1","Cell RNA - AF22 [nTPM]":"16.7","Cell RNA - AN3-CA [nTPM]":"17.4","Cell RNA - ASC diff [nTPM]":"21.5","Cell RNA - ASC TERT1 [nTPM]":"28.3","Cell RNA - BEWO [nTPM]":"20.1","Cell RNA - BJ [nTPM]":"21.2","Cell RNA - BJ hTERT+ [nTPM]":"29.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"56.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"41.1","Cell RNA - CACO-2 [nTPM]":"23.0","Cell RNA - CAPAN-2 [nTPM]":"23.2","Cell RNA - Daudi [nTPM]":"27.4","Cell RNA - EFO-21 [nTPM]":"27.0","Cell RNA - fHDF\/TERT166 [nTPM]":"29.8","Cell RNA - GAMG [nTPM]":"66.2","Cell RNA - HaCaT [nTPM]":"27.4","Cell RNA - HAP1 [nTPM]":"24.2","Cell RNA - HBEC3-KT [nTPM]":"27.1","Cell RNA - HBF TERT88 [nTPM]":"29.5","Cell RNA - HDLM-2 [nTPM]":"45.7","Cell RNA - HEK 293 [nTPM]":"12.0","Cell RNA - HEL [nTPM]":"33.8","Cell RNA - HeLa [nTPM]":"19.2","Cell RNA - Hep G2 [nTPM]":"18.7","Cell RNA - HHSteC [nTPM]":"17.9","Cell RNA - HL-60 [nTPM]":"32.2","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"22.5","Cell RNA - hTCEpi [nTPM]":"13.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"23.7","Cell RNA - hTERT-HME1 [nTPM]":"19.3","Cell RNA - hTERT-RPE1 [nTPM]":"17.7","Cell RNA - HUVEC TERT2 [nTPM]":"18.0","Cell RNA - JURKAT [nTPM]":"10.7","Cell RNA - K-562 [nTPM]":"19.1","Cell RNA - Karpas-707 [nTPM]":"23.6","Cell RNA - LHCN-M2 [nTPM]":"20.3","Cell RNA - MCF7 [nTPM]":"13.4","Cell RNA - MOLT-4 [nTPM]":"35.5","Cell RNA - NB-4 [nTPM]":"17.0","Cell RNA - NTERA-2 [nTPM]":"15.8","Cell RNA - OE19 [nTPM]":"8.4","Cell RNA - PC-3 [nTPM]":"10.8","Cell RNA - REH [nTPM]":"27.6","Cell RNA - RH-30 [nTPM]":"40.9","Cell RNA - RPMI-8226 [nTPM]":"12.1","Cell RNA - RPTEC TERT1 [nTPM]":"15.3","Cell RNA - RT4 [nTPM]":"18.7","Cell RNA - SCLC-21H [nTPM]":"14.1","Cell RNA - SH-SY5Y [nTPM]":"20.4","Cell RNA - SiHa [nTPM]":"32.0","Cell RNA - SK-BR-3 [nTPM]":"24.0","Cell RNA - SK-MEL-30 [nTPM]":"50.7","Cell RNA - SuSa [nTPM]":"12.7","Cell RNA - T-47d [nTPM]":"9.2","Cell RNA - THP-1 [nTPM]":"9.0","Cell RNA - TIME [nTPM]":"31.4","Cell RNA - U-138 MG [nTPM]":"25.7","Cell RNA - U-2 OS [nTPM]":"24.9","Cell RNA - U-2197 [nTPM]":"15.1","Cell RNA - U-251 MG [nTPM]":"36.2","Cell RNA - U-266\/70 [nTPM]":"19.0","Cell RNA - U-266\/84 [nTPM]":"30.8","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"15.9","Cell RNA - U-937 [nTPM]":"20.0","Cell RNA - WM-115 [nTPM]":"23.1","Blood RNA - basophil [nTPM]":"10.7","Blood RNA - classical monocyte [nTPM]":"5.3","Blood RNA - eosinophil [nTPM]":"6.3","Blood RNA - gdT-cell [nTPM]":"5.4","Blood RNA - intermediate monocyte [nTPM]":"7.9","Blood RNA - MAIT T-cell [nTPM]":"5.2","Blood RNA - memory B-cell [nTPM]":"5.3","Blood RNA - memory CD4 T-cell [nTPM]":"4.5","Blood RNA - memory CD8 T-cell [nTPM]":"5.2","Blood RNA - myeloid DC [nTPM]":"4.8","Blood RNA - naive B-cell [nTPM]":"4.2","Blood RNA - naive CD4 T-cell [nTPM]":"3.0","Blood RNA - naive CD8 T-cell [nTPM]":"4.3","Blood RNA - neutrophil [nTPM]":"15.7","Blood RNA - NK-cell [nTPM]":"6.5","Blood RNA - non-classical monocyte [nTPM]":"8.0","Blood RNA - plasmacytoid DC [nTPM]":"3.1","Blood RNA - T-reg [nTPM]":"6.5","Blood RNA - total PBMC [nTPM]":"2.1","Brain RNA - amygdala [nTPM]":"7.2","Brain RNA - basal ganglia [nTPM]":"8.1","Brain RNA - cerebellum [nTPM]":"7.4","Brain RNA - cerebral cortex [nTPM]":"9.5","Brain RNA - hippocampal formation [nTPM]":"7.8","Brain RNA - hypothalamus [nTPM]":"11.1","Brain RNA - medulla oblongata [nTPM]":"10.9","Brain RNA - midbrain [nTPM]":"8.1","Brain RNA - pons [nTPM]":"10.9","Brain RNA - spinal cord [nTPM]":"15.6","Brain RNA - thalamus [nTPM]":"13.0","Brain RNA - white matter [nTPM]":"8.7","Single Cell Type RNA - Adipocytes [nTPM]":"94.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"67.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"34.0","Single Cell Type RNA - Astrocytes [nTPM]":"25.1","Single Cell Type RNA - B-cells [nTPM]":"35.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"19.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"42.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"33.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.3","Single Cell Type RNA - Bipolar cells [nTPM]":"38.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"26.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"29.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"46.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"47.8","Single Cell Type RNA - dendritic cells [nTPM]":"44.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"32.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"40.2","Single Cell Type RNA - Early spermatids [nTPM]":"2.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"55.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"68.7","Single Cell Type RNA - Endothelial cells [nTPM]":"76.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.0","Single Cell Type RNA - Erythroid cells [nTPM]":"36.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"39.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"48.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"89.2","Single Cell Type RNA - Fibroblasts [nTPM]":"52.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"22.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"41.7","Single Cell Type RNA - granulocytes [nTPM]":"41.1","Single Cell Type RNA - Granulosa cells [nTPM]":"93.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"33.5","Single Cell Type RNA - Hepatocytes [nTPM]":"21.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"38.2","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"42.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.0","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"29.9","Single Cell Type RNA - Langerhans cells [nTPM]":"20.8","Single Cell Type RNA - Late spermatids [nTPM]":"4.2","Single Cell Type RNA - Leydig cells [nTPM]":"57.2","Single Cell Type RNA - Macrophages [nTPM]":"50.7","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"48.7","Single Cell Type RNA - monocytes [nTPM]":"47.1","Single Cell Type RNA - Muller glia cells [nTPM]":"50.9","Single Cell Type RNA - NK-cells [nTPM]":"45.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"51.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"54.7","Single Cell Type RNA - Paneth cells [nTPM]":"21.8","Single Cell Type RNA - Peritubular cells [nTPM]":"84.2","Single Cell Type RNA - Plasma cells [nTPM]":"46.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"39.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"33.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"33.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"48.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.8","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"60.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"45.9","Single Cell Type RNA - Spermatocytes [nTPM]":"2.4","Single Cell Type RNA - Spermatogonia [nTPM]":"5.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"40.8","Single Cell Type RNA - T-cells [nTPM]":"40.0","Single Cell Type RNA - Theca cells [nTPM]":"61.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"28.6","Single Cell Type RNA - Urothelial cells [nTPM]":"40.5"},{"Gene":"EIF2AK3","Gene synonym":["PEK","PERK"],"Ensembl":"ENSG00000172071","Gene description":"Eukaryotic translation initiation factor 2 alpha kinase 3","Uniprot":["Q9NZJ5"],"Chromosome":"2","Position":"88556741-88627464","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Stress response","Translation regulation","Unfolded protein response"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"19.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"121.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"1.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"46.8","U-266\/70":"44.0","U-698":"31.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009204","HPA015737"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009204":"AB_2230863","HPA015737":"AB_1848062"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-3"},"Tissue RNA - adipose tissue [nTPM]":"3.3","Tissue RNA - adrenal gland [nTPM]":"3.1","Tissue RNA - amygdala [nTPM]":"0.8","Tissue RNA - appendix [nTPM]":"4.0","Tissue RNA - basal ganglia [nTPM]":"1.1","Tissue RNA - bone marrow [nTPM]":"2.6","Tissue RNA - breast [nTPM]":"1.6","Tissue RNA - cerebellum [nTPM]":"1.6","Tissue RNA - cerebral cortex [nTPM]":"1.4","Tissue RNA - cervix [nTPM]":"2.3","Tissue RNA - choroid plexus [nTPM]":"1.6","Tissue RNA - colon [nTPM]":"4.7","Tissue RNA - duodenum [nTPM]":"6.2","Tissue RNA - endometrium 1 [nTPM]":"1.9","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"1.6","Tissue RNA - fallopian tube [nTPM]":"1.3","Tissue RNA - gallbladder [nTPM]":"1.4","Tissue RNA - heart muscle [nTPM]":"1.5","Tissue RNA - hippocampal formation [nTPM]":"0.8","Tissue RNA - hypothalamus [nTPM]":"1.5","Tissue RNA - kidney [nTPM]":"2.0","Tissue RNA - liver [nTPM]":"1.9","Tissue RNA - lung [nTPM]":"1.8","Tissue RNA - lymph node [nTPM]":"3.2","Tissue RNA - medulla oblongata [nTPM]":"1.0","Tissue RNA - midbrain [nTPM]":"1.2","Tissue RNA - ovary [nTPM]":"1.9","Tissue RNA - pancreas [nTPM]":"19.6","Tissue RNA - parathyroid gland [nTPM]":"3.4","Tissue RNA - pituitary gland [nTPM]":"1.1","Tissue RNA - placenta [nTPM]":"3.2","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"4.0","Tissue RNA - rectum [nTPM]":"1.8","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"9.7","Tissue RNA - seminal vesicle [nTPM]":"1.2","Tissue RNA - skeletal muscle [nTPM]":"2.0","Tissue RNA - skin 1 [nTPM]":"1.4","Tissue RNA - small intestine [nTPM]":"5.0","Tissue RNA - smooth muscle [nTPM]":"0.9","Tissue RNA - spinal cord [nTPM]":"1.5","Tissue RNA - spleen [nTPM]":"3.1","Tissue RNA - stomach 1 [nTPM]":"12.3","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"1.3","Tissue RNA - thyroid gland [nTPM]":"3.5","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"2.3","Tissue RNA - urinary bladder [nTPM]":"1.9","Tissue RNA - vagina [nTPM]":"1.8","Tissue RNA - white matter [nTPM]":"2.1","Cell RNA - A-431 [nTPM]":"8.7","Cell RNA - A549 [nTPM]":"3.3","Cell RNA - AF22 [nTPM]":"1.2","Cell RNA - AN3-CA [nTPM]":"4.3","Cell RNA - ASC diff [nTPM]":"2.8","Cell RNA - ASC TERT1 [nTPM]":"2.0","Cell RNA - BEWO [nTPM]":"15.9","Cell RNA - BJ [nTPM]":"12.4","Cell RNA - BJ hTERT+ [nTPM]":"1.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.1","Cell RNA - CACO-2 [nTPM]":"3.5","Cell RNA - CAPAN-2 [nTPM]":"2.9","Cell RNA - Daudi [nTPM]":"46.8","Cell RNA - EFO-21 [nTPM]":"8.0","Cell RNA - fHDF\/TERT166 [nTPM]":"1.3","Cell RNA - GAMG [nTPM]":"3.1","Cell RNA - HaCaT [nTPM]":"7.2","Cell RNA - HAP1 [nTPM]":"1.6","Cell RNA - HBEC3-KT [nTPM]":"1.3","Cell RNA - HBF TERT88 [nTPM]":"1.1","Cell RNA - HDLM-2 [nTPM]":"25.3","Cell RNA - HEK 293 [nTPM]":"7.1","Cell RNA - HEL [nTPM]":"4.6","Cell RNA - HeLa [nTPM]":"1.7","Cell RNA - Hep G2 [nTPM]":"2.0","Cell RNA - HHSteC [nTPM]":"1.1","Cell RNA - HL-60 [nTPM]":"3.9","Cell RNA - HMC-1 [nTPM]":"12.3","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"1.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.7","Cell RNA - hTERT-HME1 [nTPM]":"2.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.8","Cell RNA - HUVEC TERT2 [nTPM]":"1.4","Cell RNA - JURKAT [nTPM]":"4.9","Cell RNA - K-562 [nTPM]":"3.0","Cell RNA - Karpas-707 [nTPM]":"8.7","Cell RNA - LHCN-M2 [nTPM]":"0.6","Cell RNA - MCF7 [nTPM]":"4.4","Cell RNA - MOLT-4 [nTPM]":"5.5","Cell RNA - NB-4 [nTPM]":"2.2","Cell RNA - NTERA-2 [nTPM]":"6.2","Cell RNA - OE19 [nTPM]":"2.7","Cell RNA - PC-3 [nTPM]":"7.2","Cell RNA - REH [nTPM]":"25.1","Cell RNA - RH-30 [nTPM]":"7.0","Cell RNA - RPMI-8226 [nTPM]":"8.2","Cell RNA - RPTEC TERT1 [nTPM]":"1.3","Cell RNA - RT4 [nTPM]":"5.0","Cell RNA - SCLC-21H [nTPM]":"5.6","Cell RNA - SH-SY5Y [nTPM]":"9.9","Cell RNA - SiHa [nTPM]":"6.3","Cell RNA - SK-BR-3 [nTPM]":"6.5","Cell RNA - SK-MEL-30 [nTPM]":"8.2","Cell RNA - SuSa [nTPM]":"1.7","Cell RNA - T-47d [nTPM]":"2.2","Cell RNA - THP-1 [nTPM]":"4.4","Cell RNA - TIME [nTPM]":"3.9","Cell RNA - U-138 MG [nTPM]":"2.5","Cell RNA - U-2 OS [nTPM]":"5.5","Cell RNA - U-2197 [nTPM]":"10.8","Cell RNA - U-251 MG [nTPM]":"7.1","Cell RNA - U-266\/70 [nTPM]":"44.0","Cell RNA - U-266\/84 [nTPM]":"24.4","Cell RNA - U-698 [nTPM]":"31.0","Cell RNA - U-87 MG [nTPM]":"4.6","Cell RNA - U-937 [nTPM]":"4.2","Cell RNA - WM-115 [nTPM]":"6.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"1.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"1.9","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.8","Brain RNA - basal ganglia [nTPM]":"1.1","Brain RNA - cerebellum [nTPM]":"1.6","Brain RNA - cerebral cortex [nTPM]":"1.4","Brain RNA - hippocampal formation [nTPM]":"0.8","Brain RNA - hypothalamus [nTPM]":"1.5","Brain RNA - medulla oblongata [nTPM]":"1.0","Brain RNA - midbrain [nTPM]":"1.2","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"1.5","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"2.1","Single Cell Type RNA - Adipocytes [nTPM]":"9.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.5","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"43.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.7","Single Cell Type RNA - Bipolar cells [nTPM]":"8.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"7.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.1","Single Cell Type RNA - dendritic cells [nTPM]":"13.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.3","Single Cell Type RNA - Endothelial cells [nTPM]":"7.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.7","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"31.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.9","Single Cell Type RNA - Fibroblasts [nTPM]":"15.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"40.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"39.2","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"4.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.9","Single Cell Type RNA - Hepatocytes [nTPM]":"11.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.6","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"39.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"30.1","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.1","Single Cell Type RNA - Langerhans cells [nTPM]":"41.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"7.5","Single Cell Type RNA - Macrophages [nTPM]":"27.7","Single Cell Type RNA - Melanocytes [nTPM]":"32.0","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"3.9","Single Cell Type RNA - Muller glia cells [nTPM]":"3.0","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"26.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.0","Single Cell Type RNA - Paneth cells [nTPM]":"7.7","Single Cell Type RNA - Peritubular cells [nTPM]":"5.7","Single Cell Type RNA - Plasma cells [nTPM]":"121.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.4","Single Cell Type RNA - Spermatocytes [nTPM]":"3.1","Single Cell Type RNA - Spermatogonia [nTPM]":"3.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.7","Single Cell Type RNA - T-cells [nTPM]":"12.8","Single Cell Type RNA - Theca cells [nTPM]":"3.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.8","Single Cell Type RNA - Urothelial cells [nTPM]":"16.6"},{"Gene":"EIF2AK4","Gene synonym":["GCN2","KIAA1338"],"Ensembl":"ENSG00000128829","Gene description":"Eukaryotic translation initiation factor 2 alpha kinase 4","Uniprot":["Q9P2K8"],"Chromosome":"15","Position":"39934115-40035591","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Activation of host autophagy by virus","Adaptive immunity","Antiviral defense","Cell cycle","Growth arrest","Host-virus interaction","Immunity","Neurogenesis","Stress response","Translation regulation"],"Molecular function":["Activator","Kinase","RNA-binding","Serine\/threonine-protein kinase","Transferase","tRNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"66.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011811"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 65: Plasmacytoid DCs - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA011811":"AB_2668543"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-3"},"Tissue RNA - adipose tissue [nTPM]":"20.1","Tissue RNA - adrenal gland [nTPM]":"14.6","Tissue RNA - amygdala [nTPM]":"21.5","Tissue RNA - appendix [nTPM]":"12.2","Tissue RNA - basal ganglia [nTPM]":"22.4","Tissue RNA - bone marrow [nTPM]":"18.7","Tissue RNA - breast [nTPM]":"17.6","Tissue RNA - cerebellum [nTPM]":"27.2","Tissue RNA - cerebral cortex [nTPM]":"23.7","Tissue RNA - cervix [nTPM]":"14.6","Tissue RNA - choroid plexus [nTPM]":"16.8","Tissue RNA - colon [nTPM]":"15.5","Tissue RNA - duodenum [nTPM]":"11.3","Tissue RNA - endometrium 1 [nTPM]":"30.5","Tissue RNA - epididymis [nTPM]":"15.4","Tissue RNA - esophagus [nTPM]":"16.0","Tissue RNA - fallopian tube [nTPM]":"16.1","Tissue RNA - gallbladder [nTPM]":"17.0","Tissue RNA - heart muscle [nTPM]":"17.7","Tissue RNA - hippocampal formation [nTPM]":"21.2","Tissue RNA - hypothalamus [nTPM]":"22.0","Tissue RNA - kidney [nTPM]":"13.4","Tissue RNA - liver [nTPM]":"21.3","Tissue RNA - lung [nTPM]":"16.9","Tissue RNA - lymph node [nTPM]":"16.9","Tissue RNA - medulla oblongata [nTPM]":"20.3","Tissue RNA - midbrain [nTPM]":"20.2","Tissue RNA - ovary [nTPM]":"17.1","Tissue RNA - pancreas [nTPM]":"14.1","Tissue RNA - parathyroid gland [nTPM]":"17.7","Tissue RNA - pituitary gland [nTPM]":"24.1","Tissue RNA - placenta [nTPM]":"19.0","Tissue RNA - pons [nTPM]":"20.5","Tissue RNA - prostate [nTPM]":"19.8","Tissue RNA - rectum [nTPM]":"12.9","Tissue RNA - retina [nTPM]":"13.1","Tissue RNA - salivary gland [nTPM]":"13.9","Tissue RNA - seminal vesicle [nTPM]":"11.5","Tissue RNA - skeletal muscle [nTPM]":"18.9","Tissue RNA - skin 1 [nTPM]":"19.0","Tissue RNA - small intestine [nTPM]":"11.3","Tissue RNA - smooth muscle [nTPM]":"15.6","Tissue RNA - spinal cord [nTPM]":"18.9","Tissue RNA - spleen [nTPM]":"15.7","Tissue RNA - stomach 1 [nTPM]":"15.2","Tissue RNA - testis [nTPM]":"8.9","Tissue RNA - thalamus [nTPM]":"22.1","Tissue RNA - thymus [nTPM]":"13.1","Tissue RNA - thyroid gland [nTPM]":"21.8","Tissue RNA - tongue [nTPM]":"11.0","Tissue RNA - tonsil [nTPM]":"11.6","Tissue RNA - urinary bladder [nTPM]":"17.2","Tissue RNA - vagina [nTPM]":"12.4","Tissue RNA - white matter [nTPM]":"28.9","Cell RNA - A-431 [nTPM]":"37.1","Cell RNA - A549 [nTPM]":"17.5","Cell RNA - AF22 [nTPM]":"30.3","Cell RNA - AN3-CA [nTPM]":"46.3","Cell RNA - ASC diff [nTPM]":"49.0","Cell RNA - ASC TERT1 [nTPM]":"81.7","Cell RNA - BEWO [nTPM]":"28.9","Cell RNA - BJ [nTPM]":"51.0","Cell RNA - BJ hTERT+ [nTPM]":"58.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"40.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"40.0","Cell RNA - CACO-2 [nTPM]":"25.2","Cell RNA - CAPAN-2 [nTPM]":"15.6","Cell RNA - Daudi [nTPM]":"19.6","Cell RNA - EFO-21 [nTPM]":"25.9","Cell RNA - fHDF\/TERT166 [nTPM]":"69.3","Cell RNA - GAMG [nTPM]":"54.7","Cell RNA - HaCaT [nTPM]":"38.6","Cell RNA - HAP1 [nTPM]":"41.1","Cell RNA - HBEC3-KT [nTPM]":"61.4","Cell RNA - HBF TERT88 [nTPM]":"56.6","Cell RNA - HDLM-2 [nTPM]":"92.8","Cell RNA - HEK 293 [nTPM]":"20.4","Cell RNA - HEL [nTPM]":"41.6","Cell RNA - HeLa [nTPM]":"30.8","Cell RNA - Hep G2 [nTPM]":"30.7","Cell RNA - HHSteC [nTPM]":"42.1","Cell RNA - HL-60 [nTPM]":"25.6","Cell RNA - HMC-1 [nTPM]":"27.8","Cell RNA - HSkMC [nTPM]":"65.3","Cell RNA - hTCEpi [nTPM]":"41.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"39.0","Cell RNA - hTERT-HME1 [nTPM]":"69.8","Cell RNA - hTERT-RPE1 [nTPM]":"57.3","Cell RNA - HUVEC TERT2 [nTPM]":"58.0","Cell RNA - JURKAT [nTPM]":"40.5","Cell RNA - K-562 [nTPM]":"31.3","Cell RNA - Karpas-707 [nTPM]":"18.1","Cell RNA - LHCN-M2 [nTPM]":"81.7","Cell RNA - MCF7 [nTPM]":"12.3","Cell RNA - MOLT-4 [nTPM]":"21.7","Cell RNA - NB-4 [nTPM]":"34.6","Cell RNA - NTERA-2 [nTPM]":"18.8","Cell RNA - OE19 [nTPM]":"32.8","Cell RNA - PC-3 [nTPM]":"38.2","Cell RNA - REH [nTPM]":"25.4","Cell RNA - RH-30 [nTPM]":"42.2","Cell RNA - RPMI-8226 [nTPM]":"33.1","Cell RNA - RPTEC TERT1 [nTPM]":"51.4","Cell RNA - RT4 [nTPM]":"24.7","Cell RNA - SCLC-21H [nTPM]":"16.1","Cell RNA - SH-SY5Y [nTPM]":"24.4","Cell RNA - SiHa [nTPM]":"36.4","Cell RNA - SK-BR-3 [nTPM]":"22.2","Cell RNA - SK-MEL-30 [nTPM]":"32.3","Cell RNA - SuSa [nTPM]":"29.5","Cell RNA - T-47d [nTPM]":"30.7","Cell RNA - THP-1 [nTPM]":"43.4","Cell RNA - TIME [nTPM]":"61.6","Cell RNA - U-138 MG [nTPM]":"54.3","Cell RNA - U-2 OS [nTPM]":"40.9","Cell RNA - U-2197 [nTPM]":"27.3","Cell RNA - U-251 MG [nTPM]":"33.6","Cell RNA - U-266\/70 [nTPM]":"24.6","Cell RNA - U-266\/84 [nTPM]":"47.8","Cell RNA - U-698 [nTPM]":"6.0","Cell RNA - U-87 MG [nTPM]":"38.1","Cell RNA - U-937 [nTPM]":"34.4","Cell RNA - WM-115 [nTPM]":"77.4","Blood RNA - basophil [nTPM]":"11.6","Blood RNA - classical monocyte [nTPM]":"10.8","Blood RNA - eosinophil [nTPM]":"8.6","Blood RNA - gdT-cell [nTPM]":"6.8","Blood RNA - intermediate monocyte [nTPM]":"14.1","Blood RNA - MAIT T-cell [nTPM]":"5.7","Blood RNA - memory B-cell [nTPM]":"7.1","Blood RNA - memory CD4 T-cell [nTPM]":"7.6","Blood RNA - memory CD8 T-cell [nTPM]":"7.9","Blood RNA - myeloid DC [nTPM]":"17.6","Blood RNA - naive B-cell [nTPM]":"9.2","Blood RNA - naive CD4 T-cell [nTPM]":"8.3","Blood RNA - naive CD8 T-cell [nTPM]":"8.2","Blood RNA - neutrophil [nTPM]":"3.3","Blood RNA - NK-cell [nTPM]":"8.5","Blood RNA - non-classical monocyte [nTPM]":"20.5","Blood RNA - plasmacytoid DC [nTPM]":"66.5","Blood RNA - T-reg [nTPM]":"5.8","Blood RNA - total PBMC [nTPM]":"4.9","Brain RNA - amygdala [nTPM]":"21.5","Brain RNA - basal ganglia [nTPM]":"22.4","Brain RNA - cerebellum [nTPM]":"27.2","Brain RNA - cerebral cortex [nTPM]":"23.7","Brain RNA - hippocampal formation [nTPM]":"21.2","Brain RNA - hypothalamus [nTPM]":"22.0","Brain RNA - medulla oblongata [nTPM]":"20.3","Brain RNA - midbrain [nTPM]":"20.2","Brain RNA - pons [nTPM]":"20.5","Brain RNA - spinal cord [nTPM]":"18.9","Brain RNA - thalamus [nTPM]":"22.1","Brain RNA - white matter [nTPM]":"28.9","Single Cell Type RNA - Adipocytes [nTPM]":"47.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.1","Single Cell Type RNA - Astrocytes [nTPM]":"28.7","Single Cell Type RNA - B-cells [nTPM]":"29.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"43.3","Single Cell Type RNA - Bipolar cells [nTPM]":"29.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"45.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"45.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"32.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"21.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"37.5","Single Cell Type RNA - dendritic cells [nTPM]":"32.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"21.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"23.7","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"52.7","Single Cell Type RNA - Endothelial cells [nTPM]":"35.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.4","Single Cell Type RNA - Erythroid cells [nTPM]":"37.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"42.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"34.8","Single Cell Type RNA - Fibroblasts [nTPM]":"36.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"27.0","Single Cell Type RNA - granulocytes [nTPM]":"24.1","Single Cell Type RNA - Granulosa cells [nTPM]":"35.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.9","Single Cell Type RNA - Hepatocytes [nTPM]":"27.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.7","Single Cell Type RNA - Horizontal cells [nTPM]":"28.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"53.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"25.9","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"33.7","Single Cell Type RNA - Langerhans cells [nTPM]":"55.4","Single Cell Type RNA - Late spermatids [nTPM]":"4.3","Single Cell Type RNA - Leydig cells [nTPM]":"42.3","Single Cell Type RNA - Macrophages [nTPM]":"52.1","Single Cell Type RNA - Melanocytes [nTPM]":"32.0","Single Cell Type RNA - Microglial cells [nTPM]":"29.0","Single Cell Type RNA - monocytes [nTPM]":"41.1","Single Cell Type RNA - Muller glia cells [nTPM]":"30.4","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"30.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"26.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"47.6","Single Cell Type RNA - Paneth cells [nTPM]":"16.2","Single Cell Type RNA - Peritubular cells [nTPM]":"39.9","Single Cell Type RNA - Plasma cells [nTPM]":"115.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.9","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"43.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"35.6","Single Cell Type RNA - Spermatocytes [nTPM]":"8.6","Single Cell Type RNA - Spermatogonia [nTPM]":"29.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"47.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.2","Single Cell Type RNA - T-cells [nTPM]":"18.2","Single Cell Type RNA - Theca cells [nTPM]":"64.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"29.6","Single Cell Type RNA - Urothelial cells [nTPM]":"18.4"},{"Gene":"EIF2S3","Gene synonym":["EIF2","EIF2G","EIF2gamma"],"Ensembl":"ENSG00000130741","Gene description":"Eukaryotic translation initiation factor 2 subunit gamma","Uniprot":["P41091"],"Chromosome":"X","Position":"24054946-24078810","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Hydrolase","Initiation factor"],"Disease involvement":["Disease variant","Epilepsy","Mental retardation","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB012471"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 32: Non-specific - Translation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB012471":"AB_873547"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.05e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.44e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Tissue RNA - adipose tissue [nTPM]":"65.5","Tissue RNA - adrenal gland [nTPM]":"51.8","Tissue RNA - amygdala [nTPM]":"31.9","Tissue RNA - appendix [nTPM]":"71.8","Tissue RNA - basal ganglia [nTPM]":"33.5","Tissue RNA - bone marrow [nTPM]":"76.2","Tissue RNA - breast [nTPM]":"82.9","Tissue RNA - cerebellum [nTPM]":"35.7","Tissue RNA - cerebral cortex [nTPM]":"35.4","Tissue RNA - cervix [nTPM]":"78.0","Tissue RNA - choroid plexus [nTPM]":"42.5","Tissue RNA - colon [nTPM]":"67.2","Tissue RNA - duodenum [nTPM]":"66.4","Tissue RNA - endometrium 1 [nTPM]":"83.8","Tissue RNA - epididymis [nTPM]":"45.0","Tissue RNA - esophagus [nTPM]":"62.5","Tissue RNA - fallopian tube [nTPM]":"79.9","Tissue RNA - gallbladder [nTPM]":"53.3","Tissue RNA - heart muscle [nTPM]":"57.1","Tissue RNA - hippocampal formation [nTPM]":"31.4","Tissue RNA - hypothalamus [nTPM]":"33.0","Tissue RNA - kidney [nTPM]":"69.6","Tissue RNA - liver [nTPM]":"74.6","Tissue RNA - lung [nTPM]":"50.7","Tissue RNA - lymph node [nTPM]":"113.3","Tissue RNA - medulla oblongata [nTPM]":"35.9","Tissue RNA - midbrain [nTPM]":"32.2","Tissue RNA - ovary [nTPM]":"131.3","Tissue RNA - pancreas [nTPM]":"94.8","Tissue RNA - parathyroid gland [nTPM]":"49.6","Tissue RNA - pituitary gland [nTPM]":"30.1","Tissue RNA - placenta [nTPM]":"46.4","Tissue RNA - pons [nTPM]":"35.7","Tissue RNA - prostate [nTPM]":"51.7","Tissue RNA - rectum [nTPM]":"66.3","Tissue RNA - retina [nTPM]":"46.9","Tissue RNA - salivary gland [nTPM]":"69.7","Tissue RNA - seminal vesicle [nTPM]":"41.7","Tissue RNA - skeletal muscle [nTPM]":"66.7","Tissue RNA - skin 1 [nTPM]":"71.8","Tissue RNA - small intestine [nTPM]":"53.0","Tissue RNA - smooth muscle [nTPM]":"74.3","Tissue RNA - spinal cord [nTPM]":"35.8","Tissue RNA - spleen [nTPM]":"72.1","Tissue RNA - stomach 1 [nTPM]":"66.7","Tissue RNA - testis [nTPM]":"18.6","Tissue RNA - thalamus [nTPM]":"34.8","Tissue RNA - thymus [nTPM]":"97.6","Tissue RNA - thyroid gland [nTPM]":"69.9","Tissue RNA - tongue [nTPM]":"51.8","Tissue RNA - tonsil [nTPM]":"111.6","Tissue RNA - urinary bladder [nTPM]":"66.4","Tissue RNA - vagina [nTPM]":"65.6","Tissue RNA - white matter [nTPM]":"41.4","Cell RNA - A-431 [nTPM]":"261.0","Cell RNA - A549 [nTPM]":"256.0","Cell RNA - AF22 [nTPM]":"110.3","Cell RNA - AN3-CA [nTPM]":"182.7","Cell RNA - ASC diff [nTPM]":"113.5","Cell RNA - ASC TERT1 [nTPM]":"235.5","Cell RNA - BEWO [nTPM]":"73.2","Cell RNA - BJ [nTPM]":"142.3","Cell RNA - BJ hTERT+ [nTPM]":"127.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"114.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"130.6","Cell RNA - CACO-2 [nTPM]":"290.8","Cell RNA - CAPAN-2 [nTPM]":"174.3","Cell RNA - Daudi [nTPM]":"449.5","Cell RNA - EFO-21 [nTPM]":"141.0","Cell RNA - fHDF\/TERT166 [nTPM]":"104.9","Cell RNA - GAMG [nTPM]":"251.9","Cell RNA - HaCaT [nTPM]":"165.1","Cell RNA - HAP1 [nTPM]":"344.7","Cell RNA - HBEC3-KT [nTPM]":"271.3","Cell RNA - HBF TERT88 [nTPM]":"140.8","Cell RNA - HDLM-2 [nTPM]":"147.8","Cell RNA - HEK 293 [nTPM]":"203.7","Cell RNA - HEL [nTPM]":"177.2","Cell RNA - HeLa [nTPM]":"467.8","Cell RNA - Hep G2 [nTPM]":"164.3","Cell RNA - HHSteC [nTPM]":"126.2","Cell RNA - HL-60 [nTPM]":"304.0","Cell RNA - HMC-1 [nTPM]":"219.4","Cell RNA - HSkMC [nTPM]":"206.9","Cell RNA - hTCEpi [nTPM]":"169.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"129.6","Cell RNA - hTERT-HME1 [nTPM]":"269.7","Cell RNA - hTERT-RPE1 [nTPM]":"152.9","Cell RNA - HUVEC TERT2 [nTPM]":"166.2","Cell RNA - JURKAT [nTPM]":"176.0","Cell RNA - K-562 [nTPM]":"275.4","Cell RNA - Karpas-707 [nTPM]":"176.0","Cell RNA - LHCN-M2 [nTPM]":"127.7","Cell RNA - MCF7 [nTPM]":"124.8","Cell RNA - MOLT-4 [nTPM]":"170.6","Cell RNA - NB-4 [nTPM]":"278.8","Cell RNA - NTERA-2 [nTPM]":"268.2","Cell RNA - OE19 [nTPM]":"118.1","Cell RNA - PC-3 [nTPM]":"146.5","Cell RNA - REH [nTPM]":"169.5","Cell RNA - RH-30 [nTPM]":"215.2","Cell RNA - RPMI-8226 [nTPM]":"271.4","Cell RNA - RPTEC TERT1 [nTPM]":"155.4","Cell RNA - RT4 [nTPM]":"241.5","Cell RNA - SCLC-21H [nTPM]":"60.2","Cell RNA - SH-SY5Y [nTPM]":"130.8","Cell RNA - SiHa [nTPM]":"232.3","Cell RNA - SK-BR-3 [nTPM]":"224.7","Cell RNA - SK-MEL-30 [nTPM]":"239.8","Cell RNA - SuSa [nTPM]":"205.5","Cell RNA - T-47d [nTPM]":"289.6","Cell RNA - THP-1 [nTPM]":"205.1","Cell RNA - TIME [nTPM]":"140.2","Cell RNA - U-138 MG [nTPM]":"97.1","Cell RNA - U-2 OS [nTPM]":"66.7","Cell RNA - U-2197 [nTPM]":"177.3","Cell RNA - U-251 MG [nTPM]":"125.3","Cell RNA - U-266\/70 [nTPM]":"156.6","Cell RNA - U-266\/84 [nTPM]":"322.4","Cell RNA - U-698 [nTPM]":"240.9","Cell RNA - U-87 MG [nTPM]":"120.9","Cell RNA - U-937 [nTPM]":"193.1","Cell RNA - WM-115 [nTPM]":"113.7","Blood RNA - basophil [nTPM]":"64.4","Blood RNA - classical monocyte [nTPM]":"141.1","Blood RNA - eosinophil [nTPM]":"27.9","Blood RNA - gdT-cell [nTPM]":"84.9","Blood RNA - intermediate monocyte [nTPM]":"151.9","Blood RNA - MAIT T-cell [nTPM]":"147.8","Blood RNA - memory B-cell [nTPM]":"156.0","Blood RNA - memory CD4 T-cell [nTPM]":"148.8","Blood RNA - memory CD8 T-cell [nTPM]":"113.9","Blood RNA - myeloid DC [nTPM]":"123.9","Blood RNA - naive B-cell [nTPM]":"120.6","Blood RNA - naive CD4 T-cell [nTPM]":"187.5","Blood RNA - naive CD8 T-cell [nTPM]":"156.6","Blood RNA - neutrophil [nTPM]":"51.2","Blood RNA - NK-cell [nTPM]":"106.3","Blood RNA - non-classical monocyte [nTPM]":"132.6","Blood RNA - plasmacytoid DC [nTPM]":"97.4","Blood RNA - T-reg [nTPM]":"124.2","Blood RNA - total PBMC [nTPM]":"127.2","Brain RNA - amygdala [nTPM]":"31.9","Brain RNA - basal ganglia [nTPM]":"33.5","Brain RNA - cerebellum [nTPM]":"35.7","Brain RNA - cerebral cortex [nTPM]":"35.4","Brain RNA - hippocampal formation [nTPM]":"31.4","Brain RNA - hypothalamus [nTPM]":"33.0","Brain RNA - medulla oblongata [nTPM]":"35.9","Brain RNA - midbrain [nTPM]":"32.2","Brain RNA - pons [nTPM]":"35.7","Brain RNA - spinal cord [nTPM]":"35.8","Brain RNA - thalamus [nTPM]":"34.8","Brain RNA - white matter [nTPM]":"41.4","Single Cell Type RNA - Adipocytes [nTPM]":"76.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"54.5","Single Cell Type RNA - Astrocytes [nTPM]":"48.0","Single Cell Type RNA - B-cells [nTPM]":"187.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"126.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"98.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"51.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"145.1","Single Cell Type RNA - Bipolar cells [nTPM]":"25.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"128.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"91.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"49.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"74.4","Single Cell Type RNA - Club cells [nTPM]":"49.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"59.6","Single Cell Type RNA - dendritic cells [nTPM]":"127.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"35.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"111.6","Single Cell Type RNA - Ductal cells [nTPM]":"67.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"67.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"109.4","Single Cell Type RNA - Endothelial cells [nTPM]":"67.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"44.9","Single Cell Type RNA - Erythroid cells [nTPM]":"92.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"57.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"122.1","Single Cell Type RNA - Fibroblasts [nTPM]":"72.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"78.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"90.9","Single Cell Type RNA - granulocytes [nTPM]":"100.8","Single Cell Type RNA - Granulosa cells [nTPM]":"84.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"84.3","Single Cell Type RNA - Hepatocytes [nTPM]":"58.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"89.1","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"65.0","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"138.9","Single Cell Type RNA - Langerhans cells [nTPM]":"91.9","Single Cell Type RNA - Late spermatids [nTPM]":"3.5","Single Cell Type RNA - Leydig cells [nTPM]":"67.7","Single Cell Type RNA - Macrophages [nTPM]":"109.7","Single Cell Type RNA - Melanocytes [nTPM]":"55.2","Single Cell Type RNA - Microglial cells [nTPM]":"36.5","Single Cell Type RNA - monocytes [nTPM]":"134.5","Single Cell Type RNA - Muller glia cells [nTPM]":"30.4","Single Cell Type RNA - NK-cells [nTPM]":"78.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"23.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"31.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"59.5","Single Cell Type RNA - Paneth cells [nTPM]":"68.9","Single Cell Type RNA - Peritubular cells [nTPM]":"61.3","Single Cell Type RNA - Plasma cells [nTPM]":"99.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"70.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"72.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"135.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"40.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Sertoli cells [nTPM]":"72.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"85.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"87.4","Single Cell Type RNA - Spermatocytes [nTPM]":"10.2","Single Cell Type RNA - Spermatogonia [nTPM]":"21.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"130.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"151.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"71.0","Single Cell Type RNA - T-cells [nTPM]":"117.9","Single Cell Type RNA - Theca cells [nTPM]":"76.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"100.4","Single Cell Type RNA - Urothelial cells [nTPM]":"92.9"},{"Gene":"EIF3F","Gene synonym":["eIF3-epsilon","eIF3-p47","EIF3S5"],"Ensembl":"ENSG00000175390","Gene description":"Eukaryotic translation initiation factor 3 subunit F","Uniprot":["O00303"],"Chromosome":"11","Position":"7970251-8001862","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis","Ubl conjugation pathway"],"Molecular function":["Hydrolase","Initiation factor","Protease","Thiol protease"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049250"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"83000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 32: Non-specific - Translation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049250":"AB_2680692"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.86e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-2"},"Tissue RNA - adipose tissue [nTPM]":"225.1","Tissue RNA - adrenal gland [nTPM]":"160.8","Tissue RNA - amygdala [nTPM]":"7.8","Tissue RNA - appendix [nTPM]":"10.2","Tissue RNA - basal ganglia [nTPM]":"7.4","Tissue RNA - bone marrow [nTPM]":"21.7","Tissue RNA - breast [nTPM]":"216.8","Tissue RNA - cerebellum [nTPM]":"8.6","Tissue RNA - cerebral cortex [nTPM]":"7.6","Tissue RNA - cervix [nTPM]":"249.1","Tissue RNA - choroid plexus [nTPM]":"5.1","Tissue RNA - colon [nTPM]":"248.9","Tissue RNA - duodenum [nTPM]":"10.5","Tissue RNA - endometrium 1 [nTPM]":"206.8","Tissue RNA - epididymis [nTPM]":"10.1","Tissue RNA - esophagus [nTPM]":"227.3","Tissue RNA - fallopian tube [nTPM]":"213.3","Tissue RNA - gallbladder [nTPM]":"16.7","Tissue RNA - heart muscle [nTPM]":"186.2","Tissue RNA - hippocampal formation [nTPM]":"7.6","Tissue RNA - hypothalamus [nTPM]":"6.6","Tissue RNA - kidney [nTPM]":"165.8","Tissue RNA - liver [nTPM]":"160.3","Tissue RNA - lung [nTPM]":"157.0","Tissue RNA - lymph node [nTPM]":"24.7","Tissue RNA - medulla oblongata [nTPM]":"7.9","Tissue RNA - midbrain [nTPM]":"6.8","Tissue RNA - ovary [nTPM]":"353.9","Tissue RNA - pancreas [nTPM]":"361.3","Tissue RNA - parathyroid gland [nTPM]":"8.0","Tissue RNA - pituitary gland [nTPM]":"126.6","Tissue RNA - placenta [nTPM]":"11.7","Tissue RNA - pons [nTPM]":"7.7","Tissue RNA - prostate [nTPM]":"170.0","Tissue RNA - rectum [nTPM]":"12.6","Tissue RNA - retina [nTPM]":"15.5","Tissue RNA - salivary gland [nTPM]":"175.5","Tissue RNA - seminal vesicle [nTPM]":"12.9","Tissue RNA - skeletal muscle [nTPM]":"374.0","Tissue RNA - skin 1 [nTPM]":"333.1","Tissue RNA - small intestine [nTPM]":"188.6","Tissue RNA - smooth muscle [nTPM]":"21.2","Tissue RNA - spinal cord [nTPM]":"6.7","Tissue RNA - spleen [nTPM]":"201.6","Tissue RNA - stomach 1 [nTPM]":"238.9","Tissue RNA - testis [nTPM]":"132.7","Tissue RNA - thalamus [nTPM]":"7.3","Tissue RNA - thymus [nTPM]":"11.8","Tissue RNA - thyroid gland [nTPM]":"153.7","Tissue RNA - tongue [nTPM]":"12.8","Tissue RNA - tonsil [nTPM]":"25.4","Tissue RNA - urinary bladder [nTPM]":"218.7","Tissue RNA - vagina [nTPM]":"212.9","Tissue RNA - white matter [nTPM]":"8.2","Cell RNA - A-431 [nTPM]":"23.6","Cell RNA - A549 [nTPM]":"9.3","Cell RNA - AF22 [nTPM]":"12.7","Cell RNA - AN3-CA [nTPM]":"11.3","Cell RNA - ASC diff [nTPM]":"23.5","Cell RNA - ASC TERT1 [nTPM]":"52.6","Cell RNA - BEWO [nTPM]":"39.9","Cell RNA - BJ [nTPM]":"16.1","Cell RNA - BJ hTERT+ [nTPM]":"28.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.4","Cell RNA - CACO-2 [nTPM]":"9.6","Cell RNA - CAPAN-2 [nTPM]":"23.0","Cell RNA - Daudi [nTPM]":"70.4","Cell RNA - EFO-21 [nTPM]":"6.7","Cell RNA - fHDF\/TERT166 [nTPM]":"15.7","Cell RNA - GAMG [nTPM]":"9.1","Cell RNA - HaCaT [nTPM]":"12.5","Cell RNA - HAP1 [nTPM]":"9.9","Cell RNA - HBEC3-KT [nTPM]":"27.7","Cell RNA - HBF TERT88 [nTPM]":"20.4","Cell RNA - HDLM-2 [nTPM]":"23.1","Cell RNA - HEK 293 [nTPM]":"32.4","Cell RNA - HEL [nTPM]":"24.8","Cell RNA - HeLa [nTPM]":"9.5","Cell RNA - Hep G2 [nTPM]":"11.1","Cell RNA - HHSteC [nTPM]":"38.7","Cell RNA - HL-60 [nTPM]":"26.9","Cell RNA - HMC-1 [nTPM]":"10.0","Cell RNA - HSkMC [nTPM]":"32.2","Cell RNA - hTCEpi [nTPM]":"32.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.9","Cell RNA - hTERT-HME1 [nTPM]":"18.7","Cell RNA - hTERT-RPE1 [nTPM]":"18.6","Cell RNA - HUVEC TERT2 [nTPM]":"20.7","Cell RNA - JURKAT [nTPM]":"12.6","Cell RNA - K-562 [nTPM]":"21.5","Cell RNA - Karpas-707 [nTPM]":"16.1","Cell RNA - LHCN-M2 [nTPM]":"22.2","Cell RNA - MCF7 [nTPM]":"9.6","Cell RNA - MOLT-4 [nTPM]":"15.8","Cell RNA - NB-4 [nTPM]":"25.5","Cell RNA - NTERA-2 [nTPM]":"13.1","Cell RNA - OE19 [nTPM]":"9.5","Cell RNA - PC-3 [nTPM]":"22.6","Cell RNA - REH [nTPM]":"17.7","Cell RNA - RH-30 [nTPM]":"17.3","Cell RNA - RPMI-8226 [nTPM]":"22.4","Cell RNA - RPTEC TERT1 [nTPM]":"11.0","Cell RNA - RT4 [nTPM]":"15.8","Cell RNA - SCLC-21H [nTPM]":"29.2","Cell RNA - SH-SY5Y [nTPM]":"50.6","Cell RNA - SiHa [nTPM]":"15.2","Cell RNA - SK-BR-3 [nTPM]":"6.7","Cell RNA - SK-MEL-30 [nTPM]":"19.3","Cell RNA - SuSa [nTPM]":"7.7","Cell RNA - T-47d [nTPM]":"11.9","Cell RNA - THP-1 [nTPM]":"18.6","Cell RNA - TIME [nTPM]":"19.3","Cell RNA - U-138 MG [nTPM]":"9.5","Cell RNA - U-2 OS [nTPM]":"11.0","Cell RNA - U-2197 [nTPM]":"6.9","Cell RNA - U-251 MG [nTPM]":"11.7","Cell RNA - U-266\/70 [nTPM]":"11.8","Cell RNA - U-266\/84 [nTPM]":"21.1","Cell RNA - U-698 [nTPM]":"29.0","Cell RNA - U-87 MG [nTPM]":"6.4","Cell RNA - U-937 [nTPM]":"16.8","Cell RNA - WM-115 [nTPM]":"12.6","Blood RNA - basophil [nTPM]":"37.5","Blood RNA - classical monocyte [nTPM]":"92.4","Blood RNA - eosinophil [nTPM]":"41.7","Blood RNA - gdT-cell [nTPM]":"81.5","Blood RNA - intermediate monocyte [nTPM]":"99.7","Blood RNA - MAIT T-cell [nTPM]":"112.1","Blood RNA - memory B-cell [nTPM]":"174.6","Blood RNA - memory CD4 T-cell [nTPM]":"130.5","Blood RNA - memory CD8 T-cell [nTPM]":"96.4","Blood RNA - myeloid DC [nTPM]":"130.9","Blood RNA - naive B-cell [nTPM]":"161.6","Blood RNA - naive CD4 T-cell [nTPM]":"155.4","Blood RNA - naive CD8 T-cell [nTPM]":"114.5","Blood RNA - neutrophil [nTPM]":"11.7","Blood RNA - NK-cell [nTPM]":"95.8","Blood RNA - non-classical monocyte [nTPM]":"93.6","Blood RNA - plasmacytoid DC [nTPM]":"87.7","Blood RNA - T-reg [nTPM]":"177.6","Blood RNA - total PBMC [nTPM]":"246.5","Brain RNA - amygdala [nTPM]":"7.8","Brain RNA - basal ganglia [nTPM]":"7.4","Brain RNA - cerebellum [nTPM]":"8.6","Brain RNA - cerebral cortex [nTPM]":"7.6","Brain RNA - hippocampal formation [nTPM]":"7.6","Brain RNA - hypothalamus [nTPM]":"6.6","Brain RNA - medulla oblongata [nTPM]":"7.9","Brain RNA - midbrain [nTPM]":"6.8","Brain RNA - pons [nTPM]":"7.7","Brain RNA - spinal cord [nTPM]":"6.7","Brain RNA - thalamus [nTPM]":"7.3","Brain RNA - white matter [nTPM]":"8.2","Single Cell Type RNA - Adipocytes [nTPM]":"179.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"109.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"145.4","Single Cell Type RNA - Astrocytes [nTPM]":"11.1","Single Cell Type RNA - B-cells [nTPM]":"355.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"349.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"364.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"411.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"266.9","Single Cell Type RNA - Bipolar cells [nTPM]":"72.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"271.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"285.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"96.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"264.5","Single Cell Type RNA - Club cells [nTPM]":"197.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"79.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"631.3","Single Cell Type RNA - dendritic cells [nTPM]":"283.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"121.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"293.5","Single Cell Type RNA - Ductal cells [nTPM]":"277.0","Single Cell Type RNA - Early spermatids [nTPM]":"424.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"113.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"204.9","Single Cell Type RNA - Endothelial cells [nTPM]":"218.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"210.2","Single Cell Type RNA - Erythroid cells [nTPM]":"221.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"442.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"670.6","Single Cell Type RNA - Fibroblasts [nTPM]":"216.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"139.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"112.1","Single Cell Type RNA - granulocytes [nTPM]":"164.8","Single Cell Type RNA - Granulosa cells [nTPM]":"335.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"256.6","Single Cell Type RNA - Hepatocytes [nTPM]":"170.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"344.2","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"262.0","Single Cell Type RNA - Ionocytes [nTPM]":"140.4","Single Cell Type RNA - Kupffer cells [nTPM]":"423.1","Single Cell Type RNA - Langerhans cells [nTPM]":"398.1","Single Cell Type RNA - Late spermatids [nTPM]":"913.3","Single Cell Type RNA - Leydig cells [nTPM]":"246.0","Single Cell Type RNA - Macrophages [nTPM]":"263.4","Single Cell Type RNA - Melanocytes [nTPM]":"247.3","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"471.1","Single Cell Type RNA - Muller glia cells [nTPM]":"141.5","Single Cell Type RNA - NK-cells [nTPM]":"362.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"322.2","Single Cell Type RNA - Paneth cells [nTPM]":"242.2","Single Cell Type RNA - Peritubular cells [nTPM]":"196.7","Single Cell Type RNA - Plasma cells [nTPM]":"237.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"247.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"312.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"286.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"115.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"87.1","Single Cell Type RNA - Sertoli cells [nTPM]":"98.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"222.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"374.3","Single Cell Type RNA - Spermatocytes [nTPM]":"197.0","Single Cell Type RNA - Spermatogonia [nTPM]":"124.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"358.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"440.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"563.4","Single Cell Type RNA - T-cells [nTPM]":"319.3","Single Cell Type RNA - Theca cells [nTPM]":"264.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"392.2","Single Cell Type RNA - Urothelial cells [nTPM]":"426.0"},{"Gene":"EIF4A3","Gene synonym":["DDX48","EIF4AIII","Fal1","KIAA0111"],"Ensembl":"ENSG00000141543","Gene description":"Eukaryotic translation initiation factor 4A3","Uniprot":["P38919"],"Chromosome":"17","Position":"80134369-80147151","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["mRNA processing","mRNA splicing","mRNA transport","Nonsense-mediated mRNA decay","rRNA processing","Translation regulation","Transport"],"Molecular function":["Helicase","Hydrolase","RNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021878"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"280000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA021878":"AB_1848090"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.57e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.68e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.87e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.78e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-3"},"Tissue RNA - adipose tissue [nTPM]":"65.8","Tissue RNA - adrenal gland [nTPM]":"81.4","Tissue RNA - amygdala [nTPM]":"19.0","Tissue RNA - appendix [nTPM]":"49.1","Tissue RNA - basal ganglia [nTPM]":"21.1","Tissue RNA - bone marrow [nTPM]":"185.8","Tissue RNA - breast [nTPM]":"44.2","Tissue RNA - cerebellum [nTPM]":"21.5","Tissue RNA - cerebral cortex [nTPM]":"27.2","Tissue RNA - cervix [nTPM]":"51.2","Tissue RNA - choroid plexus [nTPM]":"22.8","Tissue RNA - colon [nTPM]":"44.3","Tissue RNA - duodenum [nTPM]":"38.6","Tissue RNA - endometrium 1 [nTPM]":"46.6","Tissue RNA - epididymis [nTPM]":"38.8","Tissue RNA - esophagus [nTPM]":"81.9","Tissue RNA - fallopian tube [nTPM]":"54.7","Tissue RNA - gallbladder [nTPM]":"40.1","Tissue RNA - heart muscle [nTPM]":"38.0","Tissue RNA - hippocampal formation [nTPM]":"22.3","Tissue RNA - hypothalamus [nTPM]":"21.0","Tissue RNA - kidney [nTPM]":"45.1","Tissue RNA - liver [nTPM]":"42.6","Tissue RNA - lung [nTPM]":"44.0","Tissue RNA - lymph node [nTPM]":"67.0","Tissue RNA - medulla oblongata [nTPM]":"19.9","Tissue RNA - midbrain [nTPM]":"19.5","Tissue RNA - ovary [nTPM]":"66.5","Tissue RNA - pancreas [nTPM]":"37.0","Tissue RNA - parathyroid gland [nTPM]":"58.5","Tissue RNA - pituitary gland [nTPM]":"41.1","Tissue RNA - placenta [nTPM]":"52.9","Tissue RNA - pons [nTPM]":"20.3","Tissue RNA - prostate [nTPM]":"38.7","Tissue RNA - rectum [nTPM]":"47.5","Tissue RNA - retina [nTPM]":"32.3","Tissue RNA - salivary gland [nTPM]":"42.4","Tissue RNA - seminal vesicle [nTPM]":"32.6","Tissue RNA - skeletal muscle [nTPM]":"37.3","Tissue RNA - skin 1 [nTPM]":"64.8","Tissue RNA - small intestine [nTPM]":"38.9","Tissue RNA - smooth muscle [nTPM]":"42.6","Tissue RNA - spinal cord [nTPM]":"22.7","Tissue RNA - spleen [nTPM]":"47.6","Tissue RNA - stomach 1 [nTPM]":"41.4","Tissue RNA - testis [nTPM]":"42.8","Tissue RNA - thalamus [nTPM]":"20.0","Tissue RNA - thymus [nTPM]":"78.2","Tissue RNA - thyroid gland [nTPM]":"37.0","Tissue RNA - tongue [nTPM]":"34.9","Tissue RNA - tonsil [nTPM]":"74.7","Tissue RNA - urinary bladder [nTPM]":"83.4","Tissue RNA - vagina [nTPM]":"55.1","Tissue RNA - white matter [nTPM]":"24.7","Cell RNA - A-431 [nTPM]":"237.2","Cell RNA - A549 [nTPM]":"208.9","Cell RNA - AF22 [nTPM]":"140.5","Cell RNA - AN3-CA [nTPM]":"103.8","Cell RNA - ASC diff [nTPM]":"105.5","Cell RNA - ASC TERT1 [nTPM]":"63.2","Cell RNA - BEWO [nTPM]":"114.4","Cell RNA - BJ [nTPM]":"119.3","Cell RNA - BJ hTERT+ [nTPM]":"91.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"177.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"141.4","Cell RNA - CACO-2 [nTPM]":"223.7","Cell RNA - CAPAN-2 [nTPM]":"110.3","Cell RNA - Daudi [nTPM]":"221.4","Cell RNA - EFO-21 [nTPM]":"67.9","Cell RNA - fHDF\/TERT166 [nTPM]":"112.9","Cell RNA - GAMG [nTPM]":"126.4","Cell RNA - HaCaT [nTPM]":"152.2","Cell RNA - HAP1 [nTPM]":"194.9","Cell RNA - HBEC3-KT [nTPM]":"136.2","Cell RNA - HBF TERT88 [nTPM]":"195.0","Cell RNA - HDLM-2 [nTPM]":"71.5","Cell RNA - HEK 293 [nTPM]":"192.3","Cell RNA - HEL [nTPM]":"142.5","Cell RNA - HeLa [nTPM]":"159.3","Cell RNA - Hep G2 [nTPM]":"244.3","Cell RNA - HHSteC [nTPM]":"103.1","Cell RNA - HL-60 [nTPM]":"253.8","Cell RNA - HMC-1 [nTPM]":"133.4","Cell RNA - HSkMC [nTPM]":"98.7","Cell RNA - hTCEpi [nTPM]":"68.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"149.5","Cell RNA - hTERT-HME1 [nTPM]":"119.4","Cell RNA - hTERT-RPE1 [nTPM]":"71.8","Cell RNA - HUVEC TERT2 [nTPM]":"147.2","Cell RNA - JURKAT [nTPM]":"128.7","Cell RNA - K-562 [nTPM]":"189.8","Cell RNA - Karpas-707 [nTPM]":"140.2","Cell RNA - LHCN-M2 [nTPM]":"105.3","Cell RNA - MCF7 [nTPM]":"178.9","Cell RNA - MOLT-4 [nTPM]":"224.8","Cell RNA - NB-4 [nTPM]":"132.8","Cell RNA - NTERA-2 [nTPM]":"145.0","Cell RNA - OE19 [nTPM]":"223.8","Cell RNA - PC-3 [nTPM]":"190.0","Cell RNA - REH [nTPM]":"168.5","Cell RNA - RH-30 [nTPM]":"282.7","Cell RNA - RPMI-8226 [nTPM]":"172.2","Cell RNA - RPTEC TERT1 [nTPM]":"85.8","Cell RNA - RT4 [nTPM]":"196.5","Cell RNA - SCLC-21H [nTPM]":"186.1","Cell RNA - SH-SY5Y [nTPM]":"100.1","Cell RNA - SiHa [nTPM]":"170.9","Cell RNA - SK-BR-3 [nTPM]":"334.2","Cell RNA - SK-MEL-30 [nTPM]":"151.9","Cell RNA - SuSa [nTPM]":"130.1","Cell RNA - T-47d [nTPM]":"219.3","Cell RNA - THP-1 [nTPM]":"166.7","Cell RNA - TIME [nTPM]":"100.5","Cell RNA - U-138 MG [nTPM]":"108.7","Cell RNA - U-2 OS [nTPM]":"138.6","Cell RNA - U-2197 [nTPM]":"159.9","Cell RNA - U-251 MG [nTPM]":"200.3","Cell RNA - U-266\/70 [nTPM]":"104.4","Cell RNA - U-266\/84 [nTPM]":"86.2","Cell RNA - U-698 [nTPM]":"403.2","Cell RNA - U-87 MG [nTPM]":"88.0","Cell RNA - U-937 [nTPM]":"158.7","Cell RNA - WM-115 [nTPM]":"113.3","Blood RNA - basophil [nTPM]":"126.1","Blood RNA - classical monocyte [nTPM]":"167.0","Blood RNA - eosinophil [nTPM]":"137.4","Blood RNA - gdT-cell [nTPM]":"101.1","Blood RNA - intermediate monocyte [nTPM]":"174.6","Blood RNA - MAIT T-cell [nTPM]":"131.2","Blood RNA - memory B-cell [nTPM]":"142.4","Blood RNA - memory CD4 T-cell [nTPM]":"128.2","Blood RNA - memory CD8 T-cell [nTPM]":"119.4","Blood RNA - myeloid DC [nTPM]":"200.0","Blood RNA - naive B-cell [nTPM]":"119.8","Blood RNA - naive CD4 T-cell [nTPM]":"116.9","Blood RNA - naive CD8 T-cell [nTPM]":"115.2","Blood RNA - neutrophil [nTPM]":"98.7","Blood RNA - NK-cell [nTPM]":"132.9","Blood RNA - non-classical monocyte [nTPM]":"143.4","Blood RNA - plasmacytoid DC [nTPM]":"326.0","Blood RNA - T-reg [nTPM]":"158.2","Blood RNA - total PBMC [nTPM]":"232.6","Brain RNA - amygdala [nTPM]":"19.0","Brain RNA - basal ganglia [nTPM]":"21.1","Brain RNA - cerebellum [nTPM]":"21.5","Brain RNA - cerebral cortex [nTPM]":"27.2","Brain RNA - hippocampal formation [nTPM]":"22.3","Brain RNA - hypothalamus [nTPM]":"21.0","Brain RNA - medulla oblongata [nTPM]":"19.9","Brain RNA - midbrain [nTPM]":"19.5","Brain RNA - pons [nTPM]":"20.3","Brain RNA - spinal cord [nTPM]":"22.7","Brain RNA - thalamus [nTPM]":"20.0","Brain RNA - white matter [nTPM]":"24.7","Single Cell Type RNA - Adipocytes [nTPM]":"117.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"48.0","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"135.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"283.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"273.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"212.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"107.0","Single Cell Type RNA - Bipolar cells [nTPM]":"23.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"77.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"109.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"61.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"107.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"140.1","Single Cell Type RNA - dendritic cells [nTPM]":"165.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"75.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"64.6","Single Cell Type RNA - Ductal cells [nTPM]":"85.6","Single Cell Type RNA - Early spermatids [nTPM]":"33.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"132.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"109.2","Single Cell Type RNA - Endothelial cells [nTPM]":"70.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"60.3","Single Cell Type RNA - Erythroid cells [nTPM]":"24.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"115.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"225.1","Single Cell Type RNA - Fibroblasts [nTPM]":"144.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"149.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"248.2","Single Cell Type RNA - granulocytes [nTPM]":"92.6","Single Cell Type RNA - Granulosa cells [nTPM]":"42.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.2","Single Cell Type RNA - Hepatocytes [nTPM]":"27.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"108.5","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"83.2","Single Cell Type RNA - Ionocytes [nTPM]":"89.5","Single Cell Type RNA - Kupffer cells [nTPM]":"63.4","Single Cell Type RNA - Langerhans cells [nTPM]":"255.0","Single Cell Type RNA - Late spermatids [nTPM]":"12.1","Single Cell Type RNA - Leydig cells [nTPM]":"67.1","Single Cell Type RNA - Macrophages [nTPM]":"199.6","Single Cell Type RNA - Melanocytes [nTPM]":"103.2","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"67.9","Single Cell Type RNA - Muller glia cells [nTPM]":"48.6","Single Cell Type RNA - NK-cells [nTPM]":"23.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"86.6","Single Cell Type RNA - Paneth cells [nTPM]":"83.1","Single Cell Type RNA - Peritubular cells [nTPM]":"49.7","Single Cell Type RNA - Plasma cells [nTPM]":"118.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"96.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"47.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"65.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"61.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"32.5","Single Cell Type RNA - Sertoli cells [nTPM]":"85.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"109.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"207.8","Single Cell Type RNA - Spermatocytes [nTPM]":"99.4","Single Cell Type RNA - Spermatogonia [nTPM]":"123.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"77.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"299.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"261.9","Single Cell Type RNA - T-cells [nTPM]":"138.4","Single Cell Type RNA - Theca cells [nTPM]":"98.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"77.7","Single Cell Type RNA - Urothelial cells [nTPM]":"252.5"},{"Gene":"ELAC2","Gene synonym":["FLJ10530","HPC2"],"Ensembl":"ENSG00000006744","Gene description":"ElaC ribonuclease Z 2","Uniprot":["Q9BQ52"],"Chromosome":"17","Position":"12991612-13018065","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["tRNA processing"],"Molecular function":["Endonuclease","Hydrolase","Nuclease"],"Disease involvement":["Disease variant","Primary mitochondrial disease","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SuSa":"394.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019535"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9500","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA019535":"AB_1848106"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.24e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Tissue RNA - adipose tissue [nTPM]":"30.7","Tissue RNA - adrenal gland [nTPM]":"35.8","Tissue RNA - amygdala [nTPM]":"13.7","Tissue RNA - appendix [nTPM]":"23.0","Tissue RNA - basal ganglia [nTPM]":"14.6","Tissue RNA - bone marrow [nTPM]":"22.7","Tissue RNA - breast [nTPM]":"24.6","Tissue RNA - cerebellum [nTPM]":"14.7","Tissue RNA - cerebral cortex [nTPM]":"14.3","Tissue RNA - cervix [nTPM]":"21.7","Tissue RNA - choroid plexus [nTPM]":"18.0","Tissue RNA - colon [nTPM]":"28.7","Tissue RNA - duodenum [nTPM]":"23.1","Tissue RNA - endometrium 1 [nTPM]":"24.7","Tissue RNA - epididymis [nTPM]":"17.1","Tissue RNA - esophagus [nTPM]":"31.9","Tissue RNA - fallopian tube [nTPM]":"25.8","Tissue RNA - gallbladder [nTPM]":"21.1","Tissue RNA - heart muscle [nTPM]":"38.1","Tissue RNA - hippocampal formation [nTPM]":"13.8","Tissue RNA - hypothalamus [nTPM]":"15.0","Tissue RNA - kidney [nTPM]":"28.6","Tissue RNA - liver [nTPM]":"32.5","Tissue RNA - lung [nTPM]":"19.8","Tissue RNA - lymph node [nTPM]":"28.0","Tissue RNA - medulla oblongata [nTPM]":"16.4","Tissue RNA - midbrain [nTPM]":"14.6","Tissue RNA - ovary [nTPM]":"19.8","Tissue RNA - pancreas [nTPM]":"23.1","Tissue RNA - parathyroid gland [nTPM]":"33.8","Tissue RNA - pituitary gland [nTPM]":"12.5","Tissue RNA - placenta [nTPM]":"23.5","Tissue RNA - pons [nTPM]":"15.3","Tissue RNA - prostate [nTPM]":"26.4","Tissue RNA - rectum [nTPM]":"32.7","Tissue RNA - retina [nTPM]":"22.5","Tissue RNA - salivary gland [nTPM]":"20.4","Tissue RNA - seminal vesicle [nTPM]":"33.6","Tissue RNA - skeletal muscle [nTPM]":"60.2","Tissue RNA - skin 1 [nTPM]":"23.8","Tissue RNA - small intestine [nTPM]":"21.1","Tissue RNA - smooth muscle [nTPM]":"33.6","Tissue RNA - spinal cord [nTPM]":"17.1","Tissue RNA - spleen [nTPM]":"28.8","Tissue RNA - stomach 1 [nTPM]":"24.8","Tissue RNA - testis [nTPM]":"28.1","Tissue RNA - thalamus [nTPM]":"13.4","Tissue RNA - thymus [nTPM]":"28.4","Tissue RNA - thyroid gland [nTPM]":"25.8","Tissue RNA - tongue [nTPM]":"35.7","Tissue RNA - tonsil [nTPM]":"37.6","Tissue RNA - urinary bladder [nTPM]":"24.6","Tissue RNA - vagina [nTPM]":"18.2","Tissue RNA - white matter [nTPM]":"22.1","Cell RNA - A-431 [nTPM]":"76.4","Cell RNA - A549 [nTPM]":"102.1","Cell RNA - AF22 [nTPM]":"69.8","Cell RNA - AN3-CA [nTPM]":"81.5","Cell RNA - ASC diff [nTPM]":"53.3","Cell RNA - ASC TERT1 [nTPM]":"53.9","Cell RNA - BEWO [nTPM]":"44.9","Cell RNA - BJ [nTPM]":"75.4","Cell RNA - BJ hTERT+ [nTPM]":"59.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"119.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"79.8","Cell RNA - CACO-2 [nTPM]":"84.3","Cell RNA - CAPAN-2 [nTPM]":"34.8","Cell RNA - Daudi [nTPM]":"127.7","Cell RNA - EFO-21 [nTPM]":"84.9","Cell RNA - fHDF\/TERT166 [nTPM]":"69.9","Cell RNA - GAMG [nTPM]":"45.0","Cell RNA - HaCaT [nTPM]":"96.6","Cell RNA - HAP1 [nTPM]":"133.6","Cell RNA - HBEC3-KT [nTPM]":"80.6","Cell RNA - HBF TERT88 [nTPM]":"113.5","Cell RNA - HDLM-2 [nTPM]":"65.7","Cell RNA - HEK 293 [nTPM]":"163.7","Cell RNA - HEL [nTPM]":"73.0","Cell RNA - HeLa [nTPM]":"82.1","Cell RNA - Hep G2 [nTPM]":"54.7","Cell RNA - HHSteC [nTPM]":"40.7","Cell RNA - HL-60 [nTPM]":"64.7","Cell RNA - HMC-1 [nTPM]":"99.4","Cell RNA - HSkMC [nTPM]":"47.3","Cell RNA - hTCEpi [nTPM]":"70.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"88.2","Cell RNA - hTERT-HME1 [nTPM]":"80.5","Cell RNA - hTERT-RPE1 [nTPM]":"51.4","Cell RNA - HUVEC TERT2 [nTPM]":"88.3","Cell RNA - JURKAT [nTPM]":"71.5","Cell RNA - K-562 [nTPM]":"108.0","Cell RNA - Karpas-707 [nTPM]":"34.8","Cell RNA - LHCN-M2 [nTPM]":"88.7","Cell RNA - MCF7 [nTPM]":"58.0","Cell RNA - MOLT-4 [nTPM]":"112.0","Cell RNA - NB-4 [nTPM]":"58.3","Cell RNA - NTERA-2 [nTPM]":"62.2","Cell RNA - OE19 [nTPM]":"132.9","Cell RNA - PC-3 [nTPM]":"80.7","Cell RNA - REH [nTPM]":"84.1","Cell RNA - RH-30 [nTPM]":"122.2","Cell RNA - RPMI-8226 [nTPM]":"82.2","Cell RNA - RPTEC TERT1 [nTPM]":"62.0","Cell RNA - RT4 [nTPM]":"59.2","Cell RNA - SCLC-21H [nTPM]":"37.5","Cell RNA - SH-SY5Y [nTPM]":"54.6","Cell RNA - SiHa [nTPM]":"97.4","Cell RNA - SK-BR-3 [nTPM]":"61.0","Cell RNA - SK-MEL-30 [nTPM]":"39.2","Cell RNA - SuSa [nTPM]":"394.4","Cell RNA - T-47d [nTPM]":"59.1","Cell RNA - THP-1 [nTPM]":"26.2","Cell RNA - TIME [nTPM]":"82.7","Cell RNA - U-138 MG [nTPM]":"152.3","Cell RNA - U-2 OS [nTPM]":"47.6","Cell RNA - U-2197 [nTPM]":"57.0","Cell RNA - U-251 MG [nTPM]":"116.3","Cell RNA - U-266\/70 [nTPM]":"24.7","Cell RNA - U-266\/84 [nTPM]":"51.6","Cell RNA - U-698 [nTPM]":"53.3","Cell RNA - U-87 MG [nTPM]":"57.6","Cell RNA - U-937 [nTPM]":"64.2","Cell RNA - WM-115 [nTPM]":"54.6","Blood RNA - basophil [nTPM]":"26.9","Blood RNA - classical monocyte [nTPM]":"31.1","Blood RNA - eosinophil [nTPM]":"19.2","Blood RNA - gdT-cell [nTPM]":"41.6","Blood RNA - intermediate monocyte [nTPM]":"41.2","Blood RNA - MAIT T-cell [nTPM]":"43.4","Blood RNA - memory B-cell [nTPM]":"37.7","Blood RNA - memory CD4 T-cell [nTPM]":"39.1","Blood RNA - memory CD8 T-cell [nTPM]":"40.7","Blood RNA - myeloid DC [nTPM]":"48.4","Blood RNA - naive B-cell [nTPM]":"34.4","Blood RNA - naive CD4 T-cell [nTPM]":"39.7","Blood RNA - naive CD8 T-cell [nTPM]":"36.2","Blood RNA - neutrophil [nTPM]":"4.7","Blood RNA - NK-cell [nTPM]":"53.5","Blood RNA - non-classical monocyte [nTPM]":"46.8","Blood RNA - plasmacytoid DC [nTPM]":"30.1","Blood RNA - T-reg [nTPM]":"53.4","Blood RNA - total PBMC [nTPM]":"46.3","Brain RNA - amygdala [nTPM]":"13.7","Brain RNA - basal ganglia [nTPM]":"14.6","Brain RNA - cerebellum [nTPM]":"14.7","Brain RNA - cerebral cortex [nTPM]":"14.3","Brain RNA - hippocampal formation [nTPM]":"13.8","Brain RNA - hypothalamus [nTPM]":"15.0","Brain RNA - medulla oblongata [nTPM]":"16.4","Brain RNA - midbrain [nTPM]":"14.6","Brain RNA - pons [nTPM]":"15.3","Brain RNA - spinal cord [nTPM]":"17.1","Brain RNA - thalamus [nTPM]":"13.4","Brain RNA - white matter [nTPM]":"22.1","Single Cell Type RNA - Adipocytes [nTPM]":"11.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.8","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"18.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"16.5","Single Cell Type RNA - Bipolar cells [nTPM]":"11.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"28.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"12.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"59.3","Single Cell Type RNA - dendritic cells [nTPM]":"15.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"27.4","Single Cell Type RNA - Early spermatids [nTPM]":"6.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.1","Single Cell Type RNA - Endothelial cells [nTPM]":"14.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"24.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"32.6","Single Cell Type RNA - Fibroblasts [nTPM]":"16.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.2","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"30.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"28.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.2","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.5","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"14.2","Single Cell Type RNA - Langerhans cells [nTPM]":"7.0","Single Cell Type RNA - Late spermatids [nTPM]":"5.7","Single Cell Type RNA - Leydig cells [nTPM]":"10.5","Single Cell Type RNA - Macrophages [nTPM]":"10.0","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"14.7","Single Cell Type RNA - Muller glia cells [nTPM]":"16.1","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"25.9","Single Cell Type RNA - Paneth cells [nTPM]":"16.6","Single Cell Type RNA - Peritubular cells [nTPM]":"21.4","Single Cell Type RNA - Plasma cells [nTPM]":"21.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.9","Single Cell Type RNA - Spermatocytes [nTPM]":"26.4","Single Cell Type RNA - Spermatogonia [nTPM]":"24.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"33.5","Single Cell Type RNA - T-cells [nTPM]":"15.9","Single Cell Type RNA - Theca cells [nTPM]":"59.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.7","Single Cell Type RNA - Urothelial cells [nTPM]":"8.2"},{"Gene":"ELOVL1","Gene synonym":["Ssc1"],"Ensembl":"ENSG00000066322","Gene description":"ELOVL fatty acid elongase 1","Uniprot":["Q9BW60"],"Chromosome":"1","Position":"43363398-43368074","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033426","HPA056557"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 30: Mammary glandular cells - Lactation","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB033426":"AB_2099896","HPA056557":"AB_2683173"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.63e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.79e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.51e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-2"},"Tissue RNA - adipose tissue [nTPM]":"78.5","Tissue RNA - adrenal gland [nTPM]":"54.7","Tissue RNA - amygdala [nTPM]":"77.2","Tissue RNA - appendix [nTPM]":"39.8","Tissue RNA - basal ganglia [nTPM]":"115.6","Tissue RNA - bone marrow [nTPM]":"52.9","Tissue RNA - breast [nTPM]":"66.6","Tissue RNA - cerebellum [nTPM]":"121.1","Tissue RNA - cerebral cortex [nTPM]":"116.9","Tissue RNA - cervix [nTPM]":"57.1","Tissue RNA - choroid plexus [nTPM]":"61.4","Tissue RNA - colon [nTPM]":"63.9","Tissue RNA - duodenum [nTPM]":"51.6","Tissue RNA - endometrium 1 [nTPM]":"46.5","Tissue RNA - epididymis [nTPM]":"30.6","Tissue RNA - esophagus [nTPM]":"176.6","Tissue RNA - fallopian tube [nTPM]":"38.9","Tissue RNA - gallbladder [nTPM]":"42.4","Tissue RNA - heart muscle [nTPM]":"47.2","Tissue RNA - hippocampal formation [nTPM]":"76.8","Tissue RNA - hypothalamus [nTPM]":"93.2","Tissue RNA - kidney [nTPM]":"59.7","Tissue RNA - liver [nTPM]":"45.8","Tissue RNA - lung [nTPM]":"59.6","Tissue RNA - lymph node [nTPM]":"40.1","Tissue RNA - medulla oblongata [nTPM]":"152.0","Tissue RNA - midbrain [nTPM]":"110.1","Tissue RNA - ovary [nTPM]":"28.9","Tissue RNA - pancreas [nTPM]":"55.4","Tissue RNA - parathyroid gland [nTPM]":"46.2","Tissue RNA - pituitary gland [nTPM]":"27.2","Tissue RNA - placenta [nTPM]":"51.0","Tissue RNA - pons [nTPM]":"140.7","Tissue RNA - prostate [nTPM]":"58.7","Tissue RNA - rectum [nTPM]":"48.6","Tissue RNA - retina [nTPM]":"8.4","Tissue RNA - salivary gland [nTPM]":"72.7","Tissue RNA - seminal vesicle [nTPM]":"48.8","Tissue RNA - skeletal muscle [nTPM]":"24.1","Tissue RNA - skin 1 [nTPM]":"201.9","Tissue RNA - small intestine [nTPM]":"55.4","Tissue RNA - smooth muscle [nTPM]":"50.8","Tissue RNA - spinal cord [nTPM]":"114.8","Tissue RNA - spleen [nTPM]":"57.1","Tissue RNA - stomach 1 [nTPM]":"70.6","Tissue RNA - testis [nTPM]":"18.6","Tissue RNA - thalamus [nTPM]":"107.7","Tissue RNA - thymus [nTPM]":"22.2","Tissue RNA - thyroid gland [nTPM]":"66.8","Tissue RNA - tongue [nTPM]":"28.0","Tissue RNA - tonsil [nTPM]":"55.7","Tissue RNA - urinary bladder [nTPM]":"68.5","Tissue RNA - vagina [nTPM]":"86.8","Tissue RNA - white matter [nTPM]":"165.7","Cell RNA - A-431 [nTPM]":"108.0","Cell RNA - A549 [nTPM]":"119.5","Cell RNA - AF22 [nTPM]":"22.6","Cell RNA - AN3-CA [nTPM]":"44.8","Cell RNA - ASC diff [nTPM]":"148.4","Cell RNA - ASC TERT1 [nTPM]":"138.2","Cell RNA - BEWO [nTPM]":"70.2","Cell RNA - BJ [nTPM]":"125.2","Cell RNA - BJ hTERT+ [nTPM]":"154.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"153.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"122.4","Cell RNA - CACO-2 [nTPM]":"105.9","Cell RNA - CAPAN-2 [nTPM]":"182.5","Cell RNA - Daudi [nTPM]":"73.9","Cell RNA - EFO-21 [nTPM]":"94.3","Cell RNA - fHDF\/TERT166 [nTPM]":"193.6","Cell RNA - GAMG [nTPM]":"130.3","Cell RNA - HaCaT [nTPM]":"119.4","Cell RNA - HAP1 [nTPM]":"79.7","Cell RNA - HBEC3-KT [nTPM]":"152.2","Cell RNA - HBF TERT88 [nTPM]":"93.2","Cell RNA - HDLM-2 [nTPM]":"94.6","Cell RNA - HEK 293 [nTPM]":"53.9","Cell RNA - HEL [nTPM]":"96.6","Cell RNA - HeLa [nTPM]":"77.3","Cell RNA - Hep G2 [nTPM]":"77.1","Cell RNA - HHSteC [nTPM]":"128.2","Cell RNA - HL-60 [nTPM]":"84.2","Cell RNA - HMC-1 [nTPM]":"98.0","Cell RNA - HSkMC [nTPM]":"106.2","Cell RNA - hTCEpi [nTPM]":"168.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"180.9","Cell RNA - hTERT-HME1 [nTPM]":"198.4","Cell RNA - hTERT-RPE1 [nTPM]":"114.8","Cell RNA - HUVEC TERT2 [nTPM]":"155.0","Cell RNA - JURKAT [nTPM]":"27.7","Cell RNA - K-562 [nTPM]":"68.1","Cell RNA - Karpas-707 [nTPM]":"54.8","Cell RNA - LHCN-M2 [nTPM]":"178.5","Cell RNA - MCF7 [nTPM]":"79.5","Cell RNA - MOLT-4 [nTPM]":"19.9","Cell RNA - NB-4 [nTPM]":"69.5","Cell RNA - NTERA-2 [nTPM]":"33.5","Cell RNA - OE19 [nTPM]":"136.9","Cell RNA - PC-3 [nTPM]":"120.2","Cell RNA - REH [nTPM]":"43.6","Cell RNA - RH-30 [nTPM]":"59.9","Cell RNA - RPMI-8226 [nTPM]":"89.7","Cell RNA - RPTEC TERT1 [nTPM]":"195.5","Cell RNA - RT4 [nTPM]":"128.7","Cell RNA - SCLC-21H [nTPM]":"27.4","Cell RNA - SH-SY5Y [nTPM]":"28.8","Cell RNA - SiHa [nTPM]":"73.7","Cell RNA - SK-BR-3 [nTPM]":"258.4","Cell RNA - SK-MEL-30 [nTPM]":"105.8","Cell RNA - SuSa [nTPM]":"66.8","Cell RNA - T-47d [nTPM]":"121.2","Cell RNA - THP-1 [nTPM]":"82.4","Cell RNA - TIME [nTPM]":"132.2","Cell RNA - U-138 MG [nTPM]":"129.7","Cell RNA - U-2 OS [nTPM]":"82.5","Cell RNA - U-2197 [nTPM]":"161.2","Cell RNA - U-251 MG [nTPM]":"161.3","Cell RNA - U-266\/70 [nTPM]":"26.6","Cell RNA - U-266\/84 [nTPM]":"31.2","Cell RNA - U-698 [nTPM]":"35.4","Cell RNA - U-87 MG [nTPM]":"127.8","Cell RNA - U-937 [nTPM]":"85.2","Cell RNA - WM-115 [nTPM]":"120.1","Blood RNA - basophil [nTPM]":"134.9","Blood RNA - classical monocyte [nTPM]":"189.6","Blood RNA - eosinophil [nTPM]":"172.7","Blood RNA - gdT-cell [nTPM]":"105.1","Blood RNA - intermediate monocyte [nTPM]":"180.0","Blood RNA - MAIT T-cell [nTPM]":"93.4","Blood RNA - memory B-cell [nTPM]":"109.0","Blood RNA - memory CD4 T-cell [nTPM]":"98.4","Blood RNA - memory CD8 T-cell [nTPM]":"103.2","Blood RNA - myeloid DC [nTPM]":"212.8","Blood RNA - naive B-cell [nTPM]":"94.2","Blood RNA - naive CD4 T-cell [nTPM]":"63.5","Blood RNA - naive CD8 T-cell [nTPM]":"88.0","Blood RNA - neutrophil [nTPM]":"133.0","Blood RNA - NK-cell [nTPM]":"114.7","Blood RNA - non-classical monocyte [nTPM]":"179.6","Blood RNA - plasmacytoid DC [nTPM]":"148.8","Blood RNA - T-reg [nTPM]":"113.8","Blood RNA - total PBMC [nTPM]":"203.1","Brain RNA - amygdala [nTPM]":"77.2","Brain RNA - basal ganglia [nTPM]":"115.6","Brain RNA - cerebellum [nTPM]":"121.1","Brain RNA - cerebral cortex [nTPM]":"116.9","Brain RNA - hippocampal formation [nTPM]":"76.8","Brain RNA - hypothalamus [nTPM]":"93.2","Brain RNA - medulla oblongata [nTPM]":"152.0","Brain RNA - midbrain [nTPM]":"110.1","Brain RNA - pons [nTPM]":"140.7","Brain RNA - spinal cord [nTPM]":"114.8","Brain RNA - thalamus [nTPM]":"107.7","Brain RNA - white matter [nTPM]":"165.7","Single Cell Type RNA - Adipocytes [nTPM]":"44.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.5","Single Cell Type RNA - Astrocytes [nTPM]":"7.5","Single Cell Type RNA - B-cells [nTPM]":"28.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"25.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"61.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"29.6","Single Cell Type RNA - Bipolar cells [nTPM]":"5.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"60.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"37.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"34.3","Single Cell Type RNA - Club cells [nTPM]":"40.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"93.4","Single Cell Type RNA - dendritic cells [nTPM]":"36.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"114.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"91.5","Single Cell Type RNA - Early spermatids [nTPM]":"3.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.3","Single Cell Type RNA - Endothelial cells [nTPM]":"43.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.2","Single Cell Type RNA - Erythroid cells [nTPM]":"67.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"100.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"127.4","Single Cell Type RNA - Fibroblasts [nTPM]":"26.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"48.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"45.2","Single Cell Type RNA - granulocytes [nTPM]":"21.0","Single Cell Type RNA - Granulosa cells [nTPM]":"52.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"24.7","Single Cell Type RNA - Hepatocytes [nTPM]":"16.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"74.9","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"33.8","Single Cell Type RNA - Ionocytes [nTPM]":"46.8","Single Cell Type RNA - Kupffer cells [nTPM]":"46.3","Single Cell Type RNA - Langerhans cells [nTPM]":"37.5","Single Cell Type RNA - Late spermatids [nTPM]":"4.6","Single Cell Type RNA - Leydig cells [nTPM]":"20.2","Single Cell Type RNA - Macrophages [nTPM]":"41.5","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"92.5","Single Cell Type RNA - Muller glia cells [nTPM]":"13.7","Single Cell Type RNA - NK-cells [nTPM]":"32.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"66.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"133.3","Single Cell Type RNA - Paneth cells [nTPM]":"63.9","Single Cell Type RNA - Peritubular cells [nTPM]":"25.6","Single Cell Type RNA - Plasma cells [nTPM]":"19.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"44.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"66.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.5","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"39.7","Single Cell Type RNA - Spermatocytes [nTPM]":"8.4","Single Cell Type RNA - Spermatogonia [nTPM]":"11.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"70.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"31.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"95.9","Single Cell Type RNA - T-cells [nTPM]":"31.5","Single Cell Type RNA - Theca cells [nTPM]":"50.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"47.2","Single Cell Type RNA - Urothelial cells [nTPM]":"49.2"},{"Gene":"ELOVL5","Gene synonym":["dJ483K16.1","HELO1","SCA38"],"Ensembl":"ENSG00000012660","Gene description":"ELOVL fatty acid elongase 5","Uniprot":["Q9NYP7"],"Chromosome":"6","Position":"53267398-53349179","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017042","HPA047752","HPA054197"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 35: Glandular cells - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB017042":null,"HPA047752":"AB_2680147","HPA054197":"AB_2682413"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.94e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.80e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Tissue RNA - adipose tissue [nTPM]":"242.4","Tissue RNA - adrenal gland [nTPM]":"134.7","Tissue RNA - amygdala [nTPM]":"51.3","Tissue RNA - appendix [nTPM]":"74.9","Tissue RNA - basal ganglia [nTPM]":"67.0","Tissue RNA - bone marrow [nTPM]":"114.6","Tissue RNA - breast [nTPM]":"199.2","Tissue RNA - cerebellum [nTPM]":"74.6","Tissue RNA - cerebral cortex [nTPM]":"79.2","Tissue RNA - cervix [nTPM]":"48.9","Tissue RNA - choroid plexus [nTPM]":"49.4","Tissue RNA - colon [nTPM]":"40.0","Tissue RNA - duodenum [nTPM]":"28.3","Tissue RNA - endometrium 1 [nTPM]":"39.8","Tissue RNA - epididymis [nTPM]":"49.7","Tissue RNA - esophagus [nTPM]":"28.4","Tissue RNA - fallopian tube [nTPM]":"46.0","Tissue RNA - gallbladder [nTPM]":"51.3","Tissue RNA - heart muscle [nTPM]":"37.8","Tissue RNA - hippocampal formation [nTPM]":"50.8","Tissue RNA - hypothalamus [nTPM]":"65.3","Tissue RNA - kidney [nTPM]":"38.9","Tissue RNA - liver [nTPM]":"108.9","Tissue RNA - lung [nTPM]":"68.4","Tissue RNA - lymph node [nTPM]":"106.7","Tissue RNA - medulla oblongata [nTPM]":"80.7","Tissue RNA - midbrain [nTPM]":"69.0","Tissue RNA - ovary [nTPM]":"32.3","Tissue RNA - pancreas [nTPM]":"15.4","Tissue RNA - parathyroid gland [nTPM]":"24.3","Tissue RNA - pituitary gland [nTPM]":"28.5","Tissue RNA - placenta [nTPM]":"40.2","Tissue RNA - pons [nTPM]":"74.5","Tissue RNA - prostate [nTPM]":"128.0","Tissue RNA - rectum [nTPM]":"18.3","Tissue RNA - retina [nTPM]":"36.5","Tissue RNA - salivary gland [nTPM]":"24.8","Tissue RNA - seminal vesicle [nTPM]":"103.0","Tissue RNA - skeletal muscle [nTPM]":"9.9","Tissue RNA - skin 1 [nTPM]":"32.9","Tissue RNA - small intestine [nTPM]":"47.5","Tissue RNA - smooth muscle [nTPM]":"52.4","Tissue RNA - spinal cord [nTPM]":"67.7","Tissue RNA - spleen [nTPM]":"56.1","Tissue RNA - stomach 1 [nTPM]":"22.8","Tissue RNA - testis [nTPM]":"82.5","Tissue RNA - thalamus [nTPM]":"65.8","Tissue RNA - thymus [nTPM]":"107.3","Tissue RNA - thyroid gland [nTPM]":"45.1","Tissue RNA - tongue [nTPM]":"19.5","Tissue RNA - tonsil [nTPM]":"102.4","Tissue RNA - urinary bladder [nTPM]":"67.1","Tissue RNA - vagina [nTPM]":"27.0","Tissue RNA - white matter [nTPM]":"98.9","Cell RNA - A-431 [nTPM]":"137.2","Cell RNA - A549 [nTPM]":"98.1","Cell RNA - AF22 [nTPM]":"168.0","Cell RNA - AN3-CA [nTPM]":"309.0","Cell RNA - ASC diff [nTPM]":"436.0","Cell RNA - ASC TERT1 [nTPM]":"250.8","Cell RNA - BEWO [nTPM]":"71.3","Cell RNA - BJ [nTPM]":"155.8","Cell RNA - BJ hTERT+ [nTPM]":"174.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"123.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"171.5","Cell RNA - CACO-2 [nTPM]":"87.4","Cell RNA - CAPAN-2 [nTPM]":"154.5","Cell RNA - Daudi [nTPM]":"154.4","Cell RNA - EFO-21 [nTPM]":"110.3","Cell RNA - fHDF\/TERT166 [nTPM]":"163.3","Cell RNA - GAMG [nTPM]":"193.1","Cell RNA - HaCaT [nTPM]":"78.9","Cell RNA - HAP1 [nTPM]":"168.0","Cell RNA - HBEC3-KT [nTPM]":"142.6","Cell RNA - HBF TERT88 [nTPM]":"183.7","Cell RNA - HDLM-2 [nTPM]":"131.2","Cell RNA - HEK 293 [nTPM]":"117.5","Cell RNA - HEL [nTPM]":"153.1","Cell RNA - HeLa [nTPM]":"85.0","Cell RNA - Hep G2 [nTPM]":"122.9","Cell RNA - HHSteC [nTPM]":"239.0","Cell RNA - HL-60 [nTPM]":"122.2","Cell RNA - HMC-1 [nTPM]":"107.2","Cell RNA - HSkMC [nTPM]":"233.6","Cell RNA - hTCEpi [nTPM]":"109.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"123.6","Cell RNA - hTERT-HME1 [nTPM]":"153.9","Cell RNA - hTERT-RPE1 [nTPM]":"124.5","Cell RNA - HUVEC TERT2 [nTPM]":"139.1","Cell RNA - JURKAT [nTPM]":"301.4","Cell RNA - K-562 [nTPM]":"194.2","Cell RNA - Karpas-707 [nTPM]":"87.3","Cell RNA - LHCN-M2 [nTPM]":"90.3","Cell RNA - MCF7 [nTPM]":"14.9","Cell RNA - MOLT-4 [nTPM]":"364.4","Cell RNA - NB-4 [nTPM]":"107.9","Cell RNA - NTERA-2 [nTPM]":"91.2","Cell RNA - OE19 [nTPM]":"5.2","Cell RNA - PC-3 [nTPM]":"73.6","Cell RNA - REH [nTPM]":"139.9","Cell RNA - RH-30 [nTPM]":"115.3","Cell RNA - RPMI-8226 [nTPM]":"54.3","Cell RNA - RPTEC TERT1 [nTPM]":"232.7","Cell RNA - RT4 [nTPM]":"80.6","Cell RNA - SCLC-21H [nTPM]":"155.7","Cell RNA - SH-SY5Y [nTPM]":"107.1","Cell RNA - SiHa [nTPM]":"129.3","Cell RNA - SK-BR-3 [nTPM]":"66.9","Cell RNA - SK-MEL-30 [nTPM]":"135.2","Cell RNA - SuSa [nTPM]":"108.7","Cell RNA - T-47d [nTPM]":"152.3","Cell RNA - THP-1 [nTPM]":"112.9","Cell RNA - TIME [nTPM]":"133.0","Cell RNA - U-138 MG [nTPM]":"134.7","Cell RNA - U-2 OS [nTPM]":"118.5","Cell RNA - U-2197 [nTPM]":"242.2","Cell RNA - U-251 MG [nTPM]":"208.8","Cell RNA - U-266\/70 [nTPM]":"72.8","Cell RNA - U-266\/84 [nTPM]":"72.1","Cell RNA - U-698 [nTPM]":"116.2","Cell RNA - U-87 MG [nTPM]":"70.2","Cell RNA - U-937 [nTPM]":"173.6","Cell RNA - WM-115 [nTPM]":"97.8","Blood RNA - basophil [nTPM]":"47.6","Blood RNA - classical monocyte [nTPM]":"49.2","Blood RNA - eosinophil [nTPM]":"183.7","Blood RNA - gdT-cell [nTPM]":"34.9","Blood RNA - intermediate monocyte [nTPM]":"34.9","Blood RNA - MAIT T-cell [nTPM]":"56.5","Blood RNA - memory B-cell [nTPM]":"88.4","Blood RNA - memory CD4 T-cell [nTPM]":"58.1","Blood RNA - memory CD8 T-cell [nTPM]":"42.7","Blood RNA - myeloid DC [nTPM]":"77.9","Blood RNA - naive B-cell [nTPM]":"101.5","Blood RNA - naive CD4 T-cell [nTPM]":"27.8","Blood RNA - naive CD8 T-cell [nTPM]":"26.3","Blood RNA - neutrophil [nTPM]":"261.5","Blood RNA - NK-cell [nTPM]":"36.7","Blood RNA - non-classical monocyte [nTPM]":"45.0","Blood RNA - plasmacytoid DC [nTPM]":"20.4","Blood RNA - T-reg [nTPM]":"110.0","Blood RNA - total PBMC [nTPM]":"50.6","Brain RNA - amygdala [nTPM]":"51.3","Brain RNA - basal ganglia [nTPM]":"67.0","Brain RNA - cerebellum [nTPM]":"74.6","Brain RNA - cerebral cortex [nTPM]":"79.2","Brain RNA - hippocampal formation [nTPM]":"50.8","Brain RNA - hypothalamus [nTPM]":"65.3","Brain RNA - medulla oblongata [nTPM]":"80.7","Brain RNA - midbrain [nTPM]":"69.0","Brain RNA - pons [nTPM]":"74.5","Brain RNA - spinal cord [nTPM]":"67.7","Brain RNA - thalamus [nTPM]":"65.8","Brain RNA - white matter [nTPM]":"98.9","Single Cell Type RNA - Adipocytes [nTPM]":"48.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"80.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"50.7","Single Cell Type RNA - Astrocytes [nTPM]":"75.4","Single Cell Type RNA - B-cells [nTPM]":"118.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"52.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"108.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"36.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"44.3","Single Cell Type RNA - Bipolar cells [nTPM]":"11.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"177.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"70.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"23.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"40.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.3","Single Cell Type RNA - dendritic cells [nTPM]":"55.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"34.9","Single Cell Type RNA - Early spermatids [nTPM]":"94.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"37.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"53.2","Single Cell Type RNA - Endothelial cells [nTPM]":"54.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"25.0","Single Cell Type RNA - Erythroid cells [nTPM]":"77.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"36.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"58.2","Single Cell Type RNA - Fibroblasts [nTPM]":"54.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"66.4","Single Cell Type RNA - granulocytes [nTPM]":"99.0","Single Cell Type RNA - Granulosa cells [nTPM]":"28.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"39.3","Single Cell Type RNA - Hepatocytes [nTPM]":"88.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"35.5","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"29.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.6","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"57.3","Single Cell Type RNA - Langerhans cells [nTPM]":"114.6","Single Cell Type RNA - Late spermatids [nTPM]":"181.0","Single Cell Type RNA - Leydig cells [nTPM]":"20.8","Single Cell Type RNA - Macrophages [nTPM]":"55.5","Single Cell Type RNA - Melanocytes [nTPM]":"48.0","Single Cell Type RNA - Microglial cells [nTPM]":"39.4","Single Cell Type RNA - monocytes [nTPM]":"53.5","Single Cell Type RNA - Muller glia cells [nTPM]":"83.2","Single Cell Type RNA - NK-cells [nTPM]":"39.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"49.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"111.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"27.8","Single Cell Type RNA - Paneth cells [nTPM]":"1.4","Single Cell Type RNA - Peritubular cells [nTPM]":"32.0","Single Cell Type RNA - Plasma cells [nTPM]":"45.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"169.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"21.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"48.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"58.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.0","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"77.5","Single Cell Type RNA - Spermatocytes [nTPM]":"27.0","Single Cell Type RNA - Spermatogonia [nTPM]":"18.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"35.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"60.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"31.2","Single Cell Type RNA - T-cells [nTPM]":"97.2","Single Cell Type RNA - Theca cells [nTPM]":"60.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.4","Single Cell Type RNA - Urothelial cells [nTPM]":"73.4"},{"Gene":"EMC1","Gene synonym":["KIAA0090"],"Ensembl":"ENSG00000127463","Gene description":"ER membrane protein complex subunit 1","Uniprot":["Q8N766"],"Chromosome":"1","Position":"19215660-19251527","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"63.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048904"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"14000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA048904":"AB_2680552"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.56e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.43e-4"},"Tissue RNA - adipose tissue [nTPM]":"15.4","Tissue RNA - adrenal gland [nTPM]":"11.2","Tissue RNA - amygdala [nTPM]":"10.1","Tissue RNA - appendix [nTPM]":"11.7","Tissue RNA - basal ganglia [nTPM]":"11.6","Tissue RNA - bone marrow [nTPM]":"9.2","Tissue RNA - breast [nTPM]":"11.1","Tissue RNA - cerebellum [nTPM]":"11.7","Tissue RNA - cerebral cortex [nTPM]":"14.0","Tissue RNA - cervix [nTPM]":"12.2","Tissue RNA - choroid plexus [nTPM]":"2.1","Tissue RNA - colon [nTPM]":"12.8","Tissue RNA - duodenum [nTPM]":"8.7","Tissue RNA - endometrium 1 [nTPM]":"12.2","Tissue RNA - epididymis [nTPM]":"13.1","Tissue RNA - esophagus [nTPM]":"10.7","Tissue RNA - fallopian tube [nTPM]":"12.0","Tissue RNA - gallbladder [nTPM]":"8.2","Tissue RNA - heart muscle [nTPM]":"12.5","Tissue RNA - hippocampal formation [nTPM]":"11.8","Tissue RNA - hypothalamus [nTPM]":"16.0","Tissue RNA - kidney [nTPM]":"10.8","Tissue RNA - liver [nTPM]":"15.5","Tissue RNA - lung [nTPM]":"12.0","Tissue RNA - lymph node [nTPM]":"9.0","Tissue RNA - medulla oblongata [nTPM]":"8.3","Tissue RNA - midbrain [nTPM]":"9.5","Tissue RNA - ovary [nTPM]":"14.1","Tissue RNA - pancreas [nTPM]":"10.6","Tissue RNA - parathyroid gland [nTPM]":"16.3","Tissue RNA - pituitary gland [nTPM]":"10.0","Tissue RNA - placenta [nTPM]":"24.0","Tissue RNA - pons [nTPM]":"11.3","Tissue RNA - prostate [nTPM]":"13.2","Tissue RNA - rectum [nTPM]":"14.1","Tissue RNA - retina [nTPM]":"51.9","Tissue RNA - salivary gland [nTPM]":"10.7","Tissue RNA - seminal vesicle [nTPM]":"11.0","Tissue RNA - skeletal muscle [nTPM]":"19.9","Tissue RNA - skin 1 [nTPM]":"11.6","Tissue RNA - small intestine [nTPM]":"9.1","Tissue RNA - smooth muscle [nTPM]":"18.9","Tissue RNA - spinal cord [nTPM]":"5.1","Tissue RNA - spleen [nTPM]":"9.7","Tissue RNA - stomach 1 [nTPM]":"11.0","Tissue RNA - testis [nTPM]":"13.1","Tissue RNA - thalamus [nTPM]":"12.4","Tissue RNA - thymus [nTPM]":"9.4","Tissue RNA - thyroid gland [nTPM]":"14.0","Tissue RNA - tongue [nTPM]":"14.3","Tissue RNA - tonsil [nTPM]":"10.5","Tissue RNA - urinary bladder [nTPM]":"11.7","Tissue RNA - vagina [nTPM]":"9.8","Tissue RNA - white matter [nTPM]":"8.8","Cell RNA - A-431 [nTPM]":"41.1","Cell RNA - A549 [nTPM]":"36.5","Cell RNA - AF22 [nTPM]":"40.3","Cell RNA - AN3-CA [nTPM]":"105.4","Cell RNA - ASC diff [nTPM]":"63.6","Cell RNA - ASC TERT1 [nTPM]":"49.3","Cell RNA - BEWO [nTPM]":"78.3","Cell RNA - BJ [nTPM]":"65.1","Cell RNA - BJ hTERT+ [nTPM]":"60.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"88.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"86.8","Cell RNA - CACO-2 [nTPM]":"38.4","Cell RNA - CAPAN-2 [nTPM]":"92.5","Cell RNA - Daudi [nTPM]":"36.5","Cell RNA - EFO-21 [nTPM]":"84.1","Cell RNA - fHDF\/TERT166 [nTPM]":"100.6","Cell RNA - GAMG [nTPM]":"57.1","Cell RNA - HaCaT [nTPM]":"45.4","Cell RNA - HAP1 [nTPM]":"56.7","Cell RNA - HBEC3-KT [nTPM]":"73.0","Cell RNA - HBF TERT88 [nTPM]":"102.1","Cell RNA - HDLM-2 [nTPM]":"31.0","Cell RNA - HEK 293 [nTPM]":"29.6","Cell RNA - HEL [nTPM]":"44.0","Cell RNA - HeLa [nTPM]":"46.3","Cell RNA - Hep G2 [nTPM]":"45.5","Cell RNA - HHSteC [nTPM]":"46.2","Cell RNA - HL-60 [nTPM]":"56.9","Cell RNA - HMC-1 [nTPM]":"50.7","Cell RNA - HSkMC [nTPM]":"52.7","Cell RNA - hTCEpi [nTPM]":"46.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"104.6","Cell RNA - hTERT-HME1 [nTPM]":"86.2","Cell RNA - hTERT-RPE1 [nTPM]":"82.2","Cell RNA - HUVEC TERT2 [nTPM]":"75.6","Cell RNA - JURKAT [nTPM]":"31.2","Cell RNA - K-562 [nTPM]":"55.1","Cell RNA - Karpas-707 [nTPM]":"53.7","Cell RNA - LHCN-M2 [nTPM]":"69.1","Cell RNA - MCF7 [nTPM]":"23.5","Cell RNA - MOLT-4 [nTPM]":"23.3","Cell RNA - NB-4 [nTPM]":"27.9","Cell RNA - NTERA-2 [nTPM]":"24.4","Cell RNA - OE19 [nTPM]":"47.2","Cell RNA - PC-3 [nTPM]":"33.9","Cell RNA - REH [nTPM]":"34.4","Cell RNA - RH-30 [nTPM]":"49.7","Cell RNA - RPMI-8226 [nTPM]":"64.2","Cell RNA - RPTEC TERT1 [nTPM]":"35.8","Cell RNA - RT4 [nTPM]":"18.8","Cell RNA - SCLC-21H [nTPM]":"49.6","Cell RNA - SH-SY5Y [nTPM]":"33.9","Cell RNA - SiHa [nTPM]":"71.5","Cell RNA - SK-BR-3 [nTPM]":"37.0","Cell RNA - SK-MEL-30 [nTPM]":"54.6","Cell RNA - SuSa [nTPM]":"47.2","Cell RNA - T-47d [nTPM]":"40.5","Cell RNA - THP-1 [nTPM]":"35.3","Cell RNA - TIME [nTPM]":"67.3","Cell RNA - U-138 MG [nTPM]":"79.5","Cell RNA - U-2 OS [nTPM]":"51.7","Cell RNA - U-2197 [nTPM]":"61.2","Cell RNA - U-251 MG [nTPM]":"75.2","Cell RNA - U-266\/70 [nTPM]":"29.7","Cell RNA - U-266\/84 [nTPM]":"67.0","Cell RNA - U-698 [nTPM]":"46.3","Cell RNA - U-87 MG [nTPM]":"75.4","Cell RNA - U-937 [nTPM]":"73.5","Cell RNA - WM-115 [nTPM]":"108.4","Blood RNA - basophil [nTPM]":"5.2","Blood RNA - classical monocyte [nTPM]":"12.7","Blood RNA - eosinophil [nTPM]":"3.1","Blood RNA - gdT-cell [nTPM]":"8.1","Blood RNA - intermediate monocyte [nTPM]":"9.6","Blood RNA - MAIT T-cell [nTPM]":"9.0","Blood RNA - memory B-cell [nTPM]":"6.2","Blood RNA - memory CD4 T-cell [nTPM]":"8.1","Blood RNA - memory CD8 T-cell [nTPM]":"9.2","Blood RNA - myeloid DC [nTPM]":"12.6","Blood RNA - naive B-cell [nTPM]":"7.0","Blood RNA - naive CD4 T-cell [nTPM]":"8.0","Blood RNA - naive CD8 T-cell [nTPM]":"8.0","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"21.7","Blood RNA - non-classical monocyte [nTPM]":"12.8","Blood RNA - plasmacytoid DC [nTPM]":"6.1","Blood RNA - T-reg [nTPM]":"6.2","Blood RNA - total PBMC [nTPM]":"9.1","Brain RNA - amygdala [nTPM]":"10.1","Brain RNA - basal ganglia [nTPM]":"11.6","Brain RNA - cerebellum [nTPM]":"11.7","Brain RNA - cerebral cortex [nTPM]":"14.0","Brain RNA - hippocampal formation [nTPM]":"11.8","Brain RNA - hypothalamus [nTPM]":"16.0","Brain RNA - medulla oblongata [nTPM]":"8.3","Brain RNA - midbrain [nTPM]":"9.5","Brain RNA - pons [nTPM]":"11.3","Brain RNA - spinal cord [nTPM]":"5.1","Brain RNA - thalamus [nTPM]":"12.4","Brain RNA - white matter [nTPM]":"8.8","Single Cell Type RNA - Adipocytes [nTPM]":"13.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.6","Single Cell Type RNA - Astrocytes [nTPM]":"8.1","Single Cell Type RNA - B-cells [nTPM]":"12.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"20.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"10.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"40.4","Single Cell Type RNA - dendritic cells [nTPM]":"9.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"14.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.0","Single Cell Type RNA - Endothelial cells [nTPM]":"16.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.7","Single Cell Type RNA - Erythroid cells [nTPM]":"6.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"41.0","Single Cell Type RNA - Fibroblasts [nTPM]":"19.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.0","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"23.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.3","Single Cell Type RNA - Hepatocytes [nTPM]":"25.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.4","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.4","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"12.3","Single Cell Type RNA - Langerhans cells [nTPM]":"7.3","Single Cell Type RNA - Late spermatids [nTPM]":"2.6","Single Cell Type RNA - Leydig cells [nTPM]":"14.9","Single Cell Type RNA - Macrophages [nTPM]":"11.5","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"12.0","Single Cell Type RNA - Muller glia cells [nTPM]":"19.0","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.6","Single Cell Type RNA - Paneth cells [nTPM]":"9.4","Single Cell Type RNA - Peritubular cells [nTPM]":"14.3","Single Cell Type RNA - Plasma cells [nTPM]":"14.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"63.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.5","Single Cell Type RNA - Spermatocytes [nTPM]":"12.9","Single Cell Type RNA - Spermatogonia [nTPM]":"19.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"36.0","Single Cell Type RNA - T-cells [nTPM]":"8.9","Single Cell Type RNA - Theca cells [nTPM]":"18.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.7","Single Cell Type RNA - Urothelial cells [nTPM]":"6.7"},{"Gene":"ENO3","Gene synonym":[],"Ensembl":"ENSG00000108515","Gene description":"Enolase 3","Uniprot":["P13929"],"Chromosome":"17","Position":"4948092-4957131","Protein class":["Candidate cardiovascular disease genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Glycolysis"],"Molecular function":["Lyase"],"Disease involvement":["Disease variant","Glycogen storage disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"26","RNA tissue specific nTPM":{"skeletal muscle":"14758.3","tongue":"10771.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cardiomyocytes":"582.2","Skeletal myocytes":"248.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"263.8","HeLa":"120.0","HMC-1":"115.1","RH-30":"170.2","RPMI-8226":"96.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000793","HPA068284","HPA068721"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"86000000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 37: Myocytes - Muscle contraction","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA000793":"AB_1078742","HPA068284":null,"HPA068721":"AB_2732119"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.33e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.8","Tissue RNA - adrenal gland [nTPM]":"5.5","Tissue RNA - amygdala [nTPM]":"3.8","Tissue RNA - appendix [nTPM]":"15.6","Tissue RNA - basal ganglia [nTPM]":"3.9","Tissue RNA - bone marrow [nTPM]":"20.4","Tissue RNA - breast [nTPM]":"8.0","Tissue RNA - cerebellum [nTPM]":"7.1","Tissue RNA - cerebral cortex [nTPM]":"4.3","Tissue RNA - cervix [nTPM]":"6.6","Tissue RNA - choroid plexus [nTPM]":"5.0","Tissue RNA - colon [nTPM]":"8.0","Tissue RNA - duodenum [nTPM]":"20.1","Tissue RNA - endometrium 1 [nTPM]":"7.2","Tissue RNA - epididymis [nTPM]":"7.1","Tissue RNA - esophagus [nTPM]":"173.8","Tissue RNA - fallopian tube [nTPM]":"7.4","Tissue RNA - gallbladder [nTPM]":"2.6","Tissue RNA - heart muscle [nTPM]":"499.8","Tissue RNA - hippocampal formation [nTPM]":"3.5","Tissue RNA - hypothalamus [nTPM]":"3.7","Tissue RNA - kidney [nTPM]":"10.3","Tissue RNA - liver [nTPM]":"108.0","Tissue RNA - lung [nTPM]":"8.6","Tissue RNA - lymph node [nTPM]":"13.0","Tissue RNA - medulla oblongata [nTPM]":"4.3","Tissue RNA - midbrain [nTPM]":"5.0","Tissue RNA - ovary [nTPM]":"6.0","Tissue RNA - pancreas [nTPM]":"5.5","Tissue RNA - parathyroid gland [nTPM]":"4.0","Tissue RNA - pituitary gland [nTPM]":"7.9","Tissue RNA - placenta [nTPM]":"6.3","Tissue RNA - pons [nTPM]":"4.6","Tissue RNA - prostate [nTPM]":"47.3","Tissue RNA - rectum [nTPM]":"3.0","Tissue RNA - retina [nTPM]":"5.0","Tissue RNA - salivary gland [nTPM]":"116.8","Tissue RNA - seminal vesicle [nTPM]":"3.1","Tissue RNA - skeletal muscle [nTPM]":"14758.3","Tissue RNA - skin 1 [nTPM]":"8.3","Tissue RNA - small intestine [nTPM]":"15.6","Tissue RNA - smooth muscle [nTPM]":"2.8","Tissue RNA - spinal cord [nTPM]":"4.1","Tissue RNA - spleen [nTPM]":"16.9","Tissue RNA - stomach 1 [nTPM]":"10.1","Tissue RNA - testis [nTPM]":"9.3","Tissue RNA - thalamus [nTPM]":"4.3","Tissue RNA - thymus [nTPM]":"5.8","Tissue RNA - thyroid gland [nTPM]":"10.3","Tissue RNA - tongue [nTPM]":"10771.0","Tissue RNA - tonsil [nTPM]":"4.9","Tissue RNA - urinary bladder [nTPM]":"5.6","Tissue RNA - vagina [nTPM]":"5.0","Tissue RNA - white matter [nTPM]":"4.9","Cell RNA - A-431 [nTPM]":"12.0","Cell RNA - A549 [nTPM]":"25.5","Cell RNA - AF22 [nTPM]":"11.3","Cell RNA - AN3-CA [nTPM]":"10.7","Cell RNA - ASC diff [nTPM]":"9.1","Cell RNA - ASC TERT1 [nTPM]":"2.2","Cell RNA - BEWO [nTPM]":"27.6","Cell RNA - BJ [nTPM]":"21.0","Cell RNA - BJ hTERT+ [nTPM]":"2.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.3","Cell RNA - CACO-2 [nTPM]":"12.8","Cell RNA - CAPAN-2 [nTPM]":"8.1","Cell RNA - Daudi [nTPM]":"21.9","Cell RNA - EFO-21 [nTPM]":"25.8","Cell RNA - fHDF\/TERT166 [nTPM]":"1.9","Cell RNA - GAMG [nTPM]":"3.5","Cell RNA - HaCaT [nTPM]":"15.4","Cell RNA - HAP1 [nTPM]":"3.8","Cell RNA - HBEC3-KT [nTPM]":"1.9","Cell RNA - HBF TERT88 [nTPM]":"1.0","Cell RNA - HDLM-2 [nTPM]":"263.8","Cell RNA - HEK 293 [nTPM]":"24.3","Cell RNA - HEL [nTPM]":"21.9","Cell RNA - HeLa [nTPM]":"120.0","Cell RNA - Hep G2 [nTPM]":"18.9","Cell RNA - HHSteC [nTPM]":"3.7","Cell RNA - HL-60 [nTPM]":"6.8","Cell RNA - HMC-1 [nTPM]":"115.1","Cell RNA - HSkMC [nTPM]":"14.4","Cell RNA - hTCEpi [nTPM]":"3.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.1","Cell RNA - hTERT-HME1 [nTPM]":"4.1","Cell RNA - hTERT-RPE1 [nTPM]":"9.8","Cell RNA - HUVEC TERT2 [nTPM]":"1.4","Cell RNA - JURKAT [nTPM]":"24.8","Cell RNA - K-562 [nTPM]":"10.2","Cell RNA - Karpas-707 [nTPM]":"39.0","Cell RNA - LHCN-M2 [nTPM]":"4.9","Cell RNA - MCF7 [nTPM]":"6.6","Cell RNA - MOLT-4 [nTPM]":"7.9","Cell RNA - NB-4 [nTPM]":"26.5","Cell RNA - NTERA-2 [nTPM]":"14.8","Cell RNA - OE19 [nTPM]":"3.3","Cell RNA - PC-3 [nTPM]":"10.6","Cell RNA - REH [nTPM]":"34.6","Cell RNA - RH-30 [nTPM]":"170.2","Cell RNA - RPMI-8226 [nTPM]":"96.9","Cell RNA - RPTEC TERT1 [nTPM]":"3.1","Cell RNA - RT4 [nTPM]":"7.9","Cell RNA - SCLC-21H [nTPM]":"7.1","Cell RNA - SH-SY5Y [nTPM]":"27.1","Cell RNA - SiHa [nTPM]":"13.6","Cell RNA - SK-BR-3 [nTPM]":"11.4","Cell RNA - SK-MEL-30 [nTPM]":"14.7","Cell RNA - SuSa [nTPM]":"7.6","Cell RNA - T-47d [nTPM]":"10.2","Cell RNA - THP-1 [nTPM]":"7.0","Cell RNA - TIME [nTPM]":"6.5","Cell RNA - U-138 MG [nTPM]":"12.1","Cell RNA - U-2 OS [nTPM]":"21.3","Cell RNA - U-2197 [nTPM]":"5.4","Cell RNA - U-251 MG [nTPM]":"16.0","Cell RNA - U-266\/70 [nTPM]":"27.6","Cell RNA - U-266\/84 [nTPM]":"16.8","Cell RNA - U-698 [nTPM]":"18.2","Cell RNA - U-87 MG [nTPM]":"6.7","Cell RNA - U-937 [nTPM]":"20.8","Cell RNA - WM-115 [nTPM]":"12.2","Blood RNA - basophil [nTPM]":"31.4","Blood RNA - classical monocyte [nTPM]":"28.5","Blood RNA - eosinophil [nTPM]":"50.4","Blood RNA - gdT-cell [nTPM]":"36.8","Blood RNA - intermediate monocyte [nTPM]":"41.5","Blood RNA - MAIT T-cell [nTPM]":"24.8","Blood RNA - memory B-cell [nTPM]":"24.5","Blood RNA - memory CD4 T-cell [nTPM]":"30.8","Blood RNA - memory CD8 T-cell [nTPM]":"34.4","Blood RNA - myeloid DC [nTPM]":"37.6","Blood RNA - naive B-cell [nTPM]":"20.1","Blood RNA - naive CD4 T-cell [nTPM]":"20.0","Blood RNA - naive CD8 T-cell [nTPM]":"32.2","Blood RNA - neutrophil [nTPM]":"34.4","Blood RNA - NK-cell [nTPM]":"34.9","Blood RNA - non-classical monocyte [nTPM]":"47.6","Blood RNA - plasmacytoid DC [nTPM]":"29.9","Blood RNA - T-reg [nTPM]":"43.2","Blood RNA - total PBMC [nTPM]":"83.6","Brain RNA - amygdala [nTPM]":"3.8","Brain RNA - basal ganglia [nTPM]":"3.9","Brain RNA - cerebellum [nTPM]":"7.1","Brain RNA - cerebral cortex [nTPM]":"4.3","Brain RNA - hippocampal formation [nTPM]":"3.5","Brain RNA - hypothalamus [nTPM]":"3.7","Brain RNA - medulla oblongata [nTPM]":"4.3","Brain RNA - midbrain [nTPM]":"5.0","Brain RNA - pons [nTPM]":"4.6","Brain RNA - spinal cord [nTPM]":"4.1","Brain RNA - thalamus [nTPM]":"4.3","Brain RNA - white matter [nTPM]":"4.9","Single Cell Type RNA - Adipocytes [nTPM]":"1.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.8","Single Cell Type RNA - Astrocytes [nTPM]":"2.3","Single Cell Type RNA - B-cells [nTPM]":"2.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"6.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"582.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.4","Single Cell Type RNA - dendritic cells [nTPM]":"3.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.5","Single Cell Type RNA - Early spermatids [nTPM]":"1.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.6","Single Cell Type RNA - Endothelial cells [nTPM]":"7.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.8","Single Cell Type RNA - Fibroblasts [nTPM]":"17.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.2","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"2.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"56.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.5","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.2","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.5","Single Cell Type RNA - Langerhans cells [nTPM]":"6.7","Single Cell Type RNA - Late spermatids [nTPM]":"3.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"4.3","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"78.3","Single Cell Type RNA - Muller glia cells [nTPM]":"1.9","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.8","Single Cell Type RNA - Paneth cells [nTPM]":"1.9","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"2.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"248.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"55.8","Single Cell Type RNA - Spermatocytes [nTPM]":"7.9","Single Cell Type RNA - Spermatogonia [nTPM]":"7.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.3","Single Cell Type RNA - T-cells [nTPM]":"4.5","Single Cell Type RNA - Theca cells [nTPM]":"1.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"ENPP1","Gene synonym":["M6S1","NPPS","PC-1","PCA1","PDNP1"],"Ensembl":"ENSG00000197594","Gene description":"Ectonucleotide pyrophosphatase\/phosphodiesterase 1","Uniprot":["P22413"],"Chromosome":"6","Position":"131808016-131895155","Protein class":["CD markers","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Biomineralization"],"Molecular function":["Hydrolase"],"Disease involvement":["Diabetes mellitus","Disease variant","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"44.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"80.2","Fibroblasts":"56.9","Hepatocytes":"111.6","Peritubular cells":"70.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"1.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"34.1","LHCN-M2":"21.1","U-138 MG":"27.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB032904","HPA062066"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4400000","Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB032904":"AB_2099635","HPA062066":"AB_2684674"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-3"},"Tissue RNA - adipose tissue [nTPM]":"8.4","Tissue RNA - adrenal gland [nTPM]":"3.1","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"1.4","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"7.1","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"7.1","Tissue RNA - choroid plexus [nTPM]":"0.4","Tissue RNA - colon [nTPM]":"2.3","Tissue RNA - duodenum [nTPM]":"1.8","Tissue RNA - endometrium 1 [nTPM]":"22.1","Tissue RNA - epididymis [nTPM]":"7.4","Tissue RNA - esophagus [nTPM]":"2.3","Tissue RNA - fallopian tube [nTPM]":"6.9","Tissue RNA - gallbladder [nTPM]":"1.2","Tissue RNA - heart muscle [nTPM]":"1.6","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"0.7","Tissue RNA - kidney [nTPM]":"4.2","Tissue RNA - liver [nTPM]":"31.9","Tissue RNA - lung [nTPM]":"0.8","Tissue RNA - lymph node [nTPM]":"1.4","Tissue RNA - medulla oblongata [nTPM]":"1.2","Tissue RNA - midbrain [nTPM]":"1.4","Tissue RNA - ovary [nTPM]":"8.3","Tissue RNA - pancreas [nTPM]":"28.5","Tissue RNA - parathyroid gland [nTPM]":"27.8","Tissue RNA - pituitary gland [nTPM]":"10.9","Tissue RNA - placenta [nTPM]":"44.0","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"3.4","Tissue RNA - rectum [nTPM]":"2.0","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"4.2","Tissue RNA - seminal vesicle [nTPM]":"5.8","Tissue RNA - skeletal muscle [nTPM]":"2.7","Tissue RNA - skin 1 [nTPM]":"1.7","Tissue RNA - small intestine [nTPM]":"1.3","Tissue RNA - smooth muscle [nTPM]":"10.2","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"1.9","Tissue RNA - stomach 1 [nTPM]":"1.7","Tissue RNA - testis [nTPM]":"1.6","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"2.2","Tissue RNA - thyroid gland [nTPM]":"20.1","Tissue RNA - tongue [nTPM]":"3.2","Tissue RNA - tonsil [nTPM]":"0.8","Tissue RNA - urinary bladder [nTPM]":"2.7","Tissue RNA - vagina [nTPM]":"4.9","Tissue RNA - white matter [nTPM]":"0.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"1.3","Cell RNA - AF22 [nTPM]":"1.2","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"34.1","Cell RNA - ASC TERT1 [nTPM]":"5.3","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"9.2","Cell RNA - BJ hTERT+ [nTPM]":"9.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.5","Cell RNA - CACO-2 [nTPM]":"4.1","Cell RNA - CAPAN-2 [nTPM]":"1.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.8","Cell RNA - fHDF\/TERT166 [nTPM]":"5.9","Cell RNA - GAMG [nTPM]":"7.2","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"1.3","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"14.8","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"1.8","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"1.1","Cell RNA - Hep G2 [nTPM]":"12.0","Cell RNA - HHSteC [nTPM]":"1.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"4.2","Cell RNA - HSkMC [nTPM]":"8.8","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.6","Cell RNA - hTERT-HME1 [nTPM]":"0.4","Cell RNA - hTERT-RPE1 [nTPM]":"4.1","Cell RNA - HUVEC TERT2 [nTPM]":"4.3","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"1.8","Cell RNA - LHCN-M2 [nTPM]":"21.1","Cell RNA - MCF7 [nTPM]":"2.6","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"7.9","Cell RNA - OE19 [nTPM]":"1.6","Cell RNA - PC-3 [nTPM]":"1.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"10.2","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"3.4","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"1.3","Cell RNA - SK-MEL-30 [nTPM]":"4.2","Cell RNA - SuSa [nTPM]":"5.7","Cell RNA - T-47d [nTPM]":"3.9","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"2.9","Cell RNA - U-138 MG [nTPM]":"27.6","Cell RNA - U-2 OS [nTPM]":"1.0","Cell RNA - U-2197 [nTPM]":"1.9","Cell RNA - U-251 MG [nTPM]":"9.1","Cell RNA - U-266\/70 [nTPM]":"3.4","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"12.6","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"3.5","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"1.6","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"0.7","Brain RNA - medulla oblongata [nTPM]":"1.2","Brain RNA - midbrain [nTPM]":"1.4","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"0.8","Single Cell Type RNA - Adipocytes [nTPM]":"2.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"1.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"4.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"28.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"19.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"4.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"80.2","Single Cell Type RNA - Endothelial cells [nTPM]":"4.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"8.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.1","Single Cell Type RNA - Fibroblasts [nTPM]":"56.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"9.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"111.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.6","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.9","Single Cell Type RNA - Langerhans cells [nTPM]":"5.9","Single Cell Type RNA - Late spermatids [nTPM]":"6.7","Single Cell Type RNA - Leydig cells [nTPM]":"25.1","Single Cell Type RNA - Macrophages [nTPM]":"3.9","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"3.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.2","Single Cell Type RNA - Paneth cells [nTPM]":"3.9","Single Cell Type RNA - Peritubular cells [nTPM]":"70.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"25.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.8","Single Cell Type RNA - Spermatocytes [nTPM]":"4.1","Single Cell Type RNA - Spermatogonia [nTPM]":"2.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.2","Single Cell Type RNA - T-cells [nTPM]":"2.6","Single Cell Type RNA - Theca cells [nTPM]":"1.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.5","Single Cell Type RNA - Urothelial cells [nTPM]":"1.7"},{"Gene":"ENTPD1","Gene synonym":["ATPDase","CD39","NTPDase-1","SPG64"],"Ensembl":"ENSG00000138185","Gene description":"Ectonucleoside triphosphate diphosphohydrolase 1","Uniprot":["P49961"],"Chromosome":"10","Position":"95711779-95877266","Protein class":["CD markers","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"74.1","Kupffer cells":"110.4","Langerhans cells":"161.3","Microglial cells":"217.4","monocytes":"112.2","Plasma cells":"80.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"17.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"102.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"31.9","granulocytes":"102.2","monocytes":"41.0"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"HDLM-2":"147.5","Karpas-707":"135.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002494","HPA014067","CAB079986"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"19000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"CAB002494":"AB_563557","CAB079986":null,"HPA014067":"AB_1848178"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.68e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.33e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.89e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.8","Tissue RNA - adrenal gland [nTPM]":"8.3","Tissue RNA - amygdala [nTPM]":"5.9","Tissue RNA - appendix [nTPM]":"24.7","Tissue RNA - basal ganglia [nTPM]":"5.5","Tissue RNA - bone marrow [nTPM]":"27.5","Tissue RNA - breast [nTPM]":"10.8","Tissue RNA - cerebellum [nTPM]":"5.0","Tissue RNA - cerebral cortex [nTPM]":"6.3","Tissue RNA - cervix [nTPM]":"17.5","Tissue RNA - choroid plexus [nTPM]":"5.0","Tissue RNA - colon [nTPM]":"14.3","Tissue RNA - duodenum [nTPM]":"9.3","Tissue RNA - endometrium 1 [nTPM]":"28.0","Tissue RNA - epididymis [nTPM]":"19.3","Tissue RNA - esophagus [nTPM]":"19.2","Tissue RNA - fallopian tube [nTPM]":"14.0","Tissue RNA - gallbladder [nTPM]":"27.7","Tissue RNA - heart muscle [nTPM]":"8.5","Tissue RNA - hippocampal formation [nTPM]":"5.3","Tissue RNA - hypothalamus [nTPM]":"6.3","Tissue RNA - kidney [nTPM]":"7.6","Tissue RNA - liver [nTPM]":"5.4","Tissue RNA - lung [nTPM]":"16.1","Tissue RNA - lymph node [nTPM]":"20.2","Tissue RNA - medulla oblongata [nTPM]":"7.1","Tissue RNA - midbrain [nTPM]":"6.5","Tissue RNA - ovary [nTPM]":"5.5","Tissue RNA - pancreas [nTPM]":"2.8","Tissue RNA - parathyroid gland [nTPM]":"3.4","Tissue RNA - pituitary gland [nTPM]":"3.9","Tissue RNA - placenta [nTPM]":"11.4","Tissue RNA - pons [nTPM]":"7.7","Tissue RNA - prostate [nTPM]":"11.2","Tissue RNA - rectum [nTPM]":"12.8","Tissue RNA - retina [nTPM]":"6.8","Tissue RNA - salivary gland [nTPM]":"6.0","Tissue RNA - seminal vesicle [nTPM]":"18.1","Tissue RNA - skeletal muscle [nTPM]":"4.0","Tissue RNA - skin 1 [nTPM]":"6.3","Tissue RNA - small intestine [nTPM]":"11.7","Tissue RNA - smooth muscle [nTPM]":"49.7","Tissue RNA - spinal cord [nTPM]":"6.2","Tissue RNA - spleen [nTPM]":"21.5","Tissue RNA - stomach 1 [nTPM]":"7.3","Tissue RNA - testis [nTPM]":"4.5","Tissue RNA - thalamus [nTPM]":"7.5","Tissue RNA - thymus [nTPM]":"6.8","Tissue RNA - thyroid gland [nTPM]":"20.0","Tissue RNA - tongue [nTPM]":"8.7","Tissue RNA - tonsil [nTPM]":"25.6","Tissue RNA - urinary bladder [nTPM]":"30.6","Tissue RNA - vagina [nTPM]":"11.0","Tissue RNA - white matter [nTPM]":"6.3","Cell RNA - A-431 [nTPM]":"1.4","Cell RNA - A549 [nTPM]":"2.7","Cell RNA - AF22 [nTPM]":"5.4","Cell RNA - AN3-CA [nTPM]":"7.1","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"5.0","Cell RNA - BJ [nTPM]":"4.5","Cell RNA - BJ hTERT+ [nTPM]":"1.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"4.0","Cell RNA - CAPAN-2 [nTPM]":"1.6","Cell RNA - Daudi [nTPM]":"8.2","Cell RNA - EFO-21 [nTPM]":"3.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"5.3","Cell RNA - HaCaT [nTPM]":"2.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"147.5","Cell RNA - HEK 293 [nTPM]":"5.2","Cell RNA - HEL [nTPM]":"7.2","Cell RNA - HeLa [nTPM]":"4.0","Cell RNA - Hep G2 [nTPM]":"4.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"12.5","Cell RNA - HMC-1 [nTPM]":"4.1","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.6","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"2.4","Cell RNA - HUVEC TERT2 [nTPM]":"18.2","Cell RNA - JURKAT [nTPM]":"2.0","Cell RNA - K-562 [nTPM]":"5.3","Cell RNA - Karpas-707 [nTPM]":"135.4","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"4.4","Cell RNA - MOLT-4 [nTPM]":"4.7","Cell RNA - NB-4 [nTPM]":"5.8","Cell RNA - NTERA-2 [nTPM]":"5.9","Cell RNA - OE19 [nTPM]":"3.6","Cell RNA - PC-3 [nTPM]":"2.8","Cell RNA - REH [nTPM]":"15.3","Cell RNA - RH-30 [nTPM]":"2.4","Cell RNA - RPMI-8226 [nTPM]":"4.4","Cell RNA - RPTEC TERT1 [nTPM]":"1.7","Cell RNA - RT4 [nTPM]":"2.2","Cell RNA - SCLC-21H [nTPM]":"5.1","Cell RNA - SH-SY5Y [nTPM]":"6.2","Cell RNA - SiHa [nTPM]":"3.6","Cell RNA - SK-BR-3 [nTPM]":"3.7","Cell RNA - SK-MEL-30 [nTPM]":"3.9","Cell RNA - SuSa [nTPM]":"3.6","Cell RNA - T-47d [nTPM]":"5.5","Cell RNA - THP-1 [nTPM]":"5.9","Cell RNA - TIME [nTPM]":"3.9","Cell RNA - U-138 MG [nTPM]":"3.9","Cell RNA - U-2 OS [nTPM]":"2.8","Cell RNA - U-2197 [nTPM]":"3.8","Cell RNA - U-251 MG [nTPM]":"5.3","Cell RNA - U-266\/70 [nTPM]":"21.6","Cell RNA - U-266\/84 [nTPM]":"7.2","Cell RNA - U-698 [nTPM]":"0.6","Cell RNA - U-87 MG [nTPM]":"4.3","Cell RNA - U-937 [nTPM]":"13.9","Cell RNA - WM-115 [nTPM]":"2.7","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"41.0","Blood RNA - eosinophil [nTPM]":"102.2","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"27.2","Blood RNA - MAIT T-cell [nTPM]":"1.1","Blood RNA - memory B-cell [nTPM]":"13.7","Blood RNA - memory CD4 T-cell [nTPM]":"1.6","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"31.9","Blood RNA - naive B-cell [nTPM]":"11.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"49.4","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"6.7","Blood RNA - plasmacytoid DC [nTPM]":"2.1","Blood RNA - T-reg [nTPM]":"13.1","Blood RNA - total PBMC [nTPM]":"15.5","Brain RNA - amygdala [nTPM]":"5.9","Brain RNA - basal ganglia [nTPM]":"5.5","Brain RNA - cerebellum [nTPM]":"5.0","Brain RNA - cerebral cortex [nTPM]":"6.3","Brain RNA - hippocampal formation [nTPM]":"5.3","Brain RNA - hypothalamus [nTPM]":"6.3","Brain RNA - medulla oblongata [nTPM]":"7.1","Brain RNA - midbrain [nTPM]":"6.5","Brain RNA - pons [nTPM]":"7.7","Brain RNA - spinal cord [nTPM]":"6.2","Brain RNA - thalamus [nTPM]":"7.5","Brain RNA - white matter [nTPM]":"6.3","Single Cell Type RNA - Adipocytes [nTPM]":"19.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"74.1","Single Cell Type RNA - B-cells [nTPM]":"40.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.6","Single Cell Type RNA - dendritic cells [nTPM]":"3.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"10.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.6","Single Cell Type RNA - Endothelial cells [nTPM]":"60.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"4.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.9","Single Cell Type RNA - Fibroblasts [nTPM]":"15.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.6","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"31.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"26.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"110.4","Single Cell Type RNA - Langerhans cells [nTPM]":"161.3","Single Cell Type RNA - Late spermatids [nTPM]":"7.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"62.1","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"217.4","Single Cell Type RNA - monocytes [nTPM]":"112.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"80.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.7","Single Cell Type RNA - Spermatocytes [nTPM]":"10.1","Single Cell Type RNA - Spermatogonia [nTPM]":"4.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.7","Single Cell Type RNA - T-cells [nTPM]":"26.9","Single Cell Type RNA - Theca cells [nTPM]":"15.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.5"},{"Gene":"EOGT","Gene synonym":["AER61","C3orf64","FLJ33770"],"Ensembl":"ENSG00000163378","Gene description":"EGF domain specific O-linked N-acetylglucosamine transferase","Uniprot":["Q5NDL2"],"Chromosome":"3","Position":"68975217-69013684","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Peritubular cells":"40.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HUVEC TERT2":"86.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019460"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm","Nuclear membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA019460":"AB_1844628"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.97e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Tissue RNA - adipose tissue [nTPM]":"19.4","Tissue RNA - adrenal gland [nTPM]":"9.1","Tissue RNA - amygdala [nTPM]":"7.2","Tissue RNA - appendix [nTPM]":"12.8","Tissue RNA - basal ganglia [nTPM]":"7.2","Tissue RNA - bone marrow [nTPM]":"5.9","Tissue RNA - breast [nTPM]":"19.5","Tissue RNA - cerebellum [nTPM]":"6.7","Tissue RNA - cerebral cortex [nTPM]":"10.9","Tissue RNA - cervix [nTPM]":"14.0","Tissue RNA - choroid plexus [nTPM]":"22.4","Tissue RNA - colon [nTPM]":"25.8","Tissue RNA - duodenum [nTPM]":"7.4","Tissue RNA - endometrium 1 [nTPM]":"29.9","Tissue RNA - epididymis [nTPM]":"9.8","Tissue RNA - esophagus [nTPM]":"17.5","Tissue RNA - fallopian tube [nTPM]":"18.5","Tissue RNA - gallbladder [nTPM]":"17.8","Tissue RNA - heart muscle [nTPM]":"28.5","Tissue RNA - hippocampal formation [nTPM]":"7.1","Tissue RNA - hypothalamus [nTPM]":"7.0","Tissue RNA - kidney [nTPM]":"10.2","Tissue RNA - liver [nTPM]":"5.7","Tissue RNA - lung [nTPM]":"28.7","Tissue RNA - lymph node [nTPM]":"8.2","Tissue RNA - medulla oblongata [nTPM]":"7.7","Tissue RNA - midbrain [nTPM]":"7.6","Tissue RNA - ovary [nTPM]":"11.6","Tissue RNA - pancreas [nTPM]":"12.6","Tissue RNA - parathyroid gland [nTPM]":"5.0","Tissue RNA - pituitary gland [nTPM]":"9.3","Tissue RNA - placenta [nTPM]":"22.3","Tissue RNA - pons [nTPM]":"8.0","Tissue RNA - prostate [nTPM]":"27.9","Tissue RNA - rectum [nTPM]":"8.6","Tissue RNA - retina [nTPM]":"8.8","Tissue RNA - salivary gland [nTPM]":"16.4","Tissue RNA - seminal vesicle [nTPM]":"33.7","Tissue RNA - skeletal muscle [nTPM]":"20.0","Tissue RNA - skin 1 [nTPM]":"9.7","Tissue RNA - small intestine [nTPM]":"11.4","Tissue RNA - smooth muscle [nTPM]":"25.4","Tissue RNA - spinal cord [nTPM]":"7.8","Tissue RNA - spleen [nTPM]":"10.0","Tissue RNA - stomach 1 [nTPM]":"15.5","Tissue RNA - testis [nTPM]":"8.9","Tissue RNA - thalamus [nTPM]":"7.8","Tissue RNA - thymus [nTPM]":"11.1","Tissue RNA - thyroid gland [nTPM]":"7.9","Tissue RNA - tongue [nTPM]":"15.2","Tissue RNA - tonsil [nTPM]":"8.8","Tissue RNA - urinary bladder [nTPM]":"24.7","Tissue RNA - vagina [nTPM]":"13.7","Tissue RNA - white matter [nTPM]":"7.5","Cell RNA - A-431 [nTPM]":"19.0","Cell RNA - A549 [nTPM]":"7.1","Cell RNA - AF22 [nTPM]":"12.5","Cell RNA - AN3-CA [nTPM]":"14.4","Cell RNA - ASC diff [nTPM]":"16.6","Cell RNA - ASC TERT1 [nTPM]":"32.2","Cell RNA - BEWO [nTPM]":"8.6","Cell RNA - BJ [nTPM]":"25.4","Cell RNA - BJ hTERT+ [nTPM]":"31.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.0","Cell RNA - CACO-2 [nTPM]":"9.1","Cell RNA - CAPAN-2 [nTPM]":"10.2","Cell RNA - Daudi [nTPM]":"1.1","Cell RNA - EFO-21 [nTPM]":"3.8","Cell RNA - fHDF\/TERT166 [nTPM]":"28.1","Cell RNA - GAMG [nTPM]":"13.6","Cell RNA - HaCaT [nTPM]":"6.0","Cell RNA - HAP1 [nTPM]":"8.3","Cell RNA - HBEC3-KT [nTPM]":"32.3","Cell RNA - HBF TERT88 [nTPM]":"19.9","Cell RNA - HDLM-2 [nTPM]":"62.3","Cell RNA - HEK 293 [nTPM]":"5.6","Cell RNA - HEL [nTPM]":"20.2","Cell RNA - HeLa [nTPM]":"15.5","Cell RNA - Hep G2 [nTPM]":"13.5","Cell RNA - HHSteC [nTPM]":"18.7","Cell RNA - HL-60 [nTPM]":"11.5","Cell RNA - HMC-1 [nTPM]":"8.2","Cell RNA - HSkMC [nTPM]":"26.8","Cell RNA - hTCEpi [nTPM]":"29.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.6","Cell RNA - hTERT-HME1 [nTPM]":"25.1","Cell RNA - hTERT-RPE1 [nTPM]":"19.4","Cell RNA - HUVEC TERT2 [nTPM]":"86.2","Cell RNA - JURKAT [nTPM]":"0.8","Cell RNA - K-562 [nTPM]":"5.9","Cell RNA - Karpas-707 [nTPM]":"11.1","Cell RNA - LHCN-M2 [nTPM]":"53.7","Cell RNA - MCF7 [nTPM]":"5.5","Cell RNA - MOLT-4 [nTPM]":"2.0","Cell RNA - NB-4 [nTPM]":"3.8","Cell RNA - NTERA-2 [nTPM]":"13.5","Cell RNA - OE19 [nTPM]":"6.2","Cell RNA - PC-3 [nTPM]":"3.5","Cell RNA - REH [nTPM]":"0.8","Cell RNA - RH-30 [nTPM]":"12.4","Cell RNA - RPMI-8226 [nTPM]":"8.2","Cell RNA - RPTEC TERT1 [nTPM]":"13.9","Cell RNA - RT4 [nTPM]":"43.4","Cell RNA - SCLC-21H [nTPM]":"1.2","Cell RNA - SH-SY5Y [nTPM]":"6.3","Cell RNA - SiHa [nTPM]":"29.1","Cell RNA - SK-BR-3 [nTPM]":"1.7","Cell RNA - SK-MEL-30 [nTPM]":"23.5","Cell RNA - SuSa [nTPM]":"12.8","Cell RNA - T-47d [nTPM]":"6.0","Cell RNA - THP-1 [nTPM]":"15.9","Cell RNA - TIME [nTPM]":"44.6","Cell RNA - U-138 MG [nTPM]":"40.6","Cell RNA - U-2 OS [nTPM]":"13.4","Cell RNA - U-2197 [nTPM]":"5.1","Cell RNA - U-251 MG [nTPM]":"24.3","Cell RNA - U-266\/70 [nTPM]":"6.0","Cell RNA - U-266\/84 [nTPM]":"20.5","Cell RNA - U-698 [nTPM]":"9.3","Cell RNA - U-87 MG [nTPM]":"16.3","Cell RNA - U-937 [nTPM]":"17.1","Cell RNA - WM-115 [nTPM]":"23.8","Blood RNA - basophil [nTPM]":"5.4","Blood RNA - classical monocyte [nTPM]":"1.5","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"2.0","Blood RNA - intermediate monocyte [nTPM]":"1.4","Blood RNA - MAIT T-cell [nTPM]":"2.3","Blood RNA - memory B-cell [nTPM]":"1.1","Blood RNA - memory CD4 T-cell [nTPM]":"3.0","Blood RNA - memory CD8 T-cell [nTPM]":"4.3","Blood RNA - myeloid DC [nTPM]":"2.4","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"2.5","Blood RNA - naive CD8 T-cell [nTPM]":"2.7","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"2.4","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"6.6","Blood RNA - total PBMC [nTPM]":"1.3","Brain RNA - amygdala [nTPM]":"7.2","Brain RNA - basal ganglia [nTPM]":"7.2","Brain RNA - cerebellum [nTPM]":"6.7","Brain RNA - cerebral cortex [nTPM]":"10.9","Brain RNA - hippocampal formation [nTPM]":"7.1","Brain RNA - hypothalamus [nTPM]":"7.0","Brain RNA - medulla oblongata [nTPM]":"7.7","Brain RNA - midbrain [nTPM]":"7.6","Brain RNA - pons [nTPM]":"8.0","Brain RNA - spinal cord [nTPM]":"7.8","Brain RNA - thalamus [nTPM]":"7.8","Brain RNA - white matter [nTPM]":"7.5","Single Cell Type RNA - Adipocytes [nTPM]":"29.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.3","Single Cell Type RNA - Astrocytes [nTPM]":"14.0","Single Cell Type RNA - B-cells [nTPM]":"3.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"16.5","Single Cell Type RNA - Bipolar cells [nTPM]":"2.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"20.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"14.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.9","Single Cell Type RNA - dendritic cells [nTPM]":"3.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"4.6","Single Cell Type RNA - Early spermatids [nTPM]":"16.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.5","Single Cell Type RNA - Endothelial cells [nTPM]":"23.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.3","Single Cell Type RNA - Fibroblasts [nTPM]":"9.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"9.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.3","Single Cell Type RNA - Hepatocytes [nTPM]":"3.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.5","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"6.8","Single Cell Type RNA - Langerhans cells [nTPM]":"9.8","Single Cell Type RNA - Late spermatids [nTPM]":"15.1","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"8.6","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"30.9","Single Cell Type RNA - monocytes [nTPM]":"6.5","Single Cell Type RNA - Muller glia cells [nTPM]":"1.4","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.4","Single Cell Type RNA - Paneth cells [nTPM]":"3.4","Single Cell Type RNA - Peritubular cells [nTPM]":"40.6","Single Cell Type RNA - Plasma cells [nTPM]":"5.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"26.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.2","Single Cell Type RNA - Spermatocytes [nTPM]":"5.5","Single Cell Type RNA - Spermatogonia [nTPM]":"2.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"7.0","Single Cell Type RNA - Theca cells [nTPM]":"6.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.4","Single Cell Type RNA - Urothelial cells [nTPM]":"8.6"},{"Gene":"EP300","Gene synonym":["KAT3B","p300"],"Ensembl":"ENSG00000100393","Gene description":"E1A binding protein p300","Uniprot":["Q09472"],"Chromosome":"22","Position":"41092592-41180077","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Biological rhythms","Cell cycle","Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000146","HPA003128","HPA004112"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB000146":"AB_2533138","HPA003128":"AB_1078745","HPA004112":"AB_1078746"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.45e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.7","Tissue RNA - adrenal gland [nTPM]":"13.7","Tissue RNA - amygdala [nTPM]":"6.8","Tissue RNA - appendix [nTPM]":"17.7","Tissue RNA - basal ganglia [nTPM]":"8.9","Tissue RNA - bone marrow [nTPM]":"65.1","Tissue RNA - breast [nTPM]":"14.2","Tissue RNA - cerebellum [nTPM]":"20.5","Tissue RNA - cerebral cortex [nTPM]":"10.8","Tissue RNA - cervix [nTPM]":"16.0","Tissue RNA - choroid plexus [nTPM]":"6.1","Tissue RNA - colon [nTPM]":"16.6","Tissue RNA - duodenum [nTPM]":"13.6","Tissue RNA - endometrium 1 [nTPM]":"17.2","Tissue RNA - epididymis [nTPM]":"13.5","Tissue RNA - esophagus [nTPM]":"16.3","Tissue RNA - fallopian tube [nTPM]":"16.4","Tissue RNA - gallbladder [nTPM]":"14.2","Tissue RNA - heart muscle [nTPM]":"11.5","Tissue RNA - hippocampal formation [nTPM]":"7.1","Tissue RNA - hypothalamus [nTPM]":"9.4","Tissue RNA - kidney [nTPM]":"13.1","Tissue RNA - liver [nTPM]":"15.5","Tissue RNA - lung [nTPM]":"14.7","Tissue RNA - lymph node [nTPM]":"17.6","Tissue RNA - medulla oblongata [nTPM]":"10.6","Tissue RNA - midbrain [nTPM]":"7.8","Tissue RNA - ovary [nTPM]":"23.9","Tissue RNA - pancreas [nTPM]":"18.0","Tissue RNA - parathyroid gland [nTPM]":"23.2","Tissue RNA - pituitary gland [nTPM]":"13.4","Tissue RNA - placenta [nTPM]":"19.3","Tissue RNA - pons [nTPM]":"7.7","Tissue RNA - prostate [nTPM]":"15.0","Tissue RNA - rectum [nTPM]":"14.5","Tissue RNA - retina [nTPM]":"17.8","Tissue RNA - salivary gland [nTPM]":"15.0","Tissue RNA - seminal vesicle [nTPM]":"15.6","Tissue RNA - skeletal muscle [nTPM]":"20.4","Tissue RNA - skin 1 [nTPM]":"18.9","Tissue RNA - small intestine [nTPM]":"16.0","Tissue RNA - smooth muscle [nTPM]":"16.4","Tissue RNA - spinal cord [nTPM]":"5.3","Tissue RNA - spleen [nTPM]":"17.0","Tissue RNA - stomach 1 [nTPM]":"14.5","Tissue RNA - testis [nTPM]":"19.6","Tissue RNA - thalamus [nTPM]":"8.6","Tissue RNA - thymus [nTPM]":"27.2","Tissue RNA - thyroid gland [nTPM]":"20.2","Tissue RNA - tongue [nTPM]":"23.4","Tissue RNA - tonsil [nTPM]":"17.9","Tissue RNA - urinary bladder [nTPM]":"15.4","Tissue RNA - vagina [nTPM]":"14.8","Tissue RNA - white matter [nTPM]":"11.2","Cell RNA - A-431 [nTPM]":"31.6","Cell RNA - A549 [nTPM]":"21.7","Cell RNA - AF22 [nTPM]":"35.4","Cell RNA - AN3-CA [nTPM]":"23.0","Cell RNA - ASC diff [nTPM]":"22.2","Cell RNA - ASC TERT1 [nTPM]":"23.3","Cell RNA - BEWO [nTPM]":"32.3","Cell RNA - BJ [nTPM]":"15.0","Cell RNA - BJ hTERT+ [nTPM]":"21.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.0","Cell RNA - CACO-2 [nTPM]":"27.8","Cell RNA - CAPAN-2 [nTPM]":"12.0","Cell RNA - Daudi [nTPM]":"32.7","Cell RNA - EFO-21 [nTPM]":"12.2","Cell RNA - fHDF\/TERT166 [nTPM]":"28.4","Cell RNA - GAMG [nTPM]":"18.7","Cell RNA - HaCaT [nTPM]":"24.1","Cell RNA - HAP1 [nTPM]":"48.1","Cell RNA - HBEC3-KT [nTPM]":"20.8","Cell RNA - HBF TERT88 [nTPM]":"23.5","Cell RNA - HDLM-2 [nTPM]":"30.5","Cell RNA - HEK 293 [nTPM]":"32.2","Cell RNA - HEL [nTPM]":"24.4","Cell RNA - HeLa [nTPM]":"25.4","Cell RNA - Hep G2 [nTPM]":"22.3","Cell RNA - HHSteC [nTPM]":"26.9","Cell RNA - HL-60 [nTPM]":"59.3","Cell RNA - HMC-1 [nTPM]":"26.5","Cell RNA - HSkMC [nTPM]":"24.8","Cell RNA - hTCEpi [nTPM]":"22.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"30.0","Cell RNA - hTERT-HME1 [nTPM]":"27.0","Cell RNA - hTERT-RPE1 [nTPM]":"19.3","Cell RNA - HUVEC TERT2 [nTPM]":"24.9","Cell RNA - JURKAT [nTPM]":"18.7","Cell RNA - K-562 [nTPM]":"26.3","Cell RNA - Karpas-707 [nTPM]":"43.9","Cell RNA - LHCN-M2 [nTPM]":"18.3","Cell RNA - MCF7 [nTPM]":"12.5","Cell RNA - MOLT-4 [nTPM]":"16.2","Cell RNA - NB-4 [nTPM]":"18.9","Cell RNA - NTERA-2 [nTPM]":"27.5","Cell RNA - OE19 [nTPM]":"38.3","Cell RNA - PC-3 [nTPM]":"15.2","Cell RNA - REH [nTPM]":"33.7","Cell RNA - RH-30 [nTPM]":"16.7","Cell RNA - RPMI-8226 [nTPM]":"21.3","Cell RNA - RPTEC TERT1 [nTPM]":"20.3","Cell RNA - RT4 [nTPM]":"40.4","Cell RNA - SCLC-21H [nTPM]":"11.3","Cell RNA - SH-SY5Y [nTPM]":"11.9","Cell RNA - SiHa [nTPM]":"51.1","Cell RNA - SK-BR-3 [nTPM]":"26.0","Cell RNA - SK-MEL-30 [nTPM]":"25.6","Cell RNA - SuSa [nTPM]":"29.5","Cell RNA - T-47d [nTPM]":"17.8","Cell RNA - THP-1 [nTPM]":"33.9","Cell RNA - TIME [nTPM]":"31.3","Cell RNA - U-138 MG [nTPM]":"20.3","Cell RNA - U-2 OS [nTPM]":"24.8","Cell RNA - U-2197 [nTPM]":"16.3","Cell RNA - U-251 MG [nTPM]":"20.8","Cell RNA - U-266\/70 [nTPM]":"28.5","Cell RNA - U-266\/84 [nTPM]":"14.1","Cell RNA - U-698 [nTPM]":"47.9","Cell RNA - U-87 MG [nTPM]":"16.3","Cell RNA - U-937 [nTPM]":"17.4","Cell RNA - WM-115 [nTPM]":"21.5","Blood RNA - basophil [nTPM]":"3.6","Blood RNA - classical monocyte [nTPM]":"1.7","Blood RNA - eosinophil [nTPM]":"1.6","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"1.9","Blood RNA - MAIT T-cell [nTPM]":"1.5","Blood RNA - memory B-cell [nTPM]":"2.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.7","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"2.1","Blood RNA - naive B-cell [nTPM]":"1.4","Blood RNA - naive CD4 T-cell [nTPM]":"1.4","Blood RNA - naive CD8 T-cell [nTPM]":"1.1","Blood RNA - neutrophil [nTPM]":"4.9","Blood RNA - NK-cell [nTPM]":"2.7","Blood RNA - non-classical monocyte [nTPM]":"1.0","Blood RNA - plasmacytoid DC [nTPM]":"1.6","Blood RNA - T-reg [nTPM]":"1.4","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"6.8","Brain RNA - basal ganglia [nTPM]":"8.9","Brain RNA - cerebellum [nTPM]":"20.5","Brain RNA - cerebral cortex [nTPM]":"10.8","Brain RNA - hippocampal formation [nTPM]":"7.1","Brain RNA - hypothalamus [nTPM]":"9.4","Brain RNA - medulla oblongata [nTPM]":"10.6","Brain RNA - midbrain [nTPM]":"7.8","Brain RNA - pons [nTPM]":"7.7","Brain RNA - spinal cord [nTPM]":"5.3","Brain RNA - thalamus [nTPM]":"8.6","Brain RNA - white matter [nTPM]":"11.2","Single Cell Type RNA - Adipocytes [nTPM]":"45.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"67.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"49.2","Single Cell Type RNA - Astrocytes [nTPM]":"58.1","Single Cell Type RNA - B-cells [nTPM]":"53.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"24.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"40.9","Single Cell Type RNA - Bipolar cells [nTPM]":"44.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"35.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"25.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"31.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"15.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.4","Single Cell Type RNA - dendritic cells [nTPM]":"63.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"37.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"16.1","Single Cell Type RNA - Early spermatids [nTPM]":"15.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"55.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"56.4","Single Cell Type RNA - Endothelial cells [nTPM]":"36.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"24.7","Single Cell Type RNA - Erythroid cells [nTPM]":"60.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"71.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.9","Single Cell Type RNA - Fibroblasts [nTPM]":"32.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"27.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"72.5","Single Cell Type RNA - granulocytes [nTPM]":"25.3","Single Cell Type RNA - Granulosa cells [nTPM]":"36.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.9","Single Cell Type RNA - Hepatocytes [nTPM]":"29.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.4","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"73.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.2","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"60.7","Single Cell Type RNA - Langerhans cells [nTPM]":"25.7","Single Cell Type RNA - Late spermatids [nTPM]":"6.4","Single Cell Type RNA - Leydig cells [nTPM]":"28.9","Single Cell Type RNA - Macrophages [nTPM]":"60.5","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"45.9","Single Cell Type RNA - monocytes [nTPM]":"52.0","Single Cell Type RNA - Muller glia cells [nTPM]":"27.7","Single Cell Type RNA - NK-cells [nTPM]":"40.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"81.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"80.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"25.8","Single Cell Type RNA - Paneth cells [nTPM]":"28.9","Single Cell Type RNA - Peritubular cells [nTPM]":"30.5","Single Cell Type RNA - Plasma cells [nTPM]":"51.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"30.9","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"47.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"36.7","Single Cell Type RNA - Spermatocytes [nTPM]":"22.8","Single Cell Type RNA - Spermatogonia [nTPM]":"31.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"35.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"25.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"30.2","Single Cell Type RNA - T-cells [nTPM]":"46.0","Single Cell Type RNA - Theca cells [nTPM]":"36.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.7","Single Cell Type RNA - Urothelial cells [nTPM]":"36.3"},{"Gene":"EPB41","Gene synonym":["4.1R","EL1"],"Ensembl":"ENSG00000159023","Gene description":"Erythrocyte membrane protein band 4.1","Uniprot":["P11171"],"Chromosome":"1","Position":"28887091-29120046","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cell cycle","Cell division","Mitosis","Transport"],"Molecular function":["Actin-binding","Calmodulin-binding"],"Disease involvement":["Elliptocytosis","Hereditary hemolytic anemia","Pyropoikilocytosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"80.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"151.6","Cone photoreceptor cells":"137.6","Erythroid cells":"187.1","Rod photoreceptor cells":"171.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"42.2"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"136.3","K-562":"136.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"8","RNA pig brain regional specific nTPM":{"cerebellum":"105.6"},"Antibody":["HPA028076","HPA028096","HPA028412","HPA028414"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies","Plasma membrane","Cell Junctions","Cytokinetic bridge","Mitotic spindle","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1100000","Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":["Nuclear bodies","Cytokinetic bridge","Mitotic spindle","Cytosol"],"Antibody RRID":{"HPA028076":"AB_2672476","HPA028096":null,"HPA028412":"AB_2672592","HPA028414":"AB_10601366"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.92e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.58e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.87e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.75e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.0","Tissue RNA - adrenal gland [nTPM]":"10.2","Tissue RNA - amygdala [nTPM]":"1.8","Tissue RNA - appendix [nTPM]":"21.9","Tissue RNA - basal ganglia [nTPM]":"18.3","Tissue RNA - bone marrow [nTPM]":"63.3","Tissue RNA - breast [nTPM]":"14.1","Tissue RNA - cerebellum [nTPM]":"42.2","Tissue RNA - cerebral cortex [nTPM]":"6.0","Tissue RNA - cervix [nTPM]":"14.5","Tissue RNA - choroid plexus [nTPM]":"4.9","Tissue RNA - colon [nTPM]":"23.6","Tissue RNA - duodenum [nTPM]":"17.7","Tissue RNA - endometrium 1 [nTPM]":"10.2","Tissue RNA - epididymis [nTPM]":"5.3","Tissue RNA - esophagus [nTPM]":"16.6","Tissue RNA - fallopian tube [nTPM]":"6.3","Tissue RNA - gallbladder [nTPM]":"15.0","Tissue RNA - heart muscle [nTPM]":"9.7","Tissue RNA - hippocampal formation [nTPM]":"1.2","Tissue RNA - hypothalamus [nTPM]":"4.7","Tissue RNA - kidney [nTPM]":"12.7","Tissue RNA - liver [nTPM]":"21.7","Tissue RNA - lung [nTPM]":"15.1","Tissue RNA - lymph node [nTPM]":"37.4","Tissue RNA - medulla oblongata [nTPM]":"8.2","Tissue RNA - midbrain [nTPM]":"5.6","Tissue RNA - ovary [nTPM]":"16.3","Tissue RNA - pancreas [nTPM]":"18.8","Tissue RNA - parathyroid gland [nTPM]":"15.5","Tissue RNA - pituitary gland [nTPM]":"4.7","Tissue RNA - placenta [nTPM]":"7.2","Tissue RNA - pons [nTPM]":"8.5","Tissue RNA - prostate [nTPM]":"15.0","Tissue RNA - rectum [nTPM]":"23.1","Tissue RNA - retina [nTPM]":"80.0","Tissue RNA - salivary gland [nTPM]":"19.1","Tissue RNA - seminal vesicle [nTPM]":"9.1","Tissue RNA - skeletal muscle [nTPM]":"15.9","Tissue RNA - skin 1 [nTPM]":"15.3","Tissue RNA - small intestine [nTPM]":"23.3","Tissue RNA - smooth muscle [nTPM]":"9.9","Tissue RNA - spinal cord [nTPM]":"3.5","Tissue RNA - spleen [nTPM]":"22.9","Tissue RNA - stomach 1 [nTPM]":"27.0","Tissue RNA - testis [nTPM]":"10.4","Tissue RNA - thalamus [nTPM]":"4.7","Tissue RNA - thymus [nTPM]":"69.0","Tissue RNA - thyroid gland [nTPM]":"15.2","Tissue RNA - tongue [nTPM]":"13.8","Tissue RNA - tonsil [nTPM]":"37.0","Tissue RNA - urinary bladder [nTPM]":"15.5","Tissue RNA - vagina [nTPM]":"1.9","Tissue RNA - white matter [nTPM]":"3.0","Cell RNA - A-431 [nTPM]":"27.0","Cell RNA - A549 [nTPM]":"6.9","Cell RNA - AF22 [nTPM]":"62.3","Cell RNA - AN3-CA [nTPM]":"29.4","Cell RNA - ASC diff [nTPM]":"5.2","Cell RNA - ASC TERT1 [nTPM]":"0.8","Cell RNA - BEWO [nTPM]":"19.5","Cell RNA - BJ [nTPM]":"6.9","Cell RNA - BJ hTERT+ [nTPM]":"10.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.5","Cell RNA - CACO-2 [nTPM]":"16.8","Cell RNA - CAPAN-2 [nTPM]":"31.2","Cell RNA - Daudi [nTPM]":"49.1","Cell RNA - EFO-21 [nTPM]":"17.2","Cell RNA - fHDF\/TERT166 [nTPM]":"9.2","Cell RNA - GAMG [nTPM]":"13.5","Cell RNA - HaCaT [nTPM]":"11.9","Cell RNA - HAP1 [nTPM]":"78.7","Cell RNA - HBEC3-KT [nTPM]":"6.6","Cell RNA - HBF TERT88 [nTPM]":"8.6","Cell RNA - HDLM-2 [nTPM]":"86.4","Cell RNA - HEK 293 [nTPM]":"23.8","Cell RNA - HEL [nTPM]":"136.3","Cell RNA - HeLa [nTPM]":"19.7","Cell RNA - Hep G2 [nTPM]":"28.6","Cell RNA - HHSteC [nTPM]":"10.1","Cell RNA - HL-60 [nTPM]":"45.8","Cell RNA - HMC-1 [nTPM]":"88.2","Cell RNA - HSkMC [nTPM]":"1.7","Cell RNA - hTCEpi [nTPM]":"18.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.2","Cell RNA - hTERT-HME1 [nTPM]":"13.8","Cell RNA - hTERT-RPE1 [nTPM]":"19.9","Cell RNA - HUVEC TERT2 [nTPM]":"14.1","Cell RNA - JURKAT [nTPM]":"73.5","Cell RNA - K-562 [nTPM]":"136.5","Cell RNA - Karpas-707 [nTPM]":"36.2","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"8.8","Cell RNA - MOLT-4 [nTPM]":"72.3","Cell RNA - NB-4 [nTPM]":"30.4","Cell RNA - NTERA-2 [nTPM]":"62.0","Cell RNA - OE19 [nTPM]":"44.1","Cell RNA - PC-3 [nTPM]":"10.0","Cell RNA - REH [nTPM]":"110.9","Cell RNA - RH-30 [nTPM]":"28.2","Cell RNA - RPMI-8226 [nTPM]":"68.3","Cell RNA - RPTEC TERT1 [nTPM]":"7.7","Cell RNA - RT4 [nTPM]":"33.3","Cell RNA - SCLC-21H [nTPM]":"78.0","Cell RNA - SH-SY5Y [nTPM]":"60.5","Cell RNA - SiHa [nTPM]":"19.7","Cell RNA - SK-BR-3 [nTPM]":"19.2","Cell RNA - SK-MEL-30 [nTPM]":"43.3","Cell RNA - SuSa [nTPM]":"21.7","Cell RNA - T-47d [nTPM]":"14.7","Cell RNA - THP-1 [nTPM]":"18.2","Cell RNA - TIME [nTPM]":"1.2","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"13.3","Cell RNA - U-2197 [nTPM]":"12.9","Cell RNA - U-251 MG [nTPM]":"13.4","Cell RNA - U-266\/70 [nTPM]":"52.5","Cell RNA - U-266\/84 [nTPM]":"72.4","Cell RNA - U-698 [nTPM]":"85.2","Cell RNA - U-87 MG [nTPM]":"12.1","Cell RNA - U-937 [nTPM]":"47.8","Cell RNA - WM-115 [nTPM]":"6.8","Blood RNA - basophil [nTPM]":"33.3","Blood RNA - classical monocyte [nTPM]":"3.2","Blood RNA - eosinophil [nTPM]":"21.4","Blood RNA - gdT-cell [nTPM]":"12.9","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"15.4","Blood RNA - memory B-cell [nTPM]":"17.2","Blood RNA - memory CD4 T-cell [nTPM]":"18.3","Blood RNA - memory CD8 T-cell [nTPM]":"14.1","Blood RNA - myeloid DC [nTPM]":"4.4","Blood RNA - naive B-cell [nTPM]":"13.6","Blood RNA - naive CD4 T-cell [nTPM]":"22.1","Blood RNA - naive CD8 T-cell [nTPM]":"12.7","Blood RNA - neutrophil [nTPM]":"44.2","Blood RNA - NK-cell [nTPM]":"10.9","Blood RNA - non-classical monocyte [nTPM]":"1.5","Blood RNA - plasmacytoid DC [nTPM]":"4.4","Blood RNA - T-reg [nTPM]":"28.9","Blood RNA - total PBMC [nTPM]":"15.3","Brain RNA - amygdala [nTPM]":"1.8","Brain RNA - basal ganglia [nTPM]":"18.3","Brain RNA - cerebellum [nTPM]":"42.2","Brain RNA - cerebral cortex [nTPM]":"6.0","Brain RNA - hippocampal formation [nTPM]":"1.2","Brain RNA - hypothalamus [nTPM]":"4.7","Brain RNA - medulla oblongata [nTPM]":"8.2","Brain RNA - midbrain [nTPM]":"5.6","Brain RNA - pons [nTPM]":"8.5","Brain RNA - spinal cord [nTPM]":"3.5","Brain RNA - thalamus [nTPM]":"4.7","Brain RNA - white matter [nTPM]":"3.0","Single Cell Type RNA - Adipocytes [nTPM]":"25.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"71.7","Single Cell Type RNA - Astrocytes [nTPM]":"20.2","Single Cell Type RNA - B-cells [nTPM]":"58.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Bipolar cells [nTPM]":"151.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"20.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"21.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"16.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"137.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.4","Single Cell Type RNA - dendritic cells [nTPM]":"75.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"26.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"17.1","Single Cell Type RNA - Early spermatids [nTPM]":"16.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.1","Single Cell Type RNA - Endothelial cells [nTPM]":"15.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"41.6","Single Cell Type RNA - Erythroid cells [nTPM]":"187.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"76.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.2","Single Cell Type RNA - Fibroblasts [nTPM]":"7.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"29.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"29.1","Single Cell Type RNA - granulocytes [nTPM]":"24.1","Single Cell Type RNA - Granulosa cells [nTPM]":"24.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.5","Single Cell Type RNA - Hepatocytes [nTPM]":"30.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.1","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"61.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"29.0","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"23.7","Single Cell Type RNA - Langerhans cells [nTPM]":"9.0","Single Cell Type RNA - Late spermatids [nTPM]":"22.7","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"32.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"78.7","Single Cell Type RNA - monocytes [nTPM]":"29.3","Single Cell Type RNA - Muller glia cells [nTPM]":"15.7","Single Cell Type RNA - NK-cells [nTPM]":"85.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"28.6","Single Cell Type RNA - Paneth cells [nTPM]":"20.3","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"46.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"32.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"171.4","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.5","Single Cell Type RNA - Spermatocytes [nTPM]":"39.3","Single Cell Type RNA - Spermatogonia [nTPM]":"55.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.1","Single Cell Type RNA - T-cells [nTPM]":"71.6","Single Cell Type RNA - Theca cells [nTPM]":"4.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"33.0","Single Cell Type RNA - Urothelial cells [nTPM]":"12.6"},{"Gene":"EPHA3","Gene synonym":["ETK","ETK1","HEK","HEK4","TYRO4"],"Ensembl":"ENSG00000044524","Gene description":"EPH receptor A3","Uniprot":["P29320"],"Chromosome":"3","Position":"89107621-89482134","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"prostate":"31.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"70.6","Inhibitory neurons":"106.6","Microglial cells":"103.0","Oligodendrocytes":"48.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"AF22":"197.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010462","HPA069390"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane","Plasma membrane","Actin filaments","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nuclear membrane","Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoplasm","Actin filaments"],"Antibody RRID":{"CAB010462":"AB_2099218","HPA069390":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.10e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.28e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.4","Tissue RNA - adrenal gland [nTPM]":"1.0","Tissue RNA - amygdala [nTPM]":"2.1","Tissue RNA - appendix [nTPM]":"1.8","Tissue RNA - basal ganglia [nTPM]":"1.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"2.3","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"3.8","Tissue RNA - cervix [nTPM]":"12.3","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"3.8","Tissue RNA - duodenum [nTPM]":"2.3","Tissue RNA - endometrium 1 [nTPM]":"5.5","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"3.2","Tissue RNA - fallopian tube [nTPM]":"1.3","Tissue RNA - gallbladder [nTPM]":"18.8","Tissue RNA - heart muscle [nTPM]":"8.2","Tissue RNA - hippocampal formation [nTPM]":"2.2","Tissue RNA - hypothalamus [nTPM]":"0.7","Tissue RNA - kidney [nTPM]":"1.3","Tissue RNA - liver [nTPM]":"4.9","Tissue RNA - lung [nTPM]":"2.4","Tissue RNA - lymph node [nTPM]":"3.6","Tissue RNA - medulla oblongata [nTPM]":"3.3","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"4.1","Tissue RNA - pancreas [nTPM]":"2.1","Tissue RNA - parathyroid gland [nTPM]":"1.0","Tissue RNA - pituitary gland [nTPM]":"0.9","Tissue RNA - placenta [nTPM]":"20.1","Tissue RNA - pons [nTPM]":"4.0","Tissue RNA - prostate [nTPM]":"31.5","Tissue RNA - rectum [nTPM]":"6.2","Tissue RNA - retina [nTPM]":"8.0","Tissue RNA - salivary gland [nTPM]":"2.2","Tissue RNA - seminal vesicle [nTPM]":"7.1","Tissue RNA - skeletal muscle [nTPM]":"0.8","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"2.4","Tissue RNA - smooth muscle [nTPM]":"7.9","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"0.9","Tissue RNA - stomach 1 [nTPM]":"2.5","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"1.7","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"11.0","Tissue RNA - tongue [nTPM]":"6.3","Tissue RNA - tonsil [nTPM]":"3.2","Tissue RNA - urinary bladder [nTPM]":"14.3","Tissue RNA - vagina [nTPM]":"6.4","Tissue RNA - white matter [nTPM]":"2.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"197.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"6.6","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"11.2","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.7","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"2.4","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"11.8","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"1.7","Cell RNA - hTERT-RPE1 [nTPM]":"2.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"3.9","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.6","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"2.5","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"2.6","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"2.2","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.5","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"36.1","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.7","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.1","Brain RNA - basal ganglia [nTPM]":"1.3","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"3.8","Brain RNA - hippocampal formation [nTPM]":"2.2","Brain RNA - hypothalamus [nTPM]":"0.7","Brain RNA - medulla oblongata [nTPM]":"3.3","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"4.0","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"1.7","Brain RNA - white matter [nTPM]":"2.2","Single Cell Type RNA - Adipocytes [nTPM]":"2.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"6.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"70.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"18.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"106.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"103.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"48.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"8.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"1.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"EPHB2","Gene synonym":["DRT","EPHT3","ERK","Hek5","Tyro5"],"Ensembl":"ENSG00000133216","Gene description":"EPH receptor B2","Uniprot":["P29323"],"Chromosome":"1","Position":"22710839-22921500","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Neurogenesis"],"Molecular function":["Developmental protein","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"23.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"45.1","Enteroendocrine cells":"48.7","Intestinal goblet cells":"61.1","Oligodendrocytes":"76.3","Pancreatic endocrine cells":"63.7","Undifferentiated cells":"97.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"23.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"GAMG":"86.5","HUVEC TERT2":"74.2","TIME":"79.2","U-251 MG":"69.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013647","HPA071200"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"380000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB013647":null,"HPA071200":"AB_2686360"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.98e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.05e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.1","Tissue RNA - adrenal gland [nTPM]":"1.6","Tissue RNA - amygdala [nTPM]":"2.1","Tissue RNA - appendix [nTPM]":"9.2","Tissue RNA - basal ganglia [nTPM]":"3.7","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"1.6","Tissue RNA - cerebellum [nTPM]":"4.1","Tissue RNA - cerebral cortex [nTPM]":"4.2","Tissue RNA - cervix [nTPM]":"2.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"22.6","Tissue RNA - duodenum [nTPM]":"21.0","Tissue RNA - endometrium 1 [nTPM]":"1.8","Tissue RNA - epididymis [nTPM]":"1.9","Tissue RNA - esophagus [nTPM]":"0.6","Tissue RNA - fallopian tube [nTPM]":"4.4","Tissue RNA - gallbladder [nTPM]":"3.7","Tissue RNA - heart muscle [nTPM]":"3.3","Tissue RNA - hippocampal formation [nTPM]":"2.2","Tissue RNA - hypothalamus [nTPM]":"4.3","Tissue RNA - kidney [nTPM]":"3.8","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"1.8","Tissue RNA - lymph node [nTPM]":"2.9","Tissue RNA - medulla oblongata [nTPM]":"5.7","Tissue RNA - midbrain [nTPM]":"4.5","Tissue RNA - ovary [nTPM]":"10.6","Tissue RNA - pancreas [nTPM]":"3.9","Tissue RNA - parathyroid gland [nTPM]":"6.1","Tissue RNA - pituitary gland [nTPM]":"2.9","Tissue RNA - placenta [nTPM]":"4.0","Tissue RNA - pons [nTPM]":"4.8","Tissue RNA - prostate [nTPM]":"1.9","Tissue RNA - rectum [nTPM]":"23.3","Tissue RNA - retina [nTPM]":"2.9","Tissue RNA - salivary gland [nTPM]":"1.5","Tissue RNA - seminal vesicle [nTPM]":"3.0","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"21.8","Tissue RNA - smooth muscle [nTPM]":"3.3","Tissue RNA - spinal cord [nTPM]":"5.0","Tissue RNA - spleen [nTPM]":"2.4","Tissue RNA - stomach 1 [nTPM]":"1.7","Tissue RNA - testis [nTPM]":"1.8","Tissue RNA - thalamus [nTPM]":"5.4","Tissue RNA - thymus [nTPM]":"1.2","Tissue RNA - thyroid gland [nTPM]":"7.3","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"1.7","Tissue RNA - urinary bladder [nTPM]":"4.4","Tissue RNA - vagina [nTPM]":"1.0","Tissue RNA - white matter [nTPM]":"8.2","Cell RNA - A-431 [nTPM]":"43.4","Cell RNA - A549 [nTPM]":"17.2","Cell RNA - AF22 [nTPM]":"17.2","Cell RNA - AN3-CA [nTPM]":"27.7","Cell RNA - ASC diff [nTPM]":"1.6","Cell RNA - ASC TERT1 [nTPM]":"1.5","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"10.0","Cell RNA - BJ hTERT+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"27.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.7","Cell RNA - CACO-2 [nTPM]":"6.3","Cell RNA - CAPAN-2 [nTPM]":"16.6","Cell RNA - Daudi [nTPM]":"0.6","Cell RNA - EFO-21 [nTPM]":"20.2","Cell RNA - fHDF\/TERT166 [nTPM]":"4.0","Cell RNA - GAMG [nTPM]":"86.5","Cell RNA - HaCaT [nTPM]":"39.6","Cell RNA - HAP1 [nTPM]":"10.8","Cell RNA - HBEC3-KT [nTPM]":"52.8","Cell RNA - HBF TERT88 [nTPM]":"7.7","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"4.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"1.9","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"16.5","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"4.3","Cell RNA - HSkMC [nTPM]":"5.3","Cell RNA - hTCEpi [nTPM]":"17.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"48.7","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"25.4","Cell RNA - HUVEC TERT2 [nTPM]":"74.2","Cell RNA - JURKAT [nTPM]":"2.4","Cell RNA - K-562 [nTPM]":"1.8","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"5.7","Cell RNA - MCF7 [nTPM]":"6.4","Cell RNA - MOLT-4 [nTPM]":"1.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"4.0","Cell RNA - OE19 [nTPM]":"49.0","Cell RNA - PC-3 [nTPM]":"11.2","Cell RNA - REH [nTPM]":"5.3","Cell RNA - RH-30 [nTPM]":"18.0","Cell RNA - RPMI-8226 [nTPM]":"0.8","Cell RNA - RPTEC TERT1 [nTPM]":"14.7","Cell RNA - RT4 [nTPM]":"4.0","Cell RNA - SCLC-21H [nTPM]":"18.0","Cell RNA - SH-SY5Y [nTPM]":"19.3","Cell RNA - SiHa [nTPM]":"17.4","Cell RNA - SK-BR-3 [nTPM]":"0.7","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"1.5","Cell RNA - T-47d [nTPM]":"1.1","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"79.2","Cell RNA - U-138 MG [nTPM]":"11.5","Cell RNA - U-2 OS [nTPM]":"29.6","Cell RNA - U-2197 [nTPM]":"29.4","Cell RNA - U-251 MG [nTPM]":"69.5","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"21.8","Cell RNA - U-937 [nTPM]":"0.9","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"2.1","Brain RNA - basal ganglia [nTPM]":"3.7","Brain RNA - cerebellum [nTPM]":"4.1","Brain RNA - cerebral cortex [nTPM]":"4.2","Brain RNA - hippocampal formation [nTPM]":"2.2","Brain RNA - hypothalamus [nTPM]":"4.3","Brain RNA - medulla oblongata [nTPM]":"5.7","Brain RNA - midbrain [nTPM]":"4.5","Brain RNA - pons [nTPM]":"4.8","Brain RNA - spinal cord [nTPM]":"5.0","Brain RNA - thalamus [nTPM]":"5.4","Brain RNA - white matter [nTPM]":"8.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"20.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"15.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"8.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"45.1","Single Cell Type RNA - Early spermatids [nTPM]":"2.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.8","Single Cell Type RNA - Endothelial cells [nTPM]":"1.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"48.7","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"34.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.8","Single Cell Type RNA - Fibroblasts [nTPM]":"5.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.6","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"32.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"61.1","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"7.6","Single Cell Type RNA - Langerhans cells [nTPM]":"1.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"7.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"18.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"76.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"63.7","Single Cell Type RNA - Paneth cells [nTPM]":"12.6","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"3.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"97.2","Single Cell Type RNA - Urothelial cells [nTPM]":"1.1"},{"Gene":"EPHB4","Gene synonym":["HTK","Tyro11"],"Ensembl":"ENSG00000196411","Gene description":"EPH receptor B4","Uniprot":["P54760"],"Chromosome":"7","Position":"100802565-100827523","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Angiogenesis"],"Molecular function":["Developmental protein","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"68.5","Hepatic stellate cells":"113.2","Syncytiotrophoblasts":"206.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"2.0","neutrophil":"4.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013537"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1400000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB013537":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.56e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.33e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.51e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.84e-4"},"Tissue RNA - adipose tissue [nTPM]":"26.4","Tissue RNA - adrenal gland [nTPM]":"49.8","Tissue RNA - amygdala [nTPM]":"5.0","Tissue RNA - appendix [nTPM]":"8.0","Tissue RNA - basal ganglia [nTPM]":"4.3","Tissue RNA - bone marrow [nTPM]":"5.6","Tissue RNA - breast [nTPM]":"32.6","Tissue RNA - cerebellum [nTPM]":"4.6","Tissue RNA - cerebral cortex [nTPM]":"4.8","Tissue RNA - cervix [nTPM]":"45.6","Tissue RNA - choroid plexus [nTPM]":"6.8","Tissue RNA - colon [nTPM]":"20.7","Tissue RNA - duodenum [nTPM]":"8.3","Tissue RNA - endometrium 1 [nTPM]":"61.5","Tissue RNA - epididymis [nTPM]":"3.8","Tissue RNA - esophagus [nTPM]":"24.7","Tissue RNA - fallopian tube [nTPM]":"27.1","Tissue RNA - gallbladder [nTPM]":"18.0","Tissue RNA - heart muscle [nTPM]":"26.1","Tissue RNA - hippocampal formation [nTPM]":"4.1","Tissue RNA - hypothalamus [nTPM]":"4.1","Tissue RNA - kidney [nTPM]":"28.3","Tissue RNA - liver [nTPM]":"33.3","Tissue RNA - lung [nTPM]":"28.2","Tissue RNA - lymph node [nTPM]":"5.8","Tissue RNA - medulla oblongata [nTPM]":"5.5","Tissue RNA - midbrain [nTPM]":"5.1","Tissue RNA - ovary [nTPM]":"36.0","Tissue RNA - pancreas [nTPM]":"26.8","Tissue RNA - parathyroid gland [nTPM]":"10.1","Tissue RNA - pituitary gland [nTPM]":"6.3","Tissue RNA - placenta [nTPM]":"35.5","Tissue RNA - pons [nTPM]":"5.3","Tissue RNA - prostate [nTPM]":"28.9","Tissue RNA - rectum [nTPM]":"10.2","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"24.2","Tissue RNA - seminal vesicle [nTPM]":"22.4","Tissue RNA - skeletal muscle [nTPM]":"7.7","Tissue RNA - skin 1 [nTPM]":"35.8","Tissue RNA - small intestine [nTPM]":"17.5","Tissue RNA - smooth muscle [nTPM]":"22.2","Tissue RNA - spinal cord [nTPM]":"5.1","Tissue RNA - spleen [nTPM]":"47.9","Tissue RNA - stomach 1 [nTPM]":"21.4","Tissue RNA - testis [nTPM]":"12.3","Tissue RNA - thalamus [nTPM]":"6.3","Tissue RNA - thymus [nTPM]":"3.1","Tissue RNA - thyroid gland [nTPM]":"17.6","Tissue RNA - tongue [nTPM]":"13.3","Tissue RNA - tonsil [nTPM]":"4.9","Tissue RNA - urinary bladder [nTPM]":"17.3","Tissue RNA - vagina [nTPM]":"28.1","Tissue RNA - white matter [nTPM]":"4.8","Cell RNA - A-431 [nTPM]":"37.7","Cell RNA - A549 [nTPM]":"33.1","Cell RNA - AF22 [nTPM]":"32.5","Cell RNA - AN3-CA [nTPM]":"94.2","Cell RNA - ASC diff [nTPM]":"20.4","Cell RNA - ASC TERT1 [nTPM]":"13.0","Cell RNA - BEWO [nTPM]":"94.7","Cell RNA - BJ [nTPM]":"14.1","Cell RNA - BJ hTERT+ [nTPM]":"31.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"22.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"29.0","Cell RNA - CACO-2 [nTPM]":"27.4","Cell RNA - CAPAN-2 [nTPM]":"28.3","Cell RNA - Daudi [nTPM]":"4.8","Cell RNA - EFO-21 [nTPM]":"63.6","Cell RNA - fHDF\/TERT166 [nTPM]":"15.3","Cell RNA - GAMG [nTPM]":"31.3","Cell RNA - HaCaT [nTPM]":"38.2","Cell RNA - HAP1 [nTPM]":"14.3","Cell RNA - HBEC3-KT [nTPM]":"38.3","Cell RNA - HBF TERT88 [nTPM]":"11.9","Cell RNA - HDLM-2 [nTPM]":"6.2","Cell RNA - HEK 293 [nTPM]":"25.6","Cell RNA - HEL [nTPM]":"1.3","Cell RNA - HeLa [nTPM]":"19.0","Cell RNA - Hep G2 [nTPM]":"43.2","Cell RNA - HHSteC [nTPM]":"11.8","Cell RNA - HL-60 [nTPM]":"0.7","Cell RNA - HMC-1 [nTPM]":"0.9","Cell RNA - HSkMC [nTPM]":"15.3","Cell RNA - hTCEpi [nTPM]":"56.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.2","Cell RNA - hTERT-HME1 [nTPM]":"33.1","Cell RNA - hTERT-RPE1 [nTPM]":"24.8","Cell RNA - HUVEC TERT2 [nTPM]":"84.0","Cell RNA - JURKAT [nTPM]":"1.5","Cell RNA - K-562 [nTPM]":"71.9","Cell RNA - Karpas-707 [nTPM]":"1.8","Cell RNA - LHCN-M2 [nTPM]":"18.4","Cell RNA - MCF7 [nTPM]":"66.4","Cell RNA - MOLT-4 [nTPM]":"0.7","Cell RNA - NB-4 [nTPM]":"15.0","Cell RNA - NTERA-2 [nTPM]":"54.7","Cell RNA - OE19 [nTPM]":"56.3","Cell RNA - PC-3 [nTPM]":"47.5","Cell RNA - REH [nTPM]":"51.4","Cell RNA - RH-30 [nTPM]":"15.6","Cell RNA - RPMI-8226 [nTPM]":"8.9","Cell RNA - RPTEC TERT1 [nTPM]":"28.6","Cell RNA - RT4 [nTPM]":"19.9","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"27.4","Cell RNA - SiHa [nTPM]":"22.0","Cell RNA - SK-BR-3 [nTPM]":"10.4","Cell RNA - SK-MEL-30 [nTPM]":"22.1","Cell RNA - SuSa [nTPM]":"45.1","Cell RNA - T-47d [nTPM]":"26.1","Cell RNA - THP-1 [nTPM]":"6.7","Cell RNA - TIME [nTPM]":"71.3","Cell RNA - U-138 MG [nTPM]":"27.6","Cell RNA - U-2 OS [nTPM]":"42.6","Cell RNA - U-2197 [nTPM]":"51.3","Cell RNA - U-251 MG [nTPM]":"21.4","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.8","Cell RNA - U-698 [nTPM]":"1.7","Cell RNA - U-87 MG [nTPM]":"4.0","Cell RNA - U-937 [nTPM]":"12.0","Cell RNA - WM-115 [nTPM]":"51.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.9","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"4.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"5.0","Brain RNA - basal ganglia [nTPM]":"4.3","Brain RNA - cerebellum [nTPM]":"4.6","Brain RNA - cerebral cortex [nTPM]":"4.8","Brain RNA - hippocampal formation [nTPM]":"4.1","Brain RNA - hypothalamus [nTPM]":"4.1","Brain RNA - medulla oblongata [nTPM]":"5.5","Brain RNA - midbrain [nTPM]":"5.1","Brain RNA - pons [nTPM]":"5.3","Brain RNA - spinal cord [nTPM]":"5.1","Brain RNA - thalamus [nTPM]":"6.3","Brain RNA - white matter [nTPM]":"4.8","Single Cell Type RNA - Adipocytes [nTPM]":"47.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.6","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"1.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"19.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"8.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"68.5","Single Cell Type RNA - dendritic cells [nTPM]":"1.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"12.3","Single Cell Type RNA - Early spermatids [nTPM]":"28.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.8","Single Cell Type RNA - Endothelial cells [nTPM]":"51.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"10.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.2","Single Cell Type RNA - Fibroblasts [nTPM]":"6.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"10.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"113.2","Single Cell Type RNA - Hepatocytes [nTPM]":"22.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.4","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"4.1","Single Cell Type RNA - Langerhans cells [nTPM]":"3.4","Single Cell Type RNA - Late spermatids [nTPM]":"9.9","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"1.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"1.5","Single Cell Type RNA - Muller glia cells [nTPM]":"1.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.6","Single Cell Type RNA - Paneth cells [nTPM]":"7.6","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"1.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.4","Single Cell Type RNA - Spermatogonia [nTPM]":"10.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"206.5","Single Cell Type RNA - T-cells [nTPM]":"1.2","Single Cell Type RNA - Theca cells [nTPM]":"2.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.9","Single Cell Type RNA - Urothelial cells [nTPM]":"8.0"},{"Gene":"EPHX1","Gene synonym":["EPHX"],"Ensembl":"ENSG00000143819","Gene description":"Epoxide hydrolase 1","Uniprot":["P07099"],"Chromosome":"1","Position":"225810124-225845563","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Aromatic hydrocarbons catabolism","Detoxification"],"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"1178.6","liver":"1705.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"349.9","Hepatocytes":"757.6","Theca cells":"1042.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"liver cancer":"1047.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"2.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"1161.8","SiHa":"413.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020593","HPA048847"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"160000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA020593":"AB_10601373","HPA048847":"AB_2680538"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.02e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.32e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Tissue RNA - adipose tissue [nTPM]":"245.8","Tissue RNA - adrenal gland [nTPM]":"1178.6","Tissue RNA - amygdala [nTPM]":"233.5","Tissue RNA - appendix [nTPM]":"23.6","Tissue RNA - basal ganglia [nTPM]":"252.5","Tissue RNA - bone marrow [nTPM]":"22.7","Tissue RNA - breast [nTPM]":"163.7","Tissue RNA - cerebellum [nTPM]":"239.0","Tissue RNA - cerebral cortex [nTPM]":"249.3","Tissue RNA - cervix [nTPM]":"188.3","Tissue RNA - choroid plexus [nTPM]":"345.8","Tissue RNA - colon [nTPM]":"82.0","Tissue RNA - duodenum [nTPM]":"102.2","Tissue RNA - endometrium 1 [nTPM]":"108.1","Tissue RNA - epididymis [nTPM]":"97.6","Tissue RNA - esophagus [nTPM]":"159.6","Tissue RNA - fallopian tube [nTPM]":"153.8","Tissue RNA - gallbladder [nTPM]":"96.5","Tissue RNA - heart muscle [nTPM]":"94.0","Tissue RNA - hippocampal formation [nTPM]":"221.3","Tissue RNA - hypothalamus [nTPM]":"233.7","Tissue RNA - kidney [nTPM]":"110.7","Tissue RNA - liver [nTPM]":"1705.1","Tissue RNA - lung [nTPM]":"146.8","Tissue RNA - lymph node [nTPM]":"39.1","Tissue RNA - medulla oblongata [nTPM]":"225.3","Tissue RNA - midbrain [nTPM]":"234.9","Tissue RNA - ovary [nTPM]":"329.1","Tissue RNA - pancreas [nTPM]":"536.1","Tissue RNA - parathyroid gland [nTPM]":"147.7","Tissue RNA - pituitary gland [nTPM]":"105.8","Tissue RNA - placenta [nTPM]":"32.9","Tissue RNA - pons [nTPM]":"223.6","Tissue RNA - prostate [nTPM]":"113.2","Tissue RNA - rectum [nTPM]":"52.5","Tissue RNA - retina [nTPM]":"30.7","Tissue RNA - salivary gland [nTPM]":"143.6","Tissue RNA - seminal vesicle [nTPM]":"128.1","Tissue RNA - skeletal muscle [nTPM]":"142.5","Tissue RNA - skin 1 [nTPM]":"71.5","Tissue RNA - small intestine [nTPM]":"52.8","Tissue RNA - smooth muscle [nTPM]":"109.6","Tissue RNA - spinal cord [nTPM]":"210.1","Tissue RNA - spleen [nTPM]":"55.7","Tissue RNA - stomach 1 [nTPM]":"99.9","Tissue RNA - testis [nTPM]":"74.3","Tissue RNA - thalamus [nTPM]":"258.4","Tissue RNA - thymus [nTPM]":"25.9","Tissue RNA - thyroid gland [nTPM]":"171.1","Tissue RNA - tongue [nTPM]":"95.6","Tissue RNA - tonsil [nTPM]":"33.4","Tissue RNA - urinary bladder [nTPM]":"135.4","Tissue RNA - vagina [nTPM]":"140.4","Tissue RNA - white matter [nTPM]":"227.2","Cell RNA - A-431 [nTPM]":"32.1","Cell RNA - A549 [nTPM]":"202.3","Cell RNA - AF22 [nTPM]":"12.3","Cell RNA - AN3-CA [nTPM]":"108.5","Cell RNA - ASC diff [nTPM]":"1161.8","Cell RNA - ASC TERT1 [nTPM]":"120.2","Cell RNA - BEWO [nTPM]":"24.3","Cell RNA - BJ [nTPM]":"29.7","Cell RNA - BJ hTERT+ [nTPM]":"49.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"28.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"35.1","Cell RNA - CACO-2 [nTPM]":"38.8","Cell RNA - CAPAN-2 [nTPM]":"293.6","Cell RNA - Daudi [nTPM]":"1.3","Cell RNA - EFO-21 [nTPM]":"128.7","Cell RNA - fHDF\/TERT166 [nTPM]":"147.3","Cell RNA - GAMG [nTPM]":"30.6","Cell RNA - HaCaT [nTPM]":"38.1","Cell RNA - HAP1 [nTPM]":"32.7","Cell RNA - HBEC3-KT [nTPM]":"16.8","Cell RNA - HBF TERT88 [nTPM]":"12.1","Cell RNA - HDLM-2 [nTPM]":"7.8","Cell RNA - HEK 293 [nTPM]":"46.5","Cell RNA - HEL [nTPM]":"21.8","Cell RNA - HeLa [nTPM]":"83.5","Cell RNA - Hep G2 [nTPM]":"282.7","Cell RNA - HHSteC [nTPM]":"129.8","Cell RNA - HL-60 [nTPM]":"12.9","Cell RNA - HMC-1 [nTPM]":"15.1","Cell RNA - HSkMC [nTPM]":"109.2","Cell RNA - hTCEpi [nTPM]":"40.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"74.6","Cell RNA - hTERT-HME1 [nTPM]":"6.3","Cell RNA - hTERT-RPE1 [nTPM]":"116.5","Cell RNA - HUVEC TERT2 [nTPM]":"22.1","Cell RNA - JURKAT [nTPM]":"13.4","Cell RNA - K-562 [nTPM]":"14.5","Cell RNA - Karpas-707 [nTPM]":"27.3","Cell RNA - LHCN-M2 [nTPM]":"50.4","Cell RNA - MCF7 [nTPM]":"30.3","Cell RNA - MOLT-4 [nTPM]":"13.5","Cell RNA - NB-4 [nTPM]":"31.0","Cell RNA - NTERA-2 [nTPM]":"61.6","Cell RNA - OE19 [nTPM]":"178.1","Cell RNA - PC-3 [nTPM]":"79.4","Cell RNA - REH [nTPM]":"27.8","Cell RNA - RH-30 [nTPM]":"15.2","Cell RNA - RPMI-8226 [nTPM]":"92.9","Cell RNA - RPTEC TERT1 [nTPM]":"91.1","Cell RNA - RT4 [nTPM]":"132.5","Cell RNA - SCLC-21H [nTPM]":"98.3","Cell RNA - SH-SY5Y [nTPM]":"13.0","Cell RNA - SiHa [nTPM]":"413.0","Cell RNA - SK-BR-3 [nTPM]":"192.1","Cell RNA - SK-MEL-30 [nTPM]":"51.3","Cell RNA - SuSa [nTPM]":"32.1","Cell RNA - T-47d [nTPM]":"131.7","Cell RNA - THP-1 [nTPM]":"43.5","Cell RNA - TIME [nTPM]":"46.8","Cell RNA - U-138 MG [nTPM]":"41.9","Cell RNA - U-2 OS [nTPM]":"35.4","Cell RNA - U-2197 [nTPM]":"54.5","Cell RNA - U-251 MG [nTPM]":"59.0","Cell RNA - U-266\/70 [nTPM]":"9.1","Cell RNA - U-266\/84 [nTPM]":"38.9","Cell RNA - U-698 [nTPM]":"4.1","Cell RNA - U-87 MG [nTPM]":"63.5","Cell RNA - U-937 [nTPM]":"14.2","Cell RNA - WM-115 [nTPM]":"59.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.6","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"233.5","Brain RNA - basal ganglia [nTPM]":"252.5","Brain RNA - cerebellum [nTPM]":"239.0","Brain RNA - cerebral cortex [nTPM]":"249.3","Brain RNA - hippocampal formation [nTPM]":"221.3","Brain RNA - hypothalamus [nTPM]":"233.7","Brain RNA - medulla oblongata [nTPM]":"225.3","Brain RNA - midbrain [nTPM]":"234.9","Brain RNA - pons [nTPM]":"223.6","Brain RNA - spinal cord [nTPM]":"210.1","Brain RNA - thalamus [nTPM]":"258.4","Brain RNA - white matter [nTPM]":"227.2","Single Cell Type RNA - Adipocytes [nTPM]":"196.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.0","Single Cell Type RNA - Astrocytes [nTPM]":"41.1","Single Cell Type RNA - B-cells [nTPM]":"5.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"19.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"121.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"244.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"74.0","Single Cell Type RNA - Bipolar cells [nTPM]":"8.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"27.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"102.9","Single Cell Type RNA - Club cells [nTPM]":"255.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"51.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"46.6","Single Cell Type RNA - dendritic cells [nTPM]":"3.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"34.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"95.3","Single Cell Type RNA - Early spermatids [nTPM]":"10.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"142.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"32.2","Single Cell Type RNA - Endothelial cells [nTPM]":"82.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.8","Single Cell Type RNA - Erythroid cells [nTPM]":"7.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"73.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.6","Single Cell Type RNA - Fibroblasts [nTPM]":"175.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"30.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"93.4","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"349.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"88.2","Single Cell Type RNA - Hepatocytes [nTPM]":"757.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"149.1","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.5","Single Cell Type RNA - Ionocytes [nTPM]":"103.7","Single Cell Type RNA - Kupffer cells [nTPM]":"30.9","Single Cell Type RNA - Langerhans cells [nTPM]":"28.7","Single Cell Type RNA - Late spermatids [nTPM]":"28.4","Single Cell Type RNA - Leydig cells [nTPM]":"311.3","Single Cell Type RNA - Macrophages [nTPM]":"25.8","Single Cell Type RNA - Melanocytes [nTPM]":"42.7","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"9.6","Single Cell Type RNA - Muller glia cells [nTPM]":"99.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"45.5","Single Cell Type RNA - Paneth cells [nTPM]":"27.2","Single Cell Type RNA - Peritubular cells [nTPM]":"159.1","Single Cell Type RNA - Plasma cells [nTPM]":"9.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"40.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"63.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"128.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"174.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.1","Single Cell Type RNA - Sertoli cells [nTPM]":"223.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"29.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"146.9","Single Cell Type RNA - Spermatocytes [nTPM]":"4.4","Single Cell Type RNA - Spermatogonia [nTPM]":"5.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"129.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.8","Single Cell Type RNA - T-cells [nTPM]":"4.7","Single Cell Type RNA - Theca cells [nTPM]":"1042.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"31.5","Single Cell Type RNA - Urothelial cells [nTPM]":"108.5"},{"Gene":"EPM2A","Gene synonym":["LD","LDE"],"Ensembl":"ENSG00000112425","Gene description":"EPM2A glucan phosphatase, laforin","Uniprot":["O95278"],"Chromosome":"6","Position":"145382535-145736023","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Autophagy","Carbohydrate metabolism","Glycogen metabolism"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":["Disease variant","Epilepsy","Glycogen storage disease","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"76.8","tongue":"79.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"66.9","Early spermatids":"33.0","Excitatory neurons":"30.4","Inhibitory neurons":"50.7","Oligodendrocyte precursor cells":"56.8","Oligodendrocytes":"60.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"1.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"23.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053643","HPA055468"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA053643":"AB_2797247","HPA055468":"AB_2797252"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.08e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.8","Tissue RNA - adrenal gland [nTPM]":"6.0","Tissue RNA - amygdala [nTPM]":"11.4","Tissue RNA - appendix [nTPM]":"1.5","Tissue RNA - basal ganglia [nTPM]":"11.7","Tissue RNA - bone marrow [nTPM]":"1.8","Tissue RNA - breast [nTPM]":"3.2","Tissue RNA - cerebellum [nTPM]":"11.9","Tissue RNA - cerebral cortex [nTPM]":"17.8","Tissue RNA - cervix [nTPM]":"3.1","Tissue RNA - choroid plexus [nTPM]":"7.3","Tissue RNA - colon [nTPM]":"17.2","Tissue RNA - duodenum [nTPM]":"3.2","Tissue RNA - endometrium 1 [nTPM]":"6.0","Tissue RNA - epididymis [nTPM]":"4.3","Tissue RNA - esophagus [nTPM]":"9.3","Tissue RNA - fallopian tube [nTPM]":"4.4","Tissue RNA - gallbladder [nTPM]":"3.6","Tissue RNA - heart muscle [nTPM]":"24.4","Tissue RNA - hippocampal formation [nTPM]":"11.6","Tissue RNA - hypothalamus [nTPM]":"12.6","Tissue RNA - kidney [nTPM]":"8.5","Tissue RNA - liver [nTPM]":"5.7","Tissue RNA - lung [nTPM]":"3.0","Tissue RNA - lymph node [nTPM]":"3.3","Tissue RNA - medulla oblongata [nTPM]":"11.9","Tissue RNA - midbrain [nTPM]":"11.5","Tissue RNA - ovary [nTPM]":"5.7","Tissue RNA - pancreas [nTPM]":"2.4","Tissue RNA - parathyroid gland [nTPM]":"5.2","Tissue RNA - pituitary gland [nTPM]":"3.8","Tissue RNA - placenta [nTPM]":"1.5","Tissue RNA - pons [nTPM]":"11.1","Tissue RNA - prostate [nTPM]":"6.1","Tissue RNA - rectum [nTPM]":"2.9","Tissue RNA - retina [nTPM]":"12.1","Tissue RNA - salivary gland [nTPM]":"3.1","Tissue RNA - seminal vesicle [nTPM]":"8.8","Tissue RNA - skeletal muscle [nTPM]":"76.8","Tissue RNA - skin 1 [nTPM]":"2.1","Tissue RNA - small intestine [nTPM]":"3.8","Tissue RNA - smooth muscle [nTPM]":"6.3","Tissue RNA - spinal cord [nTPM]":"10.3","Tissue RNA - spleen [nTPM]":"2.1","Tissue RNA - stomach 1 [nTPM]":"5.3","Tissue RNA - testis [nTPM]":"3.0","Tissue RNA - thalamus [nTPM]":"11.5","Tissue RNA - thymus [nTPM]":"4.8","Tissue RNA - thyroid gland [nTPM]":"3.9","Tissue RNA - tongue [nTPM]":"79.5","Tissue RNA - tonsil [nTPM]":"2.6","Tissue RNA - urinary bladder [nTPM]":"9.8","Tissue RNA - vagina [nTPM]":"2.7","Tissue RNA - white matter [nTPM]":"13.3","Cell RNA - A-431 [nTPM]":"1.3","Cell RNA - A549 [nTPM]":"2.1","Cell RNA - AF22 [nTPM]":"3.4","Cell RNA - AN3-CA [nTPM]":"6.6","Cell RNA - ASC diff [nTPM]":"8.6","Cell RNA - ASC TERT1 [nTPM]":"2.3","Cell RNA - BEWO [nTPM]":"1.6","Cell RNA - BJ [nTPM]":"3.1","Cell RNA - BJ hTERT+ [nTPM]":"3.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.5","Cell RNA - CACO-2 [nTPM]":"1.7","Cell RNA - CAPAN-2 [nTPM]":"1.7","Cell RNA - Daudi [nTPM]":"23.2","Cell RNA - EFO-21 [nTPM]":"2.7","Cell RNA - fHDF\/TERT166 [nTPM]":"3.8","Cell RNA - GAMG [nTPM]":"3.5","Cell RNA - HaCaT [nTPM]":"1.8","Cell RNA - HAP1 [nTPM]":"1.3","Cell RNA - HBEC3-KT [nTPM]":"1.6","Cell RNA - HBF TERT88 [nTPM]":"2.6","Cell RNA - HDLM-2 [nTPM]":"9.3","Cell RNA - HEK 293 [nTPM]":"1.9","Cell RNA - HEL [nTPM]":"3.6","Cell RNA - HeLa [nTPM]":"2.5","Cell RNA - Hep G2 [nTPM]":"2.7","Cell RNA - HHSteC [nTPM]":"4.8","Cell RNA - HL-60 [nTPM]":"12.7","Cell RNA - HMC-1 [nTPM]":"2.4","Cell RNA - HSkMC [nTPM]":"2.0","Cell RNA - hTCEpi [nTPM]":"7.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.7","Cell RNA - hTERT-HME1 [nTPM]":"0.7","Cell RNA - hTERT-RPE1 [nTPM]":"3.8","Cell RNA - HUVEC TERT2 [nTPM]":"2.0","Cell RNA - JURKAT [nTPM]":"5.0","Cell RNA - K-562 [nTPM]":"1.8","Cell RNA - Karpas-707 [nTPM]":"5.4","Cell RNA - LHCN-M2 [nTPM]":"3.8","Cell RNA - MCF7 [nTPM]":"3.1","Cell RNA - MOLT-4 [nTPM]":"8.4","Cell RNA - NB-4 [nTPM]":"3.2","Cell RNA - NTERA-2 [nTPM]":"3.9","Cell RNA - OE19 [nTPM]":"3.2","Cell RNA - PC-3 [nTPM]":"1.9","Cell RNA - REH [nTPM]":"4.8","Cell RNA - RH-30 [nTPM]":"3.1","Cell RNA - RPMI-8226 [nTPM]":"6.7","Cell RNA - RPTEC TERT1 [nTPM]":"2.5","Cell RNA - RT4 [nTPM]":"1.8","Cell RNA - SCLC-21H [nTPM]":"6.3","Cell RNA - SH-SY5Y [nTPM]":"6.4","Cell RNA - SiHa [nTPM]":"5.5","Cell RNA - SK-BR-3 [nTPM]":"3.3","Cell RNA - SK-MEL-30 [nTPM]":"7.8","Cell RNA - SuSa [nTPM]":"3.1","Cell RNA - T-47d [nTPM]":"1.9","Cell RNA - THP-1 [nTPM]":"7.3","Cell RNA - TIME [nTPM]":"4.6","Cell RNA - U-138 MG [nTPM]":"2.9","Cell RNA - U-2 OS [nTPM]":"1.1","Cell RNA - U-2197 [nTPM]":"2.7","Cell RNA - U-251 MG [nTPM]":"2.6","Cell RNA - U-266\/70 [nTPM]":"4.1","Cell RNA - U-266\/84 [nTPM]":"4.6","Cell RNA - U-698 [nTPM]":"8.6","Cell RNA - U-87 MG [nTPM]":"2.6","Cell RNA - U-937 [nTPM]":"2.8","Cell RNA - WM-115 [nTPM]":"4.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"1.9","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"11.4","Brain RNA - basal ganglia [nTPM]":"11.7","Brain RNA - cerebellum [nTPM]":"11.9","Brain RNA - cerebral cortex [nTPM]":"17.8","Brain RNA - hippocampal formation [nTPM]":"11.6","Brain RNA - hypothalamus [nTPM]":"12.6","Brain RNA - medulla oblongata [nTPM]":"11.9","Brain RNA - midbrain [nTPM]":"11.5","Brain RNA - pons [nTPM]":"11.1","Brain RNA - spinal cord [nTPM]":"10.3","Brain RNA - thalamus [nTPM]":"11.5","Brain RNA - white matter [nTPM]":"13.3","Single Cell Type RNA - Adipocytes [nTPM]":"3.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.5","Single Cell Type RNA - Astrocytes [nTPM]":"66.9","Single Cell Type RNA - B-cells [nTPM]":"4.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"8.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"27.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"2.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"1.0","Single Cell Type RNA - Early spermatids [nTPM]":"33.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.6","Single Cell Type RNA - Endothelial cells [nTPM]":"2.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"4.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"30.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"2.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.4","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"6.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"6.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.3","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"50.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.5","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1.4","Single Cell Type RNA - Late spermatids [nTPM]":"19.8","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"3.1","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"1.7","Single Cell Type RNA - Muller glia cells [nTPM]":"7.9","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"56.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"60.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.2","Single Cell Type RNA - Paneth cells [nTPM]":"1.7","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"1.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.4","Single Cell Type RNA - Spermatocytes [nTPM]":"4.9","Single Cell Type RNA - Spermatogonia [nTPM]":"1.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"1.8","Single Cell Type RNA - Theca cells [nTPM]":"5.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"EPRS1","Gene synonym":["EARS","EPRS","GLUPRORS","PARS","QARS","QPRS"],"Ensembl":"ENSG00000136628","Gene description":"Glutamyl-prolyl-tRNA synthetase 1","Uniprot":["P07814"],"Chromosome":"1","Position":"219968600-220046530","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis","Translation regulation"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase","Multifunctional enzyme","RNA-binding"],"Disease involvement":["Disease variant","Leukodystrophy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"22.3","Cardiomyocytes":"84.7","Cytotrophoblasts":"40.8","Extravillous trophoblasts":"59.3","Hofbauer cells":"42.6","Syncytiotrophoblasts":"36.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026490","HPA030052"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"360000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA026490":"AB_1855979","HPA030052":"AB_10601466"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.25e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.98e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.62e-4"},"Tissue RNA - adipose tissue [nTPM]":"28.8","Tissue RNA - adrenal gland [nTPM]":"24.7","Tissue RNA - amygdala [nTPM]":"18.1","Tissue RNA - appendix [nTPM]":"34.4","Tissue RNA - basal ganglia [nTPM]":"19.6","Tissue RNA - bone marrow [nTPM]":"26.6","Tissue RNA - breast [nTPM]":"35.7","Tissue RNA - cerebellum [nTPM]":"22.8","Tissue RNA - cerebral cortex [nTPM]":"24.8","Tissue RNA - cervix [nTPM]":"30.5","Tissue RNA - choroid plexus [nTPM]":"17.6","Tissue RNA - colon [nTPM]":"36.1","Tissue RNA - duodenum [nTPM]":"27.7","Tissue RNA - endometrium 1 [nTPM]":"25.6","Tissue RNA - epididymis [nTPM]":"25.2","Tissue RNA - esophagus [nTPM]":"30.6","Tissue RNA - fallopian tube [nTPM]":"26.2","Tissue RNA - gallbladder [nTPM]":"20.6","Tissue RNA - heart muscle [nTPM]":"31.8","Tissue RNA - hippocampal formation [nTPM]":"17.7","Tissue RNA - hypothalamus [nTPM]":"21.8","Tissue RNA - kidney [nTPM]":"31.6","Tissue RNA - liver [nTPM]":"27.9","Tissue RNA - lung [nTPM]":"24.3","Tissue RNA - lymph node [nTPM]":"36.5","Tissue RNA - medulla oblongata [nTPM]":"21.6","Tissue RNA - midbrain [nTPM]":"20.5","Tissue RNA - ovary [nTPM]":"34.7","Tissue RNA - pancreas [nTPM]":"49.0","Tissue RNA - parathyroid gland [nTPM]":"54.5","Tissue RNA - pituitary gland [nTPM]":"22.5","Tissue RNA - placenta [nTPM]":"23.8","Tissue RNA - pons [nTPM]":"22.9","Tissue RNA - prostate [nTPM]":"23.6","Tissue RNA - rectum [nTPM]":"39.0","Tissue RNA - retina [nTPM]":"43.8","Tissue RNA - salivary gland [nTPM]":"83.4","Tissue RNA - seminal vesicle [nTPM]":"26.4","Tissue RNA - skeletal muscle [nTPM]":"52.2","Tissue RNA - skin 1 [nTPM]":"28.9","Tissue RNA - small intestine [nTPM]":"29.7","Tissue RNA - smooth muscle [nTPM]":"32.5","Tissue RNA - spinal cord [nTPM]":"22.4","Tissue RNA - spleen [nTPM]":"27.4","Tissue RNA - stomach 1 [nTPM]":"35.9","Tissue RNA - testis [nTPM]":"20.5","Tissue RNA - thalamus [nTPM]":"21.7","Tissue RNA - thymus [nTPM]":"34.8","Tissue RNA - thyroid gland [nTPM]":"43.0","Tissue RNA - tongue [nTPM]":"55.9","Tissue RNA - tonsil [nTPM]":"42.5","Tissue RNA - urinary bladder [nTPM]":"30.4","Tissue RNA - vagina [nTPM]":"18.6","Tissue RNA - white matter [nTPM]":"27.8","Cell RNA - A-431 [nTPM]":"125.9","Cell RNA - A549 [nTPM]":"78.4","Cell RNA - AF22 [nTPM]":"55.7","Cell RNA - AN3-CA [nTPM]":"152.3","Cell RNA - ASC diff [nTPM]":"114.9","Cell RNA - ASC TERT1 [nTPM]":"126.7","Cell RNA - BEWO [nTPM]":"138.0","Cell RNA - BJ [nTPM]":"160.1","Cell RNA - BJ hTERT+ [nTPM]":"111.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"102.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"113.4","Cell RNA - CACO-2 [nTPM]":"93.3","Cell RNA - CAPAN-2 [nTPM]":"98.1","Cell RNA - Daudi [nTPM]":"239.3","Cell RNA - EFO-21 [nTPM]":"86.7","Cell RNA - fHDF\/TERT166 [nTPM]":"170.4","Cell RNA - GAMG [nTPM]":"41.3","Cell RNA - HaCaT [nTPM]":"130.3","Cell RNA - HAP1 [nTPM]":"140.9","Cell RNA - HBEC3-KT [nTPM]":"129.4","Cell RNA - HBF TERT88 [nTPM]":"136.2","Cell RNA - HDLM-2 [nTPM]":"117.9","Cell RNA - HEK 293 [nTPM]":"88.9","Cell RNA - HEL [nTPM]":"130.2","Cell RNA - HeLa [nTPM]":"97.6","Cell RNA - Hep G2 [nTPM]":"80.2","Cell RNA - HHSteC [nTPM]":"125.1","Cell RNA - HL-60 [nTPM]":"217.6","Cell RNA - HMC-1 [nTPM]":"106.7","Cell RNA - HSkMC [nTPM]":"92.1","Cell RNA - hTCEpi [nTPM]":"161.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"130.3","Cell RNA - hTERT-HME1 [nTPM]":"161.6","Cell RNA - hTERT-RPE1 [nTPM]":"84.8","Cell RNA - HUVEC TERT2 [nTPM]":"113.4","Cell RNA - JURKAT [nTPM]":"113.2","Cell RNA - K-562 [nTPM]":"228.0","Cell RNA - Karpas-707 [nTPM]":"182.9","Cell RNA - LHCN-M2 [nTPM]":"100.8","Cell RNA - MCF7 [nTPM]":"61.8","Cell RNA - MOLT-4 [nTPM]":"94.7","Cell RNA - NB-4 [nTPM]":"53.1","Cell RNA - NTERA-2 [nTPM]":"107.4","Cell RNA - OE19 [nTPM]":"146.8","Cell RNA - PC-3 [nTPM]":"159.6","Cell RNA - REH [nTPM]":"98.5","Cell RNA - RH-30 [nTPM]":"98.0","Cell RNA - RPMI-8226 [nTPM]":"236.2","Cell RNA - RPTEC TERT1 [nTPM]":"92.8","Cell RNA - RT4 [nTPM]":"54.4","Cell RNA - SCLC-21H [nTPM]":"128.6","Cell RNA - SH-SY5Y [nTPM]":"101.3","Cell RNA - SiHa [nTPM]":"93.7","Cell RNA - SK-BR-3 [nTPM]":"152.6","Cell RNA - SK-MEL-30 [nTPM]":"166.5","Cell RNA - SuSa [nTPM]":"78.9","Cell RNA - T-47d [nTPM]":"141.2","Cell RNA - THP-1 [nTPM]":"235.1","Cell RNA - TIME [nTPM]":"101.1","Cell RNA - U-138 MG [nTPM]":"48.3","Cell RNA - U-2 OS [nTPM]":"88.1","Cell RNA - U-2197 [nTPM]":"149.6","Cell RNA - U-251 MG [nTPM]":"151.1","Cell RNA - U-266\/70 [nTPM]":"122.8","Cell RNA - U-266\/84 [nTPM]":"150.1","Cell RNA - U-698 [nTPM]":"197.1","Cell RNA - U-87 MG [nTPM]":"111.4","Cell RNA - U-937 [nTPM]":"153.9","Cell RNA - WM-115 [nTPM]":"156.4","Blood RNA - basophil [nTPM]":"8.8","Blood RNA - classical monocyte [nTPM]":"17.8","Blood RNA - eosinophil [nTPM]":"10.0","Blood RNA - gdT-cell [nTPM]":"19.7","Blood RNA - intermediate monocyte [nTPM]":"24.6","Blood RNA - MAIT T-cell [nTPM]":"27.8","Blood RNA - memory B-cell [nTPM]":"21.0","Blood RNA - memory CD4 T-cell [nTPM]":"19.7","Blood RNA - memory CD8 T-cell [nTPM]":"22.1","Blood RNA - myeloid DC [nTPM]":"23.2","Blood RNA - naive B-cell [nTPM]":"18.5","Blood RNA - naive CD4 T-cell [nTPM]":"22.0","Blood RNA - naive CD8 T-cell [nTPM]":"22.9","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"22.5","Blood RNA - non-classical monocyte [nTPM]":"22.1","Blood RNA - plasmacytoid DC [nTPM]":"7.6","Blood RNA - T-reg [nTPM]":"20.8","Blood RNA - total PBMC [nTPM]":"17.2","Brain RNA - amygdala [nTPM]":"18.1","Brain RNA - basal ganglia [nTPM]":"19.6","Brain RNA - cerebellum [nTPM]":"22.8","Brain RNA - cerebral cortex [nTPM]":"24.8","Brain RNA - hippocampal formation [nTPM]":"17.7","Brain RNA - hypothalamus [nTPM]":"21.8","Brain RNA - medulla oblongata [nTPM]":"21.6","Brain RNA - midbrain [nTPM]":"20.5","Brain RNA - pons [nTPM]":"22.9","Brain RNA - spinal cord [nTPM]":"22.4","Brain RNA - thalamus [nTPM]":"21.7","Brain RNA - white matter [nTPM]":"27.8","Single Cell Type RNA - Adipocytes [nTPM]":"22.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"4.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"84.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"40.8","Single Cell Type RNA - dendritic cells [nTPM]":"14.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"5.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"59.3","Single Cell Type RNA - Fibroblasts [nTPM]":"17.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"42.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"2.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"10.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"36.5","Single Cell Type RNA - T-cells [nTPM]":"2.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"EPX","Gene synonym":["EPO","EPP","EPX-PEN"],"Ensembl":"ENSG00000121053","Gene description":"Eosinophil peroxidase","Uniprot":["P11678"],"Chromosome":"17","Position":"58192726-58205174","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Hydrogen peroxide"],"Molecular function":["Oxidoreductase","Peroxidase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"17","RNA tissue specific nTPM":{"bone marrow":"33.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"1.5","Inhibitory neurons":"1.2","Microglial cells":"1.0","Oligodendrocyte precursor cells":"2.0","Oligodendrocytes":"1.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"23","RNA blood cell specific nTPM":{"eosinophil":"2.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"23","RNA blood lineage specific nTPM":{"granulocytes":"2.2"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"68","RNA cell line specific nTPM":{"NB-4":"248.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA076792"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA076792":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"33.7","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"1.3","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"2.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.9","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"3.6","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.9","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"248.2","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"2.9","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"2.2","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"ERBB3","Gene synonym":["HER3","LCCS2"],"Ensembl":"ENSG00000065361","Gene description":"Erb-b2 receptor tyrosine kinase 3","Uniprot":["P21860"],"Chromosome":"12","Position":"56076799-56103505","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"254.3","Oligodendrocytes":"187.0","Paneth cells":"184.6","Proximal enterocytes":"240.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"2.4","neutrophil":"1.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"2.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"116.4","OE19":"119.1","RT4":"89.7","SK-BR-3":"106.5","SK-MEL-30":"149.5","T-47d":"122.2","WM-115":"153.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025331","HPA045396","HPA070524"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Actin filaments"],"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"450000","Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Actin filaments"],"Antibody RRID":{"CAB025331":null,"HPA045396":"AB_2679312","HPA070524":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.72e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.4","Tissue RNA - adrenal gland [nTPM]":"2.6","Tissue RNA - amygdala [nTPM]":"34.4","Tissue RNA - appendix [nTPM]":"8.0","Tissue RNA - basal ganglia [nTPM]":"69.2","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"56.5","Tissue RNA - cerebellum [nTPM]":"45.9","Tissue RNA - cerebral cortex [nTPM]":"62.0","Tissue RNA - cervix [nTPM]":"20.9","Tissue RNA - choroid plexus [nTPM]":"10.9","Tissue RNA - colon [nTPM]":"62.9","Tissue RNA - duodenum [nTPM]":"88.5","Tissue RNA - endometrium 1 [nTPM]":"5.5","Tissue RNA - epididymis [nTPM]":"12.3","Tissue RNA - esophagus [nTPM]":"82.0","Tissue RNA - fallopian tube [nTPM]":"12.1","Tissue RNA - gallbladder [nTPM]":"30.6","Tissue RNA - heart muscle [nTPM]":"9.0","Tissue RNA - hippocampal formation [nTPM]":"39.2","Tissue RNA - hypothalamus [nTPM]":"43.1","Tissue RNA - kidney [nTPM]":"36.2","Tissue RNA - liver [nTPM]":"98.6","Tissue RNA - lung [nTPM]":"29.3","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"59.4","Tissue RNA - midbrain [nTPM]":"54.4","Tissue RNA - ovary [nTPM]":"1.6","Tissue RNA - pancreas [nTPM]":"57.0","Tissue RNA - parathyroid gland [nTPM]":"23.8","Tissue RNA - pituitary gland [nTPM]":"2.4","Tissue RNA - placenta [nTPM]":"13.0","Tissue RNA - pons [nTPM]":"54.7","Tissue RNA - prostate [nTPM]":"37.8","Tissue RNA - rectum [nTPM]":"64.1","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"83.0","Tissue RNA - seminal vesicle [nTPM]":"18.2","Tissue RNA - skeletal muscle [nTPM]":"2.4","Tissue RNA - skin 1 [nTPM]":"75.7","Tissue RNA - small intestine [nTPM]":"82.5","Tissue RNA - smooth muscle [nTPM]":"3.8","Tissue RNA - spinal cord [nTPM]":"36.2","Tissue RNA - spleen [nTPM]":"0.6","Tissue RNA - stomach 1 [nTPM]":"74.7","Tissue RNA - testis [nTPM]":"2.3","Tissue RNA - thalamus [nTPM]":"55.9","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"9.4","Tissue RNA - tongue [nTPM]":"1.7","Tissue RNA - tonsil [nTPM]":"12.5","Tissue RNA - urinary bladder [nTPM]":"21.8","Tissue RNA - vagina [nTPM]":"44.2","Tissue RNA - white matter [nTPM]":"104.9","Cell RNA - A-431 [nTPM]":"39.8","Cell RNA - A549 [nTPM]":"2.1","Cell RNA - AF22 [nTPM]":"3.2","Cell RNA - AN3-CA [nTPM]":"1.4","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"63.2","Cell RNA - BJ [nTPM]":"3.9","Cell RNA - BJ hTERT+ [nTPM]":"7.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.1","Cell RNA - CACO-2 [nTPM]":"20.4","Cell RNA - CAPAN-2 [nTPM]":"70.4","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.8","Cell RNA - fHDF\/TERT166 [nTPM]":"1.0","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"32.2","Cell RNA - HAP1 [nTPM]":"5.0","Cell RNA - HBEC3-KT [nTPM]":"7.7","Cell RNA - HBF TERT88 [nTPM]":"2.3","Cell RNA - HDLM-2 [nTPM]":"0.7","Cell RNA - HEK 293 [nTPM]":"3.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"1.1","Cell RNA - Hep G2 [nTPM]":"116.4","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"1.3","Cell RNA - hTCEpi [nTPM]":"9.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.7","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.8","Cell RNA - K-562 [nTPM]":"2.6","Cell RNA - Karpas-707 [nTPM]":"1.0","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"71.6","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"1.3","Cell RNA - NTERA-2 [nTPM]":"10.4","Cell RNA - OE19 [nTPM]":"119.1","Cell RNA - PC-3 [nTPM]":"1.9","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"7.4","Cell RNA - RPMI-8226 [nTPM]":"2.1","Cell RNA - RPTEC TERT1 [nTPM]":"7.9","Cell RNA - RT4 [nTPM]":"89.7","Cell RNA - SCLC-21H [nTPM]":"3.3","Cell RNA - SH-SY5Y [nTPM]":"1.3","Cell RNA - SiHa [nTPM]":"2.6","Cell RNA - SK-BR-3 [nTPM]":"106.5","Cell RNA - SK-MEL-30 [nTPM]":"149.5","Cell RNA - SuSa [nTPM]":"9.1","Cell RNA - T-47d [nTPM]":"122.2","Cell RNA - THP-1 [nTPM]":"0.7","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.5","Cell RNA - U-2 OS [nTPM]":"4.0","Cell RNA - U-2197 [nTPM]":"1.9","Cell RNA - U-251 MG [nTPM]":"0.5","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"0.6","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"153.4","Blood RNA - basophil [nTPM]":"2.4","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"34.4","Brain RNA - basal ganglia [nTPM]":"69.2","Brain RNA - cerebellum [nTPM]":"45.9","Brain RNA - cerebral cortex [nTPM]":"62.0","Brain RNA - hippocampal formation [nTPM]":"39.2","Brain RNA - hypothalamus [nTPM]":"43.1","Brain RNA - medulla oblongata [nTPM]":"59.4","Brain RNA - midbrain [nTPM]":"54.4","Brain RNA - pons [nTPM]":"54.7","Brain RNA - spinal cord [nTPM]":"36.2","Brain RNA - thalamus [nTPM]":"55.9","Brain RNA - white matter [nTPM]":"104.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"118.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"81.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"1.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.4","Single Cell Type RNA - Bipolar cells [nTPM]":"1.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"106.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"47.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"171.6","Single Cell Type RNA - Club cells [nTPM]":"74.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"35.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"52.6","Single Cell Type RNA - dendritic cells [nTPM]":"2.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"254.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"60.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"36.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.9","Single Cell Type RNA - Endothelial cells [nTPM]":"2.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"93.1","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"88.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"84.6","Single Cell Type RNA - Fibroblasts [nTPM]":"4.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"96.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"95.9","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"112.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"145.2","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"3.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"1.5","Single Cell Type RNA - Melanocytes [nTPM]":"55.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"1.7","Single Cell Type RNA - Muller glia cells [nTPM]":"7.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"49.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"187.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"94.8","Single Cell Type RNA - Paneth cells [nTPM]":"184.6","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"103.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"240.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"30.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"54.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.4","Single Cell Type RNA - Spermatocytes [nTPM]":"9.5","Single Cell Type RNA - Spermatogonia [nTPM]":"13.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"87.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"36.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"100.6","Single Cell Type RNA - T-cells [nTPM]":"2.5","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"136.9","Single Cell Type RNA - Urothelial cells [nTPM]":"135.4"},{"Gene":"ERCC2","Gene synonym":["EM9","MAG","MGC102762","MGC126218","MGC126219","XPD"],"Ensembl":"ENSG00000104884","Gene description":"ERCC excision repair 2, TFIIH core complex helicase subunit","Uniprot":["P18074"],"Chromosome":"19","Position":"45349837-45370918","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Chromosome partition","DNA damage","DNA repair","Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Cancer-related genes","Cataract","Cockayne syndrome","Deafness","Disease variant","Dwarfism","Ichthyosis","Xeroderma pigmentosum"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"34.1","Spermatocytes":"30.5","Theca cells":"29.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005375","HPA038057","HPA069266"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB005375":"AB_2100152","HPA038057":"AB_2675810","HPA069266":"AB_2686104"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.26e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.8","Tissue RNA - adrenal gland [nTPM]":"13.0","Tissue RNA - amygdala [nTPM]":"10.5","Tissue RNA - appendix [nTPM]":"6.9","Tissue RNA - basal ganglia [nTPM]":"10.3","Tissue RNA - bone marrow [nTPM]":"4.8","Tissue RNA - breast [nTPM]":"6.5","Tissue RNA - cerebellum [nTPM]":"8.4","Tissue RNA - cerebral cortex [nTPM]":"11.7","Tissue RNA - cervix [nTPM]":"7.5","Tissue RNA - choroid plexus [nTPM]":"8.4","Tissue RNA - colon [nTPM]":"7.5","Tissue RNA - duodenum [nTPM]":"4.9","Tissue RNA - endometrium 1 [nTPM]":"9.7","Tissue RNA - epididymis [nTPM]":"3.2","Tissue RNA - esophagus [nTPM]":"6.3","Tissue RNA - fallopian tube [nTPM]":"8.0","Tissue RNA - gallbladder [nTPM]":"4.1","Tissue RNA - heart muscle [nTPM]":"7.0","Tissue RNA - hippocampal formation [nTPM]":"10.8","Tissue RNA - hypothalamus [nTPM]":"9.3","Tissue RNA - kidney [nTPM]":"7.6","Tissue RNA - liver [nTPM]":"9.0","Tissue RNA - lung [nTPM]":"5.8","Tissue RNA - lymph node [nTPM]":"5.8","Tissue RNA - medulla oblongata [nTPM]":"10.6","Tissue RNA - midbrain [nTPM]":"9.9","Tissue RNA - ovary [nTPM]":"7.8","Tissue RNA - pancreas [nTPM]":"7.7","Tissue RNA - parathyroid gland [nTPM]":"7.7","Tissue RNA - pituitary gland [nTPM]":"9.7","Tissue RNA - placenta [nTPM]":"4.5","Tissue RNA - pons [nTPM]":"9.6","Tissue RNA - prostate [nTPM]":"6.7","Tissue RNA - rectum [nTPM]":"4.0","Tissue RNA - retina [nTPM]":"3.1","Tissue RNA - salivary gland [nTPM]":"7.3","Tissue RNA - seminal vesicle [nTPM]":"6.7","Tissue RNA - skeletal muscle [nTPM]":"11.7","Tissue RNA - skin 1 [nTPM]":"7.2","Tissue RNA - small intestine [nTPM]":"6.6","Tissue RNA - smooth muscle [nTPM]":"6.9","Tissue RNA - spinal cord [nTPM]":"8.1","Tissue RNA - spleen [nTPM]":"8.1","Tissue RNA - stomach 1 [nTPM]":"7.5","Tissue RNA - testis [nTPM]":"13.9","Tissue RNA - thalamus [nTPM]":"10.1","Tissue RNA - thymus [nTPM]":"5.3","Tissue RNA - thyroid gland [nTPM]":"8.4","Tissue RNA - tongue [nTPM]":"6.3","Tissue RNA - tonsil [nTPM]":"5.2","Tissue RNA - urinary bladder [nTPM]":"7.5","Tissue RNA - vagina [nTPM]":"5.9","Tissue RNA - white matter [nTPM]":"8.9","Cell RNA - A-431 [nTPM]":"28.0","Cell RNA - A549 [nTPM]":"13.3","Cell RNA - AF22 [nTPM]":"27.1","Cell RNA - AN3-CA [nTPM]":"38.4","Cell RNA - ASC diff [nTPM]":"16.3","Cell RNA - ASC TERT1 [nTPM]":"19.4","Cell RNA - BEWO [nTPM]":"15.2","Cell RNA - BJ [nTPM]":"38.8","Cell RNA - BJ hTERT+ [nTPM]":"27.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"50.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"40.2","Cell RNA - CACO-2 [nTPM]":"32.6","Cell RNA - CAPAN-2 [nTPM]":"18.6","Cell RNA - Daudi [nTPM]":"10.0","Cell RNA - EFO-21 [nTPM]":"21.6","Cell RNA - fHDF\/TERT166 [nTPM]":"39.9","Cell RNA - GAMG [nTPM]":"19.1","Cell RNA - HaCaT [nTPM]":"14.0","Cell RNA - HAP1 [nTPM]":"19.1","Cell RNA - HBEC3-KT [nTPM]":"32.9","Cell RNA - HBF TERT88 [nTPM]":"18.5","Cell RNA - HDLM-2 [nTPM]":"24.4","Cell RNA - HEK 293 [nTPM]":"31.8","Cell RNA - HEL [nTPM]":"16.9","Cell RNA - HeLa [nTPM]":"26.8","Cell RNA - Hep G2 [nTPM]":"35.4","Cell RNA - HHSteC [nTPM]":"33.3","Cell RNA - HL-60 [nTPM]":"27.1","Cell RNA - HMC-1 [nTPM]":"28.4","Cell RNA - HSkMC [nTPM]":"22.4","Cell RNA - hTCEpi [nTPM]":"5.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"55.8","Cell RNA - hTERT-HME1 [nTPM]":"31.9","Cell RNA - hTERT-RPE1 [nTPM]":"28.2","Cell RNA - HUVEC TERT2 [nTPM]":"29.1","Cell RNA - JURKAT [nTPM]":"28.8","Cell RNA - K-562 [nTPM]":"41.8","Cell RNA - Karpas-707 [nTPM]":"10.9","Cell RNA - LHCN-M2 [nTPM]":"34.8","Cell RNA - MCF7 [nTPM]":"14.7","Cell RNA - MOLT-4 [nTPM]":"16.1","Cell RNA - NB-4 [nTPM]":"17.9","Cell RNA - NTERA-2 [nTPM]":"12.7","Cell RNA - OE19 [nTPM]":"27.2","Cell RNA - PC-3 [nTPM]":"24.6","Cell RNA - REH [nTPM]":"30.3","Cell RNA - RH-30 [nTPM]":"19.4","Cell RNA - RPMI-8226 [nTPM]":"8.3","Cell RNA - RPTEC TERT1 [nTPM]":"14.0","Cell RNA - RT4 [nTPM]":"24.9","Cell RNA - SCLC-21H [nTPM]":"15.8","Cell RNA - SH-SY5Y [nTPM]":"17.1","Cell RNA - SiHa [nTPM]":"34.2","Cell RNA - SK-BR-3 [nTPM]":"23.9","Cell RNA - SK-MEL-30 [nTPM]":"13.6","Cell RNA - SuSa [nTPM]":"20.6","Cell RNA - T-47d [nTPM]":"22.8","Cell RNA - THP-1 [nTPM]":"35.4","Cell RNA - TIME [nTPM]":"37.9","Cell RNA - U-138 MG [nTPM]":"46.4","Cell RNA - U-2 OS [nTPM]":"25.3","Cell RNA - U-2197 [nTPM]":"19.9","Cell RNA - U-251 MG [nTPM]":"88.0","Cell RNA - U-266\/70 [nTPM]":"24.9","Cell RNA - U-266\/84 [nTPM]":"15.8","Cell RNA - U-698 [nTPM]":"14.2","Cell RNA - U-87 MG [nTPM]":"13.8","Cell RNA - U-937 [nTPM]":"16.4","Cell RNA - WM-115 [nTPM]":"21.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"17.2","Blood RNA - eosinophil [nTPM]":"6.5","Blood RNA - gdT-cell [nTPM]":"9.1","Blood RNA - intermediate monocyte [nTPM]":"18.0","Blood RNA - MAIT T-cell [nTPM]":"11.9","Blood RNA - memory B-cell [nTPM]":"9.1","Blood RNA - memory CD4 T-cell [nTPM]":"8.9","Blood RNA - memory CD8 T-cell [nTPM]":"8.9","Blood RNA - myeloid DC [nTPM]":"21.8","Blood RNA - naive B-cell [nTPM]":"6.5","Blood RNA - naive CD4 T-cell [nTPM]":"8.2","Blood RNA - naive CD8 T-cell [nTPM]":"8.7","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"15.6","Blood RNA - non-classical monocyte [nTPM]":"14.9","Blood RNA - plasmacytoid DC [nTPM]":"10.4","Blood RNA - T-reg [nTPM]":"9.8","Blood RNA - total PBMC [nTPM]":"12.1","Brain RNA - amygdala [nTPM]":"10.5","Brain RNA - basal ganglia [nTPM]":"10.3","Brain RNA - cerebellum [nTPM]":"8.4","Brain RNA - cerebral cortex [nTPM]":"11.7","Brain RNA - hippocampal formation [nTPM]":"10.8","Brain RNA - hypothalamus [nTPM]":"9.3","Brain RNA - medulla oblongata [nTPM]":"10.6","Brain RNA - midbrain [nTPM]":"9.9","Brain RNA - pons [nTPM]":"9.6","Brain RNA - spinal cord [nTPM]":"8.1","Brain RNA - thalamus [nTPM]":"10.1","Brain RNA - white matter [nTPM]":"8.9","Single Cell Type RNA - Adipocytes [nTPM]":"4.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.4","Single Cell Type RNA - Astrocytes [nTPM]":"6.2","Single Cell Type RNA - B-cells [nTPM]":"5.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"8.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.5","Single Cell Type RNA - dendritic cells [nTPM]":"4.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"10.7","Single Cell Type RNA - Early spermatids [nTPM]":"4.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.5","Single Cell Type RNA - Endothelial cells [nTPM]":"5.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"5.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.1","Single Cell Type RNA - Fibroblasts [nTPM]":"6.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"34.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"12.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.5","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"8.2","Single Cell Type RNA - Langerhans cells [nTPM]":"4.2","Single Cell Type RNA - Late spermatids [nTPM]":"2.8","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"6.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"4.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.1","Single Cell Type RNA - Paneth cells [nTPM]":"3.1","Single Cell Type RNA - Peritubular cells [nTPM]":"7.9","Single Cell Type RNA - Plasma cells [nTPM]":"7.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.9","Single Cell Type RNA - Spermatocytes [nTPM]":"30.5","Single Cell Type RNA - Spermatogonia [nTPM]":"13.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.8","Single Cell Type RNA - T-cells [nTPM]":"4.7","Single Cell Type RNA - Theca cells [nTPM]":"29.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.8","Single Cell Type RNA - Urothelial cells [nTPM]":"3.2"},{"Gene":"ERCC3","Gene synonym":["BTF2","RAD25","XPB"],"Ensembl":"ENSG00000163161","Gene description":"ERCC excision repair 3, TFIIH core complex helicase subunit","Uniprot":["P19447"],"Chromosome":"2","Position":"127257290-127294166","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Cancer-related genes","Cockayne syndrome","Deafness","Disease variant","Dwarfism","Ichthyosis","Xeroderma pigmentosum"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037153","HPA046077"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB037153":"AB_796181","HPA046077":"AB_2679527"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.62e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.30e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Tissue RNA - adipose tissue [nTPM]":"24.4","Tissue RNA - adrenal gland [nTPM]":"25.9","Tissue RNA - amygdala [nTPM]":"15.0","Tissue RNA - appendix [nTPM]":"14.5","Tissue RNA - basal ganglia [nTPM]":"16.0","Tissue RNA - bone marrow [nTPM]":"19.8","Tissue RNA - breast [nTPM]":"24.4","Tissue RNA - cerebellum [nTPM]":"15.1","Tissue RNA - cerebral cortex [nTPM]":"16.5","Tissue RNA - cervix [nTPM]":"32.2","Tissue RNA - choroid plexus [nTPM]":"19.6","Tissue RNA - colon [nTPM]":"28.9","Tissue RNA - duodenum [nTPM]":"9.6","Tissue RNA - endometrium 1 [nTPM]":"27.0","Tissue RNA - epididymis [nTPM]":"11.6","Tissue RNA - esophagus [nTPM]":"22.7","Tissue RNA - fallopian tube [nTPM]":"28.9","Tissue RNA - gallbladder [nTPM]":"14.2","Tissue RNA - heart muscle [nTPM]":"23.4","Tissue RNA - hippocampal formation [nTPM]":"16.6","Tissue RNA - hypothalamus [nTPM]":"14.9","Tissue RNA - kidney [nTPM]":"22.8","Tissue RNA - liver [nTPM]":"22.2","Tissue RNA - lung [nTPM]":"22.1","Tissue RNA - lymph node [nTPM]":"21.6","Tissue RNA - medulla oblongata [nTPM]":"15.7","Tissue RNA - midbrain [nTPM]":"14.8","Tissue RNA - ovary [nTPM]":"29.5","Tissue RNA - pancreas [nTPM]":"23.8","Tissue RNA - parathyroid gland [nTPM]":"26.3","Tissue RNA - pituitary gland [nTPM]":"33.8","Tissue RNA - placenta [nTPM]":"13.6","Tissue RNA - pons [nTPM]":"16.0","Tissue RNA - prostate [nTPM]":"27.4","Tissue RNA - rectum [nTPM]":"13.8","Tissue RNA - retina [nTPM]":"4.4","Tissue RNA - salivary gland [nTPM]":"23.2","Tissue RNA - seminal vesicle [nTPM]":"16.8","Tissue RNA - skeletal muscle [nTPM]":"35.3","Tissue RNA - skin 1 [nTPM]":"27.7","Tissue RNA - small intestine [nTPM]":"24.3","Tissue RNA - smooth muscle [nTPM]":"21.5","Tissue RNA - spinal cord [nTPM]":"15.1","Tissue RNA - spleen [nTPM]":"32.6","Tissue RNA - stomach 1 [nTPM]":"23.7","Tissue RNA - testis [nTPM]":"29.8","Tissue RNA - thalamus [nTPM]":"15.6","Tissue RNA - thymus [nTPM]":"26.6","Tissue RNA - thyroid gland [nTPM]":"25.0","Tissue RNA - tongue [nTPM]":"25.6","Tissue RNA - tonsil [nTPM]":"22.4","Tissue RNA - urinary bladder [nTPM]":"27.2","Tissue RNA - vagina [nTPM]":"26.4","Tissue RNA - white matter [nTPM]":"15.2","Cell RNA - A-431 [nTPM]":"45.9","Cell RNA - A549 [nTPM]":"30.8","Cell RNA - AF22 [nTPM]":"37.8","Cell RNA - AN3-CA [nTPM]":"40.6","Cell RNA - ASC diff [nTPM]":"40.6","Cell RNA - ASC TERT1 [nTPM]":"27.8","Cell RNA - BEWO [nTPM]":"46.4","Cell RNA - BJ [nTPM]":"41.3","Cell RNA - BJ hTERT+ [nTPM]":"52.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"65.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"62.5","Cell RNA - CACO-2 [nTPM]":"48.1","Cell RNA - CAPAN-2 [nTPM]":"32.9","Cell RNA - Daudi [nTPM]":"34.5","Cell RNA - EFO-21 [nTPM]":"33.2","Cell RNA - fHDF\/TERT166 [nTPM]":"37.8","Cell RNA - GAMG [nTPM]":"41.7","Cell RNA - HaCaT [nTPM]":"40.2","Cell RNA - HAP1 [nTPM]":"57.7","Cell RNA - HBEC3-KT [nTPM]":"43.3","Cell RNA - HBF TERT88 [nTPM]":"56.1","Cell RNA - HDLM-2 [nTPM]":"54.4","Cell RNA - HEK 293 [nTPM]":"51.4","Cell RNA - HEL [nTPM]":"43.6","Cell RNA - HeLa [nTPM]":"35.8","Cell RNA - Hep G2 [nTPM]":"51.0","Cell RNA - HHSteC [nTPM]":"30.5","Cell RNA - HL-60 [nTPM]":"38.1","Cell RNA - HMC-1 [nTPM]":"45.4","Cell RNA - HSkMC [nTPM]":"28.9","Cell RNA - hTCEpi [nTPM]":"39.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"75.7","Cell RNA - hTERT-HME1 [nTPM]":"32.4","Cell RNA - hTERT-RPE1 [nTPM]":"41.5","Cell RNA - HUVEC TERT2 [nTPM]":"42.4","Cell RNA - JURKAT [nTPM]":"44.3","Cell RNA - K-562 [nTPM]":"43.0","Cell RNA - Karpas-707 [nTPM]":"22.1","Cell RNA - LHCN-M2 [nTPM]":"41.7","Cell RNA - MCF7 [nTPM]":"45.1","Cell RNA - MOLT-4 [nTPM]":"54.8","Cell RNA - NB-4 [nTPM]":"42.2","Cell RNA - NTERA-2 [nTPM]":"55.0","Cell RNA - OE19 [nTPM]":"29.2","Cell RNA - PC-3 [nTPM]":"47.3","Cell RNA - REH [nTPM]":"44.5","Cell RNA - RH-30 [nTPM]":"42.7","Cell RNA - RPMI-8226 [nTPM]":"28.8","Cell RNA - RPTEC TERT1 [nTPM]":"36.4","Cell RNA - RT4 [nTPM]":"42.2","Cell RNA - SCLC-21H [nTPM]":"45.2","Cell RNA - SH-SY5Y [nTPM]":"49.2","Cell RNA - SiHa [nTPM]":"35.3","Cell RNA - SK-BR-3 [nTPM]":"52.6","Cell RNA - SK-MEL-30 [nTPM]":"55.0","Cell RNA - SuSa [nTPM]":"42.4","Cell RNA - T-47d [nTPM]":"28.7","Cell RNA - THP-1 [nTPM]":"43.0","Cell RNA - TIME [nTPM]":"34.1","Cell RNA - U-138 MG [nTPM]":"39.2","Cell RNA - U-2 OS [nTPM]":"45.2","Cell RNA - U-2197 [nTPM]":"35.8","Cell RNA - U-251 MG [nTPM]":"49.7","Cell RNA - U-266\/70 [nTPM]":"39.2","Cell RNA - U-266\/84 [nTPM]":"81.5","Cell RNA - U-698 [nTPM]":"54.0","Cell RNA - U-87 MG [nTPM]":"34.3","Cell RNA - U-937 [nTPM]":"18.0","Cell RNA - WM-115 [nTPM]":"42.8","Blood RNA - basophil [nTPM]":"8.0","Blood RNA - classical monocyte [nTPM]":"11.5","Blood RNA - eosinophil [nTPM]":"8.8","Blood RNA - gdT-cell [nTPM]":"18.2","Blood RNA - intermediate monocyte [nTPM]":"12.0","Blood RNA - MAIT T-cell [nTPM]":"18.4","Blood RNA - memory B-cell [nTPM]":"13.7","Blood RNA - memory CD4 T-cell [nTPM]":"13.1","Blood RNA - memory CD8 T-cell [nTPM]":"15.7","Blood RNA - myeloid DC [nTPM]":"16.9","Blood RNA - naive B-cell [nTPM]":"12.7","Blood RNA - naive CD4 T-cell [nTPM]":"17.7","Blood RNA - naive CD8 T-cell [nTPM]":"12.2","Blood RNA - neutrophil [nTPM]":"3.5","Blood RNA - NK-cell [nTPM]":"25.0","Blood RNA - non-classical monocyte [nTPM]":"9.9","Blood RNA - plasmacytoid DC [nTPM]":"13.6","Blood RNA - T-reg [nTPM]":"20.5","Blood RNA - total PBMC [nTPM]":"15.5","Brain RNA - amygdala [nTPM]":"15.0","Brain RNA - basal ganglia [nTPM]":"16.0","Brain RNA - cerebellum [nTPM]":"15.1","Brain RNA - cerebral cortex [nTPM]":"16.5","Brain RNA - hippocampal formation [nTPM]":"16.6","Brain RNA - hypothalamus [nTPM]":"14.9","Brain RNA - medulla oblongata [nTPM]":"15.7","Brain RNA - midbrain [nTPM]":"14.8","Brain RNA - pons [nTPM]":"16.0","Brain RNA - spinal cord [nTPM]":"15.1","Brain RNA - thalamus [nTPM]":"15.6","Brain RNA - white matter [nTPM]":"15.2","Single Cell Type RNA - Adipocytes [nTPM]":"12.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.6","Single Cell Type RNA - Astrocytes [nTPM]":"24.8","Single Cell Type RNA - B-cells [nTPM]":"17.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"20.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.1","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"25.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.6","Single Cell Type RNA - dendritic cells [nTPM]":"18.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"13.7","Single Cell Type RNA - Early spermatids [nTPM]":"9.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.9","Single Cell Type RNA - Endothelial cells [nTPM]":"12.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.1","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.2","Single Cell Type RNA - Fibroblasts [nTPM]":"16.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.1","Single Cell Type RNA - granulocytes [nTPM]":"10.1","Single Cell Type RNA - Granulosa cells [nTPM]":"17.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.4","Single Cell Type RNA - Hepatocytes [nTPM]":"8.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"23.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.0","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"12.5","Single Cell Type RNA - Langerhans cells [nTPM]":"7.6","Single Cell Type RNA - Late spermatids [nTPM]":"5.1","Single Cell Type RNA - Leydig cells [nTPM]":"16.4","Single Cell Type RNA - Macrophages [nTPM]":"10.7","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"12.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"22.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.5","Single Cell Type RNA - Paneth cells [nTPM]":"7.3","Single Cell Type RNA - Peritubular cells [nTPM]":"12.8","Single Cell Type RNA - Plasma cells [nTPM]":"16.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"45.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.3","Single Cell Type RNA - Spermatocytes [nTPM]":"41.1","Single Cell Type RNA - Spermatogonia [nTPM]":"31.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.6","Single Cell Type RNA - T-cells [nTPM]":"15.7","Single Cell Type RNA - Theca cells [nTPM]":"12.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.6","Single Cell Type RNA - Urothelial cells [nTPM]":"8.5"},{"Gene":"ERLIN1","Gene synonym":["C10orf69","Erlin-1","KE04","SPFH1","SPG62"],"Ensembl":"ENSG00000107566","Gene description":"ER lipid raft associated 1","Uniprot":["O75477"],"Chromosome":"10","Position":"100150094-100186033","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Steroid metabolism","Sterol metabolism"],"Molecular function":null,"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"114.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"77.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011252"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA011252":"AB_1853965"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.63e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Tissue RNA - adipose tissue [nTPM]":"29.4","Tissue RNA - adrenal gland [nTPM]":"14.2","Tissue RNA - amygdala [nTPM]":"8.6","Tissue RNA - appendix [nTPM]":"21.4","Tissue RNA - basal ganglia [nTPM]":"10.5","Tissue RNA - bone marrow [nTPM]":"76.2","Tissue RNA - breast [nTPM]":"21.4","Tissue RNA - cerebellum [nTPM]":"9.5","Tissue RNA - cerebral cortex [nTPM]":"10.1","Tissue RNA - cervix [nTPM]":"27.5","Tissue RNA - choroid plexus [nTPM]":"10.3","Tissue RNA - colon [nTPM]":"37.0","Tissue RNA - duodenum [nTPM]":"40.4","Tissue RNA - endometrium 1 [nTPM]":"21.8","Tissue RNA - epididymis [nTPM]":"17.6","Tissue RNA - esophagus [nTPM]":"32.8","Tissue RNA - fallopian tube [nTPM]":"31.6","Tissue RNA - gallbladder [nTPM]":"16.3","Tissue RNA - heart muscle [nTPM]":"11.0","Tissue RNA - hippocampal formation [nTPM]":"9.6","Tissue RNA - hypothalamus [nTPM]":"9.4","Tissue RNA - kidney [nTPM]":"27.2","Tissue RNA - liver [nTPM]":"114.1","Tissue RNA - lung [nTPM]":"19.1","Tissue RNA - lymph node [nTPM]":"14.5","Tissue RNA - medulla oblongata [nTPM]":"8.6","Tissue RNA - midbrain [nTPM]":"8.2","Tissue RNA - ovary [nTPM]":"30.4","Tissue RNA - pancreas [nTPM]":"19.2","Tissue RNA - parathyroid gland [nTPM]":"19.4","Tissue RNA - pituitary gland [nTPM]":"5.4","Tissue RNA - placenta [nTPM]":"42.2","Tissue RNA - pons [nTPM]":"9.0","Tissue RNA - prostate [nTPM]":"17.7","Tissue RNA - rectum [nTPM]":"38.2","Tissue RNA - retina [nTPM]":"10.8","Tissue RNA - salivary gland [nTPM]":"15.1","Tissue RNA - seminal vesicle [nTPM]":"16.4","Tissue RNA - skeletal muscle [nTPM]":"8.6","Tissue RNA - skin 1 [nTPM]":"22.5","Tissue RNA - small intestine [nTPM]":"30.2","Tissue RNA - smooth muscle [nTPM]":"22.4","Tissue RNA - spinal cord [nTPM]":"8.8","Tissue RNA - spleen [nTPM]":"16.6","Tissue RNA - stomach 1 [nTPM]":"36.8","Tissue RNA - testis [nTPM]":"28.0","Tissue RNA - thalamus [nTPM]":"9.0","Tissue RNA - thymus [nTPM]":"15.6","Tissue RNA - thyroid gland [nTPM]":"26.2","Tissue RNA - tongue [nTPM]":"13.6","Tissue RNA - tonsil [nTPM]":"21.2","Tissue RNA - urinary bladder [nTPM]":"28.6","Tissue RNA - vagina [nTPM]":"19.1","Tissue RNA - white matter [nTPM]":"9.7","Cell RNA - A-431 [nTPM]":"97.4","Cell RNA - A549 [nTPM]":"95.3","Cell RNA - AF22 [nTPM]":"46.9","Cell RNA - AN3-CA [nTPM]":"86.3","Cell RNA - ASC diff [nTPM]":"113.5","Cell RNA - ASC TERT1 [nTPM]":"107.9","Cell RNA - BEWO [nTPM]":"96.8","Cell RNA - BJ [nTPM]":"148.7","Cell RNA - BJ hTERT+ [nTPM]":"138.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"120.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"137.5","Cell RNA - CACO-2 [nTPM]":"64.0","Cell RNA - CAPAN-2 [nTPM]":"109.9","Cell RNA - Daudi [nTPM]":"42.6","Cell RNA - EFO-21 [nTPM]":"59.7","Cell RNA - fHDF\/TERT166 [nTPM]":"139.9","Cell RNA - GAMG [nTPM]":"100.5","Cell RNA - HaCaT [nTPM]":"98.5","Cell RNA - HAP1 [nTPM]":"42.6","Cell RNA - HBEC3-KT [nTPM]":"90.0","Cell RNA - HBF TERT88 [nTPM]":"164.1","Cell RNA - HDLM-2 [nTPM]":"26.1","Cell RNA - HEK 293 [nTPM]":"38.8","Cell RNA - HEL [nTPM]":"36.7","Cell RNA - HeLa [nTPM]":"38.5","Cell RNA - Hep G2 [nTPM]":"83.5","Cell RNA - HHSteC [nTPM]":"47.6","Cell RNA - HL-60 [nTPM]":"128.4","Cell RNA - HMC-1 [nTPM]":"39.4","Cell RNA - HSkMC [nTPM]":"62.6","Cell RNA - hTCEpi [nTPM]":"53.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"105.8","Cell RNA - hTERT-HME1 [nTPM]":"129.2","Cell RNA - hTERT-RPE1 [nTPM]":"114.9","Cell RNA - HUVEC TERT2 [nTPM]":"90.1","Cell RNA - JURKAT [nTPM]":"43.5","Cell RNA - K-562 [nTPM]":"36.8","Cell RNA - Karpas-707 [nTPM]":"25.2","Cell RNA - LHCN-M2 [nTPM]":"130.2","Cell RNA - MCF7 [nTPM]":"40.7","Cell RNA - MOLT-4 [nTPM]":"33.5","Cell RNA - NB-4 [nTPM]":"65.9","Cell RNA - NTERA-2 [nTPM]":"33.8","Cell RNA - OE19 [nTPM]":"66.2","Cell RNA - PC-3 [nTPM]":"40.4","Cell RNA - REH [nTPM]":"28.3","Cell RNA - RH-30 [nTPM]":"77.2","Cell RNA - RPMI-8226 [nTPM]":"31.6","Cell RNA - RPTEC TERT1 [nTPM]":"53.9","Cell RNA - RT4 [nTPM]":"37.6","Cell RNA - SCLC-21H [nTPM]":"19.1","Cell RNA - SH-SY5Y [nTPM]":"31.1","Cell RNA - SiHa [nTPM]":"85.6","Cell RNA - SK-BR-3 [nTPM]":"23.6","Cell RNA - SK-MEL-30 [nTPM]":"56.0","Cell RNA - SuSa [nTPM]":"53.8","Cell RNA - T-47d [nTPM]":"59.3","Cell RNA - THP-1 [nTPM]":"109.0","Cell RNA - TIME [nTPM]":"101.7","Cell RNA - U-138 MG [nTPM]":"118.7","Cell RNA - U-2 OS [nTPM]":"92.4","Cell RNA - U-2197 [nTPM]":"72.4","Cell RNA - U-251 MG [nTPM]":"160.8","Cell RNA - U-266\/70 [nTPM]":"19.6","Cell RNA - U-266\/84 [nTPM]":"35.2","Cell RNA - U-698 [nTPM]":"57.1","Cell RNA - U-87 MG [nTPM]":"105.6","Cell RNA - U-937 [nTPM]":"204.8","Cell RNA - WM-115 [nTPM]":"60.6","Blood RNA - basophil [nTPM]":"8.1","Blood RNA - classical monocyte [nTPM]":"20.4","Blood RNA - eosinophil [nTPM]":"24.4","Blood RNA - gdT-cell [nTPM]":"10.5","Blood RNA - intermediate monocyte [nTPM]":"15.1","Blood RNA - MAIT T-cell [nTPM]":"9.3","Blood RNA - memory B-cell [nTPM]":"7.4","Blood RNA - memory CD4 T-cell [nTPM]":"7.9","Blood RNA - memory CD8 T-cell [nTPM]":"8.6","Blood RNA - myeloid DC [nTPM]":"16.3","Blood RNA - naive B-cell [nTPM]":"6.7","Blood RNA - naive CD4 T-cell [nTPM]":"8.1","Blood RNA - naive CD8 T-cell [nTPM]":"10.9","Blood RNA - neutrophil [nTPM]":"15.0","Blood RNA - NK-cell [nTPM]":"9.9","Blood RNA - non-classical monocyte [nTPM]":"11.9","Blood RNA - plasmacytoid DC [nTPM]":"4.1","Blood RNA - T-reg [nTPM]":"5.6","Blood RNA - total PBMC [nTPM]":"9.7","Brain RNA - amygdala [nTPM]":"8.6","Brain RNA - basal ganglia [nTPM]":"10.5","Brain RNA - cerebellum [nTPM]":"9.5","Brain RNA - cerebral cortex [nTPM]":"10.1","Brain RNA - hippocampal formation [nTPM]":"9.6","Brain RNA - hypothalamus [nTPM]":"9.4","Brain RNA - medulla oblongata [nTPM]":"8.6","Brain RNA - midbrain [nTPM]":"8.2","Brain RNA - pons [nTPM]":"9.0","Brain RNA - spinal cord [nTPM]":"8.8","Brain RNA - thalamus [nTPM]":"9.0","Brain RNA - white matter [nTPM]":"9.7","Single Cell Type RNA - Adipocytes [nTPM]":"28.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.5","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"6.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Bipolar cells [nTPM]":"4.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"14.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.6","Single Cell Type RNA - dendritic cells [nTPM]":"6.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"31.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"9.9","Single Cell Type RNA - Early spermatids [nTPM]":"28.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.5","Single Cell Type RNA - Endothelial cells [nTPM]":"18.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.2","Single Cell Type RNA - Erythroid cells [nTPM]":"19.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"62.7","Single Cell Type RNA - Fibroblasts [nTPM]":"17.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.9","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"19.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"77.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.3","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"27.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"14.4","Single Cell Type RNA - Langerhans cells [nTPM]":"7.2","Single Cell Type RNA - Late spermatids [nTPM]":"12.9","Single Cell Type RNA - Leydig cells [nTPM]":"15.2","Single Cell Type RNA - Macrophages [nTPM]":"12.9","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"13.3","Single Cell Type RNA - Muller glia cells [nTPM]":"5.9","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.5","Single Cell Type RNA - Paneth cells [nTPM]":"19.8","Single Cell Type RNA - Peritubular cells [nTPM]":"7.9","Single Cell Type RNA - Plasma cells [nTPM]":"4.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"25.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"30.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.8","Single Cell Type RNA - Spermatocytes [nTPM]":"50.9","Single Cell Type RNA - Spermatogonia [nTPM]":"15.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"24.8","Single Cell Type RNA - T-cells [nTPM]":"6.6","Single Cell Type RNA - Theca cells [nTPM]":"19.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"27.6","Single Cell Type RNA - Urothelial cells [nTPM]":"15.6"},{"Gene":"ERLIN2","Gene synonym":["C8orf2","Erlin-2","NET32","SPFH2","SPG18"],"Ensembl":"ENSG00000147475","Gene description":"ER lipid raft associated 2","Uniprot":["O94905"],"Chromosome":"8","Position":"37736601-37758422","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Steroid metabolism","Sterol metabolism"],"Molecular function":null,"Disease involvement":["Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002025","CAB014894"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB014894":null,"HPA002025":"AB_1080077"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.16e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.51e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.67e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Tissue RNA - adipose tissue [nTPM]":"20.3","Tissue RNA - adrenal gland [nTPM]":"17.8","Tissue RNA - amygdala [nTPM]":"15.7","Tissue RNA - appendix [nTPM]":"14.6","Tissue RNA - basal ganglia [nTPM]":"17.3","Tissue RNA - bone marrow [nTPM]":"14.4","Tissue RNA - breast [nTPM]":"25.0","Tissue RNA - cerebellum [nTPM]":"16.5","Tissue RNA - cerebral cortex [nTPM]":"16.8","Tissue RNA - cervix [nTPM]":"20.0","Tissue RNA - choroid plexus [nTPM]":"27.2","Tissue RNA - colon [nTPM]":"24.2","Tissue RNA - duodenum [nTPM]":"17.7","Tissue RNA - endometrium 1 [nTPM]":"21.2","Tissue RNA - epididymis [nTPM]":"32.3","Tissue RNA - esophagus [nTPM]":"17.9","Tissue RNA - fallopian tube [nTPM]":"30.1","Tissue RNA - gallbladder [nTPM]":"19.8","Tissue RNA - heart muscle [nTPM]":"17.8","Tissue RNA - hippocampal formation [nTPM]":"14.2","Tissue RNA - hypothalamus [nTPM]":"16.3","Tissue RNA - kidney [nTPM]":"40.4","Tissue RNA - liver [nTPM]":"40.8","Tissue RNA - lung [nTPM]":"15.5","Tissue RNA - lymph node [nTPM]":"11.5","Tissue RNA - medulla oblongata [nTPM]":"18.0","Tissue RNA - midbrain [nTPM]":"18.5","Tissue RNA - ovary [nTPM]":"30.8","Tissue RNA - pancreas [nTPM]":"26.2","Tissue RNA - parathyroid gland [nTPM]":"41.4","Tissue RNA - pituitary gland [nTPM]":"8.3","Tissue RNA - placenta [nTPM]":"21.2","Tissue RNA - pons [nTPM]":"17.7","Tissue RNA - prostate [nTPM]":"25.4","Tissue RNA - rectum [nTPM]":"25.0","Tissue RNA - retina [nTPM]":"21.6","Tissue RNA - salivary gland [nTPM]":"29.4","Tissue RNA - seminal vesicle [nTPM]":"23.8","Tissue RNA - skeletal muscle [nTPM]":"18.9","Tissue RNA - skin 1 [nTPM]":"15.3","Tissue RNA - small intestine [nTPM]":"23.6","Tissue RNA - smooth muscle [nTPM]":"19.5","Tissue RNA - spinal cord [nTPM]":"17.9","Tissue RNA - spleen [nTPM]":"14.6","Tissue RNA - stomach 1 [nTPM]":"24.9","Tissue RNA - testis [nTPM]":"17.0","Tissue RNA - thalamus [nTPM]":"15.6","Tissue RNA - thymus [nTPM]":"14.7","Tissue RNA - thyroid gland [nTPM]":"46.5","Tissue RNA - tongue [nTPM]":"14.1","Tissue RNA - tonsil [nTPM]":"12.6","Tissue RNA - urinary bladder [nTPM]":"16.8","Tissue RNA - vagina [nTPM]":"10.3","Tissue RNA - white matter [nTPM]":"18.6","Cell RNA - A-431 [nTPM]":"39.0","Cell RNA - A549 [nTPM]":"38.5","Cell RNA - AF22 [nTPM]":"43.0","Cell RNA - AN3-CA [nTPM]":"31.4","Cell RNA - ASC diff [nTPM]":"47.3","Cell RNA - ASC TERT1 [nTPM]":"33.9","Cell RNA - BEWO [nTPM]":"47.2","Cell RNA - BJ [nTPM]":"59.1","Cell RNA - BJ hTERT+ [nTPM]":"51.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"31.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"33.2","Cell RNA - CACO-2 [nTPM]":"20.1","Cell RNA - CAPAN-2 [nTPM]":"50.8","Cell RNA - Daudi [nTPM]":"18.9","Cell RNA - EFO-21 [nTPM]":"95.8","Cell RNA - fHDF\/TERT166 [nTPM]":"63.4","Cell RNA - GAMG [nTPM]":"30.3","Cell RNA - HaCaT [nTPM]":"41.4","Cell RNA - HAP1 [nTPM]":"31.2","Cell RNA - HBEC3-KT [nTPM]":"48.4","Cell RNA - HBF TERT88 [nTPM]":"46.8","Cell RNA - HDLM-2 [nTPM]":"11.2","Cell RNA - HEK 293 [nTPM]":"24.2","Cell RNA - HEL [nTPM]":"27.8","Cell RNA - HeLa [nTPM]":"22.7","Cell RNA - Hep G2 [nTPM]":"22.7","Cell RNA - HHSteC [nTPM]":"31.5","Cell RNA - HL-60 [nTPM]":"17.8","Cell RNA - HMC-1 [nTPM]":"34.1","Cell RNA - HSkMC [nTPM]":"43.3","Cell RNA - hTCEpi [nTPM]":"49.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"46.3","Cell RNA - hTERT-HME1 [nTPM]":"48.1","Cell RNA - hTERT-RPE1 [nTPM]":"39.6","Cell RNA - HUVEC TERT2 [nTPM]":"30.7","Cell RNA - JURKAT [nTPM]":"17.2","Cell RNA - K-562 [nTPM]":"51.1","Cell RNA - Karpas-707 [nTPM]":"17.7","Cell RNA - LHCN-M2 [nTPM]":"47.4","Cell RNA - MCF7 [nTPM]":"18.3","Cell RNA - MOLT-4 [nTPM]":"25.8","Cell RNA - NB-4 [nTPM]":"14.7","Cell RNA - NTERA-2 [nTPM]":"45.9","Cell RNA - OE19 [nTPM]":"53.8","Cell RNA - PC-3 [nTPM]":"17.7","Cell RNA - REH [nTPM]":"17.9","Cell RNA - RH-30 [nTPM]":"29.9","Cell RNA - RPMI-8226 [nTPM]":"15.2","Cell RNA - RPTEC TERT1 [nTPM]":"42.8","Cell RNA - RT4 [nTPM]":"41.9","Cell RNA - SCLC-21H [nTPM]":"7.7","Cell RNA - SH-SY5Y [nTPM]":"20.7","Cell RNA - SiHa [nTPM]":"39.3","Cell RNA - SK-BR-3 [nTPM]":"12.6","Cell RNA - SK-MEL-30 [nTPM]":"35.6","Cell RNA - SuSa [nTPM]":"50.1","Cell RNA - T-47d [nTPM]":"62.0","Cell RNA - THP-1 [nTPM]":"27.1","Cell RNA - TIME [nTPM]":"31.1","Cell RNA - U-138 MG [nTPM]":"30.9","Cell RNA - U-2 OS [nTPM]":"26.4","Cell RNA - U-2197 [nTPM]":"56.8","Cell RNA - U-251 MG [nTPM]":"31.1","Cell RNA - U-266\/70 [nTPM]":"24.3","Cell RNA - U-266\/84 [nTPM]":"41.0","Cell RNA - U-698 [nTPM]":"24.2","Cell RNA - U-87 MG [nTPM]":"55.0","Cell RNA - U-937 [nTPM]":"28.4","Cell RNA - WM-115 [nTPM]":"40.7","Blood RNA - basophil [nTPM]":"1.3","Blood RNA - classical monocyte [nTPM]":"6.5","Blood RNA - eosinophil [nTPM]":"13.4","Blood RNA - gdT-cell [nTPM]":"4.4","Blood RNA - intermediate monocyte [nTPM]":"7.0","Blood RNA - MAIT T-cell [nTPM]":"3.6","Blood RNA - memory B-cell [nTPM]":"4.5","Blood RNA - memory CD4 T-cell [nTPM]":"2.7","Blood RNA - memory CD8 T-cell [nTPM]":"3.5","Blood RNA - myeloid DC [nTPM]":"5.4","Blood RNA - naive B-cell [nTPM]":"2.3","Blood RNA - naive CD4 T-cell [nTPM]":"4.1","Blood RNA - naive CD8 T-cell [nTPM]":"3.8","Blood RNA - neutrophil [nTPM]":"6.1","Blood RNA - NK-cell [nTPM]":"2.5","Blood RNA - non-classical monocyte [nTPM]":"9.6","Blood RNA - plasmacytoid DC [nTPM]":"7.6","Blood RNA - T-reg [nTPM]":"5.5","Blood RNA - total PBMC [nTPM]":"3.1","Brain RNA - amygdala [nTPM]":"15.7","Brain RNA - basal ganglia [nTPM]":"17.3","Brain RNA - cerebellum [nTPM]":"16.5","Brain RNA - cerebral cortex [nTPM]":"16.8","Brain RNA - hippocampal formation [nTPM]":"14.2","Brain RNA - hypothalamus [nTPM]":"16.3","Brain RNA - medulla oblongata [nTPM]":"18.0","Brain RNA - midbrain [nTPM]":"18.5","Brain RNA - pons [nTPM]":"17.7","Brain RNA - spinal cord [nTPM]":"17.9","Brain RNA - thalamus [nTPM]":"15.6","Brain RNA - white matter [nTPM]":"18.6","Single Cell Type RNA - Adipocytes [nTPM]":"14.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.3","Single Cell Type RNA - Astrocytes [nTPM]":"21.5","Single Cell Type RNA - B-cells [nTPM]":"7.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Bipolar cells [nTPM]":"25.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"24.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"30.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"22.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"17.9","Single Cell Type RNA - dendritic cells [nTPM]":"6.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"19.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"23.8","Single Cell Type RNA - Early spermatids [nTPM]":"21.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"31.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.5","Single Cell Type RNA - Endothelial cells [nTPM]":"13.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.4","Single Cell Type RNA - Erythroid cells [nTPM]":"8.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"22.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"27.0","Single Cell Type RNA - Fibroblasts [nTPM]":"18.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"27.8","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"14.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.5","Single Cell Type RNA - Hepatocytes [nTPM]":"41.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.6","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.3","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"23.9","Single Cell Type RNA - Langerhans cells [nTPM]":"6.6","Single Cell Type RNA - Late spermatids [nTPM]":"16.8","Single Cell Type RNA - Leydig cells [nTPM]":"11.8","Single Cell Type RNA - Macrophages [nTPM]":"16.1","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"12.3","Single Cell Type RNA - Muller glia cells [nTPM]":"23.5","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.8","Single Cell Type RNA - Paneth cells [nTPM]":"17.4","Single Cell Type RNA - Peritubular cells [nTPM]":"17.7","Single Cell Type RNA - Plasma cells [nTPM]":"16.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"25.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"47.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.7","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.8","Single Cell Type RNA - Spermatocytes [nTPM]":"47.4","Single Cell Type RNA - Spermatogonia [nTPM]":"18.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.7","Single Cell Type RNA - T-cells [nTPM]":"7.1","Single Cell Type RNA - Theca cells [nTPM]":"12.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"25.4","Single Cell Type RNA - Urothelial cells [nTPM]":"12.8"},{"Gene":"ETHE1","Gene synonym":["HSCO","YF13H12"],"Ensembl":"ENSG00000105755","Gene description":"ETHE1 persulfide dioxygenase","Uniprot":["O95571"],"Chromosome":"19","Position":"43506719-43527230","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Dioxygenase","Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"256.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"1037.7","Paneth cells":"788.4","Proximal enterocytes":"376.3","Undifferentiated cells":"447.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+":"222.6","OE19":"360.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028360","HPA029028","HPA029029"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA028360":"AB_10599297","HPA029028":"AB_10602092","HPA029029":"AB_10601998"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.58e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.72e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Tissue RNA - adipose tissue [nTPM]":"24.4","Tissue RNA - adrenal gland [nTPM]":"27.9","Tissue RNA - amygdala [nTPM]":"16.1","Tissue RNA - appendix [nTPM]":"34.8","Tissue RNA - basal ganglia [nTPM]":"17.0","Tissue RNA - bone marrow [nTPM]":"45.8","Tissue RNA - breast [nTPM]":"26.7","Tissue RNA - cerebellum [nTPM]":"16.5","Tissue RNA - cerebral cortex [nTPM]":"17.3","Tissue RNA - cervix [nTPM]":"28.7","Tissue RNA - choroid plexus [nTPM]":"15.8","Tissue RNA - colon [nTPM]":"256.1","Tissue RNA - duodenum [nTPM]":"85.5","Tissue RNA - endometrium 1 [nTPM]":"18.3","Tissue RNA - epididymis [nTPM]":"29.8","Tissue RNA - esophagus [nTPM]":"81.0","Tissue RNA - fallopian tube [nTPM]":"20.6","Tissue RNA - gallbladder [nTPM]":"21.0","Tissue RNA - heart muscle [nTPM]":"18.8","Tissue RNA - hippocampal formation [nTPM]":"15.6","Tissue RNA - hypothalamus [nTPM]":"17.4","Tissue RNA - kidney [nTPM]":"40.4","Tissue RNA - liver [nTPM]":"52.7","Tissue RNA - lung [nTPM]":"30.5","Tissue RNA - lymph node [nTPM]":"23.4","Tissue RNA - medulla oblongata [nTPM]":"17.3","Tissue RNA - midbrain [nTPM]":"17.2","Tissue RNA - ovary [nTPM]":"13.5","Tissue RNA - pancreas [nTPM]":"28.9","Tissue RNA - parathyroid gland [nTPM]":"16.1","Tissue RNA - pituitary gland [nTPM]":"19.1","Tissue RNA - placenta [nTPM]":"26.3","Tissue RNA - pons [nTPM]":"16.6","Tissue RNA - prostate [nTPM]":"27.1","Tissue RNA - rectum [nTPM]":"226.6","Tissue RNA - retina [nTPM]":"3.2","Tissue RNA - salivary gland [nTPM]":"40.1","Tissue RNA - seminal vesicle [nTPM]":"18.5","Tissue RNA - skeletal muscle [nTPM]":"22.8","Tissue RNA - skin 1 [nTPM]":"27.2","Tissue RNA - small intestine [nTPM]":"77.0","Tissue RNA - smooth muscle [nTPM]":"35.6","Tissue RNA - spinal cord [nTPM]":"17.1","Tissue RNA - spleen [nTPM]":"27.8","Tissue RNA - stomach 1 [nTPM]":"37.8","Tissue RNA - testis [nTPM]":"3.0","Tissue RNA - thalamus [nTPM]":"18.2","Tissue RNA - thymus [nTPM]":"19.8","Tissue RNA - thyroid gland [nTPM]":"24.1","Tissue RNA - tongue [nTPM]":"21.9","Tissue RNA - tonsil [nTPM]":"41.7","Tissue RNA - urinary bladder [nTPM]":"34.4","Tissue RNA - vagina [nTPM]":"39.1","Tissue RNA - white matter [nTPM]":"17.2","Cell RNA - A-431 [nTPM]":"54.1","Cell RNA - A549 [nTPM]":"68.9","Cell RNA - AF22 [nTPM]":"14.1","Cell RNA - AN3-CA [nTPM]":"49.6","Cell RNA - ASC diff [nTPM]":"75.1","Cell RNA - ASC TERT1 [nTPM]":"50.9","Cell RNA - BEWO [nTPM]":"5.5","Cell RNA - BJ [nTPM]":"82.1","Cell RNA - BJ hTERT+ [nTPM]":"222.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"69.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"71.1","Cell RNA - CACO-2 [nTPM]":"21.1","Cell RNA - CAPAN-2 [nTPM]":"54.3","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"60.0","Cell RNA - fHDF\/TERT166 [nTPM]":"79.8","Cell RNA - GAMG [nTPM]":"22.2","Cell RNA - HaCaT [nTPM]":"42.9","Cell RNA - HAP1 [nTPM]":"20.6","Cell RNA - HBEC3-KT [nTPM]":"123.4","Cell RNA - HBF TERT88 [nTPM]":"19.6","Cell RNA - HDLM-2 [nTPM]":"26.2","Cell RNA - HEK 293 [nTPM]":"6.2","Cell RNA - HEL [nTPM]":"13.8","Cell RNA - HeLa [nTPM]":"29.7","Cell RNA - Hep G2 [nTPM]":"59.2","Cell RNA - HHSteC [nTPM]":"34.0","Cell RNA - HL-60 [nTPM]":"19.3","Cell RNA - HMC-1 [nTPM]":"18.4","Cell RNA - HSkMC [nTPM]":"52.2","Cell RNA - hTCEpi [nTPM]":"95.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.9","Cell RNA - hTERT-HME1 [nTPM]":"76.0","Cell RNA - hTERT-RPE1 [nTPM]":"92.2","Cell RNA - HUVEC TERT2 [nTPM]":"52.0","Cell RNA - JURKAT [nTPM]":"49.8","Cell RNA - K-562 [nTPM]":"9.0","Cell RNA - Karpas-707 [nTPM]":"87.6","Cell RNA - LHCN-M2 [nTPM]":"35.1","Cell RNA - MCF7 [nTPM]":"35.7","Cell RNA - MOLT-4 [nTPM]":"22.2","Cell RNA - NB-4 [nTPM]":"18.9","Cell RNA - NTERA-2 [nTPM]":"3.8","Cell RNA - OE19 [nTPM]":"360.5","Cell RNA - PC-3 [nTPM]":"32.9","Cell RNA - REH [nTPM]":"26.6","Cell RNA - RH-30 [nTPM]":"6.1","Cell RNA - RPMI-8226 [nTPM]":"12.0","Cell RNA - RPTEC TERT1 [nTPM]":"153.0","Cell RNA - RT4 [nTPM]":"110.9","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"16.6","Cell RNA - SiHa [nTPM]":"20.8","Cell RNA - SK-BR-3 [nTPM]":"74.8","Cell RNA - SK-MEL-30 [nTPM]":"50.6","Cell RNA - SuSa [nTPM]":"23.6","Cell RNA - T-47d [nTPM]":"22.4","Cell RNA - THP-1 [nTPM]":"34.3","Cell RNA - TIME [nTPM]":"41.6","Cell RNA - U-138 MG [nTPM]":"10.9","Cell RNA - U-2 OS [nTPM]":"46.9","Cell RNA - U-2197 [nTPM]":"13.1","Cell RNA - U-251 MG [nTPM]":"15.3","Cell RNA - U-266\/70 [nTPM]":"23.1","Cell RNA - U-266\/84 [nTPM]":"20.2","Cell RNA - U-698 [nTPM]":"1.4","Cell RNA - U-87 MG [nTPM]":"48.4","Cell RNA - U-937 [nTPM]":"83.8","Cell RNA - WM-115 [nTPM]":"57.7","Blood RNA - basophil [nTPM]":"24.2","Blood RNA - classical monocyte [nTPM]":"63.3","Blood RNA - eosinophil [nTPM]":"1.6","Blood RNA - gdT-cell [nTPM]":"41.1","Blood RNA - intermediate monocyte [nTPM]":"34.5","Blood RNA - MAIT T-cell [nTPM]":"48.3","Blood RNA - memory B-cell [nTPM]":"20.5","Blood RNA - memory CD4 T-cell [nTPM]":"47.6","Blood RNA - memory CD8 T-cell [nTPM]":"39.4","Blood RNA - myeloid DC [nTPM]":"95.8","Blood RNA - naive B-cell [nTPM]":"7.5","Blood RNA - naive CD4 T-cell [nTPM]":"36.4","Blood RNA - naive CD8 T-cell [nTPM]":"35.0","Blood RNA - neutrophil [nTPM]":"2.1","Blood RNA - NK-cell [nTPM]":"29.3","Blood RNA - non-classical monocyte [nTPM]":"22.8","Blood RNA - plasmacytoid DC [nTPM]":"17.9","Blood RNA - T-reg [nTPM]":"50.4","Blood RNA - total PBMC [nTPM]":"40.2","Brain RNA - amygdala [nTPM]":"16.1","Brain RNA - basal ganglia [nTPM]":"17.0","Brain RNA - cerebellum [nTPM]":"16.5","Brain RNA - cerebral cortex [nTPM]":"17.3","Brain RNA - hippocampal formation [nTPM]":"15.6","Brain RNA - hypothalamus [nTPM]":"17.4","Brain RNA - medulla oblongata [nTPM]":"17.3","Brain RNA - midbrain [nTPM]":"17.2","Brain RNA - pons [nTPM]":"16.6","Brain RNA - spinal cord [nTPM]":"17.1","Brain RNA - thalamus [nTPM]":"18.2","Brain RNA - white matter [nTPM]":"17.2","Single Cell Type RNA - Adipocytes [nTPM]":"32.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.4","Single Cell Type RNA - Astrocytes [nTPM]":"3.9","Single Cell Type RNA - B-cells [nTPM]":"25.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"34.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"82.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"242.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"57.5","Single Cell Type RNA - Bipolar cells [nTPM]":"9.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"85.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"95.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"47.1","Single Cell Type RNA - Club cells [nTPM]":"84.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"55.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"191.6","Single Cell Type RNA - dendritic cells [nTPM]":"38.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"1037.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"54.8","Single Cell Type RNA - Ductal cells [nTPM]":"71.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"31.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"41.2","Single Cell Type RNA - Endothelial cells [nTPM]":"44.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"63.7","Single Cell Type RNA - Erythroid cells [nTPM]":"17.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"63.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"95.7","Single Cell Type RNA - Fibroblasts [nTPM]":"42.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"53.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"68.2","Single Cell Type RNA - granulocytes [nTPM]":"38.0","Single Cell Type RNA - Granulosa cells [nTPM]":"12.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"42.1","Single Cell Type RNA - Hepatocytes [nTPM]":"89.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"115.1","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"324.2","Single Cell Type RNA - Ionocytes [nTPM]":"79.3","Single Cell Type RNA - Kupffer cells [nTPM]":"105.0","Single Cell Type RNA - Langerhans cells [nTPM]":"78.5","Single Cell Type RNA - Late spermatids [nTPM]":"2.1","Single Cell Type RNA - Leydig cells [nTPM]":"17.7","Single Cell Type RNA - Macrophages [nTPM]":"74.6","Single Cell Type RNA - Melanocytes [nTPM]":"80.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"78.5","Single Cell Type RNA - Muller glia cells [nTPM]":"11.7","Single Cell Type RNA - NK-cells [nTPM]":"63.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"102.7","Single Cell Type RNA - Paneth cells [nTPM]":"788.4","Single Cell Type RNA - Peritubular cells [nTPM]":"16.1","Single Cell Type RNA - Plasma cells [nTPM]":"34.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"75.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"376.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"136.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.8","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"32.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"45.1","Single Cell Type RNA - Spermatocytes [nTPM]":"2.1","Single Cell Type RNA - Spermatogonia [nTPM]":"6.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"82.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"23.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"92.5","Single Cell Type RNA - T-cells [nTPM]":"50.4","Single Cell Type RNA - Theca cells [nTPM]":"15.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"447.5","Single Cell Type RNA - Urothelial cells [nTPM]":"146.5"},{"Gene":"EXT1","Gene synonym":["LGCR","LGS","ttv"],"Ensembl":"ENSG00000182197","Gene description":"Exostosin glycosyltransferase 1","Uniprot":["Q16394"],"Chromosome":"8","Position":"117794490-118111826","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Hereditary multiple exostoses","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"229.6","Inhibitory neurons":"421.4","Microglial cells":"144.3","Oligodendrocyte precursor cells":"162.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+":"95.5","fHDF\/TERT166":"82.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044394"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"17000000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044394":"AB_10963838"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.04e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.20e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.64e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.1","Tissue RNA - adrenal gland [nTPM]":"4.2","Tissue RNA - amygdala [nTPM]":"2.0","Tissue RNA - appendix [nTPM]":"5.2","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"1.1","Tissue RNA - breast [nTPM]":"4.3","Tissue RNA - cerebellum [nTPM]":"2.3","Tissue RNA - cerebral cortex [nTPM]":"2.3","Tissue RNA - cervix [nTPM]":"7.6","Tissue RNA - choroid plexus [nTPM]":"3.9","Tissue RNA - colon [nTPM]":"7.7","Tissue RNA - duodenum [nTPM]":"14.1","Tissue RNA - endometrium 1 [nTPM]":"4.9","Tissue RNA - epididymis [nTPM]":"2.9","Tissue RNA - esophagus [nTPM]":"5.5","Tissue RNA - fallopian tube [nTPM]":"3.8","Tissue RNA - gallbladder [nTPM]":"5.8","Tissue RNA - heart muscle [nTPM]":"7.0","Tissue RNA - hippocampal formation [nTPM]":"3.4","Tissue RNA - hypothalamus [nTPM]":"1.3","Tissue RNA - kidney [nTPM]":"3.8","Tissue RNA - liver [nTPM]":"13.3","Tissue RNA - lung [nTPM]":"7.9","Tissue RNA - lymph node [nTPM]":"3.0","Tissue RNA - medulla oblongata [nTPM]":"1.1","Tissue RNA - midbrain [nTPM]":"2.1","Tissue RNA - ovary [nTPM]":"5.0","Tissue RNA - pancreas [nTPM]":"5.5","Tissue RNA - parathyroid gland [nTPM]":"3.3","Tissue RNA - pituitary gland [nTPM]":"1.8","Tissue RNA - placenta [nTPM]":"11.1","Tissue RNA - pons [nTPM]":"1.0","Tissue RNA - prostate [nTPM]":"5.0","Tissue RNA - rectum [nTPM]":"8.2","Tissue RNA - retina [nTPM]":"2.7","Tissue RNA - salivary gland [nTPM]":"3.2","Tissue RNA - seminal vesicle [nTPM]":"7.7","Tissue RNA - skeletal muscle [nTPM]":"1.5","Tissue RNA - skin 1 [nTPM]":"7.8","Tissue RNA - small intestine [nTPM]":"11.7","Tissue RNA - smooth muscle [nTPM]":"6.1","Tissue RNA - spinal cord [nTPM]":"1.4","Tissue RNA - spleen [nTPM]":"5.1","Tissue RNA - stomach 1 [nTPM]":"5.3","Tissue RNA - testis [nTPM]":"2.4","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"3.0","Tissue RNA - thyroid gland [nTPM]":"5.2","Tissue RNA - tongue [nTPM]":"2.4","Tissue RNA - tonsil [nTPM]":"3.8","Tissue RNA - urinary bladder [nTPM]":"11.8","Tissue RNA - vagina [nTPM]":"4.2","Tissue RNA - white matter [nTPM]":"1.9","Cell RNA - A-431 [nTPM]":"29.3","Cell RNA - A549 [nTPM]":"8.5","Cell RNA - AF22 [nTPM]":"13.5","Cell RNA - AN3-CA [nTPM]":"5.5","Cell RNA - ASC diff [nTPM]":"22.8","Cell RNA - ASC TERT1 [nTPM]":"23.0","Cell RNA - BEWO [nTPM]":"5.9","Cell RNA - BJ [nTPM]":"51.5","Cell RNA - BJ hTERT+ [nTPM]":"95.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"40.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"39.4","Cell RNA - CACO-2 [nTPM]":"10.0","Cell RNA - CAPAN-2 [nTPM]":"3.1","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"24.8","Cell RNA - fHDF\/TERT166 [nTPM]":"82.1","Cell RNA - GAMG [nTPM]":"24.0","Cell RNA - HaCaT [nTPM]":"19.8","Cell RNA - HAP1 [nTPM]":"5.0","Cell RNA - HBEC3-KT [nTPM]":"31.4","Cell RNA - HBF TERT88 [nTPM]":"55.7","Cell RNA - HDLM-2 [nTPM]":"12.5","Cell RNA - HEK 293 [nTPM]":"9.9","Cell RNA - HEL [nTPM]":"1.5","Cell RNA - HeLa [nTPM]":"5.9","Cell RNA - Hep G2 [nTPM]":"6.5","Cell RNA - HHSteC [nTPM]":"10.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.6","Cell RNA - HSkMC [nTPM]":"10.8","Cell RNA - hTCEpi [nTPM]":"10.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"38.8","Cell RNA - hTERT-HME1 [nTPM]":"38.5","Cell RNA - hTERT-RPE1 [nTPM]":"47.7","Cell RNA - HUVEC TERT2 [nTPM]":"28.1","Cell RNA - JURKAT [nTPM]":"2.9","Cell RNA - K-562 [nTPM]":"0.9","Cell RNA - Karpas-707 [nTPM]":"7.4","Cell RNA - LHCN-M2 [nTPM]":"18.7","Cell RNA - MCF7 [nTPM]":"3.2","Cell RNA - MOLT-4 [nTPM]":"1.8","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"4.6","Cell RNA - OE19 [nTPM]":"13.7","Cell RNA - PC-3 [nTPM]":"10.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"4.1","Cell RNA - RPMI-8226 [nTPM]":"1.3","Cell RNA - RPTEC TERT1 [nTPM]":"23.1","Cell RNA - RT4 [nTPM]":"7.6","Cell RNA - SCLC-21H [nTPM]":"4.5","Cell RNA - SH-SY5Y [nTPM]":"4.0","Cell RNA - SiHa [nTPM]":"8.0","Cell RNA - SK-BR-3 [nTPM]":"3.9","Cell RNA - SK-MEL-30 [nTPM]":"9.2","Cell RNA - SuSa [nTPM]":"32.6","Cell RNA - T-47d [nTPM]":"5.3","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"32.0","Cell RNA - U-138 MG [nTPM]":"35.2","Cell RNA - U-2 OS [nTPM]":"28.7","Cell RNA - U-2197 [nTPM]":"32.0","Cell RNA - U-251 MG [nTPM]":"15.8","Cell RNA - U-266\/70 [nTPM]":"5.5","Cell RNA - U-266\/84 [nTPM]":"5.1","Cell RNA - U-698 [nTPM]":"2.4","Cell RNA - U-87 MG [nTPM]":"36.5","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"9.2","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"2.0","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"2.3","Brain RNA - cerebral cortex [nTPM]":"2.3","Brain RNA - hippocampal formation [nTPM]":"3.4","Brain RNA - hypothalamus [nTPM]":"1.3","Brain RNA - medulla oblongata [nTPM]":"1.1","Brain RNA - midbrain [nTPM]":"2.1","Brain RNA - pons [nTPM]":"1.0","Brain RNA - spinal cord [nTPM]":"1.4","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"1.9","Single Cell Type RNA - Adipocytes [nTPM]":"21.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.0","Single Cell Type RNA - Astrocytes [nTPM]":"127.3","Single Cell Type RNA - B-cells [nTPM]":"3.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"54.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"27.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"23.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"13.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.5","Single Cell Type RNA - dendritic cells [nTPM]":"5.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"49.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"37.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"37.1","Single Cell Type RNA - Endothelial cells [nTPM]":"25.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"229.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"20.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.9","Single Cell Type RNA - Fibroblasts [nTPM]":"32.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.2","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"108.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.8","Single Cell Type RNA - Hepatocytes [nTPM]":"32.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.5","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"421.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"25.5","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"37.9","Single Cell Type RNA - Langerhans cells [nTPM]":"13.9","Single Cell Type RNA - Late spermatids [nTPM]":"2.7","Single Cell Type RNA - Leydig cells [nTPM]":"17.4","Single Cell Type RNA - Macrophages [nTPM]":"9.6","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"144.3","Single Cell Type RNA - monocytes [nTPM]":"8.1","Single Cell Type RNA - Muller glia cells [nTPM]":"5.9","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"162.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"101.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"27.4","Single Cell Type RNA - Paneth cells [nTPM]":"16.1","Single Cell Type RNA - Peritubular cells [nTPM]":"36.1","Single Cell Type RNA - Plasma cells [nTPM]":"5.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"44.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"22.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"36.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"5.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"47.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.2","Single Cell Type RNA - T-cells [nTPM]":"4.2","Single Cell Type RNA - Theca cells [nTPM]":"35.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.3","Single Cell Type RNA - Urothelial cells [nTPM]":"26.8"},{"Gene":"EXT2","Gene synonym":["SOTV"],"Ensembl":"ENSG00000151348","Gene description":"Exostosin glycosyltransferase 2","Uniprot":["Q93063"],"Chromosome":"11","Position":"44095673-44251962","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Epilepsy","Hereditary multiple exostoses","Mental retardation","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078409"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"39000000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA078409":"AB_2686884"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.50e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.36e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Tissue RNA - adipose tissue [nTPM]":"33.5","Tissue RNA - adrenal gland [nTPM]":"22.8","Tissue RNA - amygdala [nTPM]":"14.4","Tissue RNA - appendix [nTPM]":"22.1","Tissue RNA - basal ganglia [nTPM]":"15.4","Tissue RNA - bone marrow [nTPM]":"11.2","Tissue RNA - breast [nTPM]":"29.3","Tissue RNA - cerebellum [nTPM]":"15.4","Tissue RNA - cerebral cortex [nTPM]":"16.3","Tissue RNA - cervix [nTPM]":"36.1","Tissue RNA - choroid plexus [nTPM]":"17.5","Tissue RNA - colon [nTPM]":"29.1","Tissue RNA - duodenum [nTPM]":"26.5","Tissue RNA - endometrium 1 [nTPM]":"43.1","Tissue RNA - epididymis [nTPM]":"33.3","Tissue RNA - esophagus [nTPM]":"20.1","Tissue RNA - fallopian tube [nTPM]":"33.7","Tissue RNA - gallbladder [nTPM]":"28.1","Tissue RNA - heart muscle [nTPM]":"27.3","Tissue RNA - hippocampal formation [nTPM]":"15.6","Tissue RNA - hypothalamus [nTPM]":"18.1","Tissue RNA - kidney [nTPM]":"26.5","Tissue RNA - liver [nTPM]":"26.9","Tissue RNA - lung [nTPM]":"27.9","Tissue RNA - lymph node [nTPM]":"16.0","Tissue RNA - medulla oblongata [nTPM]":"15.5","Tissue RNA - midbrain [nTPM]":"16.0","Tissue RNA - ovary [nTPM]":"33.5","Tissue RNA - pancreas [nTPM]":"26.5","Tissue RNA - parathyroid gland [nTPM]":"28.9","Tissue RNA - pituitary gland [nTPM]":"20.1","Tissue RNA - placenta [nTPM]":"61.9","Tissue RNA - pons [nTPM]":"15.5","Tissue RNA - prostate [nTPM]":"29.8","Tissue RNA - rectum [nTPM]":"28.7","Tissue RNA - retina [nTPM]":"20.9","Tissue RNA - salivary gland [nTPM]":"26.7","Tissue RNA - seminal vesicle [nTPM]":"30.2","Tissue RNA - skeletal muscle [nTPM]":"16.2","Tissue RNA - skin 1 [nTPM]":"25.8","Tissue RNA - small intestine [nTPM]":"31.0","Tissue RNA - smooth muscle [nTPM]":"49.3","Tissue RNA - spinal cord [nTPM]":"14.7","Tissue RNA - spleen [nTPM]":"21.6","Tissue RNA - stomach 1 [nTPM]":"23.8","Tissue RNA - testis [nTPM]":"21.6","Tissue RNA - thalamus [nTPM]":"19.4","Tissue RNA - thymus [nTPM]":"15.2","Tissue RNA - thyroid gland [nTPM]":"27.6","Tissue RNA - tongue [nTPM]":"18.4","Tissue RNA - tonsil [nTPM]":"17.3","Tissue RNA - urinary bladder [nTPM]":"29.7","Tissue RNA - vagina [nTPM]":"28.5","Tissue RNA - white matter [nTPM]":"16.1","Cell RNA - A-431 [nTPM]":"57.9","Cell RNA - A549 [nTPM]":"71.6","Cell RNA - AF22 [nTPM]":"38.3","Cell RNA - AN3-CA [nTPM]":"121.5","Cell RNA - ASC diff [nTPM]":"170.4","Cell RNA - ASC TERT1 [nTPM]":"124.2","Cell RNA - BEWO [nTPM]":"60.8","Cell RNA - BJ [nTPM]":"181.1","Cell RNA - BJ hTERT+ [nTPM]":"198.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"93.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"125.1","Cell RNA - CACO-2 [nTPM]":"51.2","Cell RNA - CAPAN-2 [nTPM]":"36.5","Cell RNA - Daudi [nTPM]":"40.4","Cell RNA - EFO-21 [nTPM]":"82.1","Cell RNA - fHDF\/TERT166 [nTPM]":"188.8","Cell RNA - GAMG [nTPM]":"98.5","Cell RNA - HaCaT [nTPM]":"90.0","Cell RNA - HAP1 [nTPM]":"41.0","Cell RNA - HBEC3-KT [nTPM]":"114.0","Cell RNA - HBF TERT88 [nTPM]":"110.0","Cell RNA - HDLM-2 [nTPM]":"83.2","Cell RNA - HEK 293 [nTPM]":"71.5","Cell RNA - HEL [nTPM]":"38.4","Cell RNA - HeLa [nTPM]":"33.7","Cell RNA - Hep G2 [nTPM]":"39.7","Cell RNA - HHSteC [nTPM]":"67.5","Cell RNA - HL-60 [nTPM]":"37.5","Cell RNA - HMC-1 [nTPM]":"76.6","Cell RNA - HSkMC [nTPM]":"97.7","Cell RNA - hTCEpi [nTPM]":"73.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"56.3","Cell RNA - hTERT-HME1 [nTPM]":"86.6","Cell RNA - hTERT-RPE1 [nTPM]":"108.8","Cell RNA - HUVEC TERT2 [nTPM]":"132.7","Cell RNA - JURKAT [nTPM]":"34.8","Cell RNA - K-562 [nTPM]":"50.0","Cell RNA - Karpas-707 [nTPM]":"63.9","Cell RNA - LHCN-M2 [nTPM]":"68.4","Cell RNA - MCF7 [nTPM]":"40.3","Cell RNA - MOLT-4 [nTPM]":"25.9","Cell RNA - NB-4 [nTPM]":"22.3","Cell RNA - NTERA-2 [nTPM]":"43.8","Cell RNA - OE19 [nTPM]":"67.1","Cell RNA - PC-3 [nTPM]":"70.9","Cell RNA - REH [nTPM]":"32.3","Cell RNA - RH-30 [nTPM]":"116.1","Cell RNA - RPMI-8226 [nTPM]":"21.1","Cell RNA - RPTEC TERT1 [nTPM]":"53.9","Cell RNA - RT4 [nTPM]":"49.1","Cell RNA - SCLC-21H [nTPM]":"30.9","Cell RNA - SH-SY5Y [nTPM]":"35.5","Cell RNA - SiHa [nTPM]":"118.1","Cell RNA - SK-BR-3 [nTPM]":"41.4","Cell RNA - SK-MEL-30 [nTPM]":"28.1","Cell RNA - SuSa [nTPM]":"67.0","Cell RNA - T-47d [nTPM]":"69.8","Cell RNA - THP-1 [nTPM]":"37.2","Cell RNA - TIME [nTPM]":"137.8","Cell RNA - U-138 MG [nTPM]":"127.4","Cell RNA - U-2 OS [nTPM]":"90.6","Cell RNA - U-2197 [nTPM]":"133.1","Cell RNA - U-251 MG [nTPM]":"111.4","Cell RNA - U-266\/70 [nTPM]":"33.4","Cell RNA - U-266\/84 [nTPM]":"46.0","Cell RNA - U-698 [nTPM]":"30.4","Cell RNA - U-87 MG [nTPM]":"84.7","Cell RNA - U-937 [nTPM]":"27.9","Cell RNA - WM-115 [nTPM]":"140.0","Blood RNA - basophil [nTPM]":"15.2","Blood RNA - classical monocyte [nTPM]":"17.5","Blood RNA - eosinophil [nTPM]":"19.4","Blood RNA - gdT-cell [nTPM]":"20.9","Blood RNA - intermediate monocyte [nTPM]":"17.7","Blood RNA - MAIT T-cell [nTPM]":"23.5","Blood RNA - memory B-cell [nTPM]":"9.0","Blood RNA - memory CD4 T-cell [nTPM]":"16.5","Blood RNA - memory CD8 T-cell [nTPM]":"19.3","Blood RNA - myeloid DC [nTPM]":"21.3","Blood RNA - naive B-cell [nTPM]":"8.8","Blood RNA - naive CD4 T-cell [nTPM]":"15.4","Blood RNA - naive CD8 T-cell [nTPM]":"15.2","Blood RNA - neutrophil [nTPM]":"3.4","Blood RNA - NK-cell [nTPM]":"26.3","Blood RNA - non-classical monocyte [nTPM]":"12.8","Blood RNA - plasmacytoid DC [nTPM]":"7.4","Blood RNA - T-reg [nTPM]":"14.2","Blood RNA - total PBMC [nTPM]":"15.5","Brain RNA - amygdala [nTPM]":"14.4","Brain RNA - basal ganglia [nTPM]":"15.4","Brain RNA - cerebellum [nTPM]":"15.4","Brain RNA - cerebral cortex [nTPM]":"16.3","Brain RNA - hippocampal formation [nTPM]":"15.6","Brain RNA - hypothalamus [nTPM]":"18.1","Brain RNA - medulla oblongata [nTPM]":"15.5","Brain RNA - midbrain [nTPM]":"16.0","Brain RNA - pons [nTPM]":"15.5","Brain RNA - spinal cord [nTPM]":"14.7","Brain RNA - thalamus [nTPM]":"19.4","Brain RNA - white matter [nTPM]":"16.1","Single Cell Type RNA - Adipocytes [nTPM]":"24.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.6","Single Cell Type RNA - Astrocytes [nTPM]":"41.4","Single Cell Type RNA - B-cells [nTPM]":"8.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"11.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"13.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"34.3","Single Cell Type RNA - dendritic cells [nTPM]":"10.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"21.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"33.5","Single Cell Type RNA - Early spermatids [nTPM]":"43.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.1","Single Cell Type RNA - Endothelial cells [nTPM]":"19.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"6.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"64.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"37.0","Single Cell Type RNA - Fibroblasts [nTPM]":"32.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.5","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"22.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.9","Single Cell Type RNA - Hepatocytes [nTPM]":"18.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.3","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"63.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.9","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"10.8","Single Cell Type RNA - Langerhans cells [nTPM]":"7.2","Single Cell Type RNA - Late spermatids [nTPM]":"23.0","Single Cell Type RNA - Leydig cells [nTPM]":"27.4","Single Cell Type RNA - Macrophages [nTPM]":"10.4","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"28.1","Single Cell Type RNA - monocytes [nTPM]":"10.2","Single Cell Type RNA - Muller glia cells [nTPM]":"17.4","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"50.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"51.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"24.0","Single Cell Type RNA - Paneth cells [nTPM]":"14.9","Single Cell Type RNA - Peritubular cells [nTPM]":"28.6","Single Cell Type RNA - Plasma cells [nTPM]":"7.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"31.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.0","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.7","Single Cell Type RNA - Spermatocytes [nTPM]":"51.2","Single Cell Type RNA - Spermatogonia [nTPM]":"24.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"35.3","Single Cell Type RNA - T-cells [nTPM]":"9.2","Single Cell Type RNA - Theca cells [nTPM]":"12.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.0","Single Cell Type RNA - Urothelial cells [nTPM]":"15.3"},{"Gene":"EXTL3","Gene synonym":["botv","REGR"],"Ensembl":"ENSG00000012232","Gene description":"Exostosin like glycosyltransferase 3","Uniprot":["O43909"],"Chromosome":"8","Position":"28600469-28755599","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant","Dwarfism","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"5.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025387"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 23: Spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025387":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.14e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.47e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.8","Tissue RNA - adrenal gland [nTPM]":"16.5","Tissue RNA - amygdala [nTPM]":"11.3","Tissue RNA - appendix [nTPM]":"7.2","Tissue RNA - basal ganglia [nTPM]":"12.0","Tissue RNA - bone marrow [nTPM]":"3.8","Tissue RNA - breast [nTPM]":"6.3","Tissue RNA - cerebellum [nTPM]":"7.6","Tissue RNA - cerebral cortex [nTPM]":"13.7","Tissue RNA - cervix [nTPM]":"8.9","Tissue RNA - choroid plexus [nTPM]":"5.8","Tissue RNA - colon [nTPM]":"11.1","Tissue RNA - duodenum [nTPM]":"5.5","Tissue RNA - endometrium 1 [nTPM]":"13.8","Tissue RNA - epididymis [nTPM]":"5.4","Tissue RNA - esophagus [nTPM]":"12.3","Tissue RNA - fallopian tube [nTPM]":"11.3","Tissue RNA - gallbladder [nTPM]":"7.9","Tissue RNA - heart muscle [nTPM]":"31.1","Tissue RNA - hippocampal formation [nTPM]":"14.7","Tissue RNA - hypothalamus [nTPM]":"10.4","Tissue RNA - kidney [nTPM]":"7.0","Tissue RNA - liver [nTPM]":"6.2","Tissue RNA - lung [nTPM]":"8.6","Tissue RNA - lymph node [nTPM]":"5.4","Tissue RNA - medulla oblongata [nTPM]":"10.7","Tissue RNA - midbrain [nTPM]":"14.3","Tissue RNA - ovary [nTPM]":"10.0","Tissue RNA - pancreas [nTPM]":"11.9","Tissue RNA - parathyroid gland [nTPM]":"18.9","Tissue RNA - pituitary gland [nTPM]":"10.3","Tissue RNA - placenta [nTPM]":"13.8","Tissue RNA - pons [nTPM]":"7.2","Tissue RNA - prostate [nTPM]":"8.5","Tissue RNA - rectum [nTPM]":"5.4","Tissue RNA - retina [nTPM]":"11.2","Tissue RNA - salivary gland [nTPM]":"8.1","Tissue RNA - seminal vesicle [nTPM]":"11.8","Tissue RNA - skeletal muscle [nTPM]":"20.8","Tissue RNA - skin 1 [nTPM]":"11.1","Tissue RNA - small intestine [nTPM]":"6.7","Tissue RNA - smooth muscle [nTPM]":"17.9","Tissue RNA - spinal cord [nTPM]":"8.9","Tissue RNA - spleen [nTPM]":"8.6","Tissue RNA - stomach 1 [nTPM]":"9.0","Tissue RNA - testis [nTPM]":"10.3","Tissue RNA - thalamus [nTPM]":"23.4","Tissue RNA - thymus [nTPM]":"6.4","Tissue RNA - thyroid gland [nTPM]":"7.7","Tissue RNA - tongue [nTPM]":"22.7","Tissue RNA - tonsil [nTPM]":"4.8","Tissue RNA - urinary bladder [nTPM]":"10.6","Tissue RNA - vagina [nTPM]":"7.2","Tissue RNA - white matter [nTPM]":"12.7","Cell RNA - A-431 [nTPM]":"45.3","Cell RNA - A549 [nTPM]":"33.6","Cell RNA - AF22 [nTPM]":"70.1","Cell RNA - AN3-CA [nTPM]":"37.0","Cell RNA - ASC diff [nTPM]":"18.8","Cell RNA - ASC TERT1 [nTPM]":"18.5","Cell RNA - BEWO [nTPM]":"15.6","Cell RNA - BJ [nTPM]":"33.7","Cell RNA - BJ hTERT+ [nTPM]":"32.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.4","Cell RNA - CACO-2 [nTPM]":"28.9","Cell RNA - CAPAN-2 [nTPM]":"15.9","Cell RNA - Daudi [nTPM]":"12.2","Cell RNA - EFO-21 [nTPM]":"46.6","Cell RNA - fHDF\/TERT166 [nTPM]":"40.1","Cell RNA - GAMG [nTPM]":"28.2","Cell RNA - HaCaT [nTPM]":"29.7","Cell RNA - HAP1 [nTPM]":"34.5","Cell RNA - HBEC3-KT [nTPM]":"55.1","Cell RNA - HBF TERT88 [nTPM]":"22.4","Cell RNA - HDLM-2 [nTPM]":"8.9","Cell RNA - HEK 293 [nTPM]":"18.9","Cell RNA - HEL [nTPM]":"17.2","Cell RNA - HeLa [nTPM]":"15.7","Cell RNA - Hep G2 [nTPM]":"14.3","Cell RNA - HHSteC [nTPM]":"9.8","Cell RNA - HL-60 [nTPM]":"8.6","Cell RNA - HMC-1 [nTPM]":"46.9","Cell RNA - HSkMC [nTPM]":"22.2","Cell RNA - hTCEpi [nTPM]":"36.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.9","Cell RNA - hTERT-HME1 [nTPM]":"14.6","Cell RNA - hTERT-RPE1 [nTPM]":"16.9","Cell RNA - HUVEC TERT2 [nTPM]":"44.3","Cell RNA - JURKAT [nTPM]":"17.4","Cell RNA - K-562 [nTPM]":"16.2","Cell RNA - Karpas-707 [nTPM]":"15.4","Cell RNA - LHCN-M2 [nTPM]":"16.5","Cell RNA - MCF7 [nTPM]":"8.5","Cell RNA - MOLT-4 [nTPM]":"15.5","Cell RNA - NB-4 [nTPM]":"4.7","Cell RNA - NTERA-2 [nTPM]":"49.2","Cell RNA - OE19 [nTPM]":"13.3","Cell RNA - PC-3 [nTPM]":"13.6","Cell RNA - REH [nTPM]":"18.4","Cell RNA - RH-30 [nTPM]":"31.3","Cell RNA - RPMI-8226 [nTPM]":"7.1","Cell RNA - RPTEC TERT1 [nTPM]":"31.2","Cell RNA - RT4 [nTPM]":"29.0","Cell RNA - SCLC-21H [nTPM]":"15.2","Cell RNA - SH-SY5Y [nTPM]":"26.6","Cell RNA - SiHa [nTPM]":"14.3","Cell RNA - SK-BR-3 [nTPM]":"8.6","Cell RNA - SK-MEL-30 [nTPM]":"17.3","Cell RNA - SuSa [nTPM]":"22.0","Cell RNA - T-47d [nTPM]":"8.4","Cell RNA - THP-1 [nTPM]":"9.4","Cell RNA - TIME [nTPM]":"34.9","Cell RNA - U-138 MG [nTPM]":"26.6","Cell RNA - U-2 OS [nTPM]":"62.7","Cell RNA - U-2197 [nTPM]":"25.4","Cell RNA - U-251 MG [nTPM]":"28.9","Cell RNA - U-266\/70 [nTPM]":"7.9","Cell RNA - U-266\/84 [nTPM]":"17.9","Cell RNA - U-698 [nTPM]":"13.5","Cell RNA - U-87 MG [nTPM]":"22.5","Cell RNA - U-937 [nTPM]":"10.3","Cell RNA - WM-115 [nTPM]":"23.7","Blood RNA - basophil [nTPM]":"3.0","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"2.0","Blood RNA - gdT-cell [nTPM]":"1.7","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.7","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"1.3","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"5.7","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"11.3","Brain RNA - basal ganglia [nTPM]":"12.0","Brain RNA - cerebellum [nTPM]":"7.6","Brain RNA - cerebral cortex [nTPM]":"13.7","Brain RNA - hippocampal formation [nTPM]":"14.7","Brain RNA - hypothalamus [nTPM]":"10.4","Brain RNA - medulla oblongata [nTPM]":"10.7","Brain RNA - midbrain [nTPM]":"14.3","Brain RNA - pons [nTPM]":"7.2","Brain RNA - spinal cord [nTPM]":"8.9","Brain RNA - thalamus [nTPM]":"23.4","Brain RNA - white matter [nTPM]":"12.7","Single Cell Type RNA - Adipocytes [nTPM]":"6.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.4","Single Cell Type RNA - Astrocytes [nTPM]":"10.4","Single Cell Type RNA - B-cells [nTPM]":"2.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"17.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"26.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"5.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.7","Single Cell Type RNA - dendritic cells [nTPM]":"7.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.7","Single Cell Type RNA - Early spermatids [nTPM]":"32.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.0","Single Cell Type RNA - Endothelial cells [nTPM]":"7.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"20.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"16.9","Single Cell Type RNA - Fibroblasts [nTPM]":"6.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.9","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"3.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.2","Single Cell Type RNA - Hepatocytes [nTPM]":"9.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.4","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"19.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.4","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"6.6","Single Cell Type RNA - Langerhans cells [nTPM]":"2.5","Single Cell Type RNA - Late spermatids [nTPM]":"10.1","Single Cell Type RNA - Leydig cells [nTPM]":"9.9","Single Cell Type RNA - Macrophages [nTPM]":"6.1","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"5.7","Single Cell Type RNA - Muller glia cells [nTPM]":"6.7","Single Cell Type RNA - NK-cells [nTPM]":"23.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.3","Single Cell Type RNA - Paneth cells [nTPM]":"2.4","Single Cell Type RNA - Peritubular cells [nTPM]":"14.3","Single Cell Type RNA - Plasma cells [nTPM]":"4.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.2","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.6","Single Cell Type RNA - Spermatocytes [nTPM]":"4.3","Single Cell Type RNA - Spermatogonia [nTPM]":"9.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.2","Single Cell Type RNA - T-cells [nTPM]":"4.5","Single Cell Type RNA - Theca cells [nTPM]":"8.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.1","Single Cell Type RNA - Urothelial cells [nTPM]":"3.1"},{"Gene":"EYA1","Gene synonym":["BOR"],"Ensembl":"ENSG00000104313","Gene description":"EYA transcriptional coactivator and phosphatase 1","Uniprot":["Q99502"],"Chromosome":"8","Position":"71197433-71592025","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Transcription","Transcription regulation"],"Molecular function":["Activator","Chromatin regulator","Developmental protein","Hydrolase","Protein phosphatase"],"Disease involvement":["Deafness","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"18.7","parathyroid gland":"23.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Astrocytes":"214.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AN3-CA":"27.6","RH-30":"21.3","RPMI-8226":"9.5","SH-SY5Y":"51.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"20.7"},"Antibody":["HPA028917"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA028917":"AB_2672826"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.6","Tissue RNA - adrenal gland [nTPM]":"0.6","Tissue RNA - amygdala [nTPM]":"2.8","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"7.8","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"2.1","Tissue RNA - cervix [nTPM]":"5.1","Tissue RNA - choroid plexus [nTPM]":"18.7","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"2.0","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"4.5","Tissue RNA - hippocampal formation [nTPM]":"1.3","Tissue RNA - hypothalamus [nTPM]":"2.5","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"2.1","Tissue RNA - midbrain [nTPM]":"4.9","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"23.7","Tissue RNA - pituitary gland [nTPM]":"10.8","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"2.3","Tissue RNA - prostate [nTPM]":"12.0","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"0.8","Tissue RNA - seminal vesicle [nTPM]":"4.0","Tissue RNA - skeletal muscle [nTPM]":"2.8","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.8","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"4.6","Tissue RNA - thymus [nTPM]":"11.7","Tissue RNA - thyroid gland [nTPM]":"0.6","Tissue RNA - tongue [nTPM]":"2.5","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"2.6","Tissue RNA - vagina [nTPM]":"4.3","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"6.4","Cell RNA - AN3-CA [nTPM]":"27.6","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"2.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.9","Cell RNA - HBEC3-KT [nTPM]":"1.6","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"4.7","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"2.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"6.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"2.0","Cell RNA - LHCN-M2 [nTPM]":"1.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"2.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"1.5","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"21.3","Cell RNA - RPMI-8226 [nTPM]":"9.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"2.2","Cell RNA - SH-SY5Y [nTPM]":"51.4","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"1.6","Cell RNA - SuSa [nTPM]":"5.9","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.5","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"6.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"2.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.8","Brain RNA - basal ganglia [nTPM]":"7.8","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"2.1","Brain RNA - hippocampal formation [nTPM]":"1.3","Brain RNA - hypothalamus [nTPM]":"2.5","Brain RNA - medulla oblongata [nTPM]":"2.1","Brain RNA - midbrain [nTPM]":"4.9","Brain RNA - pons [nTPM]":"2.3","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"4.6","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"214.5","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"7.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"4.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"1.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"6.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"1.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"EYA4","Gene synonym":["CMD1J","DFNA10"],"Ensembl":"ENSG00000112319","Gene description":"EYA transcriptional coactivator and phosphatase 4","Uniprot":["O95677"],"Chromosome":"6","Position":"133240598-133532128","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Transcription","Transcription regulation"],"Molecular function":["Activator","Chromatin regulator","Developmental protein","Hydrolase","Protein phosphatase"],"Disease involvement":["Cardiomyopathy","Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"27.6","tongue":"21.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"46.0","Inhibitory neurons":"139.0","Oligodendrocytes":"79.2","Skeletal myocytes":"26.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"25.4","GAMG":"25.6","HeLa":"74.3","RH-30":"23.8","U-87 MG":"24.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004805","HPA038771","HPA038772"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA004805":"AB_10669750","HPA038771":"AB_10671865","HPA038772":"AB_10673119"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-9"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.27e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.1","Tissue RNA - adrenal gland [nTPM]":"2.5","Tissue RNA - amygdala [nTPM]":"2.6","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"1.9","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"2.2","Tissue RNA - cerebral cortex [nTPM]":"1.9","Tissue RNA - cervix [nTPM]":"2.6","Tissue RNA - choroid plexus [nTPM]":"13.3","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.5","Tissue RNA - epididymis [nTPM]":"1.2","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"7.4","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"5.8","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"1.2","Tissue RNA - kidney [nTPM]":"5.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"1.8","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"5.6","Tissue RNA - midbrain [nTPM]":"7.9","Tissue RNA - ovary [nTPM]":"1.2","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"4.5","Tissue RNA - prostate [nTPM]":"5.7","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"11.8","Tissue RNA - skeletal muscle [nTPM]":"27.6","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"4.5","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"3.0","Tissue RNA - thalamus [nTPM]":"3.3","Tissue RNA - thymus [nTPM]":"6.6","Tissue RNA - thyroid gland [nTPM]":"2.1","Tissue RNA - tongue [nTPM]":"21.3","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"2.2","Tissue RNA - vagina [nTPM]":"2.3","Tissue RNA - white matter [nTPM]":"4.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"25.4","Cell RNA - AF22 [nTPM]":"2.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"20.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.9","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"19.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"25.6","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"15.4","Cell RNA - HBEC3-KT [nTPM]":"6.7","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"20.2","Cell RNA - HEL [nTPM]":"2.8","Cell RNA - HeLa [nTPM]":"74.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.6","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"6.8","Cell RNA - HSkMC [nTPM]":"5.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.4","Cell RNA - hTERT-HME1 [nTPM]":"4.5","Cell RNA - hTERT-RPE1 [nTPM]":"3.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"10.7","Cell RNA - LHCN-M2 [nTPM]":"8.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"1.6","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"23.8","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"3.9","Cell RNA - SCLC-21H [nTPM]":"3.7","Cell RNA - SH-SY5Y [nTPM]":"4.1","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"11.4","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"18.4","Cell RNA - U-266\/70 [nTPM]":"7.2","Cell RNA - U-266\/84 [nTPM]":"3.4","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"24.6","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"2.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.6","Brain RNA - basal ganglia [nTPM]":"1.9","Brain RNA - cerebellum [nTPM]":"2.2","Brain RNA - cerebral cortex [nTPM]":"1.9","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"1.2","Brain RNA - medulla oblongata [nTPM]":"5.6","Brain RNA - midbrain [nTPM]":"7.9","Brain RNA - pons [nTPM]":"4.5","Brain RNA - spinal cord [nTPM]":"4.5","Brain RNA - thalamus [nTPM]":"3.3","Brain RNA - white matter [nTPM]":"4.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.8","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"6.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"46.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"4.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"139.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"7.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"79.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"26.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.3","Single Cell Type RNA - Spermatocytes [nTPM]":"7.9","Single Cell Type RNA - Spermatogonia [nTPM]":"7.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"1.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"FAH","Gene synonym":[],"Ensembl":"ENSG00000103876","Gene description":"Fumarylacetoacetate hydrolase","Uniprot":["P16930"],"Chromosome":"15","Position":"80152490-80186946","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Phenylalanine catabolism","Tyrosine catabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"301.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"266.8","Proximal tubular cells":"305.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"23.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"34.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HHSteC":"316.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041370","HPA044093"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"220000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA041370":"AB_2677438","HPA044093":"AB_2678806"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.51e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Tissue RNA - adipose tissue [nTPM]":"99.2","Tissue RNA - adrenal gland [nTPM]":"65.4","Tissue RNA - amygdala [nTPM]":"16.0","Tissue RNA - appendix [nTPM]":"7.0","Tissue RNA - basal ganglia [nTPM]":"17.1","Tissue RNA - bone marrow [nTPM]":"20.0","Tissue RNA - breast [nTPM]":"59.0","Tissue RNA - cerebellum [nTPM]":"16.6","Tissue RNA - cerebral cortex [nTPM]":"21.1","Tissue RNA - cervix [nTPM]":"19.2","Tissue RNA - choroid plexus [nTPM]":"15.1","Tissue RNA - colon [nTPM]":"13.8","Tissue RNA - duodenum [nTPM]":"14.6","Tissue RNA - endometrium 1 [nTPM]":"19.3","Tissue RNA - epididymis [nTPM]":"50.4","Tissue RNA - esophagus [nTPM]":"15.2","Tissue RNA - fallopian tube [nTPM]":"23.0","Tissue RNA - gallbladder [nTPM]":"9.7","Tissue RNA - heart muscle [nTPM]":"20.3","Tissue RNA - hippocampal formation [nTPM]":"16.3","Tissue RNA - hypothalamus [nTPM]":"18.8","Tissue RNA - kidney [nTPM]":"65.0","Tissue RNA - liver [nTPM]":"301.5","Tissue RNA - lung [nTPM]":"20.0","Tissue RNA - lymph node [nTPM]":"5.7","Tissue RNA - medulla oblongata [nTPM]":"17.9","Tissue RNA - midbrain [nTPM]":"19.6","Tissue RNA - ovary [nTPM]":"26.4","Tissue RNA - pancreas [nTPM]":"9.9","Tissue RNA - parathyroid gland [nTPM]":"18.4","Tissue RNA - pituitary gland [nTPM]":"16.8","Tissue RNA - placenta [nTPM]":"7.8","Tissue RNA - pons [nTPM]":"16.9","Tissue RNA - prostate [nTPM]":"16.6","Tissue RNA - rectum [nTPM]":"11.9","Tissue RNA - retina [nTPM]":"1.6","Tissue RNA - salivary gland [nTPM]":"14.8","Tissue RNA - seminal vesicle [nTPM]":"13.6","Tissue RNA - skeletal muscle [nTPM]":"31.0","Tissue RNA - skin 1 [nTPM]":"10.9","Tissue RNA - small intestine [nTPM]":"16.8","Tissue RNA - smooth muscle [nTPM]":"13.5","Tissue RNA - spinal cord [nTPM]":"17.2","Tissue RNA - spleen [nTPM]":"19.1","Tissue RNA - stomach 1 [nTPM]":"14.2","Tissue RNA - testis [nTPM]":"20.8","Tissue RNA - thalamus [nTPM]":"17.4","Tissue RNA - thymus [nTPM]":"6.7","Tissue RNA - thyroid gland [nTPM]":"14.5","Tissue RNA - tongue [nTPM]":"27.7","Tissue RNA - tonsil [nTPM]":"5.8","Tissue RNA - urinary bladder [nTPM]":"16.4","Tissue RNA - vagina [nTPM]":"15.8","Tissue RNA - white matter [nTPM]":"17.5","Cell RNA - A-431 [nTPM]":"20.1","Cell RNA - A549 [nTPM]":"34.4","Cell RNA - AF22 [nTPM]":"13.5","Cell RNA - AN3-CA [nTPM]":"17.0","Cell RNA - ASC diff [nTPM]":"60.2","Cell RNA - ASC TERT1 [nTPM]":"62.2","Cell RNA - BEWO [nTPM]":"32.9","Cell RNA - BJ [nTPM]":"24.3","Cell RNA - BJ hTERT+ [nTPM]":"56.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"26.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"22.3","Cell RNA - CACO-2 [nTPM]":"22.0","Cell RNA - CAPAN-2 [nTPM]":"35.9","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"39.0","Cell RNA - fHDF\/TERT166 [nTPM]":"52.6","Cell RNA - GAMG [nTPM]":"36.8","Cell RNA - HaCaT [nTPM]":"29.1","Cell RNA - HAP1 [nTPM]":"46.8","Cell RNA - HBEC3-KT [nTPM]":"59.6","Cell RNA - HBF TERT88 [nTPM]":"25.1","Cell RNA - HDLM-2 [nTPM]":"12.5","Cell RNA - HEK 293 [nTPM]":"28.5","Cell RNA - HEL [nTPM]":"166.6","Cell RNA - HeLa [nTPM]":"18.0","Cell RNA - Hep G2 [nTPM]":"112.1","Cell RNA - HHSteC [nTPM]":"316.6","Cell RNA - HL-60 [nTPM]":"79.6","Cell RNA - HMC-1 [nTPM]":"88.8","Cell RNA - HSkMC [nTPM]":"107.5","Cell RNA - hTCEpi [nTPM]":"37.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.9","Cell RNA - hTERT-HME1 [nTPM]":"39.7","Cell RNA - hTERT-RPE1 [nTPM]":"84.2","Cell RNA - HUVEC TERT2 [nTPM]":"37.4","Cell RNA - JURKAT [nTPM]":"38.3","Cell RNA - K-562 [nTPM]":"71.1","Cell RNA - Karpas-707 [nTPM]":"35.7","Cell RNA - LHCN-M2 [nTPM]":"50.3","Cell RNA - MCF7 [nTPM]":"31.0","Cell RNA - MOLT-4 [nTPM]":"22.3","Cell RNA - NB-4 [nTPM]":"42.0","Cell RNA - NTERA-2 [nTPM]":"9.9","Cell RNA - OE19 [nTPM]":"15.5","Cell RNA - PC-3 [nTPM]":"37.6","Cell RNA - REH [nTPM]":"12.2","Cell RNA - RH-30 [nTPM]":"19.3","Cell RNA - RPMI-8226 [nTPM]":"123.4","Cell RNA - RPTEC TERT1 [nTPM]":"77.0","Cell RNA - RT4 [nTPM]":"25.2","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"8.3","Cell RNA - SiHa [nTPM]":"27.4","Cell RNA - SK-BR-3 [nTPM]":"76.7","Cell RNA - SK-MEL-30 [nTPM]":"77.9","Cell RNA - SuSa [nTPM]":"21.6","Cell RNA - T-47d [nTPM]":"58.3","Cell RNA - THP-1 [nTPM]":"55.0","Cell RNA - TIME [nTPM]":"126.1","Cell RNA - U-138 MG [nTPM]":"46.8","Cell RNA - U-2 OS [nTPM]":"30.0","Cell RNA - U-2197 [nTPM]":"25.5","Cell RNA - U-251 MG [nTPM]":"42.7","Cell RNA - U-266\/70 [nTPM]":"32.7","Cell RNA - U-266\/84 [nTPM]":"69.5","Cell RNA - U-698 [nTPM]":"13.8","Cell RNA - U-87 MG [nTPM]":"99.6","Cell RNA - U-937 [nTPM]":"187.5","Cell RNA - WM-115 [nTPM]":"26.9","Blood RNA - basophil [nTPM]":"34.5","Blood RNA - classical monocyte [nTPM]":"18.8","Blood RNA - eosinophil [nTPM]":"3.3","Blood RNA - gdT-cell [nTPM]":"9.6","Blood RNA - intermediate monocyte [nTPM]":"8.1","Blood RNA - MAIT T-cell [nTPM]":"2.3","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"2.4","Blood RNA - memory CD8 T-cell [nTPM]":"6.0","Blood RNA - myeloid DC [nTPM]":"25.3","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"3.1","Blood RNA - naive CD8 T-cell [nTPM]":"2.7","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"5.7","Blood RNA - non-classical monocyte [nTPM]":"8.4","Blood RNA - plasmacytoid DC [nTPM]":"1.9","Blood RNA - T-reg [nTPM]":"2.5","Blood RNA - total PBMC [nTPM]":"9.7","Brain RNA - amygdala [nTPM]":"16.0","Brain RNA - basal ganglia [nTPM]":"17.1","Brain RNA - cerebellum [nTPM]":"16.6","Brain RNA - cerebral cortex [nTPM]":"21.1","Brain RNA - hippocampal formation [nTPM]":"16.3","Brain RNA - hypothalamus [nTPM]":"18.8","Brain RNA - medulla oblongata [nTPM]":"17.9","Brain RNA - midbrain [nTPM]":"19.6","Brain RNA - pons [nTPM]":"16.9","Brain RNA - spinal cord [nTPM]":"17.2","Brain RNA - thalamus [nTPM]":"17.4","Brain RNA - white matter [nTPM]":"17.5","Single Cell Type RNA - Adipocytes [nTPM]":"3.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.8","Single Cell Type RNA - Astrocytes [nTPM]":"9.8","Single Cell Type RNA - B-cells [nTPM]":"4.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"12.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"37.9","Single Cell Type RNA - dendritic cells [nTPM]":"4.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"52.8","Single Cell Type RNA - Ductal cells [nTPM]":"9.3","Single Cell Type RNA - Early spermatids [nTPM]":"7.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.2","Single Cell Type RNA - Endothelial cells [nTPM]":"3.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"24.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.1","Single Cell Type RNA - Fibroblasts [nTPM]":"16.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.0","Single Cell Type RNA - granulocytes [nTPM]":"41.9","Single Cell Type RNA - Granulosa cells [nTPM]":"6.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.9","Single Cell Type RNA - Hepatocytes [nTPM]":"266.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"72.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.0","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"21.4","Single Cell Type RNA - Langerhans cells [nTPM]":"6.6","Single Cell Type RNA - Late spermatids [nTPM]":"13.5","Single Cell Type RNA - Leydig cells [nTPM]":"9.9","Single Cell Type RNA - Macrophages [nTPM]":"30.5","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"5.7","Single Cell Type RNA - Muller glia cells [nTPM]":"7.3","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.5","Single Cell Type RNA - Paneth cells [nTPM]":"12.8","Single Cell Type RNA - Peritubular cells [nTPM]":"7.9","Single Cell Type RNA - Plasma cells [nTPM]":"5.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"54.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"305.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.2","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"2.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.0","Single Cell Type RNA - T-cells [nTPM]":"7.7","Single Cell Type RNA - Theca cells [nTPM]":"8.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"22.4","Single Cell Type RNA - Urothelial cells [nTPM]":"16.4"},{"Gene":"FAM20C","Gene synonym":["DKFZp547D065","DMP4","G-CK","IMAGE:4942737"],"Ensembl":"ENSG00000177706","Gene description":"FAM20C golgi associated secretory pathway kinase","Uniprot":["Q8IXL6"],"Chromosome":"7","Position":"192571-260772","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted secreted proteins"],"Biological process":["Biomineralization"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"55.2","Hepatocytes":"94.0","Hofbauer cells":"54.9","Peritubular cells":"56.4","Proximal tubular cells":"48.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HSkMC":"55.3","hTERT-RPE1":"39.9","U-87 MG":"36.0","WM-115":"30.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019823"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"240000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA019823":"AB_1848389"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.89e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.40e-6"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-3"},"Tissue RNA - adipose tissue [nTPM]":"32.5","Tissue RNA - adrenal gland [nTPM]":"14.8","Tissue RNA - amygdala [nTPM]":"7.0","Tissue RNA - appendix [nTPM]":"7.3","Tissue RNA - basal ganglia [nTPM]":"5.7","Tissue RNA - bone marrow [nTPM]":"1.5","Tissue RNA - breast [nTPM]":"32.8","Tissue RNA - cerebellum [nTPM]":"5.0","Tissue RNA - cerebral cortex [nTPM]":"7.0","Tissue RNA - cervix [nTPM]":"19.4","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"44.3","Tissue RNA - duodenum [nTPM]":"4.5","Tissue RNA - endometrium 1 [nTPM]":"19.4","Tissue RNA - epididymis [nTPM]":"2.1","Tissue RNA - esophagus [nTPM]":"14.3","Tissue RNA - fallopian tube [nTPM]":"20.2","Tissue RNA - gallbladder [nTPM]":"5.9","Tissue RNA - heart muscle [nTPM]":"30.2","Tissue RNA - hippocampal formation [nTPM]":"4.3","Tissue RNA - hypothalamus [nTPM]":"5.0","Tissue RNA - kidney [nTPM]":"34.9","Tissue RNA - liver [nTPM]":"56.5","Tissue RNA - lung [nTPM]":"27.9","Tissue RNA - lymph node [nTPM]":"1.1","Tissue RNA - medulla oblongata [nTPM]":"12.5","Tissue RNA - midbrain [nTPM]":"9.7","Tissue RNA - ovary [nTPM]":"20.3","Tissue RNA - pancreas [nTPM]":"13.4","Tissue RNA - parathyroid gland [nTPM]":"1.6","Tissue RNA - pituitary gland [nTPM]":"18.3","Tissue RNA - placenta [nTPM]":"2.6","Tissue RNA - pons [nTPM]":"6.7","Tissue RNA - prostate [nTPM]":"29.9","Tissue RNA - rectum [nTPM]":"1.4","Tissue RNA - retina [nTPM]":"1.1","Tissue RNA - salivary gland [nTPM]":"20.3","Tissue RNA - seminal vesicle [nTPM]":"3.6","Tissue RNA - skeletal muscle [nTPM]":"30.7","Tissue RNA - skin 1 [nTPM]":"14.7","Tissue RNA - small intestine [nTPM]":"23.3","Tissue RNA - smooth muscle [nTPM]":"6.8","Tissue RNA - spinal cord [nTPM]":"6.4","Tissue RNA - spleen [nTPM]":"8.9","Tissue RNA - stomach 1 [nTPM]":"38.9","Tissue RNA - testis [nTPM]":"7.8","Tissue RNA - thalamus [nTPM]":"12.6","Tissue RNA - thymus [nTPM]":"0.6","Tissue RNA - thyroid gland [nTPM]":"19.6","Tissue RNA - tongue [nTPM]":"6.3","Tissue RNA - tonsil [nTPM]":"0.6","Tissue RNA - urinary bladder [nTPM]":"36.8","Tissue RNA - vagina [nTPM]":"15.1","Tissue RNA - white matter [nTPM]":"6.2","Cell RNA - A-431 [nTPM]":"19.6","Cell RNA - A549 [nTPM]":"6.4","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"10.3","Cell RNA - ASC diff [nTPM]":"11.8","Cell RNA - ASC TERT1 [nTPM]":"20.3","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"17.4","Cell RNA - BJ hTERT+ [nTPM]":"23.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.9","Cell RNA - CACO-2 [nTPM]":"0.9","Cell RNA - CAPAN-2 [nTPM]":"10.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"9.3","Cell RNA - fHDF\/TERT166 [nTPM]":"21.8","Cell RNA - GAMG [nTPM]":"10.4","Cell RNA - HaCaT [nTPM]":"14.9","Cell RNA - HAP1 [nTPM]":"1.1","Cell RNA - HBEC3-KT [nTPM]":"0.6","Cell RNA - HBF TERT88 [nTPM]":"1.6","Cell RNA - HDLM-2 [nTPM]":"4.5","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"3.1","Cell RNA - Hep G2 [nTPM]":"3.4","Cell RNA - HHSteC [nTPM]":"8.8","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.0","Cell RNA - HSkMC [nTPM]":"55.3","Cell RNA - hTCEpi [nTPM]":"1.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.3","Cell RNA - hTERT-HME1 [nTPM]":"0.7","Cell RNA - hTERT-RPE1 [nTPM]":"39.9","Cell RNA - HUVEC TERT2 [nTPM]":"5.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"1.8","Cell RNA - MCF7 [nTPM]":"1.9","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.7","Cell RNA - NTERA-2 [nTPM]":"8.9","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"2.3","Cell RNA - RH-30 [nTPM]":"0.5","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"4.9","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"4.4","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"17.2","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"2.3","Cell RNA - SuSa [nTPM]":"1.1","Cell RNA - T-47d [nTPM]":"9.7","Cell RNA - THP-1 [nTPM]":"6.5","Cell RNA - TIME [nTPM]":"14.6","Cell RNA - U-138 MG [nTPM]":"10.3","Cell RNA - U-2 OS [nTPM]":"5.3","Cell RNA - U-2197 [nTPM]":"7.7","Cell RNA - U-251 MG [nTPM]":"5.3","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"36.0","Cell RNA - U-937 [nTPM]":"1.0","Cell RNA - WM-115 [nTPM]":"30.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"7.0","Brain RNA - basal ganglia [nTPM]":"5.7","Brain RNA - cerebellum [nTPM]":"5.0","Brain RNA - cerebral cortex [nTPM]":"7.0","Brain RNA - hippocampal formation [nTPM]":"4.3","Brain RNA - hypothalamus [nTPM]":"5.0","Brain RNA - medulla oblongata [nTPM]":"12.5","Brain RNA - midbrain [nTPM]":"9.7","Brain RNA - pons [nTPM]":"6.7","Brain RNA - spinal cord [nTPM]":"6.4","Brain RNA - thalamus [nTPM]":"12.6","Brain RNA - white matter [nTPM]":"6.2","Single Cell Type RNA - Adipocytes [nTPM]":"5.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.1","Single Cell Type RNA - Astrocytes [nTPM]":"11.8","Single Cell Type RNA - B-cells [nTPM]":"1.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"26.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"27.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"1.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"55.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"4.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.0","Single Cell Type RNA - Endothelial cells [nTPM]":"4.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.9","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"22.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.5","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"3.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.3","Single Cell Type RNA - Hepatocytes [nTPM]":"94.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"54.9","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.3","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"24.4","Single Cell Type RNA - Langerhans cells [nTPM]":"9.8","Single Cell Type RNA - Late spermatids [nTPM]":"2.6","Single Cell Type RNA - Leydig cells [nTPM]":"16.1","Single Cell Type RNA - Macrophages [nTPM]":"34.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"10.8","Single Cell Type RNA - Muller glia cells [nTPM]":"17.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.3","Single Cell Type RNA - Paneth cells [nTPM]":"3.7","Single Cell Type RNA - Peritubular cells [nTPM]":"56.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"33.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"48.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"0.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.9"},{"Gene":"FAN1","Gene synonym":["KIAA1018","MTMR15"],"Ensembl":"ENSG00000198690","Gene description":"FANCD2 and FANCI associated nuclease 1","Uniprot":["Q9Y2M0"],"Chromosome":"15","Position":"30890559-30943108","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["Endonuclease","Exonuclease","Hydrolase","Nuclease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"44.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048198"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytokinetic bridge","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytokinetic bridge","Cytosol"],"Antibody RRID":{"HPA048198":"AB_2680311"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.42e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.2","Tissue RNA - adrenal gland [nTPM]":"8.5","Tissue RNA - amygdala [nTPM]":"9.3","Tissue RNA - appendix [nTPM]":"0.9","Tissue RNA - basal ganglia [nTPM]":"9.5","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"6.7","Tissue RNA - cerebellum [nTPM]":"9.4","Tissue RNA - cerebral cortex [nTPM]":"9.7","Tissue RNA - cervix [nTPM]":"10.1","Tissue RNA - choroid plexus [nTPM]":"9.3","Tissue RNA - colon [nTPM]":"10.7","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"9.2","Tissue RNA - epididymis [nTPM]":"6.6","Tissue RNA - esophagus [nTPM]":"6.5","Tissue RNA - fallopian tube [nTPM]":"9.0","Tissue RNA - gallbladder [nTPM]":"1.2","Tissue RNA - heart muscle [nTPM]":"8.8","Tissue RNA - hippocampal formation [nTPM]":"8.9","Tissue RNA - hypothalamus [nTPM]":"9.5","Tissue RNA - kidney [nTPM]":"9.5","Tissue RNA - liver [nTPM]":"9.6","Tissue RNA - lung [nTPM]":"5.5","Tissue RNA - lymph node [nTPM]":"0.8","Tissue RNA - medulla oblongata [nTPM]":"9.7","Tissue RNA - midbrain [nTPM]":"9.8","Tissue RNA - ovary [nTPM]":"11.8","Tissue RNA - pancreas [nTPM]":"12.7","Tissue RNA - parathyroid gland [nTPM]":"5.9","Tissue RNA - pituitary gland [nTPM]":"11.4","Tissue RNA - placenta [nTPM]":"3.0","Tissue RNA - pons [nTPM]":"10.0","Tissue RNA - prostate [nTPM]":"11.5","Tissue RNA - rectum [nTPM]":"2.0","Tissue RNA - retina [nTPM]":"2.7","Tissue RNA - salivary gland [nTPM]":"9.8","Tissue RNA - seminal vesicle [nTPM]":"1.4","Tissue RNA - skeletal muscle [nTPM]":"18.7","Tissue RNA - skin 1 [nTPM]":"10.8","Tissue RNA - small intestine [nTPM]":"7.3","Tissue RNA - smooth muscle [nTPM]":"2.4","Tissue RNA - spinal cord [nTPM]":"9.5","Tissue RNA - spleen [nTPM]":"6.8","Tissue RNA - stomach 1 [nTPM]":"8.6","Tissue RNA - testis [nTPM]":"8.9","Tissue RNA - thalamus [nTPM]":"9.9","Tissue RNA - thymus [nTPM]":"4.4","Tissue RNA - thyroid gland [nTPM]":"10.0","Tissue RNA - tongue [nTPM]":"7.3","Tissue RNA - tonsil [nTPM]":"0.7","Tissue RNA - urinary bladder [nTPM]":"9.3","Tissue RNA - vagina [nTPM]":"9.7","Tissue RNA - white matter [nTPM]":"10.0","Cell RNA - A-431 [nTPM]":"5.2","Cell RNA - A549 [nTPM]":"9.9","Cell RNA - AF22 [nTPM]":"3.6","Cell RNA - AN3-CA [nTPM]":"1.9","Cell RNA - ASC diff [nTPM]":"12.4","Cell RNA - ASC TERT1 [nTPM]":"9.3","Cell RNA - BEWO [nTPM]":"0.8","Cell RNA - BJ [nTPM]":"4.4","Cell RNA - BJ hTERT+ [nTPM]":"2.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.0","Cell RNA - CACO-2 [nTPM]":"4.5","Cell RNA - CAPAN-2 [nTPM]":"1.7","Cell RNA - Daudi [nTPM]":"0.6","Cell RNA - EFO-21 [nTPM]":"7.6","Cell RNA - fHDF\/TERT166 [nTPM]":"3.6","Cell RNA - GAMG [nTPM]":"7.4","Cell RNA - HaCaT [nTPM]":"9.2","Cell RNA - HAP1 [nTPM]":"4.7","Cell RNA - HBEC3-KT [nTPM]":"9.4","Cell RNA - HBF TERT88 [nTPM]":"5.0","Cell RNA - HDLM-2 [nTPM]":"4.2","Cell RNA - HEK 293 [nTPM]":"1.4","Cell RNA - HEL [nTPM]":"1.3","Cell RNA - HeLa [nTPM]":"5.5","Cell RNA - Hep G2 [nTPM]":"1.9","Cell RNA - HHSteC [nTPM]":"4.8","Cell RNA - HL-60 [nTPM]":"1.2","Cell RNA - HMC-1 [nTPM]":"1.9","Cell RNA - HSkMC [nTPM]":"2.8","Cell RNA - hTCEpi [nTPM]":"7.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.0","Cell RNA - hTERT-HME1 [nTPM]":"7.3","Cell RNA - hTERT-RPE1 [nTPM]":"7.2","Cell RNA - HUVEC TERT2 [nTPM]":"3.4","Cell RNA - JURKAT [nTPM]":"5.7","Cell RNA - K-562 [nTPM]":"4.7","Cell RNA - Karpas-707 [nTPM]":"6.1","Cell RNA - LHCN-M2 [nTPM]":"4.7","Cell RNA - MCF7 [nTPM]":"0.6","Cell RNA - MOLT-4 [nTPM]":"8.6","Cell RNA - NB-4 [nTPM]":"3.1","Cell RNA - NTERA-2 [nTPM]":"2.2","Cell RNA - OE19 [nTPM]":"11.5","Cell RNA - PC-3 [nTPM]":"2.8","Cell RNA - REH [nTPM]":"7.0","Cell RNA - RH-30 [nTPM]":"12.0","Cell RNA - RPMI-8226 [nTPM]":"2.3","Cell RNA - RPTEC TERT1 [nTPM]":"6.7","Cell RNA - RT4 [nTPM]":"2.3","Cell RNA - SCLC-21H [nTPM]":"4.5","Cell RNA - SH-SY5Y [nTPM]":"4.6","Cell RNA - SiHa [nTPM]":"9.2","Cell RNA - SK-BR-3 [nTPM]":"5.6","Cell RNA - SK-MEL-30 [nTPM]":"3.0","Cell RNA - SuSa [nTPM]":"8.8","Cell RNA - T-47d [nTPM]":"4.4","Cell RNA - THP-1 [nTPM]":"3.3","Cell RNA - TIME [nTPM]":"3.3","Cell RNA - U-138 MG [nTPM]":"9.4","Cell RNA - U-2 OS [nTPM]":"3.0","Cell RNA - U-2197 [nTPM]":"5.0","Cell RNA - U-251 MG [nTPM]":"3.4","Cell RNA - U-266\/70 [nTPM]":"7.4","Cell RNA - U-266\/84 [nTPM]":"8.7","Cell RNA - U-698 [nTPM]":"1.1","Cell RNA - U-87 MG [nTPM]":"4.1","Cell RNA - U-937 [nTPM]":"1.9","Cell RNA - WM-115 [nTPM]":"1.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.4","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"2.0","Blood RNA - memory B-cell [nTPM]":"1.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"0.9","Blood RNA - naive B-cell [nTPM]":"1.5","Blood RNA - naive CD4 T-cell [nTPM]":"1.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"4.3","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"1.4","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"9.3","Brain RNA - basal ganglia [nTPM]":"9.5","Brain RNA - cerebellum [nTPM]":"9.4","Brain RNA - cerebral cortex [nTPM]":"9.7","Brain RNA - hippocampal formation [nTPM]":"8.9","Brain RNA - hypothalamus [nTPM]":"9.5","Brain RNA - medulla oblongata [nTPM]":"9.7","Brain RNA - midbrain [nTPM]":"9.8","Brain RNA - pons [nTPM]":"10.0","Brain RNA - spinal cord [nTPM]":"9.5","Brain RNA - thalamus [nTPM]":"9.9","Brain RNA - white matter [nTPM]":"10.0","Single Cell Type RNA - Adipocytes [nTPM]":"9.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.4","Single Cell Type RNA - Astrocytes [nTPM]":"21.2","Single Cell Type RNA - B-cells [nTPM]":"5.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"17.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"10.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.5","Single Cell Type RNA - dendritic cells [nTPM]":"3.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"4.5","Single Cell Type RNA - Early spermatids [nTPM]":"11.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.9","Single Cell Type RNA - Endothelial cells [nTPM]":"8.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.8","Single Cell Type RNA - Erythroid cells [nTPM]":"6.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.2","Single Cell Type RNA - Fibroblasts [nTPM]":"8.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.0","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"15.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"13.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.7","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.0","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.4","Single Cell Type RNA - Langerhans cells [nTPM]":"2.5","Single Cell Type RNA - Late spermatids [nTPM]":"7.1","Single Cell Type RNA - Leydig cells [nTPM]":"10.5","Single Cell Type RNA - Macrophages [nTPM]":"3.9","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"3.4","Single Cell Type RNA - Muller glia cells [nTPM]":"14.9","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"44.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.6","Single Cell Type RNA - Paneth cells [nTPM]":"6.4","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"7.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.6","Single Cell Type RNA - Spermatocytes [nTPM]":"20.9","Single Cell Type RNA - Spermatogonia [nTPM]":"16.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.1","Single Cell Type RNA - T-cells [nTPM]":"5.3","Single Cell Type RNA - Theca cells [nTPM]":"9.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.3","Single Cell Type RNA - Urothelial cells [nTPM]":"3.7"},{"Gene":"FANCL","Gene synonym":["FAAP43","FLJ10335","PHF9","Pog"],"Ensembl":"ENSG00000115392","Gene description":"FA complementation group L","Uniprot":["Q9NW38"],"Chromosome":"2","Position":"58159243-58241372","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Fanconi anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"81.4","Oligodendrocytes":"188.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033842","HPA036685","HPA036686"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB033842":"AB_1122766","HPA036685":"AB_10672474","HPA036686":"AB_10670844"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.81e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.12e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.08e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.80e-5"},"Tissue RNA - adipose tissue [nTPM]":"8.5","Tissue RNA - adrenal gland [nTPM]":"35.3","Tissue RNA - amygdala [nTPM]":"39.4","Tissue RNA - appendix [nTPM]":"11.0","Tissue RNA - basal ganglia [nTPM]":"49.5","Tissue RNA - bone marrow [nTPM]":"15.1","Tissue RNA - breast [nTPM]":"19.5","Tissue RNA - cerebellum [nTPM]":"35.3","Tissue RNA - cerebral cortex [nTPM]":"39.4","Tissue RNA - cervix [nTPM]":"18.6","Tissue RNA - choroid plexus [nTPM]":"27.2","Tissue RNA - colon [nTPM]":"12.1","Tissue RNA - duodenum [nTPM]":"11.5","Tissue RNA - endometrium 1 [nTPM]":"19.9","Tissue RNA - epididymis [nTPM]":"18.4","Tissue RNA - esophagus [nTPM]":"11.5","Tissue RNA - fallopian tube [nTPM]":"13.9","Tissue RNA - gallbladder [nTPM]":"12.0","Tissue RNA - heart muscle [nTPM]":"13.0","Tissue RNA - hippocampal formation [nTPM]":"34.1","Tissue RNA - hypothalamus [nTPM]":"45.1","Tissue RNA - kidney [nTPM]":"12.2","Tissue RNA - liver [nTPM]":"21.7","Tissue RNA - lung [nTPM]":"9.6","Tissue RNA - lymph node [nTPM]":"14.8","Tissue RNA - medulla oblongata [nTPM]":"51.6","Tissue RNA - midbrain [nTPM]":"40.3","Tissue RNA - ovary [nTPM]":"24.8","Tissue RNA - pancreas [nTPM]":"14.5","Tissue RNA - parathyroid gland [nTPM]":"14.0","Tissue RNA - pituitary gland [nTPM]":"44.3","Tissue RNA - placenta [nTPM]":"12.5","Tissue RNA - pons [nTPM]":"55.4","Tissue RNA - prostate [nTPM]":"14.7","Tissue RNA - rectum [nTPM]":"14.8","Tissue RNA - retina [nTPM]":"24.6","Tissue RNA - salivary gland [nTPM]":"18.7","Tissue RNA - seminal vesicle [nTPM]":"10.7","Tissue RNA - skeletal muscle [nTPM]":"9.1","Tissue RNA - skin 1 [nTPM]":"17.9","Tissue RNA - small intestine [nTPM]":"12.8","Tissue RNA - smooth muscle [nTPM]":"13.5","Tissue RNA - spinal cord [nTPM]":"40.9","Tissue RNA - spleen [nTPM]":"16.8","Tissue RNA - stomach 1 [nTPM]":"13.1","Tissue RNA - testis [nTPM]":"19.1","Tissue RNA - thalamus [nTPM]":"41.2","Tissue RNA - thymus [nTPM]":"13.2","Tissue RNA - thyroid gland [nTPM]":"17.1","Tissue RNA - tongue [nTPM]":"9.1","Tissue RNA - tonsil [nTPM]":"12.6","Tissue RNA - urinary bladder [nTPM]":"11.7","Tissue RNA - vagina [nTPM]":"14.6","Tissue RNA - white matter [nTPM]":"68.6","Cell RNA - A-431 [nTPM]":"48.6","Cell RNA - A549 [nTPM]":"35.0","Cell RNA - AF22 [nTPM]":"69.4","Cell RNA - AN3-CA [nTPM]":"34.0","Cell RNA - ASC diff [nTPM]":"11.9","Cell RNA - ASC TERT1 [nTPM]":"15.1","Cell RNA - BEWO [nTPM]":"36.9","Cell RNA - BJ [nTPM]":"34.8","Cell RNA - BJ hTERT+ [nTPM]":"21.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"33.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"43.5","Cell RNA - CACO-2 [nTPM]":"30.9","Cell RNA - CAPAN-2 [nTPM]":"59.4","Cell RNA - Daudi [nTPM]":"33.4","Cell RNA - EFO-21 [nTPM]":"43.8","Cell RNA - fHDF\/TERT166 [nTPM]":"11.4","Cell RNA - GAMG [nTPM]":"46.3","Cell RNA - HaCaT [nTPM]":"27.5","Cell RNA - HAP1 [nTPM]":"39.0","Cell RNA - HBEC3-KT [nTPM]":"26.4","Cell RNA - HBF TERT88 [nTPM]":"56.0","Cell RNA - HDLM-2 [nTPM]":"78.8","Cell RNA - HEK 293 [nTPM]":"61.7","Cell RNA - HEL [nTPM]":"54.8","Cell RNA - HeLa [nTPM]":"49.5","Cell RNA - Hep G2 [nTPM]":"42.1","Cell RNA - HHSteC [nTPM]":"13.0","Cell RNA - HL-60 [nTPM]":"53.3","Cell RNA - HMC-1 [nTPM]":"29.0","Cell RNA - HSkMC [nTPM]":"11.8","Cell RNA - hTCEpi [nTPM]":"12.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"24.8","Cell RNA - hTERT-HME1 [nTPM]":"9.7","Cell RNA - hTERT-RPE1 [nTPM]":"29.9","Cell RNA - HUVEC TERT2 [nTPM]":"27.0","Cell RNA - JURKAT [nTPM]":"23.5","Cell RNA - K-562 [nTPM]":"51.9","Cell RNA - Karpas-707 [nTPM]":"29.6","Cell RNA - LHCN-M2 [nTPM]":"23.2","Cell RNA - MCF7 [nTPM]":"24.6","Cell RNA - MOLT-4 [nTPM]":"18.9","Cell RNA - NB-4 [nTPM]":"65.8","Cell RNA - NTERA-2 [nTPM]":"75.2","Cell RNA - OE19 [nTPM]":"77.4","Cell RNA - PC-3 [nTPM]":"7.2","Cell RNA - REH [nTPM]":"35.2","Cell RNA - RH-30 [nTPM]":"52.5","Cell RNA - RPMI-8226 [nTPM]":"26.1","Cell RNA - RPTEC TERT1 [nTPM]":"29.9","Cell RNA - RT4 [nTPM]":"47.2","Cell RNA - SCLC-21H [nTPM]":"78.1","Cell RNA - SH-SY5Y [nTPM]":"39.3","Cell RNA - SiHa [nTPM]":"49.5","Cell RNA - SK-BR-3 [nTPM]":"20.2","Cell RNA - SK-MEL-30 [nTPM]":"33.8","Cell RNA - SuSa [nTPM]":"37.0","Cell RNA - T-47d [nTPM]":"18.7","Cell RNA - THP-1 [nTPM]":"35.4","Cell RNA - TIME [nTPM]":"15.9","Cell RNA - U-138 MG [nTPM]":"30.0","Cell RNA - U-2 OS [nTPM]":"45.0","Cell RNA - U-2197 [nTPM]":"22.3","Cell RNA - U-251 MG [nTPM]":"39.0","Cell RNA - U-266\/70 [nTPM]":"30.4","Cell RNA - U-266\/84 [nTPM]":"20.6","Cell RNA - U-698 [nTPM]":"19.7","Cell RNA - U-87 MG [nTPM]":"63.7","Cell RNA - U-937 [nTPM]":"35.7","Cell RNA - WM-115 [nTPM]":"46.6","Blood RNA - basophil [nTPM]":"3.2","Blood RNA - classical monocyte [nTPM]":"3.0","Blood RNA - eosinophil [nTPM]":"4.9","Blood RNA - gdT-cell [nTPM]":"3.7","Blood RNA - intermediate monocyte [nTPM]":"5.6","Blood RNA - MAIT T-cell [nTPM]":"3.0","Blood RNA - memory B-cell [nTPM]":"9.1","Blood RNA - memory CD4 T-cell [nTPM]":"3.2","Blood RNA - memory CD8 T-cell [nTPM]":"4.2","Blood RNA - myeloid DC [nTPM]":"5.9","Blood RNA - naive B-cell [nTPM]":"9.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"2.3","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"7.6","Blood RNA - non-classical monocyte [nTPM]":"4.3","Blood RNA - plasmacytoid DC [nTPM]":"5.3","Blood RNA - T-reg [nTPM]":"4.8","Blood RNA - total PBMC [nTPM]":"2.2","Brain RNA - amygdala [nTPM]":"39.4","Brain RNA - basal ganglia [nTPM]":"49.5","Brain RNA - cerebellum [nTPM]":"35.3","Brain RNA - cerebral cortex [nTPM]":"39.4","Brain RNA - hippocampal formation [nTPM]":"34.1","Brain RNA - hypothalamus [nTPM]":"45.1","Brain RNA - medulla oblongata [nTPM]":"51.6","Brain RNA - midbrain [nTPM]":"40.3","Brain RNA - pons [nTPM]":"55.4","Brain RNA - spinal cord [nTPM]":"40.9","Brain RNA - thalamus [nTPM]":"41.2","Brain RNA - white matter [nTPM]":"68.6","Single Cell Type RNA - Adipocytes [nTPM]":"16.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.0","Single Cell Type RNA - Astrocytes [nTPM]":"18.6","Single Cell Type RNA - B-cells [nTPM]":"9.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"26.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"16.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"16.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"29.1","Single Cell Type RNA - dendritic cells [nTPM]":"4.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"9.7","Single Cell Type RNA - Early spermatids [nTPM]":"2.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.8","Single Cell Type RNA - Endothelial cells [nTPM]":"14.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.0","Single Cell Type RNA - Erythroid cells [nTPM]":"14.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"45.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.0","Single Cell Type RNA - Fibroblasts [nTPM]":"12.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.2","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"25.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.2","Single Cell Type RNA - Hepatocytes [nTPM]":"12.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.9","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"38.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.0","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"6.3","Single Cell Type RNA - Langerhans cells [nTPM]":"4.6","Single Cell Type RNA - Late spermatids [nTPM]":"3.6","Single Cell Type RNA - Leydig cells [nTPM]":"10.8","Single Cell Type RNA - Macrophages [nTPM]":"7.0","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"34.7","Single Cell Type RNA - monocytes [nTPM]":"6.8","Single Cell Type RNA - Muller glia cells [nTPM]":"22.8","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"81.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"188.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.6","Single Cell Type RNA - Paneth cells [nTPM]":"13.3","Single Cell Type RNA - Peritubular cells [nTPM]":"14.3","Single Cell Type RNA - Plasma cells [nTPM]":"9.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"21.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.4","Single Cell Type RNA - Spermatocytes [nTPM]":"52.6","Single Cell Type RNA - Spermatogonia [nTPM]":"37.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.4","Single Cell Type RNA - T-cells [nTPM]":"5.6","Single Cell Type RNA - Theca cells [nTPM]":"13.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.0","Single Cell Type RNA - Urothelial cells [nTPM]":"9.3"},{"Gene":"FANCM","Gene synonym":["FAAP250","KIAA1596"],"Ensembl":"ENSG00000187790","Gene description":"FA complementation group M","Uniprot":["Q8IYD8"],"Chromosome":"14","Position":"45135930-45200890","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Disease variant","Premature ovarian failure"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"65.5","Late spermatids":"206.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055144"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA055144":"AB_2682715"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.9","Tissue RNA - adrenal gland [nTPM]":"1.6","Tissue RNA - amygdala [nTPM]":"0.8","Tissue RNA - appendix [nTPM]":"2.2","Tissue RNA - basal ganglia [nTPM]":"1.6","Tissue RNA - bone marrow [nTPM]":"5.6","Tissue RNA - breast [nTPM]":"2.8","Tissue RNA - cerebellum [nTPM]":"1.9","Tissue RNA - cerebral cortex [nTPM]":"2.2","Tissue RNA - cervix [nTPM]":"2.0","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"1.6","Tissue RNA - duodenum [nTPM]":"1.3","Tissue RNA - endometrium 1 [nTPM]":"2.4","Tissue RNA - epididymis [nTPM]":"2.2","Tissue RNA - esophagus [nTPM]":"1.9","Tissue RNA - fallopian tube [nTPM]":"1.6","Tissue RNA - gallbladder [nTPM]":"1.8","Tissue RNA - heart muscle [nTPM]":"1.3","Tissue RNA - hippocampal formation [nTPM]":"1.0","Tissue RNA - hypothalamus [nTPM]":"0.9","Tissue RNA - kidney [nTPM]":"1.8","Tissue RNA - liver [nTPM]":"1.5","Tissue RNA - lung [nTPM]":"1.7","Tissue RNA - lymph node [nTPM]":"3.3","Tissue RNA - medulla oblongata [nTPM]":"1.0","Tissue RNA - midbrain [nTPM]":"0.8","Tissue RNA - ovary [nTPM]":"2.9","Tissue RNA - pancreas [nTPM]":"1.1","Tissue RNA - parathyroid gland [nTPM]":"1.5","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"1.9","Tissue RNA - pons [nTPM]":"1.2","Tissue RNA - prostate [nTPM]":"1.6","Tissue RNA - rectum [nTPM]":"1.8","Tissue RNA - retina [nTPM]":"2.8","Tissue RNA - salivary gland [nTPM]":"1.4","Tissue RNA - seminal vesicle [nTPM]":"1.9","Tissue RNA - skeletal muscle [nTPM]":"1.6","Tissue RNA - skin 1 [nTPM]":"2.6","Tissue RNA - small intestine [nTPM]":"1.2","Tissue RNA - smooth muscle [nTPM]":"1.9","Tissue RNA - spinal cord [nTPM]":"0.7","Tissue RNA - spleen [nTPM]":"2.3","Tissue RNA - stomach 1 [nTPM]":"1.4","Tissue RNA - testis [nTPM]":"7.6","Tissue RNA - thalamus [nTPM]":"1.1","Tissue RNA - thymus [nTPM]":"4.1","Tissue RNA - thyroid gland [nTPM]":"1.5","Tissue RNA - tongue [nTPM]":"2.3","Tissue RNA - tonsil [nTPM]":"2.6","Tissue RNA - urinary bladder [nTPM]":"1.5","Tissue RNA - vagina [nTPM]":"1.5","Tissue RNA - white matter [nTPM]":"1.2","Cell RNA - A-431 [nTPM]":"8.2","Cell RNA - A549 [nTPM]":"7.0","Cell RNA - AF22 [nTPM]":"8.1","Cell RNA - AN3-CA [nTPM]":"7.5","Cell RNA - ASC diff [nTPM]":"6.4","Cell RNA - ASC TERT1 [nTPM]":"3.5","Cell RNA - BEWO [nTPM]":"6.5","Cell RNA - BJ [nTPM]":"10.3","Cell RNA - BJ hTERT+ [nTPM]":"4.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.1","Cell RNA - CACO-2 [nTPM]":"11.3","Cell RNA - CAPAN-2 [nTPM]":"6.2","Cell RNA - Daudi [nTPM]":"10.6","Cell RNA - EFO-21 [nTPM]":"5.8","Cell RNA - fHDF\/TERT166 [nTPM]":"2.6","Cell RNA - GAMG [nTPM]":"4.5","Cell RNA - HaCaT [nTPM]":"10.6","Cell RNA - HAP1 [nTPM]":"9.5","Cell RNA - HBEC3-KT [nTPM]":"4.4","Cell RNA - HBF TERT88 [nTPM]":"11.0","Cell RNA - HDLM-2 [nTPM]":"7.6","Cell RNA - HEK 293 [nTPM]":"5.4","Cell RNA - HEL [nTPM]":"5.1","Cell RNA - HeLa [nTPM]":"7.8","Cell RNA - Hep G2 [nTPM]":"6.4","Cell RNA - HHSteC [nTPM]":"1.1","Cell RNA - HL-60 [nTPM]":"13.0","Cell RNA - HMC-1 [nTPM]":"6.1","Cell RNA - HSkMC [nTPM]":"2.2","Cell RNA - hTCEpi [nTPM]":"1.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.1","Cell RNA - hTERT-HME1 [nTPM]":"5.1","Cell RNA - hTERT-RPE1 [nTPM]":"1.8","Cell RNA - HUVEC TERT2 [nTPM]":"7.1","Cell RNA - JURKAT [nTPM]":"6.6","Cell RNA - K-562 [nTPM]":"9.1","Cell RNA - Karpas-707 [nTPM]":"8.9","Cell RNA - LHCN-M2 [nTPM]":"6.9","Cell RNA - MCF7 [nTPM]":"8.1","Cell RNA - MOLT-4 [nTPM]":"9.5","Cell RNA - NB-4 [nTPM]":"9.2","Cell RNA - NTERA-2 [nTPM]":"3.2","Cell RNA - OE19 [nTPM]":"6.3","Cell RNA - PC-3 [nTPM]":"11.6","Cell RNA - REH [nTPM]":"9.0","Cell RNA - RH-30 [nTPM]":"12.7","Cell RNA - RPMI-8226 [nTPM]":"4.5","Cell RNA - RPTEC TERT1 [nTPM]":"3.4","Cell RNA - RT4 [nTPM]":"5.8","Cell RNA - SCLC-21H [nTPM]":"7.3","Cell RNA - SH-SY5Y [nTPM]":"1.9","Cell RNA - SiHa [nTPM]":"9.4","Cell RNA - SK-BR-3 [nTPM]":"7.6","Cell RNA - SK-MEL-30 [nTPM]":"4.0","Cell RNA - SuSa [nTPM]":"5.1","Cell RNA - T-47d [nTPM]":"8.0","Cell RNA - THP-1 [nTPM]":"6.0","Cell RNA - TIME [nTPM]":"5.6","Cell RNA - U-138 MG [nTPM]":"11.8","Cell RNA - U-2 OS [nTPM]":"11.0","Cell RNA - U-2197 [nTPM]":"10.6","Cell RNA - U-251 MG [nTPM]":"8.1","Cell RNA - U-266\/70 [nTPM]":"4.4","Cell RNA - U-266\/84 [nTPM]":"8.7","Cell RNA - U-698 [nTPM]":"10.3","Cell RNA - U-87 MG [nTPM]":"2.3","Cell RNA - U-937 [nTPM]":"7.9","Cell RNA - WM-115 [nTPM]":"7.0","Blood RNA - basophil [nTPM]":"6.6","Blood RNA - classical monocyte [nTPM]":"0.7","Blood RNA - eosinophil [nTPM]":"2.5","Blood RNA - gdT-cell [nTPM]":"2.0","Blood RNA - intermediate monocyte [nTPM]":"2.0","Blood RNA - MAIT T-cell [nTPM]":"1.1","Blood RNA - memory B-cell [nTPM]":"4.3","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"2.0","Blood RNA - naive CD4 T-cell [nTPM]":"2.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.7","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"1.7","Blood RNA - T-reg [nTPM]":"1.0","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"0.8","Brain RNA - basal ganglia [nTPM]":"1.6","Brain RNA - cerebellum [nTPM]":"1.9","Brain RNA - cerebral cortex [nTPM]":"2.2","Brain RNA - hippocampal formation [nTPM]":"1.0","Brain RNA - hypothalamus [nTPM]":"0.9","Brain RNA - medulla oblongata [nTPM]":"1.0","Brain RNA - midbrain [nTPM]":"0.8","Brain RNA - pons [nTPM]":"1.2","Brain RNA - spinal cord [nTPM]":"0.7","Brain RNA - thalamus [nTPM]":"1.1","Brain RNA - white matter [nTPM]":"1.2","Single Cell Type RNA - Adipocytes [nTPM]":"6.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.1","Single Cell Type RNA - Astrocytes [nTPM]":"9.8","Single Cell Type RNA - B-cells [nTPM]":"8.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"6.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"3.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.6","Single Cell Type RNA - dendritic cells [nTPM]":"5.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.2","Single Cell Type RNA - Early spermatids [nTPM]":"65.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.8","Single Cell Type RNA - Endothelial cells [nTPM]":"5.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"12.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"21.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.5","Single Cell Type RNA - Fibroblasts [nTPM]":"4.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"9.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.7","Single Cell Type RNA - Hepatocytes [nTPM]":"1.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.5","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.6","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"3.8","Single Cell Type RNA - Langerhans cells [nTPM]":"2.9","Single Cell Type RNA - Late spermatids [nTPM]":"206.1","Single Cell Type RNA - Leydig cells [nTPM]":"9.0","Single Cell Type RNA - Macrophages [nTPM]":"4.0","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"5.9","Single Cell Type RNA - Muller glia cells [nTPM]":"4.8","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"22.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.8","Single Cell Type RNA - Peritubular cells [nTPM]":"5.3","Single Cell Type RNA - Plasma cells [nTPM]":"8.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.0","Single Cell Type RNA - Spermatocytes [nTPM]":"26.5","Single Cell Type RNA - Spermatogonia [nTPM]":"14.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.3","Single Cell Type RNA - T-cells [nTPM]":"5.6","Single Cell Type RNA - Theca cells [nTPM]":"9.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"FAR1","Gene synonym":["FLJ22728","MLSTD2","SDR10E1"],"Ensembl":"ENSG00000197601","Gene description":"Fatty acyl-CoA reductase 1","Uniprot":["Q8WVX9"],"Chromosome":"11","Position":"13668668-13732346","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Cataract","Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"437.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017322"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Peroxisomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Peroxisomes"],"Subcellular additional location":null,"Antibody RRID":{"HPA017322":"AB_1848424"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.27e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-3"},"Tissue RNA - adipose tissue [nTPM]":"21.1","Tissue RNA - adrenal gland [nTPM]":"16.2","Tissue RNA - amygdala [nTPM]":"19.3","Tissue RNA - appendix [nTPM]":"23.0","Tissue RNA - basal ganglia [nTPM]":"36.0","Tissue RNA - bone marrow [nTPM]":"74.9","Tissue RNA - breast [nTPM]":"20.6","Tissue RNA - cerebellum [nTPM]":"34.3","Tissue RNA - cerebral cortex [nTPM]":"31.5","Tissue RNA - cervix [nTPM]":"23.8","Tissue RNA - choroid plexus [nTPM]":"24.5","Tissue RNA - colon [nTPM]":"32.9","Tissue RNA - duodenum [nTPM]":"38.7","Tissue RNA - endometrium 1 [nTPM]":"24.7","Tissue RNA - epididymis [nTPM]":"24.9","Tissue RNA - esophagus [nTPM]":"50.9","Tissue RNA - fallopian tube [nTPM]":"17.7","Tissue RNA - gallbladder [nTPM]":"13.7","Tissue RNA - heart muscle [nTPM]":"20.0","Tissue RNA - hippocampal formation [nTPM]":"22.6","Tissue RNA - hypothalamus [nTPM]":"29.7","Tissue RNA - kidney [nTPM]":"14.0","Tissue RNA - liver [nTPM]":"5.0","Tissue RNA - lung [nTPM]":"20.2","Tissue RNA - lymph node [nTPM]":"20.5","Tissue RNA - medulla oblongata [nTPM]":"48.4","Tissue RNA - midbrain [nTPM]":"29.9","Tissue RNA - ovary [nTPM]":"19.9","Tissue RNA - pancreas [nTPM]":"21.3","Tissue RNA - parathyroid gland [nTPM]":"29.1","Tissue RNA - pituitary gland [nTPM]":"15.6","Tissue RNA - placenta [nTPM]":"24.6","Tissue RNA - pons [nTPM]":"44.1","Tissue RNA - prostate [nTPM]":"20.5","Tissue RNA - rectum [nTPM]":"37.6","Tissue RNA - retina [nTPM]":"32.6","Tissue RNA - salivary gland [nTPM]":"18.2","Tissue RNA - seminal vesicle [nTPM]":"15.4","Tissue RNA - skeletal muscle [nTPM]":"15.2","Tissue RNA - skin 1 [nTPM]":"12.2","Tissue RNA - small intestine [nTPM]":"21.1","Tissue RNA - smooth muscle [nTPM]":"30.7","Tissue RNA - spinal cord [nTPM]":"37.3","Tissue RNA - spleen [nTPM]":"20.5","Tissue RNA - stomach 1 [nTPM]":"62.0","Tissue RNA - testis [nTPM]":"20.8","Tissue RNA - thalamus [nTPM]":"32.1","Tissue RNA - thymus [nTPM]":"16.5","Tissue RNA - thyroid gland [nTPM]":"19.8","Tissue RNA - tongue [nTPM]":"18.6","Tissue RNA - tonsil [nTPM]":"23.9","Tissue RNA - urinary bladder [nTPM]":"28.4","Tissue RNA - vagina [nTPM]":"30.0","Tissue RNA - white matter [nTPM]":"94.8","Cell RNA - A-431 [nTPM]":"79.5","Cell RNA - A549 [nTPM]":"50.6","Cell RNA - AF22 [nTPM]":"49.1","Cell RNA - AN3-CA [nTPM]":"38.4","Cell RNA - ASC diff [nTPM]":"45.9","Cell RNA - ASC TERT1 [nTPM]":"52.6","Cell RNA - BEWO [nTPM]":"26.7","Cell RNA - BJ [nTPM]":"69.2","Cell RNA - BJ hTERT+ [nTPM]":"27.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"50.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"52.7","Cell RNA - CACO-2 [nTPM]":"53.5","Cell RNA - CAPAN-2 [nTPM]":"66.4","Cell RNA - Daudi [nTPM]":"100.9","Cell RNA - EFO-21 [nTPM]":"30.2","Cell RNA - fHDF\/TERT166 [nTPM]":"55.5","Cell RNA - GAMG [nTPM]":"74.3","Cell RNA - HaCaT [nTPM]":"84.3","Cell RNA - HAP1 [nTPM]":"73.2","Cell RNA - HBEC3-KT [nTPM]":"69.9","Cell RNA - HBF TERT88 [nTPM]":"76.1","Cell RNA - HDLM-2 [nTPM]":"30.0","Cell RNA - HEK 293 [nTPM]":"59.4","Cell RNA - HEL [nTPM]":"43.4","Cell RNA - HeLa [nTPM]":"44.8","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"44.1","Cell RNA - HL-60 [nTPM]":"87.9","Cell RNA - HMC-1 [nTPM]":"33.7","Cell RNA - HSkMC [nTPM]":"40.2","Cell RNA - hTCEpi [nTPM]":"70.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"36.2","Cell RNA - hTERT-HME1 [nTPM]":"107.7","Cell RNA - hTERT-RPE1 [nTPM]":"36.9","Cell RNA - HUVEC TERT2 [nTPM]":"49.6","Cell RNA - JURKAT [nTPM]":"50.2","Cell RNA - K-562 [nTPM]":"68.9","Cell RNA - Karpas-707 [nTPM]":"29.3","Cell RNA - LHCN-M2 [nTPM]":"41.5","Cell RNA - MCF7 [nTPM]":"39.9","Cell RNA - MOLT-4 [nTPM]":"65.5","Cell RNA - NB-4 [nTPM]":"26.3","Cell RNA - NTERA-2 [nTPM]":"25.8","Cell RNA - OE19 [nTPM]":"100.1","Cell RNA - PC-3 [nTPM]":"72.6","Cell RNA - REH [nTPM]":"56.9","Cell RNA - RH-30 [nTPM]":"62.6","Cell RNA - RPMI-8226 [nTPM]":"28.4","Cell RNA - RPTEC TERT1 [nTPM]":"48.4","Cell RNA - RT4 [nTPM]":"126.4","Cell RNA - SCLC-21H [nTPM]":"37.7","Cell RNA - SH-SY5Y [nTPM]":"27.3","Cell RNA - SiHa [nTPM]":"65.5","Cell RNA - SK-BR-3 [nTPM]":"61.6","Cell RNA - SK-MEL-30 [nTPM]":"34.4","Cell RNA - SuSa [nTPM]":"56.2","Cell RNA - T-47d [nTPM]":"37.8","Cell RNA - THP-1 [nTPM]":"54.1","Cell RNA - TIME [nTPM]":"62.1","Cell RNA - U-138 MG [nTPM]":"68.5","Cell RNA - U-2 OS [nTPM]":"58.2","Cell RNA - U-2197 [nTPM]":"63.7","Cell RNA - U-251 MG [nTPM]":"58.4","Cell RNA - U-266\/70 [nTPM]":"16.4","Cell RNA - U-266\/84 [nTPM]":"59.6","Cell RNA - U-698 [nTPM]":"84.7","Cell RNA - U-87 MG [nTPM]":"43.4","Cell RNA - U-937 [nTPM]":"26.4","Cell RNA - WM-115 [nTPM]":"42.4","Blood RNA - basophil [nTPM]":"10.4","Blood RNA - classical monocyte [nTPM]":"24.9","Blood RNA - eosinophil [nTPM]":"28.0","Blood RNA - gdT-cell [nTPM]":"7.7","Blood RNA - intermediate monocyte [nTPM]":"21.3","Blood RNA - MAIT T-cell [nTPM]":"5.4","Blood RNA - memory B-cell [nTPM]":"3.5","Blood RNA - memory CD4 T-cell [nTPM]":"3.7","Blood RNA - memory CD8 T-cell [nTPM]":"6.6","Blood RNA - myeloid DC [nTPM]":"28.5","Blood RNA - naive B-cell [nTPM]":"5.5","Blood RNA - naive CD4 T-cell [nTPM]":"3.3","Blood RNA - naive CD8 T-cell [nTPM]":"5.5","Blood RNA - neutrophil [nTPM]":"38.9","Blood RNA - NK-cell [nTPM]":"9.1","Blood RNA - non-classical monocyte [nTPM]":"18.2","Blood RNA - plasmacytoid DC [nTPM]":"4.4","Blood RNA - T-reg [nTPM]":"5.3","Blood RNA - total PBMC [nTPM]":"7.7","Brain RNA - amygdala [nTPM]":"19.3","Brain RNA - basal ganglia [nTPM]":"36.0","Brain RNA - cerebellum [nTPM]":"34.3","Brain RNA - cerebral cortex [nTPM]":"31.5","Brain RNA - hippocampal formation [nTPM]":"22.6","Brain RNA - hypothalamus [nTPM]":"29.7","Brain RNA - medulla oblongata [nTPM]":"48.4","Brain RNA - midbrain [nTPM]":"29.9","Brain RNA - pons [nTPM]":"44.1","Brain RNA - spinal cord [nTPM]":"37.3","Brain RNA - thalamus [nTPM]":"32.1","Brain RNA - white matter [nTPM]":"94.8","Single Cell Type RNA - Adipocytes [nTPM]":"38.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.1","Single Cell Type RNA - Astrocytes [nTPM]":"80.0","Single Cell Type RNA - B-cells [nTPM]":"24.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"32.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"41.5","Single Cell Type RNA - Bipolar cells [nTPM]":"46.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"27.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"24.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"26.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.7","Single Cell Type RNA - dendritic cells [nTPM]":"40.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"59.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"12.8","Single Cell Type RNA - Early spermatids [nTPM]":"100.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"21.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"36.5","Single Cell Type RNA - Endothelial cells [nTPM]":"31.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"36.0","Single Cell Type RNA - Erythroid cells [nTPM]":"38.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"146.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.5","Single Cell Type RNA - Fibroblasts [nTPM]":"26.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"114.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.2","Single Cell Type RNA - granulocytes [nTPM]":"38.7","Single Cell Type RNA - Granulosa cells [nTPM]":"23.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"29.6","Single Cell Type RNA - Hepatocytes [nTPM]":"2.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"33.9","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"113.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.8","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"53.5","Single Cell Type RNA - Langerhans cells [nTPM]":"57.0","Single Cell Type RNA - Late spermatids [nTPM]":"181.3","Single Cell Type RNA - Leydig cells [nTPM]":"26.8","Single Cell Type RNA - Macrophages [nTPM]":"48.8","Single Cell Type RNA - Melanocytes [nTPM]":"35.6","Single Cell Type RNA - Microglial cells [nTPM]":"71.2","Single Cell Type RNA - monocytes [nTPM]":"54.8","Single Cell Type RNA - Muller glia cells [nTPM]":"20.6","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"93.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"437.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.3","Single Cell Type RNA - Paneth cells [nTPM]":"43.4","Single Cell Type RNA - Peritubular cells [nTPM]":"25.6","Single Cell Type RNA - Plasma cells [nTPM]":"36.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"50.4","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"29.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"29.3","Single Cell Type RNA - Spermatocytes [nTPM]":"41.6","Single Cell Type RNA - Spermatogonia [nTPM]":"32.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"116.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"19.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.9","Single Cell Type RNA - T-cells [nTPM]":"25.8","Single Cell Type RNA - Theca cells [nTPM]":"17.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"47.7","Single Cell Type RNA - Urothelial cells [nTPM]":"42.0"},{"Gene":"FARS2","Gene synonym":["dJ236A3.1","FARS1","mtPheRS"],"Ensembl":"ENSG00000145982","Gene description":"Phenylalanyl-tRNA synthetase 2, mitochondrial","Uniprot":["O95363"],"Chromosome":"6","Position":"5261044-5829192","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"110.4","Early spermatids":"77.4","Excitatory neurons":"217.0","Inhibitory neurons":"122.6","Late spermatids":"78.8","Microglial cells":"106.8","Oligodendrocyte precursor cells":"186.5","Oligodendrocytes":"122.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018148","HPA028836"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018148":"AB_1848426","HPA028836":"AB_10601377"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.14e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.24e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.4","Tissue RNA - adrenal gland [nTPM]":"12.0","Tissue RNA - amygdala [nTPM]":"8.1","Tissue RNA - appendix [nTPM]":"9.6","Tissue RNA - basal ganglia [nTPM]":"10.9","Tissue RNA - bone marrow [nTPM]":"11.7","Tissue RNA - breast [nTPM]":"11.0","Tissue RNA - cerebellum [nTPM]":"6.1","Tissue RNA - cerebral cortex [nTPM]":"10.8","Tissue RNA - cervix [nTPM]":"8.8","Tissue RNA - choroid plexus [nTPM]":"22.9","Tissue RNA - colon [nTPM]":"10.6","Tissue RNA - duodenum [nTPM]":"7.4","Tissue RNA - endometrium 1 [nTPM]":"9.2","Tissue RNA - epididymis [nTPM]":"7.3","Tissue RNA - esophagus [nTPM]":"9.8","Tissue RNA - fallopian tube [nTPM]":"14.9","Tissue RNA - gallbladder [nTPM]":"6.8","Tissue RNA - heart muscle [nTPM]":"16.0","Tissue RNA - hippocampal formation [nTPM]":"8.4","Tissue RNA - hypothalamus [nTPM]":"9.6","Tissue RNA - kidney [nTPM]":"14.2","Tissue RNA - liver [nTPM]":"14.4","Tissue RNA - lung [nTPM]":"9.6","Tissue RNA - lymph node [nTPM]":"12.4","Tissue RNA - medulla oblongata [nTPM]":"5.8","Tissue RNA - midbrain [nTPM]":"6.7","Tissue RNA - ovary [nTPM]":"7.8","Tissue RNA - pancreas [nTPM]":"10.3","Tissue RNA - parathyroid gland [nTPM]":"13.2","Tissue RNA - pituitary gland [nTPM]":"9.8","Tissue RNA - placenta [nTPM]":"8.9","Tissue RNA - pons [nTPM]":"6.5","Tissue RNA - prostate [nTPM]":"7.3","Tissue RNA - rectum [nTPM]":"11.3","Tissue RNA - retina [nTPM]":"6.8","Tissue RNA - salivary gland [nTPM]":"8.4","Tissue RNA - seminal vesicle [nTPM]":"8.6","Tissue RNA - skeletal muscle [nTPM]":"19.7","Tissue RNA - skin 1 [nTPM]":"11.4","Tissue RNA - small intestine [nTPM]":"7.9","Tissue RNA - smooth muscle [nTPM]":"9.8","Tissue RNA - spinal cord [nTPM]":"6.1","Tissue RNA - spleen [nTPM]":"9.8","Tissue RNA - stomach 1 [nTPM]":"9.9","Tissue RNA - testis [nTPM]":"11.7","Tissue RNA - thalamus [nTPM]":"10.8","Tissue RNA - thymus [nTPM]":"12.5","Tissue RNA - thyroid gland [nTPM]":"14.4","Tissue RNA - tongue [nTPM]":"17.9","Tissue RNA - tonsil [nTPM]":"11.0","Tissue RNA - urinary bladder [nTPM]":"8.8","Tissue RNA - vagina [nTPM]":"8.9","Tissue RNA - white matter [nTPM]":"8.6","Cell RNA - A-431 [nTPM]":"14.2","Cell RNA - A549 [nTPM]":"13.4","Cell RNA - AF22 [nTPM]":"14.1","Cell RNA - AN3-CA [nTPM]":"14.7","Cell RNA - ASC diff [nTPM]":"17.1","Cell RNA - ASC TERT1 [nTPM]":"20.5","Cell RNA - BEWO [nTPM]":"11.6","Cell RNA - BJ [nTPM]":"15.1","Cell RNA - BJ hTERT+ [nTPM]":"17.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.2","Cell RNA - CACO-2 [nTPM]":"18.0","Cell RNA - CAPAN-2 [nTPM]":"10.7","Cell RNA - Daudi [nTPM]":"19.7","Cell RNA - EFO-21 [nTPM]":"23.1","Cell RNA - fHDF\/TERT166 [nTPM]":"14.9","Cell RNA - GAMG [nTPM]":"18.9","Cell RNA - HaCaT [nTPM]":"13.9","Cell RNA - HAP1 [nTPM]":"18.2","Cell RNA - HBEC3-KT [nTPM]":"23.9","Cell RNA - HBF TERT88 [nTPM]":"20.2","Cell RNA - HDLM-2 [nTPM]":"59.5","Cell RNA - HEK 293 [nTPM]":"12.2","Cell RNA - HEL [nTPM]":"7.9","Cell RNA - HeLa [nTPM]":"11.0","Cell RNA - Hep G2 [nTPM]":"16.1","Cell RNA - HHSteC [nTPM]":"8.9","Cell RNA - HL-60 [nTPM]":"18.9","Cell RNA - HMC-1 [nTPM]":"11.4","Cell RNA - HSkMC [nTPM]":"16.5","Cell RNA - hTCEpi [nTPM]":"24.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.9","Cell RNA - hTERT-HME1 [nTPM]":"15.8","Cell RNA - hTERT-RPE1 [nTPM]":"11.4","Cell RNA - HUVEC TERT2 [nTPM]":"23.6","Cell RNA - JURKAT [nTPM]":"21.8","Cell RNA - K-562 [nTPM]":"23.7","Cell RNA - Karpas-707 [nTPM]":"4.5","Cell RNA - LHCN-M2 [nTPM]":"14.6","Cell RNA - MCF7 [nTPM]":"14.5","Cell RNA - MOLT-4 [nTPM]":"20.6","Cell RNA - NB-4 [nTPM]":"21.2","Cell RNA - NTERA-2 [nTPM]":"8.7","Cell RNA - OE19 [nTPM]":"21.7","Cell RNA - PC-3 [nTPM]":"12.9","Cell RNA - REH [nTPM]":"20.0","Cell RNA - RH-30 [nTPM]":"17.6","Cell RNA - RPMI-8226 [nTPM]":"38.9","Cell RNA - RPTEC TERT1 [nTPM]":"18.7","Cell RNA - RT4 [nTPM]":"16.4","Cell RNA - SCLC-21H [nTPM]":"23.9","Cell RNA - SH-SY5Y [nTPM]":"11.8","Cell RNA - SiHa [nTPM]":"14.1","Cell RNA - SK-BR-3 [nTPM]":"11.0","Cell RNA - SK-MEL-30 [nTPM]":"17.6","Cell RNA - SuSa [nTPM]":"18.4","Cell RNA - T-47d [nTPM]":"22.1","Cell RNA - THP-1 [nTPM]":"20.6","Cell RNA - TIME [nTPM]":"13.7","Cell RNA - U-138 MG [nTPM]":"20.7","Cell RNA - U-2 OS [nTPM]":"9.4","Cell RNA - U-2197 [nTPM]":"12.3","Cell RNA - U-251 MG [nTPM]":"19.8","Cell RNA - U-266\/70 [nTPM]":"9.3","Cell RNA - U-266\/84 [nTPM]":"34.2","Cell RNA - U-698 [nTPM]":"10.9","Cell RNA - U-87 MG [nTPM]":"11.6","Cell RNA - U-937 [nTPM]":"11.1","Cell RNA - WM-115 [nTPM]":"26.6","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"14.7","Blood RNA - eosinophil [nTPM]":"5.2","Blood RNA - gdT-cell [nTPM]":"23.1","Blood RNA - intermediate monocyte [nTPM]":"16.7","Blood RNA - MAIT T-cell [nTPM]":"20.3","Blood RNA - memory B-cell [nTPM]":"20.0","Blood RNA - memory CD4 T-cell [nTPM]":"20.5","Blood RNA - memory CD8 T-cell [nTPM]":"21.2","Blood RNA - myeloid DC [nTPM]":"26.0","Blood RNA - naive B-cell [nTPM]":"17.5","Blood RNA - naive CD4 T-cell [nTPM]":"22.3","Blood RNA - naive CD8 T-cell [nTPM]":"22.1","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"24.6","Blood RNA - non-classical monocyte [nTPM]":"11.9","Blood RNA - plasmacytoid DC [nTPM]":"15.5","Blood RNA - T-reg [nTPM]":"28.0","Blood RNA - total PBMC [nTPM]":"17.6","Brain RNA - amygdala [nTPM]":"8.1","Brain RNA - basal ganglia [nTPM]":"10.9","Brain RNA - cerebellum [nTPM]":"6.1","Brain RNA - cerebral cortex [nTPM]":"10.8","Brain RNA - hippocampal formation [nTPM]":"8.4","Brain RNA - hypothalamus [nTPM]":"9.6","Brain RNA - medulla oblongata [nTPM]":"5.8","Brain RNA - midbrain [nTPM]":"6.7","Brain RNA - pons [nTPM]":"6.5","Brain RNA - spinal cord [nTPM]":"6.1","Brain RNA - thalamus [nTPM]":"10.8","Brain RNA - white matter [nTPM]":"8.6","Single Cell Type RNA - Adipocytes [nTPM]":"10.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.7","Single Cell Type RNA - Astrocytes [nTPM]":"110.4","Single Cell Type RNA - B-cells [nTPM]":"15.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"8.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"8.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.5","Single Cell Type RNA - dendritic cells [nTPM]":"10.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"27.4","Single Cell Type RNA - Ductal cells [nTPM]":"14.6","Single Cell Type RNA - Early spermatids [nTPM]":"77.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.6","Single Cell Type RNA - Endothelial cells [nTPM]":"10.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.7","Single Cell Type RNA - Erythroid cells [nTPM]":"13.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"217.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.9","Single Cell Type RNA - Fibroblasts [nTPM]":"10.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.2","Single Cell Type RNA - granulocytes [nTPM]":"22.2","Single Cell Type RNA - Granulosa cells [nTPM]":"14.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.4","Single Cell Type RNA - Hepatocytes [nTPM]":"12.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"122.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.4","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"12.5","Single Cell Type RNA - Langerhans cells [nTPM]":"11.6","Single Cell Type RNA - Late spermatids [nTPM]":"78.8","Single Cell Type RNA - Leydig cells [nTPM]":"6.2","Single Cell Type RNA - Macrophages [nTPM]":"17.4","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"106.8","Single Cell Type RNA - monocytes [nTPM]":"9.4","Single Cell Type RNA - Muller glia cells [nTPM]":"14.2","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"186.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"122.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.8","Single Cell Type RNA - Paneth cells [nTPM]":"8.6","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"16.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"30.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.8","Single Cell Type RNA - Spermatocytes [nTPM]":"19.2","Single Cell Type RNA - Spermatogonia [nTPM]":"9.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.7","Single Cell Type RNA - T-cells [nTPM]":"16.2","Single Cell Type RNA - Theca cells [nTPM]":"24.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.9","Single Cell Type RNA - Urothelial cells [nTPM]":"13.2"},{"Gene":"FARSB","Gene synonym":["FARSLB","FRSB","PheHB"],"Ensembl":"ENSG00000116120","Gene description":"Phenylalanyl-tRNA synthetase subunit beta","Uniprot":["Q9NSD9"],"Chromosome":"2","Position":"222566899-222656092","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Disease variant","Mental retardation","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036677","HPA036678","HPA061398"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"28000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA036677":"AB_2675242","HPA036678":"AB_10673504","HPA061398":"AB_2684504"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.95e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.42e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.45e-10"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.89e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.21e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.25e-4"},"Tissue RNA - adipose tissue [nTPM]":"12.8","Tissue RNA - adrenal gland [nTPM]":"10.9","Tissue RNA - amygdala [nTPM]":"9.5","Tissue RNA - appendix [nTPM]":"7.6","Tissue RNA - basal ganglia [nTPM]":"10.0","Tissue RNA - bone marrow [nTPM]":"8.0","Tissue RNA - breast [nTPM]":"12.8","Tissue RNA - cerebellum [nTPM]":"10.4","Tissue RNA - cerebral cortex [nTPM]":"11.3","Tissue RNA - cervix [nTPM]":"13.1","Tissue RNA - choroid plexus [nTPM]":"6.5","Tissue RNA - colon [nTPM]":"14.7","Tissue RNA - duodenum [nTPM]":"9.1","Tissue RNA - endometrium 1 [nTPM]":"13.5","Tissue RNA - epididymis [nTPM]":"6.5","Tissue RNA - esophagus [nTPM]":"20.7","Tissue RNA - fallopian tube [nTPM]":"11.9","Tissue RNA - gallbladder [nTPM]":"3.9","Tissue RNA - heart muscle [nTPM]":"16.7","Tissue RNA - hippocampal formation [nTPM]":"10.2","Tissue RNA - hypothalamus [nTPM]":"10.7","Tissue RNA - kidney [nTPM]":"11.8","Tissue RNA - liver [nTPM]":"14.1","Tissue RNA - lung [nTPM]":"9.4","Tissue RNA - lymph node [nTPM]":"7.4","Tissue RNA - medulla oblongata [nTPM]":"9.6","Tissue RNA - midbrain [nTPM]":"9.4","Tissue RNA - ovary [nTPM]":"14.3","Tissue RNA - pancreas [nTPM]":"15.6","Tissue RNA - parathyroid gland [nTPM]":"8.0","Tissue RNA - pituitary gland [nTPM]":"13.2","Tissue RNA - placenta [nTPM]":"5.0","Tissue RNA - pons [nTPM]":"10.8","Tissue RNA - prostate [nTPM]":"11.2","Tissue RNA - rectum [nTPM]":"11.1","Tissue RNA - retina [nTPM]":"10.0","Tissue RNA - salivary gland [nTPM]":"10.4","Tissue RNA - seminal vesicle [nTPM]":"6.1","Tissue RNA - skeletal muscle [nTPM]":"31.9","Tissue RNA - skin 1 [nTPM]":"14.9","Tissue RNA - small intestine [nTPM]":"10.8","Tissue RNA - smooth muscle [nTPM]":"8.1","Tissue RNA - spinal cord [nTPM]":"8.4","Tissue RNA - spleen [nTPM]":"9.7","Tissue RNA - stomach 1 [nTPM]":"13.9","Tissue RNA - testis [nTPM]":"13.5","Tissue RNA - thalamus [nTPM]":"9.9","Tissue RNA - thymus [nTPM]":"7.7","Tissue RNA - thyroid gland [nTPM]":"9.7","Tissue RNA - tongue [nTPM]":"13.2","Tissue RNA - tonsil [nTPM]":"8.3","Tissue RNA - urinary bladder [nTPM]":"13.1","Tissue RNA - vagina [nTPM]":"13.7","Tissue RNA - white matter [nTPM]":"9.4","Cell RNA - A-431 [nTPM]":"31.1","Cell RNA - A549 [nTPM]":"17.8","Cell RNA - AF22 [nTPM]":"20.7","Cell RNA - AN3-CA [nTPM]":"27.2","Cell RNA - ASC diff [nTPM]":"18.0","Cell RNA - ASC TERT1 [nTPM]":"26.3","Cell RNA - BEWO [nTPM]":"31.0","Cell RNA - BJ [nTPM]":"31.0","Cell RNA - BJ hTERT+ [nTPM]":"19.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"29.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.9","Cell RNA - CACO-2 [nTPM]":"45.3","Cell RNA - CAPAN-2 [nTPM]":"16.6","Cell RNA - Daudi [nTPM]":"15.3","Cell RNA - EFO-21 [nTPM]":"22.7","Cell RNA - fHDF\/TERT166 [nTPM]":"22.6","Cell RNA - GAMG [nTPM]":"24.7","Cell RNA - HaCaT [nTPM]":"25.8","Cell RNA - HAP1 [nTPM]":"39.7","Cell RNA - HBEC3-KT [nTPM]":"34.7","Cell RNA - HBF TERT88 [nTPM]":"43.0","Cell RNA - HDLM-2 [nTPM]":"22.8","Cell RNA - HEK 293 [nTPM]":"20.7","Cell RNA - HEL [nTPM]":"35.1","Cell RNA - HeLa [nTPM]":"18.9","Cell RNA - Hep G2 [nTPM]":"28.8","Cell RNA - HHSteC [nTPM]":"27.9","Cell RNA - HL-60 [nTPM]":"51.9","Cell RNA - HMC-1 [nTPM]":"14.0","Cell RNA - HSkMC [nTPM]":"17.6","Cell RNA - hTCEpi [nTPM]":"27.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"33.9","Cell RNA - hTERT-HME1 [nTPM]":"51.2","Cell RNA - hTERT-RPE1 [nTPM]":"10.5","Cell RNA - HUVEC TERT2 [nTPM]":"28.3","Cell RNA - JURKAT [nTPM]":"26.4","Cell RNA - K-562 [nTPM]":"53.5","Cell RNA - Karpas-707 [nTPM]":"30.3","Cell RNA - LHCN-M2 [nTPM]":"36.1","Cell RNA - MCF7 [nTPM]":"28.9","Cell RNA - MOLT-4 [nTPM]":"31.2","Cell RNA - NB-4 [nTPM]":"29.2","Cell RNA - NTERA-2 [nTPM]":"26.6","Cell RNA - OE19 [nTPM]":"37.0","Cell RNA - PC-3 [nTPM]":"22.0","Cell RNA - REH [nTPM]":"30.2","Cell RNA - RH-30 [nTPM]":"49.4","Cell RNA - RPMI-8226 [nTPM]":"49.8","Cell RNA - RPTEC TERT1 [nTPM]":"24.5","Cell RNA - RT4 [nTPM]":"19.9","Cell RNA - SCLC-21H [nTPM]":"33.4","Cell RNA - SH-SY5Y [nTPM]":"11.2","Cell RNA - SiHa [nTPM]":"12.9","Cell RNA - SK-BR-3 [nTPM]":"22.4","Cell RNA - SK-MEL-30 [nTPM]":"27.6","Cell RNA - SuSa [nTPM]":"24.7","Cell RNA - T-47d [nTPM]":"20.9","Cell RNA - THP-1 [nTPM]":"21.3","Cell RNA - TIME [nTPM]":"15.8","Cell RNA - U-138 MG [nTPM]":"25.5","Cell RNA - U-2 OS [nTPM]":"21.1","Cell RNA - U-2197 [nTPM]":"37.8","Cell RNA - U-251 MG [nTPM]":"38.5","Cell RNA - U-266\/70 [nTPM]":"14.8","Cell RNA - U-266\/84 [nTPM]":"15.5","Cell RNA - U-698 [nTPM]":"54.5","Cell RNA - U-87 MG [nTPM]":"20.8","Cell RNA - U-937 [nTPM]":"34.0","Cell RNA - WM-115 [nTPM]":"27.2","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"7.6","Blood RNA - eosinophil [nTPM]":"1.2","Blood RNA - gdT-cell [nTPM]":"9.6","Blood RNA - intermediate monocyte [nTPM]":"9.4","Blood RNA - MAIT T-cell [nTPM]":"14.3","Blood RNA - memory B-cell [nTPM]":"15.1","Blood RNA - memory CD4 T-cell [nTPM]":"12.8","Blood RNA - memory CD8 T-cell [nTPM]":"11.9","Blood RNA - myeloid DC [nTPM]":"14.4","Blood RNA - naive B-cell [nTPM]":"12.7","Blood RNA - naive CD4 T-cell [nTPM]":"16.4","Blood RNA - naive CD8 T-cell [nTPM]":"14.2","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"17.4","Blood RNA - non-classical monocyte [nTPM]":"11.3","Blood RNA - plasmacytoid DC [nTPM]":"7.2","Blood RNA - T-reg [nTPM]":"12.5","Blood RNA - total PBMC [nTPM]":"13.7","Brain RNA - amygdala [nTPM]":"9.5","Brain RNA - basal ganglia [nTPM]":"10.0","Brain RNA - cerebellum [nTPM]":"10.4","Brain RNA - cerebral cortex [nTPM]":"11.3","Brain RNA - hippocampal formation [nTPM]":"10.2","Brain RNA - hypothalamus [nTPM]":"10.7","Brain RNA - medulla oblongata [nTPM]":"9.6","Brain RNA - midbrain [nTPM]":"9.4","Brain RNA - pons [nTPM]":"10.8","Brain RNA - spinal cord [nTPM]":"8.4","Brain RNA - thalamus [nTPM]":"9.9","Brain RNA - white matter [nTPM]":"9.4","Single Cell Type RNA - Adipocytes [nTPM]":"10.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.4","Single Cell Type RNA - Astrocytes [nTPM]":"21.2","Single Cell Type RNA - B-cells [nTPM]":"25.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"19.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"32.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.4","Single Cell Type RNA - Bipolar cells [nTPM]":"17.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"28.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"18.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"37.0","Single Cell Type RNA - dendritic cells [nTPM]":"7.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"24.7","Single Cell Type RNA - Early spermatids [nTPM]":"57.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.8","Single Cell Type RNA - Endothelial cells [nTPM]":"13.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.9","Single Cell Type RNA - Erythroid cells [nTPM]":"24.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"50.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"43.3","Single Cell Type RNA - Fibroblasts [nTPM]":"18.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.6","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"21.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"17.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"27.4","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"56.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.9","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"10.1","Single Cell Type RNA - Langerhans cells [nTPM]":"9.7","Single Cell Type RNA - Late spermatids [nTPM]":"73.1","Single Cell Type RNA - Leydig cells [nTPM]":"15.2","Single Cell Type RNA - Macrophages [nTPM]":"11.8","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"26.2","Single Cell Type RNA - monocytes [nTPM]":"11.3","Single Cell Type RNA - Muller glia cells [nTPM]":"13.2","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"38.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"38.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.8","Single Cell Type RNA - Paneth cells [nTPM]":"11.3","Single Cell Type RNA - Peritubular cells [nTPM]":"19.9","Single Cell Type RNA - Plasma cells [nTPM]":"27.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"31.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"34.4","Single Cell Type RNA - Spermatocytes [nTPM]":"67.4","Single Cell Type RNA - Spermatogonia [nTPM]":"33.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.2","Single Cell Type RNA - T-cells [nTPM]":"16.9","Single Cell Type RNA - Theca cells [nTPM]":"24.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"45.8","Single Cell Type RNA - Urothelial cells [nTPM]":"14.3"},{"Gene":"FBH1","Gene synonym":["Fbx18","FBXO18","FLJ14590"],"Ensembl":"ENSG00000134452","Gene description":"F-box DNA helicase 1","Uniprot":["Q8NFZ0"],"Chromosome":"10","Position":"5890203-5937594","Protein class":["Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["DNA damage","DNA repair","Ubl conjugation pathway"],"Molecular function":["DNA-binding","Helicase","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"22.4","Distal tubular cells":"21.5","Granulosa cells":"23.6","Syncytiotrophoblasts":"32.0","Theca cells":"27.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002844"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA002844":"AB_1078829"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.73e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.54e-2"},"Tissue RNA - adipose tissue [nTPM]":"28.7","Tissue RNA - adrenal gland [nTPM]":"38.8","Tissue RNA - amygdala [nTPM]":"17.5","Tissue RNA - appendix [nTPM]":"22.8","Tissue RNA - basal ganglia [nTPM]":"20.3","Tissue RNA - bone marrow [nTPM]":"24.6","Tissue RNA - breast [nTPM]":"26.8","Tissue RNA - cerebellum [nTPM]":"17.7","Tissue RNA - cerebral cortex [nTPM]":"19.1","Tissue RNA - cervix [nTPM]":"32.4","Tissue RNA - choroid plexus [nTPM]":"25.7","Tissue RNA - colon [nTPM]":"30.4","Tissue RNA - duodenum [nTPM]":"24.6","Tissue RNA - endometrium 1 [nTPM]":"34.3","Tissue RNA - epididymis [nTPM]":"21.3","Tissue RNA - esophagus [nTPM]":"24.0","Tissue RNA - fallopian tube [nTPM]":"36.4","Tissue RNA - gallbladder [nTPM]":"23.0","Tissue RNA - heart muscle [nTPM]":"44.5","Tissue RNA - hippocampal formation [nTPM]":"17.2","Tissue RNA - hypothalamus [nTPM]":"18.0","Tissue RNA - kidney [nTPM]":"25.2","Tissue RNA - liver [nTPM]":"28.8","Tissue RNA - lung [nTPM]":"27.6","Tissue RNA - lymph node [nTPM]":"27.6","Tissue RNA - medulla oblongata [nTPM]":"17.7","Tissue RNA - midbrain [nTPM]":"18.2","Tissue RNA - ovary [nTPM]":"30.7","Tissue RNA - pancreas [nTPM]":"21.9","Tissue RNA - parathyroid gland [nTPM]":"28.5","Tissue RNA - pituitary gland [nTPM]":"26.1","Tissue RNA - placenta [nTPM]":"26.6","Tissue RNA - pons [nTPM]":"18.0","Tissue RNA - prostate [nTPM]":"28.6","Tissue RNA - rectum [nTPM]":"24.2","Tissue RNA - retina [nTPM]":"14.8","Tissue RNA - salivary gland [nTPM]":"24.3","Tissue RNA - seminal vesicle [nTPM]":"25.8","Tissue RNA - skeletal muscle [nTPM]":"30.3","Tissue RNA - skin 1 [nTPM]":"30.4","Tissue RNA - small intestine [nTPM]":"29.7","Tissue RNA - smooth muscle [nTPM]":"30.1","Tissue RNA - spinal cord [nTPM]":"17.8","Tissue RNA - spleen [nTPM]":"35.3","Tissue RNA - stomach 1 [nTPM]":"27.6","Tissue RNA - testis [nTPM]":"24.7","Tissue RNA - thalamus [nTPM]":"19.2","Tissue RNA - thymus [nTPM]":"40.2","Tissue RNA - thyroid gland [nTPM]":"25.2","Tissue RNA - tongue [nTPM]":"27.4","Tissue RNA - tonsil [nTPM]":"27.2","Tissue RNA - urinary bladder [nTPM]":"28.8","Tissue RNA - vagina [nTPM]":"27.1","Tissue RNA - white matter [nTPM]":"19.0","Cell RNA - A-431 [nTPM]":"31.8","Cell RNA - A549 [nTPM]":"34.0","Cell RNA - AF22 [nTPM]":"31.3","Cell RNA - AN3-CA [nTPM]":"34.4","Cell RNA - ASC diff [nTPM]":"70.4","Cell RNA - ASC TERT1 [nTPM]":"46.3","Cell RNA - BEWO [nTPM]":"28.1","Cell RNA - BJ [nTPM]":"35.9","Cell RNA - BJ hTERT+ [nTPM]":"24.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"34.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"38.8","Cell RNA - CACO-2 [nTPM]":"40.4","Cell RNA - CAPAN-2 [nTPM]":"28.3","Cell RNA - Daudi [nTPM]":"29.6","Cell RNA - EFO-21 [nTPM]":"23.0","Cell RNA - fHDF\/TERT166 [nTPM]":"52.5","Cell RNA - GAMG [nTPM]":"16.7","Cell RNA - HaCaT [nTPM]":"46.3","Cell RNA - HAP1 [nTPM]":"42.6","Cell RNA - HBEC3-KT [nTPM]":"38.2","Cell RNA - HBF TERT88 [nTPM]":"31.3","Cell RNA - HDLM-2 [nTPM]":"32.2","Cell RNA - HEK 293 [nTPM]":"31.5","Cell RNA - HEL [nTPM]":"28.6","Cell RNA - HeLa [nTPM]":"27.3","Cell RNA - Hep G2 [nTPM]":"34.8","Cell RNA - HHSteC [nTPM]":"48.2","Cell RNA - HL-60 [nTPM]":"14.2","Cell RNA - HMC-1 [nTPM]":"26.4","Cell RNA - HSkMC [nTPM]":"58.2","Cell RNA - hTCEpi [nTPM]":"36.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"44.2","Cell RNA - hTERT-HME1 [nTPM]":"19.4","Cell RNA - hTERT-RPE1 [nTPM]":"44.0","Cell RNA - HUVEC TERT2 [nTPM]":"59.7","Cell RNA - JURKAT [nTPM]":"39.7","Cell RNA - K-562 [nTPM]":"50.9","Cell RNA - Karpas-707 [nTPM]":"30.4","Cell RNA - LHCN-M2 [nTPM]":"37.3","Cell RNA - MCF7 [nTPM]":"48.1","Cell RNA - MOLT-4 [nTPM]":"34.5","Cell RNA - NB-4 [nTPM]":"20.9","Cell RNA - NTERA-2 [nTPM]":"14.3","Cell RNA - OE19 [nTPM]":"54.7","Cell RNA - PC-3 [nTPM]":"18.9","Cell RNA - REH [nTPM]":"37.6","Cell RNA - RH-30 [nTPM]":"14.8","Cell RNA - RPMI-8226 [nTPM]":"49.9","Cell RNA - RPTEC TERT1 [nTPM]":"34.0","Cell RNA - RT4 [nTPM]":"25.5","Cell RNA - SCLC-21H [nTPM]":"17.7","Cell RNA - SH-SY5Y [nTPM]":"26.6","Cell RNA - SiHa [nTPM]":"36.8","Cell RNA - SK-BR-3 [nTPM]":"33.1","Cell RNA - SK-MEL-30 [nTPM]":"50.8","Cell RNA - SuSa [nTPM]":"35.7","Cell RNA - T-47d [nTPM]":"33.7","Cell RNA - THP-1 [nTPM]":"28.5","Cell RNA - TIME [nTPM]":"37.9","Cell RNA - U-138 MG [nTPM]":"22.1","Cell RNA - U-2 OS [nTPM]":"24.7","Cell RNA - U-2197 [nTPM]":"59.1","Cell RNA - U-251 MG [nTPM]":"28.1","Cell RNA - U-266\/70 [nTPM]":"30.9","Cell RNA - U-266\/84 [nTPM]":"26.1","Cell RNA - U-698 [nTPM]":"16.3","Cell RNA - U-87 MG [nTPM]":"29.8","Cell RNA - U-937 [nTPM]":"20.7","Cell RNA - WM-115 [nTPM]":"15.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.1","Blood RNA - eosinophil [nTPM]":"3.3","Blood RNA - gdT-cell [nTPM]":"1.9","Blood RNA - intermediate monocyte [nTPM]":"1.7","Blood RNA - MAIT T-cell [nTPM]":"1.3","Blood RNA - memory B-cell [nTPM]":"3.0","Blood RNA - memory CD4 T-cell [nTPM]":"2.0","Blood RNA - memory CD8 T-cell [nTPM]":"2.5","Blood RNA - myeloid DC [nTPM]":"2.0","Blood RNA - naive B-cell [nTPM]":"4.1","Blood RNA - naive CD4 T-cell [nTPM]":"2.5","Blood RNA - naive CD8 T-cell [nTPM]":"1.8","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"4.6","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"4.0","Blood RNA - T-reg [nTPM]":"6.2","Blood RNA - total PBMC [nTPM]":"1.7","Brain RNA - amygdala [nTPM]":"17.5","Brain RNA - basal ganglia [nTPM]":"20.3","Brain RNA - cerebellum [nTPM]":"17.7","Brain RNA - cerebral cortex [nTPM]":"19.1","Brain RNA - hippocampal formation [nTPM]":"17.2","Brain RNA - hypothalamus [nTPM]":"18.0","Brain RNA - medulla oblongata [nTPM]":"17.7","Brain RNA - midbrain [nTPM]":"18.2","Brain RNA - pons [nTPM]":"18.0","Brain RNA - spinal cord [nTPM]":"17.8","Brain RNA - thalamus [nTPM]":"19.2","Brain RNA - white matter [nTPM]":"19.0","Single Cell Type RNA - Adipocytes [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"3.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.3","Single Cell Type RNA - dendritic cells [nTPM]":"9.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"16.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.0","Single Cell Type RNA - Endothelial cells [nTPM]":"7.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.4","Single Cell Type RNA - Fibroblasts [nTPM]":"9.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"23.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"5.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"10.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"3.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"20.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"32.0","Single Cell Type RNA - T-cells [nTPM]":"4.4","Single Cell Type RNA - Theca cells [nTPM]":"27.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"FBP1","Gene synonym":["FBP"],"Ensembl":"ENSG00000165140","Gene description":"Fructose-bisphosphatase 1","Uniprot":["P09467"],"Chromosome":"9","Position":"94603133-94640249","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism","Gluconeogenesis"],"Molecular function":["Allosteric enzyme","Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"324.4","kidney":"297.8","liver":"893.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"500.4","Macrophages":"238.6","Proximal enterocytes":"1095.0","Proximal tubular cells":"864.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"404.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"75.2","MCF7":"243.4","OE19":"54.5","RT4":"157.0","U-698":"170.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005857","HPA012513","CAB033869"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"21000000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB033869":"AB_1121520","HPA005857":"AB_1848445","HPA012513":"AB_1848446"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.16e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.79e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.86e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.64e-5"},"Tissue RNA - adipose tissue [nTPM]":"13.7","Tissue RNA - adrenal gland [nTPM]":"27.4","Tissue RNA - amygdala [nTPM]":"1.6","Tissue RNA - appendix [nTPM]":"12.7","Tissue RNA - basal ganglia [nTPM]":"1.8","Tissue RNA - bone marrow [nTPM]":"15.0","Tissue RNA - breast [nTPM]":"41.4","Tissue RNA - cerebellum [nTPM]":"1.8","Tissue RNA - cerebral cortex [nTPM]":"5.7","Tissue RNA - cervix [nTPM]":"19.9","Tissue RNA - choroid plexus [nTPM]":"2.6","Tissue RNA - colon [nTPM]":"29.8","Tissue RNA - duodenum [nTPM]":"324.4","Tissue RNA - endometrium 1 [nTPM]":"3.6","Tissue RNA - epididymis [nTPM]":"15.8","Tissue RNA - esophagus [nTPM]":"2.7","Tissue RNA - fallopian tube [nTPM]":"7.1","Tissue RNA - gallbladder [nTPM]":"34.4","Tissue RNA - heart muscle [nTPM]":"2.9","Tissue RNA - hippocampal formation [nTPM]":"1.5","Tissue RNA - hypothalamus [nTPM]":"2.2","Tissue RNA - kidney [nTPM]":"297.8","Tissue RNA - liver [nTPM]":"893.2","Tissue RNA - lung [nTPM]":"165.9","Tissue RNA - lymph node [nTPM]":"6.8","Tissue RNA - medulla oblongata [nTPM]":"3.6","Tissue RNA - midbrain [nTPM]":"2.6","Tissue RNA - ovary [nTPM]":"1.1","Tissue RNA - pancreas [nTPM]":"41.4","Tissue RNA - parathyroid gland [nTPM]":"107.9","Tissue RNA - pituitary gland [nTPM]":"8.6","Tissue RNA - placenta [nTPM]":"3.0","Tissue RNA - pons [nTPM]":"2.9","Tissue RNA - prostate [nTPM]":"25.8","Tissue RNA - rectum [nTPM]":"30.5","Tissue RNA - retina [nTPM]":"0.7","Tissue RNA - salivary gland [nTPM]":"53.2","Tissue RNA - seminal vesicle [nTPM]":"28.9","Tissue RNA - skeletal muscle [nTPM]":"1.3","Tissue RNA - skin 1 [nTPM]":"8.1","Tissue RNA - small intestine [nTPM]":"258.1","Tissue RNA - smooth muscle [nTPM]":"8.8","Tissue RNA - spinal cord [nTPM]":"2.6","Tissue RNA - spleen [nTPM]":"12.2","Tissue RNA - stomach 1 [nTPM]":"85.6","Tissue RNA - testis [nTPM]":"2.5","Tissue RNA - thalamus [nTPM]":"3.2","Tissue RNA - thymus [nTPM]":"2.2","Tissue RNA - thyroid gland [nTPM]":"16.8","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"7.8","Tissue RNA - urinary bladder [nTPM]":"70.8","Tissue RNA - vagina [nTPM]":"6.7","Tissue RNA - white matter [nTPM]":"3.8","Cell RNA - A-431 [nTPM]":"0.5","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.7","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.6","Cell RNA - CAPAN-2 [nTPM]":"3.8","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.8","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"75.2","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"2.9","Cell RNA - Hep G2 [nTPM]":"1.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"1.5","Cell RNA - HMC-1 [nTPM]":"18.8","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"2.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"243.4","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"4.4","Cell RNA - NTERA-2 [nTPM]":"1.1","Cell RNA - OE19 [nTPM]":"54.5","Cell RNA - PC-3 [nTPM]":"9.5","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.9","Cell RNA - RPMI-8226 [nTPM]":"1.9","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"157.0","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"5.6","Cell RNA - SiHa [nTPM]":"0.6","Cell RNA - SK-BR-3 [nTPM]":"44.5","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.9","Cell RNA - T-47d [nTPM]":"26.7","Cell RNA - THP-1 [nTPM]":"7.7","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"1.0","Cell RNA - U-2197 [nTPM]":"0.8","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"1.1","Cell RNA - U-698 [nTPM]":"170.4","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"1.4","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"63.3","Blood RNA - classical monocyte [nTPM]":"68.4","Blood RNA - eosinophil [nTPM]":"404.3","Blood RNA - gdT-cell [nTPM]":"7.9","Blood RNA - intermediate monocyte [nTPM]":"162.3","Blood RNA - MAIT T-cell [nTPM]":"11.7","Blood RNA - memory B-cell [nTPM]":"3.0","Blood RNA - memory CD4 T-cell [nTPM]":"4.6","Blood RNA - memory CD8 T-cell [nTPM]":"4.6","Blood RNA - myeloid DC [nTPM]":"90.1","Blood RNA - naive B-cell [nTPM]":"3.2","Blood RNA - naive CD4 T-cell [nTPM]":"16.2","Blood RNA - naive CD8 T-cell [nTPM]":"8.3","Blood RNA - neutrophil [nTPM]":"12.1","Blood RNA - NK-cell [nTPM]":"15.4","Blood RNA - non-classical monocyte [nTPM]":"90.7","Blood RNA - plasmacytoid DC [nTPM]":"32.1","Blood RNA - T-reg [nTPM]":"2.3","Blood RNA - total PBMC [nTPM]":"33.1","Brain RNA - amygdala [nTPM]":"1.6","Brain RNA - basal ganglia [nTPM]":"1.8","Brain RNA - cerebellum [nTPM]":"1.8","Brain RNA - cerebral cortex [nTPM]":"5.7","Brain RNA - hippocampal formation [nTPM]":"1.5","Brain RNA - hypothalamus [nTPM]":"2.2","Brain RNA - medulla oblongata [nTPM]":"3.6","Brain RNA - midbrain [nTPM]":"2.6","Brain RNA - pons [nTPM]":"2.9","Brain RNA - spinal cord [nTPM]":"2.6","Brain RNA - thalamus [nTPM]":"3.2","Brain RNA - white matter [nTPM]":"3.8","Single Cell Type RNA - Adipocytes [nTPM]":"2.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"76.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"182.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"10.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"62.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"102.9","Single Cell Type RNA - Club cells [nTPM]":"41.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"62.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.1","Single Cell Type RNA - dendritic cells [nTPM]":"14.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"26.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"111.6","Single Cell Type RNA - Ductal cells [nTPM]":"21.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"4.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"31.9","Single Cell Type RNA - Erythroid cells [nTPM]":"24.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"62.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.7","Single Cell Type RNA - Fibroblasts [nTPM]":"5.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"102.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.2","Single Cell Type RNA - granulocytes [nTPM]":"47.4","Single Cell Type RNA - Granulosa cells [nTPM]":"16.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.1","Single Cell Type RNA - Hepatocytes [nTPM]":"500.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"177.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"61.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"79.9","Single Cell Type RNA - Langerhans cells [nTPM]":"32.1","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"238.6","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"20.1","Single Cell Type RNA - Muller glia cells [nTPM]":"2.6","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"24.0","Single Cell Type RNA - Paneth cells [nTPM]":"77.6","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"18.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1095.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"864.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.1","Single Cell Type RNA - T-cells [nTPM]":"12.1","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"90.4","Single Cell Type RNA - Urothelial cells [nTPM]":"68.1"},{"Gene":"FCSK","Gene synonym":["FLJ39408","FUK"],"Ensembl":"ENSG00000157353","Gene description":"Fucose kinase","Uniprot":["Q8N0W3"],"Chromosome":"16","Position":"70454595-70480274","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"2.7","Cardiomyocytes":"4.2","Cytotrophoblasts":"5.5","Extravillous trophoblasts":"3.0","Hofbauer cells":"5.0","Syncytiotrophoblasts":"5.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041971"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA041971":"AB_10795648"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.79e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.91e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.38e-4"},"Tissue RNA - adipose tissue [nTPM]":"3.9","Tissue RNA - adrenal gland [nTPM]":"7.2","Tissue RNA - amygdala [nTPM]":"5.4","Tissue RNA - appendix [nTPM]":"5.4","Tissue RNA - basal ganglia [nTPM]":"7.1","Tissue RNA - bone marrow [nTPM]":"5.0","Tissue RNA - breast [nTPM]":"4.9","Tissue RNA - cerebellum [nTPM]":"8.2","Tissue RNA - cerebral cortex [nTPM]":"7.7","Tissue RNA - cervix [nTPM]":"5.6","Tissue RNA - choroid plexus [nTPM]":"7.5","Tissue RNA - colon [nTPM]":"7.5","Tissue RNA - duodenum [nTPM]":"10.1","Tissue RNA - endometrium 1 [nTPM]":"4.9","Tissue RNA - epididymis [nTPM]":"2.4","Tissue RNA - esophagus [nTPM]":"5.6","Tissue RNA - fallopian tube [nTPM]":"5.5","Tissue RNA - gallbladder [nTPM]":"3.8","Tissue RNA - heart muscle [nTPM]":"4.3","Tissue RNA - hippocampal formation [nTPM]":"5.3","Tissue RNA - hypothalamus [nTPM]":"5.0","Tissue RNA - kidney [nTPM]":"8.9","Tissue RNA - liver [nTPM]":"8.2","Tissue RNA - lung [nTPM]":"4.8","Tissue RNA - lymph node [nTPM]":"5.4","Tissue RNA - medulla oblongata [nTPM]":"6.4","Tissue RNA - midbrain [nTPM]":"4.6","Tissue RNA - ovary [nTPM]":"6.6","Tissue RNA - pancreas [nTPM]":"8.3","Tissue RNA - parathyroid gland [nTPM]":"9.1","Tissue RNA - pituitary gland [nTPM]":"9.8","Tissue RNA - placenta [nTPM]":"3.6","Tissue RNA - pons [nTPM]":"5.7","Tissue RNA - prostate [nTPM]":"6.3","Tissue RNA - rectum [nTPM]":"3.9","Tissue RNA - retina [nTPM]":"2.9","Tissue RNA - salivary gland [nTPM]":"5.9","Tissue RNA - seminal vesicle [nTPM]":"4.4","Tissue RNA - skeletal muscle [nTPM]":"5.5","Tissue RNA - skin 1 [nTPM]":"7.2","Tissue RNA - small intestine [nTPM]":"7.4","Tissue RNA - smooth muscle [nTPM]":"3.1","Tissue RNA - spinal cord [nTPM]":"4.5","Tissue RNA - spleen [nTPM]":"6.4","Tissue RNA - stomach 1 [nTPM]":"6.6","Tissue RNA - testis [nTPM]":"4.5","Tissue RNA - thalamus [nTPM]":"5.7","Tissue RNA - thymus [nTPM]":"3.8","Tissue RNA - thyroid gland [nTPM]":"7.9","Tissue RNA - tongue [nTPM]":"2.3","Tissue RNA - tonsil [nTPM]":"2.8","Tissue RNA - urinary bladder [nTPM]":"4.8","Tissue RNA - vagina [nTPM]":"4.8","Tissue RNA - white matter [nTPM]":"11.1","Cell RNA - A-431 [nTPM]":"3.4","Cell RNA - A549 [nTPM]":"4.6","Cell RNA - AF22 [nTPM]":"2.5","Cell RNA - AN3-CA [nTPM]":"5.8","Cell RNA - ASC diff [nTPM]":"1.5","Cell RNA - ASC TERT1 [nTPM]":"1.8","Cell RNA - BEWO [nTPM]":"10.0","Cell RNA - BJ [nTPM]":"1.8","Cell RNA - BJ hTERT+ [nTPM]":"2.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.0","Cell RNA - CACO-2 [nTPM]":"4.2","Cell RNA - CAPAN-2 [nTPM]":"10.0","Cell RNA - Daudi [nTPM]":"2.3","Cell RNA - EFO-21 [nTPM]":"8.8","Cell RNA - fHDF\/TERT166 [nTPM]":"1.7","Cell RNA - GAMG [nTPM]":"0.7","Cell RNA - HaCaT [nTPM]":"4.8","Cell RNA - HAP1 [nTPM]":"1.8","Cell RNA - HBEC3-KT [nTPM]":"4.7","Cell RNA - HBF TERT88 [nTPM]":"1.6","Cell RNA - HDLM-2 [nTPM]":"4.4","Cell RNA - HEK 293 [nTPM]":"6.5","Cell RNA - HEL [nTPM]":"2.9","Cell RNA - HeLa [nTPM]":"8.9","Cell RNA - Hep G2 [nTPM]":"4.5","Cell RNA - HHSteC [nTPM]":"3.7","Cell RNA - HL-60 [nTPM]":"3.8","Cell RNA - HMC-1 [nTPM]":"2.3","Cell RNA - HSkMC [nTPM]":"3.0","Cell RNA - hTCEpi [nTPM]":"5.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.1","Cell RNA - hTERT-HME1 [nTPM]":"4.4","Cell RNA - hTERT-RPE1 [nTPM]":"3.3","Cell RNA - HUVEC TERT2 [nTPM]":"4.3","Cell RNA - JURKAT [nTPM]":"4.6","Cell RNA - K-562 [nTPM]":"5.9","Cell RNA - Karpas-707 [nTPM]":"2.6","Cell RNA - LHCN-M2 [nTPM]":"1.8","Cell RNA - MCF7 [nTPM]":"10.3","Cell RNA - MOLT-4 [nTPM]":"4.6","Cell RNA - NB-4 [nTPM]":"9.2","Cell RNA - NTERA-2 [nTPM]":"1.6","Cell RNA - OE19 [nTPM]":"5.5","Cell RNA - PC-3 [nTPM]":"2.7","Cell RNA - REH [nTPM]":"7.0","Cell RNA - RH-30 [nTPM]":"0.6","Cell RNA - RPMI-8226 [nTPM]":"10.4","Cell RNA - RPTEC TERT1 [nTPM]":"5.9","Cell RNA - RT4 [nTPM]":"5.5","Cell RNA - SCLC-21H [nTPM]":"4.0","Cell RNA - SH-SY5Y [nTPM]":"5.3","Cell RNA - SiHa [nTPM]":"10.1","Cell RNA - SK-BR-3 [nTPM]":"3.7","Cell RNA - SK-MEL-30 [nTPM]":"5.3","Cell RNA - SuSa [nTPM]":"1.9","Cell RNA - T-47d [nTPM]":"14.8","Cell RNA - THP-1 [nTPM]":"7.5","Cell RNA - TIME [nTPM]":"5.0","Cell RNA - U-138 MG [nTPM]":"1.8","Cell RNA - U-2 OS [nTPM]":"2.4","Cell RNA - U-2197 [nTPM]":"4.0","Cell RNA - U-251 MG [nTPM]":"2.2","Cell RNA - U-266\/70 [nTPM]":"9.5","Cell RNA - U-266\/84 [nTPM]":"5.1","Cell RNA - U-698 [nTPM]":"4.8","Cell RNA - U-87 MG [nTPM]":"3.3","Cell RNA - U-937 [nTPM]":"3.8","Cell RNA - WM-115 [nTPM]":"4.2","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"1.9","Blood RNA - eosinophil [nTPM]":"0.8","Blood RNA - gdT-cell [nTPM]":"1.9","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"1.6","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.9","Blood RNA - myeloid DC [nTPM]":"1.1","Blood RNA - naive B-cell [nTPM]":"1.5","Blood RNA - naive CD4 T-cell [nTPM]":"2.6","Blood RNA - naive CD8 T-cell [nTPM]":"1.2","Blood RNA - neutrophil [nTPM]":"1.6","Blood RNA - NK-cell [nTPM]":"1.2","Blood RNA - non-classical monocyte [nTPM]":"1.2","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"1.4","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"5.4","Brain RNA - basal ganglia [nTPM]":"7.1","Brain RNA - cerebellum [nTPM]":"8.2","Brain RNA - cerebral cortex [nTPM]":"7.7","Brain RNA - hippocampal formation [nTPM]":"5.3","Brain RNA - hypothalamus [nTPM]":"5.0","Brain RNA - medulla oblongata [nTPM]":"6.4","Brain RNA - midbrain [nTPM]":"4.6","Brain RNA - pons [nTPM]":"5.7","Brain RNA - spinal cord [nTPM]":"4.5","Brain RNA - thalamus [nTPM]":"5.7","Brain RNA - white matter [nTPM]":"11.1","Single Cell Type RNA - Adipocytes [nTPM]":"2.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.5","Single Cell Type RNA - dendritic cells [nTPM]":"1.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.2","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"FDFT1","Gene synonym":["SQS"],"Ensembl":"ENSG00000079459","Gene description":"Farnesyl-diphosphate farnesyltransferase 1","Uniprot":["P37268"],"Chromosome":"8","Position":"11795573-11839304","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Multifunctional enzyme","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"479.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Daudi":"133.1","RPMI-8226":"361.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008874"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA008874":"AB_1078844"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.92e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.59e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Tissue RNA - adipose tissue [nTPM]":"69.1","Tissue RNA - adrenal gland [nTPM]":"126.7","Tissue RNA - amygdala [nTPM]":"8.2","Tissue RNA - appendix [nTPM]":"6.7","Tissue RNA - basal ganglia [nTPM]":"14.9","Tissue RNA - bone marrow [nTPM]":"15.0","Tissue RNA - breast [nTPM]":"69.5","Tissue RNA - cerebellum [nTPM]":"13.1","Tissue RNA - cerebral cortex [nTPM]":"11.6","Tissue RNA - cervix [nTPM]":"93.3","Tissue RNA - choroid plexus [nTPM]":"7.4","Tissue RNA - colon [nTPM]":"113.4","Tissue RNA - duodenum [nTPM]":"6.7","Tissue RNA - endometrium 1 [nTPM]":"80.2","Tissue RNA - epididymis [nTPM]":"2.9","Tissue RNA - esophagus [nTPM]":"165.7","Tissue RNA - fallopian tube [nTPM]":"59.4","Tissue RNA - gallbladder [nTPM]":"3.2","Tissue RNA - heart muscle [nTPM]":"62.9","Tissue RNA - hippocampal formation [nTPM]":"10.0","Tissue RNA - hypothalamus [nTPM]":"11.7","Tissue RNA - kidney [nTPM]":"71.3","Tissue RNA - liver [nTPM]":"118.3","Tissue RNA - lung [nTPM]":"88.0","Tissue RNA - lymph node [nTPM]":"6.0","Tissue RNA - medulla oblongata [nTPM]":"29.9","Tissue RNA - midbrain [nTPM]":"14.1","Tissue RNA - ovary [nTPM]":"66.9","Tissue RNA - pancreas [nTPM]":"58.6","Tissue RNA - parathyroid gland [nTPM]":"2.0","Tissue RNA - pituitary gland [nTPM]":"51.2","Tissue RNA - placenta [nTPM]":"4.2","Tissue RNA - pons [nTPM]":"23.1","Tissue RNA - prostate [nTPM]":"64.5","Tissue RNA - rectum [nTPM]":"5.8","Tissue RNA - retina [nTPM]":"5.4","Tissue RNA - salivary gland [nTPM]":"141.7","Tissue RNA - seminal vesicle [nTPM]":"3.1","Tissue RNA - skeletal muscle [nTPM]":"160.3","Tissue RNA - skin 1 [nTPM]":"129.0","Tissue RNA - small intestine [nTPM]":"92.2","Tissue RNA - smooth muscle [nTPM]":"4.9","Tissue RNA - spinal cord [nTPM]":"15.4","Tissue RNA - spleen [nTPM]":"50.4","Tissue RNA - stomach 1 [nTPM]":"113.2","Tissue RNA - testis [nTPM]":"118.7","Tissue RNA - thalamus [nTPM]":"15.3","Tissue RNA - thymus [nTPM]":"3.2","Tissue RNA - thyroid gland [nTPM]":"45.9","Tissue RNA - tongue [nTPM]":"6.9","Tissue RNA - tonsil [nTPM]":"4.5","Tissue RNA - urinary bladder [nTPM]":"70.4","Tissue RNA - vagina [nTPM]":"107.8","Tissue RNA - white matter [nTPM]":"31.9","Cell RNA - A-431 [nTPM]":"19.1","Cell RNA - A549 [nTPM]":"8.1","Cell RNA - AF22 [nTPM]":"28.8","Cell RNA - AN3-CA [nTPM]":"19.4","Cell RNA - ASC diff [nTPM]":"3.8","Cell RNA - ASC TERT1 [nTPM]":"5.7","Cell RNA - BEWO [nTPM]":"10.9","Cell RNA - BJ [nTPM]":"19.2","Cell RNA - BJ hTERT+ [nTPM]":"10.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.6","Cell RNA - CACO-2 [nTPM]":"8.1","Cell RNA - CAPAN-2 [nTPM]":"14.1","Cell RNA - Daudi [nTPM]":"133.1","Cell RNA - EFO-21 [nTPM]":"3.9","Cell RNA - fHDF\/TERT166 [nTPM]":"3.2","Cell RNA - GAMG [nTPM]":"34.6","Cell RNA - HaCaT [nTPM]":"17.8","Cell RNA - HAP1 [nTPM]":"10.6","Cell RNA - HBEC3-KT [nTPM]":"24.7","Cell RNA - HBF TERT88 [nTPM]":"8.2","Cell RNA - HDLM-2 [nTPM]":"13.1","Cell RNA - HEK 293 [nTPM]":"17.2","Cell RNA - HEL [nTPM]":"9.6","Cell RNA - HeLa [nTPM]":"11.1","Cell RNA - Hep G2 [nTPM]":"21.7","Cell RNA - HHSteC [nTPM]":"7.4","Cell RNA - HL-60 [nTPM]":"5.5","Cell RNA - HMC-1 [nTPM]":"13.0","Cell RNA - HSkMC [nTPM]":"11.2","Cell RNA - hTCEpi [nTPM]":"6.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.2","Cell RNA - hTERT-HME1 [nTPM]":"4.7","Cell RNA - hTERT-RPE1 [nTPM]":"5.3","Cell RNA - HUVEC TERT2 [nTPM]":"2.1","Cell RNA - JURKAT [nTPM]":"24.5","Cell RNA - K-562 [nTPM]":"12.1","Cell RNA - Karpas-707 [nTPM]":"60.0","Cell RNA - LHCN-M2 [nTPM]":"4.6","Cell RNA - MCF7 [nTPM]":"11.1","Cell RNA - MOLT-4 [nTPM]":"16.7","Cell RNA - NB-4 [nTPM]":"12.9","Cell RNA - NTERA-2 [nTPM]":"27.1","Cell RNA - OE19 [nTPM]":"9.0","Cell RNA - PC-3 [nTPM]":"5.3","Cell RNA - REH [nTPM]":"14.9","Cell RNA - RH-30 [nTPM]":"11.3","Cell RNA - RPMI-8226 [nTPM]":"361.0","Cell RNA - RPTEC TERT1 [nTPM]":"11.9","Cell RNA - RT4 [nTPM]":"61.5","Cell RNA - SCLC-21H [nTPM]":"9.6","Cell RNA - SH-SY5Y [nTPM]":"11.2","Cell RNA - SiHa [nTPM]":"4.3","Cell RNA - SK-BR-3 [nTPM]":"11.2","Cell RNA - SK-MEL-30 [nTPM]":"35.9","Cell RNA - SuSa [nTPM]":"12.3","Cell RNA - T-47d [nTPM]":"11.6","Cell RNA - THP-1 [nTPM]":"6.8","Cell RNA - TIME [nTPM]":"11.3","Cell RNA - U-138 MG [nTPM]":"5.1","Cell RNA - U-2 OS [nTPM]":"21.6","Cell RNA - U-2197 [nTPM]":"3.1","Cell RNA - U-251 MG [nTPM]":"5.8","Cell RNA - U-266\/70 [nTPM]":"17.0","Cell RNA - U-266\/84 [nTPM]":"30.2","Cell RNA - U-698 [nTPM]":"26.3","Cell RNA - U-87 MG [nTPM]":"7.5","Cell RNA - U-937 [nTPM]":"18.7","Cell RNA - WM-115 [nTPM]":"19.7","Blood RNA - basophil [nTPM]":"52.1","Blood RNA - classical monocyte [nTPM]":"19.5","Blood RNA - eosinophil [nTPM]":"25.5","Blood RNA - gdT-cell [nTPM]":"23.1","Blood RNA - intermediate monocyte [nTPM]":"23.6","Blood RNA - MAIT T-cell [nTPM]":"20.7","Blood RNA - memory B-cell [nTPM]":"60.5","Blood RNA - memory CD4 T-cell [nTPM]":"25.3","Blood RNA - memory CD8 T-cell [nTPM]":"24.5","Blood RNA - myeloid DC [nTPM]":"29.1","Blood RNA - naive B-cell [nTPM]":"45.6","Blood RNA - naive CD4 T-cell [nTPM]":"25.7","Blood RNA - naive CD8 T-cell [nTPM]":"23.3","Blood RNA - neutrophil [nTPM]":"22.3","Blood RNA - NK-cell [nTPM]":"26.7","Blood RNA - non-classical monocyte [nTPM]":"15.1","Blood RNA - plasmacytoid DC [nTPM]":"27.9","Blood RNA - T-reg [nTPM]":"45.7","Blood RNA - total PBMC [nTPM]":"43.9","Brain RNA - amygdala [nTPM]":"8.2","Brain RNA - basal ganglia [nTPM]":"14.9","Brain RNA - cerebellum [nTPM]":"13.1","Brain RNA - cerebral cortex [nTPM]":"11.6","Brain RNA - hippocampal formation [nTPM]":"10.0","Brain RNA - hypothalamus [nTPM]":"11.7","Brain RNA - medulla oblongata [nTPM]":"29.9","Brain RNA - midbrain [nTPM]":"14.1","Brain RNA - pons [nTPM]":"23.1","Brain RNA - spinal cord [nTPM]":"15.4","Brain RNA - thalamus [nTPM]":"15.3","Brain RNA - white matter [nTPM]":"31.9","Single Cell Type RNA - Adipocytes [nTPM]":"31.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"54.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"164.1","Single Cell Type RNA - Astrocytes [nTPM]":"67.6","Single Cell Type RNA - B-cells [nTPM]":"78.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"52.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"94.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"479.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"87.6","Single Cell Type RNA - Bipolar cells [nTPM]":"17.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"79.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"49.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"78.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"101.5","Single Cell Type RNA - Club cells [nTPM]":"325.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"79.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"266.2","Single Cell Type RNA - dendritic cells [nTPM]":"49.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"134.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"88.0","Single Cell Type RNA - Ductal cells [nTPM]":"165.6","Single Cell Type RNA - Early spermatids [nTPM]":"294.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"55.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.9","Single Cell Type RNA - Endothelial cells [nTPM]":"45.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"79.1","Single Cell Type RNA - Erythroid cells [nTPM]":"113.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"29.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"284.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"153.3","Single Cell Type RNA - Fibroblasts [nTPM]":"37.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"64.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"68.1","Single Cell Type RNA - granulocytes [nTPM]":"57.0","Single Cell Type RNA - Granulosa cells [nTPM]":"86.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.1","Single Cell Type RNA - Hepatocytes [nTPM]":"221.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"94.1","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"117.4","Single Cell Type RNA - Ionocytes [nTPM]":"284.8","Single Cell Type RNA - Kupffer cells [nTPM]":"41.9","Single Cell Type RNA - Langerhans cells [nTPM]":"32.2","Single Cell Type RNA - Late spermatids [nTPM]":"228.8","Single Cell Type RNA - Leydig cells [nTPM]":"77.0","Single Cell Type RNA - Macrophages [nTPM]":"54.3","Single Cell Type RNA - Melanocytes [nTPM]":"101.4","Single Cell Type RNA - Microglial cells [nTPM]":"38.4","Single Cell Type RNA - monocytes [nTPM]":"97.1","Single Cell Type RNA - Muller glia cells [nTPM]":"61.9","Single Cell Type RNA - NK-cells [nTPM]":"55.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"30.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"95.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"163.6","Single Cell Type RNA - Paneth cells [nTPM]":"108.4","Single Cell Type RNA - Peritubular cells [nTPM]":"53.4","Single Cell Type RNA - Plasma cells [nTPM]":"50.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"101.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"87.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"74.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"142.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.0","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"74.4","Single Cell Type RNA - Spermatocytes [nTPM]":"215.5","Single Cell Type RNA - Spermatogonia [nTPM]":"76.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"112.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"88.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"175.0","Single Cell Type RNA - T-cells [nTPM]":"55.7","Single Cell Type RNA - Theca cells [nTPM]":"131.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"100.4","Single Cell Type RNA - Urothelial cells [nTPM]":"167.2"},{"Gene":"FDXR","Gene synonym":["ADR","ADXR"],"Ensembl":"ENSG00000161513","Gene description":"Ferredoxin reductase","Uniprot":["P22570"],"Chromosome":"17","Position":"74862497-74873031","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cholesterol metabolism","Electron transport","Lipid metabolism","Steroid metabolism","Sterol metabolism","Transport"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Deafness","Disease variant","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"adrenal gland":"343.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Granulosa cells":"329.3","Theca cells":"794.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"89.5","Hep G2":"173.5"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB008597","CAB009818","HPA044393","HPA053673"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB008597":"AB_1615557","CAB009818":"AB_2102601","HPA044393":"AB_2678927","HPA053673":"AB_2682225"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.38e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.9","Tissue RNA - adrenal gland [nTPM]":"343.1","Tissue RNA - amygdala [nTPM]":"6.9","Tissue RNA - appendix [nTPM]":"2.4","Tissue RNA - basal ganglia [nTPM]":"8.4","Tissue RNA - bone marrow [nTPM]":"2.2","Tissue RNA - breast [nTPM]":"3.8","Tissue RNA - cerebellum [nTPM]":"7.8","Tissue RNA - cerebral cortex [nTPM]":"8.1","Tissue RNA - cervix [nTPM]":"7.8","Tissue RNA - choroid plexus [nTPM]":"8.6","Tissue RNA - colon [nTPM]":"9.7","Tissue RNA - duodenum [nTPM]":"4.6","Tissue RNA - endometrium 1 [nTPM]":"6.7","Tissue RNA - epididymis [nTPM]":"5.1","Tissue RNA - esophagus [nTPM]":"26.0","Tissue RNA - fallopian tube [nTPM]":"12.9","Tissue RNA - gallbladder [nTPM]":"4.1","Tissue RNA - heart muscle [nTPM]":"6.0","Tissue RNA - hippocampal formation [nTPM]":"6.6","Tissue RNA - hypothalamus [nTPM]":"6.7","Tissue RNA - kidney [nTPM]":"6.5","Tissue RNA - liver [nTPM]":"14.9","Tissue RNA - lung [nTPM]":"5.3","Tissue RNA - lymph node [nTPM]":"2.9","Tissue RNA - medulla oblongata [nTPM]":"7.6","Tissue RNA - midbrain [nTPM]":"7.9","Tissue RNA - ovary [nTPM]":"20.5","Tissue RNA - pancreas [nTPM]":"12.9","Tissue RNA - parathyroid gland [nTPM]":"5.9","Tissue RNA - pituitary gland [nTPM]":"4.1","Tissue RNA - placenta [nTPM]":"3.0","Tissue RNA - pons [nTPM]":"7.5","Tissue RNA - prostate [nTPM]":"6.7","Tissue RNA - rectum [nTPM]":"3.2","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"7.1","Tissue RNA - seminal vesicle [nTPM]":"4.4","Tissue RNA - skeletal muscle [nTPM]":"7.7","Tissue RNA - skin 1 [nTPM]":"16.4","Tissue RNA - small intestine [nTPM]":"5.6","Tissue RNA - smooth muscle [nTPM]":"2.3","Tissue RNA - spinal cord [nTPM]":"7.4","Tissue RNA - spleen [nTPM]":"33.9","Tissue RNA - stomach 1 [nTPM]":"7.6","Tissue RNA - testis [nTPM]":"45.6","Tissue RNA - thalamus [nTPM]":"7.0","Tissue RNA - thymus [nTPM]":"4.7","Tissue RNA - thyroid gland [nTPM]":"6.0","Tissue RNA - tongue [nTPM]":"1.7","Tissue RNA - tonsil [nTPM]":"2.5","Tissue RNA - urinary bladder [nTPM]":"6.2","Tissue RNA - vagina [nTPM]":"10.5","Tissue RNA - white matter [nTPM]":"7.5","Cell RNA - A-431 [nTPM]":"12.5","Cell RNA - A549 [nTPM]":"65.6","Cell RNA - AF22 [nTPM]":"9.6","Cell RNA - AN3-CA [nTPM]":"10.8","Cell RNA - ASC diff [nTPM]":"6.8","Cell RNA - ASC TERT1 [nTPM]":"9.1","Cell RNA - BEWO [nTPM]":"89.5","Cell RNA - BJ [nTPM]":"14.8","Cell RNA - BJ hTERT+ [nTPM]":"15.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.1","Cell RNA - CACO-2 [nTPM]":"18.3","Cell RNA - CAPAN-2 [nTPM]":"10.8","Cell RNA - Daudi [nTPM]":"29.6","Cell RNA - EFO-21 [nTPM]":"2.6","Cell RNA - fHDF\/TERT166 [nTPM]":"6.2","Cell RNA - GAMG [nTPM]":"4.8","Cell RNA - HaCaT [nTPM]":"24.9","Cell RNA - HAP1 [nTPM]":"6.9","Cell RNA - HBEC3-KT [nTPM]":"18.4","Cell RNA - HBF TERT88 [nTPM]":"2.5","Cell RNA - HDLM-2 [nTPM]":"27.9","Cell RNA - HEK 293 [nTPM]":"15.2","Cell RNA - HEL [nTPM]":"22.6","Cell RNA - HeLa [nTPM]":"10.6","Cell RNA - Hep G2 [nTPM]":"173.5","Cell RNA - HHSteC [nTPM]":"19.0","Cell RNA - HL-60 [nTPM]":"5.0","Cell RNA - HMC-1 [nTPM]":"75.1","Cell RNA - HSkMC [nTPM]":"29.2","Cell RNA - hTCEpi [nTPM]":"20.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.1","Cell RNA - hTERT-HME1 [nTPM]":"3.1","Cell RNA - hTERT-RPE1 [nTPM]":"7.0","Cell RNA - HUVEC TERT2 [nTPM]":"43.9","Cell RNA - JURKAT [nTPM]":"10.9","Cell RNA - K-562 [nTPM]":"36.1","Cell RNA - Karpas-707 [nTPM]":"4.8","Cell RNA - LHCN-M2 [nTPM]":"13.4","Cell RNA - MCF7 [nTPM]":"53.4","Cell RNA - MOLT-4 [nTPM]":"19.7","Cell RNA - NB-4 [nTPM]":"10.6","Cell RNA - NTERA-2 [nTPM]":"5.5","Cell RNA - OE19 [nTPM]":"11.8","Cell RNA - PC-3 [nTPM]":"14.5","Cell RNA - REH [nTPM]":"10.6","Cell RNA - RH-30 [nTPM]":"16.4","Cell RNA - RPMI-8226 [nTPM]":"16.2","Cell RNA - RPTEC TERT1 [nTPM]":"7.1","Cell RNA - RT4 [nTPM]":"21.0","Cell RNA - SCLC-21H [nTPM]":"5.2","Cell RNA - SH-SY5Y [nTPM]":"12.1","Cell RNA - SiHa [nTPM]":"10.0","Cell RNA - SK-BR-3 [nTPM]":"21.7","Cell RNA - SK-MEL-30 [nTPM]":"11.2","Cell RNA - SuSa [nTPM]":"10.9","Cell RNA - T-47d [nTPM]":"47.4","Cell RNA - THP-1 [nTPM]":"4.7","Cell RNA - TIME [nTPM]":"20.5","Cell RNA - U-138 MG [nTPM]":"5.9","Cell RNA - U-2 OS [nTPM]":"51.9","Cell RNA - U-2197 [nTPM]":"9.4","Cell RNA - U-251 MG [nTPM]":"7.4","Cell RNA - U-266\/70 [nTPM]":"12.7","Cell RNA - U-266\/84 [nTPM]":"2.3","Cell RNA - U-698 [nTPM]":"6.5","Cell RNA - U-87 MG [nTPM]":"16.1","Cell RNA - U-937 [nTPM]":"7.7","Cell RNA - WM-115 [nTPM]":"20.6","Blood RNA - basophil [nTPM]":"1.7","Blood RNA - classical monocyte [nTPM]":"6.0","Blood RNA - eosinophil [nTPM]":"5.0","Blood RNA - gdT-cell [nTPM]":"5.6","Blood RNA - intermediate monocyte [nTPM]":"4.5","Blood RNA - MAIT T-cell [nTPM]":"5.0","Blood RNA - memory B-cell [nTPM]":"4.8","Blood RNA - memory CD4 T-cell [nTPM]":"5.1","Blood RNA - memory CD8 T-cell [nTPM]":"6.8","Blood RNA - myeloid DC [nTPM]":"7.3","Blood RNA - naive B-cell [nTPM]":"2.4","Blood RNA - naive CD4 T-cell [nTPM]":"4.4","Blood RNA - naive CD8 T-cell [nTPM]":"5.4","Blood RNA - neutrophil [nTPM]":"2.0","Blood RNA - NK-cell [nTPM]":"10.3","Blood RNA - non-classical monocyte [nTPM]":"3.4","Blood RNA - plasmacytoid DC [nTPM]":"1.4","Blood RNA - T-reg [nTPM]":"15.4","Blood RNA - total PBMC [nTPM]":"5.2","Brain RNA - amygdala [nTPM]":"6.9","Brain RNA - basal ganglia [nTPM]":"8.4","Brain RNA - cerebellum [nTPM]":"7.8","Brain RNA - cerebral cortex [nTPM]":"8.1","Brain RNA - hippocampal formation [nTPM]":"6.6","Brain RNA - hypothalamus [nTPM]":"6.7","Brain RNA - medulla oblongata [nTPM]":"7.6","Brain RNA - midbrain [nTPM]":"7.9","Brain RNA - pons [nTPM]":"7.5","Brain RNA - spinal cord [nTPM]":"7.4","Brain RNA - thalamus [nTPM]":"7.0","Brain RNA - white matter [nTPM]":"7.5","Single Cell Type RNA - Adipocytes [nTPM]":"4.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.9","Single Cell Type RNA - Astrocytes [nTPM]":"7.5","Single Cell Type RNA - B-cells [nTPM]":"8.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"42.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Bipolar cells [nTPM]":"4.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"23.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"53.2","Single Cell Type RNA - dendritic cells [nTPM]":"2.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.1","Single Cell Type RNA - Early spermatids [nTPM]":"6.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"28.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.3","Single Cell Type RNA - Endothelial cells [nTPM]":"4.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.1","Single Cell Type RNA - Erythroid cells [nTPM]":"4.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.9","Single Cell Type RNA - Fibroblasts [nTPM]":"12.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.5","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"329.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.5","Single Cell Type RNA - Hepatocytes [nTPM]":"13.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.1","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.1","Single Cell Type RNA - Ionocytes [nTPM]":"36.7","Single Cell Type RNA - Kupffer cells [nTPM]":"6.2","Single Cell Type RNA - Langerhans cells [nTPM]":"2.7","Single Cell Type RNA - Late spermatids [nTPM]":"14.9","Single Cell Type RNA - Leydig cells [nTPM]":"5.9","Single Cell Type RNA - Macrophages [nTPM]":"4.6","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"3.9","Single Cell Type RNA - Muller glia cells [nTPM]":"11.4","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.0","Single Cell Type RNA - Paneth cells [nTPM]":"16.9","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"7.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"21.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"73.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.3","Single Cell Type RNA - Spermatocytes [nTPM]":"6.3","Single Cell Type RNA - Spermatogonia [nTPM]":"6.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"33.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"46.1","Single Cell Type RNA - T-cells [nTPM]":"8.6","Single Cell Type RNA - Theca cells [nTPM]":"794.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.3","Single Cell Type RNA - Urothelial cells [nTPM]":"17.4"},{"Gene":"FECH","Gene synonym":[],"Ensembl":"ENSG00000066926","Gene description":"Ferrochelatase","Uniprot":["P22830"],"Chromosome":"18","Position":"57544377-57586702","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Heme biosynthesis","Porphyrin biosynthesis"],"Molecular function":["Lyase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Distal tubular cells":"156.5","Erythroid cells":"479.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"32.7","K-562":"31.4","U-266\/70":"33.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044100","HPA048177"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044100":"AB_2678809","HPA048177":"AB_2680300"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.38e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.3","Tissue RNA - adrenal gland [nTPM]":"14.7","Tissue RNA - amygdala [nTPM]":"5.2","Tissue RNA - appendix [nTPM]":"1.9","Tissue RNA - basal ganglia [nTPM]":"6.3","Tissue RNA - bone marrow [nTPM]":"39.6","Tissue RNA - breast [nTPM]":"8.8","Tissue RNA - cerebellum [nTPM]":"4.7","Tissue RNA - cerebral cortex [nTPM]":"6.3","Tissue RNA - cervix [nTPM]":"7.8","Tissue RNA - choroid plexus [nTPM]":"5.8","Tissue RNA - colon [nTPM]":"10.0","Tissue RNA - duodenum [nTPM]":"1.8","Tissue RNA - endometrium 1 [nTPM]":"9.2","Tissue RNA - epididymis [nTPM]":"2.9","Tissue RNA - esophagus [nTPM]":"12.0","Tissue RNA - fallopian tube [nTPM]":"7.6","Tissue RNA - gallbladder [nTPM]":"2.6","Tissue RNA - heart muscle [nTPM]":"17.0","Tissue RNA - hippocampal formation [nTPM]":"4.8","Tissue RNA - hypothalamus [nTPM]":"5.2","Tissue RNA - kidney [nTPM]":"20.9","Tissue RNA - liver [nTPM]":"22.0","Tissue RNA - lung [nTPM]":"6.5","Tissue RNA - lymph node [nTPM]":"1.9","Tissue RNA - medulla oblongata [nTPM]":"6.3","Tissue RNA - midbrain [nTPM]":"5.3","Tissue RNA - ovary [nTPM]":"8.4","Tissue RNA - pancreas [nTPM]":"9.2","Tissue RNA - parathyroid gland [nTPM]":"4.3","Tissue RNA - pituitary gland [nTPM]":"8.9","Tissue RNA - placenta [nTPM]":"3.2","Tissue RNA - pons [nTPM]":"7.2","Tissue RNA - prostate [nTPM]":"9.5","Tissue RNA - rectum [nTPM]":"2.4","Tissue RNA - retina [nTPM]":"3.6","Tissue RNA - salivary gland [nTPM]":"9.0","Tissue RNA - seminal vesicle [nTPM]":"2.4","Tissue RNA - skeletal muscle [nTPM]":"32.2","Tissue RNA - skin 1 [nTPM]":"8.4","Tissue RNA - small intestine [nTPM]":"7.2","Tissue RNA - smooth muscle [nTPM]":"2.8","Tissue RNA - spinal cord [nTPM]":"5.3","Tissue RNA - spleen [nTPM]":"10.0","Tissue RNA - stomach 1 [nTPM]":"8.4","Tissue RNA - testis [nTPM]":"4.7","Tissue RNA - thalamus [nTPM]":"5.3","Tissue RNA - thymus [nTPM]":"5.0","Tissue RNA - thyroid gland [nTPM]":"9.7","Tissue RNA - tongue [nTPM]":"7.4","Tissue RNA - tonsil [nTPM]":"1.8","Tissue RNA - urinary bladder [nTPM]":"9.9","Tissue RNA - vagina [nTPM]":"8.5","Tissue RNA - white matter [nTPM]":"9.7","Cell RNA - A-431 [nTPM]":"5.3","Cell RNA - A549 [nTPM]":"15.1","Cell RNA - AF22 [nTPM]":"4.3","Cell RNA - AN3-CA [nTPM]":"8.2","Cell RNA - ASC diff [nTPM]":"2.6","Cell RNA - ASC TERT1 [nTPM]":"7.4","Cell RNA - BEWO [nTPM]":"4.2","Cell RNA - BJ [nTPM]":"4.5","Cell RNA - BJ hTERT+ [nTPM]":"3.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.0","Cell RNA - CACO-2 [nTPM]":"7.3","Cell RNA - CAPAN-2 [nTPM]":"3.0","Cell RNA - Daudi [nTPM]":"4.8","Cell RNA - EFO-21 [nTPM]":"4.3","Cell RNA - fHDF\/TERT166 [nTPM]":"6.8","Cell RNA - GAMG [nTPM]":"3.9","Cell RNA - HaCaT [nTPM]":"3.5","Cell RNA - HAP1 [nTPM]":"4.2","Cell RNA - HBEC3-KT [nTPM]":"3.8","Cell RNA - HBF TERT88 [nTPM]":"3.7","Cell RNA - HDLM-2 [nTPM]":"6.6","Cell RNA - HEK 293 [nTPM]":"19.0","Cell RNA - HEL [nTPM]":"29.5","Cell RNA - HeLa [nTPM]":"12.8","Cell RNA - Hep G2 [nTPM]":"10.5","Cell RNA - HHSteC [nTPM]":"4.9","Cell RNA - HL-60 [nTPM]":"17.7","Cell RNA - HMC-1 [nTPM]":"32.7","Cell RNA - HSkMC [nTPM]":"5.4","Cell RNA - hTCEpi [nTPM]":"4.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.0","Cell RNA - hTERT-HME1 [nTPM]":"1.4","Cell RNA - hTERT-RPE1 [nTPM]":"4.2","Cell RNA - HUVEC TERT2 [nTPM]":"5.3","Cell RNA - JURKAT [nTPM]":"8.0","Cell RNA - K-562 [nTPM]":"31.4","Cell RNA - Karpas-707 [nTPM]":"10.9","Cell RNA - LHCN-M2 [nTPM]":"2.1","Cell RNA - MCF7 [nTPM]":"10.1","Cell RNA - MOLT-4 [nTPM]":"7.8","Cell RNA - NB-4 [nTPM]":"3.8","Cell RNA - NTERA-2 [nTPM]":"4.3","Cell RNA - OE19 [nTPM]":"1.9","Cell RNA - PC-3 [nTPM]":"8.7","Cell RNA - REH [nTPM]":"6.3","Cell RNA - RH-30 [nTPM]":"19.7","Cell RNA - RPMI-8226 [nTPM]":"4.7","Cell RNA - RPTEC TERT1 [nTPM]":"8.6","Cell RNA - RT4 [nTPM]":"19.1","Cell RNA - SCLC-21H [nTPM]":"2.5","Cell RNA - SH-SY5Y [nTPM]":"8.4","Cell RNA - SiHa [nTPM]":"4.8","Cell RNA - SK-BR-3 [nTPM]":"7.4","Cell RNA - SK-MEL-30 [nTPM]":"3.4","Cell RNA - SuSa [nTPM]":"2.5","Cell RNA - T-47d [nTPM]":"4.6","Cell RNA - THP-1 [nTPM]":"2.8","Cell RNA - TIME [nTPM]":"6.8","Cell RNA - U-138 MG [nTPM]":"3.3","Cell RNA - U-2 OS [nTPM]":"1.9","Cell RNA - U-2197 [nTPM]":"1.4","Cell RNA - U-251 MG [nTPM]":"3.2","Cell RNA - U-266\/70 [nTPM]":"33.4","Cell RNA - U-266\/84 [nTPM]":"12.4","Cell RNA - U-698 [nTPM]":"6.3","Cell RNA - U-87 MG [nTPM]":"3.5","Cell RNA - U-937 [nTPM]":"5.6","Cell RNA - WM-115 [nTPM]":"3.9","Blood RNA - basophil [nTPM]":"3.7","Blood RNA - classical monocyte [nTPM]":"3.8","Blood RNA - eosinophil [nTPM]":"8.1","Blood RNA - gdT-cell [nTPM]":"4.5","Blood RNA - intermediate monocyte [nTPM]":"5.0","Blood RNA - MAIT T-cell [nTPM]":"3.2","Blood RNA - memory B-cell [nTPM]":"2.4","Blood RNA - memory CD4 T-cell [nTPM]":"3.0","Blood RNA - memory CD8 T-cell [nTPM]":"4.9","Blood RNA - myeloid DC [nTPM]":"6.6","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"2.8","Blood RNA - naive CD8 T-cell [nTPM]":"3.3","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"6.9","Blood RNA - non-classical monocyte [nTPM]":"5.2","Blood RNA - plasmacytoid DC [nTPM]":"4.3","Blood RNA - T-reg [nTPM]":"3.2","Blood RNA - total PBMC [nTPM]":"3.8","Brain RNA - amygdala [nTPM]":"5.2","Brain RNA - basal ganglia [nTPM]":"6.3","Brain RNA - cerebellum [nTPM]":"4.7","Brain RNA - cerebral cortex [nTPM]":"6.3","Brain RNA - hippocampal formation [nTPM]":"4.8","Brain RNA - hypothalamus [nTPM]":"5.2","Brain RNA - medulla oblongata [nTPM]":"6.3","Brain RNA - midbrain [nTPM]":"5.3","Brain RNA - pons [nTPM]":"7.2","Brain RNA - spinal cord [nTPM]":"5.3","Brain RNA - thalamus [nTPM]":"5.3","Brain RNA - white matter [nTPM]":"9.7","Single Cell Type RNA - Adipocytes [nTPM]":"4.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.6","Single Cell Type RNA - Astrocytes [nTPM]":"10.4","Single Cell Type RNA - B-cells [nTPM]":"5.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"3.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"24.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"7.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"36.6","Single Cell Type RNA - dendritic cells [nTPM]":"15.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"156.5","Single Cell Type RNA - Ductal cells [nTPM]":"16.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.9","Single Cell Type RNA - Endothelial cells [nTPM]":"7.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"479.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"20.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"16.5","Single Cell Type RNA - Fibroblasts [nTPM]":"10.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.7","Single Cell Type RNA - granulocytes [nTPM]":"16.5","Single Cell Type RNA - Granulosa cells [nTPM]":"11.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.2","Single Cell Type RNA - Hepatocytes [nTPM]":"26.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"33.4","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.1","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"10.6","Single Cell Type RNA - Langerhans cells [nTPM]":"4.9","Single Cell Type RNA - Late spermatids [nTPM]":"1.1","Single Cell Type RNA - Leydig cells [nTPM]":"9.9","Single Cell Type RNA - Macrophages [nTPM]":"12.7","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"15.4","Single Cell Type RNA - Muller glia cells [nTPM]":"15.1","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"45.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.4","Single Cell Type RNA - Paneth cells [nTPM]":"6.4","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"12.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.8","Single Cell Type RNA - Spermatocytes [nTPM]":"4.1","Single Cell Type RNA - Spermatogonia [nTPM]":"5.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"24.2","Single Cell Type RNA - T-cells [nTPM]":"8.1","Single Cell Type RNA - Theca cells [nTPM]":"19.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.7","Single Cell Type RNA - Urothelial cells [nTPM]":"5.0"},{"Gene":"FES","Gene synonym":["FPS"],"Ensembl":"ENSG00000182511","Gene description":"FES proto-oncogene, tyrosine kinase","Uniprot":["P07332"],"Chromosome":"15","Position":"90883695-90895776","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Proto-oncogene","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"83.4","lymphoid tissue":"110.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"46.8","Hofbauer cells":"48.7","Kupffer cells":"92.3","Macrophages":"51.9","monocytes":"57.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"315.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"162.6","granulocytes":"315.8","monocytes":"151.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"63.5","HL-60":"56.9","HMC-1":"116.6","NB-4":"76.1","THP-1":"110.8","U-937":"48.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001376"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA001376":"AB_1078847"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.78e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Tissue RNA - adipose tissue [nTPM]":"30.8","Tissue RNA - adrenal gland [nTPM]":"8.0","Tissue RNA - amygdala [nTPM]":"9.4","Tissue RNA - appendix [nTPM]":"20.2","Tissue RNA - basal ganglia [nTPM]":"8.8","Tissue RNA - bone marrow [nTPM]":"83.4","Tissue RNA - breast [nTPM]":"21.3","Tissue RNA - cerebellum [nTPM]":"9.6","Tissue RNA - cerebral cortex [nTPM]":"10.8","Tissue RNA - cervix [nTPM]":"18.1","Tissue RNA - choroid plexus [nTPM]":"9.6","Tissue RNA - colon [nTPM]":"12.5","Tissue RNA - duodenum [nTPM]":"5.8","Tissue RNA - endometrium 1 [nTPM]":"15.7","Tissue RNA - epididymis [nTPM]":"2.4","Tissue RNA - esophagus [nTPM]":"5.9","Tissue RNA - fallopian tube [nTPM]":"19.0","Tissue RNA - gallbladder [nTPM]":"14.0","Tissue RNA - heart muscle [nTPM]":"19.6","Tissue RNA - hippocampal formation [nTPM]":"8.3","Tissue RNA - hypothalamus [nTPM]":"8.7","Tissue RNA - kidney [nTPM]":"18.9","Tissue RNA - liver [nTPM]":"25.2","Tissue RNA - lung [nTPM]":"30.9","Tissue RNA - lymph node [nTPM]":"13.8","Tissue RNA - medulla oblongata [nTPM]":"11.1","Tissue RNA - midbrain [nTPM]":"9.2","Tissue RNA - ovary [nTPM]":"13.5","Tissue RNA - pancreas [nTPM]":"7.8","Tissue RNA - parathyroid gland [nTPM]":"2.3","Tissue RNA - pituitary gland [nTPM]":"5.6","Tissue RNA - placenta [nTPM]":"16.3","Tissue RNA - pons [nTPM]":"10.1","Tissue RNA - prostate [nTPM]":"17.9","Tissue RNA - rectum [nTPM]":"4.6","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"58.3","Tissue RNA - seminal vesicle [nTPM]":"8.0","Tissue RNA - skeletal muscle [nTPM]":"6.1","Tissue RNA - skin 1 [nTPM]":"8.0","Tissue RNA - small intestine [nTPM]":"12.5","Tissue RNA - smooth muscle [nTPM]":"10.7","Tissue RNA - spinal cord [nTPM]":"10.4","Tissue RNA - spleen [nTPM]":"110.9","Tissue RNA - stomach 1 [nTPM]":"9.6","Tissue RNA - testis [nTPM]":"4.5","Tissue RNA - thalamus [nTPM]":"10.9","Tissue RNA - thymus [nTPM]":"4.2","Tissue RNA - thyroid gland [nTPM]":"16.0","Tissue RNA - tongue [nTPM]":"7.0","Tissue RNA - tonsil [nTPM]":"5.7","Tissue RNA - urinary bladder [nTPM]":"15.1","Tissue RNA - vagina [nTPM]":"13.5","Tissue RNA - white matter [nTPM]":"9.8","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"0.8","Cell RNA - AN3-CA [nTPM]":"10.3","Cell RNA - ASC diff [nTPM]":"3.1","Cell RNA - ASC TERT1 [nTPM]":"8.8","Cell RNA - BEWO [nTPM]":"17.9","Cell RNA - BJ [nTPM]":"2.9","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.9","Cell RNA - CACO-2 [nTPM]":"2.6","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"6.8","Cell RNA - EFO-21 [nTPM]":"0.5","Cell RNA - fHDF\/TERT166 [nTPM]":"6.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"1.5","Cell RNA - HAP1 [nTPM]":"1.7","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"1.6","Cell RNA - HDLM-2 [nTPM]":"3.3","Cell RNA - HEK 293 [nTPM]":"1.1","Cell RNA - HEL [nTPM]":"63.5","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"11.9","Cell RNA - HHSteC [nTPM]":"6.8","Cell RNA - HL-60 [nTPM]":"56.9","Cell RNA - HMC-1 [nTPM]":"116.6","Cell RNA - HSkMC [nTPM]":"8.8","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.6","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"31.2","Cell RNA - JURKAT [nTPM]":"9.4","Cell RNA - K-562 [nTPM]":"1.8","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"21.3","Cell RNA - MOLT-4 [nTPM]":"1.8","Cell RNA - NB-4 [nTPM]":"76.1","Cell RNA - NTERA-2 [nTPM]":"3.2","Cell RNA - OE19 [nTPM]":"2.5","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"8.6","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"2.8","Cell RNA - SK-MEL-30 [nTPM]":"2.3","Cell RNA - SuSa [nTPM]":"2.9","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"110.8","Cell RNA - TIME [nTPM]":"24.9","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"10.4","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"8.0","Cell RNA - U-698 [nTPM]":"2.5","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"48.0","Cell RNA - WM-115 [nTPM]":"2.4","Blood RNA - basophil [nTPM]":"64.4","Blood RNA - classical monocyte [nTPM]":"151.7","Blood RNA - eosinophil [nTPM]":"315.8","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"88.6","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"5.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"162.6","Blood RNA - naive B-cell [nTPM]":"4.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"100.5","Blood RNA - NK-cell [nTPM]":"51.4","Blood RNA - non-classical monocyte [nTPM]":"39.8","Blood RNA - plasmacytoid DC [nTPM]":"65.0","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"81.5","Brain RNA - amygdala [nTPM]":"9.4","Brain RNA - basal ganglia [nTPM]":"8.8","Brain RNA - cerebellum [nTPM]":"9.6","Brain RNA - cerebral cortex [nTPM]":"10.8","Brain RNA - hippocampal formation [nTPM]":"8.3","Brain RNA - hypothalamus [nTPM]":"8.7","Brain RNA - medulla oblongata [nTPM]":"11.1","Brain RNA - midbrain [nTPM]":"9.2","Brain RNA - pons [nTPM]":"10.1","Brain RNA - spinal cord [nTPM]":"10.4","Brain RNA - thalamus [nTPM]":"10.9","Brain RNA - white matter [nTPM]":"9.8","Single Cell Type RNA - Adipocytes [nTPM]":"46.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.8","Single Cell Type RNA - Astrocytes [nTPM]":"3.6","Single Cell Type RNA - B-cells [nTPM]":"5.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"0.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.3","Single Cell Type RNA - dendritic cells [nTPM]":"25.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.2","Single Cell Type RNA - Endothelial cells [nTPM]":"29.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"8.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.2","Single Cell Type RNA - Fibroblasts [nTPM]":"9.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.2","Single Cell Type RNA - granulocytes [nTPM]":"29.2","Single Cell Type RNA - Granulosa cells [nTPM]":"10.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.0","Single Cell Type RNA - Hepatocytes [nTPM]":"15.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"48.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"92.3","Single Cell Type RNA - Langerhans cells [nTPM]":"27.9","Single Cell Type RNA - Late spermatids [nTPM]":"8.4","Single Cell Type RNA - Leydig cells [nTPM]":"9.0","Single Cell Type RNA - Macrophages [nTPM]":"51.9","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"57.8","Single Cell Type RNA - Muller glia cells [nTPM]":"2.5","Single Cell Type RNA - NK-cells [nTPM]":"26.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.1","Single Cell Type RNA - Paneth cells [nTPM]":"2.0","Single Cell Type RNA - Peritubular cells [nTPM]":"10.1","Single Cell Type RNA - Plasma cells [nTPM]":"4.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.9","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.9","Single Cell Type RNA - Spermatocytes [nTPM]":"4.4","Single Cell Type RNA - Spermatogonia [nTPM]":"15.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.5","Single Cell Type RNA - T-cells [nTPM]":"6.7","Single Cell Type RNA - Theca cells [nTPM]":"3.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.7","Single Cell Type RNA - Urothelial cells [nTPM]":"5.2"},{"Gene":"FGF23","Gene synonym":[],"Ensembl":"ENSG00000118972","Gene description":"Fibroblast growth factor 23","Uniprot":["Q9GZV9"],"Chromosome":"12","Position":"4368227-4379712","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted secreted proteins","RAS pathway related proteins","Transporters"],"Biological process":["Differentiation"],"Molecular function":["Growth factor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"23","RNA tissue specific nTPM":{"brain":"126.3","choroid plexus":"104.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"10.4","Early spermatids":"6.6","Hepatic stellate cells":"13.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"10.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"10.8"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"1.9","HBEC3-KT":"1.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":56800,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 23: Spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"74.8","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"73.5","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"73.8","Tissue RNA - cerebral cortex [nTPM]":"126.3","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"104.9","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"1.2","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"5.0","Tissue RNA - hippocampal formation [nTPM]":"74.1","Tissue RNA - hypothalamus [nTPM]":"74.1","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"4.1","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"73.8","Tissue RNA - midbrain [nTPM]":"86.6","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"77.8","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.6","Tissue RNA - retina [nTPM]":"2.3","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"1.2","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"72.9","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"73.3","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"0.6","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"78.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"1.9","Cell RNA - AN3-CA [nTPM]":"0.6","Cell RNA - ASC diff [nTPM]":"0.9","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"0.7","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.3","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"1.4","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.5","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.5","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.9","Cell RNA - hTERT-HME1 [nTPM]":"1.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.4","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.7","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"10.8","Blood RNA - classical monocyte [nTPM]":"1.4","Blood RNA - eosinophil [nTPM]":"2.0","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"1.9","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"1.2","Blood RNA - myeloid DC [nTPM]":"1.2","Blood RNA - naive B-cell [nTPM]":"1.9","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.7","Blood RNA - neutrophil [nTPM]":"4.8","Blood RNA - NK-cell [nTPM]":"2.2","Blood RNA - non-classical monocyte [nTPM]":"2.5","Blood RNA - plasmacytoid DC [nTPM]":"1.9","Blood RNA - T-reg [nTPM]":"1.6","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"74.8","Brain RNA - basal ganglia [nTPM]":"73.5","Brain RNA - cerebellum [nTPM]":"73.8","Brain RNA - cerebral cortex [nTPM]":"126.3","Brain RNA - hippocampal formation [nTPM]":"74.1","Brain RNA - hypothalamus [nTPM]":"74.1","Brain RNA - medulla oblongata [nTPM]":"73.8","Brain RNA - midbrain [nTPM]":"86.6","Brain RNA - pons [nTPM]":"77.8","Brain RNA - spinal cord [nTPM]":"72.9","Brain RNA - thalamus [nTPM]":"73.3","Brain RNA - white matter [nTPM]":"78.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"6.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"FGR","Gene synonym":["c-fgr","p55c-fgr","SRC2"],"Ensembl":"ENSG00000000938","Gene description":"FGR proto-oncogene, Src family tyrosine kinase","Uniprot":["P09769"],"Chromosome":"1","Position":"27612064-27635185","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Immunity","Innate immunity"],"Molecular function":["Kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"bone marrow":"207.8","lung":"86.5","lymphoid tissue":"141.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Kupffer cells":"182.2","Langerhans cells":"63.8","Macrophages":"155.9","monocytes":"159.7","NK-cells":"259.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Daudi":"86.0","U-266\/70":"153.1"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002024"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Aggresome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Aggresome"],"Antibody RRID":{"HPA002024":"AB_1078503"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.74e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.12e-3"},"Tissue RNA - adipose tissue [nTPM]":"25.0","Tissue RNA - adrenal gland [nTPM]":"6.8","Tissue RNA - amygdala [nTPM]":"12.8","Tissue RNA - appendix [nTPM]":"62.2","Tissue RNA - basal ganglia [nTPM]":"11.9","Tissue RNA - bone marrow [nTPM]":"207.8","Tissue RNA - breast [nTPM]":"16.0","Tissue RNA - cerebellum [nTPM]":"11.9","Tissue RNA - cerebral cortex [nTPM]":"19.1","Tissue RNA - cervix [nTPM]":"7.6","Tissue RNA - choroid plexus [nTPM]":"11.5","Tissue RNA - colon [nTPM]":"6.0","Tissue RNA - duodenum [nTPM]":"3.9","Tissue RNA - endometrium 1 [nTPM]":"8.1","Tissue RNA - epididymis [nTPM]":"1.7","Tissue RNA - esophagus [nTPM]":"5.2","Tissue RNA - fallopian tube [nTPM]":"15.6","Tissue RNA - gallbladder [nTPM]":"12.7","Tissue RNA - heart muscle [nTPM]":"8.7","Tissue RNA - hippocampal formation [nTPM]":"11.4","Tissue RNA - hypothalamus [nTPM]":"12.3","Tissue RNA - kidney [nTPM]":"7.5","Tissue RNA - liver [nTPM]":"10.8","Tissue RNA - lung [nTPM]":"86.5","Tissue RNA - lymph node [nTPM]":"27.5","Tissue RNA - medulla oblongata [nTPM]":"13.6","Tissue RNA - midbrain [nTPM]":"12.7","Tissue RNA - ovary [nTPM]":"2.9","Tissue RNA - pancreas [nTPM]":"5.8","Tissue RNA - parathyroid gland [nTPM]":"1.6","Tissue RNA - pituitary gland [nTPM]":"2.7","Tissue RNA - placenta [nTPM]":"7.9","Tissue RNA - pons [nTPM]":"14.5","Tissue RNA - prostate [nTPM]":"7.2","Tissue RNA - rectum [nTPM]":"4.0","Tissue RNA - retina [nTPM]":"0.7","Tissue RNA - salivary gland [nTPM]":"6.6","Tissue RNA - seminal vesicle [nTPM]":"2.4","Tissue RNA - skeletal muscle [nTPM]":"3.2","Tissue RNA - skin 1 [nTPM]":"4.5","Tissue RNA - small intestine [nTPM]":"10.1","Tissue RNA - smooth muscle [nTPM]":"16.3","Tissue RNA - spinal cord [nTPM]":"12.5","Tissue RNA - spleen [nTPM]":"141.1","Tissue RNA - stomach 1 [nTPM]":"5.9","Tissue RNA - testis [nTPM]":"2.5","Tissue RNA - thalamus [nTPM]":"17.2","Tissue RNA - thymus [nTPM]":"8.4","Tissue RNA - thyroid gland [nTPM]":"7.4","Tissue RNA - tongue [nTPM]":"6.5","Tissue RNA - tonsil [nTPM]":"20.0","Tissue RNA - urinary bladder [nTPM]":"17.8","Tissue RNA - vagina [nTPM]":"7.3","Tissue RNA - white matter [nTPM]":"12.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.5","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"86.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.7","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"1.7","Cell RNA - HMC-1 [nTPM]":"29.3","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"3.8","Cell RNA - NB-4 [nTPM]":"5.2","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"1.7","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"10.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"153.1","Cell RNA - U-266\/84 [nTPM]":"2.1","Cell RNA - U-698 [nTPM]":"6.5","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"19.5","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"30.8","Blood RNA - classical monocyte [nTPM]":"381.4","Blood RNA - eosinophil [nTPM]":"229.4","Blood RNA - gdT-cell [nTPM]":"189.5","Blood RNA - intermediate monocyte [nTPM]":"469.1","Blood RNA - MAIT T-cell [nTPM]":"11.3","Blood RNA - memory B-cell [nTPM]":"54.0","Blood RNA - memory CD4 T-cell [nTPM]":"15.8","Blood RNA - memory CD8 T-cell [nTPM]":"89.1","Blood RNA - myeloid DC [nTPM]":"196.1","Blood RNA - naive B-cell [nTPM]":"84.0","Blood RNA - naive CD4 T-cell [nTPM]":"8.0","Blood RNA - naive CD8 T-cell [nTPM]":"78.4","Blood RNA - neutrophil [nTPM]":"272.9","Blood RNA - NK-cell [nTPM]":"264.5","Blood RNA - non-classical monocyte [nTPM]":"405.2","Blood RNA - plasmacytoid DC [nTPM]":"9.0","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"494.1","Brain RNA - amygdala [nTPM]":"12.8","Brain RNA - basal ganglia [nTPM]":"11.9","Brain RNA - cerebellum [nTPM]":"11.9","Brain RNA - cerebral cortex [nTPM]":"19.1","Brain RNA - hippocampal formation [nTPM]":"11.4","Brain RNA - hypothalamus [nTPM]":"12.3","Brain RNA - medulla oblongata [nTPM]":"13.6","Brain RNA - midbrain [nTPM]":"12.7","Brain RNA - pons [nTPM]":"14.5","Brain RNA - spinal cord [nTPM]":"12.5","Brain RNA - thalamus [nTPM]":"17.2","Brain RNA - white matter [nTPM]":"12.6","Single Cell Type RNA - Adipocytes [nTPM]":"8.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"24.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"5.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"55.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"14.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"2.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"13.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"1.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"56.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"182.2","Single Cell Type RNA - Langerhans cells [nTPM]":"63.8","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"155.9","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"159.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"259.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"4.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"28.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"2.5"},{"Gene":"FH","Gene synonym":[],"Ensembl":"ENSG00000091483","Gene description":"Fumarate hydratase","Uniprot":["P07954"],"Chromosome":"1","Position":"241497603-241519755","Protein class":["Cancer-related genes","Citric acid cycle related proteins","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Tricarboxylic acid cycle"],"Molecular function":["Lyase"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"276.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"173.5","Early spermatids":"226.0","Syncytiotrophoblasts":"166.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017785","HPA025770","HPA025948","HPA027341"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1800000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB017785":null,"HPA025770":"AB_10599603","HPA025948":"AB_10602177","HPA027341":"AB_10601222"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.76e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Tissue RNA - adipose tissue [nTPM]":"43.4","Tissue RNA - adrenal gland [nTPM]":"75.2","Tissue RNA - amygdala [nTPM]":"30.4","Tissue RNA - appendix [nTPM]":"31.0","Tissue RNA - basal ganglia [nTPM]":"33.3","Tissue RNA - bone marrow [nTPM]":"31.4","Tissue RNA - breast [nTPM]":"37.3","Tissue RNA - cerebellum [nTPM]":"33.5","Tissue RNA - cerebral cortex [nTPM]":"42.0","Tissue RNA - cervix [nTPM]":"28.9","Tissue RNA - choroid plexus [nTPM]":"43.9","Tissue RNA - colon [nTPM]":"66.8","Tissue RNA - duodenum [nTPM]":"68.2","Tissue RNA - endometrium 1 [nTPM]":"36.9","Tissue RNA - epididymis [nTPM]":"26.1","Tissue RNA - esophagus [nTPM]":"51.1","Tissue RNA - fallopian tube [nTPM]":"27.9","Tissue RNA - gallbladder [nTPM]":"23.7","Tissue RNA - heart muscle [nTPM]":"179.0","Tissue RNA - hippocampal formation [nTPM]":"33.9","Tissue RNA - hypothalamus [nTPM]":"33.1","Tissue RNA - kidney [nTPM]":"101.8","Tissue RNA - liver [nTPM]":"276.4","Tissue RNA - lung [nTPM]":"26.4","Tissue RNA - lymph node [nTPM]":"30.0","Tissue RNA - medulla oblongata [nTPM]":"31.8","Tissue RNA - midbrain [nTPM]":"31.0","Tissue RNA - ovary [nTPM]":"24.9","Tissue RNA - pancreas [nTPM]":"38.1","Tissue RNA - parathyroid gland [nTPM]":"95.0","Tissue RNA - pituitary gland [nTPM]":"31.1","Tissue RNA - placenta [nTPM]":"32.1","Tissue RNA - pons [nTPM]":"32.1","Tissue RNA - prostate [nTPM]":"33.5","Tissue RNA - rectum [nTPM]":"69.0","Tissue RNA - retina [nTPM]":"58.8","Tissue RNA - salivary gland [nTPM]":"42.0","Tissue RNA - seminal vesicle [nTPM]":"38.4","Tissue RNA - skeletal muscle [nTPM]":"213.4","Tissue RNA - skin 1 [nTPM]":"40.3","Tissue RNA - small intestine [nTPM]":"59.1","Tissue RNA - smooth muscle [nTPM]":"42.0","Tissue RNA - spinal cord [nTPM]":"32.4","Tissue RNA - spleen [nTPM]":"30.1","Tissue RNA - stomach 1 [nTPM]":"53.6","Tissue RNA - testis [nTPM]":"44.4","Tissue RNA - thalamus [nTPM]":"32.7","Tissue RNA - thymus [nTPM]":"31.3","Tissue RNA - thyroid gland [nTPM]":"34.6","Tissue RNA - tongue [nTPM]":"229.3","Tissue RNA - tonsil [nTPM]":"40.4","Tissue RNA - urinary bladder [nTPM]":"37.5","Tissue RNA - vagina [nTPM]":"33.7","Tissue RNA - white matter [nTPM]":"33.0","Cell RNA - A-431 [nTPM]":"129.2","Cell RNA - A549 [nTPM]":"105.6","Cell RNA - AF22 [nTPM]":"97.9","Cell RNA - AN3-CA [nTPM]":"89.0","Cell RNA - ASC diff [nTPM]":"93.9","Cell RNA - ASC TERT1 [nTPM]":"110.0","Cell RNA - BEWO [nTPM]":"154.9","Cell RNA - BJ [nTPM]":"155.7","Cell RNA - BJ hTERT+ [nTPM]":"121.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"171.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"107.1","Cell RNA - CACO-2 [nTPM]":"152.2","Cell RNA - CAPAN-2 [nTPM]":"78.0","Cell RNA - Daudi [nTPM]":"81.1","Cell RNA - EFO-21 [nTPM]":"100.3","Cell RNA - fHDF\/TERT166 [nTPM]":"119.9","Cell RNA - GAMG [nTPM]":"75.0","Cell RNA - HaCaT [nTPM]":"178.4","Cell RNA - HAP1 [nTPM]":"151.7","Cell RNA - HBEC3-KT [nTPM]":"115.8","Cell RNA - HBF TERT88 [nTPM]":"148.4","Cell RNA - HDLM-2 [nTPM]":"93.5","Cell RNA - HEK 293 [nTPM]":"48.9","Cell RNA - HEL [nTPM]":"76.3","Cell RNA - HeLa [nTPM]":"102.2","Cell RNA - Hep G2 [nTPM]":"131.4","Cell RNA - HHSteC [nTPM]":"84.1","Cell RNA - HL-60 [nTPM]":"180.2","Cell RNA - HMC-1 [nTPM]":"66.7","Cell RNA - HSkMC [nTPM]":"80.2","Cell RNA - hTCEpi [nTPM]":"70.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"96.6","Cell RNA - hTERT-HME1 [nTPM]":"108.0","Cell RNA - hTERT-RPE1 [nTPM]":"60.2","Cell RNA - HUVEC TERT2 [nTPM]":"107.2","Cell RNA - JURKAT [nTPM]":"175.8","Cell RNA - K-562 [nTPM]":"236.3","Cell RNA - Karpas-707 [nTPM]":"101.7","Cell RNA - LHCN-M2 [nTPM]":"126.9","Cell RNA - MCF7 [nTPM]":"64.3","Cell RNA - MOLT-4 [nTPM]":"156.6","Cell RNA - NB-4 [nTPM]":"120.1","Cell RNA - NTERA-2 [nTPM]":"104.5","Cell RNA - OE19 [nTPM]":"186.2","Cell RNA - PC-3 [nTPM]":"223.6","Cell RNA - REH [nTPM]":"127.4","Cell RNA - RH-30 [nTPM]":"107.2","Cell RNA - RPMI-8226 [nTPM]":"365.7","Cell RNA - RPTEC TERT1 [nTPM]":"167.4","Cell RNA - RT4 [nTPM]":"107.6","Cell RNA - SCLC-21H [nTPM]":"125.4","Cell RNA - SH-SY5Y [nTPM]":"108.4","Cell RNA - SiHa [nTPM]":"131.1","Cell RNA - SK-BR-3 [nTPM]":"153.3","Cell RNA - SK-MEL-30 [nTPM]":"104.0","Cell RNA - SuSa [nTPM]":"67.2","Cell RNA - T-47d [nTPM]":"117.1","Cell RNA - THP-1 [nTPM]":"120.9","Cell RNA - TIME [nTPM]":"106.5","Cell RNA - U-138 MG [nTPM]":"76.6","Cell RNA - U-2 OS [nTPM]":"98.9","Cell RNA - U-2197 [nTPM]":"137.0","Cell RNA - U-251 MG [nTPM]":"264.0","Cell RNA - U-266\/70 [nTPM]":"90.3","Cell RNA - U-266\/84 [nTPM]":"103.7","Cell RNA - U-698 [nTPM]":"97.3","Cell RNA - U-87 MG [nTPM]":"85.7","Cell RNA - U-937 [nTPM]":"203.5","Cell RNA - WM-115 [nTPM]":"112.6","Blood RNA - basophil [nTPM]":"11.9","Blood RNA - classical monocyte [nTPM]":"22.8","Blood RNA - eosinophil [nTPM]":"4.9","Blood RNA - gdT-cell [nTPM]":"16.1","Blood RNA - intermediate monocyte [nTPM]":"33.3","Blood RNA - MAIT T-cell [nTPM]":"21.0","Blood RNA - memory B-cell [nTPM]":"27.2","Blood RNA - memory CD4 T-cell [nTPM]":"18.8","Blood RNA - memory CD8 T-cell [nTPM]":"15.1","Blood RNA - myeloid DC [nTPM]":"46.7","Blood RNA - naive B-cell [nTPM]":"25.1","Blood RNA - naive CD4 T-cell [nTPM]":"22.3","Blood RNA - naive CD8 T-cell [nTPM]":"21.1","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"18.3","Blood RNA - non-classical monocyte [nTPM]":"29.1","Blood RNA - plasmacytoid DC [nTPM]":"23.1","Blood RNA - T-reg [nTPM]":"23.8","Blood RNA - total PBMC [nTPM]":"16.7","Brain RNA - amygdala [nTPM]":"30.4","Brain RNA - basal ganglia [nTPM]":"33.3","Brain RNA - cerebellum [nTPM]":"33.5","Brain RNA - cerebral cortex [nTPM]":"42.0","Brain RNA - hippocampal formation [nTPM]":"33.9","Brain RNA - hypothalamus [nTPM]":"33.1","Brain RNA - medulla oblongata [nTPM]":"31.8","Brain RNA - midbrain [nTPM]":"31.0","Brain RNA - pons [nTPM]":"32.1","Brain RNA - spinal cord [nTPM]":"32.4","Brain RNA - thalamus [nTPM]":"32.7","Brain RNA - white matter [nTPM]":"33.0","Single Cell Type RNA - Adipocytes [nTPM]":"17.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"30.2","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"25.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"69.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Bipolar cells [nTPM]":"24.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"173.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"35.8","Single Cell Type RNA - Club cells [nTPM]":"40.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"101.6","Single Cell Type RNA - dendritic cells [nTPM]":"13.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"78.2","Single Cell Type RNA - Ductal cells [nTPM]":"60.4","Single Cell Type RNA - Early spermatids [nTPM]":"226.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.5","Single Cell Type RNA - Endothelial cells [nTPM]":"18.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.0","Single Cell Type RNA - Erythroid cells [nTPM]":"37.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"45.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"58.7","Single Cell Type RNA - Fibroblasts [nTPM]":"25.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"26.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.4","Single Cell Type RNA - granulocytes [nTPM]":"19.0","Single Cell Type RNA - Granulosa cells [nTPM]":"24.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"80.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"50.7","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"40.6","Single Cell Type RNA - Ionocytes [nTPM]":"48.8","Single Cell Type RNA - Kupffer cells [nTPM]":"18.5","Single Cell Type RNA - Langerhans cells [nTPM]":"14.4","Single Cell Type RNA - Late spermatids [nTPM]":"37.4","Single Cell Type RNA - Leydig cells [nTPM]":"23.9","Single Cell Type RNA - Macrophages [nTPM]":"23.9","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"27.9","Single Cell Type RNA - Muller glia cells [nTPM]":"35.0","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.4","Single Cell Type RNA - Paneth cells [nTPM]":"35.7","Single Cell Type RNA - Peritubular cells [nTPM]":"26.7","Single Cell Type RNA - Plasma cells [nTPM]":"41.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"66.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"86.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"39.1","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"67.9","Single Cell Type RNA - Spermatocytes [nTPM]":"84.7","Single Cell Type RNA - Spermatogonia [nTPM]":"47.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"32.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"166.1","Single Cell Type RNA - T-cells [nTPM]":"14.9","Single Cell Type RNA - Theca cells [nTPM]":"48.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"74.2","Single Cell Type RNA - Urothelial cells [nTPM]":"22.8"},{"Gene":"FHIT","Gene synonym":["AP3Aase","FRA3B"],"Ensembl":"ENSG00000189283","Gene description":"Fragile histidine triad diadenosine triphosphatase","Uniprot":["P49789"],"Chromosome":"3","Position":"59747277-61251459","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Transcription","Transcription regulation"],"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"94.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"609.8","Inhibitory neurons":"450.5","Microglial cells":"337.3","Oligodendrocyte precursor cells":"1086.7","Oligodendrocytes":"1111.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"naive CD4 T-cell":"87.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"T-cells":"87.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RPMI-8226":"17.5","U-266\/70":"34.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002684","HPA018840","HPA018909"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":["Nucleoli fibrillar center","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB002684":null,"HPA018840":"AB_1848538","HPA018909":"AB_1848537"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.36e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.6","Tissue RNA - adrenal gland [nTPM]":"24.4","Tissue RNA - amygdala [nTPM]":"13.7","Tissue RNA - appendix [nTPM]":"6.2","Tissue RNA - basal ganglia [nTPM]":"18.3","Tissue RNA - bone marrow [nTPM]":"8.0","Tissue RNA - breast [nTPM]":"9.0","Tissue RNA - cerebellum [nTPM]":"13.0","Tissue RNA - cerebral cortex [nTPM]":"17.3","Tissue RNA - cervix [nTPM]":"5.4","Tissue RNA - choroid plexus [nTPM]":"94.0","Tissue RNA - colon [nTPM]":"6.9","Tissue RNA - duodenum [nTPM]":"6.4","Tissue RNA - endometrium 1 [nTPM]":"3.5","Tissue RNA - epididymis [nTPM]":"6.9","Tissue RNA - esophagus [nTPM]":"5.0","Tissue RNA - fallopian tube [nTPM]":"6.6","Tissue RNA - gallbladder [nTPM]":"9.8","Tissue RNA - heart muscle [nTPM]":"15.8","Tissue RNA - hippocampal formation [nTPM]":"19.7","Tissue RNA - hypothalamus [nTPM]":"16.4","Tissue RNA - kidney [nTPM]":"24.9","Tissue RNA - liver [nTPM]":"9.6","Tissue RNA - lung [nTPM]":"4.7","Tissue RNA - lymph node [nTPM]":"7.6","Tissue RNA - medulla oblongata [nTPM]":"18.9","Tissue RNA - midbrain [nTPM]":"17.0","Tissue RNA - ovary [nTPM]":"6.8","Tissue RNA - pancreas [nTPM]":"13.0","Tissue RNA - parathyroid gland [nTPM]":"18.1","Tissue RNA - pituitary gland [nTPM]":"7.9","Tissue RNA - placenta [nTPM]":"3.0","Tissue RNA - pons [nTPM]":"18.9","Tissue RNA - prostate [nTPM]":"5.3","Tissue RNA - rectum [nTPM]":"5.8","Tissue RNA - retina [nTPM]":"7.6","Tissue RNA - salivary gland [nTPM]":"8.5","Tissue RNA - seminal vesicle [nTPM]":"4.7","Tissue RNA - skeletal muscle [nTPM]":"10.6","Tissue RNA - skin 1 [nTPM]":"8.1","Tissue RNA - small intestine [nTPM]":"5.3","Tissue RNA - smooth muscle [nTPM]":"4.7","Tissue RNA - spinal cord [nTPM]":"15.0","Tissue RNA - spleen [nTPM]":"5.0","Tissue RNA - stomach 1 [nTPM]":"8.6","Tissue RNA - testis [nTPM]":"5.5","Tissue RNA - thalamus [nTPM]":"15.9","Tissue RNA - thymus [nTPM]":"12.1","Tissue RNA - thyroid gland [nTPM]":"11.7","Tissue RNA - tongue [nTPM]":"7.2","Tissue RNA - tonsil [nTPM]":"5.3","Tissue RNA - urinary bladder [nTPM]":"6.7","Tissue RNA - vagina [nTPM]":"4.2","Tissue RNA - white matter [nTPM]":"19.8","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"1.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.6","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"2.5","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"2.7","Cell RNA - CAPAN-2 [nTPM]":"4.2","Cell RNA - Daudi [nTPM]":"4.0","Cell RNA - EFO-21 [nTPM]":"0.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"3.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"12.7","Cell RNA - HBEC3-KT [nTPM]":"3.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"2.2","Cell RNA - HEK 293 [nTPM]":"5.0","Cell RNA - HEL [nTPM]":"3.3","Cell RNA - HeLa [nTPM]":"2.0","Cell RNA - Hep G2 [nTPM]":"6.4","Cell RNA - HHSteC [nTPM]":"3.3","Cell RNA - HL-60 [nTPM]":"8.7","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"9.1","Cell RNA - hTCEpi [nTPM]":"5.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"6.9","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"3.7","Cell RNA - K-562 [nTPM]":"2.5","Cell RNA - Karpas-707 [nTPM]":"11.9","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"3.6","Cell RNA - MOLT-4 [nTPM]":"15.2","Cell RNA - NB-4 [nTPM]":"6.7","Cell RNA - NTERA-2 [nTPM]":"1.2","Cell RNA - OE19 [nTPM]":"12.2","Cell RNA - PC-3 [nTPM]":"0.9","Cell RNA - REH [nTPM]":"11.3","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"17.5","Cell RNA - RPTEC TERT1 [nTPM]":"15.3","Cell RNA - RT4 [nTPM]":"2.0","Cell RNA - SCLC-21H [nTPM]":"2.9","Cell RNA - SH-SY5Y [nTPM]":"4.3","Cell RNA - SiHa [nTPM]":"1.5","Cell RNA - SK-BR-3 [nTPM]":"9.9","Cell RNA - SK-MEL-30 [nTPM]":"10.1","Cell RNA - SuSa [nTPM]":"5.3","Cell RNA - T-47d [nTPM]":"0.4","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"1.7","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"2.4","Cell RNA - U-266\/70 [nTPM]":"34.6","Cell RNA - U-266\/84 [nTPM]":"11.3","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"4.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"1.9","Blood RNA - basophil [nTPM]":"6.8","Blood RNA - classical monocyte [nTPM]":"4.6","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"2.2","Blood RNA - intermediate monocyte [nTPM]":"2.9","Blood RNA - MAIT T-cell [nTPM]":"1.4","Blood RNA - memory B-cell [nTPM]":"4.1","Blood RNA - memory CD4 T-cell [nTPM]":"17.2","Blood RNA - memory CD8 T-cell [nTPM]":"1.8","Blood RNA - myeloid DC [nTPM]":"5.7","Blood RNA - naive B-cell [nTPM]":"3.1","Blood RNA - naive CD4 T-cell [nTPM]":"87.6","Blood RNA - naive CD8 T-cell [nTPM]":"15.6","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"7.2","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"5.8","Blood RNA - T-reg [nTPM]":"20.5","Blood RNA - total PBMC [nTPM]":"11.9","Brain RNA - amygdala [nTPM]":"13.7","Brain RNA - basal ganglia [nTPM]":"18.3","Brain RNA - cerebellum [nTPM]":"13.0","Brain RNA - cerebral cortex [nTPM]":"17.3","Brain RNA - hippocampal formation [nTPM]":"19.7","Brain RNA - hypothalamus [nTPM]":"16.4","Brain RNA - medulla oblongata [nTPM]":"18.9","Brain RNA - midbrain [nTPM]":"17.0","Brain RNA - pons [nTPM]":"18.9","Brain RNA - spinal cord [nTPM]":"15.0","Brain RNA - thalamus [nTPM]":"15.9","Brain RNA - white matter [nTPM]":"19.8","Single Cell Type RNA - Adipocytes [nTPM]":"4.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.6","Single Cell Type RNA - Astrocytes [nTPM]":"609.8","Single Cell Type RNA - B-cells [nTPM]":"19.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"46.7","Single Cell Type RNA - Bipolar cells [nTPM]":"12.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"41.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"31.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"17.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"58.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"42.0","Single Cell Type RNA - dendritic cells [nTPM]":"12.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"78.2","Single Cell Type RNA - Ductal cells [nTPM]":"19.1","Single Cell Type RNA - Early spermatids [nTPM]":"45.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.9","Single Cell Type RNA - Endothelial cells [nTPM]":"7.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.7","Single Cell Type RNA - Erythroid cells [nTPM]":"17.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"276.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.5","Single Cell Type RNA - Fibroblasts [nTPM]":"10.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.0","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"25.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"23.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.9","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"450.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.9","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"10.2","Single Cell Type RNA - Langerhans cells [nTPM]":"7.1","Single Cell Type RNA - Late spermatids [nTPM]":"163.0","Single Cell Type RNA - Leydig cells [nTPM]":"19.3","Single Cell Type RNA - Macrophages [nTPM]":"12.9","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"337.3","Single Cell Type RNA - monocytes [nTPM]":"8.6","Single Cell Type RNA - Muller glia cells [nTPM]":"19.7","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1086.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1111.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.7","Single Cell Type RNA - Paneth cells [nTPM]":"15.0","Single Cell Type RNA - Peritubular cells [nTPM]":"9.8","Single Cell Type RNA - Plasma cells [nTPM]":"23.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"126.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"20.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.2","Single Cell Type RNA - Spermatocytes [nTPM]":"19.1","Single Cell Type RNA - Spermatogonia [nTPM]":"7.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"33.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"32.7","Single Cell Type RNA - T-cells [nTPM]":"11.5","Single Cell Type RNA - Theca cells [nTPM]":"23.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.1","Single Cell Type RNA - Urothelial cells [nTPM]":"18.8"},{"Gene":"FITM2","Gene synonym":["C20orf142","dJ881L22.2","FIT2"],"Ensembl":"ENSG00000197296","Gene description":"Fat storage inducing transmembrane protein 2","Uniprot":["Q8N6M3"],"Chromosome":"20","Position":"44302840-44311202","Protein class":["Disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Deafness","Disease variant","Dystonia","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"heart muscle":"67.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Cardiomyocytes":"153.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.98e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-3"},"Tissue RNA - adipose tissue [nTPM]":"11.4","Tissue RNA - adrenal gland [nTPM]":"11.1","Tissue RNA - amygdala [nTPM]":"4.8","Tissue RNA - appendix [nTPM]":"2.9","Tissue RNA - basal ganglia [nTPM]":"5.0","Tissue RNA - bone marrow [nTPM]":"1.2","Tissue RNA - breast [nTPM]":"7.0","Tissue RNA - cerebellum [nTPM]":"5.7","Tissue RNA - cerebral cortex [nTPM]":"6.3","Tissue RNA - cervix [nTPM]":"4.2","Tissue RNA - choroid plexus [nTPM]":"5.9","Tissue RNA - colon [nTPM]":"5.2","Tissue RNA - duodenum [nTPM]":"4.3","Tissue RNA - endometrium 1 [nTPM]":"4.0","Tissue RNA - epididymis [nTPM]":"8.7","Tissue RNA - esophagus [nTPM]":"3.3","Tissue RNA - fallopian tube [nTPM]":"3.7","Tissue RNA - gallbladder [nTPM]":"3.2","Tissue RNA - heart muscle [nTPM]":"67.4","Tissue RNA - hippocampal formation [nTPM]":"4.8","Tissue RNA - hypothalamus [nTPM]":"5.9","Tissue RNA - kidney [nTPM]":"7.9","Tissue RNA - liver [nTPM]":"6.4","Tissue RNA - lung [nTPM]":"4.1","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"6.9","Tissue RNA - midbrain [nTPM]":"5.9","Tissue RNA - ovary [nTPM]":"4.6","Tissue RNA - pancreas [nTPM]":"7.4","Tissue RNA - parathyroid gland [nTPM]":"13.6","Tissue RNA - pituitary gland [nTPM]":"5.2","Tissue RNA - placenta [nTPM]":"1.9","Tissue RNA - pons [nTPM]":"7.4","Tissue RNA - prostate [nTPM]":"6.4","Tissue RNA - rectum [nTPM]":"6.0","Tissue RNA - retina [nTPM]":"6.7","Tissue RNA - salivary gland [nTPM]":"6.5","Tissue RNA - seminal vesicle [nTPM]":"4.4","Tissue RNA - skeletal muscle [nTPM]":"9.2","Tissue RNA - skin 1 [nTPM]":"5.7","Tissue RNA - small intestine [nTPM]":"3.9","Tissue RNA - smooth muscle [nTPM]":"5.3","Tissue RNA - spinal cord [nTPM]":"4.2","Tissue RNA - spleen [nTPM]":"2.6","Tissue RNA - stomach 1 [nTPM]":"4.6","Tissue RNA - testis [nTPM]":"3.8","Tissue RNA - thalamus [nTPM]":"5.4","Tissue RNA - thymus [nTPM]":"1.7","Tissue RNA - thyroid gland [nTPM]":"6.3","Tissue RNA - tongue [nTPM]":"16.8","Tissue RNA - tonsil [nTPM]":"2.6","Tissue RNA - urinary bladder [nTPM]":"4.5","Tissue RNA - vagina [nTPM]":"3.1","Tissue RNA - white matter [nTPM]":"4.7","Cell RNA - A-431 [nTPM]":"7.2","Cell RNA - A549 [nTPM]":"10.9","Cell RNA - AF22 [nTPM]":"4.5","Cell RNA - AN3-CA [nTPM]":"6.6","Cell RNA - ASC diff [nTPM]":"31.4","Cell RNA - ASC TERT1 [nTPM]":"12.8","Cell RNA - BEWO [nTPM]":"4.6","Cell RNA - BJ [nTPM]":"11.5","Cell RNA - BJ hTERT+ [nTPM]":"8.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.9","Cell RNA - CACO-2 [nTPM]":"13.5","Cell RNA - CAPAN-2 [nTPM]":"5.1","Cell RNA - Daudi [nTPM]":"4.9","Cell RNA - EFO-21 [nTPM]":"6.5","Cell RNA - fHDF\/TERT166 [nTPM]":"13.0","Cell RNA - GAMG [nTPM]":"14.3","Cell RNA - HaCaT [nTPM]":"15.8","Cell RNA - HAP1 [nTPM]":"5.7","Cell RNA - HBEC3-KT [nTPM]":"7.7","Cell RNA - HBF TERT88 [nTPM]":"9.6","Cell RNA - HDLM-2 [nTPM]":"1.4","Cell RNA - HEK 293 [nTPM]":"2.7","Cell RNA - HEL [nTPM]":"1.6","Cell RNA - HeLa [nTPM]":"6.5","Cell RNA - Hep G2 [nTPM]":"22.9","Cell RNA - HHSteC [nTPM]":"6.6","Cell RNA - HL-60 [nTPM]":"3.1","Cell RNA - HMC-1 [nTPM]":"4.0","Cell RNA - HSkMC [nTPM]":"9.7","Cell RNA - hTCEpi [nTPM]":"17.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.2","Cell RNA - hTERT-HME1 [nTPM]":"4.7","Cell RNA - hTERT-RPE1 [nTPM]":"4.9","Cell RNA - HUVEC TERT2 [nTPM]":"6.4","Cell RNA - JURKAT [nTPM]":"3.1","Cell RNA - K-562 [nTPM]":"2.7","Cell RNA - Karpas-707 [nTPM]":"14.2","Cell RNA - LHCN-M2 [nTPM]":"9.1","Cell RNA - MCF7 [nTPM]":"22.4","Cell RNA - MOLT-4 [nTPM]":"1.2","Cell RNA - NB-4 [nTPM]":"3.4","Cell RNA - NTERA-2 [nTPM]":"1.1","Cell RNA - OE19 [nTPM]":"10.8","Cell RNA - PC-3 [nTPM]":"13.9","Cell RNA - REH [nTPM]":"1.9","Cell RNA - RH-30 [nTPM]":"8.4","Cell RNA - RPMI-8226 [nTPM]":"4.9","Cell RNA - RPTEC TERT1 [nTPM]":"5.1","Cell RNA - RT4 [nTPM]":"6.7","Cell RNA - SCLC-21H [nTPM]":"2.7","Cell RNA - SH-SY5Y [nTPM]":"3.2","Cell RNA - SiHa [nTPM]":"24.4","Cell RNA - SK-BR-3 [nTPM]":"13.5","Cell RNA - SK-MEL-30 [nTPM]":"10.3","Cell RNA - SuSa [nTPM]":"2.0","Cell RNA - T-47d [nTPM]":"16.5","Cell RNA - THP-1 [nTPM]":"2.4","Cell RNA - TIME [nTPM]":"7.9","Cell RNA - U-138 MG [nTPM]":"28.2","Cell RNA - U-2 OS [nTPM]":"12.6","Cell RNA - U-2197 [nTPM]":"16.6","Cell RNA - U-251 MG [nTPM]":"6.8","Cell RNA - U-266\/70 [nTPM]":"5.2","Cell RNA - U-266\/84 [nTPM]":"14.4","Cell RNA - U-698 [nTPM]":"1.3","Cell RNA - U-87 MG [nTPM]":"12.6","Cell RNA - U-937 [nTPM]":"4.9","Cell RNA - WM-115 [nTPM]":"14.4","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"1.0","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"1.1","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"1.2","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"1.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"1.0","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"2.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.6","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"1.4","Blood RNA - non-classical monocyte [nTPM]":"0.8","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"4.8","Brain RNA - basal ganglia [nTPM]":"5.0","Brain RNA - cerebellum [nTPM]":"5.7","Brain RNA - cerebral cortex [nTPM]":"6.3","Brain RNA - hippocampal formation [nTPM]":"4.8","Brain RNA - hypothalamus [nTPM]":"5.9","Brain RNA - medulla oblongata [nTPM]":"6.9","Brain RNA - midbrain [nTPM]":"5.9","Brain RNA - pons [nTPM]":"7.4","Brain RNA - spinal cord [nTPM]":"4.2","Brain RNA - thalamus [nTPM]":"5.4","Brain RNA - white matter [nTPM]":"4.7","Single Cell Type RNA - Adipocytes [nTPM]":"2.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.7","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"3.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"6.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"153.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"4.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.2","Single Cell Type RNA - Early spermatids [nTPM]":"4.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.0","Single Cell Type RNA - Endothelial cells [nTPM]":"4.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.1","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.5","Single Cell Type RNA - Fibroblasts [nTPM]":"9.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"4.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.2","Single Cell Type RNA - Hepatocytes [nTPM]":"14.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.4","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.8","Single Cell Type RNA - Langerhans cells [nTPM]":"2.2","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"7.8","Single Cell Type RNA - Macrophages [nTPM]":"1.7","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"2.3","Single Cell Type RNA - Muller glia cells [nTPM]":"6.6","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.7","Single Cell Type RNA - Paneth cells [nTPM]":"4.1","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"3.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.3","Single Cell Type RNA - Spermatocytes [nTPM]":"9.1","Single Cell Type RNA - Spermatogonia [nTPM]":"6.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - T-cells [nTPM]":"2.1","Single Cell Type RNA - Theca cells [nTPM]":"16.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.2","Single Cell Type RNA - Urothelial cells [nTPM]":"2.2"},{"Gene":"FKBP10","Gene synonym":["FKBP6","FKBP65","FLJ20683","FLJ22041","FLJ23833","hFKBP65"],"Ensembl":"ENSG00000141756","Gene description":"FKBP prolyl isomerase 10","Uniprot":["Q96AY3"],"Chromosome":"17","Position":"41812680-41823213","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Isomerase","Rotamase"],"Disease involvement":["Disease variant","Osteogenesis imperfecta"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"79.1","Fibroblasts":"100.0","Sertoli cells":"59.2","Smooth muscle cells":"65.3","Theca cells":"54.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"fHDF\/TERT166":"551.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051171","HPA057021"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA051171":"AB_2681371","HPA057021":"AB_2683312"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.16e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.43e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.99e-4"},"Tissue RNA - adipose tissue [nTPM]":"39.4","Tissue RNA - adrenal gland [nTPM]":"39.5","Tissue RNA - amygdala [nTPM]":"20.9","Tissue RNA - appendix [nTPM]":"27.1","Tissue RNA - basal ganglia [nTPM]":"22.2","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"33.5","Tissue RNA - cerebellum [nTPM]":"21.7","Tissue RNA - cerebral cortex [nTPM]":"26.1","Tissue RNA - cervix [nTPM]":"64.0","Tissue RNA - choroid plexus [nTPM]":"22.0","Tissue RNA - colon [nTPM]":"29.1","Tissue RNA - duodenum [nTPM]":"7.6","Tissue RNA - endometrium 1 [nTPM]":"61.5","Tissue RNA - epididymis [nTPM]":"16.9","Tissue RNA - esophagus [nTPM]":"13.9","Tissue RNA - fallopian tube [nTPM]":"50.9","Tissue RNA - gallbladder [nTPM]":"46.0","Tissue RNA - heart muscle [nTPM]":"45.6","Tissue RNA - hippocampal formation [nTPM]":"20.3","Tissue RNA - hypothalamus [nTPM]":"22.1","Tissue RNA - kidney [nTPM]":"17.7","Tissue RNA - liver [nTPM]":"7.8","Tissue RNA - lung [nTPM]":"37.8","Tissue RNA - lymph node [nTPM]":"10.9","Tissue RNA - medulla oblongata [nTPM]":"24.6","Tissue RNA - midbrain [nTPM]":"21.6","Tissue RNA - ovary [nTPM]":"58.4","Tissue RNA - pancreas [nTPM]":"15.1","Tissue RNA - parathyroid gland [nTPM]":"48.5","Tissue RNA - pituitary gland [nTPM]":"56.7","Tissue RNA - placenta [nTPM]":"60.7","Tissue RNA - pons [nTPM]":"22.2","Tissue RNA - prostate [nTPM]":"32.6","Tissue RNA - rectum [nTPM]":"10.8","Tissue RNA - retina [nTPM]":"6.0","Tissue RNA - salivary gland [nTPM]":"14.7","Tissue RNA - seminal vesicle [nTPM]":"30.8","Tissue RNA - skeletal muscle [nTPM]":"7.6","Tissue RNA - skin 1 [nTPM]":"20.4","Tissue RNA - small intestine [nTPM]":"19.1","Tissue RNA - smooth muscle [nTPM]":"55.6","Tissue RNA - spinal cord [nTPM]":"21.9","Tissue RNA - spleen [nTPM]":"14.3","Tissue RNA - stomach 1 [nTPM]":"18.5","Tissue RNA - testis [nTPM]":"9.0","Tissue RNA - thalamus [nTPM]":"24.2","Tissue RNA - thymus [nTPM]":"4.9","Tissue RNA - thyroid gland [nTPM]":"34.9","Tissue RNA - tongue [nTPM]":"9.3","Tissue RNA - tonsil [nTPM]":"4.4","Tissue RNA - urinary bladder [nTPM]":"42.2","Tissue RNA - vagina [nTPM]":"39.1","Tissue RNA - white matter [nTPM]":"21.6","Cell RNA - A-431 [nTPM]":"0.7","Cell RNA - A549 [nTPM]":"119.6","Cell RNA - AF22 [nTPM]":"110.7","Cell RNA - AN3-CA [nTPM]":"363.3","Cell RNA - ASC diff [nTPM]":"379.3","Cell RNA - ASC TERT1 [nTPM]":"441.7","Cell RNA - BEWO [nTPM]":"92.0","Cell RNA - BJ [nTPM]":"490.4","Cell RNA - BJ hTERT+ [nTPM]":"497.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"185.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"159.0","Cell RNA - CACO-2 [nTPM]":"62.1","Cell RNA - CAPAN-2 [nTPM]":"4.8","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"6.6","Cell RNA - fHDF\/TERT166 [nTPM]":"551.9","Cell RNA - GAMG [nTPM]":"45.9","Cell RNA - HaCaT [nTPM]":"0.8","Cell RNA - HAP1 [nTPM]":"66.7","Cell RNA - HBEC3-KT [nTPM]":"133.4","Cell RNA - HBF TERT88 [nTPM]":"77.9","Cell RNA - HDLM-2 [nTPM]":"33.0","Cell RNA - HEK 293 [nTPM]":"99.9","Cell RNA - HEL [nTPM]":"48.6","Cell RNA - HeLa [nTPM]":"132.1","Cell RNA - Hep G2 [nTPM]":"181.0","Cell RNA - HHSteC [nTPM]":"411.4","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"476.1","Cell RNA - hTCEpi [nTPM]":"0.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"150.3","Cell RNA - hTERT-HME1 [nTPM]":"115.5","Cell RNA - hTERT-RPE1 [nTPM]":"352.6","Cell RNA - HUVEC TERT2 [nTPM]":"158.8","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"1.9","Cell RNA - Karpas-707 [nTPM]":"16.7","Cell RNA - LHCN-M2 [nTPM]":"157.0","Cell RNA - MCF7 [nTPM]":"163.2","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"85.4","Cell RNA - OE19 [nTPM]":"258.0","Cell RNA - PC-3 [nTPM]":"38.3","Cell RNA - REH [nTPM]":"9.9","Cell RNA - RH-30 [nTPM]":"125.2","Cell RNA - RPMI-8226 [nTPM]":"15.7","Cell RNA - RPTEC TERT1 [nTPM]":"31.7","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"26.7","Cell RNA - SH-SY5Y [nTPM]":"92.1","Cell RNA - SiHa [nTPM]":"0.7","Cell RNA - SK-BR-3 [nTPM]":"349.3","Cell RNA - SK-MEL-30 [nTPM]":"166.0","Cell RNA - SuSa [nTPM]":"137.4","Cell RNA - T-47d [nTPM]":"54.1","Cell RNA - THP-1 [nTPM]":"3.1","Cell RNA - TIME [nTPM]":"181.0","Cell RNA - U-138 MG [nTPM]":"219.0","Cell RNA - U-2 OS [nTPM]":"111.5","Cell RNA - U-2197 [nTPM]":"145.8","Cell RNA - U-251 MG [nTPM]":"76.0","Cell RNA - U-266\/70 [nTPM]":"0.8","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"299.7","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"213.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"20.9","Brain RNA - basal ganglia [nTPM]":"22.2","Brain RNA - cerebellum [nTPM]":"21.7","Brain RNA - cerebral cortex [nTPM]":"26.1","Brain RNA - hippocampal formation [nTPM]":"20.3","Brain RNA - hypothalamus [nTPM]":"22.1","Brain RNA - medulla oblongata [nTPM]":"24.6","Brain RNA - midbrain [nTPM]":"21.6","Brain RNA - pons [nTPM]":"22.2","Brain RNA - spinal cord [nTPM]":"21.9","Brain RNA - thalamus [nTPM]":"24.2","Brain RNA - white matter [nTPM]":"21.6","Single Cell Type RNA - Adipocytes [nTPM]":"14.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"38.2","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"1.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"8.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"79.1","Single Cell Type RNA - Endothelial cells [nTPM]":"34.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"30.8","Single Cell Type RNA - Fibroblasts [nTPM]":"100.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"32.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"30.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.7","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"9.7","Single Cell Type RNA - Late spermatids [nTPM]":"2.9","Single Cell Type RNA - Leydig cells [nTPM]":"46.9","Single Cell Type RNA - Macrophages [nTPM]":"1.5","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"32.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"44.8","Single Cell Type RNA - Plasma cells [nTPM]":"0.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"35.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"65.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.9","Single Cell Type RNA - Spermatogonia [nTPM]":"7.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.9","Single Cell Type RNA - T-cells [nTPM]":"2.1","Single Cell Type RNA - Theca cells [nTPM]":"54.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"1.6"},{"Gene":"FKBP14","Gene synonym":["FKBP22","FLJ20731"],"Ensembl":"ENSG00000106080","Gene description":"FKBP prolyl isomerase 14","Uniprot":["Q9NWM8"],"Chromosome":"7","Position":"30010587-30026702","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Isomerase","Rotamase"],"Disease involvement":["Deafness","Ehlers-Danlos syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013329","HPA026829"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm","Golgi apparatus"],"Antibody RRID":{"HPA013329":"AB_1848613","HPA026829":"AB_10601651"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.60e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.87e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.57e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.25e-4"},"Tissue RNA - adipose tissue [nTPM]":"6.5","Tissue RNA - adrenal gland [nTPM]":"5.1","Tissue RNA - amygdala [nTPM]":"3.4","Tissue RNA - appendix [nTPM]":"7.0","Tissue RNA - basal ganglia [nTPM]":"3.5","Tissue RNA - bone marrow [nTPM]":"4.3","Tissue RNA - breast [nTPM]":"6.4","Tissue RNA - cerebellum [nTPM]":"5.4","Tissue RNA - cerebral cortex [nTPM]":"3.6","Tissue RNA - cervix [nTPM]":"9.9","Tissue RNA - choroid plexus [nTPM]":"3.1","Tissue RNA - colon [nTPM]":"4.7","Tissue RNA - duodenum [nTPM]":"3.0","Tissue RNA - endometrium 1 [nTPM]":"8.5","Tissue RNA - epididymis [nTPM]":"10.0","Tissue RNA - esophagus [nTPM]":"4.7","Tissue RNA - fallopian tube [nTPM]":"4.3","Tissue RNA - gallbladder [nTPM]":"6.0","Tissue RNA - heart muscle [nTPM]":"6.8","Tissue RNA - hippocampal formation [nTPM]":"3.2","Tissue RNA - hypothalamus [nTPM]":"3.2","Tissue RNA - kidney [nTPM]":"3.1","Tissue RNA - liver [nTPM]":"3.2","Tissue RNA - lung [nTPM]":"4.1","Tissue RNA - lymph node [nTPM]":"3.1","Tissue RNA - medulla oblongata [nTPM]":"3.3","Tissue RNA - midbrain [nTPM]":"3.1","Tissue RNA - ovary [nTPM]":"5.4","Tissue RNA - pancreas [nTPM]":"5.8","Tissue RNA - parathyroid gland [nTPM]":"6.2","Tissue RNA - pituitary gland [nTPM]":"7.7","Tissue RNA - placenta [nTPM]":"7.9","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"6.8","Tissue RNA - rectum [nTPM]":"4.8","Tissue RNA - retina [nTPM]":"7.2","Tissue RNA - salivary gland [nTPM]":"4.3","Tissue RNA - seminal vesicle [nTPM]":"7.5","Tissue RNA - skeletal muscle [nTPM]":"2.1","Tissue RNA - skin 1 [nTPM]":"4.7","Tissue RNA - small intestine [nTPM]":"2.9","Tissue RNA - smooth muscle [nTPM]":"13.9","Tissue RNA - spinal cord [nTPM]":"3.0","Tissue RNA - spleen [nTPM]":"2.7","Tissue RNA - stomach 1 [nTPM]":"4.0","Tissue RNA - testis [nTPM]":"2.2","Tissue RNA - thalamus [nTPM]":"3.5","Tissue RNA - thymus [nTPM]":"1.8","Tissue RNA - thyroid gland [nTPM]":"3.3","Tissue RNA - tongue [nTPM]":"3.2","Tissue RNA - tonsil [nTPM]":"3.2","Tissue RNA - urinary bladder [nTPM]":"8.9","Tissue RNA - vagina [nTPM]":"3.8","Tissue RNA - white matter [nTPM]":"3.5","Cell RNA - A-431 [nTPM]":"7.0","Cell RNA - A549 [nTPM]":"5.2","Cell RNA - AF22 [nTPM]":"14.4","Cell RNA - AN3-CA [nTPM]":"33.6","Cell RNA - ASC diff [nTPM]":"36.8","Cell RNA - ASC TERT1 [nTPM]":"46.8","Cell RNA - BEWO [nTPM]":"6.5","Cell RNA - BJ [nTPM]":"34.9","Cell RNA - BJ hTERT+ [nTPM]":"32.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.3","Cell RNA - CACO-2 [nTPM]":"4.4","Cell RNA - CAPAN-2 [nTPM]":"4.3","Cell RNA - Daudi [nTPM]":"2.4","Cell RNA - EFO-21 [nTPM]":"16.0","Cell RNA - fHDF\/TERT166 [nTPM]":"31.0","Cell RNA - GAMG [nTPM]":"14.7","Cell RNA - HaCaT [nTPM]":"14.8","Cell RNA - HAP1 [nTPM]":"8.1","Cell RNA - HBEC3-KT [nTPM]":"12.8","Cell RNA - HBF TERT88 [nTPM]":"23.9","Cell RNA - HDLM-2 [nTPM]":"1.3","Cell RNA - HEK 293 [nTPM]":"11.6","Cell RNA - HEL [nTPM]":"5.6","Cell RNA - HeLa [nTPM]":"9.2","Cell RNA - Hep G2 [nTPM]":"13.1","Cell RNA - HHSteC [nTPM]":"18.6","Cell RNA - HL-60 [nTPM]":"4.0","Cell RNA - HMC-1 [nTPM]":"9.3","Cell RNA - HSkMC [nTPM]":"29.4","Cell RNA - hTCEpi [nTPM]":"13.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.9","Cell RNA - hTERT-HME1 [nTPM]":"24.6","Cell RNA - hTERT-RPE1 [nTPM]":"28.2","Cell RNA - HUVEC TERT2 [nTPM]":"27.0","Cell RNA - JURKAT [nTPM]":"3.6","Cell RNA - K-562 [nTPM]":"9.2","Cell RNA - Karpas-707 [nTPM]":"5.0","Cell RNA - LHCN-M2 [nTPM]":"21.8","Cell RNA - MCF7 [nTPM]":"2.9","Cell RNA - MOLT-4 [nTPM]":"2.1","Cell RNA - NB-4 [nTPM]":"4.9","Cell RNA - NTERA-2 [nTPM]":"7.5","Cell RNA - OE19 [nTPM]":"7.7","Cell RNA - PC-3 [nTPM]":"9.2","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"9.6","Cell RNA - RPMI-8226 [nTPM]":"8.2","Cell RNA - RPTEC TERT1 [nTPM]":"11.8","Cell RNA - RT4 [nTPM]":"6.1","Cell RNA - SCLC-21H [nTPM]":"3.8","Cell RNA - SH-SY5Y [nTPM]":"12.5","Cell RNA - SiHa [nTPM]":"12.2","Cell RNA - SK-BR-3 [nTPM]":"27.5","Cell RNA - SK-MEL-30 [nTPM]":"8.8","Cell RNA - SuSa [nTPM]":"17.0","Cell RNA - T-47d [nTPM]":"6.2","Cell RNA - THP-1 [nTPM]":"5.3","Cell RNA - TIME [nTPM]":"21.7","Cell RNA - U-138 MG [nTPM]":"12.6","Cell RNA - U-2 OS [nTPM]":"14.6","Cell RNA - U-2197 [nTPM]":"21.8","Cell RNA - U-251 MG [nTPM]":"14.0","Cell RNA - U-266\/70 [nTPM]":"7.6","Cell RNA - U-266\/84 [nTPM]":"8.3","Cell RNA - U-698 [nTPM]":"4.2","Cell RNA - U-87 MG [nTPM]":"18.0","Cell RNA - U-937 [nTPM]":"3.8","Cell RNA - WM-115 [nTPM]":"40.2","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"3.4","Brain RNA - basal ganglia [nTPM]":"3.5","Brain RNA - cerebellum [nTPM]":"5.4","Brain RNA - cerebral cortex [nTPM]":"3.6","Brain RNA - hippocampal formation [nTPM]":"3.2","Brain RNA - hypothalamus [nTPM]":"3.2","Brain RNA - medulla oblongata [nTPM]":"3.3","Brain RNA - midbrain [nTPM]":"3.1","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"3.0","Brain RNA - thalamus [nTPM]":"3.5","Brain RNA - white matter [nTPM]":"3.5","Single Cell Type RNA - Adipocytes [nTPM]":"13.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.0","Single Cell Type RNA - Astrocytes [nTPM]":"7.2","Single Cell Type RNA - B-cells [nTPM]":"7.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"27.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"35.9","Single Cell Type RNA - Bipolar cells [nTPM]":"16.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"11.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.6","Single Cell Type RNA - dendritic cells [nTPM]":"9.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"30.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"44.3","Single Cell Type RNA - Endothelial cells [nTPM]":"12.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"6.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"27.3","Single Cell Type RNA - Fibroblasts [nTPM]":"40.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"40.0","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"9.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.6","Single Cell Type RNA - Hepatocytes [nTPM]":"6.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.0","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.7","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"2.5","Single Cell Type RNA - Langerhans cells [nTPM]":"11.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.4","Single Cell Type RNA - Leydig cells [nTPM]":"13.1","Single Cell Type RNA - Macrophages [nTPM]":"5.7","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"3.6","Single Cell Type RNA - Muller glia cells [nTPM]":"26.5","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.7","Single Cell Type RNA - Paneth cells [nTPM]":"19.0","Single Cell Type RNA - Peritubular cells [nTPM]":"20.7","Single Cell Type RNA - Plasma cells [nTPM]":"43.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.4","Single Cell Type RNA - Spermatocytes [nTPM]":"1.4","Single Cell Type RNA - Spermatogonia [nTPM]":"3.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"27.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.7","Single Cell Type RNA - T-cells [nTPM]":"6.0","Single Cell Type RNA - Theca cells [nTPM]":"20.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.1","Single Cell Type RNA - Urothelial cells [nTPM]":"28.0"},{"Gene":"FLAD1","Gene synonym":["FAD1","PP591"],"Ensembl":"ENSG00000160688","Gene description":"Flavin adenine dinucleotide synthetase 1","Uniprot":["Q8NFF5"],"Chromosome":"1","Position":"154983338-154993111","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Nucleotidyltransferase","Transferase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028476","HPA028486","HPA028563"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA028476":"AB_10599974","HPA028486":"AB_10600206","HPA028563":"AB_10602286"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.04e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.55e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Tissue RNA - adipose tissue [nTPM]":"21.9","Tissue RNA - adrenal gland [nTPM]":"21.1","Tissue RNA - amygdala [nTPM]":"19.2","Tissue RNA - appendix [nTPM]":"17.0","Tissue RNA - basal ganglia [nTPM]":"20.5","Tissue RNA - bone marrow [nTPM]":"14.2","Tissue RNA - breast [nTPM]":"23.5","Tissue RNA - cerebellum [nTPM]":"20.2","Tissue RNA - cerebral cortex [nTPM]":"20.7","Tissue RNA - cervix [nTPM]":"20.4","Tissue RNA - choroid plexus [nTPM]":"19.7","Tissue RNA - colon [nTPM]":"22.8","Tissue RNA - duodenum [nTPM]":"20.1","Tissue RNA - endometrium 1 [nTPM]":"19.8","Tissue RNA - epididymis [nTPM]":"20.5","Tissue RNA - esophagus [nTPM]":"26.1","Tissue RNA - fallopian tube [nTPM]":"19.1","Tissue RNA - gallbladder [nTPM]":"11.8","Tissue RNA - heart muscle [nTPM]":"28.7","Tissue RNA - hippocampal formation [nTPM]":"20.1","Tissue RNA - hypothalamus [nTPM]":"19.5","Tissue RNA - kidney [nTPM]":"21.7","Tissue RNA - liver [nTPM]":"32.8","Tissue RNA - lung [nTPM]":"17.7","Tissue RNA - lymph node [nTPM]":"22.8","Tissue RNA - medulla oblongata [nTPM]":"20.2","Tissue RNA - midbrain [nTPM]":"20.3","Tissue RNA - ovary [nTPM]":"15.5","Tissue RNA - pancreas [nTPM]":"18.9","Tissue RNA - parathyroid gland [nTPM]":"18.0","Tissue RNA - pituitary gland [nTPM]":"15.1","Tissue RNA - placenta [nTPM]":"14.3","Tissue RNA - pons [nTPM]":"20.6","Tissue RNA - prostate [nTPM]":"24.3","Tissue RNA - rectum [nTPM]":"18.9","Tissue RNA - retina [nTPM]":"9.8","Tissue RNA - salivary gland [nTPM]":"21.0","Tissue RNA - seminal vesicle [nTPM]":"13.7","Tissue RNA - skeletal muscle [nTPM]":"34.1","Tissue RNA - skin 1 [nTPM]":"32.9","Tissue RNA - small intestine [nTPM]":"24.9","Tissue RNA - smooth muscle [nTPM]":"17.7","Tissue RNA - spinal cord [nTPM]":"19.6","Tissue RNA - spleen [nTPM]":"30.1","Tissue RNA - stomach 1 [nTPM]":"22.0","Tissue RNA - testis [nTPM]":"19.0","Tissue RNA - thalamus [nTPM]":"20.6","Tissue RNA - thymus [nTPM]":"16.0","Tissue RNA - thyroid gland [nTPM]":"22.5","Tissue RNA - tongue [nTPM]":"32.0","Tissue RNA - tonsil [nTPM]":"23.0","Tissue RNA - urinary bladder [nTPM]":"22.6","Tissue RNA - vagina [nTPM]":"21.1","Tissue RNA - white matter [nTPM]":"21.0","Cell RNA - A-431 [nTPM]":"33.4","Cell RNA - A549 [nTPM]":"52.4","Cell RNA - AF22 [nTPM]":"32.8","Cell RNA - AN3-CA [nTPM]":"56.1","Cell RNA - ASC diff [nTPM]":"27.9","Cell RNA - ASC TERT1 [nTPM]":"20.5","Cell RNA - BEWO [nTPM]":"62.1","Cell RNA - BJ [nTPM]":"24.7","Cell RNA - BJ hTERT+ [nTPM]":"20.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"35.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"30.2","Cell RNA - CACO-2 [nTPM]":"46.9","Cell RNA - CAPAN-2 [nTPM]":"40.1","Cell RNA - Daudi [nTPM]":"38.5","Cell RNA - EFO-21 [nTPM]":"48.8","Cell RNA - fHDF\/TERT166 [nTPM]":"23.0","Cell RNA - GAMG [nTPM]":"18.3","Cell RNA - HaCaT [nTPM]":"42.6","Cell RNA - HAP1 [nTPM]":"63.4","Cell RNA - HBEC3-KT [nTPM]":"51.3","Cell RNA - HBF TERT88 [nTPM]":"23.0","Cell RNA - HDLM-2 [nTPM]":"40.6","Cell RNA - HEK 293 [nTPM]":"47.5","Cell RNA - HEL [nTPM]":"31.4","Cell RNA - HeLa [nTPM]":"42.8","Cell RNA - Hep G2 [nTPM]":"33.7","Cell RNA - HHSteC [nTPM]":"38.1","Cell RNA - HL-60 [nTPM]":"46.0","Cell RNA - HMC-1 [nTPM]":"39.1","Cell RNA - HSkMC [nTPM]":"29.5","Cell RNA - hTCEpi [nTPM]":"65.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"40.2","Cell RNA - hTERT-HME1 [nTPM]":"42.8","Cell RNA - hTERT-RPE1 [nTPM]":"17.0","Cell RNA - HUVEC TERT2 [nTPM]":"41.5","Cell RNA - JURKAT [nTPM]":"40.4","Cell RNA - K-562 [nTPM]":"51.4","Cell RNA - Karpas-707 [nTPM]":"30.3","Cell RNA - LHCN-M2 [nTPM]":"30.2","Cell RNA - MCF7 [nTPM]":"71.8","Cell RNA - MOLT-4 [nTPM]":"31.9","Cell RNA - NB-4 [nTPM]":"32.0","Cell RNA - NTERA-2 [nTPM]":"71.7","Cell RNA - OE19 [nTPM]":"72.2","Cell RNA - PC-3 [nTPM]":"53.8","Cell RNA - REH [nTPM]":"52.8","Cell RNA - RH-30 [nTPM]":"16.2","Cell RNA - RPMI-8226 [nTPM]":"88.7","Cell RNA - RPTEC TERT1 [nTPM]":"33.9","Cell RNA - RT4 [nTPM]":"45.8","Cell RNA - SCLC-21H [nTPM]":"54.9","Cell RNA - SH-SY5Y [nTPM]":"75.6","Cell RNA - SiHa [nTPM]":"38.7","Cell RNA - SK-BR-3 [nTPM]":"86.2","Cell RNA - SK-MEL-30 [nTPM]":"50.0","Cell RNA - SuSa [nTPM]":"63.0","Cell RNA - T-47d [nTPM]":"74.0","Cell RNA - THP-1 [nTPM]":"68.6","Cell RNA - TIME [nTPM]":"26.4","Cell RNA - U-138 MG [nTPM]":"21.9","Cell RNA - U-2 OS [nTPM]":"30.1","Cell RNA - U-2197 [nTPM]":"28.6","Cell RNA - U-251 MG [nTPM]":"39.6","Cell RNA - U-266\/70 [nTPM]":"47.5","Cell RNA - U-266\/84 [nTPM]":"63.7","Cell RNA - U-698 [nTPM]":"66.9","Cell RNA - U-87 MG [nTPM]":"26.4","Cell RNA - U-937 [nTPM]":"36.8","Cell RNA - WM-115 [nTPM]":"36.1","Blood RNA - basophil [nTPM]":"29.8","Blood RNA - classical monocyte [nTPM]":"35.3","Blood RNA - eosinophil [nTPM]":"23.7","Blood RNA - gdT-cell [nTPM]":"34.5","Blood RNA - intermediate monocyte [nTPM]":"33.0","Blood RNA - MAIT T-cell [nTPM]":"38.9","Blood RNA - memory B-cell [nTPM]":"39.0","Blood RNA - memory CD4 T-cell [nTPM]":"31.9","Blood RNA - memory CD8 T-cell [nTPM]":"33.8","Blood RNA - myeloid DC [nTPM]":"37.7","Blood RNA - naive B-cell [nTPM]":"34.2","Blood RNA - naive CD4 T-cell [nTPM]":"29.1","Blood RNA - naive CD8 T-cell [nTPM]":"28.9","Blood RNA - neutrophil [nTPM]":"7.8","Blood RNA - NK-cell [nTPM]":"26.1","Blood RNA - non-classical monocyte [nTPM]":"41.4","Blood RNA - plasmacytoid DC [nTPM]":"38.3","Blood RNA - T-reg [nTPM]":"37.9","Blood RNA - total PBMC [nTPM]":"37.6","Brain RNA - amygdala [nTPM]":"19.2","Brain RNA - basal ganglia [nTPM]":"20.5","Brain RNA - cerebellum [nTPM]":"20.2","Brain RNA - cerebral cortex [nTPM]":"20.7","Brain RNA - hippocampal formation [nTPM]":"20.1","Brain RNA - hypothalamus [nTPM]":"19.5","Brain RNA - medulla oblongata [nTPM]":"20.2","Brain RNA - midbrain [nTPM]":"20.3","Brain RNA - pons [nTPM]":"20.6","Brain RNA - spinal cord [nTPM]":"19.6","Brain RNA - thalamus [nTPM]":"20.6","Brain RNA - white matter [nTPM]":"21.0","Single Cell Type RNA - Adipocytes [nTPM]":"12.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.6","Single Cell Type RNA - Astrocytes [nTPM]":"9.8","Single Cell Type RNA - B-cells [nTPM]":"19.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"26.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"37.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.3","Single Cell Type RNA - Bipolar cells [nTPM]":"15.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"39.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"22.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"42.5","Single Cell Type RNA - dendritic cells [nTPM]":"16.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"22.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"31.3","Single Cell Type RNA - Ductal cells [nTPM]":"24.4","Single Cell Type RNA - Early spermatids [nTPM]":"25.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.0","Single Cell Type RNA - Endothelial cells [nTPM]":"14.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.0","Single Cell Type RNA - Erythroid cells [nTPM]":"19.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"28.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"42.6","Single Cell Type RNA - Fibroblasts [nTPM]":"12.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"25.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.6","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"21.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"27.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"27.6","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.8","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"18.1","Single Cell Type RNA - Langerhans cells [nTPM]":"11.1","Single Cell Type RNA - Late spermatids [nTPM]":"77.6","Single Cell Type RNA - Leydig cells [nTPM]":"10.2","Single Cell Type RNA - Macrophages [nTPM]":"14.8","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"34.7","Single Cell Type RNA - Muller glia cells [nTPM]":"23.3","Single Cell Type RNA - NK-cells [nTPM]":"32.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"25.4","Single Cell Type RNA - Paneth cells [nTPM]":"14.9","Single Cell Type RNA - Peritubular cells [nTPM]":"9.8","Single Cell Type RNA - Plasma cells [nTPM]":"18.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"26.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"30.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"32.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.3","Single Cell Type RNA - Spermatocytes [nTPM]":"22.9","Single Cell Type RNA - Spermatogonia [nTPM]":"20.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"36.0","Single Cell Type RNA - T-cells [nTPM]":"20.2","Single Cell Type RNA - Theca cells [nTPM]":"23.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"25.4","Single Cell Type RNA - Urothelial cells [nTPM]":"20.0"},{"Gene":"FLNA","Gene synonym":["ABP-280","FLN","FLN1","OPD1","OPD2"],"Ensembl":"ENSG00000196924","Gene description":"Filamin A","Uniprot":["P21333"],"Chromosome":"X","Position":"154348524-154374634","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":["Actin-binding"],"Disease involvement":["Deafness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"endometrium 1":"1203.7","intestine":"1462.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Peritubular cells":"500.6","Sertoli cells":"420.7","Smooth muscle cells":"459.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000356","HPA000368","HPA001016","HPA001115","HPA002925"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane","Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"730000000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":["Plasma membrane","Actin filaments","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB000356":null,"HPA000368":"AB_2797215","HPA001016":null,"HPA001115":"AB_1078871","HPA002925":"AB_1078869"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.37e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.54e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.49e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.88e-4"},"Tissue RNA - adipose tissue [nTPM]":"267.4","Tissue RNA - adrenal gland [nTPM]":"55.9","Tissue RNA - amygdala [nTPM]":"14.4","Tissue RNA - appendix [nTPM]":"223.2","Tissue RNA - basal ganglia [nTPM]":"18.5","Tissue RNA - bone marrow [nTPM]":"157.9","Tissue RNA - breast [nTPM]":"164.2","Tissue RNA - cerebellum [nTPM]":"15.2","Tissue RNA - cerebral cortex [nTPM]":"43.0","Tissue RNA - cervix [nTPM]":"392.1","Tissue RNA - choroid plexus [nTPM]":"54.7","Tissue RNA - colon [nTPM]":"1462.2","Tissue RNA - duodenum [nTPM]":"89.9","Tissue RNA - endometrium 1 [nTPM]":"1203.7","Tissue RNA - epididymis [nTPM]":"35.5","Tissue RNA - esophagus [nTPM]":"454.7","Tissue RNA - fallopian tube [nTPM]":"609.4","Tissue RNA - gallbladder [nTPM]":"137.9","Tissue RNA - heart muscle [nTPM]":"108.4","Tissue RNA - hippocampal formation [nTPM]":"14.8","Tissue RNA - hypothalamus [nTPM]":"23.0","Tissue RNA - kidney [nTPM]":"70.5","Tissue RNA - liver [nTPM]":"21.2","Tissue RNA - lung [nTPM]":"238.9","Tissue RNA - lymph node [nTPM]":"65.0","Tissue RNA - medulla oblongata [nTPM]":"39.9","Tissue RNA - midbrain [nTPM]":"19.9","Tissue RNA - ovary [nTPM]":"236.7","Tissue RNA - pancreas [nTPM]":"50.5","Tissue RNA - parathyroid gland [nTPM]":"13.4","Tissue RNA - pituitary gland [nTPM]":"30.5","Tissue RNA - placenta [nTPM]":"79.2","Tissue RNA - pons [nTPM]":"24.4","Tissue RNA - prostate [nTPM]":"369.2","Tissue RNA - rectum [nTPM]":"86.9","Tissue RNA - retina [nTPM]":"9.0","Tissue RNA - salivary gland [nTPM]":"80.3","Tissue RNA - seminal vesicle [nTPM]":"617.2","Tissue RNA - skeletal muscle [nTPM]":"49.7","Tissue RNA - skin 1 [nTPM]":"124.7","Tissue RNA - small intestine [nTPM]":"354.6","Tissue RNA - smooth muscle [nTPM]":"706.6","Tissue RNA - spinal cord [nTPM]":"21.1","Tissue RNA - spleen [nTPM]":"102.7","Tissue RNA - stomach 1 [nTPM]":"508.0","Tissue RNA - testis [nTPM]":"33.7","Tissue RNA - thalamus [nTPM]":"34.0","Tissue RNA - thymus [nTPM]":"48.1","Tissue RNA - thyroid gland [nTPM]":"85.6","Tissue RNA - tongue [nTPM]":"31.2","Tissue RNA - tonsil [nTPM]":"38.1","Tissue RNA - urinary bladder [nTPM]":"1053.9","Tissue RNA - vagina [nTPM]":"286.4","Tissue RNA - white matter [nTPM]":"21.5","Cell RNA - A-431 [nTPM]":"947.2","Cell RNA - A549 [nTPM]":"719.2","Cell RNA - AF22 [nTPM]":"246.7","Cell RNA - AN3-CA [nTPM]":"316.1","Cell RNA - ASC diff [nTPM]":"209.8","Cell RNA - ASC TERT1 [nTPM]":"278.4","Cell RNA - BEWO [nTPM]":"400.9","Cell RNA - BJ [nTPM]":"614.0","Cell RNA - BJ hTERT+ [nTPM]":"680.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"552.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"489.8","Cell RNA - CACO-2 [nTPM]":"469.2","Cell RNA - CAPAN-2 [nTPM]":"169.4","Cell RNA - Daudi [nTPM]":"80.5","Cell RNA - EFO-21 [nTPM]":"1551.4","Cell RNA - fHDF\/TERT166 [nTPM]":"966.4","Cell RNA - GAMG [nTPM]":"970.1","Cell RNA - HaCaT [nTPM]":"528.3","Cell RNA - HAP1 [nTPM]":"224.0","Cell RNA - HBEC3-KT [nTPM]":"538.1","Cell RNA - HBF TERT88 [nTPM]":"152.7","Cell RNA - HDLM-2 [nTPM]":"333.6","Cell RNA - HEK 293 [nTPM]":"77.8","Cell RNA - HEL [nTPM]":"262.2","Cell RNA - HeLa [nTPM]":"914.9","Cell RNA - Hep G2 [nTPM]":"159.7","Cell RNA - HHSteC [nTPM]":"375.9","Cell RNA - HL-60 [nTPM]":"309.3","Cell RNA - HMC-1 [nTPM]":"324.9","Cell RNA - HSkMC [nTPM]":"266.1","Cell RNA - hTCEpi [nTPM]":"126.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"825.5","Cell RNA - hTERT-HME1 [nTPM]":"327.0","Cell RNA - hTERT-RPE1 [nTPM]":"533.8","Cell RNA - HUVEC TERT2 [nTPM]":"417.1","Cell RNA - JURKAT [nTPM]":"94.9","Cell RNA - K-562 [nTPM]":"74.7","Cell RNA - Karpas-707 [nTPM]":"538.7","Cell RNA - LHCN-M2 [nTPM]":"401.3","Cell RNA - MCF7 [nTPM]":"210.7","Cell RNA - MOLT-4 [nTPM]":"148.5","Cell RNA - NB-4 [nTPM]":"93.1","Cell RNA - NTERA-2 [nTPM]":"258.3","Cell RNA - OE19 [nTPM]":"97.9","Cell RNA - PC-3 [nTPM]":"470.9","Cell RNA - REH [nTPM]":"147.8","Cell RNA - RH-30 [nTPM]":"221.2","Cell RNA - RPMI-8226 [nTPM]":"71.6","Cell RNA - RPTEC TERT1 [nTPM]":"197.2","Cell RNA - RT4 [nTPM]":"193.4","Cell RNA - SCLC-21H [nTPM]":"52.9","Cell RNA - SH-SY5Y [nTPM]":"119.7","Cell RNA - SiHa [nTPM]":"515.8","Cell RNA - SK-BR-3 [nTPM]":"80.2","Cell RNA - SK-MEL-30 [nTPM]":"381.1","Cell RNA - SuSa [nTPM]":"187.3","Cell RNA - T-47d [nTPM]":"79.1","Cell RNA - THP-1 [nTPM]":"96.3","Cell RNA - TIME [nTPM]":"1016.6","Cell RNA - U-138 MG [nTPM]":"625.2","Cell RNA - U-2 OS [nTPM]":"586.8","Cell RNA - U-2197 [nTPM]":"640.0","Cell RNA - U-251 MG [nTPM]":"1147.1","Cell RNA - U-266\/70 [nTPM]":"333.7","Cell RNA - U-266\/84 [nTPM]":"212.8","Cell RNA - U-698 [nTPM]":"162.3","Cell RNA - U-87 MG [nTPM]":"580.3","Cell RNA - U-937 [nTPM]":"202.4","Cell RNA - WM-115 [nTPM]":"638.7","Blood RNA - basophil [nTPM]":"7.6","Blood RNA - classical monocyte [nTPM]":"24.9","Blood RNA - eosinophil [nTPM]":"11.8","Blood RNA - gdT-cell [nTPM]":"32.6","Blood RNA - intermediate monocyte [nTPM]":"23.1","Blood RNA - MAIT T-cell [nTPM]":"21.2","Blood RNA - memory B-cell [nTPM]":"10.2","Blood RNA - memory CD4 T-cell [nTPM]":"15.6","Blood RNA - memory CD8 T-cell [nTPM]":"29.2","Blood RNA - myeloid DC [nTPM]":"22.4","Blood RNA - naive B-cell [nTPM]":"4.6","Blood RNA - naive CD4 T-cell [nTPM]":"6.0","Blood RNA - naive CD8 T-cell [nTPM]":"14.3","Blood RNA - neutrophil [nTPM]":"3.6","Blood RNA - NK-cell [nTPM]":"10.5","Blood RNA - non-classical monocyte [nTPM]":"34.2","Blood RNA - plasmacytoid DC [nTPM]":"2.7","Blood RNA - T-reg [nTPM]":"20.7","Blood RNA - total PBMC [nTPM]":"56.2","Brain RNA - amygdala [nTPM]":"14.4","Brain RNA - basal ganglia [nTPM]":"18.5","Brain RNA - cerebellum [nTPM]":"15.2","Brain RNA - cerebral cortex [nTPM]":"43.0","Brain RNA - hippocampal formation [nTPM]":"14.8","Brain RNA - hypothalamus [nTPM]":"23.0","Brain RNA - medulla oblongata [nTPM]":"39.9","Brain RNA - midbrain [nTPM]":"19.9","Brain RNA - pons [nTPM]":"24.4","Brain RNA - spinal cord [nTPM]":"21.1","Brain RNA - thalamus [nTPM]":"34.0","Brain RNA - white matter [nTPM]":"21.5","Single Cell Type RNA - Adipocytes [nTPM]":"105.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"57.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"38.7","Single Cell Type RNA - Astrocytes [nTPM]":"30.0","Single Cell Type RNA - B-cells [nTPM]":"76.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"124.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"85.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"127.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"85.4","Single Cell Type RNA - Bipolar cells [nTPM]":"3.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"40.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"153.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"34.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"26.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"35.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"24.6","Single Cell Type RNA - dendritic cells [nTPM]":"257.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"272.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"33.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"186.3","Single Cell Type RNA - Endothelial cells [nTPM]":"107.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"39.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"133.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"90.9","Single Cell Type RNA - Fibroblasts [nTPM]":"137.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"55.8","Single Cell Type RNA - granulocytes [nTPM]":"26.0","Single Cell Type RNA - Granulosa cells [nTPM]":"334.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"81.8","Single Cell Type RNA - Hepatocytes [nTPM]":"4.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"120.3","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.5","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"141.0","Single Cell Type RNA - Langerhans cells [nTPM]":"263.0","Single Cell Type RNA - Late spermatids [nTPM]":"13.7","Single Cell Type RNA - Leydig cells [nTPM]":"122.4","Single Cell Type RNA - Macrophages [nTPM]":"227.7","Single Cell Type RNA - Melanocytes [nTPM]":"88.9","Single Cell Type RNA - Microglial cells [nTPM]":"30.9","Single Cell Type RNA - monocytes [nTPM]":"207.9","Single Cell Type RNA - Muller glia cells [nTPM]":"39.4","Single Cell Type RNA - NK-cells [nTPM]":"270.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"347.4","Single Cell Type RNA - Paneth cells [nTPM]":"1.5","Single Cell Type RNA - Peritubular cells [nTPM]":"500.6","Single Cell Type RNA - Plasma cells [nTPM]":"98.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"96.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.3","Single Cell Type RNA - Sertoli cells [nTPM]":"420.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"118.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"459.3","Single Cell Type RNA - Spermatocytes [nTPM]":"4.1","Single Cell Type RNA - Spermatogonia [nTPM]":"8.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"48.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"73.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.0","Single Cell Type RNA - T-cells [nTPM]":"172.3","Single Cell Type RNA - Theca cells [nTPM]":"134.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.3","Single Cell Type RNA - Urothelial cells [nTPM]":"35.3"},{"Gene":"FLNB","Gene synonym":["ABP-278","FH1","FLN1L","LRS1","TABP","TAP"],"Ensembl":"ENSG00000136068","Gene description":"Filamin B","Uniprot":["O75369"],"Chromosome":"3","Position":"58008400-58172251","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Differentiation","Myogenesis"],"Molecular function":["Actin-binding","Developmental protein"],"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"344.9","Pancreatic endocrine cells":"385.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"17.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"TIME":"523.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004747","HPA004886","CAB019322"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Plasma membrane","Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"20000000","Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Golgi apparatus","Actin filaments","Cytosol"],"Antibody RRID":{"CAB019322":null,"HPA004747":"AB_1848599","HPA004886":"AB_1848600"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.45e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.45e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Tissue RNA - adipose tissue [nTPM]":"74.6","Tissue RNA - adrenal gland [nTPM]":"63.1","Tissue RNA - amygdala [nTPM]":"42.8","Tissue RNA - appendix [nTPM]":"22.3","Tissue RNA - basal ganglia [nTPM]":"51.3","Tissue RNA - bone marrow [nTPM]":"7.4","Tissue RNA - breast [nTPM]":"90.4","Tissue RNA - cerebellum [nTPM]":"50.9","Tissue RNA - cerebral cortex [nTPM]":"52.4","Tissue RNA - cervix [nTPM]":"45.5","Tissue RNA - choroid plexus [nTPM]":"57.1","Tissue RNA - colon [nTPM]":"122.2","Tissue RNA - duodenum [nTPM]":"52.8","Tissue RNA - endometrium 1 [nTPM]":"75.5","Tissue RNA - epididymis [nTPM]":"120.3","Tissue RNA - esophagus [nTPM]":"57.7","Tissue RNA - fallopian tube [nTPM]":"75.9","Tissue RNA - gallbladder [nTPM]":"19.6","Tissue RNA - heart muscle [nTPM]":"47.2","Tissue RNA - hippocampal formation [nTPM]":"40.1","Tissue RNA - hypothalamus [nTPM]":"41.6","Tissue RNA - kidney [nTPM]":"96.7","Tissue RNA - liver [nTPM]":"71.5","Tissue RNA - lung [nTPM]":"49.9","Tissue RNA - lymph node [nTPM]":"24.4","Tissue RNA - medulla oblongata [nTPM]":"54.4","Tissue RNA - midbrain [nTPM]":"52.3","Tissue RNA - ovary [nTPM]":"68.9","Tissue RNA - pancreas [nTPM]":"83.2","Tissue RNA - parathyroid gland [nTPM]":"59.9","Tissue RNA - pituitary gland [nTPM]":"38.1","Tissue RNA - placenta [nTPM]":"48.0","Tissue RNA - pons [nTPM]":"52.6","Tissue RNA - prostate [nTPM]":"124.4","Tissue RNA - rectum [nTPM]":"74.4","Tissue RNA - retina [nTPM]":"10.2","Tissue RNA - salivary gland [nTPM]":"64.0","Tissue RNA - seminal vesicle [nTPM]":"51.4","Tissue RNA - skeletal muscle [nTPM]":"16.3","Tissue RNA - skin 1 [nTPM]":"91.3","Tissue RNA - small intestine [nTPM]":"92.7","Tissue RNA - smooth muscle [nTPM]":"36.2","Tissue RNA - spinal cord [nTPM]":"48.1","Tissue RNA - spleen [nTPM]":"55.3","Tissue RNA - stomach 1 [nTPM]":"70.2","Tissue RNA - testis [nTPM]":"30.4","Tissue RNA - thalamus [nTPM]":"50.0","Tissue RNA - thymus [nTPM]":"74.8","Tissue RNA - thyroid gland [nTPM]":"91.1","Tissue RNA - tongue [nTPM]":"17.8","Tissue RNA - tonsil [nTPM]":"23.8","Tissue RNA - urinary bladder [nTPM]":"114.7","Tissue RNA - vagina [nTPM]":"58.6","Tissue RNA - white matter [nTPM]":"58.3","Cell RNA - A-431 [nTPM]":"134.4","Cell RNA - A549 [nTPM]":"225.0","Cell RNA - AF22 [nTPM]":"22.3","Cell RNA - AN3-CA [nTPM]":"32.9","Cell RNA - ASC diff [nTPM]":"14.8","Cell RNA - ASC TERT1 [nTPM]":"25.0","Cell RNA - BEWO [nTPM]":"385.7","Cell RNA - BJ [nTPM]":"49.0","Cell RNA - BJ hTERT+ [nTPM]":"39.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"106.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"108.4","Cell RNA - CACO-2 [nTPM]":"227.1","Cell RNA - CAPAN-2 [nTPM]":"223.1","Cell RNA - Daudi [nTPM]":"21.9","Cell RNA - EFO-21 [nTPM]":"18.1","Cell RNA - fHDF\/TERT166 [nTPM]":"172.9","Cell RNA - GAMG [nTPM]":"172.8","Cell RNA - HaCaT [nTPM]":"215.9","Cell RNA - HAP1 [nTPM]":"42.1","Cell RNA - HBEC3-KT [nTPM]":"311.5","Cell RNA - HBF TERT88 [nTPM]":"103.0","Cell RNA - HDLM-2 [nTPM]":"121.6","Cell RNA - HEK 293 [nTPM]":"20.8","Cell RNA - HEL [nTPM]":"18.4","Cell RNA - HeLa [nTPM]":"192.7","Cell RNA - Hep G2 [nTPM]":"110.5","Cell RNA - HHSteC [nTPM]":"107.8","Cell RNA - HL-60 [nTPM]":"16.2","Cell RNA - HMC-1 [nTPM]":"63.1","Cell RNA - HSkMC [nTPM]":"40.2","Cell RNA - hTCEpi [nTPM]":"132.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"148.5","Cell RNA - hTERT-HME1 [nTPM]":"448.3","Cell RNA - hTERT-RPE1 [nTPM]":"125.2","Cell RNA - HUVEC TERT2 [nTPM]":"365.4","Cell RNA - JURKAT [nTPM]":"94.7","Cell RNA - K-562 [nTPM]":"30.9","Cell RNA - Karpas-707 [nTPM]":"6.6","Cell RNA - LHCN-M2 [nTPM]":"67.0","Cell RNA - MCF7 [nTPM]":"29.2","Cell RNA - MOLT-4 [nTPM]":"49.3","Cell RNA - NB-4 [nTPM]":"38.5","Cell RNA - NTERA-2 [nTPM]":"34.5","Cell RNA - OE19 [nTPM]":"146.6","Cell RNA - PC-3 [nTPM]":"192.1","Cell RNA - REH [nTPM]":"21.6","Cell RNA - RH-30 [nTPM]":"5.8","Cell RNA - RPMI-8226 [nTPM]":"18.7","Cell RNA - RPTEC TERT1 [nTPM]":"143.8","Cell RNA - RT4 [nTPM]":"224.6","Cell RNA - SCLC-21H [nTPM]":"24.7","Cell RNA - SH-SY5Y [nTPM]":"23.1","Cell RNA - SiHa [nTPM]":"247.3","Cell RNA - SK-BR-3 [nTPM]":"132.6","Cell RNA - SK-MEL-30 [nTPM]":"27.4","Cell RNA - SuSa [nTPM]":"160.9","Cell RNA - T-47d [nTPM]":"110.3","Cell RNA - THP-1 [nTPM]":"44.6","Cell RNA - TIME [nTPM]":"523.3","Cell RNA - U-138 MG [nTPM]":"27.8","Cell RNA - U-2 OS [nTPM]":"84.5","Cell RNA - U-2197 [nTPM]":"334.1","Cell RNA - U-251 MG [nTPM]":"175.6","Cell RNA - U-266\/70 [nTPM]":"4.8","Cell RNA - U-266\/84 [nTPM]":"1.7","Cell RNA - U-698 [nTPM]":"17.0","Cell RNA - U-87 MG [nTPM]":"102.2","Cell RNA - U-937 [nTPM]":"29.2","Cell RNA - WM-115 [nTPM]":"29.9","Blood RNA - basophil [nTPM]":"10.1","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"5.0","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"2.7","Blood RNA - memory B-cell [nTPM]":"4.1","Blood RNA - memory CD4 T-cell [nTPM]":"1.7","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"1.6","Blood RNA - naive CD4 T-cell [nTPM]":"5.1","Blood RNA - naive CD8 T-cell [nTPM]":"3.8","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"7.3","Blood RNA - non-classical monocyte [nTPM]":"1.5","Blood RNA - plasmacytoid DC [nTPM]":"17.9","Blood RNA - T-reg [nTPM]":"2.0","Blood RNA - total PBMC [nTPM]":"1.5","Brain RNA - amygdala [nTPM]":"42.8","Brain RNA - basal ganglia [nTPM]":"51.3","Brain RNA - cerebellum [nTPM]":"50.9","Brain RNA - cerebral cortex [nTPM]":"52.4","Brain RNA - hippocampal formation [nTPM]":"40.1","Brain RNA - hypothalamus [nTPM]":"41.6","Brain RNA - medulla oblongata [nTPM]":"54.4","Brain RNA - midbrain [nTPM]":"52.3","Brain RNA - pons [nTPM]":"52.6","Brain RNA - spinal cord [nTPM]":"48.1","Brain RNA - thalamus [nTPM]":"50.0","Brain RNA - white matter [nTPM]":"58.3","Single Cell Type RNA - Adipocytes [nTPM]":"133.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"30.2","Single Cell Type RNA - Astrocytes [nTPM]":"3.9","Single Cell Type RNA - B-cells [nTPM]":"11.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"50.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"42.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"73.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"29.0","Single Cell Type RNA - Bipolar cells [nTPM]":"3.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"86.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"43.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"57.2","Single Cell Type RNA - Club cells [nTPM]":"62.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"47.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"28.7","Single Cell Type RNA - dendritic cells [nTPM]":"36.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"344.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"93.8","Single Cell Type RNA - Early spermatids [nTPM]":"15.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"103.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"24.4","Single Cell Type RNA - Endothelial cells [nTPM]":"92.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"49.2","Single Cell Type RNA - Erythroid cells [nTPM]":"10.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"34.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"67.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"207.1","Single Cell Type RNA - Fibroblasts [nTPM]":"28.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"88.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"133.8","Single Cell Type RNA - granulocytes [nTPM]":"24.7","Single Cell Type RNA - Granulosa cells [nTPM]":"34.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"151.3","Single Cell Type RNA - Hepatocytes [nTPM]":"52.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.6","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"34.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"82.8","Single Cell Type RNA - Ionocytes [nTPM]":"38.7","Single Cell Type RNA - Kupffer cells [nTPM]":"11.3","Single Cell Type RNA - Langerhans cells [nTPM]":"12.2","Single Cell Type RNA - Late spermatids [nTPM]":"22.4","Single Cell Type RNA - Leydig cells [nTPM]":"16.1","Single Cell Type RNA - Macrophages [nTPM]":"11.1","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"22.5","Single Cell Type RNA - monocytes [nTPM]":"11.6","Single Cell Type RNA - Muller glia cells [nTPM]":"9.1","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"25.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"40.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"385.7","Single Cell Type RNA - Paneth cells [nTPM]":"161.0","Single Cell Type RNA - Peritubular cells [nTPM]":"27.8","Single Cell Type RNA - Plasma cells [nTPM]":"3.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"115.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"157.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"76.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"25.9","Single Cell Type RNA - Spermatocytes [nTPM]":"4.4","Single Cell Type RNA - Spermatogonia [nTPM]":"6.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"46.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"51.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"49.8","Single Cell Type RNA - T-cells [nTPM]":"9.9","Single Cell Type RNA - Theca cells [nTPM]":"84.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"93.0","Single Cell Type RNA - Urothelial cells [nTPM]":"88.4"},{"Gene":"FLNC","Gene synonym":["ABP-280","ABPL","FLN2"],"Ensembl":"ENSG00000128591","Gene description":"Filamin C","Uniprot":["Q14315"],"Chromosome":"7","Position":"128830406-128859274","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":["Actin-binding"],"Disease involvement":["Cardiomyopathy","Disease variant","Myofibrillar myopathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"635.2","skeletal muscle":"1384.8","tongue":"442.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"26","RNA single cell type specific nTPM":{"Cardiomyocytes":"1892.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ":"393.6","fHDF\/TERT166":"180.2","hTEC\/SVTERT24-B":"190.6","U-2 OS":"163.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006135","HPA071007"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"26000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA006135":"AB_1848602","HPA071007":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.80e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.17e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.69e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.73e-5"},"Tissue RNA - adipose tissue [nTPM]":"13.1","Tissue RNA - adrenal gland [nTPM]":"3.4","Tissue RNA - amygdala [nTPM]":"5.8","Tissue RNA - appendix [nTPM]":"25.9","Tissue RNA - basal ganglia [nTPM]":"11.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"5.9","Tissue RNA - cerebellum [nTPM]":"11.5","Tissue RNA - cerebral cortex [nTPM]":"9.9","Tissue RNA - cervix [nTPM]":"16.9","Tissue RNA - choroid plexus [nTPM]":"3.0","Tissue RNA - colon [nTPM]":"215.4","Tissue RNA - duodenum [nTPM]":"9.4","Tissue RNA - endometrium 1 [nTPM]":"96.6","Tissue RNA - epididymis [nTPM]":"4.6","Tissue RNA - esophagus [nTPM]":"40.3","Tissue RNA - fallopian tube [nTPM]":"35.4","Tissue RNA - gallbladder [nTPM]":"13.8","Tissue RNA - heart muscle [nTPM]":"635.2","Tissue RNA - hippocampal formation [nTPM]":"5.9","Tissue RNA - hypothalamus [nTPM]":"16.7","Tissue RNA - kidney [nTPM]":"2.8","Tissue RNA - liver [nTPM]":"1.1","Tissue RNA - lung [nTPM]":"12.5","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"52.1","Tissue RNA - midbrain [nTPM]":"11.1","Tissue RNA - ovary [nTPM]":"9.4","Tissue RNA - pancreas [nTPM]":"2.1","Tissue RNA - parathyroid gland [nTPM]":"3.2","Tissue RNA - pituitary gland [nTPM]":"1.6","Tissue RNA - placenta [nTPM]":"2.4","Tissue RNA - pons [nTPM]":"29.9","Tissue RNA - prostate [nTPM]":"71.1","Tissue RNA - rectum [nTPM]":"9.8","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"16.5","Tissue RNA - seminal vesicle [nTPM]":"100.7","Tissue RNA - skeletal muscle [nTPM]":"1384.8","Tissue RNA - skin 1 [nTPM]":"8.9","Tissue RNA - small intestine [nTPM]":"40.3","Tissue RNA - smooth muscle [nTPM]":"114.4","Tissue RNA - spinal cord [nTPM]":"51.7","Tissue RNA - spleen [nTPM]":"0.7","Tissue RNA - stomach 1 [nTPM]":"65.6","Tissue RNA - testis [nTPM]":"2.2","Tissue RNA - thalamus [nTPM]":"19.1","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"4.3","Tissue RNA - tongue [nTPM]":"442.6","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"162.7","Tissue RNA - vagina [nTPM]":"21.3","Tissue RNA - white matter [nTPM]":"49.8","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"4.2","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"34.4","Cell RNA - ASC TERT1 [nTPM]":"41.2","Cell RNA - BEWO [nTPM]":"4.1","Cell RNA - BJ [nTPM]":"393.6","Cell RNA - BJ hTERT+ [nTPM]":"73.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"109.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"52.3","Cell RNA - CACO-2 [nTPM]":"124.0","Cell RNA - CAPAN-2 [nTPM]":"1.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"64.7","Cell RNA - fHDF\/TERT166 [nTPM]":"180.2","Cell RNA - GAMG [nTPM]":"44.9","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"23.7","Cell RNA - HBEC3-KT [nTPM]":"0.9","Cell RNA - HBF TERT88 [nTPM]":"64.4","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"13.1","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"20.2","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"43.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"78.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"190.6","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"44.2","Cell RNA - HUVEC TERT2 [nTPM]":"69.0","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"49.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"75.8","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"1.5","Cell RNA - NTERA-2 [nTPM]":"64.5","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"22.6","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"127.5","Cell RNA - RPMI-8226 [nTPM]":"1.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"2.1","Cell RNA - SH-SY5Y [nTPM]":"7.0","Cell RNA - SiHa [nTPM]":"0.7","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"88.0","Cell RNA - T-47d [nTPM]":"0.4","Cell RNA - THP-1 [nTPM]":"1.6","Cell RNA - TIME [nTPM]":"144.6","Cell RNA - U-138 MG [nTPM]":"38.2","Cell RNA - U-2 OS [nTPM]":"163.5","Cell RNA - U-2197 [nTPM]":"10.1","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"129.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"5.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"5.8","Brain RNA - basal ganglia [nTPM]":"11.5","Brain RNA - cerebellum [nTPM]":"11.5","Brain RNA - cerebral cortex [nTPM]":"9.9","Brain RNA - hippocampal formation [nTPM]":"5.9","Brain RNA - hypothalamus [nTPM]":"16.7","Brain RNA - medulla oblongata [nTPM]":"52.1","Brain RNA - midbrain [nTPM]":"11.1","Brain RNA - pons [nTPM]":"29.9","Brain RNA - spinal cord [nTPM]":"51.7","Brain RNA - thalamus [nTPM]":"19.1","Brain RNA - white matter [nTPM]":"49.8","Single Cell Type RNA - Adipocytes [nTPM]":"3.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1892.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.0","Single Cell Type RNA - Endothelial cells [nTPM]":"31.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.0","Single Cell Type RNA - Fibroblasts [nTPM]":"31.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"6.9","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"5.3","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"10.5","Single Cell Type RNA - Plasma cells [nTPM]":"1.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"71.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"38.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"1.0"},{"Gene":"FLVCR1","Gene synonym":["AXPC1","FLVCR","MFSD7B","PCA","SLC49A1"],"Ensembl":"ENSG00000162769","Gene description":"FLVCR heme transporter 1","Uniprot":["Q9Y5Y0"],"Chromosome":"1","Position":"212858275-212899363","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Erythrocyte maturation","Transport"],"Molecular function":["Receptor"],"Disease involvement":["Disease variant","Neurodegeneration","Neuropathy","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"19.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"73.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"NTERA-2":"55.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046646"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA046646":"AB_2679735"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.52e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.50e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.06e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-3"},"Tissue RNA - adipose tissue [nTPM]":"2.1","Tissue RNA - adrenal gland [nTPM]":"2.4","Tissue RNA - amygdala [nTPM]":"3.4","Tissue RNA - appendix [nTPM]":"3.1","Tissue RNA - basal ganglia [nTPM]":"2.8","Tissue RNA - bone marrow [nTPM]":"6.2","Tissue RNA - breast [nTPM]":"3.1","Tissue RNA - cerebellum [nTPM]":"5.0","Tissue RNA - cerebral cortex [nTPM]":"3.7","Tissue RNA - cervix [nTPM]":"2.9","Tissue RNA - choroid plexus [nTPM]":"2.7","Tissue RNA - colon [nTPM]":"3.4","Tissue RNA - duodenum [nTPM]":"9.7","Tissue RNA - endometrium 1 [nTPM]":"2.5","Tissue RNA - epididymis [nTPM]":"4.9","Tissue RNA - esophagus [nTPM]":"2.1","Tissue RNA - fallopian tube [nTPM]":"2.4","Tissue RNA - gallbladder [nTPM]":"2.0","Tissue RNA - heart muscle [nTPM]":"1.6","Tissue RNA - hippocampal formation [nTPM]":"3.2","Tissue RNA - hypothalamus [nTPM]":"4.4","Tissue RNA - kidney [nTPM]":"2.4","Tissue RNA - liver [nTPM]":"1.8","Tissue RNA - lung [nTPM]":"2.4","Tissue RNA - lymph node [nTPM]":"2.9","Tissue RNA - medulla oblongata [nTPM]":"4.5","Tissue RNA - midbrain [nTPM]":"4.1","Tissue RNA - ovary [nTPM]":"2.4","Tissue RNA - pancreas [nTPM]":"2.6","Tissue RNA - parathyroid gland [nTPM]":"3.6","Tissue RNA - pituitary gland [nTPM]":"6.9","Tissue RNA - placenta [nTPM]":"2.4","Tissue RNA - pons [nTPM]":"5.3","Tissue RNA - prostate [nTPM]":"3.4","Tissue RNA - rectum [nTPM]":"2.8","Tissue RNA - retina [nTPM]":"7.0","Tissue RNA - salivary gland [nTPM]":"1.9","Tissue RNA - seminal vesicle [nTPM]":"1.8","Tissue RNA - skeletal muscle [nTPM]":"1.0","Tissue RNA - skin 1 [nTPM]":"2.9","Tissue RNA - small intestine [nTPM]":"19.4","Tissue RNA - smooth muscle [nTPM]":"1.7","Tissue RNA - spinal cord [nTPM]":"2.5","Tissue RNA - spleen [nTPM]":"2.6","Tissue RNA - stomach 1 [nTPM]":"4.8","Tissue RNA - testis [nTPM]":"2.8","Tissue RNA - thalamus [nTPM]":"4.3","Tissue RNA - thymus [nTPM]":"2.6","Tissue RNA - thyroid gland [nTPM]":"2.2","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"2.2","Tissue RNA - urinary bladder [nTPM]":"2.3","Tissue RNA - vagina [nTPM]":"2.3","Tissue RNA - white matter [nTPM]":"4.2","Cell RNA - A-431 [nTPM]":"8.4","Cell RNA - A549 [nTPM]":"11.0","Cell RNA - AF22 [nTPM]":"16.8","Cell RNA - AN3-CA [nTPM]":"5.1","Cell RNA - ASC diff [nTPM]":"2.8","Cell RNA - ASC TERT1 [nTPM]":"3.4","Cell RNA - BEWO [nTPM]":"31.3","Cell RNA - BJ [nTPM]":"2.4","Cell RNA - BJ hTERT+ [nTPM]":"1.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.9","Cell RNA - CACO-2 [nTPM]":"16.1","Cell RNA - CAPAN-2 [nTPM]":"15.2","Cell RNA - Daudi [nTPM]":"9.1","Cell RNA - EFO-21 [nTPM]":"4.4","Cell RNA - fHDF\/TERT166 [nTPM]":"1.7","Cell RNA - GAMG [nTPM]":"10.2","Cell RNA - HaCaT [nTPM]":"12.5","Cell RNA - HAP1 [nTPM]":"18.2","Cell RNA - HBEC3-KT [nTPM]":"5.4","Cell RNA - HBF TERT88 [nTPM]":"4.7","Cell RNA - HDLM-2 [nTPM]":"5.4","Cell RNA - HEK 293 [nTPM]":"8.0","Cell RNA - HEL [nTPM]":"5.4","Cell RNA - HeLa [nTPM]":"10.4","Cell RNA - Hep G2 [nTPM]":"14.9","Cell RNA - HHSteC [nTPM]":"3.2","Cell RNA - HL-60 [nTPM]":"14.5","Cell RNA - HMC-1 [nTPM]":"8.4","Cell RNA - HSkMC [nTPM]":"2.7","Cell RNA - hTCEpi [nTPM]":"3.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.2","Cell RNA - hTERT-HME1 [nTPM]":"6.6","Cell RNA - hTERT-RPE1 [nTPM]":"2.5","Cell RNA - HUVEC TERT2 [nTPM]":"3.8","Cell RNA - JURKAT [nTPM]":"6.4","Cell RNA - K-562 [nTPM]":"14.7","Cell RNA - Karpas-707 [nTPM]":"7.4","Cell RNA - LHCN-M2 [nTPM]":"3.2","Cell RNA - MCF7 [nTPM]":"3.2","Cell RNA - MOLT-4 [nTPM]":"4.1","Cell RNA - NB-4 [nTPM]":"7.2","Cell RNA - NTERA-2 [nTPM]":"55.3","Cell RNA - OE19 [nTPM]":"11.1","Cell RNA - PC-3 [nTPM]":"7.7","Cell RNA - REH [nTPM]":"9.0","Cell RNA - RH-30 [nTPM]":"15.4","Cell RNA - RPMI-8226 [nTPM]":"10.6","Cell RNA - RPTEC TERT1 [nTPM]":"6.0","Cell RNA - RT4 [nTPM]":"8.0","Cell RNA - SCLC-21H [nTPM]":"18.1","Cell RNA - SH-SY5Y [nTPM]":"12.7","Cell RNA - SiHa [nTPM]":"11.2","Cell RNA - SK-BR-3 [nTPM]":"11.1","Cell RNA - SK-MEL-30 [nTPM]":"10.4","Cell RNA - SuSa [nTPM]":"13.8","Cell RNA - T-47d [nTPM]":"18.2","Cell RNA - THP-1 [nTPM]":"6.7","Cell RNA - TIME [nTPM]":"2.2","Cell RNA - U-138 MG [nTPM]":"2.3","Cell RNA - U-2 OS [nTPM]":"5.6","Cell RNA - U-2197 [nTPM]":"7.7","Cell RNA - U-251 MG [nTPM]":"11.2","Cell RNA - U-266\/70 [nTPM]":"4.6","Cell RNA - U-266\/84 [nTPM]":"9.9","Cell RNA - U-698 [nTPM]":"10.8","Cell RNA - U-87 MG [nTPM]":"3.5","Cell RNA - U-937 [nTPM]":"8.3","Cell RNA - WM-115 [nTPM]":"2.9","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"1.5","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.4","Brain RNA - basal ganglia [nTPM]":"2.8","Brain RNA - cerebellum [nTPM]":"5.0","Brain RNA - cerebral cortex [nTPM]":"3.7","Brain RNA - hippocampal formation [nTPM]":"3.2","Brain RNA - hypothalamus [nTPM]":"4.4","Brain RNA - medulla oblongata [nTPM]":"4.5","Brain RNA - midbrain [nTPM]":"4.1","Brain RNA - pons [nTPM]":"5.3","Brain RNA - spinal cord [nTPM]":"2.5","Brain RNA - thalamus [nTPM]":"4.3","Brain RNA - white matter [nTPM]":"4.2","Single Cell Type RNA - Adipocytes [nTPM]":"6.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.0","Single Cell Type RNA - Astrocytes [nTPM]":"12.4","Single Cell Type RNA - B-cells [nTPM]":"8.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"24.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"12.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.9","Single Cell Type RNA - dendritic cells [nTPM]":"6.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.5","Single Cell Type RNA - Early spermatids [nTPM]":"4.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.8","Single Cell Type RNA - Endothelial cells [nTPM]":"9.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"32.4","Single Cell Type RNA - Erythroid cells [nTPM]":"9.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"28.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.7","Single Cell Type RNA - Fibroblasts [nTPM]":"8.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.6","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"20.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.0","Single Cell Type RNA - Hepatocytes [nTPM]":"9.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.5","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"39.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.6","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"10.1","Single Cell Type RNA - Langerhans cells [nTPM]":"9.6","Single Cell Type RNA - Late spermatids [nTPM]":"6.8","Single Cell Type RNA - Leydig cells [nTPM]":"6.2","Single Cell Type RNA - Macrophages [nTPM]":"9.0","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"10.5","Single Cell Type RNA - Muller glia cells [nTPM]":"5.8","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"24.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"28.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.9","Single Cell Type RNA - Paneth cells [nTPM]":"12.0","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"6.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"73.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"31.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.2","Single Cell Type RNA - Spermatocytes [nTPM]":"10.4","Single Cell Type RNA - Spermatogonia [nTPM]":"6.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - T-cells [nTPM]":"8.3","Single Cell Type RNA - Theca cells [nTPM]":"5.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.2","Single Cell Type RNA - Urothelial cells [nTPM]":"4.3"},{"Gene":"FLVCR2","Gene synonym":["C14orf58","CCT","FLJ20371","MFSD7C","SLC49A2"],"Ensembl":"ENSG00000119686","Gene description":"FLVCR heme transporter 2","Uniprot":["Q9UPI3"],"Chromosome":"14","Position":"75578620-75663214","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"75.6","Kupffer cells":"44.9","Late spermatids":"142.5","Microglial cells":"41.2","Proximal enterocytes":"50.4","Syncytiotrophoblasts":"54.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"classical monocyte":"14.0","intermediate monocyte":"14.6","myeloid DC":"7.6","non-classical monocyte":"11.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"dendritic cells":"7.6","monocytes":"14.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"53.8","ASC TERT1":"23.2","BEWO":"73.5","MCF7":"26.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037984"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 14: B-cells - Humoral immune response","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA037984":"AB_10672733"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.53e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.1","Tissue RNA - adrenal gland [nTPM]":"13.6","Tissue RNA - amygdala [nTPM]":"3.5","Tissue RNA - appendix [nTPM]":"9.3","Tissue RNA - basal ganglia [nTPM]":"3.7","Tissue RNA - bone marrow [nTPM]":"5.4","Tissue RNA - breast [nTPM]":"2.5","Tissue RNA - cerebellum [nTPM]":"3.2","Tissue RNA - cerebral cortex [nTPM]":"3.8","Tissue RNA - cervix [nTPM]":"2.1","Tissue RNA - choroid plexus [nTPM]":"16.2","Tissue RNA - colon [nTPM]":"8.4","Tissue RNA - duodenum [nTPM]":"17.4","Tissue RNA - endometrium 1 [nTPM]":"1.0","Tissue RNA - epididymis [nTPM]":"1.4","Tissue RNA - esophagus [nTPM]":"2.9","Tissue RNA - fallopian tube [nTPM]":"1.9","Tissue RNA - gallbladder [nTPM]":"3.5","Tissue RNA - heart muscle [nTPM]":"2.2","Tissue RNA - hippocampal formation [nTPM]":"2.9","Tissue RNA - hypothalamus [nTPM]":"2.7","Tissue RNA - kidney [nTPM]":"11.3","Tissue RNA - liver [nTPM]":"20.5","Tissue RNA - lung [nTPM]":"16.2","Tissue RNA - lymph node [nTPM]":"5.3","Tissue RNA - medulla oblongata [nTPM]":"4.7","Tissue RNA - midbrain [nTPM]":"3.7","Tissue RNA - ovary [nTPM]":"2.2","Tissue RNA - pancreas [nTPM]":"0.6","Tissue RNA - parathyroid gland [nTPM]":"2.1","Tissue RNA - pituitary gland [nTPM]":"3.4","Tissue RNA - placenta [nTPM]":"10.3","Tissue RNA - pons [nTPM]":"3.9","Tissue RNA - prostate [nTPM]":"2.3","Tissue RNA - rectum [nTPM]":"7.1","Tissue RNA - retina [nTPM]":"0.7","Tissue RNA - salivary gland [nTPM]":"12.7","Tissue RNA - seminal vesicle [nTPM]":"1.7","Tissue RNA - skeletal muscle [nTPM]":"8.3","Tissue RNA - skin 1 [nTPM]":"5.7","Tissue RNA - small intestine [nTPM]":"24.4","Tissue RNA - smooth muscle [nTPM]":"4.2","Tissue RNA - spinal cord [nTPM]":"5.2","Tissue RNA - spleen [nTPM]":"13.8","Tissue RNA - stomach 1 [nTPM]":"0.9","Tissue RNA - testis [nTPM]":"21.1","Tissue RNA - thalamus [nTPM]":"4.8","Tissue RNA - thymus [nTPM]":"1.2","Tissue RNA - thyroid gland [nTPM]":"3.2","Tissue RNA - tongue [nTPM]":"1.6","Tissue RNA - tonsil [nTPM]":"5.0","Tissue RNA - urinary bladder [nTPM]":"4.9","Tissue RNA - vagina [nTPM]":"2.6","Tissue RNA - white matter [nTPM]":"5.5","Cell RNA - A-431 [nTPM]":"3.7","Cell RNA - A549 [nTPM]":"2.8","Cell RNA - AF22 [nTPM]":"0.8","Cell RNA - AN3-CA [nTPM]":"4.0","Cell RNA - ASC diff [nTPM]":"53.8","Cell RNA - ASC TERT1 [nTPM]":"23.2","Cell RNA - BEWO [nTPM]":"73.5","Cell RNA - BJ [nTPM]":"0.7","Cell RNA - BJ hTERT+ [nTPM]":"3.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.6","Cell RNA - CACO-2 [nTPM]":"6.2","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"5.4","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"9.8","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"1.3","Cell RNA - HDLM-2 [nTPM]":"19.3","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"2.8","Cell RNA - Hep G2 [nTPM]":"13.3","Cell RNA - HHSteC [nTPM]":"4.3","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"10.9","Cell RNA - hTCEpi [nTPM]":"7.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.0","Cell RNA - hTERT-HME1 [nTPM]":"2.4","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.8","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"10.1","Cell RNA - MCF7 [nTPM]":"26.4","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"1.9","Cell RNA - NTERA-2 [nTPM]":"1.6","Cell RNA - OE19 [nTPM]":"1.1","Cell RNA - PC-3 [nTPM]":"4.4","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"2.6","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"3.5","Cell RNA - RT4 [nTPM]":"5.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"2.0","Cell RNA - SK-BR-3 [nTPM]":"8.1","Cell RNA - SK-MEL-30 [nTPM]":"1.6","Cell RNA - SuSa [nTPM]":"4.6","Cell RNA - T-47d [nTPM]":"4.5","Cell RNA - THP-1 [nTPM]":"10.1","Cell RNA - TIME [nTPM]":"8.8","Cell RNA - U-138 MG [nTPM]":"4.0","Cell RNA - U-2 OS [nTPM]":"1.4","Cell RNA - U-2197 [nTPM]":"2.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.6","Cell RNA - U-266\/84 [nTPM]":"1.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"11.4","Cell RNA - U-937 [nTPM]":"2.5","Cell RNA - WM-115 [nTPM]":"0.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"14.0","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"14.6","Blood RNA - MAIT T-cell [nTPM]":"1.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"7.6","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"11.8","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"1.6","Blood RNA - total PBMC [nTPM]":"4.1","Brain RNA - amygdala [nTPM]":"3.5","Brain RNA - basal ganglia [nTPM]":"3.7","Brain RNA - cerebellum [nTPM]":"3.2","Brain RNA - cerebral cortex [nTPM]":"3.8","Brain RNA - hippocampal formation [nTPM]":"2.9","Brain RNA - hypothalamus [nTPM]":"2.7","Brain RNA - medulla oblongata [nTPM]":"4.7","Brain RNA - midbrain [nTPM]":"3.7","Brain RNA - pons [nTPM]":"3.9","Brain RNA - spinal cord [nTPM]":"5.2","Brain RNA - thalamus [nTPM]":"4.8","Brain RNA - white matter [nTPM]":"5.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.4","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.2","Single Cell Type RNA - dendritic cells [nTPM]":"1.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"75.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.9","Single Cell Type RNA - Endothelial cells [nTPM]":"2.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"31.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.7","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"21.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.2","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"44.9","Single Cell Type RNA - Langerhans cells [nTPM]":"5.6","Single Cell Type RNA - Late spermatids [nTPM]":"142.5","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"19.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"41.2","Single Cell Type RNA - monocytes [nTPM]":"10.1","Single Cell Type RNA - Muller glia cells [nTPM]":"1.3","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"3.2","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"50.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"2.4","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"54.5","Single Cell Type RNA - T-cells [nTPM]":"1.2","Single Cell Type RNA - Theca cells [nTPM]":"2.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"FMO3","Gene synonym":["FMOII"],"Ensembl":"ENSG00000007933","Gene description":"Flavin containing dimethylaniline monoxygenase 3","Uniprot":["P31513"],"Chromosome":"1","Position":"171090901-171117819","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"41","RNA tissue specific nTPM":{"liver":"1123.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Hepatocytes":"412.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"13","RNA cancer specific FPKM":{"liver cancer":"94.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"ASC diff":"34.6","ASC TERT1":"26.0"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013750"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA013750":"AB_1848968"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.46e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.60e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.13e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.27e-2"},"Tissue RNA - adipose tissue [nTPM]":"27.2","Tissue RNA - adrenal gland [nTPM]":"12.4","Tissue RNA - amygdala [nTPM]":"2.5","Tissue RNA - appendix [nTPM]":"0.9","Tissue RNA - basal ganglia [nTPM]":"2.7","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"6.8","Tissue RNA - cerebellum [nTPM]":"2.5","Tissue RNA - cerebral cortex [nTPM]":"3.6","Tissue RNA - cervix [nTPM]":"1.2","Tissue RNA - choroid plexus [nTPM]":"2.3","Tissue RNA - colon [nTPM]":"1.4","Tissue RNA - duodenum [nTPM]":"1.8","Tissue RNA - endometrium 1 [nTPM]":"1.3","Tissue RNA - epididymis [nTPM]":"3.0","Tissue RNA - esophagus [nTPM]":"5.1","Tissue RNA - fallopian tube [nTPM]":"13.3","Tissue RNA - gallbladder [nTPM]":"1.8","Tissue RNA - heart muscle [nTPM]":"4.2","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"2.6","Tissue RNA - kidney [nTPM]":"14.0","Tissue RNA - liver [nTPM]":"1123.3","Tissue RNA - lung [nTPM]":"18.7","Tissue RNA - lymph node [nTPM]":"4.9","Tissue RNA - medulla oblongata [nTPM]":"5.0","Tissue RNA - midbrain [nTPM]":"2.7","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"4.5","Tissue RNA - parathyroid gland [nTPM]":"4.2","Tissue RNA - pituitary gland [nTPM]":"4.3","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"3.1","Tissue RNA - prostate [nTPM]":"1.1","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"5.1","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"4.6","Tissue RNA - skin 1 [nTPM]":"4.3","Tissue RNA - small intestine [nTPM]":"2.2","Tissue RNA - smooth muscle [nTPM]":"1.6","Tissue RNA - spinal cord [nTPM]":"4.0","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"3.9","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"2.8","Tissue RNA - thymus [nTPM]":"1.4","Tissue RNA - thyroid gland [nTPM]":"2.6","Tissue RNA - tongue [nTPM]":"3.1","Tissue RNA - tonsil [nTPM]":"9.1","Tissue RNA - urinary bladder [nTPM]":"1.0","Tissue RNA - vagina [nTPM]":"0.9","Tissue RNA - white matter [nTPM]":"2.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"34.6","Cell RNA - ASC TERT1 [nTPM]":"26.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"1.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"1.3","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"7.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"1.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.5","Brain RNA - basal ganglia [nTPM]":"2.7","Brain RNA - cerebellum [nTPM]":"2.5","Brain RNA - cerebral cortex [nTPM]":"3.6","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"2.6","Brain RNA - medulla oblongata [nTPM]":"5.0","Brain RNA - midbrain [nTPM]":"2.7","Brain RNA - pons [nTPM]":"3.1","Brain RNA - spinal cord [nTPM]":"4.0","Brain RNA - thalamus [nTPM]":"2.8","Brain RNA - white matter [nTPM]":"2.6","Single Cell Type RNA - Adipocytes [nTPM]":"2.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"17.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"4.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"29.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"12.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"412.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"9.5","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"FOLR1","Gene synonym":["FOLR","FR\u00c3\u017d\u00c2\u00b1"],"Ensembl":"ENSG00000110195","Gene description":"Folate receptor alpha","Uniprot":["P15328"],"Chromosome":"11","Position":"72189558-72196323","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Receptor"],"Disease involvement":["Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"480.2","fallopian tube":"187.2","lung":"193.5","salivary gland":"219.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"496.8","Alveolar cells type 2":"213.3","Breast glandular cells":"211.3","Club cells":"276.3","Collecting duct cells":"318.2","Cytotrophoblasts":"462.2","Proximal tubular cells":"366.0","Syncytiotrophoblasts":"259.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"259.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"HeLa":"444.2","RPTEC TERT1":"476.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077030"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":448000,"Blood concentration - Conc. blood MS [pg\/L]":"140000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 30: Mammary glandular cells - Lactation","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA077030":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.50e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"1.7","Tissue RNA - amygdala [nTPM]":"2.7","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"1.8","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"28.3","Tissue RNA - cerebellum [nTPM]":"11.8","Tissue RNA - cerebral cortex [nTPM]":"1.8","Tissue RNA - cervix [nTPM]":"123.5","Tissue RNA - choroid plexus [nTPM]":"480.2","Tissue RNA - colon [nTPM]":"0.5","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"1.9","Tissue RNA - epididymis [nTPM]":"7.6","Tissue RNA - esophagus [nTPM]":"3.4","Tissue RNA - fallopian tube [nTPM]":"187.2","Tissue RNA - gallbladder [nTPM]":"2.4","Tissue RNA - heart muscle [nTPM]":"0.6","Tissue RNA - hippocampal formation [nTPM]":"14.1","Tissue RNA - hypothalamus [nTPM]":"4.1","Tissue RNA - kidney [nTPM]":"153.0","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"193.5","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"5.7","Tissue RNA - midbrain [nTPM]":"7.8","Tissue RNA - ovary [nTPM]":"0.7","Tissue RNA - pancreas [nTPM]":"7.1","Tissue RNA - parathyroid gland [nTPM]":"17.5","Tissue RNA - pituitary gland [nTPM]":"8.1","Tissue RNA - placenta [nTPM]":"36.2","Tissue RNA - pons [nTPM]":"3.8","Tissue RNA - prostate [nTPM]":"1.5","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"219.5","Tissue RNA - seminal vesicle [nTPM]":"15.2","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"2.5","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"3.2","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"33.0","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"7.7","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"45.9","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"2.7","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"64.7","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"44.5","Cell RNA - CAPAN-2 [nTPM]":"46.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"45.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.8","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.9","Cell RNA - HAP1 [nTPM]":"2.4","Cell RNA - HBEC3-KT [nTPM]":"2.1","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"1.4","Cell RNA - HEL [nTPM]":"1.0","Cell RNA - HeLa [nTPM]":"444.2","Cell RNA - Hep G2 [nTPM]":"1.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"1.8","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.5","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.3","Cell RNA - MCF7 [nTPM]":"0.5","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"2.2","Cell RNA - OE19 [nTPM]":"0.7","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.5","Cell RNA - RH-30 [nTPM]":"15.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"476.5","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"3.0","Cell RNA - SiHa [nTPM]":"1.4","Cell RNA - SK-BR-3 [nTPM]":"7.1","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"38.5","Cell RNA - T-47d [nTPM]":"65.7","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"8.4","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.6","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.7","Brain RNA - basal ganglia [nTPM]":"1.8","Brain RNA - cerebellum [nTPM]":"11.8","Brain RNA - cerebral cortex [nTPM]":"1.8","Brain RNA - hippocampal formation [nTPM]":"14.1","Brain RNA - hypothalamus [nTPM]":"4.1","Brain RNA - medulla oblongata [nTPM]":"5.7","Brain RNA - midbrain [nTPM]":"7.8","Brain RNA - pons [nTPM]":"3.8","Brain RNA - spinal cord [nTPM]":"3.2","Brain RNA - thalamus [nTPM]":"7.7","Brain RNA - white matter [nTPM]":"2.7","Single Cell Type RNA - Adipocytes [nTPM]":"1.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"496.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"213.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"80.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"211.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"62.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"34.3","Single Cell Type RNA - Club cells [nTPM]":"276.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"318.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"462.2","Single Cell Type RNA - dendritic cells [nTPM]":"1.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"133.1","Single Cell Type RNA - Ductal cells [nTPM]":"14.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"33.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.3","Single Cell Type RNA - Endothelial cells [nTPM]":"3.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"110.9","Single Cell Type RNA - Fibroblasts [nTPM]":"4.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"33.7","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"29.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"87.5","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"3.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"366.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"149.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"259.0","Single Cell Type RNA - T-cells [nTPM]":"2.2","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"10.4"},{"Gene":"FRMD7","Gene synonym":["FLJ43346","NYS","NYS1"],"Ensembl":"ENSG00000165694","Gene description":"FERM domain containing 7","Uniprot":["Q6ZUT3"],"Chromosome":"X","Position":"132076990-132128020","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Neurogenesis"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"endometrium 1":"2.9","kidney":"2.7","smooth muscle":"2.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"19","RNA single cell type specific nTPM":{"Distal tubular cells":"9.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-87 MG":"1.5"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"28","RNA mouse brain regional specific nTPM":{"olfactory bulb":"65.7"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"86","RNA pig brain regional specific nTPM":{"olfactory bulb":"21.3"},"Antibody":["HPA000886"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA000886":"AB_1079269"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"2.9","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"2.7","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.5","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"2.2","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.4","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.9","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.5","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"FTCD","Gene synonym":[],"Ensembl":"ENSG00000160282","Gene description":"Formimidoyltransferase cyclodeaminase","Uniprot":["O95954"],"Chromosome":"21","Position":"46136262-46155579","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Histidine metabolism"],"Molecular function":["Lyase","Multifunctional enzyme","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"liver":"939.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"131.5","Early spermatids":"104.7","Hepatocytes":"444.9","Late spermatids":"124.3","Proximal tubular cells":"395.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"liver cancer":"87.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"30","RNA cell line specific nTPM":{"Hep G2":"92.9"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020073","HPA030928","HPA030929","HPA036114"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1600000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA020073":"AB_1849005","HPA030928":"AB_2673664","HPA030929":"AB_2673665","HPA036114":"AB_2674947"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.70e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.78e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.78e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"1.7","Tissue RNA - amygdala [nTPM]":"5.4","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"6.8","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"3.6","Tissue RNA - cerebral cortex [nTPM]":"8.4","Tissue RNA - cervix [nTPM]":"1.3","Tissue RNA - choroid plexus [nTPM]":"3.0","Tissue RNA - colon [nTPM]":"1.3","Tissue RNA - duodenum [nTPM]":"1.3","Tissue RNA - endometrium 1 [nTPM]":"1.2","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"1.6","Tissue RNA - hippocampal formation [nTPM]":"4.9","Tissue RNA - hypothalamus [nTPM]":"4.7","Tissue RNA - kidney [nTPM]":"155.7","Tissue RNA - liver [nTPM]":"939.8","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"4.6","Tissue RNA - midbrain [nTPM]":"3.9","Tissue RNA - ovary [nTPM]":"3.0","Tissue RNA - pancreas [nTPM]":"4.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"3.4","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"5.6","Tissue RNA - prostate [nTPM]":"4.2","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"1.7","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"3.5","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"13.9","Tissue RNA - thalamus [nTPM]":"4.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.9","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"1.3","Tissue RNA - vagina [nTPM]":"1.0","Tissue RNA - white matter [nTPM]":"5.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.4","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"3.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.7","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"92.9","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.6","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.7","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.9","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.9","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"5.4","Brain RNA - basal ganglia [nTPM]":"6.8","Brain RNA - cerebellum [nTPM]":"3.6","Brain RNA - cerebral cortex [nTPM]":"8.4","Brain RNA - hippocampal formation [nTPM]":"4.9","Brain RNA - hypothalamus [nTPM]":"4.7","Brain RNA - medulla oblongata [nTPM]":"4.6","Brain RNA - midbrain [nTPM]":"3.9","Brain RNA - pons [nTPM]":"5.6","Brain RNA - spinal cord [nTPM]":"3.5","Brain RNA - thalamus [nTPM]":"4.4","Brain RNA - white matter [nTPM]":"5.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"8.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"131.5","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"46.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"104.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"61.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"30.4","Single Cell Type RNA - Hepatocytes [nTPM]":"444.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"28.9","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"124.3","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"1.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"395.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"39.2","Single Cell Type RNA - Spermatogonia [nTPM]":"17.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"3.6","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"FTO","Gene synonym":["ALKBH9","KIAA1752","MGC5149"],"Ensembl":"ENSG00000140718","Gene description":"FTO alpha-ketoglutarate dependent dioxygenase","Uniprot":["Q9C0B1"],"Chromosome":"16","Position":"53701692-54158512","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Dioxygenase","Oxidoreductase","Transferase"],"Disease involvement":["Disease variant","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"173.3","Excitatory neurons":"226.1","Inhibitory neurons":"240.7","Oligodendrocyte precursor cells":"210.6","Oligodendrocytes":"282.5","Respiratory ciliated cells":"182.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017123","HPA041086","HPA068695"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"540000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB017123":null,"HPA041086":"AB_2677293","HPA068695":"AB_2732117"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-3"},"Tissue RNA - adipose tissue [nTPM]":"24.4","Tissue RNA - adrenal gland [nTPM]":"33.6","Tissue RNA - amygdala [nTPM]":"31.8","Tissue RNA - appendix [nTPM]":"12.5","Tissue RNA - basal ganglia [nTPM]":"36.6","Tissue RNA - bone marrow [nTPM]":"8.2","Tissue RNA - breast [nTPM]":"36.3","Tissue RNA - cerebellum [nTPM]":"30.1","Tissue RNA - cerebral cortex [nTPM]":"37.7","Tissue RNA - cervix [nTPM]":"25.8","Tissue RNA - choroid plexus [nTPM]":"31.0","Tissue RNA - colon [nTPM]":"22.2","Tissue RNA - duodenum [nTPM]":"7.7","Tissue RNA - endometrium 1 [nTPM]":"26.9","Tissue RNA - epididymis [nTPM]":"21.4","Tissue RNA - esophagus [nTPM]":"17.2","Tissue RNA - fallopian tube [nTPM]":"25.3","Tissue RNA - gallbladder [nTPM]":"21.6","Tissue RNA - heart muscle [nTPM]":"27.1","Tissue RNA - hippocampal formation [nTPM]":"35.2","Tissue RNA - hypothalamus [nTPM]":"39.5","Tissue RNA - kidney [nTPM]":"25.0","Tissue RNA - liver [nTPM]":"17.4","Tissue RNA - lung [nTPM]":"36.8","Tissue RNA - lymph node [nTPM]":"15.0","Tissue RNA - medulla oblongata [nTPM]":"29.2","Tissue RNA - midbrain [nTPM]":"31.3","Tissue RNA - ovary [nTPM]":"27.2","Tissue RNA - pancreas [nTPM]":"20.7","Tissue RNA - parathyroid gland [nTPM]":"40.6","Tissue RNA - pituitary gland [nTPM]":"26.2","Tissue RNA - placenta [nTPM]":"20.1","Tissue RNA - pons [nTPM]":"31.9","Tissue RNA - prostate [nTPM]":"20.0","Tissue RNA - rectum [nTPM]":"14.1","Tissue RNA - retina [nTPM]":"38.4","Tissue RNA - salivary gland [nTPM]":"18.9","Tissue RNA - seminal vesicle [nTPM]":"23.9","Tissue RNA - skeletal muscle [nTPM]":"33.1","Tissue RNA - skin 1 [nTPM]":"21.4","Tissue RNA - small intestine [nTPM]":"12.5","Tissue RNA - smooth muscle [nTPM]":"29.9","Tissue RNA - spinal cord [nTPM]":"30.5","Tissue RNA - spleen [nTPM]":"16.4","Tissue RNA - stomach 1 [nTPM]":"15.0","Tissue RNA - testis [nTPM]":"8.3","Tissue RNA - thalamus [nTPM]":"33.8","Tissue RNA - thymus [nTPM]":"17.0","Tissue RNA - thyroid gland [nTPM]":"27.5","Tissue RNA - tongue [nTPM]":"23.0","Tissue RNA - tonsil [nTPM]":"14.8","Tissue RNA - urinary bladder [nTPM]":"21.9","Tissue RNA - vagina [nTPM]":"18.5","Tissue RNA - white matter [nTPM]":"43.9","Cell RNA - A-431 [nTPM]":"15.1","Cell RNA - A549 [nTPM]":"26.8","Cell RNA - AF22 [nTPM]":"35.0","Cell RNA - AN3-CA [nTPM]":"35.9","Cell RNA - ASC diff [nTPM]":"67.3","Cell RNA - ASC TERT1 [nTPM]":"50.4","Cell RNA - BEWO [nTPM]":"11.5","Cell RNA - BJ [nTPM]":"35.6","Cell RNA - BJ hTERT+ [nTPM]":"32.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"29.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.5","Cell RNA - CACO-2 [nTPM]":"16.8","Cell RNA - CAPAN-2 [nTPM]":"19.3","Cell RNA - Daudi [nTPM]":"34.4","Cell RNA - EFO-21 [nTPM]":"38.2","Cell RNA - fHDF\/TERT166 [nTPM]":"46.3","Cell RNA - GAMG [nTPM]":"16.6","Cell RNA - HaCaT [nTPM]":"21.7","Cell RNA - HAP1 [nTPM]":"32.4","Cell RNA - HBEC3-KT [nTPM]":"34.9","Cell RNA - HBF TERT88 [nTPM]":"42.5","Cell RNA - HDLM-2 [nTPM]":"16.0","Cell RNA - HEK 293 [nTPM]":"25.5","Cell RNA - HEL [nTPM]":"15.5","Cell RNA - HeLa [nTPM]":"33.6","Cell RNA - Hep G2 [nTPM]":"31.7","Cell RNA - HHSteC [nTPM]":"46.2","Cell RNA - HL-60 [nTPM]":"12.5","Cell RNA - HMC-1 [nTPM]":"17.1","Cell RNA - HSkMC [nTPM]":"55.9","Cell RNA - hTCEpi [nTPM]":"36.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.6","Cell RNA - hTERT-HME1 [nTPM]":"32.5","Cell RNA - hTERT-RPE1 [nTPM]":"36.6","Cell RNA - HUVEC TERT2 [nTPM]":"44.1","Cell RNA - JURKAT [nTPM]":"25.1","Cell RNA - K-562 [nTPM]":"15.2","Cell RNA - Karpas-707 [nTPM]":"8.4","Cell RNA - LHCN-M2 [nTPM]":"48.1","Cell RNA - MCF7 [nTPM]":"11.8","Cell RNA - MOLT-4 [nTPM]":"28.0","Cell RNA - NB-4 [nTPM]":"19.2","Cell RNA - NTERA-2 [nTPM]":"18.1","Cell RNA - OE19 [nTPM]":"15.5","Cell RNA - PC-3 [nTPM]":"17.5","Cell RNA - REH [nTPM]":"42.2","Cell RNA - RH-30 [nTPM]":"52.9","Cell RNA - RPMI-8226 [nTPM]":"32.3","Cell RNA - RPTEC TERT1 [nTPM]":"44.6","Cell RNA - RT4 [nTPM]":"12.3","Cell RNA - SCLC-21H [nTPM]":"43.0","Cell RNA - SH-SY5Y [nTPM]":"29.7","Cell RNA - SiHa [nTPM]":"40.4","Cell RNA - SK-BR-3 [nTPM]":"23.6","Cell RNA - SK-MEL-30 [nTPM]":"10.8","Cell RNA - SuSa [nTPM]":"33.7","Cell RNA - T-47d [nTPM]":"31.1","Cell RNA - THP-1 [nTPM]":"29.3","Cell RNA - TIME [nTPM]":"42.4","Cell RNA - U-138 MG [nTPM]":"36.4","Cell RNA - U-2 OS [nTPM]":"23.9","Cell RNA - U-2197 [nTPM]":"19.8","Cell RNA - U-251 MG [nTPM]":"22.1","Cell RNA - U-266\/70 [nTPM]":"15.9","Cell RNA - U-266\/84 [nTPM]":"13.9","Cell RNA - U-698 [nTPM]":"35.0","Cell RNA - U-87 MG [nTPM]":"33.9","Cell RNA - U-937 [nTPM]":"22.9","Cell RNA - WM-115 [nTPM]":"28.7","Blood RNA - basophil [nTPM]":"14.9","Blood RNA - classical monocyte [nTPM]":"17.9","Blood RNA - eosinophil [nTPM]":"9.7","Blood RNA - gdT-cell [nTPM]":"25.6","Blood RNA - intermediate monocyte [nTPM]":"22.7","Blood RNA - MAIT T-cell [nTPM]":"32.4","Blood RNA - memory B-cell [nTPM]":"17.6","Blood RNA - memory CD4 T-cell [nTPM]":"24.4","Blood RNA - memory CD8 T-cell [nTPM]":"25.9","Blood RNA - myeloid DC [nTPM]":"23.8","Blood RNA - naive B-cell [nTPM]":"17.4","Blood RNA - naive CD4 T-cell [nTPM]":"22.5","Blood RNA - naive CD8 T-cell [nTPM]":"24.4","Blood RNA - neutrophil [nTPM]":"2.9","Blood RNA - NK-cell [nTPM]":"26.4","Blood RNA - non-classical monocyte [nTPM]":"16.5","Blood RNA - plasmacytoid DC [nTPM]":"9.5","Blood RNA - T-reg [nTPM]":"26.6","Blood RNA - total PBMC [nTPM]":"23.1","Brain RNA - amygdala [nTPM]":"31.8","Brain RNA - basal ganglia [nTPM]":"36.6","Brain RNA - cerebellum [nTPM]":"30.1","Brain RNA - cerebral cortex [nTPM]":"37.7","Brain RNA - hippocampal formation [nTPM]":"35.2","Brain RNA - hypothalamus [nTPM]":"39.5","Brain RNA - medulla oblongata [nTPM]":"29.2","Brain RNA - midbrain [nTPM]":"31.3","Brain RNA - pons [nTPM]":"31.9","Brain RNA - spinal cord [nTPM]":"30.5","Brain RNA - thalamus [nTPM]":"33.8","Brain RNA - white matter [nTPM]":"43.9","Single Cell Type RNA - Adipocytes [nTPM]":"15.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"80.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"62.0","Single Cell Type RNA - Astrocytes [nTPM]":"173.3","Single Cell Type RNA - B-cells [nTPM]":"10.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"22.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"69.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"39.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"22.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"54.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.3","Single Cell Type RNA - dendritic cells [nTPM]":"10.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.0","Single Cell Type RNA - Early spermatids [nTPM]":"39.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.3","Single Cell Type RNA - Endothelial cells [nTPM]":"17.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.6","Single Cell Type RNA - Erythroid cells [nTPM]":"9.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"226.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.4","Single Cell Type RNA - Fibroblasts [nTPM]":"23.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.9","Single Cell Type RNA - granulocytes [nTPM]":"25.9","Single Cell Type RNA - Granulosa cells [nTPM]":"16.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"13.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.2","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"240.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.6","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"9.0","Single Cell Type RNA - Langerhans cells [nTPM]":"13.2","Single Cell Type RNA - Late spermatids [nTPM]":"69.9","Single Cell Type RNA - Leydig cells [nTPM]":"14.3","Single Cell Type RNA - Macrophages [nTPM]":"11.8","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"134.0","Single Cell Type RNA - monocytes [nTPM]":"5.5","Single Cell Type RNA - Muller glia cells [nTPM]":"19.6","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"210.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"282.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.5","Single Cell Type RNA - Paneth cells [nTPM]":"5.0","Single Cell Type RNA - Peritubular cells [nTPM]":"15.1","Single Cell Type RNA - Plasma cells [nTPM]":"18.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"182.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.8","Single Cell Type RNA - Spermatocytes [nTPM]":"3.5","Single Cell Type RNA - Spermatogonia [nTPM]":"3.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.1","Single Cell Type RNA - T-cells [nTPM]":"12.9","Single Cell Type RNA - Theca cells [nTPM]":"17.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.3","Single Cell Type RNA - Urothelial cells [nTPM]":"7.9"},{"Gene":"FTSJ1","Gene synonym":["CDLIV","JM23","MRX44","MRX9","SPB1","TRM7","TRMT7"],"Ensembl":"ENSG00000068438","Gene description":"FtsJ RNA 2'-O-methyltransferase 1","Uniprot":["Q9UET6"],"Chromosome":"X","Position":"48476021-48486364","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["tRNA processing"],"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":["Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"75.7","Pancreatic endocrine cells":"60.1","Plasma cells":"59.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002718"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA002718":"AB_1078914"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.74e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.24e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Tissue RNA - adipose tissue [nTPM]":"14.6","Tissue RNA - adrenal gland [nTPM]":"15.2","Tissue RNA - amygdala [nTPM]":"5.7","Tissue RNA - appendix [nTPM]":"14.5","Tissue RNA - basal ganglia [nTPM]":"6.8","Tissue RNA - bone marrow [nTPM]":"16.0","Tissue RNA - breast [nTPM]":"13.8","Tissue RNA - cerebellum [nTPM]":"6.5","Tissue RNA - cerebral cortex [nTPM]":"9.0","Tissue RNA - cervix [nTPM]":"16.0","Tissue RNA - choroid plexus [nTPM]":"5.2","Tissue RNA - colon [nTPM]":"10.2","Tissue RNA - duodenum [nTPM]":"8.2","Tissue RNA - endometrium 1 [nTPM]":"13.8","Tissue RNA - epididymis [nTPM]":"4.6","Tissue RNA - esophagus [nTPM]":"14.9","Tissue RNA - fallopian tube [nTPM]":"12.1","Tissue RNA - gallbladder [nTPM]":"8.6","Tissue RNA - heart muscle [nTPM]":"11.4","Tissue RNA - hippocampal formation [nTPM]":"6.6","Tissue RNA - hypothalamus [nTPM]":"6.7","Tissue RNA - kidney [nTPM]":"10.1","Tissue RNA - liver [nTPM]":"9.8","Tissue RNA - lung [nTPM]":"13.3","Tissue RNA - lymph node [nTPM]":"16.2","Tissue RNA - medulla oblongata [nTPM]":"6.0","Tissue RNA - midbrain [nTPM]":"6.2","Tissue RNA - ovary [nTPM]":"12.7","Tissue RNA - pancreas [nTPM]":"16.8","Tissue RNA - parathyroid gland [nTPM]":"12.4","Tissue RNA - pituitary gland [nTPM]":"12.2","Tissue RNA - placenta [nTPM]":"8.4","Tissue RNA - pons [nTPM]":"6.2","Tissue RNA - prostate [nTPM]":"10.3","Tissue RNA - rectum [nTPM]":"7.7","Tissue RNA - retina [nTPM]":"5.7","Tissue RNA - salivary gland [nTPM]":"15.4","Tissue RNA - seminal vesicle [nTPM]":"12.8","Tissue RNA - skeletal muscle [nTPM]":"14.8","Tissue RNA - skin 1 [nTPM]":"14.2","Tissue RNA - small intestine [nTPM]":"10.2","Tissue RNA - smooth muscle [nTPM]":"12.3","Tissue RNA - spinal cord [nTPM]":"6.2","Tissue RNA - spleen [nTPM]":"13.7","Tissue RNA - stomach 1 [nTPM]":"13.7","Tissue RNA - testis [nTPM]":"9.8","Tissue RNA - thalamus [nTPM]":"5.8","Tissue RNA - thymus [nTPM]":"14.8","Tissue RNA - thyroid gland [nTPM]":"14.3","Tissue RNA - tongue [nTPM]":"10.9","Tissue RNA - tonsil [nTPM]":"13.4","Tissue RNA - urinary bladder [nTPM]":"14.3","Tissue RNA - vagina [nTPM]":"14.1","Tissue RNA - white matter [nTPM]":"6.6","Cell RNA - A-431 [nTPM]":"75.9","Cell RNA - A549 [nTPM]":"51.1","Cell RNA - AF22 [nTPM]":"19.1","Cell RNA - AN3-CA [nTPM]":"76.4","Cell RNA - ASC diff [nTPM]":"27.1","Cell RNA - ASC TERT1 [nTPM]":"27.9","Cell RNA - BEWO [nTPM]":"31.3","Cell RNA - BJ [nTPM]":"36.0","Cell RNA - BJ hTERT+ [nTPM]":"34.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"51.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"40.5","Cell RNA - CACO-2 [nTPM]":"30.8","Cell RNA - CAPAN-2 [nTPM]":"102.6","Cell RNA - Daudi [nTPM]":"43.6","Cell RNA - EFO-21 [nTPM]":"26.3","Cell RNA - fHDF\/TERT166 [nTPM]":"55.4","Cell RNA - GAMG [nTPM]":"32.4","Cell RNA - HaCaT [nTPM]":"49.8","Cell RNA - HAP1 [nTPM]":"38.3","Cell RNA - HBEC3-KT [nTPM]":"127.3","Cell RNA - HBF TERT88 [nTPM]":"23.1","Cell RNA - HDLM-2 [nTPM]":"33.4","Cell RNA - HEK 293 [nTPM]":"36.3","Cell RNA - HEL [nTPM]":"27.8","Cell RNA - HeLa [nTPM]":"62.5","Cell RNA - Hep G2 [nTPM]":"35.5","Cell RNA - HHSteC [nTPM]":"75.8","Cell RNA - HL-60 [nTPM]":"38.5","Cell RNA - HMC-1 [nTPM]":"67.4","Cell RNA - HSkMC [nTPM]":"26.0","Cell RNA - hTCEpi [nTPM]":"63.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"64.8","Cell RNA - hTERT-HME1 [nTPM]":"63.2","Cell RNA - hTERT-RPE1 [nTPM]":"28.5","Cell RNA - HUVEC TERT2 [nTPM]":"36.4","Cell RNA - JURKAT [nTPM]":"49.2","Cell RNA - K-562 [nTPM]":"24.1","Cell RNA - Karpas-707 [nTPM]":"35.2","Cell RNA - LHCN-M2 [nTPM]":"67.4","Cell RNA - MCF7 [nTPM]":"42.6","Cell RNA - MOLT-4 [nTPM]":"50.4","Cell RNA - NB-4 [nTPM]":"27.3","Cell RNA - NTERA-2 [nTPM]":"43.2","Cell RNA - OE19 [nTPM]":"32.1","Cell RNA - PC-3 [nTPM]":"86.6","Cell RNA - REH [nTPM]":"40.4","Cell RNA - RH-30 [nTPM]":"62.7","Cell RNA - RPMI-8226 [nTPM]":"91.2","Cell RNA - RPTEC TERT1 [nTPM]":"48.3","Cell RNA - RT4 [nTPM]":"25.4","Cell RNA - SCLC-21H [nTPM]":"26.0","Cell RNA - SH-SY5Y [nTPM]":"25.5","Cell RNA - SiHa [nTPM]":"57.4","Cell RNA - SK-BR-3 [nTPM]":"31.1","Cell RNA - SK-MEL-30 [nTPM]":"27.5","Cell RNA - SuSa [nTPM]":"22.1","Cell RNA - T-47d [nTPM]":"35.7","Cell RNA - THP-1 [nTPM]":"21.7","Cell RNA - TIME [nTPM]":"35.8","Cell RNA - U-138 MG [nTPM]":"40.6","Cell RNA - U-2 OS [nTPM]":"54.9","Cell RNA - U-2197 [nTPM]":"85.3","Cell RNA - U-251 MG [nTPM]":"44.9","Cell RNA - U-266\/70 [nTPM]":"47.6","Cell RNA - U-266\/84 [nTPM]":"39.8","Cell RNA - U-698 [nTPM]":"31.4","Cell RNA - U-87 MG [nTPM]":"89.6","Cell RNA - U-937 [nTPM]":"71.3","Cell RNA - WM-115 [nTPM]":"43.6","Blood RNA - basophil [nTPM]":"19.5","Blood RNA - classical monocyte [nTPM]":"23.7","Blood RNA - eosinophil [nTPM]":"19.1","Blood RNA - gdT-cell [nTPM]":"34.6","Blood RNA - intermediate monocyte [nTPM]":"27.1","Blood RNA - MAIT T-cell [nTPM]":"43.0","Blood RNA - memory B-cell [nTPM]":"27.2","Blood RNA - memory CD4 T-cell [nTPM]":"29.5","Blood RNA - memory CD8 T-cell [nTPM]":"35.4","Blood RNA - myeloid DC [nTPM]":"28.3","Blood RNA - naive B-cell [nTPM]":"31.5","Blood RNA - naive CD4 T-cell [nTPM]":"26.8","Blood RNA - naive CD8 T-cell [nTPM]":"34.5","Blood RNA - neutrophil [nTPM]":"3.4","Blood RNA - NK-cell [nTPM]":"30.3","Blood RNA - non-classical monocyte [nTPM]":"27.8","Blood RNA - plasmacytoid DC [nTPM]":"19.1","Blood RNA - T-reg [nTPM]":"30.2","Blood RNA - total PBMC [nTPM]":"27.8","Brain RNA - amygdala [nTPM]":"5.7","Brain RNA - basal ganglia [nTPM]":"6.8","Brain RNA - cerebellum [nTPM]":"6.5","Brain RNA - cerebral cortex [nTPM]":"9.0","Brain RNA - hippocampal formation [nTPM]":"6.6","Brain RNA - hypothalamus [nTPM]":"6.7","Brain RNA - medulla oblongata [nTPM]":"6.0","Brain RNA - midbrain [nTPM]":"6.2","Brain RNA - pons [nTPM]":"6.2","Brain RNA - spinal cord [nTPM]":"6.2","Brain RNA - thalamus [nTPM]":"5.8","Brain RNA - white matter [nTPM]":"6.6","Single Cell Type RNA - Adipocytes [nTPM]":"15.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.0","Single Cell Type RNA - Astrocytes [nTPM]":"3.9","Single Cell Type RNA - B-cells [nTPM]":"20.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"4.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"23.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.3","Single Cell Type RNA - dendritic cells [nTPM]":"19.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"21.2","Single Cell Type RNA - Early spermatids [nTPM]":"49.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.8","Single Cell Type RNA - Endothelial cells [nTPM]":"13.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"14.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"28.7","Single Cell Type RNA - Fibroblasts [nTPM]":"12.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.2","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"9.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"5.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.3","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"8.4","Single Cell Type RNA - Langerhans cells [nTPM]":"10.6","Single Cell Type RNA - Late spermatids [nTPM]":"75.7","Single Cell Type RNA - Leydig cells [nTPM]":"10.8","Single Cell Type RNA - Macrophages [nTPM]":"11.0","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"8.9","Single Cell Type RNA - Muller glia cells [nTPM]":"5.7","Single Cell Type RNA - NK-cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"60.1","Single Cell Type RNA - Paneth cells [nTPM]":"2.7","Single Cell Type RNA - Peritubular cells [nTPM]":"8.6","Single Cell Type RNA - Plasma cells [nTPM]":"59.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.7","Single Cell Type RNA - Spermatocytes [nTPM]":"7.5","Single Cell Type RNA - Spermatogonia [nTPM]":"10.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.7","Single Cell Type RNA - T-cells [nTPM]":"17.0","Single Cell Type RNA - Theca cells [nTPM]":"10.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.4","Single Cell Type RNA - Urothelial cells [nTPM]":"26.5"},{"Gene":"FUCA1","Gene synonym":[],"Ensembl":"ENSG00000179163","Gene description":"Alpha-L-fucosidase 1","Uniprot":["P04066"],"Chromosome":"1","Position":"23845077-23868290","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"181.7","Distal enterocytes":"226.6","Paneth cells":"221.0","Proximal enterocytes":"210.9","Syncytiotrophoblasts":"200.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"165.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046542","HPA056371"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"60000000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA046542":"AB_2679691","HPA056371":"AB_2683108"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.45e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.70e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-3"},"Tissue RNA - adipose tissue [nTPM]":"34.2","Tissue RNA - adrenal gland [nTPM]":"34.4","Tissue RNA - amygdala [nTPM]":"8.3","Tissue RNA - appendix [nTPM]":"49.8","Tissue RNA - basal ganglia [nTPM]":"8.2","Tissue RNA - bone marrow [nTPM]":"7.7","Tissue RNA - breast [nTPM]":"26.3","Tissue RNA - cerebellum [nTPM]":"8.3","Tissue RNA - cerebral cortex [nTPM]":"11.2","Tissue RNA - cervix [nTPM]":"54.5","Tissue RNA - choroid plexus [nTPM]":"23.8","Tissue RNA - colon [nTPM]":"124.2","Tissue RNA - duodenum [nTPM]":"90.3","Tissue RNA - endometrium 1 [nTPM]":"20.7","Tissue RNA - epididymis [nTPM]":"113.0","Tissue RNA - esophagus [nTPM]":"17.0","Tissue RNA - fallopian tube [nTPM]":"51.1","Tissue RNA - gallbladder [nTPM]":"46.6","Tissue RNA - heart muscle [nTPM]":"20.6","Tissue RNA - hippocampal formation [nTPM]":"8.3","Tissue RNA - hypothalamus [nTPM]":"10.5","Tissue RNA - kidney [nTPM]":"78.2","Tissue RNA - liver [nTPM]":"104.8","Tissue RNA - lung [nTPM]":"55.1","Tissue RNA - lymph node [nTPM]":"168.2","Tissue RNA - medulla oblongata [nTPM]":"9.5","Tissue RNA - midbrain [nTPM]":"8.8","Tissue RNA - ovary [nTPM]":"23.8","Tissue RNA - pancreas [nTPM]":"23.9","Tissue RNA - parathyroid gland [nTPM]":"56.9","Tissue RNA - pituitary gland [nTPM]":"17.6","Tissue RNA - placenta [nTPM]":"72.6","Tissue RNA - pons [nTPM]":"9.6","Tissue RNA - prostate [nTPM]":"50.2","Tissue RNA - rectum [nTPM]":"140.7","Tissue RNA - retina [nTPM]":"5.7","Tissue RNA - salivary gland [nTPM]":"40.8","Tissue RNA - seminal vesicle [nTPM]":"60.4","Tissue RNA - skeletal muscle [nTPM]":"15.8","Tissue RNA - skin 1 [nTPM]":"14.9","Tissue RNA - small intestine [nTPM]":"81.3","Tissue RNA - smooth muscle [nTPM]":"26.7","Tissue RNA - spinal cord [nTPM]":"9.3","Tissue RNA - spleen [nTPM]":"71.8","Tissue RNA - stomach 1 [nTPM]":"63.9","Tissue RNA - testis [nTPM]":"27.7","Tissue RNA - thalamus [nTPM]":"10.8","Tissue RNA - thymus [nTPM]":"26.8","Tissue RNA - thyroid gland [nTPM]":"70.6","Tissue RNA - tongue [nTPM]":"17.7","Tissue RNA - tonsil [nTPM]":"94.1","Tissue RNA - urinary bladder [nTPM]":"74.9","Tissue RNA - vagina [nTPM]":"13.2","Tissue RNA - white matter [nTPM]":"12.8","Cell RNA - A-431 [nTPM]":"15.9","Cell RNA - A549 [nTPM]":"10.6","Cell RNA - AF22 [nTPM]":"2.2","Cell RNA - AN3-CA [nTPM]":"31.9","Cell RNA - ASC diff [nTPM]":"4.2","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"11.0","Cell RNA - BJ [nTPM]":"16.6","Cell RNA - BJ hTERT+ [nTPM]":"34.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"31.6","Cell RNA - CACO-2 [nTPM]":"14.5","Cell RNA - CAPAN-2 [nTPM]":"165.1","Cell RNA - Daudi [nTPM]":"23.9","Cell RNA - EFO-21 [nTPM]":"40.9","Cell RNA - fHDF\/TERT166 [nTPM]":"21.3","Cell RNA - GAMG [nTPM]":"18.8","Cell RNA - HaCaT [nTPM]":"9.4","Cell RNA - HAP1 [nTPM]":"15.3","Cell RNA - HBEC3-KT [nTPM]":"35.4","Cell RNA - HBF TERT88 [nTPM]":"22.4","Cell RNA - HDLM-2 [nTPM]":"16.9","Cell RNA - HEK 293 [nTPM]":"25.6","Cell RNA - HEL [nTPM]":"19.7","Cell RNA - HeLa [nTPM]":"9.2","Cell RNA - Hep G2 [nTPM]":"32.7","Cell RNA - HHSteC [nTPM]":"14.2","Cell RNA - HL-60 [nTPM]":"2.0","Cell RNA - HMC-1 [nTPM]":"62.7","Cell RNA - HSkMC [nTPM]":"15.3","Cell RNA - hTCEpi [nTPM]":"19.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.2","Cell RNA - hTERT-HME1 [nTPM]":"8.1","Cell RNA - hTERT-RPE1 [nTPM]":"55.2","Cell RNA - HUVEC TERT2 [nTPM]":"6.9","Cell RNA - JURKAT [nTPM]":"13.3","Cell RNA - K-562 [nTPM]":"9.3","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"20.6","Cell RNA - MCF7 [nTPM]":"17.5","Cell RNA - MOLT-4 [nTPM]":"5.0","Cell RNA - NB-4 [nTPM]":"17.7","Cell RNA - NTERA-2 [nTPM]":"5.4","Cell RNA - OE19 [nTPM]":"48.1","Cell RNA - PC-3 [nTPM]":"16.9","Cell RNA - REH [nTPM]":"26.9","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"26.2","Cell RNA - RPTEC TERT1 [nTPM]":"63.5","Cell RNA - RT4 [nTPM]":"40.5","Cell RNA - SCLC-21H [nTPM]":"10.9","Cell RNA - SH-SY5Y [nTPM]":"10.6","Cell RNA - SiHa [nTPM]":"47.9","Cell RNA - SK-BR-3 [nTPM]":"18.5","Cell RNA - SK-MEL-30 [nTPM]":"26.2","Cell RNA - SuSa [nTPM]":"17.9","Cell RNA - T-47d [nTPM]":"13.6","Cell RNA - THP-1 [nTPM]":"7.8","Cell RNA - TIME [nTPM]":"1.8","Cell RNA - U-138 MG [nTPM]":"5.8","Cell RNA - U-2 OS [nTPM]":"9.0","Cell RNA - U-2197 [nTPM]":"38.9","Cell RNA - U-251 MG [nTPM]":"5.6","Cell RNA - U-266\/70 [nTPM]":"28.5","Cell RNA - U-266\/84 [nTPM]":"31.0","Cell RNA - U-698 [nTPM]":"8.5","Cell RNA - U-87 MG [nTPM]":"14.5","Cell RNA - U-937 [nTPM]":"58.9","Cell RNA - WM-115 [nTPM]":"9.5","Blood RNA - basophil [nTPM]":"54.8","Blood RNA - classical monocyte [nTPM]":"100.4","Blood RNA - eosinophil [nTPM]":"51.9","Blood RNA - gdT-cell [nTPM]":"27.2","Blood RNA - intermediate monocyte [nTPM]":"99.9","Blood RNA - MAIT T-cell [nTPM]":"23.1","Blood RNA - memory B-cell [nTPM]":"23.8","Blood RNA - memory CD4 T-cell [nTPM]":"19.5","Blood RNA - memory CD8 T-cell [nTPM]":"22.9","Blood RNA - myeloid DC [nTPM]":"44.0","Blood RNA - naive B-cell [nTPM]":"14.1","Blood RNA - naive CD4 T-cell [nTPM]":"18.9","Blood RNA - naive CD8 T-cell [nTPM]":"22.0","Blood RNA - neutrophil [nTPM]":"12.8","Blood RNA - NK-cell [nTPM]":"44.6","Blood RNA - non-classical monocyte [nTPM]":"91.1","Blood RNA - plasmacytoid DC [nTPM]":"25.4","Blood RNA - T-reg [nTPM]":"21.4","Blood RNA - total PBMC [nTPM]":"64.8","Brain RNA - amygdala [nTPM]":"8.3","Brain RNA - basal ganglia [nTPM]":"8.2","Brain RNA - cerebellum [nTPM]":"8.3","Brain RNA - cerebral cortex [nTPM]":"11.2","Brain RNA - hippocampal formation [nTPM]":"8.3","Brain RNA - hypothalamus [nTPM]":"10.5","Brain RNA - medulla oblongata [nTPM]":"9.5","Brain RNA - midbrain [nTPM]":"8.8","Brain RNA - pons [nTPM]":"9.6","Brain RNA - spinal cord [nTPM]":"9.3","Brain RNA - thalamus [nTPM]":"10.8","Brain RNA - white matter [nTPM]":"12.8","Single Cell Type RNA - Adipocytes [nTPM]":"12.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"28.6","Single Cell Type RNA - Astrocytes [nTPM]":"4.2","Single Cell Type RNA - B-cells [nTPM]":"10.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"99.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"4.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"40.0","Single Cell Type RNA - Club cells [nTPM]":"77.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"84.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"181.7","Single Cell Type RNA - dendritic cells [nTPM]":"13.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"226.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"64.1","Single Cell Type RNA - Early spermatids [nTPM]":"61.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"31.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.8","Single Cell Type RNA - Endothelial cells [nTPM]":"11.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.8","Single Cell Type RNA - Erythroid cells [nTPM]":"20.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"50.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"24.2","Single Cell Type RNA - Fibroblasts [nTPM]":"16.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"33.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.3","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"11.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.7","Single Cell Type RNA - Hepatocytes [nTPM]":"42.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"156.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"44.4","Single Cell Type RNA - Ionocytes [nTPM]":"44.7","Single Cell Type RNA - Kupffer cells [nTPM]":"121.0","Single Cell Type RNA - Langerhans cells [nTPM]":"13.5","Single Cell Type RNA - Late spermatids [nTPM]":"24.4","Single Cell Type RNA - Leydig cells [nTPM]":"23.3","Single Cell Type RNA - Macrophages [nTPM]":"85.4","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"29.6","Single Cell Type RNA - Muller glia cells [nTPM]":"13.0","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"34.9","Single Cell Type RNA - Paneth cells [nTPM]":"221.0","Single Cell Type RNA - Peritubular cells [nTPM]":"19.5","Single Cell Type RNA - Plasma cells [nTPM]":"8.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"210.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"40.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"53.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.2","Single Cell Type RNA - Spermatocytes [nTPM]":"109.0","Single Cell Type RNA - Spermatogonia [nTPM]":"24.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"200.6","Single Cell Type RNA - T-cells [nTPM]":"11.2","Single Cell Type RNA - Theca cells [nTPM]":"34.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"79.5","Single Cell Type RNA - Urothelial cells [nTPM]":"40.3"},{"Gene":"FUT8","Gene synonym":[],"Ensembl":"ENSG00000033170","Gene description":"Fucosyltransferase 8","Uniprot":["Q9BYC5"],"Chromosome":"14","Position":"65410592-65744121","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"64.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Oligodendrocytes":"1019.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"15.6","NK-cells":"14.8","T-cells":"10.0"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017129","HPA043410"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"CAB017129":null,"HPA043410":"AB_2678467"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-3"},"Tissue RNA - adipose tissue [nTPM]":"7.9","Tissue RNA - adrenal gland [nTPM]":"8.2","Tissue RNA - amygdala [nTPM]":"21.0","Tissue RNA - appendix [nTPM]":"11.9","Tissue RNA - basal ganglia [nTPM]":"38.2","Tissue RNA - bone marrow [nTPM]":"3.6","Tissue RNA - breast [nTPM]":"10.5","Tissue RNA - cerebellum [nTPM]":"44.1","Tissue RNA - cerebral cortex [nTPM]":"28.2","Tissue RNA - cervix [nTPM]":"6.9","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"11.4","Tissue RNA - duodenum [nTPM]":"17.5","Tissue RNA - endometrium 1 [nTPM]":"9.0","Tissue RNA - epididymis [nTPM]":"5.3","Tissue RNA - esophagus [nTPM]":"6.8","Tissue RNA - fallopian tube [nTPM]":"15.6","Tissue RNA - gallbladder [nTPM]":"11.1","Tissue RNA - heart muscle [nTPM]":"4.7","Tissue RNA - hippocampal formation [nTPM]":"20.4","Tissue RNA - hypothalamus [nTPM]":"27.7","Tissue RNA - kidney [nTPM]":"6.9","Tissue RNA - liver [nTPM]":"3.4","Tissue RNA - lung [nTPM]":"8.1","Tissue RNA - lymph node [nTPM]":"11.7","Tissue RNA - medulla oblongata [nTPM]":"32.8","Tissue RNA - midbrain [nTPM]":"29.9","Tissue RNA - ovary [nTPM]":"7.3","Tissue RNA - pancreas [nTPM]":"9.9","Tissue RNA - parathyroid gland [nTPM]":"9.6","Tissue RNA - pituitary gland [nTPM]":"4.6","Tissue RNA - placenta [nTPM]":"17.3","Tissue RNA - pons [nTPM]":"29.3","Tissue RNA - prostate [nTPM]":"5.8","Tissue RNA - rectum [nTPM]":"11.6","Tissue RNA - retina [nTPM]":"8.3","Tissue RNA - salivary gland [nTPM]":"42.6","Tissue RNA - seminal vesicle [nTPM]":"10.5","Tissue RNA - skeletal muscle [nTPM]":"2.5","Tissue RNA - skin 1 [nTPM]":"5.3","Tissue RNA - small intestine [nTPM]":"17.4","Tissue RNA - smooth muscle [nTPM]":"11.0","Tissue RNA - spinal cord [nTPM]":"29.4","Tissue RNA - spleen [nTPM]":"10.2","Tissue RNA - stomach 1 [nTPM]":"31.8","Tissue RNA - testis [nTPM]":"16.4","Tissue RNA - thalamus [nTPM]":"29.7","Tissue RNA - thymus [nTPM]":"11.3","Tissue RNA - thyroid gland [nTPM]":"8.4","Tissue RNA - tongue [nTPM]":"6.3","Tissue RNA - tonsil [nTPM]":"18.6","Tissue RNA - urinary bladder [nTPM]":"13.3","Tissue RNA - vagina [nTPM]":"4.5","Tissue RNA - white matter [nTPM]":"64.3","Cell RNA - A-431 [nTPM]":"115.9","Cell RNA - A549 [nTPM]":"22.5","Cell RNA - AF22 [nTPM]":"12.6","Cell RNA - AN3-CA [nTPM]":"110.6","Cell RNA - ASC diff [nTPM]":"49.5","Cell RNA - ASC TERT1 [nTPM]":"38.4","Cell RNA - BEWO [nTPM]":"61.6","Cell RNA - BJ [nTPM]":"35.9","Cell RNA - BJ hTERT+ [nTPM]":"64.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"30.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"32.6","Cell RNA - CACO-2 [nTPM]":"16.9","Cell RNA - CAPAN-2 [nTPM]":"44.8","Cell RNA - Daudi [nTPM]":"30.7","Cell RNA - EFO-21 [nTPM]":"29.2","Cell RNA - fHDF\/TERT166 [nTPM]":"40.1","Cell RNA - GAMG [nTPM]":"79.4","Cell RNA - HaCaT [nTPM]":"9.0","Cell RNA - HAP1 [nTPM]":"29.9","Cell RNA - HBEC3-KT [nTPM]":"11.4","Cell RNA - HBF TERT88 [nTPM]":"45.6","Cell RNA - HDLM-2 [nTPM]":"124.2","Cell RNA - HEK 293 [nTPM]":"11.0","Cell RNA - HEL [nTPM]":"33.5","Cell RNA - HeLa [nTPM]":"7.2","Cell RNA - Hep G2 [nTPM]":"23.0","Cell RNA - HHSteC [nTPM]":"26.8","Cell RNA - HL-60 [nTPM]":"7.6","Cell RNA - HMC-1 [nTPM]":"23.9","Cell RNA - HSkMC [nTPM]":"96.0","Cell RNA - hTCEpi [nTPM]":"6.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"39.3","Cell RNA - hTERT-HME1 [nTPM]":"19.4","Cell RNA - hTERT-RPE1 [nTPM]":"124.4","Cell RNA - HUVEC TERT2 [nTPM]":"69.6","Cell RNA - JURKAT [nTPM]":"17.1","Cell RNA - K-562 [nTPM]":"14.1","Cell RNA - Karpas-707 [nTPM]":"28.8","Cell RNA - LHCN-M2 [nTPM]":"20.8","Cell RNA - MCF7 [nTPM]":"60.8","Cell RNA - MOLT-4 [nTPM]":"36.6","Cell RNA - NB-4 [nTPM]":"16.7","Cell RNA - NTERA-2 [nTPM]":"14.7","Cell RNA - OE19 [nTPM]":"59.6","Cell RNA - PC-3 [nTPM]":"66.6","Cell RNA - REH [nTPM]":"26.9","Cell RNA - RH-30 [nTPM]":"10.3","Cell RNA - RPMI-8226 [nTPM]":"17.2","Cell RNA - RPTEC TERT1 [nTPM]":"46.5","Cell RNA - RT4 [nTPM]":"33.1","Cell RNA - SCLC-21H [nTPM]":"23.4","Cell RNA - SH-SY5Y [nTPM]":"16.6","Cell RNA - SiHa [nTPM]":"20.8","Cell RNA - SK-BR-3 [nTPM]":"9.8","Cell RNA - SK-MEL-30 [nTPM]":"8.0","Cell RNA - SuSa [nTPM]":"70.6","Cell RNA - T-47d [nTPM]":"10.2","Cell RNA - THP-1 [nTPM]":"12.9","Cell RNA - TIME [nTPM]":"141.8","Cell RNA - U-138 MG [nTPM]":"34.5","Cell RNA - U-2 OS [nTPM]":"36.0","Cell RNA - U-2197 [nTPM]":"15.3","Cell RNA - U-251 MG [nTPM]":"30.5","Cell RNA - U-266\/70 [nTPM]":"47.3","Cell RNA - U-266\/84 [nTPM]":"18.5","Cell RNA - U-698 [nTPM]":"74.3","Cell RNA - U-87 MG [nTPM]":"68.6","Cell RNA - U-937 [nTPM]":"13.6","Cell RNA - WM-115 [nTPM]":"11.1","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"2.0","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"3.6","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"3.8","Blood RNA - memory B-cell [nTPM]":"15.6","Blood RNA - memory CD4 T-cell [nTPM]":"6.2","Blood RNA - memory CD8 T-cell [nTPM]":"5.6","Blood RNA - myeloid DC [nTPM]":"2.6","Blood RNA - naive B-cell [nTPM]":"8.3","Blood RNA - naive CD4 T-cell [nTPM]":"6.6","Blood RNA - naive CD8 T-cell [nTPM]":"6.6","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"14.8","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"2.6","Blood RNA - T-reg [nTPM]":"10.0","Blood RNA - total PBMC [nTPM]":"2.9","Brain RNA - amygdala [nTPM]":"21.0","Brain RNA - basal ganglia [nTPM]":"38.2","Brain RNA - cerebellum [nTPM]":"44.1","Brain RNA - cerebral cortex [nTPM]":"28.2","Brain RNA - hippocampal formation [nTPM]":"20.4","Brain RNA - hypothalamus [nTPM]":"27.7","Brain RNA - medulla oblongata [nTPM]":"32.8","Brain RNA - midbrain [nTPM]":"29.9","Brain RNA - pons [nTPM]":"29.3","Brain RNA - spinal cord [nTPM]":"29.4","Brain RNA - thalamus [nTPM]":"29.7","Brain RNA - white matter [nTPM]":"64.3","Single Cell Type RNA - Adipocytes [nTPM]":"19.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"32.5","Single Cell Type RNA - Astrocytes [nTPM]":"227.5","Single Cell Type RNA - B-cells [nTPM]":"43.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Bipolar cells [nTPM]":"10.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"18.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"45.5","Single Cell Type RNA - dendritic cells [nTPM]":"8.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"9.1","Single Cell Type RNA - Early spermatids [nTPM]":"37.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.6","Single Cell Type RNA - Endothelial cells [nTPM]":"16.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"15.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"169.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"31.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"28.1","Single Cell Type RNA - Fibroblasts [nTPM]":"22.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"78.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.2","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"3.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"3.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.0","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"166.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.5","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"12.2","Single Cell Type RNA - Langerhans cells [nTPM]":"8.6","Single Cell Type RNA - Late spermatids [nTPM]":"15.3","Single Cell Type RNA - Leydig cells [nTPM]":"12.8","Single Cell Type RNA - Macrophages [nTPM]":"10.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"70.3","Single Cell Type RNA - monocytes [nTPM]":"3.6","Single Cell Type RNA - Muller glia cells [nTPM]":"27.8","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"138.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1019.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"54.7","Single Cell Type RNA - Paneth cells [nTPM]":"10.3","Single Cell Type RNA - Peritubular cells [nTPM]":"13.5","Single Cell Type RNA - Plasma cells [nTPM]":"124.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.2","Single Cell Type RNA - Spermatocytes [nTPM]":"34.6","Single Cell Type RNA - Spermatogonia [nTPM]":"26.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.1","Single Cell Type RNA - T-cells [nTPM]":"18.9","Single Cell Type RNA - Theca cells [nTPM]":"10.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"21.7","Single Cell Type RNA - Urothelial cells [nTPM]":"7.2"},{"Gene":"FXN","Gene synonym":["CyaY","FA","FARR","FRDA","X25"],"Ensembl":"ENSG00000165060","Gene description":"Frataxin","Uniprot":["Q16595"],"Chromosome":"9","Position":"69035751-69079076","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Heme biosynthesis","Ion transport","Iron storage","Iron transport","Transport"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"69.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022164","HPA068304"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB022164":null,"HPA068304":"AB_2685970"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.3","Tissue RNA - adrenal gland [nTPM]":"20.1","Tissue RNA - amygdala [nTPM]":"8.9","Tissue RNA - appendix [nTPM]":"7.8","Tissue RNA - basal ganglia [nTPM]":"9.2","Tissue RNA - bone marrow [nTPM]":"29.1","Tissue RNA - breast [nTPM]":"10.1","Tissue RNA - cerebellum [nTPM]":"9.7","Tissue RNA - cerebral cortex [nTPM]":"8.9","Tissue RNA - cervix [nTPM]":"9.3","Tissue RNA - choroid plexus [nTPM]":"11.7","Tissue RNA - colon [nTPM]":"10.4","Tissue RNA - duodenum [nTPM]":"7.4","Tissue RNA - endometrium 1 [nTPM]":"12.1","Tissue RNA - epididymis [nTPM]":"12.1","Tissue RNA - esophagus [nTPM]":"9.5","Tissue RNA - fallopian tube [nTPM]":"10.2","Tissue RNA - gallbladder [nTPM]":"5.3","Tissue RNA - heart muscle [nTPM]":"27.0","Tissue RNA - hippocampal formation [nTPM]":"9.0","Tissue RNA - hypothalamus [nTPM]":"10.4","Tissue RNA - kidney [nTPM]":"12.9","Tissue RNA - liver [nTPM]":"46.3","Tissue RNA - lung [nTPM]":"7.1","Tissue RNA - lymph node [nTPM]":"9.8","Tissue RNA - medulla oblongata [nTPM]":"9.8","Tissue RNA - midbrain [nTPM]":"10.2","Tissue RNA - ovary [nTPM]":"17.6","Tissue RNA - pancreas [nTPM]":"15.1","Tissue RNA - parathyroid gland [nTPM]":"22.2","Tissue RNA - pituitary gland [nTPM]":"8.1","Tissue RNA - placenta [nTPM]":"9.1","Tissue RNA - pons [nTPM]":"9.8","Tissue RNA - prostate [nTPM]":"10.2","Tissue RNA - rectum [nTPM]":"12.3","Tissue RNA - retina [nTPM]":"4.1","Tissue RNA - salivary gland [nTPM]":"11.7","Tissue RNA - seminal vesicle [nTPM]":"13.6","Tissue RNA - skeletal muscle [nTPM]":"25.5","Tissue RNA - skin 1 [nTPM]":"5.2","Tissue RNA - small intestine [nTPM]":"7.7","Tissue RNA - smooth muscle [nTPM]":"13.3","Tissue RNA - spinal cord [nTPM]":"9.5","Tissue RNA - spleen [nTPM]":"12.6","Tissue RNA - stomach 1 [nTPM]":"10.1","Tissue RNA - testis [nTPM]":"10.7","Tissue RNA - thalamus [nTPM]":"9.9","Tissue RNA - thymus [nTPM]":"5.4","Tissue RNA - thyroid gland [nTPM]":"10.4","Tissue RNA - tongue [nTPM]":"19.8","Tissue RNA - tonsil [nTPM]":"10.4","Tissue RNA - urinary bladder [nTPM]":"12.3","Tissue RNA - vagina [nTPM]":"7.9","Tissue RNA - white matter [nTPM]":"10.4","Cell RNA - A-431 [nTPM]":"27.0","Cell RNA - A549 [nTPM]":"22.1","Cell RNA - AF22 [nTPM]":"34.2","Cell RNA - AN3-CA [nTPM]":"17.0","Cell RNA - ASC diff [nTPM]":"15.7","Cell RNA - ASC TERT1 [nTPM]":"23.1","Cell RNA - BEWO [nTPM]":"34.3","Cell RNA - BJ [nTPM]":"18.6","Cell RNA - BJ hTERT+ [nTPM]":"16.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"28.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.2","Cell RNA - CACO-2 [nTPM]":"11.8","Cell RNA - CAPAN-2 [nTPM]":"16.6","Cell RNA - Daudi [nTPM]":"45.9","Cell RNA - EFO-21 [nTPM]":"14.0","Cell RNA - fHDF\/TERT166 [nTPM]":"19.5","Cell RNA - GAMG [nTPM]":"28.8","Cell RNA - HaCaT [nTPM]":"28.6","Cell RNA - HAP1 [nTPM]":"41.8","Cell RNA - HBEC3-KT [nTPM]":"42.6","Cell RNA - HBF TERT88 [nTPM]":"34.9","Cell RNA - HDLM-2 [nTPM]":"53.9","Cell RNA - HEK 293 [nTPM]":"47.5","Cell RNA - HEL [nTPM]":"66.2","Cell RNA - HeLa [nTPM]":"14.1","Cell RNA - Hep G2 [nTPM]":"87.2","Cell RNA - HHSteC [nTPM]":"26.7","Cell RNA - HL-60 [nTPM]":"48.7","Cell RNA - HMC-1 [nTPM]":"27.7","Cell RNA - HSkMC [nTPM]":"25.7","Cell RNA - hTCEpi [nTPM]":"33.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"27.8","Cell RNA - hTERT-HME1 [nTPM]":"29.9","Cell RNA - hTERT-RPE1 [nTPM]":"9.6","Cell RNA - HUVEC TERT2 [nTPM]":"37.7","Cell RNA - JURKAT [nTPM]":"28.0","Cell RNA - K-562 [nTPM]":"50.3","Cell RNA - Karpas-707 [nTPM]":"43.9","Cell RNA - LHCN-M2 [nTPM]":"26.1","Cell RNA - MCF7 [nTPM]":"25.6","Cell RNA - MOLT-4 [nTPM]":"14.0","Cell RNA - NB-4 [nTPM]":"21.0","Cell RNA - NTERA-2 [nTPM]":"47.5","Cell RNA - OE19 [nTPM]":"53.1","Cell RNA - PC-3 [nTPM]":"42.8","Cell RNA - REH [nTPM]":"32.7","Cell RNA - RH-30 [nTPM]":"24.0","Cell RNA - RPMI-8226 [nTPM]":"32.0","Cell RNA - RPTEC TERT1 [nTPM]":"32.2","Cell RNA - RT4 [nTPM]":"21.5","Cell RNA - SCLC-21H [nTPM]":"26.9","Cell RNA - SH-SY5Y [nTPM]":"12.1","Cell RNA - SiHa [nTPM]":"19.2","Cell RNA - SK-BR-3 [nTPM]":"12.5","Cell RNA - SK-MEL-30 [nTPM]":"20.7","Cell RNA - SuSa [nTPM]":"24.3","Cell RNA - T-47d [nTPM]":"14.1","Cell RNA - THP-1 [nTPM]":"14.4","Cell RNA - TIME [nTPM]":"22.7","Cell RNA - U-138 MG [nTPM]":"18.0","Cell RNA - U-2 OS [nTPM]":"32.0","Cell RNA - U-2197 [nTPM]":"24.1","Cell RNA - U-251 MG [nTPM]":"27.6","Cell RNA - U-266\/70 [nTPM]":"11.6","Cell RNA - U-266\/84 [nTPM]":"11.4","Cell RNA - U-698 [nTPM]":"27.8","Cell RNA - U-87 MG [nTPM]":"8.5","Cell RNA - U-937 [nTPM]":"39.7","Cell RNA - WM-115 [nTPM]":"18.5","Blood RNA - basophil [nTPM]":"8.1","Blood RNA - classical monocyte [nTPM]":"39.9","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"48.6","Blood RNA - intermediate monocyte [nTPM]":"45.4","Blood RNA - MAIT T-cell [nTPM]":"37.5","Blood RNA - memory B-cell [nTPM]":"36.3","Blood RNA - memory CD4 T-cell [nTPM]":"48.0","Blood RNA - memory CD8 T-cell [nTPM]":"48.4","Blood RNA - myeloid DC [nTPM]":"42.8","Blood RNA - naive B-cell [nTPM]":"22.7","Blood RNA - naive CD4 T-cell [nTPM]":"61.6","Blood RNA - naive CD8 T-cell [nTPM]":"59.8","Blood RNA - neutrophil [nTPM]":"1.9","Blood RNA - NK-cell [nTPM]":"60.8","Blood RNA - non-classical monocyte [nTPM]":"36.2","Blood RNA - plasmacytoid DC [nTPM]":"33.2","Blood RNA - T-reg [nTPM]":"43.3","Blood RNA - total PBMC [nTPM]":"49.5","Brain RNA - amygdala [nTPM]":"8.9","Brain RNA - basal ganglia [nTPM]":"9.2","Brain RNA - cerebellum [nTPM]":"9.7","Brain RNA - cerebral cortex [nTPM]":"8.9","Brain RNA - hippocampal formation [nTPM]":"9.0","Brain RNA - hypothalamus [nTPM]":"10.4","Brain RNA - medulla oblongata [nTPM]":"9.8","Brain RNA - midbrain [nTPM]":"10.2","Brain RNA - pons [nTPM]":"9.8","Brain RNA - spinal cord [nTPM]":"9.5","Brain RNA - thalamus [nTPM]":"9.9","Brain RNA - white matter [nTPM]":"10.4","Single Cell Type RNA - Adipocytes [nTPM]":"11.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.5","Single Cell Type RNA - Astrocytes [nTPM]":"13.1","Single Cell Type RNA - B-cells [nTPM]":"19.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"19.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"36.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"6.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"38.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"10.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"39.9","Single Cell Type RNA - dendritic cells [nTPM]":"14.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"17.5","Single Cell Type RNA - Early spermatids [nTPM]":"2.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.5","Single Cell Type RNA - Endothelial cells [nTPM]":"16.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"56.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"22.3","Single Cell Type RNA - Fibroblasts [nTPM]":"14.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.7","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"15.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"69.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"33.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.3","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"22.1","Single Cell Type RNA - Langerhans cells [nTPM]":"16.1","Single Cell Type RNA - Late spermatids [nTPM]":"6.3","Single Cell Type RNA - Leydig cells [nTPM]":"15.8","Single Cell Type RNA - Macrophages [nTPM]":"13.9","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"18.3","Single Cell Type RNA - Muller glia cells [nTPM]":"7.6","Single Cell Type RNA - NK-cells [nTPM]":"28.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.0","Single Cell Type RNA - Paneth cells [nTPM]":"3.7","Single Cell Type RNA - Peritubular cells [nTPM]":"13.2","Single Cell Type RNA - Plasma cells [nTPM]":"42.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"27.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.8","Single Cell Type RNA - Spermatocytes [nTPM]":"5.1","Single Cell Type RNA - Spermatogonia [nTPM]":"32.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"29.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.6","Single Cell Type RNA - T-cells [nTPM]":"17.1","Single Cell Type RNA - Theca cells [nTPM]":"27.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.5","Single Cell Type RNA - Urothelial cells [nTPM]":"14.1"},{"Gene":"FZD2","Gene synonym":[],"Ensembl":"ENSG00000180340","Gene description":"Frizzled class receptor 2","Uniprot":["Q14332"],"Chromosome":"17","Position":"44557484-44561262","Protein class":["Cancer-related genes","Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Developmental protein","G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"10.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"19.2","Kupffer cells":"9.8","Leydig cells":"23.3","Peritubular cells":"18.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"1.1","myeloid DC":"1.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"dendritic cells":"1.8","monocytes":"1.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+ SV40 Large T+":"53.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057667"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA057667":"AB_2683497"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-3"},"Tissue RNA - adipose tissue [nTPM]":"1.5","Tissue RNA - adrenal gland [nTPM]":"1.6","Tissue RNA - amygdala [nTPM]":"1.0","Tissue RNA - appendix [nTPM]":"1.4","Tissue RNA - basal ganglia [nTPM]":"1.5","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"1.3","Tissue RNA - cerebellum [nTPM]":"0.9","Tissue RNA - cerebral cortex [nTPM]":"1.2","Tissue RNA - cervix [nTPM]":"5.9","Tissue RNA - choroid plexus [nTPM]":"10.5","Tissue RNA - colon [nTPM]":"1.8","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"5.3","Tissue RNA - epididymis [nTPM]":"1.3","Tissue RNA - esophagus [nTPM]":"0.9","Tissue RNA - fallopian tube [nTPM]":"3.8","Tissue RNA - gallbladder [nTPM]":"1.8","Tissue RNA - heart muscle [nTPM]":"2.8","Tissue RNA - hippocampal formation [nTPM]":"1.1","Tissue RNA - hypothalamus [nTPM]":"1.3","Tissue RNA - kidney [nTPM]":"2.8","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"2.9","Tissue RNA - lymph node [nTPM]":"0.8","Tissue RNA - medulla oblongata [nTPM]":"1.3","Tissue RNA - midbrain [nTPM]":"1.9","Tissue RNA - ovary [nTPM]":"3.3","Tissue RNA - pancreas [nTPM]":"1.5","Tissue RNA - parathyroid gland [nTPM]":"2.1","Tissue RNA - pituitary gland [nTPM]":"1.1","Tissue RNA - placenta [nTPM]":"3.6","Tissue RNA - pons [nTPM]":"2.0","Tissue RNA - prostate [nTPM]":"1.7","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"0.7","Tissue RNA - salivary gland [nTPM]":"1.0","Tissue RNA - seminal vesicle [nTPM]":"1.9","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"1.6","Tissue RNA - smooth muscle [nTPM]":"1.5","Tissue RNA - spinal cord [nTPM]":"1.3","Tissue RNA - spleen [nTPM]":"2.1","Tissue RNA - stomach 1 [nTPM]":"1.2","Tissue RNA - testis [nTPM]":"1.5","Tissue RNA - thalamus [nTPM]":"1.4","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"2.4","Tissue RNA - tongue [nTPM]":"0.7","Tissue RNA - tonsil [nTPM]":"0.7","Tissue RNA - urinary bladder [nTPM]":"2.0","Tissue RNA - vagina [nTPM]":"2.5","Tissue RNA - white matter [nTPM]":"1.6","Cell RNA - A-431 [nTPM]":"12.9","Cell RNA - A549 [nTPM]":"37.7","Cell RNA - AF22 [nTPM]":"38.3","Cell RNA - AN3-CA [nTPM]":"13.8","Cell RNA - ASC diff [nTPM]":"8.7","Cell RNA - ASC TERT1 [nTPM]":"6.4","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"39.5","Cell RNA - BJ hTERT+ [nTPM]":"30.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"53.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"38.2","Cell RNA - CACO-2 [nTPM]":"28.4","Cell RNA - CAPAN-2 [nTPM]":"6.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"8.9","Cell RNA - fHDF\/TERT166 [nTPM]":"13.9","Cell RNA - GAMG [nTPM]":"13.1","Cell RNA - HaCaT [nTPM]":"5.5","Cell RNA - HAP1 [nTPM]":"3.6","Cell RNA - HBEC3-KT [nTPM]":"2.8","Cell RNA - HBF TERT88 [nTPM]":"30.2","Cell RNA - HDLM-2 [nTPM]":"2.9","Cell RNA - HEK 293 [nTPM]":"7.2","Cell RNA - HEL [nTPM]":"1.7","Cell RNA - HeLa [nTPM]":"6.6","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"7.7","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"7.5","Cell RNA - HSkMC [nTPM]":"10.7","Cell RNA - hTCEpi [nTPM]":"2.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.6","Cell RNA - hTERT-HME1 [nTPM]":"8.8","Cell RNA - hTERT-RPE1 [nTPM]":"40.8","Cell RNA - HUVEC TERT2 [nTPM]":"1.8","Cell RNA - JURKAT [nTPM]":"4.9","Cell RNA - K-562 [nTPM]":"2.5","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"20.9","Cell RNA - MCF7 [nTPM]":"5.9","Cell RNA - MOLT-4 [nTPM]":"6.7","Cell RNA - NB-4 [nTPM]":"3.6","Cell RNA - NTERA-2 [nTPM]":"26.8","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"6.7","Cell RNA - REH [nTPM]":"18.1","Cell RNA - RH-30 [nTPM]":"8.6","Cell RNA - RPMI-8226 [nTPM]":"1.9","Cell RNA - RPTEC TERT1 [nTPM]":"7.7","Cell RNA - RT4 [nTPM]":"0.6","Cell RNA - SCLC-21H [nTPM]":"3.8","Cell RNA - SH-SY5Y [nTPM]":"10.9","Cell RNA - SiHa [nTPM]":"5.2","Cell RNA - SK-BR-3 [nTPM]":"1.1","Cell RNA - SK-MEL-30 [nTPM]":"2.3","Cell RNA - SuSa [nTPM]":"32.4","Cell RNA - T-47d [nTPM]":"14.6","Cell RNA - THP-1 [nTPM]":"8.4","Cell RNA - TIME [nTPM]":"0.7","Cell RNA - U-138 MG [nTPM]":"24.1","Cell RNA - U-2 OS [nTPM]":"17.5","Cell RNA - U-2197 [nTPM]":"4.4","Cell RNA - U-251 MG [nTPM]":"22.6","Cell RNA - U-266\/70 [nTPM]":"0.8","Cell RNA - U-266\/84 [nTPM]":"0.7","Cell RNA - U-698 [nTPM]":"3.0","Cell RNA - U-87 MG [nTPM]":"4.0","Cell RNA - U-937 [nTPM]":"2.4","Cell RNA - WM-115 [nTPM]":"11.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"1.8","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"1.0","Brain RNA - basal ganglia [nTPM]":"1.5","Brain RNA - cerebellum [nTPM]":"0.9","Brain RNA - cerebral cortex [nTPM]":"1.2","Brain RNA - hippocampal formation [nTPM]":"1.1","Brain RNA - hypothalamus [nTPM]":"1.3","Brain RNA - medulla oblongata [nTPM]":"1.3","Brain RNA - midbrain [nTPM]":"1.9","Brain RNA - pons [nTPM]":"2.0","Brain RNA - spinal cord [nTPM]":"1.3","Brain RNA - thalamus [nTPM]":"1.4","Brain RNA - white matter [nTPM]":"1.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.6","Single Cell Type RNA - dendritic cells [nTPM]":"1.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"5.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"9.8","Single Cell Type RNA - Langerhans cells [nTPM]":"6.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.4","Single Cell Type RNA - Leydig cells [nTPM]":"23.3","Single Cell Type RNA - Macrophages [nTPM]":"5.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"6.2","Single Cell Type RNA - Muller glia cells [nTPM]":"6.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"18.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.3","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"2.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"FZD4","Gene synonym":["CD344","EVR1"],"Ensembl":"ENSG00000174804","Gene description":"Frizzled class receptor 4","Uniprot":["Q9ULV1"],"Chromosome":"11","Position":"86945679-86955395","Protein class":["CD markers","Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Developmental protein","G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"120.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"83.0","Collecting duct cells":"36.8","Endothelial cells":"51.2","Hepatic stellate cells":"99.6","Sertoli cells":"32.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"22.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"63.6","Hep G2":"85.2","HSkMC":"46.0","HUVEC TERT2":"93.6","TIME":"46.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042328","HPA074833"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA042328":"AB_10962494","HPA074833":"AB_2686716"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.60e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Tissue RNA - adipose tissue [nTPM]":"120.1","Tissue RNA - adrenal gland [nTPM]":"9.5","Tissue RNA - amygdala [nTPM]":"6.7","Tissue RNA - appendix [nTPM]":"5.8","Tissue RNA - basal ganglia [nTPM]":"6.2","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"55.6","Tissue RNA - cerebellum [nTPM]":"5.1","Tissue RNA - cerebral cortex [nTPM]":"7.3","Tissue RNA - cervix [nTPM]":"12.5","Tissue RNA - choroid plexus [nTPM]":"7.8","Tissue RNA - colon [nTPM]":"14.9","Tissue RNA - duodenum [nTPM]":"2.8","Tissue RNA - endometrium 1 [nTPM]":"12.2","Tissue RNA - epididymis [nTPM]":"7.6","Tissue RNA - esophagus [nTPM]":"6.5","Tissue RNA - fallopian tube [nTPM]":"16.3","Tissue RNA - gallbladder [nTPM]":"11.5","Tissue RNA - heart muscle [nTPM]":"27.4","Tissue RNA - hippocampal formation [nTPM]":"5.6","Tissue RNA - hypothalamus [nTPM]":"5.9","Tissue RNA - kidney [nTPM]":"27.1","Tissue RNA - liver [nTPM]":"14.6","Tissue RNA - lung [nTPM]":"32.9","Tissue RNA - lymph node [nTPM]":"6.2","Tissue RNA - medulla oblongata [nTPM]":"6.5","Tissue RNA - midbrain [nTPM]":"6.3","Tissue RNA - ovary [nTPM]":"12.9","Tissue RNA - pancreas [nTPM]":"9.5","Tissue RNA - parathyroid gland [nTPM]":"6.4","Tissue RNA - pituitary gland [nTPM]":"8.7","Tissue RNA - placenta [nTPM]":"11.7","Tissue RNA - pons [nTPM]":"7.0","Tissue RNA - prostate [nTPM]":"12.5","Tissue RNA - rectum [nTPM]":"6.3","Tissue RNA - retina [nTPM]":"1.1","Tissue RNA - salivary gland [nTPM]":"12.2","Tissue RNA - seminal vesicle [nTPM]":"30.2","Tissue RNA - skeletal muscle [nTPM]":"31.5","Tissue RNA - skin 1 [nTPM]":"5.9","Tissue RNA - small intestine [nTPM]":"8.8","Tissue RNA - smooth muscle [nTPM]":"13.4","Tissue RNA - spinal cord [nTPM]":"5.6","Tissue RNA - spleen [nTPM]":"14.1","Tissue RNA - stomach 1 [nTPM]":"14.1","Tissue RNA - testis [nTPM]":"5.1","Tissue RNA - thalamus [nTPM]":"8.5","Tissue RNA - thymus [nTPM]":"3.9","Tissue RNA - thyroid gland [nTPM]":"18.1","Tissue RNA - tongue [nTPM]":"40.6","Tissue RNA - tonsil [nTPM]":"4.6","Tissue RNA - urinary bladder [nTPM]":"10.5","Tissue RNA - vagina [nTPM]":"9.5","Tissue RNA - white matter [nTPM]":"5.9","Cell RNA - A-431 [nTPM]":"1.3","Cell RNA - A549 [nTPM]":"1.1","Cell RNA - AF22 [nTPM]":"2.7","Cell RNA - AN3-CA [nTPM]":"5.2","Cell RNA - ASC diff [nTPM]":"63.6","Cell RNA - ASC TERT1 [nTPM]":"16.5","Cell RNA - BEWO [nTPM]":"3.7","Cell RNA - BJ [nTPM]":"8.4","Cell RNA - BJ hTERT+ [nTPM]":"7.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.3","Cell RNA - CACO-2 [nTPM]":"7.1","Cell RNA - CAPAN-2 [nTPM]":"0.9","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.8","Cell RNA - fHDF\/TERT166 [nTPM]":"2.6","Cell RNA - GAMG [nTPM]":"4.4","Cell RNA - HaCaT [nTPM]":"2.8","Cell RNA - HAP1 [nTPM]":"3.1","Cell RNA - HBEC3-KT [nTPM]":"1.3","Cell RNA - HBF TERT88 [nTPM]":"2.5","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"2.1","Cell RNA - HEL [nTPM]":"2.8","Cell RNA - HeLa [nTPM]":"2.3","Cell RNA - Hep G2 [nTPM]":"85.2","Cell RNA - HHSteC [nTPM]":"18.9","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"46.0","Cell RNA - hTCEpi [nTPM]":"0.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.8","Cell RNA - hTERT-HME1 [nTPM]":"0.5","Cell RNA - hTERT-RPE1 [nTPM]":"7.5","Cell RNA - HUVEC TERT2 [nTPM]":"93.6","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"3.9","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"2.2","Cell RNA - MCF7 [nTPM]":"2.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"3.9","Cell RNA - OE19 [nTPM]":"7.5","Cell RNA - PC-3 [nTPM]":"18.8","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"4.8","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"9.0","Cell RNA - RT4 [nTPM]":"13.7","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"0.8","Cell RNA - SiHa [nTPM]":"3.5","Cell RNA - SK-BR-3 [nTPM]":"1.0","Cell RNA - SK-MEL-30 [nTPM]":"1.4","Cell RNA - SuSa [nTPM]":"5.6","Cell RNA - T-47d [nTPM]":"12.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"46.3","Cell RNA - U-138 MG [nTPM]":"7.8","Cell RNA - U-2 OS [nTPM]":"5.1","Cell RNA - U-2197 [nTPM]":"9.2","Cell RNA - U-251 MG [nTPM]":"1.7","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"1.3","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"2.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"6.7","Brain RNA - basal ganglia [nTPM]":"6.2","Brain RNA - cerebellum [nTPM]":"5.1","Brain RNA - cerebral cortex [nTPM]":"7.3","Brain RNA - hippocampal formation [nTPM]":"5.6","Brain RNA - hypothalamus [nTPM]":"5.9","Brain RNA - medulla oblongata [nTPM]":"6.5","Brain RNA - midbrain [nTPM]":"6.3","Brain RNA - pons [nTPM]":"7.0","Brain RNA - spinal cord [nTPM]":"5.6","Brain RNA - thalamus [nTPM]":"8.5","Brain RNA - white matter [nTPM]":"5.9","Single Cell Type RNA - Adipocytes [nTPM]":"83.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.3","Single Cell Type RNA - Astrocytes [nTPM]":"9.8","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"2.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.7","Single Cell Type RNA - Endothelial cells [nTPM]":"51.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"17.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"9.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"99.6","Single Cell Type RNA - Hepatocytes [nTPM]":"14.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"6.7","Single Cell Type RNA - Langerhans cells [nTPM]":"1.8","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"9.3","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"3.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"16.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"FZD6","Gene synonym":["Hfz6"],"Ensembl":"ENSG00000164930","Gene description":"Frizzled class receptor 6","Uniprot":["O60353"],"Chromosome":"8","Position":"103298433-103332866","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Developmental protein","G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Glandular and luminal cells":"73.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"NK-cell":"4.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"NK-cells":"4.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTCEpi":"127.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017991"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA017991":"AB_1849138"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.20e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.7","Tissue RNA - adrenal gland [nTPM]":"10.6","Tissue RNA - amygdala [nTPM]":"3.0","Tissue RNA - appendix [nTPM]":"4.2","Tissue RNA - basal ganglia [nTPM]":"2.8","Tissue RNA - bone marrow [nTPM]":"1.0","Tissue RNA - breast [nTPM]":"15.1","Tissue RNA - cerebellum [nTPM]":"3.1","Tissue RNA - cerebral cortex [nTPM]":"4.3","Tissue RNA - cervix [nTPM]":"14.2","Tissue RNA - choroid plexus [nTPM]":"5.7","Tissue RNA - colon [nTPM]":"7.0","Tissue RNA - duodenum [nTPM]":"5.7","Tissue RNA - endometrium 1 [nTPM]":"13.0","Tissue RNA - epididymis [nTPM]":"9.5","Tissue RNA - esophagus [nTPM]":"18.7","Tissue RNA - fallopian tube [nTPM]":"23.5","Tissue RNA - gallbladder [nTPM]":"10.6","Tissue RNA - heart muscle [nTPM]":"9.1","Tissue RNA - hippocampal formation [nTPM]":"2.9","Tissue RNA - hypothalamus [nTPM]":"3.0","Tissue RNA - kidney [nTPM]":"14.5","Tissue RNA - liver [nTPM]":"4.0","Tissue RNA - lung [nTPM]":"18.6","Tissue RNA - lymph node [nTPM]":"5.1","Tissue RNA - medulla oblongata [nTPM]":"3.8","Tissue RNA - midbrain [nTPM]":"3.1","Tissue RNA - ovary [nTPM]":"5.4","Tissue RNA - pancreas [nTPM]":"11.2","Tissue RNA - parathyroid gland [nTPM]":"25.3","Tissue RNA - pituitary gland [nTPM]":"9.8","Tissue RNA - placenta [nTPM]":"15.1","Tissue RNA - pons [nTPM]":"3.8","Tissue RNA - prostate [nTPM]":"12.6","Tissue RNA - rectum [nTPM]":"7.0","Tissue RNA - retina [nTPM]":"4.6","Tissue RNA - salivary gland [nTPM]":"11.7","Tissue RNA - seminal vesicle [nTPM]":"10.3","Tissue RNA - skeletal muscle [nTPM]":"2.0","Tissue RNA - skin 1 [nTPM]":"24.0","Tissue RNA - small intestine [nTPM]":"4.6","Tissue RNA - smooth muscle [nTPM]":"9.3","Tissue RNA - spinal cord [nTPM]":"3.0","Tissue RNA - spleen [nTPM]":"4.0","Tissue RNA - stomach 1 [nTPM]":"7.4","Tissue RNA - testis [nTPM]":"3.6","Tissue RNA - thalamus [nTPM]":"3.3","Tissue RNA - thymus [nTPM]":"10.0","Tissue RNA - thyroid gland [nTPM]":"22.3","Tissue RNA - tongue [nTPM]":"5.6","Tissue RNA - tonsil [nTPM]":"9.9","Tissue RNA - urinary bladder [nTPM]":"21.6","Tissue RNA - vagina [nTPM]":"10.2","Tissue RNA - white matter [nTPM]":"3.2","Cell RNA - A-431 [nTPM]":"59.8","Cell RNA - A549 [nTPM]":"11.0","Cell RNA - AF22 [nTPM]":"29.6","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"7.9","Cell RNA - ASC TERT1 [nTPM]":"20.6","Cell RNA - BEWO [nTPM]":"17.1","Cell RNA - BJ [nTPM]":"31.0","Cell RNA - BJ hTERT+ [nTPM]":"34.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"27.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.6","Cell RNA - CACO-2 [nTPM]":"6.2","Cell RNA - CAPAN-2 [nTPM]":"47.8","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"51.4","Cell RNA - fHDF\/TERT166 [nTPM]":"29.7","Cell RNA - GAMG [nTPM]":"9.1","Cell RNA - HaCaT [nTPM]":"90.3","Cell RNA - HAP1 [nTPM]":"16.8","Cell RNA - HBEC3-KT [nTPM]":"65.7","Cell RNA - HBF TERT88 [nTPM]":"51.0","Cell RNA - HDLM-2 [nTPM]":"13.5","Cell RNA - HEK 293 [nTPM]":"18.0","Cell RNA - HEL [nTPM]":"31.4","Cell RNA - HeLa [nTPM]":"12.2","Cell RNA - Hep G2 [nTPM]":"8.5","Cell RNA - HHSteC [nTPM]":"93.4","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"23.0","Cell RNA - hTCEpi [nTPM]":"127.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"29.4","Cell RNA - hTERT-HME1 [nTPM]":"91.5","Cell RNA - hTERT-RPE1 [nTPM]":"67.1","Cell RNA - HUVEC TERT2 [nTPM]":"58.2","Cell RNA - JURKAT [nTPM]":"7.0","Cell RNA - K-562 [nTPM]":"3.2","Cell RNA - Karpas-707 [nTPM]":"27.0","Cell RNA - LHCN-M2 [nTPM]":"31.5","Cell RNA - MCF7 [nTPM]":"25.5","Cell RNA - MOLT-4 [nTPM]":"29.8","Cell RNA - NB-4 [nTPM]":"2.7","Cell RNA - NTERA-2 [nTPM]":"6.7","Cell RNA - OE19 [nTPM]":"4.7","Cell RNA - PC-3 [nTPM]":"20.6","Cell RNA - REH [nTPM]":"2.3","Cell RNA - RH-30 [nTPM]":"12.3","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"59.1","Cell RNA - RT4 [nTPM]":"39.5","Cell RNA - SCLC-21H [nTPM]":"10.0","Cell RNA - SH-SY5Y [nTPM]":"7.9","Cell RNA - SiHa [nTPM]":"44.8","Cell RNA - SK-BR-3 [nTPM]":"22.8","Cell RNA - SK-MEL-30 [nTPM]":"59.9","Cell RNA - SuSa [nTPM]":"15.8","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"11.6","Cell RNA - TIME [nTPM]":"4.1","Cell RNA - U-138 MG [nTPM]":"6.1","Cell RNA - U-2 OS [nTPM]":"32.0","Cell RNA - U-2197 [nTPM]":"24.9","Cell RNA - U-251 MG [nTPM]":"32.7","Cell RNA - U-266\/70 [nTPM]":"6.4","Cell RNA - U-266\/84 [nTPM]":"3.7","Cell RNA - U-698 [nTPM]":"13.3","Cell RNA - U-87 MG [nTPM]":"18.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"40.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.9","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"4.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"3.0","Brain RNA - basal ganglia [nTPM]":"2.8","Brain RNA - cerebellum [nTPM]":"3.1","Brain RNA - cerebral cortex [nTPM]":"4.3","Brain RNA - hippocampal formation [nTPM]":"2.9","Brain RNA - hypothalamus [nTPM]":"3.0","Brain RNA - medulla oblongata [nTPM]":"3.8","Brain RNA - midbrain [nTPM]":"3.1","Brain RNA - pons [nTPM]":"3.8","Brain RNA - spinal cord [nTPM]":"3.0","Brain RNA - thalamus [nTPM]":"3.3","Brain RNA - white matter [nTPM]":"3.2","Single Cell Type RNA - Adipocytes [nTPM]":"38.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"22.5","Single Cell Type RNA - Astrocytes [nTPM]":"10.1","Single Cell Type RNA - B-cells [nTPM]":"2.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"46.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"51.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"42.7","Single Cell Type RNA - Bipolar cells [nTPM]":"4.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"35.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"22.7","Single Cell Type RNA - dendritic cells [nTPM]":"2.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"11.7","Single Cell Type RNA - Early spermatids [nTPM]":"9.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"51.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.8","Single Cell Type RNA - Endothelial cells [nTPM]":"42.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.3","Single Cell Type RNA - Erythroid cells [nTPM]":"6.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.1","Single Cell Type RNA - Fibroblasts [nTPM]":"7.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"73.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"11.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.9","Single Cell Type RNA - Hepatocytes [nTPM]":"3.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.4","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.4","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"5.1","Single Cell Type RNA - Late spermatids [nTPM]":"2.9","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"1.3","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"11.8","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.5","Single Cell Type RNA - Paneth cells [nTPM]":"3.2","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"8.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"53.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.7","Single Cell Type RNA - Spermatocytes [nTPM]":"7.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"41.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"44.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.6","Single Cell Type RNA - T-cells [nTPM]":"3.0","Single Cell Type RNA - Theca cells [nTPM]":"1.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.6","Single Cell Type RNA - Urothelial cells [nTPM]":"23.2"},{"Gene":"G6PC","Gene synonym":["G6PC1","G6PT","GSD1a"],"Ensembl":"ENSG00000131482","Gene description":"Glucose-6-phosphatase catalytic subunit","Uniprot":["P35575"],"Chromosome":"17","Position":"42900797-42914438","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Gluconeogenesis"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Glycogen storage disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"kidney":"75.1","liver":"286.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hepatocytes":"246.2","Proximal enterocytes":"176.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"72","RNA cancer specific FPKM":{"liver cancer":"151.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052324"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052324":"AB_2681790"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.42e-5"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.79e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.4","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"19.7","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"4.1","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"75.1","Tissue RNA - liver [nTPM]":"286.7","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"30.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.4","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"28.6","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"246.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.5","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"3.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"176.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"43.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.7","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"G6PC3","Gene synonym":["UGRP"],"Ensembl":"ENSG00000141349","Gene description":"Glucose-6-phosphatase catalytic subunit 3","Uniprot":["Q9BUM1"],"Chromosome":"17","Position":"44070735-44076344","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Gluconeogenesis"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067052"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA067052":"AB_2685771"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.11e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.61e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-2"},"Tissue RNA - adipose tissue [nTPM]":"56.7","Tissue RNA - adrenal gland [nTPM]":"97.2","Tissue RNA - amygdala [nTPM]":"64.8","Tissue RNA - appendix [nTPM]":"22.5","Tissue RNA - basal ganglia [nTPM]":"67.8","Tissue RNA - bone marrow [nTPM]":"16.0","Tissue RNA - breast [nTPM]":"55.6","Tissue RNA - cerebellum [nTPM]":"70.5","Tissue RNA - cerebral cortex [nTPM]":"79.3","Tissue RNA - cervix [nTPM]":"47.6","Tissue RNA - choroid plexus [nTPM]":"88.8","Tissue RNA - colon [nTPM]":"42.1","Tissue RNA - duodenum [nTPM]":"28.7","Tissue RNA - endometrium 1 [nTPM]":"55.4","Tissue RNA - epididymis [nTPM]":"63.9","Tissue RNA - esophagus [nTPM]":"37.1","Tissue RNA - fallopian tube [nTPM]":"45.6","Tissue RNA - gallbladder [nTPM]":"23.9","Tissue RNA - heart muscle [nTPM]":"61.9","Tissue RNA - hippocampal formation [nTPM]":"65.3","Tissue RNA - hypothalamus [nTPM]":"77.5","Tissue RNA - kidney [nTPM]":"75.2","Tissue RNA - liver [nTPM]":"26.4","Tissue RNA - lung [nTPM]":"42.9","Tissue RNA - lymph node [nTPM]":"19.3","Tissue RNA - medulla oblongata [nTPM]":"74.9","Tissue RNA - midbrain [nTPM]":"86.9","Tissue RNA - ovary [nTPM]":"44.3","Tissue RNA - pancreas [nTPM]":"56.5","Tissue RNA - parathyroid gland [nTPM]":"66.7","Tissue RNA - pituitary gland [nTPM]":"95.1","Tissue RNA - placenta [nTPM]":"25.8","Tissue RNA - pons [nTPM]":"96.1","Tissue RNA - prostate [nTPM]":"59.5","Tissue RNA - rectum [nTPM]":"18.2","Tissue RNA - retina [nTPM]":"17.1","Tissue RNA - salivary gland [nTPM]":"48.7","Tissue RNA - seminal vesicle [nTPM]":"40.6","Tissue RNA - skeletal muscle [nTPM]":"54.3","Tissue RNA - skin 1 [nTPM]":"26.8","Tissue RNA - small intestine [nTPM]":"39.6","Tissue RNA - smooth muscle [nTPM]":"23.0","Tissue RNA - spinal cord [nTPM]":"67.9","Tissue RNA - spleen [nTPM]":"45.2","Tissue RNA - stomach 1 [nTPM]":"51.4","Tissue RNA - testis [nTPM]":"55.1","Tissue RNA - thalamus [nTPM]":"72.7","Tissue RNA - thymus [nTPM]":"15.2","Tissue RNA - thyroid gland [nTPM]":"71.1","Tissue RNA - tongue [nTPM]":"26.4","Tissue RNA - tonsil [nTPM]":"12.0","Tissue RNA - urinary bladder [nTPM]":"48.7","Tissue RNA - vagina [nTPM]":"37.7","Tissue RNA - white matter [nTPM]":"72.4","Cell RNA - A-431 [nTPM]":"40.0","Cell RNA - A549 [nTPM]":"231.7","Cell RNA - AF22 [nTPM]":"73.7","Cell RNA - AN3-CA [nTPM]":"128.5","Cell RNA - ASC diff [nTPM]":"77.9","Cell RNA - ASC TERT1 [nTPM]":"58.3","Cell RNA - BEWO [nTPM]":"55.3","Cell RNA - BJ [nTPM]":"45.0","Cell RNA - BJ hTERT+ [nTPM]":"86.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"96.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"64.4","Cell RNA - CACO-2 [nTPM]":"97.1","Cell RNA - CAPAN-2 [nTPM]":"62.3","Cell RNA - Daudi [nTPM]":"88.9","Cell RNA - EFO-21 [nTPM]":"62.8","Cell RNA - fHDF\/TERT166 [nTPM]":"95.1","Cell RNA - GAMG [nTPM]":"65.4","Cell RNA - HaCaT [nTPM]":"67.4","Cell RNA - HAP1 [nTPM]":"53.5","Cell RNA - HBEC3-KT [nTPM]":"92.1","Cell RNA - HBF TERT88 [nTPM]":"44.5","Cell RNA - HDLM-2 [nTPM]":"46.4","Cell RNA - HEK 293 [nTPM]":"86.0","Cell RNA - HEL [nTPM]":"49.3","Cell RNA - HeLa [nTPM]":"142.5","Cell RNA - Hep G2 [nTPM]":"182.4","Cell RNA - HHSteC [nTPM]":"84.1","Cell RNA - HL-60 [nTPM]":"46.1","Cell RNA - HMC-1 [nTPM]":"59.8","Cell RNA - HSkMC [nTPM]":"77.3","Cell RNA - hTCEpi [nTPM]":"44.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"93.1","Cell RNA - hTERT-HME1 [nTPM]":"62.3","Cell RNA - hTERT-RPE1 [nTPM]":"59.6","Cell RNA - HUVEC TERT2 [nTPM]":"79.3","Cell RNA - JURKAT [nTPM]":"35.9","Cell RNA - K-562 [nTPM]":"51.5","Cell RNA - Karpas-707 [nTPM]":"109.6","Cell RNA - LHCN-M2 [nTPM]":"72.5","Cell RNA - MCF7 [nTPM]":"112.1","Cell RNA - MOLT-4 [nTPM]":"22.4","Cell RNA - NB-4 [nTPM]":"71.4","Cell RNA - NTERA-2 [nTPM]":"99.3","Cell RNA - OE19 [nTPM]":"48.7","Cell RNA - PC-3 [nTPM]":"133.5","Cell RNA - REH [nTPM]":"45.6","Cell RNA - RH-30 [nTPM]":"48.4","Cell RNA - RPMI-8226 [nTPM]":"207.5","Cell RNA - RPTEC TERT1 [nTPM]":"137.6","Cell RNA - RT4 [nTPM]":"93.6","Cell RNA - SCLC-21H [nTPM]":"92.7","Cell RNA - SH-SY5Y [nTPM]":"83.0","Cell RNA - SiHa [nTPM]":"49.1","Cell RNA - SK-BR-3 [nTPM]":"57.4","Cell RNA - SK-MEL-30 [nTPM]":"59.3","Cell RNA - SuSa [nTPM]":"82.9","Cell RNA - T-47d [nTPM]":"158.6","Cell RNA - THP-1 [nTPM]":"45.1","Cell RNA - TIME [nTPM]":"87.6","Cell RNA - U-138 MG [nTPM]":"98.8","Cell RNA - U-2 OS [nTPM]":"53.1","Cell RNA - U-2197 [nTPM]":"26.8","Cell RNA - U-251 MG [nTPM]":"63.5","Cell RNA - U-266\/70 [nTPM]":"74.0","Cell RNA - U-266\/84 [nTPM]":"56.2","Cell RNA - U-698 [nTPM]":"26.1","Cell RNA - U-87 MG [nTPM]":"110.3","Cell RNA - U-937 [nTPM]":"38.2","Cell RNA - WM-115 [nTPM]":"128.9","Blood RNA - basophil [nTPM]":"3.0","Blood RNA - classical monocyte [nTPM]":"33.1","Blood RNA - eosinophil [nTPM]":"7.9","Blood RNA - gdT-cell [nTPM]":"9.9","Blood RNA - intermediate monocyte [nTPM]":"43.4","Blood RNA - MAIT T-cell [nTPM]":"12.1","Blood RNA - memory B-cell [nTPM]":"12.1","Blood RNA - memory CD4 T-cell [nTPM]":"8.0","Blood RNA - memory CD8 T-cell [nTPM]":"9.1","Blood RNA - myeloid DC [nTPM]":"54.2","Blood RNA - naive B-cell [nTPM]":"13.9","Blood RNA - naive CD4 T-cell [nTPM]":"9.7","Blood RNA - naive CD8 T-cell [nTPM]":"12.9","Blood RNA - neutrophil [nTPM]":"1.4","Blood RNA - NK-cell [nTPM]":"17.5","Blood RNA - non-classical monocyte [nTPM]":"26.3","Blood RNA - plasmacytoid DC [nTPM]":"74.5","Blood RNA - T-reg [nTPM]":"8.5","Blood RNA - total PBMC [nTPM]":"16.9","Brain RNA - amygdala [nTPM]":"64.8","Brain RNA - basal ganglia [nTPM]":"67.8","Brain RNA - cerebellum [nTPM]":"70.5","Brain RNA - cerebral cortex [nTPM]":"79.3","Brain RNA - hippocampal formation [nTPM]":"65.3","Brain RNA - hypothalamus [nTPM]":"77.5","Brain RNA - medulla oblongata [nTPM]":"74.9","Brain RNA - midbrain [nTPM]":"86.9","Brain RNA - pons [nTPM]":"96.1","Brain RNA - spinal cord [nTPM]":"67.9","Brain RNA - thalamus [nTPM]":"72.7","Brain RNA - white matter [nTPM]":"72.4","Single Cell Type RNA - Adipocytes [nTPM]":"22.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.9","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"10.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"31.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"10.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"20.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"25.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"64.3","Single Cell Type RNA - dendritic cells [nTPM]":"17.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"59.3","Single Cell Type RNA - Early spermatids [nTPM]":"5.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.1","Single Cell Type RNA - Endothelial cells [nTPM]":"26.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.9","Single Cell Type RNA - Erythroid cells [nTPM]":"9.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"49.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"41.1","Single Cell Type RNA - Fibroblasts [nTPM]":"25.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.1","Single Cell Type RNA - granulocytes [nTPM]":"18.3","Single Cell Type RNA - Granulosa cells [nTPM]":"20.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.5","Single Cell Type RNA - Hepatocytes [nTPM]":"7.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"58.7","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.1","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"21.6","Single Cell Type RNA - Langerhans cells [nTPM]":"12.2","Single Cell Type RNA - Late spermatids [nTPM]":"6.2","Single Cell Type RNA - Leydig cells [nTPM]":"20.2","Single Cell Type RNA - Macrophages [nTPM]":"20.9","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"21.8","Single Cell Type RNA - Muller glia cells [nTPM]":"30.7","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"33.6","Single Cell Type RNA - Paneth cells [nTPM]":"13.6","Single Cell Type RNA - Peritubular cells [nTPM]":"23.0","Single Cell Type RNA - Plasma cells [nTPM]":"27.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"36.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"24.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.3","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.4","Single Cell Type RNA - Spermatocytes [nTPM]":"31.5","Single Cell Type RNA - Spermatogonia [nTPM]":"26.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"42.5","Single Cell Type RNA - T-cells [nTPM]":"7.0","Single Cell Type RNA - Theca cells [nTPM]":"43.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.7","Single Cell Type RNA - Urothelial cells [nTPM]":"17.2"},{"Gene":"G6PD","Gene synonym":["G6PD1"],"Ensembl":"ENSG00000160211","Gene description":"Glucose-6-phosphate dehydrogenase","Uniprot":["P11413"],"Chromosome":"X","Position":"154531391-154547572","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism","Glucose metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Cancer-related genes","Disease variant","Hereditary hemolytic anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"105.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"monocytes":"112.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"412.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"412.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"2333.8","MCF7":"883.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000247","HPA000834"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2400000","Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 3: Monocytes - Immune response regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":["Centriolar satellite"],"Antibody RRID":{"HPA000247":"AB_1078978","HPA000834":"AB_1078977"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.45e-13"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"},"Tissue RNA - adipose tissue [nTPM]":"40.7","Tissue RNA - adrenal gland [nTPM]":"39.1","Tissue RNA - amygdala [nTPM]":"19.9","Tissue RNA - appendix [nTPM]":"30.2","Tissue RNA - basal ganglia [nTPM]":"21.8","Tissue RNA - bone marrow [nTPM]":"105.9","Tissue RNA - breast [nTPM]":"31.9","Tissue RNA - cerebellum [nTPM]":"20.5","Tissue RNA - cerebral cortex [nTPM]":"28.3","Tissue RNA - cervix [nTPM]":"20.6","Tissue RNA - choroid plexus [nTPM]":"20.0","Tissue RNA - colon [nTPM]":"13.9","Tissue RNA - duodenum [nTPM]":"13.1","Tissue RNA - endometrium 1 [nTPM]":"21.6","Tissue RNA - epididymis [nTPM]":"13.3","Tissue RNA - esophagus [nTPM]":"54.3","Tissue RNA - fallopian tube [nTPM]":"19.3","Tissue RNA - gallbladder [nTPM]":"46.5","Tissue RNA - heart muscle [nTPM]":"14.3","Tissue RNA - hippocampal formation [nTPM]":"21.3","Tissue RNA - hypothalamus [nTPM]":"22.7","Tissue RNA - kidney [nTPM]":"12.7","Tissue RNA - liver [nTPM]":"6.5","Tissue RNA - lung [nTPM]":"29.4","Tissue RNA - lymph node [nTPM]":"28.9","Tissue RNA - medulla oblongata [nTPM]":"25.4","Tissue RNA - midbrain [nTPM]":"22.2","Tissue RNA - ovary [nTPM]":"24.1","Tissue RNA - pancreas [nTPM]":"13.0","Tissue RNA - parathyroid gland [nTPM]":"9.6","Tissue RNA - pituitary gland [nTPM]":"27.5","Tissue RNA - placenta [nTPM]":"13.7","Tissue RNA - pons [nTPM]":"24.5","Tissue RNA - prostate [nTPM]":"12.2","Tissue RNA - rectum [nTPM]":"13.1","Tissue RNA - retina [nTPM]":"26.1","Tissue RNA - salivary gland [nTPM]":"21.2","Tissue RNA - seminal vesicle [nTPM]":"14.4","Tissue RNA - skeletal muscle [nTPM]":"4.2","Tissue RNA - skin 1 [nTPM]":"21.3","Tissue RNA - small intestine [nTPM]":"12.4","Tissue RNA - smooth muscle [nTPM]":"25.6","Tissue RNA - spinal cord [nTPM]":"19.7","Tissue RNA - spleen [nTPM]":"26.9","Tissue RNA - stomach 1 [nTPM]":"18.1","Tissue RNA - testis [nTPM]":"54.0","Tissue RNA - thalamus [nTPM]":"26.1","Tissue RNA - thymus [nTPM]":"26.2","Tissue RNA - thyroid gland [nTPM]":"45.9","Tissue RNA - tongue [nTPM]":"5.1","Tissue RNA - tonsil [nTPM]":"37.2","Tissue RNA - urinary bladder [nTPM]":"33.8","Tissue RNA - vagina [nTPM]":"22.4","Tissue RNA - white matter [nTPM]":"21.9","Cell RNA - A-431 [nTPM]":"168.5","Cell RNA - A549 [nTPM]":"2333.8","Cell RNA - AF22 [nTPM]":"49.7","Cell RNA - AN3-CA [nTPM]":"189.7","Cell RNA - ASC diff [nTPM]":"207.2","Cell RNA - ASC TERT1 [nTPM]":"281.7","Cell RNA - BEWO [nTPM]":"43.5","Cell RNA - BJ [nTPM]":"116.0","Cell RNA - BJ hTERT+ [nTPM]":"341.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"120.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"205.8","Cell RNA - CACO-2 [nTPM]":"111.2","Cell RNA - CAPAN-2 [nTPM]":"61.9","Cell RNA - Daudi [nTPM]":"110.9","Cell RNA - EFO-21 [nTPM]":"174.1","Cell RNA - fHDF\/TERT166 [nTPM]":"274.3","Cell RNA - GAMG [nTPM]":"475.9","Cell RNA - HaCaT [nTPM]":"146.3","Cell RNA - HAP1 [nTPM]":"79.3","Cell RNA - HBEC3-KT [nTPM]":"202.5","Cell RNA - HBF TERT88 [nTPM]":"60.3","Cell RNA - HDLM-2 [nTPM]":"111.4","Cell RNA - HEK 293 [nTPM]":"55.0","Cell RNA - HEL [nTPM]":"116.8","Cell RNA - HeLa [nTPM]":"517.2","Cell RNA - Hep G2 [nTPM]":"244.6","Cell RNA - HHSteC [nTPM]":"401.6","Cell RNA - HL-60 [nTPM]":"117.8","Cell RNA - HMC-1 [nTPM]":"373.5","Cell RNA - HSkMC [nTPM]":"136.6","Cell RNA - hTCEpi [nTPM]":"58.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"233.9","Cell RNA - hTERT-HME1 [nTPM]":"49.8","Cell RNA - hTERT-RPE1 [nTPM]":"185.6","Cell RNA - HUVEC TERT2 [nTPM]":"252.5","Cell RNA - JURKAT [nTPM]":"79.8","Cell RNA - K-562 [nTPM]":"69.6","Cell RNA - Karpas-707 [nTPM]":"46.3","Cell RNA - LHCN-M2 [nTPM]":"218.4","Cell RNA - MCF7 [nTPM]":"883.9","Cell RNA - MOLT-4 [nTPM]":"77.5","Cell RNA - NB-4 [nTPM]":"93.0","Cell RNA - NTERA-2 [nTPM]":"35.3","Cell RNA - OE19 [nTPM]":"549.5","Cell RNA - PC-3 [nTPM]":"172.2","Cell RNA - REH [nTPM]":"74.9","Cell RNA - RH-30 [nTPM]":"28.4","Cell RNA - RPMI-8226 [nTPM]":"120.5","Cell RNA - RPTEC TERT1 [nTPM]":"357.1","Cell RNA - RT4 [nTPM]":"210.9","Cell RNA - SCLC-21H [nTPM]":"49.6","Cell RNA - SH-SY5Y [nTPM]":"62.0","Cell RNA - SiHa [nTPM]":"115.9","Cell RNA - SK-BR-3 [nTPM]":"444.5","Cell RNA - SK-MEL-30 [nTPM]":"99.9","Cell RNA - SuSa [nTPM]":"65.0","Cell RNA - T-47d [nTPM]":"67.1","Cell RNA - THP-1 [nTPM]":"99.4","Cell RNA - TIME [nTPM]":"289.8","Cell RNA - U-138 MG [nTPM]":"73.1","Cell RNA - U-2 OS [nTPM]":"250.0","Cell RNA - U-2197 [nTPM]":"102.5","Cell RNA - U-251 MG [nTPM]":"181.8","Cell RNA - U-266\/70 [nTPM]":"58.2","Cell RNA - U-266\/84 [nTPM]":"80.0","Cell RNA - U-698 [nTPM]":"189.8","Cell RNA - U-87 MG [nTPM]":"200.6","Cell RNA - U-937 [nTPM]":"77.5","Cell RNA - WM-115 [nTPM]":"150.9","Blood RNA - basophil [nTPM]":"166.1","Blood RNA - classical monocyte [nTPM]":"84.9","Blood RNA - eosinophil [nTPM]":"412.7","Blood RNA - gdT-cell [nTPM]":"50.3","Blood RNA - intermediate monocyte [nTPM]":"72.1","Blood RNA - MAIT T-cell [nTPM]":"32.1","Blood RNA - memory B-cell [nTPM]":"16.0","Blood RNA - memory CD4 T-cell [nTPM]":"13.7","Blood RNA - memory CD8 T-cell [nTPM]":"36.7","Blood RNA - myeloid DC [nTPM]":"40.1","Blood RNA - naive B-cell [nTPM]":"17.0","Blood RNA - naive CD4 T-cell [nTPM]":"16.5","Blood RNA - naive CD8 T-cell [nTPM]":"28.2","Blood RNA - neutrophil [nTPM]":"137.4","Blood RNA - NK-cell [nTPM]":"69.3","Blood RNA - non-classical monocyte [nTPM]":"63.5","Blood RNA - plasmacytoid DC [nTPM]":"18.9","Blood RNA - T-reg [nTPM]":"18.7","Blood RNA - total PBMC [nTPM]":"72.8","Brain RNA - amygdala [nTPM]":"19.9","Brain RNA - basal ganglia [nTPM]":"21.8","Brain RNA - cerebellum [nTPM]":"20.5","Brain RNA - cerebral cortex [nTPM]":"28.3","Brain RNA - hippocampal formation [nTPM]":"21.3","Brain RNA - hypothalamus [nTPM]":"22.7","Brain RNA - medulla oblongata [nTPM]":"25.4","Brain RNA - midbrain [nTPM]":"22.2","Brain RNA - pons [nTPM]":"24.5","Brain RNA - spinal cord [nTPM]":"19.7","Brain RNA - thalamus [nTPM]":"26.1","Brain RNA - white matter [nTPM]":"21.9","Single Cell Type RNA - Adipocytes [nTPM]":"7.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.0","Single Cell Type RNA - Astrocytes [nTPM]":"4.6","Single Cell Type RNA - B-cells [nTPM]":"21.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"46.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"6.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"22.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"29.6","Single Cell Type RNA - dendritic cells [nTPM]":"58.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"25.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"29.4","Single Cell Type RNA - Ductal cells [nTPM]":"39.3","Single Cell Type RNA - Early spermatids [nTPM]":"10.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.7","Single Cell Type RNA - Endothelial cells [nTPM]":"13.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.5","Single Cell Type RNA - Erythroid cells [nTPM]":"37.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"29.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"41.2","Single Cell Type RNA - Fibroblasts [nTPM]":"19.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.7","Single Cell Type RNA - granulocytes [nTPM]":"37.5","Single Cell Type RNA - Granulosa cells [nTPM]":"26.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.2","Single Cell Type RNA - Hepatocytes [nTPM]":"1.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"45.6","Single Cell Type RNA - Horizontal cells [nTPM]":"33.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.5","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"58.2","Single Cell Type RNA - Langerhans cells [nTPM]":"26.0","Single Cell Type RNA - Late spermatids [nTPM]":"20.8","Single Cell Type RNA - Leydig cells [nTPM]":"26.1","Single Cell Type RNA - Macrophages [nTPM]":"56.6","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"112.3","Single Cell Type RNA - Muller glia cells [nTPM]":"13.6","Single Cell Type RNA - NK-cells [nTPM]":"83.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"31.0","Single Cell Type RNA - Paneth cells [nTPM]":"11.4","Single Cell Type RNA - Peritubular cells [nTPM]":"16.1","Single Cell Type RNA - Plasma cells [nTPM]":"21.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"32.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.6","Single Cell Type RNA - Spermatocytes [nTPM]":"10.9","Single Cell Type RNA - Spermatogonia [nTPM]":"32.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"34.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"36.3","Single Cell Type RNA - T-cells [nTPM]":"33.8","Single Cell Type RNA - Theca cells [nTPM]":"11.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.5","Single Cell Type RNA - Urothelial cells [nTPM]":"30.5"},{"Gene":"GAD1","Gene synonym":["GAD"],"Ensembl":"ENSG00000128683","Gene description":"Glutamate decarboxylase 1","Uniprot":["Q99259"],"Chromosome":"2","Position":"170813213-170861151","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Neurotransmitter biosynthesis"],"Molecular function":["Decarboxylase","Lyase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"brain":"98.5","parathyroid gland":"46.3","retina":"29.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Inhibitory neurons":"392.8","Oligodendrocyte precursor cells":"146.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"4.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"20.1","HEL":"64.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"olfactory bulb":"547.6"},"Antibody":["CAB004415","HPA048871","HPA058412","CAB078176"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Vesicles","Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB004415":"AB_627650","CAB078176":"AB_2665792","HPA048871":null,"HPA058412":"AB_2683710"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.31e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.61e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.90e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"3.0","Tissue RNA - amygdala [nTPM]":"22.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"29.9","Tissue RNA - bone marrow [nTPM]":"3.3","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"15.5","Tissue RNA - cerebral cortex [nTPM]":"33.0","Tissue RNA - cervix [nTPM]":"1.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"1.6","Tissue RNA - epididymis [nTPM]":"4.3","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"17.1","Tissue RNA - hypothalamus [nTPM]":"98.5","Tissue RNA - kidney [nTPM]":"4.8","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"12.4","Tissue RNA - midbrain [nTPM]":"41.6","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"46.3","Tissue RNA - pituitary gland [nTPM]":"5.0","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"17.6","Tissue RNA - prostate [nTPM]":"0.8","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"29.7","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"12.7","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"3.2","Tissue RNA - thalamus [nTPM]":"31.1","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.6","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"14.2","Cell RNA - A-431 [nTPM]":"18.2","Cell RNA - A549 [nTPM]":"0.7","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"7.3","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.4","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.7","Cell RNA - CACO-2 [nTPM]":"4.6","Cell RNA - CAPAN-2 [nTPM]":"6.7","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.9","Cell RNA - fHDF\/TERT166 [nTPM]":"0.5","Cell RNA - GAMG [nTPM]":"2.9","Cell RNA - HaCaT [nTPM]":"20.1","Cell RNA - HAP1 [nTPM]":"2.3","Cell RNA - HBEC3-KT [nTPM]":"0.6","Cell RNA - HBF TERT88 [nTPM]":"1.6","Cell RNA - HDLM-2 [nTPM]":"2.8","Cell RNA - HEK 293 [nTPM]":"13.4","Cell RNA - HEL [nTPM]":"64.5","Cell RNA - HeLa [nTPM]":"6.0","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"1.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"5.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"2.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"17.0","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.8","Cell RNA - MCF7 [nTPM]":"1.5","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"8.1","Cell RNA - OE19 [nTPM]":"9.7","Cell RNA - PC-3 [nTPM]":"6.7","Cell RNA - REH [nTPM]":"1.0","Cell RNA - RH-30 [nTPM]":"4.6","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"8.5","Cell RNA - RT4 [nTPM]":"9.4","Cell RNA - SCLC-21H [nTPM]":"6.7","Cell RNA - SH-SY5Y [nTPM]":"2.1","Cell RNA - SiHa [nTPM]":"12.6","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"3.5","Cell RNA - SuSa [nTPM]":"0.6","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"12.0","Cell RNA - U-2 OS [nTPM]":"1.7","Cell RNA - U-2197 [nTPM]":"2.4","Cell RNA - U-251 MG [nTPM]":"7.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"11.5","Cell RNA - U-937 [nTPM]":"3.2","Cell RNA - WM-115 [nTPM]":"16.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"22.1","Brain RNA - basal ganglia [nTPM]":"29.9","Brain RNA - cerebellum [nTPM]":"15.5","Brain RNA - cerebral cortex [nTPM]":"33.0","Brain RNA - hippocampal formation [nTPM]":"17.1","Brain RNA - hypothalamus [nTPM]":"98.5","Brain RNA - medulla oblongata [nTPM]":"12.4","Brain RNA - midbrain [nTPM]":"41.6","Brain RNA - pons [nTPM]":"17.6","Brain RNA - spinal cord [nTPM]":"12.7","Brain RNA - thalamus [nTPM]":"31.1","Brain RNA - white matter [nTPM]":"14.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"32.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.5","Single Cell Type RNA - Early spermatids [nTPM]":"5.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"5.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.0","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"392.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"6.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"146.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"4.4","Single Cell Type RNA - Spermatogonia [nTPM]":"7.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"GALC","Gene synonym":[],"Ensembl":"ENSG00000054983","Gene description":"Galactosylceramidase","Uniprot":["P54803"],"Chromosome":"14","Position":"87837820-87993665","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid degradation","Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant","Leukodystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"68.4","Kupffer cells":"72.1","Late spermatids":"77.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"84.3","HMC-1":"78.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022196"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"53000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022196":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.0","Tissue RNA - adrenal gland [nTPM]":"17.2","Tissue RNA - amygdala [nTPM]":"20.0","Tissue RNA - appendix [nTPM]":"14.9","Tissue RNA - basal ganglia [nTPM]":"23.3","Tissue RNA - bone marrow [nTPM]":"23.2","Tissue RNA - breast [nTPM]":"13.3","Tissue RNA - cerebellum [nTPM]":"22.1","Tissue RNA - cerebral cortex [nTPM]":"26.1","Tissue RNA - cervix [nTPM]":"12.0","Tissue RNA - choroid plexus [nTPM]":"20.8","Tissue RNA - colon [nTPM]":"15.1","Tissue RNA - duodenum [nTPM]":"33.3","Tissue RNA - endometrium 1 [nTPM]":"11.1","Tissue RNA - epididymis [nTPM]":"12.2","Tissue RNA - esophagus [nTPM]":"6.6","Tissue RNA - fallopian tube [nTPM]":"20.7","Tissue RNA - gallbladder [nTPM]":"18.4","Tissue RNA - heart muscle [nTPM]":"13.5","Tissue RNA - hippocampal formation [nTPM]":"18.5","Tissue RNA - hypothalamus [nTPM]":"21.6","Tissue RNA - kidney [nTPM]":"21.3","Tissue RNA - liver [nTPM]":"12.1","Tissue RNA - lung [nTPM]":"23.9","Tissue RNA - lymph node [nTPM]":"11.7","Tissue RNA - medulla oblongata [nTPM]":"23.0","Tissue RNA - midbrain [nTPM]":"22.6","Tissue RNA - ovary [nTPM]":"15.8","Tissue RNA - pancreas [nTPM]":"10.8","Tissue RNA - parathyroid gland [nTPM]":"9.4","Tissue RNA - pituitary gland [nTPM]":"9.8","Tissue RNA - placenta [nTPM]":"16.8","Tissue RNA - pons [nTPM]":"23.9","Tissue RNA - prostate [nTPM]":"14.3","Tissue RNA - rectum [nTPM]":"17.3","Tissue RNA - retina [nTPM]":"18.4","Tissue RNA - salivary gland [nTPM]":"8.1","Tissue RNA - seminal vesicle [nTPM]":"9.3","Tissue RNA - skeletal muscle [nTPM]":"8.0","Tissue RNA - skin 1 [nTPM]":"9.1","Tissue RNA - small intestine [nTPM]":"34.4","Tissue RNA - smooth muscle [nTPM]":"9.6","Tissue RNA - spinal cord [nTPM]":"22.3","Tissue RNA - spleen [nTPM]":"15.4","Tissue RNA - stomach 1 [nTPM]":"16.4","Tissue RNA - testis [nTPM]":"24.0","Tissue RNA - thalamus [nTPM]":"20.8","Tissue RNA - thymus [nTPM]":"9.7","Tissue RNA - thyroid gland [nTPM]":"24.5","Tissue RNA - tongue [nTPM]":"12.9","Tissue RNA - tonsil [nTPM]":"7.9","Tissue RNA - urinary bladder [nTPM]":"13.6","Tissue RNA - vagina [nTPM]":"7.5","Tissue RNA - white matter [nTPM]":"30.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"19.5","Cell RNA - AF22 [nTPM]":"7.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"23.8","Cell RNA - ASC TERT1 [nTPM]":"21.3","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"9.1","Cell RNA - BJ hTERT+ [nTPM]":"17.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.9","Cell RNA - CACO-2 [nTPM]":"10.8","Cell RNA - CAPAN-2 [nTPM]":"84.3","Cell RNA - Daudi [nTPM]":"5.3","Cell RNA - EFO-21 [nTPM]":"26.4","Cell RNA - fHDF\/TERT166 [nTPM]":"8.7","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"1.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"1.0","Cell RNA - HBF TERT88 [nTPM]":"10.2","Cell RNA - HDLM-2 [nTPM]":"2.7","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"29.8","Cell RNA - HeLa [nTPM]":"0.7","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"19.5","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"78.4","Cell RNA - HSkMC [nTPM]":"20.7","Cell RNA - hTCEpi [nTPM]":"6.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.6","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"3.4","Cell RNA - HUVEC TERT2 [nTPM]":"22.6","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"10.0","Cell RNA - Karpas-707 [nTPM]":"3.9","Cell RNA - LHCN-M2 [nTPM]":"14.4","Cell RNA - MCF7 [nTPM]":"1.9","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"4.5","Cell RNA - NTERA-2 [nTPM]":"6.5","Cell RNA - OE19 [nTPM]":"35.4","Cell RNA - PC-3 [nTPM]":"2.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.5","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"13.4","Cell RNA - RT4 [nTPM]":"7.8","Cell RNA - SCLC-21H [nTPM]":"6.7","Cell RNA - SH-SY5Y [nTPM]":"15.6","Cell RNA - SiHa [nTPM]":"24.6","Cell RNA - SK-BR-3 [nTPM]":"4.0","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"17.2","Cell RNA - T-47d [nTPM]":"20.4","Cell RNA - THP-1 [nTPM]":"20.5","Cell RNA - TIME [nTPM]":"19.7","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"12.9","Cell RNA - U-2197 [nTPM]":"5.6","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"4.2","Cell RNA - U-266\/84 [nTPM]":"8.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"2.3","Cell RNA - U-937 [nTPM]":"6.8","Cell RNA - WM-115 [nTPM]":"19.2","Blood RNA - basophil [nTPM]":"25.3","Blood RNA - classical monocyte [nTPM]":"15.2","Blood RNA - eosinophil [nTPM]":"34.2","Blood RNA - gdT-cell [nTPM]":"11.1","Blood RNA - intermediate monocyte [nTPM]":"16.6","Blood RNA - MAIT T-cell [nTPM]":"24.0","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"8.3","Blood RNA - memory CD8 T-cell [nTPM]":"10.8","Blood RNA - myeloid DC [nTPM]":"8.9","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"6.0","Blood RNA - naive CD8 T-cell [nTPM]":"7.0","Blood RNA - neutrophil [nTPM]":"11.9","Blood RNA - NK-cell [nTPM]":"16.3","Blood RNA - non-classical monocyte [nTPM]":"13.4","Blood RNA - plasmacytoid DC [nTPM]":"1.6","Blood RNA - T-reg [nTPM]":"5.3","Blood RNA - total PBMC [nTPM]":"11.7","Brain RNA - amygdala [nTPM]":"20.0","Brain RNA - basal ganglia [nTPM]":"23.3","Brain RNA - cerebellum [nTPM]":"22.1","Brain RNA - cerebral cortex [nTPM]":"26.1","Brain RNA - hippocampal formation [nTPM]":"18.5","Brain RNA - hypothalamus [nTPM]":"21.6","Brain RNA - medulla oblongata [nTPM]":"23.0","Brain RNA - midbrain [nTPM]":"22.6","Brain RNA - pons [nTPM]":"23.9","Brain RNA - spinal cord [nTPM]":"22.3","Brain RNA - thalamus [nTPM]":"20.8","Brain RNA - white matter [nTPM]":"30.6","Single Cell Type RNA - Adipocytes [nTPM]":"11.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.0","Single Cell Type RNA - Astrocytes [nTPM]":"26.8","Single Cell Type RNA - B-cells [nTPM]":"8.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"10.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"8.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.2","Single Cell Type RNA - dendritic cells [nTPM]":"27.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.8","Single Cell Type RNA - Early spermatids [nTPM]":"51.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.9","Single Cell Type RNA - Endothelial cells [nTPM]":"11.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.1","Single Cell Type RNA - Erythroid cells [nTPM]":"13.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.7","Single Cell Type RNA - Fibroblasts [nTPM]":"15.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.8","Single Cell Type RNA - granulocytes [nTPM]":"68.4","Single Cell Type RNA - Granulosa cells [nTPM]":"15.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.2","Single Cell Type RNA - Hepatocytes [nTPM]":"6.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"26.6","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.2","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"72.1","Single Cell Type RNA - Langerhans cells [nTPM]":"11.8","Single Cell Type RNA - Late spermatids [nTPM]":"77.9","Single Cell Type RNA - Leydig cells [nTPM]":"16.1","Single Cell Type RNA - Macrophages [nTPM]":"25.0","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"26.7","Single Cell Type RNA - Muller glia cells [nTPM]":"7.3","Single Cell Type RNA - NK-cells [nTPM]":"40.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"33.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"42.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.1","Single Cell Type RNA - Paneth cells [nTPM]":"20.0","Single Cell Type RNA - Peritubular cells [nTPM]":"10.1","Single Cell Type RNA - Plasma cells [nTPM]":"9.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.6","Single Cell Type RNA - Spermatocytes [nTPM]":"14.9","Single Cell Type RNA - Spermatogonia [nTPM]":"10.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.6","Single Cell Type RNA - T-cells [nTPM]":"21.2","Single Cell Type RNA - Theca cells [nTPM]":"12.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.7","Single Cell Type RNA - Urothelial cells [nTPM]":"7.9"},{"Gene":"GALE","Gene synonym":["SDR1E1"],"Ensembl":"ENSG00000117308","Gene description":"UDP-galactose-4-epimerase","Uniprot":["Q14376"],"Chromosome":"1","Position":"23795599-23800781","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism","Galactose metabolism"],"Molecular function":["Isomerase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"stomach 1":"122.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"276.8","Intestinal goblet cells":"149.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070023"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"16000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Golgi apparatus","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA070023":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.68e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.9","Tissue RNA - adrenal gland [nTPM]":"12.8","Tissue RNA - amygdala [nTPM]":"12.3","Tissue RNA - appendix [nTPM]":"16.0","Tissue RNA - basal ganglia [nTPM]":"12.5","Tissue RNA - bone marrow [nTPM]":"6.0","Tissue RNA - breast [nTPM]":"12.8","Tissue RNA - cerebellum [nTPM]":"12.2","Tissue RNA - cerebral cortex [nTPM]":"17.7","Tissue RNA - cervix [nTPM]":"22.3","Tissue RNA - choroid plexus [nTPM]":"11.5","Tissue RNA - colon [nTPM]":"58.6","Tissue RNA - duodenum [nTPM]":"54.6","Tissue RNA - endometrium 1 [nTPM]":"6.7","Tissue RNA - epididymis [nTPM]":"12.7","Tissue RNA - esophagus [nTPM]":"63.1","Tissue RNA - fallopian tube [nTPM]":"16.6","Tissue RNA - gallbladder [nTPM]":"31.5","Tissue RNA - heart muscle [nTPM]":"7.1","Tissue RNA - hippocampal formation [nTPM]":"12.5","Tissue RNA - hypothalamus [nTPM]":"12.5","Tissue RNA - kidney [nTPM]":"34.0","Tissue RNA - liver [nTPM]":"61.2","Tissue RNA - lung [nTPM]":"20.6","Tissue RNA - lymph node [nTPM]":"7.5","Tissue RNA - medulla oblongata [nTPM]":"12.5","Tissue RNA - midbrain [nTPM]":"12.3","Tissue RNA - ovary [nTPM]":"4.6","Tissue RNA - pancreas [nTPM]":"15.2","Tissue RNA - parathyroid gland [nTPM]":"15.5","Tissue RNA - pituitary gland [nTPM]":"6.7","Tissue RNA - placenta [nTPM]":"17.8","Tissue RNA - pons [nTPM]":"12.4","Tissue RNA - prostate [nTPM]":"11.0","Tissue RNA - rectum [nTPM]":"60.0","Tissue RNA - retina [nTPM]":"6.3","Tissue RNA - salivary gland [nTPM]":"59.7","Tissue RNA - seminal vesicle [nTPM]":"16.4","Tissue RNA - skeletal muscle [nTPM]":"4.3","Tissue RNA - skin 1 [nTPM]":"9.7","Tissue RNA - small intestine [nTPM]":"38.3","Tissue RNA - smooth muscle [nTPM]":"10.8","Tissue RNA - spinal cord [nTPM]":"12.6","Tissue RNA - spleen [nTPM]":"17.6","Tissue RNA - stomach 1 [nTPM]":"122.4","Tissue RNA - testis [nTPM]":"8.7","Tissue RNA - thalamus [nTPM]":"13.2","Tissue RNA - thymus [nTPM]":"8.0","Tissue RNA - thyroid gland [nTPM]":"4.7","Tissue RNA - tongue [nTPM]":"5.4","Tissue RNA - tonsil [nTPM]":"15.8","Tissue RNA - urinary bladder [nTPM]":"20.9","Tissue RNA - vagina [nTPM]":"22.2","Tissue RNA - white matter [nTPM]":"12.6","Cell RNA - A-431 [nTPM]":"60.3","Cell RNA - A549 [nTPM]":"71.5","Cell RNA - AF22 [nTPM]":"27.8","Cell RNA - AN3-CA [nTPM]":"44.5","Cell RNA - ASC diff [nTPM]":"9.8","Cell RNA - ASC TERT1 [nTPM]":"13.9","Cell RNA - BEWO [nTPM]":"26.9","Cell RNA - BJ [nTPM]":"40.7","Cell RNA - BJ hTERT+ [nTPM]":"53.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"68.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"50.9","Cell RNA - CACO-2 [nTPM]":"65.3","Cell RNA - CAPAN-2 [nTPM]":"195.4","Cell RNA - Daudi [nTPM]":"14.3","Cell RNA - EFO-21 [nTPM]":"54.7","Cell RNA - fHDF\/TERT166 [nTPM]":"23.5","Cell RNA - GAMG [nTPM]":"91.9","Cell RNA - HaCaT [nTPM]":"65.8","Cell RNA - HAP1 [nTPM]":"24.5","Cell RNA - HBEC3-KT [nTPM]":"101.8","Cell RNA - HBF TERT88 [nTPM]":"51.5","Cell RNA - HDLM-2 [nTPM]":"29.4","Cell RNA - HEK 293 [nTPM]":"16.2","Cell RNA - HEL [nTPM]":"40.6","Cell RNA - HeLa [nTPM]":"34.4","Cell RNA - Hep G2 [nTPM]":"71.6","Cell RNA - HHSteC [nTPM]":"102.0","Cell RNA - HL-60 [nTPM]":"18.4","Cell RNA - HMC-1 [nTPM]":"11.6","Cell RNA - HSkMC [nTPM]":"30.1","Cell RNA - hTCEpi [nTPM]":"53.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"63.4","Cell RNA - hTERT-HME1 [nTPM]":"156.8","Cell RNA - hTERT-RPE1 [nTPM]":"69.2","Cell RNA - HUVEC TERT2 [nTPM]":"59.5","Cell RNA - JURKAT [nTPM]":"30.1","Cell RNA - K-562 [nTPM]":"45.9","Cell RNA - Karpas-707 [nTPM]":"3.8","Cell RNA - LHCN-M2 [nTPM]":"49.5","Cell RNA - MCF7 [nTPM]":"64.5","Cell RNA - MOLT-4 [nTPM]":"29.0","Cell RNA - NB-4 [nTPM]":"19.5","Cell RNA - NTERA-2 [nTPM]":"7.8","Cell RNA - OE19 [nTPM]":"83.1","Cell RNA - PC-3 [nTPM]":"67.7","Cell RNA - REH [nTPM]":"33.6","Cell RNA - RH-30 [nTPM]":"27.1","Cell RNA - RPMI-8226 [nTPM]":"18.5","Cell RNA - RPTEC TERT1 [nTPM]":"112.7","Cell RNA - RT4 [nTPM]":"41.4","Cell RNA - SCLC-21H [nTPM]":"10.7","Cell RNA - SH-SY5Y [nTPM]":"24.1","Cell RNA - SiHa [nTPM]":"73.9","Cell RNA - SK-BR-3 [nTPM]":"66.7","Cell RNA - SK-MEL-30 [nTPM]":"70.6","Cell RNA - SuSa [nTPM]":"31.1","Cell RNA - T-47d [nTPM]":"47.9","Cell RNA - THP-1 [nTPM]":"14.5","Cell RNA - TIME [nTPM]":"33.7","Cell RNA - U-138 MG [nTPM]":"52.0","Cell RNA - U-2 OS [nTPM]":"74.9","Cell RNA - U-2197 [nTPM]":"52.0","Cell RNA - U-251 MG [nTPM]":"50.3","Cell RNA - U-266\/70 [nTPM]":"18.5","Cell RNA - U-266\/84 [nTPM]":"46.4","Cell RNA - U-698 [nTPM]":"18.9","Cell RNA - U-87 MG [nTPM]":"53.0","Cell RNA - U-937 [nTPM]":"74.5","Cell RNA - WM-115 [nTPM]":"27.8","Blood RNA - basophil [nTPM]":"1.7","Blood RNA - classical monocyte [nTPM]":"13.5","Blood RNA - eosinophil [nTPM]":"3.0","Blood RNA - gdT-cell [nTPM]":"8.5","Blood RNA - intermediate monocyte [nTPM]":"29.3","Blood RNA - MAIT T-cell [nTPM]":"8.5","Blood RNA - memory B-cell [nTPM]":"5.4","Blood RNA - memory CD4 T-cell [nTPM]":"5.0","Blood RNA - memory CD8 T-cell [nTPM]":"6.9","Blood RNA - myeloid DC [nTPM]":"19.0","Blood RNA - naive B-cell [nTPM]":"1.7","Blood RNA - naive CD4 T-cell [nTPM]":"5.8","Blood RNA - naive CD8 T-cell [nTPM]":"4.1","Blood RNA - neutrophil [nTPM]":"3.4","Blood RNA - NK-cell [nTPM]":"37.3","Blood RNA - non-classical monocyte [nTPM]":"37.1","Blood RNA - plasmacytoid DC [nTPM]":"5.2","Blood RNA - T-reg [nTPM]":"9.5","Blood RNA - total PBMC [nTPM]":"8.8","Brain RNA - amygdala [nTPM]":"12.3","Brain RNA - basal ganglia [nTPM]":"12.5","Brain RNA - cerebellum [nTPM]":"12.2","Brain RNA - cerebral cortex [nTPM]":"17.7","Brain RNA - hippocampal formation [nTPM]":"12.5","Brain RNA - hypothalamus [nTPM]":"12.5","Brain RNA - medulla oblongata [nTPM]":"12.5","Brain RNA - midbrain [nTPM]":"12.3","Brain RNA - pons [nTPM]":"12.4","Brain RNA - spinal cord [nTPM]":"12.6","Brain RNA - thalamus [nTPM]":"13.2","Brain RNA - white matter [nTPM]":"12.6","Single Cell Type RNA - Adipocytes [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"49.3","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"7.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"110.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"17.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"37.1","Single Cell Type RNA - Club cells [nTPM]":"90.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"54.1","Single Cell Type RNA - dendritic cells [nTPM]":"7.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"131.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"67.6","Single Cell Type RNA - Early spermatids [nTPM]":"21.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.1","Single Cell Type RNA - Endothelial cells [nTPM]":"14.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.1","Single Cell Type RNA - Erythroid cells [nTPM]":"8.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"114.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"106.3","Single Cell Type RNA - Fibroblasts [nTPM]":"14.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"276.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"36.2","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"17.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.8","Single Cell Type RNA - Hepatocytes [nTPM]":"38.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"99.3","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"149.5","Single Cell Type RNA - Ionocytes [nTPM]":"73.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.7","Single Cell Type RNA - Langerhans cells [nTPM]":"6.8","Single Cell Type RNA - Late spermatids [nTPM]":"5.0","Single Cell Type RNA - Leydig cells [nTPM]":"4.7","Single Cell Type RNA - Macrophages [nTPM]":"12.5","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"19.4","Single Cell Type RNA - Muller glia cells [nTPM]":"21.2","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"92.0","Single Cell Type RNA - Paneth cells [nTPM]":"109.0","Single Cell Type RNA - Peritubular cells [nTPM]":"3.4","Single Cell Type RNA - Plasma cells [nTPM]":"9.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"24.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"78.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"89.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"37.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.1","Single Cell Type RNA - Spermatocytes [nTPM]":"14.5","Single Cell Type RNA - Spermatogonia [nTPM]":"9.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"96.3","Single Cell Type RNA - T-cells [nTPM]":"7.6","Single Cell Type RNA - Theca cells [nTPM]":"99.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"73.8","Single Cell Type RNA - Urothelial cells [nTPM]":"46.0"},{"Gene":"GALK1","Gene synonym":["GALK"],"Ensembl":"ENSG00000108479","Gene description":"Galactokinase 1","Uniprot":["P51570"],"Chromosome":"17","Position":"75751594-75765236","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism","Galactose metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"126.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"100.1","Hepatocytes":"116.7","Proximal enterocytes":"139.4","Proximal tubular cells":"122.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"42.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007094","HPA016960"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"57000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Cytosol"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA007094":"AB_1078939","HPA016960":"AB_1849430"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.55e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.62e-5"},"Tissue RNA - adipose tissue [nTPM]":"18.6","Tissue RNA - adrenal gland [nTPM]":"12.5","Tissue RNA - amygdala [nTPM]":"5.9","Tissue RNA - appendix [nTPM]":"7.8","Tissue RNA - basal ganglia [nTPM]":"6.7","Tissue RNA - bone marrow [nTPM]":"5.6","Tissue RNA - breast [nTPM]":"17.1","Tissue RNA - cerebellum [nTPM]":"6.4","Tissue RNA - cerebral cortex [nTPM]":"8.4","Tissue RNA - cervix [nTPM]":"17.5","Tissue RNA - choroid plexus [nTPM]":"5.9","Tissue RNA - colon [nTPM]":"12.5","Tissue RNA - duodenum [nTPM]":"20.6","Tissue RNA - endometrium 1 [nTPM]":"16.5","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"24.4","Tissue RNA - fallopian tube [nTPM]":"14.9","Tissue RNA - gallbladder [nTPM]":"4.3","Tissue RNA - heart muscle [nTPM]":"19.7","Tissue RNA - hippocampal formation [nTPM]":"6.0","Tissue RNA - hypothalamus [nTPM]":"6.6","Tissue RNA - kidney [nTPM]":"32.0","Tissue RNA - liver [nTPM]":"126.4","Tissue RNA - lung [nTPM]":"18.7","Tissue RNA - lymph node [nTPM]":"7.4","Tissue RNA - medulla oblongata [nTPM]":"7.9","Tissue RNA - midbrain [nTPM]":"6.3","Tissue RNA - ovary [nTPM]":"13.7","Tissue RNA - pancreas [nTPM]":"31.2","Tissue RNA - parathyroid gland [nTPM]":"10.6","Tissue RNA - pituitary gland [nTPM]":"5.7","Tissue RNA - placenta [nTPM]":"5.8","Tissue RNA - pons [nTPM]":"7.5","Tissue RNA - prostate [nTPM]":"13.3","Tissue RNA - rectum [nTPM]":"2.0","Tissue RNA - retina [nTPM]":"0.7","Tissue RNA - salivary gland [nTPM]":"20.0","Tissue RNA - seminal vesicle [nTPM]":"5.7","Tissue RNA - skeletal muscle [nTPM]":"8.6","Tissue RNA - skin 1 [nTPM]":"20.6","Tissue RNA - small intestine [nTPM]":"18.3","Tissue RNA - smooth muscle [nTPM]":"3.9","Tissue RNA - spinal cord [nTPM]":"7.0","Tissue RNA - spleen [nTPM]":"24.5","Tissue RNA - stomach 1 [nTPM]":"17.6","Tissue RNA - testis [nTPM]":"16.0","Tissue RNA - thalamus [nTPM]":"6.8","Tissue RNA - thymus [nTPM]":"6.1","Tissue RNA - thyroid gland [nTPM]":"11.6","Tissue RNA - tongue [nTPM]":"3.6","Tissue RNA - tonsil [nTPM]":"3.4","Tissue RNA - urinary bladder [nTPM]":"13.0","Tissue RNA - vagina [nTPM]":"17.8","Tissue RNA - white matter [nTPM]":"8.2","Cell RNA - A-431 [nTPM]":"20.4","Cell RNA - A549 [nTPM]":"65.2","Cell RNA - AF22 [nTPM]":"4.9","Cell RNA - AN3-CA [nTPM]":"20.7","Cell RNA - ASC diff [nTPM]":"6.8","Cell RNA - ASC TERT1 [nTPM]":"16.6","Cell RNA - BEWO [nTPM]":"16.7","Cell RNA - BJ [nTPM]":"16.9","Cell RNA - BJ hTERT+ [nTPM]":"14.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.8","Cell RNA - CACO-2 [nTPM]":"35.4","Cell RNA - CAPAN-2 [nTPM]":"4.2","Cell RNA - Daudi [nTPM]":"31.2","Cell RNA - EFO-21 [nTPM]":"19.5","Cell RNA - fHDF\/TERT166 [nTPM]":"9.3","Cell RNA - GAMG [nTPM]":"12.6","Cell RNA - HaCaT [nTPM]":"11.9","Cell RNA - HAP1 [nTPM]":"5.0","Cell RNA - HBEC3-KT [nTPM]":"4.4","Cell RNA - HBF TERT88 [nTPM]":"1.9","Cell RNA - HDLM-2 [nTPM]":"14.2","Cell RNA - HEK 293 [nTPM]":"39.3","Cell RNA - HEL [nTPM]":"20.1","Cell RNA - HeLa [nTPM]":"25.1","Cell RNA - Hep G2 [nTPM]":"62.4","Cell RNA - HHSteC [nTPM]":"22.1","Cell RNA - HL-60 [nTPM]":"13.0","Cell RNA - HMC-1 [nTPM]":"41.9","Cell RNA - HSkMC [nTPM]":"15.3","Cell RNA - hTCEpi [nTPM]":"6.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.5","Cell RNA - hTERT-HME1 [nTPM]":"3.5","Cell RNA - hTERT-RPE1 [nTPM]":"8.5","Cell RNA - HUVEC TERT2 [nTPM]":"39.1","Cell RNA - JURKAT [nTPM]":"16.9","Cell RNA - K-562 [nTPM]":"15.9","Cell RNA - Karpas-707 [nTPM]":"21.2","Cell RNA - LHCN-M2 [nTPM]":"11.7","Cell RNA - MCF7 [nTPM]":"77.3","Cell RNA - MOLT-4 [nTPM]":"38.6","Cell RNA - NB-4 [nTPM]":"44.7","Cell RNA - NTERA-2 [nTPM]":"4.7","Cell RNA - OE19 [nTPM]":"9.8","Cell RNA - PC-3 [nTPM]":"32.3","Cell RNA - REH [nTPM]":"43.6","Cell RNA - RH-30 [nTPM]":"50.1","Cell RNA - RPMI-8226 [nTPM]":"50.9","Cell RNA - RPTEC TERT1 [nTPM]":"9.8","Cell RNA - RT4 [nTPM]":"7.3","Cell RNA - SCLC-21H [nTPM]":"9.9","Cell RNA - SH-SY5Y [nTPM]":"26.1","Cell RNA - SiHa [nTPM]":"14.6","Cell RNA - SK-BR-3 [nTPM]":"35.8","Cell RNA - SK-MEL-30 [nTPM]":"35.0","Cell RNA - SuSa [nTPM]":"3.8","Cell RNA - T-47d [nTPM]":"29.8","Cell RNA - THP-1 [nTPM]":"20.9","Cell RNA - TIME [nTPM]":"33.4","Cell RNA - U-138 MG [nTPM]":"24.3","Cell RNA - U-2 OS [nTPM]":"22.3","Cell RNA - U-2197 [nTPM]":"21.7","Cell RNA - U-251 MG [nTPM]":"14.6","Cell RNA - U-266\/70 [nTPM]":"44.4","Cell RNA - U-266\/84 [nTPM]":"12.4","Cell RNA - U-698 [nTPM]":"8.2","Cell RNA - U-87 MG [nTPM]":"26.7","Cell RNA - U-937 [nTPM]":"30.3","Cell RNA - WM-115 [nTPM]":"18.3","Blood RNA - basophil [nTPM]":"7.2","Blood RNA - classical monocyte [nTPM]":"77.2","Blood RNA - eosinophil [nTPM]":"23.0","Blood RNA - gdT-cell [nTPM]":"23.0","Blood RNA - intermediate monocyte [nTPM]":"67.8","Blood RNA - MAIT T-cell [nTPM]":"20.8","Blood RNA - memory B-cell [nTPM]":"27.7","Blood RNA - memory CD4 T-cell [nTPM]":"18.5","Blood RNA - memory CD8 T-cell [nTPM]":"21.2","Blood RNA - myeloid DC [nTPM]":"70.1","Blood RNA - naive B-cell [nTPM]":"18.9","Blood RNA - naive CD4 T-cell [nTPM]":"10.0","Blood RNA - naive CD8 T-cell [nTPM]":"14.5","Blood RNA - neutrophil [nTPM]":"53.1","Blood RNA - NK-cell [nTPM]":"16.2","Blood RNA - non-classical monocyte [nTPM]":"55.6","Blood RNA - plasmacytoid DC [nTPM]":"93.3","Blood RNA - T-reg [nTPM]":"23.6","Blood RNA - total PBMC [nTPM]":"40.8","Brain RNA - amygdala [nTPM]":"5.9","Brain RNA - basal ganglia [nTPM]":"6.7","Brain RNA - cerebellum [nTPM]":"6.4","Brain RNA - cerebral cortex [nTPM]":"8.4","Brain RNA - hippocampal formation [nTPM]":"6.0","Brain RNA - hypothalamus [nTPM]":"6.6","Brain RNA - medulla oblongata [nTPM]":"7.9","Brain RNA - midbrain [nTPM]":"6.3","Brain RNA - pons [nTPM]":"7.5","Brain RNA - spinal cord [nTPM]":"7.0","Brain RNA - thalamus [nTPM]":"6.8","Brain RNA - white matter [nTPM]":"8.2","Single Cell Type RNA - Adipocytes [nTPM]":"42.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.9","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"17.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"7.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"22.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"10.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"48.4","Single Cell Type RNA - dendritic cells [nTPM]":"16.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"68.4","Single Cell Type RNA - Ductal cells [nTPM]":"28.5","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"24.5","Single Cell Type RNA - Endothelial cells [nTPM]":"23.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"9.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"55.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"100.1","Single Cell Type RNA - Fibroblasts [nTPM]":"25.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.6","Single Cell Type RNA - granulocytes [nTPM]":"27.9","Single Cell Type RNA - Granulosa cells [nTPM]":"16.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"29.3","Single Cell Type RNA - Hepatocytes [nTPM]":"116.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"56.1","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.9","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"49.0","Single Cell Type RNA - Langerhans cells [nTPM]":"25.2","Single Cell Type RNA - Late spermatids [nTPM]":"5.6","Single Cell Type RNA - Leydig cells [nTPM]":"31.1","Single Cell Type RNA - Macrophages [nTPM]":"33.3","Single Cell Type RNA - Melanocytes [nTPM]":"39.2","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"42.3","Single Cell Type RNA - Muller glia cells [nTPM]":"19.2","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.3","Single Cell Type RNA - Paneth cells [nTPM]":"49.6","Single Cell Type RNA - Peritubular cells [nTPM]":"24.0","Single Cell Type RNA - Plasma cells [nTPM]":"29.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"139.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"122.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.8","Single Cell Type RNA - Spermatocytes [nTPM]":"1.7","Single Cell Type RNA - Spermatogonia [nTPM]":"22.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"42.3","Single Cell Type RNA - T-cells [nTPM]":"14.9","Single Cell Type RNA - Theca cells [nTPM]":"6.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"28.2","Single Cell Type RNA - Urothelial cells [nTPM]":"9.2"},{"Gene":"GALM","Gene synonym":[],"Ensembl":"ENSG00000143891","Gene description":"Galactose mutarotase","Uniprot":["Q96C23"],"Chromosome":"2","Position":"38666081-38741237","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism"],"Molecular function":["Isomerase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"86.5","kidney":"120.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Peritubular cells":"97.8","Proximal enterocytes":"161.1","Proximal tubular cells":"222.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"68.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"39.1","T-cells":"68.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"62.7","Karpas-707":"71.1","U-266\/70":"76.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035472","HPA035473","HPA064835"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"620000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA035472":"AB_10669906","HPA035473":"AB_2674642","HPA064835":"AB_2732723"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.99e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.06e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.32e-4"},"Tissue RNA - adipose tissue [nTPM]":"9.0","Tissue RNA - adrenal gland [nTPM]":"86.5","Tissue RNA - amygdala [nTPM]":"5.2","Tissue RNA - appendix [nTPM]":"12.2","Tissue RNA - basal ganglia [nTPM]":"5.1","Tissue RNA - bone marrow [nTPM]":"3.8","Tissue RNA - breast [nTPM]":"10.4","Tissue RNA - cerebellum [nTPM]":"6.0","Tissue RNA - cerebral cortex [nTPM]":"6.1","Tissue RNA - cervix [nTPM]":"9.3","Tissue RNA - choroid plexus [nTPM]":"8.3","Tissue RNA - colon [nTPM]":"34.7","Tissue RNA - duodenum [nTPM]":"71.4","Tissue RNA - endometrium 1 [nTPM]":"8.1","Tissue RNA - epididymis [nTPM]":"23.0","Tissue RNA - esophagus [nTPM]":"5.8","Tissue RNA - fallopian tube [nTPM]":"35.8","Tissue RNA - gallbladder [nTPM]":"16.5","Tissue RNA - heart muscle [nTPM]":"13.0","Tissue RNA - hippocampal formation [nTPM]":"4.9","Tissue RNA - hypothalamus [nTPM]":"4.8","Tissue RNA - kidney [nTPM]":"120.2","Tissue RNA - liver [nTPM]":"72.5","Tissue RNA - lung [nTPM]":"14.3","Tissue RNA - lymph node [nTPM]":"16.0","Tissue RNA - medulla oblongata [nTPM]":"5.4","Tissue RNA - midbrain [nTPM]":"6.1","Tissue RNA - ovary [nTPM]":"15.5","Tissue RNA - pancreas [nTPM]":"15.0","Tissue RNA - parathyroid gland [nTPM]":"21.3","Tissue RNA - pituitary gland [nTPM]":"3.0","Tissue RNA - placenta [nTPM]":"7.7","Tissue RNA - pons [nTPM]":"5.4","Tissue RNA - prostate [nTPM]":"10.2","Tissue RNA - rectum [nTPM]":"33.3","Tissue RNA - retina [nTPM]":"4.4","Tissue RNA - salivary gland [nTPM]":"8.7","Tissue RNA - seminal vesicle [nTPM]":"20.8","Tissue RNA - skeletal muscle [nTPM]":"13.1","Tissue RNA - skin 1 [nTPM]":"3.8","Tissue RNA - small intestine [nTPM]":"52.8","Tissue RNA - smooth muscle [nTPM]":"10.4","Tissue RNA - spinal cord [nTPM]":"5.7","Tissue RNA - spleen [nTPM]":"6.6","Tissue RNA - stomach 1 [nTPM]":"14.9","Tissue RNA - testis [nTPM]":"4.4","Tissue RNA - thalamus [nTPM]":"7.0","Tissue RNA - thymus [nTPM]":"11.0","Tissue RNA - thyroid gland [nTPM]":"15.1","Tissue RNA - tongue [nTPM]":"12.3","Tissue RNA - tonsil [nTPM]":"10.2","Tissue RNA - urinary bladder [nTPM]":"10.8","Tissue RNA - vagina [nTPM]":"6.4","Tissue RNA - white matter [nTPM]":"6.0","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"27.1","Cell RNA - AF22 [nTPM]":"8.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"27.3","Cell RNA - ASC TERT1 [nTPM]":"15.4","Cell RNA - BEWO [nTPM]":"14.9","Cell RNA - BJ [nTPM]":"3.2","Cell RNA - BJ hTERT+ [nTPM]":"10.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.2","Cell RNA - CACO-2 [nTPM]":"32.4","Cell RNA - CAPAN-2 [nTPM]":"14.4","Cell RNA - Daudi [nTPM]":"10.9","Cell RNA - EFO-21 [nTPM]":"18.9","Cell RNA - fHDF\/TERT166 [nTPM]":"15.3","Cell RNA - GAMG [nTPM]":"14.5","Cell RNA - HaCaT [nTPM]":"4.3","Cell RNA - HAP1 [nTPM]":"11.7","Cell RNA - HBEC3-KT [nTPM]":"0.7","Cell RNA - HBF TERT88 [nTPM]":"14.5","Cell RNA - HDLM-2 [nTPM]":"49.5","Cell RNA - HEK 293 [nTPM]":"19.3","Cell RNA - HEL [nTPM]":"5.9","Cell RNA - HeLa [nTPM]":"7.1","Cell RNA - Hep G2 [nTPM]":"62.7","Cell RNA - HHSteC [nTPM]":"10.0","Cell RNA - HL-60 [nTPM]":"2.4","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"11.1","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"17.5","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"10.5","Cell RNA - HUVEC TERT2 [nTPM]":"8.2","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"17.2","Cell RNA - Karpas-707 [nTPM]":"71.1","Cell RNA - LHCN-M2 [nTPM]":"13.9","Cell RNA - MCF7 [nTPM]":"0.9","Cell RNA - MOLT-4 [nTPM]":"23.4","Cell RNA - NB-4 [nTPM]":"41.0","Cell RNA - NTERA-2 [nTPM]":"12.4","Cell RNA - OE19 [nTPM]":"59.2","Cell RNA - PC-3 [nTPM]":"8.6","Cell RNA - REH [nTPM]":"15.2","Cell RNA - RH-30 [nTPM]":"0.6","Cell RNA - RPMI-8226 [nTPM]":"21.3","Cell RNA - RPTEC TERT1 [nTPM]":"9.3","Cell RNA - RT4 [nTPM]":"45.1","Cell RNA - SCLC-21H [nTPM]":"1.5","Cell RNA - SH-SY5Y [nTPM]":"11.2","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"18.9","Cell RNA - SK-MEL-30 [nTPM]":"14.7","Cell RNA - SuSa [nTPM]":"10.2","Cell RNA - T-47d [nTPM]":"9.0","Cell RNA - THP-1 [nTPM]":"5.4","Cell RNA - TIME [nTPM]":"3.4","Cell RNA - U-138 MG [nTPM]":"2.5","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"18.6","Cell RNA - U-251 MG [nTPM]":"1.0","Cell RNA - U-266\/70 [nTPM]":"76.4","Cell RNA - U-266\/84 [nTPM]":"54.3","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"17.9","Cell RNA - U-937 [nTPM]":"7.0","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"39.1","Blood RNA - classical monocyte [nTPM]":"4.8","Blood RNA - eosinophil [nTPM]":"4.2","Blood RNA - gdT-cell [nTPM]":"21.5","Blood RNA - intermediate monocyte [nTPM]":"3.3","Blood RNA - MAIT T-cell [nTPM]":"31.8","Blood RNA - memory B-cell [nTPM]":"6.8","Blood RNA - memory CD4 T-cell [nTPM]":"33.1","Blood RNA - memory CD8 T-cell [nTPM]":"31.2","Blood RNA - myeloid DC [nTPM]":"10.3","Blood RNA - naive B-cell [nTPM]":"4.7","Blood RNA - naive CD4 T-cell [nTPM]":"11.7","Blood RNA - naive CD8 T-cell [nTPM]":"10.2","Blood RNA - neutrophil [nTPM]":"11.3","Blood RNA - NK-cell [nTPM]":"5.5","Blood RNA - non-classical monocyte [nTPM]":"0.7","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"68.3","Blood RNA - total PBMC [nTPM]":"11.9","Brain RNA - amygdala [nTPM]":"5.2","Brain RNA - basal ganglia [nTPM]":"5.1","Brain RNA - cerebellum [nTPM]":"6.0","Brain RNA - cerebral cortex [nTPM]":"6.1","Brain RNA - hippocampal formation [nTPM]":"4.9","Brain RNA - hypothalamus [nTPM]":"4.8","Brain RNA - medulla oblongata [nTPM]":"5.4","Brain RNA - midbrain [nTPM]":"6.1","Brain RNA - pons [nTPM]":"5.4","Brain RNA - spinal cord [nTPM]":"5.7","Brain RNA - thalamus [nTPM]":"7.0","Brain RNA - white matter [nTPM]":"6.0","Single Cell Type RNA - Adipocytes [nTPM]":"9.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.0","Single Cell Type RNA - Astrocytes [nTPM]":"13.4","Single Cell Type RNA - B-cells [nTPM]":"10.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"3.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"23.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"6.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"69.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.6","Single Cell Type RNA - dendritic cells [nTPM]":"19.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"83.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"25.4","Single Cell Type RNA - Ductal cells [nTPM]":"12.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"28.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.6","Single Cell Type RNA - Endothelial cells [nTPM]":"10.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.2","Single Cell Type RNA - Erythroid cells [nTPM]":"8.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"31.4","Single Cell Type RNA - Fibroblasts [nTPM]":"16.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.1","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"16.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"48.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"94.8","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"40.5","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"18.6","Single Cell Type RNA - Langerhans cells [nTPM]":"43.6","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"20.2","Single Cell Type RNA - Macrophages [nTPM]":"34.7","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"9.9","Single Cell Type RNA - Muller glia cells [nTPM]":"38.2","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.8","Single Cell Type RNA - Paneth cells [nTPM]":"64.5","Single Cell Type RNA - Peritubular cells [nTPM]":"97.8","Single Cell Type RNA - Plasma cells [nTPM]":"14.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"161.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"222.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.4","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"2.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.3","Single Cell Type RNA - T-cells [nTPM]":"44.0","Single Cell Type RNA - Theca cells [nTPM]":"43.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"80.4","Single Cell Type RNA - Urothelial cells [nTPM]":"5.7"},{"Gene":"GALNS","Gene synonym":["GALNAC6S","GAS"],"Ensembl":"ENSG00000141012","Gene description":"Galactosamine (N-acetyl)-6-sulfatase","Uniprot":["P34059"],"Chromosome":"16","Position":"88813734-88856970","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Dwarfism","Mucopolysaccharidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"51.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"11.3","granulocytes":"31.3","monocytes":"17.4"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB026404","HPA042433","HPA074225"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2000000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB026404":null,"HPA042433":"AB_2732499","HPA074225":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.66e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.2","Tissue RNA - adrenal gland [nTPM]":"12.8","Tissue RNA - amygdala [nTPM]":"9.4","Tissue RNA - appendix [nTPM]":"9.3","Tissue RNA - basal ganglia [nTPM]":"10.0","Tissue RNA - bone marrow [nTPM]":"22.2","Tissue RNA - breast [nTPM]":"6.3","Tissue RNA - cerebellum [nTPM]":"10.0","Tissue RNA - cerebral cortex [nTPM]":"11.5","Tissue RNA - cervix [nTPM]":"9.1","Tissue RNA - choroid plexus [nTPM]":"22.1","Tissue RNA - colon [nTPM]":"10.0","Tissue RNA - duodenum [nTPM]":"10.6","Tissue RNA - endometrium 1 [nTPM]":"7.4","Tissue RNA - epididymis [nTPM]":"14.5","Tissue RNA - esophagus [nTPM]":"8.8","Tissue RNA - fallopian tube [nTPM]":"11.4","Tissue RNA - gallbladder [nTPM]":"9.7","Tissue RNA - heart muscle [nTPM]":"11.0","Tissue RNA - hippocampal formation [nTPM]":"10.6","Tissue RNA - hypothalamus [nTPM]":"12.0","Tissue RNA - kidney [nTPM]":"8.6","Tissue RNA - liver [nTPM]":"8.1","Tissue RNA - lung [nTPM]":"10.4","Tissue RNA - lymph node [nTPM]":"7.4","Tissue RNA - medulla oblongata [nTPM]":"12.6","Tissue RNA - midbrain [nTPM]":"16.4","Tissue RNA - ovary [nTPM]":"6.7","Tissue RNA - pancreas [nTPM]":"5.0","Tissue RNA - parathyroid gland [nTPM]":"8.6","Tissue RNA - pituitary gland [nTPM]":"11.9","Tissue RNA - placenta [nTPM]":"8.6","Tissue RNA - pons [nTPM]":"12.0","Tissue RNA - prostate [nTPM]":"7.7","Tissue RNA - rectum [nTPM]":"6.1","Tissue RNA - retina [nTPM]":"3.3","Tissue RNA - salivary gland [nTPM]":"8.3","Tissue RNA - seminal vesicle [nTPM]":"4.7","Tissue RNA - skeletal muscle [nTPM]":"6.4","Tissue RNA - skin 1 [nTPM]":"8.4","Tissue RNA - small intestine [nTPM]":"10.6","Tissue RNA - smooth muscle [nTPM]":"7.1","Tissue RNA - spinal cord [nTPM]":"10.8","Tissue RNA - spleen [nTPM]":"9.1","Tissue RNA - stomach 1 [nTPM]":"8.1","Tissue RNA - testis [nTPM]":"26.3","Tissue RNA - thalamus [nTPM]":"11.3","Tissue RNA - thymus [nTPM]":"4.8","Tissue RNA - thyroid gland [nTPM]":"9.1","Tissue RNA - tongue [nTPM]":"3.6","Tissue RNA - tonsil [nTPM]":"5.6","Tissue RNA - urinary bladder [nTPM]":"9.0","Tissue RNA - vagina [nTPM]":"9.1","Tissue RNA - white matter [nTPM]":"12.0","Cell RNA - A-431 [nTPM]":"5.7","Cell RNA - A549 [nTPM]":"42.7","Cell RNA - AF22 [nTPM]":"6.2","Cell RNA - AN3-CA [nTPM]":"43.4","Cell RNA - ASC diff [nTPM]":"47.1","Cell RNA - ASC TERT1 [nTPM]":"22.4","Cell RNA - BEWO [nTPM]":"41.9","Cell RNA - BJ [nTPM]":"17.9","Cell RNA - BJ hTERT+ [nTPM]":"27.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.7","Cell RNA - CACO-2 [nTPM]":"22.7","Cell RNA - CAPAN-2 [nTPM]":"36.8","Cell RNA - Daudi [nTPM]":"7.1","Cell RNA - EFO-21 [nTPM]":"37.1","Cell RNA - fHDF\/TERT166 [nTPM]":"29.2","Cell RNA - GAMG [nTPM]":"28.8","Cell RNA - HaCaT [nTPM]":"33.0","Cell RNA - HAP1 [nTPM]":"9.0","Cell RNA - HBEC3-KT [nTPM]":"14.2","Cell RNA - HBF TERT88 [nTPM]":"11.4","Cell RNA - HDLM-2 [nTPM]":"4.7","Cell RNA - HEK 293 [nTPM]":"13.8","Cell RNA - HEL [nTPM]":"4.5","Cell RNA - HeLa [nTPM]":"17.0","Cell RNA - Hep G2 [nTPM]":"13.2","Cell RNA - HHSteC [nTPM]":"31.5","Cell RNA - HL-60 [nTPM]":"3.6","Cell RNA - HMC-1 [nTPM]":"28.5","Cell RNA - HSkMC [nTPM]":"31.4","Cell RNA - hTCEpi [nTPM]":"26.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.4","Cell RNA - hTERT-HME1 [nTPM]":"6.0","Cell RNA - hTERT-RPE1 [nTPM]":"27.0","Cell RNA - HUVEC TERT2 [nTPM]":"16.4","Cell RNA - JURKAT [nTPM]":"7.8","Cell RNA - K-562 [nTPM]":"9.9","Cell RNA - Karpas-707 [nTPM]":"4.1","Cell RNA - LHCN-M2 [nTPM]":"11.3","Cell RNA - MCF7 [nTPM]":"33.3","Cell RNA - MOLT-4 [nTPM]":"9.2","Cell RNA - NB-4 [nTPM]":"15.0","Cell RNA - NTERA-2 [nTPM]":"14.2","Cell RNA - OE19 [nTPM]":"14.3","Cell RNA - PC-3 [nTPM]":"19.6","Cell RNA - REH [nTPM]":"19.6","Cell RNA - RH-30 [nTPM]":"5.4","Cell RNA - RPMI-8226 [nTPM]":"12.1","Cell RNA - RPTEC TERT1 [nTPM]":"11.9","Cell RNA - RT4 [nTPM]":"13.2","Cell RNA - SCLC-21H [nTPM]":"15.8","Cell RNA - SH-SY5Y [nTPM]":"12.2","Cell RNA - SiHa [nTPM]":"42.4","Cell RNA - SK-BR-3 [nTPM]":"4.0","Cell RNA - SK-MEL-30 [nTPM]":"21.9","Cell RNA - SuSa [nTPM]":"14.4","Cell RNA - T-47d [nTPM]":"27.3","Cell RNA - THP-1 [nTPM]":"32.5","Cell RNA - TIME [nTPM]":"31.3","Cell RNA - U-138 MG [nTPM]":"41.8","Cell RNA - U-2 OS [nTPM]":"31.5","Cell RNA - U-2197 [nTPM]":"43.2","Cell RNA - U-251 MG [nTPM]":"10.0","Cell RNA - U-266\/70 [nTPM]":"4.3","Cell RNA - U-266\/84 [nTPM]":"4.5","Cell RNA - U-698 [nTPM]":"12.6","Cell RNA - U-87 MG [nTPM]":"45.2","Cell RNA - U-937 [nTPM]":"29.7","Cell RNA - WM-115 [nTPM]":"25.4","Blood RNA - basophil [nTPM]":"1.4","Blood RNA - classical monocyte [nTPM]":"17.4","Blood RNA - eosinophil [nTPM]":"31.3","Blood RNA - gdT-cell [nTPM]":"4.5","Blood RNA - intermediate monocyte [nTPM]":"12.5","Blood RNA - MAIT T-cell [nTPM]":"3.9","Blood RNA - memory B-cell [nTPM]":"3.0","Blood RNA - memory CD4 T-cell [nTPM]":"2.5","Blood RNA - memory CD8 T-cell [nTPM]":"4.0","Blood RNA - myeloid DC [nTPM]":"11.3","Blood RNA - naive B-cell [nTPM]":"1.3","Blood RNA - naive CD4 T-cell [nTPM]":"2.5","Blood RNA - naive CD8 T-cell [nTPM]":"3.1","Blood RNA - neutrophil [nTPM]":"21.7","Blood RNA - NK-cell [nTPM]":"4.0","Blood RNA - non-classical monocyte [nTPM]":"9.6","Blood RNA - plasmacytoid DC [nTPM]":"4.7","Blood RNA - T-reg [nTPM]":"4.6","Blood RNA - total PBMC [nTPM]":"8.5","Brain RNA - amygdala [nTPM]":"9.4","Brain RNA - basal ganglia [nTPM]":"10.0","Brain RNA - cerebellum [nTPM]":"10.0","Brain RNA - cerebral cortex [nTPM]":"11.5","Brain RNA - hippocampal formation [nTPM]":"10.6","Brain RNA - hypothalamus [nTPM]":"12.0","Brain RNA - medulla oblongata [nTPM]":"12.6","Brain RNA - midbrain [nTPM]":"16.4","Brain RNA - pons [nTPM]":"12.0","Brain RNA - spinal cord [nTPM]":"10.8","Brain RNA - thalamus [nTPM]":"11.3","Brain RNA - white matter [nTPM]":"12.0","Single Cell Type RNA - Adipocytes [nTPM]":"4.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"5.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"27.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"5.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"11.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.9","Single Cell Type RNA - dendritic cells [nTPM]":"8.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.7","Single Cell Type RNA - Early spermatids [nTPM]":"21.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.6","Single Cell Type RNA - Endothelial cells [nTPM]":"7.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.0","Single Cell Type RNA - Fibroblasts [nTPM]":"13.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.9","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"11.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"6.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.7","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.8","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"13.2","Single Cell Type RNA - Langerhans cells [nTPM]":"6.3","Single Cell Type RNA - Late spermatids [nTPM]":"37.3","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"11.3","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"18.2","Single Cell Type RNA - Muller glia cells [nTPM]":"8.8","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.6","Single Cell Type RNA - Paneth cells [nTPM]":"13.6","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"9.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"35.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.0","Single Cell Type RNA - Spermatocytes [nTPM]":"51.3","Single Cell Type RNA - Spermatogonia [nTPM]":"42.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.9","Single Cell Type RNA - T-cells [nTPM]":"7.9","Single Cell Type RNA - Theca cells [nTPM]":"16.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.1","Single Cell Type RNA - Urothelial cells [nTPM]":"6.8"},{"Gene":"GALNT11","Gene synonym":["GalNAc-T11"],"Ensembl":"ENSG00000178234","Gene description":"Polypeptide N-acetylgalactosaminyltransferase 11","Uniprot":["Q8NCW6"],"Chromosome":"7","Position":"152025674-152122340","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Notch signaling pathway"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Heterotaxy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"408.0","kidney":"229.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"131.1","Inhibitory neurons":"130.7","Proximal tubular cells":"196.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"30.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039330"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039330":"AB_10795249"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.54e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.24e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.51e-2"},"Tissue RNA - adipose tissue [nTPM]":"32.4","Tissue RNA - adrenal gland [nTPM]":"25.4","Tissue RNA - amygdala [nTPM]":"27.9","Tissue RNA - appendix [nTPM]":"15.2","Tissue RNA - basal ganglia [nTPM]":"30.7","Tissue RNA - bone marrow [nTPM]":"12.7","Tissue RNA - breast [nTPM]":"29.0","Tissue RNA - cerebellum [nTPM]":"24.1","Tissue RNA - cerebral cortex [nTPM]":"29.3","Tissue RNA - cervix [nTPM]":"23.7","Tissue RNA - choroid plexus [nTPM]":"408.0","Tissue RNA - colon [nTPM]":"21.9","Tissue RNA - duodenum [nTPM]":"14.5","Tissue RNA - endometrium 1 [nTPM]":"23.8","Tissue RNA - epididymis [nTPM]":"24.6","Tissue RNA - esophagus [nTPM]":"26.3","Tissue RNA - fallopian tube [nTPM]":"22.4","Tissue RNA - gallbladder [nTPM]":"26.1","Tissue RNA - heart muscle [nTPM]":"26.4","Tissue RNA - hippocampal formation [nTPM]":"39.1","Tissue RNA - hypothalamus [nTPM]":"25.1","Tissue RNA - kidney [nTPM]":"229.5","Tissue RNA - liver [nTPM]":"19.9","Tissue RNA - lung [nTPM]":"27.5","Tissue RNA - lymph node [nTPM]":"16.1","Tissue RNA - medulla oblongata [nTPM]":"20.8","Tissue RNA - midbrain [nTPM]":"23.9","Tissue RNA - ovary [nTPM]":"28.1","Tissue RNA - pancreas [nTPM]":"84.1","Tissue RNA - parathyroid gland [nTPM]":"58.0","Tissue RNA - pituitary gland [nTPM]":"24.4","Tissue RNA - placenta [nTPM]":"45.8","Tissue RNA - pons [nTPM]":"21.6","Tissue RNA - prostate [nTPM]":"32.3","Tissue RNA - rectum [nTPM]":"17.6","Tissue RNA - retina [nTPM]":"40.6","Tissue RNA - salivary gland [nTPM]":"22.8","Tissue RNA - seminal vesicle [nTPM]":"25.6","Tissue RNA - skeletal muscle [nTPM]":"28.4","Tissue RNA - skin 1 [nTPM]":"23.8","Tissue RNA - small intestine [nTPM]":"15.0","Tissue RNA - smooth muscle [nTPM]":"24.2","Tissue RNA - spinal cord [nTPM]":"16.9","Tissue RNA - spleen [nTPM]":"20.5","Tissue RNA - stomach 1 [nTPM]":"22.0","Tissue RNA - testis [nTPM]":"11.8","Tissue RNA - thalamus [nTPM]":"30.3","Tissue RNA - thymus [nTPM]":"23.8","Tissue RNA - thyroid gland [nTPM]":"34.4","Tissue RNA - tongue [nTPM]":"26.0","Tissue RNA - tonsil [nTPM]":"17.8","Tissue RNA - urinary bladder [nTPM]":"24.2","Tissue RNA - vagina [nTPM]":"24.0","Tissue RNA - white matter [nTPM]":"27.0","Cell RNA - A-431 [nTPM]":"28.9","Cell RNA - A549 [nTPM]":"25.4","Cell RNA - AF22 [nTPM]":"36.8","Cell RNA - AN3-CA [nTPM]":"41.2","Cell RNA - ASC diff [nTPM]":"83.1","Cell RNA - ASC TERT1 [nTPM]":"81.3","Cell RNA - BEWO [nTPM]":"37.7","Cell RNA - BJ [nTPM]":"22.6","Cell RNA - BJ hTERT+ [nTPM]":"25.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.4","Cell RNA - CACO-2 [nTPM]":"20.7","Cell RNA - CAPAN-2 [nTPM]":"29.7","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"57.8","Cell RNA - fHDF\/TERT166 [nTPM]":"36.8","Cell RNA - GAMG [nTPM]":"51.8","Cell RNA - HaCaT [nTPM]":"13.3","Cell RNA - HAP1 [nTPM]":"17.6","Cell RNA - HBEC3-KT [nTPM]":"31.9","Cell RNA - HBF TERT88 [nTPM]":"22.8","Cell RNA - HDLM-2 [nTPM]":"23.5","Cell RNA - HEK 293 [nTPM]":"26.3","Cell RNA - HEL [nTPM]":"5.8","Cell RNA - HeLa [nTPM]":"23.4","Cell RNA - Hep G2 [nTPM]":"18.2","Cell RNA - HHSteC [nTPM]":"27.3","Cell RNA - HL-60 [nTPM]":"26.2","Cell RNA - HMC-1 [nTPM]":"29.3","Cell RNA - HSkMC [nTPM]":"72.1","Cell RNA - hTCEpi [nTPM]":"40.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.5","Cell RNA - hTERT-HME1 [nTPM]":"13.0","Cell RNA - hTERT-RPE1 [nTPM]":"32.3","Cell RNA - HUVEC TERT2 [nTPM]":"34.1","Cell RNA - JURKAT [nTPM]":"19.9","Cell RNA - K-562 [nTPM]":"29.5","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"47.0","Cell RNA - MCF7 [nTPM]":"24.9","Cell RNA - MOLT-4 [nTPM]":"22.7","Cell RNA - NB-4 [nTPM]":"23.6","Cell RNA - NTERA-2 [nTPM]":"30.4","Cell RNA - OE19 [nTPM]":"45.1","Cell RNA - PC-3 [nTPM]":"20.2","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"16.1","Cell RNA - RPMI-8226 [nTPM]":"0.9","Cell RNA - RPTEC TERT1 [nTPM]":"61.1","Cell RNA - RT4 [nTPM]":"43.8","Cell RNA - SCLC-21H [nTPM]":"32.6","Cell RNA - SH-SY5Y [nTPM]":"43.3","Cell RNA - SiHa [nTPM]":"37.5","Cell RNA - SK-BR-3 [nTPM]":"18.0","Cell RNA - SK-MEL-30 [nTPM]":"31.0","Cell RNA - SuSa [nTPM]":"39.0","Cell RNA - T-47d [nTPM]":"26.8","Cell RNA - THP-1 [nTPM]":"22.3","Cell RNA - TIME [nTPM]":"31.1","Cell RNA - U-138 MG [nTPM]":"24.8","Cell RNA - U-2 OS [nTPM]":"8.8","Cell RNA - U-2197 [nTPM]":"31.6","Cell RNA - U-251 MG [nTPM]":"25.1","Cell RNA - U-266\/70 [nTPM]":"8.4","Cell RNA - U-266\/84 [nTPM]":"11.4","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"51.6","Cell RNA - U-937 [nTPM]":"25.1","Cell RNA - WM-115 [nTPM]":"86.6","Blood RNA - basophil [nTPM]":"10.2","Blood RNA - classical monocyte [nTPM]":"12.7","Blood RNA - eosinophil [nTPM]":"13.5","Blood RNA - gdT-cell [nTPM]":"28.1","Blood RNA - intermediate monocyte [nTPM]":"15.2","Blood RNA - MAIT T-cell [nTPM]":"27.8","Blood RNA - memory B-cell [nTPM]":"9.5","Blood RNA - memory CD4 T-cell [nTPM]":"15.4","Blood RNA - memory CD8 T-cell [nTPM]":"25.8","Blood RNA - myeloid DC [nTPM]":"13.0","Blood RNA - naive B-cell [nTPM]":"5.7","Blood RNA - naive CD4 T-cell [nTPM]":"13.1","Blood RNA - naive CD8 T-cell [nTPM]":"19.9","Blood RNA - neutrophil [nTPM]":"6.6","Blood RNA - NK-cell [nTPM]":"26.2","Blood RNA - non-classical monocyte [nTPM]":"21.3","Blood RNA - plasmacytoid DC [nTPM]":"4.0","Blood RNA - T-reg [nTPM]":"12.7","Blood RNA - total PBMC [nTPM]":"14.4","Brain RNA - amygdala [nTPM]":"27.9","Brain RNA - basal ganglia [nTPM]":"30.7","Brain RNA - cerebellum [nTPM]":"24.1","Brain RNA - cerebral cortex [nTPM]":"29.3","Brain RNA - hippocampal formation [nTPM]":"39.1","Brain RNA - hypothalamus [nTPM]":"25.1","Brain RNA - medulla oblongata [nTPM]":"20.8","Brain RNA - midbrain [nTPM]":"23.9","Brain RNA - pons [nTPM]":"21.6","Brain RNA - spinal cord [nTPM]":"16.9","Brain RNA - thalamus [nTPM]":"30.3","Brain RNA - white matter [nTPM]":"27.0","Single Cell Type RNA - Adipocytes [nTPM]":"28.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.2","Single Cell Type RNA - Astrocytes [nTPM]":"44.4","Single Cell Type RNA - B-cells [nTPM]":"12.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"20.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Bipolar cells [nTPM]":"123.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"30.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"16.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"35.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"84.0","Single Cell Type RNA - dendritic cells [nTPM]":"49.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"60.7","Single Cell Type RNA - Ductal cells [nTPM]":"17.8","Single Cell Type RNA - Early spermatids [nTPM]":"4.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"31.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"38.8","Single Cell Type RNA - Endothelial cells [nTPM]":"22.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.8","Single Cell Type RNA - Erythroid cells [nTPM]":"7.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"131.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.5","Single Cell Type RNA - Fibroblasts [nTPM]":"33.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"57.1","Single Cell Type RNA - granulocytes [nTPM]":"14.5","Single Cell Type RNA - Granulosa cells [nTPM]":"26.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.1","Single Cell Type RNA - Hepatocytes [nTPM]":"15.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.3","Single Cell Type RNA - Horizontal cells [nTPM]":"75.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"130.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.0","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"19.7","Single Cell Type RNA - Langerhans cells [nTPM]":"12.5","Single Cell Type RNA - Late spermatids [nTPM]":"3.5","Single Cell Type RNA - Leydig cells [nTPM]":"19.9","Single Cell Type RNA - Macrophages [nTPM]":"21.7","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"46.9","Single Cell Type RNA - monocytes [nTPM]":"18.0","Single Cell Type RNA - Muller glia cells [nTPM]":"37.8","Single Cell Type RNA - NK-cells [nTPM]":"43.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"54.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"42.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.0","Single Cell Type RNA - Paneth cells [nTPM]":"8.3","Single Cell Type RNA - Peritubular cells [nTPM]":"36.1","Single Cell Type RNA - Plasma cells [nTPM]":"20.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"26.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"196.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"39.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"36.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"25.0","Single Cell Type RNA - Spermatocytes [nTPM]":"38.7","Single Cell Type RNA - Spermatogonia [nTPM]":"27.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"24.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"36.3","Single Cell Type RNA - T-cells [nTPM]":"29.1","Single Cell Type RNA - Theca cells [nTPM]":"24.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.3","Single Cell Type RNA - Urothelial cells [nTPM]":"19.1"},{"Gene":"GALNT12","Gene synonym":["GalNAc-T12"],"Ensembl":"ENSG00000119514","Gene description":"Polypeptide N-acetylgalactosaminyltransferase 12","Uniprot":["Q8IXK2"],"Chromosome":"9","Position":"98807670-98850081","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"74.7","intestine":"55.8","stomach 1":"54.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"101.2","Intestinal goblet cells":"142.4","Undifferentiated cells":"42.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"OE19":"128.4","U-2197":"160.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048292","HPA071076"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cell Junctions"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"47000","Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 27: Mucus-secreting cells - Mucin production","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cell Junctions"],"Antibody RRID":{"HPA048292":"AB_2680343","HPA071076":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.24e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.0","Tissue RNA - adrenal gland [nTPM]":"2.0","Tissue RNA - amygdala [nTPM]":"1.2","Tissue RNA - appendix [nTPM]":"7.7","Tissue RNA - basal ganglia [nTPM]":"1.3","Tissue RNA - bone marrow [nTPM]":"2.2","Tissue RNA - breast [nTPM]":"3.4","Tissue RNA - cerebellum [nTPM]":"6.5","Tissue RNA - cerebral cortex [nTPM]":"1.8","Tissue RNA - cervix [nTPM]":"8.7","Tissue RNA - choroid plexus [nTPM]":"4.3","Tissue RNA - colon [nTPM]":"55.3","Tissue RNA - duodenum [nTPM]":"34.2","Tissue RNA - endometrium 1 [nTPM]":"3.7","Tissue RNA - epididymis [nTPM]":"74.7","Tissue RNA - esophagus [nTPM]":"19.6","Tissue RNA - fallopian tube [nTPM]":"7.5","Tissue RNA - gallbladder [nTPM]":"10.5","Tissue RNA - heart muscle [nTPM]":"1.2","Tissue RNA - hippocampal formation [nTPM]":"1.1","Tissue RNA - hypothalamus [nTPM]":"1.4","Tissue RNA - kidney [nTPM]":"4.8","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"11.7","Tissue RNA - lymph node [nTPM]":"3.2","Tissue RNA - medulla oblongata [nTPM]":"2.6","Tissue RNA - midbrain [nTPM]":"1.4","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"13.6","Tissue RNA - parathyroid gland [nTPM]":"6.3","Tissue RNA - pituitary gland [nTPM]":"3.4","Tissue RNA - placenta [nTPM]":"2.6","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"4.6","Tissue RNA - rectum [nTPM]":"55.8","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"25.5","Tissue RNA - seminal vesicle [nTPM]":"4.3","Tissue RNA - skeletal muscle [nTPM]":"1.3","Tissue RNA - skin 1 [nTPM]":"3.4","Tissue RNA - small intestine [nTPM]":"27.1","Tissue RNA - smooth muscle [nTPM]":"14.0","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"2.2","Tissue RNA - stomach 1 [nTPM]":"54.8","Tissue RNA - testis [nTPM]":"4.6","Tissue RNA - thalamus [nTPM]":"1.5","Tissue RNA - thymus [nTPM]":"3.3","Tissue RNA - thyroid gland [nTPM]":"14.7","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"6.1","Tissue RNA - urinary bladder [nTPM]":"11.9","Tissue RNA - vagina [nTPM]":"4.6","Tissue RNA - white matter [nTPM]":"1.6","Cell RNA - A-431 [nTPM]":"5.4","Cell RNA - A549 [nTPM]":"4.1","Cell RNA - AF22 [nTPM]":"3.4","Cell RNA - AN3-CA [nTPM]":"13.5","Cell RNA - ASC diff [nTPM]":"10.0","Cell RNA - ASC TERT1 [nTPM]":"7.8","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"1.4","Cell RNA - BJ hTERT+ [nTPM]":"2.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.6","Cell RNA - CACO-2 [nTPM]":"0.8","Cell RNA - CAPAN-2 [nTPM]":"21.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"5.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.9","Cell RNA - GAMG [nTPM]":"12.2","Cell RNA - HaCaT [nTPM]":"38.0","Cell RNA - HAP1 [nTPM]":"2.9","Cell RNA - HBEC3-KT [nTPM]":"1.3","Cell RNA - HBF TERT88 [nTPM]":"1.6","Cell RNA - HDLM-2 [nTPM]":"26.2","Cell RNA - HEK 293 [nTPM]":"1.7","Cell RNA - HEL [nTPM]":"2.4","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.5","Cell RNA - HL-60 [nTPM]":"1.6","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"3.8","Cell RNA - hTCEpi [nTPM]":"0.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.4","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"2.7","Cell RNA - HUVEC TERT2 [nTPM]":"2.3","Cell RNA - JURKAT [nTPM]":"19.3","Cell RNA - K-562 [nTPM]":"30.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.6","Cell RNA - MCF7 [nTPM]":"13.9","Cell RNA - MOLT-4 [nTPM]":"2.6","Cell RNA - NB-4 [nTPM]":"4.7","Cell RNA - NTERA-2 [nTPM]":"16.7","Cell RNA - OE19 [nTPM]":"128.4","Cell RNA - PC-3 [nTPM]":"5.6","Cell RNA - REH [nTPM]":"6.5","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"2.3","Cell RNA - RT4 [nTPM]":"7.7","Cell RNA - SCLC-21H [nTPM]":"12.4","Cell RNA - SH-SY5Y [nTPM]":"1.1","Cell RNA - SiHa [nTPM]":"0.5","Cell RNA - SK-BR-3 [nTPM]":"30.6","Cell RNA - SK-MEL-30 [nTPM]":"3.0","Cell RNA - SuSa [nTPM]":"7.7","Cell RNA - T-47d [nTPM]":"4.5","Cell RNA - THP-1 [nTPM]":"4.5","Cell RNA - TIME [nTPM]":"4.3","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"160.9","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"2.1","Cell RNA - U-266\/84 [nTPM]":"4.8","Cell RNA - U-698 [nTPM]":"2.3","Cell RNA - U-87 MG [nTPM]":"37.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"1.2","Brain RNA - basal ganglia [nTPM]":"1.3","Brain RNA - cerebellum [nTPM]":"6.5","Brain RNA - cerebral cortex [nTPM]":"1.8","Brain RNA - hippocampal formation [nTPM]":"1.1","Brain RNA - hypothalamus [nTPM]":"1.4","Brain RNA - medulla oblongata [nTPM]":"2.6","Brain RNA - midbrain [nTPM]":"1.4","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"1.5","Brain RNA - white matter [nTPM]":"1.6","Single Cell Type RNA - Adipocytes [nTPM]":"1.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.7","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"2.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"2.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"16.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - dendritic cells [nTPM]":"2.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"101.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"11.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.6","Single Cell Type RNA - Endothelial cells [nTPM]":"1.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.9","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.7","Single Cell Type RNA - Fibroblasts [nTPM]":"12.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.7","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"2.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"142.4","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"3.9","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"3.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"32.0","Single Cell Type RNA - Paneth cells [nTPM]":"36.5","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"1.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"21.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.5","Single Cell Type RNA - Spermatocytes [nTPM]":"5.9","Single Cell Type RNA - Spermatogonia [nTPM]":"10.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - T-cells [nTPM]":"4.5","Single Cell Type RNA - Theca cells [nTPM]":"5.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"42.5","Single Cell Type RNA - Urothelial cells [nTPM]":"11.1"},{"Gene":"GALNT17","Gene synonym":["GalNAc-T17","GalNAc-T19","GalNAc-T5L","GALNTL3","ppGalNAc-T17","WBSCR17"],"Ensembl":"ENSG00000185274","Gene description":"Polypeptide N-acetylgalactosaminyltransferase 17","Uniprot":["Q6IS24"],"Chromosome":"7","Position":"71132144-71713600","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Williams-Beuren syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"55.0","choroid plexus":"46.0","heart muscle":"43.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"1.8","Endometrial stromal cells":"7.4","Fibroblasts":"1.5","Granulosa cells":"1.7","Theca cells":"2.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"8.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"14.3","NTERA-2":"10.8","RPMI-8226":"12.6","SK-BR-3":"45.7","SuSa":"14.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013624","HPA047986"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Nucleoli","Nuclear bodies","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 36: Stromal cells - Cell proliferation","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":["Nucleoli","Nuclear bodies"],"Antibody RRID":{"HPA013624":"AB_1858787","HPA047986":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.60e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.91e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-3"},"Tissue RNA - adipose tissue [nTPM]":"3.2","Tissue RNA - adrenal gland [nTPM]":"8.7","Tissue RNA - amygdala [nTPM]":"30.5","Tissue RNA - appendix [nTPM]":"1.9","Tissue RNA - basal ganglia [nTPM]":"37.9","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"2.0","Tissue RNA - cerebellum [nTPM]":"35.9","Tissue RNA - cerebral cortex [nTPM]":"51.2","Tissue RNA - cervix [nTPM]":"4.0","Tissue RNA - choroid plexus [nTPM]":"46.0","Tissue RNA - colon [nTPM]":"16.6","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"16.6","Tissue RNA - epididymis [nTPM]":"3.1","Tissue RNA - esophagus [nTPM]":"9.3","Tissue RNA - fallopian tube [nTPM]":"8.7","Tissue RNA - gallbladder [nTPM]":"2.5","Tissue RNA - heart muscle [nTPM]":"43.5","Tissue RNA - hippocampal formation [nTPM]":"55.0","Tissue RNA - hypothalamus [nTPM]":"3.2","Tissue RNA - kidney [nTPM]":"5.7","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"9.3","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"2.1","Tissue RNA - midbrain [nTPM]":"3.8","Tissue RNA - ovary [nTPM]":"31.6","Tissue RNA - pancreas [nTPM]":"10.1","Tissue RNA - parathyroid gland [nTPM]":"1.2","Tissue RNA - pituitary gland [nTPM]":"13.3","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"14.7","Tissue RNA - rectum [nTPM]":"1.0","Tissue RNA - retina [nTPM]":"3.3","Tissue RNA - salivary gland [nTPM]":"3.3","Tissue RNA - seminal vesicle [nTPM]":"8.2","Tissue RNA - skeletal muscle [nTPM]":"4.7","Tissue RNA - skin 1 [nTPM]":"2.2","Tissue RNA - small intestine [nTPM]":"3.9","Tissue RNA - smooth muscle [nTPM]":"8.3","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"3.4","Tissue RNA - stomach 1 [nTPM]":"2.4","Tissue RNA - testis [nTPM]":"5.0","Tissue RNA - thalamus [nTPM]":"11.2","Tissue RNA - thymus [nTPM]":"2.6","Tissue RNA - thyroid gland [nTPM]":"10.1","Tissue RNA - tongue [nTPM]":"2.9","Tissue RNA - tonsil [nTPM]":"1.5","Tissue RNA - urinary bladder [nTPM]":"21.2","Tissue RNA - vagina [nTPM]":"3.3","Tissue RNA - white matter [nTPM]":"24.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"14.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"10.8","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"12.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"45.7","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"14.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"3.8","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"1.3","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"30.5","Brain RNA - basal ganglia [nTPM]":"37.9","Brain RNA - cerebellum [nTPM]":"35.9","Brain RNA - cerebral cortex [nTPM]":"51.2","Brain RNA - hippocampal formation [nTPM]":"55.0","Brain RNA - hypothalamus [nTPM]":"3.2","Brain RNA - medulla oblongata [nTPM]":"2.1","Brain RNA - midbrain [nTPM]":"3.8","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"11.2","Brain RNA - white matter [nTPM]":"24.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"2.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"GALNT2","Gene synonym":["GalNAc-T2"],"Ensembl":"ENSG00000143641","Gene description":"Polypeptide N-acetylgalactosaminyltransferase 2","Uniprot":["Q10471"],"Chromosome":"1","Position":"230057990-230282122","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Exocrine glandular cells":"133.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"WM-115":"429.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011222"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"13000000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA011222":"AB_1849446"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.22e-6"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.70e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.77e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.48e-8"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.79e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Tissue RNA - adipose tissue [nTPM]":"32.9","Tissue RNA - adrenal gland [nTPM]":"49.6","Tissue RNA - amygdala [nTPM]":"17.0","Tissue RNA - appendix [nTPM]":"34.8","Tissue RNA - basal ganglia [nTPM]":"19.9","Tissue RNA - bone marrow [nTPM]":"13.9","Tissue RNA - breast [nTPM]":"21.9","Tissue RNA - cerebellum [nTPM]":"15.2","Tissue RNA - cerebral cortex [nTPM]":"16.7","Tissue RNA - cervix [nTPM]":"24.7","Tissue RNA - choroid plexus [nTPM]":"22.0","Tissue RNA - colon [nTPM]":"28.9","Tissue RNA - duodenum [nTPM]":"19.5","Tissue RNA - endometrium 1 [nTPM]":"27.1","Tissue RNA - epididymis [nTPM]":"6.9","Tissue RNA - esophagus [nTPM]":"21.0","Tissue RNA - fallopian tube [nTPM]":"22.4","Tissue RNA - gallbladder [nTPM]":"21.2","Tissue RNA - heart muscle [nTPM]":"27.4","Tissue RNA - hippocampal formation [nTPM]":"15.8","Tissue RNA - hypothalamus [nTPM]":"18.6","Tissue RNA - kidney [nTPM]":"18.5","Tissue RNA - liver [nTPM]":"100.1","Tissue RNA - lung [nTPM]":"27.1","Tissue RNA - lymph node [nTPM]":"14.0","Tissue RNA - medulla oblongata [nTPM]":"23.0","Tissue RNA - midbrain [nTPM]":"19.5","Tissue RNA - ovary [nTPM]":"39.2","Tissue RNA - pancreas [nTPM]":"68.1","Tissue RNA - parathyroid gland [nTPM]":"9.9","Tissue RNA - pituitary gland [nTPM]":"13.6","Tissue RNA - placenta [nTPM]":"27.6","Tissue RNA - pons [nTPM]":"18.3","Tissue RNA - prostate [nTPM]":"21.4","Tissue RNA - rectum [nTPM]":"12.4","Tissue RNA - retina [nTPM]":"19.8","Tissue RNA - salivary gland [nTPM]":"22.1","Tissue RNA - seminal vesicle [nTPM]":"14.3","Tissue RNA - skeletal muscle [nTPM]":"67.4","Tissue RNA - skin 1 [nTPM]":"14.7","Tissue RNA - small intestine [nTPM]":"23.6","Tissue RNA - smooth muscle [nTPM]":"25.0","Tissue RNA - spinal cord [nTPM]":"15.3","Tissue RNA - spleen [nTPM]":"17.4","Tissue RNA - stomach 1 [nTPM]":"33.1","Tissue RNA - testis [nTPM]":"19.7","Tissue RNA - thalamus [nTPM]":"25.1","Tissue RNA - thymus [nTPM]":"42.8","Tissue RNA - thyroid gland [nTPM]":"19.0","Tissue RNA - tongue [nTPM]":"27.4","Tissue RNA - tonsil [nTPM]":"11.2","Tissue RNA - urinary bladder [nTPM]":"33.4","Tissue RNA - vagina [nTPM]":"19.5","Tissue RNA - white matter [nTPM]":"15.5","Cell RNA - A-431 [nTPM]":"79.5","Cell RNA - A549 [nTPM]":"103.7","Cell RNA - AF22 [nTPM]":"59.9","Cell RNA - AN3-CA [nTPM]":"71.4","Cell RNA - ASC diff [nTPM]":"112.4","Cell RNA - ASC TERT1 [nTPM]":"95.3","Cell RNA - BEWO [nTPM]":"122.8","Cell RNA - BJ [nTPM]":"146.3","Cell RNA - BJ hTERT+ [nTPM]":"90.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"58.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"55.6","Cell RNA - CACO-2 [nTPM]":"45.2","Cell RNA - CAPAN-2 [nTPM]":"146.5","Cell RNA - Daudi [nTPM]":"20.0","Cell RNA - EFO-21 [nTPM]":"106.2","Cell RNA - fHDF\/TERT166 [nTPM]":"77.7","Cell RNA - GAMG [nTPM]":"135.9","Cell RNA - HaCaT [nTPM]":"150.7","Cell RNA - HAP1 [nTPM]":"39.9","Cell RNA - HBEC3-KT [nTPM]":"123.0","Cell RNA - HBF TERT88 [nTPM]":"48.6","Cell RNA - HDLM-2 [nTPM]":"200.1","Cell RNA - HEK 293 [nTPM]":"52.0","Cell RNA - HEL [nTPM]":"60.7","Cell RNA - HeLa [nTPM]":"217.2","Cell RNA - Hep G2 [nTPM]":"50.9","Cell RNA - HHSteC [nTPM]":"60.9","Cell RNA - HL-60 [nTPM]":"23.4","Cell RNA - HMC-1 [nTPM]":"114.8","Cell RNA - HSkMC [nTPM]":"136.9","Cell RNA - hTCEpi [nTPM]":"59.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"78.0","Cell RNA - hTERT-HME1 [nTPM]":"30.9","Cell RNA - hTERT-RPE1 [nTPM]":"127.3","Cell RNA - HUVEC TERT2 [nTPM]":"69.2","Cell RNA - JURKAT [nTPM]":"110.1","Cell RNA - K-562 [nTPM]":"77.0","Cell RNA - Karpas-707 [nTPM]":"29.6","Cell RNA - LHCN-M2 [nTPM]":"65.6","Cell RNA - MCF7 [nTPM]":"21.8","Cell RNA - MOLT-4 [nTPM]":"122.3","Cell RNA - NB-4 [nTPM]":"23.9","Cell RNA - NTERA-2 [nTPM]":"82.1","Cell RNA - OE19 [nTPM]":"52.8","Cell RNA - PC-3 [nTPM]":"97.7","Cell RNA - REH [nTPM]":"134.3","Cell RNA - RH-30 [nTPM]":"85.5","Cell RNA - RPMI-8226 [nTPM]":"61.7","Cell RNA - RPTEC TERT1 [nTPM]":"57.4","Cell RNA - RT4 [nTPM]":"92.9","Cell RNA - SCLC-21H [nTPM]":"18.9","Cell RNA - SH-SY5Y [nTPM]":"70.1","Cell RNA - SiHa [nTPM]":"148.4","Cell RNA - SK-BR-3 [nTPM]":"7.9","Cell RNA - SK-MEL-30 [nTPM]":"91.0","Cell RNA - SuSa [nTPM]":"31.7","Cell RNA - T-47d [nTPM]":"46.5","Cell RNA - THP-1 [nTPM]":"43.5","Cell RNA - TIME [nTPM]":"165.3","Cell RNA - U-138 MG [nTPM]":"56.7","Cell RNA - U-2 OS [nTPM]":"107.9","Cell RNA - U-2197 [nTPM]":"129.5","Cell RNA - U-251 MG [nTPM]":"118.0","Cell RNA - U-266\/70 [nTPM]":"97.9","Cell RNA - U-266\/84 [nTPM]":"60.3","Cell RNA - U-698 [nTPM]":"44.4","Cell RNA - U-87 MG [nTPM]":"146.1","Cell RNA - U-937 [nTPM]":"46.3","Cell RNA - WM-115 [nTPM]":"429.7","Blood RNA - basophil [nTPM]":"1.5","Blood RNA - classical monocyte [nTPM]":"10.7","Blood RNA - eosinophil [nTPM]":"3.6","Blood RNA - gdT-cell [nTPM]":"4.4","Blood RNA - intermediate monocyte [nTPM]":"9.3","Blood RNA - MAIT T-cell [nTPM]":"3.2","Blood RNA - memory B-cell [nTPM]":"3.4","Blood RNA - memory CD4 T-cell [nTPM]":"2.6","Blood RNA - memory CD8 T-cell [nTPM]":"4.5","Blood RNA - myeloid DC [nTPM]":"7.8","Blood RNA - naive B-cell [nTPM]":"5.8","Blood RNA - naive CD4 T-cell [nTPM]":"2.5","Blood RNA - naive CD8 T-cell [nTPM]":"5.0","Blood RNA - neutrophil [nTPM]":"3.2","Blood RNA - NK-cell [nTPM]":"2.8","Blood RNA - non-classical monocyte [nTPM]":"10.2","Blood RNA - plasmacytoid DC [nTPM]":"13.2","Blood RNA - T-reg [nTPM]":"3.3","Blood RNA - total PBMC [nTPM]":"7.7","Brain RNA - amygdala [nTPM]":"17.0","Brain RNA - basal ganglia [nTPM]":"19.9","Brain RNA - cerebellum [nTPM]":"15.2","Brain RNA - cerebral cortex [nTPM]":"16.7","Brain RNA - hippocampal formation [nTPM]":"15.8","Brain RNA - hypothalamus [nTPM]":"18.6","Brain RNA - medulla oblongata [nTPM]":"23.0","Brain RNA - midbrain [nTPM]":"19.5","Brain RNA - pons [nTPM]":"18.3","Brain RNA - spinal cord [nTPM]":"15.3","Brain RNA - thalamus [nTPM]":"25.1","Brain RNA - white matter [nTPM]":"15.5","Single Cell Type RNA - Adipocytes [nTPM]":"18.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.3","Single Cell Type RNA - Astrocytes [nTPM]":"71.5","Single Cell Type RNA - B-cells [nTPM]":"32.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"52.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"20.5","Single Cell Type RNA - Bipolar cells [nTPM]":"30.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"30.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.3","Single Cell Type RNA - dendritic cells [nTPM]":"21.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"49.7","Single Cell Type RNA - Early spermatids [nTPM]":"47.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.4","Single Cell Type RNA - Endothelial cells [nTPM]":"17.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.8","Single Cell Type RNA - Erythroid cells [nTPM]":"27.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"67.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"133.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"123.4","Single Cell Type RNA - Fibroblasts [nTPM]":"36.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.5","Single Cell Type RNA - granulocytes [nTPM]":"13.3","Single Cell Type RNA - Granulosa cells [nTPM]":"20.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.6","Single Cell Type RNA - Hepatocytes [nTPM]":"98.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.9","Single Cell Type RNA - Horizontal cells [nTPM]":"28.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"82.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.9","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"42.4","Single Cell Type RNA - Langerhans cells [nTPM]":"9.7","Single Cell Type RNA - Late spermatids [nTPM]":"24.6","Single Cell Type RNA - Leydig cells [nTPM]":"35.8","Single Cell Type RNA - Macrophages [nTPM]":"28.9","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"106.8","Single Cell Type RNA - monocytes [nTPM]":"44.0","Single Cell Type RNA - Muller glia cells [nTPM]":"10.9","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"72.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"44.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"88.5","Single Cell Type RNA - Paneth cells [nTPM]":"21.6","Single Cell Type RNA - Peritubular cells [nTPM]":"29.3","Single Cell Type RNA - Plasma cells [nTPM]":"109.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"73.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"33.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"25.4","Single Cell Type RNA - Spermatocytes [nTPM]":"3.4","Single Cell Type RNA - Spermatogonia [nTPM]":"14.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.6","Single Cell Type RNA - T-cells [nTPM]":"21.2","Single Cell Type RNA - Theca cells [nTPM]":"32.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.6","Single Cell Type RNA - Urothelial cells [nTPM]":"29.9"},{"Gene":"GALNT3","Gene synonym":["GalNAc-T3","HFTC","HHS"],"Ensembl":"ENSG00000115339","Gene description":"Polypeptide N-acetylgalactosaminyltransferase 3","Uniprot":["Q14435"],"Chromosome":"2","Position":"165747588-165794659","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"stomach 1":"77.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Intestinal goblet cells":"152.8","Pancreatic endocrine cells":"188.1","Prostatic glandular cells":"155.7","Urothelial cells":"274.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"50.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"85.4","HaCaT":"108.3","HBEC3-KT":"69.2","hTCEpi":"88.2","OE19":"201.1"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007613"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"440000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA007613":"AB_1078941"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.08e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.10e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.5","Tissue RNA - adrenal gland [nTPM]":"1.7","Tissue RNA - amygdala [nTPM]":"1.7","Tissue RNA - appendix [nTPM]":"8.4","Tissue RNA - basal ganglia [nTPM]":"2.1","Tissue RNA - bone marrow [nTPM]":"54.0","Tissue RNA - breast [nTPM]":"26.0","Tissue RNA - cerebellum [nTPM]":"2.7","Tissue RNA - cerebral cortex [nTPM]":"1.8","Tissue RNA - cervix [nTPM]":"29.3","Tissue RNA - choroid plexus [nTPM]":"4.3","Tissue RNA - colon [nTPM]":"48.9","Tissue RNA - duodenum [nTPM]":"43.5","Tissue RNA - endometrium 1 [nTPM]":"5.2","Tissue RNA - epididymis [nTPM]":"9.3","Tissue RNA - esophagus [nTPM]":"27.4","Tissue RNA - fallopian tube [nTPM]":"38.8","Tissue RNA - gallbladder [nTPM]":"32.2","Tissue RNA - heart muscle [nTPM]":"0.6","Tissue RNA - hippocampal formation [nTPM]":"1.8","Tissue RNA - hypothalamus [nTPM]":"3.4","Tissue RNA - kidney [nTPM]":"10.9","Tissue RNA - liver [nTPM]":"2.4","Tissue RNA - lung [nTPM]":"14.0","Tissue RNA - lymph node [nTPM]":"3.7","Tissue RNA - medulla oblongata [nTPM]":"4.5","Tissue RNA - midbrain [nTPM]":"5.2","Tissue RNA - ovary [nTPM]":"6.8","Tissue RNA - pancreas [nTPM]":"26.2","Tissue RNA - parathyroid gland [nTPM]":"6.9","Tissue RNA - pituitary gland [nTPM]":"9.8","Tissue RNA - placenta [nTPM]":"6.4","Tissue RNA - pons [nTPM]":"3.3","Tissue RNA - prostate [nTPM]":"25.2","Tissue RNA - rectum [nTPM]":"53.2","Tissue RNA - retina [nTPM]":"3.7","Tissue RNA - salivary gland [nTPM]":"55.3","Tissue RNA - seminal vesicle [nTPM]":"8.2","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"15.3","Tissue RNA - small intestine [nTPM]":"39.5","Tissue RNA - smooth muscle [nTPM]":"2.5","Tissue RNA - spinal cord [nTPM]":"7.0","Tissue RNA - spleen [nTPM]":"20.1","Tissue RNA - stomach 1 [nTPM]":"77.3","Tissue RNA - testis [nTPM]":"25.8","Tissue RNA - thalamus [nTPM]":"1.9","Tissue RNA - thymus [nTPM]":"3.3","Tissue RNA - thyroid gland [nTPM]":"25.4","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"12.3","Tissue RNA - urinary bladder [nTPM]":"17.3","Tissue RNA - vagina [nTPM]":"12.6","Tissue RNA - white matter [nTPM]":"5.4","Cell RNA - A-431 [nTPM]":"61.5","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"2.6","Cell RNA - BEWO [nTPM]":"43.0","Cell RNA - BJ [nTPM]":"18.3","Cell RNA - BJ hTERT+ [nTPM]":"7.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.0","Cell RNA - CACO-2 [nTPM]":"32.0","Cell RNA - CAPAN-2 [nTPM]":"85.4","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"108.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"69.2","Cell RNA - HBF TERT88 [nTPM]":"13.5","Cell RNA - HDLM-2 [nTPM]":"1.3","Cell RNA - HEK 293 [nTPM]":"13.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"14.9","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"14.5","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"0.5","Cell RNA - hTCEpi [nTPM]":"88.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"30.3","Cell RNA - hTERT-RPE1 [nTPM]":"2.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"2.9","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"55.0","Cell RNA - LHCN-M2 [nTPM]":"5.0","Cell RNA - MCF7 [nTPM]":"42.7","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"5.6","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"201.1","Cell RNA - PC-3 [nTPM]":"7.8","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.7","Cell RNA - RPTEC TERT1 [nTPM]":"17.8","Cell RNA - RT4 [nTPM]":"42.0","Cell RNA - SCLC-21H [nTPM]":"6.5","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"49.6","Cell RNA - SK-MEL-30 [nTPM]":"16.8","Cell RNA - SuSa [nTPM]":"1.9","Cell RNA - T-47d [nTPM]":"21.7","Cell RNA - THP-1 [nTPM]":"0.9","Cell RNA - TIME [nTPM]":"0.5","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"1.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"34.4","Cell RNA - U-266\/84 [nTPM]":"16.3","Cell RNA - U-698 [nTPM]":"1.3","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"14.0","Cell RNA - WM-115 [nTPM]":"0.6","Blood RNA - basophil [nTPM]":"50.5","Blood RNA - classical monocyte [nTPM]":"6.8","Blood RNA - eosinophil [nTPM]":"32.2","Blood RNA - gdT-cell [nTPM]":"10.2","Blood RNA - intermediate monocyte [nTPM]":"9.0","Blood RNA - MAIT T-cell [nTPM]":"7.5","Blood RNA - memory B-cell [nTPM]":"6.6","Blood RNA - memory CD4 T-cell [nTPM]":"3.1","Blood RNA - memory CD8 T-cell [nTPM]":"5.8","Blood RNA - myeloid DC [nTPM]":"11.4","Blood RNA - naive B-cell [nTPM]":"6.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"3.4","Blood RNA - neutrophil [nTPM]":"25.2","Blood RNA - NK-cell [nTPM]":"10.6","Blood RNA - non-classical monocyte [nTPM]":"13.8","Blood RNA - plasmacytoid DC [nTPM]":"17.3","Blood RNA - T-reg [nTPM]":"5.6","Blood RNA - total PBMC [nTPM]":"6.2","Brain RNA - amygdala [nTPM]":"1.7","Brain RNA - basal ganglia [nTPM]":"2.1","Brain RNA - cerebellum [nTPM]":"2.7","Brain RNA - cerebral cortex [nTPM]":"1.8","Brain RNA - hippocampal formation [nTPM]":"1.8","Brain RNA - hypothalamus [nTPM]":"3.4","Brain RNA - medulla oblongata [nTPM]":"4.5","Brain RNA - midbrain [nTPM]":"5.2","Brain RNA - pons [nTPM]":"3.3","Brain RNA - spinal cord [nTPM]":"7.0","Brain RNA - thalamus [nTPM]":"1.9","Brain RNA - white matter [nTPM]":"5.4","Single Cell Type RNA - Adipocytes [nTPM]":"1.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"34.4","Single Cell Type RNA - Astrocytes [nTPM]":"7.8","Single Cell Type RNA - B-cells [nTPM]":"13.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"38.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"107.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"36.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"29.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"45.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"26.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"35.8","Single Cell Type RNA - Club cells [nTPM]":"45.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"66.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.5","Single Cell Type RNA - dendritic cells [nTPM]":"37.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"68.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"70.2","Single Cell Type RNA - Early spermatids [nTPM]":"127.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"91.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.2","Single Cell Type RNA - Endothelial cells [nTPM]":"2.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"23.4","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"113.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"22.5","Single Cell Type RNA - Fibroblasts [nTPM]":"2.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"102.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"70.5","Single Cell Type RNA - granulocytes [nTPM]":"45.7","Single Cell Type RNA - Granulosa cells [nTPM]":"0.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"152.8","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"12.4","Single Cell Type RNA - Late spermatids [nTPM]":"14.1","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"8.3","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"7.5","Single Cell Type RNA - Muller glia cells [nTPM]":"16.1","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"27.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"188.1","Single Cell Type RNA - Paneth cells [nTPM]":"46.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"29.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"155.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"32.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"89.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.3","Single Cell Type RNA - Spermatocytes [nTPM]":"71.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"42.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"41.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.2","Single Cell Type RNA - T-cells [nTPM]":"14.4","Single Cell Type RNA - Theca cells [nTPM]":"1.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"61.8","Single Cell Type RNA - Urothelial cells [nTPM]":"274.4"},{"Gene":"GALT","Gene synonym":[],"Ensembl":"ENSG00000213930","Gene description":"Galactose-1-phosphate uridylyltransferase","Uniprot":["P07902"],"Chromosome":"9","Position":"34638133-34651035","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism","Galactose metabolism"],"Molecular function":["Nucleotidyltransferase","Transferase"],"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"50.0"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004868","HPA005729"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"260000","Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA004868":"AB_1079130","HPA005729":"AB_1079131"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.11e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.25e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.7","Tissue RNA - adrenal gland [nTPM]":"14.0","Tissue RNA - amygdala [nTPM]":"5.3","Tissue RNA - appendix [nTPM]":"6.7","Tissue RNA - basal ganglia [nTPM]":"5.9","Tissue RNA - bone marrow [nTPM]":"8.1","Tissue RNA - breast [nTPM]":"6.3","Tissue RNA - cerebellum [nTPM]":"5.5","Tissue RNA - cerebral cortex [nTPM]":"6.5","Tissue RNA - cervix [nTPM]":"6.9","Tissue RNA - choroid plexus [nTPM]":"4.6","Tissue RNA - colon [nTPM]":"8.5","Tissue RNA - duodenum [nTPM]":"18.3","Tissue RNA - endometrium 1 [nTPM]":"6.9","Tissue RNA - epididymis [nTPM]":"5.3","Tissue RNA - esophagus [nTPM]":"5.3","Tissue RNA - fallopian tube [nTPM]":"7.8","Tissue RNA - gallbladder [nTPM]":"6.8","Tissue RNA - heart muscle [nTPM]":"10.4","Tissue RNA - hippocampal formation [nTPM]":"5.2","Tissue RNA - hypothalamus [nTPM]":"6.3","Tissue RNA - kidney [nTPM]":"10.0","Tissue RNA - liver [nTPM]":"50.0","Tissue RNA - lung [nTPM]":"6.6","Tissue RNA - lymph node [nTPM]":"12.0","Tissue RNA - medulla oblongata [nTPM]":"5.5","Tissue RNA - midbrain [nTPM]":"5.7","Tissue RNA - ovary [nTPM]":"8.2","Tissue RNA - pancreas [nTPM]":"7.5","Tissue RNA - parathyroid gland [nTPM]":"13.0","Tissue RNA - pituitary gland [nTPM]":"6.1","Tissue RNA - placenta [nTPM]":"9.2","Tissue RNA - pons [nTPM]":"5.3","Tissue RNA - prostate [nTPM]":"6.4","Tissue RNA - rectum [nTPM]":"6.7","Tissue RNA - retina [nTPM]":"6.3","Tissue RNA - salivary gland [nTPM]":"12.3","Tissue RNA - seminal vesicle [nTPM]":"7.5","Tissue RNA - skeletal muscle [nTPM]":"10.2","Tissue RNA - skin 1 [nTPM]":"15.2","Tissue RNA - small intestine [nTPM]":"16.5","Tissue RNA - smooth muscle [nTPM]":"4.0","Tissue RNA - spinal cord [nTPM]":"4.5","Tissue RNA - spleen [nTPM]":"9.7","Tissue RNA - stomach 1 [nTPM]":"8.1","Tissue RNA - testis [nTPM]":"2.4","Tissue RNA - thalamus [nTPM]":"6.1","Tissue RNA - thymus [nTPM]":"7.8","Tissue RNA - thyroid gland [nTPM]":"8.2","Tissue RNA - tongue [nTPM]":"7.6","Tissue RNA - tonsil [nTPM]":"7.7","Tissue RNA - urinary bladder [nTPM]":"5.3","Tissue RNA - vagina [nTPM]":"6.1","Tissue RNA - white matter [nTPM]":"4.7","Cell RNA - A-431 [nTPM]":"5.5","Cell RNA - A549 [nTPM]":"7.5","Cell RNA - AF22 [nTPM]":"6.8","Cell RNA - AN3-CA [nTPM]":"2.4","Cell RNA - ASC diff [nTPM]":"9.0","Cell RNA - ASC TERT1 [nTPM]":"9.2","Cell RNA - BEWO [nTPM]":"7.8","Cell RNA - BJ [nTPM]":"4.2","Cell RNA - BJ hTERT+ [nTPM]":"12.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.1","Cell RNA - CACO-2 [nTPM]":"9.5","Cell RNA - CAPAN-2 [nTPM]":"4.8","Cell RNA - Daudi [nTPM]":"6.1","Cell RNA - EFO-21 [nTPM]":"4.2","Cell RNA - fHDF\/TERT166 [nTPM]":"5.2","Cell RNA - GAMG [nTPM]":"1.6","Cell RNA - HaCaT [nTPM]":"2.9","Cell RNA - HAP1 [nTPM]":"1.3","Cell RNA - HBEC3-KT [nTPM]":"11.8","Cell RNA - HBF TERT88 [nTPM]":"0.8","Cell RNA - HDLM-2 [nTPM]":"9.7","Cell RNA - HEK 293 [nTPM]":"4.8","Cell RNA - HEL [nTPM]":"2.5","Cell RNA - HeLa [nTPM]":"14.7","Cell RNA - Hep G2 [nTPM]":"9.8","Cell RNA - HHSteC [nTPM]":"8.7","Cell RNA - HL-60 [nTPM]":"1.4","Cell RNA - HMC-1 [nTPM]":"2.9","Cell RNA - HSkMC [nTPM]":"12.6","Cell RNA - hTCEpi [nTPM]":"7.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.7","Cell RNA - hTERT-HME1 [nTPM]":"3.6","Cell RNA - hTERT-RPE1 [nTPM]":"9.3","Cell RNA - HUVEC TERT2 [nTPM]":"10.6","Cell RNA - JURKAT [nTPM]":"8.3","Cell RNA - K-562 [nTPM]":"2.3","Cell RNA - Karpas-707 [nTPM]":"6.4","Cell RNA - LHCN-M2 [nTPM]":"7.3","Cell RNA - MCF7 [nTPM]":"5.1","Cell RNA - MOLT-4 [nTPM]":"5.4","Cell RNA - NB-4 [nTPM]":"10.3","Cell RNA - NTERA-2 [nTPM]":"2.3","Cell RNA - OE19 [nTPM]":"6.7","Cell RNA - PC-3 [nTPM]":"1.3","Cell RNA - REH [nTPM]":"8.4","Cell RNA - RH-30 [nTPM]":"5.9","Cell RNA - RPMI-8226 [nTPM]":"3.3","Cell RNA - RPTEC TERT1 [nTPM]":"12.5","Cell RNA - RT4 [nTPM]":"7.8","Cell RNA - SCLC-21H [nTPM]":"1.6","Cell RNA - SH-SY5Y [nTPM]":"5.7","Cell RNA - SiHa [nTPM]":"5.0","Cell RNA - SK-BR-3 [nTPM]":"9.8","Cell RNA - SK-MEL-30 [nTPM]":"5.4","Cell RNA - SuSa [nTPM]":"5.0","Cell RNA - T-47d [nTPM]":"9.2","Cell RNA - THP-1 [nTPM]":"8.2","Cell RNA - TIME [nTPM]":"1.6","Cell RNA - U-138 MG [nTPM]":"1.7","Cell RNA - U-2 OS [nTPM]":"3.4","Cell RNA - U-2197 [nTPM]":"3.4","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"3.9","Cell RNA - U-266\/84 [nTPM]":"2.4","Cell RNA - U-698 [nTPM]":"1.3","Cell RNA - U-87 MG [nTPM]":"4.1","Cell RNA - U-937 [nTPM]":"4.4","Cell RNA - WM-115 [nTPM]":"10.8","Blood RNA - basophil [nTPM]":"16.5","Blood RNA - classical monocyte [nTPM]":"23.7","Blood RNA - eosinophil [nTPM]":"11.7","Blood RNA - gdT-cell [nTPM]":"15.4","Blood RNA - intermediate monocyte [nTPM]":"21.5","Blood RNA - MAIT T-cell [nTPM]":"21.3","Blood RNA - memory B-cell [nTPM]":"24.8","Blood RNA - memory CD4 T-cell [nTPM]":"25.2","Blood RNA - memory CD8 T-cell [nTPM]":"21.1","Blood RNA - myeloid DC [nTPM]":"21.5","Blood RNA - naive B-cell [nTPM]":"13.2","Blood RNA - naive CD4 T-cell [nTPM]":"15.3","Blood RNA - naive CD8 T-cell [nTPM]":"14.8","Blood RNA - neutrophil [nTPM]":"4.6","Blood RNA - NK-cell [nTPM]":"29.0","Blood RNA - non-classical monocyte [nTPM]":"20.4","Blood RNA - plasmacytoid DC [nTPM]":"18.2","Blood RNA - T-reg [nTPM]":"30.0","Blood RNA - total PBMC [nTPM]":"17.6","Brain RNA - amygdala [nTPM]":"5.3","Brain RNA - basal ganglia [nTPM]":"5.9","Brain RNA - cerebellum [nTPM]":"5.5","Brain RNA - cerebral cortex [nTPM]":"6.5","Brain RNA - hippocampal formation [nTPM]":"5.2","Brain RNA - hypothalamus [nTPM]":"6.3","Brain RNA - medulla oblongata [nTPM]":"5.5","Brain RNA - midbrain [nTPM]":"5.7","Brain RNA - pons [nTPM]":"5.3","Brain RNA - spinal cord [nTPM]":"4.5","Brain RNA - thalamus [nTPM]":"6.1","Brain RNA - white matter [nTPM]":"4.7","Single Cell Type RNA - Adipocytes [nTPM]":"12.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.2","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"19.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"21.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"19.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.4","Single Cell Type RNA - Bipolar cells [nTPM]":"44.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"15.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"47.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"72.5","Single Cell Type RNA - dendritic cells [nTPM]":"13.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"29.4","Single Cell Type RNA - Ductal cells [nTPM]":"18.3","Single Cell Type RNA - Early spermatids [nTPM]":"7.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.8","Single Cell Type RNA - Endothelial cells [nTPM]":"14.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.3","Single Cell Type RNA - Erythroid cells [nTPM]":"13.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"36.3","Single Cell Type RNA - Fibroblasts [nTPM]":"18.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.0","Single Cell Type RNA - granulocytes [nTPM]":"20.3","Single Cell Type RNA - Granulosa cells [nTPM]":"24.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.6","Single Cell Type RNA - Hepatocytes [nTPM]":"69.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.1","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.0","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"15.5","Single Cell Type RNA - Langerhans cells [nTPM]":"8.7","Single Cell Type RNA - Late spermatids [nTPM]":"36.8","Single Cell Type RNA - Leydig cells [nTPM]":"18.3","Single Cell Type RNA - Macrophages [nTPM]":"12.4","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"15.9","Single Cell Type RNA - Muller glia cells [nTPM]":"18.7","Single Cell Type RNA - NK-cells [nTPM]":"34.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.9","Single Cell Type RNA - Paneth cells [nTPM]":"37.5","Single Cell Type RNA - Peritubular cells [nTPM]":"13.9","Single Cell Type RNA - Plasma cells [nTPM]":"10.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"67.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"46.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"38.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.2","Single Cell Type RNA - Spermatocytes [nTPM]":"4.8","Single Cell Type RNA - Spermatogonia [nTPM]":"6.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"59.1","Single Cell Type RNA - T-cells [nTPM]":"25.5","Single Cell Type RNA - Theca cells [nTPM]":"27.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.4","Single Cell Type RNA - Urothelial cells [nTPM]":"9.2"},{"Gene":"GARS1","Gene synonym":["CMT2D","DSMAV","GARS","GlyRS","SMAD1"],"Ensembl":"ENSG00000106105","Gene description":"Glycyl-tRNA synthetase 1","Uniprot":["P41250"],"Chromosome":"7","Position":"30580533-30634033","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Hydrolase","Ligase","Transferase"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"34.1","Cytotrophoblasts":"47.0","Extravillous trophoblasts":"70.0","Hofbauer cells":"44.3","Syncytiotrophoblasts":"39.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017896","HPA019097"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"560000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA017896":"AB_1849478","HPA019097":"AB_1849480"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.02e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.48e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.95e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.31e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.70e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.04e-5"},"Tissue RNA - adipose tissue [nTPM]":"34.2","Tissue RNA - adrenal gland [nTPM]":"31.0","Tissue RNA - amygdala [nTPM]":"33.3","Tissue RNA - appendix [nTPM]":"43.3","Tissue RNA - basal ganglia [nTPM]":"36.5","Tissue RNA - bone marrow [nTPM]":"32.0","Tissue RNA - breast [nTPM]":"31.7","Tissue RNA - cerebellum [nTPM]":"34.2","Tissue RNA - cerebral cortex [nTPM]":"46.2","Tissue RNA - cervix [nTPM]":"32.6","Tissue RNA - choroid plexus [nTPM]":"49.9","Tissue RNA - colon [nTPM]":"39.8","Tissue RNA - duodenum [nTPM]":"27.6","Tissue RNA - endometrium 1 [nTPM]":"29.1","Tissue RNA - epididymis [nTPM]":"37.3","Tissue RNA - esophagus [nTPM]":"53.8","Tissue RNA - fallopian tube [nTPM]":"23.3","Tissue RNA - gallbladder [nTPM]":"29.9","Tissue RNA - heart muscle [nTPM]":"32.9","Tissue RNA - hippocampal formation [nTPM]":"38.6","Tissue RNA - hypothalamus [nTPM]":"45.7","Tissue RNA - kidney [nTPM]":"42.7","Tissue RNA - liver [nTPM]":"46.0","Tissue RNA - lung [nTPM]":"34.0","Tissue RNA - lymph node [nTPM]":"47.2","Tissue RNA - medulla oblongata [nTPM]":"38.1","Tissue RNA - midbrain [nTPM]":"34.7","Tissue RNA - ovary [nTPM]":"26.7","Tissue RNA - pancreas [nTPM]":"78.5","Tissue RNA - parathyroid gland [nTPM]":"58.1","Tissue RNA - pituitary gland [nTPM]":"36.5","Tissue RNA - placenta [nTPM]":"39.9","Tissue RNA - pons [nTPM]":"42.0","Tissue RNA - prostate [nTPM]":"26.8","Tissue RNA - rectum [nTPM]":"48.6","Tissue RNA - retina [nTPM]":"46.9","Tissue RNA - salivary gland [nTPM]":"36.1","Tissue RNA - seminal vesicle [nTPM]":"29.3","Tissue RNA - skeletal muscle [nTPM]":"48.1","Tissue RNA - skin 1 [nTPM]":"43.4","Tissue RNA - small intestine [nTPM]":"26.0","Tissue RNA - smooth muscle [nTPM]":"49.8","Tissue RNA - spinal cord [nTPM]":"33.2","Tissue RNA - spleen [nTPM]":"22.3","Tissue RNA - stomach 1 [nTPM]":"47.4","Tissue RNA - testis [nTPM]":"51.5","Tissue RNA - thalamus [nTPM]":"43.4","Tissue RNA - thymus [nTPM]":"40.7","Tissue RNA - thyroid gland [nTPM]":"51.5","Tissue RNA - tongue [nTPM]":"45.0","Tissue RNA - tonsil [nTPM]":"67.3","Tissue RNA - urinary bladder [nTPM]":"54.0","Tissue RNA - vagina [nTPM]":"29.4","Tissue RNA - white matter [nTPM]":"35.2","Cell RNA - A-431 [nTPM]":"231.4","Cell RNA - A549 [nTPM]":"119.8","Cell RNA - AF22 [nTPM]":"103.4","Cell RNA - AN3-CA [nTPM]":"364.5","Cell RNA - ASC diff [nTPM]":"191.9","Cell RNA - ASC TERT1 [nTPM]":"286.8","Cell RNA - BEWO [nTPM]":"172.0","Cell RNA - BJ [nTPM]":"332.4","Cell RNA - BJ hTERT+ [nTPM]":"330.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"184.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"369.8","Cell RNA - CACO-2 [nTPM]":"159.5","Cell RNA - CAPAN-2 [nTPM]":"115.4","Cell RNA - Daudi [nTPM]":"375.9","Cell RNA - EFO-21 [nTPM]":"96.2","Cell RNA - fHDF\/TERT166 [nTPM]":"443.1","Cell RNA - GAMG [nTPM]":"281.6","Cell RNA - HaCaT [nTPM]":"174.5","Cell RNA - HAP1 [nTPM]":"262.6","Cell RNA - HBEC3-KT [nTPM]":"230.2","Cell RNA - HBF TERT88 [nTPM]":"327.7","Cell RNA - HDLM-2 [nTPM]":"92.9","Cell RNA - HEK 293 [nTPM]":"82.5","Cell RNA - HEL [nTPM]":"182.6","Cell RNA - HeLa [nTPM]":"84.8","Cell RNA - Hep G2 [nTPM]":"141.1","Cell RNA - HHSteC [nTPM]":"604.0","Cell RNA - HL-60 [nTPM]":"267.6","Cell RNA - HMC-1 [nTPM]":"149.8","Cell RNA - HSkMC [nTPM]":"272.5","Cell RNA - hTCEpi [nTPM]":"391.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"265.8","Cell RNA - hTERT-HME1 [nTPM]":"304.9","Cell RNA - hTERT-RPE1 [nTPM]":"128.1","Cell RNA - HUVEC TERT2 [nTPM]":"241.6","Cell RNA - JURKAT [nTPM]":"354.1","Cell RNA - K-562 [nTPM]":"350.2","Cell RNA - Karpas-707 [nTPM]":"465.4","Cell RNA - LHCN-M2 [nTPM]":"296.7","Cell RNA - MCF7 [nTPM]":"154.7","Cell RNA - MOLT-4 [nTPM]":"216.8","Cell RNA - NB-4 [nTPM]":"204.3","Cell RNA - NTERA-2 [nTPM]":"259.6","Cell RNA - OE19 [nTPM]":"222.4","Cell RNA - PC-3 [nTPM]":"183.4","Cell RNA - REH [nTPM]":"114.0","Cell RNA - RH-30 [nTPM]":"90.1","Cell RNA - RPMI-8226 [nTPM]":"299.0","Cell RNA - RPTEC TERT1 [nTPM]":"219.5","Cell RNA - RT4 [nTPM]":"109.1","Cell RNA - SCLC-21H [nTPM]":"117.9","Cell RNA - SH-SY5Y [nTPM]":"177.4","Cell RNA - SiHa [nTPM]":"88.1","Cell RNA - SK-BR-3 [nTPM]":"261.5","Cell RNA - SK-MEL-30 [nTPM]":"509.2","Cell RNA - SuSa [nTPM]":"182.8","Cell RNA - T-47d [nTPM]":"225.3","Cell RNA - THP-1 [nTPM]":"409.3","Cell RNA - TIME [nTPM]":"208.2","Cell RNA - U-138 MG [nTPM]":"82.2","Cell RNA - U-2 OS [nTPM]":"262.9","Cell RNA - U-2197 [nTPM]":"164.9","Cell RNA - U-251 MG [nTPM]":"217.9","Cell RNA - U-266\/70 [nTPM]":"403.8","Cell RNA - U-266\/84 [nTPM]":"390.8","Cell RNA - U-698 [nTPM]":"445.9","Cell RNA - U-87 MG [nTPM]":"289.4","Cell RNA - U-937 [nTPM]":"398.8","Cell RNA - WM-115 [nTPM]":"392.9","Blood RNA - basophil [nTPM]":"40.0","Blood RNA - classical monocyte [nTPM]":"27.0","Blood RNA - eosinophil [nTPM]":"24.1","Blood RNA - gdT-cell [nTPM]":"22.9","Blood RNA - intermediate monocyte [nTPM]":"35.8","Blood RNA - MAIT T-cell [nTPM]":"27.4","Blood RNA - memory B-cell [nTPM]":"21.0","Blood RNA - memory CD4 T-cell [nTPM]":"26.0","Blood RNA - memory CD8 T-cell [nTPM]":"28.8","Blood RNA - myeloid DC [nTPM]":"35.8","Blood RNA - naive B-cell [nTPM]":"16.3","Blood RNA - naive CD4 T-cell [nTPM]":"25.2","Blood RNA - naive CD8 T-cell [nTPM]":"30.2","Blood RNA - neutrophil [nTPM]":"5.2","Blood RNA - NK-cell [nTPM]":"20.9","Blood RNA - non-classical monocyte [nTPM]":"41.7","Blood RNA - plasmacytoid DC [nTPM]":"18.5","Blood RNA - T-reg [nTPM]":"31.9","Blood RNA - total PBMC [nTPM]":"23.9","Brain RNA - amygdala [nTPM]":"33.3","Brain RNA - basal ganglia [nTPM]":"36.5","Brain RNA - cerebellum [nTPM]":"34.2","Brain RNA - cerebral cortex [nTPM]":"46.2","Brain RNA - hippocampal formation [nTPM]":"38.6","Brain RNA - hypothalamus [nTPM]":"45.7","Brain RNA - medulla oblongata [nTPM]":"38.1","Brain RNA - midbrain [nTPM]":"34.7","Brain RNA - pons [nTPM]":"42.0","Brain RNA - spinal cord [nTPM]":"33.2","Brain RNA - thalamus [nTPM]":"43.4","Brain RNA - white matter [nTPM]":"35.2","Single Cell Type RNA - Adipocytes [nTPM]":"10.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"34.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"47.0","Single Cell Type RNA - dendritic cells [nTPM]":"10.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"3.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"70.0","Single Cell Type RNA - Fibroblasts [nTPM]":"13.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"44.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"2.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"5.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"39.8","Single Cell Type RNA - T-cells [nTPM]":"2.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"GATM","Gene synonym":["AGAT"],"Ensembl":"ENSG00000171766","Gene description":"Glycine amidinotransferase","Uniprot":["P50440"],"Chromosome":"15","Position":"45361124-45402327","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"kidney":"2099.3","liver":"2804.2","pancreas":"2935.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Hepatocytes":"1495.2","Proximal tubular cells":"3703.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"135.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"memory B-cell":"11.0","myeloid DC":"6.6","naive B-cell":"5.4","plasmacytoid DC":"6.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"11.0","dendritic cells":"6.8"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"RH-30":"210.1","RT4":"55.8","U-266\/70":"126.3","U-266\/84":"165.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026077"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"600000","Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA026077":"AB_1849528"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.38e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Tissue RNA - adipose tissue [nTPM]":"14.4","Tissue RNA - adrenal gland [nTPM]":"21.4","Tissue RNA - amygdala [nTPM]":"133.9","Tissue RNA - appendix [nTPM]":"12.4","Tissue RNA - basal ganglia [nTPM]":"138.4","Tissue RNA - bone marrow [nTPM]":"1.8","Tissue RNA - breast [nTPM]":"25.4","Tissue RNA - cerebellum [nTPM]":"152.5","Tissue RNA - cerebral cortex [nTPM]":"216.5","Tissue RNA - cervix [nTPM]":"9.9","Tissue RNA - choroid plexus [nTPM]":"94.3","Tissue RNA - colon [nTPM]":"19.6","Tissue RNA - duodenum [nTPM]":"175.5","Tissue RNA - endometrium 1 [nTPM]":"8.4","Tissue RNA - epididymis [nTPM]":"10.5","Tissue RNA - esophagus [nTPM]":"25.1","Tissue RNA - fallopian tube [nTPM]":"11.6","Tissue RNA - gallbladder [nTPM]":"47.7","Tissue RNA - heart muscle [nTPM]":"57.2","Tissue RNA - hippocampal formation [nTPM]":"131.1","Tissue RNA - hypothalamus [nTPM]":"140.9","Tissue RNA - kidney [nTPM]":"2099.3","Tissue RNA - liver [nTPM]":"2804.2","Tissue RNA - lung [nTPM]":"7.3","Tissue RNA - lymph node [nTPM]":"18.4","Tissue RNA - medulla oblongata [nTPM]":"148.0","Tissue RNA - midbrain [nTPM]":"135.4","Tissue RNA - ovary [nTPM]":"165.2","Tissue RNA - pancreas [nTPM]":"2935.3","Tissue RNA - parathyroid gland [nTPM]":"2.7","Tissue RNA - pituitary gland [nTPM]":"8.3","Tissue RNA - placenta [nTPM]":"74.7","Tissue RNA - pons [nTPM]":"153.4","Tissue RNA - prostate [nTPM]":"12.4","Tissue RNA - rectum [nTPM]":"11.5","Tissue RNA - retina [nTPM]":"7.5","Tissue RNA - salivary gland [nTPM]":"57.5","Tissue RNA - seminal vesicle [nTPM]":"15.1","Tissue RNA - skeletal muscle [nTPM]":"142.5","Tissue RNA - skin 1 [nTPM]":"137.6","Tissue RNA - small intestine [nTPM]":"110.2","Tissue RNA - smooth muscle [nTPM]":"14.5","Tissue RNA - spinal cord [nTPM]":"149.2","Tissue RNA - spleen [nTPM]":"33.6","Tissue RNA - stomach 1 [nTPM]":"99.2","Tissue RNA - testis [nTPM]":"78.2","Tissue RNA - thalamus [nTPM]":"140.4","Tissue RNA - thymus [nTPM]":"12.6","Tissue RNA - thyroid gland [nTPM]":"63.0","Tissue RNA - tongue [nTPM]":"46.9","Tissue RNA - tonsil [nTPM]":"29.7","Tissue RNA - urinary bladder [nTPM]":"18.0","Tissue RNA - vagina [nTPM]":"15.5","Tissue RNA - white matter [nTPM]":"181.2","Cell RNA - A-431 [nTPM]":"12.9","Cell RNA - A549 [nTPM]":"6.5","Cell RNA - AF22 [nTPM]":"4.4","Cell RNA - AN3-CA [nTPM]":"0.6","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"0.8","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"1.4","Cell RNA - CAPAN-2 [nTPM]":"21.4","Cell RNA - Daudi [nTPM]":"34.4","Cell RNA - EFO-21 [nTPM]":"1.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"5.7","Cell RNA - HaCaT [nTPM]":"2.2","Cell RNA - HAP1 [nTPM]":"17.0","Cell RNA - HBEC3-KT [nTPM]":"0.6","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"1.9","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"2.8","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"0.8","Cell RNA - HL-60 [nTPM]":"20.7","Cell RNA - HMC-1 [nTPM]":"2.6","Cell RNA - HSkMC [nTPM]":"0.8","Cell RNA - hTCEpi [nTPM]":"0.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.4","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"7.8","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.6","Cell RNA - MOLT-4 [nTPM]":"2.2","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"11.2","Cell RNA - OE19 [nTPM]":"31.3","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.5","Cell RNA - RH-30 [nTPM]":"210.1","Cell RNA - RPMI-8226 [nTPM]":"1.5","Cell RNA - RPTEC TERT1 [nTPM]":"3.5","Cell RNA - RT4 [nTPM]":"55.8","Cell RNA - SCLC-21H [nTPM]":"23.5","Cell RNA - SH-SY5Y [nTPM]":"4.1","Cell RNA - SiHa [nTPM]":"6.9","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"1.2","Cell RNA - SuSa [nTPM]":"2.1","Cell RNA - T-47d [nTPM]":"2.9","Cell RNA - THP-1 [nTPM]":"23.7","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"6.3","Cell RNA - U-266\/70 [nTPM]":"126.3","Cell RNA - U-266\/84 [nTPM]":"165.5","Cell RNA - U-698 [nTPM]":"0.8","Cell RNA - U-87 MG [nTPM]":"1.6","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"1.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"1.6","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"11.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"6.6","Blood RNA - naive B-cell [nTPM]":"5.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.4","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"6.8","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"133.9","Brain RNA - basal ganglia [nTPM]":"138.4","Brain RNA - cerebellum [nTPM]":"152.5","Brain RNA - cerebral cortex [nTPM]":"216.5","Brain RNA - hippocampal formation [nTPM]":"131.1","Brain RNA - hypothalamus [nTPM]":"140.9","Brain RNA - medulla oblongata [nTPM]":"148.0","Brain RNA - midbrain [nTPM]":"135.4","Brain RNA - pons [nTPM]":"153.4","Brain RNA - spinal cord [nTPM]":"149.2","Brain RNA - thalamus [nTPM]":"140.4","Brain RNA - white matter [nTPM]":"181.2","Single Cell Type RNA - Adipocytes [nTPM]":"2.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"67.3","Single Cell Type RNA - B-cells [nTPM]":"42.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"54.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"8.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"35.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"228.8","Single Cell Type RNA - Club cells [nTPM]":"5.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"71.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"295.4","Single Cell Type RNA - Ductal cells [nTPM]":"58.2","Single Cell Type RNA - Early spermatids [nTPM]":"8.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"7.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"29.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"290.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.2","Single Cell Type RNA - Fibroblasts [nTPM]":"19.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"69.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.7","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"219.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.9","Single Cell Type RNA - Hepatocytes [nTPM]":"1495.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"89.6","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.1","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"80.3","Single Cell Type RNA - Langerhans cells [nTPM]":"80.3","Single Cell Type RNA - Late spermatids [nTPM]":"18.3","Single Cell Type RNA - Leydig cells [nTPM]":"4.4","Single Cell Type RNA - Macrophages [nTPM]":"50.6","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"3.1","Single Cell Type RNA - Muller glia cells [nTPM]":"19.1","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"57.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"196.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"97.3","Single Cell Type RNA - Paneth cells [nTPM]":"3.9","Single Cell Type RNA - Peritubular cells [nTPM]":"3.4","Single Cell Type RNA - Plasma cells [nTPM]":"7.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"98.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3703.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"38.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.8","Single Cell Type RNA - Spermatocytes [nTPM]":"22.0","Single Cell Type RNA - Spermatogonia [nTPM]":"9.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"133.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.8","Single Cell Type RNA - T-cells [nTPM]":"17.6","Single Cell Type RNA - Theca cells [nTPM]":"4.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.4","Single Cell Type RNA - Urothelial cells [nTPM]":"20.4"},{"Gene":"GBA","Gene synonym":["GBA1","GLUC"],"Ensembl":"ENSG00000177628","Gene description":"Glucosylceramidase beta","Uniprot":["P04062"],"Chromosome":"1","Position":"155234452-155244699","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Sphingolipid metabolism","Steroid metabolism","Sterol metabolism"],"Molecular function":["Glycosidase","Glycosyltransferase","Hydrolase","Transferase"],"Disease involvement":["Disease variant","Gaucher disease","Ichthyosis","Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"65.2","Syncytiotrophoblasts":"59.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006667","CAB037171","CAB037289"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"470000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB037171":"AB_1078958","CAB037289":"AB_1078957","HPA006667":"AB_1078979"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Tissue RNA - adipose tissue [nTPM]":"23.9","Tissue RNA - adrenal gland [nTPM]":"37.9","Tissue RNA - amygdala [nTPM]":"22.5","Tissue RNA - appendix [nTPM]":"24.8","Tissue RNA - basal ganglia [nTPM]":"24.4","Tissue RNA - bone marrow [nTPM]":"41.7","Tissue RNA - breast [nTPM]":"25.1","Tissue RNA - cerebellum [nTPM]":"25.9","Tissue RNA - cerebral cortex [nTPM]":"24.3","Tissue RNA - cervix [nTPM]":"26.7","Tissue RNA - choroid plexus [nTPM]":"27.4","Tissue RNA - colon [nTPM]":"35.1","Tissue RNA - duodenum [nTPM]":"23.9","Tissue RNA - endometrium 1 [nTPM]":"22.9","Tissue RNA - epididymis [nTPM]":"50.2","Tissue RNA - esophagus [nTPM]":"27.6","Tissue RNA - fallopian tube [nTPM]":"20.5","Tissue RNA - gallbladder [nTPM]":"28.3","Tissue RNA - heart muscle [nTPM]":"19.1","Tissue RNA - hippocampal formation [nTPM]":"26.1","Tissue RNA - hypothalamus [nTPM]":"27.7","Tissue RNA - kidney [nTPM]":"33.6","Tissue RNA - liver [nTPM]":"33.7","Tissue RNA - lung [nTPM]":"28.3","Tissue RNA - lymph node [nTPM]":"19.9","Tissue RNA - medulla oblongata [nTPM]":"27.3","Tissue RNA - midbrain [nTPM]":"28.0","Tissue RNA - ovary [nTPM]":"16.9","Tissue RNA - pancreas [nTPM]":"33.4","Tissue RNA - parathyroid gland [nTPM]":"103.1","Tissue RNA - pituitary gland [nTPM]":"43.8","Tissue RNA - placenta [nTPM]":"39.2","Tissue RNA - pons [nTPM]":"36.2","Tissue RNA - prostate [nTPM]":"23.3","Tissue RNA - rectum [nTPM]":"39.8","Tissue RNA - retina [nTPM]":"12.4","Tissue RNA - salivary gland [nTPM]":"26.8","Tissue RNA - seminal vesicle [nTPM]":"33.6","Tissue RNA - skeletal muscle [nTPM]":"9.1","Tissue RNA - skin 1 [nTPM]":"33.4","Tissue RNA - small intestine [nTPM]":"22.5","Tissue RNA - smooth muscle [nTPM]":"29.7","Tissue RNA - spinal cord [nTPM]":"25.0","Tissue RNA - spleen [nTPM]":"29.0","Tissue RNA - stomach 1 [nTPM]":"22.7","Tissue RNA - testis [nTPM]":"8.8","Tissue RNA - thalamus [nTPM]":"29.2","Tissue RNA - thymus [nTPM]":"19.7","Tissue RNA - thyroid gland [nTPM]":"37.7","Tissue RNA - tongue [nTPM]":"13.6","Tissue RNA - tonsil [nTPM]":"28.0","Tissue RNA - urinary bladder [nTPM]":"27.1","Tissue RNA - vagina [nTPM]":"21.9","Tissue RNA - white matter [nTPM]":"29.5","Cell RNA - A-431 [nTPM]":"38.0","Cell RNA - A549 [nTPM]":"72.2","Cell RNA - AF22 [nTPM]":"25.1","Cell RNA - AN3-CA [nTPM]":"34.2","Cell RNA - ASC diff [nTPM]":"254.8","Cell RNA - ASC TERT1 [nTPM]":"55.8","Cell RNA - BEWO [nTPM]":"29.3","Cell RNA - BJ [nTPM]":"65.4","Cell RNA - BJ hTERT+ [nTPM]":"230.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"95.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"119.0","Cell RNA - CACO-2 [nTPM]":"43.2","Cell RNA - CAPAN-2 [nTPM]":"135.7","Cell RNA - Daudi [nTPM]":"26.3","Cell RNA - EFO-21 [nTPM]":"70.4","Cell RNA - fHDF\/TERT166 [nTPM]":"153.7","Cell RNA - GAMG [nTPM]":"152.0","Cell RNA - HaCaT [nTPM]":"76.2","Cell RNA - HAP1 [nTPM]":"35.9","Cell RNA - HBEC3-KT [nTPM]":"46.4","Cell RNA - HBF TERT88 [nTPM]":"50.3","Cell RNA - HDLM-2 [nTPM]":"55.5","Cell RNA - HEK 293 [nTPM]":"25.1","Cell RNA - HEL [nTPM]":"21.8","Cell RNA - HeLa [nTPM]":"45.1","Cell RNA - Hep G2 [nTPM]":"23.2","Cell RNA - HHSteC [nTPM]":"73.6","Cell RNA - HL-60 [nTPM]":"25.8","Cell RNA - HMC-1 [nTPM]":"87.0","Cell RNA - HSkMC [nTPM]":"73.4","Cell RNA - hTCEpi [nTPM]":"38.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"199.7","Cell RNA - hTERT-HME1 [nTPM]":"30.2","Cell RNA - hTERT-RPE1 [nTPM]":"100.2","Cell RNA - HUVEC TERT2 [nTPM]":"85.6","Cell RNA - JURKAT [nTPM]":"22.2","Cell RNA - K-562 [nTPM]":"23.4","Cell RNA - Karpas-707 [nTPM]":"42.9","Cell RNA - LHCN-M2 [nTPM]":"113.5","Cell RNA - MCF7 [nTPM]":"82.6","Cell RNA - MOLT-4 [nTPM]":"32.5","Cell RNA - NB-4 [nTPM]":"11.9","Cell RNA - NTERA-2 [nTPM]":"16.3","Cell RNA - OE19 [nTPM]":"61.9","Cell RNA - PC-3 [nTPM]":"51.2","Cell RNA - REH [nTPM]":"26.8","Cell RNA - RH-30 [nTPM]":"41.9","Cell RNA - RPMI-8226 [nTPM]":"108.1","Cell RNA - RPTEC TERT1 [nTPM]":"63.9","Cell RNA - RT4 [nTPM]":"29.0","Cell RNA - SCLC-21H [nTPM]":"23.9","Cell RNA - SH-SY5Y [nTPM]":"33.5","Cell RNA - SiHa [nTPM]":"57.4","Cell RNA - SK-BR-3 [nTPM]":"136.4","Cell RNA - SK-MEL-30 [nTPM]":"145.3","Cell RNA - SuSa [nTPM]":"45.6","Cell RNA - T-47d [nTPM]":"102.6","Cell RNA - THP-1 [nTPM]":"63.3","Cell RNA - TIME [nTPM]":"65.7","Cell RNA - U-138 MG [nTPM]":"71.7","Cell RNA - U-2 OS [nTPM]":"31.7","Cell RNA - U-2197 [nTPM]":"91.9","Cell RNA - U-251 MG [nTPM]":"53.7","Cell RNA - U-266\/70 [nTPM]":"86.2","Cell RNA - U-266\/84 [nTPM]":"78.6","Cell RNA - U-698 [nTPM]":"20.4","Cell RNA - U-87 MG [nTPM]":"126.6","Cell RNA - U-937 [nTPM]":"23.4","Cell RNA - WM-115 [nTPM]":"56.4","Blood RNA - basophil [nTPM]":"21.4","Blood RNA - classical monocyte [nTPM]":"36.0","Blood RNA - eosinophil [nTPM]":"15.3","Blood RNA - gdT-cell [nTPM]":"20.8","Blood RNA - intermediate monocyte [nTPM]":"35.8","Blood RNA - MAIT T-cell [nTPM]":"13.2","Blood RNA - memory B-cell [nTPM]":"11.1","Blood RNA - memory CD4 T-cell [nTPM]":"15.7","Blood RNA - memory CD8 T-cell [nTPM]":"13.8","Blood RNA - myeloid DC [nTPM]":"22.4","Blood RNA - naive B-cell [nTPM]":"7.8","Blood RNA - naive CD4 T-cell [nTPM]":"11.0","Blood RNA - naive CD8 T-cell [nTPM]":"11.7","Blood RNA - neutrophil [nTPM]":"28.9","Blood RNA - NK-cell [nTPM]":"11.6","Blood RNA - non-classical monocyte [nTPM]":"37.2","Blood RNA - plasmacytoid DC [nTPM]":"12.5","Blood RNA - T-reg [nTPM]":"23.4","Blood RNA - total PBMC [nTPM]":"23.3","Brain RNA - amygdala [nTPM]":"22.5","Brain RNA - basal ganglia [nTPM]":"24.4","Brain RNA - cerebellum [nTPM]":"25.9","Brain RNA - cerebral cortex [nTPM]":"24.3","Brain RNA - hippocampal formation [nTPM]":"26.1","Brain RNA - hypothalamus [nTPM]":"27.7","Brain RNA - medulla oblongata [nTPM]":"27.3","Brain RNA - midbrain [nTPM]":"28.0","Brain RNA - pons [nTPM]":"36.2","Brain RNA - spinal cord [nTPM]":"25.0","Brain RNA - thalamus [nTPM]":"29.2","Brain RNA - white matter [nTPM]":"29.5","Single Cell Type RNA - Adipocytes [nTPM]":"6.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.1","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"8.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"4.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"8.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"30.7","Single Cell Type RNA - dendritic cells [nTPM]":"6.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"36.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"30.5","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.7","Single Cell Type RNA - Endothelial cells [nTPM]":"12.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.6","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"32.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"27.9","Single Cell Type RNA - Fibroblasts [nTPM]":"18.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.9","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"7.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.2","Single Cell Type RNA - Hepatocytes [nTPM]":"23.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"65.2","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.6","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"33.3","Single Cell Type RNA - Langerhans cells [nTPM]":"9.9","Single Cell Type RNA - Late spermatids [nTPM]":"2.8","Single Cell Type RNA - Leydig cells [nTPM]":"9.9","Single Cell Type RNA - Macrophages [nTPM]":"26.8","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"22.8","Single Cell Type RNA - Muller glia cells [nTPM]":"11.7","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.5","Single Cell Type RNA - Paneth cells [nTPM]":"15.8","Single Cell Type RNA - Peritubular cells [nTPM]":"9.1","Single Cell Type RNA - Plasma cells [nTPM]":"19.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"28.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"20.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.6","Single Cell Type RNA - Spermatocytes [nTPM]":"22.5","Single Cell Type RNA - Spermatogonia [nTPM]":"12.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"59.4","Single Cell Type RNA - T-cells [nTPM]":"8.5","Single Cell Type RNA - Theca cells [nTPM]":"6.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.4","Single Cell Type RNA - Urothelial cells [nTPM]":"6.5"},{"Gene":"GBA2","Gene synonym":["AD035","DKFZp762K054","KIAA1605","SPG46"],"Ensembl":"ENSG00000070610","Gene description":"Glucosylceramidase beta 2","Uniprot":["Q9HCG7"],"Chromosome":"9","Position":"35736866-35749228","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Sphingolipid metabolism","Steroid metabolism","Sterol metabolism"],"Molecular function":["Glycosidase","Glycosyltransferase","Hydrolase","Transferase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"114.7","Rod photoreceptor cells":"102.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024026"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA024026":"AB_1849530"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.00e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.24e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.60e-4"},"Tissue RNA - adipose tissue [nTPM]":"39.3","Tissue RNA - adrenal gland [nTPM]":"45.7","Tissue RNA - amygdala [nTPM]":"48.5","Tissue RNA - appendix [nTPM]":"23.2","Tissue RNA - basal ganglia [nTPM]":"47.5","Tissue RNA - bone marrow [nTPM]":"16.3","Tissue RNA - breast [nTPM]":"39.9","Tissue RNA - cerebellum [nTPM]":"52.8","Tissue RNA - cerebral cortex [nTPM]":"53.7","Tissue RNA - cervix [nTPM]":"46.4","Tissue RNA - choroid plexus [nTPM]":"63.3","Tissue RNA - colon [nTPM]":"83.5","Tissue RNA - duodenum [nTPM]":"54.2","Tissue RNA - endometrium 1 [nTPM]":"44.6","Tissue RNA - epididymis [nTPM]":"26.9","Tissue RNA - esophagus [nTPM]":"36.3","Tissue RNA - fallopian tube [nTPM]":"44.2","Tissue RNA - gallbladder [nTPM]":"26.3","Tissue RNA - heart muscle [nTPM]":"83.3","Tissue RNA - hippocampal formation [nTPM]":"47.2","Tissue RNA - hypothalamus [nTPM]":"54.2","Tissue RNA - kidney [nTPM]":"84.4","Tissue RNA - liver [nTPM]":"65.9","Tissue RNA - lung [nTPM]":"54.1","Tissue RNA - lymph node [nTPM]":"24.6","Tissue RNA - medulla oblongata [nTPM]":"54.1","Tissue RNA - midbrain [nTPM]":"56.2","Tissue RNA - ovary [nTPM]":"39.8","Tissue RNA - pancreas [nTPM]":"54.1","Tissue RNA - parathyroid gland [nTPM]":"37.2","Tissue RNA - pituitary gland [nTPM]":"65.5","Tissue RNA - placenta [nTPM]":"24.7","Tissue RNA - pons [nTPM]":"56.1","Tissue RNA - prostate [nTPM]":"60.2","Tissue RNA - rectum [nTPM]":"41.0","Tissue RNA - retina [nTPM]":"71.1","Tissue RNA - salivary gland [nTPM]":"50.0","Tissue RNA - seminal vesicle [nTPM]":"27.7","Tissue RNA - skeletal muscle [nTPM]":"75.8","Tissue RNA - skin 1 [nTPM]":"39.3","Tissue RNA - small intestine [nTPM]":"89.7","Tissue RNA - smooth muscle [nTPM]":"22.9","Tissue RNA - spinal cord [nTPM]":"45.1","Tissue RNA - spleen [nTPM]":"58.5","Tissue RNA - stomach 1 [nTPM]":"63.9","Tissue RNA - testis [nTPM]":"30.8","Tissue RNA - thalamus [nTPM]":"58.9","Tissue RNA - thymus [nTPM]":"18.3","Tissue RNA - thyroid gland [nTPM]":"61.7","Tissue RNA - tongue [nTPM]":"43.7","Tissue RNA - tonsil [nTPM]":"21.6","Tissue RNA - urinary bladder [nTPM]":"53.0","Tissue RNA - vagina [nTPM]":"40.9","Tissue RNA - white matter [nTPM]":"48.7","Cell RNA - A-431 [nTPM]":"18.1","Cell RNA - A549 [nTPM]":"29.3","Cell RNA - AF22 [nTPM]":"39.6","Cell RNA - AN3-CA [nTPM]":"38.4","Cell RNA - ASC diff [nTPM]":"18.8","Cell RNA - ASC TERT1 [nTPM]":"11.4","Cell RNA - BEWO [nTPM]":"40.0","Cell RNA - BJ [nTPM]":"24.1","Cell RNA - BJ hTERT+ [nTPM]":"18.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"25.0","Cell RNA - CACO-2 [nTPM]":"32.8","Cell RNA - CAPAN-2 [nTPM]":"14.1","Cell RNA - Daudi [nTPM]":"19.3","Cell RNA - EFO-21 [nTPM]":"17.1","Cell RNA - fHDF\/TERT166 [nTPM]":"14.7","Cell RNA - GAMG [nTPM]":"51.5","Cell RNA - HaCaT [nTPM]":"18.4","Cell RNA - HAP1 [nTPM]":"38.2","Cell RNA - HBEC3-KT [nTPM]":"16.2","Cell RNA - HBF TERT88 [nTPM]":"12.0","Cell RNA - HDLM-2 [nTPM]":"27.5","Cell RNA - HEK 293 [nTPM]":"26.2","Cell RNA - HEL [nTPM]":"20.8","Cell RNA - HeLa [nTPM]":"87.8","Cell RNA - Hep G2 [nTPM]":"35.6","Cell RNA - HHSteC [nTPM]":"20.8","Cell RNA - HL-60 [nTPM]":"31.2","Cell RNA - HMC-1 [nTPM]":"49.4","Cell RNA - HSkMC [nTPM]":"19.8","Cell RNA - hTCEpi [nTPM]":"29.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.3","Cell RNA - hTERT-HME1 [nTPM]":"21.1","Cell RNA - hTERT-RPE1 [nTPM]":"57.9","Cell RNA - HUVEC TERT2 [nTPM]":"63.4","Cell RNA - JURKAT [nTPM]":"18.9","Cell RNA - K-562 [nTPM]":"20.7","Cell RNA - Karpas-707 [nTPM]":"36.0","Cell RNA - LHCN-M2 [nTPM]":"22.6","Cell RNA - MCF7 [nTPM]":"18.0","Cell RNA - MOLT-4 [nTPM]":"8.5","Cell RNA - NB-4 [nTPM]":"32.0","Cell RNA - NTERA-2 [nTPM]":"41.2","Cell RNA - OE19 [nTPM]":"36.6","Cell RNA - PC-3 [nTPM]":"45.7","Cell RNA - REH [nTPM]":"15.5","Cell RNA - RH-30 [nTPM]":"16.0","Cell RNA - RPMI-8226 [nTPM]":"16.3","Cell RNA - RPTEC TERT1 [nTPM]":"33.3","Cell RNA - RT4 [nTPM]":"41.9","Cell RNA - SCLC-21H [nTPM]":"32.2","Cell RNA - SH-SY5Y [nTPM]":"43.0","Cell RNA - SiHa [nTPM]":"13.5","Cell RNA - SK-BR-3 [nTPM]":"33.3","Cell RNA - SK-MEL-30 [nTPM]":"24.5","Cell RNA - SuSa [nTPM]":"48.1","Cell RNA - T-47d [nTPM]":"22.8","Cell RNA - THP-1 [nTPM]":"27.8","Cell RNA - TIME [nTPM]":"44.6","Cell RNA - U-138 MG [nTPM]":"25.8","Cell RNA - U-2 OS [nTPM]":"30.9","Cell RNA - U-2197 [nTPM]":"22.4","Cell RNA - U-251 MG [nTPM]":"29.9","Cell RNA - U-266\/70 [nTPM]":"24.2","Cell RNA - U-266\/84 [nTPM]":"16.5","Cell RNA - U-698 [nTPM]":"16.0","Cell RNA - U-87 MG [nTPM]":"32.3","Cell RNA - U-937 [nTPM]":"11.3","Cell RNA - WM-115 [nTPM]":"20.5","Blood RNA - basophil [nTPM]":"11.1","Blood RNA - classical monocyte [nTPM]":"2.9","Blood RNA - eosinophil [nTPM]":"2.0","Blood RNA - gdT-cell [nTPM]":"3.8","Blood RNA - intermediate monocyte [nTPM]":"3.9","Blood RNA - MAIT T-cell [nTPM]":"2.5","Blood RNA - memory B-cell [nTPM]":"3.7","Blood RNA - memory CD4 T-cell [nTPM]":"3.7","Blood RNA - memory CD8 T-cell [nTPM]":"4.7","Blood RNA - myeloid DC [nTPM]":"2.8","Blood RNA - naive B-cell [nTPM]":"4.7","Blood RNA - naive CD4 T-cell [nTPM]":"2.2","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"3.2","Blood RNA - NK-cell [nTPM]":"2.4","Blood RNA - non-classical monocyte [nTPM]":"2.5","Blood RNA - plasmacytoid DC [nTPM]":"4.4","Blood RNA - T-reg [nTPM]":"2.8","Blood RNA - total PBMC [nTPM]":"2.2","Brain RNA - amygdala [nTPM]":"48.5","Brain RNA - basal ganglia [nTPM]":"47.5","Brain RNA - cerebellum [nTPM]":"52.8","Brain RNA - cerebral cortex [nTPM]":"53.7","Brain RNA - hippocampal formation [nTPM]":"47.2","Brain RNA - hypothalamus [nTPM]":"54.2","Brain RNA - medulla oblongata [nTPM]":"54.1","Brain RNA - midbrain [nTPM]":"56.2","Brain RNA - pons [nTPM]":"56.1","Brain RNA - spinal cord [nTPM]":"45.1","Brain RNA - thalamus [nTPM]":"58.9","Brain RNA - white matter [nTPM]":"48.7","Single Cell Type RNA - Adipocytes [nTPM]":"12.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.0","Single Cell Type RNA - Astrocytes [nTPM]":"45.1","Single Cell Type RNA - B-cells [nTPM]":"11.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"77.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"14.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"114.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.1","Single Cell Type RNA - dendritic cells [nTPM]":"16.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"71.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"10.5","Single Cell Type RNA - Early spermatids [nTPM]":"14.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.1","Single Cell Type RNA - Endothelial cells [nTPM]":"16.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"35.8","Single Cell Type RNA - Erythroid cells [nTPM]":"17.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.2","Single Cell Type RNA - Fibroblasts [nTPM]":"8.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"46.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.8","Single Cell Type RNA - granulocytes [nTPM]":"14.0","Single Cell Type RNA - Granulosa cells [nTPM]":"18.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"30.7","Single Cell Type RNA - Hepatocytes [nTPM]":"20.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.2","Single Cell Type RNA - Horizontal cells [nTPM]":"52.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"26.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"35.8","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"12.8","Single Cell Type RNA - Langerhans cells [nTPM]":"10.7","Single Cell Type RNA - Late spermatids [nTPM]":"24.3","Single Cell Type RNA - Leydig cells [nTPM]":"12.5","Single Cell Type RNA - Macrophages [nTPM]":"10.7","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"13.3","Single Cell Type RNA - Muller glia cells [nTPM]":"16.2","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.1","Single Cell Type RNA - Paneth cells [nTPM]":"57.6","Single Cell Type RNA - Peritubular cells [nTPM]":"9.8","Single Cell Type RNA - Plasma cells [nTPM]":"11.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"87.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"102.9","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.2","Single Cell Type RNA - Spermatocytes [nTPM]":"9.2","Single Cell Type RNA - Spermatogonia [nTPM]":"5.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.2","Single Cell Type RNA - T-cells [nTPM]":"9.4","Single Cell Type RNA - Theca cells [nTPM]":"11.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"41.4","Single Cell Type RNA - Urothelial cells [nTPM]":"26.3"},{"Gene":"GBE1","Gene synonym":[],"Ensembl":"ENSG00000114480","Gene description":"1,4-alpha-glucan branching enzyme 1","Uniprot":["Q04446"],"Chromosome":"3","Position":"81489703-81761645","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Glycogen biosynthesis"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant","Glycogen storage disease","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"149.1"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"287.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038073","HPA038074","HPA038075"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6500000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA038073":"AB_10673040","HPA038074":"AB_10672403","HPA038075":"AB_10674545"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-3"},"Tissue RNA - adipose tissue [nTPM]":"73.9","Tissue RNA - adrenal gland [nTPM]":"53.8","Tissue RNA - amygdala [nTPM]":"4.5","Tissue RNA - appendix [nTPM]":"14.9","Tissue RNA - basal ganglia [nTPM]":"5.7","Tissue RNA - bone marrow [nTPM]":"19.7","Tissue RNA - breast [nTPM]":"38.6","Tissue RNA - cerebellum [nTPM]":"7.1","Tissue RNA - cerebral cortex [nTPM]":"8.2","Tissue RNA - cervix [nTPM]":"14.2","Tissue RNA - choroid plexus [nTPM]":"14.2","Tissue RNA - colon [nTPM]":"11.8","Tissue RNA - duodenum [nTPM]":"13.2","Tissue RNA - endometrium 1 [nTPM]":"17.3","Tissue RNA - epididymis [nTPM]":"14.2","Tissue RNA - esophagus [nTPM]":"18.1","Tissue RNA - fallopian tube [nTPM]":"13.8","Tissue RNA - gallbladder [nTPM]":"13.0","Tissue RNA - heart muscle [nTPM]":"55.6","Tissue RNA - hippocampal formation [nTPM]":"6.2","Tissue RNA - hypothalamus [nTPM]":"8.2","Tissue RNA - kidney [nTPM]":"41.4","Tissue RNA - liver [nTPM]":"108.6","Tissue RNA - lung [nTPM]":"17.2","Tissue RNA - lymph node [nTPM]":"8.6","Tissue RNA - medulla oblongata [nTPM]":"10.7","Tissue RNA - midbrain [nTPM]":"18.7","Tissue RNA - ovary [nTPM]":"14.2","Tissue RNA - pancreas [nTPM]":"14.2","Tissue RNA - parathyroid gland [nTPM]":"19.1","Tissue RNA - pituitary gland [nTPM]":"10.4","Tissue RNA - placenta [nTPM]":"25.6","Tissue RNA - pons [nTPM]":"10.3","Tissue RNA - prostate [nTPM]":"13.2","Tissue RNA - rectum [nTPM]":"13.8","Tissue RNA - retina [nTPM]":"22.0","Tissue RNA - salivary gland [nTPM]":"15.5","Tissue RNA - seminal vesicle [nTPM]":"14.9","Tissue RNA - skeletal muscle [nTPM]":"149.1","Tissue RNA - skin 1 [nTPM]":"14.4","Tissue RNA - small intestine [nTPM]":"11.5","Tissue RNA - smooth muscle [nTPM]":"21.8","Tissue RNA - spinal cord [nTPM]":"7.0","Tissue RNA - spleen [nTPM]":"12.0","Tissue RNA - stomach 1 [nTPM]":"11.1","Tissue RNA - testis [nTPM]":"7.9","Tissue RNA - thalamus [nTPM]":"7.4","Tissue RNA - thymus [nTPM]":"11.4","Tissue RNA - thyroid gland [nTPM]":"19.6","Tissue RNA - tongue [nTPM]":"56.6","Tissue RNA - tonsil [nTPM]":"13.2","Tissue RNA - urinary bladder [nTPM]":"19.2","Tissue RNA - vagina [nTPM]":"13.9","Tissue RNA - white matter [nTPM]":"7.4","Cell RNA - A-431 [nTPM]":"61.3","Cell RNA - A549 [nTPM]":"36.2","Cell RNA - AF22 [nTPM]":"11.9","Cell RNA - AN3-CA [nTPM]":"168.7","Cell RNA - ASC diff [nTPM]":"287.6","Cell RNA - ASC TERT1 [nTPM]":"216.8","Cell RNA - BEWO [nTPM]":"21.5","Cell RNA - BJ [nTPM]":"99.1","Cell RNA - BJ hTERT+ [nTPM]":"140.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"58.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"97.6","Cell RNA - CACO-2 [nTPM]":"7.1","Cell RNA - CAPAN-2 [nTPM]":"15.6","Cell RNA - Daudi [nTPM]":"67.9","Cell RNA - EFO-21 [nTPM]":"42.7","Cell RNA - fHDF\/TERT166 [nTPM]":"122.5","Cell RNA - GAMG [nTPM]":"34.5","Cell RNA - HaCaT [nTPM]":"7.1","Cell RNA - HAP1 [nTPM]":"9.9","Cell RNA - HBEC3-KT [nTPM]":"45.7","Cell RNA - HBF TERT88 [nTPM]":"135.4","Cell RNA - HDLM-2 [nTPM]":"32.3","Cell RNA - HEK 293 [nTPM]":"6.4","Cell RNA - HEL [nTPM]":"21.2","Cell RNA - HeLa [nTPM]":"70.0","Cell RNA - Hep G2 [nTPM]":"22.8","Cell RNA - HHSteC [nTPM]":"197.5","Cell RNA - HL-60 [nTPM]":"72.2","Cell RNA - HMC-1 [nTPM]":"17.8","Cell RNA - HSkMC [nTPM]":"161.2","Cell RNA - hTCEpi [nTPM]":"33.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"93.5","Cell RNA - hTERT-HME1 [nTPM]":"95.5","Cell RNA - hTERT-RPE1 [nTPM]":"144.9","Cell RNA - HUVEC TERT2 [nTPM]":"130.5","Cell RNA - JURKAT [nTPM]":"8.0","Cell RNA - K-562 [nTPM]":"17.0","Cell RNA - Karpas-707 [nTPM]":"38.0","Cell RNA - LHCN-M2 [nTPM]":"191.1","Cell RNA - MCF7 [nTPM]":"17.8","Cell RNA - MOLT-4 [nTPM]":"12.5","Cell RNA - NB-4 [nTPM]":"92.7","Cell RNA - NTERA-2 [nTPM]":"12.0","Cell RNA - OE19 [nTPM]":"16.8","Cell RNA - PC-3 [nTPM]":"58.0","Cell RNA - REH [nTPM]":"22.9","Cell RNA - RH-30 [nTPM]":"53.6","Cell RNA - RPMI-8226 [nTPM]":"81.1","Cell RNA - RPTEC TERT1 [nTPM]":"41.4","Cell RNA - RT4 [nTPM]":"20.5","Cell RNA - SCLC-21H [nTPM]":"6.0","Cell RNA - SH-SY5Y [nTPM]":"7.9","Cell RNA - SiHa [nTPM]":"64.6","Cell RNA - SK-BR-3 [nTPM]":"18.7","Cell RNA - SK-MEL-30 [nTPM]":"20.9","Cell RNA - SuSa [nTPM]":"17.2","Cell RNA - T-47d [nTPM]":"13.3","Cell RNA - THP-1 [nTPM]":"58.9","Cell RNA - TIME [nTPM]":"183.4","Cell RNA - U-138 MG [nTPM]":"118.9","Cell RNA - U-2 OS [nTPM]":"28.1","Cell RNA - U-2197 [nTPM]":"84.7","Cell RNA - U-251 MG [nTPM]":"92.8","Cell RNA - U-266\/70 [nTPM]":"174.8","Cell RNA - U-266\/84 [nTPM]":"21.4","Cell RNA - U-698 [nTPM]":"24.6","Cell RNA - U-87 MG [nTPM]":"194.1","Cell RNA - U-937 [nTPM]":"47.8","Cell RNA - WM-115 [nTPM]":"49.8","Blood RNA - basophil [nTPM]":"7.5","Blood RNA - classical monocyte [nTPM]":"11.8","Blood RNA - eosinophil [nTPM]":"15.6","Blood RNA - gdT-cell [nTPM]":"5.2","Blood RNA - intermediate monocyte [nTPM]":"10.8","Blood RNA - MAIT T-cell [nTPM]":"5.1","Blood RNA - memory B-cell [nTPM]":"11.6","Blood RNA - memory CD4 T-cell [nTPM]":"5.6","Blood RNA - memory CD8 T-cell [nTPM]":"5.7","Blood RNA - myeloid DC [nTPM]":"13.8","Blood RNA - naive B-cell [nTPM]":"12.5","Blood RNA - naive CD4 T-cell [nTPM]":"6.4","Blood RNA - naive CD8 T-cell [nTPM]":"6.6","Blood RNA - neutrophil [nTPM]":"11.4","Blood RNA - NK-cell [nTPM]":"13.5","Blood RNA - non-classical monocyte [nTPM]":"11.8","Blood RNA - plasmacytoid DC [nTPM]":"4.8","Blood RNA - T-reg [nTPM]":"5.1","Blood RNA - total PBMC [nTPM]":"6.5","Brain RNA - amygdala [nTPM]":"4.5","Brain RNA - basal ganglia [nTPM]":"5.7","Brain RNA - cerebellum [nTPM]":"7.1","Brain RNA - cerebral cortex [nTPM]":"8.2","Brain RNA - hippocampal formation [nTPM]":"6.2","Brain RNA - hypothalamus [nTPM]":"8.2","Brain RNA - medulla oblongata [nTPM]":"10.7","Brain RNA - midbrain [nTPM]":"18.7","Brain RNA - pons [nTPM]":"10.3","Brain RNA - spinal cord [nTPM]":"7.0","Brain RNA - thalamus [nTPM]":"7.4","Brain RNA - white matter [nTPM]":"7.4","Single Cell Type RNA - Adipocytes [nTPM]":"49.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.4","Single Cell Type RNA - Astrocytes [nTPM]":"31.3","Single Cell Type RNA - B-cells [nTPM]":"14.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"36.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"27.3","Single Cell Type RNA - Bipolar cells [nTPM]":"18.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"60.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"21.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"30.3","Single Cell Type RNA - dendritic cells [nTPM]":"8.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"41.1","Single Cell Type RNA - Ductal cells [nTPM]":"32.1","Single Cell Type RNA - Early spermatids [nTPM]":"36.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.2","Single Cell Type RNA - Endothelial cells [nTPM]":"32.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.1","Single Cell Type RNA - Erythroid cells [nTPM]":"4.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"52.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"74.0","Single Cell Type RNA - Fibroblasts [nTPM]":"34.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.7","Single Cell Type RNA - granulocytes [nTPM]":"43.1","Single Cell Type RNA - Granulosa cells [nTPM]":"16.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.4","Single Cell Type RNA - Hepatocytes [nTPM]":"75.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"26.3","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"47.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.7","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"12.9","Single Cell Type RNA - Langerhans cells [nTPM]":"21.3","Single Cell Type RNA - Late spermatids [nTPM]":"16.9","Single Cell Type RNA - Leydig cells [nTPM]":"17.4","Single Cell Type RNA - Macrophages [nTPM]":"17.3","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"87.1","Single Cell Type RNA - monocytes [nTPM]":"16.3","Single Cell Type RNA - Muller glia cells [nTPM]":"10.4","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"49.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"63.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"37.8","Single Cell Type RNA - Paneth cells [nTPM]":"5.8","Single Cell Type RNA - Peritubular cells [nTPM]":"13.2","Single Cell Type RNA - Plasma cells [nTPM]":"12.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"50.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"25.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.8","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"45.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.7","Single Cell Type RNA - Spermatocytes [nTPM]":"6.9","Single Cell Type RNA - Spermatogonia [nTPM]":"7.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"54.9","Single Cell Type RNA - T-cells [nTPM]":"8.7","Single Cell Type RNA - Theca cells [nTPM]":"34.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.3","Single Cell Type RNA - Urothelial cells [nTPM]":"14.5"},{"Gene":"GCDH","Gene synonym":["ACAD5"],"Ensembl":"ENSG00000105607","Gene description":"Glutaryl-CoA dehydrogenase","Uniprot":["Q92947"],"Chromosome":"19","Position":"12891160-12914207","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Glutaricaciduria"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"89.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"115.5","Proximal tubular cells":"147.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043252","HPA048492"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA043252":"AB_2678390","HPA048492":"AB_2680418"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.20e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.28e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.35e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.50e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.79e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Tissue RNA - adipose tissue [nTPM]":"16.8","Tissue RNA - adrenal gland [nTPM]":"17.8","Tissue RNA - amygdala [nTPM]":"20.2","Tissue RNA - appendix [nTPM]":"11.2","Tissue RNA - basal ganglia [nTPM]":"22.4","Tissue RNA - bone marrow [nTPM]":"13.0","Tissue RNA - breast [nTPM]":"15.6","Tissue RNA - cerebellum [nTPM]":"22.1","Tissue RNA - cerebral cortex [nTPM]":"23.3","Tissue RNA - cervix [nTPM]":"10.2","Tissue RNA - choroid plexus [nTPM]":"21.8","Tissue RNA - colon [nTPM]":"13.2","Tissue RNA - duodenum [nTPM]":"11.8","Tissue RNA - endometrium 1 [nTPM]":"12.6","Tissue RNA - epididymis [nTPM]":"8.6","Tissue RNA - esophagus [nTPM]":"14.0","Tissue RNA - fallopian tube [nTPM]":"15.2","Tissue RNA - gallbladder [nTPM]":"8.4","Tissue RNA - heart muscle [nTPM]":"29.3","Tissue RNA - hippocampal formation [nTPM]":"19.2","Tissue RNA - hypothalamus [nTPM]":"19.4","Tissue RNA - kidney [nTPM]":"24.5","Tissue RNA - liver [nTPM]":"89.1","Tissue RNA - lung [nTPM]":"9.3","Tissue RNA - lymph node [nTPM]":"16.8","Tissue RNA - medulla oblongata [nTPM]":"20.7","Tissue RNA - midbrain [nTPM]":"20.9","Tissue RNA - ovary [nTPM]":"16.8","Tissue RNA - pancreas [nTPM]":"15.5","Tissue RNA - parathyroid gland [nTPM]":"11.5","Tissue RNA - pituitary gland [nTPM]":"10.6","Tissue RNA - placenta [nTPM]":"5.4","Tissue RNA - pons [nTPM]":"21.0","Tissue RNA - prostate [nTPM]":"13.6","Tissue RNA - rectum [nTPM]":"8.5","Tissue RNA - retina [nTPM]":"5.5","Tissue RNA - salivary gland [nTPM]":"20.0","Tissue RNA - seminal vesicle [nTPM]":"11.5","Tissue RNA - skeletal muscle [nTPM]":"30.5","Tissue RNA - skin 1 [nTPM]":"10.1","Tissue RNA - small intestine [nTPM]":"13.0","Tissue RNA - smooth muscle [nTPM]":"8.2","Tissue RNA - spinal cord [nTPM]":"19.9","Tissue RNA - spleen [nTPM]":"12.8","Tissue RNA - stomach 1 [nTPM]":"18.6","Tissue RNA - testis [nTPM]":"4.5","Tissue RNA - thalamus [nTPM]":"20.9","Tissue RNA - thymus [nTPM]":"17.8","Tissue RNA - thyroid gland [nTPM]":"11.9","Tissue RNA - tongue [nTPM]":"27.1","Tissue RNA - tonsil [nTPM]":"11.9","Tissue RNA - urinary bladder [nTPM]":"14.9","Tissue RNA - vagina [nTPM]":"9.9","Tissue RNA - white matter [nTPM]":"22.7","Cell RNA - A-431 [nTPM]":"22.9","Cell RNA - A549 [nTPM]":"14.1","Cell RNA - AF22 [nTPM]":"15.0","Cell RNA - AN3-CA [nTPM]":"27.5","Cell RNA - ASC diff [nTPM]":"21.4","Cell RNA - ASC TERT1 [nTPM]":"9.8","Cell RNA - BEWO [nTPM]":"13.8","Cell RNA - BJ [nTPM]":"17.2","Cell RNA - BJ hTERT+ [nTPM]":"11.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.7","Cell RNA - CACO-2 [nTPM]":"26.9","Cell RNA - CAPAN-2 [nTPM]":"10.8","Cell RNA - Daudi [nTPM]":"33.0","Cell RNA - EFO-21 [nTPM]":"31.9","Cell RNA - fHDF\/TERT166 [nTPM]":"10.5","Cell RNA - GAMG [nTPM]":"10.8","Cell RNA - HaCaT [nTPM]":"15.6","Cell RNA - HAP1 [nTPM]":"20.8","Cell RNA - HBEC3-KT [nTPM]":"16.4","Cell RNA - HBF TERT88 [nTPM]":"10.6","Cell RNA - HDLM-2 [nTPM]":"28.6","Cell RNA - HEK 293 [nTPM]":"22.8","Cell RNA - HEL [nTPM]":"21.0","Cell RNA - HeLa [nTPM]":"24.6","Cell RNA - Hep G2 [nTPM]":"33.1","Cell RNA - HHSteC [nTPM]":"24.8","Cell RNA - HL-60 [nTPM]":"43.7","Cell RNA - HMC-1 [nTPM]":"18.8","Cell RNA - HSkMC [nTPM]":"13.8","Cell RNA - hTCEpi [nTPM]":"19.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.3","Cell RNA - hTERT-HME1 [nTPM]":"16.1","Cell RNA - hTERT-RPE1 [nTPM]":"8.8","Cell RNA - HUVEC TERT2 [nTPM]":"18.1","Cell RNA - JURKAT [nTPM]":"44.4","Cell RNA - K-562 [nTPM]":"51.8","Cell RNA - Karpas-707 [nTPM]":"11.4","Cell RNA - LHCN-M2 [nTPM]":"10.7","Cell RNA - MCF7 [nTPM]":"28.9","Cell RNA - MOLT-4 [nTPM]":"51.7","Cell RNA - NB-4 [nTPM]":"41.7","Cell RNA - NTERA-2 [nTPM]":"16.7","Cell RNA - OE19 [nTPM]":"22.0","Cell RNA - PC-3 [nTPM]":"36.1","Cell RNA - REH [nTPM]":"48.2","Cell RNA - RH-30 [nTPM]":"15.3","Cell RNA - RPMI-8226 [nTPM]":"68.9","Cell RNA - RPTEC TERT1 [nTPM]":"12.6","Cell RNA - RT4 [nTPM]":"12.1","Cell RNA - SCLC-21H [nTPM]":"32.3","Cell RNA - SH-SY5Y [nTPM]":"18.9","Cell RNA - SiHa [nTPM]":"22.8","Cell RNA - SK-BR-3 [nTPM]":"22.6","Cell RNA - SK-MEL-30 [nTPM]":"16.7","Cell RNA - SuSa [nTPM]":"9.6","Cell RNA - T-47d [nTPM]":"17.8","Cell RNA - THP-1 [nTPM]":"29.3","Cell RNA - TIME [nTPM]":"13.3","Cell RNA - U-138 MG [nTPM]":"18.0","Cell RNA - U-2 OS [nTPM]":"12.9","Cell RNA - U-2197 [nTPM]":"29.9","Cell RNA - U-251 MG [nTPM]":"18.2","Cell RNA - U-266\/70 [nTPM]":"59.5","Cell RNA - U-266\/84 [nTPM]":"32.2","Cell RNA - U-698 [nTPM]":"34.6","Cell RNA - U-87 MG [nTPM]":"11.0","Cell RNA - U-937 [nTPM]":"50.7","Cell RNA - WM-115 [nTPM]":"15.4","Blood RNA - basophil [nTPM]":"13.9","Blood RNA - classical monocyte [nTPM]":"13.9","Blood RNA - eosinophil [nTPM]":"8.5","Blood RNA - gdT-cell [nTPM]":"18.8","Blood RNA - intermediate monocyte [nTPM]":"12.1","Blood RNA - MAIT T-cell [nTPM]":"18.8","Blood RNA - memory B-cell [nTPM]":"18.1","Blood RNA - memory CD4 T-cell [nTPM]":"23.2","Blood RNA - memory CD8 T-cell [nTPM]":"21.0","Blood RNA - myeloid DC [nTPM]":"24.0","Blood RNA - naive B-cell [nTPM]":"19.5","Blood RNA - naive CD4 T-cell [nTPM]":"30.9","Blood RNA - naive CD8 T-cell [nTPM]":"23.8","Blood RNA - neutrophil [nTPM]":"3.1","Blood RNA - NK-cell [nTPM]":"38.8","Blood RNA - non-classical monocyte [nTPM]":"9.8","Blood RNA - plasmacytoid DC [nTPM]":"14.7","Blood RNA - T-reg [nTPM]":"21.4","Blood RNA - total PBMC [nTPM]":"20.0","Brain RNA - amygdala [nTPM]":"20.2","Brain RNA - basal ganglia [nTPM]":"22.4","Brain RNA - cerebellum [nTPM]":"22.1","Brain RNA - cerebral cortex [nTPM]":"23.3","Brain RNA - hippocampal formation [nTPM]":"19.2","Brain RNA - hypothalamus [nTPM]":"19.4","Brain RNA - medulla oblongata [nTPM]":"20.7","Brain RNA - midbrain [nTPM]":"20.9","Brain RNA - pons [nTPM]":"21.0","Brain RNA - spinal cord [nTPM]":"19.9","Brain RNA - thalamus [nTPM]":"20.9","Brain RNA - white matter [nTPM]":"22.7","Single Cell Type RNA - Adipocytes [nTPM]":"6.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.3","Single Cell Type RNA - Astrocytes [nTPM]":"25.5","Single Cell Type RNA - B-cells [nTPM]":"21.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"14.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"8.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.2","Single Cell Type RNA - dendritic cells [nTPM]":"17.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"52.8","Single Cell Type RNA - Ductal cells [nTPM]":"14.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.0","Single Cell Type RNA - Endothelial cells [nTPM]":"7.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.6","Single Cell Type RNA - Erythroid cells [nTPM]":"60.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.5","Single Cell Type RNA - Fibroblasts [nTPM]":"10.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.9","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"19.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"115.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"21.5","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.8","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"14.4","Single Cell Type RNA - Langerhans cells [nTPM]":"5.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.8","Single Cell Type RNA - Leydig cells [nTPM]":"13.1","Single Cell Type RNA - Macrophages [nTPM]":"9.9","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"20.7","Single Cell Type RNA - Muller glia cells [nTPM]":"18.6","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.2","Single Cell Type RNA - Paneth cells [nTPM]":"9.7","Single Cell Type RNA - Peritubular cells [nTPM]":"12.8","Single Cell Type RNA - Plasma cells [nTPM]":"25.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"147.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.8","Single Cell Type RNA - Spermatocytes [nTPM]":"8.3","Single Cell Type RNA - Spermatogonia [nTPM]":"7.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.3","Single Cell Type RNA - T-cells [nTPM]":"20.9","Single Cell Type RNA - Theca cells [nTPM]":"33.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.6","Single Cell Type RNA - Urothelial cells [nTPM]":"12.1"},{"Gene":"GCH1","Gene synonym":["DYT14","DYT5","DYT5a","GCH","GTPCH1"],"Ensembl":"ENSG00000131979","Gene description":"GTP cyclohydrolase 1","Uniprot":["P30793"],"Chromosome":"14","Position":"54842008-54902826","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Tetrahydrobiopterin biosynthesis"],"Molecular function":["Allosteric enzyme","Hydrolase"],"Disease involvement":["Disease variant","Dystonia","Parkinsonism","Phenylketonuria"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"31.4","liver":"36.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Enteroendocrine cells":"212.5","Hepatocytes":"94.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"11.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"23.5","Daudi":"25.0","JURKAT":"23.0","SH-SY5Y":"50.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"midbrain":"12.7"},"Antibody":["HPA028612"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear membrane","Cytosol"],"Antibody RRID":{"HPA028612":"AB_10602135"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.69e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.41e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.67e-4"},"Tissue RNA - adipose tissue [nTPM]":"2.4","Tissue RNA - adrenal gland [nTPM]":"6.0","Tissue RNA - amygdala [nTPM]":"2.1","Tissue RNA - appendix [nTPM]":"8.1","Tissue RNA - basal ganglia [nTPM]":"3.0","Tissue RNA - bone marrow [nTPM]":"31.4","Tissue RNA - breast [nTPM]":"1.8","Tissue RNA - cerebellum [nTPM]":"1.1","Tissue RNA - cerebral cortex [nTPM]":"2.0","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"1.5","Tissue RNA - colon [nTPM]":"2.4","Tissue RNA - duodenum [nTPM]":"9.4","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"3.5","Tissue RNA - fallopian tube [nTPM]":"1.2","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"1.9","Tissue RNA - hippocampal formation [nTPM]":"1.9","Tissue RNA - hypothalamus [nTPM]":"4.8","Tissue RNA - kidney [nTPM]":"4.6","Tissue RNA - liver [nTPM]":"36.7","Tissue RNA - lung [nTPM]":"4.1","Tissue RNA - lymph node [nTPM]":"7.0","Tissue RNA - medulla oblongata [nTPM]":"3.5","Tissue RNA - midbrain [nTPM]":"16.1","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"2.6","Tissue RNA - parathyroid gland [nTPM]":"0.9","Tissue RNA - pituitary gland [nTPM]":"1.8","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"8.4","Tissue RNA - prostate [nTPM]":"1.5","Tissue RNA - rectum [nTPM]":"2.4","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"1.7","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"2.2","Tissue RNA - small intestine [nTPM]":"7.5","Tissue RNA - smooth muscle [nTPM]":"1.1","Tissue RNA - spinal cord [nTPM]":"2.4","Tissue RNA - spleen [nTPM]":"6.9","Tissue RNA - stomach 1 [nTPM]":"2.8","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"7.8","Tissue RNA - thymus [nTPM]":"3.8","Tissue RNA - thyroid gland [nTPM]":"0.8","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"2.0","Tissue RNA - urinary bladder [nTPM]":"3.3","Tissue RNA - vagina [nTPM]":"1.4","Tissue RNA - white matter [nTPM]":"2.0","Cell RNA - A-431 [nTPM]":"4.7","Cell RNA - A549 [nTPM]":"0.6","Cell RNA - AF22 [nTPM]":"1.3","Cell RNA - AN3-CA [nTPM]":"7.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"23.5","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"2.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.9","Cell RNA - CACO-2 [nTPM]":"1.4","Cell RNA - CAPAN-2 [nTPM]":"1.0","Cell RNA - Daudi [nTPM]":"25.0","Cell RNA - EFO-21 [nTPM]":"6.9","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"5.8","Cell RNA - HaCaT [nTPM]":"4.0","Cell RNA - HAP1 [nTPM]":"4.9","Cell RNA - HBEC3-KT [nTPM]":"1.5","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"10.9","Cell RNA - HEK 293 [nTPM]":"5.2","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"3.1","Cell RNA - HHSteC [nTPM]":"8.4","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.9","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.2","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.7","Cell RNA - JURKAT [nTPM]":"23.0","Cell RNA - K-562 [nTPM]":"2.8","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"5.0","Cell RNA - MOLT-4 [nTPM]":"15.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"6.5","Cell RNA - PC-3 [nTPM]":"8.2","Cell RNA - REH [nTPM]":"9.6","Cell RNA - RH-30 [nTPM]":"2.8","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"2.9","Cell RNA - RT4 [nTPM]":"1.6","Cell RNA - SCLC-21H [nTPM]":"11.6","Cell RNA - SH-SY5Y [nTPM]":"50.9","Cell RNA - SiHa [nTPM]":"3.3","Cell RNA - SK-BR-3 [nTPM]":"2.4","Cell RNA - SK-MEL-30 [nTPM]":"1.6","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"2.9","Cell RNA - THP-1 [nTPM]":"1.5","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"4.0","Cell RNA - U-2197 [nTPM]":"9.9","Cell RNA - U-251 MG [nTPM]":"3.8","Cell RNA - U-266\/70 [nTPM]":"10.5","Cell RNA - U-266\/84 [nTPM]":"8.4","Cell RNA - U-698 [nTPM]":"7.8","Cell RNA - U-87 MG [nTPM]":"3.1","Cell RNA - U-937 [nTPM]":"8.4","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.6","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"2.8","Blood RNA - intermediate monocyte [nTPM]":"5.3","Blood RNA - MAIT T-cell [nTPM]":"2.1","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"1.0","Blood RNA - memory CD8 T-cell [nTPM]":"1.5","Blood RNA - myeloid DC [nTPM]":"2.8","Blood RNA - naive B-cell [nTPM]":"1.9","Blood RNA - naive CD4 T-cell [nTPM]":"2.5","Blood RNA - naive CD8 T-cell [nTPM]":"1.3","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"11.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"2.1","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"2.1","Brain RNA - basal ganglia [nTPM]":"3.0","Brain RNA - cerebellum [nTPM]":"1.1","Brain RNA - cerebral cortex [nTPM]":"2.0","Brain RNA - hippocampal formation [nTPM]":"1.9","Brain RNA - hypothalamus [nTPM]":"4.8","Brain RNA - medulla oblongata [nTPM]":"3.5","Brain RNA - midbrain [nTPM]":"16.1","Brain RNA - pons [nTPM]":"8.4","Brain RNA - spinal cord [nTPM]":"2.4","Brain RNA - thalamus [nTPM]":"7.8","Brain RNA - white matter [nTPM]":"2.0","Single Cell Type RNA - Adipocytes [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"33.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"74.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"30.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"23.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"13.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - dendritic cells [nTPM]":"50.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"21.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.8","Single Cell Type RNA - Endothelial cells [nTPM]":"19.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"212.5","Single Cell Type RNA - Erythroid cells [nTPM]":"10.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"44.3","Single Cell Type RNA - Fibroblasts [nTPM]":"15.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"43.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"29.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"94.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"22.7","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"28.0","Single Cell Type RNA - Langerhans cells [nTPM]":"33.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"55.8","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"29.5","Single Cell Type RNA - Muller glia cells [nTPM]":"0.7","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.0","Single Cell Type RNA - Paneth cells [nTPM]":"13.6","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"14.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"48.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.5","Single Cell Type RNA - Spermatocytes [nTPM]":"2.2","Single Cell Type RNA - Spermatogonia [nTPM]":"6.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"76.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.2","Single Cell Type RNA - T-cells [nTPM]":"41.8","Single Cell Type RNA - Theca cells [nTPM]":"11.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.2","Single Cell Type RNA - Urothelial cells [nTPM]":"39.0"},{"Gene":"GCK","Gene synonym":["HK4","MODY2"],"Ensembl":"ENSG00000106633","Gene description":"Glucokinase","Uniprot":["P35557"],"Chromosome":"7","Position":"44143213-44198170","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Glycolysis"],"Molecular function":["Allosteric enzyme","Kinase","Transferase"],"Disease involvement":["Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"12.6","choroid plexus":"7.4","heart muscle":"8.8","liver":"21.5","pituitary gland":"23.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"5.0","Cardiomyocytes":"4.9","Fibroblasts":"5.2","Horizontal cells":"5.0","Smooth muscle cells":"3.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"4.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"2.3","naive CD4 T-cell":"2.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"SCLC-21H":"6.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007034","HPA007093"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":["Golgi apparatus","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA007034":"AB_1079050","HPA007093":"AB_1079051"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.8","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"8.9","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"8.3","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"0.7","Tissue RNA - cerebellum [nTPM]":"8.1","Tissue RNA - cerebral cortex [nTPM]":"9.5","Tissue RNA - cervix [nTPM]":"2.8","Tissue RNA - choroid plexus [nTPM]":"7.4","Tissue RNA - colon [nTPM]":"0.5","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"1.2","Tissue RNA - epididymis [nTPM]":"0.8","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"1.2","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"8.8","Tissue RNA - hippocampal formation [nTPM]":"8.2","Tissue RNA - hypothalamus [nTPM]":"11.0","Tissue RNA - kidney [nTPM]":"1.2","Tissue RNA - liver [nTPM]":"21.5","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"9.0","Tissue RNA - midbrain [nTPM]":"9.9","Tissue RNA - ovary [nTPM]":"1.4","Tissue RNA - pancreas [nTPM]":"1.8","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"23.9","Tissue RNA - placenta [nTPM]":"1.6","Tissue RNA - pons [nTPM]":"9.1","Tissue RNA - prostate [nTPM]":"1.2","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"1.0","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.7","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"8.3","Tissue RNA - spleen [nTPM]":"0.6","Tissue RNA - stomach 1 [nTPM]":"0.6","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"12.6","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.5","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"1.1","Tissue RNA - vagina [nTPM]":"2.0","Tissue RNA - white matter [nTPM]":"7.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.7","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.5","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.7","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"6.6","Cell RNA - SH-SY5Y [nTPM]":"1.2","Cell RNA - SiHa [nTPM]":"1.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.6","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"2.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.7","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"2.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"8.9","Brain RNA - basal ganglia [nTPM]":"8.3","Brain RNA - cerebellum [nTPM]":"8.1","Brain RNA - cerebral cortex [nTPM]":"9.5","Brain RNA - hippocampal formation [nTPM]":"8.2","Brain RNA - hypothalamus [nTPM]":"11.0","Brain RNA - medulla oblongata [nTPM]":"9.0","Brain RNA - midbrain [nTPM]":"9.9","Brain RNA - pons [nTPM]":"9.1","Brain RNA - spinal cord [nTPM]":"8.3","Brain RNA - thalamus [nTPM]":"12.6","Brain RNA - white matter [nTPM]":"7.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"5.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"5.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.7","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"GCLC","Gene synonym":["GCS","GLCL","GLCLC"],"Ensembl":"ENSG00000001084","Gene description":"Glutamate-cysteine ligase catalytic subunit","Uniprot":["P48506"],"Chromosome":"6","Position":"53497341-53616970","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Glutathione biosynthesis"],"Molecular function":["Ligase"],"Disease involvement":["Disease variant","Hereditary hemolytic anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"152.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Enteroendocrine cells":"220.7","Urothelial cells":"144.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"4.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"205.4","Hep G2":"178.2","OE19":"287.5","RT4":"189.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009569","HPA036359","HPA036360"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5800000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli","Cytosol"],"Antibody RRID":{"CAB009569":"AB_675582","HPA036359":"AB_10672243","HPA036360":"AB_10669789"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.83e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.24e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Tissue RNA - adipose tissue [nTPM]":"26.7","Tissue RNA - adrenal gland [nTPM]":"18.3","Tissue RNA - amygdala [nTPM]":"18.5","Tissue RNA - appendix [nTPM]":"16.6","Tissue RNA - basal ganglia [nTPM]":"24.9","Tissue RNA - bone marrow [nTPM]":"37.8","Tissue RNA - breast [nTPM]":"27.2","Tissue RNA - cerebellum [nTPM]":"18.1","Tissue RNA - cerebral cortex [nTPM]":"23.3","Tissue RNA - cervix [nTPM]":"9.5","Tissue RNA - choroid plexus [nTPM]":"14.1","Tissue RNA - colon [nTPM]":"22.8","Tissue RNA - duodenum [nTPM]":"41.9","Tissue RNA - endometrium 1 [nTPM]":"19.2","Tissue RNA - epididymis [nTPM]":"10.8","Tissue RNA - esophagus [nTPM]":"37.0","Tissue RNA - fallopian tube [nTPM]":"62.9","Tissue RNA - gallbladder [nTPM]":"32.1","Tissue RNA - heart muscle [nTPM]":"16.4","Tissue RNA - hippocampal formation [nTPM]":"16.8","Tissue RNA - hypothalamus [nTPM]":"18.9","Tissue RNA - kidney [nTPM]":"34.1","Tissue RNA - liver [nTPM]":"152.1","Tissue RNA - lung [nTPM]":"10.9","Tissue RNA - lymph node [nTPM]":"26.2","Tissue RNA - medulla oblongata [nTPM]":"18.4","Tissue RNA - midbrain [nTPM]":"19.7","Tissue RNA - ovary [nTPM]":"8.5","Tissue RNA - pancreas [nTPM]":"15.9","Tissue RNA - parathyroid gland [nTPM]":"18.3","Tissue RNA - pituitary gland [nTPM]":"4.8","Tissue RNA - placenta [nTPM]":"9.1","Tissue RNA - pons [nTPM]":"20.4","Tissue RNA - prostate [nTPM]":"26.9","Tissue RNA - rectum [nTPM]":"26.0","Tissue RNA - retina [nTPM]":"14.4","Tissue RNA - salivary gland [nTPM]":"13.1","Tissue RNA - seminal vesicle [nTPM]":"15.8","Tissue RNA - skeletal muscle [nTPM]":"11.4","Tissue RNA - skin 1 [nTPM]":"18.8","Tissue RNA - small intestine [nTPM]":"32.2","Tissue RNA - smooth muscle [nTPM]":"16.0","Tissue RNA - spinal cord [nTPM]":"18.2","Tissue RNA - spleen [nTPM]":"39.1","Tissue RNA - stomach 1 [nTPM]":"32.9","Tissue RNA - testis [nTPM]":"11.3","Tissue RNA - thalamus [nTPM]":"22.5","Tissue RNA - thymus [nTPM]":"13.7","Tissue RNA - thyroid gland [nTPM]":"30.0","Tissue RNA - tongue [nTPM]":"14.5","Tissue RNA - tonsil [nTPM]":"24.0","Tissue RNA - urinary bladder [nTPM]":"63.7","Tissue RNA - vagina [nTPM]":"14.5","Tissue RNA - white matter [nTPM]":"36.0","Cell RNA - A-431 [nTPM]":"31.3","Cell RNA - A549 [nTPM]":"205.4","Cell RNA - AF22 [nTPM]":"16.5","Cell RNA - AN3-CA [nTPM]":"39.1","Cell RNA - ASC diff [nTPM]":"19.4","Cell RNA - ASC TERT1 [nTPM]":"8.6","Cell RNA - BEWO [nTPM]":"22.1","Cell RNA - BJ [nTPM]":"15.5","Cell RNA - BJ hTERT+ [nTPM]":"24.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.3","Cell RNA - CACO-2 [nTPM]":"30.5","Cell RNA - CAPAN-2 [nTPM]":"70.7","Cell RNA - Daudi [nTPM]":"59.1","Cell RNA - EFO-21 [nTPM]":"28.7","Cell RNA - fHDF\/TERT166 [nTPM]":"14.1","Cell RNA - GAMG [nTPM]":"86.9","Cell RNA - HaCaT [nTPM]":"43.3","Cell RNA - HAP1 [nTPM]":"50.7","Cell RNA - HBEC3-KT [nTPM]":"112.5","Cell RNA - HBF TERT88 [nTPM]":"15.3","Cell RNA - HDLM-2 [nTPM]":"46.9","Cell RNA - HEK 293 [nTPM]":"31.4","Cell RNA - HEL [nTPM]":"39.6","Cell RNA - HeLa [nTPM]":"38.3","Cell RNA - Hep G2 [nTPM]":"178.2","Cell RNA - HHSteC [nTPM]":"22.1","Cell RNA - HL-60 [nTPM]":"52.8","Cell RNA - HMC-1 [nTPM]":"23.5","Cell RNA - HSkMC [nTPM]":"13.5","Cell RNA - hTCEpi [nTPM]":"46.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.8","Cell RNA - hTERT-HME1 [nTPM]":"56.8","Cell RNA - hTERT-RPE1 [nTPM]":"15.0","Cell RNA - HUVEC TERT2 [nTPM]":"17.7","Cell RNA - JURKAT [nTPM]":"50.9","Cell RNA - K-562 [nTPM]":"22.4","Cell RNA - Karpas-707 [nTPM]":"18.2","Cell RNA - LHCN-M2 [nTPM]":"5.6","Cell RNA - MCF7 [nTPM]":"32.9","Cell RNA - MOLT-4 [nTPM]":"45.5","Cell RNA - NB-4 [nTPM]":"20.9","Cell RNA - NTERA-2 [nTPM]":"30.6","Cell RNA - OE19 [nTPM]":"287.5","Cell RNA - PC-3 [nTPM]":"19.2","Cell RNA - REH [nTPM]":"14.9","Cell RNA - RH-30 [nTPM]":"10.2","Cell RNA - RPMI-8226 [nTPM]":"52.1","Cell RNA - RPTEC TERT1 [nTPM]":"37.0","Cell RNA - RT4 [nTPM]":"189.8","Cell RNA - SCLC-21H [nTPM]":"47.5","Cell RNA - SH-SY5Y [nTPM]":"23.3","Cell RNA - SiHa [nTPM]":"25.9","Cell RNA - SK-BR-3 [nTPM]":"40.9","Cell RNA - SK-MEL-30 [nTPM]":"27.8","Cell RNA - SuSa [nTPM]":"23.8","Cell RNA - T-47d [nTPM]":"28.2","Cell RNA - THP-1 [nTPM]":"24.6","Cell RNA - TIME [nTPM]":"24.6","Cell RNA - U-138 MG [nTPM]":"10.2","Cell RNA - U-2 OS [nTPM]":"35.5","Cell RNA - U-2197 [nTPM]":"26.0","Cell RNA - U-251 MG [nTPM]":"23.4","Cell RNA - U-266\/70 [nTPM]":"24.1","Cell RNA - U-266\/84 [nTPM]":"39.9","Cell RNA - U-698 [nTPM]":"34.0","Cell RNA - U-87 MG [nTPM]":"25.6","Cell RNA - U-937 [nTPM]":"37.0","Cell RNA - WM-115 [nTPM]":"17.5","Blood RNA - basophil [nTPM]":"1.2","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"2.3","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"4.2","Blood RNA - non-classical monocyte [nTPM]":"1.0","Blood RNA - plasmacytoid DC [nTPM]":"1.6","Blood RNA - T-reg [nTPM]":"0.9","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"18.5","Brain RNA - basal ganglia [nTPM]":"24.9","Brain RNA - cerebellum [nTPM]":"18.1","Brain RNA - cerebral cortex [nTPM]":"23.3","Brain RNA - hippocampal formation [nTPM]":"16.8","Brain RNA - hypothalamus [nTPM]":"18.9","Brain RNA - medulla oblongata [nTPM]":"18.4","Brain RNA - midbrain [nTPM]":"19.7","Brain RNA - pons [nTPM]":"20.4","Brain RNA - spinal cord [nTPM]":"18.2","Brain RNA - thalamus [nTPM]":"22.5","Brain RNA - white matter [nTPM]":"36.0","Single Cell Type RNA - Adipocytes [nTPM]":"17.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.4","Single Cell Type RNA - Astrocytes [nTPM]":"36.9","Single Cell Type RNA - B-cells [nTPM]":"12.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"34.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"61.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"56.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"47.3","Single Cell Type RNA - Bipolar cells [nTPM]":"14.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"20.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"47.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.4","Single Cell Type RNA - dendritic cells [nTPM]":"22.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"22.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"14.6","Single Cell Type RNA - Early spermatids [nTPM]":"2.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"34.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.9","Single Cell Type RNA - Endothelial cells [nTPM]":"14.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"220.7","Single Cell Type RNA - Erythroid cells [nTPM]":"113.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.6","Single Cell Type RNA - Fibroblasts [nTPM]":"13.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"43.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"69.8","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"50.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.4","Single Cell Type RNA - Hepatocytes [nTPM]":"118.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.7","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"30.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.4","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"87.2","Single Cell Type RNA - Langerhans cells [nTPM]":"10.9","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"32.1","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"24.4","Single Cell Type RNA - monocytes [nTPM]":"10.6","Single Cell Type RNA - Muller glia cells [nTPM]":"12.5","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"30.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"84.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.9","Single Cell Type RNA - Paneth cells [nTPM]":"13.2","Single Cell Type RNA - Peritubular cells [nTPM]":"9.4","Single Cell Type RNA - Plasma cells [nTPM]":"10.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"88.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"27.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"66.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.5","Single Cell Type RNA - Spermatocytes [nTPM]":"3.1","Single Cell Type RNA - Spermatogonia [nTPM]":"9.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"72.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.8","Single Cell Type RNA - T-cells [nTPM]":"14.9","Single Cell Type RNA - Theca cells [nTPM]":"26.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.8","Single Cell Type RNA - Urothelial cells [nTPM]":"144.8"},{"Gene":"GCNT2","Gene synonym":["bA360O19.2","bA421M1.1","CCAT","GCNT5","IGNT","II","NACGT1","NAGCT1","ULG3"],"Ensembl":"ENSG00000111846","Gene description":"Glucosaminyl (N-acetyl) transferase 2 (I blood group)","Uniprot":["Q8N0V5"],"Chromosome":"6","Position":"10492223-10629368","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"prostate":"13.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"76.9","Endometrial ciliated cells":"79.1","Glandular and luminal cells":"105.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"44.2","Hep G2":"19.7","SK-MEL-30":"17.1","SuSa":"21.4"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"basal ganglia":"61.1"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026776"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"750000","Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA026776":"AB_1849573"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.6","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"0.7","Tissue RNA - appendix [nTPM]":"1.0","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"10.1","Tissue RNA - cerebellum [nTPM]":"2.5","Tissue RNA - cerebral cortex [nTPM]":"1.1","Tissue RNA - cervix [nTPM]":"4.2","Tissue RNA - choroid plexus [nTPM]":"4.5","Tissue RNA - colon [nTPM]":"3.6","Tissue RNA - duodenum [nTPM]":"5.2","Tissue RNA - endometrium 1 [nTPM]":"1.4","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"1.4","Tissue RNA - fallopian tube [nTPM]":"0.8","Tissue RNA - gallbladder [nTPM]":"1.5","Tissue RNA - heart muscle [nTPM]":"6.6","Tissue RNA - hippocampal formation [nTPM]":"0.8","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"5.7","Tissue RNA - liver [nTPM]":"5.1","Tissue RNA - lung [nTPM]":"3.9","Tissue RNA - lymph node [nTPM]":"1.8","Tissue RNA - medulla oblongata [nTPM]":"1.2","Tissue RNA - midbrain [nTPM]":"1.0","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"1.3","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"1.4","Tissue RNA - placenta [nTPM]":"2.6","Tissue RNA - pons [nTPM]":"1.4","Tissue RNA - prostate [nTPM]":"13.5","Tissue RNA - rectum [nTPM]":"2.0","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"4.2","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"1.4","Tissue RNA - small intestine [nTPM]":"5.8","Tissue RNA - smooth muscle [nTPM]":"1.6","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"1.5","Tissue RNA - stomach 1 [nTPM]":"5.9","Tissue RNA - testis [nTPM]":"2.5","Tissue RNA - thalamus [nTPM]":"0.9","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"1.2","Tissue RNA - tongue [nTPM]":"1.8","Tissue RNA - tonsil [nTPM]":"2.4","Tissue RNA - urinary bladder [nTPM]":"1.0","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"1.0","Cell RNA - A-431 [nTPM]":"6.3","Cell RNA - A549 [nTPM]":"4.9","Cell RNA - AF22 [nTPM]":"1.5","Cell RNA - AN3-CA [nTPM]":"4.8","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"9.6","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"4.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.5","Cell RNA - CACO-2 [nTPM]":"11.0","Cell RNA - CAPAN-2 [nTPM]":"5.2","Cell RNA - Daudi [nTPM]":"3.5","Cell RNA - EFO-21 [nTPM]":"44.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"3.2","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.4","Cell RNA - HBEC3-KT [nTPM]":"5.1","Cell RNA - HBF TERT88 [nTPM]":"2.9","Cell RNA - HDLM-2 [nTPM]":"3.1","Cell RNA - HEK 293 [nTPM]":"1.8","Cell RNA - HEL [nTPM]":"0.5","Cell RNA - HeLa [nTPM]":"2.6","Cell RNA - Hep G2 [nTPM]":"19.7","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"1.7","Cell RNA - HMC-1 [nTPM]":"4.7","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.5","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"2.4","Cell RNA - HUVEC TERT2 [nTPM]":"9.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"4.0","Cell RNA - NTERA-2 [nTPM]":"4.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"3.6","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"3.8","Cell RNA - RPMI-8226 [nTPM]":"6.0","Cell RNA - RPTEC TERT1 [nTPM]":"16.0","Cell RNA - RT4 [nTPM]":"2.9","Cell RNA - SCLC-21H [nTPM]":"4.0","Cell RNA - SH-SY5Y [nTPM]":"1.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"14.4","Cell RNA - SK-MEL-30 [nTPM]":"17.1","Cell RNA - SuSa [nTPM]":"21.4","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.8","Cell RNA - TIME [nTPM]":"6.4","Cell RNA - U-138 MG [nTPM]":"0.8","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"5.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"2.4","Cell RNA - U-87 MG [nTPM]":"0.8","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"2.3","Blood RNA - basophil [nTPM]":"1.9","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.8","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"0.7","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"2.5","Brain RNA - cerebral cortex [nTPM]":"1.1","Brain RNA - hippocampal formation [nTPM]":"0.8","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"1.2","Brain RNA - midbrain [nTPM]":"1.0","Brain RNA - pons [nTPM]":"1.4","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"0.9","Brain RNA - white matter [nTPM]":"1.0","Single Cell Type RNA - Adipocytes [nTPM]":"1.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"76.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"32.4","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"9.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"5.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"30.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"28.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.9","Single Cell Type RNA - dendritic cells [nTPM]":"6.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"2.9","Single Cell Type RNA - Early spermatids [nTPM]":"4.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"79.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.5","Single Cell Type RNA - Endothelial cells [nTPM]":"11.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"25.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"24.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.1","Single Cell Type RNA - Fibroblasts [nTPM]":"2.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"105.5","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.8","Single Cell Type RNA - Hepatocytes [nTPM]":"32.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.8","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.6","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"7.7","Single Cell Type RNA - Langerhans cells [nTPM]":"9.4","Single Cell Type RNA - Late spermatids [nTPM]":"8.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"7.8","Single Cell Type RNA - Melanocytes [nTPM]":"49.8","Single Cell Type RNA - Microglial cells [nTPM]":"52.5","Single Cell Type RNA - monocytes [nTPM]":"11.1","Single Cell Type RNA - Muller glia cells [nTPM]":"2.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.0","Single Cell Type RNA - Paneth cells [nTPM]":"11.9","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"44.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"27.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.2","Single Cell Type RNA - Spermatocytes [nTPM]":"6.2","Single Cell Type RNA - Spermatogonia [nTPM]":"27.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.9","Single Cell Type RNA - T-cells [nTPM]":"3.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.3","Single Cell Type RNA - Urothelial cells [nTPM]":"8.1"},{"Gene":"GFER","Gene synonym":["ALR","ERV1","HERV1","HPO1","HPO2","HSS"],"Ensembl":"ENSG00000127554","Gene description":"Growth factor, augmenter of liver regeneration","Uniprot":["P55789"],"Chromosome":"16","Position":"1984193-1987749","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Growth factor","Oxidoreductase"],"Disease involvement":["Cataract","Deafness","Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"183.7","Early spermatids":"168.7","Proximal enterocytes":"371.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041227","HPA063553"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Mitochondria","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA041227":"AB_10795538","HPA063553":"AB_2685038"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.06e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Tissue RNA - adipose tissue [nTPM]":"17.7","Tissue RNA - adrenal gland [nTPM]":"21.2","Tissue RNA - amygdala [nTPM]":"19.6","Tissue RNA - appendix [nTPM]":"13.8","Tissue RNA - basal ganglia [nTPM]":"19.0","Tissue RNA - bone marrow [nTPM]":"18.2","Tissue RNA - breast [nTPM]":"17.8","Tissue RNA - cerebellum [nTPM]":"21.6","Tissue RNA - cerebral cortex [nTPM]":"23.1","Tissue RNA - cervix [nTPM]":"14.2","Tissue RNA - choroid plexus [nTPM]":"17.9","Tissue RNA - colon [nTPM]":"32.8","Tissue RNA - duodenum [nTPM]":"42.7","Tissue RNA - endometrium 1 [nTPM]":"16.6","Tissue RNA - epididymis [nTPM]":"6.6","Tissue RNA - esophagus [nTPM]":"17.5","Tissue RNA - fallopian tube [nTPM]":"16.0","Tissue RNA - gallbladder [nTPM]":"13.5","Tissue RNA - heart muscle [nTPM]":"29.8","Tissue RNA - hippocampal formation [nTPM]":"19.0","Tissue RNA - hypothalamus [nTPM]":"19.7","Tissue RNA - kidney [nTPM]":"21.9","Tissue RNA - liver [nTPM]":"45.9","Tissue RNA - lung [nTPM]":"15.3","Tissue RNA - lymph node [nTPM]":"20.9","Tissue RNA - medulla oblongata [nTPM]":"21.5","Tissue RNA - midbrain [nTPM]":"21.1","Tissue RNA - ovary [nTPM]":"11.3","Tissue RNA - pancreas [nTPM]":"53.7","Tissue RNA - parathyroid gland [nTPM]":"29.6","Tissue RNA - pituitary gland [nTPM]":"18.1","Tissue RNA - placenta [nTPM]":"12.2","Tissue RNA - pons [nTPM]":"20.9","Tissue RNA - prostate [nTPM]":"19.6","Tissue RNA - rectum [nTPM]":"25.4","Tissue RNA - retina [nTPM]":"7.7","Tissue RNA - salivary gland [nTPM]":"28.8","Tissue RNA - seminal vesicle [nTPM]":"13.1","Tissue RNA - skeletal muscle [nTPM]":"40.9","Tissue RNA - skin 1 [nTPM]":"14.5","Tissue RNA - small intestine [nTPM]":"45.2","Tissue RNA - smooth muscle [nTPM]":"10.9","Tissue RNA - spinal cord [nTPM]":"18.8","Tissue RNA - spleen [nTPM]":"21.9","Tissue RNA - stomach 1 [nTPM]":"24.7","Tissue RNA - testis [nTPM]":"38.5","Tissue RNA - thalamus [nTPM]":"20.6","Tissue RNA - thymus [nTPM]":"10.5","Tissue RNA - thyroid gland [nTPM]":"15.9","Tissue RNA - tongue [nTPM]":"30.4","Tissue RNA - tonsil [nTPM]":"16.9","Tissue RNA - urinary bladder [nTPM]":"19.4","Tissue RNA - vagina [nTPM]":"12.8","Tissue RNA - white matter [nTPM]":"20.6","Cell RNA - A-431 [nTPM]":"27.2","Cell RNA - A549 [nTPM]":"44.1","Cell RNA - AF22 [nTPM]":"35.6","Cell RNA - AN3-CA [nTPM]":"29.2","Cell RNA - ASC diff [nTPM]":"14.7","Cell RNA - ASC TERT1 [nTPM]":"28.9","Cell RNA - BEWO [nTPM]":"43.5","Cell RNA - BJ [nTPM]":"28.6","Cell RNA - BJ hTERT+ [nTPM]":"31.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"44.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"35.6","Cell RNA - CACO-2 [nTPM]":"63.7","Cell RNA - CAPAN-2 [nTPM]":"46.1","Cell RNA - Daudi [nTPM]":"15.2","Cell RNA - EFO-21 [nTPM]":"39.7","Cell RNA - fHDF\/TERT166 [nTPM]":"24.2","Cell RNA - GAMG [nTPM]":"25.7","Cell RNA - HaCaT [nTPM]":"39.8","Cell RNA - HAP1 [nTPM]":"27.3","Cell RNA - HBEC3-KT [nTPM]":"42.4","Cell RNA - HBF TERT88 [nTPM]":"27.9","Cell RNA - HDLM-2 [nTPM]":"44.7","Cell RNA - HEK 293 [nTPM]":"46.6","Cell RNA - HEL [nTPM]":"20.9","Cell RNA - HeLa [nTPM]":"44.3","Cell RNA - Hep G2 [nTPM]":"73.4","Cell RNA - HHSteC [nTPM]":"26.6","Cell RNA - HL-60 [nTPM]":"32.1","Cell RNA - HMC-1 [nTPM]":"37.9","Cell RNA - HSkMC [nTPM]":"18.9","Cell RNA - hTCEpi [nTPM]":"32.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"38.8","Cell RNA - hTERT-HME1 [nTPM]":"34.6","Cell RNA - hTERT-RPE1 [nTPM]":"27.8","Cell RNA - HUVEC TERT2 [nTPM]":"21.1","Cell RNA - JURKAT [nTPM]":"32.7","Cell RNA - K-562 [nTPM]":"33.0","Cell RNA - Karpas-707 [nTPM]":"51.3","Cell RNA - LHCN-M2 [nTPM]":"32.6","Cell RNA - MCF7 [nTPM]":"66.1","Cell RNA - MOLT-4 [nTPM]":"34.9","Cell RNA - NB-4 [nTPM]":"33.9","Cell RNA - NTERA-2 [nTPM]":"54.9","Cell RNA - OE19 [nTPM]":"23.9","Cell RNA - PC-3 [nTPM]":"39.7","Cell RNA - REH [nTPM]":"74.5","Cell RNA - RH-30 [nTPM]":"26.8","Cell RNA - RPMI-8226 [nTPM]":"50.7","Cell RNA - RPTEC TERT1 [nTPM]":"45.5","Cell RNA - RT4 [nTPM]":"21.9","Cell RNA - SCLC-21H [nTPM]":"30.5","Cell RNA - SH-SY5Y [nTPM]":"28.9","Cell RNA - SiHa [nTPM]":"39.3","Cell RNA - SK-BR-3 [nTPM]":"91.2","Cell RNA - SK-MEL-30 [nTPM]":"34.5","Cell RNA - SuSa [nTPM]":"18.2","Cell RNA - T-47d [nTPM]":"43.4","Cell RNA - THP-1 [nTPM]":"33.6","Cell RNA - TIME [nTPM]":"19.1","Cell RNA - U-138 MG [nTPM]":"42.8","Cell RNA - U-2 OS [nTPM]":"45.0","Cell RNA - U-2197 [nTPM]":"24.0","Cell RNA - U-251 MG [nTPM]":"54.3","Cell RNA - U-266\/70 [nTPM]":"79.1","Cell RNA - U-266\/84 [nTPM]":"48.3","Cell RNA - U-698 [nTPM]":"45.7","Cell RNA - U-87 MG [nTPM]":"14.2","Cell RNA - U-937 [nTPM]":"21.5","Cell RNA - WM-115 [nTPM]":"36.7","Blood RNA - basophil [nTPM]":"3.8","Blood RNA - classical monocyte [nTPM]":"16.2","Blood RNA - eosinophil [nTPM]":"13.4","Blood RNA - gdT-cell [nTPM]":"11.2","Blood RNA - intermediate monocyte [nTPM]":"13.9","Blood RNA - MAIT T-cell [nTPM]":"11.4","Blood RNA - memory B-cell [nTPM]":"23.5","Blood RNA - memory CD4 T-cell [nTPM]":"14.9","Blood RNA - memory CD8 T-cell [nTPM]":"18.5","Blood RNA - myeloid DC [nTPM]":"11.6","Blood RNA - naive B-cell [nTPM]":"17.8","Blood RNA - naive CD4 T-cell [nTPM]":"13.6","Blood RNA - naive CD8 T-cell [nTPM]":"9.5","Blood RNA - neutrophil [nTPM]":"1.4","Blood RNA - NK-cell [nTPM]":"10.7","Blood RNA - non-classical monocyte [nTPM]":"17.4","Blood RNA - plasmacytoid DC [nTPM]":"5.1","Blood RNA - T-reg [nTPM]":"24.9","Blood RNA - total PBMC [nTPM]":"10.6","Brain RNA - amygdala [nTPM]":"19.6","Brain RNA - basal ganglia [nTPM]":"19.0","Brain RNA - cerebellum [nTPM]":"21.6","Brain RNA - cerebral cortex [nTPM]":"23.1","Brain RNA - hippocampal formation [nTPM]":"19.0","Brain RNA - hypothalamus [nTPM]":"19.7","Brain RNA - medulla oblongata [nTPM]":"21.5","Brain RNA - midbrain [nTPM]":"21.1","Brain RNA - pons [nTPM]":"20.9","Brain RNA - spinal cord [nTPM]":"18.8","Brain RNA - thalamus [nTPM]":"20.6","Brain RNA - white matter [nTPM]":"20.6","Single Cell Type RNA - Adipocytes [nTPM]":"18.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.7","Single Cell Type RNA - Astrocytes [nTPM]":"2.3","Single Cell Type RNA - B-cells [nTPM]":"32.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"19.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.6","Single Cell Type RNA - Bipolar cells [nTPM]":"10.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"32.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"27.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"16.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"43.4","Single Cell Type RNA - dendritic cells [nTPM]":"23.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"183.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"44.0","Single Cell Type RNA - Early spermatids [nTPM]":"168.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"24.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.4","Single Cell Type RNA - Endothelial cells [nTPM]":"17.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"27.2","Single Cell Type RNA - Erythroid cells [nTPM]":"17.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"80.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"57.8","Single Cell Type RNA - Fibroblasts [nTPM]":"17.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.7","Single Cell Type RNA - granulocytes [nTPM]":"12.7","Single Cell Type RNA - Granulosa cells [nTPM]":"22.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.7","Single Cell Type RNA - Hepatocytes [nTPM]":"59.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"45.9","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"60.3","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"39.3","Single Cell Type RNA - Langerhans cells [nTPM]":"24.8","Single Cell Type RNA - Late spermatids [nTPM]":"123.7","Single Cell Type RNA - Leydig cells [nTPM]":"17.4","Single Cell Type RNA - Macrophages [nTPM]":"24.7","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"39.6","Single Cell Type RNA - Muller glia cells [nTPM]":"12.6","Single Cell Type RNA - NK-cells [nTPM]":"39.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"57.3","Single Cell Type RNA - Paneth cells [nTPM]":"100.3","Single Cell Type RNA - Peritubular cells [nTPM]":"12.4","Single Cell Type RNA - Plasma cells [nTPM]":"39.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"21.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"371.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"84.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.5","Single Cell Type RNA - Spermatocytes [nTPM]":"41.9","Single Cell Type RNA - Spermatogonia [nTPM]":"26.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"37.5","Single Cell Type RNA - T-cells [nTPM]":"27.4","Single Cell Type RNA - Theca cells [nTPM]":"26.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"68.7","Single Cell Type RNA - Urothelial cells [nTPM]":"26.0"},{"Gene":"GFPT1","Gene synonym":["GFA","GFAT","GFAT1","GFPT"],"Ensembl":"ENSG00000198380","Gene description":"Glutamine--fructose-6-phosphate transaminase 1","Uniprot":["Q06210"],"Chromosome":"2","Position":"69319780-69387250","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Biological rhythms"],"Molecular function":["Aminotransferase","Transferase"],"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"184.2","Intestinal goblet cells":"244.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047240"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"93000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 27: Mucus-secreting cells - Mucin production","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":["Nucleoli fibrillar center"],"Antibody RRID":{"HPA047240":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.13e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Tissue RNA - adipose tissue [nTPM]":"31.2","Tissue RNA - adrenal gland [nTPM]":"17.9","Tissue RNA - amygdala [nTPM]":"6.6","Tissue RNA - appendix [nTPM]":"21.5","Tissue RNA - basal ganglia [nTPM]":"6.5","Tissue RNA - bone marrow [nTPM]":"15.0","Tissue RNA - breast [nTPM]":"22.4","Tissue RNA - cerebellum [nTPM]":"5.5","Tissue RNA - cerebral cortex [nTPM]":"7.1","Tissue RNA - cervix [nTPM]":"37.8","Tissue RNA - choroid plexus [nTPM]":"31.5","Tissue RNA - colon [nTPM]":"74.3","Tissue RNA - duodenum [nTPM]":"38.4","Tissue RNA - endometrium 1 [nTPM]":"15.6","Tissue RNA - epididymis [nTPM]":"41.6","Tissue RNA - esophagus [nTPM]":"16.4","Tissue RNA - fallopian tube [nTPM]":"24.3","Tissue RNA - gallbladder [nTPM]":"32.5","Tissue RNA - heart muscle [nTPM]":"24.8","Tissue RNA - hippocampal formation [nTPM]":"7.0","Tissue RNA - hypothalamus [nTPM]":"11.0","Tissue RNA - kidney [nTPM]":"21.6","Tissue RNA - liver [nTPM]":"23.1","Tissue RNA - lung [nTPM]":"17.0","Tissue RNA - lymph node [nTPM]":"10.6","Tissue RNA - medulla oblongata [nTPM]":"4.9","Tissue RNA - midbrain [nTPM]":"10.5","Tissue RNA - ovary [nTPM]":"12.0","Tissue RNA - pancreas [nTPM]":"33.7","Tissue RNA - parathyroid gland [nTPM]":"26.2","Tissue RNA - pituitary gland [nTPM]":"18.9","Tissue RNA - placenta [nTPM]":"36.0","Tissue RNA - pons [nTPM]":"10.8","Tissue RNA - prostate [nTPM]":"36.7","Tissue RNA - rectum [nTPM]":"76.6","Tissue RNA - retina [nTPM]":"10.4","Tissue RNA - salivary gland [nTPM]":"42.4","Tissue RNA - seminal vesicle [nTPM]":"25.9","Tissue RNA - skeletal muscle [nTPM]":"10.2","Tissue RNA - skin 1 [nTPM]":"6.0","Tissue RNA - small intestine [nTPM]":"41.2","Tissue RNA - smooth muscle [nTPM]":"23.2","Tissue RNA - spinal cord [nTPM]":"5.3","Tissue RNA - spleen [nTPM]":"9.5","Tissue RNA - stomach 1 [nTPM]":"64.3","Tissue RNA - testis [nTPM]":"46.6","Tissue RNA - thalamus [nTPM]":"8.0","Tissue RNA - thymus [nTPM]":"10.2","Tissue RNA - thyroid gland [nTPM]":"91.8","Tissue RNA - tongue [nTPM]":"13.9","Tissue RNA - tonsil [nTPM]":"15.9","Tissue RNA - urinary bladder [nTPM]":"21.8","Tissue RNA - vagina [nTPM]":"9.2","Tissue RNA - white matter [nTPM]":"6.8","Cell RNA - A-431 [nTPM]":"46.6","Cell RNA - A549 [nTPM]":"42.7","Cell RNA - AF22 [nTPM]":"34.7","Cell RNA - AN3-CA [nTPM]":"20.9","Cell RNA - ASC diff [nTPM]":"107.7","Cell RNA - ASC TERT1 [nTPM]":"75.8","Cell RNA - BEWO [nTPM]":"73.5","Cell RNA - BJ [nTPM]":"97.1","Cell RNA - BJ hTERT+ [nTPM]":"94.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"44.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"59.3","Cell RNA - CACO-2 [nTPM]":"109.5","Cell RNA - CAPAN-2 [nTPM]":"50.5","Cell RNA - Daudi [nTPM]":"31.7","Cell RNA - EFO-21 [nTPM]":"31.9","Cell RNA - fHDF\/TERT166 [nTPM]":"92.9","Cell RNA - GAMG [nTPM]":"61.4","Cell RNA - HaCaT [nTPM]":"22.6","Cell RNA - HAP1 [nTPM]":"47.1","Cell RNA - HBEC3-KT [nTPM]":"28.6","Cell RNA - HBF TERT88 [nTPM]":"73.6","Cell RNA - HDLM-2 [nTPM]":"38.4","Cell RNA - HEK 293 [nTPM]":"18.4","Cell RNA - HEL [nTPM]":"38.2","Cell RNA - HeLa [nTPM]":"25.0","Cell RNA - Hep G2 [nTPM]":"94.5","Cell RNA - HHSteC [nTPM]":"123.0","Cell RNA - HL-60 [nTPM]":"27.9","Cell RNA - HMC-1 [nTPM]":"17.9","Cell RNA - HSkMC [nTPM]":"47.8","Cell RNA - hTCEpi [nTPM]":"132.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"88.7","Cell RNA - hTERT-HME1 [nTPM]":"158.8","Cell RNA - hTERT-RPE1 [nTPM]":"55.5","Cell RNA - HUVEC TERT2 [nTPM]":"43.4","Cell RNA - JURKAT [nTPM]":"29.8","Cell RNA - K-562 [nTPM]":"34.8","Cell RNA - Karpas-707 [nTPM]":"58.3","Cell RNA - LHCN-M2 [nTPM]":"85.2","Cell RNA - MCF7 [nTPM]":"30.9","Cell RNA - MOLT-4 [nTPM]":"31.3","Cell RNA - NB-4 [nTPM]":"22.9","Cell RNA - NTERA-2 [nTPM]":"37.0","Cell RNA - OE19 [nTPM]":"116.7","Cell RNA - PC-3 [nTPM]":"27.4","Cell RNA - REH [nTPM]":"28.2","Cell RNA - RH-30 [nTPM]":"79.1","Cell RNA - RPMI-8226 [nTPM]":"18.3","Cell RNA - RPTEC TERT1 [nTPM]":"70.6","Cell RNA - RT4 [nTPM]":"42.0","Cell RNA - SCLC-21H [nTPM]":"25.2","Cell RNA - SH-SY5Y [nTPM]":"11.9","Cell RNA - SiHa [nTPM]":"35.2","Cell RNA - SK-BR-3 [nTPM]":"52.4","Cell RNA - SK-MEL-30 [nTPM]":"93.7","Cell RNA - SuSa [nTPM]":"73.5","Cell RNA - T-47d [nTPM]":"22.7","Cell RNA - THP-1 [nTPM]":"17.2","Cell RNA - TIME [nTPM]":"61.8","Cell RNA - U-138 MG [nTPM]":"37.2","Cell RNA - U-2 OS [nTPM]":"62.3","Cell RNA - U-2197 [nTPM]":"64.6","Cell RNA - U-251 MG [nTPM]":"47.5","Cell RNA - U-266\/70 [nTPM]":"39.5","Cell RNA - U-266\/84 [nTPM]":"32.2","Cell RNA - U-698 [nTPM]":"25.4","Cell RNA - U-87 MG [nTPM]":"65.7","Cell RNA - U-937 [nTPM]":"18.3","Cell RNA - WM-115 [nTPM]":"46.9","Blood RNA - basophil [nTPM]":"9.2","Blood RNA - classical monocyte [nTPM]":"3.5","Blood RNA - eosinophil [nTPM]":"4.9","Blood RNA - gdT-cell [nTPM]":"7.5","Blood RNA - intermediate monocyte [nTPM]":"4.3","Blood RNA - MAIT T-cell [nTPM]":"7.0","Blood RNA - memory B-cell [nTPM]":"6.4","Blood RNA - memory CD4 T-cell [nTPM]":"6.5","Blood RNA - memory CD8 T-cell [nTPM]":"8.3","Blood RNA - myeloid DC [nTPM]":"4.7","Blood RNA - naive B-cell [nTPM]":"3.6","Blood RNA - naive CD4 T-cell [nTPM]":"6.3","Blood RNA - naive CD8 T-cell [nTPM]":"6.2","Blood RNA - neutrophil [nTPM]":"1.2","Blood RNA - NK-cell [nTPM]":"5.2","Blood RNA - non-classical monocyte [nTPM]":"5.2","Blood RNA - plasmacytoid DC [nTPM]":"4.4","Blood RNA - T-reg [nTPM]":"5.0","Blood RNA - total PBMC [nTPM]":"4.2","Brain RNA - amygdala [nTPM]":"6.6","Brain RNA - basal ganglia [nTPM]":"6.5","Brain RNA - cerebellum [nTPM]":"5.5","Brain RNA - cerebral cortex [nTPM]":"7.1","Brain RNA - hippocampal formation [nTPM]":"7.0","Brain RNA - hypothalamus [nTPM]":"11.0","Brain RNA - medulla oblongata [nTPM]":"4.9","Brain RNA - midbrain [nTPM]":"10.5","Brain RNA - pons [nTPM]":"10.8","Brain RNA - spinal cord [nTPM]":"5.3","Brain RNA - thalamus [nTPM]":"8.0","Brain RNA - white matter [nTPM]":"6.8","Single Cell Type RNA - Adipocytes [nTPM]":"14.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"49.5","Single Cell Type RNA - Astrocytes [nTPM]":"15.7","Single Cell Type RNA - B-cells [nTPM]":"29.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"28.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"31.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.7","Single Cell Type RNA - Bipolar cells [nTPM]":"13.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"50.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"43.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"42.9","Single Cell Type RNA - Club cells [nTPM]":"54.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"28.6","Single Cell Type RNA - dendritic cells [nTPM]":"30.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"184.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"34.1","Single Cell Type RNA - Early spermatids [nTPM]":"123.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"54.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"54.1","Single Cell Type RNA - Endothelial cells [nTPM]":"17.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"75.1","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"49.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"89.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"70.3","Single Cell Type RNA - Fibroblasts [nTPM]":"37.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"110.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"60.0","Single Cell Type RNA - granulocytes [nTPM]":"24.1","Single Cell Type RNA - Granulosa cells [nTPM]":"19.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.9","Single Cell Type RNA - Hepatocytes [nTPM]":"53.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.0","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"56.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"244.0","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"10.0","Single Cell Type RNA - Langerhans cells [nTPM]":"31.4","Single Cell Type RNA - Late spermatids [nTPM]":"23.7","Single Cell Type RNA - Leydig cells [nTPM]":"23.3","Single Cell Type RNA - Macrophages [nTPM]":"16.0","Single Cell Type RNA - Melanocytes [nTPM]":"53.4","Single Cell Type RNA - Microglial cells [nTPM]":"27.2","Single Cell Type RNA - monocytes [nTPM]":"28.1","Single Cell Type RNA - Muller glia cells [nTPM]":"10.6","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"42.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"43.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"66.0","Single Cell Type RNA - Paneth cells [nTPM]":"83.3","Single Cell Type RNA - Peritubular cells [nTPM]":"28.2","Single Cell Type RNA - Plasma cells [nTPM]":"82.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"72.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"62.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"30.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"89.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.0","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"41.8","Single Cell Type RNA - Spermatocytes [nTPM]":"134.1","Single Cell Type RNA - Spermatogonia [nTPM]":"45.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"34.3","Single Cell Type RNA - T-cells [nTPM]":"33.4","Single Cell Type RNA - Theca cells [nTPM]":"15.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"135.3","Single Cell Type RNA - Urothelial cells [nTPM]":"56.3"},{"Gene":"GGT1","Gene synonym":["CD224","D22S672","D22S732","GGT"],"Ensembl":"ENSG00000100031","Gene description":"Gamma-glutamyltransferase 1","Uniprot":["P19440"],"Chromosome":"22","Position":"24594811-24629005","Protein class":["Candidate cardiovascular disease genes","CD markers","Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Glutathione biosynthesis","Lipid metabolism"],"Molecular function":["Acyltransferase","Hydrolase","Protease","Transferase"],"Disease involvement":["Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"174.8","liver":"115.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"80.1","Cholangiocytes":"48.6","Distal enterocytes":"54.1","Ductal cells":"82.6","Hepatocytes":"40.8","Proximal enterocytes":"111.7","Proximal tubular cells":"62.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"37.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"103.6","Karpas-707":"165.8","OE19":"169.5","RPMI-8226":"210.3","RPTEC TERT1":"203.2"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045635","HPA047534","HPA065444"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3600000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA045635":"AB_2679400","HPA047534":"AB_2680079","HPA065444":"AB_2685491"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.44e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.83e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.3","Tissue RNA - adrenal gland [nTPM]":"2.4","Tissue RNA - amygdala [nTPM]":"5.5","Tissue RNA - appendix [nTPM]":"6.4","Tissue RNA - basal ganglia [nTPM]":"6.7","Tissue RNA - bone marrow [nTPM]":"12.0","Tissue RNA - breast [nTPM]":"24.7","Tissue RNA - cerebellum [nTPM]":"7.0","Tissue RNA - cerebral cortex [nTPM]":"7.5","Tissue RNA - cervix [nTPM]":"28.7","Tissue RNA - choroid plexus [nTPM]":"5.1","Tissue RNA - colon [nTPM]":"20.3","Tissue RNA - duodenum [nTPM]":"84.7","Tissue RNA - endometrium 1 [nTPM]":"3.0","Tissue RNA - epididymis [nTPM]":"72.0","Tissue RNA - esophagus [nTPM]":"3.3","Tissue RNA - fallopian tube [nTPM]":"3.3","Tissue RNA - gallbladder [nTPM]":"47.1","Tissue RNA - heart muscle [nTPM]":"7.2","Tissue RNA - hippocampal formation [nTPM]":"5.1","Tissue RNA - hypothalamus [nTPM]":"5.1","Tissue RNA - kidney [nTPM]":"174.8","Tissue RNA - liver [nTPM]":"115.7","Tissue RNA - lung [nTPM]":"42.6","Tissue RNA - lymph node [nTPM]":"5.4","Tissue RNA - medulla oblongata [nTPM]":"7.2","Tissue RNA - midbrain [nTPM]":"6.6","Tissue RNA - ovary [nTPM]":"3.2","Tissue RNA - pancreas [nTPM]":"63.1","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"5.5","Tissue RNA - placenta [nTPM]":"2.4","Tissue RNA - pons [nTPM]":"7.8","Tissue RNA - prostate [nTPM]":"48.8","Tissue RNA - rectum [nTPM]":"11.0","Tissue RNA - retina [nTPM]":"1.6","Tissue RNA - salivary gland [nTPM]":"9.9","Tissue RNA - seminal vesicle [nTPM]":"21.6","Tissue RNA - skeletal muscle [nTPM]":"1.9","Tissue RNA - skin 1 [nTPM]":"4.1","Tissue RNA - small intestine [nTPM]":"80.4","Tissue RNA - smooth muscle [nTPM]":"2.2","Tissue RNA - spinal cord [nTPM]":"5.9","Tissue RNA - spleen [nTPM]":"13.3","Tissue RNA - stomach 1 [nTPM]":"31.3","Tissue RNA - testis [nTPM]":"18.4","Tissue RNA - thalamus [nTPM]":"7.1","Tissue RNA - thymus [nTPM]":"6.5","Tissue RNA - thyroid gland [nTPM]":"15.9","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"6.2","Tissue RNA - urinary bladder [nTPM]":"5.7","Tissue RNA - vagina [nTPM]":"4.3","Tissue RNA - white matter [nTPM]":"9.2","Cell RNA - A-431 [nTPM]":"1.0","Cell RNA - A549 [nTPM]":"79.7","Cell RNA - AF22 [nTPM]":"1.0","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.5","Cell RNA - BEWO [nTPM]":"2.2","Cell RNA - BJ [nTPM]":"0.5","Cell RNA - BJ hTERT+ [nTPM]":"1.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.0","Cell RNA - CACO-2 [nTPM]":"11.7","Cell RNA - CAPAN-2 [nTPM]":"18.3","Cell RNA - Daudi [nTPM]":"1.0","Cell RNA - EFO-21 [nTPM]":"16.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"14.8","Cell RNA - HaCaT [nTPM]":"11.0","Cell RNA - HAP1 [nTPM]":"6.2","Cell RNA - HBEC3-KT [nTPM]":"0.8","Cell RNA - HBF TERT88 [nTPM]":"0.5","Cell RNA - HDLM-2 [nTPM]":"103.6","Cell RNA - HEK 293 [nTPM]":"12.3","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"40.8","Cell RNA - Hep G2 [nTPM]":"64.3","Cell RNA - HHSteC [nTPM]":"5.5","Cell RNA - HL-60 [nTPM]":"1.5","Cell RNA - HMC-1 [nTPM]":"33.2","Cell RNA - HSkMC [nTPM]":"2.1","Cell RNA - hTCEpi [nTPM]":"0.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.5","Cell RNA - hTERT-HME1 [nTPM]":"1.7","Cell RNA - hTERT-RPE1 [nTPM]":"1.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.5","Cell RNA - JURKAT [nTPM]":"19.0","Cell RNA - K-562 [nTPM]":"8.4","Cell RNA - Karpas-707 [nTPM]":"165.8","Cell RNA - LHCN-M2 [nTPM]":"1.0","Cell RNA - MCF7 [nTPM]":"1.7","Cell RNA - MOLT-4 [nTPM]":"1.6","Cell RNA - NB-4 [nTPM]":"52.4","Cell RNA - NTERA-2 [nTPM]":"6.4","Cell RNA - OE19 [nTPM]":"169.5","Cell RNA - PC-3 [nTPM]":"0.7","Cell RNA - REH [nTPM]":"0.7","Cell RNA - RH-30 [nTPM]":"6.8","Cell RNA - RPMI-8226 [nTPM]":"210.3","Cell RNA - RPTEC TERT1 [nTPM]":"203.2","Cell RNA - RT4 [nTPM]":"2.9","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"1.2","Cell RNA - SiHa [nTPM]":"0.4","Cell RNA - SK-BR-3 [nTPM]":"33.3","Cell RNA - SK-MEL-30 [nTPM]":"0.8","Cell RNA - SuSa [nTPM]":"22.2","Cell RNA - T-47d [nTPM]":"32.4","Cell RNA - THP-1 [nTPM]":"39.6","Cell RNA - TIME [nTPM]":"6.4","Cell RNA - U-138 MG [nTPM]":"10.6","Cell RNA - U-2 OS [nTPM]":"9.3","Cell RNA - U-2197 [nTPM]":"46.6","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"48.2","Cell RNA - U-266\/84 [nTPM]":"18.4","Cell RNA - U-698 [nTPM]":"0.7","Cell RNA - U-87 MG [nTPM]":"19.0","Cell RNA - U-937 [nTPM]":"58.7","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"4.8","Blood RNA - classical monocyte [nTPM]":"12.3","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"6.0","Blood RNA - MAIT T-cell [nTPM]":"2.9","Blood RNA - memory B-cell [nTPM]":"2.2","Blood RNA - memory CD4 T-cell [nTPM]":"5.0","Blood RNA - memory CD8 T-cell [nTPM]":"2.4","Blood RNA - myeloid DC [nTPM]":"6.5","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"1.4","Blood RNA - neutrophil [nTPM]":"15.9","Blood RNA - NK-cell [nTPM]":"4.9","Blood RNA - non-classical monocyte [nTPM]":"4.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"6.5","Blood RNA - total PBMC [nTPM]":"5.6","Brain RNA - amygdala [nTPM]":"5.5","Brain RNA - basal ganglia [nTPM]":"6.7","Brain RNA - cerebellum [nTPM]":"7.0","Brain RNA - cerebral cortex [nTPM]":"7.5","Brain RNA - hippocampal formation [nTPM]":"5.1","Brain RNA - hypothalamus [nTPM]":"5.1","Brain RNA - medulla oblongata [nTPM]":"7.2","Brain RNA - midbrain [nTPM]":"6.6","Brain RNA - pons [nTPM]":"7.8","Brain RNA - spinal cord [nTPM]":"5.9","Brain RNA - thalamus [nTPM]":"7.1","Brain RNA - white matter [nTPM]":"9.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"80.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"22.8","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"2.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"48.6","Single Cell Type RNA - Club cells [nTPM]":"4.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"54.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"82.6","Single Cell Type RNA - Early spermatids [nTPM]":"1.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"5.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"3.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.1","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"40.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.4","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"2.5","Single Cell Type RNA - Langerhans cells [nTPM]":"1.7","Single Cell Type RNA - Late spermatids [nTPM]":"6.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"2.9","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"5.8","Single Cell Type RNA - Muller glia cells [nTPM]":"2.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.9","Single Cell Type RNA - Paneth cells [nTPM]":"20.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"12.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"111.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"62.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"4.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"GHSR","Gene synonym":[],"Ensembl":"ENSG00000121853","Gene description":"Growth hormone secretagogue receptor","Uniprot":["Q92847"],"Chromosome":"3","Position":"172443291-172448456","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"15.1"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"hippocampal formation":"3.8","hypothalamus":"15.1","thalamus":"3.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hypothalamus":"3.3"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.7","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"3.8","Tissue RNA - hypothalamus [nTPM]":"15.1","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"1.3","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"3.2","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.8","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"3.8","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.7","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"3.8","Brain RNA - hypothalamus [nTPM]":"15.1","Brain RNA - medulla oblongata [nTPM]":"1.3","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.8","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"3.8","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"GJA3","Gene synonym":["CX46","CZP3"],"Ensembl":"ENSG00000121743","Gene description":"Gap junction protein alpha 3","Uniprot":["Q9Y6H8"],"Chromosome":"13","Position":"20138255-20161052","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"7.8","parathyroid gland":"4.0","placenta":"2.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cardiomyocytes":"13.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"head and neck cancer":"1.3","melanoma":"3.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"4.4","CAPAN-2":"7.7","HL-60":"6.6","U-266\/84":"4.7"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014821"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014821":"AB_2669097"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"7.8","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.8","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"4.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"2.5","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"1.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"4.4","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"3.7","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"1.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.5","Cell RNA - BJ hTERT+ [nTPM]":"3.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.7","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"7.7","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"1.3","Cell RNA - GAMG [nTPM]":"1.2","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"2.5","Cell RNA - HBEC3-KT [nTPM]":"2.1","Cell RNA - HBF TERT88 [nTPM]":"0.5","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"1.9","Cell RNA - HEL [nTPM]":"1.8","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"6.6","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"1.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"2.8","Cell RNA - K-562 [nTPM]":"0.5","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"1.5","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"3.7","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.8","Cell RNA - THP-1 [nTPM]":"1.4","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"1.5","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"1.7","Cell RNA - U-266\/84 [nTPM]":"4.7","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"3.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"2.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"GJA5","Gene synonym":["CX40"],"Ensembl":"ENSG00000265107","Gene description":"Gap junction protein alpha 5","Uniprot":["P36382"],"Chromosome":"1","Position":"147756199-147773362","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Atrial fibrillation","Cardiomyopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"36.7","placenta":"85.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Cytotrophoblasts":"135.3","Extravillous trophoblasts":"345.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"SK-BR-3":"133.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013080","HPA071370"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB013080":"AB_2533263","HPA071370":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-2"},"Tissue RNA - adipose tissue [nTPM]":"18.6","Tissue RNA - adrenal gland [nTPM]":"2.2","Tissue RNA - amygdala [nTPM]":"2.5","Tissue RNA - appendix [nTPM]":"6.0","Tissue RNA - basal ganglia [nTPM]":"3.4","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"10.5","Tissue RNA - cerebellum [nTPM]":"2.4","Tissue RNA - cerebral cortex [nTPM]":"4.1","Tissue RNA - cervix [nTPM]":"5.5","Tissue RNA - choroid plexus [nTPM]":"2.6","Tissue RNA - colon [nTPM]":"4.7","Tissue RNA - duodenum [nTPM]":"3.4","Tissue RNA - endometrium 1 [nTPM]":"10.8","Tissue RNA - epididymis [nTPM]":"2.3","Tissue RNA - esophagus [nTPM]":"4.8","Tissue RNA - fallopian tube [nTPM]":"8.2","Tissue RNA - gallbladder [nTPM]":"6.3","Tissue RNA - heart muscle [nTPM]":"36.7","Tissue RNA - hippocampal formation [nTPM]":"2.4","Tissue RNA - hypothalamus [nTPM]":"2.2","Tissue RNA - kidney [nTPM]":"17.1","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"26.4","Tissue RNA - lymph node [nTPM]":"1.7","Tissue RNA - medulla oblongata [nTPM]":"2.8","Tissue RNA - midbrain [nTPM]":"2.6","Tissue RNA - ovary [nTPM]":"4.0","Tissue RNA - pancreas [nTPM]":"2.6","Tissue RNA - parathyroid gland [nTPM]":"3.4","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"85.4","Tissue RNA - pons [nTPM]":"2.5","Tissue RNA - prostate [nTPM]":"4.0","Tissue RNA - rectum [nTPM]":"4.1","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"1.6","Tissue RNA - seminal vesicle [nTPM]":"9.4","Tissue RNA - skeletal muscle [nTPM]":"2.1","Tissue RNA - skin 1 [nTPM]":"1.4","Tissue RNA - small intestine [nTPM]":"5.9","Tissue RNA - smooth muscle [nTPM]":"8.2","Tissue RNA - spinal cord [nTPM]":"2.6","Tissue RNA - spleen [nTPM]":"3.9","Tissue RNA - stomach 1 [nTPM]":"3.0","Tissue RNA - testis [nTPM]":"2.9","Tissue RNA - thalamus [nTPM]":"2.7","Tissue RNA - thymus [nTPM]":"0.6","Tissue RNA - thyroid gland [nTPM]":"5.3","Tissue RNA - tongue [nTPM]":"8.9","Tissue RNA - tonsil [nTPM]":"2.3","Tissue RNA - urinary bladder [nTPM]":"7.4","Tissue RNA - vagina [nTPM]":"3.8","Tissue RNA - white matter [nTPM]":"2.7","Cell RNA - A-431 [nTPM]":"1.8","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"5.7","Cell RNA - BJ [nTPM]":"4.4","Cell RNA - BJ hTERT+ [nTPM]":"2.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.5","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.7","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"9.3","Cell RNA - HBF TERT88 [nTPM]":"3.5","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"8.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"1.2","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"13.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"133.8","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"12.2","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.5","Brain RNA - basal ganglia [nTPM]":"3.4","Brain RNA - cerebellum [nTPM]":"2.4","Brain RNA - cerebral cortex [nTPM]":"4.1","Brain RNA - hippocampal formation [nTPM]":"2.4","Brain RNA - hypothalamus [nTPM]":"2.2","Brain RNA - medulla oblongata [nTPM]":"2.8","Brain RNA - midbrain [nTPM]":"2.6","Brain RNA - pons [nTPM]":"2.5","Brain RNA - spinal cord [nTPM]":"2.6","Brain RNA - thalamus [nTPM]":"2.7","Brain RNA - white matter [nTPM]":"2.7","Single Cell Type RNA - Adipocytes [nTPM]":"14.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"135.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"7.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"14.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"345.3","Single Cell Type RNA - Fibroblasts [nTPM]":"3.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"19.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"37.9","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"9.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.1","Single Cell Type RNA - Spermatocytes [nTPM]":"4.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"31.1","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"GJA8","Gene synonym":["CAE","CAE1","CX50","CZP1"],"Ensembl":"ENSG00000121634","Gene description":"Gap junction protein alpha 8","Uniprot":["P48165"],"Chromosome":"1","Position":"147902795-147909269","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"46","RNA tissue specific nTPM":{"testis":"5.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"14.6","Spermatocytes":"39.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014715","HPA062940"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014715":"AB_2732411","HPA062940":"AB_2732693"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"5.8","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.7","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"14.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"6.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"39.9","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"GJB1","Gene synonym":["CMTX","CMTX1","CX32"],"Ensembl":"ENSG00000169562","Gene description":"Gap junction protein beta 1","Uniprot":["P08034"],"Chromosome":"X","Position":"71212811-71225516","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Charcot-Marie-Tooth disease","Dejerine-Sottas syndrome","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"100.9","liver":"335.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"114.4","Hepatocytes":"286.4","Proximal enterocytes":"118.8","Proximal tubular cells":"68.9","Undifferentiated cells":"66.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"163.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Hep G2":"143.2","SK-MEL-30":"155.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB012994"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB012994":"AB_2533228"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.85e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"27.1","Tissue RNA - appendix [nTPM]":"3.7","Tissue RNA - basal ganglia [nTPM]":"63.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"6.4","Tissue RNA - cerebellum [nTPM]":"76.5","Tissue RNA - cerebral cortex [nTPM]":"37.6","Tissue RNA - cervix [nTPM]":"8.8","Tissue RNA - choroid plexus [nTPM]":"12.7","Tissue RNA - colon [nTPM]":"33.9","Tissue RNA - duodenum [nTPM]":"44.0","Tissue RNA - endometrium 1 [nTPM]":"1.7","Tissue RNA - epididymis [nTPM]":"22.5","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"27.4","Tissue RNA - gallbladder [nTPM]":"41.5","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"27.3","Tissue RNA - hypothalamus [nTPM]":"40.9","Tissue RNA - kidney [nTPM]":"42.9","Tissue RNA - liver [nTPM]":"335.7","Tissue RNA - lung [nTPM]":"2.4","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"90.6","Tissue RNA - midbrain [nTPM]":"64.4","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"83.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"76.0","Tissue RNA - prostate [nTPM]":"11.6","Tissue RNA - rectum [nTPM]":"23.8","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"37.7","Tissue RNA - seminal vesicle [nTPM]":"7.5","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"34.4","Tissue RNA - smooth muscle [nTPM]":"1.8","Tissue RNA - spinal cord [nTPM]":"50.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"16.4","Tissue RNA - testis [nTPM]":"10.2","Tissue RNA - thalamus [nTPM]":"56.9","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"100.9","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"25.5","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"143.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"5.6","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"5.1","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"155.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.6","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"27.1","Brain RNA - basal ganglia [nTPM]":"63.2","Brain RNA - cerebellum [nTPM]":"76.5","Brain RNA - cerebral cortex [nTPM]":"37.6","Brain RNA - hippocampal formation [nTPM]":"27.3","Brain RNA - hypothalamus [nTPM]":"40.9","Brain RNA - medulla oblongata [nTPM]":"90.6","Brain RNA - midbrain [nTPM]":"64.4","Brain RNA - pons [nTPM]":"76.0","Brain RNA - spinal cord [nTPM]":"50.0","Brain RNA - thalamus [nTPM]":"56.9","Brain RNA - white matter [nTPM]":"100.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"114.4","Single Cell Type RNA - Club cells [nTPM]":"2.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"50.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"34.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"8.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"58.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"29.0","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"286.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"29.4","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"51.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"32.3","Single Cell Type RNA - Paneth cells [nTPM]":"53.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"118.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"68.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"66.1","Single Cell Type RNA - Urothelial cells [nTPM]":"2.8"},{"Gene":"GJB2","Gene synonym":["CX26","DFNA3","DFNB1","NSRD1"],"Ensembl":"ENSG00000165474","Gene description":"Gap junction protein beta 2","Uniprot":["P29033"],"Chromosome":"13","Position":"20187463-20192938","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Ectodermal dysplasia","Ichthyosis","Non-syndromic deafness","Palmoplantar keratoderma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"328.1","esophagus":"812.1","vagina":"519.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"69.8","Basal respiratory cells":"237.4","Basal squamous epithelial cells":"55.8","Ionocytes":"50.8","Squamous epithelial cells":"160.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"447.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"CAPAN-2":"144.6","hTCEpi":"105.4","OE19":"76.9","RT4":"169.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013093","HPA014362"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB013093":"AB_2533903","HPA014362":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.45e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.25e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.90e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.53e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-3"},"Tissue RNA - adipose tissue [nTPM]":"2.0","Tissue RNA - adrenal gland [nTPM]":"0.7","Tissue RNA - amygdala [nTPM]":"1.3","Tissue RNA - appendix [nTPM]":"6.7","Tissue RNA - basal ganglia [nTPM]":"1.2","Tissue RNA - bone marrow [nTPM]":"3.8","Tissue RNA - breast [nTPM]":"3.7","Tissue RNA - cerebellum [nTPM]":"2.4","Tissue RNA - cerebral cortex [nTPM]":"3.1","Tissue RNA - cervix [nTPM]":"328.1","Tissue RNA - choroid plexus [nTPM]":"5.3","Tissue RNA - colon [nTPM]":"20.8","Tissue RNA - duodenum [nTPM]":"12.9","Tissue RNA - endometrium 1 [nTPM]":"2.9","Tissue RNA - epididymis [nTPM]":"3.4","Tissue RNA - esophagus [nTPM]":"812.1","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"14.0","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"1.1","Tissue RNA - hypothalamus [nTPM]":"1.7","Tissue RNA - kidney [nTPM]":"9.8","Tissue RNA - liver [nTPM]":"47.5","Tissue RNA - lung [nTPM]":"0.7","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"1.8","Tissue RNA - midbrain [nTPM]":"1.7","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"1.3","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"4.1","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"1.7","Tissue RNA - prostate [nTPM]":"1.2","Tissue RNA - rectum [nTPM]":"17.4","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"145.2","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"73.0","Tissue RNA - small intestine [nTPM]":"10.6","Tissue RNA - smooth muscle [nTPM]":"2.6","Tissue RNA - spinal cord [nTPM]":"1.7","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"8.1","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"7.6","Tissue RNA - thymus [nTPM]":"12.5","Tissue RNA - thyroid gland [nTPM]":"1.7","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"90.4","Tissue RNA - urinary bladder [nTPM]":"27.9","Tissue RNA - vagina [nTPM]":"519.8","Tissue RNA - white matter [nTPM]":"1.6","Cell RNA - A-431 [nTPM]":"8.7","Cell RNA - A549 [nTPM]":"0.6","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"2.9","Cell RNA - BEWO [nTPM]":"1.7","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"1.3","Cell RNA - CAPAN-2 [nTPM]":"144.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"1.1","Cell RNA - HaCaT [nTPM]":"28.9","Cell RNA - HAP1 [nTPM]":"5.3","Cell RNA - HBEC3-KT [nTPM]":"14.4","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"12.6","Cell RNA - HEK 293 [nTPM]":"1.8","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"5.1","Cell RNA - HSkMC [nTPM]":"2.4","Cell RNA - hTCEpi [nTPM]":"105.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.9","Cell RNA - hTERT-HME1 [nTPM]":"19.5","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"2.1","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"10.7","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"1.4","Cell RNA - MOLT-4 [nTPM]":"1.3","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"76.9","Cell RNA - PC-3 [nTPM]":"14.4","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"8.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"169.9","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"1.9","Cell RNA - T-47d [nTPM]":"2.2","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"2.5","Cell RNA - U-251 MG [nTPM]":"22.2","Cell RNA - U-266\/70 [nTPM]":"8.7","Cell RNA - U-266\/84 [nTPM]":"9.6","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"17.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"2.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.3","Brain RNA - basal ganglia [nTPM]":"1.2","Brain RNA - cerebellum [nTPM]":"2.4","Brain RNA - cerebral cortex [nTPM]":"3.1","Brain RNA - hippocampal formation [nTPM]":"1.1","Brain RNA - hypothalamus [nTPM]":"1.7","Brain RNA - medulla oblongata [nTPM]":"1.8","Brain RNA - midbrain [nTPM]":"1.7","Brain RNA - pons [nTPM]":"1.7","Brain RNA - spinal cord [nTPM]":"1.7","Brain RNA - thalamus [nTPM]":"7.6","Brain RNA - white matter [nTPM]":"1.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"69.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"237.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"55.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"37.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"28.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"4.4","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.5","Single Cell Type RNA - Endothelial cells [nTPM]":"1.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"1.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"25.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.1","Single Cell Type RNA - Ionocytes [nTPM]":"50.8","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"13.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"3.9","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"4.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.2","Single Cell Type RNA - Paneth cells [nTPM]":"13.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"2.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"160.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"28.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"25.0","Single Cell Type RNA - Urothelial cells [nTPM]":"21.7"},{"Gene":"GJB3","Gene synonym":["CX31","DFNA2","EKV"],"Ensembl":"ENSG00000188910","Gene description":"Gap junction protein beta 3","Uniprot":["O75712"],"Chromosome":"1","Position":"34781214-34786369","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness","Palmoplantar keratoderma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"esophagus":"77.8","skin 1":"145.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Basal keratinocytes":"138.4","Basal prostatic cells":"71.9","Basal respiratory cells":"43.6","Pancreatic endocrine cells":"119.8","Prostatic glandular cells":"63.4","Squamous epithelial cells":"91.9","Suprabasal keratinocytes":"170.6","Urothelial cells":"171.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"58.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"88.8","CAPAN-2":"121.7","HaCaT":"99.4","HBEC3-KT":"84.9","hTCEpi":"136.8","OE19":"54.2"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074472"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Vesicles","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA074472":"AB_2686694"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.56e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.56e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"1.3","Tissue RNA - appendix [nTPM]":"1.7","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"5.5","Tissue RNA - cerebellum [nTPM]":"1.1","Tissue RNA - cerebral cortex [nTPM]":"1.0","Tissue RNA - cervix [nTPM]":"8.9","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"4.2","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"2.8","Tissue RNA - esophagus [nTPM]":"77.8","Tissue RNA - fallopian tube [nTPM]":"1.1","Tissue RNA - gallbladder [nTPM]":"7.0","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.6","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.5","Tissue RNA - liver [nTPM]":"1.5","Tissue RNA - lung [nTPM]":"0.6","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"1.4","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"4.0","Tissue RNA - rectum [nTPM]":"5.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"8.9","Tissue RNA - seminal vesicle [nTPM]":"1.7","Tissue RNA - skeletal muscle [nTPM]":"0.6","Tissue RNA - skin 1 [nTPM]":"145.0","Tissue RNA - small intestine [nTPM]":"1.3","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"5.9","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"12.9","Tissue RNA - urinary bladder [nTPM]":"11.9","Tissue RNA - vagina [nTPM]":"26.4","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"88.8","Cell RNA - A549 [nTPM]":"2.6","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"121.7","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"11.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"99.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"84.9","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"5.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"136.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"35.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"4.8","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"54.2","Cell RNA - PC-3 [nTPM]":"22.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"40.8","Cell RNA - RT4 [nTPM]":"33.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"13.1","Cell RNA - SK-BR-3 [nTPM]":"0.9","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"1.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"5.7","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.3","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"1.1","Brain RNA - cerebral cortex [nTPM]":"1.0","Brain RNA - hippocampal formation [nTPM]":"0.6","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"138.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"71.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"43.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"16.5","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"15.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"14.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"1.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"1.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.8","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"12.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"119.8","Single Cell Type RNA - Paneth cells [nTPM]":"8.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"63.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"91.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"170.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.1","Single Cell Type RNA - Urothelial cells [nTPM]":"171.0"},{"Gene":"GJB4","Gene synonym":["CX30.3"],"Ensembl":"ENSG00000189433","Gene description":"Gap junction protein beta 4","Uniprot":["Q9NTQ9"],"Chromosome":"1","Position":"34759740-34762327","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Palmoplantar keratoderma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"skin 1":"43.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Basal prostatic cells":"31.1","Pancreatic endocrine cells":"37.0","Urothelial cells":"102.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"9.0","HaCaT":"12.2","HBEC3-KT":"8.3","hTCEpi":"5.7","OE19":"4.5","RPTEC TERT1":"4.8","RT4":"5.9"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055112","HPA073904"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA055112":"AB_2682699","HPA073904":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.48e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.24e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"2.6","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.7","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"5.5","Tissue RNA - esophagus [nTPM]":"2.3","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"4.8","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.8","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"43.1","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"2.3","Tissue RNA - urinary bladder [nTPM]":"7.9","Tissue RNA - vagina [nTPM]":"1.4","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"9.0","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"1.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"12.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"8.3","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"1.8","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"5.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"4.5","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"4.8","Cell RNA - RT4 [nTPM]":"5.9","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.5","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"31.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"5.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"37.0","Single Cell Type RNA - Paneth cells [nTPM]":"1.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"102.6"},{"Gene":"GK","Gene synonym":["GK1","GKD"],"Ensembl":"ENSG00000198814","Gene description":"Glycerol kinase","Uniprot":["P32189"],"Chromosome":"X","Position":"30653359-30731462","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Glycerol metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"90.7","kidney":"107.7","liver":"79.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"139.2","Macrophages":"133.4","Proximal enterocytes":"144.2","Proximal tubular cells":"161.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"neutrophil":"178.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"178.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+":"37.4","Hep G2":"46.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060687"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA060687":"AB_2684343"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.41e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.24e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-3"},"Tissue RNA - adipose tissue [nTPM]":"8.8","Tissue RNA - adrenal gland [nTPM]":"9.8","Tissue RNA - amygdala [nTPM]":"3.1","Tissue RNA - appendix [nTPM]":"51.5","Tissue RNA - basal ganglia [nTPM]":"2.8","Tissue RNA - bone marrow [nTPM]":"6.6","Tissue RNA - breast [nTPM]":"4.8","Tissue RNA - cerebellum [nTPM]":"3.7","Tissue RNA - cerebral cortex [nTPM]":"17.2","Tissue RNA - cervix [nTPM]":"4.8","Tissue RNA - choroid plexus [nTPM]":"8.4","Tissue RNA - colon [nTPM]":"13.0","Tissue RNA - duodenum [nTPM]":"86.6","Tissue RNA - endometrium 1 [nTPM]":"3.6","Tissue RNA - epididymis [nTPM]":"12.3","Tissue RNA - esophagus [nTPM]":"9.6","Tissue RNA - fallopian tube [nTPM]":"7.7","Tissue RNA - gallbladder [nTPM]":"23.8","Tissue RNA - heart muscle [nTPM]":"4.8","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"4.1","Tissue RNA - kidney [nTPM]":"107.7","Tissue RNA - liver [nTPM]":"79.2","Tissue RNA - lung [nTPM]":"19.7","Tissue RNA - lymph node [nTPM]":"10.6","Tissue RNA - medulla oblongata [nTPM]":"7.2","Tissue RNA - midbrain [nTPM]":"4.2","Tissue RNA - ovary [nTPM]":"2.6","Tissue RNA - pancreas [nTPM]":"4.5","Tissue RNA - parathyroid gland [nTPM]":"14.0","Tissue RNA - pituitary gland [nTPM]":"5.4","Tissue RNA - placenta [nTPM]":"8.2","Tissue RNA - pons [nTPM]":"6.8","Tissue RNA - prostate [nTPM]":"3.6","Tissue RNA - rectum [nTPM]":"10.9","Tissue RNA - retina [nTPM]":"10.3","Tissue RNA - salivary gland [nTPM]":"11.2","Tissue RNA - seminal vesicle [nTPM]":"2.2","Tissue RNA - skeletal muscle [nTPM]":"2.6","Tissue RNA - skin 1 [nTPM]":"6.3","Tissue RNA - small intestine [nTPM]":"90.7","Tissue RNA - smooth muscle [nTPM]":"4.4","Tissue RNA - spinal cord [nTPM]":"3.6","Tissue RNA - spleen [nTPM]":"10.1","Tissue RNA - stomach 1 [nTPM]":"6.2","Tissue RNA - testis [nTPM]":"2.9","Tissue RNA - thalamus [nTPM]":"14.5","Tissue RNA - thymus [nTPM]":"5.4","Tissue RNA - thyroid gland [nTPM]":"6.6","Tissue RNA - tongue [nTPM]":"3.1","Tissue RNA - tonsil [nTPM]":"14.5","Tissue RNA - urinary bladder [nTPM]":"30.2","Tissue RNA - vagina [nTPM]":"2.7","Tissue RNA - white matter [nTPM]":"8.0","Cell RNA - A-431 [nTPM]":"4.5","Cell RNA - A549 [nTPM]":"3.5","Cell RNA - AF22 [nTPM]":"4.5","Cell RNA - AN3-CA [nTPM]":"7.7","Cell RNA - ASC diff [nTPM]":"2.7","Cell RNA - ASC TERT1 [nTPM]":"10.4","Cell RNA - BEWO [nTPM]":"1.8","Cell RNA - BJ [nTPM]":"10.6","Cell RNA - BJ hTERT+ [nTPM]":"37.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.6","Cell RNA - CACO-2 [nTPM]":"5.8","Cell RNA - CAPAN-2 [nTPM]":"4.1","Cell RNA - Daudi [nTPM]":"12.6","Cell RNA - EFO-21 [nTPM]":"1.7","Cell RNA - fHDF\/TERT166 [nTPM]":"4.1","Cell RNA - GAMG [nTPM]":"6.9","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"8.5","Cell RNA - HBEC3-KT [nTPM]":"3.5","Cell RNA - HBF TERT88 [nTPM]":"10.1","Cell RNA - HDLM-2 [nTPM]":"8.2","Cell RNA - HEK 293 [nTPM]":"9.6","Cell RNA - HEL [nTPM]":"7.5","Cell RNA - HeLa [nTPM]":"6.6","Cell RNA - Hep G2 [nTPM]":"46.4","Cell RNA - HHSteC [nTPM]":"17.2","Cell RNA - HL-60 [nTPM]":"14.2","Cell RNA - HMC-1 [nTPM]":"15.4","Cell RNA - HSkMC [nTPM]":"6.3","Cell RNA - hTCEpi [nTPM]":"4.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"24.2","Cell RNA - hTERT-HME1 [nTPM]":"22.3","Cell RNA - hTERT-RPE1 [nTPM]":"1.9","Cell RNA - HUVEC TERT2 [nTPM]":"6.0","Cell RNA - JURKAT [nTPM]":"9.6","Cell RNA - K-562 [nTPM]":"4.0","Cell RNA - Karpas-707 [nTPM]":"17.3","Cell RNA - LHCN-M2 [nTPM]":"2.1","Cell RNA - MCF7 [nTPM]":"6.2","Cell RNA - MOLT-4 [nTPM]":"11.0","Cell RNA - NB-4 [nTPM]":"14.6","Cell RNA - NTERA-2 [nTPM]":"7.5","Cell RNA - OE19 [nTPM]":"4.9","Cell RNA - PC-3 [nTPM]":"4.0","Cell RNA - REH [nTPM]":"15.0","Cell RNA - RH-30 [nTPM]":"7.1","Cell RNA - RPMI-8226 [nTPM]":"13.1","Cell RNA - RPTEC TERT1 [nTPM]":"5.7","Cell RNA - RT4 [nTPM]":"14.8","Cell RNA - SCLC-21H [nTPM]":"4.8","Cell RNA - SH-SY5Y [nTPM]":"6.1","Cell RNA - SiHa [nTPM]":"9.4","Cell RNA - SK-BR-3 [nTPM]":"9.4","Cell RNA - SK-MEL-30 [nTPM]":"21.5","Cell RNA - SuSa [nTPM]":"4.5","Cell RNA - T-47d [nTPM]":"10.6","Cell RNA - THP-1 [nTPM]":"10.1","Cell RNA - TIME [nTPM]":"2.3","Cell RNA - U-138 MG [nTPM]":"5.5","Cell RNA - U-2 OS [nTPM]":"2.3","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"4.9","Cell RNA - U-266\/70 [nTPM]":"9.1","Cell RNA - U-266\/84 [nTPM]":"10.7","Cell RNA - U-698 [nTPM]":"12.5","Cell RNA - U-87 MG [nTPM]":"9.5","Cell RNA - U-937 [nTPM]":"9.1","Cell RNA - WM-115 [nTPM]":"5.6","Blood RNA - basophil [nTPM]":"5.0","Blood RNA - classical monocyte [nTPM]":"22.8","Blood RNA - eosinophil [nTPM]":"7.9","Blood RNA - gdT-cell [nTPM]":"1.7","Blood RNA - intermediate monocyte [nTPM]":"7.2","Blood RNA - MAIT T-cell [nTPM]":"1.3","Blood RNA - memory B-cell [nTPM]":"3.1","Blood RNA - memory CD4 T-cell [nTPM]":"3.1","Blood RNA - memory CD8 T-cell [nTPM]":"2.2","Blood RNA - myeloid DC [nTPM]":"14.2","Blood RNA - naive B-cell [nTPM]":"5.6","Blood RNA - naive CD4 T-cell [nTPM]":"1.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"178.4","Blood RNA - NK-cell [nTPM]":"4.8","Blood RNA - non-classical monocyte [nTPM]":"9.1","Blood RNA - plasmacytoid DC [nTPM]":"4.2","Blood RNA - T-reg [nTPM]":"11.5","Blood RNA - total PBMC [nTPM]":"6.2","Brain RNA - amygdala [nTPM]":"3.1","Brain RNA - basal ganglia [nTPM]":"2.8","Brain RNA - cerebellum [nTPM]":"3.7","Brain RNA - cerebral cortex [nTPM]":"17.2","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"4.1","Brain RNA - medulla oblongata [nTPM]":"7.2","Brain RNA - midbrain [nTPM]":"4.2","Brain RNA - pons [nTPM]":"6.8","Brain RNA - spinal cord [nTPM]":"3.6","Brain RNA - thalamus [nTPM]":"14.5","Brain RNA - white matter [nTPM]":"8.0","Single Cell Type RNA - Adipocytes [nTPM]":"2.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.4","Single Cell Type RNA - Astrocytes [nTPM]":"19.6","Single Cell Type RNA - B-cells [nTPM]":"15.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"3.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"22.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - dendritic cells [nTPM]":"5.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"54.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"21.9","Single Cell Type RNA - Early spermatids [nTPM]":"61.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.7","Single Cell Type RNA - Endothelial cells [nTPM]":"3.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.1","Single Cell Type RNA - Erythroid cells [nTPM]":"6.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"41.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.1","Single Cell Type RNA - Fibroblasts [nTPM]":"12.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.7","Single Cell Type RNA - granulocytes [nTPM]":"14.5","Single Cell Type RNA - Granulosa cells [nTPM]":"6.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"38.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"34.8","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"26.6","Single Cell Type RNA - Langerhans cells [nTPM]":"139.2","Single Cell Type RNA - Late spermatids [nTPM]":"29.9","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"133.4","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"42.6","Single Cell Type RNA - Muller glia cells [nTPM]":"29.1","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"28.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.6","Single Cell Type RNA - Paneth cells [nTPM]":"39.9","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"12.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"144.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"161.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"47.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.0","Single Cell Type RNA - Spermatocytes [nTPM]":"15.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"15.7","Single Cell Type RNA - Theca cells [nTPM]":"3.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.0","Single Cell Type RNA - Urothelial cells [nTPM]":"26.8"},{"Gene":"GLA","Gene synonym":["GALA"],"Ensembl":"ENSG00000102393","Gene description":"Galactosidase alpha","Uniprot":["P06280"],"Chromosome":"X","Position":"101393273-101408012","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"229.9","Plasma cells":"171.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"328.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000237","HPA000966"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1300000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA000237":"AB_1078968","HPA000966":"AB_1078969"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.62e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.16e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Tissue RNA - adipose tissue [nTPM]":"15.6","Tissue RNA - adrenal gland [nTPM]":"21.5","Tissue RNA - amygdala [nTPM]":"5.2","Tissue RNA - appendix [nTPM]":"12.7","Tissue RNA - basal ganglia [nTPM]":"5.4","Tissue RNA - bone marrow [nTPM]":"25.1","Tissue RNA - breast [nTPM]":"26.7","Tissue RNA - cerebellum [nTPM]":"6.6","Tissue RNA - cerebral cortex [nTPM]":"6.9","Tissue RNA - cervix [nTPM]":"13.8","Tissue RNA - choroid plexus [nTPM]":"6.2","Tissue RNA - colon [nTPM]":"13.0","Tissue RNA - duodenum [nTPM]":"22.4","Tissue RNA - endometrium 1 [nTPM]":"10.9","Tissue RNA - epididymis [nTPM]":"17.5","Tissue RNA - esophagus [nTPM]":"9.3","Tissue RNA - fallopian tube [nTPM]":"15.2","Tissue RNA - gallbladder [nTPM]":"11.8","Tissue RNA - heart muscle [nTPM]":"9.9","Tissue RNA - hippocampal formation [nTPM]":"5.6","Tissue RNA - hypothalamus [nTPM]":"6.2","Tissue RNA - kidney [nTPM]":"15.6","Tissue RNA - liver [nTPM]":"12.7","Tissue RNA - lung [nTPM]":"17.2","Tissue RNA - lymph node [nTPM]":"13.2","Tissue RNA - medulla oblongata [nTPM]":"7.0","Tissue RNA - midbrain [nTPM]":"7.3","Tissue RNA - ovary [nTPM]":"9.2","Tissue RNA - pancreas [nTPM]":"6.7","Tissue RNA - parathyroid gland [nTPM]":"31.7","Tissue RNA - pituitary gland [nTPM]":"9.9","Tissue RNA - placenta [nTPM]":"22.1","Tissue RNA - pons [nTPM]":"7.3","Tissue RNA - prostate [nTPM]":"7.9","Tissue RNA - rectum [nTPM]":"15.3","Tissue RNA - retina [nTPM]":"6.9","Tissue RNA - salivary gland [nTPM]":"10.0","Tissue RNA - seminal vesicle [nTPM]":"39.3","Tissue RNA - skeletal muscle [nTPM]":"6.2","Tissue RNA - skin 1 [nTPM]":"9.2","Tissue RNA - small intestine [nTPM]":"13.5","Tissue RNA - smooth muscle [nTPM]":"15.4","Tissue RNA - spinal cord [nTPM]":"6.5","Tissue RNA - spleen [nTPM]":"13.2","Tissue RNA - stomach 1 [nTPM]":"9.3","Tissue RNA - testis [nTPM]":"3.8","Tissue RNA - thalamus [nTPM]":"6.9","Tissue RNA - thymus [nTPM]":"12.0","Tissue RNA - thyroid gland [nTPM]":"7.9","Tissue RNA - tongue [nTPM]":"6.5","Tissue RNA - tonsil [nTPM]":"15.6","Tissue RNA - urinary bladder [nTPM]":"14.7","Tissue RNA - vagina [nTPM]":"9.1","Tissue RNA - white matter [nTPM]":"8.1","Cell RNA - A-431 [nTPM]":"30.5","Cell RNA - A549 [nTPM]":"117.9","Cell RNA - AF22 [nTPM]":"30.8","Cell RNA - AN3-CA [nTPM]":"31.9","Cell RNA - ASC diff [nTPM]":"68.9","Cell RNA - ASC TERT1 [nTPM]":"26.8","Cell RNA - BEWO [nTPM]":"13.8","Cell RNA - BJ [nTPM]":"34.1","Cell RNA - BJ hTERT+ [nTPM]":"51.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"63.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"176.3","Cell RNA - CACO-2 [nTPM]":"64.7","Cell RNA - CAPAN-2 [nTPM]":"45.9","Cell RNA - Daudi [nTPM]":"33.6","Cell RNA - EFO-21 [nTPM]":"70.0","Cell RNA - fHDF\/TERT166 [nTPM]":"35.3","Cell RNA - GAMG [nTPM]":"151.8","Cell RNA - HaCaT [nTPM]":"70.3","Cell RNA - HAP1 [nTPM]":"65.9","Cell RNA - HBEC3-KT [nTPM]":"38.3","Cell RNA - HBF TERT88 [nTPM]":"53.8","Cell RNA - HDLM-2 [nTPM]":"19.3","Cell RNA - HEK 293 [nTPM]":"47.1","Cell RNA - HEL [nTPM]":"18.3","Cell RNA - HeLa [nTPM]":"87.9","Cell RNA - Hep G2 [nTPM]":"78.4","Cell RNA - HHSteC [nTPM]":"19.2","Cell RNA - HL-60 [nTPM]":"26.7","Cell RNA - HMC-1 [nTPM]":"328.1","Cell RNA - HSkMC [nTPM]":"24.3","Cell RNA - hTCEpi [nTPM]":"11.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"72.9","Cell RNA - hTERT-HME1 [nTPM]":"21.6","Cell RNA - hTERT-RPE1 [nTPM]":"17.4","Cell RNA - HUVEC TERT2 [nTPM]":"50.9","Cell RNA - JURKAT [nTPM]":"18.2","Cell RNA - K-562 [nTPM]":"28.6","Cell RNA - Karpas-707 [nTPM]":"71.2","Cell RNA - LHCN-M2 [nTPM]":"60.8","Cell RNA - MCF7 [nTPM]":"52.3","Cell RNA - MOLT-4 [nTPM]":"24.4","Cell RNA - NB-4 [nTPM]":"53.7","Cell RNA - NTERA-2 [nTPM]":"48.2","Cell RNA - OE19 [nTPM]":"72.5","Cell RNA - PC-3 [nTPM]":"46.4","Cell RNA - REH [nTPM]":"18.2","Cell RNA - RH-30 [nTPM]":"39.5","Cell RNA - RPMI-8226 [nTPM]":"81.5","Cell RNA - RPTEC TERT1 [nTPM]":"95.1","Cell RNA - RT4 [nTPM]":"61.9","Cell RNA - SCLC-21H [nTPM]":"11.5","Cell RNA - SH-SY5Y [nTPM]":"19.4","Cell RNA - SiHa [nTPM]":"78.6","Cell RNA - SK-BR-3 [nTPM]":"34.6","Cell RNA - SK-MEL-30 [nTPM]":"30.9","Cell RNA - SuSa [nTPM]":"54.4","Cell RNA - T-47d [nTPM]":"15.2","Cell RNA - THP-1 [nTPM]":"51.2","Cell RNA - TIME [nTPM]":"29.9","Cell RNA - U-138 MG [nTPM]":"20.7","Cell RNA - U-2 OS [nTPM]":"23.8","Cell RNA - U-2197 [nTPM]":"52.6","Cell RNA - U-251 MG [nTPM]":"27.0","Cell RNA - U-266\/70 [nTPM]":"23.0","Cell RNA - U-266\/84 [nTPM]":"26.3","Cell RNA - U-698 [nTPM]":"25.4","Cell RNA - U-87 MG [nTPM]":"36.9","Cell RNA - U-937 [nTPM]":"39.9","Cell RNA - WM-115 [nTPM]":"23.1","Blood RNA - basophil [nTPM]":"22.5","Blood RNA - classical monocyte [nTPM]":"37.3","Blood RNA - eosinophil [nTPM]":"11.9","Blood RNA - gdT-cell [nTPM]":"6.9","Blood RNA - intermediate monocyte [nTPM]":"38.5","Blood RNA - MAIT T-cell [nTPM]":"9.0","Blood RNA - memory B-cell [nTPM]":"8.8","Blood RNA - memory CD4 T-cell [nTPM]":"5.6","Blood RNA - memory CD8 T-cell [nTPM]":"8.8","Blood RNA - myeloid DC [nTPM]":"29.8","Blood RNA - naive B-cell [nTPM]":"9.0","Blood RNA - naive CD4 T-cell [nTPM]":"5.6","Blood RNA - naive CD8 T-cell [nTPM]":"6.9","Blood RNA - neutrophil [nTPM]":"21.6","Blood RNA - NK-cell [nTPM]":"5.6","Blood RNA - non-classical monocyte [nTPM]":"40.6","Blood RNA - plasmacytoid DC [nTPM]":"10.9","Blood RNA - T-reg [nTPM]":"7.3","Blood RNA - total PBMC [nTPM]":"20.4","Brain RNA - amygdala [nTPM]":"5.2","Brain RNA - basal ganglia [nTPM]":"5.4","Brain RNA - cerebellum [nTPM]":"6.6","Brain RNA - cerebral cortex [nTPM]":"6.9","Brain RNA - hippocampal formation [nTPM]":"5.6","Brain RNA - hypothalamus [nTPM]":"6.2","Brain RNA - medulla oblongata [nTPM]":"7.0","Brain RNA - midbrain [nTPM]":"7.3","Brain RNA - pons [nTPM]":"7.3","Brain RNA - spinal cord [nTPM]":"6.5","Brain RNA - thalamus [nTPM]":"6.9","Brain RNA - white matter [nTPM]":"8.1","Single Cell Type RNA - Adipocytes [nTPM]":"31.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.2","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"65.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"23.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"45.5","Single Cell Type RNA - Bipolar cells [nTPM]":"4.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"34.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"19.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"38.4","Single Cell Type RNA - dendritic cells [nTPM]":"25.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"26.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"22.5","Single Cell Type RNA - Early spermatids [nTPM]":"3.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"57.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.5","Single Cell Type RNA - Endothelial cells [nTPM]":"30.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"33.9","Single Cell Type RNA - Erythroid cells [nTPM]":"12.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.3","Single Cell Type RNA - Fibroblasts [nTPM]":"66.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"39.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"97.6","Single Cell Type RNA - granulocytes [nTPM]":"31.0","Single Cell Type RNA - Granulosa cells [nTPM]":"9.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.9","Single Cell Type RNA - Hepatocytes [nTPM]":"7.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"93.0","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.9","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"28.5","Single Cell Type RNA - Langerhans cells [nTPM]":"229.9","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"11.1","Single Cell Type RNA - Macrophages [nTPM]":"115.7","Single Cell Type RNA - Melanocytes [nTPM]":"88.9","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"30.3","Single Cell Type RNA - Muller glia cells [nTPM]":"17.5","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.4","Single Cell Type RNA - Paneth cells [nTPM]":"25.3","Single Cell Type RNA - Peritubular cells [nTPM]":"18.0","Single Cell Type RNA - Plasma cells [nTPM]":"171.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"30.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"70.8","Single Cell Type RNA - Spermatocytes [nTPM]":"6.4","Single Cell Type RNA - Spermatogonia [nTPM]":"5.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"31.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"23.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"75.5","Single Cell Type RNA - T-cells [nTPM]":"33.2","Single Cell Type RNA - Theca cells [nTPM]":"19.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.2","Single Cell Type RNA - Urothelial cells [nTPM]":"27.9"},{"Gene":"GLB1","Gene synonym":["EBP","ELNR1"],"Ensembl":"ENSG00000170266","Gene description":"Galactosidase beta 1","Uniprot":["P16278"],"Chromosome":"3","Position":"32996609-33097202","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant","Gangliosidosis","Mucopolysaccharidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"857.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB008382","HPA040610","HPA069503"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2700000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB008382":"AB_590642","HPA040610":"AB_2677039","HPA069503":"AB_2686142"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.66e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.61e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.14e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-2"},"Tissue RNA - adipose tissue [nTPM]":"22.0","Tissue RNA - adrenal gland [nTPM]":"36.1","Tissue RNA - amygdala [nTPM]":"12.1","Tissue RNA - appendix [nTPM]":"27.8","Tissue RNA - basal ganglia [nTPM]":"13.0","Tissue RNA - bone marrow [nTPM]":"21.9","Tissue RNA - breast [nTPM]":"20.5","Tissue RNA - cerebellum [nTPM]":"12.5","Tissue RNA - cerebral cortex [nTPM]":"14.8","Tissue RNA - cervix [nTPM]":"33.4","Tissue RNA - choroid plexus [nTPM]":"16.0","Tissue RNA - colon [nTPM]":"43.5","Tissue RNA - duodenum [nTPM]":"43.0","Tissue RNA - endometrium 1 [nTPM]":"21.9","Tissue RNA - epididymis [nTPM]":"103.6","Tissue RNA - esophagus [nTPM]":"15.4","Tissue RNA - fallopian tube [nTPM]":"28.2","Tissue RNA - gallbladder [nTPM]":"32.0","Tissue RNA - heart muscle [nTPM]":"15.5","Tissue RNA - hippocampal formation [nTPM]":"12.5","Tissue RNA - hypothalamus [nTPM]":"14.8","Tissue RNA - kidney [nTPM]":"46.0","Tissue RNA - liver [nTPM]":"48.2","Tissue RNA - lung [nTPM]":"42.7","Tissue RNA - lymph node [nTPM]":"25.8","Tissue RNA - medulla oblongata [nTPM]":"14.3","Tissue RNA - midbrain [nTPM]":"12.9","Tissue RNA - ovary [nTPM]":"21.4","Tissue RNA - pancreas [nTPM]":"30.8","Tissue RNA - parathyroid gland [nTPM]":"59.4","Tissue RNA - pituitary gland [nTPM]":"18.5","Tissue RNA - placenta [nTPM]":"53.8","Tissue RNA - pons [nTPM]":"15.4","Tissue RNA - prostate [nTPM]":"23.2","Tissue RNA - rectum [nTPM]":"45.6","Tissue RNA - retina [nTPM]":"14.9","Tissue RNA - salivary gland [nTPM]":"25.3","Tissue RNA - seminal vesicle [nTPM]":"29.3","Tissue RNA - skeletal muscle [nTPM]":"7.7","Tissue RNA - skin 1 [nTPM]":"15.8","Tissue RNA - small intestine [nTPM]":"31.0","Tissue RNA - smooth muscle [nTPM]":"30.6","Tissue RNA - spinal cord [nTPM]":"12.4","Tissue RNA - spleen [nTPM]":"24.4","Tissue RNA - stomach 1 [nTPM]":"35.5","Tissue RNA - testis [nTPM]":"13.5","Tissue RNA - thalamus [nTPM]":"13.5","Tissue RNA - thymus [nTPM]":"17.5","Tissue RNA - thyroid gland [nTPM]":"52.8","Tissue RNA - tongue [nTPM]":"10.8","Tissue RNA - tonsil [nTPM]":"23.0","Tissue RNA - urinary bladder [nTPM]":"31.8","Tissue RNA - vagina [nTPM]":"16.2","Tissue RNA - white matter [nTPM]":"15.1","Cell RNA - A-431 [nTPM]":"37.4","Cell RNA - A549 [nTPM]":"63.6","Cell RNA - AF22 [nTPM]":"39.8","Cell RNA - AN3-CA [nTPM]":"48.3","Cell RNA - ASC diff [nTPM]":"241.9","Cell RNA - ASC TERT1 [nTPM]":"123.7","Cell RNA - BEWO [nTPM]":"857.2","Cell RNA - BJ [nTPM]":"59.1","Cell RNA - BJ hTERT+ [nTPM]":"157.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"73.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"95.1","Cell RNA - CACO-2 [nTPM]":"91.3","Cell RNA - CAPAN-2 [nTPM]":"86.5","Cell RNA - Daudi [nTPM]":"17.9","Cell RNA - EFO-21 [nTPM]":"50.9","Cell RNA - fHDF\/TERT166 [nTPM]":"120.9","Cell RNA - GAMG [nTPM]":"53.9","Cell RNA - HaCaT [nTPM]":"35.1","Cell RNA - HAP1 [nTPM]":"38.1","Cell RNA - HBEC3-KT [nTPM]":"75.5","Cell RNA - HBF TERT88 [nTPM]":"53.7","Cell RNA - HDLM-2 [nTPM]":"104.9","Cell RNA - HEK 293 [nTPM]":"33.0","Cell RNA - HEL [nTPM]":"69.9","Cell RNA - HeLa [nTPM]":"35.3","Cell RNA - Hep G2 [nTPM]":"47.4","Cell RNA - HHSteC [nTPM]":"124.3","Cell RNA - HL-60 [nTPM]":"50.5","Cell RNA - HMC-1 [nTPM]":"69.9","Cell RNA - HSkMC [nTPM]":"144.9","Cell RNA - hTCEpi [nTPM]":"70.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"67.0","Cell RNA - hTERT-HME1 [nTPM]":"39.2","Cell RNA - hTERT-RPE1 [nTPM]":"144.1","Cell RNA - HUVEC TERT2 [nTPM]":"116.5","Cell RNA - JURKAT [nTPM]":"24.7","Cell RNA - K-562 [nTPM]":"64.3","Cell RNA - Karpas-707 [nTPM]":"67.0","Cell RNA - LHCN-M2 [nTPM]":"81.8","Cell RNA - MCF7 [nTPM]":"44.6","Cell RNA - MOLT-4 [nTPM]":"29.6","Cell RNA - NB-4 [nTPM]":"31.6","Cell RNA - NTERA-2 [nTPM]":"26.4","Cell RNA - OE19 [nTPM]":"78.0","Cell RNA - PC-3 [nTPM]":"27.0","Cell RNA - REH [nTPM]":"24.7","Cell RNA - RH-30 [nTPM]":"26.4","Cell RNA - RPMI-8226 [nTPM]":"86.6","Cell RNA - RPTEC TERT1 [nTPM]":"78.4","Cell RNA - RT4 [nTPM]":"54.4","Cell RNA - SCLC-21H [nTPM]":"12.0","Cell RNA - SH-SY5Y [nTPM]":"40.3","Cell RNA - SiHa [nTPM]":"75.0","Cell RNA - SK-BR-3 [nTPM]":"120.2","Cell RNA - SK-MEL-30 [nTPM]":"74.4","Cell RNA - SuSa [nTPM]":"69.3","Cell RNA - T-47d [nTPM]":"80.3","Cell RNA - THP-1 [nTPM]":"130.2","Cell RNA - TIME [nTPM]":"67.7","Cell RNA - U-138 MG [nTPM]":"46.8","Cell RNA - U-2 OS [nTPM]":"32.2","Cell RNA - U-2197 [nTPM]":"65.2","Cell RNA - U-251 MG [nTPM]":"50.1","Cell RNA - U-266\/70 [nTPM]":"53.2","Cell RNA - U-266\/84 [nTPM]":"87.9","Cell RNA - U-698 [nTPM]":"5.9","Cell RNA - U-87 MG [nTPM]":"99.6","Cell RNA - U-937 [nTPM]":"71.2","Cell RNA - WM-115 [nTPM]":"36.7","Blood RNA - basophil [nTPM]":"43.9","Blood RNA - classical monocyte [nTPM]":"146.2","Blood RNA - eosinophil [nTPM]":"86.4","Blood RNA - gdT-cell [nTPM]":"29.2","Blood RNA - intermediate monocyte [nTPM]":"125.8","Blood RNA - MAIT T-cell [nTPM]":"40.4","Blood RNA - memory B-cell [nTPM]":"37.9","Blood RNA - memory CD4 T-cell [nTPM]":"34.3","Blood RNA - memory CD8 T-cell [nTPM]":"31.8","Blood RNA - myeloid DC [nTPM]":"166.5","Blood RNA - naive B-cell [nTPM]":"35.6","Blood RNA - naive CD4 T-cell [nTPM]":"17.9","Blood RNA - naive CD8 T-cell [nTPM]":"21.8","Blood RNA - neutrophil [nTPM]":"56.6","Blood RNA - NK-cell [nTPM]":"26.0","Blood RNA - non-classical monocyte [nTPM]":"92.1","Blood RNA - plasmacytoid DC [nTPM]":"35.1","Blood RNA - T-reg [nTPM]":"77.1","Blood RNA - total PBMC [nTPM]":"91.9","Brain RNA - amygdala [nTPM]":"12.1","Brain RNA - basal ganglia [nTPM]":"13.0","Brain RNA - cerebellum [nTPM]":"12.5","Brain RNA - cerebral cortex [nTPM]":"14.8","Brain RNA - hippocampal formation [nTPM]":"12.5","Brain RNA - hypothalamus [nTPM]":"14.8","Brain RNA - medulla oblongata [nTPM]":"14.3","Brain RNA - midbrain [nTPM]":"12.9","Brain RNA - pons [nTPM]":"15.4","Brain RNA - spinal cord [nTPM]":"12.4","Brain RNA - thalamus [nTPM]":"13.5","Brain RNA - white matter [nTPM]":"15.1","Single Cell Type RNA - Adipocytes [nTPM]":"8.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.3","Single Cell Type RNA - Astrocytes [nTPM]":"39.2","Single Cell Type RNA - B-cells [nTPM]":"18.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"60.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"11.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"34.3","Single Cell Type RNA - Club cells [nTPM]":"43.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"100.1","Single Cell Type RNA - dendritic cells [nTPM]":"14.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"41.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"27.4","Single Cell Type RNA - Ductal cells [nTPM]":"53.5","Single Cell Type RNA - Early spermatids [nTPM]":"24.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.0","Single Cell Type RNA - Endothelial cells [nTPM]":"17.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.9","Single Cell Type RNA - Erythroid cells [nTPM]":"20.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"46.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"35.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"55.3","Single Cell Type RNA - Fibroblasts [nTPM]":"29.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"26.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"27.1","Single Cell Type RNA - granulocytes [nTPM]":"26.6","Single Cell Type RNA - Granulosa cells [nTPM]":"20.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.6","Single Cell Type RNA - Hepatocytes [nTPM]":"39.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"79.5","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"46.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.5","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"43.9","Single Cell Type RNA - Langerhans cells [nTPM]":"13.9","Single Cell Type RNA - Late spermatids [nTPM]":"5.0","Single Cell Type RNA - Leydig cells [nTPM]":"15.2","Single Cell Type RNA - Macrophages [nTPM]":"41.7","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"64.6","Single Cell Type RNA - Muller glia cells [nTPM]":"16.5","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"27.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"24.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"28.1","Single Cell Type RNA - Paneth cells [nTPM]":"43.4","Single Cell Type RNA - Peritubular cells [nTPM]":"21.1","Single Cell Type RNA - Plasma cells [nTPM]":"19.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"36.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"33.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"31.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"6.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"49.1","Single Cell Type RNA - T-cells [nTPM]":"18.7","Single Cell Type RNA - Theca cells [nTPM]":"51.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"32.0","Single Cell Type RNA - Urothelial cells [nTPM]":"12.1"},{"Gene":"GLDC","Gene synonym":["GCSP","NKH"],"Ensembl":"ENSG00000178445","Gene description":"Glycine decarboxylase","Uniprot":["P23378"],"Chromosome":"9","Position":"6532467-6645729","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"liver":"173.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"31.3","Cytotrophoblasts":"79.0","Extravillous trophoblasts":"41.6","Hepatocytes":"120.5","Oligodendrocyte precursor cells":"52.3","Proximal tubular cells":"31.6","Syncytiotrophoblasts":"46.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"41.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"235.7","CACO-2":"58.2","HMC-1":"45.6","RPTEC TERT1":"95.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002318","HPA052887"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"740000","Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA002318":"AB_1849700","HPA052887":"AB_2681980"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.24e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.50e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"15.3","Tissue RNA - appendix [nTPM]":"1.4","Tissue RNA - basal ganglia [nTPM]":"15.5","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"0.8","Tissue RNA - cerebellum [nTPM]":"14.7","Tissue RNA - cerebral cortex [nTPM]":"23.7","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"12.9","Tissue RNA - colon [nTPM]":"1.0","Tissue RNA - duodenum [nTPM]":"0.8","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"5.2","Tissue RNA - esophagus [nTPM]":"3.2","Tissue RNA - fallopian tube [nTPM]":"0.7","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"14.8","Tissue RNA - hypothalamus [nTPM]":"14.4","Tissue RNA - kidney [nTPM]":"38.2","Tissue RNA - liver [nTPM]":"173.5","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"1.6","Tissue RNA - medulla oblongata [nTPM]":"14.0","Tissue RNA - midbrain [nTPM]":"13.6","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"4.9","Tissue RNA - placenta [nTPM]":"15.2","Tissue RNA - pons [nTPM]":"13.4","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"1.6","Tissue RNA - salivary gland [nTPM]":"1.1","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"1.3","Tissue RNA - skin 1 [nTPM]":"4.5","Tissue RNA - small intestine [nTPM]":"0.8","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"13.1","Tissue RNA - spleen [nTPM]":"1.2","Tissue RNA - stomach 1 [nTPM]":"1.0","Tissue RNA - testis [nTPM]":"3.5","Tissue RNA - thalamus [nTPM]":"15.8","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"5.1","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"1.2","Tissue RNA - urinary bladder [nTPM]":"1.1","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"15.3","Cell RNA - A-431 [nTPM]":"0.6","Cell RNA - A549 [nTPM]":"4.9","Cell RNA - AF22 [nTPM]":"2.1","Cell RNA - AN3-CA [nTPM]":"25.6","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"235.7","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"58.2","Cell RNA - CAPAN-2 [nTPM]":"0.5","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"5.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.7","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.7","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"1.2","Cell RNA - HEK 293 [nTPM]":"13.4","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"38.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"45.6","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.8","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"1.0","Cell RNA - HUVEC TERT2 [nTPM]":"9.0","Cell RNA - JURKAT [nTPM]":"4.3","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"1.2","Cell RNA - MCF7 [nTPM]":"1.5","Cell RNA - MOLT-4 [nTPM]":"0.9","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"27.5","Cell RNA - OE19 [nTPM]":"4.6","Cell RNA - PC-3 [nTPM]":"3.8","Cell RNA - REH [nTPM]":"1.3","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"95.4","Cell RNA - RT4 [nTPM]":"1.0","Cell RNA - SCLC-21H [nTPM]":"22.6","Cell RNA - SH-SY5Y [nTPM]":"11.7","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"21.4","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"13.9","Cell RNA - T-47d [nTPM]":"5.3","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"3.0","Cell RNA - U-138 MG [nTPM]":"0.6","Cell RNA - U-2 OS [nTPM]":"0.6","Cell RNA - U-2197 [nTPM]":"2.6","Cell RNA - U-251 MG [nTPM]":"1.3","Cell RNA - U-266\/70 [nTPM]":"1.1","Cell RNA - U-266\/84 [nTPM]":"34.4","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.8","Cell RNA - U-937 [nTPM]":"2.4","Cell RNA - WM-115 [nTPM]":"5.1","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"15.3","Brain RNA - basal ganglia [nTPM]":"15.5","Brain RNA - cerebellum [nTPM]":"14.7","Brain RNA - cerebral cortex [nTPM]":"23.7","Brain RNA - hippocampal formation [nTPM]":"14.8","Brain RNA - hypothalamus [nTPM]":"14.4","Brain RNA - medulla oblongata [nTPM]":"14.0","Brain RNA - midbrain [nTPM]":"13.6","Brain RNA - pons [nTPM]":"13.4","Brain RNA - spinal cord [nTPM]":"13.1","Brain RNA - thalamus [nTPM]":"15.8","Brain RNA - white matter [nTPM]":"15.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"17.6","Single Cell Type RNA - B-cells [nTPM]":"1.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"79.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"12.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"21.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"41.6","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"120.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"10.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"9.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"52.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"15.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"31.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.8","Single Cell Type RNA - Spermatocytes [nTPM]":"4.5","Single Cell Type RNA - Spermatogonia [nTPM]":"5.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"46.0","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"GLE1","Gene synonym":["GLE1L","hGLE1","LCCS1"],"Ensembl":"ENSG00000119392","Gene description":"GLE1 RNA export mediator","Uniprot":["Q53GS7"],"Chromosome":"9","Position":"128504719-128542288","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"77.0","Late spermatids":"58.1","Spermatocytes":"51.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041689","HPA043538","HPA061560"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear membrane","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA041689":"AB_2677617","HPA043538":"AB_2678539","HPA061560":"AB_2684560"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.49e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.04e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.6","Tissue RNA - adrenal gland [nTPM]":"14.0","Tissue RNA - amygdala [nTPM]":"9.2","Tissue RNA - appendix [nTPM]":"15.7","Tissue RNA - basal ganglia [nTPM]":"9.2","Tissue RNA - bone marrow [nTPM]":"15.1","Tissue RNA - breast [nTPM]":"15.7","Tissue RNA - cerebellum [nTPM]":"12.4","Tissue RNA - cerebral cortex [nTPM]":"11.3","Tissue RNA - cervix [nTPM]":"13.0","Tissue RNA - choroid plexus [nTPM]":"13.4","Tissue RNA - colon [nTPM]":"17.4","Tissue RNA - duodenum [nTPM]":"16.2","Tissue RNA - endometrium 1 [nTPM]":"11.6","Tissue RNA - epididymis [nTPM]":"10.8","Tissue RNA - esophagus [nTPM]":"16.4","Tissue RNA - fallopian tube [nTPM]":"14.1","Tissue RNA - gallbladder [nTPM]":"7.8","Tissue RNA - heart muscle [nTPM]":"14.9","Tissue RNA - hippocampal formation [nTPM]":"8.9","Tissue RNA - hypothalamus [nTPM]":"8.8","Tissue RNA - kidney [nTPM]":"14.1","Tissue RNA - liver [nTPM]":"16.3","Tissue RNA - lung [nTPM]":"12.3","Tissue RNA - lymph node [nTPM]":"20.4","Tissue RNA - medulla oblongata [nTPM]":"8.7","Tissue RNA - midbrain [nTPM]":"9.2","Tissue RNA - ovary [nTPM]":"16.2","Tissue RNA - pancreas [nTPM]":"9.5","Tissue RNA - parathyroid gland [nTPM]":"17.6","Tissue RNA - pituitary gland [nTPM]":"14.1","Tissue RNA - placenta [nTPM]":"9.2","Tissue RNA - pons [nTPM]":"8.6","Tissue RNA - prostate [nTPM]":"11.8","Tissue RNA - rectum [nTPM]":"18.3","Tissue RNA - retina [nTPM]":"16.5","Tissue RNA - salivary gland [nTPM]":"11.1","Tissue RNA - seminal vesicle [nTPM]":"12.4","Tissue RNA - skeletal muscle [nTPM]":"22.5","Tissue RNA - skin 1 [nTPM]":"19.1","Tissue RNA - small intestine [nTPM]":"15.8","Tissue RNA - smooth muscle [nTPM]":"12.9","Tissue RNA - spinal cord [nTPM]":"8.4","Tissue RNA - spleen [nTPM]":"15.2","Tissue RNA - stomach 1 [nTPM]":"12.9","Tissue RNA - testis [nTPM]":"32.0","Tissue RNA - thalamus [nTPM]":"9.3","Tissue RNA - thymus [nTPM]":"25.9","Tissue RNA - thyroid gland [nTPM]":"13.3","Tissue RNA - tongue [nTPM]":"12.4","Tissue RNA - tonsil [nTPM]":"22.2","Tissue RNA - urinary bladder [nTPM]":"12.8","Tissue RNA - vagina [nTPM]":"12.3","Tissue RNA - white matter [nTPM]":"8.9","Cell RNA - A-431 [nTPM]":"29.6","Cell RNA - A549 [nTPM]":"54.5","Cell RNA - AF22 [nTPM]":"26.2","Cell RNA - AN3-CA [nTPM]":"44.9","Cell RNA - ASC diff [nTPM]":"25.3","Cell RNA - ASC TERT1 [nTPM]":"25.5","Cell RNA - BEWO [nTPM]":"34.6","Cell RNA - BJ [nTPM]":"29.2","Cell RNA - BJ hTERT+ [nTPM]":"24.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"40.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"28.4","Cell RNA - CACO-2 [nTPM]":"36.8","Cell RNA - CAPAN-2 [nTPM]":"20.1","Cell RNA - Daudi [nTPM]":"59.6","Cell RNA - EFO-21 [nTPM]":"23.0","Cell RNA - fHDF\/TERT166 [nTPM]":"33.0","Cell RNA - GAMG [nTPM]":"38.6","Cell RNA - HaCaT [nTPM]":"101.4","Cell RNA - HAP1 [nTPM]":"45.9","Cell RNA - HBEC3-KT [nTPM]":"41.7","Cell RNA - HBF TERT88 [nTPM]":"34.5","Cell RNA - HDLM-2 [nTPM]":"56.9","Cell RNA - HEK 293 [nTPM]":"29.8","Cell RNA - HEL [nTPM]":"30.6","Cell RNA - HeLa [nTPM]":"57.8","Cell RNA - Hep G2 [nTPM]":"34.6","Cell RNA - HHSteC [nTPM]":"28.5","Cell RNA - HL-60 [nTPM]":"49.9","Cell RNA - HMC-1 [nTPM]":"38.8","Cell RNA - HSkMC [nTPM]":"18.1","Cell RNA - hTCEpi [nTPM]":"39.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"45.6","Cell RNA - hTERT-HME1 [nTPM]":"48.5","Cell RNA - hTERT-RPE1 [nTPM]":"22.3","Cell RNA - HUVEC TERT2 [nTPM]":"22.9","Cell RNA - JURKAT [nTPM]":"54.7","Cell RNA - K-562 [nTPM]":"44.7","Cell RNA - Karpas-707 [nTPM]":"51.0","Cell RNA - LHCN-M2 [nTPM]":"46.7","Cell RNA - MCF7 [nTPM]":"68.6","Cell RNA - MOLT-4 [nTPM]":"49.5","Cell RNA - NB-4 [nTPM]":"35.2","Cell RNA - NTERA-2 [nTPM]":"22.2","Cell RNA - OE19 [nTPM]":"79.1","Cell RNA - PC-3 [nTPM]":"46.7","Cell RNA - REH [nTPM]":"49.8","Cell RNA - RH-30 [nTPM]":"64.2","Cell RNA - RPMI-8226 [nTPM]":"79.0","Cell RNA - RPTEC TERT1 [nTPM]":"27.3","Cell RNA - RT4 [nTPM]":"26.1","Cell RNA - SCLC-21H [nTPM]":"30.9","Cell RNA - SH-SY5Y [nTPM]":"23.1","Cell RNA - SiHa [nTPM]":"71.3","Cell RNA - SK-BR-3 [nTPM]":"42.7","Cell RNA - SK-MEL-30 [nTPM]":"25.9","Cell RNA - SuSa [nTPM]":"21.1","Cell RNA - T-47d [nTPM]":"78.9","Cell RNA - THP-1 [nTPM]":"34.9","Cell RNA - TIME [nTPM]":"17.0","Cell RNA - U-138 MG [nTPM]":"42.5","Cell RNA - U-2 OS [nTPM]":"28.1","Cell RNA - U-2197 [nTPM]":"50.2","Cell RNA - U-251 MG [nTPM]":"41.2","Cell RNA - U-266\/70 [nTPM]":"50.9","Cell RNA - U-266\/84 [nTPM]":"131.9","Cell RNA - U-698 [nTPM]":"45.9","Cell RNA - U-87 MG [nTPM]":"39.9","Cell RNA - U-937 [nTPM]":"37.5","Cell RNA - WM-115 [nTPM]":"46.8","Blood RNA - basophil [nTPM]":"40.0","Blood RNA - classical monocyte [nTPM]":"21.1","Blood RNA - eosinophil [nTPM]":"24.4","Blood RNA - gdT-cell [nTPM]":"22.1","Blood RNA - intermediate monocyte [nTPM]":"26.0","Blood RNA - MAIT T-cell [nTPM]":"18.1","Blood RNA - memory B-cell [nTPM]":"13.4","Blood RNA - memory CD4 T-cell [nTPM]":"17.2","Blood RNA - memory CD8 T-cell [nTPM]":"20.0","Blood RNA - myeloid DC [nTPM]":"22.1","Blood RNA - naive B-cell [nTPM]":"20.5","Blood RNA - naive CD4 T-cell [nTPM]":"15.2","Blood RNA - naive CD8 T-cell [nTPM]":"17.7","Blood RNA - neutrophil [nTPM]":"18.0","Blood RNA - NK-cell [nTPM]":"27.4","Blood RNA - non-classical monocyte [nTPM]":"27.5","Blood RNA - plasmacytoid DC [nTPM]":"13.0","Blood RNA - T-reg [nTPM]":"22.3","Blood RNA - total PBMC [nTPM]":"19.8","Brain RNA - amygdala [nTPM]":"9.2","Brain RNA - basal ganglia [nTPM]":"9.2","Brain RNA - cerebellum [nTPM]":"12.4","Brain RNA - cerebral cortex [nTPM]":"11.3","Brain RNA - hippocampal formation [nTPM]":"8.9","Brain RNA - hypothalamus [nTPM]":"8.8","Brain RNA - medulla oblongata [nTPM]":"8.7","Brain RNA - midbrain [nTPM]":"9.2","Brain RNA - pons [nTPM]":"8.6","Brain RNA - spinal cord [nTPM]":"8.4","Brain RNA - thalamus [nTPM]":"9.3","Brain RNA - white matter [nTPM]":"8.9","Single Cell Type RNA - Adipocytes [nTPM]":"4.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.0","Single Cell Type RNA - Astrocytes [nTPM]":"11.1","Single Cell Type RNA - B-cells [nTPM]":"11.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"7.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"7.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.1","Single Cell Type RNA - dendritic cells [nTPM]":"6.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.7","Single Cell Type RNA - Early spermatids [nTPM]":"77.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.4","Single Cell Type RNA - Endothelial cells [nTPM]":"3.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"12.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.7","Single Cell Type RNA - Fibroblasts [nTPM]":"7.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.4","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"10.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.6","Single Cell Type RNA - Hepatocytes [nTPM]":"14.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.7","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.7","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"15.1","Single Cell Type RNA - Langerhans cells [nTPM]":"5.7","Single Cell Type RNA - Late spermatids [nTPM]":"58.1","Single Cell Type RNA - Leydig cells [nTPM]":"10.2","Single Cell Type RNA - Macrophages [nTPM]":"13.5","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"20.0","Single Cell Type RNA - Muller glia cells [nTPM]":"8.9","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.3","Single Cell Type RNA - Paneth cells [nTPM]":"8.0","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"13.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"16.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.3","Single Cell Type RNA - Spermatocytes [nTPM]":"51.3","Single Cell Type RNA - Spermatogonia [nTPM]":"25.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"13.3","Single Cell Type RNA - T-cells [nTPM]":"12.1","Single Cell Type RNA - Theca cells [nTPM]":"7.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.1","Single Cell Type RNA - Urothelial cells [nTPM]":"5.4"},{"Gene":"GLRB","Gene synonym":[],"Ensembl":"ENSG00000109738","Gene description":"Glycine receptor beta","Uniprot":["P48167"],"Chromosome":"4","Position":"157076125-157172090","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"35.5","parathyroid gland":"33.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"168.6","Inhibitory neurons":"110.7","Oligodendrocyte precursor cells":"110.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AN3-CA":"28.6","hTERT-RPE1":"37.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052363"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052363":"AB_2681800"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.89e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.7","Tissue RNA - adrenal gland [nTPM]":"7.0","Tissue RNA - amygdala [nTPM]":"16.5","Tissue RNA - appendix [nTPM]":"1.1","Tissue RNA - basal ganglia [nTPM]":"17.7","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"10.6","Tissue RNA - cerebellum [nTPM]":"7.4","Tissue RNA - cerebral cortex [nTPM]":"35.5","Tissue RNA - cervix [nTPM]":"9.0","Tissue RNA - choroid plexus [nTPM]":"4.5","Tissue RNA - colon [nTPM]":"3.3","Tissue RNA - duodenum [nTPM]":"0.6","Tissue RNA - endometrium 1 [nTPM]":"2.9","Tissue RNA - epididymis [nTPM]":"5.2","Tissue RNA - esophagus [nTPM]":"1.0","Tissue RNA - fallopian tube [nTPM]":"7.3","Tissue RNA - gallbladder [nTPM]":"3.2","Tissue RNA - heart muscle [nTPM]":"11.1","Tissue RNA - hippocampal formation [nTPM]":"18.0","Tissue RNA - hypothalamus [nTPM]":"12.9","Tissue RNA - kidney [nTPM]":"3.8","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"3.1","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"9.4","Tissue RNA - midbrain [nTPM]":"6.9","Tissue RNA - ovary [nTPM]":"1.2","Tissue RNA - pancreas [nTPM]":"15.2","Tissue RNA - parathyroid gland [nTPM]":"33.0","Tissue RNA - pituitary gland [nTPM]":"7.5","Tissue RNA - placenta [nTPM]":"2.6","Tissue RNA - pons [nTPM]":"10.8","Tissue RNA - prostate [nTPM]":"6.2","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"8.5","Tissue RNA - salivary gland [nTPM]":"19.5","Tissue RNA - seminal vesicle [nTPM]":"4.7","Tissue RNA - skeletal muscle [nTPM]":"3.3","Tissue RNA - skin 1 [nTPM]":"1.8","Tissue RNA - small intestine [nTPM]":"1.4","Tissue RNA - smooth muscle [nTPM]":"3.7","Tissue RNA - spinal cord [nTPM]":"5.7","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"2.9","Tissue RNA - testis [nTPM]":"1.6","Tissue RNA - thalamus [nTPM]":"9.8","Tissue RNA - thymus [nTPM]":"1.1","Tissue RNA - thyroid gland [nTPM]":"1.0","Tissue RNA - tongue [nTPM]":"4.9","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"1.4","Tissue RNA - vagina [nTPM]":"1.5","Tissue RNA - white matter [nTPM]":"13.5","Cell RNA - A-431 [nTPM]":"8.0","Cell RNA - A549 [nTPM]":"3.4","Cell RNA - AF22 [nTPM]":"9.5","Cell RNA - AN3-CA [nTPM]":"28.6","Cell RNA - ASC diff [nTPM]":"18.0","Cell RNA - ASC TERT1 [nTPM]":"7.2","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"16.0","Cell RNA - BJ hTERT+ [nTPM]":"10.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.4","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"24.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"3.7","Cell RNA - fHDF\/TERT166 [nTPM]":"16.2","Cell RNA - GAMG [nTPM]":"9.4","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"7.2","Cell RNA - HBEC3-KT [nTPM]":"2.5","Cell RNA - HBF TERT88 [nTPM]":"14.3","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"9.7","Cell RNA - HEL [nTPM]":"5.0","Cell RNA - HeLa [nTPM]":"3.8","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"8.1","Cell RNA - HL-60 [nTPM]":"6.2","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"6.4","Cell RNA - hTCEpi [nTPM]":"2.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.4","Cell RNA - hTERT-HME1 [nTPM]":"1.9","Cell RNA - hTERT-RPE1 [nTPM]":"37.8","Cell RNA - HUVEC TERT2 [nTPM]":"6.9","Cell RNA - JURKAT [nTPM]":"5.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"14.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.8","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"2.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"13.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"20.6","Cell RNA - RT4 [nTPM]":"1.5","Cell RNA - SCLC-21H [nTPM]":"10.3","Cell RNA - SH-SY5Y [nTPM]":"6.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"7.3","Cell RNA - SK-MEL-30 [nTPM]":"1.2","Cell RNA - SuSa [nTPM]":"1.4","Cell RNA - T-47d [nTPM]":"6.8","Cell RNA - THP-1 [nTPM]":"1.6","Cell RNA - TIME [nTPM]":"10.5","Cell RNA - U-138 MG [nTPM]":"4.5","Cell RNA - U-2 OS [nTPM]":"13.2","Cell RNA - U-2197 [nTPM]":"7.6","Cell RNA - U-251 MG [nTPM]":"15.3","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"10.7","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"4.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"16.5","Brain RNA - basal ganglia [nTPM]":"17.7","Brain RNA - cerebellum [nTPM]":"7.4","Brain RNA - cerebral cortex [nTPM]":"35.5","Brain RNA - hippocampal formation [nTPM]":"18.0","Brain RNA - hypothalamus [nTPM]":"12.9","Brain RNA - medulla oblongata [nTPM]":"9.4","Brain RNA - midbrain [nTPM]":"6.9","Brain RNA - pons [nTPM]":"10.8","Brain RNA - spinal cord [nTPM]":"5.7","Brain RNA - thalamus [nTPM]":"9.8","Brain RNA - white matter [nTPM]":"13.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"26.1","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"10.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"3.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"8.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.4","Single Cell Type RNA - Endothelial cells [nTPM]":"2.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"168.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"3.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"7.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"110.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1.9","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"13.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"110.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"31.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"3.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.2","Single Cell Type RNA - Spermatocytes [nTPM]":"1.3","Single Cell Type RNA - Spermatogonia [nTPM]":"3.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"1.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"GLS","Gene synonym":["GLS1","KIAA0838"],"Ensembl":"ENSG00000115419","Gene description":"Glutaminase","Uniprot":["O94925"],"Chromosome":"2","Position":"190880821-190965552","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Cataract","Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"316.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"391.8","Excitatory neurons":"427.1","Proximal tubular cells":"539.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"907.3","RPTEC TERT1":"419.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036223"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":"Intracellular and membrane","CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"92000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA036223":"AB_10669984"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.45e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-1"},"Tissue RNA - adipose tissue [nTPM]":"37.0","Tissue RNA - adrenal gland [nTPM]":"77.4","Tissue RNA - amygdala [nTPM]":"38.5","Tissue RNA - appendix [nTPM]":"45.7","Tissue RNA - basal ganglia [nTPM]":"50.5","Tissue RNA - bone marrow [nTPM]":"28.7","Tissue RNA - breast [nTPM]":"32.0","Tissue RNA - cerebellum [nTPM]":"40.5","Tissue RNA - cerebral cortex [nTPM]":"74.6","Tissue RNA - cervix [nTPM]":"31.0","Tissue RNA - choroid plexus [nTPM]":"35.6","Tissue RNA - colon [nTPM]":"32.0","Tissue RNA - duodenum [nTPM]":"92.2","Tissue RNA - endometrium 1 [nTPM]":"28.8","Tissue RNA - epididymis [nTPM]":"26.6","Tissue RNA - esophagus [nTPM]":"16.8","Tissue RNA - fallopian tube [nTPM]":"25.1","Tissue RNA - gallbladder [nTPM]":"41.8","Tissue RNA - heart muscle [nTPM]":"34.7","Tissue RNA - hippocampal formation [nTPM]":"55.5","Tissue RNA - hypothalamus [nTPM]":"35.9","Tissue RNA - kidney [nTPM]":"316.8","Tissue RNA - liver [nTPM]":"11.7","Tissue RNA - lung [nTPM]":"55.6","Tissue RNA - lymph node [nTPM]":"68.0","Tissue RNA - medulla oblongata [nTPM]":"44.7","Tissue RNA - midbrain [nTPM]":"19.8","Tissue RNA - ovary [nTPM]":"28.9","Tissue RNA - pancreas [nTPM]":"36.9","Tissue RNA - parathyroid gland [nTPM]":"62.0","Tissue RNA - pituitary gland [nTPM]":"19.9","Tissue RNA - placenta [nTPM]":"35.8","Tissue RNA - pons [nTPM]":"52.5","Tissue RNA - prostate [nTPM]":"20.8","Tissue RNA - rectum [nTPM]":"30.1","Tissue RNA - retina [nTPM]":"81.8","Tissue RNA - salivary gland [nTPM]":"20.4","Tissue RNA - seminal vesicle [nTPM]":"31.2","Tissue RNA - skeletal muscle [nTPM]":"15.8","Tissue RNA - skin 1 [nTPM]":"28.5","Tissue RNA - small intestine [nTPM]":"103.4","Tissue RNA - smooth muscle [nTPM]":"36.9","Tissue RNA - spinal cord [nTPM]":"12.0","Tissue RNA - spleen [nTPM]":"49.3","Tissue RNA - stomach 1 [nTPM]":"18.7","Tissue RNA - testis [nTPM]":"16.2","Tissue RNA - thalamus [nTPM]":"24.1","Tissue RNA - thymus [nTPM]":"41.7","Tissue RNA - thyroid gland [nTPM]":"35.7","Tissue RNA - tongue [nTPM]":"23.6","Tissue RNA - tonsil [nTPM]":"57.9","Tissue RNA - urinary bladder [nTPM]":"36.5","Tissue RNA - vagina [nTPM]":"23.6","Tissue RNA - white matter [nTPM]":"44.8","Cell RNA - A-431 [nTPM]":"43.6","Cell RNA - A549 [nTPM]":"47.2","Cell RNA - AF22 [nTPM]":"32.4","Cell RNA - AN3-CA [nTPM]":"43.1","Cell RNA - ASC diff [nTPM]":"99.7","Cell RNA - ASC TERT1 [nTPM]":"68.9","Cell RNA - BEWO [nTPM]":"84.0","Cell RNA - BJ [nTPM]":"126.8","Cell RNA - BJ hTERT+ [nTPM]":"95.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"90.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"103.1","Cell RNA - CACO-2 [nTPM]":"58.1","Cell RNA - CAPAN-2 [nTPM]":"42.1","Cell RNA - Daudi [nTPM]":"88.5","Cell RNA - EFO-21 [nTPM]":"907.3","Cell RNA - fHDF\/TERT166 [nTPM]":"269.3","Cell RNA - GAMG [nTPM]":"46.1","Cell RNA - HaCaT [nTPM]":"55.6","Cell RNA - HAP1 [nTPM]":"58.0","Cell RNA - HBEC3-KT [nTPM]":"50.0","Cell RNA - HBF TERT88 [nTPM]":"131.5","Cell RNA - HDLM-2 [nTPM]":"219.8","Cell RNA - HEK 293 [nTPM]":"37.7","Cell RNA - HEL [nTPM]":"147.3","Cell RNA - HeLa [nTPM]":"69.1","Cell RNA - Hep G2 [nTPM]":"72.2","Cell RNA - HHSteC [nTPM]":"90.8","Cell RNA - HL-60 [nTPM]":"87.2","Cell RNA - HMC-1 [nTPM]":"66.5","Cell RNA - HSkMC [nTPM]":"62.9","Cell RNA - hTCEpi [nTPM]":"51.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"71.2","Cell RNA - hTERT-HME1 [nTPM]":"48.4","Cell RNA - hTERT-RPE1 [nTPM]":"90.1","Cell RNA - HUVEC TERT2 [nTPM]":"119.3","Cell RNA - JURKAT [nTPM]":"36.7","Cell RNA - K-562 [nTPM]":"69.3","Cell RNA - Karpas-707 [nTPM]":"175.2","Cell RNA - LHCN-M2 [nTPM]":"203.3","Cell RNA - MCF7 [nTPM]":"22.8","Cell RNA - MOLT-4 [nTPM]":"59.2","Cell RNA - NB-4 [nTPM]":"83.7","Cell RNA - NTERA-2 [nTPM]":"86.9","Cell RNA - OE19 [nTPM]":"25.7","Cell RNA - PC-3 [nTPM]":"76.7","Cell RNA - REH [nTPM]":"74.2","Cell RNA - RH-30 [nTPM]":"83.7","Cell RNA - RPMI-8226 [nTPM]":"77.4","Cell RNA - RPTEC TERT1 [nTPM]":"419.2","Cell RNA - RT4 [nTPM]":"78.9","Cell RNA - SCLC-21H [nTPM]":"44.9","Cell RNA - SH-SY5Y [nTPM]":"46.8","Cell RNA - SiHa [nTPM]":"172.8","Cell RNA - SK-BR-3 [nTPM]":"37.9","Cell RNA - SK-MEL-30 [nTPM]":"169.2","Cell RNA - SuSa [nTPM]":"115.1","Cell RNA - T-47d [nTPM]":"14.9","Cell RNA - THP-1 [nTPM]":"53.0","Cell RNA - TIME [nTPM]":"85.3","Cell RNA - U-138 MG [nTPM]":"129.4","Cell RNA - U-2 OS [nTPM]":"94.5","Cell RNA - U-2197 [nTPM]":"65.9","Cell RNA - U-251 MG [nTPM]":"156.8","Cell RNA - U-266\/70 [nTPM]":"56.2","Cell RNA - U-266\/84 [nTPM]":"138.9","Cell RNA - U-698 [nTPM]":"122.1","Cell RNA - U-87 MG [nTPM]":"46.7","Cell RNA - U-937 [nTPM]":"70.6","Cell RNA - WM-115 [nTPM]":"105.5","Blood RNA - basophil [nTPM]":"6.4","Blood RNA - classical monocyte [nTPM]":"1.0","Blood RNA - eosinophil [nTPM]":"1.9","Blood RNA - gdT-cell [nTPM]":"3.7","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"6.5","Blood RNA - memory B-cell [nTPM]":"3.4","Blood RNA - memory CD4 T-cell [nTPM]":"4.4","Blood RNA - memory CD8 T-cell [nTPM]":"4.8","Blood RNA - myeloid DC [nTPM]":"1.6","Blood RNA - naive B-cell [nTPM]":"3.8","Blood RNA - naive CD4 T-cell [nTPM]":"4.5","Blood RNA - naive CD8 T-cell [nTPM]":"5.5","Blood RNA - neutrophil [nTPM]":"2.1","Blood RNA - NK-cell [nTPM]":"2.8","Blood RNA - non-classical monocyte [nTPM]":"1.1","Blood RNA - plasmacytoid DC [nTPM]":"3.6","Blood RNA - T-reg [nTPM]":"4.1","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"38.5","Brain RNA - basal ganglia [nTPM]":"50.5","Brain RNA - cerebellum [nTPM]":"40.5","Brain RNA - cerebral cortex [nTPM]":"74.6","Brain RNA - hippocampal formation [nTPM]":"55.5","Brain RNA - hypothalamus [nTPM]":"35.9","Brain RNA - medulla oblongata [nTPM]":"44.7","Brain RNA - midbrain [nTPM]":"19.8","Brain RNA - pons [nTPM]":"52.5","Brain RNA - spinal cord [nTPM]":"12.0","Brain RNA - thalamus [nTPM]":"24.1","Brain RNA - white matter [nTPM]":"44.8","Single Cell Type RNA - Adipocytes [nTPM]":"81.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"189.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"122.5","Single Cell Type RNA - Astrocytes [nTPM]":"61.0","Single Cell Type RNA - B-cells [nTPM]":"89.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"174.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"44.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"60.9","Single Cell Type RNA - Bipolar cells [nTPM]":"93.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"51.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"49.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"38.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"35.8","Single Cell Type RNA - Club cells [nTPM]":"28.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"391.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"210.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.4","Single Cell Type RNA - dendritic cells [nTPM]":"128.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"100.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"50.9","Single Cell Type RNA - Ductal cells [nTPM]":"21.4","Single Cell Type RNA - Early spermatids [nTPM]":"6.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"33.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"66.8","Single Cell Type RNA - Endothelial cells [nTPM]":"68.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"59.2","Single Cell Type RNA - Erythroid cells [nTPM]":"17.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"427.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"24.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.6","Single Cell Type RNA - Fibroblasts [nTPM]":"66.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"46.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"97.9","Single Cell Type RNA - granulocytes [nTPM]":"36.8","Single Cell Type RNA - Granulosa cells [nTPM]":"48.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"63.5","Single Cell Type RNA - Hepatocytes [nTPM]":"4.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"29.1","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"270.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"36.7","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"31.2","Single Cell Type RNA - Langerhans cells [nTPM]":"230.0","Single Cell Type RNA - Late spermatids [nTPM]":"7.3","Single Cell Type RNA - Leydig cells [nTPM]":"28.6","Single Cell Type RNA - Macrophages [nTPM]":"84.3","Single Cell Type RNA - Melanocytes [nTPM]":"88.9","Single Cell Type RNA - Microglial cells [nTPM]":"143.4","Single Cell Type RNA - monocytes [nTPM]":"68.4","Single Cell Type RNA - Muller glia cells [nTPM]":"11.9","Single Cell Type RNA - NK-cells [nTPM]":"55.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"163.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"146.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.8","Single Cell Type RNA - Paneth cells [nTPM]":"92.9","Single Cell Type RNA - Peritubular cells [nTPM]":"43.2","Single Cell Type RNA - Plasma cells [nTPM]":"118.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"70.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"165.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"539.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"111.9","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"71.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"76.0","Single Cell Type RNA - Spermatocytes [nTPM]":"11.3","Single Cell Type RNA - Spermatogonia [nTPM]":"12.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"61.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"162.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.0","Single Cell Type RNA - T-cells [nTPM]":"114.0","Single Cell Type RNA - Theca cells [nTPM]":"97.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"43.6","Single Cell Type RNA - Urothelial cells [nTPM]":"56.7"},{"Gene":"GLUD1","Gene synonym":["GDH","GLUD"],"Ensembl":"ENSG00000148672","Gene description":"Glutamate dehydrogenase 1","Uniprot":["P00367"],"Chromosome":"10","Position":"87050202-87094843","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"816.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"294.1","Hepatocytes":"402.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"555.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042492","HPA044839","HPA061369"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"23000000","Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA042492":"AB_2678024","HPA044839":"AB_2679107","HPA061369":"AB_2684494"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.81e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.76e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.44e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Tissue RNA - adipose tissue [nTPM]":"70.1","Tissue RNA - adrenal gland [nTPM]":"93.0","Tissue RNA - amygdala [nTPM]":"217.2","Tissue RNA - appendix [nTPM]":"44.8","Tissue RNA - basal ganglia [nTPM]":"219.0","Tissue RNA - bone marrow [nTPM]":"29.2","Tissue RNA - breast [nTPM]":"96.4","Tissue RNA - cerebellum [nTPM]":"180.4","Tissue RNA - cerebral cortex [nTPM]":"216.8","Tissue RNA - cervix [nTPM]":"50.2","Tissue RNA - choroid plexus [nTPM]":"135.8","Tissue RNA - colon [nTPM]":"63.4","Tissue RNA - duodenum [nTPM]":"80.9","Tissue RNA - endometrium 1 [nTPM]":"48.1","Tissue RNA - epididymis [nTPM]":"30.0","Tissue RNA - esophagus [nTPM]":"77.0","Tissue RNA - fallopian tube [nTPM]":"47.4","Tissue RNA - gallbladder [nTPM]":"53.3","Tissue RNA - heart muscle [nTPM]":"75.6","Tissue RNA - hippocampal formation [nTPM]":"193.3","Tissue RNA - hypothalamus [nTPM]":"223.2","Tissue RNA - kidney [nTPM]":"249.2","Tissue RNA - liver [nTPM]":"816.4","Tissue RNA - lung [nTPM]":"57.7","Tissue RNA - lymph node [nTPM]":"42.9","Tissue RNA - medulla oblongata [nTPM]":"220.9","Tissue RNA - midbrain [nTPM]":"222.9","Tissue RNA - ovary [nTPM]":"71.6","Tissue RNA - pancreas [nTPM]":"66.2","Tissue RNA - parathyroid gland [nTPM]":"39.0","Tissue RNA - pituitary gland [nTPM]":"37.1","Tissue RNA - placenta [nTPM]":"58.8","Tissue RNA - pons [nTPM]":"202.3","Tissue RNA - prostate [nTPM]":"110.5","Tissue RNA - rectum [nTPM]":"61.5","Tissue RNA - retina [nTPM]":"90.2","Tissue RNA - salivary gland [nTPM]":"55.6","Tissue RNA - seminal vesicle [nTPM]":"53.2","Tissue RNA - skeletal muscle [nTPM]":"51.1","Tissue RNA - skin 1 [nTPM]":"84.2","Tissue RNA - small intestine [nTPM]":"88.6","Tissue RNA - smooth muscle [nTPM]":"53.3","Tissue RNA - spinal cord [nTPM]":"223.2","Tissue RNA - spleen [nTPM]":"46.4","Tissue RNA - stomach 1 [nTPM]":"57.0","Tissue RNA - testis [nTPM]":"22.3","Tissue RNA - thalamus [nTPM]":"254.6","Tissue RNA - thymus [nTPM]":"44.8","Tissue RNA - thyroid gland [nTPM]":"68.1","Tissue RNA - tongue [nTPM]":"64.4","Tissue RNA - tonsil [nTPM]":"59.2","Tissue RNA - urinary bladder [nTPM]":"68.1","Tissue RNA - vagina [nTPM]":"55.6","Tissue RNA - white matter [nTPM]":"202.3","Cell RNA - A-431 [nTPM]":"127.1","Cell RNA - A549 [nTPM]":"100.3","Cell RNA - AF22 [nTPM]":"77.1","Cell RNA - AN3-CA [nTPM]":"131.5","Cell RNA - ASC diff [nTPM]":"143.0","Cell RNA - ASC TERT1 [nTPM]":"174.5","Cell RNA - BEWO [nTPM]":"84.0","Cell RNA - BJ [nTPM]":"97.7","Cell RNA - BJ hTERT+ [nTPM]":"167.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"92.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"100.5","Cell RNA - CACO-2 [nTPM]":"233.0","Cell RNA - CAPAN-2 [nTPM]":"120.6","Cell RNA - Daudi [nTPM]":"141.5","Cell RNA - EFO-21 [nTPM]":"77.8","Cell RNA - fHDF\/TERT166 [nTPM]":"143.4","Cell RNA - GAMG [nTPM]":"53.0","Cell RNA - HaCaT [nTPM]":"194.7","Cell RNA - HAP1 [nTPM]":"101.4","Cell RNA - HBEC3-KT [nTPM]":"98.5","Cell RNA - HBF TERT88 [nTPM]":"98.0","Cell RNA - HDLM-2 [nTPM]":"102.7","Cell RNA - HEK 293 [nTPM]":"79.8","Cell RNA - HEL [nTPM]":"69.0","Cell RNA - HeLa [nTPM]":"55.9","Cell RNA - Hep G2 [nTPM]":"555.0","Cell RNA - HHSteC [nTPM]":"318.1","Cell RNA - HL-60 [nTPM]":"163.2","Cell RNA - HMC-1 [nTPM]":"95.5","Cell RNA - HSkMC [nTPM]":"121.3","Cell RNA - hTCEpi [nTPM]":"181.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"103.2","Cell RNA - hTERT-HME1 [nTPM]":"304.9","Cell RNA - hTERT-RPE1 [nTPM]":"140.3","Cell RNA - HUVEC TERT2 [nTPM]":"112.0","Cell RNA - JURKAT [nTPM]":"109.3","Cell RNA - K-562 [nTPM]":"70.7","Cell RNA - Karpas-707 [nTPM]":"124.0","Cell RNA - LHCN-M2 [nTPM]":"101.0","Cell RNA - MCF7 [nTPM]":"92.1","Cell RNA - MOLT-4 [nTPM]":"148.1","Cell RNA - NB-4 [nTPM]":"145.7","Cell RNA - NTERA-2 [nTPM]":"88.2","Cell RNA - OE19 [nTPM]":"136.9","Cell RNA - PC-3 [nTPM]":"79.8","Cell RNA - REH [nTPM]":"110.4","Cell RNA - RH-30 [nTPM]":"98.3","Cell RNA - RPMI-8226 [nTPM]":"93.1","Cell RNA - RPTEC TERT1 [nTPM]":"267.4","Cell RNA - RT4 [nTPM]":"101.8","Cell RNA - SCLC-21H [nTPM]":"39.7","Cell RNA - SH-SY5Y [nTPM]":"73.9","Cell RNA - SiHa [nTPM]":"87.8","Cell RNA - SK-BR-3 [nTPM]":"68.8","Cell RNA - SK-MEL-30 [nTPM]":"126.1","Cell RNA - SuSa [nTPM]":"73.9","Cell RNA - T-47d [nTPM]":"94.3","Cell RNA - THP-1 [nTPM]":"112.8","Cell RNA - TIME [nTPM]":"112.4","Cell RNA - U-138 MG [nTPM]":"47.8","Cell RNA - U-2 OS [nTPM]":"42.5","Cell RNA - U-2197 [nTPM]":"98.2","Cell RNA - U-251 MG [nTPM]":"101.0","Cell RNA - U-266\/70 [nTPM]":"73.6","Cell RNA - U-266\/84 [nTPM]":"81.4","Cell RNA - U-698 [nTPM]":"167.5","Cell RNA - U-87 MG [nTPM]":"115.3","Cell RNA - U-937 [nTPM]":"182.8","Cell RNA - WM-115 [nTPM]":"29.3","Blood RNA - basophil [nTPM]":"9.1","Blood RNA - classical monocyte [nTPM]":"14.2","Blood RNA - eosinophil [nTPM]":"9.7","Blood RNA - gdT-cell [nTPM]":"8.3","Blood RNA - intermediate monocyte [nTPM]":"11.1","Blood RNA - MAIT T-cell [nTPM]":"10.3","Blood RNA - memory B-cell [nTPM]":"9.8","Blood RNA - memory CD4 T-cell [nTPM]":"11.2","Blood RNA - memory CD8 T-cell [nTPM]":"10.1","Blood RNA - myeloid DC [nTPM]":"15.9","Blood RNA - naive B-cell [nTPM]":"11.3","Blood RNA - naive CD4 T-cell [nTPM]":"9.9","Blood RNA - naive CD8 T-cell [nTPM]":"8.0","Blood RNA - neutrophil [nTPM]":"1.2","Blood RNA - NK-cell [nTPM]":"13.6","Blood RNA - non-classical monocyte [nTPM]":"16.0","Blood RNA - plasmacytoid DC [nTPM]":"5.9","Blood RNA - T-reg [nTPM]":"12.6","Blood RNA - total PBMC [nTPM]":"6.5","Brain RNA - amygdala [nTPM]":"217.2","Brain RNA - basal ganglia [nTPM]":"219.0","Brain RNA - cerebellum [nTPM]":"180.4","Brain RNA - cerebral cortex [nTPM]":"216.8","Brain RNA - hippocampal formation [nTPM]":"193.3","Brain RNA - hypothalamus [nTPM]":"223.2","Brain RNA - medulla oblongata [nTPM]":"220.9","Brain RNA - midbrain [nTPM]":"222.9","Brain RNA - pons [nTPM]":"202.3","Brain RNA - spinal cord [nTPM]":"223.2","Brain RNA - thalamus [nTPM]":"254.6","Brain RNA - white matter [nTPM]":"202.3","Single Cell Type RNA - Adipocytes [nTPM]":"49.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.9","Single Cell Type RNA - Astrocytes [nTPM]":"294.1","Single Cell Type RNA - B-cells [nTPM]":"56.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"106.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"57.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"32.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"105.3","Single Cell Type RNA - Bipolar cells [nTPM]":"22.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"83.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"38.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"60.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"57.2","Single Cell Type RNA - Club cells [nTPM]":"47.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"60.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"95.7","Single Cell Type RNA - dendritic cells [nTPM]":"45.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"56.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"156.5","Single Cell Type RNA - Ductal cells [nTPM]":"32.5","Single Cell Type RNA - Early spermatids [nTPM]":"14.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"37.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"44.0","Single Cell Type RNA - Endothelial cells [nTPM]":"54.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"39.4","Single Cell Type RNA - Erythroid cells [nTPM]":"52.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"35.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"33.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"63.8","Single Cell Type RNA - Fibroblasts [nTPM]":"89.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"86.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"59.7","Single Cell Type RNA - granulocytes [nTPM]":"43.2","Single Cell Type RNA - Granulosa cells [nTPM]":"33.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"50.7","Single Cell Type RNA - Hepatocytes [nTPM]":"402.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"69.1","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"38.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"49.5","Single Cell Type RNA - Ionocytes [nTPM]":"36.7","Single Cell Type RNA - Kupffer cells [nTPM]":"74.1","Single Cell Type RNA - Langerhans cells [nTPM]":"184.5","Single Cell Type RNA - Late spermatids [nTPM]":"26.0","Single Cell Type RNA - Leydig cells [nTPM]":"88.0","Single Cell Type RNA - Macrophages [nTPM]":"81.4","Single Cell Type RNA - Melanocytes [nTPM]":"104.9","Single Cell Type RNA - Microglial cells [nTPM]":"42.2","Single Cell Type RNA - monocytes [nTPM]":"50.6","Single Cell Type RNA - Muller glia cells [nTPM]":"140.0","Single Cell Type RNA - NK-cells [nTPM]":"39.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"48.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"42.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"50.2","Single Cell Type RNA - Paneth cells [nTPM]":"38.3","Single Cell Type RNA - Peritubular cells [nTPM]":"90.7","Single Cell Type RNA - Plasma cells [nTPM]":"75.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"103.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"124.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"175.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"68.9","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"41.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"55.9","Single Cell Type RNA - Spermatocytes [nTPM]":"11.4","Single Cell Type RNA - Spermatogonia [nTPM]":"8.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"189.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"122.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"47.6","Single Cell Type RNA - T-cells [nTPM]":"84.6","Single Cell Type RNA - Theca cells [nTPM]":"70.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"49.6","Single Cell Type RNA - Urothelial cells [nTPM]":"107.3"},{"Gene":"GLUL","Gene synonym":["GLNS"],"Ensembl":"ENSG00000135821","Gene description":"Glutamate-ammonia ligase","Uniprot":["P15104"],"Chromosome":"1","Position":"182378098-182392206","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Angiogenesis"],"Molecular function":["Ligase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"1443.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"8544.2","Muller glia cells":"6247.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"365.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"656.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"656.8"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"1150.8","ASC TERT1":"807.6","HSkMC":"702.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007316","HPA007571","CAB008636"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"150000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Mitochondria","Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB008636":"AB_1616669","HPA007316":"AB_888438","HPA007571":"AB_1078980"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.81e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-3"},"Tissue RNA - adipose tissue [nTPM]":"753.5","Tissue RNA - adrenal gland [nTPM]":"76.0","Tissue RNA - amygdala [nTPM]":"694.3","Tissue RNA - appendix [nTPM]":"156.9","Tissue RNA - basal ganglia [nTPM]":"746.5","Tissue RNA - bone marrow [nTPM]":"232.9","Tissue RNA - breast [nTPM]":"573.5","Tissue RNA - cerebellum [nTPM]":"717.5","Tissue RNA - cerebral cortex [nTPM]":"1237.1","Tissue RNA - cervix [nTPM]":"161.4","Tissue RNA - choroid plexus [nTPM]":"583.2","Tissue RNA - colon [nTPM]":"157.8","Tissue RNA - duodenum [nTPM]":"24.4","Tissue RNA - endometrium 1 [nTPM]":"116.7","Tissue RNA - epididymis [nTPM]":"115.7","Tissue RNA - esophagus [nTPM]":"218.7","Tissue RNA - fallopian tube [nTPM]":"224.3","Tissue RNA - gallbladder [nTPM]":"105.4","Tissue RNA - heart muscle [nTPM]":"129.7","Tissue RNA - hippocampal formation [nTPM]":"676.6","Tissue RNA - hypothalamus [nTPM]":"764.7","Tissue RNA - kidney [nTPM]":"65.3","Tissue RNA - liver [nTPM]":"280.7","Tissue RNA - lung [nTPM]":"221.7","Tissue RNA - lymph node [nTPM]":"75.2","Tissue RNA - medulla oblongata [nTPM]":"891.0","Tissue RNA - midbrain [nTPM]":"783.7","Tissue RNA - ovary [nTPM]":"303.0","Tissue RNA - pancreas [nTPM]":"204.7","Tissue RNA - parathyroid gland [nTPM]":"32.3","Tissue RNA - pituitary gland [nTPM]":"70.5","Tissue RNA - placenta [nTPM]":"176.6","Tissue RNA - pons [nTPM]":"767.0","Tissue RNA - prostate [nTPM]":"103.4","Tissue RNA - rectum [nTPM]":"92.5","Tissue RNA - retina [nTPM]":"891.1","Tissue RNA - salivary gland [nTPM]":"233.5","Tissue RNA - seminal vesicle [nTPM]":"96.0","Tissue RNA - skeletal muscle [nTPM]":"1443.6","Tissue RNA - skin 1 [nTPM]":"231.4","Tissue RNA - small intestine [nTPM]":"148.2","Tissue RNA - smooth muscle [nTPM]":"124.1","Tissue RNA - spinal cord [nTPM]":"725.0","Tissue RNA - spleen [nTPM]":"216.4","Tissue RNA - stomach 1 [nTPM]":"648.2","Tissue RNA - testis [nTPM]":"87.1","Tissue RNA - thalamus [nTPM]":"811.4","Tissue RNA - thymus [nTPM]":"97.0","Tissue RNA - thyroid gland [nTPM]":"257.4","Tissue RNA - tongue [nTPM]":"472.0","Tissue RNA - tonsil [nTPM]":"103.2","Tissue RNA - urinary bladder [nTPM]":"185.5","Tissue RNA - vagina [nTPM]":"292.0","Tissue RNA - white matter [nTPM]":"810.4","Cell RNA - A-431 [nTPM]":"26.4","Cell RNA - A549 [nTPM]":"10.8","Cell RNA - AF22 [nTPM]":"117.2","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"1150.8","Cell RNA - ASC TERT1 [nTPM]":"807.6","Cell RNA - BEWO [nTPM]":"86.0","Cell RNA - BJ [nTPM]":"44.1","Cell RNA - BJ hTERT+ [nTPM]":"141.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"25.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.4","Cell RNA - CACO-2 [nTPM]":"64.1","Cell RNA - CAPAN-2 [nTPM]":"26.7","Cell RNA - Daudi [nTPM]":"22.4","Cell RNA - EFO-21 [nTPM]":"46.3","Cell RNA - fHDF\/TERT166 [nTPM]":"85.5","Cell RNA - GAMG [nTPM]":"23.8","Cell RNA - HaCaT [nTPM]":"59.3","Cell RNA - HAP1 [nTPM]":"51.8","Cell RNA - HBEC3-KT [nTPM]":"309.4","Cell RNA - HBF TERT88 [nTPM]":"21.5","Cell RNA - HDLM-2 [nTPM]":"61.2","Cell RNA - HEK 293 [nTPM]":"143.3","Cell RNA - HEL [nTPM]":"296.5","Cell RNA - HeLa [nTPM]":"47.6","Cell RNA - Hep G2 [nTPM]":"124.8","Cell RNA - HHSteC [nTPM]":"61.1","Cell RNA - HL-60 [nTPM]":"132.6","Cell RNA - HMC-1 [nTPM]":"227.2","Cell RNA - HSkMC [nTPM]":"702.1","Cell RNA - hTCEpi [nTPM]":"363.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.9","Cell RNA - hTERT-HME1 [nTPM]":"384.6","Cell RNA - hTERT-RPE1 [nTPM]":"39.1","Cell RNA - HUVEC TERT2 [nTPM]":"52.8","Cell RNA - JURKAT [nTPM]":"71.7","Cell RNA - K-562 [nTPM]":"254.3","Cell RNA - Karpas-707 [nTPM]":"13.3","Cell RNA - LHCN-M2 [nTPM]":"92.6","Cell RNA - MCF7 [nTPM]":"15.0","Cell RNA - MOLT-4 [nTPM]":"208.2","Cell RNA - NB-4 [nTPM]":"126.5","Cell RNA - NTERA-2 [nTPM]":"87.3","Cell RNA - OE19 [nTPM]":"36.8","Cell RNA - PC-3 [nTPM]":"55.0","Cell RNA - REH [nTPM]":"74.3","Cell RNA - RH-30 [nTPM]":"31.3","Cell RNA - RPMI-8226 [nTPM]":"38.6","Cell RNA - RPTEC TERT1 [nTPM]":"45.8","Cell RNA - RT4 [nTPM]":"114.0","Cell RNA - SCLC-21H [nTPM]":"79.7","Cell RNA - SH-SY5Y [nTPM]":"52.5","Cell RNA - SiHa [nTPM]":"12.4","Cell RNA - SK-BR-3 [nTPM]":"157.3","Cell RNA - SK-MEL-30 [nTPM]":"17.4","Cell RNA - SuSa [nTPM]":"93.3","Cell RNA - T-47d [nTPM]":"153.1","Cell RNA - THP-1 [nTPM]":"165.9","Cell RNA - TIME [nTPM]":"39.7","Cell RNA - U-138 MG [nTPM]":"0.9","Cell RNA - U-2 OS [nTPM]":"1.9","Cell RNA - U-2197 [nTPM]":"0.8","Cell RNA - U-251 MG [nTPM]":"10.1","Cell RNA - U-266\/70 [nTPM]":"4.8","Cell RNA - U-266\/84 [nTPM]":"3.4","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"22.3","Cell RNA - U-937 [nTPM]":"73.9","Cell RNA - WM-115 [nTPM]":"5.0","Blood RNA - basophil [nTPM]":"396.5","Blood RNA - classical monocyte [nTPM]":"153.4","Blood RNA - eosinophil [nTPM]":"409.4","Blood RNA - gdT-cell [nTPM]":"42.3","Blood RNA - intermediate monocyte [nTPM]":"145.8","Blood RNA - MAIT T-cell [nTPM]":"17.6","Blood RNA - memory B-cell [nTPM]":"11.5","Blood RNA - memory CD4 T-cell [nTPM]":"29.9","Blood RNA - memory CD8 T-cell [nTPM]":"35.5","Blood RNA - myeloid DC [nTPM]":"80.0","Blood RNA - naive B-cell [nTPM]":"17.8","Blood RNA - naive CD4 T-cell [nTPM]":"15.3","Blood RNA - naive CD8 T-cell [nTPM]":"25.3","Blood RNA - neutrophil [nTPM]":"656.8","Blood RNA - NK-cell [nTPM]":"27.2","Blood RNA - non-classical monocyte [nTPM]":"130.5","Blood RNA - plasmacytoid DC [nTPM]":"43.7","Blood RNA - T-reg [nTPM]":"13.0","Blood RNA - total PBMC [nTPM]":"172.0","Brain RNA - amygdala [nTPM]":"694.3","Brain RNA - basal ganglia [nTPM]":"746.5","Brain RNA - cerebellum [nTPM]":"717.5","Brain RNA - cerebral cortex [nTPM]":"1237.1","Brain RNA - hippocampal formation [nTPM]":"676.6","Brain RNA - hypothalamus [nTPM]":"764.7","Brain RNA - medulla oblongata [nTPM]":"891.0","Brain RNA - midbrain [nTPM]":"783.7","Brain RNA - pons [nTPM]":"767.0","Brain RNA - spinal cord [nTPM]":"725.0","Brain RNA - thalamus [nTPM]":"811.4","Brain RNA - white matter [nTPM]":"810.4","Single Cell Type RNA - Adipocytes [nTPM]":"127.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"125.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"173.8","Single Cell Type RNA - Astrocytes [nTPM]":"599.4","Single Cell Type RNA - B-cells [nTPM]":"37.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"134.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"533.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1190.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"260.0","Single Cell Type RNA - Bipolar cells [nTPM]":"105.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"166.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"99.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"216.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"171.6","Single Cell Type RNA - Club cells [nTPM]":"855.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"82.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"161.7","Single Cell Type RNA - dendritic cells [nTPM]":"113.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"118.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"74.3","Single Cell Type RNA - Ductal cells [nTPM]":"124.2","Single Cell Type RNA - Early spermatids [nTPM]":"1491.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"140.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"150.0","Single Cell Type RNA - Endothelial cells [nTPM]":"191.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"325.9","Single Cell Type RNA - Erythroid cells [nTPM]":"319.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"116.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"65.9","Single Cell Type RNA - Fibroblasts [nTPM]":"404.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"388.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"124.6","Single Cell Type RNA - granulocytes [nTPM]":"786.3","Single Cell Type RNA - Granulosa cells [nTPM]":"88.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"152.8","Single Cell Type RNA - Hepatocytes [nTPM]":"597.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"798.0","Single Cell Type RNA - Horizontal cells [nTPM]":"43.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"256.7","Single Cell Type RNA - Ionocytes [nTPM]":"451.6","Single Cell Type RNA - Kupffer cells [nTPM]":"907.2","Single Cell Type RNA - Langerhans cells [nTPM]":"614.1","Single Cell Type RNA - Late spermatids [nTPM]":"8544.2","Single Cell Type RNA - Leydig cells [nTPM]":"487.4","Single Cell Type RNA - Macrophages [nTPM]":"687.4","Single Cell Type RNA - Melanocytes [nTPM]":"136.9","Single Cell Type RNA - Microglial cells [nTPM]":"74.9","Single Cell Type RNA - monocytes [nTPM]":"112.7","Single Cell Type RNA - Muller glia cells [nTPM]":"6247.0","Single Cell Type RNA - NK-cells [nTPM]":"42.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"38.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"330.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"108.1","Single Cell Type RNA - Paneth cells [nTPM]":"105.3","Single Cell Type RNA - Peritubular cells [nTPM]":"375.0","Single Cell Type RNA - Plasma cells [nTPM]":"38.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"421.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"46.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"569.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"176.0","Single Cell Type RNA - Sertoli cells [nTPM]":"92.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"481.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"218.5","Single Cell Type RNA - Spermatocytes [nTPM]":"48.2","Single Cell Type RNA - Spermatogonia [nTPM]":"63.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"186.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"128.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"235.3","Single Cell Type RNA - T-cells [nTPM]":"108.6","Single Cell Type RNA - Theca cells [nTPM]":"53.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"173.3","Single Cell Type RNA - Urothelial cells [nTPM]":"1420.5"},{"Gene":"GLYCTK","Gene synonym":["HBEBP2","HBEBP4"],"Ensembl":"ENSG00000168237","Gene description":"Glycerate kinase","Uniprot":["Q8IVS8"],"Chromosome":"3","Position":"52287089-52295257","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"liver":"275.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"183.0","Proximal enterocytes":"105.2","Proximal tubular cells":"83.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"liver cancer":"52.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006913"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol","Rods & Rings"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Cytosol"],"Subcellular additional location":["Golgi apparatus","Rods & Rings"],"Antibody RRID":{"HPA006913":"AB_1078993"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.64e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-3"},"Tissue RNA - adipose tissue [nTPM]":"14.8","Tissue RNA - adrenal gland [nTPM]":"8.3","Tissue RNA - amygdala [nTPM]":"1.0","Tissue RNA - appendix [nTPM]":"4.5","Tissue RNA - basal ganglia [nTPM]":"0.9","Tissue RNA - bone marrow [nTPM]":"6.7","Tissue RNA - breast [nTPM]":"9.3","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"1.5","Tissue RNA - cervix [nTPM]":"2.9","Tissue RNA - choroid plexus [nTPM]":"0.9","Tissue RNA - colon [nTPM]":"11.4","Tissue RNA - duodenum [nTPM]":"22.4","Tissue RNA - endometrium 1 [nTPM]":"3.2","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"3.8","Tissue RNA - fallopian tube [nTPM]":"2.7","Tissue RNA - gallbladder [nTPM]":"2.2","Tissue RNA - heart muscle [nTPM]":"4.4","Tissue RNA - hippocampal formation [nTPM]":"0.9","Tissue RNA - hypothalamus [nTPM]":"1.2","Tissue RNA - kidney [nTPM]":"24.9","Tissue RNA - liver [nTPM]":"275.1","Tissue RNA - lung [nTPM]":"4.2","Tissue RNA - lymph node [nTPM]":"4.6","Tissue RNA - medulla oblongata [nTPM]":"1.4","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"2.4","Tissue RNA - pancreas [nTPM]":"5.9","Tissue RNA - parathyroid gland [nTPM]":"2.5","Tissue RNA - pituitary gland [nTPM]":"2.9","Tissue RNA - placenta [nTPM]":"2.2","Tissue RNA - pons [nTPM]":"1.2","Tissue RNA - prostate [nTPM]":"3.7","Tissue RNA - rectum [nTPM]":"3.6","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"3.1","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"3.6","Tissue RNA - skin 1 [nTPM]":"1.9","Tissue RNA - small intestine [nTPM]":"21.7","Tissue RNA - smooth muscle [nTPM]":"1.6","Tissue RNA - spinal cord [nTPM]":"0.4","Tissue RNA - spleen [nTPM]":"8.9","Tissue RNA - stomach 1 [nTPM]":"8.5","Tissue RNA - testis [nTPM]":"2.3","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"2.3","Tissue RNA - thyroid gland [nTPM]":"4.1","Tissue RNA - tongue [nTPM]":"1.0","Tissue RNA - tonsil [nTPM]":"3.2","Tissue RNA - urinary bladder [nTPM]":"3.3","Tissue RNA - vagina [nTPM]":"2.5","Tissue RNA - white matter [nTPM]":"1.2","Cell RNA - A-431 [nTPM]":"2.9","Cell RNA - A549 [nTPM]":"5.8","Cell RNA - AF22 [nTPM]":"3.4","Cell RNA - AN3-CA [nTPM]":"1.2","Cell RNA - ASC diff [nTPM]":"15.7","Cell RNA - ASC TERT1 [nTPM]":"2.4","Cell RNA - BEWO [nTPM]":"1.8","Cell RNA - BJ [nTPM]":"2.4","Cell RNA - BJ hTERT+ [nTPM]":"2.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.9","Cell RNA - CACO-2 [nTPM]":"12.1","Cell RNA - CAPAN-2 [nTPM]":"2.4","Cell RNA - Daudi [nTPM]":"6.7","Cell RNA - EFO-21 [nTPM]":"1.6","Cell RNA - fHDF\/TERT166 [nTPM]":"2.7","Cell RNA - GAMG [nTPM]":"3.7","Cell RNA - HaCaT [nTPM]":"1.6","Cell RNA - HAP1 [nTPM]":"1.7","Cell RNA - HBEC3-KT [nTPM]":"7.8","Cell RNA - HBF TERT88 [nTPM]":"0.8","Cell RNA - HDLM-2 [nTPM]":"2.0","Cell RNA - HEK 293 [nTPM]":"1.8","Cell RNA - HEL [nTPM]":"9.3","Cell RNA - HeLa [nTPM]":"7.5","Cell RNA - Hep G2 [nTPM]":"16.2","Cell RNA - HHSteC [nTPM]":"1.7","Cell RNA - HL-60 [nTPM]":"2.8","Cell RNA - HMC-1 [nTPM]":"5.0","Cell RNA - HSkMC [nTPM]":"2.4","Cell RNA - hTCEpi [nTPM]":"3.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.6","Cell RNA - hTERT-HME1 [nTPM]":"3.2","Cell RNA - hTERT-RPE1 [nTPM]":"2.1","Cell RNA - HUVEC TERT2 [nTPM]":"10.2","Cell RNA - JURKAT [nTPM]":"5.2","Cell RNA - K-562 [nTPM]":"2.4","Cell RNA - Karpas-707 [nTPM]":"4.5","Cell RNA - LHCN-M2 [nTPM]":"3.6","Cell RNA - MCF7 [nTPM]":"1.9","Cell RNA - MOLT-4 [nTPM]":"5.9","Cell RNA - NB-4 [nTPM]":"2.7","Cell RNA - NTERA-2 [nTPM]":"1.5","Cell RNA - OE19 [nTPM]":"14.2","Cell RNA - PC-3 [nTPM]":"4.2","Cell RNA - REH [nTPM]":"1.9","Cell RNA - RH-30 [nTPM]":"2.5","Cell RNA - RPMI-8226 [nTPM]":"11.1","Cell RNA - RPTEC TERT1 [nTPM]":"5.8","Cell RNA - RT4 [nTPM]":"3.9","Cell RNA - SCLC-21H [nTPM]":"1.9","Cell RNA - SH-SY5Y [nTPM]":"1.9","Cell RNA - SiHa [nTPM]":"2.6","Cell RNA - SK-BR-3 [nTPM]":"1.4","Cell RNA - SK-MEL-30 [nTPM]":"3.0","Cell RNA - SuSa [nTPM]":"1.0","Cell RNA - T-47d [nTPM]":"3.2","Cell RNA - THP-1 [nTPM]":"1.7","Cell RNA - TIME [nTPM]":"3.8","Cell RNA - U-138 MG [nTPM]":"3.5","Cell RNA - U-2 OS [nTPM]":"4.1","Cell RNA - U-2197 [nTPM]":"2.4","Cell RNA - U-251 MG [nTPM]":"6.1","Cell RNA - U-266\/70 [nTPM]":"5.1","Cell RNA - U-266\/84 [nTPM]":"3.9","Cell RNA - U-698 [nTPM]":"5.4","Cell RNA - U-87 MG [nTPM]":"2.7","Cell RNA - U-937 [nTPM]":"4.9","Cell RNA - WM-115 [nTPM]":"2.2","Blood RNA - basophil [nTPM]":"2.2","Blood RNA - classical monocyte [nTPM]":"5.2","Blood RNA - eosinophil [nTPM]":"6.6","Blood RNA - gdT-cell [nTPM]":"5.6","Blood RNA - intermediate monocyte [nTPM]":"2.8","Blood RNA - MAIT T-cell [nTPM]":"2.6","Blood RNA - memory B-cell [nTPM]":"4.4","Blood RNA - memory CD4 T-cell [nTPM]":"4.2","Blood RNA - memory CD8 T-cell [nTPM]":"4.9","Blood RNA - myeloid DC [nTPM]":"5.6","Blood RNA - naive B-cell [nTPM]":"2.6","Blood RNA - naive CD4 T-cell [nTPM]":"3.3","Blood RNA - naive CD8 T-cell [nTPM]":"4.3","Blood RNA - neutrophil [nTPM]":"4.4","Blood RNA - NK-cell [nTPM]":"3.6","Blood RNA - non-classical monocyte [nTPM]":"3.5","Blood RNA - plasmacytoid DC [nTPM]":"3.4","Blood RNA - T-reg [nTPM]":"6.6","Blood RNA - total PBMC [nTPM]":"3.7","Brain RNA - amygdala [nTPM]":"1.0","Brain RNA - basal ganglia [nTPM]":"0.9","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"1.5","Brain RNA - hippocampal formation [nTPM]":"0.9","Brain RNA - hypothalamus [nTPM]":"1.2","Brain RNA - medulla oblongata [nTPM]":"1.4","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"1.2","Brain RNA - spinal cord [nTPM]":"0.4","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"1.2","Single Cell Type RNA - Adipocytes [nTPM]":"5.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"8.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"1.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"3.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.9","Single Cell Type RNA - dendritic cells [nTPM]":"9.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"5.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.7","Single Cell Type RNA - Endothelial cells [nTPM]":"8.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"23.4","Single Cell Type RNA - Erythroid cells [nTPM]":"26.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.3","Single Cell Type RNA - Fibroblasts [nTPM]":"2.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"27.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.6","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"3.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"183.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.8","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"16.6","Single Cell Type RNA - Langerhans cells [nTPM]":"2.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"9.1","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"7.7","Single Cell Type RNA - Muller glia cells [nTPM]":"1.2","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.0","Single Cell Type RNA - Paneth cells [nTPM]":"40.6","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"13.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"105.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"83.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.7","Single Cell Type RNA - Spermatocytes [nTPM]":"1.8","Single Cell Type RNA - Spermatogonia [nTPM]":"8.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.1","Single Cell Type RNA - T-cells [nTPM]":"9.3","Single Cell Type RNA - Theca cells [nTPM]":"7.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.9","Single Cell Type RNA - Urothelial cells [nTPM]":"4.3"},{"Gene":"GMPPB","Gene synonym":["KIAA1851"],"Ensembl":"ENSG00000173540","Gene description":"GDP-mannose pyrophosphorylase B","Uniprot":["Q9Y5P6"],"Chromosome":"3","Position":"49716844-49723973","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Nucleotidyltransferase","Transferase"],"Disease involvement":["Congenital muscular dystrophy","Disease variant","Dystroglycanopathy","Limb-girdle muscular dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"130.2","Syncytiotrophoblasts":"79.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014657"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"38000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014657":"AB_1849852"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.19e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.17e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Tissue RNA - adipose tissue [nTPM]":"14.5","Tissue RNA - adrenal gland [nTPM]":"30.1","Tissue RNA - amygdala [nTPM]":"6.1","Tissue RNA - appendix [nTPM]":"16.1","Tissue RNA - basal ganglia [nTPM]":"6.0","Tissue RNA - bone marrow [nTPM]":"11.8","Tissue RNA - breast [nTPM]":"15.3","Tissue RNA - cerebellum [nTPM]":"5.7","Tissue RNA - cerebral cortex [nTPM]":"6.6","Tissue RNA - cervix [nTPM]":"20.8","Tissue RNA - choroid plexus [nTPM]":"9.2","Tissue RNA - colon [nTPM]":"23.1","Tissue RNA - duodenum [nTPM]":"14.5","Tissue RNA - endometrium 1 [nTPM]":"18.6","Tissue RNA - epididymis [nTPM]":"14.5","Tissue RNA - esophagus [nTPM]":"26.3","Tissue RNA - fallopian tube [nTPM]":"19.5","Tissue RNA - gallbladder [nTPM]":"9.5","Tissue RNA - heart muscle [nTPM]":"18.2","Tissue RNA - hippocampal formation [nTPM]":"6.0","Tissue RNA - hypothalamus [nTPM]":"6.3","Tissue RNA - kidney [nTPM]":"17.5","Tissue RNA - liver [nTPM]":"44.2","Tissue RNA - lung [nTPM]":"21.4","Tissue RNA - lymph node [nTPM]":"13.0","Tissue RNA - medulla oblongata [nTPM]":"6.7","Tissue RNA - midbrain [nTPM]":"6.5","Tissue RNA - ovary [nTPM]":"14.0","Tissue RNA - pancreas [nTPM]":"57.4","Tissue RNA - parathyroid gland [nTPM]":"10.1","Tissue RNA - pituitary gland [nTPM]":"39.4","Tissue RNA - placenta [nTPM]":"7.5","Tissue RNA - pons [nTPM]":"6.1","Tissue RNA - prostate [nTPM]":"27.9","Tissue RNA - rectum [nTPM]":"12.2","Tissue RNA - retina [nTPM]":"4.1","Tissue RNA - salivary gland [nTPM]":"35.4","Tissue RNA - seminal vesicle [nTPM]":"14.7","Tissue RNA - skeletal muscle [nTPM]":"13.4","Tissue RNA - skin 1 [nTPM]":"14.9","Tissue RNA - small intestine [nTPM]":"21.8","Tissue RNA - smooth muscle [nTPM]":"9.4","Tissue RNA - spinal cord [nTPM]":"6.1","Tissue RNA - spleen [nTPM]":"27.9","Tissue RNA - stomach 1 [nTPM]":"26.2","Tissue RNA - testis [nTPM]":"9.6","Tissue RNA - thalamus [nTPM]":"6.8","Tissue RNA - thymus [nTPM]":"9.3","Tissue RNA - thyroid gland [nTPM]":"26.3","Tissue RNA - tongue [nTPM]":"5.7","Tissue RNA - tonsil [nTPM]":"13.0","Tissue RNA - urinary bladder [nTPM]":"15.9","Tissue RNA - vagina [nTPM]":"16.8","Tissue RNA - white matter [nTPM]":"5.9","Cell RNA - A-431 [nTPM]":"31.8","Cell RNA - A549 [nTPM]":"27.0","Cell RNA - AF22 [nTPM]":"21.0","Cell RNA - AN3-CA [nTPM]":"12.3","Cell RNA - ASC diff [nTPM]":"15.6","Cell RNA - ASC TERT1 [nTPM]":"10.8","Cell RNA - BEWO [nTPM]":"21.7","Cell RNA - BJ [nTPM]":"36.1","Cell RNA - BJ hTERT+ [nTPM]":"17.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"29.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"26.1","Cell RNA - CACO-2 [nTPM]":"18.7","Cell RNA - CAPAN-2 [nTPM]":"21.5","Cell RNA - Daudi [nTPM]":"17.6","Cell RNA - EFO-21 [nTPM]":"15.8","Cell RNA - fHDF\/TERT166 [nTPM]":"18.1","Cell RNA - GAMG [nTPM]":"22.2","Cell RNA - HaCaT [nTPM]":"16.7","Cell RNA - HAP1 [nTPM]":"18.6","Cell RNA - HBEC3-KT [nTPM]":"29.0","Cell RNA - HBF TERT88 [nTPM]":"10.6","Cell RNA - HDLM-2 [nTPM]":"17.2","Cell RNA - HEK 293 [nTPM]":"14.5","Cell RNA - HEL [nTPM]":"13.5","Cell RNA - HeLa [nTPM]":"27.2","Cell RNA - Hep G2 [nTPM]":"21.5","Cell RNA - HHSteC [nTPM]":"31.1","Cell RNA - HL-60 [nTPM]":"19.0","Cell RNA - HMC-1 [nTPM]":"19.6","Cell RNA - HSkMC [nTPM]":"8.2","Cell RNA - hTCEpi [nTPM]":"15.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"40.0","Cell RNA - hTERT-HME1 [nTPM]":"34.8","Cell RNA - hTERT-RPE1 [nTPM]":"11.3","Cell RNA - HUVEC TERT2 [nTPM]":"24.8","Cell RNA - JURKAT [nTPM]":"20.2","Cell RNA - K-562 [nTPM]":"10.4","Cell RNA - Karpas-707 [nTPM]":"32.0","Cell RNA - LHCN-M2 [nTPM]":"16.3","Cell RNA - MCF7 [nTPM]":"20.3","Cell RNA - MOLT-4 [nTPM]":"27.3","Cell RNA - NB-4 [nTPM]":"11.7","Cell RNA - NTERA-2 [nTPM]":"12.2","Cell RNA - OE19 [nTPM]":"22.5","Cell RNA - PC-3 [nTPM]":"34.3","Cell RNA - REH [nTPM]":"9.2","Cell RNA - RH-30 [nTPM]":"12.5","Cell RNA - RPMI-8226 [nTPM]":"30.4","Cell RNA - RPTEC TERT1 [nTPM]":"16.3","Cell RNA - RT4 [nTPM]":"24.0","Cell RNA - SCLC-21H [nTPM]":"13.8","Cell RNA - SH-SY5Y [nTPM]":"16.0","Cell RNA - SiHa [nTPM]":"15.7","Cell RNA - SK-BR-3 [nTPM]":"36.5","Cell RNA - SK-MEL-30 [nTPM]":"12.5","Cell RNA - SuSa [nTPM]":"10.6","Cell RNA - T-47d [nTPM]":"20.6","Cell RNA - THP-1 [nTPM]":"13.9","Cell RNA - TIME [nTPM]":"21.9","Cell RNA - U-138 MG [nTPM]":"25.7","Cell RNA - U-2 OS [nTPM]":"25.0","Cell RNA - U-2197 [nTPM]":"33.4","Cell RNA - U-251 MG [nTPM]":"38.8","Cell RNA - U-266\/70 [nTPM]":"33.7","Cell RNA - U-266\/84 [nTPM]":"11.1","Cell RNA - U-698 [nTPM]":"13.6","Cell RNA - U-87 MG [nTPM]":"25.4","Cell RNA - U-937 [nTPM]":"14.7","Cell RNA - WM-115 [nTPM]":"28.6","Blood RNA - basophil [nTPM]":"22.1","Blood RNA - classical monocyte [nTPM]":"15.6","Blood RNA - eosinophil [nTPM]":"6.7","Blood RNA - gdT-cell [nTPM]":"18.3","Blood RNA - intermediate monocyte [nTPM]":"21.3","Blood RNA - MAIT T-cell [nTPM]":"18.6","Blood RNA - memory B-cell [nTPM]":"22.7","Blood RNA - memory CD4 T-cell [nTPM]":"15.9","Blood RNA - memory CD8 T-cell [nTPM]":"19.3","Blood RNA - myeloid DC [nTPM]":"14.7","Blood RNA - naive B-cell [nTPM]":"22.5","Blood RNA - naive CD4 T-cell [nTPM]":"11.8","Blood RNA - naive CD8 T-cell [nTPM]":"14.6","Blood RNA - neutrophil [nTPM]":"4.0","Blood RNA - NK-cell [nTPM]":"11.3","Blood RNA - non-classical monocyte [nTPM]":"21.8","Blood RNA - plasmacytoid DC [nTPM]":"61.8","Blood RNA - T-reg [nTPM]":"12.0","Blood RNA - total PBMC [nTPM]":"14.8","Brain RNA - amygdala [nTPM]":"6.1","Brain RNA - basal ganglia [nTPM]":"6.0","Brain RNA - cerebellum [nTPM]":"5.7","Brain RNA - cerebral cortex [nTPM]":"6.6","Brain RNA - hippocampal formation [nTPM]":"6.0","Brain RNA - hypothalamus [nTPM]":"6.3","Brain RNA - medulla oblongata [nTPM]":"6.7","Brain RNA - midbrain [nTPM]":"6.5","Brain RNA - pons [nTPM]":"6.1","Brain RNA - spinal cord [nTPM]":"6.1","Brain RNA - thalamus [nTPM]":"6.8","Brain RNA - white matter [nTPM]":"5.9","Single Cell Type RNA - Adipocytes [nTPM]":"7.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.2","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"35.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"3.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"34.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"3.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"28.5","Single Cell Type RNA - dendritic cells [nTPM]":"28.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"43.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"29.4","Single Cell Type RNA - Ductal cells [nTPM]":"39.8","Single Cell Type RNA - Early spermatids [nTPM]":"10.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.3","Single Cell Type RNA - Endothelial cells [nTPM]":"10.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.7","Single Cell Type RNA - Erythroid cells [nTPM]":"9.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"50.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"67.2","Single Cell Type RNA - Fibroblasts [nTPM]":"15.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"34.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"11.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.3","Single Cell Type RNA - Hepatocytes [nTPM]":"28.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"39.0","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"55.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"10.7","Single Cell Type RNA - Langerhans cells [nTPM]":"1.7","Single Cell Type RNA - Late spermatids [nTPM]":"10.0","Single Cell Type RNA - Leydig cells [nTPM]":"15.5","Single Cell Type RNA - Macrophages [nTPM]":"13.7","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"40.9","Single Cell Type RNA - Muller glia cells [nTPM]":"5.8","Single Cell Type RNA - NK-cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"31.9","Single Cell Type RNA - Paneth cells [nTPM]":"27.1","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"130.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"40.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"29.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"25.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.2","Single Cell Type RNA - Spermatocytes [nTPM]":"22.9","Single Cell Type RNA - Spermatogonia [nTPM]":"12.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"79.5","Single Cell Type RNA - T-cells [nTPM]":"14.7","Single Cell Type RNA - Theca cells [nTPM]":"13.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"32.8","Single Cell Type RNA - Urothelial cells [nTPM]":"37.1"},{"Gene":"GMPS","Gene synonym":["GATD7"],"Ensembl":"ENSG00000163655","Gene description":"Guanine monophosphate synthase","Uniprot":["P49915"],"Chromosome":"3","Position":"155870650-155944020","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["GMP biosynthesis","Purine biosynthesis"],"Molecular function":["Ligase"],"Disease involvement":["Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"100.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"272.7","Late spermatids":"193.6","Spermatocytes":"171.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046630"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"50000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA046630":"AB_2679727"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.54e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.73e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.04e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.79e-2"},"Tissue RNA - adipose tissue [nTPM]":"18.8","Tissue RNA - adrenal gland [nTPM]":"20.7","Tissue RNA - amygdala [nTPM]":"7.2","Tissue RNA - appendix [nTPM]":"20.0","Tissue RNA - basal ganglia [nTPM]":"7.7","Tissue RNA - bone marrow [nTPM]":"44.6","Tissue RNA - breast [nTPM]":"24.1","Tissue RNA - cerebellum [nTPM]":"22.7","Tissue RNA - cerebral cortex [nTPM]":"11.0","Tissue RNA - cervix [nTPM]":"21.2","Tissue RNA - choroid plexus [nTPM]":"7.9","Tissue RNA - colon [nTPM]":"19.7","Tissue RNA - duodenum [nTPM]":"15.8","Tissue RNA - endometrium 1 [nTPM]":"20.6","Tissue RNA - epididymis [nTPM]":"16.0","Tissue RNA - esophagus [nTPM]":"22.1","Tissue RNA - fallopian tube [nTPM]":"17.1","Tissue RNA - gallbladder [nTPM]":"14.0","Tissue RNA - heart muscle [nTPM]":"17.9","Tissue RNA - hippocampal formation [nTPM]":"6.8","Tissue RNA - hypothalamus [nTPM]":"8.5","Tissue RNA - kidney [nTPM]":"15.9","Tissue RNA - liver [nTPM]":"22.6","Tissue RNA - lung [nTPM]":"18.2","Tissue RNA - lymph node [nTPM]":"27.0","Tissue RNA - medulla oblongata [nTPM]":"7.8","Tissue RNA - midbrain [nTPM]":"6.8","Tissue RNA - ovary [nTPM]":"17.0","Tissue RNA - pancreas [nTPM]":"26.4","Tissue RNA - parathyroid gland [nTPM]":"23.1","Tissue RNA - pituitary gland [nTPM]":"11.5","Tissue RNA - placenta [nTPM]":"20.8","Tissue RNA - pons [nTPM]":"8.3","Tissue RNA - prostate [nTPM]":"17.4","Tissue RNA - rectum [nTPM]":"22.5","Tissue RNA - retina [nTPM]":"10.1","Tissue RNA - salivary gland [nTPM]":"20.9","Tissue RNA - seminal vesicle [nTPM]":"17.5","Tissue RNA - skeletal muscle [nTPM]":"20.0","Tissue RNA - skin 1 [nTPM]":"25.0","Tissue RNA - small intestine [nTPM]":"16.7","Tissue RNA - smooth muscle [nTPM]":"23.4","Tissue RNA - spinal cord [nTPM]":"6.3","Tissue RNA - spleen [nTPM]":"19.2","Tissue RNA - stomach 1 [nTPM]":"18.0","Tissue RNA - testis [nTPM]":"100.3","Tissue RNA - thalamus [nTPM]":"8.0","Tissue RNA - thymus [nTPM]":"32.3","Tissue RNA - thyroid gland [nTPM]":"20.3","Tissue RNA - tongue [nTPM]":"16.7","Tissue RNA - tonsil [nTPM]":"29.4","Tissue RNA - urinary bladder [nTPM]":"23.3","Tissue RNA - vagina [nTPM]":"19.9","Tissue RNA - white matter [nTPM]":"8.8","Cell RNA - A-431 [nTPM]":"241.0","Cell RNA - A549 [nTPM]":"93.1","Cell RNA - AF22 [nTPM]":"123.0","Cell RNA - AN3-CA [nTPM]":"101.1","Cell RNA - ASC diff [nTPM]":"49.0","Cell RNA - ASC TERT1 [nTPM]":"77.0","Cell RNA - BEWO [nTPM]":"118.9","Cell RNA - BJ [nTPM]":"99.8","Cell RNA - BJ hTERT+ [nTPM]":"91.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"128.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"128.8","Cell RNA - CACO-2 [nTPM]":"170.5","Cell RNA - CAPAN-2 [nTPM]":"156.2","Cell RNA - Daudi [nTPM]":"171.7","Cell RNA - EFO-21 [nTPM]":"116.1","Cell RNA - fHDF\/TERT166 [nTPM]":"77.1","Cell RNA - GAMG [nTPM]":"98.1","Cell RNA - HaCaT [nTPM]":"114.6","Cell RNA - HAP1 [nTPM]":"105.7","Cell RNA - HBEC3-KT [nTPM]":"104.2","Cell RNA - HBF TERT88 [nTPM]":"175.0","Cell RNA - HDLM-2 [nTPM]":"101.1","Cell RNA - HEK 293 [nTPM]":"81.8","Cell RNA - HEL [nTPM]":"183.2","Cell RNA - HeLa [nTPM]":"63.7","Cell RNA - Hep G2 [nTPM]":"92.8","Cell RNA - HHSteC [nTPM]":"55.9","Cell RNA - HL-60 [nTPM]":"188.5","Cell RNA - HMC-1 [nTPM]":"68.7","Cell RNA - HSkMC [nTPM]":"57.3","Cell RNA - hTCEpi [nTPM]":"62.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"99.4","Cell RNA - hTERT-HME1 [nTPM]":"150.5","Cell RNA - hTERT-RPE1 [nTPM]":"68.2","Cell RNA - HUVEC TERT2 [nTPM]":"79.9","Cell RNA - JURKAT [nTPM]":"91.3","Cell RNA - K-562 [nTPM]":"131.7","Cell RNA - Karpas-707 [nTPM]":"63.8","Cell RNA - LHCN-M2 [nTPM]":"96.8","Cell RNA - MCF7 [nTPM]":"160.1","Cell RNA - MOLT-4 [nTPM]":"153.9","Cell RNA - NB-4 [nTPM]":"99.4","Cell RNA - NTERA-2 [nTPM]":"118.5","Cell RNA - OE19 [nTPM]":"130.4","Cell RNA - PC-3 [nTPM]":"68.3","Cell RNA - REH [nTPM]":"149.2","Cell RNA - RH-30 [nTPM]":"145.8","Cell RNA - RPMI-8226 [nTPM]":"207.5","Cell RNA - RPTEC TERT1 [nTPM]":"66.3","Cell RNA - RT4 [nTPM]":"103.5","Cell RNA - SCLC-21H [nTPM]":"73.3","Cell RNA - SH-SY5Y [nTPM]":"68.0","Cell RNA - SiHa [nTPM]":"111.0","Cell RNA - SK-BR-3 [nTPM]":"156.0","Cell RNA - SK-MEL-30 [nTPM]":"101.8","Cell RNA - SuSa [nTPM]":"83.9","Cell RNA - T-47d [nTPM]":"163.6","Cell RNA - THP-1 [nTPM]":"122.3","Cell RNA - TIME [nTPM]":"56.9","Cell RNA - U-138 MG [nTPM]":"84.4","Cell RNA - U-2 OS [nTPM]":"68.5","Cell RNA - U-2197 [nTPM]":"121.0","Cell RNA - U-251 MG [nTPM]":"204.3","Cell RNA - U-266\/70 [nTPM]":"88.8","Cell RNA - U-266\/84 [nTPM]":"58.5","Cell RNA - U-698 [nTPM]":"288.5","Cell RNA - U-87 MG [nTPM]":"84.8","Cell RNA - U-937 [nTPM]":"137.4","Cell RNA - WM-115 [nTPM]":"77.0","Blood RNA - basophil [nTPM]":"23.7","Blood RNA - classical monocyte [nTPM]":"16.1","Blood RNA - eosinophil [nTPM]":"11.5","Blood RNA - gdT-cell [nTPM]":"24.7","Blood RNA - intermediate monocyte [nTPM]":"20.2","Blood RNA - MAIT T-cell [nTPM]":"29.1","Blood RNA - memory B-cell [nTPM]":"16.0","Blood RNA - memory CD4 T-cell [nTPM]":"23.6","Blood RNA - memory CD8 T-cell [nTPM]":"22.3","Blood RNA - myeloid DC [nTPM]":"26.1","Blood RNA - naive B-cell [nTPM]":"11.6","Blood RNA - naive CD4 T-cell [nTPM]":"23.3","Blood RNA - naive CD8 T-cell [nTPM]":"22.3","Blood RNA - neutrophil [nTPM]":"2.2","Blood RNA - NK-cell [nTPM]":"29.3","Blood RNA - non-classical monocyte [nTPM]":"29.5","Blood RNA - plasmacytoid DC [nTPM]":"14.2","Blood RNA - T-reg [nTPM]":"27.1","Blood RNA - total PBMC [nTPM]":"17.5","Brain RNA - amygdala [nTPM]":"7.2","Brain RNA - basal ganglia [nTPM]":"7.7","Brain RNA - cerebellum [nTPM]":"22.7","Brain RNA - cerebral cortex [nTPM]":"11.0","Brain RNA - hippocampal formation [nTPM]":"6.8","Brain RNA - hypothalamus [nTPM]":"8.5","Brain RNA - medulla oblongata [nTPM]":"7.8","Brain RNA - midbrain [nTPM]":"6.8","Brain RNA - pons [nTPM]":"8.3","Brain RNA - spinal cord [nTPM]":"6.3","Brain RNA - thalamus [nTPM]":"8.0","Brain RNA - white matter [nTPM]":"8.8","Single Cell Type RNA - Adipocytes [nTPM]":"23.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.2","Single Cell Type RNA - Astrocytes [nTPM]":"19.6","Single Cell Type RNA - B-cells [nTPM]":"21.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"39.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"47.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"43.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.8","Single Cell Type RNA - Bipolar cells [nTPM]":"22.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"28.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"44.1","Single Cell Type RNA - dendritic cells [nTPM]":"21.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"25.4","Single Cell Type RNA - Ductal cells [nTPM]":"33.8","Single Cell Type RNA - Early spermatids [nTPM]":"272.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"37.5","Single Cell Type RNA - Endothelial cells [nTPM]":"29.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"68.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"40.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"29.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"56.2","Single Cell Type RNA - Fibroblasts [nTPM]":"32.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.4","Single Cell Type RNA - granulocytes [nTPM]":"28.6","Single Cell Type RNA - Granulosa cells [nTPM]":"34.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.1","Single Cell Type RNA - Hepatocytes [nTPM]":"11.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"29.9","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"41.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.7","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"18.5","Single Cell Type RNA - Langerhans cells [nTPM]":"27.1","Single Cell Type RNA - Late spermatids [nTPM]":"193.6","Single Cell Type RNA - Leydig cells [nTPM]":"23.0","Single Cell Type RNA - Macrophages [nTPM]":"25.2","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"22.5","Single Cell Type RNA - monocytes [nTPM]":"31.7","Single Cell Type RNA - Muller glia cells [nTPM]":"17.8","Single Cell Type RNA - NK-cells [nTPM]":"30.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"30.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"31.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.3","Single Cell Type RNA - Paneth cells [nTPM]":"11.9","Single Cell Type RNA - Peritubular cells [nTPM]":"24.8","Single Cell Type RNA - Plasma cells [nTPM]":"21.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"50.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.7","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"28.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"65.2","Single Cell Type RNA - Spermatocytes [nTPM]":"171.2","Single Cell Type RNA - Spermatogonia [nTPM]":"65.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"29.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"38.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"30.8","Single Cell Type RNA - T-cells [nTPM]":"30.4","Single Cell Type RNA - Theca cells [nTPM]":"63.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.8","Single Cell Type RNA - Urothelial cells [nTPM]":"42.4"},{"Gene":"GNA11","Gene synonym":["FBH","FBH2","FHH2","HHC2"],"Ensembl":"ENSG00000088256","Gene description":"G protein subunit alpha 11","Uniprot":["P29992"],"Chromosome":"19","Position":"3094362-3123999","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":["Transducer"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"330.6","Proximal enterocytes":"323.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"5.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048886"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA048886":"AB_2680544"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.86e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.48e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Tissue RNA - adipose tissue [nTPM]":"33.5","Tissue RNA - adrenal gland [nTPM]":"32.5","Tissue RNA - amygdala [nTPM]":"36.4","Tissue RNA - appendix [nTPM]":"16.2","Tissue RNA - basal ganglia [nTPM]":"31.2","Tissue RNA - bone marrow [nTPM]":"8.3","Tissue RNA - breast [nTPM]":"32.6","Tissue RNA - cerebellum [nTPM]":"53.8","Tissue RNA - cerebral cortex [nTPM]":"35.3","Tissue RNA - cervix [nTPM]":"31.7","Tissue RNA - choroid plexus [nTPM]":"18.9","Tissue RNA - colon [nTPM]":"66.7","Tissue RNA - duodenum [nTPM]":"117.5","Tissue RNA - endometrium 1 [nTPM]":"42.4","Tissue RNA - epididymis [nTPM]":"12.7","Tissue RNA - esophagus [nTPM]":"28.7","Tissue RNA - fallopian tube [nTPM]":"44.5","Tissue RNA - gallbladder [nTPM]":"20.0","Tissue RNA - heart muscle [nTPM]":"51.7","Tissue RNA - hippocampal formation [nTPM]":"33.5","Tissue RNA - hypothalamus [nTPM]":"27.3","Tissue RNA - kidney [nTPM]":"40.4","Tissue RNA - liver [nTPM]":"26.2","Tissue RNA - lung [nTPM]":"34.7","Tissue RNA - lymph node [nTPM]":"7.5","Tissue RNA - medulla oblongata [nTPM]":"30.3","Tissue RNA - midbrain [nTPM]":"29.6","Tissue RNA - ovary [nTPM]":"32.5","Tissue RNA - pancreas [nTPM]":"33.9","Tissue RNA - parathyroid gland [nTPM]":"26.3","Tissue RNA - pituitary gland [nTPM]":"29.8","Tissue RNA - placenta [nTPM]":"22.3","Tissue RNA - pons [nTPM]":"28.6","Tissue RNA - prostate [nTPM]":"40.4","Tissue RNA - rectum [nTPM]":"38.7","Tissue RNA - retina [nTPM]":"11.0","Tissue RNA - salivary gland [nTPM]":"33.3","Tissue RNA - seminal vesicle [nTPM]":"47.1","Tissue RNA - skeletal muscle [nTPM]":"54.2","Tissue RNA - skin 1 [nTPM]":"34.4","Tissue RNA - small intestine [nTPM]":"139.3","Tissue RNA - smooth muscle [nTPM]":"28.7","Tissue RNA - spinal cord [nTPM]":"26.6","Tissue RNA - spleen [nTPM]":"21.4","Tissue RNA - stomach 1 [nTPM]":"34.9","Tissue RNA - testis [nTPM]":"50.6","Tissue RNA - thalamus [nTPM]":"31.3","Tissue RNA - thymus [nTPM]":"8.5","Tissue RNA - thyroid gland [nTPM]":"32.9","Tissue RNA - tongue [nTPM]":"39.2","Tissue RNA - tonsil [nTPM]":"7.0","Tissue RNA - urinary bladder [nTPM]":"38.8","Tissue RNA - vagina [nTPM]":"27.0","Tissue RNA - white matter [nTPM]":"31.1","Cell RNA - A-431 [nTPM]":"56.1","Cell RNA - A549 [nTPM]":"31.2","Cell RNA - AF22 [nTPM]":"27.9","Cell RNA - AN3-CA [nTPM]":"48.5","Cell RNA - ASC diff [nTPM]":"41.7","Cell RNA - ASC TERT1 [nTPM]":"28.4","Cell RNA - BEWO [nTPM]":"30.9","Cell RNA - BJ [nTPM]":"53.8","Cell RNA - BJ hTERT+ [nTPM]":"53.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"71.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"57.8","Cell RNA - CACO-2 [nTPM]":"41.7","Cell RNA - CAPAN-2 [nTPM]":"27.3","Cell RNA - Daudi [nTPM]":"12.0","Cell RNA - EFO-21 [nTPM]":"29.2","Cell RNA - fHDF\/TERT166 [nTPM]":"76.4","Cell RNA - GAMG [nTPM]":"43.6","Cell RNA - HaCaT [nTPM]":"39.0","Cell RNA - HAP1 [nTPM]":"37.8","Cell RNA - HBEC3-KT [nTPM]":"42.7","Cell RNA - HBF TERT88 [nTPM]":"44.3","Cell RNA - HDLM-2 [nTPM]":"30.1","Cell RNA - HEK 293 [nTPM]":"21.9","Cell RNA - HEL [nTPM]":"3.3","Cell RNA - HeLa [nTPM]":"35.7","Cell RNA - Hep G2 [nTPM]":"23.6","Cell RNA - HHSteC [nTPM]":"42.2","Cell RNA - HL-60 [nTPM]":"3.8","Cell RNA - HMC-1 [nTPM]":"11.8","Cell RNA - HSkMC [nTPM]":"36.9","Cell RNA - hTCEpi [nTPM]":"36.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"48.4","Cell RNA - hTERT-HME1 [nTPM]":"29.2","Cell RNA - hTERT-RPE1 [nTPM]":"36.9","Cell RNA - HUVEC TERT2 [nTPM]":"57.8","Cell RNA - JURKAT [nTPM]":"3.4","Cell RNA - K-562 [nTPM]":"27.8","Cell RNA - Karpas-707 [nTPM]":"1.9","Cell RNA - LHCN-M2 [nTPM]":"49.1","Cell RNA - MCF7 [nTPM]":"25.8","Cell RNA - MOLT-4 [nTPM]":"3.0","Cell RNA - NB-4 [nTPM]":"14.4","Cell RNA - NTERA-2 [nTPM]":"20.5","Cell RNA - OE19 [nTPM]":"38.4","Cell RNA - PC-3 [nTPM]":"29.4","Cell RNA - REH [nTPM]":"23.2","Cell RNA - RH-30 [nTPM]":"26.4","Cell RNA - RPMI-8226 [nTPM]":"11.9","Cell RNA - RPTEC TERT1 [nTPM]":"33.8","Cell RNA - RT4 [nTPM]":"40.8","Cell RNA - SCLC-21H [nTPM]":"66.0","Cell RNA - SH-SY5Y [nTPM]":"40.7","Cell RNA - SiHa [nTPM]":"38.3","Cell RNA - SK-BR-3 [nTPM]":"45.2","Cell RNA - SK-MEL-30 [nTPM]":"27.2","Cell RNA - SuSa [nTPM]":"18.9","Cell RNA - T-47d [nTPM]":"33.3","Cell RNA - THP-1 [nTPM]":"7.9","Cell RNA - TIME [nTPM]":"50.0","Cell RNA - U-138 MG [nTPM]":"45.7","Cell RNA - U-2 OS [nTPM]":"33.3","Cell RNA - U-2197 [nTPM]":"85.4","Cell RNA - U-251 MG [nTPM]":"73.5","Cell RNA - U-266\/70 [nTPM]":"1.3","Cell RNA - U-266\/84 [nTPM]":"3.9","Cell RNA - U-698 [nTPM]":"7.9","Cell RNA - U-87 MG [nTPM]":"33.0","Cell RNA - U-937 [nTPM]":"2.9","Cell RNA - WM-115 [nTPM]":"52.3","Blood RNA - basophil [nTPM]":"2.5","Blood RNA - classical monocyte [nTPM]":"1.4","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"5.1","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"1.5","Blood RNA - plasmacytoid DC [nTPM]":"2.3","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"36.4","Brain RNA - basal ganglia [nTPM]":"31.2","Brain RNA - cerebellum [nTPM]":"53.8","Brain RNA - cerebral cortex [nTPM]":"35.3","Brain RNA - hippocampal formation [nTPM]":"33.5","Brain RNA - hypothalamus [nTPM]":"27.3","Brain RNA - medulla oblongata [nTPM]":"30.3","Brain RNA - midbrain [nTPM]":"29.6","Brain RNA - pons [nTPM]":"28.6","Brain RNA - spinal cord [nTPM]":"26.6","Brain RNA - thalamus [nTPM]":"31.3","Brain RNA - white matter [nTPM]":"31.1","Single Cell Type RNA - Adipocytes [nTPM]":"62.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"24.1","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"3.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"32.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"22.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"43.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"47.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"35.8","Single Cell Type RNA - Club cells [nTPM]":"12.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.2","Single Cell Type RNA - dendritic cells [nTPM]":"2.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"330.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"21.4","Single Cell Type RNA - Early spermatids [nTPM]":"45.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"26.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.0","Single Cell Type RNA - Endothelial cells [nTPM]":"33.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"54.6","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.5","Single Cell Type RNA - Fibroblasts [nTPM]":"25.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"29.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.1","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"24.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"58.2","Single Cell Type RNA - Hepatocytes [nTPM]":"28.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.0","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"84.1","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"9.1","Single Cell Type RNA - Langerhans cells [nTPM]":"16.4","Single Cell Type RNA - Late spermatids [nTPM]":"20.0","Single Cell Type RNA - Leydig cells [nTPM]":"50.1","Single Cell Type RNA - Macrophages [nTPM]":"5.1","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"1.1","Single Cell Type RNA - Muller glia cells [nTPM]":"29.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"36.1","Single Cell Type RNA - Paneth cells [nTPM]":"96.0","Single Cell Type RNA - Peritubular cells [nTPM]":"80.5","Single Cell Type RNA - Plasma cells [nTPM]":"1.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"323.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"35.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.8","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"28.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"30.5","Single Cell Type RNA - Spermatocytes [nTPM]":"23.7","Single Cell Type RNA - Spermatogonia [nTPM]":"8.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"41.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.4","Single Cell Type RNA - T-cells [nTPM]":"2.0","Single Cell Type RNA - Theca cells [nTPM]":"22.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"94.9","Single Cell Type RNA - Urothelial cells [nTPM]":"13.4"},{"Gene":"GNAS","Gene synonym":["GNAS1","GNASXL","GPSA","NESP","NESP55","SCG6","SgVI"],"Ensembl":"ENSG00000087460","Gene description":"GNAS complex locus","Uniprot":["O95467","P63092","P84996","Q5JWF2"],"Chromosome":"20","Position":"58839718-58911192","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Transducer"],"Disease involvement":["Cancer-related genes","Cushing syndrome","Disease variant","Dwarfism","Obesity","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"1886.1","Late spermatids":"1756.9","Skeletal myocytes":"1998.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010337","HPA018122","HPA027478","HPA028386"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Plasma membrane","Cytosol"],"Antibody RRID":{"CAB010337":"AB_631538","HPA018122":"AB_1849236","HPA027478":"AB_10599284","HPA028386":"AB_10601983"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.76e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.49e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Tissue RNA - adipose tissue [nTPM]":"784.8","Tissue RNA - adrenal gland [nTPM]":"1215.3","Tissue RNA - amygdala [nTPM]":"1564.4","Tissue RNA - appendix [nTPM]":"512.6","Tissue RNA - basal ganglia [nTPM]":"1524.7","Tissue RNA - bone marrow [nTPM]":"887.4","Tissue RNA - breast [nTPM]":"578.9","Tissue RNA - cerebellum [nTPM]":"1413.1","Tissue RNA - cerebral cortex [nTPM]":"1768.3","Tissue RNA - cervix [nTPM]":"828.5","Tissue RNA - choroid plexus [nTPM]":"1373.3","Tissue RNA - colon [nTPM]":"657.1","Tissue RNA - duodenum [nTPM]":"492.4","Tissue RNA - endometrium 1 [nTPM]":"611.4","Tissue RNA - epididymis [nTPM]":"1253.8","Tissue RNA - esophagus [nTPM]":"883.1","Tissue RNA - fallopian tube [nTPM]":"742.9","Tissue RNA - gallbladder [nTPM]":"672.7","Tissue RNA - heart muscle [nTPM]":"1990.6","Tissue RNA - hippocampal formation [nTPM]":"1557.3","Tissue RNA - hypothalamus [nTPM]":"2716.9","Tissue RNA - kidney [nTPM]":"625.0","Tissue RNA - liver [nTPM]":"651.1","Tissue RNA - lung [nTPM]":"640.3","Tissue RNA - lymph node [nTPM]":"769.2","Tissue RNA - medulla oblongata [nTPM]":"1710.5","Tissue RNA - midbrain [nTPM]":"1949.4","Tissue RNA - ovary [nTPM]":"766.5","Tissue RNA - pancreas [nTPM]":"1917.7","Tissue RNA - parathyroid gland [nTPM]":"1799.4","Tissue RNA - pituitary gland [nTPM]":"1153.6","Tissue RNA - placenta [nTPM]":"884.6","Tissue RNA - pons [nTPM]":"1963.4","Tissue RNA - prostate [nTPM]":"577.3","Tissue RNA - rectum [nTPM]":"607.3","Tissue RNA - retina [nTPM]":"731.2","Tissue RNA - salivary gland [nTPM]":"2943.9","Tissue RNA - seminal vesicle [nTPM]":"594.4","Tissue RNA - skeletal muscle [nTPM]":"2400.4","Tissue RNA - skin 1 [nTPM]":"526.8","Tissue RNA - small intestine [nTPM]":"527.3","Tissue RNA - smooth muscle [nTPM]":"782.4","Tissue RNA - spinal cord [nTPM]":"1598.4","Tissue RNA - spleen [nTPM]":"606.6","Tissue RNA - stomach 1 [nTPM]":"587.1","Tissue RNA - testis [nTPM]":"357.9","Tissue RNA - thalamus [nTPM]":"1882.0","Tissue RNA - thymus [nTPM]":"854.4","Tissue RNA - thyroid gland [nTPM]":"3432.2","Tissue RNA - tongue [nTPM]":"2813.1","Tissue RNA - tonsil [nTPM]":"800.0","Tissue RNA - urinary bladder [nTPM]":"687.1","Tissue RNA - vagina [nTPM]":"239.3","Tissue RNA - white matter [nTPM]":"1483.9","Cell RNA - A-431 [nTPM]":"215.6","Cell RNA - A549 [nTPM]":"897.3","Cell RNA - AF22 [nTPM]":"1501.9","Cell RNA - AN3-CA [nTPM]":"663.3","Cell RNA - ASC diff [nTPM]":"2691.8","Cell RNA - ASC TERT1 [nTPM]":"1822.3","Cell RNA - BEWO [nTPM]":"1200.1","Cell RNA - BJ [nTPM]":"1219.1","Cell RNA - BJ hTERT+ [nTPM]":"1635.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1937.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1201.8","Cell RNA - CACO-2 [nTPM]":"2480.5","Cell RNA - CAPAN-2 [nTPM]":"1446.7","Cell RNA - Daudi [nTPM]":"911.9","Cell RNA - EFO-21 [nTPM]":"1670.3","Cell RNA - fHDF\/TERT166 [nTPM]":"2314.3","Cell RNA - GAMG [nTPM]":"1305.6","Cell RNA - HaCaT [nTPM]":"976.1","Cell RNA - HAP1 [nTPM]":"1499.0","Cell RNA - HBEC3-KT [nTPM]":"2195.3","Cell RNA - HBF TERT88 [nTPM]":"1540.9","Cell RNA - HDLM-2 [nTPM]":"401.4","Cell RNA - HEK 293 [nTPM]":"784.6","Cell RNA - HEL [nTPM]":"984.9","Cell RNA - HeLa [nTPM]":"1651.7","Cell RNA - Hep G2 [nTPM]":"2232.7","Cell RNA - HHSteC [nTPM]":"1420.7","Cell RNA - HL-60 [nTPM]":"641.6","Cell RNA - HMC-1 [nTPM]":"483.0","Cell RNA - HSkMC [nTPM]":"1566.4","Cell RNA - hTCEpi [nTPM]":"1113.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"875.1","Cell RNA - hTERT-HME1 [nTPM]":"1399.1","Cell RNA - hTERT-RPE1 [nTPM]":"1561.0","Cell RNA - HUVEC TERT2 [nTPM]":"1669.7","Cell RNA - JURKAT [nTPM]":"1100.6","Cell RNA - K-562 [nTPM]":"692.0","Cell RNA - Karpas-707 [nTPM]":"1294.6","Cell RNA - LHCN-M2 [nTPM]":"1319.1","Cell RNA - MCF7 [nTPM]":"4131.0","Cell RNA - MOLT-4 [nTPM]":"1759.5","Cell RNA - NB-4 [nTPM]":"1452.8","Cell RNA - NTERA-2 [nTPM]":"487.9","Cell RNA - OE19 [nTPM]":"214.0","Cell RNA - PC-3 [nTPM]":"894.4","Cell RNA - REH [nTPM]":"1436.7","Cell RNA - RH-30 [nTPM]":"1287.3","Cell RNA - RPMI-8226 [nTPM]":"1589.4","Cell RNA - RPTEC TERT1 [nTPM]":"2165.5","Cell RNA - RT4 [nTPM]":"1315.8","Cell RNA - SCLC-21H [nTPM]":"1818.3","Cell RNA - SH-SY5Y [nTPM]":"3853.2","Cell RNA - SiHa [nTPM]":"2157.6","Cell RNA - SK-BR-3 [nTPM]":"2117.1","Cell RNA - SK-MEL-30 [nTPM]":"1354.2","Cell RNA - SuSa [nTPM]":"1921.8","Cell RNA - T-47d [nTPM]":"1570.0","Cell RNA - THP-1 [nTPM]":"1581.7","Cell RNA - TIME [nTPM]":"1343.3","Cell RNA - U-138 MG [nTPM]":"2210.2","Cell RNA - U-2 OS [nTPM]":"1477.0","Cell RNA - U-2197 [nTPM]":"688.5","Cell RNA - U-251 MG [nTPM]":"1452.3","Cell RNA - U-266\/70 [nTPM]":"1314.0","Cell RNA - U-266\/84 [nTPM]":"993.3","Cell RNA - U-698 [nTPM]":"1583.2","Cell RNA - U-87 MG [nTPM]":"900.0","Cell RNA - U-937 [nTPM]":"473.7","Cell RNA - WM-115 [nTPM]":"1107.1","Blood RNA - basophil [nTPM]":"217.9","Blood RNA - classical monocyte [nTPM]":"96.7","Blood RNA - eosinophil [nTPM]":"114.2","Blood RNA - gdT-cell [nTPM]":"68.9","Blood RNA - intermediate monocyte [nTPM]":"127.3","Blood RNA - MAIT T-cell [nTPM]":"80.0","Blood RNA - memory B-cell [nTPM]":"103.2","Blood RNA - memory CD4 T-cell [nTPM]":"73.4","Blood RNA - memory CD8 T-cell [nTPM]":"74.8","Blood RNA - myeloid DC [nTPM]":"129.2","Blood RNA - naive B-cell [nTPM]":"93.6","Blood RNA - naive CD4 T-cell [nTPM]":"65.8","Blood RNA - naive CD8 T-cell [nTPM]":"82.6","Blood RNA - neutrophil [nTPM]":"103.4","Blood RNA - NK-cell [nTPM]":"95.6","Blood RNA - non-classical monocyte [nTPM]":"150.3","Blood RNA - plasmacytoid DC [nTPM]":"174.9","Blood RNA - T-reg [nTPM]":"92.7","Blood RNA - total PBMC [nTPM]":"100.9","Brain RNA - amygdala [nTPM]":"1564.4","Brain RNA - basal ganglia [nTPM]":"1524.7","Brain RNA - cerebellum [nTPM]":"1413.1","Brain RNA - cerebral cortex [nTPM]":"1768.3","Brain RNA - hippocampal formation [nTPM]":"1557.3","Brain RNA - hypothalamus [nTPM]":"2716.9","Brain RNA - medulla oblongata [nTPM]":"1710.5","Brain RNA - midbrain [nTPM]":"1949.4","Brain RNA - pons [nTPM]":"1963.4","Brain RNA - spinal cord [nTPM]":"1598.4","Brain RNA - thalamus [nTPM]":"1882.0","Brain RNA - white matter [nTPM]":"1483.9","Single Cell Type RNA - Adipocytes [nTPM]":"982.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"221.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"258.8","Single Cell Type RNA - Astrocytes [nTPM]":"192.0","Single Cell Type RNA - B-cells [nTPM]":"310.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"130.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"182.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"130.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"205.5","Single Cell Type RNA - Bipolar cells [nTPM]":"397.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"465.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"684.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1025.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"237.4","Single Cell Type RNA - Club cells [nTPM]":"212.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"261.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"56.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"832.6","Single Cell Type RNA - dendritic cells [nTPM]":"390.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"357.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"444.1","Single Cell Type RNA - Ductal cells [nTPM]":"233.9","Single Cell Type RNA - Early spermatids [nTPM]":"734.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"487.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"515.7","Single Cell Type RNA - Endothelial cells [nTPM]":"518.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"463.1","Single Cell Type RNA - Erythroid cells [nTPM]":"252.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"232.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"228.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"342.0","Single Cell Type RNA - Fibroblasts [nTPM]":"380.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"196.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"685.0","Single Cell Type RNA - granulocytes [nTPM]":"138.6","Single Cell Type RNA - Granulosa cells [nTPM]":"542.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"380.1","Single Cell Type RNA - Hepatocytes [nTPM]":"256.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"379.1","Single Cell Type RNA - Horizontal cells [nTPM]":"1886.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"439.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"327.2","Single Cell Type RNA - Ionocytes [nTPM]":"181.0","Single Cell Type RNA - Kupffer cells [nTPM]":"380.4","Single Cell Type RNA - Langerhans cells [nTPM]":"405.7","Single Cell Type RNA - Late spermatids [nTPM]":"1756.9","Single Cell Type RNA - Leydig cells [nTPM]":"265.3","Single Cell Type RNA - Macrophages [nTPM]":"437.1","Single Cell Type RNA - Melanocytes [nTPM]":"222.3","Single Cell Type RNA - Microglial cells [nTPM]":"236.1","Single Cell Type RNA - monocytes [nTPM]":"204.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1367.2","Single Cell Type RNA - NK-cells [nTPM]":"137.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"194.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"166.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"339.9","Single Cell Type RNA - Paneth cells [nTPM]":"300.0","Single Cell Type RNA - Peritubular cells [nTPM]":"197.1","Single Cell Type RNA - Plasma cells [nTPM]":"309.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"268.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"273.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"153.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"218.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"222.0","Single Cell Type RNA - Sertoli cells [nTPM]":"210.4","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1998.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"560.4","Single Cell Type RNA - Spermatocytes [nTPM]":"226.0","Single Cell Type RNA - Spermatogonia [nTPM]":"73.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"240.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"117.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1211.7","Single Cell Type RNA - T-cells [nTPM]":"301.8","Single Cell Type RNA - Theca cells [nTPM]":"860.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"304.4","Single Cell Type RNA - Urothelial cells [nTPM]":"316.5"},{"Gene":"GNB1","Gene synonym":[],"Ensembl":"ENSG00000078369","Gene description":"G protein subunit beta 1","Uniprot":["P62873"],"Chromosome":"1","Position":"1785285-1891117","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins","Transporters"],"Biological process":null,"Molecular function":["Transducer"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"retina":"2629.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Rod photoreceptor cells":"1373.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040736"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1900000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA040736":"AB_2677106"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.61e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.47e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-2"},"Tissue RNA - adipose tissue [nTPM]":"178.1","Tissue RNA - adrenal gland [nTPM]":"123.8","Tissue RNA - amygdala [nTPM]":"167.9","Tissue RNA - appendix [nTPM]":"179.9","Tissue RNA - basal ganglia [nTPM]":"212.3","Tissue RNA - bone marrow [nTPM]":"147.6","Tissue RNA - breast [nTPM]":"119.7","Tissue RNA - cerebellum [nTPM]":"147.8","Tissue RNA - cerebral cortex [nTPM]":"234.4","Tissue RNA - cervix [nTPM]":"124.3","Tissue RNA - choroid plexus [nTPM]":"87.1","Tissue RNA - colon [nTPM]":"165.7","Tissue RNA - duodenum [nTPM]":"173.7","Tissue RNA - endometrium 1 [nTPM]":"127.1","Tissue RNA - epididymis [nTPM]":"90.8","Tissue RNA - esophagus [nTPM]":"126.7","Tissue RNA - fallopian tube [nTPM]":"114.4","Tissue RNA - gallbladder [nTPM]":"110.9","Tissue RNA - heart muscle [nTPM]":"119.6","Tissue RNA - hippocampal formation [nTPM]":"228.3","Tissue RNA - hypothalamus [nTPM]":"172.0","Tissue RNA - kidney [nTPM]":"125.1","Tissue RNA - liver [nTPM]":"103.3","Tissue RNA - lung [nTPM]":"146.7","Tissue RNA - lymph node [nTPM]":"160.0","Tissue RNA - medulla oblongata [nTPM]":"159.5","Tissue RNA - midbrain [nTPM]":"153.2","Tissue RNA - ovary [nTPM]":"130.2","Tissue RNA - pancreas [nTPM]":"105.9","Tissue RNA - parathyroid gland [nTPM]":"148.2","Tissue RNA - pituitary gland [nTPM]":"106.8","Tissue RNA - placenta [nTPM]":"141.1","Tissue RNA - pons [nTPM]":"169.5","Tissue RNA - prostate [nTPM]":"118.3","Tissue RNA - rectum [nTPM]":"123.1","Tissue RNA - retina [nTPM]":"2629.0","Tissue RNA - salivary gland [nTPM]":"120.6","Tissue RNA - seminal vesicle [nTPM]":"118.9","Tissue RNA - skeletal muscle [nTPM]":"66.8","Tissue RNA - skin 1 [nTPM]":"111.8","Tissue RNA - small intestine [nTPM]":"208.2","Tissue RNA - smooth muscle [nTPM]":"156.1","Tissue RNA - spinal cord [nTPM]":"131.6","Tissue RNA - spleen [nTPM]":"142.6","Tissue RNA - stomach 1 [nTPM]":"129.7","Tissue RNA - testis [nTPM]":"99.0","Tissue RNA - thalamus [nTPM]":"168.9","Tissue RNA - thymus [nTPM]":"167.3","Tissue RNA - thyroid gland [nTPM]":"113.6","Tissue RNA - tongue [nTPM]":"97.1","Tissue RNA - tonsil [nTPM]":"145.6","Tissue RNA - urinary bladder [nTPM]":"152.6","Tissue RNA - vagina [nTPM]":"102.7","Tissue RNA - white matter [nTPM]":"203.9","Cell RNA - A-431 [nTPM]":"373.2","Cell RNA - A549 [nTPM]":"344.2","Cell RNA - AF22 [nTPM]":"400.2","Cell RNA - AN3-CA [nTPM]":"280.4","Cell RNA - ASC diff [nTPM]":"222.4","Cell RNA - ASC TERT1 [nTPM]":"242.4","Cell RNA - BEWO [nTPM]":"154.4","Cell RNA - BJ [nTPM]":"515.4","Cell RNA - BJ hTERT+ [nTPM]":"339.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"456.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"355.2","Cell RNA - CACO-2 [nTPM]":"282.8","Cell RNA - CAPAN-2 [nTPM]":"361.8","Cell RNA - Daudi [nTPM]":"385.5","Cell RNA - EFO-21 [nTPM]":"369.3","Cell RNA - fHDF\/TERT166 [nTPM]":"522.5","Cell RNA - GAMG [nTPM]":"258.6","Cell RNA - HaCaT [nTPM]":"192.0","Cell RNA - HAP1 [nTPM]":"405.5","Cell RNA - HBEC3-KT [nTPM]":"373.5","Cell RNA - HBF TERT88 [nTPM]":"411.4","Cell RNA - HDLM-2 [nTPM]":"595.9","Cell RNA - HEK 293 [nTPM]":"199.2","Cell RNA - HEL [nTPM]":"375.0","Cell RNA - HeLa [nTPM]":"308.2","Cell RNA - Hep G2 [nTPM]":"325.6","Cell RNA - HHSteC [nTPM]":"279.1","Cell RNA - HL-60 [nTPM]":"227.7","Cell RNA - HMC-1 [nTPM]":"394.4","Cell RNA - HSkMC [nTPM]":"216.4","Cell RNA - hTCEpi [nTPM]":"256.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"437.2","Cell RNA - hTERT-HME1 [nTPM]":"402.9","Cell RNA - hTERT-RPE1 [nTPM]":"306.1","Cell RNA - HUVEC TERT2 [nTPM]":"376.8","Cell RNA - JURKAT [nTPM]":"298.8","Cell RNA - K-562 [nTPM]":"236.8","Cell RNA - Karpas-707 [nTPM]":"337.8","Cell RNA - LHCN-M2 [nTPM]":"440.0","Cell RNA - MCF7 [nTPM]":"230.3","Cell RNA - MOLT-4 [nTPM]":"501.9","Cell RNA - NB-4 [nTPM]":"177.4","Cell RNA - NTERA-2 [nTPM]":"230.8","Cell RNA - OE19 [nTPM]":"190.0","Cell RNA - PC-3 [nTPM]":"275.0","Cell RNA - REH [nTPM]":"482.9","Cell RNA - RH-30 [nTPM]":"308.7","Cell RNA - RPMI-8226 [nTPM]":"306.4","Cell RNA - RPTEC TERT1 [nTPM]":"310.8","Cell RNA - RT4 [nTPM]":"227.5","Cell RNA - SCLC-21H [nTPM]":"489.9","Cell RNA - SH-SY5Y [nTPM]":"556.5","Cell RNA - SiHa [nTPM]":"477.1","Cell RNA - SK-BR-3 [nTPM]":"306.6","Cell RNA - SK-MEL-30 [nTPM]":"420.5","Cell RNA - SuSa [nTPM]":"272.8","Cell RNA - T-47d [nTPM]":"214.8","Cell RNA - THP-1 [nTPM]":"305.9","Cell RNA - TIME [nTPM]":"579.4","Cell RNA - U-138 MG [nTPM]":"399.3","Cell RNA - U-2 OS [nTPM]":"267.5","Cell RNA - U-2197 [nTPM]":"314.8","Cell RNA - U-251 MG [nTPM]":"379.1","Cell RNA - U-266\/70 [nTPM]":"227.1","Cell RNA - U-266\/84 [nTPM]":"432.8","Cell RNA - U-698 [nTPM]":"888.7","Cell RNA - U-87 MG [nTPM]":"341.4","Cell RNA - U-937 [nTPM]":"470.1","Cell RNA - WM-115 [nTPM]":"230.5","Blood RNA - basophil [nTPM]":"11.4","Blood RNA - classical monocyte [nTPM]":"13.3","Blood RNA - eosinophil [nTPM]":"21.9","Blood RNA - gdT-cell [nTPM]":"9.9","Blood RNA - intermediate monocyte [nTPM]":"16.4","Blood RNA - MAIT T-cell [nTPM]":"9.1","Blood RNA - memory B-cell [nTPM]":"9.0","Blood RNA - memory CD4 T-cell [nTPM]":"9.9","Blood RNA - memory CD8 T-cell [nTPM]":"11.2","Blood RNA - myeloid DC [nTPM]":"13.3","Blood RNA - naive B-cell [nTPM]":"9.6","Blood RNA - naive CD4 T-cell [nTPM]":"6.7","Blood RNA - naive CD8 T-cell [nTPM]":"7.2","Blood RNA - neutrophil [nTPM]":"22.1","Blood RNA - NK-cell [nTPM]":"12.8","Blood RNA - non-classical monocyte [nTPM]":"17.5","Blood RNA - plasmacytoid DC [nTPM]":"22.7","Blood RNA - T-reg [nTPM]":"12.5","Blood RNA - total PBMC [nTPM]":"8.2","Brain RNA - amygdala [nTPM]":"167.9","Brain RNA - basal ganglia [nTPM]":"212.3","Brain RNA - cerebellum [nTPM]":"147.8","Brain RNA - cerebral cortex [nTPM]":"234.4","Brain RNA - hippocampal formation [nTPM]":"228.3","Brain RNA - hypothalamus [nTPM]":"172.0","Brain RNA - medulla oblongata [nTPM]":"159.5","Brain RNA - midbrain [nTPM]":"153.2","Brain RNA - pons [nTPM]":"169.5","Brain RNA - spinal cord [nTPM]":"131.6","Brain RNA - thalamus [nTPM]":"168.9","Brain RNA - white matter [nTPM]":"203.9","Single Cell Type RNA - Adipocytes [nTPM]":"172.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"70.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"42.6","Single Cell Type RNA - Astrocytes [nTPM]":"57.5","Single Cell Type RNA - B-cells [nTPM]":"67.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"86.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"51.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"47.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"33.0","Single Cell Type RNA - Bipolar cells [nTPM]":"149.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"65.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"57.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"60.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"52.9","Single Cell Type RNA - Club cells [nTPM]":"42.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"75.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"175.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"44.2","Single Cell Type RNA - dendritic cells [nTPM]":"124.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"140.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"46.9","Single Cell Type RNA - Ductal cells [nTPM]":"88.0","Single Cell Type RNA - Early spermatids [nTPM]":"29.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"93.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"112.9","Single Cell Type RNA - Endothelial cells [nTPM]":"131.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"122.9","Single Cell Type RNA - Erythroid cells [nTPM]":"40.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"102.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"100.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"99.4","Single Cell Type RNA - Fibroblasts [nTPM]":"77.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"52.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"121.6","Single Cell Type RNA - granulocytes [nTPM]":"53.8","Single Cell Type RNA - Granulosa cells [nTPM]":"101.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"95.3","Single Cell Type RNA - Hepatocytes [nTPM]":"60.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"100.8","Single Cell Type RNA - Horizontal cells [nTPM]":"180.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"101.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"95.5","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"152.7","Single Cell Type RNA - Langerhans cells [nTPM]":"114.6","Single Cell Type RNA - Late spermatids [nTPM]":"33.8","Single Cell Type RNA - Leydig cells [nTPM]":"76.1","Single Cell Type RNA - Macrophages [nTPM]":"128.0","Single Cell Type RNA - Melanocytes [nTPM]":"53.4","Single Cell Type RNA - Microglial cells [nTPM]":"115.2","Single Cell Type RNA - monocytes [nTPM]":"119.5","Single Cell Type RNA - Muller glia cells [nTPM]":"250.3","Single Cell Type RNA - NK-cells [nTPM]":"73.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"70.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"110.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"175.4","Single Cell Type RNA - Paneth cells [nTPM]":"91.0","Single Cell Type RNA - Peritubular cells [nTPM]":"88.0","Single Cell Type RNA - Plasma cells [nTPM]":"75.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"100.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"167.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"67.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"41.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1373.7","Single Cell Type RNA - Sertoli cells [nTPM]":"78.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"71.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"105.9","Single Cell Type RNA - Spermatocytes [nTPM]":"68.8","Single Cell Type RNA - Spermatogonia [nTPM]":"67.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"51.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"101.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"36.4","Single Cell Type RNA - T-cells [nTPM]":"74.5","Single Cell Type RNA - Theca cells [nTPM]":"83.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"83.0","Single Cell Type RNA - Urothelial cells [nTPM]":"94.1"},{"Gene":"GNE","Gene synonym":["IBM2","Uae1"],"Ensembl":"ENSG00000159921","Gene description":"Glucosamine (UDP-N-acetyl)-2-epimerase\/N-acetylmannosamine kinase","Uniprot":["Q9Y223"],"Chromosome":"9","Position":"36214441-36277042","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Allosteric enzyme","Hydrolase","Kinase","Multifunctional enzyme","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"intestine":"48.4","liver":"90.5","salivary gland":"55.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"59.3","Hepatocytes":"119.3","Intestinal goblet cells":"88.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RPTEC TERT1":"107.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007045","HPA027258"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 27: Mucus-secreting cells - Mucin production","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA007045":"AB_1079003","HPA027258":"AB_1849873"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.28e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.9","Tissue RNA - adrenal gland [nTPM]":"9.0","Tissue RNA - amygdala [nTPM]":"5.5","Tissue RNA - appendix [nTPM]":"8.7","Tissue RNA - basal ganglia [nTPM]":"7.4","Tissue RNA - bone marrow [nTPM]":"15.5","Tissue RNA - breast [nTPM]":"15.8","Tissue RNA - cerebellum [nTPM]":"8.9","Tissue RNA - cerebral cortex [nTPM]":"6.5","Tissue RNA - cervix [nTPM]":"11.3","Tissue RNA - choroid plexus [nTPM]":"7.9","Tissue RNA - colon [nTPM]":"34.0","Tissue RNA - duodenum [nTPM]":"4.3","Tissue RNA - endometrium 1 [nTPM]":"10.3","Tissue RNA - epididymis [nTPM]":"3.5","Tissue RNA - esophagus [nTPM]":"11.6","Tissue RNA - fallopian tube [nTPM]":"9.1","Tissue RNA - gallbladder [nTPM]":"7.4","Tissue RNA - heart muscle [nTPM]":"7.7","Tissue RNA - hippocampal formation [nTPM]":"5.5","Tissue RNA - hypothalamus [nTPM]":"7.3","Tissue RNA - kidney [nTPM]":"10.0","Tissue RNA - liver [nTPM]":"90.5","Tissue RNA - lung [nTPM]":"6.8","Tissue RNA - lymph node [nTPM]":"7.3","Tissue RNA - medulla oblongata [nTPM]":"7.7","Tissue RNA - midbrain [nTPM]":"7.3","Tissue RNA - ovary [nTPM]":"14.8","Tissue RNA - pancreas [nTPM]":"10.2","Tissue RNA - parathyroid gland [nTPM]":"6.1","Tissue RNA - pituitary gland [nTPM]":"4.8","Tissue RNA - placenta [nTPM]":"14.2","Tissue RNA - pons [nTPM]":"8.9","Tissue RNA - prostate [nTPM]":"15.3","Tissue RNA - rectum [nTPM]":"48.4","Tissue RNA - retina [nTPM]":"8.0","Tissue RNA - salivary gland [nTPM]":"55.3","Tissue RNA - seminal vesicle [nTPM]":"7.2","Tissue RNA - skeletal muscle [nTPM]":"7.9","Tissue RNA - skin 1 [nTPM]":"3.8","Tissue RNA - small intestine [nTPM]":"7.6","Tissue RNA - smooth muscle [nTPM]":"11.7","Tissue RNA - spinal cord [nTPM]":"6.6","Tissue RNA - spleen [nTPM]":"6.2","Tissue RNA - stomach 1 [nTPM]":"4.6","Tissue RNA - testis [nTPM]":"4.8","Tissue RNA - thalamus [nTPM]":"7.1","Tissue RNA - thymus [nTPM]":"6.2","Tissue RNA - thyroid gland [nTPM]":"6.9","Tissue RNA - tongue [nTPM]":"15.3","Tissue RNA - tonsil [nTPM]":"9.5","Tissue RNA - urinary bladder [nTPM]":"14.2","Tissue RNA - vagina [nTPM]":"7.5","Tissue RNA - white matter [nTPM]":"10.5","Cell RNA - A-431 [nTPM]":"9.9","Cell RNA - A549 [nTPM]":"44.4","Cell RNA - AF22 [nTPM]":"20.1","Cell RNA - AN3-CA [nTPM]":"17.1","Cell RNA - ASC diff [nTPM]":"22.5","Cell RNA - ASC TERT1 [nTPM]":"22.4","Cell RNA - BEWO [nTPM]":"29.9","Cell RNA - BJ [nTPM]":"13.5","Cell RNA - BJ hTERT+ [nTPM]":"17.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"25.1","Cell RNA - CACO-2 [nTPM]":"10.5","Cell RNA - CAPAN-2 [nTPM]":"32.6","Cell RNA - Daudi [nTPM]":"13.5","Cell RNA - EFO-21 [nTPM]":"14.2","Cell RNA - fHDF\/TERT166 [nTPM]":"24.2","Cell RNA - GAMG [nTPM]":"50.5","Cell RNA - HaCaT [nTPM]":"3.9","Cell RNA - HAP1 [nTPM]":"15.3","Cell RNA - HBEC3-KT [nTPM]":"4.6","Cell RNA - HBF TERT88 [nTPM]":"21.8","Cell RNA - HDLM-2 [nTPM]":"25.1","Cell RNA - HEK 293 [nTPM]":"1.4","Cell RNA - HEL [nTPM]":"11.0","Cell RNA - HeLa [nTPM]":"26.0","Cell RNA - Hep G2 [nTPM]":"15.2","Cell RNA - HHSteC [nTPM]":"15.4","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"31.2","Cell RNA - HSkMC [nTPM]":"14.4","Cell RNA - hTCEpi [nTPM]":"4.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.0","Cell RNA - hTERT-HME1 [nTPM]":"30.6","Cell RNA - hTERT-RPE1 [nTPM]":"14.3","Cell RNA - HUVEC TERT2 [nTPM]":"8.4","Cell RNA - JURKAT [nTPM]":"20.7","Cell RNA - K-562 [nTPM]":"14.4","Cell RNA - Karpas-707 [nTPM]":"27.3","Cell RNA - LHCN-M2 [nTPM]":"19.3","Cell RNA - MCF7 [nTPM]":"1.8","Cell RNA - MOLT-4 [nTPM]":"19.1","Cell RNA - NB-4 [nTPM]":"6.3","Cell RNA - NTERA-2 [nTPM]":"11.8","Cell RNA - OE19 [nTPM]":"6.7","Cell RNA - PC-3 [nTPM]":"23.7","Cell RNA - REH [nTPM]":"15.5","Cell RNA - RH-30 [nTPM]":"16.3","Cell RNA - RPMI-8226 [nTPM]":"3.8","Cell RNA - RPTEC TERT1 [nTPM]":"107.7","Cell RNA - RT4 [nTPM]":"19.4","Cell RNA - SCLC-21H [nTPM]":"16.7","Cell RNA - SH-SY5Y [nTPM]":"15.2","Cell RNA - SiHa [nTPM]":"13.7","Cell RNA - SK-BR-3 [nTPM]":"5.3","Cell RNA - SK-MEL-30 [nTPM]":"12.6","Cell RNA - SuSa [nTPM]":"7.1","Cell RNA - T-47d [nTPM]":"4.8","Cell RNA - THP-1 [nTPM]":"12.0","Cell RNA - TIME [nTPM]":"12.2","Cell RNA - U-138 MG [nTPM]":"12.7","Cell RNA - U-2 OS [nTPM]":"12.9","Cell RNA - U-2197 [nTPM]":"15.5","Cell RNA - U-251 MG [nTPM]":"12.2","Cell RNA - U-266\/70 [nTPM]":"11.7","Cell RNA - U-266\/84 [nTPM]":"26.0","Cell RNA - U-698 [nTPM]":"7.0","Cell RNA - U-87 MG [nTPM]":"17.0","Cell RNA - U-937 [nTPM]":"9.8","Cell RNA - WM-115 [nTPM]":"18.2","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"0.9","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.2","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"0.8","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"5.5","Brain RNA - basal ganglia [nTPM]":"7.4","Brain RNA - cerebellum [nTPM]":"8.9","Brain RNA - cerebral cortex [nTPM]":"6.5","Brain RNA - hippocampal formation [nTPM]":"5.5","Brain RNA - hypothalamus [nTPM]":"7.3","Brain RNA - medulla oblongata [nTPM]":"7.7","Brain RNA - midbrain [nTPM]":"7.3","Brain RNA - pons [nTPM]":"8.9","Brain RNA - spinal cord [nTPM]":"6.6","Brain RNA - thalamus [nTPM]":"7.1","Brain RNA - white matter [nTPM]":"10.5","Single Cell Type RNA - Adipocytes [nTPM]":"9.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.0","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"7.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"8.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"16.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.6","Single Cell Type RNA - dendritic cells [nTPM]":"4.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"59.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"10.4","Single Cell Type RNA - Early spermatids [nTPM]":"3.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.1","Single Cell Type RNA - Endothelial cells [nTPM]":"6.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.5","Single Cell Type RNA - Erythroid cells [nTPM]":"7.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.5","Single Cell Type RNA - Fibroblasts [nTPM]":"8.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.6","Single Cell Type RNA - granulocytes [nTPM]":"10.1","Single Cell Type RNA - Granulosa cells [nTPM]":"9.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.1","Single Cell Type RNA - Hepatocytes [nTPM]":"119.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.9","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"88.1","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"7.8","Single Cell Type RNA - Langerhans cells [nTPM]":"4.4","Single Cell Type RNA - Late spermatids [nTPM]":"2.4","Single Cell Type RNA - Leydig cells [nTPM]":"10.8","Single Cell Type RNA - Macrophages [nTPM]":"5.4","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"6.1","Single Cell Type RNA - Muller glia cells [nTPM]":"1.9","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"32.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"28.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.3","Single Cell Type RNA - Paneth cells [nTPM]":"20.3","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"7.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.9","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.8","Single Cell Type RNA - Spermatogonia [nTPM]":"2.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"19.8","Single Cell Type RNA - T-cells [nTPM]":"5.7","Single Cell Type RNA - Theca cells [nTPM]":"2.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.8","Single Cell Type RNA - Urothelial cells [nTPM]":"13.4"},{"Gene":"GNMT","Gene synonym":[],"Ensembl":"ENSG00000124713","Gene description":"Glycine N-methyltransferase","Uniprot":["Q14749"],"Chromosome":"6","Position":"42960754-42963880","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"liver":"296.5","pancreas":"600.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Hepatocytes":"842.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"20","RNA cancer specific FPKM":{"liver cancer":"69.6","prostate cancer":"49.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"8.5","SCLC-21H":"9.5","T-47d":"6.1"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"cerebellum":"15.7"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027501"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"390000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA027501":"AB_1849879"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.86e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-6"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.9","Tissue RNA - adrenal gland [nTPM]":"0.9","Tissue RNA - amygdala [nTPM]":"2.3","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"3.8","Tissue RNA - breast [nTPM]":"7.1","Tissue RNA - cerebellum [nTPM]":"2.8","Tissue RNA - cerebral cortex [nTPM]":"2.4","Tissue RNA - cervix [nTPM]":"0.8","Tissue RNA - choroid plexus [nTPM]":"2.0","Tissue RNA - colon [nTPM]":"0.7","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.8","Tissue RNA - epididymis [nTPM]":"2.2","Tissue RNA - esophagus [nTPM]":"0.6","Tissue RNA - fallopian tube [nTPM]":"1.3","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"4.7","Tissue RNA - hippocampal formation [nTPM]":"2.2","Tissue RNA - hypothalamus [nTPM]":"2.2","Tissue RNA - kidney [nTPM]":"0.9","Tissue RNA - liver [nTPM]":"296.5","Tissue RNA - lung [nTPM]":"2.0","Tissue RNA - lymph node [nTPM]":"1.0","Tissue RNA - medulla oblongata [nTPM]":"1.1","Tissue RNA - midbrain [nTPM]":"1.0","Tissue RNA - ovary [nTPM]":"1.9","Tissue RNA - pancreas [nTPM]":"600.1","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"8.4","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"1.1","Tissue RNA - prostate [nTPM]":"20.3","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"2.2","Tissue RNA - salivary gland [nTPM]":"9.8","Tissue RNA - seminal vesicle [nTPM]":"1.2","Tissue RNA - skeletal muscle [nTPM]":"1.8","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"1.6","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"2.9","Tissue RNA - stomach 1 [nTPM]":"50.8","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"1.9","Tissue RNA - thymus [nTPM]":"1.8","Tissue RNA - thyroid gland [nTPM]":"1.9","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"1.2","Tissue RNA - urinary bladder [nTPM]":"0.8","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"2.1","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"1.4","Cell RNA - AN3-CA [nTPM]":"3.9","Cell RNA - ASC diff [nTPM]":"0.4","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"1.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.9","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"1.3","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.3","Cell RNA - GAMG [nTPM]":"0.7","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"1.6","Cell RNA - HEK 293 [nTPM]":"1.2","Cell RNA - HEL [nTPM]":"1.0","Cell RNA - HeLa [nTPM]":"0.9","Cell RNA - Hep G2 [nTPM]":"8.5","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.9","Cell RNA - HMC-1 [nTPM]":"1.8","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.3","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"3.0","Cell RNA - K-562 [nTPM]":"1.2","Cell RNA - Karpas-707 [nTPM]":"1.5","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"1.8","Cell RNA - MOLT-4 [nTPM]":"1.6","Cell RNA - NB-4 [nTPM]":"3.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.4","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"1.4","Cell RNA - RH-30 [nTPM]":"1.3","Cell RNA - RPMI-8226 [nTPM]":"0.8","Cell RNA - RPTEC TERT1 [nTPM]":"0.6","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"9.5","Cell RNA - SH-SY5Y [nTPM]":"1.3","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"1.3","Cell RNA - SK-MEL-30 [nTPM]":"0.6","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"6.1","Cell RNA - THP-1 [nTPM]":"2.8","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.7","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.8","Cell RNA - U-266\/70 [nTPM]":"1.0","Cell RNA - U-266\/84 [nTPM]":"1.0","Cell RNA - U-698 [nTPM]":"1.1","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"1.6","Cell RNA - WM-115 [nTPM]":"0.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"2.3","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"2.8","Brain RNA - cerebral cortex [nTPM]":"2.4","Brain RNA - hippocampal formation [nTPM]":"2.2","Brain RNA - hypothalamus [nTPM]":"2.2","Brain RNA - medulla oblongata [nTPM]":"1.1","Brain RNA - midbrain [nTPM]":"1.0","Brain RNA - pons [nTPM]":"1.1","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"1.9","Brain RNA - white matter [nTPM]":"2.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.2","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"2.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"1.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"2.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"77.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"24.3","Single Cell Type RNA - Hepatocytes [nTPM]":"842.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.7","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"28.9","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"1.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"0.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"0.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"3.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"1.9"},{"Gene":"GNPAT","Gene synonym":["DAP-AT","DAPAT","DHAPAT"],"Ensembl":"ENSG00000116906","Gene description":"Glyceronephosphate O-acyltransferase","Uniprot":["O15228"],"Chromosome":"1","Position":"231241207-231277973","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Cataract","Disease variant","Dwarfism","Rhizomelic chondrodysplasia punctata"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"119.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.29e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Tissue RNA - adipose tissue [nTPM]":"22.4","Tissue RNA - adrenal gland [nTPM]":"26.9","Tissue RNA - amygdala [nTPM]":"21.6","Tissue RNA - appendix [nTPM]":"20.5","Tissue RNA - basal ganglia [nTPM]":"24.0","Tissue RNA - bone marrow [nTPM]":"17.3","Tissue RNA - breast [nTPM]":"21.7","Tissue RNA - cerebellum [nTPM]":"23.9","Tissue RNA - cerebral cortex [nTPM]":"28.2","Tissue RNA - cervix [nTPM]":"18.3","Tissue RNA - choroid plexus [nTPM]":"25.2","Tissue RNA - colon [nTPM]":"30.0","Tissue RNA - duodenum [nTPM]":"30.0","Tissue RNA - endometrium 1 [nTPM]":"20.3","Tissue RNA - epididymis [nTPM]":"23.7","Tissue RNA - esophagus [nTPM]":"22.1","Tissue RNA - fallopian tube [nTPM]":"27.9","Tissue RNA - gallbladder [nTPM]":"18.2","Tissue RNA - heart muscle [nTPM]":"44.9","Tissue RNA - hippocampal formation [nTPM]":"22.0","Tissue RNA - hypothalamus [nTPM]":"23.5","Tissue RNA - kidney [nTPM]":"25.7","Tissue RNA - liver [nTPM]":"30.9","Tissue RNA - lung [nTPM]":"18.7","Tissue RNA - lymph node [nTPM]":"23.6","Tissue RNA - medulla oblongata [nTPM]":"24.1","Tissue RNA - midbrain [nTPM]":"22.5","Tissue RNA - ovary [nTPM]":"22.5","Tissue RNA - pancreas [nTPM]":"29.5","Tissue RNA - parathyroid gland [nTPM]":"22.6","Tissue RNA - pituitary gland [nTPM]":"17.9","Tissue RNA - placenta [nTPM]":"19.4","Tissue RNA - pons [nTPM]":"23.3","Tissue RNA - prostate [nTPM]":"22.8","Tissue RNA - rectum [nTPM]":"24.8","Tissue RNA - retina [nTPM]":"17.0","Tissue RNA - salivary gland [nTPM]":"26.4","Tissue RNA - seminal vesicle [nTPM]":"20.9","Tissue RNA - skeletal muscle [nTPM]":"101.9","Tissue RNA - skin 1 [nTPM]":"23.6","Tissue RNA - small intestine [nTPM]":"28.1","Tissue RNA - smooth muscle [nTPM]":"26.4","Tissue RNA - spinal cord [nTPM]":"23.6","Tissue RNA - spleen [nTPM]":"18.5","Tissue RNA - stomach 1 [nTPM]":"26.9","Tissue RNA - testis [nTPM]":"32.0","Tissue RNA - thalamus [nTPM]":"23.2","Tissue RNA - thymus [nTPM]":"27.5","Tissue RNA - thyroid gland [nTPM]":"20.8","Tissue RNA - tongue [nTPM]":"84.1","Tissue RNA - tonsil [nTPM]":"25.8","Tissue RNA - urinary bladder [nTPM]":"21.5","Tissue RNA - vagina [nTPM]":"17.0","Tissue RNA - white matter [nTPM]":"26.1","Cell RNA - A-431 [nTPM]":"39.8","Cell RNA - A549 [nTPM]":"43.6","Cell RNA - AF22 [nTPM]":"60.4","Cell RNA - AN3-CA [nTPM]":"46.1","Cell RNA - ASC diff [nTPM]":"48.7","Cell RNA - ASC TERT1 [nTPM]":"71.4","Cell RNA - BEWO [nTPM]":"40.7","Cell RNA - BJ [nTPM]":"32.9","Cell RNA - BJ hTERT+ [nTPM]":"37.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"34.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"39.1","Cell RNA - CACO-2 [nTPM]":"56.1","Cell RNA - CAPAN-2 [nTPM]":"48.3","Cell RNA - Daudi [nTPM]":"57.0","Cell RNA - EFO-21 [nTPM]":"40.4","Cell RNA - fHDF\/TERT166 [nTPM]":"49.5","Cell RNA - GAMG [nTPM]":"35.9","Cell RNA - HaCaT [nTPM]":"41.9","Cell RNA - HAP1 [nTPM]":"40.6","Cell RNA - HBEC3-KT [nTPM]":"44.7","Cell RNA - HBF TERT88 [nTPM]":"50.0","Cell RNA - HDLM-2 [nTPM]":"64.8","Cell RNA - HEK 293 [nTPM]":"37.2","Cell RNA - HEL [nTPM]":"41.2","Cell RNA - HeLa [nTPM]":"41.4","Cell RNA - Hep G2 [nTPM]":"81.7","Cell RNA - HHSteC [nTPM]":"49.4","Cell RNA - HL-60 [nTPM]":"70.9","Cell RNA - HMC-1 [nTPM]":"31.4","Cell RNA - HSkMC [nTPM]":"50.1","Cell RNA - hTCEpi [nTPM]":"53.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"35.5","Cell RNA - hTERT-HME1 [nTPM]":"39.6","Cell RNA - hTERT-RPE1 [nTPM]":"44.5","Cell RNA - HUVEC TERT2 [nTPM]":"81.2","Cell RNA - JURKAT [nTPM]":"56.0","Cell RNA - K-562 [nTPM]":"61.1","Cell RNA - Karpas-707 [nTPM]":"53.3","Cell RNA - LHCN-M2 [nTPM]":"71.7","Cell RNA - MCF7 [nTPM]":"13.1","Cell RNA - MOLT-4 [nTPM]":"63.6","Cell RNA - NB-4 [nTPM]":"41.0","Cell RNA - NTERA-2 [nTPM]":"97.1","Cell RNA - OE19 [nTPM]":"112.0","Cell RNA - PC-3 [nTPM]":"49.5","Cell RNA - REH [nTPM]":"68.7","Cell RNA - RH-30 [nTPM]":"81.0","Cell RNA - RPMI-8226 [nTPM]":"66.9","Cell RNA - RPTEC TERT1 [nTPM]":"42.7","Cell RNA - RT4 [nTPM]":"29.2","Cell RNA - SCLC-21H [nTPM]":"40.0","Cell RNA - SH-SY5Y [nTPM]":"57.1","Cell RNA - SiHa [nTPM]":"55.2","Cell RNA - SK-BR-3 [nTPM]":"30.7","Cell RNA - SK-MEL-30 [nTPM]":"49.1","Cell RNA - SuSa [nTPM]":"23.8","Cell RNA - T-47d [nTPM]":"53.7","Cell RNA - THP-1 [nTPM]":"110.7","Cell RNA - TIME [nTPM]":"42.8","Cell RNA - U-138 MG [nTPM]":"34.5","Cell RNA - U-2 OS [nTPM]":"32.1","Cell RNA - U-2197 [nTPM]":"50.5","Cell RNA - U-251 MG [nTPM]":"83.3","Cell RNA - U-266\/70 [nTPM]":"68.2","Cell RNA - U-266\/84 [nTPM]":"93.6","Cell RNA - U-698 [nTPM]":"65.1","Cell RNA - U-87 MG [nTPM]":"49.8","Cell RNA - U-937 [nTPM]":"58.8","Cell RNA - WM-115 [nTPM]":"65.3","Blood RNA - basophil [nTPM]":"34.1","Blood RNA - classical monocyte [nTPM]":"36.4","Blood RNA - eosinophil [nTPM]":"37.3","Blood RNA - gdT-cell [nTPM]":"23.7","Blood RNA - intermediate monocyte [nTPM]":"37.1","Blood RNA - MAIT T-cell [nTPM]":"27.2","Blood RNA - memory B-cell [nTPM]":"35.1","Blood RNA - memory CD4 T-cell [nTPM]":"30.6","Blood RNA - memory CD8 T-cell [nTPM]":"31.3","Blood RNA - myeloid DC [nTPM]":"36.4","Blood RNA - naive B-cell [nTPM]":"37.7","Blood RNA - naive CD4 T-cell [nTPM]":"26.4","Blood RNA - naive CD8 T-cell [nTPM]":"24.4","Blood RNA - neutrophil [nTPM]":"14.3","Blood RNA - NK-cell [nTPM]":"26.9","Blood RNA - non-classical monocyte [nTPM]":"50.3","Blood RNA - plasmacytoid DC [nTPM]":"17.2","Blood RNA - T-reg [nTPM]":"37.9","Blood RNA - total PBMC [nTPM]":"29.8","Brain RNA - amygdala [nTPM]":"21.6","Brain RNA - basal ganglia [nTPM]":"24.0","Brain RNA - cerebellum [nTPM]":"23.9","Brain RNA - cerebral cortex [nTPM]":"28.2","Brain RNA - hippocampal formation [nTPM]":"22.0","Brain RNA - hypothalamus [nTPM]":"23.5","Brain RNA - medulla oblongata [nTPM]":"24.1","Brain RNA - midbrain [nTPM]":"22.5","Brain RNA - pons [nTPM]":"23.3","Brain RNA - spinal cord [nTPM]":"23.6","Brain RNA - thalamus [nTPM]":"23.2","Brain RNA - white matter [nTPM]":"26.1","Single Cell Type RNA - Adipocytes [nTPM]":"17.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.8","Single Cell Type RNA - Astrocytes [nTPM]":"19.9","Single Cell Type RNA - B-cells [nTPM]":"32.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"19.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"23.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"16.5","Single Cell Type RNA - Bipolar cells [nTPM]":"23.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"55.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"21.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.3","Single Cell Type RNA - dendritic cells [nTPM]":"20.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"41.5","Single Cell Type RNA - Early spermatids [nTPM]":"70.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"21.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.4","Single Cell Type RNA - Endothelial cells [nTPM]":"21.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"28.2","Single Cell Type RNA - Erythroid cells [nTPM]":"13.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"43.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.2","Single Cell Type RNA - Fibroblasts [nTPM]":"19.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.1","Single Cell Type RNA - granulocytes [nTPM]":"11.4","Single Cell Type RNA - Granulosa cells [nTPM]":"30.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.2","Single Cell Type RNA - Hepatocytes [nTPM]":"26.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"27.4","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.0","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"24.8","Single Cell Type RNA - Langerhans cells [nTPM]":"18.3","Single Cell Type RNA - Late spermatids [nTPM]":"119.2","Single Cell Type RNA - Leydig cells [nTPM]":"25.4","Single Cell Type RNA - Macrophages [nTPM]":"21.8","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"38.7","Single Cell Type RNA - Muller glia cells [nTPM]":"22.7","Single Cell Type RNA - NK-cells [nTPM]":"26.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"29.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"40.2","Single Cell Type RNA - Paneth cells [nTPM]":"30.3","Single Cell Type RNA - Peritubular cells [nTPM]":"26.7","Single Cell Type RNA - Plasma cells [nTPM]":"30.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"24.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"41.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"28.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"30.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.2","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.4","Single Cell Type RNA - Spermatocytes [nTPM]":"50.9","Single Cell Type RNA - Spermatogonia [nTPM]":"31.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.4","Single Cell Type RNA - T-cells [nTPM]":"24.5","Single Cell Type RNA - Theca cells [nTPM]":"19.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"30.1","Single Cell Type RNA - Urothelial cells [nTPM]":"19.0"},{"Gene":"GNPTAB","Gene synonym":["GNPTA","KIAA1208","MGC4170"],"Ensembl":"ENSG00000111670","Gene description":"N-acetylglucosamine-1-phosphate transferase subunits alpha and beta","Uniprot":["Q3T906"],"Chromosome":"12","Position":"101745499-101830959","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Mucolipidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"192.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014558","HPA042343"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"160000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA014558":"AB_2732409","HPA042343":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.71e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.48e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.9","Tissue RNA - adrenal gland [nTPM]":"7.9","Tissue RNA - amygdala [nTPM]":"18.8","Tissue RNA - appendix [nTPM]":"16.2","Tissue RNA - basal ganglia [nTPM]":"22.2","Tissue RNA - bone marrow [nTPM]":"23.9","Tissue RNA - breast [nTPM]":"16.4","Tissue RNA - cerebellum [nTPM]":"14.4","Tissue RNA - cerebral cortex [nTPM]":"20.0","Tissue RNA - cervix [nTPM]":"17.4","Tissue RNA - choroid plexus [nTPM]":"2.7","Tissue RNA - colon [nTPM]":"29.6","Tissue RNA - duodenum [nTPM]":"14.2","Tissue RNA - endometrium 1 [nTPM]":"11.8","Tissue RNA - epididymis [nTPM]":"6.2","Tissue RNA - esophagus [nTPM]":"15.6","Tissue RNA - fallopian tube [nTPM]":"8.8","Tissue RNA - gallbladder [nTPM]":"14.8","Tissue RNA - heart muscle [nTPM]":"21.5","Tissue RNA - hippocampal formation [nTPM]":"22.7","Tissue RNA - hypothalamus [nTPM]":"10.8","Tissue RNA - kidney [nTPM]":"14.5","Tissue RNA - liver [nTPM]":"9.4","Tissue RNA - lung [nTPM]":"27.0","Tissue RNA - lymph node [nTPM]":"20.6","Tissue RNA - medulla oblongata [nTPM]":"8.5","Tissue RNA - midbrain [nTPM]":"11.1","Tissue RNA - ovary [nTPM]":"7.2","Tissue RNA - pancreas [nTPM]":"11.3","Tissue RNA - parathyroid gland [nTPM]":"23.0","Tissue RNA - pituitary gland [nTPM]":"8.4","Tissue RNA - placenta [nTPM]":"14.8","Tissue RNA - pons [nTPM]":"9.7","Tissue RNA - prostate [nTPM]":"20.1","Tissue RNA - rectum [nTPM]":"30.3","Tissue RNA - retina [nTPM]":"13.0","Tissue RNA - salivary gland [nTPM]":"54.3","Tissue RNA - seminal vesicle [nTPM]":"13.0","Tissue RNA - skeletal muscle [nTPM]":"16.4","Tissue RNA - skin 1 [nTPM]":"25.1","Tissue RNA - small intestine [nTPM]":"16.2","Tissue RNA - smooth muscle [nTPM]":"15.9","Tissue RNA - spinal cord [nTPM]":"8.9","Tissue RNA - spleen [nTPM]":"19.0","Tissue RNA - stomach 1 [nTPM]":"21.3","Tissue RNA - testis [nTPM]":"10.4","Tissue RNA - thalamus [nTPM]":"12.4","Tissue RNA - thymus [nTPM]":"34.1","Tissue RNA - thyroid gland [nTPM]":"13.9","Tissue RNA - tongue [nTPM]":"25.9","Tissue RNA - tonsil [nTPM]":"17.8","Tissue RNA - urinary bladder [nTPM]":"19.3","Tissue RNA - vagina [nTPM]":"12.0","Tissue RNA - white matter [nTPM]":"13.3","Cell RNA - A-431 [nTPM]":"18.2","Cell RNA - A549 [nTPM]":"17.5","Cell RNA - AF22 [nTPM]":"6.4","Cell RNA - AN3-CA [nTPM]":"10.9","Cell RNA - ASC diff [nTPM]":"52.3","Cell RNA - ASC TERT1 [nTPM]":"24.8","Cell RNA - BEWO [nTPM]":"19.6","Cell RNA - BJ [nTPM]":"25.4","Cell RNA - BJ hTERT+ [nTPM]":"52.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"32.2","Cell RNA - CACO-2 [nTPM]":"13.5","Cell RNA - CAPAN-2 [nTPM]":"12.4","Cell RNA - Daudi [nTPM]":"38.1","Cell RNA - EFO-21 [nTPM]":"17.9","Cell RNA - fHDF\/TERT166 [nTPM]":"35.1","Cell RNA - GAMG [nTPM]":"20.1","Cell RNA - HaCaT [nTPM]":"23.2","Cell RNA - HAP1 [nTPM]":"29.8","Cell RNA - HBEC3-KT [nTPM]":"32.8","Cell RNA - HBF TERT88 [nTPM]":"38.4","Cell RNA - HDLM-2 [nTPM]":"18.1","Cell RNA - HEK 293 [nTPM]":"15.6","Cell RNA - HEL [nTPM]":"16.3","Cell RNA - HeLa [nTPM]":"15.4","Cell RNA - Hep G2 [nTPM]":"19.3","Cell RNA - HHSteC [nTPM]":"9.7","Cell RNA - HL-60 [nTPM]":"15.0","Cell RNA - HMC-1 [nTPM]":"31.7","Cell RNA - HSkMC [nTPM]":"19.3","Cell RNA - hTCEpi [nTPM]":"17.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"23.5","Cell RNA - hTERT-HME1 [nTPM]":"13.8","Cell RNA - hTERT-RPE1 [nTPM]":"61.4","Cell RNA - HUVEC TERT2 [nTPM]":"44.0","Cell RNA - JURKAT [nTPM]":"30.0","Cell RNA - K-562 [nTPM]":"25.9","Cell RNA - Karpas-707 [nTPM]":"11.0","Cell RNA - LHCN-M2 [nTPM]":"23.4","Cell RNA - MCF7 [nTPM]":"27.8","Cell RNA - MOLT-4 [nTPM]":"45.6","Cell RNA - NB-4 [nTPM]":"21.0","Cell RNA - NTERA-2 [nTPM]":"22.0","Cell RNA - OE19 [nTPM]":"22.6","Cell RNA - PC-3 [nTPM]":"12.5","Cell RNA - REH [nTPM]":"10.6","Cell RNA - RH-30 [nTPM]":"32.6","Cell RNA - RPMI-8226 [nTPM]":"51.2","Cell RNA - RPTEC TERT1 [nTPM]":"39.5","Cell RNA - RT4 [nTPM]":"46.8","Cell RNA - SCLC-21H [nTPM]":"13.6","Cell RNA - SH-SY5Y [nTPM]":"11.2","Cell RNA - SiHa [nTPM]":"42.3","Cell RNA - SK-BR-3 [nTPM]":"29.7","Cell RNA - SK-MEL-30 [nTPM]":"60.7","Cell RNA - SuSa [nTPM]":"23.5","Cell RNA - T-47d [nTPM]":"30.6","Cell RNA - THP-1 [nTPM]":"9.8","Cell RNA - TIME [nTPM]":"43.6","Cell RNA - U-138 MG [nTPM]":"23.1","Cell RNA - U-2 OS [nTPM]":"12.5","Cell RNA - U-2197 [nTPM]":"19.6","Cell RNA - U-251 MG [nTPM]":"14.4","Cell RNA - U-266\/70 [nTPM]":"30.0","Cell RNA - U-266\/84 [nTPM]":"32.9","Cell RNA - U-698 [nTPM]":"21.5","Cell RNA - U-87 MG [nTPM]":"26.4","Cell RNA - U-937 [nTPM]":"21.8","Cell RNA - WM-115 [nTPM]":"14.6","Blood RNA - basophil [nTPM]":"8.6","Blood RNA - classical monocyte [nTPM]":"3.8","Blood RNA - eosinophil [nTPM]":"4.4","Blood RNA - gdT-cell [nTPM]":"18.8","Blood RNA - intermediate monocyte [nTPM]":"3.6","Blood RNA - MAIT T-cell [nTPM]":"6.2","Blood RNA - memory B-cell [nTPM]":"3.0","Blood RNA - memory CD4 T-cell [nTPM]":"4.0","Blood RNA - memory CD8 T-cell [nTPM]":"10.3","Blood RNA - myeloid DC [nTPM]":"7.1","Blood RNA - naive B-cell [nTPM]":"4.9","Blood RNA - naive CD4 T-cell [nTPM]":"5.1","Blood RNA - naive CD8 T-cell [nTPM]":"7.9","Blood RNA - neutrophil [nTPM]":"1.4","Blood RNA - NK-cell [nTPM]":"17.0","Blood RNA - non-classical monocyte [nTPM]":"4.6","Blood RNA - plasmacytoid DC [nTPM]":"6.9","Blood RNA - T-reg [nTPM]":"3.3","Blood RNA - total PBMC [nTPM]":"3.7","Brain RNA - amygdala [nTPM]":"18.8","Brain RNA - basal ganglia [nTPM]":"22.2","Brain RNA - cerebellum [nTPM]":"14.4","Brain RNA - cerebral cortex [nTPM]":"20.0","Brain RNA - hippocampal formation [nTPM]":"22.7","Brain RNA - hypothalamus [nTPM]":"10.8","Brain RNA - medulla oblongata [nTPM]":"8.5","Brain RNA - midbrain [nTPM]":"11.1","Brain RNA - pons [nTPM]":"9.7","Brain RNA - spinal cord [nTPM]":"8.9","Brain RNA - thalamus [nTPM]":"12.4","Brain RNA - white matter [nTPM]":"13.3","Single Cell Type RNA - Adipocytes [nTPM]":"25.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"65.0","Single Cell Type RNA - Astrocytes [nTPM]":"35.9","Single Cell Type RNA - B-cells [nTPM]":"42.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Bipolar cells [nTPM]":"23.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"43.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"27.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.7","Single Cell Type RNA - dendritic cells [nTPM]":"107.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"68.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"10.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.7","Single Cell Type RNA - Endothelial cells [nTPM]":"21.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.0","Single Cell Type RNA - Erythroid cells [nTPM]":"19.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"84.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.0","Single Cell Type RNA - Fibroblasts [nTPM]":"18.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"33.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"61.6","Single Cell Type RNA - granulocytes [nTPM]":"122.8","Single Cell Type RNA - Granulosa cells [nTPM]":"24.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.4","Single Cell Type RNA - Hepatocytes [nTPM]":"9.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"46.7","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"83.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"29.6","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"46.7","Single Cell Type RNA - Langerhans cells [nTPM]":"17.6","Single Cell Type RNA - Late spermatids [nTPM]":"3.8","Single Cell Type RNA - Leydig cells [nTPM]":"17.1","Single Cell Type RNA - Macrophages [nTPM]":"41.2","Single Cell Type RNA - Melanocytes [nTPM]":"42.7","Single Cell Type RNA - Microglial cells [nTPM]":"30.0","Single Cell Type RNA - monocytes [nTPM]":"43.5","Single Cell Type RNA - Muller glia cells [nTPM]":"26.9","Single Cell Type RNA - NK-cells [nTPM]":"192.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"135.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.7","Single Cell Type RNA - Paneth cells [nTPM]":"129.3","Single Cell Type RNA - Peritubular cells [nTPM]":"12.8","Single Cell Type RNA - Plasma cells [nTPM]":"63.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"28.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"37.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.9","Single Cell Type RNA - Spermatocytes [nTPM]":"12.4","Single Cell Type RNA - Spermatogonia [nTPM]":"33.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.8","Single Cell Type RNA - T-cells [nTPM]":"63.4","Single Cell Type RNA - Theca cells [nTPM]":"30.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"49.7","Single Cell Type RNA - Urothelial cells [nTPM]":"46.5"},{"Gene":"GNS","Gene synonym":[],"Ensembl":"ENSG00000135677","Gene description":"Glucosamine (N-acetyl)-6-sulfatase","Uniprot":["P15586"],"Chromosome":"12","Position":"64713445-64759431","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Mucopolysaccharidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Kupffer cells":"198.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"228.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013695","CAB026011","HPA048508"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"510000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB026011":null,"HPA013695":"AB_1849741","HPA048508":"AB_2680423"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.76e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.94e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Tissue RNA - adipose tissue [nTPM]":"106.1","Tissue RNA - adrenal gland [nTPM]":"174.7","Tissue RNA - amygdala [nTPM]":"18.0","Tissue RNA - appendix [nTPM]":"56.4","Tissue RNA - basal ganglia [nTPM]":"19.9","Tissue RNA - bone marrow [nTPM]":"25.4","Tissue RNA - breast [nTPM]":"51.9","Tissue RNA - cerebellum [nTPM]":"20.4","Tissue RNA - cerebral cortex [nTPM]":"21.3","Tissue RNA - cervix [nTPM]":"58.9","Tissue RNA - choroid plexus [nTPM]":"80.7","Tissue RNA - colon [nTPM]":"35.3","Tissue RNA - duodenum [nTPM]":"34.6","Tissue RNA - endometrium 1 [nTPM]":"49.5","Tissue RNA - epididymis [nTPM]":"38.5","Tissue RNA - esophagus [nTPM]":"26.2","Tissue RNA - fallopian tube [nTPM]":"43.8","Tissue RNA - gallbladder [nTPM]":"63.7","Tissue RNA - heart muscle [nTPM]":"52.9","Tissue RNA - hippocampal formation [nTPM]":"17.2","Tissue RNA - hypothalamus [nTPM]":"26.4","Tissue RNA - kidney [nTPM]":"132.0","Tissue RNA - liver [nTPM]":"56.2","Tissue RNA - lung [nTPM]":"71.5","Tissue RNA - lymph node [nTPM]":"41.0","Tissue RNA - medulla oblongata [nTPM]":"30.0","Tissue RNA - midbrain [nTPM]":"23.3","Tissue RNA - ovary [nTPM]":"64.3","Tissue RNA - pancreas [nTPM]":"24.1","Tissue RNA - parathyroid gland [nTPM]":"76.8","Tissue RNA - pituitary gland [nTPM]":"23.0","Tissue RNA - placenta [nTPM]":"80.2","Tissue RNA - pons [nTPM]":"25.5","Tissue RNA - prostate [nTPM]":"38.5","Tissue RNA - rectum [nTPM]":"36.9","Tissue RNA - retina [nTPM]":"25.1","Tissue RNA - salivary gland [nTPM]":"32.9","Tissue RNA - seminal vesicle [nTPM]":"47.7","Tissue RNA - skeletal muscle [nTPM]":"30.1","Tissue RNA - skin 1 [nTPM]":"26.3","Tissue RNA - small intestine [nTPM]":"41.4","Tissue RNA - smooth muscle [nTPM]":"69.2","Tissue RNA - spinal cord [nTPM]":"22.5","Tissue RNA - spleen [nTPM]":"51.2","Tissue RNA - stomach 1 [nTPM]":"34.6","Tissue RNA - testis [nTPM]":"31.8","Tissue RNA - thalamus [nTPM]":"27.3","Tissue RNA - thymus [nTPM]":"20.5","Tissue RNA - thyroid gland [nTPM]":"72.8","Tissue RNA - tongue [nTPM]":"29.0","Tissue RNA - tonsil [nTPM]":"26.9","Tissue RNA - urinary bladder [nTPM]":"63.7","Tissue RNA - vagina [nTPM]":"27.6","Tissue RNA - white matter [nTPM]":"31.2","Cell RNA - A-431 [nTPM]":"41.0","Cell RNA - A549 [nTPM]":"61.3","Cell RNA - AF22 [nTPM]":"50.7","Cell RNA - AN3-CA [nTPM]":"81.4","Cell RNA - ASC diff [nTPM]":"240.0","Cell RNA - ASC TERT1 [nTPM]":"145.2","Cell RNA - BEWO [nTPM]":"108.8","Cell RNA - BJ [nTPM]":"92.0","Cell RNA - BJ hTERT+ [nTPM]":"213.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"108.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"117.1","Cell RNA - CACO-2 [nTPM]":"55.9","Cell RNA - CAPAN-2 [nTPM]":"53.3","Cell RNA - Daudi [nTPM]":"17.4","Cell RNA - EFO-21 [nTPM]":"117.0","Cell RNA - fHDF\/TERT166 [nTPM]":"117.8","Cell RNA - GAMG [nTPM]":"133.3","Cell RNA - HaCaT [nTPM]":"33.1","Cell RNA - HAP1 [nTPM]":"49.1","Cell RNA - HBEC3-KT [nTPM]":"52.6","Cell RNA - HBF TERT88 [nTPM]":"119.5","Cell RNA - HDLM-2 [nTPM]":"51.4","Cell RNA - HEK 293 [nTPM]":"36.6","Cell RNA - HEL [nTPM]":"41.4","Cell RNA - HeLa [nTPM]":"45.4","Cell RNA - Hep G2 [nTPM]":"36.4","Cell RNA - HHSteC [nTPM]":"109.3","Cell RNA - HL-60 [nTPM]":"30.6","Cell RNA - HMC-1 [nTPM]":"346.2","Cell RNA - HSkMC [nTPM]":"139.6","Cell RNA - hTCEpi [nTPM]":"62.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"111.5","Cell RNA - hTERT-HME1 [nTPM]":"49.3","Cell RNA - hTERT-RPE1 [nTPM]":"342.0","Cell RNA - HUVEC TERT2 [nTPM]":"200.1","Cell RNA - JURKAT [nTPM]":"24.7","Cell RNA - K-562 [nTPM]":"28.8","Cell RNA - Karpas-707 [nTPM]":"117.2","Cell RNA - LHCN-M2 [nTPM]":"156.8","Cell RNA - MCF7 [nTPM]":"32.6","Cell RNA - MOLT-4 [nTPM]":"8.1","Cell RNA - NB-4 [nTPM]":"17.9","Cell RNA - NTERA-2 [nTPM]":"19.4","Cell RNA - OE19 [nTPM]":"102.8","Cell RNA - PC-3 [nTPM]":"53.2","Cell RNA - REH [nTPM]":"23.8","Cell RNA - RH-30 [nTPM]":"77.3","Cell RNA - RPMI-8226 [nTPM]":"53.7","Cell RNA - RPTEC TERT1 [nTPM]":"91.5","Cell RNA - RT4 [nTPM]":"116.2","Cell RNA - SCLC-21H [nTPM]":"33.7","Cell RNA - SH-SY5Y [nTPM]":"37.3","Cell RNA - SiHa [nTPM]":"119.6","Cell RNA - SK-BR-3 [nTPM]":"56.6","Cell RNA - SK-MEL-30 [nTPM]":"82.4","Cell RNA - SuSa [nTPM]":"65.8","Cell RNA - T-47d [nTPM]":"102.2","Cell RNA - THP-1 [nTPM]":"40.4","Cell RNA - TIME [nTPM]":"185.1","Cell RNA - U-138 MG [nTPM]":"104.5","Cell RNA - U-2 OS [nTPM]":"54.8","Cell RNA - U-2197 [nTPM]":"101.8","Cell RNA - U-251 MG [nTPM]":"54.4","Cell RNA - U-266\/70 [nTPM]":"112.1","Cell RNA - U-266\/84 [nTPM]":"143.4","Cell RNA - U-698 [nTPM]":"14.9","Cell RNA - U-87 MG [nTPM]":"151.1","Cell RNA - U-937 [nTPM]":"58.4","Cell RNA - WM-115 [nTPM]":"72.1","Blood RNA - basophil [nTPM]":"51.7","Blood RNA - classical monocyte [nTPM]":"136.9","Blood RNA - eosinophil [nTPM]":"27.5","Blood RNA - gdT-cell [nTPM]":"29.3","Blood RNA - intermediate monocyte [nTPM]":"158.4","Blood RNA - MAIT T-cell [nTPM]":"21.9","Blood RNA - memory B-cell [nTPM]":"13.0","Blood RNA - memory CD4 T-cell [nTPM]":"15.9","Blood RNA - memory CD8 T-cell [nTPM]":"22.6","Blood RNA - myeloid DC [nTPM]":"78.2","Blood RNA - naive B-cell [nTPM]":"10.0","Blood RNA - naive CD4 T-cell [nTPM]":"16.4","Blood RNA - naive CD8 T-cell [nTPM]":"16.4","Blood RNA - neutrophil [nTPM]":"56.6","Blood RNA - NK-cell [nTPM]":"18.4","Blood RNA - non-classical monocyte [nTPM]":"228.5","Blood RNA - plasmacytoid DC [nTPM]":"19.3","Blood RNA - T-reg [nTPM]":"13.0","Blood RNA - total PBMC [nTPM]":"101.9","Brain RNA - amygdala [nTPM]":"18.0","Brain RNA - basal ganglia [nTPM]":"19.9","Brain RNA - cerebellum [nTPM]":"20.4","Brain RNA - cerebral cortex [nTPM]":"21.3","Brain RNA - hippocampal formation [nTPM]":"17.2","Brain RNA - hypothalamus [nTPM]":"26.4","Brain RNA - medulla oblongata [nTPM]":"30.0","Brain RNA - midbrain [nTPM]":"23.3","Brain RNA - pons [nTPM]":"25.5","Brain RNA - spinal cord [nTPM]":"22.5","Brain RNA - thalamus [nTPM]":"27.3","Brain RNA - white matter [nTPM]":"31.2","Single Cell Type RNA - Adipocytes [nTPM]":"52.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.7","Single Cell Type RNA - Astrocytes [nTPM]":"19.2","Single Cell Type RNA - B-cells [nTPM]":"11.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"10.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"28.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"59.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"24.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"103.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"24.3","Single Cell Type RNA - dendritic cells [nTPM]":"18.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"36.2","Single Cell Type RNA - Early spermatids [nTPM]":"24.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"26.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"25.5","Single Cell Type RNA - Endothelial cells [nTPM]":"50.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"41.9","Single Cell Type RNA - Erythroid cells [nTPM]":"15.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.7","Single Cell Type RNA - Fibroblasts [nTPM]":"40.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"32.9","Single Cell Type RNA - granulocytes [nTPM]":"48.1","Single Cell Type RNA - Granulosa cells [nTPM]":"36.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"58.5","Single Cell Type RNA - Hepatocytes [nTPM]":"57.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"81.0","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"31.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.6","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"198.8","Single Cell Type RNA - Langerhans cells [nTPM]":"46.5","Single Cell Type RNA - Late spermatids [nTPM]":"24.5","Single Cell Type RNA - Leydig cells [nTPM]":"34.8","Single Cell Type RNA - Macrophages [nTPM]":"107.8","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"27.2","Single Cell Type RNA - monocytes [nTPM]":"79.0","Single Cell Type RNA - Muller glia cells [nTPM]":"20.1","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.0","Single Cell Type RNA - Paneth cells [nTPM]":"15.7","Single Cell Type RNA - Peritubular cells [nTPM]":"37.2","Single Cell Type RNA - Plasma cells [nTPM]":"16.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"60.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"64.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"42.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"24.9","Single Cell Type RNA - Spermatocytes [nTPM]":"11.3","Single Cell Type RNA - Spermatogonia [nTPM]":"7.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"29.1","Single Cell Type RNA - T-cells [nTPM]":"13.2","Single Cell Type RNA - Theca cells [nTPM]":"30.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.2","Single Cell Type RNA - Urothelial cells [nTPM]":"19.2"},{"Gene":"GOLGA5","Gene synonym":["golgin-84","GOLIM5","ret-II","rfg5"],"Ensembl":"ENSG00000066455","Gene description":"Golgin A5","Uniprot":["Q8TBA6"],"Chromosome":"14","Position":"92794305-92839947","Protein class":["Cancer-related genes","Disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000992","HPA063876"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA000992":"AB_1079009","HPA063876":"AB_2685140"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Tissue RNA - adipose tissue [nTPM]":"26.0","Tissue RNA - adrenal gland [nTPM]":"23.3","Tissue RNA - amygdala [nTPM]":"21.4","Tissue RNA - appendix [nTPM]":"18.2","Tissue RNA - basal ganglia [nTPM]":"23.7","Tissue RNA - bone marrow [nTPM]":"10.4","Tissue RNA - breast [nTPM]":"33.1","Tissue RNA - cerebellum [nTPM]":"22.4","Tissue RNA - cerebral cortex [nTPM]":"26.4","Tissue RNA - cervix [nTPM]":"32.2","Tissue RNA - choroid plexus [nTPM]":"23.9","Tissue RNA - colon [nTPM]":"26.4","Tissue RNA - duodenum [nTPM]":"23.3","Tissue RNA - endometrium 1 [nTPM]":"21.9","Tissue RNA - epididymis [nTPM]":"54.2","Tissue RNA - esophagus [nTPM]":"25.0","Tissue RNA - fallopian tube [nTPM]":"19.2","Tissue RNA - gallbladder [nTPM]":"24.0","Tissue RNA - heart muscle [nTPM]":"21.5","Tissue RNA - hippocampal formation [nTPM]":"20.8","Tissue RNA - hypothalamus [nTPM]":"22.3","Tissue RNA - kidney [nTPM]":"25.5","Tissue RNA - liver [nTPM]":"54.3","Tissue RNA - lung [nTPM]":"22.4","Tissue RNA - lymph node [nTPM]":"18.8","Tissue RNA - medulla oblongata [nTPM]":"22.6","Tissue RNA - midbrain [nTPM]":"22.4","Tissue RNA - ovary [nTPM]":"20.6","Tissue RNA - pancreas [nTPM]":"32.2","Tissue RNA - parathyroid gland [nTPM]":"33.6","Tissue RNA - pituitary gland [nTPM]":"23.5","Tissue RNA - placenta [nTPM]":"28.2","Tissue RNA - pons [nTPM]":"23.1","Tissue RNA - prostate [nTPM]":"31.2","Tissue RNA - rectum [nTPM]":"32.5","Tissue RNA - retina [nTPM]":"15.8","Tissue RNA - salivary gland [nTPM]":"32.4","Tissue RNA - seminal vesicle [nTPM]":"25.8","Tissue RNA - skeletal muscle [nTPM]":"26.9","Tissue RNA - skin 1 [nTPM]":"23.3","Tissue RNA - small intestine [nTPM]":"22.9","Tissue RNA - smooth muscle [nTPM]":"26.0","Tissue RNA - spinal cord [nTPM]":"22.6","Tissue RNA - spleen [nTPM]":"19.1","Tissue RNA - stomach 1 [nTPM]":"32.9","Tissue RNA - testis [nTPM]":"34.3","Tissue RNA - thalamus [nTPM]":"22.1","Tissue RNA - thymus [nTPM]":"16.9","Tissue RNA - thyroid gland [nTPM]":"33.2","Tissue RNA - tongue [nTPM]":"20.0","Tissue RNA - tonsil [nTPM]":"23.3","Tissue RNA - urinary bladder [nTPM]":"24.1","Tissue RNA - vagina [nTPM]":"19.6","Tissue RNA - white matter [nTPM]":"25.9","Cell RNA - A-431 [nTPM]":"32.4","Cell RNA - A549 [nTPM]":"29.4","Cell RNA - AF22 [nTPM]":"25.9","Cell RNA - AN3-CA [nTPM]":"23.7","Cell RNA - ASC diff [nTPM]":"53.1","Cell RNA - ASC TERT1 [nTPM]":"71.4","Cell RNA - BEWO [nTPM]":"44.3","Cell RNA - BJ [nTPM]":"43.9","Cell RNA - BJ hTERT+ [nTPM]":"80.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"41.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"49.2","Cell RNA - CACO-2 [nTPM]":"21.8","Cell RNA - CAPAN-2 [nTPM]":"43.4","Cell RNA - Daudi [nTPM]":"21.0","Cell RNA - EFO-21 [nTPM]":"35.1","Cell RNA - fHDF\/TERT166 [nTPM]":"70.2","Cell RNA - GAMG [nTPM]":"29.2","Cell RNA - HaCaT [nTPM]":"33.4","Cell RNA - HAP1 [nTPM]":"23.1","Cell RNA - HBEC3-KT [nTPM]":"35.9","Cell RNA - HBF TERT88 [nTPM]":"56.6","Cell RNA - HDLM-2 [nTPM]":"25.8","Cell RNA - HEK 293 [nTPM]":"11.2","Cell RNA - HEL [nTPM]":"19.9","Cell RNA - HeLa [nTPM]":"14.0","Cell RNA - Hep G2 [nTPM]":"29.3","Cell RNA - HHSteC [nTPM]":"61.5","Cell RNA - HL-60 [nTPM]":"23.3","Cell RNA - HMC-1 [nTPM]":"31.8","Cell RNA - HSkMC [nTPM]":"55.1","Cell RNA - hTCEpi [nTPM]":"63.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"29.5","Cell RNA - hTERT-HME1 [nTPM]":"60.6","Cell RNA - hTERT-RPE1 [nTPM]":"46.2","Cell RNA - HUVEC TERT2 [nTPM]":"42.0","Cell RNA - JURKAT [nTPM]":"21.8","Cell RNA - K-562 [nTPM]":"17.7","Cell RNA - Karpas-707 [nTPM]":"27.3","Cell RNA - LHCN-M2 [nTPM]":"46.5","Cell RNA - MCF7 [nTPM]":"60.1","Cell RNA - MOLT-4 [nTPM]":"18.1","Cell RNA - NB-4 [nTPM]":"19.6","Cell RNA - NTERA-2 [nTPM]":"16.1","Cell RNA - OE19 [nTPM]":"70.2","Cell RNA - PC-3 [nTPM]":"31.0","Cell RNA - REH [nTPM]":"13.9","Cell RNA - RH-30 [nTPM]":"37.9","Cell RNA - RPMI-8226 [nTPM]":"21.1","Cell RNA - RPTEC TERT1 [nTPM]":"42.8","Cell RNA - RT4 [nTPM]":"38.9","Cell RNA - SCLC-21H [nTPM]":"18.4","Cell RNA - SH-SY5Y [nTPM]":"26.0","Cell RNA - SiHa [nTPM]":"40.0","Cell RNA - SK-BR-3 [nTPM]":"29.6","Cell RNA - SK-MEL-30 [nTPM]":"45.7","Cell RNA - SuSa [nTPM]":"35.7","Cell RNA - T-47d [nTPM]":"51.0","Cell RNA - THP-1 [nTPM]":"25.6","Cell RNA - TIME [nTPM]":"35.0","Cell RNA - U-138 MG [nTPM]":"23.9","Cell RNA - U-2 OS [nTPM]":"15.6","Cell RNA - U-2197 [nTPM]":"31.3","Cell RNA - U-251 MG [nTPM]":"22.2","Cell RNA - U-266\/70 [nTPM]":"33.3","Cell RNA - U-266\/84 [nTPM]":"27.6","Cell RNA - U-698 [nTPM]":"18.2","Cell RNA - U-87 MG [nTPM]":"54.9","Cell RNA - U-937 [nTPM]":"18.2","Cell RNA - WM-115 [nTPM]":"40.8","Blood RNA - basophil [nTPM]":"10.4","Blood RNA - classical monocyte [nTPM]":"10.0","Blood RNA - eosinophil [nTPM]":"23.6","Blood RNA - gdT-cell [nTPM]":"10.3","Blood RNA - intermediate monocyte [nTPM]":"13.0","Blood RNA - MAIT T-cell [nTPM]":"11.8","Blood RNA - memory B-cell [nTPM]":"9.5","Blood RNA - memory CD4 T-cell [nTPM]":"10.4","Blood RNA - memory CD8 T-cell [nTPM]":"10.6","Blood RNA - myeloid DC [nTPM]":"9.9","Blood RNA - naive B-cell [nTPM]":"9.5","Blood RNA - naive CD4 T-cell [nTPM]":"9.2","Blood RNA - naive CD8 T-cell [nTPM]":"8.1","Blood RNA - neutrophil [nTPM]":"8.8","Blood RNA - NK-cell [nTPM]":"8.7","Blood RNA - non-classical monocyte [nTPM]":"11.9","Blood RNA - plasmacytoid DC [nTPM]":"9.1","Blood RNA - T-reg [nTPM]":"12.9","Blood RNA - total PBMC [nTPM]":"6.7","Brain RNA - amygdala [nTPM]":"21.4","Brain RNA - basal ganglia [nTPM]":"23.7","Brain RNA - cerebellum [nTPM]":"22.4","Brain RNA - cerebral cortex [nTPM]":"26.4","Brain RNA - hippocampal formation [nTPM]":"20.8","Brain RNA - hypothalamus [nTPM]":"22.3","Brain RNA - medulla oblongata [nTPM]":"22.6","Brain RNA - midbrain [nTPM]":"22.4","Brain RNA - pons [nTPM]":"23.1","Brain RNA - spinal cord [nTPM]":"22.6","Brain RNA - thalamus [nTPM]":"22.1","Brain RNA - white matter [nTPM]":"25.9","Single Cell Type RNA - Adipocytes [nTPM]":"18.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.3","Single Cell Type RNA - Astrocytes [nTPM]":"8.8","Single Cell Type RNA - B-cells [nTPM]":"15.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"16.5","Single Cell Type RNA - Bipolar cells [nTPM]":"7.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"26.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"19.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.7","Single Cell Type RNA - dendritic cells [nTPM]":"17.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"29.4","Single Cell Type RNA - Ductal cells [nTPM]":"25.3","Single Cell Type RNA - Early spermatids [nTPM]":"31.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"24.6","Single Cell Type RNA - Endothelial cells [nTPM]":"16.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.3","Single Cell Type RNA - Erythroid cells [nTPM]":"15.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"32.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"32.0","Single Cell Type RNA - Fibroblasts [nTPM]":"21.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"33.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.7","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"29.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.9","Single Cell Type RNA - Hepatocytes [nTPM]":"33.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.4","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.6","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"14.7","Single Cell Type RNA - Langerhans cells [nTPM]":"10.3","Single Cell Type RNA - Late spermatids [nTPM]":"18.5","Single Cell Type RNA - Leydig cells [nTPM]":"23.0","Single Cell Type RNA - Macrophages [nTPM]":"14.6","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"18.2","Single Cell Type RNA - Muller glia cells [nTPM]":"15.6","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"28.9","Single Cell Type RNA - Paneth cells [nTPM]":"12.0","Single Cell Type RNA - Peritubular cells [nTPM]":"25.2","Single Cell Type RNA - Plasma cells [nTPM]":"29.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"19.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"24.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.7","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.3","Single Cell Type RNA - Spermatocytes [nTPM]":"34.1","Single Cell Type RNA - Spermatogonia [nTPM]":"37.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"50.3","Single Cell Type RNA - T-cells [nTPM]":"15.9","Single Cell Type RNA - Theca cells [nTPM]":"15.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.5","Single Cell Type RNA - Urothelial cells [nTPM]":"16.5"},{"Gene":"GOPC","Gene synonym":["CAL","dJ94G16.2","FIG","GOPC1","PIST"],"Ensembl":"ENSG00000047932","Gene description":"Golgi associated PDZ and coiled-coil motif containing","Uniprot":["Q9HD26"],"Chromosome":"6","Position":"117560269-117602542","Protein class":["Cancer-related genes","Disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019477","HPA024018"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA019477":"AB_1849890","HPA024018":"AB_1849891"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.5","Tissue RNA - adrenal gland [nTPM]":"14.2","Tissue RNA - amygdala [nTPM]":"14.6","Tissue RNA - appendix [nTPM]":"15.8","Tissue RNA - basal ganglia [nTPM]":"14.9","Tissue RNA - bone marrow [nTPM]":"7.1","Tissue RNA - breast [nTPM]":"20.2","Tissue RNA - cerebellum [nTPM]":"15.6","Tissue RNA - cerebral cortex [nTPM]":"18.0","Tissue RNA - cervix [nTPM]":"23.4","Tissue RNA - choroid plexus [nTPM]":"11.0","Tissue RNA - colon [nTPM]":"18.7","Tissue RNA - duodenum [nTPM]":"12.2","Tissue RNA - endometrium 1 [nTPM]":"23.5","Tissue RNA - epididymis [nTPM]":"18.0","Tissue RNA - esophagus [nTPM]":"12.1","Tissue RNA - fallopian tube [nTPM]":"17.4","Tissue RNA - gallbladder [nTPM]":"16.3","Tissue RNA - heart muscle [nTPM]":"22.1","Tissue RNA - hippocampal formation [nTPM]":"15.9","Tissue RNA - hypothalamus [nTPM]":"13.3","Tissue RNA - kidney [nTPM]":"14.5","Tissue RNA - liver [nTPM]":"16.4","Tissue RNA - lung [nTPM]":"13.6","Tissue RNA - lymph node [nTPM]":"19.9","Tissue RNA - medulla oblongata [nTPM]":"12.5","Tissue RNA - midbrain [nTPM]":"12.5","Tissue RNA - ovary [nTPM]":"25.6","Tissue RNA - pancreas [nTPM]":"12.7","Tissue RNA - parathyroid gland [nTPM]":"22.1","Tissue RNA - pituitary gland [nTPM]":"16.1","Tissue RNA - placenta [nTPM]":"19.9","Tissue RNA - pons [nTPM]":"13.1","Tissue RNA - prostate [nTPM]":"16.2","Tissue RNA - rectum [nTPM]":"20.3","Tissue RNA - retina [nTPM]":"13.5","Tissue RNA - salivary gland [nTPM]":"14.3","Tissue RNA - seminal vesicle [nTPM]":"17.3","Tissue RNA - skeletal muscle [nTPM]":"15.8","Tissue RNA - skin 1 [nTPM]":"18.7","Tissue RNA - small intestine [nTPM]":"15.0","Tissue RNA - smooth muscle [nTPM]":"18.4","Tissue RNA - spinal cord [nTPM]":"13.6","Tissue RNA - spleen [nTPM]":"16.9","Tissue RNA - stomach 1 [nTPM]":"14.9","Tissue RNA - testis [nTPM]":"17.7","Tissue RNA - thalamus [nTPM]":"12.6","Tissue RNA - thymus [nTPM]":"21.0","Tissue RNA - thyroid gland [nTPM]":"23.9","Tissue RNA - tongue [nTPM]":"17.4","Tissue RNA - tonsil [nTPM]":"17.2","Tissue RNA - urinary bladder [nTPM]":"15.1","Tissue RNA - vagina [nTPM]":"14.7","Tissue RNA - white matter [nTPM]":"16.8","Cell RNA - A-431 [nTPM]":"14.1","Cell RNA - A549 [nTPM]":"15.0","Cell RNA - AF22 [nTPM]":"19.1","Cell RNA - AN3-CA [nTPM]":"25.6","Cell RNA - ASC diff [nTPM]":"40.1","Cell RNA - ASC TERT1 [nTPM]":"47.9","Cell RNA - BEWO [nTPM]":"30.3","Cell RNA - BJ [nTPM]":"57.1","Cell RNA - BJ hTERT+ [nTPM]":"41.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"30.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"31.5","Cell RNA - CACO-2 [nTPM]":"23.1","Cell RNA - CAPAN-2 [nTPM]":"15.5","Cell RNA - Daudi [nTPM]":"42.2","Cell RNA - EFO-21 [nTPM]":"24.3","Cell RNA - fHDF\/TERT166 [nTPM]":"32.4","Cell RNA - GAMG [nTPM]":"60.4","Cell RNA - HaCaT [nTPM]":"31.2","Cell RNA - HAP1 [nTPM]":"37.2","Cell RNA - HBEC3-KT [nTPM]":"27.6","Cell RNA - HBF TERT88 [nTPM]":"42.8","Cell RNA - HDLM-2 [nTPM]":"21.2","Cell RNA - HEK 293 [nTPM]":"20.8","Cell RNA - HEL [nTPM]":"38.7","Cell RNA - HeLa [nTPM]":"39.9","Cell RNA - Hep G2 [nTPM]":"37.5","Cell RNA - HHSteC [nTPM]":"42.4","Cell RNA - HL-60 [nTPM]":"52.2","Cell RNA - HMC-1 [nTPM]":"24.8","Cell RNA - HSkMC [nTPM]":"57.4","Cell RNA - hTCEpi [nTPM]":"74.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.8","Cell RNA - hTERT-HME1 [nTPM]":"65.7","Cell RNA - hTERT-RPE1 [nTPM]":"60.6","Cell RNA - HUVEC TERT2 [nTPM]":"26.5","Cell RNA - JURKAT [nTPM]":"29.0","Cell RNA - K-562 [nTPM]":"36.7","Cell RNA - Karpas-707 [nTPM]":"16.8","Cell RNA - LHCN-M2 [nTPM]":"62.2","Cell RNA - MCF7 [nTPM]":"12.9","Cell RNA - MOLT-4 [nTPM]":"21.8","Cell RNA - NB-4 [nTPM]":"40.3","Cell RNA - NTERA-2 [nTPM]":"16.5","Cell RNA - OE19 [nTPM]":"24.0","Cell RNA - PC-3 [nTPM]":"16.0","Cell RNA - REH [nTPM]":"33.0","Cell RNA - RH-30 [nTPM]":"37.0","Cell RNA - RPMI-8226 [nTPM]":"30.8","Cell RNA - RPTEC TERT1 [nTPM]":"23.3","Cell RNA - RT4 [nTPM]":"12.9","Cell RNA - SCLC-21H [nTPM]":"26.7","Cell RNA - SH-SY5Y [nTPM]":"21.0","Cell RNA - SiHa [nTPM]":"57.6","Cell RNA - SK-BR-3 [nTPM]":"19.7","Cell RNA - SK-MEL-30 [nTPM]":"15.8","Cell RNA - SuSa [nTPM]":"36.3","Cell RNA - T-47d [nTPM]":"14.3","Cell RNA - THP-1 [nTPM]":"49.7","Cell RNA - TIME [nTPM]":"31.8","Cell RNA - U-138 MG [nTPM]":"2.2","Cell RNA - U-2 OS [nTPM]":"27.9","Cell RNA - U-2197 [nTPM]":"28.5","Cell RNA - U-251 MG [nTPM]":"62.6","Cell RNA - U-266\/70 [nTPM]":"29.9","Cell RNA - U-266\/84 [nTPM]":"28.8","Cell RNA - U-698 [nTPM]":"35.4","Cell RNA - U-87 MG [nTPM]":"37.9","Cell RNA - U-937 [nTPM]":"43.4","Cell RNA - WM-115 [nTPM]":"23.9","Blood RNA - basophil [nTPM]":"10.5","Blood RNA - classical monocyte [nTPM]":"4.2","Blood RNA - eosinophil [nTPM]":"3.2","Blood RNA - gdT-cell [nTPM]":"6.7","Blood RNA - intermediate monocyte [nTPM]":"3.9","Blood RNA - MAIT T-cell [nTPM]":"9.3","Blood RNA - memory B-cell [nTPM]":"7.9","Blood RNA - memory CD4 T-cell [nTPM]":"7.1","Blood RNA - memory CD8 T-cell [nTPM]":"7.1","Blood RNA - myeloid DC [nTPM]":"5.5","Blood RNA - naive B-cell [nTPM]":"7.7","Blood RNA - naive CD4 T-cell [nTPM]":"8.2","Blood RNA - naive CD8 T-cell [nTPM]":"8.5","Blood RNA - neutrophil [nTPM]":"2.9","Blood RNA - NK-cell [nTPM]":"9.2","Blood RNA - non-classical monocyte [nTPM]":"4.7","Blood RNA - plasmacytoid DC [nTPM]":"9.2","Blood RNA - T-reg [nTPM]":"7.7","Blood RNA - total PBMC [nTPM]":"4.1","Brain RNA - amygdala [nTPM]":"14.6","Brain RNA - basal ganglia [nTPM]":"14.9","Brain RNA - cerebellum [nTPM]":"15.6","Brain RNA - cerebral cortex [nTPM]":"18.0","Brain RNA - hippocampal formation [nTPM]":"15.9","Brain RNA - hypothalamus [nTPM]":"13.3","Brain RNA - medulla oblongata [nTPM]":"12.5","Brain RNA - midbrain [nTPM]":"12.5","Brain RNA - pons [nTPM]":"13.1","Brain RNA - spinal cord [nTPM]":"13.6","Brain RNA - thalamus [nTPM]":"12.6","Brain RNA - white matter [nTPM]":"16.8","Single Cell Type RNA - Adipocytes [nTPM]":"43.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"22.7","Single Cell Type RNA - Astrocytes [nTPM]":"46.4","Single Cell Type RNA - B-cells [nTPM]":"33.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"46.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"25.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"63.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"46.7","Single Cell Type RNA - Bipolar cells [nTPM]":"59.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"47.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"67.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"46.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"34.3","Single Cell Type RNA - Club cells [nTPM]":"32.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"77.0","Single Cell Type RNA - dendritic cells [nTPM]":"28.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"40.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"27.4","Single Cell Type RNA - Ductal cells [nTPM]":"27.9","Single Cell Type RNA - Early spermatids [nTPM]":"35.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"30.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"77.4","Single Cell Type RNA - Endothelial cells [nTPM]":"38.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"33.6","Single Cell Type RNA - Erythroid cells [nTPM]":"26.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"52.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"62.4","Single Cell Type RNA - Fibroblasts [nTPM]":"48.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"30.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"30.6","Single Cell Type RNA - granulocytes [nTPM]":"31.1","Single Cell Type RNA - Granulosa cells [nTPM]":"50.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"35.0","Single Cell Type RNA - Hepatocytes [nTPM]":"38.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"38.5","Single Cell Type RNA - Horizontal cells [nTPM]":"74.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"46.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"65.2","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"24.2","Single Cell Type RNA - Langerhans cells [nTPM]":"22.9","Single Cell Type RNA - Late spermatids [nTPM]":"13.7","Single Cell Type RNA - Leydig cells [nTPM]":"42.3","Single Cell Type RNA - Macrophages [nTPM]":"27.0","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"32.8","Single Cell Type RNA - monocytes [nTPM]":"24.1","Single Cell Type RNA - Muller glia cells [nTPM]":"39.3","Single Cell Type RNA - NK-cells [nTPM]":"35.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"73.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"64.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.1","Single Cell Type RNA - Paneth cells [nTPM]":"40.9","Single Cell Type RNA - Peritubular cells [nTPM]":"42.2","Single Cell Type RNA - Plasma cells [nTPM]":"38.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"40.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"27.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"35.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"35.9","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"50.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"44.3","Single Cell Type RNA - Spermatocytes [nTPM]":"115.6","Single Cell Type RNA - Spermatogonia [nTPM]":"51.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"36.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"59.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"52.3","Single Cell Type RNA - T-cells [nTPM]":"38.7","Single Cell Type RNA - Theca cells [nTPM]":"43.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"37.7","Single Cell Type RNA - Urothelial cells [nTPM]":"27.3"},{"Gene":"GOT2","Gene synonym":["KAT4","KATIV","KYAT4","mitAAT"],"Ensembl":"ENSG00000125166","Gene description":"Glutamic-oxaloacetic transaminase 2","Uniprot":["P00505"],"Chromosome":"16","Position":"58707131-58734342","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Aminotransferase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"698.4","tongue":"726.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"341.9","Hepatocytes":"176.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018139","HPA058537"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2800000","Blood expression cluster":"Cluster 13: T-cells - Unknown function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018139":"AB_1849903","HPA058537":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.61e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.75e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.90e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Tissue RNA - adipose tissue [nTPM]":"19.6","Tissue RNA - adrenal gland [nTPM]":"73.9","Tissue RNA - amygdala [nTPM]":"52.4","Tissue RNA - appendix [nTPM]":"27.4","Tissue RNA - basal ganglia [nTPM]":"55.9","Tissue RNA - bone marrow [nTPM]":"21.1","Tissue RNA - breast [nTPM]":"36.3","Tissue RNA - cerebellum [nTPM]":"62.5","Tissue RNA - cerebral cortex [nTPM]":"66.9","Tissue RNA - cervix [nTPM]":"34.1","Tissue RNA - choroid plexus [nTPM]":"129.4","Tissue RNA - colon [nTPM]":"57.6","Tissue RNA - duodenum [nTPM]":"37.4","Tissue RNA - endometrium 1 [nTPM]":"36.5","Tissue RNA - epididymis [nTPM]":"66.3","Tissue RNA - esophagus [nTPM]":"66.9","Tissue RNA - fallopian tube [nTPM]":"46.7","Tissue RNA - gallbladder [nTPM]":"24.1","Tissue RNA - heart muscle [nTPM]":"313.2","Tissue RNA - hippocampal formation [nTPM]":"57.9","Tissue RNA - hypothalamus [nTPM]":"59.3","Tissue RNA - kidney [nTPM]":"88.0","Tissue RNA - liver [nTPM]":"321.4","Tissue RNA - lung [nTPM]":"25.2","Tissue RNA - lymph node [nTPM]":"35.6","Tissue RNA - medulla oblongata [nTPM]":"60.6","Tissue RNA - midbrain [nTPM]":"51.0","Tissue RNA - ovary [nTPM]":"29.4","Tissue RNA - pancreas [nTPM]":"33.2","Tissue RNA - parathyroid gland [nTPM]":"98.6","Tissue RNA - pituitary gland [nTPM]":"46.7","Tissue RNA - placenta [nTPM]":"24.7","Tissue RNA - pons [nTPM]":"62.5","Tissue RNA - prostate [nTPM]":"59.0","Tissue RNA - rectum [nTPM]":"65.0","Tissue RNA - retina [nTPM]":"91.4","Tissue RNA - salivary gland [nTPM]":"47.7","Tissue RNA - seminal vesicle [nTPM]":"65.7","Tissue RNA - skeletal muscle [nTPM]":"698.4","Tissue RNA - skin 1 [nTPM]":"41.1","Tissue RNA - small intestine [nTPM]":"35.7","Tissue RNA - smooth muscle [nTPM]":"46.7","Tissue RNA - spinal cord [nTPM]":"50.1","Tissue RNA - spleen [nTPM]":"28.5","Tissue RNA - stomach 1 [nTPM]":"54.9","Tissue RNA - testis [nTPM]":"28.9","Tissue RNA - thalamus [nTPM]":"58.7","Tissue RNA - thymus [nTPM]":"35.9","Tissue RNA - thyroid gland [nTPM]":"42.6","Tissue RNA - tongue [nTPM]":"726.8","Tissue RNA - tonsil [nTPM]":"57.0","Tissue RNA - urinary bladder [nTPM]":"57.0","Tissue RNA - vagina [nTPM]":"45.1","Tissue RNA - white matter [nTPM]":"61.0","Cell RNA - A-431 [nTPM]":"137.2","Cell RNA - A549 [nTPM]":"182.4","Cell RNA - AF22 [nTPM]":"93.8","Cell RNA - AN3-CA [nTPM]":"114.8","Cell RNA - ASC diff [nTPM]":"66.6","Cell RNA - ASC TERT1 [nTPM]":"59.8","Cell RNA - BEWO [nTPM]":"122.0","Cell RNA - BJ [nTPM]":"101.4","Cell RNA - BJ hTERT+ [nTPM]":"108.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"197.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"107.7","Cell RNA - CACO-2 [nTPM]":"158.9","Cell RNA - CAPAN-2 [nTPM]":"120.1","Cell RNA - Daudi [nTPM]":"302.3","Cell RNA - EFO-21 [nTPM]":"117.3","Cell RNA - fHDF\/TERT166 [nTPM]":"114.6","Cell RNA - GAMG [nTPM]":"86.5","Cell RNA - HaCaT [nTPM]":"195.5","Cell RNA - HAP1 [nTPM]":"203.2","Cell RNA - HBEC3-KT [nTPM]":"199.2","Cell RNA - HBF TERT88 [nTPM]":"250.1","Cell RNA - HDLM-2 [nTPM]":"83.1","Cell RNA - HEK 293 [nTPM]":"182.0","Cell RNA - HEL [nTPM]":"81.4","Cell RNA - HeLa [nTPM]":"92.1","Cell RNA - Hep G2 [nTPM]":"179.3","Cell RNA - HHSteC [nTPM]":"84.2","Cell RNA - HL-60 [nTPM]":"132.3","Cell RNA - HMC-1 [nTPM]":"71.9","Cell RNA - HSkMC [nTPM]":"58.4","Cell RNA - hTCEpi [nTPM]":"110.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"125.2","Cell RNA - hTERT-HME1 [nTPM]":"108.2","Cell RNA - hTERT-RPE1 [nTPM]":"112.4","Cell RNA - HUVEC TERT2 [nTPM]":"201.8","Cell RNA - JURKAT [nTPM]":"141.9","Cell RNA - K-562 [nTPM]":"167.0","Cell RNA - Karpas-707 [nTPM]":"30.6","Cell RNA - LHCN-M2 [nTPM]":"102.2","Cell RNA - MCF7 [nTPM]":"122.5","Cell RNA - MOLT-4 [nTPM]":"164.0","Cell RNA - NB-4 [nTPM]":"128.0","Cell RNA - NTERA-2 [nTPM]":"127.7","Cell RNA - OE19 [nTPM]":"90.8","Cell RNA - PC-3 [nTPM]":"338.0","Cell RNA - REH [nTPM]":"177.8","Cell RNA - RH-30 [nTPM]":"142.7","Cell RNA - RPMI-8226 [nTPM]":"291.1","Cell RNA - RPTEC TERT1 [nTPM]":"187.9","Cell RNA - RT4 [nTPM]":"197.7","Cell RNA - SCLC-21H [nTPM]":"148.2","Cell RNA - SH-SY5Y [nTPM]":"107.6","Cell RNA - SiHa [nTPM]":"195.2","Cell RNA - SK-BR-3 [nTPM]":"208.5","Cell RNA - SK-MEL-30 [nTPM]":"74.8","Cell RNA - SuSa [nTPM]":"84.2","Cell RNA - T-47d [nTPM]":"105.5","Cell RNA - THP-1 [nTPM]":"42.7","Cell RNA - TIME [nTPM]":"82.3","Cell RNA - U-138 MG [nTPM]":"71.4","Cell RNA - U-2 OS [nTPM]":"129.3","Cell RNA - U-2197 [nTPM]":"56.2","Cell RNA - U-251 MG [nTPM]":"132.4","Cell RNA - U-266\/70 [nTPM]":"69.9","Cell RNA - U-266\/84 [nTPM]":"68.6","Cell RNA - U-698 [nTPM]":"247.4","Cell RNA - U-87 MG [nTPM]":"76.7","Cell RNA - U-937 [nTPM]":"130.9","Cell RNA - WM-115 [nTPM]":"73.8","Blood RNA - basophil [nTPM]":"4.6","Blood RNA - classical monocyte [nTPM]":"20.6","Blood RNA - eosinophil [nTPM]":"7.4","Blood RNA - gdT-cell [nTPM]":"28.3","Blood RNA - intermediate monocyte [nTPM]":"16.9","Blood RNA - MAIT T-cell [nTPM]":"43.7","Blood RNA - memory B-cell [nTPM]":"26.5","Blood RNA - memory CD4 T-cell [nTPM]":"33.1","Blood RNA - memory CD8 T-cell [nTPM]":"34.1","Blood RNA - myeloid DC [nTPM]":"34.7","Blood RNA - naive B-cell [nTPM]":"22.3","Blood RNA - naive CD4 T-cell [nTPM]":"30.1","Blood RNA - naive CD8 T-cell [nTPM]":"28.4","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"30.2","Blood RNA - non-classical monocyte [nTPM]":"18.4","Blood RNA - plasmacytoid DC [nTPM]":"30.0","Blood RNA - T-reg [nTPM]":"48.7","Blood RNA - total PBMC [nTPM]":"31.2","Brain RNA - amygdala [nTPM]":"52.4","Brain RNA - basal ganglia [nTPM]":"55.9","Brain RNA - cerebellum [nTPM]":"62.5","Brain RNA - cerebral cortex [nTPM]":"66.9","Brain RNA - hippocampal formation [nTPM]":"57.9","Brain RNA - hypothalamus [nTPM]":"59.3","Brain RNA - medulla oblongata [nTPM]":"60.6","Brain RNA - midbrain [nTPM]":"51.0","Brain RNA - pons [nTPM]":"62.5","Brain RNA - spinal cord [nTPM]":"50.1","Brain RNA - thalamus [nTPM]":"58.7","Brain RNA - white matter [nTPM]":"61.0","Single Cell Type RNA - Adipocytes [nTPM]":"15.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.8","Single Cell Type RNA - Astrocytes [nTPM]":"11.8","Single Cell Type RNA - B-cells [nTPM]":"19.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"32.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"37.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"39.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"34.1","Single Cell Type RNA - Bipolar cells [nTPM]":"34.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"27.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"341.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"22.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"77.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"42.6","Single Cell Type RNA - dendritic cells [nTPM]":"11.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"42.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"56.7","Single Cell Type RNA - Ductal cells [nTPM]":"50.8","Single Cell Type RNA - Early spermatids [nTPM]":"4.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"30.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.0","Single Cell Type RNA - Endothelial cells [nTPM]":"23.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.5","Single Cell Type RNA - Erythroid cells [nTPM]":"39.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"24.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"42.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"38.8","Single Cell Type RNA - Fibroblasts [nTPM]":"21.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"30.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.4","Single Cell Type RNA - granulocytes [nTPM]":"14.5","Single Cell Type RNA - Granulosa cells [nTPM]":"37.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.2","Single Cell Type RNA - Hepatocytes [nTPM]":"176.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"39.1","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"27.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"33.5","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"17.0","Single Cell Type RNA - Langerhans cells [nTPM]":"15.1","Single Cell Type RNA - Late spermatids [nTPM]":"8.1","Single Cell Type RNA - Leydig cells [nTPM]":"18.0","Single Cell Type RNA - Macrophages [nTPM]":"13.5","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"12.7","Single Cell Type RNA - Muller glia cells [nTPM]":"16.1","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"40.3","Single Cell Type RNA - Paneth cells [nTPM]":"13.3","Single Cell Type RNA - Peritubular cells [nTPM]":"22.6","Single Cell Type RNA - Plasma cells [nTPM]":"39.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"38.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"27.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"63.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"48.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"24.0","Single Cell Type RNA - Spermatocytes [nTPM]":"11.9","Single Cell Type RNA - Spermatogonia [nTPM]":"15.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"68.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"30.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.7","Single Cell Type RNA - T-cells [nTPM]":"17.4","Single Cell Type RNA - Theca cells [nTPM]":"36.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"54.4","Single Cell Type RNA - Urothelial cells [nTPM]":"69.6"},{"Gene":"GPD1","Gene synonym":[],"Ensembl":"ENSG00000167588","Gene description":"Glycerol-3-phosphate dehydrogenase 1","Uniprot":["P21695"],"Chromosome":"12","Position":"50103982-50111313","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"609.9","skeletal muscle":"577.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hepatocytes":"99.1","Proximal enterocytes":"247.0","Proximal tubular cells":"298.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"18.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"ASC diff":"134.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044620","HPA058621"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4700000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044620":"AB_10796803","HPA058621":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Tissue RNA - adipose tissue [nTPM]":"609.9","Tissue RNA - adrenal gland [nTPM]":"4.7","Tissue RNA - amygdala [nTPM]":"9.1","Tissue RNA - appendix [nTPM]":"1.6","Tissue RNA - basal ganglia [nTPM]":"16.8","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"229.2","Tissue RNA - cerebellum [nTPM]":"22.7","Tissue RNA - cerebral cortex [nTPM]":"12.8","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"5.5","Tissue RNA - colon [nTPM]":"6.4","Tissue RNA - duodenum [nTPM]":"76.4","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"5.3","Tissue RNA - esophagus [nTPM]":"4.9","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"16.6","Tissue RNA - heart muscle [nTPM]":"9.2","Tissue RNA - hippocampal formation [nTPM]":"10.1","Tissue RNA - hypothalamus [nTPM]":"14.2","Tissue RNA - kidney [nTPM]":"149.3","Tissue RNA - liver [nTPM]":"147.6","Tissue RNA - lung [nTPM]":"18.4","Tissue RNA - lymph node [nTPM]":"1.0","Tissue RNA - medulla oblongata [nTPM]":"32.6","Tissue RNA - midbrain [nTPM]":"18.3","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"7.2","Tissue RNA - parathyroid gland [nTPM]":"13.0","Tissue RNA - pituitary gland [nTPM]":"1.3","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"26.5","Tissue RNA - prostate [nTPM]":"1.3","Tissue RNA - rectum [nTPM]":"3.3","Tissue RNA - retina [nTPM]":"1.0","Tissue RNA - salivary gland [nTPM]":"33.0","Tissue RNA - seminal vesicle [nTPM]":"1.3","Tissue RNA - skeletal muscle [nTPM]":"577.1","Tissue RNA - skin 1 [nTPM]":"10.2","Tissue RNA - small intestine [nTPM]":"76.9","Tissue RNA - smooth muscle [nTPM]":"1.3","Tissue RNA - spinal cord [nTPM]":"32.7","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"3.3","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"18.4","Tissue RNA - thymus [nTPM]":"1.5","Tissue RNA - thyroid gland [nTPM]":"2.7","Tissue RNA - tongue [nTPM]":"215.7","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"4.1","Tissue RNA - vagina [nTPM]":"1.0","Tissue RNA - white matter [nTPM]":"49.4","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"134.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"27.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"0.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.6","Cell RNA - Hep G2 [nTPM]":"25.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"3.7","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"30.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"1.5","Cell RNA - SK-MEL-30 [nTPM]":"1.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"1.8","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.6","Cell RNA - U-266\/84 [nTPM]":"0.7","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"9.1","Brain RNA - basal ganglia [nTPM]":"16.8","Brain RNA - cerebellum [nTPM]":"22.7","Brain RNA - cerebral cortex [nTPM]":"12.8","Brain RNA - hippocampal formation [nTPM]":"10.1","Brain RNA - hypothalamus [nTPM]":"14.2","Brain RNA - medulla oblongata [nTPM]":"32.6","Brain RNA - midbrain [nTPM]":"18.3","Brain RNA - pons [nTPM]":"26.5","Brain RNA - spinal cord [nTPM]":"32.7","Brain RNA - thalamus [nTPM]":"18.4","Brain RNA - white matter [nTPM]":"49.4","Single Cell Type RNA - Adipocytes [nTPM]":"3.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"3.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"1.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"43.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"5.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"99.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.3","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"5.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"8.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"247.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"298.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"GPD1L","Gene synonym":["KIAA0089"],"Ensembl":"ENSG00000152642","Gene description":"Glycerol-3-phosphate dehydrogenase 1 like","Uniprot":["Q8N335"],"Chromosome":"3","Position":"32105689-32168709","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Brugada syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"158.4","tongue":"253.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"154.1","Distal enterocytes":"75.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"136.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.05e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.67e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.35e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.71e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.33e-15"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-3"},"Tissue RNA - adipose tissue [nTPM]":"39.0","Tissue RNA - adrenal gland [nTPM]":"44.7","Tissue RNA - amygdala [nTPM]":"18.2","Tissue RNA - appendix [nTPM]":"8.3","Tissue RNA - basal ganglia [nTPM]":"20.1","Tissue RNA - bone marrow [nTPM]":"6.9","Tissue RNA - breast [nTPM]":"30.6","Tissue RNA - cerebellum [nTPM]":"17.2","Tissue RNA - cerebral cortex [nTPM]":"21.2","Tissue RNA - cervix [nTPM]":"22.8","Tissue RNA - choroid plexus [nTPM]":"27.1","Tissue RNA - colon [nTPM]":"40.1","Tissue RNA - duodenum [nTPM]":"26.5","Tissue RNA - endometrium 1 [nTPM]":"11.6","Tissue RNA - epididymis [nTPM]":"9.8","Tissue RNA - esophagus [nTPM]":"40.9","Tissue RNA - fallopian tube [nTPM]":"19.1","Tissue RNA - gallbladder [nTPM]":"9.2","Tissue RNA - heart muscle [nTPM]":"124.8","Tissue RNA - hippocampal formation [nTPM]":"21.2","Tissue RNA - hypothalamus [nTPM]":"20.5","Tissue RNA - kidney [nTPM]":"34.2","Tissue RNA - liver [nTPM]":"2.8","Tissue RNA - lung [nTPM]":"31.3","Tissue RNA - lymph node [nTPM]":"9.0","Tissue RNA - medulla oblongata [nTPM]":"19.2","Tissue RNA - midbrain [nTPM]":"18.6","Tissue RNA - ovary [nTPM]":"16.6","Tissue RNA - pancreas [nTPM]":"21.6","Tissue RNA - parathyroid gland [nTPM]":"32.8","Tissue RNA - pituitary gland [nTPM]":"5.9","Tissue RNA - placenta [nTPM]":"20.8","Tissue RNA - pons [nTPM]":"19.3","Tissue RNA - prostate [nTPM]":"59.9","Tissue RNA - rectum [nTPM]":"36.7","Tissue RNA - retina [nTPM]":"9.8","Tissue RNA - salivary gland [nTPM]":"22.0","Tissue RNA - seminal vesicle [nTPM]":"41.2","Tissue RNA - skeletal muscle [nTPM]":"158.4","Tissue RNA - skin 1 [nTPM]":"10.3","Tissue RNA - small intestine [nTPM]":"29.0","Tissue RNA - smooth muscle [nTPM]":"16.6","Tissue RNA - spinal cord [nTPM]":"20.5","Tissue RNA - spleen [nTPM]":"12.8","Tissue RNA - stomach 1 [nTPM]":"29.7","Tissue RNA - testis [nTPM]":"6.1","Tissue RNA - thalamus [nTPM]":"18.3","Tissue RNA - thymus [nTPM]":"6.8","Tissue RNA - thyroid gland [nTPM]":"40.3","Tissue RNA - tongue [nTPM]":"253.1","Tissue RNA - tonsil [nTPM]":"10.2","Tissue RNA - urinary bladder [nTPM]":"31.0","Tissue RNA - vagina [nTPM]":"12.9","Tissue RNA - white matter [nTPM]":"21.9","Cell RNA - A-431 [nTPM]":"11.1","Cell RNA - A549 [nTPM]":"10.0","Cell RNA - AF22 [nTPM]":"3.5","Cell RNA - AN3-CA [nTPM]":"15.3","Cell RNA - ASC diff [nTPM]":"49.3","Cell RNA - ASC TERT1 [nTPM]":"11.9","Cell RNA - BEWO [nTPM]":"136.1","Cell RNA - BJ [nTPM]":"8.8","Cell RNA - BJ hTERT+ [nTPM]":"3.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.1","Cell RNA - CACO-2 [nTPM]":"10.7","Cell RNA - CAPAN-2 [nTPM]":"5.2","Cell RNA - Daudi [nTPM]":"19.4","Cell RNA - EFO-21 [nTPM]":"13.2","Cell RNA - fHDF\/TERT166 [nTPM]":"6.2","Cell RNA - GAMG [nTPM]":"11.3","Cell RNA - HaCaT [nTPM]":"12.6","Cell RNA - HAP1 [nTPM]":"23.4","Cell RNA - HBEC3-KT [nTPM]":"9.3","Cell RNA - HBF TERT88 [nTPM]":"11.6","Cell RNA - HDLM-2 [nTPM]":"8.3","Cell RNA - HEK 293 [nTPM]":"21.4","Cell RNA - HEL [nTPM]":"11.3","Cell RNA - HeLa [nTPM]":"13.2","Cell RNA - Hep G2 [nTPM]":"16.8","Cell RNA - HHSteC [nTPM]":"12.4","Cell RNA - HL-60 [nTPM]":"29.4","Cell RNA - HMC-1 [nTPM]":"39.3","Cell RNA - HSkMC [nTPM]":"35.5","Cell RNA - hTCEpi [nTPM]":"12.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.9","Cell RNA - hTERT-HME1 [nTPM]":"12.5","Cell RNA - hTERT-RPE1 [nTPM]":"9.4","Cell RNA - HUVEC TERT2 [nTPM]":"16.3","Cell RNA - JURKAT [nTPM]":"15.7","Cell RNA - K-562 [nTPM]":"8.0","Cell RNA - Karpas-707 [nTPM]":"6.1","Cell RNA - LHCN-M2 [nTPM]":"7.3","Cell RNA - MCF7 [nTPM]":"15.1","Cell RNA - MOLT-4 [nTPM]":"12.6","Cell RNA - NB-4 [nTPM]":"11.0","Cell RNA - NTERA-2 [nTPM]":"2.1","Cell RNA - OE19 [nTPM]":"27.6","Cell RNA - PC-3 [nTPM]":"44.8","Cell RNA - REH [nTPM]":"23.1","Cell RNA - RH-30 [nTPM]":"15.7","Cell RNA - RPMI-8226 [nTPM]":"40.0","Cell RNA - RPTEC TERT1 [nTPM]":"14.6","Cell RNA - RT4 [nTPM]":"66.8","Cell RNA - SCLC-21H [nTPM]":"15.1","Cell RNA - SH-SY5Y [nTPM]":"15.0","Cell RNA - SiHa [nTPM]":"6.7","Cell RNA - SK-BR-3 [nTPM]":"61.1","Cell RNA - SK-MEL-30 [nTPM]":"25.0","Cell RNA - SuSa [nTPM]":"4.8","Cell RNA - T-47d [nTPM]":"38.7","Cell RNA - THP-1 [nTPM]":"14.1","Cell RNA - TIME [nTPM]":"8.6","Cell RNA - U-138 MG [nTPM]":"10.5","Cell RNA - U-2 OS [nTPM]":"4.9","Cell RNA - U-2197 [nTPM]":"16.3","Cell RNA - U-251 MG [nTPM]":"23.6","Cell RNA - U-266\/70 [nTPM]":"4.3","Cell RNA - U-266\/84 [nTPM]":"2.0","Cell RNA - U-698 [nTPM]":"19.3","Cell RNA - U-87 MG [nTPM]":"24.0","Cell RNA - U-937 [nTPM]":"22.3","Cell RNA - WM-115 [nTPM]":"6.0","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"2.8","Blood RNA - eosinophil [nTPM]":"5.7","Blood RNA - gdT-cell [nTPM]":"3.3","Blood RNA - intermediate monocyte [nTPM]":"3.2","Blood RNA - MAIT T-cell [nTPM]":"8.0","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"4.1","Blood RNA - memory CD8 T-cell [nTPM]":"4.0","Blood RNA - myeloid DC [nTPM]":"5.6","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.5","Blood RNA - naive CD8 T-cell [nTPM]":"3.7","Blood RNA - neutrophil [nTPM]":"1.4","Blood RNA - NK-cell [nTPM]":"7.4","Blood RNA - non-classical monocyte [nTPM]":"2.1","Blood RNA - plasmacytoid DC [nTPM]":"4.4","Blood RNA - T-reg [nTPM]":"8.8","Blood RNA - total PBMC [nTPM]":"2.8","Brain RNA - amygdala [nTPM]":"18.2","Brain RNA - basal ganglia [nTPM]":"20.1","Brain RNA - cerebellum [nTPM]":"17.2","Brain RNA - cerebral cortex [nTPM]":"21.2","Brain RNA - hippocampal formation [nTPM]":"21.2","Brain RNA - hypothalamus [nTPM]":"20.5","Brain RNA - medulla oblongata [nTPM]":"19.2","Brain RNA - midbrain [nTPM]":"18.6","Brain RNA - pons [nTPM]":"19.3","Brain RNA - spinal cord [nTPM]":"20.5","Brain RNA - thalamus [nTPM]":"18.3","Brain RNA - white matter [nTPM]":"21.9","Single Cell Type RNA - Adipocytes [nTPM]":"10.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"41.8","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"4.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"4.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"20.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"154.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"18.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"36.4","Single Cell Type RNA - dendritic cells [nTPM]":"10.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"75.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"39.2","Single Cell Type RNA - Ductal cells [nTPM]":"2.0","Single Cell Type RNA - Early spermatids [nTPM]":"8.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.4","Single Cell Type RNA - Endothelial cells [nTPM]":"10.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.8","Single Cell Type RNA - Erythroid cells [nTPM]":"6.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.1","Single Cell Type RNA - Fibroblasts [nTPM]":"10.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.2","Single Cell Type RNA - granulocytes [nTPM]":"39.3","Single Cell Type RNA - Granulosa cells [nTPM]":"9.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.0","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"23.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.3","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"6.3","Single Cell Type RNA - Langerhans cells [nTPM]":"5.7","Single Cell Type RNA - Late spermatids [nTPM]":"20.7","Single Cell Type RNA - Leydig cells [nTPM]":"5.9","Single Cell Type RNA - Macrophages [nTPM]":"4.4","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"24.4","Single Cell Type RNA - monocytes [nTPM]":"2.3","Single Cell Type RNA - Muller glia cells [nTPM]":"32.9","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.3","Single Cell Type RNA - Paneth cells [nTPM]":"21.6","Single Cell Type RNA - Peritubular cells [nTPM]":"12.8","Single Cell Type RNA - Plasma cells [nTPM]":"8.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"33.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"2.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"32.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"27.1","Single Cell Type RNA - T-cells [nTPM]":"10.4","Single Cell Type RNA - Theca cells [nTPM]":"3.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.9","Single Cell Type RNA - Urothelial cells [nTPM]":"8.5"},{"Gene":"GPHN","Gene synonym":["KIAA1385"],"Ensembl":"ENSG00000171723","Gene description":"Gephyrin","Uniprot":["Q9NQX3"],"Chromosome":"14","Position":"66507407-67181803","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Molybdenum cofactor biosynthesis"],"Molecular function":["Multifunctional enzyme","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"62.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"493.0","Excitatory neurons":"686.5","Inhibitory neurons":"866.7","Oligodendrocyte precursor cells":"576.1","Oligodendrocytes":"597.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003116","CAB004419","HPA024694"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6900","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB004419":"AB_627670","HPA003116":"AB_1078963","HPA024694":"AB_1849616"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.25e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.61e-5"},"Tissue RNA - adipose tissue [nTPM]":"13.8","Tissue RNA - adrenal gland [nTPM]":"11.1","Tissue RNA - amygdala [nTPM]":"35.5","Tissue RNA - appendix [nTPM]":"3.5","Tissue RNA - basal ganglia [nTPM]":"36.0","Tissue RNA - bone marrow [nTPM]":"2.6","Tissue RNA - breast [nTPM]":"13.4","Tissue RNA - cerebellum [nTPM]":"48.4","Tissue RNA - cerebral cortex [nTPM]":"54.1","Tissue RNA - cervix [nTPM]":"9.7","Tissue RNA - choroid plexus [nTPM]":"20.9","Tissue RNA - colon [nTPM]":"11.8","Tissue RNA - duodenum [nTPM]":"7.4","Tissue RNA - endometrium 1 [nTPM]":"9.9","Tissue RNA - epididymis [nTPM]":"11.6","Tissue RNA - esophagus [nTPM]":"12.2","Tissue RNA - fallopian tube [nTPM]":"11.1","Tissue RNA - gallbladder [nTPM]":"6.2","Tissue RNA - heart muscle [nTPM]":"17.1","Tissue RNA - hippocampal formation [nTPM]":"36.1","Tissue RNA - hypothalamus [nTPM]":"37.6","Tissue RNA - kidney [nTPM]":"25.3","Tissue RNA - liver [nTPM]":"62.4","Tissue RNA - lung [nTPM]":"9.3","Tissue RNA - lymph node [nTPM]":"3.8","Tissue RNA - medulla oblongata [nTPM]":"32.7","Tissue RNA - midbrain [nTPM]":"35.3","Tissue RNA - ovary [nTPM]":"8.9","Tissue RNA - pancreas [nTPM]":"23.9","Tissue RNA - parathyroid gland [nTPM]":"11.7","Tissue RNA - pituitary gland [nTPM]":"13.6","Tissue RNA - placenta [nTPM]":"3.6","Tissue RNA - pons [nTPM]":"32.3","Tissue RNA - prostate [nTPM]":"11.3","Tissue RNA - rectum [nTPM]":"10.1","Tissue RNA - retina [nTPM]":"23.1","Tissue RNA - salivary gland [nTPM]":"9.4","Tissue RNA - seminal vesicle [nTPM]":"6.6","Tissue RNA - skeletal muscle [nTPM]":"24.5","Tissue RNA - skin 1 [nTPM]":"15.2","Tissue RNA - small intestine [nTPM]":"9.0","Tissue RNA - smooth muscle [nTPM]":"6.2","Tissue RNA - spinal cord [nTPM]":"32.4","Tissue RNA - spleen [nTPM]":"6.7","Tissue RNA - stomach 1 [nTPM]":"14.7","Tissue RNA - testis [nTPM]":"6.2","Tissue RNA - thalamus [nTPM]":"34.6","Tissue RNA - thymus [nTPM]":"5.8","Tissue RNA - thyroid gland [nTPM]":"11.9","Tissue RNA - tongue [nTPM]":"13.8","Tissue RNA - tonsil [nTPM]":"4.3","Tissue RNA - urinary bladder [nTPM]":"11.4","Tissue RNA - vagina [nTPM]":"10.7","Tissue RNA - white matter [nTPM]":"39.5","Cell RNA - A-431 [nTPM]":"39.9","Cell RNA - A549 [nTPM]":"8.8","Cell RNA - AF22 [nTPM]":"13.7","Cell RNA - AN3-CA [nTPM]":"15.9","Cell RNA - ASC diff [nTPM]":"14.2","Cell RNA - ASC TERT1 [nTPM]":"17.5","Cell RNA - BEWO [nTPM]":"9.5","Cell RNA - BJ [nTPM]":"11.1","Cell RNA - BJ hTERT+ [nTPM]":"5.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.2","Cell RNA - CACO-2 [nTPM]":"2.8","Cell RNA - CAPAN-2 [nTPM]":"17.9","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.8","Cell RNA - fHDF\/TERT166 [nTPM]":"7.7","Cell RNA - GAMG [nTPM]":"5.5","Cell RNA - HaCaT [nTPM]":"13.1","Cell RNA - HAP1 [nTPM]":"17.0","Cell RNA - HBEC3-KT [nTPM]":"19.9","Cell RNA - HBF TERT88 [nTPM]":"18.9","Cell RNA - HDLM-2 [nTPM]":"15.0","Cell RNA - HEK 293 [nTPM]":"14.9","Cell RNA - HEL [nTPM]":"15.8","Cell RNA - HeLa [nTPM]":"9.4","Cell RNA - Hep G2 [nTPM]":"22.3","Cell RNA - HHSteC [nTPM]":"7.8","Cell RNA - HL-60 [nTPM]":"9.1","Cell RNA - HMC-1 [nTPM]":"15.8","Cell RNA - HSkMC [nTPM]":"13.3","Cell RNA - hTCEpi [nTPM]":"13.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.9","Cell RNA - hTERT-HME1 [nTPM]":"16.0","Cell RNA - hTERT-RPE1 [nTPM]":"4.8","Cell RNA - HUVEC TERT2 [nTPM]":"11.8","Cell RNA - JURKAT [nTPM]":"13.8","Cell RNA - K-562 [nTPM]":"9.3","Cell RNA - Karpas-707 [nTPM]":"14.2","Cell RNA - LHCN-M2 [nTPM]":"7.1","Cell RNA - MCF7 [nTPM]":"19.2","Cell RNA - MOLT-4 [nTPM]":"11.9","Cell RNA - NB-4 [nTPM]":"22.2","Cell RNA - NTERA-2 [nTPM]":"5.0","Cell RNA - OE19 [nTPM]":"28.3","Cell RNA - PC-3 [nTPM]":"17.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"32.5","Cell RNA - RPMI-8226 [nTPM]":"13.2","Cell RNA - RPTEC TERT1 [nTPM]":"16.7","Cell RNA - RT4 [nTPM]":"7.5","Cell RNA - SCLC-21H [nTPM]":"25.8","Cell RNA - SH-SY5Y [nTPM]":"10.3","Cell RNA - SiHa [nTPM]":"10.2","Cell RNA - SK-BR-3 [nTPM]":"31.6","Cell RNA - SK-MEL-30 [nTPM]":"12.4","Cell RNA - SuSa [nTPM]":"3.3","Cell RNA - T-47d [nTPM]":"18.5","Cell RNA - THP-1 [nTPM]":"11.5","Cell RNA - TIME [nTPM]":"6.7","Cell RNA - U-138 MG [nTPM]":"14.1","Cell RNA - U-2 OS [nTPM]":"24.8","Cell RNA - U-2197 [nTPM]":"11.3","Cell RNA - U-251 MG [nTPM]":"13.0","Cell RNA - U-266\/70 [nTPM]":"22.8","Cell RNA - U-266\/84 [nTPM]":"9.1","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"10.5","Cell RNA - U-937 [nTPM]":"0.8","Cell RNA - WM-115 [nTPM]":"11.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.7","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"2.0","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"3.2","Blood RNA - memory B-cell [nTPM]":"1.2","Blood RNA - memory CD4 T-cell [nTPM]":"2.5","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"1.1","Blood RNA - naive B-cell [nTPM]":"1.9","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.6","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.3","Blood RNA - non-classical monocyte [nTPM]":"1.0","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"3.0","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"35.5","Brain RNA - basal ganglia [nTPM]":"36.0","Brain RNA - cerebellum [nTPM]":"48.4","Brain RNA - cerebral cortex [nTPM]":"54.1","Brain RNA - hippocampal formation [nTPM]":"36.1","Brain RNA - hypothalamus [nTPM]":"37.6","Brain RNA - medulla oblongata [nTPM]":"32.7","Brain RNA - midbrain [nTPM]":"35.3","Brain RNA - pons [nTPM]":"32.3","Brain RNA - spinal cord [nTPM]":"32.4","Brain RNA - thalamus [nTPM]":"34.6","Brain RNA - white matter [nTPM]":"39.5","Single Cell Type RNA - Adipocytes [nTPM]":"11.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.1","Single Cell Type RNA - Astrocytes [nTPM]":"493.0","Single Cell Type RNA - B-cells [nTPM]":"11.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"27.9","Single Cell Type RNA - Bipolar cells [nTPM]":"34.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"10.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.9","Single Cell Type RNA - dendritic cells [nTPM]":"3.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"4.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.5","Single Cell Type RNA - Endothelial cells [nTPM]":"10.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"7.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"686.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.3","Single Cell Type RNA - Fibroblasts [nTPM]":"8.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.7","Single Cell Type RNA - Hepatocytes [nTPM]":"47.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.7","Single Cell Type RNA - Horizontal cells [nTPM]":"43.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"866.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.0","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.8","Single Cell Type RNA - Langerhans cells [nTPM]":"1.7","Single Cell Type RNA - Late spermatids [nTPM]":"5.0","Single Cell Type RNA - Leydig cells [nTPM]":"11.1","Single Cell Type RNA - Macrophages [nTPM]":"4.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"148.0","Single Cell Type RNA - monocytes [nTPM]":"1.3","Single Cell Type RNA - Muller glia cells [nTPM]":"8.9","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"576.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"597.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.1","Single Cell Type RNA - Paneth cells [nTPM]":"7.8","Single Cell Type RNA - Peritubular cells [nTPM]":"5.7","Single Cell Type RNA - Plasma cells [nTPM]":"15.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"20.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"34.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.8","Single Cell Type RNA - Spermatocytes [nTPM]":"11.8","Single Cell Type RNA - Spermatogonia [nTPM]":"8.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.1","Single Cell Type RNA - T-cells [nTPM]":"7.9","Single Cell Type RNA - Theca cells [nTPM]":"9.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.4","Single Cell Type RNA - Urothelial cells [nTPM]":"6.5"},{"Gene":"GPI","Gene synonym":["AMF","NLK"],"Ensembl":"ENSG00000105220","Gene description":"Glucose-6-phosphate isomerase","Uniprot":["P06744"],"Chromosome":"19","Position":"34359480-34402413","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Gluconeogenesis","Glycolysis"],"Molecular function":["Cytokine","Growth factor","Isomerase"],"Disease involvement":["Cancer-related genes","Disease variant","Hereditary hemolytic anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"331.0","Late spermatids":"1127.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB018655","HPA024305","CAB040563","HPA052171"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"86000000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB018655":"AB_2112653","CAB040563":null,"HPA024305":"AB_1849922","HPA052171":"AB_2681748"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.52e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Tissue RNA - adipose tissue [nTPM]":"196.9","Tissue RNA - adrenal gland [nTPM]":"283.2","Tissue RNA - amygdala [nTPM]":"83.4","Tissue RNA - appendix [nTPM]":"74.5","Tissue RNA - basal ganglia [nTPM]":"101.9","Tissue RNA - bone marrow [nTPM]":"222.8","Tissue RNA - breast [nTPM]":"129.0","Tissue RNA - cerebellum [nTPM]":"67.7","Tissue RNA - cerebral cortex [nTPM]":"130.5","Tissue RNA - cervix [nTPM]":"95.0","Tissue RNA - choroid plexus [nTPM]":"84.8","Tissue RNA - colon [nTPM]":"162.9","Tissue RNA - duodenum [nTPM]":"113.7","Tissue RNA - endometrium 1 [nTPM]":"92.4","Tissue RNA - epididymis [nTPM]":"27.2","Tissue RNA - esophagus [nTPM]":"197.8","Tissue RNA - fallopian tube [nTPM]":"88.8","Tissue RNA - gallbladder [nTPM]":"87.1","Tissue RNA - heart muscle [nTPM]":"407.2","Tissue RNA - hippocampal formation [nTPM]":"108.5","Tissue RNA - hypothalamus [nTPM]":"73.6","Tissue RNA - kidney [nTPM]":"196.8","Tissue RNA - liver [nTPM]":"222.6","Tissue RNA - lung [nTPM]":"91.2","Tissue RNA - lymph node [nTPM]":"66.4","Tissue RNA - medulla oblongata [nTPM]":"73.5","Tissue RNA - midbrain [nTPM]":"58.5","Tissue RNA - ovary [nTPM]":"97.0","Tissue RNA - pancreas [nTPM]":"84.2","Tissue RNA - parathyroid gland [nTPM]":"166.3","Tissue RNA - pituitary gland [nTPM]":"147.2","Tissue RNA - placenta [nTPM]":"47.5","Tissue RNA - pons [nTPM]":"69.3","Tissue RNA - prostate [nTPM]":"94.4","Tissue RNA - rectum [nTPM]":"84.3","Tissue RNA - retina [nTPM]":"156.1","Tissue RNA - salivary gland [nTPM]":"105.1","Tissue RNA - seminal vesicle [nTPM]":"61.0","Tissue RNA - skeletal muscle [nTPM]":"416.6","Tissue RNA - skin 1 [nTPM]":"120.1","Tissue RNA - small intestine [nTPM]":"126.5","Tissue RNA - smooth muscle [nTPM]":"78.4","Tissue RNA - spinal cord [nTPM]":"34.0","Tissue RNA - spleen [nTPM]":"102.2","Tissue RNA - stomach 1 [nTPM]":"122.5","Tissue RNA - testis [nTPM]":"95.9","Tissue RNA - thalamus [nTPM]":"83.2","Tissue RNA - thymus [nTPM]":"50.1","Tissue RNA - thyroid gland [nTPM]":"100.8","Tissue RNA - tongue [nTPM]":"374.6","Tissue RNA - tonsil [nTPM]":"76.0","Tissue RNA - urinary bladder [nTPM]":"147.9","Tissue RNA - vagina [nTPM]":"121.5","Tissue RNA - white matter [nTPM]":"95.8","Cell RNA - A-431 [nTPM]":"572.9","Cell RNA - A549 [nTPM]":"596.1","Cell RNA - AF22 [nTPM]":"58.7","Cell RNA - AN3-CA [nTPM]":"433.3","Cell RNA - ASC diff [nTPM]":"167.5","Cell RNA - ASC TERT1 [nTPM]":"121.9","Cell RNA - BEWO [nTPM]":"134.1","Cell RNA - BJ [nTPM]":"183.4","Cell RNA - BJ hTERT+ [nTPM]":"132.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"206.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"253.7","Cell RNA - CACO-2 [nTPM]":"314.9","Cell RNA - CAPAN-2 [nTPM]":"169.6","Cell RNA - Daudi [nTPM]":"303.5","Cell RNA - EFO-21 [nTPM]":"311.4","Cell RNA - fHDF\/TERT166 [nTPM]":"177.9","Cell RNA - GAMG [nTPM]":"149.1","Cell RNA - HaCaT [nTPM]":"343.7","Cell RNA - HAP1 [nTPM]":"337.7","Cell RNA - HBEC3-KT [nTPM]":"437.0","Cell RNA - HBF TERT88 [nTPM]":"259.4","Cell RNA - HDLM-2 [nTPM]":"461.0","Cell RNA - HEK 293 [nTPM]":"105.1","Cell RNA - HEL [nTPM]":"382.1","Cell RNA - HeLa [nTPM]":"252.3","Cell RNA - Hep G2 [nTPM]":"310.8","Cell RNA - HHSteC [nTPM]":"108.4","Cell RNA - HL-60 [nTPM]":"517.6","Cell RNA - HMC-1 [nTPM]":"259.3","Cell RNA - HSkMC [nTPM]":"173.7","Cell RNA - hTCEpi [nTPM]":"136.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"289.0","Cell RNA - hTERT-HME1 [nTPM]":"132.7","Cell RNA - hTERT-RPE1 [nTPM]":"273.3","Cell RNA - HUVEC TERT2 [nTPM]":"209.3","Cell RNA - JURKAT [nTPM]":"230.5","Cell RNA - K-562 [nTPM]":"210.3","Cell RNA - Karpas-707 [nTPM]":"261.8","Cell RNA - LHCN-M2 [nTPM]":"140.2","Cell RNA - MCF7 [nTPM]":"319.2","Cell RNA - MOLT-4 [nTPM]":"245.5","Cell RNA - NB-4 [nTPM]":"133.5","Cell RNA - NTERA-2 [nTPM]":"158.0","Cell RNA - OE19 [nTPM]":"421.3","Cell RNA - PC-3 [nTPM]":"174.6","Cell RNA - REH [nTPM]":"242.7","Cell RNA - RH-30 [nTPM]":"149.1","Cell RNA - RPMI-8226 [nTPM]":"649.4","Cell RNA - RPTEC TERT1 [nTPM]":"254.1","Cell RNA - RT4 [nTPM]":"275.4","Cell RNA - SCLC-21H [nTPM]":"304.9","Cell RNA - SH-SY5Y [nTPM]":"185.8","Cell RNA - SiHa [nTPM]":"331.9","Cell RNA - SK-BR-3 [nTPM]":"634.3","Cell RNA - SK-MEL-30 [nTPM]":"131.7","Cell RNA - SuSa [nTPM]":"100.5","Cell RNA - T-47d [nTPM]":"144.4","Cell RNA - THP-1 [nTPM]":"161.7","Cell RNA - TIME [nTPM]":"171.9","Cell RNA - U-138 MG [nTPM]":"80.8","Cell RNA - U-2 OS [nTPM]":"185.5","Cell RNA - U-2197 [nTPM]":"256.7","Cell RNA - U-251 MG [nTPM]":"312.8","Cell RNA - U-266\/70 [nTPM]":"535.5","Cell RNA - U-266\/84 [nTPM]":"383.7","Cell RNA - U-698 [nTPM]":"318.4","Cell RNA - U-87 MG [nTPM]":"287.4","Cell RNA - U-937 [nTPM]":"372.3","Cell RNA - WM-115 [nTPM]":"170.6","Blood RNA - basophil [nTPM]":"188.8","Blood RNA - classical monocyte [nTPM]":"93.2","Blood RNA - eosinophil [nTPM]":"331.3","Blood RNA - gdT-cell [nTPM]":"80.4","Blood RNA - intermediate monocyte [nTPM]":"141.2","Blood RNA - MAIT T-cell [nTPM]":"99.1","Blood RNA - memory B-cell [nTPM]":"59.9","Blood RNA - memory CD4 T-cell [nTPM]":"73.7","Blood RNA - memory CD8 T-cell [nTPM]":"93.1","Blood RNA - myeloid DC [nTPM]":"101.0","Blood RNA - naive B-cell [nTPM]":"50.5","Blood RNA - naive CD4 T-cell [nTPM]":"61.8","Blood RNA - naive CD8 T-cell [nTPM]":"72.8","Blood RNA - neutrophil [nTPM]":"7.4","Blood RNA - NK-cell [nTPM]":"58.0","Blood RNA - non-classical monocyte [nTPM]":"180.3","Blood RNA - plasmacytoid DC [nTPM]":"31.6","Blood RNA - T-reg [nTPM]":"83.4","Blood RNA - total PBMC [nTPM]":"123.4","Brain RNA - amygdala [nTPM]":"83.4","Brain RNA - basal ganglia [nTPM]":"101.9","Brain RNA - cerebellum [nTPM]":"67.7","Brain RNA - cerebral cortex [nTPM]":"130.5","Brain RNA - hippocampal formation [nTPM]":"108.5","Brain RNA - hypothalamus [nTPM]":"73.6","Brain RNA - medulla oblongata [nTPM]":"73.5","Brain RNA - midbrain [nTPM]":"58.5","Brain RNA - pons [nTPM]":"69.3","Brain RNA - spinal cord [nTPM]":"34.0","Brain RNA - thalamus [nTPM]":"83.2","Brain RNA - white matter [nTPM]":"95.8","Single Cell Type RNA - Adipocytes [nTPM]":"34.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"40.0","Single Cell Type RNA - Astrocytes [nTPM]":"98.9","Single Cell Type RNA - B-cells [nTPM]":"43.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"25.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"30.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"104.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"42.7","Single Cell Type RNA - Bipolar cells [nTPM]":"98.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"34.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"27.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"232.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"42.9","Single Cell Type RNA - Club cells [nTPM]":"51.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"57.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"75.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"44.5","Single Cell Type RNA - dendritic cells [nTPM]":"41.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"76.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"115.4","Single Cell Type RNA - Ductal cells [nTPM]":"101.7","Single Cell Type RNA - Early spermatids [nTPM]":"331.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"35.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"41.2","Single Cell Type RNA - Endothelial cells [nTPM]":"38.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"63.7","Single Cell Type RNA - Erythroid cells [nTPM]":"46.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"121.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"66.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"69.2","Single Cell Type RNA - Fibroblasts [nTPM]":"47.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"109.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"58.0","Single Cell Type RNA - granulocytes [nTPM]":"23.4","Single Cell Type RNA - Granulosa cells [nTPM]":"36.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"42.8","Single Cell Type RNA - Hepatocytes [nTPM]":"89.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"89.6","Single Cell Type RNA - Horizontal cells [nTPM]":"237.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"127.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"75.8","Single Cell Type RNA - Ionocytes [nTPM]":"50.8","Single Cell Type RNA - Kupffer cells [nTPM]":"52.9","Single Cell Type RNA - Langerhans cells [nTPM]":"40.5","Single Cell Type RNA - Late spermatids [nTPM]":"1127.2","Single Cell Type RNA - Leydig cells [nTPM]":"37.0","Single Cell Type RNA - Macrophages [nTPM]":"58.1","Single Cell Type RNA - Melanocytes [nTPM]":"35.6","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"44.4","Single Cell Type RNA - Muller glia cells [nTPM]":"32.6","Single Cell Type RNA - NK-cells [nTPM]":"23.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"43.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"87.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"77.6","Single Cell Type RNA - Paneth cells [nTPM]":"39.4","Single Cell Type RNA - Peritubular cells [nTPM]":"30.5","Single Cell Type RNA - Plasma cells [nTPM]":"77.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"31.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"111.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"103.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"68.3","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"44.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"65.0","Single Cell Type RNA - Spermatocytes [nTPM]":"7.8","Single Cell Type RNA - Spermatogonia [nTPM]":"22.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"139.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"32.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"39.3","Single Cell Type RNA - T-cells [nTPM]":"64.3","Single Cell Type RNA - Theca cells [nTPM]":"74.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"126.9","Single Cell Type RNA - Urothelial cells [nTPM]":"37.2"},{"Gene":"GPR101","Gene synonym":[],"Ensembl":"ENSG00000165370","Gene description":"G protein-coupled receptor 101","Uniprot":["Q96P66"],"Chromosome":"X","Position":"137023929-137033995","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"143","RNA tissue specific nTPM":{"brain":"14.3"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"basal ganglia":"12.4","cerebral cortex":"4.4","hypothalamus":"14.3","thalamus":"7.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hypothalamus":"38.3"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001084"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 43: Cardiomyocytes - Nuclear processes","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA001084":"AB_1078920"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"2.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"12.4","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"4.4","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"14.3","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"1.3","Tissue RNA - midbrain [nTPM]":"0.6","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"1.5","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"1.2","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"7.6","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.1","Brain RNA - basal ganglia [nTPM]":"12.4","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"4.4","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"14.3","Brain RNA - medulla oblongata [nTPM]":"1.3","Brain RNA - midbrain [nTPM]":"0.6","Brain RNA - pons [nTPM]":"1.5","Brain RNA - spinal cord [nTPM]":"1.2","Brain RNA - thalamus [nTPM]":"7.6","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"GPR143","Gene synonym":["OA1"],"Ensembl":"ENSG00000101850","Gene description":"G protein-coupled receptor 143","Uniprot":["P51810"],"Chromosome":"X","Position":"9725346-9786297","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Albinism","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"14.2","choroid plexus":"14.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Cytotrophoblasts":"40.6","Melanocytes":"126.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"melanoma":"84.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"basophil":"3.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"granulocytes":"3.1"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"SK-MEL-30":"159.6"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003648"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA003648":"AB_2667028"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.73e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.45e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.6","Tissue RNA - adrenal gland [nTPM]":"1.1","Tissue RNA - amygdala [nTPM]":"10.6","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"13.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.7","Tissue RNA - cerebellum [nTPM]":"11.8","Tissue RNA - cerebral cortex [nTPM]":"11.5","Tissue RNA - cervix [nTPM]":"2.0","Tissue RNA - choroid plexus [nTPM]":"14.4","Tissue RNA - colon [nTPM]":"1.4","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"3.2","Tissue RNA - epididymis [nTPM]":"5.3","Tissue RNA - esophagus [nTPM]":"2.4","Tissue RNA - fallopian tube [nTPM]":"2.8","Tissue RNA - gallbladder [nTPM]":"0.9","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"10.8","Tissue RNA - hypothalamus [nTPM]":"13.1","Tissue RNA - kidney [nTPM]":"4.6","Tissue RNA - liver [nTPM]":"1.7","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"12.6","Tissue RNA - midbrain [nTPM]":"14.2","Tissue RNA - ovary [nTPM]":"3.3","Tissue RNA - pancreas [nTPM]":"1.2","Tissue RNA - parathyroid gland [nTPM]":"2.9","Tissue RNA - pituitary gland [nTPM]":"2.7","Tissue RNA - placenta [nTPM]":"6.1","Tissue RNA - pons [nTPM]":"12.3","Tissue RNA - prostate [nTPM]":"2.6","Tissue RNA - rectum [nTPM]":"1.4","Tissue RNA - retina [nTPM]":"0.9","Tissue RNA - salivary gland [nTPM]":"3.3","Tissue RNA - seminal vesicle [nTPM]":"4.4","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"8.9","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"1.0","Tissue RNA - spinal cord [nTPM]":"11.4","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.7","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"13.1","Tissue RNA - thymus [nTPM]":"1.8","Tissue RNA - thyroid gland [nTPM]":"3.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"1.6","Tissue RNA - urinary bladder [nTPM]":"1.1","Tissue RNA - vagina [nTPM]":"1.1","Tissue RNA - white matter [nTPM]":"12.2","Cell RNA - A-431 [nTPM]":"1.9","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"4.6","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"3.7","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"2.1","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"1.1","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.6","Cell RNA - HHSteC [nTPM]":"2.3","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"3.4","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"1.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"24.2","Cell RNA - HUVEC TERT2 [nTPM]":"6.7","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"12.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"11.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"22.2","Cell RNA - RT4 [nTPM]":"3.2","Cell RNA - SCLC-21H [nTPM]":"0.9","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"159.6","Cell RNA - SuSa [nTPM]":"10.8","Cell RNA - T-47d [nTPM]":"1.9","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"4.6","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"3.1","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"10.6","Brain RNA - basal ganglia [nTPM]":"13.0","Brain RNA - cerebellum [nTPM]":"11.8","Brain RNA - cerebral cortex [nTPM]":"11.5","Brain RNA - hippocampal formation [nTPM]":"10.8","Brain RNA - hypothalamus [nTPM]":"13.1","Brain RNA - medulla oblongata [nTPM]":"12.6","Brain RNA - midbrain [nTPM]":"14.2","Brain RNA - pons [nTPM]":"12.3","Brain RNA - spinal cord [nTPM]":"11.4","Brain RNA - thalamus [nTPM]":"13.1","Brain RNA - white matter [nTPM]":"12.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"9.8","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"4.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"40.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.6","Single Cell Type RNA - Endothelial cells [nTPM]":"1.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.9","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.8","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.6","Single Cell Type RNA - Late spermatids [nTPM]":"1.8","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"126.3","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.2","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.1","Single Cell Type RNA - T-cells [nTPM]":"0.7","Single Cell Type RNA - Theca cells [nTPM]":"1.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.8"},{"Gene":"GPR68","Gene synonym":["OGR1"],"Ensembl":"ENSG00000119714","Gene description":"G protein-coupled receptor 68","Uniprot":["Q15743"],"Chromosome":"14","Position":"91232532-91253925","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Amelogenesis imperfecta","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pituitary gland":"12.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"8.0","Hofbauer cells":"17.3","Langerhans cells":"22.6","NK-cells":"12.3","T-cells":"13.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"22.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"NK-cells":"20.2","T-cells":"22.9"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"fHDF\/TERT166":"9.0","U-87 MG":"28.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.06e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.31e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-3"},"Tissue RNA - adipose tissue [nTPM]":"3.7","Tissue RNA - adrenal gland [nTPM]":"1.0","Tissue RNA - amygdala [nTPM]":"2.5","Tissue RNA - appendix [nTPM]":"5.7","Tissue RNA - basal ganglia [nTPM]":"1.9","Tissue RNA - bone marrow [nTPM]":"1.4","Tissue RNA - breast [nTPM]":"2.3","Tissue RNA - cerebellum [nTPM]":"3.6","Tissue RNA - cerebral cortex [nTPM]":"4.9","Tissue RNA - cervix [nTPM]":"2.2","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"3.1","Tissue RNA - duodenum [nTPM]":"1.8","Tissue RNA - endometrium 1 [nTPM]":"1.3","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"8.7","Tissue RNA - fallopian tube [nTPM]":"1.0","Tissue RNA - gallbladder [nTPM]":"3.7","Tissue RNA - heart muscle [nTPM]":"2.4","Tissue RNA - hippocampal formation [nTPM]":"1.8","Tissue RNA - hypothalamus [nTPM]":"3.3","Tissue RNA - kidney [nTPM]":"3.1","Tissue RNA - liver [nTPM]":"1.0","Tissue RNA - lung [nTPM]":"4.9","Tissue RNA - lymph node [nTPM]":"5.9","Tissue RNA - medulla oblongata [nTPM]":"2.2","Tissue RNA - midbrain [nTPM]":"2.6","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.7","Tissue RNA - parathyroid gland [nTPM]":"0.9","Tissue RNA - pituitary gland [nTPM]":"12.2","Tissue RNA - placenta [nTPM]":"3.1","Tissue RNA - pons [nTPM]":"3.7","Tissue RNA - prostate [nTPM]":"2.7","Tissue RNA - rectum [nTPM]":"1.5","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"3.8","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"6.2","Tissue RNA - small intestine [nTPM]":"2.9","Tissue RNA - smooth muscle [nTPM]":"2.0","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"4.2","Tissue RNA - stomach 1 [nTPM]":"5.7","Tissue RNA - testis [nTPM]":"2.1","Tissue RNA - thalamus [nTPM]":"2.7","Tissue RNA - thymus [nTPM]":"1.2","Tissue RNA - thyroid gland [nTPM]":"1.7","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"2.8","Tissue RNA - urinary bladder [nTPM]":"7.5","Tissue RNA - vagina [nTPM]":"3.9","Tissue RNA - white matter [nTPM]":"1.4","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.9","Cell RNA - BEWO [nTPM]":"0.6","Cell RNA - BJ [nTPM]":"1.1","Cell RNA - BJ hTERT+ [nTPM]":"0.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"1.0","Cell RNA - Daudi [nTPM]":"0.9","Cell RNA - EFO-21 [nTPM]":"0.4","Cell RNA - fHDF\/TERT166 [nTPM]":"9.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"1.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.6","Cell RNA - HMC-1 [nTPM]":"4.1","Cell RNA - HSkMC [nTPM]":"0.4","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.8","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"4.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.4","Cell RNA - JURKAT [nTPM]":"2.9","Cell RNA - K-562 [nTPM]":"5.8","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"3.9","Cell RNA - MCF7 [nTPM]":"1.2","Cell RNA - MOLT-4 [nTPM]":"0.8","Cell RNA - NB-4 [nTPM]":"6.4","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"3.1","Cell RNA - SH-SY5Y [nTPM]":"4.4","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"1.5","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"2.8","Cell RNA - U-138 MG [nTPM]":"6.1","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"1.1","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"1.0","Cell RNA - U-266\/84 [nTPM]":"1.3","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"28.6","Cell RNA - U-937 [nTPM]":"1.1","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"22.9","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"13.8","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"5.0","Blood RNA - memory CD8 T-cell [nTPM]":"13.5","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"4.5","Blood RNA - neutrophil [nTPM]":"2.3","Blood RNA - NK-cell [nTPM]":"20.2","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"8.7","Blood RNA - total PBMC [nTPM]":"4.1","Brain RNA - amygdala [nTPM]":"2.5","Brain RNA - basal ganglia [nTPM]":"1.9","Brain RNA - cerebellum [nTPM]":"3.6","Brain RNA - cerebral cortex [nTPM]":"4.9","Brain RNA - hippocampal formation [nTPM]":"1.8","Brain RNA - hypothalamus [nTPM]":"3.3","Brain RNA - medulla oblongata [nTPM]":"2.2","Brain RNA - midbrain [nTPM]":"2.6","Brain RNA - pons [nTPM]":"3.7","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"2.7","Brain RNA - white matter [nTPM]":"1.4","Single Cell Type RNA - Adipocytes [nTPM]":"1.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"8.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"5.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"6.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"4.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"22.6","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"3.0","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"1.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.1","Single Cell Type RNA - Spermatocytes [nTPM]":"3.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"13.1","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"GPR88","Gene synonym":[],"Ensembl":"ENSG00000181656","Gene description":"G protein-coupled receptor 88","Uniprot":["Q9GZN0"],"Chromosome":"1","Position":"100538139-100542021","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"93.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"1.1","Excitatory neurons":"1.8","Hepatocytes":"2.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"liver cancer":"12.0"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"basal ganglia":"93.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"HSkMC":"1.6","SCLC-21H":"2.0"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"10","RNA mouse brain regional specific nTPM":{"basal ganglia":"718.8"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"42","RNA pig brain regional specific nTPM":{"basal ganglia":"273.1"},"Antibody":["HPA007488"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Approved","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA007488":"AB_2667844"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"4.8","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"93.9","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"7.2","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"14.4","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.9","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"3.1","Tissue RNA - hypothalamus [nTPM]":"2.6","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"8.9","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"10.1","Tissue RNA - midbrain [nTPM]":"1.4","Tissue RNA - ovary [nTPM]":"2.6","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"1.0","Tissue RNA - pituitary gland [nTPM]":"1.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"1.0","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"10.5","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"7.5","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"1.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"1.6","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"2.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.8","Brain RNA - basal ganglia [nTPM]":"93.9","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"14.4","Brain RNA - hippocampal formation [nTPM]":"3.1","Brain RNA - hypothalamus [nTPM]":"2.6","Brain RNA - medulla oblongata [nTPM]":"10.1","Brain RNA - midbrain [nTPM]":"1.4","Brain RNA - pons [nTPM]":"1.0","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"7.5","Brain RNA - white matter [nTPM]":"1.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"2.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"GPT2","Gene synonym":["ALT2"],"Ensembl":"ENSG00000166123","Gene description":"Glutamic--pyruvic transaminase 2","Uniprot":["Q8TD30"],"Chromosome":"16","Position":"46884362-46931289","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Aminotransferase","Transferase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"267.4","skeletal muscle":"176.4","tongue":"184.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"64.3","Hepatocytes":"123.9","Syncytiotrophoblasts":"83.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"1.3","naive B-cell":"1.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"159.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051514"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA051514":"AB_2681516"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.17e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Tissue RNA - adipose tissue [nTPM]":"56.8","Tissue RNA - adrenal gland [nTPM]":"10.4","Tissue RNA - amygdala [nTPM]":"51.6","Tissue RNA - appendix [nTPM]":"4.0","Tissue RNA - basal ganglia [nTPM]":"49.9","Tissue RNA - bone marrow [nTPM]":"3.8","Tissue RNA - breast [nTPM]":"17.0","Tissue RNA - cerebellum [nTPM]":"49.1","Tissue RNA - cerebral cortex [nTPM]":"56.9","Tissue RNA - cervix [nTPM]":"5.2","Tissue RNA - choroid plexus [nTPM]":"38.4","Tissue RNA - colon [nTPM]":"7.7","Tissue RNA - duodenum [nTPM]":"1.7","Tissue RNA - endometrium 1 [nTPM]":"3.7","Tissue RNA - epididymis [nTPM]":"31.4","Tissue RNA - esophagus [nTPM]":"77.8","Tissue RNA - fallopian tube [nTPM]":"7.6","Tissue RNA - gallbladder [nTPM]":"9.8","Tissue RNA - heart muscle [nTPM]":"7.9","Tissue RNA - hippocampal formation [nTPM]":"51.3","Tissue RNA - hypothalamus [nTPM]":"45.7","Tissue RNA - kidney [nTPM]":"23.5","Tissue RNA - liver [nTPM]":"103.7","Tissue RNA - lung [nTPM]":"2.1","Tissue RNA - lymph node [nTPM]":"4.3","Tissue RNA - medulla oblongata [nTPM]":"69.8","Tissue RNA - midbrain [nTPM]":"45.9","Tissue RNA - ovary [nTPM]":"2.3","Tissue RNA - pancreas [nTPM]":"267.4","Tissue RNA - parathyroid gland [nTPM]":"8.3","Tissue RNA - pituitary gland [nTPM]":"13.0","Tissue RNA - placenta [nTPM]":"3.1","Tissue RNA - pons [nTPM]":"63.9","Tissue RNA - prostate [nTPM]":"24.2","Tissue RNA - rectum [nTPM]":"4.9","Tissue RNA - retina [nTPM]":"6.9","Tissue RNA - salivary gland [nTPM]":"48.8","Tissue RNA - seminal vesicle [nTPM]":"10.9","Tissue RNA - skeletal muscle [nTPM]":"176.4","Tissue RNA - skin 1 [nTPM]":"37.8","Tissue RNA - small intestine [nTPM]":"3.9","Tissue RNA - smooth muscle [nTPM]":"3.1","Tissue RNA - spinal cord [nTPM]":"60.2","Tissue RNA - spleen [nTPM]":"2.3","Tissue RNA - stomach 1 [nTPM]":"58.6","Tissue RNA - testis [nTPM]":"15.0","Tissue RNA - thalamus [nTPM]":"54.9","Tissue RNA - thymus [nTPM]":"7.7","Tissue RNA - thyroid gland [nTPM]":"7.6","Tissue RNA - tongue [nTPM]":"184.5","Tissue RNA - tonsil [nTPM]":"13.4","Tissue RNA - urinary bladder [nTPM]":"2.7","Tissue RNA - vagina [nTPM]":"7.7","Tissue RNA - white matter [nTPM]":"64.5","Cell RNA - A-431 [nTPM]":"42.6","Cell RNA - A549 [nTPM]":"19.0","Cell RNA - AF22 [nTPM]":"23.8","Cell RNA - AN3-CA [nTPM]":"90.6","Cell RNA - ASC diff [nTPM]":"32.7","Cell RNA - ASC TERT1 [nTPM]":"7.0","Cell RNA - BEWO [nTPM]":"43.1","Cell RNA - BJ [nTPM]":"28.9","Cell RNA - BJ hTERT+ [nTPM]":"10.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"30.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.2","Cell RNA - CACO-2 [nTPM]":"65.3","Cell RNA - CAPAN-2 [nTPM]":"17.6","Cell RNA - Daudi [nTPM]":"29.9","Cell RNA - EFO-21 [nTPM]":"24.7","Cell RNA - fHDF\/TERT166 [nTPM]":"20.7","Cell RNA - GAMG [nTPM]":"15.6","Cell RNA - HaCaT [nTPM]":"33.6","Cell RNA - HAP1 [nTPM]":"43.3","Cell RNA - HBEC3-KT [nTPM]":"42.8","Cell RNA - HBF TERT88 [nTPM]":"20.4","Cell RNA - HDLM-2 [nTPM]":"14.0","Cell RNA - HEK 293 [nTPM]":"21.1","Cell RNA - HEL [nTPM]":"10.5","Cell RNA - HeLa [nTPM]":"10.8","Cell RNA - Hep G2 [nTPM]":"159.9","Cell RNA - HHSteC [nTPM]":"22.4","Cell RNA - HL-60 [nTPM]":"75.6","Cell RNA - HMC-1 [nTPM]":"9.5","Cell RNA - HSkMC [nTPM]":"15.2","Cell RNA - hTCEpi [nTPM]":"37.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"30.0","Cell RNA - hTERT-HME1 [nTPM]":"46.3","Cell RNA - hTERT-RPE1 [nTPM]":"20.3","Cell RNA - HUVEC TERT2 [nTPM]":"15.1","Cell RNA - JURKAT [nTPM]":"56.1","Cell RNA - K-562 [nTPM]":"8.7","Cell RNA - Karpas-707 [nTPM]":"23.3","Cell RNA - LHCN-M2 [nTPM]":"10.3","Cell RNA - MCF7 [nTPM]":"75.8","Cell RNA - MOLT-4 [nTPM]":"15.1","Cell RNA - NB-4 [nTPM]":"62.9","Cell RNA - NTERA-2 [nTPM]":"25.3","Cell RNA - OE19 [nTPM]":"52.2","Cell RNA - PC-3 [nTPM]":"54.2","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"26.3","Cell RNA - RPMI-8226 [nTPM]":"71.1","Cell RNA - RPTEC TERT1 [nTPM]":"12.4","Cell RNA - RT4 [nTPM]":"21.0","Cell RNA - SCLC-21H [nTPM]":"73.7","Cell RNA - SH-SY5Y [nTPM]":"37.7","Cell RNA - SiHa [nTPM]":"14.9","Cell RNA - SK-BR-3 [nTPM]":"76.4","Cell RNA - SK-MEL-30 [nTPM]":"39.0","Cell RNA - SuSa [nTPM]":"9.4","Cell RNA - T-47d [nTPM]":"19.6","Cell RNA - THP-1 [nTPM]":"67.6","Cell RNA - TIME [nTPM]":"11.3","Cell RNA - U-138 MG [nTPM]":"21.1","Cell RNA - U-2 OS [nTPM]":"40.9","Cell RNA - U-2197 [nTPM]":"14.2","Cell RNA - U-251 MG [nTPM]":"23.4","Cell RNA - U-266\/70 [nTPM]":"110.2","Cell RNA - U-266\/84 [nTPM]":"36.9","Cell RNA - U-698 [nTPM]":"87.1","Cell RNA - U-87 MG [nTPM]":"32.6","Cell RNA - U-937 [nTPM]":"48.3","Cell RNA - WM-115 [nTPM]":"11.7","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"51.6","Brain RNA - basal ganglia [nTPM]":"49.9","Brain RNA - cerebellum [nTPM]":"49.1","Brain RNA - cerebral cortex [nTPM]":"56.9","Brain RNA - hippocampal formation [nTPM]":"51.3","Brain RNA - hypothalamus [nTPM]":"45.7","Brain RNA - medulla oblongata [nTPM]":"69.8","Brain RNA - midbrain [nTPM]":"45.9","Brain RNA - pons [nTPM]":"63.9","Brain RNA - spinal cord [nTPM]":"60.2","Brain RNA - thalamus [nTPM]":"54.9","Brain RNA - white matter [nTPM]":"64.5","Single Cell Type RNA - Adipocytes [nTPM]":"1.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.4","Single Cell Type RNA - Astrocytes [nTPM]":"54.9","Single Cell Type RNA - B-cells [nTPM]":"4.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"64.3","Single Cell Type RNA - Bipolar cells [nTPM]":"14.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"9.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"7.0","Single Cell Type RNA - Early spermatids [nTPM]":"9.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.2","Single Cell Type RNA - Endothelial cells [nTPM]":"2.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"44.8","Single Cell Type RNA - Fibroblasts [nTPM]":"7.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"37.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"37.5","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"14.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"123.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.8","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.4","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"3.2","Single Cell Type RNA - Langerhans cells [nTPM]":"7.3","Single Cell Type RNA - Late spermatids [nTPM]":"22.9","Single Cell Type RNA - Leydig cells [nTPM]":"4.7","Single Cell Type RNA - Macrophages [nTPM]":"2.3","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"1.1","Single Cell Type RNA - Muller glia cells [nTPM]":"42.5","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"26.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"25.6","Single Cell Type RNA - Paneth cells [nTPM]":"5.2","Single Cell Type RNA - Peritubular cells [nTPM]":"15.4","Single Cell Type RNA - Plasma cells [nTPM]":"7.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"38.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.6","Single Cell Type RNA - Spermatocytes [nTPM]":"2.5","Single Cell Type RNA - Spermatogonia [nTPM]":"17.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"53.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"83.3","Single Cell Type RNA - T-cells [nTPM]":"1.4","Single Cell Type RNA - Theca cells [nTPM]":"2.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.3","Single Cell Type RNA - Urothelial cells [nTPM]":"4.2"},{"Gene":"GPX4","Gene synonym":["MCSP","PHGPx"],"Ensembl":"ENSG00000167468","Gene description":"Glutathione peroxidase 4","Uniprot":["P36969"],"Chromosome":"19","Position":"1103926-1106791","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Developmental protein","Oxidoreductase","Peroxidase"],"Disease involvement":["Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"18580.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB008630","HPA047224","HPA058546"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"150000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB008630":"AB_1616685","HPA047224":"AB_2679990","HPA058546":"AB_2683749"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.18e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.84e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.72e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.61e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Tissue RNA - adipose tissue [nTPM]":"927.8","Tissue RNA - adrenal gland [nTPM]":"535.3","Tissue RNA - amygdala [nTPM]":"415.1","Tissue RNA - appendix [nTPM]":"127.4","Tissue RNA - basal ganglia [nTPM]":"428.7","Tissue RNA - bone marrow [nTPM]":"178.0","Tissue RNA - breast [nTPM]":"733.3","Tissue RNA - cerebellum [nTPM]":"440.7","Tissue RNA - cerebral cortex [nTPM]":"519.1","Tissue RNA - cervix [nTPM]":"280.8","Tissue RNA - choroid plexus [nTPM]":"478.7","Tissue RNA - colon [nTPM]":"249.0","Tissue RNA - duodenum [nTPM]":"259.0","Tissue RNA - endometrium 1 [nTPM]":"188.4","Tissue RNA - epididymis [nTPM]":"318.9","Tissue RNA - esophagus [nTPM]":"220.4","Tissue RNA - fallopian tube [nTPM]":"199.2","Tissue RNA - gallbladder [nTPM]":"196.6","Tissue RNA - heart muscle [nTPM]":"426.0","Tissue RNA - hippocampal formation [nTPM]":"419.2","Tissue RNA - hypothalamus [nTPM]":"450.3","Tissue RNA - kidney [nTPM]":"536.5","Tissue RNA - liver [nTPM]":"687.8","Tissue RNA - lung [nTPM]":"307.9","Tissue RNA - lymph node [nTPM]":"216.4","Tissue RNA - medulla oblongata [nTPM]":"430.9","Tissue RNA - midbrain [nTPM]":"448.3","Tissue RNA - ovary [nTPM]":"260.3","Tissue RNA - pancreas [nTPM]":"157.9","Tissue RNA - parathyroid gland [nTPM]":"285.5","Tissue RNA - pituitary gland [nTPM]":"398.4","Tissue RNA - placenta [nTPM]":"147.2","Tissue RNA - pons [nTPM]":"454.1","Tissue RNA - prostate [nTPM]":"322.1","Tissue RNA - rectum [nTPM]":"110.9","Tissue RNA - retina [nTPM]":"167.5","Tissue RNA - salivary gland [nTPM]":"304.9","Tissue RNA - seminal vesicle [nTPM]":"193.8","Tissue RNA - skeletal muscle [nTPM]":"672.3","Tissue RNA - skin 1 [nTPM]":"290.4","Tissue RNA - small intestine [nTPM]":"236.2","Tissue RNA - smooth muscle [nTPM]":"87.9","Tissue RNA - spinal cord [nTPM]":"418.2","Tissue RNA - spleen [nTPM]":"213.2","Tissue RNA - stomach 1 [nTPM]":"219.0","Tissue RNA - testis [nTPM]":"1403.5","Tissue RNA - thalamus [nTPM]":"444.0","Tissue RNA - thymus [nTPM]":"158.7","Tissue RNA - thyroid gland [nTPM]":"291.5","Tissue RNA - tongue [nTPM]":"399.7","Tissue RNA - tonsil [nTPM]":"182.5","Tissue RNA - urinary bladder [nTPM]":"319.0","Tissue RNA - vagina [nTPM]":"245.2","Tissue RNA - white matter [nTPM]":"429.1","Cell RNA - A-431 [nTPM]":"258.1","Cell RNA - A549 [nTPM]":"286.8","Cell RNA - AF22 [nTPM]":"405.8","Cell RNA - AN3-CA [nTPM]":"863.0","Cell RNA - ASC diff [nTPM]":"1202.1","Cell RNA - ASC TERT1 [nTPM]":"706.0","Cell RNA - BEWO [nTPM]":"449.3","Cell RNA - BJ [nTPM]":"199.3","Cell RNA - BJ hTERT+ [nTPM]":"713.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"371.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"375.9","Cell RNA - CACO-2 [nTPM]":"590.5","Cell RNA - CAPAN-2 [nTPM]":"339.8","Cell RNA - Daudi [nTPM]":"92.8","Cell RNA - EFO-21 [nTPM]":"211.8","Cell RNA - fHDF\/TERT166 [nTPM]":"405.8","Cell RNA - GAMG [nTPM]":"313.5","Cell RNA - HaCaT [nTPM]":"283.1","Cell RNA - HAP1 [nTPM]":"239.7","Cell RNA - HBEC3-KT [nTPM]":"289.3","Cell RNA - HBF TERT88 [nTPM]":"180.5","Cell RNA - HDLM-2 [nTPM]":"522.3","Cell RNA - HEK 293 [nTPM]":"436.5","Cell RNA - HEL [nTPM]":"175.0","Cell RNA - HeLa [nTPM]":"246.9","Cell RNA - Hep G2 [nTPM]":"849.2","Cell RNA - HHSteC [nTPM]":"697.4","Cell RNA - HL-60 [nTPM]":"207.6","Cell RNA - HMC-1 [nTPM]":"269.4","Cell RNA - HSkMC [nTPM]":"707.3","Cell RNA - hTCEpi [nTPM]":"432.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"188.3","Cell RNA - hTERT-HME1 [nTPM]":"314.7","Cell RNA - hTERT-RPE1 [nTPM]":"665.9","Cell RNA - HUVEC TERT2 [nTPM]":"527.1","Cell RNA - JURKAT [nTPM]":"317.5","Cell RNA - K-562 [nTPM]":"249.4","Cell RNA - Karpas-707 [nTPM]":"225.7","Cell RNA - LHCN-M2 [nTPM]":"311.1","Cell RNA - MCF7 [nTPM]":"660.4","Cell RNA - MOLT-4 [nTPM]":"353.8","Cell RNA - NB-4 [nTPM]":"354.9","Cell RNA - NTERA-2 [nTPM]":"386.2","Cell RNA - OE19 [nTPM]":"569.7","Cell RNA - PC-3 [nTPM]":"458.9","Cell RNA - REH [nTPM]":"482.8","Cell RNA - RH-30 [nTPM]":"55.3","Cell RNA - RPMI-8226 [nTPM]":"271.3","Cell RNA - RPTEC TERT1 [nTPM]":"408.9","Cell RNA - RT4 [nTPM]":"629.9","Cell RNA - SCLC-21H [nTPM]":"348.3","Cell RNA - SH-SY5Y [nTPM]":"220.6","Cell RNA - SiHa [nTPM]":"390.5","Cell RNA - SK-BR-3 [nTPM]":"366.1","Cell RNA - SK-MEL-30 [nTPM]":"422.1","Cell RNA - SuSa [nTPM]":"246.7","Cell RNA - T-47d [nTPM]":"358.1","Cell RNA - THP-1 [nTPM]":"498.0","Cell RNA - TIME [nTPM]":"450.9","Cell RNA - U-138 MG [nTPM]":"392.3","Cell RNA - U-2 OS [nTPM]":"257.4","Cell RNA - U-2197 [nTPM]":"680.6","Cell RNA - U-251 MG [nTPM]":"254.6","Cell RNA - U-266\/70 [nTPM]":"786.5","Cell RNA - U-266\/84 [nTPM]":"582.0","Cell RNA - U-698 [nTPM]":"224.3","Cell RNA - U-87 MG [nTPM]":"369.4","Cell RNA - U-937 [nTPM]":"412.2","Cell RNA - WM-115 [nTPM]":"230.9","Blood RNA - basophil [nTPM]":"578.9","Blood RNA - classical monocyte [nTPM]":"539.6","Blood RNA - eosinophil [nTPM]":"564.4","Blood RNA - gdT-cell [nTPM]":"219.8","Blood RNA - intermediate monocyte [nTPM]":"405.4","Blood RNA - MAIT T-cell [nTPM]":"256.9","Blood RNA - memory B-cell [nTPM]":"352.7","Blood RNA - memory CD4 T-cell [nTPM]":"319.7","Blood RNA - memory CD8 T-cell [nTPM]":"230.7","Blood RNA - myeloid DC [nTPM]":"404.0","Blood RNA - naive B-cell [nTPM]":"309.9","Blood RNA - naive CD4 T-cell [nTPM]":"339.4","Blood RNA - naive CD8 T-cell [nTPM]":"245.0","Blood RNA - neutrophil [nTPM]":"265.1","Blood RNA - NK-cell [nTPM]":"196.6","Blood RNA - non-classical monocyte [nTPM]":"462.2","Blood RNA - plasmacytoid DC [nTPM]":"278.8","Blood RNA - T-reg [nTPM]":"310.3","Blood RNA - total PBMC [nTPM]":"841.7","Brain RNA - amygdala [nTPM]":"415.1","Brain RNA - basal ganglia [nTPM]":"428.7","Brain RNA - cerebellum [nTPM]":"440.7","Brain RNA - cerebral cortex [nTPM]":"519.1","Brain RNA - hippocampal formation [nTPM]":"419.2","Brain RNA - hypothalamus [nTPM]":"450.3","Brain RNA - medulla oblongata [nTPM]":"430.9","Brain RNA - midbrain [nTPM]":"448.3","Brain RNA - pons [nTPM]":"454.1","Brain RNA - spinal cord [nTPM]":"418.2","Brain RNA - thalamus [nTPM]":"444.0","Brain RNA - white matter [nTPM]":"429.1","Single Cell Type RNA - Adipocytes [nTPM]":"415.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"179.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"189.7","Single Cell Type RNA - Astrocytes [nTPM]":"21.2","Single Cell Type RNA - B-cells [nTPM]":"281.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"510.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"525.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1188.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"512.2","Single Cell Type RNA - Bipolar cells [nTPM]":"332.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"845.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"868.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"264.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"316.0","Single Cell Type RNA - Club cells [nTPM]":"600.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"472.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"98.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"562.5","Single Cell Type RNA - dendritic cells [nTPM]":"231.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"479.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1592.6","Single Cell Type RNA - Ductal cells [nTPM]":"515.8","Single Cell Type RNA - Early spermatids [nTPM]":"4209.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"546.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"326.3","Single Cell Type RNA - Endothelial cells [nTPM]":"268.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"397.1","Single Cell Type RNA - Erythroid cells [nTPM]":"215.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"24.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"368.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1327.3","Single Cell Type RNA - Fibroblasts [nTPM]":"536.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"99.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"442.3","Single Cell Type RNA - granulocytes [nTPM]":"346.1","Single Cell Type RNA - Granulosa cells [nTPM]":"242.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"322.0","Single Cell Type RNA - Hepatocytes [nTPM]":"826.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"1184.1","Single Cell Type RNA - Horizontal cells [nTPM]":"208.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"33.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"328.7","Single Cell Type RNA - Ionocytes [nTPM]":"671.4","Single Cell Type RNA - Kupffer cells [nTPM]":"583.1","Single Cell Type RNA - Langerhans cells [nTPM]":"1304.8","Single Cell Type RNA - Late spermatids [nTPM]":"18580.2","Single Cell Type RNA - Leydig cells [nTPM]":"384.9","Single Cell Type RNA - Macrophages [nTPM]":"735.2","Single Cell Type RNA - Melanocytes [nTPM]":"677.7","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"1786.8","Single Cell Type RNA - Muller glia cells [nTPM]":"502.6","Single Cell Type RNA - NK-cells [nTPM]":"192.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"35.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"484.0","Single Cell Type RNA - Paneth cells [nTPM]":"507.9","Single Cell Type RNA - Peritubular cells [nTPM]":"312.9","Single Cell Type RNA - Plasma cells [nTPM]":"189.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"694.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1861.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3024.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"800.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"246.0","Single Cell Type RNA - Sertoli cells [nTPM]":"243.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"244.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"587.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1310.8","Single Cell Type RNA - Spermatogonia [nTPM]":"202.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"357.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"467.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"978.1","Single Cell Type RNA - T-cells [nTPM]":"281.0","Single Cell Type RNA - Theca cells [nTPM]":"186.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"336.4","Single Cell Type RNA - Urothelial cells [nTPM]":"662.6"},{"Gene":"GPX7","Gene synonym":["FLJ14777","GPX6","NPGPx"],"Ensembl":"ENSG00000116157","Gene description":"Glutathione peroxidase 7","Uniprot":["Q96SL4"],"Chromosome":"1","Position":"52602371-52609051","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Oxidoreductase","Peroxidase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"43.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"fHDF\/TERT166":"68.6","HEL":"63.9","REH":"76.4","RPMI-8226":"130.0","THP-1":"101.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.26e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.4","Tissue RNA - adrenal gland [nTPM]":"7.9","Tissue RNA - amygdala [nTPM]":"4.8","Tissue RNA - appendix [nTPM]":"12.4","Tissue RNA - basal ganglia [nTPM]":"5.0","Tissue RNA - bone marrow [nTPM]":"18.3","Tissue RNA - breast [nTPM]":"11.9","Tissue RNA - cerebellum [nTPM]":"5.2","Tissue RNA - cerebral cortex [nTPM]":"5.4","Tissue RNA - cervix [nTPM]":"11.6","Tissue RNA - choroid plexus [nTPM]":"9.3","Tissue RNA - colon [nTPM]":"9.4","Tissue RNA - duodenum [nTPM]":"3.3","Tissue RNA - endometrium 1 [nTPM]":"13.1","Tissue RNA - epididymis [nTPM]":"7.3","Tissue RNA - esophagus [nTPM]":"4.3","Tissue RNA - fallopian tube [nTPM]":"9.1","Tissue RNA - gallbladder [nTPM]":"13.4","Tissue RNA - heart muscle [nTPM]":"10.8","Tissue RNA - hippocampal formation [nTPM]":"4.6","Tissue RNA - hypothalamus [nTPM]":"5.9","Tissue RNA - kidney [nTPM]":"6.9","Tissue RNA - liver [nTPM]":"5.3","Tissue RNA - lung [nTPM]":"6.8","Tissue RNA - lymph node [nTPM]":"16.5","Tissue RNA - medulla oblongata [nTPM]":"5.2","Tissue RNA - midbrain [nTPM]":"5.1","Tissue RNA - ovary [nTPM]":"8.9","Tissue RNA - pancreas [nTPM]":"11.5","Tissue RNA - parathyroid gland [nTPM]":"8.5","Tissue RNA - pituitary gland [nTPM]":"12.5","Tissue RNA - placenta [nTPM]":"29.3","Tissue RNA - pons [nTPM]":"5.0","Tissue RNA - prostate [nTPM]":"8.7","Tissue RNA - rectum [nTPM]":"5.5","Tissue RNA - retina [nTPM]":"1.7","Tissue RNA - salivary gland [nTPM]":"5.9","Tissue RNA - seminal vesicle [nTPM]":"9.7","Tissue RNA - skeletal muscle [nTPM]":"12.1","Tissue RNA - skin 1 [nTPM]":"5.0","Tissue RNA - small intestine [nTPM]":"6.0","Tissue RNA - smooth muscle [nTPM]":"10.8","Tissue RNA - spinal cord [nTPM]":"5.0","Tissue RNA - spleen [nTPM]":"8.1","Tissue RNA - stomach 1 [nTPM]":"5.0","Tissue RNA - testis [nTPM]":"5.5","Tissue RNA - thalamus [nTPM]":"5.0","Tissue RNA - thymus [nTPM]":"15.9","Tissue RNA - thyroid gland [nTPM]":"17.1","Tissue RNA - tongue [nTPM]":"11.5","Tissue RNA - tonsil [nTPM]":"14.0","Tissue RNA - urinary bladder [nTPM]":"12.4","Tissue RNA - vagina [nTPM]":"6.9","Tissue RNA - white matter [nTPM]":"4.9","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"18.1","Cell RNA - AN3-CA [nTPM]":"33.9","Cell RNA - ASC diff [nTPM]":"6.6","Cell RNA - ASC TERT1 [nTPM]":"19.1","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"12.5","Cell RNA - BJ hTERT+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.3","Cell RNA - CACO-2 [nTPM]":"12.2","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"9.8","Cell RNA - fHDF\/TERT166 [nTPM]":"68.6","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"29.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"8.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"63.9","Cell RNA - HeLa [nTPM]":"3.6","Cell RNA - Hep G2 [nTPM]":"11.3","Cell RNA - HHSteC [nTPM]":"23.9","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"44.4","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.5","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"22.9","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"28.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"3.3","Cell RNA - NB-4 [nTPM]":"33.5","Cell RNA - NTERA-2 [nTPM]":"31.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"76.4","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"130.0","Cell RNA - RPTEC TERT1 [nTPM]":"1.3","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"13.7","Cell RNA - SH-SY5Y [nTPM]":"27.0","Cell RNA - SiHa [nTPM]":"33.3","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"21.9","Cell RNA - SuSa [nTPM]":"3.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"101.1","Cell RNA - TIME [nTPM]":"1.4","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"3.7","Cell RNA - U-2197 [nTPM]":"3.8","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"47.9","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"11.3","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"1.7","Blood RNA - eosinophil [nTPM]":"5.4","Blood RNA - gdT-cell [nTPM]":"22.6","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"31.8","Blood RNA - memory B-cell [nTPM]":"32.0","Blood RNA - memory CD4 T-cell [nTPM]":"34.6","Blood RNA - memory CD8 T-cell [nTPM]":"27.1","Blood RNA - myeloid DC [nTPM]":"5.4","Blood RNA - naive B-cell [nTPM]":"35.2","Blood RNA - naive CD4 T-cell [nTPM]":"44.5","Blood RNA - naive CD8 T-cell [nTPM]":"29.0","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"31.6","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"73.7","Blood RNA - T-reg [nTPM]":"27.6","Blood RNA - total PBMC [nTPM]":"21.4","Brain RNA - amygdala [nTPM]":"4.8","Brain RNA - basal ganglia [nTPM]":"5.0","Brain RNA - cerebellum [nTPM]":"5.2","Brain RNA - cerebral cortex [nTPM]":"5.4","Brain RNA - hippocampal formation [nTPM]":"4.6","Brain RNA - hypothalamus [nTPM]":"5.9","Brain RNA - medulla oblongata [nTPM]":"5.2","Brain RNA - midbrain [nTPM]":"5.1","Brain RNA - pons [nTPM]":"5.0","Brain RNA - spinal cord [nTPM]":"5.0","Brain RNA - thalamus [nTPM]":"5.0","Brain RNA - white matter [nTPM]":"4.9","Single Cell Type RNA - Adipocytes [nTPM]":"8.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.5","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"16.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"1.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"6.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"22.8","Single Cell Type RNA - dendritic cells [nTPM]":"9.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.1","Single Cell Type RNA - Early spermatids [nTPM]":"6.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"43.7","Single Cell Type RNA - Endothelial cells [nTPM]":"12.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"6.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.8","Single Cell Type RNA - Fibroblasts [nTPM]":"30.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"25.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.4","Single Cell Type RNA - Hepatocytes [nTPM]":"3.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.3","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.2","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"6.6","Single Cell Type RNA - Leydig cells [nTPM]":"15.2","Single Cell Type RNA - Macrophages [nTPM]":"6.0","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"5.0","Single Cell Type RNA - Muller glia cells [nTPM]":"8.3","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.7","Single Cell Type RNA - Peritubular cells [nTPM]":"13.5","Single Cell Type RNA - Plasma cells [nTPM]":"25.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.5","Single Cell Type RNA - Spermatocytes [nTPM]":"10.8","Single Cell Type RNA - Spermatogonia [nTPM]":"12.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.6","Single Cell Type RNA - T-cells [nTPM]":"10.9","Single Cell Type RNA - Theca cells [nTPM]":"19.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"4.9"},{"Gene":"GRHPR","Gene synonym":["GLXR","PH2"],"Ensembl":"ENSG00000137106","Gene description":"Glyoxylate and hydroxypyruvate reductase","Uniprot":["Q9UBQ7"],"Chromosome":"9","Position":"37422666-37436990","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"652.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"864.6","Proximal tubular cells":"817.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022971","HPA078575"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2700000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA022971":"AB_1849975","HPA078575":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.00e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.39e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Tissue RNA - adipose tissue [nTPM]":"58.9","Tissue RNA - adrenal gland [nTPM]":"143.1","Tissue RNA - amygdala [nTPM]":"72.6","Tissue RNA - appendix [nTPM]":"35.5","Tissue RNA - basal ganglia [nTPM]":"83.9","Tissue RNA - bone marrow [nTPM]":"40.5","Tissue RNA - breast [nTPM]":"55.7","Tissue RNA - cerebellum [nTPM]":"84.1","Tissue RNA - cerebral cortex [nTPM]":"74.3","Tissue RNA - cervix [nTPM]":"53.0","Tissue RNA - choroid plexus [nTPM]":"76.1","Tissue RNA - colon [nTPM]":"60.5","Tissue RNA - duodenum [nTPM]":"63.5","Tissue RNA - endometrium 1 [nTPM]":"58.5","Tissue RNA - epididymis [nTPM]":"62.6","Tissue RNA - esophagus [nTPM]":"62.5","Tissue RNA - fallopian tube [nTPM]":"51.0","Tissue RNA - gallbladder [nTPM]":"36.6","Tissue RNA - heart muscle [nTPM]":"107.6","Tissue RNA - hippocampal formation [nTPM]":"69.7","Tissue RNA - hypothalamus [nTPM]":"76.4","Tissue RNA - kidney [nTPM]":"156.5","Tissue RNA - liver [nTPM]":"652.5","Tissue RNA - lung [nTPM]":"42.9","Tissue RNA - lymph node [nTPM]":"55.8","Tissue RNA - medulla oblongata [nTPM]":"76.3","Tissue RNA - midbrain [nTPM]":"76.2","Tissue RNA - ovary [nTPM]":"63.4","Tissue RNA - pancreas [nTPM]":"64.2","Tissue RNA - parathyroid gland [nTPM]":"49.1","Tissue RNA - pituitary gland [nTPM]":"35.7","Tissue RNA - placenta [nTPM]":"35.2","Tissue RNA - pons [nTPM]":"77.6","Tissue RNA - prostate [nTPM]":"50.7","Tissue RNA - rectum [nTPM]":"35.4","Tissue RNA - retina [nTPM]":"20.8","Tissue RNA - salivary gland [nTPM]":"74.8","Tissue RNA - seminal vesicle [nTPM]":"46.4","Tissue RNA - skeletal muscle [nTPM]":"168.5","Tissue RNA - skin 1 [nTPM]":"64.2","Tissue RNA - small intestine [nTPM]":"51.4","Tissue RNA - smooth muscle [nTPM]":"42.8","Tissue RNA - spinal cord [nTPM]":"75.9","Tissue RNA - spleen [nTPM]":"41.7","Tissue RNA - stomach 1 [nTPM]":"60.7","Tissue RNA - testis [nTPM]":"37.9","Tissue RNA - thalamus [nTPM]":"78.4","Tissue RNA - thymus [nTPM]":"34.7","Tissue RNA - thyroid gland [nTPM]":"43.4","Tissue RNA - tongue [nTPM]":"146.4","Tissue RNA - tonsil [nTPM]":"51.5","Tissue RNA - urinary bladder [nTPM]":"52.9","Tissue RNA - vagina [nTPM]":"51.8","Tissue RNA - white matter [nTPM]":"89.4","Cell RNA - A-431 [nTPM]":"111.7","Cell RNA - A549 [nTPM]":"157.7","Cell RNA - AF22 [nTPM]":"87.5","Cell RNA - AN3-CA [nTPM]":"81.0","Cell RNA - ASC diff [nTPM]":"80.1","Cell RNA - ASC TERT1 [nTPM]":"86.4","Cell RNA - BEWO [nTPM]":"87.7","Cell RNA - BJ [nTPM]":"86.2","Cell RNA - BJ hTERT+ [nTPM]":"114.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"115.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"125.2","Cell RNA - CACO-2 [nTPM]":"60.3","Cell RNA - CAPAN-2 [nTPM]":"47.2","Cell RNA - Daudi [nTPM]":"106.5","Cell RNA - EFO-21 [nTPM]":"50.0","Cell RNA - fHDF\/TERT166 [nTPM]":"105.3","Cell RNA - GAMG [nTPM]":"85.8","Cell RNA - HaCaT [nTPM]":"49.3","Cell RNA - HAP1 [nTPM]":"51.7","Cell RNA - HBEC3-KT [nTPM]":"113.5","Cell RNA - HBF TERT88 [nTPM]":"69.3","Cell RNA - HDLM-2 [nTPM]":"140.3","Cell RNA - HEK 293 [nTPM]":"62.8","Cell RNA - HEL [nTPM]":"61.6","Cell RNA - HeLa [nTPM]":"144.1","Cell RNA - Hep G2 [nTPM]":"107.5","Cell RNA - HHSteC [nTPM]":"124.3","Cell RNA - HL-60 [nTPM]":"58.7","Cell RNA - HMC-1 [nTPM]":"61.6","Cell RNA - HSkMC [nTPM]":"104.2","Cell RNA - hTCEpi [nTPM]":"97.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"67.6","Cell RNA - hTERT-HME1 [nTPM]":"87.4","Cell RNA - hTERT-RPE1 [nTPM]":"98.0","Cell RNA - HUVEC TERT2 [nTPM]":"102.2","Cell RNA - JURKAT [nTPM]":"67.5","Cell RNA - K-562 [nTPM]":"116.1","Cell RNA - Karpas-707 [nTPM]":"42.9","Cell RNA - LHCN-M2 [nTPM]":"104.2","Cell RNA - MCF7 [nTPM]":"85.3","Cell RNA - MOLT-4 [nTPM]":"58.9","Cell RNA - NB-4 [nTPM]":"60.8","Cell RNA - NTERA-2 [nTPM]":"53.5","Cell RNA - OE19 [nTPM]":"101.1","Cell RNA - PC-3 [nTPM]":"67.5","Cell RNA - REH [nTPM]":"55.4","Cell RNA - RH-30 [nTPM]":"62.1","Cell RNA - RPMI-8226 [nTPM]":"59.1","Cell RNA - RPTEC TERT1 [nTPM]":"155.9","Cell RNA - RT4 [nTPM]":"63.0","Cell RNA - SCLC-21H [nTPM]":"36.3","Cell RNA - SH-SY5Y [nTPM]":"64.3","Cell RNA - SiHa [nTPM]":"74.4","Cell RNA - SK-BR-3 [nTPM]":"143.8","Cell RNA - SK-MEL-30 [nTPM]":"84.1","Cell RNA - SuSa [nTPM]":"79.1","Cell RNA - T-47d [nTPM]":"80.1","Cell RNA - THP-1 [nTPM]":"75.7","Cell RNA - TIME [nTPM]":"109.7","Cell RNA - U-138 MG [nTPM]":"63.5","Cell RNA - U-2 OS [nTPM]":"100.4","Cell RNA - U-2197 [nTPM]":"44.0","Cell RNA - U-251 MG [nTPM]":"76.9","Cell RNA - U-266\/70 [nTPM]":"33.1","Cell RNA - U-266\/84 [nTPM]":"27.4","Cell RNA - U-698 [nTPM]":"70.8","Cell RNA - U-87 MG [nTPM]":"90.8","Cell RNA - U-937 [nTPM]":"33.5","Cell RNA - WM-115 [nTPM]":"95.7","Blood RNA - basophil [nTPM]":"45.0","Blood RNA - classical monocyte [nTPM]":"64.7","Blood RNA - eosinophil [nTPM]":"33.9","Blood RNA - gdT-cell [nTPM]":"39.3","Blood RNA - intermediate monocyte [nTPM]":"66.9","Blood RNA - MAIT T-cell [nTPM]":"32.7","Blood RNA - memory B-cell [nTPM]":"61.6","Blood RNA - memory CD4 T-cell [nTPM]":"40.8","Blood RNA - memory CD8 T-cell [nTPM]":"44.6","Blood RNA - myeloid DC [nTPM]":"70.3","Blood RNA - naive B-cell [nTPM]":"65.6","Blood RNA - naive CD4 T-cell [nTPM]":"39.6","Blood RNA - naive CD8 T-cell [nTPM]":"33.9","Blood RNA - neutrophil [nTPM]":"14.5","Blood RNA - NK-cell [nTPM]":"64.5","Blood RNA - non-classical monocyte [nTPM]":"56.7","Blood RNA - plasmacytoid DC [nTPM]":"63.4","Blood RNA - T-reg [nTPM]":"57.8","Blood RNA - total PBMC [nTPM]":"52.0","Brain RNA - amygdala [nTPM]":"72.6","Brain RNA - basal ganglia [nTPM]":"83.9","Brain RNA - cerebellum [nTPM]":"84.1","Brain RNA - cerebral cortex [nTPM]":"74.3","Brain RNA - hippocampal formation [nTPM]":"69.7","Brain RNA - hypothalamus [nTPM]":"76.4","Brain RNA - medulla oblongata [nTPM]":"76.3","Brain RNA - midbrain [nTPM]":"76.2","Brain RNA - pons [nTPM]":"77.6","Brain RNA - spinal cord [nTPM]":"75.9","Brain RNA - thalamus [nTPM]":"78.4","Brain RNA - white matter [nTPM]":"89.4","Single Cell Type RNA - Adipocytes [nTPM]":"50.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"57.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"30.2","Single Cell Type RNA - Astrocytes [nTPM]":"24.2","Single Cell Type RNA - B-cells [nTPM]":"37.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"43.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"52.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"87.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"41.5","Single Cell Type RNA - Bipolar cells [nTPM]":"39.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"53.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"65.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"103.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"177.3","Single Cell Type RNA - Club cells [nTPM]":"53.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"51.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"152.6","Single Cell Type RNA - dendritic cells [nTPM]":"33.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"65.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"248.4","Single Cell Type RNA - Ductal cells [nTPM]":"78.0","Single Cell Type RNA - Early spermatids [nTPM]":"14.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"38.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"65.4","Single Cell Type RNA - Endothelial cells [nTPM]":"47.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"62.2","Single Cell Type RNA - Erythroid cells [nTPM]":"54.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"89.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"93.0","Single Cell Type RNA - Fibroblasts [nTPM]":"67.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"52.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"44.8","Single Cell Type RNA - granulocytes [nTPM]":"50.1","Single Cell Type RNA - Granulosa cells [nTPM]":"93.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"67.5","Single Cell Type RNA - Hepatocytes [nTPM]":"864.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"110.8","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"79.7","Single Cell Type RNA - Ionocytes [nTPM]":"71.2","Single Cell Type RNA - Kupffer cells [nTPM]":"82.9","Single Cell Type RNA - Langerhans cells [nTPM]":"45.8","Single Cell Type RNA - Late spermatids [nTPM]":"16.0","Single Cell Type RNA - Leydig cells [nTPM]":"74.6","Single Cell Type RNA - Macrophages [nTPM]":"49.2","Single Cell Type RNA - Melanocytes [nTPM]":"80.0","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"71.1","Single Cell Type RNA - Muller glia cells [nTPM]":"102.8","Single Cell Type RNA - NK-cells [nTPM]":"33.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"44.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"73.8","Single Cell Type RNA - Paneth cells [nTPM]":"56.9","Single Cell Type RNA - Peritubular cells [nTPM]":"98.6","Single Cell Type RNA - Plasma cells [nTPM]":"30.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"46.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"135.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"817.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"36.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"29.1","Single Cell Type RNA - Sertoli cells [nTPM]":"78.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"54.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"71.8","Single Cell Type RNA - Spermatocytes [nTPM]":"22.3","Single Cell Type RNA - Spermatogonia [nTPM]":"19.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"74.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"56.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"88.9","Single Cell Type RNA - T-cells [nTPM]":"32.5","Single Cell Type RNA - Theca cells [nTPM]":"233.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"80.9","Single Cell Type RNA - Urothelial cells [nTPM]":"48.1"},{"Gene":"GRIA3","Gene synonym":["GluA3","GLUR3","GLURC","MRX94"],"Ensembl":"ENSG00000125675","Gene description":"Glutamate ionotropic receptor AMPA type subunit 3","Uniprot":["P42263"],"Chromosome":"X","Position":"123184153-123490915","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"31.6","retina":"17.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Excitatory neurons":"468.4","Horizontal cells":"198.5","Inhibitory neurons":"396.3","Oligodendrocyte precursor cells":"385.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"glioma":"10.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ":"23.8","BJ hTERT+":"34.5","fHDF\/TERT166":"45.9","U-2197":"15.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058659","HPA073344"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA058659":"AB_2683791","HPA073344":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.8","Tissue RNA - adrenal gland [nTPM]":"10.3","Tissue RNA - amygdala [nTPM]":"20.0","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"25.3","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"1.4","Tissue RNA - cerebellum [nTPM]":"1.3","Tissue RNA - cerebral cortex [nTPM]":"31.6","Tissue RNA - cervix [nTPM]":"6.7","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.7","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"2.1","Tissue RNA - epididymis [nTPM]":"3.6","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"1.5","Tissue RNA - gallbladder [nTPM]":"1.2","Tissue RNA - heart muscle [nTPM]":"2.0","Tissue RNA - hippocampal formation [nTPM]":"29.0","Tissue RNA - hypothalamus [nTPM]":"4.0","Tissue RNA - kidney [nTPM]":"2.5","Tissue RNA - liver [nTPM]":"7.7","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"1.9","Tissue RNA - midbrain [nTPM]":"3.4","Tissue RNA - ovary [nTPM]":"4.1","Tissue RNA - pancreas [nTPM]":"1.7","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.0","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"1.4","Tissue RNA - prostate [nTPM]":"1.7","Tissue RNA - rectum [nTPM]":"0.8","Tissue RNA - retina [nTPM]":"17.8","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"1.9","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"1.9","Tissue RNA - spinal cord [nTPM]":"4.5","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"2.0","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"6.4","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.8","Tissue RNA - urinary bladder [nTPM]":"0.6","Tissue RNA - vagina [nTPM]":"2.8","Tissue RNA - white matter [nTPM]":"20.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"2.2","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"23.8","Cell RNA - BJ hTERT+ [nTPM]":"34.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.9","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"45.9","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.5","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"8.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.3","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.6","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"1.5","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.8","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"6.6","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"15.1","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"6.6","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"20.0","Brain RNA - basal ganglia [nTPM]":"25.3","Brain RNA - cerebellum [nTPM]":"1.3","Brain RNA - cerebral cortex [nTPM]":"31.6","Brain RNA - hippocampal formation [nTPM]":"29.0","Brain RNA - hypothalamus [nTPM]":"4.0","Brain RNA - medulla oblongata [nTPM]":"1.9","Brain RNA - midbrain [nTPM]":"3.4","Brain RNA - pons [nTPM]":"1.4","Brain RNA - spinal cord [nTPM]":"4.5","Brain RNA - thalamus [nTPM]":"6.4","Brain RNA - white matter [nTPM]":"20.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"27.4","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"13.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.7","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"468.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"6.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"6.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"198.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"396.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"9.3","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"385.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"67.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"GRIP1","Gene synonym":[],"Ensembl":"ENSG00000155974","Gene description":"Glutamate receptor interacting protein 1","Uniprot":["Q9Y3R0"],"Chromosome":"12","Position":"66347431-67069162","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"16.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Inhibitory neurons":"2829.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"myeloid DC":"4.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"4.9"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"44.4","HaCaT":"48.7","REH":"30.7","RT4":"31.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038856"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038856":"AB_10673297"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.27e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"4.3","Tissue RNA - amygdala [nTPM]":"8.5","Tissue RNA - appendix [nTPM]":"2.7","Tissue RNA - basal ganglia [nTPM]":"6.6","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"3.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"14.2","Tissue RNA - cervix [nTPM]":"1.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"3.1","Tissue RNA - duodenum [nTPM]":"1.1","Tissue RNA - endometrium 1 [nTPM]":"3.5","Tissue RNA - epididymis [nTPM]":"4.7","Tissue RNA - esophagus [nTPM]":"7.3","Tissue RNA - fallopian tube [nTPM]":"4.2","Tissue RNA - gallbladder [nTPM]":"1.6","Tissue RNA - heart muscle [nTPM]":"2.7","Tissue RNA - hippocampal formation [nTPM]":"3.9","Tissue RNA - hypothalamus [nTPM]":"12.4","Tissue RNA - kidney [nTPM]":"3.3","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"0.8","Tissue RNA - lymph node [nTPM]":"0.7","Tissue RNA - medulla oblongata [nTPM]":"0.7","Tissue RNA - midbrain [nTPM]":"7.6","Tissue RNA - ovary [nTPM]":"1.2","Tissue RNA - pancreas [nTPM]":"2.0","Tissue RNA - parathyroid gland [nTPM]":"16.4","Tissue RNA - pituitary gland [nTPM]":"3.3","Tissue RNA - placenta [nTPM]":"8.2","Tissue RNA - pons [nTPM]":"2.2","Tissue RNA - prostate [nTPM]":"4.6","Tissue RNA - rectum [nTPM]":"1.7","Tissue RNA - retina [nTPM]":"4.8","Tissue RNA - salivary gland [nTPM]":"6.0","Tissue RNA - seminal vesicle [nTPM]":"9.3","Tissue RNA - skeletal muscle [nTPM]":"1.0","Tissue RNA - skin 1 [nTPM]":"9.8","Tissue RNA - small intestine [nTPM]":"1.9","Tissue RNA - smooth muscle [nTPM]":"2.8","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"2.6","Tissue RNA - stomach 1 [nTPM]":"0.8","Tissue RNA - testis [nTPM]":"6.2","Tissue RNA - thalamus [nTPM]":"3.0","Tissue RNA - thymus [nTPM]":"0.7","Tissue RNA - thyroid gland [nTPM]":"5.0","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"1.3","Tissue RNA - urinary bladder [nTPM]":"2.6","Tissue RNA - vagina [nTPM]":"2.0","Tissue RNA - white matter [nTPM]":"3.7","Cell RNA - A-431 [nTPM]":"11.1","Cell RNA - A549 [nTPM]":"10.1","Cell RNA - AF22 [nTPM]":"17.7","Cell RNA - AN3-CA [nTPM]":"2.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"44.4","Cell RNA - BJ [nTPM]":"3.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.5","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"3.3","Cell RNA - Daudi [nTPM]":"1.4","Cell RNA - EFO-21 [nTPM]":"4.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"9.5","Cell RNA - HaCaT [nTPM]":"48.7","Cell RNA - HAP1 [nTPM]":"4.9","Cell RNA - HBEC3-KT [nTPM]":"3.3","Cell RNA - HBF TERT88 [nTPM]":"2.4","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"12.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"1.2","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"8.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.8","Cell RNA - hTERT-RPE1 [nTPM]":"8.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"8.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"4.0","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"16.1","Cell RNA - OE19 [nTPM]":"1.4","Cell RNA - PC-3 [nTPM]":"3.6","Cell RNA - REH [nTPM]":"30.7","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"5.6","Cell RNA - RT4 [nTPM]":"31.0","Cell RNA - SCLC-21H [nTPM]":"10.8","Cell RNA - SH-SY5Y [nTPM]":"1.4","Cell RNA - SiHa [nTPM]":"14.8","Cell RNA - SK-BR-3 [nTPM]":"7.1","Cell RNA - SK-MEL-30 [nTPM]":"1.4","Cell RNA - SuSa [nTPM]":"11.3","Cell RNA - T-47d [nTPM]":"8.7","Cell RNA - THP-1 [nTPM]":"1.8","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"12.7","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"9.0","Cell RNA - U-266\/70 [nTPM]":"1.5","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"1.0","Cell RNA - U-87 MG [nTPM]":"12.0","Cell RNA - U-937 [nTPM]":"0.7","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"4.9","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"8.5","Brain RNA - basal ganglia [nTPM]":"6.6","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"14.2","Brain RNA - hippocampal formation [nTPM]":"3.9","Brain RNA - hypothalamus [nTPM]":"12.4","Brain RNA - medulla oblongata [nTPM]":"0.7","Brain RNA - midbrain [nTPM]":"7.6","Brain RNA - pons [nTPM]":"2.2","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"3.0","Brain RNA - white matter [nTPM]":"3.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"74.7","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"5.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"1.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.8","Single Cell Type RNA - dendritic cells [nTPM]":"0.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.2","Single Cell Type RNA - Early spermatids [nTPM]":"38.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"390.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.3","Single Cell Type RNA - Fibroblasts [nTPM]":"1.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.0","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2829.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.4","Single Cell Type RNA - Langerhans cells [nTPM]":"1.6","Single Cell Type RNA - Late spermatids [nTPM]":"34.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"2.1","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"158.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"44.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.6","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"1.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.7","Single Cell Type RNA - Urothelial cells [nTPM]":"3.1"},{"Gene":"GRK1","Gene synonym":["GPRK1","RHOK","RK"],"Ensembl":"ENSG00000185974","Gene description":"G protein-coupled receptor kinase 1","Uniprot":["Q15835"],"Chromosome":"13","Position":"113667219-113737736","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Congenital stationary night blindness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"50","RNA tissue specific nTPM":{"retina":"42.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"56.3","Rod photoreceptor cells":"84.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"thyroid cancer":"0.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035200","HPA059376"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035200":"AB_2674515","HPA059376":"AB_2683996"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"42.6","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.8","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"56.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"84.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"GRM1","Gene synonym":["GPRC1A","mGlu1","MGLUR1","PPP1R85"],"Ensembl":"ENSG00000152822","Gene description":"Glutamate metabotropic receptor 1","Uniprot":["Q13255"],"Chromosome":"6","Position":"146027646-146437601","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"27.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Excitatory neurons":"215.5","Inhibitory neurons":"138.8","Rod photoreceptor cells":"124.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"27.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015701"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA015701":"AB_1853917"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.48e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"3.3","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"3.6","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"27.6","Tissue RNA - cerebral cortex [nTPM]":"6.8","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"2.8","Tissue RNA - hippocampal formation [nTPM]":"7.3","Tissue RNA - hypothalamus [nTPM]":"2.3","Tissue RNA - kidney [nTPM]":"0.7","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"3.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"5.4","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"7.7","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.3","Brain RNA - basal ganglia [nTPM]":"3.6","Brain RNA - cerebellum [nTPM]":"27.6","Brain RNA - cerebral cortex [nTPM]":"6.8","Brain RNA - hippocampal formation [nTPM]":"7.3","Brain RNA - hypothalamus [nTPM]":"2.3","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"3.1","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"7.7","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"23.5","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"13.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"8.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"215.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"138.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"124.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"1.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"GRM6","Gene synonym":["CSNB1B","GPRC1F","mGlu6","MGLUR6"],"Ensembl":"ENSG00000113262","Gene description":"Glutamate metabotropic receptor 6","Uniprot":["O15303"],"Chromosome":"5","Position":"178977587-178996206","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Congenital stationary night blindness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"57","RNA tissue specific nTPM":{"retina":"42.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"31","RNA single cell type specific nTPM":{"Bipolar cells":"440.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014511"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014511":"AB_2669025"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.7","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"42.6","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"440.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.9","Single Cell Type RNA - Late spermatids [nTPM]":"1.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"4.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.9","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"GSDME","Gene synonym":["DFNA5","ICERE-1"],"Ensembl":"ENSG00000105928","Gene description":"Gasdermin E","Uniprot":["O60443"],"Chromosome":"7","Position":"24698355-24757940","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Necrosis"],"Molecular function":null,"Disease involvement":["Deafness","Non-syndromic deafness","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"168.1","Distal tubular cells":"41.1","Extravillous trophoblasts":"26.5","Hofbauer cells":"39.9","Syncytiotrophoblasts":"104.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"memory B-cell":"9.0","myeloid DC":"5.9","naive B-cell":"8.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011326","CAB019306"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB019306":null,"HPA011326":"AB_1847629"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.49e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-2"},"Tissue RNA - adipose tissue [nTPM]":"13.5","Tissue RNA - adrenal gland [nTPM]":"7.8","Tissue RNA - amygdala [nTPM]":"16.4","Tissue RNA - appendix [nTPM]":"2.9","Tissue RNA - basal ganglia [nTPM]":"16.7","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"7.6","Tissue RNA - cerebellum [nTPM]":"13.3","Tissue RNA - cerebral cortex [nTPM]":"18.0","Tissue RNA - cervix [nTPM]":"17.3","Tissue RNA - choroid plexus [nTPM]":"9.2","Tissue RNA - colon [nTPM]":"6.4","Tissue RNA - duodenum [nTPM]":"7.7","Tissue RNA - endometrium 1 [nTPM]":"24.8","Tissue RNA - epididymis [nTPM]":"15.3","Tissue RNA - esophagus [nTPM]":"3.6","Tissue RNA - fallopian tube [nTPM]":"14.3","Tissue RNA - gallbladder [nTPM]":"8.5","Tissue RNA - heart muscle [nTPM]":"9.7","Tissue RNA - hippocampal formation [nTPM]":"18.1","Tissue RNA - hypothalamus [nTPM]":"15.0","Tissue RNA - kidney [nTPM]":"13.3","Tissue RNA - liver [nTPM]":"4.5","Tissue RNA - lung [nTPM]":"4.4","Tissue RNA - lymph node [nTPM]":"5.8","Tissue RNA - medulla oblongata [nTPM]":"19.4","Tissue RNA - midbrain [nTPM]":"18.7","Tissue RNA - ovary [nTPM]":"16.9","Tissue RNA - pancreas [nTPM]":"2.6","Tissue RNA - parathyroid gland [nTPM]":"7.3","Tissue RNA - pituitary gland [nTPM]":"7.0","Tissue RNA - placenta [nTPM]":"35.0","Tissue RNA - pons [nTPM]":"16.1","Tissue RNA - prostate [nTPM]":"7.5","Tissue RNA - rectum [nTPM]":"2.4","Tissue RNA - retina [nTPM]":"6.3","Tissue RNA - salivary gland [nTPM]":"3.1","Tissue RNA - seminal vesicle [nTPM]":"21.1","Tissue RNA - skeletal muscle [nTPM]":"7.8","Tissue RNA - skin 1 [nTPM]":"3.0","Tissue RNA - small intestine [nTPM]":"26.8","Tissue RNA - smooth muscle [nTPM]":"15.1","Tissue RNA - spinal cord [nTPM]":"16.5","Tissue RNA - spleen [nTPM]":"1.8","Tissue RNA - stomach 1 [nTPM]":"3.9","Tissue RNA - testis [nTPM]":"12.9","Tissue RNA - thalamus [nTPM]":"14.1","Tissue RNA - thymus [nTPM]":"5.8","Tissue RNA - thyroid gland [nTPM]":"14.5","Tissue RNA - tongue [nTPM]":"5.2","Tissue RNA - tonsil [nTPM]":"3.8","Tissue RNA - urinary bladder [nTPM]":"15.0","Tissue RNA - vagina [nTPM]":"10.1","Tissue RNA - white matter [nTPM]":"26.6","Cell RNA - A-431 [nTPM]":"31.4","Cell RNA - A549 [nTPM]":"21.7","Cell RNA - AF22 [nTPM]":"9.6","Cell RNA - AN3-CA [nTPM]":"41.2","Cell RNA - ASC diff [nTPM]":"51.4","Cell RNA - ASC TERT1 [nTPM]":"28.6","Cell RNA - BEWO [nTPM]":"16.4","Cell RNA - BJ [nTPM]":"24.1","Cell RNA - BJ hTERT+ [nTPM]":"63.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"34.3","Cell RNA - CACO-2 [nTPM]":"22.9","Cell RNA - CAPAN-2 [nTPM]":"1.1","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"20.6","Cell RNA - fHDF\/TERT166 [nTPM]":"66.4","Cell RNA - GAMG [nTPM]":"81.7","Cell RNA - HaCaT [nTPM]":"20.5","Cell RNA - HAP1 [nTPM]":"5.8","Cell RNA - HBEC3-KT [nTPM]":"105.4","Cell RNA - HBF TERT88 [nTPM]":"42.8","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"2.1","Cell RNA - HEL [nTPM]":"0.8","Cell RNA - HeLa [nTPM]":"39.3","Cell RNA - Hep G2 [nTPM]":"48.0","Cell RNA - HHSteC [nTPM]":"43.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"1.5","Cell RNA - HSkMC [nTPM]":"31.3","Cell RNA - hTCEpi [nTPM]":"75.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"43.5","Cell RNA - hTERT-HME1 [nTPM]":"103.1","Cell RNA - hTERT-RPE1 [nTPM]":"73.0","Cell RNA - HUVEC TERT2 [nTPM]":"42.3","Cell RNA - JURKAT [nTPM]":"13.8","Cell RNA - K-562 [nTPM]":"3.0","Cell RNA - Karpas-707 [nTPM]":"5.2","Cell RNA - LHCN-M2 [nTPM]":"55.3","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"1.9","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"10.2","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"15.7","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"33.6","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"74.5","Cell RNA - RT4 [nTPM]":"21.9","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"60.0","Cell RNA - SiHa [nTPM]":"36.5","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"42.3","Cell RNA - SuSa [nTPM]":"24.3","Cell RNA - T-47d [nTPM]":"2.2","Cell RNA - THP-1 [nTPM]":"2.8","Cell RNA - TIME [nTPM]":"27.9","Cell RNA - U-138 MG [nTPM]":"23.1","Cell RNA - U-2 OS [nTPM]":"39.7","Cell RNA - U-2197 [nTPM]":"31.6","Cell RNA - U-251 MG [nTPM]":"29.2","Cell RNA - U-266\/70 [nTPM]":"2.4","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"15.5","Cell RNA - U-87 MG [nTPM]":"69.8","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"5.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.9","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"9.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"5.9","Blood RNA - naive B-cell [nTPM]":"8.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"16.4","Brain RNA - basal ganglia [nTPM]":"16.7","Brain RNA - cerebellum [nTPM]":"13.3","Brain RNA - cerebral cortex [nTPM]":"18.0","Brain RNA - hippocampal formation [nTPM]":"18.1","Brain RNA - hypothalamus [nTPM]":"15.0","Brain RNA - medulla oblongata [nTPM]":"19.4","Brain RNA - midbrain [nTPM]":"18.7","Brain RNA - pons [nTPM]":"16.1","Brain RNA - spinal cord [nTPM]":"16.5","Brain RNA - thalamus [nTPM]":"14.1","Brain RNA - white matter [nTPM]":"26.6","Single Cell Type RNA - Adipocytes [nTPM]":"1.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"168.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"41.1","Single Cell Type RNA - Ductal cells [nTPM]":"1.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.9","Single Cell Type RNA - Endothelial cells [nTPM]":"1.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.5","Single Cell Type RNA - Fibroblasts [nTPM]":"4.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"4.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"39.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"6.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"8.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"104.7","Single Cell Type RNA - T-cells [nTPM]":"0.7","Single Cell Type RNA - Theca cells [nTPM]":"0.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"GSTZ1","Gene synonym":["GSTZ1-1","MAAI","MAI"],"Ensembl":"ENSG00000100577","Gene description":"Glutathione S-transferase zeta 1","Uniprot":["O43708"],"Chromosome":"14","Position":"77320996-77331597","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Phenylalanine catabolism","Tyrosine catabolism"],"Molecular function":["Isomerase","Multifunctional enzyme","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"liver":"263.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"373.2","Late spermatids":"398.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"182.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004701"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"340000","Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA004701":"AB_1078990"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.93e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.73e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.12e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-2"},"Tissue RNA - adipose tissue [nTPM]":"13.9","Tissue RNA - adrenal gland [nTPM]":"34.7","Tissue RNA - amygdala [nTPM]":"11.1","Tissue RNA - appendix [nTPM]":"9.7","Tissue RNA - basal ganglia [nTPM]":"12.5","Tissue RNA - bone marrow [nTPM]":"9.3","Tissue RNA - breast [nTPM]":"23.2","Tissue RNA - cerebellum [nTPM]":"13.2","Tissue RNA - cerebral cortex [nTPM]":"16.3","Tissue RNA - cervix [nTPM]":"12.7","Tissue RNA - choroid plexus [nTPM]":"10.5","Tissue RNA - colon [nTPM]":"21.9","Tissue RNA - duodenum [nTPM]":"22.5","Tissue RNA - endometrium 1 [nTPM]":"10.8","Tissue RNA - epididymis [nTPM]":"22.1","Tissue RNA - esophagus [nTPM]":"26.9","Tissue RNA - fallopian tube [nTPM]":"14.9","Tissue RNA - gallbladder [nTPM]":"11.9","Tissue RNA - heart muscle [nTPM]":"14.3","Tissue RNA - hippocampal formation [nTPM]":"10.5","Tissue RNA - hypothalamus [nTPM]":"12.3","Tissue RNA - kidney [nTPM]":"24.5","Tissue RNA - liver [nTPM]":"263.1","Tissue RNA - lung [nTPM]":"7.8","Tissue RNA - lymph node [nTPM]":"13.5","Tissue RNA - medulla oblongata [nTPM]":"12.6","Tissue RNA - midbrain [nTPM]":"11.7","Tissue RNA - ovary [nTPM]":"6.5","Tissue RNA - pancreas [nTPM]":"20.1","Tissue RNA - parathyroid gland [nTPM]":"26.4","Tissue RNA - pituitary gland [nTPM]":"13.3","Tissue RNA - placenta [nTPM]":"11.2","Tissue RNA - pons [nTPM]":"12.8","Tissue RNA - prostate [nTPM]":"21.1","Tissue RNA - rectum [nTPM]":"21.7","Tissue RNA - retina [nTPM]":"5.1","Tissue RNA - salivary gland [nTPM]":"24.1","Tissue RNA - seminal vesicle [nTPM]":"9.6","Tissue RNA - skeletal muscle [nTPM]":"47.4","Tissue RNA - skin 1 [nTPM]":"22.1","Tissue RNA - small intestine [nTPM]":"15.6","Tissue RNA - smooth muscle [nTPM]":"7.9","Tissue RNA - spinal cord [nTPM]":"12.3","Tissue RNA - spleen [nTPM]":"12.1","Tissue RNA - stomach 1 [nTPM]":"18.9","Tissue RNA - testis [nTPM]":"57.8","Tissue RNA - thalamus [nTPM]":"11.9","Tissue RNA - thymus [nTPM]":"14.0","Tissue RNA - thyroid gland [nTPM]":"19.5","Tissue RNA - tongue [nTPM]":"37.3","Tissue RNA - tonsil [nTPM]":"17.4","Tissue RNA - urinary bladder [nTPM]":"11.9","Tissue RNA - vagina [nTPM]":"13.8","Tissue RNA - white matter [nTPM]":"14.0","Cell RNA - A-431 [nTPM]":"18.8","Cell RNA - A549 [nTPM]":"39.0","Cell RNA - AF22 [nTPM]":"27.6","Cell RNA - AN3-CA [nTPM]":"19.9","Cell RNA - ASC diff [nTPM]":"17.1","Cell RNA - ASC TERT1 [nTPM]":"23.9","Cell RNA - BEWO [nTPM]":"45.8","Cell RNA - BJ [nTPM]":"11.4","Cell RNA - BJ hTERT+ [nTPM]":"11.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"30.9","Cell RNA - CACO-2 [nTPM]":"13.0","Cell RNA - CAPAN-2 [nTPM]":"45.2","Cell RNA - Daudi [nTPM]":"43.5","Cell RNA - EFO-21 [nTPM]":"14.9","Cell RNA - fHDF\/TERT166 [nTPM]":"13.6","Cell RNA - GAMG [nTPM]":"13.4","Cell RNA - HaCaT [nTPM]":"24.1","Cell RNA - HAP1 [nTPM]":"18.9","Cell RNA - HBEC3-KT [nTPM]":"22.5","Cell RNA - HBF TERT88 [nTPM]":"20.7","Cell RNA - HDLM-2 [nTPM]":"23.2","Cell RNA - HEK 293 [nTPM]":"21.0","Cell RNA - HEL [nTPM]":"20.8","Cell RNA - HeLa [nTPM]":"13.3","Cell RNA - Hep G2 [nTPM]":"26.9","Cell RNA - HHSteC [nTPM]":"26.3","Cell RNA - HL-60 [nTPM]":"7.8","Cell RNA - HMC-1 [nTPM]":"15.8","Cell RNA - HSkMC [nTPM]":"22.1","Cell RNA - hTCEpi [nTPM]":"24.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.4","Cell RNA - hTERT-HME1 [nTPM]":"20.8","Cell RNA - hTERT-RPE1 [nTPM]":"12.0","Cell RNA - HUVEC TERT2 [nTPM]":"18.6","Cell RNA - JURKAT [nTPM]":"24.7","Cell RNA - K-562 [nTPM]":"17.5","Cell RNA - Karpas-707 [nTPM]":"37.0","Cell RNA - LHCN-M2 [nTPM]":"14.5","Cell RNA - MCF7 [nTPM]":"182.1","Cell RNA - MOLT-4 [nTPM]":"12.2","Cell RNA - NB-4 [nTPM]":"16.4","Cell RNA - NTERA-2 [nTPM]":"8.2","Cell RNA - OE19 [nTPM]":"64.1","Cell RNA - PC-3 [nTPM]":"30.3","Cell RNA - REH [nTPM]":"20.2","Cell RNA - RH-30 [nTPM]":"29.5","Cell RNA - RPMI-8226 [nTPM]":"34.2","Cell RNA - RPTEC TERT1 [nTPM]":"32.5","Cell RNA - RT4 [nTPM]":"24.0","Cell RNA - SCLC-21H [nTPM]":"30.2","Cell RNA - SH-SY5Y [nTPM]":"26.2","Cell RNA - SiHa [nTPM]":"26.0","Cell RNA - SK-BR-3 [nTPM]":"49.1","Cell RNA - SK-MEL-30 [nTPM]":"35.6","Cell RNA - SuSa [nTPM]":"15.5","Cell RNA - T-47d [nTPM]":"81.2","Cell RNA - THP-1 [nTPM]":"11.1","Cell RNA - TIME [nTPM]":"13.8","Cell RNA - U-138 MG [nTPM]":"17.0","Cell RNA - U-2 OS [nTPM]":"52.5","Cell RNA - U-2197 [nTPM]":"18.9","Cell RNA - U-251 MG [nTPM]":"8.6","Cell RNA - U-266\/70 [nTPM]":"28.2","Cell RNA - U-266\/84 [nTPM]":"32.7","Cell RNA - U-698 [nTPM]":"35.2","Cell RNA - U-87 MG [nTPM]":"41.9","Cell RNA - U-937 [nTPM]":"11.3","Cell RNA - WM-115 [nTPM]":"20.8","Blood RNA - basophil [nTPM]":"13.4","Blood RNA - classical monocyte [nTPM]":"15.5","Blood RNA - eosinophil [nTPM]":"9.9","Blood RNA - gdT-cell [nTPM]":"2.6","Blood RNA - intermediate monocyte [nTPM]":"22.2","Blood RNA - MAIT T-cell [nTPM]":"2.4","Blood RNA - memory B-cell [nTPM]":"8.2","Blood RNA - memory CD4 T-cell [nTPM]":"4.6","Blood RNA - memory CD8 T-cell [nTPM]":"3.7","Blood RNA - myeloid DC [nTPM]":"20.7","Blood RNA - naive B-cell [nTPM]":"10.4","Blood RNA - naive CD4 T-cell [nTPM]":"3.9","Blood RNA - naive CD8 T-cell [nTPM]":"3.1","Blood RNA - neutrophil [nTPM]":"1.6","Blood RNA - NK-cell [nTPM]":"5.1","Blood RNA - non-classical monocyte [nTPM]":"20.1","Blood RNA - plasmacytoid DC [nTPM]":"15.0","Blood RNA - T-reg [nTPM]":"7.9","Blood RNA - total PBMC [nTPM]":"7.4","Brain RNA - amygdala [nTPM]":"11.1","Brain RNA - basal ganglia [nTPM]":"12.5","Brain RNA - cerebellum [nTPM]":"13.2","Brain RNA - cerebral cortex [nTPM]":"16.3","Brain RNA - hippocampal formation [nTPM]":"10.5","Brain RNA - hypothalamus [nTPM]":"12.3","Brain RNA - medulla oblongata [nTPM]":"12.6","Brain RNA - midbrain [nTPM]":"11.7","Brain RNA - pons [nTPM]":"12.8","Brain RNA - spinal cord [nTPM]":"12.3","Brain RNA - thalamus [nTPM]":"11.9","Brain RNA - white matter [nTPM]":"14.0","Single Cell Type RNA - Adipocytes [nTPM]":"6.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.6","Single Cell Type RNA - Astrocytes [nTPM]":"6.5","Single Cell Type RNA - B-cells [nTPM]":"13.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"19.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"26.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Bipolar cells [nTPM]":"7.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"36.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"34.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"47.1","Single Cell Type RNA - Club cells [nTPM]":"19.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"91.4","Single Cell Type RNA - dendritic cells [nTPM]":"7.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"34.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"46.9","Single Cell Type RNA - Ductal cells [nTPM]":"45.0","Single Cell Type RNA - Early spermatids [nTPM]":"125.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.6","Single Cell Type RNA - Endothelial cells [nTPM]":"11.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"28.8","Single Cell Type RNA - Erythroid cells [nTPM]":"30.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"68.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"62.5","Single Cell Type RNA - Fibroblasts [nTPM]":"15.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"33.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"27.0","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"25.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.4","Single Cell Type RNA - Hepatocytes [nTPM]":"373.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"44.6","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"45.7","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"38.1","Single Cell Type RNA - Langerhans cells [nTPM]":"10.9","Single Cell Type RNA - Late spermatids [nTPM]":"398.1","Single Cell Type RNA - Leydig cells [nTPM]":"11.8","Single Cell Type RNA - Macrophages [nTPM]":"19.0","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"30.4","Single Cell Type RNA - Muller glia cells [nTPM]":"26.4","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"41.8","Single Cell Type RNA - Paneth cells [nTPM]":"37.4","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"13.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"72.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"77.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.2","Single Cell Type RNA - Spermatocytes [nTPM]":"51.3","Single Cell Type RNA - Spermatogonia [nTPM]":"29.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"38.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"76.2","Single Cell Type RNA - T-cells [nTPM]":"6.7","Single Cell Type RNA - Theca cells [nTPM]":"55.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"50.3","Single Cell Type RNA - Urothelial cells [nTPM]":"30.3"},{"Gene":"GUCA1B","Gene synonym":["GCAP2","RP48"],"Ensembl":"ENSG00000112599","Gene description":"Guanylate cyclase activator 1B","Uniprot":["Q9UMX6"],"Chromosome":"6","Position":"42183284-42194956","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"99","RNA tissue specific nTPM":{"retina":"466.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"23.2","Cone photoreceptor cells":"83.4","Oligodendrocytes":"28.2","Rod photoreceptor cells":"53.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTCEpi":"4.3","U-698":"3.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055479"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA055479":"AB_2732598"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-6"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-3"},"Tissue RNA - adipose tissue [nTPM]":"1.5","Tissue RNA - adrenal gland [nTPM]":"0.9","Tissue RNA - amygdala [nTPM]":"3.5","Tissue RNA - appendix [nTPM]":"0.8","Tissue RNA - basal ganglia [nTPM]":"3.6","Tissue RNA - bone marrow [nTPM]":"1.3","Tissue RNA - breast [nTPM]":"1.4","Tissue RNA - cerebellum [nTPM]":"3.8","Tissue RNA - cerebral cortex [nTPM]":"4.1","Tissue RNA - cervix [nTPM]":"2.3","Tissue RNA - choroid plexus [nTPM]":"2.2","Tissue RNA - colon [nTPM]":"1.3","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"1.9","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"0.8","Tissue RNA - fallopian tube [nTPM]":"2.3","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"1.6","Tissue RNA - hippocampal formation [nTPM]":"3.2","Tissue RNA - hypothalamus [nTPM]":"3.2","Tissue RNA - kidney [nTPM]":"1.0","Tissue RNA - liver [nTPM]":"1.9","Tissue RNA - lung [nTPM]":"1.1","Tissue RNA - lymph node [nTPM]":"0.7","Tissue RNA - medulla oblongata [nTPM]":"3.3","Tissue RNA - midbrain [nTPM]":"3.2","Tissue RNA - ovary [nTPM]":"2.7","Tissue RNA - pancreas [nTPM]":"0.9","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"1.0","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"3.6","Tissue RNA - prostate [nTPM]":"1.5","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"466.0","Tissue RNA - salivary gland [nTPM]":"1.1","Tissue RNA - seminal vesicle [nTPM]":"0.5","Tissue RNA - skeletal muscle [nTPM]":"2.6","Tissue RNA - skin 1 [nTPM]":"2.8","Tissue RNA - small intestine [nTPM]":"1.4","Tissue RNA - smooth muscle [nTPM]":"1.0","Tissue RNA - spinal cord [nTPM]":"3.0","Tissue RNA - spleen [nTPM]":"2.1","Tissue RNA - stomach 1 [nTPM]":"0.8","Tissue RNA - testis [nTPM]":"2.6","Tissue RNA - thalamus [nTPM]":"3.5","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"1.0","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"0.9","Tissue RNA - urinary bladder [nTPM]":"1.1","Tissue RNA - vagina [nTPM]":"1.4","Tissue RNA - white matter [nTPM]":"4.6","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.6","Cell RNA - AF22 [nTPM]":"1.3","Cell RNA - AN3-CA [nTPM]":"0.5","Cell RNA - ASC diff [nTPM]":"1.0","Cell RNA - ASC TERT1 [nTPM]":"0.9","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.5","Cell RNA - BJ hTERT+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.7","Cell RNA - CACO-2 [nTPM]":"1.1","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"1.6","Cell RNA - EFO-21 [nTPM]":"0.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"1.4","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"1.4","Cell RNA - HDLM-2 [nTPM]":"1.3","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"1.5","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"4.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.8","Cell RNA - hTERT-HME1 [nTPM]":"1.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"1.2","Cell RNA - K-562 [nTPM]":"1.0","Cell RNA - Karpas-707 [nTPM]":"1.5","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"1.3","Cell RNA - MOLT-4 [nTPM]":"0.6","Cell RNA - NB-4 [nTPM]":"1.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.8","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.8","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"0.9","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.9","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"1.7","Cell RNA - U-2197 [nTPM]":"0.6","Cell RNA - U-251 MG [nTPM]":"0.7","Cell RNA - U-266\/70 [nTPM]":"2.7","Cell RNA - U-266\/84 [nTPM]":"1.3","Cell RNA - U-698 [nTPM]":"3.9","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.6","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.5","Brain RNA - basal ganglia [nTPM]":"3.6","Brain RNA - cerebellum [nTPM]":"3.8","Brain RNA - cerebral cortex [nTPM]":"4.1","Brain RNA - hippocampal formation [nTPM]":"3.2","Brain RNA - hypothalamus [nTPM]":"3.2","Brain RNA - medulla oblongata [nTPM]":"3.3","Brain RNA - midbrain [nTPM]":"3.2","Brain RNA - pons [nTPM]":"3.6","Brain RNA - spinal cord [nTPM]":"3.0","Brain RNA - thalamus [nTPM]":"3.5","Brain RNA - white matter [nTPM]":"4.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"23.2","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"4.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"83.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"8.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"28.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"53.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"GUCY1A1","Gene synonym":["GC-SA3","GUC1A3","GUCY1A3"],"Ensembl":"ENSG00000164116","Gene description":"Guanylate cyclase 1 soluble subunit alpha 1","Uniprot":["Q02108"],"Chromosome":"4","Position":"155666726-155737059","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["cGMP biosynthesis"],"Molecular function":["Lyase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"38.4","Alveolar cells type 2":"56.1","Breast glandular cells":"37.4","Breast myoepithelial cells":"24.9","Distal tubular cells":"19.6","Ductal cells":"21.8","Smooth muscle cells":"49.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"24.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"8.2","non-classical monocyte":"10.1","plasmacytoid DC":"11.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"35","RNA blood lineage specific nTPM":{"dendritic cells":"11.5","monocytes":"10.1","NK-cells":"8.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HAP1":"6.8","HEK 293":"5.5","Karpas-707":"9.7","MOLT-4":"18.5","RPTEC TERT1":"12.1","RT4":"14.2","SH-SY5Y":"8.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010887","HPA056004","HPA058617"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7100","Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB010887":"AB_259901","HPA056004":"AB_2683007","HPA058617":"AB_2732624"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.77e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.38e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.59e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.59e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-3"},"Tissue RNA - adipose tissue [nTPM]":"14.4","Tissue RNA - adrenal gland [nTPM]":"7.8","Tissue RNA - amygdala [nTPM]":"10.1","Tissue RNA - appendix [nTPM]":"17.0","Tissue RNA - basal ganglia [nTPM]":"24.1","Tissue RNA - bone marrow [nTPM]":"1.2","Tissue RNA - breast [nTPM]":"15.4","Tissue RNA - cerebellum [nTPM]":"2.8","Tissue RNA - cerebral cortex [nTPM]":"14.0","Tissue RNA - cervix [nTPM]":"14.5","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"27.1","Tissue RNA - duodenum [nTPM]":"8.7","Tissue RNA - endometrium 1 [nTPM]":"16.1","Tissue RNA - epididymis [nTPM]":"6.2","Tissue RNA - esophagus [nTPM]":"7.5","Tissue RNA - fallopian tube [nTPM]":"9.5","Tissue RNA - gallbladder [nTPM]":"12.6","Tissue RNA - heart muscle [nTPM]":"33.7","Tissue RNA - hippocampal formation [nTPM]":"12.7","Tissue RNA - hypothalamus [nTPM]":"8.0","Tissue RNA - kidney [nTPM]":"15.6","Tissue RNA - liver [nTPM]":"8.0","Tissue RNA - lung [nTPM]":"21.0","Tissue RNA - lymph node [nTPM]":"8.5","Tissue RNA - medulla oblongata [nTPM]":"5.3","Tissue RNA - midbrain [nTPM]":"10.0","Tissue RNA - ovary [nTPM]":"5.6","Tissue RNA - pancreas [nTPM]":"13.1","Tissue RNA - parathyroid gland [nTPM]":"31.4","Tissue RNA - pituitary gland [nTPM]":"3.9","Tissue RNA - placenta [nTPM]":"25.9","Tissue RNA - pons [nTPM]":"4.5","Tissue RNA - prostate [nTPM]":"25.8","Tissue RNA - rectum [nTPM]":"10.3","Tissue RNA - retina [nTPM]":"17.0","Tissue RNA - salivary gland [nTPM]":"5.3","Tissue RNA - seminal vesicle [nTPM]":"13.9","Tissue RNA - skeletal muscle [nTPM]":"5.1","Tissue RNA - skin 1 [nTPM]":"2.5","Tissue RNA - small intestine [nTPM]":"9.2","Tissue RNA - smooth muscle [nTPM]":"28.9","Tissue RNA - spinal cord [nTPM]":"8.7","Tissue RNA - spleen [nTPM]":"14.1","Tissue RNA - stomach 1 [nTPM]":"8.6","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"10.2","Tissue RNA - thymus [nTPM]":"7.5","Tissue RNA - thyroid gland [nTPM]":"7.2","Tissue RNA - tongue [nTPM]":"18.7","Tissue RNA - tonsil [nTPM]":"9.2","Tissue RNA - urinary bladder [nTPM]":"7.3","Tissue RNA - vagina [nTPM]":"6.6","Tissue RNA - white matter [nTPM]":"8.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"6.8","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"5.5","Cell RNA - HEL [nTPM]":"1.3","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.8","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"3.6","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"9.7","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"18.5","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"4.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"3.0","Cell RNA - RPTEC TERT1 [nTPM]":"12.1","Cell RNA - RT4 [nTPM]":"14.2","Cell RNA - SCLC-21H [nTPM]":"2.5","Cell RNA - SH-SY5Y [nTPM]":"8.7","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.6","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"2.3","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"2.5","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"8.2","Blood RNA - non-classical monocyte [nTPM]":"10.1","Blood RNA - plasmacytoid DC [nTPM]":"11.5","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"10.1","Brain RNA - basal ganglia [nTPM]":"24.1","Brain RNA - cerebellum [nTPM]":"2.8","Brain RNA - cerebral cortex [nTPM]":"14.0","Brain RNA - hippocampal formation [nTPM]":"12.7","Brain RNA - hypothalamus [nTPM]":"8.0","Brain RNA - medulla oblongata [nTPM]":"5.3","Brain RNA - midbrain [nTPM]":"10.0","Brain RNA - pons [nTPM]":"4.5","Brain RNA - spinal cord [nTPM]":"8.7","Brain RNA - thalamus [nTPM]":"10.2","Brain RNA - white matter [nTPM]":"8.5","Single Cell Type RNA - Adipocytes [nTPM]":"38.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"56.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"37.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"6.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"1.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"21.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.7","Single Cell Type RNA - Endothelial cells [nTPM]":"10.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"8.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.2","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"3.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"49.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"GUCY2D","Gene synonym":["CORD6","CYGD","GUC1A4","GUC2D","LCA","LCA1","retGC","RETGC-1","ROS-GC1"],"Ensembl":"ENSG00000132518","Gene description":"Guanylate cyclase 2D, retinal","Uniprot":["Q02846"],"Chromosome":"17","Position":"8002615-8020342","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["cGMP biosynthesis","Sensory transduction","Vision"],"Molecular function":["Lyase"],"Disease involvement":["Cone-rod dystrophy","Congenital stationary night blindness","Disease variant","Leber congenital amaurosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"24","RNA tissue specific nTPM":{"retina":"34.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"62.6","Rod photoreceptor cells":"58.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"31","RNA blood cell specific nTPM":{"plasmacytoid DC":"8.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"50","RNA blood lineage specific nTPM":{"dendritic cells":"8.0"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"JURKAT":"5.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.75e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"34.2","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"1.4","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.3","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"5.9","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"8.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"2.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"62.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - dendritic cells [nTPM]":"2.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"6.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"1.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"14.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.8","Single Cell Type RNA - Muller glia cells [nTPM]":"6.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"58.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.2","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.5"},{"Gene":"GUSB","Gene synonym":[],"Ensembl":"ENSG00000169919","Gene description":"Glucuronidase beta","Uniprot":["P08236"],"Chromosome":"7","Position":"65960684-65982215","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Mucopolysaccharidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"213.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036322","HPA036323"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"330000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA036322":"AB_10670796","HPA036323":"AB_2675059"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Tissue RNA - adipose tissue [nTPM]":"28.4","Tissue RNA - adrenal gland [nTPM]":"18.2","Tissue RNA - amygdala [nTPM]":"11.0","Tissue RNA - appendix [nTPM]":"22.3","Tissue RNA - basal ganglia [nTPM]":"12.3","Tissue RNA - bone marrow [nTPM]":"84.2","Tissue RNA - breast [nTPM]":"80.9","Tissue RNA - cerebellum [nTPM]":"12.0","Tissue RNA - cerebral cortex [nTPM]":"16.1","Tissue RNA - cervix [nTPM]":"26.7","Tissue RNA - choroid plexus [nTPM]":"14.3","Tissue RNA - colon [nTPM]":"38.2","Tissue RNA - duodenum [nTPM]":"36.1","Tissue RNA - endometrium 1 [nTPM]":"26.2","Tissue RNA - epididymis [nTPM]":"41.8","Tissue RNA - esophagus [nTPM]":"16.4","Tissue RNA - fallopian tube [nTPM]":"24.6","Tissue RNA - gallbladder [nTPM]":"27.6","Tissue RNA - heart muscle [nTPM]":"19.6","Tissue RNA - hippocampal formation [nTPM]":"10.7","Tissue RNA - hypothalamus [nTPM]":"11.5","Tissue RNA - kidney [nTPM]":"25.1","Tissue RNA - liver [nTPM]":"104.0","Tissue RNA - lung [nTPM]":"35.7","Tissue RNA - lymph node [nTPM]":"25.6","Tissue RNA - medulla oblongata [nTPM]":"13.2","Tissue RNA - midbrain [nTPM]":"12.2","Tissue RNA - ovary [nTPM]":"19.9","Tissue RNA - pancreas [nTPM]":"33.6","Tissue RNA - parathyroid gland [nTPM]":"30.3","Tissue RNA - pituitary gland [nTPM]":"12.6","Tissue RNA - placenta [nTPM]":"48.2","Tissue RNA - pons [nTPM]":"13.2","Tissue RNA - prostate [nTPM]":"20.2","Tissue RNA - rectum [nTPM]":"41.9","Tissue RNA - retina [nTPM]":"9.7","Tissue RNA - salivary gland [nTPM]":"32.9","Tissue RNA - seminal vesicle [nTPM]":"21.2","Tissue RNA - skeletal muscle [nTPM]":"10.9","Tissue RNA - skin 1 [nTPM]":"18.8","Tissue RNA - small intestine [nTPM]":"29.8","Tissue RNA - smooth muscle [nTPM]":"19.1","Tissue RNA - spinal cord [nTPM]":"11.9","Tissue RNA - spleen [nTPM]":"34.0","Tissue RNA - stomach 1 [nTPM]":"38.1","Tissue RNA - testis [nTPM]":"19.5","Tissue RNA - thalamus [nTPM]":"13.0","Tissue RNA - thymus [nTPM]":"22.7","Tissue RNA - thyroid gland [nTPM]":"27.7","Tissue RNA - tongue [nTPM]":"14.4","Tissue RNA - tonsil [nTPM]":"24.0","Tissue RNA - urinary bladder [nTPM]":"27.3","Tissue RNA - vagina [nTPM]":"15.4","Tissue RNA - white matter [nTPM]":"13.5","Cell RNA - A-431 [nTPM]":"67.0","Cell RNA - A549 [nTPM]":"26.5","Cell RNA - AF22 [nTPM]":"25.2","Cell RNA - AN3-CA [nTPM]":"56.3","Cell RNA - ASC diff [nTPM]":"80.9","Cell RNA - ASC TERT1 [nTPM]":"49.1","Cell RNA - BEWO [nTPM]":"35.3","Cell RNA - BJ [nTPM]":"21.3","Cell RNA - BJ hTERT+ [nTPM]":"56.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"45.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"42.1","Cell RNA - CACO-2 [nTPM]":"37.0","Cell RNA - CAPAN-2 [nTPM]":"67.8","Cell RNA - Daudi [nTPM]":"30.9","Cell RNA - EFO-21 [nTPM]":"32.3","Cell RNA - fHDF\/TERT166 [nTPM]":"26.8","Cell RNA - GAMG [nTPM]":"24.1","Cell RNA - HaCaT [nTPM]":"27.5","Cell RNA - HAP1 [nTPM]":"16.5","Cell RNA - HBEC3-KT [nTPM]":"25.1","Cell RNA - HBF TERT88 [nTPM]":"26.8","Cell RNA - HDLM-2 [nTPM]":"27.3","Cell RNA - HEK 293 [nTPM]":"34.1","Cell RNA - HEL [nTPM]":"41.5","Cell RNA - HeLa [nTPM]":"40.9","Cell RNA - Hep G2 [nTPM]":"27.3","Cell RNA - HHSteC [nTPM]":"39.7","Cell RNA - HL-60 [nTPM]":"89.6","Cell RNA - HMC-1 [nTPM]":"67.1","Cell RNA - HSkMC [nTPM]":"33.4","Cell RNA - hTCEpi [nTPM]":"26.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.3","Cell RNA - hTERT-HME1 [nTPM]":"33.3","Cell RNA - hTERT-RPE1 [nTPM]":"54.5","Cell RNA - HUVEC TERT2 [nTPM]":"39.3","Cell RNA - JURKAT [nTPM]":"18.0","Cell RNA - K-562 [nTPM]":"63.2","Cell RNA - Karpas-707 [nTPM]":"213.5","Cell RNA - LHCN-M2 [nTPM]":"30.5","Cell RNA - MCF7 [nTPM]":"50.3","Cell RNA - MOLT-4 [nTPM]":"34.2","Cell RNA - NB-4 [nTPM]":"92.0","Cell RNA - NTERA-2 [nTPM]":"17.9","Cell RNA - OE19 [nTPM]":"103.0","Cell RNA - PC-3 [nTPM]":"21.0","Cell RNA - REH [nTPM]":"34.4","Cell RNA - RH-30 [nTPM]":"55.9","Cell RNA - RPMI-8226 [nTPM]":"172.4","Cell RNA - RPTEC TERT1 [nTPM]":"29.4","Cell RNA - RT4 [nTPM]":"42.8","Cell RNA - SCLC-21H [nTPM]":"36.2","Cell RNA - SH-SY5Y [nTPM]":"32.7","Cell RNA - SiHa [nTPM]":"55.6","Cell RNA - SK-BR-3 [nTPM]":"129.1","Cell RNA - SK-MEL-30 [nTPM]":"72.3","Cell RNA - SuSa [nTPM]":"29.9","Cell RNA - T-47d [nTPM]":"71.1","Cell RNA - THP-1 [nTPM]":"88.8","Cell RNA - TIME [nTPM]":"28.5","Cell RNA - U-138 MG [nTPM]":"55.3","Cell RNA - U-2 OS [nTPM]":"49.3","Cell RNA - U-2197 [nTPM]":"21.8","Cell RNA - U-251 MG [nTPM]":"53.6","Cell RNA - U-266\/70 [nTPM]":"119.6","Cell RNA - U-266\/84 [nTPM]":"151.9","Cell RNA - U-698 [nTPM]":"50.0","Cell RNA - U-87 MG [nTPM]":"41.0","Cell RNA - U-937 [nTPM]":"116.3","Cell RNA - WM-115 [nTPM]":"68.3","Blood RNA - basophil [nTPM]":"26.0","Blood RNA - classical monocyte [nTPM]":"80.1","Blood RNA - eosinophil [nTPM]":"65.7","Blood RNA - gdT-cell [nTPM]":"32.0","Blood RNA - intermediate monocyte [nTPM]":"103.0","Blood RNA - MAIT T-cell [nTPM]":"28.4","Blood RNA - memory B-cell [nTPM]":"27.7","Blood RNA - memory CD4 T-cell [nTPM]":"24.7","Blood RNA - memory CD8 T-cell [nTPM]":"28.4","Blood RNA - myeloid DC [nTPM]":"80.5","Blood RNA - naive B-cell [nTPM]":"22.6","Blood RNA - naive CD4 T-cell [nTPM]":"16.8","Blood RNA - naive CD8 T-cell [nTPM]":"19.5","Blood RNA - neutrophil [nTPM]":"13.2","Blood RNA - NK-cell [nTPM]":"46.6","Blood RNA - non-classical monocyte [nTPM]":"93.5","Blood RNA - plasmacytoid DC [nTPM]":"34.2","Blood RNA - T-reg [nTPM]":"34.5","Blood RNA - total PBMC [nTPM]":"51.4","Brain RNA - amygdala [nTPM]":"11.0","Brain RNA - basal ganglia [nTPM]":"12.3","Brain RNA - cerebellum [nTPM]":"12.0","Brain RNA - cerebral cortex [nTPM]":"16.1","Brain RNA - hippocampal formation [nTPM]":"10.7","Brain RNA - hypothalamus [nTPM]":"11.5","Brain RNA - medulla oblongata [nTPM]":"13.2","Brain RNA - midbrain [nTPM]":"12.2","Brain RNA - pons [nTPM]":"13.2","Brain RNA - spinal cord [nTPM]":"11.9","Brain RNA - thalamus [nTPM]":"13.0","Brain RNA - white matter [nTPM]":"13.5","Single Cell Type RNA - Adipocytes [nTPM]":"53.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"58.7","Single Cell Type RNA - Astrocytes [nTPM]":"10.1","Single Cell Type RNA - B-cells [nTPM]":"33.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"51.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"29.0","Single Cell Type RNA - Bipolar cells [nTPM]":"12.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"19.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"48.6","Single Cell Type RNA - Club cells [nTPM]":"48.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"81.9","Single Cell Type RNA - dendritic cells [nTPM]":"32.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"52.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"41.1","Single Cell Type RNA - Early spermatids [nTPM]":"59.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"28.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.5","Single Cell Type RNA - Endothelial cells [nTPM]":"39.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"43.0","Single Cell Type RNA - Erythroid cells [nTPM]":"47.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"61.2","Single Cell Type RNA - Fibroblasts [nTPM]":"49.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"49.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"49.4","Single Cell Type RNA - granulocytes [nTPM]":"36.8","Single Cell Type RNA - Granulosa cells [nTPM]":"38.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"37.9","Single Cell Type RNA - Hepatocytes [nTPM]":"72.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"126.4","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"51.6","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"88.1","Single Cell Type RNA - Langerhans cells [nTPM]":"33.2","Single Cell Type RNA - Late spermatids [nTPM]":"46.7","Single Cell Type RNA - Leydig cells [nTPM]":"43.2","Single Cell Type RNA - Macrophages [nTPM]":"78.0","Single Cell Type RNA - Melanocytes [nTPM]":"39.2","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"44.8","Single Cell Type RNA - Muller glia cells [nTPM]":"28.0","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.4","Single Cell Type RNA - Paneth cells [nTPM]":"49.5","Single Cell Type RNA - Peritubular cells [nTPM]":"28.6","Single Cell Type RNA - Plasma cells [nTPM]":"87.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"25.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"50.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"26.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"43.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"20.1","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.0","Single Cell Type RNA - Spermatocytes [nTPM]":"49.6","Single Cell Type RNA - Spermatogonia [nTPM]":"31.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"66.9","Single Cell Type RNA - T-cells [nTPM]":"32.2","Single Cell Type RNA - Theca cells [nTPM]":"24.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"44.3","Single Cell Type RNA - Urothelial cells [nTPM]":"29.6"},{"Gene":"GYG1","Gene synonym":["GYG"],"Ensembl":"ENSG00000163754","Gene description":"Glycogenin 1","Uniprot":["P46976"],"Chromosome":"3","Position":"148991408-149031775","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Glycogen biosynthesis"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Glycogen storage disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"560.0","tongue":"357.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"229.8","Early spermatids":"251.2","Late spermatids":"368.8","Spermatocytes":"296.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030497","HPA073229"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"30000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA030497":"AB_10602326","HPA073229":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.15e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-2"},"Tissue RNA - adipose tissue [nTPM]":"40.3","Tissue RNA - adrenal gland [nTPM]":"31.1","Tissue RNA - amygdala [nTPM]":"30.1","Tissue RNA - appendix [nTPM]":"31.3","Tissue RNA - basal ganglia [nTPM]":"32.2","Tissue RNA - bone marrow [nTPM]":"219.8","Tissue RNA - breast [nTPM]":"33.8","Tissue RNA - cerebellum [nTPM]":"33.1","Tissue RNA - cerebral cortex [nTPM]":"39.4","Tissue RNA - cervix [nTPM]":"36.5","Tissue RNA - choroid plexus [nTPM]":"28.7","Tissue RNA - colon [nTPM]":"152.2","Tissue RNA - duodenum [nTPM]":"16.7","Tissue RNA - endometrium 1 [nTPM]":"64.1","Tissue RNA - epididymis [nTPM]":"38.7","Tissue RNA - esophagus [nTPM]":"53.6","Tissue RNA - fallopian tube [nTPM]":"52.6","Tissue RNA - gallbladder [nTPM]":"23.9","Tissue RNA - heart muscle [nTPM]":"117.8","Tissue RNA - hippocampal formation [nTPM]":"29.9","Tissue RNA - hypothalamus [nTPM]":"44.0","Tissue RNA - kidney [nTPM]":"29.0","Tissue RNA - liver [nTPM]":"18.6","Tissue RNA - lung [nTPM]":"41.1","Tissue RNA - lymph node [nTPM]":"24.8","Tissue RNA - medulla oblongata [nTPM]":"37.0","Tissue RNA - midbrain [nTPM]":"39.7","Tissue RNA - ovary [nTPM]":"43.8","Tissue RNA - pancreas [nTPM]":"42.7","Tissue RNA - parathyroid gland [nTPM]":"25.2","Tissue RNA - pituitary gland [nTPM]":"31.5","Tissue RNA - placenta [nTPM]":"23.0","Tissue RNA - pons [nTPM]":"39.0","Tissue RNA - prostate [nTPM]":"47.3","Tissue RNA - rectum [nTPM]":"25.6","Tissue RNA - retina [nTPM]":"34.3","Tissue RNA - salivary gland [nTPM]":"39.7","Tissue RNA - seminal vesicle [nTPM]":"64.4","Tissue RNA - skeletal muscle [nTPM]":"560.0","Tissue RNA - skin 1 [nTPM]":"21.2","Tissue RNA - small intestine [nTPM]":"37.7","Tissue RNA - smooth muscle [nTPM]":"68.1","Tissue RNA - spinal cord [nTPM]":"35.9","Tissue RNA - spleen [nTPM]":"59.2","Tissue RNA - stomach 1 [nTPM]":"50.7","Tissue RNA - testis [nTPM]":"115.1","Tissue RNA - thalamus [nTPM]":"33.6","Tissue RNA - thymus [nTPM]":"18.0","Tissue RNA - thyroid gland [nTPM]":"21.1","Tissue RNA - tongue [nTPM]":"357.6","Tissue RNA - tonsil [nTPM]":"23.0","Tissue RNA - urinary bladder [nTPM]":"86.1","Tissue RNA - vagina [nTPM]":"30.8","Tissue RNA - white matter [nTPM]":"38.3","Cell RNA - A-431 [nTPM]":"62.7","Cell RNA - A549 [nTPM]":"39.8","Cell RNA - AF22 [nTPM]":"29.0","Cell RNA - AN3-CA [nTPM]":"32.6","Cell RNA - ASC diff [nTPM]":"78.5","Cell RNA - ASC TERT1 [nTPM]":"81.7","Cell RNA - BEWO [nTPM]":"39.5","Cell RNA - BJ [nTPM]":"90.2","Cell RNA - BJ hTERT+ [nTPM]":"74.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"128.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"119.2","Cell RNA - CACO-2 [nTPM]":"52.3","Cell RNA - CAPAN-2 [nTPM]":"62.2","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"43.5","Cell RNA - fHDF\/TERT166 [nTPM]":"105.1","Cell RNA - GAMG [nTPM]":"68.4","Cell RNA - HaCaT [nTPM]":"18.8","Cell RNA - HAP1 [nTPM]":"76.7","Cell RNA - HBEC3-KT [nTPM]":"39.8","Cell RNA - HBF TERT88 [nTPM]":"128.6","Cell RNA - HDLM-2 [nTPM]":"21.1","Cell RNA - HEK 293 [nTPM]":"33.3","Cell RNA - HEL [nTPM]":"47.6","Cell RNA - HeLa [nTPM]":"16.7","Cell RNA - Hep G2 [nTPM]":"59.9","Cell RNA - HHSteC [nTPM]":"70.7","Cell RNA - HL-60 [nTPM]":"49.1","Cell RNA - HMC-1 [nTPM]":"68.8","Cell RNA - HSkMC [nTPM]":"45.1","Cell RNA - hTCEpi [nTPM]":"63.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"42.7","Cell RNA - hTERT-HME1 [nTPM]":"53.3","Cell RNA - hTERT-RPE1 [nTPM]":"66.8","Cell RNA - HUVEC TERT2 [nTPM]":"74.7","Cell RNA - JURKAT [nTPM]":"30.7","Cell RNA - K-562 [nTPM]":"29.8","Cell RNA - Karpas-707 [nTPM]":"109.8","Cell RNA - LHCN-M2 [nTPM]":"74.7","Cell RNA - MCF7 [nTPM]":"110.3","Cell RNA - MOLT-4 [nTPM]":"9.6","Cell RNA - NB-4 [nTPM]":"38.9","Cell RNA - NTERA-2 [nTPM]":"34.9","Cell RNA - OE19 [nTPM]":"48.3","Cell RNA - PC-3 [nTPM]":"32.2","Cell RNA - REH [nTPM]":"26.7","Cell RNA - RH-30 [nTPM]":"43.8","Cell RNA - RPMI-8226 [nTPM]":"89.3","Cell RNA - RPTEC TERT1 [nTPM]":"35.7","Cell RNA - RT4 [nTPM]":"57.6","Cell RNA - SCLC-21H [nTPM]":"23.7","Cell RNA - SH-SY5Y [nTPM]":"11.3","Cell RNA - SiHa [nTPM]":"47.6","Cell RNA - SK-BR-3 [nTPM]":"64.6","Cell RNA - SK-MEL-30 [nTPM]":"54.4","Cell RNA - SuSa [nTPM]":"27.3","Cell RNA - T-47d [nTPM]":"64.4","Cell RNA - THP-1 [nTPM]":"51.4","Cell RNA - TIME [nTPM]":"62.9","Cell RNA - U-138 MG [nTPM]":"65.4","Cell RNA - U-2 OS [nTPM]":"19.4","Cell RNA - U-2197 [nTPM]":"47.4","Cell RNA - U-251 MG [nTPM]":"66.9","Cell RNA - U-266\/70 [nTPM]":"98.7","Cell RNA - U-266\/84 [nTPM]":"59.1","Cell RNA - U-698 [nTPM]":"44.4","Cell RNA - U-87 MG [nTPM]":"55.1","Cell RNA - U-937 [nTPM]":"74.3","Cell RNA - WM-115 [nTPM]":"21.7","Blood RNA - basophil [nTPM]":"22.7","Blood RNA - classical monocyte [nTPM]":"58.1","Blood RNA - eosinophil [nTPM]":"42.4","Blood RNA - gdT-cell [nTPM]":"39.4","Blood RNA - intermediate monocyte [nTPM]":"59.6","Blood RNA - MAIT T-cell [nTPM]":"73.1","Blood RNA - memory B-cell [nTPM]":"15.9","Blood RNA - memory CD4 T-cell [nTPM]":"25.7","Blood RNA - memory CD8 T-cell [nTPM]":"41.3","Blood RNA - myeloid DC [nTPM]":"64.0","Blood RNA - naive B-cell [nTPM]":"14.0","Blood RNA - naive CD4 T-cell [nTPM]":"13.8","Blood RNA - naive CD8 T-cell [nTPM]":"23.5","Blood RNA - neutrophil [nTPM]":"27.0","Blood RNA - NK-cell [nTPM]":"44.3","Blood RNA - non-classical monocyte [nTPM]":"67.9","Blood RNA - plasmacytoid DC [nTPM]":"25.3","Blood RNA - T-reg [nTPM]":"39.4","Blood RNA - total PBMC [nTPM]":"50.1","Brain RNA - amygdala [nTPM]":"30.1","Brain RNA - basal ganglia [nTPM]":"32.2","Brain RNA - cerebellum [nTPM]":"33.1","Brain RNA - cerebral cortex [nTPM]":"39.4","Brain RNA - hippocampal formation [nTPM]":"29.9","Brain RNA - hypothalamus [nTPM]":"44.0","Brain RNA - medulla oblongata [nTPM]":"37.0","Brain RNA - midbrain [nTPM]":"39.7","Brain RNA - pons [nTPM]":"39.0","Brain RNA - spinal cord [nTPM]":"35.9","Brain RNA - thalamus [nTPM]":"33.6","Brain RNA - white matter [nTPM]":"38.3","Single Cell Type RNA - Adipocytes [nTPM]":"27.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.1","Single Cell Type RNA - Astrocytes [nTPM]":"16.3","Single Cell Type RNA - B-cells [nTPM]":"28.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"27.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Bipolar cells [nTPM]":"9.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"229.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"21.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"36.5","Single Cell Type RNA - dendritic cells [nTPM]":"50.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"27.4","Single Cell Type RNA - Ductal cells [nTPM]":"43.4","Single Cell Type RNA - Early spermatids [nTPM]":"251.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.2","Single Cell Type RNA - Endothelial cells [nTPM]":"32.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.4","Single Cell Type RNA - Erythroid cells [nTPM]":"12.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"77.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"47.2","Single Cell Type RNA - Fibroblasts [nTPM]":"45.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.5","Single Cell Type RNA - granulocytes [nTPM]":"18.3","Single Cell Type RNA - Granulosa cells [nTPM]":"19.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"45.3","Single Cell Type RNA - Hepatocytes [nTPM]":"13.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"95.3","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.0","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"87.1","Single Cell Type RNA - Langerhans cells [nTPM]":"26.3","Single Cell Type RNA - Late spermatids [nTPM]":"368.8","Single Cell Type RNA - Leydig cells [nTPM]":"53.1","Single Cell Type RNA - Macrophages [nTPM]":"56.2","Single Cell Type RNA - Melanocytes [nTPM]":"40.9","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"56.2","Single Cell Type RNA - Muller glia cells [nTPM]":"132.1","Single Cell Type RNA - NK-cells [nTPM]":"36.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"31.6","Single Cell Type RNA - Paneth cells [nTPM]":"14.3","Single Cell Type RNA - Peritubular cells [nTPM]":"76.8","Single Cell Type RNA - Plasma cells [nTPM]":"104.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"45.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.0","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"35.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"50.3","Single Cell Type RNA - Spermatocytes [nTPM]":"296.7","Single Cell Type RNA - Spermatogonia [nTPM]":"52.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"29.3","Single Cell Type RNA - T-cells [nTPM]":"61.2","Single Cell Type RNA - Theca cells [nTPM]":"33.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.2","Single Cell Type RNA - Urothelial cells [nTPM]":"19.6"},{"Gene":"GYS1","Gene synonym":["GSY","GYS"],"Ensembl":"ENSG00000104812","Gene description":"Glycogen synthase 1","Uniprot":["P13807"],"Chromosome":"19","Position":"48968130-48993310","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Glycogen biosynthesis"],"Molecular function":["Allosteric enzyme","Glycosyltransferase","Transferase"],"Disease involvement":["Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"heart muscle":"118.5","skeletal muscle":"319.4","tongue":"201.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"67.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB007793","HPA041598"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Microtubules","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB007793":"AB_562291","HPA041598":"AB_2677571"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.46e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Tissue RNA - adipose tissue [nTPM]":"32.4","Tissue RNA - adrenal gland [nTPM]":"26.3","Tissue RNA - amygdala [nTPM]":"17.9","Tissue RNA - appendix [nTPM]":"16.2","Tissue RNA - basal ganglia [nTPM]":"18.8","Tissue RNA - bone marrow [nTPM]":"46.0","Tissue RNA - breast [nTPM]":"23.7","Tissue RNA - cerebellum [nTPM]":"26.4","Tissue RNA - cerebral cortex [nTPM]":"23.3","Tissue RNA - cervix [nTPM]":"17.1","Tissue RNA - choroid plexus [nTPM]":"22.2","Tissue RNA - colon [nTPM]":"21.7","Tissue RNA - duodenum [nTPM]":"15.3","Tissue RNA - endometrium 1 [nTPM]":"18.8","Tissue RNA - epididymis [nTPM]":"8.9","Tissue RNA - esophagus [nTPM]":"38.2","Tissue RNA - fallopian tube [nTPM]":"18.7","Tissue RNA - gallbladder [nTPM]":"10.1","Tissue RNA - heart muscle [nTPM]":"118.5","Tissue RNA - hippocampal formation [nTPM]":"19.7","Tissue RNA - hypothalamus [nTPM]":"17.6","Tissue RNA - kidney [nTPM]":"21.8","Tissue RNA - liver [nTPM]":"14.9","Tissue RNA - lung [nTPM]":"16.0","Tissue RNA - lymph node [nTPM]":"15.5","Tissue RNA - medulla oblongata [nTPM]":"22.2","Tissue RNA - midbrain [nTPM]":"20.9","Tissue RNA - ovary [nTPM]":"19.7","Tissue RNA - pancreas [nTPM]":"13.6","Tissue RNA - parathyroid gland [nTPM]":"15.7","Tissue RNA - pituitary gland [nTPM]":"15.5","Tissue RNA - placenta [nTPM]":"11.3","Tissue RNA - pons [nTPM]":"19.6","Tissue RNA - prostate [nTPM]":"27.4","Tissue RNA - rectum [nTPM]":"14.7","Tissue RNA - retina [nTPM]":"19.2","Tissue RNA - salivary gland [nTPM]":"22.2","Tissue RNA - seminal vesicle [nTPM]":"15.5","Tissue RNA - skeletal muscle [nTPM]":"319.4","Tissue RNA - skin 1 [nTPM]":"20.7","Tissue RNA - small intestine [nTPM]":"19.9","Tissue RNA - smooth muscle [nTPM]":"16.7","Tissue RNA - spinal cord [nTPM]":"16.4","Tissue RNA - spleen [nTPM]":"18.5","Tissue RNA - stomach 1 [nTPM]":"23.2","Tissue RNA - testis [nTPM]":"6.1","Tissue RNA - thalamus [nTPM]":"20.2","Tissue RNA - thymus [nTPM]":"14.7","Tissue RNA - thyroid gland [nTPM]":"15.9","Tissue RNA - tongue [nTPM]":"201.6","Tissue RNA - tonsil [nTPM]":"14.4","Tissue RNA - urinary bladder [nTPM]":"24.3","Tissue RNA - vagina [nTPM]":"23.2","Tissue RNA - white matter [nTPM]":"18.3","Cell RNA - A-431 [nTPM]":"67.3","Cell RNA - A549 [nTPM]":"26.3","Cell RNA - AF22 [nTPM]":"19.0","Cell RNA - AN3-CA [nTPM]":"26.3","Cell RNA - ASC diff [nTPM]":"43.2","Cell RNA - ASC TERT1 [nTPM]":"16.9","Cell RNA - BEWO [nTPM]":"37.6","Cell RNA - BJ [nTPM]":"45.5","Cell RNA - BJ hTERT+ [nTPM]":"31.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"46.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"54.3","Cell RNA - CACO-2 [nTPM]":"25.8","Cell RNA - CAPAN-2 [nTPM]":"21.3","Cell RNA - Daudi [nTPM]":"28.0","Cell RNA - EFO-21 [nTPM]":"27.0","Cell RNA - fHDF\/TERT166 [nTPM]":"44.7","Cell RNA - GAMG [nTPM]":"12.4","Cell RNA - HaCaT [nTPM]":"46.6","Cell RNA - HAP1 [nTPM]":"32.0","Cell RNA - HBEC3-KT [nTPM]":"57.7","Cell RNA - HBF TERT88 [nTPM]":"40.6","Cell RNA - HDLM-2 [nTPM]":"17.4","Cell RNA - HEK 293 [nTPM]":"46.5","Cell RNA - HEL [nTPM]":"23.1","Cell RNA - HeLa [nTPM]":"33.3","Cell RNA - Hep G2 [nTPM]":"23.1","Cell RNA - HHSteC [nTPM]":"24.3","Cell RNA - HL-60 [nTPM]":"25.4","Cell RNA - HMC-1 [nTPM]":"15.9","Cell RNA - HSkMC [nTPM]":"41.8","Cell RNA - hTCEpi [nTPM]":"27.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"30.2","Cell RNA - hTERT-HME1 [nTPM]":"25.4","Cell RNA - hTERT-RPE1 [nTPM]":"40.5","Cell RNA - HUVEC TERT2 [nTPM]":"39.8","Cell RNA - JURKAT [nTPM]":"28.8","Cell RNA - K-562 [nTPM]":"16.4","Cell RNA - Karpas-707 [nTPM]":"36.1","Cell RNA - LHCN-M2 [nTPM]":"59.4","Cell RNA - MCF7 [nTPM]":"25.4","Cell RNA - MOLT-4 [nTPM]":"31.8","Cell RNA - NB-4 [nTPM]":"21.9","Cell RNA - NTERA-2 [nTPM]":"10.2","Cell RNA - OE19 [nTPM]":"29.0","Cell RNA - PC-3 [nTPM]":"29.8","Cell RNA - REH [nTPM]":"26.6","Cell RNA - RH-30 [nTPM]":"33.2","Cell RNA - RPMI-8226 [nTPM]":"27.5","Cell RNA - RPTEC TERT1 [nTPM]":"46.7","Cell RNA - RT4 [nTPM]":"70.6","Cell RNA - SCLC-21H [nTPM]":"11.8","Cell RNA - SH-SY5Y [nTPM]":"16.4","Cell RNA - SiHa [nTPM]":"40.5","Cell RNA - SK-BR-3 [nTPM]":"52.1","Cell RNA - SK-MEL-30 [nTPM]":"10.4","Cell RNA - SuSa [nTPM]":"25.2","Cell RNA - T-47d [nTPM]":"27.7","Cell RNA - THP-1 [nTPM]":"26.1","Cell RNA - TIME [nTPM]":"31.0","Cell RNA - U-138 MG [nTPM]":"57.1","Cell RNA - U-2 OS [nTPM]":"22.0","Cell RNA - U-2197 [nTPM]":"26.1","Cell RNA - U-251 MG [nTPM]":"50.5","Cell RNA - U-266\/70 [nTPM]":"29.8","Cell RNA - U-266\/84 [nTPM]":"33.1","Cell RNA - U-698 [nTPM]":"13.5","Cell RNA - U-87 MG [nTPM]":"58.3","Cell RNA - U-937 [nTPM]":"22.2","Cell RNA - WM-115 [nTPM]":"13.1","Blood RNA - basophil [nTPM]":"7.7","Blood RNA - classical monocyte [nTPM]":"9.4","Blood RNA - eosinophil [nTPM]":"6.6","Blood RNA - gdT-cell [nTPM]":"7.0","Blood RNA - intermediate monocyte [nTPM]":"5.3","Blood RNA - MAIT T-cell [nTPM]":"8.6","Blood RNA - memory B-cell [nTPM]":"5.2","Blood RNA - memory CD4 T-cell [nTPM]":"6.0","Blood RNA - memory CD8 T-cell [nTPM]":"6.5","Blood RNA - myeloid DC [nTPM]":"13.4","Blood RNA - naive B-cell [nTPM]":"3.9","Blood RNA - naive CD4 T-cell [nTPM]":"4.7","Blood RNA - naive CD8 T-cell [nTPM]":"4.4","Blood RNA - neutrophil [nTPM]":"3.7","Blood RNA - NK-cell [nTPM]":"10.6","Blood RNA - non-classical monocyte [nTPM]":"8.0","Blood RNA - plasmacytoid DC [nTPM]":"7.2","Blood RNA - T-reg [nTPM]":"8.6","Blood RNA - total PBMC [nTPM]":"7.1","Brain RNA - amygdala [nTPM]":"17.9","Brain RNA - basal ganglia [nTPM]":"18.8","Brain RNA - cerebellum [nTPM]":"26.4","Brain RNA - cerebral cortex [nTPM]":"23.3","Brain RNA - hippocampal formation [nTPM]":"19.7","Brain RNA - hypothalamus [nTPM]":"17.6","Brain RNA - medulla oblongata [nTPM]":"22.2","Brain RNA - midbrain [nTPM]":"20.9","Brain RNA - pons [nTPM]":"19.6","Brain RNA - spinal cord [nTPM]":"16.4","Brain RNA - thalamus [nTPM]":"20.2","Brain RNA - white matter [nTPM]":"18.3","Single Cell Type RNA - Adipocytes [nTPM]":"3.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.2","Single Cell Type RNA - Astrocytes [nTPM]":"21.9","Single Cell Type RNA - B-cells [nTPM]":"5.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"4.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"67.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"5.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.6","Single Cell Type RNA - dendritic cells [nTPM]":"6.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"8.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.9","Single Cell Type RNA - Endothelial cells [nTPM]":"7.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"4.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"31.7","Single Cell Type RNA - Fibroblasts [nTPM]":"5.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.9","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"6.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.7","Single Cell Type RNA - Hepatocytes [nTPM]":"5.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"16.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.2","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"7.0","Single Cell Type RNA - Langerhans cells [nTPM]":"5.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"5.3","Single Cell Type RNA - Macrophages [nTPM]":"7.2","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"9.8","Single Cell Type RNA - Muller glia cells [nTPM]":"3.3","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.8","Single Cell Type RNA - Paneth cells [nTPM]":"8.2","Single Cell Type RNA - Peritubular cells [nTPM]":"5.7","Single Cell Type RNA - Plasma cells [nTPM]":"9.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.3","Single Cell Type RNA - Spermatogonia [nTPM]":"2.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.0","Single Cell Type RNA - T-cells [nTPM]":"5.2","Single Cell Type RNA - Theca cells [nTPM]":"3.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.7","Single Cell Type RNA - Urothelial cells [nTPM]":"3.3"},{"Gene":"GYS2","Gene synonym":[],"Ensembl":"ENSG00000111713","Gene description":"Glycogen synthase 2","Uniprot":["P54840"],"Chromosome":"12","Position":"21536107-21604847","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Glycogen biosynthesis"],"Molecular function":["Allosteric enzyme","Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant","Glycogen storage disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"30","RNA tissue specific nTPM":{"liver":"173.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Hepatocytes":"63.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"29","RNA cancer specific FPKM":{"liver cancer":"12.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039482"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039482":"AB_10795107"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.62e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-4"},"Tissue RNA - adipose tissue [nTPM]":"3.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.0","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"2.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"5.7","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"173.8","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.5","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"1.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"5.0","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"63.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"H6PD","Gene synonym":["GDH","H6PDH"],"Ensembl":"ENSG00000049239","Gene description":"Hexose-6-phosphate dehydrogenase\/glucose 1-dehydrogenase","Uniprot":["O95479"],"Chromosome":"1","Position":"9234774-9271337","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism","Glucose metabolism"],"Molecular function":["Hydrolase","Multifunctional enzyme","Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"94.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"164.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"68.9","ASC TERT1":"78.9","HSkMC":"77.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004824","HPA005440"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"140000000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA004824":"AB_1079037","HPA005440":"AB_1079036"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Tissue RNA - adipose tissue [nTPM]":"29.0","Tissue RNA - adrenal gland [nTPM]":"30.5","Tissue RNA - amygdala [nTPM]":"7.5","Tissue RNA - appendix [nTPM]":"12.6","Tissue RNA - basal ganglia [nTPM]":"11.6","Tissue RNA - bone marrow [nTPM]":"9.7","Tissue RNA - breast [nTPM]":"23.0","Tissue RNA - cerebellum [nTPM]":"8.2","Tissue RNA - cerebral cortex [nTPM]":"9.0","Tissue RNA - cervix [nTPM]":"22.6","Tissue RNA - choroid plexus [nTPM]":"18.8","Tissue RNA - colon [nTPM]":"15.1","Tissue RNA - duodenum [nTPM]":"11.2","Tissue RNA - endometrium 1 [nTPM]":"25.7","Tissue RNA - epididymis [nTPM]":"14.4","Tissue RNA - esophagus [nTPM]":"13.5","Tissue RNA - fallopian tube [nTPM]":"28.3","Tissue RNA - gallbladder [nTPM]":"12.6","Tissue RNA - heart muscle [nTPM]":"18.9","Tissue RNA - hippocampal formation [nTPM]":"6.4","Tissue RNA - hypothalamus [nTPM]":"7.8","Tissue RNA - kidney [nTPM]":"11.5","Tissue RNA - liver [nTPM]":"94.5","Tissue RNA - lung [nTPM]":"20.3","Tissue RNA - lymph node [nTPM]":"12.4","Tissue RNA - medulla oblongata [nTPM]":"14.4","Tissue RNA - midbrain [nTPM]":"10.8","Tissue RNA - ovary [nTPM]":"44.9","Tissue RNA - pancreas [nTPM]":"18.9","Tissue RNA - parathyroid gland [nTPM]":"10.6","Tissue RNA - pituitary gland [nTPM]":"12.7","Tissue RNA - placenta [nTPM]":"14.1","Tissue RNA - pons [nTPM]":"11.4","Tissue RNA - prostate [nTPM]":"19.5","Tissue RNA - rectum [nTPM]":"9.1","Tissue RNA - retina [nTPM]":"4.2","Tissue RNA - salivary gland [nTPM]":"56.2","Tissue RNA - seminal vesicle [nTPM]":"13.1","Tissue RNA - skeletal muscle [nTPM]":"48.3","Tissue RNA - skin 1 [nTPM]":"35.7","Tissue RNA - small intestine [nTPM]":"16.8","Tissue RNA - smooth muscle [nTPM]":"16.6","Tissue RNA - spinal cord [nTPM]":"9.6","Tissue RNA - spleen [nTPM]":"14.5","Tissue RNA - stomach 1 [nTPM]":"18.7","Tissue RNA - testis [nTPM]":"8.1","Tissue RNA - thalamus [nTPM]":"11.4","Tissue RNA - thymus [nTPM]":"13.1","Tissue RNA - thyroid gland [nTPM]":"14.7","Tissue RNA - tongue [nTPM]":"21.0","Tissue RNA - tonsil [nTPM]":"11.4","Tissue RNA - urinary bladder [nTPM]":"16.7","Tissue RNA - vagina [nTPM]":"16.5","Tissue RNA - white matter [nTPM]":"10.9","Cell RNA - A-431 [nTPM]":"9.9","Cell RNA - A549 [nTPM]":"8.0","Cell RNA - AF22 [nTPM]":"6.8","Cell RNA - AN3-CA [nTPM]":"25.5","Cell RNA - ASC diff [nTPM]":"68.9","Cell RNA - ASC TERT1 [nTPM]":"78.9","Cell RNA - BEWO [nTPM]":"6.4","Cell RNA - BJ [nTPM]":"9.8","Cell RNA - BJ hTERT+ [nTPM]":"24.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.9","Cell RNA - CACO-2 [nTPM]":"1.5","Cell RNA - CAPAN-2 [nTPM]":"20.1","Cell RNA - Daudi [nTPM]":"10.9","Cell RNA - EFO-21 [nTPM]":"11.2","Cell RNA - fHDF\/TERT166 [nTPM]":"15.3","Cell RNA - GAMG [nTPM]":"9.1","Cell RNA - HaCaT [nTPM]":"10.3","Cell RNA - HAP1 [nTPM]":"1.8","Cell RNA - HBEC3-KT [nTPM]":"4.8","Cell RNA - HBF TERT88 [nTPM]":"10.3","Cell RNA - HDLM-2 [nTPM]":"32.8","Cell RNA - HEK 293 [nTPM]":"2.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"2.8","Cell RNA - Hep G2 [nTPM]":"6.7","Cell RNA - HHSteC [nTPM]":"38.6","Cell RNA - HL-60 [nTPM]":"3.5","Cell RNA - HMC-1 [nTPM]":"4.1","Cell RNA - HSkMC [nTPM]":"77.7","Cell RNA - hTCEpi [nTPM]":"9.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"17.2","Cell RNA - hTERT-HME1 [nTPM]":"11.1","Cell RNA - hTERT-RPE1 [nTPM]":"15.6","Cell RNA - HUVEC TERT2 [nTPM]":"32.9","Cell RNA - JURKAT [nTPM]":"5.9","Cell RNA - K-562 [nTPM]":"2.9","Cell RNA - Karpas-707 [nTPM]":"18.2","Cell RNA - LHCN-M2 [nTPM]":"14.0","Cell RNA - MCF7 [nTPM]":"5.7","Cell RNA - MOLT-4 [nTPM]":"3.9","Cell RNA - NB-4 [nTPM]":"8.2","Cell RNA - NTERA-2 [nTPM]":"3.7","Cell RNA - OE19 [nTPM]":"7.5","Cell RNA - PC-3 [nTPM]":"4.6","Cell RNA - REH [nTPM]":"1.2","Cell RNA - RH-30 [nTPM]":"0.9","Cell RNA - RPMI-8226 [nTPM]":"9.3","Cell RNA - RPTEC TERT1 [nTPM]":"9.1","Cell RNA - RT4 [nTPM]":"4.0","Cell RNA - SCLC-21H [nTPM]":"2.3","Cell RNA - SH-SY5Y [nTPM]":"12.0","Cell RNA - SiHa [nTPM]":"12.9","Cell RNA - SK-BR-3 [nTPM]":"10.0","Cell RNA - SK-MEL-30 [nTPM]":"12.0","Cell RNA - SuSa [nTPM]":"4.7","Cell RNA - T-47d [nTPM]":"7.5","Cell RNA - THP-1 [nTPM]":"17.4","Cell RNA - TIME [nTPM]":"32.9","Cell RNA - U-138 MG [nTPM]":"24.3","Cell RNA - U-2 OS [nTPM]":"3.9","Cell RNA - U-2197 [nTPM]":"6.2","Cell RNA - U-251 MG [nTPM]":"2.8","Cell RNA - U-266\/70 [nTPM]":"24.1","Cell RNA - U-266\/84 [nTPM]":"7.6","Cell RNA - U-698 [nTPM]":"2.5","Cell RNA - U-87 MG [nTPM]":"40.8","Cell RNA - U-937 [nTPM]":"15.6","Cell RNA - WM-115 [nTPM]":"15.7","Blood RNA - basophil [nTPM]":"1.6","Blood RNA - classical monocyte [nTPM]":"2.3","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"2.4","Blood RNA - MAIT T-cell [nTPM]":"1.3","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"1.2","Blood RNA - memory CD8 T-cell [nTPM]":"1.5","Blood RNA - myeloid DC [nTPM]":"1.0","Blood RNA - naive B-cell [nTPM]":"1.6","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"1.1","Blood RNA - neutrophil [nTPM]":"1.5","Blood RNA - NK-cell [nTPM]":"1.2","Blood RNA - non-classical monocyte [nTPM]":"2.3","Blood RNA - plasmacytoid DC [nTPM]":"1.4","Blood RNA - T-reg [nTPM]":"1.1","Blood RNA - total PBMC [nTPM]":"1.5","Brain RNA - amygdala [nTPM]":"7.5","Brain RNA - basal ganglia [nTPM]":"11.6","Brain RNA - cerebellum [nTPM]":"8.2","Brain RNA - cerebral cortex [nTPM]":"9.0","Brain RNA - hippocampal formation [nTPM]":"6.4","Brain RNA - hypothalamus [nTPM]":"7.8","Brain RNA - medulla oblongata [nTPM]":"14.4","Brain RNA - midbrain [nTPM]":"10.8","Brain RNA - pons [nTPM]":"11.4","Brain RNA - spinal cord [nTPM]":"9.6","Brain RNA - thalamus [nTPM]":"11.4","Brain RNA - white matter [nTPM]":"10.9","Single Cell Type RNA - Adipocytes [nTPM]":"24.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.5","Single Cell Type RNA - Astrocytes [nTPM]":"17.9","Single Cell Type RNA - B-cells [nTPM]":"10.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Bipolar cells [nTPM]":"19.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"58.6","Single Cell Type RNA - Club cells [nTPM]":"18.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.2","Single Cell Type RNA - dendritic cells [nTPM]":"9.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"22.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"36.0","Single Cell Type RNA - Endothelial cells [nTPM]":"19.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.8","Single Cell Type RNA - Erythroid cells [nTPM]":"9.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.5","Single Cell Type RNA - Fibroblasts [nTPM]":"33.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.5","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"29.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.6","Single Cell Type RNA - Hepatocytes [nTPM]":"164.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.1","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.1","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"25.4","Single Cell Type RNA - Langerhans cells [nTPM]":"11.4","Single Cell Type RNA - Late spermatids [nTPM]":"2.9","Single Cell Type RNA - Leydig cells [nTPM]":"48.1","Single Cell Type RNA - Macrophages [nTPM]":"14.2","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"51.6","Single Cell Type RNA - Muller glia cells [nTPM]":"10.4","Single Cell Type RNA - NK-cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.0","Single Cell Type RNA - Paneth cells [nTPM]":"17.0","Single Cell Type RNA - Peritubular cells [nTPM]":"36.9","Single Cell Type RNA - Plasma cells [nTPM]":"4.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"50.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.7","Single Cell Type RNA - Spermatocytes [nTPM]":"4.6","Single Cell Type RNA - Spermatogonia [nTPM]":"5.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.9","Single Cell Type RNA - T-cells [nTPM]":"11.6","Single Cell Type RNA - Theca cells [nTPM]":"26.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.6","Single Cell Type RNA - Urothelial cells [nTPM]":"14.2"},{"Gene":"HAAO","Gene synonym":[],"Ensembl":"ENSG00000162882","Gene description":"3-hydroxyanthranilate 3,4-dioxygenase","Uniprot":["P46952"],"Chromosome":"2","Position":"42767089-42792593","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Pyridine nucleotide biosynthesis"],"Molecular function":["Dioxygenase","Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"liver":"295.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Hepatocytes":"209.8","Proximal enterocytes":"236.8","Proximal tubular cells":"162.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"liver cancer":"46.5","renal cancer":"13.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"23.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"23.2","granulocytes":"19.2","monocytes":"17.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"14.0","Hep G2":"49.4","REH":"9.9","THP-1":"9.2"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036394","HPA042024"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"580000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036394":"AB_10673131","HPA042024":"AB_2677803"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.77e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Tissue RNA - adipose tissue [nTPM]":"8.7","Tissue RNA - adrenal gland [nTPM]":"5.4","Tissue RNA - amygdala [nTPM]":"1.8","Tissue RNA - appendix [nTPM]":"5.9","Tissue RNA - basal ganglia [nTPM]":"2.1","Tissue RNA - bone marrow [nTPM]":"4.1","Tissue RNA - breast [nTPM]":"12.9","Tissue RNA - cerebellum [nTPM]":"2.1","Tissue RNA - cerebral cortex [nTPM]":"2.5","Tissue RNA - cervix [nTPM]":"16.0","Tissue RNA - choroid plexus [nTPM]":"3.3","Tissue RNA - colon [nTPM]":"13.2","Tissue RNA - duodenum [nTPM]":"23.1","Tissue RNA - endometrium 1 [nTPM]":"10.5","Tissue RNA - epididymis [nTPM]":"14.5","Tissue RNA - esophagus [nTPM]":"6.0","Tissue RNA - fallopian tube [nTPM]":"10.6","Tissue RNA - gallbladder [nTPM]":"6.1","Tissue RNA - heart muscle [nTPM]":"7.0","Tissue RNA - hippocampal formation [nTPM]":"1.8","Tissue RNA - hypothalamus [nTPM]":"2.3","Tissue RNA - kidney [nTPM]":"41.8","Tissue RNA - liver [nTPM]":"295.8","Tissue RNA - lung [nTPM]":"5.7","Tissue RNA - lymph node [nTPM]":"6.1","Tissue RNA - medulla oblongata [nTPM]":"2.0","Tissue RNA - midbrain [nTPM]":"2.5","Tissue RNA - ovary [nTPM]":"14.0","Tissue RNA - pancreas [nTPM]":"26.3","Tissue RNA - parathyroid gland [nTPM]":"2.9","Tissue RNA - pituitary gland [nTPM]":"4.5","Tissue RNA - placenta [nTPM]":"8.5","Tissue RNA - pons [nTPM]":"2.3","Tissue RNA - prostate [nTPM]":"10.1","Tissue RNA - rectum [nTPM]":"11.6","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"3.8","Tissue RNA - seminal vesicle [nTPM]":"11.3","Tissue RNA - skeletal muscle [nTPM]":"2.4","Tissue RNA - skin 1 [nTPM]":"5.0","Tissue RNA - small intestine [nTPM]":"40.8","Tissue RNA - smooth muscle [nTPM]":"4.7","Tissue RNA - spinal cord [nTPM]":"2.1","Tissue RNA - spleen [nTPM]":"5.4","Tissue RNA - stomach 1 [nTPM]":"9.6","Tissue RNA - testis [nTPM]":"1.8","Tissue RNA - thalamus [nTPM]":"2.1","Tissue RNA - thymus [nTPM]":"4.0","Tissue RNA - thyroid gland [nTPM]":"5.8","Tissue RNA - tongue [nTPM]":"3.2","Tissue RNA - tonsil [nTPM]":"4.5","Tissue RNA - urinary bladder [nTPM]":"15.8","Tissue RNA - vagina [nTPM]":"9.0","Tissue RNA - white matter [nTPM]":"2.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.6","Cell RNA - CACO-2 [nTPM]":"14.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.6","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"4.7","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.8","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.4","Cell RNA - HEL [nTPM]":"5.6","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"49.4","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"1.9","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"2.3","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.5","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"2.6","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"9.9","Cell RNA - RH-30 [nTPM]":"1.1","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.6","Cell RNA - SK-BR-3 [nTPM]":"1.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.3","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"9.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"1.7","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"7.9","Blood RNA - classical monocyte [nTPM]":"17.4","Blood RNA - eosinophil [nTPM]":"19.2","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"10.5","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"3.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"23.2","Blood RNA - naive B-cell [nTPM]":"3.9","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"5.5","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"2.9","Blood RNA - plasmacytoid DC [nTPM]":"7.7","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"5.6","Brain RNA - amygdala [nTPM]":"1.8","Brain RNA - basal ganglia [nTPM]":"2.1","Brain RNA - cerebellum [nTPM]":"2.1","Brain RNA - cerebral cortex [nTPM]":"2.5","Brain RNA - hippocampal formation [nTPM]":"1.8","Brain RNA - hypothalamus [nTPM]":"2.3","Brain RNA - medulla oblongata [nTPM]":"2.0","Brain RNA - midbrain [nTPM]":"2.5","Brain RNA - pons [nTPM]":"2.3","Brain RNA - spinal cord [nTPM]":"2.1","Brain RNA - thalamus [nTPM]":"2.1","Brain RNA - white matter [nTPM]":"2.3","Single Cell Type RNA - Adipocytes [nTPM]":"2.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"3.6","Single Cell Type RNA - B-cells [nTPM]":"3.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"1.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - dendritic cells [nTPM]":"2.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"7.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"12.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"18.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"30.4","Single Cell Type RNA - Granulosa cells [nTPM]":"1.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.6","Single Cell Type RNA - Hepatocytes [nTPM]":"209.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"21.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"13.5","Single Cell Type RNA - Langerhans cells [nTPM]":"4.9","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"12.5","Single Cell Type RNA - Macrophages [nTPM]":"8.7","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"8.4","Single Cell Type RNA - Muller glia cells [nTPM]":"3.6","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.8","Single Cell Type RNA - Paneth cells [nTPM]":"28.7","Single Cell Type RNA - Peritubular cells [nTPM]":"10.5","Single Cell Type RNA - Plasma cells [nTPM]":"0.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"236.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"162.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"37.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - T-cells [nTPM]":"1.2","Single Cell Type RNA - Theca cells [nTPM]":"2.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"25.5","Single Cell Type RNA - Urothelial cells [nTPM]":"2.7"},{"Gene":"HABP2","Gene synonym":["FSAP","HABP","HGFAL","PHBP"],"Ensembl":"ENSG00000148702","Gene description":"Hyaluronan binding protein 2","Uniprot":["Q14520"],"Chromosome":"10","Position":"113550837-113589602","Protein class":["Candidate cardiovascular disease genes","Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"liver":"437.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cholangiocytes":"124.4","Hepatocytes":"221.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"liver cancer":"92.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"OE19":"64.7","RPTEC TERT1":"50.9"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019518"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":20200000000,"Blood concentration - Conc. blood MS [pg\/L]":"4400000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA019518":"AB_1850467"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.05e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.9","Tissue RNA - cervix [nTPM]":"0.9","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"3.1","Tissue RNA - endometrium 1 [nTPM]":"2.9","Tissue RNA - epididymis [nTPM]":"1.7","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"2.2","Tissue RNA - gallbladder [nTPM]":"36.0","Tissue RNA - heart muscle [nTPM]":"3.8","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"14.2","Tissue RNA - liver [nTPM]":"437.3","Tissue RNA - lung [nTPM]":"0.8","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"17.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.8","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"12.1","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"2.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"9.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"2.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.8","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"64.7","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"50.9","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.9","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"2.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"124.4","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"31.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.8","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"221.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"5.7","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"HACD1","Gene synonym":["CAP","PTPLA"],"Ensembl":"ENSG00000165996","Gene description":"3-hydroxyacyl-CoA dehydratase 1","Uniprot":["B0YJ81"],"Chromosome":"10","Position":"17589032-17617374","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Developmental protein","Lyase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"73.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cardiomyocytes":"143.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"11","RNA blood cell specific nTPM":{"T-reg":"55.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"T-cells":"55.7"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.7","Tissue RNA - adrenal gland [nTPM]":"7.0","Tissue RNA - amygdala [nTPM]":"3.1","Tissue RNA - appendix [nTPM]":"5.0","Tissue RNA - basal ganglia [nTPM]":"3.5","Tissue RNA - bone marrow [nTPM]":"8.0","Tissue RNA - breast [nTPM]":"8.8","Tissue RNA - cerebellum [nTPM]":"10.7","Tissue RNA - cerebral cortex [nTPM]":"4.6","Tissue RNA - cervix [nTPM]":"6.8","Tissue RNA - choroid plexus [nTPM]":"2.9","Tissue RNA - colon [nTPM]":"31.9","Tissue RNA - duodenum [nTPM]":"2.8","Tissue RNA - endometrium 1 [nTPM]":"22.1","Tissue RNA - epididymis [nTPM]":"3.3","Tissue RNA - esophagus [nTPM]":"7.8","Tissue RNA - fallopian tube [nTPM]":"10.3","Tissue RNA - gallbladder [nTPM]":"3.6","Tissue RNA - heart muscle [nTPM]":"73.0","Tissue RNA - hippocampal formation [nTPM]":"3.0","Tissue RNA - hypothalamus [nTPM]":"6.5","Tissue RNA - kidney [nTPM]":"5.0","Tissue RNA - liver [nTPM]":"1.6","Tissue RNA - lung [nTPM]":"9.7","Tissue RNA - lymph node [nTPM]":"1.3","Tissue RNA - medulla oblongata [nTPM]":"5.5","Tissue RNA - midbrain [nTPM]":"5.2","Tissue RNA - ovary [nTPM]":"4.3","Tissue RNA - pancreas [nTPM]":"2.7","Tissue RNA - parathyroid gland [nTPM]":"0.5","Tissue RNA - pituitary gland [nTPM]":"3.7","Tissue RNA - placenta [nTPM]":"1.6","Tissue RNA - pons [nTPM]":"5.0","Tissue RNA - prostate [nTPM]":"11.9","Tissue RNA - rectum [nTPM]":"3.8","Tissue RNA - retina [nTPM]":"2.3","Tissue RNA - salivary gland [nTPM]":"2.7","Tissue RNA - seminal vesicle [nTPM]":"16.7","Tissue RNA - skeletal muscle [nTPM]":"36.5","Tissue RNA - skin 1 [nTPM]":"3.0","Tissue RNA - small intestine [nTPM]":"6.9","Tissue RNA - smooth muscle [nTPM]":"25.4","Tissue RNA - spinal cord [nTPM]":"2.4","Tissue RNA - spleen [nTPM]":"1.7","Tissue RNA - stomach 1 [nTPM]":"15.0","Tissue RNA - testis [nTPM]":"3.5","Tissue RNA - thalamus [nTPM]":"4.7","Tissue RNA - thymus [nTPM]":"2.6","Tissue RNA - thyroid gland [nTPM]":"7.6","Tissue RNA - tongue [nTPM]":"16.5","Tissue RNA - tonsil [nTPM]":"1.2","Tissue RNA - urinary bladder [nTPM]":"18.1","Tissue RNA - vagina [nTPM]":"6.8","Tissue RNA - white matter [nTPM]":"8.4","Cell RNA - A-431 [nTPM]":"29.3","Cell RNA - A549 [nTPM]":"24.6","Cell RNA - AF22 [nTPM]":"6.8","Cell RNA - AN3-CA [nTPM]":"33.4","Cell RNA - ASC diff [nTPM]":"30.1","Cell RNA - ASC TERT1 [nTPM]":"5.8","Cell RNA - BEWO [nTPM]":"0.6","Cell RNA - BJ [nTPM]":"40.5","Cell RNA - BJ hTERT+ [nTPM]":"24.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"51.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"48.5","Cell RNA - CACO-2 [nTPM]":"16.4","Cell RNA - CAPAN-2 [nTPM]":"34.6","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"5.9","Cell RNA - fHDF\/TERT166 [nTPM]":"66.4","Cell RNA - GAMG [nTPM]":"74.5","Cell RNA - HaCaT [nTPM]":"7.1","Cell RNA - HAP1 [nTPM]":"17.3","Cell RNA - HBEC3-KT [nTPM]":"12.3","Cell RNA - HBF TERT88 [nTPM]":"28.6","Cell RNA - HDLM-2 [nTPM]":"19.1","Cell RNA - HEK 293 [nTPM]":"10.4","Cell RNA - HEL [nTPM]":"67.1","Cell RNA - HeLa [nTPM]":"18.4","Cell RNA - Hep G2 [nTPM]":"45.6","Cell RNA - HHSteC [nTPM]":"39.0","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"4.8","Cell RNA - HSkMC [nTPM]":"14.0","Cell RNA - hTCEpi [nTPM]":"17.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"29.9","Cell RNA - hTERT-HME1 [nTPM]":"11.6","Cell RNA - hTERT-RPE1 [nTPM]":"39.8","Cell RNA - HUVEC TERT2 [nTPM]":"10.1","Cell RNA - JURKAT [nTPM]":"35.1","Cell RNA - K-562 [nTPM]":"0.6","Cell RNA - Karpas-707 [nTPM]":"1.3","Cell RNA - LHCN-M2 [nTPM]":"69.0","Cell RNA - MCF7 [nTPM]":"21.0","Cell RNA - MOLT-4 [nTPM]":"50.4","Cell RNA - NB-4 [nTPM]":"6.7","Cell RNA - NTERA-2 [nTPM]":"14.6","Cell RNA - OE19 [nTPM]":"2.2","Cell RNA - PC-3 [nTPM]":"6.6","Cell RNA - REH [nTPM]":"44.7","Cell RNA - RH-30 [nTPM]":"7.1","Cell RNA - RPMI-8226 [nTPM]":"0.8","Cell RNA - RPTEC TERT1 [nTPM]":"20.5","Cell RNA - RT4 [nTPM]":"5.6","Cell RNA - SCLC-21H [nTPM]":"7.5","Cell RNA - SH-SY5Y [nTPM]":"19.1","Cell RNA - SiHa [nTPM]":"34.6","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"58.9","Cell RNA - SuSa [nTPM]":"21.2","Cell RNA - T-47d [nTPM]":"24.2","Cell RNA - THP-1 [nTPM]":"16.7","Cell RNA - TIME [nTPM]":"9.8","Cell RNA - U-138 MG [nTPM]":"30.3","Cell RNA - U-2 OS [nTPM]":"17.4","Cell RNA - U-2197 [nTPM]":"18.7","Cell RNA - U-251 MG [nTPM]":"18.8","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"0.8","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"22.3","Cell RNA - U-937 [nTPM]":"7.7","Cell RNA - WM-115 [nTPM]":"4.3","Blood RNA - basophil [nTPM]":"4.7","Blood RNA - classical monocyte [nTPM]":"0.9","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"1.2","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"5.0","Blood RNA - memory CD8 T-cell [nTPM]":"1.0","Blood RNA - myeloid DC [nTPM]":"3.0","Blood RNA - naive B-cell [nTPM]":"1.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.9","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"2.6","Blood RNA - NK-cell [nTPM]":"3.3","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"55.7","Blood RNA - total PBMC [nTPM]":"1.3","Brain RNA - amygdala [nTPM]":"3.1","Brain RNA - basal ganglia [nTPM]":"3.5","Brain RNA - cerebellum [nTPM]":"10.7","Brain RNA - cerebral cortex [nTPM]":"4.6","Brain RNA - hippocampal formation [nTPM]":"3.0","Brain RNA - hypothalamus [nTPM]":"6.5","Brain RNA - medulla oblongata [nTPM]":"5.5","Brain RNA - midbrain [nTPM]":"5.2","Brain RNA - pons [nTPM]":"5.0","Brain RNA - spinal cord [nTPM]":"2.4","Brain RNA - thalamus [nTPM]":"4.7","Brain RNA - white matter [nTPM]":"8.4","Single Cell Type RNA - Adipocytes [nTPM]":"2.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"143.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"2.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"4.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"16.5","Single Cell Type RNA - Early spermatids [nTPM]":"11.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.0","Single Cell Type RNA - Endothelial cells [nTPM]":"5.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"29.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.9","Single Cell Type RNA - Fibroblasts [nTPM]":"7.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.4","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"17.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.7","Single Cell Type RNA - Hepatocytes [nTPM]":"1.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.2","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.7","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"3.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"0.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"31.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.5","Single Cell Type RNA - Spermatocytes [nTPM]":"7.4","Single Cell Type RNA - Spermatogonia [nTPM]":"5.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.0","Single Cell Type RNA - T-cells [nTPM]":"2.9","Single Cell Type RNA - Theca cells [nTPM]":"10.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.5","Single Cell Type RNA - Urothelial cells [nTPM]":"6.2"},{"Gene":"HACE1","Gene synonym":["KIAA1320"],"Ensembl":"ENSG00000085382","Gene description":"HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1","Uniprot":["Q8IYU2"],"Chromosome":"6","Position":"104728094-104859919","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"30.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"45.9","Excitatory neurons":"118.8","Inhibitory neurons":"84.2","Microglial cells":"45.9","Oligodendrocyte precursor cells":"64.3","Oligodendrocytes":"74.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046071"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA046071":"AB_2679524"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.17e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.50e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.7","Tissue RNA - adrenal gland [nTPM]":"3.2","Tissue RNA - amygdala [nTPM]":"2.7","Tissue RNA - appendix [nTPM]":"2.2","Tissue RNA - basal ganglia [nTPM]":"4.4","Tissue RNA - bone marrow [nTPM]":"2.9","Tissue RNA - breast [nTPM]":"3.1","Tissue RNA - cerebellum [nTPM]":"5.0","Tissue RNA - cerebral cortex [nTPM]":"4.8","Tissue RNA - cervix [nTPM]":"3.9","Tissue RNA - choroid plexus [nTPM]":"0.4","Tissue RNA - colon [nTPM]":"2.6","Tissue RNA - duodenum [nTPM]":"2.1","Tissue RNA - endometrium 1 [nTPM]":"3.9","Tissue RNA - epididymis [nTPM]":"1.1","Tissue RNA - esophagus [nTPM]":"5.3","Tissue RNA - fallopian tube [nTPM]":"3.3","Tissue RNA - gallbladder [nTPM]":"3.1","Tissue RNA - heart muscle [nTPM]":"3.3","Tissue RNA - hippocampal formation [nTPM]":"3.1","Tissue RNA - hypothalamus [nTPM]":"2.5","Tissue RNA - kidney [nTPM]":"6.2","Tissue RNA - liver [nTPM]":"1.6","Tissue RNA - lung [nTPM]":"3.6","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"1.9","Tissue RNA - midbrain [nTPM]":"2.6","Tissue RNA - ovary [nTPM]":"3.8","Tissue RNA - pancreas [nTPM]":"1.9","Tissue RNA - parathyroid gland [nTPM]":"7.2","Tissue RNA - pituitary gland [nTPM]":"1.5","Tissue RNA - placenta [nTPM]":"30.6","Tissue RNA - pons [nTPM]":"2.3","Tissue RNA - prostate [nTPM]":"3.7","Tissue RNA - rectum [nTPM]":"1.8","Tissue RNA - retina [nTPM]":"11.5","Tissue RNA - salivary gland [nTPM]":"2.9","Tissue RNA - seminal vesicle [nTPM]":"4.1","Tissue RNA - skeletal muscle [nTPM]":"2.2","Tissue RNA - skin 1 [nTPM]":"2.5","Tissue RNA - small intestine [nTPM]":"2.1","Tissue RNA - smooth muscle [nTPM]":"4.0","Tissue RNA - spinal cord [nTPM]":"1.4","Tissue RNA - spleen [nTPM]":"2.5","Tissue RNA - stomach 1 [nTPM]":"2.4","Tissue RNA - testis [nTPM]":"10.4","Tissue RNA - thalamus [nTPM]":"3.1","Tissue RNA - thymus [nTPM]":"3.9","Tissue RNA - thyroid gland [nTPM]":"4.5","Tissue RNA - tongue [nTPM]":"4.1","Tissue RNA - tonsil [nTPM]":"2.4","Tissue RNA - urinary bladder [nTPM]":"3.3","Tissue RNA - vagina [nTPM]":"2.9","Tissue RNA - white matter [nTPM]":"5.8","Cell RNA - A-431 [nTPM]":"3.9","Cell RNA - A549 [nTPM]":"2.7","Cell RNA - AF22 [nTPM]":"11.3","Cell RNA - AN3-CA [nTPM]":"14.3","Cell RNA - ASC diff [nTPM]":"6.6","Cell RNA - ASC TERT1 [nTPM]":"8.8","Cell RNA - BEWO [nTPM]":"13.3","Cell RNA - BJ [nTPM]":"7.7","Cell RNA - BJ hTERT+ [nTPM]":"11.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.2","Cell RNA - CACO-2 [nTPM]":"2.5","Cell RNA - CAPAN-2 [nTPM]":"2.3","Cell RNA - Daudi [nTPM]":"2.2","Cell RNA - EFO-21 [nTPM]":"3.4","Cell RNA - fHDF\/TERT166 [nTPM]":"5.9","Cell RNA - GAMG [nTPM]":"8.1","Cell RNA - HaCaT [nTPM]":"2.6","Cell RNA - HAP1 [nTPM]":"2.8","Cell RNA - HBEC3-KT [nTPM]":"5.3","Cell RNA - HBF TERT88 [nTPM]":"10.0","Cell RNA - HDLM-2 [nTPM]":"9.1","Cell RNA - HEK 293 [nTPM]":"7.2","Cell RNA - HEL [nTPM]":"7.7","Cell RNA - HeLa [nTPM]":"2.5","Cell RNA - Hep G2 [nTPM]":"3.4","Cell RNA - HHSteC [nTPM]":"6.6","Cell RNA - HL-60 [nTPM]":"6.8","Cell RNA - HMC-1 [nTPM]":"2.5","Cell RNA - HSkMC [nTPM]":"5.9","Cell RNA - hTCEpi [nTPM]":"4.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.2","Cell RNA - hTERT-HME1 [nTPM]":"5.2","Cell RNA - hTERT-RPE1 [nTPM]":"6.3","Cell RNA - HUVEC TERT2 [nTPM]":"8.0","Cell RNA - JURKAT [nTPM]":"9.2","Cell RNA - K-562 [nTPM]":"7.6","Cell RNA - Karpas-707 [nTPM]":"2.4","Cell RNA - LHCN-M2 [nTPM]":"9.6","Cell RNA - MCF7 [nTPM]":"2.8","Cell RNA - MOLT-4 [nTPM]":"5.1","Cell RNA - NB-4 [nTPM]":"4.1","Cell RNA - NTERA-2 [nTPM]":"5.0","Cell RNA - OE19 [nTPM]":"2.9","Cell RNA - PC-3 [nTPM]":"2.6","Cell RNA - REH [nTPM]":"8.0","Cell RNA - RH-30 [nTPM]":"12.8","Cell RNA - RPMI-8226 [nTPM]":"0.9","Cell RNA - RPTEC TERT1 [nTPM]":"3.8","Cell RNA - RT4 [nTPM]":"6.6","Cell RNA - SCLC-21H [nTPM]":"6.1","Cell RNA - SH-SY5Y [nTPM]":"9.1","Cell RNA - SiHa [nTPM]":"4.2","Cell RNA - SK-BR-3 [nTPM]":"4.3","Cell RNA - SK-MEL-30 [nTPM]":"2.3","Cell RNA - SuSa [nTPM]":"7.3","Cell RNA - T-47d [nTPM]":"2.7","Cell RNA - THP-1 [nTPM]":"9.2","Cell RNA - TIME [nTPM]":"8.5","Cell RNA - U-138 MG [nTPM]":"3.9","Cell RNA - U-2 OS [nTPM]":"3.2","Cell RNA - U-2197 [nTPM]":"10.5","Cell RNA - U-251 MG [nTPM]":"7.4","Cell RNA - U-266\/70 [nTPM]":"3.5","Cell RNA - U-266\/84 [nTPM]":"4.1","Cell RNA - U-698 [nTPM]":"7.6","Cell RNA - U-87 MG [nTPM]":"4.0","Cell RNA - U-937 [nTPM]":"6.4","Cell RNA - WM-115 [nTPM]":"7.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"1.2","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"1.3","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"0.8","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"2.7","Brain RNA - basal ganglia [nTPM]":"4.4","Brain RNA - cerebellum [nTPM]":"5.0","Brain RNA - cerebral cortex [nTPM]":"4.8","Brain RNA - hippocampal formation [nTPM]":"3.1","Brain RNA - hypothalamus [nTPM]":"2.5","Brain RNA - medulla oblongata [nTPM]":"1.9","Brain RNA - midbrain [nTPM]":"2.6","Brain RNA - pons [nTPM]":"2.3","Brain RNA - spinal cord [nTPM]":"1.4","Brain RNA - thalamus [nTPM]":"3.1","Brain RNA - white matter [nTPM]":"5.8","Single Cell Type RNA - Adipocytes [nTPM]":"11.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"42.4","Single Cell Type RNA - B-cells [nTPM]":"5.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"11.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"3.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.6","Single Cell Type RNA - dendritic cells [nTPM]":"4.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.6","Single Cell Type RNA - Early spermatids [nTPM]":"6.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.2","Single Cell Type RNA - Endothelial cells [nTPM]":"12.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"3.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"118.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.4","Single Cell Type RNA - Fibroblasts [nTPM]":"7.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.4","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"7.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.2","Single Cell Type RNA - Hepatocytes [nTPM]":"2.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.7","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"84.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.1","Single Cell Type RNA - Langerhans cells [nTPM]":"2.4","Single Cell Type RNA - Late spermatids [nTPM]":"4.6","Single Cell Type RNA - Leydig cells [nTPM]":"6.2","Single Cell Type RNA - Macrophages [nTPM]":"3.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"45.9","Single Cell Type RNA - monocytes [nTPM]":"4.3","Single Cell Type RNA - Muller glia cells [nTPM]":"6.1","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"64.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"74.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.4","Single Cell Type RNA - Paneth cells [nTPM]":"2.9","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"3.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"31.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.6","Single Cell Type RNA - Spermatocytes [nTPM]":"13.2","Single Cell Type RNA - Spermatogonia [nTPM]":"3.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.3","Single Cell Type RNA - T-cells [nTPM]":"6.2","Single Cell Type RNA - Theca cells [nTPM]":"2.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.9","Single Cell Type RNA - Urothelial cells [nTPM]":"1.9"},{"Gene":"HADHA","Gene synonym":["GBP","LCEH","LCHAD","MTPA"],"Ensembl":"ENSG00000084754","Gene description":"Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha","Uniprot":["P40939"],"Chromosome":"2","Position":"26190635-26244672","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Lyase","Multifunctional enzyme","Oxidoreductase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"502.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"527.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015536","HPA056070"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"470000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA015536":"AB_1850473","HPA056070":"AB_2683026"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.68e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Tissue RNA - adipose tissue [nTPM]":"105.0","Tissue RNA - adrenal gland [nTPM]":"125.3","Tissue RNA - amygdala [nTPM]":"57.7","Tissue RNA - appendix [nTPM]":"31.1","Tissue RNA - basal ganglia [nTPM]":"60.7","Tissue RNA - bone marrow [nTPM]":"46.3","Tissue RNA - breast [nTPM]":"94.9","Tissue RNA - cerebellum [nTPM]":"65.0","Tissue RNA - cerebral cortex [nTPM]":"69.6","Tissue RNA - cervix [nTPM]":"72.6","Tissue RNA - choroid plexus [nTPM]":"59.1","Tissue RNA - colon [nTPM]":"108.4","Tissue RNA - duodenum [nTPM]":"115.0","Tissue RNA - endometrium 1 [nTPM]":"61.8","Tissue RNA - epididymis [nTPM]":"30.7","Tissue RNA - esophagus [nTPM]":"90.1","Tissue RNA - fallopian tube [nTPM]":"60.1","Tissue RNA - gallbladder [nTPM]":"32.4","Tissue RNA - heart muscle [nTPM]":"330.2","Tissue RNA - hippocampal formation [nTPM]":"52.8","Tissue RNA - hypothalamus [nTPM]":"61.9","Tissue RNA - kidney [nTPM]":"99.0","Tissue RNA - liver [nTPM]":"156.7","Tissue RNA - lung [nTPM]":"66.9","Tissue RNA - lymph node [nTPM]":"35.3","Tissue RNA - medulla oblongata [nTPM]":"64.4","Tissue RNA - midbrain [nTPM]":"62.2","Tissue RNA - ovary [nTPM]":"77.8","Tissue RNA - pancreas [nTPM]":"101.4","Tissue RNA - parathyroid gland [nTPM]":"95.0","Tissue RNA - pituitary gland [nTPM]":"57.4","Tissue RNA - placenta [nTPM]":"39.2","Tissue RNA - pons [nTPM]":"64.2","Tissue RNA - prostate [nTPM]":"60.2","Tissue RNA - rectum [nTPM]":"76.1","Tissue RNA - retina [nTPM]":"14.9","Tissue RNA - salivary gland [nTPM]":"77.9","Tissue RNA - seminal vesicle [nTPM]":"33.4","Tissue RNA - skeletal muscle [nTPM]":"502.5","Tissue RNA - skin 1 [nTPM]":"95.7","Tissue RNA - small intestine [nTPM]":"106.2","Tissue RNA - smooth muscle [nTPM]":"57.4","Tissue RNA - spinal cord [nTPM]":"61.8","Tissue RNA - spleen [nTPM]":"68.4","Tissue RNA - stomach 1 [nTPM]":"93.8","Tissue RNA - testis [nTPM]":"49.0","Tissue RNA - thalamus [nTPM]":"62.4","Tissue RNA - thymus [nTPM]":"46.7","Tissue RNA - thyroid gland [nTPM]":"59.5","Tissue RNA - tongue [nTPM]":"300.7","Tissue RNA - tonsil [nTPM]":"58.5","Tissue RNA - urinary bladder [nTPM]":"79.1","Tissue RNA - vagina [nTPM]":"73.6","Tissue RNA - white matter [nTPM]":"67.2","Cell RNA - A-431 [nTPM]":"105.7","Cell RNA - A549 [nTPM]":"88.1","Cell RNA - AF22 [nTPM]":"58.4","Cell RNA - AN3-CA [nTPM]":"90.8","Cell RNA - ASC diff [nTPM]":"221.1","Cell RNA - ASC TERT1 [nTPM]":"139.9","Cell RNA - BEWO [nTPM]":"51.5","Cell RNA - BJ [nTPM]":"80.6","Cell RNA - BJ hTERT+ [nTPM]":"84.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"78.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"67.7","Cell RNA - CACO-2 [nTPM]":"114.7","Cell RNA - CAPAN-2 [nTPM]":"104.1","Cell RNA - Daudi [nTPM]":"71.7","Cell RNA - EFO-21 [nTPM]":"50.2","Cell RNA - fHDF\/TERT166 [nTPM]":"138.4","Cell RNA - GAMG [nTPM]":"78.6","Cell RNA - HaCaT [nTPM]":"66.8","Cell RNA - HAP1 [nTPM]":"103.4","Cell RNA - HBEC3-KT [nTPM]":"152.6","Cell RNA - HBF TERT88 [nTPM]":"72.5","Cell RNA - HDLM-2 [nTPM]":"139.1","Cell RNA - HEK 293 [nTPM]":"103.6","Cell RNA - HEL [nTPM]":"103.3","Cell RNA - HeLa [nTPM]":"86.2","Cell RNA - Hep G2 [nTPM]":"197.9","Cell RNA - HHSteC [nTPM]":"73.3","Cell RNA - HL-60 [nTPM]":"132.2","Cell RNA - HMC-1 [nTPM]":"69.2","Cell RNA - HSkMC [nTPM]":"142.7","Cell RNA - hTCEpi [nTPM]":"101.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"112.4","Cell RNA - hTERT-HME1 [nTPM]":"109.3","Cell RNA - hTERT-RPE1 [nTPM]":"82.8","Cell RNA - HUVEC TERT2 [nTPM]":"127.7","Cell RNA - JURKAT [nTPM]":"70.4","Cell RNA - K-562 [nTPM]":"140.2","Cell RNA - Karpas-707 [nTPM]":"133.2","Cell RNA - LHCN-M2 [nTPM]":"101.1","Cell RNA - MCF7 [nTPM]":"128.2","Cell RNA - MOLT-4 [nTPM]":"63.4","Cell RNA - NB-4 [nTPM]":"137.7","Cell RNA - NTERA-2 [nTPM]":"50.1","Cell RNA - OE19 [nTPM]":"77.5","Cell RNA - PC-3 [nTPM]":"134.1","Cell RNA - REH [nTPM]":"52.9","Cell RNA - RH-30 [nTPM]":"128.5","Cell RNA - RPMI-8226 [nTPM]":"143.7","Cell RNA - RPTEC TERT1 [nTPM]":"90.3","Cell RNA - RT4 [nTPM]":"125.3","Cell RNA - SCLC-21H [nTPM]":"41.9","Cell RNA - SH-SY5Y [nTPM]":"85.1","Cell RNA - SiHa [nTPM]":"94.6","Cell RNA - SK-BR-3 [nTPM]":"104.6","Cell RNA - SK-MEL-30 [nTPM]":"102.4","Cell RNA - SuSa [nTPM]":"44.5","Cell RNA - T-47d [nTPM]":"52.2","Cell RNA - THP-1 [nTPM]":"125.8","Cell RNA - TIME [nTPM]":"127.1","Cell RNA - U-138 MG [nTPM]":"48.8","Cell RNA - U-2 OS [nTPM]":"70.7","Cell RNA - U-2197 [nTPM]":"69.9","Cell RNA - U-251 MG [nTPM]":"58.0","Cell RNA - U-266\/70 [nTPM]":"44.8","Cell RNA - U-266\/84 [nTPM]":"86.5","Cell RNA - U-698 [nTPM]":"113.4","Cell RNA - U-87 MG [nTPM]":"77.6","Cell RNA - U-937 [nTPM]":"150.2","Cell RNA - WM-115 [nTPM]":"56.2","Blood RNA - basophil [nTPM]":"22.5","Blood RNA - classical monocyte [nTPM]":"84.0","Blood RNA - eosinophil [nTPM]":"33.5","Blood RNA - gdT-cell [nTPM]":"31.8","Blood RNA - intermediate monocyte [nTPM]":"92.3","Blood RNA - MAIT T-cell [nTPM]":"39.1","Blood RNA - memory B-cell [nTPM]":"40.5","Blood RNA - memory CD4 T-cell [nTPM]":"36.8","Blood RNA - memory CD8 T-cell [nTPM]":"38.7","Blood RNA - myeloid DC [nTPM]":"80.8","Blood RNA - naive B-cell [nTPM]":"31.2","Blood RNA - naive CD4 T-cell [nTPM]":"42.6","Blood RNA - naive CD8 T-cell [nTPM]":"40.1","Blood RNA - neutrophil [nTPM]":"20.9","Blood RNA - NK-cell [nTPM]":"38.8","Blood RNA - non-classical monocyte [nTPM]":"86.1","Blood RNA - plasmacytoid DC [nTPM]":"31.3","Blood RNA - T-reg [nTPM]":"50.9","Blood RNA - total PBMC [nTPM]":"89.9","Brain RNA - amygdala [nTPM]":"57.7","Brain RNA - basal ganglia [nTPM]":"60.7","Brain RNA - cerebellum [nTPM]":"65.0","Brain RNA - cerebral cortex [nTPM]":"69.6","Brain RNA - hippocampal formation [nTPM]":"52.8","Brain RNA - hypothalamus [nTPM]":"61.9","Brain RNA - medulla oblongata [nTPM]":"64.4","Brain RNA - midbrain [nTPM]":"62.2","Brain RNA - pons [nTPM]":"64.2","Brain RNA - spinal cord [nTPM]":"61.8","Brain RNA - thalamus [nTPM]":"62.4","Brain RNA - white matter [nTPM]":"67.2","Single Cell Type RNA - Adipocytes [nTPM]":"122.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"89.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"99.0","Single Cell Type RNA - Astrocytes [nTPM]":"47.0","Single Cell Type RNA - B-cells [nTPM]":"101.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"89.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"137.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"139.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"97.3","Single Cell Type RNA - Bipolar cells [nTPM]":"35.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"89.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"96.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"349.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"82.9","Single Cell Type RNA - Club cells [nTPM]":"128.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"77.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"182.0","Single Cell Type RNA - dendritic cells [nTPM]":"95.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"242.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"131.0","Single Cell Type RNA - Ductal cells [nTPM]":"120.8","Single Cell Type RNA - Early spermatids [nTPM]":"39.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"73.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"121.1","Single Cell Type RNA - Endothelial cells [nTPM]":"99.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"91.4","Single Cell Type RNA - Erythroid cells [nTPM]":"155.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"108.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"94.7","Single Cell Type RNA - Fibroblasts [nTPM]":"96.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"100.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"85.5","Single Cell Type RNA - granulocytes [nTPM]":"139.9","Single Cell Type RNA - Granulosa cells [nTPM]":"140.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"84.3","Single Cell Type RNA - Hepatocytes [nTPM]":"185.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"163.0","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"28.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"156.5","Single Cell Type RNA - Ionocytes [nTPM]":"89.5","Single Cell Type RNA - Kupffer cells [nTPM]":"136.8","Single Cell Type RNA - Langerhans cells [nTPM]":"106.0","Single Cell Type RNA - Late spermatids [nTPM]":"74.3","Single Cell Type RNA - Leydig cells [nTPM]":"92.6","Single Cell Type RNA - Macrophages [nTPM]":"145.0","Single Cell Type RNA - Melanocytes [nTPM]":"81.8","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"170.7","Single Cell Type RNA - Muller glia cells [nTPM]":"65.4","Single Cell Type RNA - NK-cells [nTPM]":"93.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"30.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"37.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"90.0","Single Cell Type RNA - Paneth cells [nTPM]":"195.6","Single Cell Type RNA - Peritubular cells [nTPM]":"84.2","Single Cell Type RNA - Plasma cells [nTPM]":"90.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"76.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"527.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"182.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"84.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"62.3","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"129.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"109.6","Single Cell Type RNA - Spermatocytes [nTPM]":"147.9","Single Cell Type RNA - Spermatogonia [nTPM]":"54.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"136.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"103.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"129.2","Single Cell Type RNA - T-cells [nTPM]":"100.5","Single Cell Type RNA - Theca cells [nTPM]":"154.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"216.7","Single Cell Type RNA - Urothelial cells [nTPM]":"104.4"},{"Gene":"HADHB","Gene synonym":["MTPB"],"Ensembl":"ENSG00000138029","Gene description":"Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta","Uniprot":["P55084"],"Chromosome":"2","Position":"26243170-26290465","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"793.3","skeletal muscle":"950.6","tongue":"1097.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"1167.5","Distal tubular cells":"520.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037539","HPA037540","HPA066099"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"61000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA037539":"AB_10671374","HPA037540":"AB_2675531","HPA066099":"AB_2685618"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.37e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.68e-2"},"Tissue RNA - adipose tissue [nTPM]":"127.0","Tissue RNA - adrenal gland [nTPM]":"224.7","Tissue RNA - amygdala [nTPM]":"120.6","Tissue RNA - appendix [nTPM]":"51.1","Tissue RNA - basal ganglia [nTPM]":"135.4","Tissue RNA - bone marrow [nTPM]":"58.8","Tissue RNA - breast [nTPM]":"91.3","Tissue RNA - cerebellum [nTPM]":"146.4","Tissue RNA - cerebral cortex [nTPM]":"138.1","Tissue RNA - cervix [nTPM]":"65.2","Tissue RNA - choroid plexus [nTPM]":"128.0","Tissue RNA - colon [nTPM]":"110.7","Tissue RNA - duodenum [nTPM]":"224.2","Tissue RNA - endometrium 1 [nTPM]":"55.9","Tissue RNA - epididymis [nTPM]":"73.7","Tissue RNA - esophagus [nTPM]":"101.3","Tissue RNA - fallopian tube [nTPM]":"68.8","Tissue RNA - gallbladder [nTPM]":"64.3","Tissue RNA - heart muscle [nTPM]":"793.3","Tissue RNA - hippocampal formation [nTPM]":"109.0","Tissue RNA - hypothalamus [nTPM]":"138.1","Tissue RNA - kidney [nTPM]":"231.4","Tissue RNA - liver [nTPM]":"324.8","Tissue RNA - lung [nTPM]":"64.7","Tissue RNA - lymph node [nTPM]":"54.9","Tissue RNA - medulla oblongata [nTPM]":"135.9","Tissue RNA - midbrain [nTPM]":"141.6","Tissue RNA - ovary [nTPM]":"78.4","Tissue RNA - pancreas [nTPM]":"83.7","Tissue RNA - parathyroid gland [nTPM]":"209.5","Tissue RNA - pituitary gland [nTPM]":"48.1","Tissue RNA - placenta [nTPM]":"65.6","Tissue RNA - pons [nTPM]":"139.6","Tissue RNA - prostate [nTPM]":"77.1","Tissue RNA - rectum [nTPM]":"113.2","Tissue RNA - retina [nTPM]":"63.0","Tissue RNA - salivary gland [nTPM]":"104.8","Tissue RNA - seminal vesicle [nTPM]":"75.0","Tissue RNA - skeletal muscle [nTPM]":"950.6","Tissue RNA - skin 1 [nTPM]":"74.4","Tissue RNA - small intestine [nTPM]":"184.4","Tissue RNA - smooth muscle [nTPM]":"79.0","Tissue RNA - spinal cord [nTPM]":"141.4","Tissue RNA - spleen [nTPM]":"75.8","Tissue RNA - stomach 1 [nTPM]":"109.0","Tissue RNA - testis [nTPM]":"67.1","Tissue RNA - thalamus [nTPM]":"143.3","Tissue RNA - thymus [nTPM]":"53.1","Tissue RNA - thyroid gland [nTPM]":"90.8","Tissue RNA - tongue [nTPM]":"1097.1","Tissue RNA - tonsil [nTPM]":"62.5","Tissue RNA - urinary bladder [nTPM]":"89.2","Tissue RNA - vagina [nTPM]":"64.1","Tissue RNA - white matter [nTPM]":"152.8","Cell RNA - A-431 [nTPM]":"108.2","Cell RNA - A549 [nTPM]":"83.2","Cell RNA - AF22 [nTPM]":"56.6","Cell RNA - AN3-CA [nTPM]":"102.2","Cell RNA - ASC diff [nTPM]":"342.1","Cell RNA - ASC TERT1 [nTPM]":"190.1","Cell RNA - BEWO [nTPM]":"57.9","Cell RNA - BJ [nTPM]":"89.0","Cell RNA - BJ hTERT+ [nTPM]":"134.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"89.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"86.8","Cell RNA - CACO-2 [nTPM]":"100.5","Cell RNA - CAPAN-2 [nTPM]":"101.7","Cell RNA - Daudi [nTPM]":"53.9","Cell RNA - EFO-21 [nTPM]":"60.8","Cell RNA - fHDF\/TERT166 [nTPM]":"145.3","Cell RNA - GAMG [nTPM]":"100.1","Cell RNA - HaCaT [nTPM]":"82.8","Cell RNA - HAP1 [nTPM]":"95.2","Cell RNA - HBEC3-KT [nTPM]":"124.8","Cell RNA - HBF TERT88 [nTPM]":"109.2","Cell RNA - HDLM-2 [nTPM]":"121.1","Cell RNA - HEK 293 [nTPM]":"83.1","Cell RNA - HEL [nTPM]":"123.6","Cell RNA - HeLa [nTPM]":"44.9","Cell RNA - Hep G2 [nTPM]":"194.2","Cell RNA - HHSteC [nTPM]":"145.9","Cell RNA - HL-60 [nTPM]":"100.6","Cell RNA - HMC-1 [nTPM]":"90.0","Cell RNA - HSkMC [nTPM]":"183.7","Cell RNA - hTCEpi [nTPM]":"201.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"92.7","Cell RNA - hTERT-HME1 [nTPM]":"149.0","Cell RNA - hTERT-RPE1 [nTPM]":"151.0","Cell RNA - HUVEC TERT2 [nTPM]":"168.2","Cell RNA - JURKAT [nTPM]":"81.0","Cell RNA - K-562 [nTPM]":"105.2","Cell RNA - Karpas-707 [nTPM]":"83.9","Cell RNA - LHCN-M2 [nTPM]":"189.5","Cell RNA - MCF7 [nTPM]":"78.0","Cell RNA - MOLT-4 [nTPM]":"57.1","Cell RNA - NB-4 [nTPM]":"190.7","Cell RNA - NTERA-2 [nTPM]":"39.8","Cell RNA - OE19 [nTPM]":"160.2","Cell RNA - PC-3 [nTPM]":"89.0","Cell RNA - REH [nTPM]":"61.7","Cell RNA - RH-30 [nTPM]":"188.3","Cell RNA - RPMI-8226 [nTPM]":"103.2","Cell RNA - RPTEC TERT1 [nTPM]":"183.3","Cell RNA - RT4 [nTPM]":"148.9","Cell RNA - SCLC-21H [nTPM]":"27.2","Cell RNA - SH-SY5Y [nTPM]":"93.7","Cell RNA - SiHa [nTPM]":"151.7","Cell RNA - SK-BR-3 [nTPM]":"169.8","Cell RNA - SK-MEL-30 [nTPM]":"239.5","Cell RNA - SuSa [nTPM]":"68.5","Cell RNA - T-47d [nTPM]":"105.4","Cell RNA - THP-1 [nTPM]":"177.9","Cell RNA - TIME [nTPM]":"118.0","Cell RNA - U-138 MG [nTPM]":"83.5","Cell RNA - U-2 OS [nTPM]":"86.9","Cell RNA - U-2197 [nTPM]":"79.3","Cell RNA - U-251 MG [nTPM]":"65.1","Cell RNA - U-266\/70 [nTPM]":"62.6","Cell RNA - U-266\/84 [nTPM]":"101.1","Cell RNA - U-698 [nTPM]":"94.7","Cell RNA - U-87 MG [nTPM]":"95.5","Cell RNA - U-937 [nTPM]":"158.4","Cell RNA - WM-115 [nTPM]":"84.4","Blood RNA - basophil [nTPM]":"95.7","Blood RNA - classical monocyte [nTPM]":"168.1","Blood RNA - eosinophil [nTPM]":"66.4","Blood RNA - gdT-cell [nTPM]":"45.2","Blood RNA - intermediate monocyte [nTPM]":"150.3","Blood RNA - MAIT T-cell [nTPM]":"57.6","Blood RNA - memory B-cell [nTPM]":"65.5","Blood RNA - memory CD4 T-cell [nTPM]":"61.3","Blood RNA - memory CD8 T-cell [nTPM]":"56.6","Blood RNA - myeloid DC [nTPM]":"154.2","Blood RNA - naive B-cell [nTPM]":"49.7","Blood RNA - naive CD4 T-cell [nTPM]":"55.8","Blood RNA - naive CD8 T-cell [nTPM]":"51.3","Blood RNA - neutrophil [nTPM]":"72.7","Blood RNA - NK-cell [nTPM]":"88.2","Blood RNA - non-classical monocyte [nTPM]":"123.3","Blood RNA - plasmacytoid DC [nTPM]":"51.8","Blood RNA - T-reg [nTPM]":"94.7","Blood RNA - total PBMC [nTPM]":"135.6","Brain RNA - amygdala [nTPM]":"120.6","Brain RNA - basal ganglia [nTPM]":"135.4","Brain RNA - cerebellum [nTPM]":"146.4","Brain RNA - cerebral cortex [nTPM]":"138.1","Brain RNA - hippocampal formation [nTPM]":"109.0","Brain RNA - hypothalamus [nTPM]":"138.1","Brain RNA - medulla oblongata [nTPM]":"135.9","Brain RNA - midbrain [nTPM]":"141.6","Brain RNA - pons [nTPM]":"139.6","Brain RNA - spinal cord [nTPM]":"141.4","Brain RNA - thalamus [nTPM]":"143.3","Brain RNA - white matter [nTPM]":"152.8","Single Cell Type RNA - Adipocytes [nTPM]":"106.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"36.5","Single Cell Type RNA - Astrocytes [nTPM]":"63.0","Single Cell Type RNA - B-cells [nTPM]":"48.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"62.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"136.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"183.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"49.5","Single Cell Type RNA - Bipolar cells [nTPM]":"29.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"49.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"52.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1167.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"104.4","Single Cell Type RNA - Club cells [nTPM]":"107.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"97.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"56.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"227.9","Single Cell Type RNA - dendritic cells [nTPM]":"42.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"129.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"520.4","Single Cell Type RNA - Ductal cells [nTPM]":"124.0","Single Cell Type RNA - Early spermatids [nTPM]":"93.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"59.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"49.0","Single Cell Type RNA - Endothelial cells [nTPM]":"75.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"74.9","Single Cell Type RNA - Erythroid cells [nTPM]":"85.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"32.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"57.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"75.2","Single Cell Type RNA - Fibroblasts [nTPM]":"79.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"53.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"60.2","Single Cell Type RNA - granulocytes [nTPM]":"62.8","Single Cell Type RNA - Granulosa cells [nTPM]":"94.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"69.9","Single Cell Type RNA - Hepatocytes [nTPM]":"277.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"139.6","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"33.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"93.4","Single Cell Type RNA - Ionocytes [nTPM]":"114.0","Single Cell Type RNA - Kupffer cells [nTPM]":"98.1","Single Cell Type RNA - Langerhans cells [nTPM]":"67.4","Single Cell Type RNA - Late spermatids [nTPM]":"99.7","Single Cell Type RNA - Leydig cells [nTPM]":"56.5","Single Cell Type RNA - Macrophages [nTPM]":"78.1","Single Cell Type RNA - Melanocytes [nTPM]":"88.9","Single Cell Type RNA - Microglial cells [nTPM]":"27.2","Single Cell Type RNA - monocytes [nTPM]":"110.2","Single Cell Type RNA - Muller glia cells [nTPM]":"65.0","Single Cell Type RNA - NK-cells [nTPM]":"32.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"35.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"47.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"58.4","Single Cell Type RNA - Paneth cells [nTPM]":"134.8","Single Cell Type RNA - Peritubular cells [nTPM]":"62.8","Single Cell Type RNA - Plasma cells [nTPM]":"37.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"60.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"376.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"321.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"73.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"80.0","Single Cell Type RNA - Sertoli cells [nTPM]":"72.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"72.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"80.7","Single Cell Type RNA - Spermatocytes [nTPM]":"120.4","Single Cell Type RNA - Spermatogonia [nTPM]":"49.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"53.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"54.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"186.6","Single Cell Type RNA - T-cells [nTPM]":"45.2","Single Cell Type RNA - Theca cells [nTPM]":"194.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"113.5","Single Cell Type RNA - Urothelial cells [nTPM]":"110.3"},{"Gene":"HAL","Gene synonym":["HIS"],"Ensembl":"ENSG00000084110","Gene description":"Histidine ammonia-lyase","Uniprot":["P42357"],"Chromosome":"12","Position":"95972662-95996365","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Histidine metabolism"],"Molecular function":["Lyase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"liver":"198.2","skin 1":"61.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Hepatocytes":"129.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"liver cancer":"23.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"56.9","neutrophil":"73.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"73.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"2.2","NB-4":"2.8","THP-1":"11.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038547","HPA038548"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"280000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA038547":"AB_10669541","HPA038548":"AB_10673175"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.4","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"2.9","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"11.5","Tissue RNA - breast [nTPM]":"2.2","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"0.8","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.5","Tissue RNA - duodenum [nTPM]":"0.6","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"1.0","Tissue RNA - fallopian tube [nTPM]":"0.7","Tissue RNA - gallbladder [nTPM]":"0.6","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"198.2","Tissue RNA - lung [nTPM]":"2.3","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.9","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"3.0","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.6","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"61.1","Tissue RNA - small intestine [nTPM]":"0.8","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"7.6","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"1.4","Tissue RNA - urinary bladder [nTPM]":"0.5","Tissue RNA - vagina [nTPM]":"1.4","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"2.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.6","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.3","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"2.8","Cell RNA - NTERA-2 [nTPM]":"0.9","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.6","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"11.4","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.5","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"1.7","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"56.9","Blood RNA - classical monocyte [nTPM]":"15.1","Blood RNA - eosinophil [nTPM]":"2.4","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"5.7","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"3.4","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"73.3","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"13.6","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"4.4","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"0.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"9.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"129.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"7.7","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"3.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"6.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"1.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"HAMP","Gene synonym":["HEPC","HFE2B","LEAP-1","LEAP1"],"Ensembl":"ENSG00000105697","Gene description":"Hepcidin antimicrobial peptide","Uniprot":["P81172"],"Chromosome":"19","Position":"35280716-35285143","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted secreted proteins","Transporters"],"Biological process":null,"Molecular function":["Antibiotic","Antimicrobial","Fungicide","Hormone"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"liver":"2054.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"17","RNA single cell type specific nTPM":{"Hepatocytes":"3227.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"glioma":"6.5","liver cancer":"16.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"myeloid DC":"1.5","plasmacytoid DC":"4.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"dendritic cells":"4.6"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"440","RNA cell line specific nTPM":{"Hep G2":"448.0"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":1900000,"Blood concentration - Conc. blood MS [pg\/L]":"10000000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.77e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.0","Tissue RNA - adrenal gland [nTPM]":"1.2","Tissue RNA - amygdala [nTPM]":"17.7","Tissue RNA - appendix [nTPM]":"2.0","Tissue RNA - basal ganglia [nTPM]":"17.6","Tissue RNA - bone marrow [nTPM]":"5.4","Tissue RNA - breast [nTPM]":"1.5","Tissue RNA - cerebellum [nTPM]":"17.4","Tissue RNA - cerebral cortex [nTPM]":"30.4","Tissue RNA - cervix [nTPM]":"2.3","Tissue RNA - choroid plexus [nTPM]":"20.8","Tissue RNA - colon [nTPM]":"0.8","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"0.5","Tissue RNA - fallopian tube [nTPM]":"2.8","Tissue RNA - gallbladder [nTPM]":"0.6","Tissue RNA - heart muscle [nTPM]":"415.0","Tissue RNA - hippocampal formation [nTPM]":"17.8","Tissue RNA - hypothalamus [nTPM]":"20.2","Tissue RNA - kidney [nTPM]":"1.1","Tissue RNA - liver [nTPM]":"2054.8","Tissue RNA - lung [nTPM]":"3.2","Tissue RNA - lymph node [nTPM]":"4.0","Tissue RNA - medulla oblongata [nTPM]":"48.0","Tissue RNA - midbrain [nTPM]":"24.9","Tissue RNA - ovary [nTPM]":"3.2","Tissue RNA - pancreas [nTPM]":"88.0","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"5.8","Tissue RNA - placenta [nTPM]":"2.3","Tissue RNA - pons [nTPM]":"25.8","Tissue RNA - prostate [nTPM]":"2.7","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"4.2","Tissue RNA - salivary gland [nTPM]":"1.2","Tissue RNA - seminal vesicle [nTPM]":"1.3","Tissue RNA - skeletal muscle [nTPM]":"1.2","Tissue RNA - skin 1 [nTPM]":"1.1","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"1.0","Tissue RNA - spinal cord [nTPM]":"21.5","Tissue RNA - spleen [nTPM]":"1.1","Tissue RNA - stomach 1 [nTPM]":"1.1","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"18.7","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"4.4","Tissue RNA - urinary bladder [nTPM]":"1.6","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"21.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.7","Cell RNA - Hep G2 [nTPM]":"448.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.6","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.5","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.7","Cell RNA - SCLC-21H [nTPM]":"1.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.6","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"4.6","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"17.7","Brain RNA - basal ganglia [nTPM]":"17.6","Brain RNA - cerebellum [nTPM]":"17.4","Brain RNA - cerebral cortex [nTPM]":"30.4","Brain RNA - hippocampal formation [nTPM]":"17.8","Brain RNA - hypothalamus [nTPM]":"20.2","Brain RNA - medulla oblongata [nTPM]":"48.0","Brain RNA - midbrain [nTPM]":"24.9","Brain RNA - pons [nTPM]":"25.8","Brain RNA - spinal cord [nTPM]":"21.5","Brain RNA - thalamus [nTPM]":"18.7","Brain RNA - white matter [nTPM]":"21.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"5.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.9","Single Cell Type RNA - dendritic cells [nTPM]":"0.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.0","Single Cell Type RNA - Endothelial cells [nTPM]":"13.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"89.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"99.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.2","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.8","Single Cell Type RNA - granulocytes [nTPM]":"75.7","Single Cell Type RNA - Granulosa cells [nTPM]":"0.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"45.3","Single Cell Type RNA - Hepatocytes [nTPM]":"3227.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"187.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"63.2","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"28.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"4.3","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"2.2"},{"Gene":"HARS1","Gene synonym":["HARS","HisRS","USH3B"],"Ensembl":"ENSG00000170445","Gene description":"Histidyl-tRNA synthetase 1","Uniprot":["P12081"],"Chromosome":"5","Position":"140673035-140691537","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Charcot-Marie-Tooth disease","Deafness","Disease variant","Neurodegeneration","Neuropathy","Retinitis pigmentosa","Usher syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"41.4","dendritic cells":"11.5","Extravillous trophoblasts":"48.6","Hofbauer cells":"35.7","Syncytiotrophoblasts":"36.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036539"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"190000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA036539":"AB_10669796"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.96e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Tissue RNA - adipose tissue [nTPM]":"31.6","Tissue RNA - adrenal gland [nTPM]":"39.9","Tissue RNA - amygdala [nTPM]":"64.8","Tissue RNA - appendix [nTPM]":"27.1","Tissue RNA - basal ganglia [nTPM]":"67.0","Tissue RNA - bone marrow [nTPM]":"24.3","Tissue RNA - breast [nTPM]":"29.3","Tissue RNA - cerebellum [nTPM]":"64.9","Tissue RNA - cerebral cortex [nTPM]":"88.7","Tissue RNA - cervix [nTPM]":"32.9","Tissue RNA - choroid plexus [nTPM]":"57.9","Tissue RNA - colon [nTPM]":"39.2","Tissue RNA - duodenum [nTPM]":"21.8","Tissue RNA - endometrium 1 [nTPM]":"34.5","Tissue RNA - epididymis [nTPM]":"27.1","Tissue RNA - esophagus [nTPM]":"42.9","Tissue RNA - fallopian tube [nTPM]":"30.8","Tissue RNA - gallbladder [nTPM]":"21.0","Tissue RNA - heart muscle [nTPM]":"38.3","Tissue RNA - hippocampal formation [nTPM]":"67.8","Tissue RNA - hypothalamus [nTPM]":"72.2","Tissue RNA - kidney [nTPM]":"30.7","Tissue RNA - liver [nTPM]":"47.3","Tissue RNA - lung [nTPM]":"27.2","Tissue RNA - lymph node [nTPM]":"29.6","Tissue RNA - medulla oblongata [nTPM]":"71.2","Tissue RNA - midbrain [nTPM]":"69.9","Tissue RNA - ovary [nTPM]":"31.3","Tissue RNA - pancreas [nTPM]":"40.8","Tissue RNA - parathyroid gland [nTPM]":"37.1","Tissue RNA - pituitary gland [nTPM]":"60.0","Tissue RNA - placenta [nTPM]":"18.5","Tissue RNA - pons [nTPM]":"72.8","Tissue RNA - prostate [nTPM]":"33.0","Tissue RNA - rectum [nTPM]":"29.6","Tissue RNA - retina [nTPM]":"18.5","Tissue RNA - salivary gland [nTPM]":"29.2","Tissue RNA - seminal vesicle [nTPM]":"32.0","Tissue RNA - skeletal muscle [nTPM]":"56.7","Tissue RNA - skin 1 [nTPM]":"53.9","Tissue RNA - small intestine [nTPM]":"28.6","Tissue RNA - smooth muscle [nTPM]":"35.2","Tissue RNA - spinal cord [nTPM]":"62.1","Tissue RNA - spleen [nTPM]":"32.2","Tissue RNA - stomach 1 [nTPM]":"36.0","Tissue RNA - testis [nTPM]":"25.6","Tissue RNA - thalamus [nTPM]":"77.4","Tissue RNA - thymus [nTPM]":"32.2","Tissue RNA - thyroid gland [nTPM]":"27.1","Tissue RNA - tongue [nTPM]":"33.4","Tissue RNA - tonsil [nTPM]":"36.8","Tissue RNA - urinary bladder [nTPM]":"34.3","Tissue RNA - vagina [nTPM]":"32.0","Tissue RNA - white matter [nTPM]":"71.9","Cell RNA - A-431 [nTPM]":"66.8","Cell RNA - A549 [nTPM]":"94.3","Cell RNA - AF22 [nTPM]":"55.5","Cell RNA - AN3-CA [nTPM]":"120.5","Cell RNA - ASC diff [nTPM]":"68.9","Cell RNA - ASC TERT1 [nTPM]":"74.9","Cell RNA - BEWO [nTPM]":"57.9","Cell RNA - BJ [nTPM]":"104.8","Cell RNA - BJ hTERT+ [nTPM]":"75.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"118.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"109.4","Cell RNA - CACO-2 [nTPM]":"174.8","Cell RNA - CAPAN-2 [nTPM]":"54.1","Cell RNA - Daudi [nTPM]":"88.4","Cell RNA - EFO-21 [nTPM]":"90.3","Cell RNA - fHDF\/TERT166 [nTPM]":"118.3","Cell RNA - GAMG [nTPM]":"94.3","Cell RNA - HaCaT [nTPM]":"66.6","Cell RNA - HAP1 [nTPM]":"85.9","Cell RNA - HBEC3-KT [nTPM]":"169.2","Cell RNA - HBF TERT88 [nTPM]":"111.6","Cell RNA - HDLM-2 [nTPM]":"74.5","Cell RNA - HEK 293 [nTPM]":"105.0","Cell RNA - HEL [nTPM]":"63.7","Cell RNA - HeLa [nTPM]":"115.4","Cell RNA - Hep G2 [nTPM]":"111.8","Cell RNA - HHSteC [nTPM]":"86.3","Cell RNA - HL-60 [nTPM]":"101.1","Cell RNA - HMC-1 [nTPM]":"49.8","Cell RNA - HSkMC [nTPM]":"80.4","Cell RNA - hTCEpi [nTPM]":"51.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"129.0","Cell RNA - hTERT-HME1 [nTPM]":"72.6","Cell RNA - hTERT-RPE1 [nTPM]":"69.5","Cell RNA - HUVEC TERT2 [nTPM]":"122.1","Cell RNA - JURKAT [nTPM]":"52.2","Cell RNA - K-562 [nTPM]":"56.5","Cell RNA - Karpas-707 [nTPM]":"68.6","Cell RNA - LHCN-M2 [nTPM]":"125.6","Cell RNA - MCF7 [nTPM]":"111.0","Cell RNA - MOLT-4 [nTPM]":"71.8","Cell RNA - NB-4 [nTPM]":"100.6","Cell RNA - NTERA-2 [nTPM]":"43.3","Cell RNA - OE19 [nTPM]":"52.3","Cell RNA - PC-3 [nTPM]":"60.9","Cell RNA - REH [nTPM]":"65.4","Cell RNA - RH-30 [nTPM]":"82.0","Cell RNA - RPMI-8226 [nTPM]":"70.9","Cell RNA - RPTEC TERT1 [nTPM]":"97.0","Cell RNA - RT4 [nTPM]":"82.2","Cell RNA - SCLC-21H [nTPM]":"86.5","Cell RNA - SH-SY5Y [nTPM]":"83.7","Cell RNA - SiHa [nTPM]":"86.1","Cell RNA - SK-BR-3 [nTPM]":"121.5","Cell RNA - SK-MEL-30 [nTPM]":"84.2","Cell RNA - SuSa [nTPM]":"54.9","Cell RNA - T-47d [nTPM]":"89.5","Cell RNA - THP-1 [nTPM]":"55.5","Cell RNA - TIME [nTPM]":"100.3","Cell RNA - U-138 MG [nTPM]":"107.8","Cell RNA - U-2 OS [nTPM]":"41.6","Cell RNA - U-2197 [nTPM]":"61.5","Cell RNA - U-251 MG [nTPM]":"144.7","Cell RNA - U-266\/70 [nTPM]":"68.5","Cell RNA - U-266\/84 [nTPM]":"90.5","Cell RNA - U-698 [nTPM]":"89.4","Cell RNA - U-87 MG [nTPM]":"82.8","Cell RNA - U-937 [nTPM]":"83.1","Cell RNA - WM-115 [nTPM]":"76.1","Blood RNA - basophil [nTPM]":"16.2","Blood RNA - classical monocyte [nTPM]":"31.2","Blood RNA - eosinophil [nTPM]":"24.0","Blood RNA - gdT-cell [nTPM]":"61.0","Blood RNA - intermediate monocyte [nTPM]":"46.3","Blood RNA - MAIT T-cell [nTPM]":"54.2","Blood RNA - memory B-cell [nTPM]":"34.9","Blood RNA - memory CD4 T-cell [nTPM]":"54.1","Blood RNA - memory CD8 T-cell [nTPM]":"57.6","Blood RNA - myeloid DC [nTPM]":"48.5","Blood RNA - naive B-cell [nTPM]":"34.6","Blood RNA - naive CD4 T-cell [nTPM]":"58.1","Blood RNA - naive CD8 T-cell [nTPM]":"55.4","Blood RNA - neutrophil [nTPM]":"8.1","Blood RNA - NK-cell [nTPM]":"59.3","Blood RNA - non-classical monocyte [nTPM]":"54.9","Blood RNA - plasmacytoid DC [nTPM]":"34.3","Blood RNA - T-reg [nTPM]":"51.3","Blood RNA - total PBMC [nTPM]":"56.7","Brain RNA - amygdala [nTPM]":"64.8","Brain RNA - basal ganglia [nTPM]":"67.0","Brain RNA - cerebellum [nTPM]":"64.9","Brain RNA - cerebral cortex [nTPM]":"88.7","Brain RNA - hippocampal formation [nTPM]":"67.8","Brain RNA - hypothalamus [nTPM]":"72.2","Brain RNA - medulla oblongata [nTPM]":"71.2","Brain RNA - midbrain [nTPM]":"69.9","Brain RNA - pons [nTPM]":"72.8","Brain RNA - spinal cord [nTPM]":"62.1","Brain RNA - thalamus [nTPM]":"77.4","Brain RNA - white matter [nTPM]":"71.9","Single Cell Type RNA - Adipocytes [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"41.4","Single Cell Type RNA - dendritic cells [nTPM]":"11.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"3.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"48.6","Single Cell Type RNA - Fibroblasts [nTPM]":"6.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"35.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"4.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"36.0","Single Cell Type RNA - T-cells [nTPM]":"1.7","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"HARS2","Gene synonym":["HARSL","HARSR","HO3"],"Ensembl":"ENSG00000112855","Gene description":"Histidyl-tRNA synthetase 2, mitochondrial","Uniprot":["P49590"],"Chromosome":"5","Position":"140691430-140699305","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Deafness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035941","HPA075303"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA035941":"AB_10671237","HPA075303":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.49e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.19e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.92e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Tissue RNA - adipose tissue [nTPM]":"19.6","Tissue RNA - adrenal gland [nTPM]":"24.6","Tissue RNA - amygdala [nTPM]":"14.0","Tissue RNA - appendix [nTPM]":"13.8","Tissue RNA - basal ganglia [nTPM]":"14.2","Tissue RNA - bone marrow [nTPM]":"14.4","Tissue RNA - breast [nTPM]":"18.9","Tissue RNA - cerebellum [nTPM]":"13.7","Tissue RNA - cerebral cortex [nTPM]":"14.2","Tissue RNA - cervix [nTPM]":"22.0","Tissue RNA - choroid plexus [nTPM]":"16.8","Tissue RNA - colon [nTPM]":"23.5","Tissue RNA - duodenum [nTPM]":"16.6","Tissue RNA - endometrium 1 [nTPM]":"19.5","Tissue RNA - epididymis [nTPM]":"15.0","Tissue RNA - esophagus [nTPM]":"20.0","Tissue RNA - fallopian tube [nTPM]":"18.4","Tissue RNA - gallbladder [nTPM]":"9.8","Tissue RNA - heart muscle [nTPM]":"27.9","Tissue RNA - hippocampal formation [nTPM]":"14.0","Tissue RNA - hypothalamus [nTPM]":"14.2","Tissue RNA - kidney [nTPM]":"23.3","Tissue RNA - liver [nTPM]":"19.3","Tissue RNA - lung [nTPM]":"16.0","Tissue RNA - lymph node [nTPM]":"15.1","Tissue RNA - medulla oblongata [nTPM]":"14.1","Tissue RNA - midbrain [nTPM]":"14.0","Tissue RNA - ovary [nTPM]":"21.1","Tissue RNA - pancreas [nTPM]":"15.6","Tissue RNA - parathyroid gland [nTPM]":"20.8","Tissue RNA - pituitary gland [nTPM]":"20.8","Tissue RNA - placenta [nTPM]":"14.2","Tissue RNA - pons [nTPM]":"14.4","Tissue RNA - prostate [nTPM]":"20.2","Tissue RNA - rectum [nTPM]":"22.3","Tissue RNA - retina [nTPM]":"11.5","Tissue RNA - salivary gland [nTPM]":"17.5","Tissue RNA - seminal vesicle [nTPM]":"13.4","Tissue RNA - skeletal muscle [nTPM]":"35.0","Tissue RNA - skin 1 [nTPM]":"21.1","Tissue RNA - small intestine [nTPM]":"20.9","Tissue RNA - smooth muscle [nTPM]":"14.0","Tissue RNA - spinal cord [nTPM]":"13.8","Tissue RNA - spleen [nTPM]":"26.9","Tissue RNA - stomach 1 [nTPM]":"20.4","Tissue RNA - testis [nTPM]":"14.8","Tissue RNA - thalamus [nTPM]":"14.3","Tissue RNA - thymus [nTPM]":"15.2","Tissue RNA - thyroid gland [nTPM]":"19.0","Tissue RNA - tongue [nTPM]":"28.4","Tissue RNA - tonsil [nTPM]":"16.1","Tissue RNA - urinary bladder [nTPM]":"21.1","Tissue RNA - vagina [nTPM]":"20.6","Tissue RNA - white matter [nTPM]":"15.7","Cell RNA - A-431 [nTPM]":"20.9","Cell RNA - A549 [nTPM]":"46.2","Cell RNA - AF22 [nTPM]":"19.6","Cell RNA - AN3-CA [nTPM]":"50.6","Cell RNA - ASC diff [nTPM]":"21.9","Cell RNA - ASC TERT1 [nTPM]":"28.6","Cell RNA - BEWO [nTPM]":"32.3","Cell RNA - BJ [nTPM]":"26.3","Cell RNA - BJ hTERT+ [nTPM]":"29.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"36.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"31.4","Cell RNA - CACO-2 [nTPM]":"42.7","Cell RNA - CAPAN-2 [nTPM]":"25.5","Cell RNA - Daudi [nTPM]":"26.3","Cell RNA - EFO-21 [nTPM]":"41.3","Cell RNA - fHDF\/TERT166 [nTPM]":"29.3","Cell RNA - GAMG [nTPM]":"35.5","Cell RNA - HaCaT [nTPM]":"25.9","Cell RNA - HAP1 [nTPM]":"27.3","Cell RNA - HBEC3-KT [nTPM]":"49.4","Cell RNA - HBF TERT88 [nTPM]":"33.2","Cell RNA - HDLM-2 [nTPM]":"26.6","Cell RNA - HEK 293 [nTPM]":"22.4","Cell RNA - HEL [nTPM]":"19.1","Cell RNA - HeLa [nTPM]":"45.3","Cell RNA - Hep G2 [nTPM]":"28.6","Cell RNA - HHSteC [nTPM]":"20.9","Cell RNA - HL-60 [nTPM]":"26.1","Cell RNA - HMC-1 [nTPM]":"27.1","Cell RNA - HSkMC [nTPM]":"27.0","Cell RNA - hTCEpi [nTPM]":"32.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"35.3","Cell RNA - hTERT-HME1 [nTPM]":"39.7","Cell RNA - hTERT-RPE1 [nTPM]":"29.4","Cell RNA - HUVEC TERT2 [nTPM]":"26.5","Cell RNA - JURKAT [nTPM]":"27.4","Cell RNA - K-562 [nTPM]":"18.0","Cell RNA - Karpas-707 [nTPM]":"24.1","Cell RNA - LHCN-M2 [nTPM]":"35.6","Cell RNA - MCF7 [nTPM]":"26.6","Cell RNA - MOLT-4 [nTPM]":"25.7","Cell RNA - NB-4 [nTPM]":"32.1","Cell RNA - NTERA-2 [nTPM]":"22.6","Cell RNA - OE19 [nTPM]":"15.7","Cell RNA - PC-3 [nTPM]":"28.9","Cell RNA - REH [nTPM]":"25.8","Cell RNA - RH-30 [nTPM]":"19.9","Cell RNA - RPMI-8226 [nTPM]":"26.8","Cell RNA - RPTEC TERT1 [nTPM]":"33.9","Cell RNA - RT4 [nTPM]":"48.1","Cell RNA - SCLC-21H [nTPM]":"27.0","Cell RNA - SH-SY5Y [nTPM]":"38.9","Cell RNA - SiHa [nTPM]":"38.1","Cell RNA - SK-BR-3 [nTPM]":"61.0","Cell RNA - SK-MEL-30 [nTPM]":"54.2","Cell RNA - SuSa [nTPM]":"28.5","Cell RNA - T-47d [nTPM]":"54.0","Cell RNA - THP-1 [nTPM]":"25.5","Cell RNA - TIME [nTPM]":"32.5","Cell RNA - U-138 MG [nTPM]":"32.4","Cell RNA - U-2 OS [nTPM]":"17.8","Cell RNA - U-2197 [nTPM]":"18.2","Cell RNA - U-251 MG [nTPM]":"35.2","Cell RNA - U-266\/70 [nTPM]":"23.6","Cell RNA - U-266\/84 [nTPM]":"37.0","Cell RNA - U-698 [nTPM]":"25.2","Cell RNA - U-87 MG [nTPM]":"25.4","Cell RNA - U-937 [nTPM]":"29.5","Cell RNA - WM-115 [nTPM]":"32.9","Blood RNA - basophil [nTPM]":"37.7","Blood RNA - classical monocyte [nTPM]":"13.1","Blood RNA - eosinophil [nTPM]":"28.6","Blood RNA - gdT-cell [nTPM]":"19.1","Blood RNA - intermediate monocyte [nTPM]":"18.9","Blood RNA - MAIT T-cell [nTPM]":"21.1","Blood RNA - memory B-cell [nTPM]":"16.9","Blood RNA - memory CD4 T-cell [nTPM]":"18.4","Blood RNA - memory CD8 T-cell [nTPM]":"19.2","Blood RNA - myeloid DC [nTPM]":"14.9","Blood RNA - naive B-cell [nTPM]":"14.8","Blood RNA - naive CD4 T-cell [nTPM]":"19.0","Blood RNA - naive CD8 T-cell [nTPM]":"20.6","Blood RNA - neutrophil [nTPM]":"15.1","Blood RNA - NK-cell [nTPM]":"29.3","Blood RNA - non-classical monocyte [nTPM]":"15.0","Blood RNA - plasmacytoid DC [nTPM]":"12.1","Blood RNA - T-reg [nTPM]":"20.1","Blood RNA - total PBMC [nTPM]":"13.3","Brain RNA - amygdala [nTPM]":"14.0","Brain RNA - basal ganglia [nTPM]":"14.2","Brain RNA - cerebellum [nTPM]":"13.7","Brain RNA - cerebral cortex [nTPM]":"14.2","Brain RNA - hippocampal formation [nTPM]":"14.0","Brain RNA - hypothalamus [nTPM]":"14.2","Brain RNA - medulla oblongata [nTPM]":"14.1","Brain RNA - midbrain [nTPM]":"14.0","Brain RNA - pons [nTPM]":"14.4","Brain RNA - spinal cord [nTPM]":"13.8","Brain RNA - thalamus [nTPM]":"14.3","Brain RNA - white matter [nTPM]":"15.7","Single Cell Type RNA - Adipocytes [nTPM]":"8.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.8","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"12.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"5.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"20.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"7.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.3","Single Cell Type RNA - dendritic cells [nTPM]":"6.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"14.9","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.0","Single Cell Type RNA - Endothelial cells [nTPM]":"9.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.7","Single Cell Type RNA - Erythroid cells [nTPM]":"9.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.7","Single Cell Type RNA - Fibroblasts [nTPM]":"6.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.4","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"11.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.7","Single Cell Type RNA - Hepatocytes [nTPM]":"7.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.7","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"8.2","Single Cell Type RNA - Langerhans cells [nTPM]":"6.2","Single Cell Type RNA - Late spermatids [nTPM]":"2.3","Single Cell Type RNA - Leydig cells [nTPM]":"9.3","Single Cell Type RNA - Macrophages [nTPM]":"7.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"12.8","Single Cell Type RNA - Muller glia cells [nTPM]":"8.3","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.3","Single Cell Type RNA - Paneth cells [nTPM]":"12.1","Single Cell Type RNA - Peritubular cells [nTPM]":"10.5","Single Cell Type RNA - Plasma cells [nTPM]":"9.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.0","Single Cell Type RNA - Spermatocytes [nTPM]":"8.9","Single Cell Type RNA - Spermatogonia [nTPM]":"14.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.4","Single Cell Type RNA - T-cells [nTPM]":"8.0","Single Cell Type RNA - Theca cells [nTPM]":"11.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.7","Single Cell Type RNA - Urothelial cells [nTPM]":"4.4"},{"Gene":"HAS2","Gene synonym":[],"Ensembl":"ENSG00000170961","Gene description":"Hyaluronan synthase 2","Uniprot":["Q92819"],"Chromosome":"8","Position":"121612116-121641440","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"22.7","urinary bladder":"20.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"54.1","Fibroblasts":"62.1","Langerhans cells":"28.9","Melanocytes":"30.2","Smooth muscle cells":"30.7","Urothelial cells":"89.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"HBF TERT88":"157.8","hTEC\/SVTERT24-B":"153.8","LHCN-M2":"206.5","U-138 MG":"396.9","U-251 MG":"123.7"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052060"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA052060":"AB_2681712"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-3"},"Tissue RNA - adipose tissue [nTPM]":"22.7","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"0.6","Tissue RNA - appendix [nTPM]":"9.0","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"5.3","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"0.7","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"4.1","Tissue RNA - duodenum [nTPM]":"2.8","Tissue RNA - endometrium 1 [nTPM]":"0.8","Tissue RNA - epididymis [nTPM]":"1.2","Tissue RNA - esophagus [nTPM]":"1.6","Tissue RNA - fallopian tube [nTPM]":"1.7","Tissue RNA - gallbladder [nTPM]":"7.8","Tissue RNA - heart muscle [nTPM]":"4.0","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"1.5","Tissue RNA - kidney [nTPM]":"1.1","Tissue RNA - liver [nTPM]":"2.9","Tissue RNA - lung [nTPM]":"3.7","Tissue RNA - lymph node [nTPM]":"1.6","Tissue RNA - medulla oblongata [nTPM]":"1.6","Tissue RNA - midbrain [nTPM]":"2.1","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.9","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"2.3","Tissue RNA - pons [nTPM]":"1.3","Tissue RNA - prostate [nTPM]":"1.1","Tissue RNA - rectum [nTPM]":"5.6","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"1.0","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"2.3","Tissue RNA - small intestine [nTPM]":"5.2","Tissue RNA - smooth muscle [nTPM]":"3.9","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"2.0","Tissue RNA - testis [nTPM]":"1.8","Tissue RNA - thalamus [nTPM]":"1.3","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"0.9","Tissue RNA - urinary bladder [nTPM]":"20.5","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"0.9","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"2.8","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"4.7","Cell RNA - ASC TERT1 [nTPM]":"11.8","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"23.5","Cell RNA - BJ hTERT+ [nTPM]":"17.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"29.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"51.2","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"20.8","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"4.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"157.8","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.6","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"19.9","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"31.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"153.8","Cell RNA - hTERT-HME1 [nTPM]":"14.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"206.5","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"3.4","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"26.6","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"2.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.4","Cell RNA - SiHa [nTPM]":"10.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"5.6","Cell RNA - SuSa [nTPM]":"9.0","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"396.9","Cell RNA - U-2 OS [nTPM]":"1.4","Cell RNA - U-2197 [nTPM]":"37.7","Cell RNA - U-251 MG [nTPM]":"123.7","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"8.5","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"8.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.6","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"1.5","Brain RNA - medulla oblongata [nTPM]":"1.6","Brain RNA - midbrain [nTPM]":"2.1","Brain RNA - pons [nTPM]":"1.3","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"1.3","Brain RNA - white matter [nTPM]":"0.9","Single Cell Type RNA - Adipocytes [nTPM]":"2.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"54.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.9","Single Cell Type RNA - Early spermatids [nTPM]":"19.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.5","Single Cell Type RNA - Endothelial cells [nTPM]":"7.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"62.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"13.4","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"28.9","Single Cell Type RNA - Late spermatids [nTPM]":"3.4","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.6","Single Cell Type RNA - Paneth cells [nTPM]":"1.9","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"30.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"1.5","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.9","Single Cell Type RNA - Urothelial cells [nTPM]":"89.3"},{"Gene":"HCCS","Gene synonym":["CCHL","MLS"],"Ensembl":"ENSG00000004961","Gene description":"Holocytochrome c synthase","Uniprot":["P53701"],"Chromosome":"X","Position":"11111301-11123086","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Lyase"],"Disease involvement":["Disease variant","Microphthalmia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002946"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA002946":"AB_1079041"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.69e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.35e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.17e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Tissue RNA - adipose tissue [nTPM]":"13.9","Tissue RNA - adrenal gland [nTPM]":"16.1","Tissue RNA - amygdala [nTPM]":"6.2","Tissue RNA - appendix [nTPM]":"13.7","Tissue RNA - basal ganglia [nTPM]":"6.7","Tissue RNA - bone marrow [nTPM]":"20.5","Tissue RNA - breast [nTPM]":"12.6","Tissue RNA - cerebellum [nTPM]":"7.0","Tissue RNA - cerebral cortex [nTPM]":"8.4","Tissue RNA - cervix [nTPM]":"8.4","Tissue RNA - choroid plexus [nTPM]":"8.4","Tissue RNA - colon [nTPM]":"21.6","Tissue RNA - duodenum [nTPM]":"23.1","Tissue RNA - endometrium 1 [nTPM]":"9.6","Tissue RNA - epididymis [nTPM]":"7.6","Tissue RNA - esophagus [nTPM]":"19.3","Tissue RNA - fallopian tube [nTPM]":"8.5","Tissue RNA - gallbladder [nTPM]":"10.8","Tissue RNA - heart muscle [nTPM]":"39.0","Tissue RNA - hippocampal formation [nTPM]":"7.4","Tissue RNA - hypothalamus [nTPM]":"6.8","Tissue RNA - kidney [nTPM]":"17.6","Tissue RNA - liver [nTPM]":"22.9","Tissue RNA - lung [nTPM]":"11.5","Tissue RNA - lymph node [nTPM]":"15.6","Tissue RNA - medulla oblongata [nTPM]":"6.7","Tissue RNA - midbrain [nTPM]":"6.2","Tissue RNA - ovary [nTPM]":"8.3","Tissue RNA - pancreas [nTPM]":"9.9","Tissue RNA - parathyroid gland [nTPM]":"25.1","Tissue RNA - pituitary gland [nTPM]":"8.3","Tissue RNA - placenta [nTPM]":"13.1","Tissue RNA - pons [nTPM]":"6.4","Tissue RNA - prostate [nTPM]":"9.5","Tissue RNA - rectum [nTPM]":"21.6","Tissue RNA - retina [nTPM]":"13.5","Tissue RNA - salivary gland [nTPM]":"15.2","Tissue RNA - seminal vesicle [nTPM]":"10.0","Tissue RNA - skeletal muscle [nTPM]":"64.4","Tissue RNA - skin 1 [nTPM]":"17.6","Tissue RNA - small intestine [nTPM]":"20.2","Tissue RNA - smooth muscle [nTPM]":"12.5","Tissue RNA - spinal cord [nTPM]":"6.2","Tissue RNA - spleen [nTPM]":"14.5","Tissue RNA - stomach 1 [nTPM]":"15.3","Tissue RNA - testis [nTPM]":"10.2","Tissue RNA - thalamus [nTPM]":"6.7","Tissue RNA - thymus [nTPM]":"13.0","Tissue RNA - thyroid gland [nTPM]":"10.8","Tissue RNA - tongue [nTPM]":"57.0","Tissue RNA - tonsil [nTPM]":"17.1","Tissue RNA - urinary bladder [nTPM]":"22.3","Tissue RNA - vagina [nTPM]":"11.6","Tissue RNA - white matter [nTPM]":"6.1","Cell RNA - A-431 [nTPM]":"54.3","Cell RNA - A549 [nTPM]":"60.5","Cell RNA - AF22 [nTPM]":"31.8","Cell RNA - AN3-CA [nTPM]":"28.5","Cell RNA - ASC diff [nTPM]":"25.6","Cell RNA - ASC TERT1 [nTPM]":"25.2","Cell RNA - BEWO [nTPM]":"29.2","Cell RNA - BJ [nTPM]":"52.0","Cell RNA - BJ hTERT+ [nTPM]":"43.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"67.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"57.5","Cell RNA - CACO-2 [nTPM]":"70.7","Cell RNA - CAPAN-2 [nTPM]":"38.5","Cell RNA - Daudi [nTPM]":"34.3","Cell RNA - EFO-21 [nTPM]":"26.3","Cell RNA - fHDF\/TERT166 [nTPM]":"46.1","Cell RNA - GAMG [nTPM]":"80.8","Cell RNA - HaCaT [nTPM]":"49.8","Cell RNA - HAP1 [nTPM]":"63.2","Cell RNA - HBEC3-KT [nTPM]":"51.8","Cell RNA - HBF TERT88 [nTPM]":"70.5","Cell RNA - HDLM-2 [nTPM]":"30.8","Cell RNA - HEK 293 [nTPM]":"48.0","Cell RNA - HEL [nTPM]":"34.1","Cell RNA - HeLa [nTPM]":"80.8","Cell RNA - Hep G2 [nTPM]":"38.6","Cell RNA - HHSteC [nTPM]":"47.3","Cell RNA - HL-60 [nTPM]":"40.9","Cell RNA - HMC-1 [nTPM]":"39.4","Cell RNA - HSkMC [nTPM]":"24.2","Cell RNA - hTCEpi [nTPM]":"37.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"67.9","Cell RNA - hTERT-HME1 [nTPM]":"46.5","Cell RNA - hTERT-RPE1 [nTPM]":"37.9","Cell RNA - HUVEC TERT2 [nTPM]":"49.1","Cell RNA - JURKAT [nTPM]":"26.1","Cell RNA - K-562 [nTPM]":"63.1","Cell RNA - Karpas-707 [nTPM]":"41.1","Cell RNA - LHCN-M2 [nTPM]":"46.3","Cell RNA - MCF7 [nTPM]":"72.5","Cell RNA - MOLT-4 [nTPM]":"28.0","Cell RNA - NB-4 [nTPM]":"31.4","Cell RNA - NTERA-2 [nTPM]":"51.5","Cell RNA - OE19 [nTPM]":"36.6","Cell RNA - PC-3 [nTPM]":"70.1","Cell RNA - REH [nTPM]":"27.3","Cell RNA - RH-30 [nTPM]":"59.9","Cell RNA - RPMI-8226 [nTPM]":"65.4","Cell RNA - RPTEC TERT1 [nTPM]":"44.0","Cell RNA - RT4 [nTPM]":"44.8","Cell RNA - SCLC-21H [nTPM]":"20.9","Cell RNA - SH-SY5Y [nTPM]":"24.2","Cell RNA - SiHa [nTPM]":"54.8","Cell RNA - SK-BR-3 [nTPM]":"58.7","Cell RNA - SK-MEL-30 [nTPM]":"38.2","Cell RNA - SuSa [nTPM]":"66.7","Cell RNA - T-47d [nTPM]":"45.6","Cell RNA - THP-1 [nTPM]":"27.1","Cell RNA - TIME [nTPM]":"48.7","Cell RNA - U-138 MG [nTPM]":"42.4","Cell RNA - U-2 OS [nTPM]":"23.6","Cell RNA - U-2197 [nTPM]":"110.4","Cell RNA - U-251 MG [nTPM]":"47.0","Cell RNA - U-266\/70 [nTPM]":"26.9","Cell RNA - U-266\/84 [nTPM]":"29.0","Cell RNA - U-698 [nTPM]":"47.8","Cell RNA - U-87 MG [nTPM]":"35.5","Cell RNA - U-937 [nTPM]":"28.8","Cell RNA - WM-115 [nTPM]":"42.7","Blood RNA - basophil [nTPM]":"25.6","Blood RNA - classical monocyte [nTPM]":"47.8","Blood RNA - eosinophil [nTPM]":"30.1","Blood RNA - gdT-cell [nTPM]":"20.2","Blood RNA - intermediate monocyte [nTPM]":"66.4","Blood RNA - MAIT T-cell [nTPM]":"19.0","Blood RNA - memory B-cell [nTPM]":"39.0","Blood RNA - memory CD4 T-cell [nTPM]":"19.6","Blood RNA - memory CD8 T-cell [nTPM]":"18.2","Blood RNA - myeloid DC [nTPM]":"62.2","Blood RNA - naive B-cell [nTPM]":"34.7","Blood RNA - naive CD4 T-cell [nTPM]":"17.1","Blood RNA - naive CD8 T-cell [nTPM]":"22.1","Blood RNA - neutrophil [nTPM]":"13.1","Blood RNA - NK-cell [nTPM]":"19.1","Blood RNA - non-classical monocyte [nTPM]":"57.4","Blood RNA - plasmacytoid DC [nTPM]":"56.2","Blood RNA - T-reg [nTPM]":"23.5","Blood RNA - total PBMC [nTPM]":"19.0","Brain RNA - amygdala [nTPM]":"6.2","Brain RNA - basal ganglia [nTPM]":"6.7","Brain RNA - cerebellum [nTPM]":"7.0","Brain RNA - cerebral cortex [nTPM]":"8.4","Brain RNA - hippocampal formation [nTPM]":"7.4","Brain RNA - hypothalamus [nTPM]":"6.8","Brain RNA - medulla oblongata [nTPM]":"6.7","Brain RNA - midbrain [nTPM]":"6.2","Brain RNA - pons [nTPM]":"6.4","Brain RNA - spinal cord [nTPM]":"6.2","Brain RNA - thalamus [nTPM]":"6.7","Brain RNA - white matter [nTPM]":"6.1","Single Cell Type RNA - Adipocytes [nTPM]":"15.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"2.3","Single Cell Type RNA - B-cells [nTPM]":"20.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"54.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"53.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"57.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.8","Single Cell Type RNA - Bipolar cells [nTPM]":"5.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"49.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"33.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"32.9","Single Cell Type RNA - dendritic cells [nTPM]":"12.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"50.9","Single Cell Type RNA - Ductal cells [nTPM]":"34.9","Single Cell Type RNA - Early spermatids [nTPM]":"13.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.4","Single Cell Type RNA - Endothelial cells [nTPM]":"21.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.8","Single Cell Type RNA - Erythroid cells [nTPM]":"32.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"29.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"37.9","Single Cell Type RNA - Fibroblasts [nTPM]":"17.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.7","Single Cell Type RNA - granulocytes [nTPM]":"13.3","Single Cell Type RNA - Granulosa cells [nTPM]":"10.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.7","Single Cell Type RNA - Hepatocytes [nTPM]":"18.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"41.8","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.2","Single Cell Type RNA - Ionocytes [nTPM]":"67.1","Single Cell Type RNA - Kupffer cells [nTPM]":"21.0","Single Cell Type RNA - Langerhans cells [nTPM]":"44.1","Single Cell Type RNA - Late spermatids [nTPM]":"2.3","Single Cell Type RNA - Leydig cells [nTPM]":"13.4","Single Cell Type RNA - Macrophages [nTPM]":"23.5","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"27.9","Single Cell Type RNA - Muller glia cells [nTPM]":"13.0","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"68.4","Single Cell Type RNA - Paneth cells [nTPM]":"31.9","Single Cell Type RNA - Peritubular cells [nTPM]":"10.5","Single Cell Type RNA - Plasma cells [nTPM]":"18.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"63.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"46.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"36.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.1","Single Cell Type RNA - Spermatocytes [nTPM]":"24.4","Single Cell Type RNA - Spermatogonia [nTPM]":"28.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"46.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"40.9","Single Cell Type RNA - T-cells [nTPM]":"12.0","Single Cell Type RNA - Theca cells [nTPM]":"15.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"30.2","Single Cell Type RNA - Urothelial cells [nTPM]":"88.6"},{"Gene":"HCK","Gene synonym":["JTK9"],"Ensembl":"ENSG00000101336","Gene description":"HCK proto-oncogene, Src family tyrosine kinase","Uniprot":["P08631"],"Chromosome":"20","Position":"32052197-32101856","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Exocytosis","Host-virus interaction","Immunity","Inflammatory response","Innate immunity","Phagocytosis"],"Molecular function":["Kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"112.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"150.7","Kupffer cells":"155.5","Langerhans cells":"89.2","Macrophages":"170.1","Microglial cells":"52.5","monocytes":"222.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"16","RNA blood cell specific nTPM":{"classical monocyte":"575.0","eosinophil":"707.8","intermediate monocyte":"1059.1","myeloid DC":"336.3","neutrophil":"801.3","non-classical monocyte":"1251.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"16","RNA blood lineage specific nTPM":{"dendritic cells":"336.3","granulocytes":"801.3","monocytes":"1251.7"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"THP-1":"69.3","U-937":"199.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005195","HPA035534","HPA063768"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":["Plasma membrane","Cytosol"],"Antibody RRID":{"CAB005195":"AB_631619","HPA035534":null,"HPA063768":"AB_2685118"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.66e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Tissue RNA - adipose tissue [nTPM]":"24.8","Tissue RNA - adrenal gland [nTPM]":"9.2","Tissue RNA - amygdala [nTPM]":"4.7","Tissue RNA - appendix [nTPM]":"100.0","Tissue RNA - basal ganglia [nTPM]":"5.0","Tissue RNA - bone marrow [nTPM]":"55.2","Tissue RNA - breast [nTPM]":"6.0","Tissue RNA - cerebellum [nTPM]":"5.5","Tissue RNA - cerebral cortex [nTPM]":"6.0","Tissue RNA - cervix [nTPM]":"5.5","Tissue RNA - choroid plexus [nTPM]":"13.7","Tissue RNA - colon [nTPM]":"12.8","Tissue RNA - duodenum [nTPM]":"15.2","Tissue RNA - endometrium 1 [nTPM]":"3.1","Tissue RNA - epididymis [nTPM]":"2.6","Tissue RNA - esophagus [nTPM]":"6.7","Tissue RNA - fallopian tube [nTPM]":"7.6","Tissue RNA - gallbladder [nTPM]":"14.4","Tissue RNA - heart muscle [nTPM]":"4.8","Tissue RNA - hippocampal formation [nTPM]":"4.7","Tissue RNA - hypothalamus [nTPM]":"6.2","Tissue RNA - kidney [nTPM]":"4.7","Tissue RNA - liver [nTPM]":"14.1","Tissue RNA - lung [nTPM]":"46.0","Tissue RNA - lymph node [nTPM]":"38.6","Tissue RNA - medulla oblongata [nTPM]":"9.9","Tissue RNA - midbrain [nTPM]":"6.8","Tissue RNA - ovary [nTPM]":"2.5","Tissue RNA - pancreas [nTPM]":"4.5","Tissue RNA - parathyroid gland [nTPM]":"2.1","Tissue RNA - pituitary gland [nTPM]":"3.1","Tissue RNA - placenta [nTPM]":"20.9","Tissue RNA - pons [nTPM]":"8.3","Tissue RNA - prostate [nTPM]":"4.0","Tissue RNA - rectum [nTPM]":"13.6","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"5.1","Tissue RNA - seminal vesicle [nTPM]":"4.7","Tissue RNA - skeletal muscle [nTPM]":"1.6","Tissue RNA - skin 1 [nTPM]":"5.8","Tissue RNA - small intestine [nTPM]":"17.8","Tissue RNA - smooth muscle [nTPM]":"25.3","Tissue RNA - spinal cord [nTPM]":"8.1","Tissue RNA - spleen [nTPM]":"112.1","Tissue RNA - stomach 1 [nTPM]":"6.7","Tissue RNA - testis [nTPM]":"2.3","Tissue RNA - thalamus [nTPM]":"8.4","Tissue RNA - thymus [nTPM]":"14.5","Tissue RNA - thyroid gland [nTPM]":"2.8","Tissue RNA - tongue [nTPM]":"6.9","Tissue RNA - tonsil [nTPM]":"39.3","Tissue RNA - urinary bladder [nTPM]":"32.8","Tissue RNA - vagina [nTPM]":"4.1","Tissue RNA - white matter [nTPM]":"12.0","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"1.6","Cell RNA - EFO-21 [nTPM]":"0.9","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"1.3","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"4.3","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"15.6","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"4.9","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.5","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.7","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"69.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"1.9","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"10.3","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"199.6","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"6.4","Blood RNA - classical monocyte [nTPM]":"575.0","Blood RNA - eosinophil [nTPM]":"707.8","Blood RNA - gdT-cell [nTPM]":"1.1","Blood RNA - intermediate monocyte [nTPM]":"1059.1","Blood RNA - MAIT T-cell [nTPM]":"1.3","Blood RNA - memory B-cell [nTPM]":"48.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"336.3","Blood RNA - naive B-cell [nTPM]":"43.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"801.3","Blood RNA - NK-cell [nTPM]":"11.0","Blood RNA - non-classical monocyte [nTPM]":"1251.7","Blood RNA - plasmacytoid DC [nTPM]":"30.4","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"566.4","Brain RNA - amygdala [nTPM]":"4.7","Brain RNA - basal ganglia [nTPM]":"5.0","Brain RNA - cerebellum [nTPM]":"5.5","Brain RNA - cerebral cortex [nTPM]":"6.0","Brain RNA - hippocampal formation [nTPM]":"4.7","Brain RNA - hypothalamus [nTPM]":"6.2","Brain RNA - medulla oblongata [nTPM]":"9.9","Brain RNA - midbrain [nTPM]":"6.8","Brain RNA - pons [nTPM]":"8.3","Brain RNA - spinal cord [nTPM]":"8.1","Brain RNA - thalamus [nTPM]":"8.4","Brain RNA - white matter [nTPM]":"12.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"17.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"3.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.9","Single Cell Type RNA - dendritic cells [nTPM]":"12.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"2.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"3.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.9","Single Cell Type RNA - Fibroblasts [nTPM]":"1.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"2.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"150.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.5","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"155.5","Single Cell Type RNA - Langerhans cells [nTPM]":"89.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"170.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"52.5","Single Cell Type RNA - monocytes [nTPM]":"222.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.6","Single Cell Type RNA - T-cells [nTPM]":"3.0","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.9","Single Cell Type RNA - Urothelial cells [nTPM]":"3.7"},{"Gene":"HCN1","Gene synonym":["BCNG-1","BCNG1","HAC-2"],"Ensembl":"ENSG00000164588","Gene description":"Hyperpolarization activated cyclic nucleotide gated potassium channel 1","Uniprot":["O60741"],"Chromosome":"5","Position":"45254948-45696498","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Potassium channel","Sodium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"brain":"7.2","retina":"17.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"671.7","Inhibitory neurons":"766.5","Rod photoreceptor cells":"199.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"7.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"WM-115":"1.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019195"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA019195":"AB_2670094"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.24e-3"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.63e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.4","Tissue RNA - amygdala [nTPM]":"1.8","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"2.4","Tissue RNA - cerebral cortex [nTPM]":"7.2","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.9","Tissue RNA - hippocampal formation [nTPM]":"2.5","Tissue RNA - hypothalamus [nTPM]":"1.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"17.6","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"2.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.8","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"2.4","Brain RNA - cerebral cortex [nTPM]":"7.2","Brain RNA - hippocampal formation [nTPM]":"2.5","Brain RNA - hypothalamus [nTPM]":"1.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"2.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"24.5","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"29.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"133.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"0.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"671.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"766.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"51.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"14.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"21.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"199.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"1.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"HCN4","Gene synonym":[],"Ensembl":"ENSG00000138622","Gene description":"Hyperpolarization activated cyclic nucleotide gated potassium channel 4","Uniprot":["Q9Y3Q4"],"Chromosome":"15","Position":"73319859-73368958","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Potassium channel","Sodium channel","Voltage-gated channel"],"Disease involvement":["Brugada syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"16","RNA tissue specific nTPM":{"brain":"8.5","heart muscle":"8.4","testis":"7.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"29.4","Late spermatids":"49.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"testis cancer":"3.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"1.3","CACO-2":"1.7","HDLM-2":"1.1","NTERA-2":"4.9","SuSa":"1.2","U-2 OS":"2.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA073174"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA073174":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.4","Tissue RNA - amygdala [nTPM]":"3.6","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.7","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"2.2","Tissue RNA - cerebral cortex [nTPM]":"1.8","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"8.4","Tissue RNA - hippocampal formation [nTPM]":"1.0","Tissue RNA - hypothalamus [nTPM]":"2.8","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"5.0","Tissue RNA - midbrain [nTPM]":"4.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"4.6","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"2.5","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"7.2","Tissue RNA - thalamus [nTPM]":"8.5","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"1.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"1.7","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"1.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"4.9","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"2.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.6","Brain RNA - basal ganglia [nTPM]":"0.7","Brain RNA - cerebellum [nTPM]":"2.2","Brain RNA - cerebral cortex [nTPM]":"1.8","Brain RNA - hippocampal formation [nTPM]":"1.0","Brain RNA - hypothalamus [nTPM]":"2.8","Brain RNA - medulla oblongata [nTPM]":"5.0","Brain RNA - midbrain [nTPM]":"4.2","Brain RNA - pons [nTPM]":"4.6","Brain RNA - spinal cord [nTPM]":"2.5","Brain RNA - thalamus [nTPM]":"8.5","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.5","Single Cell Type RNA - Early spermatids [nTPM]":"29.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"49.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.6","Single Cell Type RNA - Spermatogonia [nTPM]":"2.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"HECW2","Gene synonym":["KIAA1301","NEDL2"],"Ensembl":"ENSG00000138411","Gene description":"HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2","Uniprot":["Q9P2P5"],"Chromosome":"2","Position":"196189099-196593684","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"331.5","Hepatic stellate cells":"99.2","Inhibitory neurons":"375.4","Oligodendrocyte precursor cells":"143.2","Oligodendrocytes":"460.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"4.7","non-classical monocyte":"3.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"4.7","monocytes":"3.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"30.1","hTEC\/SVTERT24-B":"16.3","HUVEC TERT2":"20.9","SCLC-21H":"31.6","TIME":"26.3","U-138 MG":"21.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034609"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA034609":"AB_10669993"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.00e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.18e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.1","Tissue RNA - adrenal gland [nTPM]":"1.5","Tissue RNA - amygdala [nTPM]":"2.4","Tissue RNA - appendix [nTPM]":"1.2","Tissue RNA - basal ganglia [nTPM]":"3.5","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"1.7","Tissue RNA - cerebellum [nTPM]":"4.4","Tissue RNA - cerebral cortex [nTPM]":"6.1","Tissue RNA - cervix [nTPM]":"2.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"0.8","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"3.1","Tissue RNA - fallopian tube [nTPM]":"3.5","Tissue RNA - gallbladder [nTPM]":"2.1","Tissue RNA - heart muscle [nTPM]":"8.1","Tissue RNA - hippocampal formation [nTPM]":"3.3","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"1.6","Tissue RNA - liver [nTPM]":"2.7","Tissue RNA - lung [nTPM]":"5.3","Tissue RNA - lymph node [nTPM]":"2.0","Tissue RNA - medulla oblongata [nTPM]":"1.1","Tissue RNA - midbrain [nTPM]":"0.8","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.6","Tissue RNA - parathyroid gland [nTPM]":"4.3","Tissue RNA - pituitary gland [nTPM]":"1.2","Tissue RNA - placenta [nTPM]":"7.4","Tissue RNA - pons [nTPM]":"2.1","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"2.7","Tissue RNA - salivary gland [nTPM]":"0.9","Tissue RNA - seminal vesicle [nTPM]":"0.5","Tissue RNA - skeletal muscle [nTPM]":"1.4","Tissue RNA - skin 1 [nTPM]":"0.8","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"1.3","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"6.0","Tissue RNA - stomach 1 [nTPM]":"0.9","Tissue RNA - testis [nTPM]":"3.5","Tissue RNA - thalamus [nTPM]":"1.7","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"3.8","Tissue RNA - tongue [nTPM]":"3.5","Tissue RNA - tonsil [nTPM]":"2.4","Tissue RNA - urinary bladder [nTPM]":"1.0","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"8.2","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"1.4","Cell RNA - AF22 [nTPM]":"2.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"1.4","Cell RNA - ASC TERT1 [nTPM]":"4.2","Cell RNA - BEWO [nTPM]":"1.6","Cell RNA - BJ [nTPM]":"2.7","Cell RNA - BJ hTERT+ [nTPM]":"7.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.6","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"1.4","Cell RNA - EFO-21 [nTPM]":"0.5","Cell RNA - fHDF\/TERT166 [nTPM]":"13.4","Cell RNA - GAMG [nTPM]":"3.3","Cell RNA - HaCaT [nTPM]":"3.2","Cell RNA - HAP1 [nTPM]":"0.9","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"4.5","Cell RNA - HDLM-2 [nTPM]":"30.1","Cell RNA - HEK 293 [nTPM]":"1.6","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"2.3","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"1.0","Cell RNA - hTCEpi [nTPM]":"1.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.3","Cell RNA - hTERT-HME1 [nTPM]":"5.7","Cell RNA - hTERT-RPE1 [nTPM]":"4.1","Cell RNA - HUVEC TERT2 [nTPM]":"20.9","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"6.7","Cell RNA - MCF7 [nTPM]":"1.8","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.7","Cell RNA - NTERA-2 [nTPM]":"2.5","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"1.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.5","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"31.6","Cell RNA - SH-SY5Y [nTPM]":"2.5","Cell RNA - SiHa [nTPM]":"2.0","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"26.3","Cell RNA - U-138 MG [nTPM]":"21.7","Cell RNA - U-2 OS [nTPM]":"1.4","Cell RNA - U-2197 [nTPM]":"4.6","Cell RNA - U-251 MG [nTPM]":"0.7","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"1.3","Cell RNA - U-87 MG [nTPM]":"5.4","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.8","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"4.7","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"3.7","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"2.4","Brain RNA - basal ganglia [nTPM]":"3.5","Brain RNA - cerebellum [nTPM]":"4.4","Brain RNA - cerebral cortex [nTPM]":"6.1","Brain RNA - hippocampal formation [nTPM]":"3.3","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"1.1","Brain RNA - midbrain [nTPM]":"0.8","Brain RNA - pons [nTPM]":"2.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"1.7","Brain RNA - white matter [nTPM]":"8.2","Single Cell Type RNA - Adipocytes [nTPM]":"61.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.1","Single Cell Type RNA - Astrocytes [nTPM]":"12.7","Single Cell Type RNA - B-cells [nTPM]":"3.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"9.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"11.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.6","Single Cell Type RNA - Endothelial cells [nTPM]":"34.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"331.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"4.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"4.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"99.2","Single Cell Type RNA - Hepatocytes [nTPM]":"1.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"375.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"7.2","Single Cell Type RNA - Langerhans cells [nTPM]":"3.0","Single Cell Type RNA - Late spermatids [nTPM]":"5.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"1.2","Single Cell Type RNA - Muller glia cells [nTPM]":"12.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"143.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"460.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"3.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"6.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"1.4","Single Cell Type RNA - Theca cells [nTPM]":"0.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"HEPACAM","Gene synonym":["FLJ25530","GLIALCAM"],"Ensembl":"ENSG00000165478","Gene description":"Hepatic and glial cell adhesion molecule","Uniprot":["Q14CZ8"],"Chromosome":"11","Position":"124919205-124936412","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion","Cell cycle","Growth arrest","Growth regulation"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"222.6","choroid plexus":"79.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Astrocytes":"184.8","Oligodendrocyte precursor cells":"72.9","Oligodendrocytes":"163.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"glioma":"29.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"30","RNA cell line specific nTPM":{"Hep G2":"25.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017613","CAB025486"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB025486":null,"HPA017613":"AB_1850595"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"15.6","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"172.8","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"203.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"2.5","Tissue RNA - cerebellum [nTPM]":"170.4","Tissue RNA - cerebral cortex [nTPM]":"162.1","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"79.7","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"163.2","Tissue RNA - hypothalamus [nTPM]":"156.1","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"16.2","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"222.6","Tissue RNA - midbrain [nTPM]":"182.8","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"183.6","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"1.8","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.5","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"205.7","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"182.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"0.6","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"212.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"25.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.5","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"172.8","Brain RNA - basal ganglia [nTPM]":"203.3","Brain RNA - cerebellum [nTPM]":"170.4","Brain RNA - cerebral cortex [nTPM]":"162.1","Brain RNA - hippocampal formation [nTPM]":"163.2","Brain RNA - hypothalamus [nTPM]":"156.1","Brain RNA - medulla oblongata [nTPM]":"222.6","Brain RNA - midbrain [nTPM]":"182.8","Brain RNA - pons [nTPM]":"183.6","Brain RNA - spinal cord [nTPM]":"205.7","Brain RNA - thalamus [nTPM]":"182.0","Brain RNA - white matter [nTPM]":"212.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"184.8","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"11.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"15.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"72.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"163.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"HEPHL1","Gene synonym":["DKFZp686F22190"],"Ensembl":"ENSG00000181333","Gene description":"Hephaestin like 1","Uniprot":["Q6MZM0"],"Chromosome":"11","Position":"94021354-94114208","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Copper transport","Ion transport","Transport"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"esophagus":"4.5","lymphoid tissue":"9.5","skin 1":"3.8","vagina":"4.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Basal keratinocytes":"10.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"head and neck cancer":"20.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"HaCaT":"1.4","HBEC3-KT":"2.6"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"12","RNA mouse brain regional specific nTPM":{"olfactory bulb":"1.2"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031517"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"260000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 28: Keratinocytes - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031517":"AB_10603769"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.94e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.8","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"4.5","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"3.8","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"9.5","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"4.5","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"1.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"2.6","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"HERC1","Gene synonym":["p532","p619"],"Ensembl":"ENSG00000103657","Gene description":"HECT and RLD domain containing E3 ubiquitin protein ligase family member 1","Uniprot":["Q15751"],"Chromosome":"15","Position":"63608618-63833948","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transport","Ubl conjugation pathway"],"Molecular function":["Guanine-nucleotide releasing factor","Transferase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"458.8","Inhibitory neurons":"338.0","Oligodendrocytes":"201.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049749"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049749":"AB_2680866"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.87e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.66e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.36e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.04e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.5","Tissue RNA - adrenal gland [nTPM]":"7.4","Tissue RNA - amygdala [nTPM]":"8.6","Tissue RNA - appendix [nTPM]":"10.3","Tissue RNA - basal ganglia [nTPM]":"10.1","Tissue RNA - bone marrow [nTPM]":"27.4","Tissue RNA - breast [nTPM]":"12.7","Tissue RNA - cerebellum [nTPM]":"14.1","Tissue RNA - cerebral cortex [nTPM]":"20.3","Tissue RNA - cervix [nTPM]":"13.0","Tissue RNA - choroid plexus [nTPM]":"5.2","Tissue RNA - colon [nTPM]":"11.8","Tissue RNA - duodenum [nTPM]":"5.3","Tissue RNA - endometrium 1 [nTPM]":"10.8","Tissue RNA - epididymis [nTPM]":"6.5","Tissue RNA - esophagus [nTPM]":"8.1","Tissue RNA - fallopian tube [nTPM]":"7.6","Tissue RNA - gallbladder [nTPM]":"9.6","Tissue RNA - heart muscle [nTPM]":"15.2","Tissue RNA - hippocampal formation [nTPM]":"9.3","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"9.1","Tissue RNA - liver [nTPM]":"9.1","Tissue RNA - lung [nTPM]":"10.6","Tissue RNA - lymph node [nTPM]":"13.7","Tissue RNA - medulla oblongata [nTPM]":"1.7","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"18.5","Tissue RNA - pancreas [nTPM]":"8.4","Tissue RNA - parathyroid gland [nTPM]":"22.7","Tissue RNA - pituitary gland [nTPM]":"8.8","Tissue RNA - placenta [nTPM]":"10.3","Tissue RNA - pons [nTPM]":"1.8","Tissue RNA - prostate [nTPM]":"8.6","Tissue RNA - rectum [nTPM]":"9.2","Tissue RNA - retina [nTPM]":"18.3","Tissue RNA - salivary gland [nTPM]":"8.8","Tissue RNA - seminal vesicle [nTPM]":"10.3","Tissue RNA - skeletal muscle [nTPM]":"30.4","Tissue RNA - skin 1 [nTPM]":"12.1","Tissue RNA - small intestine [nTPM]":"9.9","Tissue RNA - smooth muscle [nTPM]":"12.4","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"15.2","Tissue RNA - stomach 1 [nTPM]":"10.2","Tissue RNA - testis [nTPM]":"11.5","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"25.6","Tissue RNA - thyroid gland [nTPM]":"14.0","Tissue RNA - tongue [nTPM]":"29.3","Tissue RNA - tonsil [nTPM]":"12.8","Tissue RNA - urinary bladder [nTPM]":"9.2","Tissue RNA - vagina [nTPM]":"7.9","Tissue RNA - white matter [nTPM]":"22.7","Cell RNA - A-431 [nTPM]":"13.5","Cell RNA - A549 [nTPM]":"17.1","Cell RNA - AF22 [nTPM]":"19.1","Cell RNA - AN3-CA [nTPM]":"6.6","Cell RNA - ASC diff [nTPM]":"33.3","Cell RNA - ASC TERT1 [nTPM]":"21.1","Cell RNA - BEWO [nTPM]":"6.4","Cell RNA - BJ [nTPM]":"10.3","Cell RNA - BJ hTERT+ [nTPM]":"13.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.3","Cell RNA - CACO-2 [nTPM]":"10.9","Cell RNA - CAPAN-2 [nTPM]":"5.3","Cell RNA - Daudi [nTPM]":"19.8","Cell RNA - EFO-21 [nTPM]":"9.3","Cell RNA - fHDF\/TERT166 [nTPM]":"19.8","Cell RNA - GAMG [nTPM]":"9.7","Cell RNA - HaCaT [nTPM]":"14.5","Cell RNA - HAP1 [nTPM]":"31.2","Cell RNA - HBEC3-KT [nTPM]":"9.0","Cell RNA - HBF TERT88 [nTPM]":"14.6","Cell RNA - HDLM-2 [nTPM]":"15.4","Cell RNA - HEK 293 [nTPM]":"9.6","Cell RNA - HEL [nTPM]":"42.5","Cell RNA - HeLa [nTPM]":"26.4","Cell RNA - Hep G2 [nTPM]":"7.8","Cell RNA - HHSteC [nTPM]":"5.3","Cell RNA - HL-60 [nTPM]":"31.6","Cell RNA - HMC-1 [nTPM]":"25.1","Cell RNA - HSkMC [nTPM]":"15.3","Cell RNA - hTCEpi [nTPM]":"8.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.1","Cell RNA - hTERT-HME1 [nTPM]":"14.5","Cell RNA - hTERT-RPE1 [nTPM]":"9.3","Cell RNA - HUVEC TERT2 [nTPM]":"22.7","Cell RNA - JURKAT [nTPM]":"13.3","Cell RNA - K-562 [nTPM]":"44.0","Cell RNA - Karpas-707 [nTPM]":"8.6","Cell RNA - LHCN-M2 [nTPM]":"9.4","Cell RNA - MCF7 [nTPM]":"21.7","Cell RNA - MOLT-4 [nTPM]":"11.3","Cell RNA - NB-4 [nTPM]":"6.5","Cell RNA - NTERA-2 [nTPM]":"9.3","Cell RNA - OE19 [nTPM]":"10.4","Cell RNA - PC-3 [nTPM]":"8.7","Cell RNA - REH [nTPM]":"12.2","Cell RNA - RH-30 [nTPM]":"20.6","Cell RNA - RPMI-8226 [nTPM]":"11.6","Cell RNA - RPTEC TERT1 [nTPM]":"4.4","Cell RNA - RT4 [nTPM]":"32.9","Cell RNA - SCLC-21H [nTPM]":"17.0","Cell RNA - SH-SY5Y [nTPM]":"8.4","Cell RNA - SiHa [nTPM]":"18.2","Cell RNA - SK-BR-3 [nTPM]":"12.5","Cell RNA - SK-MEL-30 [nTPM]":"10.5","Cell RNA - SuSa [nTPM]":"23.0","Cell RNA - T-47d [nTPM]":"6.1","Cell RNA - THP-1 [nTPM]":"12.7","Cell RNA - TIME [nTPM]":"23.6","Cell RNA - U-138 MG [nTPM]":"13.6","Cell RNA - U-2 OS [nTPM]":"12.6","Cell RNA - U-2197 [nTPM]":"11.9","Cell RNA - U-251 MG [nTPM]":"13.6","Cell RNA - U-266\/70 [nTPM]":"9.4","Cell RNA - U-266\/84 [nTPM]":"17.4","Cell RNA - U-698 [nTPM]":"13.3","Cell RNA - U-87 MG [nTPM]":"7.8","Cell RNA - U-937 [nTPM]":"23.3","Cell RNA - WM-115 [nTPM]":"4.9","Blood RNA - basophil [nTPM]":"24.4","Blood RNA - classical monocyte [nTPM]":"3.8","Blood RNA - eosinophil [nTPM]":"8.7","Blood RNA - gdT-cell [nTPM]":"4.9","Blood RNA - intermediate monocyte [nTPM]":"3.4","Blood RNA - MAIT T-cell [nTPM]":"3.7","Blood RNA - memory B-cell [nTPM]":"5.9","Blood RNA - memory CD4 T-cell [nTPM]":"5.5","Blood RNA - memory CD8 T-cell [nTPM]":"4.6","Blood RNA - myeloid DC [nTPM]":"3.4","Blood RNA - naive B-cell [nTPM]":"9.5","Blood RNA - naive CD4 T-cell [nTPM]":"5.5","Blood RNA - naive CD8 T-cell [nTPM]":"5.4","Blood RNA - neutrophil [nTPM]":"13.5","Blood RNA - NK-cell [nTPM]":"2.9","Blood RNA - non-classical monocyte [nTPM]":"6.7","Blood RNA - plasmacytoid DC [nTPM]":"7.5","Blood RNA - T-reg [nTPM]":"7.8","Blood RNA - total PBMC [nTPM]":"1.8","Brain RNA - amygdala [nTPM]":"8.6","Brain RNA - basal ganglia [nTPM]":"10.1","Brain RNA - cerebellum [nTPM]":"14.1","Brain RNA - cerebral cortex [nTPM]":"20.3","Brain RNA - hippocampal formation [nTPM]":"9.3","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"1.7","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"1.8","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"22.7","Single Cell Type RNA - Adipocytes [nTPM]":"66.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"39.5","Single Cell Type RNA - Astrocytes [nTPM]":"113.0","Single Cell Type RNA - B-cells [nTPM]":"44.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Bipolar cells [nTPM]":"65.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"64.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"19.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"66.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.8","Single Cell Type RNA - dendritic cells [nTPM]":"66.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.0","Single Cell Type RNA - Early spermatids [nTPM]":"28.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"24.0","Single Cell Type RNA - Endothelial cells [nTPM]":"44.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.2","Single Cell Type RNA - Erythroid cells [nTPM]":"47.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"458.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.1","Single Cell Type RNA - Fibroblasts [nTPM]":"28.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"34.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.8","Single Cell Type RNA - granulocytes [nTPM]":"50.6","Single Cell Type RNA - Granulosa cells [nTPM]":"36.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"47.2","Single Cell Type RNA - Hepatocytes [nTPM]":"21.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.2","Single Cell Type RNA - Horizontal cells [nTPM]":"85.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"338.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.1","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"43.2","Single Cell Type RNA - Langerhans cells [nTPM]":"27.4","Single Cell Type RNA - Late spermatids [nTPM]":"14.3","Single Cell Type RNA - Leydig cells [nTPM]":"27.7","Single Cell Type RNA - Macrophages [nTPM]":"39.2","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"137.7","Single Cell Type RNA - monocytes [nTPM]":"36.0","Single Cell Type RNA - Muller glia cells [nTPM]":"29.9","Single Cell Type RNA - NK-cells [nTPM]":"35.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"160.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"201.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.7","Single Cell Type RNA - Paneth cells [nTPM]":"14.7","Single Cell Type RNA - Peritubular cells [nTPM]":"39.9","Single Cell Type RNA - Plasma cells [nTPM]":"44.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"55.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"34.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"36.0","Single Cell Type RNA - Spermatocytes [nTPM]":"43.5","Single Cell Type RNA - Spermatogonia [nTPM]":"31.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.9","Single Cell Type RNA - T-cells [nTPM]":"61.1","Single Cell Type RNA - Theca cells [nTPM]":"31.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.4","Single Cell Type RNA - Urothelial cells [nTPM]":"12.1"},{"Gene":"HERC2","Gene synonym":["D15F37S1","jdf2","p528"],"Ensembl":"ENSG00000128731","Gene description":"HECT and RLD domain containing E3 ubiquitin protein ligase 2","Uniprot":["O95714"],"Chromosome":"15","Position":"28111040-28322179","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["DNA damage","DNA repair","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"54.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017188","HPA048389","HPA074166"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB017188":null,"HPA048389":"AB_2680382","HPA074166":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.41e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.3","Tissue RNA - adrenal gland [nTPM]":"5.7","Tissue RNA - amygdala [nTPM]":"2.5","Tissue RNA - appendix [nTPM]":"2.3","Tissue RNA - basal ganglia [nTPM]":"2.9","Tissue RNA - bone marrow [nTPM]":"4.0","Tissue RNA - breast [nTPM]":"4.9","Tissue RNA - cerebellum [nTPM]":"1.5","Tissue RNA - cerebral cortex [nTPM]":"3.1","Tissue RNA - cervix [nTPM]":"5.5","Tissue RNA - choroid plexus [nTPM]":"3.0","Tissue RNA - colon [nTPM]":"9.3","Tissue RNA - duodenum [nTPM]":"2.6","Tissue RNA - endometrium 1 [nTPM]":"7.6","Tissue RNA - epididymis [nTPM]":"1.7","Tissue RNA - esophagus [nTPM]":"5.2","Tissue RNA - fallopian tube [nTPM]":"6.1","Tissue RNA - gallbladder [nTPM]":"2.2","Tissue RNA - heart muscle [nTPM]":"7.4","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"3.7","Tissue RNA - liver [nTPM]":"3.7","Tissue RNA - lung [nTPM]":"5.1","Tissue RNA - lymph node [nTPM]":"2.3","Tissue RNA - medulla oblongata [nTPM]":"2.0","Tissue RNA - midbrain [nTPM]":"1.8","Tissue RNA - ovary [nTPM]":"8.3","Tissue RNA - pancreas [nTPM]":"6.1","Tissue RNA - parathyroid gland [nTPM]":"5.4","Tissue RNA - pituitary gland [nTPM]":"6.3","Tissue RNA - placenta [nTPM]":"2.7","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"4.4","Tissue RNA - rectum [nTPM]":"2.8","Tissue RNA - retina [nTPM]":"5.3","Tissue RNA - salivary gland [nTPM]":"4.8","Tissue RNA - seminal vesicle [nTPM]":"2.9","Tissue RNA - skeletal muscle [nTPM]":"14.2","Tissue RNA - skin 1 [nTPM]":"5.3","Tissue RNA - small intestine [nTPM]":"6.1","Tissue RNA - smooth muscle [nTPM]":"3.7","Tissue RNA - spinal cord [nTPM]":"0.4","Tissue RNA - spleen [nTPM]":"4.3","Tissue RNA - stomach 1 [nTPM]":"6.3","Tissue RNA - testis [nTPM]":"4.8","Tissue RNA - thalamus [nTPM]":"2.7","Tissue RNA - thymus [nTPM]":"4.4","Tissue RNA - thyroid gland [nTPM]":"5.8","Tissue RNA - tongue [nTPM]":"9.3","Tissue RNA - tonsil [nTPM]":"2.4","Tissue RNA - urinary bladder [nTPM]":"5.6","Tissue RNA - vagina [nTPM]":"5.0","Tissue RNA - white matter [nTPM]":"6.2","Cell RNA - A-431 [nTPM]":"8.5","Cell RNA - A549 [nTPM]":"16.5","Cell RNA - AF22 [nTPM]":"11.2","Cell RNA - AN3-CA [nTPM]":"4.7","Cell RNA - ASC diff [nTPM]":"9.2","Cell RNA - ASC TERT1 [nTPM]":"6.9","Cell RNA - BEWO [nTPM]":"3.2","Cell RNA - BJ [nTPM]":"6.0","Cell RNA - BJ hTERT+ [nTPM]":"7.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.3","Cell RNA - CACO-2 [nTPM]":"8.6","Cell RNA - CAPAN-2 [nTPM]":"1.1","Cell RNA - Daudi [nTPM]":"8.5","Cell RNA - EFO-21 [nTPM]":"7.2","Cell RNA - fHDF\/TERT166 [nTPM]":"10.4","Cell RNA - GAMG [nTPM]":"11.5","Cell RNA - HaCaT [nTPM]":"8.5","Cell RNA - HAP1 [nTPM]":"12.0","Cell RNA - HBEC3-KT [nTPM]":"5.9","Cell RNA - HBF TERT88 [nTPM]":"5.6","Cell RNA - HDLM-2 [nTPM]":"5.2","Cell RNA - HEK 293 [nTPM]":"7.8","Cell RNA - HEL [nTPM]":"54.0","Cell RNA - HeLa [nTPM]":"20.2","Cell RNA - Hep G2 [nTPM]":"2.9","Cell RNA - HHSteC [nTPM]":"3.5","Cell RNA - HL-60 [nTPM]":"12.8","Cell RNA - HMC-1 [nTPM]":"4.1","Cell RNA - HSkMC [nTPM]":"5.7","Cell RNA - hTCEpi [nTPM]":"4.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.0","Cell RNA - hTERT-HME1 [nTPM]":"11.2","Cell RNA - hTERT-RPE1 [nTPM]":"4.9","Cell RNA - HUVEC TERT2 [nTPM]":"10.2","Cell RNA - JURKAT [nTPM]":"7.0","Cell RNA - K-562 [nTPM]":"21.2","Cell RNA - Karpas-707 [nTPM]":"3.4","Cell RNA - LHCN-M2 [nTPM]":"7.3","Cell RNA - MCF7 [nTPM]":"3.9","Cell RNA - MOLT-4 [nTPM]":"2.9","Cell RNA - NB-4 [nTPM]":"4.3","Cell RNA - NTERA-2 [nTPM]":"3.4","Cell RNA - OE19 [nTPM]":"6.4","Cell RNA - PC-3 [nTPM]":"7.1","Cell RNA - REH [nTPM]":"10.2","Cell RNA - RH-30 [nTPM]":"16.0","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"2.6","Cell RNA - RT4 [nTPM]":"18.2","Cell RNA - SCLC-21H [nTPM]":"12.3","Cell RNA - SH-SY5Y [nTPM]":"7.1","Cell RNA - SiHa [nTPM]":"14.6","Cell RNA - SK-BR-3 [nTPM]":"4.1","Cell RNA - SK-MEL-30 [nTPM]":"4.5","Cell RNA - SuSa [nTPM]":"5.8","Cell RNA - T-47d [nTPM]":"4.8","Cell RNA - THP-1 [nTPM]":"14.8","Cell RNA - TIME [nTPM]":"15.3","Cell RNA - U-138 MG [nTPM]":"14.0","Cell RNA - U-2 OS [nTPM]":"9.2","Cell RNA - U-2197 [nTPM]":"5.5","Cell RNA - U-251 MG [nTPM]":"9.1","Cell RNA - U-266\/70 [nTPM]":"2.2","Cell RNA - U-266\/84 [nTPM]":"3.3","Cell RNA - U-698 [nTPM]":"7.7","Cell RNA - U-87 MG [nTPM]":"6.5","Cell RNA - U-937 [nTPM]":"5.9","Cell RNA - WM-115 [nTPM]":"7.6","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"2.5","Brain RNA - basal ganglia [nTPM]":"2.9","Brain RNA - cerebellum [nTPM]":"1.5","Brain RNA - cerebral cortex [nTPM]":"3.1","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"2.0","Brain RNA - midbrain [nTPM]":"1.8","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"0.4","Brain RNA - thalamus [nTPM]":"2.7","Brain RNA - white matter [nTPM]":"6.2","Single Cell Type RNA - Adipocytes [nTPM]":"56.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.5","Single Cell Type RNA - Astrocytes [nTPM]":"68.9","Single Cell Type RNA - B-cells [nTPM]":"34.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"27.9","Single Cell Type RNA - Bipolar cells [nTPM]":"107.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"39.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"31.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"66.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"23.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"64.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"148.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.9","Single Cell Type RNA - dendritic cells [nTPM]":"28.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"31.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"28.7","Single Cell Type RNA - Early spermatids [nTPM]":"13.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"35.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"55.8","Single Cell Type RNA - Endothelial cells [nTPM]":"73.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"28.1","Single Cell Type RNA - Erythroid cells [nTPM]":"67.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"88.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.5","Single Cell Type RNA - Fibroblasts [nTPM]":"34.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"43.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"29.6","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"135.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"38.9","Single Cell Type RNA - Hepatocytes [nTPM]":"36.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.0","Single Cell Type RNA - Horizontal cells [nTPM]":"122.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"82.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"32.1","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"22.3","Single Cell Type RNA - Langerhans cells [nTPM]":"20.7","Single Cell Type RNA - Late spermatids [nTPM]":"15.8","Single Cell Type RNA - Leydig cells [nTPM]":"56.2","Single Cell Type RNA - Macrophages [nTPM]":"22.1","Single Cell Type RNA - Melanocytes [nTPM]":"69.4","Single Cell Type RNA - Microglial cells [nTPM]":"84.3","Single Cell Type RNA - monocytes [nTPM]":"26.9","Single Cell Type RNA - Muller glia cells [nTPM]":"41.0","Single Cell Type RNA - NK-cells [nTPM]":"45.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"65.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"89.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"36.6","Single Cell Type RNA - Paneth cells [nTPM]":"30.8","Single Cell Type RNA - Peritubular cells [nTPM]":"52.3","Single Cell Type RNA - Plasma cells [nTPM]":"56.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"31.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"142.9","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"46.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"43.2","Single Cell Type RNA - Spermatocytes [nTPM]":"72.5","Single Cell Type RNA - Spermatogonia [nTPM]":"66.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"38.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.8","Single Cell Type RNA - T-cells [nTPM]":"30.0","Single Cell Type RNA - Theca cells [nTPM]":"62.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"35.5","Single Cell Type RNA - Urothelial cells [nTPM]":"11.5"},{"Gene":"HEXA","Gene synonym":[],"Ensembl":"ENSG00000213614","Gene description":"Hexosaminidase subunit alpha","Uniprot":["P06865"],"Chromosome":"15","Position":"72340924-72376420","Protein class":["Candidate cardiovascular disease genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant","Gangliosidosis","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"234.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018082","HPA054583"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"20000000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA018082":null,"HPA054583":"AB_2682531"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.63e-8"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-2"},"Tissue RNA - adipose tissue [nTPM]":"49.8","Tissue RNA - adrenal gland [nTPM]":"56.1","Tissue RNA - amygdala [nTPM]":"18.3","Tissue RNA - appendix [nTPM]":"37.6","Tissue RNA - basal ganglia [nTPM]":"21.1","Tissue RNA - bone marrow [nTPM]":"110.0","Tissue RNA - breast [nTPM]":"58.5","Tissue RNA - cerebellum [nTPM]":"20.4","Tissue RNA - cerebral cortex [nTPM]":"21.6","Tissue RNA - cervix [nTPM]":"73.8","Tissue RNA - choroid plexus [nTPM]":"28.5","Tissue RNA - colon [nTPM]":"55.1","Tissue RNA - duodenum [nTPM]":"49.8","Tissue RNA - endometrium 1 [nTPM]":"42.6","Tissue RNA - epididymis [nTPM]":"164.6","Tissue RNA - esophagus [nTPM]":"24.8","Tissue RNA - fallopian tube [nTPM]":"47.8","Tissue RNA - gallbladder [nTPM]":"76.7","Tissue RNA - heart muscle [nTPM]":"54.3","Tissue RNA - hippocampal formation [nTPM]":"19.9","Tissue RNA - hypothalamus [nTPM]":"20.1","Tissue RNA - kidney [nTPM]":"90.1","Tissue RNA - liver [nTPM]":"79.4","Tissue RNA - lung [nTPM]":"84.2","Tissue RNA - lymph node [nTPM]":"54.2","Tissue RNA - medulla oblongata [nTPM]":"23.0","Tissue RNA - midbrain [nTPM]":"21.3","Tissue RNA - ovary [nTPM]":"39.3","Tissue RNA - pancreas [nTPM]":"30.6","Tissue RNA - parathyroid gland [nTPM]":"54.0","Tissue RNA - pituitary gland [nTPM]":"26.3","Tissue RNA - placenta [nTPM]":"102.0","Tissue RNA - pons [nTPM]":"24.6","Tissue RNA - prostate [nTPM]":"45.3","Tissue RNA - rectum [nTPM]":"67.0","Tissue RNA - retina [nTPM]":"32.1","Tissue RNA - salivary gland [nTPM]":"45.0","Tissue RNA - seminal vesicle [nTPM]":"53.3","Tissue RNA - skeletal muscle [nTPM]":"22.1","Tissue RNA - skin 1 [nTPM]":"21.8","Tissue RNA - small intestine [nTPM]":"41.2","Tissue RNA - smooth muscle [nTPM]":"59.5","Tissue RNA - spinal cord [nTPM]":"21.7","Tissue RNA - spleen [nTPM]":"54.7","Tissue RNA - stomach 1 [nTPM]":"45.1","Tissue RNA - testis [nTPM]":"35.6","Tissue RNA - thalamus [nTPM]":"27.0","Tissue RNA - thymus [nTPM]":"38.1","Tissue RNA - thyroid gland [nTPM]":"76.5","Tissue RNA - tongue [nTPM]":"33.2","Tissue RNA - tonsil [nTPM]":"42.4","Tissue RNA - urinary bladder [nTPM]":"71.6","Tissue RNA - vagina [nTPM]":"19.7","Tissue RNA - white matter [nTPM]":"29.9","Cell RNA - A-431 [nTPM]":"39.8","Cell RNA - A549 [nTPM]":"66.4","Cell RNA - AF22 [nTPM]":"27.8","Cell RNA - AN3-CA [nTPM]":"53.8","Cell RNA - ASC diff [nTPM]":"223.6","Cell RNA - ASC TERT1 [nTPM]":"253.1","Cell RNA - BEWO [nTPM]":"39.7","Cell RNA - BJ [nTPM]":"54.8","Cell RNA - BJ hTERT+ [nTPM]":"274.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"115.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"182.8","Cell RNA - CACO-2 [nTPM]":"34.6","Cell RNA - CAPAN-2 [nTPM]":"282.7","Cell RNA - Daudi [nTPM]":"32.9","Cell RNA - EFO-21 [nTPM]":"50.9","Cell RNA - fHDF\/TERT166 [nTPM]":"110.0","Cell RNA - GAMG [nTPM]":"59.9","Cell RNA - HaCaT [nTPM]":"77.1","Cell RNA - HAP1 [nTPM]":"74.5","Cell RNA - HBEC3-KT [nTPM]":"34.6","Cell RNA - HBF TERT88 [nTPM]":"72.5","Cell RNA - HDLM-2 [nTPM]":"26.5","Cell RNA - HEK 293 [nTPM]":"30.0","Cell RNA - HEL [nTPM]":"41.4","Cell RNA - HeLa [nTPM]":"60.4","Cell RNA - Hep G2 [nTPM]":"60.9","Cell RNA - HHSteC [nTPM]":"172.9","Cell RNA - HL-60 [nTPM]":"99.9","Cell RNA - HMC-1 [nTPM]":"113.1","Cell RNA - HSkMC [nTPM]":"216.7","Cell RNA - hTCEpi [nTPM]":"101.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"50.4","Cell RNA - hTERT-HME1 [nTPM]":"89.3","Cell RNA - hTERT-RPE1 [nTPM]":"210.3","Cell RNA - HUVEC TERT2 [nTPM]":"107.4","Cell RNA - JURKAT [nTPM]":"48.4","Cell RNA - K-562 [nTPM]":"65.1","Cell RNA - Karpas-707 [nTPM]":"197.6","Cell RNA - LHCN-M2 [nTPM]":"156.0","Cell RNA - MCF7 [nTPM]":"33.9","Cell RNA - MOLT-4 [nTPM]":"21.7","Cell RNA - NB-4 [nTPM]":"50.0","Cell RNA - NTERA-2 [nTPM]":"16.0","Cell RNA - OE19 [nTPM]":"128.9","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"22.3","Cell RNA - RH-30 [nTPM]":"60.6","Cell RNA - RPMI-8226 [nTPM]":"75.3","Cell RNA - RPTEC TERT1 [nTPM]":"129.1","Cell RNA - RT4 [nTPM]":"61.6","Cell RNA - SCLC-21H [nTPM]":"23.8","Cell RNA - SH-SY5Y [nTPM]":"26.4","Cell RNA - SiHa [nTPM]":"136.5","Cell RNA - SK-BR-3 [nTPM]":"126.6","Cell RNA - SK-MEL-30 [nTPM]":"307.3","Cell RNA - SuSa [nTPM]":"56.1","Cell RNA - T-47d [nTPM]":"23.4","Cell RNA - THP-1 [nTPM]":"123.9","Cell RNA - TIME [nTPM]":"54.1","Cell RNA - U-138 MG [nTPM]":"171.9","Cell RNA - U-2 OS [nTPM]":"70.7","Cell RNA - U-2197 [nTPM]":"160.1","Cell RNA - U-251 MG [nTPM]":"59.3","Cell RNA - U-266\/70 [nTPM]":"104.7","Cell RNA - U-266\/84 [nTPM]":"151.8","Cell RNA - U-698 [nTPM]":"33.4","Cell RNA - U-87 MG [nTPM]":"62.1","Cell RNA - U-937 [nTPM]":"130.4","Cell RNA - WM-115 [nTPM]":"85.3","Blood RNA - basophil [nTPM]":"24.2","Blood RNA - classical monocyte [nTPM]":"84.6","Blood RNA - eosinophil [nTPM]":"60.1","Blood RNA - gdT-cell [nTPM]":"43.8","Blood RNA - intermediate monocyte [nTPM]":"35.7","Blood RNA - MAIT T-cell [nTPM]":"38.7","Blood RNA - memory B-cell [nTPM]":"41.1","Blood RNA - memory CD4 T-cell [nTPM]":"28.8","Blood RNA - memory CD8 T-cell [nTPM]":"38.9","Blood RNA - myeloid DC [nTPM]":"98.0","Blood RNA - naive B-cell [nTPM]":"38.0","Blood RNA - naive CD4 T-cell [nTPM]":"22.5","Blood RNA - naive CD8 T-cell [nTPM]":"33.2","Blood RNA - neutrophil [nTPM]":"8.1","Blood RNA - NK-cell [nTPM]":"51.3","Blood RNA - non-classical monocyte [nTPM]":"13.3","Blood RNA - plasmacytoid DC [nTPM]":"37.3","Blood RNA - T-reg [nTPM]":"28.2","Blood RNA - total PBMC [nTPM]":"63.0","Brain RNA - amygdala [nTPM]":"18.3","Brain RNA - basal ganglia [nTPM]":"21.1","Brain RNA - cerebellum [nTPM]":"20.4","Brain RNA - cerebral cortex [nTPM]":"21.6","Brain RNA - hippocampal formation [nTPM]":"19.9","Brain RNA - hypothalamus [nTPM]":"20.1","Brain RNA - medulla oblongata [nTPM]":"23.0","Brain RNA - midbrain [nTPM]":"21.3","Brain RNA - pons [nTPM]":"24.6","Brain RNA - spinal cord [nTPM]":"21.7","Brain RNA - thalamus [nTPM]":"27.0","Brain RNA - white matter [nTPM]":"29.9","Single Cell Type RNA - Adipocytes [nTPM]":"68.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"64.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"62.4","Single Cell Type RNA - Astrocytes [nTPM]":"19.9","Single Cell Type RNA - B-cells [nTPM]":"46.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"22.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"33.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"94.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.4","Single Cell Type RNA - Bipolar cells [nTPM]":"42.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"28.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"26.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"68.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"66.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"106.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"150.2","Single Cell Type RNA - dendritic cells [nTPM]":"54.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"36.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"60.7","Single Cell Type RNA - Ductal cells [nTPM]":"88.3","Single Cell Type RNA - Early spermatids [nTPM]":"20.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"30.2","Single Cell Type RNA - Endothelial cells [nTPM]":"50.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"47.2","Single Cell Type RNA - Erythroid cells [nTPM]":"19.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"38.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"68.0","Single Cell Type RNA - Fibroblasts [nTPM]":"78.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"42.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"40.6","Single Cell Type RNA - granulocytes [nTPM]":"29.9","Single Cell Type RNA - Granulosa cells [nTPM]":"49.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"43.5","Single Cell Type RNA - Hepatocytes [nTPM]":"42.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"234.3","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"46.3","Single Cell Type RNA - Ionocytes [nTPM]":"81.4","Single Cell Type RNA - Kupffer cells [nTPM]":"92.8","Single Cell Type RNA - Langerhans cells [nTPM]":"75.0","Single Cell Type RNA - Late spermatids [nTPM]":"13.7","Single Cell Type RNA - Leydig cells [nTPM]":"74.3","Single Cell Type RNA - Macrophages [nTPM]":"118.1","Single Cell Type RNA - Melanocytes [nTPM]":"94.3","Single Cell Type RNA - Microglial cells [nTPM]":"24.4","Single Cell Type RNA - monocytes [nTPM]":"60.3","Single Cell Type RNA - Muller glia cells [nTPM]":"38.4","Single Cell Type RNA - NK-cells [nTPM]":"82.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"26.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"39.1","Single Cell Type RNA - Paneth cells [nTPM]":"74.6","Single Cell Type RNA - Peritubular cells [nTPM]":"44.8","Single Cell Type RNA - Plasma cells [nTPM]":"37.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"33.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"68.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"66.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"37.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"56.9","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"24.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"31.7","Single Cell Type RNA - Spermatocytes [nTPM]":"24.3","Single Cell Type RNA - Spermatogonia [nTPM]":"32.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"157.6","Single Cell Type RNA - T-cells [nTPM]":"36.7","Single Cell Type RNA - Theca cells [nTPM]":"45.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"50.6","Single Cell Type RNA - Urothelial cells [nTPM]":"27.5"},{"Gene":"HEXB","Gene synonym":[],"Ensembl":"ENSG00000049860","Gene description":"Hexosaminidase subunit beta","Uniprot":["P07686"],"Chromosome":"5","Position":"74640023-74722647","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant","Gangliosidosis","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"466.5","Hofbauer cells":"340.2","Syncytiotrophoblasts":"493.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"746.0","GAMG":"646.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055409","HPA056010"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"40000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA055409":"AB_2682808","HPA056010":"AB_2683008"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.36e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Tissue RNA - adipose tissue [nTPM]":"92.2","Tissue RNA - adrenal gland [nTPM]":"72.0","Tissue RNA - amygdala [nTPM]":"22.1","Tissue RNA - appendix [nTPM]":"59.7","Tissue RNA - basal ganglia [nTPM]":"25.3","Tissue RNA - bone marrow [nTPM]":"59.9","Tissue RNA - breast [nTPM]":"83.0","Tissue RNA - cerebellum [nTPM]":"22.3","Tissue RNA - cerebral cortex [nTPM]":"32.5","Tissue RNA - cervix [nTPM]":"97.6","Tissue RNA - choroid plexus [nTPM]":"39.4","Tissue RNA - colon [nTPM]":"105.0","Tissue RNA - duodenum [nTPM]":"99.0","Tissue RNA - endometrium 1 [nTPM]":"71.5","Tissue RNA - epididymis [nTPM]":"321.4","Tissue RNA - esophagus [nTPM]":"38.5","Tissue RNA - fallopian tube [nTPM]":"66.7","Tissue RNA - gallbladder [nTPM]":"99.0","Tissue RNA - heart muscle [nTPM]":"84.3","Tissue RNA - hippocampal formation [nTPM]":"23.1","Tissue RNA - hypothalamus [nTPM]":"26.2","Tissue RNA - kidney [nTPM]":"81.6","Tissue RNA - liver [nTPM]":"137.5","Tissue RNA - lung [nTPM]":"111.3","Tissue RNA - lymph node [nTPM]":"47.0","Tissue RNA - medulla oblongata [nTPM]":"23.8","Tissue RNA - midbrain [nTPM]":"22.9","Tissue RNA - ovary [nTPM]":"62.4","Tissue RNA - pancreas [nTPM]":"103.6","Tissue RNA - parathyroid gland [nTPM]":"94.2","Tissue RNA - pituitary gland [nTPM]":"46.6","Tissue RNA - placenta [nTPM]":"319.4","Tissue RNA - pons [nTPM]":"24.7","Tissue RNA - prostate [nTPM]":"98.7","Tissue RNA - rectum [nTPM]":"116.9","Tissue RNA - retina [nTPM]":"33.6","Tissue RNA - salivary gland [nTPM]":"123.4","Tissue RNA - seminal vesicle [nTPM]":"54.0","Tissue RNA - skeletal muscle [nTPM]":"43.3","Tissue RNA - skin 1 [nTPM]":"54.3","Tissue RNA - small intestine [nTPM]":"75.4","Tissue RNA - smooth muscle [nTPM]":"76.1","Tissue RNA - spinal cord [nTPM]":"23.2","Tissue RNA - spleen [nTPM]":"64.7","Tissue RNA - stomach 1 [nTPM]":"88.4","Tissue RNA - testis [nTPM]":"19.6","Tissue RNA - thalamus [nTPM]":"28.2","Tissue RNA - thymus [nTPM]":"29.1","Tissue RNA - thyroid gland [nTPM]":"89.6","Tissue RNA - tongue [nTPM]":"38.4","Tissue RNA - tonsil [nTPM]":"40.4","Tissue RNA - urinary bladder [nTPM]":"94.6","Tissue RNA - vagina [nTPM]":"64.1","Tissue RNA - white matter [nTPM]":"30.4","Cell RNA - A-431 [nTPM]":"147.3","Cell RNA - A549 [nTPM]":"111.0","Cell RNA - AF22 [nTPM]":"39.4","Cell RNA - AN3-CA [nTPM]":"131.8","Cell RNA - ASC diff [nTPM]":"746.0","Cell RNA - ASC TERT1 [nTPM]":"232.3","Cell RNA - BEWO [nTPM]":"122.3","Cell RNA - BJ [nTPM]":"173.5","Cell RNA - BJ hTERT+ [nTPM]":"590.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"175.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"375.2","Cell RNA - CACO-2 [nTPM]":"130.6","Cell RNA - CAPAN-2 [nTPM]":"194.5","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"133.0","Cell RNA - fHDF\/TERT166 [nTPM]":"152.2","Cell RNA - GAMG [nTPM]":"646.3","Cell RNA - HaCaT [nTPM]":"115.2","Cell RNA - HAP1 [nTPM]":"43.2","Cell RNA - HBEC3-KT [nTPM]":"185.2","Cell RNA - HBF TERT88 [nTPM]":"228.7","Cell RNA - HDLM-2 [nTPM]":"79.2","Cell RNA - HEK 293 [nTPM]":"72.6","Cell RNA - HEL [nTPM]":"19.1","Cell RNA - HeLa [nTPM]":"101.4","Cell RNA - Hep G2 [nTPM]":"101.5","Cell RNA - HHSteC [nTPM]":"216.5","Cell RNA - HL-60 [nTPM]":"16.2","Cell RNA - HMC-1 [nTPM]":"152.3","Cell RNA - HSkMC [nTPM]":"206.7","Cell RNA - hTCEpi [nTPM]":"108.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"180.7","Cell RNA - hTERT-HME1 [nTPM]":"121.3","Cell RNA - hTERT-RPE1 [nTPM]":"275.9","Cell RNA - HUVEC TERT2 [nTPM]":"204.5","Cell RNA - JURKAT [nTPM]":"47.3","Cell RNA - K-562 [nTPM]":"54.3","Cell RNA - Karpas-707 [nTPM]":"236.9","Cell RNA - LHCN-M2 [nTPM]":"194.9","Cell RNA - MCF7 [nTPM]":"145.7","Cell RNA - MOLT-4 [nTPM]":"19.8","Cell RNA - NB-4 [nTPM]":"36.6","Cell RNA - NTERA-2 [nTPM]":"36.8","Cell RNA - OE19 [nTPM]":"142.7","Cell RNA - PC-3 [nTPM]":"47.8","Cell RNA - REH [nTPM]":"43.9","Cell RNA - RH-30 [nTPM]":"56.2","Cell RNA - RPMI-8226 [nTPM]":"191.8","Cell RNA - RPTEC TERT1 [nTPM]":"119.8","Cell RNA - RT4 [nTPM]":"130.4","Cell RNA - SCLC-21H [nTPM]":"24.5","Cell RNA - SH-SY5Y [nTPM]":"30.4","Cell RNA - SiHa [nTPM]":"134.2","Cell RNA - SK-BR-3 [nTPM]":"92.6","Cell RNA - SK-MEL-30 [nTPM]":"180.0","Cell RNA - SuSa [nTPM]":"68.8","Cell RNA - T-47d [nTPM]":"99.1","Cell RNA - THP-1 [nTPM]":"108.6","Cell RNA - TIME [nTPM]":"118.5","Cell RNA - U-138 MG [nTPM]":"112.1","Cell RNA - U-2 OS [nTPM]":"26.6","Cell RNA - U-2197 [nTPM]":"207.8","Cell RNA - U-251 MG [nTPM]":"165.6","Cell RNA - U-266\/70 [nTPM]":"102.6","Cell RNA - U-266\/84 [nTPM]":"191.3","Cell RNA - U-698 [nTPM]":"0.9","Cell RNA - U-87 MG [nTPM]":"257.9","Cell RNA - U-937 [nTPM]":"143.6","Cell RNA - WM-115 [nTPM]":"209.8","Blood RNA - basophil [nTPM]":"86.2","Blood RNA - classical monocyte [nTPM]":"343.2","Blood RNA - eosinophil [nTPM]":"99.1","Blood RNA - gdT-cell [nTPM]":"69.3","Blood RNA - intermediate monocyte [nTPM]":"129.9","Blood RNA - MAIT T-cell [nTPM]":"80.7","Blood RNA - memory B-cell [nTPM]":"45.2","Blood RNA - memory CD4 T-cell [nTPM]":"56.1","Blood RNA - memory CD8 T-cell [nTPM]":"64.0","Blood RNA - myeloid DC [nTPM]":"310.8","Blood RNA - naive B-cell [nTPM]":"28.1","Blood RNA - naive CD4 T-cell [nTPM]":"52.6","Blood RNA - naive CD8 T-cell [nTPM]":"51.3","Blood RNA - neutrophil [nTPM]":"125.2","Blood RNA - NK-cell [nTPM]":"42.4","Blood RNA - non-classical monocyte [nTPM]":"82.5","Blood RNA - plasmacytoid DC [nTPM]":"93.4","Blood RNA - T-reg [nTPM]":"73.2","Blood RNA - total PBMC [nTPM]":"269.0","Brain RNA - amygdala [nTPM]":"22.1","Brain RNA - basal ganglia [nTPM]":"25.3","Brain RNA - cerebellum [nTPM]":"22.3","Brain RNA - cerebral cortex [nTPM]":"32.5","Brain RNA - hippocampal formation [nTPM]":"23.1","Brain RNA - hypothalamus [nTPM]":"26.2","Brain RNA - medulla oblongata [nTPM]":"23.8","Brain RNA - midbrain [nTPM]":"22.9","Brain RNA - pons [nTPM]":"24.7","Brain RNA - spinal cord [nTPM]":"23.2","Brain RNA - thalamus [nTPM]":"28.2","Brain RNA - white matter [nTPM]":"30.4","Single Cell Type RNA - Adipocytes [nTPM]":"49.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"38.4","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"31.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"44.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"82.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"103.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.6","Single Cell Type RNA - Bipolar cells [nTPM]":"10.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"27.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"82.9","Single Cell Type RNA - Club cells [nTPM]":"63.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"466.5","Single Cell Type RNA - dendritic cells [nTPM]":"32.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"68.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"151.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"21.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.4","Single Cell Type RNA - Endothelial cells [nTPM]":"56.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.8","Single Cell Type RNA - Erythroid cells [nTPM]":"23.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"32.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"125.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"175.4","Single Cell Type RNA - Fibroblasts [nTPM]":"107.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"33.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.9","Single Cell Type RNA - granulocytes [nTPM]":"69.8","Single Cell Type RNA - Granulosa cells [nTPM]":"19.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"74.3","Single Cell Type RNA - Hepatocytes [nTPM]":"70.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"340.2","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"56.7","Single Cell Type RNA - Ionocytes [nTPM]":"107.8","Single Cell Type RNA - Kupffer cells [nTPM]":"127.3","Single Cell Type RNA - Langerhans cells [nTPM]":"134.3","Single Cell Type RNA - Late spermatids [nTPM]":"3.4","Single Cell Type RNA - Leydig cells [nTPM]":"85.1","Single Cell Type RNA - Macrophages [nTPM]":"168.8","Single Cell Type RNA - Melanocytes [nTPM]":"72.9","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"114.2","Single Cell Type RNA - Muller glia cells [nTPM]":"35.4","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"13.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"65.8","Single Cell Type RNA - Paneth cells [nTPM]":"54.8","Single Cell Type RNA - Peritubular cells [nTPM]":"72.2","Single Cell Type RNA - Plasma cells [nTPM]":"71.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"74.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"99.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"79.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"36.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.3","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"32.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"49.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"32.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"493.6","Single Cell Type RNA - T-cells [nTPM]":"35.3","Single Cell Type RNA - Theca cells [nTPM]":"31.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"81.8","Single Cell Type RNA - Urothelial cells [nTPM]":"71.0"},{"Gene":"HFM1","Gene synonym":["FLJ36760","FLJ39011","MER3","SEC63D1"],"Ensembl":"ENSG00000162669","Gene description":"Helicase for meiosis 1","Uniprot":["A2PYH4"],"Chromosome":"1","Position":"91260766-91404856","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Meiosis"],"Molecular function":["Helicase","Hydrolase"],"Disease involvement":["Disease variant","Premature ovarian failure"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pituitary gland":"9.3","testis":"13.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"50.9","Inhibitory neurons":"38.4","Oligodendrocyte precursor cells":"90.5","Spermatocytes":"58.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"0.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"5.2","AN3-CA":"2.8","K-562":"3.0","SH-SY5Y":"2.1","U-266\/70":"2.7"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035036","HPA035557"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA035036":"AB_2797224","HPA035557":"AB_10696507"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.59e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"1.0","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"1.0","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"5.1","Tissue RNA - cerebral cortex [nTPM]":"1.0","Tissue RNA - cervix [nTPM]":"0.9","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.5","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"2.3","Tissue RNA - epididymis [nTPM]":"1.1","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.8","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"0.6","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"1.6","Tissue RNA - kidney [nTPM]":"0.7","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"1.7","Tissue RNA - midbrain [nTPM]":"1.6","Tissue RNA - ovary [nTPM]":"3.9","Tissue RNA - pancreas [nTPM]":"0.7","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"9.3","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"1.1","Tissue RNA - prostate [nTPM]":"0.6","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"4.5","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"1.1","Tissue RNA - skeletal muscle [nTPM]":"1.5","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.9","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"13.8","Tissue RNA - thalamus [nTPM]":"1.6","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"1.6","Tissue RNA - tongue [nTPM]":"1.1","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"1.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"5.2","Cell RNA - AN3-CA [nTPM]":"2.8","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.0","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.7","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"3.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"1.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"1.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.7","Cell RNA - SH-SY5Y [nTPM]":"2.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.7","Cell RNA - SuSa [nTPM]":"1.4","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"2.7","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.0","Brain RNA - basal ganglia [nTPM]":"1.0","Brain RNA - cerebellum [nTPM]":"5.1","Brain RNA - cerebral cortex [nTPM]":"1.0","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"1.6","Brain RNA - medulla oblongata [nTPM]":"1.7","Brain RNA - midbrain [nTPM]":"1.6","Brain RNA - pons [nTPM]":"1.1","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"1.6","Brain RNA - white matter [nTPM]":"1.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"50.9","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"3.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"17.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.9","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"5.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"38.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"5.0","Single Cell Type RNA - Leydig cells [nTPM]":"4.1","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"90.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.4","Single Cell Type RNA - Spermatocytes [nTPM]":"58.9","Single Cell Type RNA - Spermatogonia [nTPM]":"15.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"1.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"HGD","Gene synonym":["AKU","HGO"],"Ensembl":"ENSG00000113924","Gene description":"Homogentisate 1,2-dioxygenase","Uniprot":["Q93099"],"Chromosome":"3","Position":"120628172-120682269","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Phenylalanine catabolism","Tyrosine catabolism"],"Molecular function":["Dioxygenase","Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"kidney":"200.3","liver":"752.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"103.7","Endometrial ciliated cells":"113.9","Glandular and luminal cells":"127.8","Hepatocytes":"534.7","Proximal tubular cells":"477.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"liver cancer":"119.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"neutrophil":"1.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"1.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"55.8","EFO-21":"82.7","Hep G2":"186.6","OE19":"328.0","RPTEC TERT1":"212.2"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"1.2"},"Antibody":["HPA047374","HPA052359"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"700000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA047374":"AB_2680019","HPA052359":"AB_2681798"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.78e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"2.5","Tissue RNA - basal ganglia [nTPM]":"1.9","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"12.5","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"0.8","Tissue RNA - cervix [nTPM]":"27.4","Tissue RNA - choroid plexus [nTPM]":"1.5","Tissue RNA - colon [nTPM]":"16.7","Tissue RNA - duodenum [nTPM]":"31.6","Tissue RNA - endometrium 1 [nTPM]":"3.1","Tissue RNA - epididymis [nTPM]":"13.0","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"4.2","Tissue RNA - gallbladder [nTPM]":"61.7","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.4","Tissue RNA - kidney [nTPM]":"200.3","Tissue RNA - liver [nTPM]":"752.6","Tissue RNA - lung [nTPM]":"0.8","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"31.2","Tissue RNA - parathyroid gland [nTPM]":"7.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"44.5","Tissue RNA - rectum [nTPM]":"20.3","Tissue RNA - retina [nTPM]":"0.7","Tissue RNA - salivary gland [nTPM]":"4.2","Tissue RNA - seminal vesicle [nTPM]":"4.2","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"25.6","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"0.4","Tissue RNA - spleen [nTPM]":"0.6","Tissue RNA - stomach 1 [nTPM]":"25.5","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.5","Tissue RNA - thymus [nTPM]":"0.7","Tissue RNA - thyroid gland [nTPM]":"55.1","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"12.3","Cell RNA - AF22 [nTPM]":"4.6","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.6","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"55.8","Cell RNA - CAPAN-2 [nTPM]":"10.7","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"82.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"2.3","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"186.6","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"1.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"328.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"212.2","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.9","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"1.0","Cell RNA - TIME [nTPM]":"0.6","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.8","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"2.3","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"1.9","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"0.8","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.4","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.4","Brain RNA - thalamus [nTPM]":"0.5","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"5.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"81.5","Single Cell Type RNA - Club cells [nTPM]":"4.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"103.7","Single Cell Type RNA - Ductal cells [nTPM]":"7.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"113.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"43.8","Single Cell Type RNA - Erythroid cells [nTPM]":"24.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"127.8","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.4","Single Cell Type RNA - Hepatocytes [nTPM]":"534.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"16.1","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"21.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"2.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.1","Single Cell Type RNA - Paneth cells [nTPM]":"35.6","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"54.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"477.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"3.8","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"HGF","Gene synonym":["DFNB39","F-TCF","HGFB","HPTA","SF"],"Ensembl":"ENSG00000019991","Gene description":"Hepatocyte growth factor","Uniprot":["P14210"],"Chromosome":"7","Position":"81699010-81770438","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Growth factor","Serine protease homolog"],"Disease involvement":["Cancer-related genes","Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"placenta":"311.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"23.8","Fibroblasts":"95.8","Hepatic stellate cells":"25.0","Muller glia cells":"36.2","Smooth muscle cells":"26.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"94.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"94.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC TERT1":"171.6","HHSteC":"135.8","HL-60":"82.4","hTEC\/SVTERT24-B":"87.4","Karpas-707":"240.7","U-87 MG":"62.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010333","HPA040360","HPA044088"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":4110000,"Blood concentration - Conc. blood MS [pg\/L]":"14000","Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB010333":"AB_647965","HPA040360":"AB_2676939","HPA044088":"AB_2678804"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.59e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.9","Tissue RNA - adrenal gland [nTPM]":"19.8","Tissue RNA - amygdala [nTPM]":"1.6","Tissue RNA - appendix [nTPM]":"6.3","Tissue RNA - basal ganglia [nTPM]":"3.3","Tissue RNA - bone marrow [nTPM]":"12.3","Tissue RNA - breast [nTPM]":"5.2","Tissue RNA - cerebellum [nTPM]":"1.5","Tissue RNA - cerebral cortex [nTPM]":"7.8","Tissue RNA - cervix [nTPM]":"7.2","Tissue RNA - choroid plexus [nTPM]":"1.8","Tissue RNA - colon [nTPM]":"4.4","Tissue RNA - duodenum [nTPM]":"2.6","Tissue RNA - endometrium 1 [nTPM]":"8.1","Tissue RNA - epididymis [nTPM]":"3.6","Tissue RNA - esophagus [nTPM]":"2.9","Tissue RNA - fallopian tube [nTPM]":"5.4","Tissue RNA - gallbladder [nTPM]":"16.6","Tissue RNA - heart muscle [nTPM]":"4.7","Tissue RNA - hippocampal formation [nTPM]":"2.9","Tissue RNA - hypothalamus [nTPM]":"3.6","Tissue RNA - kidney [nTPM]":"11.8","Tissue RNA - liver [nTPM]":"30.3","Tissue RNA - lung [nTPM]":"19.5","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"3.6","Tissue RNA - midbrain [nTPM]":"2.3","Tissue RNA - ovary [nTPM]":"1.8","Tissue RNA - pancreas [nTPM]":"2.1","Tissue RNA - parathyroid gland [nTPM]":"2.1","Tissue RNA - pituitary gland [nTPM]":"2.4","Tissue RNA - placenta [nTPM]":"311.9","Tissue RNA - pons [nTPM]":"4.3","Tissue RNA - prostate [nTPM]":"7.2","Tissue RNA - rectum [nTPM]":"3.4","Tissue RNA - retina [nTPM]":"14.2","Tissue RNA - salivary gland [nTPM]":"2.4","Tissue RNA - seminal vesicle [nTPM]":"6.4","Tissue RNA - skeletal muscle [nTPM]":"0.8","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"2.3","Tissue RNA - smooth muscle [nTPM]":"7.1","Tissue RNA - spinal cord [nTPM]":"1.8","Tissue RNA - spleen [nTPM]":"6.5","Tissue RNA - stomach 1 [nTPM]":"3.9","Tissue RNA - testis [nTPM]":"2.4","Tissue RNA - thalamus [nTPM]":"2.9","Tissue RNA - thymus [nTPM]":"1.5","Tissue RNA - thyroid gland [nTPM]":"5.6","Tissue RNA - tongue [nTPM]":"3.9","Tissue RNA - tonsil [nTPM]":"1.5","Tissue RNA - urinary bladder [nTPM]":"10.4","Tissue RNA - vagina [nTPM]":"6.3","Tissue RNA - white matter [nTPM]":"3.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"21.6","Cell RNA - ASC TERT1 [nTPM]":"171.6","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.7","Cell RNA - BJ hTERT+ [nTPM]":"33.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.8","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"6.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"135.8","Cell RNA - HL-60 [nTPM]":"82.4","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"41.4","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"87.4","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"2.2","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"240.7","Cell RNA - LHCN-M2 [nTPM]":"0.6","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"56.4","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.8","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"7.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"9.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"3.5","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"2.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"62.6","Cell RNA - U-937 [nTPM]":"16.9","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"94.0","Blood RNA - classical monocyte [nTPM]":"15.2","Blood RNA - eosinophil [nTPM]":"3.9","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"18.7","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"4.8","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"3.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"17.3","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"4.3","Brain RNA - amygdala [nTPM]":"1.6","Brain RNA - basal ganglia [nTPM]":"3.3","Brain RNA - cerebellum [nTPM]":"1.5","Brain RNA - cerebral cortex [nTPM]":"7.8","Brain RNA - hippocampal formation [nTPM]":"2.9","Brain RNA - hypothalamus [nTPM]":"3.6","Brain RNA - medulla oblongata [nTPM]":"3.6","Brain RNA - midbrain [nTPM]":"2.3","Brain RNA - pons [nTPM]":"4.3","Brain RNA - spinal cord [nTPM]":"1.8","Brain RNA - thalamus [nTPM]":"2.9","Brain RNA - white matter [nTPM]":"3.3","Single Cell Type RNA - Adipocytes [nTPM]":"6.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.1","Single Cell Type RNA - Astrocytes [nTPM]":"16.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"15.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.8","Single Cell Type RNA - Endothelial cells [nTPM]":"6.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.9","Single Cell Type RNA - Fibroblasts [nTPM]":"95.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.9","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"12.5","Single Cell Type RNA - Langerhans cells [nTPM]":"1.9","Single Cell Type RNA - Late spermatids [nTPM]":"2.3","Single Cell Type RNA - Leydig cells [nTPM]":"18.3","Single Cell Type RNA - Macrophages [nTPM]":"14.0","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"10.5","Single Cell Type RNA - Muller glia cells [nTPM]":"36.2","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"10.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.0","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"1.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"HGSNAT","Gene synonym":["FLJ32731","HGNAT","TMEM76"],"Ensembl":"ENSG00000165102","Gene description":"Heparan-alpha-glucosaminide N-acetyltransferase","Uniprot":["Q68CP4"],"Chromosome":"8","Position":"43140464-43202855","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant","Mucopolysaccharidosis","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029578"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029578":"AB_10602423"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.46e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.33e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Tissue RNA - adipose tissue [nTPM]":"32.3","Tissue RNA - adrenal gland [nTPM]":"20.0","Tissue RNA - amygdala [nTPM]":"13.1","Tissue RNA - appendix [nTPM]":"17.5","Tissue RNA - basal ganglia [nTPM]":"13.0","Tissue RNA - bone marrow [nTPM]":"21.7","Tissue RNA - breast [nTPM]":"27.8","Tissue RNA - cerebellum [nTPM]":"10.6","Tissue RNA - cerebral cortex [nTPM]":"13.5","Tissue RNA - cervix [nTPM]":"35.0","Tissue RNA - choroid plexus [nTPM]":"13.8","Tissue RNA - colon [nTPM]":"25.4","Tissue RNA - duodenum [nTPM]":"18.4","Tissue RNA - endometrium 1 [nTPM]":"30.1","Tissue RNA - epididymis [nTPM]":"30.6","Tissue RNA - esophagus [nTPM]":"24.0","Tissue RNA - fallopian tube [nTPM]":"29.0","Tissue RNA - gallbladder [nTPM]":"25.9","Tissue RNA - heart muscle [nTPM]":"23.3","Tissue RNA - hippocampal formation [nTPM]":"13.3","Tissue RNA - hypothalamus [nTPM]":"17.6","Tissue RNA - kidney [nTPM]":"20.0","Tissue RNA - liver [nTPM]":"26.6","Tissue RNA - lung [nTPM]":"24.5","Tissue RNA - lymph node [nTPM]":"11.7","Tissue RNA - medulla oblongata [nTPM]":"13.3","Tissue RNA - midbrain [nTPM]":"12.0","Tissue RNA - ovary [nTPM]":"35.9","Tissue RNA - pancreas [nTPM]":"29.9","Tissue RNA - parathyroid gland [nTPM]":"22.7","Tissue RNA - pituitary gland [nTPM]":"30.7","Tissue RNA - placenta [nTPM]":"28.4","Tissue RNA - pons [nTPM]":"13.2","Tissue RNA - prostate [nTPM]":"26.9","Tissue RNA - rectum [nTPM]":"17.2","Tissue RNA - retina [nTPM]":"12.5","Tissue RNA - salivary gland [nTPM]":"25.9","Tissue RNA - seminal vesicle [nTPM]":"23.3","Tissue RNA - skeletal muscle [nTPM]":"14.4","Tissue RNA - skin 1 [nTPM]":"35.4","Tissue RNA - small intestine [nTPM]":"20.9","Tissue RNA - smooth muscle [nTPM]":"25.1","Tissue RNA - spinal cord [nTPM]":"11.4","Tissue RNA - spleen [nTPM]":"17.6","Tissue RNA - stomach 1 [nTPM]":"23.2","Tissue RNA - testis [nTPM]":"7.6","Tissue RNA - thalamus [nTPM]":"15.8","Tissue RNA - thymus [nTPM]":"11.3","Tissue RNA - thyroid gland [nTPM]":"26.9","Tissue RNA - tongue [nTPM]":"17.6","Tissue RNA - tonsil [nTPM]":"15.7","Tissue RNA - urinary bladder [nTPM]":"25.2","Tissue RNA - vagina [nTPM]":"28.7","Tissue RNA - white matter [nTPM]":"13.0","Cell RNA - A-431 [nTPM]":"27.4","Cell RNA - A549 [nTPM]":"36.0","Cell RNA - AF22 [nTPM]":"8.9","Cell RNA - AN3-CA [nTPM]":"18.0","Cell RNA - ASC diff [nTPM]":"71.7","Cell RNA - ASC TERT1 [nTPM]":"53.8","Cell RNA - BEWO [nTPM]":"13.3","Cell RNA - BJ [nTPM]":"30.5","Cell RNA - BJ hTERT+ [nTPM]":"36.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.3","Cell RNA - CACO-2 [nTPM]":"5.1","Cell RNA - CAPAN-2 [nTPM]":"39.2","Cell RNA - Daudi [nTPM]":"14.8","Cell RNA - EFO-21 [nTPM]":"20.5","Cell RNA - fHDF\/TERT166 [nTPM]":"42.9","Cell RNA - GAMG [nTPM]":"15.2","Cell RNA - HaCaT [nTPM]":"15.5","Cell RNA - HAP1 [nTPM]":"4.0","Cell RNA - HBEC3-KT [nTPM]":"18.5","Cell RNA - HBF TERT88 [nTPM]":"12.7","Cell RNA - HDLM-2 [nTPM]":"6.4","Cell RNA - HEK 293 [nTPM]":"6.9","Cell RNA - HEL [nTPM]":"16.3","Cell RNA - HeLa [nTPM]":"22.2","Cell RNA - Hep G2 [nTPM]":"8.1","Cell RNA - HHSteC [nTPM]":"23.0","Cell RNA - HL-60 [nTPM]":"3.7","Cell RNA - HMC-1 [nTPM]":"2.5","Cell RNA - HSkMC [nTPM]":"36.2","Cell RNA - hTCEpi [nTPM]":"25.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.7","Cell RNA - hTERT-HME1 [nTPM]":"24.9","Cell RNA - hTERT-RPE1 [nTPM]":"34.5","Cell RNA - HUVEC TERT2 [nTPM]":"39.2","Cell RNA - JURKAT [nTPM]":"7.0","Cell RNA - K-562 [nTPM]":"7.5","Cell RNA - Karpas-707 [nTPM]":"22.1","Cell RNA - LHCN-M2 [nTPM]":"40.4","Cell RNA - MCF7 [nTPM]":"10.0","Cell RNA - MOLT-4 [nTPM]":"14.8","Cell RNA - NB-4 [nTPM]":"7.2","Cell RNA - NTERA-2 [nTPM]":"8.0","Cell RNA - OE19 [nTPM]":"16.3","Cell RNA - PC-3 [nTPM]":"5.4","Cell RNA - REH [nTPM]":"1.6","Cell RNA - RH-30 [nTPM]":"16.1","Cell RNA - RPMI-8226 [nTPM]":"7.7","Cell RNA - RPTEC TERT1 [nTPM]":"36.1","Cell RNA - RT4 [nTPM]":"22.8","Cell RNA - SCLC-21H [nTPM]":"4.7","Cell RNA - SH-SY5Y [nTPM]":"14.0","Cell RNA - SiHa [nTPM]":"39.0","Cell RNA - SK-BR-3 [nTPM]":"12.6","Cell RNA - SK-MEL-30 [nTPM]":"17.4","Cell RNA - SuSa [nTPM]":"19.0","Cell RNA - T-47d [nTPM]":"43.7","Cell RNA - THP-1 [nTPM]":"20.9","Cell RNA - TIME [nTPM]":"46.3","Cell RNA - U-138 MG [nTPM]":"33.2","Cell RNA - U-2 OS [nTPM]":"5.4","Cell RNA - U-2197 [nTPM]":"20.9","Cell RNA - U-251 MG [nTPM]":"12.7","Cell RNA - U-266\/70 [nTPM]":"17.9","Cell RNA - U-266\/84 [nTPM]":"18.2","Cell RNA - U-698 [nTPM]":"6.1","Cell RNA - U-87 MG [nTPM]":"26.8","Cell RNA - U-937 [nTPM]":"6.3","Cell RNA - WM-115 [nTPM]":"20.8","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"8.8","Blood RNA - eosinophil [nTPM]":"9.4","Blood RNA - gdT-cell [nTPM]":"2.7","Blood RNA - intermediate monocyte [nTPM]":"5.4","Blood RNA - MAIT T-cell [nTPM]":"3.0","Blood RNA - memory B-cell [nTPM]":"1.9","Blood RNA - memory CD4 T-cell [nTPM]":"2.3","Blood RNA - memory CD8 T-cell [nTPM]":"2.8","Blood RNA - myeloid DC [nTPM]":"15.8","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"3.2","Blood RNA - NK-cell [nTPM]":"8.8","Blood RNA - non-classical monocyte [nTPM]":"8.6","Blood RNA - plasmacytoid DC [nTPM]":"2.0","Blood RNA - T-reg [nTPM]":"1.7","Blood RNA - total PBMC [nTPM]":"5.0","Brain RNA - amygdala [nTPM]":"13.1","Brain RNA - basal ganglia [nTPM]":"13.0","Brain RNA - cerebellum [nTPM]":"10.6","Brain RNA - cerebral cortex [nTPM]":"13.5","Brain RNA - hippocampal formation [nTPM]":"13.3","Brain RNA - hypothalamus [nTPM]":"17.6","Brain RNA - medulla oblongata [nTPM]":"13.3","Brain RNA - midbrain [nTPM]":"12.0","Brain RNA - pons [nTPM]":"13.2","Brain RNA - spinal cord [nTPM]":"11.4","Brain RNA - thalamus [nTPM]":"15.8","Brain RNA - white matter [nTPM]":"13.0","Single Cell Type RNA - Adipocytes [nTPM]":"39.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.9","Single Cell Type RNA - Astrocytes [nTPM]":"48.0","Single Cell Type RNA - B-cells [nTPM]":"26.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"19.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"50.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"28.6","Single Cell Type RNA - Club cells [nTPM]":"17.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"51.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"50.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"39.2","Single Cell Type RNA - dendritic cells [nTPM]":"30.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"27.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"26.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"42.1","Single Cell Type RNA - Endothelial cells [nTPM]":"37.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"24.1","Single Cell Type RNA - Erythroid cells [nTPM]":"15.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"61.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"28.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"39.4","Single Cell Type RNA - Fibroblasts [nTPM]":"34.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"36.5","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"51.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"49.6","Single Cell Type RNA - Hepatocytes [nTPM]":"23.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"29.2","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"76.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.0","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"34.3","Single Cell Type RNA - Langerhans cells [nTPM]":"58.8","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"35.1","Single Cell Type RNA - Macrophages [nTPM]":"43.3","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"44.0","Single Cell Type RNA - monocytes [nTPM]":"33.5","Single Cell Type RNA - Muller glia cells [nTPM]":"13.5","Single Cell Type RNA - NK-cells [nTPM]":"34.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"50.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"43.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.9","Single Cell Type RNA - Paneth cells [nTPM]":"17.0","Single Cell Type RNA - Peritubular cells [nTPM]":"31.6","Single Cell Type RNA - Plasma cells [nTPM]":"19.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"31.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"28.2","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"3.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"30.1","Single Cell Type RNA - T-cells [nTPM]":"25.0","Single Cell Type RNA - Theca cells [nTPM]":"37.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"21.7","Single Cell Type RNA - Urothelial cells [nTPM]":"17.7"},{"Gene":"HIBCH","Gene synonym":[],"Ensembl":"ENSG00000198130","Gene description":"3-hydroxyisobutyryl-CoA hydrolase","Uniprot":["Q6NVY1"],"Chromosome":"2","Position":"190189735-190344193","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Branched-chain amino acid catabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"230.2","Proximal tubular cells":"376.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036540","HPA036541","HPA067080"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"74000","Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA036540":"AB_10673355","HPA036541":"AB_2675182","HPA067080":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.22e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.04e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-3"},"Tissue RNA - adipose tissue [nTPM]":"34.0","Tissue RNA - adrenal gland [nTPM]":"60.1","Tissue RNA - amygdala [nTPM]":"40.6","Tissue RNA - appendix [nTPM]":"17.4","Tissue RNA - basal ganglia [nTPM]":"49.2","Tissue RNA - bone marrow [nTPM]":"14.5","Tissue RNA - breast [nTPM]":"28.5","Tissue RNA - cerebellum [nTPM]":"40.5","Tissue RNA - cerebral cortex [nTPM]":"60.3","Tissue RNA - cervix [nTPM]":"33.4","Tissue RNA - choroid plexus [nTPM]":"51.0","Tissue RNA - colon [nTPM]":"37.5","Tissue RNA - duodenum [nTPM]":"55.9","Tissue RNA - endometrium 1 [nTPM]":"28.1","Tissue RNA - epididymis [nTPM]":"29.1","Tissue RNA - esophagus [nTPM]":"34.9","Tissue RNA - fallopian tube [nTPM]":"22.5","Tissue RNA - gallbladder [nTPM]":"22.3","Tissue RNA - heart muscle [nTPM]":"28.7","Tissue RNA - hippocampal formation [nTPM]":"40.7","Tissue RNA - hypothalamus [nTPM]":"47.7","Tissue RNA - kidney [nTPM]":"142.2","Tissue RNA - liver [nTPM]":"129.0","Tissue RNA - lung [nTPM]":"13.9","Tissue RNA - lymph node [nTPM]":"20.5","Tissue RNA - medulla oblongata [nTPM]":"43.9","Tissue RNA - midbrain [nTPM]":"43.1","Tissue RNA - ovary [nTPM]":"18.6","Tissue RNA - pancreas [nTPM]":"27.2","Tissue RNA - parathyroid gland [nTPM]":"58.2","Tissue RNA - pituitary gland [nTPM]":"19.1","Tissue RNA - placenta [nTPM]":"18.6","Tissue RNA - pons [nTPM]":"44.9","Tissue RNA - prostate [nTPM]":"25.5","Tissue RNA - rectum [nTPM]":"40.9","Tissue RNA - retina [nTPM]":"38.4","Tissue RNA - salivary gland [nTPM]":"20.9","Tissue RNA - seminal vesicle [nTPM]":"23.2","Tissue RNA - skeletal muscle [nTPM]":"49.2","Tissue RNA - skin 1 [nTPM]":"58.7","Tissue RNA - small intestine [nTPM]":"33.9","Tissue RNA - smooth muscle [nTPM]":"18.3","Tissue RNA - spinal cord [nTPM]":"45.0","Tissue RNA - spleen [nTPM]":"17.8","Tissue RNA - stomach 1 [nTPM]":"25.6","Tissue RNA - testis [nTPM]":"21.7","Tissue RNA - thalamus [nTPM]":"43.3","Tissue RNA - thymus [nTPM]":"16.8","Tissue RNA - thyroid gland [nTPM]":"31.7","Tissue RNA - tongue [nTPM]":"38.5","Tissue RNA - tonsil [nTPM]":"21.9","Tissue RNA - urinary bladder [nTPM]":"23.7","Tissue RNA - vagina [nTPM]":"26.6","Tissue RNA - white matter [nTPM]":"72.6","Cell RNA - A-431 [nTPM]":"23.5","Cell RNA - A549 [nTPM]":"16.1","Cell RNA - AF22 [nTPM]":"37.0","Cell RNA - AN3-CA [nTPM]":"23.8","Cell RNA - ASC diff [nTPM]":"29.9","Cell RNA - ASC TERT1 [nTPM]":"27.6","Cell RNA - BEWO [nTPM]":"16.9","Cell RNA - BJ [nTPM]":"23.1","Cell RNA - BJ hTERT+ [nTPM]":"11.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"22.1","Cell RNA - CACO-2 [nTPM]":"46.8","Cell RNA - CAPAN-2 [nTPM]":"20.2","Cell RNA - Daudi [nTPM]":"33.3","Cell RNA - EFO-21 [nTPM]":"36.1","Cell RNA - fHDF\/TERT166 [nTPM]":"18.1","Cell RNA - GAMG [nTPM]":"17.0","Cell RNA - HaCaT [nTPM]":"44.4","Cell RNA - HAP1 [nTPM]":"33.2","Cell RNA - HBEC3-KT [nTPM]":"30.7","Cell RNA - HBF TERT88 [nTPM]":"29.5","Cell RNA - HDLM-2 [nTPM]":"47.0","Cell RNA - HEK 293 [nTPM]":"25.1","Cell RNA - HEL [nTPM]":"44.5","Cell RNA - HeLa [nTPM]":"37.7","Cell RNA - Hep G2 [nTPM]":"41.4","Cell RNA - HHSteC [nTPM]":"10.7","Cell RNA - HL-60 [nTPM]":"31.8","Cell RNA - HMC-1 [nTPM]":"16.7","Cell RNA - HSkMC [nTPM]":"19.8","Cell RNA - hTCEpi [nTPM]":"17.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"24.3","Cell RNA - hTERT-HME1 [nTPM]":"4.8","Cell RNA - hTERT-RPE1 [nTPM]":"32.3","Cell RNA - HUVEC TERT2 [nTPM]":"31.6","Cell RNA - JURKAT [nTPM]":"30.4","Cell RNA - K-562 [nTPM]":"55.2","Cell RNA - Karpas-707 [nTPM]":"30.3","Cell RNA - LHCN-M2 [nTPM]":"20.8","Cell RNA - MCF7 [nTPM]":"18.2","Cell RNA - MOLT-4 [nTPM]":"34.3","Cell RNA - NB-4 [nTPM]":"33.6","Cell RNA - NTERA-2 [nTPM]":"11.1","Cell RNA - OE19 [nTPM]":"30.2","Cell RNA - PC-3 [nTPM]":"30.2","Cell RNA - REH [nTPM]":"42.4","Cell RNA - RH-30 [nTPM]":"24.8","Cell RNA - RPMI-8226 [nTPM]":"83.8","Cell RNA - RPTEC TERT1 [nTPM]":"43.8","Cell RNA - RT4 [nTPM]":"68.4","Cell RNA - SCLC-21H [nTPM]":"27.9","Cell RNA - SH-SY5Y [nTPM]":"24.0","Cell RNA - SiHa [nTPM]":"18.0","Cell RNA - SK-BR-3 [nTPM]":"27.2","Cell RNA - SK-MEL-30 [nTPM]":"66.8","Cell RNA - SuSa [nTPM]":"47.2","Cell RNA - T-47d [nTPM]":"32.0","Cell RNA - THP-1 [nTPM]":"21.3","Cell RNA - TIME [nTPM]":"26.5","Cell RNA - U-138 MG [nTPM]":"22.8","Cell RNA - U-2 OS [nTPM]":"20.8","Cell RNA - U-2197 [nTPM]":"16.1","Cell RNA - U-251 MG [nTPM]":"15.8","Cell RNA - U-266\/70 [nTPM]":"18.7","Cell RNA - U-266\/84 [nTPM]":"45.2","Cell RNA - U-698 [nTPM]":"30.9","Cell RNA - U-87 MG [nTPM]":"20.7","Cell RNA - U-937 [nTPM]":"27.4","Cell RNA - WM-115 [nTPM]":"18.6","Blood RNA - basophil [nTPM]":"27.8","Blood RNA - classical monocyte [nTPM]":"11.9","Blood RNA - eosinophil [nTPM]":"26.4","Blood RNA - gdT-cell [nTPM]":"19.5","Blood RNA - intermediate monocyte [nTPM]":"14.2","Blood RNA - MAIT T-cell [nTPM]":"21.3","Blood RNA - memory B-cell [nTPM]":"43.5","Blood RNA - memory CD4 T-cell [nTPM]":"21.8","Blood RNA - memory CD8 T-cell [nTPM]":"21.0","Blood RNA - myeloid DC [nTPM]":"20.9","Blood RNA - naive B-cell [nTPM]":"34.7","Blood RNA - naive CD4 T-cell [nTPM]":"22.9","Blood RNA - naive CD8 T-cell [nTPM]":"29.6","Blood RNA - neutrophil [nTPM]":"6.0","Blood RNA - NK-cell [nTPM]":"32.0","Blood RNA - non-classical monocyte [nTPM]":"11.3","Blood RNA - plasmacytoid DC [nTPM]":"26.7","Blood RNA - T-reg [nTPM]":"37.0","Blood RNA - total PBMC [nTPM]":"12.7","Brain RNA - amygdala [nTPM]":"40.6","Brain RNA - basal ganglia [nTPM]":"49.2","Brain RNA - cerebellum [nTPM]":"40.5","Brain RNA - cerebral cortex [nTPM]":"60.3","Brain RNA - hippocampal formation [nTPM]":"40.7","Brain RNA - hypothalamus [nTPM]":"47.7","Brain RNA - medulla oblongata [nTPM]":"43.9","Brain RNA - midbrain [nTPM]":"43.1","Brain RNA - pons [nTPM]":"44.9","Brain RNA - spinal cord [nTPM]":"45.0","Brain RNA - thalamus [nTPM]":"43.3","Brain RNA - white matter [nTPM]":"72.6","Single Cell Type RNA - Adipocytes [nTPM]":"23.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.8","Single Cell Type RNA - Astrocytes [nTPM]":"129.3","Single Cell Type RNA - B-cells [nTPM]":"29.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"56.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"131.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"74.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"34.1","Single Cell Type RNA - Bipolar cells [nTPM]":"35.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"39.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"28.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"42.9","Single Cell Type RNA - Club cells [nTPM]":"51.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"102.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"53.6","Single Cell Type RNA - dendritic cells [nTPM]":"18.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"53.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"115.4","Single Cell Type RNA - Ductal cells [nTPM]":"27.4","Single Cell Type RNA - Early spermatids [nTPM]":"230.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"48.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.4","Single Cell Type RNA - Endothelial cells [nTPM]":"33.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"37.8","Single Cell Type RNA - Erythroid cells [nTPM]":"13.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"46.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"29.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"22.3","Single Cell Type RNA - Fibroblasts [nTPM]":"27.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"29.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"39.3","Single Cell Type RNA - granulocytes [nTPM]":"10.2","Single Cell Type RNA - Granulosa cells [nTPM]":"41.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"89.3","Single Cell Type RNA - Hepatocytes [nTPM]":"117.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"35.3","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"51.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.4","Single Cell Type RNA - Ionocytes [nTPM]":"71.2","Single Cell Type RNA - Kupffer cells [nTPM]":"15.7","Single Cell Type RNA - Langerhans cells [nTPM]":"11.7","Single Cell Type RNA - Late spermatids [nTPM]":"62.9","Single Cell Type RNA - Leydig cells [nTPM]":"34.8","Single Cell Type RNA - Macrophages [nTPM]":"15.9","Single Cell Type RNA - Melanocytes [nTPM]":"46.2","Single Cell Type RNA - Microglial cells [nTPM]":"52.5","Single Cell Type RNA - monocytes [nTPM]":"14.1","Single Cell Type RNA - Muller glia cells [nTPM]":"35.5","Single Cell Type RNA - NK-cells [nTPM]":"39.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"104.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"141.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.6","Single Cell Type RNA - Paneth cells [nTPM]":"26.6","Single Cell Type RNA - Peritubular cells [nTPM]":"45.5","Single Cell Type RNA - Plasma cells [nTPM]":"23.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"27.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"32.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"376.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"47.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"50.5","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"29.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.2","Single Cell Type RNA - Spermatocytes [nTPM]":"18.0","Single Cell Type RNA - Spermatogonia [nTPM]":"29.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"45.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"40.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.0","Single Cell Type RNA - T-cells [nTPM]":"30.7","Single Cell Type RNA - Theca cells [nTPM]":"61.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"62.7","Single Cell Type RNA - Urothelial cells [nTPM]":"67.8"},{"Gene":"HK1","Gene synonym":[],"Ensembl":"ENSG00000156515","Gene description":"Hexokinase 1","Uniprot":["P19367"],"Chromosome":"10","Position":"69269984-69401884","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Glycolysis","Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Allosteric enzyme","Kinase","Transferase"],"Disease involvement":["Cancer-related genes","Charcot-Marie-Tooth disease","Disease variant","Mental retardation","Neurodegeneration","Neuropathy","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"374.0","Horizontal cells":"304.5","Late spermatids":"1034.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007043","HPA007044","CAB010052"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"560000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB010052":"AB_627721","HPA007043":"AB_1850652","HPA007044":"AB_1079049"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.39e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Tissue RNA - adipose tissue [nTPM]":"47.0","Tissue RNA - adrenal gland [nTPM]":"24.4","Tissue RNA - amygdala [nTPM]":"61.0","Tissue RNA - appendix [nTPM]":"45.0","Tissue RNA - basal ganglia [nTPM]":"65.7","Tissue RNA - bone marrow [nTPM]":"60.3","Tissue RNA - breast [nTPM]":"40.6","Tissue RNA - cerebellum [nTPM]":"58.0","Tissue RNA - cerebral cortex [nTPM]":"76.6","Tissue RNA - cervix [nTPM]":"54.7","Tissue RNA - choroid plexus [nTPM]":"64.2","Tissue RNA - colon [nTPM]":"60.1","Tissue RNA - duodenum [nTPM]":"13.1","Tissue RNA - endometrium 1 [nTPM]":"41.3","Tissue RNA - epididymis [nTPM]":"11.2","Tissue RNA - esophagus [nTPM]":"129.9","Tissue RNA - fallopian tube [nTPM]":"37.0","Tissue RNA - gallbladder [nTPM]":"25.7","Tissue RNA - heart muscle [nTPM]":"150.8","Tissue RNA - hippocampal formation [nTPM]":"69.1","Tissue RNA - hypothalamus [nTPM]":"62.7","Tissue RNA - kidney [nTPM]":"49.2","Tissue RNA - liver [nTPM]":"8.5","Tissue RNA - lung [nTPM]":"48.1","Tissue RNA - lymph node [nTPM]":"34.1","Tissue RNA - medulla oblongata [nTPM]":"56.7","Tissue RNA - midbrain [nTPM]":"59.8","Tissue RNA - ovary [nTPM]":"19.9","Tissue RNA - pancreas [nTPM]":"12.3","Tissue RNA - parathyroid gland [nTPM]":"25.0","Tissue RNA - pituitary gland [nTPM]":"44.9","Tissue RNA - placenta [nTPM]":"49.3","Tissue RNA - pons [nTPM]":"71.1","Tissue RNA - prostate [nTPM]":"52.9","Tissue RNA - rectum [nTPM]":"31.9","Tissue RNA - retina [nTPM]":"147.6","Tissue RNA - salivary gland [nTPM]":"67.1","Tissue RNA - seminal vesicle [nTPM]":"53.1","Tissue RNA - skeletal muscle [nTPM]":"193.5","Tissue RNA - skin 1 [nTPM]":"102.6","Tissue RNA - small intestine [nTPM]":"29.2","Tissue RNA - smooth muscle [nTPM]":"49.8","Tissue RNA - spinal cord [nTPM]":"40.0","Tissue RNA - spleen [nTPM]":"40.3","Tissue RNA - stomach 1 [nTPM]":"61.6","Tissue RNA - testis [nTPM]":"77.2","Tissue RNA - thalamus [nTPM]":"53.5","Tissue RNA - thymus [nTPM]":"44.9","Tissue RNA - thyroid gland [nTPM]":"71.0","Tissue RNA - tongue [nTPM]":"146.7","Tissue RNA - tonsil [nTPM]":"47.6","Tissue RNA - urinary bladder [nTPM]":"74.3","Tissue RNA - vagina [nTPM]":"80.9","Tissue RNA - white matter [nTPM]":"54.1","Cell RNA - A-431 [nTPM]":"101.6","Cell RNA - A549 [nTPM]":"56.6","Cell RNA - AF22 [nTPM]":"74.2","Cell RNA - AN3-CA [nTPM]":"71.1","Cell RNA - ASC diff [nTPM]":"81.0","Cell RNA - ASC TERT1 [nTPM]":"60.4","Cell RNA - BEWO [nTPM]":"47.1","Cell RNA - BJ [nTPM]":"98.3","Cell RNA - BJ hTERT+ [nTPM]":"256.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"128.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"138.0","Cell RNA - CACO-2 [nTPM]":"16.3","Cell RNA - CAPAN-2 [nTPM]":"11.0","Cell RNA - Daudi [nTPM]":"7.3","Cell RNA - EFO-21 [nTPM]":"75.8","Cell RNA - fHDF\/TERT166 [nTPM]":"165.9","Cell RNA - GAMG [nTPM]":"92.9","Cell RNA - HaCaT [nTPM]":"86.2","Cell RNA - HAP1 [nTPM]":"69.9","Cell RNA - HBEC3-KT [nTPM]":"220.0","Cell RNA - HBF TERT88 [nTPM]":"122.0","Cell RNA - HDLM-2 [nTPM]":"67.5","Cell RNA - HEK 293 [nTPM]":"54.5","Cell RNA - HEL [nTPM]":"250.0","Cell RNA - HeLa [nTPM]":"58.3","Cell RNA - Hep G2 [nTPM]":"1.1","Cell RNA - HHSteC [nTPM]":"91.7","Cell RNA - HL-60 [nTPM]":"5.1","Cell RNA - HMC-1 [nTPM]":"181.2","Cell RNA - HSkMC [nTPM]":"91.5","Cell RNA - hTCEpi [nTPM]":"125.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"184.5","Cell RNA - hTERT-HME1 [nTPM]":"407.6","Cell RNA - hTERT-RPE1 [nTPM]":"160.8","Cell RNA - HUVEC TERT2 [nTPM]":"135.4","Cell RNA - JURKAT [nTPM]":"36.8","Cell RNA - K-562 [nTPM]":"424.5","Cell RNA - Karpas-707 [nTPM]":"51.3","Cell RNA - LHCN-M2 [nTPM]":"178.7","Cell RNA - MCF7 [nTPM]":"167.7","Cell RNA - MOLT-4 [nTPM]":"29.7","Cell RNA - NB-4 [nTPM]":"13.1","Cell RNA - NTERA-2 [nTPM]":"113.8","Cell RNA - OE19 [nTPM]":"51.7","Cell RNA - PC-3 [nTPM]":"247.0","Cell RNA - REH [nTPM]":"44.8","Cell RNA - RH-30 [nTPM]":"45.0","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"88.7","Cell RNA - RT4 [nTPM]":"117.4","Cell RNA - SCLC-21H [nTPM]":"75.7","Cell RNA - SH-SY5Y [nTPM]":"88.7","Cell RNA - SiHa [nTPM]":"112.6","Cell RNA - SK-BR-3 [nTPM]":"215.4","Cell RNA - SK-MEL-30 [nTPM]":"65.2","Cell RNA - SuSa [nTPM]":"104.3","Cell RNA - T-47d [nTPM]":"117.7","Cell RNA - THP-1 [nTPM]":"16.5","Cell RNA - TIME [nTPM]":"140.4","Cell RNA - U-138 MG [nTPM]":"190.5","Cell RNA - U-2 OS [nTPM]":"86.4","Cell RNA - U-2197 [nTPM]":"106.5","Cell RNA - U-251 MG [nTPM]":"139.6","Cell RNA - U-266\/70 [nTPM]":"61.1","Cell RNA - U-266\/84 [nTPM]":"42.8","Cell RNA - U-698 [nTPM]":"17.4","Cell RNA - U-87 MG [nTPM]":"247.3","Cell RNA - U-937 [nTPM]":"130.4","Cell RNA - WM-115 [nTPM]":"56.1","Blood RNA - basophil [nTPM]":"68.7","Blood RNA - classical monocyte [nTPM]":"88.8","Blood RNA - eosinophil [nTPM]":"44.6","Blood RNA - gdT-cell [nTPM]":"41.5","Blood RNA - intermediate monocyte [nTPM]":"125.2","Blood RNA - MAIT T-cell [nTPM]":"69.0","Blood RNA - memory B-cell [nTPM]":"33.5","Blood RNA - memory CD4 T-cell [nTPM]":"47.9","Blood RNA - memory CD8 T-cell [nTPM]":"47.6","Blood RNA - myeloid DC [nTPM]":"81.0","Blood RNA - naive B-cell [nTPM]":"19.9","Blood RNA - naive CD4 T-cell [nTPM]":"41.7","Blood RNA - naive CD8 T-cell [nTPM]":"33.9","Blood RNA - neutrophil [nTPM]":"20.9","Blood RNA - NK-cell [nTPM]":"31.2","Blood RNA - non-classical monocyte [nTPM]":"135.4","Blood RNA - plasmacytoid DC [nTPM]":"9.1","Blood RNA - T-reg [nTPM]":"58.1","Blood RNA - total PBMC [nTPM]":"110.4","Brain RNA - amygdala [nTPM]":"61.0","Brain RNA - basal ganglia [nTPM]":"65.7","Brain RNA - cerebellum [nTPM]":"58.0","Brain RNA - cerebral cortex [nTPM]":"76.6","Brain RNA - hippocampal formation [nTPM]":"69.1","Brain RNA - hypothalamus [nTPM]":"62.7","Brain RNA - medulla oblongata [nTPM]":"56.7","Brain RNA - midbrain [nTPM]":"59.8","Brain RNA - pons [nTPM]":"71.1","Brain RNA - spinal cord [nTPM]":"40.0","Brain RNA - thalamus [nTPM]":"53.5","Brain RNA - white matter [nTPM]":"54.1","Single Cell Type RNA - Adipocytes [nTPM]":"26.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"32.4","Single Cell Type RNA - Astrocytes [nTPM]":"38.2","Single Cell Type RNA - B-cells [nTPM]":"26.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"48.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"50.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"37.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"43.9","Single Cell Type RNA - Bipolar cells [nTPM]":"83.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"33.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"130.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"34.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"54.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"70.6","Single Cell Type RNA - dendritic cells [nTPM]":"14.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"30.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"28.6","Single Cell Type RNA - Early spermatids [nTPM]":"374.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"32.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"28.0","Single Cell Type RNA - Endothelial cells [nTPM]":"37.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.7","Single Cell Type RNA - Erythroid cells [nTPM]":"104.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"53.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"93.3","Single Cell Type RNA - Fibroblasts [nTPM]":"30.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"41.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"34.5","Single Cell Type RNA - granulocytes [nTPM]":"23.4","Single Cell Type RNA - Granulosa cells [nTPM]":"72.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.7","Single Cell Type RNA - Hepatocytes [nTPM]":"1.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"49.4","Single Cell Type RNA - Horizontal cells [nTPM]":"304.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"49.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.7","Single Cell Type RNA - Ionocytes [nTPM]":"44.7","Single Cell Type RNA - Kupffer cells [nTPM]":"41.7","Single Cell Type RNA - Langerhans cells [nTPM]":"21.9","Single Cell Type RNA - Late spermatids [nTPM]":"1034.1","Single Cell Type RNA - Leydig cells [nTPM]":"15.2","Single Cell Type RNA - Macrophages [nTPM]":"51.3","Single Cell Type RNA - Melanocytes [nTPM]":"37.4","Single Cell Type RNA - Microglial cells [nTPM]":"29.0","Single Cell Type RNA - monocytes [nTPM]":"35.3","Single Cell Type RNA - Muller glia cells [nTPM]":"32.9","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"54.6","Single Cell Type RNA - Paneth cells [nTPM]":"11.1","Single Cell Type RNA - Peritubular cells [nTPM]":"18.4","Single Cell Type RNA - Plasma cells [nTPM]":"19.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"29.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"30.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"95.5","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"43.1","Single Cell Type RNA - Spermatocytes [nTPM]":"5.3","Single Cell Type RNA - Spermatogonia [nTPM]":"6.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"86.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"51.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"118.9","Single Cell Type RNA - T-cells [nTPM]":"30.5","Single Cell Type RNA - Theca cells [nTPM]":"28.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.3","Single Cell Type RNA - Urothelial cells [nTPM]":"43.5"},{"Gene":"HLA-A","Gene synonym":[],"Ensembl":"ENSG00000206503","Gene description":"Major histocompatibility complex, class I, A","Uniprot":["P04439"],"Chromosome":"6","Position":"29941260-29945884","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"3747.8","Proximal enterocytes":"5267.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"1363.9","fHDF\/TERT166":"360.3","HBEC3-KT":"366.7","RPMI-8226":"372.1","U-266\/70":"344.6"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB078470"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000000","Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB078470":"AB_10985125"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.59e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.47e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Tissue RNA - adipose tissue [nTPM]":"635.4","Tissue RNA - adrenal gland [nTPM]":"714.2","Tissue RNA - amygdala [nTPM]":"15.0","Tissue RNA - appendix [nTPM]":"34.8","Tissue RNA - basal ganglia [nTPM]":"15.5","Tissue RNA - bone marrow [nTPM]":"137.7","Tissue RNA - breast [nTPM]":"566.7","Tissue RNA - cerebellum [nTPM]":"14.7","Tissue RNA - cerebral cortex [nTPM]":"36.5","Tissue RNA - cervix [nTPM]":"504.9","Tissue RNA - choroid plexus [nTPM]":"18.0","Tissue RNA - colon [nTPM]":"737.5","Tissue RNA - duodenum [nTPM]":"278.3","Tissue RNA - endometrium 1 [nTPM]":"476.1","Tissue RNA - epididymis [nTPM]":"181.1","Tissue RNA - esophagus [nTPM]":"366.8","Tissue RNA - fallopian tube [nTPM]":"390.3","Tissue RNA - gallbladder [nTPM]":"239.9","Tissue RNA - heart muscle [nTPM]":"473.4","Tissue RNA - hippocampal formation [nTPM]":"14.6","Tissue RNA - hypothalamus [nTPM]":"17.0","Tissue RNA - kidney [nTPM]":"687.0","Tissue RNA - liver [nTPM]":"392.0","Tissue RNA - lung [nTPM]":"1007.3","Tissue RNA - lymph node [nTPM]":"132.0","Tissue RNA - medulla oblongata [nTPM]":"19.1","Tissue RNA - midbrain [nTPM]":"15.8","Tissue RNA - ovary [nTPM]":"338.8","Tissue RNA - pancreas [nTPM]":"200.0","Tissue RNA - parathyroid gland [nTPM]":"18.5","Tissue RNA - pituitary gland [nTPM]":"406.5","Tissue RNA - placenta [nTPM]":"52.1","Tissue RNA - pons [nTPM]":"16.5","Tissue RNA - prostate [nTPM]":"370.9","Tissue RNA - rectum [nTPM]":"94.6","Tissue RNA - retina [nTPM]":"9.9","Tissue RNA - salivary gland [nTPM]":"364.1","Tissue RNA - seminal vesicle [nTPM]":"1.2","Tissue RNA - skeletal muscle [nTPM]":"246.5","Tissue RNA - skin 1 [nTPM]":"673.3","Tissue RNA - small intestine [nTPM]":"959.1","Tissue RNA - smooth muscle [nTPM]":"14.5","Tissue RNA - spinal cord [nTPM]":"16.8","Tissue RNA - spleen [nTPM]":"1413.1","Tissue RNA - stomach 1 [nTPM]":"442.2","Tissue RNA - testis [nTPM]":"132.6","Tissue RNA - thalamus [nTPM]":"18.0","Tissue RNA - thymus [nTPM]":"138.9","Tissue RNA - thyroid gland [nTPM]":"531.9","Tissue RNA - tongue [nTPM]":"14.5","Tissue RNA - tonsil [nTPM]":"178.3","Tissue RNA - urinary bladder [nTPM]":"412.3","Tissue RNA - vagina [nTPM]":"466.8","Tissue RNA - white matter [nTPM]":"18.3","Cell RNA - A-431 [nTPM]":"1363.9","Cell RNA - A549 [nTPM]":"35.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"205.9","Cell RNA - ASC TERT1 [nTPM]":"193.7","Cell RNA - BEWO [nTPM]":"1.4","Cell RNA - BJ [nTPM]":"1.4","Cell RNA - BJ hTERT+ [nTPM]":"2.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.3","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"4.0","Cell RNA - EFO-21 [nTPM]":"0.6","Cell RNA - fHDF\/TERT166 [nTPM]":"360.3","Cell RNA - GAMG [nTPM]":"179.1","Cell RNA - HaCaT [nTPM]":"31.2","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"366.7","Cell RNA - HBF TERT88 [nTPM]":"0.5","Cell RNA - HDLM-2 [nTPM]":"3.1","Cell RNA - HEK 293 [nTPM]":"13.5","Cell RNA - HEL [nTPM]":"237.5","Cell RNA - HeLa [nTPM]":"9.5","Cell RNA - Hep G2 [nTPM]":"7.4","Cell RNA - HHSteC [nTPM]":"11.2","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"14.4","Cell RNA - HSkMC [nTPM]":"2.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.5","Cell RNA - hTERT-HME1 [nTPM]":"1.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"177.8","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"1.4","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"1.1","Cell RNA - NB-4 [nTPM]":"24.3","Cell RNA - NTERA-2 [nTPM]":"2.9","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"4.1","Cell RNA - REH [nTPM]":"27.5","Cell RNA - RH-30 [nTPM]":"2.5","Cell RNA - RPMI-8226 [nTPM]":"372.1","Cell RNA - RPTEC TERT1 [nTPM]":"246.7","Cell RNA - RT4 [nTPM]":"276.5","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"12.4","Cell RNA - SiHa [nTPM]":"29.3","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"11.8","Cell RNA - SuSa [nTPM]":"82.8","Cell RNA - T-47d [nTPM]":"1.6","Cell RNA - THP-1 [nTPM]":"30.4","Cell RNA - TIME [nTPM]":"5.8","Cell RNA - U-138 MG [nTPM]":"18.7","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"5.8","Cell RNA - U-251 MG [nTPM]":"4.0","Cell RNA - U-266\/70 [nTPM]":"344.6","Cell RNA - U-266\/84 [nTPM]":"92.6","Cell RNA - U-698 [nTPM]":"77.7","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"199.9","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"321.6","Blood RNA - classical monocyte [nTPM]":"119.0","Blood RNA - eosinophil [nTPM]":"182.7","Blood RNA - gdT-cell [nTPM]":"164.7","Blood RNA - intermediate monocyte [nTPM]":"95.5","Blood RNA - MAIT T-cell [nTPM]":"134.8","Blood RNA - memory B-cell [nTPM]":"96.9","Blood RNA - memory CD4 T-cell [nTPM]":"125.4","Blood RNA - memory CD8 T-cell [nTPM]":"146.3","Blood RNA - myeloid DC [nTPM]":"18.6","Blood RNA - naive B-cell [nTPM]":"64.3","Blood RNA - naive CD4 T-cell [nTPM]":"86.5","Blood RNA - naive CD8 T-cell [nTPM]":"119.2","Blood RNA - neutrophil [nTPM]":"248.7","Blood RNA - NK-cell [nTPM]":"133.1","Blood RNA - non-classical monocyte [nTPM]":"109.6","Blood RNA - plasmacytoid DC [nTPM]":"54.6","Blood RNA - T-reg [nTPM]":"222.2","Blood RNA - total PBMC [nTPM]":"191.9","Brain RNA - amygdala [nTPM]":"15.0","Brain RNA - basal ganglia [nTPM]":"15.5","Brain RNA - cerebellum [nTPM]":"14.7","Brain RNA - cerebral cortex [nTPM]":"36.5","Brain RNA - hippocampal formation [nTPM]":"14.6","Brain RNA - hypothalamus [nTPM]":"17.0","Brain RNA - medulla oblongata [nTPM]":"19.1","Brain RNA - midbrain [nTPM]":"15.8","Brain RNA - pons [nTPM]":"16.5","Brain RNA - spinal cord [nTPM]":"16.8","Brain RNA - thalamus [nTPM]":"18.0","Brain RNA - white matter [nTPM]":"18.3","Single Cell Type RNA - Adipocytes [nTPM]":"1622.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"371.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"478.6","Single Cell Type RNA - Astrocytes [nTPM]":"22.9","Single Cell Type RNA - B-cells [nTPM]":"1316.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"856.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"886.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1417.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"228.8","Single Cell Type RNA - Bipolar cells [nTPM]":"30.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"289.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"188.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"147.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"936.5","Single Cell Type RNA - Club cells [nTPM]":"952.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"503.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.3","Single Cell Type RNA - dendritic cells [nTPM]":"1879.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"2631.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"88.0","Single Cell Type RNA - Ductal cells [nTPM]":"3747.8","Single Cell Type RNA - Early spermatids [nTPM]":"52.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"239.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"374.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1717.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"955.2","Single Cell Type RNA - Erythroid cells [nTPM]":"499.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1310.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.5","Single Cell Type RNA - Fibroblasts [nTPM]":"743.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"853.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"556.2","Single Cell Type RNA - granulocytes [nTPM]":"603.0","Single Cell Type RNA - Granulosa cells [nTPM]":"253.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1266.2","Single Cell Type RNA - Hepatocytes [nTPM]":"276.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"1840.9","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"19.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1755.3","Single Cell Type RNA - Ionocytes [nTPM]":"1265.4","Single Cell Type RNA - Kupffer cells [nTPM]":"1575.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1124.0","Single Cell Type RNA - Late spermatids [nTPM]":"95.6","Single Cell Type RNA - Leydig cells [nTPM]":"704.6","Single Cell Type RNA - Macrophages [nTPM]":"1419.1","Single Cell Type RNA - Melanocytes [nTPM]":"635.0","Single Cell Type RNA - Microglial cells [nTPM]":"67.5","Single Cell Type RNA - monocytes [nTPM]":"3258.0","Single Cell Type RNA - Muller glia cells [nTPM]":"170.4","Single Cell Type RNA - NK-cells [nTPM]":"3201.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"49.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1802.9","Single Cell Type RNA - Paneth cells [nTPM]":"2452.4","Single Cell Type RNA - Peritubular cells [nTPM]":"484.1","Single Cell Type RNA - Plasma cells [nTPM]":"1110.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1026.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5267.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"294.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"609.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.4","Single Cell Type RNA - Sertoli cells [nTPM]":"558.8","Single Cell Type RNA - Skeletal myocytes [nTPM]":"397.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"579.2","Single Cell Type RNA - Spermatocytes [nTPM]":"197.4","Single Cell Type RNA - Spermatogonia [nTPM]":"23.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"216.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"947.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"31.7","Single Cell Type RNA - T-cells [nTPM]":"2234.9","Single Cell Type RNA - Theca cells [nTPM]":"1021.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1225.4","Single Cell Type RNA - Urothelial cells [nTPM]":"1262.8"},{"Gene":"HLCS","Gene synonym":["HCS"],"Ensembl":"ENSG00000159267","Gene description":"Holocarboxylase synthetase","Uniprot":["P50747"],"Chromosome":"21","Position":"36748626-36990236","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Ligase","Multifunctional enzyme"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"86.2","Inhibitory neurons":"99.7","Oligodendrocyte precursor cells":"79.9","Oligodendrocytes":"80.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017379"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA017379":"AB_1850768"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.72e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.0","Tissue RNA - adrenal gland [nTPM]":"5.1","Tissue RNA - amygdala [nTPM]":"4.9","Tissue RNA - appendix [nTPM]":"4.2","Tissue RNA - basal ganglia [nTPM]":"5.5","Tissue RNA - bone marrow [nTPM]":"3.3","Tissue RNA - breast [nTPM]":"7.4","Tissue RNA - cerebellum [nTPM]":"9.1","Tissue RNA - cerebral cortex [nTPM]":"5.8","Tissue RNA - cervix [nTPM]":"5.1","Tissue RNA - choroid plexus [nTPM]":"9.4","Tissue RNA - colon [nTPM]":"4.7","Tissue RNA - duodenum [nTPM]":"4.2","Tissue RNA - endometrium 1 [nTPM]":"4.0","Tissue RNA - epididymis [nTPM]":"7.0","Tissue RNA - esophagus [nTPM]":"6.1","Tissue RNA - fallopian tube [nTPM]":"5.3","Tissue RNA - gallbladder [nTPM]":"4.2","Tissue RNA - heart muscle [nTPM]":"3.7","Tissue RNA - hippocampal formation [nTPM]":"6.3","Tissue RNA - hypothalamus [nTPM]":"5.4","Tissue RNA - kidney [nTPM]":"6.4","Tissue RNA - liver [nTPM]":"10.6","Tissue RNA - lung [nTPM]":"4.9","Tissue RNA - lymph node [nTPM]":"3.7","Tissue RNA - medulla oblongata [nTPM]":"5.9","Tissue RNA - midbrain [nTPM]":"4.6","Tissue RNA - ovary [nTPM]":"3.8","Tissue RNA - pancreas [nTPM]":"7.6","Tissue RNA - parathyroid gland [nTPM]":"10.6","Tissue RNA - pituitary gland [nTPM]":"8.8","Tissue RNA - placenta [nTPM]":"4.1","Tissue RNA - pons [nTPM]":"6.3","Tissue RNA - prostate [nTPM]":"8.9","Tissue RNA - rectum [nTPM]":"4.4","Tissue RNA - retina [nTPM]":"6.1","Tissue RNA - salivary gland [nTPM]":"8.5","Tissue RNA - seminal vesicle [nTPM]":"6.6","Tissue RNA - skeletal muscle [nTPM]":"13.3","Tissue RNA - skin 1 [nTPM]":"2.8","Tissue RNA - small intestine [nTPM]":"4.9","Tissue RNA - smooth muscle [nTPM]":"4.5","Tissue RNA - spinal cord [nTPM]":"4.1","Tissue RNA - spleen [nTPM]":"3.1","Tissue RNA - stomach 1 [nTPM]":"5.7","Tissue RNA - testis [nTPM]":"5.7","Tissue RNA - thalamus [nTPM]":"5.4","Tissue RNA - thymus [nTPM]":"3.3","Tissue RNA - thyroid gland [nTPM]":"10.7","Tissue RNA - tongue [nTPM]":"6.2","Tissue RNA - tonsil [nTPM]":"4.3","Tissue RNA - urinary bladder [nTPM]":"5.4","Tissue RNA - vagina [nTPM]":"2.8","Tissue RNA - white matter [nTPM]":"5.5","Cell RNA - A-431 [nTPM]":"23.8","Cell RNA - A549 [nTPM]":"10.4","Cell RNA - AF22 [nTPM]":"13.0","Cell RNA - AN3-CA [nTPM]":"9.6","Cell RNA - ASC diff [nTPM]":"14.8","Cell RNA - ASC TERT1 [nTPM]":"13.7","Cell RNA - BEWO [nTPM]":"13.3","Cell RNA - BJ [nTPM]":"13.0","Cell RNA - BJ hTERT+ [nTPM]":"12.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.0","Cell RNA - CACO-2 [nTPM]":"10.8","Cell RNA - CAPAN-2 [nTPM]":"11.0","Cell RNA - Daudi [nTPM]":"10.6","Cell RNA - EFO-21 [nTPM]":"6.4","Cell RNA - fHDF\/TERT166 [nTPM]":"21.4","Cell RNA - GAMG [nTPM]":"13.0","Cell RNA - HaCaT [nTPM]":"8.2","Cell RNA - HAP1 [nTPM]":"5.9","Cell RNA - HBEC3-KT [nTPM]":"11.6","Cell RNA - HBF TERT88 [nTPM]":"5.5","Cell RNA - HDLM-2 [nTPM]":"21.0","Cell RNA - HEK 293 [nTPM]":"9.2","Cell RNA - HEL [nTPM]":"16.4","Cell RNA - HeLa [nTPM]":"9.6","Cell RNA - Hep G2 [nTPM]":"6.7","Cell RNA - HHSteC [nTPM]":"14.9","Cell RNA - HL-60 [nTPM]":"8.6","Cell RNA - HMC-1 [nTPM]":"11.0","Cell RNA - HSkMC [nTPM]":"10.2","Cell RNA - hTCEpi [nTPM]":"17.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.6","Cell RNA - hTERT-HME1 [nTPM]":"23.6","Cell RNA - hTERT-RPE1 [nTPM]":"15.5","Cell RNA - HUVEC TERT2 [nTPM]":"9.0","Cell RNA - JURKAT [nTPM]":"12.0","Cell RNA - K-562 [nTPM]":"19.7","Cell RNA - Karpas-707 [nTPM]":"31.9","Cell RNA - LHCN-M2 [nTPM]":"17.4","Cell RNA - MCF7 [nTPM]":"14.2","Cell RNA - MOLT-4 [nTPM]":"4.6","Cell RNA - NB-4 [nTPM]":"5.4","Cell RNA - NTERA-2 [nTPM]":"21.8","Cell RNA - OE19 [nTPM]":"16.7","Cell RNA - PC-3 [nTPM]":"11.3","Cell RNA - REH [nTPM]":"7.1","Cell RNA - RH-30 [nTPM]":"7.5","Cell RNA - RPMI-8226 [nTPM]":"11.2","Cell RNA - RPTEC TERT1 [nTPM]":"10.8","Cell RNA - RT4 [nTPM]":"24.8","Cell RNA - SCLC-21H [nTPM]":"8.3","Cell RNA - SH-SY5Y [nTPM]":"9.9","Cell RNA - SiHa [nTPM]":"16.7","Cell RNA - SK-BR-3 [nTPM]":"8.8","Cell RNA - SK-MEL-30 [nTPM]":"14.8","Cell RNA - SuSa [nTPM]":"10.0","Cell RNA - T-47d [nTPM]":"16.2","Cell RNA - THP-1 [nTPM]":"9.1","Cell RNA - TIME [nTPM]":"10.5","Cell RNA - U-138 MG [nTPM]":"9.1","Cell RNA - U-2 OS [nTPM]":"2.7","Cell RNA - U-2197 [nTPM]":"8.9","Cell RNA - U-251 MG [nTPM]":"7.8","Cell RNA - U-266\/70 [nTPM]":"25.6","Cell RNA - U-266\/84 [nTPM]":"19.8","Cell RNA - U-698 [nTPM]":"7.1","Cell RNA - U-87 MG [nTPM]":"14.6","Cell RNA - U-937 [nTPM]":"11.1","Cell RNA - WM-115 [nTPM]":"10.7","Blood RNA - basophil [nTPM]":"1.9","Blood RNA - classical monocyte [nTPM]":"0.8","Blood RNA - eosinophil [nTPM]":"0.8","Blood RNA - gdT-cell [nTPM]":"3.6","Blood RNA - intermediate monocyte [nTPM]":"2.0","Blood RNA - MAIT T-cell [nTPM]":"2.9","Blood RNA - memory B-cell [nTPM]":"1.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.9","Blood RNA - memory CD8 T-cell [nTPM]":"2.3","Blood RNA - myeloid DC [nTPM]":"0.8","Blood RNA - naive B-cell [nTPM]":"1.3","Blood RNA - naive CD4 T-cell [nTPM]":"2.4","Blood RNA - naive CD8 T-cell [nTPM]":"2.2","Blood RNA - neutrophil [nTPM]":"1.2","Blood RNA - NK-cell [nTPM]":"4.8","Blood RNA - non-classical monocyte [nTPM]":"5.1","Blood RNA - plasmacytoid DC [nTPM]":"1.9","Blood RNA - T-reg [nTPM]":"1.6","Blood RNA - total PBMC [nTPM]":"1.8","Brain RNA - amygdala [nTPM]":"4.9","Brain RNA - basal ganglia [nTPM]":"5.5","Brain RNA - cerebellum [nTPM]":"9.1","Brain RNA - cerebral cortex [nTPM]":"5.8","Brain RNA - hippocampal formation [nTPM]":"6.3","Brain RNA - hypothalamus [nTPM]":"5.4","Brain RNA - medulla oblongata [nTPM]":"5.9","Brain RNA - midbrain [nTPM]":"4.6","Brain RNA - pons [nTPM]":"6.3","Brain RNA - spinal cord [nTPM]":"4.1","Brain RNA - thalamus [nTPM]":"5.4","Brain RNA - white matter [nTPM]":"5.5","Single Cell Type RNA - Adipocytes [nTPM]":"3.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.5","Single Cell Type RNA - Astrocytes [nTPM]":"46.4","Single Cell Type RNA - B-cells [nTPM]":"4.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"12.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"8.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.9","Single Cell Type RNA - dendritic cells [nTPM]":"5.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.8","Single Cell Type RNA - Early spermatids [nTPM]":"5.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.0","Single Cell Type RNA - Endothelial cells [nTPM]":"3.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"86.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.4","Single Cell Type RNA - Fibroblasts [nTPM]":"5.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.0","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"7.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.2","Single Cell Type RNA - Hepatocytes [nTPM]":"18.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.6","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"99.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.2","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"5.1","Single Cell Type RNA - Langerhans cells [nTPM]":"2.1","Single Cell Type RNA - Late spermatids [nTPM]":"4.3","Single Cell Type RNA - Leydig cells [nTPM]":"4.4","Single Cell Type RNA - Macrophages [nTPM]":"4.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"45.9","Single Cell Type RNA - monocytes [nTPM]":"3.2","Single Cell Type RNA - Muller glia cells [nTPM]":"5.6","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"79.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"80.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.0","Single Cell Type RNA - Paneth cells [nTPM]":"2.9","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"4.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.8","Single Cell Type RNA - Spermatocytes [nTPM]":"5.2","Single Cell Type RNA - Spermatogonia [nTPM]":"11.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.1","Single Cell Type RNA - T-cells [nTPM]":"5.5","Single Cell Type RNA - Theca cells [nTPM]":"11.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.4","Single Cell Type RNA - Urothelial cells [nTPM]":"6.9"},{"Gene":"HMBS","Gene synonym":["PBGD","PORC","UPS"],"Ensembl":"ENSG00000256269","Gene description":"Hydroxymethylbilane synthase","Uniprot":["P08397"],"Chromosome":"11","Position":"119084866-119093549","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Heme biosynthesis","Porphyrin biosynthesis"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"bone marrow":"170.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"Erythroid cells":"935.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006114","HPA050659"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Lipid droplets"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"21000000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":["Lipid droplets"],"Subcellular additional location":null,"Antibody RRID":{"HPA006114":"AB_1079067","HPA050659":"AB_2681206"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.3","Tissue RNA - adrenal gland [nTPM]":"15.9","Tissue RNA - amygdala [nTPM]":"9.3","Tissue RNA - appendix [nTPM]":"9.3","Tissue RNA - basal ganglia [nTPM]":"10.4","Tissue RNA - bone marrow [nTPM]":"170.8","Tissue RNA - breast [nTPM]":"9.4","Tissue RNA - cerebellum [nTPM]":"11.5","Tissue RNA - cerebral cortex [nTPM]":"10.4","Tissue RNA - cervix [nTPM]":"7.9","Tissue RNA - choroid plexus [nTPM]":"10.1","Tissue RNA - colon [nTPM]":"13.7","Tissue RNA - duodenum [nTPM]":"12.5","Tissue RNA - endometrium 1 [nTPM]":"10.2","Tissue RNA - epididymis [nTPM]":"11.9","Tissue RNA - esophagus [nTPM]":"14.4","Tissue RNA - fallopian tube [nTPM]":"7.7","Tissue RNA - gallbladder [nTPM]":"4.0","Tissue RNA - heart muscle [nTPM]":"17.3","Tissue RNA - hippocampal formation [nTPM]":"9.1","Tissue RNA - hypothalamus [nTPM]":"10.0","Tissue RNA - kidney [nTPM]":"12.3","Tissue RNA - liver [nTPM]":"22.8","Tissue RNA - lung [nTPM]":"8.8","Tissue RNA - lymph node [nTPM]":"9.2","Tissue RNA - medulla oblongata [nTPM]":"10.7","Tissue RNA - midbrain [nTPM]":"10.2","Tissue RNA - ovary [nTPM]":"3.8","Tissue RNA - pancreas [nTPM]":"16.2","Tissue RNA - parathyroid gland [nTPM]":"9.2","Tissue RNA - pituitary gland [nTPM]":"8.5","Tissue RNA - placenta [nTPM]":"10.6","Tissue RNA - pons [nTPM]":"10.6","Tissue RNA - prostate [nTPM]":"8.6","Tissue RNA - rectum [nTPM]":"14.9","Tissue RNA - retina [nTPM]":"5.9","Tissue RNA - salivary gland [nTPM]":"9.9","Tissue RNA - seminal vesicle [nTPM]":"8.6","Tissue RNA - skeletal muscle [nTPM]":"30.4","Tissue RNA - skin 1 [nTPM]":"10.5","Tissue RNA - small intestine [nTPM]":"10.1","Tissue RNA - smooth muscle [nTPM]":"10.5","Tissue RNA - spinal cord [nTPM]":"10.4","Tissue RNA - spleen [nTPM]":"15.2","Tissue RNA - stomach 1 [nTPM]":"11.7","Tissue RNA - testis [nTPM]":"5.7","Tissue RNA - thalamus [nTPM]":"10.7","Tissue RNA - thymus [nTPM]":"7.6","Tissue RNA - thyroid gland [nTPM]":"8.9","Tissue RNA - tongue [nTPM]":"23.9","Tissue RNA - tonsil [nTPM]":"11.9","Tissue RNA - urinary bladder [nTPM]":"9.6","Tissue RNA - vagina [nTPM]":"8.0","Tissue RNA - white matter [nTPM]":"12.6","Cell RNA - A-431 [nTPM]":"40.0","Cell RNA - A549 [nTPM]":"59.9","Cell RNA - AF22 [nTPM]":"27.7","Cell RNA - AN3-CA [nTPM]":"47.5","Cell RNA - ASC diff [nTPM]":"21.6","Cell RNA - ASC TERT1 [nTPM]":"27.2","Cell RNA - BEWO [nTPM]":"41.7","Cell RNA - BJ [nTPM]":"31.1","Cell RNA - BJ hTERT+ [nTPM]":"34.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"45.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"38.2","Cell RNA - CACO-2 [nTPM]":"74.4","Cell RNA - CAPAN-2 [nTPM]":"60.2","Cell RNA - Daudi [nTPM]":"59.4","Cell RNA - EFO-21 [nTPM]":"68.3","Cell RNA - fHDF\/TERT166 [nTPM]":"40.1","Cell RNA - GAMG [nTPM]":"42.0","Cell RNA - HaCaT [nTPM]":"53.7","Cell RNA - HAP1 [nTPM]":"41.6","Cell RNA - HBEC3-KT [nTPM]":"60.1","Cell RNA - HBF TERT88 [nTPM]":"28.2","Cell RNA - HDLM-2 [nTPM]":"42.0","Cell RNA - HEK 293 [nTPM]":"42.4","Cell RNA - HEL [nTPM]":"97.2","Cell RNA - HeLa [nTPM]":"22.5","Cell RNA - Hep G2 [nTPM]":"55.0","Cell RNA - HHSteC [nTPM]":"40.8","Cell RNA - HL-60 [nTPM]":"37.6","Cell RNA - HMC-1 [nTPM]":"31.2","Cell RNA - HSkMC [nTPM]":"29.8","Cell RNA - hTCEpi [nTPM]":"38.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"71.5","Cell RNA - hTERT-HME1 [nTPM]":"53.1","Cell RNA - hTERT-RPE1 [nTPM]":"18.7","Cell RNA - HUVEC TERT2 [nTPM]":"21.5","Cell RNA - JURKAT [nTPM]":"55.9","Cell RNA - K-562 [nTPM]":"154.6","Cell RNA - Karpas-707 [nTPM]":"25.7","Cell RNA - LHCN-M2 [nTPM]":"35.9","Cell RNA - MCF7 [nTPM]":"158.4","Cell RNA - MOLT-4 [nTPM]":"36.3","Cell RNA - NB-4 [nTPM]":"72.6","Cell RNA - NTERA-2 [nTPM]":"32.1","Cell RNA - OE19 [nTPM]":"72.8","Cell RNA - PC-3 [nTPM]":"36.5","Cell RNA - REH [nTPM]":"41.9","Cell RNA - RH-30 [nTPM]":"27.8","Cell RNA - RPMI-8226 [nTPM]":"59.5","Cell RNA - RPTEC TERT1 [nTPM]":"45.3","Cell RNA - RT4 [nTPM]":"36.2","Cell RNA - SCLC-21H [nTPM]":"31.1","Cell RNA - SH-SY5Y [nTPM]":"41.4","Cell RNA - SiHa [nTPM]":"24.6","Cell RNA - SK-BR-3 [nTPM]":"38.4","Cell RNA - SK-MEL-30 [nTPM]":"29.3","Cell RNA - SuSa [nTPM]":"19.3","Cell RNA - T-47d [nTPM]":"64.7","Cell RNA - THP-1 [nTPM]":"52.3","Cell RNA - TIME [nTPM]":"20.0","Cell RNA - U-138 MG [nTPM]":"33.0","Cell RNA - U-2 OS [nTPM]":"25.5","Cell RNA - U-2197 [nTPM]":"32.9","Cell RNA - U-251 MG [nTPM]":"36.0","Cell RNA - U-266\/70 [nTPM]":"14.2","Cell RNA - U-266\/84 [nTPM]":"16.7","Cell RNA - U-698 [nTPM]":"36.6","Cell RNA - U-87 MG [nTPM]":"22.7","Cell RNA - U-937 [nTPM]":"47.4","Cell RNA - WM-115 [nTPM]":"40.0","Blood RNA - basophil [nTPM]":"48.5","Blood RNA - classical monocyte [nTPM]":"38.5","Blood RNA - eosinophil [nTPM]":"4.4","Blood RNA - gdT-cell [nTPM]":"13.6","Blood RNA - intermediate monocyte [nTPM]":"35.2","Blood RNA - MAIT T-cell [nTPM]":"17.8","Blood RNA - memory B-cell [nTPM]":"21.4","Blood RNA - memory CD4 T-cell [nTPM]":"12.5","Blood RNA - memory CD8 T-cell [nTPM]":"15.1","Blood RNA - myeloid DC [nTPM]":"52.8","Blood RNA - naive B-cell [nTPM]":"24.4","Blood RNA - naive CD4 T-cell [nTPM]":"19.7","Blood RNA - naive CD8 T-cell [nTPM]":"14.7","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"11.5","Blood RNA - non-classical monocyte [nTPM]":"22.2","Blood RNA - plasmacytoid DC [nTPM]":"35.1","Blood RNA - T-reg [nTPM]":"14.2","Blood RNA - total PBMC [nTPM]":"26.6","Brain RNA - amygdala [nTPM]":"9.3","Brain RNA - basal ganglia [nTPM]":"10.4","Brain RNA - cerebellum [nTPM]":"11.5","Brain RNA - cerebral cortex [nTPM]":"10.4","Brain RNA - hippocampal formation [nTPM]":"9.1","Brain RNA - hypothalamus [nTPM]":"10.0","Brain RNA - medulla oblongata [nTPM]":"10.7","Brain RNA - midbrain [nTPM]":"10.2","Brain RNA - pons [nTPM]":"10.6","Brain RNA - spinal cord [nTPM]":"10.4","Brain RNA - thalamus [nTPM]":"10.7","Brain RNA - white matter [nTPM]":"12.6","Single Cell Type RNA - Adipocytes [nTPM]":"5.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.0","Single Cell Type RNA - Astrocytes [nTPM]":"4.2","Single Cell Type RNA - B-cells [nTPM]":"12.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"26.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"5.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"12.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"57.8","Single Cell Type RNA - dendritic cells [nTPM]":"12.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"25.6","Single Cell Type RNA - Early spermatids [nTPM]":"1.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.4","Single Cell Type RNA - Endothelial cells [nTPM]":"6.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.2","Single Cell Type RNA - Erythroid cells [nTPM]":"935.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"31.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"61.1","Single Cell Type RNA - Fibroblasts [nTPM]":"9.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.8","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"6.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.6","Single Cell Type RNA - Hepatocytes [nTPM]":"23.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"29.1","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.1","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"13.0","Single Cell Type RNA - Langerhans cells [nTPM]":"10.4","Single Cell Type RNA - Late spermatids [nTPM]":"3.0","Single Cell Type RNA - Leydig cells [nTPM]":"5.9","Single Cell Type RNA - Macrophages [nTPM]":"9.5","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"15.3","Single Cell Type RNA - Muller glia cells [nTPM]":"7.5","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"23.3","Single Cell Type RNA - Paneth cells [nTPM]":"13.0","Single Cell Type RNA - Peritubular cells [nTPM]":"8.6","Single Cell Type RNA - Plasma cells [nTPM]":"25.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"24.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"25.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.7","Single Cell Type RNA - Spermatocytes [nTPM]":"1.7","Single Cell Type RNA - Spermatogonia [nTPM]":"32.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.3","Single Cell Type RNA - T-cells [nTPM]":"6.1","Single Cell Type RNA - Theca cells [nTPM]":"16.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"31.0","Single Cell Type RNA - Urothelial cells [nTPM]":"10.5"},{"Gene":"HMGCL","Gene synonym":["HL"],"Ensembl":"ENSG00000117305","Gene description":"3-hydroxy-3-methylglutaryl-CoA lyase","Uniprot":["P35914"],"Chromosome":"1","Position":"23801885-23838620","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Lyase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"322.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"172.4","Proximal tubular cells":"216.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004727"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"34000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA004727":"AB_1079074"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.67e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.07e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-3"},"Tissue RNA - adipose tissue [nTPM]":"27.5","Tissue RNA - adrenal gland [nTPM]":"63.0","Tissue RNA - amygdala [nTPM]":"26.3","Tissue RNA - appendix [nTPM]":"16.8","Tissue RNA - basal ganglia [nTPM]":"27.5","Tissue RNA - bone marrow [nTPM]":"7.5","Tissue RNA - breast [nTPM]":"25.8","Tissue RNA - cerebellum [nTPM]":"27.5","Tissue RNA - cerebral cortex [nTPM]":"28.3","Tissue RNA - cervix [nTPM]":"27.5","Tissue RNA - choroid plexus [nTPM]":"33.0","Tissue RNA - colon [nTPM]":"53.3","Tissue RNA - duodenum [nTPM]":"45.7","Tissue RNA - endometrium 1 [nTPM]":"20.2","Tissue RNA - epididymis [nTPM]":"47.2","Tissue RNA - esophagus [nTPM]":"32.8","Tissue RNA - fallopian tube [nTPM]":"35.6","Tissue RNA - gallbladder [nTPM]":"26.3","Tissue RNA - heart muscle [nTPM]":"42.5","Tissue RNA - hippocampal formation [nTPM]":"24.6","Tissue RNA - hypothalamus [nTPM]":"26.9","Tissue RNA - kidney [nTPM]":"115.5","Tissue RNA - liver [nTPM]":"322.5","Tissue RNA - lung [nTPM]":"23.6","Tissue RNA - lymph node [nTPM]":"21.7","Tissue RNA - medulla oblongata [nTPM]":"28.0","Tissue RNA - midbrain [nTPM]":"26.2","Tissue RNA - ovary [nTPM]":"21.6","Tissue RNA - pancreas [nTPM]":"33.4","Tissue RNA - parathyroid gland [nTPM]":"60.2","Tissue RNA - pituitary gland [nTPM]":"26.3","Tissue RNA - placenta [nTPM]":"19.9","Tissue RNA - pons [nTPM]":"27.7","Tissue RNA - prostate [nTPM]":"31.7","Tissue RNA - rectum [nTPM]":"52.9","Tissue RNA - retina [nTPM]":"16.1","Tissue RNA - salivary gland [nTPM]":"30.3","Tissue RNA - seminal vesicle [nTPM]":"27.9","Tissue RNA - skeletal muscle [nTPM]":"63.7","Tissue RNA - skin 1 [nTPM]":"25.5","Tissue RNA - small intestine [nTPM]":"40.0","Tissue RNA - smooth muscle [nTPM]":"23.3","Tissue RNA - spinal cord [nTPM]":"27.4","Tissue RNA - spleen [nTPM]":"26.8","Tissue RNA - stomach 1 [nTPM]":"40.9","Tissue RNA - testis [nTPM]":"17.9","Tissue RNA - thalamus [nTPM]":"30.1","Tissue RNA - thymus [nTPM]":"23.4","Tissue RNA - thyroid gland [nTPM]":"40.5","Tissue RNA - tongue [nTPM]":"70.2","Tissue RNA - tonsil [nTPM]":"25.1","Tissue RNA - urinary bladder [nTPM]":"28.6","Tissue RNA - vagina [nTPM]":"24.2","Tissue RNA - white matter [nTPM]":"29.6","Cell RNA - A-431 [nTPM]":"28.5","Cell RNA - A549 [nTPM]":"16.0","Cell RNA - AF22 [nTPM]":"17.7","Cell RNA - AN3-CA [nTPM]":"13.4","Cell RNA - ASC diff [nTPM]":"70.6","Cell RNA - ASC TERT1 [nTPM]":"53.5","Cell RNA - BEWO [nTPM]":"6.8","Cell RNA - BJ [nTPM]":"22.0","Cell RNA - BJ hTERT+ [nTPM]":"38.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"28.2","Cell RNA - CACO-2 [nTPM]":"10.2","Cell RNA - CAPAN-2 [nTPM]":"53.7","Cell RNA - Daudi [nTPM]":"14.8","Cell RNA - EFO-21 [nTPM]":"44.3","Cell RNA - fHDF\/TERT166 [nTPM]":"34.6","Cell RNA - GAMG [nTPM]":"19.0","Cell RNA - HaCaT [nTPM]":"22.4","Cell RNA - HAP1 [nTPM]":"21.3","Cell RNA - HBEC3-KT [nTPM]":"35.7","Cell RNA - HBF TERT88 [nTPM]":"25.2","Cell RNA - HDLM-2 [nTPM]":"30.4","Cell RNA - HEK 293 [nTPM]":"16.1","Cell RNA - HEL [nTPM]":"19.8","Cell RNA - HeLa [nTPM]":"13.8","Cell RNA - Hep G2 [nTPM]":"23.5","Cell RNA - HHSteC [nTPM]":"90.9","Cell RNA - HL-60 [nTPM]":"7.8","Cell RNA - HMC-1 [nTPM]":"12.7","Cell RNA - HSkMC [nTPM]":"62.4","Cell RNA - hTCEpi [nTPM]":"52.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"30.8","Cell RNA - hTERT-HME1 [nTPM]":"58.5","Cell RNA - hTERT-RPE1 [nTPM]":"62.5","Cell RNA - HUVEC TERT2 [nTPM]":"32.2","Cell RNA - JURKAT [nTPM]":"27.4","Cell RNA - K-562 [nTPM]":"20.6","Cell RNA - Karpas-707 [nTPM]":"20.3","Cell RNA - LHCN-M2 [nTPM]":"43.3","Cell RNA - MCF7 [nTPM]":"29.3","Cell RNA - MOLT-4 [nTPM]":"12.2","Cell RNA - NB-4 [nTPM]":"15.3","Cell RNA - NTERA-2 [nTPM]":"4.6","Cell RNA - OE19 [nTPM]":"77.4","Cell RNA - PC-3 [nTPM]":"22.1","Cell RNA - REH [nTPM]":"17.2","Cell RNA - RH-30 [nTPM]":"14.5","Cell RNA - RPMI-8226 [nTPM]":"27.9","Cell RNA - RPTEC TERT1 [nTPM]":"55.4","Cell RNA - RT4 [nTPM]":"14.5","Cell RNA - SCLC-21H [nTPM]":"14.8","Cell RNA - SH-SY5Y [nTPM]":"13.2","Cell RNA - SiHa [nTPM]":"28.6","Cell RNA - SK-BR-3 [nTPM]":"10.8","Cell RNA - SK-MEL-30 [nTPM]":"49.3","Cell RNA - SuSa [nTPM]":"23.3","Cell RNA - T-47d [nTPM]":"33.9","Cell RNA - THP-1 [nTPM]":"19.3","Cell RNA - TIME [nTPM]":"24.3","Cell RNA - U-138 MG [nTPM]":"19.3","Cell RNA - U-2 OS [nTPM]":"11.6","Cell RNA - U-2197 [nTPM]":"35.5","Cell RNA - U-251 MG [nTPM]":"9.7","Cell RNA - U-266\/70 [nTPM]":"28.7","Cell RNA - U-266\/84 [nTPM]":"15.2","Cell RNA - U-698 [nTPM]":"13.3","Cell RNA - U-87 MG [nTPM]":"47.7","Cell RNA - U-937 [nTPM]":"28.7","Cell RNA - WM-115 [nTPM]":"23.0","Blood RNA - basophil [nTPM]":"103.5","Blood RNA - classical monocyte [nTPM]":"67.0","Blood RNA - eosinophil [nTPM]":"66.0","Blood RNA - gdT-cell [nTPM]":"36.3","Blood RNA - intermediate monocyte [nTPM]":"66.0","Blood RNA - MAIT T-cell [nTPM]":"39.8","Blood RNA - memory B-cell [nTPM]":"45.9","Blood RNA - memory CD4 T-cell [nTPM]":"39.1","Blood RNA - memory CD8 T-cell [nTPM]":"42.1","Blood RNA - myeloid DC [nTPM]":"58.0","Blood RNA - naive B-cell [nTPM]":"51.2","Blood RNA - naive CD4 T-cell [nTPM]":"39.6","Blood RNA - naive CD8 T-cell [nTPM]":"37.7","Blood RNA - neutrophil [nTPM]":"25.5","Blood RNA - NK-cell [nTPM]":"54.4","Blood RNA - non-classical monocyte [nTPM]":"77.5","Blood RNA - plasmacytoid DC [nTPM]":"43.9","Blood RNA - T-reg [nTPM]":"45.5","Blood RNA - total PBMC [nTPM]":"61.7","Brain RNA - amygdala [nTPM]":"26.3","Brain RNA - basal ganglia [nTPM]":"27.5","Brain RNA - cerebellum [nTPM]":"27.5","Brain RNA - cerebral cortex [nTPM]":"28.3","Brain RNA - hippocampal formation [nTPM]":"24.6","Brain RNA - hypothalamus [nTPM]":"26.9","Brain RNA - medulla oblongata [nTPM]":"28.0","Brain RNA - midbrain [nTPM]":"26.2","Brain RNA - pons [nTPM]":"27.7","Brain RNA - spinal cord [nTPM]":"27.4","Brain RNA - thalamus [nTPM]":"30.1","Brain RNA - white matter [nTPM]":"29.6","Single Cell Type RNA - Adipocytes [nTPM]":"19.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.7","Single Cell Type RNA - Astrocytes [nTPM]":"14.0","Single Cell Type RNA - B-cells [nTPM]":"16.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"29.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"54.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"24.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"33.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"41.5","Single Cell Type RNA - Club cells [nTPM]":"30.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"49.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"43.0","Single Cell Type RNA - dendritic cells [nTPM]":"10.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"48.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"119.3","Single Cell Type RNA - Ductal cells [nTPM]":"57.7","Single Cell Type RNA - Early spermatids [nTPM]":"2.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.5","Single Cell Type RNA - Endothelial cells [nTPM]":"22.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.0","Single Cell Type RNA - Erythroid cells [nTPM]":"18.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"24.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"27.3","Single Cell Type RNA - Fibroblasts [nTPM]":"20.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"30.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"23.1","Single Cell Type RNA - granulocytes [nTPM]":"17.7","Single Cell Type RNA - Granulosa cells [nTPM]":"29.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"30.4","Single Cell Type RNA - Hepatocytes [nTPM]":"172.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"61.6","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"49.5","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"23.5","Single Cell Type RNA - Langerhans cells [nTPM]":"7.7","Single Cell Type RNA - Late spermatids [nTPM]":"3.6","Single Cell Type RNA - Leydig cells [nTPM]":"21.8","Single Cell Type RNA - Macrophages [nTPM]":"23.5","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"41.4","Single Cell Type RNA - Muller glia cells [nTPM]":"37.1","Single Cell Type RNA - NK-cells [nTPM]":"24.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"31.2","Single Cell Type RNA - Paneth cells [nTPM]":"53.8","Single Cell Type RNA - Peritubular cells [nTPM]":"24.5","Single Cell Type RNA - Plasma cells [nTPM]":"8.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"29.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"70.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"216.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"31.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"25.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.6","Single Cell Type RNA - Spermatocytes [nTPM]":"6.6","Single Cell Type RNA - Spermatogonia [nTPM]":"5.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"41.3","Single Cell Type RNA - T-cells [nTPM]":"15.2","Single Cell Type RNA - Theca cells [nTPM]":"65.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"48.9","Single Cell Type RNA - Urothelial cells [nTPM]":"24.3"},{"Gene":"HMGCS2","Gene synonym":[],"Ensembl":"ENSG00000134240","Gene description":"3-hydroxy-3-methylglutaryl-CoA synthase 2","Uniprot":["P54868"],"Chromosome":"1","Position":"119748002-119768905","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"liver":"2434.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"327.2","Hepatocytes":"1118.3","Intestinal goblet cells":"226.8","Paneth cells":"177.7","Undifferentiated cells":"282.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"liver cancer":"441.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"12","RNA cell line specific nTPM":{"OE19":"113.6","RT4":"201.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027423","HPA027442","CAB032906"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"830000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB032906":"AB_2118322","HPA027423":"AB_2672266","HPA027442":"AB_2672277"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.43e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.17e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.43e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-3"},"Tissue RNA - adipose tissue [nTPM]":"1.0","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"7.3","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"222.4","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"5.2","Tissue RNA - colon [nTPM]":"366.7","Tissue RNA - duodenum [nTPM]":"165.6","Tissue RNA - endometrium 1 [nTPM]":"1.4","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"4.3","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"4.3","Tissue RNA - heart muscle [nTPM]":"36.6","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"64.9","Tissue RNA - liver [nTPM]":"2434.1","Tissue RNA - lung [nTPM]":"2.2","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"20.1","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"34.0","Tissue RNA - rectum [nTPM]":"228.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"50.8","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"6.9","Tissue RNA - skin 1 [nTPM]":"14.2","Tissue RNA - small intestine [nTPM]":"151.8","Tissue RNA - smooth muscle [nTPM]":"23.7","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.6","Tissue RNA - stomach 1 [nTPM]":"101.2","Tissue RNA - testis [nTPM]":"35.6","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"0.6","Tissue RNA - tongue [nTPM]":"3.1","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"36.5","Tissue RNA - vagina [nTPM]":"2.7","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.6","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"12.9","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.5","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.9","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"113.6","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.7","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"201.6","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.8","Cell RNA - SiHa [nTPM]":"0.6","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"7.6","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"42.9","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"327.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"73.1","Single Cell Type RNA - Erythroid cells [nTPM]":"24.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"66.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.4","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"19.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.4","Single Cell Type RNA - Hepatocytes [nTPM]":"1118.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"226.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"26.1","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"3.9","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"177.7","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.4","Single Cell Type RNA - T-cells [nTPM]":"2.2","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"282.3","Single Cell Type RNA - Urothelial cells [nTPM]":"26.5"},{"Gene":"HMOX1","Gene synonym":["bK286B10","HO-1"],"Ensembl":"ENSG00000100292","Gene description":"Heme oxygenase 1","Uniprot":["P09601"],"Chromosome":"22","Position":"35380361-35394214","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"lymphoid tissue":"612.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endothelial cells":"327.1","Extravillous trophoblasts":"285.2","Hofbauer cells":"494.9","Kupffer cells":"954.1","Macrophages":"271.5","Syncytiotrophoblasts":"502.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"98.8","intermediate monocyte":"238.8","non-classical monocyte":"329.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"monocytes":"329.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"869.1","GAMG":"631.2","U-138 MG":"506.2","U-87 MG":"489.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000635","CAB017444"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Golgi apparatus","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB017444":"AB_10617276","HPA000635":"AB_1079089"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.59e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.54e-2"},"Tissue RNA - adipose tissue [nTPM]":"150.2","Tissue RNA - adrenal gland [nTPM]":"48.9","Tissue RNA - amygdala [nTPM]":"40.9","Tissue RNA - appendix [nTPM]":"64.6","Tissue RNA - basal ganglia [nTPM]":"48.8","Tissue RNA - bone marrow [nTPM]":"99.3","Tissue RNA - breast [nTPM]":"20.6","Tissue RNA - cerebellum [nTPM]":"42.4","Tissue RNA - cerebral cortex [nTPM]":"66.3","Tissue RNA - cervix [nTPM]":"28.2","Tissue RNA - choroid plexus [nTPM]":"46.4","Tissue RNA - colon [nTPM]":"35.2","Tissue RNA - duodenum [nTPM]":"106.0","Tissue RNA - endometrium 1 [nTPM]":"10.4","Tissue RNA - epididymis [nTPM]":"7.6","Tissue RNA - esophagus [nTPM]":"48.4","Tissue RNA - fallopian tube [nTPM]":"40.7","Tissue RNA - gallbladder [nTPM]":"52.6","Tissue RNA - heart muscle [nTPM]":"18.2","Tissue RNA - hippocampal formation [nTPM]":"40.6","Tissue RNA - hypothalamus [nTPM]":"46.6","Tissue RNA - kidney [nTPM]":"96.2","Tissue RNA - liver [nTPM]":"136.5","Tissue RNA - lung [nTPM]":"113.6","Tissue RNA - lymph node [nTPM]":"57.2","Tissue RNA - medulla oblongata [nTPM]":"52.3","Tissue RNA - midbrain [nTPM]":"46.5","Tissue RNA - ovary [nTPM]":"139.0","Tissue RNA - pancreas [nTPM]":"41.7","Tissue RNA - parathyroid gland [nTPM]":"7.4","Tissue RNA - pituitary gland [nTPM]":"9.6","Tissue RNA - placenta [nTPM]":"72.2","Tissue RNA - pons [nTPM]":"56.3","Tissue RNA - prostate [nTPM]":"6.7","Tissue RNA - rectum [nTPM]":"31.1","Tissue RNA - retina [nTPM]":"1.7","Tissue RNA - salivary gland [nTPM]":"15.1","Tissue RNA - seminal vesicle [nTPM]":"4.0","Tissue RNA - skeletal muscle [nTPM]":"107.1","Tissue RNA - skin 1 [nTPM]":"74.1","Tissue RNA - small intestine [nTPM]":"64.5","Tissue RNA - smooth muscle [nTPM]":"38.7","Tissue RNA - spinal cord [nTPM]":"45.9","Tissue RNA - spleen [nTPM]":"612.2","Tissue RNA - stomach 1 [nTPM]":"19.9","Tissue RNA - testis [nTPM]":"17.8","Tissue RNA - thalamus [nTPM]":"60.7","Tissue RNA - thymus [nTPM]":"25.1","Tissue RNA - thyroid gland [nTPM]":"11.3","Tissue RNA - tongue [nTPM]":"21.4","Tissue RNA - tonsil [nTPM]":"49.4","Tissue RNA - urinary bladder [nTPM]":"46.2","Tissue RNA - vagina [nTPM]":"29.2","Tissue RNA - white matter [nTPM]":"56.2","Cell RNA - A-431 [nTPM]":"12.2","Cell RNA - A549 [nTPM]":"179.1","Cell RNA - AF22 [nTPM]":"1.8","Cell RNA - AN3-CA [nTPM]":"37.7","Cell RNA - ASC diff [nTPM]":"170.9","Cell RNA - ASC TERT1 [nTPM]":"49.6","Cell RNA - BEWO [nTPM]":"869.1","Cell RNA - BJ [nTPM]":"83.2","Cell RNA - BJ hTERT+ [nTPM]":"57.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"42.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"48.6","Cell RNA - CACO-2 [nTPM]":"82.1","Cell RNA - CAPAN-2 [nTPM]":"11.3","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"18.3","Cell RNA - fHDF\/TERT166 [nTPM]":"83.3","Cell RNA - GAMG [nTPM]":"631.2","Cell RNA - HaCaT [nTPM]":"10.1","Cell RNA - HAP1 [nTPM]":"11.4","Cell RNA - HBEC3-KT [nTPM]":"1.9","Cell RNA - HBF TERT88 [nTPM]":"16.1","Cell RNA - HDLM-2 [nTPM]":"308.6","Cell RNA - HEK 293 [nTPM]":"9.2","Cell RNA - HEL [nTPM]":"4.3","Cell RNA - HeLa [nTPM]":"51.5","Cell RNA - Hep G2 [nTPM]":"179.3","Cell RNA - HHSteC [nTPM]":"218.9","Cell RNA - HL-60 [nTPM]":"11.5","Cell RNA - HMC-1 [nTPM]":"54.8","Cell RNA - HSkMC [nTPM]":"146.3","Cell RNA - hTCEpi [nTPM]":"4.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"282.3","Cell RNA - hTERT-HME1 [nTPM]":"19.7","Cell RNA - hTERT-RPE1 [nTPM]":"74.6","Cell RNA - HUVEC TERT2 [nTPM]":"130.9","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"87.4","Cell RNA - LHCN-M2 [nTPM]":"152.5","Cell RNA - MCF7 [nTPM]":"6.9","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"4.3","Cell RNA - NTERA-2 [nTPM]":"18.1","Cell RNA - OE19 [nTPM]":"130.4","Cell RNA - PC-3 [nTPM]":"20.7","Cell RNA - REH [nTPM]":"1.2","Cell RNA - RH-30 [nTPM]":"15.6","Cell RNA - RPMI-8226 [nTPM]":"28.4","Cell RNA - RPTEC TERT1 [nTPM]":"35.2","Cell RNA - RT4 [nTPM]":"104.5","Cell RNA - SCLC-21H [nTPM]":"2.7","Cell RNA - SH-SY5Y [nTPM]":"2.4","Cell RNA - SiHa [nTPM]":"215.8","Cell RNA - SK-BR-3 [nTPM]":"19.1","Cell RNA - SK-MEL-30 [nTPM]":"15.5","Cell RNA - SuSa [nTPM]":"92.5","Cell RNA - T-47d [nTPM]":"8.9","Cell RNA - THP-1 [nTPM]":"3.0","Cell RNA - TIME [nTPM]":"44.3","Cell RNA - U-138 MG [nTPM]":"506.2","Cell RNA - U-2 OS [nTPM]":"22.1","Cell RNA - U-2197 [nTPM]":"82.5","Cell RNA - U-251 MG [nTPM]":"82.5","Cell RNA - U-266\/70 [nTPM]":"53.5","Cell RNA - U-266\/84 [nTPM]":"77.0","Cell RNA - U-698 [nTPM]":"9.3","Cell RNA - U-87 MG [nTPM]":"489.4","Cell RNA - U-937 [nTPM]":"5.7","Cell RNA - WM-115 [nTPM]":"8.6","Blood RNA - basophil [nTPM]":"11.3","Blood RNA - classical monocyte [nTPM]":"98.8","Blood RNA - eosinophil [nTPM]":"7.7","Blood RNA - gdT-cell [nTPM]":"1.1","Blood RNA - intermediate monocyte [nTPM]":"238.8","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"24.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.7","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"44.6","Blood RNA - naive B-cell [nTPM]":"2.9","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"47.1","Blood RNA - NK-cell [nTPM]":"5.3","Blood RNA - non-classical monocyte [nTPM]":"329.2","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"1.8","Blood RNA - total PBMC [nTPM]":"70.9","Brain RNA - amygdala [nTPM]":"40.9","Brain RNA - basal ganglia [nTPM]":"48.8","Brain RNA - cerebellum [nTPM]":"42.4","Brain RNA - cerebral cortex [nTPM]":"66.3","Brain RNA - hippocampal formation [nTPM]":"40.6","Brain RNA - hypothalamus [nTPM]":"46.6","Brain RNA - medulla oblongata [nTPM]":"52.3","Brain RNA - midbrain [nTPM]":"46.5","Brain RNA - pons [nTPM]":"56.3","Brain RNA - spinal cord [nTPM]":"45.9","Brain RNA - thalamus [nTPM]":"60.7","Brain RNA - white matter [nTPM]":"56.2","Single Cell Type RNA - Adipocytes [nTPM]":"19.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"11.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"10.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"50.5","Single Cell Type RNA - dendritic cells [nTPM]":"3.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"59.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"13.6","Single Cell Type RNA - Early spermatids [nTPM]":"2.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"39.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.9","Single Cell Type RNA - Endothelial cells [nTPM]":"327.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"285.2","Single Cell Type RNA - Fibroblasts [nTPM]":"64.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"74.6","Single Cell Type RNA - granulocytes [nTPM]":"11.4","Single Cell Type RNA - Granulosa cells [nTPM]":"98.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.6","Single Cell Type RNA - Hepatocytes [nTPM]":"23.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"494.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.3","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"954.1","Single Cell Type RNA - Langerhans cells [nTPM]":"175.8","Single Cell Type RNA - Late spermatids [nTPM]":"4.1","Single Cell Type RNA - Leydig cells [nTPM]":"31.1","Single Cell Type RNA - Macrophages [nTPM]":"271.5","Single Cell Type RNA - Melanocytes [nTPM]":"35.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"184.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.3","Single Cell Type RNA - Paneth cells [nTPM]":"26.1","Single Cell Type RNA - Peritubular cells [nTPM]":"5.3","Single Cell Type RNA - Plasma cells [nTPM]":"2.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"110.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"61.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"157.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"40.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"52.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.9","Single Cell Type RNA - Spermatogonia [nTPM]":"4.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"502.0","Single Cell Type RNA - T-cells [nTPM]":"6.8","Single Cell Type RNA - Theca cells [nTPM]":"6.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.1","Single Cell Type RNA - Urothelial cells [nTPM]":"118.3"},{"Gene":"HNMT","Gene synonym":[],"Ensembl":"ENSG00000150540","Gene description":"Histamine N-methyltransferase","Uniprot":["P50135"],"Chromosome":"2","Position":"137964020-138016364","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"245.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"299.3","Kupffer cells":"263.7","Proximal tubular cells":"268.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"21","RNA blood cell specific nTPM":{"classical monocyte":"110.9","intermediate monocyte":"89.8","myeloid DC":"68.3","non-classical monocyte":"52.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"23","RNA blood lineage specific nTPM":{"dendritic cells":"68.3","monocytes":"110.9"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"227.2","HSkMC":"87.9","RT4":"117.1","SuSa":"107.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035480","HPA035481","HPA073754"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"130000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"HPA035480":"AB_2674645","HPA035481":"AB_10672094","HPA073754":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.41e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.68e-4"},"Tissue RNA - adipose tissue [nTPM]":"70.4","Tissue RNA - adrenal gland [nTPM]":"18.2","Tissue RNA - amygdala [nTPM]":"13.0","Tissue RNA - appendix [nTPM]":"41.7","Tissue RNA - basal ganglia [nTPM]":"13.3","Tissue RNA - bone marrow [nTPM]":"12.6","Tissue RNA - breast [nTPM]":"62.3","Tissue RNA - cerebellum [nTPM]":"13.1","Tissue RNA - cerebral cortex [nTPM]":"18.8","Tissue RNA - cervix [nTPM]":"57.3","Tissue RNA - choroid plexus [nTPM]":"19.2","Tissue RNA - colon [nTPM]":"53.9","Tissue RNA - duodenum [nTPM]":"29.3","Tissue RNA - endometrium 1 [nTPM]":"62.8","Tissue RNA - epididymis [nTPM]":"27.1","Tissue RNA - esophagus [nTPM]":"17.5","Tissue RNA - fallopian tube [nTPM]":"34.5","Tissue RNA - gallbladder [nTPM]":"68.7","Tissue RNA - heart muscle [nTPM]":"21.7","Tissue RNA - hippocampal formation [nTPM]":"15.6","Tissue RNA - hypothalamus [nTPM]":"19.1","Tissue RNA - kidney [nTPM]":"109.7","Tissue RNA - liver [nTPM]":"245.9","Tissue RNA - lung [nTPM]":"49.0","Tissue RNA - lymph node [nTPM]":"35.1","Tissue RNA - medulla oblongata [nTPM]":"16.0","Tissue RNA - midbrain [nTPM]":"15.3","Tissue RNA - ovary [nTPM]":"91.0","Tissue RNA - pancreas [nTPM]":"29.0","Tissue RNA - parathyroid gland [nTPM]":"40.2","Tissue RNA - pituitary gland [nTPM]":"9.5","Tissue RNA - placenta [nTPM]":"46.8","Tissue RNA - pons [nTPM]":"18.1","Tissue RNA - prostate [nTPM]":"37.0","Tissue RNA - rectum [nTPM]":"56.4","Tissue RNA - retina [nTPM]":"6.1","Tissue RNA - salivary gland [nTPM]":"30.5","Tissue RNA - seminal vesicle [nTPM]":"44.3","Tissue RNA - skeletal muscle [nTPM]":"5.9","Tissue RNA - skin 1 [nTPM]":"17.4","Tissue RNA - small intestine [nTPM]":"29.1","Tissue RNA - smooth muscle [nTPM]":"33.1","Tissue RNA - spinal cord [nTPM]":"16.1","Tissue RNA - spleen [nTPM]":"37.5","Tissue RNA - stomach 1 [nTPM]":"29.1","Tissue RNA - testis [nTPM]":"10.3","Tissue RNA - thalamus [nTPM]":"14.5","Tissue RNA - thymus [nTPM]":"8.2","Tissue RNA - thyroid gland [nTPM]":"14.6","Tissue RNA - tongue [nTPM]":"11.9","Tissue RNA - tonsil [nTPM]":"16.4","Tissue RNA - urinary bladder [nTPM]":"49.7","Tissue RNA - vagina [nTPM]":"24.5","Tissue RNA - white matter [nTPM]":"22.2","Cell RNA - A-431 [nTPM]":"0.7","Cell RNA - A549 [nTPM]":"0.9","Cell RNA - AF22 [nTPM]":"5.6","Cell RNA - AN3-CA [nTPM]":"14.6","Cell RNA - ASC diff [nTPM]":"61.9","Cell RNA - ASC TERT1 [nTPM]":"64.6","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"3.9","Cell RNA - BJ hTERT+ [nTPM]":"6.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.3","Cell RNA - CACO-2 [nTPM]":"29.7","Cell RNA - CAPAN-2 [nTPM]":"15.7","Cell RNA - Daudi [nTPM]":"0.9","Cell RNA - EFO-21 [nTPM]":"50.2","Cell RNA - fHDF\/TERT166 [nTPM]":"17.0","Cell RNA - GAMG [nTPM]":"0.8","Cell RNA - HaCaT [nTPM]":"1.1","Cell RNA - HAP1 [nTPM]":"11.9","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.7","Cell RNA - HEK 293 [nTPM]":"4.9","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"44.5","Cell RNA - Hep G2 [nTPM]":"227.2","Cell RNA - HHSteC [nTPM]":"28.0","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"87.9","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.5","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"4.7","Cell RNA - HUVEC TERT2 [nTPM]":"15.9","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.5","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"47.4","Cell RNA - MCF7 [nTPM]":"3.7","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"28.1","Cell RNA - OE19 [nTPM]":"39.3","Cell RNA - PC-3 [nTPM]":"5.6","Cell RNA - REH [nTPM]":"0.5","Cell RNA - RH-30 [nTPM]":"1.5","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"67.9","Cell RNA - RT4 [nTPM]":"117.1","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.8","Cell RNA - SiHa [nTPM]":"22.1","Cell RNA - SK-BR-3 [nTPM]":"28.4","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"107.9","Cell RNA - T-47d [nTPM]":"1.0","Cell RNA - THP-1 [nTPM]":"53.2","Cell RNA - TIME [nTPM]":"4.8","Cell RNA - U-138 MG [nTPM]":"4.8","Cell RNA - U-2 OS [nTPM]":"11.8","Cell RNA - U-2197 [nTPM]":"6.2","Cell RNA - U-251 MG [nTPM]":"16.3","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.7","Cell RNA - U-87 MG [nTPM]":"20.9","Cell RNA - U-937 [nTPM]":"27.8","Cell RNA - WM-115 [nTPM]":"3.3","Blood RNA - basophil [nTPM]":"1.3","Blood RNA - classical monocyte [nTPM]":"110.9","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"89.8","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"68.3","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"3.9","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"52.2","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"32.6","Brain RNA - amygdala [nTPM]":"13.0","Brain RNA - basal ganglia [nTPM]":"13.3","Brain RNA - cerebellum [nTPM]":"13.1","Brain RNA - cerebral cortex [nTPM]":"18.8","Brain RNA - hippocampal formation [nTPM]":"15.6","Brain RNA - hypothalamus [nTPM]":"19.1","Brain RNA - medulla oblongata [nTPM]":"16.0","Brain RNA - midbrain [nTPM]":"15.3","Brain RNA - pons [nTPM]":"18.1","Brain RNA - spinal cord [nTPM]":"16.1","Brain RNA - thalamus [nTPM]":"14.5","Brain RNA - white matter [nTPM]":"22.2","Single Cell Type RNA - Adipocytes [nTPM]":"15.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"44.1","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"5.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"35.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"81.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"64.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"30.7","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"78.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"65.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"133.0","Single Cell Type RNA - Club cells [nTPM]":"88.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"60.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"54.9","Single Cell Type RNA - dendritic cells [nTPM]":"2.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"59.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"123.3","Single Cell Type RNA - Ductal cells [nTPM]":"122.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"28.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"50.6","Single Cell Type RNA - Endothelial cells [nTPM]":"9.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.4","Single Cell Type RNA - Erythroid cells [nTPM]":"16.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"48.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"81.6","Single Cell Type RNA - Fibroblasts [nTPM]":"54.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"115.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"17.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.2","Single Cell Type RNA - Hepatocytes [nTPM]":"165.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"299.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"67.8","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"263.7","Single Cell Type RNA - Langerhans cells [nTPM]":"97.2","Single Cell Type RNA - Late spermatids [nTPM]":"4.2","Single Cell Type RNA - Leydig cells [nTPM]":"131.4","Single Cell Type RNA - Macrophages [nTPM]":"127.4","Single Cell Type RNA - Melanocytes [nTPM]":"56.9","Single Cell Type RNA - Microglial cells [nTPM]":"31.9","Single Cell Type RNA - monocytes [nTPM]":"122.0","Single Cell Type RNA - Muller glia cells [nTPM]":"25.5","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"45.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"71.0","Single Cell Type RNA - Paneth cells [nTPM]":"108.6","Single Cell Type RNA - Peritubular cells [nTPM]":"105.3","Single Cell Type RNA - Plasma cells [nTPM]":"0.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"39.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"31.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"268.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"38.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"78.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"55.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"55.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"33.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"25.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"37.6","Single Cell Type RNA - T-cells [nTPM]":"4.0","Single Cell Type RNA - Theca cells [nTPM]":"43.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"83.5","Single Cell Type RNA - Urothelial cells [nTPM]":"126.1"},{"Gene":"HOGA1","Gene synonym":["C10orf65","DHDPS2","DHDPSL","FLJ37472","NPL2"],"Ensembl":"ENSG00000241935","Gene description":"4-hydroxy-2-oxoglutarate aldolase 1","Uniprot":["Q86XE5"],"Chromosome":"10","Position":"97584323-97612802","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Lyase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"51.8","liver":"54.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"35.8","Distal tubular cells":"29.4","Hepatocytes":"43.3","Late spermatids":"18.4","Proximal tubular cells":"98.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"liver cancer":"4.5","renal cancer":"9.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AN3-CA":"7.8","EFO-21":"9.7","Hep G2":"26.1","RPTEC TERT1":"31.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039466"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"16000","Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039466":"AB_2676522"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.08e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-4"},"Tissue RNA - adipose tissue [nTPM]":"4.1","Tissue RNA - adrenal gland [nTPM]":"8.3","Tissue RNA - amygdala [nTPM]":"5.8","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"7.4","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"1.9","Tissue RNA - cerebellum [nTPM]":"9.3","Tissue RNA - cerebral cortex [nTPM]":"5.0","Tissue RNA - cervix [nTPM]":"0.7","Tissue RNA - choroid plexus [nTPM]":"11.4","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"1.1","Tissue RNA - epididymis [nTPM]":"3.7","Tissue RNA - esophagus [nTPM]":"1.0","Tissue RNA - fallopian tube [nTPM]":"2.0","Tissue RNA - gallbladder [nTPM]":"2.5","Tissue RNA - heart muscle [nTPM]":"21.1","Tissue RNA - hippocampal formation [nTPM]":"4.4","Tissue RNA - hypothalamus [nTPM]":"6.5","Tissue RNA - kidney [nTPM]":"51.8","Tissue RNA - liver [nTPM]":"54.8","Tissue RNA - lung [nTPM]":"1.4","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"8.2","Tissue RNA - midbrain [nTPM]":"9.2","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"15.3","Tissue RNA - parathyroid gland [nTPM]":"5.7","Tissue RNA - pituitary gland [nTPM]":"3.6","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"8.3","Tissue RNA - prostate [nTPM]":"1.1","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.8","Tissue RNA - salivary gland [nTPM]":"1.7","Tissue RNA - seminal vesicle [nTPM]":"2.1","Tissue RNA - skeletal muscle [nTPM]":"3.4","Tissue RNA - skin 1 [nTPM]":"1.5","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"7.3","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"7.9","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"1.8","Tissue RNA - tongue [nTPM]":"12.1","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"0.9","Tissue RNA - white matter [nTPM]":"10.3","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"3.7","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"7.8","Cell RNA - ASC diff [nTPM]":"1.5","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"3.0","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"9.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"2.6","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"4.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"1.4","Cell RNA - Hep G2 [nTPM]":"26.1","Cell RNA - HHSteC [nTPM]":"1.1","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"1.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.4","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"0.6","Cell RNA - MCF7 [nTPM]":"1.6","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.6","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"31.5","Cell RNA - RT4 [nTPM]":"0.6","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"1.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"1.3","Cell RNA - SK-MEL-30 [nTPM]":"0.5","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"2.8","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.8","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"0.9","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"2.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"5.8","Brain RNA - basal ganglia [nTPM]":"7.4","Brain RNA - cerebellum [nTPM]":"9.3","Brain RNA - cerebral cortex [nTPM]":"5.0","Brain RNA - hippocampal formation [nTPM]":"4.4","Brain RNA - hypothalamus [nTPM]":"6.5","Brain RNA - medulla oblongata [nTPM]":"8.2","Brain RNA - midbrain [nTPM]":"9.2","Brain RNA - pons [nTPM]":"8.3","Brain RNA - spinal cord [nTPM]":"7.3","Brain RNA - thalamus [nTPM]":"7.9","Brain RNA - white matter [nTPM]":"10.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"7.2","Single Cell Type RNA - B-cells [nTPM]":"1.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"35.8","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"29.4","Single Cell Type RNA - Ductal cells [nTPM]":"5.9","Single Cell Type RNA - Early spermatids [nTPM]":"3.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"43.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"18.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"98.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"HP","Gene synonym":[],"Ensembl":"ENSG00000257017","Gene description":"Haptoglobin","Uniprot":["P00738"],"Chromosome":"16","Position":"72054505-72061055","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Acute phase","Immunity"],"Molecular function":["Antibiotic","Antimicrobial","Antioxidant","Serine protease homolog"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"91","RNA tissue specific nTPM":{"liver":"61113.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"43","RNA single cell type specific nTPM":{"Hepatocytes":"59512.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"81","RNA cancer specific FPKM":{"liver cancer":"1297.4"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"medulla oblongata":"29.7"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"49.3","eosinophil":"80.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"80.2","monocytes":"49.3"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Hep G2":"232.2","HSkMC":"121.4"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003787","HPA047750","HPA066795"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":998000000000,"Blood concentration - Conc. blood MS [pg\/L]":"100000000000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB003787":null,"HPA047750":"AB_2680146","HPA066795":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.94e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Tissue RNA - adipose tissue [nTPM]":"673.1","Tissue RNA - adrenal gland [nTPM]":"11.4","Tissue RNA - amygdala [nTPM]":"1.3","Tissue RNA - appendix [nTPM]":"26.9","Tissue RNA - basal ganglia [nTPM]":"1.7","Tissue RNA - bone marrow [nTPM]":"231.5","Tissue RNA - breast [nTPM]":"34.2","Tissue RNA - cerebellum [nTPM]":"1.4","Tissue RNA - cerebral cortex [nTPM]":"2.9","Tissue RNA - cervix [nTPM]":"71.9","Tissue RNA - choroid plexus [nTPM]":"3.6","Tissue RNA - colon [nTPM]":"3.6","Tissue RNA - duodenum [nTPM]":"1.5","Tissue RNA - endometrium 1 [nTPM]":"3.5","Tissue RNA - epididymis [nTPM]":"2.9","Tissue RNA - esophagus [nTPM]":"5.3","Tissue RNA - fallopian tube [nTPM]":"74.6","Tissue RNA - gallbladder [nTPM]":"1.3","Tissue RNA - heart muscle [nTPM]":"146.7","Tissue RNA - hippocampal formation [nTPM]":"1.4","Tissue RNA - hypothalamus [nTPM]":"1.4","Tissue RNA - kidney [nTPM]":"19.8","Tissue RNA - liver [nTPM]":"61113.6","Tissue RNA - lung [nTPM]":"91.3","Tissue RNA - lymph node [nTPM]":"1.7","Tissue RNA - medulla oblongata [nTPM]":"29.7","Tissue RNA - midbrain [nTPM]":"2.0","Tissue RNA - ovary [nTPM]":"9.9","Tissue RNA - pancreas [nTPM]":"7.6","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"49.9","Tissue RNA - placenta [nTPM]":"2.5","Tissue RNA - pons [nTPM]":"3.7","Tissue RNA - prostate [nTPM]":"7.3","Tissue RNA - rectum [nTPM]":"0.6","Tissue RNA - retina [nTPM]":"0.7","Tissue RNA - salivary gland [nTPM]":"6.1","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"5.0","Tissue RNA - skin 1 [nTPM]":"3.4","Tissue RNA - small intestine [nTPM]":"4.4","Tissue RNA - smooth muscle [nTPM]":"4.5","Tissue RNA - spinal cord [nTPM]":"2.3","Tissue RNA - spleen [nTPM]":"72.0","Tissue RNA - stomach 1 [nTPM]":"6.2","Tissue RNA - testis [nTPM]":"2.1","Tissue RNA - thalamus [nTPM]":"8.3","Tissue RNA - thymus [nTPM]":"2.7","Tissue RNA - thyroid gland [nTPM]":"6.3","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"3.0","Tissue RNA - urinary bladder [nTPM]":"3.8","Tissue RNA - vagina [nTPM]":"3.3","Tissue RNA - white matter [nTPM]":"5.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"6.6","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"8.5","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"2.6","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"11.2","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"232.2","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"33.3","Cell RNA - HMC-1 [nTPM]":"6.2","Cell RNA - HSkMC [nTPM]":"121.4","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"8.8","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"2.0","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"2.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"1.1","Cell RNA - RH-30 [nTPM]":"23.6","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"16.2","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"6.8","Cell RNA - TIME [nTPM]":"5.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"3.9","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"14.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"12.7","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"6.2","Blood RNA - classical monocyte [nTPM]":"49.3","Blood RNA - eosinophil [nTPM]":"80.2","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"2.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"8.7","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"14.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"2.1","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"15.2","Brain RNA - amygdala [nTPM]":"1.3","Brain RNA - basal ganglia [nTPM]":"1.7","Brain RNA - cerebellum [nTPM]":"1.4","Brain RNA - cerebral cortex [nTPM]":"2.9","Brain RNA - hippocampal formation [nTPM]":"1.4","Brain RNA - hypothalamus [nTPM]":"1.4","Brain RNA - medulla oblongata [nTPM]":"29.7","Brain RNA - midbrain [nTPM]":"2.0","Brain RNA - pons [nTPM]":"3.7","Brain RNA - spinal cord [nTPM]":"2.3","Brain RNA - thalamus [nTPM]":"8.3","Brain RNA - white matter [nTPM]":"5.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"228.7","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"96.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"66.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"1085.2","Single Cell Type RNA - Club cells [nTPM]":"8.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"56.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1128.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"45.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.3","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1038.7","Single Cell Type RNA - Hepatocytes [nTPM]":"59512.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"1381.4","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"10.2","Single Cell Type RNA - Macrophages [nTPM]":"7.8","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.3","Single Cell Type RNA - Muller glia cells [nTPM]":"1.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"90.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"HPCA","Gene synonym":["DYT2"],"Ensembl":"ENSG00000121905","Gene description":"Hippocalcin","Uniprot":["P84074"],"Chromosome":"1","Position":"32885994-32898441","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Dystonia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"brain":"517.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Bipolar cells":"198.3","Early spermatids":"155.4","Late spermatids":"119.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"glioma":"8.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"SCLC-21H":"4.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"basal ganglia":"1309.6","hippocampal formation":"990.7"},"Antibody":["CAB012340","HPA043245"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB012340":"AB_2120209","HPA043245":"AB_2678385"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.4","Tissue RNA - amygdala [nTPM]":"99.4","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"517.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"50.3","Tissue RNA - cerebral cortex [nTPM]":"322.2","Tissue RNA - cervix [nTPM]":"0.7","Tissue RNA - choroid plexus [nTPM]":"37.5","Tissue RNA - colon [nTPM]":"0.7","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.5","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"326.8","Tissue RNA - hypothalamus [nTPM]":"52.2","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"43.0","Tissue RNA - midbrain [nTPM]":"54.8","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"0.5","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"1.8","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"41.6","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"18.4","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"54.8","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"3.6","Tissue RNA - thalamus [nTPM]":"105.8","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"82.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.6","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.4","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"4.9","Cell RNA - SH-SY5Y [nTPM]":"0.6","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"99.4","Brain RNA - basal ganglia [nTPM]":"517.5","Brain RNA - cerebellum [nTPM]":"50.3","Brain RNA - cerebral cortex [nTPM]":"322.2","Brain RNA - hippocampal formation [nTPM]":"326.8","Brain RNA - hypothalamus [nTPM]":"52.2","Brain RNA - medulla oblongata [nTPM]":"43.0","Brain RNA - midbrain [nTPM]":"54.8","Brain RNA - pons [nTPM]":"41.6","Brain RNA - spinal cord [nTPM]":"54.8","Brain RNA - thalamus [nTPM]":"105.8","Brain RNA - white matter [nTPM]":"82.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"3.6","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"198.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"155.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"21.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"119.7","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"9.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"5.9","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"4.2","Single Cell Type RNA - Spermatogonia [nTPM]":"8.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.2","Single Cell Type RNA - Urothelial cells [nTPM]":"1.4"},{"Gene":"HPGD","Gene synonym":["SDR36C1"],"Ensembl":"ENSG00000164120","Gene description":"15-hydroxyprostaglandin dehydrogenase","Uniprot":["P15428"],"Chromosome":"4","Position":"174490175-174523154","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism","Prostaglandin metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"stomach 1":"235.0","urinary bladder":"376.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"457.8","Extravillous trophoblasts":"701.7","granulocytes":"864.5","Proximal enterocytes":"500.6","Urothelial cells":"922.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"urothelial cancer":"52.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"123.7","T-reg":"45.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"73","RNA blood lineage specific nTPM":{"granulocytes":"123.7","T-cells":"45.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"157.8","ASC diff":"110.6","HEL":"355.0","OE19":"102.1","RT4":"565.7","SuSa":"121.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004919","HPA005679"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"20000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA004919":"AB_1079081","HPA005679":"AB_1079080"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.20e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.2","Tissue RNA - adrenal gland [nTPM]":"16.5","Tissue RNA - amygdala [nTPM]":"1.0","Tissue RNA - appendix [nTPM]":"11.4","Tissue RNA - basal ganglia [nTPM]":"0.7","Tissue RNA - bone marrow [nTPM]":"2.7","Tissue RNA - breast [nTPM]":"159.9","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"1.2","Tissue RNA - cervix [nTPM]":"32.2","Tissue RNA - choroid plexus [nTPM]":"8.7","Tissue RNA - colon [nTPM]":"60.9","Tissue RNA - duodenum [nTPM]":"152.2","Tissue RNA - endometrium 1 [nTPM]":"45.5","Tissue RNA - epididymis [nTPM]":"36.5","Tissue RNA - esophagus [nTPM]":"81.6","Tissue RNA - fallopian tube [nTPM]":"13.4","Tissue RNA - gallbladder [nTPM]":"24.9","Tissue RNA - heart muscle [nTPM]":"1.6","Tissue RNA - hippocampal formation [nTPM]":"1.2","Tissue RNA - hypothalamus [nTPM]":"2.8","Tissue RNA - kidney [nTPM]":"60.2","Tissue RNA - liver [nTPM]":"210.8","Tissue RNA - lung [nTPM]":"91.0","Tissue RNA - lymph node [nTPM]":"5.5","Tissue RNA - medulla oblongata [nTPM]":"1.4","Tissue RNA - midbrain [nTPM]":"2.0","Tissue RNA - ovary [nTPM]":"1.1","Tissue RNA - pancreas [nTPM]":"2.6","Tissue RNA - parathyroid gland [nTPM]":"85.3","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"99.1","Tissue RNA - pons [nTPM]":"1.0","Tissue RNA - prostate [nTPM]":"10.2","Tissue RNA - rectum [nTPM]":"57.4","Tissue RNA - retina [nTPM]":"1.0","Tissue RNA - salivary gland [nTPM]":"7.7","Tissue RNA - seminal vesicle [nTPM]":"4.0","Tissue RNA - skeletal muscle [nTPM]":"2.5","Tissue RNA - skin 1 [nTPM]":"39.8","Tissue RNA - small intestine [nTPM]":"117.3","Tissue RNA - smooth muscle [nTPM]":"63.7","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"10.3","Tissue RNA - stomach 1 [nTPM]":"235.0","Tissue RNA - testis [nTPM]":"1.6","Tissue RNA - thalamus [nTPM]":"2.2","Tissue RNA - thymus [nTPM]":"12.2","Tissue RNA - thyroid gland [nTPM]":"1.7","Tissue RNA - tongue [nTPM]":"3.0","Tissue RNA - tonsil [nTPM]":"26.6","Tissue RNA - urinary bladder [nTPM]":"376.0","Tissue RNA - vagina [nTPM]":"83.0","Tissue RNA - white matter [nTPM]":"0.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"157.8","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"110.6","Cell RNA - ASC TERT1 [nTPM]":"5.4","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"45.1","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"14.2","Cell RNA - HAP1 [nTPM]":"16.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"2.9","Cell RNA - HEL [nTPM]":"355.0","Cell RNA - HeLa [nTPM]":"10.8","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"2.1","Cell RNA - HMC-1 [nTPM]":"0.9","Cell RNA - HSkMC [nTPM]":"5.6","Cell RNA - hTCEpi [nTPM]":"2.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"22.6","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"1.2","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"1.4","Cell RNA - OE19 [nTPM]":"102.1","Cell RNA - PC-3 [nTPM]":"7.4","Cell RNA - REH [nTPM]":"16.3","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"1.3","Cell RNA - RPTEC TERT1 [nTPM]":"36.2","Cell RNA - RT4 [nTPM]":"565.7","Cell RNA - SCLC-21H [nTPM]":"0.9","Cell RNA - SH-SY5Y [nTPM]":"0.4","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"1.3","Cell RNA - SK-MEL-30 [nTPM]":"3.5","Cell RNA - SuSa [nTPM]":"121.3","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"28.4","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"123.7","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"16.6","Blood RNA - gdT-cell [nTPM]":"9.9","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"15.6","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"5.2","Blood RNA - memory CD8 T-cell [nTPM]":"4.5","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.6","Blood RNA - naive CD8 T-cell [nTPM]":"4.0","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"45.0","Blood RNA - total PBMC [nTPM]":"3.0","Brain RNA - amygdala [nTPM]":"1.0","Brain RNA - basal ganglia [nTPM]":"0.7","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"1.2","Brain RNA - hippocampal formation [nTPM]":"1.2","Brain RNA - hypothalamus [nTPM]":"2.8","Brain RNA - medulla oblongata [nTPM]":"1.4","Brain RNA - midbrain [nTPM]":"2.0","Brain RNA - pons [nTPM]":"1.0","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"2.2","Brain RNA - white matter [nTPM]":"0.7","Single Cell Type RNA - Adipocytes [nTPM]":"3.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"33.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"4.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"80.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"45.5","Single Cell Type RNA - Bipolar cells [nTPM]":"3.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"35.8","Single Cell Type RNA - Club cells [nTPM]":"23.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"48.5","Single Cell Type RNA - dendritic cells [nTPM]":"38.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"457.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"7.4","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.4","Single Cell Type RNA - Endothelial cells [nTPM]":"18.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"17.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"94.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"701.7","Single Cell Type RNA - Fibroblasts [nTPM]":"25.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"196.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"36.4","Single Cell Type RNA - granulocytes [nTPM]":"864.5","Single Cell Type RNA - Granulosa cells [nTPM]":"1.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.9","Single Cell Type RNA - Hepatocytes [nTPM]":"245.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"21.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"60.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"14.8","Single Cell Type RNA - Langerhans cells [nTPM]":"19.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"19.9","Single Cell Type RNA - Macrophages [nTPM]":"29.2","Single Cell Type RNA - Melanocytes [nTPM]":"76.5","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"2.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"42.4","Single Cell Type RNA - Paneth cells [nTPM]":"254.7","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"50.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"76.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"500.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"131.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"53.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"56.6","Single Cell Type RNA - T-cells [nTPM]":"42.7","Single Cell Type RNA - Theca cells [nTPM]":"65.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"58.9","Single Cell Type RNA - Urothelial cells [nTPM]":"922.8"},{"Gene":"HR","Gene synonym":["ALUNC","AU"],"Ensembl":"ENSG00000168453","Gene description":"HR lysine demethylase and nuclear receptor corepressor","Uniprot":["O43593"],"Chromosome":"8","Position":"22114419-22133384","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding","Oxidoreductase"],"Disease involvement":["Disease variant","Hypotrichosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"20.9","skin 1":"52.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"91.4","Cone photoreceptor cells":"33.3","Distal enterocytes":"27.5","Gastric mucus-secreting cells":"26.5","Paneth cells":"31.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"21.2","HaCaT":"81.7","OE19":"39.9","SiHa":"28.8","T-47d":"30.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054888"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA054888":"AB_2682630"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.00e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.4","Tissue RNA - adrenal gland [nTPM]":"1.0","Tissue RNA - amygdala [nTPM]":"4.3","Tissue RNA - appendix [nTPM]":"1.8","Tissue RNA - basal ganglia [nTPM]":"6.7","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"2.7","Tissue RNA - cerebellum [nTPM]":"7.8","Tissue RNA - cerebral cortex [nTPM]":"14.5","Tissue RNA - cervix [nTPM]":"3.8","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"9.0","Tissue RNA - duodenum [nTPM]":"4.8","Tissue RNA - endometrium 1 [nTPM]":"1.6","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"20.9","Tissue RNA - fallopian tube [nTPM]":"1.1","Tissue RNA - gallbladder [nTPM]":"1.3","Tissue RNA - heart muscle [nTPM]":"2.3","Tissue RNA - hippocampal formation [nTPM]":"3.1","Tissue RNA - hypothalamus [nTPM]":"4.8","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"0.8","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"11.3","Tissue RNA - midbrain [nTPM]":"9.0","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"0.5","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"2.7","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"12.0","Tissue RNA - prostate [nTPM]":"3.8","Tissue RNA - rectum [nTPM]":"3.2","Tissue RNA - retina [nTPM]":"1.8","Tissue RNA - salivary gland [nTPM]":"5.1","Tissue RNA - seminal vesicle [nTPM]":"4.2","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"52.7","Tissue RNA - small intestine [nTPM]":"4.7","Tissue RNA - smooth muscle [nTPM]":"1.5","Tissue RNA - spinal cord [nTPM]":"2.4","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"7.7","Tissue RNA - testis [nTPM]":"5.3","Tissue RNA - thalamus [nTPM]":"8.8","Tissue RNA - thymus [nTPM]":"0.6","Tissue RNA - thyroid gland [nTPM]":"4.3","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"1.2","Tissue RNA - urinary bladder [nTPM]":"3.0","Tissue RNA - vagina [nTPM]":"11.7","Tissue RNA - white matter [nTPM]":"11.5","Cell RNA - A-431 [nTPM]":"1.9","Cell RNA - A549 [nTPM]":"21.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.6","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"2.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"20.7","Cell RNA - fHDF\/TERT166 [nTPM]":"1.5","Cell RNA - GAMG [nTPM]":"1.0","Cell RNA - HaCaT [nTPM]":"81.7","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"2.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"17.8","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"4.7","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"4.1","Cell RNA - hTCEpi [nTPM]":"12.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"1.4","Cell RNA - hTERT-RPE1 [nTPM]":"1.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"2.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"12.7","Cell RNA - MOLT-4 [nTPM]":"1.5","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"39.9","Cell RNA - PC-3 [nTPM]":"16.3","Cell RNA - REH [nTPM]":"1.9","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.3","Cell RNA - RT4 [nTPM]":"5.7","Cell RNA - SCLC-21H [nTPM]":"1.0","Cell RNA - SH-SY5Y [nTPM]":"4.7","Cell RNA - SiHa [nTPM]":"28.8","Cell RNA - SK-BR-3 [nTPM]":"6.4","Cell RNA - SK-MEL-30 [nTPM]":"6.5","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"30.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.4","Cell RNA - U-2 OS [nTPM]":"17.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"7.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.3","Brain RNA - basal ganglia [nTPM]":"6.7","Brain RNA - cerebellum [nTPM]":"7.8","Brain RNA - cerebral cortex [nTPM]":"14.5","Brain RNA - hippocampal formation [nTPM]":"3.1","Brain RNA - hypothalamus [nTPM]":"4.8","Brain RNA - medulla oblongata [nTPM]":"11.3","Brain RNA - midbrain [nTPM]":"9.0","Brain RNA - pons [nTPM]":"12.0","Brain RNA - spinal cord [nTPM]":"2.4","Brain RNA - thalamus [nTPM]":"8.8","Brain RNA - white matter [nTPM]":"11.5","Single Cell Type RNA - Adipocytes [nTPM]":"1.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"91.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"27.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"2.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"26.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"2.1","Single Cell Type RNA - Late spermatids [nTPM]":"1.9","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"3.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"31.2","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.5","Single Cell Type RNA - Urothelial cells [nTPM]":"6.8"},{"Gene":"HRAS","Gene synonym":["HRAS1"],"Ensembl":"ENSG00000174775","Gene description":"HRas proto-oncogene, GTPase","Uniprot":["P01112"],"Chromosome":"11","Position":"532242-537287","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Suprabasal keratinocytes":"145.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"4.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002015","HPA049830","HPA070222"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB002015":null,"HPA049830":"AB_2680903","HPA070222":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.32e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Tissue RNA - adipose tissue [nTPM]":"28.1","Tissue RNA - adrenal gland [nTPM]":"24.6","Tissue RNA - amygdala [nTPM]":"64.6","Tissue RNA - appendix [nTPM]":"3.5","Tissue RNA - basal ganglia [nTPM]":"67.2","Tissue RNA - bone marrow [nTPM]":"2.9","Tissue RNA - breast [nTPM]":"27.0","Tissue RNA - cerebellum [nTPM]":"62.1","Tissue RNA - cerebral cortex [nTPM]":"86.8","Tissue RNA - cervix [nTPM]":"30.4","Tissue RNA - choroid plexus [nTPM]":"58.3","Tissue RNA - colon [nTPM]":"34.3","Tissue RNA - duodenum [nTPM]":"2.8","Tissue RNA - endometrium 1 [nTPM]":"23.6","Tissue RNA - epididymis [nTPM]":"12.5","Tissue RNA - esophagus [nTPM]":"80.1","Tissue RNA - fallopian tube [nTPM]":"18.9","Tissue RNA - gallbladder [nTPM]":"3.6","Tissue RNA - heart muscle [nTPM]":"56.8","Tissue RNA - hippocampal formation [nTPM]":"64.4","Tissue RNA - hypothalamus [nTPM]":"64.6","Tissue RNA - kidney [nTPM]":"33.8","Tissue RNA - liver [nTPM]":"21.8","Tissue RNA - lung [nTPM]":"27.1","Tissue RNA - lymph node [nTPM]":"4.3","Tissue RNA - medulla oblongata [nTPM]":"65.6","Tissue RNA - midbrain [nTPM]":"65.3","Tissue RNA - ovary [nTPM]":"20.0","Tissue RNA - pancreas [nTPM]":"20.5","Tissue RNA - parathyroid gland [nTPM]":"13.1","Tissue RNA - pituitary gland [nTPM]":"38.2","Tissue RNA - placenta [nTPM]":"9.0","Tissue RNA - pons [nTPM]":"66.9","Tissue RNA - prostate [nTPM]":"38.3","Tissue RNA - rectum [nTPM]":"6.9","Tissue RNA - retina [nTPM]":"10.2","Tissue RNA - salivary gland [nTPM]":"27.3","Tissue RNA - seminal vesicle [nTPM]":"12.3","Tissue RNA - skeletal muscle [nTPM]":"59.0","Tissue RNA - skin 1 [nTPM]":"69.9","Tissue RNA - small intestine [nTPM]":"19.5","Tissue RNA - smooth muscle [nTPM]":"8.9","Tissue RNA - spinal cord [nTPM]":"64.2","Tissue RNA - spleen [nTPM]":"20.6","Tissue RNA - stomach 1 [nTPM]":"24.2","Tissue RNA - testis [nTPM]":"16.5","Tissue RNA - thalamus [nTPM]":"64.8","Tissue RNA - thymus [nTPM]":"9.2","Tissue RNA - thyroid gland [nTPM]":"20.5","Tissue RNA - tongue [nTPM]":"25.2","Tissue RNA - tonsil [nTPM]":"10.2","Tissue RNA - urinary bladder [nTPM]":"34.5","Tissue RNA - vagina [nTPM]":"44.2","Tissue RNA - white matter [nTPM]":"65.4","Cell RNA - A-431 [nTPM]":"59.0","Cell RNA - A549 [nTPM]":"105.6","Cell RNA - AF22 [nTPM]":"44.2","Cell RNA - AN3-CA [nTPM]":"25.6","Cell RNA - ASC diff [nTPM]":"22.2","Cell RNA - ASC TERT1 [nTPM]":"17.5","Cell RNA - BEWO [nTPM]":"39.6","Cell RNA - BJ [nTPM]":"49.9","Cell RNA - BJ hTERT+ [nTPM]":"25.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"64.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"29.5","Cell RNA - CACO-2 [nTPM]":"62.4","Cell RNA - CAPAN-2 [nTPM]":"29.7","Cell RNA - Daudi [nTPM]":"20.4","Cell RNA - EFO-21 [nTPM]":"10.9","Cell RNA - fHDF\/TERT166 [nTPM]":"63.2","Cell RNA - GAMG [nTPM]":"60.7","Cell RNA - HaCaT [nTPM]":"43.7","Cell RNA - HAP1 [nTPM]":"46.0","Cell RNA - HBEC3-KT [nTPM]":"114.1","Cell RNA - HBF TERT88 [nTPM]":"19.3","Cell RNA - HDLM-2 [nTPM]":"19.5","Cell RNA - HEK 293 [nTPM]":"108.4","Cell RNA - HEL [nTPM]":"6.6","Cell RNA - HeLa [nTPM]":"43.7","Cell RNA - Hep G2 [nTPM]":"56.1","Cell RNA - HHSteC [nTPM]":"38.5","Cell RNA - HL-60 [nTPM]":"13.9","Cell RNA - HMC-1 [nTPM]":"12.0","Cell RNA - HSkMC [nTPM]":"28.3","Cell RNA - hTCEpi [nTPM]":"118.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"42.0","Cell RNA - hTERT-HME1 [nTPM]":"51.5","Cell RNA - hTERT-RPE1 [nTPM]":"19.6","Cell RNA - HUVEC TERT2 [nTPM]":"31.5","Cell RNA - JURKAT [nTPM]":"34.3","Cell RNA - K-562 [nTPM]":"29.7","Cell RNA - Karpas-707 [nTPM]":"32.3","Cell RNA - LHCN-M2 [nTPM]":"40.9","Cell RNA - MCF7 [nTPM]":"110.6","Cell RNA - MOLT-4 [nTPM]":"34.0","Cell RNA - NB-4 [nTPM]":"50.5","Cell RNA - NTERA-2 [nTPM]":"26.5","Cell RNA - OE19 [nTPM]":"39.9","Cell RNA - PC-3 [nTPM]":"94.5","Cell RNA - REH [nTPM]":"31.6","Cell RNA - RH-30 [nTPM]":"40.7","Cell RNA - RPMI-8226 [nTPM]":"18.2","Cell RNA - RPTEC TERT1 [nTPM]":"47.0","Cell RNA - RT4 [nTPM]":"33.2","Cell RNA - SCLC-21H [nTPM]":"87.6","Cell RNA - SH-SY5Y [nTPM]":"43.7","Cell RNA - SiHa [nTPM]":"25.5","Cell RNA - SK-BR-3 [nTPM]":"55.4","Cell RNA - SK-MEL-30 [nTPM]":"17.9","Cell RNA - SuSa [nTPM]":"31.5","Cell RNA - T-47d [nTPM]":"43.3","Cell RNA - THP-1 [nTPM]":"14.8","Cell RNA - TIME [nTPM]":"35.4","Cell RNA - U-138 MG [nTPM]":"47.3","Cell RNA - U-2 OS [nTPM]":"44.7","Cell RNA - U-2197 [nTPM]":"16.4","Cell RNA - U-251 MG [nTPM]":"39.7","Cell RNA - U-266\/70 [nTPM]":"20.3","Cell RNA - U-266\/84 [nTPM]":"17.7","Cell RNA - U-698 [nTPM]":"15.4","Cell RNA - U-87 MG [nTPM]":"39.1","Cell RNA - U-937 [nTPM]":"17.0","Cell RNA - WM-115 [nTPM]":"38.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"2.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.9","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"4.0","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"1.5","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"64.6","Brain RNA - basal ganglia [nTPM]":"67.2","Brain RNA - cerebellum [nTPM]":"62.1","Brain RNA - cerebral cortex [nTPM]":"86.8","Brain RNA - hippocampal formation [nTPM]":"64.4","Brain RNA - hypothalamus [nTPM]":"64.6","Brain RNA - medulla oblongata [nTPM]":"65.6","Brain RNA - midbrain [nTPM]":"65.3","Brain RNA - pons [nTPM]":"66.9","Brain RNA - spinal cord [nTPM]":"64.2","Brain RNA - thalamus [nTPM]":"64.8","Brain RNA - white matter [nTPM]":"65.4","Single Cell Type RNA - Adipocytes [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.7","Single Cell Type RNA - Astrocytes [nTPM]":"9.1","Single Cell Type RNA - B-cells [nTPM]":"18.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"131.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"101.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"25.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"82.0","Single Cell Type RNA - Bipolar cells [nTPM]":"46.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"38.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"75.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"11.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"35.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"78.8","Single Cell Type RNA - dendritic cells [nTPM]":"21.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"72.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"74.3","Single Cell Type RNA - Ductal cells [nTPM]":"35.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"36.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"28.6","Single Cell Type RNA - Endothelial cells [nTPM]":"32.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"29.3","Single Cell Type RNA - Erythroid cells [nTPM]":"11.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"37.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"63.4","Single Cell Type RNA - Fibroblasts [nTPM]":"25.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"33.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"34.1","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"26.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.9","Single Cell Type RNA - Hepatocytes [nTPM]":"17.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"39.9","Single Cell Type RNA - Horizontal cells [nTPM]":"48.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.5","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"11.7","Single Cell Type RNA - Langerhans cells [nTPM]":"38.4","Single Cell Type RNA - Late spermatids [nTPM]":"7.9","Single Cell Type RNA - Leydig cells [nTPM]":"17.1","Single Cell Type RNA - Macrophages [nTPM]":"21.3","Single Cell Type RNA - Melanocytes [nTPM]":"64.0","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"12.8","Single Cell Type RNA - Muller glia cells [nTPM]":"50.8","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"48.2","Single Cell Type RNA - Paneth cells [nTPM]":"30.9","Single Cell Type RNA - Peritubular cells [nTPM]":"23.0","Single Cell Type RNA - Plasma cells [nTPM]":"26.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"61.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"30.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"54.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"37.6","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"40.3","Single Cell Type RNA - Spermatocytes [nTPM]":"5.4","Single Cell Type RNA - Spermatogonia [nTPM]":"21.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"118.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"145.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"78.1","Single Cell Type RNA - T-cells [nTPM]":"22.0","Single Cell Type RNA - Theca cells [nTPM]":"18.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.2","Single Cell Type RNA - Urothelial cells [nTPM]":"106.4"},{"Gene":"HSD17B3","Gene synonym":["SDR12C2"],"Ensembl":"ENSG00000130948","Gene description":"Hydroxysteroid 17-beta dehydrogenase 3","Uniprot":["P37058"],"Chromosome":"9","Position":"96235306-96302176","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Pseudohermaphroditism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"15.1","testis":"36.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Leydig cells":"108.1","Oligodendrocytes":"93.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HBEC3-KT":"2.3","HEL":"1.0","U-2 OS":"4.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056833"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 9: U-2 OS - Unknown function","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA056833":"AB_2683252"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.47e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.6","Tissue RNA - adrenal gland [nTPM]":"0.8","Tissue RNA - amygdala [nTPM]":"3.1","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"4.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.7","Tissue RNA - cerebellum [nTPM]":"3.4","Tissue RNA - cerebral cortex [nTPM]":"5.9","Tissue RNA - cervix [nTPM]":"3.1","Tissue RNA - choroid plexus [nTPM]":"2.4","Tissue RNA - colon [nTPM]":"2.7","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"1.5","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"0.7","Tissue RNA - fallopian tube [nTPM]":"3.5","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"2.1","Tissue RNA - hippocampal formation [nTPM]":"3.1","Tissue RNA - hypothalamus [nTPM]":"3.6","Tissue RNA - kidney [nTPM]":"4.7","Tissue RNA - liver [nTPM]":"15.1","Tissue RNA - lung [nTPM]":"1.8","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"4.3","Tissue RNA - midbrain [nTPM]":"3.9","Tissue RNA - ovary [nTPM]":"1.4","Tissue RNA - pancreas [nTPM]":"4.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.7","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"4.2","Tissue RNA - prostate [nTPM]":"3.2","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.7","Tissue RNA - salivary gland [nTPM]":"1.0","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"3.7","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"3.3","Tissue RNA - spleen [nTPM]":"0.9","Tissue RNA - stomach 1 [nTPM]":"1.4","Tissue RNA - testis [nTPM]":"36.7","Tissue RNA - thalamus [nTPM]":"4.2","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"10.0","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"1.6","Tissue RNA - vagina [nTPM]":"1.8","Tissue RNA - white matter [nTPM]":"5.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"2.3","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"1.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.7","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"4.4","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"3.1","Brain RNA - basal ganglia [nTPM]":"4.3","Brain RNA - cerebellum [nTPM]":"3.4","Brain RNA - cerebral cortex [nTPM]":"5.9","Brain RNA - hippocampal formation [nTPM]":"3.1","Brain RNA - hypothalamus [nTPM]":"3.6","Brain RNA - medulla oblongata [nTPM]":"4.3","Brain RNA - midbrain [nTPM]":"3.9","Brain RNA - pons [nTPM]":"4.2","Brain RNA - spinal cord [nTPM]":"3.3","Brain RNA - thalamus [nTPM]":"4.2","Brain RNA - white matter [nTPM]":"5.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"15.3","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"4.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"2.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"14.4","Single Cell Type RNA - Leydig cells [nTPM]":"108.1","Single Cell Type RNA - Macrophages [nTPM]":"1.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"93.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"12.8","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"1.9","Single Cell Type RNA - Spermatogonia [nTPM]":"1.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"HSD17B4","Gene synonym":["DBP","MFE-2","SDR8C1"],"Ensembl":"ENSG00000133835","Gene description":"Hydroxysteroid 17-beta dehydrogenase 4","Uniprot":["P51659"],"Chromosome":"5","Position":"119452473-119637199","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Isomerase","Lyase","Oxidoreductase"],"Disease involvement":["Deafness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"320.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"225.1","Oligodendrocytes":"221.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"75.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021302","HPA021311","HPA021479"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Peroxisomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"450000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Peroxisomes"],"Subcellular additional location":null,"Antibody RRID":{"HPA021302":"AB_1844350","HPA021311":"AB_1844351","HPA021479":"AB_1844352"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.33e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.31e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-3"},"Tissue RNA - adipose tissue [nTPM]":"74.4","Tissue RNA - adrenal gland [nTPM]":"85.0","Tissue RNA - amygdala [nTPM]":"37.2","Tissue RNA - appendix [nTPM]":"41.9","Tissue RNA - basal ganglia [nTPM]":"50.2","Tissue RNA - bone marrow [nTPM]":"19.7","Tissue RNA - breast [nTPM]":"44.4","Tissue RNA - cerebellum [nTPM]":"51.1","Tissue RNA - cerebral cortex [nTPM]":"50.0","Tissue RNA - cervix [nTPM]":"68.8","Tissue RNA - choroid plexus [nTPM]":"47.2","Tissue RNA - colon [nTPM]":"64.5","Tissue RNA - duodenum [nTPM]":"79.3","Tissue RNA - endometrium 1 [nTPM]":"34.1","Tissue RNA - epididymis [nTPM]":"53.0","Tissue RNA - esophagus [nTPM]":"50.9","Tissue RNA - fallopian tube [nTPM]":"39.1","Tissue RNA - gallbladder [nTPM]":"52.5","Tissue RNA - heart muscle [nTPM]":"68.6","Tissue RNA - hippocampal formation [nTPM]":"34.9","Tissue RNA - hypothalamus [nTPM]":"50.7","Tissue RNA - kidney [nTPM]":"84.4","Tissue RNA - liver [nTPM]":"320.0","Tissue RNA - lung [nTPM]":"75.6","Tissue RNA - lymph node [nTPM]":"33.2","Tissue RNA - medulla oblongata [nTPM]":"50.6","Tissue RNA - midbrain [nTPM]":"49.5","Tissue RNA - ovary [nTPM]":"34.8","Tissue RNA - pancreas [nTPM]":"55.2","Tissue RNA - parathyroid gland [nTPM]":"75.5","Tissue RNA - pituitary gland [nTPM]":"26.5","Tissue RNA - placenta [nTPM]":"53.4","Tissue RNA - pons [nTPM]":"49.2","Tissue RNA - prostate [nTPM]":"56.8","Tissue RNA - rectum [nTPM]":"65.9","Tissue RNA - retina [nTPM]":"27.2","Tissue RNA - salivary gland [nTPM]":"44.9","Tissue RNA - seminal vesicle [nTPM]":"79.0","Tissue RNA - skeletal muscle [nTPM]":"59.8","Tissue RNA - skin 1 [nTPM]":"51.8","Tissue RNA - small intestine [nTPM]":"87.6","Tissue RNA - smooth muscle [nTPM]":"39.5","Tissue RNA - spinal cord [nTPM]":"44.7","Tissue RNA - spleen [nTPM]":"36.6","Tissue RNA - stomach 1 [nTPM]":"53.8","Tissue RNA - testis [nTPM]":"20.9","Tissue RNA - thalamus [nTPM]":"49.9","Tissue RNA - thymus [nTPM]":"31.9","Tissue RNA - thyroid gland [nTPM]":"133.9","Tissue RNA - tongue [nTPM]":"52.8","Tissue RNA - tonsil [nTPM]":"39.7","Tissue RNA - urinary bladder [nTPM]":"57.7","Tissue RNA - vagina [nTPM]":"31.5","Tissue RNA - white matter [nTPM]":"56.3","Cell RNA - A-431 [nTPM]":"68.8","Cell RNA - A549 [nTPM]":"59.8","Cell RNA - AF22 [nTPM]":"104.1","Cell RNA - AN3-CA [nTPM]":"143.7","Cell RNA - ASC diff [nTPM]":"261.8","Cell RNA - ASC TERT1 [nTPM]":"120.3","Cell RNA - BEWO [nTPM]":"57.9","Cell RNA - BJ [nTPM]":"63.4","Cell RNA - BJ hTERT+ [nTPM]":"80.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"57.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"103.0","Cell RNA - CACO-2 [nTPM]":"49.4","Cell RNA - CAPAN-2 [nTPM]":"112.8","Cell RNA - Daudi [nTPM]":"84.4","Cell RNA - EFO-21 [nTPM]":"128.0","Cell RNA - fHDF\/TERT166 [nTPM]":"70.6","Cell RNA - GAMG [nTPM]":"81.0","Cell RNA - HaCaT [nTPM]":"68.7","Cell RNA - HAP1 [nTPM]":"77.0","Cell RNA - HBEC3-KT [nTPM]":"144.4","Cell RNA - HBF TERT88 [nTPM]":"84.3","Cell RNA - HDLM-2 [nTPM]":"94.6","Cell RNA - HEK 293 [nTPM]":"79.8","Cell RNA - HEL [nTPM]":"118.1","Cell RNA - HeLa [nTPM]":"62.0","Cell RNA - Hep G2 [nTPM]":"96.9","Cell RNA - HHSteC [nTPM]":"65.8","Cell RNA - HL-60 [nTPM]":"38.0","Cell RNA - HMC-1 [nTPM]":"169.9","Cell RNA - HSkMC [nTPM]":"110.0","Cell RNA - hTCEpi [nTPM]":"56.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"64.9","Cell RNA - hTERT-HME1 [nTPM]":"54.7","Cell RNA - hTERT-RPE1 [nTPM]":"69.3","Cell RNA - HUVEC TERT2 [nTPM]":"103.9","Cell RNA - JURKAT [nTPM]":"59.4","Cell RNA - K-562 [nTPM]":"41.0","Cell RNA - Karpas-707 [nTPM]":"48.9","Cell RNA - LHCN-M2 [nTPM]":"64.2","Cell RNA - MCF7 [nTPM]":"64.0","Cell RNA - MOLT-4 [nTPM]":"59.2","Cell RNA - NB-4 [nTPM]":"23.6","Cell RNA - NTERA-2 [nTPM]":"82.1","Cell RNA - OE19 [nTPM]":"161.1","Cell RNA - PC-3 [nTPM]":"43.1","Cell RNA - REH [nTPM]":"68.7","Cell RNA - RH-30 [nTPM]":"103.0","Cell RNA - RPMI-8226 [nTPM]":"104.8","Cell RNA - RPTEC TERT1 [nTPM]":"92.2","Cell RNA - RT4 [nTPM]":"192.7","Cell RNA - SCLC-21H [nTPM]":"81.1","Cell RNA - SH-SY5Y [nTPM]":"70.6","Cell RNA - SiHa [nTPM]":"149.0","Cell RNA - SK-BR-3 [nTPM]":"23.4","Cell RNA - SK-MEL-30 [nTPM]":"78.7","Cell RNA - SuSa [nTPM]":"93.3","Cell RNA - T-47d [nTPM]":"88.7","Cell RNA - THP-1 [nTPM]":"68.2","Cell RNA - TIME [nTPM]":"67.6","Cell RNA - U-138 MG [nTPM]":"52.7","Cell RNA - U-2 OS [nTPM]":"38.1","Cell RNA - U-2197 [nTPM]":"66.5","Cell RNA - U-251 MG [nTPM]":"53.1","Cell RNA - U-266\/70 [nTPM]":"26.3","Cell RNA - U-266\/84 [nTPM]":"55.3","Cell RNA - U-698 [nTPM]":"32.6","Cell RNA - U-87 MG [nTPM]":"63.7","Cell RNA - U-937 [nTPM]":"104.4","Cell RNA - WM-115 [nTPM]":"56.7","Blood RNA - basophil [nTPM]":"75.5","Blood RNA - classical monocyte [nTPM]":"27.3","Blood RNA - eosinophil [nTPM]":"49.9","Blood RNA - gdT-cell [nTPM]":"6.5","Blood RNA - intermediate monocyte [nTPM]":"15.5","Blood RNA - MAIT T-cell [nTPM]":"7.3","Blood RNA - memory B-cell [nTPM]":"11.1","Blood RNA - memory CD4 T-cell [nTPM]":"5.8","Blood RNA - memory CD8 T-cell [nTPM]":"5.3","Blood RNA - myeloid DC [nTPM]":"21.3","Blood RNA - naive B-cell [nTPM]":"10.3","Blood RNA - naive CD4 T-cell [nTPM]":"5.5","Blood RNA - naive CD8 T-cell [nTPM]":"5.2","Blood RNA - neutrophil [nTPM]":"4.9","Blood RNA - NK-cell [nTPM]":"6.9","Blood RNA - non-classical monocyte [nTPM]":"17.1","Blood RNA - plasmacytoid DC [nTPM]":"13.8","Blood RNA - T-reg [nTPM]":"4.1","Blood RNA - total PBMC [nTPM]":"12.2","Brain RNA - amygdala [nTPM]":"37.2","Brain RNA - basal ganglia [nTPM]":"50.2","Brain RNA - cerebellum [nTPM]":"51.1","Brain RNA - cerebral cortex [nTPM]":"50.0","Brain RNA - hippocampal formation [nTPM]":"34.9","Brain RNA - hypothalamus [nTPM]":"50.7","Brain RNA - medulla oblongata [nTPM]":"50.6","Brain RNA - midbrain [nTPM]":"49.5","Brain RNA - pons [nTPM]":"49.2","Brain RNA - spinal cord [nTPM]":"44.7","Brain RNA - thalamus [nTPM]":"49.9","Brain RNA - white matter [nTPM]":"56.3","Single Cell Type RNA - Adipocytes [nTPM]":"38.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"73.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"125.2","Single Cell Type RNA - Astrocytes [nTPM]":"47.3","Single Cell Type RNA - B-cells [nTPM]":"28.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"42.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"43.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"19.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"31.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"22.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"76.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"64.3","Single Cell Type RNA - Club cells [nTPM]":"52.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"64.3","Single Cell Type RNA - dendritic cells [nTPM]":"19.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"40.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"84.1","Single Cell Type RNA - Ductal cells [nTPM]":"39.9","Single Cell Type RNA - Early spermatids [nTPM]":"8.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"29.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"48.9","Single Cell Type RNA - Endothelial cells [nTPM]":"32.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"33.0","Single Cell Type RNA - Erythroid cells [nTPM]":"42.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"92.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"35.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"29.3","Single Cell Type RNA - Fibroblasts [nTPM]":"35.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"48.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"35.8","Single Cell Type RNA - granulocytes [nTPM]":"68.4","Single Cell Type RNA - Granulosa cells [nTPM]":"25.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.2","Single Cell Type RNA - Hepatocytes [nTPM]":"225.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"77.9","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"102.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"45.8","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"51.8","Single Cell Type RNA - Langerhans cells [nTPM]":"13.8","Single Cell Type RNA - Late spermatids [nTPM]":"13.4","Single Cell Type RNA - Leydig cells [nTPM]":"34.5","Single Cell Type RNA - Macrophages [nTPM]":"46.7","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"49.6","Single Cell Type RNA - monocytes [nTPM]":"85.7","Single Cell Type RNA - Muller glia cells [nTPM]":"47.3","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"78.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"221.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.5","Single Cell Type RNA - Paneth cells [nTPM]":"29.6","Single Cell Type RNA - Peritubular cells [nTPM]":"51.1","Single Cell Type RNA - Plasma cells [nTPM]":"23.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"24.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"85.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"65.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"29.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.2","Single Cell Type RNA - Spermatocytes [nTPM]":"30.6","Single Cell Type RNA - Spermatogonia [nTPM]":"22.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"34.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"65.0","Single Cell Type RNA - T-cells [nTPM]":"15.7","Single Cell Type RNA - Theca cells [nTPM]":"57.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"55.3","Single Cell Type RNA - Urothelial cells [nTPM]":"39.7"},{"Gene":"HSD3B7","Gene synonym":["C(27)-3BETA-HSD","SDR11E3"],"Ensembl":"ENSG00000099377","Gene description":"Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7","Uniprot":["Q9H2F3"],"Chromosome":"16","Position":"30985207-30989147","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Steroidogenesis"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Intrahepatic cholestasis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"liver":"136.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"42.5","Hepatocytes":"68.9","Hofbauer cells":"53.9","Proximal enterocytes":"45.3","Proximal tubular cells":"46.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"27","RNA blood cell specific nTPM":{"basophil":"61.8","eosinophil":"27.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"38","RNA blood lineage specific nTPM":{"granulocytes":"61.8"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"91.0","Hep G2":"66.2","HMC-1":"98.1","U-2197":"96.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015965","HPA050521","HPA060847"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Lipid droplets"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Lipid droplets"],"Subcellular additional location":null,"Antibody RRID":{"HPA015965":null,"HPA050521":"AB_2681155","HPA060847":"AB_2684379"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.95e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.60e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Tissue RNA - adipose tissue [nTPM]":"27.3","Tissue RNA - adrenal gland [nTPM]":"25.7","Tissue RNA - amygdala [nTPM]":"5.7","Tissue RNA - appendix [nTPM]":"10.9","Tissue RNA - basal ganglia [nTPM]":"6.2","Tissue RNA - bone marrow [nTPM]":"4.4","Tissue RNA - breast [nTPM]":"17.1","Tissue RNA - cerebellum [nTPM]":"14.7","Tissue RNA - cerebral cortex [nTPM]":"9.1","Tissue RNA - cervix [nTPM]":"8.5","Tissue RNA - choroid plexus [nTPM]":"3.5","Tissue RNA - colon [nTPM]":"15.9","Tissue RNA - duodenum [nTPM]":"19.5","Tissue RNA - endometrium 1 [nTPM]":"9.5","Tissue RNA - epididymis [nTPM]":"2.1","Tissue RNA - esophagus [nTPM]":"12.3","Tissue RNA - fallopian tube [nTPM]":"9.4","Tissue RNA - gallbladder [nTPM]":"11.5","Tissue RNA - heart muscle [nTPM]":"11.7","Tissue RNA - hippocampal formation [nTPM]":"5.9","Tissue RNA - hypothalamus [nTPM]":"5.9","Tissue RNA - kidney [nTPM]":"27.7","Tissue RNA - liver [nTPM]":"136.5","Tissue RNA - lung [nTPM]":"11.2","Tissue RNA - lymph node [nTPM]":"8.4","Tissue RNA - medulla oblongata [nTPM]":"6.3","Tissue RNA - midbrain [nTPM]":"5.4","Tissue RNA - ovary [nTPM]":"8.6","Tissue RNA - pancreas [nTPM]":"25.6","Tissue RNA - parathyroid gland [nTPM]":"8.0","Tissue RNA - pituitary gland [nTPM]":"5.4","Tissue RNA - placenta [nTPM]":"4.5","Tissue RNA - pons [nTPM]":"6.6","Tissue RNA - prostate [nTPM]":"8.2","Tissue RNA - rectum [nTPM]":"5.8","Tissue RNA - retina [nTPM]":"1.6","Tissue RNA - salivary gland [nTPM]":"10.0","Tissue RNA - seminal vesicle [nTPM]":"4.5","Tissue RNA - skeletal muscle [nTPM]":"7.0","Tissue RNA - skin 1 [nTPM]":"18.5","Tissue RNA - small intestine [nTPM]":"18.4","Tissue RNA - smooth muscle [nTPM]":"9.8","Tissue RNA - spinal cord [nTPM]":"5.6","Tissue RNA - spleen [nTPM]":"16.3","Tissue RNA - stomach 1 [nTPM]":"11.1","Tissue RNA - testis [nTPM]":"6.0","Tissue RNA - thalamus [nTPM]":"7.1","Tissue RNA - thymus [nTPM]":"2.8","Tissue RNA - thyroid gland [nTPM]":"6.3","Tissue RNA - tongue [nTPM]":"4.5","Tissue RNA - tonsil [nTPM]":"5.5","Tissue RNA - urinary bladder [nTPM]":"13.9","Tissue RNA - vagina [nTPM]":"8.7","Tissue RNA - white matter [nTPM]":"6.9","Cell RNA - A-431 [nTPM]":"20.3","Cell RNA - A549 [nTPM]":"23.2","Cell RNA - AF22 [nTPM]":"2.4","Cell RNA - AN3-CA [nTPM]":"11.5","Cell RNA - ASC diff [nTPM]":"7.9","Cell RNA - ASC TERT1 [nTPM]":"28.5","Cell RNA - BEWO [nTPM]":"1.4","Cell RNA - BJ [nTPM]":"24.8","Cell RNA - BJ hTERT+ [nTPM]":"38.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.0","Cell RNA - CACO-2 [nTPM]":"1.7","Cell RNA - CAPAN-2 [nTPM]":"34.4","Cell RNA - Daudi [nTPM]":"1.2","Cell RNA - EFO-21 [nTPM]":"8.1","Cell RNA - fHDF\/TERT166 [nTPM]":"30.3","Cell RNA - GAMG [nTPM]":"0.8","Cell RNA - HaCaT [nTPM]":"6.1","Cell RNA - HAP1 [nTPM]":"2.2","Cell RNA - HBEC3-KT [nTPM]":"3.6","Cell RNA - HBF TERT88 [nTPM]":"2.4","Cell RNA - HDLM-2 [nTPM]":"91.0","Cell RNA - HEK 293 [nTPM]":"5.4","Cell RNA - HEL [nTPM]":"1.6","Cell RNA - HeLa [nTPM]":"18.6","Cell RNA - Hep G2 [nTPM]":"66.2","Cell RNA - HHSteC [nTPM]":"7.4","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"98.1","Cell RNA - HSkMC [nTPM]":"13.7","Cell RNA - hTCEpi [nTPM]":"6.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"23.1","Cell RNA - hTERT-HME1 [nTPM]":"4.6","Cell RNA - hTERT-RPE1 [nTPM]":"11.2","Cell RNA - HUVEC TERT2 [nTPM]":"2.2","Cell RNA - JURKAT [nTPM]":"1.2","Cell RNA - K-562 [nTPM]":"4.9","Cell RNA - Karpas-707 [nTPM]":"1.0","Cell RNA - LHCN-M2 [nTPM]":"18.3","Cell RNA - MCF7 [nTPM]":"43.6","Cell RNA - MOLT-4 [nTPM]":"0.6","Cell RNA - NB-4 [nTPM]":"14.4","Cell RNA - NTERA-2 [nTPM]":"1.9","Cell RNA - OE19 [nTPM]":"8.5","Cell RNA - PC-3 [nTPM]":"3.2","Cell RNA - REH [nTPM]":"2.5","Cell RNA - RH-30 [nTPM]":"7.8","Cell RNA - RPMI-8226 [nTPM]":"22.3","Cell RNA - RPTEC TERT1 [nTPM]":"15.1","Cell RNA - RT4 [nTPM]":"1.3","Cell RNA - SCLC-21H [nTPM]":"8.4","Cell RNA - SH-SY5Y [nTPM]":"4.1","Cell RNA - SiHa [nTPM]":"3.2","Cell RNA - SK-BR-3 [nTPM]":"15.9","Cell RNA - SK-MEL-30 [nTPM]":"2.2","Cell RNA - SuSa [nTPM]":"1.1","Cell RNA - T-47d [nTPM]":"31.1","Cell RNA - THP-1 [nTPM]":"1.6","Cell RNA - TIME [nTPM]":"11.5","Cell RNA - U-138 MG [nTPM]":"10.0","Cell RNA - U-2 OS [nTPM]":"2.8","Cell RNA - U-2197 [nTPM]":"96.1","Cell RNA - U-251 MG [nTPM]":"2.7","Cell RNA - U-266\/70 [nTPM]":"1.6","Cell RNA - U-266\/84 [nTPM]":"15.4","Cell RNA - U-698 [nTPM]":"1.1","Cell RNA - U-87 MG [nTPM]":"39.1","Cell RNA - U-937 [nTPM]":"2.5","Cell RNA - WM-115 [nTPM]":"0.8","Blood RNA - basophil [nTPM]":"61.8","Blood RNA - classical monocyte [nTPM]":"1.4","Blood RNA - eosinophil [nTPM]":"27.3","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"1.6","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"1.2","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"5.7","Brain RNA - basal ganglia [nTPM]":"6.2","Brain RNA - cerebellum [nTPM]":"14.7","Brain RNA - cerebral cortex [nTPM]":"9.1","Brain RNA - hippocampal formation [nTPM]":"5.9","Brain RNA - hypothalamus [nTPM]":"5.9","Brain RNA - medulla oblongata [nTPM]":"6.3","Brain RNA - midbrain [nTPM]":"5.4","Brain RNA - pons [nTPM]":"6.6","Brain RNA - spinal cord [nTPM]":"5.6","Brain RNA - thalamus [nTPM]":"7.1","Brain RNA - white matter [nTPM]":"6.9","Single Cell Type RNA - Adipocytes [nTPM]":"7.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.2","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"1.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"2.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"42.5","Single Cell Type RNA - Early spermatids [nTPM]":"37.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.1","Single Cell Type RNA - Endothelial cells [nTPM]":"11.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.8","Single Cell Type RNA - Erythroid cells [nTPM]":"4.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.5","Single Cell Type RNA - Fibroblasts [nTPM]":"26.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.2","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"9.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"68.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"53.9","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.4","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"7.3","Single Cell Type RNA - Langerhans cells [nTPM]":"15.9","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"11.4","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"12.8","Single Cell Type RNA - Muller glia cells [nTPM]":"2.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.7","Single Cell Type RNA - Paneth cells [nTPM]":"14.0","Single Cell Type RNA - Peritubular cells [nTPM]":"5.3","Single Cell Type RNA - Plasma cells [nTPM]":"1.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"45.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"46.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - T-cells [nTPM]":"1.7","Single Cell Type RNA - Theca cells [nTPM]":"6.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.5","Single Cell Type RNA - Urothelial cells [nTPM]":"2.8"},{"Gene":"HSPA5","Gene synonym":["BiP","GRP78"],"Ensembl":"ENSG00000044574","Gene description":"Heat shock protein family A (Hsp70) member 5","Uniprot":["P11021"],"Chromosome":"9","Position":"125234853-125241382","Protein class":["Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":["Chaperone","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"1327.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005221","HPA038845","HPA038846"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"790000000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB005221":"AB_631616","HPA038845":"AB_10673477","HPA038846":"AB_10673478"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.60e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.05e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Tissue RNA - adipose tissue [nTPM]":"211.2","Tissue RNA - adrenal gland [nTPM]":"170.2","Tissue RNA - amygdala [nTPM]":"83.7","Tissue RNA - appendix [nTPM]":"276.1","Tissue RNA - basal ganglia [nTPM]":"91.7","Tissue RNA - bone marrow [nTPM]":"856.2","Tissue RNA - breast [nTPM]":"147.2","Tissue RNA - cerebellum [nTPM]":"101.8","Tissue RNA - cerebral cortex [nTPM]":"107.3","Tissue RNA - cervix [nTPM]":"202.9","Tissue RNA - choroid plexus [nTPM]":"112.0","Tissue RNA - colon [nTPM]":"181.6","Tissue RNA - duodenum [nTPM]":"166.5","Tissue RNA - endometrium 1 [nTPM]":"183.6","Tissue RNA - epididymis [nTPM]":"379.1","Tissue RNA - esophagus [nTPM]":"150.7","Tissue RNA - fallopian tube [nTPM]":"177.9","Tissue RNA - gallbladder [nTPM]":"130.6","Tissue RNA - heart muscle [nTPM]":"284.0","Tissue RNA - hippocampal formation [nTPM]":"90.2","Tissue RNA - hypothalamus [nTPM]":"126.8","Tissue RNA - kidney [nTPM]":"168.7","Tissue RNA - liver [nTPM]":"327.8","Tissue RNA - lung [nTPM]":"182.8","Tissue RNA - lymph node [nTPM]":"145.4","Tissue RNA - medulla oblongata [nTPM]":"105.8","Tissue RNA - midbrain [nTPM]":"107.0","Tissue RNA - ovary [nTPM]":"142.1","Tissue RNA - pancreas [nTPM]":"260.7","Tissue RNA - parathyroid gland [nTPM]":"223.3","Tissue RNA - pituitary gland [nTPM]":"182.7","Tissue RNA - placenta [nTPM]":"311.3","Tissue RNA - pons [nTPM]":"120.2","Tissue RNA - prostate [nTPM]":"192.8","Tissue RNA - rectum [nTPM]":"183.7","Tissue RNA - retina [nTPM]":"105.1","Tissue RNA - salivary gland [nTPM]":"211.0","Tissue RNA - seminal vesicle [nTPM]":"167.5","Tissue RNA - skeletal muscle [nTPM]":"87.6","Tissue RNA - skin 1 [nTPM]":"143.2","Tissue RNA - small intestine [nTPM]":"175.8","Tissue RNA - smooth muscle [nTPM]":"205.2","Tissue RNA - spinal cord [nTPM]":"111.4","Tissue RNA - spleen [nTPM]":"129.8","Tissue RNA - stomach 1 [nTPM]":"177.9","Tissue RNA - testis [nTPM]":"173.5","Tissue RNA - thalamus [nTPM]":"101.7","Tissue RNA - thymus [nTPM]":"116.2","Tissue RNA - thyroid gland [nTPM]":"692.8","Tissue RNA - tongue [nTPM]":"85.2","Tissue RNA - tonsil [nTPM]":"180.0","Tissue RNA - urinary bladder [nTPM]":"197.7","Tissue RNA - vagina [nTPM]":"105.1","Tissue RNA - white matter [nTPM]":"163.9","Cell RNA - A-431 [nTPM]":"593.4","Cell RNA - A549 [nTPM]":"380.3","Cell RNA - AF22 [nTPM]":"480.2","Cell RNA - AN3-CA [nTPM]":"631.3","Cell RNA - ASC diff [nTPM]":"505.6","Cell RNA - ASC TERT1 [nTPM]":"592.0","Cell RNA - BEWO [nTPM]":"1152.8","Cell RNA - BJ [nTPM]":"1047.6","Cell RNA - BJ hTERT+ [nTPM]":"728.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"675.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"778.5","Cell RNA - CACO-2 [nTPM]":"558.4","Cell RNA - CAPAN-2 [nTPM]":"1093.4","Cell RNA - Daudi [nTPM]":"649.5","Cell RNA - EFO-21 [nTPM]":"644.7","Cell RNA - fHDF\/TERT166 [nTPM]":"682.4","Cell RNA - GAMG [nTPM]":"1564.0","Cell RNA - HaCaT [nTPM]":"732.5","Cell RNA - HAP1 [nTPM]":"403.3","Cell RNA - HBEC3-KT [nTPM]":"839.4","Cell RNA - HBF TERT88 [nTPM]":"684.7","Cell RNA - HDLM-2 [nTPM]":"403.7","Cell RNA - HEK 293 [nTPM]":"213.8","Cell RNA - HEL [nTPM]":"396.7","Cell RNA - HeLa [nTPM]":"392.9","Cell RNA - Hep G2 [nTPM]":"945.1","Cell RNA - HHSteC [nTPM]":"2692.4","Cell RNA - HL-60 [nTPM]":"547.4","Cell RNA - HMC-1 [nTPM]":"730.2","Cell RNA - HSkMC [nTPM]":"363.6","Cell RNA - hTCEpi [nTPM]":"1515.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"551.3","Cell RNA - hTERT-HME1 [nTPM]":"2309.4","Cell RNA - hTERT-RPE1 [nTPM]":"728.1","Cell RNA - HUVEC TERT2 [nTPM]":"1065.6","Cell RNA - JURKAT [nTPM]":"129.0","Cell RNA - K-562 [nTPM]":"291.9","Cell RNA - Karpas-707 [nTPM]":"870.3","Cell RNA - LHCN-M2 [nTPM]":"482.2","Cell RNA - MCF7 [nTPM]":"382.6","Cell RNA - MOLT-4 [nTPM]":"249.7","Cell RNA - NB-4 [nTPM]":"297.8","Cell RNA - NTERA-2 [nTPM]":"559.1","Cell RNA - OE19 [nTPM]":"1327.5","Cell RNA - PC-3 [nTPM]":"362.2","Cell RNA - REH [nTPM]":"233.2","Cell RNA - RH-30 [nTPM]":"492.4","Cell RNA - RPMI-8226 [nTPM]":"1061.2","Cell RNA - RPTEC TERT1 [nTPM]":"608.4","Cell RNA - RT4 [nTPM]":"352.7","Cell RNA - SCLC-21H [nTPM]":"248.5","Cell RNA - SH-SY5Y [nTPM]":"448.0","Cell RNA - SiHa [nTPM]":"648.1","Cell RNA - SK-BR-3 [nTPM]":"653.4","Cell RNA - SK-MEL-30 [nTPM]":"1079.3","Cell RNA - SuSa [nTPM]":"715.5","Cell RNA - T-47d [nTPM]":"694.3","Cell RNA - THP-1 [nTPM]":"378.0","Cell RNA - TIME [nTPM]":"791.8","Cell RNA - U-138 MG [nTPM]":"439.5","Cell RNA - U-2 OS [nTPM]":"433.0","Cell RNA - U-2197 [nTPM]":"462.7","Cell RNA - U-251 MG [nTPM]":"484.2","Cell RNA - U-266\/70 [nTPM]":"939.0","Cell RNA - U-266\/84 [nTPM]":"994.7","Cell RNA - U-698 [nTPM]":"551.2","Cell RNA - U-87 MG [nTPM]":"1070.4","Cell RNA - U-937 [nTPM]":"435.9","Cell RNA - WM-115 [nTPM]":"689.0","Blood RNA - basophil [nTPM]":"455.5","Blood RNA - classical monocyte [nTPM]":"366.3","Blood RNA - eosinophil [nTPM]":"305.3","Blood RNA - gdT-cell [nTPM]":"384.7","Blood RNA - intermediate monocyte [nTPM]":"361.8","Blood RNA - MAIT T-cell [nTPM]":"390.0","Blood RNA - memory B-cell [nTPM]":"209.0","Blood RNA - memory CD4 T-cell [nTPM]":"276.7","Blood RNA - memory CD8 T-cell [nTPM]":"360.1","Blood RNA - myeloid DC [nTPM]":"322.0","Blood RNA - naive B-cell [nTPM]":"173.9","Blood RNA - naive CD4 T-cell [nTPM]":"224.6","Blood RNA - naive CD8 T-cell [nTPM]":"277.2","Blood RNA - neutrophil [nTPM]":"280.9","Blood RNA - NK-cell [nTPM]":"362.9","Blood RNA - non-classical monocyte [nTPM]":"252.5","Blood RNA - plasmacytoid DC [nTPM]":"349.5","Blood RNA - T-reg [nTPM]":"213.6","Blood RNA - total PBMC [nTPM]":"758.2","Brain RNA - amygdala [nTPM]":"83.7","Brain RNA - basal ganglia [nTPM]":"91.7","Brain RNA - cerebellum [nTPM]":"101.8","Brain RNA - cerebral cortex [nTPM]":"107.3","Brain RNA - hippocampal formation [nTPM]":"90.2","Brain RNA - hypothalamus [nTPM]":"126.8","Brain RNA - medulla oblongata [nTPM]":"105.8","Brain RNA - midbrain [nTPM]":"107.0","Brain RNA - pons [nTPM]":"120.2","Brain RNA - spinal cord [nTPM]":"111.4","Brain RNA - thalamus [nTPM]":"101.7","Brain RNA - white matter [nTPM]":"163.9","Single Cell Type RNA - Adipocytes [nTPM]":"227.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"185.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"273.5","Single Cell Type RNA - Astrocytes [nTPM]":"38.5","Single Cell Type RNA - B-cells [nTPM]":"254.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"292.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1225.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"573.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"192.9","Single Cell Type RNA - Bipolar cells [nTPM]":"97.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"193.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"166.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"803.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"97.2","Single Cell Type RNA - Club cells [nTPM]":"416.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"112.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"352.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"505.9","Single Cell Type RNA - dendritic cells [nTPM]":"408.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"426.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"45.0","Single Cell Type RNA - Ductal cells [nTPM]":"415.0","Single Cell Type RNA - Early spermatids [nTPM]":"86.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"372.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"402.2","Single Cell Type RNA - Endothelial cells [nTPM]":"247.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"508.8","Single Cell Type RNA - Erythroid cells [nTPM]":"82.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"258.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"955.2","Single Cell Type RNA - Fibroblasts [nTPM]":"455.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"258.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"467.4","Single Cell Type RNA - granulocytes [nTPM]":"334.2","Single Cell Type RNA - Granulosa cells [nTPM]":"304.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"147.4","Single Cell Type RNA - Hepatocytes [nTPM]":"379.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"449.4","Single Cell Type RNA - Horizontal cells [nTPM]":"63.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"34.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"508.2","Single Cell Type RNA - Ionocytes [nTPM]":"195.3","Single Cell Type RNA - Kupffer cells [nTPM]":"133.4","Single Cell Type RNA - Langerhans cells [nTPM]":"271.0","Single Cell Type RNA - Late spermatids [nTPM]":"50.3","Single Cell Type RNA - Leydig cells [nTPM]":"175.2","Single Cell Type RNA - Macrophages [nTPM]":"261.6","Single Cell Type RNA - Melanocytes [nTPM]":"181.5","Single Cell Type RNA - Microglial cells [nTPM]":"30.0","Single Cell Type RNA - monocytes [nTPM]":"135.0","Single Cell Type RNA - Muller glia cells [nTPM]":"134.6","Single Cell Type RNA - NK-cells [nTPM]":"80.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"29.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"41.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"313.7","Single Cell Type RNA - Paneth cells [nTPM]":"408.3","Single Cell Type RNA - Peritubular cells [nTPM]":"174.5","Single Cell Type RNA - Plasma cells [nTPM]":"1041.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"360.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"196.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"121.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"267.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"176.6","Single Cell Type RNA - Sertoli cells [nTPM]":"118.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"245.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"673.8","Single Cell Type RNA - Spermatocytes [nTPM]":"435.7","Single Cell Type RNA - Spermatogonia [nTPM]":"204.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"167.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"236.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1327.5","Single Cell Type RNA - T-cells [nTPM]":"323.8","Single Cell Type RNA - Theca cells [nTPM]":"243.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"376.4","Single Cell Type RNA - Urothelial cells [nTPM]":"795.4"},{"Gene":"HSPD1","Gene synonym":["GroEL","HSP60","SPG13"],"Ensembl":"ENSG00000144381","Gene description":"Heat shock protein family D (Hsp60) member 1","Uniprot":["P10809"],"Chromosome":"2","Position":"197486584-197516737","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Chaperone","Isomerase"],"Disease involvement":["Cancer-related genes","Disease variant","Hereditary spastic paraplegia","Leukodystrophy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"790.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"1737.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001523","CAB002775","HPA050025","CAB072816"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"18000000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB002775":null,"CAB072816":null,"HPA001523":"AB_1079028","HPA050025":"AB_2680995"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.61e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.25e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.63e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Tissue RNA - adipose tissue [nTPM]":"179.4","Tissue RNA - adrenal gland [nTPM]":"790.6","Tissue RNA - amygdala [nTPM]":"188.6","Tissue RNA - appendix [nTPM]":"128.3","Tissue RNA - basal ganglia [nTPM]":"191.6","Tissue RNA - bone marrow [nTPM]":"110.6","Tissue RNA - breast [nTPM]":"168.8","Tissue RNA - cerebellum [nTPM]":"204.9","Tissue RNA - cerebral cortex [nTPM]":"401.9","Tissue RNA - cervix [nTPM]":"96.9","Tissue RNA - choroid plexus [nTPM]":"217.8","Tissue RNA - colon [nTPM]":"170.0","Tissue RNA - duodenum [nTPM]":"158.1","Tissue RNA - endometrium 1 [nTPM]":"90.8","Tissue RNA - epididymis [nTPM]":"89.3","Tissue RNA - esophagus [nTPM]":"124.5","Tissue RNA - fallopian tube [nTPM]":"132.6","Tissue RNA - gallbladder [nTPM]":"69.1","Tissue RNA - heart muscle [nTPM]":"145.0","Tissue RNA - hippocampal formation [nTPM]":"184.3","Tissue RNA - hypothalamus [nTPM]":"198.6","Tissue RNA - kidney [nTPM]":"374.9","Tissue RNA - liver [nTPM]":"462.6","Tissue RNA - lung [nTPM]":"136.6","Tissue RNA - lymph node [nTPM]":"149.2","Tissue RNA - medulla oblongata [nTPM]":"199.6","Tissue RNA - midbrain [nTPM]":"198.5","Tissue RNA - ovary [nTPM]":"167.6","Tissue RNA - pancreas [nTPM]":"219.0","Tissue RNA - parathyroid gland [nTPM]":"159.2","Tissue RNA - pituitary gland [nTPM]":"116.0","Tissue RNA - placenta [nTPM]":"148.6","Tissue RNA - pons [nTPM]":"205.3","Tissue RNA - prostate [nTPM]":"104.5","Tissue RNA - rectum [nTPM]":"195.1","Tissue RNA - retina [nTPM]":"71.8","Tissue RNA - salivary gland [nTPM]":"93.9","Tissue RNA - seminal vesicle [nTPM]":"93.6","Tissue RNA - skeletal muscle [nTPM]":"162.7","Tissue RNA - skin 1 [nTPM]":"83.3","Tissue RNA - small intestine [nTPM]":"148.7","Tissue RNA - smooth muscle [nTPM]":"104.5","Tissue RNA - spinal cord [nTPM]":"195.1","Tissue RNA - spleen [nTPM]":"94.6","Tissue RNA - stomach 1 [nTPM]":"155.4","Tissue RNA - testis [nTPM]":"57.6","Tissue RNA - thalamus [nTPM]":"198.6","Tissue RNA - thymus [nTPM]":"99.3","Tissue RNA - thyroid gland [nTPM]":"138.7","Tissue RNA - tongue [nTPM]":"176.7","Tissue RNA - tonsil [nTPM]":"172.7","Tissue RNA - urinary bladder [nTPM]":"144.6","Tissue RNA - vagina [nTPM]":"92.3","Tissue RNA - white matter [nTPM]":"201.4","Cell RNA - A-431 [nTPM]":"559.7","Cell RNA - A549 [nTPM]":"650.1","Cell RNA - AF22 [nTPM]":"541.3","Cell RNA - AN3-CA [nTPM]":"496.9","Cell RNA - ASC diff [nTPM]":"373.6","Cell RNA - ASC TERT1 [nTPM]":"389.2","Cell RNA - BEWO [nTPM]":"786.5","Cell RNA - BJ [nTPM]":"573.2","Cell RNA - BJ hTERT+ [nTPM]":"304.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"686.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"495.6","Cell RNA - CACO-2 [nTPM]":"2219.1","Cell RNA - CAPAN-2 [nTPM]":"326.2","Cell RNA - Daudi [nTPM]":"1724.4","Cell RNA - EFO-21 [nTPM]":"730.0","Cell RNA - fHDF\/TERT166 [nTPM]":"304.1","Cell RNA - GAMG [nTPM]":"834.2","Cell RNA - HaCaT [nTPM]":"538.4","Cell RNA - HAP1 [nTPM]":"2232.9","Cell RNA - HBEC3-KT [nTPM]":"633.2","Cell RNA - HBF TERT88 [nTPM]":"943.0","Cell RNA - HDLM-2 [nTPM]":"417.0","Cell RNA - HEK 293 [nTPM]":"888.2","Cell RNA - HEL [nTPM]":"1209.8","Cell RNA - HeLa [nTPM]":"984.8","Cell RNA - Hep G2 [nTPM]":"2562.8","Cell RNA - HHSteC [nTPM]":"353.2","Cell RNA - HL-60 [nTPM]":"1331.4","Cell RNA - HMC-1 [nTPM]":"349.1","Cell RNA - HSkMC [nTPM]":"445.5","Cell RNA - hTCEpi [nTPM]":"717.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"599.5","Cell RNA - hTERT-HME1 [nTPM]":"1053.2","Cell RNA - hTERT-RPE1 [nTPM]":"471.4","Cell RNA - HUVEC TERT2 [nTPM]":"542.6","Cell RNA - JURKAT [nTPM]":"919.1","Cell RNA - K-562 [nTPM]":"1535.3","Cell RNA - Karpas-707 [nTPM]":"606.8","Cell RNA - LHCN-M2 [nTPM]":"501.7","Cell RNA - MCF7 [nTPM]":"690.4","Cell RNA - MOLT-4 [nTPM]":"853.6","Cell RNA - NB-4 [nTPM]":"1304.2","Cell RNA - NTERA-2 [nTPM]":"1086.4","Cell RNA - OE19 [nTPM]":"735.2","Cell RNA - PC-3 [nTPM]":"1424.9","Cell RNA - REH [nTPM]":"1000.1","Cell RNA - RH-30 [nTPM]":"679.7","Cell RNA - RPMI-8226 [nTPM]":"1235.5","Cell RNA - RPTEC TERT1 [nTPM]":"709.5","Cell RNA - RT4 [nTPM]":"539.7","Cell RNA - SCLC-21H [nTPM]":"716.5","Cell RNA - SH-SY5Y [nTPM]":"400.8","Cell RNA - SiHa [nTPM]":"582.0","Cell RNA - SK-BR-3 [nTPM]":"608.5","Cell RNA - SK-MEL-30 [nTPM]":"771.0","Cell RNA - SuSa [nTPM]":"1116.3","Cell RNA - T-47d [nTPM]":"425.0","Cell RNA - THP-1 [nTPM]":"789.4","Cell RNA - TIME [nTPM]":"242.2","Cell RNA - U-138 MG [nTPM]":"405.8","Cell RNA - U-2 OS [nTPM]":"570.4","Cell RNA - U-2197 [nTPM]":"532.8","Cell RNA - U-251 MG [nTPM]":"910.0","Cell RNA - U-266\/70 [nTPM]":"331.1","Cell RNA - U-266\/84 [nTPM]":"861.4","Cell RNA - U-698 [nTPM]":"1399.5","Cell RNA - U-87 MG [nTPM]":"485.7","Cell RNA - U-937 [nTPM]":"795.3","Cell RNA - WM-115 [nTPM]":"456.7","Blood RNA - basophil [nTPM]":"12.1","Blood RNA - classical monocyte [nTPM]":"52.3","Blood RNA - eosinophil [nTPM]":"11.4","Blood RNA - gdT-cell [nTPM]":"36.4","Blood RNA - intermediate monocyte [nTPM]":"81.8","Blood RNA - MAIT T-cell [nTPM]":"71.7","Blood RNA - memory B-cell [nTPM]":"63.8","Blood RNA - memory CD4 T-cell [nTPM]":"59.6","Blood RNA - memory CD8 T-cell [nTPM]":"54.3","Blood RNA - myeloid DC [nTPM]":"84.6","Blood RNA - naive B-cell [nTPM]":"54.0","Blood RNA - naive CD4 T-cell [nTPM]":"81.0","Blood RNA - naive CD8 T-cell [nTPM]":"70.3","Blood RNA - neutrophil [nTPM]":"11.0","Blood RNA - NK-cell [nTPM]":"62.6","Blood RNA - non-classical monocyte [nTPM]":"72.1","Blood RNA - plasmacytoid DC [nTPM]":"49.4","Blood RNA - T-reg [nTPM]":"51.8","Blood RNA - total PBMC [nTPM]":"70.6","Brain RNA - amygdala [nTPM]":"188.6","Brain RNA - basal ganglia [nTPM]":"191.6","Brain RNA - cerebellum [nTPM]":"204.9","Brain RNA - cerebral cortex [nTPM]":"401.9","Brain RNA - hippocampal formation [nTPM]":"184.3","Brain RNA - hypothalamus [nTPM]":"198.6","Brain RNA - medulla oblongata [nTPM]":"199.6","Brain RNA - midbrain [nTPM]":"198.5","Brain RNA - pons [nTPM]":"205.3","Brain RNA - spinal cord [nTPM]":"195.1","Brain RNA - thalamus [nTPM]":"198.6","Brain RNA - white matter [nTPM]":"201.4","Single Cell Type RNA - Adipocytes [nTPM]":"216.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"166.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"172.5","Single Cell Type RNA - Astrocytes [nTPM]":"38.8","Single Cell Type RNA - B-cells [nTPM]":"220.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"246.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1737.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"247.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"264.0","Single Cell Type RNA - Bipolar cells [nTPM]":"75.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"216.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"263.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"239.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"195.9","Single Cell Type RNA - Club cells [nTPM]":"287.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"79.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"256.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"825.7","Single Cell Type RNA - dendritic cells [nTPM]":"197.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"213.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"375.6","Single Cell Type RNA - Ductal cells [nTPM]":"235.0","Single Cell Type RNA - Early spermatids [nTPM]":"6.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"322.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"304.5","Single Cell Type RNA - Endothelial cells [nTPM]":"233.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"274.6","Single Cell Type RNA - Erythroid cells [nTPM]":"241.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"31.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"145.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"419.8","Single Cell Type RNA - Fibroblasts [nTPM]":"356.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"215.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"445.2","Single Cell Type RNA - granulocytes [nTPM]":"299.5","Single Cell Type RNA - Granulosa cells [nTPM]":"407.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"63.1","Single Cell Type RNA - Hepatocytes [nTPM]":"312.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"328.0","Single Cell Type RNA - Horizontal cells [nTPM]":"95.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"47.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"302.2","Single Cell Type RNA - Ionocytes [nTPM]":"166.8","Single Cell Type RNA - Kupffer cells [nTPM]":"88.6","Single Cell Type RNA - Langerhans cells [nTPM]":"479.3","Single Cell Type RNA - Late spermatids [nTPM]":"12.8","Single Cell Type RNA - Leydig cells [nTPM]":"130.5","Single Cell Type RNA - Macrophages [nTPM]":"381.9","Single Cell Type RNA - Melanocytes [nTPM]":"163.7","Single Cell Type RNA - Microglial cells [nTPM]":"30.0","Single Cell Type RNA - monocytes [nTPM]":"138.5","Single Cell Type RNA - Muller glia cells [nTPM]":"125.7","Single Cell Type RNA - NK-cells [nTPM]":"68.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"35.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"171.4","Single Cell Type RNA - Paneth cells [nTPM]":"163.2","Single Cell Type RNA - Peritubular cells [nTPM]":"113.6","Single Cell Type RNA - Plasma cells [nTPM]":"322.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"705.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"160.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"797.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"328.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"117.1","Single Cell Type RNA - Sertoli cells [nTPM]":"85.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"199.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"471.7","Single Cell Type RNA - Spermatocytes [nTPM]":"88.5","Single Cell Type RNA - Spermatogonia [nTPM]":"106.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"262.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"207.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1001.2","Single Cell Type RNA - T-cells [nTPM]":"467.2","Single Cell Type RNA - Theca cells [nTPM]":"1017.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"512.1","Single Cell Type RNA - Urothelial cells [nTPM]":"861.5"},{"Gene":"HTRA1","Gene synonym":["ARMD7","HtrA","IGFBP5-protease","PRSS11"],"Ensembl":"ENSG00000166033","Gene description":"HtrA serine peptidase 1","Uniprot":["Q92743"],"Chromosome":"10","Position":"122458551-122514907","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Growth factor binding","Hydrolase","Protease","Serine protease"],"Disease involvement":["Age-related macular degeneration","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Fibroblasts":"269.3","Granulosa cells":"731.6","Horizontal cells":"625.9","Muller glia cells":"373.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"2417.8","ASC TERT1":"889.4","fHDF\/TERT166":"862.3","HSkMC":"1581.4","LHCN-M2":"1238.2","U-87 MG":"1004.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036655"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":24800000,"Blood concentration - Conc. blood MS [pg\/L]":"7600000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA036655":"AB_10671966"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.90e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.62e-6"},"Tissue RNA - adipose tissue [nTPM]":"246.0","Tissue RNA - adrenal gland [nTPM]":"81.3","Tissue RNA - amygdala [nTPM]":"382.1","Tissue RNA - appendix [nTPM]":"37.0","Tissue RNA - basal ganglia [nTPM]":"436.6","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"202.8","Tissue RNA - cerebellum [nTPM]":"422.6","Tissue RNA - cerebral cortex [nTPM]":"595.7","Tissue RNA - cervix [nTPM]":"352.1","Tissue RNA - choroid plexus [nTPM]":"316.2","Tissue RNA - colon [nTPM]":"154.8","Tissue RNA - duodenum [nTPM]":"20.8","Tissue RNA - endometrium 1 [nTPM]":"197.1","Tissue RNA - epididymis [nTPM]":"247.1","Tissue RNA - esophagus [nTPM]":"57.8","Tissue RNA - fallopian tube [nTPM]":"122.9","Tissue RNA - gallbladder [nTPM]":"301.2","Tissue RNA - heart muscle [nTPM]":"114.7","Tissue RNA - hippocampal formation [nTPM]":"377.7","Tissue RNA - hypothalamus [nTPM]":"411.4","Tissue RNA - kidney [nTPM]":"230.9","Tissue RNA - liver [nTPM]":"226.4","Tissue RNA - lung [nTPM]":"69.9","Tissue RNA - lymph node [nTPM]":"39.9","Tissue RNA - medulla oblongata [nTPM]":"427.1","Tissue RNA - midbrain [nTPM]":"447.0","Tissue RNA - ovary [nTPM]":"425.5","Tissue RNA - pancreas [nTPM]":"55.9","Tissue RNA - parathyroid gland [nTPM]":"111.8","Tissue RNA - pituitary gland [nTPM]":"184.1","Tissue RNA - placenta [nTPM]":"281.9","Tissue RNA - pons [nTPM]":"425.3","Tissue RNA - prostate [nTPM]":"85.7","Tissue RNA - rectum [nTPM]":"51.8","Tissue RNA - retina [nTPM]":"243.6","Tissue RNA - salivary gland [nTPM]":"101.1","Tissue RNA - seminal vesicle [nTPM]":"114.5","Tissue RNA - skeletal muscle [nTPM]":"31.1","Tissue RNA - skin 1 [nTPM]":"130.5","Tissue RNA - small intestine [nTPM]":"73.5","Tissue RNA - smooth muscle [nTPM]":"152.3","Tissue RNA - spinal cord [nTPM]":"382.1","Tissue RNA - spleen [nTPM]":"54.2","Tissue RNA - stomach 1 [nTPM]":"87.3","Tissue RNA - testis [nTPM]":"19.5","Tissue RNA - thalamus [nTPM]":"423.6","Tissue RNA - thymus [nTPM]":"21.2","Tissue RNA - thyroid gland [nTPM]":"78.8","Tissue RNA - tongue [nTPM]":"80.9","Tissue RNA - tonsil [nTPM]":"27.3","Tissue RNA - urinary bladder [nTPM]":"137.3","Tissue RNA - vagina [nTPM]":"188.3","Tissue RNA - white matter [nTPM]":"464.2","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"45.6","Cell RNA - AF22 [nTPM]":"19.4","Cell RNA - AN3-CA [nTPM]":"5.7","Cell RNA - ASC diff [nTPM]":"2417.8","Cell RNA - ASC TERT1 [nTPM]":"889.4","Cell RNA - BEWO [nTPM]":"0.8","Cell RNA - BJ [nTPM]":"108.3","Cell RNA - BJ hTERT+ [nTPM]":"196.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"44.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.6","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"29.0","Cell RNA - fHDF\/TERT166 [nTPM]":"862.3","Cell RNA - GAMG [nTPM]":"68.6","Cell RNA - HaCaT [nTPM]":"12.8","Cell RNA - HAP1 [nTPM]":"7.6","Cell RNA - HBEC3-KT [nTPM]":"124.4","Cell RNA - HBF TERT88 [nTPM]":"6.2","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"4.9","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"65.4","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"123.7","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.9","Cell RNA - HSkMC [nTPM]":"1581.4","Cell RNA - hTCEpi [nTPM]":"444.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.8","Cell RNA - hTERT-HME1 [nTPM]":"205.3","Cell RNA - hTERT-RPE1 [nTPM]":"503.6","Cell RNA - HUVEC TERT2 [nTPM]":"207.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"1.5","Cell RNA - LHCN-M2 [nTPM]":"1238.2","Cell RNA - MCF7 [nTPM]":"22.3","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.7","Cell RNA - NTERA-2 [nTPM]":"20.9","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"67.6","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"1.3","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"282.6","Cell RNA - RT4 [nTPM]":"2.2","Cell RNA - SCLC-21H [nTPM]":"1.2","Cell RNA - SH-SY5Y [nTPM]":"3.9","Cell RNA - SiHa [nTPM]":"272.1","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"122.2","Cell RNA - SuSa [nTPM]":"91.4","Cell RNA - T-47d [nTPM]":"8.6","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"136.0","Cell RNA - U-138 MG [nTPM]":"309.9","Cell RNA - U-2 OS [nTPM]":"4.5","Cell RNA - U-2197 [nTPM]":"141.3","Cell RNA - U-251 MG [nTPM]":"94.1","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"1004.6","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"148.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"382.1","Brain RNA - basal ganglia [nTPM]":"436.6","Brain RNA - cerebellum [nTPM]":"422.6","Brain RNA - cerebral cortex [nTPM]":"595.7","Brain RNA - hippocampal formation [nTPM]":"377.7","Brain RNA - hypothalamus [nTPM]":"411.4","Brain RNA - medulla oblongata [nTPM]":"427.1","Brain RNA - midbrain [nTPM]":"447.0","Brain RNA - pons [nTPM]":"425.3","Brain RNA - spinal cord [nTPM]":"382.1","Brain RNA - thalamus [nTPM]":"423.6","Brain RNA - white matter [nTPM]":"464.2","Single Cell Type RNA - Adipocytes [nTPM]":"55.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.9","Single Cell Type RNA - Astrocytes [nTPM]":"116.5","Single Cell Type RNA - B-cells [nTPM]":"0.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"44.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.9","Single Cell Type RNA - Bipolar cells [nTPM]":"53.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"31.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"26.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"0.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"64.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"54.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"30.9","Single Cell Type RNA - dendritic cells [nTPM]":"1.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"76.5","Single Cell Type RNA - Endothelial cells [nTPM]":"107.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"164.6","Single Cell Type RNA - Fibroblasts [nTPM]":"269.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.4","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"731.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"57.8","Single Cell Type RNA - Hepatocytes [nTPM]":"157.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"51.3","Single Cell Type RNA - Horizontal cells [nTPM]":"625.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"31.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"18.1","Single Cell Type RNA - Langerhans cells [nTPM]":"59.9","Single Cell Type RNA - Late spermatids [nTPM]":"4.2","Single Cell Type RNA - Leydig cells [nTPM]":"31.7","Single Cell Type RNA - Macrophages [nTPM]":"22.0","Single Cell Type RNA - Melanocytes [nTPM]":"46.2","Single Cell Type RNA - Microglial cells [nTPM]":"86.2","Single Cell Type RNA - monocytes [nTPM]":"8.5","Single Cell Type RNA - Muller glia cells [nTPM]":"373.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"193.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"112.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.7","Single Cell Type RNA - Paneth cells [nTPM]":"1.3","Single Cell Type RNA - Peritubular cells [nTPM]":"77.5","Single Cell Type RNA - Plasma cells [nTPM]":"1.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"150.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"63.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"140.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"30.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"87.7","Single Cell Type RNA - T-cells [nTPM]":"7.2","Single Cell Type RNA - Theca cells [nTPM]":"2.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"11.9"},{"Gene":"HTRA2","Gene synonym":["OMI","PARK13","PRSS25"],"Ensembl":"ENSG00000115317","Gene description":"HtrA serine peptidase 2","Uniprot":["O43464"],"Chromosome":"2","Position":"74529725-74533332","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"118.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004004","HPA006602","HPA027366"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"260000","Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB004004":"AB_326421","HPA006602":"AB_2667622","HPA027366":"AB_1851301"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.77e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.4","Tissue RNA - adrenal gland [nTPM]":"8.6","Tissue RNA - amygdala [nTPM]":"8.1","Tissue RNA - appendix [nTPM]":"8.1","Tissue RNA - basal ganglia [nTPM]":"8.7","Tissue RNA - bone marrow [nTPM]":"11.1","Tissue RNA - breast [nTPM]":"6.8","Tissue RNA - cerebellum [nTPM]":"9.1","Tissue RNA - cerebral cortex [nTPM]":"9.7","Tissue RNA - cervix [nTPM]":"7.1","Tissue RNA - choroid plexus [nTPM]":"7.7","Tissue RNA - colon [nTPM]":"6.4","Tissue RNA - duodenum [nTPM]":"6.9","Tissue RNA - endometrium 1 [nTPM]":"6.9","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"6.0","Tissue RNA - fallopian tube [nTPM]":"7.1","Tissue RNA - gallbladder [nTPM]":"4.7","Tissue RNA - heart muscle [nTPM]":"9.4","Tissue RNA - hippocampal formation [nTPM]":"8.1","Tissue RNA - hypothalamus [nTPM]":"8.3","Tissue RNA - kidney [nTPM]":"8.1","Tissue RNA - liver [nTPM]":"6.5","Tissue RNA - lung [nTPM]":"6.6","Tissue RNA - lymph node [nTPM]":"7.8","Tissue RNA - medulla oblongata [nTPM]":"8.6","Tissue RNA - midbrain [nTPM]":"8.5","Tissue RNA - ovary [nTPM]":"10.9","Tissue RNA - pancreas [nTPM]":"7.4","Tissue RNA - parathyroid gland [nTPM]":"9.4","Tissue RNA - pituitary gland [nTPM]":"4.7","Tissue RNA - placenta [nTPM]":"6.3","Tissue RNA - pons [nTPM]":"8.3","Tissue RNA - prostate [nTPM]":"4.8","Tissue RNA - rectum [nTPM]":"3.3","Tissue RNA - retina [nTPM]":"2.5","Tissue RNA - salivary gland [nTPM]":"8.5","Tissue RNA - seminal vesicle [nTPM]":"5.3","Tissue RNA - skeletal muscle [nTPM]":"14.5","Tissue RNA - skin 1 [nTPM]":"5.4","Tissue RNA - small intestine [nTPM]":"7.9","Tissue RNA - smooth muscle [nTPM]":"5.3","Tissue RNA - spinal cord [nTPM]":"8.2","Tissue RNA - spleen [nTPM]":"9.9","Tissue RNA - stomach 1 [nTPM]":"6.4","Tissue RNA - testis [nTPM]":"6.2","Tissue RNA - thalamus [nTPM]":"9.6","Tissue RNA - thymus [nTPM]":"9.1","Tissue RNA - thyroid gland [nTPM]":"6.8","Tissue RNA - tongue [nTPM]":"9.0","Tissue RNA - tonsil [nTPM]":"4.8","Tissue RNA - urinary bladder [nTPM]":"6.5","Tissue RNA - vagina [nTPM]":"5.8","Tissue RNA - white matter [nTPM]":"9.2","Cell RNA - A-431 [nTPM]":"19.1","Cell RNA - A549 [nTPM]":"14.7","Cell RNA - AF22 [nTPM]":"14.7","Cell RNA - AN3-CA [nTPM]":"12.6","Cell RNA - ASC diff [nTPM]":"21.3","Cell RNA - ASC TERT1 [nTPM]":"9.0","Cell RNA - BEWO [nTPM]":"30.1","Cell RNA - BJ [nTPM]":"17.0","Cell RNA - BJ hTERT+ [nTPM]":"10.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.0","Cell RNA - CACO-2 [nTPM]":"21.1","Cell RNA - CAPAN-2 [nTPM]":"8.5","Cell RNA - Daudi [nTPM]":"16.6","Cell RNA - EFO-21 [nTPM]":"12.9","Cell RNA - fHDF\/TERT166 [nTPM]":"10.7","Cell RNA - GAMG [nTPM]":"26.0","Cell RNA - HaCaT [nTPM]":"19.7","Cell RNA - HAP1 [nTPM]":"12.0","Cell RNA - HBEC3-KT [nTPM]":"19.6","Cell RNA - HBF TERT88 [nTPM]":"2.4","Cell RNA - HDLM-2 [nTPM]":"34.0","Cell RNA - HEK 293 [nTPM]":"31.4","Cell RNA - HEL [nTPM]":"33.3","Cell RNA - HeLa [nTPM]":"10.8","Cell RNA - Hep G2 [nTPM]":"19.0","Cell RNA - HHSteC [nTPM]":"19.8","Cell RNA - HL-60 [nTPM]":"15.3","Cell RNA - HMC-1 [nTPM]":"22.4","Cell RNA - HSkMC [nTPM]":"9.9","Cell RNA - hTCEpi [nTPM]":"13.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.4","Cell RNA - hTERT-HME1 [nTPM]":"19.5","Cell RNA - hTERT-RPE1 [nTPM]":"18.4","Cell RNA - HUVEC TERT2 [nTPM]":"14.2","Cell RNA - JURKAT [nTPM]":"23.5","Cell RNA - K-562 [nTPM]":"43.9","Cell RNA - Karpas-707 [nTPM]":"24.9","Cell RNA - LHCN-M2 [nTPM]":"9.7","Cell RNA - MCF7 [nTPM]":"14.1","Cell RNA - MOLT-4 [nTPM]":"22.0","Cell RNA - NB-4 [nTPM]":"31.1","Cell RNA - NTERA-2 [nTPM]":"10.0","Cell RNA - OE19 [nTPM]":"22.8","Cell RNA - PC-3 [nTPM]":"37.7","Cell RNA - REH [nTPM]":"15.8","Cell RNA - RH-30 [nTPM]":"37.0","Cell RNA - RPMI-8226 [nTPM]":"17.1","Cell RNA - RPTEC TERT1 [nTPM]":"9.6","Cell RNA - RT4 [nTPM]":"8.2","Cell RNA - SCLC-21H [nTPM]":"15.1","Cell RNA - SH-SY5Y [nTPM]":"17.7","Cell RNA - SiHa [nTPM]":"8.9","Cell RNA - SK-BR-3 [nTPM]":"18.6","Cell RNA - SK-MEL-30 [nTPM]":"32.5","Cell RNA - SuSa [nTPM]":"7.3","Cell RNA - T-47d [nTPM]":"9.3","Cell RNA - THP-1 [nTPM]":"13.2","Cell RNA - TIME [nTPM]":"10.6","Cell RNA - U-138 MG [nTPM]":"19.2","Cell RNA - U-2 OS [nTPM]":"19.7","Cell RNA - U-2197 [nTPM]":"33.4","Cell RNA - U-251 MG [nTPM]":"35.3","Cell RNA - U-266\/70 [nTPM]":"29.5","Cell RNA - U-266\/84 [nTPM]":"10.2","Cell RNA - U-698 [nTPM]":"9.8","Cell RNA - U-87 MG [nTPM]":"13.6","Cell RNA - U-937 [nTPM]":"23.4","Cell RNA - WM-115 [nTPM]":"13.0","Blood RNA - basophil [nTPM]":"5.8","Blood RNA - classical monocyte [nTPM]":"7.0","Blood RNA - eosinophil [nTPM]":"4.0","Blood RNA - gdT-cell [nTPM]":"4.8","Blood RNA - intermediate monocyte [nTPM]":"5.7","Blood RNA - MAIT T-cell [nTPM]":"5.8","Blood RNA - memory B-cell [nTPM]":"11.0","Blood RNA - memory CD4 T-cell [nTPM]":"4.8","Blood RNA - memory CD8 T-cell [nTPM]":"4.1","Blood RNA - myeloid DC [nTPM]":"8.6","Blood RNA - naive B-cell [nTPM]":"9.9","Blood RNA - naive CD4 T-cell [nTPM]":"4.3","Blood RNA - naive CD8 T-cell [nTPM]":"4.1","Blood RNA - neutrophil [nTPM]":"2.6","Blood RNA - NK-cell [nTPM]":"5.0","Blood RNA - non-classical monocyte [nTPM]":"4.5","Blood RNA - plasmacytoid DC [nTPM]":"4.5","Blood RNA - T-reg [nTPM]":"5.7","Blood RNA - total PBMC [nTPM]":"5.5","Brain RNA - amygdala [nTPM]":"8.1","Brain RNA - basal ganglia [nTPM]":"8.7","Brain RNA - cerebellum [nTPM]":"9.1","Brain RNA - cerebral cortex [nTPM]":"9.7","Brain RNA - hippocampal formation [nTPM]":"8.1","Brain RNA - hypothalamus [nTPM]":"8.3","Brain RNA - medulla oblongata [nTPM]":"8.6","Brain RNA - midbrain [nTPM]":"8.5","Brain RNA - pons [nTPM]":"8.3","Brain RNA - spinal cord [nTPM]":"8.2","Brain RNA - thalamus [nTPM]":"9.6","Brain RNA - white matter [nTPM]":"9.2","Single Cell Type RNA - Adipocytes [nTPM]":"30.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"6.2","Single Cell Type RNA - B-cells [nTPM]":"27.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"19.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"33.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"12.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"15.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"24.7","Single Cell Type RNA - dendritic cells [nTPM]":"25.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"32.4","Single Cell Type RNA - Early spermatids [nTPM]":"30.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.1","Single Cell Type RNA - Endothelial cells [nTPM]":"29.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.0","Single Cell Type RNA - Erythroid cells [nTPM]":"118.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"37.8","Single Cell Type RNA - Fibroblasts [nTPM]":"23.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.9","Single Cell Type RNA - granulocytes [nTPM]":"27.3","Single Cell Type RNA - Granulosa cells [nTPM]":"20.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.9","Single Cell Type RNA - Hepatocytes [nTPM]":"12.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"31.5","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.3","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"10.7","Single Cell Type RNA - Langerhans cells [nTPM]":"19.4","Single Cell Type RNA - Late spermatids [nTPM]":"48.9","Single Cell Type RNA - Leydig cells [nTPM]":"24.8","Single Cell Type RNA - Macrophages [nTPM]":"14.6","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"26.3","Single Cell Type RNA - Muller glia cells [nTPM]":"20.2","Single Cell Type RNA - NK-cells [nTPM]":"30.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"26.1","Single Cell Type RNA - Paneth cells [nTPM]":"16.8","Single Cell Type RNA - Peritubular cells [nTPM]":"20.7","Single Cell Type RNA - Plasma cells [nTPM]":"36.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"21.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"36.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.3","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"56.5","Single Cell Type RNA - Spermatocytes [nTPM]":"64.3","Single Cell Type RNA - Spermatogonia [nTPM]":"43.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.2","Single Cell Type RNA - T-cells [nTPM]":"20.6","Single Cell Type RNA - Theca cells [nTPM]":"27.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.0","Single Cell Type RNA - Urothelial cells [nTPM]":"15.7"},{"Gene":"HUWE1","Gene synonym":["Ib772","KIAA0312","UREB1"],"Ensembl":"ENSG00000086758","Gene description":"HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1","Uniprot":["Q7Z6Z7"],"Chromosome":"X","Position":"53532096-53686728","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Biological rhythms","Differentiation","DNA damage","DNA repair","Ubl conjugation pathway"],"Molecular function":["DNA-binding","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Granulosa cells":"507.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002548","CAB022718"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"73000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB022718":null,"HPA002548":"AB_1080489"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Tissue RNA - adipose tissue [nTPM]":"37.7","Tissue RNA - adrenal gland [nTPM]":"46.1","Tissue RNA - amygdala [nTPM]":"55.6","Tissue RNA - appendix [nTPM]":"21.1","Tissue RNA - basal ganglia [nTPM]":"57.4","Tissue RNA - bone marrow [nTPM]":"26.7","Tissue RNA - breast [nTPM]":"37.4","Tissue RNA - cerebellum [nTPM]":"57.6","Tissue RNA - cerebral cortex [nTPM]":"69.6","Tissue RNA - cervix [nTPM]":"39.8","Tissue RNA - choroid plexus [nTPM]":"42.0","Tissue RNA - colon [nTPM]":"49.4","Tissue RNA - duodenum [nTPM]":"17.6","Tissue RNA - endometrium 1 [nTPM]":"45.6","Tissue RNA - epididymis [nTPM]":"52.6","Tissue RNA - esophagus [nTPM]":"48.4","Tissue RNA - fallopian tube [nTPM]":"40.7","Tissue RNA - gallbladder [nTPM]":"18.5","Tissue RNA - heart muscle [nTPM]":"57.1","Tissue RNA - hippocampal formation [nTPM]":"62.6","Tissue RNA - hypothalamus [nTPM]":"61.3","Tissue RNA - kidney [nTPM]":"45.2","Tissue RNA - liver [nTPM]":"41.8","Tissue RNA - lung [nTPM]":"36.1","Tissue RNA - lymph node [nTPM]":"26.6","Tissue RNA - medulla oblongata [nTPM]":"58.7","Tissue RNA - midbrain [nTPM]":"67.8","Tissue RNA - ovary [nTPM]":"54.0","Tissue RNA - pancreas [nTPM]":"45.9","Tissue RNA - parathyroid gland [nTPM]":"43.2","Tissue RNA - pituitary gland [nTPM]":"54.2","Tissue RNA - placenta [nTPM]":"24.0","Tissue RNA - pons [nTPM]":"73.2","Tissue RNA - prostate [nTPM]":"38.4","Tissue RNA - rectum [nTPM]":"22.7","Tissue RNA - retina [nTPM]":"40.0","Tissue RNA - salivary gland [nTPM]":"38.9","Tissue RNA - seminal vesicle [nTPM]":"28.6","Tissue RNA - skeletal muscle [nTPM]":"101.0","Tissue RNA - skin 1 [nTPM]":"59.3","Tissue RNA - small intestine [nTPM]":"40.2","Tissue RNA - smooth muscle [nTPM]":"28.8","Tissue RNA - spinal cord [nTPM]":"49.1","Tissue RNA - spleen [nTPM]":"42.5","Tissue RNA - stomach 1 [nTPM]":"45.5","Tissue RNA - testis [nTPM]":"43.0","Tissue RNA - thalamus [nTPM]":"65.1","Tissue RNA - thymus [nTPM]":"41.2","Tissue RNA - thyroid gland [nTPM]":"42.9","Tissue RNA - tongue [nTPM]":"58.1","Tissue RNA - tonsil [nTPM]":"30.3","Tissue RNA - urinary bladder [nTPM]":"44.6","Tissue RNA - vagina [nTPM]":"40.2","Tissue RNA - white matter [nTPM]":"57.2","Cell RNA - A-431 [nTPM]":"166.8","Cell RNA - A549 [nTPM]":"100.4","Cell RNA - AF22 [nTPM]":"64.0","Cell RNA - AN3-CA [nTPM]":"45.4","Cell RNA - ASC diff [nTPM]":"109.2","Cell RNA - ASC TERT1 [nTPM]":"64.8","Cell RNA - BEWO [nTPM]":"78.5","Cell RNA - BJ [nTPM]":"48.8","Cell RNA - BJ hTERT+ [nTPM]":"62.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"50.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"52.3","Cell RNA - CACO-2 [nTPM]":"77.0","Cell RNA - CAPAN-2 [nTPM]":"52.2","Cell RNA - Daudi [nTPM]":"86.6","Cell RNA - EFO-21 [nTPM]":"32.3","Cell RNA - fHDF\/TERT166 [nTPM]":"89.4","Cell RNA - GAMG [nTPM]":"90.4","Cell RNA - HaCaT [nTPM]":"77.8","Cell RNA - HAP1 [nTPM]":"145.6","Cell RNA - HBEC3-KT [nTPM]":"81.8","Cell RNA - HBF TERT88 [nTPM]":"68.3","Cell RNA - HDLM-2 [nTPM]":"125.6","Cell RNA - HEK 293 [nTPM]":"64.6","Cell RNA - HEL [nTPM]":"69.1","Cell RNA - HeLa [nTPM]":"91.9","Cell RNA - Hep G2 [nTPM]":"60.5","Cell RNA - HHSteC [nTPM]":"100.2","Cell RNA - HL-60 [nTPM]":"104.5","Cell RNA - HMC-1 [nTPM]":"40.6","Cell RNA - HSkMC [nTPM]":"62.4","Cell RNA - hTCEpi [nTPM]":"59.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"120.8","Cell RNA - hTERT-HME1 [nTPM]":"137.6","Cell RNA - hTERT-RPE1 [nTPM]":"49.7","Cell RNA - HUVEC TERT2 [nTPM]":"88.3","Cell RNA - JURKAT [nTPM]":"66.4","Cell RNA - K-562 [nTPM]":"70.3","Cell RNA - Karpas-707 [nTPM]":"54.5","Cell RNA - LHCN-M2 [nTPM]":"66.3","Cell RNA - MCF7 [nTPM]":"102.4","Cell RNA - MOLT-4 [nTPM]":"57.0","Cell RNA - NB-4 [nTPM]":"58.2","Cell RNA - NTERA-2 [nTPM]":"87.7","Cell RNA - OE19 [nTPM]":"45.4","Cell RNA - PC-3 [nTPM]":"71.3","Cell RNA - REH [nTPM]":"52.0","Cell RNA - RH-30 [nTPM]":"87.9","Cell RNA - RPMI-8226 [nTPM]":"52.8","Cell RNA - RPTEC TERT1 [nTPM]":"84.0","Cell RNA - RT4 [nTPM]":"113.3","Cell RNA - SCLC-21H [nTPM]":"53.1","Cell RNA - SH-SY5Y [nTPM]":"38.4","Cell RNA - SiHa [nTPM]":"137.7","Cell RNA - SK-BR-3 [nTPM]":"60.5","Cell RNA - SK-MEL-30 [nTPM]":"44.1","Cell RNA - SuSa [nTPM]":"118.7","Cell RNA - T-47d [nTPM]":"87.0","Cell RNA - THP-1 [nTPM]":"50.1","Cell RNA - TIME [nTPM]":"113.8","Cell RNA - U-138 MG [nTPM]":"46.0","Cell RNA - U-2 OS [nTPM]":"65.8","Cell RNA - U-2197 [nTPM]":"66.5","Cell RNA - U-251 MG [nTPM]":"62.9","Cell RNA - U-266\/70 [nTPM]":"47.3","Cell RNA - U-266\/84 [nTPM]":"50.2","Cell RNA - U-698 [nTPM]":"73.1","Cell RNA - U-87 MG [nTPM]":"49.2","Cell RNA - U-937 [nTPM]":"100.1","Cell RNA - WM-115 [nTPM]":"67.6","Blood RNA - basophil [nTPM]":"2.8","Blood RNA - classical monocyte [nTPM]":"2.3","Blood RNA - eosinophil [nTPM]":"4.3","Blood RNA - gdT-cell [nTPM]":"3.3","Blood RNA - intermediate monocyte [nTPM]":"1.9","Blood RNA - MAIT T-cell [nTPM]":"4.0","Blood RNA - memory B-cell [nTPM]":"2.4","Blood RNA - memory CD4 T-cell [nTPM]":"3.1","Blood RNA - memory CD8 T-cell [nTPM]":"3.5","Blood RNA - myeloid DC [nTPM]":"3.3","Blood RNA - naive B-cell [nTPM]":"2.4","Blood RNA - naive CD4 T-cell [nTPM]":"2.2","Blood RNA - naive CD8 T-cell [nTPM]":"2.2","Blood RNA - neutrophil [nTPM]":"1.9","Blood RNA - NK-cell [nTPM]":"3.5","Blood RNA - non-classical monocyte [nTPM]":"3.8","Blood RNA - plasmacytoid DC [nTPM]":"3.5","Blood RNA - T-reg [nTPM]":"2.9","Blood RNA - total PBMC [nTPM]":"1.9","Brain RNA - amygdala [nTPM]":"55.6","Brain RNA - basal ganglia [nTPM]":"57.4","Brain RNA - cerebellum [nTPM]":"57.6","Brain RNA - cerebral cortex [nTPM]":"69.6","Brain RNA - hippocampal formation [nTPM]":"62.6","Brain RNA - hypothalamus [nTPM]":"61.3","Brain RNA - medulla oblongata [nTPM]":"58.7","Brain RNA - midbrain [nTPM]":"67.8","Brain RNA - pons [nTPM]":"73.2","Brain RNA - spinal cord [nTPM]":"49.1","Brain RNA - thalamus [nTPM]":"65.1","Brain RNA - white matter [nTPM]":"57.2","Single Cell Type RNA - Adipocytes [nTPM]":"41.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"46.1","Single Cell Type RNA - Astrocytes [nTPM]":"70.2","Single Cell Type RNA - B-cells [nTPM]":"41.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"44.9","Single Cell Type RNA - Bipolar cells [nTPM]":"57.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"37.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"35.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"110.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"37.1","Single Cell Type RNA - Club cells [nTPM]":"35.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"50.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"31.0","Single Cell Type RNA - dendritic cells [nTPM]":"40.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"29.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"42.8","Single Cell Type RNA - Early spermatids [nTPM]":"28.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"45.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"59.8","Single Cell Type RNA - Endothelial cells [nTPM]":"38.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"47.6","Single Cell Type RNA - Erythroid cells [nTPM]":"47.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"94.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"35.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"34.8","Single Cell Type RNA - Fibroblasts [nTPM]":"38.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"57.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"69.6","Single Cell Type RNA - granulocytes [nTPM]":"22.1","Single Cell Type RNA - Granulosa cells [nTPM]":"507.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.9","Single Cell Type RNA - Hepatocytes [nTPM]":"48.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.8","Single Cell Type RNA - Horizontal cells [nTPM]":"82.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"85.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.1","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"31.4","Single Cell Type RNA - Langerhans cells [nTPM]":"30.8","Single Cell Type RNA - Late spermatids [nTPM]":"32.8","Single Cell Type RNA - Leydig cells [nTPM]":"28.3","Single Cell Type RNA - Macrophages [nTPM]":"34.1","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"59.0","Single Cell Type RNA - monocytes [nTPM]":"43.7","Single Cell Type RNA - Muller glia cells [nTPM]":"22.6","Single Cell Type RNA - NK-cells [nTPM]":"35.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"83.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"95.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"49.3","Single Cell Type RNA - Paneth cells [nTPM]":"20.5","Single Cell Type RNA - Peritubular cells [nTPM]":"39.1","Single Cell Type RNA - Plasma cells [nTPM]":"50.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"44.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"27.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"35.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"69.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"56.4","Single Cell Type RNA - Spermatocytes [nTPM]":"34.5","Single Cell Type RNA - Spermatogonia [nTPM]":"44.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"53.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"41.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"37.9","Single Cell Type RNA - T-cells [nTPM]":"46.7","Single Cell Type RNA - Theca cells [nTPM]":"114.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"31.7","Single Cell Type RNA - Urothelial cells [nTPM]":"42.0"},{"Gene":"HYAL1","Gene synonym":["HYAL-1","LUCA1"],"Ensembl":"ENSG00000114378","Gene description":"Hyaluronidase 1","Uniprot":["Q12794"],"Chromosome":"3","Position":"50299890-50312381","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant","Mucopolysaccharidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"201.6","lymphoid tissue":"95.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"30.0","Hepatic stellate cells":"33.2","Hepatocytes":"137.1","Proximal tubular cells":"58.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"37.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"3.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Hep G2":"100.9","SK-BR-3":"28.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002112"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"590000","Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA002112":"AB_1857412"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.07e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.56e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.4","Tissue RNA - adrenal gland [nTPM]":"21.5","Tissue RNA - amygdala [nTPM]":"5.0","Tissue RNA - appendix [nTPM]":"2.8","Tissue RNA - basal ganglia [nTPM]":"4.5","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"9.2","Tissue RNA - cerebellum [nTPM]":"6.4","Tissue RNA - cerebral cortex [nTPM]":"6.3","Tissue RNA - cervix [nTPM]":"10.8","Tissue RNA - choroid plexus [nTPM]":"18.3","Tissue RNA - colon [nTPM]":"6.8","Tissue RNA - duodenum [nTPM]":"3.4","Tissue RNA - endometrium 1 [nTPM]":"8.2","Tissue RNA - epididymis [nTPM]":"0.8","Tissue RNA - esophagus [nTPM]":"5.5","Tissue RNA - fallopian tube [nTPM]":"7.3","Tissue RNA - gallbladder [nTPM]":"13.2","Tissue RNA - heart muscle [nTPM]":"68.2","Tissue RNA - hippocampal formation [nTPM]":"4.5","Tissue RNA - hypothalamus [nTPM]":"4.0","Tissue RNA - kidney [nTPM]":"49.4","Tissue RNA - liver [nTPM]":"201.6","Tissue RNA - lung [nTPM]":"30.7","Tissue RNA - lymph node [nTPM]":"1.8","Tissue RNA - medulla oblongata [nTPM]":"5.4","Tissue RNA - midbrain [nTPM]":"4.8","Tissue RNA - ovary [nTPM]":"3.0","Tissue RNA - pancreas [nTPM]":"9.4","Tissue RNA - parathyroid gland [nTPM]":"19.9","Tissue RNA - pituitary gland [nTPM]":"3.3","Tissue RNA - placenta [nTPM]":"2.4","Tissue RNA - pons [nTPM]":"5.6","Tissue RNA - prostate [nTPM]":"4.6","Tissue RNA - rectum [nTPM]":"2.9","Tissue RNA - retina [nTPM]":"3.1","Tissue RNA - salivary gland [nTPM]":"7.3","Tissue RNA - seminal vesicle [nTPM]":"2.9","Tissue RNA - skeletal muscle [nTPM]":"15.0","Tissue RNA - skin 1 [nTPM]":"21.1","Tissue RNA - small intestine [nTPM]":"6.0","Tissue RNA - smooth muscle [nTPM]":"5.9","Tissue RNA - spinal cord [nTPM]":"3.5","Tissue RNA - spleen [nTPM]":"95.1","Tissue RNA - stomach 1 [nTPM]":"19.4","Tissue RNA - testis [nTPM]":"1.7","Tissue RNA - thalamus [nTPM]":"5.8","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"8.3","Tissue RNA - tongue [nTPM]":"19.0","Tissue RNA - tonsil [nTPM]":"1.2","Tissue RNA - urinary bladder [nTPM]":"4.8","Tissue RNA - vagina [nTPM]":"12.3","Tissue RNA - white matter [nTPM]":"4.7","Cell RNA - A-431 [nTPM]":"2.9","Cell RNA - A549 [nTPM]":"1.8","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"0.9","Cell RNA - ASC diff [nTPM]":"0.6","Cell RNA - ASC TERT1 [nTPM]":"0.7","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"11.4","Cell RNA - CAPAN-2 [nTPM]":"3.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.6","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"6.6","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"8.6","Cell RNA - Hep G2 [nTPM]":"100.9","Cell RNA - HHSteC [nTPM]":"4.4","Cell RNA - HL-60 [nTPM]":"0.7","Cell RNA - HMC-1 [nTPM]":"0.7","Cell RNA - HSkMC [nTPM]":"3.9","Cell RNA - hTCEpi [nTPM]":"13.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.4","Cell RNA - hTERT-RPE1 [nTPM]":"0.8","Cell RNA - HUVEC TERT2 [nTPM]":"2.9","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"0.6","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"7.1","Cell RNA - PC-3 [nTPM]":"0.6","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"5.9","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"2.1","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"28.0","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"2.4","Cell RNA - T-47d [nTPM]":"2.0","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"1.9","Cell RNA - U-138 MG [nTPM]":"0.6","Cell RNA - U-2 OS [nTPM]":"0.6","Cell RNA - U-2197 [nTPM]":"0.6","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"0.6","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"1.3","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"1.5","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"3.1","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"5.0","Brain RNA - basal ganglia [nTPM]":"4.5","Brain RNA - cerebellum [nTPM]":"6.4","Brain RNA - cerebral cortex [nTPM]":"6.3","Brain RNA - hippocampal formation [nTPM]":"4.5","Brain RNA - hypothalamus [nTPM]":"4.0","Brain RNA - medulla oblongata [nTPM]":"5.4","Brain RNA - midbrain [nTPM]":"4.8","Brain RNA - pons [nTPM]":"5.6","Brain RNA - spinal cord [nTPM]":"3.5","Brain RNA - thalamus [nTPM]":"5.8","Brain RNA - white matter [nTPM]":"4.7","Single Cell Type RNA - Adipocytes [nTPM]":"18.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.5","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"20.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"2.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"16.5","Single Cell Type RNA - Early spermatids [nTPM]":"8.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.9","Single Cell Type RNA - Endothelial cells [nTPM]":"25.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"3.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"33.2","Single Cell Type RNA - Hepatocytes [nTPM]":"137.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.4","Single Cell Type RNA - Langerhans cells [nTPM]":"0.9","Single Cell Type RNA - Late spermatids [nTPM]":"7.7","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"0.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"58.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"1.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"7.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.9","Single Cell Type RNA - Urothelial cells [nTPM]":"1.7"},{"Gene":"HYOU1","Gene synonym":["Grp170","HSP12A","ORP150"],"Ensembl":"ENSG00000149428","Gene description":"Hypoxia up-regulated 1","Uniprot":["Q9Y4L1"],"Chromosome":"11","Position":"119044188-119057227","Protein class":["Disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Stress response"],"Molecular function":["Chaperone"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"201.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"118.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"35.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"418.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049296"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"130000000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 65: Plasmacytoid DCs - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049296":"AB_2680702"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.58e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.10e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.00e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Tissue RNA - adipose tissue [nTPM]":"38.2","Tissue RNA - adrenal gland [nTPM]":"48.5","Tissue RNA - amygdala [nTPM]":"30.7","Tissue RNA - appendix [nTPM]":"27.1","Tissue RNA - basal ganglia [nTPM]":"32.2","Tissue RNA - bone marrow [nTPM]":"18.6","Tissue RNA - breast [nTPM]":"31.0","Tissue RNA - cerebellum [nTPM]":"28.3","Tissue RNA - cerebral cortex [nTPM]":"34.1","Tissue RNA - cervix [nTPM]":"37.2","Tissue RNA - choroid plexus [nTPM]":"25.5","Tissue RNA - colon [nTPM]":"40.9","Tissue RNA - duodenum [nTPM]":"18.1","Tissue RNA - endometrium 1 [nTPM]":"44.6","Tissue RNA - epididymis [nTPM]":"51.2","Tissue RNA - esophagus [nTPM]":"47.4","Tissue RNA - fallopian tube [nTPM]":"40.8","Tissue RNA - gallbladder [nTPM]":"14.0","Tissue RNA - heart muscle [nTPM]":"56.5","Tissue RNA - hippocampal formation [nTPM]":"32.9","Tissue RNA - hypothalamus [nTPM]":"41.0","Tissue RNA - kidney [nTPM]":"63.0","Tissue RNA - liver [nTPM]":"201.9","Tissue RNA - lung [nTPM]":"47.7","Tissue RNA - lymph node [nTPM]":"17.4","Tissue RNA - medulla oblongata [nTPM]":"32.6","Tissue RNA - midbrain [nTPM]":"34.5","Tissue RNA - ovary [nTPM]":"36.1","Tissue RNA - pancreas [nTPM]":"165.9","Tissue RNA - parathyroid gland [nTPM]":"18.8","Tissue RNA - pituitary gland [nTPM]":"100.1","Tissue RNA - placenta [nTPM]":"19.9","Tissue RNA - pons [nTPM]":"34.2","Tissue RNA - prostate [nTPM]":"47.9","Tissue RNA - rectum [nTPM]":"21.3","Tissue RNA - retina [nTPM]":"11.9","Tissue RNA - salivary gland [nTPM]":"46.3","Tissue RNA - seminal vesicle [nTPM]":"20.7","Tissue RNA - skeletal muscle [nTPM]":"19.1","Tissue RNA - skin 1 [nTPM]":"25.0","Tissue RNA - small intestine [nTPM]":"39.0","Tissue RNA - smooth muscle [nTPM]":"19.0","Tissue RNA - spinal cord [nTPM]":"28.5","Tissue RNA - spleen [nTPM]":"47.6","Tissue RNA - stomach 1 [nTPM]":"60.3","Tissue RNA - testis [nTPM]":"85.7","Tissue RNA - thalamus [nTPM]":"35.2","Tissue RNA - thymus [nTPM]":"21.7","Tissue RNA - thyroid gland [nTPM]":"87.2","Tissue RNA - tongue [nTPM]":"8.4","Tissue RNA - tonsil [nTPM]":"20.9","Tissue RNA - urinary bladder [nTPM]":"39.9","Tissue RNA - vagina [nTPM]":"31.7","Tissue RNA - white matter [nTPM]":"32.9","Cell RNA - A-431 [nTPM]":"40.5","Cell RNA - A549 [nTPM]":"34.5","Cell RNA - AF22 [nTPM]":"77.2","Cell RNA - AN3-CA [nTPM]":"224.4","Cell RNA - ASC diff [nTPM]":"41.2","Cell RNA - ASC TERT1 [nTPM]":"19.7","Cell RNA - BEWO [nTPM]":"107.7","Cell RNA - BJ [nTPM]":"56.1","Cell RNA - BJ hTERT+ [nTPM]":"38.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"63.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"47.2","Cell RNA - CACO-2 [nTPM]":"105.0","Cell RNA - CAPAN-2 [nTPM]":"103.0","Cell RNA - Daudi [nTPM]":"85.3","Cell RNA - EFO-21 [nTPM]":"418.9","Cell RNA - fHDF\/TERT166 [nTPM]":"40.7","Cell RNA - GAMG [nTPM]":"122.1","Cell RNA - HaCaT [nTPM]":"59.5","Cell RNA - HAP1 [nTPM]":"71.5","Cell RNA - HBEC3-KT [nTPM]":"69.3","Cell RNA - HBF TERT88 [nTPM]":"53.8","Cell RNA - HDLM-2 [nTPM]":"92.8","Cell RNA - HEK 293 [nTPM]":"26.1","Cell RNA - HEL [nTPM]":"151.8","Cell RNA - HeLa [nTPM]":"32.6","Cell RNA - Hep G2 [nTPM]":"76.7","Cell RNA - HHSteC [nTPM]":"187.7","Cell RNA - HL-60 [nTPM]":"88.6","Cell RNA - HMC-1 [nTPM]":"73.5","Cell RNA - HSkMC [nTPM]":"23.9","Cell RNA - hTCEpi [nTPM]":"91.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"55.2","Cell RNA - hTERT-HME1 [nTPM]":"185.3","Cell RNA - hTERT-RPE1 [nTPM]":"57.9","Cell RNA - HUVEC TERT2 [nTPM]":"100.2","Cell RNA - JURKAT [nTPM]":"57.2","Cell RNA - K-562 [nTPM]":"53.5","Cell RNA - Karpas-707 [nTPM]":"136.8","Cell RNA - LHCN-M2 [nTPM]":"33.9","Cell RNA - MCF7 [nTPM]":"97.8","Cell RNA - MOLT-4 [nTPM]":"59.4","Cell RNA - NB-4 [nTPM]":"49.6","Cell RNA - NTERA-2 [nTPM]":"55.5","Cell RNA - OE19 [nTPM]":"83.2","Cell RNA - PC-3 [nTPM]":"33.6","Cell RNA - REH [nTPM]":"63.1","Cell RNA - RH-30 [nTPM]":"55.9","Cell RNA - RPMI-8226 [nTPM]":"144.3","Cell RNA - RPTEC TERT1 [nTPM]":"48.6","Cell RNA - RT4 [nTPM]":"67.8","Cell RNA - SCLC-21H [nTPM]":"45.7","Cell RNA - SH-SY5Y [nTPM]":"70.0","Cell RNA - SiHa [nTPM]":"80.4","Cell RNA - SK-BR-3 [nTPM]":"103.8","Cell RNA - SK-MEL-30 [nTPM]":"53.3","Cell RNA - SuSa [nTPM]":"65.5","Cell RNA - T-47d [nTPM]":"78.8","Cell RNA - THP-1 [nTPM]":"82.9","Cell RNA - TIME [nTPM]":"75.0","Cell RNA - U-138 MG [nTPM]":"59.9","Cell RNA - U-2 OS [nTPM]":"46.4","Cell RNA - U-2197 [nTPM]":"27.2","Cell RNA - U-251 MG [nTPM]":"77.5","Cell RNA - U-266\/70 [nTPM]":"88.1","Cell RNA - U-266\/84 [nTPM]":"64.0","Cell RNA - U-698 [nTPM]":"61.2","Cell RNA - U-87 MG [nTPM]":"53.8","Cell RNA - U-937 [nTPM]":"76.2","Cell RNA - WM-115 [nTPM]":"135.6","Blood RNA - basophil [nTPM]":"4.4","Blood RNA - classical monocyte [nTPM]":"4.5","Blood RNA - eosinophil [nTPM]":"2.2","Blood RNA - gdT-cell [nTPM]":"11.7","Blood RNA - intermediate monocyte [nTPM]":"6.1","Blood RNA - MAIT T-cell [nTPM]":"12.6","Blood RNA - memory B-cell [nTPM]":"5.4","Blood RNA - memory CD4 T-cell [nTPM]":"6.4","Blood RNA - memory CD8 T-cell [nTPM]":"8.7","Blood RNA - myeloid DC [nTPM]":"5.0","Blood RNA - naive B-cell [nTPM]":"4.0","Blood RNA - naive CD4 T-cell [nTPM]":"4.0","Blood RNA - naive CD8 T-cell [nTPM]":"6.1","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"7.6","Blood RNA - non-classical monocyte [nTPM]":"4.4","Blood RNA - plasmacytoid DC [nTPM]":"35.9","Blood RNA - T-reg [nTPM]":"5.5","Blood RNA - total PBMC [nTPM]":"4.7","Brain RNA - amygdala [nTPM]":"30.7","Brain RNA - basal ganglia [nTPM]":"32.2","Brain RNA - cerebellum [nTPM]":"28.3","Brain RNA - cerebral cortex [nTPM]":"34.1","Brain RNA - hippocampal formation [nTPM]":"32.9","Brain RNA - hypothalamus [nTPM]":"41.0","Brain RNA - medulla oblongata [nTPM]":"32.6","Brain RNA - midbrain [nTPM]":"34.5","Brain RNA - pons [nTPM]":"34.2","Brain RNA - spinal cord [nTPM]":"28.5","Brain RNA - thalamus [nTPM]":"35.2","Brain RNA - white matter [nTPM]":"32.9","Single Cell Type RNA - Adipocytes [nTPM]":"16.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.1","Single Cell Type RNA - Astrocytes [nTPM]":"6.2","Single Cell Type RNA - B-cells [nTPM]":"22.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"11.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"28.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"16.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"43.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.2","Single Cell Type RNA - dendritic cells [nTPM]":"36.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"35.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"20.7","Single Cell Type RNA - Early spermatids [nTPM]":"74.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.1","Single Cell Type RNA - Endothelial cells [nTPM]":"20.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"35.8","Single Cell Type RNA - Erythroid cells [nTPM]":"17.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.6","Single Cell Type RNA - Fibroblasts [nTPM]":"21.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"39.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"38.1","Single Cell Type RNA - granulocytes [nTPM]":"15.8","Single Cell Type RNA - Granulosa cells [nTPM]":"43.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.9","Single Cell Type RNA - Hepatocytes [nTPM]":"49.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.2","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"52.1","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"8.2","Single Cell Type RNA - Langerhans cells [nTPM]":"21.6","Single Cell Type RNA - Late spermatids [nTPM]":"38.8","Single Cell Type RNA - Leydig cells [nTPM]":"13.1","Single Cell Type RNA - Macrophages [nTPM]":"17.8","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"15.5","Single Cell Type RNA - Muller glia cells [nTPM]":"8.7","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"31.4","Single Cell Type RNA - Paneth cells [nTPM]":"24.2","Single Cell Type RNA - Peritubular cells [nTPM]":"13.5","Single Cell Type RNA - Plasma cells [nTPM]":"118.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"44.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.6","Single Cell Type RNA - Spermatocytes [nTPM]":"27.8","Single Cell Type RNA - Spermatogonia [nTPM]":"29.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"19.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"19.3","Single Cell Type RNA - T-cells [nTPM]":"20.8","Single Cell Type RNA - Theca cells [nTPM]":"14.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"27.3","Single Cell Type RNA - Urothelial cells [nTPM]":"24.7"},{"Gene":"IARS1","Gene synonym":["IARS","ILRS"],"Ensembl":"ENSG00000196305","Gene description":"Isoleucyl-tRNA synthetase 1","Uniprot":["P41252"],"Chromosome":"9","Position":"92210207-92293756","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"47.6","Cytotrophoblasts":"29.8","Extravillous trophoblasts":"31.7","Hofbauer cells":"17.2","Syncytiotrophoblasts":"17.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029806"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"100000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA029806":"AB_10601818"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.98e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-3"},"Tissue RNA - adipose tissue [nTPM]":"22.2","Tissue RNA - adrenal gland [nTPM]":"24.3","Tissue RNA - amygdala [nTPM]":"6.3","Tissue RNA - appendix [nTPM]":"28.8","Tissue RNA - basal ganglia [nTPM]":"5.8","Tissue RNA - bone marrow [nTPM]":"13.2","Tissue RNA - breast [nTPM]":"27.4","Tissue RNA - cerebellum [nTPM]":"8.8","Tissue RNA - cerebral cortex [nTPM]":"11.5","Tissue RNA - cervix [nTPM]":"26.4","Tissue RNA - choroid plexus [nTPM]":"10.7","Tissue RNA - colon [nTPM]":"29.1","Tissue RNA - duodenum [nTPM]":"17.9","Tissue RNA - endometrium 1 [nTPM]":"32.5","Tissue RNA - epididymis [nTPM]":"15.1","Tissue RNA - esophagus [nTPM]":"31.8","Tissue RNA - fallopian tube [nTPM]":"27.7","Tissue RNA - gallbladder [nTPM]":"16.1","Tissue RNA - heart muscle [nTPM]":"32.2","Tissue RNA - hippocampal formation [nTPM]":"6.8","Tissue RNA - hypothalamus [nTPM]":"10.7","Tissue RNA - kidney [nTPM]":"28.4","Tissue RNA - liver [nTPM]":"19.6","Tissue RNA - lung [nTPM]":"18.9","Tissue RNA - lymph node [nTPM]":"28.3","Tissue RNA - medulla oblongata [nTPM]":"5.9","Tissue RNA - midbrain [nTPM]":"7.3","Tissue RNA - ovary [nTPM]":"20.4","Tissue RNA - pancreas [nTPM]":"40.1","Tissue RNA - parathyroid gland [nTPM]":"52.3","Tissue RNA - pituitary gland [nTPM]":"11.7","Tissue RNA - placenta [nTPM]":"27.7","Tissue RNA - pons [nTPM]":"8.6","Tissue RNA - prostate [nTPM]":"27.7","Tissue RNA - rectum [nTPM]":"33.3","Tissue RNA - retina [nTPM]":"25.2","Tissue RNA - salivary gland [nTPM]":"25.5","Tissue RNA - seminal vesicle [nTPM]":"31.6","Tissue RNA - skeletal muscle [nTPM]":"43.1","Tissue RNA - skin 1 [nTPM]":"21.7","Tissue RNA - small intestine [nTPM]":"16.2","Tissue RNA - smooth muscle [nTPM]":"42.6","Tissue RNA - spinal cord [nTPM]":"3.6","Tissue RNA - spleen [nTPM]":"19.7","Tissue RNA - stomach 1 [nTPM]":"31.4","Tissue RNA - testis [nTPM]":"20.0","Tissue RNA - thalamus [nTPM]":"5.2","Tissue RNA - thymus [nTPM]":"27.5","Tissue RNA - thyroid gland [nTPM]":"64.6","Tissue RNA - tongue [nTPM]":"47.2","Tissue RNA - tonsil [nTPM]":"37.6","Tissue RNA - urinary bladder [nTPM]":"28.2","Tissue RNA - vagina [nTPM]":"11.7","Tissue RNA - white matter [nTPM]":"6.9","Cell RNA - A-431 [nTPM]":"150.7","Cell RNA - A549 [nTPM]":"154.9","Cell RNA - AF22 [nTPM]":"83.3","Cell RNA - AN3-CA [nTPM]":"132.2","Cell RNA - ASC diff [nTPM]":"110.5","Cell RNA - ASC TERT1 [nTPM]":"142.2","Cell RNA - BEWO [nTPM]":"126.8","Cell RNA - BJ [nTPM]":"156.4","Cell RNA - BJ hTERT+ [nTPM]":"146.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"118.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"138.5","Cell RNA - CACO-2 [nTPM]":"52.2","Cell RNA - CAPAN-2 [nTPM]":"99.0","Cell RNA - Daudi [nTPM]":"216.0","Cell RNA - EFO-21 [nTPM]":"54.9","Cell RNA - fHDF\/TERT166 [nTPM]":"231.4","Cell RNA - GAMG [nTPM]":"130.5","Cell RNA - HaCaT [nTPM]":"194.9","Cell RNA - HAP1 [nTPM]":"254.4","Cell RNA - HBEC3-KT [nTPM]":"197.9","Cell RNA - HBF TERT88 [nTPM]":"149.3","Cell RNA - HDLM-2 [nTPM]":"126.1","Cell RNA - HEK 293 [nTPM]":"97.9","Cell RNA - HEL [nTPM]":"135.3","Cell RNA - HeLa [nTPM]":"128.3","Cell RNA - Hep G2 [nTPM]":"62.8","Cell RNA - HHSteC [nTPM]":"235.6","Cell RNA - HL-60 [nTPM]":"181.3","Cell RNA - HMC-1 [nTPM]":"90.6","Cell RNA - HSkMC [nTPM]":"134.1","Cell RNA - hTCEpi [nTPM]":"194.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"208.9","Cell RNA - hTERT-HME1 [nTPM]":"348.9","Cell RNA - hTERT-RPE1 [nTPM]":"78.3","Cell RNA - HUVEC TERT2 [nTPM]":"123.6","Cell RNA - JURKAT [nTPM]":"230.1","Cell RNA - K-562 [nTPM]":"229.2","Cell RNA - Karpas-707 [nTPM]":"189.8","Cell RNA - LHCN-M2 [nTPM]":"145.0","Cell RNA - MCF7 [nTPM]":"79.3","Cell RNA - MOLT-4 [nTPM]":"173.2","Cell RNA - NB-4 [nTPM]":"31.6","Cell RNA - NTERA-2 [nTPM]":"139.7","Cell RNA - OE19 [nTPM]":"294.5","Cell RNA - PC-3 [nTPM]":"143.3","Cell RNA - REH [nTPM]":"116.2","Cell RNA - RH-30 [nTPM]":"129.3","Cell RNA - RPMI-8226 [nTPM]":"103.0","Cell RNA - RPTEC TERT1 [nTPM]":"72.9","Cell RNA - RT4 [nTPM]":"72.6","Cell RNA - SCLC-21H [nTPM]":"110.2","Cell RNA - SH-SY5Y [nTPM]":"91.5","Cell RNA - SiHa [nTPM]":"118.2","Cell RNA - SK-BR-3 [nTPM]":"117.0","Cell RNA - SK-MEL-30 [nTPM]":"128.8","Cell RNA - SuSa [nTPM]":"87.8","Cell RNA - T-47d [nTPM]":"95.2","Cell RNA - THP-1 [nTPM]":"94.4","Cell RNA - TIME [nTPM]":"101.3","Cell RNA - U-138 MG [nTPM]":"89.5","Cell RNA - U-2 OS [nTPM]":"104.6","Cell RNA - U-2197 [nTPM]":"149.3","Cell RNA - U-251 MG [nTPM]":"119.1","Cell RNA - U-266\/70 [nTPM]":"134.8","Cell RNA - U-266\/84 [nTPM]":"156.4","Cell RNA - U-698 [nTPM]":"99.5","Cell RNA - U-87 MG [nTPM]":"218.7","Cell RNA - U-937 [nTPM]":"133.3","Cell RNA - WM-115 [nTPM]":"173.3","Blood RNA - basophil [nTPM]":"2.8","Blood RNA - classical monocyte [nTPM]":"5.9","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"11.9","Blood RNA - intermediate monocyte [nTPM]":"7.0","Blood RNA - MAIT T-cell [nTPM]":"16.4","Blood RNA - memory B-cell [nTPM]":"13.9","Blood RNA - memory CD4 T-cell [nTPM]":"11.8","Blood RNA - memory CD8 T-cell [nTPM]":"11.9","Blood RNA - myeloid DC [nTPM]":"12.7","Blood RNA - naive B-cell [nTPM]":"9.7","Blood RNA - naive CD4 T-cell [nTPM]":"12.8","Blood RNA - naive CD8 T-cell [nTPM]":"12.7","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"19.5","Blood RNA - non-classical monocyte [nTPM]":"6.3","Blood RNA - plasmacytoid DC [nTPM]":"4.8","Blood RNA - T-reg [nTPM]":"10.9","Blood RNA - total PBMC [nTPM]":"9.0","Brain RNA - amygdala [nTPM]":"6.3","Brain RNA - basal ganglia [nTPM]":"5.8","Brain RNA - cerebellum [nTPM]":"8.8","Brain RNA - cerebral cortex [nTPM]":"11.5","Brain RNA - hippocampal formation [nTPM]":"6.8","Brain RNA - hypothalamus [nTPM]":"10.7","Brain RNA - medulla oblongata [nTPM]":"5.9","Brain RNA - midbrain [nTPM]":"7.3","Brain RNA - pons [nTPM]":"8.6","Brain RNA - spinal cord [nTPM]":"3.6","Brain RNA - thalamus [nTPM]":"5.2","Brain RNA - white matter [nTPM]":"6.9","Single Cell Type RNA - Adipocytes [nTPM]":"7.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"47.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"29.8","Single Cell Type RNA - dendritic cells [nTPM]":"7.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"2.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"31.7","Single Cell Type RNA - Fibroblasts [nTPM]":"8.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"4.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.4","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"IARS2","Gene synonym":["FLJ10326"],"Ensembl":"ENSG00000067704","Gene description":"Isoleucyl-tRNA synthetase 2, mitochondrial","Uniprot":["Q9NSE4"],"Chromosome":"1","Position":"220094132-220148041","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Cataract","Deafness","Disease variant","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024212","HPA024594","HPA024596"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"35000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA024212":"AB_1851363","HPA024594":"AB_1851368","HPA024596":"AB_1851370"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.04e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.24e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-3"},"Tissue RNA - adipose tissue [nTPM]":"55.8","Tissue RNA - adrenal gland [nTPM]":"49.8","Tissue RNA - amygdala [nTPM]":"19.9","Tissue RNA - appendix [nTPM]":"33.3","Tissue RNA - basal ganglia [nTPM]":"21.1","Tissue RNA - bone marrow [nTPM]":"18.3","Tissue RNA - breast [nTPM]":"41.8","Tissue RNA - cerebellum [nTPM]":"23.5","Tissue RNA - cerebral cortex [nTPM]":"25.4","Tissue RNA - cervix [nTPM]":"35.3","Tissue RNA - choroid plexus [nTPM]":"37.8","Tissue RNA - colon [nTPM]":"54.2","Tissue RNA - duodenum [nTPM]":"43.4","Tissue RNA - endometrium 1 [nTPM]":"31.8","Tissue RNA - epididymis [nTPM]":"31.4","Tissue RNA - esophagus [nTPM]":"47.9","Tissue RNA - fallopian tube [nTPM]":"41.4","Tissue RNA - gallbladder [nTPM]":"30.5","Tissue RNA - heart muscle [nTPM]":"60.0","Tissue RNA - hippocampal formation [nTPM]":"20.0","Tissue RNA - hypothalamus [nTPM]":"21.8","Tissue RNA - kidney [nTPM]":"65.5","Tissue RNA - liver [nTPM]":"83.8","Tissue RNA - lung [nTPM]":"31.0","Tissue RNA - lymph node [nTPM]":"38.8","Tissue RNA - medulla oblongata [nTPM]":"22.7","Tissue RNA - midbrain [nTPM]":"22.2","Tissue RNA - ovary [nTPM]":"39.0","Tissue RNA - pancreas [nTPM]":"33.6","Tissue RNA - parathyroid gland [nTPM]":"80.5","Tissue RNA - pituitary gland [nTPM]":"16.0","Tissue RNA - placenta [nTPM]":"40.7","Tissue RNA - pons [nTPM]":"25.0","Tissue RNA - prostate [nTPM]":"36.1","Tissue RNA - rectum [nTPM]":"54.8","Tissue RNA - retina [nTPM]":"34.8","Tissue RNA - salivary gland [nTPM]":"40.0","Tissue RNA - seminal vesicle [nTPM]":"37.5","Tissue RNA - skeletal muscle [nTPM]":"92.9","Tissue RNA - skin 1 [nTPM]":"40.5","Tissue RNA - small intestine [nTPM]":"40.4","Tissue RNA - smooth muscle [nTPM]":"39.4","Tissue RNA - spinal cord [nTPM]":"21.6","Tissue RNA - spleen [nTPM]":"28.4","Tissue RNA - stomach 1 [nTPM]":"39.1","Tissue RNA - testis [nTPM]":"30.1","Tissue RNA - thalamus [nTPM]":"22.3","Tissue RNA - thymus [nTPM]":"31.8","Tissue RNA - thyroid gland [nTPM]":"39.7","Tissue RNA - tongue [nTPM]":"85.7","Tissue RNA - tonsil [nTPM]":"43.1","Tissue RNA - urinary bladder [nTPM]":"35.6","Tissue RNA - vagina [nTPM]":"30.0","Tissue RNA - white matter [nTPM]":"22.9","Cell RNA - A-431 [nTPM]":"137.2","Cell RNA - A549 [nTPM]":"125.6","Cell RNA - AF22 [nTPM]":"70.7","Cell RNA - AN3-CA [nTPM]":"69.9","Cell RNA - ASC diff [nTPM]":"104.2","Cell RNA - ASC TERT1 [nTPM]":"104.4","Cell RNA - BEWO [nTPM]":"169.6","Cell RNA - BJ [nTPM]":"81.4","Cell RNA - BJ hTERT+ [nTPM]":"86.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"87.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"70.7","Cell RNA - CACO-2 [nTPM]":"121.7","Cell RNA - CAPAN-2 [nTPM]":"138.8","Cell RNA - Daudi [nTPM]":"125.6","Cell RNA - EFO-21 [nTPM]":"107.1","Cell RNA - fHDF\/TERT166 [nTPM]":"101.4","Cell RNA - GAMG [nTPM]":"68.0","Cell RNA - HaCaT [nTPM]":"129.3","Cell RNA - HAP1 [nTPM]":"99.0","Cell RNA - HBEC3-KT [nTPM]":"101.5","Cell RNA - HBF TERT88 [nTPM]":"100.9","Cell RNA - HDLM-2 [nTPM]":"87.5","Cell RNA - HEK 293 [nTPM]":"119.3","Cell RNA - HEL [nTPM]":"62.6","Cell RNA - HeLa [nTPM]":"94.6","Cell RNA - Hep G2 [nTPM]":"137.8","Cell RNA - HHSteC [nTPM]":"64.6","Cell RNA - HL-60 [nTPM]":"100.4","Cell RNA - HMC-1 [nTPM]":"64.9","Cell RNA - HSkMC [nTPM]":"76.0","Cell RNA - hTCEpi [nTPM]":"101.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"95.4","Cell RNA - hTERT-HME1 [nTPM]":"97.6","Cell RNA - hTERT-RPE1 [nTPM]":"84.7","Cell RNA - HUVEC TERT2 [nTPM]":"86.9","Cell RNA - JURKAT [nTPM]":"79.9","Cell RNA - K-562 [nTPM]":"156.9","Cell RNA - Karpas-707 [nTPM]":"70.7","Cell RNA - LHCN-M2 [nTPM]":"116.7","Cell RNA - MCF7 [nTPM]":"75.9","Cell RNA - MOLT-4 [nTPM]":"79.8","Cell RNA - NB-4 [nTPM]":"72.0","Cell RNA - NTERA-2 [nTPM]":"92.1","Cell RNA - OE19 [nTPM]":"106.2","Cell RNA - PC-3 [nTPM]":"82.1","Cell RNA - REH [nTPM]":"69.5","Cell RNA - RH-30 [nTPM]":"140.7","Cell RNA - RPMI-8226 [nTPM]":"202.2","Cell RNA - RPTEC TERT1 [nTPM]":"126.2","Cell RNA - RT4 [nTPM]":"90.4","Cell RNA - SCLC-21H [nTPM]":"38.0","Cell RNA - SH-SY5Y [nTPM]":"106.6","Cell RNA - SiHa [nTPM]":"123.2","Cell RNA - SK-BR-3 [nTPM]":"188.2","Cell RNA - SK-MEL-30 [nTPM]":"130.3","Cell RNA - SuSa [nTPM]":"80.6","Cell RNA - T-47d [nTPM]":"218.5","Cell RNA - THP-1 [nTPM]":"111.9","Cell RNA - TIME [nTPM]":"89.8","Cell RNA - U-138 MG [nTPM]":"86.1","Cell RNA - U-2 OS [nTPM]":"71.6","Cell RNA - U-2197 [nTPM]":"117.0","Cell RNA - U-251 MG [nTPM]":"138.4","Cell RNA - U-266\/70 [nTPM]":"60.0","Cell RNA - U-266\/84 [nTPM]":"98.9","Cell RNA - U-698 [nTPM]":"90.8","Cell RNA - U-87 MG [nTPM]":"91.3","Cell RNA - U-937 [nTPM]":"77.3","Cell RNA - WM-115 [nTPM]":"97.6","Blood RNA - basophil [nTPM]":"33.8","Blood RNA - classical monocyte [nTPM]":"24.6","Blood RNA - eosinophil [nTPM]":"22.8","Blood RNA - gdT-cell [nTPM]":"23.0","Blood RNA - intermediate monocyte [nTPM]":"27.7","Blood RNA - MAIT T-cell [nTPM]":"30.8","Blood RNA - memory B-cell [nTPM]":"23.6","Blood RNA - memory CD4 T-cell [nTPM]":"24.9","Blood RNA - memory CD8 T-cell [nTPM]":"30.3","Blood RNA - myeloid DC [nTPM]":"29.2","Blood RNA - naive B-cell [nTPM]":"18.3","Blood RNA - naive CD4 T-cell [nTPM]":"27.8","Blood RNA - naive CD8 T-cell [nTPM]":"25.6","Blood RNA - neutrophil [nTPM]":"4.7","Blood RNA - NK-cell [nTPM]":"28.3","Blood RNA - non-classical monocyte [nTPM]":"22.3","Blood RNA - plasmacytoid DC [nTPM]":"10.6","Blood RNA - T-reg [nTPM]":"29.9","Blood RNA - total PBMC [nTPM]":"26.7","Brain RNA - amygdala [nTPM]":"19.9","Brain RNA - basal ganglia [nTPM]":"21.1","Brain RNA - cerebellum [nTPM]":"23.5","Brain RNA - cerebral cortex [nTPM]":"25.4","Brain RNA - hippocampal formation [nTPM]":"20.0","Brain RNA - hypothalamus [nTPM]":"21.8","Brain RNA - medulla oblongata [nTPM]":"22.7","Brain RNA - midbrain [nTPM]":"22.2","Brain RNA - pons [nTPM]":"25.0","Brain RNA - spinal cord [nTPM]":"21.6","Brain RNA - thalamus [nTPM]":"22.3","Brain RNA - white matter [nTPM]":"22.9","Single Cell Type RNA - Adipocytes [nTPM]":"66.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"38.0","Single Cell Type RNA - Astrocytes [nTPM]":"15.7","Single Cell Type RNA - B-cells [nTPM]":"30.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"28.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"44.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"34.7","Single Cell Type RNA - Bipolar cells [nTPM]":"28.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"40.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"39.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"144.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"42.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"79.0","Single Cell Type RNA - dendritic cells [nTPM]":"31.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"54.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"47.7","Single Cell Type RNA - Early spermatids [nTPM]":"20.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"63.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"48.3","Single Cell Type RNA - Endothelial cells [nTPM]":"43.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"36.2","Single Cell Type RNA - Erythroid cells [nTPM]":"29.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"65.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"55.5","Single Cell Type RNA - Fibroblasts [nTPM]":"37.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"44.3","Single Cell Type RNA - granulocytes [nTPM]":"19.6","Single Cell Type RNA - Granulosa cells [nTPM]":"41.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"37.5","Single Cell Type RNA - Hepatocytes [nTPM]":"99.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"45.9","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"55.4","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"51.0","Single Cell Type RNA - Langerhans cells [nTPM]":"11.2","Single Cell Type RNA - Late spermatids [nTPM]":"6.8","Single Cell Type RNA - Leydig cells [nTPM]":"37.3","Single Cell Type RNA - Macrophages [nTPM]":"35.9","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"46.1","Single Cell Type RNA - Muller glia cells [nTPM]":"34.6","Single Cell Type RNA - NK-cells [nTPM]":"27.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"31.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"67.4","Single Cell Type RNA - Paneth cells [nTPM]":"44.9","Single Cell Type RNA - Peritubular cells [nTPM]":"42.5","Single Cell Type RNA - Plasma cells [nTPM]":"33.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"34.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"38.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"36.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"62.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"46.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"39.0","Single Cell Type RNA - Spermatocytes [nTPM]":"44.6","Single Cell Type RNA - Spermatogonia [nTPM]":"44.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"63.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"26.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"71.7","Single Cell Type RNA - T-cells [nTPM]":"31.0","Single Cell Type RNA - Theca cells [nTPM]":"54.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"69.9","Single Cell Type RNA - Urothelial cells [nTPM]":"27.6"},{"Gene":"IDS","Gene synonym":["ID2S","SIDS"],"Ensembl":"ENSG00000010404","Gene description":"Iduronate 2-sulfatase","Uniprot":["P22304"],"Chromosome":"X","Position":"149476988-149521096","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Mucopolysaccharidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"323.4"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"amygdala":"194.3","basal ganglia":"212.9","cerebral cortex":"323.4","hippocampal formation":"320.5","white matter":"109.4"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078003"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"17000000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA078003":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Tissue RNA - adipose tissue [nTPM]":"32.7","Tissue RNA - adrenal gland [nTPM]":"43.3","Tissue RNA - amygdala [nTPM]":"194.3","Tissue RNA - appendix [nTPM]":"29.5","Tissue RNA - basal ganglia [nTPM]":"212.9","Tissue RNA - bone marrow [nTPM]":"47.6","Tissue RNA - breast [nTPM]":"27.9","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"323.4","Tissue RNA - cervix [nTPM]":"37.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"35.7","Tissue RNA - duodenum [nTPM]":"21.1","Tissue RNA - endometrium 1 [nTPM]":"35.1","Tissue RNA - epididymis [nTPM]":"43.5","Tissue RNA - esophagus [nTPM]":"26.1","Tissue RNA - fallopian tube [nTPM]":"35.7","Tissue RNA - gallbladder [nTPM]":"26.3","Tissue RNA - heart muscle [nTPM]":"42.2","Tissue RNA - hippocampal formation [nTPM]":"320.5","Tissue RNA - hypothalamus [nTPM]":"25.7","Tissue RNA - kidney [nTPM]":"22.7","Tissue RNA - liver [nTPM]":"15.8","Tissue RNA - lung [nTPM]":"40.5","Tissue RNA - lymph node [nTPM]":"31.0","Tissue RNA - medulla oblongata [nTPM]":"9.7","Tissue RNA - midbrain [nTPM]":"9.4","Tissue RNA - ovary [nTPM]":"45.4","Tissue RNA - pancreas [nTPM]":"23.3","Tissue RNA - parathyroid gland [nTPM]":"57.0","Tissue RNA - pituitary gland [nTPM]":"67.8","Tissue RNA - placenta [nTPM]":"16.3","Tissue RNA - pons [nTPM]":"3.1","Tissue RNA - prostate [nTPM]":"29.4","Tissue RNA - rectum [nTPM]":"20.8","Tissue RNA - retina [nTPM]":"48.6","Tissue RNA - salivary gland [nTPM]":"24.7","Tissue RNA - seminal vesicle [nTPM]":"41.0","Tissue RNA - skeletal muscle [nTPM]":"25.1","Tissue RNA - skin 1 [nTPM]":"37.1","Tissue RNA - small intestine [nTPM]":"27.9","Tissue RNA - smooth muscle [nTPM]":"30.5","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"34.1","Tissue RNA - stomach 1 [nTPM]":"23.0","Tissue RNA - testis [nTPM]":"6.1","Tissue RNA - thalamus [nTPM]":"32.3","Tissue RNA - thymus [nTPM]":"17.2","Tissue RNA - thyroid gland [nTPM]":"27.2","Tissue RNA - tongue [nTPM]":"38.9","Tissue RNA - tonsil [nTPM]":"36.0","Tissue RNA - urinary bladder [nTPM]":"32.8","Tissue RNA - vagina [nTPM]":"31.5","Tissue RNA - white matter [nTPM]":"109.4","Cell RNA - A-431 [nTPM]":"46.4","Cell RNA - A549 [nTPM]":"50.7","Cell RNA - AF22 [nTPM]":"19.6","Cell RNA - AN3-CA [nTPM]":"12.7","Cell RNA - ASC diff [nTPM]":"22.1","Cell RNA - ASC TERT1 [nTPM]":"40.9","Cell RNA - BEWO [nTPM]":"9.2","Cell RNA - BJ [nTPM]":"26.6","Cell RNA - BJ hTERT+ [nTPM]":"67.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"43.9","Cell RNA - CACO-2 [nTPM]":"10.2","Cell RNA - CAPAN-2 [nTPM]":"32.7","Cell RNA - Daudi [nTPM]":"110.0","Cell RNA - EFO-21 [nTPM]":"69.6","Cell RNA - fHDF\/TERT166 [nTPM]":"38.3","Cell RNA - GAMG [nTPM]":"49.1","Cell RNA - HaCaT [nTPM]":"22.6","Cell RNA - HAP1 [nTPM]":"21.3","Cell RNA - HBEC3-KT [nTPM]":"40.5","Cell RNA - HBF TERT88 [nTPM]":"30.1","Cell RNA - HDLM-2 [nTPM]":"40.8","Cell RNA - HEK 293 [nTPM]":"17.7","Cell RNA - HEL [nTPM]":"11.5","Cell RNA - HeLa [nTPM]":"14.7","Cell RNA - Hep G2 [nTPM]":"5.7","Cell RNA - HHSteC [nTPM]":"17.8","Cell RNA - HL-60 [nTPM]":"18.8","Cell RNA - HMC-1 [nTPM]":"101.3","Cell RNA - HSkMC [nTPM]":"21.4","Cell RNA - hTCEpi [nTPM]":"19.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"50.9","Cell RNA - hTERT-HME1 [nTPM]":"33.1","Cell RNA - hTERT-RPE1 [nTPM]":"95.5","Cell RNA - HUVEC TERT2 [nTPM]":"37.8","Cell RNA - JURKAT [nTPM]":"20.2","Cell RNA - K-562 [nTPM]":"5.7","Cell RNA - Karpas-707 [nTPM]":"76.6","Cell RNA - LHCN-M2 [nTPM]":"34.7","Cell RNA - MCF7 [nTPM]":"57.9","Cell RNA - MOLT-4 [nTPM]":"19.6","Cell RNA - NB-4 [nTPM]":"9.3","Cell RNA - NTERA-2 [nTPM]":"17.5","Cell RNA - OE19 [nTPM]":"28.8","Cell RNA - PC-3 [nTPM]":"34.3","Cell RNA - REH [nTPM]":"12.4","Cell RNA - RH-30 [nTPM]":"19.4","Cell RNA - RPMI-8226 [nTPM]":"20.7","Cell RNA - RPTEC TERT1 [nTPM]":"27.8","Cell RNA - RT4 [nTPM]":"10.5","Cell RNA - SCLC-21H [nTPM]":"28.9","Cell RNA - SH-SY5Y [nTPM]":"67.6","Cell RNA - SiHa [nTPM]":"9.8","Cell RNA - SK-BR-3 [nTPM]":"22.1","Cell RNA - SK-MEL-30 [nTPM]":"32.0","Cell RNA - SuSa [nTPM]":"33.2","Cell RNA - T-47d [nTPM]":"6.9","Cell RNA - THP-1 [nTPM]":"7.9","Cell RNA - TIME [nTPM]":"44.3","Cell RNA - U-138 MG [nTPM]":"29.9","Cell RNA - U-2 OS [nTPM]":"31.3","Cell RNA - U-2197 [nTPM]":"50.1","Cell RNA - U-251 MG [nTPM]":"70.8","Cell RNA - U-266\/70 [nTPM]":"54.5","Cell RNA - U-266\/84 [nTPM]":"47.3","Cell RNA - U-698 [nTPM]":"79.3","Cell RNA - U-87 MG [nTPM]":"138.0","Cell RNA - U-937 [nTPM]":"44.3","Cell RNA - WM-115 [nTPM]":"22.1","Blood RNA - basophil [nTPM]":"117.5","Blood RNA - classical monocyte [nTPM]":"56.9","Blood RNA - eosinophil [nTPM]":"171.7","Blood RNA - gdT-cell [nTPM]":"70.9","Blood RNA - intermediate monocyte [nTPM]":"63.0","Blood RNA - MAIT T-cell [nTPM]":"53.2","Blood RNA - memory B-cell [nTPM]":"35.2","Blood RNA - memory CD4 T-cell [nTPM]":"43.1","Blood RNA - memory CD8 T-cell [nTPM]":"54.0","Blood RNA - myeloid DC [nTPM]":"48.7","Blood RNA - naive B-cell [nTPM]":"27.0","Blood RNA - naive CD4 T-cell [nTPM]":"28.4","Blood RNA - naive CD8 T-cell [nTPM]":"42.9","Blood RNA - neutrophil [nTPM]":"261.1","Blood RNA - NK-cell [nTPM]":"37.2","Blood RNA - non-classical monocyte [nTPM]":"73.9","Blood RNA - plasmacytoid DC [nTPM]":"36.8","Blood RNA - T-reg [nTPM]":"74.0","Blood RNA - total PBMC [nTPM]":"63.0","Brain RNA - amygdala [nTPM]":"194.3","Brain RNA - basal ganglia [nTPM]":"212.9","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"323.4","Brain RNA - hippocampal formation [nTPM]":"320.5","Brain RNA - hypothalamus [nTPM]":"25.7","Brain RNA - medulla oblongata [nTPM]":"9.7","Brain RNA - midbrain [nTPM]":"9.4","Brain RNA - pons [nTPM]":"3.1","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"32.3","Brain RNA - white matter [nTPM]":"109.4","Single Cell Type RNA - Adipocytes [nTPM]":"53.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"99.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"64.4","Single Cell Type RNA - Astrocytes [nTPM]":"55.8","Single Cell Type RNA - B-cells [nTPM]":"150.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"33.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"60.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"44.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"20.5","Single Cell Type RNA - Bipolar cells [nTPM]":"178.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"43.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"43.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"44.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"58.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"82.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"34.2","Single Cell Type RNA - dendritic cells [nTPM]":"158.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"66.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"50.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"59.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"36.8","Single Cell Type RNA - Endothelial cells [nTPM]":"44.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"168.4","Single Cell Type RNA - Erythroid cells [nTPM]":"19.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"232.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"74.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"25.7","Single Cell Type RNA - Fibroblasts [nTPM]":"78.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"31.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"49.5","Single Cell Type RNA - granulocytes [nTPM]":"226.2","Single Cell Type RNA - Granulosa cells [nTPM]":"25.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"60.3","Single Cell Type RNA - Hepatocytes [nTPM]":"33.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"44.0","Single Cell Type RNA - Horizontal cells [nTPM]":"222.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"243.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"29.0","Single Cell Type RNA - Ionocytes [nTPM]":"73.2","Single Cell Type RNA - Kupffer cells [nTPM]":"94.8","Single Cell Type RNA - Langerhans cells [nTPM]":"109.8","Single Cell Type RNA - Late spermatids [nTPM]":"3.7","Single Cell Type RNA - Leydig cells [nTPM]":"72.7","Single Cell Type RNA - Macrophages [nTPM]":"98.4","Single Cell Type RNA - Melanocytes [nTPM]":"51.6","Single Cell Type RNA - Microglial cells [nTPM]":"63.7","Single Cell Type RNA - monocytes [nTPM]":"120.9","Single Cell Type RNA - Muller glia cells [nTPM]":"55.0","Single Cell Type RNA - NK-cells [nTPM]":"146.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"39.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"95.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"85.0","Single Cell Type RNA - Paneth cells [nTPM]":"50.3","Single Cell Type RNA - Peritubular cells [nTPM]":"89.5","Single Cell Type RNA - Plasma cells [nTPM]":"98.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"71.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"74.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"112.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"59.5","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"68.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"65.2","Single Cell Type RNA - Spermatocytes [nTPM]":"3.5","Single Cell Type RNA - Spermatogonia [nTPM]":"6.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"43.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"143.0","Single Cell Type RNA - T-cells [nTPM]":"183.9","Single Cell Type RNA - Theca cells [nTPM]":"16.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.1","Single Cell Type RNA - Urothelial cells [nTPM]":"96.9"},{"Gene":"IDUA","Gene synonym":["MPS1","MPSI"],"Ensembl":"ENSG00000127415","Gene description":"Alpha-L-iduronidase","Uniprot":["P35475"],"Chromosome":"4","Position":"986997-1004564","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant","Mucopolysaccharidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Leydig cells":"19.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-266\/70":"29.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025901","HPA046979","HPA054254"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB025901":null,"HPA046979":"AB_2679888","HPA054254":"AB_2682429"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.13e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.87e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.04e-5"},"Tissue RNA - adipose tissue [nTPM]":"13.5","Tissue RNA - adrenal gland [nTPM]":"17.6","Tissue RNA - amygdala [nTPM]":"3.4","Tissue RNA - appendix [nTPM]":"2.2","Tissue RNA - basal ganglia [nTPM]":"3.4","Tissue RNA - bone marrow [nTPM]":"2.9","Tissue RNA - breast [nTPM]":"16.1","Tissue RNA - cerebellum [nTPM]":"9.2","Tissue RNA - cerebral cortex [nTPM]":"7.5","Tissue RNA - cervix [nTPM]":"17.5","Tissue RNA - choroid plexus [nTPM]":"2.9","Tissue RNA - colon [nTPM]":"10.3","Tissue RNA - duodenum [nTPM]":"3.6","Tissue RNA - endometrium 1 [nTPM]":"15.4","Tissue RNA - epididymis [nTPM]":"2.4","Tissue RNA - esophagus [nTPM]":"9.9","Tissue RNA - fallopian tube [nTPM]":"16.3","Tissue RNA - gallbladder [nTPM]":"3.7","Tissue RNA - heart muscle [nTPM]":"11.6","Tissue RNA - hippocampal formation [nTPM]":"3.8","Tissue RNA - hypothalamus [nTPM]":"1.5","Tissue RNA - kidney [nTPM]":"15.9","Tissue RNA - liver [nTPM]":"13.6","Tissue RNA - lung [nTPM]":"13.9","Tissue RNA - lymph node [nTPM]":"3.5","Tissue RNA - medulla oblongata [nTPM]":"3.2","Tissue RNA - midbrain [nTPM]":"2.1","Tissue RNA - ovary [nTPM]":"17.0","Tissue RNA - pancreas [nTPM]":"21.0","Tissue RNA - parathyroid gland [nTPM]":"2.8","Tissue RNA - pituitary gland [nTPM]":"17.2","Tissue RNA - placenta [nTPM]":"1.7","Tissue RNA - pons [nTPM]":"2.4","Tissue RNA - prostate [nTPM]":"18.5","Tissue RNA - rectum [nTPM]":"1.8","Tissue RNA - retina [nTPM]":"1.8","Tissue RNA - salivary gland [nTPM]":"16.6","Tissue RNA - seminal vesicle [nTPM]":"4.5","Tissue RNA - skeletal muscle [nTPM]":"3.7","Tissue RNA - skin 1 [nTPM]":"8.9","Tissue RNA - small intestine [nTPM]":"14.3","Tissue RNA - smooth muscle [nTPM]":"2.0","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"18.9","Tissue RNA - stomach 1 [nTPM]":"17.1","Tissue RNA - testis [nTPM]":"5.6","Tissue RNA - thalamus [nTPM]":"2.9","Tissue RNA - thymus [nTPM]":"3.4","Tissue RNA - thyroid gland [nTPM]":"17.0","Tissue RNA - tongue [nTPM]":"0.7","Tissue RNA - tonsil [nTPM]":"1.3","Tissue RNA - urinary bladder [nTPM]":"12.0","Tissue RNA - vagina [nTPM]":"13.9","Tissue RNA - white matter [nTPM]":"2.6","Cell RNA - A-431 [nTPM]":"1.8","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"1.1","Cell RNA - ASC diff [nTPM]":"12.7","Cell RNA - ASC TERT1 [nTPM]":"3.6","Cell RNA - BEWO [nTPM]":"5.3","Cell RNA - BJ [nTPM]":"10.7","Cell RNA - BJ hTERT+ [nTPM]":"8.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.7","Cell RNA - CACO-2 [nTPM]":"0.6","Cell RNA - CAPAN-2 [nTPM]":"6.4","Cell RNA - Daudi [nTPM]":"0.8","Cell RNA - EFO-21 [nTPM]":"10.7","Cell RNA - fHDF\/TERT166 [nTPM]":"5.0","Cell RNA - GAMG [nTPM]":"1.0","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"6.1","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"1.0","Cell RNA - HeLa [nTPM]":"0.8","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"5.8","Cell RNA - HL-60 [nTPM]":"0.8","Cell RNA - HMC-1 [nTPM]":"4.6","Cell RNA - HSkMC [nTPM]":"9.3","Cell RNA - hTCEpi [nTPM]":"3.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.6","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"3.4","Cell RNA - HUVEC TERT2 [nTPM]":"1.0","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.6","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"1.6","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"2.2","Cell RNA - NB-4 [nTPM]":"2.5","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"11.9","Cell RNA - PC-3 [nTPM]":"5.5","Cell RNA - REH [nTPM]":"2.7","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.1","Cell RNA - RPTEC TERT1 [nTPM]":"3.5","Cell RNA - RT4 [nTPM]":"0.9","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"3.3","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"5.7","Cell RNA - SuSa [nTPM]":"1.3","Cell RNA - T-47d [nTPM]":"1.2","Cell RNA - THP-1 [nTPM]":"2.3","Cell RNA - TIME [nTPM]":"9.3","Cell RNA - U-138 MG [nTPM]":"9.0","Cell RNA - U-2 OS [nTPM]":"1.6","Cell RNA - U-2197 [nTPM]":"2.6","Cell RNA - U-251 MG [nTPM]":"1.2","Cell RNA - U-266\/70 [nTPM]":"29.0","Cell RNA - U-266\/84 [nTPM]":"1.4","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"7.8","Cell RNA - U-937 [nTPM]":"3.3","Cell RNA - WM-115 [nTPM]":"1.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.5","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.4","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"1.8","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"1.8","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"1.7","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"3.4","Brain RNA - basal ganglia [nTPM]":"3.4","Brain RNA - cerebellum [nTPM]":"9.2","Brain RNA - cerebral cortex [nTPM]":"7.5","Brain RNA - hippocampal formation [nTPM]":"3.8","Brain RNA - hypothalamus [nTPM]":"1.5","Brain RNA - medulla oblongata [nTPM]":"3.2","Brain RNA - midbrain [nTPM]":"2.1","Brain RNA - pons [nTPM]":"2.4","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"2.9","Brain RNA - white matter [nTPM]":"2.6","Single Cell Type RNA - Adipocytes [nTPM]":"8.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.0","Single Cell Type RNA - Astrocytes [nTPM]":"4.9","Single Cell Type RNA - B-cells [nTPM]":"5.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"2.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"1.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"4.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.0","Single Cell Type RNA - Endothelial cells [nTPM]":"4.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.7","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.7","Single Cell Type RNA - Fibroblasts [nTPM]":"13.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.0","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"8.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"2.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"5.0","Single Cell Type RNA - Langerhans cells [nTPM]":"3.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"19.6","Single Cell Type RNA - Macrophages [nTPM]":"7.3","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"1.6","Single Cell Type RNA - Muller glia cells [nTPM]":"1.1","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.4","Single Cell Type RNA - Paneth cells [nTPM]":"6.9","Single Cell Type RNA - Peritubular cells [nTPM]":"10.5","Single Cell Type RNA - Plasma cells [nTPM]":"15.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.4","Single Cell Type RNA - Spermatocytes [nTPM]":"3.7","Single Cell Type RNA - Spermatogonia [nTPM]":"1.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"5.6","Single Cell Type RNA - Theca cells [nTPM]":"4.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.3","Single Cell Type RNA - Urothelial cells [nTPM]":"7.9"},{"Gene":"IFIH1","Gene synonym":["Hlcd","IDDM19","MDA-5","MDA5"],"Ensembl":"ENSG00000115267","Gene description":"Interferon induced with helicase C domain 1","Uniprot":["Q9BYX4"],"Chromosome":"2","Position":"162267074-162318684","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Antiviral defense","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":["Helicase","Hydrolase","RNA-binding"],"Disease involvement":["Aicardi-Goutieres syndrome","Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"38.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"55.6","Late spermatids":"53.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+ SV40 Large T+":"62.3","BJ hTERT+ SV40 Large T+ RasG12V":"71.5","Karpas-707":"38.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002656"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA002656":"AB_1079344"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.2","Tissue RNA - adrenal gland [nTPM]":"6.4","Tissue RNA - amygdala [nTPM]":"3.1","Tissue RNA - appendix [nTPM]":"12.7","Tissue RNA - basal ganglia [nTPM]":"4.3","Tissue RNA - bone marrow [nTPM]":"38.1","Tissue RNA - breast [nTPM]":"5.9","Tissue RNA - cerebellum [nTPM]":"3.2","Tissue RNA - cerebral cortex [nTPM]":"3.0","Tissue RNA - cervix [nTPM]":"6.5","Tissue RNA - choroid plexus [nTPM]":"4.4","Tissue RNA - colon [nTPM]":"7.4","Tissue RNA - duodenum [nTPM]":"13.1","Tissue RNA - endometrium 1 [nTPM]":"6.4","Tissue RNA - epididymis [nTPM]":"4.3","Tissue RNA - esophagus [nTPM]":"7.5","Tissue RNA - fallopian tube [nTPM]":"7.2","Tissue RNA - gallbladder [nTPM]":"9.5","Tissue RNA - heart muscle [nTPM]":"5.1","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"3.3","Tissue RNA - kidney [nTPM]":"5.6","Tissue RNA - liver [nTPM]":"8.5","Tissue RNA - lung [nTPM]":"10.9","Tissue RNA - lymph node [nTPM]":"11.7","Tissue RNA - medulla oblongata [nTPM]":"7.2","Tissue RNA - midbrain [nTPM]":"3.4","Tissue RNA - ovary [nTPM]":"7.0","Tissue RNA - pancreas [nTPM]":"7.1","Tissue RNA - parathyroid gland [nTPM]":"8.1","Tissue RNA - pituitary gland [nTPM]":"5.9","Tissue RNA - placenta [nTPM]":"8.3","Tissue RNA - pons [nTPM]":"5.0","Tissue RNA - prostate [nTPM]":"5.5","Tissue RNA - rectum [nTPM]":"6.8","Tissue RNA - retina [nTPM]":"1.1","Tissue RNA - salivary gland [nTPM]":"17.5","Tissue RNA - seminal vesicle [nTPM]":"4.7","Tissue RNA - skeletal muscle [nTPM]":"1.7","Tissue RNA - skin 1 [nTPM]":"5.0","Tissue RNA - small intestine [nTPM]":"10.0","Tissue RNA - smooth muscle [nTPM]":"5.7","Tissue RNA - spinal cord [nTPM]":"8.1","Tissue RNA - spleen [nTPM]":"16.4","Tissue RNA - stomach 1 [nTPM]":"9.6","Tissue RNA - testis [nTPM]":"2.4","Tissue RNA - thalamus [nTPM]":"4.2","Tissue RNA - thymus [nTPM]":"10.9","Tissue RNA - thyroid gland [nTPM]":"6.0","Tissue RNA - tongue [nTPM]":"3.2","Tissue RNA - tonsil [nTPM]":"9.7","Tissue RNA - urinary bladder [nTPM]":"6.4","Tissue RNA - vagina [nTPM]":"5.2","Tissue RNA - white matter [nTPM]":"4.4","Cell RNA - A-431 [nTPM]":"6.7","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"7.4","Cell RNA - ASC TERT1 [nTPM]":"6.0","Cell RNA - BEWO [nTPM]":"2.8","Cell RNA - BJ [nTPM]":"1.2","Cell RNA - BJ hTERT+ [nTPM]":"17.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"62.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"71.5","Cell RNA - CACO-2 [nTPM]":"1.2","Cell RNA - CAPAN-2 [nTPM]":"16.7","Cell RNA - Daudi [nTPM]":"13.3","Cell RNA - EFO-21 [nTPM]":"10.5","Cell RNA - fHDF\/TERT166 [nTPM]":"1.0","Cell RNA - GAMG [nTPM]":"31.9","Cell RNA - HaCaT [nTPM]":"8.5","Cell RNA - HAP1 [nTPM]":"1.1","Cell RNA - HBEC3-KT [nTPM]":"9.8","Cell RNA - HBF TERT88 [nTPM]":"6.3","Cell RNA - HDLM-2 [nTPM]":"35.4","Cell RNA - HEK 293 [nTPM]":"4.5","Cell RNA - HEL [nTPM]":"7.1","Cell RNA - HeLa [nTPM]":"0.8","Cell RNA - Hep G2 [nTPM]":"2.8","Cell RNA - HHSteC [nTPM]":"5.0","Cell RNA - HL-60 [nTPM]":"8.2","Cell RNA - HMC-1 [nTPM]":"6.4","Cell RNA - HSkMC [nTPM]":"5.3","Cell RNA - hTCEpi [nTPM]":"4.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.9","Cell RNA - hTERT-HME1 [nTPM]":"1.7","Cell RNA - hTERT-RPE1 [nTPM]":"6.5","Cell RNA - HUVEC TERT2 [nTPM]":"4.9","Cell RNA - JURKAT [nTPM]":"6.9","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"38.9","Cell RNA - LHCN-M2 [nTPM]":"1.0","Cell RNA - MCF7 [nTPM]":"12.5","Cell RNA - MOLT-4 [nTPM]":"9.3","Cell RNA - NB-4 [nTPM]":"6.4","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"5.4","Cell RNA - PC-3 [nTPM]":"3.8","Cell RNA - REH [nTPM]":"7.5","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"18.8","Cell RNA - RPTEC TERT1 [nTPM]":"5.9","Cell RNA - RT4 [nTPM]":"7.3","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"3.7","Cell RNA - SK-BR-3 [nTPM]":"20.7","Cell RNA - SK-MEL-30 [nTPM]":"34.0","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"5.7","Cell RNA - THP-1 [nTPM]":"7.1","Cell RNA - TIME [nTPM]":"4.1","Cell RNA - U-138 MG [nTPM]":"1.9","Cell RNA - U-2 OS [nTPM]":"1.7","Cell RNA - U-2197 [nTPM]":"1.1","Cell RNA - U-251 MG [nTPM]":"2.7","Cell RNA - U-266\/70 [nTPM]":"15.2","Cell RNA - U-266\/84 [nTPM]":"26.8","Cell RNA - U-698 [nTPM]":"1.9","Cell RNA - U-87 MG [nTPM]":"3.5","Cell RNA - U-937 [nTPM]":"6.5","Cell RNA - WM-115 [nTPM]":"5.6","Blood RNA - basophil [nTPM]":"4.4","Blood RNA - classical monocyte [nTPM]":"11.5","Blood RNA - eosinophil [nTPM]":"4.4","Blood RNA - gdT-cell [nTPM]":"6.6","Blood RNA - intermediate monocyte [nTPM]":"12.5","Blood RNA - MAIT T-cell [nTPM]":"9.2","Blood RNA - memory B-cell [nTPM]":"12.4","Blood RNA - memory CD4 T-cell [nTPM]":"8.2","Blood RNA - memory CD8 T-cell [nTPM]":"7.2","Blood RNA - myeloid DC [nTPM]":"11.1","Blood RNA - naive B-cell [nTPM]":"12.8","Blood RNA - naive CD4 T-cell [nTPM]":"6.7","Blood RNA - naive CD8 T-cell [nTPM]":"6.9","Blood RNA - neutrophil [nTPM]":"15.2","Blood RNA - NK-cell [nTPM]":"4.0","Blood RNA - non-classical monocyte [nTPM]":"12.7","Blood RNA - plasmacytoid DC [nTPM]":"1.6","Blood RNA - T-reg [nTPM]":"10.3","Blood RNA - total PBMC [nTPM]":"7.8","Brain RNA - amygdala [nTPM]":"3.1","Brain RNA - basal ganglia [nTPM]":"4.3","Brain RNA - cerebellum [nTPM]":"3.2","Brain RNA - cerebral cortex [nTPM]":"3.0","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"3.3","Brain RNA - medulla oblongata [nTPM]":"7.2","Brain RNA - midbrain [nTPM]":"3.4","Brain RNA - pons [nTPM]":"5.0","Brain RNA - spinal cord [nTPM]":"8.1","Brain RNA - thalamus [nTPM]":"4.2","Brain RNA - white matter [nTPM]":"4.4","Single Cell Type RNA - Adipocytes [nTPM]":"24.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.0","Single Cell Type RNA - Astrocytes [nTPM]":"4.6","Single Cell Type RNA - B-cells [nTPM]":"20.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"11.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.4","Single Cell Type RNA - dendritic cells [nTPM]":"10.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"18.7","Single Cell Type RNA - Early spermatids [nTPM]":"55.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.9","Single Cell Type RNA - Endothelial cells [nTPM]":"22.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.7","Single Cell Type RNA - Erythroid cells [nTPM]":"8.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.5","Single Cell Type RNA - Fibroblasts [nTPM]":"8.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.2","Single Cell Type RNA - granulocytes [nTPM]":"13.3","Single Cell Type RNA - Granulosa cells [nTPM]":"10.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"6.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.5","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"12.8","Single Cell Type RNA - Langerhans cells [nTPM]":"8.7","Single Cell Type RNA - Late spermatids [nTPM]":"53.3","Single Cell Type RNA - Leydig cells [nTPM]":"13.7","Single Cell Type RNA - Macrophages [nTPM]":"20.0","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"28.1","Single Cell Type RNA - monocytes [nTPM]":"23.9","Single Cell Type RNA - Muller glia cells [nTPM]":"7.3","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.4","Single Cell Type RNA - Paneth cells [nTPM]":"10.1","Single Cell Type RNA - Peritubular cells [nTPM]":"13.2","Single Cell Type RNA - Plasma cells [nTPM]":"16.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.9","Single Cell Type RNA - Spermatocytes [nTPM]":"1.6","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - T-cells [nTPM]":"13.1","Single Cell Type RNA - Theca cells [nTPM]":"6.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.7","Single Cell Type RNA - Urothelial cells [nTPM]":"11.1"},{"Gene":"IGHMBP2","Gene synonym":["CATF1","CMT2S","HCSA","HMN6","SMARD1","SMUBP2","ZFAND7"],"Ensembl":"ENSG00000132740","Gene description":"Immunoglobulin mu DNA binding protein 2","Uniprot":["P38935"],"Chromosome":"11","Position":"68903863-68940602","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Helicase","Hydrolase","Ribonucleoprotein","RNA-binding","tRNA-binding"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"94.6","Late spermatids":"46.9","Spermatocytes":"51.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004092","HPA060994"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA004092":null,"HPA060994":"AB_2684406"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.89e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.29e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.2","Tissue RNA - adrenal gland [nTPM]":"4.0","Tissue RNA - amygdala [nTPM]":"1.2","Tissue RNA - appendix [nTPM]":"2.5","Tissue RNA - basal ganglia [nTPM]":"1.3","Tissue RNA - bone marrow [nTPM]":"6.0","Tissue RNA - breast [nTPM]":"5.4","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"1.7","Tissue RNA - cervix [nTPM]":"7.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"11.8","Tissue RNA - duodenum [nTPM]":"1.5","Tissue RNA - endometrium 1 [nTPM]":"7.8","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"5.5","Tissue RNA - fallopian tube [nTPM]":"6.7","Tissue RNA - gallbladder [nTPM]":"1.7","Tissue RNA - heart muscle [nTPM]":"5.2","Tissue RNA - hippocampal formation [nTPM]":"1.6","Tissue RNA - hypothalamus [nTPM]":"1.2","Tissue RNA - kidney [nTPM]":"4.4","Tissue RNA - liver [nTPM]":"6.3","Tissue RNA - lung [nTPM]":"5.1","Tissue RNA - lymph node [nTPM]":"3.3","Tissue RNA - medulla oblongata [nTPM]":"0.8","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"6.1","Tissue RNA - pancreas [nTPM]":"5.2","Tissue RNA - parathyroid gland [nTPM]":"2.8","Tissue RNA - pituitary gland [nTPM]":"4.0","Tissue RNA - placenta [nTPM]":"2.0","Tissue RNA - pons [nTPM]":"0.7","Tissue RNA - prostate [nTPM]":"6.3","Tissue RNA - rectum [nTPM]":"1.5","Tissue RNA - retina [nTPM]":"1.4","Tissue RNA - salivary gland [nTPM]":"6.4","Tissue RNA - seminal vesicle [nTPM]":"3.1","Tissue RNA - skeletal muscle [nTPM]":"8.5","Tissue RNA - skin 1 [nTPM]":"7.7","Tissue RNA - small intestine [nTPM]":"6.3","Tissue RNA - smooth muscle [nTPM]":"2.6","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"5.7","Tissue RNA - stomach 1 [nTPM]":"6.2","Tissue RNA - testis [nTPM]":"15.4","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"4.3","Tissue RNA - thyroid gland [nTPM]":"4.9","Tissue RNA - tongue [nTPM]":"3.8","Tissue RNA - tonsil [nTPM]":"1.7","Tissue RNA - urinary bladder [nTPM]":"6.3","Tissue RNA - vagina [nTPM]":"5.8","Tissue RNA - white matter [nTPM]":"1.1","Cell RNA - A-431 [nTPM]":"5.1","Cell RNA - A549 [nTPM]":"7.3","Cell RNA - AF22 [nTPM]":"4.0","Cell RNA - AN3-CA [nTPM]":"7.4","Cell RNA - ASC diff [nTPM]":"3.6","Cell RNA - ASC TERT1 [nTPM]":"3.1","Cell RNA - BEWO [nTPM]":"5.2","Cell RNA - BJ [nTPM]":"5.8","Cell RNA - BJ hTERT+ [nTPM]":"3.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.6","Cell RNA - CACO-2 [nTPM]":"14.5","Cell RNA - CAPAN-2 [nTPM]":"7.0","Cell RNA - Daudi [nTPM]":"7.3","Cell RNA - EFO-21 [nTPM]":"9.7","Cell RNA - fHDF\/TERT166 [nTPM]":"3.3","Cell RNA - GAMG [nTPM]":"6.9","Cell RNA - HaCaT [nTPM]":"8.0","Cell RNA - HAP1 [nTPM]":"5.8","Cell RNA - HBEC3-KT [nTPM]":"4.9","Cell RNA - HBF TERT88 [nTPM]":"1.8","Cell RNA - HDLM-2 [nTPM]":"8.3","Cell RNA - HEK 293 [nTPM]":"6.2","Cell RNA - HEL [nTPM]":"6.6","Cell RNA - HeLa [nTPM]":"9.6","Cell RNA - Hep G2 [nTPM]":"5.6","Cell RNA - HHSteC [nTPM]":"5.5","Cell RNA - HL-60 [nTPM]":"6.5","Cell RNA - HMC-1 [nTPM]":"7.4","Cell RNA - HSkMC [nTPM]":"1.8","Cell RNA - hTCEpi [nTPM]":"4.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.2","Cell RNA - hTERT-HME1 [nTPM]":"4.6","Cell RNA - hTERT-RPE1 [nTPM]":"4.5","Cell RNA - HUVEC TERT2 [nTPM]":"4.6","Cell RNA - JURKAT [nTPM]":"11.1","Cell RNA - K-562 [nTPM]":"10.6","Cell RNA - Karpas-707 [nTPM]":"4.6","Cell RNA - LHCN-M2 [nTPM]":"2.3","Cell RNA - MCF7 [nTPM]":"5.1","Cell RNA - MOLT-4 [nTPM]":"11.1","Cell RNA - NB-4 [nTPM]":"8.9","Cell RNA - NTERA-2 [nTPM]":"2.3","Cell RNA - OE19 [nTPM]":"7.9","Cell RNA - PC-3 [nTPM]":"10.3","Cell RNA - REH [nTPM]":"9.4","Cell RNA - RH-30 [nTPM]":"5.7","Cell RNA - RPMI-8226 [nTPM]":"7.6","Cell RNA - RPTEC TERT1 [nTPM]":"3.3","Cell RNA - RT4 [nTPM]":"5.9","Cell RNA - SCLC-21H [nTPM]":"8.6","Cell RNA - SH-SY5Y [nTPM]":"5.4","Cell RNA - SiHa [nTPM]":"7.4","Cell RNA - SK-BR-3 [nTPM]":"6.1","Cell RNA - SK-MEL-30 [nTPM]":"16.6","Cell RNA - SuSa [nTPM]":"3.0","Cell RNA - T-47d [nTPM]":"9.3","Cell RNA - THP-1 [nTPM]":"6.0","Cell RNA - TIME [nTPM]":"6.6","Cell RNA - U-138 MG [nTPM]":"5.3","Cell RNA - U-2 OS [nTPM]":"3.8","Cell RNA - U-2197 [nTPM]":"7.7","Cell RNA - U-251 MG [nTPM]":"6.6","Cell RNA - U-266\/70 [nTPM]":"6.0","Cell RNA - U-266\/84 [nTPM]":"6.3","Cell RNA - U-698 [nTPM]":"6.9","Cell RNA - U-87 MG [nTPM]":"5.3","Cell RNA - U-937 [nTPM]":"6.1","Cell RNA - WM-115 [nTPM]":"5.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.0","Blood RNA - eosinophil [nTPM]":"0.8","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"1.8","Blood RNA - MAIT T-cell [nTPM]":"1.3","Blood RNA - memory B-cell [nTPM]":"1.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.0","Blood RNA - myeloid DC [nTPM]":"1.8","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"1.1","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"1.3","Brain RNA - amygdala [nTPM]":"1.2","Brain RNA - basal ganglia [nTPM]":"1.3","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"1.7","Brain RNA - hippocampal formation [nTPM]":"1.6","Brain RNA - hypothalamus [nTPM]":"1.2","Brain RNA - medulla oblongata [nTPM]":"0.8","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.7","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"1.1","Single Cell Type RNA - Adipocytes [nTPM]":"6.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.7","Single Cell Type RNA - Astrocytes [nTPM]":"7.5","Single Cell Type RNA - B-cells [nTPM]":"5.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"9.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"6.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.9","Single Cell Type RNA - dendritic cells [nTPM]":"10.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.1","Single Cell Type RNA - Early spermatids [nTPM]":"94.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.1","Single Cell Type RNA - Endothelial cells [nTPM]":"6.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"9.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.4","Single Cell Type RNA - Fibroblasts [nTPM]":"5.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.0","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"10.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"6.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.8","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.1","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.5","Single Cell Type RNA - Langerhans cells [nTPM]":"4.3","Single Cell Type RNA - Late spermatids [nTPM]":"46.9","Single Cell Type RNA - Leydig cells [nTPM]":"7.8","Single Cell Type RNA - Macrophages [nTPM]":"7.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"7.3","Single Cell Type RNA - Muller glia cells [nTPM]":"6.6","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.5","Single Cell Type RNA - Paneth cells [nTPM]":"8.4","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"5.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.1","Single Cell Type RNA - Spermatocytes [nTPM]":"51.6","Single Cell Type RNA - Spermatogonia [nTPM]":"7.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.7","Single Cell Type RNA - T-cells [nTPM]":"8.0","Single Cell Type RNA - Theca cells [nTPM]":"4.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.1","Single Cell Type RNA - Urothelial cells [nTPM]":"6.3"},{"Gene":"IL1RAPL1","Gene synonym":["IL1R8","IL1RAPL","MRX10","MRX21","MRX34","OPHN4","TIGIRR-2"],"Ensembl":"ENSG00000169306","Gene description":"Interleukin 1 receptor accessory protein like 1","Uniprot":["Q9NZN1"],"Chromosome":"X","Position":"28587446-29956718","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Receptor"],"Disease involvement":["Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"73","RNA tissue specific nTPM":{"brain":"33.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"1315.7","Inhibitory neurons":"2598.6","Oligodendrocyte precursor cells":"1954.3","Oligodendrocytes":"6420.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"white matter":"33.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"GAMG":"8.7","WM-115":"2.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"3.9","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"12.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"1.9","Tissue RNA - cerebral cortex [nTPM]":"8.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"3.3","Tissue RNA - hypothalamus [nTPM]":"4.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"7.8","Tissue RNA - midbrain [nTPM]":"4.5","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"5.7","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"3.9","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"8.5","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"33.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"8.7","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"1.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.4","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.7","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.6","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"2.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.9","Brain RNA - basal ganglia [nTPM]":"12.1","Brain RNA - cerebellum [nTPM]":"1.9","Brain RNA - cerebral cortex [nTPM]":"8.1","Brain RNA - hippocampal formation [nTPM]":"3.3","Brain RNA - hypothalamus [nTPM]":"4.0","Brain RNA - medulla oblongata [nTPM]":"7.8","Brain RNA - midbrain [nTPM]":"4.5","Brain RNA - pons [nTPM]":"5.7","Brain RNA - spinal cord [nTPM]":"3.9","Brain RNA - thalamus [nTPM]":"8.5","Brain RNA - white matter [nTPM]":"33.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"64.6","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"2.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1315.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"26.1","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2598.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.9","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"42.2","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1954.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6420.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"1.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"IMMP2L","Gene synonym":["IMMP2L-IT1","IMP2"],"Ensembl":"ENSG00000184903","Gene description":"Inner mitochondrial membrane peptidase subunit 2","Uniprot":["Q96T52"],"Chromosome":"7","Position":"110662644-111562517","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"247.8","Distal tubular cells":"160.4","Excitatory neurons":"365.4","Inhibitory neurons":"373.9","Microglial cells":"455.3","Oligodendrocyte precursor cells":"273.9","Oligodendrocytes":"233.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026711"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA026711":"AB_1851760"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.89e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Tissue RNA - adipose tissue [nTPM]":"19.2","Tissue RNA - adrenal gland [nTPM]":"14.2","Tissue RNA - amygdala [nTPM]":"10.4","Tissue RNA - appendix [nTPM]":"5.1","Tissue RNA - basal ganglia [nTPM]":"12.5","Tissue RNA - bone marrow [nTPM]":"5.2","Tissue RNA - breast [nTPM]":"15.7","Tissue RNA - cerebellum [nTPM]":"9.6","Tissue RNA - cerebral cortex [nTPM]":"11.7","Tissue RNA - cervix [nTPM]":"12.4","Tissue RNA - choroid plexus [nTPM]":"14.2","Tissue RNA - colon [nTPM]":"14.6","Tissue RNA - duodenum [nTPM]":"7.6","Tissue RNA - endometrium 1 [nTPM]":"15.3","Tissue RNA - epididymis [nTPM]":"11.9","Tissue RNA - esophagus [nTPM]":"8.0","Tissue RNA - fallopian tube [nTPM]":"16.0","Tissue RNA - gallbladder [nTPM]":"8.5","Tissue RNA - heart muscle [nTPM]":"13.1","Tissue RNA - hippocampal formation [nTPM]":"11.9","Tissue RNA - hypothalamus [nTPM]":"12.2","Tissue RNA - kidney [nTPM]":"34.0","Tissue RNA - liver [nTPM]":"25.7","Tissue RNA - lung [nTPM]":"8.1","Tissue RNA - lymph node [nTPM]":"7.5","Tissue RNA - medulla oblongata [nTPM]":"11.3","Tissue RNA - midbrain [nTPM]":"11.3","Tissue RNA - ovary [nTPM]":"19.5","Tissue RNA - pancreas [nTPM]":"12.1","Tissue RNA - parathyroid gland [nTPM]":"20.1","Tissue RNA - pituitary gland [nTPM]":"8.0","Tissue RNA - placenta [nTPM]":"9.0","Tissue RNA - pons [nTPM]":"11.3","Tissue RNA - prostate [nTPM]":"19.0","Tissue RNA - rectum [nTPM]":"8.2","Tissue RNA - retina [nTPM]":"9.2","Tissue RNA - salivary gland [nTPM]":"11.1","Tissue RNA - seminal vesicle [nTPM]":"21.1","Tissue RNA - skeletal muscle [nTPM]":"27.3","Tissue RNA - skin 1 [nTPM]":"10.2","Tissue RNA - small intestine [nTPM]":"12.9","Tissue RNA - smooth muscle [nTPM]":"14.2","Tissue RNA - spinal cord [nTPM]":"10.9","Tissue RNA - spleen [nTPM]":"8.4","Tissue RNA - stomach 1 [nTPM]":"11.8","Tissue RNA - testis [nTPM]":"9.9","Tissue RNA - thalamus [nTPM]":"11.4","Tissue RNA - thymus [nTPM]":"8.9","Tissue RNA - thyroid gland [nTPM]":"23.5","Tissue RNA - tongue [nTPM]":"25.1","Tissue RNA - tonsil [nTPM]":"7.5","Tissue RNA - urinary bladder [nTPM]":"12.5","Tissue RNA - vagina [nTPM]":"10.5","Tissue RNA - white matter [nTPM]":"13.1","Cell RNA - A-431 [nTPM]":"17.5","Cell RNA - A549 [nTPM]":"10.3","Cell RNA - AF22 [nTPM]":"6.1","Cell RNA - AN3-CA [nTPM]":"25.1","Cell RNA - ASC diff [nTPM]":"15.8","Cell RNA - ASC TERT1 [nTPM]":"16.0","Cell RNA - BEWO [nTPM]":"10.7","Cell RNA - BJ [nTPM]":"11.8","Cell RNA - BJ hTERT+ [nTPM]":"11.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.1","Cell RNA - CACO-2 [nTPM]":"5.1","Cell RNA - CAPAN-2 [nTPM]":"19.8","Cell RNA - Daudi [nTPM]":"28.4","Cell RNA - EFO-21 [nTPM]":"31.4","Cell RNA - fHDF\/TERT166 [nTPM]":"10.2","Cell RNA - GAMG [nTPM]":"14.3","Cell RNA - HaCaT [nTPM]":"9.6","Cell RNA - HAP1 [nTPM]":"6.6","Cell RNA - HBEC3-KT [nTPM]":"23.6","Cell RNA - HBF TERT88 [nTPM]":"12.7","Cell RNA - HDLM-2 [nTPM]":"17.9","Cell RNA - HEK 293 [nTPM]":"6.7","Cell RNA - HEL [nTPM]":"9.7","Cell RNA - HeLa [nTPM]":"44.2","Cell RNA - Hep G2 [nTPM]":"14.0","Cell RNA - HHSteC [nTPM]":"24.2","Cell RNA - HL-60 [nTPM]":"18.2","Cell RNA - HMC-1 [nTPM]":"1.1","Cell RNA - HSkMC [nTPM]":"27.9","Cell RNA - hTCEpi [nTPM]":"30.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.3","Cell RNA - hTERT-HME1 [nTPM]":"21.4","Cell RNA - hTERT-RPE1 [nTPM]":"35.0","Cell RNA - HUVEC TERT2 [nTPM]":"10.2","Cell RNA - JURKAT [nTPM]":"26.2","Cell RNA - K-562 [nTPM]":"32.0","Cell RNA - Karpas-707 [nTPM]":"21.4","Cell RNA - LHCN-M2 [nTPM]":"5.9","Cell RNA - MCF7 [nTPM]":"12.3","Cell RNA - MOLT-4 [nTPM]":"24.4","Cell RNA - NB-4 [nTPM]":"20.3","Cell RNA - NTERA-2 [nTPM]":"6.0","Cell RNA - OE19 [nTPM]":"33.2","Cell RNA - PC-3 [nTPM]":"15.8","Cell RNA - REH [nTPM]":"5.1","Cell RNA - RH-30 [nTPM]":"50.0","Cell RNA - RPMI-8226 [nTPM]":"15.0","Cell RNA - RPTEC TERT1 [nTPM]":"28.0","Cell RNA - RT4 [nTPM]":"7.3","Cell RNA - SCLC-21H [nTPM]":"7.0","Cell RNA - SH-SY5Y [nTPM]":"22.1","Cell RNA - SiHa [nTPM]":"5.1","Cell RNA - SK-BR-3 [nTPM]":"23.8","Cell RNA - SK-MEL-30 [nTPM]":"67.3","Cell RNA - SuSa [nTPM]":"17.2","Cell RNA - T-47d [nTPM]":"9.6","Cell RNA - THP-1 [nTPM]":"10.4","Cell RNA - TIME [nTPM]":"6.5","Cell RNA - U-138 MG [nTPM]":"11.8","Cell RNA - U-2 OS [nTPM]":"12.3","Cell RNA - U-2197 [nTPM]":"11.9","Cell RNA - U-251 MG [nTPM]":"14.4","Cell RNA - U-266\/70 [nTPM]":"12.2","Cell RNA - U-266\/84 [nTPM]":"3.5","Cell RNA - U-698 [nTPM]":"17.4","Cell RNA - U-87 MG [nTPM]":"12.9","Cell RNA - U-937 [nTPM]":"8.4","Cell RNA - WM-115 [nTPM]":"63.1","Blood RNA - basophil [nTPM]":"15.9","Blood RNA - classical monocyte [nTPM]":"9.1","Blood RNA - eosinophil [nTPM]":"2.9","Blood RNA - gdT-cell [nTPM]":"10.5","Blood RNA - intermediate monocyte [nTPM]":"11.9","Blood RNA - MAIT T-cell [nTPM]":"19.4","Blood RNA - memory B-cell [nTPM]":"28.5","Blood RNA - memory CD4 T-cell [nTPM]":"18.3","Blood RNA - memory CD8 T-cell [nTPM]":"12.3","Blood RNA - myeloid DC [nTPM]":"17.0","Blood RNA - naive B-cell [nTPM]":"38.7","Blood RNA - naive CD4 T-cell [nTPM]":"25.0","Blood RNA - naive CD8 T-cell [nTPM]":"17.6","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"47.0","Blood RNA - non-classical monocyte [nTPM]":"17.3","Blood RNA - plasmacytoid DC [nTPM]":"21.3","Blood RNA - T-reg [nTPM]":"12.4","Blood RNA - total PBMC [nTPM]":"8.1","Brain RNA - amygdala [nTPM]":"10.4","Brain RNA - basal ganglia [nTPM]":"12.5","Brain RNA - cerebellum [nTPM]":"9.6","Brain RNA - cerebral cortex [nTPM]":"11.7","Brain RNA - hippocampal formation [nTPM]":"11.9","Brain RNA - hypothalamus [nTPM]":"12.2","Brain RNA - medulla oblongata [nTPM]":"11.3","Brain RNA - midbrain [nTPM]":"11.3","Brain RNA - pons [nTPM]":"11.3","Brain RNA - spinal cord [nTPM]":"10.9","Brain RNA - thalamus [nTPM]":"11.4","Brain RNA - white matter [nTPM]":"13.1","Single Cell Type RNA - Adipocytes [nTPM]":"22.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.2","Single Cell Type RNA - Astrocytes [nTPM]":"247.8","Single Cell Type RNA - B-cells [nTPM]":"20.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"32.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"34.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"41.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"39.9","Single Cell Type RNA - Bipolar cells [nTPM]":"11.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"35.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"39.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"23.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"47.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"22.4","Single Cell Type RNA - dendritic cells [nTPM]":"11.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"160.4","Single Cell Type RNA - Ductal cells [nTPM]":"30.1","Single Cell Type RNA - Early spermatids [nTPM]":"8.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.6","Single Cell Type RNA - Endothelial cells [nTPM]":"15.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.3","Single Cell Type RNA - Erythroid cells [nTPM]":"21.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"365.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"27.1","Single Cell Type RNA - Fibroblasts [nTPM]":"19.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.0","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"11.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"23.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.7","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"373.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.0","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"4.9","Single Cell Type RNA - Langerhans cells [nTPM]":"14.1","Single Cell Type RNA - Late spermatids [nTPM]":"5.6","Single Cell Type RNA - Leydig cells [nTPM]":"49.4","Single Cell Type RNA - Macrophages [nTPM]":"6.1","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"455.3","Single Cell Type RNA - monocytes [nTPM]":"10.1","Single Cell Type RNA - Muller glia cells [nTPM]":"16.3","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"273.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"233.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.8","Single Cell Type RNA - Paneth cells [nTPM]":"6.8","Single Cell Type RNA - Peritubular cells [nTPM]":"35.0","Single Cell Type RNA - Plasma cells [nTPM]":"9.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"36.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"25.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"66.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"46.7","Single Cell Type RNA - Spermatocytes [nTPM]":"24.2","Single Cell Type RNA - Spermatogonia [nTPM]":"12.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"26.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.3","Single Cell Type RNA - T-cells [nTPM]":"12.6","Single Cell Type RNA - Theca cells [nTPM]":"18.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.7","Single Cell Type RNA - Urothelial cells [nTPM]":"22.1"},{"Gene":"IMPA1","Gene synonym":["IMPA"],"Ensembl":"ENSG00000133731","Gene description":"Inositol monophosphatase 1","Uniprot":["P29218"],"Chromosome":"8","Position":"81656914-81686331","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037489"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"310000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA037489":"AB_10671757"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-3"},"Tissue RNA - adipose tissue [nTPM]":"12.8","Tissue RNA - adrenal gland [nTPM]":"11.3","Tissue RNA - amygdala [nTPM]":"12.7","Tissue RNA - appendix [nTPM]":"12.7","Tissue RNA - basal ganglia [nTPM]":"13.3","Tissue RNA - bone marrow [nTPM]":"27.0","Tissue RNA - breast [nTPM]":"10.2","Tissue RNA - cerebellum [nTPM]":"11.8","Tissue RNA - cerebral cortex [nTPM]":"15.8","Tissue RNA - cervix [nTPM]":"8.9","Tissue RNA - choroid plexus [nTPM]":"14.8","Tissue RNA - colon [nTPM]":"26.9","Tissue RNA - duodenum [nTPM]":"23.5","Tissue RNA - endometrium 1 [nTPM]":"10.4","Tissue RNA - epididymis [nTPM]":"11.7","Tissue RNA - esophagus [nTPM]":"20.7","Tissue RNA - fallopian tube [nTPM]":"11.8","Tissue RNA - gallbladder [nTPM]":"11.8","Tissue RNA - heart muscle [nTPM]":"25.8","Tissue RNA - hippocampal formation [nTPM]":"14.6","Tissue RNA - hypothalamus [nTPM]":"12.6","Tissue RNA - kidney [nTPM]":"16.4","Tissue RNA - liver [nTPM]":"31.3","Tissue RNA - lung [nTPM]":"10.2","Tissue RNA - lymph node [nTPM]":"17.6","Tissue RNA - medulla oblongata [nTPM]":"10.9","Tissue RNA - midbrain [nTPM]":"13.4","Tissue RNA - ovary [nTPM]":"13.5","Tissue RNA - pancreas [nTPM]":"8.6","Tissue RNA - parathyroid gland [nTPM]":"15.5","Tissue RNA - pituitary gland [nTPM]":"10.1","Tissue RNA - placenta [nTPM]":"8.2","Tissue RNA - pons [nTPM]":"13.0","Tissue RNA - prostate [nTPM]":"11.0","Tissue RNA - rectum [nTPM]":"28.4","Tissue RNA - retina [nTPM]":"18.2","Tissue RNA - salivary gland [nTPM]":"8.3","Tissue RNA - seminal vesicle [nTPM]":"8.1","Tissue RNA - skeletal muscle [nTPM]":"14.1","Tissue RNA - skin 1 [nTPM]":"5.1","Tissue RNA - small intestine [nTPM]":"23.2","Tissue RNA - smooth muscle [nTPM]":"18.0","Tissue RNA - spinal cord [nTPM]":"12.4","Tissue RNA - spleen [nTPM]":"11.2","Tissue RNA - stomach 1 [nTPM]":"14.7","Tissue RNA - testis [nTPM]":"38.2","Tissue RNA - thalamus [nTPM]":"12.1","Tissue RNA - thymus [nTPM]":"19.6","Tissue RNA - thyroid gland [nTPM]":"21.8","Tissue RNA - tongue [nTPM]":"29.0","Tissue RNA - tonsil [nTPM]":"16.3","Tissue RNA - urinary bladder [nTPM]":"14.0","Tissue RNA - vagina [nTPM]":"10.5","Tissue RNA - white matter [nTPM]":"15.1","Cell RNA - A-431 [nTPM]":"12.5","Cell RNA - A549 [nTPM]":"34.6","Cell RNA - AF22 [nTPM]":"23.3","Cell RNA - AN3-CA [nTPM]":"17.2","Cell RNA - ASC diff [nTPM]":"14.0","Cell RNA - ASC TERT1 [nTPM]":"21.9","Cell RNA - BEWO [nTPM]":"9.8","Cell RNA - BJ [nTPM]":"35.7","Cell RNA - BJ hTERT+ [nTPM]":"26.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"31.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"36.7","Cell RNA - CACO-2 [nTPM]":"16.3","Cell RNA - CAPAN-2 [nTPM]":"20.1","Cell RNA - Daudi [nTPM]":"47.2","Cell RNA - EFO-21 [nTPM]":"27.5","Cell RNA - fHDF\/TERT166 [nTPM]":"26.2","Cell RNA - GAMG [nTPM]":"45.6","Cell RNA - HaCaT [nTPM]":"9.4","Cell RNA - HAP1 [nTPM]":"27.1","Cell RNA - HBEC3-KT [nTPM]":"12.0","Cell RNA - HBF TERT88 [nTPM]":"41.3","Cell RNA - HDLM-2 [nTPM]":"50.7","Cell RNA - HEK 293 [nTPM]":"26.5","Cell RNA - HEL [nTPM]":"35.7","Cell RNA - HeLa [nTPM]":"19.2","Cell RNA - Hep G2 [nTPM]":"20.8","Cell RNA - HHSteC [nTPM]":"23.8","Cell RNA - HL-60 [nTPM]":"36.7","Cell RNA - HMC-1 [nTPM]":"35.0","Cell RNA - HSkMC [nTPM]":"20.3","Cell RNA - hTCEpi [nTPM]":"17.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"24.9","Cell RNA - hTERT-HME1 [nTPM]":"48.2","Cell RNA - hTERT-RPE1 [nTPM]":"30.2","Cell RNA - HUVEC TERT2 [nTPM]":"35.2","Cell RNA - JURKAT [nTPM]":"35.6","Cell RNA - K-562 [nTPM]":"32.8","Cell RNA - Karpas-707 [nTPM]":"38.7","Cell RNA - LHCN-M2 [nTPM]":"30.6","Cell RNA - MCF7 [nTPM]":"8.7","Cell RNA - MOLT-4 [nTPM]":"46.1","Cell RNA - NB-4 [nTPM]":"18.4","Cell RNA - NTERA-2 [nTPM]":"10.1","Cell RNA - OE19 [nTPM]":"32.2","Cell RNA - PC-3 [nTPM]":"37.2","Cell RNA - REH [nTPM]":"21.2","Cell RNA - RH-30 [nTPM]":"16.9","Cell RNA - RPMI-8226 [nTPM]":"19.2","Cell RNA - RPTEC TERT1 [nTPM]":"31.7","Cell RNA - RT4 [nTPM]":"43.5","Cell RNA - SCLC-21H [nTPM]":"9.3","Cell RNA - SH-SY5Y [nTPM]":"38.7","Cell RNA - SiHa [nTPM]":"23.9","Cell RNA - SK-BR-3 [nTPM]":"6.2","Cell RNA - SK-MEL-30 [nTPM]":"41.3","Cell RNA - SuSa [nTPM]":"39.6","Cell RNA - T-47d [nTPM]":"20.4","Cell RNA - THP-1 [nTPM]":"27.4","Cell RNA - TIME [nTPM]":"26.4","Cell RNA - U-138 MG [nTPM]":"24.9","Cell RNA - U-2 OS [nTPM]":"32.8","Cell RNA - U-2197 [nTPM]":"19.8","Cell RNA - U-251 MG [nTPM]":"44.1","Cell RNA - U-266\/70 [nTPM]":"45.2","Cell RNA - U-266\/84 [nTPM]":"58.5","Cell RNA - U-698 [nTPM]":"67.4","Cell RNA - U-87 MG [nTPM]":"29.4","Cell RNA - U-937 [nTPM]":"20.7","Cell RNA - WM-115 [nTPM]":"35.9","Blood RNA - basophil [nTPM]":"50.5","Blood RNA - classical monocyte [nTPM]":"6.6","Blood RNA - eosinophil [nTPM]":"29.4","Blood RNA - gdT-cell [nTPM]":"13.6","Blood RNA - intermediate monocyte [nTPM]":"10.3","Blood RNA - MAIT T-cell [nTPM]":"16.8","Blood RNA - memory B-cell [nTPM]":"20.3","Blood RNA - memory CD4 T-cell [nTPM]":"13.5","Blood RNA - memory CD8 T-cell [nTPM]":"14.9","Blood RNA - myeloid DC [nTPM]":"7.5","Blood RNA - naive B-cell [nTPM]":"13.7","Blood RNA - naive CD4 T-cell [nTPM]":"14.0","Blood RNA - naive CD8 T-cell [nTPM]":"16.8","Blood RNA - neutrophil [nTPM]":"11.2","Blood RNA - NK-cell [nTPM]":"20.5","Blood RNA - non-classical monocyte [nTPM]":"11.8","Blood RNA - plasmacytoid DC [nTPM]":"12.0","Blood RNA - T-reg [nTPM]":"19.6","Blood RNA - total PBMC [nTPM]":"9.5","Brain RNA - amygdala [nTPM]":"12.7","Brain RNA - basal ganglia [nTPM]":"13.3","Brain RNA - cerebellum [nTPM]":"11.8","Brain RNA - cerebral cortex [nTPM]":"15.8","Brain RNA - hippocampal formation [nTPM]":"14.6","Brain RNA - hypothalamus [nTPM]":"12.6","Brain RNA - medulla oblongata [nTPM]":"10.9","Brain RNA - midbrain [nTPM]":"13.4","Brain RNA - pons [nTPM]":"13.0","Brain RNA - spinal cord [nTPM]":"12.4","Brain RNA - thalamus [nTPM]":"12.1","Brain RNA - white matter [nTPM]":"15.1","Single Cell Type RNA - Adipocytes [nTPM]":"22.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.7","Single Cell Type RNA - Astrocytes [nTPM]":"15.3","Single Cell Type RNA - B-cells [nTPM]":"25.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"28.5","Single Cell Type RNA - Bipolar cells [nTPM]":"15.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"38.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"17.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.7","Single Cell Type RNA - dendritic cells [nTPM]":"29.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"54.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"31.3","Single Cell Type RNA - Ductal cells [nTPM]":"16.2","Single Cell Type RNA - Early spermatids [nTPM]":"4.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.7","Single Cell Type RNA - Endothelial cells [nTPM]":"16.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.5","Single Cell Type RNA - Erythroid cells [nTPM]":"11.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"20.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.0","Single Cell Type RNA - Fibroblasts [nTPM]":"16.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.3","Single Cell Type RNA - granulocytes [nTPM]":"33.0","Single Cell Type RNA - Granulosa cells [nTPM]":"11.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.9","Single Cell Type RNA - Hepatocytes [nTPM]":"32.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.3","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.8","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"16.2","Single Cell Type RNA - Langerhans cells [nTPM]":"13.1","Single Cell Type RNA - Late spermatids [nTPM]":"8.2","Single Cell Type RNA - Leydig cells [nTPM]":"15.5","Single Cell Type RNA - Macrophages [nTPM]":"16.4","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"21.9","Single Cell Type RNA - Muller glia cells [nTPM]":"23.4","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.0","Single Cell Type RNA - Paneth cells [nTPM]":"62.3","Single Cell Type RNA - Peritubular cells [nTPM]":"15.1","Single Cell Type RNA - Plasma cells [nTPM]":"18.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"30.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"30.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"25.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.9","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.0","Single Cell Type RNA - Spermatocytes [nTPM]":"78.4","Single Cell Type RNA - Spermatogonia [nTPM]":"19.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.0","Single Cell Type RNA - T-cells [nTPM]":"26.2","Single Cell Type RNA - Theca cells [nTPM]":"18.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"22.3","Single Cell Type RNA - Urothelial cells [nTPM]":"21.3"},{"Gene":"INPP5E","Gene synonym":["CORS1","JBTS1","pharbin","PPI5PIV"],"Ensembl":"ENSG00000148384","Gene description":"Inositol polyphosphate-5-phosphatase E","Uniprot":["Q9NRR6"],"Chromosome":"9","Position":"136428619-136439845","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Ciliopathy","Disease variant","Joubert syndrome","Mental retardation","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065758"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Focal adhesion sites"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Golgi apparatus","Focal adhesion sites"],"Subcellular additional location":null,"Antibody RRID":{"HPA065758":"AB_2685554"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.60e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.82e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Tissue RNA - adipose tissue [nTPM]":"12.1","Tissue RNA - adrenal gland [nTPM]":"10.8","Tissue RNA - amygdala [nTPM]":"15.0","Tissue RNA - appendix [nTPM]":"6.9","Tissue RNA - basal ganglia [nTPM]":"15.0","Tissue RNA - bone marrow [nTPM]":"6.4","Tissue RNA - breast [nTPM]":"11.7","Tissue RNA - cerebellum [nTPM]":"15.3","Tissue RNA - cerebral cortex [nTPM]":"19.9","Tissue RNA - cervix [nTPM]":"15.1","Tissue RNA - choroid plexus [nTPM]":"11.3","Tissue RNA - colon [nTPM]":"13.1","Tissue RNA - duodenum [nTPM]":"5.7","Tissue RNA - endometrium 1 [nTPM]":"15.2","Tissue RNA - epididymis [nTPM]":"2.3","Tissue RNA - esophagus [nTPM]":"10.6","Tissue RNA - fallopian tube [nTPM]":"17.6","Tissue RNA - gallbladder [nTPM]":"5.3","Tissue RNA - heart muscle [nTPM]":"13.7","Tissue RNA - hippocampal formation [nTPM]":"14.0","Tissue RNA - hypothalamus [nTPM]":"14.3","Tissue RNA - kidney [nTPM]":"13.3","Tissue RNA - liver [nTPM]":"12.2","Tissue RNA - lung [nTPM]":"11.9","Tissue RNA - lymph node [nTPM]":"8.2","Tissue RNA - medulla oblongata [nTPM]":"15.1","Tissue RNA - midbrain [nTPM]":"13.3","Tissue RNA - ovary [nTPM]":"16.2","Tissue RNA - pancreas [nTPM]":"10.8","Tissue RNA - parathyroid gland [nTPM]":"6.6","Tissue RNA - pituitary gland [nTPM]":"14.3","Tissue RNA - placenta [nTPM]":"5.7","Tissue RNA - pons [nTPM]":"15.5","Tissue RNA - prostate [nTPM]":"12.3","Tissue RNA - rectum [nTPM]":"3.3","Tissue RNA - retina [nTPM]":"7.4","Tissue RNA - salivary gland [nTPM]":"9.5","Tissue RNA - seminal vesicle [nTPM]":"5.3","Tissue RNA - skeletal muscle [nTPM]":"8.5","Tissue RNA - skin 1 [nTPM]":"11.2","Tissue RNA - small intestine [nTPM]":"11.7","Tissue RNA - smooth muscle [nTPM]":"5.6","Tissue RNA - spinal cord [nTPM]":"11.4","Tissue RNA - spleen [nTPM]":"20.8","Tissue RNA - stomach 1 [nTPM]":"8.9","Tissue RNA - testis [nTPM]":"20.1","Tissue RNA - thalamus [nTPM]":"14.8","Tissue RNA - thymus [nTPM]":"6.4","Tissue RNA - thyroid gland [nTPM]":"15.1","Tissue RNA - tongue [nTPM]":"3.8","Tissue RNA - tonsil [nTPM]":"4.7","Tissue RNA - urinary bladder [nTPM]":"12.2","Tissue RNA - vagina [nTPM]":"12.0","Tissue RNA - white matter [nTPM]":"13.9","Cell RNA - A-431 [nTPM]":"8.9","Cell RNA - A549 [nTPM]":"10.3","Cell RNA - AF22 [nTPM]":"12.6","Cell RNA - AN3-CA [nTPM]":"13.2","Cell RNA - ASC diff [nTPM]":"6.5","Cell RNA - ASC TERT1 [nTPM]":"7.1","Cell RNA - BEWO [nTPM]":"14.9","Cell RNA - BJ [nTPM]":"10.7","Cell RNA - BJ hTERT+ [nTPM]":"5.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.1","Cell RNA - CACO-2 [nTPM]":"12.5","Cell RNA - CAPAN-2 [nTPM]":"6.0","Cell RNA - Daudi [nTPM]":"10.8","Cell RNA - EFO-21 [nTPM]":"10.5","Cell RNA - fHDF\/TERT166 [nTPM]":"11.1","Cell RNA - GAMG [nTPM]":"11.9","Cell RNA - HaCaT [nTPM]":"25.2","Cell RNA - HAP1 [nTPM]":"6.2","Cell RNA - HBEC3-KT [nTPM]":"8.6","Cell RNA - HBF TERT88 [nTPM]":"2.8","Cell RNA - HDLM-2 [nTPM]":"36.8","Cell RNA - HEK 293 [nTPM]":"25.4","Cell RNA - HEL [nTPM]":"8.5","Cell RNA - HeLa [nTPM]":"27.1","Cell RNA - Hep G2 [nTPM]":"8.4","Cell RNA - HHSteC [nTPM]":"10.3","Cell RNA - HL-60 [nTPM]":"9.5","Cell RNA - HMC-1 [nTPM]":"11.9","Cell RNA - HSkMC [nTPM]":"10.9","Cell RNA - hTCEpi [nTPM]":"8.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.8","Cell RNA - hTERT-HME1 [nTPM]":"7.2","Cell RNA - hTERT-RPE1 [nTPM]":"10.3","Cell RNA - HUVEC TERT2 [nTPM]":"8.9","Cell RNA - JURKAT [nTPM]":"14.8","Cell RNA - K-562 [nTPM]":"14.5","Cell RNA - Karpas-707 [nTPM]":"14.0","Cell RNA - LHCN-M2 [nTPM]":"7.0","Cell RNA - MCF7 [nTPM]":"22.3","Cell RNA - MOLT-4 [nTPM]":"11.4","Cell RNA - NB-4 [nTPM]":"19.9","Cell RNA - NTERA-2 [nTPM]":"8.1","Cell RNA - OE19 [nTPM]":"5.3","Cell RNA - PC-3 [nTPM]":"16.0","Cell RNA - REH [nTPM]":"21.1","Cell RNA - RH-30 [nTPM]":"8.7","Cell RNA - RPMI-8226 [nTPM]":"8.3","Cell RNA - RPTEC TERT1 [nTPM]":"7.4","Cell RNA - RT4 [nTPM]":"9.8","Cell RNA - SCLC-21H [nTPM]":"14.1","Cell RNA - SH-SY5Y [nTPM]":"12.2","Cell RNA - SiHa [nTPM]":"10.4","Cell RNA - SK-BR-3 [nTPM]":"8.5","Cell RNA - SK-MEL-30 [nTPM]":"7.6","Cell RNA - SuSa [nTPM]":"7.6","Cell RNA - T-47d [nTPM]":"15.1","Cell RNA - THP-1 [nTPM]":"15.6","Cell RNA - TIME [nTPM]":"11.8","Cell RNA - U-138 MG [nTPM]":"24.1","Cell RNA - U-2 OS [nTPM]":"9.4","Cell RNA - U-2197 [nTPM]":"10.1","Cell RNA - U-251 MG [nTPM]":"18.2","Cell RNA - U-266\/70 [nTPM]":"11.6","Cell RNA - U-266\/84 [nTPM]":"10.6","Cell RNA - U-698 [nTPM]":"4.5","Cell RNA - U-87 MG [nTPM]":"12.0","Cell RNA - U-937 [nTPM]":"7.8","Cell RNA - WM-115 [nTPM]":"9.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"15.0","Brain RNA - basal ganglia [nTPM]":"15.0","Brain RNA - cerebellum [nTPM]":"15.3","Brain RNA - cerebral cortex [nTPM]":"19.9","Brain RNA - hippocampal formation [nTPM]":"14.0","Brain RNA - hypothalamus [nTPM]":"14.3","Brain RNA - medulla oblongata [nTPM]":"15.1","Brain RNA - midbrain [nTPM]":"13.3","Brain RNA - pons [nTPM]":"15.5","Brain RNA - spinal cord [nTPM]":"11.4","Brain RNA - thalamus [nTPM]":"14.8","Brain RNA - white matter [nTPM]":"13.9","Single Cell Type RNA - Adipocytes [nTPM]":"14.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.9","Single Cell Type RNA - Astrocytes [nTPM]":"17.0","Single Cell Type RNA - B-cells [nTPM]":"5.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"7.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"3.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.3","Single Cell Type RNA - dendritic cells [nTPM]":"7.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.1","Single Cell Type RNA - Endothelial cells [nTPM]":"7.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.1","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.8","Single Cell Type RNA - Fibroblasts [nTPM]":"5.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.8","Single Cell Type RNA - granulocytes [nTPM]":"8.9","Single Cell Type RNA - Granulosa cells [nTPM]":"8.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"3.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.2","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.6","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"3.5","Single Cell Type RNA - Langerhans cells [nTPM]":"3.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"7.5","Single Cell Type RNA - Macrophages [nTPM]":"3.7","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"3.5","Single Cell Type RNA - Muller glia cells [nTPM]":"8.9","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.7","Single Cell Type RNA - Paneth cells [nTPM]":"1.6","Single Cell Type RNA - Peritubular cells [nTPM]":"5.7","Single Cell Type RNA - Plasma cells [nTPM]":"2.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.5","Single Cell Type RNA - Spermatocytes [nTPM]":"15.3","Single Cell Type RNA - Spermatogonia [nTPM]":"9.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"5.3","Single Cell Type RNA - Theca cells [nTPM]":"5.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.9","Single Cell Type RNA - Urothelial cells [nTPM]":"1.6"},{"Gene":"INPP5K","Gene synonym":["SKIP"],"Ensembl":"ENSG00000132376","Gene description":"Inositol polyphosphate-5-phosphatase K","Uniprot":["Q9BT40"],"Chromosome":"17","Position":"1494577-1516742","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Cataract","Congenital muscular dystrophy","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"96.1","Late spermatids":"345.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.91e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.33e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.47e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Tissue RNA - adipose tissue [nTPM]":"34.7","Tissue RNA - adrenal gland [nTPM]":"15.2","Tissue RNA - amygdala [nTPM]":"25.8","Tissue RNA - appendix [nTPM]":"12.9","Tissue RNA - basal ganglia [nTPM]":"26.0","Tissue RNA - bone marrow [nTPM]":"34.5","Tissue RNA - breast [nTPM]":"29.2","Tissue RNA - cerebellum [nTPM]":"25.3","Tissue RNA - cerebral cortex [nTPM]":"30.2","Tissue RNA - cervix [nTPM]":"19.5","Tissue RNA - choroid plexus [nTPM]":"61.5","Tissue RNA - colon [nTPM]":"19.6","Tissue RNA - duodenum [nTPM]":"10.2","Tissue RNA - endometrium 1 [nTPM]":"17.0","Tissue RNA - epididymis [nTPM]":"13.1","Tissue RNA - esophagus [nTPM]":"17.9","Tissue RNA - fallopian tube [nTPM]":"15.3","Tissue RNA - gallbladder [nTPM]":"10.7","Tissue RNA - heart muscle [nTPM]":"28.9","Tissue RNA - hippocampal formation [nTPM]":"29.8","Tissue RNA - hypothalamus [nTPM]":"25.7","Tissue RNA - kidney [nTPM]":"16.7","Tissue RNA - liver [nTPM]":"15.0","Tissue RNA - lung [nTPM]":"27.3","Tissue RNA - lymph node [nTPM]":"18.6","Tissue RNA - medulla oblongata [nTPM]":"26.9","Tissue RNA - midbrain [nTPM]":"26.9","Tissue RNA - ovary [nTPM]":"17.8","Tissue RNA - pancreas [nTPM]":"21.9","Tissue RNA - parathyroid gland [nTPM]":"13.7","Tissue RNA - pituitary gland [nTPM]":"14.8","Tissue RNA - placenta [nTPM]":"18.6","Tissue RNA - pons [nTPM]":"26.9","Tissue RNA - prostate [nTPM]":"19.6","Tissue RNA - rectum [nTPM]":"12.7","Tissue RNA - retina [nTPM]":"15.9","Tissue RNA - salivary gland [nTPM]":"18.1","Tissue RNA - seminal vesicle [nTPM]":"12.9","Tissue RNA - skeletal muscle [nTPM]":"40.5","Tissue RNA - skin 1 [nTPM]":"30.1","Tissue RNA - small intestine [nTPM]":"19.4","Tissue RNA - smooth muscle [nTPM]":"12.0","Tissue RNA - spinal cord [nTPM]":"25.4","Tissue RNA - spleen [nTPM]":"22.8","Tissue RNA - stomach 1 [nTPM]":"19.1","Tissue RNA - testis [nTPM]":"20.4","Tissue RNA - thalamus [nTPM]":"26.9","Tissue RNA - thymus [nTPM]":"25.8","Tissue RNA - thyroid gland [nTPM]":"30.4","Tissue RNA - tongue [nTPM]":"25.2","Tissue RNA - tonsil [nTPM]":"19.7","Tissue RNA - urinary bladder [nTPM]":"18.2","Tissue RNA - vagina [nTPM]":"17.9","Tissue RNA - white matter [nTPM]":"27.0","Cell RNA - A-431 [nTPM]":"14.9","Cell RNA - A549 [nTPM]":"24.0","Cell RNA - AF22 [nTPM]":"9.2","Cell RNA - AN3-CA [nTPM]":"18.4","Cell RNA - ASC diff [nTPM]":"22.5","Cell RNA - ASC TERT1 [nTPM]":"13.2","Cell RNA - BEWO [nTPM]":"12.1","Cell RNA - BJ [nTPM]":"12.0","Cell RNA - BJ hTERT+ [nTPM]":"23.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.6","Cell RNA - CACO-2 [nTPM]":"15.7","Cell RNA - CAPAN-2 [nTPM]":"9.1","Cell RNA - Daudi [nTPM]":"14.6","Cell RNA - EFO-21 [nTPM]":"23.2","Cell RNA - fHDF\/TERT166 [nTPM]":"22.2","Cell RNA - GAMG [nTPM]":"12.5","Cell RNA - HaCaT [nTPM]":"19.4","Cell RNA - HAP1 [nTPM]":"22.1","Cell RNA - HBEC3-KT [nTPM]":"9.6","Cell RNA - HBF TERT88 [nTPM]":"14.3","Cell RNA - HDLM-2 [nTPM]":"35.3","Cell RNA - HEK 293 [nTPM]":"33.0","Cell RNA - HEL [nTPM]":"8.6","Cell RNA - HeLa [nTPM]":"18.1","Cell RNA - Hep G2 [nTPM]":"5.9","Cell RNA - HHSteC [nTPM]":"31.3","Cell RNA - HL-60 [nTPM]":"7.9","Cell RNA - HMC-1 [nTPM]":"17.0","Cell RNA - HSkMC [nTPM]":"16.2","Cell RNA - hTCEpi [nTPM]":"24.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.8","Cell RNA - hTERT-HME1 [nTPM]":"16.1","Cell RNA - hTERT-RPE1 [nTPM]":"10.0","Cell RNA - HUVEC TERT2 [nTPM]":"25.3","Cell RNA - JURKAT [nTPM]":"25.3","Cell RNA - K-562 [nTPM]":"9.4","Cell RNA - Karpas-707 [nTPM]":"25.9","Cell RNA - LHCN-M2 [nTPM]":"10.6","Cell RNA - MCF7 [nTPM]":"12.5","Cell RNA - MOLT-4 [nTPM]":"24.5","Cell RNA - NB-4 [nTPM]":"7.1","Cell RNA - NTERA-2 [nTPM]":"3.9","Cell RNA - OE19 [nTPM]":"23.9","Cell RNA - PC-3 [nTPM]":"14.6","Cell RNA - REH [nTPM]":"19.0","Cell RNA - RH-30 [nTPM]":"6.7","Cell RNA - RPMI-8226 [nTPM]":"14.6","Cell RNA - RPTEC TERT1 [nTPM]":"12.8","Cell RNA - RT4 [nTPM]":"10.3","Cell RNA - SCLC-21H [nTPM]":"7.1","Cell RNA - SH-SY5Y [nTPM]":"18.0","Cell RNA - SiHa [nTPM]":"10.2","Cell RNA - SK-BR-3 [nTPM]":"21.6","Cell RNA - SK-MEL-30 [nTPM]":"24.3","Cell RNA - SuSa [nTPM]":"13.0","Cell RNA - T-47d [nTPM]":"17.9","Cell RNA - THP-1 [nTPM]":"7.3","Cell RNA - TIME [nTPM]":"16.2","Cell RNA - U-138 MG [nTPM]":"13.6","Cell RNA - U-2 OS [nTPM]":"13.3","Cell RNA - U-2197 [nTPM]":"19.8","Cell RNA - U-251 MG [nTPM]":"16.8","Cell RNA - U-266\/70 [nTPM]":"12.9","Cell RNA - U-266\/84 [nTPM]":"23.4","Cell RNA - U-698 [nTPM]":"7.4","Cell RNA - U-87 MG [nTPM]":"14.7","Cell RNA - U-937 [nTPM]":"9.1","Cell RNA - WM-115 [nTPM]":"17.3","Blood RNA - basophil [nTPM]":"104.3","Blood RNA - classical monocyte [nTPM]":"42.2","Blood RNA - eosinophil [nTPM]":"74.3","Blood RNA - gdT-cell [nTPM]":"48.7","Blood RNA - intermediate monocyte [nTPM]":"41.9","Blood RNA - MAIT T-cell [nTPM]":"39.7","Blood RNA - memory B-cell [nTPM]":"27.5","Blood RNA - memory CD4 T-cell [nTPM]":"44.5","Blood RNA - memory CD8 T-cell [nTPM]":"50.2","Blood RNA - myeloid DC [nTPM]":"36.2","Blood RNA - naive B-cell [nTPM]":"24.4","Blood RNA - naive CD4 T-cell [nTPM]":"37.5","Blood RNA - naive CD8 T-cell [nTPM]":"41.1","Blood RNA - neutrophil [nTPM]":"74.7","Blood RNA - NK-cell [nTPM]":"42.3","Blood RNA - non-classical monocyte [nTPM]":"66.6","Blood RNA - plasmacytoid DC [nTPM]":"27.0","Blood RNA - T-reg [nTPM]":"75.1","Blood RNA - total PBMC [nTPM]":"62.5","Brain RNA - amygdala [nTPM]":"25.8","Brain RNA - basal ganglia [nTPM]":"26.0","Brain RNA - cerebellum [nTPM]":"25.3","Brain RNA - cerebral cortex [nTPM]":"30.2","Brain RNA - hippocampal formation [nTPM]":"29.8","Brain RNA - hypothalamus [nTPM]":"25.7","Brain RNA - medulla oblongata [nTPM]":"26.9","Brain RNA - midbrain [nTPM]":"26.9","Brain RNA - pons [nTPM]":"26.9","Brain RNA - spinal cord [nTPM]":"25.4","Brain RNA - thalamus [nTPM]":"26.9","Brain RNA - white matter [nTPM]":"27.0","Single Cell Type RNA - Adipocytes [nTPM]":"26.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.1","Single Cell Type RNA - Astrocytes [nTPM]":"8.5","Single Cell Type RNA - B-cells [nTPM]":"20.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Bipolar cells [nTPM]":"7.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"35.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"11.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.9","Single Cell Type RNA - dendritic cells [nTPM]":"27.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"26.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"19.4","Single Cell Type RNA - Early spermatids [nTPM]":"96.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.9","Single Cell Type RNA - Endothelial cells [nTPM]":"27.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.4","Single Cell Type RNA - Erythroid cells [nTPM]":"25.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"24.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"16.4","Single Cell Type RNA - Fibroblasts [nTPM]":"15.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.4","Single Cell Type RNA - granulocytes [nTPM]":"19.7","Single Cell Type RNA - Granulosa cells [nTPM]":"7.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.5","Single Cell Type RNA - Hepatocytes [nTPM]":"10.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.9","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.3","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"18.4","Single Cell Type RNA - Langerhans cells [nTPM]":"19.0","Single Cell Type RNA - Late spermatids [nTPM]":"345.7","Single Cell Type RNA - Leydig cells [nTPM]":"11.5","Single Cell Type RNA - Macrophages [nTPM]":"13.8","Single Cell Type RNA - Melanocytes [nTPM]":"32.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"37.1","Single Cell Type RNA - Muller glia cells [nTPM]":"23.1","Single Cell Type RNA - NK-cells [nTPM]":"27.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"27.1","Single Cell Type RNA - Paneth cells [nTPM]":"23.4","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"18.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"33.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.9","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.3","Single Cell Type RNA - Spermatocytes [nTPM]":"35.5","Single Cell Type RNA - Spermatogonia [nTPM]":"20.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"30.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"31.1","Single Cell Type RNA - T-cells [nTPM]":"27.2","Single Cell Type RNA - Theca cells [nTPM]":"5.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.5","Single Cell Type RNA - Urothelial cells [nTPM]":"17.4"},{"Gene":"INPPL1","Gene synonym":["SHIP2"],"Ensembl":"ENSG00000165458","Gene description":"Inositol polyphosphate phosphatase like 1","Uniprot":["O15357"],"Chromosome":"11","Position":"72223701-72239147","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell adhesion","Immunity"],"Molecular function":["Actin-binding","Hydrolase"],"Disease involvement":["Cancer-related genes","Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"344.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037601"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA037601":"AB_10672281"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.37e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Tissue RNA - adipose tissue [nTPM]":"45.2","Tissue RNA - adrenal gland [nTPM]":"56.4","Tissue RNA - amygdala [nTPM]":"39.0","Tissue RNA - appendix [nTPM]":"34.4","Tissue RNA - basal ganglia [nTPM]":"43.4","Tissue RNA - bone marrow [nTPM]":"51.3","Tissue RNA - breast [nTPM]":"44.7","Tissue RNA - cerebellum [nTPM]":"41.3","Tissue RNA - cerebral cortex [nTPM]":"40.5","Tissue RNA - cervix [nTPM]":"63.8","Tissue RNA - choroid plexus [nTPM]":"47.3","Tissue RNA - colon [nTPM]":"87.5","Tissue RNA - duodenum [nTPM]":"35.9","Tissue RNA - endometrium 1 [nTPM]":"56.1","Tissue RNA - epididymis [nTPM]":"18.2","Tissue RNA - esophagus [nTPM]":"34.6","Tissue RNA - fallopian tube [nTPM]":"61.3","Tissue RNA - gallbladder [nTPM]":"33.7","Tissue RNA - heart muscle [nTPM]":"73.6","Tissue RNA - hippocampal formation [nTPM]":"33.2","Tissue RNA - hypothalamus [nTPM]":"42.5","Tissue RNA - kidney [nTPM]":"60.0","Tissue RNA - liver [nTPM]":"36.6","Tissue RNA - lung [nTPM]":"61.8","Tissue RNA - lymph node [nTPM]":"36.8","Tissue RNA - medulla oblongata [nTPM]":"53.9","Tissue RNA - midbrain [nTPM]":"43.2","Tissue RNA - ovary [nTPM]":"68.6","Tissue RNA - pancreas [nTPM]":"55.7","Tissue RNA - parathyroid gland [nTPM]":"36.4","Tissue RNA - pituitary gland [nTPM]":"60.5","Tissue RNA - placenta [nTPM]":"39.7","Tissue RNA - pons [nTPM]":"45.8","Tissue RNA - prostate [nTPM]":"68.7","Tissue RNA - rectum [nTPM]":"23.3","Tissue RNA - retina [nTPM]":"14.9","Tissue RNA - salivary gland [nTPM]":"53.8","Tissue RNA - seminal vesicle [nTPM]":"39.5","Tissue RNA - skeletal muscle [nTPM]":"116.6","Tissue RNA - skin 1 [nTPM]":"31.4","Tissue RNA - small intestine [nTPM]":"57.1","Tissue RNA - smooth muscle [nTPM]":"33.4","Tissue RNA - spinal cord [nTPM]":"45.0","Tissue RNA - spleen [nTPM]":"66.1","Tissue RNA - stomach 1 [nTPM]":"60.8","Tissue RNA - testis [nTPM]":"24.2","Tissue RNA - thalamus [nTPM]":"48.8","Tissue RNA - thymus [nTPM]":"19.3","Tissue RNA - thyroid gland [nTPM]":"67.7","Tissue RNA - tongue [nTPM]":"43.0","Tissue RNA - tonsil [nTPM]":"23.2","Tissue RNA - urinary bladder [nTPM]":"59.9","Tissue RNA - vagina [nTPM]":"43.4","Tissue RNA - white matter [nTPM]":"41.2","Cell RNA - A-431 [nTPM]":"28.7","Cell RNA - A549 [nTPM]":"62.1","Cell RNA - AF22 [nTPM]":"71.5","Cell RNA - AN3-CA [nTPM]":"49.8","Cell RNA - ASC diff [nTPM]":"35.4","Cell RNA - ASC TERT1 [nTPM]":"41.1","Cell RNA - BEWO [nTPM]":"122.5","Cell RNA - BJ [nTPM]":"118.9","Cell RNA - BJ hTERT+ [nTPM]":"61.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"80.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"49.6","Cell RNA - CACO-2 [nTPM]":"84.3","Cell RNA - CAPAN-2 [nTPM]":"72.2","Cell RNA - Daudi [nTPM]":"79.5","Cell RNA - EFO-21 [nTPM]":"125.6","Cell RNA - fHDF\/TERT166 [nTPM]":"101.7","Cell RNA - GAMG [nTPM]":"57.8","Cell RNA - HaCaT [nTPM]":"106.7","Cell RNA - HAP1 [nTPM]":"60.4","Cell RNA - HBEC3-KT [nTPM]":"37.6","Cell RNA - HBF TERT88 [nTPM]":"28.0","Cell RNA - HDLM-2 [nTPM]":"101.9","Cell RNA - HEK 293 [nTPM]":"59.1","Cell RNA - HEL [nTPM]":"84.8","Cell RNA - HeLa [nTPM]":"344.5","Cell RNA - Hep G2 [nTPM]":"31.9","Cell RNA - HHSteC [nTPM]":"68.1","Cell RNA - HL-60 [nTPM]":"56.1","Cell RNA - HMC-1 [nTPM]":"176.7","Cell RNA - HSkMC [nTPM]":"58.2","Cell RNA - hTCEpi [nTPM]":"39.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"78.0","Cell RNA - hTERT-HME1 [nTPM]":"31.4","Cell RNA - hTERT-RPE1 [nTPM]":"100.5","Cell RNA - HUVEC TERT2 [nTPM]":"44.2","Cell RNA - JURKAT [nTPM]":"29.3","Cell RNA - K-562 [nTPM]":"59.7","Cell RNA - Karpas-707 [nTPM]":"34.7","Cell RNA - LHCN-M2 [nTPM]":"45.1","Cell RNA - MCF7 [nTPM]":"78.8","Cell RNA - MOLT-4 [nTPM]":"42.1","Cell RNA - NB-4 [nTPM]":"224.9","Cell RNA - NTERA-2 [nTPM]":"67.7","Cell RNA - OE19 [nTPM]":"20.7","Cell RNA - PC-3 [nTPM]":"93.7","Cell RNA - REH [nTPM]":"185.0","Cell RNA - RH-30 [nTPM]":"161.0","Cell RNA - RPMI-8226 [nTPM]":"18.2","Cell RNA - RPTEC TERT1 [nTPM]":"94.8","Cell RNA - RT4 [nTPM]":"48.6","Cell RNA - SCLC-21H [nTPM]":"33.8","Cell RNA - SH-SY5Y [nTPM]":"48.6","Cell RNA - SiHa [nTPM]":"133.9","Cell RNA - SK-BR-3 [nTPM]":"85.1","Cell RNA - SK-MEL-30 [nTPM]":"182.8","Cell RNA - SuSa [nTPM]":"36.6","Cell RNA - T-47d [nTPM]":"88.8","Cell RNA - THP-1 [nTPM]":"106.0","Cell RNA - TIME [nTPM]":"74.5","Cell RNA - U-138 MG [nTPM]":"86.4","Cell RNA - U-2 OS [nTPM]":"96.7","Cell RNA - U-2197 [nTPM]":"129.9","Cell RNA - U-251 MG [nTPM]":"43.1","Cell RNA - U-266\/70 [nTPM]":"94.5","Cell RNA - U-266\/84 [nTPM]":"17.5","Cell RNA - U-698 [nTPM]":"80.1","Cell RNA - U-87 MG [nTPM]":"24.7","Cell RNA - U-937 [nTPM]":"51.7","Cell RNA - WM-115 [nTPM]":"47.2","Blood RNA - basophil [nTPM]":"2.5","Blood RNA - classical monocyte [nTPM]":"3.5","Blood RNA - eosinophil [nTPM]":"3.3","Blood RNA - gdT-cell [nTPM]":"1.9","Blood RNA - intermediate monocyte [nTPM]":"2.0","Blood RNA - MAIT T-cell [nTPM]":"1.7","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.6","Blood RNA - memory CD8 T-cell [nTPM]":"1.3","Blood RNA - myeloid DC [nTPM]":"2.4","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.1","Blood RNA - naive CD8 T-cell [nTPM]":"1.6","Blood RNA - neutrophil [nTPM]":"2.3","Blood RNA - NK-cell [nTPM]":"2.2","Blood RNA - non-classical monocyte [nTPM]":"3.6","Blood RNA - plasmacytoid DC [nTPM]":"1.8","Blood RNA - T-reg [nTPM]":"1.5","Blood RNA - total PBMC [nTPM]":"1.8","Brain RNA - amygdala [nTPM]":"39.0","Brain RNA - basal ganglia [nTPM]":"43.4","Brain RNA - cerebellum [nTPM]":"41.3","Brain RNA - cerebral cortex [nTPM]":"40.5","Brain RNA - hippocampal formation [nTPM]":"33.2","Brain RNA - hypothalamus [nTPM]":"42.5","Brain RNA - medulla oblongata [nTPM]":"53.9","Brain RNA - midbrain [nTPM]":"43.2","Brain RNA - pons [nTPM]":"45.8","Brain RNA - spinal cord [nTPM]":"45.0","Brain RNA - thalamus [nTPM]":"48.8","Brain RNA - white matter [nTPM]":"41.2","Single Cell Type RNA - Adipocytes [nTPM]":"13.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.8","Single Cell Type RNA - Astrocytes [nTPM]":"47.0","Single Cell Type RNA - B-cells [nTPM]":"8.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"1.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"20.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"11.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.9","Single Cell Type RNA - dendritic cells [nTPM]":"9.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"28.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.6","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.3","Single Cell Type RNA - Endothelial cells [nTPM]":"11.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.7","Single Cell Type RNA - Erythroid cells [nTPM]":"5.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.4","Single Cell Type RNA - Fibroblasts [nTPM]":"10.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"24.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.5","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"21.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.9","Single Cell Type RNA - Hepatocytes [nTPM]":"12.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"21.7","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.4","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"27.6","Single Cell Type RNA - Langerhans cells [nTPM]":"16.2","Single Cell Type RNA - Late spermatids [nTPM]":"2.1","Single Cell Type RNA - Leydig cells [nTPM]":"9.9","Single Cell Type RNA - Macrophages [nTPM]":"29.8","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"17.6","Single Cell Type RNA - Muller glia cells [nTPM]":"16.8","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.9","Single Cell Type RNA - Paneth cells [nTPM]":"17.5","Single Cell Type RNA - Peritubular cells [nTPM]":"13.9","Single Cell Type RNA - Plasma cells [nTPM]":"7.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.5","Single Cell Type RNA - Spermatocytes [nTPM]":"1.4","Single Cell Type RNA - Spermatogonia [nTPM]":"4.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"32.4","Single Cell Type RNA - T-cells [nTPM]":"11.6","Single Cell Type RNA - Theca cells [nTPM]":"10.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"21.8","Single Cell Type RNA - Urothelial cells [nTPM]":"5.4"},{"Gene":"IRAK3","Gene synonym":["IRAK-M"],"Ensembl":"ENSG00000090376","Gene description":"Interleukin 1 receptor associated kinase 3","Uniprot":["Q9Y616"],"Chromosome":"12","Position":"66189195-66254622","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Asthma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"78.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"83.3","Kupffer cells":"123.0","Macrophages":"126.3","Microglial cells":"114.3","monocytes":"96.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"12.7","classical monocyte":"23.4","intermediate monocyte":"24.2","myeloid DC":"11.5","neutrophil":"12.9","non-classical monocyte":"42.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"dendritic cells":"11.5","granulocytes":"12.9","monocytes":"42.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"25.9","ASC TERT1":"21.1","HEL":"22.9","HL-60":"30.8","NB-4":"25.1","THP-1":"37.3","U-937":"26.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043097"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA043097":"AB_10795612"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.56e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.23e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Tissue RNA - adipose tissue [nTPM]":"18.7","Tissue RNA - adrenal gland [nTPM]":"3.8","Tissue RNA - amygdala [nTPM]":"3.7","Tissue RNA - appendix [nTPM]":"12.4","Tissue RNA - basal ganglia [nTPM]":"4.1","Tissue RNA - bone marrow [nTPM]":"78.1","Tissue RNA - breast [nTPM]":"11.6","Tissue RNA - cerebellum [nTPM]":"4.1","Tissue RNA - cerebral cortex [nTPM]":"7.5","Tissue RNA - cervix [nTPM]":"9.3","Tissue RNA - choroid plexus [nTPM]":"5.4","Tissue RNA - colon [nTPM]":"4.6","Tissue RNA - duodenum [nTPM]":"1.3","Tissue RNA - endometrium 1 [nTPM]":"4.0","Tissue RNA - epididymis [nTPM]":"3.0","Tissue RNA - esophagus [nTPM]":"3.8","Tissue RNA - fallopian tube [nTPM]":"8.0","Tissue RNA - gallbladder [nTPM]":"6.9","Tissue RNA - heart muscle [nTPM]":"7.9","Tissue RNA - hippocampal formation [nTPM]":"3.2","Tissue RNA - hypothalamus [nTPM]":"4.7","Tissue RNA - kidney [nTPM]":"3.5","Tissue RNA - liver [nTPM]":"2.8","Tissue RNA - lung [nTPM]":"19.0","Tissue RNA - lymph node [nTPM]":"4.1","Tissue RNA - medulla oblongata [nTPM]":"5.6","Tissue RNA - midbrain [nTPM]":"5.7","Tissue RNA - ovary [nTPM]":"3.2","Tissue RNA - pancreas [nTPM]":"2.5","Tissue RNA - parathyroid gland [nTPM]":"0.9","Tissue RNA - pituitary gland [nTPM]":"8.9","Tissue RNA - placenta [nTPM]":"6.8","Tissue RNA - pons [nTPM]":"6.5","Tissue RNA - prostate [nTPM]":"5.3","Tissue RNA - rectum [nTPM]":"2.8","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"6.2","Tissue RNA - seminal vesicle [nTPM]":"5.6","Tissue RNA - skeletal muscle [nTPM]":"2.6","Tissue RNA - skin 1 [nTPM]":"3.4","Tissue RNA - small intestine [nTPM]":"5.6","Tissue RNA - smooth muscle [nTPM]":"5.4","Tissue RNA - spinal cord [nTPM]":"5.0","Tissue RNA - spleen [nTPM]":"27.5","Tissue RNA - stomach 1 [nTPM]":"6.9","Tissue RNA - testis [nTPM]":"1.8","Tissue RNA - thalamus [nTPM]":"5.6","Tissue RNA - thymus [nTPM]":"2.7","Tissue RNA - thyroid gland [nTPM]":"5.0","Tissue RNA - tongue [nTPM]":"4.6","Tissue RNA - tonsil [nTPM]":"3.9","Tissue RNA - urinary bladder [nTPM]":"8.4","Tissue RNA - vagina [nTPM]":"6.6","Tissue RNA - white matter [nTPM]":"5.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"25.9","Cell RNA - ASC TERT1 [nTPM]":"21.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"2.9","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.3","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"2.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.4","Cell RNA - fHDF\/TERT166 [nTPM]":"5.3","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"3.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"1.3","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"22.9","Cell RNA - HeLa [nTPM]":"1.4","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"13.4","Cell RNA - HL-60 [nTPM]":"30.8","Cell RNA - HMC-1 [nTPM]":"4.0","Cell RNA - HSkMC [nTPM]":"13.5","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"7.6","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"1.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"25.1","Cell RNA - NTERA-2 [nTPM]":"1.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"6.4","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"3.3","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"11.6","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"1.2","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"37.3","Cell RNA - TIME [nTPM]":"8.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"2.2","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"26.8","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"12.7","Blood RNA - classical monocyte [nTPM]":"23.4","Blood RNA - eosinophil [nTPM]":"4.3","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"24.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"11.5","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"12.9","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"42.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"7.3","Brain RNA - amygdala [nTPM]":"3.7","Brain RNA - basal ganglia [nTPM]":"4.1","Brain RNA - cerebellum [nTPM]":"4.1","Brain RNA - cerebral cortex [nTPM]":"7.5","Brain RNA - hippocampal formation [nTPM]":"3.2","Brain RNA - hypothalamus [nTPM]":"4.7","Brain RNA - medulla oblongata [nTPM]":"5.6","Brain RNA - midbrain [nTPM]":"5.7","Brain RNA - pons [nTPM]":"6.5","Brain RNA - spinal cord [nTPM]":"5.0","Brain RNA - thalamus [nTPM]":"5.6","Brain RNA - white matter [nTPM]":"5.1","Single Cell Type RNA - Adipocytes [nTPM]":"83.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.4","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"2.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"27.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"46.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"14.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.6","Single Cell Type RNA - Early spermatids [nTPM]":"6.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.5","Single Cell Type RNA - Endothelial cells [nTPM]":"38.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"9.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"22.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"27.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"36.4","Single Cell Type RNA - Hepatocytes [nTPM]":"1.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.1","Single Cell Type RNA - Ionocytes [nTPM]":"36.7","Single Cell Type RNA - Kupffer cells [nTPM]":"123.0","Single Cell Type RNA - Langerhans cells [nTPM]":"12.1","Single Cell Type RNA - Late spermatids [nTPM]":"5.3","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"126.3","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"114.3","Single Cell Type RNA - monocytes [nTPM]":"96.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"11.3","Single Cell Type RNA - Plasma cells [nTPM]":"9.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"35.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"1.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"3.5","Single Cell Type RNA - Theca cells [nTPM]":"12.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.7","Single Cell Type RNA - Urothelial cells [nTPM]":"2.5"},{"Gene":"IRAK4","Gene synonym":["NY-REN-64"],"Ensembl":"ENSG00000198001","Gene description":"Interleukin 1 receptor associated kinase 4","Uniprot":["Q9NWZ3"],"Chromosome":"12","Position":"43758944-43789543","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Immunity","Innate immunity"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-937":"56.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016685","CAB022077"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Microtubules","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Microtubules"],"Subcellular additional location":["Nucleoli","Cytosol"],"Antibody RRID":{"CAB016685":"AB_1618505","CAB022077":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.46e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.42e-5"},"Tissue RNA - adipose tissue [nTPM]":"8.6","Tissue RNA - adrenal gland [nTPM]":"6.5","Tissue RNA - amygdala [nTPM]":"4.0","Tissue RNA - appendix [nTPM]":"13.6","Tissue RNA - basal ganglia [nTPM]":"4.6","Tissue RNA - bone marrow [nTPM]":"10.0","Tissue RNA - breast [nTPM]":"8.9","Tissue RNA - cerebellum [nTPM]":"4.5","Tissue RNA - cerebral cortex [nTPM]":"5.1","Tissue RNA - cervix [nTPM]":"7.9","Tissue RNA - choroid plexus [nTPM]":"5.1","Tissue RNA - colon [nTPM]":"7.9","Tissue RNA - duodenum [nTPM]":"9.1","Tissue RNA - endometrium 1 [nTPM]":"6.8","Tissue RNA - epididymis [nTPM]":"7.0","Tissue RNA - esophagus [nTPM]":"10.5","Tissue RNA - fallopian tube [nTPM]":"7.0","Tissue RNA - gallbladder [nTPM]":"8.8","Tissue RNA - heart muscle [nTPM]":"5.4","Tissue RNA - hippocampal formation [nTPM]":"3.9","Tissue RNA - hypothalamus [nTPM]":"4.6","Tissue RNA - kidney [nTPM]":"8.0","Tissue RNA - liver [nTPM]":"9.2","Tissue RNA - lung [nTPM]":"8.5","Tissue RNA - lymph node [nTPM]":"17.5","Tissue RNA - medulla oblongata [nTPM]":"5.5","Tissue RNA - midbrain [nTPM]":"4.7","Tissue RNA - ovary [nTPM]":"5.6","Tissue RNA - pancreas [nTPM]":"15.1","Tissue RNA - parathyroid gland [nTPM]":"6.9","Tissue RNA - pituitary gland [nTPM]":"6.2","Tissue RNA - placenta [nTPM]":"8.3","Tissue RNA - pons [nTPM]":"5.4","Tissue RNA - prostate [nTPM]":"7.5","Tissue RNA - rectum [nTPM]":"8.4","Tissue RNA - retina [nTPM]":"12.3","Tissue RNA - salivary gland [nTPM]":"8.4","Tissue RNA - seminal vesicle [nTPM]":"7.0","Tissue RNA - skeletal muscle [nTPM]":"3.0","Tissue RNA - skin 1 [nTPM]":"13.3","Tissue RNA - small intestine [nTPM]":"11.9","Tissue RNA - smooth muscle [nTPM]":"7.2","Tissue RNA - spinal cord [nTPM]":"4.8","Tissue RNA - spleen [nTPM]":"18.6","Tissue RNA - stomach 1 [nTPM]":"10.5","Tissue RNA - testis [nTPM]":"5.8","Tissue RNA - thalamus [nTPM]":"4.9","Tissue RNA - thymus [nTPM]":"18.5","Tissue RNA - thyroid gland [nTPM]":"10.9","Tissue RNA - tongue [nTPM]":"3.2","Tissue RNA - tonsil [nTPM]":"16.3","Tissue RNA - urinary bladder [nTPM]":"7.8","Tissue RNA - vagina [nTPM]":"7.9","Tissue RNA - white matter [nTPM]":"5.3","Cell RNA - A-431 [nTPM]":"9.3","Cell RNA - A549 [nTPM]":"6.8","Cell RNA - AF22 [nTPM]":"4.7","Cell RNA - AN3-CA [nTPM]":"6.2","Cell RNA - ASC diff [nTPM]":"16.5","Cell RNA - ASC TERT1 [nTPM]":"27.6","Cell RNA - BEWO [nTPM]":"6.7","Cell RNA - BJ [nTPM]":"12.9","Cell RNA - BJ hTERT+ [nTPM]":"9.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.1","Cell RNA - CACO-2 [nTPM]":"5.8","Cell RNA - CAPAN-2 [nTPM]":"8.7","Cell RNA - Daudi [nTPM]":"15.8","Cell RNA - EFO-21 [nTPM]":"12.4","Cell RNA - fHDF\/TERT166 [nTPM]":"10.7","Cell RNA - GAMG [nTPM]":"6.6","Cell RNA - HaCaT [nTPM]":"7.5","Cell RNA - HAP1 [nTPM]":"5.3","Cell RNA - HBEC3-KT [nTPM]":"8.3","Cell RNA - HBF TERT88 [nTPM]":"14.2","Cell RNA - HDLM-2 [nTPM]":"22.8","Cell RNA - HEK 293 [nTPM]":"4.9","Cell RNA - HEL [nTPM]":"15.2","Cell RNA - HeLa [nTPM]":"5.2","Cell RNA - Hep G2 [nTPM]":"3.7","Cell RNA - HHSteC [nTPM]":"9.4","Cell RNA - HL-60 [nTPM]":"21.2","Cell RNA - HMC-1 [nTPM]":"17.7","Cell RNA - HSkMC [nTPM]":"14.7","Cell RNA - hTCEpi [nTPM]":"12.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.7","Cell RNA - hTERT-HME1 [nTPM]":"7.4","Cell RNA - hTERT-RPE1 [nTPM]":"17.4","Cell RNA - HUVEC TERT2 [nTPM]":"15.0","Cell RNA - JURKAT [nTPM]":"15.1","Cell RNA - K-562 [nTPM]":"14.4","Cell RNA - Karpas-707 [nTPM]":"11.6","Cell RNA - LHCN-M2 [nTPM]":"27.8","Cell RNA - MCF7 [nTPM]":"5.1","Cell RNA - MOLT-4 [nTPM]":"18.6","Cell RNA - NB-4 [nTPM]":"11.7","Cell RNA - NTERA-2 [nTPM]":"1.7","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"7.9","Cell RNA - REH [nTPM]":"12.2","Cell RNA - RH-30 [nTPM]":"5.8","Cell RNA - RPMI-8226 [nTPM]":"8.4","Cell RNA - RPTEC TERT1 [nTPM]":"7.8","Cell RNA - RT4 [nTPM]":"8.8","Cell RNA - SCLC-21H [nTPM]":"3.4","Cell RNA - SH-SY5Y [nTPM]":"3.3","Cell RNA - SiHa [nTPM]":"6.3","Cell RNA - SK-BR-3 [nTPM]":"7.9","Cell RNA - SK-MEL-30 [nTPM]":"6.2","Cell RNA - SuSa [nTPM]":"6.4","Cell RNA - T-47d [nTPM]":"9.9","Cell RNA - THP-1 [nTPM]":"18.5","Cell RNA - TIME [nTPM]":"13.4","Cell RNA - U-138 MG [nTPM]":"12.2","Cell RNA - U-2 OS [nTPM]":"2.3","Cell RNA - U-2197 [nTPM]":"15.1","Cell RNA - U-251 MG [nTPM]":"9.0","Cell RNA - U-266\/70 [nTPM]":"14.0","Cell RNA - U-266\/84 [nTPM]":"19.4","Cell RNA - U-698 [nTPM]":"13.7","Cell RNA - U-87 MG [nTPM]":"12.7","Cell RNA - U-937 [nTPM]":"56.2","Cell RNA - WM-115 [nTPM]":"6.9","Blood RNA - basophil [nTPM]":"20.8","Blood RNA - classical monocyte [nTPM]":"4.0","Blood RNA - eosinophil [nTPM]":"8.7","Blood RNA - gdT-cell [nTPM]":"6.1","Blood RNA - intermediate monocyte [nTPM]":"4.6","Blood RNA - MAIT T-cell [nTPM]":"6.3","Blood RNA - memory B-cell [nTPM]":"3.3","Blood RNA - memory CD4 T-cell [nTPM]":"4.9","Blood RNA - memory CD8 T-cell [nTPM]":"5.3","Blood RNA - myeloid DC [nTPM]":"3.7","Blood RNA - naive B-cell [nTPM]":"4.4","Blood RNA - naive CD4 T-cell [nTPM]":"4.4","Blood RNA - naive CD8 T-cell [nTPM]":"4.8","Blood RNA - neutrophil [nTPM]":"7.9","Blood RNA - NK-cell [nTPM]":"7.9","Blood RNA - non-classical monocyte [nTPM]":"5.9","Blood RNA - plasmacytoid DC [nTPM]":"5.1","Blood RNA - T-reg [nTPM]":"6.7","Blood RNA - total PBMC [nTPM]":"4.6","Brain RNA - amygdala [nTPM]":"4.0","Brain RNA - basal ganglia [nTPM]":"4.6","Brain RNA - cerebellum [nTPM]":"4.5","Brain RNA - cerebral cortex [nTPM]":"5.1","Brain RNA - hippocampal formation [nTPM]":"3.9","Brain RNA - hypothalamus [nTPM]":"4.6","Brain RNA - medulla oblongata [nTPM]":"5.5","Brain RNA - midbrain [nTPM]":"4.7","Brain RNA - pons [nTPM]":"5.4","Brain RNA - spinal cord [nTPM]":"4.8","Brain RNA - thalamus [nTPM]":"4.9","Brain RNA - white matter [nTPM]":"5.3","Single Cell Type RNA - Adipocytes [nTPM]":"24.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.6","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"36.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Bipolar cells [nTPM]":"5.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"11.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.9","Single Cell Type RNA - dendritic cells [nTPM]":"52.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"12.7","Single Cell Type RNA - Early spermatids [nTPM]":"18.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.4","Single Cell Type RNA - Endothelial cells [nTPM]":"17.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"12.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.4","Single Cell Type RNA - Fibroblasts [nTPM]":"13.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"33.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.2","Single Cell Type RNA - granulocytes [nTPM]":"22.1","Single Cell Type RNA - Granulosa cells [nTPM]":"10.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.1","Single Cell Type RNA - Hepatocytes [nTPM]":"8.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.9","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.9","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"24.7","Single Cell Type RNA - Langerhans cells [nTPM]":"20.2","Single Cell Type RNA - Late spermatids [nTPM]":"23.2","Single Cell Type RNA - Leydig cells [nTPM]":"12.5","Single Cell Type RNA - Macrophages [nTPM]":"25.1","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"28.2","Single Cell Type RNA - Muller glia cells [nTPM]":"9.9","Single Cell Type RNA - NK-cells [nTPM]":"60.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.3","Single Cell Type RNA - Paneth cells [nTPM]":"7.2","Single Cell Type RNA - Peritubular cells [nTPM]":"11.3","Single Cell Type RNA - Plasma cells [nTPM]":"33.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"27.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.0","Single Cell Type RNA - Spermatocytes [nTPM]":"28.2","Single Cell Type RNA - Spermatogonia [nTPM]":"12.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"27.9","Single Cell Type RNA - T-cells [nTPM]":"41.1","Single Cell Type RNA - Theca cells [nTPM]":"15.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.2","Single Cell Type RNA - Urothelial cells [nTPM]":"13.5"},{"Gene":"IRF2BPL","Gene synonym":["C14orf4","EAP1","KIAA1865"],"Ensembl":"ENSG00000119669","Gene description":"Interferon regulatory factor 2 binding protein like","Uniprot":["Q9H1B7"],"Chromosome":"14","Position":"77024543-77028708","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050862","HPA061333"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA050862":"AB_2681258","HPA061333":"AB_2684481"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.52e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Tissue RNA - adipose tissue [nTPM]":"26.1","Tissue RNA - adrenal gland [nTPM]":"25.3","Tissue RNA - amygdala [nTPM]":"12.2","Tissue RNA - appendix [nTPM]":"9.2","Tissue RNA - basal ganglia [nTPM]":"13.9","Tissue RNA - bone marrow [nTPM]":"5.6","Tissue RNA - breast [nTPM]":"28.5","Tissue RNA - cerebellum [nTPM]":"13.4","Tissue RNA - cerebral cortex [nTPM]":"12.0","Tissue RNA - cervix [nTPM]":"20.1","Tissue RNA - choroid plexus [nTPM]":"12.8","Tissue RNA - colon [nTPM]":"32.4","Tissue RNA - duodenum [nTPM]":"6.9","Tissue RNA - endometrium 1 [nTPM]":"25.8","Tissue RNA - epididymis [nTPM]":"5.1","Tissue RNA - esophagus [nTPM]":"13.3","Tissue RNA - fallopian tube [nTPM]":"33.7","Tissue RNA - gallbladder [nTPM]":"6.5","Tissue RNA - heart muscle [nTPM]":"22.6","Tissue RNA - hippocampal formation [nTPM]":"14.1","Tissue RNA - hypothalamus [nTPM]":"21.1","Tissue RNA - kidney [nTPM]":"28.7","Tissue RNA - liver [nTPM]":"19.1","Tissue RNA - lung [nTPM]":"20.9","Tissue RNA - lymph node [nTPM]":"6.2","Tissue RNA - medulla oblongata [nTPM]":"15.2","Tissue RNA - midbrain [nTPM]":"14.8","Tissue RNA - ovary [nTPM]":"32.4","Tissue RNA - pancreas [nTPM]":"17.5","Tissue RNA - parathyroid gland [nTPM]":"19.8","Tissue RNA - pituitary gland [nTPM]":"22.6","Tissue RNA - placenta [nTPM]":"7.9","Tissue RNA - pons [nTPM]":"10.9","Tissue RNA - prostate [nTPM]":"18.4","Tissue RNA - rectum [nTPM]":"3.3","Tissue RNA - retina [nTPM]":"7.3","Tissue RNA - salivary gland [nTPM]":"19.2","Tissue RNA - seminal vesicle [nTPM]":"10.1","Tissue RNA - skeletal muscle [nTPM]":"16.8","Tissue RNA - skin 1 [nTPM]":"25.2","Tissue RNA - small intestine [nTPM]":"15.1","Tissue RNA - smooth muscle [nTPM]":"8.0","Tissue RNA - spinal cord [nTPM]":"12.6","Tissue RNA - spleen [nTPM]":"19.0","Tissue RNA - stomach 1 [nTPM]":"18.8","Tissue RNA - testis [nTPM]":"13.5","Tissue RNA - thalamus [nTPM]":"19.0","Tissue RNA - thymus [nTPM]":"9.7","Tissue RNA - thyroid gland [nTPM]":"18.7","Tissue RNA - tongue [nTPM]":"4.2","Tissue RNA - tonsil [nTPM]":"3.3","Tissue RNA - urinary bladder [nTPM]":"26.4","Tissue RNA - vagina [nTPM]":"18.2","Tissue RNA - white matter [nTPM]":"9.4","Cell RNA - A-431 [nTPM]":"15.4","Cell RNA - A549 [nTPM]":"13.2","Cell RNA - AF22 [nTPM]":"32.2","Cell RNA - AN3-CA [nTPM]":"36.3","Cell RNA - ASC diff [nTPM]":"9.6","Cell RNA - ASC TERT1 [nTPM]":"8.8","Cell RNA - BEWO [nTPM]":"45.8","Cell RNA - BJ [nTPM]":"15.9","Cell RNA - BJ hTERT+ [nTPM]":"13.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.9","Cell RNA - CACO-2 [nTPM]":"6.2","Cell RNA - CAPAN-2 [nTPM]":"24.8","Cell RNA - Daudi [nTPM]":"5.4","Cell RNA - EFO-21 [nTPM]":"11.3","Cell RNA - fHDF\/TERT166 [nTPM]":"13.6","Cell RNA - GAMG [nTPM]":"12.4","Cell RNA - HaCaT [nTPM]":"23.6","Cell RNA - HAP1 [nTPM]":"5.6","Cell RNA - HBEC3-KT [nTPM]":"11.8","Cell RNA - HBF TERT88 [nTPM]":"3.7","Cell RNA - HDLM-2 [nTPM]":"25.8","Cell RNA - HEK 293 [nTPM]":"19.1","Cell RNA - HEL [nTPM]":"6.9","Cell RNA - HeLa [nTPM]":"13.0","Cell RNA - Hep G2 [nTPM]":"8.5","Cell RNA - HHSteC [nTPM]":"12.5","Cell RNA - HL-60 [nTPM]":"1.9","Cell RNA - HMC-1 [nTPM]":"29.7","Cell RNA - HSkMC [nTPM]":"11.8","Cell RNA - hTCEpi [nTPM]":"9.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.8","Cell RNA - hTERT-HME1 [nTPM]":"6.8","Cell RNA - hTERT-RPE1 [nTPM]":"34.8","Cell RNA - HUVEC TERT2 [nTPM]":"6.0","Cell RNA - JURKAT [nTPM]":"10.9","Cell RNA - K-562 [nTPM]":"10.4","Cell RNA - Karpas-707 [nTPM]":"59.4","Cell RNA - LHCN-M2 [nTPM]":"5.7","Cell RNA - MCF7 [nTPM]":"42.2","Cell RNA - MOLT-4 [nTPM]":"21.0","Cell RNA - NB-4 [nTPM]":"14.5","Cell RNA - NTERA-2 [nTPM]":"14.5","Cell RNA - OE19 [nTPM]":"6.6","Cell RNA - PC-3 [nTPM]":"68.2","Cell RNA - REH [nTPM]":"4.4","Cell RNA - RH-30 [nTPM]":"9.1","Cell RNA - RPMI-8226 [nTPM]":"13.0","Cell RNA - RPTEC TERT1 [nTPM]":"15.6","Cell RNA - RT4 [nTPM]":"22.4","Cell RNA - SCLC-21H [nTPM]":"24.9","Cell RNA - SH-SY5Y [nTPM]":"36.0","Cell RNA - SiHa [nTPM]":"22.5","Cell RNA - SK-BR-3 [nTPM]":"23.2","Cell RNA - SK-MEL-30 [nTPM]":"42.5","Cell RNA - SuSa [nTPM]":"8.6","Cell RNA - T-47d [nTPM]":"16.1","Cell RNA - THP-1 [nTPM]":"3.4","Cell RNA - TIME [nTPM]":"10.4","Cell RNA - U-138 MG [nTPM]":"20.2","Cell RNA - U-2 OS [nTPM]":"19.5","Cell RNA - U-2197 [nTPM]":"6.8","Cell RNA - U-251 MG [nTPM]":"10.3","Cell RNA - U-266\/70 [nTPM]":"22.9","Cell RNA - U-266\/84 [nTPM]":"26.3","Cell RNA - U-698 [nTPM]":"9.0","Cell RNA - U-87 MG [nTPM]":"31.3","Cell RNA - U-937 [nTPM]":"4.7","Cell RNA - WM-115 [nTPM]":"25.8","Blood RNA - basophil [nTPM]":"1.7","Blood RNA - classical monocyte [nTPM]":"1.4","Blood RNA - eosinophil [nTPM]":"1.3","Blood RNA - gdT-cell [nTPM]":"2.8","Blood RNA - intermediate monocyte [nTPM]":"1.9","Blood RNA - MAIT T-cell [nTPM]":"2.7","Blood RNA - memory B-cell [nTPM]":"1.4","Blood RNA - memory CD4 T-cell [nTPM]":"2.5","Blood RNA - memory CD8 T-cell [nTPM]":"2.6","Blood RNA - myeloid DC [nTPM]":"1.3","Blood RNA - naive B-cell [nTPM]":"1.6","Blood RNA - naive CD4 T-cell [nTPM]":"2.0","Blood RNA - naive CD8 T-cell [nTPM]":"2.3","Blood RNA - neutrophil [nTPM]":"9.0","Blood RNA - NK-cell [nTPM]":"5.9","Blood RNA - non-classical monocyte [nTPM]":"2.3","Blood RNA - plasmacytoid DC [nTPM]":"10.7","Blood RNA - T-reg [nTPM]":"2.6","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"12.2","Brain RNA - basal ganglia [nTPM]":"13.9","Brain RNA - cerebellum [nTPM]":"13.4","Brain RNA - cerebral cortex [nTPM]":"12.0","Brain RNA - hippocampal formation [nTPM]":"14.1","Brain RNA - hypothalamus [nTPM]":"21.1","Brain RNA - medulla oblongata [nTPM]":"15.2","Brain RNA - midbrain [nTPM]":"14.8","Brain RNA - pons [nTPM]":"10.9","Brain RNA - spinal cord [nTPM]":"12.6","Brain RNA - thalamus [nTPM]":"19.0","Brain RNA - white matter [nTPM]":"9.4","Single Cell Type RNA - Adipocytes [nTPM]":"71.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.3","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"40.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"73.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"115.5","Single Cell Type RNA - Bipolar cells [nTPM]":"57.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"54.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"41.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"11.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"64.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"22.8","Single Cell Type RNA - dendritic cells [nTPM]":"58.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"37.2","Single Cell Type RNA - Ductal cells [nTPM]":"19.6","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.0","Single Cell Type RNA - Endothelial cells [nTPM]":"44.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"47.6","Single Cell Type RNA - Erythroid cells [nTPM]":"10.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"49.7","Single Cell Type RNA - Fibroblasts [nTPM]":"47.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.6","Single Cell Type RNA - granulocytes [nTPM]":"26.6","Single Cell Type RNA - Granulosa cells [nTPM]":"15.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"55.6","Single Cell Type RNA - Hepatocytes [nTPM]":"60.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"33.3","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.7","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"54.7","Single Cell Type RNA - Langerhans cells [nTPM]":"78.9","Single Cell Type RNA - Late spermatids [nTPM]":"4.0","Single Cell Type RNA - Leydig cells [nTPM]":"30.1","Single Cell Type RNA - Macrophages [nTPM]":"26.6","Single Cell Type RNA - Melanocytes [nTPM]":"35.6","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"10.0","Single Cell Type RNA - Muller glia cells [nTPM]":"57.8","Single Cell Type RNA - NK-cells [nTPM]":"38.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.8","Single Cell Type RNA - Paneth cells [nTPM]":"7.0","Single Cell Type RNA - Peritubular cells [nTPM]":"34.3","Single Cell Type RNA - Plasma cells [nTPM]":"21.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"56.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"83.2","Single Cell Type RNA - Spermatocytes [nTPM]":"1.6","Single Cell Type RNA - Spermatogonia [nTPM]":"50.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"54.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"50.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"46.0","Single Cell Type RNA - T-cells [nTPM]":"39.0","Single Cell Type RNA - Theca cells [nTPM]":"27.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.8","Single Cell Type RNA - Urothelial cells [nTPM]":"20.6"},{"Gene":"ITCH","Gene synonym":["AIP4"],"Ensembl":"ENSG00000078747","Gene description":"Itchy E3 ubiquitin protein ligase","Uniprot":["Q96J02"],"Chromosome":"20","Position":"34363241-34540748","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Antiviral defense","Apoptosis","Host-virus interaction","Immunity","Innate immunity","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"139.7","Oligodendrocytes":"260.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021126","HPA049032","CAB072824","CAB072825"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB072824":null,"CAB072825":null,"HPA021126":"AB_1851941","HPA049032":"AB_2680607"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Tissue RNA - adipose tissue [nTPM]":"19.5","Tissue RNA - adrenal gland [nTPM]":"16.2","Tissue RNA - amygdala [nTPM]":"13.7","Tissue RNA - appendix [nTPM]":"18.1","Tissue RNA - basal ganglia [nTPM]":"27.1","Tissue RNA - bone marrow [nTPM]":"27.3","Tissue RNA - breast [nTPM]":"20.0","Tissue RNA - cerebellum [nTPM]":"19.6","Tissue RNA - cerebral cortex [nTPM]":"17.7","Tissue RNA - cervix [nTPM]":"24.5","Tissue RNA - choroid plexus [nTPM]":"17.7","Tissue RNA - colon [nTPM]":"21.6","Tissue RNA - duodenum [nTPM]":"20.2","Tissue RNA - endometrium 1 [nTPM]":"19.4","Tissue RNA - epididymis [nTPM]":"16.6","Tissue RNA - esophagus [nTPM]":"42.8","Tissue RNA - fallopian tube [nTPM]":"15.7","Tissue RNA - gallbladder [nTPM]":"17.0","Tissue RNA - heart muscle [nTPM]":"20.2","Tissue RNA - hippocampal formation [nTPM]":"14.7","Tissue RNA - hypothalamus [nTPM]":"15.9","Tissue RNA - kidney [nTPM]":"23.3","Tissue RNA - liver [nTPM]":"55.6","Tissue RNA - lung [nTPM]":"18.7","Tissue RNA - lymph node [nTPM]":"21.4","Tissue RNA - medulla oblongata [nTPM]":"19.8","Tissue RNA - midbrain [nTPM]":"20.0","Tissue RNA - ovary [nTPM]":"18.8","Tissue RNA - pancreas [nTPM]":"16.5","Tissue RNA - parathyroid gland [nTPM]":"23.1","Tissue RNA - pituitary gland [nTPM]":"7.8","Tissue RNA - placenta [nTPM]":"25.6","Tissue RNA - pons [nTPM]":"21.0","Tissue RNA - prostate [nTPM]":"19.6","Tissue RNA - rectum [nTPM]":"23.5","Tissue RNA - retina [nTPM]":"25.6","Tissue RNA - salivary gland [nTPM]":"18.7","Tissue RNA - seminal vesicle [nTPM]":"19.9","Tissue RNA - skeletal muscle [nTPM]":"17.2","Tissue RNA - skin 1 [nTPM]":"14.0","Tissue RNA - small intestine [nTPM]":"20.9","Tissue RNA - smooth muscle [nTPM]":"21.5","Tissue RNA - spinal cord [nTPM]":"15.9","Tissue RNA - spleen [nTPM]":"20.4","Tissue RNA - stomach 1 [nTPM]":"20.9","Tissue RNA - testis [nTPM]":"38.5","Tissue RNA - thalamus [nTPM]":"20.2","Tissue RNA - thymus [nTPM]":"23.2","Tissue RNA - thyroid gland [nTPM]":"26.3","Tissue RNA - tongue [nTPM]":"21.7","Tissue RNA - tonsil [nTPM]":"25.7","Tissue RNA - urinary bladder [nTPM]":"30.6","Tissue RNA - vagina [nTPM]":"14.8","Tissue RNA - white matter [nTPM]":"45.7","Cell RNA - A-431 [nTPM]":"55.5","Cell RNA - A549 [nTPM]":"34.6","Cell RNA - AF22 [nTPM]":"35.2","Cell RNA - AN3-CA [nTPM]":"25.9","Cell RNA - ASC diff [nTPM]":"38.3","Cell RNA - ASC TERT1 [nTPM]":"57.4","Cell RNA - BEWO [nTPM]":"42.7","Cell RNA - BJ [nTPM]":"43.5","Cell RNA - BJ hTERT+ [nTPM]":"52.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"56.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"54.0","Cell RNA - CACO-2 [nTPM]":"101.5","Cell RNA - CAPAN-2 [nTPM]":"83.8","Cell RNA - Daudi [nTPM]":"26.7","Cell RNA - EFO-21 [nTPM]":"42.1","Cell RNA - fHDF\/TERT166 [nTPM]":"55.6","Cell RNA - GAMG [nTPM]":"73.9","Cell RNA - HaCaT [nTPM]":"66.2","Cell RNA - HAP1 [nTPM]":"54.9","Cell RNA - HBEC3-KT [nTPM]":"92.3","Cell RNA - HBF TERT88 [nTPM]":"66.2","Cell RNA - HDLM-2 [nTPM]":"20.8","Cell RNA - HEK 293 [nTPM]":"17.9","Cell RNA - HEL [nTPM]":"78.3","Cell RNA - HeLa [nTPM]":"28.2","Cell RNA - Hep G2 [nTPM]":"59.3","Cell RNA - HHSteC [nTPM]":"43.9","Cell RNA - HL-60 [nTPM]":"32.6","Cell RNA - HMC-1 [nTPM]":"34.4","Cell RNA - HSkMC [nTPM]":"31.7","Cell RNA - hTCEpi [nTPM]":"46.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"44.4","Cell RNA - hTERT-HME1 [nTPM]":"72.2","Cell RNA - hTERT-RPE1 [nTPM]":"49.8","Cell RNA - HUVEC TERT2 [nTPM]":"41.7","Cell RNA - JURKAT [nTPM]":"40.6","Cell RNA - K-562 [nTPM]":"45.5","Cell RNA - Karpas-707 [nTPM]":"45.7","Cell RNA - LHCN-M2 [nTPM]":"46.2","Cell RNA - MCF7 [nTPM]":"26.5","Cell RNA - MOLT-4 [nTPM]":"49.2","Cell RNA - NB-4 [nTPM]":"18.8","Cell RNA - NTERA-2 [nTPM]":"16.9","Cell RNA - OE19 [nTPM]":"35.6","Cell RNA - PC-3 [nTPM]":"44.2","Cell RNA - REH [nTPM]":"40.9","Cell RNA - RH-30 [nTPM]":"76.3","Cell RNA - RPMI-8226 [nTPM]":"63.6","Cell RNA - RPTEC TERT1 [nTPM]":"34.7","Cell RNA - RT4 [nTPM]":"91.2","Cell RNA - SCLC-21H [nTPM]":"21.4","Cell RNA - SH-SY5Y [nTPM]":"16.4","Cell RNA - SiHa [nTPM]":"82.0","Cell RNA - SK-BR-3 [nTPM]":"32.7","Cell RNA - SK-MEL-30 [nTPM]":"51.0","Cell RNA - SuSa [nTPM]":"33.9","Cell RNA - T-47d [nTPM]":"38.3","Cell RNA - THP-1 [nTPM]":"31.1","Cell RNA - TIME [nTPM]":"39.5","Cell RNA - U-138 MG [nTPM]":"61.5","Cell RNA - U-2 OS [nTPM]":"36.0","Cell RNA - U-2197 [nTPM]":"42.8","Cell RNA - U-251 MG [nTPM]":"33.3","Cell RNA - U-266\/70 [nTPM]":"36.2","Cell RNA - U-266\/84 [nTPM]":"40.5","Cell RNA - U-698 [nTPM]":"40.0","Cell RNA - U-87 MG [nTPM]":"41.0","Cell RNA - U-937 [nTPM]":"21.6","Cell RNA - WM-115 [nTPM]":"38.0","Blood RNA - basophil [nTPM]":"4.6","Blood RNA - classical monocyte [nTPM]":"6.7","Blood RNA - eosinophil [nTPM]":"7.0","Blood RNA - gdT-cell [nTPM]":"12.0","Blood RNA - intermediate monocyte [nTPM]":"7.0","Blood RNA - MAIT T-cell [nTPM]":"12.5","Blood RNA - memory B-cell [nTPM]":"9.2","Blood RNA - memory CD4 T-cell [nTPM]":"4.2","Blood RNA - memory CD8 T-cell [nTPM]":"6.1","Blood RNA - myeloid DC [nTPM]":"4.9","Blood RNA - naive B-cell [nTPM]":"7.8","Blood RNA - naive CD4 T-cell [nTPM]":"3.7","Blood RNA - naive CD8 T-cell [nTPM]":"5.7","Blood RNA - neutrophil [nTPM]":"20.2","Blood RNA - NK-cell [nTPM]":"7.6","Blood RNA - non-classical monocyte [nTPM]":"4.9","Blood RNA - plasmacytoid DC [nTPM]":"14.3","Blood RNA - T-reg [nTPM]":"5.8","Blood RNA - total PBMC [nTPM]":"4.3","Brain RNA - amygdala [nTPM]":"13.7","Brain RNA - basal ganglia [nTPM]":"27.1","Brain RNA - cerebellum [nTPM]":"19.6","Brain RNA - cerebral cortex [nTPM]":"17.7","Brain RNA - hippocampal formation [nTPM]":"14.7","Brain RNA - hypothalamus [nTPM]":"15.9","Brain RNA - medulla oblongata [nTPM]":"19.8","Brain RNA - midbrain [nTPM]":"20.0","Brain RNA - pons [nTPM]":"21.0","Brain RNA - spinal cord [nTPM]":"15.9","Brain RNA - thalamus [nTPM]":"20.2","Brain RNA - white matter [nTPM]":"45.7","Single Cell Type RNA - Adipocytes [nTPM]":"26.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.8","Single Cell Type RNA - Astrocytes [nTPM]":"56.5","Single Cell Type RNA - B-cells [nTPM]":"33.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.6","Single Cell Type RNA - Bipolar cells [nTPM]":"19.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"25.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"17.5","Single Cell Type RNA - dendritic cells [nTPM]":"46.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"28.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"12.8","Single Cell Type RNA - Early spermatids [nTPM]":"59.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"26.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"34.6","Single Cell Type RNA - Endothelial cells [nTPM]":"20.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.0","Single Cell Type RNA - Erythroid cells [nTPM]":"26.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"85.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.2","Single Cell Type RNA - Fibroblasts [nTPM]":"24.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"33.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"36.1","Single Cell Type RNA - granulocytes [nTPM]":"19.0","Single Cell Type RNA - Granulosa cells [nTPM]":"17.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.2","Single Cell Type RNA - Hepatocytes [nTPM]":"53.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.8","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"72.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.9","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"24.3","Single Cell Type RNA - Langerhans cells [nTPM]":"26.7","Single Cell Type RNA - Late spermatids [nTPM]":"139.7","Single Cell Type RNA - Leydig cells [nTPM]":"22.4","Single Cell Type RNA - Macrophages [nTPM]":"31.4","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"68.4","Single Cell Type RNA - monocytes [nTPM]":"30.0","Single Cell Type RNA - Muller glia cells [nTPM]":"38.2","Single Cell Type RNA - NK-cells [nTPM]":"43.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"79.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"260.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.6","Single Cell Type RNA - Paneth cells [nTPM]":"23.7","Single Cell Type RNA - Peritubular cells [nTPM]":"15.4","Single Cell Type RNA - Plasma cells [nTPM]":"50.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"25.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"21.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"26.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"26.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.0","Single Cell Type RNA - Spermatocytes [nTPM]":"40.6","Single Cell Type RNA - Spermatogonia [nTPM]":"25.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"30.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"46.9","Single Cell Type RNA - T-cells [nTPM]":"30.8","Single Cell Type RNA - Theca cells [nTPM]":"12.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.9","Single Cell Type RNA - Urothelial cells [nTPM]":"40.6"},{"Gene":"ITGA6","Gene synonym":["CD49f"],"Ensembl":"ENSG00000091409","Gene description":"Integrin subunit alpha 6","Uniprot":["P23229"],"Chromosome":"2","Position":"172427354-172506459","Protein class":["Cancer-related genes","CD markers","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion"],"Molecular function":["Integrin","Receptor"],"Disease involvement":["Cancer-related genes","Epidermolysis bullosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"327.2","Basal keratinocytes":"244.7","Urothelial cells":"247.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"144.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"22.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"28","RNA blood lineage specific nTPM":{"granulocytes":"22.9","NK-cells":"7.1","T-cells":"12.8"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ":"326.2","HaCaT":"356.8","HBEC3-KT":"705.8","hTCEpi":"298.9","hTERT-HME1":"301.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009009","HPA012696","HPA027582"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3300000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009009":"AB_2128038","HPA012696":"AB_1851822","HPA027582":"AB_10602606"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.03e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.35e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-3"},"Tissue RNA - adipose tissue [nTPM]":"45.9","Tissue RNA - adrenal gland [nTPM]":"8.3","Tissue RNA - amygdala [nTPM]":"20.1","Tissue RNA - appendix [nTPM]":"27.8","Tissue RNA - basal ganglia [nTPM]":"16.7","Tissue RNA - bone marrow [nTPM]":"5.8","Tissue RNA - breast [nTPM]":"55.6","Tissue RNA - cerebellum [nTPM]":"16.6","Tissue RNA - cerebral cortex [nTPM]":"20.3","Tissue RNA - cervix [nTPM]":"64.3","Tissue RNA - choroid plexus [nTPM]":"42.8","Tissue RNA - colon [nTPM]":"65.4","Tissue RNA - duodenum [nTPM]":"74.2","Tissue RNA - endometrium 1 [nTPM]":"43.1","Tissue RNA - epididymis [nTPM]":"9.5","Tissue RNA - esophagus [nTPM]":"25.1","Tissue RNA - fallopian tube [nTPM]":"25.3","Tissue RNA - gallbladder [nTPM]":"37.2","Tissue RNA - heart muscle [nTPM]":"29.2","Tissue RNA - hippocampal formation [nTPM]":"17.2","Tissue RNA - hypothalamus [nTPM]":"20.9","Tissue RNA - kidney [nTPM]":"42.7","Tissue RNA - liver [nTPM]":"8.8","Tissue RNA - lung [nTPM]":"29.3","Tissue RNA - lymph node [nTPM]":"18.7","Tissue RNA - medulla oblongata [nTPM]":"20.8","Tissue RNA - midbrain [nTPM]":"18.8","Tissue RNA - ovary [nTPM]":"5.6","Tissue RNA - pancreas [nTPM]":"42.0","Tissue RNA - parathyroid gland [nTPM]":"14.0","Tissue RNA - pituitary gland [nTPM]":"6.2","Tissue RNA - placenta [nTPM]":"76.8","Tissue RNA - pons [nTPM]":"19.3","Tissue RNA - prostate [nTPM]":"24.4","Tissue RNA - rectum [nTPM]":"62.4","Tissue RNA - retina [nTPM]":"7.3","Tissue RNA - salivary gland [nTPM]":"81.0","Tissue RNA - seminal vesicle [nTPM]":"30.8","Tissue RNA - skeletal muscle [nTPM]":"27.7","Tissue RNA - skin 1 [nTPM]":"46.6","Tissue RNA - small intestine [nTPM]":"67.4","Tissue RNA - smooth muscle [nTPM]":"39.0","Tissue RNA - spinal cord [nTPM]":"20.5","Tissue RNA - spleen [nTPM]":"41.2","Tissue RNA - stomach 1 [nTPM]":"66.1","Tissue RNA - testis [nTPM]":"26.1","Tissue RNA - thalamus [nTPM]":"25.0","Tissue RNA - thymus [nTPM]":"33.9","Tissue RNA - thyroid gland [nTPM]":"21.1","Tissue RNA - tongue [nTPM]":"42.6","Tissue RNA - tonsil [nTPM]":"21.4","Tissue RNA - urinary bladder [nTPM]":"55.0","Tissue RNA - vagina [nTPM]":"26.8","Tissue RNA - white matter [nTPM]":"16.5","Cell RNA - A-431 [nTPM]":"77.5","Cell RNA - A549 [nTPM]":"64.8","Cell RNA - AF22 [nTPM]":"26.7","Cell RNA - AN3-CA [nTPM]":"49.1","Cell RNA - ASC diff [nTPM]":"1.4","Cell RNA - ASC TERT1 [nTPM]":"0.9","Cell RNA - BEWO [nTPM]":"146.3","Cell RNA - BJ [nTPM]":"326.2","Cell RNA - BJ hTERT+ [nTPM]":"34.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"32.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.0","Cell RNA - CACO-2 [nTPM]":"36.2","Cell RNA - CAPAN-2 [nTPM]":"141.3","Cell RNA - Daudi [nTPM]":"0.7","Cell RNA - EFO-21 [nTPM]":"90.9","Cell RNA - fHDF\/TERT166 [nTPM]":"86.8","Cell RNA - GAMG [nTPM]":"73.8","Cell RNA - HaCaT [nTPM]":"356.8","Cell RNA - HAP1 [nTPM]":"17.7","Cell RNA - HBEC3-KT [nTPM]":"705.8","Cell RNA - HBF TERT88 [nTPM]":"58.1","Cell RNA - HDLM-2 [nTPM]":"0.7","Cell RNA - HEK 293 [nTPM]":"16.6","Cell RNA - HEL [nTPM]":"1.9","Cell RNA - HeLa [nTPM]":"64.8","Cell RNA - Hep G2 [nTPM]":"58.7","Cell RNA - HHSteC [nTPM]":"4.8","Cell RNA - HL-60 [nTPM]":"21.4","Cell RNA - HMC-1 [nTPM]":"2.4","Cell RNA - HSkMC [nTPM]":"6.2","Cell RNA - hTCEpi [nTPM]":"298.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.0","Cell RNA - hTERT-HME1 [nTPM]":"301.4","Cell RNA - hTERT-RPE1 [nTPM]":"32.9","Cell RNA - HUVEC TERT2 [nTPM]":"209.6","Cell RNA - JURKAT [nTPM]":"40.8","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"5.5","Cell RNA - LHCN-M2 [nTPM]":"41.6","Cell RNA - MCF7 [nTPM]":"3.7","Cell RNA - MOLT-4 [nTPM]":"5.9","Cell RNA - NB-4 [nTPM]":"17.8","Cell RNA - NTERA-2 [nTPM]":"48.2","Cell RNA - OE19 [nTPM]":"214.2","Cell RNA - PC-3 [nTPM]":"54.5","Cell RNA - REH [nTPM]":"1.1","Cell RNA - RH-30 [nTPM]":"82.3","Cell RNA - RPMI-8226 [nTPM]":"1.6","Cell RNA - RPTEC TERT1 [nTPM]":"48.0","Cell RNA - RT4 [nTPM]":"106.6","Cell RNA - SCLC-21H [nTPM]":"0.8","Cell RNA - SH-SY5Y [nTPM]":"3.4","Cell RNA - SiHa [nTPM]":"61.2","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"69.7","Cell RNA - SuSa [nTPM]":"28.0","Cell RNA - T-47d [nTPM]":"13.1","Cell RNA - THP-1 [nTPM]":"1.4","Cell RNA - TIME [nTPM]":"97.9","Cell RNA - U-138 MG [nTPM]":"44.9","Cell RNA - U-2 OS [nTPM]":"41.1","Cell RNA - U-2197 [nTPM]":"84.2","Cell RNA - U-251 MG [nTPM]":"56.8","Cell RNA - U-266\/70 [nTPM]":"4.8","Cell RNA - U-266\/84 [nTPM]":"3.6","Cell RNA - U-698 [nTPM]":"1.9","Cell RNA - U-87 MG [nTPM]":"1.7","Cell RNA - U-937 [nTPM]":"7.2","Cell RNA - WM-115 [nTPM]":"185.0","Blood RNA - basophil [nTPM]":"4.4","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"22.9","Blood RNA - gdT-cell [nTPM]":"5.3","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"10.7","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"6.7","Blood RNA - memory CD8 T-cell [nTPM]":"6.4","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"12.8","Blood RNA - naive CD8 T-cell [nTPM]":"5.9","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"7.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"8.1","Blood RNA - total PBMC [nTPM]":"4.3","Brain RNA - amygdala [nTPM]":"20.1","Brain RNA - basal ganglia [nTPM]":"16.7","Brain RNA - cerebellum [nTPM]":"16.6","Brain RNA - cerebral cortex [nTPM]":"20.3","Brain RNA - hippocampal formation [nTPM]":"17.2","Brain RNA - hypothalamus [nTPM]":"20.9","Brain RNA - medulla oblongata [nTPM]":"20.8","Brain RNA - midbrain [nTPM]":"18.8","Brain RNA - pons [nTPM]":"19.3","Brain RNA - spinal cord [nTPM]":"20.5","Brain RNA - thalamus [nTPM]":"25.0","Brain RNA - white matter [nTPM]":"16.5","Single Cell Type RNA - Adipocytes [nTPM]":"327.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.5","Single Cell Type RNA - Astrocytes [nTPM]":"88.5","Single Cell Type RNA - B-cells [nTPM]":"8.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"244.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"236.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"43.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"88.8","Single Cell Type RNA - Bipolar cells [nTPM]":"1.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"55.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"72.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"32.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"10.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"56.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"103.8","Single Cell Type RNA - dendritic cells [nTPM]":"14.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"139.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"34.4","Single Cell Type RNA - Early spermatids [nTPM]":"31.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"82.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"34.8","Single Cell Type RNA - Endothelial cells [nTPM]":"196.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"57.4","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"62.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.5","Single Cell Type RNA - Fibroblasts [nTPM]":"20.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"219.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"149.3","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"103.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"21.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.5","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"128.8","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"3.2","Single Cell Type RNA - Langerhans cells [nTPM]":"20.8","Single Cell Type RNA - Late spermatids [nTPM]":"46.8","Single Cell Type RNA - Leydig cells [nTPM]":"4.1","Single Cell Type RNA - Macrophages [nTPM]":"10.0","Single Cell Type RNA - Melanocytes [nTPM]":"51.6","Single Cell Type RNA - Microglial cells [nTPM]":"119.9","Single Cell Type RNA - monocytes [nTPM]":"1.7","Single Cell Type RNA - Muller glia cells [nTPM]":"1.3","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"127.9","Single Cell Type RNA - Paneth cells [nTPM]":"104.2","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"109.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"184.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"54.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"52.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.4","Single Cell Type RNA - Spermatocytes [nTPM]":"7.7","Single Cell Type RNA - Spermatogonia [nTPM]":"20.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"141.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"84.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.3","Single Cell Type RNA - T-cells [nTPM]":"30.1","Single Cell Type RNA - Theca cells [nTPM]":"44.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"146.3","Single Cell Type RNA - Urothelial cells [nTPM]":"247.6"},{"Gene":"ITGA7","Gene synonym":[],"Ensembl":"ENSG00000135424","Gene description":"Integrin subunit alpha 7","Uniprot":["Q13683"],"Chromosome":"12","Position":"55684568-55716043","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion","Cell shape"],"Molecular function":["Integrin","Receptor"],"Disease involvement":["Congenital muscular dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"262.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Astrocytes":"87.5","Cardiomyocytes":"124.5","Sertoli cells":"164.3","Skeletal myocytes":"65.8","Smooth muscle cells":"110.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"35.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"hTERT-RPE1":"309.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008427"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1200000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear speckles","Vesicles"],"Antibody RRID":{"HPA008427":"AB_1851823"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.75e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.59e-5"},"Tissue RNA - adipose tissue [nTPM]":"133.4","Tissue RNA - adrenal gland [nTPM]":"8.2","Tissue RNA - amygdala [nTPM]":"18.5","Tissue RNA - appendix [nTPM]":"18.5","Tissue RNA - basal ganglia [nTPM]":"21.2","Tissue RNA - bone marrow [nTPM]":"1.8","Tissue RNA - breast [nTPM]":"69.0","Tissue RNA - cerebellum [nTPM]":"15.9","Tissue RNA - cerebral cortex [nTPM]":"30.2","Tissue RNA - cervix [nTPM]":"28.7","Tissue RNA - choroid plexus [nTPM]":"16.1","Tissue RNA - colon [nTPM]":"97.8","Tissue RNA - duodenum [nTPM]":"17.7","Tissue RNA - endometrium 1 [nTPM]":"45.5","Tissue RNA - epididymis [nTPM]":"12.3","Tissue RNA - esophagus [nTPM]":"23.9","Tissue RNA - fallopian tube [nTPM]":"56.1","Tissue RNA - gallbladder [nTPM]":"30.8","Tissue RNA - heart muscle [nTPM]":"157.9","Tissue RNA - hippocampal formation [nTPM]":"34.5","Tissue RNA - hypothalamus [nTPM]":"17.8","Tissue RNA - kidney [nTPM]":"11.5","Tissue RNA - liver [nTPM]":"10.2","Tissue RNA - lung [nTPM]":"15.5","Tissue RNA - lymph node [nTPM]":"6.4","Tissue RNA - medulla oblongata [nTPM]":"21.2","Tissue RNA - midbrain [nTPM]":"21.1","Tissue RNA - ovary [nTPM]":"19.1","Tissue RNA - pancreas [nTPM]":"5.1","Tissue RNA - parathyroid gland [nTPM]":"6.1","Tissue RNA - pituitary gland [nTPM]":"12.6","Tissue RNA - placenta [nTPM]":"1.9","Tissue RNA - pons [nTPM]":"20.3","Tissue RNA - prostate [nTPM]":"33.9","Tissue RNA - rectum [nTPM]":"8.9","Tissue RNA - retina [nTPM]":"2.4","Tissue RNA - salivary gland [nTPM]":"14.9","Tissue RNA - seminal vesicle [nTPM]":"37.3","Tissue RNA - skeletal muscle [nTPM]":"262.3","Tissue RNA - skin 1 [nTPM]":"16.0","Tissue RNA - small intestine [nTPM]":"27.4","Tissue RNA - smooth muscle [nTPM]":"95.2","Tissue RNA - spinal cord [nTPM]":"16.4","Tissue RNA - spleen [nTPM]":"10.2","Tissue RNA - stomach 1 [nTPM]":"35.2","Tissue RNA - testis [nTPM]":"8.9","Tissue RNA - thalamus [nTPM]":"23.8","Tissue RNA - thymus [nTPM]":"3.4","Tissue RNA - thyroid gland [nTPM]":"26.1","Tissue RNA - tongue [nTPM]":"154.1","Tissue RNA - tonsil [nTPM]":"3.3","Tissue RNA - urinary bladder [nTPM]":"46.5","Tissue RNA - vagina [nTPM]":"25.5","Tissue RNA - white matter [nTPM]":"21.0","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"4.1","Cell RNA - AF22 [nTPM]":"7.5","Cell RNA - AN3-CA [nTPM]":"12.3","Cell RNA - ASC diff [nTPM]":"66.5","Cell RNA - ASC TERT1 [nTPM]":"13.4","Cell RNA - BEWO [nTPM]":"0.7","Cell RNA - BJ [nTPM]":"5.4","Cell RNA - BJ hTERT+ [nTPM]":"8.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.8","Cell RNA - CACO-2 [nTPM]":"8.4","Cell RNA - CAPAN-2 [nTPM]":"6.5","Cell RNA - Daudi [nTPM]":"2.3","Cell RNA - EFO-21 [nTPM]":"7.4","Cell RNA - fHDF\/TERT166 [nTPM]":"3.4","Cell RNA - GAMG [nTPM]":"0.9","Cell RNA - HaCaT [nTPM]":"1.1","Cell RNA - HAP1 [nTPM]":"5.1","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"10.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"3.8","Cell RNA - HEL [nTPM]":"0.8","Cell RNA - HeLa [nTPM]":"2.8","Cell RNA - Hep G2 [nTPM]":"3.2","Cell RNA - HHSteC [nTPM]":"0.5","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"2.7","Cell RNA - HSkMC [nTPM]":"19.1","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"64.2","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"309.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"2.2","Cell RNA - K-562 [nTPM]":"0.9","Cell RNA - Karpas-707 [nTPM]":"1.6","Cell RNA - LHCN-M2 [nTPM]":"37.8","Cell RNA - MCF7 [nTPM]":"5.3","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"3.1","Cell RNA - NTERA-2 [nTPM]":"20.9","Cell RNA - OE19 [nTPM]":"1.7","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"28.7","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.9","Cell RNA - SH-SY5Y [nTPM]":"2.8","Cell RNA - SiHa [nTPM]":"0.6","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"48.0","Cell RNA - SuSa [nTPM]":"4.0","Cell RNA - T-47d [nTPM]":"0.9","Cell RNA - THP-1 [nTPM]":"13.9","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"1.3","Cell RNA - U-2 OS [nTPM]":"12.4","Cell RNA - U-2197 [nTPM]":"0.8","Cell RNA - U-251 MG [nTPM]":"8.4","Cell RNA - U-266\/70 [nTPM]":"3.2","Cell RNA - U-266\/84 [nTPM]":"2.2","Cell RNA - U-698 [nTPM]":"0.9","Cell RNA - U-87 MG [nTPM]":"57.8","Cell RNA - U-937 [nTPM]":"8.2","Cell RNA - WM-115 [nTPM]":"0.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"18.5","Brain RNA - basal ganglia [nTPM]":"21.2","Brain RNA - cerebellum [nTPM]":"15.9","Brain RNA - cerebral cortex [nTPM]":"30.2","Brain RNA - hippocampal formation [nTPM]":"34.5","Brain RNA - hypothalamus [nTPM]":"17.8","Brain RNA - medulla oblongata [nTPM]":"21.2","Brain RNA - midbrain [nTPM]":"21.1","Brain RNA - pons [nTPM]":"20.3","Brain RNA - spinal cord [nTPM]":"16.4","Brain RNA - thalamus [nTPM]":"23.8","Brain RNA - white matter [nTPM]":"21.0","Single Cell Type RNA - Adipocytes [nTPM]":"11.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"87.5","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"2.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"124.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.2","Single Cell Type RNA - Endothelial cells [nTPM]":"9.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.7","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"5.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"6.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"1.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"2.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"2.2","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"3.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"164.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"65.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"110.6","Single Cell Type RNA - Spermatocytes [nTPM]":"4.1","Single Cell Type RNA - Spermatogonia [nTPM]":"2.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.9","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"ITK","Gene synonym":["EMT","LYK","PSCTK2"],"Ensembl":"ENSG00000113263","Gene description":"IL2 inducible T cell kinase","Uniprot":["Q08881"],"Chromosome":"5","Position":"157142933-157255185","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"lymphoid tissue":"57.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"dendritic cells":"51.7","granulocytes":"31.8","NK-cells":"42.2","Plasma cells":"34.0","T-cells":"115.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"23","RNA blood cell specific nTPM":{"gdT-cell":"39.6","MAIT T-cell":"26.4","memory CD4 T-cell":"55.6","memory CD8 T-cell":"54.9","naive CD4 T-cell":"78.2","naive CD8 T-cell":"65.0","NK-cell":"29.3","T-reg":"73.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"23","RNA blood lineage specific nTPM":{"NK-cells":"29.3","T-cells":"78.2"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"JURKAT":"62.2","MOLT-4":"23.7"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043670"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA043670":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.0","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"15.9","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"3.7","Tissue RNA - breast [nTPM]":"0.9","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"1.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.4","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"1.4","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"4.2","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"1.6","Tissue RNA - lung [nTPM]":"3.1","Tissue RNA - lymph node [nTPM]":"29.3","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"1.5","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"4.0","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"10.5","Tissue RNA - stomach 1 [nTPM]":"3.1","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"57.9","Tissue RNA - thyroid gland [nTPM]":"0.5","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"24.6","Tissue RNA - urinary bladder [nTPM]":"3.9","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"3.6","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"3.9","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"4.5","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"62.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"23.7","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"2.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"39.6","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"26.4","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"55.6","Blood RNA - memory CD8 T-cell [nTPM]":"54.9","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"78.2","Blood RNA - naive CD8 T-cell [nTPM]":"65.0","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"29.3","Blood RNA - non-classical monocyte [nTPM]":"2.3","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"73.2","Blood RNA - total PBMC [nTPM]":"44.3","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"4.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"51.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"8.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"31.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"1.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"5.1","Single Cell Type RNA - Late spermatids [nTPM]":"6.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"2.9","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"2.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"42.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"34.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"115.7","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"ITM2B","Gene synonym":["BRI","BRI2","BRICD2B","E25B","E3-16"],"Ensembl":"ENSG00000136156","Gene description":"Integral membrane protein 2B","Uniprot":["Q9Y287"],"Chromosome":"13","Position":"48232612-48270357","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Amyloidosis","Deafness","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"4375.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"4375.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"731.2","RPTEC TERT1":"1718.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029292","HPA071992"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5800000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA029292":"AB_10601917","HPA071992":"AB_2686480"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.73e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Tissue RNA - adipose tissue [nTPM]":"510.2","Tissue RNA - adrenal gland [nTPM]":"367.4","Tissue RNA - amygdala [nTPM]":"286.9","Tissue RNA - appendix [nTPM]":"172.5","Tissue RNA - basal ganglia [nTPM]":"301.0","Tissue RNA - bone marrow [nTPM]":"125.6","Tissue RNA - breast [nTPM]":"323.8","Tissue RNA - cerebellum [nTPM]":"328.6","Tissue RNA - cerebral cortex [nTPM]":"489.0","Tissue RNA - cervix [nTPM]":"416.1","Tissue RNA - choroid plexus [nTPM]":"406.6","Tissue RNA - colon [nTPM]":"260.1","Tissue RNA - duodenum [nTPM]":"289.2","Tissue RNA - endometrium 1 [nTPM]":"388.8","Tissue RNA - epididymis [nTPM]":"1171.8","Tissue RNA - esophagus [nTPM]":"399.9","Tissue RNA - fallopian tube [nTPM]":"305.4","Tissue RNA - gallbladder [nTPM]":"257.5","Tissue RNA - heart muscle [nTPM]":"381.0","Tissue RNA - hippocampal formation [nTPM]":"320.1","Tissue RNA - hypothalamus [nTPM]":"339.2","Tissue RNA - kidney [nTPM]":"1306.3","Tissue RNA - liver [nTPM]":"391.2","Tissue RNA - lung [nTPM]":"376.1","Tissue RNA - lymph node [nTPM]":"236.7","Tissue RNA - medulla oblongata [nTPM]":"334.9","Tissue RNA - midbrain [nTPM]":"308.0","Tissue RNA - ovary [nTPM]":"507.2","Tissue RNA - pancreas [nTPM]":"179.6","Tissue RNA - parathyroid gland [nTPM]":"233.7","Tissue RNA - pituitary gland [nTPM]":"290.5","Tissue RNA - placenta [nTPM]":"573.8","Tissue RNA - pons [nTPM]":"304.4","Tissue RNA - prostate [nTPM]":"312.5","Tissue RNA - rectum [nTPM]":"191.4","Tissue RNA - retina [nTPM]":"174.4","Tissue RNA - salivary gland [nTPM]":"408.7","Tissue RNA - seminal vesicle [nTPM]":"386.2","Tissue RNA - skeletal muscle [nTPM]":"164.7","Tissue RNA - skin 1 [nTPM]":"399.6","Tissue RNA - small intestine [nTPM]":"287.4","Tissue RNA - smooth muscle [nTPM]":"232.5","Tissue RNA - spinal cord [nTPM]":"373.6","Tissue RNA - spleen [nTPM]":"435.2","Tissue RNA - stomach 1 [nTPM]":"312.8","Tissue RNA - testis [nTPM]":"121.4","Tissue RNA - thalamus [nTPM]":"308.8","Tissue RNA - thymus [nTPM]":"188.3","Tissue RNA - thyroid gland [nTPM]":"386.1","Tissue RNA - tongue [nTPM]":"206.2","Tissue RNA - tonsil [nTPM]":"187.4","Tissue RNA - urinary bladder [nTPM]":"305.1","Tissue RNA - vagina [nTPM]":"402.2","Tissue RNA - white matter [nTPM]":"394.8","Cell RNA - A-431 [nTPM]":"67.6","Cell RNA - A549 [nTPM]":"51.8","Cell RNA - AF22 [nTPM]":"73.1","Cell RNA - AN3-CA [nTPM]":"116.3","Cell RNA - ASC diff [nTPM]":"348.5","Cell RNA - ASC TERT1 [nTPM]":"254.5","Cell RNA - BEWO [nTPM]":"119.2","Cell RNA - BJ [nTPM]":"215.0","Cell RNA - BJ hTERT+ [nTPM]":"202.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"87.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"100.6","Cell RNA - CACO-2 [nTPM]":"29.1","Cell RNA - CAPAN-2 [nTPM]":"248.3","Cell RNA - Daudi [nTPM]":"16.6","Cell RNA - EFO-21 [nTPM]":"168.8","Cell RNA - fHDF\/TERT166 [nTPM]":"121.6","Cell RNA - GAMG [nTPM]":"48.5","Cell RNA - HaCaT [nTPM]":"214.1","Cell RNA - HAP1 [nTPM]":"61.3","Cell RNA - HBEC3-KT [nTPM]":"107.0","Cell RNA - HBF TERT88 [nTPM]":"107.4","Cell RNA - HDLM-2 [nTPM]":"69.9","Cell RNA - HEK 293 [nTPM]":"147.3","Cell RNA - HEL [nTPM]":"137.9","Cell RNA - HeLa [nTPM]":"29.0","Cell RNA - Hep G2 [nTPM]":"99.0","Cell RNA - HHSteC [nTPM]":"138.5","Cell RNA - HL-60 [nTPM]":"140.6","Cell RNA - HMC-1 [nTPM]":"731.2","Cell RNA - HSkMC [nTPM]":"113.4","Cell RNA - hTCEpi [nTPM]":"149.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"45.1","Cell RNA - hTERT-HME1 [nTPM]":"62.0","Cell RNA - hTERT-RPE1 [nTPM]":"375.7","Cell RNA - HUVEC TERT2 [nTPM]":"131.2","Cell RNA - JURKAT [nTPM]":"78.3","Cell RNA - K-562 [nTPM]":"24.5","Cell RNA - Karpas-707 [nTPM]":"90.9","Cell RNA - LHCN-M2 [nTPM]":"174.8","Cell RNA - MCF7 [nTPM]":"29.6","Cell RNA - MOLT-4 [nTPM]":"200.4","Cell RNA - NB-4 [nTPM]":"310.1","Cell RNA - NTERA-2 [nTPM]":"266.0","Cell RNA - OE19 [nTPM]":"116.5","Cell RNA - PC-3 [nTPM]":"103.6","Cell RNA - REH [nTPM]":"100.1","Cell RNA - RH-30 [nTPM]":"100.5","Cell RNA - RPMI-8226 [nTPM]":"73.6","Cell RNA - RPTEC TERT1 [nTPM]":"1718.9","Cell RNA - RT4 [nTPM]":"268.6","Cell RNA - SCLC-21H [nTPM]":"26.2","Cell RNA - SH-SY5Y [nTPM]":"119.5","Cell RNA - SiHa [nTPM]":"154.5","Cell RNA - SK-BR-3 [nTPM]":"110.2","Cell RNA - SK-MEL-30 [nTPM]":"111.0","Cell RNA - SuSa [nTPM]":"306.0","Cell RNA - T-47d [nTPM]":"74.0","Cell RNA - THP-1 [nTPM]":"119.4","Cell RNA - TIME [nTPM]":"180.5","Cell RNA - U-138 MG [nTPM]":"62.9","Cell RNA - U-2 OS [nTPM]":"73.8","Cell RNA - U-2197 [nTPM]":"95.7","Cell RNA - U-251 MG [nTPM]":"85.4","Cell RNA - U-266\/70 [nTPM]":"72.9","Cell RNA - U-266\/84 [nTPM]":"59.6","Cell RNA - U-698 [nTPM]":"2.5","Cell RNA - U-87 MG [nTPM]":"78.0","Cell RNA - U-937 [nTPM]":"75.3","Cell RNA - WM-115 [nTPM]":"155.3","Blood RNA - basophil [nTPM]":"3091.4","Blood RNA - classical monocyte [nTPM]":"864.5","Blood RNA - eosinophil [nTPM]":"2737.9","Blood RNA - gdT-cell [nTPM]":"387.4","Blood RNA - intermediate monocyte [nTPM]":"661.3","Blood RNA - MAIT T-cell [nTPM]":"512.5","Blood RNA - memory B-cell [nTPM]":"235.3","Blood RNA - memory CD4 T-cell [nTPM]":"523.1","Blood RNA - memory CD8 T-cell [nTPM]":"476.4","Blood RNA - myeloid DC [nTPM]":"428.9","Blood RNA - naive B-cell [nTPM]":"245.3","Blood RNA - naive CD4 T-cell [nTPM]":"551.3","Blood RNA - naive CD8 T-cell [nTPM]":"466.8","Blood RNA - neutrophil [nTPM]":"4375.2","Blood RNA - NK-cell [nTPM]":"356.5","Blood RNA - non-classical monocyte [nTPM]":"692.7","Blood RNA - plasmacytoid DC [nTPM]":"196.2","Blood RNA - T-reg [nTPM]":"563.4","Blood RNA - total PBMC [nTPM]":"1723.5","Brain RNA - amygdala [nTPM]":"286.9","Brain RNA - basal ganglia [nTPM]":"301.0","Brain RNA - cerebellum [nTPM]":"328.6","Brain RNA - cerebral cortex [nTPM]":"489.0","Brain RNA - hippocampal formation [nTPM]":"320.1","Brain RNA - hypothalamus [nTPM]":"339.2","Brain RNA - medulla oblongata [nTPM]":"334.9","Brain RNA - midbrain [nTPM]":"308.0","Brain RNA - pons [nTPM]":"304.4","Brain RNA - spinal cord [nTPM]":"373.6","Brain RNA - thalamus [nTPM]":"308.8","Brain RNA - white matter [nTPM]":"394.8","Single Cell Type RNA - Adipocytes [nTPM]":"1380.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"695.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"300.4","Single Cell Type RNA - Astrocytes [nTPM]":"174.6","Single Cell Type RNA - B-cells [nTPM]":"408.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"862.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1661.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2606.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1006.2","Single Cell Type RNA - Bipolar cells [nTPM]":"653.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"460.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"573.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"384.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"722.0","Single Cell Type RNA - Club cells [nTPM]":"1121.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"1991.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"187.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1164.3","Single Cell Type RNA - dendritic cells [nTPM]":"448.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"754.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"545.9","Single Cell Type RNA - Ductal cells [nTPM]":"910.2","Single Cell Type RNA - Early spermatids [nTPM]":"23.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"751.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"802.2","Single Cell Type RNA - Endothelial cells [nTPM]":"1166.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"283.3","Single Cell Type RNA - Erythroid cells [nTPM]":"307.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"114.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"682.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2362.8","Single Cell Type RNA - Fibroblasts [nTPM]":"1334.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"302.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1177.2","Single Cell Type RNA - granulocytes [nTPM]":"578.0","Single Cell Type RNA - Granulosa cells [nTPM]":"421.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1319.7","Single Cell Type RNA - Hepatocytes [nTPM]":"557.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"2117.8","Single Cell Type RNA - Horizontal cells [nTPM]":"353.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"142.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"503.2","Single Cell Type RNA - Ionocytes [nTPM]":"1129.1","Single Cell Type RNA - Kupffer cells [nTPM]":"1569.8","Single Cell Type RNA - Langerhans cells [nTPM]":"900.6","Single Cell Type RNA - Late spermatids [nTPM]":"76.7","Single Cell Type RNA - Leydig cells [nTPM]":"1867.0","Single Cell Type RNA - Macrophages [nTPM]":"1381.5","Single Cell Type RNA - Melanocytes [nTPM]":"681.3","Single Cell Type RNA - Microglial cells [nTPM]":"252.0","Single Cell Type RNA - monocytes [nTPM]":"1415.7","Single Cell Type RNA - Muller glia cells [nTPM]":"1634.9","Single Cell Type RNA - NK-cells [nTPM]":"425.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"174.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"237.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"515.7","Single Cell Type RNA - Paneth cells [nTPM]":"788.3","Single Cell Type RNA - Peritubular cells [nTPM]":"2011.6","Single Cell Type RNA - Plasma cells [nTPM]":"445.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"922.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1259.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2748.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"795.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"219.4","Single Cell Type RNA - Sertoli cells [nTPM]":"1222.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"602.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1022.9","Single Cell Type RNA - Spermatocytes [nTPM]":"143.6","Single Cell Type RNA - Spermatogonia [nTPM]":"256.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1384.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1149.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1471.5","Single Cell Type RNA - T-cells [nTPM]":"723.2","Single Cell Type RNA - Theca cells [nTPM]":"665.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"440.9","Single Cell Type RNA - Urothelial cells [nTPM]":"1613.4"},{"Gene":"ITPA","Gene synonym":["C20orf37","dJ794I6.3","HLC14-06-P"],"Ensembl":"ENSG00000125877","Gene description":"Inosine triphosphatase","Uniprot":["Q9BY32"],"Chromosome":"20","Position":"3208868-3223870","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Nucleotide metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022824","HPA073963"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"120000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA022824":"AB_1851960","HPA073963":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.54e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Tissue RNA - adipose tissue [nTPM]":"26.2","Tissue RNA - adrenal gland [nTPM]":"37.1","Tissue RNA - amygdala [nTPM]":"16.7","Tissue RNA - appendix [nTPM]":"21.2","Tissue RNA - basal ganglia [nTPM]":"17.5","Tissue RNA - bone marrow [nTPM]":"26.4","Tissue RNA - breast [nTPM]":"25.0","Tissue RNA - cerebellum [nTPM]":"16.9","Tissue RNA - cerebral cortex [nTPM]":"20.0","Tissue RNA - cervix [nTPM]":"24.8","Tissue RNA - choroid plexus [nTPM]":"18.2","Tissue RNA - colon [nTPM]":"25.3","Tissue RNA - duodenum [nTPM]":"27.0","Tissue RNA - endometrium 1 [nTPM]":"24.0","Tissue RNA - epididymis [nTPM]":"13.0","Tissue RNA - esophagus [nTPM]":"43.9","Tissue RNA - fallopian tube [nTPM]":"29.9","Tissue RNA - gallbladder [nTPM]":"16.7","Tissue RNA - heart muscle [nTPM]":"20.8","Tissue RNA - hippocampal formation [nTPM]":"18.2","Tissue RNA - hypothalamus [nTPM]":"16.8","Tissue RNA - kidney [nTPM]":"34.2","Tissue RNA - liver [nTPM]":"28.2","Tissue RNA - lung [nTPM]":"22.4","Tissue RNA - lymph node [nTPM]":"27.6","Tissue RNA - medulla oblongata [nTPM]":"17.0","Tissue RNA - midbrain [nTPM]":"16.5","Tissue RNA - ovary [nTPM]":"21.2","Tissue RNA - pancreas [nTPM]":"21.9","Tissue RNA - parathyroid gland [nTPM]":"24.2","Tissue RNA - pituitary gland [nTPM]":"13.0","Tissue RNA - placenta [nTPM]":"19.8","Tissue RNA - pons [nTPM]":"17.0","Tissue RNA - prostate [nTPM]":"20.3","Tissue RNA - rectum [nTPM]":"19.2","Tissue RNA - retina [nTPM]":"6.9","Tissue RNA - salivary gland [nTPM]":"26.4","Tissue RNA - seminal vesicle [nTPM]":"16.1","Tissue RNA - skeletal muscle [nTPM]":"26.5","Tissue RNA - skin 1 [nTPM]":"33.6","Tissue RNA - small intestine [nTPM]":"23.2","Tissue RNA - smooth muscle [nTPM]":"18.5","Tissue RNA - spinal cord [nTPM]":"17.3","Tissue RNA - spleen [nTPM]":"27.0","Tissue RNA - stomach 1 [nTPM]":"27.1","Tissue RNA - testis [nTPM]":"12.3","Tissue RNA - thalamus [nTPM]":"18.0","Tissue RNA - thymus [nTPM]":"24.8","Tissue RNA - thyroid gland [nTPM]":"33.5","Tissue RNA - tongue [nTPM]":"15.1","Tissue RNA - tonsil [nTPM]":"21.4","Tissue RNA - urinary bladder [nTPM]":"24.1","Tissue RNA - vagina [nTPM]":"25.7","Tissue RNA - white matter [nTPM]":"18.5","Cell RNA - A-431 [nTPM]":"118.2","Cell RNA - A549 [nTPM]":"91.1","Cell RNA - AF22 [nTPM]":"44.0","Cell RNA - AN3-CA [nTPM]":"49.1","Cell RNA - ASC diff [nTPM]":"29.7","Cell RNA - ASC TERT1 [nTPM]":"42.7","Cell RNA - BEWO [nTPM]":"30.9","Cell RNA - BJ [nTPM]":"50.9","Cell RNA - BJ hTERT+ [nTPM]":"72.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"65.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"58.8","Cell RNA - CACO-2 [nTPM]":"75.0","Cell RNA - CAPAN-2 [nTPM]":"106.6","Cell RNA - Daudi [nTPM]":"52.5","Cell RNA - EFO-21 [nTPM]":"46.9","Cell RNA - fHDF\/TERT166 [nTPM]":"48.7","Cell RNA - GAMG [nTPM]":"65.7","Cell RNA - HaCaT [nTPM]":"101.9","Cell RNA - HAP1 [nTPM]":"62.3","Cell RNA - HBEC3-KT [nTPM]":"79.8","Cell RNA - HBF TERT88 [nTPM]":"46.6","Cell RNA - HDLM-2 [nTPM]":"32.9","Cell RNA - HEK 293 [nTPM]":"91.6","Cell RNA - HEL [nTPM]":"123.9","Cell RNA - HeLa [nTPM]":"39.1","Cell RNA - Hep G2 [nTPM]":"117.6","Cell RNA - HHSteC [nTPM]":"55.5","Cell RNA - HL-60 [nTPM]":"54.5","Cell RNA - HMC-1 [nTPM]":"41.4","Cell RNA - HSkMC [nTPM]":"41.5","Cell RNA - hTCEpi [nTPM]":"60.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"64.4","Cell RNA - hTERT-HME1 [nTPM]":"40.9","Cell RNA - hTERT-RPE1 [nTPM]":"28.6","Cell RNA - HUVEC TERT2 [nTPM]":"52.5","Cell RNA - JURKAT [nTPM]":"39.5","Cell RNA - K-562 [nTPM]":"88.7","Cell RNA - Karpas-707 [nTPM]":"34.2","Cell RNA - LHCN-M2 [nTPM]":"62.6","Cell RNA - MCF7 [nTPM]":"55.2","Cell RNA - MOLT-4 [nTPM]":"66.0","Cell RNA - NB-4 [nTPM]":"156.5","Cell RNA - NTERA-2 [nTPM]":"77.2","Cell RNA - OE19 [nTPM]":"132.1","Cell RNA - PC-3 [nTPM]":"89.6","Cell RNA - REH [nTPM]":"61.4","Cell RNA - RH-30 [nTPM]":"60.7","Cell RNA - RPMI-8226 [nTPM]":"135.0","Cell RNA - RPTEC TERT1 [nTPM]":"96.7","Cell RNA - RT4 [nTPM]":"39.2","Cell RNA - SCLC-21H [nTPM]":"67.4","Cell RNA - SH-SY5Y [nTPM]":"80.9","Cell RNA - SiHa [nTPM]":"41.4","Cell RNA - SK-BR-3 [nTPM]":"154.0","Cell RNA - SK-MEL-30 [nTPM]":"106.3","Cell RNA - SuSa [nTPM]":"19.3","Cell RNA - T-47d [nTPM]":"60.1","Cell RNA - THP-1 [nTPM]":"94.2","Cell RNA - TIME [nTPM]":"37.9","Cell RNA - U-138 MG [nTPM]":"76.5","Cell RNA - U-2 OS [nTPM]":"42.4","Cell RNA - U-2197 [nTPM]":"51.7","Cell RNA - U-251 MG [nTPM]":"116.0","Cell RNA - U-266\/70 [nTPM]":"52.0","Cell RNA - U-266\/84 [nTPM]":"68.4","Cell RNA - U-698 [nTPM]":"94.2","Cell RNA - U-87 MG [nTPM]":"32.9","Cell RNA - U-937 [nTPM]":"102.8","Cell RNA - WM-115 [nTPM]":"83.0","Blood RNA - basophil [nTPM]":"32.8","Blood RNA - classical monocyte [nTPM]":"61.5","Blood RNA - eosinophil [nTPM]":"22.9","Blood RNA - gdT-cell [nTPM]":"47.7","Blood RNA - intermediate monocyte [nTPM]":"78.2","Blood RNA - MAIT T-cell [nTPM]":"41.7","Blood RNA - memory B-cell [nTPM]":"48.9","Blood RNA - memory CD4 T-cell [nTPM]":"43.6","Blood RNA - memory CD8 T-cell [nTPM]":"49.0","Blood RNA - myeloid DC [nTPM]":"74.5","Blood RNA - naive B-cell [nTPM]":"50.2","Blood RNA - naive CD4 T-cell [nTPM]":"32.4","Blood RNA - naive CD8 T-cell [nTPM]":"39.5","Blood RNA - neutrophil [nTPM]":"3.4","Blood RNA - NK-cell [nTPM]":"64.5","Blood RNA - non-classical monocyte [nTPM]":"56.9","Blood RNA - plasmacytoid DC [nTPM]":"70.7","Blood RNA - T-reg [nTPM]":"61.0","Blood RNA - total PBMC [nTPM]":"48.0","Brain RNA - amygdala [nTPM]":"16.7","Brain RNA - basal ganglia [nTPM]":"17.5","Brain RNA - cerebellum [nTPM]":"16.9","Brain RNA - cerebral cortex [nTPM]":"20.0","Brain RNA - hippocampal formation [nTPM]":"18.2","Brain RNA - hypothalamus [nTPM]":"16.8","Brain RNA - medulla oblongata [nTPM]":"17.0","Brain RNA - midbrain [nTPM]":"16.5","Brain RNA - pons [nTPM]":"17.0","Brain RNA - spinal cord [nTPM]":"17.3","Brain RNA - thalamus [nTPM]":"18.0","Brain RNA - white matter [nTPM]":"18.5","Single Cell Type RNA - Adipocytes [nTPM]":"29.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"47.0","Single Cell Type RNA - Astrocytes [nTPM]":"15.3","Single Cell Type RNA - B-cells [nTPM]":"38.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"40.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"50.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"93.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"56.9","Single Cell Type RNA - Bipolar cells [nTPM]":"20.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"48.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"58.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"34.3","Single Cell Type RNA - Club cells [nTPM]":"59.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"74.4","Single Cell Type RNA - dendritic cells [nTPM]":"45.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"37.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"58.7","Single Cell Type RNA - Ductal cells [nTPM]":"104.2","Single Cell Type RNA - Early spermatids [nTPM]":"2.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"51.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"64.4","Single Cell Type RNA - Endothelial cells [nTPM]":"29.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"27.5","Single Cell Type RNA - Erythroid cells [nTPM]":"24.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"105.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"128.2","Single Cell Type RNA - Fibroblasts [nTPM]":"41.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"48.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"60.9","Single Cell Type RNA - granulocytes [nTPM]":"42.5","Single Cell Type RNA - Granulosa cells [nTPM]":"49.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"29.3","Single Cell Type RNA - Hepatocytes [nTPM]":"32.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"116.6","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"53.1","Single Cell Type RNA - Ionocytes [nTPM]":"54.9","Single Cell Type RNA - Kupffer cells [nTPM]":"42.4","Single Cell Type RNA - Langerhans cells [nTPM]":"54.0","Single Cell Type RNA - Late spermatids [nTPM]":"3.7","Single Cell Type RNA - Leydig cells [nTPM]":"31.1","Single Cell Type RNA - Macrophages [nTPM]":"49.0","Single Cell Type RNA - Melanocytes [nTPM]":"40.9","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"90.3","Single Cell Type RNA - Muller glia cells [nTPM]":"21.0","Single Cell Type RNA - NK-cells [nTPM]":"41.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"102.2","Single Cell Type RNA - Paneth cells [nTPM]":"59.9","Single Cell Type RNA - Peritubular cells [nTPM]":"22.2","Single Cell Type RNA - Plasma cells [nTPM]":"34.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"53.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"51.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"94.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"37.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.5","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"35.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"45.0","Single Cell Type RNA - Spermatocytes [nTPM]":"16.8","Single Cell Type RNA - Spermatogonia [nTPM]":"17.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"58.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"49.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"56.2","Single Cell Type RNA - T-cells [nTPM]":"47.2","Single Cell Type RNA - Theca cells [nTPM]":"53.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"79.9","Single Cell Type RNA - Urothelial cells [nTPM]":"66.0"},{"Gene":"ITPR1","Gene synonym":["ACV","Insp3r1","IP3R1","PPP1R94","SCA15","SCA16","SCA29"],"Ensembl":"ENSG00000150995","Gene description":"Inositol 1,4,5-trisphosphate receptor type 1","Uniprot":["Q14643"],"Chromosome":"3","Position":"4493345-4847840","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","Mental retardation","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"290.2","Inhibitory neurons":"183.1","Microglial cells":"84.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"49.9"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"13.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"76.4","HEL":"41.1","HeLa":"74.9","HMC-1":"40.0","U-87 MG":"56.7"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebellum":"697.2"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"208.8"},"Antibody":["HPA014765","HPA016487"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA014765":"AB_1851843","HPA016487":"AB_1851842"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.43e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.6","Tissue RNA - adrenal gland [nTPM]":"12.0","Tissue RNA - amygdala [nTPM]":"1.8","Tissue RNA - appendix [nTPM]":"11.8","Tissue RNA - basal ganglia [nTPM]":"12.0","Tissue RNA - bone marrow [nTPM]":"7.2","Tissue RNA - breast [nTPM]":"17.3","Tissue RNA - cerebellum [nTPM]":"49.9","Tissue RNA - cerebral cortex [nTPM]":"20.1","Tissue RNA - cervix [nTPM]":"11.5","Tissue RNA - choroid plexus [nTPM]":"15.6","Tissue RNA - colon [nTPM]":"19.5","Tissue RNA - duodenum [nTPM]":"4.5","Tissue RNA - endometrium 1 [nTPM]":"36.5","Tissue RNA - epididymis [nTPM]":"10.0","Tissue RNA - esophagus [nTPM]":"10.6","Tissue RNA - fallopian tube [nTPM]":"27.1","Tissue RNA - gallbladder [nTPM]":"14.1","Tissue RNA - heart muscle [nTPM]":"10.1","Tissue RNA - hippocampal formation [nTPM]":"5.9","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"13.9","Tissue RNA - liver [nTPM]":"3.9","Tissue RNA - lung [nTPM]":"13.7","Tissue RNA - lymph node [nTPM]":"11.2","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.5","Tissue RNA - ovary [nTPM]":"25.3","Tissue RNA - pancreas [nTPM]":"6.7","Tissue RNA - parathyroid gland [nTPM]":"45.3","Tissue RNA - pituitary gland [nTPM]":"16.0","Tissue RNA - placenta [nTPM]":"8.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"21.7","Tissue RNA - rectum [nTPM]":"6.3","Tissue RNA - retina [nTPM]":"3.9","Tissue RNA - salivary gland [nTPM]":"16.1","Tissue RNA - seminal vesicle [nTPM]":"27.9","Tissue RNA - skeletal muscle [nTPM]":"3.0","Tissue RNA - skin 1 [nTPM]":"5.0","Tissue RNA - small intestine [nTPM]":"11.5","Tissue RNA - smooth muscle [nTPM]":"24.5","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"9.2","Tissue RNA - stomach 1 [nTPM]":"11.1","Tissue RNA - testis [nTPM]":"4.5","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"10.3","Tissue RNA - thyroid gland [nTPM]":"31.7","Tissue RNA - tongue [nTPM]":"5.3","Tissue RNA - tonsil [nTPM]":"10.5","Tissue RNA - urinary bladder [nTPM]":"27.9","Tissue RNA - vagina [nTPM]":"11.8","Tissue RNA - white matter [nTPM]":"6.1","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"4.1","Cell RNA - AF22 [nTPM]":"1.0","Cell RNA - AN3-CA [nTPM]":"3.0","Cell RNA - ASC diff [nTPM]":"27.7","Cell RNA - ASC TERT1 [nTPM]":"1.9","Cell RNA - BEWO [nTPM]":"11.8","Cell RNA - BJ [nTPM]":"0.9","Cell RNA - BJ hTERT+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.8","Cell RNA - CACO-2 [nTPM]":"1.3","Cell RNA - CAPAN-2 [nTPM]":"1.2","Cell RNA - Daudi [nTPM]":"14.5","Cell RNA - EFO-21 [nTPM]":"0.6","Cell RNA - fHDF\/TERT166 [nTPM]":"1.9","Cell RNA - GAMG [nTPM]":"6.5","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"2.2","Cell RNA - HBEC3-KT [nTPM]":"2.6","Cell RNA - HBF TERT88 [nTPM]":"2.1","Cell RNA - HDLM-2 [nTPM]":"76.4","Cell RNA - HEK 293 [nTPM]":"3.2","Cell RNA - HEL [nTPM]":"41.1","Cell RNA - HeLa [nTPM]":"74.9","Cell RNA - Hep G2 [nTPM]":"3.5","Cell RNA - HHSteC [nTPM]":"27.4","Cell RNA - HL-60 [nTPM]":"17.7","Cell RNA - HMC-1 [nTPM]":"40.0","Cell RNA - HSkMC [nTPM]":"9.2","Cell RNA - hTCEpi [nTPM]":"4.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.8","Cell RNA - hTERT-HME1 [nTPM]":"1.1","Cell RNA - hTERT-RPE1 [nTPM]":"7.6","Cell RNA - HUVEC TERT2 [nTPM]":"7.2","Cell RNA - JURKAT [nTPM]":"8.4","Cell RNA - K-562 [nTPM]":"7.9","Cell RNA - Karpas-707 [nTPM]":"13.9","Cell RNA - LHCN-M2 [nTPM]":"3.7","Cell RNA - MCF7 [nTPM]":"1.8","Cell RNA - MOLT-4 [nTPM]":"7.2","Cell RNA - NB-4 [nTPM]":"3.0","Cell RNA - NTERA-2 [nTPM]":"2.1","Cell RNA - OE19 [nTPM]":"0.5","Cell RNA - PC-3 [nTPM]":"9.7","Cell RNA - REH [nTPM]":"4.2","Cell RNA - RH-30 [nTPM]":"1.0","Cell RNA - RPMI-8226 [nTPM]":"1.1","Cell RNA - RPTEC TERT1 [nTPM]":"1.7","Cell RNA - RT4 [nTPM]":"5.5","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"19.5","Cell RNA - SiHa [nTPM]":"5.4","Cell RNA - SK-BR-3 [nTPM]":"4.3","Cell RNA - SK-MEL-30 [nTPM]":"4.3","Cell RNA - SuSa [nTPM]":"0.9","Cell RNA - T-47d [nTPM]":"2.6","Cell RNA - THP-1 [nTPM]":"20.6","Cell RNA - TIME [nTPM]":"13.5","Cell RNA - U-138 MG [nTPM]":"1.8","Cell RNA - U-2 OS [nTPM]":"4.3","Cell RNA - U-2197 [nTPM]":"3.7","Cell RNA - U-251 MG [nTPM]":"2.3","Cell RNA - U-266\/70 [nTPM]":"17.7","Cell RNA - U-266\/84 [nTPM]":"12.0","Cell RNA - U-698 [nTPM]":"9.6","Cell RNA - U-87 MG [nTPM]":"56.7","Cell RNA - U-937 [nTPM]":"17.0","Cell RNA - WM-115 [nTPM]":"2.7","Blood RNA - basophil [nTPM]":"5.8","Blood RNA - classical monocyte [nTPM]":"2.0","Blood RNA - eosinophil [nTPM]":"1.5","Blood RNA - gdT-cell [nTPM]":"2.3","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"1.7","Blood RNA - memory B-cell [nTPM]":"6.7","Blood RNA - memory CD4 T-cell [nTPM]":"1.6","Blood RNA - memory CD8 T-cell [nTPM]":"1.6","Blood RNA - myeloid DC [nTPM]":"2.2","Blood RNA - naive B-cell [nTPM]":"13.4","Blood RNA - naive CD4 T-cell [nTPM]":"2.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.6","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"4.7","Blood RNA - T-reg [nTPM]":"1.4","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"1.8","Brain RNA - basal ganglia [nTPM]":"12.0","Brain RNA - cerebellum [nTPM]":"49.9","Brain RNA - cerebral cortex [nTPM]":"20.1","Brain RNA - hippocampal formation [nTPM]":"5.9","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.5","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"6.1","Single Cell Type RNA - Adipocytes [nTPM]":"30.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.4","Single Cell Type RNA - Astrocytes [nTPM]":"24.8","Single Cell Type RNA - B-cells [nTPM]":"49.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"4.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"40.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"29.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"11.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"17.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.4","Single Cell Type RNA - Early spermatids [nTPM]":"5.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.9","Single Cell Type RNA - Endothelial cells [nTPM]":"31.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.5","Single Cell Type RNA - Erythroid cells [nTPM]":"8.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"290.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"21.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.7","Single Cell Type RNA - granulocytes [nTPM]":"26.5","Single Cell Type RNA - Granulosa cells [nTPM]":"22.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"36.0","Single Cell Type RNA - Hepatocytes [nTPM]":"2.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.7","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"183.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.3","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"12.9","Single Cell Type RNA - Langerhans cells [nTPM]":"17.4","Single Cell Type RNA - Late spermatids [nTPM]":"7.9","Single Cell Type RNA - Leydig cells [nTPM]":"30.1","Single Cell Type RNA - Macrophages [nTPM]":"23.9","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"84.3","Single Cell Type RNA - monocytes [nTPM]":"14.2","Single Cell Type RNA - Muller glia cells [nTPM]":"4.3","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"25.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.5","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"52.6","Single Cell Type RNA - Plasma cells [nTPM]":"8.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.5","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"28.2","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"2.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"25.7","Single Cell Type RNA - Theca cells [nTPM]":"22.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.8","Single Cell Type RNA - Urothelial cells [nTPM]":"3.3"},{"Gene":"IVD","Gene synonym":["ACAD2"],"Ensembl":"ENSG00000128928","Gene description":"Isovaleryl-CoA dehydrogenase","Uniprot":["P26440"],"Chromosome":"15","Position":"40405485-40435947","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"135.0","Theca cells":"105.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041391","HPA044250"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA041391":"AB_2677449","HPA044250":"AB_2678875"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.95e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.91e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-3"},"Tissue RNA - adipose tissue [nTPM]":"25.8","Tissue RNA - adrenal gland [nTPM]":"80.5","Tissue RNA - amygdala [nTPM]":"35.1","Tissue RNA - appendix [nTPM]":"14.5","Tissue RNA - basal ganglia [nTPM]":"40.8","Tissue RNA - bone marrow [nTPM]":"15.9","Tissue RNA - breast [nTPM]":"45.3","Tissue RNA - cerebellum [nTPM]":"35.6","Tissue RNA - cerebral cortex [nTPM]":"40.8","Tissue RNA - cervix [nTPM]":"29.4","Tissue RNA - choroid plexus [nTPM]":"39.5","Tissue RNA - colon [nTPM]":"31.6","Tissue RNA - duodenum [nTPM]":"24.3","Tissue RNA - endometrium 1 [nTPM]":"26.4","Tissue RNA - epididymis [nTPM]":"29.0","Tissue RNA - esophagus [nTPM]":"16.0","Tissue RNA - fallopian tube [nTPM]":"35.0","Tissue RNA - gallbladder [nTPM]":"21.5","Tissue RNA - heart muscle [nTPM]":"61.7","Tissue RNA - hippocampal formation [nTPM]":"34.0","Tissue RNA - hypothalamus [nTPM]":"41.5","Tissue RNA - kidney [nTPM]":"59.1","Tissue RNA - liver [nTPM]":"145.4","Tissue RNA - lung [nTPM]":"24.3","Tissue RNA - lymph node [nTPM]":"19.6","Tissue RNA - medulla oblongata [nTPM]":"40.2","Tissue RNA - midbrain [nTPM]":"38.8","Tissue RNA - ovary [nTPM]":"43.3","Tissue RNA - pancreas [nTPM]":"27.4","Tissue RNA - parathyroid gland [nTPM]":"39.2","Tissue RNA - pituitary gland [nTPM]":"58.3","Tissue RNA - placenta [nTPM]":"15.3","Tissue RNA - pons [nTPM]":"37.5","Tissue RNA - prostate [nTPM]":"42.1","Tissue RNA - rectum [nTPM]":"27.2","Tissue RNA - retina [nTPM]":"13.0","Tissue RNA - salivary gland [nTPM]":"31.8","Tissue RNA - seminal vesicle [nTPM]":"36.8","Tissue RNA - skeletal muscle [nTPM]":"55.7","Tissue RNA - skin 1 [nTPM]":"8.6","Tissue RNA - small intestine [nTPM]":"26.8","Tissue RNA - smooth muscle [nTPM]":"23.8","Tissue RNA - spinal cord [nTPM]":"37.9","Tissue RNA - spleen [nTPM]":"27.9","Tissue RNA - stomach 1 [nTPM]":"46.7","Tissue RNA - testis [nTPM]":"25.0","Tissue RNA - thalamus [nTPM]":"44.5","Tissue RNA - thymus [nTPM]":"16.8","Tissue RNA - thyroid gland [nTPM]":"119.2","Tissue RNA - tongue [nTPM]":"55.4","Tissue RNA - tonsil [nTPM]":"19.5","Tissue RNA - urinary bladder [nTPM]":"31.1","Tissue RNA - vagina [nTPM]":"20.8","Tissue RNA - white matter [nTPM]":"45.3","Cell RNA - A-431 [nTPM]":"20.9","Cell RNA - A549 [nTPM]":"11.9","Cell RNA - AF22 [nTPM]":"22.9","Cell RNA - AN3-CA [nTPM]":"38.9","Cell RNA - ASC diff [nTPM]":"35.9","Cell RNA - ASC TERT1 [nTPM]":"32.9","Cell RNA - BEWO [nTPM]":"1.0","Cell RNA - BJ [nTPM]":"27.6","Cell RNA - BJ hTERT+ [nTPM]":"32.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"39.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.0","Cell RNA - CACO-2 [nTPM]":"36.5","Cell RNA - CAPAN-2 [nTPM]":"16.0","Cell RNA - Daudi [nTPM]":"0.8","Cell RNA - EFO-21 [nTPM]":"57.7","Cell RNA - fHDF\/TERT166 [nTPM]":"43.4","Cell RNA - GAMG [nTPM]":"32.6","Cell RNA - HaCaT [nTPM]":"20.8","Cell RNA - HAP1 [nTPM]":"45.9","Cell RNA - HBEC3-KT [nTPM]":"46.6","Cell RNA - HBF TERT88 [nTPM]":"30.1","Cell RNA - HDLM-2 [nTPM]":"36.4","Cell RNA - HEK 293 [nTPM]":"34.0","Cell RNA - HEL [nTPM]":"52.1","Cell RNA - HeLa [nTPM]":"36.2","Cell RNA - Hep G2 [nTPM]":"38.9","Cell RNA - HHSteC [nTPM]":"64.6","Cell RNA - HL-60 [nTPM]":"22.0","Cell RNA - HMC-1 [nTPM]":"48.5","Cell RNA - HSkMC [nTPM]":"45.3","Cell RNA - hTCEpi [nTPM]":"18.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"23.5","Cell RNA - hTERT-HME1 [nTPM]":"55.3","Cell RNA - hTERT-RPE1 [nTPM]":"46.3","Cell RNA - HUVEC TERT2 [nTPM]":"38.8","Cell RNA - JURKAT [nTPM]":"60.4","Cell RNA - K-562 [nTPM]":"2.5","Cell RNA - Karpas-707 [nTPM]":"2.4","Cell RNA - LHCN-M2 [nTPM]":"42.1","Cell RNA - MCF7 [nTPM]":"27.1","Cell RNA - MOLT-4 [nTPM]":"27.3","Cell RNA - NB-4 [nTPM]":"38.9","Cell RNA - NTERA-2 [nTPM]":"17.8","Cell RNA - OE19 [nTPM]":"1.3","Cell RNA - PC-3 [nTPM]":"33.0","Cell RNA - REH [nTPM]":"41.2","Cell RNA - RH-30 [nTPM]":"32.6","Cell RNA - RPMI-8226 [nTPM]":"27.9","Cell RNA - RPTEC TERT1 [nTPM]":"45.2","Cell RNA - RT4 [nTPM]":"51.6","Cell RNA - SCLC-21H [nTPM]":"37.3","Cell RNA - SH-SY5Y [nTPM]":"21.5","Cell RNA - SiHa [nTPM]":"38.2","Cell RNA - SK-BR-3 [nTPM]":"83.4","Cell RNA - SK-MEL-30 [nTPM]":"18.7","Cell RNA - SuSa [nTPM]":"21.5","Cell RNA - T-47d [nTPM]":"69.0","Cell RNA - THP-1 [nTPM]":"117.6","Cell RNA - TIME [nTPM]":"27.6","Cell RNA - U-138 MG [nTPM]":"29.9","Cell RNA - U-2 OS [nTPM]":"20.2","Cell RNA - U-2197 [nTPM]":"23.6","Cell RNA - U-251 MG [nTPM]":"24.9","Cell RNA - U-266\/70 [nTPM]":"54.5","Cell RNA - U-266\/84 [nTPM]":"38.5","Cell RNA - U-698 [nTPM]":"1.0","Cell RNA - U-87 MG [nTPM]":"30.9","Cell RNA - U-937 [nTPM]":"22.8","Cell RNA - WM-115 [nTPM]":"28.4","Blood RNA - basophil [nTPM]":"17.0","Blood RNA - classical monocyte [nTPM]":"24.8","Blood RNA - eosinophil [nTPM]":"36.7","Blood RNA - gdT-cell [nTPM]":"33.3","Blood RNA - intermediate monocyte [nTPM]":"36.1","Blood RNA - MAIT T-cell [nTPM]":"31.0","Blood RNA - memory B-cell [nTPM]":"27.5","Blood RNA - memory CD4 T-cell [nTPM]":"18.5","Blood RNA - memory CD8 T-cell [nTPM]":"26.6","Blood RNA - myeloid DC [nTPM]":"58.8","Blood RNA - naive B-cell [nTPM]":"27.6","Blood RNA - naive CD4 T-cell [nTPM]":"18.5","Blood RNA - naive CD8 T-cell [nTPM]":"26.7","Blood RNA - neutrophil [nTPM]":"2.3","Blood RNA - NK-cell [nTPM]":"39.4","Blood RNA - non-classical monocyte [nTPM]":"73.1","Blood RNA - plasmacytoid DC [nTPM]":"89.2","Blood RNA - T-reg [nTPM]":"26.9","Blood RNA - total PBMC [nTPM]":"24.3","Brain RNA - amygdala [nTPM]":"35.1","Brain RNA - basal ganglia [nTPM]":"40.8","Brain RNA - cerebellum [nTPM]":"35.6","Brain RNA - cerebral cortex [nTPM]":"40.8","Brain RNA - hippocampal formation [nTPM]":"34.0","Brain RNA - hypothalamus [nTPM]":"41.5","Brain RNA - medulla oblongata [nTPM]":"40.2","Brain RNA - midbrain [nTPM]":"38.8","Brain RNA - pons [nTPM]":"37.5","Brain RNA - spinal cord [nTPM]":"37.9","Brain RNA - thalamus [nTPM]":"44.5","Brain RNA - white matter [nTPM]":"45.3","Single Cell Type RNA - Adipocytes [nTPM]":"13.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"54.5","Single Cell Type RNA - Astrocytes [nTPM]":"27.4","Single Cell Type RNA - B-cells [nTPM]":"19.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Bipolar cells [nTPM]":"26.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"27.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"22.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"88.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"45.8","Single Cell Type RNA - Club cells [nTPM]":"29.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.3","Single Cell Type RNA - dendritic cells [nTPM]":"34.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"95.9","Single Cell Type RNA - Ductal cells [nTPM]":"19.7","Single Cell Type RNA - Early spermatids [nTPM]":"5.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"21.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"31.0","Single Cell Type RNA - Endothelial cells [nTPM]":"18.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.7","Single Cell Type RNA - Erythroid cells [nTPM]":"21.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.3","Single Cell Type RNA - Fibroblasts [nTPM]":"20.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"29.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.9","Single Cell Type RNA - granulocytes [nTPM]":"34.7","Single Cell Type RNA - Granulosa cells [nTPM]":"46.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.4","Single Cell Type RNA - Hepatocytes [nTPM]":"135.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.1","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"16.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.4","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"18.3","Single Cell Type RNA - Langerhans cells [nTPM]":"6.2","Single Cell Type RNA - Late spermatids [nTPM]":"7.4","Single Cell Type RNA - Leydig cells [nTPM]":"20.5","Single Cell Type RNA - Macrophages [nTPM]":"18.6","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"28.8","Single Cell Type RNA - Muller glia cells [nTPM]":"26.0","Single Cell Type RNA - NK-cells [nTPM]":"26.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"25.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.8","Single Cell Type RNA - Paneth cells [nTPM]":"9.4","Single Cell Type RNA - Peritubular cells [nTPM]":"24.8","Single Cell Type RNA - Plasma cells [nTPM]":"10.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"97.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.9","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"25.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.2","Single Cell Type RNA - Spermatocytes [nTPM]":"16.1","Single Cell Type RNA - Spermatogonia [nTPM]":"3.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.9","Single Cell Type RNA - T-cells [nTPM]":"18.0","Single Cell Type RNA - Theca cells [nTPM]":"105.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"35.4","Single Cell Type RNA - Urothelial cells [nTPM]":"11.9"},{"Gene":"IYD","Gene synonym":["C6orf71","DEHAL1","dJ422F24.1"],"Ensembl":"ENSG00000009765","Gene description":"Iodotyrosine deiodinase","Uniprot":["Q6PHW0"],"Chromosome":"6","Position":"150368892-150405969","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Congenital hypothyroidism","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"thyroid gland":"472.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"23.7","Hepatocytes":"25.1","Intestinal goblet cells":"21.8","Paneth cells":"22.5","Proximal enterocytes":"89.1","Proximal tubular cells":"35.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"20","RNA cancer specific FPKM":{"thyroid cancer":"80.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"CACO-2":"1.3","OE19":"3.0","SK-BR-3":"3.2"},"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"13","RNA mouse brain regional specific nTPM":{"hippocampal formation":"7.4","thalamus":"2.4"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059627"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA059627":"AB_2684086"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.22e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"6.4","Tissue RNA - duodenum [nTPM]":"18.1","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"8.9","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"26.6","Tissue RNA - liver [nTPM]":"33.6","Tissue RNA - lung [nTPM]":"0.7","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.6","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"6.5","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"19.6","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"2.0","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.5","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"472.7","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"1.3","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"3.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"3.2","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"1.6","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"1.9","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"1.3","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.6","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.5","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"8.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.2","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"25.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"22.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"89.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"35.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"JPH2","Gene synonym":["JP-2"],"Ensembl":"ENSG00000149596","Gene description":"Junctophilin 2","Uniprot":["Q9BR39"],"Chromosome":"20","Position":"44106590-44187188","Protein class":["Disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Developmental protein","DNA-binding","Repressor"],"Disease involvement":["Cardiomyopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"85.2","skeletal muscle":"120.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cardiomyocytes":"64.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"15.3","EFO-21":"15.0","fHDF\/TERT166":"19.1","HeLa":"12.6","SiHa":"12.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052646"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052646":"AB_2681899"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.0","Tissue RNA - adrenal gland [nTPM]":"1.9","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"4.5","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"5.7","Tissue RNA - cerebellum [nTPM]":"0.4","Tissue RNA - cerebral cortex [nTPM]":"0.7","Tissue RNA - cervix [nTPM]":"15.1","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"63.3","Tissue RNA - duodenum [nTPM]":"2.1","Tissue RNA - endometrium 1 [nTPM]":"51.6","Tissue RNA - epididymis [nTPM]":"2.9","Tissue RNA - esophagus [nTPM]":"11.9","Tissue RNA - fallopian tube [nTPM]":"30.0","Tissue RNA - gallbladder [nTPM]":"3.5","Tissue RNA - heart muscle [nTPM]":"85.2","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"0.5","Tissue RNA - kidney [nTPM]":"1.4","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"5.2","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"1.1","Tissue RNA - midbrain [nTPM]":"1.1","Tissue RNA - ovary [nTPM]":"3.9","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"1.2","Tissue RNA - placenta [nTPM]":"3.8","Tissue RNA - pons [nTPM]":"0.8","Tissue RNA - prostate [nTPM]":"23.8","Tissue RNA - rectum [nTPM]":"4.5","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"5.8","Tissue RNA - seminal vesicle [nTPM]":"22.1","Tissue RNA - skeletal muscle [nTPM]":"120.4","Tissue RNA - skin 1 [nTPM]":"3.8","Tissue RNA - small intestine [nTPM]":"11.8","Tissue RNA - smooth muscle [nTPM]":"27.5","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"1.3","Tissue RNA - stomach 1 [nTPM]":"16.0","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"1.5","Tissue RNA - tongue [nTPM]":"48.3","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"40.5","Tissue RNA - vagina [nTPM]":"10.6","Tissue RNA - white matter [nTPM]":"0.7","Cell RNA - A-431 [nTPM]":"7.5","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.3","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"1.5","Cell RNA - BJ [nTPM]":"2.2","Cell RNA - BJ hTERT+ [nTPM]":"4.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.3","Cell RNA - CACO-2 [nTPM]":"15.3","Cell RNA - CAPAN-2 [nTPM]":"5.9","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"15.0","Cell RNA - fHDF\/TERT166 [nTPM]":"19.1","Cell RNA - GAMG [nTPM]":"6.1","Cell RNA - HaCaT [nTPM]":"10.5","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.5","Cell RNA - HBF TERT88 [nTPM]":"2.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"12.6","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.7","Cell RNA - hTCEpi [nTPM]":"1.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.7","Cell RNA - hTERT-HME1 [nTPM]":"3.7","Cell RNA - hTERT-RPE1 [nTPM]":"3.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"7.3","Cell RNA - MCF7 [nTPM]":"4.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.9","Cell RNA - REH [nTPM]":"1.7","Cell RNA - RH-30 [nTPM]":"3.4","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.4","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"12.9","Cell RNA - SK-BR-3 [nTPM]":"3.1","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"8.6","Cell RNA - T-47d [nTPM]":"10.8","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"2.4","Cell RNA - U-2 OS [nTPM]":"2.7","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"4.7","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"3.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"0.4","Brain RNA - cerebral cortex [nTPM]":"0.7","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"0.5","Brain RNA - medulla oblongata [nTPM]":"1.1","Brain RNA - midbrain [nTPM]":"1.1","Brain RNA - pons [nTPM]":"0.8","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"0.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"64.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"2.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"1.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"JPH3","Gene synonym":["CAGL237","HDL2","JP-3","JP3","TNRC22"],"Ensembl":"ENSG00000154118","Gene description":"Junctophilin 3","Uniprot":["Q8WXH2"],"Chromosome":"16","Position":"87601835-87698156","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"59.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"24.4","Cone photoreceptor cells":"22.9","Early spermatids":"41.1","Excitatory neurons":"33.2","Horizontal cells":"50.5","Inhibitory neurons":"28.7","Late spermatids":"14.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.7"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"amygdala":"17.1","basal ganglia":"24.6","cerebral cortex":"59.1","hippocampal formation":"42.7","white matter":"20.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"6.5","NTERA-2":"5.7","SH-SY5Y":"7.2","SiHa":"5.0","U-2 OS":"22.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA076304"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 9: U-2 OS - Unknown function","Single cell expression cluster":"Cluster 62: Horizontal cells - Visual perception","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA076304":"AB_2686793"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"1.3","Tissue RNA - amygdala [nTPM]":"17.1","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"24.6","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"1.1","Tissue RNA - cerebral cortex [nTPM]":"59.1","Tissue RNA - cervix [nTPM]":"0.7","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.1","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.6","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"42.7","Tissue RNA - hypothalamus [nTPM]":"5.6","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"6.4","Tissue RNA - midbrain [nTPM]":"5.8","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"14.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"1.1","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"1.8","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"1.4","Tissue RNA - thalamus [nTPM]":"1.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"20.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"1.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"3.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.9","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"1.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.9","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"6.5","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"5.7","Cell RNA - OE19 [nTPM]":"1.8","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"7.2","Cell RNA - SiHa [nTPM]":"5.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"22.5","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"17.1","Brain RNA - basal ganglia [nTPM]":"24.6","Brain RNA - cerebellum [nTPM]":"1.1","Brain RNA - cerebral cortex [nTPM]":"59.1","Brain RNA - hippocampal formation [nTPM]":"42.7","Brain RNA - hypothalamus [nTPM]":"5.6","Brain RNA - medulla oblongata [nTPM]":"6.4","Brain RNA - midbrain [nTPM]":"5.8","Brain RNA - pons [nTPM]":"1.1","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"1.1","Brain RNA - white matter [nTPM]":"20.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.3","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"24.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"41.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"33.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"50.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"28.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"14.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"3.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"KARS1","Gene synonym":["DFNB89","KARS","KARS2"],"Ensembl":"ENSG00000065427","Gene description":"Lysyl-tRNA synthetase 1","Uniprot":["Q15046"],"Chromosome":"16","Position":"75627474-75648643","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Host-virus interaction","Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase","Transferase"],"Disease involvement":["Charcot-Marie-Tooth disease","Deafness","Disease variant","Neurodegeneration","Neuropathy","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Cardiomyocytes":"90.7","Cytotrophoblasts":"122.7","Extravillous trophoblasts":"143.3","Hofbauer cells":"89.5","Syncytiotrophoblasts":"110.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041345","HPA041550"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"82000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA041345":"AB_10795589","HPA041550":"AB_10794520"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.84e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Tissue RNA - adipose tissue [nTPM]":"68.5","Tissue RNA - adrenal gland [nTPM]":"49.6","Tissue RNA - amygdala [nTPM]":"45.5","Tissue RNA - appendix [nTPM]":"71.6","Tissue RNA - basal ganglia [nTPM]":"47.3","Tissue RNA - bone marrow [nTPM]":"86.1","Tissue RNA - breast [nTPM]":"83.0","Tissue RNA - cerebellum [nTPM]":"46.9","Tissue RNA - cerebral cortex [nTPM]":"63.2","Tissue RNA - cervix [nTPM]":"60.3","Tissue RNA - choroid plexus [nTPM]":"50.6","Tissue RNA - colon [nTPM]":"75.8","Tissue RNA - duodenum [nTPM]":"62.4","Tissue RNA - endometrium 1 [nTPM]":"53.9","Tissue RNA - epididymis [nTPM]":"75.1","Tissue RNA - esophagus [nTPM]":"72.5","Tissue RNA - fallopian tube [nTPM]":"69.5","Tissue RNA - gallbladder [nTPM]":"50.4","Tissue RNA - heart muscle [nTPM]":"96.0","Tissue RNA - hippocampal formation [nTPM]":"45.6","Tissue RNA - hypothalamus [nTPM]":"48.3","Tissue RNA - kidney [nTPM]":"72.2","Tissue RNA - liver [nTPM]":"76.8","Tissue RNA - lung [nTPM]":"53.1","Tissue RNA - lymph node [nTPM]":"88.3","Tissue RNA - medulla oblongata [nTPM]":"46.9","Tissue RNA - midbrain [nTPM]":"47.5","Tissue RNA - ovary [nTPM]":"74.9","Tissue RNA - pancreas [nTPM]":"86.5","Tissue RNA - parathyroid gland [nTPM]":"76.7","Tissue RNA - pituitary gland [nTPM]":"51.5","Tissue RNA - placenta [nTPM]":"62.2","Tissue RNA - pons [nTPM]":"46.8","Tissue RNA - prostate [nTPM]":"55.2","Tissue RNA - rectum [nTPM]":"85.6","Tissue RNA - retina [nTPM]":"69.6","Tissue RNA - salivary gland [nTPM]":"79.6","Tissue RNA - seminal vesicle [nTPM]":"60.6","Tissue RNA - skeletal muscle [nTPM]":"213.4","Tissue RNA - skin 1 [nTPM]":"67.3","Tissue RNA - small intestine [nTPM]":"62.6","Tissue RNA - smooth muscle [nTPM]":"69.6","Tissue RNA - spinal cord [nTPM]":"46.8","Tissue RNA - spleen [nTPM]":"57.6","Tissue RNA - stomach 1 [nTPM]":"66.2","Tissue RNA - testis [nTPM]":"98.9","Tissue RNA - thalamus [nTPM]":"47.4","Tissue RNA - thymus [nTPM]":"96.6","Tissue RNA - thyroid gland [nTPM]":"65.3","Tissue RNA - tongue [nTPM]":"186.8","Tissue RNA - tonsil [nTPM]":"107.8","Tissue RNA - urinary bladder [nTPM]":"92.1","Tissue RNA - vagina [nTPM]":"55.0","Tissue RNA - white matter [nTPM]":"48.1","Cell RNA - A-431 [nTPM]":"164.2","Cell RNA - A549 [nTPM]":"187.0","Cell RNA - AF22 [nTPM]":"133.5","Cell RNA - AN3-CA [nTPM]":"185.4","Cell RNA - ASC diff [nTPM]":"140.1","Cell RNA - ASC TERT1 [nTPM]":"140.3","Cell RNA - BEWO [nTPM]":"262.4","Cell RNA - BJ [nTPM]":"135.0","Cell RNA - BJ hTERT+ [nTPM]":"164.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"290.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"217.0","Cell RNA - CACO-2 [nTPM]":"332.8","Cell RNA - CAPAN-2 [nTPM]":"209.0","Cell RNA - Daudi [nTPM]":"292.4","Cell RNA - EFO-21 [nTPM]":"145.4","Cell RNA - fHDF\/TERT166 [nTPM]":"180.8","Cell RNA - GAMG [nTPM]":"138.4","Cell RNA - HaCaT [nTPM]":"229.4","Cell RNA - HAP1 [nTPM]":"272.0","Cell RNA - HBEC3-KT [nTPM]":"246.7","Cell RNA - HBF TERT88 [nTPM]":"314.4","Cell RNA - HDLM-2 [nTPM]":"86.0","Cell RNA - HEK 293 [nTPM]":"139.8","Cell RNA - HEL [nTPM]":"161.4","Cell RNA - HeLa [nTPM]":"153.1","Cell RNA - Hep G2 [nTPM]":"348.5","Cell RNA - HHSteC [nTPM]":"255.8","Cell RNA - HL-60 [nTPM]":"245.5","Cell RNA - HMC-1 [nTPM]":"174.1","Cell RNA - HSkMC [nTPM]":"166.4","Cell RNA - hTCEpi [nTPM]":"173.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"257.4","Cell RNA - hTERT-HME1 [nTPM]":"414.6","Cell RNA - hTERT-RPE1 [nTPM]":"147.7","Cell RNA - HUVEC TERT2 [nTPM]":"240.0","Cell RNA - JURKAT [nTPM]":"253.5","Cell RNA - K-562 [nTPM]":"273.4","Cell RNA - Karpas-707 [nTPM]":"68.5","Cell RNA - LHCN-M2 [nTPM]":"222.5","Cell RNA - MCF7 [nTPM]":"378.0","Cell RNA - MOLT-4 [nTPM]":"254.1","Cell RNA - NB-4 [nTPM]":"262.2","Cell RNA - NTERA-2 [nTPM]":"284.3","Cell RNA - OE19 [nTPM]":"238.4","Cell RNA - PC-3 [nTPM]":"135.9","Cell RNA - REH [nTPM]":"329.2","Cell RNA - RH-30 [nTPM]":"120.0","Cell RNA - RPMI-8226 [nTPM]":"358.4","Cell RNA - RPTEC TERT1 [nTPM]":"235.4","Cell RNA - RT4 [nTPM]":"136.3","Cell RNA - SCLC-21H [nTPM]":"200.2","Cell RNA - SH-SY5Y [nTPM]":"162.9","Cell RNA - SiHa [nTPM]":"339.5","Cell RNA - SK-BR-3 [nTPM]":"122.8","Cell RNA - SK-MEL-30 [nTPM]":"152.2","Cell RNA - SuSa [nTPM]":"144.8","Cell RNA - T-47d [nTPM]":"166.1","Cell RNA - THP-1 [nTPM]":"229.2","Cell RNA - TIME [nTPM]":"133.8","Cell RNA - U-138 MG [nTPM]":"159.8","Cell RNA - U-2 OS [nTPM]":"164.9","Cell RNA - U-2197 [nTPM]":"123.6","Cell RNA - U-251 MG [nTPM]":"196.7","Cell RNA - U-266\/70 [nTPM]":"145.1","Cell RNA - U-266\/84 [nTPM]":"178.6","Cell RNA - U-698 [nTPM]":"696.6","Cell RNA - U-87 MG [nTPM]":"139.5","Cell RNA - U-937 [nTPM]":"206.5","Cell RNA - WM-115 [nTPM]":"199.7","Blood RNA - basophil [nTPM]":"88.6","Blood RNA - classical monocyte [nTPM]":"112.7","Blood RNA - eosinophil [nTPM]":"130.0","Blood RNA - gdT-cell [nTPM]":"110.7","Blood RNA - intermediate monocyte [nTPM]":"155.7","Blood RNA - MAIT T-cell [nTPM]":"202.6","Blood RNA - memory B-cell [nTPM]":"109.5","Blood RNA - memory CD4 T-cell [nTPM]":"137.1","Blood RNA - memory CD8 T-cell [nTPM]":"132.0","Blood RNA - myeloid DC [nTPM]":"135.7","Blood RNA - naive B-cell [nTPM]":"91.6","Blood RNA - naive CD4 T-cell [nTPM]":"126.6","Blood RNA - naive CD8 T-cell [nTPM]":"117.1","Blood RNA - neutrophil [nTPM]":"24.9","Blood RNA - NK-cell [nTPM]":"127.6","Blood RNA - non-classical monocyte [nTPM]":"163.1","Blood RNA - plasmacytoid DC [nTPM]":"85.7","Blood RNA - T-reg [nTPM]":"155.5","Blood RNA - total PBMC [nTPM]":"160.5","Brain RNA - amygdala [nTPM]":"45.5","Brain RNA - basal ganglia [nTPM]":"47.3","Brain RNA - cerebellum [nTPM]":"46.9","Brain RNA - cerebral cortex [nTPM]":"63.2","Brain RNA - hippocampal formation [nTPM]":"45.6","Brain RNA - hypothalamus [nTPM]":"48.3","Brain RNA - medulla oblongata [nTPM]":"46.9","Brain RNA - midbrain [nTPM]":"47.5","Brain RNA - pons [nTPM]":"46.8","Brain RNA - spinal cord [nTPM]":"46.8","Brain RNA - thalamus [nTPM]":"47.4","Brain RNA - white matter [nTPM]":"48.1","Single Cell Type RNA - Adipocytes [nTPM]":"14.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"3.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"90.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"122.7","Single Cell Type RNA - dendritic cells [nTPM]":"10.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"8.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"143.3","Single Cell Type RNA - Fibroblasts [nTPM]":"14.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"89.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"2.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"3.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"110.0","Single Cell Type RNA - T-cells [nTPM]":"2.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"KAT2B","Gene synonym":["GCN5","GCN5L","P\/CAF","PCAF"],"Ensembl":"ENSG00000114166","Gene description":"Lysine acetyltransferase 2B","Uniprot":["Q92831"],"Chromosome":"3","Position":"20040446-20154404","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Biological rhythms","Cell cycle","Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Activator","Acyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"165.2","Oligodendrocyte precursor cells":"418.2","Oligodendrocytes":"175.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002470","CAB004526","HPA055839","HPA073897"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB004526":"AB_2128417","HPA002470":null,"HPA055839":"AB_2682938","HPA073897":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Tissue RNA - adipose tissue [nTPM]":"17.9","Tissue RNA - adrenal gland [nTPM]":"9.9","Tissue RNA - amygdala [nTPM]":"38.7","Tissue RNA - appendix [nTPM]":"15.4","Tissue RNA - basal ganglia [nTPM]":"46.5","Tissue RNA - bone marrow [nTPM]":"48.0","Tissue RNA - breast [nTPM]":"10.3","Tissue RNA - cerebellum [nTPM]":"39.1","Tissue RNA - cerebral cortex [nTPM]":"40.3","Tissue RNA - cervix [nTPM]":"14.9","Tissue RNA - choroid plexus [nTPM]":"33.8","Tissue RNA - colon [nTPM]":"13.8","Tissue RNA - duodenum [nTPM]":"17.7","Tissue RNA - endometrium 1 [nTPM]":"12.3","Tissue RNA - epididymis [nTPM]":"8.1","Tissue RNA - esophagus [nTPM]":"27.4","Tissue RNA - fallopian tube [nTPM]":"11.7","Tissue RNA - gallbladder [nTPM]":"12.6","Tissue RNA - heart muscle [nTPM]":"35.9","Tissue RNA - hippocampal formation [nTPM]":"34.4","Tissue RNA - hypothalamus [nTPM]":"42.2","Tissue RNA - kidney [nTPM]":"16.6","Tissue RNA - liver [nTPM]":"39.3","Tissue RNA - lung [nTPM]":"16.2","Tissue RNA - lymph node [nTPM]":"22.4","Tissue RNA - medulla oblongata [nTPM]":"41.7","Tissue RNA - midbrain [nTPM]":"44.9","Tissue RNA - ovary [nTPM]":"27.7","Tissue RNA - pancreas [nTPM]":"18.7","Tissue RNA - parathyroid gland [nTPM]":"51.0","Tissue RNA - pituitary gland [nTPM]":"10.2","Tissue RNA - placenta [nTPM]":"13.7","Tissue RNA - pons [nTPM]":"43.0","Tissue RNA - prostate [nTPM]":"14.5","Tissue RNA - rectum [nTPM]":"12.5","Tissue RNA - retina [nTPM]":"33.9","Tissue RNA - salivary gland [nTPM]":"37.6","Tissue RNA - seminal vesicle [nTPM]":"13.0","Tissue RNA - skeletal muscle [nTPM]":"60.2","Tissue RNA - skin 1 [nTPM]":"14.3","Tissue RNA - small intestine [nTPM]":"21.5","Tissue RNA - smooth muscle [nTPM]":"13.6","Tissue RNA - spinal cord [nTPM]":"37.1","Tissue RNA - spleen [nTPM]":"19.8","Tissue RNA - stomach 1 [nTPM]":"13.9","Tissue RNA - testis [nTPM]":"2.7","Tissue RNA - thalamus [nTPM]":"42.2","Tissue RNA - thymus [nTPM]":"23.6","Tissue RNA - thyroid gland [nTPM]":"14.4","Tissue RNA - tongue [nTPM]":"56.1","Tissue RNA - tonsil [nTPM]":"20.1","Tissue RNA - urinary bladder [nTPM]":"11.9","Tissue RNA - vagina [nTPM]":"15.1","Tissue RNA - white matter [nTPM]":"45.1","Cell RNA - A-431 [nTPM]":"2.7","Cell RNA - A549 [nTPM]":"6.9","Cell RNA - AF22 [nTPM]":"3.8","Cell RNA - AN3-CA [nTPM]":"6.2","Cell RNA - ASC diff [nTPM]":"15.1","Cell RNA - ASC TERT1 [nTPM]":"14.2","Cell RNA - BEWO [nTPM]":"8.8","Cell RNA - BJ [nTPM]":"8.8","Cell RNA - BJ hTERT+ [nTPM]":"13.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.3","Cell RNA - CACO-2 [nTPM]":"2.1","Cell RNA - CAPAN-2 [nTPM]":"4.5","Cell RNA - Daudi [nTPM]":"24.0","Cell RNA - EFO-21 [nTPM]":"3.6","Cell RNA - fHDF\/TERT166 [nTPM]":"16.7","Cell RNA - GAMG [nTPM]":"11.5","Cell RNA - HaCaT [nTPM]":"2.0","Cell RNA - HAP1 [nTPM]":"9.4","Cell RNA - HBEC3-KT [nTPM]":"2.8","Cell RNA - HBF TERT88 [nTPM]":"7.6","Cell RNA - HDLM-2 [nTPM]":"21.8","Cell RNA - HEK 293 [nTPM]":"9.0","Cell RNA - HEL [nTPM]":"21.0","Cell RNA - HeLa [nTPM]":"10.7","Cell RNA - Hep G2 [nTPM]":"0.7","Cell RNA - HHSteC [nTPM]":"7.1","Cell RNA - HL-60 [nTPM]":"3.2","Cell RNA - HMC-1 [nTPM]":"26.2","Cell RNA - HSkMC [nTPM]":"6.1","Cell RNA - hTCEpi [nTPM]":"5.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.9","Cell RNA - hTERT-HME1 [nTPM]":"5.1","Cell RNA - hTERT-RPE1 [nTPM]":"16.0","Cell RNA - HUVEC TERT2 [nTPM]":"8.8","Cell RNA - JURKAT [nTPM]":"5.8","Cell RNA - K-562 [nTPM]":"13.7","Cell RNA - Karpas-707 [nTPM]":"32.9","Cell RNA - LHCN-M2 [nTPM]":"13.0","Cell RNA - MCF7 [nTPM]":"3.3","Cell RNA - MOLT-4 [nTPM]":"7.0","Cell RNA - NB-4 [nTPM]":"6.4","Cell RNA - NTERA-2 [nTPM]":"1.6","Cell RNA - OE19 [nTPM]":"6.7","Cell RNA - PC-3 [nTPM]":"6.8","Cell RNA - REH [nTPM]":"9.1","Cell RNA - RH-30 [nTPM]":"7.1","Cell RNA - RPMI-8226 [nTPM]":"5.1","Cell RNA - RPTEC TERT1 [nTPM]":"12.4","Cell RNA - RT4 [nTPM]":"14.2","Cell RNA - SCLC-21H [nTPM]":"1.9","Cell RNA - SH-SY5Y [nTPM]":"4.1","Cell RNA - SiHa [nTPM]":"4.9","Cell RNA - SK-BR-3 [nTPM]":"7.9","Cell RNA - SK-MEL-30 [nTPM]":"30.5","Cell RNA - SuSa [nTPM]":"5.9","Cell RNA - T-47d [nTPM]":"8.2","Cell RNA - THP-1 [nTPM]":"14.2","Cell RNA - TIME [nTPM]":"8.5","Cell RNA - U-138 MG [nTPM]":"15.3","Cell RNA - U-2 OS [nTPM]":"6.1","Cell RNA - U-2197 [nTPM]":"5.8","Cell RNA - U-251 MG [nTPM]":"10.1","Cell RNA - U-266\/70 [nTPM]":"12.3","Cell RNA - U-266\/84 [nTPM]":"27.6","Cell RNA - U-698 [nTPM]":"5.7","Cell RNA - U-87 MG [nTPM]":"13.9","Cell RNA - U-937 [nTPM]":"13.8","Cell RNA - WM-115 [nTPM]":"33.0","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"1.3","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"1.5","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"0.8","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.8","Blood RNA - neutrophil [nTPM]":"2.4","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"2.2","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"38.7","Brain RNA - basal ganglia [nTPM]":"46.5","Brain RNA - cerebellum [nTPM]":"39.1","Brain RNA - cerebral cortex [nTPM]":"40.3","Brain RNA - hippocampal formation [nTPM]":"34.4","Brain RNA - hypothalamus [nTPM]":"42.2","Brain RNA - medulla oblongata [nTPM]":"41.7","Brain RNA - midbrain [nTPM]":"44.9","Brain RNA - pons [nTPM]":"43.0","Brain RNA - spinal cord [nTPM]":"37.1","Brain RNA - thalamus [nTPM]":"42.2","Brain RNA - white matter [nTPM]":"45.1","Single Cell Type RNA - Adipocytes [nTPM]":"15.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.8","Single Cell Type RNA - Astrocytes [nTPM]":"165.2","Single Cell Type RNA - B-cells [nTPM]":"11.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"14.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"64.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"10.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.3","Single Cell Type RNA - dendritic cells [nTPM]":"19.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"3.8","Single Cell Type RNA - Early spermatids [nTPM]":"3.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.7","Single Cell Type RNA - Endothelial cells [nTPM]":"14.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.5","Single Cell Type RNA - Erythroid cells [nTPM]":"52.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.1","Single Cell Type RNA - Fibroblasts [nTPM]":"11.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.1","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"12.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.7","Single Cell Type RNA - Hepatocytes [nTPM]":"33.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.7","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"32.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.3","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"22.8","Single Cell Type RNA - Langerhans cells [nTPM]":"23.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.8","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"16.0","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"52.5","Single Cell Type RNA - monocytes [nTPM]":"11.1","Single Cell Type RNA - Muller glia cells [nTPM]":"14.8","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"418.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"175.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.3","Single Cell Type RNA - Paneth cells [nTPM]":"2.4","Single Cell Type RNA - Peritubular cells [nTPM]":"5.3","Single Cell Type RNA - Plasma cells [nTPM]":"19.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"25.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"1.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.9","Single Cell Type RNA - T-cells [nTPM]":"23.5","Single Cell Type RNA - Theca cells [nTPM]":"2.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.8","Single Cell Type RNA - Urothelial cells [nTPM]":"8.0"},{"Gene":"KAT6A","Gene synonym":["MOZ","MYST3","RUNXBP2","ZC2HC6A","ZNF220"],"Ensembl":"ENSG00000083168","Gene description":"Lysine acetyltransferase 6A","Uniprot":["Q92794"],"Chromosome":"8","Position":"41929479-42051994","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","Acyltransferase","Chromatin regulator","Repressor","Transferase"],"Disease involvement":["Cancer-related genes","Mental retardation","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017023","HPA063266","HPA065052"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Nuclear speckles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":["Nucleoli","Cytosol"],"Antibody RRID":{"CAB017023":null,"HPA063266":"AB_2684973","HPA065052":"AB_2685414"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Tissue RNA - adipose tissue [nTPM]":"14.4","Tissue RNA - adrenal gland [nTPM]":"7.1","Tissue RNA - amygdala [nTPM]":"8.6","Tissue RNA - appendix [nTPM]":"15.4","Tissue RNA - basal ganglia [nTPM]":"12.7","Tissue RNA - bone marrow [nTPM]":"38.2","Tissue RNA - breast [nTPM]":"12.3","Tissue RNA - cerebellum [nTPM]":"20.1","Tissue RNA - cerebral cortex [nTPM]":"10.5","Tissue RNA - cervix [nTPM]":"13.7","Tissue RNA - choroid plexus [nTPM]":"9.7","Tissue RNA - colon [nTPM]":"10.2","Tissue RNA - duodenum [nTPM]":"9.6","Tissue RNA - endometrium 1 [nTPM]":"15.6","Tissue RNA - epididymis [nTPM]":"8.6","Tissue RNA - esophagus [nTPM]":"13.4","Tissue RNA - fallopian tube [nTPM]":"12.0","Tissue RNA - gallbladder [nTPM]":"11.2","Tissue RNA - heart muscle [nTPM]":"9.1","Tissue RNA - hippocampal formation [nTPM]":"9.1","Tissue RNA - hypothalamus [nTPM]":"12.8","Tissue RNA - kidney [nTPM]":"9.1","Tissue RNA - liver [nTPM]":"10.0","Tissue RNA - lung [nTPM]":"16.7","Tissue RNA - lymph node [nTPM]":"16.8","Tissue RNA - medulla oblongata [nTPM]":"12.7","Tissue RNA - midbrain [nTPM]":"12.4","Tissue RNA - ovary [nTPM]":"21.5","Tissue RNA - pancreas [nTPM]":"11.7","Tissue RNA - parathyroid gland [nTPM]":"18.0","Tissue RNA - pituitary gland [nTPM]":"6.7","Tissue RNA - placenta [nTPM]":"14.9","Tissue RNA - pons [nTPM]":"12.9","Tissue RNA - prostate [nTPM]":"11.0","Tissue RNA - rectum [nTPM]":"10.6","Tissue RNA - retina [nTPM]":"18.1","Tissue RNA - salivary gland [nTPM]":"9.6","Tissue RNA - seminal vesicle [nTPM]":"9.7","Tissue RNA - skeletal muscle [nTPM]":"13.1","Tissue RNA - skin 1 [nTPM]":"16.6","Tissue RNA - small intestine [nTPM]":"12.1","Tissue RNA - smooth muscle [nTPM]":"13.5","Tissue RNA - spinal cord [nTPM]":"8.2","Tissue RNA - spleen [nTPM]":"15.7","Tissue RNA - stomach 1 [nTPM]":"11.3","Tissue RNA - testis [nTPM]":"11.4","Tissue RNA - thalamus [nTPM]":"10.1","Tissue RNA - thymus [nTPM]":"27.0","Tissue RNA - thyroid gland [nTPM]":"14.2","Tissue RNA - tongue [nTPM]":"16.0","Tissue RNA - tonsil [nTPM]":"17.2","Tissue RNA - urinary bladder [nTPM]":"12.0","Tissue RNA - vagina [nTPM]":"10.7","Tissue RNA - white matter [nTPM]":"16.7","Cell RNA - A-431 [nTPM]":"19.6","Cell RNA - A549 [nTPM]":"23.2","Cell RNA - AF22 [nTPM]":"34.8","Cell RNA - AN3-CA [nTPM]":"21.8","Cell RNA - ASC diff [nTPM]":"17.8","Cell RNA - ASC TERT1 [nTPM]":"20.3","Cell RNA - BEWO [nTPM]":"9.8","Cell RNA - BJ [nTPM]":"15.4","Cell RNA - BJ hTERT+ [nTPM]":"20.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.2","Cell RNA - CACO-2 [nTPM]":"16.3","Cell RNA - CAPAN-2 [nTPM]":"11.5","Cell RNA - Daudi [nTPM]":"33.4","Cell RNA - EFO-21 [nTPM]":"13.4","Cell RNA - fHDF\/TERT166 [nTPM]":"19.0","Cell RNA - GAMG [nTPM]":"19.5","Cell RNA - HaCaT [nTPM]":"17.3","Cell RNA - HAP1 [nTPM]":"27.3","Cell RNA - HBEC3-KT [nTPM]":"18.6","Cell RNA - HBF TERT88 [nTPM]":"23.2","Cell RNA - HDLM-2 [nTPM]":"16.1","Cell RNA - HEK 293 [nTPM]":"14.4","Cell RNA - HEL [nTPM]":"60.4","Cell RNA - HeLa [nTPM]":"14.2","Cell RNA - Hep G2 [nTPM]":"10.3","Cell RNA - HHSteC [nTPM]":"14.8","Cell RNA - HL-60 [nTPM]":"27.3","Cell RNA - HMC-1 [nTPM]":"23.6","Cell RNA - HSkMC [nTPM]":"17.1","Cell RNA - hTCEpi [nTPM]":"19.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.4","Cell RNA - hTERT-HME1 [nTPM]":"24.8","Cell RNA - hTERT-RPE1 [nTPM]":"14.5","Cell RNA - HUVEC TERT2 [nTPM]":"18.8","Cell RNA - JURKAT [nTPM]":"29.7","Cell RNA - K-562 [nTPM]":"36.6","Cell RNA - Karpas-707 [nTPM]":"24.2","Cell RNA - LHCN-M2 [nTPM]":"16.0","Cell RNA - MCF7 [nTPM]":"10.4","Cell RNA - MOLT-4 [nTPM]":"59.9","Cell RNA - NB-4 [nTPM]":"9.4","Cell RNA - NTERA-2 [nTPM]":"12.8","Cell RNA - OE19 [nTPM]":"20.4","Cell RNA - PC-3 [nTPM]":"8.1","Cell RNA - REH [nTPM]":"37.7","Cell RNA - RH-30 [nTPM]":"39.1","Cell RNA - RPMI-8226 [nTPM]":"9.9","Cell RNA - RPTEC TERT1 [nTPM]":"11.0","Cell RNA - RT4 [nTPM]":"27.1","Cell RNA - SCLC-21H [nTPM]":"17.6","Cell RNA - SH-SY5Y [nTPM]":"16.7","Cell RNA - SiHa [nTPM]":"15.8","Cell RNA - SK-BR-3 [nTPM]":"12.4","Cell RNA - SK-MEL-30 [nTPM]":"13.8","Cell RNA - SuSa [nTPM]":"15.8","Cell RNA - T-47d [nTPM]":"26.3","Cell RNA - THP-1 [nTPM]":"12.9","Cell RNA - TIME [nTPM]":"25.5","Cell RNA - U-138 MG [nTPM]":"21.6","Cell RNA - U-2 OS [nTPM]":"15.3","Cell RNA - U-2197 [nTPM]":"21.1","Cell RNA - U-251 MG [nTPM]":"15.5","Cell RNA - U-266\/70 [nTPM]":"16.8","Cell RNA - U-266\/84 [nTPM]":"22.1","Cell RNA - U-698 [nTPM]":"33.8","Cell RNA - U-87 MG [nTPM]":"12.6","Cell RNA - U-937 [nTPM]":"14.1","Cell RNA - WM-115 [nTPM]":"17.3","Blood RNA - basophil [nTPM]":"2.5","Blood RNA - classical monocyte [nTPM]":"0.8","Blood RNA - eosinophil [nTPM]":"1.8","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"1.6","Blood RNA - memory B-cell [nTPM]":"1.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.6","Blood RNA - memory CD8 T-cell [nTPM]":"2.1","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"1.6","Blood RNA - naive CD4 T-cell [nTPM]":"1.9","Blood RNA - naive CD8 T-cell [nTPM]":"1.8","Blood RNA - neutrophil [nTPM]":"5.1","Blood RNA - NK-cell [nTPM]":"1.9","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"1.9","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"8.6","Brain RNA - basal ganglia [nTPM]":"12.7","Brain RNA - cerebellum [nTPM]":"20.1","Brain RNA - cerebral cortex [nTPM]":"10.5","Brain RNA - hippocampal formation [nTPM]":"9.1","Brain RNA - hypothalamus [nTPM]":"12.8","Brain RNA - medulla oblongata [nTPM]":"12.7","Brain RNA - midbrain [nTPM]":"12.4","Brain RNA - pons [nTPM]":"12.9","Brain RNA - spinal cord [nTPM]":"8.2","Brain RNA - thalamus [nTPM]":"10.1","Brain RNA - white matter [nTPM]":"16.7","Single Cell Type RNA - Adipocytes [nTPM]":"87.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"34.9","Single Cell Type RNA - Astrocytes [nTPM]":"64.0","Single Cell Type RNA - B-cells [nTPM]":"54.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"50.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.2","Single Cell Type RNA - Bipolar cells [nTPM]":"54.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"31.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"25.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"23.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"25.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"54.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.4","Single Cell Type RNA - dendritic cells [nTPM]":"61.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"14.2","Single Cell Type RNA - Early spermatids [nTPM]":"2.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"30.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"47.5","Single Cell Type RNA - Endothelial cells [nTPM]":"56.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"24.7","Single Cell Type RNA - Erythroid cells [nTPM]":"31.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"62.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.0","Single Cell Type RNA - Fibroblasts [nTPM]":"32.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"44.8","Single Cell Type RNA - granulocytes [nTPM]":"35.4","Single Cell Type RNA - Granulosa cells [nTPM]":"31.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"43.5","Single Cell Type RNA - Hepatocytes [nTPM]":"25.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.0","Single Cell Type RNA - Horizontal cells [nTPM]":"58.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"76.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.9","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"44.2","Single Cell Type RNA - Langerhans cells [nTPM]":"34.5","Single Cell Type RNA - Late spermatids [nTPM]":"4.8","Single Cell Type RNA - Leydig cells [nTPM]":"28.3","Single Cell Type RNA - Macrophages [nTPM]":"43.7","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"120.9","Single Cell Type RNA - monocytes [nTPM]":"30.3","Single Cell Type RNA - Muller glia cells [nTPM]":"27.9","Single Cell Type RNA - NK-cells [nTPM]":"61.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"93.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"129.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.7","Single Cell Type RNA - Paneth cells [nTPM]":"20.2","Single Cell Type RNA - Peritubular cells [nTPM]":"23.0","Single Cell Type RNA - Plasma cells [nTPM]":"38.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"44.9","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"49.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"34.6","Single Cell Type RNA - Spermatocytes [nTPM]":"37.8","Single Cell Type RNA - Spermatogonia [nTPM]":"37.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"61.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"21.1","Single Cell Type RNA - T-cells [nTPM]":"61.4","Single Cell Type RNA - Theca cells [nTPM]":"19.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.3","Single Cell Type RNA - Urothelial cells [nTPM]":"27.2"},{"Gene":"KAT6B","Gene synonym":["Morf","MOZ2","MYST4","qkf","querkopf","ZC2HC6B"],"Ensembl":"ENSG00000156650","Gene description":"Lysine acetyltransferase 6B","Uniprot":["Q8WYB5"],"Chromosome":"10","Position":"74824927-75032624","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","Acyltransferase","Chromatin regulator","Repressor","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"PC-3":"25.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006104"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA006104":"AB_1079445"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.82e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.6","Tissue RNA - adrenal gland [nTPM]":"6.3","Tissue RNA - amygdala [nTPM]":"5.0","Tissue RNA - appendix [nTPM]":"3.1","Tissue RNA - basal ganglia [nTPM]":"5.6","Tissue RNA - bone marrow [nTPM]":"8.8","Tissue RNA - breast [nTPM]":"7.3","Tissue RNA - cerebellum [nTPM]":"5.6","Tissue RNA - cerebral cortex [nTPM]":"5.3","Tissue RNA - cervix [nTPM]":"10.5","Tissue RNA - choroid plexus [nTPM]":"2.0","Tissue RNA - colon [nTPM]":"9.6","Tissue RNA - duodenum [nTPM]":"3.2","Tissue RNA - endometrium 1 [nTPM]":"9.2","Tissue RNA - epididymis [nTPM]":"5.2","Tissue RNA - esophagus [nTPM]":"6.9","Tissue RNA - fallopian tube [nTPM]":"8.3","Tissue RNA - gallbladder [nTPM]":"3.8","Tissue RNA - heart muscle [nTPM]":"7.5","Tissue RNA - hippocampal formation [nTPM]":"5.7","Tissue RNA - hypothalamus [nTPM]":"4.0","Tissue RNA - kidney [nTPM]":"4.3","Tissue RNA - liver [nTPM]":"4.6","Tissue RNA - lung [nTPM]":"6.5","Tissue RNA - lymph node [nTPM]":"4.4","Tissue RNA - medulla oblongata [nTPM]":"3.1","Tissue RNA - midbrain [nTPM]":"3.5","Tissue RNA - ovary [nTPM]":"12.2","Tissue RNA - pancreas [nTPM]":"8.6","Tissue RNA - parathyroid gland [nTPM]":"10.5","Tissue RNA - pituitary gland [nTPM]":"7.4","Tissue RNA - placenta [nTPM]":"4.4","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"6.5","Tissue RNA - rectum [nTPM]":"4.1","Tissue RNA - retina [nTPM]":"6.4","Tissue RNA - salivary gland [nTPM]":"7.3","Tissue RNA - seminal vesicle [nTPM]":"4.3","Tissue RNA - skeletal muscle [nTPM]":"11.8","Tissue RNA - skin 1 [nTPM]":"8.0","Tissue RNA - small intestine [nTPM]":"8.1","Tissue RNA - smooth muscle [nTPM]":"6.0","Tissue RNA - spinal cord [nTPM]":"3.0","Tissue RNA - spleen [nTPM]":"5.4","Tissue RNA - stomach 1 [nTPM]":"9.3","Tissue RNA - testis [nTPM]":"7.8","Tissue RNA - thalamus [nTPM]":"5.6","Tissue RNA - thymus [nTPM]":"9.8","Tissue RNA - thyroid gland [nTPM]":"7.3","Tissue RNA - tongue [nTPM]":"6.0","Tissue RNA - tonsil [nTPM]":"4.1","Tissue RNA - urinary bladder [nTPM]":"9.1","Tissue RNA - vagina [nTPM]":"8.9","Tissue RNA - white matter [nTPM]":"4.9","Cell RNA - A-431 [nTPM]":"4.7","Cell RNA - A549 [nTPM]":"4.4","Cell RNA - AF22 [nTPM]":"8.0","Cell RNA - AN3-CA [nTPM]":"6.9","Cell RNA - ASC diff [nTPM]":"6.2","Cell RNA - ASC TERT1 [nTPM]":"9.2","Cell RNA - BEWO [nTPM]":"4.1","Cell RNA - BJ [nTPM]":"4.1","Cell RNA - BJ hTERT+ [nTPM]":"7.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.6","Cell RNA - CACO-2 [nTPM]":"3.4","Cell RNA - CAPAN-2 [nTPM]":"5.3","Cell RNA - Daudi [nTPM]":"9.8","Cell RNA - EFO-21 [nTPM]":"2.1","Cell RNA - fHDF\/TERT166 [nTPM]":"7.1","Cell RNA - GAMG [nTPM]":"3.5","Cell RNA - HaCaT [nTPM]":"3.8","Cell RNA - HAP1 [nTPM]":"4.2","Cell RNA - HBEC3-KT [nTPM]":"3.3","Cell RNA - HBF TERT88 [nTPM]":"5.6","Cell RNA - HDLM-2 [nTPM]":"4.2","Cell RNA - HEK 293 [nTPM]":"6.8","Cell RNA - HEL [nTPM]":"3.6","Cell RNA - HeLa [nTPM]":"3.9","Cell RNA - Hep G2 [nTPM]":"4.5","Cell RNA - HHSteC [nTPM]":"4.5","Cell RNA - HL-60 [nTPM]":"8.6","Cell RNA - HMC-1 [nTPM]":"2.4","Cell RNA - HSkMC [nTPM]":"5.9","Cell RNA - hTCEpi [nTPM]":"5.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.5","Cell RNA - hTERT-HME1 [nTPM]":"6.9","Cell RNA - hTERT-RPE1 [nTPM]":"10.5","Cell RNA - HUVEC TERT2 [nTPM]":"3.8","Cell RNA - JURKAT [nTPM]":"7.7","Cell RNA - K-562 [nTPM]":"3.9","Cell RNA - Karpas-707 [nTPM]":"9.0","Cell RNA - LHCN-M2 [nTPM]":"4.2","Cell RNA - MCF7 [nTPM]":"4.7","Cell RNA - MOLT-4 [nTPM]":"8.2","Cell RNA - NB-4 [nTPM]":"4.3","Cell RNA - NTERA-2 [nTPM]":"5.0","Cell RNA - OE19 [nTPM]":"4.9","Cell RNA - PC-3 [nTPM]":"25.7","Cell RNA - REH [nTPM]":"12.7","Cell RNA - RH-30 [nTPM]":"4.3","Cell RNA - RPMI-8226 [nTPM]":"2.4","Cell RNA - RPTEC TERT1 [nTPM]":"2.3","Cell RNA - RT4 [nTPM]":"2.3","Cell RNA - SCLC-21H [nTPM]":"4.2","Cell RNA - SH-SY5Y [nTPM]":"6.9","Cell RNA - SiHa [nTPM]":"4.1","Cell RNA - SK-BR-3 [nTPM]":"7.4","Cell RNA - SK-MEL-30 [nTPM]":"3.7","Cell RNA - SuSa [nTPM]":"2.8","Cell RNA - T-47d [nTPM]":"4.5","Cell RNA - THP-1 [nTPM]":"3.2","Cell RNA - TIME [nTPM]":"4.7","Cell RNA - U-138 MG [nTPM]":"4.6","Cell RNA - U-2 OS [nTPM]":"5.5","Cell RNA - U-2197 [nTPM]":"3.1","Cell RNA - U-251 MG [nTPM]":"3.8","Cell RNA - U-266\/70 [nTPM]":"6.4","Cell RNA - U-266\/84 [nTPM]":"8.1","Cell RNA - U-698 [nTPM]":"6.4","Cell RNA - U-87 MG [nTPM]":"5.0","Cell RNA - U-937 [nTPM]":"8.9","Cell RNA - WM-115 [nTPM]":"1.3","Blood RNA - basophil [nTPM]":"1.7","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"1.6","Blood RNA - gdT-cell [nTPM]":"2.3","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"2.6","Blood RNA - memory B-cell [nTPM]":"2.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.9","Blood RNA - memory CD8 T-cell [nTPM]":"2.1","Blood RNA - myeloid DC [nTPM]":"1.1","Blood RNA - naive B-cell [nTPM]":"2.8","Blood RNA - naive CD4 T-cell [nTPM]":"2.9","Blood RNA - naive CD8 T-cell [nTPM]":"2.6","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"4.4","Blood RNA - non-classical monocyte [nTPM]":"1.1","Blood RNA - plasmacytoid DC [nTPM]":"1.7","Blood RNA - T-reg [nTPM]":"1.7","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"5.0","Brain RNA - basal ganglia [nTPM]":"5.6","Brain RNA - cerebellum [nTPM]":"5.6","Brain RNA - cerebral cortex [nTPM]":"5.3","Brain RNA - hippocampal formation [nTPM]":"5.7","Brain RNA - hypothalamus [nTPM]":"4.0","Brain RNA - medulla oblongata [nTPM]":"3.1","Brain RNA - midbrain [nTPM]":"3.5","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"3.0","Brain RNA - thalamus [nTPM]":"5.6","Brain RNA - white matter [nTPM]":"4.9","Single Cell Type RNA - Adipocytes [nTPM]":"34.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"53.7","Single Cell Type RNA - Astrocytes [nTPM]":"90.1","Single Cell Type RNA - B-cells [nTPM]":"48.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"19.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"74.6","Single Cell Type RNA - Bipolar cells [nTPM]":"52.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"36.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"27.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"53.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"29.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"68.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.4","Single Cell Type RNA - dendritic cells [nTPM]":"51.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"22.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"12.7","Single Cell Type RNA - Early spermatids [nTPM]":"6.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"41.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"72.7","Single Cell Type RNA - Endothelial cells [nTPM]":"24.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"23.8","Single Cell Type RNA - Erythroid cells [nTPM]":"32.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"130.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.6","Single Cell Type RNA - Fibroblasts [nTPM]":"44.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"57.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"50.8","Single Cell Type RNA - granulocytes [nTPM]":"41.7","Single Cell Type RNA - Granulosa cells [nTPM]":"68.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.9","Single Cell Type RNA - Hepatocytes [nTPM]":"16.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.0","Single Cell Type RNA - Horizontal cells [nTPM]":"43.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"131.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.7","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"12.3","Single Cell Type RNA - Langerhans cells [nTPM]":"15.0","Single Cell Type RNA - Late spermatids [nTPM]":"8.3","Single Cell Type RNA - Leydig cells [nTPM]":"42.3","Single Cell Type RNA - Macrophages [nTPM]":"24.1","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"41.2","Single Cell Type RNA - monocytes [nTPM]":"13.6","Single Cell Type RNA - Muller glia cells [nTPM]":"45.5","Single Cell Type RNA - NK-cells [nTPM]":"42.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"101.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"92.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.5","Single Cell Type RNA - Paneth cells [nTPM]":"19.4","Single Cell Type RNA - Peritubular cells [nTPM]":"40.3","Single Cell Type RNA - Plasma cells [nTPM]":"62.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"21.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"52.5","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"55.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"44.1","Single Cell Type RNA - Spermatocytes [nTPM]":"33.1","Single Cell Type RNA - Spermatogonia [nTPM]":"32.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"46.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.7","Single Cell Type RNA - T-cells [nTPM]":"59.7","Single Cell Type RNA - Theca cells [nTPM]":"27.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.5","Single Cell Type RNA - Urothelial cells [nTPM]":"23.5"},{"Gene":"KCNE5","Gene synonym":["KCNE1L"],"Ensembl":"ENSG00000176076","Gene description":"Potassium voltage-gated channel subfamily E regulatory subunit 5","Uniprot":["Q9UJ90"],"Chromosome":"X","Position":"109623700-109625172","Protein class":["Disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Alport syndrome","Deafness","Elliptocytosis","Hereditary hemolytic anemia","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"9.8","skeletal muscle":"4.0","tongue":"4.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"4.6","Erythroid cells":"3.8","monocytes":"9.4","Muller glia cells":"5.3","Peritubular cells":"3.8"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"glioma":"7.9","testis cancer":"2.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"2.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"1.5","hTEC\/SVTERT24-B":"2.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042316"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 65: Plasmacytoid DCs - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA042316":"AB_10795397"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-3"},"Tissue RNA - adipose tissue [nTPM]":"1.1","Tissue RNA - adrenal gland [nTPM]":"0.8","Tissue RNA - amygdala [nTPM]":"3.2","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"5.4","Tissue RNA - bone marrow [nTPM]":"1.6","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"9.4","Tissue RNA - cerebral cortex [nTPM]":"2.7","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.7","Tissue RNA - hippocampal formation [nTPM]":"2.7","Tissue RNA - hypothalamus [nTPM]":"6.6","Tissue RNA - kidney [nTPM]":"0.7","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"6.3","Tissue RNA - midbrain [nTPM]":"9.8","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"6.9","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"4.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"4.0","Tissue RNA - spleen [nTPM]":"0.9","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"7.8","Tissue RNA - thymus [nTPM]":"2.3","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"4.9","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"4.6","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.7","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.8","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"1.0","Cell RNA - HeLa [nTPM]":"1.1","Cell RNA - Hep G2 [nTPM]":"0.7","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.5","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.0","Cell RNA - hTERT-HME1 [nTPM]":"0.5","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"1.3","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.3","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.5","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.9","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.7","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"2.2","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"3.2","Brain RNA - basal ganglia [nTPM]":"5.4","Brain RNA - cerebellum [nTPM]":"9.4","Brain RNA - cerebral cortex [nTPM]":"2.7","Brain RNA - hippocampal formation [nTPM]":"2.7","Brain RNA - hypothalamus [nTPM]":"6.6","Brain RNA - medulla oblongata [nTPM]":"6.3","Brain RNA - midbrain [nTPM]":"9.8","Brain RNA - pons [nTPM]":"6.9","Brain RNA - spinal cord [nTPM]":"4.0","Brain RNA - thalamus [nTPM]":"7.8","Brain RNA - white matter [nTPM]":"4.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"4.6","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"2.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.2","Single Cell Type RNA - Fibroblasts [nTPM]":"1.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"2.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"9.4","Single Cell Type RNA - Muller glia cells [nTPM]":"5.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"KCNH1","Gene synonym":["eag","eag1","h-eag","hEAG","Kv10.1"],"Ensembl":"ENSG00000143473","Gene description":"Potassium voltage-gated channel subfamily H member 1","Uniprot":["O95259"],"Chromosome":"1","Position":"210676823-211134165","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Calmodulin-binding","Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"17.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"533.5","Inhibitory neurons":"261.0","Oligodendrocytes":"116.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"LHCN-M2":"6.2","RH-30":"10.1","RPTEC TERT1":"6.0","SH-SY5Y":"12.9","SK-MEL-30":"12.9","T-47d":"9.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"basal ganglia":"34.0","cerebellum":"19.1","cerebral cortex":"23.9","hippocampal formation":"17.9","olfactory bulb":"8.9"},"Antibody":["HPA014551","HPA019445","HPA076421"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA014551":"AB_2669038","HPA019445":"AB_1852118","HPA076421":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.9","Tissue RNA - amygdala [nTPM]":"6.8","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"9.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"9.5","Tissue RNA - cerebral cortex [nTPM]":"17.9","Tissue RNA - cervix [nTPM]":"0.7","Tissue RNA - choroid plexus [nTPM]":"2.7","Tissue RNA - colon [nTPM]":"0.5","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.6","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"11.2","Tissue RNA - hypothalamus [nTPM]":"5.3","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"4.8","Tissue RNA - midbrain [nTPM]":"4.4","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.7","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"4.0","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.8","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"4.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"1.5","Tissue RNA - thalamus [nTPM]":"4.9","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"8.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"2.1","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"1.0","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.4","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"1.4","Cell RNA - GAMG [nTPM]":"2.4","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.9","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.6","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.4","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"6.2","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"10.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"6.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"12.9","Cell RNA - SiHa [nTPM]":"2.4","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"12.9","Cell RNA - SuSa [nTPM]":"1.7","Cell RNA - T-47d [nTPM]":"9.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"1.6","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"2.0","Cell RNA - U-251 MG [nTPM]":"1.2","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.8","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"6.8","Brain RNA - basal ganglia [nTPM]":"9.2","Brain RNA - cerebellum [nTPM]":"9.5","Brain RNA - cerebral cortex [nTPM]":"17.9","Brain RNA - hippocampal formation [nTPM]":"11.2","Brain RNA - hypothalamus [nTPM]":"5.3","Brain RNA - medulla oblongata [nTPM]":"4.8","Brain RNA - midbrain [nTPM]":"4.4","Brain RNA - pons [nTPM]":"4.0","Brain RNA - spinal cord [nTPM]":"4.0","Brain RNA - thalamus [nTPM]":"4.9","Brain RNA - white matter [nTPM]":"8.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"8.8","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"11.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.8","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"533.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"261.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"18.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"116.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"KCNJ13","Gene synonym":["Kir1.4","Kir7.1","LCA16"],"Ensembl":"ENSG00000115474","Gene description":"Potassium inwardly rectifying channel subfamily J member 13","Uniprot":["O60928"],"Chromosome":"2","Position":"232765802-232776565","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Voltage-gated channel"],"Disease involvement":["Cataract","Disease variant","Leber congenital amaurosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"choroid plexus":"159.5","intestine":"91.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Muller glia cells":"54.8","Proximal enterocytes":"217.4","Undifferentiated cells":"68.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"melanoma":"5.9"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebellum":"7.3","hippocampal formation":"8.0","thalamus":"5.3","white matter":"3.4"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-2197":"1.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051609"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA051609":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.03e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"1.3","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"7.3","Tissue RNA - cerebral cortex [nTPM]":"1.1","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"159.5","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"7.9","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"2.2","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"8.0","Tissue RNA - hypothalamus [nTPM]":"0.4","Tissue RNA - kidney [nTPM]":"3.3","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"1.3","Tissue RNA - midbrain [nTPM]":"0.8","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"15.8","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"1.3","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"13.7","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"1.1","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"3.2","Tissue RNA - small intestine [nTPM]":"91.3","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.4","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"2.3","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"5.3","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"7.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"3.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.7","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.8","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"1.2","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"1.9","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"1.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"1.3","Brain RNA - cerebellum [nTPM]":"7.3","Brain RNA - cerebral cortex [nTPM]":"1.1","Brain RNA - hippocampal formation [nTPM]":"8.0","Brain RNA - hypothalamus [nTPM]":"0.4","Brain RNA - medulla oblongata [nTPM]":"1.3","Brain RNA - midbrain [nTPM]":"0.8","Brain RNA - pons [nTPM]":"1.3","Brain RNA - spinal cord [nTPM]":"0.4","Brain RNA - thalamus [nTPM]":"5.3","Brain RNA - white matter [nTPM]":"3.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.8","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"25.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"54.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"8.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"217.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"68.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"KCNJ5","Gene synonym":["CIR","GIRK4","KATP1","Kir3.4","LQT13"],"Ensembl":"ENSG00000120457","Gene description":"Potassium inwardly rectifying channel subfamily J member 5","Uniprot":["P48544"],"Chromosome":"11","Position":"128891356-128921163","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Voltage-gated channel"],"Disease involvement":["Cancer-related genes","Disease variant","Long QT syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"64.3","pancreas":"20.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hofbauer cells":"48.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"13","RNA cell line specific nTPM":{"HBEC3-KT":"13.3"},"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"6","RNA mouse brain regional specific nTPM":{"basal ganglia":"2.9","hypothalamus":"6.8","midbrain":"1.9","thalamus":"3.6"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014722","HPA017353","CAB022569"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022569":null,"HPA014722":"AB_1852133","HPA017353":"AB_1852135"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.5","Tissue RNA - adrenal gland [nTPM]":"64.3","Tissue RNA - amygdala [nTPM]":"1.2","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"0.9","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"0.9","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"2.0","Tissue RNA - cervix [nTPM]":"1.3","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.8","Tissue RNA - duodenum [nTPM]":"0.8","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"1.0","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"2.2","Tissue RNA - heart muscle [nTPM]":"8.5","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"3.2","Tissue RNA - kidney [nTPM]":"5.4","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"5.9","Tissue RNA - lymph node [nTPM]":"1.6","Tissue RNA - medulla oblongata [nTPM]":"3.7","Tissue RNA - midbrain [nTPM]":"1.7","Tissue RNA - ovary [nTPM]":"0.9","Tissue RNA - pancreas [nTPM]":"20.4","Tissue RNA - parathyroid gland [nTPM]":"1.3","Tissue RNA - pituitary gland [nTPM]":"11.9","Tissue RNA - placenta [nTPM]":"7.3","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"1.3","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"1.0","Tissue RNA - salivary gland [nTPM]":"0.9","Tissue RNA - seminal vesicle [nTPM]":"9.6","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"1.7","Tissue RNA - spleen [nTPM]":"13.6","Tissue RNA - stomach 1 [nTPM]":"2.3","Tissue RNA - testis [nTPM]":"1.1","Tissue RNA - thalamus [nTPM]":"7.9","Tissue RNA - thymus [nTPM]":"5.8","Tissue RNA - thyroid gland [nTPM]":"0.5","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"1.5","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"3.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"13.3","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.6","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.6","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"1.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"1.2","Brain RNA - basal ganglia [nTPM]":"0.9","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"2.0","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"3.2","Brain RNA - medulla oblongata [nTPM]":"3.7","Brain RNA - midbrain [nTPM]":"1.7","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"1.7","Brain RNA - thalamus [nTPM]":"7.9","Brain RNA - white matter [nTPM]":"3.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"2.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"2.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"1.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"48.3","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.2","Single Cell Type RNA - Langerhans cells [nTPM]":"2.9","Single Cell Type RNA - Late spermatids [nTPM]":"7.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"10.9","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"1.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.9","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"2.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"KCNJ6","Gene synonym":["BIR1","GIRK2","hiGIRK2","KATP2","KCNJ7","Kir3.2"],"Ensembl":"ENSG00000157542","Gene description":"Potassium inwardly rectifying channel subfamily J member 6","Uniprot":["P48051"],"Chromosome":"21","Position":"37607373-38121345","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Voltage-gated channel"],"Disease involvement":["Congenital generalized lipodystrophy","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"brain":"24.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"152.6","Horizontal cells":"245.6","Inhibitory neurons":"146.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"cerebral cortex":"10.3","hippocampal formation":"10.6","midbrain":"24.2"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"2.2","eosinophil":"1.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"granulocytes":"2.2"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"LHCN-M2":"29.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 62: Horizontal cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"2.3","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"2.7","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"1.6","Tissue RNA - cerebral cortex [nTPM]":"10.3","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"10.6","Tissue RNA - hypothalamus [nTPM]":"1.9","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"1.9","Tissue RNA - midbrain [nTPM]":"24.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.7","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"2.2","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"1.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"1.2","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"1.8","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"1.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.7","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"1.8","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.9","Cell RNA - hTERT-HME1 [nTPM]":"1.6","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"3.5","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"29.2","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"2.8","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"1.0","Cell RNA - RPTEC TERT1 [nTPM]":"4.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.7","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"4.4","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"4.3","Cell RNA - U-266\/84 [nTPM]":"1.2","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"2.2","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"1.3","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.3","Brain RNA - basal ganglia [nTPM]":"2.7","Brain RNA - cerebellum [nTPM]":"1.6","Brain RNA - cerebral cortex [nTPM]":"10.3","Brain RNA - hippocampal formation [nTPM]":"10.6","Brain RNA - hypothalamus [nTPM]":"1.9","Brain RNA - medulla oblongata [nTPM]":"1.9","Brain RNA - midbrain [nTPM]":"24.2","Brain RNA - pons [nTPM]":"2.2","Brain RNA - spinal cord [nTPM]":"1.2","Brain RNA - thalamus [nTPM]":"1.8","Brain RNA - white matter [nTPM]":"1.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"2.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"25.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"34.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"1.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"41.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"152.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"0.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"245.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"146.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.8","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"38.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"1.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"KCNK18","Gene synonym":["K2p18.1","TRESK","TRESK-2","TRESK2","TRIK"],"Ensembl":"ENSG00000186795","Gene description":"Potassium two pore domain channel subfamily K member 18","Uniprot":["Q7Z418"],"Chromosome":"10","Position":"117197489-117210299","Protein class":["Disease related genes","Potential drug targets","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"1.3"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044739"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044739":"AB_10795008"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"1.3","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.7","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.7","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"KCNK4","Gene synonym":["K2p4.1","TRAAK"],"Ensembl":"ENSG00000182450","Gene description":"Potassium two pore domain channel subfamily K member 4","Uniprot":["Q9NYG8"],"Chromosome":"11","Position":"64291302-64300031","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"28","RNA tissue specific nTPM":{"brain":"6.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"2.9","Endometrial stromal cells":"9.8","Excitatory neurons":"9.0","Extravillous trophoblasts":"3.6","Horizontal cells":"3.3","Muller glia cells":"4.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 36: Stromal cells - Cell proliferation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"5.7","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"4.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"6.9","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"6.1","Tissue RNA - hypothalamus [nTPM]":"0.7","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.6","Tissue RNA - midbrain [nTPM]":"0.6","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.6","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"1.3","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"3.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"5.7","Brain RNA - basal ganglia [nTPM]":"4.1","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"6.9","Brain RNA - hippocampal formation [nTPM]":"6.1","Brain RNA - hypothalamus [nTPM]":"0.7","Brain RNA - medulla oblongata [nTPM]":"0.6","Brain RNA - midbrain [nTPM]":"0.6","Brain RNA - pons [nTPM]":"0.6","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"1.3","Brain RNA - white matter [nTPM]":"3.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.9","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.8","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.6","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.9","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"KCNQ2","Gene synonym":["BFNC","EBN","EBN1","ENB1","HNSPC","KCNA11","Kv7.2"],"Ensembl":"ENSG00000075043","Gene description":"Potassium voltage-gated channel subfamily Q member 2","Uniprot":["O43526"],"Chromosome":"20","Position":"63400208-63472677","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"91.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"16.5","Excitatory neurons":"61.7","Horizontal cells":"13.5","Inhibitory neurons":"37.5","Oligodendrocyte precursor cells":"50.8","Spermatogonia":"28.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"glioma":"8.7"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"amygdala":"55.7","basal ganglia":"37.2","cerebellum":"27.8","cerebral cortex":"91.9","hippocampal formation":"68.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"21.2","AN3-CA":"35.0","NTERA-2":"19.3","SCLC-21H":"67.8","SH-SY5Y":"119.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016642","HPA057112"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA016642":"AB_1855555","HPA057112":"AB_2683339"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"6.2","Tissue RNA - amygdala [nTPM]":"55.7","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"37.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"27.8","Tissue RNA - cerebral cortex [nTPM]":"91.9","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.6","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"68.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"2.6","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"1.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"19.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"1.6","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"2.2","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"10.6","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"12.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"21.2","Cell RNA - AN3-CA [nTPM]":"35.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"8.3","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"2.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"19.3","Cell RNA - OE19 [nTPM]":"0.5","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"67.8","Cell RNA - SH-SY5Y [nTPM]":"119.3","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.8","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"55.7","Brain RNA - basal ganglia [nTPM]":"37.2","Brain RNA - cerebellum [nTPM]":"27.8","Brain RNA - cerebral cortex [nTPM]":"91.9","Brain RNA - hippocampal formation [nTPM]":"68.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"2.6","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"12.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"7.2","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"5.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"16.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"61.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"8.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"50.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"7.4","Single Cell Type RNA - Spermatogonia [nTPM]":"28.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"KCNQ3","Gene synonym":["EBN2","Kv7.3"],"Ensembl":"ENSG00000184156","Gene description":"Potassium voltage-gated channel subfamily Q member 3","Uniprot":["O43525"],"Chromosome":"8","Position":"132120859-132481095","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"23.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"501.5","Inhibitory neurons":"485.6","Microglial cells":"502.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"2.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTERT-HME1":"6.6","JURKAT":"3.8","RPMI-8226":"2.8","U-2 OS":"4.3","U-87 MG":"3.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.3","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"9.9","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"21.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.9","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"23.7","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.7","Tissue RNA - hippocampal formation [nTPM]":"9.1","Tissue RNA - hypothalamus [nTPM]":"4.7","Tissue RNA - kidney [nTPM]":"0.7","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"1.9","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"4.7","Tissue RNA - midbrain [nTPM]":"8.1","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.9","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"1.9","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"7.4","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"2.5","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"0.6","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"16.0","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"0.5","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"8.7","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.3","Cell RNA - ASC TERT1 [nTPM]":"1.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"1.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"1.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.2","Cell RNA - fHDF\/TERT166 [nTPM]":"1.5","Cell RNA - GAMG [nTPM]":"2.5","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"2.5","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"1.7","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.7","Cell RNA - hTERT-HME1 [nTPM]":"6.6","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"3.8","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.9","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"2.8","Cell RNA - RPTEC TERT1 [nTPM]":"1.6","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.3","Cell RNA - SH-SY5Y [nTPM]":"1.2","Cell RNA - SiHa [nTPM]":"0.4","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"1.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"4.3","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"3.6","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"9.9","Brain RNA - basal ganglia [nTPM]":"21.2","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"23.7","Brain RNA - hippocampal formation [nTPM]":"9.1","Brain RNA - hypothalamus [nTPM]":"4.7","Brain RNA - medulla oblongata [nTPM]":"4.7","Brain RNA - midbrain [nTPM]":"8.1","Brain RNA - pons [nTPM]":"7.4","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"16.0","Brain RNA - white matter [nTPM]":"8.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.0","Single Cell Type RNA - Astrocytes [nTPM]":"84.5","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"6.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"4.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.2","Single Cell Type RNA - Endothelial cells [nTPM]":"2.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"501.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"485.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1.6","Single Cell Type RNA - Late spermatids [nTPM]":"2.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"2.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"502.2","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"117.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"31.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"KCNQ4","Gene synonym":["DFNA2","Kv7.4"],"Ensembl":"ENSG00000117013","Gene description":"Potassium voltage-gated channel subfamily Q member 4","Uniprot":["P56696"],"Chromosome":"1","Position":"40783787-40840452","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Hearing","Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"5.1","intestine":"5.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"5.1","Inhibitory neurons":"9.7","Muller glia cells":"4.2","Sertoli cells":"6.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"midbrain":"5.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HAP1":"1.8","HEK 293":"2.2","K-562":"2.6","MCF7":"1.4","REH":"1.3","THP-1":"1.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018305"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018305":"AB_1855556"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.9","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.6","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"1.7","Tissue RNA - cervix [nTPM]":"0.9","Tissue RNA - choroid plexus [nTPM]":"2.4","Tissue RNA - colon [nTPM]":"5.4","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"2.8","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"1.0","Tissue RNA - fallopian tube [nTPM]":"2.3","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.6","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.5","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.7","Tissue RNA - midbrain [nTPM]":"5.1","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"0.7","Tissue RNA - prostate [nTPM]":"1.1","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"1.4","Tissue RNA - seminal vesicle [nTPM]":"1.1","Tissue RNA - skeletal muscle [nTPM]":"3.2","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"1.2","Tissue RNA - smooth muscle [nTPM]":"1.5","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"1.3","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"1.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"2.3","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"2.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.8","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.6","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"1.8","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"2.2","Cell RNA - HEL [nTPM]":"0.9","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"2.6","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.4","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"1.3","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.1","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"1.4","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"1.7","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.7","Brain RNA - midbrain [nTPM]":"5.1","Brain RNA - pons [nTPM]":"0.7","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"2.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"KCNQ5","Gene synonym":["Kv7.5"],"Ensembl":"ENSG00000185760","Gene description":"Potassium voltage-gated channel subfamily Q member 5","Uniprot":["Q9NR82"],"Chromosome":"6","Position":"72621792-73198853","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"28.3","skeletal muscle":"21.1","tongue":"12.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"30","RNA single cell type specific nTPM":{"Excitatory neurons":"2136.7","Inhibitory neurons":"862.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"28.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ":"34.9","HEL":"23.2","HL-60":"31.5","U-251 MG":"23.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016655"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 47: Non-specific - Unknown function","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA016655":"AB_1855557"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"1.6","Tissue RNA - amygdala [nTPM]":"1.2","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"7.5","Tissue RNA - bone marrow [nTPM]":"5.1","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"28.3","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.9","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"4.3","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"17.4","Tissue RNA - midbrain [nTPM]":"1.0","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"19.4","Tissue RNA - prostate [nTPM]":"1.3","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"1.2","Tissue RNA - seminal vesicle [nTPM]":"0.9","Tissue RNA - skeletal muscle [nTPM]":"21.1","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.7","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"1.1","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"1.7","Tissue RNA - thyroid gland [nTPM]":"4.7","Tissue RNA - tongue [nTPM]":"12.2","Tissue RNA - tonsil [nTPM]":"2.0","Tissue RNA - urinary bladder [nTPM]":"0.9","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"4.6","Cell RNA - A-431 [nTPM]":"4.4","Cell RNA - A549 [nTPM]":"1.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"1.5","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"34.9","Cell RNA - BJ hTERT+ [nTPM]":"5.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.3","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"21.2","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"11.9","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"0.7","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"2.1","Cell RNA - HBF TERT88 [nTPM]":"6.1","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"7.2","Cell RNA - HEL [nTPM]":"23.2","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.9","Cell RNA - HL-60 [nTPM]":"31.5","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.5","Cell RNA - hTERT-HME1 [nTPM]":"14.9","Cell RNA - hTERT-RPE1 [nTPM]":"3.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"1.4","Cell RNA - Karpas-707 [nTPM]":"14.2","Cell RNA - LHCN-M2 [nTPM]":"10.2","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"13.5","Cell RNA - NTERA-2 [nTPM]":"1.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"7.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"1.1","Cell RNA - RPMI-8226 [nTPM]":"14.4","Cell RNA - RPTEC TERT1 [nTPM]":"1.9","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"5.8","Cell RNA - SH-SY5Y [nTPM]":"2.7","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"13.7","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"4.3","Cell RNA - THP-1 [nTPM]":"2.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"21.0","Cell RNA - U-2 OS [nTPM]":"9.2","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"23.4","Cell RNA - U-266\/70 [nTPM]":"14.8","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"9.3","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"14.9","Cell RNA - WM-115 [nTPM]":"1.2","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.2","Brain RNA - basal ganglia [nTPM]":"7.5","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"28.3","Brain RNA - hippocampal formation [nTPM]":"4.3","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"17.4","Brain RNA - midbrain [nTPM]":"1.0","Brain RNA - pons [nTPM]":"19.4","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"4.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"38.8","Single Cell Type RNA - B-cells [nTPM]":"7.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"2.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"2136.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"862.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"49.6","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"30.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"26.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"7.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"2.8","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"KCNT1","Gene synonym":["KCa4.1","KIAA1422","SLACK","Slo2.2"],"Ensembl":"ENSG00000107147","Gene description":"Potassium sodium-activated channel subfamily T member 1","Uniprot":["Q5JUK3"],"Chromosome":"9","Position":"135702185-135795508","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"37.1","lymphoid tissue":"15.8","skeletal muscle":"13.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Excitatory neurons":"60.1","Inhibitory neurons":"55.0","Theca cells":"21.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"0.8"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"37.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"OE19":"2.5","RPMI-8226":"1.8","SCLC-21H":"3.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"42.8"},"Antibody":["HPA059880"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 47: Non-specific - Unknown function","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA059880":"AB_2684149"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-13"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"3.9","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"7.9","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"1.9","Tissue RNA - cerebral cortex [nTPM]":"37.1","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.6","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"1.2","Tissue RNA - hippocampal formation [nTPM]":"4.2","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"4.5","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"5.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"8.7","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"2.8","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"13.4","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"15.8","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"8.2","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"12.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"2.5","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.8","Cell RNA - RPMI-8226 [nTPM]":"1.8","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"3.7","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.9","Brain RNA - basal ganglia [nTPM]":"7.9","Brain RNA - cerebellum [nTPM]":"1.9","Brain RNA - cerebral cortex [nTPM]":"37.1","Brain RNA - hippocampal formation [nTPM]":"4.2","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"4.5","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"2.8","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"12.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"3.6","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"60.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"55.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"21.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"KCNT2","Gene synonym":["KCa4.2","SLICK","SLO2.1"],"Ensembl":"ENSG00000162687","Gene description":"Potassium sodium-activated channel subfamily T member 2","Uniprot":["Q6UVM3"],"Chromosome":"1","Position":"196225779-196609225","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"ovary":"3.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"220.2","Inhibitory neurons":"240.5","Oligodendrocyte precursor cells":"310.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"1.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HHSteC":"3.2","hTERT-RPE1":"9.0","SCLC-21H":"7.5","SH-SY5Y":"5.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051218"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA051218":"AB_2681392"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.67e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-3"},"Tissue RNA - adipose tissue [nTPM]":"1.0","Tissue RNA - adrenal gland [nTPM]":"0.6","Tissue RNA - amygdala [nTPM]":"0.9","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"2.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"2.0","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"0.5","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"1.0","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"1.4","Tissue RNA - heart muscle [nTPM]":"1.8","Tissue RNA - hippocampal formation [nTPM]":"2.5","Tissue RNA - hypothalamus [nTPM]":"3.3","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"2.8","Tissue RNA - lung [nTPM]":"1.8","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"3.8","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.9","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"1.0","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"1.1","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"1.1","Tissue RNA - tongue [nTPM]":"0.8","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.8","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"1.8","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"1.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.8","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.7","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.9","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"3.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"1.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.4","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"9.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"2.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"7.5","Cell RNA - SH-SY5Y [nTPM]":"5.6","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"1.9","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.9","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.9","Brain RNA - basal ganglia [nTPM]":"2.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"2.0","Brain RNA - hippocampal formation [nTPM]":"2.5","Brain RNA - hypothalamus [nTPM]":"3.3","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"13.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"220.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"9.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"6.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"6.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"240.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"3.3","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"58.1","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"310.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"3.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"KCNV2","Gene synonym":["Kv8.2"],"Ensembl":"ENSG00000168263","Gene description":"Potassium voltage-gated channel modifier subfamily V member 2","Uniprot":["Q8TDN2"],"Chromosome":"9","Position":"2717510-2730037","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Cone-rod dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"59","RNA tissue specific nTPM":{"retina":"289.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"515.0","Rod photoreceptor cells":"530.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"78","RNA cancer specific FPKM":{"testis cancer":"6.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031131"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031131":"AB_10609996"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"1.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"1.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"1.3","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.9","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"289.1","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"4.9","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.5","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.1","Brain RNA - basal ganglia [nTPM]":"1.0","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"1.3","Brain RNA - hippocampal formation [nTPM]":"0.9","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"49.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"515.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"81.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"2.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"25.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"69.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"530.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"7.4","Single Cell Type RNA - Spermatogonia [nTPM]":"14.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"KDM1A","Gene synonym":["AOF2","BHC110","KDM1","KIAA0601","LSD1"],"Ensembl":"ENSG00000004487","Gene description":"Lysine demethylase 1A","Uniprot":["O60341"],"Chromosome":"1","Position":"23019443-23083689","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","Developmental protein","Oxidoreductase","Repressor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"131.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005884","HPA053660"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7700","Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 14: REH - Unknown function","Single cell expression cluster":"Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB005884":"AB_443964","HPA053660":"AB_2682220"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.31e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.47e-12"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Tissue RNA - adipose tissue [nTPM]":"25.7","Tissue RNA - adrenal gland [nTPM]":"30.8","Tissue RNA - amygdala [nTPM]":"24.7","Tissue RNA - appendix [nTPM]":"23.5","Tissue RNA - basal ganglia [nTPM]":"25.8","Tissue RNA - bone marrow [nTPM]":"48.1","Tissue RNA - breast [nTPM]":"30.6","Tissue RNA - cerebellum [nTPM]":"26.5","Tissue RNA - cerebral cortex [nTPM]":"27.0","Tissue RNA - cervix [nTPM]":"33.1","Tissue RNA - choroid plexus [nTPM]":"20.4","Tissue RNA - colon [nTPM]":"31.6","Tissue RNA - duodenum [nTPM]":"26.4","Tissue RNA - endometrium 1 [nTPM]":"36.0","Tissue RNA - epididymis [nTPM]":"46.9","Tissue RNA - esophagus [nTPM]":"35.0","Tissue RNA - fallopian tube [nTPM]":"34.2","Tissue RNA - gallbladder [nTPM]":"25.3","Tissue RNA - heart muscle [nTPM]":"26.1","Tissue RNA - hippocampal formation [nTPM]":"25.3","Tissue RNA - hypothalamus [nTPM]":"28.2","Tissue RNA - kidney [nTPM]":"24.7","Tissue RNA - liver [nTPM]":"22.3","Tissue RNA - lung [nTPM]":"24.5","Tissue RNA - lymph node [nTPM]":"34.7","Tissue RNA - medulla oblongata [nTPM]":"19.8","Tissue RNA - midbrain [nTPM]":"22.0","Tissue RNA - ovary [nTPM]":"41.4","Tissue RNA - pancreas [nTPM]":"36.2","Tissue RNA - parathyroid gland [nTPM]":"51.2","Tissue RNA - pituitary gland [nTPM]":"41.5","Tissue RNA - placenta [nTPM]":"31.5","Tissue RNA - pons [nTPM]":"21.0","Tissue RNA - prostate [nTPM]":"32.2","Tissue RNA - rectum [nTPM]":"33.8","Tissue RNA - retina [nTPM]":"30.9","Tissue RNA - salivary gland [nTPM]":"36.6","Tissue RNA - seminal vesicle [nTPM]":"29.4","Tissue RNA - skeletal muscle [nTPM]":"47.3","Tissue RNA - skin 1 [nTPM]":"38.2","Tissue RNA - small intestine [nTPM]":"29.2","Tissue RNA - smooth muscle [nTPM]":"30.1","Tissue RNA - spinal cord [nTPM]":"21.2","Tissue RNA - spleen [nTPM]":"25.2","Tissue RNA - stomach 1 [nTPM]":"29.3","Tissue RNA - testis [nTPM]":"86.9","Tissue RNA - thalamus [nTPM]":"27.4","Tissue RNA - thymus [nTPM]":"55.8","Tissue RNA - thyroid gland [nTPM]":"28.5","Tissue RNA - tongue [nTPM]":"34.0","Tissue RNA - tonsil [nTPM]":"37.2","Tissue RNA - urinary bladder [nTPM]":"34.6","Tissue RNA - vagina [nTPM]":"31.5","Tissue RNA - white matter [nTPM]":"21.8","Cell RNA - A-431 [nTPM]":"128.1","Cell RNA - A549 [nTPM]":"64.7","Cell RNA - AF22 [nTPM]":"180.8","Cell RNA - AN3-CA [nTPM]":"160.7","Cell RNA - ASC diff [nTPM]":"47.0","Cell RNA - ASC TERT1 [nTPM]":"59.5","Cell RNA - BEWO [nTPM]":"128.4","Cell RNA - BJ [nTPM]":"53.1","Cell RNA - BJ hTERT+ [nTPM]":"66.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"106.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"93.7","Cell RNA - CACO-2 [nTPM]":"61.2","Cell RNA - CAPAN-2 [nTPM]":"120.5","Cell RNA - Daudi [nTPM]":"94.5","Cell RNA - EFO-21 [nTPM]":"74.1","Cell RNA - fHDF\/TERT166 [nTPM]":"87.6","Cell RNA - GAMG [nTPM]":"53.7","Cell RNA - HaCaT [nTPM]":"139.5","Cell RNA - HAP1 [nTPM]":"169.5","Cell RNA - HBEC3-KT [nTPM]":"101.0","Cell RNA - HBF TERT88 [nTPM]":"133.3","Cell RNA - HDLM-2 [nTPM]":"86.3","Cell RNA - HEK 293 [nTPM]":"102.7","Cell RNA - HEL [nTPM]":"133.0","Cell RNA - HeLa [nTPM]":"105.7","Cell RNA - Hep G2 [nTPM]":"150.6","Cell RNA - HHSteC [nTPM]":"59.6","Cell RNA - HL-60 [nTPM]":"103.7","Cell RNA - HMC-1 [nTPM]":"56.0","Cell RNA - HSkMC [nTPM]":"55.6","Cell RNA - hTCEpi [nTPM]":"71.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"112.8","Cell RNA - hTERT-HME1 [nTPM]":"78.9","Cell RNA - hTERT-RPE1 [nTPM]":"93.0","Cell RNA - HUVEC TERT2 [nTPM]":"134.1","Cell RNA - JURKAT [nTPM]":"171.7","Cell RNA - K-562 [nTPM]":"148.0","Cell RNA - Karpas-707 [nTPM]":"43.4","Cell RNA - LHCN-M2 [nTPM]":"76.3","Cell RNA - MCF7 [nTPM]":"75.9","Cell RNA - MOLT-4 [nTPM]":"227.3","Cell RNA - NB-4 [nTPM]":"79.2","Cell RNA - NTERA-2 [nTPM]":"118.3","Cell RNA - OE19 [nTPM]":"70.8","Cell RNA - PC-3 [nTPM]":"93.0","Cell RNA - REH [nTPM]":"214.7","Cell RNA - RH-30 [nTPM]":"119.1","Cell RNA - RPMI-8226 [nTPM]":"64.1","Cell RNA - RPTEC TERT1 [nTPM]":"89.0","Cell RNA - RT4 [nTPM]":"81.0","Cell RNA - SCLC-21H [nTPM]":"225.0","Cell RNA - SH-SY5Y [nTPM]":"169.9","Cell RNA - SiHa [nTPM]":"239.4","Cell RNA - SK-BR-3 [nTPM]":"62.4","Cell RNA - SK-MEL-30 [nTPM]":"80.2","Cell RNA - SuSa [nTPM]":"126.1","Cell RNA - T-47d [nTPM]":"62.7","Cell RNA - THP-1 [nTPM]":"76.2","Cell RNA - TIME [nTPM]":"109.5","Cell RNA - U-138 MG [nTPM]":"47.0","Cell RNA - U-2 OS [nTPM]":"78.4","Cell RNA - U-2197 [nTPM]":"88.1","Cell RNA - U-251 MG [nTPM]":"73.6","Cell RNA - U-266\/70 [nTPM]":"55.6","Cell RNA - U-266\/84 [nTPM]":"47.1","Cell RNA - U-698 [nTPM]":"109.3","Cell RNA - U-87 MG [nTPM]":"49.2","Cell RNA - U-937 [nTPM]":"120.4","Cell RNA - WM-115 [nTPM]":"68.3","Blood RNA - basophil [nTPM]":"2.0","Blood RNA - classical monocyte [nTPM]":"2.5","Blood RNA - eosinophil [nTPM]":"4.3","Blood RNA - gdT-cell [nTPM]":"4.1","Blood RNA - intermediate monocyte [nTPM]":"4.3","Blood RNA - MAIT T-cell [nTPM]":"3.4","Blood RNA - memory B-cell [nTPM]":"7.4","Blood RNA - memory CD4 T-cell [nTPM]":"3.5","Blood RNA - memory CD8 T-cell [nTPM]":"3.8","Blood RNA - myeloid DC [nTPM]":"3.1","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"4.5","Blood RNA - naive CD8 T-cell [nTPM]":"4.9","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"3.0","Blood RNA - non-classical monocyte [nTPM]":"5.5","Blood RNA - plasmacytoid DC [nTPM]":"6.8","Blood RNA - T-reg [nTPM]":"4.4","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"24.7","Brain RNA - basal ganglia [nTPM]":"25.8","Brain RNA - cerebellum [nTPM]":"26.5","Brain RNA - cerebral cortex [nTPM]":"27.0","Brain RNA - hippocampal formation [nTPM]":"25.3","Brain RNA - hypothalamus [nTPM]":"28.2","Brain RNA - medulla oblongata [nTPM]":"19.8","Brain RNA - midbrain [nTPM]":"22.0","Brain RNA - pons [nTPM]":"21.0","Brain RNA - spinal cord [nTPM]":"21.2","Brain RNA - thalamus [nTPM]":"27.4","Brain RNA - white matter [nTPM]":"21.8","Single Cell Type RNA - Adipocytes [nTPM]":"18.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.1","Single Cell Type RNA - Astrocytes [nTPM]":"33.6","Single Cell Type RNA - B-cells [nTPM]":"15.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"19.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"33.0","Single Cell Type RNA - Bipolar cells [nTPM]":"27.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"20.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"22.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"24.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"19.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"31.6","Single Cell Type RNA - dendritic cells [nTPM]":"18.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"35.4","Single Cell Type RNA - Early spermatids [nTPM]":"43.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"45.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"49.3","Single Cell Type RNA - Endothelial cells [nTPM]":"20.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.8","Single Cell Type RNA - Erythroid cells [nTPM]":"29.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"51.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"24.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"57.2","Single Cell Type RNA - Fibroblasts [nTPM]":"24.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"44.4","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"49.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.8","Single Cell Type RNA - Hepatocytes [nTPM]":"17.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.0","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"51.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.9","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"15.1","Single Cell Type RNA - Langerhans cells [nTPM]":"19.7","Single Cell Type RNA - Late spermatids [nTPM]":"20.3","Single Cell Type RNA - Leydig cells [nTPM]":"21.5","Single Cell Type RNA - Macrophages [nTPM]":"20.2","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"30.0","Single Cell Type RNA - monocytes [nTPM]":"28.1","Single Cell Type RNA - Muller glia cells [nTPM]":"19.3","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"50.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"30.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"28.1","Single Cell Type RNA - Paneth cells [nTPM]":"13.5","Single Cell Type RNA - Peritubular cells [nTPM]":"23.0","Single Cell Type RNA - Plasma cells [nTPM]":"28.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"26.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"25.0","Single Cell Type RNA - Spermatocytes [nTPM]":"131.8","Single Cell Type RNA - Spermatogonia [nTPM]":"67.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"36.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.6","Single Cell Type RNA - T-cells [nTPM]":"15.4","Single Cell Type RNA - Theca cells [nTPM]":"34.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"27.6","Single Cell Type RNA - Urothelial cells [nTPM]":"20.5"},{"Gene":"KDM3B","Gene synonym":["C5orf7","JMJD1B","KIAA1082","NET22"],"Ensembl":"ENSG00000120733","Gene description":"Lysine demethylase 3B","Uniprot":["Q7LBC6"],"Chromosome":"5","Position":"138352685-138437028","Protein class":["Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","Dioxygenase","Oxidoreductase"],"Disease involvement":["Disease variant","Dwarfism","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016610","HPA057202"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 65: Plasmacytoid DCs - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA016610":"AB_1852004","HPA057202":"AB_2683367"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.67e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-2"},"Tissue RNA - adipose tissue [nTPM]":"21.7","Tissue RNA - adrenal gland [nTPM]":"19.4","Tissue RNA - amygdala [nTPM]":"22.6","Tissue RNA - appendix [nTPM]":"16.9","Tissue RNA - basal ganglia [nTPM]":"23.0","Tissue RNA - bone marrow [nTPM]":"25.4","Tissue RNA - breast [nTPM]":"25.3","Tissue RNA - cerebellum [nTPM]":"22.2","Tissue RNA - cerebral cortex [nTPM]":"22.8","Tissue RNA - cervix [nTPM]":"22.7","Tissue RNA - choroid plexus [nTPM]":"21.1","Tissue RNA - colon [nTPM]":"23.9","Tissue RNA - duodenum [nTPM]":"18.6","Tissue RNA - endometrium 1 [nTPM]":"23.0","Tissue RNA - epididymis [nTPM]":"28.3","Tissue RNA - esophagus [nTPM]":"21.2","Tissue RNA - fallopian tube [nTPM]":"24.2","Tissue RNA - gallbladder [nTPM]":"14.2","Tissue RNA - heart muscle [nTPM]":"20.0","Tissue RNA - hippocampal formation [nTPM]":"21.3","Tissue RNA - hypothalamus [nTPM]":"20.7","Tissue RNA - kidney [nTPM]":"21.4","Tissue RNA - liver [nTPM]":"14.5","Tissue RNA - lung [nTPM]":"19.3","Tissue RNA - lymph node [nTPM]":"23.0","Tissue RNA - medulla oblongata [nTPM]":"23.4","Tissue RNA - midbrain [nTPM]":"22.7","Tissue RNA - ovary [nTPM]":"30.8","Tissue RNA - pancreas [nTPM]":"20.3","Tissue RNA - parathyroid gland [nTPM]":"34.2","Tissue RNA - pituitary gland [nTPM]":"16.5","Tissue RNA - placenta [nTPM]":"20.5","Tissue RNA - pons [nTPM]":"21.5","Tissue RNA - prostate [nTPM]":"21.8","Tissue RNA - rectum [nTPM]":"24.0","Tissue RNA - retina [nTPM]":"36.3","Tissue RNA - salivary gland [nTPM]":"22.2","Tissue RNA - seminal vesicle [nTPM]":"25.9","Tissue RNA - skeletal muscle [nTPM]":"41.5","Tissue RNA - skin 1 [nTPM]":"28.1","Tissue RNA - small intestine [nTPM]":"23.4","Tissue RNA - smooth muscle [nTPM]":"20.8","Tissue RNA - spinal cord [nTPM]":"21.9","Tissue RNA - spleen [nTPM]":"26.0","Tissue RNA - stomach 1 [nTPM]":"21.6","Tissue RNA - testis [nTPM]":"19.4","Tissue RNA - thalamus [nTPM]":"23.9","Tissue RNA - thymus [nTPM]":"35.9","Tissue RNA - thyroid gland [nTPM]":"23.2","Tissue RNA - tongue [nTPM]":"27.1","Tissue RNA - tonsil [nTPM]":"29.4","Tissue RNA - urinary bladder [nTPM]":"24.8","Tissue RNA - vagina [nTPM]":"19.9","Tissue RNA - white matter [nTPM]":"21.8","Cell RNA - A-431 [nTPM]":"24.3","Cell RNA - A549 [nTPM]":"32.4","Cell RNA - AF22 [nTPM]":"65.0","Cell RNA - AN3-CA [nTPM]":"58.7","Cell RNA - ASC diff [nTPM]":"27.2","Cell RNA - ASC TERT1 [nTPM]":"23.3","Cell RNA - BEWO [nTPM]":"47.0","Cell RNA - BJ [nTPM]":"15.6","Cell RNA - BJ hTERT+ [nTPM]":"27.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"30.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"33.5","Cell RNA - CACO-2 [nTPM]":"35.7","Cell RNA - CAPAN-2 [nTPM]":"27.2","Cell RNA - Daudi [nTPM]":"46.3","Cell RNA - EFO-21 [nTPM]":"27.9","Cell RNA - fHDF\/TERT166 [nTPM]":"30.3","Cell RNA - GAMG [nTPM]":"41.0","Cell RNA - HaCaT [nTPM]":"24.3","Cell RNA - HAP1 [nTPM]":"53.2","Cell RNA - HBEC3-KT [nTPM]":"37.8","Cell RNA - HBF TERT88 [nTPM]":"32.6","Cell RNA - HDLM-2 [nTPM]":"30.3","Cell RNA - HEK 293 [nTPM]":"29.3","Cell RNA - HEL [nTPM]":"39.2","Cell RNA - HeLa [nTPM]":"28.6","Cell RNA - Hep G2 [nTPM]":"27.1","Cell RNA - HHSteC [nTPM]":"25.4","Cell RNA - HL-60 [nTPM]":"32.2","Cell RNA - HMC-1 [nTPM]":"43.3","Cell RNA - HSkMC [nTPM]":"26.9","Cell RNA - hTCEpi [nTPM]":"39.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.1","Cell RNA - hTERT-HME1 [nTPM]":"26.7","Cell RNA - hTERT-RPE1 [nTPM]":"23.2","Cell RNA - HUVEC TERT2 [nTPM]":"34.6","Cell RNA - JURKAT [nTPM]":"29.3","Cell RNA - K-562 [nTPM]":"31.8","Cell RNA - Karpas-707 [nTPM]":"26.1","Cell RNA - LHCN-M2 [nTPM]":"34.3","Cell RNA - MCF7 [nTPM]":"30.3","Cell RNA - MOLT-4 [nTPM]":"46.4","Cell RNA - NB-4 [nTPM]":"41.0","Cell RNA - NTERA-2 [nTPM]":"31.0","Cell RNA - OE19 [nTPM]":"34.1","Cell RNA - PC-3 [nTPM]":"13.7","Cell RNA - REH [nTPM]":"53.1","Cell RNA - RH-30 [nTPM]":"48.5","Cell RNA - RPMI-8226 [nTPM]":"30.9","Cell RNA - RPTEC TERT1 [nTPM]":"40.4","Cell RNA - RT4 [nTPM]":"31.6","Cell RNA - SCLC-21H [nTPM]":"32.7","Cell RNA - SH-SY5Y [nTPM]":"35.9","Cell RNA - SiHa [nTPM]":"27.0","Cell RNA - SK-BR-3 [nTPM]":"28.0","Cell RNA - SK-MEL-30 [nTPM]":"25.7","Cell RNA - SuSa [nTPM]":"93.2","Cell RNA - T-47d [nTPM]":"27.3","Cell RNA - THP-1 [nTPM]":"43.5","Cell RNA - TIME [nTPM]":"31.9","Cell RNA - U-138 MG [nTPM]":"17.9","Cell RNA - U-2 OS [nTPM]":"17.4","Cell RNA - U-2197 [nTPM]":"19.3","Cell RNA - U-251 MG [nTPM]":"28.8","Cell RNA - U-266\/70 [nTPM]":"32.8","Cell RNA - U-266\/84 [nTPM]":"16.7","Cell RNA - U-698 [nTPM]":"40.2","Cell RNA - U-87 MG [nTPM]":"12.5","Cell RNA - U-937 [nTPM]":"45.6","Cell RNA - WM-115 [nTPM]":"25.6","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"2.9","Blood RNA - eosinophil [nTPM]":"4.2","Blood RNA - gdT-cell [nTPM]":"2.3","Blood RNA - intermediate monocyte [nTPM]":"2.2","Blood RNA - MAIT T-cell [nTPM]":"3.2","Blood RNA - memory B-cell [nTPM]":"2.3","Blood RNA - memory CD4 T-cell [nTPM]":"2.7","Blood RNA - memory CD8 T-cell [nTPM]":"3.0","Blood RNA - myeloid DC [nTPM]":"2.5","Blood RNA - naive B-cell [nTPM]":"2.0","Blood RNA - naive CD4 T-cell [nTPM]":"2.5","Blood RNA - naive CD8 T-cell [nTPM]":"2.3","Blood RNA - neutrophil [nTPM]":"5.5","Blood RNA - NK-cell [nTPM]":"4.2","Blood RNA - non-classical monocyte [nTPM]":"2.3","Blood RNA - plasmacytoid DC [nTPM]":"3.0","Blood RNA - T-reg [nTPM]":"1.7","Blood RNA - total PBMC [nTPM]":"1.3","Brain RNA - amygdala [nTPM]":"22.6","Brain RNA - basal ganglia [nTPM]":"23.0","Brain RNA - cerebellum [nTPM]":"22.2","Brain RNA - cerebral cortex [nTPM]":"22.8","Brain RNA - hippocampal formation [nTPM]":"21.3","Brain RNA - hypothalamus [nTPM]":"20.7","Brain RNA - medulla oblongata [nTPM]":"23.4","Brain RNA - midbrain [nTPM]":"22.7","Brain RNA - pons [nTPM]":"21.5","Brain RNA - spinal cord [nTPM]":"21.9","Brain RNA - thalamus [nTPM]":"23.9","Brain RNA - white matter [nTPM]":"21.8","Single Cell Type RNA - Adipocytes [nTPM]":"22.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.7","Single Cell Type RNA - Astrocytes [nTPM]":"43.1","Single Cell Type RNA - B-cells [nTPM]":"22.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"20.5","Single Cell Type RNA - Bipolar cells [nTPM]":"21.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"29.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"33.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"17.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.4","Single Cell Type RNA - dendritic cells [nTPM]":"24.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"26.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"16.0","Single Cell Type RNA - Early spermatids [nTPM]":"6.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.9","Single Cell Type RNA - Endothelial cells [nTPM]":"18.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.0","Single Cell Type RNA - Erythroid cells [nTPM]":"25.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"40.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.7","Single Cell Type RNA - Fibroblasts [nTPM]":"18.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.2","Single Cell Type RNA - granulocytes [nTPM]":"13.3","Single Cell Type RNA - Granulosa cells [nTPM]":"26.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.2","Single Cell Type RNA - Hepatocytes [nTPM]":"23.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.6","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"39.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.4","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"39.2","Single Cell Type RNA - Langerhans cells [nTPM]":"18.3","Single Cell Type RNA - Late spermatids [nTPM]":"2.8","Single Cell Type RNA - Leydig cells [nTPM]":"21.1","Single Cell Type RNA - Macrophages [nTPM]":"27.9","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"50.6","Single Cell Type RNA - monocytes [nTPM]":"27.0","Single Cell Type RNA - Muller glia cells [nTPM]":"17.3","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"41.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"56.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.9","Single Cell Type RNA - Paneth cells [nTPM]":"28.0","Single Cell Type RNA - Peritubular cells [nTPM]":"23.0","Single Cell Type RNA - Plasma cells [nTPM]":"16.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"21.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"25.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"31.9","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.7","Single Cell Type RNA - Spermatocytes [nTPM]":"13.0","Single Cell Type RNA - Spermatogonia [nTPM]":"15.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.9","Single Cell Type RNA - T-cells [nTPM]":"19.1","Single Cell Type RNA - Theca cells [nTPM]":"17.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.6","Single Cell Type RNA - Urothelial cells [nTPM]":"21.0"},{"Gene":"KDM5A","Gene synonym":["JARID1A","RBBP2"],"Ensembl":"ENSG00000073614","Gene description":"Lysine demethylase 5A","Uniprot":["P29375"],"Chromosome":"12","Position":"280057-389320","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins","Transcription factors"],"Biological process":["Biological rhythms","Transcription","Transcription regulation"],"Molecular function":["Activator","Chromatin regulator","Developmental protein","Dioxygenase","Oxidoreductase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"45.5"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006201"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 65: Plasmacytoid DCs - Unknown function","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA006201":"AB_1079160"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.69e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.1","Tissue RNA - adrenal gland [nTPM]":"8.7","Tissue RNA - amygdala [nTPM]":"5.8","Tissue RNA - appendix [nTPM]":"11.4","Tissue RNA - basal ganglia [nTPM]":"8.3","Tissue RNA - bone marrow [nTPM]":"45.5","Tissue RNA - breast [nTPM]":"11.1","Tissue RNA - cerebellum [nTPM]":"11.6","Tissue RNA - cerebral cortex [nTPM]":"8.5","Tissue RNA - cervix [nTPM]":"8.6","Tissue RNA - choroid plexus [nTPM]":"10.0","Tissue RNA - colon [nTPM]":"8.2","Tissue RNA - duodenum [nTPM]":"7.2","Tissue RNA - endometrium 1 [nTPM]":"9.7","Tissue RNA - epididymis [nTPM]":"7.1","Tissue RNA - esophagus [nTPM]":"8.9","Tissue RNA - fallopian tube [nTPM]":"7.6","Tissue RNA - gallbladder [nTPM]":"8.0","Tissue RNA - heart muscle [nTPM]":"5.2","Tissue RNA - hippocampal formation [nTPM]":"6.2","Tissue RNA - hypothalamus [nTPM]":"6.5","Tissue RNA - kidney [nTPM]":"7.8","Tissue RNA - liver [nTPM]":"9.9","Tissue RNA - lung [nTPM]":"8.8","Tissue RNA - lymph node [nTPM]":"15.3","Tissue RNA - medulla oblongata [nTPM]":"6.8","Tissue RNA - midbrain [nTPM]":"5.7","Tissue RNA - ovary [nTPM]":"11.0","Tissue RNA - pancreas [nTPM]":"9.4","Tissue RNA - parathyroid gland [nTPM]":"10.1","Tissue RNA - pituitary gland [nTPM]":"4.2","Tissue RNA - placenta [nTPM]":"11.8","Tissue RNA - pons [nTPM]":"6.5","Tissue RNA - prostate [nTPM]":"8.6","Tissue RNA - rectum [nTPM]":"9.9","Tissue RNA - retina [nTPM]":"9.6","Tissue RNA - salivary gland [nTPM]":"6.7","Tissue RNA - seminal vesicle [nTPM]":"7.3","Tissue RNA - skeletal muscle [nTPM]":"5.5","Tissue RNA - skin 1 [nTPM]":"12.5","Tissue RNA - small intestine [nTPM]":"7.3","Tissue RNA - smooth muscle [nTPM]":"9.4","Tissue RNA - spinal cord [nTPM]":"6.0","Tissue RNA - spleen [nTPM]":"13.5","Tissue RNA - stomach 1 [nTPM]":"8.8","Tissue RNA - testis [nTPM]":"21.1","Tissue RNA - thalamus [nTPM]":"6.7","Tissue RNA - thymus [nTPM]":"21.6","Tissue RNA - thyroid gland [nTPM]":"9.1","Tissue RNA - tongue [nTPM]":"7.6","Tissue RNA - tonsil [nTPM]":"14.4","Tissue RNA - urinary bladder [nTPM]":"8.7","Tissue RNA - vagina [nTPM]":"7.2","Tissue RNA - white matter [nTPM]":"15.0","Cell RNA - A-431 [nTPM]":"14.4","Cell RNA - A549 [nTPM]":"25.3","Cell RNA - AF22 [nTPM]":"18.3","Cell RNA - AN3-CA [nTPM]":"14.2","Cell RNA - ASC diff [nTPM]":"16.1","Cell RNA - ASC TERT1 [nTPM]":"15.2","Cell RNA - BEWO [nTPM]":"20.3","Cell RNA - BJ [nTPM]":"12.5","Cell RNA - BJ hTERT+ [nTPM]":"16.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.8","Cell RNA - CACO-2 [nTPM]":"15.2","Cell RNA - CAPAN-2 [nTPM]":"17.0","Cell RNA - Daudi [nTPM]":"24.0","Cell RNA - EFO-21 [nTPM]":"3.9","Cell RNA - fHDF\/TERT166 [nTPM]":"21.0","Cell RNA - GAMG [nTPM]":"16.0","Cell RNA - HaCaT [nTPM]":"13.3","Cell RNA - HAP1 [nTPM]":"19.2","Cell RNA - HBEC3-KT [nTPM]":"14.2","Cell RNA - HBF TERT88 [nTPM]":"21.9","Cell RNA - HDLM-2 [nTPM]":"37.9","Cell RNA - HEK 293 [nTPM]":"15.9","Cell RNA - HEL [nTPM]":"29.3","Cell RNA - HeLa [nTPM]":"26.5","Cell RNA - Hep G2 [nTPM]":"9.0","Cell RNA - HHSteC [nTPM]":"13.0","Cell RNA - HL-60 [nTPM]":"38.6","Cell RNA - HMC-1 [nTPM]":"22.1","Cell RNA - HSkMC [nTPM]":"16.6","Cell RNA - hTCEpi [nTPM]":"13.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.6","Cell RNA - hTERT-HME1 [nTPM]":"29.9","Cell RNA - hTERT-RPE1 [nTPM]":"18.8","Cell RNA - HUVEC TERT2 [nTPM]":"18.8","Cell RNA - JURKAT [nTPM]":"21.0","Cell RNA - K-562 [nTPM]":"17.9","Cell RNA - Karpas-707 [nTPM]":"32.7","Cell RNA - LHCN-M2 [nTPM]":"15.7","Cell RNA - MCF7 [nTPM]":"9.7","Cell RNA - MOLT-4 [nTPM]":"27.9","Cell RNA - NB-4 [nTPM]":"11.0","Cell RNA - NTERA-2 [nTPM]":"28.4","Cell RNA - OE19 [nTPM]":"12.3","Cell RNA - PC-3 [nTPM]":"7.9","Cell RNA - REH [nTPM]":"25.7","Cell RNA - RH-30 [nTPM]":"47.5","Cell RNA - RPMI-8226 [nTPM]":"11.4","Cell RNA - RPTEC TERT1 [nTPM]":"8.8","Cell RNA - RT4 [nTPM]":"32.6","Cell RNA - SCLC-21H [nTPM]":"7.0","Cell RNA - SH-SY5Y [nTPM]":"20.5","Cell RNA - SiHa [nTPM]":"24.5","Cell RNA - SK-BR-3 [nTPM]":"11.0","Cell RNA - SK-MEL-30 [nTPM]":"13.0","Cell RNA - SuSa [nTPM]":"25.0","Cell RNA - T-47d [nTPM]":"11.9","Cell RNA - THP-1 [nTPM]":"24.0","Cell RNA - TIME [nTPM]":"26.0","Cell RNA - U-138 MG [nTPM]":"12.0","Cell RNA - U-2 OS [nTPM]":"17.0","Cell RNA - U-2197 [nTPM]":"13.6","Cell RNA - U-251 MG [nTPM]":"21.1","Cell RNA - U-266\/70 [nTPM]":"11.5","Cell RNA - U-266\/84 [nTPM]":"13.6","Cell RNA - U-698 [nTPM]":"53.7","Cell RNA - U-87 MG [nTPM]":"15.5","Cell RNA - U-937 [nTPM]":"16.5","Cell RNA - WM-115 [nTPM]":"18.0","Blood RNA - basophil [nTPM]":"64.5","Blood RNA - classical monocyte [nTPM]":"21.8","Blood RNA - eosinophil [nTPM]":"44.4","Blood RNA - gdT-cell [nTPM]":"31.4","Blood RNA - intermediate monocyte [nTPM]":"25.0","Blood RNA - MAIT T-cell [nTPM]":"32.3","Blood RNA - memory B-cell [nTPM]":"27.1","Blood RNA - memory CD4 T-cell [nTPM]":"24.6","Blood RNA - memory CD8 T-cell [nTPM]":"25.9","Blood RNA - myeloid DC [nTPM]":"22.8","Blood RNA - naive B-cell [nTPM]":"32.0","Blood RNA - naive CD4 T-cell [nTPM]":"26.3","Blood RNA - naive CD8 T-cell [nTPM]":"22.8","Blood RNA - neutrophil [nTPM]":"63.0","Blood RNA - NK-cell [nTPM]":"35.8","Blood RNA - non-classical monocyte [nTPM]":"28.9","Blood RNA - plasmacytoid DC [nTPM]":"32.0","Blood RNA - T-reg [nTPM]":"20.9","Blood RNA - total PBMC [nTPM]":"22.5","Brain RNA - amygdala [nTPM]":"5.8","Brain RNA - basal ganglia [nTPM]":"8.3","Brain RNA - cerebellum [nTPM]":"11.6","Brain RNA - cerebral cortex [nTPM]":"8.5","Brain RNA - hippocampal formation [nTPM]":"6.2","Brain RNA - hypothalamus [nTPM]":"6.5","Brain RNA - medulla oblongata [nTPM]":"6.8","Brain RNA - midbrain [nTPM]":"5.7","Brain RNA - pons [nTPM]":"6.5","Brain RNA - spinal cord [nTPM]":"6.0","Brain RNA - thalamus [nTPM]":"6.7","Brain RNA - white matter [nTPM]":"15.0","Single Cell Type RNA - Adipocytes [nTPM]":"53.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"64.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"61.6","Single Cell Type RNA - Astrocytes [nTPM]":"61.7","Single Cell Type RNA - B-cells [nTPM]":"80.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"33.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"48.9","Single Cell Type RNA - Bipolar cells [nTPM]":"69.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"35.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"27.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"38.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"31.5","Single Cell Type RNA - Club cells [nTPM]":"39.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"35.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"116.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"48.8","Single Cell Type RNA - dendritic cells [nTPM]":"103.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"51.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"37.4","Single Cell Type RNA - Early spermatids [nTPM]":"96.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"60.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"72.8","Single Cell Type RNA - Endothelial cells [nTPM]":"51.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"69.7","Single Cell Type RNA - Erythroid cells [nTPM]":"51.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"71.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"31.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"34.7","Single Cell Type RNA - Fibroblasts [nTPM]":"47.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"39.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"99.8","Single Cell Type RNA - granulocytes [nTPM]":"54.4","Single Cell Type RNA - Granulosa cells [nTPM]":"106.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"42.8","Single Cell Type RNA - Hepatocytes [nTPM]":"30.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.2","Single Cell Type RNA - Horizontal cells [nTPM]":"87.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"59.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"40.0","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"52.5","Single Cell Type RNA - Langerhans cells [nTPM]":"37.5","Single Cell Type RNA - Late spermatids [nTPM]":"32.5","Single Cell Type RNA - Leydig cells [nTPM]":"48.4","Single Cell Type RNA - Macrophages [nTPM]":"63.9","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"57.1","Single Cell Type RNA - monocytes [nTPM]":"82.9","Single Cell Type RNA - Muller glia cells [nTPM]":"48.3","Single Cell Type RNA - NK-cells [nTPM]":"105.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"68.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"85.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"38.7","Single Cell Type RNA - Paneth cells [nTPM]":"37.0","Single Cell Type RNA - Peritubular cells [nTPM]":"55.7","Single Cell Type RNA - Plasma cells [nTPM]":"73.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"32.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"33.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"40.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"71.9","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"64.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"59.9","Single Cell Type RNA - Spermatocytes [nTPM]":"137.1","Single Cell Type RNA - Spermatogonia [nTPM]":"104.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"50.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"47.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"71.1","Single Cell Type RNA - T-cells [nTPM]":"80.1","Single Cell Type RNA - Theca cells [nTPM]":"67.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"40.1","Single Cell Type RNA - Urothelial cells [nTPM]":"42.0"},{"Gene":"KDM5B","Gene synonym":["CT31","JARID1B","PLU-1","PPP1R98","RBBP2H1A"],"Ensembl":"ENSG00000117139","Gene description":"Lysine demethylase 5B","Uniprot":["Q9UGL1"],"Chromosome":"1","Position":"202724495-202808487","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transcription factors"],"Biological process":["Biological rhythms","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","Dioxygenase","Oxidoreductase","Repressor"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"62.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"243.6","Spermatocytes":"390.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027179","HPA053723","CAB068193"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB068193":"AB_2665696","HPA027179":"AB_1851987","HPA053723":"AB_2682241"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.1","Tissue RNA - adrenal gland [nTPM]":"7.7","Tissue RNA - amygdala [nTPM]":"1.5","Tissue RNA - appendix [nTPM]":"2.6","Tissue RNA - basal ganglia [nTPM]":"2.2","Tissue RNA - bone marrow [nTPM]":"14.1","Tissue RNA - breast [nTPM]":"9.9","Tissue RNA - cerebellum [nTPM]":"5.8","Tissue RNA - cerebral cortex [nTPM]":"4.8","Tissue RNA - cervix [nTPM]":"14.7","Tissue RNA - choroid plexus [nTPM]":"7.9","Tissue RNA - colon [nTPM]":"10.6","Tissue RNA - duodenum [nTPM]":"2.1","Tissue RNA - endometrium 1 [nTPM]":"12.6","Tissue RNA - epididymis [nTPM]":"3.3","Tissue RNA - esophagus [nTPM]":"21.0","Tissue RNA - fallopian tube [nTPM]":"9.9","Tissue RNA - gallbladder [nTPM]":"2.9","Tissue RNA - heart muscle [nTPM]":"6.0","Tissue RNA - hippocampal formation [nTPM]":"4.6","Tissue RNA - hypothalamus [nTPM]":"1.5","Tissue RNA - kidney [nTPM]":"6.2","Tissue RNA - liver [nTPM]":"4.6","Tissue RNA - lung [nTPM]":"10.8","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"0.8","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"12.8","Tissue RNA - pancreas [nTPM]":"8.3","Tissue RNA - parathyroid gland [nTPM]":"2.6","Tissue RNA - pituitary gland [nTPM]":"6.9","Tissue RNA - placenta [nTPM]":"4.7","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"10.6","Tissue RNA - rectum [nTPM]":"2.2","Tissue RNA - retina [nTPM]":"17.8","Tissue RNA - salivary gland [nTPM]":"12.5","Tissue RNA - seminal vesicle [nTPM]":"2.4","Tissue RNA - skeletal muscle [nTPM]":"4.7","Tissue RNA - skin 1 [nTPM]":"24.3","Tissue RNA - small intestine [nTPM]":"8.6","Tissue RNA - smooth muscle [nTPM]":"3.1","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"7.4","Tissue RNA - stomach 1 [nTPM]":"8.7","Tissue RNA - testis [nTPM]":"62.3","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"4.1","Tissue RNA - thyroid gland [nTPM]":"8.4","Tissue RNA - tongue [nTPM]":"0.8","Tissue RNA - tonsil [nTPM]":"2.1","Tissue RNA - urinary bladder [nTPM]":"10.9","Tissue RNA - vagina [nTPM]":"15.7","Tissue RNA - white matter [nTPM]":"2.3","Cell RNA - A-431 [nTPM]":"9.9","Cell RNA - A549 [nTPM]":"2.4","Cell RNA - AF22 [nTPM]":"14.0","Cell RNA - AN3-CA [nTPM]":"9.8","Cell RNA - ASC diff [nTPM]":"7.2","Cell RNA - ASC TERT1 [nTPM]":"6.6","Cell RNA - BEWO [nTPM]":"23.7","Cell RNA - BJ [nTPM]":"6.2","Cell RNA - BJ hTERT+ [nTPM]":"9.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.4","Cell RNA - CACO-2 [nTPM]":"2.2","Cell RNA - CAPAN-2 [nTPM]":"8.8","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"5.7","Cell RNA - fHDF\/TERT166 [nTPM]":"7.9","Cell RNA - GAMG [nTPM]":"2.3","Cell RNA - HaCaT [nTPM]":"11.8","Cell RNA - HAP1 [nTPM]":"9.0","Cell RNA - HBEC3-KT [nTPM]":"8.3","Cell RNA - HBF TERT88 [nTPM]":"5.4","Cell RNA - HDLM-2 [nTPM]":"0.5","Cell RNA - HEK 293 [nTPM]":"12.8","Cell RNA - HEL [nTPM]":"7.7","Cell RNA - HeLa [nTPM]":"2.4","Cell RNA - Hep G2 [nTPM]":"1.9","Cell RNA - HHSteC [nTPM]":"5.5","Cell RNA - HL-60 [nTPM]":"17.7","Cell RNA - HMC-1 [nTPM]":"8.9","Cell RNA - HSkMC [nTPM]":"9.4","Cell RNA - hTCEpi [nTPM]":"12.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.0","Cell RNA - hTERT-HME1 [nTPM]":"7.2","Cell RNA - hTERT-RPE1 [nTPM]":"10.1","Cell RNA - HUVEC TERT2 [nTPM]":"11.7","Cell RNA - JURKAT [nTPM]":"7.3","Cell RNA - K-562 [nTPM]":"20.9","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"4.9","Cell RNA - MCF7 [nTPM]":"6.3","Cell RNA - MOLT-4 [nTPM]":"5.8","Cell RNA - NB-4 [nTPM]":"16.4","Cell RNA - NTERA-2 [nTPM]":"21.9","Cell RNA - OE19 [nTPM]":"4.3","Cell RNA - PC-3 [nTPM]":"28.0","Cell RNA - REH [nTPM]":"18.7","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"6.5","Cell RNA - RT4 [nTPM]":"10.7","Cell RNA - SCLC-21H [nTPM]":"10.7","Cell RNA - SH-SY5Y [nTPM]":"23.4","Cell RNA - SiHa [nTPM]":"14.7","Cell RNA - SK-BR-3 [nTPM]":"7.9","Cell RNA - SK-MEL-30 [nTPM]":"8.7","Cell RNA - SuSa [nTPM]":"15.7","Cell RNA - T-47d [nTPM]":"16.6","Cell RNA - THP-1 [nTPM]":"10.5","Cell RNA - TIME [nTPM]":"12.8","Cell RNA - U-138 MG [nTPM]":"8.2","Cell RNA - U-2 OS [nTPM]":"5.8","Cell RNA - U-2197 [nTPM]":"1.4","Cell RNA - U-251 MG [nTPM]":"5.2","Cell RNA - U-266\/70 [nTPM]":"2.3","Cell RNA - U-266\/84 [nTPM]":"1.1","Cell RNA - U-698 [nTPM]":"8.2","Cell RNA - U-87 MG [nTPM]":"6.0","Cell RNA - U-937 [nTPM]":"5.5","Cell RNA - WM-115 [nTPM]":"4.1","Blood RNA - basophil [nTPM]":"44.6","Blood RNA - classical monocyte [nTPM]":"6.4","Blood RNA - eosinophil [nTPM]":"19.6","Blood RNA - gdT-cell [nTPM]":"7.7","Blood RNA - intermediate monocyte [nTPM]":"4.8","Blood RNA - MAIT T-cell [nTPM]":"4.6","Blood RNA - memory B-cell [nTPM]":"10.9","Blood RNA - memory CD4 T-cell [nTPM]":"8.9","Blood RNA - memory CD8 T-cell [nTPM]":"4.3","Blood RNA - myeloid DC [nTPM]":"4.2","Blood RNA - naive B-cell [nTPM]":"17.4","Blood RNA - naive CD4 T-cell [nTPM]":"9.6","Blood RNA - naive CD8 T-cell [nTPM]":"6.0","Blood RNA - neutrophil [nTPM]":"34.4","Blood RNA - NK-cell [nTPM]":"12.9","Blood RNA - non-classical monocyte [nTPM]":"10.4","Blood RNA - plasmacytoid DC [nTPM]":"6.6","Blood RNA - T-reg [nTPM]":"7.2","Blood RNA - total PBMC [nTPM]":"3.9","Brain RNA - amygdala [nTPM]":"1.5","Brain RNA - basal ganglia [nTPM]":"2.2","Brain RNA - cerebellum [nTPM]":"5.8","Brain RNA - cerebral cortex [nTPM]":"4.8","Brain RNA - hippocampal formation [nTPM]":"4.6","Brain RNA - hypothalamus [nTPM]":"1.5","Brain RNA - medulla oblongata [nTPM]":"0.8","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"2.3","Single Cell Type RNA - Adipocytes [nTPM]":"24.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"89.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"38.5","Single Cell Type RNA - Astrocytes [nTPM]":"46.7","Single Cell Type RNA - B-cells [nTPM]":"22.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"64.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"34.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"53.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"84.2","Single Cell Type RNA - Bipolar cells [nTPM]":"35.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"57.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"50.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"53.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"62.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"41.8","Single Cell Type RNA - dendritic cells [nTPM]":"12.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"47.6","Single Cell Type RNA - Early spermatids [nTPM]":"191.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"65.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"71.8","Single Cell Type RNA - Endothelial cells [nTPM]":"31.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"43.6","Single Cell Type RNA - Erythroid cells [nTPM]":"50.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"75.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"22.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"34.3","Single Cell Type RNA - Fibroblasts [nTPM]":"42.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"47.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"69.5","Single Cell Type RNA - granulocytes [nTPM]":"27.1","Single Cell Type RNA - Granulosa cells [nTPM]":"28.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.2","Single Cell Type RNA - Hepatocytes [nTPM]":"10.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.7","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"53.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"38.1","Single Cell Type RNA - Ionocytes [nTPM]":"44.7","Single Cell Type RNA - Kupffer cells [nTPM]":"15.1","Single Cell Type RNA - Langerhans cells [nTPM]":"21.9","Single Cell Type RNA - Late spermatids [nTPM]":"243.6","Single Cell Type RNA - Leydig cells [nTPM]":"36.4","Single Cell Type RNA - Macrophages [nTPM]":"15.5","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"40.3","Single Cell Type RNA - monocytes [nTPM]":"11.3","Single Cell Type RNA - Muller glia cells [nTPM]":"69.8","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"39.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"42.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"45.4","Single Cell Type RNA - Paneth cells [nTPM]":"21.8","Single Cell Type RNA - Peritubular cells [nTPM]":"32.7","Single Cell Type RNA - Plasma cells [nTPM]":"25.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"43.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"61.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"138.6","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"40.2","Single Cell Type RNA - Spermatocytes [nTPM]":"390.9","Single Cell Type RNA - Spermatogonia [nTPM]":"71.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"95.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"116.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"82.4","Single Cell Type RNA - T-cells [nTPM]":"21.2","Single Cell Type RNA - Theca cells [nTPM]":"61.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"30.2","Single Cell Type RNA - Urothelial cells [nTPM]":"55.6"},{"Gene":"KDM5C","Gene synonym":["DXS1272E","JARID1C","MRX13","SMCX","XE169"],"Ensembl":"ENSG00000126012","Gene description":"Lysine demethylase 5C","Uniprot":["P41229"],"Chromosome":"X","Position":"53191321-53225422","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transcription factors"],"Biological process":["Biological rhythms","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","Dioxygenase","Oxidoreductase","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038244","HPA046147"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA038244":"AB_2675911","HPA046147":"AB_2679555"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.11e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Tissue RNA - adipose tissue [nTPM]":"22.3","Tissue RNA - adrenal gland [nTPM]":"29.0","Tissue RNA - amygdala [nTPM]":"19.2","Tissue RNA - appendix [nTPM]":"28.2","Tissue RNA - basal ganglia [nTPM]":"19.7","Tissue RNA - bone marrow [nTPM]":"34.8","Tissue RNA - breast [nTPM]":"22.7","Tissue RNA - cerebellum [nTPM]":"23.0","Tissue RNA - cerebral cortex [nTPM]":"21.7","Tissue RNA - cervix [nTPM]":"35.5","Tissue RNA - choroid plexus [nTPM]":"22.2","Tissue RNA - colon [nTPM]":"25.5","Tissue RNA - duodenum [nTPM]":"26.0","Tissue RNA - endometrium 1 [nTPM]":"35.5","Tissue RNA - epididymis [nTPM]":"14.8","Tissue RNA - esophagus [nTPM]":"35.2","Tissue RNA - fallopian tube [nTPM]":"33.2","Tissue RNA - gallbladder [nTPM]":"17.1","Tissue RNA - heart muscle [nTPM]":"22.7","Tissue RNA - hippocampal formation [nTPM]":"19.6","Tissue RNA - hypothalamus [nTPM]":"20.1","Tissue RNA - kidney [nTPM]":"21.1","Tissue RNA - liver [nTPM]":"24.1","Tissue RNA - lung [nTPM]":"27.2","Tissue RNA - lymph node [nTPM]":"33.4","Tissue RNA - medulla oblongata [nTPM]":"19.8","Tissue RNA - midbrain [nTPM]":"19.0","Tissue RNA - ovary [nTPM]":"39.9","Tissue RNA - pancreas [nTPM]":"26.4","Tissue RNA - parathyroid gland [nTPM]":"33.8","Tissue RNA - pituitary gland [nTPM]":"31.4","Tissue RNA - placenta [nTPM]":"23.8","Tissue RNA - pons [nTPM]":"19.0","Tissue RNA - prostate [nTPM]":"23.8","Tissue RNA - rectum [nTPM]":"15.4","Tissue RNA - retina [nTPM]":"24.6","Tissue RNA - salivary gland [nTPM]":"29.4","Tissue RNA - seminal vesicle [nTPM]":"18.5","Tissue RNA - skeletal muscle [nTPM]":"51.0","Tissue RNA - skin 1 [nTPM]":"34.2","Tissue RNA - small intestine [nTPM]":"28.2","Tissue RNA - smooth muscle [nTPM]":"26.9","Tissue RNA - spinal cord [nTPM]":"16.8","Tissue RNA - spleen [nTPM]":"30.9","Tissue RNA - stomach 1 [nTPM]":"25.8","Tissue RNA - testis [nTPM]":"13.5","Tissue RNA - thalamus [nTPM]":"20.9","Tissue RNA - thymus [nTPM]":"44.2","Tissue RNA - thyroid gland [nTPM]":"27.6","Tissue RNA - tongue [nTPM]":"25.5","Tissue RNA - tonsil [nTPM]":"26.5","Tissue RNA - urinary bladder [nTPM]":"25.9","Tissue RNA - vagina [nTPM]":"35.4","Tissue RNA - white matter [nTPM]":"20.8","Cell RNA - A-431 [nTPM]":"45.3","Cell RNA - A549 [nTPM]":"60.4","Cell RNA - AF22 [nTPM]":"63.6","Cell RNA - AN3-CA [nTPM]":"49.0","Cell RNA - ASC diff [nTPM]":"43.2","Cell RNA - ASC TERT1 [nTPM]":"39.1","Cell RNA - BEWO [nTPM]":"45.2","Cell RNA - BJ [nTPM]":"27.7","Cell RNA - BJ hTERT+ [nTPM]":"32.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"36.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"34.0","Cell RNA - CACO-2 [nTPM]":"41.3","Cell RNA - CAPAN-2 [nTPM]":"28.9","Cell RNA - Daudi [nTPM]":"41.8","Cell RNA - EFO-21 [nTPM]":"35.0","Cell RNA - fHDF\/TERT166 [nTPM]":"36.7","Cell RNA - GAMG [nTPM]":"103.2","Cell RNA - HaCaT [nTPM]":"39.5","Cell RNA - HAP1 [nTPM]":"72.6","Cell RNA - HBEC3-KT [nTPM]":"59.1","Cell RNA - HBF TERT88 [nTPM]":"27.8","Cell RNA - HDLM-2 [nTPM]":"31.6","Cell RNA - HEK 293 [nTPM]":"107.9","Cell RNA - HEL [nTPM]":"40.6","Cell RNA - HeLa [nTPM]":"66.7","Cell RNA - Hep G2 [nTPM]":"29.6","Cell RNA - HHSteC [nTPM]":"52.9","Cell RNA - HL-60 [nTPM]":"48.5","Cell RNA - HMC-1 [nTPM]":"77.6","Cell RNA - HSkMC [nTPM]":"31.0","Cell RNA - hTCEpi [nTPM]":"42.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"72.0","Cell RNA - hTERT-HME1 [nTPM]":"87.7","Cell RNA - hTERT-RPE1 [nTPM]":"52.3","Cell RNA - HUVEC TERT2 [nTPM]":"55.2","Cell RNA - JURKAT [nTPM]":"34.2","Cell RNA - K-562 [nTPM]":"80.8","Cell RNA - Karpas-707 [nTPM]":"27.2","Cell RNA - LHCN-M2 [nTPM]":"27.3","Cell RNA - MCF7 [nTPM]":"57.9","Cell RNA - MOLT-4 [nTPM]":"35.9","Cell RNA - NB-4 [nTPM]":"55.4","Cell RNA - NTERA-2 [nTPM]":"54.1","Cell RNA - OE19 [nTPM]":"23.3","Cell RNA - PC-3 [nTPM]":"56.3","Cell RNA - REH [nTPM]":"40.1","Cell RNA - RH-30 [nTPM]":"37.8","Cell RNA - RPMI-8226 [nTPM]":"45.9","Cell RNA - RPTEC TERT1 [nTPM]":"23.5","Cell RNA - RT4 [nTPM]":"42.6","Cell RNA - SCLC-21H [nTPM]":"47.6","Cell RNA - SH-SY5Y [nTPM]":"61.4","Cell RNA - SiHa [nTPM]":"84.0","Cell RNA - SK-BR-3 [nTPM]":"76.8","Cell RNA - SK-MEL-30 [nTPM]":"32.2","Cell RNA - SuSa [nTPM]":"58.4","Cell RNA - T-47d [nTPM]":"53.9","Cell RNA - THP-1 [nTPM]":"42.3","Cell RNA - TIME [nTPM]":"37.8","Cell RNA - U-138 MG [nTPM]":"40.6","Cell RNA - U-2 OS [nTPM]":"35.0","Cell RNA - U-2197 [nTPM]":"36.9","Cell RNA - U-251 MG [nTPM]":"27.2","Cell RNA - U-266\/70 [nTPM]":"39.0","Cell RNA - U-266\/84 [nTPM]":"34.2","Cell RNA - U-698 [nTPM]":"31.5","Cell RNA - U-87 MG [nTPM]":"52.6","Cell RNA - U-937 [nTPM]":"56.9","Cell RNA - WM-115 [nTPM]":"30.8","Blood RNA - basophil [nTPM]":"0.9","Blood RNA - classical monocyte [nTPM]":"1.2","Blood RNA - eosinophil [nTPM]":"0.8","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"1.4","Blood RNA - memory B-cell [nTPM]":"1.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.0","Blood RNA - memory CD8 T-cell [nTPM]":"1.6","Blood RNA - myeloid DC [nTPM]":"0.9","Blood RNA - naive B-cell [nTPM]":"0.8","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.8","Blood RNA - neutrophil [nTPM]":"1.4","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"1.2","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"1.3","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"19.2","Brain RNA - basal ganglia [nTPM]":"19.7","Brain RNA - cerebellum [nTPM]":"23.0","Brain RNA - cerebral cortex [nTPM]":"21.7","Brain RNA - hippocampal formation [nTPM]":"19.6","Brain RNA - hypothalamus [nTPM]":"20.1","Brain RNA - medulla oblongata [nTPM]":"19.8","Brain RNA - midbrain [nTPM]":"19.0","Brain RNA - pons [nTPM]":"19.0","Brain RNA - spinal cord [nTPM]":"16.8","Brain RNA - thalamus [nTPM]":"20.9","Brain RNA - white matter [nTPM]":"20.8","Single Cell Type RNA - Adipocytes [nTPM]":"17.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.9","Single Cell Type RNA - Astrocytes [nTPM]":"33.0","Single Cell Type RNA - B-cells [nTPM]":"17.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"24.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"15.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.1","Single Cell Type RNA - dendritic cells [nTPM]":"21.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"32.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"15.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"28.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"25.2","Single Cell Type RNA - Endothelial cells [nTPM]":"17.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"31.2","Single Cell Type RNA - Erythroid cells [nTPM]":"17.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"36.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.1","Single Cell Type RNA - Fibroblasts [nTPM]":"14.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"35.7","Single Cell Type RNA - granulocytes [nTPM]":"13.3","Single Cell Type RNA - Granulosa cells [nTPM]":"25.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.0","Single Cell Type RNA - Hepatocytes [nTPM]":"25.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.4","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"25.8","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"18.2","Single Cell Type RNA - Langerhans cells [nTPM]":"8.8","Single Cell Type RNA - Late spermatids [nTPM]":"2.6","Single Cell Type RNA - Leydig cells [nTPM]":"14.6","Single Cell Type RNA - Macrophages [nTPM]":"17.1","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"27.2","Single Cell Type RNA - monocytes [nTPM]":"14.9","Single Cell Type RNA - Muller glia cells [nTPM]":"9.8","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"31.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"49.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"26.4","Single Cell Type RNA - Paneth cells [nTPM]":"26.3","Single Cell Type RNA - Peritubular cells [nTPM]":"15.8","Single Cell Type RNA - Plasma cells [nTPM]":"17.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.8","Single Cell Type RNA - Spermatocytes [nTPM]":"10.3","Single Cell Type RNA - Spermatogonia [nTPM]":"15.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.8","Single Cell Type RNA - T-cells [nTPM]":"18.0","Single Cell Type RNA - Theca cells [nTPM]":"22.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.9","Single Cell Type RNA - Urothelial cells [nTPM]":"21.6"},{"Gene":"KDM6A","Gene synonym":["UTX"],"Ensembl":"ENSG00000147050","Gene description":"Lysine demethylase 6A","Uniprot":["O15550"],"Chromosome":"X","Position":"44873188-45112779","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Chromatin regulator","Dioxygenase","Oxidoreductase"],"Disease involvement":["Cancer-related genes","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Microglial cells":"116.2","Oligodendrocyte precursor cells":"118.1","Oligodendrocytes":"264.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000568","HPA001165","HPA002111"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Nucleoli rim"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoli","Nucleoli rim"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA000568":"AB_1858705","HPA001165":"AB_1080541","HPA002111":"AB_1858704"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.6","Tissue RNA - adrenal gland [nTPM]":"8.0","Tissue RNA - amygdala [nTPM]":"6.7","Tissue RNA - appendix [nTPM]":"4.5","Tissue RNA - basal ganglia [nTPM]":"7.6","Tissue RNA - bone marrow [nTPM]":"19.4","Tissue RNA - breast [nTPM]":"10.6","Tissue RNA - cerebellum [nTPM]":"7.2","Tissue RNA - cerebral cortex [nTPM]":"10.6","Tissue RNA - cervix [nTPM]":"15.7","Tissue RNA - choroid plexus [nTPM]":"6.5","Tissue RNA - colon [nTPM]":"9.1","Tissue RNA - duodenum [nTPM]":"6.2","Tissue RNA - endometrium 1 [nTPM]":"14.0","Tissue RNA - epididymis [nTPM]":"5.1","Tissue RNA - esophagus [nTPM]":"11.1","Tissue RNA - fallopian tube [nTPM]":"14.0","Tissue RNA - gallbladder [nTPM]":"3.4","Tissue RNA - heart muscle [nTPM]":"6.6","Tissue RNA - hippocampal formation [nTPM]":"6.8","Tissue RNA - hypothalamus [nTPM]":"6.9","Tissue RNA - kidney [nTPM]":"6.8","Tissue RNA - liver [nTPM]":"10.4","Tissue RNA - lung [nTPM]":"10.8","Tissue RNA - lymph node [nTPM]":"8.0","Tissue RNA - medulla oblongata [nTPM]":"7.3","Tissue RNA - midbrain [nTPM]":"6.8","Tissue RNA - ovary [nTPM]":"17.2","Tissue RNA - pancreas [nTPM]":"10.8","Tissue RNA - parathyroid gland [nTPM]":"6.4","Tissue RNA - pituitary gland [nTPM]":"8.6","Tissue RNA - placenta [nTPM]":"3.9","Tissue RNA - pons [nTPM]":"7.3","Tissue RNA - prostate [nTPM]":"7.7","Tissue RNA - rectum [nTPM]":"4.1","Tissue RNA - retina [nTPM]":"3.8","Tissue RNA - salivary gland [nTPM]":"10.5","Tissue RNA - seminal vesicle [nTPM]":"3.1","Tissue RNA - skeletal muscle [nTPM]":"10.4","Tissue RNA - skin 1 [nTPM]":"18.4","Tissue RNA - small intestine [nTPM]":"13.0","Tissue RNA - smooth muscle [nTPM]":"4.1","Tissue RNA - spinal cord [nTPM]":"7.1","Tissue RNA - spleen [nTPM]":"14.1","Tissue RNA - stomach 1 [nTPM]":"12.5","Tissue RNA - testis [nTPM]":"12.2","Tissue RNA - thalamus [nTPM]":"7.0","Tissue RNA - thymus [nTPM]":"12.9","Tissue RNA - thyroid gland [nTPM]":"9.4","Tissue RNA - tongue [nTPM]":"6.1","Tissue RNA - tonsil [nTPM]":"5.3","Tissue RNA - urinary bladder [nTPM]":"9.8","Tissue RNA - vagina [nTPM]":"15.2","Tissue RNA - white matter [nTPM]":"9.9","Cell RNA - A-431 [nTPM]":"7.3","Cell RNA - A549 [nTPM]":"5.8","Cell RNA - AF22 [nTPM]":"7.0","Cell RNA - AN3-CA [nTPM]":"9.3","Cell RNA - ASC diff [nTPM]":"5.0","Cell RNA - ASC TERT1 [nTPM]":"6.8","Cell RNA - BEWO [nTPM]":"15.7","Cell RNA - BJ [nTPM]":"4.9","Cell RNA - BJ hTERT+ [nTPM]":"4.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.1","Cell RNA - CACO-2 [nTPM]":"10.4","Cell RNA - CAPAN-2 [nTPM]":"5.2","Cell RNA - Daudi [nTPM]":"4.6","Cell RNA - EFO-21 [nTPM]":"3.2","Cell RNA - fHDF\/TERT166 [nTPM]":"3.5","Cell RNA - GAMG [nTPM]":"10.1","Cell RNA - HaCaT [nTPM]":"13.9","Cell RNA - HAP1 [nTPM]":"6.5","Cell RNA - HBEC3-KT [nTPM]":"5.4","Cell RNA - HBF TERT88 [nTPM]":"3.9","Cell RNA - HDLM-2 [nTPM]":"7.6","Cell RNA - HEK 293 [nTPM]":"10.8","Cell RNA - HEL [nTPM]":"2.4","Cell RNA - HeLa [nTPM]":"4.5","Cell RNA - Hep G2 [nTPM]":"5.2","Cell RNA - HHSteC [nTPM]":"3.7","Cell RNA - HL-60 [nTPM]":"2.6","Cell RNA - HMC-1 [nTPM]":"13.2","Cell RNA - HSkMC [nTPM]":"2.6","Cell RNA - hTCEpi [nTPM]":"6.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.2","Cell RNA - hTERT-HME1 [nTPM]":"6.6","Cell RNA - hTERT-RPE1 [nTPM]":"5.1","Cell RNA - HUVEC TERT2 [nTPM]":"4.2","Cell RNA - JURKAT [nTPM]":"5.3","Cell RNA - K-562 [nTPM]":"6.4","Cell RNA - Karpas-707 [nTPM]":"10.1","Cell RNA - LHCN-M2 [nTPM]":"2.4","Cell RNA - MCF7 [nTPM]":"6.0","Cell RNA - MOLT-4 [nTPM]":"6.9","Cell RNA - NB-4 [nTPM]":"13.6","Cell RNA - NTERA-2 [nTPM]":"6.8","Cell RNA - OE19 [nTPM]":"4.2","Cell RNA - PC-3 [nTPM]":"7.4","Cell RNA - REH [nTPM]":"6.4","Cell RNA - RH-30 [nTPM]":"7.1","Cell RNA - RPMI-8226 [nTPM]":"1.4","Cell RNA - RPTEC TERT1 [nTPM]":"3.8","Cell RNA - RT4 [nTPM]":"9.2","Cell RNA - SCLC-21H [nTPM]":"6.2","Cell RNA - SH-SY5Y [nTPM]":"4.4","Cell RNA - SiHa [nTPM]":"18.2","Cell RNA - SK-BR-3 [nTPM]":"6.8","Cell RNA - SK-MEL-30 [nTPM]":"10.7","Cell RNA - SuSa [nTPM]":"14.1","Cell RNA - T-47d [nTPM]":"8.5","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"3.0","Cell RNA - U-138 MG [nTPM]":"5.4","Cell RNA - U-2 OS [nTPM]":"5.2","Cell RNA - U-2197 [nTPM]":"5.2","Cell RNA - U-251 MG [nTPM]":"3.6","Cell RNA - U-266\/70 [nTPM]":"5.5","Cell RNA - U-266\/84 [nTPM]":"8.8","Cell RNA - U-698 [nTPM]":"5.6","Cell RNA - U-87 MG [nTPM]":"4.0","Cell RNA - U-937 [nTPM]":"3.3","Cell RNA - WM-115 [nTPM]":"3.3","Blood RNA - basophil [nTPM]":"7.3","Blood RNA - classical monocyte [nTPM]":"1.7","Blood RNA - eosinophil [nTPM]":"1.5","Blood RNA - gdT-cell [nTPM]":"1.9","Blood RNA - intermediate monocyte [nTPM]":"3.5","Blood RNA - MAIT T-cell [nTPM]":"2.1","Blood RNA - memory B-cell [nTPM]":"1.9","Blood RNA - memory CD4 T-cell [nTPM]":"2.5","Blood RNA - memory CD8 T-cell [nTPM]":"2.8","Blood RNA - myeloid DC [nTPM]":"3.1","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.5","Blood RNA - naive CD8 T-cell [nTPM]":"2.4","Blood RNA - neutrophil [nTPM]":"2.8","Blood RNA - NK-cell [nTPM]":"2.8","Blood RNA - non-classical monocyte [nTPM]":"3.0","Blood RNA - plasmacytoid DC [nTPM]":"1.7","Blood RNA - T-reg [nTPM]":"2.2","Blood RNA - total PBMC [nTPM]":"2.0","Brain RNA - amygdala [nTPM]":"6.7","Brain RNA - basal ganglia [nTPM]":"7.6","Brain RNA - cerebellum [nTPM]":"7.2","Brain RNA - cerebral cortex [nTPM]":"10.6","Brain RNA - hippocampal formation [nTPM]":"6.8","Brain RNA - hypothalamus [nTPM]":"6.9","Brain RNA - medulla oblongata [nTPM]":"7.3","Brain RNA - midbrain [nTPM]":"6.8","Brain RNA - pons [nTPM]":"7.3","Brain RNA - spinal cord [nTPM]":"7.1","Brain RNA - thalamus [nTPM]":"7.0","Brain RNA - white matter [nTPM]":"9.9","Single Cell Type RNA - Adipocytes [nTPM]":"23.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.6","Single Cell Type RNA - Astrocytes [nTPM]":"92.1","Single Cell Type RNA - B-cells [nTPM]":"26.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"26.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"38.1","Single Cell Type RNA - Bipolar cells [nTPM]":"7.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"10.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.5","Single Cell Type RNA - dendritic cells [nTPM]":"26.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"8.4","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"26.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"25.5","Single Cell Type RNA - Endothelial cells [nTPM]":"13.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"16.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"88.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.9","Single Cell Type RNA - Fibroblasts [nTPM]":"14.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"39.7","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"27.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"17.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.0","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"74.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"9.1","Single Cell Type RNA - Langerhans cells [nTPM]":"13.8","Single Cell Type RNA - Late spermatids [nTPM]":"2.0","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"19.9","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"116.2","Single Cell Type RNA - monocytes [nTPM]":"12.6","Single Cell Type RNA - Muller glia cells [nTPM]":"6.8","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"118.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"264.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.1","Single Cell Type RNA - Paneth cells [nTPM]":"17.4","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"31.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.0","Single Cell Type RNA - Spermatocytes [nTPM]":"14.1","Single Cell Type RNA - Spermatogonia [nTPM]":"12.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"29.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"26.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.9","Single Cell Type RNA - T-cells [nTPM]":"27.4","Single Cell Type RNA - Theca cells [nTPM]":"10.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.1","Single Cell Type RNA - Urothelial cells [nTPM]":"17.1"},{"Gene":"KDM6B","Gene synonym":["JMJD3","KIAA0346"],"Ensembl":"ENSG00000132510","Gene description":"Lysine demethylase 6B","Uniprot":["O15054"],"Chromosome":"17","Position":"7834217-7854796","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Inflammatory response"],"Molecular function":["Chromatin regulator","Dioxygenase","Oxidoreductase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"393.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"3.6","neutrophil":"8.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"granulocytes":"8.9"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037988"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 23: AN3-CA - Transcription regulation","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA037988":"AB_10672502"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.07e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.37e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Tissue RNA - adipose tissue [nTPM]":"33.6","Tissue RNA - adrenal gland [nTPM]":"13.3","Tissue RNA - amygdala [nTPM]":"3.1","Tissue RNA - appendix [nTPM]":"20.0","Tissue RNA - basal ganglia [nTPM]":"2.4","Tissue RNA - bone marrow [nTPM]":"35.5","Tissue RNA - breast [nTPM]":"12.6","Tissue RNA - cerebellum [nTPM]":"12.5","Tissue RNA - cerebral cortex [nTPM]":"22.9","Tissue RNA - cervix [nTPM]":"12.2","Tissue RNA - choroid plexus [nTPM]":"3.4","Tissue RNA - colon [nTPM]":"15.4","Tissue RNA - duodenum [nTPM]":"14.3","Tissue RNA - endometrium 1 [nTPM]":"14.0","Tissue RNA - epididymis [nTPM]":"3.4","Tissue RNA - esophagus [nTPM]":"13.6","Tissue RNA - fallopian tube [nTPM]":"17.1","Tissue RNA - gallbladder [nTPM]":"15.6","Tissue RNA - heart muscle [nTPM]":"17.7","Tissue RNA - hippocampal formation [nTPM]":"3.2","Tissue RNA - hypothalamus [nTPM]":"4.5","Tissue RNA - kidney [nTPM]":"14.6","Tissue RNA - liver [nTPM]":"15.2","Tissue RNA - lung [nTPM]":"27.4","Tissue RNA - lymph node [nTPM]":"8.0","Tissue RNA - medulla oblongata [nTPM]":"4.8","Tissue RNA - midbrain [nTPM]":"3.2","Tissue RNA - ovary [nTPM]":"29.7","Tissue RNA - pancreas [nTPM]":"17.1","Tissue RNA - parathyroid gland [nTPM]":"7.9","Tissue RNA - pituitary gland [nTPM]":"21.8","Tissue RNA - placenta [nTPM]":"6.8","Tissue RNA - pons [nTPM]":"3.3","Tissue RNA - prostate [nTPM]":"14.5","Tissue RNA - rectum [nTPM]":"4.1","Tissue RNA - retina [nTPM]":"6.2","Tissue RNA - salivary gland [nTPM]":"12.0","Tissue RNA - seminal vesicle [nTPM]":"6.2","Tissue RNA - skeletal muscle [nTPM]":"12.4","Tissue RNA - skin 1 [nTPM]":"16.4","Tissue RNA - small intestine [nTPM]":"17.5","Tissue RNA - smooth muscle [nTPM]":"5.5","Tissue RNA - spinal cord [nTPM]":"1.4","Tissue RNA - spleen [nTPM]":"20.7","Tissue RNA - stomach 1 [nTPM]":"17.7","Tissue RNA - testis [nTPM]":"16.1","Tissue RNA - thalamus [nTPM]":"5.0","Tissue RNA - thymus [nTPM]":"16.4","Tissue RNA - thyroid gland [nTPM]":"15.9","Tissue RNA - tongue [nTPM]":"8.2","Tissue RNA - tonsil [nTPM]":"4.6","Tissue RNA - urinary bladder [nTPM]":"19.8","Tissue RNA - vagina [nTPM]":"12.4","Tissue RNA - white matter [nTPM]":"6.2","Cell RNA - A-431 [nTPM]":"4.9","Cell RNA - A549 [nTPM]":"7.0","Cell RNA - AF22 [nTPM]":"12.5","Cell RNA - AN3-CA [nTPM]":"19.0","Cell RNA - ASC diff [nTPM]":"4.6","Cell RNA - ASC TERT1 [nTPM]":"3.4","Cell RNA - BEWO [nTPM]":"16.2","Cell RNA - BJ [nTPM]":"3.8","Cell RNA - BJ hTERT+ [nTPM]":"5.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.8","Cell RNA - CACO-2 [nTPM]":"9.3","Cell RNA - CAPAN-2 [nTPM]":"3.6","Cell RNA - Daudi [nTPM]":"11.4","Cell RNA - EFO-21 [nTPM]":"4.5","Cell RNA - fHDF\/TERT166 [nTPM]":"3.0","Cell RNA - GAMG [nTPM]":"3.9","Cell RNA - HaCaT [nTPM]":"12.2","Cell RNA - HAP1 [nTPM]":"5.8","Cell RNA - HBEC3-KT [nTPM]":"5.1","Cell RNA - HBF TERT88 [nTPM]":"1.6","Cell RNA - HDLM-2 [nTPM]":"4.7","Cell RNA - HEK 293 [nTPM]":"4.5","Cell RNA - HEL [nTPM]":"5.3","Cell RNA - HeLa [nTPM]":"6.7","Cell RNA - Hep G2 [nTPM]":"6.2","Cell RNA - HHSteC [nTPM]":"13.0","Cell RNA - HL-60 [nTPM]":"7.2","Cell RNA - HMC-1 [nTPM]":"15.6","Cell RNA - HSkMC [nTPM]":"5.3","Cell RNA - hTCEpi [nTPM]":"8.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.1","Cell RNA - hTERT-HME1 [nTPM]":"5.1","Cell RNA - hTERT-RPE1 [nTPM]":"7.2","Cell RNA - HUVEC TERT2 [nTPM]":"4.8","Cell RNA - JURKAT [nTPM]":"11.8","Cell RNA - K-562 [nTPM]":"8.8","Cell RNA - Karpas-707 [nTPM]":"4.8","Cell RNA - LHCN-M2 [nTPM]":"1.2","Cell RNA - MCF7 [nTPM]":"7.7","Cell RNA - MOLT-4 [nTPM]":"10.6","Cell RNA - NB-4 [nTPM]":"6.5","Cell RNA - NTERA-2 [nTPM]":"6.4","Cell RNA - OE19 [nTPM]":"4.9","Cell RNA - PC-3 [nTPM]":"3.9","Cell RNA - REH [nTPM]":"11.9","Cell RNA - RH-30 [nTPM]":"2.9","Cell RNA - RPMI-8226 [nTPM]":"3.2","Cell RNA - RPTEC TERT1 [nTPM]":"5.1","Cell RNA - RT4 [nTPM]":"7.7","Cell RNA - SCLC-21H [nTPM]":"6.6","Cell RNA - SH-SY5Y [nTPM]":"21.4","Cell RNA - SiHa [nTPM]":"4.8","Cell RNA - SK-BR-3 [nTPM]":"11.5","Cell RNA - SK-MEL-30 [nTPM]":"10.3","Cell RNA - SuSa [nTPM]":"7.3","Cell RNA - T-47d [nTPM]":"6.4","Cell RNA - THP-1 [nTPM]":"8.9","Cell RNA - TIME [nTPM]":"2.3","Cell RNA - U-138 MG [nTPM]":"4.0","Cell RNA - U-2 OS [nTPM]":"7.1","Cell RNA - U-2197 [nTPM]":"7.0","Cell RNA - U-251 MG [nTPM]":"5.5","Cell RNA - U-266\/70 [nTPM]":"5.6","Cell RNA - U-266\/84 [nTPM]":"1.2","Cell RNA - U-698 [nTPM]":"3.9","Cell RNA - U-87 MG [nTPM]":"5.3","Cell RNA - U-937 [nTPM]":"4.2","Cell RNA - WM-115 [nTPM]":"8.1","Blood RNA - basophil [nTPM]":"3.6","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"1.1","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"8.9","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"3.1","Brain RNA - basal ganglia [nTPM]":"2.4","Brain RNA - cerebellum [nTPM]":"12.5","Brain RNA - cerebral cortex [nTPM]":"22.9","Brain RNA - hippocampal formation [nTPM]":"3.2","Brain RNA - hypothalamus [nTPM]":"4.5","Brain RNA - medulla oblongata [nTPM]":"4.8","Brain RNA - midbrain [nTPM]":"3.2","Brain RNA - pons [nTPM]":"3.3","Brain RNA - spinal cord [nTPM]":"1.4","Brain RNA - thalamus [nTPM]":"5.0","Brain RNA - white matter [nTPM]":"6.2","Single Cell Type RNA - Adipocytes [nTPM]":"135.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"33.6","Single Cell Type RNA - Astrocytes [nTPM]":"6.2","Single Cell Type RNA - B-cells [nTPM]":"158.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"214.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"122.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"156.0","Single Cell Type RNA - Bipolar cells [nTPM]":"45.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"113.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"70.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"42.9","Single Cell Type RNA - Club cells [nTPM]":"32.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.1","Single Cell Type RNA - dendritic cells [nTPM]":"127.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"47.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"28.0","Single Cell Type RNA - Early spermatids [nTPM]":"29.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"88.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"67.1","Single Cell Type RNA - Endothelial cells [nTPM]":"80.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"79.9","Single Cell Type RNA - Erythroid cells [nTPM]":"8.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.9","Single Cell Type RNA - Fibroblasts [nTPM]":"85.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"73.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"181.6","Single Cell Type RNA - granulocytes [nTPM]":"178.6","Single Cell Type RNA - Granulosa cells [nTPM]":"44.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"34.2","Single Cell Type RNA - Hepatocytes [nTPM]":"22.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.4","Single Cell Type RNA - Horizontal cells [nTPM]":"38.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"62.5","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"50.4","Single Cell Type RNA - Langerhans cells [nTPM]":"393.1","Single Cell Type RNA - Late spermatids [nTPM]":"10.7","Single Cell Type RNA - Leydig cells [nTPM]":"16.4","Single Cell Type RNA - Macrophages [nTPM]":"219.2","Single Cell Type RNA - Melanocytes [nTPM]":"56.9","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"25.6","Single Cell Type RNA - Muller glia cells [nTPM]":"13.2","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"58.4","Single Cell Type RNA - Paneth cells [nTPM]":"49.1","Single Cell Type RNA - Peritubular cells [nTPM]":"13.9","Single Cell Type RNA - Plasma cells [nTPM]":"70.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"99.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"53.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.1","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"181.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"83.0","Single Cell Type RNA - Spermatocytes [nTPM]":"20.1","Single Cell Type RNA - Spermatogonia [nTPM]":"19.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"138.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"188.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"52.0","Single Cell Type RNA - T-cells [nTPM]":"104.1","Single Cell Type RNA - Theca cells [nTPM]":"22.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"46.2","Single Cell Type RNA - Urothelial cells [nTPM]":"86.6"},{"Gene":"KDSR","Gene synonym":["DHSR","FVT1","SDR35C1"],"Ensembl":"ENSG00000119537","Gene description":"3-ketodihydrosphingosine reductase","Uniprot":["Q06136"],"Chromosome":"18","Position":"63327726-63367228","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Cancer-related genes","Disease variant","Palmoplantar keratoderma","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-266\/70":"90.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003673","HPA044884"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB003673":"AB_425440","HPA044884":"AB_2679131"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.53e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-3"},"Tissue RNA - adipose tissue [nTPM]":"32.3","Tissue RNA - adrenal gland [nTPM]":"22.4","Tissue RNA - amygdala [nTPM]":"12.8","Tissue RNA - appendix [nTPM]":"8.1","Tissue RNA - basal ganglia [nTPM]":"19.9","Tissue RNA - bone marrow [nTPM]":"4.8","Tissue RNA - breast [nTPM]":"25.4","Tissue RNA - cerebellum [nTPM]":"19.5","Tissue RNA - cerebral cortex [nTPM]":"16.7","Tissue RNA - cervix [nTPM]":"26.9","Tissue RNA - choroid plexus [nTPM]":"12.3","Tissue RNA - colon [nTPM]":"24.6","Tissue RNA - duodenum [nTPM]":"7.0","Tissue RNA - endometrium 1 [nTPM]":"22.7","Tissue RNA - epididymis [nTPM]":"20.8","Tissue RNA - esophagus [nTPM]":"22.4","Tissue RNA - fallopian tube [nTPM]":"18.9","Tissue RNA - gallbladder [nTPM]":"12.6","Tissue RNA - heart muscle [nTPM]":"20.7","Tissue RNA - hippocampal formation [nTPM]":"12.7","Tissue RNA - hypothalamus [nTPM]":"16.4","Tissue RNA - kidney [nTPM]":"20.1","Tissue RNA - liver [nTPM]":"36.7","Tissue RNA - lung [nTPM]":"21.5","Tissue RNA - lymph node [nTPM]":"7.0","Tissue RNA - medulla oblongata [nTPM]":"20.6","Tissue RNA - midbrain [nTPM]":"17.7","Tissue RNA - ovary [nTPM]":"21.3","Tissue RNA - pancreas [nTPM]":"15.7","Tissue RNA - parathyroid gland [nTPM]":"13.1","Tissue RNA - pituitary gland [nTPM]":"12.1","Tissue RNA - placenta [nTPM]":"8.5","Tissue RNA - pons [nTPM]":"20.0","Tissue RNA - prostate [nTPM]":"16.3","Tissue RNA - rectum [nTPM]":"7.4","Tissue RNA - retina [nTPM]":"7.0","Tissue RNA - salivary gland [nTPM]":"22.8","Tissue RNA - seminal vesicle [nTPM]":"11.6","Tissue RNA - skeletal muscle [nTPM]":"16.7","Tissue RNA - skin 1 [nTPM]":"44.5","Tissue RNA - small intestine [nTPM]":"15.1","Tissue RNA - smooth muscle [nTPM]":"13.3","Tissue RNA - spinal cord [nTPM]":"17.6","Tissue RNA - spleen [nTPM]":"8.4","Tissue RNA - stomach 1 [nTPM]":"16.4","Tissue RNA - testis [nTPM]":"6.1","Tissue RNA - thalamus [nTPM]":"16.6","Tissue RNA - thymus [nTPM]":"7.1","Tissue RNA - thyroid gland [nTPM]":"17.2","Tissue RNA - tongue [nTPM]":"8.9","Tissue RNA - tonsil [nTPM]":"6.8","Tissue RNA - urinary bladder [nTPM]":"23.9","Tissue RNA - vagina [nTPM]":"23.4","Tissue RNA - white matter [nTPM]":"22.4","Cell RNA - A-431 [nTPM]":"14.9","Cell RNA - A549 [nTPM]":"6.5","Cell RNA - AF22 [nTPM]":"6.7","Cell RNA - AN3-CA [nTPM]":"7.5","Cell RNA - ASC diff [nTPM]":"52.6","Cell RNA - ASC TERT1 [nTPM]":"39.0","Cell RNA - BEWO [nTPM]":"13.0","Cell RNA - BJ [nTPM]":"48.8","Cell RNA - BJ hTERT+ [nTPM]":"29.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.9","Cell RNA - CACO-2 [nTPM]":"2.7","Cell RNA - CAPAN-2 [nTPM]":"10.0","Cell RNA - Daudi [nTPM]":"15.1","Cell RNA - EFO-21 [nTPM]":"20.3","Cell RNA - fHDF\/TERT166 [nTPM]":"19.1","Cell RNA - GAMG [nTPM]":"17.4","Cell RNA - HaCaT [nTPM]":"64.6","Cell RNA - HAP1 [nTPM]":"8.7","Cell RNA - HBEC3-KT [nTPM]":"27.3","Cell RNA - HBF TERT88 [nTPM]":"12.8","Cell RNA - HDLM-2 [nTPM]":"28.6","Cell RNA - HEK 293 [nTPM]":"14.5","Cell RNA - HEL [nTPM]":"11.6","Cell RNA - HeLa [nTPM]":"8.7","Cell RNA - Hep G2 [nTPM]":"3.4","Cell RNA - HHSteC [nTPM]":"40.1","Cell RNA - HL-60 [nTPM]":"22.0","Cell RNA - HMC-1 [nTPM]":"7.8","Cell RNA - HSkMC [nTPM]":"37.4","Cell RNA - hTCEpi [nTPM]":"50.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.8","Cell RNA - hTERT-HME1 [nTPM]":"47.9","Cell RNA - hTERT-RPE1 [nTPM]":"19.3","Cell RNA - HUVEC TERT2 [nTPM]":"10.5","Cell RNA - JURKAT [nTPM]":"9.9","Cell RNA - K-562 [nTPM]":"9.5","Cell RNA - Karpas-707 [nTPM]":"21.0","Cell RNA - LHCN-M2 [nTPM]":"28.1","Cell RNA - MCF7 [nTPM]":"6.2","Cell RNA - MOLT-4 [nTPM]":"23.6","Cell RNA - NB-4 [nTPM]":"9.7","Cell RNA - NTERA-2 [nTPM]":"8.0","Cell RNA - OE19 [nTPM]":"3.7","Cell RNA - PC-3 [nTPM]":"23.5","Cell RNA - REH [nTPM]":"15.5","Cell RNA - RH-30 [nTPM]":"19.7","Cell RNA - RPMI-8226 [nTPM]":"21.9","Cell RNA - RPTEC TERT1 [nTPM]":"29.0","Cell RNA - RT4 [nTPM]":"9.6","Cell RNA - SCLC-21H [nTPM]":"8.5","Cell RNA - SH-SY5Y [nTPM]":"16.4","Cell RNA - SiHa [nTPM]":"23.4","Cell RNA - SK-BR-3 [nTPM]":"11.3","Cell RNA - SK-MEL-30 [nTPM]":"21.9","Cell RNA - SuSa [nTPM]":"8.8","Cell RNA - T-47d [nTPM]":"6.1","Cell RNA - THP-1 [nTPM]":"12.1","Cell RNA - TIME [nTPM]":"24.9","Cell RNA - U-138 MG [nTPM]":"44.0","Cell RNA - U-2 OS [nTPM]":"10.6","Cell RNA - U-2197 [nTPM]":"14.8","Cell RNA - U-251 MG [nTPM]":"21.3","Cell RNA - U-266\/70 [nTPM]":"90.4","Cell RNA - U-266\/84 [nTPM]":"44.9","Cell RNA - U-698 [nTPM]":"8.7","Cell RNA - U-87 MG [nTPM]":"33.2","Cell RNA - U-937 [nTPM]":"13.0","Cell RNA - WM-115 [nTPM]":"13.4","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"5.2","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"6.5","Blood RNA - intermediate monocyte [nTPM]":"8.1","Blood RNA - MAIT T-cell [nTPM]":"26.6","Blood RNA - memory B-cell [nTPM]":"5.7","Blood RNA - memory CD4 T-cell [nTPM]":"13.6","Blood RNA - memory CD8 T-cell [nTPM]":"10.2","Blood RNA - myeloid DC [nTPM]":"8.0","Blood RNA - naive B-cell [nTPM]":"4.7","Blood RNA - naive CD4 T-cell [nTPM]":"9.3","Blood RNA - naive CD8 T-cell [nTPM]":"6.1","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"14.2","Blood RNA - non-classical monocyte [nTPM]":"3.9","Blood RNA - plasmacytoid DC [nTPM]":"3.8","Blood RNA - T-reg [nTPM]":"19.1","Blood RNA - total PBMC [nTPM]":"5.3","Brain RNA - amygdala [nTPM]":"12.8","Brain RNA - basal ganglia [nTPM]":"19.9","Brain RNA - cerebellum [nTPM]":"19.5","Brain RNA - cerebral cortex [nTPM]":"16.7","Brain RNA - hippocampal formation [nTPM]":"12.7","Brain RNA - hypothalamus [nTPM]":"16.4","Brain RNA - medulla oblongata [nTPM]":"20.6","Brain RNA - midbrain [nTPM]":"17.7","Brain RNA - pons [nTPM]":"20.0","Brain RNA - spinal cord [nTPM]":"17.6","Brain RNA - thalamus [nTPM]":"16.6","Brain RNA - white matter [nTPM]":"22.4","Single Cell Type RNA - Adipocytes [nTPM]":"53.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"49.1","Single Cell Type RNA - Astrocytes [nTPM]":"21.9","Single Cell Type RNA - B-cells [nTPM]":"30.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"158.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"131.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"47.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"122.3","Single Cell Type RNA - Bipolar cells [nTPM]":"37.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"63.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"63.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"27.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"62.9","Single Cell Type RNA - Club cells [nTPM]":"43.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"58.8","Single Cell Type RNA - dendritic cells [nTPM]":"15.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"34.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"50.7","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"43.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"53.0","Single Cell Type RNA - Endothelial cells [nTPM]":"48.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.4","Single Cell Type RNA - Erythroid cells [nTPM]":"17.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"36.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"70.4","Single Cell Type RNA - Fibroblasts [nTPM]":"82.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"26.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"64.9","Single Cell Type RNA - granulocytes [nTPM]":"26.0","Single Cell Type RNA - Granulosa cells [nTPM]":"52.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"51.8","Single Cell Type RNA - Hepatocytes [nTPM]":"88.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"36.4","Single Cell Type RNA - Horizontal cells [nTPM]":"40.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.8","Single Cell Type RNA - Ionocytes [nTPM]":"42.7","Single Cell Type RNA - Kupffer cells [nTPM]":"32.2","Single Cell Type RNA - Langerhans cells [nTPM]":"47.7","Single Cell Type RNA - Late spermatids [nTPM]":"6.5","Single Cell Type RNA - Leydig cells [nTPM]":"71.1","Single Cell Type RNA - Macrophages [nTPM]":"39.9","Single Cell Type RNA - Melanocytes [nTPM]":"56.9","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"31.5","Single Cell Type RNA - Muller glia cells [nTPM]":"56.5","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"57.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"47.4","Single Cell Type RNA - Paneth cells [nTPM]":"44.6","Single Cell Type RNA - Peritubular cells [nTPM]":"70.7","Single Cell Type RNA - Plasma cells [nTPM]":"24.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"104.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"43.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"39.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"41.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"41.1","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"73.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"48.4","Single Cell Type RNA - Spermatocytes [nTPM]":"1.3","Single Cell Type RNA - Spermatogonia [nTPM]":"5.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"89.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"143.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"91.4","Single Cell Type RNA - T-cells [nTPM]":"37.7","Single Cell Type RNA - Theca cells [nTPM]":"51.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"40.3","Single Cell Type RNA - Urothelial cells [nTPM]":"94.7"},{"Gene":"KHK","Gene synonym":[],"Ensembl":"ENSG00000138030","Gene description":"Ketohexokinase","Uniprot":["P50053"],"Chromosome":"2","Position":"27086747-27100762","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"intestine":"121.2","kidney":"104.4","liver":"180.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"428.5","Proximal enterocytes":"1858.7","Proximal tubular cells":"1019.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"liver cancer":"62.2","renal cancer":"32.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"32.8","Hep G2":"48.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007040"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"620000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA007040":"AB_1079185"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.62e-8"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.2","Tissue RNA - adrenal gland [nTPM]":"4.6","Tissue RNA - amygdala [nTPM]":"4.2","Tissue RNA - appendix [nTPM]":"3.0","Tissue RNA - basal ganglia [nTPM]":"4.3","Tissue RNA - bone marrow [nTPM]":"1.7","Tissue RNA - breast [nTPM]":"2.0","Tissue RNA - cerebellum [nTPM]":"7.1","Tissue RNA - cerebral cortex [nTPM]":"5.9","Tissue RNA - cervix [nTPM]":"2.6","Tissue RNA - choroid plexus [nTPM]":"1.2","Tissue RNA - colon [nTPM]":"4.2","Tissue RNA - duodenum [nTPM]":"112.4","Tissue RNA - endometrium 1 [nTPM]":"3.8","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"2.4","Tissue RNA - fallopian tube [nTPM]":"4.3","Tissue RNA - gallbladder [nTPM]":"1.3","Tissue RNA - heart muscle [nTPM]":"1.4","Tissue RNA - hippocampal formation [nTPM]":"4.8","Tissue RNA - hypothalamus [nTPM]":"3.9","Tissue RNA - kidney [nTPM]":"104.4","Tissue RNA - liver [nTPM]":"180.5","Tissue RNA - lung [nTPM]":"1.6","Tissue RNA - lymph node [nTPM]":"1.9","Tissue RNA - medulla oblongata [nTPM]":"5.4","Tissue RNA - midbrain [nTPM]":"4.0","Tissue RNA - ovary [nTPM]":"3.6","Tissue RNA - pancreas [nTPM]":"9.4","Tissue RNA - parathyroid gland [nTPM]":"2.6","Tissue RNA - pituitary gland [nTPM]":"1.4","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"5.5","Tissue RNA - prostate [nTPM]":"1.6","Tissue RNA - rectum [nTPM]":"1.2","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"4.4","Tissue RNA - seminal vesicle [nTPM]":"1.4","Tissue RNA - skeletal muscle [nTPM]":"3.8","Tissue RNA - skin 1 [nTPM]":"2.4","Tissue RNA - small intestine [nTPM]":"121.2","Tissue RNA - smooth muscle [nTPM]":"1.9","Tissue RNA - spinal cord [nTPM]":"3.6","Tissue RNA - spleen [nTPM]":"2.0","Tissue RNA - stomach 1 [nTPM]":"2.9","Tissue RNA - testis [nTPM]":"3.2","Tissue RNA - thalamus [nTPM]":"3.8","Tissue RNA - thymus [nTPM]":"0.7","Tissue RNA - thyroid gland [nTPM]":"1.1","Tissue RNA - tongue [nTPM]":"2.0","Tissue RNA - tonsil [nTPM]":"1.2","Tissue RNA - urinary bladder [nTPM]":"1.8","Tissue RNA - vagina [nTPM]":"2.3","Tissue RNA - white matter [nTPM]":"4.7","Cell RNA - A-431 [nTPM]":"25.0","Cell RNA - A549 [nTPM]":"18.5","Cell RNA - AF22 [nTPM]":"2.8","Cell RNA - AN3-CA [nTPM]":"11.0","Cell RNA - ASC diff [nTPM]":"2.0","Cell RNA - ASC TERT1 [nTPM]":"0.5","Cell RNA - BEWO [nTPM]":"2.5","Cell RNA - BJ [nTPM]":"1.7","Cell RNA - BJ hTERT+ [nTPM]":"1.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.4","Cell RNA - CACO-2 [nTPM]":"9.0","Cell RNA - CAPAN-2 [nTPM]":"5.3","Cell RNA - Daudi [nTPM]":"3.7","Cell RNA - EFO-21 [nTPM]":"5.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"2.6","Cell RNA - HaCaT [nTPM]":"10.7","Cell RNA - HAP1 [nTPM]":"9.4","Cell RNA - HBEC3-KT [nTPM]":"3.1","Cell RNA - HBF TERT88 [nTPM]":"0.8","Cell RNA - HDLM-2 [nTPM]":"8.8","Cell RNA - HEK 293 [nTPM]":"17.2","Cell RNA - HEL [nTPM]":"32.8","Cell RNA - HeLa [nTPM]":"5.2","Cell RNA - Hep G2 [nTPM]":"48.0","Cell RNA - HHSteC [nTPM]":"1.1","Cell RNA - HL-60 [nTPM]":"4.6","Cell RNA - HMC-1 [nTPM]":"3.7","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"1.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.7","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"1.2","Cell RNA - HUVEC TERT2 [nTPM]":"2.1","Cell RNA - JURKAT [nTPM]":"5.1","Cell RNA - K-562 [nTPM]":"5.9","Cell RNA - Karpas-707 [nTPM]":"6.1","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"16.0","Cell RNA - MOLT-4 [nTPM]":"5.4","Cell RNA - NB-4 [nTPM]":"3.6","Cell RNA - NTERA-2 [nTPM]":"4.0","Cell RNA - OE19 [nTPM]":"22.3","Cell RNA - PC-3 [nTPM]":"7.2","Cell RNA - REH [nTPM]":"18.9","Cell RNA - RH-30 [nTPM]":"1.4","Cell RNA - RPMI-8226 [nTPM]":"20.9","Cell RNA - RPTEC TERT1 [nTPM]":"2.7","Cell RNA - RT4 [nTPM]":"3.0","Cell RNA - SCLC-21H [nTPM]":"10.2","Cell RNA - SH-SY5Y [nTPM]":"15.8","Cell RNA - SiHa [nTPM]":"3.6","Cell RNA - SK-BR-3 [nTPM]":"6.2","Cell RNA - SK-MEL-30 [nTPM]":"6.9","Cell RNA - SuSa [nTPM]":"1.0","Cell RNA - T-47d [nTPM]":"2.7","Cell RNA - THP-1 [nTPM]":"2.0","Cell RNA - TIME [nTPM]":"1.9","Cell RNA - U-138 MG [nTPM]":"0.7","Cell RNA - U-2 OS [nTPM]":"3.6","Cell RNA - U-2197 [nTPM]":"1.6","Cell RNA - U-251 MG [nTPM]":"6.5","Cell RNA - U-266\/70 [nTPM]":"7.5","Cell RNA - U-266\/84 [nTPM]":"14.4","Cell RNA - U-698 [nTPM]":"6.3","Cell RNA - U-87 MG [nTPM]":"3.0","Cell RNA - U-937 [nTPM]":"10.7","Cell RNA - WM-115 [nTPM]":"1.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"5.4","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"4.1","Blood RNA - intermediate monocyte [nTPM]":"3.1","Blood RNA - MAIT T-cell [nTPM]":"5.5","Blood RNA - memory B-cell [nTPM]":"3.8","Blood RNA - memory CD4 T-cell [nTPM]":"6.6","Blood RNA - memory CD8 T-cell [nTPM]":"6.0","Blood RNA - myeloid DC [nTPM]":"4.9","Blood RNA - naive B-cell [nTPM]":"3.6","Blood RNA - naive CD4 T-cell [nTPM]":"4.7","Blood RNA - naive CD8 T-cell [nTPM]":"5.8","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"4.9","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"6.1","Blood RNA - T-reg [nTPM]":"4.7","Blood RNA - total PBMC [nTPM]":"4.9","Brain RNA - amygdala [nTPM]":"4.2","Brain RNA - basal ganglia [nTPM]":"4.3","Brain RNA - cerebellum [nTPM]":"7.1","Brain RNA - cerebral cortex [nTPM]":"5.9","Brain RNA - hippocampal formation [nTPM]":"4.8","Brain RNA - hypothalamus [nTPM]":"3.9","Brain RNA - medulla oblongata [nTPM]":"5.4","Brain RNA - midbrain [nTPM]":"4.0","Brain RNA - pons [nTPM]":"5.5","Brain RNA - spinal cord [nTPM]":"3.6","Brain RNA - thalamus [nTPM]":"3.8","Brain RNA - white matter [nTPM]":"4.7","Single Cell Type RNA - Adipocytes [nTPM]":"6.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.7","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"6.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"3.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"1.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.1","Single Cell Type RNA - dendritic cells [nTPM]":"1.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"129.1","Single Cell Type RNA - Ductal cells [nTPM]":"3.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.6","Single Cell Type RNA - Endothelial cells [nTPM]":"5.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"15.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.6","Single Cell Type RNA - Fibroblasts [nTPM]":"2.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"2.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.7","Single Cell Type RNA - Hepatocytes [nTPM]":"428.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.3","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"89.6","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"11.9","Single Cell Type RNA - Langerhans cells [nTPM]":"2.0","Single Cell Type RNA - Late spermatids [nTPM]":"6.2","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"10.8","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.9","Single Cell Type RNA - Muller glia cells [nTPM]":"9.8","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.1","Single Cell Type RNA - Paneth cells [nTPM]":"95.7","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"8.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1858.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1019.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.0","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"5.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.4","Single Cell Type RNA - T-cells [nTPM]":"6.8","Single Cell Type RNA - Theca cells [nTPM]":"0.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"82.6","Single Cell Type RNA - Urothelial cells [nTPM]":"2.2"},{"Gene":"KIDINS220","Gene synonym":["ARMS"],"Ensembl":"ENSG00000134313","Gene description":"Kinase D interacting substrate 220","Uniprot":["Q9ULH0"],"Chromosome":"2","Position":"8721081-8837630","Protein class":["Disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Neurogenesis"],"Molecular function":null,"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Mental retardation","Neurodegeneration","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"322.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014790"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA014790":"AB_1852460"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.64e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.29e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Tissue RNA - adipose tissue [nTPM]":"21.2","Tissue RNA - adrenal gland [nTPM]":"21.6","Tissue RNA - amygdala [nTPM]":"20.9","Tissue RNA - appendix [nTPM]":"14.5","Tissue RNA - basal ganglia [nTPM]":"40.6","Tissue RNA - bone marrow [nTPM]":"24.4","Tissue RNA - breast [nTPM]":"19.6","Tissue RNA - cerebellum [nTPM]":"34.9","Tissue RNA - cerebral cortex [nTPM]":"27.5","Tissue RNA - cervix [nTPM]":"22.3","Tissue RNA - choroid plexus [nTPM]":"21.6","Tissue RNA - colon [nTPM]":"19.6","Tissue RNA - duodenum [nTPM]":"11.4","Tissue RNA - endometrium 1 [nTPM]":"29.3","Tissue RNA - epididymis [nTPM]":"15.3","Tissue RNA - esophagus [nTPM]":"15.1","Tissue RNA - fallopian tube [nTPM]":"16.6","Tissue RNA - gallbladder [nTPM]":"17.7","Tissue RNA - heart muscle [nTPM]":"21.9","Tissue RNA - hippocampal formation [nTPM]":"22.1","Tissue RNA - hypothalamus [nTPM]":"28.9","Tissue RNA - kidney [nTPM]":"22.1","Tissue RNA - liver [nTPM]":"15.7","Tissue RNA - lung [nTPM]":"23.6","Tissue RNA - lymph node [nTPM]":"13.1","Tissue RNA - medulla oblongata [nTPM]":"43.9","Tissue RNA - midbrain [nTPM]":"31.5","Tissue RNA - ovary [nTPM]":"37.7","Tissue RNA - pancreas [nTPM]":"18.8","Tissue RNA - parathyroid gland [nTPM]":"42.8","Tissue RNA - pituitary gland [nTPM]":"16.9","Tissue RNA - placenta [nTPM]":"21.4","Tissue RNA - pons [nTPM]":"43.4","Tissue RNA - prostate [nTPM]":"20.0","Tissue RNA - rectum [nTPM]":"16.5","Tissue RNA - retina [nTPM]":"38.0","Tissue RNA - salivary gland [nTPM]":"14.5","Tissue RNA - seminal vesicle [nTPM]":"18.0","Tissue RNA - skeletal muscle [nTPM]":"14.5","Tissue RNA - skin 1 [nTPM]":"16.7","Tissue RNA - small intestine [nTPM]":"13.8","Tissue RNA - smooth muscle [nTPM]":"23.6","Tissue RNA - spinal cord [nTPM]":"35.7","Tissue RNA - spleen [nTPM]":"17.1","Tissue RNA - stomach 1 [nTPM]":"16.5","Tissue RNA - testis [nTPM]":"10.6","Tissue RNA - thalamus [nTPM]":"32.0","Tissue RNA - thymus [nTPM]":"21.6","Tissue RNA - thyroid gland [nTPM]":"20.0","Tissue RNA - tongue [nTPM]":"16.7","Tissue RNA - tonsil [nTPM]":"12.3","Tissue RNA - urinary bladder [nTPM]":"16.7","Tissue RNA - vagina [nTPM]":"17.9","Tissue RNA - white matter [nTPM]":"73.9","Cell RNA - A-431 [nTPM]":"13.5","Cell RNA - A549 [nTPM]":"21.3","Cell RNA - AF22 [nTPM]":"41.8","Cell RNA - AN3-CA [nTPM]":"26.8","Cell RNA - ASC diff [nTPM]":"51.4","Cell RNA - ASC TERT1 [nTPM]":"33.9","Cell RNA - BEWO [nTPM]":"21.9","Cell RNA - BJ [nTPM]":"26.2","Cell RNA - BJ hTERT+ [nTPM]":"21.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.0","Cell RNA - CACO-2 [nTPM]":"21.5","Cell RNA - CAPAN-2 [nTPM]":"13.5","Cell RNA - Daudi [nTPM]":"25.2","Cell RNA - EFO-21 [nTPM]":"26.1","Cell RNA - fHDF\/TERT166 [nTPM]":"39.4","Cell RNA - GAMG [nTPM]":"31.5","Cell RNA - HaCaT [nTPM]":"22.5","Cell RNA - HAP1 [nTPM]":"37.9","Cell RNA - HBEC3-KT [nTPM]":"16.1","Cell RNA - HBF TERT88 [nTPM]":"24.0","Cell RNA - HDLM-2 [nTPM]":"36.4","Cell RNA - HEK 293 [nTPM]":"25.7","Cell RNA - HEL [nTPM]":"22.7","Cell RNA - HeLa [nTPM]":"15.9","Cell RNA - Hep G2 [nTPM]":"22.6","Cell RNA - HHSteC [nTPM]":"36.3","Cell RNA - HL-60 [nTPM]":"23.6","Cell RNA - HMC-1 [nTPM]":"29.9","Cell RNA - HSkMC [nTPM]":"35.3","Cell RNA - hTCEpi [nTPM]":"24.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.1","Cell RNA - hTERT-HME1 [nTPM]":"33.7","Cell RNA - hTERT-RPE1 [nTPM]":"25.1","Cell RNA - HUVEC TERT2 [nTPM]":"25.9","Cell RNA - JURKAT [nTPM]":"21.6","Cell RNA - K-562 [nTPM]":"44.7","Cell RNA - Karpas-707 [nTPM]":"30.8","Cell RNA - LHCN-M2 [nTPM]":"29.2","Cell RNA - MCF7 [nTPM]":"14.8","Cell RNA - MOLT-4 [nTPM]":"24.2","Cell RNA - NB-4 [nTPM]":"12.7","Cell RNA - NTERA-2 [nTPM]":"22.7","Cell RNA - OE19 [nTPM]":"22.3","Cell RNA - PC-3 [nTPM]":"18.8","Cell RNA - REH [nTPM]":"22.7","Cell RNA - RH-30 [nTPM]":"30.7","Cell RNA - RPMI-8226 [nTPM]":"12.7","Cell RNA - RPTEC TERT1 [nTPM]":"21.7","Cell RNA - RT4 [nTPM]":"25.4","Cell RNA - SCLC-21H [nTPM]":"35.4","Cell RNA - SH-SY5Y [nTPM]":"59.3","Cell RNA - SiHa [nTPM]":"20.8","Cell RNA - SK-BR-3 [nTPM]":"20.7","Cell RNA - SK-MEL-30 [nTPM]":"23.6","Cell RNA - SuSa [nTPM]":"21.7","Cell RNA - T-47d [nTPM]":"13.3","Cell RNA - THP-1 [nTPM]":"26.6","Cell RNA - TIME [nTPM]":"34.4","Cell RNA - U-138 MG [nTPM]":"36.1","Cell RNA - U-2 OS [nTPM]":"19.0","Cell RNA - U-2197 [nTPM]":"36.6","Cell RNA - U-251 MG [nTPM]":"28.5","Cell RNA - U-266\/70 [nTPM]":"22.4","Cell RNA - U-266\/84 [nTPM]":"21.1","Cell RNA - U-698 [nTPM]":"33.5","Cell RNA - U-87 MG [nTPM]":"21.1","Cell RNA - U-937 [nTPM]":"31.2","Cell RNA - WM-115 [nTPM]":"28.1","Blood RNA - basophil [nTPM]":"4.1","Blood RNA - classical monocyte [nTPM]":"3.4","Blood RNA - eosinophil [nTPM]":"4.2","Blood RNA - gdT-cell [nTPM]":"3.6","Blood RNA - intermediate monocyte [nTPM]":"3.9","Blood RNA - MAIT T-cell [nTPM]":"2.6","Blood RNA - memory B-cell [nTPM]":"1.9","Blood RNA - memory CD4 T-cell [nTPM]":"2.6","Blood RNA - memory CD8 T-cell [nTPM]":"3.0","Blood RNA - myeloid DC [nTPM]":"2.7","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"2.7","Blood RNA - naive CD8 T-cell [nTPM]":"3.1","Blood RNA - neutrophil [nTPM]":"5.3","Blood RNA - NK-cell [nTPM]":"3.2","Blood RNA - non-classical monocyte [nTPM]":"4.6","Blood RNA - plasmacytoid DC [nTPM]":"1.8","Blood RNA - T-reg [nTPM]":"2.4","Blood RNA - total PBMC [nTPM]":"2.2","Brain RNA - amygdala [nTPM]":"20.9","Brain RNA - basal ganglia [nTPM]":"40.6","Brain RNA - cerebellum [nTPM]":"34.9","Brain RNA - cerebral cortex [nTPM]":"27.5","Brain RNA - hippocampal formation [nTPM]":"22.1","Brain RNA - hypothalamus [nTPM]":"28.9","Brain RNA - medulla oblongata [nTPM]":"43.9","Brain RNA - midbrain [nTPM]":"31.5","Brain RNA - pons [nTPM]":"43.4","Brain RNA - spinal cord [nTPM]":"35.7","Brain RNA - thalamus [nTPM]":"32.0","Brain RNA - white matter [nTPM]":"73.9","Single Cell Type RNA - Adipocytes [nTPM]":"57.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"99.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"115.7","Single Cell Type RNA - Astrocytes [nTPM]":"129.6","Single Cell Type RNA - B-cells [nTPM]":"25.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"32.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"25.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.9","Single Cell Type RNA - Bipolar cells [nTPM]":"86.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"31.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"25.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"40.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"48.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"139.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"21.5","Single Cell Type RNA - dendritic cells [nTPM]":"35.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"33.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"33.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"32.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"77.8","Single Cell Type RNA - Endothelial cells [nTPM]":"51.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"43.3","Single Cell Type RNA - Erythroid cells [nTPM]":"36.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"108.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.0","Single Cell Type RNA - Fibroblasts [nTPM]":"55.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"39.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"53.1","Single Cell Type RNA - granulocytes [nTPM]":"35.4","Single Cell Type RNA - Granulosa cells [nTPM]":"144.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"47.8","Single Cell Type RNA - Hepatocytes [nTPM]":"30.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.8","Single Cell Type RNA - Horizontal cells [nTPM]":"154.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"149.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.4","Single Cell Type RNA - Ionocytes [nTPM]":"44.7","Single Cell Type RNA - Kupffer cells [nTPM]":"52.7","Single Cell Type RNA - Langerhans cells [nTPM]":"46.0","Single Cell Type RNA - Late spermatids [nTPM]":"5.9","Single Cell Type RNA - Leydig cells [nTPM]":"69.6","Single Cell Type RNA - Macrophages [nTPM]":"45.9","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"60.9","Single Cell Type RNA - monocytes [nTPM]":"44.2","Single Cell Type RNA - Muller glia cells [nTPM]":"60.5","Single Cell Type RNA - NK-cells [nTPM]":"34.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"162.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"322.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.0","Single Cell Type RNA - Paneth cells [nTPM]":"29.8","Single Cell Type RNA - Peritubular cells [nTPM]":"65.5","Single Cell Type RNA - Plasma cells [nTPM]":"27.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"25.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"34.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"58.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"65.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"54.2","Single Cell Type RNA - Spermatocytes [nTPM]":"28.1","Single Cell Type RNA - Spermatogonia [nTPM]":"23.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"29.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.9","Single Cell Type RNA - T-cells [nTPM]":"40.2","Single Cell Type RNA - Theca cells [nTPM]":"52.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.9","Single Cell Type RNA - Urothelial cells [nTPM]":"36.0"},{"Gene":"KISS1R","Gene synonym":["AXOR12","GPR54","HOT7T175"],"Ensembl":"ENSG00000116014","Gene description":"KISS1 receptor","Uniprot":["Q969F8"],"Chromosome":"19","Position":"917287-921005","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","Hypogonadotropic hypogonadism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"8.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Extravillous trophoblasts":"41.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"3.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"K-562":"15.7","RPMI-8226":"37.4","SCLC-21H":"7.4","SH-SY5Y":"20.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007156","HPA071913"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA007156":null,"HPA071913":"AB_2686471"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.33e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"2.9","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"1.8","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.9","Tissue RNA - cerebral cortex [nTPM]":"3.4","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"1.3","Tissue RNA - hypothalamus [nTPM]":"3.8","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"4.0","Tissue RNA - midbrain [nTPM]":"2.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"1.3","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"1.1","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"3.9","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"8.5","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.7","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"2.4","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"1.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"4.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"4.8","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"15.7","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"1.2","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"1.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"37.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"7.4","Cell RNA - SH-SY5Y [nTPM]":"20.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.4","Cell RNA - THP-1 [nTPM]":"0.9","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.9","Brain RNA - basal ganglia [nTPM]":"1.8","Brain RNA - cerebellum [nTPM]":"0.9","Brain RNA - cerebral cortex [nTPM]":"3.4","Brain RNA - hippocampal formation [nTPM]":"1.3","Brain RNA - hypothalamus [nTPM]":"3.8","Brain RNA - medulla oblongata [nTPM]":"4.0","Brain RNA - midbrain [nTPM]":"2.2","Brain RNA - pons [nTPM]":"3.9","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"8.5","Brain RNA - white matter [nTPM]":"0.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"41.9","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"4.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.6","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"KL","Gene synonym":[],"Ensembl":"ENSG00000133116","Gene description":"Klotho","Uniprot":["Q9UEF7"],"Chromosome":"13","Position":"33016423-33066143","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":null,"Molecular function":["Glycosidase","Hormone","Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"47.1","kidney":"128.7","parathyroid gland":"135.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Proximal tubular cells":"123.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"prostate cancer":"5.9","renal cancer":"17.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"HMC-1":"2.4","SK-BR-3":"4.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"basal ganglia":"13.3","cerebral cortex":"6.7","hippocampal formation":"7.4","medulla oblongata":"4.2"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":510000,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.44e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.29e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.3","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"0.9","Tissue RNA - appendix [nTPM]":"0.8","Tissue RNA - basal ganglia [nTPM]":"3.1","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"2.5","Tissue RNA - cerebellum [nTPM]":"0.8","Tissue RNA - cerebral cortex [nTPM]":"1.5","Tissue RNA - cervix [nTPM]":"1.8","Tissue RNA - choroid plexus [nTPM]":"47.1","Tissue RNA - colon [nTPM]":"2.1","Tissue RNA - duodenum [nTPM]":"2.7","Tissue RNA - endometrium 1 [nTPM]":"1.2","Tissue RNA - epididymis [nTPM]":"8.8","Tissue RNA - esophagus [nTPM]":"1.1","Tissue RNA - fallopian tube [nTPM]":"0.8","Tissue RNA - gallbladder [nTPM]":"1.3","Tissue RNA - heart muscle [nTPM]":"1.1","Tissue RNA - hippocampal formation [nTPM]":"4.2","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"128.7","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"3.5","Tissue RNA - lymph node [nTPM]":"1.0","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.5","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"1.2","Tissue RNA - parathyroid gland [nTPM]":"135.2","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"30.4","Tissue RNA - pons [nTPM]":"0.5","Tissue RNA - prostate [nTPM]":"8.0","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.8","Tissue RNA - seminal vesicle [nTPM]":"2.5","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"2.6","Tissue RNA - smooth muscle [nTPM]":"1.2","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"2.4","Tissue RNA - stomach 1 [nTPM]":"2.0","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"0.8","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"1.3","Tissue RNA - tongue [nTPM]":"1.5","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"1.6","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.7","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"2.4","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"4.5","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.9","Brain RNA - basal ganglia [nTPM]":"3.1","Brain RNA - cerebellum [nTPM]":"0.8","Brain RNA - cerebral cortex [nTPM]":"1.5","Brain RNA - hippocampal formation [nTPM]":"4.2","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.5","Brain RNA - pons [nTPM]":"0.5","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"0.8","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"15.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.5","Single Cell Type RNA - Endothelial cells [nTPM]":"10.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.3","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.9","Single Cell Type RNA - Langerhans cells [nTPM]":"1.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"1.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"0.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"123.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.9","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"KLK4","Gene synonym":["EMSP","EMSP1","KLK-L1","PRSS17","PSTS"],"Ensembl":"ENSG00000167749","Gene description":"Kallikrein related peptidase 4","Uniprot":["Q9Y5K2"],"Chromosome":"19","Position":"50906352-50910738","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Biomineralization"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Amelogenesis imperfecta","Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"32","RNA tissue specific nTPM":{"prostate":"286.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"Prostatic glandular cells":"106.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"55","RNA cancer specific FPKM":{"prostate cancer":"463.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"6.4","HaCaT":"7.9","OE19":"7.3","SK-BR-3":"5.1"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"4.5"},"Antibody":["HPA051839"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in male reproductive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 51: Non-specific - Unknown function","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 35: Glandular cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051839":"AB_2681632"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.23e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"2.9","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"1.5","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"1.1","Tissue RNA - breast [nTPM]":"1.7","Tissue RNA - cerebellum [nTPM]":"1.7","Tissue RNA - cerebral cortex [nTPM]":"1.2","Tissue RNA - cervix [nTPM]":"6.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"3.0","Tissue RNA - duodenum [nTPM]":"7.3","Tissue RNA - endometrium 1 [nTPM]":"4.4","Tissue RNA - epididymis [nTPM]":"1.1","Tissue RNA - esophagus [nTPM]":"2.1","Tissue RNA - fallopian tube [nTPM]":"0.6","Tissue RNA - gallbladder [nTPM]":"1.0","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.8","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.8","Tissue RNA - medulla oblongata [nTPM]":"1.6","Tissue RNA - midbrain [nTPM]":"0.8","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.9","Tissue RNA - parathyroid gland [nTPM]":"1.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"1.6","Tissue RNA - prostate [nTPM]":"286.4","Tissue RNA - rectum [nTPM]":"3.6","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"4.8","Tissue RNA - seminal vesicle [nTPM]":"2.7","Tissue RNA - skeletal muscle [nTPM]":"3.5","Tissue RNA - skin 1 [nTPM]":"8.9","Tissue RNA - small intestine [nTPM]":"5.1","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"1.9","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"3.8","Tissue RNA - tongue [nTPM]":"1.3","Tissue RNA - tonsil [nTPM]":"0.8","Tissue RNA - urinary bladder [nTPM]":"1.2","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"4.1","Cell RNA - A549 [nTPM]":"1.6","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"3.5","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"3.5","Cell RNA - CAPAN-2 [nTPM]":"6.4","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"7.9","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"4.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"1.1","Cell RNA - HEK 293 [nTPM]":"1.1","Cell RNA - HEL [nTPM]":"1.3","Cell RNA - HeLa [nTPM]":"3.8","Cell RNA - Hep G2 [nTPM]":"1.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"1.4","Cell RNA - HMC-1 [nTPM]":"1.7","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"1.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"3.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"2.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"7.3","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.9","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"2.6","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.4","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"5.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"4.0","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.9","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"1.0","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"2.0","Cell RNA - U-266\/84 [nTPM]":"0.9","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"1.7","Brain RNA - cerebral cortex [nTPM]":"1.2","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.8","Brain RNA - medulla oblongata [nTPM]":"1.6","Brain RNA - midbrain [nTPM]":"0.8","Brain RNA - pons [nTPM]":"1.6","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"5.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"106.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"3.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.0","Single Cell Type RNA - Urothelial cells [nTPM]":"2.6"},{"Gene":"KMT2A","Gene synonym":["ALL-1","CXXC7","HRX","HTRX1","MLL","MLL1A","TRX1"],"Ensembl":"ENSG00000118058","Gene description":"Lysine methyltransferase 2A","Uniprot":["Q03164"],"Chromosome":"11","Position":"118436490-118526832","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transcription factors"],"Biological process":["Apoptosis","Biological rhythms","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Methyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017794","CAB024270","HPA044910"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB017794":null,"CAB024270":null,"HPA044910":"AB_2679141"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.9","Tissue RNA - adrenal gland [nTPM]":"6.7","Tissue RNA - amygdala [nTPM]":"8.0","Tissue RNA - appendix [nTPM]":"8.5","Tissue RNA - basal ganglia [nTPM]":"8.6","Tissue RNA - bone marrow [nTPM]":"19.5","Tissue RNA - breast [nTPM]":"9.9","Tissue RNA - cerebellum [nTPM]":"21.2","Tissue RNA - cerebral cortex [nTPM]":"9.3","Tissue RNA - cervix [nTPM]":"10.3","Tissue RNA - choroid plexus [nTPM]":"1.6","Tissue RNA - colon [nTPM]":"10.8","Tissue RNA - duodenum [nTPM]":"5.4","Tissue RNA - endometrium 1 [nTPM]":"10.7","Tissue RNA - epididymis [nTPM]":"8.2","Tissue RNA - esophagus [nTPM]":"6.8","Tissue RNA - fallopian tube [nTPM]":"10.3","Tissue RNA - gallbladder [nTPM]":"6.4","Tissue RNA - heart muscle [nTPM]":"6.5","Tissue RNA - hippocampal formation [nTPM]":"7.4","Tissue RNA - hypothalamus [nTPM]":"9.6","Tissue RNA - kidney [nTPM]":"6.7","Tissue RNA - liver [nTPM]":"6.0","Tissue RNA - lung [nTPM]":"10.5","Tissue RNA - lymph node [nTPM]":"12.4","Tissue RNA - medulla oblongata [nTPM]":"6.3","Tissue RNA - midbrain [nTPM]":"6.3","Tissue RNA - ovary [nTPM]":"21.2","Tissue RNA - pancreas [nTPM]":"11.1","Tissue RNA - parathyroid gland [nTPM]":"9.8","Tissue RNA - pituitary gland [nTPM]":"10.2","Tissue RNA - placenta [nTPM]":"5.6","Tissue RNA - pons [nTPM]":"6.6","Tissue RNA - prostate [nTPM]":"9.2","Tissue RNA - rectum [nTPM]":"6.4","Tissue RNA - retina [nTPM]":"23.9","Tissue RNA - salivary gland [nTPM]":"9.4","Tissue RNA - seminal vesicle [nTPM]":"8.4","Tissue RNA - skeletal muscle [nTPM]":"7.4","Tissue RNA - skin 1 [nTPM]":"10.4","Tissue RNA - small intestine [nTPM]":"9.8","Tissue RNA - smooth muscle [nTPM]":"7.6","Tissue RNA - spinal cord [nTPM]":"3.2","Tissue RNA - spleen [nTPM]":"9.7","Tissue RNA - stomach 1 [nTPM]":"8.2","Tissue RNA - testis [nTPM]":"5.3","Tissue RNA - thalamus [nTPM]":"7.0","Tissue RNA - thymus [nTPM]":"14.1","Tissue RNA - thyroid gland [nTPM]":"9.9","Tissue RNA - tongue [nTPM]":"8.4","Tissue RNA - tonsil [nTPM]":"11.3","Tissue RNA - urinary bladder [nTPM]":"10.7","Tissue RNA - vagina [nTPM]":"9.3","Tissue RNA - white matter [nTPM]":"11.9","Cell RNA - A-431 [nTPM]":"17.9","Cell RNA - A549 [nTPM]":"8.6","Cell RNA - AF22 [nTPM]":"20.1","Cell RNA - AN3-CA [nTPM]":"14.5","Cell RNA - ASC diff [nTPM]":"11.1","Cell RNA - ASC TERT1 [nTPM]":"16.1","Cell RNA - BEWO [nTPM]":"6.2","Cell RNA - BJ [nTPM]":"8.7","Cell RNA - BJ hTERT+ [nTPM]":"11.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.6","Cell RNA - CACO-2 [nTPM]":"17.3","Cell RNA - CAPAN-2 [nTPM]":"11.4","Cell RNA - Daudi [nTPM]":"23.1","Cell RNA - EFO-21 [nTPM]":"15.9","Cell RNA - fHDF\/TERT166 [nTPM]":"10.8","Cell RNA - GAMG [nTPM]":"14.6","Cell RNA - HaCaT [nTPM]":"16.0","Cell RNA - HAP1 [nTPM]":"22.9","Cell RNA - HBEC3-KT [nTPM]":"7.2","Cell RNA - HBF TERT88 [nTPM]":"17.9","Cell RNA - HDLM-2 [nTPM]":"26.0","Cell RNA - HEK 293 [nTPM]":"10.0","Cell RNA - HEL [nTPM]":"45.7","Cell RNA - HeLa [nTPM]":"8.9","Cell RNA - Hep G2 [nTPM]":"9.3","Cell RNA - HHSteC [nTPM]":"6.1","Cell RNA - HL-60 [nTPM]":"28.5","Cell RNA - HMC-1 [nTPM]":"7.8","Cell RNA - HSkMC [nTPM]":"7.2","Cell RNA - hTCEpi [nTPM]":"7.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.3","Cell RNA - hTERT-HME1 [nTPM]":"24.0","Cell RNA - hTERT-RPE1 [nTPM]":"8.9","Cell RNA - HUVEC TERT2 [nTPM]":"12.8","Cell RNA - JURKAT [nTPM]":"13.3","Cell RNA - K-562 [nTPM]":"32.8","Cell RNA - Karpas-707 [nTPM]":"18.8","Cell RNA - LHCN-M2 [nTPM]":"9.2","Cell RNA - MCF7 [nTPM]":"12.7","Cell RNA - MOLT-4 [nTPM]":"18.2","Cell RNA - NB-4 [nTPM]":"12.7","Cell RNA - NTERA-2 [nTPM]":"13.6","Cell RNA - OE19 [nTPM]":"6.6","Cell RNA - PC-3 [nTPM]":"13.7","Cell RNA - REH [nTPM]":"13.8","Cell RNA - RH-30 [nTPM]":"21.9","Cell RNA - RPMI-8226 [nTPM]":"6.9","Cell RNA - RPTEC TERT1 [nTPM]":"9.8","Cell RNA - RT4 [nTPM]":"13.8","Cell RNA - SCLC-21H [nTPM]":"18.0","Cell RNA - SH-SY5Y [nTPM]":"11.8","Cell RNA - SiHa [nTPM]":"22.0","Cell RNA - SK-BR-3 [nTPM]":"6.7","Cell RNA - SK-MEL-30 [nTPM]":"3.9","Cell RNA - SuSa [nTPM]":"9.8","Cell RNA - T-47d [nTPM]":"11.9","Cell RNA - THP-1 [nTPM]":"9.1","Cell RNA - TIME [nTPM]":"20.4","Cell RNA - U-138 MG [nTPM]":"14.1","Cell RNA - U-2 OS [nTPM]":"12.7","Cell RNA - U-2197 [nTPM]":"9.4","Cell RNA - U-251 MG [nTPM]":"14.7","Cell RNA - U-266\/70 [nTPM]":"5.1","Cell RNA - U-266\/84 [nTPM]":"4.4","Cell RNA - U-698 [nTPM]":"15.6","Cell RNA - U-87 MG [nTPM]":"4.7","Cell RNA - U-937 [nTPM]":"17.6","Cell RNA - WM-115 [nTPM]":"8.3","Blood RNA - basophil [nTPM]":"2.1","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"1.9","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"1.6","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.8","Blood RNA - memory CD8 T-cell [nTPM]":"1.5","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"1.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.2","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"2.0","Blood RNA - non-classical monocyte [nTPM]":"0.7","Blood RNA - plasmacytoid DC [nTPM]":"1.4","Blood RNA - T-reg [nTPM]":"1.7","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"8.0","Brain RNA - basal ganglia [nTPM]":"8.6","Brain RNA - cerebellum [nTPM]":"21.2","Brain RNA - cerebral cortex [nTPM]":"9.3","Brain RNA - hippocampal formation [nTPM]":"7.4","Brain RNA - hypothalamus [nTPM]":"9.6","Brain RNA - medulla oblongata [nTPM]":"6.3","Brain RNA - midbrain [nTPM]":"6.3","Brain RNA - pons [nTPM]":"6.6","Brain RNA - spinal cord [nTPM]":"3.2","Brain RNA - thalamus [nTPM]":"7.0","Brain RNA - white matter [nTPM]":"11.9","Single Cell Type RNA - Adipocytes [nTPM]":"87.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"70.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"65.8","Single Cell Type RNA - Astrocytes [nTPM]":"93.4","Single Cell Type RNA - B-cells [nTPM]":"83.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"86.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"67.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"64.9","Single Cell Type RNA - Bipolar cells [nTPM]":"158.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"76.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"73.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"44.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"40.0","Single Cell Type RNA - Club cells [nTPM]":"32.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"152.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.9","Single Cell Type RNA - dendritic cells [nTPM]":"81.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"26.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"33.0","Single Cell Type RNA - Early spermatids [nTPM]":"10.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"62.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"101.4","Single Cell Type RNA - Endothelial cells [nTPM]":"74.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"66.4","Single Cell Type RNA - Erythroid cells [nTPM]":"67.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"146.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.2","Single Cell Type RNA - Fibroblasts [nTPM]":"65.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"44.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"85.2","Single Cell Type RNA - granulocytes [nTPM]":"29.0","Single Cell Type RNA - Granulosa cells [nTPM]":"57.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"60.0","Single Cell Type RNA - Hepatocytes [nTPM]":"27.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.8","Single Cell Type RNA - Horizontal cells [nTPM]":"195.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"170.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"29.6","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"37.0","Single Cell Type RNA - Langerhans cells [nTPM]":"63.7","Single Cell Type RNA - Late spermatids [nTPM]":"5.8","Single Cell Type RNA - Leydig cells [nTPM]":"66.8","Single Cell Type RNA - Macrophages [nTPM]":"44.8","Single Cell Type RNA - Melanocytes [nTPM]":"42.7","Single Cell Type RNA - Microglial cells [nTPM]":"62.8","Single Cell Type RNA - monocytes [nTPM]":"49.9","Single Cell Type RNA - Muller glia cells [nTPM]":"98.9","Single Cell Type RNA - NK-cells [nTPM]":"78.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"106.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"131.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"28.2","Single Cell Type RNA - Paneth cells [nTPM]":"20.1","Single Cell Type RNA - Peritubular cells [nTPM]":"78.6","Single Cell Type RNA - Plasma cells [nTPM]":"83.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"88.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"52.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"152.4","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"113.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"84.6","Single Cell Type RNA - Spermatocytes [nTPM]":"25.5","Single Cell Type RNA - Spermatogonia [nTPM]":"30.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"46.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"80.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.0","Single Cell Type RNA - T-cells [nTPM]":"102.8","Single Cell Type RNA - Theca cells [nTPM]":"55.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"30.6","Single Cell Type RNA - Urothelial cells [nTPM]":"64.8"},{"Gene":"KMT2B","Gene synonym":["CXXC10","HRX2","KIAA0304","MLL1B","MLL2","MLL4","TRX2","WBP7"],"Ensembl":"ENSG00000272333","Gene description":"Lysine methyltransferase 2B","Uniprot":["Q9UMN6"],"Chromosome":"19","Position":"35717973-35738878","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Methyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Dystonia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"64.5","Rod photoreceptor cells":"71.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006487"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA006487":"AB_1080587"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.6","Tissue RNA - adrenal gland [nTPM]":"10.1","Tissue RNA - amygdala [nTPM]":"15.4","Tissue RNA - appendix [nTPM]":"9.8","Tissue RNA - basal ganglia [nTPM]":"15.7","Tissue RNA - bone marrow [nTPM]":"14.3","Tissue RNA - breast [nTPM]":"11.8","Tissue RNA - cerebellum [nTPM]":"17.2","Tissue RNA - cerebral cortex [nTPM]":"22.9","Tissue RNA - cervix [nTPM]":"12.9","Tissue RNA - choroid plexus [nTPM]":"12.2","Tissue RNA - colon [nTPM]":"13.6","Tissue RNA - duodenum [nTPM]":"9.8","Tissue RNA - endometrium 1 [nTPM]":"14.1","Tissue RNA - epididymis [nTPM]":"4.4","Tissue RNA - esophagus [nTPM]":"12.8","Tissue RNA - fallopian tube [nTPM]":"13.1","Tissue RNA - gallbladder [nTPM]":"6.8","Tissue RNA - heart muscle [nTPM]":"8.4","Tissue RNA - hippocampal formation [nTPM]":"14.7","Tissue RNA - hypothalamus [nTPM]":"14.8","Tissue RNA - kidney [nTPM]":"10.3","Tissue RNA - liver [nTPM]":"10.0","Tissue RNA - lung [nTPM]":"12.1","Tissue RNA - lymph node [nTPM]":"14.5","Tissue RNA - medulla oblongata [nTPM]":"15.4","Tissue RNA - midbrain [nTPM]":"14.4","Tissue RNA - ovary [nTPM]":"16.1","Tissue RNA - pancreas [nTPM]":"16.0","Tissue RNA - parathyroid gland [nTPM]":"5.1","Tissue RNA - pituitary gland [nTPM]":"14.5","Tissue RNA - placenta [nTPM]":"5.8","Tissue RNA - pons [nTPM]":"14.7","Tissue RNA - prostate [nTPM]":"13.4","Tissue RNA - rectum [nTPM]":"3.9","Tissue RNA - retina [nTPM]":"5.8","Tissue RNA - salivary gland [nTPM]":"13.3","Tissue RNA - seminal vesicle [nTPM]":"5.8","Tissue RNA - skeletal muscle [nTPM]":"16.1","Tissue RNA - skin 1 [nTPM]":"18.8","Tissue RNA - small intestine [nTPM]":"14.5","Tissue RNA - smooth muscle [nTPM]":"4.5","Tissue RNA - spinal cord [nTPM]":"12.4","Tissue RNA - spleen [nTPM]":"15.6","Tissue RNA - stomach 1 [nTPM]":"12.7","Tissue RNA - testis [nTPM]":"22.5","Tissue RNA - thalamus [nTPM]":"15.9","Tissue RNA - thymus [nTPM]":"9.3","Tissue RNA - thyroid gland [nTPM]":"16.6","Tissue RNA - tongue [nTPM]":"5.0","Tissue RNA - tonsil [nTPM]":"6.8","Tissue RNA - urinary bladder [nTPM]":"12.6","Tissue RNA - vagina [nTPM]":"12.0","Tissue RNA - white matter [nTPM]":"16.0","Cell RNA - A-431 [nTPM]":"16.7","Cell RNA - A549 [nTPM]":"36.7","Cell RNA - AF22 [nTPM]":"11.1","Cell RNA - AN3-CA [nTPM]":"17.3","Cell RNA - ASC diff [nTPM]":"6.0","Cell RNA - ASC TERT1 [nTPM]":"4.3","Cell RNA - BEWO [nTPM]":"11.0","Cell RNA - BJ [nTPM]":"6.7","Cell RNA - BJ hTERT+ [nTPM]":"4.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.0","Cell RNA - CACO-2 [nTPM]":"25.3","Cell RNA - CAPAN-2 [nTPM]":"7.4","Cell RNA - Daudi [nTPM]":"15.5","Cell RNA - EFO-21 [nTPM]":"11.8","Cell RNA - fHDF\/TERT166 [nTPM]":"5.1","Cell RNA - GAMG [nTPM]":"8.5","Cell RNA - HaCaT [nTPM]":"10.8","Cell RNA - HAP1 [nTPM]":"11.3","Cell RNA - HBEC3-KT [nTPM]":"5.2","Cell RNA - HBF TERT88 [nTPM]":"4.2","Cell RNA - HDLM-2 [nTPM]":"21.2","Cell RNA - HEK 293 [nTPM]":"13.6","Cell RNA - HEL [nTPM]":"29.7","Cell RNA - HeLa [nTPM]":"20.2","Cell RNA - Hep G2 [nTPM]":"24.4","Cell RNA - HHSteC [nTPM]":"8.6","Cell RNA - HL-60 [nTPM]":"17.4","Cell RNA - HMC-1 [nTPM]":"26.1","Cell RNA - HSkMC [nTPM]":"6.9","Cell RNA - hTCEpi [nTPM]":"9.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.9","Cell RNA - hTERT-HME1 [nTPM]":"10.7","Cell RNA - hTERT-RPE1 [nTPM]":"6.9","Cell RNA - HUVEC TERT2 [nTPM]":"5.7","Cell RNA - JURKAT [nTPM]":"13.5","Cell RNA - K-562 [nTPM]":"22.5","Cell RNA - Karpas-707 [nTPM]":"15.8","Cell RNA - LHCN-M2 [nTPM]":"6.4","Cell RNA - MCF7 [nTPM]":"34.1","Cell RNA - MOLT-4 [nTPM]":"15.9","Cell RNA - NB-4 [nTPM]":"24.4","Cell RNA - NTERA-2 [nTPM]":"12.0","Cell RNA - OE19 [nTPM]":"18.8","Cell RNA - PC-3 [nTPM]":"9.2","Cell RNA - REH [nTPM]":"19.8","Cell RNA - RH-30 [nTPM]":"8.9","Cell RNA - RPMI-8226 [nTPM]":"7.6","Cell RNA - RPTEC TERT1 [nTPM]":"7.8","Cell RNA - RT4 [nTPM]":"21.3","Cell RNA - SCLC-21H [nTPM]":"14.0","Cell RNA - SH-SY5Y [nTPM]":"10.0","Cell RNA - SiHa [nTPM]":"13.5","Cell RNA - SK-BR-3 [nTPM]":"20.6","Cell RNA - SK-MEL-30 [nTPM]":"11.3","Cell RNA - SuSa [nTPM]":"7.9","Cell RNA - T-47d [nTPM]":"11.8","Cell RNA - THP-1 [nTPM]":"21.3","Cell RNA - TIME [nTPM]":"12.5","Cell RNA - U-138 MG [nTPM]":"16.3","Cell RNA - U-2 OS [nTPM]":"17.0","Cell RNA - U-2197 [nTPM]":"10.5","Cell RNA - U-251 MG [nTPM]":"17.4","Cell RNA - U-266\/70 [nTPM]":"22.2","Cell RNA - U-266\/84 [nTPM]":"15.7","Cell RNA - U-698 [nTPM]":"12.4","Cell RNA - U-87 MG [nTPM]":"8.5","Cell RNA - U-937 [nTPM]":"18.8","Cell RNA - WM-115 [nTPM]":"12.2","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"2.1","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"15.4","Brain RNA - basal ganglia [nTPM]":"15.7","Brain RNA - cerebellum [nTPM]":"17.2","Brain RNA - cerebral cortex [nTPM]":"22.9","Brain RNA - hippocampal formation [nTPM]":"14.7","Brain RNA - hypothalamus [nTPM]":"14.8","Brain RNA - medulla oblongata [nTPM]":"15.4","Brain RNA - midbrain [nTPM]":"14.4","Brain RNA - pons [nTPM]":"14.7","Brain RNA - spinal cord [nTPM]":"12.4","Brain RNA - thalamus [nTPM]":"15.9","Brain RNA - white matter [nTPM]":"16.0","Single Cell Type RNA - Adipocytes [nTPM]":"24.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.4","Single Cell Type RNA - Astrocytes [nTPM]":"13.7","Single Cell Type RNA - B-cells [nTPM]":"18.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"64.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"6.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.5","Single Cell Type RNA - dendritic cells [nTPM]":"27.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"25.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.4","Single Cell Type RNA - Early spermatids [nTPM]":"2.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"31.6","Single Cell Type RNA - Endothelial cells [nTPM]":"15.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.3","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.1","Single Cell Type RNA - Fibroblasts [nTPM]":"12.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"27.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.0","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"30.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"11.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.4","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.1","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"11.8","Single Cell Type RNA - Langerhans cells [nTPM]":"7.1","Single Cell Type RNA - Late spermatids [nTPM]":"4.7","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"13.4","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"9.5","Single Cell Type RNA - Muller glia cells [nTPM]":"25.7","Single Cell Type RNA - NK-cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.4","Single Cell Type RNA - Paneth cells [nTPM]":"16.7","Single Cell Type RNA - Peritubular cells [nTPM]":"12.4","Single Cell Type RNA - Plasma cells [nTPM]":"17.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"71.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"25.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.3","Single Cell Type RNA - Spermatocytes [nTPM]":"26.5","Single Cell Type RNA - Spermatogonia [nTPM]":"38.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.4","Single Cell Type RNA - T-cells [nTPM]":"20.6","Single Cell Type RNA - Theca cells [nTPM]":"30.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.3","Single Cell Type RNA - Urothelial cells [nTPM]":"14.8"},{"Gene":"KMT2C","Gene synonym":["HALR","KIAA1506","MLL3"],"Ensembl":"ENSG00000055609","Gene description":"Lysine methyltransferase 2C","Uniprot":["Q8NEZ4"],"Chromosome":"7","Position":"152134922-152436641","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","Acyltransferase","Chromatin regulator","DNA-binding","Methyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"363.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"15.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074736"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA074736":"AB_2686709"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.01e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Tissue RNA - adipose tissue [nTPM]":"12.7","Tissue RNA - adrenal gland [nTPM]":"11.2","Tissue RNA - amygdala [nTPM]":"16.7","Tissue RNA - appendix [nTPM]":"7.3","Tissue RNA - basal ganglia [nTPM]":"25.7","Tissue RNA - bone marrow [nTPM]":"16.4","Tissue RNA - breast [nTPM]":"12.9","Tissue RNA - cerebellum [nTPM]":"16.7","Tissue RNA - cerebral cortex [nTPM]":"15.7","Tissue RNA - cervix [nTPM]":"15.3","Tissue RNA - choroid plexus [nTPM]":"5.5","Tissue RNA - colon [nTPM]":"13.1","Tissue RNA - duodenum [nTPM]":"5.7","Tissue RNA - endometrium 1 [nTPM]":"14.3","Tissue RNA - epididymis [nTPM]":"13.7","Tissue RNA - esophagus [nTPM]":"14.1","Tissue RNA - fallopian tube [nTPM]":"11.9","Tissue RNA - gallbladder [nTPM]":"7.7","Tissue RNA - heart muscle [nTPM]":"10.2","Tissue RNA - hippocampal formation [nTPM]":"13.0","Tissue RNA - hypothalamus [nTPM]":"18.9","Tissue RNA - kidney [nTPM]":"8.9","Tissue RNA - liver [nTPM]":"10.4","Tissue RNA - lung [nTPM]":"12.7","Tissue RNA - lymph node [nTPM]":"8.1","Tissue RNA - medulla oblongata [nTPM]":"25.3","Tissue RNA - midbrain [nTPM]":"19.4","Tissue RNA - ovary [nTPM]":"16.8","Tissue RNA - pancreas [nTPM]":"18.5","Tissue RNA - parathyroid gland [nTPM]":"12.4","Tissue RNA - pituitary gland [nTPM]":"12.1","Tissue RNA - placenta [nTPM]":"10.3","Tissue RNA - pons [nTPM]":"20.6","Tissue RNA - prostate [nTPM]":"9.3","Tissue RNA - rectum [nTPM]":"7.6","Tissue RNA - retina [nTPM]":"21.7","Tissue RNA - salivary gland [nTPM]":"14.2","Tissue RNA - seminal vesicle [nTPM]":"9.0","Tissue RNA - skeletal muscle [nTPM]":"25.9","Tissue RNA - skin 1 [nTPM]":"17.6","Tissue RNA - small intestine [nTPM]":"12.8","Tissue RNA - smooth muscle [nTPM]":"7.5","Tissue RNA - spinal cord [nTPM]":"12.2","Tissue RNA - spleen [nTPM]":"12.2","Tissue RNA - stomach 1 [nTPM]":"15.2","Tissue RNA - testis [nTPM]":"13.4","Tissue RNA - thalamus [nTPM]":"19.1","Tissue RNA - thymus [nTPM]":"16.1","Tissue RNA - thyroid gland [nTPM]":"14.6","Tissue RNA - tongue [nTPM]":"16.9","Tissue RNA - tonsil [nTPM]":"9.5","Tissue RNA - urinary bladder [nTPM]":"11.3","Tissue RNA - vagina [nTPM]":"12.7","Tissue RNA - white matter [nTPM]":"28.6","Cell RNA - A-431 [nTPM]":"13.4","Cell RNA - A549 [nTPM]":"6.1","Cell RNA - AF22 [nTPM]":"11.6","Cell RNA - AN3-CA [nTPM]":"11.7","Cell RNA - ASC diff [nTPM]":"19.0","Cell RNA - ASC TERT1 [nTPM]":"13.9","Cell RNA - BEWO [nTPM]":"10.2","Cell RNA - BJ [nTPM]":"4.7","Cell RNA - BJ hTERT+ [nTPM]":"6.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.5","Cell RNA - CACO-2 [nTPM]":"10.9","Cell RNA - CAPAN-2 [nTPM]":"4.7","Cell RNA - Daudi [nTPM]":"22.4","Cell RNA - EFO-21 [nTPM]":"8.9","Cell RNA - fHDF\/TERT166 [nTPM]":"11.3","Cell RNA - GAMG [nTPM]":"9.2","Cell RNA - HaCaT [nTPM]":"5.2","Cell RNA - HAP1 [nTPM]":"14.3","Cell RNA - HBEC3-KT [nTPM]":"7.5","Cell RNA - HBF TERT88 [nTPM]":"9.2","Cell RNA - HDLM-2 [nTPM]":"12.7","Cell RNA - HEK 293 [nTPM]":"6.5","Cell RNA - HEL [nTPM]":"14.0","Cell RNA - HeLa [nTPM]":"7.3","Cell RNA - Hep G2 [nTPM]":"4.5","Cell RNA - HHSteC [nTPM]":"8.9","Cell RNA - HL-60 [nTPM]":"22.9","Cell RNA - HMC-1 [nTPM]":"12.8","Cell RNA - HSkMC [nTPM]":"6.6","Cell RNA - hTCEpi [nTPM]":"9.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.1","Cell RNA - hTERT-HME1 [nTPM]":"8.2","Cell RNA - hTERT-RPE1 [nTPM]":"7.2","Cell RNA - HUVEC TERT2 [nTPM]":"8.4","Cell RNA - JURKAT [nTPM]":"9.7","Cell RNA - K-562 [nTPM]":"22.5","Cell RNA - Karpas-707 [nTPM]":"15.0","Cell RNA - LHCN-M2 [nTPM]":"11.7","Cell RNA - MCF7 [nTPM]":"12.7","Cell RNA - MOLT-4 [nTPM]":"14.8","Cell RNA - NB-4 [nTPM]":"11.1","Cell RNA - NTERA-2 [nTPM]":"6.8","Cell RNA - OE19 [nTPM]":"8.5","Cell RNA - PC-3 [nTPM]":"7.9","Cell RNA - REH [nTPM]":"9.5","Cell RNA - RH-30 [nTPM]":"12.3","Cell RNA - RPMI-8226 [nTPM]":"8.4","Cell RNA - RPTEC TERT1 [nTPM]":"5.8","Cell RNA - RT4 [nTPM]":"10.9","Cell RNA - SCLC-21H [nTPM]":"19.6","Cell RNA - SH-SY5Y [nTPM]":"12.8","Cell RNA - SiHa [nTPM]":"13.4","Cell RNA - SK-BR-3 [nTPM]":"15.8","Cell RNA - SK-MEL-30 [nTPM]":"6.3","Cell RNA - SuSa [nTPM]":"10.6","Cell RNA - T-47d [nTPM]":"4.6","Cell RNA - THP-1 [nTPM]":"15.7","Cell RNA - TIME [nTPM]":"12.8","Cell RNA - U-138 MG [nTPM]":"8.0","Cell RNA - U-2 OS [nTPM]":"4.4","Cell RNA - U-2197 [nTPM]":"9.0","Cell RNA - U-251 MG [nTPM]":"8.9","Cell RNA - U-266\/70 [nTPM]":"15.3","Cell RNA - U-266\/84 [nTPM]":"7.7","Cell RNA - U-698 [nTPM]":"22.4","Cell RNA - U-87 MG [nTPM]":"10.7","Cell RNA - U-937 [nTPM]":"14.7","Cell RNA - WM-115 [nTPM]":"8.4","Blood RNA - basophil [nTPM]":"6.1","Blood RNA - classical monocyte [nTPM]":"3.0","Blood RNA - eosinophil [nTPM]":"4.4","Blood RNA - gdT-cell [nTPM]":"1.9","Blood RNA - intermediate monocyte [nTPM]":"2.7","Blood RNA - MAIT T-cell [nTPM]":"1.6","Blood RNA - memory B-cell [nTPM]":"6.9","Blood RNA - memory CD4 T-cell [nTPM]":"2.0","Blood RNA - memory CD8 T-cell [nTPM]":"1.5","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"3.9","Blood RNA - naive CD4 T-cell [nTPM]":"1.9","Blood RNA - naive CD8 T-cell [nTPM]":"1.4","Blood RNA - neutrophil [nTPM]":"15.2","Blood RNA - NK-cell [nTPM]":"2.2","Blood RNA - non-classical monocyte [nTPM]":"2.6","Blood RNA - plasmacytoid DC [nTPM]":"3.7","Blood RNA - T-reg [nTPM]":"1.3","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"16.7","Brain RNA - basal ganglia [nTPM]":"25.7","Brain RNA - cerebellum [nTPM]":"16.7","Brain RNA - cerebral cortex [nTPM]":"15.7","Brain RNA - hippocampal formation [nTPM]":"13.0","Brain RNA - hypothalamus [nTPM]":"18.9","Brain RNA - medulla oblongata [nTPM]":"25.3","Brain RNA - midbrain [nTPM]":"19.4","Brain RNA - pons [nTPM]":"20.6","Brain RNA - spinal cord [nTPM]":"12.2","Brain RNA - thalamus [nTPM]":"19.1","Brain RNA - white matter [nTPM]":"28.6","Single Cell Type RNA - Adipocytes [nTPM]":"62.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"76.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"71.9","Single Cell Type RNA - Astrocytes [nTPM]":"292.8","Single Cell Type RNA - B-cells [nTPM]":"75.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"89.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"38.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"31.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"62.0","Single Cell Type RNA - Bipolar cells [nTPM]":"89.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"59.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"35.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"65.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"44.3","Single Cell Type RNA - Club cells [nTPM]":"72.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"46.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"173.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"38.0","Single Cell Type RNA - dendritic cells [nTPM]":"61.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"61.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"37.6","Single Cell Type RNA - Early spermatids [nTPM]":"32.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"94.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"92.1","Single Cell Type RNA - Endothelial cells [nTPM]":"58.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"67.9","Single Cell Type RNA - Erythroid cells [nTPM]":"55.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"180.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"33.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"51.7","Single Cell Type RNA - Fibroblasts [nTPM]":"58.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"89.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"200.5","Single Cell Type RNA - granulocytes [nTPM]":"65.2","Single Cell Type RNA - Granulosa cells [nTPM]":"52.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"56.7","Single Cell Type RNA - Hepatocytes [nTPM]":"46.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"33.7","Single Cell Type RNA - Horizontal cells [nTPM]":"80.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"172.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"53.5","Single Cell Type RNA - Ionocytes [nTPM]":"42.7","Single Cell Type RNA - Kupffer cells [nTPM]":"54.7","Single Cell Type RNA - Langerhans cells [nTPM]":"79.6","Single Cell Type RNA - Late spermatids [nTPM]":"17.3","Single Cell Type RNA - Leydig cells [nTPM]":"67.4","Single Cell Type RNA - Macrophages [nTPM]":"90.5","Single Cell Type RNA - Melanocytes [nTPM]":"42.7","Single Cell Type RNA - Microglial cells [nTPM]":"202.4","Single Cell Type RNA - monocytes [nTPM]":"77.1","Single Cell Type RNA - Muller glia cells [nTPM]":"57.7","Single Cell Type RNA - NK-cells [nTPM]":"59.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"299.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"363.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"37.6","Single Cell Type RNA - Paneth cells [nTPM]":"49.0","Single Cell Type RNA - Peritubular cells [nTPM]":"60.2","Single Cell Type RNA - Plasma cells [nTPM]":"90.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"53.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"36.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"46.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"73.0","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"83.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"55.5","Single Cell Type RNA - Spermatocytes [nTPM]":"42.3","Single Cell Type RNA - Spermatogonia [nTPM]":"33.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"80.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"96.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"127.2","Single Cell Type RNA - T-cells [nTPM]":"76.8","Single Cell Type RNA - Theca cells [nTPM]":"54.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"39.1","Single Cell Type RNA - Urothelial cells [nTPM]":"61.4"},{"Gene":"KMT2D","Gene synonym":["ALR","CAGL114","MLL2","MLL4","TNRC21"],"Ensembl":"ENSG00000167548","Gene description":"Lysine methyltransferase 2D","Uniprot":["O14686"],"Chromosome":"12","Position":"49018978-49060794","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","Methyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035977"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm","Plasma membrane"],"Antibody RRID":{"HPA035977":"AB_10670673"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-2"},"Tissue RNA - adipose tissue [nTPM]":"19.9","Tissue RNA - adrenal gland [nTPM]":"21.9","Tissue RNA - amygdala [nTPM]":"14.0","Tissue RNA - appendix [nTPM]":"17.0","Tissue RNA - basal ganglia [nTPM]":"14.4","Tissue RNA - bone marrow [nTPM]":"62.1","Tissue RNA - breast [nTPM]":"20.3","Tissue RNA - cerebellum [nTPM]":"14.7","Tissue RNA - cerebral cortex [nTPM]":"18.1","Tissue RNA - cervix [nTPM]":"20.2","Tissue RNA - choroid plexus [nTPM]":"3.8","Tissue RNA - colon [nTPM]":"21.3","Tissue RNA - duodenum [nTPM]":"13.2","Tissue RNA - endometrium 1 [nTPM]":"26.9","Tissue RNA - epididymis [nTPM]":"14.4","Tissue RNA - esophagus [nTPM]":"25.5","Tissue RNA - fallopian tube [nTPM]":"24.1","Tissue RNA - gallbladder [nTPM]":"11.7","Tissue RNA - heart muscle [nTPM]":"23.7","Tissue RNA - hippocampal formation [nTPM]":"12.1","Tissue RNA - hypothalamus [nTPM]":"9.1","Tissue RNA - kidney [nTPM]":"18.2","Tissue RNA - liver [nTPM]":"20.5","Tissue RNA - lung [nTPM]":"25.1","Tissue RNA - lymph node [nTPM]":"17.5","Tissue RNA - medulla oblongata [nTPM]":"9.3","Tissue RNA - midbrain [nTPM]":"8.2","Tissue RNA - ovary [nTPM]":"25.3","Tissue RNA - pancreas [nTPM]":"33.2","Tissue RNA - parathyroid gland [nTPM]":"22.9","Tissue RNA - pituitary gland [nTPM]":"25.4","Tissue RNA - placenta [nTPM]":"16.2","Tissue RNA - pons [nTPM]":"8.6","Tissue RNA - prostate [nTPM]":"19.2","Tissue RNA - rectum [nTPM]":"14.7","Tissue RNA - retina [nTPM]":"48.0","Tissue RNA - salivary gland [nTPM]":"22.1","Tissue RNA - seminal vesicle [nTPM]":"16.2","Tissue RNA - skeletal muscle [nTPM]":"44.9","Tissue RNA - skin 1 [nTPM]":"30.4","Tissue RNA - small intestine [nTPM]":"27.9","Tissue RNA - smooth muscle [nTPM]":"15.5","Tissue RNA - spinal cord [nTPM]":"3.1","Tissue RNA - spleen [nTPM]":"36.6","Tissue RNA - stomach 1 [nTPM]":"25.5","Tissue RNA - testis [nTPM]":"23.6","Tissue RNA - thalamus [nTPM]":"12.7","Tissue RNA - thymus [nTPM]":"29.0","Tissue RNA - thyroid gland [nTPM]":"26.5","Tissue RNA - tongue [nTPM]":"21.9","Tissue RNA - tonsil [nTPM]":"17.2","Tissue RNA - urinary bladder [nTPM]":"19.4","Tissue RNA - vagina [nTPM]":"19.4","Tissue RNA - white matter [nTPM]":"13.4","Cell RNA - A-431 [nTPM]":"32.3","Cell RNA - A549 [nTPM]":"31.9","Cell RNA - AF22 [nTPM]":"31.0","Cell RNA - AN3-CA [nTPM]":"24.7","Cell RNA - ASC diff [nTPM]":"29.3","Cell RNA - ASC TERT1 [nTPM]":"20.4","Cell RNA - BEWO [nTPM]":"32.6","Cell RNA - BJ [nTPM]":"17.3","Cell RNA - BJ hTERT+ [nTPM]":"17.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.9","Cell RNA - CACO-2 [nTPM]":"54.8","Cell RNA - CAPAN-2 [nTPM]":"14.1","Cell RNA - Daudi [nTPM]":"33.4","Cell RNA - EFO-21 [nTPM]":"21.2","Cell RNA - fHDF\/TERT166 [nTPM]":"23.9","Cell RNA - GAMG [nTPM]":"14.0","Cell RNA - HaCaT [nTPM]":"21.5","Cell RNA - HAP1 [nTPM]":"38.1","Cell RNA - HBEC3-KT [nTPM]":"19.9","Cell RNA - HBF TERT88 [nTPM]":"17.7","Cell RNA - HDLM-2 [nTPM]":"22.4","Cell RNA - HEK 293 [nTPM]":"26.7","Cell RNA - HEL [nTPM]":"47.2","Cell RNA - HeLa [nTPM]":"37.7","Cell RNA - Hep G2 [nTPM]":"29.9","Cell RNA - HHSteC [nTPM]":"20.5","Cell RNA - HL-60 [nTPM]":"59.1","Cell RNA - HMC-1 [nTPM]":"43.2","Cell RNA - HSkMC [nTPM]":"18.4","Cell RNA - hTCEpi [nTPM]":"25.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"30.7","Cell RNA - hTERT-HME1 [nTPM]":"32.0","Cell RNA - hTERT-RPE1 [nTPM]":"27.3","Cell RNA - HUVEC TERT2 [nTPM]":"31.8","Cell RNA - JURKAT [nTPM]":"33.2","Cell RNA - K-562 [nTPM]":"55.1","Cell RNA - Karpas-707 [nTPM]":"19.2","Cell RNA - LHCN-M2 [nTPM]":"23.7","Cell RNA - MCF7 [nTPM]":"37.4","Cell RNA - MOLT-4 [nTPM]":"26.8","Cell RNA - NB-4 [nTPM]":"48.0","Cell RNA - NTERA-2 [nTPM]":"29.9","Cell RNA - OE19 [nTPM]":"45.4","Cell RNA - PC-3 [nTPM]":"25.0","Cell RNA - REH [nTPM]":"37.4","Cell RNA - RH-30 [nTPM]":"22.4","Cell RNA - RPMI-8226 [nTPM]":"12.0","Cell RNA - RPTEC TERT1 [nTPM]":"18.1","Cell RNA - RT4 [nTPM]":"37.2","Cell RNA - SCLC-21H [nTPM]":"24.6","Cell RNA - SH-SY5Y [nTPM]":"21.2","Cell RNA - SiHa [nTPM]":"28.1","Cell RNA - SK-BR-3 [nTPM]":"25.5","Cell RNA - SK-MEL-30 [nTPM]":"19.5","Cell RNA - SuSa [nTPM]":"26.1","Cell RNA - T-47d [nTPM]":"24.0","Cell RNA - THP-1 [nTPM]":"44.1","Cell RNA - TIME [nTPM]":"49.8","Cell RNA - U-138 MG [nTPM]":"15.5","Cell RNA - U-2 OS [nTPM]":"30.7","Cell RNA - U-2197 [nTPM]":"14.5","Cell RNA - U-251 MG [nTPM]":"30.5","Cell RNA - U-266\/70 [nTPM]":"24.8","Cell RNA - U-266\/84 [nTPM]":"20.9","Cell RNA - U-698 [nTPM]":"31.7","Cell RNA - U-87 MG [nTPM]":"17.1","Cell RNA - U-937 [nTPM]":"28.0","Cell RNA - WM-115 [nTPM]":"12.5","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"1.5","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"14.0","Brain RNA - basal ganglia [nTPM]":"14.4","Brain RNA - cerebellum [nTPM]":"14.7","Brain RNA - cerebral cortex [nTPM]":"18.1","Brain RNA - hippocampal formation [nTPM]":"12.1","Brain RNA - hypothalamus [nTPM]":"9.1","Brain RNA - medulla oblongata [nTPM]":"9.3","Brain RNA - midbrain [nTPM]":"8.2","Brain RNA - pons [nTPM]":"8.6","Brain RNA - spinal cord [nTPM]":"3.1","Brain RNA - thalamus [nTPM]":"12.7","Brain RNA - white matter [nTPM]":"13.4","Single Cell Type RNA - Adipocytes [nTPM]":"12.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.1","Single Cell Type RNA - Astrocytes [nTPM]":"17.6","Single Cell Type RNA - B-cells [nTPM]":"13.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"26.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"10.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.2","Single Cell Type RNA - dendritic cells [nTPM]":"15.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.3","Single Cell Type RNA - Early spermatids [nTPM]":"2.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.7","Single Cell Type RNA - Endothelial cells [nTPM]":"13.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"16.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.0","Single Cell Type RNA - Fibroblasts [nTPM]":"8.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"24.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.1","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"23.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.9","Single Cell Type RNA - Hepatocytes [nTPM]":"13.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.8","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"16.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"15.7","Single Cell Type RNA - Langerhans cells [nTPM]":"18.4","Single Cell Type RNA - Late spermatids [nTPM]":"2.4","Single Cell Type RNA - Leydig cells [nTPM]":"9.6","Single Cell Type RNA - Macrophages [nTPM]":"15.4","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"14.9","Single Cell Type RNA - Muller glia cells [nTPM]":"6.4","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.8","Single Cell Type RNA - Paneth cells [nTPM]":"9.5","Single Cell Type RNA - Peritubular cells [nTPM]":"10.9","Single Cell Type RNA - Plasma cells [nTPM]":"10.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"38.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.5","Single Cell Type RNA - Spermatocytes [nTPM]":"6.5","Single Cell Type RNA - Spermatogonia [nTPM]":"3.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.4","Single Cell Type RNA - T-cells [nTPM]":"15.3","Single Cell Type RNA - Theca cells [nTPM]":"10.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.3","Single Cell Type RNA - Urothelial cells [nTPM]":"9.6"},{"Gene":"KMT5B","Gene synonym":["CGI-85","SUV420H1"],"Ensembl":"ENSG00000110066","Gene description":"Lysine methyltransferase 5B","Uniprot":["Q4FZB7"],"Chromosome":"11","Position":"68154863-68213828","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Myogenesis","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","Methyltransferase","Repressor","Transferase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SK-MEL-30":"128.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063648"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA063648":"AB_2685073"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.30e-4"},"Tissue RNA - adipose tissue [nTPM]":"18.6","Tissue RNA - adrenal gland [nTPM]":"16.5","Tissue RNA - amygdala [nTPM]":"16.3","Tissue RNA - appendix [nTPM]":"15.7","Tissue RNA - basal ganglia [nTPM]":"17.5","Tissue RNA - bone marrow [nTPM]":"28.5","Tissue RNA - breast [nTPM]":"27.5","Tissue RNA - cerebellum [nTPM]":"26.2","Tissue RNA - cerebral cortex [nTPM]":"17.6","Tissue RNA - cervix [nTPM]":"20.2","Tissue RNA - choroid plexus [nTPM]":"17.3","Tissue RNA - colon [nTPM]":"22.3","Tissue RNA - duodenum [nTPM]":"22.8","Tissue RNA - endometrium 1 [nTPM]":"26.2","Tissue RNA - epididymis [nTPM]":"19.0","Tissue RNA - esophagus [nTPM]":"17.2","Tissue RNA - fallopian tube [nTPM]":"18.2","Tissue RNA - gallbladder [nTPM]":"15.0","Tissue RNA - heart muscle [nTPM]":"15.9","Tissue RNA - hippocampal formation [nTPM]":"15.8","Tissue RNA - hypothalamus [nTPM]":"17.2","Tissue RNA - kidney [nTPM]":"19.7","Tissue RNA - liver [nTPM]":"22.4","Tissue RNA - lung [nTPM]":"18.1","Tissue RNA - lymph node [nTPM]":"19.2","Tissue RNA - medulla oblongata [nTPM]":"16.1","Tissue RNA - midbrain [nTPM]":"16.3","Tissue RNA - ovary [nTPM]":"22.4","Tissue RNA - pancreas [nTPM]":"22.8","Tissue RNA - parathyroid gland [nTPM]":"20.6","Tissue RNA - pituitary gland [nTPM]":"15.6","Tissue RNA - placenta [nTPM]":"22.3","Tissue RNA - pons [nTPM]":"15.6","Tissue RNA - prostate [nTPM]":"22.0","Tissue RNA - rectum [nTPM]":"21.6","Tissue RNA - retina [nTPM]":"33.4","Tissue RNA - salivary gland [nTPM]":"23.4","Tissue RNA - seminal vesicle [nTPM]":"16.3","Tissue RNA - skeletal muscle [nTPM]":"16.9","Tissue RNA - skin 1 [nTPM]":"21.7","Tissue RNA - small intestine [nTPM]":"21.8","Tissue RNA - smooth muscle [nTPM]":"20.7","Tissue RNA - spinal cord [nTPM]":"14.8","Tissue RNA - spleen [nTPM]":"17.2","Tissue RNA - stomach 1 [nTPM]":"20.7","Tissue RNA - testis [nTPM]":"20.7","Tissue RNA - thalamus [nTPM]":"16.1","Tissue RNA - thymus [nTPM]":"27.0","Tissue RNA - thyroid gland [nTPM]":"31.0","Tissue RNA - tongue [nTPM]":"16.7","Tissue RNA - tonsil [nTPM]":"20.4","Tissue RNA - urinary bladder [nTPM]":"16.5","Tissue RNA - vagina [nTPM]":"17.6","Tissue RNA - white matter [nTPM]":"21.3","Cell RNA - A-431 [nTPM]":"25.3","Cell RNA - A549 [nTPM]":"18.8","Cell RNA - AF22 [nTPM]":"37.6","Cell RNA - AN3-CA [nTPM]":"24.5","Cell RNA - ASC diff [nTPM]":"8.6","Cell RNA - ASC TERT1 [nTPM]":"21.4","Cell RNA - BEWO [nTPM]":"40.8","Cell RNA - BJ [nTPM]":"17.7","Cell RNA - BJ hTERT+ [nTPM]":"12.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.8","Cell RNA - CACO-2 [nTPM]":"59.7","Cell RNA - CAPAN-2 [nTPM]":"39.6","Cell RNA - Daudi [nTPM]":"20.5","Cell RNA - EFO-21 [nTPM]":"30.2","Cell RNA - fHDF\/TERT166 [nTPM]":"24.4","Cell RNA - GAMG [nTPM]":"21.4","Cell RNA - HaCaT [nTPM]":"13.0","Cell RNA - HAP1 [nTPM]":"26.2","Cell RNA - HBEC3-KT [nTPM]":"20.6","Cell RNA - HBF TERT88 [nTPM]":"31.6","Cell RNA - HDLM-2 [nTPM]":"23.2","Cell RNA - HEK 293 [nTPM]":"15.1","Cell RNA - HEL [nTPM]":"19.4","Cell RNA - HeLa [nTPM]":"21.9","Cell RNA - Hep G2 [nTPM]":"24.7","Cell RNA - HHSteC [nTPM]":"31.0","Cell RNA - HL-60 [nTPM]":"27.7","Cell RNA - HMC-1 [nTPM]":"25.6","Cell RNA - HSkMC [nTPM]":"21.3","Cell RNA - hTCEpi [nTPM]":"41.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.2","Cell RNA - hTERT-HME1 [nTPM]":"27.3","Cell RNA - hTERT-RPE1 [nTPM]":"20.0","Cell RNA - HUVEC TERT2 [nTPM]":"21.8","Cell RNA - JURKAT [nTPM]":"20.3","Cell RNA - K-562 [nTPM]":"29.3","Cell RNA - Karpas-707 [nTPM]":"23.4","Cell RNA - LHCN-M2 [nTPM]":"18.7","Cell RNA - MCF7 [nTPM]":"52.2","Cell RNA - MOLT-4 [nTPM]":"19.6","Cell RNA - NB-4 [nTPM]":"28.9","Cell RNA - NTERA-2 [nTPM]":"40.4","Cell RNA - OE19 [nTPM]":"50.4","Cell RNA - PC-3 [nTPM]":"13.9","Cell RNA - REH [nTPM]":"31.9","Cell RNA - RH-30 [nTPM]":"29.4","Cell RNA - RPMI-8226 [nTPM]":"55.4","Cell RNA - RPTEC TERT1 [nTPM]":"16.2","Cell RNA - RT4 [nTPM]":"24.2","Cell RNA - SCLC-21H [nTPM]":"32.7","Cell RNA - SH-SY5Y [nTPM]":"39.1","Cell RNA - SiHa [nTPM]":"27.5","Cell RNA - SK-BR-3 [nTPM]":"27.4","Cell RNA - SK-MEL-30 [nTPM]":"128.7","Cell RNA - SuSa [nTPM]":"20.3","Cell RNA - T-47d [nTPM]":"35.1","Cell RNA - THP-1 [nTPM]":"17.9","Cell RNA - TIME [nTPM]":"23.1","Cell RNA - U-138 MG [nTPM]":"29.2","Cell RNA - U-2 OS [nTPM]":"38.9","Cell RNA - U-2197 [nTPM]":"22.5","Cell RNA - U-251 MG [nTPM]":"18.4","Cell RNA - U-266\/70 [nTPM]":"29.5","Cell RNA - U-266\/84 [nTPM]":"13.8","Cell RNA - U-698 [nTPM]":"43.0","Cell RNA - U-87 MG [nTPM]":"18.4","Cell RNA - U-937 [nTPM]":"17.3","Cell RNA - WM-115 [nTPM]":"31.8","Blood RNA - basophil [nTPM]":"10.0","Blood RNA - classical monocyte [nTPM]":"3.7","Blood RNA - eosinophil [nTPM]":"16.5","Blood RNA - gdT-cell [nTPM]":"4.4","Blood RNA - intermediate monocyte [nTPM]":"5.2","Blood RNA - MAIT T-cell [nTPM]":"3.1","Blood RNA - memory B-cell [nTPM]":"3.2","Blood RNA - memory CD4 T-cell [nTPM]":"4.6","Blood RNA - memory CD8 T-cell [nTPM]":"5.4","Blood RNA - myeloid DC [nTPM]":"3.5","Blood RNA - naive B-cell [nTPM]":"3.8","Blood RNA - naive CD4 T-cell [nTPM]":"5.3","Blood RNA - naive CD8 T-cell [nTPM]":"4.8","Blood RNA - neutrophil [nTPM]":"10.9","Blood RNA - NK-cell [nTPM]":"9.6","Blood RNA - non-classical monocyte [nTPM]":"5.3","Blood RNA - plasmacytoid DC [nTPM]":"5.4","Blood RNA - T-reg [nTPM]":"4.1","Blood RNA - total PBMC [nTPM]":"2.8","Brain RNA - amygdala [nTPM]":"16.3","Brain RNA - basal ganglia [nTPM]":"17.5","Brain RNA - cerebellum [nTPM]":"26.2","Brain RNA - cerebral cortex [nTPM]":"17.6","Brain RNA - hippocampal formation [nTPM]":"15.8","Brain RNA - hypothalamus [nTPM]":"17.2","Brain RNA - medulla oblongata [nTPM]":"16.1","Brain RNA - midbrain [nTPM]":"16.3","Brain RNA - pons [nTPM]":"15.6","Brain RNA - spinal cord [nTPM]":"14.8","Brain RNA - thalamus [nTPM]":"16.1","Brain RNA - white matter [nTPM]":"21.3","Single Cell Type RNA - Adipocytes [nTPM]":"39.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"61.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"32.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"42.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"50.7","Single Cell Type RNA - Bipolar cells [nTPM]":"50.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"45.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"34.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"25.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.4","Single Cell Type RNA - dendritic cells [nTPM]":"37.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"32.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"27.9","Single Cell Type RNA - Early spermatids [nTPM]":"22.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"42.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"46.3","Single Cell Type RNA - Endothelial cells [nTPM]":"31.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"25.5","Single Cell Type RNA - Erythroid cells [nTPM]":"31.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"32.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"29.6","Single Cell Type RNA - Fibroblasts [nTPM]":"26.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"37.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"44.3","Single Cell Type RNA - granulocytes [nTPM]":"22.7","Single Cell Type RNA - Granulosa cells [nTPM]":"40.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"30.0","Single Cell Type RNA - Hepatocytes [nTPM]":"37.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.9","Single Cell Type RNA - Horizontal cells [nTPM]":"63.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"32.4","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"21.0","Single Cell Type RNA - Leydig cells [nTPM]":"28.0","Single Cell Type RNA - Macrophages [nTPM]":"27.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"38.2","Single Cell Type RNA - Muller glia cells [nTPM]":"29.6","Single Cell Type RNA - NK-cells [nTPM]":"43.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"37.1","Single Cell Type RNA - Paneth cells [nTPM]":"25.7","Single Cell Type RNA - Peritubular cells [nTPM]":"31.6","Single Cell Type RNA - Plasma cells [nTPM]":"34.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"43.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"36.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"32.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"44.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"28.6","Single Cell Type RNA - Spermatocytes [nTPM]":"45.8","Single Cell Type RNA - Spermatogonia [nTPM]":"58.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"38.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"51.7","Single Cell Type RNA - T-cells [nTPM]":"30.7","Single Cell Type RNA - Theca cells [nTPM]":"31.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"25.1","Single Cell Type RNA - Urothelial cells [nTPM]":"53.6"},{"Gene":"KRAS","Gene synonym":["KRAS1","KRAS2"],"Ensembl":"ENSG00000133703","Gene description":"KRAS proto-oncogene, GTPase","Uniprot":["P01116"],"Chromosome":"12","Position":"25205246-25250936","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes","Cardiomyopathy","Deafness","Disease variant","Ectodermal dysplasia","Mental retardation","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049830"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3300000","Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049830":"AB_2680903"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.59e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.75e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.97e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.8","Tissue RNA - adrenal gland [nTPM]":"9.1","Tissue RNA - amygdala [nTPM]":"11.0","Tissue RNA - appendix [nTPM]":"16.2","Tissue RNA - basal ganglia [nTPM]":"12.2","Tissue RNA - bone marrow [nTPM]":"27.8","Tissue RNA - breast [nTPM]":"10.0","Tissue RNA - cerebellum [nTPM]":"11.7","Tissue RNA - cerebral cortex [nTPM]":"12.3","Tissue RNA - cervix [nTPM]":"9.5","Tissue RNA - choroid plexus [nTPM]":"4.6","Tissue RNA - colon [nTPM]":"22.0","Tissue RNA - duodenum [nTPM]":"14.0","Tissue RNA - endometrium 1 [nTPM]":"11.0","Tissue RNA - epididymis [nTPM]":"6.8","Tissue RNA - esophagus [nTPM]":"19.3","Tissue RNA - fallopian tube [nTPM]":"7.4","Tissue RNA - gallbladder [nTPM]":"13.1","Tissue RNA - heart muscle [nTPM]":"8.6","Tissue RNA - hippocampal formation [nTPM]":"12.5","Tissue RNA - hypothalamus [nTPM]":"12.0","Tissue RNA - kidney [nTPM]":"11.7","Tissue RNA - liver [nTPM]":"15.3","Tissue RNA - lung [nTPM]":"13.2","Tissue RNA - lymph node [nTPM]":"17.9","Tissue RNA - medulla oblongata [nTPM]":"8.5","Tissue RNA - midbrain [nTPM]":"9.7","Tissue RNA - ovary [nTPM]":"8.0","Tissue RNA - pancreas [nTPM]":"12.6","Tissue RNA - parathyroid gland [nTPM]":"11.1","Tissue RNA - pituitary gland [nTPM]":"5.7","Tissue RNA - placenta [nTPM]":"17.0","Tissue RNA - pons [nTPM]":"8.7","Tissue RNA - prostate [nTPM]":"11.8","Tissue RNA - rectum [nTPM]":"23.0","Tissue RNA - retina [nTPM]":"22.7","Tissue RNA - salivary gland [nTPM]":"11.9","Tissue RNA - seminal vesicle [nTPM]":"8.3","Tissue RNA - skeletal muscle [nTPM]":"7.6","Tissue RNA - skin 1 [nTPM]":"13.6","Tissue RNA - small intestine [nTPM]":"19.5","Tissue RNA - smooth muscle [nTPM]":"13.6","Tissue RNA - spinal cord [nTPM]":"8.1","Tissue RNA - spleen [nTPM]":"12.0","Tissue RNA - stomach 1 [nTPM]":"20.3","Tissue RNA - testis [nTPM]":"8.9","Tissue RNA - thalamus [nTPM]":"12.9","Tissue RNA - thymus [nTPM]":"17.2","Tissue RNA - thyroid gland [nTPM]":"10.8","Tissue RNA - tongue [nTPM]":"10.3","Tissue RNA - tonsil [nTPM]":"17.4","Tissue RNA - urinary bladder [nTPM]":"16.2","Tissue RNA - vagina [nTPM]":"11.4","Tissue RNA - white matter [nTPM]":"8.6","Cell RNA - A-431 [nTPM]":"15.9","Cell RNA - A549 [nTPM]":"14.3","Cell RNA - AF22 [nTPM]":"39.4","Cell RNA - AN3-CA [nTPM]":"20.7","Cell RNA - ASC diff [nTPM]":"14.1","Cell RNA - ASC TERT1 [nTPM]":"19.9","Cell RNA - BEWO [nTPM]":"68.9","Cell RNA - BJ [nTPM]":"17.3","Cell RNA - BJ hTERT+ [nTPM]":"22.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.9","Cell RNA - CACO-2 [nTPM]":"51.5","Cell RNA - CAPAN-2 [nTPM]":"30.7","Cell RNA - Daudi [nTPM]":"38.7","Cell RNA - EFO-21 [nTPM]":"10.4","Cell RNA - fHDF\/TERT166 [nTPM]":"32.0","Cell RNA - GAMG [nTPM]":"23.4","Cell RNA - HaCaT [nTPM]":"18.6","Cell RNA - HAP1 [nTPM]":"44.9","Cell RNA - HBEC3-KT [nTPM]":"17.3","Cell RNA - HBF TERT88 [nTPM]":"34.3","Cell RNA - HDLM-2 [nTPM]":"26.7","Cell RNA - HEK 293 [nTPM]":"15.0","Cell RNA - HEL [nTPM]":"37.6","Cell RNA - HeLa [nTPM]":"17.6","Cell RNA - Hep G2 [nTPM]":"15.6","Cell RNA - HHSteC [nTPM]":"15.8","Cell RNA - HL-60 [nTPM]":"32.8","Cell RNA - HMC-1 [nTPM]":"25.6","Cell RNA - HSkMC [nTPM]":"18.1","Cell RNA - hTCEpi [nTPM]":"25.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.9","Cell RNA - hTERT-HME1 [nTPM]":"20.2","Cell RNA - hTERT-RPE1 [nTPM]":"33.6","Cell RNA - HUVEC TERT2 [nTPM]":"27.1","Cell RNA - JURKAT [nTPM]":"28.7","Cell RNA - K-562 [nTPM]":"28.0","Cell RNA - Karpas-707 [nTPM]":"17.3","Cell RNA - LHCN-M2 [nTPM]":"27.6","Cell RNA - MCF7 [nTPM]":"14.1","Cell RNA - MOLT-4 [nTPM]":"46.8","Cell RNA - NB-4 [nTPM]":"56.6","Cell RNA - NTERA-2 [nTPM]":"87.6","Cell RNA - OE19 [nTPM]":"25.3","Cell RNA - PC-3 [nTPM]":"7.4","Cell RNA - REH [nTPM]":"43.4","Cell RNA - RH-30 [nTPM]":"39.9","Cell RNA - RPMI-8226 [nTPM]":"59.9","Cell RNA - RPTEC TERT1 [nTPM]":"27.2","Cell RNA - RT4 [nTPM]":"22.4","Cell RNA - SCLC-21H [nTPM]":"11.2","Cell RNA - SH-SY5Y [nTPM]":"32.4","Cell RNA - SiHa [nTPM]":"20.5","Cell RNA - SK-BR-3 [nTPM]":"24.9","Cell RNA - SK-MEL-30 [nTPM]":"21.8","Cell RNA - SuSa [nTPM]":"97.4","Cell RNA - T-47d [nTPM]":"28.9","Cell RNA - THP-1 [nTPM]":"26.9","Cell RNA - TIME [nTPM]":"28.1","Cell RNA - U-138 MG [nTPM]":"18.7","Cell RNA - U-2 OS [nTPM]":"24.8","Cell RNA - U-2197 [nTPM]":"38.2","Cell RNA - U-251 MG [nTPM]":"22.0","Cell RNA - U-266\/70 [nTPM]":"16.4","Cell RNA - U-266\/84 [nTPM]":"28.5","Cell RNA - U-698 [nTPM]":"41.9","Cell RNA - U-87 MG [nTPM]":"15.4","Cell RNA - U-937 [nTPM]":"20.0","Cell RNA - WM-115 [nTPM]":"15.0","Blood RNA - basophil [nTPM]":"31.2","Blood RNA - classical monocyte [nTPM]":"8.1","Blood RNA - eosinophil [nTPM]":"13.7","Blood RNA - gdT-cell [nTPM]":"11.6","Blood RNA - intermediate monocyte [nTPM]":"16.4","Blood RNA - MAIT T-cell [nTPM]":"7.9","Blood RNA - memory B-cell [nTPM]":"10.7","Blood RNA - memory CD4 T-cell [nTPM]":"10.1","Blood RNA - memory CD8 T-cell [nTPM]":"13.1","Blood RNA - myeloid DC [nTPM]":"7.9","Blood RNA - naive B-cell [nTPM]":"10.5","Blood RNA - naive CD4 T-cell [nTPM]":"13.8","Blood RNA - naive CD8 T-cell [nTPM]":"12.4","Blood RNA - neutrophil [nTPM]":"19.2","Blood RNA - NK-cell [nTPM]":"11.2","Blood RNA - non-classical monocyte [nTPM]":"22.4","Blood RNA - plasmacytoid DC [nTPM]":"7.8","Blood RNA - T-reg [nTPM]":"7.6","Blood RNA - total PBMC [nTPM]":"5.8","Brain RNA - amygdala [nTPM]":"11.0","Brain RNA - basal ganglia [nTPM]":"12.2","Brain RNA - cerebellum [nTPM]":"11.7","Brain RNA - cerebral cortex [nTPM]":"12.3","Brain RNA - hippocampal formation [nTPM]":"12.5","Brain RNA - hypothalamus [nTPM]":"12.0","Brain RNA - medulla oblongata [nTPM]":"8.5","Brain RNA - midbrain [nTPM]":"9.7","Brain RNA - pons [nTPM]":"8.7","Brain RNA - spinal cord [nTPM]":"8.1","Brain RNA - thalamus [nTPM]":"12.9","Brain RNA - white matter [nTPM]":"8.6","Single Cell Type RNA - Adipocytes [nTPM]":"73.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"32.1","Single Cell Type RNA - Astrocytes [nTPM]":"16.6","Single Cell Type RNA - B-cells [nTPM]":"90.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"100.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"96.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"57.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"72.3","Single Cell Type RNA - Bipolar cells [nTPM]":"63.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"59.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"38.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"64.3","Single Cell Type RNA - Club cells [nTPM]":"53.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"73.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"94.2","Single Cell Type RNA - dendritic cells [nTPM]":"66.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"161.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"58.7","Single Cell Type RNA - Ductal cells [nTPM]":"77.5","Single Cell Type RNA - Early spermatids [nTPM]":"3.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"45.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"40.8","Single Cell Type RNA - Endothelial cells [nTPM]":"77.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"78.8","Single Cell Type RNA - Erythroid cells [nTPM]":"60.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"42.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"91.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.4","Single Cell Type RNA - Fibroblasts [nTPM]":"50.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"98.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"53.4","Single Cell Type RNA - granulocytes [nTPM]":"24.1","Single Cell Type RNA - Granulosa cells [nTPM]":"26.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"77.8","Single Cell Type RNA - Hepatocytes [nTPM]":"56.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"51.5","Single Cell Type RNA - Horizontal cells [nTPM]":"92.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"45.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"92.9","Single Cell Type RNA - Ionocytes [nTPM]":"36.7","Single Cell Type RNA - Kupffer cells [nTPM]":"53.9","Single Cell Type RNA - Langerhans cells [nTPM]":"83.7","Single Cell Type RNA - Late spermatids [nTPM]":"5.9","Single Cell Type RNA - Leydig cells [nTPM]":"40.7","Single Cell Type RNA - Macrophages [nTPM]":"75.3","Single Cell Type RNA - Melanocytes [nTPM]":"62.2","Single Cell Type RNA - Microglial cells [nTPM]":"28.1","Single Cell Type RNA - monocytes [nTPM]":"82.9","Single Cell Type RNA - Muller glia cells [nTPM]":"41.7","Single Cell Type RNA - NK-cells [nTPM]":"49.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"114.2","Single Cell Type RNA - Paneth cells [nTPM]":"104.7","Single Cell Type RNA - Peritubular cells [nTPM]":"51.6","Single Cell Type RNA - Plasma cells [nTPM]":"85.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"130.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"63.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"52.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"42.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"65.8","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"53.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"52.2","Single Cell Type RNA - Spermatocytes [nTPM]":"53.0","Single Cell Type RNA - Spermatogonia [nTPM]":"40.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"93.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"155.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"139.1","Single Cell Type RNA - T-cells [nTPM]":"83.0","Single Cell Type RNA - Theca cells [nTPM]":"36.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"96.7","Single Cell Type RNA - Urothelial cells [nTPM]":"176.9"},{"Gene":"KYNU","Gene synonym":[],"Ensembl":"ENSG00000115919","Gene description":"Kynureninase","Uniprot":["Q16719"],"Chromosome":"2","Position":"142877657-143055833","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Pyridine nucleotide biosynthesis"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"88.4","urinary bladder":"51.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"136.1","Club cells":"109.6","Ionocytes":"114.0","Langerhans cells":"190.5","Macrophages":"122.9","monocytes":"248.0","Syncytiotrophoblasts":"104.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"17","RNA blood cell specific nTPM":{"classical monocyte":"109.4","intermediate monocyte":"142.7","memory B-cell":"73.6","myeloid DC":"111.2","naive B-cell":"51.3","non-classical monocyte":"123.4","plasmacytoid DC":"77.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"B-cells":"73.6","dendritic cells":"111.2","monocytes":"142.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"185.2","GAMG":"298.5","HeLa":"195.5","Hep G2":"128.3","hTEC\/SVTERT24-B":"106.5","U-87 MG":"314.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031686"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"590000","Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA031686":"AB_2673995"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.2","Tissue RNA - adrenal gland [nTPM]":"4.0","Tissue RNA - amygdala [nTPM]":"2.4","Tissue RNA - appendix [nTPM]":"24.4","Tissue RNA - basal ganglia [nTPM]":"2.1","Tissue RNA - bone marrow [nTPM]":"10.8","Tissue RNA - breast [nTPM]":"30.8","Tissue RNA - cerebellum [nTPM]":"2.7","Tissue RNA - cerebral cortex [nTPM]":"4.5","Tissue RNA - cervix [nTPM]":"4.0","Tissue RNA - choroid plexus [nTPM]":"3.6","Tissue RNA - colon [nTPM]":"2.4","Tissue RNA - duodenum [nTPM]":"1.1","Tissue RNA - endometrium 1 [nTPM]":"2.5","Tissue RNA - epididymis [nTPM]":"1.3","Tissue RNA - esophagus [nTPM]":"6.7","Tissue RNA - fallopian tube [nTPM]":"1.2","Tissue RNA - gallbladder [nTPM]":"9.8","Tissue RNA - heart muscle [nTPM]":"1.2","Tissue RNA - hippocampal formation [nTPM]":"2.0","Tissue RNA - hypothalamus [nTPM]":"1.6","Tissue RNA - kidney [nTPM]":"18.6","Tissue RNA - liver [nTPM]":"88.4","Tissue RNA - lung [nTPM]":"13.5","Tissue RNA - lymph node [nTPM]":"15.0","Tissue RNA - medulla oblongata [nTPM]":"2.8","Tissue RNA - midbrain [nTPM]":"1.7","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"0.9","Tissue RNA - parathyroid gland [nTPM]":"0.8","Tissue RNA - pituitary gland [nTPM]":"1.2","Tissue RNA - placenta [nTPM]":"7.3","Tissue RNA - pons [nTPM]":"3.3","Tissue RNA - prostate [nTPM]":"0.9","Tissue RNA - rectum [nTPM]":"2.9","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"1.8","Tissue RNA - seminal vesicle [nTPM]":"0.7","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"1.3","Tissue RNA - small intestine [nTPM]":"3.0","Tissue RNA - smooth muscle [nTPM]":"4.8","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"8.9","Tissue RNA - stomach 1 [nTPM]":"5.8","Tissue RNA - testis [nTPM]":"16.6","Tissue RNA - thalamus [nTPM]":"6.6","Tissue RNA - thymus [nTPM]":"3.9","Tissue RNA - thyroid gland [nTPM]":"2.3","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"28.9","Tissue RNA - urinary bladder [nTPM]":"51.5","Tissue RNA - vagina [nTPM]":"3.4","Tissue RNA - white matter [nTPM]":"2.1","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"185.2","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"0.4","Cell RNA - ASC TERT1 [nTPM]":"0.6","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"0.4","Cell RNA - BJ hTERT+ [nTPM]":"5.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"3.3","Cell RNA - CAPAN-2 [nTPM]":"2.7","Cell RNA - Daudi [nTPM]":"11.9","Cell RNA - EFO-21 [nTPM]":"0.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"298.5","Cell RNA - HaCaT [nTPM]":"0.7","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"0.6","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"4.3","Cell RNA - HeLa [nTPM]":"195.5","Cell RNA - Hep G2 [nTPM]":"128.3","Cell RNA - HHSteC [nTPM]":"2.4","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.8","Cell RNA - HSkMC [nTPM]":"17.3","Cell RNA - hTCEpi [nTPM]":"15.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"106.5","Cell RNA - hTERT-HME1 [nTPM]":"0.6","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"0.5","Cell RNA - Karpas-707 [nTPM]":"1.1","Cell RNA - LHCN-M2 [nTPM]":"1.7","Cell RNA - MCF7 [nTPM]":"96.7","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"11.8","Cell RNA - NTERA-2 [nTPM]":"0.7","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.9","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.9","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"3.2","Cell RNA - RT4 [nTPM]":"96.0","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"102.2","Cell RNA - SK-BR-3 [nTPM]":"15.2","Cell RNA - SK-MEL-30 [nTPM]":"1.0","Cell RNA - SuSa [nTPM]":"1.0","Cell RNA - T-47d [nTPM]":"50.9","Cell RNA - THP-1 [nTPM]":"26.5","Cell RNA - TIME [nTPM]":"1.5","Cell RNA - U-138 MG [nTPM]":"5.9","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"89.1","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"314.5","Cell RNA - U-937 [nTPM]":"22.2","Cell RNA - WM-115 [nTPM]":"0.6","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"109.4","Blood RNA - eosinophil [nTPM]":"2.4","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"142.7","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"73.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"111.2","Blood RNA - naive B-cell [nTPM]":"51.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"5.8","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"123.4","Blood RNA - plasmacytoid DC [nTPM]":"77.7","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"49.2","Brain RNA - amygdala [nTPM]":"2.4","Brain RNA - basal ganglia [nTPM]":"2.1","Brain RNA - cerebellum [nTPM]":"2.7","Brain RNA - cerebral cortex [nTPM]":"4.5","Brain RNA - hippocampal formation [nTPM]":"2.0","Brain RNA - hypothalamus [nTPM]":"1.6","Brain RNA - medulla oblongata [nTPM]":"2.8","Brain RNA - midbrain [nTPM]":"1.7","Brain RNA - pons [nTPM]":"3.3","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"6.6","Brain RNA - white matter [nTPM]":"2.1","Single Cell Type RNA - Adipocytes [nTPM]":"3.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"46.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"136.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"109.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.3","Single Cell Type RNA - dendritic cells [nTPM]":"16.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"14.5","Single Cell Type RNA - Early spermatids [nTPM]":"46.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.1","Single Cell Type RNA - Endothelial cells [nTPM]":"5.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.3","Single Cell Type RNA - Fibroblasts [nTPM]":"1.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"49.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"38.8","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"114.0","Single Cell Type RNA - Kupffer cells [nTPM]":"64.7","Single Cell Type RNA - Langerhans cells [nTPM]":"190.5","Single Cell Type RNA - Late spermatids [nTPM]":"42.8","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"122.9","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"29.0","Single Cell Type RNA - monocytes [nTPM]":"248.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"59.6","Single Cell Type RNA - Paneth cells [nTPM]":"1.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"5.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"44.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.9","Single Cell Type RNA - Spermatocytes [nTPM]":"47.8","Single Cell Type RNA - Spermatogonia [nTPM]":"8.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"104.7","Single Cell Type RNA - T-cells [nTPM]":"2.2","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.0","Single Cell Type RNA - Urothelial cells [nTPM]":"22.6"},{"Gene":"L2HGDH","Gene synonym":["C14orf160","FLJ12618"],"Ensembl":"ENSG00000087299","Gene description":"L-2-hydroxyglutarate dehydrogenase","Uniprot":["Q9H9P8"],"Chromosome":"14","Position":"50237563-50312229","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"56.3","Excitatory neurons":"60.5","Inhibitory neurons":"61.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"8.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065409","HPA069708"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA065409":"AB_2685485","HPA069708":"AB_2686179"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.75e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.6","Tissue RNA - adrenal gland [nTPM]":"2.5","Tissue RNA - amygdala [nTPM]":"2.9","Tissue RNA - appendix [nTPM]":"2.2","Tissue RNA - basal ganglia [nTPM]":"2.9","Tissue RNA - bone marrow [nTPM]":"2.7","Tissue RNA - breast [nTPM]":"3.7","Tissue RNA - cerebellum [nTPM]":"6.1","Tissue RNA - cerebral cortex [nTPM]":"5.5","Tissue RNA - cervix [nTPM]":"2.3","Tissue RNA - choroid plexus [nTPM]":"1.3","Tissue RNA - colon [nTPM]":"4.3","Tissue RNA - duodenum [nTPM]":"4.7","Tissue RNA - endometrium 1 [nTPM]":"2.4","Tissue RNA - epididymis [nTPM]":"3.0","Tissue RNA - esophagus [nTPM]":"5.1","Tissue RNA - fallopian tube [nTPM]":"3.1","Tissue RNA - gallbladder [nTPM]":"2.0","Tissue RNA - heart muscle [nTPM]":"5.2","Tissue RNA - hippocampal formation [nTPM]":"2.7","Tissue RNA - hypothalamus [nTPM]":"2.5","Tissue RNA - kidney [nTPM]":"19.6","Tissue RNA - liver [nTPM]":"12.6","Tissue RNA - lung [nTPM]":"1.8","Tissue RNA - lymph node [nTPM]":"2.6","Tissue RNA - medulla oblongata [nTPM]":"1.2","Tissue RNA - midbrain [nTPM]":"2.4","Tissue RNA - ovary [nTPM]":"2.5","Tissue RNA - pancreas [nTPM]":"3.9","Tissue RNA - parathyroid gland [nTPM]":"6.1","Tissue RNA - pituitary gland [nTPM]":"2.3","Tissue RNA - placenta [nTPM]":"1.7","Tissue RNA - pons [nTPM]":"1.1","Tissue RNA - prostate [nTPM]":"3.3","Tissue RNA - rectum [nTPM]":"5.0","Tissue RNA - retina [nTPM]":"11.4","Tissue RNA - salivary gland [nTPM]":"2.8","Tissue RNA - seminal vesicle [nTPM]":"3.2","Tissue RNA - skeletal muscle [nTPM]":"15.5","Tissue RNA - skin 1 [nTPM]":"5.1","Tissue RNA - small intestine [nTPM]":"3.6","Tissue RNA - smooth muscle [nTPM]":"2.5","Tissue RNA - spinal cord [nTPM]":"1.2","Tissue RNA - spleen [nTPM]":"1.3","Tissue RNA - stomach 1 [nTPM]":"4.3","Tissue RNA - testis [nTPM]":"3.9","Tissue RNA - thalamus [nTPM]":"2.4","Tissue RNA - thymus [nTPM]":"3.0","Tissue RNA - thyroid gland [nTPM]":"4.8","Tissue RNA - tongue [nTPM]":"14.7","Tissue RNA - tonsil [nTPM]":"3.4","Tissue RNA - urinary bladder [nTPM]":"2.4","Tissue RNA - vagina [nTPM]":"2.3","Tissue RNA - white matter [nTPM]":"4.1","Cell RNA - A-431 [nTPM]":"24.3","Cell RNA - A549 [nTPM]":"16.6","Cell RNA - AF22 [nTPM]":"6.8","Cell RNA - AN3-CA [nTPM]":"6.6","Cell RNA - ASC diff [nTPM]":"3.3","Cell RNA - ASC TERT1 [nTPM]":"2.2","Cell RNA - BEWO [nTPM]":"19.1","Cell RNA - BJ [nTPM]":"7.9","Cell RNA - BJ hTERT+ [nTPM]":"4.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.3","Cell RNA - CACO-2 [nTPM]":"26.8","Cell RNA - CAPAN-2 [nTPM]":"10.8","Cell RNA - Daudi [nTPM]":"19.0","Cell RNA - EFO-21 [nTPM]":"9.0","Cell RNA - fHDF\/TERT166 [nTPM]":"3.2","Cell RNA - GAMG [nTPM]":"9.7","Cell RNA - HaCaT [nTPM]":"17.4","Cell RNA - HAP1 [nTPM]":"20.6","Cell RNA - HBEC3-KT [nTPM]":"8.2","Cell RNA - HBF TERT88 [nTPM]":"13.5","Cell RNA - HDLM-2 [nTPM]":"15.2","Cell RNA - HEK 293 [nTPM]":"11.9","Cell RNA - HEL [nTPM]":"41.1","Cell RNA - HeLa [nTPM]":"10.9","Cell RNA - Hep G2 [nTPM]":"3.7","Cell RNA - HHSteC [nTPM]":"3.1","Cell RNA - HL-60 [nTPM]":"14.7","Cell RNA - HMC-1 [nTPM]":"13.7","Cell RNA - HSkMC [nTPM]":"2.0","Cell RNA - hTCEpi [nTPM]":"5.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.1","Cell RNA - hTERT-HME1 [nTPM]":"7.0","Cell RNA - hTERT-RPE1 [nTPM]":"3.1","Cell RNA - HUVEC TERT2 [nTPM]":"5.3","Cell RNA - JURKAT [nTPM]":"19.3","Cell RNA - K-562 [nTPM]":"14.7","Cell RNA - Karpas-707 [nTPM]":"11.6","Cell RNA - LHCN-M2 [nTPM]":"3.2","Cell RNA - MCF7 [nTPM]":"29.0","Cell RNA - MOLT-4 [nTPM]":"16.7","Cell RNA - NB-4 [nTPM]":"6.7","Cell RNA - NTERA-2 [nTPM]":"9.9","Cell RNA - OE19 [nTPM]":"20.6","Cell RNA - PC-3 [nTPM]":"17.6","Cell RNA - REH [nTPM]":"15.6","Cell RNA - RH-30 [nTPM]":"22.0","Cell RNA - RPMI-8226 [nTPM]":"14.8","Cell RNA - RPTEC TERT1 [nTPM]":"11.4","Cell RNA - RT4 [nTPM]":"28.0","Cell RNA - SCLC-21H [nTPM]":"13.8","Cell RNA - SH-SY5Y [nTPM]":"9.9","Cell RNA - SiHa [nTPM]":"23.3","Cell RNA - SK-BR-3 [nTPM]":"17.5","Cell RNA - SK-MEL-30 [nTPM]":"10.4","Cell RNA - SuSa [nTPM]":"9.0","Cell RNA - T-47d [nTPM]":"22.9","Cell RNA - THP-1 [nTPM]":"4.0","Cell RNA - TIME [nTPM]":"5.0","Cell RNA - U-138 MG [nTPM]":"7.7","Cell RNA - U-2 OS [nTPM]":"21.5","Cell RNA - U-2197 [nTPM]":"9.0","Cell RNA - U-251 MG [nTPM]":"10.6","Cell RNA - U-266\/70 [nTPM]":"10.5","Cell RNA - U-266\/84 [nTPM]":"25.6","Cell RNA - U-698 [nTPM]":"26.3","Cell RNA - U-87 MG [nTPM]":"4.3","Cell RNA - U-937 [nTPM]":"7.3","Cell RNA - WM-115 [nTPM]":"8.8","Blood RNA - basophil [nTPM]":"8.6","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.9","Blood RNA - gdT-cell [nTPM]":"0.9","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"2.2","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.0","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"1.7","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"1.7","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"1.6","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"2.9","Brain RNA - basal ganglia [nTPM]":"2.9","Brain RNA - cerebellum [nTPM]":"6.1","Brain RNA - cerebral cortex [nTPM]":"5.5","Brain RNA - hippocampal formation [nTPM]":"2.7","Brain RNA - hypothalamus [nTPM]":"2.5","Brain RNA - medulla oblongata [nTPM]":"1.2","Brain RNA - midbrain [nTPM]":"2.4","Brain RNA - pons [nTPM]":"1.1","Brain RNA - spinal cord [nTPM]":"1.2","Brain RNA - thalamus [nTPM]":"2.4","Brain RNA - white matter [nTPM]":"4.1","Single Cell Type RNA - Adipocytes [nTPM]":"1.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.2","Single Cell Type RNA - Astrocytes [nTPM]":"16.6","Single Cell Type RNA - B-cells [nTPM]":"5.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"15.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"20.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"56.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.4","Single Cell Type RNA - dendritic cells [nTPM]":"6.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"3.8","Single Cell Type RNA - Early spermatids [nTPM]":"35.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.8","Single Cell Type RNA - Endothelial cells [nTPM]":"4.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.8","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"60.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.6","Single Cell Type RNA - Fibroblasts [nTPM]":"5.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.6","Single Cell Type RNA - granulocytes [nTPM]":"18.9","Single Cell Type RNA - Granulosa cells [nTPM]":"6.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.9","Single Cell Type RNA - Hepatocytes [nTPM]":"14.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.1","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"61.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.7","Single Cell Type RNA - Langerhans cells [nTPM]":"0.6","Single Cell Type RNA - Late spermatids [nTPM]":"8.8","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"3.3","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"2.4","Single Cell Type RNA - Muller glia cells [nTPM]":"6.1","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.5","Single Cell Type RNA - Paneth cells [nTPM]":"3.6","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"3.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"21.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"40.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.9","Single Cell Type RNA - Spermatocytes [nTPM]":"14.3","Single Cell Type RNA - Spermatogonia [nTPM]":"12.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.9","Single Cell Type RNA - T-cells [nTPM]":"5.0","Single Cell Type RNA - Theca cells [nTPM]":"4.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.6","Single Cell Type RNA - Urothelial cells [nTPM]":"2.1"},{"Gene":"LACC1","Gene synonym":["C13orf31","FAMIN","FLJ38725"],"Ensembl":"ENSG00000179630","Gene description":"Laccase domain containing 1","Uniprot":["Q8IV20"],"Chromosome":"13","Position":"43879284-43893932","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Hydrolase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"27.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"39.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"3.0","eosinophil":"3.1","intermediate monocyte":"5.2","myeloid DC":"2.7","non-classical monocyte":"8.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"2.7","granulocytes":"3.1","monocytes":"8.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"37.1","TIME":"118.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034228","HPA040150","HPA044211"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB034228":"AB_1564163","HPA040150":"AB_10963540","HPA044211":"AB_10961258"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.4","Tissue RNA - adrenal gland [nTPM]":"6.6","Tissue RNA - amygdala [nTPM]":"12.7","Tissue RNA - appendix [nTPM]":"12.2","Tissue RNA - basal ganglia [nTPM]":"22.3","Tissue RNA - bone marrow [nTPM]":"1.9","Tissue RNA - breast [nTPM]":"5.4","Tissue RNA - cerebellum [nTPM]":"10.8","Tissue RNA - cerebral cortex [nTPM]":"20.6","Tissue RNA - cervix [nTPM]":"4.5","Tissue RNA - choroid plexus [nTPM]":"6.8","Tissue RNA - colon [nTPM]":"10.3","Tissue RNA - duodenum [nTPM]":"9.9","Tissue RNA - endometrium 1 [nTPM]":"3.9","Tissue RNA - epididymis [nTPM]":"3.2","Tissue RNA - esophagus [nTPM]":"6.8","Tissue RNA - fallopian tube [nTPM]":"3.2","Tissue RNA - gallbladder [nTPM]":"9.8","Tissue RNA - heart muscle [nTPM]":"10.1","Tissue RNA - hippocampal formation [nTPM]":"11.7","Tissue RNA - hypothalamus [nTPM]":"13.6","Tissue RNA - kidney [nTPM]":"4.8","Tissue RNA - liver [nTPM]":"7.2","Tissue RNA - lung [nTPM]":"6.4","Tissue RNA - lymph node [nTPM]":"8.8","Tissue RNA - medulla oblongata [nTPM]":"13.9","Tissue RNA - midbrain [nTPM]":"14.5","Tissue RNA - ovary [nTPM]":"3.4","Tissue RNA - pancreas [nTPM]":"3.5","Tissue RNA - parathyroid gland [nTPM]":"9.9","Tissue RNA - pituitary gland [nTPM]":"2.8","Tissue RNA - placenta [nTPM]":"6.1","Tissue RNA - pons [nTPM]":"15.2","Tissue RNA - prostate [nTPM]":"5.4","Tissue RNA - rectum [nTPM]":"13.3","Tissue RNA - retina [nTPM]":"0.8","Tissue RNA - salivary gland [nTPM]":"4.6","Tissue RNA - seminal vesicle [nTPM]":"4.9","Tissue RNA - skeletal muscle [nTPM]":"1.4","Tissue RNA - skin 1 [nTPM]":"4.8","Tissue RNA - small intestine [nTPM]":"13.8","Tissue RNA - smooth muscle [nTPM]":"5.8","Tissue RNA - spinal cord [nTPM]":"12.5","Tissue RNA - spleen [nTPM]":"7.2","Tissue RNA - stomach 1 [nTPM]":"6.8","Tissue RNA - testis [nTPM]":"9.4","Tissue RNA - thalamus [nTPM]":"17.3","Tissue RNA - thymus [nTPM]":"6.5","Tissue RNA - thyroid gland [nTPM]":"3.5","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"8.3","Tissue RNA - urinary bladder [nTPM]":"11.1","Tissue RNA - vagina [nTPM]":"2.9","Tissue RNA - white matter [nTPM]":"27.4","Cell RNA - A-431 [nTPM]":"4.7","Cell RNA - A549 [nTPM]":"2.5","Cell RNA - AF22 [nTPM]":"1.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"2.7","Cell RNA - ASC TERT1 [nTPM]":"12.3","Cell RNA - BEWO [nTPM]":"9.5","Cell RNA - BJ [nTPM]":"10.3","Cell RNA - BJ hTERT+ [nTPM]":"25.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.9","Cell RNA - CACO-2 [nTPM]":"5.3","Cell RNA - CAPAN-2 [nTPM]":"10.5","Cell RNA - Daudi [nTPM]":"9.9","Cell RNA - EFO-21 [nTPM]":"2.3","Cell RNA - fHDF\/TERT166 [nTPM]":"13.8","Cell RNA - GAMG [nTPM]":"6.0","Cell RNA - HaCaT [nTPM]":"6.7","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"2.9","Cell RNA - HBF TERT88 [nTPM]":"4.5","Cell RNA - HDLM-2 [nTPM]":"6.6","Cell RNA - HEK 293 [nTPM]":"1.7","Cell RNA - HEL [nTPM]":"12.3","Cell RNA - HeLa [nTPM]":"2.6","Cell RNA - Hep G2 [nTPM]":"1.9","Cell RNA - HHSteC [nTPM]":"12.5","Cell RNA - HL-60 [nTPM]":"2.9","Cell RNA - HMC-1 [nTPM]":"37.1","Cell RNA - HSkMC [nTPM]":"16.3","Cell RNA - hTCEpi [nTPM]":"8.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.3","Cell RNA - hTERT-HME1 [nTPM]":"12.6","Cell RNA - hTERT-RPE1 [nTPM]":"3.4","Cell RNA - HUVEC TERT2 [nTPM]":"5.9","Cell RNA - JURKAT [nTPM]":"1.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"7.1","Cell RNA - LHCN-M2 [nTPM]":"6.4","Cell RNA - MCF7 [nTPM]":"2.3","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"3.7","Cell RNA - NTERA-2 [nTPM]":"0.9","Cell RNA - OE19 [nTPM]":"2.6","Cell RNA - PC-3 [nTPM]":"2.2","Cell RNA - REH [nTPM]":"2.3","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"5.2","Cell RNA - RPTEC TERT1 [nTPM]":"7.4","Cell RNA - RT4 [nTPM]":"5.5","Cell RNA - SCLC-21H [nTPM]":"1.6","Cell RNA - SH-SY5Y [nTPM]":"2.5","Cell RNA - SiHa [nTPM]":"3.4","Cell RNA - SK-BR-3 [nTPM]":"1.2","Cell RNA - SK-MEL-30 [nTPM]":"4.9","Cell RNA - SuSa [nTPM]":"6.8","Cell RNA - T-47d [nTPM]":"1.5","Cell RNA - THP-1 [nTPM]":"6.2","Cell RNA - TIME [nTPM]":"118.2","Cell RNA - U-138 MG [nTPM]":"3.5","Cell RNA - U-2 OS [nTPM]":"1.1","Cell RNA - U-2197 [nTPM]":"18.8","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"2.4","Cell RNA - U-87 MG [nTPM]":"10.0","Cell RNA - U-937 [nTPM]":"3.7","Cell RNA - WM-115 [nTPM]":"8.0","Blood RNA - basophil [nTPM]":"1.0","Blood RNA - classical monocyte [nTPM]":"3.0","Blood RNA - eosinophil [nTPM]":"3.1","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"5.2","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"2.7","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"8.0","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"12.7","Brain RNA - basal ganglia [nTPM]":"22.3","Brain RNA - cerebellum [nTPM]":"10.8","Brain RNA - cerebral cortex [nTPM]":"20.6","Brain RNA - hippocampal formation [nTPM]":"11.7","Brain RNA - hypothalamus [nTPM]":"13.6","Brain RNA - medulla oblongata [nTPM]":"13.9","Brain RNA - midbrain [nTPM]":"14.5","Brain RNA - pons [nTPM]":"15.2","Brain RNA - spinal cord [nTPM]":"12.5","Brain RNA - thalamus [nTPM]":"17.3","Brain RNA - white matter [nTPM]":"27.4","Single Cell Type RNA - Adipocytes [nTPM]":"4.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.8","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"5.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"0.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"24.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"7.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.5","Single Cell Type RNA - dendritic cells [nTPM]":"1.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.5","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.4","Single Cell Type RNA - Endothelial cells [nTPM]":"7.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.3","Single Cell Type RNA - Fibroblasts [nTPM]":"4.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.5","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"9.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"5.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.4","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"17.6","Single Cell Type RNA - Langerhans cells [nTPM]":"10.3","Single Cell Type RNA - Late spermatids [nTPM]":"3.1","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"24.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"7.8","Single Cell Type RNA - Muller glia cells [nTPM]":"2.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"39.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.0","Single Cell Type RNA - Paneth cells [nTPM]":"11.2","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"0.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.0","Single Cell Type RNA - Spermatocytes [nTPM]":"17.1","Single Cell Type RNA - Spermatogonia [nTPM]":"16.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.2","Single Cell Type RNA - T-cells [nTPM]":"4.3","Single Cell Type RNA - Theca cells [nTPM]":"4.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.7","Single Cell Type RNA - Urothelial cells [nTPM]":"10.2"},{"Gene":"LAMP2","Gene synonym":["CD107b"],"Ensembl":"ENSG00000005893","Gene description":"Lysosomal associated membrane protein 2","Uniprot":["P13473"],"Chromosome":"X","Position":"120426148-120469365","Protein class":["CD markers","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Autophagy"],"Molecular function":null,"Disease involvement":["Disease variant","Glycogen storage disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"507.2","Syncytiotrophoblasts":"402.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"556.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"556.6"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005272","HPA029100"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"520000000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB005272":"AB_647855","HPA029100":"AB_10795022"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-3"},"Tissue RNA - adipose tissue [nTPM]":"54.2","Tissue RNA - adrenal gland [nTPM]":"68.7","Tissue RNA - amygdala [nTPM]":"80.3","Tissue RNA - appendix [nTPM]":"38.3","Tissue RNA - basal ganglia [nTPM]":"144.2","Tissue RNA - bone marrow [nTPM]":"62.8","Tissue RNA - breast [nTPM]":"56.3","Tissue RNA - cerebellum [nTPM]":"109.1","Tissue RNA - cerebral cortex [nTPM]":"135.5","Tissue RNA - cervix [nTPM]":"64.9","Tissue RNA - choroid plexus [nTPM]":"52.7","Tissue RNA - colon [nTPM]":"39.2","Tissue RNA - duodenum [nTPM]":"44.3","Tissue RNA - endometrium 1 [nTPM]":"44.3","Tissue RNA - epididymis [nTPM]":"55.1","Tissue RNA - esophagus [nTPM]":"79.4","Tissue RNA - fallopian tube [nTPM]":"44.1","Tissue RNA - gallbladder [nTPM]":"69.6","Tissue RNA - heart muscle [nTPM]":"45.3","Tissue RNA - hippocampal formation [nTPM]":"81.6","Tissue RNA - hypothalamus [nTPM]":"101.8","Tissue RNA - kidney [nTPM]":"85.5","Tissue RNA - liver [nTPM]":"129.9","Tissue RNA - lung [nTPM]":"54.2","Tissue RNA - lymph node [nTPM]":"34.1","Tissue RNA - medulla oblongata [nTPM]":"113.0","Tissue RNA - midbrain [nTPM]":"112.6","Tissue RNA - ovary [nTPM]":"49.1","Tissue RNA - pancreas [nTPM]":"57.8","Tissue RNA - parathyroid gland [nTPM]":"64.2","Tissue RNA - pituitary gland [nTPM]":"32.2","Tissue RNA - placenta [nTPM]":"47.9","Tissue RNA - pons [nTPM]":"120.6","Tissue RNA - prostate [nTPM]":"62.2","Tissue RNA - rectum [nTPM]":"35.0","Tissue RNA - retina [nTPM]":"32.6","Tissue RNA - salivary gland [nTPM]":"102.1","Tissue RNA - seminal vesicle [nTPM]":"55.1","Tissue RNA - skeletal muscle [nTPM]":"111.6","Tissue RNA - skin 1 [nTPM]":"67.2","Tissue RNA - small intestine [nTPM]":"42.4","Tissue RNA - smooth muscle [nTPM]":"42.8","Tissue RNA - spinal cord [nTPM]":"100.5","Tissue RNA - spleen [nTPM]":"39.5","Tissue RNA - stomach 1 [nTPM]":"51.8","Tissue RNA - testis [nTPM]":"26.2","Tissue RNA - thalamus [nTPM]":"100.9","Tissue RNA - thymus [nTPM]":"59.3","Tissue RNA - thyroid gland [nTPM]":"61.7","Tissue RNA - tongue [nTPM]":"67.4","Tissue RNA - tonsil [nTPM]":"36.6","Tissue RNA - urinary bladder [nTPM]":"43.4","Tissue RNA - vagina [nTPM]":"63.3","Tissue RNA - white matter [nTPM]":"211.7","Cell RNA - A-431 [nTPM]":"53.8","Cell RNA - A549 [nTPM]":"47.5","Cell RNA - AF22 [nTPM]":"40.1","Cell RNA - AN3-CA [nTPM]":"49.7","Cell RNA - ASC diff [nTPM]":"367.0","Cell RNA - ASC TERT1 [nTPM]":"140.9","Cell RNA - BEWO [nTPM]":"91.5","Cell RNA - BJ [nTPM]":"79.3","Cell RNA - BJ hTERT+ [nTPM]":"130.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"77.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"134.4","Cell RNA - CACO-2 [nTPM]":"42.7","Cell RNA - CAPAN-2 [nTPM]":"90.3","Cell RNA - Daudi [nTPM]":"47.9","Cell RNA - EFO-21 [nTPM]":"73.1","Cell RNA - fHDF\/TERT166 [nTPM]":"132.7","Cell RNA - GAMG [nTPM]":"236.2","Cell RNA - HaCaT [nTPM]":"84.9","Cell RNA - HAP1 [nTPM]":"56.7","Cell RNA - HBEC3-KT [nTPM]":"67.2","Cell RNA - HBF TERT88 [nTPM]":"125.5","Cell RNA - HDLM-2 [nTPM]":"43.6","Cell RNA - HEK 293 [nTPM]":"37.2","Cell RNA - HEL [nTPM]":"35.8","Cell RNA - HeLa [nTPM]":"46.4","Cell RNA - Hep G2 [nTPM]":"54.3","Cell RNA - HHSteC [nTPM]":"148.1","Cell RNA - HL-60 [nTPM]":"158.9","Cell RNA - HMC-1 [nTPM]":"73.2","Cell RNA - HSkMC [nTPM]":"151.5","Cell RNA - hTCEpi [nTPM]":"114.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"108.1","Cell RNA - hTERT-HME1 [nTPM]":"75.1","Cell RNA - hTERT-RPE1 [nTPM]":"188.6","Cell RNA - HUVEC TERT2 [nTPM]":"107.5","Cell RNA - JURKAT [nTPM]":"32.5","Cell RNA - K-562 [nTPM]":"42.1","Cell RNA - Karpas-707 [nTPM]":"122.9","Cell RNA - LHCN-M2 [nTPM]":"117.2","Cell RNA - MCF7 [nTPM]":"79.3","Cell RNA - MOLT-4 [nTPM]":"45.3","Cell RNA - NB-4 [nTPM]":"80.2","Cell RNA - NTERA-2 [nTPM]":"29.0","Cell RNA - OE19 [nTPM]":"63.7","Cell RNA - PC-3 [nTPM]":"42.6","Cell RNA - REH [nTPM]":"35.1","Cell RNA - RH-30 [nTPM]":"65.3","Cell RNA - RPMI-8226 [nTPM]":"73.1","Cell RNA - RPTEC TERT1 [nTPM]":"102.3","Cell RNA - RT4 [nTPM]":"36.9","Cell RNA - SCLC-21H [nTPM]":"14.0","Cell RNA - SH-SY5Y [nTPM]":"22.6","Cell RNA - SiHa [nTPM]":"99.7","Cell RNA - SK-BR-3 [nTPM]":"93.0","Cell RNA - SK-MEL-30 [nTPM]":"196.5","Cell RNA - SuSa [nTPM]":"57.4","Cell RNA - T-47d [nTPM]":"64.7","Cell RNA - THP-1 [nTPM]":"173.0","Cell RNA - TIME [nTPM]":"122.5","Cell RNA - U-138 MG [nTPM]":"114.1","Cell RNA - U-2 OS [nTPM]":"58.7","Cell RNA - U-2197 [nTPM]":"176.2","Cell RNA - U-251 MG [nTPM]":"261.5","Cell RNA - U-266\/70 [nTPM]":"68.5","Cell RNA - U-266\/84 [nTPM]":"78.6","Cell RNA - U-698 [nTPM]":"30.2","Cell RNA - U-87 MG [nTPM]":"131.4","Cell RNA - U-937 [nTPM]":"182.4","Cell RNA - WM-115 [nTPM]":"284.4","Blood RNA - basophil [nTPM]":"30.6","Blood RNA - classical monocyte [nTPM]":"114.9","Blood RNA - eosinophil [nTPM]":"224.1","Blood RNA - gdT-cell [nTPM]":"27.1","Blood RNA - intermediate monocyte [nTPM]":"97.1","Blood RNA - MAIT T-cell [nTPM]":"20.6","Blood RNA - memory B-cell [nTPM]":"17.1","Blood RNA - memory CD4 T-cell [nTPM]":"24.3","Blood RNA - memory CD8 T-cell [nTPM]":"24.5","Blood RNA - myeloid DC [nTPM]":"64.2","Blood RNA - naive B-cell [nTPM]":"22.5","Blood RNA - naive CD4 T-cell [nTPM]":"23.4","Blood RNA - naive CD8 T-cell [nTPM]":"21.8","Blood RNA - neutrophil [nTPM]":"556.6","Blood RNA - NK-cell [nTPM]":"31.8","Blood RNA - non-classical monocyte [nTPM]":"96.2","Blood RNA - plasmacytoid DC [nTPM]":"33.4","Blood RNA - T-reg [nTPM]":"33.4","Blood RNA - total PBMC [nTPM]":"66.3","Brain RNA - amygdala [nTPM]":"80.3","Brain RNA - basal ganglia [nTPM]":"144.2","Brain RNA - cerebellum [nTPM]":"109.1","Brain RNA - cerebral cortex [nTPM]":"135.5","Brain RNA - hippocampal formation [nTPM]":"81.6","Brain RNA - hypothalamus [nTPM]":"101.8","Brain RNA - medulla oblongata [nTPM]":"113.0","Brain RNA - midbrain [nTPM]":"112.6","Brain RNA - pons [nTPM]":"120.6","Brain RNA - spinal cord [nTPM]":"100.5","Brain RNA - thalamus [nTPM]":"100.9","Brain RNA - white matter [nTPM]":"211.7","Single Cell Type RNA - Adipocytes [nTPM]":"75.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"73.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"53.8","Single Cell Type RNA - Astrocytes [nTPM]":"52.2","Single Cell Type RNA - B-cells [nTPM]":"29.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"100.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"92.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"262.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"64.9","Single Cell Type RNA - Bipolar cells [nTPM]":"17.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"74.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"58.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"37.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"173.0","Single Cell Type RNA - Club cells [nTPM]":"155.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"66.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"163.7","Single Cell Type RNA - dendritic cells [nTPM]":"44.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"52.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"39.2","Single Cell Type RNA - Ductal cells [nTPM]":"217.7","Single Cell Type RNA - Early spermatids [nTPM]":"3.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"103.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"74.1","Single Cell Type RNA - Endothelial cells [nTPM]":"69.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"36.6","Single Cell Type RNA - Erythroid cells [nTPM]":"14.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"32.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"70.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"128.3","Single Cell Type RNA - Fibroblasts [nTPM]":"113.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"38.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"168.1","Single Cell Type RNA - granulocytes [nTPM]":"17.7","Single Cell Type RNA - Granulosa cells [nTPM]":"46.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"87.8","Single Cell Type RNA - Hepatocytes [nTPM]":"176.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"208.0","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"40.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"32.6","Single Cell Type RNA - Ionocytes [nTPM]":"134.3","Single Cell Type RNA - Kupffer cells [nTPM]":"133.1","Single Cell Type RNA - Langerhans cells [nTPM]":"80.4","Single Cell Type RNA - Late spermatids [nTPM]":"8.6","Single Cell Type RNA - Leydig cells [nTPM]":"113.7","Single Cell Type RNA - Macrophages [nTPM]":"135.5","Single Cell Type RNA - Melanocytes [nTPM]":"131.6","Single Cell Type RNA - Microglial cells [nTPM]":"33.7","Single Cell Type RNA - monocytes [nTPM]":"132.7","Single Cell Type RNA - Muller glia cells [nTPM]":"116.3","Single Cell Type RNA - NK-cells [nTPM]":"50.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"57.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"507.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"62.5","Single Cell Type RNA - Paneth cells [nTPM]":"54.4","Single Cell Type RNA - Peritubular cells [nTPM]":"109.9","Single Cell Type RNA - Plasma cells [nTPM]":"66.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"100.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"97.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"154.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"75.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.5","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"176.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"61.7","Single Cell Type RNA - Spermatocytes [nTPM]":"6.4","Single Cell Type RNA - Spermatogonia [nTPM]":"13.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"78.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"136.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"402.4","Single Cell Type RNA - T-cells [nTPM]":"34.5","Single Cell Type RNA - Theca cells [nTPM]":"71.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"34.8","Single Cell Type RNA - Urothelial cells [nTPM]":"92.9"},{"Gene":"LARS1","Gene synonym":["FLJ10595","FLJ21788","HSPC192","LARS","LEUS","RNTLS"],"Ensembl":"ENSG00000133706","Gene description":"Leucyl-tRNA synthetase 1","Uniprot":["Q9P2J5"],"Chromosome":"5","Position":"146110566-146182696","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"26.8","Cardiomyocytes":"135.7","Cytotrophoblasts":"39.2","Extravillous trophoblasts":"40.3","Hofbauer cells":"36.7","Smooth muscle cells":"22.7","Syncytiotrophoblasts":"33.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036424","HPA040881"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Nuclear bodies","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA036424":"AB_10670102","HPA040881":"AB_2677185"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.78e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.98e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Tissue RNA - adipose tissue [nTPM]":"35.4","Tissue RNA - adrenal gland [nTPM]":"37.0","Tissue RNA - amygdala [nTPM]":"40.0","Tissue RNA - appendix [nTPM]":"26.6","Tissue RNA - basal ganglia [nTPM]":"42.0","Tissue RNA - bone marrow [nTPM]":"20.2","Tissue RNA - breast [nTPM]":"46.3","Tissue RNA - cerebellum [nTPM]":"42.8","Tissue RNA - cerebral cortex [nTPM]":"48.9","Tissue RNA - cervix [nTPM]":"33.9","Tissue RNA - choroid plexus [nTPM]":"44.0","Tissue RNA - colon [nTPM]":"34.4","Tissue RNA - duodenum [nTPM]":"18.4","Tissue RNA - endometrium 1 [nTPM]":"33.9","Tissue RNA - epididymis [nTPM]":"35.4","Tissue RNA - esophagus [nTPM]":"35.0","Tissue RNA - fallopian tube [nTPM]":"34.8","Tissue RNA - gallbladder [nTPM]":"18.7","Tissue RNA - heart muscle [nTPM]":"38.5","Tissue RNA - hippocampal formation [nTPM]":"40.4","Tissue RNA - hypothalamus [nTPM]":"44.3","Tissue RNA - kidney [nTPM]":"34.6","Tissue RNA - liver [nTPM]":"25.6","Tissue RNA - lung [nTPM]":"26.4","Tissue RNA - lymph node [nTPM]":"29.7","Tissue RNA - medulla oblongata [nTPM]":"42.3","Tissue RNA - midbrain [nTPM]":"42.9","Tissue RNA - ovary [nTPM]":"37.2","Tissue RNA - pancreas [nTPM]":"49.7","Tissue RNA - parathyroid gland [nTPM]":"34.7","Tissue RNA - pituitary gland [nTPM]":"37.0","Tissue RNA - placenta [nTPM]":"22.2","Tissue RNA - pons [nTPM]":"41.8","Tissue RNA - prostate [nTPM]":"35.6","Tissue RNA - rectum [nTPM]":"34.8","Tissue RNA - retina [nTPM]":"34.7","Tissue RNA - salivary gland [nTPM]":"40.0","Tissue RNA - seminal vesicle [nTPM]":"28.3","Tissue RNA - skeletal muscle [nTPM]":"70.6","Tissue RNA - skin 1 [nTPM]":"31.7","Tissue RNA - small intestine [nTPM]":"28.1","Tissue RNA - smooth muscle [nTPM]":"33.4","Tissue RNA - spinal cord [nTPM]":"43.1","Tissue RNA - spleen [nTPM]":"35.7","Tissue RNA - stomach 1 [nTPM]":"29.8","Tissue RNA - testis [nTPM]":"23.9","Tissue RNA - thalamus [nTPM]":"43.2","Tissue RNA - thymus [nTPM]":"32.7","Tissue RNA - thyroid gland [nTPM]":"34.7","Tissue RNA - tongue [nTPM]":"58.8","Tissue RNA - tonsil [nTPM]":"34.8","Tissue RNA - urinary bladder [nTPM]":"35.6","Tissue RNA - vagina [nTPM]":"30.9","Tissue RNA - white matter [nTPM]":"46.2","Cell RNA - A-431 [nTPM]":"56.1","Cell RNA - A549 [nTPM]":"59.5","Cell RNA - AF22 [nTPM]":"65.9","Cell RNA - AN3-CA [nTPM]":"125.9","Cell RNA - ASC diff [nTPM]":"88.0","Cell RNA - ASC TERT1 [nTPM]":"95.7","Cell RNA - BEWO [nTPM]":"102.5","Cell RNA - BJ [nTPM]":"45.5","Cell RNA - BJ hTERT+ [nTPM]":"57.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"71.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"92.4","Cell RNA - CACO-2 [nTPM]":"66.1","Cell RNA - CAPAN-2 [nTPM]":"59.8","Cell RNA - Daudi [nTPM]":"67.8","Cell RNA - EFO-21 [nTPM]":"32.7","Cell RNA - fHDF\/TERT166 [nTPM]":"91.2","Cell RNA - GAMG [nTPM]":"72.6","Cell RNA - HaCaT [nTPM]":"52.9","Cell RNA - HAP1 [nTPM]":"107.2","Cell RNA - HBEC3-KT [nTPM]":"116.5","Cell RNA - HBF TERT88 [nTPM]":"106.4","Cell RNA - HDLM-2 [nTPM]":"45.2","Cell RNA - HEK 293 [nTPM]":"88.2","Cell RNA - HEL [nTPM]":"65.5","Cell RNA - HeLa [nTPM]":"76.0","Cell RNA - Hep G2 [nTPM]":"58.5","Cell RNA - HHSteC [nTPM]":"122.7","Cell RNA - HL-60 [nTPM]":"101.4","Cell RNA - HMC-1 [nTPM]":"51.9","Cell RNA - HSkMC [nTPM]":"83.7","Cell RNA - hTCEpi [nTPM]":"153.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"92.0","Cell RNA - hTERT-HME1 [nTPM]":"173.3","Cell RNA - hTERT-RPE1 [nTPM]":"73.2","Cell RNA - HUVEC TERT2 [nTPM]":"87.7","Cell RNA - JURKAT [nTPM]":"108.0","Cell RNA - K-562 [nTPM]":"67.4","Cell RNA - Karpas-707 [nTPM]":"121.3","Cell RNA - LHCN-M2 [nTPM]":"83.4","Cell RNA - MCF7 [nTPM]":"56.9","Cell RNA - MOLT-4 [nTPM]":"102.8","Cell RNA - NB-4 [nTPM]":"116.1","Cell RNA - NTERA-2 [nTPM]":"126.8","Cell RNA - OE19 [nTPM]":"63.8","Cell RNA - PC-3 [nTPM]":"86.8","Cell RNA - REH [nTPM]":"75.0","Cell RNA - RH-30 [nTPM]":"62.0","Cell RNA - RPMI-8226 [nTPM]":"101.9","Cell RNA - RPTEC TERT1 [nTPM]":"73.6","Cell RNA - RT4 [nTPM]":"44.1","Cell RNA - SCLC-21H [nTPM]":"77.7","Cell RNA - SH-SY5Y [nTPM]":"97.3","Cell RNA - SiHa [nTPM]":"50.2","Cell RNA - SK-BR-3 [nTPM]":"111.6","Cell RNA - SK-MEL-30 [nTPM]":"221.2","Cell RNA - SuSa [nTPM]":"76.6","Cell RNA - T-47d [nTPM]":"103.1","Cell RNA - THP-1 [nTPM]":"159.3","Cell RNA - TIME [nTPM]":"63.4","Cell RNA - U-138 MG [nTPM]":"61.2","Cell RNA - U-2 OS [nTPM]":"44.3","Cell RNA - U-2197 [nTPM]":"56.7","Cell RNA - U-251 MG [nTPM]":"89.4","Cell RNA - U-266\/70 [nTPM]":"79.3","Cell RNA - U-266\/84 [nTPM]":"82.3","Cell RNA - U-698 [nTPM]":"86.3","Cell RNA - U-87 MG [nTPM]":"89.8","Cell RNA - U-937 [nTPM]":"164.1","Cell RNA - WM-115 [nTPM]":"79.1","Blood RNA - basophil [nTPM]":"1.1","Blood RNA - classical monocyte [nTPM]":"11.8","Blood RNA - eosinophil [nTPM]":"5.4","Blood RNA - gdT-cell [nTPM]":"14.5","Blood RNA - intermediate monocyte [nTPM]":"19.2","Blood RNA - MAIT T-cell [nTPM]":"19.6","Blood RNA - memory B-cell [nTPM]":"18.9","Blood RNA - memory CD4 T-cell [nTPM]":"16.6","Blood RNA - memory CD8 T-cell [nTPM]":"14.9","Blood RNA - myeloid DC [nTPM]":"21.2","Blood RNA - naive B-cell [nTPM]":"15.5","Blood RNA - naive CD4 T-cell [nTPM]":"21.2","Blood RNA - naive CD8 T-cell [nTPM]":"21.9","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"19.2","Blood RNA - non-classical monocyte [nTPM]":"16.7","Blood RNA - plasmacytoid DC [nTPM]":"16.6","Blood RNA - T-reg [nTPM]":"19.6","Blood RNA - total PBMC [nTPM]":"14.9","Brain RNA - amygdala [nTPM]":"40.0","Brain RNA - basal ganglia [nTPM]":"42.0","Brain RNA - cerebellum [nTPM]":"42.8","Brain RNA - cerebral cortex [nTPM]":"48.9","Brain RNA - hippocampal formation [nTPM]":"40.4","Brain RNA - hypothalamus [nTPM]":"44.3","Brain RNA - medulla oblongata [nTPM]":"42.3","Brain RNA - midbrain [nTPM]":"42.9","Brain RNA - pons [nTPM]":"41.8","Brain RNA - spinal cord [nTPM]":"43.1","Brain RNA - thalamus [nTPM]":"43.2","Brain RNA - white matter [nTPM]":"46.2","Single Cell Type RNA - Adipocytes [nTPM]":"26.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"4.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"135.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"39.2","Single Cell Type RNA - dendritic cells [nTPM]":"13.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"8.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"40.3","Single Cell Type RNA - Fibroblasts [nTPM]":"16.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"36.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"3.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"6.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"33.0","Single Cell Type RNA - T-cells [nTPM]":"2.8","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"LARS2","Gene synonym":["KIAA0028","LEURS","MGC26121","mtLeuRS"],"Ensembl":"ENSG00000011376","Gene description":"Leucyl-tRNA synthetase 2, mitochondrial","Uniprot":["Q15031"],"Chromosome":"3","Position":"45388561-45554726","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Deafness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"28.7","Excitatory neurons":"35.4","Inhibitory neurons":"37.8","Oligodendrocyte precursor cells":"22.6","Oligodendrocytes":"25.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035951","HPA045450","HPA066085"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA035951":"AB_10672997","HPA045450":"AB_2679328","HPA066085":"AB_2685612"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.71e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.32e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.3","Tissue RNA - adrenal gland [nTPM]":"4.7","Tissue RNA - amygdala [nTPM]":"9.5","Tissue RNA - appendix [nTPM]":"3.4","Tissue RNA - basal ganglia [nTPM]":"10.3","Tissue RNA - bone marrow [nTPM]":"2.4","Tissue RNA - breast [nTPM]":"3.9","Tissue RNA - cerebellum [nTPM]":"10.1","Tissue RNA - cerebral cortex [nTPM]":"11.7","Tissue RNA - cervix [nTPM]":"3.7","Tissue RNA - choroid plexus [nTPM]":"9.2","Tissue RNA - colon [nTPM]":"6.9","Tissue RNA - duodenum [nTPM]":"3.9","Tissue RNA - endometrium 1 [nTPM]":"4.6","Tissue RNA - epididymis [nTPM]":"4.3","Tissue RNA - esophagus [nTPM]":"4.2","Tissue RNA - fallopian tube [nTPM]":"4.5","Tissue RNA - gallbladder [nTPM]":"3.0","Tissue RNA - heart muscle [nTPM]":"5.5","Tissue RNA - hippocampal formation [nTPM]":"9.3","Tissue RNA - hypothalamus [nTPM]":"10.5","Tissue RNA - kidney [nTPM]":"7.5","Tissue RNA - liver [nTPM]":"8.1","Tissue RNA - lung [nTPM]":"2.9","Tissue RNA - lymph node [nTPM]":"4.3","Tissue RNA - medulla oblongata [nTPM]":"9.5","Tissue RNA - midbrain [nTPM]":"10.2","Tissue RNA - ovary [nTPM]":"3.8","Tissue RNA - pancreas [nTPM]":"2.4","Tissue RNA - parathyroid gland [nTPM]":"12.3","Tissue RNA - pituitary gland [nTPM]":"3.7","Tissue RNA - placenta [nTPM]":"4.2","Tissue RNA - pons [nTPM]":"9.5","Tissue RNA - prostate [nTPM]":"4.3","Tissue RNA - rectum [nTPM]":"6.9","Tissue RNA - retina [nTPM]":"4.2","Tissue RNA - salivary gland [nTPM]":"3.6","Tissue RNA - seminal vesicle [nTPM]":"4.2","Tissue RNA - skeletal muscle [nTPM]":"6.2","Tissue RNA - skin 1 [nTPM]":"3.6","Tissue RNA - small intestine [nTPM]":"2.9","Tissue RNA - smooth muscle [nTPM]":"4.4","Tissue RNA - spinal cord [nTPM]":"9.2","Tissue RNA - spleen [nTPM]":"3.2","Tissue RNA - stomach 1 [nTPM]":"3.6","Tissue RNA - testis [nTPM]":"2.2","Tissue RNA - thalamus [nTPM]":"11.5","Tissue RNA - thymus [nTPM]":"6.9","Tissue RNA - thyroid gland [nTPM]":"4.5","Tissue RNA - tongue [nTPM]":"6.4","Tissue RNA - tonsil [nTPM]":"4.8","Tissue RNA - urinary bladder [nTPM]":"5.0","Tissue RNA - vagina [nTPM]":"3.7","Tissue RNA - white matter [nTPM]":"8.5","Cell RNA - A-431 [nTPM]":"6.3","Cell RNA - A549 [nTPM]":"11.2","Cell RNA - AF22 [nTPM]":"10.7","Cell RNA - AN3-CA [nTPM]":"9.3","Cell RNA - ASC diff [nTPM]":"11.8","Cell RNA - ASC TERT1 [nTPM]":"13.0","Cell RNA - BEWO [nTPM]":"11.1","Cell RNA - BJ [nTPM]":"11.6","Cell RNA - BJ hTERT+ [nTPM]":"15.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.2","Cell RNA - CACO-2 [nTPM]":"20.3","Cell RNA - CAPAN-2 [nTPM]":"8.8","Cell RNA - Daudi [nTPM]":"13.8","Cell RNA - EFO-21 [nTPM]":"8.9","Cell RNA - fHDF\/TERT166 [nTPM]":"18.0","Cell RNA - GAMG [nTPM]":"18.2","Cell RNA - HaCaT [nTPM]":"5.8","Cell RNA - HAP1 [nTPM]":"49.0","Cell RNA - HBEC3-KT [nTPM]":"30.4","Cell RNA - HBF TERT88 [nTPM]":"16.0","Cell RNA - HDLM-2 [nTPM]":"9.5","Cell RNA - HEK 293 [nTPM]":"12.7","Cell RNA - HEL [nTPM]":"12.9","Cell RNA - HeLa [nTPM]":"13.6","Cell RNA - Hep G2 [nTPM]":"18.4","Cell RNA - HHSteC [nTPM]":"12.1","Cell RNA - HL-60 [nTPM]":"20.9","Cell RNA - HMC-1 [nTPM]":"4.4","Cell RNA - HSkMC [nTPM]":"19.0","Cell RNA - hTCEpi [nTPM]":"16.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.0","Cell RNA - hTERT-HME1 [nTPM]":"12.5","Cell RNA - hTERT-RPE1 [nTPM]":"13.1","Cell RNA - HUVEC TERT2 [nTPM]":"14.9","Cell RNA - JURKAT [nTPM]":"19.5","Cell RNA - K-562 [nTPM]":"25.1","Cell RNA - Karpas-707 [nTPM]":"5.5","Cell RNA - LHCN-M2 [nTPM]":"19.0","Cell RNA - MCF7 [nTPM]":"9.7","Cell RNA - MOLT-4 [nTPM]":"21.1","Cell RNA - NB-4 [nTPM]":"11.6","Cell RNA - NTERA-2 [nTPM]":"28.4","Cell RNA - OE19 [nTPM]":"15.0","Cell RNA - PC-3 [nTPM]":"21.9","Cell RNA - REH [nTPM]":"8.9","Cell RNA - RH-30 [nTPM]":"9.8","Cell RNA - RPMI-8226 [nTPM]":"16.9","Cell RNA - RPTEC TERT1 [nTPM]":"23.6","Cell RNA - RT4 [nTPM]":"18.8","Cell RNA - SCLC-21H [nTPM]":"7.6","Cell RNA - SH-SY5Y [nTPM]":"9.7","Cell RNA - SiHa [nTPM]":"17.3","Cell RNA - SK-BR-3 [nTPM]":"7.9","Cell RNA - SK-MEL-30 [nTPM]":"11.8","Cell RNA - SuSa [nTPM]":"13.5","Cell RNA - T-47d [nTPM]":"14.6","Cell RNA - THP-1 [nTPM]":"14.7","Cell RNA - TIME [nTPM]":"9.1","Cell RNA - U-138 MG [nTPM]":"12.1","Cell RNA - U-2 OS [nTPM]":"8.3","Cell RNA - U-2197 [nTPM]":"8.5","Cell RNA - U-251 MG [nTPM]":"12.3","Cell RNA - U-266\/70 [nTPM]":"5.3","Cell RNA - U-266\/84 [nTPM]":"12.3","Cell RNA - U-698 [nTPM]":"15.4","Cell RNA - U-87 MG [nTPM]":"14.0","Cell RNA - U-937 [nTPM]":"16.9","Cell RNA - WM-115 [nTPM]":"9.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"1.2","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"1.5","Blood RNA - memory B-cell [nTPM]":"1.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.7","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"1.2","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"1.9","Blood RNA - non-classical monocyte [nTPM]":"0.8","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"9.5","Brain RNA - basal ganglia [nTPM]":"10.3","Brain RNA - cerebellum [nTPM]":"10.1","Brain RNA - cerebral cortex [nTPM]":"11.7","Brain RNA - hippocampal formation [nTPM]":"9.3","Brain RNA - hypothalamus [nTPM]":"10.5","Brain RNA - medulla oblongata [nTPM]":"9.5","Brain RNA - midbrain [nTPM]":"10.2","Brain RNA - pons [nTPM]":"9.5","Brain RNA - spinal cord [nTPM]":"9.2","Brain RNA - thalamus [nTPM]":"11.5","Brain RNA - white matter [nTPM]":"8.5","Single Cell Type RNA - Adipocytes [nTPM]":"3.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.0","Single Cell Type RNA - Astrocytes [nTPM]":"28.7","Single Cell Type RNA - B-cells [nTPM]":"4.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"5.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"1.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.0","Single Cell Type RNA - dendritic cells [nTPM]":"3.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.7","Single Cell Type RNA - Endothelial cells [nTPM]":"4.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"35.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.2","Single Cell Type RNA - Fibroblasts [nTPM]":"3.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.9","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"9.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"7.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.4","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.9","Single Cell Type RNA - Langerhans cells [nTPM]":"1.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"2.6","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"2.3","Single Cell Type RNA - Muller glia cells [nTPM]":"4.0","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"25.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.2","Single Cell Type RNA - Paneth cells [nTPM]":"7.0","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"5.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"2.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.9","Single Cell Type RNA - T-cells [nTPM]":"3.2","Single Cell Type RNA - Theca cells [nTPM]":"8.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.8","Single Cell Type RNA - Urothelial cells [nTPM]":"1.7"},{"Gene":"LBR","Gene synonym":["DHCR14B","TDRD18"],"Ensembl":"ENSG00000143815","Gene description":"Lamin B receptor","Uniprot":["Q14739"],"Chromosome":"1","Position":"225401502-225428925","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["DNA-binding","Oxidoreductase","Receptor"],"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"248.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062236"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA062236":"AB_2684721"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.30e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Tissue RNA - adipose tissue [nTPM]":"28.6","Tissue RNA - adrenal gland [nTPM]":"9.1","Tissue RNA - amygdala [nTPM]":"8.8","Tissue RNA - appendix [nTPM]":"53.2","Tissue RNA - basal ganglia [nTPM]":"9.7","Tissue RNA - bone marrow [nTPM]":"95.7","Tissue RNA - breast [nTPM]":"17.1","Tissue RNA - cerebellum [nTPM]":"9.3","Tissue RNA - cerebral cortex [nTPM]":"11.9","Tissue RNA - cervix [nTPM]":"27.3","Tissue RNA - choroid plexus [nTPM]":"9.2","Tissue RNA - colon [nTPM]":"61.4","Tissue RNA - duodenum [nTPM]":"40.7","Tissue RNA - endometrium 1 [nTPM]":"47.0","Tissue RNA - epididymis [nTPM]":"44.4","Tissue RNA - esophagus [nTPM]":"29.7","Tissue RNA - fallopian tube [nTPM]":"31.8","Tissue RNA - gallbladder [nTPM]":"21.7","Tissue RNA - heart muscle [nTPM]":"10.0","Tissue RNA - hippocampal formation [nTPM]":"8.5","Tissue RNA - hypothalamus [nTPM]":"10.1","Tissue RNA - kidney [nTPM]":"19.4","Tissue RNA - liver [nTPM]":"47.3","Tissue RNA - lung [nTPM]":"19.2","Tissue RNA - lymph node [nTPM]":"81.6","Tissue RNA - medulla oblongata [nTPM]":"12.0","Tissue RNA - midbrain [nTPM]":"9.8","Tissue RNA - ovary [nTPM]":"19.4","Tissue RNA - pancreas [nTPM]":"16.9","Tissue RNA - parathyroid gland [nTPM]":"5.6","Tissue RNA - pituitary gland [nTPM]":"6.5","Tissue RNA - placenta [nTPM]":"27.6","Tissue RNA - pons [nTPM]":"11.2","Tissue RNA - prostate [nTPM]":"23.8","Tissue RNA - rectum [nTPM]":"46.2","Tissue RNA - retina [nTPM]":"5.3","Tissue RNA - salivary gland [nTPM]":"11.1","Tissue RNA - seminal vesicle [nTPM]":"36.7","Tissue RNA - skeletal muscle [nTPM]":"9.8","Tissue RNA - skin 1 [nTPM]":"13.8","Tissue RNA - small intestine [nTPM]":"39.9","Tissue RNA - smooth muscle [nTPM]":"41.4","Tissue RNA - spinal cord [nTPM]":"10.2","Tissue RNA - spleen [nTPM]":"41.5","Tissue RNA - stomach 1 [nTPM]":"28.2","Tissue RNA - testis [nTPM]":"20.5","Tissue RNA - thalamus [nTPM]":"9.5","Tissue RNA - thymus [nTPM]":"105.5","Tissue RNA - thyroid gland [nTPM]":"11.8","Tissue RNA - tongue [nTPM]":"12.8","Tissue RNA - tonsil [nTPM]":"70.7","Tissue RNA - urinary bladder [nTPM]":"32.3","Tissue RNA - vagina [nTPM]":"23.0","Tissue RNA - white matter [nTPM]":"13.1","Cell RNA - A-431 [nTPM]":"122.2","Cell RNA - A549 [nTPM]":"42.0","Cell RNA - AF22 [nTPM]":"154.9","Cell RNA - AN3-CA [nTPM]":"69.3","Cell RNA - ASC diff [nTPM]":"64.8","Cell RNA - ASC TERT1 [nTPM]":"39.7","Cell RNA - BEWO [nTPM]":"77.3","Cell RNA - BJ [nTPM]":"31.2","Cell RNA - BJ hTERT+ [nTPM]":"39.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"65.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"69.0","Cell RNA - CACO-2 [nTPM]":"87.2","Cell RNA - CAPAN-2 [nTPM]":"207.2","Cell RNA - Daudi [nTPM]":"248.4","Cell RNA - EFO-21 [nTPM]":"66.6","Cell RNA - fHDF\/TERT166 [nTPM]":"32.8","Cell RNA - GAMG [nTPM]":"38.6","Cell RNA - HaCaT [nTPM]":"88.8","Cell RNA - HAP1 [nTPM]":"114.2","Cell RNA - HBEC3-KT [nTPM]":"32.9","Cell RNA - HBF TERT88 [nTPM]":"98.5","Cell RNA - HDLM-2 [nTPM]":"142.2","Cell RNA - HEK 293 [nTPM]":"107.1","Cell RNA - HEL [nTPM]":"61.4","Cell RNA - HeLa [nTPM]":"40.4","Cell RNA - Hep G2 [nTPM]":"81.5","Cell RNA - HHSteC [nTPM]":"39.9","Cell RNA - HL-60 [nTPM]":"274.7","Cell RNA - HMC-1 [nTPM]":"105.5","Cell RNA - HSkMC [nTPM]":"34.3","Cell RNA - hTCEpi [nTPM]":"21.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"58.9","Cell RNA - hTERT-HME1 [nTPM]":"52.0","Cell RNA - hTERT-RPE1 [nTPM]":"33.1","Cell RNA - HUVEC TERT2 [nTPM]":"82.9","Cell RNA - JURKAT [nTPM]":"117.4","Cell RNA - K-562 [nTPM]":"189.6","Cell RNA - Karpas-707 [nTPM]":"164.6","Cell RNA - LHCN-M2 [nTPM]":"44.4","Cell RNA - MCF7 [nTPM]":"16.3","Cell RNA - MOLT-4 [nTPM]":"254.9","Cell RNA - NB-4 [nTPM]":"156.6","Cell RNA - NTERA-2 [nTPM]":"140.6","Cell RNA - OE19 [nTPM]":"121.8","Cell RNA - PC-3 [nTPM]":"14.2","Cell RNA - REH [nTPM]":"164.9","Cell RNA - RH-30 [nTPM]":"141.4","Cell RNA - RPMI-8226 [nTPM]":"234.0","Cell RNA - RPTEC TERT1 [nTPM]":"75.6","Cell RNA - RT4 [nTPM]":"52.7","Cell RNA - SCLC-21H [nTPM]":"40.6","Cell RNA - SH-SY5Y [nTPM]":"53.4","Cell RNA - SiHa [nTPM]":"52.7","Cell RNA - SK-BR-3 [nTPM]":"39.6","Cell RNA - SK-MEL-30 [nTPM]":"26.6","Cell RNA - SuSa [nTPM]":"68.2","Cell RNA - T-47d [nTPM]":"53.3","Cell RNA - THP-1 [nTPM]":"181.0","Cell RNA - TIME [nTPM]":"50.5","Cell RNA - U-138 MG [nTPM]":"17.6","Cell RNA - U-2 OS [nTPM]":"91.7","Cell RNA - U-2197 [nTPM]":"49.3","Cell RNA - U-251 MG [nTPM]":"115.9","Cell RNA - U-266\/70 [nTPM]":"56.6","Cell RNA - U-266\/84 [nTPM]":"83.0","Cell RNA - U-698 [nTPM]":"274.5","Cell RNA - U-87 MG [nTPM]":"24.3","Cell RNA - U-937 [nTPM]":"120.5","Cell RNA - WM-115 [nTPM]":"61.2","Blood RNA - basophil [nTPM]":"83.6","Blood RNA - classical monocyte [nTPM]":"44.3","Blood RNA - eosinophil [nTPM]":"67.3","Blood RNA - gdT-cell [nTPM]":"43.6","Blood RNA - intermediate monocyte [nTPM]":"31.6","Blood RNA - MAIT T-cell [nTPM]":"50.9","Blood RNA - memory B-cell [nTPM]":"39.0","Blood RNA - memory CD4 T-cell [nTPM]":"43.5","Blood RNA - memory CD8 T-cell [nTPM]":"48.8","Blood RNA - myeloid DC [nTPM]":"38.4","Blood RNA - naive B-cell [nTPM]":"39.5","Blood RNA - naive CD4 T-cell [nTPM]":"42.4","Blood RNA - naive CD8 T-cell [nTPM]":"52.9","Blood RNA - neutrophil [nTPM]":"211.4","Blood RNA - NK-cell [nTPM]":"41.3","Blood RNA - non-classical monocyte [nTPM]":"25.2","Blood RNA - plasmacytoid DC [nTPM]":"21.5","Blood RNA - T-reg [nTPM]":"61.9","Blood RNA - total PBMC [nTPM]":"69.8","Brain RNA - amygdala [nTPM]":"8.8","Brain RNA - basal ganglia [nTPM]":"9.7","Brain RNA - cerebellum [nTPM]":"9.3","Brain RNA - cerebral cortex [nTPM]":"11.9","Brain RNA - hippocampal formation [nTPM]":"8.5","Brain RNA - hypothalamus [nTPM]":"10.1","Brain RNA - medulla oblongata [nTPM]":"12.0","Brain RNA - midbrain [nTPM]":"9.8","Brain RNA - pons [nTPM]":"11.2","Brain RNA - spinal cord [nTPM]":"10.2","Brain RNA - thalamus [nTPM]":"9.5","Brain RNA - white matter [nTPM]":"13.1","Single Cell Type RNA - Adipocytes [nTPM]":"98.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"36.4","Single Cell Type RNA - Astrocytes [nTPM]":"13.4","Single Cell Type RNA - B-cells [nTPM]":"86.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"27.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"33.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.6","Single Cell Type RNA - Bipolar cells [nTPM]":"4.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"48.6","Single Cell Type RNA - Club cells [nTPM]":"34.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"40.5","Single Cell Type RNA - dendritic cells [nTPM]":"98.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"33.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"23.6","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"31.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"31.0","Single Cell Type RNA - Endothelial cells [nTPM]":"53.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"27.0","Single Cell Type RNA - Erythroid cells [nTPM]":"248.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"23.9","Single Cell Type RNA - Fibroblasts [nTPM]":"29.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"29.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"53.9","Single Cell Type RNA - granulocytes [nTPM]":"10.1","Single Cell Type RNA - Granulosa cells [nTPM]":"24.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"48.5","Single Cell Type RNA - Hepatocytes [nTPM]":"73.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"44.4","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"43.0","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"88.5","Single Cell Type RNA - Langerhans cells [nTPM]":"18.1","Single Cell Type RNA - Late spermatids [nTPM]":"3.4","Single Cell Type RNA - Leydig cells [nTPM]":"33.8","Single Cell Type RNA - Macrophages [nTPM]":"71.7","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"56.0","Single Cell Type RNA - Muller glia cells [nTPM]":"11.6","Single Cell Type RNA - NK-cells [nTPM]":"82.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"37.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"34.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.6","Single Cell Type RNA - Paneth cells [nTPM]":"24.6","Single Cell Type RNA - Peritubular cells [nTPM]":"32.4","Single Cell Type RNA - Plasma cells [nTPM]":"74.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"32.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"19.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"26.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"26.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"46.6","Single Cell Type RNA - Spermatocytes [nTPM]":"21.0","Single Cell Type RNA - Spermatogonia [nTPM]":"26.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"68.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"35.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.1","Single Cell Type RNA - T-cells [nTPM]":"81.3","Single Cell Type RNA - Theca cells [nTPM]":"13.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"73.8","Single Cell Type RNA - Urothelial cells [nTPM]":"36.7"},{"Gene":"LCAT","Gene synonym":[],"Ensembl":"ENSG00000213398","Gene description":"Lecithin-cholesterol acyltransferase","Uniprot":["P04180"],"Chromosome":"16","Position":"67939750-67944131","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Steroid metabolism","Sterol metabolism"],"Molecular function":["Acyltransferase","Hydrolase","Transferase"],"Disease involvement":["Corneal dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"liver":"283.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Hepatocytes":"219.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"1.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"76.5","Hep G2":"62.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"29.2"},"Antibody":["HPA044767"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":6470000000,"Blood concentration - Conc. blood MS [pg\/L]":"6400000000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA044767":"AB_2756312"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.50e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.21e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.71e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-3"},"Tissue RNA - adipose tissue [nTPM]":"29.5","Tissue RNA - adrenal gland [nTPM]":"20.8","Tissue RNA - amygdala [nTPM]":"29.3","Tissue RNA - appendix [nTPM]":"8.3","Tissue RNA - basal ganglia [nTPM]":"29.8","Tissue RNA - bone marrow [nTPM]":"4.2","Tissue RNA - breast [nTPM]":"27.2","Tissue RNA - cerebellum [nTPM]":"56.7","Tissue RNA - cerebral cortex [nTPM]":"37.5","Tissue RNA - cervix [nTPM]":"41.4","Tissue RNA - choroid plexus [nTPM]":"37.8","Tissue RNA - colon [nTPM]":"30.6","Tissue RNA - duodenum [nTPM]":"5.0","Tissue RNA - endometrium 1 [nTPM]":"28.7","Tissue RNA - epididymis [nTPM]":"9.1","Tissue RNA - esophagus [nTPM]":"13.4","Tissue RNA - fallopian tube [nTPM]":"26.1","Tissue RNA - gallbladder [nTPM]":"11.5","Tissue RNA - heart muscle [nTPM]":"42.0","Tissue RNA - hippocampal formation [nTPM]":"28.5","Tissue RNA - hypothalamus [nTPM]":"32.3","Tissue RNA - kidney [nTPM]":"33.2","Tissue RNA - liver [nTPM]":"283.0","Tissue RNA - lung [nTPM]":"36.1","Tissue RNA - lymph node [nTPM]":"7.5","Tissue RNA - medulla oblongata [nTPM]":"41.9","Tissue RNA - midbrain [nTPM]":"32.7","Tissue RNA - ovary [nTPM]":"28.5","Tissue RNA - pancreas [nTPM]":"17.7","Tissue RNA - parathyroid gland [nTPM]":"8.0","Tissue RNA - pituitary gland [nTPM]":"17.5","Tissue RNA - placenta [nTPM]":"17.8","Tissue RNA - pons [nTPM]":"31.6","Tissue RNA - prostate [nTPM]":"40.0","Tissue RNA - rectum [nTPM]":"4.8","Tissue RNA - retina [nTPM]":"2.8","Tissue RNA - salivary gland [nTPM]":"16.9","Tissue RNA - seminal vesicle [nTPM]":"18.6","Tissue RNA - skeletal muscle [nTPM]":"13.2","Tissue RNA - skin 1 [nTPM]":"32.0","Tissue RNA - small intestine [nTPM]":"17.8","Tissue RNA - smooth muscle [nTPM]":"12.3","Tissue RNA - spinal cord [nTPM]":"31.9","Tissue RNA - spleen [nTPM]":"23.3","Tissue RNA - stomach 1 [nTPM]":"16.5","Tissue RNA - testis [nTPM]":"11.3","Tissue RNA - thalamus [nTPM]":"33.4","Tissue RNA - thymus [nTPM]":"9.4","Tissue RNA - thyroid gland [nTPM]":"43.2","Tissue RNA - tongue [nTPM]":"8.9","Tissue RNA - tonsil [nTPM]":"4.4","Tissue RNA - urinary bladder [nTPM]":"27.5","Tissue RNA - vagina [nTPM]":"27.3","Tissue RNA - white matter [nTPM]":"32.0","Cell RNA - A-431 [nTPM]":"5.7","Cell RNA - A549 [nTPM]":"9.0","Cell RNA - AF22 [nTPM]":"13.0","Cell RNA - AN3-CA [nTPM]":"14.8","Cell RNA - ASC diff [nTPM]":"11.1","Cell RNA - ASC TERT1 [nTPM]":"15.6","Cell RNA - BEWO [nTPM]":"76.5","Cell RNA - BJ [nTPM]":"21.9","Cell RNA - BJ hTERT+ [nTPM]":"9.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.2","Cell RNA - CACO-2 [nTPM]":"29.5","Cell RNA - CAPAN-2 [nTPM]":"6.8","Cell RNA - Daudi [nTPM]":"3.1","Cell RNA - EFO-21 [nTPM]":"4.0","Cell RNA - fHDF\/TERT166 [nTPM]":"31.9","Cell RNA - GAMG [nTPM]":"5.3","Cell RNA - HaCaT [nTPM]":"19.4","Cell RNA - HAP1 [nTPM]":"3.1","Cell RNA - HBEC3-KT [nTPM]":"30.0","Cell RNA - HBF TERT88 [nTPM]":"8.9","Cell RNA - HDLM-2 [nTPM]":"1.5","Cell RNA - HEK 293 [nTPM]":"7.9","Cell RNA - HEL [nTPM]":"3.9","Cell RNA - HeLa [nTPM]":"22.8","Cell RNA - Hep G2 [nTPM]":"62.9","Cell RNA - HHSteC [nTPM]":"15.2","Cell RNA - HL-60 [nTPM]":"0.7","Cell RNA - HMC-1 [nTPM]":"10.3","Cell RNA - HSkMC [nTPM]":"27.1","Cell RNA - hTCEpi [nTPM]":"27.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"30.0","Cell RNA - hTERT-HME1 [nTPM]":"10.4","Cell RNA - hTERT-RPE1 [nTPM]":"19.5","Cell RNA - HUVEC TERT2 [nTPM]":"10.8","Cell RNA - JURKAT [nTPM]":"8.7","Cell RNA - K-562 [nTPM]":"8.7","Cell RNA - Karpas-707 [nTPM]":"1.2","Cell RNA - LHCN-M2 [nTPM]":"10.5","Cell RNA - MCF7 [nTPM]":"9.1","Cell RNA - MOLT-4 [nTPM]":"3.7","Cell RNA - NB-4 [nTPM]":"9.5","Cell RNA - NTERA-2 [nTPM]":"8.6","Cell RNA - OE19 [nTPM]":"1.1","Cell RNA - PC-3 [nTPM]":"5.0","Cell RNA - REH [nTPM]":"4.0","Cell RNA - RH-30 [nTPM]":"14.1","Cell RNA - RPMI-8226 [nTPM]":"3.3","Cell RNA - RPTEC TERT1 [nTPM]":"4.1","Cell RNA - RT4 [nTPM]":"9.6","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"6.7","Cell RNA - SiHa [nTPM]":"33.1","Cell RNA - SK-BR-3 [nTPM]":"1.6","Cell RNA - SK-MEL-30 [nTPM]":"3.9","Cell RNA - SuSa [nTPM]":"26.5","Cell RNA - T-47d [nTPM]":"18.6","Cell RNA - THP-1 [nTPM]":"6.0","Cell RNA - TIME [nTPM]":"20.6","Cell RNA - U-138 MG [nTPM]":"18.5","Cell RNA - U-2 OS [nTPM]":"28.8","Cell RNA - U-2197 [nTPM]":"20.7","Cell RNA - U-251 MG [nTPM]":"8.1","Cell RNA - U-266\/70 [nTPM]":"17.7","Cell RNA - U-266\/84 [nTPM]":"5.2","Cell RNA - U-698 [nTPM]":"8.3","Cell RNA - U-87 MG [nTPM]":"8.9","Cell RNA - U-937 [nTPM]":"2.5","Cell RNA - WM-115 [nTPM]":"16.5","Blood RNA - basophil [nTPM]":"0.9","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"1.9","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"29.3","Brain RNA - basal ganglia [nTPM]":"29.8","Brain RNA - cerebellum [nTPM]":"56.7","Brain RNA - cerebral cortex [nTPM]":"37.5","Brain RNA - hippocampal formation [nTPM]":"28.5","Brain RNA - hypothalamus [nTPM]":"32.3","Brain RNA - medulla oblongata [nTPM]":"41.9","Brain RNA - midbrain [nTPM]":"32.7","Brain RNA - pons [nTPM]":"31.6","Brain RNA - spinal cord [nTPM]":"31.9","Brain RNA - thalamus [nTPM]":"33.4","Brain RNA - white matter [nTPM]":"32.0","Single Cell Type RNA - Adipocytes [nTPM]":"16.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"27.4","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"3.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.7","Single Cell Type RNA - dendritic cells [nTPM]":"1.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.0","Single Cell Type RNA - Endothelial cells [nTPM]":"8.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"14.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.4","Single Cell Type RNA - Fibroblasts [nTPM]":"7.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.6","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"5.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.8","Single Cell Type RNA - Hepatocytes [nTPM]":"219.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"6.6","Single Cell Type RNA - Langerhans cells [nTPM]":"3.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"8.7","Single Cell Type RNA - Macrophages [nTPM]":"2.4","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"3.0","Single Cell Type RNA - Muller glia cells [nTPM]":"7.7","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"8.6","Single Cell Type RNA - Plasma cells [nTPM]":"1.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.9","Single Cell Type RNA - Spermatogonia [nTPM]":"1.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.2","Single Cell Type RNA - T-cells [nTPM]":"1.6","Single Cell Type RNA - Theca cells [nTPM]":"4.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"1.7"},{"Gene":"LCT","Gene synonym":[],"Ensembl":"ENSG00000115850","Gene description":"Lactase","Uniprot":["P09848"],"Chromosome":"2","Position":"135787850-135837184","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase","Multifunctional enzyme"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"187","RNA tissue specific nTPM":{"intestine":"225.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"1.4","Breast myoepithelial cells":"3.3","Early spermatids":"1.3","Proximal enterocytes":"2.8","Undifferentiated cells":"1.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"JURKAT":"2.5","MOLT-4":"4.9","RPMI-8226":"9.7"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"15","RNA mouse brain regional specific nTPM":{"hippocampal formation":"15.7"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"225.5","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"136.3","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"1.2","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"1.3","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"2.5","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"4.9","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"1.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"9.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.7","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"LDHD","Gene synonym":[],"Ensembl":"ENSG00000166816","Gene description":"Lactate dehydrogenase D","Uniprot":["Q86WU2"],"Chromosome":"16","Position":"75111860-75116780","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"85.6","liver":"135.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"37.3","Distal enterocytes":"80.2","Distal tubular cells":"37.2","Hepatocytes":"88.6","Proximal tubular cells":"118.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"32.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"11.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"45","RNA blood lineage specific nTPM":{"granulocytes":"11.1","monocytes":"4.8"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"11.4","HMC-1":"14.4","T-47d":"29.1","U-266\/70":"11.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041766","HPA048639","HPA066148"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA041766":"AB_2677660","HPA048639":"AB_2680473","HPA066148":"AB_2685626"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.61e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.95e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Tissue RNA - adipose tissue [nTPM]":"24.9","Tissue RNA - adrenal gland [nTPM]":"14.4","Tissue RNA - amygdala [nTPM]":"17.7","Tissue RNA - appendix [nTPM]":"2.1","Tissue RNA - basal ganglia [nTPM]":"19.7","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"11.7","Tissue RNA - cerebellum [nTPM]":"20.5","Tissue RNA - cerebral cortex [nTPM]":"22.6","Tissue RNA - cervix [nTPM]":"5.4","Tissue RNA - choroid plexus [nTPM]":"34.1","Tissue RNA - colon [nTPM]":"27.2","Tissue RNA - duodenum [nTPM]":"8.8","Tissue RNA - endometrium 1 [nTPM]":"3.5","Tissue RNA - epididymis [nTPM]":"1.1","Tissue RNA - esophagus [nTPM]":"10.8","Tissue RNA - fallopian tube [nTPM]":"5.5","Tissue RNA - gallbladder [nTPM]":"3.0","Tissue RNA - heart muscle [nTPM]":"85.6","Tissue RNA - hippocampal formation [nTPM]":"16.1","Tissue RNA - hypothalamus [nTPM]":"18.9","Tissue RNA - kidney [nTPM]":"36.1","Tissue RNA - liver [nTPM]":"135.5","Tissue RNA - lung [nTPM]":"4.9","Tissue RNA - lymph node [nTPM]":"0.8","Tissue RNA - medulla oblongata [nTPM]":"20.8","Tissue RNA - midbrain [nTPM]":"20.2","Tissue RNA - ovary [nTPM]":"16.4","Tissue RNA - pancreas [nTPM]":"18.7","Tissue RNA - parathyroid gland [nTPM]":"17.0","Tissue RNA - pituitary gland [nTPM]":"11.8","Tissue RNA - placenta [nTPM]":"0.7","Tissue RNA - pons [nTPM]":"22.4","Tissue RNA - prostate [nTPM]":"8.1","Tissue RNA - rectum [nTPM]":"9.7","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"21.3","Tissue RNA - seminal vesicle [nTPM]":"3.2","Tissue RNA - skeletal muscle [nTPM]":"68.7","Tissue RNA - skin 1 [nTPM]":"5.8","Tissue RNA - small intestine [nTPM]":"5.7","Tissue RNA - smooth muscle [nTPM]":"1.2","Tissue RNA - spinal cord [nTPM]":"17.0","Tissue RNA - spleen [nTPM]":"1.1","Tissue RNA - stomach 1 [nTPM]":"23.1","Tissue RNA - testis [nTPM]":"1.7","Tissue RNA - thalamus [nTPM]":"19.3","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"10.6","Tissue RNA - tongue [nTPM]":"52.7","Tissue RNA - tonsil [nTPM]":"0.6","Tissue RNA - urinary bladder [nTPM]":"2.6","Tissue RNA - vagina [nTPM]":"3.7","Tissue RNA - white matter [nTPM]":"17.5","Cell RNA - A-431 [nTPM]":"0.7","Cell RNA - A549 [nTPM]":"2.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"1.6","Cell RNA - ASC TERT1 [nTPM]":"1.4","Cell RNA - BEWO [nTPM]":"6.1","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"2.8","Cell RNA - CAPAN-2 [nTPM]":"2.6","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"2.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.9","Cell RNA - GAMG [nTPM]":"1.0","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.8","Cell RNA - Hep G2 [nTPM]":"11.4","Cell RNA - HHSteC [nTPM]":"2.6","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"14.4","Cell RNA - HSkMC [nTPM]":"2.0","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"2.5","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"5.3","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"1.4","Cell RNA - OE19 [nTPM]":"2.7","Cell RNA - PC-3 [nTPM]":"1.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"7.8","Cell RNA - RPTEC TERT1 [nTPM]":"1.4","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"5.2","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"0.7","Cell RNA - T-47d [nTPM]":"29.1","Cell RNA - THP-1 [nTPM]":"3.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"11.5","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.9","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"11.1","Blood RNA - classical monocyte [nTPM]":"2.2","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"3.6","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"4.8","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"17.7","Brain RNA - basal ganglia [nTPM]":"19.7","Brain RNA - cerebellum [nTPM]":"20.5","Brain RNA - cerebral cortex [nTPM]":"22.6","Brain RNA - hippocampal formation [nTPM]":"16.1","Brain RNA - hypothalamus [nTPM]":"18.9","Brain RNA - medulla oblongata [nTPM]":"20.8","Brain RNA - midbrain [nTPM]":"20.2","Brain RNA - pons [nTPM]":"22.4","Brain RNA - spinal cord [nTPM]":"17.0","Brain RNA - thalamus [nTPM]":"19.3","Brain RNA - white matter [nTPM]":"17.5","Single Cell Type RNA - Adipocytes [nTPM]":"1.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.7","Single Cell Type RNA - Astrocytes [nTPM]":"7.8","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"37.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"2.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"80.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"37.2","Single Cell Type RNA - Ductal cells [nTPM]":"2.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"1.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.2","Single Cell Type RNA - Fibroblasts [nTPM]":"2.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.8","Single Cell Type RNA - granulocytes [nTPM]":"10.2","Single Cell Type RNA - Granulosa cells [nTPM]":"2.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.2","Single Cell Type RNA - Hepatocytes [nTPM]":"88.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.2","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"6.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"3.0","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"2.0","Single Cell Type RNA - Muller glia cells [nTPM]":"12.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.0","Single Cell Type RNA - Paneth cells [nTPM]":"28.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"118.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.1","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"1.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.7","Single Cell Type RNA - Urothelial cells [nTPM]":"1.5"},{"Gene":"LFNG","Gene synonym":["SCDO3"],"Ensembl":"ENSG00000106003","Gene description":"LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase","Uniprot":["Q8NES3"],"Chromosome":"7","Position":"2512529-2529177","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Developmental protein","Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"74.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"40.3","Enteroendocrine cells":"87.4","monocytes":"38.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"37.7","OE19":"46.4","RH-30":"46.0","U-2 OS":"49.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069130"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Golgi apparatus"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"880000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nuclear membrane"],"Antibody RRID":{"HPA069130":"AB_2686091"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.36e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Tissue RNA - adipose tissue [nTPM]":"16.7","Tissue RNA - adrenal gland [nTPM]":"6.5","Tissue RNA - amygdala [nTPM]":"23.3","Tissue RNA - appendix [nTPM]":"17.3","Tissue RNA - basal ganglia [nTPM]":"25.9","Tissue RNA - bone marrow [nTPM]":"9.8","Tissue RNA - breast [nTPM]":"13.7","Tissue RNA - cerebellum [nTPM]":"29.3","Tissue RNA - cerebral cortex [nTPM]":"22.4","Tissue RNA - cervix [nTPM]":"9.9","Tissue RNA - choroid plexus [nTPM]":"11.1","Tissue RNA - colon [nTPM]":"23.1","Tissue RNA - duodenum [nTPM]":"15.5","Tissue RNA - endometrium 1 [nTPM]":"9.4","Tissue RNA - epididymis [nTPM]":"2.2","Tissue RNA - esophagus [nTPM]":"11.4","Tissue RNA - fallopian tube [nTPM]":"6.1","Tissue RNA - gallbladder [nTPM]":"11.8","Tissue RNA - heart muscle [nTPM]":"13.1","Tissue RNA - hippocampal formation [nTPM]":"17.4","Tissue RNA - hypothalamus [nTPM]":"30.1","Tissue RNA - kidney [nTPM]":"9.0","Tissue RNA - liver [nTPM]":"2.5","Tissue RNA - lung [nTPM]":"14.4","Tissue RNA - lymph node [nTPM]":"18.6","Tissue RNA - medulla oblongata [nTPM]":"34.1","Tissue RNA - midbrain [nTPM]":"35.6","Tissue RNA - ovary [nTPM]":"1.8","Tissue RNA - pancreas [nTPM]":"74.4","Tissue RNA - parathyroid gland [nTPM]":"3.0","Tissue RNA - pituitary gland [nTPM]":"3.7","Tissue RNA - placenta [nTPM]":"6.5","Tissue RNA - pons [nTPM]":"24.8","Tissue RNA - prostate [nTPM]":"17.1","Tissue RNA - rectum [nTPM]":"12.0","Tissue RNA - retina [nTPM]":"3.0","Tissue RNA - salivary gland [nTPM]":"33.4","Tissue RNA - seminal vesicle [nTPM]":"4.6","Tissue RNA - skeletal muscle [nTPM]":"4.6","Tissue RNA - skin 1 [nTPM]":"58.2","Tissue RNA - small intestine [nTPM]":"17.2","Tissue RNA - smooth muscle [nTPM]":"5.8","Tissue RNA - spinal cord [nTPM]":"25.0","Tissue RNA - spleen [nTPM]":"20.9","Tissue RNA - stomach 1 [nTPM]":"37.8","Tissue RNA - testis [nTPM]":"4.2","Tissue RNA - thalamus [nTPM]":"38.1","Tissue RNA - thymus [nTPM]":"5.8","Tissue RNA - thyroid gland [nTPM]":"6.7","Tissue RNA - tongue [nTPM]":"3.6","Tissue RNA - tonsil [nTPM]":"10.8","Tissue RNA - urinary bladder [nTPM]":"12.2","Tissue RNA - vagina [nTPM]":"13.8","Tissue RNA - white matter [nTPM]":"23.6","Cell RNA - A-431 [nTPM]":"1.5","Cell RNA - A549 [nTPM]":"14.3","Cell RNA - AF22 [nTPM]":"18.4","Cell RNA - AN3-CA [nTPM]":"2.5","Cell RNA - ASC diff [nTPM]":"2.0","Cell RNA - ASC TERT1 [nTPM]":"1.7","Cell RNA - BEWO [nTPM]":"1.2","Cell RNA - BJ [nTPM]":"5.4","Cell RNA - BJ hTERT+ [nTPM]":"2.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.9","Cell RNA - CACO-2 [nTPM]":"6.0","Cell RNA - CAPAN-2 [nTPM]":"37.7","Cell RNA - Daudi [nTPM]":"1.1","Cell RNA - EFO-21 [nTPM]":"16.7","Cell RNA - fHDF\/TERT166 [nTPM]":"14.8","Cell RNA - GAMG [nTPM]":"8.1","Cell RNA - HaCaT [nTPM]":"27.1","Cell RNA - HAP1 [nTPM]":"2.9","Cell RNA - HBEC3-KT [nTPM]":"5.1","Cell RNA - HBF TERT88 [nTPM]":"2.3","Cell RNA - HDLM-2 [nTPM]":"8.6","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"4.3","Cell RNA - HeLa [nTPM]":"7.7","Cell RNA - Hep G2 [nTPM]":"3.2","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"6.2","Cell RNA - HMC-1 [nTPM]":"7.7","Cell RNA - HSkMC [nTPM]":"3.3","Cell RNA - hTCEpi [nTPM]":"12.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.8","Cell RNA - hTERT-HME1 [nTPM]":"0.8","Cell RNA - hTERT-RPE1 [nTPM]":"3.2","Cell RNA - HUVEC TERT2 [nTPM]":"1.9","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"3.6","Cell RNA - MCF7 [nTPM]":"34.5","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"8.7","Cell RNA - NTERA-2 [nTPM]":"22.4","Cell RNA - OE19 [nTPM]":"46.4","Cell RNA - PC-3 [nTPM]":"10.3","Cell RNA - REH [nTPM]":"1.8","Cell RNA - RH-30 [nTPM]":"46.0","Cell RNA - RPMI-8226 [nTPM]":"2.9","Cell RNA - RPTEC TERT1 [nTPM]":"1.8","Cell RNA - RT4 [nTPM]":"4.5","Cell RNA - SCLC-21H [nTPM]":"16.9","Cell RNA - SH-SY5Y [nTPM]":"4.2","Cell RNA - SiHa [nTPM]":"6.2","Cell RNA - SK-BR-3 [nTPM]":"1.4","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"4.7","Cell RNA - T-47d [nTPM]":"10.2","Cell RNA - THP-1 [nTPM]":"7.3","Cell RNA - TIME [nTPM]":"4.5","Cell RNA - U-138 MG [nTPM]":"10.5","Cell RNA - U-2 OS [nTPM]":"49.7","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"15.4","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"1.4","Cell RNA - U-87 MG [nTPM]":"11.8","Cell RNA - U-937 [nTPM]":"16.4","Cell RNA - WM-115 [nTPM]":"2.0","Blood RNA - basophil [nTPM]":"6.3","Blood RNA - classical monocyte [nTPM]":"5.3","Blood RNA - eosinophil [nTPM]":"12.7","Blood RNA - gdT-cell [nTPM]":"1.8","Blood RNA - intermediate monocyte [nTPM]":"6.9","Blood RNA - MAIT T-cell [nTPM]":"2.0","Blood RNA - memory B-cell [nTPM]":"1.1","Blood RNA - memory CD4 T-cell [nTPM]":"1.7","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"2.3","Blood RNA - naive B-cell [nTPM]":"2.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.8","Blood RNA - neutrophil [nTPM]":"2.8","Blood RNA - NK-cell [nTPM]":"1.3","Blood RNA - non-classical monocyte [nTPM]":"6.6","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"4.2","Blood RNA - total PBMC [nTPM]":"1.7","Brain RNA - amygdala [nTPM]":"23.3","Brain RNA - basal ganglia [nTPM]":"25.9","Brain RNA - cerebellum [nTPM]":"29.3","Brain RNA - cerebral cortex [nTPM]":"22.4","Brain RNA - hippocampal formation [nTPM]":"17.4","Brain RNA - hypothalamus [nTPM]":"30.1","Brain RNA - medulla oblongata [nTPM]":"34.1","Brain RNA - midbrain [nTPM]":"35.6","Brain RNA - pons [nTPM]":"24.8","Brain RNA - spinal cord [nTPM]":"25.0","Brain RNA - thalamus [nTPM]":"38.1","Brain RNA - white matter [nTPM]":"23.6","Single Cell Type RNA - Adipocytes [nTPM]":"23.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.0","Single Cell Type RNA - Astrocytes [nTPM]":"18.9","Single Cell Type RNA - B-cells [nTPM]":"15.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"8.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"2.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"40.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.5","Single Cell Type RNA - Endothelial cells [nTPM]":"16.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"87.4","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"5.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"30.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.2","Single Cell Type RNA - granulocytes [nTPM]":"17.7","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.9","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"34.5","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"30.4","Single Cell Type RNA - Langerhans cells [nTPM]":"13.8","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"30.6","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"38.2","Single Cell Type RNA - Muller glia cells [nTPM]":"31.3","Single Cell Type RNA - NK-cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.7","Single Cell Type RNA - Paneth cells [nTPM]":"3.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"12.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"3.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"15.9","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"LGR4","Gene synonym":["GPR48"],"Ensembl":"ENSG00000205213","Gene description":"Leucine rich repeat containing G protein-coupled receptor 4","Uniprot":["Q9BXB1"],"Chromosome":"11","Position":"27365961-27472790","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Biological rhythms","Differentiation","Immunity","Innate immunity","Spermatogenesis","Wnt signaling pathway"],"Molecular function":["Developmental protein","G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"204.4","Distal enterocytes":"123.3","Glandular and luminal cells":"137.7","Syncytiotrophoblasts":"128.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HAP1":"83.5","RPTEC TERT1":"100.4","U-2197":"82.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030267","HPA054350"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centriolar satellite"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Centriolar satellite"],"Subcellular additional location":null,"Antibody RRID":{"HPA030267":"AB_10610004","HPA054350":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.84e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.00e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Tissue RNA - adipose tissue [nTPM]":"16.4","Tissue RNA - adrenal gland [nTPM]":"16.8","Tissue RNA - amygdala [nTPM]":"10.2","Tissue RNA - appendix [nTPM]":"8.1","Tissue RNA - basal ganglia [nTPM]":"10.2","Tissue RNA - bone marrow [nTPM]":"2.4","Tissue RNA - breast [nTPM]":"16.1","Tissue RNA - cerebellum [nTPM]":"13.0","Tissue RNA - cerebral cortex [nTPM]":"9.2","Tissue RNA - cervix [nTPM]":"7.5","Tissue RNA - choroid plexus [nTPM]":"10.2","Tissue RNA - colon [nTPM]":"36.8","Tissue RNA - duodenum [nTPM]":"22.6","Tissue RNA - endometrium 1 [nTPM]":"10.2","Tissue RNA - epididymis [nTPM]":"13.3","Tissue RNA - esophagus [nTPM]":"13.7","Tissue RNA - fallopian tube [nTPM]":"10.2","Tissue RNA - gallbladder [nTPM]":"9.0","Tissue RNA - heart muscle [nTPM]":"19.4","Tissue RNA - hippocampal formation [nTPM]":"7.8","Tissue RNA - hypothalamus [nTPM]":"10.5","Tissue RNA - kidney [nTPM]":"51.5","Tissue RNA - liver [nTPM]":"55.7","Tissue RNA - lung [nTPM]":"3.2","Tissue RNA - lymph node [nTPM]":"1.5","Tissue RNA - medulla oblongata [nTPM]":"14.1","Tissue RNA - midbrain [nTPM]":"10.4","Tissue RNA - ovary [nTPM]":"22.9","Tissue RNA - pancreas [nTPM]":"59.7","Tissue RNA - parathyroid gland [nTPM]":"6.4","Tissue RNA - pituitary gland [nTPM]":"6.8","Tissue RNA - placenta [nTPM]":"34.4","Tissue RNA - pons [nTPM]":"12.8","Tissue RNA - prostate [nTPM]":"15.4","Tissue RNA - rectum [nTPM]":"36.8","Tissue RNA - retina [nTPM]":"44.4","Tissue RNA - salivary gland [nTPM]":"18.1","Tissue RNA - seminal vesicle [nTPM]":"16.1","Tissue RNA - skeletal muscle [nTPM]":"14.4","Tissue RNA - skin 1 [nTPM]":"18.3","Tissue RNA - small intestine [nTPM]":"24.7","Tissue RNA - smooth muscle [nTPM]":"13.2","Tissue RNA - spinal cord [nTPM]":"13.4","Tissue RNA - spleen [nTPM]":"11.7","Tissue RNA - stomach 1 [nTPM]":"31.0","Tissue RNA - testis [nTPM]":"13.9","Tissue RNA - thalamus [nTPM]":"10.1","Tissue RNA - thymus [nTPM]":"4.4","Tissue RNA - thyroid gland [nTPM]":"15.2","Tissue RNA - tongue [nTPM]":"8.2","Tissue RNA - tonsil [nTPM]":"3.0","Tissue RNA - urinary bladder [nTPM]":"10.1","Tissue RNA - vagina [nTPM]":"11.7","Tissue RNA - white matter [nTPM]":"18.0","Cell RNA - A-431 [nTPM]":"28.3","Cell RNA - A549 [nTPM]":"50.7","Cell RNA - AF22 [nTPM]":"49.5","Cell RNA - AN3-CA [nTPM]":"5.7","Cell RNA - ASC diff [nTPM]":"4.5","Cell RNA - ASC TERT1 [nTPM]":"3.1","Cell RNA - BEWO [nTPM]":"56.0","Cell RNA - BJ [nTPM]":"15.7","Cell RNA - BJ hTERT+ [nTPM]":"14.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.8","Cell RNA - CACO-2 [nTPM]":"7.6","Cell RNA - CAPAN-2 [nTPM]":"0.5","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"10.1","Cell RNA - fHDF\/TERT166 [nTPM]":"21.2","Cell RNA - GAMG [nTPM]":"23.2","Cell RNA - HaCaT [nTPM]":"45.8","Cell RNA - HAP1 [nTPM]":"83.5","Cell RNA - HBEC3-KT [nTPM]":"31.1","Cell RNA - HBF TERT88 [nTPM]":"23.5","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"37.0","Cell RNA - HEL [nTPM]":"15.3","Cell RNA - HeLa [nTPM]":"28.4","Cell RNA - Hep G2 [nTPM]":"36.1","Cell RNA - HHSteC [nTPM]":"1.4","Cell RNA - HL-60 [nTPM]":"1.6","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"4.1","Cell RNA - hTCEpi [nTPM]":"19.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.5","Cell RNA - hTERT-HME1 [nTPM]":"21.0","Cell RNA - hTERT-RPE1 [nTPM]":"57.0","Cell RNA - HUVEC TERT2 [nTPM]":"7.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"4.5","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"5.7","Cell RNA - MCF7 [nTPM]":"9.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"2.7","Cell RNA - NTERA-2 [nTPM]":"47.9","Cell RNA - OE19 [nTPM]":"76.3","Cell RNA - PC-3 [nTPM]":"20.4","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"33.8","Cell RNA - RPMI-8226 [nTPM]":"3.3","Cell RNA - RPTEC TERT1 [nTPM]":"100.4","Cell RNA - RT4 [nTPM]":"12.1","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"6.0","Cell RNA - SiHa [nTPM]":"7.7","Cell RNA - SK-BR-3 [nTPM]":"45.7","Cell RNA - SK-MEL-30 [nTPM]":"4.6","Cell RNA - SuSa [nTPM]":"37.6","Cell RNA - T-47d [nTPM]":"15.1","Cell RNA - THP-1 [nTPM]":"23.4","Cell RNA - TIME [nTPM]":"22.6","Cell RNA - U-138 MG [nTPM]":"10.2","Cell RNA - U-2 OS [nTPM]":"8.2","Cell RNA - U-2197 [nTPM]":"82.6","Cell RNA - U-251 MG [nTPM]":"14.6","Cell RNA - U-266\/70 [nTPM]":"18.9","Cell RNA - U-266\/84 [nTPM]":"15.2","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"17.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"6.4","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"10.2","Brain RNA - basal ganglia [nTPM]":"10.2","Brain RNA - cerebellum [nTPM]":"13.0","Brain RNA - cerebral cortex [nTPM]":"9.2","Brain RNA - hippocampal formation [nTPM]":"7.8","Brain RNA - hypothalamus [nTPM]":"10.5","Brain RNA - medulla oblongata [nTPM]":"14.1","Brain RNA - midbrain [nTPM]":"10.4","Brain RNA - pons [nTPM]":"12.8","Brain RNA - spinal cord [nTPM]":"13.4","Brain RNA - thalamus [nTPM]":"10.1","Brain RNA - white matter [nTPM]":"18.0","Single Cell Type RNA - Adipocytes [nTPM]":"1.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"204.4","Single Cell Type RNA - B-cells [nTPM]":"1.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"33.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"38.7","Single Cell Type RNA - Bipolar cells [nTPM]":"18.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"26.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"15.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"55.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"123.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"21.4","Single Cell Type RNA - Early spermatids [nTPM]":"7.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"75.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.5","Single Cell Type RNA - Endothelial cells [nTPM]":"3.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.8","Single Cell Type RNA - Erythroid cells [nTPM]":"3.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"35.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"50.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"29.2","Single Cell Type RNA - Fibroblasts [nTPM]":"14.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"43.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"137.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"78.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"60.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.1","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"51.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"47.1","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"5.3","Single Cell Type RNA - Langerhans cells [nTPM]":"5.7","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"1.6","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"2.1","Single Cell Type RNA - Muller glia cells [nTPM]":"109.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"36.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"62.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"31.4","Single Cell Type RNA - Paneth cells [nTPM]":"48.8","Single Cell Type RNA - Peritubular cells [nTPM]":"17.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"37.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.0","Single Cell Type RNA - Spermatocytes [nTPM]":"1.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"36.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"128.6","Single Cell Type RNA - T-cells [nTPM]":"1.8","Single Cell Type RNA - Theca cells [nTPM]":"6.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"55.5","Single Cell Type RNA - Urothelial cells [nTPM]":"19.7"},{"Gene":"LHFPL5","Gene synonym":["DFNB67","dJ510O8.8","MGC33835","Tmhs"],"Ensembl":"ENSG00000197753","Gene description":"LHFPL tetraspan subfamily member 5","Uniprot":["Q8TAF8"],"Chromosome":"6","Position":"35797206-35845397","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"18.8","epididymis":"12.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"13.5","Excitatory neurons":"8.0","Glandular and luminal cells":"2.8","Inhibitory neurons":"3.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"3.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029421","HPA055110"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA029421":null,"HPA055110":"AB_2682697"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.9","Tissue RNA - adrenal gland [nTPM]":"1.1","Tissue RNA - amygdala [nTPM]":"4.1","Tissue RNA - appendix [nTPM]":"2.7","Tissue RNA - basal ganglia [nTPM]":"4.6","Tissue RNA - bone marrow [nTPM]":"18.8","Tissue RNA - breast [nTPM]":"0.8","Tissue RNA - cerebellum [nTPM]":"4.8","Tissue RNA - cerebral cortex [nTPM]":"5.6","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"0.9","Tissue RNA - duodenum [nTPM]":"3.0","Tissue RNA - endometrium 1 [nTPM]":"1.5","Tissue RNA - epididymis [nTPM]":"12.4","Tissue RNA - esophagus [nTPM]":"1.3","Tissue RNA - fallopian tube [nTPM]":"0.6","Tissue RNA - gallbladder [nTPM]":"1.7","Tissue RNA - heart muscle [nTPM]":"0.7","Tissue RNA - hippocampal formation [nTPM]":"3.6","Tissue RNA - hypothalamus [nTPM]":"2.6","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"0.8","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"2.8","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"1.1","Tissue RNA - pancreas [nTPM]":"5.6","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"1.3","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"1.0","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"8.2","Tissue RNA - salivary gland [nTPM]":"2.4","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"1.4","Tissue RNA - skin 1 [nTPM]":"7.6","Tissue RNA - small intestine [nTPM]":"2.5","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"2.2","Tissue RNA - stomach 1 [nTPM]":"1.7","Tissue RNA - testis [nTPM]":"1.5","Tissue RNA - thalamus [nTPM]":"1.9","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"1.4","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.6","Tissue RNA - urinary bladder [nTPM]":"0.6","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"2.7","Cell RNA - A-431 [nTPM]":"2.3","Cell RNA - A549 [nTPM]":"1.5","Cell RNA - AF22 [nTPM]":"3.0","Cell RNA - AN3-CA [nTPM]":"3.1","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.6","Cell RNA - BEWO [nTPM]":"4.6","Cell RNA - BJ [nTPM]":"1.6","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"2.7","Cell RNA - CAPAN-2 [nTPM]":"2.0","Cell RNA - Daudi [nTPM]":"3.6","Cell RNA - EFO-21 [nTPM]":"1.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.6","Cell RNA - GAMG [nTPM]":"1.9","Cell RNA - HaCaT [nTPM]":"2.9","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.8","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"1.6","Cell RNA - HEK 293 [nTPM]":"2.6","Cell RNA - HEL [nTPM]":"3.2","Cell RNA - HeLa [nTPM]":"5.3","Cell RNA - Hep G2 [nTPM]":"4.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"3.4","Cell RNA - HMC-1 [nTPM]":"2.2","Cell RNA - HSkMC [nTPM]":"0.5","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.3","Cell RNA - hTERT-HME1 [nTPM]":"0.4","Cell RNA - hTERT-RPE1 [nTPM]":"2.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"3.6","Cell RNA - K-562 [nTPM]":"3.1","Cell RNA - Karpas-707 [nTPM]":"5.1","Cell RNA - LHCN-M2 [nTPM]":"0.9","Cell RNA - MCF7 [nTPM]":"1.9","Cell RNA - MOLT-4 [nTPM]":"2.5","Cell RNA - NB-4 [nTPM]":"6.2","Cell RNA - NTERA-2 [nTPM]":"2.6","Cell RNA - OE19 [nTPM]":"0.7","Cell RNA - PC-3 [nTPM]":"1.5","Cell RNA - REH [nTPM]":"2.2","Cell RNA - RH-30 [nTPM]":"1.1","Cell RNA - RPMI-8226 [nTPM]":"2.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.7","Cell RNA - RT4 [nTPM]":"5.6","Cell RNA - SCLC-21H [nTPM]":"3.4","Cell RNA - SH-SY5Y [nTPM]":"1.9","Cell RNA - SiHa [nTPM]":"1.6","Cell RNA - SK-BR-3 [nTPM]":"2.3","Cell RNA - SK-MEL-30 [nTPM]":"1.0","Cell RNA - SuSa [nTPM]":"2.9","Cell RNA - T-47d [nTPM]":"2.4","Cell RNA - THP-1 [nTPM]":"1.9","Cell RNA - TIME [nTPM]":"2.6","Cell RNA - U-138 MG [nTPM]":"3.1","Cell RNA - U-2 OS [nTPM]":"1.7","Cell RNA - U-2197 [nTPM]":"2.5","Cell RNA - U-251 MG [nTPM]":"2.4","Cell RNA - U-266\/70 [nTPM]":"3.2","Cell RNA - U-266\/84 [nTPM]":"3.0","Cell RNA - U-698 [nTPM]":"3.1","Cell RNA - U-87 MG [nTPM]":"1.1","Cell RNA - U-937 [nTPM]":"3.6","Cell RNA - WM-115 [nTPM]":"1.6","Blood RNA - basophil [nTPM]":"2.9","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.9","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"3.3","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"4.1","Brain RNA - basal ganglia [nTPM]":"4.6","Brain RNA - cerebellum [nTPM]":"4.8","Brain RNA - cerebral cortex [nTPM]":"5.6","Brain RNA - hippocampal formation [nTPM]":"3.6","Brain RNA - hypothalamus [nTPM]":"2.6","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"1.9","Brain RNA - white matter [nTPM]":"2.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"LHFPL6","Gene synonym":["LHFP","MGC22429"],"Ensembl":"ENSG00000183722","Gene description":"LHFPL tetraspan subfamily member 6","Uniprot":["Q9Y693"],"Chromosome":"13","Position":"39209116-39603528","Protein class":["Disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"195.2","Endometrial stromal cells":"78.1","Extravillous trophoblasts":"156.9","Fibroblasts":"113.0","Smooth muscle cells":"131.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"myeloid DC":"6.2","plasmacytoid DC":"2.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"15","RNA blood lineage specific nTPM":{"dendritic cells":"6.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"255.1","HSkMC":"186.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058975"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA058975":"AB_2683866"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.20e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.30e-4"},"Tissue RNA - adipose tissue [nTPM]":"143.2","Tissue RNA - adrenal gland [nTPM]":"55.1","Tissue RNA - amygdala [nTPM]":"46.3","Tissue RNA - appendix [nTPM]":"18.6","Tissue RNA - basal ganglia [nTPM]":"49.9","Tissue RNA - bone marrow [nTPM]":"1.1","Tissue RNA - breast [nTPM]":"128.7","Tissue RNA - cerebellum [nTPM]":"59.2","Tissue RNA - cerebral cortex [nTPM]":"45.2","Tissue RNA - cervix [nTPM]":"51.6","Tissue RNA - choroid plexus [nTPM]":"57.2","Tissue RNA - colon [nTPM]":"51.7","Tissue RNA - duodenum [nTPM]":"10.8","Tissue RNA - endometrium 1 [nTPM]":"78.8","Tissue RNA - epididymis [nTPM]":"47.5","Tissue RNA - esophagus [nTPM]":"37.0","Tissue RNA - fallopian tube [nTPM]":"88.9","Tissue RNA - gallbladder [nTPM]":"74.5","Tissue RNA - heart muscle [nTPM]":"99.7","Tissue RNA - hippocampal formation [nTPM]":"45.6","Tissue RNA - hypothalamus [nTPM]":"57.3","Tissue RNA - kidney [nTPM]":"31.9","Tissue RNA - liver [nTPM]":"14.2","Tissue RNA - lung [nTPM]":"82.6","Tissue RNA - lymph node [nTPM]":"39.1","Tissue RNA - medulla oblongata [nTPM]":"54.9","Tissue RNA - midbrain [nTPM]":"56.8","Tissue RNA - ovary [nTPM]":"49.6","Tissue RNA - pancreas [nTPM]":"17.2","Tissue RNA - parathyroid gland [nTPM]":"18.2","Tissue RNA - pituitary gland [nTPM]":"26.9","Tissue RNA - placenta [nTPM]":"134.6","Tissue RNA - pons [nTPM]":"51.4","Tissue RNA - prostate [nTPM]":"30.8","Tissue RNA - rectum [nTPM]":"16.7","Tissue RNA - retina [nTPM]":"11.9","Tissue RNA - salivary gland [nTPM]":"34.7","Tissue RNA - seminal vesicle [nTPM]":"36.9","Tissue RNA - skeletal muscle [nTPM]":"32.1","Tissue RNA - skin 1 [nTPM]":"37.9","Tissue RNA - small intestine [nTPM]":"29.0","Tissue RNA - smooth muscle [nTPM]":"68.9","Tissue RNA - spinal cord [nTPM]":"47.8","Tissue RNA - spleen [nTPM]":"30.4","Tissue RNA - stomach 1 [nTPM]":"27.9","Tissue RNA - testis [nTPM]":"20.4","Tissue RNA - thalamus [nTPM]":"64.3","Tissue RNA - thymus [nTPM]":"17.0","Tissue RNA - thyroid gland [nTPM]":"64.2","Tissue RNA - tongue [nTPM]":"89.2","Tissue RNA - tonsil [nTPM]":"17.6","Tissue RNA - urinary bladder [nTPM]":"49.1","Tissue RNA - vagina [nTPM]":"48.3","Tissue RNA - white matter [nTPM]":"44.3","Cell RNA - A-431 [nTPM]":"11.5","Cell RNA - A549 [nTPM]":"4.0","Cell RNA - AF22 [nTPM]":"118.3","Cell RNA - AN3-CA [nTPM]":"5.1","Cell RNA - ASC diff [nTPM]":"255.1","Cell RNA - ASC TERT1 [nTPM]":"115.1","Cell RNA - BEWO [nTPM]":"51.6","Cell RNA - BJ [nTPM]":"61.8","Cell RNA - BJ hTERT+ [nTPM]":"88.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"30.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.1","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"11.6","Cell RNA - Daudi [nTPM]":"17.5","Cell RNA - EFO-21 [nTPM]":"1.3","Cell RNA - fHDF\/TERT166 [nTPM]":"86.6","Cell RNA - GAMG [nTPM]":"40.0","Cell RNA - HaCaT [nTPM]":"17.3","Cell RNA - HAP1 [nTPM]":"15.0","Cell RNA - HBEC3-KT [nTPM]":"36.2","Cell RNA - HBF TERT88 [nTPM]":"25.3","Cell RNA - HDLM-2 [nTPM]":"16.9","Cell RNA - HEK 293 [nTPM]":"17.2","Cell RNA - HEL [nTPM]":"47.3","Cell RNA - HeLa [nTPM]":"3.7","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"26.7","Cell RNA - HL-60 [nTPM]":"0.8","Cell RNA - HMC-1 [nTPM]":"0.9","Cell RNA - HSkMC [nTPM]":"186.4","Cell RNA - hTCEpi [nTPM]":"4.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"27.7","Cell RNA - hTERT-HME1 [nTPM]":"45.7","Cell RNA - hTERT-RPE1 [nTPM]":"27.6","Cell RNA - HUVEC TERT2 [nTPM]":"29.1","Cell RNA - JURKAT [nTPM]":"1.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"59.9","Cell RNA - MCF7 [nTPM]":"9.9","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"14.5","Cell RNA - NTERA-2 [nTPM]":"8.8","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"15.8","Cell RNA - REH [nTPM]":"7.7","Cell RNA - RH-30 [nTPM]":"51.3","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"20.9","Cell RNA - RT4 [nTPM]":"15.0","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"3.8","Cell RNA - SiHa [nTPM]":"5.6","Cell RNA - SK-BR-3 [nTPM]":"7.2","Cell RNA - SK-MEL-30 [nTPM]":"16.8","Cell RNA - SuSa [nTPM]":"67.4","Cell RNA - T-47d [nTPM]":"6.7","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"54.3","Cell RNA - U-138 MG [nTPM]":"77.9","Cell RNA - U-2 OS [nTPM]":"11.7","Cell RNA - U-2197 [nTPM]":"24.4","Cell RNA - U-251 MG [nTPM]":"33.9","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"48.9","Cell RNA - U-87 MG [nTPM]":"32.4","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"57.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"6.2","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"2.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"46.3","Brain RNA - basal ganglia [nTPM]":"49.9","Brain RNA - cerebellum [nTPM]":"59.2","Brain RNA - cerebral cortex [nTPM]":"45.2","Brain RNA - hippocampal formation [nTPM]":"45.6","Brain RNA - hypothalamus [nTPM]":"57.3","Brain RNA - medulla oblongata [nTPM]":"54.9","Brain RNA - midbrain [nTPM]":"56.8","Brain RNA - pons [nTPM]":"51.4","Brain RNA - spinal cord [nTPM]":"47.8","Brain RNA - thalamus [nTPM]":"64.3","Brain RNA - white matter [nTPM]":"44.3","Single Cell Type RNA - Adipocytes [nTPM]":"195.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"28.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"9.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"78.1","Single Cell Type RNA - Endothelial cells [nTPM]":"32.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"156.9","Single Cell Type RNA - Fibroblasts [nTPM]":"113.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.8","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"22.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"3.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"131.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.2","Single Cell Type RNA - T-cells [nTPM]":"1.2","Single Cell Type RNA - Theca cells [nTPM]":"45.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"LIAS","Gene synonym":["LAS"],"Ensembl":"ENSG00000121897","Gene description":"Lipoic acid synthetase","Uniprot":["O43766"],"Chromosome":"4","Position":"39459004-39485109","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"86.0","Late spermatids":"100.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018842","HPA019076"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"HPA018842":"AB_1852864","HPA019076":"AB_1852866"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.11e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.4","Tissue RNA - adrenal gland [nTPM]":"7.5","Tissue RNA - amygdala [nTPM]":"5.9","Tissue RNA - appendix [nTPM]":"3.0","Tissue RNA - basal ganglia [nTPM]":"6.5","Tissue RNA - bone marrow [nTPM]":"6.6","Tissue RNA - breast [nTPM]":"5.7","Tissue RNA - cerebellum [nTPM]":"7.6","Tissue RNA - cerebral cortex [nTPM]":"9.8","Tissue RNA - cervix [nTPM]":"5.1","Tissue RNA - choroid plexus [nTPM]":"5.9","Tissue RNA - colon [nTPM]":"6.4","Tissue RNA - duodenum [nTPM]":"5.5","Tissue RNA - endometrium 1 [nTPM]":"4.6","Tissue RNA - epididymis [nTPM]":"5.3","Tissue RNA - esophagus [nTPM]":"6.7","Tissue RNA - fallopian tube [nTPM]":"6.1","Tissue RNA - gallbladder [nTPM]":"3.6","Tissue RNA - heart muscle [nTPM]":"11.1","Tissue RNA - hippocampal formation [nTPM]":"6.2","Tissue RNA - hypothalamus [nTPM]":"6.7","Tissue RNA - kidney [nTPM]":"8.7","Tissue RNA - liver [nTPM]":"8.6","Tissue RNA - lung [nTPM]":"2.9","Tissue RNA - lymph node [nTPM]":"5.1","Tissue RNA - medulla oblongata [nTPM]":"6.3","Tissue RNA - midbrain [nTPM]":"6.4","Tissue RNA - ovary [nTPM]":"10.0","Tissue RNA - pancreas [nTPM]":"6.8","Tissue RNA - parathyroid gland [nTPM]":"6.5","Tissue RNA - pituitary gland [nTPM]":"4.0","Tissue RNA - placenta [nTPM]":"3.3","Tissue RNA - pons [nTPM]":"6.8","Tissue RNA - prostate [nTPM]":"4.1","Tissue RNA - rectum [nTPM]":"6.4","Tissue RNA - retina [nTPM]":"5.4","Tissue RNA - salivary gland [nTPM]":"4.3","Tissue RNA - seminal vesicle [nTPM]":"3.1","Tissue RNA - skeletal muscle [nTPM]":"27.2","Tissue RNA - skin 1 [nTPM]":"5.7","Tissue RNA - small intestine [nTPM]":"5.2","Tissue RNA - smooth muscle [nTPM]":"5.2","Tissue RNA - spinal cord [nTPM]":"5.5","Tissue RNA - spleen [nTPM]":"3.6","Tissue RNA - stomach 1 [nTPM]":"6.3","Tissue RNA - testis [nTPM]":"9.8","Tissue RNA - thalamus [nTPM]":"6.2","Tissue RNA - thymus [nTPM]":"4.3","Tissue RNA - thyroid gland [nTPM]":"4.2","Tissue RNA - tongue [nTPM]":"21.0","Tissue RNA - tonsil [nTPM]":"4.2","Tissue RNA - urinary bladder [nTPM]":"5.8","Tissue RNA - vagina [nTPM]":"4.7","Tissue RNA - white matter [nTPM]":"8.3","Cell RNA - A-431 [nTPM]":"5.7","Cell RNA - A549 [nTPM]":"4.5","Cell RNA - AF22 [nTPM]":"5.4","Cell RNA - AN3-CA [nTPM]":"5.2","Cell RNA - ASC diff [nTPM]":"11.5","Cell RNA - ASC TERT1 [nTPM]":"11.4","Cell RNA - BEWO [nTPM]":"4.8","Cell RNA - BJ [nTPM]":"6.6","Cell RNA - BJ hTERT+ [nTPM]":"3.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.1","Cell RNA - CACO-2 [nTPM]":"6.8","Cell RNA - CAPAN-2 [nTPM]":"7.8","Cell RNA - Daudi [nTPM]":"20.8","Cell RNA - EFO-21 [nTPM]":"7.3","Cell RNA - fHDF\/TERT166 [nTPM]":"2.5","Cell RNA - GAMG [nTPM]":"15.2","Cell RNA - HaCaT [nTPM]":"4.9","Cell RNA - HAP1 [nTPM]":"15.9","Cell RNA - HBEC3-KT [nTPM]":"9.1","Cell RNA - HBF TERT88 [nTPM]":"8.0","Cell RNA - HDLM-2 [nTPM]":"2.4","Cell RNA - HEK 293 [nTPM]":"4.0","Cell RNA - HEL [nTPM]":"8.8","Cell RNA - HeLa [nTPM]":"2.3","Cell RNA - Hep G2 [nTPM]":"7.0","Cell RNA - HHSteC [nTPM]":"10.4","Cell RNA - HL-60 [nTPM]":"19.1","Cell RNA - HMC-1 [nTPM]":"5.5","Cell RNA - HSkMC [nTPM]":"10.8","Cell RNA - hTCEpi [nTPM]":"14.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.1","Cell RNA - hTERT-HME1 [nTPM]":"22.4","Cell RNA - hTERT-RPE1 [nTPM]":"13.4","Cell RNA - HUVEC TERT2 [nTPM]":"7.0","Cell RNA - JURKAT [nTPM]":"12.7","Cell RNA - K-562 [nTPM]":"21.1","Cell RNA - Karpas-707 [nTPM]":"5.2","Cell RNA - LHCN-M2 [nTPM]":"7.5","Cell RNA - MCF7 [nTPM]":"3.6","Cell RNA - MOLT-4 [nTPM]":"10.9","Cell RNA - NB-4 [nTPM]":"24.9","Cell RNA - NTERA-2 [nTPM]":"7.3","Cell RNA - OE19 [nTPM]":"15.3","Cell RNA - PC-3 [nTPM]":"14.2","Cell RNA - REH [nTPM]":"9.1","Cell RNA - RH-30 [nTPM]":"15.2","Cell RNA - RPMI-8226 [nTPM]":"12.9","Cell RNA - RPTEC TERT1 [nTPM]":"7.1","Cell RNA - RT4 [nTPM]":"2.9","Cell RNA - SCLC-21H [nTPM]":"6.0","Cell RNA - SH-SY5Y [nTPM]":"4.8","Cell RNA - SiHa [nTPM]":"3.8","Cell RNA - SK-BR-3 [nTPM]":"4.9","Cell RNA - SK-MEL-30 [nTPM]":"22.5","Cell RNA - SuSa [nTPM]":"7.6","Cell RNA - T-47d [nTPM]":"5.6","Cell RNA - THP-1 [nTPM]":"8.8","Cell RNA - TIME [nTPM]":"2.6","Cell RNA - U-138 MG [nTPM]":"4.7","Cell RNA - U-2 OS [nTPM]":"10.6","Cell RNA - U-2197 [nTPM]":"6.3","Cell RNA - U-251 MG [nTPM]":"15.5","Cell RNA - U-266\/70 [nTPM]":"9.9","Cell RNA - U-266\/84 [nTPM]":"15.8","Cell RNA - U-698 [nTPM]":"14.3","Cell RNA - U-87 MG [nTPM]":"7.2","Cell RNA - U-937 [nTPM]":"22.2","Cell RNA - WM-115 [nTPM]":"4.0","Blood RNA - basophil [nTPM]":"2.5","Blood RNA - classical monocyte [nTPM]":"6.4","Blood RNA - eosinophil [nTPM]":"3.9","Blood RNA - gdT-cell [nTPM]":"5.7","Blood RNA - intermediate monocyte [nTPM]":"7.6","Blood RNA - MAIT T-cell [nTPM]":"12.7","Blood RNA - memory B-cell [nTPM]":"10.0","Blood RNA - memory CD4 T-cell [nTPM]":"8.1","Blood RNA - memory CD8 T-cell [nTPM]":"8.0","Blood RNA - myeloid DC [nTPM]":"6.2","Blood RNA - naive B-cell [nTPM]":"7.6","Blood RNA - naive CD4 T-cell [nTPM]":"16.2","Blood RNA - naive CD8 T-cell [nTPM]":"11.6","Blood RNA - neutrophil [nTPM]":"3.4","Blood RNA - NK-cell [nTPM]":"7.7","Blood RNA - non-classical monocyte [nTPM]":"5.6","Blood RNA - plasmacytoid DC [nTPM]":"5.5","Blood RNA - T-reg [nTPM]":"5.7","Blood RNA - total PBMC [nTPM]":"4.7","Brain RNA - amygdala [nTPM]":"5.9","Brain RNA - basal ganglia [nTPM]":"6.5","Brain RNA - cerebellum [nTPM]":"7.6","Brain RNA - cerebral cortex [nTPM]":"9.8","Brain RNA - hippocampal formation [nTPM]":"6.2","Brain RNA - hypothalamus [nTPM]":"6.7","Brain RNA - medulla oblongata [nTPM]":"6.3","Brain RNA - midbrain [nTPM]":"6.4","Brain RNA - pons [nTPM]":"6.8","Brain RNA - spinal cord [nTPM]":"5.5","Brain RNA - thalamus [nTPM]":"6.2","Brain RNA - white matter [nTPM]":"8.3","Single Cell Type RNA - Adipocytes [nTPM]":"11.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.6","Single Cell Type RNA - Astrocytes [nTPM]":"14.0","Single Cell Type RNA - B-cells [nTPM]":"12.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.0","Single Cell Type RNA - Bipolar cells [nTPM]":"25.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"20.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"12.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"24.0","Single Cell Type RNA - dendritic cells [nTPM]":"22.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"13.2","Single Cell Type RNA - Early spermatids [nTPM]":"86.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.8","Single Cell Type RNA - Endothelial cells [nTPM]":"10.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.1","Single Cell Type RNA - Erythroid cells [nTPM]":"12.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.2","Single Cell Type RNA - Fibroblasts [nTPM]":"10.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.3","Single Cell Type RNA - granulocytes [nTPM]":"17.7","Single Cell Type RNA - Granulosa cells [nTPM]":"19.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.4","Single Cell Type RNA - Hepatocytes [nTPM]":"19.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.5","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.5","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"13.5","Single Cell Type RNA - Langerhans cells [nTPM]":"7.8","Single Cell Type RNA - Late spermatids [nTPM]":"100.1","Single Cell Type RNA - Leydig cells [nTPM]":"10.2","Single Cell Type RNA - Macrophages [nTPM]":"11.4","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"17.6","Single Cell Type RNA - Muller glia cells [nTPM]":"15.4","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"22.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.3","Single Cell Type RNA - Paneth cells [nTPM]":"10.1","Single Cell Type RNA - Peritubular cells [nTPM]":"12.4","Single Cell Type RNA - Plasma cells [nTPM]":"5.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"32.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"26.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.5","Single Cell Type RNA - Spermatocytes [nTPM]":"64.9","Single Cell Type RNA - Spermatogonia [nTPM]":"25.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.6","Single Cell Type RNA - T-cells [nTPM]":"14.2","Single Cell Type RNA - Theca cells [nTPM]":"19.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.4","Single Cell Type RNA - Urothelial cells [nTPM]":"8.8"},{"Gene":"LIG4","Gene synonym":[],"Ensembl":"ENSG00000174405","Gene description":"DNA ligase 4","Uniprot":["P49917"],"Chromosome":"13","Position":"108207439-108218368","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","DNA damage","DNA recombination","DNA repair","DNA replication"],"Molecular function":["Ligase"],"Disease involvement":["Cancer-related genes","Disease variant","SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001334","HPA057325"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytoplasmic bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytoplasmic bodies"],"Antibody RRID":{"HPA001334":"AB_1078689","HPA057325":"AB_2732608"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-3"},"Tissue RNA - adipose tissue [nTPM]":"7.2","Tissue RNA - adrenal gland [nTPM]":"8.3","Tissue RNA - amygdala [nTPM]":"6.3","Tissue RNA - appendix [nTPM]":"8.6","Tissue RNA - basal ganglia [nTPM]":"6.5","Tissue RNA - bone marrow [nTPM]":"3.9","Tissue RNA - breast [nTPM]":"5.6","Tissue RNA - cerebellum [nTPM]":"6.1","Tissue RNA - cerebral cortex [nTPM]":"9.0","Tissue RNA - cervix [nTPM]":"4.0","Tissue RNA - choroid plexus [nTPM]":"8.7","Tissue RNA - colon [nTPM]":"5.7","Tissue RNA - duodenum [nTPM]":"7.2","Tissue RNA - endometrium 1 [nTPM]":"4.4","Tissue RNA - epididymis [nTPM]":"8.5","Tissue RNA - esophagus [nTPM]":"4.2","Tissue RNA - fallopian tube [nTPM]":"4.5","Tissue RNA - gallbladder [nTPM]":"6.8","Tissue RNA - heart muscle [nTPM]":"6.7","Tissue RNA - hippocampal formation [nTPM]":"7.1","Tissue RNA - hypothalamus [nTPM]":"10.2","Tissue RNA - kidney [nTPM]":"8.2","Tissue RNA - liver [nTPM]":"12.0","Tissue RNA - lung [nTPM]":"6.9","Tissue RNA - lymph node [nTPM]":"11.0","Tissue RNA - medulla oblongata [nTPM]":"6.8","Tissue RNA - midbrain [nTPM]":"6.6","Tissue RNA - ovary [nTPM]":"5.8","Tissue RNA - pancreas [nTPM]":"3.8","Tissue RNA - parathyroid gland [nTPM]":"11.3","Tissue RNA - pituitary gland [nTPM]":"5.2","Tissue RNA - placenta [nTPM]":"5.8","Tissue RNA - pons [nTPM]":"6.8","Tissue RNA - prostate [nTPM]":"5.6","Tissue RNA - rectum [nTPM]":"6.6","Tissue RNA - retina [nTPM]":"23.1","Tissue RNA - salivary gland [nTPM]":"4.6","Tissue RNA - seminal vesicle [nTPM]":"5.2","Tissue RNA - skeletal muscle [nTPM]":"7.1","Tissue RNA - skin 1 [nTPM]":"5.3","Tissue RNA - small intestine [nTPM]":"7.0","Tissue RNA - smooth muscle [nTPM]":"6.6","Tissue RNA - spinal cord [nTPM]":"6.1","Tissue RNA - spleen [nTPM]":"8.3","Tissue RNA - stomach 1 [nTPM]":"7.8","Tissue RNA - testis [nTPM]":"9.8","Tissue RNA - thalamus [nTPM]":"7.1","Tissue RNA - thymus [nTPM]":"21.8","Tissue RNA - thyroid gland [nTPM]":"7.7","Tissue RNA - tongue [nTPM]":"6.5","Tissue RNA - tonsil [nTPM]":"8.3","Tissue RNA - urinary bladder [nTPM]":"6.9","Tissue RNA - vagina [nTPM]":"2.3","Tissue RNA - white matter [nTPM]":"7.9","Cell RNA - A-431 [nTPM]":"15.5","Cell RNA - A549 [nTPM]":"5.8","Cell RNA - AF22 [nTPM]":"15.3","Cell RNA - AN3-CA [nTPM]":"10.2","Cell RNA - ASC diff [nTPM]":"12.4","Cell RNA - ASC TERT1 [nTPM]":"13.3","Cell RNA - BEWO [nTPM]":"5.4","Cell RNA - BJ [nTPM]":"14.9","Cell RNA - BJ hTERT+ [nTPM]":"11.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.3","Cell RNA - CACO-2 [nTPM]":"6.9","Cell RNA - CAPAN-2 [nTPM]":"6.7","Cell RNA - Daudi [nTPM]":"26.0","Cell RNA - EFO-21 [nTPM]":"11.9","Cell RNA - fHDF\/TERT166 [nTPM]":"9.8","Cell RNA - GAMG [nTPM]":"13.7","Cell RNA - HaCaT [nTPM]":"6.3","Cell RNA - HAP1 [nTPM]":"10.2","Cell RNA - HBEC3-KT [nTPM]":"9.9","Cell RNA - HBF TERT88 [nTPM]":"19.2","Cell RNA - HDLM-2 [nTPM]":"15.4","Cell RNA - HEK 293 [nTPM]":"9.8","Cell RNA - HEL [nTPM]":"12.3","Cell RNA - HeLa [nTPM]":"13.8","Cell RNA - Hep G2 [nTPM]":"3.6","Cell RNA - HHSteC [nTPM]":"14.8","Cell RNA - HL-60 [nTPM]":"16.6","Cell RNA - HMC-1 [nTPM]":"12.5","Cell RNA - HSkMC [nTPM]":"12.3","Cell RNA - hTCEpi [nTPM]":"16.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.8","Cell RNA - hTERT-HME1 [nTPM]":"9.6","Cell RNA - hTERT-RPE1 [nTPM]":"10.7","Cell RNA - HUVEC TERT2 [nTPM]":"13.5","Cell RNA - JURKAT [nTPM]":"47.0","Cell RNA - K-562 [nTPM]":"4.4","Cell RNA - Karpas-707 [nTPM]":"4.7","Cell RNA - LHCN-M2 [nTPM]":"17.4","Cell RNA - MCF7 [nTPM]":"8.3","Cell RNA - MOLT-4 [nTPM]":"27.7","Cell RNA - NB-4 [nTPM]":"12.1","Cell RNA - NTERA-2 [nTPM]":"3.9","Cell RNA - OE19 [nTPM]":"12.6","Cell RNA - PC-3 [nTPM]":"3.6","Cell RNA - REH [nTPM]":"25.1","Cell RNA - RH-30 [nTPM]":"6.0","Cell RNA - RPMI-8226 [nTPM]":"4.2","Cell RNA - RPTEC TERT1 [nTPM]":"14.6","Cell RNA - RT4 [nTPM]":"9.7","Cell RNA - SCLC-21H [nTPM]":"9.6","Cell RNA - SH-SY5Y [nTPM]":"9.9","Cell RNA - SiHa [nTPM]":"3.3","Cell RNA - SK-BR-3 [nTPM]":"9.0","Cell RNA - SK-MEL-30 [nTPM]":"11.7","Cell RNA - SuSa [nTPM]":"11.7","Cell RNA - T-47d [nTPM]":"7.7","Cell RNA - THP-1 [nTPM]":"25.4","Cell RNA - TIME [nTPM]":"20.1","Cell RNA - U-138 MG [nTPM]":"6.6","Cell RNA - U-2 OS [nTPM]":"7.2","Cell RNA - U-2197 [nTPM]":"7.5","Cell RNA - U-251 MG [nTPM]":"13.5","Cell RNA - U-266\/70 [nTPM]":"12.4","Cell RNA - U-266\/84 [nTPM]":"8.7","Cell RNA - U-698 [nTPM]":"41.7","Cell RNA - U-87 MG [nTPM]":"25.4","Cell RNA - U-937 [nTPM]":"9.4","Cell RNA - WM-115 [nTPM]":"15.2","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"1.6","Blood RNA - eosinophil [nTPM]":"4.8","Blood RNA - gdT-cell [nTPM]":"1.1","Blood RNA - intermediate monocyte [nTPM]":"2.5","Blood RNA - MAIT T-cell [nTPM]":"1.6","Blood RNA - memory B-cell [nTPM]":"1.6","Blood RNA - memory CD4 T-cell [nTPM]":"1.2","Blood RNA - memory CD8 T-cell [nTPM]":"1.2","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"2.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"1.7","Blood RNA - neutrophil [nTPM]":"2.2","Blood RNA - NK-cell [nTPM]":"1.9","Blood RNA - non-classical monocyte [nTPM]":"8.3","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"1.8","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"6.3","Brain RNA - basal ganglia [nTPM]":"6.5","Brain RNA - cerebellum [nTPM]":"6.1","Brain RNA - cerebral cortex [nTPM]":"9.0","Brain RNA - hippocampal formation [nTPM]":"7.1","Brain RNA - hypothalamus [nTPM]":"10.2","Brain RNA - medulla oblongata [nTPM]":"6.8","Brain RNA - midbrain [nTPM]":"6.6","Brain RNA - pons [nTPM]":"6.8","Brain RNA - spinal cord [nTPM]":"6.1","Brain RNA - thalamus [nTPM]":"7.1","Brain RNA - white matter [nTPM]":"7.9","Single Cell Type RNA - Adipocytes [nTPM]":"5.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.5","Single Cell Type RNA - Astrocytes [nTPM]":"13.4","Single Cell Type RNA - B-cells [nTPM]":"9.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"10.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"10.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.3","Single Cell Type RNA - dendritic cells [nTPM]":"7.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"5.3","Single Cell Type RNA - Early spermatids [nTPM]":"11.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.7","Single Cell Type RNA - Endothelial cells [nTPM]":"4.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.0","Single Cell Type RNA - Fibroblasts [nTPM]":"4.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.0","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"3.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.6","Single Cell Type RNA - Hepatocytes [nTPM]":"9.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.8","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"16.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.3","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"7.5","Single Cell Type RNA - Langerhans cells [nTPM]":"3.9","Single Cell Type RNA - Late spermatids [nTPM]":"5.1","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"7.4","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"9.3","Single Cell Type RNA - Muller glia cells [nTPM]":"7.3","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"24.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.9","Single Cell Type RNA - Paneth cells [nTPM]":"6.3","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"6.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.8","Single Cell Type RNA - Spermatocytes [nTPM]":"19.1","Single Cell Type RNA - Spermatogonia [nTPM]":"4.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.8","Single Cell Type RNA - T-cells [nTPM]":"4.1","Single Cell Type RNA - Theca cells [nTPM]":"8.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.9","Single Cell Type RNA - Urothelial cells [nTPM]":"3.7"},{"Gene":"LIMK1","Gene synonym":["LIMK"],"Ensembl":"ENSG00000106683","Gene description":"LIM domain kinase 1","Uniprot":["P53667"],"Chromosome":"7","Position":"74082933-74122525","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Williams-Beuren syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"77.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"27.6","Horizontal cells":"35.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-87 MG":"136.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028516","HPA073571"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Nuclear speckles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA028516":"AB_10601751","HPA073571":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.95e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.79e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.63e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.1","Tissue RNA - adrenal gland [nTPM]":"10.5","Tissue RNA - amygdala [nTPM]":"31.1","Tissue RNA - appendix [nTPM]":"18.7","Tissue RNA - basal ganglia [nTPM]":"32.7","Tissue RNA - bone marrow [nTPM]":"6.8","Tissue RNA - breast [nTPM]":"9.4","Tissue RNA - cerebellum [nTPM]":"28.3","Tissue RNA - cerebral cortex [nTPM]":"77.9","Tissue RNA - cervix [nTPM]":"21.4","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"8.9","Tissue RNA - duodenum [nTPM]":"6.6","Tissue RNA - endometrium 1 [nTPM]":"13.1","Tissue RNA - epididymis [nTPM]":"3.5","Tissue RNA - esophagus [nTPM]":"11.3","Tissue RNA - fallopian tube [nTPM]":"7.3","Tissue RNA - gallbladder [nTPM]":"10.1","Tissue RNA - heart muscle [nTPM]":"9.4","Tissue RNA - hippocampal formation [nTPM]":"35.0","Tissue RNA - hypothalamus [nTPM]":"43.8","Tissue RNA - kidney [nTPM]":"10.8","Tissue RNA - liver [nTPM]":"4.6","Tissue RNA - lung [nTPM]":"13.2","Tissue RNA - lymph node [nTPM]":"23.5","Tissue RNA - medulla oblongata [nTPM]":"75.5","Tissue RNA - midbrain [nTPM]":"40.0","Tissue RNA - ovary [nTPM]":"13.2","Tissue RNA - pancreas [nTPM]":"11.4","Tissue RNA - parathyroid gland [nTPM]":"5.8","Tissue RNA - pituitary gland [nTPM]":"13.9","Tissue RNA - placenta [nTPM]":"7.3","Tissue RNA - pons [nTPM]":"73.0","Tissue RNA - prostate [nTPM]":"12.3","Tissue RNA - rectum [nTPM]":"4.1","Tissue RNA - retina [nTPM]":"4.0","Tissue RNA - salivary gland [nTPM]":"17.9","Tissue RNA - seminal vesicle [nTPM]":"8.2","Tissue RNA - skeletal muscle [nTPM]":"23.7","Tissue RNA - skin 1 [nTPM]":"11.4","Tissue RNA - small intestine [nTPM]":"12.1","Tissue RNA - smooth muscle [nTPM]":"7.1","Tissue RNA - spinal cord [nTPM]":"31.8","Tissue RNA - spleen [nTPM]":"22.3","Tissue RNA - stomach 1 [nTPM]":"9.2","Tissue RNA - testis [nTPM]":"15.6","Tissue RNA - thalamus [nTPM]":"59.1","Tissue RNA - thymus [nTPM]":"8.1","Tissue RNA - thyroid gland [nTPM]":"11.2","Tissue RNA - tongue [nTPM]":"7.8","Tissue RNA - tonsil [nTPM]":"18.2","Tissue RNA - urinary bladder [nTPM]":"13.1","Tissue RNA - vagina [nTPM]":"14.7","Tissue RNA - white matter [nTPM]":"38.3","Cell RNA - A-431 [nTPM]":"47.4","Cell RNA - A549 [nTPM]":"37.2","Cell RNA - AF22 [nTPM]":"27.2","Cell RNA - AN3-CA [nTPM]":"45.4","Cell RNA - ASC diff [nTPM]":"35.1","Cell RNA - ASC TERT1 [nTPM]":"47.0","Cell RNA - BEWO [nTPM]":"20.0","Cell RNA - BJ [nTPM]":"28.8","Cell RNA - BJ hTERT+ [nTPM]":"27.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"22.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"25.4","Cell RNA - CACO-2 [nTPM]":"21.3","Cell RNA - CAPAN-2 [nTPM]":"45.6","Cell RNA - Daudi [nTPM]":"30.2","Cell RNA - EFO-21 [nTPM]":"12.7","Cell RNA - fHDF\/TERT166 [nTPM]":"35.5","Cell RNA - GAMG [nTPM]":"76.9","Cell RNA - HaCaT [nTPM]":"28.1","Cell RNA - HAP1 [nTPM]":"10.1","Cell RNA - HBEC3-KT [nTPM]":"17.8","Cell RNA - HBF TERT88 [nTPM]":"8.6","Cell RNA - HDLM-2 [nTPM]":"53.7","Cell RNA - HEK 293 [nTPM]":"18.6","Cell RNA - HEL [nTPM]":"23.2","Cell RNA - HeLa [nTPM]":"13.1","Cell RNA - Hep G2 [nTPM]":"24.6","Cell RNA - HHSteC [nTPM]":"40.5","Cell RNA - HL-60 [nTPM]":"17.2","Cell RNA - HMC-1 [nTPM]":"81.4","Cell RNA - HSkMC [nTPM]":"46.8","Cell RNA - hTCEpi [nTPM]":"15.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.5","Cell RNA - hTERT-HME1 [nTPM]":"9.6","Cell RNA - hTERT-RPE1 [nTPM]":"68.3","Cell RNA - HUVEC TERT2 [nTPM]":"34.4","Cell RNA - JURKAT [nTPM]":"20.9","Cell RNA - K-562 [nTPM]":"15.1","Cell RNA - Karpas-707 [nTPM]":"9.0","Cell RNA - LHCN-M2 [nTPM]":"28.8","Cell RNA - MCF7 [nTPM]":"41.4","Cell RNA - MOLT-4 [nTPM]":"14.8","Cell RNA - NB-4 [nTPM]":"31.4","Cell RNA - NTERA-2 [nTPM]":"52.1","Cell RNA - OE19 [nTPM]":"16.6","Cell RNA - PC-3 [nTPM]":"23.7","Cell RNA - REH [nTPM]":"21.1","Cell RNA - RH-30 [nTPM]":"43.3","Cell RNA - RPMI-8226 [nTPM]":"18.2","Cell RNA - RPTEC TERT1 [nTPM]":"26.5","Cell RNA - RT4 [nTPM]":"10.1","Cell RNA - SCLC-21H [nTPM]":"10.7","Cell RNA - SH-SY5Y [nTPM]":"25.2","Cell RNA - SiHa [nTPM]":"18.6","Cell RNA - SK-BR-3 [nTPM]":"43.7","Cell RNA - SK-MEL-30 [nTPM]":"23.5","Cell RNA - SuSa [nTPM]":"29.7","Cell RNA - T-47d [nTPM]":"13.9","Cell RNA - THP-1 [nTPM]":"15.4","Cell RNA - TIME [nTPM]":"41.1","Cell RNA - U-138 MG [nTPM]":"36.0","Cell RNA - U-2 OS [nTPM]":"33.7","Cell RNA - U-2197 [nTPM]":"94.5","Cell RNA - U-251 MG [nTPM]":"47.7","Cell RNA - U-266\/70 [nTPM]":"10.2","Cell RNA - U-266\/84 [nTPM]":"12.5","Cell RNA - U-698 [nTPM]":"54.9","Cell RNA - U-87 MG [nTPM]":"136.5","Cell RNA - U-937 [nTPM]":"12.4","Cell RNA - WM-115 [nTPM]":"25.2","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"6.1","Blood RNA - eosinophil [nTPM]":"3.5","Blood RNA - gdT-cell [nTPM]":"1.8","Blood RNA - intermediate monocyte [nTPM]":"6.0","Blood RNA - MAIT T-cell [nTPM]":"1.4","Blood RNA - memory B-cell [nTPM]":"3.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"1.2","Blood RNA - myeloid DC [nTPM]":"7.0","Blood RNA - naive B-cell [nTPM]":"1.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"5.8","Blood RNA - non-classical monocyte [nTPM]":"3.8","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"3.3","Brain RNA - amygdala [nTPM]":"31.1","Brain RNA - basal ganglia [nTPM]":"32.7","Brain RNA - cerebellum [nTPM]":"28.3","Brain RNA - cerebral cortex [nTPM]":"77.9","Brain RNA - hippocampal formation [nTPM]":"35.0","Brain RNA - hypothalamus [nTPM]":"43.8","Brain RNA - medulla oblongata [nTPM]":"75.5","Brain RNA - midbrain [nTPM]":"40.0","Brain RNA - pons [nTPM]":"73.0","Brain RNA - spinal cord [nTPM]":"31.8","Brain RNA - thalamus [nTPM]":"59.1","Brain RNA - white matter [nTPM]":"38.3","Single Cell Type RNA - Adipocytes [nTPM]":"2.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.7","Single Cell Type RNA - Astrocytes [nTPM]":"7.5","Single Cell Type RNA - B-cells [nTPM]":"14.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"6.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"3.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - dendritic cells [nTPM]":"11.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.6","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.7","Single Cell Type RNA - Endothelial cells [nTPM]":"4.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.3","Single Cell Type RNA - Fibroblasts [nTPM]":"9.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.1","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"27.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"2.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.0","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"13.5","Single Cell Type RNA - Langerhans cells [nTPM]":"10.8","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"15.6","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"14.9","Single Cell Type RNA - Muller glia cells [nTPM]":"3.5","Single Cell Type RNA - NK-cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.5","Single Cell Type RNA - Paneth cells [nTPM]":"2.3","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"10.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.5","Single Cell Type RNA - Spermatocytes [nTPM]":"3.4","Single Cell Type RNA - Spermatogonia [nTPM]":"11.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.7","Single Cell Type RNA - T-cells [nTPM]":"11.1","Single Cell Type RNA - Theca cells [nTPM]":"6.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.4","Single Cell Type RNA - Urothelial cells [nTPM]":"7.2"},{"Gene":"LINGO1","Gene synonym":["FLJ14594","LERN1","LRRN6A"],"Ensembl":"ENSG00000169783","Gene description":"Leucine rich repeat and Ig domain containing 1","Uniprot":["Q96FE5"],"Chromosome":"15","Position":"77613027-77820900","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"56.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"271.0","Excitatory neurons":"271.6","Horizontal cells":"132.9","Inhibitory neurons":"220.5","Microglial cells":"167.7","Oligodendrocyte precursor cells":"240.8","Oligodendrocytes":"324.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"10","RNA brain regional specific nTPM":{"amygdala":"37.4","basal ganglia":"43.9","cerebral cortex":"56.1","hippocampal formation":"49.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"23.9","AN3-CA":"20.1","HAP1":"30.2","HEK 293":"21.0","MCF7":"13.5","NTERA-2":"56.9","SuSa":"21.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074653"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"25000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA074653":"AB_2686706"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.23e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.9","Tissue RNA - adrenal gland [nTPM]":"1.1","Tissue RNA - amygdala [nTPM]":"37.4","Tissue RNA - appendix [nTPM]":"1.2","Tissue RNA - basal ganglia [nTPM]":"43.9","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"3.5","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"56.1","Tissue RNA - cervix [nTPM]":"4.6","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"2.2","Tissue RNA - duodenum [nTPM]":"1.5","Tissue RNA - endometrium 1 [nTPM]":"4.5","Tissue RNA - epididymis [nTPM]":"2.2","Tissue RNA - esophagus [nTPM]":"0.9","Tissue RNA - fallopian tube [nTPM]":"2.7","Tissue RNA - gallbladder [nTPM]":"2.1","Tissue RNA - heart muscle [nTPM]":"11.8","Tissue RNA - hippocampal formation [nTPM]":"49.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"4.2","Tissue RNA - liver [nTPM]":"0.8","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"0.7","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"2.3","Tissue RNA - pancreas [nTPM]":"2.5","Tissue RNA - parathyroid gland [nTPM]":"4.1","Tissue RNA - pituitary gland [nTPM]":"1.9","Tissue RNA - placenta [nTPM]":"6.7","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"1.6","Tissue RNA - rectum [nTPM]":"0.8","Tissue RNA - retina [nTPM]":"16.2","Tissue RNA - salivary gland [nTPM]":"3.2","Tissue RNA - seminal vesicle [nTPM]":"2.0","Tissue RNA - skeletal muscle [nTPM]":"0.8","Tissue RNA - skin 1 [nTPM]":"2.8","Tissue RNA - small intestine [nTPM]":"1.7","Tissue RNA - smooth muscle [nTPM]":"4.6","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"3.3","Tissue RNA - stomach 1 [nTPM]":"1.4","Tissue RNA - testis [nTPM]":"5.3","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"2.2","Tissue RNA - tongue [nTPM]":"1.4","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"2.3","Tissue RNA - vagina [nTPM]":"2.9","Tissue RNA - white matter [nTPM]":"4.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"2.1","Cell RNA - AF22 [nTPM]":"23.9","Cell RNA - AN3-CA [nTPM]":"20.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"1.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"30.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"21.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.4","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"3.3","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"13.5","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"56.9","Cell RNA - OE19 [nTPM]":"1.3","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"4.2","Cell RNA - SH-SY5Y [nTPM]":"1.2","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"2.4","Cell RNA - SK-MEL-30 [nTPM]":"4.9","Cell RNA - SuSa [nTPM]":"21.6","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"2.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"5.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"37.4","Brain RNA - basal ganglia [nTPM]":"43.9","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"56.1","Brain RNA - hippocampal formation [nTPM]":"49.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"4.6","Single Cell Type RNA - Adipocytes [nTPM]":"2.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"271.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"21.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"8.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.7","Single Cell Type RNA - Endothelial cells [nTPM]":"2.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"271.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"1.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"14.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"132.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"220.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"16.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"167.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"51.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"240.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"324.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"7.7","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.5","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"3.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"LIPA","Gene synonym":["CESD","LAL"],"Ensembl":"ENSG00000107798","Gene description":"Lipase A, lysosomal acid type","Uniprot":["P38571"],"Chromosome":"10","Position":"89213569-89414557","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"398.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"515.0","Kupffer cells":"714.8","Macrophages":"303.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"167.3","intermediate monocyte":"355.1","myeloid DC":"123.6","non-classical monocyte":"198.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"123.6","monocytes":"355.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"354.4","AN3-CA":"367.8","ASC TERT1":"450.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034892","HPA057052"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Vesicles","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"280000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":["Nucleoplasm","Nucleoli fibrillar center"],"Antibody RRID":{"CAB034892":"AB_784329","HPA057052":"AB_2683322"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Tissue RNA - adipose tissue [nTPM]":"76.0","Tissue RNA - adrenal gland [nTPM]":"46.3","Tissue RNA - amygdala [nTPM]":"43.5","Tissue RNA - appendix [nTPM]":"66.7","Tissue RNA - basal ganglia [nTPM]":"65.2","Tissue RNA - bone marrow [nTPM]":"39.8","Tissue RNA - breast [nTPM]":"47.8","Tissue RNA - cerebellum [nTPM]":"64.1","Tissue RNA - cerebral cortex [nTPM]":"74.4","Tissue RNA - cervix [nTPM]":"54.0","Tissue RNA - choroid plexus [nTPM]":"39.0","Tissue RNA - colon [nTPM]":"67.7","Tissue RNA - duodenum [nTPM]":"167.6","Tissue RNA - endometrium 1 [nTPM]":"38.8","Tissue RNA - epididymis [nTPM]":"21.7","Tissue RNA - esophagus [nTPM]":"28.6","Tissue RNA - fallopian tube [nTPM]":"37.8","Tissue RNA - gallbladder [nTPM]":"83.5","Tissue RNA - heart muscle [nTPM]":"24.2","Tissue RNA - hippocampal formation [nTPM]":"43.5","Tissue RNA - hypothalamus [nTPM]":"53.1","Tissue RNA - kidney [nTPM]":"44.9","Tissue RNA - liver [nTPM]":"218.9","Tissue RNA - lung [nTPM]":"169.5","Tissue RNA - lymph node [nTPM]":"159.3","Tissue RNA - medulla oblongata [nTPM]":"74.7","Tissue RNA - midbrain [nTPM]":"55.5","Tissue RNA - ovary [nTPM]":"32.7","Tissue RNA - pancreas [nTPM]":"21.4","Tissue RNA - parathyroid gland [nTPM]":"68.9","Tissue RNA - pituitary gland [nTPM]":"12.7","Tissue RNA - placenta [nTPM]":"79.1","Tissue RNA - pons [nTPM]":"82.2","Tissue RNA - prostate [nTPM]":"30.7","Tissue RNA - rectum [nTPM]":"72.0","Tissue RNA - retina [nTPM]":"12.6","Tissue RNA - salivary gland [nTPM]":"22.5","Tissue RNA - seminal vesicle [nTPM]":"33.8","Tissue RNA - skeletal muscle [nTPM]":"11.8","Tissue RNA - skin 1 [nTPM]":"18.7","Tissue RNA - small intestine [nTPM]":"227.5","Tissue RNA - smooth muscle [nTPM]":"47.7","Tissue RNA - spinal cord [nTPM]":"65.4","Tissue RNA - spleen [nTPM]":"398.4","Tissue RNA - stomach 1 [nTPM]":"34.3","Tissue RNA - testis [nTPM]":"13.4","Tissue RNA - thalamus [nTPM]":"57.0","Tissue RNA - thymus [nTPM]":"44.5","Tissue RNA - thyroid gland [nTPM]":"31.6","Tissue RNA - tongue [nTPM]":"22.5","Tissue RNA - tonsil [nTPM]":"45.5","Tissue RNA - urinary bladder [nTPM]":"58.4","Tissue RNA - vagina [nTPM]":"19.3","Tissue RNA - white matter [nTPM]":"115.5","Cell RNA - A-431 [nTPM]":"354.4","Cell RNA - A549 [nTPM]":"49.4","Cell RNA - AF22 [nTPM]":"30.7","Cell RNA - AN3-CA [nTPM]":"367.8","Cell RNA - ASC diff [nTPM]":"343.5","Cell RNA - ASC TERT1 [nTPM]":"450.8","Cell RNA - BEWO [nTPM]":"10.0","Cell RNA - BJ [nTPM]":"171.4","Cell RNA - BJ hTERT+ [nTPM]":"194.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"65.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"121.5","Cell RNA - CACO-2 [nTPM]":"18.6","Cell RNA - CAPAN-2 [nTPM]":"176.6","Cell RNA - Daudi [nTPM]":"63.9","Cell RNA - EFO-21 [nTPM]":"34.0","Cell RNA - fHDF\/TERT166 [nTPM]":"264.4","Cell RNA - GAMG [nTPM]":"73.7","Cell RNA - HaCaT [nTPM]":"338.7","Cell RNA - HAP1 [nTPM]":"13.8","Cell RNA - HBEC3-KT [nTPM]":"92.8","Cell RNA - HBF TERT88 [nTPM]":"53.6","Cell RNA - HDLM-2 [nTPM]":"86.1","Cell RNA - HEK 293 [nTPM]":"34.7","Cell RNA - HEL [nTPM]":"25.1","Cell RNA - HeLa [nTPM]":"19.1","Cell RNA - Hep G2 [nTPM]":"81.5","Cell RNA - HHSteC [nTPM]":"87.6","Cell RNA - HL-60 [nTPM]":"48.8","Cell RNA - HMC-1 [nTPM]":"48.9","Cell RNA - HSkMC [nTPM]":"190.4","Cell RNA - hTCEpi [nTPM]":"69.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"72.9","Cell RNA - hTERT-HME1 [nTPM]":"40.6","Cell RNA - hTERT-RPE1 [nTPM]":"88.2","Cell RNA - HUVEC TERT2 [nTPM]":"14.9","Cell RNA - JURKAT [nTPM]":"45.4","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"108.5","Cell RNA - LHCN-M2 [nTPM]":"58.3","Cell RNA - MCF7 [nTPM]":"28.2","Cell RNA - MOLT-4 [nTPM]":"45.7","Cell RNA - NB-4 [nTPM]":"34.6","Cell RNA - NTERA-2 [nTPM]":"22.7","Cell RNA - OE19 [nTPM]":"62.4","Cell RNA - PC-3 [nTPM]":"60.0","Cell RNA - REH [nTPM]":"26.4","Cell RNA - RH-30 [nTPM]":"39.0","Cell RNA - RPMI-8226 [nTPM]":"60.5","Cell RNA - RPTEC TERT1 [nTPM]":"69.2","Cell RNA - RT4 [nTPM]":"50.9","Cell RNA - SCLC-21H [nTPM]":"10.5","Cell RNA - SH-SY5Y [nTPM]":"21.8","Cell RNA - SiHa [nTPM]":"41.4","Cell RNA - SK-BR-3 [nTPM]":"49.9","Cell RNA - SK-MEL-30 [nTPM]":"133.9","Cell RNA - SuSa [nTPM]":"20.4","Cell RNA - T-47d [nTPM]":"64.4","Cell RNA - THP-1 [nTPM]":"65.8","Cell RNA - TIME [nTPM]":"26.2","Cell RNA - U-138 MG [nTPM]":"58.8","Cell RNA - U-2 OS [nTPM]":"15.5","Cell RNA - U-2197 [nTPM]":"132.1","Cell RNA - U-251 MG [nTPM]":"44.6","Cell RNA - U-266\/70 [nTPM]":"60.0","Cell RNA - U-266\/84 [nTPM]":"65.7","Cell RNA - U-698 [nTPM]":"25.8","Cell RNA - U-87 MG [nTPM]":"71.4","Cell RNA - U-937 [nTPM]":"112.9","Cell RNA - WM-115 [nTPM]":"82.1","Blood RNA - basophil [nTPM]":"4.2","Blood RNA - classical monocyte [nTPM]":"167.3","Blood RNA - eosinophil [nTPM]":"16.9","Blood RNA - gdT-cell [nTPM]":"40.0","Blood RNA - intermediate monocyte [nTPM]":"355.1","Blood RNA - MAIT T-cell [nTPM]":"40.6","Blood RNA - memory B-cell [nTPM]":"31.9","Blood RNA - memory CD4 T-cell [nTPM]":"35.8","Blood RNA - memory CD8 T-cell [nTPM]":"38.8","Blood RNA - myeloid DC [nTPM]":"123.6","Blood RNA - naive B-cell [nTPM]":"33.4","Blood RNA - naive CD4 T-cell [nTPM]":"36.7","Blood RNA - naive CD8 T-cell [nTPM]":"40.4","Blood RNA - neutrophil [nTPM]":"7.1","Blood RNA - NK-cell [nTPM]":"29.8","Blood RNA - non-classical monocyte [nTPM]":"198.5","Blood RNA - plasmacytoid DC [nTPM]":"25.0","Blood RNA - T-reg [nTPM]":"38.2","Blood RNA - total PBMC [nTPM]":"159.6","Brain RNA - amygdala [nTPM]":"43.5","Brain RNA - basal ganglia [nTPM]":"65.2","Brain RNA - cerebellum [nTPM]":"64.1","Brain RNA - cerebral cortex [nTPM]":"74.4","Brain RNA - hippocampal formation [nTPM]":"43.5","Brain RNA - hypothalamus [nTPM]":"53.1","Brain RNA - medulla oblongata [nTPM]":"74.7","Brain RNA - midbrain [nTPM]":"55.5","Brain RNA - pons [nTPM]":"82.2","Brain RNA - spinal cord [nTPM]":"65.4","Brain RNA - thalamus [nTPM]":"57.0","Brain RNA - white matter [nTPM]":"115.5","Single Cell Type RNA - Adipocytes [nTPM]":"75.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"33.8","Single Cell Type RNA - Astrocytes [nTPM]":"11.1","Single Cell Type RNA - B-cells [nTPM]":"35.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"30.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"58.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.6","Single Cell Type RNA - Bipolar cells [nTPM]":"5.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"45.8","Single Cell Type RNA - Club cells [nTPM]":"31.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"34.8","Single Cell Type RNA - dendritic cells [nTPM]":"31.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"35.1","Single Cell Type RNA - Early spermatids [nTPM]":"6.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.4","Single Cell Type RNA - Endothelial cells [nTPM]":"56.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.8","Single Cell Type RNA - Erythroid cells [nTPM]":"27.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"34.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"36.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"32.9","Single Cell Type RNA - Fibroblasts [nTPM]":"34.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.5","Single Cell Type RNA - granulocytes [nTPM]":"28.5","Single Cell Type RNA - Granulosa cells [nTPM]":"10.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"54.7","Single Cell Type RNA - Hepatocytes [nTPM]":"66.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"515.0","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.9","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"714.8","Single Cell Type RNA - Langerhans cells [nTPM]":"69.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.7","Single Cell Type RNA - Leydig cells [nTPM]":"11.5","Single Cell Type RNA - Macrophages [nTPM]":"303.1","Single Cell Type RNA - Melanocytes [nTPM]":"48.0","Single Cell Type RNA - Microglial cells [nTPM]":"30.0","Single Cell Type RNA - monocytes [nTPM]":"71.7","Single Cell Type RNA - Muller glia cells [nTPM]":"33.1","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"143.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.3","Single Cell Type RNA - Paneth cells [nTPM]":"12.0","Single Cell Type RNA - Peritubular cells [nTPM]":"21.8","Single Cell Type RNA - Plasma cells [nTPM]":"15.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"161.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.0","Single Cell Type RNA - Spermatocytes [nTPM]":"5.1","Single Cell Type RNA - Spermatogonia [nTPM]":"13.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"31.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.0","Single Cell Type RNA - T-cells [nTPM]":"33.1","Single Cell Type RNA - Theca cells [nTPM]":"17.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.1","Single Cell Type RNA - Urothelial cells [nTPM]":"24.0"},{"Gene":"LIPC","Gene synonym":["HL","HTGL"],"Ensembl":"ENSG00000166035","Gene description":"Lipase C, hepatic type","Uniprot":["P11150"],"Chromosome":"15","Position":"58410569-58569844","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted secreted proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Heparin-binding","Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"28","RNA tissue specific nTPM":{"liver":"171.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Hepatocytes":"161.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"14","RNA cancer specific FPKM":{"liver cancer":"20.4","renal cancer":"10.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"1.6","NK-cells":"1.5","T-cells":"1.8"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"8.5","EFO-21":"6.1","Hep G2":"24.4","HMC-1":"6.8","MOLT-4":"5.5","U-2197":"18.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5500000","Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.15e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.93e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"1.5","Tissue RNA - cerebellum [nTPM]":"0.8","Tissue RNA - cerebral cortex [nTPM]":"0.9","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.6","Tissue RNA - duodenum [nTPM]":"1.8","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"0.6","Tissue RNA - fallopian tube [nTPM]":"1.0","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"0.6","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"6.0","Tissue RNA - liver [nTPM]":"171.0","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.7","Tissue RNA - medulla oblongata [nTPM]":"0.8","Tissue RNA - midbrain [nTPM]":"0.7","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"2.5","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.5","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"1.0","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.8","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.9","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"0.8","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"0.8","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"2.1","Tissue RNA - thyroid gland [nTPM]":"1.2","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"1.6","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"1.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.3","Cell RNA - ASC TERT1 [nTPM]":"1.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"8.5","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"6.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"3.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"24.4","Cell RNA - HHSteC [nTPM]":"0.5","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"6.8","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"1.2","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"5.5","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"1.1","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"2.6","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"18.4","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.5","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"1.6","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.3","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"1.8","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"1.3","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.9","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"0.8","Brain RNA - cerebral cortex [nTPM]":"0.9","Brain RNA - hippocampal formation [nTPM]":"0.6","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.8","Brain RNA - midbrain [nTPM]":"0.7","Brain RNA - pons [nTPM]":"1.0","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"1.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"0.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"1.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"2.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.2","Single Cell Type RNA - Hepatocytes [nTPM]":"161.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"1.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"LIPE","Gene synonym":["HSL"],"Ensembl":"ENSG00000079435","Gene description":"Lipase E, hormone sensitive type","Uniprot":["Q05469"],"Chromosome":"19","Position":"42401514-42427388","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cholesterol metabolism","Lipid degradation","Lipid metabolism","Steroid metabolism","Sterol metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Diabetes mellitus","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"adipose tissue":"834.5","breast":"524.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"76.1","Early spermatids":"127.8","Late spermatids":"236.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"ASC diff":"136.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006567","CAB017700"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB017700":"AB_2135504","HPA006567":"AB_2667618"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.15e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-3"},"Tissue RNA - adipose tissue [nTPM]":"834.5","Tissue RNA - adrenal gland [nTPM]":"45.1","Tissue RNA - amygdala [nTPM]":"22.7","Tissue RNA - appendix [nTPM]":"7.7","Tissue RNA - basal ganglia [nTPM]":"71.7","Tissue RNA - bone marrow [nTPM]":"5.0","Tissue RNA - breast [nTPM]":"524.7","Tissue RNA - cerebellum [nTPM]":"77.2","Tissue RNA - cerebral cortex [nTPM]":"41.5","Tissue RNA - cervix [nTPM]":"5.1","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"10.9","Tissue RNA - duodenum [nTPM]":"5.3","Tissue RNA - endometrium 1 [nTPM]":"6.4","Tissue RNA - epididymis [nTPM]":"1.2","Tissue RNA - esophagus [nTPM]":"8.6","Tissue RNA - fallopian tube [nTPM]":"5.8","Tissue RNA - gallbladder [nTPM]":"3.7","Tissue RNA - heart muscle [nTPM]":"32.5","Tissue RNA - hippocampal formation [nTPM]":"23.8","Tissue RNA - hypothalamus [nTPM]":"42.6","Tissue RNA - kidney [nTPM]":"7.7","Tissue RNA - liver [nTPM]":"1.5","Tissue RNA - lung [nTPM]":"3.7","Tissue RNA - lymph node [nTPM]":"7.3","Tissue RNA - medulla oblongata [nTPM]":"100.3","Tissue RNA - midbrain [nTPM]":"73.9","Tissue RNA - ovary [nTPM]":"4.9","Tissue RNA - pancreas [nTPM]":"6.2","Tissue RNA - parathyroid gland [nTPM]":"4.7","Tissue RNA - pituitary gland [nTPM]":"6.9","Tissue RNA - placenta [nTPM]":"2.9","Tissue RNA - pons [nTPM]":"90.0","Tissue RNA - prostate [nTPM]":"7.1","Tissue RNA - rectum [nTPM]":"1.4","Tissue RNA - retina [nTPM]":"2.0","Tissue RNA - salivary gland [nTPM]":"17.2","Tissue RNA - seminal vesicle [nTPM]":"2.6","Tissue RNA - skeletal muscle [nTPM]":"19.7","Tissue RNA - skin 1 [nTPM]":"23.6","Tissue RNA - small intestine [nTPM]":"24.4","Tissue RNA - smooth muscle [nTPM]":"2.6","Tissue RNA - spinal cord [nTPM]":"44.0","Tissue RNA - spleen [nTPM]":"14.4","Tissue RNA - stomach 1 [nTPM]":"8.5","Tissue RNA - testis [nTPM]":"68.6","Tissue RNA - thalamus [nTPM]":"57.1","Tissue RNA - thymus [nTPM]":"6.9","Tissue RNA - thyroid gland [nTPM]":"9.6","Tissue RNA - tongue [nTPM]":"23.3","Tissue RNA - tonsil [nTPM]":"3.7","Tissue RNA - urinary bladder [nTPM]":"14.2","Tissue RNA - vagina [nTPM]":"7.7","Tissue RNA - white matter [nTPM]":"116.9","Cell RNA - A-431 [nTPM]":"12.7","Cell RNA - A549 [nTPM]":"9.6","Cell RNA - AF22 [nTPM]":"6.0","Cell RNA - AN3-CA [nTPM]":"2.3","Cell RNA - ASC diff [nTPM]":"136.8","Cell RNA - ASC TERT1 [nTPM]":"1.3","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"5.8","Cell RNA - BJ hTERT+ [nTPM]":"3.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.5","Cell RNA - CACO-2 [nTPM]":"2.3","Cell RNA - CAPAN-2 [nTPM]":"4.6","Cell RNA - Daudi [nTPM]":"20.6","Cell RNA - EFO-21 [nTPM]":"6.3","Cell RNA - fHDF\/TERT166 [nTPM]":"1.8","Cell RNA - GAMG [nTPM]":"4.5","Cell RNA - HaCaT [nTPM]":"5.6","Cell RNA - HAP1 [nTPM]":"3.7","Cell RNA - HBEC3-KT [nTPM]":"11.5","Cell RNA - HBF TERT88 [nTPM]":"1.0","Cell RNA - HDLM-2 [nTPM]":"4.0","Cell RNA - HEK 293 [nTPM]":"6.1","Cell RNA - HEL [nTPM]":"5.8","Cell RNA - HeLa [nTPM]":"5.3","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"2.7","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"13.9","Cell RNA - HSkMC [nTPM]":"1.2","Cell RNA - hTCEpi [nTPM]":"10.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.5","Cell RNA - hTERT-HME1 [nTPM]":"2.1","Cell RNA - hTERT-RPE1 [nTPM]":"1.3","Cell RNA - HUVEC TERT2 [nTPM]":"2.6","Cell RNA - JURKAT [nTPM]":"8.5","Cell RNA - K-562 [nTPM]":"2.7","Cell RNA - Karpas-707 [nTPM]":"12.8","Cell RNA - LHCN-M2 [nTPM]":"1.2","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"14.8","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"9.7","Cell RNA - PC-3 [nTPM]":"2.7","Cell RNA - REH [nTPM]":"12.2","Cell RNA - RH-30 [nTPM]":"1.1","Cell RNA - RPMI-8226 [nTPM]":"6.9","Cell RNA - RPTEC TERT1 [nTPM]":"2.6","Cell RNA - RT4 [nTPM]":"13.1","Cell RNA - SCLC-21H [nTPM]":"8.5","Cell RNA - SH-SY5Y [nTPM]":"8.8","Cell RNA - SiHa [nTPM]":"5.1","Cell RNA - SK-BR-3 [nTPM]":"5.7","Cell RNA - SK-MEL-30 [nTPM]":"5.6","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"1.5","Cell RNA - THP-1 [nTPM]":"7.5","Cell RNA - TIME [nTPM]":"4.7","Cell RNA - U-138 MG [nTPM]":"2.5","Cell RNA - U-2 OS [nTPM]":"7.8","Cell RNA - U-2197 [nTPM]":"1.1","Cell RNA - U-251 MG [nTPM]":"5.3","Cell RNA - U-266\/70 [nTPM]":"9.7","Cell RNA - U-266\/84 [nTPM]":"8.5","Cell RNA - U-698 [nTPM]":"15.6","Cell RNA - U-87 MG [nTPM]":"6.3","Cell RNA - U-937 [nTPM]":"0.7","Cell RNA - WM-115 [nTPM]":"8.7","Blood RNA - basophil [nTPM]":"11.0","Blood RNA - classical monocyte [nTPM]":"8.6","Blood RNA - eosinophil [nTPM]":"3.8","Blood RNA - gdT-cell [nTPM]":"2.5","Blood RNA - intermediate monocyte [nTPM]":"4.7","Blood RNA - MAIT T-cell [nTPM]":"2.3","Blood RNA - memory B-cell [nTPM]":"3.4","Blood RNA - memory CD4 T-cell [nTPM]":"3.2","Blood RNA - memory CD8 T-cell [nTPM]":"3.7","Blood RNA - myeloid DC [nTPM]":"3.6","Blood RNA - naive B-cell [nTPM]":"4.5","Blood RNA - naive CD4 T-cell [nTPM]":"2.8","Blood RNA - naive CD8 T-cell [nTPM]":"2.5","Blood RNA - neutrophil [nTPM]":"1.5","Blood RNA - NK-cell [nTPM]":"3.6","Blood RNA - non-classical monocyte [nTPM]":"2.7","Blood RNA - plasmacytoid DC [nTPM]":"2.9","Blood RNA - T-reg [nTPM]":"3.0","Blood RNA - total PBMC [nTPM]":"3.1","Brain RNA - amygdala [nTPM]":"22.7","Brain RNA - basal ganglia [nTPM]":"71.7","Brain RNA - cerebellum [nTPM]":"77.2","Brain RNA - cerebral cortex [nTPM]":"41.5","Brain RNA - hippocampal formation [nTPM]":"23.8","Brain RNA - hypothalamus [nTPM]":"42.6","Brain RNA - medulla oblongata [nTPM]":"100.3","Brain RNA - midbrain [nTPM]":"73.9","Brain RNA - pons [nTPM]":"90.0","Brain RNA - spinal cord [nTPM]":"44.0","Brain RNA - thalamus [nTPM]":"57.1","Brain RNA - white matter [nTPM]":"116.9","Single Cell Type RNA - Adipocytes [nTPM]":"76.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.3","Single Cell Type RNA - Astrocytes [nTPM]":"4.2","Single Cell Type RNA - B-cells [nTPM]":"8.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"11.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"4.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.0","Single Cell Type RNA - Early spermatids [nTPM]":"127.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.4","Single Cell Type RNA - Endothelial cells [nTPM]":"10.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"2.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"6.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.9","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"2.2","Single Cell Type RNA - Langerhans cells [nTPM]":"2.4","Single Cell Type RNA - Late spermatids [nTPM]":"236.5","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"0.9","Single Cell Type RNA - Muller glia cells [nTPM]":"4.0","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"37.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.7","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"3.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.1","Single Cell Type RNA - Spermatocytes [nTPM]":"39.4","Single Cell Type RNA - Spermatogonia [nTPM]":"13.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"5.1","Single Cell Type RNA - Theca cells [nTPM]":"5.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.9","Single Cell Type RNA - Urothelial cells [nTPM]":"10.7"},{"Gene":"LIPT2","Gene synonym":[],"Ensembl":"ENSG00000175536","Gene description":"Lipoyl(octanoyl) transferase 2","Uniprot":["A6NK58"],"Chromosome":"11","Position":"74490519-74493724","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Ligase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"12.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"55.4","Late spermatids":"29.4","Proximal tubular cells":"17.7","Spermatocytes":"46.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040249"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA040249":"AB_10795275"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.63e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.3","Tissue RNA - adrenal gland [nTPM]":"2.0","Tissue RNA - amygdala [nTPM]":"1.8","Tissue RNA - appendix [nTPM]":"1.6","Tissue RNA - basal ganglia [nTPM]":"2.0","Tissue RNA - bone marrow [nTPM]":"2.1","Tissue RNA - breast [nTPM]":"2.4","Tissue RNA - cerebellum [nTPM]":"1.8","Tissue RNA - cerebral cortex [nTPM]":"1.8","Tissue RNA - cervix [nTPM]":"1.5","Tissue RNA - choroid plexus [nTPM]":"1.2","Tissue RNA - colon [nTPM]":"2.1","Tissue RNA - duodenum [nTPM]":"3.7","Tissue RNA - endometrium 1 [nTPM]":"1.6","Tissue RNA - epididymis [nTPM]":"3.2","Tissue RNA - esophagus [nTPM]":"1.8","Tissue RNA - fallopian tube [nTPM]":"3.2","Tissue RNA - gallbladder [nTPM]":"1.9","Tissue RNA - heart muscle [nTPM]":"1.5","Tissue RNA - hippocampal formation [nTPM]":"1.6","Tissue RNA - hypothalamus [nTPM]":"1.8","Tissue RNA - kidney [nTPM]":"4.6","Tissue RNA - liver [nTPM]":"3.1","Tissue RNA - lung [nTPM]":"1.7","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"2.4","Tissue RNA - midbrain [nTPM]":"1.9","Tissue RNA - ovary [nTPM]":"3.4","Tissue RNA - pancreas [nTPM]":"2.9","Tissue RNA - parathyroid gland [nTPM]":"2.1","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"2.1","Tissue RNA - pons [nTPM]":"2.4","Tissue RNA - prostate [nTPM]":"1.8","Tissue RNA - rectum [nTPM]":"2.3","Tissue RNA - retina [nTPM]":"1.9","Tissue RNA - salivary gland [nTPM]":"2.1","Tissue RNA - seminal vesicle [nTPM]":"2.7","Tissue RNA - skeletal muscle [nTPM]":"8.0","Tissue RNA - skin 1 [nTPM]":"1.6","Tissue RNA - small intestine [nTPM]":"3.6","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"1.8","Tissue RNA - spleen [nTPM]":"2.1","Tissue RNA - stomach 1 [nTPM]":"3.5","Tissue RNA - testis [nTPM]":"12.3","Tissue RNA - thalamus [nTPM]":"2.8","Tissue RNA - thymus [nTPM]":"2.7","Tissue RNA - thyroid gland [nTPM]":"3.0","Tissue RNA - tongue [nTPM]":"7.1","Tissue RNA - tonsil [nTPM]":"2.2","Tissue RNA - urinary bladder [nTPM]":"1.7","Tissue RNA - vagina [nTPM]":"1.2","Tissue RNA - white matter [nTPM]":"3.3","Cell RNA - A-431 [nTPM]":"2.1","Cell RNA - A549 [nTPM]":"3.3","Cell RNA - AF22 [nTPM]":"6.6","Cell RNA - AN3-CA [nTPM]":"3.1","Cell RNA - ASC diff [nTPM]":"2.1","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"6.9","Cell RNA - BJ [nTPM]":"0.8","Cell RNA - BJ hTERT+ [nTPM]":"1.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.3","Cell RNA - CACO-2 [nTPM]":"9.8","Cell RNA - CAPAN-2 [nTPM]":"3.0","Cell RNA - Daudi [nTPM]":"11.5","Cell RNA - EFO-21 [nTPM]":"4.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.6","Cell RNA - GAMG [nTPM]":"8.0","Cell RNA - HaCaT [nTPM]":"3.2","Cell RNA - HAP1 [nTPM]":"2.8","Cell RNA - HBEC3-KT [nTPM]":"1.9","Cell RNA - HBF TERT88 [nTPM]":"1.2","Cell RNA - HDLM-2 [nTPM]":"2.2","Cell RNA - HEK 293 [nTPM]":"2.6","Cell RNA - HEL [nTPM]":"4.0","Cell RNA - HeLa [nTPM]":"3.2","Cell RNA - Hep G2 [nTPM]":"2.9","Cell RNA - HHSteC [nTPM]":"2.9","Cell RNA - HL-60 [nTPM]":"4.4","Cell RNA - HMC-1 [nTPM]":"5.0","Cell RNA - HSkMC [nTPM]":"1.4","Cell RNA - hTCEpi [nTPM]":"2.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.2","Cell RNA - hTERT-HME1 [nTPM]":"2.2","Cell RNA - hTERT-RPE1 [nTPM]":"1.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"12.7","Cell RNA - K-562 [nTPM]":"3.0","Cell RNA - Karpas-707 [nTPM]":"4.1","Cell RNA - LHCN-M2 [nTPM]":"1.3","Cell RNA - MCF7 [nTPM]":"4.0","Cell RNA - MOLT-4 [nTPM]":"6.6","Cell RNA - NB-4 [nTPM]":"6.1","Cell RNA - NTERA-2 [nTPM]":"4.9","Cell RNA - OE19 [nTPM]":"13.0","Cell RNA - PC-3 [nTPM]":"2.6","Cell RNA - REH [nTPM]":"4.3","Cell RNA - RH-30 [nTPM]":"7.0","Cell RNA - RPMI-8226 [nTPM]":"3.7","Cell RNA - RPTEC TERT1 [nTPM]":"2.6","Cell RNA - RT4 [nTPM]":"7.3","Cell RNA - SCLC-21H [nTPM]":"5.5","Cell RNA - SH-SY5Y [nTPM]":"3.6","Cell RNA - SiHa [nTPM]":"5.6","Cell RNA - SK-BR-3 [nTPM]":"2.0","Cell RNA - SK-MEL-30 [nTPM]":"8.1","Cell RNA - SuSa [nTPM]":"6.2","Cell RNA - T-47d [nTPM]":"5.6","Cell RNA - THP-1 [nTPM]":"3.2","Cell RNA - TIME [nTPM]":"0.6","Cell RNA - U-138 MG [nTPM]":"1.0","Cell RNA - U-2 OS [nTPM]":"2.1","Cell RNA - U-2197 [nTPM]":"1.5","Cell RNA - U-251 MG [nTPM]":"1.8","Cell RNA - U-266\/70 [nTPM]":"5.7","Cell RNA - U-266\/84 [nTPM]":"5.8","Cell RNA - U-698 [nTPM]":"9.3","Cell RNA - U-87 MG [nTPM]":"0.6","Cell RNA - U-937 [nTPM]":"2.7","Cell RNA - WM-115 [nTPM]":"2.9","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"4.7","Blood RNA - eosinophil [nTPM]":"7.5","Blood RNA - gdT-cell [nTPM]":"5.5","Blood RNA - intermediate monocyte [nTPM]":"3.0","Blood RNA - MAIT T-cell [nTPM]":"7.6","Blood RNA - memory B-cell [nTPM]":"10.6","Blood RNA - memory CD4 T-cell [nTPM]":"7.3","Blood RNA - memory CD8 T-cell [nTPM]":"6.6","Blood RNA - myeloid DC [nTPM]":"5.3","Blood RNA - naive B-cell [nTPM]":"10.5","Blood RNA - naive CD4 T-cell [nTPM]":"13.3","Blood RNA - naive CD8 T-cell [nTPM]":"10.9","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"8.4","Blood RNA - non-classical monocyte [nTPM]":"3.4","Blood RNA - plasmacytoid DC [nTPM]":"6.3","Blood RNA - T-reg [nTPM]":"3.7","Blood RNA - total PBMC [nTPM]":"4.8","Brain RNA - amygdala [nTPM]":"1.8","Brain RNA - basal ganglia [nTPM]":"2.0","Brain RNA - cerebellum [nTPM]":"1.8","Brain RNA - cerebral cortex [nTPM]":"1.8","Brain RNA - hippocampal formation [nTPM]":"1.6","Brain RNA - hypothalamus [nTPM]":"1.8","Brain RNA - medulla oblongata [nTPM]":"2.4","Brain RNA - midbrain [nTPM]":"1.9","Brain RNA - pons [nTPM]":"2.4","Brain RNA - spinal cord [nTPM]":"1.8","Brain RNA - thalamus [nTPM]":"2.8","Brain RNA - white matter [nTPM]":"3.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"2.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"1.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.6","Single Cell Type RNA - Early spermatids [nTPM]":"55.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"4.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"4.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.4","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.1","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"29.4","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"2.3","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"9.8","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.5","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.9","Single Cell Type RNA - Spermatocytes [nTPM]":"46.7","Single Cell Type RNA - Spermatogonia [nTPM]":"10.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.1","Single Cell Type RNA - T-cells [nTPM]":"1.4","Single Cell Type RNA - Theca cells [nTPM]":"3.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"LMAN1","Gene synonym":["ERGIC-53","ERGIC53","F5F8D","FMFD1","gp58","MCFD1","MR60"],"Ensembl":"ENSG00000074695","Gene description":"Lectin, mannose binding 1","Uniprot":["P49257"],"Chromosome":"18","Position":"59327823-59359265","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["ER-Golgi transport","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"502.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002320","CAB037163"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"18000000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"CAB037163":"AB_532237","HPA002320":"AB_1079256"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-3"},"Tissue RNA - adipose tissue [nTPM]":"36.0","Tissue RNA - adrenal gland [nTPM]":"43.3","Tissue RNA - amygdala [nTPM]":"14.8","Tissue RNA - appendix [nTPM]":"39.4","Tissue RNA - basal ganglia [nTPM]":"16.4","Tissue RNA - bone marrow [nTPM]":"21.7","Tissue RNA - breast [nTPM]":"43.8","Tissue RNA - cerebellum [nTPM]":"16.9","Tissue RNA - cerebral cortex [nTPM]":"19.4","Tissue RNA - cervix [nTPM]":"66.0","Tissue RNA - choroid plexus [nTPM]":"20.1","Tissue RNA - colon [nTPM]":"34.1","Tissue RNA - duodenum [nTPM]":"45.7","Tissue RNA - endometrium 1 [nTPM]":"46.1","Tissue RNA - epididymis [nTPM]":"52.9","Tissue RNA - esophagus [nTPM]":"31.1","Tissue RNA - fallopian tube [nTPM]":"48.8","Tissue RNA - gallbladder [nTPM]":"31.9","Tissue RNA - heart muscle [nTPM]":"42.6","Tissue RNA - hippocampal formation [nTPM]":"13.8","Tissue RNA - hypothalamus [nTPM]":"19.4","Tissue RNA - kidney [nTPM]":"64.5","Tissue RNA - liver [nTPM]":"181.1","Tissue RNA - lung [nTPM]":"33.6","Tissue RNA - lymph node [nTPM]":"28.4","Tissue RNA - medulla oblongata [nTPM]":"17.1","Tissue RNA - midbrain [nTPM]":"16.0","Tissue RNA - ovary [nTPM]":"43.3","Tissue RNA - pancreas [nTPM]":"53.1","Tissue RNA - parathyroid gland [nTPM]":"74.3","Tissue RNA - pituitary gland [nTPM]":"32.7","Tissue RNA - placenta [nTPM]":"54.8","Tissue RNA - pons [nTPM]":"17.4","Tissue RNA - prostate [nTPM]":"58.4","Tissue RNA - rectum [nTPM]":"39.3","Tissue RNA - retina [nTPM]":"40.0","Tissue RNA - salivary gland [nTPM]":"69.0","Tissue RNA - seminal vesicle [nTPM]":"43.7","Tissue RNA - skeletal muscle [nTPM]":"33.3","Tissue RNA - skin 1 [nTPM]":"20.3","Tissue RNA - small intestine [nTPM]":"49.1","Tissue RNA - smooth muscle [nTPM]":"37.7","Tissue RNA - spinal cord [nTPM]":"16.2","Tissue RNA - spleen [nTPM]":"27.4","Tissue RNA - stomach 1 [nTPM]":"59.3","Tissue RNA - testis [nTPM]":"21.2","Tissue RNA - thalamus [nTPM]":"16.0","Tissue RNA - thymus [nTPM]":"32.1","Tissue RNA - thyroid gland [nTPM]":"86.5","Tissue RNA - tongue [nTPM]":"41.1","Tissue RNA - tonsil [nTPM]":"34.8","Tissue RNA - urinary bladder [nTPM]":"40.1","Tissue RNA - vagina [nTPM]":"21.2","Tissue RNA - white matter [nTPM]":"20.4","Cell RNA - A-431 [nTPM]":"90.6","Cell RNA - A549 [nTPM]":"52.7","Cell RNA - AF22 [nTPM]":"55.1","Cell RNA - AN3-CA [nTPM]":"46.4","Cell RNA - ASC diff [nTPM]":"125.6","Cell RNA - ASC TERT1 [nTPM]":"215.6","Cell RNA - BEWO [nTPM]":"110.7","Cell RNA - BJ [nTPM]":"159.6","Cell RNA - BJ hTERT+ [nTPM]":"227.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"105.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"140.5","Cell RNA - CACO-2 [nTPM]":"52.7","Cell RNA - CAPAN-2 [nTPM]":"85.2","Cell RNA - Daudi [nTPM]":"16.0","Cell RNA - EFO-21 [nTPM]":"110.7","Cell RNA - fHDF\/TERT166 [nTPM]":"191.0","Cell RNA - GAMG [nTPM]":"75.7","Cell RNA - HaCaT [nTPM]":"108.1","Cell RNA - HAP1 [nTPM]":"79.0","Cell RNA - HBEC3-KT [nTPM]":"90.5","Cell RNA - HBF TERT88 [nTPM]":"191.0","Cell RNA - HDLM-2 [nTPM]":"61.7","Cell RNA - HEK 293 [nTPM]":"50.4","Cell RNA - HEL [nTPM]":"52.5","Cell RNA - HeLa [nTPM]":"65.4","Cell RNA - Hep G2 [nTPM]":"109.5","Cell RNA - HHSteC [nTPM]":"148.9","Cell RNA - HL-60 [nTPM]":"183.6","Cell RNA - HMC-1 [nTPM]":"77.0","Cell RNA - HSkMC [nTPM]":"144.7","Cell RNA - hTCEpi [nTPM]":"106.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"102.5","Cell RNA - hTERT-HME1 [nTPM]":"208.1","Cell RNA - hTERT-RPE1 [nTPM]":"198.1","Cell RNA - HUVEC TERT2 [nTPM]":"108.1","Cell RNA - JURKAT [nTPM]":"54.3","Cell RNA - K-562 [nTPM]":"89.7","Cell RNA - Karpas-707 [nTPM]":"173.6","Cell RNA - LHCN-M2 [nTPM]":"104.2","Cell RNA - MCF7 [nTPM]":"24.5","Cell RNA - MOLT-4 [nTPM]":"53.5","Cell RNA - NB-4 [nTPM]":"37.9","Cell RNA - NTERA-2 [nTPM]":"37.8","Cell RNA - OE19 [nTPM]":"45.8","Cell RNA - PC-3 [nTPM]":"64.5","Cell RNA - REH [nTPM]":"60.0","Cell RNA - RH-30 [nTPM]":"100.1","Cell RNA - RPMI-8226 [nTPM]":"176.0","Cell RNA - RPTEC TERT1 [nTPM]":"58.9","Cell RNA - RT4 [nTPM]":"67.6","Cell RNA - SCLC-21H [nTPM]":"37.5","Cell RNA - SH-SY5Y [nTPM]":"40.9","Cell RNA - SiHa [nTPM]":"80.6","Cell RNA - SK-BR-3 [nTPM]":"78.0","Cell RNA - SK-MEL-30 [nTPM]":"91.6","Cell RNA - SuSa [nTPM]":"76.8","Cell RNA - T-47d [nTPM]":"57.8","Cell RNA - THP-1 [nTPM]":"70.8","Cell RNA - TIME [nTPM]":"89.8","Cell RNA - U-138 MG [nTPM]":"170.5","Cell RNA - U-2 OS [nTPM]":"59.9","Cell RNA - U-2197 [nTPM]":"55.2","Cell RNA - U-251 MG [nTPM]":"94.0","Cell RNA - U-266\/70 [nTPM]":"131.6","Cell RNA - U-266\/84 [nTPM]":"71.3","Cell RNA - U-698 [nTPM]":"76.2","Cell RNA - U-87 MG [nTPM]":"179.1","Cell RNA - U-937 [nTPM]":"96.0","Cell RNA - WM-115 [nTPM]":"142.6","Blood RNA - basophil [nTPM]":"6.0","Blood RNA - classical monocyte [nTPM]":"2.5","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"7.3","Blood RNA - intermediate monocyte [nTPM]":"3.7","Blood RNA - MAIT T-cell [nTPM]":"10.0","Blood RNA - memory B-cell [nTPM]":"7.1","Blood RNA - memory CD4 T-cell [nTPM]":"7.9","Blood RNA - memory CD8 T-cell [nTPM]":"7.7","Blood RNA - myeloid DC [nTPM]":"3.5","Blood RNA - naive B-cell [nTPM]":"5.1","Blood RNA - naive CD4 T-cell [nTPM]":"7.5","Blood RNA - naive CD8 T-cell [nTPM]":"7.7","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"10.0","Blood RNA - non-classical monocyte [nTPM]":"2.1","Blood RNA - plasmacytoid DC [nTPM]":"8.8","Blood RNA - T-reg [nTPM]":"9.6","Blood RNA - total PBMC [nTPM]":"4.0","Brain RNA - amygdala [nTPM]":"14.8","Brain RNA - basal ganglia [nTPM]":"16.4","Brain RNA - cerebellum [nTPM]":"16.9","Brain RNA - cerebral cortex [nTPM]":"19.4","Brain RNA - hippocampal formation [nTPM]":"13.8","Brain RNA - hypothalamus [nTPM]":"19.4","Brain RNA - medulla oblongata [nTPM]":"17.1","Brain RNA - midbrain [nTPM]":"16.0","Brain RNA - pons [nTPM]":"17.4","Brain RNA - spinal cord [nTPM]":"16.2","Brain RNA - thalamus [nTPM]":"16.0","Brain RNA - white matter [nTPM]":"20.4","Single Cell Type RNA - Adipocytes [nTPM]":"120.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"102.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"97.1","Single Cell Type RNA - Astrocytes [nTPM]":"15.0","Single Cell Type RNA - B-cells [nTPM]":"104.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"69.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"120.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"213.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"84.8","Single Cell Type RNA - Bipolar cells [nTPM]":"39.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"104.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"97.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"134.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"71.4","Single Cell Type RNA - Club cells [nTPM]":"171.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"80.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"106.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"149.3","Single Cell Type RNA - dendritic cells [nTPM]":"86.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"32.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"130.6","Single Cell Type RNA - Early spermatids [nTPM]":"28.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"117.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"203.7","Single Cell Type RNA - Endothelial cells [nTPM]":"97.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"51.6","Single Cell Type RNA - Erythroid cells [nTPM]":"49.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"84.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"304.8","Single Cell Type RNA - Fibroblasts [nTPM]":"162.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"106.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"200.7","Single Cell Type RNA - granulocytes [nTPM]":"33.6","Single Cell Type RNA - Granulosa cells [nTPM]":"96.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"75.0","Single Cell Type RNA - Hepatocytes [nTPM]":"394.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"80.2","Single Cell Type RNA - Horizontal cells [nTPM]":"58.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"181.4","Single Cell Type RNA - Ionocytes [nTPM]":"107.8","Single Cell Type RNA - Kupffer cells [nTPM]":"41.9","Single Cell Type RNA - Langerhans cells [nTPM]":"40.1","Single Cell Type RNA - Late spermatids [nTPM]":"10.3","Single Cell Type RNA - Leydig cells [nTPM]":"110.6","Single Cell Type RNA - Macrophages [nTPM]":"52.5","Single Cell Type RNA - Melanocytes [nTPM]":"67.6","Single Cell Type RNA - Microglial cells [nTPM]":"22.5","Single Cell Type RNA - monocytes [nTPM]":"53.5","Single Cell Type RNA - Muller glia cells [nTPM]":"76.8","Single Cell Type RNA - NK-cells [nTPM]":"54.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"33.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"71.6","Single Cell Type RNA - Paneth cells [nTPM]":"45.5","Single Cell Type RNA - Peritubular cells [nTPM]":"85.4","Single Cell Type RNA - Plasma cells [nTPM]":"502.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"214.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"95.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"75.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"164.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"66.7","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"95.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"142.3","Single Cell Type RNA - Spermatocytes [nTPM]":"47.2","Single Cell Type RNA - Spermatogonia [nTPM]":"65.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"80.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"57.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"231.2","Single Cell Type RNA - T-cells [nTPM]":"69.5","Single Cell Type RNA - Theca cells [nTPM]":"149.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"89.7","Single Cell Type RNA - Urothelial cells [nTPM]":"129.5"},{"Gene":"LMBRD1","Gene synonym":["bA810I22.1","C6orf209","cblF","FLJ11240"],"Ensembl":"ENSG00000168216","Gene description":"LMBR1 domain containing 1","Uniprot":["Q9NUN5"],"Chromosome":"6","Position":"69672757-69867236","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Endocytosis","Gastrulation","Host-virus interaction","Transport"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"21.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RPMI-8226":"37.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016491","HPA019547"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA016491":null,"HPA019547":"AB_2281256"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.07e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Tissue RNA - adipose tissue [nTPM]":"33.3","Tissue RNA - adrenal gland [nTPM]":"49.4","Tissue RNA - amygdala [nTPM]":"10.3","Tissue RNA - appendix [nTPM]":"11.5","Tissue RNA - basal ganglia [nTPM]":"10.8","Tissue RNA - bone marrow [nTPM]":"4.2","Tissue RNA - breast [nTPM]":"31.4","Tissue RNA - cerebellum [nTPM]":"20.7","Tissue RNA - cerebral cortex [nTPM]":"17.0","Tissue RNA - cervix [nTPM]":"28.9","Tissue RNA - choroid plexus [nTPM]":"13.3","Tissue RNA - colon [nTPM]":"26.4","Tissue RNA - duodenum [nTPM]":"13.5","Tissue RNA - endometrium 1 [nTPM]":"22.5","Tissue RNA - epididymis [nTPM]":"27.7","Tissue RNA - esophagus [nTPM]":"25.7","Tissue RNA - fallopian tube [nTPM]":"26.3","Tissue RNA - gallbladder [nTPM]":"16.0","Tissue RNA - heart muscle [nTPM]":"27.7","Tissue RNA - hippocampal formation [nTPM]":"11.1","Tissue RNA - hypothalamus [nTPM]":"11.5","Tissue RNA - kidney [nTPM]":"53.0","Tissue RNA - liver [nTPM]":"42.9","Tissue RNA - lung [nTPM]":"27.9","Tissue RNA - lymph node [nTPM]":"12.1","Tissue RNA - medulla oblongata [nTPM]":"13.6","Tissue RNA - midbrain [nTPM]":"11.9","Tissue RNA - ovary [nTPM]":"34.5","Tissue RNA - pancreas [nTPM]":"36.5","Tissue RNA - parathyroid gland [nTPM]":"31.7","Tissue RNA - pituitary gland [nTPM]":"26.5","Tissue RNA - placenta [nTPM]":"17.2","Tissue RNA - pons [nTPM]":"12.3","Tissue RNA - prostate [nTPM]":"19.1","Tissue RNA - rectum [nTPM]":"20.5","Tissue RNA - retina [nTPM]":"10.7","Tissue RNA - salivary gland [nTPM]":"33.2","Tissue RNA - seminal vesicle [nTPM]":"20.0","Tissue RNA - skeletal muscle [nTPM]":"28.8","Tissue RNA - skin 1 [nTPM]":"28.1","Tissue RNA - small intestine [nTPM]":"28.6","Tissue RNA - smooth muscle [nTPM]":"12.7","Tissue RNA - spinal cord [nTPM]":"11.4","Tissue RNA - spleen [nTPM]":"21.8","Tissue RNA - stomach 1 [nTPM]":"29.6","Tissue RNA - testis [nTPM]":"10.4","Tissue RNA - thalamus [nTPM]":"10.2","Tissue RNA - thymus [nTPM]":"9.1","Tissue RNA - thyroid gland [nTPM]":"35.1","Tissue RNA - tongue [nTPM]":"13.1","Tissue RNA - tonsil [nTPM]":"16.8","Tissue RNA - urinary bladder [nTPM]":"30.1","Tissue RNA - vagina [nTPM]":"29.4","Tissue RNA - white matter [nTPM]":"16.1","Cell RNA - A-431 [nTPM]":"3.8","Cell RNA - A549 [nTPM]":"3.8","Cell RNA - AF22 [nTPM]":"6.0","Cell RNA - AN3-CA [nTPM]":"10.2","Cell RNA - ASC diff [nTPM]":"16.5","Cell RNA - ASC TERT1 [nTPM]":"23.7","Cell RNA - BEWO [nTPM]":"17.9","Cell RNA - BJ [nTPM]":"2.2","Cell RNA - BJ hTERT+ [nTPM]":"7.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.6","Cell RNA - CACO-2 [nTPM]":"4.8","Cell RNA - CAPAN-2 [nTPM]":"8.2","Cell RNA - Daudi [nTPM]":"6.5","Cell RNA - EFO-21 [nTPM]":"9.2","Cell RNA - fHDF\/TERT166 [nTPM]":"8.8","Cell RNA - GAMG [nTPM]":"5.8","Cell RNA - HaCaT [nTPM]":"7.5","Cell RNA - HAP1 [nTPM]":"3.8","Cell RNA - HBEC3-KT [nTPM]":"9.8","Cell RNA - HBF TERT88 [nTPM]":"2.4","Cell RNA - HDLM-2 [nTPM]":"16.3","Cell RNA - HEK 293 [nTPM]":"11.9","Cell RNA - HEL [nTPM]":"6.2","Cell RNA - HeLa [nTPM]":"4.9","Cell RNA - Hep G2 [nTPM]":"7.8","Cell RNA - HHSteC [nTPM]":"13.7","Cell RNA - HL-60 [nTPM]":"3.4","Cell RNA - HMC-1 [nTPM]":"8.7","Cell RNA - HSkMC [nTPM]":"7.6","Cell RNA - hTCEpi [nTPM]":"9.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.8","Cell RNA - hTERT-HME1 [nTPM]":"5.7","Cell RNA - hTERT-RPE1 [nTPM]":"19.1","Cell RNA - HUVEC TERT2 [nTPM]":"7.4","Cell RNA - JURKAT [nTPM]":"5.5","Cell RNA - K-562 [nTPM]":"9.4","Cell RNA - Karpas-707 [nTPM]":"6.1","Cell RNA - LHCN-M2 [nTPM]":"6.0","Cell RNA - MCF7 [nTPM]":"8.1","Cell RNA - MOLT-4 [nTPM]":"2.5","Cell RNA - NB-4 [nTPM]":"4.7","Cell RNA - NTERA-2 [nTPM]":"4.6","Cell RNA - OE19 [nTPM]":"8.5","Cell RNA - PC-3 [nTPM]":"4.8","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"15.4","Cell RNA - RPMI-8226 [nTPM]":"37.8","Cell RNA - RPTEC TERT1 [nTPM]":"17.0","Cell RNA - RT4 [nTPM]":"13.8","Cell RNA - SCLC-21H [nTPM]":"5.5","Cell RNA - SH-SY5Y [nTPM]":"8.5","Cell RNA - SiHa [nTPM]":"0.9","Cell RNA - SK-BR-3 [nTPM]":"7.0","Cell RNA - SK-MEL-30 [nTPM]":"13.3","Cell RNA - SuSa [nTPM]":"3.0","Cell RNA - T-47d [nTPM]":"4.6","Cell RNA - THP-1 [nTPM]":"25.3","Cell RNA - TIME [nTPM]":"1.1","Cell RNA - U-138 MG [nTPM]":"3.9","Cell RNA - U-2 OS [nTPM]":"4.6","Cell RNA - U-2197 [nTPM]":"4.3","Cell RNA - U-251 MG [nTPM]":"2.8","Cell RNA - U-266\/70 [nTPM]":"8.8","Cell RNA - U-266\/84 [nTPM]":"5.5","Cell RNA - U-698 [nTPM]":"2.8","Cell RNA - U-87 MG [nTPM]":"2.3","Cell RNA - U-937 [nTPM]":"4.0","Cell RNA - WM-115 [nTPM]":"12.3","Blood RNA - basophil [nTPM]":"6.5","Blood RNA - classical monocyte [nTPM]":"2.2","Blood RNA - eosinophil [nTPM]":"3.9","Blood RNA - gdT-cell [nTPM]":"2.0","Blood RNA - intermediate monocyte [nTPM]":"2.5","Blood RNA - MAIT T-cell [nTPM]":"2.5","Blood RNA - memory B-cell [nTPM]":"12.1","Blood RNA - memory CD4 T-cell [nTPM]":"2.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.9","Blood RNA - myeloid DC [nTPM]":"1.7","Blood RNA - naive B-cell [nTPM]":"21.0","Blood RNA - naive CD4 T-cell [nTPM]":"3.1","Blood RNA - naive CD8 T-cell [nTPM]":"2.3","Blood RNA - neutrophil [nTPM]":"11.4","Blood RNA - NK-cell [nTPM]":"2.6","Blood RNA - non-classical monocyte [nTPM]":"4.8","Blood RNA - plasmacytoid DC [nTPM]":"2.2","Blood RNA - T-reg [nTPM]":"3.7","Blood RNA - total PBMC [nTPM]":"2.1","Brain RNA - amygdala [nTPM]":"10.3","Brain RNA - basal ganglia [nTPM]":"10.8","Brain RNA - cerebellum [nTPM]":"20.7","Brain RNA - cerebral cortex [nTPM]":"17.0","Brain RNA - hippocampal formation [nTPM]":"11.1","Brain RNA - hypothalamus [nTPM]":"11.5","Brain RNA - medulla oblongata [nTPM]":"13.6","Brain RNA - midbrain [nTPM]":"11.9","Brain RNA - pons [nTPM]":"12.3","Brain RNA - spinal cord [nTPM]":"11.4","Brain RNA - thalamus [nTPM]":"10.2","Brain RNA - white matter [nTPM]":"16.1","Single Cell Type RNA - Adipocytes [nTPM]":"49.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"64.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"38.3","Single Cell Type RNA - Astrocytes [nTPM]":"82.3","Single Cell Type RNA - B-cells [nTPM]":"93.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"29.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"41.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"45.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"71.2","Single Cell Type RNA - Bipolar cells [nTPM]":"73.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"39.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"25.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"40.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"50.1","Single Cell Type RNA - Club cells [nTPM]":"56.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"58.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"110.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"69.6","Single Cell Type RNA - dendritic cells [nTPM]":"36.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"79.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"49.0","Single Cell Type RNA - Early spermatids [nTPM]":"28.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"48.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.7","Single Cell Type RNA - Endothelial cells [nTPM]":"41.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.7","Single Cell Type RNA - Erythroid cells [nTPM]":"18.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"119.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"49.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"59.2","Single Cell Type RNA - Fibroblasts [nTPM]":"56.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"36.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"61.7","Single Cell Type RNA - granulocytes [nTPM]":"40.5","Single Cell Type RNA - Granulosa cells [nTPM]":"15.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"44.6","Single Cell Type RNA - Hepatocytes [nTPM]":"60.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"42.1","Single Cell Type RNA - Horizontal cells [nTPM]":"55.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"144.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"37.6","Single Cell Type RNA - Ionocytes [nTPM]":"44.7","Single Cell Type RNA - Kupffer cells [nTPM]":"66.9","Single Cell Type RNA - Langerhans cells [nTPM]":"36.3","Single Cell Type RNA - Late spermatids [nTPM]":"9.3","Single Cell Type RNA - Leydig cells [nTPM]":"35.4","Single Cell Type RNA - Macrophages [nTPM]":"52.0","Single Cell Type RNA - Melanocytes [nTPM]":"32.0","Single Cell Type RNA - Microglial cells [nTPM]":"79.6","Single Cell Type RNA - monocytes [nTPM]":"49.3","Single Cell Type RNA - Muller glia cells [nTPM]":"56.3","Single Cell Type RNA - NK-cells [nTPM]":"28.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"122.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"156.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"42.0","Single Cell Type RNA - Paneth cells [nTPM]":"51.0","Single Cell Type RNA - Peritubular cells [nTPM]":"33.8","Single Cell Type RNA - Plasma cells [nTPM]":"82.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"78.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"64.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"65.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"90.8","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"36.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"33.9","Single Cell Type RNA - Spermatocytes [nTPM]":"22.5","Single Cell Type RNA - Spermatogonia [nTPM]":"16.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"43.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"38.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"77.4","Single Cell Type RNA - T-cells [nTPM]":"43.2","Single Cell Type RNA - Theca cells [nTPM]":"26.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"31.7","Single Cell Type RNA - Urothelial cells [nTPM]":"34.2"},{"Gene":"LNPK","Gene synonym":["KIAA1715","LNP","LNP1","Ul"],"Ensembl":"ENSG00000144320","Gene description":"Lunapark, ER junction formation factor","Uniprot":["Q9C0E8"],"Chromosome":"2","Position":"175923882-176002839","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"19.3","Endometrial stromal cells":"24.6","Hofbauer cells":"24.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-138 MG":"159.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014205"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"15000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA014205":"AB_2234186"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Tissue RNA - adipose tissue [nTPM]":"13.5","Tissue RNA - adrenal gland [nTPM]":"8.9","Tissue RNA - amygdala [nTPM]":"6.3","Tissue RNA - appendix [nTPM]":"7.7","Tissue RNA - basal ganglia [nTPM]":"10.1","Tissue RNA - bone marrow [nTPM]":"30.1","Tissue RNA - breast [nTPM]":"9.8","Tissue RNA - cerebellum [nTPM]":"10.2","Tissue RNA - cerebral cortex [nTPM]":"8.7","Tissue RNA - cervix [nTPM]":"12.0","Tissue RNA - choroid plexus [nTPM]":"4.2","Tissue RNA - colon [nTPM]":"12.0","Tissue RNA - duodenum [nTPM]":"7.6","Tissue RNA - endometrium 1 [nTPM]":"8.6","Tissue RNA - epididymis [nTPM]":"6.2","Tissue RNA - esophagus [nTPM]":"13.1","Tissue RNA - fallopian tube [nTPM]":"6.3","Tissue RNA - gallbladder [nTPM]":"7.7","Tissue RNA - heart muscle [nTPM]":"12.2","Tissue RNA - hippocampal formation [nTPM]":"7.6","Tissue RNA - hypothalamus [nTPM]":"13.2","Tissue RNA - kidney [nTPM]":"8.2","Tissue RNA - liver [nTPM]":"14.4","Tissue RNA - lung [nTPM]":"6.7","Tissue RNA - lymph node [nTPM]":"7.2","Tissue RNA - medulla oblongata [nTPM]":"11.3","Tissue RNA - midbrain [nTPM]":"9.2","Tissue RNA - ovary [nTPM]":"10.7","Tissue RNA - pancreas [nTPM]":"5.5","Tissue RNA - parathyroid gland [nTPM]":"15.6","Tissue RNA - pituitary gland [nTPM]":"6.0","Tissue RNA - placenta [nTPM]":"6.1","Tissue RNA - pons [nTPM]":"14.1","Tissue RNA - prostate [nTPM]":"10.1","Tissue RNA - rectum [nTPM]":"10.2","Tissue RNA - retina [nTPM]":"24.1","Tissue RNA - salivary gland [nTPM]":"6.4","Tissue RNA - seminal vesicle [nTPM]":"8.2","Tissue RNA - skeletal muscle [nTPM]":"34.1","Tissue RNA - skin 1 [nTPM]":"12.1","Tissue RNA - small intestine [nTPM]":"7.5","Tissue RNA - smooth muscle [nTPM]":"9.6","Tissue RNA - spinal cord [nTPM]":"11.3","Tissue RNA - spleen [nTPM]":"5.9","Tissue RNA - stomach 1 [nTPM]":"7.8","Tissue RNA - testis [nTPM]":"24.5","Tissue RNA - thalamus [nTPM]":"9.3","Tissue RNA - thymus [nTPM]":"14.0","Tissue RNA - thyroid gland [nTPM]":"8.8","Tissue RNA - tongue [nTPM]":"26.8","Tissue RNA - tonsil [nTPM]":"7.9","Tissue RNA - urinary bladder [nTPM]":"7.6","Tissue RNA - vagina [nTPM]":"9.2","Tissue RNA - white matter [nTPM]":"19.0","Cell RNA - A-431 [nTPM]":"24.5","Cell RNA - A549 [nTPM]":"12.3","Cell RNA - AF22 [nTPM]":"28.3","Cell RNA - AN3-CA [nTPM]":"40.1","Cell RNA - ASC diff [nTPM]":"58.5","Cell RNA - ASC TERT1 [nTPM]":"36.1","Cell RNA - BEWO [nTPM]":"14.3","Cell RNA - BJ [nTPM]":"70.8","Cell RNA - BJ hTERT+ [nTPM]":"33.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"32.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"45.1","Cell RNA - CACO-2 [nTPM]":"17.0","Cell RNA - CAPAN-2 [nTPM]":"28.2","Cell RNA - Daudi [nTPM]":"24.4","Cell RNA - EFO-21 [nTPM]":"39.4","Cell RNA - fHDF\/TERT166 [nTPM]":"31.5","Cell RNA - GAMG [nTPM]":"42.3","Cell RNA - HaCaT [nTPM]":"26.5","Cell RNA - HAP1 [nTPM]":"26.9","Cell RNA - HBEC3-KT [nTPM]":"18.9","Cell RNA - HBF TERT88 [nTPM]":"44.6","Cell RNA - HDLM-2 [nTPM]":"37.5","Cell RNA - HEK 293 [nTPM]":"27.4","Cell RNA - HEL [nTPM]":"27.6","Cell RNA - HeLa [nTPM]":"14.8","Cell RNA - Hep G2 [nTPM]":"15.2","Cell RNA - HHSteC [nTPM]":"13.8","Cell RNA - HL-60 [nTPM]":"47.2","Cell RNA - HMC-1 [nTPM]":"32.9","Cell RNA - HSkMC [nTPM]":"29.9","Cell RNA - hTCEpi [nTPM]":"17.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"31.4","Cell RNA - hTERT-HME1 [nTPM]":"15.4","Cell RNA - hTERT-RPE1 [nTPM]":"26.4","Cell RNA - HUVEC TERT2 [nTPM]":"6.0","Cell RNA - JURKAT [nTPM]":"19.3","Cell RNA - K-562 [nTPM]":"28.9","Cell RNA - Karpas-707 [nTPM]":"31.5","Cell RNA - LHCN-M2 [nTPM]":"44.9","Cell RNA - MCF7 [nTPM]":"16.0","Cell RNA - MOLT-4 [nTPM]":"31.4","Cell RNA - NB-4 [nTPM]":"18.8","Cell RNA - NTERA-2 [nTPM]":"9.2","Cell RNA - OE19 [nTPM]":"24.9","Cell RNA - PC-3 [nTPM]":"23.4","Cell RNA - REH [nTPM]":"31.3","Cell RNA - RH-30 [nTPM]":"28.6","Cell RNA - RPMI-8226 [nTPM]":"18.0","Cell RNA - RPTEC TERT1 [nTPM]":"13.6","Cell RNA - RT4 [nTPM]":"22.2","Cell RNA - SCLC-21H [nTPM]":"32.6","Cell RNA - SH-SY5Y [nTPM]":"32.9","Cell RNA - SiHa [nTPM]":"31.3","Cell RNA - SK-BR-3 [nTPM]":"17.5","Cell RNA - SK-MEL-30 [nTPM]":"24.1","Cell RNA - SuSa [nTPM]":"26.6","Cell RNA - T-47d [nTPM]":"26.2","Cell RNA - THP-1 [nTPM]":"15.4","Cell RNA - TIME [nTPM]":"9.2","Cell RNA - U-138 MG [nTPM]":"159.0","Cell RNA - U-2 OS [nTPM]":"23.6","Cell RNA - U-2197 [nTPM]":"53.9","Cell RNA - U-251 MG [nTPM]":"33.7","Cell RNA - U-266\/70 [nTPM]":"18.5","Cell RNA - U-266\/84 [nTPM]":"36.6","Cell RNA - U-698 [nTPM]":"20.3","Cell RNA - U-87 MG [nTPM]":"49.4","Cell RNA - U-937 [nTPM]":"15.2","Cell RNA - WM-115 [nTPM]":"30.4","Blood RNA - basophil [nTPM]":"3.7","Blood RNA - classical monocyte [nTPM]":"4.2","Blood RNA - eosinophil [nTPM]":"7.9","Blood RNA - gdT-cell [nTPM]":"4.9","Blood RNA - intermediate monocyte [nTPM]":"4.8","Blood RNA - MAIT T-cell [nTPM]":"5.8","Blood RNA - memory B-cell [nTPM]":"4.3","Blood RNA - memory CD4 T-cell [nTPM]":"4.2","Blood RNA - memory CD8 T-cell [nTPM]":"5.4","Blood RNA - myeloid DC [nTPM]":"3.9","Blood RNA - naive B-cell [nTPM]":"3.3","Blood RNA - naive CD4 T-cell [nTPM]":"4.2","Blood RNA - naive CD8 T-cell [nTPM]":"6.7","Blood RNA - neutrophil [nTPM]":"3.4","Blood RNA - NK-cell [nTPM]":"6.5","Blood RNA - non-classical monocyte [nTPM]":"4.5","Blood RNA - plasmacytoid DC [nTPM]":"4.4","Blood RNA - T-reg [nTPM]":"7.8","Blood RNA - total PBMC [nTPM]":"3.4","Brain RNA - amygdala [nTPM]":"6.3","Brain RNA - basal ganglia [nTPM]":"10.1","Brain RNA - cerebellum [nTPM]":"10.2","Brain RNA - cerebral cortex [nTPM]":"8.7","Brain RNA - hippocampal formation [nTPM]":"7.6","Brain RNA - hypothalamus [nTPM]":"13.2","Brain RNA - medulla oblongata [nTPM]":"11.3","Brain RNA - midbrain [nTPM]":"9.2","Brain RNA - pons [nTPM]":"14.1","Brain RNA - spinal cord [nTPM]":"11.3","Brain RNA - thalamus [nTPM]":"9.3","Brain RNA - white matter [nTPM]":"19.0","Single Cell Type RNA - Adipocytes [nTPM]":"10.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"4.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"6.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.7","Single Cell Type RNA - dendritic cells [nTPM]":"14.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"14.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"24.6","Single Cell Type RNA - Endothelial cells [nTPM]":"3.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.3","Single Cell Type RNA - Fibroblasts [nTPM]":"12.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.7","Single Cell Type RNA - granulocytes [nTPM]":"11.4","Single Cell Type RNA - Granulosa cells [nTPM]":"10.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"9.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"2.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"3.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.3","Single Cell Type RNA - T-cells [nTPM]":"7.2","Single Cell Type RNA - Theca cells [nTPM]":"12.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"LONP1","Gene synonym":["hLON","LonHS","PIM1","PRSS15"],"Ensembl":"ENSG00000196365","Gene description":"Lon peptidase 1, mitochondrial","Uniprot":["P36776"],"Chromosome":"19","Position":"5691834-5720572","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["DNA-binding","Hydrolase","Protease","Serine protease"],"Disease involvement":["Cataract","Deafness","Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"196.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Theca cells":"85.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002034","HPA002192"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7900","Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA002034":"AB_2756304","HPA002192":"AB_1079695"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Tissue RNA - adipose tissue [nTPM]":"30.4","Tissue RNA - adrenal gland [nTPM]":"196.2","Tissue RNA - amygdala [nTPM]":"31.5","Tissue RNA - appendix [nTPM]":"22.2","Tissue RNA - basal ganglia [nTPM]":"32.7","Tissue RNA - bone marrow [nTPM]":"23.7","Tissue RNA - breast [nTPM]":"27.2","Tissue RNA - cerebellum [nTPM]":"34.6","Tissue RNA - cerebral cortex [nTPM]":"42.8","Tissue RNA - cervix [nTPM]":"24.4","Tissue RNA - choroid plexus [nTPM]":"39.9","Tissue RNA - colon [nTPM]":"27.9","Tissue RNA - duodenum [nTPM]":"22.6","Tissue RNA - endometrium 1 [nTPM]":"25.2","Tissue RNA - epididymis [nTPM]":"14.1","Tissue RNA - esophagus [nTPM]":"27.7","Tissue RNA - fallopian tube [nTPM]":"22.6","Tissue RNA - gallbladder [nTPM]":"15.4","Tissue RNA - heart muscle [nTPM]":"76.0","Tissue RNA - hippocampal formation [nTPM]":"30.8","Tissue RNA - hypothalamus [nTPM]":"35.7","Tissue RNA - kidney [nTPM]":"43.2","Tissue RNA - liver [nTPM]":"79.1","Tissue RNA - lung [nTPM]":"25.6","Tissue RNA - lymph node [nTPM]":"24.1","Tissue RNA - medulla oblongata [nTPM]":"37.6","Tissue RNA - midbrain [nTPM]":"35.8","Tissue RNA - ovary [nTPM]":"26.6","Tissue RNA - pancreas [nTPM]":"38.2","Tissue RNA - parathyroid gland [nTPM]":"35.2","Tissue RNA - pituitary gland [nTPM]":"41.5","Tissue RNA - placenta [nTPM]":"18.5","Tissue RNA - pons [nTPM]":"37.9","Tissue RNA - prostate [nTPM]":"26.4","Tissue RNA - rectum [nTPM]":"13.2","Tissue RNA - retina [nTPM]":"13.0","Tissue RNA - salivary gland [nTPM]":"30.8","Tissue RNA - seminal vesicle [nTPM]":"16.6","Tissue RNA - skeletal muscle [nTPM]":"69.3","Tissue RNA - skin 1 [nTPM]":"28.9","Tissue RNA - small intestine [nTPM]":"25.5","Tissue RNA - smooth muscle [nTPM]":"14.7","Tissue RNA - spinal cord [nTPM]":"30.8","Tissue RNA - spleen [nTPM]":"29.5","Tissue RNA - stomach 1 [nTPM]":"33.7","Tissue RNA - testis [nTPM]":"24.2","Tissue RNA - thalamus [nTPM]":"37.2","Tissue RNA - thymus [nTPM]":"17.5","Tissue RNA - thyroid gland [nTPM]":"34.6","Tissue RNA - tongue [nTPM]":"40.7","Tissue RNA - tonsil [nTPM]":"14.5","Tissue RNA - urinary bladder [nTPM]":"28.2","Tissue RNA - vagina [nTPM]":"22.4","Tissue RNA - white matter [nTPM]":"33.0","Cell RNA - A-431 [nTPM]":"108.4","Cell RNA - A549 [nTPM]":"111.0","Cell RNA - AF22 [nTPM]":"35.6","Cell RNA - AN3-CA [nTPM]":"114.0","Cell RNA - ASC diff [nTPM]":"41.4","Cell RNA - ASC TERT1 [nTPM]":"29.2","Cell RNA - BEWO [nTPM]":"110.4","Cell RNA - BJ [nTPM]":"67.2","Cell RNA - BJ hTERT+ [nTPM]":"52.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"71.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"86.0","Cell RNA - CACO-2 [nTPM]":"96.3","Cell RNA - CAPAN-2 [nTPM]":"37.7","Cell RNA - Daudi [nTPM]":"134.3","Cell RNA - EFO-21 [nTPM]":"91.4","Cell RNA - fHDF\/TERT166 [nTPM]":"70.6","Cell RNA - GAMG [nTPM]":"68.0","Cell RNA - HaCaT [nTPM]":"45.0","Cell RNA - HAP1 [nTPM]":"92.1","Cell RNA - HBEC3-KT [nTPM]":"81.1","Cell RNA - HBF TERT88 [nTPM]":"34.2","Cell RNA - HDLM-2 [nTPM]":"80.0","Cell RNA - HEK 293 [nTPM]":"78.0","Cell RNA - HEL [nTPM]":"74.5","Cell RNA - HeLa [nTPM]":"97.5","Cell RNA - Hep G2 [nTPM]":"127.6","Cell RNA - HHSteC [nTPM]":"190.4","Cell RNA - HL-60 [nTPM]":"169.7","Cell RNA - HMC-1 [nTPM]":"74.9","Cell RNA - HSkMC [nTPM]":"55.0","Cell RNA - hTCEpi [nTPM]":"114.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"67.5","Cell RNA - hTERT-HME1 [nTPM]":"132.6","Cell RNA - hTERT-RPE1 [nTPM]":"34.1","Cell RNA - HUVEC TERT2 [nTPM]":"57.5","Cell RNA - JURKAT [nTPM]":"183.9","Cell RNA - K-562 [nTPM]":"200.9","Cell RNA - Karpas-707 [nTPM]":"259.4","Cell RNA - LHCN-M2 [nTPM]":"33.0","Cell RNA - MCF7 [nTPM]":"71.8","Cell RNA - MOLT-4 [nTPM]":"85.5","Cell RNA - NB-4 [nTPM]":"101.6","Cell RNA - NTERA-2 [nTPM]":"127.6","Cell RNA - OE19 [nTPM]":"43.6","Cell RNA - PC-3 [nTPM]":"143.1","Cell RNA - REH [nTPM]":"89.4","Cell RNA - RH-30 [nTPM]":"50.9","Cell RNA - RPMI-8226 [nTPM]":"146.6","Cell RNA - RPTEC TERT1 [nTPM]":"39.3","Cell RNA - RT4 [nTPM]":"63.9","Cell RNA - SCLC-21H [nTPM]":"94.2","Cell RNA - SH-SY5Y [nTPM]":"94.1","Cell RNA - SiHa [nTPM]":"59.4","Cell RNA - SK-BR-3 [nTPM]":"85.2","Cell RNA - SK-MEL-30 [nTPM]":"242.2","Cell RNA - SuSa [nTPM]":"24.9","Cell RNA - T-47d [nTPM]":"50.3","Cell RNA - THP-1 [nTPM]":"211.9","Cell RNA - TIME [nTPM]":"41.2","Cell RNA - U-138 MG [nTPM]":"36.0","Cell RNA - U-2 OS [nTPM]":"39.2","Cell RNA - U-2197 [nTPM]":"100.7","Cell RNA - U-251 MG [nTPM]":"99.2","Cell RNA - U-266\/70 [nTPM]":"272.3","Cell RNA - U-266\/84 [nTPM]":"182.6","Cell RNA - U-698 [nTPM]":"121.4","Cell RNA - U-87 MG [nTPM]":"161.7","Cell RNA - U-937 [nTPM]":"185.0","Cell RNA - WM-115 [nTPM]":"66.2","Blood RNA - basophil [nTPM]":"4.5","Blood RNA - classical monocyte [nTPM]":"2.4","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"3.4","Blood RNA - intermediate monocyte [nTPM]":"3.7","Blood RNA - MAIT T-cell [nTPM]":"2.3","Blood RNA - memory B-cell [nTPM]":"4.0","Blood RNA - memory CD4 T-cell [nTPM]":"3.1","Blood RNA - memory CD8 T-cell [nTPM]":"3.4","Blood RNA - myeloid DC [nTPM]":"2.6","Blood RNA - naive B-cell [nTPM]":"3.7","Blood RNA - naive CD4 T-cell [nTPM]":"3.8","Blood RNA - naive CD8 T-cell [nTPM]":"2.6","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"2.7","Blood RNA - non-classical monocyte [nTPM]":"1.5","Blood RNA - plasmacytoid DC [nTPM]":"3.9","Blood RNA - T-reg [nTPM]":"2.7","Blood RNA - total PBMC [nTPM]":"1.7","Brain RNA - amygdala [nTPM]":"31.5","Brain RNA - basal ganglia [nTPM]":"32.7","Brain RNA - cerebellum [nTPM]":"34.6","Brain RNA - cerebral cortex [nTPM]":"42.8","Brain RNA - hippocampal formation [nTPM]":"30.8","Brain RNA - hypothalamus [nTPM]":"35.7","Brain RNA - medulla oblongata [nTPM]":"37.6","Brain RNA - midbrain [nTPM]":"35.8","Brain RNA - pons [nTPM]":"37.9","Brain RNA - spinal cord [nTPM]":"30.8","Brain RNA - thalamus [nTPM]":"37.2","Brain RNA - white matter [nTPM]":"33.0","Single Cell Type RNA - Adipocytes [nTPM]":"12.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.1","Single Cell Type RNA - Astrocytes [nTPM]":"18.3","Single Cell Type RNA - B-cells [nTPM]":"14.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"26.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"14.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"28.8","Single Cell Type RNA - dendritic cells [nTPM]":"8.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"40.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"46.9","Single Cell Type RNA - Ductal cells [nTPM]":"33.9","Single Cell Type RNA - Early spermatids [nTPM]":"6.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"24.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.3","Single Cell Type RNA - Endothelial cells [nTPM]":"15.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.4","Single Cell Type RNA - Erythroid cells [nTPM]":"17.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"28.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"31.9","Single Cell Type RNA - Fibroblasts [nTPM]":"13.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"29.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.6","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"51.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.4","Single Cell Type RNA - Hepatocytes [nTPM]":"47.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.8","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.4","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"14.6","Single Cell Type RNA - Langerhans cells [nTPM]":"8.6","Single Cell Type RNA - Late spermatids [nTPM]":"6.3","Single Cell Type RNA - Leydig cells [nTPM]":"12.8","Single Cell Type RNA - Macrophages [nTPM]":"16.4","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"17.8","Single Cell Type RNA - Muller glia cells [nTPM]":"24.9","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"26.0","Single Cell Type RNA - Paneth cells [nTPM]":"16.8","Single Cell Type RNA - Peritubular cells [nTPM]":"17.3","Single Cell Type RNA - Plasma cells [nTPM]":"17.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"27.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"50.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"26.5","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"24.7","Single Cell Type RNA - Spermatocytes [nTPM]":"12.0","Single Cell Type RNA - Spermatogonia [nTPM]":"14.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"35.0","Single Cell Type RNA - T-cells [nTPM]":"10.7","Single Cell Type RNA - Theca cells [nTPM]":"85.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"35.1","Single Cell Type RNA - Urothelial cells [nTPM]":"11.4"},{"Gene":"LOX","Gene synonym":[],"Ensembl":"ENSG00000113083","Gene description":"Lysyl oxidase","Uniprot":["P28300"],"Chromosome":"5","Position":"122063195-122078413","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Aortic aneurysm","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"27.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"67.1","Club cells":"38.4","Early spermatids":"41.9","Endometrial stromal cells":"34.0","Extravillous trophoblasts":"44.2","Fibroblasts":"79.1","Peritubular cells":"39.1","Smooth muscle cells":"32.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"39.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ":"777.3","fHDF\/TERT166":"1790.7","HSkMC":"356.3","U-138 MG":"475.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043930"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"550000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA043930":"AB_2678736"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.38e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.93e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.32e-4"},"Tissue RNA - adipose tissue [nTPM]":"27.9","Tissue RNA - adrenal gland [nTPM]":"2.4","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"6.8","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"17.6","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"0.9","Tissue RNA - cervix [nTPM]":"10.8","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"4.2","Tissue RNA - duodenum [nTPM]":"3.8","Tissue RNA - endometrium 1 [nTPM]":"6.2","Tissue RNA - epididymis [nTPM]":"1.7","Tissue RNA - esophagus [nTPM]":"5.6","Tissue RNA - fallopian tube [nTPM]":"8.9","Tissue RNA - gallbladder [nTPM]":"18.8","Tissue RNA - heart muscle [nTPM]":"23.9","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.4","Tissue RNA - kidney [nTPM]":"4.5","Tissue RNA - liver [nTPM]":"2.1","Tissue RNA - lung [nTPM]":"13.6","Tissue RNA - lymph node [nTPM]":"3.3","Tissue RNA - medulla oblongata [nTPM]":"1.3","Tissue RNA - midbrain [nTPM]":"1.4","Tissue RNA - ovary [nTPM]":"5.4","Tissue RNA - pancreas [nTPM]":"3.3","Tissue RNA - parathyroid gland [nTPM]":"0.9","Tissue RNA - pituitary gland [nTPM]":"1.2","Tissue RNA - placenta [nTPM]":"8.1","Tissue RNA - pons [nTPM]":"0.8","Tissue RNA - prostate [nTPM]":"4.1","Tissue RNA - rectum [nTPM]":"4.5","Tissue RNA - retina [nTPM]":"1.1","Tissue RNA - salivary gland [nTPM]":"3.2","Tissue RNA - seminal vesicle [nTPM]":"2.6","Tissue RNA - skeletal muscle [nTPM]":"1.9","Tissue RNA - skin 1 [nTPM]":"12.4","Tissue RNA - small intestine [nTPM]":"3.7","Tissue RNA - smooth muscle [nTPM]":"10.0","Tissue RNA - spinal cord [nTPM]":"1.2","Tissue RNA - spleen [nTPM]":"2.6","Tissue RNA - stomach 1 [nTPM]":"4.4","Tissue RNA - testis [nTPM]":"1.4","Tissue RNA - thalamus [nTPM]":"0.5","Tissue RNA - thymus [nTPM]":"0.9","Tissue RNA - thyroid gland [nTPM]":"6.9","Tissue RNA - tongue [nTPM]":"2.1","Tissue RNA - tonsil [nTPM]":"1.4","Tissue RNA - urinary bladder [nTPM]":"14.1","Tissue RNA - vagina [nTPM]":"4.8","Tissue RNA - white matter [nTPM]":"1.0","Cell RNA - A-431 [nTPM]":"0.8","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"2.0","Cell RNA - AN3-CA [nTPM]":"0.9","Cell RNA - ASC diff [nTPM]":"168.7","Cell RNA - ASC TERT1 [nTPM]":"185.2","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"777.3","Cell RNA - BJ hTERT+ [nTPM]":"205.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"73.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"246.4","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"16.5","Cell RNA - fHDF\/TERT166 [nTPM]":"1790.7","Cell RNA - GAMG [nTPM]":"3.7","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"4.5","Cell RNA - HBEC3-KT [nTPM]":"3.5","Cell RNA - HBF TERT88 [nTPM]":"196.4","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"2.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"16.3","Cell RNA - Hep G2 [nTPM]":"9.3","Cell RNA - HHSteC [nTPM]":"203.4","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"356.3","Cell RNA - hTCEpi [nTPM]":"4.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"137.6","Cell RNA - hTERT-HME1 [nTPM]":"7.4","Cell RNA - hTERT-RPE1 [nTPM]":"329.3","Cell RNA - HUVEC TERT2 [nTPM]":"95.3","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"83.6","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"6.4","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"1.9","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"7.4","Cell RNA - RPMI-8226 [nTPM]":"0.9","Cell RNA - RPTEC TERT1 [nTPM]":"4.9","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"4.2","Cell RNA - SiHa [nTPM]":"72.1","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"12.9","Cell RNA - SuSa [nTPM]":"29.8","Cell RNA - T-47d [nTPM]":"0.6","Cell RNA - THP-1 [nTPM]":"0.6","Cell RNA - TIME [nTPM]":"6.8","Cell RNA - U-138 MG [nTPM]":"475.5","Cell RNA - U-2 OS [nTPM]":"23.2","Cell RNA - U-2197 [nTPM]":"272.8","Cell RNA - U-251 MG [nTPM]":"9.3","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"207.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"0.9","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.4","Brain RNA - medulla oblongata [nTPM]":"1.3","Brain RNA - midbrain [nTPM]":"1.4","Brain RNA - pons [nTPM]":"0.8","Brain RNA - spinal cord [nTPM]":"1.2","Brain RNA - thalamus [nTPM]":"0.5","Brain RNA - white matter [nTPM]":"1.0","Single Cell Type RNA - Adipocytes [nTPM]":"20.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"67.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"38.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"7.2","Single Cell Type RNA - Early spermatids [nTPM]":"41.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"34.0","Single Cell Type RNA - Endothelial cells [nTPM]":"9.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"44.2","Single Cell Type RNA - Fibroblasts [nTPM]":"79.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.2","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"21.6","Single Cell Type RNA - Late spermatids [nTPM]":"5.0","Single Cell Type RNA - Leydig cells [nTPM]":"14.0","Single Cell Type RNA - Macrophages [nTPM]":"1.3","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"39.1","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.7","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.8","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.9"},{"Gene":"LOXL3","Gene synonym":[],"Ensembl":"ENSG00000115318","Gene description":"Lysyl oxidase like 3","Uniprot":["P58215"],"Chromosome":"2","Position":"74532258-74555690","Protein class":["Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Inflammatory response"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Deafness","Stickler syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"14.0","Hofbauer cells":"17.9","Kupffer cells":"12.5","Macrophages":"12.3","Microglial cells":"30.0","Muller glia cells":"10.6","Oligodendrocyte precursor cells":"11.6","Sertoli cells":"19.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"15.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"11.7","non-classical monocyte":"9.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+":"143.4","HDLM-2":"110.7","U-138 MG":"245.9","WM-115":"549.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035281"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"200000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035281":"AB_10601766"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.97e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.33e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.8","Tissue RNA - adrenal gland [nTPM]":"5.3","Tissue RNA - amygdala [nTPM]":"4.5","Tissue RNA - appendix [nTPM]":"7.8","Tissue RNA - basal ganglia [nTPM]":"4.7","Tissue RNA - bone marrow [nTPM]":"14.3","Tissue RNA - breast [nTPM]":"3.0","Tissue RNA - cerebellum [nTPM]":"4.5","Tissue RNA - cerebral cortex [nTPM]":"5.3","Tissue RNA - cervix [nTPM]":"5.1","Tissue RNA - choroid plexus [nTPM]":"3.8","Tissue RNA - colon [nTPM]":"7.3","Tissue RNA - duodenum [nTPM]":"4.0","Tissue RNA - endometrium 1 [nTPM]":"7.4","Tissue RNA - epididymis [nTPM]":"1.7","Tissue RNA - esophagus [nTPM]":"3.2","Tissue RNA - fallopian tube [nTPM]":"4.9","Tissue RNA - gallbladder [nTPM]":"6.5","Tissue RNA - heart muscle [nTPM]":"8.2","Tissue RNA - hippocampal formation [nTPM]":"4.5","Tissue RNA - hypothalamus [nTPM]":"5.6","Tissue RNA - kidney [nTPM]":"2.0","Tissue RNA - liver [nTPM]":"1.5","Tissue RNA - lung [nTPM]":"4.6","Tissue RNA - lymph node [nTPM]":"4.1","Tissue RNA - medulla oblongata [nTPM]":"7.0","Tissue RNA - midbrain [nTPM]":"5.0","Tissue RNA - ovary [nTPM]":"2.9","Tissue RNA - pancreas [nTPM]":"1.1","Tissue RNA - parathyroid gland [nTPM]":"1.7","Tissue RNA - pituitary gland [nTPM]":"2.7","Tissue RNA - placenta [nTPM]":"15.9","Tissue RNA - pons [nTPM]":"6.3","Tissue RNA - prostate [nTPM]":"3.3","Tissue RNA - rectum [nTPM]":"3.7","Tissue RNA - retina [nTPM]":"4.9","Tissue RNA - salivary gland [nTPM]":"1.6","Tissue RNA - seminal vesicle [nTPM]":"4.0","Tissue RNA - skeletal muscle [nTPM]":"1.3","Tissue RNA - skin 1 [nTPM]":"2.0","Tissue RNA - small intestine [nTPM]":"3.9","Tissue RNA - smooth muscle [nTPM]":"8.1","Tissue RNA - spinal cord [nTPM]":"5.6","Tissue RNA - spleen [nTPM]":"8.9","Tissue RNA - stomach 1 [nTPM]":"2.7","Tissue RNA - testis [nTPM]":"2.6","Tissue RNA - thalamus [nTPM]":"7.0","Tissue RNA - thymus [nTPM]":"1.4","Tissue RNA - thyroid gland [nTPM]":"2.2","Tissue RNA - tongue [nTPM]":"1.5","Tissue RNA - tonsil [nTPM]":"2.3","Tissue RNA - urinary bladder [nTPM]":"5.2","Tissue RNA - vagina [nTPM]":"4.0","Tissue RNA - white matter [nTPM]":"7.3","Cell RNA - A-431 [nTPM]":"1.6","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"21.8","Cell RNA - AN3-CA [nTPM]":"3.7","Cell RNA - ASC diff [nTPM]":"17.1","Cell RNA - ASC TERT1 [nTPM]":"20.6","Cell RNA - BEWO [nTPM]":"4.5","Cell RNA - BJ [nTPM]":"71.0","Cell RNA - BJ hTERT+ [nTPM]":"143.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"33.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"31.8","Cell RNA - CACO-2 [nTPM]":"25.6","Cell RNA - CAPAN-2 [nTPM]":"1.3","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.9","Cell RNA - fHDF\/TERT166 [nTPM]":"73.1","Cell RNA - GAMG [nTPM]":"1.6","Cell RNA - HaCaT [nTPM]":"1.1","Cell RNA - HAP1 [nTPM]":"2.8","Cell RNA - HBEC3-KT [nTPM]":"1.8","Cell RNA - HBF TERT88 [nTPM]":"19.8","Cell RNA - HDLM-2 [nTPM]":"110.7","Cell RNA - HEK 293 [nTPM]":"1.0","Cell RNA - HEL [nTPM]":"17.6","Cell RNA - HeLa [nTPM]":"1.8","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"5.7","Cell RNA - HL-60 [nTPM]":"0.6","Cell RNA - HMC-1 [nTPM]":"16.7","Cell RNA - HSkMC [nTPM]":"22.6","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"90.6","Cell RNA - hTERT-HME1 [nTPM]":"3.8","Cell RNA - hTERT-RPE1 [nTPM]":"12.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.7","Cell RNA - JURKAT [nTPM]":"0.8","Cell RNA - K-562 [nTPM]":"0.8","Cell RNA - Karpas-707 [nTPM]":"2.8","Cell RNA - LHCN-M2 [nTPM]":"6.4","Cell RNA - MCF7 [nTPM]":"4.1","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"6.5","Cell RNA - NTERA-2 [nTPM]":"12.0","Cell RNA - OE19 [nTPM]":"0.8","Cell RNA - PC-3 [nTPM]":"0.7","Cell RNA - REH [nTPM]":"2.0","Cell RNA - RH-30 [nTPM]":"3.1","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.3","Cell RNA - RT4 [nTPM]":"1.2","Cell RNA - SCLC-21H [nTPM]":"11.2","Cell RNA - SH-SY5Y [nTPM]":"12.8","Cell RNA - SiHa [nTPM]":"0.6","Cell RNA - SK-BR-3 [nTPM]":"1.1","Cell RNA - SK-MEL-30 [nTPM]":"14.7","Cell RNA - SuSa [nTPM]":"3.2","Cell RNA - T-47d [nTPM]":"2.3","Cell RNA - THP-1 [nTPM]":"1.3","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"245.9","Cell RNA - U-2 OS [nTPM]":"8.2","Cell RNA - U-2197 [nTPM]":"1.4","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"1.4","Cell RNA - U-266\/84 [nTPM]":"0.5","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"92.5","Cell RNA - U-937 [nTPM]":"6.8","Cell RNA - WM-115 [nTPM]":"549.6","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"6.0","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"11.7","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"3.5","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"2.5","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"9.3","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"2.6","Brain RNA - amygdala [nTPM]":"4.5","Brain RNA - basal ganglia [nTPM]":"4.7","Brain RNA - cerebellum [nTPM]":"4.5","Brain RNA - cerebral cortex [nTPM]":"5.3","Brain RNA - hippocampal formation [nTPM]":"4.5","Brain RNA - hypothalamus [nTPM]":"5.6","Brain RNA - medulla oblongata [nTPM]":"7.0","Brain RNA - midbrain [nTPM]":"5.0","Brain RNA - pons [nTPM]":"6.3","Brain RNA - spinal cord [nTPM]":"5.6","Brain RNA - thalamus [nTPM]":"7.0","Brain RNA - white matter [nTPM]":"7.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"14.0","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.8","Single Cell Type RNA - Endothelial cells [nTPM]":"1.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.5","Single Cell Type RNA - Fibroblasts [nTPM]":"7.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.9","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"12.5","Single Cell Type RNA - Langerhans cells [nTPM]":"2.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"12.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"30.0","Single Cell Type RNA - monocytes [nTPM]":"4.8","Single Cell Type RNA - Muller glia cells [nTPM]":"10.6","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.9","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"LPAR6","Gene synonym":["P2RY5","P2Y5"],"Ensembl":"ENSG00000139679","Gene description":"Lysophosphatidic acid receptor 6","Uniprot":["P43657"],"Chromosome":"13","Position":"48389567-48444704","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","Hypotrichosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"266.1","Basal squamous epithelial cells":"327.2","Early spermatids":"334.0","Langerhans cells":"703.7","Late spermatids":"321.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"21.6","HUVEC TERT2":"35.3","MOLT-4":"20.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028934"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA028934":"AB_2672833"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.22e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.60e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Tissue RNA - adipose tissue [nTPM]":"41.0","Tissue RNA - adrenal gland [nTPM]":"26.5","Tissue RNA - amygdala [nTPM]":"14.5","Tissue RNA - appendix [nTPM]":"26.8","Tissue RNA - basal ganglia [nTPM]":"14.7","Tissue RNA - bone marrow [nTPM]":"6.1","Tissue RNA - breast [nTPM]":"43.0","Tissue RNA - cerebellum [nTPM]":"15.2","Tissue RNA - cerebral cortex [nTPM]":"27.1","Tissue RNA - cervix [nTPM]":"41.9","Tissue RNA - choroid plexus [nTPM]":"18.3","Tissue RNA - colon [nTPM]":"22.1","Tissue RNA - duodenum [nTPM]":"15.0","Tissue RNA - endometrium 1 [nTPM]":"28.7","Tissue RNA - epididymis [nTPM]":"39.5","Tissue RNA - esophagus [nTPM]":"81.8","Tissue RNA - fallopian tube [nTPM]":"22.2","Tissue RNA - gallbladder [nTPM]":"35.5","Tissue RNA - heart muscle [nTPM]":"24.9","Tissue RNA - hippocampal formation [nTPM]":"14.0","Tissue RNA - hypothalamus [nTPM]":"15.8","Tissue RNA - kidney [nTPM]":"26.2","Tissue RNA - liver [nTPM]":"23.2","Tissue RNA - lung [nTPM]":"34.6","Tissue RNA - lymph node [nTPM]":"45.6","Tissue RNA - medulla oblongata [nTPM]":"19.0","Tissue RNA - midbrain [nTPM]":"16.4","Tissue RNA - ovary [nTPM]":"14.9","Tissue RNA - pancreas [nTPM]":"8.7","Tissue RNA - parathyroid gland [nTPM]":"9.7","Tissue RNA - pituitary gland [nTPM]":"15.9","Tissue RNA - placenta [nTPM]":"77.7","Tissue RNA - pons [nTPM]":"18.0","Tissue RNA - prostate [nTPM]":"60.7","Tissue RNA - rectum [nTPM]":"27.6","Tissue RNA - retina [nTPM]":"5.8","Tissue RNA - salivary gland [nTPM]":"59.7","Tissue RNA - seminal vesicle [nTPM]":"32.2","Tissue RNA - skeletal muscle [nTPM]":"9.0","Tissue RNA - skin 1 [nTPM]":"33.9","Tissue RNA - small intestine [nTPM]":"21.7","Tissue RNA - smooth muscle [nTPM]":"27.1","Tissue RNA - spinal cord [nTPM]":"18.2","Tissue RNA - spleen [nTPM]":"40.2","Tissue RNA - stomach 1 [nTPM]":"21.6","Tissue RNA - testis [nTPM]":"8.1","Tissue RNA - thalamus [nTPM]":"16.7","Tissue RNA - thymus [nTPM]":"36.4","Tissue RNA - thyroid gland [nTPM]":"24.3","Tissue RNA - tongue [nTPM]":"20.8","Tissue RNA - tonsil [nTPM]":"41.1","Tissue RNA - urinary bladder [nTPM]":"40.8","Tissue RNA - vagina [nTPM]":"75.1","Tissue RNA - white matter [nTPM]":"21.0","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"2.1","Cell RNA - AF22 [nTPM]":"21.6","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"7.0","Cell RNA - ASC TERT1 [nTPM]":"8.6","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"4.5","Cell RNA - BJ hTERT+ [nTPM]":"12.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.5","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"6.4","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"4.9","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"12.7","Cell RNA - HAP1 [nTPM]":"0.6","Cell RNA - HBEC3-KT [nTPM]":"7.2","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"4.3","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"15.9","Cell RNA - HHSteC [nTPM]":"4.6","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"11.5","Cell RNA - hTCEpi [nTPM]":"12.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.5","Cell RNA - hTERT-HME1 [nTPM]":"7.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"35.3","Cell RNA - JURKAT [nTPM]":"7.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"4.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"20.0","Cell RNA - NB-4 [nTPM]":"6.3","Cell RNA - NTERA-2 [nTPM]":"8.6","Cell RNA - OE19 [nTPM]":"0.4","Cell RNA - PC-3 [nTPM]":"5.9","Cell RNA - REH [nTPM]":"16.9","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"5.9","Cell RNA - RT4 [nTPM]":"13.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"4.5","Cell RNA - SuSa [nTPM]":"13.2","Cell RNA - T-47d [nTPM]":"2.2","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"9.1","Cell RNA - U-138 MG [nTPM]":"2.4","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"1.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.7","Cell RNA - U-937 [nTPM]":"1.1","Cell RNA - WM-115 [nTPM]":"7.8","Blood RNA - basophil [nTPM]":"1.3","Blood RNA - classical monocyte [nTPM]":"71.9","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"24.6","Blood RNA - intermediate monocyte [nTPM]":"112.0","Blood RNA - MAIT T-cell [nTPM]":"13.6","Blood RNA - memory B-cell [nTPM]":"1.2","Blood RNA - memory CD4 T-cell [nTPM]":"70.0","Blood RNA - memory CD8 T-cell [nTPM]":"29.4","Blood RNA - myeloid DC [nTPM]":"26.0","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"49.3","Blood RNA - naive CD8 T-cell [nTPM]":"15.6","Blood RNA - neutrophil [nTPM]":"5.9","Blood RNA - NK-cell [nTPM]":"6.9","Blood RNA - non-classical monocyte [nTPM]":"103.6","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"83.9","Blood RNA - total PBMC [nTPM]":"58.2","Brain RNA - amygdala [nTPM]":"14.5","Brain RNA - basal ganglia [nTPM]":"14.7","Brain RNA - cerebellum [nTPM]":"15.2","Brain RNA - cerebral cortex [nTPM]":"27.1","Brain RNA - hippocampal formation [nTPM]":"14.0","Brain RNA - hypothalamus [nTPM]":"15.8","Brain RNA - medulla oblongata [nTPM]":"19.0","Brain RNA - midbrain [nTPM]":"16.4","Brain RNA - pons [nTPM]":"18.0","Brain RNA - spinal cord [nTPM]":"18.2","Brain RNA - thalamus [nTPM]":"16.7","Brain RNA - white matter [nTPM]":"21.0","Single Cell Type RNA - Adipocytes [nTPM]":"266.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.7","Single Cell Type RNA - Astrocytes [nTPM]":"4.9","Single Cell Type RNA - B-cells [nTPM]":"5.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"120.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"196.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"155.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"327.2","Single Cell Type RNA - Bipolar cells [nTPM]":"1.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"30.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"76.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - dendritic cells [nTPM]":"22.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"10.4","Single Cell Type RNA - Early spermatids [nTPM]":"334.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.7","Single Cell Type RNA - Endothelial cells [nTPM]":"140.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.4","Single Cell Type RNA - Erythroid cells [nTPM]":"8.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.8","Single Cell Type RNA - Fibroblasts [nTPM]":"23.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.8","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"5.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"136.0","Single Cell Type RNA - Hepatocytes [nTPM]":"2.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"82.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.9","Single Cell Type RNA - Ionocytes [nTPM]":"42.7","Single Cell Type RNA - Kupffer cells [nTPM]":"74.0","Single Cell Type RNA - Langerhans cells [nTPM]":"703.7","Single Cell Type RNA - Late spermatids [nTPM]":"321.7","Single Cell Type RNA - Leydig cells [nTPM]":"22.7","Single Cell Type RNA - Macrophages [nTPM]":"111.9","Single Cell Type RNA - Melanocytes [nTPM]":"49.8","Single Cell Type RNA - Microglial cells [nTPM]":"177.1","Single Cell Type RNA - monocytes [nTPM]":"76.4","Single Cell Type RNA - Muller glia cells [nTPM]":"11.3","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.7","Single Cell Type RNA - Paneth cells [nTPM]":"4.1","Single Cell Type RNA - Peritubular cells [nTPM]":"15.8","Single Cell Type RNA - Plasma cells [nTPM]":"6.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"107.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"25.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"49.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.3","Single Cell Type RNA - Spermatocytes [nTPM]":"2.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"182.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"142.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"52.3","Single Cell Type RNA - Theca cells [nTPM]":"14.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.6","Single Cell Type RNA - Urothelial cells [nTPM]":"143.5"},{"Gene":"LPIN1","Gene synonym":["KIAA0188"],"Ensembl":"ENSG00000134324","Gene description":"Lipin 1","Uniprot":["Q14693"],"Chromosome":"2","Position":"11677595-11827409","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism","Transcription","Transcription regulation"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"193.5","tongue":"137.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Late spermatids":"1705.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024591","HPA038021"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA024591":null,"HPA038021":"AB_10669514"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-1"},"Tissue RNA - adipose tissue [nTPM]":"36.2","Tissue RNA - adrenal gland [nTPM]":"15.0","Tissue RNA - amygdala [nTPM]":"29.0","Tissue RNA - appendix [nTPM]":"14.9","Tissue RNA - basal ganglia [nTPM]":"30.6","Tissue RNA - bone marrow [nTPM]":"8.6","Tissue RNA - breast [nTPM]":"36.7","Tissue RNA - cerebellum [nTPM]":"24.2","Tissue RNA - cerebral cortex [nTPM]":"24.9","Tissue RNA - cervix [nTPM]":"25.1","Tissue RNA - choroid plexus [nTPM]":"21.9","Tissue RNA - colon [nTPM]":"16.7","Tissue RNA - duodenum [nTPM]":"11.9","Tissue RNA - endometrium 1 [nTPM]":"16.6","Tissue RNA - epididymis [nTPM]":"19.0","Tissue RNA - esophagus [nTPM]":"40.5","Tissue RNA - fallopian tube [nTPM]":"15.6","Tissue RNA - gallbladder [nTPM]":"13.0","Tissue RNA - heart muscle [nTPM]":"20.1","Tissue RNA - hippocampal formation [nTPM]":"21.0","Tissue RNA - hypothalamus [nTPM]":"32.1","Tissue RNA - kidney [nTPM]":"14.9","Tissue RNA - liver [nTPM]":"27.0","Tissue RNA - lung [nTPM]":"16.1","Tissue RNA - lymph node [nTPM]":"22.3","Tissue RNA - medulla oblongata [nTPM]":"31.8","Tissue RNA - midbrain [nTPM]":"38.2","Tissue RNA - ovary [nTPM]":"31.5","Tissue RNA - pancreas [nTPM]":"9.9","Tissue RNA - parathyroid gland [nTPM]":"23.1","Tissue RNA - pituitary gland [nTPM]":"34.2","Tissue RNA - placenta [nTPM]":"11.7","Tissue RNA - pons [nTPM]":"35.3","Tissue RNA - prostate [nTPM]":"13.7","Tissue RNA - rectum [nTPM]":"8.5","Tissue RNA - retina [nTPM]":"14.8","Tissue RNA - salivary gland [nTPM]":"27.3","Tissue RNA - seminal vesicle [nTPM]":"14.1","Tissue RNA - skeletal muscle [nTPM]":"193.5","Tissue RNA - skin 1 [nTPM]":"13.4","Tissue RNA - small intestine [nTPM]":"19.7","Tissue RNA - smooth muscle [nTPM]":"13.0","Tissue RNA - spinal cord [nTPM]":"14.1","Tissue RNA - spleen [nTPM]":"14.8","Tissue RNA - stomach 1 [nTPM]":"14.9","Tissue RNA - testis [nTPM]":"57.4","Tissue RNA - thalamus [nTPM]":"35.0","Tissue RNA - thymus [nTPM]":"16.1","Tissue RNA - thyroid gland [nTPM]":"14.6","Tissue RNA - tongue [nTPM]":"137.2","Tissue RNA - tonsil [nTPM]":"26.3","Tissue RNA - urinary bladder [nTPM]":"19.9","Tissue RNA - vagina [nTPM]":"23.1","Tissue RNA - white matter [nTPM]":"18.8","Cell RNA - A-431 [nTPM]":"16.2","Cell RNA - A549 [nTPM]":"18.0","Cell RNA - AF22 [nTPM]":"15.9","Cell RNA - AN3-CA [nTPM]":"34.9","Cell RNA - ASC diff [nTPM]":"71.4","Cell RNA - ASC TERT1 [nTPM]":"77.9","Cell RNA - BEWO [nTPM]":"7.8","Cell RNA - BJ [nTPM]":"22.2","Cell RNA - BJ hTERT+ [nTPM]":"38.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.3","Cell RNA - CACO-2 [nTPM]":"6.9","Cell RNA - CAPAN-2 [nTPM]":"15.4","Cell RNA - Daudi [nTPM]":"8.2","Cell RNA - EFO-21 [nTPM]":"2.9","Cell RNA - fHDF\/TERT166 [nTPM]":"18.6","Cell RNA - GAMG [nTPM]":"41.6","Cell RNA - HaCaT [nTPM]":"17.3","Cell RNA - HAP1 [nTPM]":"17.4","Cell RNA - HBEC3-KT [nTPM]":"49.2","Cell RNA - HBF TERT88 [nTPM]":"12.8","Cell RNA - HDLM-2 [nTPM]":"32.9","Cell RNA - HEK 293 [nTPM]":"9.8","Cell RNA - HEL [nTPM]":"20.3","Cell RNA - HeLa [nTPM]":"11.5","Cell RNA - Hep G2 [nTPM]":"9.7","Cell RNA - HHSteC [nTPM]":"25.1","Cell RNA - HL-60 [nTPM]":"14.1","Cell RNA - HMC-1 [nTPM]":"90.1","Cell RNA - HSkMC [nTPM]":"71.1","Cell RNA - hTCEpi [nTPM]":"21.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"57.9","Cell RNA - hTERT-HME1 [nTPM]":"22.6","Cell RNA - hTERT-RPE1 [nTPM]":"41.7","Cell RNA - HUVEC TERT2 [nTPM]":"28.0","Cell RNA - JURKAT [nTPM]":"19.6","Cell RNA - K-562 [nTPM]":"27.4","Cell RNA - Karpas-707 [nTPM]":"68.3","Cell RNA - LHCN-M2 [nTPM]":"10.4","Cell RNA - MCF7 [nTPM]":"6.4","Cell RNA - MOLT-4 [nTPM]":"13.5","Cell RNA - NB-4 [nTPM]":"12.0","Cell RNA - NTERA-2 [nTPM]":"16.2","Cell RNA - OE19 [nTPM]":"5.5","Cell RNA - PC-3 [nTPM]":"18.9","Cell RNA - REH [nTPM]":"18.1","Cell RNA - RH-30 [nTPM]":"28.6","Cell RNA - RPMI-8226 [nTPM]":"52.0","Cell RNA - RPTEC TERT1 [nTPM]":"36.9","Cell RNA - RT4 [nTPM]":"10.0","Cell RNA - SCLC-21H [nTPM]":"42.8","Cell RNA - SH-SY5Y [nTPM]":"33.6","Cell RNA - SiHa [nTPM]":"8.0","Cell RNA - SK-BR-3 [nTPM]":"19.7","Cell RNA - SK-MEL-30 [nTPM]":"51.9","Cell RNA - SuSa [nTPM]":"15.0","Cell RNA - T-47d [nTPM]":"4.9","Cell RNA - THP-1 [nTPM]":"7.9","Cell RNA - TIME [nTPM]":"19.5","Cell RNA - U-138 MG [nTPM]":"22.1","Cell RNA - U-2 OS [nTPM]":"19.9","Cell RNA - U-2197 [nTPM]":"14.4","Cell RNA - U-251 MG [nTPM]":"19.0","Cell RNA - U-266\/70 [nTPM]":"108.0","Cell RNA - U-266\/84 [nTPM]":"92.0","Cell RNA - U-698 [nTPM]":"15.2","Cell RNA - U-87 MG [nTPM]":"31.3","Cell RNA - U-937 [nTPM]":"24.7","Cell RNA - WM-115 [nTPM]":"16.6","Blood RNA - basophil [nTPM]":"11.2","Blood RNA - classical monocyte [nTPM]":"2.9","Blood RNA - eosinophil [nTPM]":"13.4","Blood RNA - gdT-cell [nTPM]":"10.3","Blood RNA - intermediate monocyte [nTPM]":"2.3","Blood RNA - MAIT T-cell [nTPM]":"11.2","Blood RNA - memory B-cell [nTPM]":"7.3","Blood RNA - memory CD4 T-cell [nTPM]":"9.9","Blood RNA - memory CD8 T-cell [nTPM]":"10.1","Blood RNA - myeloid DC [nTPM]":"2.7","Blood RNA - naive B-cell [nTPM]":"5.1","Blood RNA - naive CD4 T-cell [nTPM]":"8.6","Blood RNA - naive CD8 T-cell [nTPM]":"7.2","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"9.5","Blood RNA - non-classical monocyte [nTPM]":"2.3","Blood RNA - plasmacytoid DC [nTPM]":"10.3","Blood RNA - T-reg [nTPM]":"12.2","Blood RNA - total PBMC [nTPM]":"3.7","Brain RNA - amygdala [nTPM]":"29.0","Brain RNA - basal ganglia [nTPM]":"30.6","Brain RNA - cerebellum [nTPM]":"24.2","Brain RNA - cerebral cortex [nTPM]":"24.9","Brain RNA - hippocampal formation [nTPM]":"21.0","Brain RNA - hypothalamus [nTPM]":"32.1","Brain RNA - medulla oblongata [nTPM]":"31.8","Brain RNA - midbrain [nTPM]":"38.2","Brain RNA - pons [nTPM]":"35.3","Brain RNA - spinal cord [nTPM]":"14.1","Brain RNA - thalamus [nTPM]":"35.0","Brain RNA - white matter [nTPM]":"18.8","Single Cell Type RNA - Adipocytes [nTPM]":"15.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"56.8","Single Cell Type RNA - Astrocytes [nTPM]":"167.8","Single Cell Type RNA - B-cells [nTPM]":"46.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"19.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"45.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Bipolar cells [nTPM]":"48.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"32.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"22.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"59.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"31.5","Single Cell Type RNA - Club cells [nTPM]":"43.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"85.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.7","Single Cell Type RNA - dendritic cells [nTPM]":"68.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"21.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"23.0","Single Cell Type RNA - Early spermatids [nTPM]":"338.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"44.4","Single Cell Type RNA - Endothelial cells [nTPM]":"25.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"36.2","Single Cell Type RNA - Erythroid cells [nTPM]":"9.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"55.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"28.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.0","Single Cell Type RNA - Fibroblasts [nTPM]":"28.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"76.5","Single Cell Type RNA - granulocytes [nTPM]":"35.4","Single Cell Type RNA - Granulosa cells [nTPM]":"13.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.5","Single Cell Type RNA - Hepatocytes [nTPM]":"48.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.9","Single Cell Type RNA - Horizontal cells [nTPM]":"48.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"71.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"25.2","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"15.7","Single Cell Type RNA - Langerhans cells [nTPM]":"39.4","Single Cell Type RNA - Late spermatids [nTPM]":"1705.8","Single Cell Type RNA - Leydig cells [nTPM]":"119.0","Single Cell Type RNA - Macrophages [nTPM]":"25.5","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"15.4","Single Cell Type RNA - Muller glia cells [nTPM]":"14.7","Single Cell Type RNA - NK-cells [nTPM]":"66.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"41.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"43.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"36.5","Single Cell Type RNA - Paneth cells [nTPM]":"29.7","Single Cell Type RNA - Peritubular cells [nTPM]":"179.8","Single Cell Type RNA - Plasma cells [nTPM]":"76.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"34.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"52.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"49.0","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"32.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.4","Single Cell Type RNA - Spermatocytes [nTPM]":"20.6","Single Cell Type RNA - Spermatogonia [nTPM]":"19.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.3","Single Cell Type RNA - T-cells [nTPM]":"73.2","Single Cell Type RNA - Theca cells [nTPM]":"26.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.3","Single Cell Type RNA - Urothelial cells [nTPM]":"31.3"},{"Gene":"LPIN2","Gene synonym":["KIAA0249"],"Ensembl":"ENSG00000101577","Gene description":"Lipin 2","Uniprot":["Q92539"],"Chromosome":"18","Position":"2916994-3013144","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism","Transcription","Transcription regulation"],"Molecular function":["Hydrolase"],"Disease involvement":["Congenital dyserythropoietic anemia","Disease variant","Hereditary hemolytic anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"165.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"154.4","Granulosa cells":"323.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"23.4","NK-cells":"12.5","T-cells":"12.1"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015223","HPA017857","HPA030550"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane","Actin filaments"],"Antibody RRID":{"CAB015223":null,"HPA017857":"AB_1852904","HPA030550":"AB_2673519"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.01e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.7","Tissue RNA - adrenal gland [nTPM]":"9.3","Tissue RNA - amygdala [nTPM]":"17.9","Tissue RNA - appendix [nTPM]":"21.2","Tissue RNA - basal ganglia [nTPM]":"19.9","Tissue RNA - bone marrow [nTPM]":"19.8","Tissue RNA - breast [nTPM]":"9.8","Tissue RNA - cerebellum [nTPM]":"14.6","Tissue RNA - cerebral cortex [nTPM]":"17.4","Tissue RNA - cervix [nTPM]":"9.7","Tissue RNA - choroid plexus [nTPM]":"16.6","Tissue RNA - colon [nTPM]":"13.9","Tissue RNA - duodenum [nTPM]":"62.8","Tissue RNA - endometrium 1 [nTPM]":"9.8","Tissue RNA - epididymis [nTPM]":"6.7","Tissue RNA - esophagus [nTPM]":"10.0","Tissue RNA - fallopian tube [nTPM]":"9.5","Tissue RNA - gallbladder [nTPM]":"25.7","Tissue RNA - heart muscle [nTPM]":"7.2","Tissue RNA - hippocampal formation [nTPM]":"16.1","Tissue RNA - hypothalamus [nTPM]":"24.2","Tissue RNA - kidney [nTPM]":"26.4","Tissue RNA - liver [nTPM]":"165.8","Tissue RNA - lung [nTPM]":"21.2","Tissue RNA - lymph node [nTPM]":"24.3","Tissue RNA - medulla oblongata [nTPM]":"22.7","Tissue RNA - midbrain [nTPM]":"22.0","Tissue RNA - ovary [nTPM]":"13.2","Tissue RNA - pancreas [nTPM]":"16.4","Tissue RNA - parathyroid gland [nTPM]":"13.5","Tissue RNA - pituitary gland [nTPM]":"10.9","Tissue RNA - placenta [nTPM]":"15.7","Tissue RNA - pons [nTPM]":"24.2","Tissue RNA - prostate [nTPM]":"9.0","Tissue RNA - rectum [nTPM]":"12.5","Tissue RNA - retina [nTPM]":"10.7","Tissue RNA - salivary gland [nTPM]":"7.4","Tissue RNA - seminal vesicle [nTPM]":"8.0","Tissue RNA - skeletal muscle [nTPM]":"2.7","Tissue RNA - skin 1 [nTPM]":"3.6","Tissue RNA - small intestine [nTPM]":"39.9","Tissue RNA - smooth muscle [nTPM]":"9.6","Tissue RNA - spinal cord [nTPM]":"15.6","Tissue RNA - spleen [nTPM]":"20.3","Tissue RNA - stomach 1 [nTPM]":"28.1","Tissue RNA - testis [nTPM]":"22.0","Tissue RNA - thalamus [nTPM]":"28.8","Tissue RNA - thymus [nTPM]":"18.9","Tissue RNA - thyroid gland [nTPM]":"12.1","Tissue RNA - tongue [nTPM]":"3.0","Tissue RNA - tonsil [nTPM]":"19.2","Tissue RNA - urinary bladder [nTPM]":"9.9","Tissue RNA - vagina [nTPM]":"6.0","Tissue RNA - white matter [nTPM]":"14.3","Cell RNA - A-431 [nTPM]":"8.7","Cell RNA - A549 [nTPM]":"12.0","Cell RNA - AF22 [nTPM]":"17.1","Cell RNA - AN3-CA [nTPM]":"6.6","Cell RNA - ASC diff [nTPM]":"31.7","Cell RNA - ASC TERT1 [nTPM]":"27.4","Cell RNA - BEWO [nTPM]":"10.5","Cell RNA - BJ [nTPM]":"17.4","Cell RNA - BJ hTERT+ [nTPM]":"22.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.9","Cell RNA - CACO-2 [nTPM]":"16.7","Cell RNA - CAPAN-2 [nTPM]":"7.1","Cell RNA - Daudi [nTPM]":"5.4","Cell RNA - EFO-21 [nTPM]":"10.8","Cell RNA - fHDF\/TERT166 [nTPM]":"30.2","Cell RNA - GAMG [nTPM]":"30.2","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"13.8","Cell RNA - HBEC3-KT [nTPM]":"6.3","Cell RNA - HBF TERT88 [nTPM]":"13.2","Cell RNA - HDLM-2 [nTPM]":"11.2","Cell RNA - HEK 293 [nTPM]":"2.7","Cell RNA - HEL [nTPM]":"13.3","Cell RNA - HeLa [nTPM]":"10.0","Cell RNA - Hep G2 [nTPM]":"19.4","Cell RNA - HHSteC [nTPM]":"27.2","Cell RNA - HL-60 [nTPM]":"11.2","Cell RNA - HMC-1 [nTPM]":"17.0","Cell RNA - HSkMC [nTPM]":"27.4","Cell RNA - hTCEpi [nTPM]":"4.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.5","Cell RNA - hTERT-HME1 [nTPM]":"17.2","Cell RNA - hTERT-RPE1 [nTPM]":"28.2","Cell RNA - HUVEC TERT2 [nTPM]":"23.4","Cell RNA - JURKAT [nTPM]":"14.8","Cell RNA - K-562 [nTPM]":"12.8","Cell RNA - Karpas-707 [nTPM]":"3.5","Cell RNA - LHCN-M2 [nTPM]":"28.2","Cell RNA - MCF7 [nTPM]":"7.2","Cell RNA - MOLT-4 [nTPM]":"15.0","Cell RNA - NB-4 [nTPM]":"12.0","Cell RNA - NTERA-2 [nTPM]":"5.7","Cell RNA - OE19 [nTPM]":"13.7","Cell RNA - PC-3 [nTPM]":"13.1","Cell RNA - REH [nTPM]":"26.7","Cell RNA - RH-30 [nTPM]":"14.0","Cell RNA - RPMI-8226 [nTPM]":"23.2","Cell RNA - RPTEC TERT1 [nTPM]":"17.6","Cell RNA - RT4 [nTPM]":"20.0","Cell RNA - SCLC-21H [nTPM]":"14.4","Cell RNA - SH-SY5Y [nTPM]":"10.2","Cell RNA - SiHa [nTPM]":"18.4","Cell RNA - SK-BR-3 [nTPM]":"9.1","Cell RNA - SK-MEL-30 [nTPM]":"6.8","Cell RNA - SuSa [nTPM]":"10.7","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"18.0","Cell RNA - TIME [nTPM]":"31.2","Cell RNA - U-138 MG [nTPM]":"25.3","Cell RNA - U-2 OS [nTPM]":"28.7","Cell RNA - U-2197 [nTPM]":"31.7","Cell RNA - U-251 MG [nTPM]":"14.6","Cell RNA - U-266\/70 [nTPM]":"5.0","Cell RNA - U-266\/84 [nTPM]":"7.9","Cell RNA - U-698 [nTPM]":"12.3","Cell RNA - U-87 MG [nTPM]":"22.1","Cell RNA - U-937 [nTPM]":"12.2","Cell RNA - WM-115 [nTPM]":"8.1","Blood RNA - basophil [nTPM]":"8.7","Blood RNA - classical monocyte [nTPM]":"2.4","Blood RNA - eosinophil [nTPM]":"7.8","Blood RNA - gdT-cell [nTPM]":"11.8","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"12.1","Blood RNA - memory B-cell [nTPM]":"1.0","Blood RNA - memory CD4 T-cell [nTPM]":"9.2","Blood RNA - memory CD8 T-cell [nTPM]":"7.2","Blood RNA - myeloid DC [nTPM]":"1.0","Blood RNA - naive B-cell [nTPM]":"1.7","Blood RNA - naive CD4 T-cell [nTPM]":"9.1","Blood RNA - naive CD8 T-cell [nTPM]":"6.3","Blood RNA - neutrophil [nTPM]":"23.4","Blood RNA - NK-cell [nTPM]":"12.5","Blood RNA - non-classical monocyte [nTPM]":"0.8","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"9.2","Blood RNA - total PBMC [nTPM]":"3.2","Brain RNA - amygdala [nTPM]":"17.9","Brain RNA - basal ganglia [nTPM]":"19.9","Brain RNA - cerebellum [nTPM]":"14.6","Brain RNA - cerebral cortex [nTPM]":"17.4","Brain RNA - hippocampal formation [nTPM]":"16.1","Brain RNA - hypothalamus [nTPM]":"24.2","Brain RNA - medulla oblongata [nTPM]":"22.7","Brain RNA - midbrain [nTPM]":"22.0","Brain RNA - pons [nTPM]":"24.2","Brain RNA - spinal cord [nTPM]":"15.6","Brain RNA - thalamus [nTPM]":"28.8","Brain RNA - white matter [nTPM]":"14.3","Single Cell Type RNA - Adipocytes [nTPM]":"17.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"67.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"44.0","Single Cell Type RNA - Astrocytes [nTPM]":"55.2","Single Cell Type RNA - B-cells [nTPM]":"20.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"35.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"154.4","Single Cell Type RNA - Club cells [nTPM]":"23.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.2","Single Cell Type RNA - dendritic cells [nTPM]":"41.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"45.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"11.8","Single Cell Type RNA - Early spermatids [nTPM]":"3.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"48.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"33.3","Single Cell Type RNA - Endothelial cells [nTPM]":"18.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.9","Single Cell Type RNA - Erythroid cells [nTPM]":"138.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"26.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.3","Single Cell Type RNA - Fibroblasts [nTPM]":"25.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"103.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"64.4","Single Cell Type RNA - granulocytes [nTPM]":"12.6","Single Cell Type RNA - Granulosa cells [nTPM]":"323.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.2","Single Cell Type RNA - Hepatocytes [nTPM]":"131.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.1","Single Cell Type RNA - Horizontal cells [nTPM]":"116.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"65.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"36.8","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"26.8","Single Cell Type RNA - Langerhans cells [nTPM]":"8.9","Single Cell Type RNA - Late spermatids [nTPM]":"11.0","Single Cell Type RNA - Leydig cells [nTPM]":"22.7","Single Cell Type RNA - Macrophages [nTPM]":"31.1","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"79.6","Single Cell Type RNA - monocytes [nTPM]":"31.2","Single Cell Type RNA - Muller glia cells [nTPM]":"16.7","Single Cell Type RNA - NK-cells [nTPM]":"59.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"37.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.2","Single Cell Type RNA - Paneth cells [nTPM]":"21.6","Single Cell Type RNA - Peritubular cells [nTPM]":"31.2","Single Cell Type RNA - Plasma cells [nTPM]":"16.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"21.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"92.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"54.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.1","Single Cell Type RNA - Spermatocytes [nTPM]":"26.5","Single Cell Type RNA - Spermatogonia [nTPM]":"73.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"49.5","Single Cell Type RNA - T-cells [nTPM]":"58.9","Single Cell Type RNA - Theca cells [nTPM]":"20.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.0","Single Cell Type RNA - Urothelial cells [nTPM]":"14.1"},{"Gene":"LRAT","Gene synonym":["LCA14"],"Ensembl":"ENSG00000121207","Gene description":"Lecithin retinol acyltransferase","Uniprot":["O95237"],"Chromosome":"4","Position":"154626945-154753120","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant","Leber congenital amaurosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"2.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Granulosa cells":"104.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"1.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"NTERA-2":"15.3"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070726"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Endoplasmic reticulum","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"HPA070726":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-6"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.6","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.7","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"2.6","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"1.6","Tissue RNA - colon [nTPM]":"0.5","Tissue RNA - duodenum [nTPM]":"1.2","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"1.2","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"2.1","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"1.0","Tissue RNA - midbrain [nTPM]":"1.1","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"1.3","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"1.0","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.5","Tissue RNA - skeletal muscle [nTPM]":"0.8","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"1.6","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.7","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"0.7","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"1.5","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.9","Cell RNA - A-431 [nTPM]":"0.5","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"15.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"1.4","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"1.9","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"2.2","Brain RNA - amygdala [nTPM]":"0.6","Brain RNA - basal ganglia [nTPM]":"0.7","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"2.6","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"1.2","Brain RNA - medulla oblongata [nTPM]":"1.0","Brain RNA - midbrain [nTPM]":"1.1","Brain RNA - pons [nTPM]":"1.3","Brain RNA - spinal cord [nTPM]":"0.7","Brain RNA - thalamus [nTPM]":"0.7","Brain RNA - white matter [nTPM]":"0.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.4","Single Cell Type RNA - Astrocytes [nTPM]":"4.6","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"1.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.2","Single Cell Type RNA - Early spermatids [nTPM]":"15.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"104.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"2.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.9","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"2.8","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"3.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.1","Single Cell Type RNA - Spermatocytes [nTPM]":"10.5","Single Cell Type RNA - Spermatogonia [nTPM]":"4.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"LRP1","Gene synonym":["A2MR","APOER","APR","CD91","IGFBP-3R","IGFBP3R1","LRP","LRP1A"],"Ensembl":"ENSG00000123384","Gene description":"LDL receptor related protein 1","Uniprot":["Q07954"],"Chromosome":"12","Position":"57128483-57213361","Protein class":["Candidate cardiovascular disease genes","CD markers","Disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Endocytosis"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"109.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Fibroblasts":"273.4","Hepatocytes":"188.4","Leydig cells":"233.3","Peritubular cells":"184.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"18","RNA blood cell specific nTPM":{"classical monocyte":"4.3","intermediate monocyte":"2.2","myeloid DC":"1.6","non-classical monocyte":"2.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"21","RNA blood lineage specific nTPM":{"dendritic cells":"1.6","monocytes":"4.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"484.8","ASC TERT1":"488.4","fHDF\/TERT166":"222.2","HSkMC":"318.5","hTERT-RPE1":"248.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004182","CAB018621","HPA022903"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"180000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB018621":"AB_627893","HPA004182":"AB_2667163","HPA022903":"AB_10602426"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.52e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.29e-5"},"Tissue RNA - adipose tissue [nTPM]":"109.2","Tissue RNA - adrenal gland [nTPM]":"14.1","Tissue RNA - amygdala [nTPM]":"21.3","Tissue RNA - appendix [nTPM]":"29.0","Tissue RNA - basal ganglia [nTPM]":"36.3","Tissue RNA - bone marrow [nTPM]":"8.2","Tissue RNA - breast [nTPM]":"40.0","Tissue RNA - cerebellum [nTPM]":"30.2","Tissue RNA - cerebral cortex [nTPM]":"19.7","Tissue RNA - cervix [nTPM]":"32.3","Tissue RNA - choroid plexus [nTPM]":"8.0","Tissue RNA - colon [nTPM]":"24.1","Tissue RNA - duodenum [nTPM]":"23.2","Tissue RNA - endometrium 1 [nTPM]":"36.9","Tissue RNA - epididymis [nTPM]":"6.2","Tissue RNA - esophagus [nTPM]":"19.3","Tissue RNA - fallopian tube [nTPM]":"30.3","Tissue RNA - gallbladder [nTPM]":"31.5","Tissue RNA - heart muscle [nTPM]":"35.5","Tissue RNA - hippocampal formation [nTPM]":"16.7","Tissue RNA - hypothalamus [nTPM]":"21.9","Tissue RNA - kidney [nTPM]":"5.7","Tissue RNA - liver [nTPM]":"35.0","Tissue RNA - lung [nTPM]":"34.0","Tissue RNA - lymph node [nTPM]":"4.9","Tissue RNA - medulla oblongata [nTPM]":"46.0","Tissue RNA - midbrain [nTPM]":"31.5","Tissue RNA - ovary [nTPM]":"71.0","Tissue RNA - pancreas [nTPM]":"10.7","Tissue RNA - parathyroid gland [nTPM]":"7.8","Tissue RNA - pituitary gland [nTPM]":"10.2","Tissue RNA - placenta [nTPM]":"39.8","Tissue RNA - pons [nTPM]":"27.9","Tissue RNA - prostate [nTPM]":"13.8","Tissue RNA - rectum [nTPM]":"11.2","Tissue RNA - retina [nTPM]":"9.9","Tissue RNA - salivary gland [nTPM]":"20.3","Tissue RNA - seminal vesicle [nTPM]":"20.2","Tissue RNA - skeletal muscle [nTPM]":"13.0","Tissue RNA - skin 1 [nTPM]":"20.4","Tissue RNA - small intestine [nTPM]":"18.4","Tissue RNA - smooth muscle [nTPM]":"28.9","Tissue RNA - spinal cord [nTPM]":"27.1","Tissue RNA - spleen [nTPM]":"13.6","Tissue RNA - stomach 1 [nTPM]":"15.1","Tissue RNA - testis [nTPM]":"7.3","Tissue RNA - thalamus [nTPM]":"48.9","Tissue RNA - thymus [nTPM]":"5.6","Tissue RNA - thyroid gland [nTPM]":"17.6","Tissue RNA - tongue [nTPM]":"23.5","Tissue RNA - tonsil [nTPM]":"2.7","Tissue RNA - urinary bladder [nTPM]":"25.5","Tissue RNA - vagina [nTPM]":"29.3","Tissue RNA - white matter [nTPM]":"27.6","Cell RNA - A-431 [nTPM]":"7.7","Cell RNA - A549 [nTPM]":"14.5","Cell RNA - AF22 [nTPM]":"30.4","Cell RNA - AN3-CA [nTPM]":"24.2","Cell RNA - ASC diff [nTPM]":"484.8","Cell RNA - ASC TERT1 [nTPM]":"488.4","Cell RNA - BEWO [nTPM]":"91.2","Cell RNA - BJ [nTPM]":"85.3","Cell RNA - BJ hTERT+ [nTPM]":"109.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"27.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"26.7","Cell RNA - CACO-2 [nTPM]":"26.9","Cell RNA - CAPAN-2 [nTPM]":"12.4","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"10.4","Cell RNA - fHDF\/TERT166 [nTPM]":"222.2","Cell RNA - GAMG [nTPM]":"6.0","Cell RNA - HaCaT [nTPM]":"33.6","Cell RNA - HAP1 [nTPM]":"5.3","Cell RNA - HBEC3-KT [nTPM]":"8.7","Cell RNA - HBF TERT88 [nTPM]":"9.7","Cell RNA - HDLM-2 [nTPM]":"0.7","Cell RNA - HEK 293 [nTPM]":"1.3","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"17.9","Cell RNA - Hep G2 [nTPM]":"56.4","Cell RNA - HHSteC [nTPM]":"66.5","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"14.6","Cell RNA - HSkMC [nTPM]":"318.5","Cell RNA - hTCEpi [nTPM]":"3.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"61.8","Cell RNA - hTERT-HME1 [nTPM]":"7.2","Cell RNA - hTERT-RPE1 [nTPM]":"248.7","Cell RNA - HUVEC TERT2 [nTPM]":"1.7","Cell RNA - JURKAT [nTPM]":"1.1","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"1.3","Cell RNA - LHCN-M2 [nTPM]":"87.2","Cell RNA - MCF7 [nTPM]":"1.7","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"34.8","Cell RNA - OE19 [nTPM]":"11.0","Cell RNA - PC-3 [nTPM]":"8.8","Cell RNA - REH [nTPM]":"3.2","Cell RNA - RH-30 [nTPM]":"171.0","Cell RNA - RPMI-8226 [nTPM]":"1.6","Cell RNA - RPTEC TERT1 [nTPM]":"1.9","Cell RNA - RT4 [nTPM]":"2.2","Cell RNA - SCLC-21H [nTPM]":"1.4","Cell RNA - SH-SY5Y [nTPM]":"16.4","Cell RNA - SiHa [nTPM]":"19.0","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"13.2","Cell RNA - SuSa [nTPM]":"42.0","Cell RNA - T-47d [nTPM]":"2.9","Cell RNA - THP-1 [nTPM]":"1.2","Cell RNA - TIME [nTPM]":"1.2","Cell RNA - U-138 MG [nTPM]":"96.0","Cell RNA - U-2 OS [nTPM]":"35.0","Cell RNA - U-2197 [nTPM]":"53.9","Cell RNA - U-251 MG [nTPM]":"5.2","Cell RNA - U-266\/70 [nTPM]":"1.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"167.4","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"18.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"4.3","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"2.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"1.6","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"2.4","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.6","Brain RNA - amygdala [nTPM]":"21.3","Brain RNA - basal ganglia [nTPM]":"36.3","Brain RNA - cerebellum [nTPM]":"30.2","Brain RNA - cerebral cortex [nTPM]":"19.7","Brain RNA - hippocampal formation [nTPM]":"16.7","Brain RNA - hypothalamus [nTPM]":"21.9","Brain RNA - medulla oblongata [nTPM]":"46.0","Brain RNA - midbrain [nTPM]":"31.5","Brain RNA - pons [nTPM]":"27.9","Brain RNA - spinal cord [nTPM]":"27.1","Brain RNA - thalamus [nTPM]":"48.9","Brain RNA - white matter [nTPM]":"27.6","Single Cell Type RNA - Adipocytes [nTPM]":"24.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.4","Single Cell Type RNA - Astrocytes [nTPM]":"113.6","Single Cell Type RNA - B-cells [nTPM]":"3.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"24.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"28.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.9","Single Cell Type RNA - Bipolar cells [nTPM]":"29.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"19.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"14.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"87.5","Single Cell Type RNA - dendritic cells [nTPM]":"1.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"81.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"7.4","Single Cell Type RNA - Early spermatids [nTPM]":"1.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"111.4","Single Cell Type RNA - Endothelial cells [nTPM]":"13.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"39.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"53.0","Single Cell Type RNA - Fibroblasts [nTPM]":"273.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"49.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.2","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"36.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"188.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"73.8","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"41.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.1","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"145.3","Single Cell Type RNA - Langerhans cells [nTPM]":"28.6","Single Cell Type RNA - Late spermatids [nTPM]":"8.4","Single Cell Type RNA - Leydig cells [nTPM]":"233.3","Single Cell Type RNA - Macrophages [nTPM]":"102.9","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"89.9","Single Cell Type RNA - monocytes [nTPM]":"48.8","Single Cell Type RNA - Muller glia cells [nTPM]":"154.7","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"173.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.7","Single Cell Type RNA - Paneth cells [nTPM]":"27.2","Single Cell Type RNA - Peritubular cells [nTPM]":"184.3","Single Cell Type RNA - Plasma cells [nTPM]":"4.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"86.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.3","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"129.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"77.0","Single Cell Type RNA - Spermatocytes [nTPM]":"1.6","Single Cell Type RNA - Spermatogonia [nTPM]":"2.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"35.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"125.9","Single Cell Type RNA - T-cells [nTPM]":"4.2","Single Cell Type RNA - Theca cells [nTPM]":"11.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"25.0","Single Cell Type RNA - Urothelial cells [nTPM]":"12.3"},{"Gene":"LRP2","Gene synonym":["DBS","gp330"],"Ensembl":"ENSG00000081479","Gene description":"LDL receptor related protein 2","Uniprot":["P98164"],"Chromosome":"2","Position":"169127109-169362534","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Endocytosis","Hearing","Neurogenesis","Transport"],"Molecular function":["Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"70.5","kidney":"34.8","parathyroid gland":"44.7","retina":"29.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"87.6","Cytotrophoblasts":"63.2","Oligodendrocytes":"300.1","Proximal tubular cells":"283.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"29.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"AF22":"39.4","CACO-2":"64.2"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005980","HPA064792"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"74000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Vesicles","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA005980":"AB_1079278","HPA064792":"AB_2685353"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.43e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.5","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"5.5","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"23.4","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"9.6","Tissue RNA - cerebellum [nTPM]":"18.9","Tissue RNA - cerebral cortex [nTPM]":"13.5","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"7.5","Tissue RNA - hypothalamus [nTPM]":"14.6","Tissue RNA - kidney [nTPM]":"34.8","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"1.2","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"30.5","Tissue RNA - midbrain [nTPM]":"17.5","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"44.7","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"7.5","Tissue RNA - pons [nTPM]":"31.9","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"29.3","Tissue RNA - salivary gland [nTPM]":"0.9","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"14.5","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"18.7","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"17.3","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"70.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"39.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"64.2","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.4","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"4.6","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"1.6","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.7","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"3.9","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"5.5","Brain RNA - basal ganglia [nTPM]":"23.4","Brain RNA - cerebellum [nTPM]":"18.9","Brain RNA - cerebral cortex [nTPM]":"13.5","Brain RNA - hippocampal formation [nTPM]":"7.5","Brain RNA - hypothalamus [nTPM]":"14.6","Brain RNA - medulla oblongata [nTPM]":"30.5","Brain RNA - midbrain [nTPM]":"17.5","Brain RNA - pons [nTPM]":"31.9","Brain RNA - spinal cord [nTPM]":"14.5","Brain RNA - thalamus [nTPM]":"18.7","Brain RNA - white matter [nTPM]":"70.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"43.7","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"3.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"2.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"2.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"87.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"63.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.2","Single Cell Type RNA - Fibroblasts [nTPM]":"1.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"2.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"33.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"300.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"283.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.1","Single Cell Type RNA - T-cells [nTPM]":"1.7","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"LRP4","Gene synonym":["CLSS","LRP-4","MEGF7","SOST2"],"Ensembl":"ENSG00000134569","Gene description":"LDL receptor related protein 4","Uniprot":["O75096"],"Chromosome":"11","Position":"46856717-46918642","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Differentiation","Endocytosis","Wnt signaling pathway"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"46.7","skin 1":"31.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"123.1","Cone photoreceptor cells":"41.7","Distal enterocytes":"31.1","Oligodendrocyte precursor cells":"137.2","Oligodendrocytes":"31.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"colorectal cancer":"12.2","endometrial cancer":"8.6","glioma":"13.2","testis cancer":"15.6","thyroid cancer":"28.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"21.3","SuSa":"16.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011934","HPA012300"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Nucleoli","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":["Nucleoplasm","Nucleoli","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA011934":"AB_1853286","HPA012300":"AB_1853288"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.73e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.90e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.79e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.7","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"23.3","Tissue RNA - appendix [nTPM]":"0.9","Tissue RNA - basal ganglia [nTPM]":"30.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.5","Tissue RNA - cerebellum [nTPM]":"19.1","Tissue RNA - cerebral cortex [nTPM]":"21.3","Tissue RNA - cervix [nTPM]":"2.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"4.8","Tissue RNA - duodenum [nTPM]":"3.4","Tissue RNA - endometrium 1 [nTPM]":"1.6","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"1.8","Tissue RNA - fallopian tube [nTPM]":"1.4","Tissue RNA - gallbladder [nTPM]":"2.0","Tissue RNA - heart muscle [nTPM]":"6.9","Tissue RNA - hippocampal formation [nTPM]":"24.2","Tissue RNA - hypothalamus [nTPM]":"16.0","Tissue RNA - kidney [nTPM]":"0.7","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"2.9","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"46.7","Tissue RNA - midbrain [nTPM]":"23.0","Tissue RNA - ovary [nTPM]":"4.6","Tissue RNA - pancreas [nTPM]":"2.2","Tissue RNA - parathyroid gland [nTPM]":"5.6","Tissue RNA - pituitary gland [nTPM]":"2.6","Tissue RNA - placenta [nTPM]":"2.6","Tissue RNA - pons [nTPM]":"19.8","Tissue RNA - prostate [nTPM]":"2.1","Tissue RNA - rectum [nTPM]":"3.4","Tissue RNA - retina [nTPM]":"7.9","Tissue RNA - salivary gland [nTPM]":"1.7","Tissue RNA - seminal vesicle [nTPM]":"2.3","Tissue RNA - skeletal muscle [nTPM]":"4.4","Tissue RNA - skin 1 [nTPM]":"31.6","Tissue RNA - small intestine [nTPM]":"4.9","Tissue RNA - smooth muscle [nTPM]":"1.5","Tissue RNA - spinal cord [nTPM]":"21.3","Tissue RNA - spleen [nTPM]":"3.9","Tissue RNA - stomach 1 [nTPM]":"7.8","Tissue RNA - testis [nTPM]":"1.1","Tissue RNA - thalamus [nTPM]":"30.9","Tissue RNA - thymus [nTPM]":"1.5","Tissue RNA - thyroid gland [nTPM]":"2.4","Tissue RNA - tongue [nTPM]":"7.7","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"0.9","Tissue RNA - vagina [nTPM]":"1.4","Tissue RNA - white matter [nTPM]":"25.6","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"9.6","Cell RNA - AF22 [nTPM]":"21.3","Cell RNA - AN3-CA [nTPM]":"6.5","Cell RNA - ASC diff [nTPM]":"13.4","Cell RNA - ASC TERT1 [nTPM]":"3.7","Cell RNA - BEWO [nTPM]":"4.9","Cell RNA - BJ [nTPM]":"1.0","Cell RNA - BJ hTERT+ [nTPM]":"1.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.2","Cell RNA - CACO-2 [nTPM]":"2.8","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.4","Cell RNA - fHDF\/TERT166 [nTPM]":"11.4","Cell RNA - GAMG [nTPM]":"3.1","Cell RNA - HaCaT [nTPM]":"3.9","Cell RNA - HAP1 [nTPM]":"12.0","Cell RNA - HBEC3-KT [nTPM]":"7.5","Cell RNA - HBF TERT88 [nTPM]":"2.2","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"10.3","Cell RNA - HEL [nTPM]":"1.0","Cell RNA - HeLa [nTPM]":"3.8","Cell RNA - Hep G2 [nTPM]":"6.8","Cell RNA - HHSteC [nTPM]":"2.8","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"1.9","Cell RNA - HSkMC [nTPM]":"4.5","Cell RNA - hTCEpi [nTPM]":"4.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.4","Cell RNA - hTERT-HME1 [nTPM]":"1.1","Cell RNA - hTERT-RPE1 [nTPM]":"2.5","Cell RNA - HUVEC TERT2 [nTPM]":"2.5","Cell RNA - JURKAT [nTPM]":"2.6","Cell RNA - K-562 [nTPM]":"0.9","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"1.6","Cell RNA - MCF7 [nTPM]":"0.8","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"11.9","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.9","Cell RNA - REH [nTPM]":"1.6","Cell RNA - RH-30 [nTPM]":"7.3","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.3","Cell RNA - RT4 [nTPM]":"2.8","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"14.2","Cell RNA - SiHa [nTPM]":"1.2","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"3.4","Cell RNA - SuSa [nTPM]":"16.2","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"5.7","Cell RNA - U-2 OS [nTPM]":"3.5","Cell RNA - U-2197 [nTPM]":"6.5","Cell RNA - U-251 MG [nTPM]":"2.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"4.3","Cell RNA - U-937 [nTPM]":"0.7","Cell RNA - WM-115 [nTPM]":"2.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"23.3","Brain RNA - basal ganglia [nTPM]":"30.5","Brain RNA - cerebellum [nTPM]":"19.1","Brain RNA - cerebral cortex [nTPM]":"21.3","Brain RNA - hippocampal formation [nTPM]":"24.2","Brain RNA - hypothalamus [nTPM]":"16.0","Brain RNA - medulla oblongata [nTPM]":"46.7","Brain RNA - midbrain [nTPM]":"23.0","Brain RNA - pons [nTPM]":"19.8","Brain RNA - spinal cord [nTPM]":"21.3","Brain RNA - thalamus [nTPM]":"30.9","Brain RNA - white matter [nTPM]":"25.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.9","Single Cell Type RNA - Astrocytes [nTPM]":"123.1","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"31.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.7","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"5.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.4","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"1.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"9.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"137.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"31.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"3.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"8.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"LRRC8A","Gene synonym":["FLJ10337","KIAA1437","LRRC8","SWELL1"],"Ensembl":"ENSG00000136802","Gene description":"Leucine rich repeat containing 8 VRAC subunit A","Uniprot":["Q8IWT6"],"Chromosome":"9","Position":"128882133-128918039","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Differentiation","Ion transport","Spermatogenesis","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"192.0","Prostatic glandular cells":"207.0","Urothelial cells":"328.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"163.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.83e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.27e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Tissue RNA - adipose tissue [nTPM]":"31.4","Tissue RNA - adrenal gland [nTPM]":"17.4","Tissue RNA - amygdala [nTPM]":"68.2","Tissue RNA - appendix [nTPM]":"16.2","Tissue RNA - basal ganglia [nTPM]":"69.4","Tissue RNA - bone marrow [nTPM]":"17.3","Tissue RNA - breast [nTPM]":"27.3","Tissue RNA - cerebellum [nTPM]":"69.4","Tissue RNA - cerebral cortex [nTPM]":"77.1","Tissue RNA - cervix [nTPM]":"30.8","Tissue RNA - choroid plexus [nTPM]":"44.6","Tissue RNA - colon [nTPM]":"31.4","Tissue RNA - duodenum [nTPM]":"9.7","Tissue RNA - endometrium 1 [nTPM]":"36.3","Tissue RNA - epididymis [nTPM]":"7.3","Tissue RNA - esophagus [nTPM]":"71.7","Tissue RNA - fallopian tube [nTPM]":"23.5","Tissue RNA - gallbladder [nTPM]":"23.3","Tissue RNA - heart muscle [nTPM]":"32.0","Tissue RNA - hippocampal formation [nTPM]":"57.2","Tissue RNA - hypothalamus [nTPM]":"67.9","Tissue RNA - kidney [nTPM]":"18.2","Tissue RNA - liver [nTPM]":"28.9","Tissue RNA - lung [nTPM]":"42.4","Tissue RNA - lymph node [nTPM]":"9.3","Tissue RNA - medulla oblongata [nTPM]":"76.7","Tissue RNA - midbrain [nTPM]":"77.2","Tissue RNA - ovary [nTPM]":"18.8","Tissue RNA - pancreas [nTPM]":"21.2","Tissue RNA - parathyroid gland [nTPM]":"32.4","Tissue RNA - pituitary gland [nTPM]":"13.7","Tissue RNA - placenta [nTPM]":"23.1","Tissue RNA - pons [nTPM]":"67.9","Tissue RNA - prostate [nTPM]":"29.3","Tissue RNA - rectum [nTPM]":"8.5","Tissue RNA - retina [nTPM]":"13.4","Tissue RNA - salivary gland [nTPM]":"28.1","Tissue RNA - seminal vesicle [nTPM]":"25.5","Tissue RNA - skeletal muscle [nTPM]":"13.9","Tissue RNA - skin 1 [nTPM]":"35.2","Tissue RNA - small intestine [nTPM]":"17.3","Tissue RNA - smooth muscle [nTPM]":"29.1","Tissue RNA - spinal cord [nTPM]":"63.9","Tissue RNA - spleen [nTPM]":"16.2","Tissue RNA - stomach 1 [nTPM]":"25.0","Tissue RNA - testis [nTPM]":"11.8","Tissue RNA - thalamus [nTPM]":"82.6","Tissue RNA - thymus [nTPM]":"9.9","Tissue RNA - thyroid gland [nTPM]":"25.6","Tissue RNA - tongue [nTPM]":"18.4","Tissue RNA - tonsil [nTPM]":"10.1","Tissue RNA - urinary bladder [nTPM]":"32.7","Tissue RNA - vagina [nTPM]":"44.2","Tissue RNA - white matter [nTPM]":"52.4","Cell RNA - A-431 [nTPM]":"35.1","Cell RNA - A549 [nTPM]":"54.2","Cell RNA - AF22 [nTPM]":"32.0","Cell RNA - AN3-CA [nTPM]":"27.5","Cell RNA - ASC diff [nTPM]":"73.6","Cell RNA - ASC TERT1 [nTPM]":"28.3","Cell RNA - BEWO [nTPM]":"40.4","Cell RNA - BJ [nTPM]":"39.8","Cell RNA - BJ hTERT+ [nTPM]":"26.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.1","Cell RNA - CACO-2 [nTPM]":"24.1","Cell RNA - CAPAN-2 [nTPM]":"73.2","Cell RNA - Daudi [nTPM]":"12.8","Cell RNA - EFO-21 [nTPM]":"43.6","Cell RNA - fHDF\/TERT166 [nTPM]":"43.3","Cell RNA - GAMG [nTPM]":"30.1","Cell RNA - HaCaT [nTPM]":"163.8","Cell RNA - HAP1 [nTPM]":"19.9","Cell RNA - HBEC3-KT [nTPM]":"87.5","Cell RNA - HBF TERT88 [nTPM]":"11.3","Cell RNA - HDLM-2 [nTPM]":"13.1","Cell RNA - HEK 293 [nTPM]":"16.4","Cell RNA - HEL [nTPM]":"11.5","Cell RNA - HeLa [nTPM]":"33.4","Cell RNA - Hep G2 [nTPM]":"29.2","Cell RNA - HHSteC [nTPM]":"49.8","Cell RNA - HL-60 [nTPM]":"13.8","Cell RNA - HMC-1 [nTPM]":"20.3","Cell RNA - HSkMC [nTPM]":"22.1","Cell RNA - hTCEpi [nTPM]":"60.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"42.7","Cell RNA - hTERT-HME1 [nTPM]":"50.8","Cell RNA - hTERT-RPE1 [nTPM]":"48.6","Cell RNA - HUVEC TERT2 [nTPM]":"84.1","Cell RNA - JURKAT [nTPM]":"17.5","Cell RNA - K-562 [nTPM]":"25.8","Cell RNA - Karpas-707 [nTPM]":"12.4","Cell RNA - LHCN-M2 [nTPM]":"31.8","Cell RNA - MCF7 [nTPM]":"30.3","Cell RNA - MOLT-4 [nTPM]":"15.6","Cell RNA - NB-4 [nTPM]":"13.2","Cell RNA - NTERA-2 [nTPM]":"95.9","Cell RNA - OE19 [nTPM]":"58.3","Cell RNA - PC-3 [nTPM]":"58.4","Cell RNA - REH [nTPM]":"21.4","Cell RNA - RH-30 [nTPM]":"37.0","Cell RNA - RPMI-8226 [nTPM]":"20.6","Cell RNA - RPTEC TERT1 [nTPM]":"37.9","Cell RNA - RT4 [nTPM]":"17.3","Cell RNA - SCLC-21H [nTPM]":"19.2","Cell RNA - SH-SY5Y [nTPM]":"39.9","Cell RNA - SiHa [nTPM]":"44.4","Cell RNA - SK-BR-3 [nTPM]":"27.3","Cell RNA - SK-MEL-30 [nTPM]":"15.8","Cell RNA - SuSa [nTPM]":"23.9","Cell RNA - T-47d [nTPM]":"19.9","Cell RNA - THP-1 [nTPM]":"10.2","Cell RNA - TIME [nTPM]":"149.4","Cell RNA - U-138 MG [nTPM]":"69.9","Cell RNA - U-2 OS [nTPM]":"30.2","Cell RNA - U-2197 [nTPM]":"29.9","Cell RNA - U-251 MG [nTPM]":"58.8","Cell RNA - U-266\/70 [nTPM]":"14.4","Cell RNA - U-266\/84 [nTPM]":"36.5","Cell RNA - U-698 [nTPM]":"15.5","Cell RNA - U-87 MG [nTPM]":"38.7","Cell RNA - U-937 [nTPM]":"10.3","Cell RNA - WM-115 [nTPM]":"41.3","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"0.7","Blood RNA - eosinophil [nTPM]":"1.9","Blood RNA - gdT-cell [nTPM]":"3.9","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"1.8","Blood RNA - memory B-cell [nTPM]":"1.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.9","Blood RNA - memory CD8 T-cell [nTPM]":"2.5","Blood RNA - myeloid DC [nTPM]":"1.0","Blood RNA - naive B-cell [nTPM]":"0.9","Blood RNA - naive CD4 T-cell [nTPM]":"1.9","Blood RNA - naive CD8 T-cell [nTPM]":"1.8","Blood RNA - neutrophil [nTPM]":"1.4","Blood RNA - NK-cell [nTPM]":"3.5","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"1.6","Blood RNA - T-reg [nTPM]":"3.5","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"68.2","Brain RNA - basal ganglia [nTPM]":"69.4","Brain RNA - cerebellum [nTPM]":"69.4","Brain RNA - cerebral cortex [nTPM]":"77.1","Brain RNA - hippocampal formation [nTPM]":"57.2","Brain RNA - hypothalamus [nTPM]":"67.9","Brain RNA - medulla oblongata [nTPM]":"76.7","Brain RNA - midbrain [nTPM]":"77.2","Brain RNA - pons [nTPM]":"67.9","Brain RNA - spinal cord [nTPM]":"63.9","Brain RNA - thalamus [nTPM]":"82.6","Brain RNA - white matter [nTPM]":"52.4","Single Cell Type RNA - Adipocytes [nTPM]":"98.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.6","Single Cell Type RNA - Astrocytes [nTPM]":"57.1","Single Cell Type RNA - B-cells [nTPM]":"7.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"105.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"192.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"91.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"113.3","Single Cell Type RNA - Bipolar cells [nTPM]":"13.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"38.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"29.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"31.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"73.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.8","Single Cell Type RNA - dendritic cells [nTPM]":"17.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"31.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"28.9","Single Cell Type RNA - Early spermatids [nTPM]":"6.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"50.5","Single Cell Type RNA - Endothelial cells [nTPM]":"57.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.1","Single Cell Type RNA - Erythroid cells [nTPM]":"13.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.6","Single Cell Type RNA - Fibroblasts [nTPM]":"27.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"24.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"47.0","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"35.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"55.6","Single Cell Type RNA - Hepatocytes [nTPM]":"16.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.1","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.7","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"5.0","Single Cell Type RNA - Langerhans cells [nTPM]":"17.4","Single Cell Type RNA - Late spermatids [nTPM]":"4.5","Single Cell Type RNA - Leydig cells [nTPM]":"23.0","Single Cell Type RNA - Macrophages [nTPM]":"9.9","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"5.1","Single Cell Type RNA - Muller glia cells [nTPM]":"41.3","Single Cell Type RNA - NK-cells [nTPM]":"36.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"78.1","Single Cell Type RNA - Paneth cells [nTPM]":"23.0","Single Cell Type RNA - Peritubular cells [nTPM]":"44.4","Single Cell Type RNA - Plasma cells [nTPM]":"13.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"207.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.2","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"38.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"35.2","Single Cell Type RNA - Spermatocytes [nTPM]":"3.2","Single Cell Type RNA - Spermatogonia [nTPM]":"8.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"91.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"145.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.8","Single Cell Type RNA - T-cells [nTPM]":"15.5","Single Cell Type RNA - Theca cells [nTPM]":"9.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.5","Single Cell Type RNA - Urothelial cells [nTPM]":"328.5"},{"Gene":"LRRK2","Gene synonym":["DKFZp434H2111","FLJ45829","PARK8","RIPK7","ROCO2"],"Ensembl":"ENSG00000188906","Gene description":"Leucine rich repeat kinase 2","Uniprot":["Q5S007"],"Chromosome":"12","Position":"40196744-40369285","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Autophagy","Differentiation"],"Molecular function":["GTPase activation","Hydrolase","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"lung":"52.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"502.2","Excitatory neurons":"92.0","monocytes":"133.1","Oligodendrocyte precursor cells":"256.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"17.1","thyroid cancer":"22.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"neutrophil":"58.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"58.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"4.6","ASC TERT1":"5.6","BJ hTERT+":"3.2","RPTEC TERT1":"7.8","T-47d":"3.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014293","CAB037160"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 11: Alveolar cells - Smell perception","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB037160":"AB_1840989","HPA014293":"AB_1853353"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.02e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-3"},"Tissue RNA - adipose tissue [nTPM]":"4.8","Tissue RNA - adrenal gland [nTPM]":"3.1","Tissue RNA - amygdala [nTPM]":"1.1","Tissue RNA - appendix [nTPM]":"10.1","Tissue RNA - basal ganglia [nTPM]":"1.9","Tissue RNA - bone marrow [nTPM]":"9.0","Tissue RNA - breast [nTPM]":"2.6","Tissue RNA - cerebellum [nTPM]":"0.9","Tissue RNA - cerebral cortex [nTPM]":"2.1","Tissue RNA - cervix [nTPM]":"5.1","Tissue RNA - choroid plexus [nTPM]":"1.2","Tissue RNA - colon [nTPM]":"4.3","Tissue RNA - duodenum [nTPM]":"0.6","Tissue RNA - endometrium 1 [nTPM]":"4.8","Tissue RNA - epididymis [nTPM]":"1.9","Tissue RNA - esophagus [nTPM]":"7.0","Tissue RNA - fallopian tube [nTPM]":"4.1","Tissue RNA - gallbladder [nTPM]":"6.2","Tissue RNA - heart muscle [nTPM]":"3.9","Tissue RNA - hippocampal formation [nTPM]":"1.3","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"10.9","Tissue RNA - liver [nTPM]":"5.6","Tissue RNA - lung [nTPM]":"52.4","Tissue RNA - lymph node [nTPM]":"6.8","Tissue RNA - medulla oblongata [nTPM]":"1.7","Tissue RNA - midbrain [nTPM]":"1.1","Tissue RNA - ovary [nTPM]":"5.4","Tissue RNA - pancreas [nTPM]":"3.6","Tissue RNA - parathyroid gland [nTPM]":"8.4","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"1.2","Tissue RNA - pons [nTPM]":"1.4","Tissue RNA - prostate [nTPM]":"2.6","Tissue RNA - rectum [nTPM]":"1.8","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"3.5","Tissue RNA - seminal vesicle [nTPM]":"2.0","Tissue RNA - skeletal muscle [nTPM]":"5.5","Tissue RNA - skin 1 [nTPM]":"2.1","Tissue RNA - small intestine [nTPM]":"3.6","Tissue RNA - smooth muscle [nTPM]":"4.0","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"10.8","Tissue RNA - stomach 1 [nTPM]":"2.1","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"2.5","Tissue RNA - thyroid gland [nTPM]":"2.9","Tissue RNA - tongue [nTPM]":"7.9","Tissue RNA - tonsil [nTPM]":"5.4","Tissue RNA - urinary bladder [nTPM]":"4.5","Tissue RNA - vagina [nTPM]":"5.5","Tissue RNA - white matter [nTPM]":"1.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"4.6","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"2.3","Cell RNA - ASC TERT1 [nTPM]":"5.6","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"1.3","Cell RNA - BJ hTERT+ [nTPM]":"3.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.8","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.6","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"2.1","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"2.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.4","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"7.8","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"2.7","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"3.1","Cell RNA - THP-1 [nTPM]":"1.5","Cell RNA - TIME [nTPM]":"1.0","Cell RNA - U-138 MG [nTPM]":"0.4","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.6","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"7.2","Blood RNA - eosinophil [nTPM]":"2.2","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"5.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"2.1","Blood RNA - naive B-cell [nTPM]":"1.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"58.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"6.9","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.3","Brain RNA - amygdala [nTPM]":"1.1","Brain RNA - basal ganglia [nTPM]":"1.9","Brain RNA - cerebellum [nTPM]":"0.9","Brain RNA - cerebral cortex [nTPM]":"2.1","Brain RNA - hippocampal formation [nTPM]":"1.3","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"1.7","Brain RNA - midbrain [nTPM]":"1.1","Brain RNA - pons [nTPM]":"1.4","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"1.9","Single Cell Type RNA - Adipocytes [nTPM]":"7.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"502.2","Single Cell Type RNA - Astrocytes [nTPM]":"17.3","Single Cell Type RNA - B-cells [nTPM]":"29.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"8.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"17.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.6","Single Cell Type RNA - Endothelial cells [nTPM]":"7.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"92.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"16.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"13.9","Single Cell Type RNA - Granulosa cells [nTPM]":"2.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.2","Single Cell Type RNA - Hepatocytes [nTPM]":"8.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.6","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"28.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"55.8","Single Cell Type RNA - Langerhans cells [nTPM]":"8.7","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"19.0","Single Cell Type RNA - Macrophages [nTPM]":"52.2","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"73.1","Single Cell Type RNA - monocytes [nTPM]":"133.1","Single Cell Type RNA - Muller glia cells [nTPM]":"8.6","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"256.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.8","Single Cell Type RNA - Paneth cells [nTPM]":"1.1","Single Cell Type RNA - Peritubular cells [nTPM]":"12.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"3.4","Single Cell Type RNA - Theca cells [nTPM]":"11.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"LRSAM1","Gene synonym":["CMT2P","FLJ31641","RIFLE","TAL"],"Ensembl":"ENSG00000148356","Gene description":"Leucine rich repeat and sterile alpha motif containing 1","Uniprot":["Q6UWE0"],"Chromosome":"9","Position":"127451489-127503499","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Autophagy","Protein transport","Transport","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"32.0","Excitatory neurons":"28.6","Inhibitory neurons":"26.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021403","HPA021844","CAB037304"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB037304":"AB_2138198","HPA021403":"AB_1853366","HPA021844":"AB_1853368"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.78e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.72e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.2","Tissue RNA - adrenal gland [nTPM]":"9.8","Tissue RNA - amygdala [nTPM]":"8.6","Tissue RNA - appendix [nTPM]":"3.4","Tissue RNA - basal ganglia [nTPM]":"8.6","Tissue RNA - bone marrow [nTPM]":"2.0","Tissue RNA - breast [nTPM]":"7.3","Tissue RNA - cerebellum [nTPM]":"7.3","Tissue RNA - cerebral cortex [nTPM]":"12.5","Tissue RNA - cervix [nTPM]":"10.7","Tissue RNA - choroid plexus [nTPM]":"5.2","Tissue RNA - colon [nTPM]":"16.5","Tissue RNA - duodenum [nTPM]":"3.4","Tissue RNA - endometrium 1 [nTPM]":"9.0","Tissue RNA - epididymis [nTPM]":"5.9","Tissue RNA - esophagus [nTPM]":"8.7","Tissue RNA - fallopian tube [nTPM]":"7.8","Tissue RNA - gallbladder [nTPM]":"3.9","Tissue RNA - heart muscle [nTPM]":"17.3","Tissue RNA - hippocampal formation [nTPM]":"8.8","Tissue RNA - hypothalamus [nTPM]":"8.8","Tissue RNA - kidney [nTPM]":"9.0","Tissue RNA - liver [nTPM]":"8.8","Tissue RNA - lung [nTPM]":"7.4","Tissue RNA - lymph node [nTPM]":"4.5","Tissue RNA - medulla oblongata [nTPM]":"11.1","Tissue RNA - midbrain [nTPM]":"7.6","Tissue RNA - ovary [nTPM]":"10.7","Tissue RNA - pancreas [nTPM]":"5.7","Tissue RNA - parathyroid gland [nTPM]":"6.9","Tissue RNA - pituitary gland [nTPM]":"9.0","Tissue RNA - placenta [nTPM]":"3.4","Tissue RNA - pons [nTPM]":"11.4","Tissue RNA - prostate [nTPM]":"9.1","Tissue RNA - rectum [nTPM]":"2.6","Tissue RNA - retina [nTPM]":"2.3","Tissue RNA - salivary gland [nTPM]":"7.5","Tissue RNA - seminal vesicle [nTPM]":"5.6","Tissue RNA - skeletal muscle [nTPM]":"13.5","Tissue RNA - skin 1 [nTPM]":"21.2","Tissue RNA - small intestine [nTPM]":"9.1","Tissue RNA - smooth muscle [nTPM]":"5.0","Tissue RNA - spinal cord [nTPM]":"7.0","Tissue RNA - spleen [nTPM]":"9.5","Tissue RNA - stomach 1 [nTPM]":"9.5","Tissue RNA - testis [nTPM]":"4.3","Tissue RNA - thalamus [nTPM]":"7.9","Tissue RNA - thymus [nTPM]":"3.4","Tissue RNA - thyroid gland [nTPM]":"8.8","Tissue RNA - tongue [nTPM]":"7.2","Tissue RNA - tonsil [nTPM]":"3.2","Tissue RNA - urinary bladder [nTPM]":"12.3","Tissue RNA - vagina [nTPM]":"10.2","Tissue RNA - white matter [nTPM]":"9.0","Cell RNA - A-431 [nTPM]":"5.7","Cell RNA - A549 [nTPM]":"10.8","Cell RNA - AF22 [nTPM]":"4.8","Cell RNA - AN3-CA [nTPM]":"10.7","Cell RNA - ASC diff [nTPM]":"9.8","Cell RNA - ASC TERT1 [nTPM]":"9.1","Cell RNA - BEWO [nTPM]":"8.3","Cell RNA - BJ [nTPM]":"5.3","Cell RNA - BJ hTERT+ [nTPM]":"8.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.6","Cell RNA - CACO-2 [nTPM]":"8.9","Cell RNA - CAPAN-2 [nTPM]":"5.9","Cell RNA - Daudi [nTPM]":"9.8","Cell RNA - EFO-21 [nTPM]":"5.9","Cell RNA - fHDF\/TERT166 [nTPM]":"9.9","Cell RNA - GAMG [nTPM]":"3.6","Cell RNA - HaCaT [nTPM]":"18.7","Cell RNA - HAP1 [nTPM]":"7.8","Cell RNA - HBEC3-KT [nTPM]":"13.3","Cell RNA - HBF TERT88 [nTPM]":"3.8","Cell RNA - HDLM-2 [nTPM]":"11.5","Cell RNA - HEK 293 [nTPM]":"5.3","Cell RNA - HEL [nTPM]":"5.2","Cell RNA - HeLa [nTPM]":"9.0","Cell RNA - Hep G2 [nTPM]":"10.2","Cell RNA - HHSteC [nTPM]":"9.4","Cell RNA - HL-60 [nTPM]":"6.2","Cell RNA - HMC-1 [nTPM]":"7.3","Cell RNA - HSkMC [nTPM]":"6.1","Cell RNA - hTCEpi [nTPM]":"7.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.1","Cell RNA - hTERT-HME1 [nTPM]":"12.2","Cell RNA - hTERT-RPE1 [nTPM]":"10.7","Cell RNA - HUVEC TERT2 [nTPM]":"11.2","Cell RNA - JURKAT [nTPM]":"7.6","Cell RNA - K-562 [nTPM]":"4.8","Cell RNA - Karpas-707 [nTPM]":"7.6","Cell RNA - LHCN-M2 [nTPM]":"4.5","Cell RNA - MCF7 [nTPM]":"17.6","Cell RNA - MOLT-4 [nTPM]":"3.9","Cell RNA - NB-4 [nTPM]":"4.5","Cell RNA - NTERA-2 [nTPM]":"4.7","Cell RNA - OE19 [nTPM]":"17.4","Cell RNA - PC-3 [nTPM]":"9.3","Cell RNA - REH [nTPM]":"7.1","Cell RNA - RH-30 [nTPM]":"5.6","Cell RNA - RPMI-8226 [nTPM]":"18.4","Cell RNA - RPTEC TERT1 [nTPM]":"11.5","Cell RNA - RT4 [nTPM]":"5.1","Cell RNA - SCLC-21H [nTPM]":"9.8","Cell RNA - SH-SY5Y [nTPM]":"9.2","Cell RNA - SiHa [nTPM]":"4.1","Cell RNA - SK-BR-3 [nTPM]":"12.6","Cell RNA - SK-MEL-30 [nTPM]":"8.8","Cell RNA - SuSa [nTPM]":"4.3","Cell RNA - T-47d [nTPM]":"26.5","Cell RNA - THP-1 [nTPM]":"3.2","Cell RNA - TIME [nTPM]":"10.2","Cell RNA - U-138 MG [nTPM]":"4.6","Cell RNA - U-2 OS [nTPM]":"5.6","Cell RNA - U-2197 [nTPM]":"4.2","Cell RNA - U-251 MG [nTPM]":"2.5","Cell RNA - U-266\/70 [nTPM]":"6.2","Cell RNA - U-266\/84 [nTPM]":"7.9","Cell RNA - U-698 [nTPM]":"1.1","Cell RNA - U-87 MG [nTPM]":"9.1","Cell RNA - U-937 [nTPM]":"4.5","Cell RNA - WM-115 [nTPM]":"2.6","Blood RNA - basophil [nTPM]":"18.5","Blood RNA - classical monocyte [nTPM]":"4.8","Blood RNA - eosinophil [nTPM]":"21.3","Blood RNA - gdT-cell [nTPM]":"3.7","Blood RNA - intermediate monocyte [nTPM]":"6.5","Blood RNA - MAIT T-cell [nTPM]":"4.7","Blood RNA - memory B-cell [nTPM]":"3.7","Blood RNA - memory CD4 T-cell [nTPM]":"2.8","Blood RNA - memory CD8 T-cell [nTPM]":"3.5","Blood RNA - myeloid DC [nTPM]":"6.1","Blood RNA - naive B-cell [nTPM]":"2.7","Blood RNA - naive CD4 T-cell [nTPM]":"1.1","Blood RNA - naive CD8 T-cell [nTPM]":"1.4","Blood RNA - neutrophil [nTPM]":"4.0","Blood RNA - NK-cell [nTPM]":"1.3","Blood RNA - non-classical monocyte [nTPM]":"6.8","Blood RNA - plasmacytoid DC [nTPM]":"3.6","Blood RNA - T-reg [nTPM]":"2.3","Blood RNA - total PBMC [nTPM]":"3.8","Brain RNA - amygdala [nTPM]":"8.6","Brain RNA - basal ganglia [nTPM]":"8.6","Brain RNA - cerebellum [nTPM]":"7.3","Brain RNA - cerebral cortex [nTPM]":"12.5","Brain RNA - hippocampal formation [nTPM]":"8.8","Brain RNA - hypothalamus [nTPM]":"8.8","Brain RNA - medulla oblongata [nTPM]":"11.1","Brain RNA - midbrain [nTPM]":"7.6","Brain RNA - pons [nTPM]":"11.4","Brain RNA - spinal cord [nTPM]":"7.0","Brain RNA - thalamus [nTPM]":"7.9","Brain RNA - white matter [nTPM]":"9.0","Single Cell Type RNA - Adipocytes [nTPM]":"5.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.9","Single Cell Type RNA - Astrocytes [nTPM]":"32.0","Single Cell Type RNA - B-cells [nTPM]":"5.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"6.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"20.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"7.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.0","Single Cell Type RNA - dendritic cells [nTPM]":"5.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.7","Single Cell Type RNA - Endothelial cells [nTPM]":"4.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"2.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"28.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.1","Single Cell Type RNA - Fibroblasts [nTPM]":"4.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.6","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"6.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"7.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.3","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"26.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.8","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.6","Single Cell Type RNA - Langerhans cells [nTPM]":"3.7","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"7.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"7.4","Single Cell Type RNA - Muller glia cells [nTPM]":"4.7","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.7","Single Cell Type RNA - Paneth cells [nTPM]":"5.0","Single Cell Type RNA - Peritubular cells [nTPM]":"5.3","Single Cell Type RNA - Plasma cells [nTPM]":"3.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.0","Single Cell Type RNA - Spermatocytes [nTPM]":"5.7","Single Cell Type RNA - Spermatogonia [nTPM]":"3.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.0","Single Cell Type RNA - T-cells [nTPM]":"5.6","Single Cell Type RNA - Theca cells [nTPM]":"3.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.8","Single Cell Type RNA - Urothelial cells [nTPM]":"3.3"},{"Gene":"LSS","Gene synonym":["OSC"],"Ensembl":"ENSG00000160285","Gene description":"Lanosterol synthase","Uniprot":["P48449"],"Chromosome":"21","Position":"46188141-46228824","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis"],"Molecular function":["Isomerase"],"Disease involvement":["Cataract","Disease variant","Hypotrichosis","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"132.0","Oligodendrocytes":"158.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"GAMG":"234.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032060","HPA032062","CAB034116"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB034116":"AB_2138611","HPA032060":"AB_10671085","HPA032062":"AB_2674134"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.80e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.07e-4"},"Tissue RNA - adipose tissue [nTPM]":"29.3","Tissue RNA - adrenal gland [nTPM]":"38.9","Tissue RNA - amygdala [nTPM]":"20.0","Tissue RNA - appendix [nTPM]":"10.8","Tissue RNA - basal ganglia [nTPM]":"30.8","Tissue RNA - bone marrow [nTPM]":"5.7","Tissue RNA - breast [nTPM]":"22.3","Tissue RNA - cerebellum [nTPM]":"38.9","Tissue RNA - cerebral cortex [nTPM]":"33.5","Tissue RNA - cervix [nTPM]":"20.8","Tissue RNA - choroid plexus [nTPM]":"7.1","Tissue RNA - colon [nTPM]":"22.9","Tissue RNA - duodenum [nTPM]":"28.5","Tissue RNA - endometrium 1 [nTPM]":"26.6","Tissue RNA - epididymis [nTPM]":"12.1","Tissue RNA - esophagus [nTPM]":"39.7","Tissue RNA - fallopian tube [nTPM]":"18.0","Tissue RNA - gallbladder [nTPM]":"9.0","Tissue RNA - heart muscle [nTPM]":"25.1","Tissue RNA - hippocampal formation [nTPM]":"15.7","Tissue RNA - hypothalamus [nTPM]":"26.2","Tissue RNA - kidney [nTPM]":"10.7","Tissue RNA - liver [nTPM]":"54.8","Tissue RNA - lung [nTPM]":"24.1","Tissue RNA - lymph node [nTPM]":"9.4","Tissue RNA - medulla oblongata [nTPM]":"62.3","Tissue RNA - midbrain [nTPM]":"40.7","Tissue RNA - ovary [nTPM]":"30.3","Tissue RNA - pancreas [nTPM]":"19.4","Tissue RNA - parathyroid gland [nTPM]":"12.2","Tissue RNA - pituitary gland [nTPM]":"25.9","Tissue RNA - placenta [nTPM]":"8.0","Tissue RNA - pons [nTPM]":"65.7","Tissue RNA - prostate [nTPM]":"24.0","Tissue RNA - rectum [nTPM]":"10.7","Tissue RNA - retina [nTPM]":"6.8","Tissue RNA - salivary gland [nTPM]":"16.1","Tissue RNA - seminal vesicle [nTPM]":"12.4","Tissue RNA - skeletal muscle [nTPM]":"29.0","Tissue RNA - skin 1 [nTPM]":"27.6","Tissue RNA - small intestine [nTPM]":"17.4","Tissue RNA - smooth muscle [nTPM]":"12.2","Tissue RNA - spinal cord [nTPM]":"28.4","Tissue RNA - spleen [nTPM]":"7.6","Tissue RNA - stomach 1 [nTPM]":"23.3","Tissue RNA - testis [nTPM]":"17.5","Tissue RNA - thalamus [nTPM]":"40.4","Tissue RNA - thymus [nTPM]":"12.3","Tissue RNA - thyroid gland [nTPM]":"10.2","Tissue RNA - tongue [nTPM]":"19.5","Tissue RNA - tonsil [nTPM]":"8.0","Tissue RNA - urinary bladder [nTPM]":"20.2","Tissue RNA - vagina [nTPM]":"19.6","Tissue RNA - white matter [nTPM]":"58.7","Cell RNA - A-431 [nTPM]":"70.4","Cell RNA - A549 [nTPM]":"22.2","Cell RNA - AF22 [nTPM]":"70.9","Cell RNA - AN3-CA [nTPM]":"30.6","Cell RNA - ASC diff [nTPM]":"94.1","Cell RNA - ASC TERT1 [nTPM]":"90.6","Cell RNA - BEWO [nTPM]":"20.3","Cell RNA - BJ [nTPM]":"26.8","Cell RNA - BJ hTERT+ [nTPM]":"186.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"32.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"62.7","Cell RNA - CACO-2 [nTPM]":"73.9","Cell RNA - CAPAN-2 [nTPM]":"54.4","Cell RNA - Daudi [nTPM]":"15.4","Cell RNA - EFO-21 [nTPM]":"22.3","Cell RNA - fHDF\/TERT166 [nTPM]":"51.7","Cell RNA - GAMG [nTPM]":"234.6","Cell RNA - HaCaT [nTPM]":"32.7","Cell RNA - HAP1 [nTPM]":"63.2","Cell RNA - HBEC3-KT [nTPM]":"110.9","Cell RNA - HBF TERT88 [nTPM]":"12.9","Cell RNA - HDLM-2 [nTPM]":"14.9","Cell RNA - HEK 293 [nTPM]":"34.5","Cell RNA - HEL [nTPM]":"37.7","Cell RNA - HeLa [nTPM]":"38.6","Cell RNA - Hep G2 [nTPM]":"48.3","Cell RNA - HHSteC [nTPM]":"85.5","Cell RNA - HL-60 [nTPM]":"13.7","Cell RNA - HMC-1 [nTPM]":"25.1","Cell RNA - HSkMC [nTPM]":"89.0","Cell RNA - hTCEpi [nTPM]":"41.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"59.7","Cell RNA - hTERT-HME1 [nTPM]":"25.6","Cell RNA - hTERT-RPE1 [nTPM]":"22.2","Cell RNA - HUVEC TERT2 [nTPM]":"26.9","Cell RNA - JURKAT [nTPM]":"72.1","Cell RNA - K-562 [nTPM]":"37.4","Cell RNA - Karpas-707 [nTPM]":"87.3","Cell RNA - LHCN-M2 [nTPM]":"27.8","Cell RNA - MCF7 [nTPM]":"23.8","Cell RNA - MOLT-4 [nTPM]":"29.9","Cell RNA - NB-4 [nTPM]":"19.7","Cell RNA - NTERA-2 [nTPM]":"115.4","Cell RNA - OE19 [nTPM]":"11.3","Cell RNA - PC-3 [nTPM]":"20.1","Cell RNA - REH [nTPM]":"34.9","Cell RNA - RH-30 [nTPM]":"21.9","Cell RNA - RPMI-8226 [nTPM]":"92.2","Cell RNA - RPTEC TERT1 [nTPM]":"82.8","Cell RNA - RT4 [nTPM]":"38.1","Cell RNA - SCLC-21H [nTPM]":"41.4","Cell RNA - SH-SY5Y [nTPM]":"36.7","Cell RNA - SiHa [nTPM]":"31.4","Cell RNA - SK-BR-3 [nTPM]":"24.0","Cell RNA - SK-MEL-30 [nTPM]":"27.5","Cell RNA - SuSa [nTPM]":"30.6","Cell RNA - T-47d [nTPM]":"38.0","Cell RNA - THP-1 [nTPM]":"33.7","Cell RNA - TIME [nTPM]":"40.8","Cell RNA - U-138 MG [nTPM]":"37.9","Cell RNA - U-2 OS [nTPM]":"30.2","Cell RNA - U-2197 [nTPM]":"33.8","Cell RNA - U-251 MG [nTPM]":"21.1","Cell RNA - U-266\/70 [nTPM]":"31.8","Cell RNA - U-266\/84 [nTPM]":"29.5","Cell RNA - U-698 [nTPM]":"30.6","Cell RNA - U-87 MG [nTPM]":"39.7","Cell RNA - U-937 [nTPM]":"59.4","Cell RNA - WM-115 [nTPM]":"16.6","Blood RNA - basophil [nTPM]":"4.6","Blood RNA - classical monocyte [nTPM]":"2.1","Blood RNA - eosinophil [nTPM]":"2.2","Blood RNA - gdT-cell [nTPM]":"4.0","Blood RNA - intermediate monocyte [nTPM]":"1.8","Blood RNA - MAIT T-cell [nTPM]":"2.8","Blood RNA - memory B-cell [nTPM]":"3.1","Blood RNA - memory CD4 T-cell [nTPM]":"2.9","Blood RNA - memory CD8 T-cell [nTPM]":"4.9","Blood RNA - myeloid DC [nTPM]":"2.4","Blood RNA - naive B-cell [nTPM]":"1.5","Blood RNA - naive CD4 T-cell [nTPM]":"2.4","Blood RNA - naive CD8 T-cell [nTPM]":"3.6","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.7","Blood RNA - non-classical monocyte [nTPM]":"1.5","Blood RNA - plasmacytoid DC [nTPM]":"5.0","Blood RNA - T-reg [nTPM]":"1.4","Blood RNA - total PBMC [nTPM]":"3.6","Brain RNA - amygdala [nTPM]":"20.0","Brain RNA - basal ganglia [nTPM]":"30.8","Brain RNA - cerebellum [nTPM]":"38.9","Brain RNA - cerebral cortex [nTPM]":"33.5","Brain RNA - hippocampal formation [nTPM]":"15.7","Brain RNA - hypothalamus [nTPM]":"26.2","Brain RNA - medulla oblongata [nTPM]":"62.3","Brain RNA - midbrain [nTPM]":"40.7","Brain RNA - pons [nTPM]":"65.7","Brain RNA - spinal cord [nTPM]":"28.4","Brain RNA - thalamus [nTPM]":"40.4","Brain RNA - white matter [nTPM]":"58.7","Single Cell Type RNA - Adipocytes [nTPM]":"13.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"36.8","Single Cell Type RNA - Astrocytes [nTPM]":"66.6","Single Cell Type RNA - B-cells [nTPM]":"7.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"37.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"16.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"18.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.7","Single Cell Type RNA - dendritic cells [nTPM]":"11.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"10.5","Single Cell Type RNA - Early spermatids [nTPM]":"6.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.4","Single Cell Type RNA - Endothelial cells [nTPM]":"10.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.7","Single Cell Type RNA - Erythroid cells [nTPM]":"16.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"21.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.7","Single Cell Type RNA - Fibroblasts [nTPM]":"19.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.6","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"20.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.4","Single Cell Type RNA - Hepatocytes [nTPM]":"132.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.7","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.6","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"7.5","Single Cell Type RNA - Langerhans cells [nTPM]":"13.7","Single Cell Type RNA - Late spermatids [nTPM]":"6.6","Single Cell Type RNA - Leydig cells [nTPM]":"21.1","Single Cell Type RNA - Macrophages [nTPM]":"4.9","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"12.0","Single Cell Type RNA - Muller glia cells [nTPM]":"7.5","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"22.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"158.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.0","Single Cell Type RNA - Paneth cells [nTPM]":"2.7","Single Cell Type RNA - Peritubular cells [nTPM]":"13.5","Single Cell Type RNA - Plasma cells [nTPM]":"6.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.5","Single Cell Type RNA - Spermatocytes [nTPM]":"20.3","Single Cell Type RNA - Spermatogonia [nTPM]":"18.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"54.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.3","Single Cell Type RNA - T-cells [nTPM]":"7.9","Single Cell Type RNA - Theca cells [nTPM]":"18.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.9","Single Cell Type RNA - Urothelial cells [nTPM]":"4.6"},{"Gene":"LTC4S","Gene synonym":["MGC33147"],"Ensembl":"ENSG00000213316","Gene description":"Leukotriene C4 synthase","Uniprot":["Q16873"],"Chromosome":"5","Position":"179793980-179796647","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Leukotriene biosynthesis","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Lyase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"granulocytes":"327.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"20.2","eosinophil":"63.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"63.1"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"HMC-1":"102.0"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044688"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Endoplasmic reticulum","Cytosol"],"Antibody RRID":{"HPA044688":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-3"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-1"},"Tissue RNA - adipose tissue [nTPM]":"8.9","Tissue RNA - adrenal gland [nTPM]":"6.9","Tissue RNA - amygdala [nTPM]":"1.1","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"0.8","Tissue RNA - bone marrow [nTPM]":"2.3","Tissue RNA - breast [nTPM]":"5.5","Tissue RNA - cerebellum [nTPM]":"1.5","Tissue RNA - cerebral cortex [nTPM]":"1.3","Tissue RNA - cervix [nTPM]":"4.2","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"3.3","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"5.7","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"3.1","Tissue RNA - fallopian tube [nTPM]":"11.8","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"12.4","Tissue RNA - hippocampal formation [nTPM]":"1.0","Tissue RNA - hypothalamus [nTPM]":"1.4","Tissue RNA - kidney [nTPM]":"7.1","Tissue RNA - liver [nTPM]":"1.9","Tissue RNA - lung [nTPM]":"7.7","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"2.1","Tissue RNA - midbrain [nTPM]":"1.5","Tissue RNA - ovary [nTPM]":"5.7","Tissue RNA - pancreas [nTPM]":"2.0","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"3.5","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"1.4","Tissue RNA - prostate [nTPM]":"4.8","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"4.3","Tissue RNA - seminal vesicle [nTPM]":"0.8","Tissue RNA - skeletal muscle [nTPM]":"1.0","Tissue RNA - skin 1 [nTPM]":"3.1","Tissue RNA - small intestine [nTPM]":"3.2","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"2.9","Tissue RNA - spleen [nTPM]":"6.1","Tissue RNA - stomach 1 [nTPM]":"3.0","Tissue RNA - testis [nTPM]":"1.5","Tissue RNA - thalamus [nTPM]":"2.6","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"5.9","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"4.8","Tissue RNA - vagina [nTPM]":"4.0","Tissue RNA - white matter [nTPM]":"4.7","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.9","Cell RNA - HEK 293 [nTPM]":"0.9","Cell RNA - HEL [nTPM]":"8.9","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.4","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"0.6","Cell RNA - HMC-1 [nTPM]":"102.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"1.8","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"6.5","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"3.2","Cell RNA - TIME [nTPM]":"0.5","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"1.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"20.2","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"63.1","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"3.0","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"2.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.5","Blood RNA - myeloid DC [nTPM]":"8.6","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"1.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"4.7","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"1.1","Brain RNA - basal ganglia [nTPM]":"0.8","Brain RNA - cerebellum [nTPM]":"1.5","Brain RNA - cerebral cortex [nTPM]":"1.3","Brain RNA - hippocampal formation [nTPM]":"1.0","Brain RNA - hypothalamus [nTPM]":"1.4","Brain RNA - medulla oblongata [nTPM]":"2.1","Brain RNA - midbrain [nTPM]":"1.5","Brain RNA - pons [nTPM]":"1.4","Brain RNA - spinal cord [nTPM]":"2.9","Brain RNA - thalamus [nTPM]":"2.6","Brain RNA - white matter [nTPM]":"4.7","Single Cell Type RNA - Adipocytes [nTPM]":"32.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.2","Single Cell Type RNA - Astrocytes [nTPM]":"2.9","Single Cell Type RNA - B-cells [nTPM]":"2.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"38.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"6.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.4","Single Cell Type RNA - dendritic cells [nTPM]":"5.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.5","Single Cell Type RNA - Endothelial cells [nTPM]":"49.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.9","Single Cell Type RNA - Fibroblasts [nTPM]":"8.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.6","Single Cell Type RNA - granulocytes [nTPM]":"327.4","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"72.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"41.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"20.8","Single Cell Type RNA - Langerhans cells [nTPM]":"46.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"16.4","Single Cell Type RNA - Macrophages [nTPM]":"53.9","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"28.1","Single Cell Type RNA - monocytes [nTPM]":"2.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.5","Single Cell Type RNA - Peritubular cells [nTPM]":"47.4","Single Cell Type RNA - Plasma cells [nTPM]":"10.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"54.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.0","Single Cell Type RNA - T-cells [nTPM]":"10.0","Single Cell Type RNA - Theca cells [nTPM]":"1.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.1","Single Cell Type RNA - Urothelial cells [nTPM]":"10.0"},{"Gene":"LTK","Gene synonym":["TYK1"],"Ensembl":"ENSG00000062524","Gene description":"Leukocyte receptor tyrosine kinase","Uniprot":["P29376"],"Chromosome":"15","Position":"41503637-41513887","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Systemic lupus erythematosus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"13.2","lung":"15.1","salivary gland":"11.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"25.3","Gastric mucus-secreting cells":"18.8","Hepatic stellate cells":"11.4","Intestinal goblet cells":"7.9","Proximal enterocytes":"15.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"MAIT T-cell":"5.7","plasmacytoid DC":"5.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"dendritic cells":"5.0","T-cells":"5.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"5.0","NB-4":"9.7","RH-30":"4.6","THP-1":"14.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059545"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA059545":"AB_2684057"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.47e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.36e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.8","Tissue RNA - adrenal gland [nTPM]":"0.6","Tissue RNA - amygdala [nTPM]":"1.0","Tissue RNA - appendix [nTPM]":"1.4","Tissue RNA - basal ganglia [nTPM]":"1.6","Tissue RNA - bone marrow [nTPM]":"4.6","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"1.2","Tissue RNA - cerebral cortex [nTPM]":"1.8","Tissue RNA - cervix [nTPM]":"0.9","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"5.2","Tissue RNA - duodenum [nTPM]":"12.5","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"2.4","Tissue RNA - heart muscle [nTPM]":"1.7","Tissue RNA - hippocampal formation [nTPM]":"1.3","Tissue RNA - hypothalamus [nTPM]":"0.7","Tissue RNA - kidney [nTPM]":"4.0","Tissue RNA - liver [nTPM]":"2.9","Tissue RNA - lung [nTPM]":"15.1","Tissue RNA - lymph node [nTPM]":"1.2","Tissue RNA - medulla oblongata [nTPM]":"0.6","Tissue RNA - midbrain [nTPM]":"0.6","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.6","Tissue RNA - pituitary gland [nTPM]":"0.7","Tissue RNA - placenta [nTPM]":"10.4","Tissue RNA - pons [nTPM]":"0.7","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"5.7","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"11.8","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"1.8","Tissue RNA - skin 1 [nTPM]":"1.4","Tissue RNA - small intestine [nTPM]":"13.2","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"5.5","Tissue RNA - stomach 1 [nTPM]":"9.9","Tissue RNA - testis [nTPM]":"2.5","Tissue RNA - thalamus [nTPM]":"0.8","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"2.1","Tissue RNA - urinary bladder [nTPM]":"0.7","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"0.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.2","Cell RNA - CACO-2 [nTPM]":"2.2","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.6","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"2.6","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"1.3","Cell RNA - HEL [nTPM]":"5.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"2.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"1.9","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"1.8","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"9.7","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"1.8","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"4.6","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"2.9","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"2.6","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"14.7","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.5","Cell RNA - WM-115 [nTPM]":"0.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"5.7","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"1.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"5.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"1.0","Brain RNA - basal ganglia [nTPM]":"1.6","Brain RNA - cerebellum [nTPM]":"1.2","Brain RNA - cerebral cortex [nTPM]":"1.8","Brain RNA - hippocampal formation [nTPM]":"1.3","Brain RNA - hypothalamus [nTPM]":"0.7","Brain RNA - medulla oblongata [nTPM]":"0.6","Brain RNA - midbrain [nTPM]":"0.6","Brain RNA - pons [nTPM]":"0.7","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"0.8","Brain RNA - white matter [nTPM]":"0.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"1.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"0.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"5.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"25.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"3.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.5","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"0.6","Single Cell Type RNA - Late spermatids [nTPM]":"2.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.7","Single Cell Type RNA - Paneth cells [nTPM]":"5.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"2.2","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"4.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.8","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"LYN","Gene synonym":["JTK8"],"Ensembl":"ENSG00000254087","Gene description":"LYN proto-oncogene, Src family tyrosine kinase","Uniprot":["P07948"],"Chromosome":"8","Position":"55879835-56014169","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"73.8","lymphoid tissue":"85.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"237.5","Kupffer cells":"183.7","Macrophages":"226.0","monocytes":"182.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"64.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"198.4","HMC-1":"193.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001231","CAB004492"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"770000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Golgi apparatus","Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB004492":"AB_627897","HPA001231":"AB_1079286"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.43e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Tissue RNA - adipose tissue [nTPM]":"17.2","Tissue RNA - adrenal gland [nTPM]":"7.3","Tissue RNA - amygdala [nTPM]":"3.9","Tissue RNA - appendix [nTPM]":"79.2","Tissue RNA - basal ganglia [nTPM]":"4.0","Tissue RNA - bone marrow [nTPM]":"73.8","Tissue RNA - breast [nTPM]":"9.2","Tissue RNA - cerebellum [nTPM]":"7.4","Tissue RNA - cerebral cortex [nTPM]":"8.7","Tissue RNA - cervix [nTPM]":"11.0","Tissue RNA - choroid plexus [nTPM]":"7.8","Tissue RNA - colon [nTPM]":"14.2","Tissue RNA - duodenum [nTPM]":"36.3","Tissue RNA - endometrium 1 [nTPM]":"6.2","Tissue RNA - epididymis [nTPM]":"4.8","Tissue RNA - esophagus [nTPM]":"8.6","Tissue RNA - fallopian tube [nTPM]":"10.0","Tissue RNA - gallbladder [nTPM]":"23.5","Tissue RNA - heart muscle [nTPM]":"5.4","Tissue RNA - hippocampal formation [nTPM]":"4.4","Tissue RNA - hypothalamus [nTPM]":"5.5","Tissue RNA - kidney [nTPM]":"5.9","Tissue RNA - liver [nTPM]":"14.9","Tissue RNA - lung [nTPM]":"28.2","Tissue RNA - lymph node [nTPM]":"49.2","Tissue RNA - medulla oblongata [nTPM]":"9.4","Tissue RNA - midbrain [nTPM]":"7.2","Tissue RNA - ovary [nTPM]":"3.6","Tissue RNA - pancreas [nTPM]":"9.5","Tissue RNA - parathyroid gland [nTPM]":"6.3","Tissue RNA - pituitary gland [nTPM]":"4.8","Tissue RNA - placenta [nTPM]":"23.5","Tissue RNA - pons [nTPM]":"8.3","Tissue RNA - prostate [nTPM]":"5.6","Tissue RNA - rectum [nTPM]":"13.3","Tissue RNA - retina [nTPM]":"8.9","Tissue RNA - salivary gland [nTPM]":"17.0","Tissue RNA - seminal vesicle [nTPM]":"9.7","Tissue RNA - skeletal muscle [nTPM]":"1.6","Tissue RNA - skin 1 [nTPM]":"3.7","Tissue RNA - small intestine [nTPM]":"31.6","Tissue RNA - smooth muscle [nTPM]":"14.2","Tissue RNA - spinal cord [nTPM]":"7.2","Tissue RNA - spleen [nTPM]":"85.4","Tissue RNA - stomach 1 [nTPM]":"13.3","Tissue RNA - testis [nTPM]":"3.1","Tissue RNA - thalamus [nTPM]":"9.0","Tissue RNA - thymus [nTPM]":"10.4","Tissue RNA - thyroid gland [nTPM]":"10.6","Tissue RNA - tongue [nTPM]":"4.4","Tissue RNA - tonsil [nTPM]":"53.1","Tissue RNA - urinary bladder [nTPM]":"29.7","Tissue RNA - vagina [nTPM]":"5.7","Tissue RNA - white matter [nTPM]":"11.2","Cell RNA - A-431 [nTPM]":"47.2","Cell RNA - A549 [nTPM]":"24.6","Cell RNA - AF22 [nTPM]":"6.9","Cell RNA - AN3-CA [nTPM]":"0.7","Cell RNA - ASC diff [nTPM]":"0.5","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"43.6","Cell RNA - BJ [nTPM]":"34.6","Cell RNA - BJ hTERT+ [nTPM]":"54.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.7","Cell RNA - CACO-2 [nTPM]":"18.0","Cell RNA - CAPAN-2 [nTPM]":"15.5","Cell RNA - Daudi [nTPM]":"41.2","Cell RNA - EFO-21 [nTPM]":"15.0","Cell RNA - fHDF\/TERT166 [nTPM]":"12.1","Cell RNA - GAMG [nTPM]":"15.3","Cell RNA - HaCaT [nTPM]":"19.3","Cell RNA - HAP1 [nTPM]":"22.2","Cell RNA - HBEC3-KT [nTPM]":"23.8","Cell RNA - HBF TERT88 [nTPM]":"14.6","Cell RNA - HDLM-2 [nTPM]":"70.0","Cell RNA - HEK 293 [nTPM]":"19.8","Cell RNA - HEL [nTPM]":"198.4","Cell RNA - HeLa [nTPM]":"6.9","Cell RNA - Hep G2 [nTPM]":"5.5","Cell RNA - HHSteC [nTPM]":"4.0","Cell RNA - HL-60 [nTPM]":"20.6","Cell RNA - HMC-1 [nTPM]":"193.4","Cell RNA - HSkMC [nTPM]":"0.8","Cell RNA - hTCEpi [nTPM]":"7.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.6","Cell RNA - hTERT-HME1 [nTPM]":"13.6","Cell RNA - hTERT-RPE1 [nTPM]":"13.1","Cell RNA - HUVEC TERT2 [nTPM]":"27.2","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"98.3","Cell RNA - Karpas-707 [nTPM]":"90.2","Cell RNA - LHCN-M2 [nTPM]":"3.0","Cell RNA - MCF7 [nTPM]":"3.3","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"21.5","Cell RNA - NTERA-2 [nTPM]":"38.6","Cell RNA - OE19 [nTPM]":"72.9","Cell RNA - PC-3 [nTPM]":"2.1","Cell RNA - REH [nTPM]":"3.3","Cell RNA - RH-30 [nTPM]":"9.6","Cell RNA - RPMI-8226 [nTPM]":"5.0","Cell RNA - RPTEC TERT1 [nTPM]":"9.8","Cell RNA - RT4 [nTPM]":"24.9","Cell RNA - SCLC-21H [nTPM]":"4.5","Cell RNA - SH-SY5Y [nTPM]":"74.8","Cell RNA - SiHa [nTPM]":"17.3","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"7.5","Cell RNA - SuSa [nTPM]":"44.9","Cell RNA - T-47d [nTPM]":"3.4","Cell RNA - THP-1 [nTPM]":"41.4","Cell RNA - TIME [nTPM]":"33.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"10.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"15.0","Cell RNA - U-266\/70 [nTPM]":"26.4","Cell RNA - U-266\/84 [nTPM]":"13.2","Cell RNA - U-698 [nTPM]":"102.4","Cell RNA - U-87 MG [nTPM]":"1.5","Cell RNA - U-937 [nTPM]":"38.8","Cell RNA - WM-115 [nTPM]":"1.7","Blood RNA - basophil [nTPM]":"4.5","Blood RNA - classical monocyte [nTPM]":"12.2","Blood RNA - eosinophil [nTPM]":"22.7","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"28.3","Blood RNA - MAIT T-cell [nTPM]":"1.3","Blood RNA - memory B-cell [nTPM]":"15.9","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"10.3","Blood RNA - naive B-cell [nTPM]":"16.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"64.4","Blood RNA - NK-cell [nTPM]":"4.3","Blood RNA - non-classical monocyte [nTPM]":"49.1","Blood RNA - plasmacytoid DC [nTPM]":"16.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"5.0","Brain RNA - amygdala [nTPM]":"3.9","Brain RNA - basal ganglia [nTPM]":"4.0","Brain RNA - cerebellum [nTPM]":"7.4","Brain RNA - cerebral cortex [nTPM]":"8.7","Brain RNA - hippocampal formation [nTPM]":"4.4","Brain RNA - hypothalamus [nTPM]":"5.5","Brain RNA - medulla oblongata [nTPM]":"9.4","Brain RNA - midbrain [nTPM]":"7.2","Brain RNA - pons [nTPM]":"8.3","Brain RNA - spinal cord [nTPM]":"7.2","Brain RNA - thalamus [nTPM]":"9.0","Brain RNA - white matter [nTPM]":"11.2","Single Cell Type RNA - Adipocytes [nTPM]":"21.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"37.5","Single Cell Type RNA - Astrocytes [nTPM]":"27.7","Single Cell Type RNA - B-cells [nTPM]":"237.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"32.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"6.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"44.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.9","Single Cell Type RNA - dendritic cells [nTPM]":"130.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"21.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.2","Single Cell Type RNA - Endothelial cells [nTPM]":"28.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"40.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"53.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"65.2","Single Cell Type RNA - Fibroblasts [nTPM]":"13.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.9","Single Cell Type RNA - granulocytes [nTPM]":"72.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.9","Single Cell Type RNA - Hepatocytes [nTPM]":"13.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"126.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.1","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"183.7","Single Cell Type RNA - Langerhans cells [nTPM]":"96.1","Single Cell Type RNA - Late spermatids [nTPM]":"2.4","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"226.0","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"92.8","Single Cell Type RNA - monocytes [nTPM]":"182.6","Single Cell Type RNA - Muller glia cells [nTPM]":"54.3","Single Cell Type RNA - NK-cells [nTPM]":"94.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"40.7","Single Cell Type RNA - Paneth cells [nTPM]":"13.3","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"58.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"62.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"26.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"40.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.6","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.4","Single Cell Type RNA - Spermatocytes [nTPM]":"1.2","Single Cell Type RNA - Spermatogonia [nTPM]":"2.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"38.7","Single Cell Type RNA - T-cells [nTPM]":"25.0","Single Cell Type RNA - Theca cells [nTPM]":"62.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.1","Single Cell Type RNA - Urothelial cells [nTPM]":"82.4"},{"Gene":"LYZ","Gene synonym":[],"Ensembl":"ENSG00000090382","Gene description":"Lysozyme","Uniprot":["P61626"],"Chromosome":"12","Position":"69348381-69354234","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Antimicrobial","Bacteriolytic enzyme","Glycosidase","Hydrolase"],"Disease involvement":["Amyloidosis","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"10588.1","salivary gland":"21115.5","stomach 1":"8941.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"3106.1","Kupffer cells":"2841.2","Langerhans cells":"4859.1","Macrophages":"4870.7","monocytes":"7063.0","Pancreatic endocrine cells":"3152.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"stomach cancer":"976.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"25266.2","myeloid DC":"14438.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"20","RNA blood lineage specific nTPM":{"dendritic cells":"14438.7","monocytes":"25266.2"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"13","RNA cell line specific nTPM":{"OE19":"12130.8"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000055","HPA048284","HPA066182"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Actin filaments"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":1500000000,"Blood concentration - Conc. blood MS [pg\/L]":"1500000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":["Golgi apparatus","Actin filaments"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB000055":"AB_2341230","HPA048284":"AB_2680339","HPA066182":"AB_2732741"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.45e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Tissue RNA - adipose tissue [nTPM]":"95.8","Tissue RNA - adrenal gland [nTPM]":"27.8","Tissue RNA - amygdala [nTPM]":"3.5","Tissue RNA - appendix [nTPM]":"802.1","Tissue RNA - basal ganglia [nTPM]":"4.0","Tissue RNA - bone marrow [nTPM]":"10588.1","Tissue RNA - breast [nTPM]":"128.2","Tissue RNA - cerebellum [nTPM]":"3.7","Tissue RNA - cerebral cortex [nTPM]":"18.5","Tissue RNA - cervix [nTPM]":"156.2","Tissue RNA - choroid plexus [nTPM]":"11.4","Tissue RNA - colon [nTPM]":"309.0","Tissue RNA - duodenum [nTPM]":"3605.0","Tissue RNA - endometrium 1 [nTPM]":"65.7","Tissue RNA - epididymis [nTPM]":"4.2","Tissue RNA - esophagus [nTPM]":"106.3","Tissue RNA - fallopian tube [nTPM]":"33.9","Tissue RNA - gallbladder [nTPM]":"1054.6","Tissue RNA - heart muscle [nTPM]":"34.8","Tissue RNA - hippocampal formation [nTPM]":"2.6","Tissue RNA - hypothalamus [nTPM]":"4.3","Tissue RNA - kidney [nTPM]":"32.4","Tissue RNA - liver [nTPM]":"138.0","Tissue RNA - lung [nTPM]":"1355.2","Tissue RNA - lymph node [nTPM]":"739.7","Tissue RNA - medulla oblongata [nTPM]":"8.0","Tissue RNA - midbrain [nTPM]":"7.3","Tissue RNA - ovary [nTPM]":"20.4","Tissue RNA - pancreas [nTPM]":"63.1","Tissue RNA - parathyroid gland [nTPM]":"13.8","Tissue RNA - pituitary gland [nTPM]":"7.2","Tissue RNA - placenta [nTPM]":"91.3","Tissue RNA - pons [nTPM]":"12.2","Tissue RNA - prostate [nTPM]":"40.2","Tissue RNA - rectum [nTPM]":"273.8","Tissue RNA - retina [nTPM]":"4.4","Tissue RNA - salivary gland [nTPM]":"21115.5","Tissue RNA - seminal vesicle [nTPM]":"21.8","Tissue RNA - skeletal muscle [nTPM]":"34.0","Tissue RNA - skin 1 [nTPM]":"58.7","Tissue RNA - small intestine [nTPM]":"1322.2","Tissue RNA - smooth muscle [nTPM]":"123.9","Tissue RNA - spinal cord [nTPM]":"5.4","Tissue RNA - spleen [nTPM]":"621.0","Tissue RNA - stomach 1 [nTPM]":"8941.1","Tissue RNA - testis [nTPM]":"21.8","Tissue RNA - thalamus [nTPM]":"10.9","Tissue RNA - thymus [nTPM]":"321.8","Tissue RNA - thyroid gland [nTPM]":"27.8","Tissue RNA - tongue [nTPM]":"36.4","Tissue RNA - tonsil [nTPM]":"652.8","Tissue RNA - urinary bladder [nTPM]":"428.5","Tissue RNA - vagina [nTPM]":"16.2","Tissue RNA - white matter [nTPM]":"11.7","Cell RNA - A-431 [nTPM]":"0.6","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"4.8","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"9.5","Cell RNA - CAPAN-2 [nTPM]":"6.5","Cell RNA - Daudi [nTPM]":"4.2","Cell RNA - EFO-21 [nTPM]":"1.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"3.6","Cell RNA - HaCaT [nTPM]":"1.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"1.2","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"62.4","Cell RNA - HeLa [nTPM]":"1.0","Cell RNA - Hep G2 [nTPM]":"960.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"110.6","Cell RNA - HMC-1 [nTPM]":"50.5","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"7.7","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"2.6","Cell RNA - NB-4 [nTPM]":"109.5","Cell RNA - NTERA-2 [nTPM]":"2.3","Cell RNA - OE19 [nTPM]":"12130.8","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"1.6","Cell RNA - RH-30 [nTPM]":"1.4","Cell RNA - RPMI-8226 [nTPM]":"16.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.3","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.8","Cell RNA - SH-SY5Y [nTPM]":"3.6","Cell RNA - SiHa [nTPM]":"0.5","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.5","Cell RNA - SuSa [nTPM]":"0.7","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"489.0","Cell RNA - TIME [nTPM]":"0.6","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"2.6","Cell RNA - U-2197 [nTPM]":"2.3","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"2.6","Cell RNA - U-266\/84 [nTPM]":"1.1","Cell RNA - U-698 [nTPM]":"1.2","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"518.5","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"443.4","Blood RNA - classical monocyte [nTPM]":"25266.2","Blood RNA - eosinophil [nTPM]":"298.2","Blood RNA - gdT-cell [nTPM]":"32.6","Blood RNA - intermediate monocyte [nTPM]":"4798.4","Blood RNA - MAIT T-cell [nTPM]":"52.3","Blood RNA - memory B-cell [nTPM]":"100.5","Blood RNA - memory CD4 T-cell [nTPM]":"20.1","Blood RNA - memory CD8 T-cell [nTPM]":"22.7","Blood RNA - myeloid DC [nTPM]":"14438.7","Blood RNA - naive B-cell [nTPM]":"20.8","Blood RNA - naive CD4 T-cell [nTPM]":"20.0","Blood RNA - naive CD8 T-cell [nTPM]":"17.8","Blood RNA - neutrophil [nTPM]":"1007.7","Blood RNA - NK-cell [nTPM]":"108.1","Blood RNA - non-classical monocyte [nTPM]":"880.1","Blood RNA - plasmacytoid DC [nTPM]":"301.2","Blood RNA - T-reg [nTPM]":"31.1","Blood RNA - total PBMC [nTPM]":"25392.1","Brain RNA - amygdala [nTPM]":"3.5","Brain RNA - basal ganglia [nTPM]":"4.0","Brain RNA - cerebellum [nTPM]":"3.7","Brain RNA - cerebral cortex [nTPM]":"18.5","Brain RNA - hippocampal formation [nTPM]":"2.6","Brain RNA - hypothalamus [nTPM]":"4.3","Brain RNA - medulla oblongata [nTPM]":"8.0","Brain RNA - midbrain [nTPM]":"7.3","Brain RNA - pons [nTPM]":"12.2","Brain RNA - spinal cord [nTPM]":"5.4","Brain RNA - thalamus [nTPM]":"10.9","Brain RNA - white matter [nTPM]":"11.7","Single Cell Type RNA - Adipocytes [nTPM]":"24.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"86.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"285.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"80.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"57.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"1205.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"32.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"734.9","Single Cell Type RNA - Club cells [nTPM]":"51.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.6","Single Cell Type RNA - dendritic cells [nTPM]":"39.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"32.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"55.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.9","Single Cell Type RNA - Endothelial cells [nTPM]":"25.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.5","Single Cell Type RNA - Erythroid cells [nTPM]":"264.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"547.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.4","Single Cell Type RNA - Fibroblasts [nTPM]":"26.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3106.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.9","Single Cell Type RNA - granulocytes [nTPM]":"123.6","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"29.6","Single Cell Type RNA - Hepatocytes [nTPM]":"25.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"887.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"112.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2841.2","Single Cell Type RNA - Langerhans cells [nTPM]":"4859.1","Single Cell Type RNA - Late spermatids [nTPM]":"17.4","Single Cell Type RNA - Leydig cells [nTPM]":"4.1","Single Cell Type RNA - Macrophages [nTPM]":"4870.7","Single Cell Type RNA - Melanocytes [nTPM]":"53.4","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"7063.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"176.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3152.5","Single Cell Type RNA - Paneth cells [nTPM]":"600.5","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"9.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"41.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"3.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"38.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.5","Single Cell Type RNA - T-cells [nTPM]":"50.6","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"111.4","Single Cell Type RNA - Urothelial cells [nTPM]":"38.3"},{"Gene":"MACF1","Gene synonym":["ABP620","ACF7","FLJ45612","FLJ46776","KIAA0465","KIAA1251","MACF"],"Ensembl":"ENSG00000127603","Gene description":"Microtubule actin crosslinking factor 1","Uniprot":["Q9UPN3"],"Chromosome":"1","Position":"39081316-39487177","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Actin-binding"],"Disease involvement":["Disease variant","Lissencephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"1079.0","Cone photoreceptor cells":"779.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013713","HPA068064","HPA068103"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cell Junctions","Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"25000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Plasma membrane","Cell Junctions","Actin filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA013713":"AB_10600821","HPA068064":"AB_2685946","HPA068103":"AB_2685953"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.77e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"},"Tissue RNA - adipose tissue [nTPM]":"69.1","Tissue RNA - adrenal gland [nTPM]":"62.5","Tissue RNA - amygdala [nTPM]":"172.0","Tissue RNA - appendix [nTPM]":"27.7","Tissue RNA - basal ganglia [nTPM]":"197.5","Tissue RNA - bone marrow [nTPM]":"36.2","Tissue RNA - breast [nTPM]":"54.6","Tissue RNA - cerebellum [nTPM]":"174.6","Tissue RNA - cerebral cortex [nTPM]":"181.6","Tissue RNA - cervix [nTPM]":"65.9","Tissue RNA - choroid plexus [nTPM]":"119.1","Tissue RNA - colon [nTPM]":"148.6","Tissue RNA - duodenum [nTPM]":"18.6","Tissue RNA - endometrium 1 [nTPM]":"130.3","Tissue RNA - epididymis [nTPM]":"48.7","Tissue RNA - esophagus [nTPM]":"46.4","Tissue RNA - fallopian tube [nTPM]":"92.0","Tissue RNA - gallbladder [nTPM]":"46.4","Tissue RNA - heart muscle [nTPM]":"127.0","Tissue RNA - hippocampal formation [nTPM]":"159.7","Tissue RNA - hypothalamus [nTPM]":"166.1","Tissue RNA - kidney [nTPM]":"85.7","Tissue RNA - liver [nTPM]":"63.8","Tissue RNA - lung [nTPM]":"183.6","Tissue RNA - lymph node [nTPM]":"35.9","Tissue RNA - medulla oblongata [nTPM]":"190.2","Tissue RNA - midbrain [nTPM]":"179.0","Tissue RNA - ovary [nTPM]":"92.6","Tissue RNA - pancreas [nTPM]":"51.2","Tissue RNA - parathyroid gland [nTPM]":"96.9","Tissue RNA - pituitary gland [nTPM]":"69.3","Tissue RNA - placenta [nTPM]":"34.6","Tissue RNA - pons [nTPM]":"182.9","Tissue RNA - prostate [nTPM]":"68.2","Tissue RNA - rectum [nTPM]":"25.1","Tissue RNA - retina [nTPM]":"121.2","Tissue RNA - salivary gland [nTPM]":"57.7","Tissue RNA - seminal vesicle [nTPM]":"41.6","Tissue RNA - skeletal muscle [nTPM]":"73.0","Tissue RNA - skin 1 [nTPM]":"121.0","Tissue RNA - small intestine [nTPM]":"62.6","Tissue RNA - smooth muscle [nTPM]":"54.2","Tissue RNA - spinal cord [nTPM]":"155.6","Tissue RNA - spleen [nTPM]":"84.9","Tissue RNA - stomach 1 [nTPM]":"71.3","Tissue RNA - testis [nTPM]":"50.2","Tissue RNA - thalamus [nTPM]":"193.2","Tissue RNA - thymus [nTPM]":"39.3","Tissue RNA - thyroid gland [nTPM]":"73.3","Tissue RNA - tongue [nTPM]":"55.2","Tissue RNA - tonsil [nTPM]":"22.8","Tissue RNA - urinary bladder [nTPM]":"80.3","Tissue RNA - vagina [nTPM]":"62.7","Tissue RNA - white matter [nTPM]":"185.3","Cell RNA - A-431 [nTPM]":"48.1","Cell RNA - A549 [nTPM]":"54.9","Cell RNA - AF22 [nTPM]":"66.7","Cell RNA - AN3-CA [nTPM]":"29.3","Cell RNA - ASC diff [nTPM]":"53.8","Cell RNA - ASC TERT1 [nTPM]":"47.3","Cell RNA - BEWO [nTPM]":"29.8","Cell RNA - BJ [nTPM]":"62.2","Cell RNA - BJ hTERT+ [nTPM]":"79.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"38.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"33.7","Cell RNA - CACO-2 [nTPM]":"34.3","Cell RNA - CAPAN-2 [nTPM]":"56.5","Cell RNA - Daudi [nTPM]":"24.4","Cell RNA - EFO-21 [nTPM]":"64.6","Cell RNA - fHDF\/TERT166 [nTPM]":"84.0","Cell RNA - GAMG [nTPM]":"62.1","Cell RNA - HaCaT [nTPM]":"30.6","Cell RNA - HAP1 [nTPM]":"12.5","Cell RNA - HBEC3-KT [nTPM]":"45.7","Cell RNA - HBF TERT88 [nTPM]":"51.2","Cell RNA - HDLM-2 [nTPM]":"43.5","Cell RNA - HEK 293 [nTPM]":"33.1","Cell RNA - HEL [nTPM]":"34.0","Cell RNA - HeLa [nTPM]":"43.4","Cell RNA - Hep G2 [nTPM]":"56.5","Cell RNA - HHSteC [nTPM]":"66.0","Cell RNA - HL-60 [nTPM]":"30.8","Cell RNA - HMC-1 [nTPM]":"15.9","Cell RNA - HSkMC [nTPM]":"37.0","Cell RNA - hTCEpi [nTPM]":"46.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"105.1","Cell RNA - hTERT-HME1 [nTPM]":"54.3","Cell RNA - hTERT-RPE1 [nTPM]":"83.5","Cell RNA - HUVEC TERT2 [nTPM]":"104.7","Cell RNA - JURKAT [nTPM]":"52.0","Cell RNA - K-562 [nTPM]":"63.2","Cell RNA - Karpas-707 [nTPM]":"25.7","Cell RNA - LHCN-M2 [nTPM]":"137.0","Cell RNA - MCF7 [nTPM]":"16.0","Cell RNA - MOLT-4 [nTPM]":"23.3","Cell RNA - NB-4 [nTPM]":"52.7","Cell RNA - NTERA-2 [nTPM]":"95.8","Cell RNA - OE19 [nTPM]":"20.0","Cell RNA - PC-3 [nTPM]":"31.7","Cell RNA - REH [nTPM]":"38.5","Cell RNA - RH-30 [nTPM]":"89.6","Cell RNA - RPMI-8226 [nTPM]":"4.5","Cell RNA - RPTEC TERT1 [nTPM]":"206.0","Cell RNA - RT4 [nTPM]":"50.8","Cell RNA - SCLC-21H [nTPM]":"38.2","Cell RNA - SH-SY5Y [nTPM]":"38.6","Cell RNA - SiHa [nTPM]":"24.9","Cell RNA - SK-BR-3 [nTPM]":"17.2","Cell RNA - SK-MEL-30 [nTPM]":"62.5","Cell RNA - SuSa [nTPM]":"76.3","Cell RNA - T-47d [nTPM]":"7.5","Cell RNA - THP-1 [nTPM]":"37.9","Cell RNA - TIME [nTPM]":"115.1","Cell RNA - U-138 MG [nTPM]":"61.6","Cell RNA - U-2 OS [nTPM]":"48.5","Cell RNA - U-2197 [nTPM]":"28.8","Cell RNA - U-251 MG [nTPM]":"101.9","Cell RNA - U-266\/70 [nTPM]":"19.4","Cell RNA - U-266\/84 [nTPM]":"19.7","Cell RNA - U-698 [nTPM]":"28.8","Cell RNA - U-87 MG [nTPM]":"101.0","Cell RNA - U-937 [nTPM]":"32.6","Cell RNA - WM-115 [nTPM]":"55.2","Blood RNA - basophil [nTPM]":"7.5","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"3.8","Blood RNA - gdT-cell [nTPM]":"12.2","Blood RNA - intermediate monocyte [nTPM]":"2.7","Blood RNA - MAIT T-cell [nTPM]":"5.9","Blood RNA - memory B-cell [nTPM]":"2.2","Blood RNA - memory CD4 T-cell [nTPM]":"5.8","Blood RNA - memory CD8 T-cell [nTPM]":"7.8","Blood RNA - myeloid DC [nTPM]":"1.8","Blood RNA - naive B-cell [nTPM]":"3.8","Blood RNA - naive CD4 T-cell [nTPM]":"4.7","Blood RNA - naive CD8 T-cell [nTPM]":"6.1","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"6.5","Blood RNA - non-classical monocyte [nTPM]":"2.9","Blood RNA - plasmacytoid DC [nTPM]":"2.5","Blood RNA - T-reg [nTPM]":"3.0","Blood RNA - total PBMC [nTPM]":"2.0","Brain RNA - amygdala [nTPM]":"172.0","Brain RNA - basal ganglia [nTPM]":"197.5","Brain RNA - cerebellum [nTPM]":"174.6","Brain RNA - cerebral cortex [nTPM]":"181.6","Brain RNA - hippocampal formation [nTPM]":"159.7","Brain RNA - hypothalamus [nTPM]":"166.1","Brain RNA - medulla oblongata [nTPM]":"190.2","Brain RNA - midbrain [nTPM]":"179.0","Brain RNA - pons [nTPM]":"182.9","Brain RNA - spinal cord [nTPM]":"155.6","Brain RNA - thalamus [nTPM]":"193.2","Brain RNA - white matter [nTPM]":"185.3","Single Cell Type RNA - Adipocytes [nTPM]":"135.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"150.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"128.2","Single Cell Type RNA - Astrocytes [nTPM]":"1079.0","Single Cell Type RNA - B-cells [nTPM]":"68.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"154.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"74.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"43.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"60.3","Single Cell Type RNA - Bipolar cells [nTPM]":"387.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"52.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"50.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"246.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"61.5","Single Cell Type RNA - Club cells [nTPM]":"70.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"80.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"779.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"52.6","Single Cell Type RNA - dendritic cells [nTPM]":"120.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"35.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"113.3","Single Cell Type RNA - Early spermatids [nTPM]":"9.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"140.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"124.4","Single Cell Type RNA - Endothelial cells [nTPM]":"164.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"36.1","Single Cell Type RNA - Erythroid cells [nTPM]":"57.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"320.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"114.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"62.1","Single Cell Type RNA - Fibroblasts [nTPM]":"108.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"65.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"180.1","Single Cell Type RNA - granulocytes [nTPM]":"77.7","Single Cell Type RNA - Granulosa cells [nTPM]":"194.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"132.1","Single Cell Type RNA - Hepatocytes [nTPM]":"47.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"52.1","Single Cell Type RNA - Horizontal cells [nTPM]":"117.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"367.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"27.2","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"59.7","Single Cell Type RNA - Langerhans cells [nTPM]":"46.3","Single Cell Type RNA - Late spermatids [nTPM]":"11.8","Single Cell Type RNA - Leydig cells [nTPM]":"43.8","Single Cell Type RNA - Macrophages [nTPM]":"74.8","Single Cell Type RNA - Melanocytes [nTPM]":"71.2","Single Cell Type RNA - Microglial cells [nTPM]":"342.9","Single Cell Type RNA - monocytes [nTPM]":"59.0","Single Cell Type RNA - Muller glia cells [nTPM]":"107.8","Single Cell Type RNA - NK-cells [nTPM]":"158.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"494.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"410.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"193.5","Single Cell Type RNA - Paneth cells [nTPM]":"17.7","Single Cell Type RNA - Peritubular cells [nTPM]":"112.5","Single Cell Type RNA - Plasma cells [nTPM]":"81.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"89.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"20.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"71.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"398.5","Single Cell Type RNA - Sertoli cells [nTPM]":"105.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"95.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"136.7","Single Cell Type RNA - Spermatocytes [nTPM]":"62.6","Single Cell Type RNA - Spermatogonia [nTPM]":"33.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"43.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"191.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"69.9","Single Cell Type RNA - T-cells [nTPM]":"131.2","Single Cell Type RNA - Theca cells [nTPM]":"76.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.7","Single Cell Type RNA - Urothelial cells [nTPM]":"78.8"},{"Gene":"MACROD1","Gene synonym":["LRP16"],"Ensembl":"ENSG00000133315","Gene description":"Mono-ADP ribosylhydrolase 1","Uniprot":["Q9BQ69"],"Chromosome":"11","Position":"63998558-64166113","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"290.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"137.0","Proximal tubular cells":"333.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"73.8","RPMI-8226":"145.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041031","HPA071075"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA041031":"AB_10794435","HPA071075":"AB_2686341"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.90e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.68e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Tissue RNA - adipose tissue [nTPM]":"14.9","Tissue RNA - adrenal gland [nTPM]":"14.1","Tissue RNA - amygdala [nTPM]":"6.4","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"5.9","Tissue RNA - bone marrow [nTPM]":"2.8","Tissue RNA - breast [nTPM]":"17.3","Tissue RNA - cerebellum [nTPM]":"6.8","Tissue RNA - cerebral cortex [nTPM]":"12.7","Tissue RNA - cervix [nTPM]":"15.6","Tissue RNA - choroid plexus [nTPM]":"5.9","Tissue RNA - colon [nTPM]":"21.3","Tissue RNA - duodenum [nTPM]":"5.7","Tissue RNA - endometrium 1 [nTPM]":"13.8","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"18.6","Tissue RNA - fallopian tube [nTPM]":"15.3","Tissue RNA - gallbladder [nTPM]":"2.2","Tissue RNA - heart muscle [nTPM]":"111.6","Tissue RNA - hippocampal formation [nTPM]":"6.4","Tissue RNA - hypothalamus [nTPM]":"8.2","Tissue RNA - kidney [nTPM]":"55.1","Tissue RNA - liver [nTPM]":"50.2","Tissue RNA - lung [nTPM]":"10.4","Tissue RNA - lymph node [nTPM]":"1.1","Tissue RNA - medulla oblongata [nTPM]":"8.6","Tissue RNA - midbrain [nTPM]":"7.9","Tissue RNA - ovary [nTPM]":"21.6","Tissue RNA - pancreas [nTPM]":"49.5","Tissue RNA - parathyroid gland [nTPM]":"4.1","Tissue RNA - pituitary gland [nTPM]":"11.8","Tissue RNA - placenta [nTPM]":"1.6","Tissue RNA - pons [nTPM]":"8.8","Tissue RNA - prostate [nTPM]":"19.6","Tissue RNA - rectum [nTPM]":"1.4","Tissue RNA - retina [nTPM]":"1.2","Tissue RNA - salivary gland [nTPM]":"30.1","Tissue RNA - seminal vesicle [nTPM]":"5.5","Tissue RNA - skeletal muscle [nTPM]":"290.1","Tissue RNA - skin 1 [nTPM]":"26.0","Tissue RNA - small intestine [nTPM]":"10.7","Tissue RNA - smooth muscle [nTPM]":"1.1","Tissue RNA - spinal cord [nTPM]":"6.6","Tissue RNA - spleen [nTPM]":"6.5","Tissue RNA - stomach 1 [nTPM]":"27.2","Tissue RNA - testis [nTPM]":"4.7","Tissue RNA - thalamus [nTPM]":"9.1","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"32.0","Tissue RNA - tongue [nTPM]":"58.9","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"17.4","Tissue RNA - vagina [nTPM]":"16.8","Tissue RNA - white matter [nTPM]":"7.4","Cell RNA - A-431 [nTPM]":"12.7","Cell RNA - A549 [nTPM]":"5.7","Cell RNA - AF22 [nTPM]":"1.9","Cell RNA - AN3-CA [nTPM]":"10.2","Cell RNA - ASC diff [nTPM]":"1.7","Cell RNA - ASC TERT1 [nTPM]":"1.0","Cell RNA - BEWO [nTPM]":"10.9","Cell RNA - BJ [nTPM]":"7.5","Cell RNA - BJ hTERT+ [nTPM]":"3.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.1","Cell RNA - CACO-2 [nTPM]":"5.3","Cell RNA - CAPAN-2 [nTPM]":"33.2","Cell RNA - Daudi [nTPM]":"44.9","Cell RNA - EFO-21 [nTPM]":"25.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.6","Cell RNA - GAMG [nTPM]":"2.6","Cell RNA - HaCaT [nTPM]":"29.8","Cell RNA - HAP1 [nTPM]":"1.9","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.6","Cell RNA - HDLM-2 [nTPM]":"3.6","Cell RNA - HEK 293 [nTPM]":"21.9","Cell RNA - HEL [nTPM]":"16.8","Cell RNA - HeLa [nTPM]":"23.3","Cell RNA - Hep G2 [nTPM]":"29.7","Cell RNA - HHSteC [nTPM]":"6.1","Cell RNA - HL-60 [nTPM]":"13.8","Cell RNA - HMC-1 [nTPM]":"1.8","Cell RNA - HSkMC [nTPM]":"2.5","Cell RNA - hTCEpi [nTPM]":"3.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.6","Cell RNA - hTERT-HME1 [nTPM]":"1.7","Cell RNA - hTERT-RPE1 [nTPM]":"4.5","Cell RNA - HUVEC TERT2 [nTPM]":"1.8","Cell RNA - JURKAT [nTPM]":"14.7","Cell RNA - K-562 [nTPM]":"15.2","Cell RNA - Karpas-707 [nTPM]":"8.5","Cell RNA - LHCN-M2 [nTPM]":"1.1","Cell RNA - MCF7 [nTPM]":"73.8","Cell RNA - MOLT-4 [nTPM]":"20.1","Cell RNA - NB-4 [nTPM]":"45.1","Cell RNA - NTERA-2 [nTPM]":"5.5","Cell RNA - OE19 [nTPM]":"4.3","Cell RNA - PC-3 [nTPM]":"24.4","Cell RNA - REH [nTPM]":"18.7","Cell RNA - RH-30 [nTPM]":"11.5","Cell RNA - RPMI-8226 [nTPM]":"145.4","Cell RNA - RPTEC TERT1 [nTPM]":"1.8","Cell RNA - RT4 [nTPM]":"0.7","Cell RNA - SCLC-21H [nTPM]":"15.7","Cell RNA - SH-SY5Y [nTPM]":"31.2","Cell RNA - SiHa [nTPM]":"5.7","Cell RNA - SK-BR-3 [nTPM]":"40.3","Cell RNA - SK-MEL-30 [nTPM]":"41.4","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"29.8","Cell RNA - THP-1 [nTPM]":"1.0","Cell RNA - TIME [nTPM]":"2.9","Cell RNA - U-138 MG [nTPM]":"4.9","Cell RNA - U-2 OS [nTPM]":"7.4","Cell RNA - U-2197 [nTPM]":"7.0","Cell RNA - U-251 MG [nTPM]":"0.8","Cell RNA - U-266\/70 [nTPM]":"17.8","Cell RNA - U-266\/84 [nTPM]":"3.1","Cell RNA - U-698 [nTPM]":"7.4","Cell RNA - U-87 MG [nTPM]":"3.4","Cell RNA - U-937 [nTPM]":"13.4","Cell RNA - WM-115 [nTPM]":"4.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"6.4","Brain RNA - basal ganglia [nTPM]":"5.9","Brain RNA - cerebellum [nTPM]":"6.8","Brain RNA - cerebral cortex [nTPM]":"12.7","Brain RNA - hippocampal formation [nTPM]":"6.4","Brain RNA - hypothalamus [nTPM]":"8.2","Brain RNA - medulla oblongata [nTPM]":"8.6","Brain RNA - midbrain [nTPM]":"7.9","Brain RNA - pons [nTPM]":"8.8","Brain RNA - spinal cord [nTPM]":"6.6","Brain RNA - thalamus [nTPM]":"9.1","Brain RNA - white matter [nTPM]":"7.4","Single Cell Type RNA - Adipocytes [nTPM]":"19.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.6","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"7.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"28.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"39.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"57.5","Single Cell Type RNA - Bipolar cells [nTPM]":"15.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"46.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"45.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"32.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"8.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"42.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"35.6","Single Cell Type RNA - dendritic cells [nTPM]":"1.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"34.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"137.0","Single Cell Type RNA - Ductal cells [nTPM]":"20.8","Single Cell Type RNA - Early spermatids [nTPM]":"7.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.3","Single Cell Type RNA - Endothelial cells [nTPM]":"11.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.9","Single Cell Type RNA - Erythroid cells [nTPM]":"8.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"40.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"16.1","Single Cell Type RNA - Fibroblasts [nTPM]":"15.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"22.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"41.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.7","Single Cell Type RNA - Hepatocytes [nTPM]":"45.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.7","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"55.2","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"6.9","Single Cell Type RNA - Langerhans cells [nTPM]":"5.1","Single Cell Type RNA - Late spermatids [nTPM]":"26.8","Single Cell Type RNA - Leydig cells [nTPM]":"24.8","Single Cell Type RNA - Macrophages [nTPM]":"7.2","Single Cell Type RNA - Melanocytes [nTPM]":"39.2","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"2.4","Single Cell Type RNA - Muller glia cells [nTPM]":"16.9","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.2","Single Cell Type RNA - Paneth cells [nTPM]":"35.2","Single Cell Type RNA - Peritubular cells [nTPM]":"14.3","Single Cell Type RNA - Plasma cells [nTPM]":"12.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"37.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"333.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"20.6","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"55.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.1","Single Cell Type RNA - Spermatocytes [nTPM]":"8.2","Single Cell Type RNA - Spermatogonia [nTPM]":"32.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"46.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"37.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.9","Single Cell Type RNA - T-cells [nTPM]":"6.1","Single Cell Type RNA - Theca cells [nTPM]":"18.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"67.9","Single Cell Type RNA - Urothelial cells [nTPM]":"49.8"},{"Gene":"MAGI2","Gene synonym":["ACVRIP1","AIP1","ARIP1","KIAA0705","MAGI-2"],"Ensembl":"ENSG00000187391","Gene description":"Membrane associated guanylate kinase, WW and PDZ domain containing 2","Uniprot":["Q86UL8"],"Chromosome":"7","Position":"78017055-79453667","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Neurogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"27.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Astrocytes":"1765.2","Excitatory neurons":"2453.9","Inhibitory neurons":"2438.2","Oligodendrocyte precursor cells":"1208.9","Oligodendrocytes":"4001.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"7.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Karpas-707":"81.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013650"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA013650":"AB_1853501"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.08e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.0","Tissue RNA - adrenal gland [nTPM]":"5.9","Tissue RNA - amygdala [nTPM]":"11.9","Tissue RNA - appendix [nTPM]":"1.1","Tissue RNA - basal ganglia [nTPM]":"16.4","Tissue RNA - bone marrow [nTPM]":"0.8","Tissue RNA - breast [nTPM]":"3.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"27.1","Tissue RNA - cervix [nTPM]":"4.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"3.8","Tissue RNA - duodenum [nTPM]":"1.8","Tissue RNA - endometrium 1 [nTPM]":"4.1","Tissue RNA - epididymis [nTPM]":"3.6","Tissue RNA - esophagus [nTPM]":"2.1","Tissue RNA - fallopian tube [nTPM]":"3.9","Tissue RNA - gallbladder [nTPM]":"3.0","Tissue RNA - heart muscle [nTPM]":"2.6","Tissue RNA - hippocampal formation [nTPM]":"14.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"5.3","Tissue RNA - liver [nTPM]":"1.4","Tissue RNA - lung [nTPM]":"2.8","Tissue RNA - lymph node [nTPM]":"0.7","Tissue RNA - medulla oblongata [nTPM]":"0.7","Tissue RNA - midbrain [nTPM]":"1.3","Tissue RNA - ovary [nTPM]":"8.2","Tissue RNA - pancreas [nTPM]":"3.3","Tissue RNA - parathyroid gland [nTPM]":"12.5","Tissue RNA - pituitary gland [nTPM]":"6.9","Tissue RNA - placenta [nTPM]":"1.2","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"8.5","Tissue RNA - rectum [nTPM]":"1.6","Tissue RNA - retina [nTPM]":"11.6","Tissue RNA - salivary gland [nTPM]":"1.6","Tissue RNA - seminal vesicle [nTPM]":"8.1","Tissue RNA - skeletal muscle [nTPM]":"1.9","Tissue RNA - skin 1 [nTPM]":"1.3","Tissue RNA - small intestine [nTPM]":"2.0","Tissue RNA - smooth muscle [nTPM]":"2.5","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"1.9","Tissue RNA - stomach 1 [nTPM]":"2.2","Tissue RNA - testis [nTPM]":"3.6","Tissue RNA - thalamus [nTPM]":"10.8","Tissue RNA - thymus [nTPM]":"0.6","Tissue RNA - thyroid gland [nTPM]":"6.5","Tissue RNA - tongue [nTPM]":"2.3","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"4.4","Tissue RNA - vagina [nTPM]":"3.0","Tissue RNA - white matter [nTPM]":"17.0","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.6","Cell RNA - AF22 [nTPM]":"19.5","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"4.0","Cell RNA - ASC TERT1 [nTPM]":"6.2","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"3.5","Cell RNA - BJ hTERT+ [nTPM]":"6.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"2.2","Cell RNA - GAMG [nTPM]":"2.6","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"1.1","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.9","Cell RNA - HDLM-2 [nTPM]":"1.0","Cell RNA - HEK 293 [nTPM]":"0.8","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"1.1","Cell RNA - HHSteC [nTPM]":"5.8","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"1.0","Cell RNA - HSkMC [nTPM]":"4.7","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.4","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"3.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.9","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.6","Cell RNA - Karpas-707 [nTPM]":"81.9","Cell RNA - LHCN-M2 [nTPM]":"1.7","Cell RNA - MCF7 [nTPM]":"0.8","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"4.3","Cell RNA - OE19 [nTPM]":"0.7","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"1.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"2.9","Cell RNA - SH-SY5Y [nTPM]":"4.9","Cell RNA - SiHa [nTPM]":"0.8","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"1.9","Cell RNA - SuSa [nTPM]":"2.9","Cell RNA - T-47d [nTPM]":"0.4","Cell RNA - THP-1 [nTPM]":"0.6","Cell RNA - TIME [nTPM]":"1.1","Cell RNA - U-138 MG [nTPM]":"2.8","Cell RNA - U-2 OS [nTPM]":"1.0","Cell RNA - U-2197 [nTPM]":"7.6","Cell RNA - U-251 MG [nTPM]":"0.5","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"1.8","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"1.2","Blood RNA - basophil [nTPM]":"0.8","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"11.9","Brain RNA - basal ganglia [nTPM]":"16.4","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"27.1","Brain RNA - hippocampal formation [nTPM]":"14.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.7","Brain RNA - midbrain [nTPM]":"1.3","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"10.8","Brain RNA - white matter [nTPM]":"17.0","Single Cell Type RNA - Adipocytes [nTPM]":"7.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.5","Single Cell Type RNA - Astrocytes [nTPM]":"1765.2","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"29.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"3.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"25.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.3","Single Cell Type RNA - Endothelial cells [nTPM]":"5.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2453.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"11.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"11.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"2.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2438.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"32.5","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"327.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"24.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1208.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4001.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"1.5","Single Cell Type RNA - Peritubular cells [nTPM]":"19.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.3","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.8","Single Cell Type RNA - Spermatocytes [nTPM]":"4.8","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"0.7","Single Cell Type RNA - Theca cells [nTPM]":"8.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.4","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"MAGT1","Gene synonym":["DKFZp564K142","IAP","MRX95","OST3B","SLC58A1"],"Ensembl":"ENSG00000102158","Gene description":"Magnesium transporter 1","Uniprot":["Q9H0U3"],"Chromosome":"X","Position":"77825747-77895593","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"145.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049851"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049851":"AB_2680913"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.30e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.98e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.55e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Tissue RNA - adipose tissue [nTPM]":"25.3","Tissue RNA - adrenal gland [nTPM]":"22.6","Tissue RNA - amygdala [nTPM]":"12.9","Tissue RNA - appendix [nTPM]":"24.2","Tissue RNA - basal ganglia [nTPM]":"19.4","Tissue RNA - bone marrow [nTPM]":"20.8","Tissue RNA - breast [nTPM]":"36.5","Tissue RNA - cerebellum [nTPM]":"17.2","Tissue RNA - cerebral cortex [nTPM]":"17.4","Tissue RNA - cervix [nTPM]":"39.4","Tissue RNA - choroid plexus [nTPM]":"14.4","Tissue RNA - colon [nTPM]":"28.3","Tissue RNA - duodenum [nTPM]":"25.7","Tissue RNA - endometrium 1 [nTPM]":"27.5","Tissue RNA - epididymis [nTPM]":"53.7","Tissue RNA - esophagus [nTPM]":"25.6","Tissue RNA - fallopian tube [nTPM]":"25.9","Tissue RNA - gallbladder [nTPM]":"25.1","Tissue RNA - heart muscle [nTPM]":"37.5","Tissue RNA - hippocampal formation [nTPM]":"13.0","Tissue RNA - hypothalamus [nTPM]":"16.4","Tissue RNA - kidney [nTPM]":"41.9","Tissue RNA - liver [nTPM]":"71.2","Tissue RNA - lung [nTPM]":"26.8","Tissue RNA - lymph node [nTPM]":"22.5","Tissue RNA - medulla oblongata [nTPM]":"20.9","Tissue RNA - midbrain [nTPM]":"18.5","Tissue RNA - ovary [nTPM]":"23.6","Tissue RNA - pancreas [nTPM]":"31.9","Tissue RNA - parathyroid gland [nTPM]":"38.4","Tissue RNA - pituitary gland [nTPM]":"18.5","Tissue RNA - placenta [nTPM]":"36.4","Tissue RNA - pons [nTPM]":"21.9","Tissue RNA - prostate [nTPM]":"33.5","Tissue RNA - rectum [nTPM]":"27.0","Tissue RNA - retina [nTPM]":"5.2","Tissue RNA - salivary gland [nTPM]":"34.6","Tissue RNA - seminal vesicle [nTPM]":"28.0","Tissue RNA - skeletal muscle [nTPM]":"17.1","Tissue RNA - skin 1 [nTPM]":"18.3","Tissue RNA - small intestine [nTPM]":"26.2","Tissue RNA - smooth muscle [nTPM]":"24.3","Tissue RNA - spinal cord [nTPM]":"16.6","Tissue RNA - spleen [nTPM]":"23.5","Tissue RNA - stomach 1 [nTPM]":"29.4","Tissue RNA - testis [nTPM]":"11.3","Tissue RNA - thalamus [nTPM]":"17.9","Tissue RNA - thymus [nTPM]":"21.0","Tissue RNA - thyroid gland [nTPM]":"78.0","Tissue RNA - tongue [nTPM]":"21.9","Tissue RNA - tonsil [nTPM]":"23.5","Tissue RNA - urinary bladder [nTPM]":"29.1","Tissue RNA - vagina [nTPM]":"18.2","Tissue RNA - white matter [nTPM]":"27.0","Cell RNA - A-431 [nTPM]":"62.5","Cell RNA - A549 [nTPM]":"34.1","Cell RNA - AF22 [nTPM]":"41.7","Cell RNA - AN3-CA [nTPM]":"48.8","Cell RNA - ASC diff [nTPM]":"75.0","Cell RNA - ASC TERT1 [nTPM]":"49.3","Cell RNA - BEWO [nTPM]":"64.8","Cell RNA - BJ [nTPM]":"66.9","Cell RNA - BJ hTERT+ [nTPM]":"67.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"51.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"56.5","Cell RNA - CACO-2 [nTPM]":"45.6","Cell RNA - CAPAN-2 [nTPM]":"99.5","Cell RNA - Daudi [nTPM]":"45.6","Cell RNA - EFO-21 [nTPM]":"90.9","Cell RNA - fHDF\/TERT166 [nTPM]":"71.7","Cell RNA - GAMG [nTPM]":"53.3","Cell RNA - HaCaT [nTPM]":"56.4","Cell RNA - HAP1 [nTPM]":"88.4","Cell RNA - HBEC3-KT [nTPM]":"50.8","Cell RNA - HBF TERT88 [nTPM]":"80.0","Cell RNA - HDLM-2 [nTPM]":"32.3","Cell RNA - HEK 293 [nTPM]":"55.4","Cell RNA - HEL [nTPM]":"30.6","Cell RNA - HeLa [nTPM]":"46.2","Cell RNA - Hep G2 [nTPM]":"42.5","Cell RNA - HHSteC [nTPM]":"66.6","Cell RNA - HL-60 [nTPM]":"64.9","Cell RNA - HMC-1 [nTPM]":"31.1","Cell RNA - HSkMC [nTPM]":"45.3","Cell RNA - hTCEpi [nTPM]":"43.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"64.6","Cell RNA - hTERT-HME1 [nTPM]":"56.7","Cell RNA - hTERT-RPE1 [nTPM]":"55.1","Cell RNA - HUVEC TERT2 [nTPM]":"74.0","Cell RNA - JURKAT [nTPM]":"31.2","Cell RNA - K-562 [nTPM]":"36.5","Cell RNA - Karpas-707 [nTPM]":"123.2","Cell RNA - LHCN-M2 [nTPM]":"64.7","Cell RNA - MCF7 [nTPM]":"40.4","Cell RNA - MOLT-4 [nTPM]":"36.2","Cell RNA - NB-4 [nTPM]":"23.9","Cell RNA - NTERA-2 [nTPM]":"56.1","Cell RNA - OE19 [nTPM]":"64.6","Cell RNA - PC-3 [nTPM]":"41.3","Cell RNA - REH [nTPM]":"43.3","Cell RNA - RH-30 [nTPM]":"72.5","Cell RNA - RPMI-8226 [nTPM]":"84.7","Cell RNA - RPTEC TERT1 [nTPM]":"61.9","Cell RNA - RT4 [nTPM]":"45.8","Cell RNA - SCLC-21H [nTPM]":"14.1","Cell RNA - SH-SY5Y [nTPM]":"26.3","Cell RNA - SiHa [nTPM]":"91.6","Cell RNA - SK-BR-3 [nTPM]":"64.8","Cell RNA - SK-MEL-30 [nTPM]":"58.0","Cell RNA - SuSa [nTPM]":"43.6","Cell RNA - T-47d [nTPM]":"43.8","Cell RNA - THP-1 [nTPM]":"35.3","Cell RNA - TIME [nTPM]":"75.2","Cell RNA - U-138 MG [nTPM]":"45.6","Cell RNA - U-2 OS [nTPM]":"51.1","Cell RNA - U-2197 [nTPM]":"71.7","Cell RNA - U-251 MG [nTPM]":"33.2","Cell RNA - U-266\/70 [nTPM]":"44.8","Cell RNA - U-266\/84 [nTPM]":"103.1","Cell RNA - U-698 [nTPM]":"58.1","Cell RNA - U-87 MG [nTPM]":"49.7","Cell RNA - U-937 [nTPM]":"60.5","Cell RNA - WM-115 [nTPM]":"61.0","Blood RNA - basophil [nTPM]":"15.3","Blood RNA - classical monocyte [nTPM]":"12.9","Blood RNA - eosinophil [nTPM]":"13.7","Blood RNA - gdT-cell [nTPM]":"17.2","Blood RNA - intermediate monocyte [nTPM]":"19.7","Blood RNA - MAIT T-cell [nTPM]":"18.4","Blood RNA - memory B-cell [nTPM]":"12.5","Blood RNA - memory CD4 T-cell [nTPM]":"15.6","Blood RNA - memory CD8 T-cell [nTPM]":"16.6","Blood RNA - myeloid DC [nTPM]":"11.1","Blood RNA - naive B-cell [nTPM]":"10.7","Blood RNA - naive CD4 T-cell [nTPM]":"14.9","Blood RNA - naive CD8 T-cell [nTPM]":"17.7","Blood RNA - neutrophil [nTPM]":"11.0","Blood RNA - NK-cell [nTPM]":"18.6","Blood RNA - non-classical monocyte [nTPM]":"21.0","Blood RNA - plasmacytoid DC [nTPM]":"22.2","Blood RNA - T-reg [nTPM]":"12.8","Blood RNA - total PBMC [nTPM]":"15.7","Brain RNA - amygdala [nTPM]":"12.9","Brain RNA - basal ganglia [nTPM]":"19.4","Brain RNA - cerebellum [nTPM]":"17.2","Brain RNA - cerebral cortex [nTPM]":"17.4","Brain RNA - hippocampal formation [nTPM]":"13.0","Brain RNA - hypothalamus [nTPM]":"16.4","Brain RNA - medulla oblongata [nTPM]":"20.9","Brain RNA - midbrain [nTPM]":"18.5","Brain RNA - pons [nTPM]":"21.9","Brain RNA - spinal cord [nTPM]":"16.6","Brain RNA - thalamus [nTPM]":"17.9","Brain RNA - white matter [nTPM]":"27.0","Single Cell Type RNA - Adipocytes [nTPM]":"50.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"53.6","Single Cell Type RNA - Astrocytes [nTPM]":"9.8","Single Cell Type RNA - B-cells [nTPM]":"37.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"33.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"55.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"51.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"5.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"39.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"25.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"53.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"42.9","Single Cell Type RNA - Club cells [nTPM]":"51.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"33.3","Single Cell Type RNA - dendritic cells [nTPM]":"43.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"35.3","Single Cell Type RNA - Early spermatids [nTPM]":"2.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"38.9","Single Cell Type RNA - Endothelial cells [nTPM]":"40.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.7","Single Cell Type RNA - Erythroid cells [nTPM]":"33.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"34.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"59.3","Single Cell Type RNA - Fibroblasts [nTPM]":"43.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"33.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"58.0","Single Cell Type RNA - granulocytes [nTPM]":"30.4","Single Cell Type RNA - Granulosa cells [nTPM]":"24.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"43.2","Single Cell Type RNA - Hepatocytes [nTPM]":"145.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"42.3","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"39.6","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"49.8","Single Cell Type RNA - Langerhans cells [nTPM]":"46.1","Single Cell Type RNA - Late spermatids [nTPM]":"2.5","Single Cell Type RNA - Leydig cells [nTPM]":"30.7","Single Cell Type RNA - Macrophages [nTPM]":"45.1","Single Cell Type RNA - Melanocytes [nTPM]":"33.8","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"33.9","Single Cell Type RNA - Muller glia cells [nTPM]":"17.1","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"28.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"36.2","Single Cell Type RNA - Paneth cells [nTPM]":"37.2","Single Cell Type RNA - Peritubular cells [nTPM]":"27.1","Single Cell Type RNA - Plasma cells [nTPM]":"87.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"65.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"31.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"32.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.2","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"38.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"31.2","Single Cell Type RNA - Spermatocytes [nTPM]":"6.6","Single Cell Type RNA - Spermatogonia [nTPM]":"16.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"36.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"45.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"81.3","Single Cell Type RNA - T-cells [nTPM]":"36.0","Single Cell Type RNA - Theca cells [nTPM]":"31.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.0","Single Cell Type RNA - Urothelial cells [nTPM]":"69.4"},{"Gene":"MAK","Gene synonym":["dJ417M14.2","RP62"],"Ensembl":"ENSG00000111837","Gene description":"Male germ cell associated kinase","Uniprot":["P20794"],"Chromosome":"6","Position":"10762723-10838553","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Differentiation","Spermatogenesis","Transcription","Transcription regulation"],"Molecular function":["Developmental protein","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"22","RNA tissue specific nTPM":{"retina":"118.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"369.1","Early spermatids":"119.7","Rod photoreceptor cells":"330.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"neutrophil":"6.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"6.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"1.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.77e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.71e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"1.5","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"5.4","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"5.4","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.7","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.7","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"4.6","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"118.9","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.7","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"4.7","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"0.7","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"1.3","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"6.3","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"1.5","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.7","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"2.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.4","Single Cell Type RNA - Astrocytes [nTPM]":"16.3","Single Cell Type RNA - B-cells [nTPM]":"1.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"14.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"5.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"369.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"119.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"43.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.7","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"45.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.8","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"39.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"47.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"1.3","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"1.3","Single Cell Type RNA - Muller glia cells [nTPM]":"23.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"30.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"1.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"48.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"330.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.5","Single Cell Type RNA - Spermatocytes [nTPM]":"15.2","Single Cell Type RNA - Spermatogonia [nTPM]":"5.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"MALT1","Gene synonym":["MLT","PCASP1"],"Ensembl":"ENSG00000172175","Gene description":"MALT1 paracaspase","Uniprot":["Q9UDY8"],"Chromosome":"18","Position":"58671465-58754477","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Immunity","Ubl conjugation pathway"],"Molecular function":["Hydrolase","Protease"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RPTEC TERT1":"88.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004494","HPA048432"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 65: Plasmacytoid DCs - Unknown function","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB004494":"AB_627909","HPA048432":"AB_2680389"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.1","Tissue RNA - adrenal gland [nTPM]":"2.5","Tissue RNA - amygdala [nTPM]":"2.9","Tissue RNA - appendix [nTPM]":"11.2","Tissue RNA - basal ganglia [nTPM]":"2.8","Tissue RNA - bone marrow [nTPM]":"10.5","Tissue RNA - breast [nTPM]":"6.3","Tissue RNA - cerebellum [nTPM]":"4.8","Tissue RNA - cerebral cortex [nTPM]":"3.6","Tissue RNA - cervix [nTPM]":"7.7","Tissue RNA - choroid plexus [nTPM]":"4.2","Tissue RNA - colon [nTPM]":"5.1","Tissue RNA - duodenum [nTPM]":"3.6","Tissue RNA - endometrium 1 [nTPM]":"5.4","Tissue RNA - epididymis [nTPM]":"4.2","Tissue RNA - esophagus [nTPM]":"12.5","Tissue RNA - fallopian tube [nTPM]":"5.1","Tissue RNA - gallbladder [nTPM]":"5.8","Tissue RNA - heart muscle [nTPM]":"5.4","Tissue RNA - hippocampal formation [nTPM]":"3.1","Tissue RNA - hypothalamus [nTPM]":"4.1","Tissue RNA - kidney [nTPM]":"6.7","Tissue RNA - liver [nTPM]":"6.9","Tissue RNA - lung [nTPM]":"7.3","Tissue RNA - lymph node [nTPM]":"21.1","Tissue RNA - medulla oblongata [nTPM]":"3.2","Tissue RNA - midbrain [nTPM]":"2.6","Tissue RNA - ovary [nTPM]":"5.3","Tissue RNA - pancreas [nTPM]":"4.0","Tissue RNA - parathyroid gland [nTPM]":"5.3","Tissue RNA - pituitary gland [nTPM]":"4.7","Tissue RNA - placenta [nTPM]":"4.0","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"11.5","Tissue RNA - rectum [nTPM]":"5.5","Tissue RNA - retina [nTPM]":"8.7","Tissue RNA - salivary gland [nTPM]":"5.8","Tissue RNA - seminal vesicle [nTPM]":"3.8","Tissue RNA - skeletal muscle [nTPM]":"8.3","Tissue RNA - skin 1 [nTPM]":"9.4","Tissue RNA - small intestine [nTPM]":"7.7","Tissue RNA - smooth muscle [nTPM]":"4.2","Tissue RNA - spinal cord [nTPM]":"3.0","Tissue RNA - spleen [nTPM]":"11.5","Tissue RNA - stomach 1 [nTPM]":"4.6","Tissue RNA - testis [nTPM]":"8.2","Tissue RNA - thalamus [nTPM]":"4.1","Tissue RNA - thymus [nTPM]":"15.6","Tissue RNA - thyroid gland [nTPM]":"5.3","Tissue RNA - tongue [nTPM]":"2.8","Tissue RNA - tonsil [nTPM]":"23.1","Tissue RNA - urinary bladder [nTPM]":"7.1","Tissue RNA - vagina [nTPM]":"9.6","Tissue RNA - white matter [nTPM]":"3.6","Cell RNA - A-431 [nTPM]":"11.4","Cell RNA - A549 [nTPM]":"16.0","Cell RNA - AF22 [nTPM]":"16.8","Cell RNA - AN3-CA [nTPM]":"5.2","Cell RNA - ASC diff [nTPM]":"3.1","Cell RNA - ASC TERT1 [nTPM]":"6.7","Cell RNA - BEWO [nTPM]":"9.2","Cell RNA - BJ [nTPM]":"19.7","Cell RNA - BJ hTERT+ [nTPM]":"12.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.6","Cell RNA - CACO-2 [nTPM]":"13.8","Cell RNA - CAPAN-2 [nTPM]":"13.5","Cell RNA - Daudi [nTPM]":"27.0","Cell RNA - EFO-21 [nTPM]":"10.3","Cell RNA - fHDF\/TERT166 [nTPM]":"24.0","Cell RNA - GAMG [nTPM]":"11.1","Cell RNA - HaCaT [nTPM]":"12.0","Cell RNA - HAP1 [nTPM]":"10.8","Cell RNA - HBEC3-KT [nTPM]":"7.6","Cell RNA - HBF TERT88 [nTPM]":"20.8","Cell RNA - HDLM-2 [nTPM]":"17.0","Cell RNA - HEK 293 [nTPM]":"6.8","Cell RNA - HEL [nTPM]":"9.7","Cell RNA - HeLa [nTPM]":"9.0","Cell RNA - Hep G2 [nTPM]":"21.8","Cell RNA - HHSteC [nTPM]":"4.0","Cell RNA - HL-60 [nTPM]":"20.1","Cell RNA - HMC-1 [nTPM]":"11.4","Cell RNA - HSkMC [nTPM]":"4.0","Cell RNA - hTCEpi [nTPM]":"12.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.8","Cell RNA - hTERT-HME1 [nTPM]":"10.4","Cell RNA - hTERT-RPE1 [nTPM]":"6.6","Cell RNA - HUVEC TERT2 [nTPM]":"3.4","Cell RNA - JURKAT [nTPM]":"7.7","Cell RNA - K-562 [nTPM]":"15.3","Cell RNA - Karpas-707 [nTPM]":"42.3","Cell RNA - LHCN-M2 [nTPM]":"9.6","Cell RNA - MCF7 [nTPM]":"3.3","Cell RNA - MOLT-4 [nTPM]":"4.7","Cell RNA - NB-4 [nTPM]":"9.7","Cell RNA - NTERA-2 [nTPM]":"6.3","Cell RNA - OE19 [nTPM]":"4.1","Cell RNA - PC-3 [nTPM]":"7.1","Cell RNA - REH [nTPM]":"14.8","Cell RNA - RH-30 [nTPM]":"11.5","Cell RNA - RPMI-8226 [nTPM]":"19.7","Cell RNA - RPTEC TERT1 [nTPM]":"88.9","Cell RNA - RT4 [nTPM]":"2.8","Cell RNA - SCLC-21H [nTPM]":"2.5","Cell RNA - SH-SY5Y [nTPM]":"4.5","Cell RNA - SiHa [nTPM]":"11.7","Cell RNA - SK-BR-3 [nTPM]":"6.0","Cell RNA - SK-MEL-30 [nTPM]":"9.3","Cell RNA - SuSa [nTPM]":"12.0","Cell RNA - T-47d [nTPM]":"5.1","Cell RNA - THP-1 [nTPM]":"12.2","Cell RNA - TIME [nTPM]":"5.7","Cell RNA - U-138 MG [nTPM]":"22.6","Cell RNA - U-2 OS [nTPM]":"9.1","Cell RNA - U-2197 [nTPM]":"7.1","Cell RNA - U-251 MG [nTPM]":"20.8","Cell RNA - U-266\/70 [nTPM]":"38.5","Cell RNA - U-266\/84 [nTPM]":"54.4","Cell RNA - U-698 [nTPM]":"16.3","Cell RNA - U-87 MG [nTPM]":"10.6","Cell RNA - U-937 [nTPM]":"15.6","Cell RNA - WM-115 [nTPM]":"9.9","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"1.1","Blood RNA - memory CD4 T-cell [nTPM]":"1.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.8","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"2.9","Brain RNA - basal ganglia [nTPM]":"2.8","Brain RNA - cerebellum [nTPM]":"4.8","Brain RNA - cerebral cortex [nTPM]":"3.6","Brain RNA - hippocampal formation [nTPM]":"3.1","Brain RNA - hypothalamus [nTPM]":"4.1","Brain RNA - medulla oblongata [nTPM]":"3.2","Brain RNA - midbrain [nTPM]":"2.6","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"3.0","Brain RNA - thalamus [nTPM]":"4.1","Brain RNA - white matter [nTPM]":"3.6","Single Cell Type RNA - Adipocytes [nTPM]":"35.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.2","Single Cell Type RNA - Astrocytes [nTPM]":"24.2","Single Cell Type RNA - B-cells [nTPM]":"67.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"33.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.2","Single Cell Type RNA - Bipolar cells [nTPM]":"14.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"7.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"85.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.2","Single Cell Type RNA - dendritic cells [nTPM]":"53.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"16.6","Single Cell Type RNA - Early spermatids [nTPM]":"12.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.5","Single Cell Type RNA - Endothelial cells [nTPM]":"31.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"61.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.0","Single Cell Type RNA - Fibroblasts [nTPM]":"15.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.7","Single Cell Type RNA - granulocytes [nTPM]":"31.7","Single Cell Type RNA - Granulosa cells [nTPM]":"28.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.4","Single Cell Type RNA - Hepatocytes [nTPM]":"11.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.8","Single Cell Type RNA - Horizontal cells [nTPM]":"55.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"42.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.6","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"21.0","Single Cell Type RNA - Langerhans cells [nTPM]":"96.5","Single Cell Type RNA - Late spermatids [nTPM]":"8.0","Single Cell Type RNA - Leydig cells [nTPM]":"10.2","Single Cell Type RNA - Macrophages [nTPM]":"55.9","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"34.7","Single Cell Type RNA - monocytes [nTPM]":"79.5","Single Cell Type RNA - Muller glia cells [nTPM]":"26.2","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"52.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.2","Single Cell Type RNA - Paneth cells [nTPM]":"21.9","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"42.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"46.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"30.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.1","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.9","Single Cell Type RNA - Spermatocytes [nTPM]":"40.1","Single Cell Type RNA - Spermatogonia [nTPM]":"35.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.0","Single Cell Type RNA - T-cells [nTPM]":"55.2","Single Cell Type RNA - Theca cells [nTPM]":"5.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.7","Single Cell Type RNA - Urothelial cells [nTPM]":"38.1"},{"Gene":"MAN1B1","Gene synonym":["ERManI","MANA-ER","MRT15"],"Ensembl":"ENSG00000177239","Gene description":"Mannosidase alpha class 1B member 1","Uniprot":["Q9UKM7"],"Chromosome":"9","Position":"137086985-137109183","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051516"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"940000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA051516":"AB_2681518"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.45e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-3"},"Tissue RNA - adipose tissue [nTPM]":"25.3","Tissue RNA - adrenal gland [nTPM]":"32.2","Tissue RNA - amygdala [nTPM]":"21.3","Tissue RNA - appendix [nTPM]":"12.1","Tissue RNA - basal ganglia [nTPM]":"21.2","Tissue RNA - bone marrow [nTPM]":"9.1","Tissue RNA - breast [nTPM]":"25.1","Tissue RNA - cerebellum [nTPM]":"21.1","Tissue RNA - cerebral cortex [nTPM]":"32.9","Tissue RNA - cervix [nTPM]":"22.6","Tissue RNA - choroid plexus [nTPM]":"26.3","Tissue RNA - colon [nTPM]":"24.1","Tissue RNA - duodenum [nTPM]":"15.5","Tissue RNA - endometrium 1 [nTPM]":"20.7","Tissue RNA - epididymis [nTPM]":"20.4","Tissue RNA - esophagus [nTPM]":"32.1","Tissue RNA - fallopian tube [nTPM]":"22.0","Tissue RNA - gallbladder [nTPM]":"20.1","Tissue RNA - heart muscle [nTPM]":"27.3","Tissue RNA - hippocampal formation [nTPM]":"22.4","Tissue RNA - hypothalamus [nTPM]":"23.1","Tissue RNA - kidney [nTPM]":"31.8","Tissue RNA - liver [nTPM]":"39.6","Tissue RNA - lung [nTPM]":"23.0","Tissue RNA - lymph node [nTPM]":"15.4","Tissue RNA - medulla oblongata [nTPM]":"22.6","Tissue RNA - midbrain [nTPM]":"22.7","Tissue RNA - ovary [nTPM]":"28.0","Tissue RNA - pancreas [nTPM]":"36.0","Tissue RNA - parathyroid gland [nTPM]":"20.0","Tissue RNA - pituitary gland [nTPM]":"32.6","Tissue RNA - placenta [nTPM]":"21.4","Tissue RNA - pons [nTPM]":"25.2","Tissue RNA - prostate [nTPM]":"26.1","Tissue RNA - rectum [nTPM]":"9.9","Tissue RNA - retina [nTPM]":"3.6","Tissue RNA - salivary gland [nTPM]":"34.2","Tissue RNA - seminal vesicle [nTPM]":"15.2","Tissue RNA - skeletal muscle [nTPM]":"17.6","Tissue RNA - skin 1 [nTPM]":"32.6","Tissue RNA - small intestine [nTPM]":"22.9","Tissue RNA - smooth muscle [nTPM]":"12.1","Tissue RNA - spinal cord [nTPM]":"21.7","Tissue RNA - spleen [nTPM]":"28.7","Tissue RNA - stomach 1 [nTPM]":"25.6","Tissue RNA - testis [nTPM]":"28.3","Tissue RNA - thalamus [nTPM]":"22.9","Tissue RNA - thymus [nTPM]":"13.8","Tissue RNA - thyroid gland [nTPM]":"27.1","Tissue RNA - tongue [nTPM]":"9.9","Tissue RNA - tonsil [nTPM]":"10.1","Tissue RNA - urinary bladder [nTPM]":"22.0","Tissue RNA - vagina [nTPM]":"21.9","Tissue RNA - white matter [nTPM]":"22.8","Cell RNA - A-431 [nTPM]":"22.8","Cell RNA - A549 [nTPM]":"50.7","Cell RNA - AF22 [nTPM]":"18.2","Cell RNA - AN3-CA [nTPM]":"49.9","Cell RNA - ASC diff [nTPM]":"67.0","Cell RNA - ASC TERT1 [nTPM]":"57.7","Cell RNA - BEWO [nTPM]":"57.0","Cell RNA - BJ [nTPM]":"37.9","Cell RNA - BJ hTERT+ [nTPM]":"78.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"48.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"43.7","Cell RNA - CACO-2 [nTPM]":"24.9","Cell RNA - CAPAN-2 [nTPM]":"67.4","Cell RNA - Daudi [nTPM]":"20.0","Cell RNA - EFO-21 [nTPM]":"118.8","Cell RNA - fHDF\/TERT166 [nTPM]":"64.7","Cell RNA - GAMG [nTPM]":"69.2","Cell RNA - HaCaT [nTPM]":"74.3","Cell RNA - HAP1 [nTPM]":"11.0","Cell RNA - HBEC3-KT [nTPM]":"36.3","Cell RNA - HBF TERT88 [nTPM]":"9.1","Cell RNA - HDLM-2 [nTPM]":"27.7","Cell RNA - HEK 293 [nTPM]":"17.3","Cell RNA - HEL [nTPM]":"8.7","Cell RNA - HeLa [nTPM]":"41.2","Cell RNA - Hep G2 [nTPM]":"33.2","Cell RNA - HHSteC [nTPM]":"59.6","Cell RNA - HL-60 [nTPM]":"16.0","Cell RNA - HMC-1 [nTPM]":"33.1","Cell RNA - HSkMC [nTPM]":"65.1","Cell RNA - hTCEpi [nTPM]":"66.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"29.1","Cell RNA - hTERT-HME1 [nTPM]":"25.1","Cell RNA - hTERT-RPE1 [nTPM]":"67.1","Cell RNA - HUVEC TERT2 [nTPM]":"32.4","Cell RNA - JURKAT [nTPM]":"26.5","Cell RNA - K-562 [nTPM]":"24.5","Cell RNA - Karpas-707 [nTPM]":"32.7","Cell RNA - LHCN-M2 [nTPM]":"36.4","Cell RNA - MCF7 [nTPM]":"45.0","Cell RNA - MOLT-4 [nTPM]":"16.7","Cell RNA - NB-4 [nTPM]":"37.8","Cell RNA - NTERA-2 [nTPM]":"23.5","Cell RNA - OE19 [nTPM]":"67.3","Cell RNA - PC-3 [nTPM]":"50.0","Cell RNA - REH [nTPM]":"9.7","Cell RNA - RH-30 [nTPM]":"30.6","Cell RNA - RPMI-8226 [nTPM]":"63.9","Cell RNA - RPTEC TERT1 [nTPM]":"41.6","Cell RNA - RT4 [nTPM]":"11.3","Cell RNA - SCLC-21H [nTPM]":"20.4","Cell RNA - SH-SY5Y [nTPM]":"18.3","Cell RNA - SiHa [nTPM]":"55.2","Cell RNA - SK-BR-3 [nTPM]":"55.9","Cell RNA - SK-MEL-30 [nTPM]":"38.7","Cell RNA - SuSa [nTPM]":"9.6","Cell RNA - T-47d [nTPM]":"63.5","Cell RNA - THP-1 [nTPM]":"31.5","Cell RNA - TIME [nTPM]":"46.5","Cell RNA - U-138 MG [nTPM]":"69.6","Cell RNA - U-2 OS [nTPM]":"25.9","Cell RNA - U-2197 [nTPM]":"52.9","Cell RNA - U-251 MG [nTPM]":"43.6","Cell RNA - U-266\/70 [nTPM]":"13.0","Cell RNA - U-266\/84 [nTPM]":"11.1","Cell RNA - U-698 [nTPM]":"13.3","Cell RNA - U-87 MG [nTPM]":"84.6","Cell RNA - U-937 [nTPM]":"19.9","Cell RNA - WM-115 [nTPM]":"61.6","Blood RNA - basophil [nTPM]":"17.9","Blood RNA - classical monocyte [nTPM]":"31.2","Blood RNA - eosinophil [nTPM]":"27.0","Blood RNA - gdT-cell [nTPM]":"32.4","Blood RNA - intermediate monocyte [nTPM]":"34.4","Blood RNA - MAIT T-cell [nTPM]":"30.2","Blood RNA - memory B-cell [nTPM]":"19.1","Blood RNA - memory CD4 T-cell [nTPM]":"25.1","Blood RNA - memory CD8 T-cell [nTPM]":"30.4","Blood RNA - myeloid DC [nTPM]":"36.0","Blood RNA - naive B-cell [nTPM]":"16.4","Blood RNA - naive CD4 T-cell [nTPM]":"24.3","Blood RNA - naive CD8 T-cell [nTPM]":"25.0","Blood RNA - neutrophil [nTPM]":"9.0","Blood RNA - NK-cell [nTPM]":"31.0","Blood RNA - non-classical monocyte [nTPM]":"42.2","Blood RNA - plasmacytoid DC [nTPM]":"26.6","Blood RNA - T-reg [nTPM]":"34.5","Blood RNA - total PBMC [nTPM]":"32.1","Brain RNA - amygdala [nTPM]":"21.3","Brain RNA - basal ganglia [nTPM]":"21.2","Brain RNA - cerebellum [nTPM]":"21.1","Brain RNA - cerebral cortex [nTPM]":"32.9","Brain RNA - hippocampal formation [nTPM]":"22.4","Brain RNA - hypothalamus [nTPM]":"23.1","Brain RNA - medulla oblongata [nTPM]":"22.6","Brain RNA - midbrain [nTPM]":"22.7","Brain RNA - pons [nTPM]":"25.2","Brain RNA - spinal cord [nTPM]":"21.7","Brain RNA - thalamus [nTPM]":"22.9","Brain RNA - white matter [nTPM]":"22.8","Single Cell Type RNA - Adipocytes [nTPM]":"18.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.3","Single Cell Type RNA - Astrocytes [nTPM]":"23.5","Single Cell Type RNA - B-cells [nTPM]":"18.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"33.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.0","Single Cell Type RNA - Bipolar cells [nTPM]":"20.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"21.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"53.2","Single Cell Type RNA - dendritic cells [nTPM]":"24.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"39.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"32.0","Single Cell Type RNA - Early spermatids [nTPM]":"5.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"21.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.4","Single Cell Type RNA - Endothelial cells [nTPM]":"19.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"30.5","Single Cell Type RNA - Erythroid cells [nTPM]":"14.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"32.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"72.4","Single Cell Type RNA - Fibroblasts [nTPM]":"26.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.3","Single Cell Type RNA - granulocytes [nTPM]":"21.0","Single Cell Type RNA - Granulosa cells [nTPM]":"47.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.0","Single Cell Type RNA - Hepatocytes [nTPM]":"25.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"32.1","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.1","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"22.9","Single Cell Type RNA - Langerhans cells [nTPM]":"17.4","Single Cell Type RNA - Late spermatids [nTPM]":"6.8","Single Cell Type RNA - Leydig cells [nTPM]":"21.1","Single Cell Type RNA - Macrophages [nTPM]":"21.8","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"29.3","Single Cell Type RNA - Muller glia cells [nTPM]":"16.0","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"27.6","Single Cell Type RNA - Paneth cells [nTPM]":"25.0","Single Cell Type RNA - Peritubular cells [nTPM]":"21.8","Single Cell Type RNA - Plasma cells [nTPM]":"25.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"35.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"24.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.3","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.2","Single Cell Type RNA - Spermatocytes [nTPM]":"16.1","Single Cell Type RNA - Spermatogonia [nTPM]":"28.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"45.4","Single Cell Type RNA - T-cells [nTPM]":"21.5","Single Cell Type RNA - Theca cells [nTPM]":"41.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"25.6","Single Cell Type RNA - Urothelial cells [nTPM]":"8.2"},{"Gene":"MAN2B1","Gene synonym":["LAMAN","MANB"],"Ensembl":"ENSG00000104774","Gene description":"Mannosidase alpha class 2B member 1","Uniprot":["O00754"],"Chromosome":"19","Position":"12646511-12666742","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Macrophages":"32.8","Plasma cells":"78.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"201.8","intermediate monocyte":"178.8","myeloid DC":"158.8","non-classical monocyte":"138.4","plasmacytoid DC":"187.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"187.5","monocytes":"201.8"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041530","HPA053404"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3200000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA041530":"AB_10795639","HPA053404":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.94e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Tissue RNA - adipose tissue [nTPM]":"35.8","Tissue RNA - adrenal gland [nTPM]":"21.4","Tissue RNA - amygdala [nTPM]":"5.3","Tissue RNA - appendix [nTPM]":"54.6","Tissue RNA - basal ganglia [nTPM]":"6.4","Tissue RNA - bone marrow [nTPM]":"83.6","Tissue RNA - breast [nTPM]":"24.8","Tissue RNA - cerebellum [nTPM]":"6.6","Tissue RNA - cerebral cortex [nTPM]":"5.9","Tissue RNA - cervix [nTPM]":"19.6","Tissue RNA - choroid plexus [nTPM]":"18.5","Tissue RNA - colon [nTPM]":"30.3","Tissue RNA - duodenum [nTPM]":"31.0","Tissue RNA - endometrium 1 [nTPM]":"21.8","Tissue RNA - epididymis [nTPM]":"9.0","Tissue RNA - esophagus [nTPM]":"19.8","Tissue RNA - fallopian tube [nTPM]":"19.9","Tissue RNA - gallbladder [nTPM]":"28.4","Tissue RNA - heart muscle [nTPM]":"16.0","Tissue RNA - hippocampal formation [nTPM]":"4.9","Tissue RNA - hypothalamus [nTPM]":"7.4","Tissue RNA - kidney [nTPM]":"17.3","Tissue RNA - liver [nTPM]":"23.7","Tissue RNA - lung [nTPM]":"46.8","Tissue RNA - lymph node [nTPM]":"52.1","Tissue RNA - medulla oblongata [nTPM]":"10.3","Tissue RNA - midbrain [nTPM]":"6.7","Tissue RNA - ovary [nTPM]":"16.7","Tissue RNA - pancreas [nTPM]":"39.7","Tissue RNA - parathyroid gland [nTPM]":"16.6","Tissue RNA - pituitary gland [nTPM]":"9.9","Tissue RNA - placenta [nTPM]":"24.6","Tissue RNA - pons [nTPM]":"9.5","Tissue RNA - prostate [nTPM]":"20.5","Tissue RNA - rectum [nTPM]":"22.6","Tissue RNA - retina [nTPM]":"1.6","Tissue RNA - salivary gland [nTPM]":"35.2","Tissue RNA - seminal vesicle [nTPM]":"14.9","Tissue RNA - skeletal muscle [nTPM]":"12.1","Tissue RNA - skin 1 [nTPM]":"28.9","Tissue RNA - small intestine [nTPM]":"33.6","Tissue RNA - smooth muscle [nTPM]":"20.2","Tissue RNA - spinal cord [nTPM]":"8.9","Tissue RNA - spleen [nTPM]":"70.1","Tissue RNA - stomach 1 [nTPM]":"32.7","Tissue RNA - testis [nTPM]":"6.4","Tissue RNA - thalamus [nTPM]":"9.7","Tissue RNA - thymus [nTPM]":"23.1","Tissue RNA - thyroid gland [nTPM]":"16.3","Tissue RNA - tongue [nTPM]":"9.4","Tissue RNA - tonsil [nTPM]":"39.3","Tissue RNA - urinary bladder [nTPM]":"35.6","Tissue RNA - vagina [nTPM]":"16.7","Tissue RNA - white matter [nTPM]":"12.4","Cell RNA - A-431 [nTPM]":"52.4","Cell RNA - A549 [nTPM]":"26.3","Cell RNA - AF22 [nTPM]":"26.4","Cell RNA - AN3-CA [nTPM]":"31.3","Cell RNA - ASC diff [nTPM]":"85.8","Cell RNA - ASC TERT1 [nTPM]":"57.3","Cell RNA - BEWO [nTPM]":"74.0","Cell RNA - BJ [nTPM]":"37.9","Cell RNA - BJ hTERT+ [nTPM]":"79.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"33.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"32.4","Cell RNA - CACO-2 [nTPM]":"21.3","Cell RNA - CAPAN-2 [nTPM]":"21.4","Cell RNA - Daudi [nTPM]":"56.9","Cell RNA - EFO-21 [nTPM]":"44.9","Cell RNA - fHDF\/TERT166 [nTPM]":"30.4","Cell RNA - GAMG [nTPM]":"9.4","Cell RNA - HaCaT [nTPM]":"40.1","Cell RNA - HAP1 [nTPM]":"13.6","Cell RNA - HBEC3-KT [nTPM]":"25.6","Cell RNA - HBF TERT88 [nTPM]":"15.7","Cell RNA - HDLM-2 [nTPM]":"28.5","Cell RNA - HEK 293 [nTPM]":"41.6","Cell RNA - HEL [nTPM]":"19.8","Cell RNA - HeLa [nTPM]":"13.6","Cell RNA - Hep G2 [nTPM]":"34.9","Cell RNA - HHSteC [nTPM]":"43.5","Cell RNA - HL-60 [nTPM]":"131.6","Cell RNA - HMC-1 [nTPM]":"130.2","Cell RNA - HSkMC [nTPM]":"68.5","Cell RNA - hTCEpi [nTPM]":"49.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.5","Cell RNA - hTERT-HME1 [nTPM]":"23.3","Cell RNA - hTERT-RPE1 [nTPM]":"35.6","Cell RNA - HUVEC TERT2 [nTPM]":"31.7","Cell RNA - JURKAT [nTPM]":"21.1","Cell RNA - K-562 [nTPM]":"25.6","Cell RNA - Karpas-707 [nTPM]":"41.9","Cell RNA - LHCN-M2 [nTPM]":"17.8","Cell RNA - MCF7 [nTPM]":"40.9","Cell RNA - MOLT-4 [nTPM]":"17.9","Cell RNA - NB-4 [nTPM]":"74.2","Cell RNA - NTERA-2 [nTPM]":"21.9","Cell RNA - OE19 [nTPM]":"26.2","Cell RNA - PC-3 [nTPM]":"32.8","Cell RNA - REH [nTPM]":"40.8","Cell RNA - RH-30 [nTPM]":"36.1","Cell RNA - RPMI-8226 [nTPM]":"28.8","Cell RNA - RPTEC TERT1 [nTPM]":"38.9","Cell RNA - RT4 [nTPM]":"59.8","Cell RNA - SCLC-21H [nTPM]":"8.2","Cell RNA - SH-SY5Y [nTPM]":"25.5","Cell RNA - SiHa [nTPM]":"37.7","Cell RNA - SK-BR-3 [nTPM]":"32.0","Cell RNA - SK-MEL-30 [nTPM]":"63.0","Cell RNA - SuSa [nTPM]":"15.8","Cell RNA - T-47d [nTPM]":"49.4","Cell RNA - THP-1 [nTPM]":"80.0","Cell RNA - TIME [nTPM]":"42.0","Cell RNA - U-138 MG [nTPM]":"44.8","Cell RNA - U-2 OS [nTPM]":"18.4","Cell RNA - U-2197 [nTPM]":"44.0","Cell RNA - U-251 MG [nTPM]":"36.2","Cell RNA - U-266\/70 [nTPM]":"55.4","Cell RNA - U-266\/84 [nTPM]":"65.5","Cell RNA - U-698 [nTPM]":"28.0","Cell RNA - U-87 MG [nTPM]":"30.4","Cell RNA - U-937 [nTPM]":"127.5","Cell RNA - WM-115 [nTPM]":"51.2","Blood RNA - basophil [nTPM]":"12.2","Blood RNA - classical monocyte [nTPM]":"201.8","Blood RNA - eosinophil [nTPM]":"29.7","Blood RNA - gdT-cell [nTPM]":"31.9","Blood RNA - intermediate monocyte [nTPM]":"178.8","Blood RNA - MAIT T-cell [nTPM]":"35.4","Blood RNA - memory B-cell [nTPM]":"32.9","Blood RNA - memory CD4 T-cell [nTPM]":"28.9","Blood RNA - memory CD8 T-cell [nTPM]":"29.0","Blood RNA - myeloid DC [nTPM]":"158.8","Blood RNA - naive B-cell [nTPM]":"26.4","Blood RNA - naive CD4 T-cell [nTPM]":"15.4","Blood RNA - naive CD8 T-cell [nTPM]":"15.9","Blood RNA - neutrophil [nTPM]":"29.4","Blood RNA - NK-cell [nTPM]":"13.2","Blood RNA - non-classical monocyte [nTPM]":"138.4","Blood RNA - plasmacytoid DC [nTPM]":"187.5","Blood RNA - T-reg [nTPM]":"30.7","Blood RNA - total PBMC [nTPM]":"150.3","Brain RNA - amygdala [nTPM]":"5.3","Brain RNA - basal ganglia [nTPM]":"6.4","Brain RNA - cerebellum [nTPM]":"6.6","Brain RNA - cerebral cortex [nTPM]":"5.9","Brain RNA - hippocampal formation [nTPM]":"4.9","Brain RNA - hypothalamus [nTPM]":"7.4","Brain RNA - medulla oblongata [nTPM]":"10.3","Brain RNA - midbrain [nTPM]":"6.7","Brain RNA - pons [nTPM]":"9.5","Brain RNA - spinal cord [nTPM]":"8.9","Brain RNA - thalamus [nTPM]":"9.7","Brain RNA - white matter [nTPM]":"12.4","Single Cell Type RNA - Adipocytes [nTPM]":"1.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.5","Single Cell Type RNA - Astrocytes [nTPM]":"8.5","Single Cell Type RNA - B-cells [nTPM]":"25.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"2.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"2.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - dendritic cells [nTPM]":"20.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.7","Single Cell Type RNA - Early spermatids [nTPM]":"3.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.5","Single Cell Type RNA - Endothelial cells [nTPM]":"3.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"9.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.8","Single Cell Type RNA - Fibroblasts [nTPM]":"7.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.3","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"3.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"15.4","Single Cell Type RNA - Langerhans cells [nTPM]":"24.7","Single Cell Type RNA - Late spermatids [nTPM]":"11.1","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"32.8","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"11.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.5","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"13.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.5","Single Cell Type RNA - Paneth cells [nTPM]":"2.5","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"78.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"1.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.7","Single Cell Type RNA - T-cells [nTPM]":"9.4","Single Cell Type RNA - Theca cells [nTPM]":"2.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.0","Single Cell Type RNA - Urothelial cells [nTPM]":"2.0"},{"Gene":"MANBA","Gene synonym":[],"Ensembl":"ENSG00000109323","Gene description":"Mannosidase beta","Uniprot":["O00462"],"Chromosome":"4","Position":"102630770-102760994","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Macrophages":"74.0","Microglial cells":"111.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"16.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"5.3","granulocytes":"16.6","monocytes":"9.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"15.5","hTCEpi":"13.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053478"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"15000000","Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA053478":"AB_2682165"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.56e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.74e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.1","Tissue RNA - adrenal gland [nTPM]":"12.4","Tissue RNA - amygdala [nTPM]":"1.9","Tissue RNA - appendix [nTPM]":"1.5","Tissue RNA - basal ganglia [nTPM]":"2.4","Tissue RNA - bone marrow [nTPM]":"7.0","Tissue RNA - breast [nTPM]":"6.4","Tissue RNA - cerebellum [nTPM]":"4.7","Tissue RNA - cerebral cortex [nTPM]":"2.2","Tissue RNA - cervix [nTPM]":"6.5","Tissue RNA - choroid plexus [nTPM]":"2.2","Tissue RNA - colon [nTPM]":"6.7","Tissue RNA - duodenum [nTPM]":"1.6","Tissue RNA - endometrium 1 [nTPM]":"6.1","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"3.8","Tissue RNA - fallopian tube [nTPM]":"6.3","Tissue RNA - gallbladder [nTPM]":"1.3","Tissue RNA - heart muscle [nTPM]":"6.6","Tissue RNA - hippocampal formation [nTPM]":"1.1","Tissue RNA - hypothalamus [nTPM]":"2.1","Tissue RNA - kidney [nTPM]":"4.8","Tissue RNA - liver [nTPM]":"4.7","Tissue RNA - lung [nTPM]":"10.5","Tissue RNA - lymph node [nTPM]":"2.1","Tissue RNA - medulla oblongata [nTPM]":"3.8","Tissue RNA - midbrain [nTPM]":"2.9","Tissue RNA - ovary [nTPM]":"8.8","Tissue RNA - pancreas [nTPM]":"8.3","Tissue RNA - parathyroid gland [nTPM]":"3.0","Tissue RNA - pituitary gland [nTPM]":"5.0","Tissue RNA - placenta [nTPM]":"3.7","Tissue RNA - pons [nTPM]":"4.7","Tissue RNA - prostate [nTPM]":"4.3","Tissue RNA - rectum [nTPM]":"1.1","Tissue RNA - retina [nTPM]":"2.7","Tissue RNA - salivary gland [nTPM]":"8.9","Tissue RNA - seminal vesicle [nTPM]":"2.0","Tissue RNA - skeletal muscle [nTPM]":"3.0","Tissue RNA - skin 1 [nTPM]":"4.5","Tissue RNA - small intestine [nTPM]":"8.5","Tissue RNA - smooth muscle [nTPM]":"2.4","Tissue RNA - spinal cord [nTPM]":"3.0","Tissue RNA - spleen [nTPM]":"12.0","Tissue RNA - stomach 1 [nTPM]":"9.1","Tissue RNA - testis [nTPM]":"1.6","Tissue RNA - thalamus [nTPM]":"3.5","Tissue RNA - thymus [nTPM]":"1.2","Tissue RNA - thyroid gland [nTPM]":"7.1","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"2.0","Tissue RNA - urinary bladder [nTPM]":"8.1","Tissue RNA - vagina [nTPM]":"5.8","Tissue RNA - white matter [nTPM]":"3.7","Cell RNA - A-431 [nTPM]":"2.9","Cell RNA - A549 [nTPM]":"1.4","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"1.6","Cell RNA - ASC diff [nTPM]":"15.5","Cell RNA - ASC TERT1 [nTPM]":"12.1","Cell RNA - BEWO [nTPM]":"0.9","Cell RNA - BJ [nTPM]":"1.1","Cell RNA - BJ hTERT+ [nTPM]":"6.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.1","Cell RNA - CACO-2 [nTPM]":"1.7","Cell RNA - CAPAN-2 [nTPM]":"1.0","Cell RNA - Daudi [nTPM]":"3.6","Cell RNA - EFO-21 [nTPM]":"1.4","Cell RNA - fHDF\/TERT166 [nTPM]":"2.7","Cell RNA - GAMG [nTPM]":"3.9","Cell RNA - HaCaT [nTPM]":"1.0","Cell RNA - HAP1 [nTPM]":"3.0","Cell RNA - HBEC3-KT [nTPM]":"2.2","Cell RNA - HBF TERT88 [nTPM]":"1.1","Cell RNA - HDLM-2 [nTPM]":"2.2","Cell RNA - HEK 293 [nTPM]":"0.7","Cell RNA - HEL [nTPM]":"3.0","Cell RNA - HeLa [nTPM]":"1.1","Cell RNA - Hep G2 [nTPM]":"0.7","Cell RNA - HHSteC [nTPM]":"2.7","Cell RNA - HL-60 [nTPM]":"2.8","Cell RNA - HMC-1 [nTPM]":"8.2","Cell RNA - HSkMC [nTPM]":"3.7","Cell RNA - hTCEpi [nTPM]":"13.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.6","Cell RNA - hTERT-HME1 [nTPM]":"3.4","Cell RNA - hTERT-RPE1 [nTPM]":"8.9","Cell RNA - HUVEC TERT2 [nTPM]":"3.0","Cell RNA - JURKAT [nTPM]":"1.2","Cell RNA - K-562 [nTPM]":"3.6","Cell RNA - Karpas-707 [nTPM]":"2.0","Cell RNA - LHCN-M2 [nTPM]":"3.4","Cell RNA - MCF7 [nTPM]":"1.4","Cell RNA - MOLT-4 [nTPM]":"2.0","Cell RNA - NB-4 [nTPM]":"2.3","Cell RNA - NTERA-2 [nTPM]":"1.3","Cell RNA - OE19 [nTPM]":"1.9","Cell RNA - PC-3 [nTPM]":"1.1","Cell RNA - REH [nTPM]":"1.9","Cell RNA - RH-30 [nTPM]":"1.6","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"3.4","Cell RNA - RT4 [nTPM]":"2.3","Cell RNA - SCLC-21H [nTPM]":"1.4","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"1.4","Cell RNA - SK-BR-3 [nTPM]":"1.9","Cell RNA - SK-MEL-30 [nTPM]":"1.5","Cell RNA - SuSa [nTPM]":"5.4","Cell RNA - T-47d [nTPM]":"4.5","Cell RNA - THP-1 [nTPM]":"1.8","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"2.0","Cell RNA - U-2 OS [nTPM]":"1.3","Cell RNA - U-2197 [nTPM]":"9.3","Cell RNA - U-251 MG [nTPM]":"1.2","Cell RNA - U-266\/70 [nTPM]":"1.3","Cell RNA - U-266\/84 [nTPM]":"5.8","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"3.1","Cell RNA - U-937 [nTPM]":"1.5","Cell RNA - WM-115 [nTPM]":"1.6","Blood RNA - basophil [nTPM]":"4.0","Blood RNA - classical monocyte [nTPM]":"6.8","Blood RNA - eosinophil [nTPM]":"16.6","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"6.1","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"1.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"5.3","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"6.1","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"9.1","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"0.5","Blood RNA - total PBMC [nTPM]":"3.1","Brain RNA - amygdala [nTPM]":"1.9","Brain RNA - basal ganglia [nTPM]":"2.4","Brain RNA - cerebellum [nTPM]":"4.7","Brain RNA - cerebral cortex [nTPM]":"2.2","Brain RNA - hippocampal formation [nTPM]":"1.1","Brain RNA - hypothalamus [nTPM]":"2.1","Brain RNA - medulla oblongata [nTPM]":"3.8","Brain RNA - midbrain [nTPM]":"2.9","Brain RNA - pons [nTPM]":"4.7","Brain RNA - spinal cord [nTPM]":"3.0","Brain RNA - thalamus [nTPM]":"3.5","Brain RNA - white matter [nTPM]":"3.7","Single Cell Type RNA - Adipocytes [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"35.6","Single Cell Type RNA - Astrocytes [nTPM]":"24.5","Single Cell Type RNA - B-cells [nTPM]":"45.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.0","Single Cell Type RNA - Bipolar cells [nTPM]":"6.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"13.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"42.3","Single Cell Type RNA - dendritic cells [nTPM]":"14.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.1","Single Cell Type RNA - Early spermatids [nTPM]":"2.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.9","Single Cell Type RNA - Endothelial cells [nTPM]":"8.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"19.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"36.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.3","Single Cell Type RNA - Fibroblasts [nTPM]":"13.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"25.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.8","Single Cell Type RNA - granulocytes [nTPM]":"34.8","Single Cell Type RNA - Granulosa cells [nTPM]":"5.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.4","Single Cell Type RNA - Hepatocytes [nTPM]":"17.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"43.6","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"66.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.5","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"58.5","Single Cell Type RNA - Langerhans cells [nTPM]":"29.6","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"9.0","Single Cell Type RNA - Macrophages [nTPM]":"74.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"111.5","Single Cell Type RNA - monocytes [nTPM]":"52.8","Single Cell Type RNA - Muller glia cells [nTPM]":"5.2","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"31.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"66.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.5","Single Cell Type RNA - Paneth cells [nTPM]":"17.3","Single Cell Type RNA - Peritubular cells [nTPM]":"19.9","Single Cell Type RNA - Plasma cells [nTPM]":"17.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"1.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.6","Single Cell Type RNA - T-cells [nTPM]":"16.9","Single Cell Type RNA - Theca cells [nTPM]":"12.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.2","Single Cell Type RNA - Urothelial cells [nTPM]":"9.7"},{"Gene":"MAP2K3","Gene synonym":["MAPKK3","MEK3","MKK3","PRKMK3"],"Ensembl":"ENSG00000034152","Gene description":"Mitogen-activated protein kinase kinase 3","Uniprot":["P46734"],"Chromosome":"17","Position":"21284672-21315232","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"212.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"325.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB018548"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"28000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB018548":"AB_631927"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Tissue RNA - adipose tissue [nTPM]":"47.3","Tissue RNA - adrenal gland [nTPM]":"32.5","Tissue RNA - amygdala [nTPM]":"12.9","Tissue RNA - appendix [nTPM]":"35.3","Tissue RNA - basal ganglia [nTPM]":"12.1","Tissue RNA - bone marrow [nTPM]":"212.4","Tissue RNA - breast [nTPM]":"30.7","Tissue RNA - cerebellum [nTPM]":"17.6","Tissue RNA - cerebral cortex [nTPM]":"23.2","Tissue RNA - cervix [nTPM]":"22.7","Tissue RNA - choroid plexus [nTPM]":"22.6","Tissue RNA - colon [nTPM]":"33.1","Tissue RNA - duodenum [nTPM]":"49.0","Tissue RNA - endometrium 1 [nTPM]":"17.1","Tissue RNA - epididymis [nTPM]":"14.5","Tissue RNA - esophagus [nTPM]":"62.7","Tissue RNA - fallopian tube [nTPM]":"29.9","Tissue RNA - gallbladder [nTPM]":"40.0","Tissue RNA - heart muscle [nTPM]":"66.7","Tissue RNA - hippocampal formation [nTPM]":"11.5","Tissue RNA - hypothalamus [nTPM]":"14.4","Tissue RNA - kidney [nTPM]":"45.7","Tissue RNA - liver [nTPM]":"95.7","Tissue RNA - lung [nTPM]":"67.5","Tissue RNA - lymph node [nTPM]":"34.0","Tissue RNA - medulla oblongata [nTPM]":"13.6","Tissue RNA - midbrain [nTPM]":"14.3","Tissue RNA - ovary [nTPM]":"12.6","Tissue RNA - pancreas [nTPM]":"33.6","Tissue RNA - parathyroid gland [nTPM]":"17.9","Tissue RNA - pituitary gland [nTPM]":"37.1","Tissue RNA - placenta [nTPM]":"28.9","Tissue RNA - pons [nTPM]":"14.2","Tissue RNA - prostate [nTPM]":"28.9","Tissue RNA - rectum [nTPM]":"24.1","Tissue RNA - retina [nTPM]":"6.0","Tissue RNA - salivary gland [nTPM]":"45.3","Tissue RNA - seminal vesicle [nTPM]":"16.5","Tissue RNA - skeletal muscle [nTPM]":"132.7","Tissue RNA - skin 1 [nTPM]":"53.1","Tissue RNA - small intestine [nTPM]":"41.0","Tissue RNA - smooth muscle [nTPM]":"22.5","Tissue RNA - spinal cord [nTPM]":"14.3","Tissue RNA - spleen [nTPM]":"60.4","Tissue RNA - stomach 1 [nTPM]":"42.8","Tissue RNA - testis [nTPM]":"6.2","Tissue RNA - thalamus [nTPM]":"15.8","Tissue RNA - thymus [nTPM]":"20.9","Tissue RNA - thyroid gland [nTPM]":"24.0","Tissue RNA - tongue [nTPM]":"74.6","Tissue RNA - tonsil [nTPM]":"41.1","Tissue RNA - urinary bladder [nTPM]":"54.1","Tissue RNA - vagina [nTPM]":"33.4","Tissue RNA - white matter [nTPM]":"17.0","Cell RNA - A-431 [nTPM]":"75.5","Cell RNA - A549 [nTPM]":"73.9","Cell RNA - AF22 [nTPM]":"9.7","Cell RNA - AN3-CA [nTPM]":"44.5","Cell RNA - ASC diff [nTPM]":"57.7","Cell RNA - ASC TERT1 [nTPM]":"36.6","Cell RNA - BEWO [nTPM]":"36.3","Cell RNA - BJ [nTPM]":"113.0","Cell RNA - BJ hTERT+ [nTPM]":"121.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"88.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"80.5","Cell RNA - CACO-2 [nTPM]":"82.9","Cell RNA - CAPAN-2 [nTPM]":"46.6","Cell RNA - Daudi [nTPM]":"68.1","Cell RNA - EFO-21 [nTPM]":"44.7","Cell RNA - fHDF\/TERT166 [nTPM]":"178.3","Cell RNA - GAMG [nTPM]":"74.2","Cell RNA - HaCaT [nTPM]":"72.4","Cell RNA - HAP1 [nTPM]":"31.0","Cell RNA - HBEC3-KT [nTPM]":"100.5","Cell RNA - HBF TERT88 [nTPM]":"62.1","Cell RNA - HDLM-2 [nTPM]":"69.5","Cell RNA - HEK 293 [nTPM]":"56.9","Cell RNA - HEL [nTPM]":"39.2","Cell RNA - HeLa [nTPM]":"42.0","Cell RNA - Hep G2 [nTPM]":"76.1","Cell RNA - HHSteC [nTPM]":"18.2","Cell RNA - HL-60 [nTPM]":"51.9","Cell RNA - HMC-1 [nTPM]":"76.7","Cell RNA - HSkMC [nTPM]":"28.5","Cell RNA - hTCEpi [nTPM]":"28.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"120.6","Cell RNA - hTERT-HME1 [nTPM]":"35.9","Cell RNA - hTERT-RPE1 [nTPM]":"27.7","Cell RNA - HUVEC TERT2 [nTPM]":"40.0","Cell RNA - JURKAT [nTPM]":"38.6","Cell RNA - K-562 [nTPM]":"7.7","Cell RNA - Karpas-707 [nTPM]":"33.2","Cell RNA - LHCN-M2 [nTPM]":"74.7","Cell RNA - MCF7 [nTPM]":"74.1","Cell RNA - MOLT-4 [nTPM]":"25.5","Cell RNA - NB-4 [nTPM]":"49.3","Cell RNA - NTERA-2 [nTPM]":"28.1","Cell RNA - OE19 [nTPM]":"134.1","Cell RNA - PC-3 [nTPM]":"42.3","Cell RNA - REH [nTPM]":"53.0","Cell RNA - RH-30 [nTPM]":"62.2","Cell RNA - RPMI-8226 [nTPM]":"50.0","Cell RNA - RPTEC TERT1 [nTPM]":"50.5","Cell RNA - RT4 [nTPM]":"77.4","Cell RNA - SCLC-21H [nTPM]":"26.3","Cell RNA - SH-SY5Y [nTPM]":"9.4","Cell RNA - SiHa [nTPM]":"41.7","Cell RNA - SK-BR-3 [nTPM]":"45.9","Cell RNA - SK-MEL-30 [nTPM]":"82.0","Cell RNA - SuSa [nTPM]":"95.7","Cell RNA - T-47d [nTPM]":"22.5","Cell RNA - THP-1 [nTPM]":"17.7","Cell RNA - TIME [nTPM]":"36.8","Cell RNA - U-138 MG [nTPM]":"83.0","Cell RNA - U-2 OS [nTPM]":"68.4","Cell RNA - U-2197 [nTPM]":"90.1","Cell RNA - U-251 MG [nTPM]":"73.9","Cell RNA - U-266\/70 [nTPM]":"39.8","Cell RNA - U-266\/84 [nTPM]":"21.8","Cell RNA - U-698 [nTPM]":"88.1","Cell RNA - U-87 MG [nTPM]":"80.2","Cell RNA - U-937 [nTPM]":"44.3","Cell RNA - WM-115 [nTPM]":"44.1","Blood RNA - basophil [nTPM]":"54.1","Blood RNA - classical monocyte [nTPM]":"49.3","Blood RNA - eosinophil [nTPM]":"77.8","Blood RNA - gdT-cell [nTPM]":"35.9","Blood RNA - intermediate monocyte [nTPM]":"72.1","Blood RNA - MAIT T-cell [nTPM]":"31.1","Blood RNA - memory B-cell [nTPM]":"33.3","Blood RNA - memory CD4 T-cell [nTPM]":"29.1","Blood RNA - memory CD8 T-cell [nTPM]":"33.6","Blood RNA - myeloid DC [nTPM]":"49.6","Blood RNA - naive B-cell [nTPM]":"25.5","Blood RNA - naive CD4 T-cell [nTPM]":"17.9","Blood RNA - naive CD8 T-cell [nTPM]":"24.1","Blood RNA - neutrophil [nTPM]":"145.6","Blood RNA - NK-cell [nTPM]":"15.3","Blood RNA - non-classical monocyte [nTPM]":"104.7","Blood RNA - plasmacytoid DC [nTPM]":"35.4","Blood RNA - T-reg [nTPM]":"44.5","Blood RNA - total PBMC [nTPM]":"35.6","Brain RNA - amygdala [nTPM]":"12.9","Brain RNA - basal ganglia [nTPM]":"12.1","Brain RNA - cerebellum [nTPM]":"17.6","Brain RNA - cerebral cortex [nTPM]":"23.2","Brain RNA - hippocampal formation [nTPM]":"11.5","Brain RNA - hypothalamus [nTPM]":"14.4","Brain RNA - medulla oblongata [nTPM]":"13.6","Brain RNA - midbrain [nTPM]":"14.3","Brain RNA - pons [nTPM]":"14.2","Brain RNA - spinal cord [nTPM]":"14.3","Brain RNA - thalamus [nTPM]":"15.8","Brain RNA - white matter [nTPM]":"17.0","Single Cell Type RNA - Adipocytes [nTPM]":"44.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"53.6","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"51.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"258.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"188.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"57.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"97.9","Single Cell Type RNA - Bipolar cells [nTPM]":"7.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"69.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"51.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"21.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"44.3","Single Cell Type RNA - Club cells [nTPM]":"50.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"73.3","Single Cell Type RNA - dendritic cells [nTPM]":"117.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"109.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"74.3","Single Cell Type RNA - Ductal cells [nTPM]":"99.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"130.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"44.8","Single Cell Type RNA - Endothelial cells [nTPM]":"49.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"120.4","Single Cell Type RNA - Erythroid cells [nTPM]":"325.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"79.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"82.0","Single Cell Type RNA - Fibroblasts [nTPM]":"43.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"68.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"237.8","Single Cell Type RNA - granulocytes [nTPM]":"94.0","Single Cell Type RNA - Granulosa cells [nTPM]":"11.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.1","Single Cell Type RNA - Hepatocytes [nTPM]":"73.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"49.0","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"77.0","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"59.4","Single Cell Type RNA - Langerhans cells [nTPM]":"278.7","Single Cell Type RNA - Late spermatids [nTPM]":"1.8","Single Cell Type RNA - Leydig cells [nTPM]":"12.2","Single Cell Type RNA - Macrophages [nTPM]":"118.1","Single Cell Type RNA - Melanocytes [nTPM]":"87.2","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"48.3","Single Cell Type RNA - Muller glia cells [nTPM]":"17.3","Single Cell Type RNA - NK-cells [nTPM]":"35.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"129.1","Single Cell Type RNA - Paneth cells [nTPM]":"135.3","Single Cell Type RNA - Peritubular cells [nTPM]":"16.6","Single Cell Type RNA - Plasma cells [nTPM]":"85.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"158.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"60.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"44.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"40.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"61.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"42.4","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"5.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"97.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"218.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"67.0","Single Cell Type RNA - T-cells [nTPM]":"62.6","Single Cell Type RNA - Theca cells [nTPM]":"10.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"58.5","Single Cell Type RNA - Urothelial cells [nTPM]":"255.7"},{"Gene":"MAP3K20","Gene synonym":["MLK7","MLTK","MLTKalpha","MLTKbeta","MRK","ZAK"],"Ensembl":"ENSG00000091436","Gene description":"Mitogen-activated protein kinase kinase kinase 20","Uniprot":["Q9NYL2"],"Chromosome":"2","Position":"173075435-173268015","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"261.9","tongue":"279.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"57.5","Alveolar cells type 2":"57.7","Cytotrophoblasts":"52.6","Endometrial stromal cells":"96.7","Granulosa cells":"100.7","Smooth muscle cells":"83.2","Theca cells":"70.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"15.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"15.5","monocytes":"9.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-138 MG":"176.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017205"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA017205":"AB_1858933"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.99e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.41e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Tissue RNA - adipose tissue [nTPM]":"71.0","Tissue RNA - adrenal gland [nTPM]":"11.4","Tissue RNA - amygdala [nTPM]":"9.5","Tissue RNA - appendix [nTPM]":"20.5","Tissue RNA - basal ganglia [nTPM]":"9.7","Tissue RNA - bone marrow [nTPM]":"4.7","Tissue RNA - breast [nTPM]":"21.4","Tissue RNA - cerebellum [nTPM]":"10.3","Tissue RNA - cerebral cortex [nTPM]":"8.5","Tissue RNA - cervix [nTPM]":"44.9","Tissue RNA - choroid plexus [nTPM]":"15.7","Tissue RNA - colon [nTPM]":"65.8","Tissue RNA - duodenum [nTPM]":"13.0","Tissue RNA - endometrium 1 [nTPM]":"76.4","Tissue RNA - epididymis [nTPM]":"18.6","Tissue RNA - esophagus [nTPM]":"50.0","Tissue RNA - fallopian tube [nTPM]":"48.0","Tissue RNA - gallbladder [nTPM]":"31.4","Tissue RNA - heart muscle [nTPM]":"195.7","Tissue RNA - hippocampal formation [nTPM]":"9.3","Tissue RNA - hypothalamus [nTPM]":"12.1","Tissue RNA - kidney [nTPM]":"7.5","Tissue RNA - liver [nTPM]":"25.2","Tissue RNA - lung [nTPM]":"22.5","Tissue RNA - lymph node [nTPM]":"9.8","Tissue RNA - medulla oblongata [nTPM]":"13.8","Tissue RNA - midbrain [nTPM]":"14.7","Tissue RNA - ovary [nTPM]":"69.5","Tissue RNA - pancreas [nTPM]":"11.7","Tissue RNA - parathyroid gland [nTPM]":"49.3","Tissue RNA - pituitary gland [nTPM]":"3.8","Tissue RNA - placenta [nTPM]":"27.6","Tissue RNA - pons [nTPM]":"11.2","Tissue RNA - prostate [nTPM]":"44.0","Tissue RNA - rectum [nTPM]":"20.9","Tissue RNA - retina [nTPM]":"2.5","Tissue RNA - salivary gland [nTPM]":"12.4","Tissue RNA - seminal vesicle [nTPM]":"57.1","Tissue RNA - skeletal muscle [nTPM]":"261.9","Tissue RNA - skin 1 [nTPM]":"14.1","Tissue RNA - small intestine [nTPM]":"19.2","Tissue RNA - smooth muscle [nTPM]":"75.0","Tissue RNA - spinal cord [nTPM]":"11.1","Tissue RNA - spleen [nTPM]":"12.5","Tissue RNA - stomach 1 [nTPM]":"31.5","Tissue RNA - testis [nTPM]":"10.6","Tissue RNA - thalamus [nTPM]":"12.5","Tissue RNA - thymus [nTPM]":"11.5","Tissue RNA - thyroid gland [nTPM]":"16.4","Tissue RNA - tongue [nTPM]":"279.7","Tissue RNA - tonsil [nTPM]":"10.2","Tissue RNA - urinary bladder [nTPM]":"56.1","Tissue RNA - vagina [nTPM]":"21.2","Tissue RNA - white matter [nTPM]":"9.4","Cell RNA - A-431 [nTPM]":"34.6","Cell RNA - A549 [nTPM]":"28.6","Cell RNA - AF22 [nTPM]":"22.0","Cell RNA - AN3-CA [nTPM]":"29.1","Cell RNA - ASC diff [nTPM]":"62.7","Cell RNA - ASC TERT1 [nTPM]":"92.5","Cell RNA - BEWO [nTPM]":"13.8","Cell RNA - BJ [nTPM]":"121.9","Cell RNA - BJ hTERT+ [nTPM]":"94.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"55.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"59.6","Cell RNA - CACO-2 [nTPM]":"19.5","Cell RNA - CAPAN-2 [nTPM]":"22.2","Cell RNA - Daudi [nTPM]":"26.5","Cell RNA - EFO-21 [nTPM]":"31.2","Cell RNA - fHDF\/TERT166 [nTPM]":"122.5","Cell RNA - GAMG [nTPM]":"48.8","Cell RNA - HaCaT [nTPM]":"22.9","Cell RNA - HAP1 [nTPM]":"33.1","Cell RNA - HBEC3-KT [nTPM]":"64.6","Cell RNA - HBF TERT88 [nTPM]":"124.2","Cell RNA - HDLM-2 [nTPM]":"52.0","Cell RNA - HEK 293 [nTPM]":"22.0","Cell RNA - HEL [nTPM]":"43.3","Cell RNA - HeLa [nTPM]":"30.5","Cell RNA - Hep G2 [nTPM]":"4.1","Cell RNA - HHSteC [nTPM]":"24.8","Cell RNA - HL-60 [nTPM]":"39.3","Cell RNA - HMC-1 [nTPM]":"43.8","Cell RNA - HSkMC [nTPM]":"74.7","Cell RNA - hTCEpi [nTPM]":"27.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"105.2","Cell RNA - hTERT-HME1 [nTPM]":"164.2","Cell RNA - hTERT-RPE1 [nTPM]":"46.3","Cell RNA - HUVEC TERT2 [nTPM]":"37.5","Cell RNA - JURKAT [nTPM]":"28.5","Cell RNA - K-562 [nTPM]":"19.8","Cell RNA - Karpas-707 [nTPM]":"4.9","Cell RNA - LHCN-M2 [nTPM]":"36.8","Cell RNA - MCF7 [nTPM]":"14.8","Cell RNA - MOLT-4 [nTPM]":"24.8","Cell RNA - NB-4 [nTPM]":"19.0","Cell RNA - NTERA-2 [nTPM]":"12.2","Cell RNA - OE19 [nTPM]":"28.9","Cell RNA - PC-3 [nTPM]":"16.0","Cell RNA - REH [nTPM]":"36.2","Cell RNA - RH-30 [nTPM]":"45.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"13.6","Cell RNA - RT4 [nTPM]":"19.6","Cell RNA - SCLC-21H [nTPM]":"12.9","Cell RNA - SH-SY5Y [nTPM]":"12.4","Cell RNA - SiHa [nTPM]":"47.0","Cell RNA - SK-BR-3 [nTPM]":"11.3","Cell RNA - SK-MEL-30 [nTPM]":"19.7","Cell RNA - SuSa [nTPM]":"35.6","Cell RNA - T-47d [nTPM]":"12.9","Cell RNA - THP-1 [nTPM]":"20.9","Cell RNA - TIME [nTPM]":"37.9","Cell RNA - U-138 MG [nTPM]":"176.3","Cell RNA - U-2 OS [nTPM]":"71.4","Cell RNA - U-2197 [nTPM]":"53.1","Cell RNA - U-251 MG [nTPM]":"27.9","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"5.5","Cell RNA - U-87 MG [nTPM]":"126.2","Cell RNA - U-937 [nTPM]":"10.6","Cell RNA - WM-115 [nTPM]":"18.9","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"9.4","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"8.3","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"1.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"15.5","Blood RNA - naive B-cell [nTPM]":"2.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.8","Blood RNA - neutrophil [nTPM]":"2.6","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"8.2","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"3.4","Brain RNA - amygdala [nTPM]":"9.5","Brain RNA - basal ganglia [nTPM]":"9.7","Brain RNA - cerebellum [nTPM]":"10.3","Brain RNA - cerebral cortex [nTPM]":"8.5","Brain RNA - hippocampal formation [nTPM]":"9.3","Brain RNA - hypothalamus [nTPM]":"12.1","Brain RNA - medulla oblongata [nTPM]":"13.8","Brain RNA - midbrain [nTPM]":"14.7","Brain RNA - pons [nTPM]":"11.2","Brain RNA - spinal cord [nTPM]":"11.1","Brain RNA - thalamus [nTPM]":"12.5","Brain RNA - white matter [nTPM]":"9.4","Single Cell Type RNA - Adipocytes [nTPM]":"57.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"57.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"20.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"44.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"7.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"52.6","Single Cell Type RNA - dendritic cells [nTPM]":"2.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"43.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"36.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"96.7","Single Cell Type RNA - Endothelial cells [nTPM]":"14.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"27.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.9","Single Cell Type RNA - Fibroblasts [nTPM]":"36.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"35.6","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"100.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"15.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"15.5","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"38.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"83.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"21.6","Single Cell Type RNA - T-cells [nTPM]":"3.6","Single Cell Type RNA - Theca cells [nTPM]":"70.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"MAP3K7","Gene synonym":["MEKK7","TAK1"],"Ensembl":"ENSG00000135341","Gene description":"Mitogen-activated protein kinase kinase kinase 7","Uniprot":["O43318"],"Chromosome":"6","Position":"90513573-90587072","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Host-virus interaction","Stress response","Transcription","Transcription regulation"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"137.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007633","HPA075335"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nuclear speckles","Plasma membrane"],"Antibody RRID":{"HPA007633":"AB_1079359","HPA075335":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.51e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Tissue RNA - adipose tissue [nTPM]":"11.8","Tissue RNA - adrenal gland [nTPM]":"12.5","Tissue RNA - amygdala [nTPM]":"13.1","Tissue RNA - appendix [nTPM]":"12.5","Tissue RNA - basal ganglia [nTPM]":"15.1","Tissue RNA - bone marrow [nTPM]":"8.7","Tissue RNA - breast [nTPM]":"14.3","Tissue RNA - cerebellum [nTPM]":"15.6","Tissue RNA - cerebral cortex [nTPM]":"17.3","Tissue RNA - cervix [nTPM]":"14.3","Tissue RNA - choroid plexus [nTPM]":"11.7","Tissue RNA - colon [nTPM]":"11.6","Tissue RNA - duodenum [nTPM]":"9.2","Tissue RNA - endometrium 1 [nTPM]":"16.6","Tissue RNA - epididymis [nTPM]":"16.5","Tissue RNA - esophagus [nTPM]":"10.6","Tissue RNA - fallopian tube [nTPM]":"11.0","Tissue RNA - gallbladder [nTPM]":"12.7","Tissue RNA - heart muscle [nTPM]":"16.9","Tissue RNA - hippocampal formation [nTPM]":"14.7","Tissue RNA - hypothalamus [nTPM]":"14.9","Tissue RNA - kidney [nTPM]":"11.4","Tissue RNA - liver [nTPM]":"11.6","Tissue RNA - lung [nTPM]":"10.4","Tissue RNA - lymph node [nTPM]":"16.4","Tissue RNA - medulla oblongata [nTPM]":"15.3","Tissue RNA - midbrain [nTPM]":"13.7","Tissue RNA - ovary [nTPM]":"15.8","Tissue RNA - pancreas [nTPM]":"9.7","Tissue RNA - parathyroid gland [nTPM]":"16.3","Tissue RNA - pituitary gland [nTPM]":"13.0","Tissue RNA - placenta [nTPM]":"17.4","Tissue RNA - pons [nTPM]":"15.8","Tissue RNA - prostate [nTPM]":"14.9","Tissue RNA - rectum [nTPM]":"10.9","Tissue RNA - retina [nTPM]":"23.5","Tissue RNA - salivary gland [nTPM]":"12.1","Tissue RNA - seminal vesicle [nTPM]":"13.3","Tissue RNA - skeletal muscle [nTPM]":"16.9","Tissue RNA - skin 1 [nTPM]":"13.9","Tissue RNA - small intestine [nTPM]":"9.8","Tissue RNA - smooth muscle [nTPM]":"14.0","Tissue RNA - spinal cord [nTPM]":"15.3","Tissue RNA - spleen [nTPM]":"17.6","Tissue RNA - stomach 1 [nTPM]":"10.8","Tissue RNA - testis [nTPM]":"9.9","Tissue RNA - thalamus [nTPM]":"13.8","Tissue RNA - thymus [nTPM]":"20.8","Tissue RNA - thyroid gland [nTPM]":"14.7","Tissue RNA - tongue [nTPM]":"18.4","Tissue RNA - tonsil [nTPM]":"16.8","Tissue RNA - urinary bladder [nTPM]":"14.3","Tissue RNA - vagina [nTPM]":"12.2","Tissue RNA - white matter [nTPM]":"22.4","Cell RNA - A-431 [nTPM]":"16.7","Cell RNA - A549 [nTPM]":"14.4","Cell RNA - AF22 [nTPM]":"41.3","Cell RNA - AN3-CA [nTPM]":"35.6","Cell RNA - ASC diff [nTPM]":"29.5","Cell RNA - ASC TERT1 [nTPM]":"39.1","Cell RNA - BEWO [nTPM]":"29.0","Cell RNA - BJ [nTPM]":"32.7","Cell RNA - BJ hTERT+ [nTPM]":"37.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"28.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"36.1","Cell RNA - CACO-2 [nTPM]":"18.6","Cell RNA - CAPAN-2 [nTPM]":"15.5","Cell RNA - Daudi [nTPM]":"36.9","Cell RNA - EFO-21 [nTPM]":"20.4","Cell RNA - fHDF\/TERT166 [nTPM]":"35.6","Cell RNA - GAMG [nTPM]":"25.6","Cell RNA - HaCaT [nTPM]":"17.3","Cell RNA - HAP1 [nTPM]":"26.3","Cell RNA - HBEC3-KT [nTPM]":"25.5","Cell RNA - HBF TERT88 [nTPM]":"48.7","Cell RNA - HDLM-2 [nTPM]":"19.0","Cell RNA - HEK 293 [nTPM]":"27.7","Cell RNA - HEL [nTPM]":"32.9","Cell RNA - HeLa [nTPM]":"19.9","Cell RNA - Hep G2 [nTPM]":"24.9","Cell RNA - HHSteC [nTPM]":"30.8","Cell RNA - HL-60 [nTPM]":"36.9","Cell RNA - HMC-1 [nTPM]":"24.4","Cell RNA - HSkMC [nTPM]":"32.5","Cell RNA - hTCEpi [nTPM]":"30.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"28.2","Cell RNA - hTERT-HME1 [nTPM]":"34.2","Cell RNA - hTERT-RPE1 [nTPM]":"33.1","Cell RNA - HUVEC TERT2 [nTPM]":"27.4","Cell RNA - JURKAT [nTPM]":"31.8","Cell RNA - K-562 [nTPM]":"67.0","Cell RNA - Karpas-707 [nTPM]":"29.3","Cell RNA - LHCN-M2 [nTPM]":"41.8","Cell RNA - MCF7 [nTPM]":"20.3","Cell RNA - MOLT-4 [nTPM]":"17.2","Cell RNA - NB-4 [nTPM]":"31.2","Cell RNA - NTERA-2 [nTPM]":"34.0","Cell RNA - OE19 [nTPM]":"25.7","Cell RNA - PC-3 [nTPM]":"18.0","Cell RNA - REH [nTPM]":"29.3","Cell RNA - RH-30 [nTPM]":"73.9","Cell RNA - RPMI-8226 [nTPM]":"18.0","Cell RNA - RPTEC TERT1 [nTPM]":"24.2","Cell RNA - RT4 [nTPM]":"18.4","Cell RNA - SCLC-21H [nTPM]":"20.8","Cell RNA - SH-SY5Y [nTPM]":"29.5","Cell RNA - SiHa [nTPM]":"22.9","Cell RNA - SK-BR-3 [nTPM]":"15.6","Cell RNA - SK-MEL-30 [nTPM]":"24.8","Cell RNA - SuSa [nTPM]":"32.2","Cell RNA - T-47d [nTPM]":"15.5","Cell RNA - THP-1 [nTPM]":"64.7","Cell RNA - TIME [nTPM]":"26.5","Cell RNA - U-138 MG [nTPM]":"23.3","Cell RNA - U-2 OS [nTPM]":"14.7","Cell RNA - U-2197 [nTPM]":"21.6","Cell RNA - U-251 MG [nTPM]":"30.9","Cell RNA - U-266\/70 [nTPM]":"25.9","Cell RNA - U-266\/84 [nTPM]":"24.7","Cell RNA - U-698 [nTPM]":"15.8","Cell RNA - U-87 MG [nTPM]":"35.7","Cell RNA - U-937 [nTPM]":"39.7","Cell RNA - WM-115 [nTPM]":"35.0","Blood RNA - basophil [nTPM]":"18.2","Blood RNA - classical monocyte [nTPM]":"11.5","Blood RNA - eosinophil [nTPM]":"18.4","Blood RNA - gdT-cell [nTPM]":"12.8","Blood RNA - intermediate monocyte [nTPM]":"15.9","Blood RNA - MAIT T-cell [nTPM]":"14.5","Blood RNA - memory B-cell [nTPM]":"13.0","Blood RNA - memory CD4 T-cell [nTPM]":"12.3","Blood RNA - memory CD8 T-cell [nTPM]":"12.5","Blood RNA - myeloid DC [nTPM]":"14.6","Blood RNA - naive B-cell [nTPM]":"9.9","Blood RNA - naive CD4 T-cell [nTPM]":"13.7","Blood RNA - naive CD8 T-cell [nTPM]":"13.4","Blood RNA - neutrophil [nTPM]":"11.5","Blood RNA - NK-cell [nTPM]":"17.9","Blood RNA - non-classical monocyte [nTPM]":"17.6","Blood RNA - plasmacytoid DC [nTPM]":"8.9","Blood RNA - T-reg [nTPM]":"20.8","Blood RNA - total PBMC [nTPM]":"13.4","Brain RNA - amygdala [nTPM]":"13.1","Brain RNA - basal ganglia [nTPM]":"15.1","Brain RNA - cerebellum [nTPM]":"15.6","Brain RNA - cerebral cortex [nTPM]":"17.3","Brain RNA - hippocampal formation [nTPM]":"14.7","Brain RNA - hypothalamus [nTPM]":"14.9","Brain RNA - medulla oblongata [nTPM]":"15.3","Brain RNA - midbrain [nTPM]":"13.7","Brain RNA - pons [nTPM]":"15.8","Brain RNA - spinal cord [nTPM]":"15.3","Brain RNA - thalamus [nTPM]":"13.8","Brain RNA - white matter [nTPM]":"22.4","Single Cell Type RNA - Adipocytes [nTPM]":"16.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.9","Single Cell Type RNA - Astrocytes [nTPM]":"47.0","Single Cell Type RNA - B-cells [nTPM]":"24.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"36.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"19.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.6","Single Cell Type RNA - Bipolar cells [nTPM]":"23.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"31.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"16.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"31.8","Single Cell Type RNA - dendritic cells [nTPM]":"17.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"17.6","Single Cell Type RNA - Early spermatids [nTPM]":"3.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.8","Single Cell Type RNA - Endothelial cells [nTPM]":"21.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.1","Single Cell Type RNA - Erythroid cells [nTPM]":"14.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"85.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"20.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"34.6","Single Cell Type RNA - Fibroblasts [nTPM]":"23.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.8","Single Cell Type RNA - granulocytes [nTPM]":"13.9","Single Cell Type RNA - Granulosa cells [nTPM]":"25.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.7","Single Cell Type RNA - Hepatocytes [nTPM]":"20.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.3","Single Cell Type RNA - Horizontal cells [nTPM]":"28.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"63.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.7","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"27.3","Single Cell Type RNA - Langerhans cells [nTPM]":"24.6","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"26.8","Single Cell Type RNA - Macrophages [nTPM]":"21.7","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"36.5","Single Cell Type RNA - monocytes [nTPM]":"35.2","Single Cell Type RNA - Muller glia cells [nTPM]":"19.6","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"50.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"137.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.1","Single Cell Type RNA - Paneth cells [nTPM]":"9.1","Single Cell Type RNA - Peritubular cells [nTPM]":"41.0","Single Cell Type RNA - Plasma cells [nTPM]":"18.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.5","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"28.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.5","Single Cell Type RNA - Spermatocytes [nTPM]":"25.9","Single Cell Type RNA - Spermatogonia [nTPM]":"24.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"37.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"48.4","Single Cell Type RNA - T-cells [nTPM]":"22.7","Single Cell Type RNA - Theca cells [nTPM]":"18.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.1","Single Cell Type RNA - Urothelial cells [nTPM]":"24.8"},{"Gene":"MAP3K9","Gene synonym":["MEKK9","MLK1","PRKE1"],"Ensembl":"ENSG00000006432","Gene description":"Mitogen-activated protein kinase kinase kinase 9","Uniprot":["P80192"],"Chromosome":"14","Position":"70722526-70809534","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Stress response","Transcription","Transcription regulation"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"22.7","retina":"9.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"49.6","Inhibitory neurons":"58.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"22.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000942"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA000942":"AB_1079360"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"1.0","Tissue RNA - amygdala [nTPM]":"3.3","Tissue RNA - appendix [nTPM]":"1.0","Tissue RNA - basal ganglia [nTPM]":"4.6","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"1.3","Tissue RNA - cerebellum [nTPM]":"10.7","Tissue RNA - cerebral cortex [nTPM]":"22.7","Tissue RNA - cervix [nTPM]":"0.9","Tissue RNA - choroid plexus [nTPM]":"0.4","Tissue RNA - colon [nTPM]":"1.5","Tissue RNA - duodenum [nTPM]":"1.5","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"1.5","Tissue RNA - esophagus [nTPM]":"5.1","Tissue RNA - fallopian tube [nTPM]":"1.0","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"4.0","Tissue RNA - hypothalamus [nTPM]":"3.2","Tissue RNA - kidney [nTPM]":"1.4","Tissue RNA - liver [nTPM]":"0.7","Tissue RNA - lung [nTPM]":"1.9","Tissue RNA - lymph node [nTPM]":"1.4","Tissue RNA - medulla oblongata [nTPM]":"8.6","Tissue RNA - midbrain [nTPM]":"3.0","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"2.2","Tissue RNA - parathyroid gland [nTPM]":"2.7","Tissue RNA - pituitary gland [nTPM]":"1.1","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"7.7","Tissue RNA - prostate [nTPM]":"0.9","Tissue RNA - rectum [nTPM]":"1.5","Tissue RNA - retina [nTPM]":"9.6","Tissue RNA - salivary gland [nTPM]":"1.7","Tissue RNA - seminal vesicle [nTPM]":"0.5","Tissue RNA - skeletal muscle [nTPM]":"0.8","Tissue RNA - skin 1 [nTPM]":"4.0","Tissue RNA - small intestine [nTPM]":"1.4","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"0.9","Tissue RNA - stomach 1 [nTPM]":"1.6","Tissue RNA - testis [nTPM]":"5.5","Tissue RNA - thalamus [nTPM]":"10.0","Tissue RNA - thymus [nTPM]":"0.9","Tissue RNA - thyroid gland [nTPM]":"2.7","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"3.6","Tissue RNA - urinary bladder [nTPM]":"0.7","Tissue RNA - vagina [nTPM]":"1.8","Tissue RNA - white matter [nTPM]":"6.8","Cell RNA - A-431 [nTPM]":"22.3","Cell RNA - A549 [nTPM]":"10.5","Cell RNA - AF22 [nTPM]":"2.0","Cell RNA - AN3-CA [nTPM]":"2.5","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"6.7","Cell RNA - BJ [nTPM]":"0.5","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.9","Cell RNA - CACO-2 [nTPM]":"7.8","Cell RNA - CAPAN-2 [nTPM]":"8.6","Cell RNA - Daudi [nTPM]":"4.5","Cell RNA - EFO-21 [nTPM]":"2.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"4.7","Cell RNA - HaCaT [nTPM]":"10.3","Cell RNA - HAP1 [nTPM]":"6.5","Cell RNA - HBEC3-KT [nTPM]":"12.8","Cell RNA - HBF TERT88 [nTPM]":"2.2","Cell RNA - HDLM-2 [nTPM]":"3.0","Cell RNA - HEK 293 [nTPM]":"1.7","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"4.1","Cell RNA - Hep G2 [nTPM]":"5.2","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"0.9","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"6.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.5","Cell RNA - hTERT-HME1 [nTPM]":"12.7","Cell RNA - hTERT-RPE1 [nTPM]":"3.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"4.1","Cell RNA - K-562 [nTPM]":"1.7","Cell RNA - Karpas-707 [nTPM]":"1.0","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"9.4","Cell RNA - MOLT-4 [nTPM]":"3.7","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"4.2","Cell RNA - OE19 [nTPM]":"9.0","Cell RNA - PC-3 [nTPM]":"4.5","Cell RNA - REH [nTPM]":"1.3","Cell RNA - RH-30 [nTPM]":"3.9","Cell RNA - RPMI-8226 [nTPM]":"0.9","Cell RNA - RPTEC TERT1 [nTPM]":"4.6","Cell RNA - RT4 [nTPM]":"10.9","Cell RNA - SCLC-21H [nTPM]":"13.8","Cell RNA - SH-SY5Y [nTPM]":"3.0","Cell RNA - SiHa [nTPM]":"6.3","Cell RNA - SK-BR-3 [nTPM]":"7.7","Cell RNA - SK-MEL-30 [nTPM]":"1.2","Cell RNA - SuSa [nTPM]":"3.7","Cell RNA - T-47d [nTPM]":"6.9","Cell RNA - THP-1 [nTPM]":"0.8","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"8.5","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"3.5","Cell RNA - U-266\/70 [nTPM]":"2.2","Cell RNA - U-266\/84 [nTPM]":"5.6","Cell RNA - U-698 [nTPM]":"2.4","Cell RNA - U-87 MG [nTPM]":"3.4","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"1.4","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.3","Brain RNA - basal ganglia [nTPM]":"4.6","Brain RNA - cerebellum [nTPM]":"10.7","Brain RNA - cerebral cortex [nTPM]":"22.7","Brain RNA - hippocampal formation [nTPM]":"4.0","Brain RNA - hypothalamus [nTPM]":"3.2","Brain RNA - medulla oblongata [nTPM]":"8.6","Brain RNA - midbrain [nTPM]":"3.0","Brain RNA - pons [nTPM]":"7.7","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"10.0","Brain RNA - white matter [nTPM]":"6.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.4","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"3.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"17.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"12.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.8","Single Cell Type RNA - dendritic cells [nTPM]":"1.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.1","Single Cell Type RNA - Early spermatids [nTPM]":"19.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"49.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.6","Single Cell Type RNA - Fibroblasts [nTPM]":"1.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"1.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"4.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.2","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"58.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"1.9","Single Cell Type RNA - Late spermatids [nTPM]":"20.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"0.4","Single Cell Type RNA - Muller glia cells [nTPM]":"3.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.1","Single Cell Type RNA - Paneth cells [nTPM]":"3.9","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.3","Single Cell Type RNA - Spermatocytes [nTPM]":"8.0","Single Cell Type RNA - Spermatogonia [nTPM]":"8.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.0","Single Cell Type RNA - T-cells [nTPM]":"3.7","Single Cell Type RNA - Theca cells [nTPM]":"6.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.8","Single Cell Type RNA - Urothelial cells [nTPM]":"27.9"},{"Gene":"MAPK10","Gene synonym":["JNK3","p493F12","p54bSAPK","PRKM10"],"Ensembl":"ENSG00000109339","Gene description":"Mitogen-activated protein kinase 10","Uniprot":["P53779"],"Chromosome":"4","Position":"85990007-86594625","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["Biological rhythms"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"91.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"902.0","Excitatory neurons":"1018.9","Inhibitory neurons":"727.8","Late spermatids":"400.5","Oligodendrocyte precursor cells":"596.6","Oligodendrocytes":"302.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"AF22":"155.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022625"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022625":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.11e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.57e-4"},"Tissue RNA - adipose tissue [nTPM]":"26.1","Tissue RNA - adrenal gland [nTPM]":"15.6","Tissue RNA - amygdala [nTPM]":"45.2","Tissue RNA - appendix [nTPM]":"5.1","Tissue RNA - basal ganglia [nTPM]":"61.6","Tissue RNA - bone marrow [nTPM]":"14.5","Tissue RNA - breast [nTPM]":"7.4","Tissue RNA - cerebellum [nTPM]":"25.4","Tissue RNA - cerebral cortex [nTPM]":"91.3","Tissue RNA - cervix [nTPM]":"17.5","Tissue RNA - choroid plexus [nTPM]":"23.5","Tissue RNA - colon [nTPM]":"5.7","Tissue RNA - duodenum [nTPM]":"3.6","Tissue RNA - endometrium 1 [nTPM]":"14.5","Tissue RNA - epididymis [nTPM]":"18.8","Tissue RNA - esophagus [nTPM]":"9.8","Tissue RNA - fallopian tube [nTPM]":"15.8","Tissue RNA - gallbladder [nTPM]":"13.8","Tissue RNA - heart muscle [nTPM]":"6.9","Tissue RNA - hippocampal formation [nTPM]":"60.4","Tissue RNA - hypothalamus [nTPM]":"24.9","Tissue RNA - kidney [nTPM]":"20.4","Tissue RNA - liver [nTPM]":"3.2","Tissue RNA - lung [nTPM]":"8.6","Tissue RNA - lymph node [nTPM]":"5.2","Tissue RNA - medulla oblongata [nTPM]":"29.0","Tissue RNA - midbrain [nTPM]":"36.2","Tissue RNA - ovary [nTPM]":"14.7","Tissue RNA - pancreas [nTPM]":"7.4","Tissue RNA - parathyroid gland [nTPM]":"10.3","Tissue RNA - pituitary gland [nTPM]":"25.5","Tissue RNA - placenta [nTPM]":"4.3","Tissue RNA - pons [nTPM]":"31.4","Tissue RNA - prostate [nTPM]":"22.4","Tissue RNA - rectum [nTPM]":"5.4","Tissue RNA - retina [nTPM]":"18.3","Tissue RNA - salivary gland [nTPM]":"4.7","Tissue RNA - seminal vesicle [nTPM]":"24.2","Tissue RNA - skeletal muscle [nTPM]":"2.6","Tissue RNA - skin 1 [nTPM]":"4.6","Tissue RNA - small intestine [nTPM]":"5.1","Tissue RNA - smooth muscle [nTPM]":"15.5","Tissue RNA - spinal cord [nTPM]":"24.9","Tissue RNA - spleen [nTPM]":"7.4","Tissue RNA - stomach 1 [nTPM]":"6.6","Tissue RNA - testis [nTPM]":"26.4","Tissue RNA - thalamus [nTPM]":"39.2","Tissue RNA - thymus [nTPM]":"3.4","Tissue RNA - thyroid gland [nTPM]":"20.5","Tissue RNA - tongue [nTPM]":"4.2","Tissue RNA - tonsil [nTPM]":"4.6","Tissue RNA - urinary bladder [nTPM]":"14.0","Tissue RNA - vagina [nTPM]":"18.4","Tissue RNA - white matter [nTPM]":"55.6","Cell RNA - A-431 [nTPM]":"2.9","Cell RNA - A549 [nTPM]":"4.9","Cell RNA - AF22 [nTPM]":"155.0","Cell RNA - AN3-CA [nTPM]":"4.8","Cell RNA - ASC diff [nTPM]":"4.1","Cell RNA - ASC TERT1 [nTPM]":"3.6","Cell RNA - BEWO [nTPM]":"5.6","Cell RNA - BJ [nTPM]":"3.2","Cell RNA - BJ hTERT+ [nTPM]":"2.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.2","Cell RNA - CACO-2 [nTPM]":"3.3","Cell RNA - CAPAN-2 [nTPM]":"4.4","Cell RNA - Daudi [nTPM]":"7.1","Cell RNA - EFO-21 [nTPM]":"5.1","Cell RNA - fHDF\/TERT166 [nTPM]":"1.9","Cell RNA - GAMG [nTPM]":"3.8","Cell RNA - HaCaT [nTPM]":"9.4","Cell RNA - HAP1 [nTPM]":"1.8","Cell RNA - HBEC3-KT [nTPM]":"4.2","Cell RNA - HBF TERT88 [nTPM]":"4.3","Cell RNA - HDLM-2 [nTPM]":"4.9","Cell RNA - HEK 293 [nTPM]":"4.0","Cell RNA - HEL [nTPM]":"5.7","Cell RNA - HeLa [nTPM]":"7.3","Cell RNA - Hep G2 [nTPM]":"4.6","Cell RNA - HHSteC [nTPM]":"3.6","Cell RNA - HL-60 [nTPM]":"2.7","Cell RNA - HMC-1 [nTPM]":"3.1","Cell RNA - HSkMC [nTPM]":"4.1","Cell RNA - hTCEpi [nTPM]":"1.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.7","Cell RNA - hTERT-HME1 [nTPM]":"5.0","Cell RNA - hTERT-RPE1 [nTPM]":"5.5","Cell RNA - HUVEC TERT2 [nTPM]":"3.5","Cell RNA - JURKAT [nTPM]":"4.8","Cell RNA - K-562 [nTPM]":"5.2","Cell RNA - Karpas-707 [nTPM]":"27.9","Cell RNA - LHCN-M2 [nTPM]":"1.7","Cell RNA - MCF7 [nTPM]":"3.5","Cell RNA - MOLT-4 [nTPM]":"4.4","Cell RNA - NB-4 [nTPM]":"3.1","Cell RNA - NTERA-2 [nTPM]":"8.8","Cell RNA - OE19 [nTPM]":"0.7","Cell RNA - PC-3 [nTPM]":"3.2","Cell RNA - REH [nTPM]":"4.9","Cell RNA - RH-30 [nTPM]":"4.0","Cell RNA - RPMI-8226 [nTPM]":"2.5","Cell RNA - RPTEC TERT1 [nTPM]":"10.7","Cell RNA - RT4 [nTPM]":"16.9","Cell RNA - SCLC-21H [nTPM]":"9.2","Cell RNA - SH-SY5Y [nTPM]":"8.4","Cell RNA - SiHa [nTPM]":"3.3","Cell RNA - SK-BR-3 [nTPM]":"5.9","Cell RNA - SK-MEL-30 [nTPM]":"2.2","Cell RNA - SuSa [nTPM]":"5.0","Cell RNA - T-47d [nTPM]":"8.8","Cell RNA - THP-1 [nTPM]":"3.3","Cell RNA - TIME [nTPM]":"7.5","Cell RNA - U-138 MG [nTPM]":"6.3","Cell RNA - U-2 OS [nTPM]":"6.4","Cell RNA - U-2197 [nTPM]":"3.0","Cell RNA - U-251 MG [nTPM]":"2.7","Cell RNA - U-266\/70 [nTPM]":"8.2","Cell RNA - U-266\/84 [nTPM]":"5.1","Cell RNA - U-698 [nTPM]":"4.4","Cell RNA - U-87 MG [nTPM]":"9.9","Cell RNA - U-937 [nTPM]":"3.5","Cell RNA - WM-115 [nTPM]":"3.8","Blood RNA - basophil [nTPM]":"3.3","Blood RNA - classical monocyte [nTPM]":"0.7","Blood RNA - eosinophil [nTPM]":"1.2","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.7","Blood RNA - memory CD8 T-cell [nTPM]":"1.0","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.4","Blood RNA - neutrophil [nTPM]":"4.4","Blood RNA - NK-cell [nTPM]":"1.2","Blood RNA - non-classical monocyte [nTPM]":"0.7","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"45.2","Brain RNA - basal ganglia [nTPM]":"61.6","Brain RNA - cerebellum [nTPM]":"25.4","Brain RNA - cerebral cortex [nTPM]":"91.3","Brain RNA - hippocampal formation [nTPM]":"60.4","Brain RNA - hypothalamus [nTPM]":"24.9","Brain RNA - medulla oblongata [nTPM]":"29.0","Brain RNA - midbrain [nTPM]":"36.2","Brain RNA - pons [nTPM]":"31.4","Brain RNA - spinal cord [nTPM]":"24.9","Brain RNA - thalamus [nTPM]":"39.2","Brain RNA - white matter [nTPM]":"55.6","Single Cell Type RNA - Adipocytes [nTPM]":"4.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"33.8","Single Cell Type RNA - Astrocytes [nTPM]":"902.0","Single Cell Type RNA - B-cells [nTPM]":"1.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"26.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"12.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"2.4","Single Cell Type RNA - Early spermatids [nTPM]":"219.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"61.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"25.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1018.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"16.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.1","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"6.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"38.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"727.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"400.5","Single Cell Type RNA - Leydig cells [nTPM]":"26.4","Single Cell Type RNA - Macrophages [nTPM]":"1.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"185.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"15.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"596.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"302.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"54.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"68.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.5","Single Cell Type RNA - Spermatocytes [nTPM]":"10.5","Single Cell Type RNA - Spermatogonia [nTPM]":"5.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"28.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"22.6"},{"Gene":"MAPK12","Gene synonym":["ERK6","p38gamma","PRKM12","SAPK-3","SAPK3"],"Ensembl":"ENSG00000188130","Gene description":"Mitogen-activated protein kinase 12","Uniprot":["P53778"],"Chromosome":"22","Position":"50245450-50261716","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","Stress response","Transcription","Transcription regulation"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"skeletal muscle":"279.7","tongue":"120.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"23.1","Astrocytes":"22.9","Endothelial cells":"15.8","Hepatic stellate cells":"20.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebellum":"31.6"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025483","HPA054562"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB025483":null,"HPA054562":"AB_2682524"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.00e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-3"},"Tissue RNA - adipose tissue [nTPM]":"11.0","Tissue RNA - adrenal gland [nTPM]":"2.3","Tissue RNA - amygdala [nTPM]":"15.6","Tissue RNA - appendix [nTPM]":"3.8","Tissue RNA - basal ganglia [nTPM]":"16.5","Tissue RNA - bone marrow [nTPM]":"1.3","Tissue RNA - breast [nTPM]":"7.9","Tissue RNA - cerebellum [nTPM]":"15.5","Tissue RNA - cerebral cortex [nTPM]":"21.2","Tissue RNA - cervix [nTPM]":"11.4","Tissue RNA - choroid plexus [nTPM]":"9.2","Tissue RNA - colon [nTPM]":"4.7","Tissue RNA - duodenum [nTPM]":"3.5","Tissue RNA - endometrium 1 [nTPM]":"19.0","Tissue RNA - epididymis [nTPM]":"9.8","Tissue RNA - esophagus [nTPM]":"6.3","Tissue RNA - fallopian tube [nTPM]":"11.2","Tissue RNA - gallbladder [nTPM]":"4.4","Tissue RNA - heart muscle [nTPM]":"15.7","Tissue RNA - hippocampal formation [nTPM]":"15.1","Tissue RNA - hypothalamus [nTPM]":"16.5","Tissue RNA - kidney [nTPM]":"10.7","Tissue RNA - liver [nTPM]":"1.4","Tissue RNA - lung [nTPM]":"6.8","Tissue RNA - lymph node [nTPM]":"4.1","Tissue RNA - medulla oblongata [nTPM]":"17.1","Tissue RNA - midbrain [nTPM]":"14.9","Tissue RNA - ovary [nTPM]":"10.6","Tissue RNA - pancreas [nTPM]":"1.8","Tissue RNA - parathyroid gland [nTPM]":"4.3","Tissue RNA - pituitary gland [nTPM]":"25.1","Tissue RNA - placenta [nTPM]":"4.1","Tissue RNA - pons [nTPM]":"14.6","Tissue RNA - prostate [nTPM]":"10.0","Tissue RNA - rectum [nTPM]":"1.1","Tissue RNA - retina [nTPM]":"1.4","Tissue RNA - salivary gland [nTPM]":"4.3","Tissue RNA - seminal vesicle [nTPM]":"6.9","Tissue RNA - skeletal muscle [nTPM]":"279.7","Tissue RNA - skin 1 [nTPM]":"1.5","Tissue RNA - small intestine [nTPM]":"4.4","Tissue RNA - smooth muscle [nTPM]":"8.6","Tissue RNA - spinal cord [nTPM]":"14.6","Tissue RNA - spleen [nTPM]":"4.3","Tissue RNA - stomach 1 [nTPM]":"5.0","Tissue RNA - testis [nTPM]":"4.6","Tissue RNA - thalamus [nTPM]":"15.2","Tissue RNA - thymus [nTPM]":"0.9","Tissue RNA - thyroid gland [nTPM]":"3.2","Tissue RNA - tongue [nTPM]":"120.9","Tissue RNA - tonsil [nTPM]":"1.4","Tissue RNA - urinary bladder [nTPM]":"6.0","Tissue RNA - vagina [nTPM]":"5.9","Tissue RNA - white matter [nTPM]":"13.9","Cell RNA - A-431 [nTPM]":"23.2","Cell RNA - A549 [nTPM]":"13.9","Cell RNA - AF22 [nTPM]":"5.3","Cell RNA - AN3-CA [nTPM]":"16.3","Cell RNA - ASC diff [nTPM]":"12.4","Cell RNA - ASC TERT1 [nTPM]":"13.5","Cell RNA - BEWO [nTPM]":"7.5","Cell RNA - BJ [nTPM]":"17.5","Cell RNA - BJ hTERT+ [nTPM]":"15.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"28.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"18.3","Cell RNA - CACO-2 [nTPM]":"19.6","Cell RNA - CAPAN-2 [nTPM]":"7.2","Cell RNA - Daudi [nTPM]":"45.1","Cell RNA - EFO-21 [nTPM]":"23.4","Cell RNA - fHDF\/TERT166 [nTPM]":"19.6","Cell RNA - GAMG [nTPM]":"16.8","Cell RNA - HaCaT [nTPM]":"15.4","Cell RNA - HAP1 [nTPM]":"24.3","Cell RNA - HBEC3-KT [nTPM]":"3.4","Cell RNA - HBF TERT88 [nTPM]":"5.5","Cell RNA - HDLM-2 [nTPM]":"12.8","Cell RNA - HEK 293 [nTPM]":"34.0","Cell RNA - HEL [nTPM]":"29.2","Cell RNA - HeLa [nTPM]":"46.7","Cell RNA - Hep G2 [nTPM]":"24.9","Cell RNA - HHSteC [nTPM]":"37.7","Cell RNA - HL-60 [nTPM]":"28.4","Cell RNA - HMC-1 [nTPM]":"54.5","Cell RNA - HSkMC [nTPM]":"29.8","Cell RNA - hTCEpi [nTPM]":"6.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"16.8","Cell RNA - HUVEC TERT2 [nTPM]":"33.2","Cell RNA - JURKAT [nTPM]":"4.0","Cell RNA - K-562 [nTPM]":"26.3","Cell RNA - Karpas-707 [nTPM]":"38.5","Cell RNA - LHCN-M2 [nTPM]":"13.4","Cell RNA - MCF7 [nTPM]":"12.8","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"35.4","Cell RNA - NTERA-2 [nTPM]":"15.9","Cell RNA - OE19 [nTPM]":"7.6","Cell RNA - PC-3 [nTPM]":"22.5","Cell RNA - REH [nTPM]":"41.4","Cell RNA - RH-30 [nTPM]":"14.2","Cell RNA - RPMI-8226 [nTPM]":"43.9","Cell RNA - RPTEC TERT1 [nTPM]":"17.5","Cell RNA - RT4 [nTPM]":"3.0","Cell RNA - SCLC-21H [nTPM]":"18.0","Cell RNA - SH-SY5Y [nTPM]":"6.5","Cell RNA - SiHa [nTPM]":"13.3","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"22.1","Cell RNA - SuSa [nTPM]":"4.2","Cell RNA - T-47d [nTPM]":"7.1","Cell RNA - THP-1 [nTPM]":"29.6","Cell RNA - TIME [nTPM]":"18.7","Cell RNA - U-138 MG [nTPM]":"28.5","Cell RNA - U-2 OS [nTPM]":"26.1","Cell RNA - U-2197 [nTPM]":"6.6","Cell RNA - U-251 MG [nTPM]":"11.2","Cell RNA - U-266\/70 [nTPM]":"9.3","Cell RNA - U-266\/84 [nTPM]":"7.3","Cell RNA - U-698 [nTPM]":"24.5","Cell RNA - U-87 MG [nTPM]":"7.2","Cell RNA - U-937 [nTPM]":"24.7","Cell RNA - WM-115 [nTPM]":"11.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"15.6","Brain RNA - basal ganglia [nTPM]":"16.5","Brain RNA - cerebellum [nTPM]":"15.5","Brain RNA - cerebral cortex [nTPM]":"21.2","Brain RNA - hippocampal formation [nTPM]":"15.1","Brain RNA - hypothalamus [nTPM]":"16.5","Brain RNA - medulla oblongata [nTPM]":"17.1","Brain RNA - midbrain [nTPM]":"14.9","Brain RNA - pons [nTPM]":"14.6","Brain RNA - spinal cord [nTPM]":"14.6","Brain RNA - thalamus [nTPM]":"15.2","Brain RNA - white matter [nTPM]":"13.9","Single Cell Type RNA - Adipocytes [nTPM]":"23.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.2","Single Cell Type RNA - Astrocytes [nTPM]":"22.9","Single Cell Type RNA - B-cells [nTPM]":"1.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"5.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"0.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.0","Single Cell Type RNA - Endothelial cells [nTPM]":"15.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.8","Single Cell Type RNA - Fibroblasts [nTPM]":"5.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.3","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"2.2","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.9","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"2.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"8.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"2.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"12.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"2.2","Single Cell Type RNA - Theca cells [nTPM]":"3.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"MAPKAPK3","Gene synonym":["3pK","MAPKAP3","MK-3","MK3"],"Ensembl":"ENSG00000114738","Gene description":"MAPK activated protein kinase 3","Uniprot":["Q16644"],"Chromosome":"3","Position":"50611520-50649291","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"bone marrow":"106.5","heart muscle":"256.3","skeletal muscle":"224.2","tongue":"284.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"226.6","Hofbauer cells":"102.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"142.8","granulocytes":"126.3","monocytes":"341.5"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058275"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA058275":"AB_2683663"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.08e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.77e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.90e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Tissue RNA - adipose tissue [nTPM]":"15.3","Tissue RNA - adrenal gland [nTPM]":"43.3","Tissue RNA - amygdala [nTPM]":"18.0","Tissue RNA - appendix [nTPM]":"29.8","Tissue RNA - basal ganglia [nTPM]":"19.6","Tissue RNA - bone marrow [nTPM]":"106.5","Tissue RNA - breast [nTPM]":"15.8","Tissue RNA - cerebellum [nTPM]":"19.2","Tissue RNA - cerebral cortex [nTPM]":"19.2","Tissue RNA - cervix [nTPM]":"15.0","Tissue RNA - choroid plexus [nTPM]":"21.3","Tissue RNA - colon [nTPM]":"19.7","Tissue RNA - duodenum [nTPM]":"30.2","Tissue RNA - endometrium 1 [nTPM]":"11.3","Tissue RNA - epididymis [nTPM]":"10.3","Tissue RNA - esophagus [nTPM]":"49.6","Tissue RNA - fallopian tube [nTPM]":"15.1","Tissue RNA - gallbladder [nTPM]":"12.1","Tissue RNA - heart muscle [nTPM]":"256.3","Tissue RNA - hippocampal formation [nTPM]":"18.0","Tissue RNA - hypothalamus [nTPM]":"19.7","Tissue RNA - kidney [nTPM]":"40.0","Tissue RNA - liver [nTPM]":"18.7","Tissue RNA - lung [nTPM]":"28.2","Tissue RNA - lymph node [nTPM]":"21.7","Tissue RNA - medulla oblongata [nTPM]":"23.6","Tissue RNA - midbrain [nTPM]":"20.5","Tissue RNA - ovary [nTPM]":"14.2","Tissue RNA - pancreas [nTPM]":"36.2","Tissue RNA - parathyroid gland [nTPM]":"47.2","Tissue RNA - pituitary gland [nTPM]":"23.5","Tissue RNA - placenta [nTPM]":"13.9","Tissue RNA - pons [nTPM]":"22.5","Tissue RNA - prostate [nTPM]":"18.4","Tissue RNA - rectum [nTPM]":"20.0","Tissue RNA - retina [nTPM]":"4.7","Tissue RNA - salivary gland [nTPM]":"27.7","Tissue RNA - seminal vesicle [nTPM]":"12.6","Tissue RNA - skeletal muscle [nTPM]":"224.2","Tissue RNA - skin 1 [nTPM]":"53.4","Tissue RNA - small intestine [nTPM]":"24.2","Tissue RNA - smooth muscle [nTPM]":"15.9","Tissue RNA - spinal cord [nTPM]":"21.6","Tissue RNA - spleen [nTPM]":"25.3","Tissue RNA - stomach 1 [nTPM]":"27.6","Tissue RNA - testis [nTPM]":"9.2","Tissue RNA - thalamus [nTPM]":"21.1","Tissue RNA - thymus [nTPM]":"42.0","Tissue RNA - thyroid gland [nTPM]":"41.2","Tissue RNA - tongue [nTPM]":"284.3","Tissue RNA - tonsil [nTPM]":"24.2","Tissue RNA - urinary bladder [nTPM]":"20.3","Tissue RNA - vagina [nTPM]":"22.2","Tissue RNA - white matter [nTPM]":"21.6","Cell RNA - A-431 [nTPM]":"99.6","Cell RNA - A549 [nTPM]":"30.3","Cell RNA - AF22 [nTPM]":"12.4","Cell RNA - AN3-CA [nTPM]":"35.9","Cell RNA - ASC diff [nTPM]":"18.4","Cell RNA - ASC TERT1 [nTPM]":"45.7","Cell RNA - BEWO [nTPM]":"27.9","Cell RNA - BJ [nTPM]":"23.8","Cell RNA - BJ hTERT+ [nTPM]":"33.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"35.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"30.3","Cell RNA - CACO-2 [nTPM]":"47.1","Cell RNA - CAPAN-2 [nTPM]":"90.2","Cell RNA - Daudi [nTPM]":"39.8","Cell RNA - EFO-21 [nTPM]":"23.5","Cell RNA - fHDF\/TERT166 [nTPM]":"79.5","Cell RNA - GAMG [nTPM]":"88.5","Cell RNA - HaCaT [nTPM]":"34.6","Cell RNA - HAP1 [nTPM]":"85.9","Cell RNA - HBEC3-KT [nTPM]":"92.7","Cell RNA - HBF TERT88 [nTPM]":"31.9","Cell RNA - HDLM-2 [nTPM]":"88.3","Cell RNA - HEK 293 [nTPM]":"22.3","Cell RNA - HEL [nTPM]":"209.5","Cell RNA - HeLa [nTPM]":"40.6","Cell RNA - Hep G2 [nTPM]":"43.5","Cell RNA - HHSteC [nTPM]":"36.8","Cell RNA - HL-60 [nTPM]":"152.1","Cell RNA - HMC-1 [nTPM]":"106.4","Cell RNA - HSkMC [nTPM]":"36.9","Cell RNA - hTCEpi [nTPM]":"57.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"83.1","Cell RNA - hTERT-HME1 [nTPM]":"112.2","Cell RNA - hTERT-RPE1 [nTPM]":"35.6","Cell RNA - HUVEC TERT2 [nTPM]":"31.9","Cell RNA - JURKAT [nTPM]":"70.2","Cell RNA - K-562 [nTPM]":"59.7","Cell RNA - Karpas-707 [nTPM]":"25.4","Cell RNA - LHCN-M2 [nTPM]":"76.1","Cell RNA - MCF7 [nTPM]":"40.5","Cell RNA - MOLT-4 [nTPM]":"65.3","Cell RNA - NB-4 [nTPM]":"153.3","Cell RNA - NTERA-2 [nTPM]":"46.4","Cell RNA - OE19 [nTPM]":"34.6","Cell RNA - PC-3 [nTPM]":"127.0","Cell RNA - REH [nTPM]":"28.5","Cell RNA - RH-30 [nTPM]":"29.9","Cell RNA - RPMI-8226 [nTPM]":"60.1","Cell RNA - RPTEC TERT1 [nTPM]":"165.5","Cell RNA - RT4 [nTPM]":"56.2","Cell RNA - SCLC-21H [nTPM]":"23.0","Cell RNA - SH-SY5Y [nTPM]":"16.5","Cell RNA - SiHa [nTPM]":"21.3","Cell RNA - SK-BR-3 [nTPM]":"58.9","Cell RNA - SK-MEL-30 [nTPM]":"27.7","Cell RNA - SuSa [nTPM]":"20.6","Cell RNA - T-47d [nTPM]":"37.8","Cell RNA - THP-1 [nTPM]":"93.4","Cell RNA - TIME [nTPM]":"23.8","Cell RNA - U-138 MG [nTPM]":"28.1","Cell RNA - U-2 OS [nTPM]":"64.5","Cell RNA - U-2197 [nTPM]":"146.4","Cell RNA - U-251 MG [nTPM]":"59.5","Cell RNA - U-266\/70 [nTPM]":"17.2","Cell RNA - U-266\/84 [nTPM]":"33.7","Cell RNA - U-698 [nTPM]":"33.1","Cell RNA - U-87 MG [nTPM]":"148.3","Cell RNA - U-937 [nTPM]":"234.7","Cell RNA - WM-115 [nTPM]":"11.8","Blood RNA - basophil [nTPM]":"45.3","Blood RNA - classical monocyte [nTPM]":"169.5","Blood RNA - eosinophil [nTPM]":"126.3","Blood RNA - gdT-cell [nTPM]":"27.6","Blood RNA - intermediate monocyte [nTPM]":"271.6","Blood RNA - MAIT T-cell [nTPM]":"27.3","Blood RNA - memory B-cell [nTPM]":"15.1","Blood RNA - memory CD4 T-cell [nTPM]":"30.9","Blood RNA - memory CD8 T-cell [nTPM]":"32.1","Blood RNA - myeloid DC [nTPM]":"142.8","Blood RNA - naive B-cell [nTPM]":"8.8","Blood RNA - naive CD4 T-cell [nTPM]":"23.9","Blood RNA - naive CD8 T-cell [nTPM]":"27.8","Blood RNA - neutrophil [nTPM]":"104.4","Blood RNA - NK-cell [nTPM]":"42.1","Blood RNA - non-classical monocyte [nTPM]":"341.5","Blood RNA - plasmacytoid DC [nTPM]":"91.2","Blood RNA - T-reg [nTPM]":"28.0","Blood RNA - total PBMC [nTPM]":"132.6","Brain RNA - amygdala [nTPM]":"18.0","Brain RNA - basal ganglia [nTPM]":"19.6","Brain RNA - cerebellum [nTPM]":"19.2","Brain RNA - cerebral cortex [nTPM]":"19.2","Brain RNA - hippocampal formation [nTPM]":"18.0","Brain RNA - hypothalamus [nTPM]":"19.7","Brain RNA - medulla oblongata [nTPM]":"23.6","Brain RNA - midbrain [nTPM]":"20.5","Brain RNA - pons [nTPM]":"22.5","Brain RNA - spinal cord [nTPM]":"21.6","Brain RNA - thalamus [nTPM]":"21.1","Brain RNA - white matter [nTPM]":"21.6","Single Cell Type RNA - Adipocytes [nTPM]":"3.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.0","Single Cell Type RNA - Astrocytes [nTPM]":"8.5","Single Cell Type RNA - B-cells [nTPM]":"8.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"26.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.4","Single Cell Type RNA - Bipolar cells [nTPM]":"1.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"226.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"10.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.0","Single Cell Type RNA - dendritic cells [nTPM]":"38.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"64.6","Single Cell Type RNA - Ductal cells [nTPM]":"45.6","Single Cell Type RNA - Early spermatids [nTPM]":"34.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.7","Single Cell Type RNA - Endothelial cells [nTPM]":"7.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"19.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.4","Single Cell Type RNA - Fibroblasts [nTPM]":"14.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.4","Single Cell Type RNA - granulocytes [nTPM]":"36.2","Single Cell Type RNA - Granulosa cells [nTPM]":"8.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"14.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"102.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.4","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"68.0","Single Cell Type RNA - Langerhans cells [nTPM]":"23.9","Single Cell Type RNA - Late spermatids [nTPM]":"86.2","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"59.4","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"76.6","Single Cell Type RNA - Muller glia cells [nTPM]":"17.1","Single Cell Type RNA - NK-cells [nTPM]":"41.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"76.2","Single Cell Type RNA - Paneth cells [nTPM]":"15.6","Single Cell Type RNA - Peritubular cells [nTPM]":"3.4","Single Cell Type RNA - Plasma cells [nTPM]":"12.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"30.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"35.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.3","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.0","Single Cell Type RNA - Spermatocytes [nTPM]":"4.1","Single Cell Type RNA - Spermatogonia [nTPM]":"4.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"34.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.1","Single Cell Type RNA - T-cells [nTPM]":"24.3","Single Cell Type RNA - Theca cells [nTPM]":"22.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"28.2","Single Cell Type RNA - Urothelial cells [nTPM]":"33.5"},{"Gene":"MARCHF6","Gene synonym":["MARCH-VI","MARCH6","RNF176","TEB4"],"Ensembl":"ENSG00000145495","Gene description":"Membrane associated ring-CH-type finger 6","Uniprot":["O60337"],"Chromosome":"5","Position":"10353695-10440388","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"38.5","Cardiomyocytes":"102.5","Cytotrophoblasts":"54.4","dendritic cells":"25.8","Extravillous trophoblasts":"30.0","Hofbauer cells":"36.4","Syncytiotrophoblasts":"81.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040841","HPA063246"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA040841":"AB_2677162","HPA063246":"AB_2684970"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-3"},"Tissue RNA - adipose tissue [nTPM]":"22.1","Tissue RNA - adrenal gland [nTPM]":"25.5","Tissue RNA - amygdala [nTPM]":"16.1","Tissue RNA - appendix [nTPM]":"20.3","Tissue RNA - basal ganglia [nTPM]":"23.7","Tissue RNA - bone marrow [nTPM]":"76.5","Tissue RNA - breast [nTPM]":"25.9","Tissue RNA - cerebellum [nTPM]":"28.3","Tissue RNA - cerebral cortex [nTPM]":"20.7","Tissue RNA - cervix [nTPM]":"20.1","Tissue RNA - choroid plexus [nTPM]":"2.9","Tissue RNA - colon [nTPM]":"26.9","Tissue RNA - duodenum [nTPM]":"32.8","Tissue RNA - endometrium 1 [nTPM]":"22.7","Tissue RNA - epididymis [nTPM]":"25.5","Tissue RNA - esophagus [nTPM]":"20.9","Tissue RNA - fallopian tube [nTPM]":"24.9","Tissue RNA - gallbladder [nTPM]":"24.5","Tissue RNA - heart muscle [nTPM]":"30.8","Tissue RNA - hippocampal formation [nTPM]":"22.0","Tissue RNA - hypothalamus [nTPM]":"30.4","Tissue RNA - kidney [nTPM]":"34.1","Tissue RNA - liver [nTPM]":"32.5","Tissue RNA - lung [nTPM]":"25.1","Tissue RNA - lymph node [nTPM]":"24.7","Tissue RNA - medulla oblongata [nTPM]":"13.7","Tissue RNA - midbrain [nTPM]":"17.5","Tissue RNA - ovary [nTPM]":"36.0","Tissue RNA - pancreas [nTPM]":"39.3","Tissue RNA - parathyroid gland [nTPM]":"62.4","Tissue RNA - pituitary gland [nTPM]":"20.8","Tissue RNA - placenta [nTPM]":"22.8","Tissue RNA - pons [nTPM]":"16.9","Tissue RNA - prostate [nTPM]":"22.7","Tissue RNA - rectum [nTPM]":"19.8","Tissue RNA - retina [nTPM]":"36.6","Tissue RNA - salivary gland [nTPM]":"25.6","Tissue RNA - seminal vesicle [nTPM]":"23.8","Tissue RNA - skeletal muscle [nTPM]":"48.4","Tissue RNA - skin 1 [nTPM]":"24.8","Tissue RNA - small intestine [nTPM]":"30.3","Tissue RNA - smooth muscle [nTPM]":"18.9","Tissue RNA - spinal cord [nTPM]":"13.8","Tissue RNA - spleen [nTPM]":"28.2","Tissue RNA - stomach 1 [nTPM]":"30.2","Tissue RNA - testis [nTPM]":"29.9","Tissue RNA - thalamus [nTPM]":"27.9","Tissue RNA - thymus [nTPM]":"32.3","Tissue RNA - thyroid gland [nTPM]":"29.3","Tissue RNA - tongue [nTPM]":"51.8","Tissue RNA - tonsil [nTPM]":"23.3","Tissue RNA - urinary bladder [nTPM]":"23.7","Tissue RNA - vagina [nTPM]":"18.6","Tissue RNA - white matter [nTPM]":"33.5","Cell RNA - A-431 [nTPM]":"37.4","Cell RNA - A549 [nTPM]":"55.1","Cell RNA - AF22 [nTPM]":"90.1","Cell RNA - AN3-CA [nTPM]":"69.9","Cell RNA - ASC diff [nTPM]":"50.6","Cell RNA - ASC TERT1 [nTPM]":"40.4","Cell RNA - BEWO [nTPM]":"73.7","Cell RNA - BJ [nTPM]":"57.7","Cell RNA - BJ hTERT+ [nTPM]":"53.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"48.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"61.8","Cell RNA - CACO-2 [nTPM]":"52.8","Cell RNA - CAPAN-2 [nTPM]":"97.0","Cell RNA - Daudi [nTPM]":"39.4","Cell RNA - EFO-21 [nTPM]":"85.4","Cell RNA - fHDF\/TERT166 [nTPM]":"54.4","Cell RNA - GAMG [nTPM]":"67.2","Cell RNA - HaCaT [nTPM]":"52.3","Cell RNA - HAP1 [nTPM]":"48.2","Cell RNA - HBEC3-KT [nTPM]":"37.7","Cell RNA - HBF TERT88 [nTPM]":"65.4","Cell RNA - HDLM-2 [nTPM]":"82.9","Cell RNA - HEK 293 [nTPM]":"43.0","Cell RNA - HEL [nTPM]":"50.7","Cell RNA - HeLa [nTPM]":"179.7","Cell RNA - Hep G2 [nTPM]":"36.2","Cell RNA - HHSteC [nTPM]":"35.6","Cell RNA - HL-60 [nTPM]":"61.4","Cell RNA - HMC-1 [nTPM]":"54.6","Cell RNA - HSkMC [nTPM]":"47.4","Cell RNA - hTCEpi [nTPM]":"40.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"49.0","Cell RNA - hTERT-HME1 [nTPM]":"53.1","Cell RNA - hTERT-RPE1 [nTPM]":"50.0","Cell RNA - HUVEC TERT2 [nTPM]":"45.8","Cell RNA - JURKAT [nTPM]":"41.4","Cell RNA - K-562 [nTPM]":"62.1","Cell RNA - Karpas-707 [nTPM]":"85.1","Cell RNA - LHCN-M2 [nTPM]":"45.0","Cell RNA - MCF7 [nTPM]":"42.4","Cell RNA - MOLT-4 [nTPM]":"33.1","Cell RNA - NB-4 [nTPM]":"47.2","Cell RNA - NTERA-2 [nTPM]":"32.8","Cell RNA - OE19 [nTPM]":"29.9","Cell RNA - PC-3 [nTPM]":"38.5","Cell RNA - REH [nTPM]":"50.9","Cell RNA - RH-30 [nTPM]":"37.6","Cell RNA - RPMI-8226 [nTPM]":"57.0","Cell RNA - RPTEC TERT1 [nTPM]":"38.0","Cell RNA - RT4 [nTPM]":"72.4","Cell RNA - SCLC-21H [nTPM]":"38.7","Cell RNA - SH-SY5Y [nTPM]":"56.0","Cell RNA - SiHa [nTPM]":"107.2","Cell RNA - SK-BR-3 [nTPM]":"57.9","Cell RNA - SK-MEL-30 [nTPM]":"38.4","Cell RNA - SuSa [nTPM]":"41.3","Cell RNA - T-47d [nTPM]":"48.2","Cell RNA - THP-1 [nTPM]":"32.5","Cell RNA - TIME [nTPM]":"44.8","Cell RNA - U-138 MG [nTPM]":"58.4","Cell RNA - U-2 OS [nTPM]":"56.8","Cell RNA - U-2197 [nTPM]":"29.1","Cell RNA - U-251 MG [nTPM]":"43.7","Cell RNA - U-266\/70 [nTPM]":"59.3","Cell RNA - U-266\/84 [nTPM]":"94.1","Cell RNA - U-698 [nTPM]":"55.7","Cell RNA - U-87 MG [nTPM]":"43.1","Cell RNA - U-937 [nTPM]":"40.7","Cell RNA - WM-115 [nTPM]":"42.8","Blood RNA - basophil [nTPM]":"15.6","Blood RNA - classical monocyte [nTPM]":"7.4","Blood RNA - eosinophil [nTPM]":"12.6","Blood RNA - gdT-cell [nTPM]":"11.2","Blood RNA - intermediate monocyte [nTPM]":"8.4","Blood RNA - MAIT T-cell [nTPM]":"12.8","Blood RNA - memory B-cell [nTPM]":"11.7","Blood RNA - memory CD4 T-cell [nTPM]":"10.8","Blood RNA - memory CD8 T-cell [nTPM]":"11.0","Blood RNA - myeloid DC [nTPM]":"6.3","Blood RNA - naive B-cell [nTPM]":"9.6","Blood RNA - naive CD4 T-cell [nTPM]":"12.5","Blood RNA - naive CD8 T-cell [nTPM]":"12.4","Blood RNA - neutrophil [nTPM]":"12.1","Blood RNA - NK-cell [nTPM]":"9.1","Blood RNA - non-classical monocyte [nTPM]":"11.1","Blood RNA - plasmacytoid DC [nTPM]":"5.0","Blood RNA - T-reg [nTPM]":"10.4","Blood RNA - total PBMC [nTPM]":"9.1","Brain RNA - amygdala [nTPM]":"16.1","Brain RNA - basal ganglia [nTPM]":"23.7","Brain RNA - cerebellum [nTPM]":"28.3","Brain RNA - cerebral cortex [nTPM]":"20.7","Brain RNA - hippocampal formation [nTPM]":"22.0","Brain RNA - hypothalamus [nTPM]":"30.4","Brain RNA - medulla oblongata [nTPM]":"13.7","Brain RNA - midbrain [nTPM]":"17.5","Brain RNA - pons [nTPM]":"16.9","Brain RNA - spinal cord [nTPM]":"13.8","Brain RNA - thalamus [nTPM]":"27.9","Brain RNA - white matter [nTPM]":"33.5","Single Cell Type RNA - Adipocytes [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"13.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"102.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"54.4","Single Cell Type RNA - dendritic cells [nTPM]":"25.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"10.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"30.0","Single Cell Type RNA - Fibroblasts [nTPM]":"19.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"36.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"5.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"19.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"81.3","Single Cell Type RNA - T-cells [nTPM]":"5.8","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"MARK1","Gene synonym":["MARK","PAR-1C"],"Ensembl":"ENSG00000116141","Gene description":"Microtubule affinity regulating kinase 1","Uniprot":["Q9P0L2"],"Chromosome":"1","Position":"220528136-220664461","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Autism","Autism spectrum disorder"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"73.8","Excitatory neurons":"171.3","Inhibitory neurons":"170.1","Oligodendrocyte precursor cells":"167.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HAP1":"11.3","RT4":"33.7","SuSa":"12.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007421","HPA008061"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA007421":"AB_1079311","HPA008061":"AB_1079310"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.63e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.23e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.56e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.3","Tissue RNA - adrenal gland [nTPM]":"1.8","Tissue RNA - amygdala [nTPM]":"6.9","Tissue RNA - appendix [nTPM]":"1.4","Tissue RNA - basal ganglia [nTPM]":"7.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"4.9","Tissue RNA - cerebellum [nTPM]":"6.4","Tissue RNA - cerebral cortex [nTPM]":"10.0","Tissue RNA - cervix [nTPM]":"4.6","Tissue RNA - choroid plexus [nTPM]":"8.4","Tissue RNA - colon [nTPM]":"5.4","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"4.2","Tissue RNA - epididymis [nTPM]":"9.7","Tissue RNA - esophagus [nTPM]":"4.8","Tissue RNA - fallopian tube [nTPM]":"3.3","Tissue RNA - gallbladder [nTPM]":"1.7","Tissue RNA - heart muscle [nTPM]":"8.0","Tissue RNA - hippocampal formation [nTPM]":"7.4","Tissue RNA - hypothalamus [nTPM]":"6.7","Tissue RNA - kidney [nTPM]":"2.3","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"3.1","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"6.4","Tissue RNA - midbrain [nTPM]":"6.8","Tissue RNA - ovary [nTPM]":"1.7","Tissue RNA - pancreas [nTPM]":"0.9","Tissue RNA - parathyroid gland [nTPM]":"2.4","Tissue RNA - pituitary gland [nTPM]":"6.9","Tissue RNA - placenta [nTPM]":"1.1","Tissue RNA - pons [nTPM]":"7.4","Tissue RNA - prostate [nTPM]":"3.0","Tissue RNA - rectum [nTPM]":"1.2","Tissue RNA - retina [nTPM]":"9.3","Tissue RNA - salivary gland [nTPM]":"3.7","Tissue RNA - seminal vesicle [nTPM]":"4.0","Tissue RNA - skeletal muscle [nTPM]":"2.2","Tissue RNA - skin 1 [nTPM]":"2.5","Tissue RNA - small intestine [nTPM]":"2.5","Tissue RNA - smooth muscle [nTPM]":"3.9","Tissue RNA - spinal cord [nTPM]":"5.7","Tissue RNA - spleen [nTPM]":"1.3","Tissue RNA - stomach 1 [nTPM]":"2.8","Tissue RNA - testis [nTPM]":"6.9","Tissue RNA - thalamus [nTPM]":"6.5","Tissue RNA - thymus [nTPM]":"1.4","Tissue RNA - thyroid gland [nTPM]":"4.3","Tissue RNA - tongue [nTPM]":"3.5","Tissue RNA - tonsil [nTPM]":"1.9","Tissue RNA - urinary bladder [nTPM]":"5.3","Tissue RNA - vagina [nTPM]":"5.1","Tissue RNA - white matter [nTPM]":"6.4","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"5.4","Cell RNA - AN3-CA [nTPM]":"1.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"1.8","Cell RNA - BJ [nTPM]":"1.6","Cell RNA - BJ hTERT+ [nTPM]":"2.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.5","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"2.5","Cell RNA - HaCaT [nTPM]":"2.5","Cell RNA - HAP1 [nTPM]":"11.3","Cell RNA - HBEC3-KT [nTPM]":"6.0","Cell RNA - HBF TERT88 [nTPM]":"1.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"8.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"2.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.7","Cell RNA - HMC-1 [nTPM]":"0.8","Cell RNA - HSkMC [nTPM]":"0.9","Cell RNA - hTCEpi [nTPM]":"4.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"3.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.8","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"2.7","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"8.1","Cell RNA - OE19 [nTPM]":"5.5","Cell RNA - PC-3 [nTPM]":"1.8","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"7.4","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"33.7","Cell RNA - SCLC-21H [nTPM]":"6.4","Cell RNA - SH-SY5Y [nTPM]":"6.2","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.5","Cell RNA - SuSa [nTPM]":"12.2","Cell RNA - T-47d [nTPM]":"0.5","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"2.4","Cell RNA - U-2197 [nTPM]":"4.0","Cell RNA - U-251 MG [nTPM]":"7.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"3.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"6.9","Brain RNA - basal ganglia [nTPM]":"7.1","Brain RNA - cerebellum [nTPM]":"6.4","Brain RNA - cerebral cortex [nTPM]":"10.0","Brain RNA - hippocampal formation [nTPM]":"7.4","Brain RNA - hypothalamus [nTPM]":"6.7","Brain RNA - medulla oblongata [nTPM]":"6.4","Brain RNA - midbrain [nTPM]":"6.8","Brain RNA - pons [nTPM]":"7.4","Brain RNA - spinal cord [nTPM]":"5.7","Brain RNA - thalamus [nTPM]":"6.5","Brain RNA - white matter [nTPM]":"6.4","Single Cell Type RNA - Adipocytes [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"73.8","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Bipolar cells [nTPM]":"28.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"21.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"4.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.6","Single Cell Type RNA - Early spermatids [nTPM]":"7.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.4","Single Cell Type RNA - Endothelial cells [nTPM]":"3.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"171.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.3","Single Cell Type RNA - Fibroblasts [nTPM]":"6.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"35.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"13.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"170.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1.5","Single Cell Type RNA - Late spermatids [nTPM]":"3.6","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"12.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"167.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"45.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.5","Single Cell Type RNA - Spermatocytes [nTPM]":"17.4","Single Cell Type RNA - Spermatogonia [nTPM]":"5.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"1.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.9","Single Cell Type RNA - Urothelial cells [nTPM]":"4.8"},{"Gene":"MARK3","Gene synonym":["CTAK1","KP78","PAR-1A"],"Ensembl":"ENSG00000075413","Gene description":"Microtubule affinity regulating kinase 3","Uniprot":["P27448"],"Chromosome":"14","Position":"103385377-103503831","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"32","RNA blood cell specific nTPM":{"eosinophil":"101.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"32","RNA blood lineage specific nTPM":{"granulocytes":"101.5"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024652"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA024652":"AB_1853582"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.14e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Tissue RNA - adipose tissue [nTPM]":"34.6","Tissue RNA - adrenal gland [nTPM]":"52.5","Tissue RNA - amygdala [nTPM]":"14.9","Tissue RNA - appendix [nTPM]":"23.0","Tissue RNA - basal ganglia [nTPM]":"15.9","Tissue RNA - bone marrow [nTPM]":"53.2","Tissue RNA - breast [nTPM]":"27.5","Tissue RNA - cerebellum [nTPM]":"16.0","Tissue RNA - cerebral cortex [nTPM]":"22.1","Tissue RNA - cervix [nTPM]":"29.8","Tissue RNA - choroid plexus [nTPM]":"15.1","Tissue RNA - colon [nTPM]":"34.8","Tissue RNA - duodenum [nTPM]":"20.4","Tissue RNA - endometrium 1 [nTPM]":"31.3","Tissue RNA - epididymis [nTPM]":"26.7","Tissue RNA - esophagus [nTPM]":"39.8","Tissue RNA - fallopian tube [nTPM]":"36.8","Tissue RNA - gallbladder [nTPM]":"20.8","Tissue RNA - heart muscle [nTPM]":"71.5","Tissue RNA - hippocampal formation [nTPM]":"14.5","Tissue RNA - hypothalamus [nTPM]":"14.8","Tissue RNA - kidney [nTPM]":"38.7","Tissue RNA - liver [nTPM]":"30.8","Tissue RNA - lung [nTPM]":"38.3","Tissue RNA - lymph node [nTPM]":"24.9","Tissue RNA - medulla oblongata [nTPM]":"15.1","Tissue RNA - midbrain [nTPM]":"15.0","Tissue RNA - ovary [nTPM]":"33.7","Tissue RNA - pancreas [nTPM]":"46.7","Tissue RNA - parathyroid gland [nTPM]":"33.8","Tissue RNA - pituitary gland [nTPM]":"32.0","Tissue RNA - placenta [nTPM]":"22.8","Tissue RNA - pons [nTPM]":"16.2","Tissue RNA - prostate [nTPM]":"30.5","Tissue RNA - rectum [nTPM]":"21.3","Tissue RNA - retina [nTPM]":"23.2","Tissue RNA - salivary gland [nTPM]":"29.2","Tissue RNA - seminal vesicle [nTPM]":"24.2","Tissue RNA - skeletal muscle [nTPM]":"71.0","Tissue RNA - skin 1 [nTPM]":"27.3","Tissue RNA - small intestine [nTPM]":"31.8","Tissue RNA - smooth muscle [nTPM]":"30.8","Tissue RNA - spinal cord [nTPM]":"15.0","Tissue RNA - spleen [nTPM]":"42.6","Tissue RNA - stomach 1 [nTPM]":"46.5","Tissue RNA - testis [nTPM]":"38.4","Tissue RNA - thalamus [nTPM]":"14.7","Tissue RNA - thymus [nTPM]":"31.0","Tissue RNA - thyroid gland [nTPM]":"33.2","Tissue RNA - tongue [nTPM]":"42.7","Tissue RNA - tonsil [nTPM]":"26.2","Tissue RNA - urinary bladder [nTPM]":"32.1","Tissue RNA - vagina [nTPM]":"28.5","Tissue RNA - white matter [nTPM]":"15.6","Cell RNA - A-431 [nTPM]":"28.1","Cell RNA - A549 [nTPM]":"33.3","Cell RNA - AF22 [nTPM]":"52.8","Cell RNA - AN3-CA [nTPM]":"34.7","Cell RNA - ASC diff [nTPM]":"64.3","Cell RNA - ASC TERT1 [nTPM]":"43.6","Cell RNA - BEWO [nTPM]":"40.9","Cell RNA - BJ [nTPM]":"54.9","Cell RNA - BJ hTERT+ [nTPM]":"56.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"66.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"62.4","Cell RNA - CACO-2 [nTPM]":"23.3","Cell RNA - CAPAN-2 [nTPM]":"46.2","Cell RNA - Daudi [nTPM]":"36.3","Cell RNA - EFO-21 [nTPM]":"31.9","Cell RNA - fHDF\/TERT166 [nTPM]":"52.5","Cell RNA - GAMG [nTPM]":"27.0","Cell RNA - HaCaT [nTPM]":"51.5","Cell RNA - HAP1 [nTPM]":"58.3","Cell RNA - HBEC3-KT [nTPM]":"56.6","Cell RNA - HBF TERT88 [nTPM]":"81.2","Cell RNA - HDLM-2 [nTPM]":"39.4","Cell RNA - HEK 293 [nTPM]":"28.0","Cell RNA - HEL [nTPM]":"46.8","Cell RNA - HeLa [nTPM]":"34.9","Cell RNA - Hep G2 [nTPM]":"30.8","Cell RNA - HHSteC [nTPM]":"123.5","Cell RNA - HL-60 [nTPM]":"53.4","Cell RNA - HMC-1 [nTPM]":"27.2","Cell RNA - HSkMC [nTPM]":"56.1","Cell RNA - hTCEpi [nTPM]":"51.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"53.1","Cell RNA - hTERT-HME1 [nTPM]":"105.0","Cell RNA - hTERT-RPE1 [nTPM]":"51.9","Cell RNA - HUVEC TERT2 [nTPM]":"61.0","Cell RNA - JURKAT [nTPM]":"33.0","Cell RNA - K-562 [nTPM]":"45.4","Cell RNA - Karpas-707 [nTPM]":"77.1","Cell RNA - LHCN-M2 [nTPM]":"51.2","Cell RNA - MCF7 [nTPM]":"61.6","Cell RNA - MOLT-4 [nTPM]":"34.9","Cell RNA - NB-4 [nTPM]":"38.4","Cell RNA - NTERA-2 [nTPM]":"42.0","Cell RNA - OE19 [nTPM]":"57.7","Cell RNA - PC-3 [nTPM]":"56.0","Cell RNA - REH [nTPM]":"44.9","Cell RNA - RH-30 [nTPM]":"56.2","Cell RNA - RPMI-8226 [nTPM]":"30.1","Cell RNA - RPTEC TERT1 [nTPM]":"54.1","Cell RNA - RT4 [nTPM]":"52.3","Cell RNA - SCLC-21H [nTPM]":"44.5","Cell RNA - SH-SY5Y [nTPM]":"43.1","Cell RNA - SiHa [nTPM]":"59.0","Cell RNA - SK-BR-3 [nTPM]":"36.6","Cell RNA - SK-MEL-30 [nTPM]":"52.1","Cell RNA - SuSa [nTPM]":"58.7","Cell RNA - T-47d [nTPM]":"50.8","Cell RNA - THP-1 [nTPM]":"47.1","Cell RNA - TIME [nTPM]":"50.2","Cell RNA - U-138 MG [nTPM]":"34.8","Cell RNA - U-2 OS [nTPM]":"23.4","Cell RNA - U-2197 [nTPM]":"62.1","Cell RNA - U-251 MG [nTPM]":"48.4","Cell RNA - U-266\/70 [nTPM]":"44.4","Cell RNA - U-266\/84 [nTPM]":"67.0","Cell RNA - U-698 [nTPM]":"42.1","Cell RNA - U-87 MG [nTPM]":"41.5","Cell RNA - U-937 [nTPM]":"40.8","Cell RNA - WM-115 [nTPM]":"48.0","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"1.5","Blood RNA - eosinophil [nTPM]":"101.5","Blood RNA - gdT-cell [nTPM]":"1.4","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"0.9","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"2.2","Blood RNA - memory CD8 T-cell [nTPM]":"2.8","Blood RNA - myeloid DC [nTPM]":"1.8","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"2.4","Blood RNA - naive CD8 T-cell [nTPM]":"1.6","Blood RNA - neutrophil [nTPM]":"2.3","Blood RNA - NK-cell [nTPM]":"1.4","Blood RNA - non-classical monocyte [nTPM]":"1.1","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"3.1","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"14.9","Brain RNA - basal ganglia [nTPM]":"15.9","Brain RNA - cerebellum [nTPM]":"16.0","Brain RNA - cerebral cortex [nTPM]":"22.1","Brain RNA - hippocampal formation [nTPM]":"14.5","Brain RNA - hypothalamus [nTPM]":"14.8","Brain RNA - medulla oblongata [nTPM]":"15.1","Brain RNA - midbrain [nTPM]":"15.0","Brain RNA - pons [nTPM]":"16.2","Brain RNA - spinal cord [nTPM]":"15.0","Brain RNA - thalamus [nTPM]":"14.7","Brain RNA - white matter [nTPM]":"15.6","Single Cell Type RNA - Adipocytes [nTPM]":"38.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"57.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"79.1","Single Cell Type RNA - Astrocytes [nTPM]":"154.1","Single Cell Type RNA - B-cells [nTPM]":"43.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"44.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"57.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"28.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"33.0","Single Cell Type RNA - Bipolar cells [nTPM]":"78.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"74.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"47.1","Single Cell Type RNA - Club cells [nTPM]":"45.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"162.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"33.3","Single Cell Type RNA - dendritic cells [nTPM]":"47.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"36.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"46.8","Single Cell Type RNA - Early spermatids [nTPM]":"38.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"47.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"63.7","Single Cell Type RNA - Endothelial cells [nTPM]":"50.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"31.2","Single Cell Type RNA - Erythroid cells [nTPM]":"187.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"153.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"42.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"31.0","Single Cell Type RNA - Fibroblasts [nTPM]":"47.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"52.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"62.1","Single Cell Type RNA - granulocytes [nTPM]":"48.2","Single Cell Type RNA - Granulosa cells [nTPM]":"128.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"63.9","Single Cell Type RNA - Hepatocytes [nTPM]":"30.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.2","Single Cell Type RNA - Horizontal cells [nTPM]":"58.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"145.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"32.3","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"40.4","Single Cell Type RNA - Langerhans cells [nTPM]":"63.0","Single Cell Type RNA - Late spermatids [nTPM]":"52.4","Single Cell Type RNA - Leydig cells [nTPM]":"60.9","Single Cell Type RNA - Macrophages [nTPM]":"42.6","Single Cell Type RNA - Melanocytes [nTPM]":"37.4","Single Cell Type RNA - Microglial cells [nTPM]":"70.3","Single Cell Type RNA - monocytes [nTPM]":"57.5","Single Cell Type RNA - Muller glia cells [nTPM]":"34.4","Single Cell Type RNA - NK-cells [nTPM]":"61.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"138.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"172.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"60.4","Single Cell Type RNA - Paneth cells [nTPM]":"34.0","Single Cell Type RNA - Peritubular cells [nTPM]":"59.0","Single Cell Type RNA - Plasma cells [nTPM]":"55.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"67.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"34.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"36.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"86.7","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"38.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"44.1","Single Cell Type RNA - Spermatocytes [nTPM]":"74.6","Single Cell Type RNA - Spermatogonia [nTPM]":"72.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"36.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"52.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"49.1","Single Cell Type RNA - T-cells [nTPM]":"54.8","Single Cell Type RNA - Theca cells [nTPM]":"98.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"33.7","Single Cell Type RNA - Urothelial cells [nTPM]":"114.6"},{"Gene":"MARS1","Gene synonym":["CMT2U","MARS","MetRS","SPG70"],"Ensembl":"ENSG00000166986","Gene description":"Methionyl-tRNA synthetase 1","Uniprot":["P56192"],"Chromosome":"12","Position":"57475445-57517569","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase","RNA-binding","tRNA-binding"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"11.9","Cytotrophoblasts":"29.5","Extravillous trophoblasts":"22.0","Hofbauer cells":"19.3","Syncytiotrophoblasts":"38.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RH-30":"738.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004125","CAB017097"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"23000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB017097":null,"HPA004125":"AB_1079312"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.73e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.55e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.59e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Tissue RNA - adipose tissue [nTPM]":"35.9","Tissue RNA - adrenal gland [nTPM]":"47.2","Tissue RNA - amygdala [nTPM]":"63.1","Tissue RNA - appendix [nTPM]":"35.9","Tissue RNA - basal ganglia [nTPM]":"65.2","Tissue RNA - bone marrow [nTPM]":"31.6","Tissue RNA - breast [nTPM]":"31.5","Tissue RNA - cerebellum [nTPM]":"62.0","Tissue RNA - cerebral cortex [nTPM]":"83.6","Tissue RNA - cervix [nTPM]":"30.8","Tissue RNA - choroid plexus [nTPM]":"61.6","Tissue RNA - colon [nTPM]":"47.6","Tissue RNA - duodenum [nTPM]":"21.5","Tissue RNA - endometrium 1 [nTPM]":"40.7","Tissue RNA - epididymis [nTPM]":"39.0","Tissue RNA - esophagus [nTPM]":"54.3","Tissue RNA - fallopian tube [nTPM]":"30.1","Tissue RNA - gallbladder [nTPM]":"19.3","Tissue RNA - heart muscle [nTPM]":"50.5","Tissue RNA - hippocampal formation [nTPM]":"67.5","Tissue RNA - hypothalamus [nTPM]":"67.5","Tissue RNA - kidney [nTPM]":"55.7","Tissue RNA - liver [nTPM]":"60.6","Tissue RNA - lung [nTPM]":"42.7","Tissue RNA - lymph node [nTPM]":"34.5","Tissue RNA - medulla oblongata [nTPM]":"64.2","Tissue RNA - midbrain [nTPM]":"65.5","Tissue RNA - ovary [nTPM]":"24.2","Tissue RNA - pancreas [nTPM]":"64.4","Tissue RNA - parathyroid gland [nTPM]":"40.7","Tissue RNA - pituitary gland [nTPM]":"58.9","Tissue RNA - placenta [nTPM]":"27.3","Tissue RNA - pons [nTPM]":"68.1","Tissue RNA - prostate [nTPM]":"38.7","Tissue RNA - rectum [nTPM]":"29.6","Tissue RNA - retina [nTPM]":"39.6","Tissue RNA - salivary gland [nTPM]":"39.6","Tissue RNA - seminal vesicle [nTPM]":"34.0","Tissue RNA - skeletal muscle [nTPM]":"48.5","Tissue RNA - skin 1 [nTPM]":"33.0","Tissue RNA - small intestine [nTPM]":"37.3","Tissue RNA - smooth muscle [nTPM]":"41.3","Tissue RNA - spinal cord [nTPM]":"63.5","Tissue RNA - spleen [nTPM]":"53.9","Tissue RNA - stomach 1 [nTPM]":"53.2","Tissue RNA - testis [nTPM]":"50.7","Tissue RNA - thalamus [nTPM]":"65.6","Tissue RNA - thymus [nTPM]":"32.6","Tissue RNA - thyroid gland [nTPM]":"40.0","Tissue RNA - tongue [nTPM]":"33.1","Tissue RNA - tonsil [nTPM]":"44.4","Tissue RNA - urinary bladder [nTPM]":"44.8","Tissue RNA - vagina [nTPM]":"33.6","Tissue RNA - white matter [nTPM]":"67.9","Cell RNA - A-431 [nTPM]":"110.6","Cell RNA - A549 [nTPM]":"149.6","Cell RNA - AF22 [nTPM]":"99.7","Cell RNA - AN3-CA [nTPM]":"171.9","Cell RNA - ASC diff [nTPM]":"107.1","Cell RNA - ASC TERT1 [nTPM]":"64.6","Cell RNA - BEWO [nTPM]":"180.2","Cell RNA - BJ [nTPM]":"149.0","Cell RNA - BJ hTERT+ [nTPM]":"178.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"158.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"168.6","Cell RNA - CACO-2 [nTPM]":"162.9","Cell RNA - CAPAN-2 [nTPM]":"119.0","Cell RNA - Daudi [nTPM]":"192.3","Cell RNA - EFO-21 [nTPM]":"97.6","Cell RNA - fHDF\/TERT166 [nTPM]":"187.2","Cell RNA - GAMG [nTPM]":"98.3","Cell RNA - HaCaT [nTPM]":"119.4","Cell RNA - HAP1 [nTPM]":"226.0","Cell RNA - HBEC3-KT [nTPM]":"196.4","Cell RNA - HBF TERT88 [nTPM]":"166.2","Cell RNA - HDLM-2 [nTPM]":"167.4","Cell RNA - HEK 293 [nTPM]":"96.9","Cell RNA - HEL [nTPM]":"136.7","Cell RNA - HeLa [nTPM]":"52.8","Cell RNA - Hep G2 [nTPM]":"89.4","Cell RNA - HHSteC [nTPM]":"238.1","Cell RNA - HL-60 [nTPM]":"207.7","Cell RNA - HMC-1 [nTPM]":"147.5","Cell RNA - HSkMC [nTPM]":"96.2","Cell RNA - hTCEpi [nTPM]":"302.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"181.5","Cell RNA - hTERT-HME1 [nTPM]":"467.5","Cell RNA - hTERT-RPE1 [nTPM]":"76.6","Cell RNA - HUVEC TERT2 [nTPM]":"114.8","Cell RNA - JURKAT [nTPM]":"238.1","Cell RNA - K-562 [nTPM]":"212.9","Cell RNA - Karpas-707 [nTPM]":"400.3","Cell RNA - LHCN-M2 [nTPM]":"112.1","Cell RNA - MCF7 [nTPM]":"150.4","Cell RNA - MOLT-4 [nTPM]":"187.9","Cell RNA - NB-4 [nTPM]":"148.1","Cell RNA - NTERA-2 [nTPM]":"184.8","Cell RNA - OE19 [nTPM]":"173.0","Cell RNA - PC-3 [nTPM]":"162.3","Cell RNA - REH [nTPM]":"155.5","Cell RNA - RH-30 [nTPM]":"738.3","Cell RNA - RPMI-8226 [nTPM]":"200.0","Cell RNA - RPTEC TERT1 [nTPM]":"117.0","Cell RNA - RT4 [nTPM]":"86.4","Cell RNA - SCLC-21H [nTPM]":"131.6","Cell RNA - SH-SY5Y [nTPM]":"134.0","Cell RNA - SiHa [nTPM]":"79.8","Cell RNA - SK-BR-3 [nTPM]":"120.9","Cell RNA - SK-MEL-30 [nTPM]":"215.8","Cell RNA - SuSa [nTPM]":"109.6","Cell RNA - T-47d [nTPM]":"161.0","Cell RNA - THP-1 [nTPM]":"260.7","Cell RNA - TIME [nTPM]":"86.9","Cell RNA - U-138 MG [nTPM]":"57.5","Cell RNA - U-2 OS [nTPM]":"162.8","Cell RNA - U-2197 [nTPM]":"82.8","Cell RNA - U-251 MG [nTPM]":"91.6","Cell RNA - U-266\/70 [nTPM]":"357.5","Cell RNA - U-266\/84 [nTPM]":"395.8","Cell RNA - U-698 [nTPM]":"232.5","Cell RNA - U-87 MG [nTPM]":"139.7","Cell RNA - U-937 [nTPM]":"154.8","Cell RNA - WM-115 [nTPM]":"199.1","Blood RNA - basophil [nTPM]":"29.9","Blood RNA - classical monocyte [nTPM]":"29.8","Blood RNA - eosinophil [nTPM]":"39.3","Blood RNA - gdT-cell [nTPM]":"35.1","Blood RNA - intermediate monocyte [nTPM]":"53.6","Blood RNA - MAIT T-cell [nTPM]":"31.7","Blood RNA - memory B-cell [nTPM]":"24.4","Blood RNA - memory CD4 T-cell [nTPM]":"23.4","Blood RNA - memory CD8 T-cell [nTPM]":"32.0","Blood RNA - myeloid DC [nTPM]":"57.9","Blood RNA - naive B-cell [nTPM]":"14.7","Blood RNA - naive CD4 T-cell [nTPM]":"20.0","Blood RNA - naive CD8 T-cell [nTPM]":"27.4","Blood RNA - neutrophil [nTPM]":"14.5","Blood RNA - NK-cell [nTPM]":"30.0","Blood RNA - non-classical monocyte [nTPM]":"45.6","Blood RNA - plasmacytoid DC [nTPM]":"55.9","Blood RNA - T-reg [nTPM]":"26.3","Blood RNA - total PBMC [nTPM]":"34.2","Brain RNA - amygdala [nTPM]":"63.1","Brain RNA - basal ganglia [nTPM]":"65.2","Brain RNA - cerebellum [nTPM]":"62.0","Brain RNA - cerebral cortex [nTPM]":"83.6","Brain RNA - hippocampal formation [nTPM]":"67.5","Brain RNA - hypothalamus [nTPM]":"67.5","Brain RNA - medulla oblongata [nTPM]":"64.2","Brain RNA - midbrain [nTPM]":"65.5","Brain RNA - pons [nTPM]":"68.1","Brain RNA - spinal cord [nTPM]":"63.5","Brain RNA - thalamus [nTPM]":"65.6","Brain RNA - white matter [nTPM]":"67.9","Single Cell Type RNA - Adipocytes [nTPM]":"5.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"29.5","Single Cell Type RNA - dendritic cells [nTPM]":"7.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"2.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"22.0","Single Cell Type RNA - Fibroblasts [nTPM]":"4.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"3.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"38.0","Single Cell Type RNA - T-cells [nTPM]":"1.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"MARS2","Gene synonym":["mtMetRS","SPAX3"],"Ensembl":"ENSG00000247626","Gene description":"Methionyl-tRNA synthetase 2, mitochondrial","Uniprot":["Q96GW9"],"Chromosome":"2","Position":"197705369-197708395","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Deafness","Disease variant","Neurodegeneration","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"17.1","Suprabasal keratinocytes":"18.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035589","HPA035590"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 28: Keratinocytes - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035589":"AB_10601870","HPA035590":"AB_2674693"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.50e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.12e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.14e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.74e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.0","Tissue RNA - adrenal gland [nTPM]":"4.7","Tissue RNA - amygdala [nTPM]":"1.8","Tissue RNA - appendix [nTPM]":"4.7","Tissue RNA - basal ganglia [nTPM]":"2.9","Tissue RNA - bone marrow [nTPM]":"3.6","Tissue RNA - breast [nTPM]":"4.1","Tissue RNA - cerebellum [nTPM]":"3.0","Tissue RNA - cerebral cortex [nTPM]":"3.0","Tissue RNA - cervix [nTPM]":"1.8","Tissue RNA - choroid plexus [nTPM]":"1.4","Tissue RNA - colon [nTPM]":"5.4","Tissue RNA - duodenum [nTPM]":"4.7","Tissue RNA - endometrium 1 [nTPM]":"1.9","Tissue RNA - epididymis [nTPM]":"1.4","Tissue RNA - esophagus [nTPM]":"4.9","Tissue RNA - fallopian tube [nTPM]":"2.3","Tissue RNA - gallbladder [nTPM]":"2.2","Tissue RNA - heart muscle [nTPM]":"4.1","Tissue RNA - hippocampal formation [nTPM]":"2.1","Tissue RNA - hypothalamus [nTPM]":"2.5","Tissue RNA - kidney [nTPM]":"4.0","Tissue RNA - liver [nTPM]":"5.7","Tissue RNA - lung [nTPM]":"2.0","Tissue RNA - lymph node [nTPM]":"6.5","Tissue RNA - medulla oblongata [nTPM]":"2.7","Tissue RNA - midbrain [nTPM]":"2.7","Tissue RNA - ovary [nTPM]":"1.6","Tissue RNA - pancreas [nTPM]":"5.3","Tissue RNA - parathyroid gland [nTPM]":"4.1","Tissue RNA - pituitary gland [nTPM]":"0.9","Tissue RNA - placenta [nTPM]":"2.5","Tissue RNA - pons [nTPM]":"3.2","Tissue RNA - prostate [nTPM]":"2.0","Tissue RNA - rectum [nTPM]":"5.0","Tissue RNA - retina [nTPM]":"1.7","Tissue RNA - salivary gland [nTPM]":"3.1","Tissue RNA - seminal vesicle [nTPM]":"1.7","Tissue RNA - skeletal muscle [nTPM]":"4.8","Tissue RNA - skin 1 [nTPM]":"3.2","Tissue RNA - small intestine [nTPM]":"3.7","Tissue RNA - smooth muscle [nTPM]":"2.5","Tissue RNA - spinal cord [nTPM]":"2.5","Tissue RNA - spleen [nTPM]":"4.5","Tissue RNA - stomach 1 [nTPM]":"3.3","Tissue RNA - testis [nTPM]":"1.9","Tissue RNA - thalamus [nTPM]":"2.7","Tissue RNA - thymus [nTPM]":"3.2","Tissue RNA - thyroid gland [nTPM]":"3.1","Tissue RNA - tongue [nTPM]":"6.0","Tissue RNA - tonsil [nTPM]":"6.6","Tissue RNA - urinary bladder [nTPM]":"4.2","Tissue RNA - vagina [nTPM]":"2.2","Tissue RNA - white matter [nTPM]":"4.1","Cell RNA - A-431 [nTPM]":"6.9","Cell RNA - A549 [nTPM]":"8.2","Cell RNA - AF22 [nTPM]":"7.7","Cell RNA - AN3-CA [nTPM]":"13.0","Cell RNA - ASC diff [nTPM]":"7.2","Cell RNA - ASC TERT1 [nTPM]":"3.5","Cell RNA - BEWO [nTPM]":"14.5","Cell RNA - BJ [nTPM]":"5.2","Cell RNA - BJ hTERT+ [nTPM]":"4.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.3","Cell RNA - CACO-2 [nTPM]":"21.1","Cell RNA - CAPAN-2 [nTPM]":"6.3","Cell RNA - Daudi [nTPM]":"43.4","Cell RNA - EFO-21 [nTPM]":"7.6","Cell RNA - fHDF\/TERT166 [nTPM]":"3.0","Cell RNA - GAMG [nTPM]":"5.2","Cell RNA - HaCaT [nTPM]":"12.8","Cell RNA - HAP1 [nTPM]":"27.2","Cell RNA - HBEC3-KT [nTPM]":"11.2","Cell RNA - HBF TERT88 [nTPM]":"10.3","Cell RNA - HDLM-2 [nTPM]":"11.8","Cell RNA - HEK 293 [nTPM]":"15.9","Cell RNA - HEL [nTPM]":"26.7","Cell RNA - HeLa [nTPM]":"9.7","Cell RNA - Hep G2 [nTPM]":"18.7","Cell RNA - HHSteC [nTPM]":"6.8","Cell RNA - HL-60 [nTPM]":"39.7","Cell RNA - HMC-1 [nTPM]":"12.3","Cell RNA - HSkMC [nTPM]":"3.7","Cell RNA - hTCEpi [nTPM]":"14.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.6","Cell RNA - hTERT-HME1 [nTPM]":"11.3","Cell RNA - hTERT-RPE1 [nTPM]":"2.6","Cell RNA - HUVEC TERT2 [nTPM]":"6.5","Cell RNA - JURKAT [nTPM]":"12.6","Cell RNA - K-562 [nTPM]":"31.7","Cell RNA - Karpas-707 [nTPM]":"15.1","Cell RNA - LHCN-M2 [nTPM]":"5.6","Cell RNA - MCF7 [nTPM]":"11.7","Cell RNA - MOLT-4 [nTPM]":"20.3","Cell RNA - NB-4 [nTPM]":"18.7","Cell RNA - NTERA-2 [nTPM]":"13.3","Cell RNA - OE19 [nTPM]":"16.1","Cell RNA - PC-3 [nTPM]":"20.6","Cell RNA - REH [nTPM]":"20.7","Cell RNA - RH-30 [nTPM]":"8.1","Cell RNA - RPMI-8226 [nTPM]":"30.7","Cell RNA - RPTEC TERT1 [nTPM]":"11.8","Cell RNA - RT4 [nTPM]":"12.2","Cell RNA - SCLC-21H [nTPM]":"13.6","Cell RNA - SH-SY5Y [nTPM]":"6.5","Cell RNA - SiHa [nTPM]":"6.5","Cell RNA - SK-BR-3 [nTPM]":"17.5","Cell RNA - SK-MEL-30 [nTPM]":"11.9","Cell RNA - SuSa [nTPM]":"10.0","Cell RNA - T-47d [nTPM]":"7.5","Cell RNA - THP-1 [nTPM]":"13.8","Cell RNA - TIME [nTPM]":"5.2","Cell RNA - U-138 MG [nTPM]":"8.0","Cell RNA - U-2 OS [nTPM]":"6.3","Cell RNA - U-2197 [nTPM]":"6.1","Cell RNA - U-251 MG [nTPM]":"15.4","Cell RNA - U-266\/70 [nTPM]":"10.0","Cell RNA - U-266\/84 [nTPM]":"8.0","Cell RNA - U-698 [nTPM]":"35.7","Cell RNA - U-87 MG [nTPM]":"6.0","Cell RNA - U-937 [nTPM]":"23.8","Cell RNA - WM-115 [nTPM]":"7.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.5","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"4.3","Blood RNA - intermediate monocyte [nTPM]":"4.0","Blood RNA - MAIT T-cell [nTPM]":"5.0","Blood RNA - memory B-cell [nTPM]":"2.7","Blood RNA - memory CD4 T-cell [nTPM]":"3.5","Blood RNA - memory CD8 T-cell [nTPM]":"3.9","Blood RNA - myeloid DC [nTPM]":"4.0","Blood RNA - naive B-cell [nTPM]":"3.0","Blood RNA - naive CD4 T-cell [nTPM]":"5.6","Blood RNA - naive CD8 T-cell [nTPM]":"6.3","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"8.6","Blood RNA - non-classical monocyte [nTPM]":"1.9","Blood RNA - plasmacytoid DC [nTPM]":"2.8","Blood RNA - T-reg [nTPM]":"6.6","Blood RNA - total PBMC [nTPM]":"3.6","Brain RNA - amygdala [nTPM]":"1.8","Brain RNA - basal ganglia [nTPM]":"2.9","Brain RNA - cerebellum [nTPM]":"3.0","Brain RNA - cerebral cortex [nTPM]":"3.0","Brain RNA - hippocampal formation [nTPM]":"2.1","Brain RNA - hypothalamus [nTPM]":"2.5","Brain RNA - medulla oblongata [nTPM]":"2.7","Brain RNA - midbrain [nTPM]":"2.7","Brain RNA - pons [nTPM]":"3.2","Brain RNA - spinal cord [nTPM]":"2.5","Brain RNA - thalamus [nTPM]":"2.7","Brain RNA - white matter [nTPM]":"4.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"5.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"1.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.8","Single Cell Type RNA - dendritic cells [nTPM]":"2.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.1","Single Cell Type RNA - Early spermatids [nTPM]":"2.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.7","Single Cell Type RNA - Endothelial cells [nTPM]":"2.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"7.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.3","Single Cell Type RNA - Fibroblasts [nTPM]":"1.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.9","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"1.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"7.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.2","Single Cell Type RNA - Langerhans cells [nTPM]":"4.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"1.7","Single Cell Type RNA - Muller glia cells [nTPM]":"1.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.2","Single Cell Type RNA - Paneth cells [nTPM]":"2.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"2.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.1","Single Cell Type RNA - Spermatocytes [nTPM]":"3.5","Single Cell Type RNA - Spermatogonia [nTPM]":"2.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"3.9","Single Cell Type RNA - Theca cells [nTPM]":"4.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.4","Single Cell Type RNA - Urothelial cells [nTPM]":"4.8"},{"Gene":"MARVELD2","Gene synonym":["DFNB49","FLJ30532","MRVLDC2","TRIC"],"Ensembl":"ENSG00000152939","Gene description":"MARVEL domain containing 2","Uniprot":["Q8N4S9"],"Chromosome":"5","Position":"69415065-69444330","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"thyroid gland":"15.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Urothelial cells":"46.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"29.5","CAPAN-2":"24.1","HaCaT":"18.9","RT4":"21.1","SCLC-21H":"26.7","T-47d":"18.3"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"8","RNA mouse brain regional specific nTPM":{"cerebellum":"7.9"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018119","HPA061726"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA018119":"AB_2669771","HPA061726":"AB_2684595"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.84e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"0.9","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"4.0","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"2.1","Tissue RNA - choroid plexus [nTPM]":"3.2","Tissue RNA - colon [nTPM]":"5.7","Tissue RNA - duodenum [nTPM]":"7.7","Tissue RNA - endometrium 1 [nTPM]":"1.1","Tissue RNA - epididymis [nTPM]":"1.3","Tissue RNA - esophagus [nTPM]":"6.9","Tissue RNA - fallopian tube [nTPM]":"3.9","Tissue RNA - gallbladder [nTPM]":"2.9","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.5","Tissue RNA - kidney [nTPM]":"8.0","Tissue RNA - liver [nTPM]":"10.7","Tissue RNA - lung [nTPM]":"5.6","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.7","Tissue RNA - midbrain [nTPM]":"0.7","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"9.3","Tissue RNA - parathyroid gland [nTPM]":"4.6","Tissue RNA - pituitary gland [nTPM]":"2.9","Tissue RNA - placenta [nTPM]":"1.8","Tissue RNA - pons [nTPM]":"0.7","Tissue RNA - prostate [nTPM]":"3.0","Tissue RNA - rectum [nTPM]":"6.2","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"4.6","Tissue RNA - seminal vesicle [nTPM]":"2.6","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"4.3","Tissue RNA - small intestine [nTPM]":"7.7","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"0.4","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"8.1","Tissue RNA - testis [nTPM]":"1.5","Tissue RNA - thalamus [nTPM]":"0.7","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"15.7","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"1.3","Tissue RNA - urinary bladder [nTPM]":"3.0","Tissue RNA - vagina [nTPM]":"3.4","Tissue RNA - white matter [nTPM]":"0.7","Cell RNA - A-431 [nTPM]":"10.8","Cell RNA - A549 [nTPM]":"3.5","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"29.5","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.7","Cell RNA - CACO-2 [nTPM]":"14.1","Cell RNA - CAPAN-2 [nTPM]":"24.1","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"2.0","Cell RNA - fHDF\/TERT166 [nTPM]":"1.8","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"18.9","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"14.0","Cell RNA - HBF TERT88 [nTPM]":"0.5","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"5.8","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"1.1","Cell RNA - Hep G2 [nTPM]":"7.8","Cell RNA - HHSteC [nTPM]":"1.7","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.4","Cell RNA - hTCEpi [nTPM]":"15.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"1.9","Cell RNA - hTERT-RPE1 [nTPM]":"0.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.9","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"9.8","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.8","Cell RNA - OE19 [nTPM]":"6.3","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"10.0","Cell RNA - RT4 [nTPM]":"21.1","Cell RNA - SCLC-21H [nTPM]":"26.7","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"2.3","Cell RNA - SK-BR-3 [nTPM]":"2.0","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"4.3","Cell RNA - T-47d [nTPM]":"18.3","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"1.5","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"3.5","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.5","Brain RNA - medulla oblongata [nTPM]":"0.7","Brain RNA - midbrain [nTPM]":"0.7","Brain RNA - pons [nTPM]":"0.7","Brain RNA - spinal cord [nTPM]":"0.4","Brain RNA - thalamus [nTPM]":"0.7","Brain RNA - white matter [nTPM]":"0.7","Single Cell Type RNA - Adipocytes [nTPM]":"1.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"35.8","Single Cell Type RNA - Club cells [nTPM]":"23.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"22.9","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"31.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"25.1","Single Cell Type RNA - Early spermatids [nTPM]":"5.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"33.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.4","Single Cell Type RNA - Endothelial cells [nTPM]":"4.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.8","Single Cell Type RNA - Erythroid cells [nTPM]":"3.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.2","Single Cell Type RNA - Fibroblasts [nTPM]":"1.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"30.4","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"3.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"37.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.1","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.9","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"7.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"25.0","Single Cell Type RNA - Paneth cells [nTPM]":"29.7","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"25.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"33.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"38.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.5","Single Cell Type RNA - Spermatocytes [nTPM]":"4.1","Single Cell Type RNA - Spermatogonia [nTPM]":"2.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.0","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"2.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"25.6","Single Cell Type RNA - Urothelial cells [nTPM]":"46.9"},{"Gene":"MAS1","Gene synonym":[],"Ensembl":"ENSG00000130368","Gene description":"MAS1 proto-oncogene, G protein-coupled receptor","Uniprot":["P04201"],"Chromosome":"6","Position":"159890988-159917447","Protein class":["Disease related genes","G-protein coupled receptors","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"15","RNA tissue specific nTPM":{"brain":"9.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"3.2","B-cells":"2.0","Cone photoreceptor cells":"2.1","Rod photoreceptor cells":"2.1","Urothelial cells":"1.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebral cortex":"5.1","hippocampal formation":"9.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"HMC-1":"7.5"},"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"22","RNA mouse brain regional specific nTPM":{"amygdala":"38.5","basal ganglia":"26.6","cerebral cortex":"32.4","hippocampal formation":"64.6","white matter":"18.1"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"amygdala":"5.2","cerebral cortex":"8.0","hippocampal formation":"15.1"},"Antibody":["HPA079325"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA079325":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-3"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.15e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-1"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"1.7","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.7","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"5.1","Tissue RNA - cervix [nTPM]":"0.6","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"9.8","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"7.5","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.9","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.7","Brain RNA - basal ganglia [nTPM]":"0.7","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"5.1","Brain RNA - hippocampal formation [nTPM]":"9.8","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.5","Single Cell Type RNA - Muller glia cells [nTPM]":"0.7","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"1.9"},{"Gene":"MASP1","Gene synonym":["CRARF","MASP","PRSS5"],"Ensembl":"ENSG00000127241","Gene description":"Mannan binding lectin serine peptidase 1","Uniprot":["P48740"],"Chromosome":"3","Position":"187217282-187291980","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Complement activation lectin pathway","Immunity","Innate immunity"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"120.0","heart muscle":"116.1","liver":"183.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"28.1","Cardiomyocytes":"38.1","Cholangiocytes":"20.0","Endometrial stromal cells":"30.6","Fibroblasts":"16.4","Hepatic stellate cells":"23.2","Hepatocytes":"65.8"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"glioma":"6.8","liver cancer":"7.7","prostate cancer":"3.0","renal cancer":"3.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"BJ":"133.3","BJ hTERT+":"498.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001617","HPA009641"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":8670000000,"Blood concentration - Conc. blood MS [pg\/L]":"1900000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA001617":"AB_1079314","HPA009641":"AB_1079313"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.20e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.3","Tissue RNA - adrenal gland [nTPM]":"3.6","Tissue RNA - amygdala [nTPM]":"9.4","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"9.4","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"2.8","Tissue RNA - cerebellum [nTPM]":"12.9","Tissue RNA - cerebral cortex [nTPM]":"7.0","Tissue RNA - cervix [nTPM]":"120.0","Tissue RNA - choroid plexus [nTPM]":"4.9","Tissue RNA - colon [nTPM]":"57.5","Tissue RNA - duodenum [nTPM]":"1.9","Tissue RNA - endometrium 1 [nTPM]":"88.4","Tissue RNA - epididymis [nTPM]":"3.3","Tissue RNA - esophagus [nTPM]":"11.1","Tissue RNA - fallopian tube [nTPM]":"17.7","Tissue RNA - gallbladder [nTPM]":"5.1","Tissue RNA - heart muscle [nTPM]":"116.1","Tissue RNA - hippocampal formation [nTPM]":"10.4","Tissue RNA - hypothalamus [nTPM]":"27.0","Tissue RNA - kidney [nTPM]":"4.8","Tissue RNA - liver [nTPM]":"183.4","Tissue RNA - lung [nTPM]":"6.0","Tissue RNA - lymph node [nTPM]":"1.0","Tissue RNA - medulla oblongata [nTPM]":"19.2","Tissue RNA - midbrain [nTPM]":"16.5","Tissue RNA - ovary [nTPM]":"2.7","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"1.0","Tissue RNA - placenta [nTPM]":"9.0","Tissue RNA - pons [nTPM]":"15.3","Tissue RNA - prostate [nTPM]":"46.0","Tissue RNA - rectum [nTPM]":"5.6","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"2.3","Tissue RNA - seminal vesicle [nTPM]":"52.2","Tissue RNA - skeletal muscle [nTPM]":"37.5","Tissue RNA - skin 1 [nTPM]":"6.3","Tissue RNA - small intestine [nTPM]":"7.5","Tissue RNA - smooth muscle [nTPM]":"44.4","Tissue RNA - spinal cord [nTPM]":"22.2","Tissue RNA - spleen [nTPM]":"0.8","Tissue RNA - stomach 1 [nTPM]":"1.6","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"14.6","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"3.2","Tissue RNA - tongue [nTPM]":"18.9","Tissue RNA - tonsil [nTPM]":"4.3","Tissue RNA - urinary bladder [nTPM]":"9.9","Tissue RNA - vagina [nTPM]":"61.5","Tissue RNA - white matter [nTPM]":"32.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"15.7","Cell RNA - ASC TERT1 [nTPM]":"17.3","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"133.3","Cell RNA - BJ hTERT+ [nTPM]":"498.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.9","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"40.8","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.7","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.4","Cell RNA - HHSteC [nTPM]":"2.6","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"2.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.8","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"5.4","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"4.9","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.8","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.6","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"9.4","Brain RNA - basal ganglia [nTPM]":"9.4","Brain RNA - cerebellum [nTPM]":"12.9","Brain RNA - cerebral cortex [nTPM]":"7.0","Brain RNA - hippocampal formation [nTPM]":"10.4","Brain RNA - hypothalamus [nTPM]":"27.0","Brain RNA - medulla oblongata [nTPM]":"19.2","Brain RNA - midbrain [nTPM]":"16.5","Brain RNA - pons [nTPM]":"15.3","Brain RNA - spinal cord [nTPM]":"22.2","Brain RNA - thalamus [nTPM]":"14.6","Brain RNA - white matter [nTPM]":"32.0","Single Cell Type RNA - Adipocytes [nTPM]":"1.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.8","Single Cell Type RNA - Astrocytes [nTPM]":"28.1","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"38.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"30.6","Single Cell Type RNA - Endothelial cells [nTPM]":"2.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"16.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.2","Single Cell Type RNA - Hepatocytes [nTPM]":"65.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"3.7","Single Cell Type RNA - Late spermatids [nTPM]":"7.5","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"5.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"MASP2","Gene synonym":["MASP1P1"],"Ensembl":"ENSG00000009724","Gene description":"Mannan binding lectin serine peptidase 2","Uniprot":["O00187"],"Chromosome":"1","Position":"11026523-11047239","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted secreted proteins"],"Biological process":["Complement pathway","Immunity","Innate immunity"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"64","RNA tissue specific nTPM":{"liver":"476.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"52","RNA single cell type specific nTPM":{"Hepatocytes":"658.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"71","RNA cancer specific FPKM":{"liver cancer":"41.9"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"9","RNA brain regional specific nTPM":{"cerebellum":"6.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Hep G2":"16.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029313","HPA029314"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":340000000,"Blood concentration - Conc. blood MS [pg\/L]":"820000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA029313":"AB_10669654","HPA029314":"AB_10670029"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.60e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-4"},"Tissue RNA - adipose tissue [nTPM]":"2.1","Tissue RNA - adrenal gland [nTPM]":"1.2","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"1.7","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"7.4","Tissue RNA - breast [nTPM]":"2.2","Tissue RNA - cerebellum [nTPM]":"6.4","Tissue RNA - cerebral cortex [nTPM]":"0.7","Tissue RNA - cervix [nTPM]":"2.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"2.7","Tissue RNA - duodenum [nTPM]":"1.6","Tissue RNA - endometrium 1 [nTPM]":"2.8","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"1.2","Tissue RNA - fallopian tube [nTPM]":"2.7","Tissue RNA - gallbladder [nTPM]":"1.2","Tissue RNA - heart muscle [nTPM]":"1.3","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"1.0","Tissue RNA - liver [nTPM]":"476.5","Tissue RNA - lung [nTPM]":"1.8","Tissue RNA - lymph node [nTPM]":"2.7","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"2.9","Tissue RNA - pancreas [nTPM]":"2.9","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"2.3","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"1.6","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"6.9","Tissue RNA - salivary gland [nTPM]":"2.5","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"5.1","Tissue RNA - skin 1 [nTPM]":"5.3","Tissue RNA - small intestine [nTPM]":"3.4","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"2.5","Tissue RNA - stomach 1 [nTPM]":"2.4","Tissue RNA - testis [nTPM]":"1.5","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"1.9","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"2.1","Tissue RNA - vagina [nTPM]":"1.6","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"0.5","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"2.6","Cell RNA - AN3-CA [nTPM]":"1.6","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.7","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"1.2","Cell RNA - CAPAN-2 [nTPM]":"1.0","Cell RNA - Daudi [nTPM]":"2.3","Cell RNA - EFO-21 [nTPM]":"0.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"0.7","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.6","Cell RNA - HEK 293 [nTPM]":"2.3","Cell RNA - HEL [nTPM]":"1.3","Cell RNA - HeLa [nTPM]":"2.7","Cell RNA - Hep G2 [nTPM]":"16.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"2.0","Cell RNA - HMC-1 [nTPM]":"1.5","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"1.8","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"1.7","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.5","Cell RNA - MOLT-4 [nTPM]":"0.6","Cell RNA - NB-4 [nTPM]":"1.1","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.7","Cell RNA - REH [nTPM]":"1.6","Cell RNA - RH-30 [nTPM]":"0.9","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"1.3","Cell RNA - SCLC-21H [nTPM]":"1.7","Cell RNA - SH-SY5Y [nTPM]":"0.7","Cell RNA - SiHa [nTPM]":"0.9","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"1.6","Cell RNA - T-47d [nTPM]":"0.6","Cell RNA - THP-1 [nTPM]":"1.2","Cell RNA - TIME [nTPM]":"1.2","Cell RNA - U-138 MG [nTPM]":"0.9","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.8","Cell RNA - U-251 MG [nTPM]":"0.5","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"0.9","Cell RNA - U-698 [nTPM]":"1.5","Cell RNA - U-87 MG [nTPM]":"0.5","Cell RNA - U-937 [nTPM]":"1.7","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"6.4","Brain RNA - cerebral cortex [nTPM]":"0.7","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"4.6","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.2","Single Cell Type RNA - Hepatocytes [nTPM]":"658.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"12.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"MAST1","Gene synonym":["KIAA0973","SAST"],"Ensembl":"ENSG00000105613","Gene description":"Microtubule associated serine\/threonine kinase 1","Uniprot":["Q9Y2H9"],"Chromosome":"19","Position":"12833951-12874952","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"37.7","pituitary gland":"23.3","retina":"15.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"24.7","Cone photoreceptor cells":"43.8","Excitatory neurons":"64.7","Inhibitory neurons":"70.3","Oligodendrocyte precursor cells":"22.1","Rod photoreceptor cells":"20.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"3.5"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"37.7"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"1.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"T-cells":"1.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AN3-CA":"23.3","SCLC-21H":"40.5","SH-SY5Y":"20.2","U-266\/70":"16.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028181","HPA073106"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA028181":"AB_10603872","HPA073106":"AB_2732218"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"2.2","Tissue RNA - amygdala [nTPM]":"6.5","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"12.1","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"7.3","Tissue RNA - cerebral cortex [nTPM]":"37.7","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.2","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"8.3","Tissue RNA - hypothalamus [nTPM]":"2.4","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.6","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"11.2","Tissue RNA - midbrain [nTPM]":"1.1","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.6","Tissue RNA - parathyroid gland [nTPM]":"0.5","Tissue RNA - pituitary gland [nTPM]":"23.3","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"9.5","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"15.4","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"3.7","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.6","Tissue RNA - testis [nTPM]":"5.0","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"3.0","Cell RNA - A-431 [nTPM]":"3.6","Cell RNA - A549 [nTPM]":"1.6","Cell RNA - AF22 [nTPM]":"1.5","Cell RNA - AN3-CA [nTPM]":"23.3","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"1.9","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.9","Cell RNA - CACO-2 [nTPM]":"0.8","Cell RNA - CAPAN-2 [nTPM]":"1.5","Cell RNA - Daudi [nTPM]":"5.8","Cell RNA - EFO-21 [nTPM]":"2.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"3.9","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"6.8","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"4.1","Cell RNA - HEK 293 [nTPM]":"4.5","Cell RNA - HEL [nTPM]":"0.5","Cell RNA - HeLa [nTPM]":"5.8","Cell RNA - Hep G2 [nTPM]":"2.6","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"1.3","Cell RNA - HMC-1 [nTPM]":"1.2","Cell RNA - HSkMC [nTPM]":"0.5","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.8","Cell RNA - hTERT-HME1 [nTPM]":"0.7","Cell RNA - hTERT-RPE1 [nTPM]":"1.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"15.2","Cell RNA - K-562 [nTPM]":"5.2","Cell RNA - Karpas-707 [nTPM]":"3.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.8","Cell RNA - MOLT-4 [nTPM]":"2.4","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"6.9","Cell RNA - OE19 [nTPM]":"0.6","Cell RNA - PC-3 [nTPM]":"7.2","Cell RNA - REH [nTPM]":"15.9","Cell RNA - RH-30 [nTPM]":"4.6","Cell RNA - RPMI-8226 [nTPM]":"8.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.3","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"40.5","Cell RNA - SH-SY5Y [nTPM]":"20.2","Cell RNA - SiHa [nTPM]":"0.8","Cell RNA - SK-BR-3 [nTPM]":"1.4","Cell RNA - SK-MEL-30 [nTPM]":"4.3","Cell RNA - SuSa [nTPM]":"1.2","Cell RNA - T-47d [nTPM]":"3.8","Cell RNA - THP-1 [nTPM]":"2.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"2.8","Cell RNA - U-2 OS [nTPM]":"4.2","Cell RNA - U-2197 [nTPM]":"3.1","Cell RNA - U-251 MG [nTPM]":"0.8","Cell RNA - U-266\/70 [nTPM]":"16.7","Cell RNA - U-266\/84 [nTPM]":"14.5","Cell RNA - U-698 [nTPM]":"3.7","Cell RNA - U-87 MG [nTPM]":"5.1","Cell RNA - U-937 [nTPM]":"3.1","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"6.5","Brain RNA - basal ganglia [nTPM]":"12.1","Brain RNA - cerebellum [nTPM]":"7.3","Brain RNA - cerebral cortex [nTPM]":"37.7","Brain RNA - hippocampal formation [nTPM]":"8.3","Brain RNA - hypothalamus [nTPM]":"2.4","Brain RNA - medulla oblongata [nTPM]":"11.2","Brain RNA - midbrain [nTPM]":"1.1","Brain RNA - pons [nTPM]":"9.5","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"3.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.4","Single Cell Type RNA - Astrocytes [nTPM]":"7.8","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"24.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"43.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"14.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"1.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"64.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.6","Single Cell Type RNA - Fibroblasts [nTPM]":"1.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"70.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"8.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"3.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"22.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"2.5","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"20.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"8.0","Single Cell Type RNA - Spermatogonia [nTPM]":"5.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.7","Single Cell Type RNA - Urothelial cells [nTPM]":"1.2"},{"Gene":"MASTL","Gene synonym":["FLJ14813","Gwl","THC2"],"Ensembl":"ENSG00000120539","Gene description":"Microtubule associated serine\/threonine kinase like","Uniprot":["Q96GX5"],"Chromosome":"10","Position":"27154824-27187953","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Mitosis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"24.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027175","HPA054273"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA027175":"AB_1853591","HPA054273":"AB_2682433"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.52e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.81e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.71e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.0","Tissue RNA - adrenal gland [nTPM]":"3.9","Tissue RNA - amygdala [nTPM]":"1.7","Tissue RNA - appendix [nTPM]":"6.2","Tissue RNA - basal ganglia [nTPM]":"1.9","Tissue RNA - bone marrow [nTPM]":"18.7","Tissue RNA - breast [nTPM]":"5.3","Tissue RNA - cerebellum [nTPM]":"2.3","Tissue RNA - cerebral cortex [nTPM]":"2.3","Tissue RNA - cervix [nTPM]":"3.8","Tissue RNA - choroid plexus [nTPM]":"2.1","Tissue RNA - colon [nTPM]":"4.1","Tissue RNA - duodenum [nTPM]":"4.4","Tissue RNA - endometrium 1 [nTPM]":"3.9","Tissue RNA - epididymis [nTPM]":"4.5","Tissue RNA - esophagus [nTPM]":"5.9","Tissue RNA - fallopian tube [nTPM]":"3.0","Tissue RNA - gallbladder [nTPM]":"3.9","Tissue RNA - heart muscle [nTPM]":"2.5","Tissue RNA - hippocampal formation [nTPM]":"1.9","Tissue RNA - hypothalamus [nTPM]":"2.0","Tissue RNA - kidney [nTPM]":"3.9","Tissue RNA - liver [nTPM]":"4.9","Tissue RNA - lung [nTPM]":"4.0","Tissue RNA - lymph node [nTPM]":"8.9","Tissue RNA - medulla oblongata [nTPM]":"2.0","Tissue RNA - midbrain [nTPM]":"2.0","Tissue RNA - ovary [nTPM]":"3.4","Tissue RNA - pancreas [nTPM]":"3.3","Tissue RNA - parathyroid gland [nTPM]":"6.0","Tissue RNA - pituitary gland [nTPM]":"3.1","Tissue RNA - placenta [nTPM]":"6.5","Tissue RNA - pons [nTPM]":"2.1","Tissue RNA - prostate [nTPM]":"3.1","Tissue RNA - rectum [nTPM]":"5.2","Tissue RNA - retina [nTPM]":"2.7","Tissue RNA - salivary gland [nTPM]":"4.1","Tissue RNA - seminal vesicle [nTPM]":"3.0","Tissue RNA - skeletal muscle [nTPM]":"2.3","Tissue RNA - skin 1 [nTPM]":"6.0","Tissue RNA - small intestine [nTPM]":"4.3","Tissue RNA - smooth muscle [nTPM]":"4.5","Tissue RNA - spinal cord [nTPM]":"1.6","Tissue RNA - spleen [nTPM]":"4.6","Tissue RNA - stomach 1 [nTPM]":"4.7","Tissue RNA - testis [nTPM]":"6.5","Tissue RNA - thalamus [nTPM]":"2.0","Tissue RNA - thymus [nTPM]":"10.4","Tissue RNA - thyroid gland [nTPM]":"4.7","Tissue RNA - tongue [nTPM]":"2.2","Tissue RNA - tonsil [nTPM]":"7.1","Tissue RNA - urinary bladder [nTPM]":"4.5","Tissue RNA - vagina [nTPM]":"4.3","Tissue RNA - white matter [nTPM]":"2.3","Cell RNA - A-431 [nTPM]":"29.4","Cell RNA - A549 [nTPM]":"22.0","Cell RNA - AF22 [nTPM]":"43.8","Cell RNA - AN3-CA [nTPM]":"15.5","Cell RNA - ASC diff [nTPM]":"6.2","Cell RNA - ASC TERT1 [nTPM]":"9.1","Cell RNA - BEWO [nTPM]":"25.4","Cell RNA - BJ [nTPM]":"43.3","Cell RNA - BJ hTERT+ [nTPM]":"18.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"68.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"83.8","Cell RNA - CACO-2 [nTPM]":"26.7","Cell RNA - CAPAN-2 [nTPM]":"27.2","Cell RNA - Daudi [nTPM]":"22.4","Cell RNA - EFO-21 [nTPM]":"16.1","Cell RNA - fHDF\/TERT166 [nTPM]":"18.4","Cell RNA - GAMG [nTPM]":"33.5","Cell RNA - HaCaT [nTPM]":"26.8","Cell RNA - HAP1 [nTPM]":"27.9","Cell RNA - HBEC3-KT [nTPM]":"16.0","Cell RNA - HBF TERT88 [nTPM]":"48.2","Cell RNA - HDLM-2 [nTPM]":"20.2","Cell RNA - HEK 293 [nTPM]":"26.5","Cell RNA - HEL [nTPM]":"26.9","Cell RNA - HeLa [nTPM]":"14.5","Cell RNA - Hep G2 [nTPM]":"15.5","Cell RNA - HHSteC [nTPM]":"3.8","Cell RNA - HL-60 [nTPM]":"10.4","Cell RNA - HMC-1 [nTPM]":"19.8","Cell RNA - HSkMC [nTPM]":"5.6","Cell RNA - hTCEpi [nTPM]":"7.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"41.6","Cell RNA - hTERT-HME1 [nTPM]":"7.9","Cell RNA - hTERT-RPE1 [nTPM]":"9.0","Cell RNA - HUVEC TERT2 [nTPM]":"14.7","Cell RNA - JURKAT [nTPM]":"18.2","Cell RNA - K-562 [nTPM]":"21.1","Cell RNA - Karpas-707 [nTPM]":"49.9","Cell RNA - LHCN-M2 [nTPM]":"41.5","Cell RNA - MCF7 [nTPM]":"17.9","Cell RNA - MOLT-4 [nTPM]":"34.8","Cell RNA - NB-4 [nTPM]":"11.2","Cell RNA - NTERA-2 [nTPM]":"32.0","Cell RNA - OE19 [nTPM]":"15.9","Cell RNA - PC-3 [nTPM]":"8.9","Cell RNA - REH [nTPM]":"22.2","Cell RNA - RH-30 [nTPM]":"71.9","Cell RNA - RPMI-8226 [nTPM]":"18.9","Cell RNA - RPTEC TERT1 [nTPM]":"17.4","Cell RNA - RT4 [nTPM]":"10.6","Cell RNA - SCLC-21H [nTPM]":"19.2","Cell RNA - SH-SY5Y [nTPM]":"26.8","Cell RNA - SiHa [nTPM]":"26.0","Cell RNA - SK-BR-3 [nTPM]":"17.6","Cell RNA - SK-MEL-30 [nTPM]":"19.1","Cell RNA - SuSa [nTPM]":"28.1","Cell RNA - T-47d [nTPM]":"17.2","Cell RNA - THP-1 [nTPM]":"21.4","Cell RNA - TIME [nTPM]":"12.6","Cell RNA - U-138 MG [nTPM]":"17.0","Cell RNA - U-2 OS [nTPM]":"36.3","Cell RNA - U-2197 [nTPM]":"44.0","Cell RNA - U-251 MG [nTPM]":"37.4","Cell RNA - U-266\/70 [nTPM]":"5.9","Cell RNA - U-266\/84 [nTPM]":"10.3","Cell RNA - U-698 [nTPM]":"34.7","Cell RNA - U-87 MG [nTPM]":"18.3","Cell RNA - U-937 [nTPM]":"31.1","Cell RNA - WM-115 [nTPM]":"14.8","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"1.8","Blood RNA - eosinophil [nTPM]":"1.7","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"1.7","Blood RNA - MAIT T-cell [nTPM]":"1.1","Blood RNA - memory B-cell [nTPM]":"1.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"1.0","Blood RNA - naive B-cell [nTPM]":"1.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.9","Blood RNA - naive CD8 T-cell [nTPM]":"0.8","Blood RNA - neutrophil [nTPM]":"2.3","Blood RNA - NK-cell [nTPM]":"1.0","Blood RNA - non-classical monocyte [nTPM]":"1.8","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"1.6","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"1.7","Brain RNA - basal ganglia [nTPM]":"1.9","Brain RNA - cerebellum [nTPM]":"2.3","Brain RNA - cerebral cortex [nTPM]":"2.3","Brain RNA - hippocampal formation [nTPM]":"1.9","Brain RNA - hypothalamus [nTPM]":"2.0","Brain RNA - medulla oblongata [nTPM]":"2.0","Brain RNA - midbrain [nTPM]":"2.0","Brain RNA - pons [nTPM]":"2.1","Brain RNA - spinal cord [nTPM]":"1.6","Brain RNA - thalamus [nTPM]":"2.0","Brain RNA - white matter [nTPM]":"2.3","Single Cell Type RNA - Adipocytes [nTPM]":"4.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.8","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"7.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"7.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.6","Single Cell Type RNA - dendritic cells [nTPM]":"10.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"4.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.3","Single Cell Type RNA - Endothelial cells [nTPM]":"4.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"7.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"24.9","Single Cell Type RNA - Fibroblasts [nTPM]":"7.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.9","Single Cell Type RNA - granulocytes [nTPM]":"12.7","Single Cell Type RNA - Granulosa cells [nTPM]":"6.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"2.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.8","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.7","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"7.8","Single Cell Type RNA - Langerhans cells [nTPM]":"19.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.7","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"11.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"5.1","Single Cell Type RNA - Muller glia cells [nTPM]":"1.8","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.4","Single Cell Type RNA - Paneth cells [nTPM]":"2.9","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"7.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.3","Single Cell Type RNA - Spermatocytes [nTPM]":"14.9","Single Cell Type RNA - Spermatogonia [nTPM]":"14.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.2","Single Cell Type RNA - T-cells [nTPM]":"11.6","Single Cell Type RNA - Theca cells [nTPM]":"5.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.5","Single Cell Type RNA - Urothelial cells [nTPM]":"6.6"},{"Gene":"MAT1A","Gene synonym":["MAT","MATA1","SAMS","SAMS1"],"Ensembl":"ENSG00000151224","Gene description":"Methionine adenosyltransferase 1A","Uniprot":["Q00266"],"Chromosome":"10","Position":"80271820-80289658","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["One-carbon metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"23","RNA tissue specific nTPM":{"liver":"1346.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"55","RNA single cell type specific nTPM":{"Hepatocytes":"5534.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"54","RNA cancer specific FPKM":{"liver cancer":"209.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"14","RNA cell line specific nTPM":{"Hep G2":"94.9"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048627"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1900000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA048627":"AB_2680465"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-16"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.8","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.9","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"57.5","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"1.2","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.9","Tissue RNA - liver [nTPM]":"1346.5","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.6","Tissue RNA - midbrain [nTPM]":"0.8","Tissue RNA - ovary [nTPM]":"6.3","Tissue RNA - pancreas [nTPM]":"43.8","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"1.9","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"4.2","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"3.7","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.5","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"6.5","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"3.2","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"1.6","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"94.9","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"2.1","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"1.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"1.2","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.8","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.6","Brain RNA - midbrain [nTPM]":"0.8","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"8.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"67.2","Single Cell Type RNA - Club cells [nTPM]":"0.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"23.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"5.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"69.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"7.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"76.8","Single Cell Type RNA - Hepatocytes [nTPM]":"5534.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"100.4","Single Cell Type RNA - Langerhans cells [nTPM]":"0.6","Single Cell Type RNA - Late spermatids [nTPM]":"5.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"2.7","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"6.0","Single Cell Type RNA - Theca cells [nTPM]":"1.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"MBOAT7","Gene synonym":["BB1","hMBOA-7","LENG4","LPLAT"],"Ensembl":"ENSG00000125505","Gene description":"Membrane bound O-acyltransferase domain containing 7","Uniprot":["Q96N66"],"Chromosome":"19","Position":"54173412-54189882","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"108.4"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"basophil":"157.3","eosinophil":"265.9","neutrophil":"239.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"granulocytes":"265.9"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"216.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055967"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA055967":"AB_2682990"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.55e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.13e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.62e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.31e-4"},"Tissue RNA - adipose tissue [nTPM]":"14.9","Tissue RNA - adrenal gland [nTPM]":"108.4","Tissue RNA - amygdala [nTPM]":"17.6","Tissue RNA - appendix [nTPM]":"13.4","Tissue RNA - basal ganglia [nTPM]":"14.8","Tissue RNA - bone marrow [nTPM]":"13.1","Tissue RNA - breast [nTPM]":"13.7","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"21.4","Tissue RNA - cervix [nTPM]":"19.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"27.8","Tissue RNA - duodenum [nTPM]":"27.0","Tissue RNA - endometrium 1 [nTPM]":"19.0","Tissue RNA - epididymis [nTPM]":"6.6","Tissue RNA - esophagus [nTPM]":"20.6","Tissue RNA - fallopian tube [nTPM]":"20.1","Tissue RNA - gallbladder [nTPM]":"9.2","Tissue RNA - heart muscle [nTPM]":"12.8","Tissue RNA - hippocampal formation [nTPM]":"17.6","Tissue RNA - hypothalamus [nTPM]":"34.4","Tissue RNA - kidney [nTPM]":"19.2","Tissue RNA - liver [nTPM]":"16.0","Tissue RNA - lung [nTPM]":"23.6","Tissue RNA - lymph node [nTPM]":"4.8","Tissue RNA - medulla oblongata [nTPM]":"24.9","Tissue RNA - midbrain [nTPM]":"27.8","Tissue RNA - ovary [nTPM]":"23.0","Tissue RNA - pancreas [nTPM]":"21.0","Tissue RNA - parathyroid gland [nTPM]":"18.9","Tissue RNA - pituitary gland [nTPM]":"22.8","Tissue RNA - placenta [nTPM]":"6.9","Tissue RNA - pons [nTPM]":"29.2","Tissue RNA - prostate [nTPM]":"17.3","Tissue RNA - rectum [nTPM]":"5.3","Tissue RNA - retina [nTPM]":"1.0","Tissue RNA - salivary gland [nTPM]":"18.6","Tissue RNA - seminal vesicle [nTPM]":"20.2","Tissue RNA - skeletal muscle [nTPM]":"7.9","Tissue RNA - skin 1 [nTPM]":"21.1","Tissue RNA - small intestine [nTPM]":"25.3","Tissue RNA - smooth muscle [nTPM]":"4.4","Tissue RNA - spinal cord [nTPM]":"2.7","Tissue RNA - spleen [nTPM]":"26.6","Tissue RNA - stomach 1 [nTPM]":"19.9","Tissue RNA - testis [nTPM]":"36.3","Tissue RNA - thalamus [nTPM]":"28.7","Tissue RNA - thymus [nTPM]":"3.2","Tissue RNA - thyroid gland [nTPM]":"15.9","Tissue RNA - tongue [nTPM]":"1.1","Tissue RNA - tonsil [nTPM]":"2.3","Tissue RNA - urinary bladder [nTPM]":"32.5","Tissue RNA - vagina [nTPM]":"18.1","Tissue RNA - white matter [nTPM]":"4.8","Cell RNA - A-431 [nTPM]":"66.8","Cell RNA - A549 [nTPM]":"43.2","Cell RNA - AF22 [nTPM]":"3.8","Cell RNA - AN3-CA [nTPM]":"50.8","Cell RNA - ASC diff [nTPM]":"21.0","Cell RNA - ASC TERT1 [nTPM]":"15.4","Cell RNA - BEWO [nTPM]":"57.1","Cell RNA - BJ [nTPM]":"90.5","Cell RNA - BJ hTERT+ [nTPM]":"42.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"32.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"49.2","Cell RNA - CACO-2 [nTPM]":"22.1","Cell RNA - CAPAN-2 [nTPM]":"64.3","Cell RNA - Daudi [nTPM]":"11.3","Cell RNA - EFO-21 [nTPM]":"46.5","Cell RNA - fHDF\/TERT166 [nTPM]":"34.4","Cell RNA - GAMG [nTPM]":"10.9","Cell RNA - HaCaT [nTPM]":"111.9","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"26.1","Cell RNA - HBF TERT88 [nTPM]":"9.0","Cell RNA - HDLM-2 [nTPM]":"16.1","Cell RNA - HEK 293 [nTPM]":"54.6","Cell RNA - HEL [nTPM]":"12.8","Cell RNA - HeLa [nTPM]":"30.0","Cell RNA - Hep G2 [nTPM]":"12.6","Cell RNA - HHSteC [nTPM]":"18.9","Cell RNA - HL-60 [nTPM]":"29.0","Cell RNA - HMC-1 [nTPM]":"216.2","Cell RNA - HSkMC [nTPM]":"31.0","Cell RNA - hTCEpi [nTPM]":"17.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"17.3","Cell RNA - hTERT-HME1 [nTPM]":"9.8","Cell RNA - hTERT-RPE1 [nTPM]":"44.1","Cell RNA - HUVEC TERT2 [nTPM]":"46.0","Cell RNA - JURKAT [nTPM]":"11.0","Cell RNA - K-562 [nTPM]":"51.6","Cell RNA - Karpas-707 [nTPM]":"42.2","Cell RNA - LHCN-M2 [nTPM]":"9.2","Cell RNA - MCF7 [nTPM]":"32.2","Cell RNA - MOLT-4 [nTPM]":"10.9","Cell RNA - NB-4 [nTPM]":"22.7","Cell RNA - NTERA-2 [nTPM]":"22.0","Cell RNA - OE19 [nTPM]":"21.1","Cell RNA - PC-3 [nTPM]":"60.1","Cell RNA - REH [nTPM]":"28.4","Cell RNA - RH-30 [nTPM]":"7.3","Cell RNA - RPMI-8226 [nTPM]":"24.9","Cell RNA - RPTEC TERT1 [nTPM]":"47.0","Cell RNA - RT4 [nTPM]":"71.1","Cell RNA - SCLC-21H [nTPM]":"2.3","Cell RNA - SH-SY5Y [nTPM]":"14.3","Cell RNA - SiHa [nTPM]":"57.3","Cell RNA - SK-BR-3 [nTPM]":"37.0","Cell RNA - SK-MEL-30 [nTPM]":"16.3","Cell RNA - SuSa [nTPM]":"4.2","Cell RNA - T-47d [nTPM]":"34.5","Cell RNA - THP-1 [nTPM]":"2.8","Cell RNA - TIME [nTPM]":"73.1","Cell RNA - U-138 MG [nTPM]":"49.4","Cell RNA - U-2 OS [nTPM]":"16.0","Cell RNA - U-2197 [nTPM]":"12.1","Cell RNA - U-251 MG [nTPM]":"40.8","Cell RNA - U-266\/70 [nTPM]":"17.4","Cell RNA - U-266\/84 [nTPM]":"31.0","Cell RNA - U-698 [nTPM]":"6.4","Cell RNA - U-87 MG [nTPM]":"66.1","Cell RNA - U-937 [nTPM]":"25.8","Cell RNA - WM-115 [nTPM]":"27.9","Blood RNA - basophil [nTPM]":"157.3","Blood RNA - classical monocyte [nTPM]":"22.5","Blood RNA - eosinophil [nTPM]":"265.9","Blood RNA - gdT-cell [nTPM]":"2.2","Blood RNA - intermediate monocyte [nTPM]":"11.8","Blood RNA - MAIT T-cell [nTPM]":"3.3","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"3.2","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"24.8","Blood RNA - naive B-cell [nTPM]":"1.5","Blood RNA - naive CD4 T-cell [nTPM]":"1.1","Blood RNA - naive CD8 T-cell [nTPM]":"1.7","Blood RNA - neutrophil [nTPM]":"239.1","Blood RNA - NK-cell [nTPM]":"7.8","Blood RNA - non-classical monocyte [nTPM]":"7.0","Blood RNA - plasmacytoid DC [nTPM]":"7.0","Blood RNA - T-reg [nTPM]":"1.9","Blood RNA - total PBMC [nTPM]":"8.6","Brain RNA - amygdala [nTPM]":"17.6","Brain RNA - basal ganglia [nTPM]":"14.8","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"21.4","Brain RNA - hippocampal formation [nTPM]":"17.6","Brain RNA - hypothalamus [nTPM]":"34.4","Brain RNA - medulla oblongata [nTPM]":"24.9","Brain RNA - midbrain [nTPM]":"27.8","Brain RNA - pons [nTPM]":"29.2","Brain RNA - spinal cord [nTPM]":"2.7","Brain RNA - thalamus [nTPM]":"28.7","Brain RNA - white matter [nTPM]":"4.8","Single Cell Type RNA - Adipocytes [nTPM]":"11.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.4","Single Cell Type RNA - Astrocytes [nTPM]":"11.4","Single Cell Type RNA - B-cells [nTPM]":"11.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"66.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"15.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"31.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"19.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"31.5","Single Cell Type RNA - Club cells [nTPM]":"23.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"43.5","Single Cell Type RNA - dendritic cells [nTPM]":"15.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"88.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"52.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"28.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.1","Single Cell Type RNA - Endothelial cells [nTPM]":"18.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"42.5","Single Cell Type RNA - Erythroid cells [nTPM]":"13.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"33.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"52.2","Single Cell Type RNA - Fibroblasts [nTPM]":"16.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.4","Single Cell Type RNA - granulocytes [nTPM]":"76.8","Single Cell Type RNA - Granulosa cells [nTPM]":"25.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.0","Single Cell Type RNA - Hepatocytes [nTPM]":"22.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"32.2","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"49.6","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"36.8","Single Cell Type RNA - Langerhans cells [nTPM]":"38.1","Single Cell Type RNA - Late spermatids [nTPM]":"4.3","Single Cell Type RNA - Leydig cells [nTPM]":"19.3","Single Cell Type RNA - Macrophages [nTPM]":"52.5","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"48.9","Single Cell Type RNA - Muller glia cells [nTPM]":"24.6","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"28.6","Single Cell Type RNA - Paneth cells [nTPM]":"43.0","Single Cell Type RNA - Peritubular cells [nTPM]":"15.4","Single Cell Type RNA - Plasma cells [nTPM]":"9.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"44.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"101.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.5","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.6","Single Cell Type RNA - Spermatocytes [nTPM]":"5.1","Single Cell Type RNA - Spermatogonia [nTPM]":"15.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"51.6","Single Cell Type RNA - T-cells [nTPM]":"23.0","Single Cell Type RNA - Theca cells [nTPM]":"46.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"46.6","Single Cell Type RNA - Urothelial cells [nTPM]":"47.2"},{"Gene":"MBTPS1","Gene synonym":["KIAA0091","PCSK8","S1P","SKI-1"],"Ensembl":"ENSG00000140943","Gene description":"Membrane bound transcription factor peptidase, site 1","Uniprot":["Q14703"],"Chromosome":"16","Position":"84053761-84116942","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Steroid metabolism","Sterol metabolism"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"318.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056109"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA056109":"AB_2683040"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.21e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-2"},"Tissue RNA - adipose tissue [nTPM]":"45.8","Tissue RNA - adrenal gland [nTPM]":"33.7","Tissue RNA - amygdala [nTPM]":"12.7","Tissue RNA - appendix [nTPM]":"26.2","Tissue RNA - basal ganglia [nTPM]":"16.4","Tissue RNA - bone marrow [nTPM]":"24.6","Tissue RNA - breast [nTPM]":"42.8","Tissue RNA - cerebellum [nTPM]":"17.6","Tissue RNA - cerebral cortex [nTPM]":"13.3","Tissue RNA - cervix [nTPM]":"41.2","Tissue RNA - choroid plexus [nTPM]":"18.1","Tissue RNA - colon [nTPM]":"38.7","Tissue RNA - duodenum [nTPM]":"26.0","Tissue RNA - endometrium 1 [nTPM]":"40.8","Tissue RNA - epididymis [nTPM]":"25.6","Tissue RNA - esophagus [nTPM]":"28.2","Tissue RNA - fallopian tube [nTPM]":"45.6","Tissue RNA - gallbladder [nTPM]":"32.2","Tissue RNA - heart muscle [nTPM]":"44.6","Tissue RNA - hippocampal formation [nTPM]":"13.1","Tissue RNA - hypothalamus [nTPM]":"17.8","Tissue RNA - kidney [nTPM]":"36.7","Tissue RNA - liver [nTPM]":"27.5","Tissue RNA - lung [nTPM]":"35.5","Tissue RNA - lymph node [nTPM]":"27.5","Tissue RNA - medulla oblongata [nTPM]":"6.3","Tissue RNA - midbrain [nTPM]":"8.0","Tissue RNA - ovary [nTPM]":"49.4","Tissue RNA - pancreas [nTPM]":"36.4","Tissue RNA - parathyroid gland [nTPM]":"58.5","Tissue RNA - pituitary gland [nTPM]":"38.8","Tissue RNA - placenta [nTPM]":"37.1","Tissue RNA - pons [nTPM]":"8.9","Tissue RNA - prostate [nTPM]":"37.3","Tissue RNA - rectum [nTPM]":"33.7","Tissue RNA - retina [nTPM]":"108.7","Tissue RNA - salivary gland [nTPM]":"42.4","Tissue RNA - seminal vesicle [nTPM]":"40.3","Tissue RNA - skeletal muscle [nTPM]":"18.9","Tissue RNA - skin 1 [nTPM]":"27.8","Tissue RNA - small intestine [nTPM]":"26.4","Tissue RNA - smooth muscle [nTPM]":"41.2","Tissue RNA - spinal cord [nTPM]":"5.9","Tissue RNA - spleen [nTPM]":"30.1","Tissue RNA - stomach 1 [nTPM]":"30.7","Tissue RNA - testis [nTPM]":"19.6","Tissue RNA - thalamus [nTPM]":"16.5","Tissue RNA - thymus [nTPM]":"33.4","Tissue RNA - thyroid gland [nTPM]":"53.9","Tissue RNA - tongue [nTPM]":"35.6","Tissue RNA - tonsil [nTPM]":"29.9","Tissue RNA - urinary bladder [nTPM]":"35.2","Tissue RNA - vagina [nTPM]":"21.3","Tissue RNA - white matter [nTPM]":"8.6","Cell RNA - A-431 [nTPM]":"49.4","Cell RNA - A549 [nTPM]":"61.3","Cell RNA - AF22 [nTPM]":"53.8","Cell RNA - AN3-CA [nTPM]":"75.2","Cell RNA - ASC diff [nTPM]":"124.2","Cell RNA - ASC TERT1 [nTPM]":"100.1","Cell RNA - BEWO [nTPM]":"42.2","Cell RNA - BJ [nTPM]":"81.2","Cell RNA - BJ hTERT+ [nTPM]":"124.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"70.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"52.6","Cell RNA - CACO-2 [nTPM]":"43.7","Cell RNA - CAPAN-2 [nTPM]":"71.0","Cell RNA - Daudi [nTPM]":"47.0","Cell RNA - EFO-21 [nTPM]":"82.0","Cell RNA - fHDF\/TERT166 [nTPM]":"117.3","Cell RNA - GAMG [nTPM]":"55.8","Cell RNA - HaCaT [nTPM]":"52.9","Cell RNA - HAP1 [nTPM]":"50.2","Cell RNA - HBEC3-KT [nTPM]":"56.3","Cell RNA - HBF TERT88 [nTPM]":"77.9","Cell RNA - HDLM-2 [nTPM]":"42.6","Cell RNA - HEK 293 [nTPM]":"55.9","Cell RNA - HEL [nTPM]":"34.4","Cell RNA - HeLa [nTPM]":"55.8","Cell RNA - Hep G2 [nTPM]":"61.3","Cell RNA - HHSteC [nTPM]":"59.9","Cell RNA - HL-60 [nTPM]":"84.2","Cell RNA - HMC-1 [nTPM]":"72.7","Cell RNA - HSkMC [nTPM]":"103.6","Cell RNA - hTCEpi [nTPM]":"79.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"64.8","Cell RNA - hTERT-HME1 [nTPM]":"55.5","Cell RNA - hTERT-RPE1 [nTPM]":"100.3","Cell RNA - HUVEC TERT2 [nTPM]":"92.4","Cell RNA - JURKAT [nTPM]":"62.2","Cell RNA - K-562 [nTPM]":"45.6","Cell RNA - Karpas-707 [nTPM]":"40.3","Cell RNA - LHCN-M2 [nTPM]":"43.1","Cell RNA - MCF7 [nTPM]":"85.0","Cell RNA - MOLT-4 [nTPM]":"46.6","Cell RNA - NB-4 [nTPM]":"46.4","Cell RNA - NTERA-2 [nTPM]":"50.3","Cell RNA - OE19 [nTPM]":"27.7","Cell RNA - PC-3 [nTPM]":"43.2","Cell RNA - REH [nTPM]":"59.6","Cell RNA - RH-30 [nTPM]":"28.7","Cell RNA - RPMI-8226 [nTPM]":"34.1","Cell RNA - RPTEC TERT1 [nTPM]":"56.1","Cell RNA - RT4 [nTPM]":"40.2","Cell RNA - SCLC-21H [nTPM]":"41.0","Cell RNA - SH-SY5Y [nTPM]":"51.2","Cell RNA - SiHa [nTPM]":"156.9","Cell RNA - SK-BR-3 [nTPM]":"42.9","Cell RNA - SK-MEL-30 [nTPM]":"62.1","Cell RNA - SuSa [nTPM]":"58.3","Cell RNA - T-47d [nTPM]":"134.3","Cell RNA - THP-1 [nTPM]":"76.4","Cell RNA - TIME [nTPM]":"99.0","Cell RNA - U-138 MG [nTPM]":"72.3","Cell RNA - U-2 OS [nTPM]":"52.5","Cell RNA - U-2197 [nTPM]":"43.7","Cell RNA - U-251 MG [nTPM]":"38.7","Cell RNA - U-266\/70 [nTPM]":"50.5","Cell RNA - U-266\/84 [nTPM]":"102.6","Cell RNA - U-698 [nTPM]":"90.5","Cell RNA - U-87 MG [nTPM]":"52.6","Cell RNA - U-937 [nTPM]":"50.6","Cell RNA - WM-115 [nTPM]":"45.2","Blood RNA - basophil [nTPM]":"8.0","Blood RNA - classical monocyte [nTPM]":"16.3","Blood RNA - eosinophil [nTPM]":"15.0","Blood RNA - gdT-cell [nTPM]":"16.3","Blood RNA - intermediate monocyte [nTPM]":"13.8","Blood RNA - MAIT T-cell [nTPM]":"16.8","Blood RNA - memory B-cell [nTPM]":"11.3","Blood RNA - memory CD4 T-cell [nTPM]":"14.0","Blood RNA - memory CD8 T-cell [nTPM]":"15.4","Blood RNA - myeloid DC [nTPM]":"12.8","Blood RNA - naive B-cell [nTPM]":"9.6","Blood RNA - naive CD4 T-cell [nTPM]":"16.9","Blood RNA - naive CD8 T-cell [nTPM]":"15.3","Blood RNA - neutrophil [nTPM]":"4.5","Blood RNA - NK-cell [nTPM]":"17.0","Blood RNA - non-classical monocyte [nTPM]":"11.6","Blood RNA - plasmacytoid DC [nTPM]":"7.1","Blood RNA - T-reg [nTPM]":"9.6","Blood RNA - total PBMC [nTPM]":"18.3","Brain RNA - amygdala [nTPM]":"12.7","Brain RNA - basal ganglia [nTPM]":"16.4","Brain RNA - cerebellum [nTPM]":"17.6","Brain RNA - cerebral cortex [nTPM]":"13.3","Brain RNA - hippocampal formation [nTPM]":"13.1","Brain RNA - hypothalamus [nTPM]":"17.8","Brain RNA - medulla oblongata [nTPM]":"6.3","Brain RNA - midbrain [nTPM]":"8.0","Brain RNA - pons [nTPM]":"8.9","Brain RNA - spinal cord [nTPM]":"5.9","Brain RNA - thalamus [nTPM]":"16.5","Brain RNA - white matter [nTPM]":"8.6","Single Cell Type RNA - Adipocytes [nTPM]":"54.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"50.7","Single Cell Type RNA - Astrocytes [nTPM]":"27.1","Single Cell Type RNA - B-cells [nTPM]":"33.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"25.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.9","Single Cell Type RNA - Bipolar cells [nTPM]":"68.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"62.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"56.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"50.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"44.3","Single Cell Type RNA - Club cells [nTPM]":"41.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"166.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"24.4","Single Cell Type RNA - dendritic cells [nTPM]":"41.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"28.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"24.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"70.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"67.8","Single Cell Type RNA - Endothelial cells [nTPM]":"39.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"34.9","Single Cell Type RNA - Erythroid cells [nTPM]":"19.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"50.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"27.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.4","Single Cell Type RNA - Fibroblasts [nTPM]":"48.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"92.7","Single Cell Type RNA - granulocytes [nTPM]":"29.1","Single Cell Type RNA - Granulosa cells [nTPM]":"103.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"36.0","Single Cell Type RNA - Hepatocytes [nTPM]":"33.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.7","Single Cell Type RNA - Horizontal cells [nTPM]":"84.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"53.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.6","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"21.0","Single Cell Type RNA - Langerhans cells [nTPM]":"10.8","Single Cell Type RNA - Late spermatids [nTPM]":"5.5","Single Cell Type RNA - Leydig cells [nTPM]":"53.4","Single Cell Type RNA - Macrophages [nTPM]":"23.3","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"36.5","Single Cell Type RNA - monocytes [nTPM]":"22.5","Single Cell Type RNA - Muller glia cells [nTPM]":"44.4","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"57.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"39.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"30.2","Single Cell Type RNA - Paneth cells [nTPM]":"24.8","Single Cell Type RNA - Peritubular cells [nTPM]":"50.4","Single Cell Type RNA - Plasma cells [nTPM]":"59.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"56.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"318.6","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"60.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"42.2","Single Cell Type RNA - Spermatocytes [nTPM]":"12.6","Single Cell Type RNA - Spermatogonia [nTPM]":"24.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"21.6","Single Cell Type RNA - T-cells [nTPM]":"34.3","Single Cell Type RNA - Theca cells [nTPM]":"75.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"33.8","Single Cell Type RNA - Urothelial cells [nTPM]":"28.6"},{"Gene":"MBTPS2","Gene synonym":["KFSD","S2P"],"Ensembl":"ENSG00000012174","Gene description":"Membrane bound transcription factor peptidase, site 2","Uniprot":["O43462"],"Chromosome":"X","Position":"21839617-21885423","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Steroid metabolism","Sterol metabolism"],"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant","Ichthyosis","Osteogenesis imperfecta","Palmoplantar keratoderma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005494","CAB009486"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Mitochondria","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB009486":"AB_2140370","HPA005494":"AB_1079329"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.6","Tissue RNA - adrenal gland [nTPM]":"10.6","Tissue RNA - amygdala [nTPM]":"3.5","Tissue RNA - appendix [nTPM]":"5.2","Tissue RNA - basal ganglia [nTPM]":"4.0","Tissue RNA - bone marrow [nTPM]":"1.7","Tissue RNA - breast [nTPM]":"8.8","Tissue RNA - cerebellum [nTPM]":"7.8","Tissue RNA - cerebral cortex [nTPM]":"4.9","Tissue RNA - cervix [nTPM]":"7.5","Tissue RNA - choroid plexus [nTPM]":"4.5","Tissue RNA - colon [nTPM]":"5.1","Tissue RNA - duodenum [nTPM]":"5.2","Tissue RNA - endometrium 1 [nTPM]":"9.7","Tissue RNA - epididymis [nTPM]":"6.0","Tissue RNA - esophagus [nTPM]":"5.8","Tissue RNA - fallopian tube [nTPM]":"7.3","Tissue RNA - gallbladder [nTPM]":"6.7","Tissue RNA - heart muscle [nTPM]":"7.7","Tissue RNA - hippocampal formation [nTPM]":"3.7","Tissue RNA - hypothalamus [nTPM]":"4.1","Tissue RNA - kidney [nTPM]":"9.4","Tissue RNA - liver [nTPM]":"18.7","Tissue RNA - lung [nTPM]":"5.5","Tissue RNA - lymph node [nTPM]":"5.0","Tissue RNA - medulla oblongata [nTPM]":"4.4","Tissue RNA - midbrain [nTPM]":"4.1","Tissue RNA - ovary [nTPM]":"12.5","Tissue RNA - pancreas [nTPM]":"7.3","Tissue RNA - parathyroid gland [nTPM]":"11.0","Tissue RNA - pituitary gland [nTPM]":"3.8","Tissue RNA - placenta [nTPM]":"11.6","Tissue RNA - pons [nTPM]":"4.9","Tissue RNA - prostate [nTPM]":"10.5","Tissue RNA - rectum [nTPM]":"6.0","Tissue RNA - retina [nTPM]":"8.8","Tissue RNA - salivary gland [nTPM]":"6.6","Tissue RNA - seminal vesicle [nTPM]":"8.5","Tissue RNA - skeletal muscle [nTPM]":"7.1","Tissue RNA - skin 1 [nTPM]":"3.7","Tissue RNA - small intestine [nTPM]":"4.2","Tissue RNA - smooth muscle [nTPM]":"10.1","Tissue RNA - spinal cord [nTPM]":"4.1","Tissue RNA - spleen [nTPM]":"4.8","Tissue RNA - stomach 1 [nTPM]":"5.8","Tissue RNA - testis [nTPM]":"4.1","Tissue RNA - thalamus [nTPM]":"4.2","Tissue RNA - thymus [nTPM]":"4.9","Tissue RNA - thyroid gland [nTPM]":"9.0","Tissue RNA - tongue [nTPM]":"9.1","Tissue RNA - tonsil [nTPM]":"4.7","Tissue RNA - urinary bladder [nTPM]":"6.8","Tissue RNA - vagina [nTPM]":"4.0","Tissue RNA - white matter [nTPM]":"6.1","Cell RNA - A-431 [nTPM]":"16.9","Cell RNA - A549 [nTPM]":"34.5","Cell RNA - AF22 [nTPM]":"16.1","Cell RNA - AN3-CA [nTPM]":"16.5","Cell RNA - ASC diff [nTPM]":"19.8","Cell RNA - ASC TERT1 [nTPM]":"24.4","Cell RNA - BEWO [nTPM]":"7.7","Cell RNA - BJ [nTPM]":"24.4","Cell RNA - BJ hTERT+ [nTPM]":"24.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"22.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.7","Cell RNA - CACO-2 [nTPM]":"13.8","Cell RNA - CAPAN-2 [nTPM]":"22.5","Cell RNA - Daudi [nTPM]":"14.6","Cell RNA - EFO-21 [nTPM]":"12.4","Cell RNA - fHDF\/TERT166 [nTPM]":"26.2","Cell RNA - GAMG [nTPM]":"44.4","Cell RNA - HaCaT [nTPM]":"15.4","Cell RNA - HAP1 [nTPM]":"22.4","Cell RNA - HBEC3-KT [nTPM]":"14.0","Cell RNA - HBF TERT88 [nTPM]":"27.9","Cell RNA - HDLM-2 [nTPM]":"10.9","Cell RNA - HEK 293 [nTPM]":"17.8","Cell RNA - HEL [nTPM]":"7.2","Cell RNA - HeLa [nTPM]":"19.7","Cell RNA - Hep G2 [nTPM]":"11.4","Cell RNA - HHSteC [nTPM]":"27.1","Cell RNA - HL-60 [nTPM]":"15.6","Cell RNA - HMC-1 [nTPM]":"6.8","Cell RNA - HSkMC [nTPM]":"23.2","Cell RNA - hTCEpi [nTPM]":"14.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"34.3","Cell RNA - hTERT-HME1 [nTPM]":"25.1","Cell RNA - hTERT-RPE1 [nTPM]":"23.0","Cell RNA - HUVEC TERT2 [nTPM]":"17.8","Cell RNA - JURKAT [nTPM]":"8.4","Cell RNA - K-562 [nTPM]":"20.3","Cell RNA - Karpas-707 [nTPM]":"15.8","Cell RNA - LHCN-M2 [nTPM]":"26.1","Cell RNA - MCF7 [nTPM]":"10.5","Cell RNA - MOLT-4 [nTPM]":"6.4","Cell RNA - NB-4 [nTPM]":"8.1","Cell RNA - NTERA-2 [nTPM]":"15.0","Cell RNA - OE19 [nTPM]":"8.8","Cell RNA - PC-3 [nTPM]":"25.1","Cell RNA - REH [nTPM]":"7.9","Cell RNA - RH-30 [nTPM]":"29.8","Cell RNA - RPMI-8226 [nTPM]":"16.4","Cell RNA - RPTEC TERT1 [nTPM]":"15.7","Cell RNA - RT4 [nTPM]":"8.4","Cell RNA - SCLC-21H [nTPM]":"3.9","Cell RNA - SH-SY5Y [nTPM]":"32.8","Cell RNA - SiHa [nTPM]":"34.3","Cell RNA - SK-BR-3 [nTPM]":"21.5","Cell RNA - SK-MEL-30 [nTPM]":"30.5","Cell RNA - SuSa [nTPM]":"21.3","Cell RNA - T-47d [nTPM]":"28.9","Cell RNA - THP-1 [nTPM]":"13.2","Cell RNA - TIME [nTPM]":"21.2","Cell RNA - U-138 MG [nTPM]":"28.4","Cell RNA - U-2 OS [nTPM]":"6.6","Cell RNA - U-2197 [nTPM]":"41.9","Cell RNA - U-251 MG [nTPM]":"18.5","Cell RNA - U-266\/70 [nTPM]":"19.1","Cell RNA - U-266\/84 [nTPM]":"26.0","Cell RNA - U-698 [nTPM]":"6.9","Cell RNA - U-87 MG [nTPM]":"31.6","Cell RNA - U-937 [nTPM]":"6.4","Cell RNA - WM-115 [nTPM]":"28.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.2","Blood RNA - eosinophil [nTPM]":"0.8","Blood RNA - gdT-cell [nTPM]":"2.2","Blood RNA - intermediate monocyte [nTPM]":"2.5","Blood RNA - MAIT T-cell [nTPM]":"2.0","Blood RNA - memory B-cell [nTPM]":"1.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.6","Blood RNA - memory CD8 T-cell [nTPM]":"2.0","Blood RNA - myeloid DC [nTPM]":"3.6","Blood RNA - naive B-cell [nTPM]":"1.7","Blood RNA - naive CD4 T-cell [nTPM]":"2.2","Blood RNA - naive CD8 T-cell [nTPM]":"2.6","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"2.6","Blood RNA - non-classical monocyte [nTPM]":"2.6","Blood RNA - plasmacytoid DC [nTPM]":"2.4","Blood RNA - T-reg [nTPM]":"3.2","Blood RNA - total PBMC [nTPM]":"1.7","Brain RNA - amygdala [nTPM]":"3.5","Brain RNA - basal ganglia [nTPM]":"4.0","Brain RNA - cerebellum [nTPM]":"7.8","Brain RNA - cerebral cortex [nTPM]":"4.9","Brain RNA - hippocampal formation [nTPM]":"3.7","Brain RNA - hypothalamus [nTPM]":"4.1","Brain RNA - medulla oblongata [nTPM]":"4.4","Brain RNA - midbrain [nTPM]":"4.1","Brain RNA - pons [nTPM]":"4.9","Brain RNA - spinal cord [nTPM]":"4.1","Brain RNA - thalamus [nTPM]":"4.2","Brain RNA - white matter [nTPM]":"6.1","Single Cell Type RNA - Adipocytes [nTPM]":"5.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.5","Single Cell Type RNA - Astrocytes [nTPM]":"16.6","Single Cell Type RNA - B-cells [nTPM]":"5.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"11.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"7.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.0","Single Cell Type RNA - dendritic cells [nTPM]":"2.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.5","Single Cell Type RNA - Endothelial cells [nTPM]":"5.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.1","Single Cell Type RNA - Fibroblasts [nTPM]":"10.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.7","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"14.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"18.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.4","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.4","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"9.2","Single Cell Type RNA - Langerhans cells [nTPM]":"4.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.9","Single Cell Type RNA - Leydig cells [nTPM]":"10.5","Single Cell Type RNA - Macrophages [nTPM]":"4.8","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"5.0","Single Cell Type RNA - Muller glia cells [nTPM]":"7.3","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"22.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.1","Single Cell Type RNA - Paneth cells [nTPM]":"2.4","Single Cell Type RNA - Peritubular cells [nTPM]":"13.2","Single Cell Type RNA - Plasma cells [nTPM]":"9.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.3","Single Cell Type RNA - Spermatocytes [nTPM]":"2.7","Single Cell Type RNA - Spermatogonia [nTPM]":"1.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.8","Single Cell Type RNA - T-cells [nTPM]":"5.1","Single Cell Type RNA - Theca cells [nTPM]":"12.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.3","Single Cell Type RNA - Urothelial cells [nTPM]":"4.9"},{"Gene":"MCCC1","Gene synonym":["MCCA"],"Ensembl":"ENSG00000078070","Gene description":"Methylcrotonoyl-CoA carboxylase 1","Uniprot":["Q96RQ3"],"Chromosome":"3","Position":"183015218-183116075","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Ligase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"T-47d":"153.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008310"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA008310":"AB_1853620"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.68e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Tissue RNA - adipose tissue [nTPM]":"37.9","Tissue RNA - adrenal gland [nTPM]":"22.6","Tissue RNA - amygdala [nTPM]":"9.5","Tissue RNA - appendix [nTPM]":"9.5","Tissue RNA - basal ganglia [nTPM]":"10.9","Tissue RNA - bone marrow [nTPM]":"13.9","Tissue RNA - breast [nTPM]":"33.2","Tissue RNA - cerebellum [nTPM]":"9.9","Tissue RNA - cerebral cortex [nTPM]":"13.4","Tissue RNA - cervix [nTPM]":"12.3","Tissue RNA - choroid plexus [nTPM]":"13.8","Tissue RNA - colon [nTPM]":"17.4","Tissue RNA - duodenum [nTPM]":"16.1","Tissue RNA - endometrium 1 [nTPM]":"10.1","Tissue RNA - epididymis [nTPM]":"14.6","Tissue RNA - esophagus [nTPM]":"17.6","Tissue RNA - fallopian tube [nTPM]":"12.2","Tissue RNA - gallbladder [nTPM]":"11.9","Tissue RNA - heart muscle [nTPM]":"34.2","Tissue RNA - hippocampal formation [nTPM]":"9.2","Tissue RNA - hypothalamus [nTPM]":"9.3","Tissue RNA - kidney [nTPM]":"58.8","Tissue RNA - liver [nTPM]":"59.3","Tissue RNA - lung [nTPM]":"17.9","Tissue RNA - lymph node [nTPM]":"11.7","Tissue RNA - medulla oblongata [nTPM]":"9.5","Tissue RNA - midbrain [nTPM]":"9.1","Tissue RNA - ovary [nTPM]":"17.2","Tissue RNA - pancreas [nTPM]":"31.2","Tissue RNA - parathyroid gland [nTPM]":"18.7","Tissue RNA - pituitary gland [nTPM]":"8.4","Tissue RNA - placenta [nTPM]":"6.3","Tissue RNA - pons [nTPM]":"10.6","Tissue RNA - prostate [nTPM]":"15.1","Tissue RNA - rectum [nTPM]":"18.6","Tissue RNA - retina [nTPM]":"10.8","Tissue RNA - salivary gland [nTPM]":"18.0","Tissue RNA - seminal vesicle [nTPM]":"13.4","Tissue RNA - skeletal muscle [nTPM]":"21.9","Tissue RNA - skin 1 [nTPM]":"12.2","Tissue RNA - small intestine [nTPM]":"13.8","Tissue RNA - smooth muscle [nTPM]":"10.6","Tissue RNA - spinal cord [nTPM]":"9.3","Tissue RNA - spleen [nTPM]":"11.8","Tissue RNA - stomach 1 [nTPM]":"21.7","Tissue RNA - testis [nTPM]":"9.1","Tissue RNA - thalamus [nTPM]":"11.1","Tissue RNA - thymus [nTPM]":"16.0","Tissue RNA - thyroid gland [nTPM]":"18.9","Tissue RNA - tongue [nTPM]":"26.3","Tissue RNA - tonsil [nTPM]":"15.5","Tissue RNA - urinary bladder [nTPM]":"26.5","Tissue RNA - vagina [nTPM]":"9.4","Tissue RNA - white matter [nTPM]":"13.3","Cell RNA - A-431 [nTPM]":"43.1","Cell RNA - A549 [nTPM]":"16.5","Cell RNA - AF22 [nTPM]":"10.3","Cell RNA - AN3-CA [nTPM]":"10.6","Cell RNA - ASC diff [nTPM]":"42.6","Cell RNA - ASC TERT1 [nTPM]":"19.1","Cell RNA - BEWO [nTPM]":"20.4","Cell RNA - BJ [nTPM]":"19.5","Cell RNA - BJ hTERT+ [nTPM]":"26.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.5","Cell RNA - CACO-2 [nTPM]":"22.9","Cell RNA - CAPAN-2 [nTPM]":"17.1","Cell RNA - Daudi [nTPM]":"47.6","Cell RNA - EFO-21 [nTPM]":"31.0","Cell RNA - fHDF\/TERT166 [nTPM]":"17.2","Cell RNA - GAMG [nTPM]":"35.8","Cell RNA - HaCaT [nTPM]":"22.0","Cell RNA - HAP1 [nTPM]":"15.4","Cell RNA - HBEC3-KT [nTPM]":"12.9","Cell RNA - HBF TERT88 [nTPM]":"26.4","Cell RNA - HDLM-2 [nTPM]":"16.6","Cell RNA - HEK 293 [nTPM]":"17.0","Cell RNA - HEL [nTPM]":"40.0","Cell RNA - HeLa [nTPM]":"18.3","Cell RNA - Hep G2 [nTPM]":"23.9","Cell RNA - HHSteC [nTPM]":"28.7","Cell RNA - HL-60 [nTPM]":"27.5","Cell RNA - HMC-1 [nTPM]":"22.0","Cell RNA - HSkMC [nTPM]":"21.6","Cell RNA - hTCEpi [nTPM]":"14.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.0","Cell RNA - hTERT-HME1 [nTPM]":"23.3","Cell RNA - hTERT-RPE1 [nTPM]":"14.0","Cell RNA - HUVEC TERT2 [nTPM]":"28.6","Cell RNA - JURKAT [nTPM]":"40.7","Cell RNA - K-562 [nTPM]":"22.7","Cell RNA - Karpas-707 [nTPM]":"24.7","Cell RNA - LHCN-M2 [nTPM]":"23.6","Cell RNA - MCF7 [nTPM]":"35.4","Cell RNA - MOLT-4 [nTPM]":"27.1","Cell RNA - NB-4 [nTPM]":"15.9","Cell RNA - NTERA-2 [nTPM]":"11.2","Cell RNA - OE19 [nTPM]":"66.3","Cell RNA - PC-3 [nTPM]":"17.9","Cell RNA - REH [nTPM]":"22.4","Cell RNA - RH-30 [nTPM]":"22.6","Cell RNA - RPMI-8226 [nTPM]":"60.1","Cell RNA - RPTEC TERT1 [nTPM]":"32.2","Cell RNA - RT4 [nTPM]":"67.2","Cell RNA - SCLC-21H [nTPM]":"22.0","Cell RNA - SH-SY5Y [nTPM]":"16.4","Cell RNA - SiHa [nTPM]":"75.3","Cell RNA - SK-BR-3 [nTPM]":"100.1","Cell RNA - SK-MEL-30 [nTPM]":"21.1","Cell RNA - SuSa [nTPM]":"10.7","Cell RNA - T-47d [nTPM]":"153.9","Cell RNA - THP-1 [nTPM]":"37.8","Cell RNA - TIME [nTPM]":"14.0","Cell RNA - U-138 MG [nTPM]":"15.8","Cell RNA - U-2 OS [nTPM]":"12.5","Cell RNA - U-2197 [nTPM]":"12.8","Cell RNA - U-251 MG [nTPM]":"28.6","Cell RNA - U-266\/70 [nTPM]":"24.3","Cell RNA - U-266\/84 [nTPM]":"48.8","Cell RNA - U-698 [nTPM]":"48.2","Cell RNA - U-87 MG [nTPM]":"16.8","Cell RNA - U-937 [nTPM]":"38.4","Cell RNA - WM-115 [nTPM]":"15.2","Blood RNA - basophil [nTPM]":"14.4","Blood RNA - classical monocyte [nTPM]":"13.3","Blood RNA - eosinophil [nTPM]":"25.0","Blood RNA - gdT-cell [nTPM]":"10.7","Blood RNA - intermediate monocyte [nTPM]":"15.6","Blood RNA - MAIT T-cell [nTPM]":"12.3","Blood RNA - memory B-cell [nTPM]":"17.9","Blood RNA - memory CD4 T-cell [nTPM]":"14.1","Blood RNA - memory CD8 T-cell [nTPM]":"11.8","Blood RNA - myeloid DC [nTPM]":"26.6","Blood RNA - naive B-cell [nTPM]":"15.4","Blood RNA - naive CD4 T-cell [nTPM]":"14.7","Blood RNA - naive CD8 T-cell [nTPM]":"13.1","Blood RNA - neutrophil [nTPM]":"2.1","Blood RNA - NK-cell [nTPM]":"25.4","Blood RNA - non-classical monocyte [nTPM]":"16.8","Blood RNA - plasmacytoid DC [nTPM]":"17.3","Blood RNA - T-reg [nTPM]":"9.6","Blood RNA - total PBMC [nTPM]":"10.7","Brain RNA - amygdala [nTPM]":"9.5","Brain RNA - basal ganglia [nTPM]":"10.9","Brain RNA - cerebellum [nTPM]":"9.9","Brain RNA - cerebral cortex [nTPM]":"13.4","Brain RNA - hippocampal formation [nTPM]":"9.2","Brain RNA - hypothalamus [nTPM]":"9.3","Brain RNA - medulla oblongata [nTPM]":"9.5","Brain RNA - midbrain [nTPM]":"9.1","Brain RNA - pons [nTPM]":"10.6","Brain RNA - spinal cord [nTPM]":"9.3","Brain RNA - thalamus [nTPM]":"11.1","Brain RNA - white matter [nTPM]":"13.3","Single Cell Type RNA - Adipocytes [nTPM]":"6.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"53.9","Single Cell Type RNA - Astrocytes [nTPM]":"44.7","Single Cell Type RNA - B-cells [nTPM]":"14.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Bipolar cells [nTPM]":"13.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"32.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"31.5","Single Cell Type RNA - Club cells [nTPM]":"20.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"35.4","Single Cell Type RNA - dendritic cells [nTPM]":"6.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"25.3","Single Cell Type RNA - Early spermatids [nTPM]":"5.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.2","Single Cell Type RNA - Endothelial cells [nTPM]":"6.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"10.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"66.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.4","Single Cell Type RNA - Fibroblasts [nTPM]":"10.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.9","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"19.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"36.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.5","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"56.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.6","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"11.1","Single Cell Type RNA - Langerhans cells [nTPM]":"8.6","Single Cell Type RNA - Late spermatids [nTPM]":"5.5","Single Cell Type RNA - Leydig cells [nTPM]":"8.7","Single Cell Type RNA - Macrophages [nTPM]":"10.5","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"44.0","Single Cell Type RNA - monocytes [nTPM]":"10.5","Single Cell Type RNA - Muller glia cells [nTPM]":"12.0","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"47.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"61.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.4","Single Cell Type RNA - Paneth cells [nTPM]":"15.8","Single Cell Type RNA - Peritubular cells [nTPM]":"10.5","Single Cell Type RNA - Plasma cells [nTPM]":"12.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"40.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.6","Single Cell Type RNA - Spermatocytes [nTPM]":"8.1","Single Cell Type RNA - Spermatogonia [nTPM]":"4.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"28.3","Single Cell Type RNA - T-cells [nTPM]":"10.1","Single Cell Type RNA - Theca cells [nTPM]":"24.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.5","Single Cell Type RNA - Urothelial cells [nTPM]":"21.7"},{"Gene":"MCCC2","Gene synonym":["MCCB"],"Ensembl":"ENSG00000131844","Gene description":"Methylcrotonoyl-CoA carboxylase 2","Uniprot":["Q9HCC0"],"Chromosome":"5","Position":"71587288-71658706","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Ligase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"120.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Glandular and luminal cells":"107.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"81.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038300","HPA038301","HPA061546"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA038300":"AB_2675941","HPA038301":"AB_10670661","HPA061546":"AB_2684557"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.62e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.70e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.43e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Tissue RNA - adipose tissue [nTPM]":"21.3","Tissue RNA - adrenal gland [nTPM]":"47.6","Tissue RNA - amygdala [nTPM]":"13.4","Tissue RNA - appendix [nTPM]":"13.5","Tissue RNA - basal ganglia [nTPM]":"13.7","Tissue RNA - bone marrow [nTPM]":"6.0","Tissue RNA - breast [nTPM]":"60.0","Tissue RNA - cerebellum [nTPM]":"12.4","Tissue RNA - cerebral cortex [nTPM]":"15.5","Tissue RNA - cervix [nTPM]":"21.3","Tissue RNA - choroid plexus [nTPM]":"24.9","Tissue RNA - colon [nTPM]":"30.5","Tissue RNA - duodenum [nTPM]":"27.2","Tissue RNA - endometrium 1 [nTPM]":"14.4","Tissue RNA - epididymis [nTPM]":"38.9","Tissue RNA - esophagus [nTPM]":"25.4","Tissue RNA - fallopian tube [nTPM]":"17.2","Tissue RNA - gallbladder [nTPM]":"15.2","Tissue RNA - heart muscle [nTPM]":"54.9","Tissue RNA - hippocampal formation [nTPM]":"12.0","Tissue RNA - hypothalamus [nTPM]":"13.1","Tissue RNA - kidney [nTPM]":"73.3","Tissue RNA - liver [nTPM]":"120.5","Tissue RNA - lung [nTPM]":"13.4","Tissue RNA - lymph node [nTPM]":"17.8","Tissue RNA - medulla oblongata [nTPM]":"14.8","Tissue RNA - midbrain [nTPM]":"13.4","Tissue RNA - ovary [nTPM]":"14.2","Tissue RNA - pancreas [nTPM]":"24.6","Tissue RNA - parathyroid gland [nTPM]":"32.8","Tissue RNA - pituitary gland [nTPM]":"14.1","Tissue RNA - placenta [nTPM]":"14.2","Tissue RNA - pons [nTPM]":"14.8","Tissue RNA - prostate [nTPM]":"48.2","Tissue RNA - rectum [nTPM]":"35.9","Tissue RNA - retina [nTPM]":"12.2","Tissue RNA - salivary gland [nTPM]":"28.2","Tissue RNA - seminal vesicle [nTPM]":"20.6","Tissue RNA - skeletal muscle [nTPM]":"34.4","Tissue RNA - skin 1 [nTPM]":"19.8","Tissue RNA - small intestine [nTPM]":"20.7","Tissue RNA - smooth muscle [nTPM]":"11.7","Tissue RNA - spinal cord [nTPM]":"16.3","Tissue RNA - spleen [nTPM]":"15.6","Tissue RNA - stomach 1 [nTPM]":"25.8","Tissue RNA - testis [nTPM]":"8.6","Tissue RNA - thalamus [nTPM]":"16.0","Tissue RNA - thymus [nTPM]":"14.2","Tissue RNA - thyroid gland [nTPM]":"44.6","Tissue RNA - tongue [nTPM]":"35.4","Tissue RNA - tonsil [nTPM]":"21.5","Tissue RNA - urinary bladder [nTPM]":"27.0","Tissue RNA - vagina [nTPM]":"15.0","Tissue RNA - white matter [nTPM]":"18.4","Cell RNA - A-431 [nTPM]":"38.5","Cell RNA - A549 [nTPM]":"52.4","Cell RNA - AF22 [nTPM]":"21.4","Cell RNA - AN3-CA [nTPM]":"82.5","Cell RNA - ASC diff [nTPM]":"22.4","Cell RNA - ASC TERT1 [nTPM]":"23.0","Cell RNA - BEWO [nTPM]":"36.9","Cell RNA - BJ [nTPM]":"16.4","Cell RNA - BJ hTERT+ [nTPM]":"29.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"35.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"25.7","Cell RNA - CACO-2 [nTPM]":"91.1","Cell RNA - CAPAN-2 [nTPM]":"46.9","Cell RNA - Daudi [nTPM]":"90.4","Cell RNA - EFO-21 [nTPM]":"62.8","Cell RNA - fHDF\/TERT166 [nTPM]":"25.9","Cell RNA - GAMG [nTPM]":"28.0","Cell RNA - HaCaT [nTPM]":"30.8","Cell RNA - HAP1 [nTPM]":"37.8","Cell RNA - HBEC3-KT [nTPM]":"58.8","Cell RNA - HBF TERT88 [nTPM]":"44.3","Cell RNA - HDLM-2 [nTPM]":"47.6","Cell RNA - HEK 293 [nTPM]":"45.6","Cell RNA - HEL [nTPM]":"48.2","Cell RNA - HeLa [nTPM]":"24.7","Cell RNA - Hep G2 [nTPM]":"100.5","Cell RNA - HHSteC [nTPM]":"39.2","Cell RNA - HL-60 [nTPM]":"24.4","Cell RNA - HMC-1 [nTPM]":"42.8","Cell RNA - HSkMC [nTPM]":"29.5","Cell RNA - hTCEpi [nTPM]":"30.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.6","Cell RNA - hTERT-HME1 [nTPM]":"25.8","Cell RNA - hTERT-RPE1 [nTPM]":"15.8","Cell RNA - HUVEC TERT2 [nTPM]":"31.7","Cell RNA - JURKAT [nTPM]":"24.9","Cell RNA - K-562 [nTPM]":"63.2","Cell RNA - Karpas-707 [nTPM]":"31.6","Cell RNA - LHCN-M2 [nTPM]":"24.9","Cell RNA - MCF7 [nTPM]":"103.0","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"42.9","Cell RNA - NTERA-2 [nTPM]":"29.0","Cell RNA - OE19 [nTPM]":"33.2","Cell RNA - PC-3 [nTPM]":"27.2","Cell RNA - REH [nTPM]":"46.3","Cell RNA - RH-30 [nTPM]":"64.5","Cell RNA - RPMI-8226 [nTPM]":"130.9","Cell RNA - RPTEC TERT1 [nTPM]":"92.5","Cell RNA - RT4 [nTPM]":"66.9","Cell RNA - SCLC-21H [nTPM]":"32.9","Cell RNA - SH-SY5Y [nTPM]":"36.7","Cell RNA - SiHa [nTPM]":"80.1","Cell RNA - SK-BR-3 [nTPM]":"111.8","Cell RNA - SK-MEL-30 [nTPM]":"38.8","Cell RNA - SuSa [nTPM]":"10.1","Cell RNA - T-47d [nTPM]":"92.7","Cell RNA - THP-1 [nTPM]":"59.6","Cell RNA - TIME [nTPM]":"22.7","Cell RNA - U-138 MG [nTPM]":"14.4","Cell RNA - U-2 OS [nTPM]":"22.1","Cell RNA - U-2197 [nTPM]":"26.1","Cell RNA - U-251 MG [nTPM]":"49.9","Cell RNA - U-266\/70 [nTPM]":"22.4","Cell RNA - U-266\/84 [nTPM]":"46.2","Cell RNA - U-698 [nTPM]":"54.6","Cell RNA - U-87 MG [nTPM]":"23.7","Cell RNA - U-937 [nTPM]":"66.3","Cell RNA - WM-115 [nTPM]":"36.6","Blood RNA - basophil [nTPM]":"2.0","Blood RNA - classical monocyte [nTPM]":"8.4","Blood RNA - eosinophil [nTPM]":"1.9","Blood RNA - gdT-cell [nTPM]":"6.5","Blood RNA - intermediate monocyte [nTPM]":"13.5","Blood RNA - MAIT T-cell [nTPM]":"8.5","Blood RNA - memory B-cell [nTPM]":"9.7","Blood RNA - memory CD4 T-cell [nTPM]":"8.4","Blood RNA - memory CD8 T-cell [nTPM]":"7.4","Blood RNA - myeloid DC [nTPM]":"19.4","Blood RNA - naive B-cell [nTPM]":"9.9","Blood RNA - naive CD4 T-cell [nTPM]":"8.3","Blood RNA - naive CD8 T-cell [nTPM]":"9.1","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"14.7","Blood RNA - non-classical monocyte [nTPM]":"8.1","Blood RNA - plasmacytoid DC [nTPM]":"8.1","Blood RNA - T-reg [nTPM]":"12.1","Blood RNA - total PBMC [nTPM]":"8.3","Brain RNA - amygdala [nTPM]":"13.4","Brain RNA - basal ganglia [nTPM]":"13.7","Brain RNA - cerebellum [nTPM]":"12.4","Brain RNA - cerebral cortex [nTPM]":"15.5","Brain RNA - hippocampal formation [nTPM]":"12.0","Brain RNA - hypothalamus [nTPM]":"13.1","Brain RNA - medulla oblongata [nTPM]":"14.8","Brain RNA - midbrain [nTPM]":"13.4","Brain RNA - pons [nTPM]":"14.8","Brain RNA - spinal cord [nTPM]":"16.3","Brain RNA - thalamus [nTPM]":"16.0","Brain RNA - white matter [nTPM]":"18.4","Single Cell Type RNA - Adipocytes [nTPM]":"9.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.6","Single Cell Type RNA - Astrocytes [nTPM]":"27.4","Single Cell Type RNA - B-cells [nTPM]":"26.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"20.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.2","Single Cell Type RNA - Bipolar cells [nTPM]":"12.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"54.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"28.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"61.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"22.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"48.5","Single Cell Type RNA - dendritic cells [nTPM]":"17.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"26.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"20.6","Single Cell Type RNA - Early spermatids [nTPM]":"4.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"94.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"24.0","Single Cell Type RNA - Endothelial cells [nTPM]":"15.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"29.5","Single Cell Type RNA - Erythroid cells [nTPM]":"13.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"23.0","Single Cell Type RNA - Fibroblasts [nTPM]":"13.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"30.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"107.0","Single Cell Type RNA - granulocytes [nTPM]":"12.7","Single Cell Type RNA - Granulosa cells [nTPM]":"22.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.7","Single Cell Type RNA - Hepatocytes [nTPM]":"93.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"22.8","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"12.1","Single Cell Type RNA - Langerhans cells [nTPM]":"11.2","Single Cell Type RNA - Late spermatids [nTPM]":"9.8","Single Cell Type RNA - Leydig cells [nTPM]":"13.7","Single Cell Type RNA - Macrophages [nTPM]":"14.0","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"17.9","Single Cell Type RNA - Muller glia cells [nTPM]":"15.4","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"30.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"28.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.3","Single Cell Type RNA - Paneth cells [nTPM]":"17.0","Single Cell Type RNA - Peritubular cells [nTPM]":"20.3","Single Cell Type RNA - Plasma cells [nTPM]":"27.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"29.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"59.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.0","Single Cell Type RNA - Spermatocytes [nTPM]":"4.2","Single Cell Type RNA - Spermatogonia [nTPM]":"12.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"35.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"63.6","Single Cell Type RNA - T-cells [nTPM]":"17.9","Single Cell Type RNA - Theca cells [nTPM]":"30.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"33.9","Single Cell Type RNA - Urothelial cells [nTPM]":"20.9"},{"Gene":"MCEE","Gene synonym":["GLOD2","MCE"],"Ensembl":"ENSG00000124370","Gene description":"Methylmalonyl-CoA epimerase","Uniprot":["Q96PE7"],"Chromosome":"2","Position":"71109684-71130239","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Isomerase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"92.0","Proximal tubular cells":"77.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035196"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli"],"Secretome location":"Intracellular and membrane","CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"29000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 30: Mammary glandular cells - Lactation","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA035196":"AB_10601871"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.76e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.78e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"},"Tissue RNA - adipose tissue [nTPM]":"17.8","Tissue RNA - adrenal gland [nTPM]":"30.0","Tissue RNA - amygdala [nTPM]":"8.9","Tissue RNA - appendix [nTPM]":"12.3","Tissue RNA - basal ganglia [nTPM]":"9.7","Tissue RNA - bone marrow [nTPM]":"9.1","Tissue RNA - breast [nTPM]":"32.7","Tissue RNA - cerebellum [nTPM]":"10.5","Tissue RNA - cerebral cortex [nTPM]":"12.5","Tissue RNA - cervix [nTPM]":"22.1","Tissue RNA - choroid plexus [nTPM]":"15.4","Tissue RNA - colon [nTPM]":"20.1","Tissue RNA - duodenum [nTPM]":"20.1","Tissue RNA - endometrium 1 [nTPM]":"13.1","Tissue RNA - epididymis [nTPM]":"30.5","Tissue RNA - esophagus [nTPM]":"26.3","Tissue RNA - fallopian tube [nTPM]":"14.8","Tissue RNA - gallbladder [nTPM]":"14.2","Tissue RNA - heart muscle [nTPM]":"35.9","Tissue RNA - hippocampal formation [nTPM]":"8.9","Tissue RNA - hypothalamus [nTPM]":"9.4","Tissue RNA - kidney [nTPM]":"33.7","Tissue RNA - liver [nTPM]":"69.8","Tissue RNA - lung [nTPM]":"13.7","Tissue RNA - lymph node [nTPM]":"14.7","Tissue RNA - medulla oblongata [nTPM]":"9.5","Tissue RNA - midbrain [nTPM]":"9.1","Tissue RNA - ovary [nTPM]":"18.5","Tissue RNA - pancreas [nTPM]":"36.1","Tissue RNA - parathyroid gland [nTPM]":"35.6","Tissue RNA - pituitary gland [nTPM]":"24.1","Tissue RNA - placenta [nTPM]":"17.6","Tissue RNA - pons [nTPM]":"9.9","Tissue RNA - prostate [nTPM]":"23.9","Tissue RNA - rectum [nTPM]":"23.9","Tissue RNA - retina [nTPM]":"12.3","Tissue RNA - salivary gland [nTPM]":"42.8","Tissue RNA - seminal vesicle [nTPM]":"17.8","Tissue RNA - skeletal muscle [nTPM]":"36.5","Tissue RNA - skin 1 [nTPM]":"28.4","Tissue RNA - small intestine [nTPM]":"16.9","Tissue RNA - smooth muscle [nTPM]":"12.2","Tissue RNA - spinal cord [nTPM]":"9.7","Tissue RNA - spleen [nTPM]":"16.0","Tissue RNA - stomach 1 [nTPM]":"23.5","Tissue RNA - testis [nTPM]":"6.0","Tissue RNA - thalamus [nTPM]":"9.4","Tissue RNA - thymus [nTPM]":"13.3","Tissue RNA - thyroid gland [nTPM]":"14.1","Tissue RNA - tongue [nTPM]":"61.7","Tissue RNA - tonsil [nTPM]":"15.5","Tissue RNA - urinary bladder [nTPM]":"16.5","Tissue RNA - vagina [nTPM]":"21.9","Tissue RNA - white matter [nTPM]":"11.7","Cell RNA - A-431 [nTPM]":"12.1","Cell RNA - A549 [nTPM]":"5.2","Cell RNA - AF22 [nTPM]":"10.6","Cell RNA - AN3-CA [nTPM]":"7.6","Cell RNA - ASC diff [nTPM]":"34.3","Cell RNA - ASC TERT1 [nTPM]":"46.6","Cell RNA - BEWO [nTPM]":"30.2","Cell RNA - BJ [nTPM]":"18.5","Cell RNA - BJ hTERT+ [nTPM]":"23.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.9","Cell RNA - CACO-2 [nTPM]":"14.7","Cell RNA - CAPAN-2 [nTPM]":"14.8","Cell RNA - Daudi [nTPM]":"18.7","Cell RNA - EFO-21 [nTPM]":"5.5","Cell RNA - fHDF\/TERT166 [nTPM]":"18.5","Cell RNA - GAMG [nTPM]":"7.0","Cell RNA - HaCaT [nTPM]":"12.5","Cell RNA - HAP1 [nTPM]":"12.4","Cell RNA - HBEC3-KT [nTPM]":"9.6","Cell RNA - HBF TERT88 [nTPM]":"9.5","Cell RNA - HDLM-2 [nTPM]":"17.1","Cell RNA - HEK 293 [nTPM]":"10.7","Cell RNA - HEL [nTPM]":"12.7","Cell RNA - HeLa [nTPM]":"16.3","Cell RNA - Hep G2 [nTPM]":"42.5","Cell RNA - HHSteC [nTPM]":"19.5","Cell RNA - HL-60 [nTPM]":"14.5","Cell RNA - HMC-1 [nTPM]":"10.3","Cell RNA - HSkMC [nTPM]":"31.3","Cell RNA - hTCEpi [nTPM]":"13.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.2","Cell RNA - hTERT-HME1 [nTPM]":"12.3","Cell RNA - hTERT-RPE1 [nTPM]":"20.5","Cell RNA - HUVEC TERT2 [nTPM]":"10.6","Cell RNA - JURKAT [nTPM]":"14.6","Cell RNA - K-562 [nTPM]":"17.1","Cell RNA - Karpas-707 [nTPM]":"31.9","Cell RNA - LHCN-M2 [nTPM]":"9.1","Cell RNA - MCF7 [nTPM]":"15.5","Cell RNA - MOLT-4 [nTPM]":"10.9","Cell RNA - NB-4 [nTPM]":"16.9","Cell RNA - NTERA-2 [nTPM]":"9.6","Cell RNA - OE19 [nTPM]":"33.1","Cell RNA - PC-3 [nTPM]":"14.6","Cell RNA - REH [nTPM]":"12.8","Cell RNA - RH-30 [nTPM]":"12.3","Cell RNA - RPMI-8226 [nTPM]":"35.2","Cell RNA - RPTEC TERT1 [nTPM]":"14.8","Cell RNA - RT4 [nTPM]":"10.4","Cell RNA - SCLC-21H [nTPM]":"11.9","Cell RNA - SH-SY5Y [nTPM]":"8.8","Cell RNA - SiHa [nTPM]":"6.9","Cell RNA - SK-BR-3 [nTPM]":"40.1","Cell RNA - SK-MEL-30 [nTPM]":"18.1","Cell RNA - SuSa [nTPM]":"12.1","Cell RNA - T-47d [nTPM]":"31.7","Cell RNA - THP-1 [nTPM]":"13.4","Cell RNA - TIME [nTPM]":"13.7","Cell RNA - U-138 MG [nTPM]":"10.6","Cell RNA - U-2 OS [nTPM]":"8.3","Cell RNA - U-2197 [nTPM]":"10.9","Cell RNA - U-251 MG [nTPM]":"7.5","Cell RNA - U-266\/70 [nTPM]":"30.7","Cell RNA - U-266\/84 [nTPM]":"13.1","Cell RNA - U-698 [nTPM]":"20.0","Cell RNA - U-87 MG [nTPM]":"17.5","Cell RNA - U-937 [nTPM]":"23.7","Cell RNA - WM-115 [nTPM]":"9.9","Blood RNA - basophil [nTPM]":"20.3","Blood RNA - classical monocyte [nTPM]":"23.2","Blood RNA - eosinophil [nTPM]":"27.6","Blood RNA - gdT-cell [nTPM]":"15.4","Blood RNA - intermediate monocyte [nTPM]":"25.6","Blood RNA - MAIT T-cell [nTPM]":"21.9","Blood RNA - memory B-cell [nTPM]":"21.6","Blood RNA - memory CD4 T-cell [nTPM]":"19.3","Blood RNA - memory CD8 T-cell [nTPM]":"15.5","Blood RNA - myeloid DC [nTPM]":"19.9","Blood RNA - naive B-cell [nTPM]":"16.7","Blood RNA - naive CD4 T-cell [nTPM]":"17.6","Blood RNA - naive CD8 T-cell [nTPM]":"15.0","Blood RNA - neutrophil [nTPM]":"6.1","Blood RNA - NK-cell [nTPM]":"16.5","Blood RNA - non-classical monocyte [nTPM]":"25.3","Blood RNA - plasmacytoid DC [nTPM]":"23.9","Blood RNA - T-reg [nTPM]":"35.3","Blood RNA - total PBMC [nTPM]":"14.6","Brain RNA - amygdala [nTPM]":"8.9","Brain RNA - basal ganglia [nTPM]":"9.7","Brain RNA - cerebellum [nTPM]":"10.5","Brain RNA - cerebral cortex [nTPM]":"12.5","Brain RNA - hippocampal formation [nTPM]":"8.9","Brain RNA - hypothalamus [nTPM]":"9.4","Brain RNA - medulla oblongata [nTPM]":"9.5","Brain RNA - midbrain [nTPM]":"9.1","Brain RNA - pons [nTPM]":"9.9","Brain RNA - spinal cord [nTPM]":"9.7","Brain RNA - thalamus [nTPM]":"9.4","Brain RNA - white matter [nTPM]":"11.7","Single Cell Type RNA - Adipocytes [nTPM]":"11.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.4","Single Cell Type RNA - Astrocytes [nTPM]":"13.7","Single Cell Type RNA - B-cells [nTPM]":"12.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.6","Single Cell Type RNA - Bipolar cells [nTPM]":"2.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"37.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"27.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"75.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"18.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"36.2","Single Cell Type RNA - dendritic cells [nTPM]":"11.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"92.0","Single Cell Type RNA - Ductal cells [nTPM]":"13.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.2","Single Cell Type RNA - Endothelial cells [nTPM]":"9.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.0","Single Cell Type RNA - Erythroid cells [nTPM]":"12.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"36.8","Single Cell Type RNA - Fibroblasts [nTPM]":"23.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"5.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.8","Single Cell Type RNA - Hepatocytes [nTPM]":"73.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.1","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"32.5","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"10.4","Single Cell Type RNA - Langerhans cells [nTPM]":"8.7","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"29.2","Single Cell Type RNA - Macrophages [nTPM]":"9.4","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"9.1","Single Cell Type RNA - Muller glia cells [nTPM]":"7.3","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.6","Single Cell Type RNA - Paneth cells [nTPM]":"16.2","Single Cell Type RNA - Peritubular cells [nTPM]":"17.7","Single Cell Type RNA - Plasma cells [nTPM]":"42.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"35.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"77.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.6","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.9","Single Cell Type RNA - Spermatocytes [nTPM]":"3.7","Single Cell Type RNA - Spermatogonia [nTPM]":"5.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.4","Single Cell Type RNA - T-cells [nTPM]":"10.1","Single Cell Type RNA - Theca cells [nTPM]":"16.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.0","Single Cell Type RNA - Urothelial cells [nTPM]":"11.9"},{"Gene":"MCFD2","Gene synonym":["F5F8D","LMAN1IP","SDNSF"],"Ensembl":"ENSG00000180398","Gene description":"Multiple coagulation factor deficiency 2, ER cargo receptor complex subunit","Uniprot":["Q8NI22"],"Chromosome":"2","Position":"46901870-46941855","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["ER-Golgi transport","Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Muller glia cells":"253.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022410","HPA034593"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1200000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 5: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022410":null,"HPA034593":"AB_2674239"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.64e-4"},"Tissue RNA - adipose tissue [nTPM]":"52.0","Tissue RNA - adrenal gland [nTPM]":"155.5","Tissue RNA - amygdala [nTPM]":"41.3","Tissue RNA - appendix [nTPM]":"35.6","Tissue RNA - basal ganglia [nTPM]":"43.1","Tissue RNA - bone marrow [nTPM]":"34.7","Tissue RNA - breast [nTPM]":"55.1","Tissue RNA - cerebellum [nTPM]":"38.1","Tissue RNA - cerebral cortex [nTPM]":"40.3","Tissue RNA - cervix [nTPM]":"50.4","Tissue RNA - choroid plexus [nTPM]":"69.5","Tissue RNA - colon [nTPM]":"32.2","Tissue RNA - duodenum [nTPM]":"32.5","Tissue RNA - endometrium 1 [nTPM]":"54.5","Tissue RNA - epididymis [nTPM]":"42.1","Tissue RNA - esophagus [nTPM]":"45.9","Tissue RNA - fallopian tube [nTPM]":"41.9","Tissue RNA - gallbladder [nTPM]":"44.9","Tissue RNA - heart muscle [nTPM]":"42.3","Tissue RNA - hippocampal formation [nTPM]":"41.3","Tissue RNA - hypothalamus [nTPM]":"46.8","Tissue RNA - kidney [nTPM]":"59.4","Tissue RNA - liver [nTPM]":"111.8","Tissue RNA - lung [nTPM]":"45.0","Tissue RNA - lymph node [nTPM]":"32.1","Tissue RNA - medulla oblongata [nTPM]":"33.5","Tissue RNA - midbrain [nTPM]":"41.3","Tissue RNA - ovary [nTPM]":"79.2","Tissue RNA - pancreas [nTPM]":"104.1","Tissue RNA - parathyroid gland [nTPM]":"52.5","Tissue RNA - pituitary gland [nTPM]":"38.7","Tissue RNA - placenta [nTPM]":"70.1","Tissue RNA - pons [nTPM]":"41.6","Tissue RNA - prostate [nTPM]":"54.0","Tissue RNA - rectum [nTPM]":"26.9","Tissue RNA - retina [nTPM]":"83.3","Tissue RNA - salivary gland [nTPM]":"149.7","Tissue RNA - seminal vesicle [nTPM]":"82.9","Tissue RNA - skeletal muscle [nTPM]":"83.3","Tissue RNA - skin 1 [nTPM]":"26.0","Tissue RNA - small intestine [nTPM]":"33.4","Tissue RNA - smooth muscle [nTPM]":"52.5","Tissue RNA - spinal cord [nTPM]":"28.0","Tissue RNA - spleen [nTPM]":"44.6","Tissue RNA - stomach 1 [nTPM]":"33.9","Tissue RNA - testis [nTPM]":"30.9","Tissue RNA - thalamus [nTPM]":"48.6","Tissue RNA - thymus [nTPM]":"30.8","Tissue RNA - thyroid gland [nTPM]":"121.0","Tissue RNA - tongue [nTPM]":"84.6","Tissue RNA - tonsil [nTPM]":"34.2","Tissue RNA - urinary bladder [nTPM]":"41.2","Tissue RNA - vagina [nTPM]":"29.2","Tissue RNA - white matter [nTPM]":"34.7","Cell RNA - A-431 [nTPM]":"147.7","Cell RNA - A549 [nTPM]":"86.9","Cell RNA - AF22 [nTPM]":"74.7","Cell RNA - AN3-CA [nTPM]":"59.7","Cell RNA - ASC diff [nTPM]":"151.5","Cell RNA - ASC TERT1 [nTPM]":"215.1","Cell RNA - BEWO [nTPM]":"115.4","Cell RNA - BJ [nTPM]":"248.4","Cell RNA - BJ hTERT+ [nTPM]":"254.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"129.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"116.8","Cell RNA - CACO-2 [nTPM]":"116.9","Cell RNA - CAPAN-2 [nTPM]":"109.4","Cell RNA - Daudi [nTPM]":"96.4","Cell RNA - EFO-21 [nTPM]":"297.7","Cell RNA - fHDF\/TERT166 [nTPM]":"294.7","Cell RNA - GAMG [nTPM]":"154.3","Cell RNA - HaCaT [nTPM]":"81.8","Cell RNA - HAP1 [nTPM]":"67.0","Cell RNA - HBEC3-KT [nTPM]":"127.0","Cell RNA - HBF TERT88 [nTPM]":"207.7","Cell RNA - HDLM-2 [nTPM]":"64.5","Cell RNA - HEK 293 [nTPM]":"67.2","Cell RNA - HEL [nTPM]":"101.9","Cell RNA - HeLa [nTPM]":"87.1","Cell RNA - Hep G2 [nTPM]":"182.5","Cell RNA - HHSteC [nTPM]":"236.5","Cell RNA - HL-60 [nTPM]":"94.8","Cell RNA - HMC-1 [nTPM]":"158.6","Cell RNA - HSkMC [nTPM]":"163.2","Cell RNA - hTCEpi [nTPM]":"77.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"206.7","Cell RNA - hTERT-HME1 [nTPM]":"178.7","Cell RNA - hTERT-RPE1 [nTPM]":"247.9","Cell RNA - HUVEC TERT2 [nTPM]":"210.8","Cell RNA - JURKAT [nTPM]":"28.0","Cell RNA - K-562 [nTPM]":"199.3","Cell RNA - Karpas-707 [nTPM]":"56.0","Cell RNA - LHCN-M2 [nTPM]":"266.8","Cell RNA - MCF7 [nTPM]":"48.7","Cell RNA - MOLT-4 [nTPM]":"56.9","Cell RNA - NB-4 [nTPM]":"67.6","Cell RNA - NTERA-2 [nTPM]":"63.9","Cell RNA - OE19 [nTPM]":"102.3","Cell RNA - PC-3 [nTPM]":"84.1","Cell RNA - REH [nTPM]":"68.3","Cell RNA - RH-30 [nTPM]":"133.2","Cell RNA - RPMI-8226 [nTPM]":"106.7","Cell RNA - RPTEC TERT1 [nTPM]":"80.3","Cell RNA - RT4 [nTPM]":"59.3","Cell RNA - SCLC-21H [nTPM]":"23.9","Cell RNA - SH-SY5Y [nTPM]":"62.2","Cell RNA - SiHa [nTPM]":"93.1","Cell RNA - SK-BR-3 [nTPM]":"46.9","Cell RNA - SK-MEL-30 [nTPM]":"116.0","Cell RNA - SuSa [nTPM]":"86.3","Cell RNA - T-47d [nTPM]":"33.1","Cell RNA - THP-1 [nTPM]":"80.6","Cell RNA - TIME [nTPM]":"341.1","Cell RNA - U-138 MG [nTPM]":"298.3","Cell RNA - U-2 OS [nTPM]":"130.5","Cell RNA - U-2197 [nTPM]":"97.0","Cell RNA - U-251 MG [nTPM]":"164.2","Cell RNA - U-266\/70 [nTPM]":"42.0","Cell RNA - U-266\/84 [nTPM]":"43.8","Cell RNA - U-698 [nTPM]":"76.4","Cell RNA - U-87 MG [nTPM]":"320.2","Cell RNA - U-937 [nTPM]":"88.0","Cell RNA - WM-115 [nTPM]":"100.8","Blood RNA - basophil [nTPM]":"27.2","Blood RNA - classical monocyte [nTPM]":"21.4","Blood RNA - eosinophil [nTPM]":"29.7","Blood RNA - gdT-cell [nTPM]":"9.6","Blood RNA - intermediate monocyte [nTPM]":"23.3","Blood RNA - MAIT T-cell [nTPM]":"12.2","Blood RNA - memory B-cell [nTPM]":"12.5","Blood RNA - memory CD4 T-cell [nTPM]":"10.9","Blood RNA - memory CD8 T-cell [nTPM]":"10.2","Blood RNA - myeloid DC [nTPM]":"18.4","Blood RNA - naive B-cell [nTPM]":"12.8","Blood RNA - naive CD4 T-cell [nTPM]":"14.3","Blood RNA - naive CD8 T-cell [nTPM]":"9.8","Blood RNA - neutrophil [nTPM]":"12.0","Blood RNA - NK-cell [nTPM]":"9.9","Blood RNA - non-classical monocyte [nTPM]":"18.3","Blood RNA - plasmacytoid DC [nTPM]":"16.9","Blood RNA - T-reg [nTPM]":"9.7","Blood RNA - total PBMC [nTPM]":"14.0","Brain RNA - amygdala [nTPM]":"41.3","Brain RNA - basal ganglia [nTPM]":"43.1","Brain RNA - cerebellum [nTPM]":"38.1","Brain RNA - cerebral cortex [nTPM]":"40.3","Brain RNA - hippocampal formation [nTPM]":"41.3","Brain RNA - hypothalamus [nTPM]":"46.8","Brain RNA - medulla oblongata [nTPM]":"33.5","Brain RNA - midbrain [nTPM]":"41.3","Brain RNA - pons [nTPM]":"41.6","Brain RNA - spinal cord [nTPM]":"28.0","Brain RNA - thalamus [nTPM]":"48.6","Brain RNA - white matter [nTPM]":"34.7","Single Cell Type RNA - Adipocytes [nTPM]":"50.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"105.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"89.1","Single Cell Type RNA - Astrocytes [nTPM]":"16.6","Single Cell Type RNA - B-cells [nTPM]":"29.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"48.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"56.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"65.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"36.5","Single Cell Type RNA - Bipolar cells [nTPM]":"69.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"64.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"48.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"70.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"68.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"47.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"75.5","Single Cell Type RNA - dendritic cells [nTPM]":"25.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"26.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"88.6","Single Cell Type RNA - Early spermatids [nTPM]":"144.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"76.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"60.2","Single Cell Type RNA - Endothelial cells [nTPM]":"64.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"26.8","Single Cell Type RNA - Erythroid cells [nTPM]":"28.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"178.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"64.5","Single Cell Type RNA - Fibroblasts [nTPM]":"70.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"69.9","Single Cell Type RNA - granulocytes [nTPM]":"50.5","Single Cell Type RNA - Granulosa cells [nTPM]":"44.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"53.9","Single Cell Type RNA - Hepatocytes [nTPM]":"155.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"54.5","Single Cell Type RNA - Horizontal cells [nTPM]":"38.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"23.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.5","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"40.5","Single Cell Type RNA - Langerhans cells [nTPM]":"31.3","Single Cell Type RNA - Late spermatids [nTPM]":"113.7","Single Cell Type RNA - Leydig cells [nTPM]":"62.7","Single Cell Type RNA - Macrophages [nTPM]":"39.2","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"33.8","Single Cell Type RNA - Muller glia cells [nTPM]":"253.2","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"152.7","Single Cell Type RNA - Paneth cells [nTPM]":"23.1","Single Cell Type RNA - Peritubular cells [nTPM]":"59.5","Single Cell Type RNA - Plasma cells [nTPM]":"43.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"82.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"42.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"41.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"69.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"51.3","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"63.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"55.4","Single Cell Type RNA - Spermatocytes [nTPM]":"48.9","Single Cell Type RNA - Spermatogonia [nTPM]":"32.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"39.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"44.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"102.1","Single Cell Type RNA - T-cells [nTPM]":"23.4","Single Cell Type RNA - Theca cells [nTPM]":"74.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"22.8","Single Cell Type RNA - Urothelial cells [nTPM]":"75.8"},{"Gene":"MCM2","Gene synonym":["BM28","CCNL1","cdc19","CDCL1","D3S3194","DFNA70","KIAA0030"],"Ensembl":"ENSG00000073111","Gene description":"Minichromosome maintenance complex component 2","Uniprot":["P49736"],"Chromosome":"3","Position":"127598410-127622436","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA replication"],"Molecular function":["DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Cancer-related genes","Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"67.7","lymphoid tissue":"37.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"63.3","Erythroid cells":"65.6","Extravillous trophoblasts":"28.8","Spermatogonia":"25.9","Syncytiotrophoblasts":"33.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000303","HPA031450","HPA031495","HPA031496"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"120000","Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB000303":"AB_322519","HPA031450":null,"HPA031495":"AB_2673904","HPA031496":"AB_2673905"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.66e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.51e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.1","Tissue RNA - adrenal gland [nTPM]":"3.4","Tissue RNA - amygdala [nTPM]":"2.0","Tissue RNA - appendix [nTPM]":"16.4","Tissue RNA - basal ganglia [nTPM]":"1.9","Tissue RNA - bone marrow [nTPM]":"67.7","Tissue RNA - breast [nTPM]":"6.2","Tissue RNA - cerebellum [nTPM]":"2.5","Tissue RNA - cerebral cortex [nTPM]":"1.9","Tissue RNA - cervix [nTPM]":"5.3","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"9.2","Tissue RNA - duodenum [nTPM]":"8.1","Tissue RNA - endometrium 1 [nTPM]":"5.0","Tissue RNA - epididymis [nTPM]":"2.4","Tissue RNA - esophagus [nTPM]":"11.0","Tissue RNA - fallopian tube [nTPM]":"7.6","Tissue RNA - gallbladder [nTPM]":"2.5","Tissue RNA - heart muscle [nTPM]":"6.4","Tissue RNA - hippocampal formation [nTPM]":"1.9","Tissue RNA - hypothalamus [nTPM]":"1.8","Tissue RNA - kidney [nTPM]":"3.4","Tissue RNA - liver [nTPM]":"6.3","Tissue RNA - lung [nTPM]":"3.4","Tissue RNA - lymph node [nTPM]":"26.8","Tissue RNA - medulla oblongata [nTPM]":"2.3","Tissue RNA - midbrain [nTPM]":"1.9","Tissue RNA - ovary [nTPM]":"6.4","Tissue RNA - pancreas [nTPM]":"3.0","Tissue RNA - parathyroid gland [nTPM]":"3.7","Tissue RNA - pituitary gland [nTPM]":"2.4","Tissue RNA - placenta [nTPM]":"17.0","Tissue RNA - pons [nTPM]":"2.6","Tissue RNA - prostate [nTPM]":"5.0","Tissue RNA - rectum [nTPM]":"10.2","Tissue RNA - retina [nTPM]":"3.5","Tissue RNA - salivary gland [nTPM]":"4.7","Tissue RNA - seminal vesicle [nTPM]":"2.8","Tissue RNA - skeletal muscle [nTPM]":"9.4","Tissue RNA - skin 1 [nTPM]":"10.6","Tissue RNA - small intestine [nTPM]":"8.6","Tissue RNA - smooth muscle [nTPM]":"5.3","Tissue RNA - spinal cord [nTPM]":"2.0","Tissue RNA - spleen [nTPM]":"9.6","Tissue RNA - stomach 1 [nTPM]":"5.7","Tissue RNA - testis [nTPM]":"12.3","Tissue RNA - thalamus [nTPM]":"2.0","Tissue RNA - thymus [nTPM]":"37.6","Tissue RNA - thyroid gland [nTPM]":"4.8","Tissue RNA - tongue [nTPM]":"5.8","Tissue RNA - tonsil [nTPM]":"26.0","Tissue RNA - urinary bladder [nTPM]":"4.2","Tissue RNA - vagina [nTPM]":"5.4","Tissue RNA - white matter [nTPM]":"2.4","Cell RNA - A-431 [nTPM]":"133.6","Cell RNA - A549 [nTPM]":"110.3","Cell RNA - AF22 [nTPM]":"122.4","Cell RNA - AN3-CA [nTPM]":"102.1","Cell RNA - ASC diff [nTPM]":"7.0","Cell RNA - ASC TERT1 [nTPM]":"14.4","Cell RNA - BEWO [nTPM]":"110.5","Cell RNA - BJ [nTPM]":"65.2","Cell RNA - BJ hTERT+ [nTPM]":"42.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"129.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"146.9","Cell RNA - CACO-2 [nTPM]":"177.7","Cell RNA - CAPAN-2 [nTPM]":"84.7","Cell RNA - Daudi [nTPM]":"136.0","Cell RNA - EFO-21 [nTPM]":"65.2","Cell RNA - fHDF\/TERT166 [nTPM]":"32.3","Cell RNA - GAMG [nTPM]":"113.6","Cell RNA - HaCaT [nTPM]":"105.6","Cell RNA - HAP1 [nTPM]":"204.8","Cell RNA - HBEC3-KT [nTPM]":"76.1","Cell RNA - HBF TERT88 [nTPM]":"79.1","Cell RNA - HDLM-2 [nTPM]":"127.2","Cell RNA - HEK 293 [nTPM]":"127.1","Cell RNA - HEL [nTPM]":"227.4","Cell RNA - HeLa [nTPM]":"134.8","Cell RNA - Hep G2 [nTPM]":"131.1","Cell RNA - HHSteC [nTPM]":"4.4","Cell RNA - HL-60 [nTPM]":"214.3","Cell RNA - HMC-1 [nTPM]":"102.4","Cell RNA - HSkMC [nTPM]":"8.2","Cell RNA - hTCEpi [nTPM]":"8.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"86.1","Cell RNA - hTERT-HME1 [nTPM]":"13.1","Cell RNA - hTERT-RPE1 [nTPM]":"15.3","Cell RNA - HUVEC TERT2 [nTPM]":"40.6","Cell RNA - JURKAT [nTPM]":"160.7","Cell RNA - K-562 [nTPM]":"116.0","Cell RNA - Karpas-707 [nTPM]":"123.7","Cell RNA - LHCN-M2 [nTPM]":"47.4","Cell RNA - MCF7 [nTPM]":"169.0","Cell RNA - MOLT-4 [nTPM]":"229.0","Cell RNA - NB-4 [nTPM]":"156.2","Cell RNA - NTERA-2 [nTPM]":"172.5","Cell RNA - OE19 [nTPM]":"108.3","Cell RNA - PC-3 [nTPM]":"90.7","Cell RNA - REH [nTPM]":"242.4","Cell RNA - RH-30 [nTPM]":"165.1","Cell RNA - RPMI-8226 [nTPM]":"203.3","Cell RNA - RPTEC TERT1 [nTPM]":"26.9","Cell RNA - RT4 [nTPM]":"97.9","Cell RNA - SCLC-21H [nTPM]":"143.0","Cell RNA - SH-SY5Y [nTPM]":"106.8","Cell RNA - SiHa [nTPM]":"175.8","Cell RNA - SK-BR-3 [nTPM]":"48.9","Cell RNA - SK-MEL-30 [nTPM]":"16.7","Cell RNA - SuSa [nTPM]":"45.7","Cell RNA - T-47d [nTPM]":"111.9","Cell RNA - THP-1 [nTPM]":"165.3","Cell RNA - TIME [nTPM]":"20.3","Cell RNA - U-138 MG [nTPM]":"104.2","Cell RNA - U-2 OS [nTPM]":"87.9","Cell RNA - U-2197 [nTPM]":"128.4","Cell RNA - U-251 MG [nTPM]":"91.7","Cell RNA - U-266\/70 [nTPM]":"127.1","Cell RNA - U-266\/84 [nTPM]":"163.5","Cell RNA - U-698 [nTPM]":"362.6","Cell RNA - U-87 MG [nTPM]":"73.2","Cell RNA - U-937 [nTPM]":"159.7","Cell RNA - WM-115 [nTPM]":"41.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"4.4","Blood RNA - intermediate monocyte [nTPM]":"1.4","Blood RNA - MAIT T-cell [nTPM]":"5.5","Blood RNA - memory B-cell [nTPM]":"9.7","Blood RNA - memory CD4 T-cell [nTPM]":"3.9","Blood RNA - memory CD8 T-cell [nTPM]":"5.4","Blood RNA - myeloid DC [nTPM]":"2.9","Blood RNA - naive B-cell [nTPM]":"8.1","Blood RNA - naive CD4 T-cell [nTPM]":"3.6","Blood RNA - naive CD8 T-cell [nTPM]":"4.7","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"6.5","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"3.7","Blood RNA - T-reg [nTPM]":"11.2","Blood RNA - total PBMC [nTPM]":"3.5","Brain RNA - amygdala [nTPM]":"2.0","Brain RNA - basal ganglia [nTPM]":"1.9","Brain RNA - cerebellum [nTPM]":"2.5","Brain RNA - cerebral cortex [nTPM]":"1.9","Brain RNA - hippocampal formation [nTPM]":"1.9","Brain RNA - hypothalamus [nTPM]":"1.8","Brain RNA - medulla oblongata [nTPM]":"2.3","Brain RNA - midbrain [nTPM]":"1.9","Brain RNA - pons [nTPM]":"2.6","Brain RNA - spinal cord [nTPM]":"2.0","Brain RNA - thalamus [nTPM]":"2.0","Brain RNA - white matter [nTPM]":"2.4","Single Cell Type RNA - Adipocytes [nTPM]":"1.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"8.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"2.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"63.3","Single Cell Type RNA - dendritic cells [nTPM]":"1.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.5","Single Cell Type RNA - Endothelial cells [nTPM]":"2.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"65.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"28.8","Single Cell Type RNA - Fibroblasts [nTPM]":"4.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.8","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"18.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"1.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"3.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"2.7","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"9.2","Single Cell Type RNA - Muller glia cells [nTPM]":"2.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.1","Single Cell Type RNA - Paneth cells [nTPM]":"1.7","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"20.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.1","Single Cell Type RNA - Spermatocytes [nTPM]":"8.1","Single Cell Type RNA - Spermatogonia [nTPM]":"25.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"33.5","Single Cell Type RNA - T-cells [nTPM]":"6.3","Single Cell Type RNA - Theca cells [nTPM]":"3.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.8","Single Cell Type RNA - Urothelial cells [nTPM]":"2.3"},{"Gene":"MCM3AP","Gene synonym":["GANP","KIAA0572","Map80","SAC3"],"Ensembl":"ENSG00000160294","Gene description":"Minichromosome maintenance complex component 3 associated protein","Uniprot":["O60318"],"Chromosome":"21","Position":"46235133-46286297","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Immunity","mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Mental retardation","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021527","HPA032103"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Nuclear membrane","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA021527":"AB_1853626","HPA032103":"AB_2674152"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.05e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Tissue RNA - adipose tissue [nTPM]":"16.8","Tissue RNA - adrenal gland [nTPM]":"12.0","Tissue RNA - amygdala [nTPM]":"10.0","Tissue RNA - appendix [nTPM]":"20.3","Tissue RNA - basal ganglia [nTPM]":"11.5","Tissue RNA - bone marrow [nTPM]":"19.7","Tissue RNA - breast [nTPM]":"13.6","Tissue RNA - cerebellum [nTPM]":"8.9","Tissue RNA - cerebral cortex [nTPM]":"10.7","Tissue RNA - cervix [nTPM]":"14.7","Tissue RNA - choroid plexus [nTPM]":"17.0","Tissue RNA - colon [nTPM]":"15.1","Tissue RNA - duodenum [nTPM]":"14.0","Tissue RNA - endometrium 1 [nTPM]":"16.5","Tissue RNA - epididymis [nTPM]":"8.3","Tissue RNA - esophagus [nTPM]":"14.3","Tissue RNA - fallopian tube [nTPM]":"15.2","Tissue RNA - gallbladder [nTPM]":"14.2","Tissue RNA - heart muscle [nTPM]":"15.1","Tissue RNA - hippocampal formation [nTPM]":"8.5","Tissue RNA - hypothalamus [nTPM]":"7.8","Tissue RNA - kidney [nTPM]":"13.0","Tissue RNA - liver [nTPM]":"9.7","Tissue RNA - lung [nTPM]":"16.0","Tissue RNA - lymph node [nTPM]":"21.0","Tissue RNA - medulla oblongata [nTPM]":"10.8","Tissue RNA - midbrain [nTPM]":"10.4","Tissue RNA - ovary [nTPM]":"17.6","Tissue RNA - pancreas [nTPM]":"15.4","Tissue RNA - parathyroid gland [nTPM]":"16.9","Tissue RNA - pituitary gland [nTPM]":"9.2","Tissue RNA - placenta [nTPM]":"16.3","Tissue RNA - pons [nTPM]":"9.5","Tissue RNA - prostate [nTPM]":"14.2","Tissue RNA - rectum [nTPM]":"15.0","Tissue RNA - retina [nTPM]":"12.8","Tissue RNA - salivary gland [nTPM]":"13.7","Tissue RNA - seminal vesicle [nTPM]":"13.4","Tissue RNA - skeletal muscle [nTPM]":"41.3","Tissue RNA - skin 1 [nTPM]":"13.8","Tissue RNA - small intestine [nTPM]":"16.1","Tissue RNA - smooth muscle [nTPM]":"17.1","Tissue RNA - spinal cord [nTPM]":"9.4","Tissue RNA - spleen [nTPM]":"19.6","Tissue RNA - stomach 1 [nTPM]":"15.4","Tissue RNA - testis [nTPM]":"14.1","Tissue RNA - thalamus [nTPM]":"11.0","Tissue RNA - thymus [nTPM]":"21.7","Tissue RNA - thyroid gland [nTPM]":"16.0","Tissue RNA - tongue [nTPM]":"28.7","Tissue RNA - tonsil [nTPM]":"21.5","Tissue RNA - urinary bladder [nTPM]":"13.6","Tissue RNA - vagina [nTPM]":"11.2","Tissue RNA - white matter [nTPM]":"14.6","Cell RNA - A-431 [nTPM]":"38.0","Cell RNA - A549 [nTPM]":"36.3","Cell RNA - AF22 [nTPM]":"41.8","Cell RNA - AN3-CA [nTPM]":"45.5","Cell RNA - ASC diff [nTPM]":"33.1","Cell RNA - ASC TERT1 [nTPM]":"41.4","Cell RNA - BEWO [nTPM]":"38.0","Cell RNA - BJ [nTPM]":"40.8","Cell RNA - BJ hTERT+ [nTPM]":"48.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"37.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"30.2","Cell RNA - CACO-2 [nTPM]":"33.1","Cell RNA - CAPAN-2 [nTPM]":"21.9","Cell RNA - Daudi [nTPM]":"53.6","Cell RNA - EFO-21 [nTPM]":"32.9","Cell RNA - fHDF\/TERT166 [nTPM]":"43.2","Cell RNA - GAMG [nTPM]":"40.3","Cell RNA - HaCaT [nTPM]":"21.9","Cell RNA - HAP1 [nTPM]":"55.9","Cell RNA - HBEC3-KT [nTPM]":"34.0","Cell RNA - HBF TERT88 [nTPM]":"32.7","Cell RNA - HDLM-2 [nTPM]":"55.7","Cell RNA - HEK 293 [nTPM]":"50.8","Cell RNA - HEL [nTPM]":"87.9","Cell RNA - HeLa [nTPM]":"35.0","Cell RNA - Hep G2 [nTPM]":"25.9","Cell RNA - HHSteC [nTPM]":"29.6","Cell RNA - HL-60 [nTPM]":"40.6","Cell RNA - HMC-1 [nTPM]":"47.7","Cell RNA - HSkMC [nTPM]":"31.7","Cell RNA - hTCEpi [nTPM]":"28.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"51.2","Cell RNA - hTERT-HME1 [nTPM]":"35.2","Cell RNA - hTERT-RPE1 [nTPM]":"25.4","Cell RNA - HUVEC TERT2 [nTPM]":"40.7","Cell RNA - JURKAT [nTPM]":"31.7","Cell RNA - K-562 [nTPM]":"107.3","Cell RNA - Karpas-707 [nTPM]":"39.6","Cell RNA - LHCN-M2 [nTPM]":"43.3","Cell RNA - MCF7 [nTPM]":"21.1","Cell RNA - MOLT-4 [nTPM]":"43.5","Cell RNA - NB-4 [nTPM]":"26.8","Cell RNA - NTERA-2 [nTPM]":"72.3","Cell RNA - OE19 [nTPM]":"40.0","Cell RNA - PC-3 [nTPM]":"30.2","Cell RNA - REH [nTPM]":"56.3","Cell RNA - RH-30 [nTPM]":"26.6","Cell RNA - RPMI-8226 [nTPM]":"48.9","Cell RNA - RPTEC TERT1 [nTPM]":"17.8","Cell RNA - RT4 [nTPM]":"34.1","Cell RNA - SCLC-21H [nTPM]":"35.2","Cell RNA - SH-SY5Y [nTPM]":"37.6","Cell RNA - SiHa [nTPM]":"52.4","Cell RNA - SK-BR-3 [nTPM]":"33.7","Cell RNA - SK-MEL-30 [nTPM]":"39.0","Cell RNA - SuSa [nTPM]":"31.5","Cell RNA - T-47d [nTPM]":"46.0","Cell RNA - THP-1 [nTPM]":"41.2","Cell RNA - TIME [nTPM]":"51.6","Cell RNA - U-138 MG [nTPM]":"39.1","Cell RNA - U-2 OS [nTPM]":"29.7","Cell RNA - U-2197 [nTPM]":"33.1","Cell RNA - U-251 MG [nTPM]":"31.0","Cell RNA - U-266\/70 [nTPM]":"71.8","Cell RNA - U-266\/84 [nTPM]":"86.2","Cell RNA - U-698 [nTPM]":"33.0","Cell RNA - U-87 MG [nTPM]":"35.3","Cell RNA - U-937 [nTPM]":"38.0","Cell RNA - WM-115 [nTPM]":"51.8","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"2.0","Blood RNA - eosinophil [nTPM]":"1.6","Blood RNA - gdT-cell [nTPM]":"2.3","Blood RNA - intermediate monocyte [nTPM]":"1.9","Blood RNA - MAIT T-cell [nTPM]":"2.4","Blood RNA - memory B-cell [nTPM]":"1.1","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"2.6","Blood RNA - myeloid DC [nTPM]":"1.9","Blood RNA - naive B-cell [nTPM]":"1.6","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"1.3","Blood RNA - neutrophil [nTPM]":"1.2","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"1.1","Blood RNA - plasmacytoid DC [nTPM]":"1.6","Blood RNA - T-reg [nTPM]":"1.8","Blood RNA - total PBMC [nTPM]":"2.1","Brain RNA - amygdala [nTPM]":"10.0","Brain RNA - basal ganglia [nTPM]":"11.5","Brain RNA - cerebellum [nTPM]":"8.9","Brain RNA - cerebral cortex [nTPM]":"10.7","Brain RNA - hippocampal formation [nTPM]":"8.5","Brain RNA - hypothalamus [nTPM]":"7.8","Brain RNA - medulla oblongata [nTPM]":"10.8","Brain RNA - midbrain [nTPM]":"10.4","Brain RNA - pons [nTPM]":"9.5","Brain RNA - spinal cord [nTPM]":"9.4","Brain RNA - thalamus [nTPM]":"11.0","Brain RNA - white matter [nTPM]":"14.6","Single Cell Type RNA - Adipocytes [nTPM]":"17.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.9","Single Cell Type RNA - Astrocytes [nTPM]":"28.1","Single Cell Type RNA - B-cells [nTPM]":"21.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.2","Single Cell Type RNA - Bipolar cells [nTPM]":"21.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"12.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.4","Single Cell Type RNA - dendritic cells [nTPM]":"20.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.3","Single Cell Type RNA - Early spermatids [nTPM]":"3.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.7","Single Cell Type RNA - Endothelial cells [nTPM]":"14.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.0","Single Cell Type RNA - Erythroid cells [nTPM]":"18.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"28.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.7","Single Cell Type RNA - Fibroblasts [nTPM]":"12.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"27.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.7","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"20.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"18.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.4","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"34.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.2","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"19.7","Single Cell Type RNA - Langerhans cells [nTPM]":"8.4","Single Cell Type RNA - Late spermatids [nTPM]":"4.3","Single Cell Type RNA - Leydig cells [nTPM]":"18.3","Single Cell Type RNA - Macrophages [nTPM]":"18.6","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"34.7","Single Cell Type RNA - monocytes [nTPM]":"24.3","Single Cell Type RNA - Muller glia cells [nTPM]":"9.3","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"37.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"35.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.9","Single Cell Type RNA - Paneth cells [nTPM]":"8.6","Single Cell Type RNA - Peritubular cells [nTPM]":"14.3","Single Cell Type RNA - Plasma cells [nTPM]":"21.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.7","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.9","Single Cell Type RNA - Spermatocytes [nTPM]":"19.7","Single Cell Type RNA - Spermatogonia [nTPM]":"15.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.3","Single Cell Type RNA - T-cells [nTPM]":"19.1","Single Cell Type RNA - Theca cells [nTPM]":"16.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.9","Single Cell Type RNA - Urothelial cells [nTPM]":"7.9"},{"Gene":"MCM4","Gene synonym":["CDC21","CDC54","hCdc21","MGC33310","P1-Cdc21"],"Ensembl":"ENSG00000104738","Gene description":"Minichromosome maintenance complex component 4","Uniprot":["P33991"],"Chromosome":"8","Position":"47960185-47978160","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA replication"],"Molecular function":["DNA-binding","Helicase","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"63.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"153.2","Erythroid cells":"60.8","Late spermatids":"77.9","Spermatocytes":"65.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004497","HPA004873","HPA031052"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"140000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB004497":"AB_627916","HPA004873":"AB_1079337","HPA031052":"AB_2673712"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.19e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.84e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.23e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.15e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.38e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.61e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.5","Tissue RNA - adrenal gland [nTPM]":"8.8","Tissue RNA - amygdala [nTPM]":"4.8","Tissue RNA - appendix [nTPM]":"21.7","Tissue RNA - basal ganglia [nTPM]":"4.8","Tissue RNA - bone marrow [nTPM]":"63.2","Tissue RNA - breast [nTPM]":"16.0","Tissue RNA - cerebellum [nTPM]":"5.7","Tissue RNA - cerebral cortex [nTPM]":"5.2","Tissue RNA - cervix [nTPM]":"7.7","Tissue RNA - choroid plexus [nTPM]":"1.8","Tissue RNA - colon [nTPM]":"17.7","Tissue RNA - duodenum [nTPM]":"13.3","Tissue RNA - endometrium 1 [nTPM]":"6.9","Tissue RNA - epididymis [nTPM]":"4.6","Tissue RNA - esophagus [nTPM]":"22.4","Tissue RNA - fallopian tube [nTPM]":"9.7","Tissue RNA - gallbladder [nTPM]":"5.6","Tissue RNA - heart muscle [nTPM]":"14.5","Tissue RNA - hippocampal formation [nTPM]":"5.2","Tissue RNA - hypothalamus [nTPM]":"3.5","Tissue RNA - kidney [nTPM]":"8.2","Tissue RNA - liver [nTPM]":"9.2","Tissue RNA - lung [nTPM]":"6.3","Tissue RNA - lymph node [nTPM]":"38.7","Tissue RNA - medulla oblongata [nTPM]":"3.6","Tissue RNA - midbrain [nTPM]":"4.2","Tissue RNA - ovary [nTPM]":"7.1","Tissue RNA - pancreas [nTPM]":"5.5","Tissue RNA - parathyroid gland [nTPM]":"7.7","Tissue RNA - pituitary gland [nTPM]":"4.1","Tissue RNA - placenta [nTPM]":"18.3","Tissue RNA - pons [nTPM]":"3.9","Tissue RNA - prostate [nTPM]":"5.6","Tissue RNA - rectum [nTPM]":"21.3","Tissue RNA - retina [nTPM]":"12.3","Tissue RNA - salivary gland [nTPM]":"8.8","Tissue RNA - seminal vesicle [nTPM]":"4.9","Tissue RNA - skeletal muscle [nTPM]":"13.4","Tissue RNA - skin 1 [nTPM]":"24.2","Tissue RNA - small intestine [nTPM]":"16.7","Tissue RNA - smooth muscle [nTPM]":"9.2","Tissue RNA - spinal cord [nTPM]":"4.2","Tissue RNA - spleen [nTPM]":"8.1","Tissue RNA - stomach 1 [nTPM]":"10.6","Tissue RNA - testis [nTPM]":"41.6","Tissue RNA - thalamus [nTPM]":"4.8","Tissue RNA - thymus [nTPM]":"47.0","Tissue RNA - thyroid gland [nTPM]":"6.5","Tissue RNA - tongue [nTPM]":"15.8","Tissue RNA - tonsil [nTPM]":"41.8","Tissue RNA - urinary bladder [nTPM]":"11.8","Tissue RNA - vagina [nTPM]":"10.9","Tissue RNA - white matter [nTPM]":"5.2","Cell RNA - A-431 [nTPM]":"184.0","Cell RNA - A549 [nTPM]":"139.6","Cell RNA - AF22 [nTPM]":"188.1","Cell RNA - AN3-CA [nTPM]":"83.2","Cell RNA - ASC diff [nTPM]":"20.7","Cell RNA - ASC TERT1 [nTPM]":"36.6","Cell RNA - BEWO [nTPM]":"102.8","Cell RNA - BJ [nTPM]":"122.6","Cell RNA - BJ hTERT+ [nTPM]":"99.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"178.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"190.3","Cell RNA - CACO-2 [nTPM]":"156.6","Cell RNA - CAPAN-2 [nTPM]":"181.1","Cell RNA - Daudi [nTPM]":"229.8","Cell RNA - EFO-21 [nTPM]":"70.3","Cell RNA - fHDF\/TERT166 [nTPM]":"72.1","Cell RNA - GAMG [nTPM]":"119.2","Cell RNA - HaCaT [nTPM]":"143.2","Cell RNA - HAP1 [nTPM]":"278.7","Cell RNA - HBEC3-KT [nTPM]":"128.2","Cell RNA - HBF TERT88 [nTPM]":"199.8","Cell RNA - HDLM-2 [nTPM]":"64.2","Cell RNA - HEK 293 [nTPM]":"190.4","Cell RNA - HEL [nTPM]":"371.8","Cell RNA - HeLa [nTPM]":"133.3","Cell RNA - Hep G2 [nTPM]":"169.2","Cell RNA - HHSteC [nTPM]":"5.4","Cell RNA - HL-60 [nTPM]":"189.7","Cell RNA - HMC-1 [nTPM]":"82.0","Cell RNA - HSkMC [nTPM]":"20.3","Cell RNA - hTCEpi [nTPM]":"24.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"147.8","Cell RNA - hTERT-HME1 [nTPM]":"54.3","Cell RNA - hTERT-RPE1 [nTPM]":"28.6","Cell RNA - HUVEC TERT2 [nTPM]":"72.0","Cell RNA - JURKAT [nTPM]":"136.8","Cell RNA - K-562 [nTPM]":"216.2","Cell RNA - Karpas-707 [nTPM]":"167.0","Cell RNA - LHCN-M2 [nTPM]":"129.9","Cell RNA - MCF7 [nTPM]":"155.6","Cell RNA - MOLT-4 [nTPM]":"435.5","Cell RNA - NB-4 [nTPM]":"141.5","Cell RNA - NTERA-2 [nTPM]":"241.2","Cell RNA - OE19 [nTPM]":"246.5","Cell RNA - PC-3 [nTPM]":"54.2","Cell RNA - REH [nTPM]":"266.6","Cell RNA - RH-30 [nTPM]":"159.6","Cell RNA - RPMI-8226 [nTPM]":"139.2","Cell RNA - RPTEC TERT1 [nTPM]":"64.9","Cell RNA - RT4 [nTPM]":"168.1","Cell RNA - SCLC-21H [nTPM]":"209.0","Cell RNA - SH-SY5Y [nTPM]":"97.8","Cell RNA - SiHa [nTPM]":"325.6","Cell RNA - SK-BR-3 [nTPM]":"133.6","Cell RNA - SK-MEL-30 [nTPM]":"46.3","Cell RNA - SuSa [nTPM]":"117.7","Cell RNA - T-47d [nTPM]":"154.9","Cell RNA - THP-1 [nTPM]":"110.5","Cell RNA - TIME [nTPM]":"45.1","Cell RNA - U-138 MG [nTPM]":"138.1","Cell RNA - U-2 OS [nTPM]":"125.4","Cell RNA - U-2197 [nTPM]":"144.5","Cell RNA - U-251 MG [nTPM]":"131.9","Cell RNA - U-266\/70 [nTPM]":"54.7","Cell RNA - U-266\/84 [nTPM]":"104.6","Cell RNA - U-698 [nTPM]":"347.2","Cell RNA - U-87 MG [nTPM]":"114.8","Cell RNA - U-937 [nTPM]":"185.7","Cell RNA - WM-115 [nTPM]":"131.5","Blood RNA - basophil [nTPM]":"2.3","Blood RNA - classical monocyte [nTPM]":"1.8","Blood RNA - eosinophil [nTPM]":"1.1","Blood RNA - gdT-cell [nTPM]":"4.0","Blood RNA - intermediate monocyte [nTPM]":"3.1","Blood RNA - MAIT T-cell [nTPM]":"2.0","Blood RNA - memory B-cell [nTPM]":"3.9","Blood RNA - memory CD4 T-cell [nTPM]":"3.8","Blood RNA - memory CD8 T-cell [nTPM]":"5.4","Blood RNA - myeloid DC [nTPM]":"3.9","Blood RNA - naive B-cell [nTPM]":"1.6","Blood RNA - naive CD4 T-cell [nTPM]":"3.3","Blood RNA - naive CD8 T-cell [nTPM]":"2.7","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"4.1","Blood RNA - non-classical monocyte [nTPM]":"3.5","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"10.2","Blood RNA - total PBMC [nTPM]":"3.6","Brain RNA - amygdala [nTPM]":"4.8","Brain RNA - basal ganglia [nTPM]":"4.8","Brain RNA - cerebellum [nTPM]":"5.7","Brain RNA - cerebral cortex [nTPM]":"5.2","Brain RNA - hippocampal formation [nTPM]":"5.2","Brain RNA - hypothalamus [nTPM]":"3.5","Brain RNA - medulla oblongata [nTPM]":"3.6","Brain RNA - midbrain [nTPM]":"4.2","Brain RNA - pons [nTPM]":"3.9","Brain RNA - spinal cord [nTPM]":"4.2","Brain RNA - thalamus [nTPM]":"4.8","Brain RNA - white matter [nTPM]":"5.2","Single Cell Type RNA - Adipocytes [nTPM]":"3.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.3","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"6.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"21.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"12.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"8.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"36.7","Single Cell Type RNA - dendritic cells [nTPM]":"5.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.0","Single Cell Type RNA - Early spermatids [nTPM]":"153.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.9","Single Cell Type RNA - Endothelial cells [nTPM]":"6.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"60.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"40.2","Single Cell Type RNA - Fibroblasts [nTPM]":"10.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.4","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"24.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"3.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.3","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.9","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"2.9","Single Cell Type RNA - Langerhans cells [nTPM]":"6.5","Single Cell Type RNA - Late spermatids [nTPM]":"77.9","Single Cell Type RNA - Leydig cells [nTPM]":"5.3","Single Cell Type RNA - Macrophages [nTPM]":"7.9","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"2.4","Single Cell Type RNA - Muller glia cells [nTPM]":"7.0","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.5","Single Cell Type RNA - Paneth cells [nTPM]":"4.8","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"22.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.4","Single Cell Type RNA - Spermatocytes [nTPM]":"65.8","Single Cell Type RNA - Spermatogonia [nTPM]":"39.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"19.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"29.8","Single Cell Type RNA - T-cells [nTPM]":"9.0","Single Cell Type RNA - Theca cells [nTPM]":"11.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.2","Single Cell Type RNA - Urothelial cells [nTPM]":"9.7"},{"Gene":"MCM5","Gene synonym":["CDC46"],"Ensembl":"ENSG00000100297","Gene description":"Minichromosome maintenance complex component 5","Uniprot":["P33992"],"Chromosome":"22","Position":"35400134-35425431","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA replication"],"Molecular function":["DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"138.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"147.8","Erythroid cells":"96.6","monocytes":"137.7","Syncytiotrophoblasts":"82.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000101","HPA000845","HPA052880"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"44000","Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB000101":"AB_2235163","HPA000845":"AB_1079338","HPA052880":"AB_2681979"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.81e-6"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.78e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.95e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.58e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Tissue RNA - adipose tissue [nTPM]":"15.2","Tissue RNA - adrenal gland [nTPM]":"7.1","Tissue RNA - amygdala [nTPM]":"5.8","Tissue RNA - appendix [nTPM]":"49.1","Tissue RNA - basal ganglia [nTPM]":"10.4","Tissue RNA - bone marrow [nTPM]":"138.7","Tissue RNA - breast [nTPM]":"14.4","Tissue RNA - cerebellum [nTPM]":"8.3","Tissue RNA - cerebral cortex [nTPM]":"7.4","Tissue RNA - cervix [nTPM]":"14.5","Tissue RNA - choroid plexus [nTPM]":"5.8","Tissue RNA - colon [nTPM]":"20.2","Tissue RNA - duodenum [nTPM]":"19.6","Tissue RNA - endometrium 1 [nTPM]":"16.3","Tissue RNA - epididymis [nTPM]":"3.3","Tissue RNA - esophagus [nTPM]":"25.1","Tissue RNA - fallopian tube [nTPM]":"13.7","Tissue RNA - gallbladder [nTPM]":"9.6","Tissue RNA - heart muscle [nTPM]":"8.9","Tissue RNA - hippocampal formation [nTPM]":"5.8","Tissue RNA - hypothalamus [nTPM]":"7.0","Tissue RNA - kidney [nTPM]":"9.1","Tissue RNA - liver [nTPM]":"14.9","Tissue RNA - lung [nTPM]":"14.8","Tissue RNA - lymph node [nTPM]":"70.1","Tissue RNA - medulla oblongata [nTPM]":"10.3","Tissue RNA - midbrain [nTPM]":"7.7","Tissue RNA - ovary [nTPM]":"25.6","Tissue RNA - pancreas [nTPM]":"12.6","Tissue RNA - parathyroid gland [nTPM]":"10.3","Tissue RNA - pituitary gland [nTPM]":"5.3","Tissue RNA - placenta [nTPM]":"25.2","Tissue RNA - pons [nTPM]":"9.6","Tissue RNA - prostate [nTPM]":"10.2","Tissue RNA - rectum [nTPM]":"16.7","Tissue RNA - retina [nTPM]":"2.3","Tissue RNA - salivary gland [nTPM]":"13.9","Tissue RNA - seminal vesicle [nTPM]":"9.6","Tissue RNA - skeletal muscle [nTPM]":"13.3","Tissue RNA - skin 1 [nTPM]":"17.6","Tissue RNA - small intestine [nTPM]":"28.3","Tissue RNA - smooth muscle [nTPM]":"12.2","Tissue RNA - spinal cord [nTPM]":"8.1","Tissue RNA - spleen [nTPM]":"47.3","Tissue RNA - stomach 1 [nTPM]":"17.9","Tissue RNA - testis [nTPM]":"20.6","Tissue RNA - thalamus [nTPM]":"9.0","Tissue RNA - thymus [nTPM]":"58.9","Tissue RNA - thyroid gland [nTPM]":"12.1","Tissue RNA - tongue [nTPM]":"8.0","Tissue RNA - tonsil [nTPM]":"53.6","Tissue RNA - urinary bladder [nTPM]":"12.7","Tissue RNA - vagina [nTPM]":"15.6","Tissue RNA - white matter [nTPM]":"12.3","Cell RNA - A-431 [nTPM]":"213.0","Cell RNA - A549 [nTPM]":"147.5","Cell RNA - AF22 [nTPM]":"115.7","Cell RNA - AN3-CA [nTPM]":"118.8","Cell RNA - ASC diff [nTPM]":"11.0","Cell RNA - ASC TERT1 [nTPM]":"22.2","Cell RNA - BEWO [nTPM]":"100.6","Cell RNA - BJ [nTPM]":"138.1","Cell RNA - BJ hTERT+ [nTPM]":"71.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"199.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"188.3","Cell RNA - CACO-2 [nTPM]":"98.9","Cell RNA - CAPAN-2 [nTPM]":"102.4","Cell RNA - Daudi [nTPM]":"137.9","Cell RNA - EFO-21 [nTPM]":"78.8","Cell RNA - fHDF\/TERT166 [nTPM]":"70.5","Cell RNA - GAMG [nTPM]":"83.6","Cell RNA - HaCaT [nTPM]":"103.8","Cell RNA - HAP1 [nTPM]":"116.0","Cell RNA - HBEC3-KT [nTPM]":"108.3","Cell RNA - HBF TERT88 [nTPM]":"64.4","Cell RNA - HDLM-2 [nTPM]":"112.7","Cell RNA - HEK 293 [nTPM]":"212.6","Cell RNA - HEL [nTPM]":"198.3","Cell RNA - HeLa [nTPM]":"141.5","Cell RNA - Hep G2 [nTPM]":"203.7","Cell RNA - HHSteC [nTPM]":"3.9","Cell RNA - HL-60 [nTPM]":"414.0","Cell RNA - HMC-1 [nTPM]":"172.4","Cell RNA - HSkMC [nTPM]":"12.3","Cell RNA - hTCEpi [nTPM]":"9.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"120.0","Cell RNA - hTERT-HME1 [nTPM]":"32.4","Cell RNA - hTERT-RPE1 [nTPM]":"18.4","Cell RNA - HUVEC TERT2 [nTPM]":"88.7","Cell RNA - JURKAT [nTPM]":"124.5","Cell RNA - K-562 [nTPM]":"124.0","Cell RNA - Karpas-707 [nTPM]":"201.2","Cell RNA - LHCN-M2 [nTPM]":"76.9","Cell RNA - MCF7 [nTPM]":"172.7","Cell RNA - MOLT-4 [nTPM]":"341.8","Cell RNA - NB-4 [nTPM]":"137.9","Cell RNA - NTERA-2 [nTPM]":"154.9","Cell RNA - OE19 [nTPM]":"143.4","Cell RNA - PC-3 [nTPM]":"86.7","Cell RNA - REH [nTPM]":"379.6","Cell RNA - RH-30 [nTPM]":"164.8","Cell RNA - RPMI-8226 [nTPM]":"173.0","Cell RNA - RPTEC TERT1 [nTPM]":"39.4","Cell RNA - RT4 [nTPM]":"120.1","Cell RNA - SCLC-21H [nTPM]":"88.2","Cell RNA - SH-SY5Y [nTPM]":"94.8","Cell RNA - SiHa [nTPM]":"188.3","Cell RNA - SK-BR-3 [nTPM]":"75.4","Cell RNA - SK-MEL-30 [nTPM]":"41.8","Cell RNA - SuSa [nTPM]":"60.9","Cell RNA - T-47d [nTPM]":"78.8","Cell RNA - THP-1 [nTPM]":"155.6","Cell RNA - TIME [nTPM]":"54.1","Cell RNA - U-138 MG [nTPM]":"201.3","Cell RNA - U-2 OS [nTPM]":"153.1","Cell RNA - U-2197 [nTPM]":"127.2","Cell RNA - U-251 MG [nTPM]":"145.4","Cell RNA - U-266\/70 [nTPM]":"111.9","Cell RNA - U-266\/84 [nTPM]":"150.2","Cell RNA - U-698 [nTPM]":"265.2","Cell RNA - U-87 MG [nTPM]":"130.9","Cell RNA - U-937 [nTPM]":"153.5","Cell RNA - WM-115 [nTPM]":"157.6","Blood RNA - basophil [nTPM]":"66.5","Blood RNA - classical monocyte [nTPM]":"59.8","Blood RNA - eosinophil [nTPM]":"43.4","Blood RNA - gdT-cell [nTPM]":"49.5","Blood RNA - intermediate monocyte [nTPM]":"69.6","Blood RNA - MAIT T-cell [nTPM]":"35.8","Blood RNA - memory B-cell [nTPM]":"127.5","Blood RNA - memory CD4 T-cell [nTPM]":"43.1","Blood RNA - memory CD8 T-cell [nTPM]":"53.1","Blood RNA - myeloid DC [nTPM]":"77.8","Blood RNA - naive B-cell [nTPM]":"106.1","Blood RNA - naive CD4 T-cell [nTPM]":"34.0","Blood RNA - naive CD8 T-cell [nTPM]":"39.0","Blood RNA - neutrophil [nTPM]":"28.4","Blood RNA - NK-cell [nTPM]":"65.5","Blood RNA - non-classical monocyte [nTPM]":"81.2","Blood RNA - plasmacytoid DC [nTPM]":"88.8","Blood RNA - T-reg [nTPM]":"96.6","Blood RNA - total PBMC [nTPM]":"77.1","Brain RNA - amygdala [nTPM]":"5.8","Brain RNA - basal ganglia [nTPM]":"10.4","Brain RNA - cerebellum [nTPM]":"8.3","Brain RNA - cerebral cortex [nTPM]":"7.4","Brain RNA - hippocampal formation [nTPM]":"5.8","Brain RNA - hypothalamus [nTPM]":"7.0","Brain RNA - medulla oblongata [nTPM]":"10.3","Brain RNA - midbrain [nTPM]":"7.7","Brain RNA - pons [nTPM]":"9.6","Brain RNA - spinal cord [nTPM]":"8.1","Brain RNA - thalamus [nTPM]":"9.0","Brain RNA - white matter [nTPM]":"12.3","Single Cell Type RNA - Adipocytes [nTPM]":"8.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.3","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"49.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"6.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"147.8","Single Cell Type RNA - dendritic cells [nTPM]":"30.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"19.8","Single Cell Type RNA - Early spermatids [nTPM]":"2.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.1","Single Cell Type RNA - Endothelial cells [nTPM]":"11.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.5","Single Cell Type RNA - Erythroid cells [nTPM]":"96.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"77.1","Single Cell Type RNA - Fibroblasts [nTPM]":"11.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.0","Single Cell Type RNA - granulocytes [nTPM]":"15.2","Single Cell Type RNA - Granulosa cells [nTPM]":"65.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.2","Single Cell Type RNA - Hepatocytes [nTPM]":"5.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"53.1","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.6","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"24.0","Single Cell Type RNA - Langerhans cells [nTPM]":"29.4","Single Cell Type RNA - Late spermatids [nTPM]":"5.1","Single Cell Type RNA - Leydig cells [nTPM]":"10.8","Single Cell Type RNA - Macrophages [nTPM]":"28.4","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"137.7","Single Cell Type RNA - Muller glia cells [nTPM]":"5.7","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.0","Single Cell Type RNA - Paneth cells [nTPM]":"8.6","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"49.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.7","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.5","Single Cell Type RNA - Spermatocytes [nTPM]":"16.1","Single Cell Type RNA - Spermatogonia [nTPM]":"58.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"82.2","Single Cell Type RNA - T-cells [nTPM]":"19.4","Single Cell Type RNA - Theca cells [nTPM]":"8.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"34.6","Single Cell Type RNA - Urothelial cells [nTPM]":"9.8"},{"Gene":"MCM8","Gene synonym":["C20orf154","dJ967N21.5","MGC119522","MGC119523","MGC12866","MGC4816","REC"],"Ensembl":"ENSG00000125885","Gene description":"Minichromosome maintenance 8 homologous recombination repair factor","Uniprot":["Q9UJA3"],"Chromosome":"20","Position":"5950652-5998977","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA damage","DNA repair","DNA replication"],"Molecular function":["DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Disease variant","Premature ovarian failure"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"71.8","Spermatogonia":"37.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045141","HPA066433"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA045141":"AB_2679230","HPA066433":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.30e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.50e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-1"},"Tissue RNA - adipose tissue [nTPM]":"2.9","Tissue RNA - adrenal gland [nTPM]":"2.9","Tissue RNA - amygdala [nTPM]":"3.0","Tissue RNA - appendix [nTPM]":"4.6","Tissue RNA - basal ganglia [nTPM]":"4.1","Tissue RNA - bone marrow [nTPM]":"10.2","Tissue RNA - breast [nTPM]":"2.8","Tissue RNA - cerebellum [nTPM]":"6.8","Tissue RNA - cerebral cortex [nTPM]":"4.4","Tissue RNA - cervix [nTPM]":"4.0","Tissue RNA - choroid plexus [nTPM]":"4.2","Tissue RNA - colon [nTPM]":"3.9","Tissue RNA - duodenum [nTPM]":"3.6","Tissue RNA - endometrium 1 [nTPM]":"3.1","Tissue RNA - epididymis [nTPM]":"2.1","Tissue RNA - esophagus [nTPM]":"3.7","Tissue RNA - fallopian tube [nTPM]":"3.2","Tissue RNA - gallbladder [nTPM]":"1.7","Tissue RNA - heart muscle [nTPM]":"3.3","Tissue RNA - hippocampal formation [nTPM]":"3.1","Tissue RNA - hypothalamus [nTPM]":"3.4","Tissue RNA - kidney [nTPM]":"2.4","Tissue RNA - liver [nTPM]":"1.8","Tissue RNA - lung [nTPM]":"2.4","Tissue RNA - lymph node [nTPM]":"7.5","Tissue RNA - medulla oblongata [nTPM]":"2.9","Tissue RNA - midbrain [nTPM]":"3.1","Tissue RNA - ovary [nTPM]":"2.6","Tissue RNA - pancreas [nTPM]":"3.1","Tissue RNA - parathyroid gland [nTPM]":"2.0","Tissue RNA - pituitary gland [nTPM]":"1.6","Tissue RNA - placenta [nTPM]":"3.3","Tissue RNA - pons [nTPM]":"3.1","Tissue RNA - prostate [nTPM]":"3.6","Tissue RNA - rectum [nTPM]":"3.2","Tissue RNA - retina [nTPM]":"5.3","Tissue RNA - salivary gland [nTPM]":"2.9","Tissue RNA - seminal vesicle [nTPM]":"1.8","Tissue RNA - skeletal muscle [nTPM]":"6.9","Tissue RNA - skin 1 [nTPM]":"4.7","Tissue RNA - small intestine [nTPM]":"3.7","Tissue RNA - smooth muscle [nTPM]":"2.1","Tissue RNA - spinal cord [nTPM]":"2.6","Tissue RNA - spleen [nTPM]":"3.6","Tissue RNA - stomach 1 [nTPM]":"3.3","Tissue RNA - testis [nTPM]":"13.4","Tissue RNA - thalamus [nTPM]":"3.1","Tissue RNA - thymus [nTPM]":"9.0","Tissue RNA - thyroid gland [nTPM]":"2.4","Tissue RNA - tongue [nTPM]":"4.6","Tissue RNA - tonsil [nTPM]":"6.5","Tissue RNA - urinary bladder [nTPM]":"3.4","Tissue RNA - vagina [nTPM]":"3.6","Tissue RNA - white matter [nTPM]":"5.8","Cell RNA - A-431 [nTPM]":"48.6","Cell RNA - A549 [nTPM]":"33.0","Cell RNA - AF22 [nTPM]":"27.7","Cell RNA - AN3-CA [nTPM]":"30.3","Cell RNA - ASC diff [nTPM]":"4.6","Cell RNA - ASC TERT1 [nTPM]":"6.6","Cell RNA - BEWO [nTPM]":"27.4","Cell RNA - BJ [nTPM]":"38.1","Cell RNA - BJ hTERT+ [nTPM]":"12.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"26.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"32.0","Cell RNA - CACO-2 [nTPM]":"35.4","Cell RNA - CAPAN-2 [nTPM]":"27.6","Cell RNA - Daudi [nTPM]":"48.3","Cell RNA - EFO-21 [nTPM]":"11.3","Cell RNA - fHDF\/TERT166 [nTPM]":"10.2","Cell RNA - GAMG [nTPM]":"51.5","Cell RNA - HaCaT [nTPM]":"50.9","Cell RNA - HAP1 [nTPM]":"46.1","Cell RNA - HBEC3-KT [nTPM]":"25.7","Cell RNA - HBF TERT88 [nTPM]":"47.9","Cell RNA - HDLM-2 [nTPM]":"13.4","Cell RNA - HEK 293 [nTPM]":"21.5","Cell RNA - HEL [nTPM]":"49.3","Cell RNA - HeLa [nTPM]":"16.8","Cell RNA - Hep G2 [nTPM]":"27.9","Cell RNA - HHSteC [nTPM]":"0.9","Cell RNA - HL-60 [nTPM]":"56.6","Cell RNA - HMC-1 [nTPM]":"7.4","Cell RNA - HSkMC [nTPM]":"2.5","Cell RNA - hTCEpi [nTPM]":"3.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"47.2","Cell RNA - hTERT-HME1 [nTPM]":"17.6","Cell RNA - hTERT-RPE1 [nTPM]":"5.3","Cell RNA - HUVEC TERT2 [nTPM]":"12.3","Cell RNA - JURKAT [nTPM]":"28.7","Cell RNA - K-562 [nTPM]":"56.7","Cell RNA - Karpas-707 [nTPM]":"45.8","Cell RNA - LHCN-M2 [nTPM]":"27.1","Cell RNA - MCF7 [nTPM]":"12.3","Cell RNA - MOLT-4 [nTPM]":"27.6","Cell RNA - NB-4 [nTPM]":"30.0","Cell RNA - NTERA-2 [nTPM]":"40.3","Cell RNA - OE19 [nTPM]":"25.3","Cell RNA - PC-3 [nTPM]":"21.6","Cell RNA - REH [nTPM]":"34.8","Cell RNA - RH-30 [nTPM]":"50.9","Cell RNA - RPMI-8226 [nTPM]":"18.6","Cell RNA - RPTEC TERT1 [nTPM]":"5.0","Cell RNA - RT4 [nTPM]":"15.3","Cell RNA - SCLC-21H [nTPM]":"21.6","Cell RNA - SH-SY5Y [nTPM]":"23.2","Cell RNA - SiHa [nTPM]":"40.0","Cell RNA - SK-BR-3 [nTPM]":"36.3","Cell RNA - SK-MEL-30 [nTPM]":"22.5","Cell RNA - SuSa [nTPM]":"28.6","Cell RNA - T-47d [nTPM]":"27.1","Cell RNA - THP-1 [nTPM]":"16.4","Cell RNA - TIME [nTPM]":"9.6","Cell RNA - U-138 MG [nTPM]":"51.5","Cell RNA - U-2 OS [nTPM]":"43.2","Cell RNA - U-2197 [nTPM]":"28.2","Cell RNA - U-251 MG [nTPM]":"56.8","Cell RNA - U-266\/70 [nTPM]":"20.1","Cell RNA - U-266\/84 [nTPM]":"53.8","Cell RNA - U-698 [nTPM]":"82.2","Cell RNA - U-87 MG [nTPM]":"9.6","Cell RNA - U-937 [nTPM]":"33.5","Cell RNA - WM-115 [nTPM]":"43.4","Blood RNA - basophil [nTPM]":"1.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.5","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"3.0","Brain RNA - basal ganglia [nTPM]":"4.1","Brain RNA - cerebellum [nTPM]":"6.8","Brain RNA - cerebral cortex [nTPM]":"4.4","Brain RNA - hippocampal formation [nTPM]":"3.1","Brain RNA - hypothalamus [nTPM]":"3.4","Brain RNA - medulla oblongata [nTPM]":"2.9","Brain RNA - midbrain [nTPM]":"3.1","Brain RNA - pons [nTPM]":"3.1","Brain RNA - spinal cord [nTPM]":"2.6","Brain RNA - thalamus [nTPM]":"3.1","Brain RNA - white matter [nTPM]":"5.8","Single Cell Type RNA - Adipocytes [nTPM]":"3.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.4","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"6.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"7.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"2.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.2","Single Cell Type RNA - dendritic cells [nTPM]":"4.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.9","Single Cell Type RNA - Early spermatids [nTPM]":"8.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.5","Single Cell Type RNA - Endothelial cells [nTPM]":"4.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"14.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.3","Single Cell Type RNA - Fibroblasts [nTPM]":"5.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.4","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"24.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.9","Single Cell Type RNA - Hepatocytes [nTPM]":"1.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.5","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"2.8","Single Cell Type RNA - Langerhans cells [nTPM]":"4.6","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"3.7","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.3","Single Cell Type RNA - Muller glia cells [nTPM]":"3.7","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.6","Single Cell Type RNA - Paneth cells [nTPM]":"3.9","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"9.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.8","Single Cell Type RNA - Spermatocytes [nTPM]":"71.8","Single Cell Type RNA - Spermatogonia [nTPM]":"37.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.0","Single Cell Type RNA - T-cells [nTPM]":"6.0","Single Cell Type RNA - Theca cells [nTPM]":"3.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.3","Single Cell Type RNA - Urothelial cells [nTPM]":"2.2"},{"Gene":"MCM9","Gene synonym":["C6orf61","dJ329L24.3","FLJ20170","MCMDC1","MGC35304"],"Ensembl":"ENSG00000111877","Gene description":"Minichromosome maintenance 9 homologous recombination repair factor","Uniprot":["Q9NXL9"],"Chromosome":"6","Position":"118813442-118935162","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["DNA-binding","Helicase","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"32.0","Microglial cells":"40.3","Oligodendrocyte precursor cells":"35.7","Oligodendrocytes":"39.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031137"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA031137":"AB_10602027"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.79e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.7","Tissue RNA - adrenal gland [nTPM]":"4.4","Tissue RNA - amygdala [nTPM]":"2.5","Tissue RNA - appendix [nTPM]":"5.7","Tissue RNA - basal ganglia [nTPM]":"3.3","Tissue RNA - bone marrow [nTPM]":"12.7","Tissue RNA - breast [nTPM]":"7.0","Tissue RNA - cerebellum [nTPM]":"2.4","Tissue RNA - cerebral cortex [nTPM]":"2.9","Tissue RNA - cervix [nTPM]":"6.8","Tissue RNA - choroid plexus [nTPM]":"3.5","Tissue RNA - colon [nTPM]":"5.1","Tissue RNA - duodenum [nTPM]":"4.9","Tissue RNA - endometrium 1 [nTPM]":"5.3","Tissue RNA - epididymis [nTPM]":"10.2","Tissue RNA - esophagus [nTPM]":"6.5","Tissue RNA - fallopian tube [nTPM]":"5.8","Tissue RNA - gallbladder [nTPM]":"3.7","Tissue RNA - heart muscle [nTPM]":"3.4","Tissue RNA - hippocampal formation [nTPM]":"2.2","Tissue RNA - hypothalamus [nTPM]":"2.5","Tissue RNA - kidney [nTPM]":"6.6","Tissue RNA - liver [nTPM]":"5.0","Tissue RNA - lung [nTPM]":"5.2","Tissue RNA - lymph node [nTPM]":"7.5","Tissue RNA - medulla oblongata [nTPM]":"3.2","Tissue RNA - midbrain [nTPM]":"3.2","Tissue RNA - ovary [nTPM]":"5.1","Tissue RNA - pancreas [nTPM]":"6.9","Tissue RNA - parathyroid gland [nTPM]":"5.3","Tissue RNA - pituitary gland [nTPM]":"4.6","Tissue RNA - placenta [nTPM]":"7.0","Tissue RNA - pons [nTPM]":"3.1","Tissue RNA - prostate [nTPM]":"6.8","Tissue RNA - rectum [nTPM]":"5.7","Tissue RNA - retina [nTPM]":"4.1","Tissue RNA - salivary gland [nTPM]":"7.5","Tissue RNA - seminal vesicle [nTPM]":"4.7","Tissue RNA - skeletal muscle [nTPM]":"2.6","Tissue RNA - skin 1 [nTPM]":"6.5","Tissue RNA - small intestine [nTPM]":"5.8","Tissue RNA - smooth muscle [nTPM]":"4.2","Tissue RNA - spinal cord [nTPM]":"2.8","Tissue RNA - spleen [nTPM]":"6.3","Tissue RNA - stomach 1 [nTPM]":"4.9","Tissue RNA - testis [nTPM]":"5.7","Tissue RNA - thalamus [nTPM]":"3.0","Tissue RNA - thymus [nTPM]":"8.0","Tissue RNA - thyroid gland [nTPM]":"8.0","Tissue RNA - tongue [nTPM]":"2.1","Tissue RNA - tonsil [nTPM]":"7.1","Tissue RNA - urinary bladder [nTPM]":"5.8","Tissue RNA - vagina [nTPM]":"6.9","Tissue RNA - white matter [nTPM]":"3.7","Cell RNA - A-431 [nTPM]":"4.2","Cell RNA - A549 [nTPM]":"6.5","Cell RNA - AF22 [nTPM]":"10.3","Cell RNA - AN3-CA [nTPM]":"11.8","Cell RNA - ASC diff [nTPM]":"4.2","Cell RNA - ASC TERT1 [nTPM]":"4.8","Cell RNA - BEWO [nTPM]":"7.3","Cell RNA - BJ [nTPM]":"3.9","Cell RNA - BJ hTERT+ [nTPM]":"7.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.8","Cell RNA - CACO-2 [nTPM]":"5.2","Cell RNA - CAPAN-2 [nTPM]":"6.7","Cell RNA - Daudi [nTPM]":"12.1","Cell RNA - EFO-21 [nTPM]":"4.5","Cell RNA - fHDF\/TERT166 [nTPM]":"6.2","Cell RNA - GAMG [nTPM]":"3.9","Cell RNA - HaCaT [nTPM]":"12.5","Cell RNA - HAP1 [nTPM]":"7.1","Cell RNA - HBEC3-KT [nTPM]":"4.7","Cell RNA - HBF TERT88 [nTPM]":"7.2","Cell RNA - HDLM-2 [nTPM]":"7.5","Cell RNA - HEK 293 [nTPM]":"10.1","Cell RNA - HEL [nTPM]":"11.4","Cell RNA - HeLa [nTPM]":"9.5","Cell RNA - Hep G2 [nTPM]":"5.5","Cell RNA - HHSteC [nTPM]":"3.0","Cell RNA - HL-60 [nTPM]":"11.7","Cell RNA - HMC-1 [nTPM]":"7.3","Cell RNA - HSkMC [nTPM]":"5.2","Cell RNA - hTCEpi [nTPM]":"5.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.0","Cell RNA - hTERT-HME1 [nTPM]":"7.3","Cell RNA - hTERT-RPE1 [nTPM]":"3.7","Cell RNA - HUVEC TERT2 [nTPM]":"5.5","Cell RNA - JURKAT [nTPM]":"8.0","Cell RNA - K-562 [nTPM]":"12.9","Cell RNA - Karpas-707 [nTPM]":"6.3","Cell RNA - LHCN-M2 [nTPM]":"4.2","Cell RNA - MCF7 [nTPM]":"9.4","Cell RNA - MOLT-4 [nTPM]":"10.0","Cell RNA - NB-4 [nTPM]":"9.4","Cell RNA - NTERA-2 [nTPM]":"4.7","Cell RNA - OE19 [nTPM]":"7.3","Cell RNA - PC-3 [nTPM]":"3.1","Cell RNA - REH [nTPM]":"8.3","Cell RNA - RH-30 [nTPM]":"7.0","Cell RNA - RPMI-8226 [nTPM]":"4.2","Cell RNA - RPTEC TERT1 [nTPM]":"5.4","Cell RNA - RT4 [nTPM]":"7.9","Cell RNA - SCLC-21H [nTPM]":"8.5","Cell RNA - SH-SY5Y [nTPM]":"6.0","Cell RNA - SiHa [nTPM]":"6.9","Cell RNA - SK-BR-3 [nTPM]":"5.7","Cell RNA - SK-MEL-30 [nTPM]":"3.7","Cell RNA - SuSa [nTPM]":"2.9","Cell RNA - T-47d [nTPM]":"7.3","Cell RNA - THP-1 [nTPM]":"15.8","Cell RNA - TIME [nTPM]":"6.0","Cell RNA - U-138 MG [nTPM]":"4.3","Cell RNA - U-2 OS [nTPM]":"3.7","Cell RNA - U-2197 [nTPM]":"2.9","Cell RNA - U-251 MG [nTPM]":"5.7","Cell RNA - U-266\/70 [nTPM]":"7.8","Cell RNA - U-266\/84 [nTPM]":"7.2","Cell RNA - U-698 [nTPM]":"13.9","Cell RNA - U-87 MG [nTPM]":"5.5","Cell RNA - U-937 [nTPM]":"8.7","Cell RNA - WM-115 [nTPM]":"5.6","Blood RNA - basophil [nTPM]":"4.3","Blood RNA - classical monocyte [nTPM]":"2.6","Blood RNA - eosinophil [nTPM]":"4.4","Blood RNA - gdT-cell [nTPM]":"2.2","Blood RNA - intermediate monocyte [nTPM]":"2.7","Blood RNA - MAIT T-cell [nTPM]":"1.8","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.4","Blood RNA - memory CD8 T-cell [nTPM]":"2.3","Blood RNA - myeloid DC [nTPM]":"2.9","Blood RNA - naive B-cell [nTPM]":"1.4","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.6","Blood RNA - neutrophil [nTPM]":"2.9","Blood RNA - NK-cell [nTPM]":"4.8","Blood RNA - non-classical monocyte [nTPM]":"1.7","Blood RNA - plasmacytoid DC [nTPM]":"2.1","Blood RNA - T-reg [nTPM]":"3.5","Blood RNA - total PBMC [nTPM]":"2.1","Brain RNA - amygdala [nTPM]":"2.5","Brain RNA - basal ganglia [nTPM]":"3.3","Brain RNA - cerebellum [nTPM]":"2.4","Brain RNA - cerebral cortex [nTPM]":"2.9","Brain RNA - hippocampal formation [nTPM]":"2.2","Brain RNA - hypothalamus [nTPM]":"2.5","Brain RNA - medulla oblongata [nTPM]":"3.2","Brain RNA - midbrain [nTPM]":"3.2","Brain RNA - pons [nTPM]":"3.1","Brain RNA - spinal cord [nTPM]":"2.8","Brain RNA - thalamus [nTPM]":"3.0","Brain RNA - white matter [nTPM]":"3.7","Single Cell Type RNA - Adipocytes [nTPM]":"6.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.7","Single Cell Type RNA - Astrocytes [nTPM]":"32.0","Single Cell Type RNA - B-cells [nTPM]":"10.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"3.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"4.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.8","Single Cell Type RNA - dendritic cells [nTPM]":"7.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.0","Single Cell Type RNA - Endothelial cells [nTPM]":"6.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"4.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.4","Single Cell Type RNA - Fibroblasts [nTPM]":"5.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.9","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"8.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.9","Single Cell Type RNA - Hepatocytes [nTPM]":"3.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.5","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"5.5","Single Cell Type RNA - Langerhans cells [nTPM]":"2.8","Single Cell Type RNA - Late spermatids [nTPM]":"2.6","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"7.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"40.3","Single Cell Type RNA - monocytes [nTPM]":"6.3","Single Cell Type RNA - Muller glia cells [nTPM]":"1.6","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"35.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"39.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.7","Single Cell Type RNA - Paneth cells [nTPM]":"5.6","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"10.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.8","Single Cell Type RNA - Spermatocytes [nTPM]":"6.3","Single Cell Type RNA - Spermatogonia [nTPM]":"4.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.3","Single Cell Type RNA - T-cells [nTPM]":"9.8","Single Cell Type RNA - Theca cells [nTPM]":"4.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.1","Single Cell Type RNA - Urothelial cells [nTPM]":"4.3"},{"Gene":"MCOLN1","Gene synonym":["ML4","MLIV","MST080","MSTP080","TRPM-L1","TRPML1"],"Ensembl":"ENSG00000090674","Gene description":"Mucolipin 1","Uniprot":["Q9GZU1"],"Chromosome":"19","Position":"7522624-7534009","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Adaptive immunity","Calcium transport","Immunity","Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":["Disease variant","Mucolipidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"109.4","Kupffer cells":"117.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"117.5","classical monocyte":"45.2","eosinophil":"105.7","intermediate monocyte":"95.5","neutrophil":"41.1","non-classical monocyte":"105.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"117.5","monocytes":"105.1"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031763","CAB032637","HPA069495"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB032637":"AB_2142964","HPA031763":"AB_10600822","HPA069495":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.60e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.67e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Tissue RNA - adipose tissue [nTPM]":"21.2","Tissue RNA - adrenal gland [nTPM]":"37.4","Tissue RNA - amygdala [nTPM]":"6.4","Tissue RNA - appendix [nTPM]":"9.2","Tissue RNA - basal ganglia [nTPM]":"6.5","Tissue RNA - bone marrow [nTPM]":"10.4","Tissue RNA - breast [nTPM]":"15.3","Tissue RNA - cerebellum [nTPM]":"7.0","Tissue RNA - cerebral cortex [nTPM]":"8.4","Tissue RNA - cervix [nTPM]":"11.7","Tissue RNA - choroid plexus [nTPM]":"8.3","Tissue RNA - colon [nTPM]":"13.6","Tissue RNA - duodenum [nTPM]":"8.3","Tissue RNA - endometrium 1 [nTPM]":"11.6","Tissue RNA - epididymis [nTPM]":"2.7","Tissue RNA - esophagus [nTPM]":"11.0","Tissue RNA - fallopian tube [nTPM]":"12.2","Tissue RNA - gallbladder [nTPM]":"10.1","Tissue RNA - heart muscle [nTPM]":"15.7","Tissue RNA - hippocampal formation [nTPM]":"7.0","Tissue RNA - hypothalamus [nTPM]":"7.4","Tissue RNA - kidney [nTPM]":"11.7","Tissue RNA - liver [nTPM]":"14.7","Tissue RNA - lung [nTPM]":"20.3","Tissue RNA - lymph node [nTPM]":"13.2","Tissue RNA - medulla oblongata [nTPM]":"8.2","Tissue RNA - midbrain [nTPM]":"7.4","Tissue RNA - ovary [nTPM]":"10.0","Tissue RNA - pancreas [nTPM]":"9.9","Tissue RNA - parathyroid gland [nTPM]":"10.2","Tissue RNA - pituitary gland [nTPM]":"21.7","Tissue RNA - placenta [nTPM]":"15.9","Tissue RNA - pons [nTPM]":"9.0","Tissue RNA - prostate [nTPM]":"8.7","Tissue RNA - rectum [nTPM]":"5.6","Tissue RNA - retina [nTPM]":"5.0","Tissue RNA - salivary gland [nTPM]":"12.3","Tissue RNA - seminal vesicle [nTPM]":"6.1","Tissue RNA - skeletal muscle [nTPM]":"22.2","Tissue RNA - skin 1 [nTPM]":"20.8","Tissue RNA - small intestine [nTPM]":"12.1","Tissue RNA - smooth muscle [nTPM]":"8.1","Tissue RNA - spinal cord [nTPM]":"7.1","Tissue RNA - spleen [nTPM]":"48.2","Tissue RNA - stomach 1 [nTPM]":"12.8","Tissue RNA - testis [nTPM]":"5.6","Tissue RNA - thalamus [nTPM]":"8.2","Tissue RNA - thymus [nTPM]":"6.2","Tissue RNA - thyroid gland [nTPM]":"8.5","Tissue RNA - tongue [nTPM]":"11.7","Tissue RNA - tonsil [nTPM]":"4.1","Tissue RNA - urinary bladder [nTPM]":"15.8","Tissue RNA - vagina [nTPM]":"10.9","Tissue RNA - white matter [nTPM]":"9.9","Cell RNA - A-431 [nTPM]":"11.6","Cell RNA - A549 [nTPM]":"11.7","Cell RNA - AF22 [nTPM]":"5.6","Cell RNA - AN3-CA [nTPM]":"19.1","Cell RNA - ASC diff [nTPM]":"32.0","Cell RNA - ASC TERT1 [nTPM]":"10.3","Cell RNA - BEWO [nTPM]":"16.1","Cell RNA - BJ [nTPM]":"21.2","Cell RNA - BJ hTERT+ [nTPM]":"16.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"25.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.6","Cell RNA - CACO-2 [nTPM]":"9.0","Cell RNA - CAPAN-2 [nTPM]":"10.0","Cell RNA - Daudi [nTPM]":"6.5","Cell RNA - EFO-21 [nTPM]":"25.5","Cell RNA - fHDF\/TERT166 [nTPM]":"14.5","Cell RNA - GAMG [nTPM]":"22.2","Cell RNA - HaCaT [nTPM]":"5.3","Cell RNA - HAP1 [nTPM]":"9.5","Cell RNA - HBEC3-KT [nTPM]":"7.3","Cell RNA - HBF TERT88 [nTPM]":"7.4","Cell RNA - HDLM-2 [nTPM]":"12.7","Cell RNA - HEK 293 [nTPM]":"21.1","Cell RNA - HEL [nTPM]":"5.8","Cell RNA - HeLa [nTPM]":"11.0","Cell RNA - Hep G2 [nTPM]":"7.3","Cell RNA - HHSteC [nTPM]":"28.0","Cell RNA - HL-60 [nTPM]":"6.6","Cell RNA - HMC-1 [nTPM]":"24.5","Cell RNA - HSkMC [nTPM]":"14.5","Cell RNA - hTCEpi [nTPM]":"16.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"24.1","Cell RNA - hTERT-HME1 [nTPM]":"4.2","Cell RNA - hTERT-RPE1 [nTPM]":"7.9","Cell RNA - HUVEC TERT2 [nTPM]":"10.7","Cell RNA - JURKAT [nTPM]":"14.2","Cell RNA - K-562 [nTPM]":"10.9","Cell RNA - Karpas-707 [nTPM]":"27.9","Cell RNA - LHCN-M2 [nTPM]":"14.7","Cell RNA - MCF7 [nTPM]":"3.9","Cell RNA - MOLT-4 [nTPM]":"9.1","Cell RNA - NB-4 [nTPM]":"6.6","Cell RNA - NTERA-2 [nTPM]":"12.6","Cell RNA - OE19 [nTPM]":"6.1","Cell RNA - PC-3 [nTPM]":"24.8","Cell RNA - REH [nTPM]":"12.6","Cell RNA - RH-30 [nTPM]":"9.4","Cell RNA - RPMI-8226 [nTPM]":"13.8","Cell RNA - RPTEC TERT1 [nTPM]":"9.6","Cell RNA - RT4 [nTPM]":"9.9","Cell RNA - SCLC-21H [nTPM]":"14.4","Cell RNA - SH-SY5Y [nTPM]":"17.8","Cell RNA - SiHa [nTPM]":"9.1","Cell RNA - SK-BR-3 [nTPM]":"15.8","Cell RNA - SK-MEL-30 [nTPM]":"26.8","Cell RNA - SuSa [nTPM]":"6.1","Cell RNA - T-47d [nTPM]":"9.6","Cell RNA - THP-1 [nTPM]":"11.4","Cell RNA - TIME [nTPM]":"13.5","Cell RNA - U-138 MG [nTPM]":"12.0","Cell RNA - U-2 OS [nTPM]":"6.9","Cell RNA - U-2197 [nTPM]":"48.8","Cell RNA - U-251 MG [nTPM]":"16.0","Cell RNA - U-266\/70 [nTPM]":"21.5","Cell RNA - U-266\/84 [nTPM]":"35.5","Cell RNA - U-698 [nTPM]":"4.7","Cell RNA - U-87 MG [nTPM]":"19.2","Cell RNA - U-937 [nTPM]":"9.2","Cell RNA - WM-115 [nTPM]":"18.4","Blood RNA - basophil [nTPM]":"117.5","Blood RNA - classical monocyte [nTPM]":"45.2","Blood RNA - eosinophil [nTPM]":"105.7","Blood RNA - gdT-cell [nTPM]":"7.7","Blood RNA - intermediate monocyte [nTPM]":"95.5","Blood RNA - MAIT T-cell [nTPM]":"6.3","Blood RNA - memory B-cell [nTPM]":"4.2","Blood RNA - memory CD4 T-cell [nTPM]":"6.5","Blood RNA - memory CD8 T-cell [nTPM]":"6.3","Blood RNA - myeloid DC [nTPM]":"19.2","Blood RNA - naive B-cell [nTPM]":"4.1","Blood RNA - naive CD4 T-cell [nTPM]":"6.0","Blood RNA - naive CD8 T-cell [nTPM]":"6.5","Blood RNA - neutrophil [nTPM]":"41.1","Blood RNA - NK-cell [nTPM]":"10.3","Blood RNA - non-classical monocyte [nTPM]":"105.1","Blood RNA - plasmacytoid DC [nTPM]":"21.1","Blood RNA - T-reg [nTPM]":"10.0","Blood RNA - total PBMC [nTPM]":"17.1","Brain RNA - amygdala [nTPM]":"6.4","Brain RNA - basal ganglia [nTPM]":"6.5","Brain RNA - cerebellum [nTPM]":"7.0","Brain RNA - cerebral cortex [nTPM]":"8.4","Brain RNA - hippocampal formation [nTPM]":"7.0","Brain RNA - hypothalamus [nTPM]":"7.4","Brain RNA - medulla oblongata [nTPM]":"8.2","Brain RNA - midbrain [nTPM]":"7.4","Brain RNA - pons [nTPM]":"9.0","Brain RNA - spinal cord [nTPM]":"7.1","Brain RNA - thalamus [nTPM]":"8.2","Brain RNA - white matter [nTPM]":"9.9","Single Cell Type RNA - Adipocytes [nTPM]":"15.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.6","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"8.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"27.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"8.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.6","Single Cell Type RNA - dendritic cells [nTPM]":"12.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"32.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"23.7","Single Cell Type RNA - Early spermatids [nTPM]":"4.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.8","Single Cell Type RNA - Endothelial cells [nTPM]":"14.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.8","Single Cell Type RNA - Erythroid cells [nTPM]":"21.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.0","Single Cell Type RNA - Fibroblasts [nTPM]":"16.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"22.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"13.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"109.4","Single Cell Type RNA - Horizontal cells [nTPM]":"58.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.0","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"117.1","Single Cell Type RNA - Langerhans cells [nTPM]":"32.2","Single Cell Type RNA - Late spermatids [nTPM]":"17.0","Single Cell Type RNA - Leydig cells [nTPM]":"16.4","Single Cell Type RNA - Macrophages [nTPM]":"70.6","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"18.0","Single Cell Type RNA - Muller glia cells [nTPM]":"23.0","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"23.4","Single Cell Type RNA - Paneth cells [nTPM]":"19.3","Single Cell Type RNA - Peritubular cells [nTPM]":"15.8","Single Cell Type RNA - Plasma cells [nTPM]":"8.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"21.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"44.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.8","Single Cell Type RNA - Spermatocytes [nTPM]":"10.3","Single Cell Type RNA - Spermatogonia [nTPM]":"14.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"29.6","Single Cell Type RNA - T-cells [nTPM]":"8.7","Single Cell Type RNA - Theca cells [nTPM]":"17.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.4","Single Cell Type RNA - Urothelial cells [nTPM]":"4.8"},{"Gene":"MCTP2","Gene synonym":["FLJ11175","FLJ33303"],"Ensembl":"ENSG00000140563","Gene description":"Multiple C2 and transmembrane domain containing 2","Uniprot":["Q6DN12"],"Chromosome":"15","Position":"94231538-94483952","Protein class":["Disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"72.8","NK-cells":"97.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"6.8"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"32.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"20.8","HMC-1":"16.4","U-698":"22.4","U-87 MG":"24.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051176","HPA070541"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA051176":"AB_2681373","HPA070541":"AB_2686277"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.18e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.1","Tissue RNA - adrenal gland [nTPM]":"3.8","Tissue RNA - amygdala [nTPM]":"1.0","Tissue RNA - appendix [nTPM]":"6.6","Tissue RNA - basal ganglia [nTPM]":"1.8","Tissue RNA - bone marrow [nTPM]":"18.0","Tissue RNA - breast [nTPM]":"2.9","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"6.8","Tissue RNA - cervix [nTPM]":"5.4","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"10.6","Tissue RNA - duodenum [nTPM]":"6.9","Tissue RNA - endometrium 1 [nTPM]":"1.8","Tissue RNA - epididymis [nTPM]":"8.6","Tissue RNA - esophagus [nTPM]":"3.9","Tissue RNA - fallopian tube [nTPM]":"4.1","Tissue RNA - gallbladder [nTPM]":"4.5","Tissue RNA - heart muscle [nTPM]":"0.6","Tissue RNA - hippocampal formation [nTPM]":"1.1","Tissue RNA - hypothalamus [nTPM]":"2.8","Tissue RNA - kidney [nTPM]":"2.3","Tissue RNA - liver [nTPM]":"1.5","Tissue RNA - lung [nTPM]":"8.7","Tissue RNA - lymph node [nTPM]":"6.1","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"1.6","Tissue RNA - pancreas [nTPM]":"5.7","Tissue RNA - parathyroid gland [nTPM]":"3.5","Tissue RNA - pituitary gland [nTPM]":"7.3","Tissue RNA - placenta [nTPM]":"19.3","Tissue RNA - pons [nTPM]":"1.0","Tissue RNA - prostate [nTPM]":"5.4","Tissue RNA - rectum [nTPM]":"12.2","Tissue RNA - retina [nTPM]":"2.6","Tissue RNA - salivary gland [nTPM]":"5.9","Tissue RNA - seminal vesicle [nTPM]":"4.1","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"3.6","Tissue RNA - small intestine [nTPM]":"6.4","Tissue RNA - smooth muscle [nTPM]":"1.6","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"21.1","Tissue RNA - stomach 1 [nTPM]":"4.7","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"1.3","Tissue RNA - thymus [nTPM]":"3.0","Tissue RNA - thyroid gland [nTPM]":"5.5","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"6.2","Tissue RNA - urinary bladder [nTPM]":"6.6","Tissue RNA - vagina [nTPM]":"3.7","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"3.6","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"2.5","Cell RNA - BJ [nTPM]":"1.9","Cell RNA - BJ hTERT+ [nTPM]":"1.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"2.4","Cell RNA - CAPAN-2 [nTPM]":"4.4","Cell RNA - Daudi [nTPM]":"10.3","Cell RNA - EFO-21 [nTPM]":"0.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"8.0","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"6.6","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"2.1","Cell RNA - HEK 293 [nTPM]":"0.8","Cell RNA - HEL [nTPM]":"20.8","Cell RNA - HeLa [nTPM]":"2.9","Cell RNA - Hep G2 [nTPM]":"1.2","Cell RNA - HHSteC [nTPM]":"1.4","Cell RNA - HL-60 [nTPM]":"4.4","Cell RNA - HMC-1 [nTPM]":"16.4","Cell RNA - HSkMC [nTPM]":"1.1","Cell RNA - hTCEpi [nTPM]":"7.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"8.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"3.6","Cell RNA - K-562 [nTPM]":"0.8","Cell RNA - Karpas-707 [nTPM]":"5.9","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"2.0","Cell RNA - NB-4 [nTPM]":"11.4","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"3.6","Cell RNA - PC-3 [nTPM]":"3.7","Cell RNA - REH [nTPM]":"4.7","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"4.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.5","Cell RNA - RT4 [nTPM]":"10.7","Cell RNA - SCLC-21H [nTPM]":"1.9","Cell RNA - SH-SY5Y [nTPM]":"0.4","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"3.4","Cell RNA - SK-MEL-30 [nTPM]":"1.3","Cell RNA - SuSa [nTPM]":"0.8","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"1.7","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"12.0","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"22.4","Cell RNA - U-87 MG [nTPM]":"24.1","Cell RNA - U-937 [nTPM]":"11.1","Cell RNA - WM-115 [nTPM]":"1.2","Blood RNA - basophil [nTPM]":"6.6","Blood RNA - classical monocyte [nTPM]":"0.8","Blood RNA - eosinophil [nTPM]":"12.1","Blood RNA - gdT-cell [nTPM]":"6.1","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"3.0","Blood RNA - memory B-cell [nTPM]":"3.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.7","Blood RNA - memory CD8 T-cell [nTPM]":"2.8","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"3.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"2.7","Blood RNA - neutrophil [nTPM]":"32.1","Blood RNA - NK-cell [nTPM]":"10.9","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"1.9","Brain RNA - amygdala [nTPM]":"1.0","Brain RNA - basal ganglia [nTPM]":"1.8","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"6.8","Brain RNA - hippocampal formation [nTPM]":"1.1","Brain RNA - hypothalamus [nTPM]":"2.8","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"1.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"1.3","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"1.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.6","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"38.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.8","Single Cell Type RNA - Bipolar cells [nTPM]":"15.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"13.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"17.0","Single Cell Type RNA - dendritic cells [nTPM]":"72.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"39.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.4","Single Cell Type RNA - Early spermatids [nTPM]":"4.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.4","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.6","Single Cell Type RNA - Erythroid cells [nTPM]":"35.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.3","Single Cell Type RNA - Fibroblasts [nTPM]":"7.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.6","Single Cell Type RNA - granulocytes [nTPM]":"36.2","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"1.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"43.8","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"8.7","Single Cell Type RNA - Langerhans cells [nTPM]":"2.1","Single Cell Type RNA - Late spermatids [nTPM]":"4.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"11.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"25.3","Single Cell Type RNA - monocytes [nTPM]":"4.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"97.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.2","Single Cell Type RNA - Paneth cells [nTPM]":"24.6","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"45.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.6","Single Cell Type RNA - Spermatocytes [nTPM]":"3.4","Single Cell Type RNA - Spermatogonia [nTPM]":"2.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"24.5","Single Cell Type RNA - T-cells [nTPM]":"26.6","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"21.5","Single Cell Type RNA - Urothelial cells [nTPM]":"19.6"},{"Gene":"MDH1","Gene synonym":[],"Ensembl":"ENSG00000014641","Gene description":"Malate dehydrogenase 1","Uniprot":["P40925"],"Chromosome":"2","Position":"63588609-63607197","Protein class":["Cancer-related genes","Citric acid cycle related proteins","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Tricarboxylic acid cycle"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Cancer-related genes","Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"1349.1","tongue":"1843.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"1926.9","Proximal tubular cells":"1428.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027296","CAB047333","HPA054276"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"49000000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Centrosome","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB047333":null,"HPA027296":"AB_10611118","HPA054276":"AB_2682434"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.13e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.95e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Tissue RNA - adipose tissue [nTPM]":"274.6","Tissue RNA - adrenal gland [nTPM]":"213.6","Tissue RNA - amygdala [nTPM]":"235.9","Tissue RNA - appendix [nTPM]":"86.7","Tissue RNA - basal ganglia [nTPM]":"249.7","Tissue RNA - bone marrow [nTPM]":"79.1","Tissue RNA - breast [nTPM]":"137.9","Tissue RNA - cerebellum [nTPM]":"245.9","Tissue RNA - cerebral cortex [nTPM]":"353.6","Tissue RNA - cervix [nTPM]":"89.6","Tissue RNA - choroid plexus [nTPM]":"230.2","Tissue RNA - colon [nTPM]":"167.7","Tissue RNA - duodenum [nTPM]":"154.7","Tissue RNA - endometrium 1 [nTPM]":"82.0","Tissue RNA - epididymis [nTPM]":"161.3","Tissue RNA - esophagus [nTPM]":"125.3","Tissue RNA - fallopian tube [nTPM]":"114.5","Tissue RNA - gallbladder [nTPM]":"87.2","Tissue RNA - heart muscle [nTPM]":"1349.1","Tissue RNA - hippocampal formation [nTPM]":"253.2","Tissue RNA - hypothalamus [nTPM]":"261.5","Tissue RNA - kidney [nTPM]":"371.6","Tissue RNA - liver [nTPM]":"266.3","Tissue RNA - lung [nTPM]":"89.8","Tissue RNA - lymph node [nTPM]":"131.9","Tissue RNA - medulla oblongata [nTPM]":"248.5","Tissue RNA - midbrain [nTPM]":"218.3","Tissue RNA - ovary [nTPM]":"80.4","Tissue RNA - pancreas [nTPM]":"69.9","Tissue RNA - parathyroid gland [nTPM]":"411.8","Tissue RNA - pituitary gland [nTPM]":"107.2","Tissue RNA - placenta [nTPM]":"92.5","Tissue RNA - pons [nTPM]":"253.3","Tissue RNA - prostate [nTPM]":"125.5","Tissue RNA - rectum [nTPM]":"190.9","Tissue RNA - retina [nTPM]":"240.7","Tissue RNA - salivary gland [nTPM]":"122.0","Tissue RNA - seminal vesicle [nTPM]":"142.0","Tissue RNA - skeletal muscle [nTPM]":"792.5","Tissue RNA - skin 1 [nTPM]":"87.7","Tissue RNA - small intestine [nTPM]":"133.1","Tissue RNA - smooth muscle [nTPM]":"171.5","Tissue RNA - spinal cord [nTPM]":"215.7","Tissue RNA - spleen [nTPM]":"71.6","Tissue RNA - stomach 1 [nTPM]":"192.6","Tissue RNA - testis [nTPM]":"70.5","Tissue RNA - thalamus [nTPM]":"259.1","Tissue RNA - thymus [nTPM]":"170.4","Tissue RNA - thyroid gland [nTPM]":"125.5","Tissue RNA - tongue [nTPM]":"1843.8","Tissue RNA - tonsil [nTPM]":"165.4","Tissue RNA - urinary bladder [nTPM]":"131.5","Tissue RNA - vagina [nTPM]":"62.8","Tissue RNA - white matter [nTPM]":"237.7","Cell RNA - A-431 [nTPM]":"268.2","Cell RNA - A549 [nTPM]":"219.5","Cell RNA - AF22 [nTPM]":"257.8","Cell RNA - AN3-CA [nTPM]":"173.2","Cell RNA - ASC diff [nTPM]":"369.6","Cell RNA - ASC TERT1 [nTPM]":"280.9","Cell RNA - BEWO [nTPM]":"282.3","Cell RNA - BJ [nTPM]":"215.1","Cell RNA - BJ hTERT+ [nTPM]":"295.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"300.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"304.1","Cell RNA - CACO-2 [nTPM]":"252.5","Cell RNA - CAPAN-2 [nTPM]":"215.4","Cell RNA - Daudi [nTPM]":"355.2","Cell RNA - EFO-21 [nTPM]":"112.8","Cell RNA - fHDF\/TERT166 [nTPM]":"264.1","Cell RNA - GAMG [nTPM]":"358.8","Cell RNA - HaCaT [nTPM]":"214.3","Cell RNA - HAP1 [nTPM]":"303.0","Cell RNA - HBEC3-KT [nTPM]":"355.0","Cell RNA - HBF TERT88 [nTPM]":"425.5","Cell RNA - HDLM-2 [nTPM]":"207.6","Cell RNA - HEK 293 [nTPM]":"253.1","Cell RNA - HEL [nTPM]":"337.0","Cell RNA - HeLa [nTPM]":"173.2","Cell RNA - Hep G2 [nTPM]":"376.8","Cell RNA - HHSteC [nTPM]":"202.1","Cell RNA - HL-60 [nTPM]":"384.1","Cell RNA - HMC-1 [nTPM]":"223.9","Cell RNA - HSkMC [nTPM]":"277.7","Cell RNA - hTCEpi [nTPM]":"241.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"271.5","Cell RNA - hTERT-HME1 [nTPM]":"152.7","Cell RNA - hTERT-RPE1 [nTPM]":"236.2","Cell RNA - HUVEC TERT2 [nTPM]":"235.3","Cell RNA - JURKAT [nTPM]":"308.1","Cell RNA - K-562 [nTPM]":"183.7","Cell RNA - Karpas-707 [nTPM]":"217.3","Cell RNA - LHCN-M2 [nTPM]":"395.1","Cell RNA - MCF7 [nTPM]":"157.8","Cell RNA - MOLT-4 [nTPM]":"300.6","Cell RNA - NB-4 [nTPM]":"317.5","Cell RNA - NTERA-2 [nTPM]":"158.0","Cell RNA - OE19 [nTPM]":"376.3","Cell RNA - PC-3 [nTPM]":"266.5","Cell RNA - REH [nTPM]":"235.2","Cell RNA - RH-30 [nTPM]":"349.7","Cell RNA - RPMI-8226 [nTPM]":"310.5","Cell RNA - RPTEC TERT1 [nTPM]":"460.9","Cell RNA - RT4 [nTPM]":"251.0","Cell RNA - SCLC-21H [nTPM]":"249.9","Cell RNA - SH-SY5Y [nTPM]":"153.6","Cell RNA - SiHa [nTPM]":"182.5","Cell RNA - SK-BR-3 [nTPM]":"257.7","Cell RNA - SK-MEL-30 [nTPM]":"384.1","Cell RNA - SuSa [nTPM]":"205.6","Cell RNA - T-47d [nTPM]":"191.9","Cell RNA - THP-1 [nTPM]":"341.9","Cell RNA - TIME [nTPM]":"149.6","Cell RNA - U-138 MG [nTPM]":"220.3","Cell RNA - U-2 OS [nTPM]":"211.9","Cell RNA - U-2197 [nTPM]":"187.1","Cell RNA - U-251 MG [nTPM]":"252.9","Cell RNA - U-266\/70 [nTPM]":"264.6","Cell RNA - U-266\/84 [nTPM]":"264.8","Cell RNA - U-698 [nTPM]":"407.6","Cell RNA - U-87 MG [nTPM]":"266.2","Cell RNA - U-937 [nTPM]":"312.2","Cell RNA - WM-115 [nTPM]":"184.1","Blood RNA - basophil [nTPM]":"271.3","Blood RNA - classical monocyte [nTPM]":"186.3","Blood RNA - eosinophil [nTPM]":"200.2","Blood RNA - gdT-cell [nTPM]":"202.7","Blood RNA - intermediate monocyte [nTPM]":"267.8","Blood RNA - MAIT T-cell [nTPM]":"218.8","Blood RNA - memory B-cell [nTPM]":"258.5","Blood RNA - memory CD4 T-cell [nTPM]":"236.6","Blood RNA - memory CD8 T-cell [nTPM]":"224.6","Blood RNA - myeloid DC [nTPM]":"241.0","Blood RNA - naive B-cell [nTPM]":"258.5","Blood RNA - naive CD4 T-cell [nTPM]":"230.3","Blood RNA - naive CD8 T-cell [nTPM]":"221.6","Blood RNA - neutrophil [nTPM]":"28.1","Blood RNA - NK-cell [nTPM]":"214.6","Blood RNA - non-classical monocyte [nTPM]":"253.4","Blood RNA - plasmacytoid DC [nTPM]":"184.3","Blood RNA - T-reg [nTPM]":"320.9","Blood RNA - total PBMC [nTPM]":"321.2","Brain RNA - amygdala [nTPM]":"235.9","Brain RNA - basal ganglia [nTPM]":"249.7","Brain RNA - cerebellum [nTPM]":"245.9","Brain RNA - cerebral cortex [nTPM]":"353.6","Brain RNA - hippocampal formation [nTPM]":"253.2","Brain RNA - hypothalamus [nTPM]":"261.5","Brain RNA - medulla oblongata [nTPM]":"248.5","Brain RNA - midbrain [nTPM]":"218.3","Brain RNA - pons [nTPM]":"253.3","Brain RNA - spinal cord [nTPM]":"215.7","Brain RNA - thalamus [nTPM]":"259.1","Brain RNA - white matter [nTPM]":"237.7","Single Cell Type RNA - Adipocytes [nTPM]":"44.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"54.3","Single Cell Type RNA - Astrocytes [nTPM]":"54.9","Single Cell Type RNA - B-cells [nTPM]":"78.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"81.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"109.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"562.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"50.7","Single Cell Type RNA - Bipolar cells [nTPM]":"165.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"81.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"86.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1926.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"95.8","Single Cell Type RNA - Club cells [nTPM]":"227.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"134.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"70.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"248.7","Single Cell Type RNA - dendritic cells [nTPM]":"78.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"128.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"630.0","Single Cell Type RNA - Ductal cells [nTPM]":"186.2","Single Cell Type RNA - Early spermatids [nTPM]":"12.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"116.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"72.6","Single Cell Type RNA - Endothelial cells [nTPM]":"61.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"62.8","Single Cell Type RNA - Erythroid cells [nTPM]":"62.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"120.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"108.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"257.0","Single Cell Type RNA - Fibroblasts [nTPM]":"134.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"112.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"68.8","Single Cell Type RNA - granulocytes [nTPM]":"80.5","Single Cell Type RNA - Granulosa cells [nTPM]":"95.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"36.0","Single Cell Type RNA - Hepatocytes [nTPM]":"153.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"397.0","Single Cell Type RNA - Horizontal cells [nTPM]":"122.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"130.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"115.9","Single Cell Type RNA - Ionocytes [nTPM]":"380.5","Single Cell Type RNA - Kupffer cells [nTPM]":"85.2","Single Cell Type RNA - Langerhans cells [nTPM]":"65.8","Single Cell Type RNA - Late spermatids [nTPM]":"15.1","Single Cell Type RNA - Leydig cells [nTPM]":"100.0","Single Cell Type RNA - Macrophages [nTPM]":"98.4","Single Cell Type RNA - Melanocytes [nTPM]":"177.9","Single Cell Type RNA - Microglial cells [nTPM]":"43.1","Single Cell Type RNA - monocytes [nTPM]":"155.0","Single Cell Type RNA - Muller glia cells [nTPM]":"136.3","Single Cell Type RNA - NK-cells [nTPM]":"73.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"51.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"58.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"91.3","Single Cell Type RNA - Paneth cells [nTPM]":"99.8","Single Cell Type RNA - Peritubular cells [nTPM]":"109.1","Single Cell Type RNA - Plasma cells [nTPM]":"82.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"48.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"177.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1428.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"224.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"164.1","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"68.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"167.8","Single Cell Type RNA - Spermatocytes [nTPM]":"58.0","Single Cell Type RNA - Spermatogonia [nTPM]":"65.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"82.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"84.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"149.5","Single Cell Type RNA - T-cells [nTPM]":"84.3","Single Cell Type RNA - Theca cells [nTPM]":"137.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"167.8","Single Cell Type RNA - Urothelial cells [nTPM]":"102.6"},{"Gene":"MDM2","Gene synonym":["HDM2","MGC5370"],"Ensembl":"ENSG00000135679","Gene description":"MDM2 proto-oncogene","Uniprot":["Q00987"],"Chromosome":"12","Position":"68808177-68850686","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Host-virus interaction","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"257.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HBEC3-KT":"504.6","U-698":"517.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000086","CAB016303","CAB079977"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB000086":"AB_563872","CAB016303":"AB_627920","CAB079977":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.23e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.51e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-2"},"Tissue RNA - adipose tissue [nTPM]":"14.0","Tissue RNA - adrenal gland [nTPM]":"11.6","Tissue RNA - amygdala [nTPM]":"5.4","Tissue RNA - appendix [nTPM]":"10.4","Tissue RNA - basal ganglia [nTPM]":"10.0","Tissue RNA - bone marrow [nTPM]":"28.6","Tissue RNA - breast [nTPM]":"11.9","Tissue RNA - cerebellum [nTPM]":"7.4","Tissue RNA - cerebral cortex [nTPM]":"7.6","Tissue RNA - cervix [nTPM]":"13.9","Tissue RNA - choroid plexus [nTPM]":"28.0","Tissue RNA - colon [nTPM]":"20.7","Tissue RNA - duodenum [nTPM]":"6.4","Tissue RNA - endometrium 1 [nTPM]":"9.5","Tissue RNA - epididymis [nTPM]":"7.1","Tissue RNA - esophagus [nTPM]":"13.0","Tissue RNA - fallopian tube [nTPM]":"14.1","Tissue RNA - gallbladder [nTPM]":"12.0","Tissue RNA - heart muscle [nTPM]":"6.8","Tissue RNA - hippocampal formation [nTPM]":"3.8","Tissue RNA - hypothalamus [nTPM]":"7.4","Tissue RNA - kidney [nTPM]":"9.5","Tissue RNA - liver [nTPM]":"26.9","Tissue RNA - lung [nTPM]":"14.3","Tissue RNA - lymph node [nTPM]":"13.8","Tissue RNA - medulla oblongata [nTPM]":"9.9","Tissue RNA - midbrain [nTPM]":"8.5","Tissue RNA - ovary [nTPM]":"10.8","Tissue RNA - pancreas [nTPM]":"14.3","Tissue RNA - parathyroid gland [nTPM]":"10.9","Tissue RNA - pituitary gland [nTPM]":"5.0","Tissue RNA - placenta [nTPM]":"16.4","Tissue RNA - pons [nTPM]":"9.2","Tissue RNA - prostate [nTPM]":"11.3","Tissue RNA - rectum [nTPM]":"21.9","Tissue RNA - retina [nTPM]":"14.2","Tissue RNA - salivary gland [nTPM]":"9.6","Tissue RNA - seminal vesicle [nTPM]":"11.5","Tissue RNA - skeletal muscle [nTPM]":"18.6","Tissue RNA - skin 1 [nTPM]":"10.9","Tissue RNA - small intestine [nTPM]":"7.5","Tissue RNA - smooth muscle [nTPM]":"12.4","Tissue RNA - spinal cord [nTPM]":"6.0","Tissue RNA - spleen [nTPM]":"11.4","Tissue RNA - stomach 1 [nTPM]":"10.0","Tissue RNA - testis [nTPM]":"6.6","Tissue RNA - thalamus [nTPM]":"9.2","Tissue RNA - thymus [nTPM]":"15.6","Tissue RNA - thyroid gland [nTPM]":"15.4","Tissue RNA - tongue [nTPM]":"12.9","Tissue RNA - tonsil [nTPM]":"17.0","Tissue RNA - urinary bladder [nTPM]":"15.1","Tissue RNA - vagina [nTPM]":"10.8","Tissue RNA - white matter [nTPM]":"12.8","Cell RNA - A-431 [nTPM]":"18.7","Cell RNA - A549 [nTPM]":"42.1","Cell RNA - AF22 [nTPM]":"43.5","Cell RNA - AN3-CA [nTPM]":"22.6","Cell RNA - ASC diff [nTPM]":"55.9","Cell RNA - ASC TERT1 [nTPM]":"51.5","Cell RNA - BEWO [nTPM]":"223.4","Cell RNA - BJ [nTPM]":"49.7","Cell RNA - BJ hTERT+ [nTPM]":"50.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"26.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"41.5","Cell RNA - CACO-2 [nTPM]":"26.8","Cell RNA - CAPAN-2 [nTPM]":"8.4","Cell RNA - Daudi [nTPM]":"188.6","Cell RNA - EFO-21 [nTPM]":"13.5","Cell RNA - fHDF\/TERT166 [nTPM]":"34.7","Cell RNA - GAMG [nTPM]":"7.3","Cell RNA - HaCaT [nTPM]":"11.0","Cell RNA - HAP1 [nTPM]":"31.4","Cell RNA - HBEC3-KT [nTPM]":"504.6","Cell RNA - HBF TERT88 [nTPM]":"42.1","Cell RNA - HDLM-2 [nTPM]":"51.0","Cell RNA - HEK 293 [nTPM]":"22.0","Cell RNA - HEL [nTPM]":"35.3","Cell RNA - HeLa [nTPM]":"36.0","Cell RNA - Hep G2 [nTPM]":"115.0","Cell RNA - HHSteC [nTPM]":"55.7","Cell RNA - HL-60 [nTPM]":"32.6","Cell RNA - HMC-1 [nTPM]":"31.0","Cell RNA - HSkMC [nTPM]":"77.8","Cell RNA - hTCEpi [nTPM]":"46.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"101.5","Cell RNA - hTERT-HME1 [nTPM]":"69.4","Cell RNA - hTERT-RPE1 [nTPM]":"26.9","Cell RNA - HUVEC TERT2 [nTPM]":"73.7","Cell RNA - JURKAT [nTPM]":"32.1","Cell RNA - K-562 [nTPM]":"37.1","Cell RNA - Karpas-707 [nTPM]":"45.4","Cell RNA - LHCN-M2 [nTPM]":"50.8","Cell RNA - MCF7 [nTPM]":"28.0","Cell RNA - MOLT-4 [nTPM]":"43.1","Cell RNA - NB-4 [nTPM]":"10.7","Cell RNA - NTERA-2 [nTPM]":"36.9","Cell RNA - OE19 [nTPM]":"10.1","Cell RNA - PC-3 [nTPM]":"8.2","Cell RNA - REH [nTPM]":"149.4","Cell RNA - RH-30 [nTPM]":"31.7","Cell RNA - RPMI-8226 [nTPM]":"16.2","Cell RNA - RPTEC TERT1 [nTPM]":"16.0","Cell RNA - RT4 [nTPM]":"146.0","Cell RNA - SCLC-21H [nTPM]":"34.3","Cell RNA - SH-SY5Y [nTPM]":"20.2","Cell RNA - SiHa [nTPM]":"32.0","Cell RNA - SK-BR-3 [nTPM]":"25.0","Cell RNA - SK-MEL-30 [nTPM]":"11.3","Cell RNA - SuSa [nTPM]":"88.8","Cell RNA - T-47d [nTPM]":"58.3","Cell RNA - THP-1 [nTPM]":"21.4","Cell RNA - TIME [nTPM]":"82.3","Cell RNA - U-138 MG [nTPM]":"20.2","Cell RNA - U-2 OS [nTPM]":"38.0","Cell RNA - U-2197 [nTPM]":"16.8","Cell RNA - U-251 MG [nTPM]":"18.5","Cell RNA - U-266\/70 [nTPM]":"68.2","Cell RNA - U-266\/84 [nTPM]":"47.7","Cell RNA - U-698 [nTPM]":"517.6","Cell RNA - U-87 MG [nTPM]":"31.3","Cell RNA - U-937 [nTPM]":"12.8","Cell RNA - WM-115 [nTPM]":"81.2","Blood RNA - basophil [nTPM]":"6.1","Blood RNA - classical monocyte [nTPM]":"5.4","Blood RNA - eosinophil [nTPM]":"5.2","Blood RNA - gdT-cell [nTPM]":"4.1","Blood RNA - intermediate monocyte [nTPM]":"4.1","Blood RNA - MAIT T-cell [nTPM]":"3.7","Blood RNA - memory B-cell [nTPM]":"4.7","Blood RNA - memory CD4 T-cell [nTPM]":"3.5","Blood RNA - memory CD8 T-cell [nTPM]":"4.1","Blood RNA - myeloid DC [nTPM]":"3.0","Blood RNA - naive B-cell [nTPM]":"5.4","Blood RNA - naive CD4 T-cell [nTPM]":"3.6","Blood RNA - naive CD8 T-cell [nTPM]":"3.5","Blood RNA - neutrophil [nTPM]":"19.2","Blood RNA - NK-cell [nTPM]":"3.7","Blood RNA - non-classical monocyte [nTPM]":"7.2","Blood RNA - plasmacytoid DC [nTPM]":"3.9","Blood RNA - T-reg [nTPM]":"4.1","Blood RNA - total PBMC [nTPM]":"3.6","Brain RNA - amygdala [nTPM]":"5.4","Brain RNA - basal ganglia [nTPM]":"10.0","Brain RNA - cerebellum [nTPM]":"7.4","Brain RNA - cerebral cortex [nTPM]":"7.6","Brain RNA - hippocampal formation [nTPM]":"3.8","Brain RNA - hypothalamus [nTPM]":"7.4","Brain RNA - medulla oblongata [nTPM]":"9.9","Brain RNA - midbrain [nTPM]":"8.5","Brain RNA - pons [nTPM]":"9.2","Brain RNA - spinal cord [nTPM]":"6.0","Brain RNA - thalamus [nTPM]":"9.2","Brain RNA - white matter [nTPM]":"12.8","Single Cell Type RNA - Adipocytes [nTPM]":"23.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"56.3","Single Cell Type RNA - Astrocytes [nTPM]":"26.1","Single Cell Type RNA - B-cells [nTPM]":"36.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"30.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"42.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.8","Single Cell Type RNA - Bipolar cells [nTPM]":"26.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"20.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"75.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"47.5","Single Cell Type RNA - dendritic cells [nTPM]":"32.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"19.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"19.5","Single Cell Type RNA - Early spermatids [nTPM]":"2.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"257.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"34.5","Single Cell Type RNA - Endothelial cells [nTPM]":"22.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"25.1","Single Cell Type RNA - Erythroid cells [nTPM]":"29.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"28.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"24.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"28.0","Single Cell Type RNA - Fibroblasts [nTPM]":"31.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"28.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"74.8","Single Cell Type RNA - granulocytes [nTPM]":"32.9","Single Cell Type RNA - Granulosa cells [nTPM]":"33.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.7","Single Cell Type RNA - Hepatocytes [nTPM]":"45.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.3","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"32.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.4","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"49.0","Single Cell Type RNA - Langerhans cells [nTPM]":"25.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.9","Single Cell Type RNA - Leydig cells [nTPM]":"19.3","Single Cell Type RNA - Macrophages [nTPM]":"44.9","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"37.5","Single Cell Type RNA - monocytes [nTPM]":"35.4","Single Cell Type RNA - Muller glia cells [nTPM]":"27.8","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"25.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"71.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.4","Single Cell Type RNA - Paneth cells [nTPM]":"20.1","Single Cell Type RNA - Peritubular cells [nTPM]":"15.1","Single Cell Type RNA - Plasma cells [nTPM]":"117.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"39.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"21.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"141.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"35.3","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.4","Single Cell Type RNA - Spermatocytes [nTPM]":"17.3","Single Cell Type RNA - Spermatogonia [nTPM]":"20.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"59.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"94.3","Single Cell Type RNA - T-cells [nTPM]":"31.8","Single Cell Type RNA - Theca cells [nTPM]":"49.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.9","Single Cell Type RNA - Urothelial cells [nTPM]":"82.0"},{"Gene":"MECOM","Gene synonym":["EVI1","KMT8E","MDS1","MDS1-EVI1","PRDM3"],"Ensembl":"ENSG00000085276","Gene description":"MDS1 and EVI1 complex locus","Uniprot":["Q03112"],"Chromosome":"3","Position":"169083499-169663775","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transcription factors"],"Biological process":["Apoptosis","Differentiation","Transcription","Transcription regulation"],"Molecular function":["Developmental protein","DNA-binding","Methyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"stomach 1":"73.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"184.8","Collecting duct cells":"125.0","Gastric mucus-secreting cells":"111.1","Glandular and luminal cells":"107.7","Microglial cells":"346.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"1.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HUVEC TERT2":"55.5","RPTEC TERT1":"71.2","RT4":"119.6","TIME":"53.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046537"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA046537":"AB_2679689"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.59e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-3"},"Tissue RNA - adipose tissue [nTPM]":"16.0","Tissue RNA - adrenal gland [nTPM]":"0.9","Tissue RNA - amygdala [nTPM]":"7.3","Tissue RNA - appendix [nTPM]":"7.3","Tissue RNA - basal ganglia [nTPM]":"7.2","Tissue RNA - bone marrow [nTPM]":"1.4","Tissue RNA - breast [nTPM]":"12.3","Tissue RNA - cerebellum [nTPM]":"8.5","Tissue RNA - cerebral cortex [nTPM]":"7.3","Tissue RNA - cervix [nTPM]":"21.3","Tissue RNA - choroid plexus [nTPM]":"2.4","Tissue RNA - colon [nTPM]":"24.9","Tissue RNA - duodenum [nTPM]":"19.8","Tissue RNA - endometrium 1 [nTPM]":"17.3","Tissue RNA - epididymis [nTPM]":"4.4","Tissue RNA - esophagus [nTPM]":"13.5","Tissue RNA - fallopian tube [nTPM]":"23.4","Tissue RNA - gallbladder [nTPM]":"8.3","Tissue RNA - heart muscle [nTPM]":"13.0","Tissue RNA - hippocampal formation [nTPM]":"4.9","Tissue RNA - hypothalamus [nTPM]":"6.3","Tissue RNA - kidney [nTPM]":"41.3","Tissue RNA - liver [nTPM]":"1.4","Tissue RNA - lung [nTPM]":"25.5","Tissue RNA - lymph node [nTPM]":"1.5","Tissue RNA - medulla oblongata [nTPM]":"9.1","Tissue RNA - midbrain [nTPM]":"7.2","Tissue RNA - ovary [nTPM]":"2.3","Tissue RNA - pancreas [nTPM]":"23.3","Tissue RNA - parathyroid gland [nTPM]":"1.7","Tissue RNA - pituitary gland [nTPM]":"4.2","Tissue RNA - placenta [nTPM]":"17.4","Tissue RNA - pons [nTPM]":"8.9","Tissue RNA - prostate [nTPM]":"6.9","Tissue RNA - rectum [nTPM]":"30.0","Tissue RNA - retina [nTPM]":"1.8","Tissue RNA - salivary gland [nTPM]":"8.8","Tissue RNA - seminal vesicle [nTPM]":"8.0","Tissue RNA - skeletal muscle [nTPM]":"4.3","Tissue RNA - skin 1 [nTPM]":"2.6","Tissue RNA - small intestine [nTPM]":"10.2","Tissue RNA - smooth muscle [nTPM]":"8.0","Tissue RNA - spinal cord [nTPM]":"4.1","Tissue RNA - spleen [nTPM]":"6.2","Tissue RNA - stomach 1 [nTPM]":"73.3","Tissue RNA - testis [nTPM]":"3.0","Tissue RNA - thalamus [nTPM]":"8.1","Tissue RNA - thymus [nTPM]":"2.0","Tissue RNA - thyroid gland [nTPM]":"5.7","Tissue RNA - tongue [nTPM]":"12.0","Tissue RNA - tonsil [nTPM]":"5.3","Tissue RNA - urinary bladder [nTPM]":"30.4","Tissue RNA - vagina [nTPM]":"7.5","Tissue RNA - white matter [nTPM]":"6.3","Cell RNA - A-431 [nTPM]":"25.8","Cell RNA - A549 [nTPM]":"0.7","Cell RNA - AF22 [nTPM]":"0.9","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"3.7","Cell RNA - ASC TERT1 [nTPM]":"2.7","Cell RNA - BEWO [nTPM]":"1.1","Cell RNA - BJ [nTPM]":"3.7","Cell RNA - BJ hTERT+ [nTPM]":"4.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.2","Cell RNA - CACO-2 [nTPM]":"10.7","Cell RNA - CAPAN-2 [nTPM]":"26.1","Cell RNA - Daudi [nTPM]":"0.9","Cell RNA - EFO-21 [nTPM]":"39.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.6","Cell RNA - GAMG [nTPM]":"5.5","Cell RNA - HaCaT [nTPM]":"13.4","Cell RNA - HAP1 [nTPM]":"10.2","Cell RNA - HBEC3-KT [nTPM]":"15.7","Cell RNA - HBF TERT88 [nTPM]":"3.1","Cell RNA - HDLM-2 [nTPM]":"1.4","Cell RNA - HEK 293 [nTPM]":"16.6","Cell RNA - HEL [nTPM]":"16.7","Cell RNA - HeLa [nTPM]":"7.6","Cell RNA - Hep G2 [nTPM]":"1.1","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"5.1","Cell RNA - HSkMC [nTPM]":"5.7","Cell RNA - hTCEpi [nTPM]":"2.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.0","Cell RNA - hTERT-HME1 [nTPM]":"12.1","Cell RNA - hTERT-RPE1 [nTPM]":"12.0","Cell RNA - HUVEC TERT2 [nTPM]":"55.5","Cell RNA - JURKAT [nTPM]":"1.4","Cell RNA - K-562 [nTPM]":"13.0","Cell RNA - Karpas-707 [nTPM]":"1.8","Cell RNA - LHCN-M2 [nTPM]":"10.3","Cell RNA - MCF7 [nTPM]":"9.8","Cell RNA - MOLT-4 [nTPM]":"0.9","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"1.7","Cell RNA - OE19 [nTPM]":"13.5","Cell RNA - PC-3 [nTPM]":"6.6","Cell RNA - REH [nTPM]":"9.8","Cell RNA - RH-30 [nTPM]":"13.1","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"71.2","Cell RNA - RT4 [nTPM]":"119.6","Cell RNA - SCLC-21H [nTPM]":"1.0","Cell RNA - SH-SY5Y [nTPM]":"3.1","Cell RNA - SiHa [nTPM]":"1.3","Cell RNA - SK-BR-3 [nTPM]":"6.7","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"1.5","Cell RNA - T-47d [nTPM]":"7.1","Cell RNA - THP-1 [nTPM]":"1.1","Cell RNA - TIME [nTPM]":"53.4","Cell RNA - U-138 MG [nTPM]":"9.7","Cell RNA - U-2 OS [nTPM]":"6.6","Cell RNA - U-2197 [nTPM]":"2.5","Cell RNA - U-251 MG [nTPM]":"16.9","Cell RNA - U-266\/70 [nTPM]":"1.4","Cell RNA - U-266\/84 [nTPM]":"0.7","Cell RNA - U-698 [nTPM]":"0.9","Cell RNA - U-87 MG [nTPM]":"4.8","Cell RNA - U-937 [nTPM]":"1.0","Cell RNA - WM-115 [nTPM]":"1.6","Blood RNA - basophil [nTPM]":"0.9","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"1.6","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"7.3","Brain RNA - basal ganglia [nTPM]":"7.2","Brain RNA - cerebellum [nTPM]":"8.5","Brain RNA - cerebral cortex [nTPM]":"7.3","Brain RNA - hippocampal formation [nTPM]":"4.9","Brain RNA - hypothalamus [nTPM]":"6.3","Brain RNA - medulla oblongata [nTPM]":"9.1","Brain RNA - midbrain [nTPM]":"7.2","Brain RNA - pons [nTPM]":"8.9","Brain RNA - spinal cord [nTPM]":"4.1","Brain RNA - thalamus [nTPM]":"8.1","Brain RNA - white matter [nTPM]":"6.3","Single Cell Type RNA - Adipocytes [nTPM]":"80.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"184.8","Single Cell Type RNA - Astrocytes [nTPM]":"16.0","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"33.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"69.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"125.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"25.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"52.8","Single Cell Type RNA - Ductal cells [nTPM]":"1.6","Single Cell Type RNA - Early spermatids [nTPM]":"10.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"71.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.8","Single Cell Type RNA - Endothelial cells [nTPM]":"70.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.9","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"75.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"4.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"111.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"107.7","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"69.3","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"29.0","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"1.9","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"2.6","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"346.6","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"13.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"49.8","Single Cell Type RNA - Paneth cells [nTPM]":"19.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"53.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.7","Single Cell Type RNA - Spermatocytes [nTPM]":"3.0","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"39.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"1.3","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"53.9","Single Cell Type RNA - Urothelial cells [nTPM]":"45.4"},{"Gene":"MECR","Gene synonym":["CGI-63","ETR1","FASN2B","NRBF1"],"Ensembl":"ENSG00000116353","Gene description":"Mitochondrial trans-2-enoyl-CoA reductase","Uniprot":["Q9BV79"],"Chromosome":"1","Position":"29192657-29230942","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Dystonia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"42.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"82.5","Rod photoreceptor cells":"68.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022018","HPA022030","HPA028740"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA022018":"AB_1853714","HPA022030":"AB_1853716","HPA028740":"AB_10601133"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.81e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.29e-4"},"Tissue RNA - adipose tissue [nTPM]":"14.7","Tissue RNA - adrenal gland [nTPM]":"14.6","Tissue RNA - amygdala [nTPM]":"5.1","Tissue RNA - appendix [nTPM]":"1.7","Tissue RNA - basal ganglia [nTPM]":"5.1","Tissue RNA - bone marrow [nTPM]":"1.8","Tissue RNA - breast [nTPM]":"13.4","Tissue RNA - cerebellum [nTPM]":"3.3","Tissue RNA - cerebral cortex [nTPM]":"6.2","Tissue RNA - cervix [nTPM]":"10.2","Tissue RNA - choroid plexus [nTPM]":"3.1","Tissue RNA - colon [nTPM]":"10.3","Tissue RNA - duodenum [nTPM]":"1.4","Tissue RNA - endometrium 1 [nTPM]":"12.9","Tissue RNA - epididymis [nTPM]":"2.5","Tissue RNA - esophagus [nTPM]":"12.5","Tissue RNA - fallopian tube [nTPM]":"9.4","Tissue RNA - gallbladder [nTPM]":"1.3","Tissue RNA - heart muscle [nTPM]":"24.8","Tissue RNA - hippocampal formation [nTPM]":"6.0","Tissue RNA - hypothalamus [nTPM]":"3.9","Tissue RNA - kidney [nTPM]":"14.1","Tissue RNA - liver [nTPM]":"15.8","Tissue RNA - lung [nTPM]":"7.3","Tissue RNA - lymph node [nTPM]":"2.0","Tissue RNA - medulla oblongata [nTPM]":"5.2","Tissue RNA - midbrain [nTPM]":"4.0","Tissue RNA - ovary [nTPM]":"10.0","Tissue RNA - pancreas [nTPM]":"8.9","Tissue RNA - parathyroid gland [nTPM]":"4.5","Tissue RNA - pituitary gland [nTPM]":"7.2","Tissue RNA - placenta [nTPM]":"3.5","Tissue RNA - pons [nTPM]":"5.4","Tissue RNA - prostate [nTPM]":"7.9","Tissue RNA - rectum [nTPM]":"2.6","Tissue RNA - retina [nTPM]":"9.9","Tissue RNA - salivary gland [nTPM]":"12.3","Tissue RNA - seminal vesicle [nTPM]":"3.0","Tissue RNA - skeletal muscle [nTPM]":"42.1","Tissue RNA - skin 1 [nTPM]":"15.4","Tissue RNA - small intestine [nTPM]":"7.2","Tissue RNA - smooth muscle [nTPM]":"3.1","Tissue RNA - spinal cord [nTPM]":"3.2","Tissue RNA - spleen [nTPM]":"6.7","Tissue RNA - stomach 1 [nTPM]":"11.1","Tissue RNA - testis [nTPM]":"7.6","Tissue RNA - thalamus [nTPM]":"4.3","Tissue RNA - thymus [nTPM]":"1.4","Tissue RNA - thyroid gland [nTPM]":"8.3","Tissue RNA - tongue [nTPM]":"5.8","Tissue RNA - tonsil [nTPM]":"2.1","Tissue RNA - urinary bladder [nTPM]":"9.6","Tissue RNA - vagina [nTPM]":"9.6","Tissue RNA - white matter [nTPM]":"5.2","Cell RNA - A-431 [nTPM]":"3.9","Cell RNA - A549 [nTPM]":"4.5","Cell RNA - AF22 [nTPM]":"3.2","Cell RNA - AN3-CA [nTPM]":"4.6","Cell RNA - ASC diff [nTPM]":"2.9","Cell RNA - ASC TERT1 [nTPM]":"2.5","Cell RNA - BEWO [nTPM]":"6.8","Cell RNA - BJ [nTPM]":"3.7","Cell RNA - BJ hTERT+ [nTPM]":"3.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.9","Cell RNA - CACO-2 [nTPM]":"2.3","Cell RNA - CAPAN-2 [nTPM]":"5.6","Cell RNA - Daudi [nTPM]":"7.3","Cell RNA - EFO-21 [nTPM]":"5.1","Cell RNA - fHDF\/TERT166 [nTPM]":"3.7","Cell RNA - GAMG [nTPM]":"1.3","Cell RNA - HaCaT [nTPM]":"3.0","Cell RNA - HAP1 [nTPM]":"5.4","Cell RNA - HBEC3-KT [nTPM]":"6.3","Cell RNA - HBF TERT88 [nTPM]":"4.0","Cell RNA - HDLM-2 [nTPM]":"4.4","Cell RNA - HEK 293 [nTPM]":"6.9","Cell RNA - HEL [nTPM]":"6.4","Cell RNA - HeLa [nTPM]":"3.4","Cell RNA - Hep G2 [nTPM]":"4.1","Cell RNA - HHSteC [nTPM]":"6.6","Cell RNA - HL-60 [nTPM]":"6.1","Cell RNA - HMC-1 [nTPM]":"1.9","Cell RNA - HSkMC [nTPM]":"4.3","Cell RNA - hTCEpi [nTPM]":"5.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.1","Cell RNA - hTERT-HME1 [nTPM]":"11.0","Cell RNA - hTERT-RPE1 [nTPM]":"3.8","Cell RNA - HUVEC TERT2 [nTPM]":"3.5","Cell RNA - JURKAT [nTPM]":"6.9","Cell RNA - K-562 [nTPM]":"5.8","Cell RNA - Karpas-707 [nTPM]":"4.2","Cell RNA - LHCN-M2 [nTPM]":"4.7","Cell RNA - MCF7 [nTPM]":"4.5","Cell RNA - MOLT-4 [nTPM]":"3.9","Cell RNA - NB-4 [nTPM]":"2.9","Cell RNA - NTERA-2 [nTPM]":"6.5","Cell RNA - OE19 [nTPM]":"5.8","Cell RNA - PC-3 [nTPM]":"4.3","Cell RNA - REH [nTPM]":"3.5","Cell RNA - RH-30 [nTPM]":"4.2","Cell RNA - RPMI-8226 [nTPM]":"9.3","Cell RNA - RPTEC TERT1 [nTPM]":"5.9","Cell RNA - RT4 [nTPM]":"2.4","Cell RNA - SCLC-21H [nTPM]":"5.1","Cell RNA - SH-SY5Y [nTPM]":"4.5","Cell RNA - SiHa [nTPM]":"4.1","Cell RNA - SK-BR-3 [nTPM]":"4.7","Cell RNA - SK-MEL-30 [nTPM]":"7.0","Cell RNA - SuSa [nTPM]":"4.4","Cell RNA - T-47d [nTPM]":"2.3","Cell RNA - THP-1 [nTPM]":"5.4","Cell RNA - TIME [nTPM]":"3.8","Cell RNA - U-138 MG [nTPM]":"2.4","Cell RNA - U-2 OS [nTPM]":"2.9","Cell RNA - U-2197 [nTPM]":"4.1","Cell RNA - U-251 MG [nTPM]":"4.7","Cell RNA - U-266\/70 [nTPM]":"2.7","Cell RNA - U-266\/84 [nTPM]":"2.2","Cell RNA - U-698 [nTPM]":"5.0","Cell RNA - U-87 MG [nTPM]":"3.9","Cell RNA - U-937 [nTPM]":"8.4","Cell RNA - WM-115 [nTPM]":"5.2","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"2.2","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"2.1","Blood RNA - MAIT T-cell [nTPM]":"4.1","Blood RNA - memory B-cell [nTPM]":"2.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.6","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"1.9","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"2.3","Blood RNA - naive CD8 T-cell [nTPM]":"1.6","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"2.9","Blood RNA - non-classical monocyte [nTPM]":"1.6","Blood RNA - plasmacytoid DC [nTPM]":"2.5","Blood RNA - T-reg [nTPM]":"2.4","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"5.1","Brain RNA - basal ganglia [nTPM]":"5.1","Brain RNA - cerebellum [nTPM]":"3.3","Brain RNA - cerebral cortex [nTPM]":"6.2","Brain RNA - hippocampal formation [nTPM]":"6.0","Brain RNA - hypothalamus [nTPM]":"3.9","Brain RNA - medulla oblongata [nTPM]":"5.2","Brain RNA - midbrain [nTPM]":"4.0","Brain RNA - pons [nTPM]":"5.4","Brain RNA - spinal cord [nTPM]":"3.2","Brain RNA - thalamus [nTPM]":"4.3","Brain RNA - white matter [nTPM]":"5.2","Single Cell Type RNA - Adipocytes [nTPM]":"8.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.9","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"9.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"26.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"12.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"21.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"46.0","Single Cell Type RNA - dendritic cells [nTPM]":"3.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"41.1","Single Cell Type RNA - Ductal cells [nTPM]":"24.3","Single Cell Type RNA - Early spermatids [nTPM]":"40.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.6","Single Cell Type RNA - Endothelial cells [nTPM]":"9.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.8","Single Cell Type RNA - Erythroid cells [nTPM]":"10.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"42.4","Single Cell Type RNA - Fibroblasts [nTPM]":"12.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.8","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"17.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.1","Single Cell Type RNA - Hepatocytes [nTPM]":"19.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.8","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.4","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"6.0","Single Cell Type RNA - Langerhans cells [nTPM]":"5.1","Single Cell Type RNA - Late spermatids [nTPM]":"82.5","Single Cell Type RNA - Leydig cells [nTPM]":"13.7","Single Cell Type RNA - Macrophages [nTPM]":"5.3","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"10.8","Single Cell Type RNA - Muller glia cells [nTPM]":"14.5","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.3","Single Cell Type RNA - Paneth cells [nTPM]":"8.0","Single Cell Type RNA - Peritubular cells [nTPM]":"10.9","Single Cell Type RNA - Plasma cells [nTPM]":"10.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"46.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"68.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.9","Single Cell Type RNA - Spermatocytes [nTPM]":"8.5","Single Cell Type RNA - Spermatogonia [nTPM]":"16.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"27.9","Single Cell Type RNA - T-cells [nTPM]":"6.0","Single Cell Type RNA - Theca cells [nTPM]":"25.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.3","Single Cell Type RNA - Urothelial cells [nTPM]":"20.5"},{"Gene":"MELK","Gene synonym":["KIAA0175"],"Ensembl":"ENSG00000165304","Gene description":"Maternal embryonic leucine zipper kinase","Uniprot":["Q14680"],"Chromosome":"9","Position":"36572862-36677683","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Cell cycle"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"10.0","lymphoid tissue":"21.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"16.1","Erythroid cells":"15.2","Extravillous trophoblasts":"44.1","Spermatocytes":"23.2","Spermatogonia":"21.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"T-reg":"1.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"T-cells":"1.7"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017214"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017214":"AB_1853798"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.57e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.91e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.99e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.58e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.86e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.9","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"5.7","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"10.0","Tissue RNA - breast [nTPM]":"1.4","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"1.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"6.8","Tissue RNA - duodenum [nTPM]":"5.2","Tissue RNA - endometrium 1 [nTPM]":"1.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"7.9","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.6","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.7","Tissue RNA - lung [nTPM]":"0.9","Tissue RNA - lymph node [nTPM]":"10.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"5.3","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"8.5","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"1.2","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"3.4","Tissue RNA - small intestine [nTPM]":"4.4","Tissue RNA - smooth muscle [nTPM]":"2.4","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"2.0","Tissue RNA - stomach 1 [nTPM]":"3.2","Tissue RNA - testis [nTPM]":"9.2","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"21.0","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"11.7","Tissue RNA - urinary bladder [nTPM]":"1.7","Tissue RNA - vagina [nTPM]":"2.3","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"123.4","Cell RNA - A549 [nTPM]":"62.1","Cell RNA - AF22 [nTPM]":"81.6","Cell RNA - AN3-CA [nTPM]":"48.5","Cell RNA - ASC diff [nTPM]":"11.1","Cell RNA - ASC TERT1 [nTPM]":"18.8","Cell RNA - BEWO [nTPM]":"47.1","Cell RNA - BJ [nTPM]":"88.8","Cell RNA - BJ hTERT+ [nTPM]":"62.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"121.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"148.2","Cell RNA - CACO-2 [nTPM]":"47.8","Cell RNA - CAPAN-2 [nTPM]":"47.3","Cell RNA - Daudi [nTPM]":"40.9","Cell RNA - EFO-21 [nTPM]":"27.8","Cell RNA - fHDF\/TERT166 [nTPM]":"43.8","Cell RNA - GAMG [nTPM]":"106.5","Cell RNA - HaCaT [nTPM]":"41.0","Cell RNA - HAP1 [nTPM]":"71.7","Cell RNA - HBEC3-KT [nTPM]":"55.5","Cell RNA - HBF TERT88 [nTPM]":"133.1","Cell RNA - HDLM-2 [nTPM]":"112.3","Cell RNA - HEK 293 [nTPM]":"28.6","Cell RNA - HEL [nTPM]":"32.0","Cell RNA - HeLa [nTPM]":"69.1","Cell RNA - Hep G2 [nTPM]":"48.1","Cell RNA - HHSteC [nTPM]":"4.3","Cell RNA - HL-60 [nTPM]":"50.2","Cell RNA - HMC-1 [nTPM]":"39.0","Cell RNA - HSkMC [nTPM]":"6.9","Cell RNA - hTCEpi [nTPM]":"9.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"93.9","Cell RNA - hTERT-HME1 [nTPM]":"53.0","Cell RNA - hTERT-RPE1 [nTPM]":"15.6","Cell RNA - HUVEC TERT2 [nTPM]":"62.2","Cell RNA - JURKAT [nTPM]":"61.9","Cell RNA - K-562 [nTPM]":"41.7","Cell RNA - Karpas-707 [nTPM]":"63.2","Cell RNA - LHCN-M2 [nTPM]":"100.9","Cell RNA - MCF7 [nTPM]":"40.9","Cell RNA - MOLT-4 [nTPM]":"63.1","Cell RNA - NB-4 [nTPM]":"23.4","Cell RNA - NTERA-2 [nTPM]":"65.1","Cell RNA - OE19 [nTPM]":"55.1","Cell RNA - PC-3 [nTPM]":"47.9","Cell RNA - REH [nTPM]":"57.4","Cell RNA - RH-30 [nTPM]":"54.9","Cell RNA - RPMI-8226 [nTPM]":"25.8","Cell RNA - RPTEC TERT1 [nTPM]":"37.7","Cell RNA - RT4 [nTPM]":"40.7","Cell RNA - SCLC-21H [nTPM]":"55.1","Cell RNA - SH-SY5Y [nTPM]":"40.8","Cell RNA - SiHa [nTPM]":"47.4","Cell RNA - SK-BR-3 [nTPM]":"45.3","Cell RNA - SK-MEL-30 [nTPM]":"28.6","Cell RNA - SuSa [nTPM]":"45.2","Cell RNA - T-47d [nTPM]":"38.0","Cell RNA - THP-1 [nTPM]":"23.7","Cell RNA - TIME [nTPM]":"30.8","Cell RNA - U-138 MG [nTPM]":"65.4","Cell RNA - U-2 OS [nTPM]":"81.8","Cell RNA - U-2197 [nTPM]":"56.1","Cell RNA - U-251 MG [nTPM]":"82.3","Cell RNA - U-266\/70 [nTPM]":"12.3","Cell RNA - U-266\/84 [nTPM]":"47.9","Cell RNA - U-698 [nTPM]":"60.7","Cell RNA - U-87 MG [nTPM]":"41.2","Cell RNA - U-937 [nTPM]":"36.8","Cell RNA - WM-115 [nTPM]":"91.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"1.7","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"1.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.1","Single Cell Type RNA - Early spermatids [nTPM]":"2.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.4","Single Cell Type RNA - Endothelial cells [nTPM]":"1.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"15.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"44.1","Single Cell Type RNA - Fibroblasts [nTPM]":"3.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"7.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.7","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"3.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.7","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"1.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"3.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.7","Single Cell Type RNA - Paneth cells [nTPM]":"2.7","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"10.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.7","Single Cell Type RNA - Spermatocytes [nTPM]":"23.2","Single Cell Type RNA - Spermatogonia [nTPM]":"21.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.9","Single Cell Type RNA - T-cells [nTPM]":"2.7","Single Cell Type RNA - Theca cells [nTPM]":"0.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.9","Single Cell Type RNA - Urothelial cells [nTPM]":"2.3"},{"Gene":"MERTK","Gene synonym":["c-Eyk","mer","RP38","Tyro12"],"Ensembl":"ENSG00000153208","Gene description":"MER proto-oncogene, tyrosine kinase","Uniprot":["Q12866"],"Chromosome":"2","Position":"111898607-112029561","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Disease variant","Proto-oncogene","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"162.6","Kupffer cells":"119.8","Macrophages":"46.5","Microglial cells":"124.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"12","RNA blood cell specific nTPM":{"intermediate monocyte":"8.6","non-classical monocyte":"5.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"50","RNA blood lineage specific nTPM":{"monocytes":"8.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"35.1","Hep G2":"39.9","HUVEC TERT2":"38.4","RT4":"23.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036196","HPA075622"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Plasma membrane","Midbody","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"65000000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Endoplasmic reticulum","Midbody","Cytosol"],"Antibody RRID":{"HPA036196":"AB_10670676","HPA075622":"AB_2686759"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.74e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.43e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Tissue RNA - adipose tissue [nTPM]":"20.1","Tissue RNA - adrenal gland [nTPM]":"59.8","Tissue RNA - amygdala [nTPM]":"22.8","Tissue RNA - appendix [nTPM]":"13.5","Tissue RNA - basal ganglia [nTPM]":"28.0","Tissue RNA - bone marrow [nTPM]":"1.5","Tissue RNA - breast [nTPM]":"15.3","Tissue RNA - cerebellum [nTPM]":"18.0","Tissue RNA - cerebral cortex [nTPM]":"29.3","Tissue RNA - cervix [nTPM]":"12.6","Tissue RNA - choroid plexus [nTPM]":"44.7","Tissue RNA - colon [nTPM]":"10.9","Tissue RNA - duodenum [nTPM]":"12.3","Tissue RNA - endometrium 1 [nTPM]":"11.5","Tissue RNA - epididymis [nTPM]":"26.3","Tissue RNA - esophagus [nTPM]":"8.4","Tissue RNA - fallopian tube [nTPM]":"15.5","Tissue RNA - gallbladder [nTPM]":"12.0","Tissue RNA - heart muscle [nTPM]":"7.0","Tissue RNA - hippocampal formation [nTPM]":"22.0","Tissue RNA - hypothalamus [nTPM]":"22.5","Tissue RNA - kidney [nTPM]":"11.4","Tissue RNA - liver [nTPM]":"21.0","Tissue RNA - lung [nTPM]":"13.6","Tissue RNA - lymph node [nTPM]":"13.1","Tissue RNA - medulla oblongata [nTPM]":"23.5","Tissue RNA - midbrain [nTPM]":"22.3","Tissue RNA - ovary [nTPM]":"12.6","Tissue RNA - pancreas [nTPM]":"9.9","Tissue RNA - parathyroid gland [nTPM]":"21.2","Tissue RNA - pituitary gland [nTPM]":"15.5","Tissue RNA - placenta [nTPM]":"20.1","Tissue RNA - pons [nTPM]":"22.4","Tissue RNA - prostate [nTPM]":"14.1","Tissue RNA - rectum [nTPM]":"7.9","Tissue RNA - retina [nTPM]":"16.6","Tissue RNA - salivary gland [nTPM]":"6.4","Tissue RNA - seminal vesicle [nTPM]":"16.3","Tissue RNA - skeletal muscle [nTPM]":"3.2","Tissue RNA - skin 1 [nTPM]":"6.4","Tissue RNA - small intestine [nTPM]":"14.3","Tissue RNA - smooth muscle [nTPM]":"14.4","Tissue RNA - spinal cord [nTPM]":"18.4","Tissue RNA - spleen [nTPM]":"30.6","Tissue RNA - stomach 1 [nTPM]":"13.9","Tissue RNA - testis [nTPM]":"17.2","Tissue RNA - thalamus [nTPM]":"30.1","Tissue RNA - thymus [nTPM]":"6.8","Tissue RNA - thyroid gland [nTPM]":"10.1","Tissue RNA - tongue [nTPM]":"4.6","Tissue RNA - tonsil [nTPM]":"8.9","Tissue RNA - urinary bladder [nTPM]":"13.6","Tissue RNA - vagina [nTPM]":"9.4","Tissue RNA - white matter [nTPM]":"22.0","Cell RNA - A-431 [nTPM]":"1.0","Cell RNA - A549 [nTPM]":"1.7","Cell RNA - AF22 [nTPM]":"7.6","Cell RNA - AN3-CA [nTPM]":"17.3","Cell RNA - ASC diff [nTPM]":"0.4","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"12.3","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.7","Cell RNA - CACO-2 [nTPM]":"35.1","Cell RNA - CAPAN-2 [nTPM]":"2.2","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"8.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"7.9","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"10.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"1.4","Cell RNA - HDLM-2 [nTPM]":"1.5","Cell RNA - HEK 293 [nTPM]":"5.5","Cell RNA - HEL [nTPM]":"7.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"39.9","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"1.5","Cell RNA - HSkMC [nTPM]":"0.5","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.9","Cell RNA - hTERT-HME1 [nTPM]":"0.6","Cell RNA - hTERT-RPE1 [nTPM]":"4.0","Cell RNA - HUVEC TERT2 [nTPM]":"38.4","Cell RNA - JURKAT [nTPM]":"1.5","Cell RNA - K-562 [nTPM]":"2.2","Cell RNA - Karpas-707 [nTPM]":"3.5","Cell RNA - LHCN-M2 [nTPM]":"2.9","Cell RNA - MCF7 [nTPM]":"1.8","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"9.1","Cell RNA - NTERA-2 [nTPM]":"4.8","Cell RNA - OE19 [nTPM]":"1.1","Cell RNA - PC-3 [nTPM]":"6.0","Cell RNA - REH [nTPM]":"2.9","Cell RNA - RH-30 [nTPM]":"2.1","Cell RNA - RPMI-8226 [nTPM]":"3.0","Cell RNA - RPTEC TERT1 [nTPM]":"19.4","Cell RNA - RT4 [nTPM]":"23.4","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"7.2","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"3.2","Cell RNA - SuSa [nTPM]":"2.7","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"5.8","Cell RNA - U-138 MG [nTPM]":"1.0","Cell RNA - U-2 OS [nTPM]":"3.4","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"3.1","Cell RNA - U-266\/84 [nTPM]":"4.8","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"1.4","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"8.6","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"5.5","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"22.8","Brain RNA - basal ganglia [nTPM]":"28.0","Brain RNA - cerebellum [nTPM]":"18.0","Brain RNA - cerebral cortex [nTPM]":"29.3","Brain RNA - hippocampal formation [nTPM]":"22.0","Brain RNA - hypothalamus [nTPM]":"22.5","Brain RNA - medulla oblongata [nTPM]":"23.5","Brain RNA - midbrain [nTPM]":"22.3","Brain RNA - pons [nTPM]":"22.4","Brain RNA - spinal cord [nTPM]":"18.4","Brain RNA - thalamus [nTPM]":"30.1","Brain RNA - white matter [nTPM]":"22.0","Single Cell Type RNA - Adipocytes [nTPM]":"8.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.7","Single Cell Type RNA - Astrocytes [nTPM]":"162.6","Single Cell Type RNA - B-cells [nTPM]":"1.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"6.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.1","Single Cell Type RNA - Early spermatids [nTPM]":"2.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.7","Single Cell Type RNA - Endothelial cells [nTPM]":"10.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.1","Single Cell Type RNA - Fibroblasts [nTPM]":"3.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.5","Single Cell Type RNA - Hepatocytes [nTPM]":"9.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"119.8","Single Cell Type RNA - Langerhans cells [nTPM]":"1.8","Single Cell Type RNA - Late spermatids [nTPM]":"2.7","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"46.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"124.6","Single Cell Type RNA - monocytes [nTPM]":"1.5","Single Cell Type RNA - Muller glia cells [nTPM]":"7.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.2","Single Cell Type RNA - Paneth cells [nTPM]":"1.9","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"10.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"1.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"18.9","Single Cell Type RNA - T-cells [nTPM]":"1.3","Single Cell Type RNA - Theca cells [nTPM]":"3.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.9","Single Cell Type RNA - Urothelial cells [nTPM]":"1.6"},{"Gene":"MEX3C","Gene synonym":["FLJ38871","RKHD2","RNF194"],"Ensembl":"ENSG00000176624","Gene description":"Mex-3 RNA binding family member C","Uniprot":["Q5U5Q3"],"Chromosome":"18","Position":"51174550-51218333","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["RNA-binding","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"118.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Early spermatids":"555.3","Late spermatids":"514.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"9.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040603"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA040603":"AB_10805714"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.49e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Tissue RNA - adipose tissue [nTPM]":"17.6","Tissue RNA - adrenal gland [nTPM]":"13.5","Tissue RNA - amygdala [nTPM]":"9.1","Tissue RNA - appendix [nTPM]":"17.0","Tissue RNA - basal ganglia [nTPM]":"9.9","Tissue RNA - bone marrow [nTPM]":"49.4","Tissue RNA - breast [nTPM]":"17.4","Tissue RNA - cerebellum [nTPM]":"12.5","Tissue RNA - cerebral cortex [nTPM]":"12.3","Tissue RNA - cervix [nTPM]":"16.4","Tissue RNA - choroid plexus [nTPM]":"9.0","Tissue RNA - colon [nTPM]":"13.5","Tissue RNA - duodenum [nTPM]":"12.6","Tissue RNA - endometrium 1 [nTPM]":"17.6","Tissue RNA - epididymis [nTPM]":"10.4","Tissue RNA - esophagus [nTPM]":"15.5","Tissue RNA - fallopian tube [nTPM]":"14.0","Tissue RNA - gallbladder [nTPM]":"18.6","Tissue RNA - heart muscle [nTPM]":"10.8","Tissue RNA - hippocampal formation [nTPM]":"10.5","Tissue RNA - hypothalamus [nTPM]":"9.8","Tissue RNA - kidney [nTPM]":"11.9","Tissue RNA - liver [nTPM]":"14.0","Tissue RNA - lung [nTPM]":"13.7","Tissue RNA - lymph node [nTPM]":"23.6","Tissue RNA - medulla oblongata [nTPM]":"10.5","Tissue RNA - midbrain [nTPM]":"10.0","Tissue RNA - ovary [nTPM]":"23.5","Tissue RNA - pancreas [nTPM]":"14.7","Tissue RNA - parathyroid gland [nTPM]":"17.9","Tissue RNA - pituitary gland [nTPM]":"1.7","Tissue RNA - placenta [nTPM]":"16.1","Tissue RNA - pons [nTPM]":"10.6","Tissue RNA - prostate [nTPM]":"11.5","Tissue RNA - rectum [nTPM]":"14.1","Tissue RNA - retina [nTPM]":"14.8","Tissue RNA - salivary gland [nTPM]":"9.6","Tissue RNA - seminal vesicle [nTPM]":"12.2","Tissue RNA - skeletal muscle [nTPM]":"9.7","Tissue RNA - skin 1 [nTPM]":"9.2","Tissue RNA - small intestine [nTPM]":"13.4","Tissue RNA - smooth muscle [nTPM]":"20.1","Tissue RNA - spinal cord [nTPM]":"10.7","Tissue RNA - spleen [nTPM]":"22.3","Tissue RNA - stomach 1 [nTPM]":"13.3","Tissue RNA - testis [nTPM]":"118.4","Tissue RNA - thalamus [nTPM]":"9.3","Tissue RNA - thymus [nTPM]":"40.9","Tissue RNA - thyroid gland [nTPM]":"16.1","Tissue RNA - tongue [nTPM]":"17.1","Tissue RNA - tonsil [nTPM]":"26.6","Tissue RNA - urinary bladder [nTPM]":"20.2","Tissue RNA - vagina [nTPM]":"2.4","Tissue RNA - white matter [nTPM]":"11.6","Cell RNA - A-431 [nTPM]":"23.8","Cell RNA - A549 [nTPM]":"19.6","Cell RNA - AF22 [nTPM]":"71.2","Cell RNA - AN3-CA [nTPM]":"26.8","Cell RNA - ASC diff [nTPM]":"27.7","Cell RNA - ASC TERT1 [nTPM]":"36.8","Cell RNA - BEWO [nTPM]":"49.6","Cell RNA - BJ [nTPM]":"32.8","Cell RNA - BJ hTERT+ [nTPM]":"37.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"22.2","Cell RNA - CACO-2 [nTPM]":"33.6","Cell RNA - CAPAN-2 [nTPM]":"17.3","Cell RNA - Daudi [nTPM]":"53.0","Cell RNA - EFO-21 [nTPM]":"13.2","Cell RNA - fHDF\/TERT166 [nTPM]":"44.2","Cell RNA - GAMG [nTPM]":"30.4","Cell RNA - HaCaT [nTPM]":"44.6","Cell RNA - HAP1 [nTPM]":"27.9","Cell RNA - HBEC3-KT [nTPM]":"42.7","Cell RNA - HBF TERT88 [nTPM]":"31.0","Cell RNA - HDLM-2 [nTPM]":"43.0","Cell RNA - HEK 293 [nTPM]":"12.5","Cell RNA - HEL [nTPM]":"10.7","Cell RNA - HeLa [nTPM]":"19.1","Cell RNA - Hep G2 [nTPM]":"29.0","Cell RNA - HHSteC [nTPM]":"44.5","Cell RNA - HL-60 [nTPM]":"75.2","Cell RNA - HMC-1 [nTPM]":"22.3","Cell RNA - HSkMC [nTPM]":"28.2","Cell RNA - hTCEpi [nTPM]":"46.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.9","Cell RNA - hTERT-HME1 [nTPM]":"76.4","Cell RNA - hTERT-RPE1 [nTPM]":"47.0","Cell RNA - HUVEC TERT2 [nTPM]":"41.8","Cell RNA - JURKAT [nTPM]":"36.0","Cell RNA - K-562 [nTPM]":"11.3","Cell RNA - Karpas-707 [nTPM]":"95.7","Cell RNA - LHCN-M2 [nTPM]":"40.0","Cell RNA - MCF7 [nTPM]":"18.0","Cell RNA - MOLT-4 [nTPM]":"63.8","Cell RNA - NB-4 [nTPM]":"24.3","Cell RNA - NTERA-2 [nTPM]":"32.1","Cell RNA - OE19 [nTPM]":"13.3","Cell RNA - PC-3 [nTPM]":"15.0","Cell RNA - REH [nTPM]":"61.7","Cell RNA - RH-30 [nTPM]":"36.5","Cell RNA - RPMI-8226 [nTPM]":"46.7","Cell RNA - RPTEC TERT1 [nTPM]":"31.1","Cell RNA - RT4 [nTPM]":"9.5","Cell RNA - SCLC-21H [nTPM]":"34.8","Cell RNA - SH-SY5Y [nTPM]":"39.1","Cell RNA - SiHa [nTPM]":"30.4","Cell RNA - SK-BR-3 [nTPM]":"12.4","Cell RNA - SK-MEL-30 [nTPM]":"117.7","Cell RNA - SuSa [nTPM]":"54.3","Cell RNA - T-47d [nTPM]":"13.5","Cell RNA - THP-1 [nTPM]":"34.3","Cell RNA - TIME [nTPM]":"43.2","Cell RNA - U-138 MG [nTPM]":"46.3","Cell RNA - U-2 OS [nTPM]":"30.9","Cell RNA - U-2197 [nTPM]":"15.1","Cell RNA - U-251 MG [nTPM]":"28.1","Cell RNA - U-266\/70 [nTPM]":"64.5","Cell RNA - U-266\/84 [nTPM]":"12.4","Cell RNA - U-698 [nTPM]":"87.2","Cell RNA - U-87 MG [nTPM]":"32.9","Cell RNA - U-937 [nTPM]":"31.3","Cell RNA - WM-115 [nTPM]":"110.7","Blood RNA - basophil [nTPM]":"9.7","Blood RNA - classical monocyte [nTPM]":"1.2","Blood RNA - eosinophil [nTPM]":"1.5","Blood RNA - gdT-cell [nTPM]":"2.3","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"2.0","Blood RNA - memory B-cell [nTPM]":"1.9","Blood RNA - memory CD4 T-cell [nTPM]":"2.4","Blood RNA - memory CD8 T-cell [nTPM]":"2.4","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.9","Blood RNA - naive CD8 T-cell [nTPM]":"2.3","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"3.4","Blood RNA - non-classical monocyte [nTPM]":"0.7","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"2.0","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"9.1","Brain RNA - basal ganglia [nTPM]":"9.9","Brain RNA - cerebellum [nTPM]":"12.5","Brain RNA - cerebral cortex [nTPM]":"12.3","Brain RNA - hippocampal formation [nTPM]":"10.5","Brain RNA - hypothalamus [nTPM]":"9.8","Brain RNA - medulla oblongata [nTPM]":"10.5","Brain RNA - midbrain [nTPM]":"10.0","Brain RNA - pons [nTPM]":"10.6","Brain RNA - spinal cord [nTPM]":"10.7","Brain RNA - thalamus [nTPM]":"9.3","Brain RNA - white matter [nTPM]":"11.6","Single Cell Type RNA - Adipocytes [nTPM]":"25.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.0","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"18.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"38.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"12.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"11.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.2","Single Cell Type RNA - dendritic cells [nTPM]":"56.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"12.1","Single Cell Type RNA - Early spermatids [nTPM]":"555.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.7","Single Cell Type RNA - Endothelial cells [nTPM]":"30.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.0","Single Cell Type RNA - Fibroblasts [nTPM]":"18.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"34.9","Single Cell Type RNA - granulocytes [nTPM]":"12.7","Single Cell Type RNA - Granulosa cells [nTPM]":"79.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.4","Single Cell Type RNA - Hepatocytes [nTPM]":"7.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.7","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.4","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"10.9","Single Cell Type RNA - Langerhans cells [nTPM]":"20.5","Single Cell Type RNA - Late spermatids [nTPM]":"514.0","Single Cell Type RNA - Leydig cells [nTPM]":"16.1","Single Cell Type RNA - Macrophages [nTPM]":"13.8","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"8.2","Single Cell Type RNA - Muller glia cells [nTPM]":"10.0","Single Cell Type RNA - NK-cells [nTPM]":"34.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"13.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.5","Single Cell Type RNA - Paneth cells [nTPM]":"3.9","Single Cell Type RNA - Peritubular cells [nTPM]":"15.1","Single Cell Type RNA - Plasma cells [nTPM]":"20.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.7","Single Cell Type RNA - Spermatocytes [nTPM]":"14.4","Single Cell Type RNA - Spermatogonia [nTPM]":"14.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"45.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.2","Single Cell Type RNA - T-cells [nTPM]":"24.2","Single Cell Type RNA - Theca cells [nTPM]":"14.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.5","Single Cell Type RNA - Urothelial cells [nTPM]":"19.6"},{"Gene":"MFN2","Gene synonym":["CMT2A2","CPRP1","KIAA0214","MARF"],"Ensembl":"ENSG00000116688","Gene description":"Mitofusin 2","Uniprot":["O95140"],"Chromosome":"1","Position":"11980181-12015211","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Autophagy","Unfolded protein response"],"Molecular function":["Hydrolase"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"270.4","skeletal muscle":"310.5","tongue":"337.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Cardiomyocytes":"336.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030554","CAB079902"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB079902":"AB_2724683","HPA030554":"AB_10603018"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.36e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Tissue RNA - adipose tissue [nTPM]":"34.7","Tissue RNA - adrenal gland [nTPM]":"31.4","Tissue RNA - amygdala [nTPM]":"39.9","Tissue RNA - appendix [nTPM]":"20.9","Tissue RNA - basal ganglia [nTPM]":"42.4","Tissue RNA - bone marrow [nTPM]":"26.7","Tissue RNA - breast [nTPM]":"31.8","Tissue RNA - cerebellum [nTPM]":"39.1","Tissue RNA - cerebral cortex [nTPM]":"41.4","Tissue RNA - cervix [nTPM]":"29.3","Tissue RNA - choroid plexus [nTPM]":"17.4","Tissue RNA - colon [nTPM]":"59.7","Tissue RNA - duodenum [nTPM]":"41.9","Tissue RNA - endometrium 1 [nTPM]":"37.0","Tissue RNA - epididymis [nTPM]":"12.7","Tissue RNA - esophagus [nTPM]":"57.3","Tissue RNA - fallopian tube [nTPM]":"26.2","Tissue RNA - gallbladder [nTPM]":"21.8","Tissue RNA - heart muscle [nTPM]":"270.4","Tissue RNA - hippocampal formation [nTPM]":"34.7","Tissue RNA - hypothalamus [nTPM]":"43.0","Tissue RNA - kidney [nTPM]":"36.5","Tissue RNA - liver [nTPM]":"58.5","Tissue RNA - lung [nTPM]":"31.1","Tissue RNA - lymph node [nTPM]":"19.8","Tissue RNA - medulla oblongata [nTPM]":"41.1","Tissue RNA - midbrain [nTPM]":"44.8","Tissue RNA - ovary [nTPM]":"27.0","Tissue RNA - pancreas [nTPM]":"22.5","Tissue RNA - parathyroid gland [nTPM]":"76.7","Tissue RNA - pituitary gland [nTPM]":"28.7","Tissue RNA - placenta [nTPM]":"27.6","Tissue RNA - pons [nTPM]":"40.6","Tissue RNA - prostate [nTPM]":"36.3","Tissue RNA - rectum [nTPM]":"38.1","Tissue RNA - retina [nTPM]":"35.0","Tissue RNA - salivary gland [nTPM]":"32.2","Tissue RNA - seminal vesicle [nTPM]":"62.3","Tissue RNA - skeletal muscle [nTPM]":"310.5","Tissue RNA - skin 1 [nTPM]":"58.9","Tissue RNA - small intestine [nTPM]":"46.3","Tissue RNA - smooth muscle [nTPM]":"41.2","Tissue RNA - spinal cord [nTPM]":"43.5","Tissue RNA - spleen [nTPM]":"31.5","Tissue RNA - stomach 1 [nTPM]":"44.9","Tissue RNA - testis [nTPM]":"25.4","Tissue RNA - thalamus [nTPM]":"48.8","Tissue RNA - thymus [nTPM]":"26.1","Tissue RNA - thyroid gland [nTPM]":"56.1","Tissue RNA - tongue [nTPM]":"337.6","Tissue RNA - tonsil [nTPM]":"30.4","Tissue RNA - urinary bladder [nTPM]":"51.2","Tissue RNA - vagina [nTPM]":"36.2","Tissue RNA - white matter [nTPM]":"40.5","Cell RNA - A-431 [nTPM]":"93.6","Cell RNA - A549 [nTPM]":"54.0","Cell RNA - AF22 [nTPM]":"52.6","Cell RNA - AN3-CA [nTPM]":"72.7","Cell RNA - ASC diff [nTPM]":"59.7","Cell RNA - ASC TERT1 [nTPM]":"47.2","Cell RNA - BEWO [nTPM]":"58.8","Cell RNA - BJ [nTPM]":"76.0","Cell RNA - BJ hTERT+ [nTPM]":"66.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"96.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"72.6","Cell RNA - CACO-2 [nTPM]":"88.7","Cell RNA - CAPAN-2 [nTPM]":"51.8","Cell RNA - Daudi [nTPM]":"68.8","Cell RNA - EFO-21 [nTPM]":"74.8","Cell RNA - fHDF\/TERT166 [nTPM]":"92.6","Cell RNA - GAMG [nTPM]":"60.6","Cell RNA - HaCaT [nTPM]":"80.5","Cell RNA - HAP1 [nTPM]":"101.7","Cell RNA - HBEC3-KT [nTPM]":"156.1","Cell RNA - HBF TERT88 [nTPM]":"90.6","Cell RNA - HDLM-2 [nTPM]":"60.6","Cell RNA - HEK 293 [nTPM]":"75.4","Cell RNA - HEL [nTPM]":"94.5","Cell RNA - HeLa [nTPM]":"81.8","Cell RNA - Hep G2 [nTPM]":"54.2","Cell RNA - HHSteC [nTPM]":"53.8","Cell RNA - HL-60 [nTPM]":"114.2","Cell RNA - HMC-1 [nTPM]":"51.9","Cell RNA - HSkMC [nTPM]":"57.0","Cell RNA - hTCEpi [nTPM]":"105.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"133.1","Cell RNA - hTERT-HME1 [nTPM]":"124.5","Cell RNA - hTERT-RPE1 [nTPM]":"40.1","Cell RNA - HUVEC TERT2 [nTPM]":"66.2","Cell RNA - JURKAT [nTPM]":"26.4","Cell RNA - K-562 [nTPM]":"106.1","Cell RNA - Karpas-707 [nTPM]":"53.6","Cell RNA - LHCN-M2 [nTPM]":"69.7","Cell RNA - MCF7 [nTPM]":"30.2","Cell RNA - MOLT-4 [nTPM]":"60.2","Cell RNA - NB-4 [nTPM]":"15.2","Cell RNA - NTERA-2 [nTPM]":"39.7","Cell RNA - OE19 [nTPM]":"57.8","Cell RNA - PC-3 [nTPM]":"77.4","Cell RNA - REH [nTPM]":"68.2","Cell RNA - RH-30 [nTPM]":"95.8","Cell RNA - RPMI-8226 [nTPM]":"58.5","Cell RNA - RPTEC TERT1 [nTPM]":"44.9","Cell RNA - RT4 [nTPM]":"61.4","Cell RNA - SCLC-21H [nTPM]":"68.2","Cell RNA - SH-SY5Y [nTPM]":"44.6","Cell RNA - SiHa [nTPM]":"88.4","Cell RNA - SK-BR-3 [nTPM]":"81.0","Cell RNA - SK-MEL-30 [nTPM]":"74.6","Cell RNA - SuSa [nTPM]":"41.4","Cell RNA - T-47d [nTPM]":"43.8","Cell RNA - THP-1 [nTPM]":"49.2","Cell RNA - TIME [nTPM]":"71.2","Cell RNA - U-138 MG [nTPM]":"63.1","Cell RNA - U-2 OS [nTPM]":"58.3","Cell RNA - U-2197 [nTPM]":"88.4","Cell RNA - U-251 MG [nTPM]":"71.2","Cell RNA - U-266\/70 [nTPM]":"59.0","Cell RNA - U-266\/84 [nTPM]":"86.4","Cell RNA - U-698 [nTPM]":"120.7","Cell RNA - U-87 MG [nTPM]":"69.0","Cell RNA - U-937 [nTPM]":"99.6","Cell RNA - WM-115 [nTPM]":"69.8","Blood RNA - basophil [nTPM]":"10.4","Blood RNA - classical monocyte [nTPM]":"11.5","Blood RNA - eosinophil [nTPM]":"7.6","Blood RNA - gdT-cell [nTPM]":"8.9","Blood RNA - intermediate monocyte [nTPM]":"14.0","Blood RNA - MAIT T-cell [nTPM]":"10.2","Blood RNA - memory B-cell [nTPM]":"6.7","Blood RNA - memory CD4 T-cell [nTPM]":"6.7","Blood RNA - memory CD8 T-cell [nTPM]":"7.9","Blood RNA - myeloid DC [nTPM]":"9.7","Blood RNA - naive B-cell [nTPM]":"4.8","Blood RNA - naive CD4 T-cell [nTPM]":"5.0","Blood RNA - naive CD8 T-cell [nTPM]":"6.2","Blood RNA - neutrophil [nTPM]":"16.2","Blood RNA - NK-cell [nTPM]":"6.2","Blood RNA - non-classical monocyte [nTPM]":"18.3","Blood RNA - plasmacytoid DC [nTPM]":"4.2","Blood RNA - T-reg [nTPM]":"8.1","Blood RNA - total PBMC [nTPM]":"15.7","Brain RNA - amygdala [nTPM]":"39.9","Brain RNA - basal ganglia [nTPM]":"42.4","Brain RNA - cerebellum [nTPM]":"39.1","Brain RNA - cerebral cortex [nTPM]":"41.4","Brain RNA - hippocampal formation [nTPM]":"34.7","Brain RNA - hypothalamus [nTPM]":"43.0","Brain RNA - medulla oblongata [nTPM]":"41.1","Brain RNA - midbrain [nTPM]":"44.8","Brain RNA - pons [nTPM]":"40.6","Brain RNA - spinal cord [nTPM]":"43.5","Brain RNA - thalamus [nTPM]":"48.8","Brain RNA - white matter [nTPM]":"40.5","Single Cell Type RNA - Adipocytes [nTPM]":"18.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.8","Single Cell Type RNA - Astrocytes [nTPM]":"16.6","Single Cell Type RNA - B-cells [nTPM]":"10.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"22.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.9","Single Cell Type RNA - Bipolar cells [nTPM]":"26.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"336.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"14.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.1","Single Cell Type RNA - dendritic cells [nTPM]":"12.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"39.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"13.6","Single Cell Type RNA - Early spermatids [nTPM]":"4.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.1","Single Cell Type RNA - Endothelial cells [nTPM]":"18.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.0","Single Cell Type RNA - Erythroid cells [nTPM]":"32.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"21.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"20.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.5","Single Cell Type RNA - Fibroblasts [nTPM]":"17.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.8","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"12.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"46.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.0","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"22.2","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"23.9","Single Cell Type RNA - Langerhans cells [nTPM]":"9.7","Single Cell Type RNA - Late spermatids [nTPM]":"8.0","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"19.1","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"17.3","Single Cell Type RNA - Muller glia cells [nTPM]":"14.6","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.5","Single Cell Type RNA - Paneth cells [nTPM]":"16.8","Single Cell Type RNA - Peritubular cells [nTPM]":"15.1","Single Cell Type RNA - Plasma cells [nTPM]":"10.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"41.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.5","Single Cell Type RNA - Spermatocytes [nTPM]":"25.9","Single Cell Type RNA - Spermatogonia [nTPM]":"15.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"30.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"25.2","Single Cell Type RNA - T-cells [nTPM]":"10.3","Single Cell Type RNA - Theca cells [nTPM]":"12.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.4","Single Cell Type RNA - Urothelial cells [nTPM]":"16.6"},{"Gene":"MFSD2A","Gene synonym":["FLJ14490","MFSD2"],"Ensembl":"ENSG00000168389","Gene description":"Major facilitator superfamily domain containing 2A","Uniprot":["Q8NA29"],"Chromosome":"1","Position":"39955112-39969968","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Primary microcephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"96.9","liver":"162.0","skin 1":"87.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"136.2","Hepatocytes":"299.6","Proximal enterocytes":"235.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"classical monocyte":"13.2","intermediate monocyte":"6.6","myeloid DC":"14.7","plasmacytoid DC":"24.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"dendritic cells":"24.3","monocytes":"13.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTEC\/SVTERT24-B":"52.0","THP-1":"169.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043107"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol","Cytoplasmic bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane","Cytoplasmic bodies"],"Antibody RRID":{"HPA043107":"AB_10794387"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.22e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.33e-4"},"Tissue RNA - adipose tissue [nTPM]":"6.3","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"34.0","Tissue RNA - appendix [nTPM]":"3.4","Tissue RNA - basal ganglia [nTPM]":"31.7","Tissue RNA - bone marrow [nTPM]":"8.4","Tissue RNA - breast [nTPM]":"13.4","Tissue RNA - cerebellum [nTPM]":"34.8","Tissue RNA - cerebral cortex [nTPM]":"36.0","Tissue RNA - cervix [nTPM]":"4.8","Tissue RNA - choroid plexus [nTPM]":"22.2","Tissue RNA - colon [nTPM]":"7.2","Tissue RNA - duodenum [nTPM]":"14.6","Tissue RNA - endometrium 1 [nTPM]":"8.5","Tissue RNA - epididymis [nTPM]":"96.9","Tissue RNA - esophagus [nTPM]":"12.5","Tissue RNA - fallopian tube [nTPM]":"3.5","Tissue RNA - gallbladder [nTPM]":"2.3","Tissue RNA - heart muscle [nTPM]":"1.4","Tissue RNA - hippocampal formation [nTPM]":"30.9","Tissue RNA - hypothalamus [nTPM]":"33.4","Tissue RNA - kidney [nTPM]":"5.8","Tissue RNA - liver [nTPM]":"162.0","Tissue RNA - lung [nTPM]":"36.1","Tissue RNA - lymph node [nTPM]":"2.3","Tissue RNA - medulla oblongata [nTPM]":"38.5","Tissue RNA - midbrain [nTPM]":"33.8","Tissue RNA - ovary [nTPM]":"2.2","Tissue RNA - pancreas [nTPM]":"0.6","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"8.0","Tissue RNA - placenta [nTPM]":"17.1","Tissue RNA - pons [nTPM]":"38.6","Tissue RNA - prostate [nTPM]":"2.4","Tissue RNA - rectum [nTPM]":"5.0","Tissue RNA - retina [nTPM]":"2.6","Tissue RNA - salivary gland [nTPM]":"4.0","Tissue RNA - seminal vesicle [nTPM]":"79.2","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"87.8","Tissue RNA - small intestine [nTPM]":"32.0","Tissue RNA - smooth muscle [nTPM]":"3.5","Tissue RNA - spinal cord [nTPM]":"32.8","Tissue RNA - spleen [nTPM]":"1.5","Tissue RNA - stomach 1 [nTPM]":"1.9","Tissue RNA - testis [nTPM]":"33.9","Tissue RNA - thalamus [nTPM]":"37.2","Tissue RNA - thymus [nTPM]":"1.6","Tissue RNA - thyroid gland [nTPM]":"7.5","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"3.6","Tissue RNA - urinary bladder [nTPM]":"20.2","Tissue RNA - vagina [nTPM]":"14.1","Tissue RNA - white matter [nTPM]":"33.1","Cell RNA - A-431 [nTPM]":"6.2","Cell RNA - A549 [nTPM]":"2.7","Cell RNA - AF22 [nTPM]":"12.5","Cell RNA - AN3-CA [nTPM]":"18.9","Cell RNA - ASC diff [nTPM]":"8.7","Cell RNA - ASC TERT1 [nTPM]":"1.6","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"5.9","Cell RNA - BJ hTERT+ [nTPM]":"11.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.1","Cell RNA - CACO-2 [nTPM]":"0.8","Cell RNA - CAPAN-2 [nTPM]":"3.4","Cell RNA - Daudi [nTPM]":"38.0","Cell RNA - EFO-21 [nTPM]":"3.4","Cell RNA - fHDF\/TERT166 [nTPM]":"3.0","Cell RNA - GAMG [nTPM]":"8.8","Cell RNA - HaCaT [nTPM]":"15.0","Cell RNA - HAP1 [nTPM]":"12.4","Cell RNA - HBEC3-KT [nTPM]":"21.8","Cell RNA - HBF TERT88 [nTPM]":"9.8","Cell RNA - HDLM-2 [nTPM]":"4.9","Cell RNA - HEK 293 [nTPM]":"6.0","Cell RNA - HEL [nTPM]":"4.6","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"28.8","Cell RNA - HL-60 [nTPM]":"6.8","Cell RNA - HMC-1 [nTPM]":"21.8","Cell RNA - HSkMC [nTPM]":"9.7","Cell RNA - hTCEpi [nTPM]":"13.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"52.0","Cell RNA - hTERT-HME1 [nTPM]":"21.5","Cell RNA - hTERT-RPE1 [nTPM]":"2.3","Cell RNA - HUVEC TERT2 [nTPM]":"3.1","Cell RNA - JURKAT [nTPM]":"11.5","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"9.5","Cell RNA - LHCN-M2 [nTPM]":"5.7","Cell RNA - MCF7 [nTPM]":"0.8","Cell RNA - MOLT-4 [nTPM]":"10.6","Cell RNA - NB-4 [nTPM]":"10.4","Cell RNA - NTERA-2 [nTPM]":"10.1","Cell RNA - OE19 [nTPM]":"21.4","Cell RNA - PC-3 [nTPM]":"4.7","Cell RNA - REH [nTPM]":"7.4","Cell RNA - RH-30 [nTPM]":"18.5","Cell RNA - RPMI-8226 [nTPM]":"8.7","Cell RNA - RPTEC TERT1 [nTPM]":"2.1","Cell RNA - RT4 [nTPM]":"17.9","Cell RNA - SCLC-21H [nTPM]":"4.4","Cell RNA - SH-SY5Y [nTPM]":"6.7","Cell RNA - SiHa [nTPM]":"4.5","Cell RNA - SK-BR-3 [nTPM]":"31.7","Cell RNA - SK-MEL-30 [nTPM]":"3.0","Cell RNA - SuSa [nTPM]":"1.1","Cell RNA - T-47d [nTPM]":"1.5","Cell RNA - THP-1 [nTPM]":"169.8","Cell RNA - TIME [nTPM]":"2.0","Cell RNA - U-138 MG [nTPM]":"2.7","Cell RNA - U-2 OS [nTPM]":"5.3","Cell RNA - U-2197 [nTPM]":"9.5","Cell RNA - U-251 MG [nTPM]":"24.9","Cell RNA - U-266\/70 [nTPM]":"1.8","Cell RNA - U-266\/84 [nTPM]":"3.5","Cell RNA - U-698 [nTPM]":"8.5","Cell RNA - U-87 MG [nTPM]":"28.9","Cell RNA - U-937 [nTPM]":"26.0","Cell RNA - WM-115 [nTPM]":"9.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"13.2","Blood RNA - eosinophil [nTPM]":"1.4","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"6.6","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"14.7","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"1.2","Blood RNA - plasmacytoid DC [nTPM]":"24.3","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"3.6","Brain RNA - amygdala [nTPM]":"34.0","Brain RNA - basal ganglia [nTPM]":"31.7","Brain RNA - cerebellum [nTPM]":"34.8","Brain RNA - cerebral cortex [nTPM]":"36.0","Brain RNA - hippocampal formation [nTPM]":"30.9","Brain RNA - hypothalamus [nTPM]":"33.4","Brain RNA - medulla oblongata [nTPM]":"38.5","Brain RNA - midbrain [nTPM]":"33.8","Brain RNA - pons [nTPM]":"38.6","Brain RNA - spinal cord [nTPM]":"32.8","Brain RNA - thalamus [nTPM]":"37.2","Brain RNA - white matter [nTPM]":"33.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"136.2","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"6.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"52.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"40.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"51.2","Single Cell Type RNA - Bipolar cells [nTPM]":"2.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"30.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"5.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"62.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.4","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.5","Single Cell Type RNA - Endothelial cells [nTPM]":"22.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"5.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"24.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.6","Single Cell Type RNA - Fibroblasts [nTPM]":"9.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"24.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"61.8","Single Cell Type RNA - granulocytes [nTPM]":"17.2","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.1","Single Cell Type RNA - Hepatocytes [nTPM]":"299.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"34.5","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"9.8","Single Cell Type RNA - Langerhans cells [nTPM]":"43.3","Single Cell Type RNA - Late spermatids [nTPM]":"2.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"16.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"38.4","Single Cell Type RNA - monocytes [nTPM]":"5.5","Single Cell Type RNA - Muller glia cells [nTPM]":"38.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"27.2","Single Cell Type RNA - Paneth cells [nTPM]":"39.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"5.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"235.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"49.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"54.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"52.5","Single Cell Type RNA - T-cells [nTPM]":"3.3","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.7","Single Cell Type RNA - Urothelial cells [nTPM]":"26.6"},{"Gene":"MFSD8","Gene synonym":["CLN7","MGC33302"],"Ensembl":"ENSG00000164073","Gene description":"Major facilitator superfamily domain containing 8","Uniprot":["Q8NHS3"],"Chromosome":"4","Position":"127917799-127966034","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration","Neuronal ceroid lipofuscinosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044802"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA044802":"AB_10963221"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.21e-4"},"Tissue RNA - adipose tissue [nTPM]":"4.6","Tissue RNA - adrenal gland [nTPM]":"5.7","Tissue RNA - amygdala [nTPM]":"1.3","Tissue RNA - appendix [nTPM]":"6.8","Tissue RNA - basal ganglia [nTPM]":"1.3","Tissue RNA - bone marrow [nTPM]":"2.6","Tissue RNA - breast [nTPM]":"6.9","Tissue RNA - cerebellum [nTPM]":"1.9","Tissue RNA - cerebral cortex [nTPM]":"1.6","Tissue RNA - cervix [nTPM]":"6.2","Tissue RNA - choroid plexus [nTPM]":"1.1","Tissue RNA - colon [nTPM]":"6.8","Tissue RNA - duodenum [nTPM]":"10.0","Tissue RNA - endometrium 1 [nTPM]":"5.6","Tissue RNA - epididymis [nTPM]":"3.9","Tissue RNA - esophagus [nTPM]":"5.4","Tissue RNA - fallopian tube [nTPM]":"5.5","Tissue RNA - gallbladder [nTPM]":"4.8","Tissue RNA - heart muscle [nTPM]":"3.8","Tissue RNA - hippocampal formation [nTPM]":"1.1","Tissue RNA - hypothalamus [nTPM]":"1.7","Tissue RNA - kidney [nTPM]":"6.4","Tissue RNA - liver [nTPM]":"10.0","Tissue RNA - lung [nTPM]":"4.8","Tissue RNA - lymph node [nTPM]":"5.4","Tissue RNA - medulla oblongata [nTPM]":"1.4","Tissue RNA - midbrain [nTPM]":"1.3","Tissue RNA - ovary [nTPM]":"6.8","Tissue RNA - pancreas [nTPM]":"8.1","Tissue RNA - parathyroid gland [nTPM]":"9.1","Tissue RNA - pituitary gland [nTPM]":"7.1","Tissue RNA - placenta [nTPM]":"5.9","Tissue RNA - pons [nTPM]":"1.5","Tissue RNA - prostate [nTPM]":"5.5","Tissue RNA - rectum [nTPM]":"8.2","Tissue RNA - retina [nTPM]":"4.6","Tissue RNA - salivary gland [nTPM]":"5.8","Tissue RNA - seminal vesicle [nTPM]":"4.4","Tissue RNA - skeletal muscle [nTPM]":"3.7","Tissue RNA - skin 1 [nTPM]":"5.9","Tissue RNA - small intestine [nTPM]":"7.6","Tissue RNA - smooth muscle [nTPM]":"5.8","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"7.3","Tissue RNA - stomach 1 [nTPM]":"6.4","Tissue RNA - testis [nTPM]":"3.9","Tissue RNA - thalamus [nTPM]":"0.8","Tissue RNA - thymus [nTPM]":"5.2","Tissue RNA - thyroid gland [nTPM]":"7.0","Tissue RNA - tongue [nTPM]":"4.4","Tissue RNA - tonsil [nTPM]":"7.9","Tissue RNA - urinary bladder [nTPM]":"5.3","Tissue RNA - vagina [nTPM]":"5.9","Tissue RNA - white matter [nTPM]":"2.2","Cell RNA - A-431 [nTPM]":"10.9","Cell RNA - A549 [nTPM]":"7.3","Cell RNA - AF22 [nTPM]":"9.5","Cell RNA - AN3-CA [nTPM]":"4.6","Cell RNA - ASC diff [nTPM]":"7.2","Cell RNA - ASC TERT1 [nTPM]":"6.9","Cell RNA - BEWO [nTPM]":"7.0","Cell RNA - BJ [nTPM]":"8.3","Cell RNA - BJ hTERT+ [nTPM]":"10.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.5","Cell RNA - CACO-2 [nTPM]":"5.2","Cell RNA - CAPAN-2 [nTPM]":"14.3","Cell RNA - Daudi [nTPM]":"5.2","Cell RNA - EFO-21 [nTPM]":"14.5","Cell RNA - fHDF\/TERT166 [nTPM]":"14.3","Cell RNA - GAMG [nTPM]":"14.8","Cell RNA - HaCaT [nTPM]":"7.8","Cell RNA - HAP1 [nTPM]":"10.2","Cell RNA - HBEC3-KT [nTPM]":"7.4","Cell RNA - HBF TERT88 [nTPM]":"14.4","Cell RNA - HDLM-2 [nTPM]":"10.8","Cell RNA - HEK 293 [nTPM]":"7.9","Cell RNA - HEL [nTPM]":"5.7","Cell RNA - HeLa [nTPM]":"9.1","Cell RNA - Hep G2 [nTPM]":"8.0","Cell RNA - HHSteC [nTPM]":"9.4","Cell RNA - HL-60 [nTPM]":"6.0","Cell RNA - HMC-1 [nTPM]":"6.6","Cell RNA - HSkMC [nTPM]":"8.3","Cell RNA - hTCEpi [nTPM]":"2.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.6","Cell RNA - hTERT-HME1 [nTPM]":"7.7","Cell RNA - hTERT-RPE1 [nTPM]":"5.0","Cell RNA - HUVEC TERT2 [nTPM]":"10.6","Cell RNA - JURKAT [nTPM]":"6.6","Cell RNA - K-562 [nTPM]":"9.5","Cell RNA - Karpas-707 [nTPM]":"5.9","Cell RNA - LHCN-M2 [nTPM]":"14.6","Cell RNA - MCF7 [nTPM]":"8.9","Cell RNA - MOLT-4 [nTPM]":"5.0","Cell RNA - NB-4 [nTPM]":"1.9","Cell RNA - NTERA-2 [nTPM]":"1.7","Cell RNA - OE19 [nTPM]":"11.8","Cell RNA - PC-3 [nTPM]":"5.2","Cell RNA - REH [nTPM]":"5.3","Cell RNA - RH-30 [nTPM]":"0.6","Cell RNA - RPMI-8226 [nTPM]":"4.7","Cell RNA - RPTEC TERT1 [nTPM]":"7.5","Cell RNA - RT4 [nTPM]":"13.9","Cell RNA - SCLC-21H [nTPM]":"8.5","Cell RNA - SH-SY5Y [nTPM]":"2.9","Cell RNA - SiHa [nTPM]":"9.0","Cell RNA - SK-BR-3 [nTPM]":"12.0","Cell RNA - SK-MEL-30 [nTPM]":"3.5","Cell RNA - SuSa [nTPM]":"6.4","Cell RNA - T-47d [nTPM]":"5.6","Cell RNA - THP-1 [nTPM]":"5.1","Cell RNA - TIME [nTPM]":"6.7","Cell RNA - U-138 MG [nTPM]":"2.9","Cell RNA - U-2 OS [nTPM]":"3.1","Cell RNA - U-2197 [nTPM]":"10.7","Cell RNA - U-251 MG [nTPM]":"7.8","Cell RNA - U-266\/70 [nTPM]":"12.5","Cell RNA - U-266\/84 [nTPM]":"22.1","Cell RNA - U-698 [nTPM]":"9.6","Cell RNA - U-87 MG [nTPM]":"10.3","Cell RNA - U-937 [nTPM]":"5.3","Cell RNA - WM-115 [nTPM]":"8.8","Blood RNA - basophil [nTPM]":"1.9","Blood RNA - classical monocyte [nTPM]":"1.6","Blood RNA - eosinophil [nTPM]":"2.8","Blood RNA - gdT-cell [nTPM]":"2.5","Blood RNA - intermediate monocyte [nTPM]":"2.4","Blood RNA - MAIT T-cell [nTPM]":"2.4","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"2.7","Blood RNA - memory CD8 T-cell [nTPM]":"2.2","Blood RNA - myeloid DC [nTPM]":"1.6","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"2.4","Blood RNA - naive CD8 T-cell [nTPM]":"2.6","Blood RNA - neutrophil [nTPM]":"2.5","Blood RNA - NK-cell [nTPM]":"2.4","Blood RNA - non-classical monocyte [nTPM]":"3.7","Blood RNA - plasmacytoid DC [nTPM]":"2.2","Blood RNA - T-reg [nTPM]":"3.4","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"1.3","Brain RNA - basal ganglia [nTPM]":"1.3","Brain RNA - cerebellum [nTPM]":"1.9","Brain RNA - cerebral cortex [nTPM]":"1.6","Brain RNA - hippocampal formation [nTPM]":"1.1","Brain RNA - hypothalamus [nTPM]":"1.7","Brain RNA - medulla oblongata [nTPM]":"1.4","Brain RNA - midbrain [nTPM]":"1.3","Brain RNA - pons [nTPM]":"1.5","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"0.8","Brain RNA - white matter [nTPM]":"2.2","Single Cell Type RNA - Adipocytes [nTPM]":"9.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.1","Single Cell Type RNA - Astrocytes [nTPM]":"17.0","Single Cell Type RNA - B-cells [nTPM]":"18.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"17.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"14.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.5","Single Cell Type RNA - dendritic cells [nTPM]":"17.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.5","Single Cell Type RNA - Early spermatids [nTPM]":"10.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.2","Single Cell Type RNA - Endothelial cells [nTPM]":"7.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"32.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.3","Single Cell Type RNA - Fibroblasts [nTPM]":"8.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.2","Single Cell Type RNA - granulocytes [nTPM]":"12.7","Single Cell Type RNA - Granulosa cells [nTPM]":"18.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.9","Single Cell Type RNA - Hepatocytes [nTPM]":"10.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.6","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"34.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.8","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"8.5","Single Cell Type RNA - Langerhans cells [nTPM]":"3.3","Single Cell Type RNA - Late spermatids [nTPM]":"14.7","Single Cell Type RNA - Leydig cells [nTPM]":"9.3","Single Cell Type RNA - Macrophages [nTPM]":"6.5","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"27.2","Single Cell Type RNA - monocytes [nTPM]":"10.5","Single Cell Type RNA - Muller glia cells [nTPM]":"8.6","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"24.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.8","Single Cell Type RNA - Paneth cells [nTPM]":"9.5","Single Cell Type RNA - Peritubular cells [nTPM]":"9.4","Single Cell Type RNA - Plasma cells [nTPM]":"19.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.6","Single Cell Type RNA - Spermatocytes [nTPM]":"12.6","Single Cell Type RNA - Spermatogonia [nTPM]":"8.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.0","Single Cell Type RNA - T-cells [nTPM]":"13.7","Single Cell Type RNA - Theca cells [nTPM]":"11.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.3","Single Cell Type RNA - Urothelial cells [nTPM]":"4.8"},{"Gene":"MGAT2","Gene synonym":["GNT-II"],"Ensembl":"ENSG00000168282","Gene description":"Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase","Uniprot":["Q10469"],"Chromosome":"14","Position":"49620799-49623481","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043721","HPA056824"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5100000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 14: B-cells - Humoral immune response","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA043721":"AB_2678636","HPA056824":"AB_2683248"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.22e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Tissue RNA - adipose tissue [nTPM]":"16.8","Tissue RNA - adrenal gland [nTPM]":"17.6","Tissue RNA - amygdala [nTPM]":"5.9","Tissue RNA - appendix [nTPM]":"24.3","Tissue RNA - basal ganglia [nTPM]":"5.8","Tissue RNA - bone marrow [nTPM]":"10.3","Tissue RNA - breast [nTPM]":"13.3","Tissue RNA - cerebellum [nTPM]":"6.9","Tissue RNA - cerebral cortex [nTPM]":"6.8","Tissue RNA - cervix [nTPM]":"17.4","Tissue RNA - choroid plexus [nTPM]":"9.0","Tissue RNA - colon [nTPM]":"23.6","Tissue RNA - duodenum [nTPM]":"23.1","Tissue RNA - endometrium 1 [nTPM]":"12.7","Tissue RNA - epididymis [nTPM]":"21.7","Tissue RNA - esophagus [nTPM]":"11.8","Tissue RNA - fallopian tube [nTPM]":"11.9","Tissue RNA - gallbladder [nTPM]":"15.2","Tissue RNA - heart muscle [nTPM]":"11.7","Tissue RNA - hippocampal formation [nTPM]":"5.6","Tissue RNA - hypothalamus [nTPM]":"6.7","Tissue RNA - kidney [nTPM]":"14.2","Tissue RNA - liver [nTPM]":"40.7","Tissue RNA - lung [nTPM]":"13.8","Tissue RNA - lymph node [nTPM]":"25.3","Tissue RNA - medulla oblongata [nTPM]":"6.4","Tissue RNA - midbrain [nTPM]":"6.3","Tissue RNA - ovary [nTPM]":"13.1","Tissue RNA - pancreas [nTPM]":"23.8","Tissue RNA - parathyroid gland [nTPM]":"8.2","Tissue RNA - pituitary gland [nTPM]":"7.9","Tissue RNA - placenta [nTPM]":"22.0","Tissue RNA - pons [nTPM]":"6.6","Tissue RNA - prostate [nTPM]":"14.1","Tissue RNA - rectum [nTPM]":"21.9","Tissue RNA - retina [nTPM]":"8.2","Tissue RNA - salivary gland [nTPM]":"15.8","Tissue RNA - seminal vesicle [nTPM]":"13.7","Tissue RNA - skeletal muscle [nTPM]":"5.0","Tissue RNA - skin 1 [nTPM]":"9.3","Tissue RNA - small intestine [nTPM]":"22.5","Tissue RNA - smooth muscle [nTPM]":"16.0","Tissue RNA - spinal cord [nTPM]":"6.9","Tissue RNA - spleen [nTPM]":"20.2","Tissue RNA - stomach 1 [nTPM]":"21.0","Tissue RNA - testis [nTPM]":"24.3","Tissue RNA - thalamus [nTPM]":"7.2","Tissue RNA - thymus [nTPM]":"16.4","Tissue RNA - thyroid gland [nTPM]":"13.3","Tissue RNA - tongue [nTPM]":"5.6","Tissue RNA - tonsil [nTPM]":"25.1","Tissue RNA - urinary bladder [nTPM]":"20.9","Tissue RNA - vagina [nTPM]":"8.8","Tissue RNA - white matter [nTPM]":"7.3","Cell RNA - A-431 [nTPM]":"63.5","Cell RNA - A549 [nTPM]":"30.7","Cell RNA - AF22 [nTPM]":"23.2","Cell RNA - AN3-CA [nTPM]":"39.2","Cell RNA - ASC diff [nTPM]":"53.6","Cell RNA - ASC TERT1 [nTPM]":"51.7","Cell RNA - BEWO [nTPM]":"15.1","Cell RNA - BJ [nTPM]":"68.6","Cell RNA - BJ hTERT+ [nTPM]":"67.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"62.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"55.8","Cell RNA - CACO-2 [nTPM]":"37.5","Cell RNA - CAPAN-2 [nTPM]":"47.1","Cell RNA - Daudi [nTPM]":"63.7","Cell RNA - EFO-21 [nTPM]":"56.9","Cell RNA - fHDF\/TERT166 [nTPM]":"62.9","Cell RNA - GAMG [nTPM]":"36.0","Cell RNA - HaCaT [nTPM]":"49.5","Cell RNA - HAP1 [nTPM]":"32.9","Cell RNA - HBEC3-KT [nTPM]":"39.7","Cell RNA - HBF TERT88 [nTPM]":"66.7","Cell RNA - HDLM-2 [nTPM]":"65.5","Cell RNA - HEK 293 [nTPM]":"29.1","Cell RNA - HEL [nTPM]":"40.7","Cell RNA - HeLa [nTPM]":"21.7","Cell RNA - Hep G2 [nTPM]":"37.2","Cell RNA - HHSteC [nTPM]":"42.3","Cell RNA - HL-60 [nTPM]":"94.5","Cell RNA - HMC-1 [nTPM]":"91.2","Cell RNA - HSkMC [nTPM]":"39.8","Cell RNA - hTCEpi [nTPM]":"31.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"36.8","Cell RNA - hTERT-HME1 [nTPM]":"51.8","Cell RNA - hTERT-RPE1 [nTPM]":"45.5","Cell RNA - HUVEC TERT2 [nTPM]":"75.5","Cell RNA - JURKAT [nTPM]":"31.4","Cell RNA - K-562 [nTPM]":"31.7","Cell RNA - Karpas-707 [nTPM]":"170.4","Cell RNA - LHCN-M2 [nTPM]":"66.3","Cell RNA - MCF7 [nTPM]":"24.2","Cell RNA - MOLT-4 [nTPM]":"32.9","Cell RNA - NB-4 [nTPM]":"60.1","Cell RNA - NTERA-2 [nTPM]":"23.8","Cell RNA - OE19 [nTPM]":"22.2","Cell RNA - PC-3 [nTPM]":"49.1","Cell RNA - REH [nTPM]":"36.7","Cell RNA - RH-30 [nTPM]":"67.1","Cell RNA - RPMI-8226 [nTPM]":"55.6","Cell RNA - RPTEC TERT1 [nTPM]":"49.3","Cell RNA - RT4 [nTPM]":"36.2","Cell RNA - SCLC-21H [nTPM]":"24.0","Cell RNA - SH-SY5Y [nTPM]":"25.6","Cell RNA - SiHa [nTPM]":"49.3","Cell RNA - SK-BR-3 [nTPM]":"12.9","Cell RNA - SK-MEL-30 [nTPM]":"39.8","Cell RNA - SuSa [nTPM]":"22.2","Cell RNA - T-47d [nTPM]":"39.1","Cell RNA - THP-1 [nTPM]":"63.6","Cell RNA - TIME [nTPM]":"78.9","Cell RNA - U-138 MG [nTPM]":"56.1","Cell RNA - U-2 OS [nTPM]":"60.8","Cell RNA - U-2197 [nTPM]":"41.1","Cell RNA - U-251 MG [nTPM]":"49.6","Cell RNA - U-266\/70 [nTPM]":"182.8","Cell RNA - U-266\/84 [nTPM]":"94.6","Cell RNA - U-698 [nTPM]":"56.7","Cell RNA - U-87 MG [nTPM]":"27.3","Cell RNA - U-937 [nTPM]":"46.5","Cell RNA - WM-115 [nTPM]":"38.6","Blood RNA - basophil [nTPM]":"49.4","Blood RNA - classical monocyte [nTPM]":"38.6","Blood RNA - eosinophil [nTPM]":"39.3","Blood RNA - gdT-cell [nTPM]":"36.6","Blood RNA - intermediate monocyte [nTPM]":"34.1","Blood RNA - MAIT T-cell [nTPM]":"39.3","Blood RNA - memory B-cell [nTPM]":"25.1","Blood RNA - memory CD4 T-cell [nTPM]":"33.3","Blood RNA - memory CD8 T-cell [nTPM]":"33.1","Blood RNA - myeloid DC [nTPM]":"39.9","Blood RNA - naive B-cell [nTPM]":"15.9","Blood RNA - naive CD4 T-cell [nTPM]":"19.3","Blood RNA - naive CD8 T-cell [nTPM]":"26.8","Blood RNA - neutrophil [nTPM]":"11.6","Blood RNA - NK-cell [nTPM]":"22.3","Blood RNA - non-classical monocyte [nTPM]":"39.8","Blood RNA - plasmacytoid DC [nTPM]":"47.2","Blood RNA - T-reg [nTPM]":"31.6","Blood RNA - total PBMC [nTPM]":"44.8","Brain RNA - amygdala [nTPM]":"5.9","Brain RNA - basal ganglia [nTPM]":"5.8","Brain RNA - cerebellum [nTPM]":"6.9","Brain RNA - cerebral cortex [nTPM]":"6.8","Brain RNA - hippocampal formation [nTPM]":"5.6","Brain RNA - hypothalamus [nTPM]":"6.7","Brain RNA - medulla oblongata [nTPM]":"6.4","Brain RNA - midbrain [nTPM]":"6.3","Brain RNA - pons [nTPM]":"6.6","Brain RNA - spinal cord [nTPM]":"6.9","Brain RNA - thalamus [nTPM]":"7.2","Brain RNA - white matter [nTPM]":"7.3","Single Cell Type RNA - Adipocytes [nTPM]":"17.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.6","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"31.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"25.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"28.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"13.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"18.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"26.4","Single Cell Type RNA - dendritic cells [nTPM]":"46.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"34.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"31.0","Single Cell Type RNA - Early spermatids [nTPM]":"7.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.7","Single Cell Type RNA - Endothelial cells [nTPM]":"20.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.1","Single Cell Type RNA - Erythroid cells [nTPM]":"19.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"34.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"40.3","Single Cell Type RNA - Fibroblasts [nTPM]":"24.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.7","Single Cell Type RNA - granulocytes [nTPM]":"17.1","Single Cell Type RNA - Granulosa cells [nTPM]":"27.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"27.1","Single Cell Type RNA - Hepatocytes [nTPM]":"63.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"37.2","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.5","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"34.5","Single Cell Type RNA - Langerhans cells [nTPM]":"28.8","Single Cell Type RNA - Late spermatids [nTPM]":"6.0","Single Cell Type RNA - Leydig cells [nTPM]":"17.4","Single Cell Type RNA - Macrophages [nTPM]":"26.3","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"40.6","Single Cell Type RNA - Muller glia cells [nTPM]":"16.7","Single Cell Type RNA - NK-cells [nTPM]":"63.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"36.5","Single Cell Type RNA - Paneth cells [nTPM]":"25.1","Single Cell Type RNA - Peritubular cells [nTPM]":"22.2","Single Cell Type RNA - Plasma cells [nTPM]":"77.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"27.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"26.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"34.6","Single Cell Type RNA - Spermatocytes [nTPM]":"56.4","Single Cell Type RNA - Spermatogonia [nTPM]":"13.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.3","Single Cell Type RNA - T-cells [nTPM]":"31.5","Single Cell Type RNA - Theca cells [nTPM]":"23.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.0","Single Cell Type RNA - Urothelial cells [nTPM]":"25.5"},{"Gene":"MIA2","Gene synonym":["cTAGE-5A","cTAGE-5B","cTAGE-5C","cTAGE-5D","CTAGE5","FLJ22404","MEA6","MGEA","MGEA11","MGEA6","TALI"],"Ensembl":"ENSG00000150527","Gene description":"MIA SH3 domain ER export factor 2","Uniprot":["Q96PC5"],"Chromosome":"14","Position":"39230231-39388513","Protein class":["Disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"138.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"44.1","Ductal cells":"42.9","Endometrial ciliated cells":"78.7","Exocrine glandular cells":"42.7","Glandular and luminal cells":"93.5","Pancreatic endocrine cells":"41.3","Proximal tubular cells":"61.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"125.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000387","HPA000922","HPA054066","HPA055459"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA000387":"AB_1078582","HPA000922":"AB_1078581","HPA054066":"AB_2682368","HPA055459":"AB_2682819"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.81e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Tissue RNA - adipose tissue [nTPM]":"12.1","Tissue RNA - adrenal gland [nTPM]":"26.6","Tissue RNA - amygdala [nTPM]":"5.6","Tissue RNA - appendix [nTPM]":"16.8","Tissue RNA - basal ganglia [nTPM]":"6.9","Tissue RNA - bone marrow [nTPM]":"23.6","Tissue RNA - breast [nTPM]":"22.1","Tissue RNA - cerebellum [nTPM]":"5.8","Tissue RNA - cerebral cortex [nTPM]":"7.9","Tissue RNA - cervix [nTPM]":"29.7","Tissue RNA - choroid plexus [nTPM]":"58.0","Tissue RNA - colon [nTPM]":"30.8","Tissue RNA - duodenum [nTPM]":"80.4","Tissue RNA - endometrium 1 [nTPM]":"15.7","Tissue RNA - epididymis [nTPM]":"40.2","Tissue RNA - esophagus [nTPM]":"26.9","Tissue RNA - fallopian tube [nTPM]":"22.2","Tissue RNA - gallbladder [nTPM]":"30.3","Tissue RNA - heart muscle [nTPM]":"16.6","Tissue RNA - hippocampal formation [nTPM]":"9.4","Tissue RNA - hypothalamus [nTPM]":"6.5","Tissue RNA - kidney [nTPM]":"78.4","Tissue RNA - liver [nTPM]":"138.9","Tissue RNA - lung [nTPM]":"15.5","Tissue RNA - lymph node [nTPM]":"16.2","Tissue RNA - medulla oblongata [nTPM]":"5.6","Tissue RNA - midbrain [nTPM]":"4.7","Tissue RNA - ovary [nTPM]":"9.6","Tissue RNA - pancreas [nTPM]":"43.6","Tissue RNA - parathyroid gland [nTPM]":"40.5","Tissue RNA - pituitary gland [nTPM]":"15.5","Tissue RNA - placenta [nTPM]":"11.2","Tissue RNA - pons [nTPM]":"6.4","Tissue RNA - prostate [nTPM]":"21.1","Tissue RNA - rectum [nTPM]":"34.6","Tissue RNA - retina [nTPM]":"12.8","Tissue RNA - salivary gland [nTPM]":"52.5","Tissue RNA - seminal vesicle [nTPM]":"19.2","Tissue RNA - skeletal muscle [nTPM]":"54.5","Tissue RNA - skin 1 [nTPM]":"9.9","Tissue RNA - small intestine [nTPM]":"78.4","Tissue RNA - smooth muscle [nTPM]":"12.3","Tissue RNA - spinal cord [nTPM]":"4.1","Tissue RNA - spleen [nTPM]":"14.5","Tissue RNA - stomach 1 [nTPM]":"45.3","Tissue RNA - testis [nTPM]":"21.0","Tissue RNA - thalamus [nTPM]":"5.1","Tissue RNA - thymus [nTPM]":"14.3","Tissue RNA - thyroid gland [nTPM]":"46.7","Tissue RNA - tongue [nTPM]":"20.7","Tissue RNA - tonsil [nTPM]":"19.8","Tissue RNA - urinary bladder [nTPM]":"16.2","Tissue RNA - vagina [nTPM]":"17.2","Tissue RNA - white matter [nTPM]":"7.1","Cell RNA - A-431 [nTPM]":"23.0","Cell RNA - A549 [nTPM]":"25.1","Cell RNA - AF22 [nTPM]":"10.4","Cell RNA - AN3-CA [nTPM]":"18.5","Cell RNA - ASC diff [nTPM]":"20.6","Cell RNA - ASC TERT1 [nTPM]":"23.2","Cell RNA - BEWO [nTPM]":"14.5","Cell RNA - BJ [nTPM]":"13.3","Cell RNA - BJ hTERT+ [nTPM]":"13.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.6","Cell RNA - CACO-2 [nTPM]":"19.7","Cell RNA - CAPAN-2 [nTPM]":"125.4","Cell RNA - Daudi [nTPM]":"27.5","Cell RNA - EFO-21 [nTPM]":"40.1","Cell RNA - fHDF\/TERT166 [nTPM]":"15.0","Cell RNA - GAMG [nTPM]":"18.9","Cell RNA - HaCaT [nTPM]":"34.1","Cell RNA - HAP1 [nTPM]":"12.7","Cell RNA - HBEC3-KT [nTPM]":"15.0","Cell RNA - HBF TERT88 [nTPM]":"11.0","Cell RNA - HDLM-2 [nTPM]":"21.4","Cell RNA - HEK 293 [nTPM]":"10.6","Cell RNA - HEL [nTPM]":"17.2","Cell RNA - HeLa [nTPM]":"11.5","Cell RNA - Hep G2 [nTPM]":"106.1","Cell RNA - HHSteC [nTPM]":"48.2","Cell RNA - HL-60 [nTPM]":"23.2","Cell RNA - HMC-1 [nTPM]":"30.7","Cell RNA - HSkMC [nTPM]":"14.4","Cell RNA - hTCEpi [nTPM]":"83.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.2","Cell RNA - hTERT-HME1 [nTPM]":"69.2","Cell RNA - hTERT-RPE1 [nTPM]":"59.0","Cell RNA - HUVEC TERT2 [nTPM]":"15.3","Cell RNA - JURKAT [nTPM]":"31.8","Cell RNA - K-562 [nTPM]":"16.6","Cell RNA - Karpas-707 [nTPM]":"68.3","Cell RNA - LHCN-M2 [nTPM]":"14.0","Cell RNA - MCF7 [nTPM]":"22.1","Cell RNA - MOLT-4 [nTPM]":"14.9","Cell RNA - NB-4 [nTPM]":"18.9","Cell RNA - NTERA-2 [nTPM]":"12.0","Cell RNA - OE19 [nTPM]":"87.2","Cell RNA - PC-3 [nTPM]":"20.8","Cell RNA - REH [nTPM]":"15.2","Cell RNA - RH-30 [nTPM]":"18.3","Cell RNA - RPMI-8226 [nTPM]":"34.9","Cell RNA - RPTEC TERT1 [nTPM]":"42.7","Cell RNA - RT4 [nTPM]":"24.7","Cell RNA - SCLC-21H [nTPM]":"8.7","Cell RNA - SH-SY5Y [nTPM]":"5.1","Cell RNA - SiHa [nTPM]":"31.0","Cell RNA - SK-BR-3 [nTPM]":"32.5","Cell RNA - SK-MEL-30 [nTPM]":"20.4","Cell RNA - SuSa [nTPM]":"13.1","Cell RNA - T-47d [nTPM]":"31.2","Cell RNA - THP-1 [nTPM]":"24.8","Cell RNA - TIME [nTPM]":"24.3","Cell RNA - U-138 MG [nTPM]":"14.1","Cell RNA - U-2 OS [nTPM]":"9.2","Cell RNA - U-2197 [nTPM]":"10.4","Cell RNA - U-251 MG [nTPM]":"8.8","Cell RNA - U-266\/70 [nTPM]":"38.7","Cell RNA - U-266\/84 [nTPM]":"35.7","Cell RNA - U-698 [nTPM]":"27.2","Cell RNA - U-87 MG [nTPM]":"7.9","Cell RNA - U-937 [nTPM]":"14.5","Cell RNA - WM-115 [nTPM]":"12.0","Blood RNA - basophil [nTPM]":"40.9","Blood RNA - classical monocyte [nTPM]":"16.3","Blood RNA - eosinophil [nTPM]":"25.9","Blood RNA - gdT-cell [nTPM]":"15.4","Blood RNA - intermediate monocyte [nTPM]":"18.0","Blood RNA - MAIT T-cell [nTPM]":"14.0","Blood RNA - memory B-cell [nTPM]":"11.7","Blood RNA - memory CD4 T-cell [nTPM]":"11.6","Blood RNA - memory CD8 T-cell [nTPM]":"14.4","Blood RNA - myeloid DC [nTPM]":"17.8","Blood RNA - naive B-cell [nTPM]":"13.1","Blood RNA - naive CD4 T-cell [nTPM]":"14.2","Blood RNA - naive CD8 T-cell [nTPM]":"13.2","Blood RNA - neutrophil [nTPM]":"34.5","Blood RNA - NK-cell [nTPM]":"14.6","Blood RNA - non-classical monocyte [nTPM]":"21.0","Blood RNA - plasmacytoid DC [nTPM]":"12.3","Blood RNA - T-reg [nTPM]":"11.8","Blood RNA - total PBMC [nTPM]":"11.8","Brain RNA - amygdala [nTPM]":"5.6","Brain RNA - basal ganglia [nTPM]":"6.9","Brain RNA - cerebellum [nTPM]":"5.8","Brain RNA - cerebral cortex [nTPM]":"7.9","Brain RNA - hippocampal formation [nTPM]":"9.4","Brain RNA - hypothalamus [nTPM]":"6.5","Brain RNA - medulla oblongata [nTPM]":"5.6","Brain RNA - midbrain [nTPM]":"4.7","Brain RNA - pons [nTPM]":"6.4","Brain RNA - spinal cord [nTPM]":"4.1","Brain RNA - thalamus [nTPM]":"5.1","Brain RNA - white matter [nTPM]":"7.1","Single Cell Type RNA - Adipocytes [nTPM]":"26.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"11.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"33.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"19.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.6","Single Cell Type RNA - dendritic cells [nTPM]":"35.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"42.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"78.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"30.7","Single Cell Type RNA - Endothelial cells [nTPM]":"7.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"42.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.0","Single Cell Type RNA - Fibroblasts [nTPM]":"4.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"93.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"10.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"3.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"12.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"23.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"41.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"8.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"61.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.0","Single Cell Type RNA - T-cells [nTPM]":"13.6","Single Cell Type RNA - Theca cells [nTPM]":"20.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"MIB1","Gene synonym":["DIP-1","KIAA1323","MIB","ZZANK2","ZZZ6"],"Ensembl":"ENSG00000101752","Gene description":"Mindbomb E3 ubiquitin protein ligase 1","Uniprot":["Q86YT6"],"Chromosome":"18","Position":"21704957-21870953","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Notch signaling pathway","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Cardiomyopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"121.2","Oligodendrocytes":"109.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"REH":"121.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019100","CAB037044"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 14: REH - Unknown function","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB037044":"AB_1841007","HPA019100":"AB_1853934"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.33e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.1","Tissue RNA - adrenal gland [nTPM]":"6.3","Tissue RNA - amygdala [nTPM]":"9.1","Tissue RNA - appendix [nTPM]":"6.0","Tissue RNA - basal ganglia [nTPM]":"9.1","Tissue RNA - bone marrow [nTPM]":"4.9","Tissue RNA - breast [nTPM]":"11.2","Tissue RNA - cerebellum [nTPM]":"9.2","Tissue RNA - cerebral cortex [nTPM]":"8.5","Tissue RNA - cervix [nTPM]":"11.0","Tissue RNA - choroid plexus [nTPM]":"8.0","Tissue RNA - colon [nTPM]":"7.1","Tissue RNA - duodenum [nTPM]":"5.1","Tissue RNA - endometrium 1 [nTPM]":"13.0","Tissue RNA - epididymis [nTPM]":"9.5","Tissue RNA - esophagus [nTPM]":"8.0","Tissue RNA - fallopian tube [nTPM]":"7.1","Tissue RNA - gallbladder [nTPM]":"8.6","Tissue RNA - heart muscle [nTPM]":"6.0","Tissue RNA - hippocampal formation [nTPM]":"8.4","Tissue RNA - hypothalamus [nTPM]":"9.2","Tissue RNA - kidney [nTPM]":"11.1","Tissue RNA - liver [nTPM]":"10.4","Tissue RNA - lung [nTPM]":"7.2","Tissue RNA - lymph node [nTPM]":"7.6","Tissue RNA - medulla oblongata [nTPM]":"9.5","Tissue RNA - midbrain [nTPM]":"10.2","Tissue RNA - ovary [nTPM]":"11.7","Tissue RNA - pancreas [nTPM]":"8.1","Tissue RNA - parathyroid gland [nTPM]":"9.8","Tissue RNA - pituitary gland [nTPM]":"5.2","Tissue RNA - placenta [nTPM]":"11.0","Tissue RNA - pons [nTPM]":"8.6","Tissue RNA - prostate [nTPM]":"10.1","Tissue RNA - rectum [nTPM]":"7.0","Tissue RNA - retina [nTPM]":"8.3","Tissue RNA - salivary gland [nTPM]":"8.4","Tissue RNA - seminal vesicle [nTPM]":"8.5","Tissue RNA - skeletal muscle [nTPM]":"5.8","Tissue RNA - skin 1 [nTPM]":"9.1","Tissue RNA - small intestine [nTPM]":"5.2","Tissue RNA - smooth muscle [nTPM]":"10.2","Tissue RNA - spinal cord [nTPM]":"10.1","Tissue RNA - spleen [nTPM]":"7.2","Tissue RNA - stomach 1 [nTPM]":"7.6","Tissue RNA - testis [nTPM]":"8.7","Tissue RNA - thalamus [nTPM]":"10.3","Tissue RNA - thymus [nTPM]":"11.5","Tissue RNA - thyroid gland [nTPM]":"13.6","Tissue RNA - tongue [nTPM]":"7.0","Tissue RNA - tonsil [nTPM]":"7.9","Tissue RNA - urinary bladder [nTPM]":"8.4","Tissue RNA - vagina [nTPM]":"8.2","Tissue RNA - white matter [nTPM]":"9.6","Cell RNA - A-431 [nTPM]":"19.9","Cell RNA - A549 [nTPM]":"7.6","Cell RNA - AF22 [nTPM]":"36.4","Cell RNA - AN3-CA [nTPM]":"25.8","Cell RNA - ASC diff [nTPM]":"19.5","Cell RNA - ASC TERT1 [nTPM]":"23.0","Cell RNA - BEWO [nTPM]":"9.0","Cell RNA - BJ [nTPM]":"15.6","Cell RNA - BJ hTERT+ [nTPM]":"17.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.6","Cell RNA - CACO-2 [nTPM]":"11.3","Cell RNA - CAPAN-2 [nTPM]":"7.1","Cell RNA - Daudi [nTPM]":"16.9","Cell RNA - EFO-21 [nTPM]":"14.1","Cell RNA - fHDF\/TERT166 [nTPM]":"21.4","Cell RNA - GAMG [nTPM]":"11.8","Cell RNA - HaCaT [nTPM]":"13.2","Cell RNA - HAP1 [nTPM]":"21.4","Cell RNA - HBEC3-KT [nTPM]":"21.0","Cell RNA - HBF TERT88 [nTPM]":"24.4","Cell RNA - HDLM-2 [nTPM]":"22.4","Cell RNA - HEK 293 [nTPM]":"10.4","Cell RNA - HEL [nTPM]":"18.8","Cell RNA - HeLa [nTPM]":"9.7","Cell RNA - Hep G2 [nTPM]":"15.9","Cell RNA - HHSteC [nTPM]":"15.8","Cell RNA - HL-60 [nTPM]":"38.3","Cell RNA - HMC-1 [nTPM]":"7.8","Cell RNA - HSkMC [nTPM]":"14.8","Cell RNA - hTCEpi [nTPM]":"23.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.6","Cell RNA - hTERT-HME1 [nTPM]":"32.0","Cell RNA - hTERT-RPE1 [nTPM]":"16.0","Cell RNA - HUVEC TERT2 [nTPM]":"27.8","Cell RNA - JURKAT [nTPM]":"6.6","Cell RNA - K-562 [nTPM]":"26.5","Cell RNA - Karpas-707 [nTPM]":"47.5","Cell RNA - LHCN-M2 [nTPM]":"17.2","Cell RNA - MCF7 [nTPM]":"9.5","Cell RNA - MOLT-4 [nTPM]":"18.9","Cell RNA - NB-4 [nTPM]":"14.7","Cell RNA - NTERA-2 [nTPM]":"9.5","Cell RNA - OE19 [nTPM]":"12.2","Cell RNA - PC-3 [nTPM]":"10.2","Cell RNA - REH [nTPM]":"121.1","Cell RNA - RH-30 [nTPM]":"30.3","Cell RNA - RPMI-8226 [nTPM]":"42.5","Cell RNA - RPTEC TERT1 [nTPM]":"18.7","Cell RNA - RT4 [nTPM]":"16.9","Cell RNA - SCLC-21H [nTPM]":"12.1","Cell RNA - SH-SY5Y [nTPM]":"30.1","Cell RNA - SiHa [nTPM]":"26.8","Cell RNA - SK-BR-3 [nTPM]":"12.4","Cell RNA - SK-MEL-30 [nTPM]":"13.9","Cell RNA - SuSa [nTPM]":"18.6","Cell RNA - T-47d [nTPM]":"8.8","Cell RNA - THP-1 [nTPM]":"25.1","Cell RNA - TIME [nTPM]":"23.9","Cell RNA - U-138 MG [nTPM]":"27.8","Cell RNA - U-2 OS [nTPM]":"14.2","Cell RNA - U-2197 [nTPM]":"11.7","Cell RNA - U-251 MG [nTPM]":"21.1","Cell RNA - U-266\/70 [nTPM]":"25.6","Cell RNA - U-266\/84 [nTPM]":"9.5","Cell RNA - U-698 [nTPM]":"25.4","Cell RNA - U-87 MG [nTPM]":"11.8","Cell RNA - U-937 [nTPM]":"24.1","Cell RNA - WM-115 [nTPM]":"16.9","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"9.1","Brain RNA - basal ganglia [nTPM]":"9.1","Brain RNA - cerebellum [nTPM]":"9.2","Brain RNA - cerebral cortex [nTPM]":"8.5","Brain RNA - hippocampal formation [nTPM]":"8.4","Brain RNA - hypothalamus [nTPM]":"9.2","Brain RNA - medulla oblongata [nTPM]":"9.5","Brain RNA - midbrain [nTPM]":"10.2","Brain RNA - pons [nTPM]":"8.6","Brain RNA - spinal cord [nTPM]":"10.1","Brain RNA - thalamus [nTPM]":"10.3","Brain RNA - white matter [nTPM]":"9.6","Single Cell Type RNA - Adipocytes [nTPM]":"35.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"22.7","Single Cell Type RNA - Astrocytes [nTPM]":"68.2","Single Cell Type RNA - B-cells [nTPM]":"11.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"21.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"19.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"28.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"24.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"19.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"31.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.3","Single Cell Type RNA - dendritic cells [nTPM]":"18.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"20.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"13.4","Single Cell Type RNA - Early spermatids [nTPM]":"7.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"29.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"59.2","Single Cell Type RNA - Endothelial cells [nTPM]":"30.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"24.0","Single Cell Type RNA - Erythroid cells [nTPM]":"23.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"106.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.5","Single Cell Type RNA - Fibroblasts [nTPM]":"33.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"32.4","Single Cell Type RNA - granulocytes [nTPM]":"14.5","Single Cell Type RNA - Granulosa cells [nTPM]":"16.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"24.3","Single Cell Type RNA - Hepatocytes [nTPM]":"30.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.9","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"92.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.1","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"17.2","Single Cell Type RNA - Langerhans cells [nTPM]":"16.2","Single Cell Type RNA - Late spermatids [nTPM]":"5.6","Single Cell Type RNA - Leydig cells [nTPM]":"20.5","Single Cell Type RNA - Macrophages [nTPM]":"14.2","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"67.5","Single Cell Type RNA - monocytes [nTPM]":"19.4","Single Cell Type RNA - Muller glia cells [nTPM]":"17.7","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"121.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"109.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.8","Single Cell Type RNA - Paneth cells [nTPM]":"7.0","Single Cell Type RNA - Peritubular cells [nTPM]":"24.8","Single Cell Type RNA - Plasma cells [nTPM]":"18.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"48.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"30.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"35.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.9","Single Cell Type RNA - Spermatocytes [nTPM]":"26.2","Single Cell Type RNA - Spermatogonia [nTPM]":"12.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"25.3","Single Cell Type RNA - T-cells [nTPM]":"14.5","Single Cell Type RNA - Theca cells [nTPM]":"21.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.4","Single Cell Type RNA - Urothelial cells [nTPM]":"25.3"},{"Gene":"MICU1","Gene synonym":["CALC","CBARA1","EFHA3","FLJ12684"],"Ensembl":"ENSG00000107745","Gene description":"Mitochondrial calcium uptake 1","Uniprot":["Q9BPX6"],"Chromosome":"10","Position":"72367327-72626191","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Allergen"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"185.5","Inhibitory neurons":"205.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037479","HPA037480"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA037479":"AB_2675495","HPA037480":"AB_10696934"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.66e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-2"},"Tissue RNA - adipose tissue [nTPM]":"30.9","Tissue RNA - adrenal gland [nTPM]":"55.3","Tissue RNA - amygdala [nTPM]":"34.4","Tissue RNA - appendix [nTPM]":"21.2","Tissue RNA - basal ganglia [nTPM]":"37.2","Tissue RNA - bone marrow [nTPM]":"34.2","Tissue RNA - breast [nTPM]":"26.4","Tissue RNA - cerebellum [nTPM]":"51.4","Tissue RNA - cerebral cortex [nTPM]":"47.1","Tissue RNA - cervix [nTPM]":"28.8","Tissue RNA - choroid plexus [nTPM]":"27.8","Tissue RNA - colon [nTPM]":"30.1","Tissue RNA - duodenum [nTPM]":"37.4","Tissue RNA - endometrium 1 [nTPM]":"36.5","Tissue RNA - epididymis [nTPM]":"23.8","Tissue RNA - esophagus [nTPM]":"20.7","Tissue RNA - fallopian tube [nTPM]":"34.6","Tissue RNA - gallbladder [nTPM]":"32.3","Tissue RNA - heart muscle [nTPM]":"43.9","Tissue RNA - hippocampal formation [nTPM]":"37.8","Tissue RNA - hypothalamus [nTPM]":"32.2","Tissue RNA - kidney [nTPM]":"105.3","Tissue RNA - liver [nTPM]":"116.7","Tissue RNA - lung [nTPM]":"29.6","Tissue RNA - lymph node [nTPM]":"20.1","Tissue RNA - medulla oblongata [nTPM]":"32.2","Tissue RNA - midbrain [nTPM]":"30.7","Tissue RNA - ovary [nTPM]":"41.6","Tissue RNA - pancreas [nTPM]":"20.0","Tissue RNA - parathyroid gland [nTPM]":"43.3","Tissue RNA - pituitary gland [nTPM]":"24.4","Tissue RNA - placenta [nTPM]":"23.6","Tissue RNA - pons [nTPM]":"33.7","Tissue RNA - prostate [nTPM]":"24.8","Tissue RNA - rectum [nTPM]":"32.9","Tissue RNA - retina [nTPM]":"31.5","Tissue RNA - salivary gland [nTPM]":"20.8","Tissue RNA - seminal vesicle [nTPM]":"22.3","Tissue RNA - skeletal muscle [nTPM]":"72.2","Tissue RNA - skin 1 [nTPM]":"29.0","Tissue RNA - small intestine [nTPM]":"32.7","Tissue RNA - smooth muscle [nTPM]":"38.4","Tissue RNA - spinal cord [nTPM]":"29.0","Tissue RNA - spleen [nTPM]":"27.0","Tissue RNA - stomach 1 [nTPM]":"43.3","Tissue RNA - testis [nTPM]":"20.2","Tissue RNA - thalamus [nTPM]":"30.4","Tissue RNA - thymus [nTPM]":"26.1","Tissue RNA - thyroid gland [nTPM]":"22.9","Tissue RNA - tongue [nTPM]":"76.9","Tissue RNA - tonsil [nTPM]":"21.6","Tissue RNA - urinary bladder [nTPM]":"30.8","Tissue RNA - vagina [nTPM]":"21.7","Tissue RNA - white matter [nTPM]":"34.1","Cell RNA - A-431 [nTPM]":"42.2","Cell RNA - A549 [nTPM]":"71.8","Cell RNA - AF22 [nTPM]":"45.4","Cell RNA - AN3-CA [nTPM]":"53.3","Cell RNA - ASC diff [nTPM]":"70.8","Cell RNA - ASC TERT1 [nTPM]":"66.6","Cell RNA - BEWO [nTPM]":"20.6","Cell RNA - BJ [nTPM]":"45.8","Cell RNA - BJ hTERT+ [nTPM]":"101.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"65.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"89.8","Cell RNA - CACO-2 [nTPM]":"42.2","Cell RNA - CAPAN-2 [nTPM]":"77.2","Cell RNA - Daudi [nTPM]":"56.8","Cell RNA - EFO-21 [nTPM]":"37.3","Cell RNA - fHDF\/TERT166 [nTPM]":"63.5","Cell RNA - GAMG [nTPM]":"54.0","Cell RNA - HaCaT [nTPM]":"49.1","Cell RNA - HAP1 [nTPM]":"57.7","Cell RNA - HBEC3-KT [nTPM]":"40.7","Cell RNA - HBF TERT88 [nTPM]":"76.9","Cell RNA - HDLM-2 [nTPM]":"51.9","Cell RNA - HEK 293 [nTPM]":"46.6","Cell RNA - HEL [nTPM]":"38.3","Cell RNA - HeLa [nTPM]":"37.1","Cell RNA - Hep G2 [nTPM]":"61.2","Cell RNA - HHSteC [nTPM]":"56.4","Cell RNA - HL-60 [nTPM]":"53.3","Cell RNA - HMC-1 [nTPM]":"40.1","Cell RNA - HSkMC [nTPM]":"66.6","Cell RNA - hTCEpi [nTPM]":"36.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"72.4","Cell RNA - hTERT-HME1 [nTPM]":"66.5","Cell RNA - hTERT-RPE1 [nTPM]":"90.4","Cell RNA - HUVEC TERT2 [nTPM]":"57.7","Cell RNA - JURKAT [nTPM]":"53.4","Cell RNA - K-562 [nTPM]":"60.0","Cell RNA - Karpas-707 [nTPM]":"64.5","Cell RNA - LHCN-M2 [nTPM]":"77.6","Cell RNA - MCF7 [nTPM]":"37.9","Cell RNA - MOLT-4 [nTPM]":"46.7","Cell RNA - NB-4 [nTPM]":"49.9","Cell RNA - NTERA-2 [nTPM]":"19.0","Cell RNA - OE19 [nTPM]":"45.0","Cell RNA - PC-3 [nTPM]":"17.3","Cell RNA - REH [nTPM]":"50.5","Cell RNA - RH-30 [nTPM]":"60.9","Cell RNA - RPMI-8226 [nTPM]":"37.4","Cell RNA - RPTEC TERT1 [nTPM]":"80.8","Cell RNA - RT4 [nTPM]":"31.0","Cell RNA - SCLC-21H [nTPM]":"34.8","Cell RNA - SH-SY5Y [nTPM]":"49.8","Cell RNA - SiHa [nTPM]":"54.2","Cell RNA - SK-BR-3 [nTPM]":"65.9","Cell RNA - SK-MEL-30 [nTPM]":"42.0","Cell RNA - SuSa [nTPM]":"45.2","Cell RNA - T-47d [nTPM]":"39.3","Cell RNA - THP-1 [nTPM]":"50.5","Cell RNA - TIME [nTPM]":"36.2","Cell RNA - U-138 MG [nTPM]":"32.6","Cell RNA - U-2 OS [nTPM]":"50.1","Cell RNA - U-2197 [nTPM]":"65.7","Cell RNA - U-251 MG [nTPM]":"38.4","Cell RNA - U-266\/70 [nTPM]":"33.9","Cell RNA - U-266\/84 [nTPM]":"62.6","Cell RNA - U-698 [nTPM]":"39.2","Cell RNA - U-87 MG [nTPM]":"65.1","Cell RNA - U-937 [nTPM]":"69.6","Cell RNA - WM-115 [nTPM]":"22.5","Blood RNA - basophil [nTPM]":"21.5","Blood RNA - classical monocyte [nTPM]":"60.0","Blood RNA - eosinophil [nTPM]":"110.8","Blood RNA - gdT-cell [nTPM]":"16.8","Blood RNA - intermediate monocyte [nTPM]":"49.8","Blood RNA - MAIT T-cell [nTPM]":"14.7","Blood RNA - memory B-cell [nTPM]":"15.1","Blood RNA - memory CD4 T-cell [nTPM]":"14.7","Blood RNA - memory CD8 T-cell [nTPM]":"15.5","Blood RNA - myeloid DC [nTPM]":"26.0","Blood RNA - naive B-cell [nTPM]":"17.5","Blood RNA - naive CD4 T-cell [nTPM]":"14.4","Blood RNA - naive CD8 T-cell [nTPM]":"12.0","Blood RNA - neutrophil [nTPM]":"48.8","Blood RNA - NK-cell [nTPM]":"15.2","Blood RNA - non-classical monocyte [nTPM]":"54.5","Blood RNA - plasmacytoid DC [nTPM]":"16.5","Blood RNA - T-reg [nTPM]":"15.3","Blood RNA - total PBMC [nTPM]":"35.4","Brain RNA - amygdala [nTPM]":"34.4","Brain RNA - basal ganglia [nTPM]":"37.2","Brain RNA - cerebellum [nTPM]":"51.4","Brain RNA - cerebral cortex [nTPM]":"47.1","Brain RNA - hippocampal formation [nTPM]":"37.8","Brain RNA - hypothalamus [nTPM]":"32.2","Brain RNA - medulla oblongata [nTPM]":"32.2","Brain RNA - midbrain [nTPM]":"30.7","Brain RNA - pons [nTPM]":"33.7","Brain RNA - spinal cord [nTPM]":"29.0","Brain RNA - thalamus [nTPM]":"30.4","Brain RNA - white matter [nTPM]":"34.1","Single Cell Type RNA - Adipocytes [nTPM]":"30.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"54.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"36.0","Single Cell Type RNA - Astrocytes [nTPM]":"47.7","Single Cell Type RNA - B-cells [nTPM]":"23.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"31.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"19.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"35.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"38.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"35.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.7","Single Cell Type RNA - dendritic cells [nTPM]":"16.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"25.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"80.3","Single Cell Type RNA - Ductal cells [nTPM]":"35.6","Single Cell Type RNA - Early spermatids [nTPM]":"10.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"42.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"43.0","Single Cell Type RNA - Endothelial cells [nTPM]":"22.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.4","Single Cell Type RNA - Erythroid cells [nTPM]":"25.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"185.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.8","Single Cell Type RNA - Fibroblasts [nTPM]":"31.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"45.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"48.2","Single Cell Type RNA - granulocytes [nTPM]":"18.3","Single Cell Type RNA - Granulosa cells [nTPM]":"31.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.9","Single Cell Type RNA - Hepatocytes [nTPM]":"60.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"34.8","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"205.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.4","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"36.9","Single Cell Type RNA - Langerhans cells [nTPM]":"13.4","Single Cell Type RNA - Late spermatids [nTPM]":"12.5","Single Cell Type RNA - Leydig cells [nTPM]":"26.8","Single Cell Type RNA - Macrophages [nTPM]":"40.1","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"64.6","Single Cell Type RNA - monocytes [nTPM]":"38.0","Single Cell Type RNA - Muller glia cells [nTPM]":"51.3","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"146.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"97.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"51.4","Single Cell Type RNA - Paneth cells [nTPM]":"24.9","Single Cell Type RNA - Peritubular cells [nTPM]":"25.9","Single Cell Type RNA - Plasma cells [nTPM]":"25.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"29.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"110.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"34.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"33.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"29.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.2","Single Cell Type RNA - Spermatocytes [nTPM]":"54.5","Single Cell Type RNA - Spermatogonia [nTPM]":"40.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"21.5","Single Cell Type RNA - T-cells [nTPM]":"19.0","Single Cell Type RNA - Theca cells [nTPM]":"73.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.6","Single Cell Type RNA - Urothelial cells [nTPM]":"14.2"},{"Gene":"MID1","Gene synonym":["FXY","OS","RNF59","TRIM18"],"Ensembl":"ENSG00000101871","Gene description":"Midline 1","Uniprot":["O15344"],"Chromosome":"X","Position":"10445310-10833654","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"129.3","Basal squamous epithelial cells":"82.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"156.1","AF22":"132.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002878","HPA003715"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus","Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":["Centriolar satellite"],"Subcellular additional location":["Golgi apparatus","Cytosol"],"Antibody RRID":{"HPA002878":null,"HPA003715":"AB_1079384"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.06e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.9","Tissue RNA - adrenal gland [nTPM]":"2.5","Tissue RNA - amygdala [nTPM]":"6.9","Tissue RNA - appendix [nTPM]":"5.0","Tissue RNA - basal ganglia [nTPM]":"7.7","Tissue RNA - bone marrow [nTPM]":"1.7","Tissue RNA - breast [nTPM]":"5.3","Tissue RNA - cerebellum [nTPM]":"17.2","Tissue RNA - cerebral cortex [nTPM]":"5.0","Tissue RNA - cervix [nTPM]":"7.0","Tissue RNA - choroid plexus [nTPM]":"6.5","Tissue RNA - colon [nTPM]":"17.3","Tissue RNA - duodenum [nTPM]":"5.7","Tissue RNA - endometrium 1 [nTPM]":"8.9","Tissue RNA - epididymis [nTPM]":"4.9","Tissue RNA - esophagus [nTPM]":"7.0","Tissue RNA - fallopian tube [nTPM]":"6.4","Tissue RNA - gallbladder [nTPM]":"6.8","Tissue RNA - heart muscle [nTPM]":"9.3","Tissue RNA - hippocampal formation [nTPM]":"7.0","Tissue RNA - hypothalamus [nTPM]":"4.9","Tissue RNA - kidney [nTPM]":"7.3","Tissue RNA - liver [nTPM]":"4.2","Tissue RNA - lung [nTPM]":"6.5","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"3.6","Tissue RNA - midbrain [nTPM]":"10.4","Tissue RNA - ovary [nTPM]":"4.4","Tissue RNA - pancreas [nTPM]":"3.5","Tissue RNA - parathyroid gland [nTPM]":"2.8","Tissue RNA - pituitary gland [nTPM]":"4.2","Tissue RNA - placenta [nTPM]":"6.2","Tissue RNA - pons [nTPM]":"4.9","Tissue RNA - prostate [nTPM]":"10.4","Tissue RNA - rectum [nTPM]":"10.6","Tissue RNA - retina [nTPM]":"12.3","Tissue RNA - salivary gland [nTPM]":"4.9","Tissue RNA - seminal vesicle [nTPM]":"12.9","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"2.9","Tissue RNA - small intestine [nTPM]":"5.8","Tissue RNA - smooth muscle [nTPM]":"12.3","Tissue RNA - spinal cord [nTPM]":"2.1","Tissue RNA - spleen [nTPM]":"1.0","Tissue RNA - stomach 1 [nTPM]":"3.8","Tissue RNA - testis [nTPM]":"3.6","Tissue RNA - thalamus [nTPM]":"8.2","Tissue RNA - thymus [nTPM]":"2.3","Tissue RNA - thyroid gland [nTPM]":"4.2","Tissue RNA - tongue [nTPM]":"2.2","Tissue RNA - tonsil [nTPM]":"3.1","Tissue RNA - urinary bladder [nTPM]":"11.7","Tissue RNA - vagina [nTPM]":"6.2","Tissue RNA - white matter [nTPM]":"4.4","Cell RNA - A-431 [nTPM]":"33.2","Cell RNA - A549 [nTPM]":"156.1","Cell RNA - AF22 [nTPM]":"132.5","Cell RNA - AN3-CA [nTPM]":"16.7","Cell RNA - ASC diff [nTPM]":"8.1","Cell RNA - ASC TERT1 [nTPM]":"9.2","Cell RNA - BEWO [nTPM]":"14.6","Cell RNA - BJ [nTPM]":"16.2","Cell RNA - BJ hTERT+ [nTPM]":"17.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.7","Cell RNA - CACO-2 [nTPM]":"31.0","Cell RNA - CAPAN-2 [nTPM]":"9.7","Cell RNA - Daudi [nTPM]":"10.6","Cell RNA - EFO-21 [nTPM]":"6.5","Cell RNA - fHDF\/TERT166 [nTPM]":"21.9","Cell RNA - GAMG [nTPM]":"58.4","Cell RNA - HaCaT [nTPM]":"22.5","Cell RNA - HAP1 [nTPM]":"11.0","Cell RNA - HBEC3-KT [nTPM]":"15.1","Cell RNA - HBF TERT88 [nTPM]":"23.0","Cell RNA - HDLM-2 [nTPM]":"1.3","Cell RNA - HEK 293 [nTPM]":"11.0","Cell RNA - HEL [nTPM]":"2.7","Cell RNA - HeLa [nTPM]":"24.3","Cell RNA - Hep G2 [nTPM]":"1.1","Cell RNA - HHSteC [nTPM]":"2.8","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"1.2","Cell RNA - HSkMC [nTPM]":"12.1","Cell RNA - hTCEpi [nTPM]":"7.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.1","Cell RNA - hTERT-HME1 [nTPM]":"15.8","Cell RNA - hTERT-RPE1 [nTPM]":"20.4","Cell RNA - HUVEC TERT2 [nTPM]":"23.1","Cell RNA - JURKAT [nTPM]":"5.1","Cell RNA - K-562 [nTPM]":"2.1","Cell RNA - Karpas-707 [nTPM]":"3.2","Cell RNA - LHCN-M2 [nTPM]":"9.6","Cell RNA - MCF7 [nTPM]":"8.0","Cell RNA - MOLT-4 [nTPM]":"5.3","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"32.7","Cell RNA - OE19 [nTPM]":"5.1","Cell RNA - PC-3 [nTPM]":"10.0","Cell RNA - REH [nTPM]":"3.9","Cell RNA - RH-30 [nTPM]":"28.9","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"18.7","Cell RNA - RT4 [nTPM]":"36.2","Cell RNA - SCLC-21H [nTPM]":"7.1","Cell RNA - SH-SY5Y [nTPM]":"3.5","Cell RNA - SiHa [nTPM]":"7.4","Cell RNA - SK-BR-3 [nTPM]":"23.5","Cell RNA - SK-MEL-30 [nTPM]":"10.1","Cell RNA - SuSa [nTPM]":"42.7","Cell RNA - T-47d [nTPM]":"19.2","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"13.7","Cell RNA - U-138 MG [nTPM]":"7.2","Cell RNA - U-2 OS [nTPM]":"1.0","Cell RNA - U-2197 [nTPM]":"34.1","Cell RNA - U-251 MG [nTPM]":"17.0","Cell RNA - U-266\/70 [nTPM]":"2.8","Cell RNA - U-266\/84 [nTPM]":"1.2","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"13.5","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"31.3","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"6.9","Brain RNA - basal ganglia [nTPM]":"7.7","Brain RNA - cerebellum [nTPM]":"17.2","Brain RNA - cerebral cortex [nTPM]":"5.0","Brain RNA - hippocampal formation [nTPM]":"7.0","Brain RNA - hypothalamus [nTPM]":"4.9","Brain RNA - medulla oblongata [nTPM]":"3.6","Brain RNA - midbrain [nTPM]":"10.4","Brain RNA - pons [nTPM]":"4.9","Brain RNA - spinal cord [nTPM]":"2.1","Brain RNA - thalamus [nTPM]":"8.2","Brain RNA - white matter [nTPM]":"4.4","Single Cell Type RNA - Adipocytes [nTPM]":"16.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.7","Single Cell Type RNA - Astrocytes [nTPM]":"129.3","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"21.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"31.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"24.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"82.6","Single Cell Type RNA - Bipolar cells [nTPM]":"10.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"19.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.1","Single Cell Type RNA - dendritic cells [nTPM]":"1.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"22.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"13.4","Single Cell Type RNA - Early spermatids [nTPM]":"2.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"39.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.9","Single Cell Type RNA - Endothelial cells [nTPM]":"25.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.1","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.9","Single Cell Type RNA - Fibroblasts [nTPM]":"16.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"38.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"13.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"69.9","Single Cell Type RNA - Hepatocytes [nTPM]":"4.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.5","Single Cell Type RNA - Horizontal cells [nTPM]":"69.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"44.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.5","Single Cell Type RNA - Langerhans cells [nTPM]":"5.8","Single Cell Type RNA - Late spermatids [nTPM]":"7.9","Single Cell Type RNA - Leydig cells [nTPM]":"30.1","Single Cell Type RNA - Macrophages [nTPM]":"1.2","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"37.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"66.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"59.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.3","Single Cell Type RNA - Paneth cells [nTPM]":"17.2","Single Cell Type RNA - Peritubular cells [nTPM]":"41.3","Single Cell Type RNA - Plasma cells [nTPM]":"0.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"2.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"36.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.0","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"9.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.0","Single Cell Type RNA - Urothelial cells [nTPM]":"49.2"},{"Gene":"MID2","Gene synonym":["FXY2","MRX101","RNF60","TRIM1"],"Ensembl":"ENSG00000080561","Gene description":"Midline 2","Uniprot":["Q9UJV3"],"Chromosome":"X","Position":"107825755-107931637","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"14.5","Inhibitory neurons":"21.5","Urothelial cells":"11.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"T-cells":"1.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HUVEC TERT2":"41.5","Karpas-707":"35.5","MCF7":"26.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.73e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-3"},"Tissue RNA - adipose tissue [nTPM]":"11.2","Tissue RNA - adrenal gland [nTPM]":"9.2","Tissue RNA - amygdala [nTPM]":"5.2","Tissue RNA - appendix [nTPM]":"3.9","Tissue RNA - basal ganglia [nTPM]":"6.1","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"7.2","Tissue RNA - cerebellum [nTPM]":"4.4","Tissue RNA - cerebral cortex [nTPM]":"4.2","Tissue RNA - cervix [nTPM]":"8.3","Tissue RNA - choroid plexus [nTPM]":"4.2","Tissue RNA - colon [nTPM]":"6.0","Tissue RNA - duodenum [nTPM]":"1.8","Tissue RNA - endometrium 1 [nTPM]":"9.4","Tissue RNA - epididymis [nTPM]":"8.0","Tissue RNA - esophagus [nTPM]":"13.6","Tissue RNA - fallopian tube [nTPM]":"8.8","Tissue RNA - gallbladder [nTPM]":"7.7","Tissue RNA - heart muscle [nTPM]":"3.1","Tissue RNA - hippocampal formation [nTPM]":"3.5","Tissue RNA - hypothalamus [nTPM]":"12.1","Tissue RNA - kidney [nTPM]":"6.0","Tissue RNA - liver [nTPM]":"5.4","Tissue RNA - lung [nTPM]":"6.4","Tissue RNA - lymph node [nTPM]":"4.4","Tissue RNA - medulla oblongata [nTPM]":"7.4","Tissue RNA - midbrain [nTPM]":"7.1","Tissue RNA - ovary [nTPM]":"9.3","Tissue RNA - pancreas [nTPM]":"9.6","Tissue RNA - parathyroid gland [nTPM]":"12.9","Tissue RNA - pituitary gland [nTPM]":"3.2","Tissue RNA - placenta [nTPM]":"4.4","Tissue RNA - pons [nTPM]":"9.1","Tissue RNA - prostate [nTPM]":"10.3","Tissue RNA - rectum [nTPM]":"3.6","Tissue RNA - retina [nTPM]":"14.8","Tissue RNA - salivary gland [nTPM]":"11.1","Tissue RNA - seminal vesicle [nTPM]":"9.6","Tissue RNA - skeletal muscle [nTPM]":"12.9","Tissue RNA - skin 1 [nTPM]":"9.6","Tissue RNA - small intestine [nTPM]":"2.6","Tissue RNA - smooth muscle [nTPM]":"15.8","Tissue RNA - spinal cord [nTPM]":"6.3","Tissue RNA - spleen [nTPM]":"3.8","Tissue RNA - stomach 1 [nTPM]":"4.4","Tissue RNA - testis [nTPM]":"2.1","Tissue RNA - thalamus [nTPM]":"9.0","Tissue RNA - thymus [nTPM]":"2.3","Tissue RNA - thyroid gland [nTPM]":"13.2","Tissue RNA - tongue [nTPM]":"18.5","Tissue RNA - tonsil [nTPM]":"5.2","Tissue RNA - urinary bladder [nTPM]":"10.6","Tissue RNA - vagina [nTPM]":"7.5","Tissue RNA - white matter [nTPM]":"4.8","Cell RNA - A-431 [nTPM]":"8.4","Cell RNA - A549 [nTPM]":"7.1","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"11.2","Cell RNA - ASC diff [nTPM]":"8.8","Cell RNA - ASC TERT1 [nTPM]":"12.3","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"5.9","Cell RNA - BJ hTERT+ [nTPM]":"15.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.6","Cell RNA - CACO-2 [nTPM]":"0.6","Cell RNA - CAPAN-2 [nTPM]":"1.5","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"7.5","Cell RNA - fHDF\/TERT166 [nTPM]":"11.7","Cell RNA - GAMG [nTPM]":"8.3","Cell RNA - HaCaT [nTPM]":"5.2","Cell RNA - HAP1 [nTPM]":"4.1","Cell RNA - HBEC3-KT [nTPM]":"12.1","Cell RNA - HBF TERT88 [nTPM]":"1.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"5.5","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"4.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"13.5","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"8.0","Cell RNA - hTCEpi [nTPM]":"13.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"14.5","Cell RNA - hTERT-RPE1 [nTPM]":"9.1","Cell RNA - HUVEC TERT2 [nTPM]":"41.5","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"35.5","Cell RNA - LHCN-M2 [nTPM]":"5.6","Cell RNA - MCF7 [nTPM]":"26.8","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.2","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"13.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"3.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"6.3","Cell RNA - RT4 [nTPM]":"7.5","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"12.6","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"18.6","Cell RNA - SuSa [nTPM]":"3.9","Cell RNA - T-47d [nTPM]":"4.6","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"8.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"2.1","Cell RNA - U-2197 [nTPM]":"9.9","Cell RNA - U-251 MG [nTPM]":"2.8","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"1.3","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.6","Blood RNA - naive CD8 T-cell [nTPM]":"1.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"5.2","Brain RNA - basal ganglia [nTPM]":"6.1","Brain RNA - cerebellum [nTPM]":"4.4","Brain RNA - cerebral cortex [nTPM]":"4.2","Brain RNA - hippocampal formation [nTPM]":"3.5","Brain RNA - hypothalamus [nTPM]":"12.1","Brain RNA - medulla oblongata [nTPM]":"7.4","Brain RNA - midbrain [nTPM]":"7.1","Brain RNA - pons [nTPM]":"9.1","Brain RNA - spinal cord [nTPM]":"6.3","Brain RNA - thalamus [nTPM]":"9.0","Brain RNA - white matter [nTPM]":"4.8","Single Cell Type RNA - Adipocytes [nTPM]":"3.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"8.1","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"1.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.8","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.7","Single Cell Type RNA - Endothelial cells [nTPM]":"2.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"1.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"1.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.7","Single Cell Type RNA - Theca cells [nTPM]":"0.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"11.4"},{"Gene":"MIF","Gene synonym":["GIF","GLIF"],"Ensembl":"ENSG00000240972","Gene description":"Macrophage migration inhibitory factor","Uniprot":["P14174"],"Chromosome":"22","Position":"23894383-23895227","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Cytokine","Isomerase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal tubular cells":"2032.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEK 293":"4974.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003868","CAB005284"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":13800000,"Blood concentration - Conc. blood MS [pg\/L]":"5000000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB005284":"AB_648587","HPA003868":"AB_1079290"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Tissue RNA - adipose tissue [nTPM]":"233.3","Tissue RNA - adrenal gland [nTPM]":"467.9","Tissue RNA - amygdala [nTPM]":"195.8","Tissue RNA - appendix [nTPM]":"119.5","Tissue RNA - basal ganglia [nTPM]":"200.0","Tissue RNA - bone marrow [nTPM]":"146.0","Tissue RNA - breast [nTPM]":"223.3","Tissue RNA - cerebellum [nTPM]":"209.3","Tissue RNA - cerebral cortex [nTPM]":"450.0","Tissue RNA - cervix [nTPM]":"235.0","Tissue RNA - choroid plexus [nTPM]":"204.3","Tissue RNA - colon [nTPM]":"194.3","Tissue RNA - duodenum [nTPM]":"98.9","Tissue RNA - endometrium 1 [nTPM]":"205.3","Tissue RNA - epididymis [nTPM]":"49.8","Tissue RNA - esophagus [nTPM]":"514.2","Tissue RNA - fallopian tube [nTPM]":"219.4","Tissue RNA - gallbladder [nTPM]":"20.9","Tissue RNA - heart muscle [nTPM]":"290.8","Tissue RNA - hippocampal formation [nTPM]":"245.2","Tissue RNA - hypothalamus [nTPM]":"289.7","Tissue RNA - kidney [nTPM]":"530.3","Tissue RNA - liver [nTPM]":"484.6","Tissue RNA - lung [nTPM]":"208.2","Tissue RNA - lymph node [nTPM]":"61.5","Tissue RNA - medulla oblongata [nTPM]":"225.2","Tissue RNA - midbrain [nTPM]":"224.7","Tissue RNA - ovary [nTPM]":"223.7","Tissue RNA - pancreas [nTPM]":"255.7","Tissue RNA - parathyroid gland [nTPM]":"127.8","Tissue RNA - pituitary gland [nTPM]":"368.0","Tissue RNA - placenta [nTPM]":"100.4","Tissue RNA - pons [nTPM]":"217.2","Tissue RNA - prostate [nTPM]":"318.7","Tissue RNA - rectum [nTPM]":"35.2","Tissue RNA - retina [nTPM]":"23.8","Tissue RNA - salivary gland [nTPM]":"233.6","Tissue RNA - seminal vesicle [nTPM]":"132.8","Tissue RNA - skeletal muscle [nTPM]":"99.3","Tissue RNA - skin 1 [nTPM]":"302.5","Tissue RNA - small intestine [nTPM]":"171.7","Tissue RNA - smooth muscle [nTPM]":"43.4","Tissue RNA - spinal cord [nTPM]":"250.8","Tissue RNA - spleen [nTPM]":"204.5","Tissue RNA - stomach 1 [nTPM]":"230.7","Tissue RNA - testis [nTPM]":"113.5","Tissue RNA - thalamus [nTPM]":"204.2","Tissue RNA - thymus [nTPM]":"65.0","Tissue RNA - thyroid gland [nTPM]":"274.0","Tissue RNA - tongue [nTPM]":"19.5","Tissue RNA - tonsil [nTPM]":"46.2","Tissue RNA - urinary bladder [nTPM]":"255.8","Tissue RNA - vagina [nTPM]":"316.7","Tissue RNA - white matter [nTPM]":"369.4","Cell RNA - A-431 [nTPM]":"1698.3","Cell RNA - A549 [nTPM]":"605.3","Cell RNA - AF22 [nTPM]":"122.2","Cell RNA - AN3-CA [nTPM]":"499.0","Cell RNA - ASC diff [nTPM]":"58.9","Cell RNA - ASC TERT1 [nTPM]":"111.3","Cell RNA - BEWO [nTPM]":"590.7","Cell RNA - BJ [nTPM]":"581.2","Cell RNA - BJ hTERT+ [nTPM]":"154.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"298.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"382.1","Cell RNA - CACO-2 [nTPM]":"526.4","Cell RNA - CAPAN-2 [nTPM]":"364.4","Cell RNA - Daudi [nTPM]":"761.3","Cell RNA - EFO-21 [nTPM]":"499.8","Cell RNA - fHDF\/TERT166 [nTPM]":"83.1","Cell RNA - GAMG [nTPM]":"115.2","Cell RNA - HaCaT [nTPM]":"788.1","Cell RNA - HAP1 [nTPM]":"155.0","Cell RNA - HBEC3-KT [nTPM]":"546.8","Cell RNA - HBF TERT88 [nTPM]":"51.5","Cell RNA - HDLM-2 [nTPM]":"642.2","Cell RNA - HEK 293 [nTPM]":"4974.4","Cell RNA - HEL [nTPM]":"286.2","Cell RNA - HeLa [nTPM]":"534.6","Cell RNA - Hep G2 [nTPM]":"1126.5","Cell RNA - HHSteC [nTPM]":"225.3","Cell RNA - HL-60 [nTPM]":"1077.2","Cell RNA - HMC-1 [nTPM]":"758.6","Cell RNA - HSkMC [nTPM]":"230.9","Cell RNA - hTCEpi [nTPM]":"354.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"173.8","Cell RNA - hTERT-HME1 [nTPM]":"103.5","Cell RNA - hTERT-RPE1 [nTPM]":"248.8","Cell RNA - HUVEC TERT2 [nTPM]":"241.3","Cell RNA - JURKAT [nTPM]":"589.4","Cell RNA - K-562 [nTPM]":"466.9","Cell RNA - Karpas-707 [nTPM]":"540.1","Cell RNA - LHCN-M2 [nTPM]":"122.2","Cell RNA - MCF7 [nTPM]":"1476.0","Cell RNA - MOLT-4 [nTPM]":"827.0","Cell RNA - NB-4 [nTPM]":"2345.5","Cell RNA - NTERA-2 [nTPM]":"532.8","Cell RNA - OE19 [nTPM]":"488.6","Cell RNA - PC-3 [nTPM]":"2365.8","Cell RNA - REH [nTPM]":"1040.4","Cell RNA - RH-30 [nTPM]":"127.9","Cell RNA - RPMI-8226 [nTPM]":"2398.8","Cell RNA - RPTEC TERT1 [nTPM]":"294.7","Cell RNA - RT4 [nTPM]":"179.6","Cell RNA - SCLC-21H [nTPM]":"1080.9","Cell RNA - SH-SY5Y [nTPM]":"1290.4","Cell RNA - SiHa [nTPM]":"380.3","Cell RNA - SK-BR-3 [nTPM]":"531.9","Cell RNA - SK-MEL-30 [nTPM]":"1374.7","Cell RNA - SuSa [nTPM]":"37.6","Cell RNA - T-47d [nTPM]":"671.2","Cell RNA - THP-1 [nTPM]":"442.6","Cell RNA - TIME [nTPM]":"424.7","Cell RNA - U-138 MG [nTPM]":"232.5","Cell RNA - U-2 OS [nTPM]":"1227.9","Cell RNA - U-2197 [nTPM]":"127.3","Cell RNA - U-251 MG [nTPM]":"9.9","Cell RNA - U-266\/70 [nTPM]":"1647.2","Cell RNA - U-266\/84 [nTPM]":"732.5","Cell RNA - U-698 [nTPM]":"1020.9","Cell RNA - U-87 MG [nTPM]":"967.5","Cell RNA - U-937 [nTPM]":"484.6","Cell RNA - WM-115 [nTPM]":"477.9","Blood RNA - basophil [nTPM]":"484.2","Blood RNA - classical monocyte [nTPM]":"543.5","Blood RNA - eosinophil [nTPM]":"443.5","Blood RNA - gdT-cell [nTPM]":"872.4","Blood RNA - intermediate monocyte [nTPM]":"579.5","Blood RNA - MAIT T-cell [nTPM]":"1250.8","Blood RNA - memory B-cell [nTPM]":"1527.9","Blood RNA - memory CD4 T-cell [nTPM]":"1221.7","Blood RNA - memory CD8 T-cell [nTPM]":"983.3","Blood RNA - myeloid DC [nTPM]":"796.9","Blood RNA - naive B-cell [nTPM]":"1378.9","Blood RNA - naive CD4 T-cell [nTPM]":"1040.4","Blood RNA - naive CD8 T-cell [nTPM]":"928.4","Blood RNA - neutrophil [nTPM]":"166.8","Blood RNA - NK-cell [nTPM]":"1158.9","Blood RNA - non-classical monocyte [nTPM]":"383.3","Blood RNA - plasmacytoid DC [nTPM]":"977.1","Blood RNA - T-reg [nTPM]":"1258.3","Blood RNA - total PBMC [nTPM]":"1803.3","Brain RNA - amygdala [nTPM]":"195.8","Brain RNA - basal ganglia [nTPM]":"200.0","Brain RNA - cerebellum [nTPM]":"209.3","Brain RNA - cerebral cortex [nTPM]":"450.0","Brain RNA - hippocampal formation [nTPM]":"245.2","Brain RNA - hypothalamus [nTPM]":"289.7","Brain RNA - medulla oblongata [nTPM]":"225.2","Brain RNA - midbrain [nTPM]":"224.7","Brain RNA - pons [nTPM]":"217.2","Brain RNA - spinal cord [nTPM]":"250.8","Brain RNA - thalamus [nTPM]":"204.2","Brain RNA - white matter [nTPM]":"369.4","Single Cell Type RNA - Adipocytes [nTPM]":"161.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"157.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"199.4","Single Cell Type RNA - Astrocytes [nTPM]":"21.5","Single Cell Type RNA - B-cells [nTPM]":"433.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"672.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"295.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1134.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1027.2","Single Cell Type RNA - Bipolar cells [nTPM]":"28.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"856.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"778.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"479.0","Single Cell Type RNA - Club cells [nTPM]":"489.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"693.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"462.7","Single Cell Type RNA - dendritic cells [nTPM]":"171.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"317.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"1649.4","Single Cell Type RNA - Ductal cells [nTPM]":"859.0","Single Cell Type RNA - Early spermatids [nTPM]":"190.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"733.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"485.3","Single Cell Type RNA - Endothelial cells [nTPM]":"248.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"348.9","Single Cell Type RNA - Erythroid cells [nTPM]":"455.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"377.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"885.0","Single Cell Type RNA - Fibroblasts [nTPM]":"336.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"606.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"844.3","Single Cell Type RNA - granulocytes [nTPM]":"180.3","Single Cell Type RNA - Granulosa cells [nTPM]":"192.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"261.6","Single Cell Type RNA - Hepatocytes [nTPM]":"885.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"278.8","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"432.5","Single Cell Type RNA - Ionocytes [nTPM]":"697.8","Single Cell Type RNA - Kupffer cells [nTPM]":"207.7","Single Cell Type RNA - Langerhans cells [nTPM]":"505.2","Single Cell Type RNA - Late spermatids [nTPM]":"153.9","Single Cell Type RNA - Leydig cells [nTPM]":"336.1","Single Cell Type RNA - Macrophages [nTPM]":"232.6","Single Cell Type RNA - Melanocytes [nTPM]":"773.7","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"217.0","Single Cell Type RNA - Muller glia cells [nTPM]":"59.5","Single Cell Type RNA - NK-cells [nTPM]":"155.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"52.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"649.9","Single Cell Type RNA - Paneth cells [nTPM]":"360.4","Single Cell Type RNA - Peritubular cells [nTPM]":"302.8","Single Cell Type RNA - Plasma cells [nTPM]":"1337.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"269.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"476.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2032.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"404.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"33.2","Single Cell Type RNA - Sertoli cells [nTPM]":"138.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"338.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"349.7","Single Cell Type RNA - Spermatocytes [nTPM]":"21.3","Single Cell Type RNA - Spermatogonia [nTPM]":"124.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1511.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"758.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"686.0","Single Cell Type RNA - T-cells [nTPM]":"386.3","Single Cell Type RNA - Theca cells [nTPM]":"227.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"473.0","Single Cell Type RNA - Urothelial cells [nTPM]":"256.1"},{"Gene":"MINPP1","Gene synonym":["MIPP"],"Ensembl":"ENSG00000107789","Gene description":"Multiple inositol-polyphosphate phosphatase 1","Uniprot":["Q9UNW1"],"Chromosome":"10","Position":"87504875-87553461","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Erythroid cells":"288.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026859"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"370000000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026859":"AB_1853961"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.98e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.5","Tissue RNA - adrenal gland [nTPM]":"21.3","Tissue RNA - amygdala [nTPM]":"6.6","Tissue RNA - appendix [nTPM]":"7.2","Tissue RNA - basal ganglia [nTPM]":"6.7","Tissue RNA - bone marrow [nTPM]":"31.1","Tissue RNA - breast [nTPM]":"9.4","Tissue RNA - cerebellum [nTPM]":"6.9","Tissue RNA - cerebral cortex [nTPM]":"9.1","Tissue RNA - cervix [nTPM]":"8.8","Tissue RNA - choroid plexus [nTPM]":"9.4","Tissue RNA - colon [nTPM]":"12.6","Tissue RNA - duodenum [nTPM]":"17.6","Tissue RNA - endometrium 1 [nTPM]":"7.0","Tissue RNA - epididymis [nTPM]":"10.0","Tissue RNA - esophagus [nTPM]":"3.6","Tissue RNA - fallopian tube [nTPM]":"8.5","Tissue RNA - gallbladder [nTPM]":"8.4","Tissue RNA - heart muscle [nTPM]":"5.8","Tissue RNA - hippocampal formation [nTPM]":"6.8","Tissue RNA - hypothalamus [nTPM]":"8.0","Tissue RNA - kidney [nTPM]":"17.5","Tissue RNA - liver [nTPM]":"29.1","Tissue RNA - lung [nTPM]":"8.3","Tissue RNA - lymph node [nTPM]":"7.7","Tissue RNA - medulla oblongata [nTPM]":"6.4","Tissue RNA - midbrain [nTPM]":"6.8","Tissue RNA - ovary [nTPM]":"8.8","Tissue RNA - pancreas [nTPM]":"11.9","Tissue RNA - parathyroid gland [nTPM]":"9.0","Tissue RNA - pituitary gland [nTPM]":"8.1","Tissue RNA - placenta [nTPM]":"18.9","Tissue RNA - pons [nTPM]":"6.4","Tissue RNA - prostate [nTPM]":"11.7","Tissue RNA - rectum [nTPM]":"12.9","Tissue RNA - retina [nTPM]":"11.9","Tissue RNA - salivary gland [nTPM]":"6.9","Tissue RNA - seminal vesicle [nTPM]":"7.6","Tissue RNA - skeletal muscle [nTPM]":"4.9","Tissue RNA - skin 1 [nTPM]":"9.1","Tissue RNA - small intestine [nTPM]":"13.6","Tissue RNA - smooth muscle [nTPM]":"7.6","Tissue RNA - spinal cord [nTPM]":"6.9","Tissue RNA - spleen [nTPM]":"6.9","Tissue RNA - stomach 1 [nTPM]":"8.5","Tissue RNA - testis [nTPM]":"7.9","Tissue RNA - thalamus [nTPM]":"7.7","Tissue RNA - thymus [nTPM]":"8.1","Tissue RNA - thyroid gland [nTPM]":"11.6","Tissue RNA - tongue [nTPM]":"5.7","Tissue RNA - tonsil [nTPM]":"7.0","Tissue RNA - urinary bladder [nTPM]":"8.6","Tissue RNA - vagina [nTPM]":"5.7","Tissue RNA - white matter [nTPM]":"7.4","Cell RNA - A-431 [nTPM]":"18.6","Cell RNA - A549 [nTPM]":"28.1","Cell RNA - AF22 [nTPM]":"28.1","Cell RNA - AN3-CA [nTPM]":"40.9","Cell RNA - ASC diff [nTPM]":"46.4","Cell RNA - ASC TERT1 [nTPM]":"38.1","Cell RNA - BEWO [nTPM]":"23.2","Cell RNA - BJ [nTPM]":"29.5","Cell RNA - BJ hTERT+ [nTPM]":"51.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"28.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"38.3","Cell RNA - CACO-2 [nTPM]":"15.0","Cell RNA - CAPAN-2 [nTPM]":"35.5","Cell RNA - Daudi [nTPM]":"16.4","Cell RNA - EFO-21 [nTPM]":"27.0","Cell RNA - fHDF\/TERT166 [nTPM]":"35.9","Cell RNA - GAMG [nTPM]":"19.4","Cell RNA - HaCaT [nTPM]":"28.2","Cell RNA - HAP1 [nTPM]":"29.9","Cell RNA - HBEC3-KT [nTPM]":"27.1","Cell RNA - HBF TERT88 [nTPM]":"33.2","Cell RNA - HDLM-2 [nTPM]":"37.1","Cell RNA - HEK 293 [nTPM]":"35.7","Cell RNA - HEL [nTPM]":"41.1","Cell RNA - HeLa [nTPM]":"10.4","Cell RNA - Hep G2 [nTPM]":"55.7","Cell RNA - HHSteC [nTPM]":"34.6","Cell RNA - HL-60 [nTPM]":"18.0","Cell RNA - HMC-1 [nTPM]":"36.0","Cell RNA - HSkMC [nTPM]":"33.7","Cell RNA - hTCEpi [nTPM]":"34.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.6","Cell RNA - hTERT-HME1 [nTPM]":"19.5","Cell RNA - hTERT-RPE1 [nTPM]":"52.5","Cell RNA - HUVEC TERT2 [nTPM]":"37.0","Cell RNA - JURKAT [nTPM]":"14.3","Cell RNA - K-562 [nTPM]":"24.5","Cell RNA - Karpas-707 [nTPM]":"75.9","Cell RNA - LHCN-M2 [nTPM]":"34.4","Cell RNA - MCF7 [nTPM]":"13.8","Cell RNA - MOLT-4 [nTPM]":"11.9","Cell RNA - NB-4 [nTPM]":"25.6","Cell RNA - NTERA-2 [nTPM]":"20.0","Cell RNA - OE19 [nTPM]":"14.2","Cell RNA - PC-3 [nTPM]":"20.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"15.8","Cell RNA - RPMI-8226 [nTPM]":"11.0","Cell RNA - RPTEC TERT1 [nTPM]":"38.5","Cell RNA - RT4 [nTPM]":"10.4","Cell RNA - SCLC-21H [nTPM]":"10.2","Cell RNA - SH-SY5Y [nTPM]":"31.5","Cell RNA - SiHa [nTPM]":"28.1","Cell RNA - SK-BR-3 [nTPM]":"5.9","Cell RNA - SK-MEL-30 [nTPM]":"51.5","Cell RNA - SuSa [nTPM]":"31.5","Cell RNA - T-47d [nTPM]":"16.7","Cell RNA - THP-1 [nTPM]":"14.7","Cell RNA - TIME [nTPM]":"32.4","Cell RNA - U-138 MG [nTPM]":"18.3","Cell RNA - U-2 OS [nTPM]":"21.9","Cell RNA - U-2197 [nTPM]":"22.1","Cell RNA - U-251 MG [nTPM]":"28.7","Cell RNA - U-266\/70 [nTPM]":"24.5","Cell RNA - U-266\/84 [nTPM]":"27.1","Cell RNA - U-698 [nTPM]":"4.2","Cell RNA - U-87 MG [nTPM]":"29.3","Cell RNA - U-937 [nTPM]":"26.8","Cell RNA - WM-115 [nTPM]":"13.7","Blood RNA - basophil [nTPM]":"10.5","Blood RNA - classical monocyte [nTPM]":"10.8","Blood RNA - eosinophil [nTPM]":"4.9","Blood RNA - gdT-cell [nTPM]":"11.5","Blood RNA - intermediate monocyte [nTPM]":"13.8","Blood RNA - MAIT T-cell [nTPM]":"10.1","Blood RNA - memory B-cell [nTPM]":"8.7","Blood RNA - memory CD4 T-cell [nTPM]":"10.8","Blood RNA - memory CD8 T-cell [nTPM]":"13.0","Blood RNA - myeloid DC [nTPM]":"14.3","Blood RNA - naive B-cell [nTPM]":"8.2","Blood RNA - naive CD4 T-cell [nTPM]":"10.2","Blood RNA - naive CD8 T-cell [nTPM]":"11.4","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"11.7","Blood RNA - non-classical monocyte [nTPM]":"12.5","Blood RNA - plasmacytoid DC [nTPM]":"8.2","Blood RNA - T-reg [nTPM]":"17.3","Blood RNA - total PBMC [nTPM]":"10.5","Brain RNA - amygdala [nTPM]":"6.6","Brain RNA - basal ganglia [nTPM]":"6.7","Brain RNA - cerebellum [nTPM]":"6.9","Brain RNA - cerebral cortex [nTPM]":"9.1","Brain RNA - hippocampal formation [nTPM]":"6.8","Brain RNA - hypothalamus [nTPM]":"8.0","Brain RNA - medulla oblongata [nTPM]":"6.4","Brain RNA - midbrain [nTPM]":"6.8","Brain RNA - pons [nTPM]":"6.4","Brain RNA - spinal cord [nTPM]":"6.9","Brain RNA - thalamus [nTPM]":"7.7","Brain RNA - white matter [nTPM]":"7.4","Single Cell Type RNA - Adipocytes [nTPM]":"11.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.8","Single Cell Type RNA - Astrocytes [nTPM]":"9.1","Single Cell Type RNA - B-cells [nTPM]":"8.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"25.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"14.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"16.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.4","Single Cell Type RNA - dendritic cells [nTPM]":"4.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"17.2","Single Cell Type RNA - Early spermatids [nTPM]":"15.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.4","Single Cell Type RNA - Endothelial cells [nTPM]":"10.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"288.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.2","Single Cell Type RNA - Fibroblasts [nTPM]":"17.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.7","Single Cell Type RNA - granulocytes [nTPM]":"24.7","Single Cell Type RNA - Granulosa cells [nTPM]":"17.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.4","Single Cell Type RNA - Hepatocytes [nTPM]":"58.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.9","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"25.5","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"16.0","Single Cell Type RNA - Langerhans cells [nTPM]":"5.8","Single Cell Type RNA - Late spermatids [nTPM]":"4.0","Single Cell Type RNA - Leydig cells [nTPM]":"9.3","Single Cell Type RNA - Macrophages [nTPM]":"8.7","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"11.7","Single Cell Type RNA - Muller glia cells [nTPM]":"11.1","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"25.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.5","Single Cell Type RNA - Paneth cells [nTPM]":"17.2","Single Cell Type RNA - Peritubular cells [nTPM]":"8.2","Single Cell Type RNA - Plasma cells [nTPM]":"18.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"26.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.1","Single Cell Type RNA - Spermatocytes [nTPM]":"10.6","Single Cell Type RNA - Spermatogonia [nTPM]":"12.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.1","Single Cell Type RNA - T-cells [nTPM]":"8.2","Single Cell Type RNA - Theca cells [nTPM]":"13.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.6","Single Cell Type RNA - Urothelial cells [nTPM]":"4.4"},{"Gene":"MIPEP","Gene synonym":["MIP"],"Ensembl":"ENSG00000027001","Gene description":"Mitochondrial intermediate peptidase","Uniprot":["Q99797"],"Chromosome":"13","Position":"23730189-23889400","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"108.0","Oligodendrocytes":"62.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"OE19":"64.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030676","HPA031669","HPA031670"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA030676":"AB_10598907","HPA031669":"AB_10600986","HPA031670":"AB_10602198"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.66e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.90e-3"},"Tissue RNA - adipose tissue [nTPM]":"6.3","Tissue RNA - adrenal gland [nTPM]":"9.6","Tissue RNA - amygdala [nTPM]":"3.7","Tissue RNA - appendix [nTPM]":"6.2","Tissue RNA - basal ganglia [nTPM]":"4.3","Tissue RNA - bone marrow [nTPM]":"5.3","Tissue RNA - breast [nTPM]":"11.1","Tissue RNA - cerebellum [nTPM]":"3.2","Tissue RNA - cerebral cortex [nTPM]":"5.0","Tissue RNA - cervix [nTPM]":"7.5","Tissue RNA - choroid plexus [nTPM]":"13.4","Tissue RNA - colon [nTPM]":"12.9","Tissue RNA - duodenum [nTPM]":"8.8","Tissue RNA - endometrium 1 [nTPM]":"7.2","Tissue RNA - epididymis [nTPM]":"12.4","Tissue RNA - esophagus [nTPM]":"11.5","Tissue RNA - fallopian tube [nTPM]":"17.3","Tissue RNA - gallbladder [nTPM]":"7.7","Tissue RNA - heart muscle [nTPM]":"18.4","Tissue RNA - hippocampal formation [nTPM]":"14.4","Tissue RNA - hypothalamus [nTPM]":"4.0","Tissue RNA - kidney [nTPM]":"25.4","Tissue RNA - liver [nTPM]":"12.0","Tissue RNA - lung [nTPM]":"7.1","Tissue RNA - lymph node [nTPM]":"5.1","Tissue RNA - medulla oblongata [nTPM]":"4.0","Tissue RNA - midbrain [nTPM]":"5.0","Tissue RNA - ovary [nTPM]":"5.4","Tissue RNA - pancreas [nTPM]":"8.2","Tissue RNA - parathyroid gland [nTPM]":"14.6","Tissue RNA - pituitary gland [nTPM]":"5.4","Tissue RNA - placenta [nTPM]":"4.7","Tissue RNA - pons [nTPM]":"4.6","Tissue RNA - prostate [nTPM]":"10.9","Tissue RNA - rectum [nTPM]":"13.1","Tissue RNA - retina [nTPM]":"6.1","Tissue RNA - salivary gland [nTPM]":"9.7","Tissue RNA - seminal vesicle [nTPM]":"8.7","Tissue RNA - skeletal muscle [nTPM]":"13.9","Tissue RNA - skin 1 [nTPM]":"21.4","Tissue RNA - small intestine [nTPM]":"7.6","Tissue RNA - smooth muscle [nTPM]":"7.8","Tissue RNA - spinal cord [nTPM]":"4.0","Tissue RNA - spleen [nTPM]":"4.3","Tissue RNA - stomach 1 [nTPM]":"8.6","Tissue RNA - testis [nTPM]":"9.8","Tissue RNA - thalamus [nTPM]":"3.7","Tissue RNA - thymus [nTPM]":"6.0","Tissue RNA - thyroid gland [nTPM]":"11.1","Tissue RNA - tongue [nTPM]":"16.9","Tissue RNA - tonsil [nTPM]":"7.8","Tissue RNA - urinary bladder [nTPM]":"7.7","Tissue RNA - vagina [nTPM]":"6.4","Tissue RNA - white matter [nTPM]":"4.9","Cell RNA - A-431 [nTPM]":"14.6","Cell RNA - A549 [nTPM]":"16.1","Cell RNA - AF22 [nTPM]":"7.8","Cell RNA - AN3-CA [nTPM]":"18.4","Cell RNA - ASC diff [nTPM]":"17.4","Cell RNA - ASC TERT1 [nTPM]":"23.4","Cell RNA - BEWO [nTPM]":"16.6","Cell RNA - BJ [nTPM]":"10.3","Cell RNA - BJ hTERT+ [nTPM]":"16.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.7","Cell RNA - CACO-2 [nTPM]":"21.7","Cell RNA - CAPAN-2 [nTPM]":"28.1","Cell RNA - Daudi [nTPM]":"17.0","Cell RNA - EFO-21 [nTPM]":"10.2","Cell RNA - fHDF\/TERT166 [nTPM]":"8.4","Cell RNA - GAMG [nTPM]":"13.3","Cell RNA - HaCaT [nTPM]":"35.8","Cell RNA - HAP1 [nTPM]":"18.1","Cell RNA - HBEC3-KT [nTPM]":"21.6","Cell RNA - HBF TERT88 [nTPM]":"18.8","Cell RNA - HDLM-2 [nTPM]":"9.9","Cell RNA - HEK 293 [nTPM]":"11.5","Cell RNA - HEL [nTPM]":"7.4","Cell RNA - HeLa [nTPM]":"7.0","Cell RNA - Hep G2 [nTPM]":"18.8","Cell RNA - HHSteC [nTPM]":"14.3","Cell RNA - HL-60 [nTPM]":"17.5","Cell RNA - HMC-1 [nTPM]":"3.9","Cell RNA - HSkMC [nTPM]":"11.6","Cell RNA - hTCEpi [nTPM]":"26.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.7","Cell RNA - hTERT-HME1 [nTPM]":"13.9","Cell RNA - hTERT-RPE1 [nTPM]":"12.7","Cell RNA - HUVEC TERT2 [nTPM]":"19.2","Cell RNA - JURKAT [nTPM]":"12.7","Cell RNA - K-562 [nTPM]":"14.5","Cell RNA - Karpas-707 [nTPM]":"2.7","Cell RNA - LHCN-M2 [nTPM]":"24.0","Cell RNA - MCF7 [nTPM]":"10.8","Cell RNA - MOLT-4 [nTPM]":"12.6","Cell RNA - NB-4 [nTPM]":"9.8","Cell RNA - NTERA-2 [nTPM]":"10.8","Cell RNA - OE19 [nTPM]":"64.8","Cell RNA - PC-3 [nTPM]":"16.1","Cell RNA - REH [nTPM]":"13.8","Cell RNA - RH-30 [nTPM]":"21.0","Cell RNA - RPMI-8226 [nTPM]":"14.8","Cell RNA - RPTEC TERT1 [nTPM]":"33.7","Cell RNA - RT4 [nTPM]":"9.6","Cell RNA - SCLC-21H [nTPM]":"18.2","Cell RNA - SH-SY5Y [nTPM]":"6.1","Cell RNA - SiHa [nTPM]":"11.0","Cell RNA - SK-BR-3 [nTPM]":"17.8","Cell RNA - SK-MEL-30 [nTPM]":"21.8","Cell RNA - SuSa [nTPM]":"9.8","Cell RNA - T-47d [nTPM]":"18.3","Cell RNA - THP-1 [nTPM]":"9.7","Cell RNA - TIME [nTPM]":"10.7","Cell RNA - U-138 MG [nTPM]":"9.2","Cell RNA - U-2 OS [nTPM]":"7.6","Cell RNA - U-2197 [nTPM]":"15.3","Cell RNA - U-251 MG [nTPM]":"11.2","Cell RNA - U-266\/70 [nTPM]":"2.6","Cell RNA - U-266\/84 [nTPM]":"4.0","Cell RNA - U-698 [nTPM]":"9.1","Cell RNA - U-87 MG [nTPM]":"15.9","Cell RNA - U-937 [nTPM]":"8.8","Cell RNA - WM-115 [nTPM]":"11.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"3.0","Blood RNA - eosinophil [nTPM]":"1.3","Blood RNA - gdT-cell [nTPM]":"7.4","Blood RNA - intermediate monocyte [nTPM]":"3.7","Blood RNA - MAIT T-cell [nTPM]":"9.3","Blood RNA - memory B-cell [nTPM]":"8.7","Blood RNA - memory CD4 T-cell [nTPM]":"7.1","Blood RNA - memory CD8 T-cell [nTPM]":"6.8","Blood RNA - myeloid DC [nTPM]":"6.5","Blood RNA - naive B-cell [nTPM]":"7.2","Blood RNA - naive CD4 T-cell [nTPM]":"6.7","Blood RNA - naive CD8 T-cell [nTPM]":"6.7","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"10.3","Blood RNA - non-classical monocyte [nTPM]":"12.0","Blood RNA - plasmacytoid DC [nTPM]":"5.5","Blood RNA - T-reg [nTPM]":"5.2","Blood RNA - total PBMC [nTPM]":"4.0","Brain RNA - amygdala [nTPM]":"3.7","Brain RNA - basal ganglia [nTPM]":"4.3","Brain RNA - cerebellum [nTPM]":"3.2","Brain RNA - cerebral cortex [nTPM]":"5.0","Brain RNA - hippocampal formation [nTPM]":"14.4","Brain RNA - hypothalamus [nTPM]":"4.0","Brain RNA - medulla oblongata [nTPM]":"4.0","Brain RNA - midbrain [nTPM]":"5.0","Brain RNA - pons [nTPM]":"4.6","Brain RNA - spinal cord [nTPM]":"4.0","Brain RNA - thalamus [nTPM]":"3.7","Brain RNA - white matter [nTPM]":"4.9","Single Cell Type RNA - Adipocytes [nTPM]":"2.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.6","Single Cell Type RNA - Astrocytes [nTPM]":"18.9","Single Cell Type RNA - B-cells [nTPM]":"5.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"39.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"3.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"108.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"12.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.8","Single Cell Type RNA - dendritic cells [nTPM]":"2.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"29.4","Single Cell Type RNA - Ductal cells [nTPM]":"23.4","Single Cell Type RNA - Early spermatids [nTPM]":"8.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"26.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.5","Single Cell Type RNA - Endothelial cells [nTPM]":"5.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"4.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"43.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.3","Single Cell Type RNA - Fibroblasts [nTPM]":"8.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.5","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"4.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"5.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.7","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"47.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.1","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"3.5","Single Cell Type RNA - Langerhans cells [nTPM]":"5.0","Single Cell Type RNA - Late spermatids [nTPM]":"7.4","Single Cell Type RNA - Leydig cells [nTPM]":"6.8","Single Cell Type RNA - Macrophages [nTPM]":"4.3","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"3.4","Single Cell Type RNA - Muller glia cells [nTPM]":"5.5","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"62.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.6","Single Cell Type RNA - Paneth cells [nTPM]":"7.0","Single Cell Type RNA - Peritubular cells [nTPM]":"8.6","Single Cell Type RNA - Plasma cells [nTPM]":"4.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"25.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"46.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.7","Single Cell Type RNA - Spermatocytes [nTPM]":"9.7","Single Cell Type RNA - Spermatogonia [nTPM]":"19.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"42.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.1","Single Cell Type RNA - T-cells [nTPM]":"4.0","Single Cell Type RNA - Theca cells [nTPM]":"8.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.6","Single Cell Type RNA - Urothelial cells [nTPM]":"5.6"},{"Gene":"MKRN3","Gene synonym":["D15S9","MGC88288","RNF63","ZFP127","ZNF127"],"Ensembl":"ENSG00000179455","Gene description":"Makorin ring finger protein 3","Uniprot":["Q13064"],"Chromosome":"15","Position":"23565674-23630075","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"14.1","retina":"8.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"13.8","Cone photoreceptor cells":"25.0","Horizontal cells":"6.7","Oligodendrocyte precursor cells":"6.0","Oligodendrocytes":"9.0","Rod photoreceptor cells":"7.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD8 T-cell":"2.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"JURKAT":"26.3","K-562":"30.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029494"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA029494":"AB_10603873"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.78e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"4.5","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"7.7","Tissue RNA - bone marrow [nTPM]":"1.8","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"4.8","Tissue RNA - cerebral cortex [nTPM]":"6.7","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"2.4","Tissue RNA - colon [nTPM]":"0.5","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"1.6","Tissue RNA - esophagus [nTPM]":"3.4","Tissue RNA - fallopian tube [nTPM]":"3.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"5.2","Tissue RNA - hypothalamus [nTPM]":"5.1","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.7","Tissue RNA - medulla oblongata [nTPM]":"7.0","Tissue RNA - midbrain [nTPM]":"6.1","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.1","Tissue RNA - placenta [nTPM]":"3.3","Tissue RNA - pons [nTPM]":"7.0","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"8.9","Tissue RNA - salivary gland [nTPM]":"3.1","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.8","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"4.0","Tissue RNA - spleen [nTPM]":"0.6","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"2.4","Tissue RNA - thalamus [nTPM]":"6.6","Tissue RNA - thymus [nTPM]":"2.4","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.8","Tissue RNA - tonsil [nTPM]":"0.8","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"14.1","Cell RNA - A-431 [nTPM]":"8.5","Cell RNA - A549 [nTPM]":"2.9","Cell RNA - AF22 [nTPM]":"6.1","Cell RNA - AN3-CA [nTPM]":"5.6","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"13.0","Cell RNA - BJ [nTPM]":"0.9","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.5","Cell RNA - CACO-2 [nTPM]":"14.7","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"11.8","Cell RNA - HaCaT [nTPM]":"12.5","Cell RNA - HAP1 [nTPM]":"2.4","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"2.7","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"15.3","Cell RNA - HeLa [nTPM]":"17.0","Cell RNA - Hep G2 [nTPM]":"0.9","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"18.6","Cell RNA - HMC-1 [nTPM]":"10.2","Cell RNA - HSkMC [nTPM]":"0.6","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.8","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"2.8","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"26.3","Cell RNA - K-562 [nTPM]":"30.6","Cell RNA - Karpas-707 [nTPM]":"12.9","Cell RNA - LHCN-M2 [nTPM]":"3.5","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"20.3","Cell RNA - NB-4 [nTPM]":"7.3","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"9.6","Cell RNA - PC-3 [nTPM]":"12.1","Cell RNA - REH [nTPM]":"10.7","Cell RNA - RH-30 [nTPM]":"2.5","Cell RNA - RPMI-8226 [nTPM]":"7.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"1.6","Cell RNA - SH-SY5Y [nTPM]":"4.4","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"7.7","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"4.2","Cell RNA - THP-1 [nTPM]":"5.2","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"13.5","Cell RNA - U-2 OS [nTPM]":"9.9","Cell RNA - U-2197 [nTPM]":"0.9","Cell RNA - U-251 MG [nTPM]":"9.6","Cell RNA - U-266\/70 [nTPM]":"16.8","Cell RNA - U-266\/84 [nTPM]":"24.5","Cell RNA - U-698 [nTPM]":"8.6","Cell RNA - U-87 MG [nTPM]":"7.9","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"2.3","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"4.5","Brain RNA - basal ganglia [nTPM]":"7.7","Brain RNA - cerebellum [nTPM]":"4.8","Brain RNA - cerebral cortex [nTPM]":"6.7","Brain RNA - hippocampal formation [nTPM]":"5.2","Brain RNA - hypothalamus [nTPM]":"5.1","Brain RNA - medulla oblongata [nTPM]":"7.0","Brain RNA - midbrain [nTPM]":"6.1","Brain RNA - pons [nTPM]":"7.0","Brain RNA - spinal cord [nTPM]":"4.0","Brain RNA - thalamus [nTPM]":"6.6","Brain RNA - white matter [nTPM]":"14.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"13.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"3.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.6","Single Cell Type RNA - Spermatocytes [nTPM]":"2.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"MLC1","Gene synonym":["KIAA0027","LVM","MLC","VL"],"Ensembl":"ENSG00000100427","Gene description":"Modulator of VRAC current 1","Uniprot":["Q15049"],"Chromosome":"22","Position":"50059391-50085426","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"262.7","choroid plexus":"145.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Astrocytes":"115.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"69","RNA cancer specific FPKM":{"glioma":"122.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"20.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HL-60":"228.2","NB-4":"219.8","THP-1":"401.5","U-266\/70":"131.6","U-266\/84":"120.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003040"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA003040":"AB_1079387"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-6"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"239.3","Tissue RNA - appendix [nTPM]":"0.7","Tissue RNA - basal ganglia [nTPM]":"235.7","Tissue RNA - bone marrow [nTPM]":"36.4","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"212.7","Tissue RNA - cerebral cortex [nTPM]":"261.8","Tissue RNA - cervix [nTPM]":"3.0","Tissue RNA - choroid plexus [nTPM]":"145.6","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"1.8","Tissue RNA - gallbladder [nTPM]":"1.0","Tissue RNA - heart muscle [nTPM]":"0.6","Tissue RNA - hippocampal formation [nTPM]":"225.8","Tissue RNA - hypothalamus [nTPM]":"234.5","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"1.6","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"262.7","Tissue RNA - midbrain [nTPM]":"243.1","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.1","Tissue RNA - placenta [nTPM]":"2.3","Tissue RNA - pons [nTPM]":"221.8","Tissue RNA - prostate [nTPM]":"4.8","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"4.1","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"1.4","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"1.0","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"231.9","Tissue RNA - spleen [nTPM]":"2.2","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"3.8","Tissue RNA - thalamus [nTPM]":"231.5","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"11.9","Tissue RNA - white matter [nTPM]":"217.2","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"2.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"68.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"228.2","Cell RNA - HMC-1 [nTPM]":"68.4","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"1.8","Cell RNA - NB-4 [nTPM]":"219.8","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"24.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"401.5","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"131.6","Cell RNA - U-266\/84 [nTPM]":"120.2","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"35.7","Cell RNA - WM-115 [nTPM]":"2.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"3.9","Blood RNA - intermediate monocyte [nTPM]":"6.8","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"1.6","Blood RNA - myeloid DC [nTPM]":"0.9","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"1.8","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"20.2","Blood RNA - non-classical monocyte [nTPM]":"9.2","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"4.0","Brain RNA - amygdala [nTPM]":"239.3","Brain RNA - basal ganglia [nTPM]":"235.7","Brain RNA - cerebellum [nTPM]":"212.7","Brain RNA - cerebral cortex [nTPM]":"261.8","Brain RNA - hippocampal formation [nTPM]":"225.8","Brain RNA - hypothalamus [nTPM]":"234.5","Brain RNA - medulla oblongata [nTPM]":"262.7","Brain RNA - midbrain [nTPM]":"243.1","Brain RNA - pons [nTPM]":"221.8","Brain RNA - spinal cord [nTPM]":"231.9","Brain RNA - thalamus [nTPM]":"231.5","Brain RNA - white matter [nTPM]":"217.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"115.6","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"17.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"7.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"2.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"4.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"16.3","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"2.7","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"MLYCD","Gene synonym":["hMCD","MCD"],"Ensembl":"ENSG00000103150","Gene description":"Malonyl-CoA decarboxylase","Uniprot":["O95822"],"Chromosome":"16","Position":"83899115-83951445","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Decarboxylase","Lyase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"tongue":"21.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"97.5","Cone photoreceptor cells":"125.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031625"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031625":"AB_10602028"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.61e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-3"},"Tissue RNA - adipose tissue [nTPM]":"2.5","Tissue RNA - adrenal gland [nTPM]":"2.1","Tissue RNA - amygdala [nTPM]":"1.9","Tissue RNA - appendix [nTPM]":"1.0","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"1.4","Tissue RNA - cerebellum [nTPM]":"1.5","Tissue RNA - cerebral cortex [nTPM]":"2.4","Tissue RNA - cervix [nTPM]":"1.1","Tissue RNA - choroid plexus [nTPM]":"2.7","Tissue RNA - colon [nTPM]":"1.7","Tissue RNA - duodenum [nTPM]":"1.7","Tissue RNA - endometrium 1 [nTPM]":"1.3","Tissue RNA - epididymis [nTPM]":"1.2","Tissue RNA - esophagus [nTPM]":"1.0","Tissue RNA - fallopian tube [nTPM]":"1.4","Tissue RNA - gallbladder [nTPM]":"0.7","Tissue RNA - heart muscle [nTPM]":"9.5","Tissue RNA - hippocampal formation [nTPM]":"1.7","Tissue RNA - hypothalamus [nTPM]":"1.9","Tissue RNA - kidney [nTPM]":"2.7","Tissue RNA - liver [nTPM]":"5.7","Tissue RNA - lung [nTPM]":"1.2","Tissue RNA - lymph node [nTPM]":"1.2","Tissue RNA - medulla oblongata [nTPM]":"2.5","Tissue RNA - midbrain [nTPM]":"2.5","Tissue RNA - ovary [nTPM]":"1.9","Tissue RNA - pancreas [nTPM]":"5.1","Tissue RNA - parathyroid gland [nTPM]":"2.0","Tissue RNA - pituitary gland [nTPM]":"1.2","Tissue RNA - placenta [nTPM]":"0.9","Tissue RNA - pons [nTPM]":"2.0","Tissue RNA - prostate [nTPM]":"1.2","Tissue RNA - rectum [nTPM]":"1.7","Tissue RNA - retina [nTPM]":"2.4","Tissue RNA - salivary gland [nTPM]":"2.1","Tissue RNA - seminal vesicle [nTPM]":"1.5","Tissue RNA - skeletal muscle [nTPM]":"8.2","Tissue RNA - skin 1 [nTPM]":"1.0","Tissue RNA - small intestine [nTPM]":"1.4","Tissue RNA - smooth muscle [nTPM]":"1.2","Tissue RNA - spinal cord [nTPM]":"1.6","Tissue RNA - spleen [nTPM]":"1.0","Tissue RNA - stomach 1 [nTPM]":"2.5","Tissue RNA - testis [nTPM]":"1.3","Tissue RNA - thalamus [nTPM]":"3.2","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"1.5","Tissue RNA - tongue [nTPM]":"21.5","Tissue RNA - tonsil [nTPM]":"0.9","Tissue RNA - urinary bladder [nTPM]":"1.6","Tissue RNA - vagina [nTPM]":"0.9","Tissue RNA - white matter [nTPM]":"2.5","Cell RNA - A-431 [nTPM]":"0.6","Cell RNA - A549 [nTPM]":"1.9","Cell RNA - AF22 [nTPM]":"1.6","Cell RNA - AN3-CA [nTPM]":"1.9","Cell RNA - ASC diff [nTPM]":"2.5","Cell RNA - ASC TERT1 [nTPM]":"0.9","Cell RNA - BEWO [nTPM]":"2.9","Cell RNA - BJ [nTPM]":"0.8","Cell RNA - BJ hTERT+ [nTPM]":"1.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"0.9","Cell RNA - CAPAN-2 [nTPM]":"1.5","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"2.4","Cell RNA - fHDF\/TERT166 [nTPM]":"1.2","Cell RNA - GAMG [nTPM]":"2.6","Cell RNA - HaCaT [nTPM]":"1.5","Cell RNA - HAP1 [nTPM]":"1.4","Cell RNA - HBEC3-KT [nTPM]":"0.6","Cell RNA - HBF TERT88 [nTPM]":"0.7","Cell RNA - HDLM-2 [nTPM]":"0.8","Cell RNA - HEK 293 [nTPM]":"1.9","Cell RNA - HEL [nTPM]":"0.9","Cell RNA - HeLa [nTPM]":"0.8","Cell RNA - Hep G2 [nTPM]":"1.9","Cell RNA - HHSteC [nTPM]":"3.0","Cell RNA - HL-60 [nTPM]":"1.2","Cell RNA - HMC-1 [nTPM]":"2.1","Cell RNA - HSkMC [nTPM]":"1.1","Cell RNA - hTCEpi [nTPM]":"1.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.4","Cell RNA - hTERT-HME1 [nTPM]":"0.4","Cell RNA - hTERT-RPE1 [nTPM]":"1.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.8","Cell RNA - JURKAT [nTPM]":"1.4","Cell RNA - K-562 [nTPM]":"1.4","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"1.1","Cell RNA - MCF7 [nTPM]":"2.4","Cell RNA - MOLT-4 [nTPM]":"0.7","Cell RNA - NB-4 [nTPM]":"2.7","Cell RNA - NTERA-2 [nTPM]":"1.6","Cell RNA - OE19 [nTPM]":"2.7","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"2.2","Cell RNA - RH-30 [nTPM]":"1.1","Cell RNA - RPMI-8226 [nTPM]":"1.1","Cell RNA - RPTEC TERT1 [nTPM]":"1.6","Cell RNA - RT4 [nTPM]":"1.1","Cell RNA - SCLC-21H [nTPM]":"1.4","Cell RNA - SH-SY5Y [nTPM]":"0.9","Cell RNA - SiHa [nTPM]":"3.0","Cell RNA - SK-BR-3 [nTPM]":"1.1","Cell RNA - SK-MEL-30 [nTPM]":"2.4","Cell RNA - SuSa [nTPM]":"2.1","Cell RNA - T-47d [nTPM]":"3.4","Cell RNA - THP-1 [nTPM]":"2.5","Cell RNA - TIME [nTPM]":"0.6","Cell RNA - U-138 MG [nTPM]":"1.8","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"1.0","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"2.1","Cell RNA - U-266\/84 [nTPM]":"1.3","Cell RNA - U-698 [nTPM]":"2.0","Cell RNA - U-87 MG [nTPM]":"1.0","Cell RNA - U-937 [nTPM]":"0.9","Cell RNA - WM-115 [nTPM]":"1.9","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.9","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"1.5","Brain RNA - cerebral cortex [nTPM]":"2.4","Brain RNA - hippocampal formation [nTPM]":"1.7","Brain RNA - hypothalamus [nTPM]":"1.9","Brain RNA - medulla oblongata [nTPM]":"2.5","Brain RNA - midbrain [nTPM]":"2.5","Brain RNA - pons [nTPM]":"2.0","Brain RNA - spinal cord [nTPM]":"1.6","Brain RNA - thalamus [nTPM]":"3.2","Brain RNA - white matter [nTPM]":"2.5","Single Cell Type RNA - Adipocytes [nTPM]":"6.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.3","Single Cell Type RNA - Astrocytes [nTPM]":"8.5","Single Cell Type RNA - B-cells [nTPM]":"10.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"25.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"97.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"5.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"125.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.2","Single Cell Type RNA - dendritic cells [nTPM]":"10.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"31.3","Single Cell Type RNA - Ductal cells [nTPM]":"5.7","Single Cell Type RNA - Early spermatids [nTPM]":"4.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.9","Single Cell Type RNA - Endothelial cells [nTPM]":"8.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.2","Single Cell Type RNA - Erythroid cells [nTPM]":"9.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.1","Single Cell Type RNA - Fibroblasts [nTPM]":"10.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.7","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"20.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.8","Single Cell Type RNA - Hepatocytes [nTPM]":"46.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.3","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.2","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"10.1","Single Cell Type RNA - Langerhans cells [nTPM]":"2.0","Single Cell Type RNA - Late spermatids [nTPM]":"8.6","Single Cell Type RNA - Leydig cells [nTPM]":"14.6","Single Cell Type RNA - Macrophages [nTPM]":"8.2","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"7.7","Single Cell Type RNA - Muller glia cells [nTPM]":"14.7","Single Cell Type RNA - NK-cells [nTPM]":"27.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.7","Single Cell Type RNA - Paneth cells [nTPM]":"13.1","Single Cell Type RNA - Peritubular cells [nTPM]":"19.5","Single Cell Type RNA - Plasma cells [nTPM]":"6.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"19.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"53.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.1","Single Cell Type RNA - Spermatocytes [nTPM]":"12.1","Single Cell Type RNA - Spermatogonia [nTPM]":"14.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.2","Single Cell Type RNA - T-cells [nTPM]":"9.0","Single Cell Type RNA - Theca cells [nTPM]":"17.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.1","Single Cell Type RNA - Urothelial cells [nTPM]":"8.6"},{"Gene":"MMAB","Gene synonym":["cblB","CFAP23"],"Ensembl":"ENSG00000139428","Gene description":"Metabolism of cobalamin associated B","Uniprot":["Q96EY8"],"Chromosome":"12","Position":"109553715-109573580","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"103.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"225.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039017"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA039017":"AB_10673603"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.55e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.5","Tissue RNA - adrenal gland [nTPM]":"51.2","Tissue RNA - amygdala [nTPM]":"17.8","Tissue RNA - appendix [nTPM]":"6.3","Tissue RNA - basal ganglia [nTPM]":"18.3","Tissue RNA - bone marrow [nTPM]":"5.8","Tissue RNA - breast [nTPM]":"15.8","Tissue RNA - cerebellum [nTPM]":"18.8","Tissue RNA - cerebral cortex [nTPM]":"26.9","Tissue RNA - cervix [nTPM]":"12.4","Tissue RNA - choroid plexus [nTPM]":"18.6","Tissue RNA - colon [nTPM]":"15.8","Tissue RNA - duodenum [nTPM]":"13.0","Tissue RNA - endometrium 1 [nTPM]":"10.7","Tissue RNA - epididymis [nTPM]":"21.2","Tissue RNA - esophagus [nTPM]":"29.1","Tissue RNA - fallopian tube [nTPM]":"13.0","Tissue RNA - gallbladder [nTPM]":"6.0","Tissue RNA - heart muscle [nTPM]":"30.0","Tissue RNA - hippocampal formation [nTPM]":"17.0","Tissue RNA - hypothalamus [nTPM]":"18.8","Tissue RNA - kidney [nTPM]":"32.8","Tissue RNA - liver [nTPM]":"103.6","Tissue RNA - lung [nTPM]":"14.9","Tissue RNA - lymph node [nTPM]":"6.2","Tissue RNA - medulla oblongata [nTPM]":"22.2","Tissue RNA - midbrain [nTPM]":"19.0","Tissue RNA - ovary [nTPM]":"18.9","Tissue RNA - pancreas [nTPM]":"23.0","Tissue RNA - parathyroid gland [nTPM]":"9.8","Tissue RNA - pituitary gland [nTPM]":"20.5","Tissue RNA - placenta [nTPM]":"4.9","Tissue RNA - pons [nTPM]":"21.3","Tissue RNA - prostate [nTPM]":"26.5","Tissue RNA - rectum [nTPM]":"7.9","Tissue RNA - retina [nTPM]":"7.3","Tissue RNA - salivary gland [nTPM]":"17.1","Tissue RNA - seminal vesicle [nTPM]":"6.3","Tissue RNA - skeletal muscle [nTPM]":"21.1","Tissue RNA - skin 1 [nTPM]":"18.2","Tissue RNA - small intestine [nTPM]":"14.0","Tissue RNA - smooth muscle [nTPM]":"5.6","Tissue RNA - spinal cord [nTPM]":"19.0","Tissue RNA - spleen [nTPM]":"12.4","Tissue RNA - stomach 1 [nTPM]":"17.7","Tissue RNA - testis [nTPM]":"12.6","Tissue RNA - thalamus [nTPM]":"18.9","Tissue RNA - thymus [nTPM]":"5.5","Tissue RNA - thyroid gland [nTPM]":"22.1","Tissue RNA - tongue [nTPM]":"16.2","Tissue RNA - tonsil [nTPM]":"6.5","Tissue RNA - urinary bladder [nTPM]":"14.1","Tissue RNA - vagina [nTPM]":"14.7","Tissue RNA - white matter [nTPM]":"22.9","Cell RNA - A-431 [nTPM]":"32.2","Cell RNA - A549 [nTPM]":"22.3","Cell RNA - AF22 [nTPM]":"22.2","Cell RNA - AN3-CA [nTPM]":"17.6","Cell RNA - ASC diff [nTPM]":"8.8","Cell RNA - ASC TERT1 [nTPM]":"17.7","Cell RNA - BEWO [nTPM]":"11.3","Cell RNA - BJ [nTPM]":"7.1","Cell RNA - BJ hTERT+ [nTPM]":"16.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.8","Cell RNA - CACO-2 [nTPM]":"25.8","Cell RNA - CAPAN-2 [nTPM]":"29.5","Cell RNA - Daudi [nTPM]":"21.0","Cell RNA - EFO-21 [nTPM]":"19.9","Cell RNA - fHDF\/TERT166 [nTPM]":"8.0","Cell RNA - GAMG [nTPM]":"19.1","Cell RNA - HaCaT [nTPM]":"32.9","Cell RNA - HAP1 [nTPM]":"14.6","Cell RNA - HBEC3-KT [nTPM]":"54.9","Cell RNA - HBF TERT88 [nTPM]":"4.6","Cell RNA - HDLM-2 [nTPM]":"8.2","Cell RNA - HEK 293 [nTPM]":"60.9","Cell RNA - HEL [nTPM]":"8.6","Cell RNA - HeLa [nTPM]":"15.9","Cell RNA - Hep G2 [nTPM]":"42.1","Cell RNA - HHSteC [nTPM]":"31.3","Cell RNA - HL-60 [nTPM]":"18.4","Cell RNA - HMC-1 [nTPM]":"7.2","Cell RNA - HSkMC [nTPM]":"24.0","Cell RNA - hTCEpi [nTPM]":"33.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.2","Cell RNA - hTERT-HME1 [nTPM]":"9.7","Cell RNA - hTERT-RPE1 [nTPM]":"12.3","Cell RNA - HUVEC TERT2 [nTPM]":"9.7","Cell RNA - JURKAT [nTPM]":"16.4","Cell RNA - K-562 [nTPM]":"27.5","Cell RNA - Karpas-707 [nTPM]":"15.5","Cell RNA - LHCN-M2 [nTPM]":"7.3","Cell RNA - MCF7 [nTPM]":"74.7","Cell RNA - MOLT-4 [nTPM]":"16.6","Cell RNA - NB-4 [nTPM]":"29.2","Cell RNA - NTERA-2 [nTPM]":"27.3","Cell RNA - OE19 [nTPM]":"3.3","Cell RNA - PC-3 [nTPM]":"31.6","Cell RNA - REH [nTPM]":"13.6","Cell RNA - RH-30 [nTPM]":"8.7","Cell RNA - RPMI-8226 [nTPM]":"53.9","Cell RNA - RPTEC TERT1 [nTPM]":"45.3","Cell RNA - RT4 [nTPM]":"30.3","Cell RNA - SCLC-21H [nTPM]":"34.1","Cell RNA - SH-SY5Y [nTPM]":"14.8","Cell RNA - SiHa [nTPM]":"15.8","Cell RNA - SK-BR-3 [nTPM]":"29.2","Cell RNA - SK-MEL-30 [nTPM]":"12.7","Cell RNA - SuSa [nTPM]":"6.2","Cell RNA - T-47d [nTPM]":"60.5","Cell RNA - THP-1 [nTPM]":"50.5","Cell RNA - TIME [nTPM]":"5.4","Cell RNA - U-138 MG [nTPM]":"8.6","Cell RNA - U-2 OS [nTPM]":"3.6","Cell RNA - U-2197 [nTPM]":"6.1","Cell RNA - U-251 MG [nTPM]":"10.4","Cell RNA - U-266\/70 [nTPM]":"11.9","Cell RNA - U-266\/84 [nTPM]":"9.6","Cell RNA - U-698 [nTPM]":"24.0","Cell RNA - U-87 MG [nTPM]":"19.0","Cell RNA - U-937 [nTPM]":"22.2","Cell RNA - WM-115 [nTPM]":"23.9","Blood RNA - basophil [nTPM]":"7.4","Blood RNA - classical monocyte [nTPM]":"7.2","Blood RNA - eosinophil [nTPM]":"1.0","Blood RNA - gdT-cell [nTPM]":"15.3","Blood RNA - intermediate monocyte [nTPM]":"10.0","Blood RNA - MAIT T-cell [nTPM]":"12.2","Blood RNA - memory B-cell [nTPM]":"13.6","Blood RNA - memory CD4 T-cell [nTPM]":"11.1","Blood RNA - memory CD8 T-cell [nTPM]":"12.1","Blood RNA - myeloid DC [nTPM]":"11.3","Blood RNA - naive B-cell [nTPM]":"17.8","Blood RNA - naive CD4 T-cell [nTPM]":"15.2","Blood RNA - naive CD8 T-cell [nTPM]":"14.6","Blood RNA - neutrophil [nTPM]":"1.9","Blood RNA - NK-cell [nTPM]":"11.2","Blood RNA - non-classical monocyte [nTPM]":"10.9","Blood RNA - plasmacytoid DC [nTPM]":"9.2","Blood RNA - T-reg [nTPM]":"5.8","Blood RNA - total PBMC [nTPM]":"10.3","Brain RNA - amygdala [nTPM]":"17.8","Brain RNA - basal ganglia [nTPM]":"18.3","Brain RNA - cerebellum [nTPM]":"18.8","Brain RNA - cerebral cortex [nTPM]":"26.9","Brain RNA - hippocampal formation [nTPM]":"17.0","Brain RNA - hypothalamus [nTPM]":"18.8","Brain RNA - medulla oblongata [nTPM]":"22.2","Brain RNA - midbrain [nTPM]":"19.0","Brain RNA - pons [nTPM]":"21.3","Brain RNA - spinal cord [nTPM]":"19.0","Brain RNA - thalamus [nTPM]":"18.9","Brain RNA - white matter [nTPM]":"22.9","Single Cell Type RNA - Adipocytes [nTPM]":"25.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"80.8","Single Cell Type RNA - Astrocytes [nTPM]":"9.8","Single Cell Type RNA - B-cells [nTPM]":"20.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"33.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"105.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Bipolar cells [nTPM]":"32.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"59.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"47.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"52.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"60.1","Single Cell Type RNA - Club cells [nTPM]":"68.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"42.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"55.4","Single Cell Type RNA - dendritic cells [nTPM]":"15.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"33.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"150.6","Single Cell Type RNA - Ductal cells [nTPM]":"49.7","Single Cell Type RNA - Early spermatids [nTPM]":"41.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.0","Single Cell Type RNA - Endothelial cells [nTPM]":"22.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"33.0","Single Cell Type RNA - Erythroid cells [nTPM]":"34.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"71.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"37.6","Single Cell Type RNA - Fibroblasts [nTPM]":"24.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"28.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.5","Single Cell Type RNA - granulocytes [nTPM]":"16.5","Single Cell Type RNA - Granulosa cells [nTPM]":"34.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.5","Single Cell Type RNA - Hepatocytes [nTPM]":"225.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"34.8","Single Cell Type RNA - Horizontal cells [nTPM]":"104.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"50.4","Single Cell Type RNA - Ionocytes [nTPM]":"71.2","Single Cell Type RNA - Kupffer cells [nTPM]":"20.4","Single Cell Type RNA - Langerhans cells [nTPM]":"10.2","Single Cell Type RNA - Late spermatids [nTPM]":"82.9","Single Cell Type RNA - Leydig cells [nTPM]":"40.4","Single Cell Type RNA - Macrophages [nTPM]":"13.5","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"25.1","Single Cell Type RNA - Muller glia cells [nTPM]":"30.6","Single Cell Type RNA - NK-cells [nTPM]":"30.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.7","Single Cell Type RNA - Paneth cells [nTPM]":"30.0","Single Cell Type RNA - Peritubular cells [nTPM]":"30.5","Single Cell Type RNA - Plasma cells [nTPM]":"18.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"31.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"61.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"143.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"62.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"29.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.3","Single Cell Type RNA - Spermatocytes [nTPM]":"26.0","Single Cell Type RNA - Spermatogonia [nTPM]":"15.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"44.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"19.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"61.8","Single Cell Type RNA - T-cells [nTPM]":"16.1","Single Cell Type RNA - Theca cells [nTPM]":"121.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"56.6","Single Cell Type RNA - Urothelial cells [nTPM]":"30.3"},{"Gene":"MMACHC","Gene synonym":["cblC","DKFZP564I122"],"Ensembl":"ENSG00000132763","Gene description":"Metabolism of cobalamin associated C","Uniprot":["Q9Y4U1"],"Chromosome":"1","Position":"45500300-45513382","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"17.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"22.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027394","HPA027399","HPA027402"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Plasma membrane","Cytosol"],"Antibody RRID":{"HPA027394":"AB_10601669","HPA027399":"AB_10601987","HPA027402":"AB_2672255"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.0","Tissue RNA - adrenal gland [nTPM]":"3.1","Tissue RNA - amygdala [nTPM]":"3.3","Tissue RNA - appendix [nTPM]":"1.7","Tissue RNA - basal ganglia [nTPM]":"5.3","Tissue RNA - bone marrow [nTPM]":"1.2","Tissue RNA - breast [nTPM]":"3.5","Tissue RNA - cerebellum [nTPM]":"5.1","Tissue RNA - cerebral cortex [nTPM]":"4.2","Tissue RNA - cervix [nTPM]":"2.9","Tissue RNA - choroid plexus [nTPM]":"2.3","Tissue RNA - colon [nTPM]":"3.7","Tissue RNA - duodenum [nTPM]":"3.3","Tissue RNA - endometrium 1 [nTPM]":"1.7","Tissue RNA - epididymis [nTPM]":"3.0","Tissue RNA - esophagus [nTPM]":"2.8","Tissue RNA - fallopian tube [nTPM]":"3.5","Tissue RNA - gallbladder [nTPM]":"1.3","Tissue RNA - heart muscle [nTPM]":"6.9","Tissue RNA - hippocampal formation [nTPM]":"3.4","Tissue RNA - hypothalamus [nTPM]":"5.1","Tissue RNA - kidney [nTPM]":"3.5","Tissue RNA - liver [nTPM]":"17.4","Tissue RNA - lung [nTPM]":"1.2","Tissue RNA - lymph node [nTPM]":"1.8","Tissue RNA - medulla oblongata [nTPM]":"4.1","Tissue RNA - midbrain [nTPM]":"5.6","Tissue RNA - ovary [nTPM]":"3.5","Tissue RNA - pancreas [nTPM]":"2.9","Tissue RNA - parathyroid gland [nTPM]":"5.5","Tissue RNA - pituitary gland [nTPM]":"1.3","Tissue RNA - placenta [nTPM]":"1.5","Tissue RNA - pons [nTPM]":"3.9","Tissue RNA - prostate [nTPM]":"2.0","Tissue RNA - rectum [nTPM]":"4.4","Tissue RNA - retina [nTPM]":"2.1","Tissue RNA - salivary gland [nTPM]":"5.0","Tissue RNA - seminal vesicle [nTPM]":"2.4","Tissue RNA - skeletal muscle [nTPM]":"10.8","Tissue RNA - skin 1 [nTPM]":"2.0","Tissue RNA - small intestine [nTPM]":"2.4","Tissue RNA - smooth muscle [nTPM]":"2.3","Tissue RNA - spinal cord [nTPM]":"3.5","Tissue RNA - spleen [nTPM]":"1.6","Tissue RNA - stomach 1 [nTPM]":"2.3","Tissue RNA - testis [nTPM]":"4.3","Tissue RNA - thalamus [nTPM]":"5.6","Tissue RNA - thymus [nTPM]":"2.2","Tissue RNA - thyroid gland [nTPM]":"2.3","Tissue RNA - tongue [nTPM]":"6.6","Tissue RNA - tonsil [nTPM]":"2.0","Tissue RNA - urinary bladder [nTPM]":"1.7","Tissue RNA - vagina [nTPM]":"1.5","Tissue RNA - white matter [nTPM]":"6.0","Cell RNA - A-431 [nTPM]":"7.7","Cell RNA - A549 [nTPM]":"3.9","Cell RNA - AF22 [nTPM]":"6.6","Cell RNA - AN3-CA [nTPM]":"10.0","Cell RNA - ASC diff [nTPM]":"6.1","Cell RNA - ASC TERT1 [nTPM]":"3.7","Cell RNA - BEWO [nTPM]":"8.1","Cell RNA - BJ [nTPM]":"5.9","Cell RNA - BJ hTERT+ [nTPM]":"3.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.4","Cell RNA - CACO-2 [nTPM]":"8.3","Cell RNA - CAPAN-2 [nTPM]":"4.7","Cell RNA - Daudi [nTPM]":"12.0","Cell RNA - EFO-21 [nTPM]":"7.4","Cell RNA - fHDF\/TERT166 [nTPM]":"4.9","Cell RNA - GAMG [nTPM]":"2.0","Cell RNA - HaCaT [nTPM]":"6.2","Cell RNA - HAP1 [nTPM]":"12.3","Cell RNA - HBEC3-KT [nTPM]":"14.0","Cell RNA - HBF TERT88 [nTPM]":"9.6","Cell RNA - HDLM-2 [nTPM]":"3.3","Cell RNA - HEK 293 [nTPM]":"11.4","Cell RNA - HEL [nTPM]":"9.4","Cell RNA - HeLa [nTPM]":"6.5","Cell RNA - Hep G2 [nTPM]":"9.2","Cell RNA - HHSteC [nTPM]":"5.8","Cell RNA - HL-60 [nTPM]":"13.5","Cell RNA - HMC-1 [nTPM]":"3.3","Cell RNA - HSkMC [nTPM]":"5.3","Cell RNA - hTCEpi [nTPM]":"7.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.6","Cell RNA - hTERT-HME1 [nTPM]":"12.6","Cell RNA - hTERT-RPE1 [nTPM]":"3.7","Cell RNA - HUVEC TERT2 [nTPM]":"5.1","Cell RNA - JURKAT [nTPM]":"12.5","Cell RNA - K-562 [nTPM]":"10.8","Cell RNA - Karpas-707 [nTPM]":"6.7","Cell RNA - LHCN-M2 [nTPM]":"8.1","Cell RNA - MCF7 [nTPM]":"8.2","Cell RNA - MOLT-4 [nTPM]":"9.1","Cell RNA - NB-4 [nTPM]":"4.3","Cell RNA - NTERA-2 [nTPM]":"10.9","Cell RNA - OE19 [nTPM]":"8.8","Cell RNA - PC-3 [nTPM]":"8.9","Cell RNA - REH [nTPM]":"11.1","Cell RNA - RH-30 [nTPM]":"2.7","Cell RNA - RPMI-8226 [nTPM]":"13.2","Cell RNA - RPTEC TERT1 [nTPM]":"6.2","Cell RNA - RT4 [nTPM]":"6.0","Cell RNA - SCLC-21H [nTPM]":"10.5","Cell RNA - SH-SY5Y [nTPM]":"5.4","Cell RNA - SiHa [nTPM]":"8.8","Cell RNA - SK-BR-3 [nTPM]":"14.5","Cell RNA - SK-MEL-30 [nTPM]":"19.3","Cell RNA - SuSa [nTPM]":"4.9","Cell RNA - T-47d [nTPM]":"8.3","Cell RNA - THP-1 [nTPM]":"4.6","Cell RNA - TIME [nTPM]":"2.3","Cell RNA - U-138 MG [nTPM]":"7.3","Cell RNA - U-2 OS [nTPM]":"9.9","Cell RNA - U-2197 [nTPM]":"8.3","Cell RNA - U-251 MG [nTPM]":"3.3","Cell RNA - U-266\/70 [nTPM]":"9.9","Cell RNA - U-266\/84 [nTPM]":"8.5","Cell RNA - U-698 [nTPM]":"6.9","Cell RNA - U-87 MG [nTPM]":"5.3","Cell RNA - U-937 [nTPM]":"6.4","Cell RNA - WM-115 [nTPM]":"6.9","Blood RNA - basophil [nTPM]":"2.3","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.7","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"2.7","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"3.3","Brain RNA - basal ganglia [nTPM]":"5.3","Brain RNA - cerebellum [nTPM]":"5.1","Brain RNA - cerebral cortex [nTPM]":"4.2","Brain RNA - hippocampal formation [nTPM]":"3.4","Brain RNA - hypothalamus [nTPM]":"5.1","Brain RNA - medulla oblongata [nTPM]":"4.1","Brain RNA - midbrain [nTPM]":"5.6","Brain RNA - pons [nTPM]":"3.9","Brain RNA - spinal cord [nTPM]":"3.5","Brain RNA - thalamus [nTPM]":"5.6","Brain RNA - white matter [nTPM]":"6.0","Single Cell Type RNA - Adipocytes [nTPM]":"1.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.5","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"2.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"1.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"2.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.7","Single Cell Type RNA - dendritic cells [nTPM]":"0.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.8","Single Cell Type RNA - Endothelial cells [nTPM]":"1.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"4.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.3","Single Cell Type RNA - Fibroblasts [nTPM]":"3.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.2","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"2.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"22.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.3","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.2","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.2","Single Cell Type RNA - Langerhans cells [nTPM]":"0.9","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"2.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"1.4","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.8","Single Cell Type RNA - Paneth cells [nTPM]":"2.3","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"10.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.4","Single Cell Type RNA - Spermatocytes [nTPM]":"7.4","Single Cell Type RNA - Spermatogonia [nTPM]":"2.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.7","Single Cell Type RNA - T-cells [nTPM]":"2.4","Single Cell Type RNA - Theca cells [nTPM]":"3.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.8","Single Cell Type RNA - Urothelial cells [nTPM]":"1.8"},{"Gene":"MMP13","Gene synonym":["CLG3"],"Ensembl":"ENSG00000137745","Gene description":"Matrix metallopeptidase 13","Uniprot":["P45452"],"Chromosome":"11","Position":"102942995-102955732","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted secreted proteins"],"Biological process":["Collagen degradation"],"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Cancer-related genes","Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"urinary bladder":"12.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Basal respiratory cells":"426.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"70.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"HaCaT":"17.9","PC-3":"6.7"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002742"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002742":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"12.9","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"17.9","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.5","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"6.7","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"1.8","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"2.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"2.4","Cell RNA - U-2 OS [nTPM]":"1.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"426.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"33.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"15.8"},{"Gene":"MMP14","Gene synonym":["MT1-MMP"],"Ensembl":"ENSG00000157227","Gene description":"Matrix metallopeptidase 14","Uniprot":["P50281"],"Chromosome":"14","Position":"22836560-22849041","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"244.0","Pancreatic endocrine cells":"144.7","Syncytiotrophoblasts":"122.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"923.8","HHSteC":"794.2","HSkMC":"887.0","hTERT-RPE1":"925.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009918","HPA051432"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Intermediate filaments","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1400000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":["Intermediate filaments"],"Antibody RRID":{"CAB009918":"AB_2250767","HPA051432":"AB_2681484"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.48e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.34e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-3"},"Tissue RNA - adipose tissue [nTPM]":"151.5","Tissue RNA - adrenal gland [nTPM]":"31.7","Tissue RNA - amygdala [nTPM]":"5.6","Tissue RNA - appendix [nTPM]":"59.9","Tissue RNA - basal ganglia [nTPM]":"5.0","Tissue RNA - bone marrow [nTPM]":"1.6","Tissue RNA - breast [nTPM]":"101.5","Tissue RNA - cerebellum [nTPM]":"5.7","Tissue RNA - cerebral cortex [nTPM]":"7.5","Tissue RNA - cervix [nTPM]":"181.3","Tissue RNA - choroid plexus [nTPM]":"61.8","Tissue RNA - colon [nTPM]":"77.2","Tissue RNA - duodenum [nTPM]":"39.5","Tissue RNA - endometrium 1 [nTPM]":"167.3","Tissue RNA - epididymis [nTPM]":"19.0","Tissue RNA - esophagus [nTPM]":"92.1","Tissue RNA - fallopian tube [nTPM]":"82.1","Tissue RNA - gallbladder [nTPM]":"148.2","Tissue RNA - heart muscle [nTPM]":"41.3","Tissue RNA - hippocampal formation [nTPM]":"6.6","Tissue RNA - hypothalamus [nTPM]":"7.2","Tissue RNA - kidney [nTPM]":"35.9","Tissue RNA - liver [nTPM]":"13.2","Tissue RNA - lung [nTPM]":"91.8","Tissue RNA - lymph node [nTPM]":"24.8","Tissue RNA - medulla oblongata [nTPM]":"11.9","Tissue RNA - midbrain [nTPM]":"8.4","Tissue RNA - ovary [nTPM]":"90.2","Tissue RNA - pancreas [nTPM]":"36.0","Tissue RNA - parathyroid gland [nTPM]":"65.3","Tissue RNA - pituitary gland [nTPM]":"14.2","Tissue RNA - placenta [nTPM]":"118.9","Tissue RNA - pons [nTPM]":"9.2","Tissue RNA - prostate [nTPM]":"59.9","Tissue RNA - rectum [nTPM]":"36.6","Tissue RNA - retina [nTPM]":"9.6","Tissue RNA - salivary gland [nTPM]":"78.1","Tissue RNA - seminal vesicle [nTPM]":"45.5","Tissue RNA - skeletal muscle [nTPM]":"18.8","Tissue RNA - skin 1 [nTPM]":"127.5","Tissue RNA - small intestine [nTPM]":"69.4","Tissue RNA - smooth muscle [nTPM]":"106.0","Tissue RNA - spinal cord [nTPM]":"7.3","Tissue RNA - spleen [nTPM]":"30.8","Tissue RNA - stomach 1 [nTPM]":"57.7","Tissue RNA - testis [nTPM]":"11.7","Tissue RNA - thalamus [nTPM]":"13.2","Tissue RNA - thymus [nTPM]":"13.0","Tissue RNA - thyroid gland [nTPM]":"50.0","Tissue RNA - tongue [nTPM]":"16.1","Tissue RNA - tonsil [nTPM]":"30.8","Tissue RNA - urinary bladder [nTPM]":"103.9","Tissue RNA - vagina [nTPM]":"111.1","Tissue RNA - white matter [nTPM]":"10.6","Cell RNA - A-431 [nTPM]":"90.6","Cell RNA - A549 [nTPM]":"1.2","Cell RNA - AF22 [nTPM]":"26.3","Cell RNA - AN3-CA [nTPM]":"2.0","Cell RNA - ASC diff [nTPM]":"923.8","Cell RNA - ASC TERT1 [nTPM]":"651.6","Cell RNA - BEWO [nTPM]":"455.9","Cell RNA - BJ [nTPM]":"270.1","Cell RNA - BJ hTERT+ [nTPM]":"606.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"93.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"158.5","Cell RNA - CACO-2 [nTPM]":"21.3","Cell RNA - CAPAN-2 [nTPM]":"337.4","Cell RNA - Daudi [nTPM]":"0.9","Cell RNA - EFO-21 [nTPM]":"146.4","Cell RNA - fHDF\/TERT166 [nTPM]":"301.9","Cell RNA - GAMG [nTPM]":"24.6","Cell RNA - HaCaT [nTPM]":"216.3","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"262.2","Cell RNA - HBF TERT88 [nTPM]":"99.7","Cell RNA - HDLM-2 [nTPM]":"1.1","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"37.2","Cell RNA - HeLa [nTPM]":"1.7","Cell RNA - Hep G2 [nTPM]":"5.0","Cell RNA - HHSteC [nTPM]":"794.2","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"1.3","Cell RNA - HSkMC [nTPM]":"887.0","Cell RNA - hTCEpi [nTPM]":"148.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"334.7","Cell RNA - hTERT-HME1 [nTPM]":"288.3","Cell RNA - hTERT-RPE1 [nTPM]":"925.5","Cell RNA - HUVEC TERT2 [nTPM]":"492.9","Cell RNA - JURKAT [nTPM]":"0.6","Cell RNA - K-562 [nTPM]":"0.8","Cell RNA - Karpas-707 [nTPM]":"2.1","Cell RNA - LHCN-M2 [nTPM]":"185.1","Cell RNA - MCF7 [nTPM]":"0.7","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"79.4","Cell RNA - NTERA-2 [nTPM]":"14.7","Cell RNA - OE19 [nTPM]":"17.7","Cell RNA - PC-3 [nTPM]":"52.4","Cell RNA - REH [nTPM]":"2.1","Cell RNA - RH-30 [nTPM]":"96.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"61.4","Cell RNA - RT4 [nTPM]":"148.1","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"0.6","Cell RNA - SiHa [nTPM]":"187.3","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"574.2","Cell RNA - SuSa [nTPM]":"104.4","Cell RNA - T-47d [nTPM]":"1.0","Cell RNA - THP-1 [nTPM]":"79.5","Cell RNA - TIME [nTPM]":"436.8","Cell RNA - U-138 MG [nTPM]":"724.9","Cell RNA - U-2 OS [nTPM]":"53.7","Cell RNA - U-2197 [nTPM]":"198.2","Cell RNA - U-251 MG [nTPM]":"329.6","Cell RNA - U-266\/70 [nTPM]":"0.8","Cell RNA - U-266\/84 [nTPM]":"1.6","Cell RNA - U-698 [nTPM]":"1.1","Cell RNA - U-87 MG [nTPM]":"410.9","Cell RNA - U-937 [nTPM]":"0.6","Cell RNA - WM-115 [nTPM]":"396.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"5.6","Brain RNA - basal ganglia [nTPM]":"5.0","Brain RNA - cerebellum [nTPM]":"5.7","Brain RNA - cerebral cortex [nTPM]":"7.5","Brain RNA - hippocampal formation [nTPM]":"6.6","Brain RNA - hypothalamus [nTPM]":"7.2","Brain RNA - medulla oblongata [nTPM]":"11.9","Brain RNA - midbrain [nTPM]":"8.4","Brain RNA - pons [nTPM]":"9.2","Brain RNA - spinal cord [nTPM]":"7.3","Brain RNA - thalamus [nTPM]":"13.2","Brain RNA - white matter [nTPM]":"10.6","Single Cell Type RNA - Adipocytes [nTPM]":"13.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"3.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"34.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"105.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"39.3","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"50.1","Single Cell Type RNA - Club cells [nTPM]":"42.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"105.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"19.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"63.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"81.6","Single Cell Type RNA - Endothelial cells [nTPM]":"35.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"28.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"244.0","Single Cell Type RNA - Fibroblasts [nTPM]":"84.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"25.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.8","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"9.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.9","Single Cell Type RNA - Hepatocytes [nTPM]":"2.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"89.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.5","Single Cell Type RNA - Ionocytes [nTPM]":"34.6","Single Cell Type RNA - Kupffer cells [nTPM]":"20.2","Single Cell Type RNA - Langerhans cells [nTPM]":"32.7","Single Cell Type RNA - Late spermatids [nTPM]":"2.4","Single Cell Type RNA - Leydig cells [nTPM]":"72.1","Single Cell Type RNA - Macrophages [nTPM]":"38.0","Single Cell Type RNA - Melanocytes [nTPM]":"37.4","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"21.5","Single Cell Type RNA - Muller glia cells [nTPM]":"14.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"144.7","Single Cell Type RNA - Paneth cells [nTPM]":"33.0","Single Cell Type RNA - Peritubular cells [nTPM]":"54.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"21.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"19.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"46.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"73.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"33.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"34.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"122.7","Single Cell Type RNA - T-cells [nTPM]":"2.5","Single Cell Type RNA - Theca cells [nTPM]":"15.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.6","Single Cell Type RNA - Urothelial cells [nTPM]":"37.9"},{"Gene":"MMP19","Gene synonym":["MMP18","RASI-1"],"Ensembl":"ENSG00000123342","Gene description":"Matrix metallopeptidase 19","Uniprot":["Q99542"],"Chromosome":"12","Position":"55835433-55842966","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted secreted proteins"],"Biological process":["Angiogenesis","Collagen degradation","Differentiation"],"Molecular function":["Developmental protein","Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"58.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"54.4","Fibroblasts":"52.8","Hofbauer cells":"30.8","Kupffer cells":"35.7","Langerhans cells":"100.7","Macrophages":"61.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"thalamus":"1.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"BEWO":"75.6"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"olfactory bulb":"7.2"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070804"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Vesicles"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2100000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Endoplasmic reticulum","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA070804":"AB_2686315"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.56e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Tissue RNA - adipose tissue [nTPM]":"58.5","Tissue RNA - adrenal gland [nTPM]":"3.6","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"11.4","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"18.3","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"10.4","Tissue RNA - choroid plexus [nTPM]":"0.5","Tissue RNA - colon [nTPM]":"7.3","Tissue RNA - duodenum [nTPM]":"1.2","Tissue RNA - endometrium 1 [nTPM]":"20.7","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"2.3","Tissue RNA - fallopian tube [nTPM]":"17.2","Tissue RNA - gallbladder [nTPM]":"25.6","Tissue RNA - heart muscle [nTPM]":"8.8","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"5.7","Tissue RNA - liver [nTPM]":"2.7","Tissue RNA - lung [nTPM]":"25.4","Tissue RNA - lymph node [nTPM]":"2.8","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"11.9","Tissue RNA - pancreas [nTPM]":"7.2","Tissue RNA - parathyroid gland [nTPM]":"0.5","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"10.8","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"3.3","Tissue RNA - rectum [nTPM]":"3.3","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"3.1","Tissue RNA - seminal vesicle [nTPM]":"2.3","Tissue RNA - skeletal muscle [nTPM]":"0.9","Tissue RNA - skin 1 [nTPM]":"5.5","Tissue RNA - small intestine [nTPM]":"8.7","Tissue RNA - smooth muscle [nTPM]":"8.7","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"27.4","Tissue RNA - stomach 1 [nTPM]":"9.6","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"1.3","Tissue RNA - thymus [nTPM]":"2.9","Tissue RNA - thyroid gland [nTPM]":"4.4","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"6.9","Tissue RNA - urinary bladder [nTPM]":"9.6","Tissue RNA - vagina [nTPM]":"6.2","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"1.5","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"7.8","Cell RNA - ASC TERT1 [nTPM]":"12.4","Cell RNA - BEWO [nTPM]":"75.6","Cell RNA - BJ [nTPM]":"10.1","Cell RNA - BJ hTERT+ [nTPM]":"10.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.4","Cell RNA - CACO-2 [nTPM]":"0.6","Cell RNA - CAPAN-2 [nTPM]":"0.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"12.8","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"3.0","Cell RNA - HBF TERT88 [nTPM]":"4.0","Cell RNA - HDLM-2 [nTPM]":"0.8","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"6.5","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"12.1","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.9","Cell RNA - hTERT-HME1 [nTPM]":"2.4","Cell RNA - hTERT-RPE1 [nTPM]":"6.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.7","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"11.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"2.8","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"1.7","Cell RNA - RT4 [nTPM]":"4.7","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.4","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"15.7","Cell RNA - U-138 MG [nTPM]":"2.2","Cell RNA - U-2 OS [nTPM]":"5.0","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"8.4","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"1.3","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"2.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"1.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"3.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.8","Single Cell Type RNA - Endothelial cells [nTPM]":"1.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"54.4","Single Cell Type RNA - Fibroblasts [nTPM]":"52.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.7","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"0.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"35.7","Single Cell Type RNA - Langerhans cells [nTPM]":"100.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"5.9","Single Cell Type RNA - Macrophages [nTPM]":"61.2","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"22.5","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"5.3","Single Cell Type RNA - Plasma cells [nTPM]":"1.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"18.7","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"MMP2","Gene synonym":["CLG4","CLG4A","TBE-1"],"Ensembl":"ENSG00000087245","Gene description":"Matrix metallopeptidase 2","Uniprot":["P08253"],"Chromosome":"16","Position":"55389700-55506691","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Angiogenesis","Collagen degradation"],"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"gallbladder":"1062.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"222.4","Extravillous trophoblasts":"467.9","Fibroblasts":"815.9","Leydig cells":"340.2","Peritubular cells":"419.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"5619.3","ASC TERT1":"1623.2","hTERT-RPE1":"6400.4","U-87 MG":"1812.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001939","CAB002788"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":1600000000,"Blood concentration - Conc. blood MS [pg\/L]":"220000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB002788":null,"HPA001939":"AB_1079395"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Tissue RNA - adipose tissue [nTPM]":"518.9","Tissue RNA - adrenal gland [nTPM]":"68.3","Tissue RNA - amygdala [nTPM]":"3.9","Tissue RNA - appendix [nTPM]":"135.1","Tissue RNA - basal ganglia [nTPM]":"4.0","Tissue RNA - bone marrow [nTPM]":"1.2","Tissue RNA - breast [nTPM]":"328.9","Tissue RNA - cerebellum [nTPM]":"4.9","Tissue RNA - cerebral cortex [nTPM]":"7.8","Tissue RNA - cervix [nTPM]":"514.1","Tissue RNA - choroid plexus [nTPM]":"9.4","Tissue RNA - colon [nTPM]":"173.8","Tissue RNA - duodenum [nTPM]":"57.4","Tissue RNA - endometrium 1 [nTPM]":"453.6","Tissue RNA - epididymis [nTPM]":"192.6","Tissue RNA - esophagus [nTPM]":"121.5","Tissue RNA - fallopian tube [nTPM]":"190.6","Tissue RNA - gallbladder [nTPM]":"1062.9","Tissue RNA - heart muscle [nTPM]":"212.8","Tissue RNA - hippocampal formation [nTPM]":"3.6","Tissue RNA - hypothalamus [nTPM]":"5.3","Tissue RNA - kidney [nTPM]":"43.7","Tissue RNA - liver [nTPM]":"15.6","Tissue RNA - lung [nTPM]":"279.7","Tissue RNA - lymph node [nTPM]":"28.1","Tissue RNA - medulla oblongata [nTPM]":"7.6","Tissue RNA - midbrain [nTPM]":"4.9","Tissue RNA - ovary [nTPM]":"271.1","Tissue RNA - pancreas [nTPM]":"42.8","Tissue RNA - parathyroid gland [nTPM]":"13.8","Tissue RNA - pituitary gland [nTPM]":"14.7","Tissue RNA - placenta [nTPM]":"225.0","Tissue RNA - pons [nTPM]":"5.4","Tissue RNA - prostate [nTPM]":"116.8","Tissue RNA - rectum [nTPM]":"171.3","Tissue RNA - retina [nTPM]":"11.4","Tissue RNA - salivary gland [nTPM]":"124.1","Tissue RNA - seminal vesicle [nTPM]":"137.5","Tissue RNA - skeletal muscle [nTPM]":"60.8","Tissue RNA - skin 1 [nTPM]":"455.6","Tissue RNA - small intestine [nTPM]":"177.3","Tissue RNA - smooth muscle [nTPM]":"468.5","Tissue RNA - spinal cord [nTPM]":"6.7","Tissue RNA - spleen [nTPM]":"58.3","Tissue RNA - stomach 1 [nTPM]":"134.0","Tissue RNA - testis [nTPM]":"49.6","Tissue RNA - thalamus [nTPM]":"8.6","Tissue RNA - thymus [nTPM]":"19.8","Tissue RNA - thyroid gland [nTPM]":"113.5","Tissue RNA - tongue [nTPM]":"66.1","Tissue RNA - tonsil [nTPM]":"30.3","Tissue RNA - urinary bladder [nTPM]":"660.8","Tissue RNA - vagina [nTPM]":"238.1","Tissue RNA - white matter [nTPM]":"10.0","Cell RNA - A-431 [nTPM]":"6.5","Cell RNA - A549 [nTPM]":"3.9","Cell RNA - AF22 [nTPM]":"192.0","Cell RNA - AN3-CA [nTPM]":"2.4","Cell RNA - ASC diff [nTPM]":"5619.3","Cell RNA - ASC TERT1 [nTPM]":"1623.2","Cell RNA - BEWO [nTPM]":"312.7","Cell RNA - BJ [nTPM]":"501.4","Cell RNA - BJ hTERT+ [nTPM]":"1146.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"99.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"79.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"2.1","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"391.7","Cell RNA - fHDF\/TERT166 [nTPM]":"891.0","Cell RNA - GAMG [nTPM]":"37.0","Cell RNA - HaCaT [nTPM]":"54.2","Cell RNA - HAP1 [nTPM]":"1.2","Cell RNA - HBEC3-KT [nTPM]":"4.6","Cell RNA - HBF TERT88 [nTPM]":"57.0","Cell RNA - HDLM-2 [nTPM]":"0.7","Cell RNA - HEK 293 [nTPM]":"0.9","Cell RNA - HEL [nTPM]":"0.7","Cell RNA - HeLa [nTPM]":"12.9","Cell RNA - Hep G2 [nTPM]":"3.0","Cell RNA - HHSteC [nTPM]":"530.6","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"14.8","Cell RNA - HSkMC [nTPM]":"1396.8","Cell RNA - hTCEpi [nTPM]":"1.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"512.4","Cell RNA - hTERT-HME1 [nTPM]":"4.4","Cell RNA - hTERT-RPE1 [nTPM]":"6400.4","Cell RNA - HUVEC TERT2 [nTPM]":"651.1","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"2.4","Cell RNA - LHCN-M2 [nTPM]":"334.7","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"8.2","Cell RNA - NTERA-2 [nTPM]":"152.4","Cell RNA - OE19 [nTPM]":"0.5","Cell RNA - PC-3 [nTPM]":"1.6","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"46.1","Cell RNA - RPMI-8226 [nTPM]":"0.9","Cell RNA - RPTEC TERT1 [nTPM]":"16.1","Cell RNA - RT4 [nTPM]":"7.6","Cell RNA - SCLC-21H [nTPM]":"3.2","Cell RNA - SH-SY5Y [nTPM]":"345.0","Cell RNA - SiHa [nTPM]":"93.3","Cell RNA - SK-BR-3 [nTPM]":"0.8","Cell RNA - SK-MEL-30 [nTPM]":"2.1","Cell RNA - SuSa [nTPM]":"849.0","Cell RNA - T-47d [nTPM]":"1.6","Cell RNA - THP-1 [nTPM]":"36.0","Cell RNA - TIME [nTPM]":"924.6","Cell RNA - U-138 MG [nTPM]":"1546.0","Cell RNA - U-2 OS [nTPM]":"144.9","Cell RNA - U-2197 [nTPM]":"300.5","Cell RNA - U-251 MG [nTPM]":"66.9","Cell RNA - U-266\/70 [nTPM]":"1.0","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"2.2","Cell RNA - U-87 MG [nTPM]":"1812.3","Cell RNA - U-937 [nTPM]":"28.3","Cell RNA - WM-115 [nTPM]":"289.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.9","Brain RNA - basal ganglia [nTPM]":"4.0","Brain RNA - cerebellum [nTPM]":"4.9","Brain RNA - cerebral cortex [nTPM]":"7.8","Brain RNA - hippocampal formation [nTPM]":"3.6","Brain RNA - hypothalamus [nTPM]":"5.3","Brain RNA - medulla oblongata [nTPM]":"7.6","Brain RNA - midbrain [nTPM]":"4.9","Brain RNA - pons [nTPM]":"5.4","Brain RNA - spinal cord [nTPM]":"6.7","Brain RNA - thalamus [nTPM]":"8.6","Brain RNA - white matter [nTPM]":"10.0","Single Cell Type RNA - Adipocytes [nTPM]":"38.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"122.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"48.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"30.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.5","Single Cell Type RNA - Early spermatids [nTPM]":"12.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"222.4","Single Cell Type RNA - Endothelial cells [nTPM]":"46.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"28.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"467.9","Single Cell Type RNA - Fibroblasts [nTPM]":"815.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.2","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"180.7","Single Cell Type RNA - Late spermatids [nTPM]":"40.2","Single Cell Type RNA - Leydig cells [nTPM]":"340.2","Single Cell Type RNA - Macrophages [nTPM]":"11.8","Single Cell Type RNA - Melanocytes [nTPM]":"128.1","Single Cell Type RNA - Microglial cells [nTPM]":"27.2","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"7.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"419.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"80.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"65.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.2","Single Cell Type RNA - Spermatogonia [nTPM]":"2.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"102.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.2","Single Cell Type RNA - T-cells [nTPM]":"10.3","Single Cell Type RNA - Theca cells [nTPM]":"35.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"4.4"},{"Gene":"MMP20","Gene synonym":[],"Ensembl":"ENSG00000137674","Gene description":"Matrix metallopeptidase 20","Uniprot":["O60882"],"Chromosome":"11","Position":"102576832-102625332","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Amelogenesis imperfecta"],"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Early spermatids":"91.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"OE19":"2.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 23: Spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-3"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-3"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"2.5","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"91.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"12.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"MMP21","Gene synonym":[],"Ensembl":"ENSG00000154485","Gene description":"Matrix metallopeptidase 21","Uniprot":["Q8N119"],"Chromosome":"10","Position":"125753580-125775821","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Heterotaxy"],"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"epididymis":"53.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"1.9","Granulosa cells":"1.4","Microglial cells":"1.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"0.7","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"1.7","Tissue RNA - cerebral cortex [nTPM]":"0.7","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"0.5","Tissue RNA - epididymis [nTPM]":"53.9","Tissue RNA - esophagus [nTPM]":"0.5","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"0.7","Tissue RNA - heart muscle [nTPM]":"0.8","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.4","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"1.0","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"3.7","Tissue RNA - pancreas [nTPM]":"0.7","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"1.8","Tissue RNA - salivary gland [nTPM]":"1.2","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"1.2","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.6","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"0.5","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.5","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.9","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.6","Cell RNA - BJ [nTPM]":"0.4","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.8","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.9","Cell RNA - Hep G2 [nTPM]":"0.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.5","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.7","Brain RNA - cerebellum [nTPM]":"1.7","Brain RNA - cerebral cortex [nTPM]":"0.7","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.4","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.5","Brain RNA - white matter [nTPM]":"0.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"MMP3","Gene synonym":["STMY","STMY1"],"Ensembl":"ENSG00000149968","Gene description":"Matrix metallopeptidase 3","Uniprot":["P08254"],"Chromosome":"11","Position":"102835801-102843609","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Collagen degradation"],"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"90.7","salivary gland":"286.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"20.4","Basal respiratory cells":"25.8","Early spermatids":"24.2","Extravillous trophoblasts":"13.4","Fibroblasts":"17.9","Prostatic glandular cells":"11.9","Smooth muscle cells":"10.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"59.9"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"thalamus":"7.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"18","RNA cell line specific nTPM":{"BJ":"1545.7","BJ hTERT+":"4229.3","fHDF\/TERT166":"1846.6"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"hippocampal formation":"3.2"},"Antibody":["HPA007875"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":2540000,"Blood concentration - Conc. blood MS [pg\/L]":"460000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA007875":"AB_1079396"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.73e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.09e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-15"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Tissue RNA - adipose tissue [nTPM]":"90.7","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"20.1","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"36.6","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"1.6","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"6.1","Tissue RNA - duodenum [nTPM]":"2.4","Tissue RNA - endometrium 1 [nTPM]":"38.1","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.8","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"1.9","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"1.6","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"1.6","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.9","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"2.2","Tissue RNA - rectum [nTPM]":"2.3","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"286.1","Tissue RNA - seminal vesicle [nTPM]":"2.2","Tissue RNA - skeletal muscle [nTPM]":"39.6","Tissue RNA - skin 1 [nTPM]":"63.7","Tissue RNA - small intestine [nTPM]":"4.5","Tissue RNA - smooth muscle [nTPM]":"1.6","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"10.5","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"7.3","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"2.6","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"1.3","Tissue RNA - urinary bladder [nTPM]":"13.9","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.4","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"1545.7","Cell RNA - BJ hTERT+ [nTPM]":"4229.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"27.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.7","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"1846.6","Cell RNA - GAMG [nTPM]":"96.9","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"45.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"1.0","Cell RNA - HHSteC [nTPM]":"0.7","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"4.6","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"122.0","Cell RNA - hTERT-HME1 [nTPM]":"5.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"4.7","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.4","Cell RNA - PC-3 [nTPM]":"0.9","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"2.3","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.9","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"140.5","Cell RNA - U-2 OS [nTPM]":"13.1","Cell RNA - U-2197 [nTPM]":"1.6","Cell RNA - U-251 MG [nTPM]":"0.5","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"56.8","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"7.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"1.6","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"1.6","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"7.3","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"25.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"7.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"24.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.4","Single Cell Type RNA - Fibroblasts [nTPM]":"17.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"2.2","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.5","Single Cell Type RNA - Paneth cells [nTPM]":"4.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"1.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.8","Single Cell Type RNA - Urothelial cells [nTPM]":"7.4"},{"Gene":"MOCOS","Gene synonym":["FLJ20733","HMCS","MOS"],"Ensembl":"ENSG00000075643","Gene description":"Molybdenum cofactor sulfurase","Uniprot":["Q96EN8"],"Chromosome":"18","Position":"36187497-36272157","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Molybdenum cofactor biosynthesis"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"10.3","liver":"16.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Glandular and luminal cells":"18.8","Hepatocytes":"39.4","Proximal enterocytes":"22.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTCEpi":"40.7","hTERT-HME1":"49.7","SiHa":"54.9","SK-MEL-30":"38.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039412","HPA047958"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA039412":"AB_2676496","HPA047958":"AB_2680225"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.55e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.29e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.03e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.35e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.0","Tissue RNA - adrenal gland [nTPM]":"10.3","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.9","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"2.5","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"0.9","Tissue RNA - choroid plexus [nTPM]":"0.5","Tissue RNA - colon [nTPM]":"1.6","Tissue RNA - duodenum [nTPM]":"6.1","Tissue RNA - endometrium 1 [nTPM]":"0.8","Tissue RNA - epididymis [nTPM]":"1.9","Tissue RNA - esophagus [nTPM]":"3.8","Tissue RNA - fallopian tube [nTPM]":"1.7","Tissue RNA - gallbladder [nTPM]":"1.4","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"0.4","Tissue RNA - kidney [nTPM]":"1.2","Tissue RNA - liver [nTPM]":"16.0","Tissue RNA - lung [nTPM]":"1.6","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"1.2","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"6.4","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"2.3","Tissue RNA - pituitary gland [nTPM]":"2.0","Tissue RNA - placenta [nTPM]":"1.0","Tissue RNA - pons [nTPM]":"1.3","Tissue RNA - prostate [nTPM]":"1.3","Tissue RNA - rectum [nTPM]":"1.6","Tissue RNA - retina [nTPM]":"0.7","Tissue RNA - salivary gland [nTPM]":"1.8","Tissue RNA - seminal vesicle [nTPM]":"3.3","Tissue RNA - skeletal muscle [nTPM]":"0.6","Tissue RNA - skin 1 [nTPM]":"2.0","Tissue RNA - small intestine [nTPM]":"6.4","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"1.6","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"1.2","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"1.2","Tissue RNA - urinary bladder [nTPM]":"2.7","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"14.3","Cell RNA - A549 [nTPM]":"4.8","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"4.3","Cell RNA - ASC TERT1 [nTPM]":"5.5","Cell RNA - BEWO [nTPM]":"2.9","Cell RNA - BJ [nTPM]":"8.2","Cell RNA - BJ hTERT+ [nTPM]":"4.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.0","Cell RNA - CACO-2 [nTPM]":"3.1","Cell RNA - CAPAN-2 [nTPM]":"4.4","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"2.5","Cell RNA - fHDF\/TERT166 [nTPM]":"13.4","Cell RNA - GAMG [nTPM]":"1.0","Cell RNA - HaCaT [nTPM]":"8.6","Cell RNA - HAP1 [nTPM]":"2.9","Cell RNA - HBEC3-KT [nTPM]":"12.9","Cell RNA - HBF TERT88 [nTPM]":"5.4","Cell RNA - HDLM-2 [nTPM]":"2.4","Cell RNA - HEK 293 [nTPM]":"2.3","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"13.5","Cell RNA - Hep G2 [nTPM]":"11.8","Cell RNA - HHSteC [nTPM]":"14.6","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"3.8","Cell RNA - HSkMC [nTPM]":"8.7","Cell RNA - hTCEpi [nTPM]":"40.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.2","Cell RNA - hTERT-HME1 [nTPM]":"49.7","Cell RNA - hTERT-RPE1 [nTPM]":"0.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.6","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"4.9","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"6.2","Cell RNA - MCF7 [nTPM]":"3.6","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"3.4","Cell RNA - PC-3 [nTPM]":"4.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"5.5","Cell RNA - RT4 [nTPM]":"18.5","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"1.2","Cell RNA - SiHa [nTPM]":"54.9","Cell RNA - SK-BR-3 [nTPM]":"3.3","Cell RNA - SK-MEL-30 [nTPM]":"38.8","Cell RNA - SuSa [nTPM]":"0.9","Cell RNA - T-47d [nTPM]":"2.5","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"2.7","Cell RNA - U-138 MG [nTPM]":"3.0","Cell RNA - U-2 OS [nTPM]":"3.7","Cell RNA - U-2197 [nTPM]":"6.7","Cell RNA - U-251 MG [nTPM]":"1.4","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"7.8","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"1.3","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"0.4","Brain RNA - medulla oblongata [nTPM]":"1.2","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"1.3","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"6.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.1","Single Cell Type RNA - Early spermatids [nTPM]":"7.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.3","Single Cell Type RNA - Fibroblasts [nTPM]":"2.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"39.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.1","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"2.6","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"11.9","Single Cell Type RNA - Muller glia cells [nTPM]":"6.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.6","Single Cell Type RNA - Paneth cells [nTPM]":"2.3","Single Cell Type RNA - Peritubular cells [nTPM]":"9.1","Single Cell Type RNA - Plasma cells [nTPM]":"0.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.3","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"2.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.5","Single Cell Type RNA - Urothelial cells [nTPM]":"2.2"},{"Gene":"MOCS1","Gene synonym":["MOCOD"],"Ensembl":"ENSG00000124615","Gene description":"Molybdenum cofactor synthesis 1","Uniprot":["Q9NZB8"],"Chromosome":"6","Position":"39899578-39934551","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Molybdenum cofactor biosynthesis"],"Molecular function":["Lyase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"33.7","Hepatocytes":"36.2","Sertoli cells":"78.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"40.4","JURKAT":"51.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045783","HPA058177","HPA075505"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA045783":"AB_10960058","HPA058177":"AB_2683629","HPA075505":"AB_2686751"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.07e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.07e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-2"},"Tissue RNA - adipose tissue [nTPM]":"33.7","Tissue RNA - adrenal gland [nTPM]":"9.5","Tissue RNA - amygdala [nTPM]":"14.6","Tissue RNA - appendix [nTPM]":"3.2","Tissue RNA - basal ganglia [nTPM]":"17.9","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"26.8","Tissue RNA - cerebellum [nTPM]":"16.8","Tissue RNA - cerebral cortex [nTPM]":"14.7","Tissue RNA - cervix [nTPM]":"8.8","Tissue RNA - choroid plexus [nTPM]":"11.2","Tissue RNA - colon [nTPM]":"11.7","Tissue RNA - duodenum [nTPM]":"16.2","Tissue RNA - endometrium 1 [nTPM]":"10.0","Tissue RNA - epididymis [nTPM]":"10.1","Tissue RNA - esophagus [nTPM]":"6.7","Tissue RNA - fallopian tube [nTPM]":"10.3","Tissue RNA - gallbladder [nTPM]":"5.5","Tissue RNA - heart muscle [nTPM]":"22.0","Tissue RNA - hippocampal formation [nTPM]":"12.7","Tissue RNA - hypothalamus [nTPM]":"16.0","Tissue RNA - kidney [nTPM]":"20.4","Tissue RNA - liver [nTPM]":"40.3","Tissue RNA - lung [nTPM]":"22.9","Tissue RNA - lymph node [nTPM]":"4.5","Tissue RNA - medulla oblongata [nTPM]":"17.4","Tissue RNA - midbrain [nTPM]":"18.8","Tissue RNA - ovary [nTPM]":"9.0","Tissue RNA - pancreas [nTPM]":"11.9","Tissue RNA - parathyroid gland [nTPM]":"9.6","Tissue RNA - pituitary gland [nTPM]":"5.3","Tissue RNA - placenta [nTPM]":"35.6","Tissue RNA - pons [nTPM]":"16.2","Tissue RNA - prostate [nTPM]":"5.3","Tissue RNA - rectum [nTPM]":"5.6","Tissue RNA - retina [nTPM]":"3.0","Tissue RNA - salivary gland [nTPM]":"6.1","Tissue RNA - seminal vesicle [nTPM]":"7.5","Tissue RNA - skeletal muscle [nTPM]":"25.7","Tissue RNA - skin 1 [nTPM]":"7.3","Tissue RNA - small intestine [nTPM]":"12.7","Tissue RNA - smooth muscle [nTPM]":"9.2","Tissue RNA - spinal cord [nTPM]":"15.6","Tissue RNA - spleen [nTPM]":"2.6","Tissue RNA - stomach 1 [nTPM]":"7.6","Tissue RNA - testis [nTPM]":"3.2","Tissue RNA - thalamus [nTPM]":"17.3","Tissue RNA - thymus [nTPM]":"3.3","Tissue RNA - thyroid gland [nTPM]":"16.0","Tissue RNA - tongue [nTPM]":"45.0","Tissue RNA - tonsil [nTPM]":"3.4","Tissue RNA - urinary bladder [nTPM]":"10.0","Tissue RNA - vagina [nTPM]":"6.6","Tissue RNA - white matter [nTPM]":"16.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"2.1","Cell RNA - AF22 [nTPM]":"7.0","Cell RNA - AN3-CA [nTPM]":"11.4","Cell RNA - ASC diff [nTPM]":"19.3","Cell RNA - ASC TERT1 [nTPM]":"7.2","Cell RNA - BEWO [nTPM]":"15.2","Cell RNA - BJ [nTPM]":"8.7","Cell RNA - BJ hTERT+ [nTPM]":"15.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.0","Cell RNA - CACO-2 [nTPM]":"40.4","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"8.4","Cell RNA - fHDF\/TERT166 [nTPM]":"7.4","Cell RNA - GAMG [nTPM]":"7.0","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"8.2","Cell RNA - HBEC3-KT [nTPM]":"9.8","Cell RNA - HBF TERT88 [nTPM]":"8.7","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"8.6","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"13.7","Cell RNA - HHSteC [nTPM]":"12.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"3.1","Cell RNA - HSkMC [nTPM]":"12.0","Cell RNA - hTCEpi [nTPM]":"3.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.9","Cell RNA - hTERT-HME1 [nTPM]":"4.2","Cell RNA - hTERT-RPE1 [nTPM]":"7.2","Cell RNA - HUVEC TERT2 [nTPM]":"10.1","Cell RNA - JURKAT [nTPM]":"51.1","Cell RNA - K-562 [nTPM]":"8.4","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"11.7","Cell RNA - MCF7 [nTPM]":"5.0","Cell RNA - MOLT-4 [nTPM]":"16.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"7.9","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"4.6","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"6.3","Cell RNA - RPMI-8226 [nTPM]":"1.1","Cell RNA - RPTEC TERT1 [nTPM]":"7.6","Cell RNA - RT4 [nTPM]":"8.2","Cell RNA - SCLC-21H [nTPM]":"6.1","Cell RNA - SH-SY5Y [nTPM]":"8.5","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"4.2","Cell RNA - SK-MEL-30 [nTPM]":"7.0","Cell RNA - SuSa [nTPM]":"6.3","Cell RNA - T-47d [nTPM]":"5.2","Cell RNA - THP-1 [nTPM]":"1.4","Cell RNA - TIME [nTPM]":"16.2","Cell RNA - U-138 MG [nTPM]":"12.2","Cell RNA - U-2 OS [nTPM]":"9.8","Cell RNA - U-2197 [nTPM]":"7.7","Cell RNA - U-251 MG [nTPM]":"4.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"1.7","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"4.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"14.6","Brain RNA - basal ganglia [nTPM]":"17.9","Brain RNA - cerebellum [nTPM]":"16.8","Brain RNA - cerebral cortex [nTPM]":"14.7","Brain RNA - hippocampal formation [nTPM]":"12.7","Brain RNA - hypothalamus [nTPM]":"16.0","Brain RNA - medulla oblongata [nTPM]":"17.4","Brain RNA - midbrain [nTPM]":"18.8","Brain RNA - pons [nTPM]":"16.2","Brain RNA - spinal cord [nTPM]":"15.6","Brain RNA - thalamus [nTPM]":"17.3","Brain RNA - white matter [nTPM]":"16.4","Single Cell Type RNA - Adipocytes [nTPM]":"5.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.5","Single Cell Type RNA - Astrocytes [nTPM]":"6.2","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"1.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"0.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"33.7","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.6","Single Cell Type RNA - Endothelial cells [nTPM]":"3.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.3","Single Cell Type RNA - Fibroblasts [nTPM]":"4.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.4","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"6.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"36.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.9","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.8","Single Cell Type RNA - Langerhans cells [nTPM]":"1.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.8","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.0","Single Cell Type RNA - Paneth cells [nTPM]":"9.1","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.2","Single Cell Type RNA - Sertoli cells [nTPM]":"78.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.6","Single Cell Type RNA - Spermatogonia [nTPM]":"1.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.2","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"MOCS2","Gene synonym":["MOCO1","MOCS2A","MOCS2B"],"Ensembl":"ENSG00000164172","Gene description":"Molybdenum cofactor synthesis 2","Uniprot":["O96007","O96033"],"Chromosome":"5","Position":"53095679-53110063","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Molybdenum cofactor biosynthesis"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"573.2","Proximal tubular cells":"281.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037679","HPA037680"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear speckles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm","Nuclear speckles"],"Antibody RRID":{"HPA037679":"AB_2675604","HPA037680":"AB_10673635"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.68e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Tissue RNA - adipose tissue [nTPM]":"48.7","Tissue RNA - adrenal gland [nTPM]":"79.4","Tissue RNA - amygdala [nTPM]":"79.1","Tissue RNA - appendix [nTPM]":"24.9","Tissue RNA - basal ganglia [nTPM]":"84.9","Tissue RNA - bone marrow [nTPM]":"9.1","Tissue RNA - breast [nTPM]":"42.1","Tissue RNA - cerebellum [nTPM]":"80.3","Tissue RNA - cerebral cortex [nTPM]":"107.6","Tissue RNA - cervix [nTPM]":"34.7","Tissue RNA - choroid plexus [nTPM]":"74.4","Tissue RNA - colon [nTPM]":"41.9","Tissue RNA - duodenum [nTPM]":"40.8","Tissue RNA - endometrium 1 [nTPM]":"30.0","Tissue RNA - epididymis [nTPM]":"45.9","Tissue RNA - esophagus [nTPM]":"35.2","Tissue RNA - fallopian tube [nTPM]":"26.5","Tissue RNA - gallbladder [nTPM]":"31.3","Tissue RNA - heart muscle [nTPM]":"87.0","Tissue RNA - hippocampal formation [nTPM]":"84.3","Tissue RNA - hypothalamus [nTPM]":"86.3","Tissue RNA - kidney [nTPM]":"114.8","Tissue RNA - liver [nTPM]":"126.2","Tissue RNA - lung [nTPM]":"28.2","Tissue RNA - lymph node [nTPM]":"26.1","Tissue RNA - medulla oblongata [nTPM]":"79.2","Tissue RNA - midbrain [nTPM]":"80.5","Tissue RNA - ovary [nTPM]":"43.5","Tissue RNA - pancreas [nTPM]":"42.4","Tissue RNA - parathyroid gland [nTPM]":"89.6","Tissue RNA - pituitary gland [nTPM]":"30.5","Tissue RNA - placenta [nTPM]":"35.9","Tissue RNA - pons [nTPM]":"82.4","Tissue RNA - prostate [nTPM]":"36.8","Tissue RNA - rectum [nTPM]":"32.3","Tissue RNA - retina [nTPM]":"59.3","Tissue RNA - salivary gland [nTPM]":"48.9","Tissue RNA - seminal vesicle [nTPM]":"44.9","Tissue RNA - skeletal muscle [nTPM]":"109.3","Tissue RNA - skin 1 [nTPM]":"16.6","Tissue RNA - small intestine [nTPM]":"40.2","Tissue RNA - smooth muscle [nTPM]":"34.4","Tissue RNA - spinal cord [nTPM]":"85.6","Tissue RNA - spleen [nTPM]":"23.6","Tissue RNA - stomach 1 [nTPM]":"37.2","Tissue RNA - testis [nTPM]":"26.0","Tissue RNA - thalamus [nTPM]":"88.0","Tissue RNA - thymus [nTPM]":"28.3","Tissue RNA - thyroid gland [nTPM]":"55.4","Tissue RNA - tongue [nTPM]":"111.8","Tissue RNA - tonsil [nTPM]":"25.2","Tissue RNA - urinary bladder [nTPM]":"30.8","Tissue RNA - vagina [nTPM]":"24.6","Tissue RNA - white matter [nTPM]":"87.4","Cell RNA - A-431 [nTPM]":"79.4","Cell RNA - A549 [nTPM]":"62.7","Cell RNA - AF22 [nTPM]":"42.9","Cell RNA - AN3-CA [nTPM]":"109.9","Cell RNA - ASC diff [nTPM]":"85.0","Cell RNA - ASC TERT1 [nTPM]":"83.2","Cell RNA - BEWO [nTPM]":"51.6","Cell RNA - BJ [nTPM]":"99.5","Cell RNA - BJ hTERT+ [nTPM]":"91.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"74.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"89.8","Cell RNA - CACO-2 [nTPM]":"79.7","Cell RNA - CAPAN-2 [nTPM]":"56.5","Cell RNA - Daudi [nTPM]":"76.7","Cell RNA - EFO-21 [nTPM]":"143.5","Cell RNA - fHDF\/TERT166 [nTPM]":"69.9","Cell RNA - GAMG [nTPM]":"127.1","Cell RNA - HaCaT [nTPM]":"45.0","Cell RNA - HAP1 [nTPM]":"91.7","Cell RNA - HBEC3-KT [nTPM]":"96.7","Cell RNA - HBF TERT88 [nTPM]":"117.2","Cell RNA - HDLM-2 [nTPM]":"19.6","Cell RNA - HEK 293 [nTPM]":"84.8","Cell RNA - HEL [nTPM]":"61.7","Cell RNA - HeLa [nTPM]":"58.2","Cell RNA - Hep G2 [nTPM]":"75.9","Cell RNA - HHSteC [nTPM]":"94.4","Cell RNA - HL-60 [nTPM]":"65.0","Cell RNA - HMC-1 [nTPM]":"43.0","Cell RNA - HSkMC [nTPM]":"65.1","Cell RNA - hTCEpi [nTPM]":"41.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"91.7","Cell RNA - hTERT-HME1 [nTPM]":"83.5","Cell RNA - hTERT-RPE1 [nTPM]":"81.0","Cell RNA - HUVEC TERT2 [nTPM]":"85.1","Cell RNA - JURKAT [nTPM]":"101.4","Cell RNA - K-562 [nTPM]":"58.7","Cell RNA - Karpas-707 [nTPM]":"44.2","Cell RNA - LHCN-M2 [nTPM]":"129.5","Cell RNA - MCF7 [nTPM]":"115.5","Cell RNA - MOLT-4 [nTPM]":"72.7","Cell RNA - NB-4 [nTPM]":"31.8","Cell RNA - NTERA-2 [nTPM]":"37.0","Cell RNA - OE19 [nTPM]":"34.2","Cell RNA - PC-3 [nTPM]":"130.1","Cell RNA - REH [nTPM]":"36.0","Cell RNA - RH-30 [nTPM]":"93.0","Cell RNA - RPMI-8226 [nTPM]":"67.0","Cell RNA - RPTEC TERT1 [nTPM]":"144.1","Cell RNA - RT4 [nTPM]":"56.6","Cell RNA - SCLC-21H [nTPM]":"29.4","Cell RNA - SH-SY5Y [nTPM]":"33.7","Cell RNA - SiHa [nTPM]":"69.4","Cell RNA - SK-BR-3 [nTPM]":"57.3","Cell RNA - SK-MEL-30 [nTPM]":"72.9","Cell RNA - SuSa [nTPM]":"56.9","Cell RNA - T-47d [nTPM]":"107.2","Cell RNA - THP-1 [nTPM]":"15.4","Cell RNA - TIME [nTPM]":"55.6","Cell RNA - U-138 MG [nTPM]":"76.9","Cell RNA - U-2 OS [nTPM]":"81.0","Cell RNA - U-2197 [nTPM]":"69.1","Cell RNA - U-251 MG [nTPM]":"120.5","Cell RNA - U-266\/70 [nTPM]":"49.4","Cell RNA - U-266\/84 [nTPM]":"84.8","Cell RNA - U-698 [nTPM]":"91.5","Cell RNA - U-87 MG [nTPM]":"106.7","Cell RNA - U-937 [nTPM]":"16.8","Cell RNA - WM-115 [nTPM]":"125.1","Blood RNA - basophil [nTPM]":"14.5","Blood RNA - classical monocyte [nTPM]":"21.8","Blood RNA - eosinophil [nTPM]":"15.6","Blood RNA - gdT-cell [nTPM]":"36.9","Blood RNA - intermediate monocyte [nTPM]":"26.9","Blood RNA - MAIT T-cell [nTPM]":"46.2","Blood RNA - memory B-cell [nTPM]":"37.5","Blood RNA - memory CD4 T-cell [nTPM]":"42.7","Blood RNA - memory CD8 T-cell [nTPM]":"42.8","Blood RNA - myeloid DC [nTPM]":"29.8","Blood RNA - naive B-cell [nTPM]":"40.5","Blood RNA - naive CD4 T-cell [nTPM]":"55.3","Blood RNA - naive CD8 T-cell [nTPM]":"49.2","Blood RNA - neutrophil [nTPM]":"3.8","Blood RNA - NK-cell [nTPM]":"43.5","Blood RNA - non-classical monocyte [nTPM]":"25.4","Blood RNA - plasmacytoid DC [nTPM]":"27.8","Blood RNA - T-reg [nTPM]":"44.9","Blood RNA - total PBMC [nTPM]":"28.9","Brain RNA - amygdala [nTPM]":"79.1","Brain RNA - basal ganglia [nTPM]":"84.9","Brain RNA - cerebellum [nTPM]":"80.3","Brain RNA - cerebral cortex [nTPM]":"107.6","Brain RNA - hippocampal formation [nTPM]":"84.3","Brain RNA - hypothalamus [nTPM]":"86.3","Brain RNA - medulla oblongata [nTPM]":"79.2","Brain RNA - midbrain [nTPM]":"80.5","Brain RNA - pons [nTPM]":"82.4","Brain RNA - spinal cord [nTPM]":"85.6","Brain RNA - thalamus [nTPM]":"88.0","Brain RNA - white matter [nTPM]":"87.4","Single Cell Type RNA - Adipocytes [nTPM]":"51.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"54.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.7","Single Cell Type RNA - Astrocytes [nTPM]":"14.4","Single Cell Type RNA - B-cells [nTPM]":"23.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"40.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"48.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.9","Single Cell Type RNA - Bipolar cells [nTPM]":"30.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"55.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"50.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"122.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"62.9","Single Cell Type RNA - Club cells [nTPM]":"37.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"69.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"95.4","Single Cell Type RNA - dendritic cells [nTPM]":"19.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"573.2","Single Cell Type RNA - Ductal cells [nTPM]":"43.7","Single Cell Type RNA - Early spermatids [nTPM]":"7.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.0","Single Cell Type RNA - Endothelial cells [nTPM]":"37.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"26.4","Single Cell Type RNA - Erythroid cells [nTPM]":"18.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"43.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"37.3","Single Cell Type RNA - Fibroblasts [nTPM]":"55.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.8","Single Cell Type RNA - granulocytes [nTPM]":"10.1","Single Cell Type RNA - Granulosa cells [nTPM]":"38.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.0","Single Cell Type RNA - Hepatocytes [nTPM]":"132.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"41.3","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"22.7","Single Cell Type RNA - Ionocytes [nTPM]":"44.7","Single Cell Type RNA - Kupffer cells [nTPM]":"31.2","Single Cell Type RNA - Langerhans cells [nTPM]":"20.1","Single Cell Type RNA - Late spermatids [nTPM]":"14.6","Single Cell Type RNA - Leydig cells [nTPM]":"50.7","Single Cell Type RNA - Macrophages [nTPM]":"28.7","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"12.2","Single Cell Type RNA - Muller glia cells [nTPM]":"67.5","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.1","Single Cell Type RNA - Paneth cells [nTPM]":"18.2","Single Cell Type RNA - Peritubular cells [nTPM]":"68.8","Single Cell Type RNA - Plasma cells [nTPM]":"26.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"34.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"65.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"281.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"32.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.7","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"73.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"49.4","Single Cell Type RNA - Spermatocytes [nTPM]":"46.7","Single Cell Type RNA - Spermatogonia [nTPM]":"62.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"37.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"32.3","Single Cell Type RNA - T-cells [nTPM]":"25.8","Single Cell Type RNA - Theca cells [nTPM]":"64.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"30.9","Single Cell Type RNA - Urothelial cells [nTPM]":"34.5"},{"Gene":"MOGS","Gene synonym":["CWH41","DER7","GCS1"],"Ensembl":"ENSG00000115275","Gene description":"Mannosyl-oligosaccharide glucosidase","Uniprot":["Q13724"],"Chromosome":"2","Position":"74461057-74465410","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"222.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011322","HPA011969"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1500000","Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA011322":"AB_2668483","HPA011969":"AB_1849579"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.33e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.34e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.79e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-3"},"Tissue RNA - adipose tissue [nTPM]":"18.4","Tissue RNA - adrenal gland [nTPM]":"18.3","Tissue RNA - amygdala [nTPM]":"8.1","Tissue RNA - appendix [nTPM]":"20.2","Tissue RNA - basal ganglia [nTPM]":"9.1","Tissue RNA - bone marrow [nTPM]":"8.5","Tissue RNA - breast [nTPM]":"18.6","Tissue RNA - cerebellum [nTPM]":"9.0","Tissue RNA - cerebral cortex [nTPM]":"13.3","Tissue RNA - cervix [nTPM]":"19.2","Tissue RNA - choroid plexus [nTPM]":"9.2","Tissue RNA - colon [nTPM]":"22.8","Tissue RNA - duodenum [nTPM]":"41.7","Tissue RNA - endometrium 1 [nTPM]":"18.3","Tissue RNA - epididymis [nTPM]":"5.5","Tissue RNA - esophagus [nTPM]":"22.5","Tissue RNA - fallopian tube [nTPM]":"20.0","Tissue RNA - gallbladder [nTPM]":"14.4","Tissue RNA - heart muscle [nTPM]":"16.9","Tissue RNA - hippocampal formation [nTPM]":"8.3","Tissue RNA - hypothalamus [nTPM]":"9.0","Tissue RNA - kidney [nTPM]":"20.9","Tissue RNA - liver [nTPM]":"34.3","Tissue RNA - lung [nTPM]":"24.9","Tissue RNA - lymph node [nTPM]":"21.6","Tissue RNA - medulla oblongata [nTPM]":"9.4","Tissue RNA - midbrain [nTPM]":"8.7","Tissue RNA - ovary [nTPM]":"18.6","Tissue RNA - pancreas [nTPM]":"42.3","Tissue RNA - parathyroid gland [nTPM]":"21.5","Tissue RNA - pituitary gland [nTPM]":"21.7","Tissue RNA - placenta [nTPM]":"34.5","Tissue RNA - pons [nTPM]":"9.9","Tissue RNA - prostate [nTPM]":"23.3","Tissue RNA - rectum [nTPM]":"13.4","Tissue RNA - retina [nTPM]":"9.6","Tissue RNA - salivary gland [nTPM]":"31.1","Tissue RNA - seminal vesicle [nTPM]":"14.6","Tissue RNA - skeletal muscle [nTPM]":"21.3","Tissue RNA - skin 1 [nTPM]":"24.9","Tissue RNA - small intestine [nTPM]":"29.7","Tissue RNA - smooth muscle [nTPM]":"11.4","Tissue RNA - spinal cord [nTPM]":"9.3","Tissue RNA - spleen [nTPM]":"31.7","Tissue RNA - stomach 1 [nTPM]":"35.5","Tissue RNA - testis [nTPM]":"19.0","Tissue RNA - thalamus [nTPM]":"8.9","Tissue RNA - thymus [nTPM]":"19.8","Tissue RNA - thyroid gland [nTPM]":"21.9","Tissue RNA - tongue [nTPM]":"16.2","Tissue RNA - tonsil [nTPM]":"18.1","Tissue RNA - urinary bladder [nTPM]":"20.1","Tissue RNA - vagina [nTPM]":"19.1","Tissue RNA - white matter [nTPM]":"9.8","Cell RNA - A-431 [nTPM]":"53.1","Cell RNA - A549 [nTPM]":"46.2","Cell RNA - AF22 [nTPM]":"23.5","Cell RNA - AN3-CA [nTPM]":"29.6","Cell RNA - ASC diff [nTPM]":"55.3","Cell RNA - ASC TERT1 [nTPM]":"38.9","Cell RNA - BEWO [nTPM]":"90.1","Cell RNA - BJ [nTPM]":"38.7","Cell RNA - BJ hTERT+ [nTPM]":"58.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"59.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"58.2","Cell RNA - CACO-2 [nTPM]":"81.9","Cell RNA - CAPAN-2 [nTPM]":"58.7","Cell RNA - Daudi [nTPM]":"45.2","Cell RNA - EFO-21 [nTPM]":"34.9","Cell RNA - fHDF\/TERT166 [nTPM]":"36.3","Cell RNA - GAMG [nTPM]":"46.7","Cell RNA - HaCaT [nTPM]":"50.6","Cell RNA - HAP1 [nTPM]":"40.2","Cell RNA - HBEC3-KT [nTPM]":"43.3","Cell RNA - HBF TERT88 [nTPM]":"32.5","Cell RNA - HDLM-2 [nTPM]":"46.7","Cell RNA - HEK 293 [nTPM]":"39.9","Cell RNA - HEL [nTPM]":"20.3","Cell RNA - HeLa [nTPM]":"14.4","Cell RNA - Hep G2 [nTPM]":"68.6","Cell RNA - HHSteC [nTPM]":"54.9","Cell RNA - HL-60 [nTPM]":"49.8","Cell RNA - HMC-1 [nTPM]":"46.6","Cell RNA - HSkMC [nTPM]":"25.6","Cell RNA - hTCEpi [nTPM]":"77.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"41.9","Cell RNA - hTERT-HME1 [nTPM]":"39.0","Cell RNA - hTERT-RPE1 [nTPM]":"62.2","Cell RNA - HUVEC TERT2 [nTPM]":"68.4","Cell RNA - JURKAT [nTPM]":"27.8","Cell RNA - K-562 [nTPM]":"39.6","Cell RNA - Karpas-707 [nTPM]":"51.6","Cell RNA - LHCN-M2 [nTPM]":"28.5","Cell RNA - MCF7 [nTPM]":"58.8","Cell RNA - MOLT-4 [nTPM]":"32.3","Cell RNA - NB-4 [nTPM]":"62.0","Cell RNA - NTERA-2 [nTPM]":"42.6","Cell RNA - OE19 [nTPM]":"64.1","Cell RNA - PC-3 [nTPM]":"22.5","Cell RNA - REH [nTPM]":"35.5","Cell RNA - RH-30 [nTPM]":"57.4","Cell RNA - RPMI-8226 [nTPM]":"74.1","Cell RNA - RPTEC TERT1 [nTPM]":"38.0","Cell RNA - RT4 [nTPM]":"19.5","Cell RNA - SCLC-21H [nTPM]":"19.7","Cell RNA - SH-SY5Y [nTPM]":"29.2","Cell RNA - SiHa [nTPM]":"15.5","Cell RNA - SK-BR-3 [nTPM]":"84.8","Cell RNA - SK-MEL-30 [nTPM]":"62.7","Cell RNA - SuSa [nTPM]":"21.8","Cell RNA - T-47d [nTPM]":"38.7","Cell RNA - THP-1 [nTPM]":"34.3","Cell RNA - TIME [nTPM]":"40.1","Cell RNA - U-138 MG [nTPM]":"26.5","Cell RNA - U-2 OS [nTPM]":"49.7","Cell RNA - U-2197 [nTPM]":"36.3","Cell RNA - U-251 MG [nTPM]":"56.5","Cell RNA - U-266\/70 [nTPM]":"66.5","Cell RNA - U-266\/84 [nTPM]":"36.5","Cell RNA - U-698 [nTPM]":"22.7","Cell RNA - U-87 MG [nTPM]":"46.9","Cell RNA - U-937 [nTPM]":"49.3","Cell RNA - WM-115 [nTPM]":"39.0","Blood RNA - basophil [nTPM]":"6.7","Blood RNA - classical monocyte [nTPM]":"2.4","Blood RNA - eosinophil [nTPM]":"1.9","Blood RNA - gdT-cell [nTPM]":"2.6","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"3.3","Blood RNA - memory B-cell [nTPM]":"1.2","Blood RNA - memory CD4 T-cell [nTPM]":"2.3","Blood RNA - memory CD8 T-cell [nTPM]":"2.5","Blood RNA - myeloid DC [nTPM]":"2.1","Blood RNA - naive B-cell [nTPM]":"1.9","Blood RNA - naive CD4 T-cell [nTPM]":"1.4","Blood RNA - naive CD8 T-cell [nTPM]":"1.6","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"8.4","Blood RNA - non-classical monocyte [nTPM]":"3.3","Blood RNA - plasmacytoid DC [nTPM]":"2.1","Blood RNA - T-reg [nTPM]":"3.3","Blood RNA - total PBMC [nTPM]":"1.7","Brain RNA - amygdala [nTPM]":"8.1","Brain RNA - basal ganglia [nTPM]":"9.1","Brain RNA - cerebellum [nTPM]":"9.0","Brain RNA - cerebral cortex [nTPM]":"13.3","Brain RNA - hippocampal formation [nTPM]":"8.3","Brain RNA - hypothalamus [nTPM]":"9.0","Brain RNA - medulla oblongata [nTPM]":"9.4","Brain RNA - midbrain [nTPM]":"8.7","Brain RNA - pons [nTPM]":"9.9","Brain RNA - spinal cord [nTPM]":"9.3","Brain RNA - thalamus [nTPM]":"8.9","Brain RNA - white matter [nTPM]":"9.8","Single Cell Type RNA - Adipocytes [nTPM]":"13.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.9","Single Cell Type RNA - Astrocytes [nTPM]":"16.3","Single Cell Type RNA - B-cells [nTPM]":"22.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"20.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.2","Single Cell Type RNA - Bipolar cells [nTPM]":"14.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"21.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"39.5","Single Cell Type RNA - dendritic cells [nTPM]":"34.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"21.9","Single Cell Type RNA - Early spermatids [nTPM]":"65.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.2","Single Cell Type RNA - Endothelial cells [nTPM]":"13.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.9","Single Cell Type RNA - Erythroid cells [nTPM]":"16.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"50.5","Single Cell Type RNA - Fibroblasts [nTPM]":"12.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"40.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.4","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"20.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.9","Single Cell Type RNA - Hepatocytes [nTPM]":"25.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.9","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"25.7","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"12.9","Single Cell Type RNA - Langerhans cells [nTPM]":"14.8","Single Cell Type RNA - Late spermatids [nTPM]":"222.0","Single Cell Type RNA - Leydig cells [nTPM]":"15.2","Single Cell Type RNA - Macrophages [nTPM]":"17.9","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"25.5","Single Cell Type RNA - Muller glia cells [nTPM]":"7.0","Single Cell Type RNA - NK-cells [nTPM]":"30.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.3","Single Cell Type RNA - Paneth cells [nTPM]":"19.7","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"43.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"22.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"37.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.7","Single Cell Type RNA - Spermatocytes [nTPM]":"13.0","Single Cell Type RNA - Spermatogonia [nTPM]":"5.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"52.0","Single Cell Type RNA - T-cells [nTPM]":"21.2","Single Cell Type RNA - Theca cells [nTPM]":"16.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.3","Single Cell Type RNA - Urothelial cells [nTPM]":"19.6"},{"Gene":"MPC1","Gene synonym":["BRP44L","CGI-129","dJ68L15.3","SLC54A1"],"Ensembl":"ENSG00000060762","Gene description":"Mitochondrial pyruvate carrier 1","Uniprot":["Q9Y5U8"],"Chromosome":"6","Position":"166364919-166383013","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"739.7","tongue":"559.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"950.0","Distal tubular cells":"1721.8","Proximal tubular cells":"573.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045119","HPA055790"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA045119":"AB_10960421","HPA055790":"AB_2682923"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.45e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.29e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.79e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-2"},"Tissue RNA - adipose tissue [nTPM]":"61.7","Tissue RNA - adrenal gland [nTPM]":"39.6","Tissue RNA - amygdala [nTPM]":"105.9","Tissue RNA - appendix [nTPM]":"33.4","Tissue RNA - basal ganglia [nTPM]":"119.5","Tissue RNA - bone marrow [nTPM]":"57.0","Tissue RNA - breast [nTPM]":"52.8","Tissue RNA - cerebellum [nTPM]":"129.7","Tissue RNA - cerebral cortex [nTPM]":"153.1","Tissue RNA - cervix [nTPM]":"52.4","Tissue RNA - choroid plexus [nTPM]":"108.0","Tissue RNA - colon [nTPM]":"97.7","Tissue RNA - duodenum [nTPM]":"84.8","Tissue RNA - endometrium 1 [nTPM]":"35.7","Tissue RNA - epididymis [nTPM]":"44.8","Tissue RNA - esophagus [nTPM]":"71.5","Tissue RNA - fallopian tube [nTPM]":"34.7","Tissue RNA - gallbladder [nTPM]":"41.7","Tissue RNA - heart muscle [nTPM]":"739.7","Tissue RNA - hippocampal formation [nTPM]":"101.2","Tissue RNA - hypothalamus [nTPM]":"127.8","Tissue RNA - kidney [nTPM]":"259.9","Tissue RNA - liver [nTPM]":"411.2","Tissue RNA - lung [nTPM]":"44.6","Tissue RNA - lymph node [nTPM]":"44.3","Tissue RNA - medulla oblongata [nTPM]":"119.2","Tissue RNA - midbrain [nTPM]":"123.9","Tissue RNA - ovary [nTPM]":"43.4","Tissue RNA - pancreas [nTPM]":"66.0","Tissue RNA - parathyroid gland [nTPM]":"141.8","Tissue RNA - pituitary gland [nTPM]":"38.1","Tissue RNA - placenta [nTPM]":"23.7","Tissue RNA - pons [nTPM]":"119.5","Tissue RNA - prostate [nTPM]":"43.5","Tissue RNA - rectum [nTPM]":"89.9","Tissue RNA - retina [nTPM]":"57.3","Tissue RNA - salivary gland [nTPM]":"87.7","Tissue RNA - seminal vesicle [nTPM]":"42.3","Tissue RNA - skeletal muscle [nTPM]":"319.4","Tissue RNA - skin 1 [nTPM]":"40.9","Tissue RNA - small intestine [nTPM]":"63.8","Tissue RNA - smooth muscle [nTPM]":"38.5","Tissue RNA - spinal cord [nTPM]":"117.1","Tissue RNA - spleen [nTPM]":"35.0","Tissue RNA - stomach 1 [nTPM]":"96.1","Tissue RNA - testis [nTPM]":"22.2","Tissue RNA - thalamus [nTPM]":"121.5","Tissue RNA - thymus [nTPM]":"48.6","Tissue RNA - thyroid gland [nTPM]":"82.9","Tissue RNA - tongue [nTPM]":"559.2","Tissue RNA - tonsil [nTPM]":"44.2","Tissue RNA - urinary bladder [nTPM]":"47.4","Tissue RNA - vagina [nTPM]":"34.9","Tissue RNA - white matter [nTPM]":"132.4","Cell RNA - A-431 [nTPM]":"25.6","Cell RNA - A549 [nTPM]":"7.5","Cell RNA - AF22 [nTPM]":"31.3","Cell RNA - AN3-CA [nTPM]":"107.7","Cell RNA - ASC diff [nTPM]":"88.4","Cell RNA - ASC TERT1 [nTPM]":"49.8","Cell RNA - BEWO [nTPM]":"45.2","Cell RNA - BJ [nTPM]":"29.1","Cell RNA - BJ hTERT+ [nTPM]":"47.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"45.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"43.9","Cell RNA - CACO-2 [nTPM]":"38.8","Cell RNA - CAPAN-2 [nTPM]":"17.9","Cell RNA - Daudi [nTPM]":"53.6","Cell RNA - EFO-21 [nTPM]":"50.9","Cell RNA - fHDF\/TERT166 [nTPM]":"45.4","Cell RNA - GAMG [nTPM]":"36.1","Cell RNA - HaCaT [nTPM]":"24.5","Cell RNA - HAP1 [nTPM]":"47.0","Cell RNA - HBEC3-KT [nTPM]":"36.7","Cell RNA - HBF TERT88 [nTPM]":"31.9","Cell RNA - HDLM-2 [nTPM]":"36.1","Cell RNA - HEK 293 [nTPM]":"79.0","Cell RNA - HEL [nTPM]":"27.5","Cell RNA - HeLa [nTPM]":"35.4","Cell RNA - Hep G2 [nTPM]":"132.6","Cell RNA - HHSteC [nTPM]":"36.6","Cell RNA - HL-60 [nTPM]":"104.9","Cell RNA - HMC-1 [nTPM]":"34.1","Cell RNA - HSkMC [nTPM]":"40.0","Cell RNA - hTCEpi [nTPM]":"51.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"36.8","Cell RNA - hTERT-HME1 [nTPM]":"26.7","Cell RNA - hTERT-RPE1 [nTPM]":"13.7","Cell RNA - HUVEC TERT2 [nTPM]":"36.9","Cell RNA - JURKAT [nTPM]":"80.8","Cell RNA - K-562 [nTPM]":"94.2","Cell RNA - Karpas-707 [nTPM]":"84.1","Cell RNA - LHCN-M2 [nTPM]":"28.6","Cell RNA - MCF7 [nTPM]":"40.5","Cell RNA - MOLT-4 [nTPM]":"73.1","Cell RNA - NB-4 [nTPM]":"193.7","Cell RNA - NTERA-2 [nTPM]":"16.1","Cell RNA - OE19 [nTPM]":"148.0","Cell RNA - PC-3 [nTPM]":"35.5","Cell RNA - REH [nTPM]":"39.1","Cell RNA - RH-30 [nTPM]":"51.7","Cell RNA - RPMI-8226 [nTPM]":"134.9","Cell RNA - RPTEC TERT1 [nTPM]":"85.4","Cell RNA - RT4 [nTPM]":"20.5","Cell RNA - SCLC-21H [nTPM]":"96.7","Cell RNA - SH-SY5Y [nTPM]":"85.7","Cell RNA - SiHa [nTPM]":"33.6","Cell RNA - SK-BR-3 [nTPM]":"145.8","Cell RNA - SK-MEL-30 [nTPM]":"34.0","Cell RNA - SuSa [nTPM]":"25.9","Cell RNA - T-47d [nTPM]":"34.5","Cell RNA - THP-1 [nTPM]":"154.3","Cell RNA - TIME [nTPM]":"25.3","Cell RNA - U-138 MG [nTPM]":"25.7","Cell RNA - U-2 OS [nTPM]":"26.8","Cell RNA - U-2197 [nTPM]":"91.6","Cell RNA - U-251 MG [nTPM]":"30.0","Cell RNA - U-266\/70 [nTPM]":"55.8","Cell RNA - U-266\/84 [nTPM]":"42.2","Cell RNA - U-698 [nTPM]":"46.3","Cell RNA - U-87 MG [nTPM]":"23.5","Cell RNA - U-937 [nTPM]":"127.0","Cell RNA - WM-115 [nTPM]":"42.1","Blood RNA - basophil [nTPM]":"60.7","Blood RNA - classical monocyte [nTPM]":"60.0","Blood RNA - eosinophil [nTPM]":"90.1","Blood RNA - gdT-cell [nTPM]":"41.7","Blood RNA - intermediate monocyte [nTPM]":"98.3","Blood RNA - MAIT T-cell [nTPM]":"39.4","Blood RNA - memory B-cell [nTPM]":"33.1","Blood RNA - memory CD4 T-cell [nTPM]":"48.5","Blood RNA - memory CD8 T-cell [nTPM]":"45.1","Blood RNA - myeloid DC [nTPM]":"72.2","Blood RNA - naive B-cell [nTPM]":"25.4","Blood RNA - naive CD4 T-cell [nTPM]":"44.7","Blood RNA - naive CD8 T-cell [nTPM]":"43.3","Blood RNA - neutrophil [nTPM]":"54.6","Blood RNA - NK-cell [nTPM]":"40.5","Blood RNA - non-classical monocyte [nTPM]":"128.5","Blood RNA - plasmacytoid DC [nTPM]":"43.0","Blood RNA - T-reg [nTPM]":"69.1","Blood RNA - total PBMC [nTPM]":"49.8","Brain RNA - amygdala [nTPM]":"105.9","Brain RNA - basal ganglia [nTPM]":"119.5","Brain RNA - cerebellum [nTPM]":"129.7","Brain RNA - cerebral cortex [nTPM]":"153.1","Brain RNA - hippocampal formation [nTPM]":"101.2","Brain RNA - hypothalamus [nTPM]":"127.8","Brain RNA - medulla oblongata [nTPM]":"119.2","Brain RNA - midbrain [nTPM]":"123.9","Brain RNA - pons [nTPM]":"119.5","Brain RNA - spinal cord [nTPM]":"117.1","Brain RNA - thalamus [nTPM]":"121.5","Brain RNA - white matter [nTPM]":"132.4","Single Cell Type RNA - Adipocytes [nTPM]":"56.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"118.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"48.0","Single Cell Type RNA - Astrocytes [nTPM]":"64.6","Single Cell Type RNA - B-cells [nTPM]":"51.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"45.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"44.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"83.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"29.0","Single Cell Type RNA - Bipolar cells [nTPM]":"61.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"74.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"79.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"950.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"187.3","Single Cell Type RNA - Club cells [nTPM]":"67.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"106.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"22.0","Single Cell Type RNA - dendritic cells [nTPM]":"54.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"219.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1721.8","Single Cell Type RNA - Ductal cells [nTPM]":"89.3","Single Cell Type RNA - Early spermatids [nTPM]":"66.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"73.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"50.7","Single Cell Type RNA - Endothelial cells [nTPM]":"51.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"37.2","Single Cell Type RNA - Erythroid cells [nTPM]":"72.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"49.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"140.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"78.3","Single Cell Type RNA - Fibroblasts [nTPM]":"74.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"63.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"93.2","Single Cell Type RNA - granulocytes [nTPM]":"71.0","Single Cell Type RNA - Granulosa cells [nTPM]":"28.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"47.5","Single Cell Type RNA - Hepatocytes [nTPM]":"391.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"121.4","Single Cell Type RNA - Horizontal cells [nTPM]":"48.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"74.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"122.1","Single Cell Type RNA - Ionocytes [nTPM]":"166.8","Single Cell Type RNA - Kupffer cells [nTPM]":"89.6","Single Cell Type RNA - Langerhans cells [nTPM]":"81.7","Single Cell Type RNA - Late spermatids [nTPM]":"10.2","Single Cell Type RNA - Leydig cells [nTPM]":"66.5","Single Cell Type RNA - Macrophages [nTPM]":"80.3","Single Cell Type RNA - Melanocytes [nTPM]":"129.9","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"104.7","Single Cell Type RNA - Muller glia cells [nTPM]":"199.9","Single Cell Type RNA - NK-cells [nTPM]":"58.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"32.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"108.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"65.2","Single Cell Type RNA - Paneth cells [nTPM]":"125.0","Single Cell Type RNA - Peritubular cells [nTPM]":"89.9","Single Cell Type RNA - Plasma cells [nTPM]":"114.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"32.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"162.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"573.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"46.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"66.7","Single Cell Type RNA - Sertoli cells [nTPM]":"92.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"76.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"80.4","Single Cell Type RNA - Spermatocytes [nTPM]":"163.2","Single Cell Type RNA - Spermatogonia [nTPM]":"79.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"67.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"55.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"24.4","Single Cell Type RNA - T-cells [nTPM]":"58.4","Single Cell Type RNA - Theca cells [nTPM]":"39.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"146.7","Single Cell Type RNA - Urothelial cells [nTPM]":"53.6"},{"Gene":"MPI","Gene synonym":[],"Ensembl":"ENSG00000178802","Gene description":"Mannose phosphate isomerase","Uniprot":["P34949"],"Chromosome":"15","Position":"74890005-74902219","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Isomerase"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"70.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007200"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"350000","Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA007200":"AB_1854079"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.39e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Tissue RNA - adipose tissue [nTPM]":"18.9","Tissue RNA - adrenal gland [nTPM]":"50.5","Tissue RNA - amygdala [nTPM]":"45.4","Tissue RNA - appendix [nTPM]":"16.7","Tissue RNA - basal ganglia [nTPM]":"47.3","Tissue RNA - bone marrow [nTPM]":"11.7","Tissue RNA - breast [nTPM]":"20.1","Tissue RNA - cerebellum [nTPM]":"52.2","Tissue RNA - cerebral cortex [nTPM]":"49.2","Tissue RNA - cervix [nTPM]":"23.9","Tissue RNA - choroid plexus [nTPM]":"41.1","Tissue RNA - colon [nTPM]":"31.8","Tissue RNA - duodenum [nTPM]":"45.6","Tissue RNA - endometrium 1 [nTPM]":"23.6","Tissue RNA - epididymis [nTPM]":"35.3","Tissue RNA - esophagus [nTPM]":"27.7","Tissue RNA - fallopian tube [nTPM]":"27.8","Tissue RNA - gallbladder [nTPM]":"16.0","Tissue RNA - heart muscle [nTPM]":"44.8","Tissue RNA - hippocampal formation [nTPM]":"46.6","Tissue RNA - hypothalamus [nTPM]":"47.9","Tissue RNA - kidney [nTPM]":"31.2","Tissue RNA - liver [nTPM]":"39.1","Tissue RNA - lung [nTPM]":"14.9","Tissue RNA - lymph node [nTPM]":"20.9","Tissue RNA - medulla oblongata [nTPM]":"55.5","Tissue RNA - midbrain [nTPM]":"50.1","Tissue RNA - ovary [nTPM]":"30.6","Tissue RNA - pancreas [nTPM]":"31.8","Tissue RNA - parathyroid gland [nTPM]":"31.1","Tissue RNA - pituitary gland [nTPM]":"22.9","Tissue RNA - placenta [nTPM]":"16.2","Tissue RNA - pons [nTPM]":"56.2","Tissue RNA - prostate [nTPM]":"27.5","Tissue RNA - rectum [nTPM]":"31.4","Tissue RNA - retina [nTPM]":"33.6","Tissue RNA - salivary gland [nTPM]":"23.7","Tissue RNA - seminal vesicle [nTPM]":"22.9","Tissue RNA - skeletal muscle [nTPM]":"52.2","Tissue RNA - skin 1 [nTPM]":"16.5","Tissue RNA - small intestine [nTPM]":"33.0","Tissue RNA - smooth muscle [nTPM]":"22.5","Tissue RNA - spinal cord [nTPM]":"45.7","Tissue RNA - spleen [nTPM]":"23.0","Tissue RNA - stomach 1 [nTPM]":"20.9","Tissue RNA - testis [nTPM]":"26.2","Tissue RNA - thalamus [nTPM]":"50.0","Tissue RNA - thymus [nTPM]":"23.2","Tissue RNA - thyroid gland [nTPM]":"23.2","Tissue RNA - tongue [nTPM]":"70.9","Tissue RNA - tonsil [nTPM]":"24.2","Tissue RNA - urinary bladder [nTPM]":"24.2","Tissue RNA - vagina [nTPM]":"19.5","Tissue RNA - white matter [nTPM]":"47.1","Cell RNA - A-431 [nTPM]":"27.2","Cell RNA - A549 [nTPM]":"36.9","Cell RNA - AF22 [nTPM]":"29.8","Cell RNA - AN3-CA [nTPM]":"34.0","Cell RNA - ASC diff [nTPM]":"66.7","Cell RNA - ASC TERT1 [nTPM]":"32.2","Cell RNA - BEWO [nTPM]":"26.0","Cell RNA - BJ [nTPM]":"22.8","Cell RNA - BJ hTERT+ [nTPM]":"37.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"38.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"53.4","Cell RNA - CACO-2 [nTPM]":"36.7","Cell RNA - CAPAN-2 [nTPM]":"35.0","Cell RNA - Daudi [nTPM]":"38.3","Cell RNA - EFO-21 [nTPM]":"48.6","Cell RNA - fHDF\/TERT166 [nTPM]":"33.6","Cell RNA - GAMG [nTPM]":"30.6","Cell RNA - HaCaT [nTPM]":"65.9","Cell RNA - HAP1 [nTPM]":"60.0","Cell RNA - HBEC3-KT [nTPM]":"66.7","Cell RNA - HBF TERT88 [nTPM]":"36.2","Cell RNA - HDLM-2 [nTPM]":"29.4","Cell RNA - HEK 293 [nTPM]":"74.9","Cell RNA - HEL [nTPM]":"68.8","Cell RNA - HeLa [nTPM]":"35.3","Cell RNA - Hep G2 [nTPM]":"39.9","Cell RNA - HHSteC [nTPM]":"47.5","Cell RNA - HL-60 [nTPM]":"32.0","Cell RNA - HMC-1 [nTPM]":"19.4","Cell RNA - HSkMC [nTPM]":"43.1","Cell RNA - hTCEpi [nTPM]":"16.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"36.2","Cell RNA - hTERT-HME1 [nTPM]":"64.4","Cell RNA - hTERT-RPE1 [nTPM]":"58.1","Cell RNA - HUVEC TERT2 [nTPM]":"52.9","Cell RNA - JURKAT [nTPM]":"45.2","Cell RNA - K-562 [nTPM]":"23.4","Cell RNA - Karpas-707 [nTPM]":"30.7","Cell RNA - LHCN-M2 [nTPM]":"50.1","Cell RNA - MCF7 [nTPM]":"23.2","Cell RNA - MOLT-4 [nTPM]":"34.6","Cell RNA - NB-4 [nTPM]":"14.2","Cell RNA - NTERA-2 [nTPM]":"16.4","Cell RNA - OE19 [nTPM]":"40.9","Cell RNA - PC-3 [nTPM]":"31.0","Cell RNA - REH [nTPM]":"35.0","Cell RNA - RH-30 [nTPM]":"28.0","Cell RNA - RPMI-8226 [nTPM]":"94.9","Cell RNA - RPTEC TERT1 [nTPM]":"45.5","Cell RNA - RT4 [nTPM]":"30.4","Cell RNA - SCLC-21H [nTPM]":"55.7","Cell RNA - SH-SY5Y [nTPM]":"24.4","Cell RNA - SiHa [nTPM]":"26.7","Cell RNA - SK-BR-3 [nTPM]":"47.5","Cell RNA - SK-MEL-30 [nTPM]":"28.7","Cell RNA - SuSa [nTPM]":"43.5","Cell RNA - T-47d [nTPM]":"65.3","Cell RNA - THP-1 [nTPM]":"21.9","Cell RNA - TIME [nTPM]":"24.1","Cell RNA - U-138 MG [nTPM]":"22.9","Cell RNA - U-2 OS [nTPM]":"19.4","Cell RNA - U-2197 [nTPM]":"17.3","Cell RNA - U-251 MG [nTPM]":"22.6","Cell RNA - U-266\/70 [nTPM]":"75.0","Cell RNA - U-266\/84 [nTPM]":"48.4","Cell RNA - U-698 [nTPM]":"25.1","Cell RNA - U-87 MG [nTPM]":"47.9","Cell RNA - U-937 [nTPM]":"45.8","Cell RNA - WM-115 [nTPM]":"17.1","Blood RNA - basophil [nTPM]":"2.3","Blood RNA - classical monocyte [nTPM]":"16.2","Blood RNA - eosinophil [nTPM]":"5.7","Blood RNA - gdT-cell [nTPM]":"28.2","Blood RNA - intermediate monocyte [nTPM]":"17.0","Blood RNA - MAIT T-cell [nTPM]":"37.0","Blood RNA - memory B-cell [nTPM]":"27.4","Blood RNA - memory CD4 T-cell [nTPM]":"38.3","Blood RNA - memory CD8 T-cell [nTPM]":"32.6","Blood RNA - myeloid DC [nTPM]":"23.0","Blood RNA - naive B-cell [nTPM]":"31.9","Blood RNA - naive CD4 T-cell [nTPM]":"56.0","Blood RNA - naive CD8 T-cell [nTPM]":"40.8","Blood RNA - neutrophil [nTPM]":"2.7","Blood RNA - NK-cell [nTPM]":"43.1","Blood RNA - non-classical monocyte [nTPM]":"15.5","Blood RNA - plasmacytoid DC [nTPM]":"19.1","Blood RNA - T-reg [nTPM]":"53.1","Blood RNA - total PBMC [nTPM]":"29.0","Brain RNA - amygdala [nTPM]":"45.4","Brain RNA - basal ganglia [nTPM]":"47.3","Brain RNA - cerebellum [nTPM]":"52.2","Brain RNA - cerebral cortex [nTPM]":"49.2","Brain RNA - hippocampal formation [nTPM]":"46.6","Brain RNA - hypothalamus [nTPM]":"47.9","Brain RNA - medulla oblongata [nTPM]":"55.5","Brain RNA - midbrain [nTPM]":"50.1","Brain RNA - pons [nTPM]":"56.2","Brain RNA - spinal cord [nTPM]":"45.7","Brain RNA - thalamus [nTPM]":"50.0","Brain RNA - white matter [nTPM]":"47.1","Single Cell Type RNA - Adipocytes [nTPM]":"5.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.0","Single Cell Type RNA - Astrocytes [nTPM]":"7.8","Single Cell Type RNA - B-cells [nTPM]":"10.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"23.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"54.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"10.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"31.8","Single Cell Type RNA - dendritic cells [nTPM]":"9.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"28.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"19.6","Single Cell Type RNA - Early spermatids [nTPM]":"18.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.2","Single Cell Type RNA - Endothelial cells [nTPM]":"9.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.8","Single Cell Type RNA - Erythroid cells [nTPM]":"4.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.4","Single Cell Type RNA - Fibroblasts [nTPM]":"10.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.5","Single Cell Type RNA - granulocytes [nTPM]":"15.2","Single Cell Type RNA - Granulosa cells [nTPM]":"13.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"18.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.9","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.0","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"7.2","Single Cell Type RNA - Langerhans cells [nTPM]":"2.2","Single Cell Type RNA - Late spermatids [nTPM]":"31.3","Single Cell Type RNA - Leydig cells [nTPM]":"11.1","Single Cell Type RNA - Macrophages [nTPM]":"6.6","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"9.7","Single Cell Type RNA - Muller glia cells [nTPM]":"20.7","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.2","Single Cell Type RNA - Paneth cells [nTPM]":"33.2","Single Cell Type RNA - Peritubular cells [nTPM]":"8.6","Single Cell Type RNA - Plasma cells [nTPM]":"11.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"70.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"31.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.1","Single Cell Type RNA - Spermatocytes [nTPM]":"34.5","Single Cell Type RNA - Spermatogonia [nTPM]":"9.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.3","Single Cell Type RNA - T-cells [nTPM]":"11.1","Single Cell Type RNA - Theca cells [nTPM]":"21.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.4","Single Cell Type RNA - Urothelial cells [nTPM]":"6.2"},{"Gene":"MPO","Gene synonym":[],"Ensembl":"ENSG00000005381","Gene description":"Myeloperoxidase","Uniprot":["P05164"],"Chromosome":"17","Position":"58269855-58280935","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Hydrogen peroxide"],"Molecular function":["Oxidoreductase","Peroxidase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"61","RNA tissue specific nTPM":{"bone marrow":"4023.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"30","RNA single cell type specific nTPM":{"Erythroid cells":"87.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"stomach cancer":"1.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"6.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"94","RNA cell line specific nTPM":{"HL-60":"3517.4","NB-4":"4589.9"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000059","HPA021147","HPA061464"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":576000000,"Blood concentration - Conc. blood MS [pg\/L]":"24000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB000059":"AB_2335676","HPA021147":"AB_1854083","HPA061464":"AB_2684531"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"0.4","Tissue RNA - amygdala [nTPM]":"0.8","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"4023.1","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"1.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"1.1","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"1.1","Tissue RNA - hippocampal formation [nTPM]":"0.8","Tissue RNA - hypothalamus [nTPM]":"0.7","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"1.8","Tissue RNA - lung [nTPM]":"8.4","Tissue RNA - lymph node [nTPM]":"1.7","Tissue RNA - medulla oblongata [nTPM]":"0.9","Tissue RNA - midbrain [nTPM]":"1.0","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.5","Tissue RNA - placenta [nTPM]":"1.4","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"66.3","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"1.1","Tissue RNA - skin 1 [nTPM]":"4.3","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"21.7","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"0.8","Tissue RNA - thymus [nTPM]":"10.9","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.5","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.7","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"1.7","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"3517.4","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"4589.9","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"5.3","Cell RNA - RH-30 [nTPM]":"3.2","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"1.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"43.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"1.3","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"1.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"4.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"6.2","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"3.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"2.4","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"1.4","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"7.5","Brain RNA - amygdala [nTPM]":"0.8","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"1.1","Brain RNA - hippocampal formation [nTPM]":"0.8","Brain RNA - hypothalamus [nTPM]":"0.7","Brain RNA - medulla oblongata [nTPM]":"0.9","Brain RNA - midbrain [nTPM]":"1.0","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"0.8","Brain RNA - white matter [nTPM]":"0.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"87.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.9","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.2","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"2.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"2.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"MPST","Gene synonym":["MST","TST2","TUM1"],"Ensembl":"ENSG00000128309","Gene description":"Mercaptopyruvate sulfurtransferase","Uniprot":["P25325"],"Chromosome":"22","Position":"37019635-37029821","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"390.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"553.6","Hepatocytes":"578.6","Paneth cells":"621.4","Proximal enterocytes":"1322.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001240"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2900000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA001240":"AB_1079408"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.18e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.89e-4"},"Tissue RNA - adipose tissue [nTPM]":"58.0","Tissue RNA - adrenal gland [nTPM]":"57.3","Tissue RNA - amygdala [nTPM]":"25.3","Tissue RNA - appendix [nTPM]":"10.0","Tissue RNA - basal ganglia [nTPM]":"32.3","Tissue RNA - bone marrow [nTPM]":"36.5","Tissue RNA - breast [nTPM]":"51.0","Tissue RNA - cerebellum [nTPM]":"29.0","Tissue RNA - cerebral cortex [nTPM]":"31.0","Tissue RNA - cervix [nTPM]":"40.9","Tissue RNA - choroid plexus [nTPM]":"29.8","Tissue RNA - colon [nTPM]":"102.4","Tissue RNA - duodenum [nTPM]":"106.5","Tissue RNA - endometrium 1 [nTPM]":"34.7","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"91.5","Tissue RNA - fallopian tube [nTPM]":"42.9","Tissue RNA - gallbladder [nTPM]":"16.6","Tissue RNA - heart muscle [nTPM]":"64.2","Tissue RNA - hippocampal formation [nTPM]":"22.9","Tissue RNA - hypothalamus [nTPM]":"23.4","Tissue RNA - kidney [nTPM]":"71.4","Tissue RNA - liver [nTPM]":"390.7","Tissue RNA - lung [nTPM]":"43.5","Tissue RNA - lymph node [nTPM]":"8.8","Tissue RNA - medulla oblongata [nTPM]":"34.0","Tissue RNA - midbrain [nTPM]":"27.5","Tissue RNA - ovary [nTPM]":"81.7","Tissue RNA - pancreas [nTPM]":"106.4","Tissue RNA - parathyroid gland [nTPM]":"4.8","Tissue RNA - pituitary gland [nTPM]":"14.7","Tissue RNA - placenta [nTPM]":"9.1","Tissue RNA - pons [nTPM]":"29.7","Tissue RNA - prostate [nTPM]":"45.3","Tissue RNA - rectum [nTPM]":"17.0","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"43.5","Tissue RNA - seminal vesicle [nTPM]":"9.6","Tissue RNA - skeletal muscle [nTPM]":"89.7","Tissue RNA - skin 1 [nTPM]":"82.3","Tissue RNA - small intestine [nTPM]":"93.0","Tissue RNA - smooth muscle [nTPM]":"7.0","Tissue RNA - spinal cord [nTPM]":"26.0","Tissue RNA - spleen [nTPM]":"22.1","Tissue RNA - stomach 1 [nTPM]":"70.3","Tissue RNA - testis [nTPM]":"51.7","Tissue RNA - thalamus [nTPM]":"31.4","Tissue RNA - thymus [nTPM]":"4.5","Tissue RNA - thyroid gland [nTPM]":"24.8","Tissue RNA - tongue [nTPM]":"23.1","Tissue RNA - tonsil [nTPM]":"6.0","Tissue RNA - urinary bladder [nTPM]":"48.3","Tissue RNA - vagina [nTPM]":"62.3","Tissue RNA - white matter [nTPM]":"35.1","Cell RNA - A-431 [nTPM]":"44.0","Cell RNA - A549 [nTPM]":"50.4","Cell RNA - AF22 [nTPM]":"24.2","Cell RNA - AN3-CA [nTPM]":"50.0","Cell RNA - ASC diff [nTPM]":"27.8","Cell RNA - ASC TERT1 [nTPM]":"17.2","Cell RNA - BEWO [nTPM]":"38.1","Cell RNA - BJ [nTPM]":"23.4","Cell RNA - BJ hTERT+ [nTPM]":"20.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"33.2","Cell RNA - CACO-2 [nTPM]":"48.6","Cell RNA - CAPAN-2 [nTPM]":"18.9","Cell RNA - Daudi [nTPM]":"68.7","Cell RNA - EFO-21 [nTPM]":"33.0","Cell RNA - fHDF\/TERT166 [nTPM]":"16.7","Cell RNA - GAMG [nTPM]":"16.7","Cell RNA - HaCaT [nTPM]":"29.9","Cell RNA - HAP1 [nTPM]":"20.9","Cell RNA - HBEC3-KT [nTPM]":"33.8","Cell RNA - HBF TERT88 [nTPM]":"3.6","Cell RNA - HDLM-2 [nTPM]":"41.4","Cell RNA - HEK 293 [nTPM]":"119.2","Cell RNA - HEL [nTPM]":"26.5","Cell RNA - HeLa [nTPM]":"21.3","Cell RNA - Hep G2 [nTPM]":"115.6","Cell RNA - HHSteC [nTPM]":"87.5","Cell RNA - HL-60 [nTPM]":"29.0","Cell RNA - HMC-1 [nTPM]":"35.6","Cell RNA - HSkMC [nTPM]":"30.0","Cell RNA - hTCEpi [nTPM]":"64.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.1","Cell RNA - hTERT-HME1 [nTPM]":"15.1","Cell RNA - hTERT-RPE1 [nTPM]":"22.8","Cell RNA - HUVEC TERT2 [nTPM]":"50.6","Cell RNA - JURKAT [nTPM]":"33.1","Cell RNA - K-562 [nTPM]":"48.0","Cell RNA - Karpas-707 [nTPM]":"19.3","Cell RNA - LHCN-M2 [nTPM]":"7.0","Cell RNA - MCF7 [nTPM]":"33.8","Cell RNA - MOLT-4 [nTPM]":"2.6","Cell RNA - NB-4 [nTPM]":"97.5","Cell RNA - NTERA-2 [nTPM]":"45.7","Cell RNA - OE19 [nTPM]":"56.7","Cell RNA - PC-3 [nTPM]":"52.2","Cell RNA - REH [nTPM]":"73.6","Cell RNA - RH-30 [nTPM]":"28.8","Cell RNA - RPMI-8226 [nTPM]":"51.9","Cell RNA - RPTEC TERT1 [nTPM]":"25.5","Cell RNA - RT4 [nTPM]":"14.0","Cell RNA - SCLC-21H [nTPM]":"12.4","Cell RNA - SH-SY5Y [nTPM]":"92.9","Cell RNA - SiHa [nTPM]":"15.6","Cell RNA - SK-BR-3 [nTPM]":"23.9","Cell RNA - SK-MEL-30 [nTPM]":"46.6","Cell RNA - SuSa [nTPM]":"12.2","Cell RNA - T-47d [nTPM]":"26.0","Cell RNA - THP-1 [nTPM]":"45.6","Cell RNA - TIME [nTPM]":"39.8","Cell RNA - U-138 MG [nTPM]":"21.3","Cell RNA - U-2 OS [nTPM]":"60.1","Cell RNA - U-2197 [nTPM]":"23.9","Cell RNA - U-251 MG [nTPM]":"16.0","Cell RNA - U-266\/70 [nTPM]":"33.3","Cell RNA - U-266\/84 [nTPM]":"16.8","Cell RNA - U-698 [nTPM]":"21.0","Cell RNA - U-87 MG [nTPM]":"7.7","Cell RNA - U-937 [nTPM]":"34.7","Cell RNA - WM-115 [nTPM]":"11.1","Blood RNA - basophil [nTPM]":"48.5","Blood RNA - classical monocyte [nTPM]":"71.9","Blood RNA - eosinophil [nTPM]":"54.7","Blood RNA - gdT-cell [nTPM]":"31.0","Blood RNA - intermediate monocyte [nTPM]":"27.5","Blood RNA - MAIT T-cell [nTPM]":"42.4","Blood RNA - memory B-cell [nTPM]":"24.9","Blood RNA - memory CD4 T-cell [nTPM]":"20.1","Blood RNA - memory CD8 T-cell [nTPM]":"26.4","Blood RNA - myeloid DC [nTPM]":"104.0","Blood RNA - naive B-cell [nTPM]":"25.0","Blood RNA - naive CD4 T-cell [nTPM]":"2.7","Blood RNA - naive CD8 T-cell [nTPM]":"10.4","Blood RNA - neutrophil [nTPM]":"21.9","Blood RNA - NK-cell [nTPM]":"87.8","Blood RNA - non-classical monocyte [nTPM]":"12.7","Blood RNA - plasmacytoid DC [nTPM]":"16.3","Blood RNA - T-reg [nTPM]":"44.3","Blood RNA - total PBMC [nTPM]":"35.4","Brain RNA - amygdala [nTPM]":"25.3","Brain RNA - basal ganglia [nTPM]":"32.3","Brain RNA - cerebellum [nTPM]":"29.0","Brain RNA - cerebral cortex [nTPM]":"31.0","Brain RNA - hippocampal formation [nTPM]":"22.9","Brain RNA - hypothalamus [nTPM]":"23.4","Brain RNA - medulla oblongata [nTPM]":"34.0","Brain RNA - midbrain [nTPM]":"27.5","Brain RNA - pons [nTPM]":"29.7","Brain RNA - spinal cord [nTPM]":"26.0","Brain RNA - thalamus [nTPM]":"31.4","Brain RNA - white matter [nTPM]":"35.1","Single Cell Type RNA - Adipocytes [nTPM]":"21.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"61.9","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"25.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"81.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"80.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"120.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"70.6","Single Cell Type RNA - Bipolar cells [nTPM]":"4.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"81.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"83.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"29.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"243.1","Single Cell Type RNA - Club cells [nTPM]":"70.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"60.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"61.9","Single Cell Type RNA - dendritic cells [nTPM]":"20.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"553.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"133.1","Single Cell Type RNA - Ductal cells [nTPM]":"146.4","Single Cell Type RNA - Early spermatids [nTPM]":"191.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"38.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"46.8","Single Cell Type RNA - Endothelial cells [nTPM]":"42.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"108.6","Single Cell Type RNA - Erythroid cells [nTPM]":"122.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"148.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"119.1","Single Cell Type RNA - Fibroblasts [nTPM]":"52.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"87.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"72.5","Single Cell Type RNA - granulocytes [nTPM]":"17.2","Single Cell Type RNA - Granulosa cells [nTPM]":"140.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"108.5","Single Cell Type RNA - Hepatocytes [nTPM]":"578.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"77.5","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"363.1","Single Cell Type RNA - Ionocytes [nTPM]":"85.5","Single Cell Type RNA - Kupffer cells [nTPM]":"84.6","Single Cell Type RNA - Langerhans cells [nTPM]":"77.6","Single Cell Type RNA - Late spermatids [nTPM]":"115.1","Single Cell Type RNA - Leydig cells [nTPM]":"91.0","Single Cell Type RNA - Macrophages [nTPM]":"62.7","Single Cell Type RNA - Melanocytes [nTPM]":"58.7","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"60.7","Single Cell Type RNA - Muller glia cells [nTPM]":"24.8","Single Cell Type RNA - NK-cells [nTPM]":"56.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"117.9","Single Cell Type RNA - Paneth cells [nTPM]":"621.4","Single Cell Type RNA - Peritubular cells [nTPM]":"84.7","Single Cell Type RNA - Plasma cells [nTPM]":"65.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"77.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1322.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"469.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.8","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"34.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"36.0","Single Cell Type RNA - Spermatocytes [nTPM]":"101.3","Single Cell Type RNA - Spermatogonia [nTPM]":"11.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"133.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"152.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"50.1","Single Cell Type RNA - T-cells [nTPM]":"26.6","Single Cell Type RNA - Theca cells [nTPM]":"57.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"397.5","Single Cell Type RNA - Urothelial cells [nTPM]":"110.6"},{"Gene":"MPV17","Gene synonym":["SYM1"],"Ensembl":"ENSG00000115204","Gene description":"Mitochondrial inner membrane protein MPV17","Uniprot":["P39210"],"Chromosome":"2","Position":"27309492-27325680","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.99e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"},"Tissue RNA - adipose tissue [nTPM]":"50.2","Tissue RNA - adrenal gland [nTPM]":"86.5","Tissue RNA - amygdala [nTPM]":"56.4","Tissue RNA - appendix [nTPM]":"37.8","Tissue RNA - basal ganglia [nTPM]":"58.1","Tissue RNA - bone marrow [nTPM]":"31.3","Tissue RNA - breast [nTPM]":"39.9","Tissue RNA - cerebellum [nTPM]":"59.1","Tissue RNA - cerebral cortex [nTPM]":"58.4","Tissue RNA - cervix [nTPM]":"36.0","Tissue RNA - choroid plexus [nTPM]":"59.3","Tissue RNA - colon [nTPM]":"32.5","Tissue RNA - duodenum [nTPM]":"25.0","Tissue RNA - endometrium 1 [nTPM]":"37.9","Tissue RNA - epididymis [nTPM]":"47.7","Tissue RNA - esophagus [nTPM]":"32.6","Tissue RNA - fallopian tube [nTPM]":"37.7","Tissue RNA - gallbladder [nTPM]":"36.7","Tissue RNA - heart muscle [nTPM]":"78.2","Tissue RNA - hippocampal formation [nTPM]":"56.3","Tissue RNA - hypothalamus [nTPM]":"59.1","Tissue RNA - kidney [nTPM]":"48.6","Tissue RNA - liver [nTPM]":"22.6","Tissue RNA - lung [nTPM]":"39.1","Tissue RNA - lymph node [nTPM]":"43.2","Tissue RNA - medulla oblongata [nTPM]":"58.8","Tissue RNA - midbrain [nTPM]":"57.1","Tissue RNA - ovary [nTPM]":"43.7","Tissue RNA - pancreas [nTPM]":"33.2","Tissue RNA - parathyroid gland [nTPM]":"70.0","Tissue RNA - pituitary gland [nTPM]":"38.9","Tissue RNA - placenta [nTPM]":"35.0","Tissue RNA - pons [nTPM]":"58.1","Tissue RNA - prostate [nTPM]":"34.1","Tissue RNA - rectum [nTPM]":"34.1","Tissue RNA - retina [nTPM]":"26.7","Tissue RNA - salivary gland [nTPM]":"35.9","Tissue RNA - seminal vesicle [nTPM]":"35.0","Tissue RNA - skeletal muscle [nTPM]":"18.3","Tissue RNA - skin 1 [nTPM]":"32.0","Tissue RNA - small intestine [nTPM]":"27.5","Tissue RNA - smooth muscle [nTPM]":"57.7","Tissue RNA - spinal cord [nTPM]":"56.9","Tissue RNA - spleen [nTPM]":"37.1","Tissue RNA - stomach 1 [nTPM]":"29.1","Tissue RNA - testis [nTPM]":"15.5","Tissue RNA - thalamus [nTPM]":"60.3","Tissue RNA - thymus [nTPM]":"46.0","Tissue RNA - thyroid gland [nTPM]":"51.6","Tissue RNA - tongue [nTPM]":"30.0","Tissue RNA - tonsil [nTPM]":"48.1","Tissue RNA - urinary bladder [nTPM]":"44.9","Tissue RNA - vagina [nTPM]":"28.1","Tissue RNA - white matter [nTPM]":"63.2","Cell RNA - A-431 [nTPM]":"74.1","Cell RNA - A549 [nTPM]":"68.2","Cell RNA - AF22 [nTPM]":"49.7","Cell RNA - AN3-CA [nTPM]":"42.6","Cell RNA - ASC diff [nTPM]":"202.7","Cell RNA - ASC TERT1 [nTPM]":"237.0","Cell RNA - BEWO [nTPM]":"46.6","Cell RNA - BJ [nTPM]":"70.8","Cell RNA - BJ hTERT+ [nTPM]":"143.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"67.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"60.7","Cell RNA - CACO-2 [nTPM]":"55.0","Cell RNA - CAPAN-2 [nTPM]":"52.0","Cell RNA - Daudi [nTPM]":"41.5","Cell RNA - EFO-21 [nTPM]":"72.8","Cell RNA - fHDF\/TERT166 [nTPM]":"97.2","Cell RNA - GAMG [nTPM]":"124.0","Cell RNA - HaCaT [nTPM]":"61.3","Cell RNA - HAP1 [nTPM]":"64.1","Cell RNA - HBEC3-KT [nTPM]":"134.1","Cell RNA - HBF TERT88 [nTPM]":"69.5","Cell RNA - HDLM-2 [nTPM]":"56.9","Cell RNA - HEK 293 [nTPM]":"63.7","Cell RNA - HEL [nTPM]":"79.5","Cell RNA - HeLa [nTPM]":"58.8","Cell RNA - Hep G2 [nTPM]":"105.6","Cell RNA - HHSteC [nTPM]":"125.4","Cell RNA - HL-60 [nTPM]":"47.3","Cell RNA - HMC-1 [nTPM]":"48.7","Cell RNA - HSkMC [nTPM]":"229.3","Cell RNA - hTCEpi [nTPM]":"116.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"118.6","Cell RNA - hTERT-HME1 [nTPM]":"169.4","Cell RNA - hTERT-RPE1 [nTPM]":"94.3","Cell RNA - HUVEC TERT2 [nTPM]":"100.2","Cell RNA - JURKAT [nTPM]":"49.8","Cell RNA - K-562 [nTPM]":"77.0","Cell RNA - Karpas-707 [nTPM]":"77.1","Cell RNA - LHCN-M2 [nTPM]":"113.9","Cell RNA - MCF7 [nTPM]":"107.4","Cell RNA - MOLT-4 [nTPM]":"46.9","Cell RNA - NB-4 [nTPM]":"71.5","Cell RNA - NTERA-2 [nTPM]":"55.7","Cell RNA - OE19 [nTPM]":"106.7","Cell RNA - PC-3 [nTPM]":"69.1","Cell RNA - REH [nTPM]":"64.6","Cell RNA - RH-30 [nTPM]":"73.2","Cell RNA - RPMI-8226 [nTPM]":"85.2","Cell RNA - RPTEC TERT1 [nTPM]":"149.2","Cell RNA - RT4 [nTPM]":"58.5","Cell RNA - SCLC-21H [nTPM]":"33.1","Cell RNA - SH-SY5Y [nTPM]":"107.2","Cell RNA - SiHa [nTPM]":"37.6","Cell RNA - SK-BR-3 [nTPM]":"43.7","Cell RNA - SK-MEL-30 [nTPM]":"82.1","Cell RNA - SuSa [nTPM]":"49.3","Cell RNA - T-47d [nTPM]":"49.0","Cell RNA - THP-1 [nTPM]":"60.6","Cell RNA - TIME [nTPM]":"88.6","Cell RNA - U-138 MG [nTPM]":"67.0","Cell RNA - U-2 OS [nTPM]":"68.8","Cell RNA - U-2197 [nTPM]":"83.4","Cell RNA - U-251 MG [nTPM]":"76.4","Cell RNA - U-266\/70 [nTPM]":"108.1","Cell RNA - U-266\/84 [nTPM]":"106.1","Cell RNA - U-698 [nTPM]":"130.4","Cell RNA - U-87 MG [nTPM]":"109.2","Cell RNA - U-937 [nTPM]":"105.4","Cell RNA - WM-115 [nTPM]":"76.1","Blood RNA - basophil [nTPM]":"59.5","Blood RNA - classical monocyte [nTPM]":"93.7","Blood RNA - eosinophil [nTPM]":"42.9","Blood RNA - gdT-cell [nTPM]":"59.3","Blood RNA - intermediate monocyte [nTPM]":"81.4","Blood RNA - MAIT T-cell [nTPM]":"64.4","Blood RNA - memory B-cell [nTPM]":"84.5","Blood RNA - memory CD4 T-cell [nTPM]":"60.5","Blood RNA - memory CD8 T-cell [nTPM]":"67.4","Blood RNA - myeloid DC [nTPM]":"120.5","Blood RNA - naive B-cell [nTPM]":"73.6","Blood RNA - naive CD4 T-cell [nTPM]":"58.0","Blood RNA - naive CD8 T-cell [nTPM]":"67.8","Blood RNA - neutrophil [nTPM]":"7.8","Blood RNA - NK-cell [nTPM]":"76.0","Blood RNA - non-classical monocyte [nTPM]":"81.7","Blood RNA - plasmacytoid DC [nTPM]":"87.4","Blood RNA - T-reg [nTPM]":"81.4","Blood RNA - total PBMC [nTPM]":"92.1","Brain RNA - amygdala [nTPM]":"56.4","Brain RNA - basal ganglia [nTPM]":"58.1","Brain RNA - cerebellum [nTPM]":"59.1","Brain RNA - cerebral cortex [nTPM]":"58.4","Brain RNA - hippocampal formation [nTPM]":"56.3","Brain RNA - hypothalamus [nTPM]":"59.1","Brain RNA - medulla oblongata [nTPM]":"58.8","Brain RNA - midbrain [nTPM]":"57.1","Brain RNA - pons [nTPM]":"58.1","Brain RNA - spinal cord [nTPM]":"56.9","Brain RNA - thalamus [nTPM]":"60.3","Brain RNA - white matter [nTPM]":"63.2","Single Cell Type RNA - Adipocytes [nTPM]":"36.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.3","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"26.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"69.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"33.0","Single Cell Type RNA - Bipolar cells [nTPM]":"20.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"49.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"52.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"48.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"46.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"51.1","Single Cell Type RNA - dendritic cells [nTPM]":"26.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"64.6","Single Cell Type RNA - Ductal cells [nTPM]":"43.3","Single Cell Type RNA - Early spermatids [nTPM]":"27.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"32.6","Single Cell Type RNA - Endothelial cells [nTPM]":"35.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.8","Single Cell Type RNA - Erythroid cells [nTPM]":"21.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"24.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"60.2","Single Cell Type RNA - Fibroblasts [nTPM]":"37.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.5","Single Cell Type RNA - granulocytes [nTPM]":"42.5","Single Cell Type RNA - Granulosa cells [nTPM]":"28.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.2","Single Cell Type RNA - Hepatocytes [nTPM]":"9.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"116.9","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.0","Single Cell Type RNA - Ionocytes [nTPM]":"59.0","Single Cell Type RNA - Kupffer cells [nTPM]":"28.5","Single Cell Type RNA - Langerhans cells [nTPM]":"24.0","Single Cell Type RNA - Late spermatids [nTPM]":"34.2","Single Cell Type RNA - Leydig cells [nTPM]":"35.4","Single Cell Type RNA - Macrophages [nTPM]":"33.7","Single Cell Type RNA - Melanocytes [nTPM]":"40.9","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"38.1","Single Cell Type RNA - Muller glia cells [nTPM]":"38.9","Single Cell Type RNA - NK-cells [nTPM]":"28.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.7","Single Cell Type RNA - Paneth cells [nTPM]":"12.9","Single Cell Type RNA - Peritubular cells [nTPM]":"35.0","Single Cell Type RNA - Plasma cells [nTPM]":"31.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"32.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"87.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"36.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"30.8","Single Cell Type RNA - Spermatocytes [nTPM]":"15.5","Single Cell Type RNA - Spermatogonia [nTPM]":"21.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"33.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"59.4","Single Cell Type RNA - T-cells [nTPM]":"22.2","Single Cell Type RNA - Theca cells [nTPM]":"41.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.7","Single Cell Type RNA - Urothelial cells [nTPM]":"30.7"},{"Gene":"MRAS","Gene synonym":["M-RAs","R-RAS3","RRAS3"],"Ensembl":"ENSG00000158186","Gene description":"Muscle RAS oncogene homolog","Uniprot":["O14807"],"Chromosome":"3","Position":"138347648-138405534","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"202.3","heart muscle":"132.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"121.7","Distal tubular cells":"58.7","Theca cells":"59.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"non-classical monocyte":"25.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"monocytes":"25.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ":"92.9","EFO-21":"113.7","fHDF\/TERT166":"70.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042728"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA042728":"AB_10796582"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.73e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Tissue RNA - adipose tissue [nTPM]":"91.9","Tissue RNA - adrenal gland [nTPM]":"67.7","Tissue RNA - amygdala [nTPM]":"112.7","Tissue RNA - appendix [nTPM]":"10.8","Tissue RNA - basal ganglia [nTPM]":"130.6","Tissue RNA - bone marrow [nTPM]":"1.7","Tissue RNA - breast [nTPM]":"46.7","Tissue RNA - cerebellum [nTPM]":"118.2","Tissue RNA - cerebral cortex [nTPM]":"105.5","Tissue RNA - cervix [nTPM]":"17.3","Tissue RNA - choroid plexus [nTPM]":"48.9","Tissue RNA - colon [nTPM]":"24.2","Tissue RNA - duodenum [nTPM]":"3.3","Tissue RNA - endometrium 1 [nTPM]":"28.7","Tissue RNA - epididymis [nTPM]":"7.1","Tissue RNA - esophagus [nTPM]":"7.9","Tissue RNA - fallopian tube [nTPM]":"26.4","Tissue RNA - gallbladder [nTPM]":"12.0","Tissue RNA - heart muscle [nTPM]":"132.9","Tissue RNA - hippocampal formation [nTPM]":"105.6","Tissue RNA - hypothalamus [nTPM]":"132.8","Tissue RNA - kidney [nTPM]":"22.9","Tissue RNA - liver [nTPM]":"5.5","Tissue RNA - lung [nTPM]":"18.4","Tissue RNA - lymph node [nTPM]":"5.2","Tissue RNA - medulla oblongata [nTPM]":"126.1","Tissue RNA - midbrain [nTPM]":"135.9","Tissue RNA - ovary [nTPM]":"48.6","Tissue RNA - pancreas [nTPM]":"5.7","Tissue RNA - parathyroid gland [nTPM]":"8.2","Tissue RNA - pituitary gland [nTPM]":"17.7","Tissue RNA - placenta [nTPM]":"10.6","Tissue RNA - pons [nTPM]":"112.9","Tissue RNA - prostate [nTPM]":"15.3","Tissue RNA - rectum [nTPM]":"4.1","Tissue RNA - retina [nTPM]":"15.9","Tissue RNA - salivary gland [nTPM]":"13.4","Tissue RNA - seminal vesicle [nTPM]":"15.0","Tissue RNA - skeletal muscle [nTPM]":"80.4","Tissue RNA - skin 1 [nTPM]":"12.2","Tissue RNA - small intestine [nTPM]":"8.7","Tissue RNA - smooth muscle [nTPM]":"23.2","Tissue RNA - spinal cord [nTPM]":"110.3","Tissue RNA - spleen [nTPM]":"12.2","Tissue RNA - stomach 1 [nTPM]":"12.0","Tissue RNA - testis [nTPM]":"9.6","Tissue RNA - thalamus [nTPM]":"202.3","Tissue RNA - thymus [nTPM]":"4.9","Tissue RNA - thyroid gland [nTPM]":"26.4","Tissue RNA - tongue [nTPM]":"48.0","Tissue RNA - tonsil [nTPM]":"3.3","Tissue RNA - urinary bladder [nTPM]":"29.1","Tissue RNA - vagina [nTPM]":"12.1","Tissue RNA - white matter [nTPM]":"97.8","Cell RNA - A-431 [nTPM]":"0.8","Cell RNA - A549 [nTPM]":"7.9","Cell RNA - AF22 [nTPM]":"15.8","Cell RNA - AN3-CA [nTPM]":"24.5","Cell RNA - ASC diff [nTPM]":"59.6","Cell RNA - ASC TERT1 [nTPM]":"29.2","Cell RNA - BEWO [nTPM]":"40.0","Cell RNA - BJ [nTPM]":"92.9","Cell RNA - BJ hTERT+ [nTPM]":"16.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.2","Cell RNA - CACO-2 [nTPM]":"3.3","Cell RNA - CAPAN-2 [nTPM]":"3.1","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"113.7","Cell RNA - fHDF\/TERT166 [nTPM]":"70.4","Cell RNA - GAMG [nTPM]":"18.6","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"9.0","Cell RNA - HBEC3-KT [nTPM]":"1.8","Cell RNA - HBF TERT88 [nTPM]":"6.1","Cell RNA - HDLM-2 [nTPM]":"7.7","Cell RNA - HEK 293 [nTPM]":"3.1","Cell RNA - HEL [nTPM]":"0.5","Cell RNA - HeLa [nTPM]":"4.8","Cell RNA - Hep G2 [nTPM]":"20.1","Cell RNA - HHSteC [nTPM]":"15.9","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.9","Cell RNA - HSkMC [nTPM]":"41.5","Cell RNA - hTCEpi [nTPM]":"5.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.7","Cell RNA - hTERT-HME1 [nTPM]":"1.4","Cell RNA - hTERT-RPE1 [nTPM]":"13.6","Cell RNA - HUVEC TERT2 [nTPM]":"1.3","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"10.7","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"31.4","Cell RNA - MCF7 [nTPM]":"3.7","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"20.4","Cell RNA - NTERA-2 [nTPM]":"19.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"2.7","Cell RNA - REH [nTPM]":"1.1","Cell RNA - RH-30 [nTPM]":"33.8","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"30.4","Cell RNA - RT4 [nTPM]":"2.0","Cell RNA - SCLC-21H [nTPM]":"18.6","Cell RNA - SH-SY5Y [nTPM]":"42.0","Cell RNA - SiHa [nTPM]":"62.8","Cell RNA - SK-BR-3 [nTPM]":"0.7","Cell RNA - SK-MEL-30 [nTPM]":"45.9","Cell RNA - SuSa [nTPM]":"10.9","Cell RNA - T-47d [nTPM]":"16.1","Cell RNA - THP-1 [nTPM]":"37.7","Cell RNA - TIME [nTPM]":"0.6","Cell RNA - U-138 MG [nTPM]":"23.7","Cell RNA - U-2 OS [nTPM]":"25.3","Cell RNA - U-2197 [nTPM]":"24.3","Cell RNA - U-251 MG [nTPM]":"2.4","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"1.0","Cell RNA - U-698 [nTPM]":"1.2","Cell RNA - U-87 MG [nTPM]":"21.4","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"11.4","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"2.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"4.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"2.7","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"25.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"112.7","Brain RNA - basal ganglia [nTPM]":"130.6","Brain RNA - cerebellum [nTPM]":"118.2","Brain RNA - cerebral cortex [nTPM]":"105.5","Brain RNA - hippocampal formation [nTPM]":"105.6","Brain RNA - hypothalamus [nTPM]":"132.8","Brain RNA - medulla oblongata [nTPM]":"126.1","Brain RNA - midbrain [nTPM]":"135.9","Brain RNA - pons [nTPM]":"112.9","Brain RNA - spinal cord [nTPM]":"110.3","Brain RNA - thalamus [nTPM]":"202.3","Brain RNA - white matter [nTPM]":"97.8","Single Cell Type RNA - Adipocytes [nTPM]":"8.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.5","Single Cell Type RNA - Astrocytes [nTPM]":"54.2","Single Cell Type RNA - B-cells [nTPM]":"0.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"5.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"28.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"34.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"121.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"3.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"58.7","Single Cell Type RNA - Ductal cells [nTPM]":"8.6","Single Cell Type RNA - Early spermatids [nTPM]":"11.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.4","Single Cell Type RNA - Endothelial cells [nTPM]":"14.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.2","Single Cell Type RNA - Fibroblasts [nTPM]":"23.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.5","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"35.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.8","Single Cell Type RNA - Hepatocytes [nTPM]":"1.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"26.3","Single Cell Type RNA - Horizontal cells [nTPM]":"28.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"15.1","Single Cell Type RNA - Langerhans cells [nTPM]":"18.4","Single Cell Type RNA - Late spermatids [nTPM]":"40.0","Single Cell Type RNA - Leydig cells [nTPM]":"23.3","Single Cell Type RNA - Macrophages [nTPM]":"18.2","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"12.2","Single Cell Type RNA - Muller glia cells [nTPM]":"24.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"28.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"34.3","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"27.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.9","Single Cell Type RNA - Spermatocytes [nTPM]":"7.3","Single Cell Type RNA - Spermatogonia [nTPM]":"18.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.4","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"59.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"MSMO1","Gene synonym":["DESP4","ERG25","SC4MOL"],"Ensembl":"ENSG00000052802","Gene description":"Methylsterol monooxygenase 1","Uniprot":["Q15800"],"Chromosome":"4","Position":"165327667-165343164","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"575.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"532.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"GAMG":"416.2","Karpas-707":"412.3","RPTEC TERT1":"399.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055073","HPA056127"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA055073":null,"HPA056127":"AB_2683045"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.97e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.21e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Tissue RNA - adipose tissue [nTPM]":"18.3","Tissue RNA - adrenal gland [nTPM]":"95.2","Tissue RNA - amygdala [nTPM]":"36.7","Tissue RNA - appendix [nTPM]":"20.9","Tissue RNA - basal ganglia [nTPM]":"48.2","Tissue RNA - bone marrow [nTPM]":"10.4","Tissue RNA - breast [nTPM]":"66.2","Tissue RNA - cerebellum [nTPM]":"45.1","Tissue RNA - cerebral cortex [nTPM]":"47.5","Tissue RNA - cervix [nTPM]":"57.1","Tissue RNA - choroid plexus [nTPM]":"37.4","Tissue RNA - colon [nTPM]":"39.2","Tissue RNA - duodenum [nTPM]":"75.7","Tissue RNA - endometrium 1 [nTPM]":"19.1","Tissue RNA - epididymis [nTPM]":"97.0","Tissue RNA - esophagus [nTPM]":"145.7","Tissue RNA - fallopian tube [nTPM]":"20.9","Tissue RNA - gallbladder [nTPM]":"21.7","Tissue RNA - heart muscle [nTPM]":"18.5","Tissue RNA - hippocampal formation [nTPM]":"43.9","Tissue RNA - hypothalamus [nTPM]":"59.2","Tissue RNA - kidney [nTPM]":"52.6","Tissue RNA - liver [nTPM]":"575.6","Tissue RNA - lung [nTPM]":"70.3","Tissue RNA - lymph node [nTPM]":"20.7","Tissue RNA - medulla oblongata [nTPM]":"90.5","Tissue RNA - midbrain [nTPM]":"58.4","Tissue RNA - ovary [nTPM]":"25.7","Tissue RNA - pancreas [nTPM]":"22.6","Tissue RNA - parathyroid gland [nTPM]":"42.9","Tissue RNA - pituitary gland [nTPM]":"18.4","Tissue RNA - placenta [nTPM]":"22.9","Tissue RNA - pons [nTPM]":"78.6","Tissue RNA - prostate [nTPM]":"58.9","Tissue RNA - rectum [nTPM]":"32.9","Tissue RNA - retina [nTPM]":"26.1","Tissue RNA - salivary gland [nTPM]":"34.7","Tissue RNA - seminal vesicle [nTPM]":"12.1","Tissue RNA - skeletal muscle [nTPM]":"5.5","Tissue RNA - skin 1 [nTPM]":"82.5","Tissue RNA - small intestine [nTPM]":"38.1","Tissue RNA - smooth muscle [nTPM]":"16.5","Tissue RNA - spinal cord [nTPM]":"45.0","Tissue RNA - spleen [nTPM]":"11.0","Tissue RNA - stomach 1 [nTPM]":"31.5","Tissue RNA - testis [nTPM]":"52.8","Tissue RNA - thalamus [nTPM]":"48.4","Tissue RNA - thymus [nTPM]":"13.4","Tissue RNA - thyroid gland [nTPM]":"22.4","Tissue RNA - tongue [nTPM]":"6.5","Tissue RNA - tonsil [nTPM]":"27.0","Tissue RNA - urinary bladder [nTPM]":"20.2","Tissue RNA - vagina [nTPM]":"67.0","Tissue RNA - white matter [nTPM]":"61.1","Cell RNA - A-431 [nTPM]":"89.1","Cell RNA - A549 [nTPM]":"21.7","Cell RNA - AF22 [nTPM]":"198.8","Cell RNA - AN3-CA [nTPM]":"36.4","Cell RNA - ASC diff [nTPM]":"97.7","Cell RNA - ASC TERT1 [nTPM]":"312.0","Cell RNA - BEWO [nTPM]":"37.5","Cell RNA - BJ [nTPM]":"35.3","Cell RNA - BJ hTERT+ [nTPM]":"159.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"44.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"123.4","Cell RNA - CACO-2 [nTPM]":"41.5","Cell RNA - CAPAN-2 [nTPM]":"372.9","Cell RNA - Daudi [nTPM]":"43.4","Cell RNA - EFO-21 [nTPM]":"20.6","Cell RNA - fHDF\/TERT166 [nTPM]":"43.1","Cell RNA - GAMG [nTPM]":"416.2","Cell RNA - HaCaT [nTPM]":"71.7","Cell RNA - HAP1 [nTPM]":"101.6","Cell RNA - HBEC3-KT [nTPM]":"366.3","Cell RNA - HBF TERT88 [nTPM]":"49.4","Cell RNA - HDLM-2 [nTPM]":"37.7","Cell RNA - HEK 293 [nTPM]":"63.0","Cell RNA - HEL [nTPM]":"20.0","Cell RNA - HeLa [nTPM]":"20.0","Cell RNA - Hep G2 [nTPM]":"127.6","Cell RNA - HHSteC [nTPM]":"194.9","Cell RNA - HL-60 [nTPM]":"35.8","Cell RNA - HMC-1 [nTPM]":"26.8","Cell RNA - HSkMC [nTPM]":"192.6","Cell RNA - hTCEpi [nTPM]":"237.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"163.6","Cell RNA - hTERT-HME1 [nTPM]":"100.6","Cell RNA - hTERT-RPE1 [nTPM]":"61.1","Cell RNA - HUVEC TERT2 [nTPM]":"58.8","Cell RNA - JURKAT [nTPM]":"55.7","Cell RNA - K-562 [nTPM]":"35.3","Cell RNA - Karpas-707 [nTPM]":"412.3","Cell RNA - LHCN-M2 [nTPM]":"74.6","Cell RNA - MCF7 [nTPM]":"45.7","Cell RNA - MOLT-4 [nTPM]":"32.6","Cell RNA - NB-4 [nTPM]":"58.2","Cell RNA - NTERA-2 [nTPM]":"115.6","Cell RNA - OE19 [nTPM]":"46.9","Cell RNA - PC-3 [nTPM]":"21.0","Cell RNA - REH [nTPM]":"16.8","Cell RNA - RH-30 [nTPM]":"21.8","Cell RNA - RPMI-8226 [nTPM]":"132.3","Cell RNA - RPTEC TERT1 [nTPM]":"399.5","Cell RNA - RT4 [nTPM]":"102.5","Cell RNA - SCLC-21H [nTPM]":"39.7","Cell RNA - SH-SY5Y [nTPM]":"30.0","Cell RNA - SiHa [nTPM]":"54.5","Cell RNA - SK-BR-3 [nTPM]":"77.9","Cell RNA - SK-MEL-30 [nTPM]":"33.9","Cell RNA - SuSa [nTPM]":"121.7","Cell RNA - T-47d [nTPM]":"36.1","Cell RNA - THP-1 [nTPM]":"44.7","Cell RNA - TIME [nTPM]":"67.6","Cell RNA - U-138 MG [nTPM]":"20.6","Cell RNA - U-2 OS [nTPM]":"36.1","Cell RNA - U-2197 [nTPM]":"18.5","Cell RNA - U-251 MG [nTPM]":"24.7","Cell RNA - U-266\/70 [nTPM]":"75.9","Cell RNA - U-266\/84 [nTPM]":"86.5","Cell RNA - U-698 [nTPM]":"58.6","Cell RNA - U-87 MG [nTPM]":"43.9","Cell RNA - U-937 [nTPM]":"36.0","Cell RNA - WM-115 [nTPM]":"28.5","Blood RNA - basophil [nTPM]":"13.7","Blood RNA - classical monocyte [nTPM]":"8.6","Blood RNA - eosinophil [nTPM]":"8.8","Blood RNA - gdT-cell [nTPM]":"34.0","Blood RNA - intermediate monocyte [nTPM]":"11.6","Blood RNA - MAIT T-cell [nTPM]":"25.4","Blood RNA - memory B-cell [nTPM]":"40.6","Blood RNA - memory CD4 T-cell [nTPM]":"31.8","Blood RNA - memory CD8 T-cell [nTPM]":"31.4","Blood RNA - myeloid DC [nTPM]":"15.0","Blood RNA - naive B-cell [nTPM]":"37.6","Blood RNA - naive CD4 T-cell [nTPM]":"34.3","Blood RNA - naive CD8 T-cell [nTPM]":"35.6","Blood RNA - neutrophil [nTPM]":"6.1","Blood RNA - NK-cell [nTPM]":"24.9","Blood RNA - non-classical monocyte [nTPM]":"20.5","Blood RNA - plasmacytoid DC [nTPM]":"19.3","Blood RNA - T-reg [nTPM]":"31.0","Blood RNA - total PBMC [nTPM]":"29.2","Brain RNA - amygdala [nTPM]":"36.7","Brain RNA - basal ganglia [nTPM]":"48.2","Brain RNA - cerebellum [nTPM]":"45.1","Brain RNA - cerebral cortex [nTPM]":"47.5","Brain RNA - hippocampal formation [nTPM]":"43.9","Brain RNA - hypothalamus [nTPM]":"59.2","Brain RNA - medulla oblongata [nTPM]":"90.5","Brain RNA - midbrain [nTPM]":"58.4","Brain RNA - pons [nTPM]":"78.6","Brain RNA - spinal cord [nTPM]":"45.0","Brain RNA - thalamus [nTPM]":"48.4","Brain RNA - white matter [nTPM]":"61.1","Single Cell Type RNA - Adipocytes [nTPM]":"16.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"168.0","Single Cell Type RNA - Astrocytes [nTPM]":"70.5","Single Cell Type RNA - B-cells [nTPM]":"28.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"36.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"70.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"189.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.6","Single Cell Type RNA - Bipolar cells [nTPM]":"33.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"81.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"40.0","Single Cell Type RNA - Club cells [nTPM]":"160.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"69.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"55.6","Single Cell Type RNA - dendritic cells [nTPM]":"20.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"130.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"67.9","Single Cell Type RNA - Early spermatids [nTPM]":"6.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.2","Single Cell Type RNA - Endothelial cells [nTPM]":"30.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"60.7","Single Cell Type RNA - Erythroid cells [nTPM]":"53.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"33.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"71.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"87.0","Single Cell Type RNA - Fibroblasts [nTPM]":"24.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"35.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"44.4","Single Cell Type RNA - granulocytes [nTPM]":"47.7","Single Cell Type RNA - Granulosa cells [nTPM]":"83.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"27.8","Single Cell Type RNA - Hepatocytes [nTPM]":"532.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.3","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"72.8","Single Cell Type RNA - Ionocytes [nTPM]":"170.9","Single Cell Type RNA - Kupffer cells [nTPM]":"28.0","Single Cell Type RNA - Langerhans cells [nTPM]":"11.5","Single Cell Type RNA - Late spermatids [nTPM]":"7.0","Single Cell Type RNA - Leydig cells [nTPM]":"24.8","Single Cell Type RNA - Macrophages [nTPM]":"18.3","Single Cell Type RNA - Melanocytes [nTPM]":"32.0","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"23.6","Single Cell Type RNA - Muller glia cells [nTPM]":"27.2","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"42.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"49.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"86.8","Single Cell Type RNA - Paneth cells [nTPM]":"85.7","Single Cell Type RNA - Peritubular cells [nTPM]":"18.8","Single Cell Type RNA - Plasma cells [nTPM]":"10.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"138.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"46.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"38.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"103.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"50.4","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"35.1","Single Cell Type RNA - Spermatocytes [nTPM]":"8.7","Single Cell Type RNA - Spermatogonia [nTPM]":"15.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"84.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"115.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"123.0","Single Cell Type RNA - T-cells [nTPM]":"22.3","Single Cell Type RNA - Theca cells [nTPM]":"136.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"36.9","Single Cell Type RNA - Urothelial cells [nTPM]":"129.0"},{"Gene":"MSRB3","Gene synonym":["DFNB74","DKFZp686C1178","FLJ36866"],"Ensembl":"ENSG00000174099","Gene description":"Methionine sulfoxide reductase B3","Uniprot":["Q8IXL7"],"Chromosome":"12","Position":"65278643-65491430","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Cardiomyocytes":"2801.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"41.6"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"granulocytes":"41.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"fHDF\/TERT166":"126.1","hTERT-RPE1":"110.6","U-937":"106.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014432"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 43: Cardiomyocytes - Nuclear processes","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014432":"AB_1854146"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.84e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.85e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.17e-4"},"Tissue RNA - adipose tissue [nTPM]":"44.9","Tissue RNA - adrenal gland [nTPM]":"10.7","Tissue RNA - amygdala [nTPM]":"12.9","Tissue RNA - appendix [nTPM]":"20.9","Tissue RNA - basal ganglia [nTPM]":"13.6","Tissue RNA - bone marrow [nTPM]":"21.2","Tissue RNA - breast [nTPM]":"26.3","Tissue RNA - cerebellum [nTPM]":"12.5","Tissue RNA - cerebral cortex [nTPM]":"12.8","Tissue RNA - cervix [nTPM]":"29.5","Tissue RNA - choroid plexus [nTPM]":"18.8","Tissue RNA - colon [nTPM]":"108.0","Tissue RNA - duodenum [nTPM]":"11.9","Tissue RNA - endometrium 1 [nTPM]":"85.8","Tissue RNA - epididymis [nTPM]":"20.1","Tissue RNA - esophagus [nTPM]":"63.0","Tissue RNA - fallopian tube [nTPM]":"41.4","Tissue RNA - gallbladder [nTPM]":"33.2","Tissue RNA - heart muscle [nTPM]":"90.8","Tissue RNA - hippocampal formation [nTPM]":"11.9","Tissue RNA - hypothalamus [nTPM]":"18.3","Tissue RNA - kidney [nTPM]":"10.1","Tissue RNA - liver [nTPM]":"3.8","Tissue RNA - lung [nTPM]":"30.6","Tissue RNA - lymph node [nTPM]":"5.7","Tissue RNA - medulla oblongata [nTPM]":"15.9","Tissue RNA - midbrain [nTPM]":"15.2","Tissue RNA - ovary [nTPM]":"16.9","Tissue RNA - pancreas [nTPM]":"5.8","Tissue RNA - parathyroid gland [nTPM]":"3.2","Tissue RNA - pituitary gland [nTPM]":"6.8","Tissue RNA - placenta [nTPM]":"25.2","Tissue RNA - pons [nTPM]":"13.8","Tissue RNA - prostate [nTPM]":"52.7","Tissue RNA - rectum [nTPM]":"27.8","Tissue RNA - retina [nTPM]":"12.5","Tissue RNA - salivary gland [nTPM]":"10.8","Tissue RNA - seminal vesicle [nTPM]":"103.0","Tissue RNA - skeletal muscle [nTPM]":"104.0","Tissue RNA - skin 1 [nTPM]":"9.7","Tissue RNA - small intestine [nTPM]":"25.6","Tissue RNA - smooth muscle [nTPM]":"123.9","Tissue RNA - spinal cord [nTPM]":"14.6","Tissue RNA - spleen [nTPM]":"13.6","Tissue RNA - stomach 1 [nTPM]":"36.2","Tissue RNA - testis [nTPM]":"5.8","Tissue RNA - thalamus [nTPM]":"18.2","Tissue RNA - thymus [nTPM]":"4.1","Tissue RNA - thyroid gland [nTPM]":"14.5","Tissue RNA - tongue [nTPM]":"69.2","Tissue RNA - tonsil [nTPM]":"3.9","Tissue RNA - urinary bladder [nTPM]":"60.9","Tissue RNA - vagina [nTPM]":"23.7","Tissue RNA - white matter [nTPM]":"11.8","Cell RNA - A-431 [nTPM]":"8.8","Cell RNA - A549 [nTPM]":"19.2","Cell RNA - AF22 [nTPM]":"16.4","Cell RNA - AN3-CA [nTPM]":"75.9","Cell RNA - ASC diff [nTPM]":"71.6","Cell RNA - ASC TERT1 [nTPM]":"63.0","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"87.0","Cell RNA - BJ hTERT+ [nTPM]":"92.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"33.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.8","Cell RNA - CACO-2 [nTPM]":"0.7","Cell RNA - CAPAN-2 [nTPM]":"1.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"18.3","Cell RNA - fHDF\/TERT166 [nTPM]":"126.1","Cell RNA - GAMG [nTPM]":"10.5","Cell RNA - HaCaT [nTPM]":"1.9","Cell RNA - HAP1 [nTPM]":"7.7","Cell RNA - HBEC3-KT [nTPM]":"22.1","Cell RNA - HBF TERT88 [nTPM]":"30.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"15.9","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"16.7","Cell RNA - Hep G2 [nTPM]":"0.9","Cell RNA - HHSteC [nTPM]":"46.6","Cell RNA - HL-60 [nTPM]":"47.1","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"33.4","Cell RNA - hTCEpi [nTPM]":"11.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"28.1","Cell RNA - hTERT-HME1 [nTPM]":"39.0","Cell RNA - hTERT-RPE1 [nTPM]":"110.6","Cell RNA - HUVEC TERT2 [nTPM]":"68.2","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"76.8","Cell RNA - MCF7 [nTPM]":"2.9","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"11.0","Cell RNA - NTERA-2 [nTPM]":"5.4","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"10.4","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"22.0","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"7.5","Cell RNA - RT4 [nTPM]":"1.0","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"7.9","Cell RNA - SiHa [nTPM]":"30.0","Cell RNA - SK-BR-3 [nTPM]":"1.8","Cell RNA - SK-MEL-30 [nTPM]":"21.9","Cell RNA - SuSa [nTPM]":"16.8","Cell RNA - T-47d [nTPM]":"14.1","Cell RNA - THP-1 [nTPM]":"44.5","Cell RNA - TIME [nTPM]":"78.9","Cell RNA - U-138 MG [nTPM]":"42.3","Cell RNA - U-2 OS [nTPM]":"22.8","Cell RNA - U-2197 [nTPM]":"19.5","Cell RNA - U-251 MG [nTPM]":"34.2","Cell RNA - U-266\/70 [nTPM]":"8.0","Cell RNA - U-266\/84 [nTPM]":"6.7","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"11.5","Cell RNA - U-937 [nTPM]":"106.7","Cell RNA - WM-115 [nTPM]":"26.9","Blood RNA - basophil [nTPM]":"15.0","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"41.6","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"6.8","Blood RNA - NK-cell [nTPM]":"8.3","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"10.8","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"12.9","Brain RNA - basal ganglia [nTPM]":"13.6","Brain RNA - cerebellum [nTPM]":"12.5","Brain RNA - cerebral cortex [nTPM]":"12.8","Brain RNA - hippocampal formation [nTPM]":"11.9","Brain RNA - hypothalamus [nTPM]":"18.3","Brain RNA - medulla oblongata [nTPM]":"15.9","Brain RNA - midbrain [nTPM]":"15.2","Brain RNA - pons [nTPM]":"13.8","Brain RNA - spinal cord [nTPM]":"14.6","Brain RNA - thalamus [nTPM]":"18.2","Brain RNA - white matter [nTPM]":"11.8","Single Cell Type RNA - Adipocytes [nTPM]":"55.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.4","Single Cell Type RNA - Astrocytes [nTPM]":"76.7","Single Cell Type RNA - B-cells [nTPM]":"0.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"22.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"45.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2801.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"1.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"8.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"9.3","Single Cell Type RNA - Early spermatids [nTPM]":"5.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.7","Single Cell Type RNA - Endothelial cells [nTPM]":"154.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"17.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"37.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"108.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"7.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.5","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"56.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"13.7","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"12.5","Single Cell Type RNA - Macrophages [nTPM]":"4.0","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"62.8","Single Cell Type RNA - monocytes [nTPM]":"1.6","Single Cell Type RNA - Muller glia cells [nTPM]":"44.4","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"37.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"116.6","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.6","Single Cell Type RNA - Sertoli cells [nTPM]":"105.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"37.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"218.7","Single Cell Type RNA - Spermatocytes [nTPM]":"4.2","Single Cell Type RNA - Spermatogonia [nTPM]":"4.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"2.4","Single Cell Type RNA - Theca cells [nTPM]":"10.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"2.9"},{"Gene":"MST1R","Gene synonym":["CD136","CDw136","PTK8","RON","SEA"],"Ensembl":"ENSG00000164078","Gene description":"Macrophage stimulating 1 receptor","Uniprot":["Q04912"],"Chromosome":"3","Position":"49887002-49903873","Protein class":["CD markers","Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity","Innate immunity"],"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"62.3","stomach 1":"42.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"25.6","Distal enterocytes":"53.9","Gastric mucus-secreting cells":"108.6","Intestinal goblet cells":"25.7","Pancreatic endocrine cells":"31.2","Paneth cells":"30.3","Proximal enterocytes":"27.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"39.3","CAPAN-2":"98.8","HaCaT":"56.3","HBEC3-KT":"59.4","hTCEpi":"83.4","RT4":"67.9"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007657","HPA008180","CAB008972"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB008972":null,"HPA007657":"AB_1079292","HPA008180":"AB_1079291"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.00e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.33e-5"},"Tissue RNA - adipose tissue [nTPM]":"5.1","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"1.1","Tissue RNA - appendix [nTPM]":"5.1","Tissue RNA - basal ganglia [nTPM]":"1.1","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"3.8","Tissue RNA - cerebellum [nTPM]":"1.1","Tissue RNA - cerebral cortex [nTPM]":"1.7","Tissue RNA - cervix [nTPM]":"5.7","Tissue RNA - choroid plexus [nTPM]":"1.3","Tissue RNA - colon [nTPM]":"26.5","Tissue RNA - duodenum [nTPM]":"25.2","Tissue RNA - endometrium 1 [nTPM]":"1.3","Tissue RNA - epididymis [nTPM]":"1.2","Tissue RNA - esophagus [nTPM]":"17.5","Tissue RNA - fallopian tube [nTPM]":"1.7","Tissue RNA - gallbladder [nTPM]":"11.4","Tissue RNA - heart muscle [nTPM]":"3.2","Tissue RNA - hippocampal formation [nTPM]":"1.1","Tissue RNA - hypothalamus [nTPM]":"0.9","Tissue RNA - kidney [nTPM]":"3.4","Tissue RNA - liver [nTPM]":"1.1","Tissue RNA - lung [nTPM]":"9.5","Tissue RNA - lymph node [nTPM]":"2.5","Tissue RNA - medulla oblongata [nTPM]":"0.9","Tissue RNA - midbrain [nTPM]":"0.8","Tissue RNA - ovary [nTPM]":"1.0","Tissue RNA - pancreas [nTPM]":"5.8","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"2.7","Tissue RNA - placenta [nTPM]":"0.8","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"4.7","Tissue RNA - rectum [nTPM]":"20.1","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"5.4","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"1.3","Tissue RNA - skin 1 [nTPM]":"62.3","Tissue RNA - small intestine [nTPM]":"23.9","Tissue RNA - smooth muscle [nTPM]":"2.0","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"1.6","Tissue RNA - stomach 1 [nTPM]":"42.6","Tissue RNA - testis [nTPM]":"8.4","Tissue RNA - thalamus [nTPM]":"0.9","Tissue RNA - thymus [nTPM]":"8.8","Tissue RNA - thyroid gland [nTPM]":"3.4","Tissue RNA - tongue [nTPM]":"0.7","Tissue RNA - tonsil [nTPM]":"5.6","Tissue RNA - urinary bladder [nTPM]":"9.2","Tissue RNA - vagina [nTPM]":"11.5","Tissue RNA - white matter [nTPM]":"1.0","Cell RNA - A-431 [nTPM]":"39.3","Cell RNA - A549 [nTPM]":"14.4","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.6","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"2.2","Cell RNA - BJ [nTPM]":"0.5","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"4.1","Cell RNA - CAPAN-2 [nTPM]":"98.8","Cell RNA - Daudi [nTPM]":"1.7","Cell RNA - EFO-21 [nTPM]":"8.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.5","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"56.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"59.4","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.9","Cell RNA - HEK 293 [nTPM]":"1.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"25.9","Cell RNA - Hep G2 [nTPM]":"0.9","Cell RNA - HHSteC [nTPM]":"0.9","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.2","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"83.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"11.7","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.8","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"5.1","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"33.1","Cell RNA - PC-3 [nTPM]":"34.6","Cell RNA - REH [nTPM]":"2.9","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.1","Cell RNA - RPTEC TERT1 [nTPM]":"35.8","Cell RNA - RT4 [nTPM]":"67.9","Cell RNA - SCLC-21H [nTPM]":"1.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"11.5","Cell RNA - SK-BR-3 [nTPM]":"22.6","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"17.7","Cell RNA - THP-1 [nTPM]":"0.9","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.1","Brain RNA - basal ganglia [nTPM]":"1.1","Brain RNA - cerebellum [nTPM]":"1.1","Brain RNA - cerebral cortex [nTPM]":"1.7","Brain RNA - hippocampal formation [nTPM]":"1.1","Brain RNA - hypothalamus [nTPM]":"0.9","Brain RNA - medulla oblongata [nTPM]":"0.9","Brain RNA - midbrain [nTPM]":"0.8","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"0.9","Brain RNA - white matter [nTPM]":"1.0","Single Cell Type RNA - Adipocytes [nTPM]":"1.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"10.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"53.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.4","Single Cell Type RNA - Early spermatids [nTPM]":"15.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.8","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"0.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"108.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"25.7","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.4","Single Cell Type RNA - Late spermatids [nTPM]":"10.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"31.2","Single Cell Type RNA - Paneth cells [nTPM]":"30.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"27.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.9","Single Cell Type RNA - Spermatocytes [nTPM]":"1.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.1","Single Cell Type RNA - Urothelial cells [nTPM]":"6.2"},{"Gene":"MT-CO1","Gene synonym":["COI","COX1","MTCO1"],"Ensembl":"ENSG00000198804","Gene description":"Mitochondrially encoded cytochrome c oxidase I","Uniprot":["P00395"],"Chromosome":"MT","Position":"5904-7445","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Deafness","Disease variant","Leber hereditary optic neuropathy","Non-syndromic deafness","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"222644.8","heart muscle":"255389.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"107039.5","Hepatocytes":"59794.3","Proximal enterocytes":"98329.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"54167.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016241","HPA069328"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB016241":"AB_2229888","HPA069328":"AB_2686122"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.29e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Tissue RNA - adipose tissue [nTPM]":"22006.8","Tissue RNA - adrenal gland [nTPM]":"46968.9","Tissue RNA - amygdala [nTPM]":"171347.0","Tissue RNA - appendix [nTPM]":"8727.7","Tissue RNA - basal ganglia [nTPM]":"151652.8","Tissue RNA - bone marrow [nTPM]":"11321.8","Tissue RNA - breast [nTPM]":"17952.5","Tissue RNA - cerebellum [nTPM]":"132201.9","Tissue RNA - cerebral cortex [nTPM]":"222644.8","Tissue RNA - cervix [nTPM]":"10440.9","Tissue RNA - choroid plexus [nTPM]":"179120.2","Tissue RNA - colon [nTPM]":"42606.0","Tissue RNA - duodenum [nTPM]":"27505.7","Tissue RNA - endometrium 1 [nTPM]":"11582.9","Tissue RNA - epididymis [nTPM]":"14226.0","Tissue RNA - esophagus [nTPM]":"20791.8","Tissue RNA - fallopian tube [nTPM]":"10700.5","Tissue RNA - gallbladder [nTPM]":"11452.7","Tissue RNA - heart muscle [nTPM]":"255389.3","Tissue RNA - hippocampal formation [nTPM]":"151507.6","Tissue RNA - hypothalamus [nTPM]":"137459.2","Tissue RNA - kidney [nTPM]":"63061.8","Tissue RNA - liver [nTPM]":"96575.5","Tissue RNA - lung [nTPM]":"12744.7","Tissue RNA - lymph node [nTPM]":"9111.4","Tissue RNA - medulla oblongata [nTPM]":"176794.8","Tissue RNA - midbrain [nTPM]":"152802.2","Tissue RNA - ovary [nTPM]":"8124.5","Tissue RNA - pancreas [nTPM]":"19467.4","Tissue RNA - parathyroid gland [nTPM]":"41236.2","Tissue RNA - pituitary gland [nTPM]":"7420.2","Tissue RNA - placenta [nTPM]":"10527.8","Tissue RNA - pons [nTPM]":"168465.9","Tissue RNA - prostate [nTPM]":"12427.0","Tissue RNA - rectum [nTPM]":"28389.7","Tissue RNA - retina [nTPM]":"12503.0","Tissue RNA - salivary gland [nTPM]":"23260.1","Tissue RNA - seminal vesicle [nTPM]":"17753.2","Tissue RNA - skeletal muscle [nTPM]":"147209.5","Tissue RNA - skin 1 [nTPM]":"26849.0","Tissue RNA - small intestine [nTPM]":"35366.3","Tissue RNA - smooth muscle [nTPM]":"13146.2","Tissue RNA - spinal cord [nTPM]":"138626.1","Tissue RNA - spleen [nTPM]":"16284.7","Tissue RNA - stomach 1 [nTPM]":"44852.9","Tissue RNA - testis [nTPM]":"10932.5","Tissue RNA - thalamus [nTPM]":"176888.2","Tissue RNA - thymus [nTPM]":"7461.1","Tissue RNA - thyroid gland [nTPM]":"14056.3","Tissue RNA - tongue [nTPM]":"184587.7","Tissue RNA - tonsil [nTPM]":"8381.2","Tissue RNA - urinary bladder [nTPM]":"17415.3","Tissue RNA - vagina [nTPM]":"10559.7","Tissue RNA - white matter [nTPM]":"131378.4","Cell RNA - A-431 [nTPM]":"5837.6","Cell RNA - A549 [nTPM]":"8554.3","Cell RNA - AF22 [nTPM]":"11384.1","Cell RNA - AN3-CA [nTPM]":"12431.0","Cell RNA - ASC diff [nTPM]":"25510.2","Cell RNA - ASC TERT1 [nTPM]":"11563.1","Cell RNA - BEWO [nTPM]":"12037.2","Cell RNA - BJ [nTPM]":"12867.2","Cell RNA - BJ hTERT+ [nTPM]":"4284.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3189.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5257.4","Cell RNA - CACO-2 [nTPM]":"10383.6","Cell RNA - CAPAN-2 [nTPM]":"18320.5","Cell RNA - Daudi [nTPM]":"15138.9","Cell RNA - EFO-21 [nTPM]":"6040.7","Cell RNA - fHDF\/TERT166 [nTPM]":"9857.6","Cell RNA - GAMG [nTPM]":"3118.2","Cell RNA - HaCaT [nTPM]":"21430.9","Cell RNA - HAP1 [nTPM]":"1326.6","Cell RNA - HBEC3-KT [nTPM]":"11407.4","Cell RNA - HBF TERT88 [nTPM]":"4515.1","Cell RNA - HDLM-2 [nTPM]":"7226.0","Cell RNA - HEK 293 [nTPM]":"8040.6","Cell RNA - HEL [nTPM]":"9130.6","Cell RNA - HeLa [nTPM]":"54167.9","Cell RNA - Hep G2 [nTPM]":"19725.4","Cell RNA - HHSteC [nTPM]":"3521.2","Cell RNA - HL-60 [nTPM]":"5336.1","Cell RNA - HMC-1 [nTPM]":"11055.5","Cell RNA - HSkMC [nTPM]":"13603.9","Cell RNA - hTCEpi [nTPM]":"11589.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3149.9","Cell RNA - hTERT-HME1 [nTPM]":"6917.5","Cell RNA - hTERT-RPE1 [nTPM]":"14668.4","Cell RNA - HUVEC TERT2 [nTPM]":"3902.1","Cell RNA - JURKAT [nTPM]":"8485.5","Cell RNA - K-562 [nTPM]":"5916.3","Cell RNA - Karpas-707 [nTPM]":"10551.1","Cell RNA - LHCN-M2 [nTPM]":"9525.6","Cell RNA - MCF7 [nTPM]":"14037.0","Cell RNA - MOLT-4 [nTPM]":"4378.4","Cell RNA - NB-4 [nTPM]":"23591.9","Cell RNA - NTERA-2 [nTPM]":"2905.0","Cell RNA - OE19 [nTPM]":"7814.2","Cell RNA - PC-3 [nTPM]":"6900.5","Cell RNA - REH [nTPM]":"5664.0","Cell RNA - RH-30 [nTPM]":"3401.6","Cell RNA - RPMI-8226 [nTPM]":"9177.9","Cell RNA - RPTEC TERT1 [nTPM]":"15910.6","Cell RNA - RT4 [nTPM]":"15016.1","Cell RNA - SCLC-21H [nTPM]":"5414.7","Cell RNA - SH-SY5Y [nTPM]":"7189.1","Cell RNA - SiHa [nTPM]":"4466.7","Cell RNA - SK-BR-3 [nTPM]":"17018.9","Cell RNA - SK-MEL-30 [nTPM]":"8305.7","Cell RNA - SuSa [nTPM]":"13626.1","Cell RNA - T-47d [nTPM]":"9809.7","Cell RNA - THP-1 [nTPM]":"17703.3","Cell RNA - TIME [nTPM]":"15637.8","Cell RNA - U-138 MG [nTPM]":"12617.8","Cell RNA - U-2 OS [nTPM]":"8438.9","Cell RNA - U-2197 [nTPM]":"12565.9","Cell RNA - U-251 MG [nTPM]":"6642.1","Cell RNA - U-266\/70 [nTPM]":"4951.2","Cell RNA - U-266\/84 [nTPM]":"5072.9","Cell RNA - U-698 [nTPM]":"3542.6","Cell RNA - U-87 MG [nTPM]":"6235.7","Cell RNA - U-937 [nTPM]":"13711.8","Cell RNA - WM-115 [nTPM]":"6294.4","Blood RNA - basophil [nTPM]":"5305.8","Blood RNA - classical monocyte [nTPM]":"9759.2","Blood RNA - eosinophil [nTPM]":"3824.6","Blood RNA - gdT-cell [nTPM]":"3085.1","Blood RNA - intermediate monocyte [nTPM]":"4907.9","Blood RNA - MAIT T-cell [nTPM]":"3420.5","Blood RNA - memory B-cell [nTPM]":"5374.6","Blood RNA - memory CD4 T-cell [nTPM]":"3047.3","Blood RNA - memory CD8 T-cell [nTPM]":"3425.6","Blood RNA - myeloid DC [nTPM]":"3444.6","Blood RNA - naive B-cell [nTPM]":"5567.3","Blood RNA - naive CD4 T-cell [nTPM]":"3080.8","Blood RNA - naive CD8 T-cell [nTPM]":"3911.2","Blood RNA - neutrophil [nTPM]":"1900.4","Blood RNA - NK-cell [nTPM]":"3759.1","Blood RNA - non-classical monocyte [nTPM]":"5775.1","Blood RNA - plasmacytoid DC [nTPM]":"4847.5","Blood RNA - T-reg [nTPM]":"2947.7","Blood RNA - total PBMC [nTPM]":"3929.0","Brain RNA - amygdala [nTPM]":"171347.0","Brain RNA - basal ganglia [nTPM]":"151652.8","Brain RNA - cerebellum [nTPM]":"132201.9","Brain RNA - cerebral cortex [nTPM]":"222644.8","Brain RNA - hippocampal formation [nTPM]":"151507.6","Brain RNA - hypothalamus [nTPM]":"137459.2","Brain RNA - medulla oblongata [nTPM]":"176794.8","Brain RNA - midbrain [nTPM]":"152802.2","Brain RNA - pons [nTPM]":"168465.9","Brain RNA - spinal cord [nTPM]":"138626.1","Brain RNA - thalamus [nTPM]":"176888.2","Brain RNA - white matter [nTPM]":"131378.4","Single Cell Type RNA - Adipocytes [nTPM]":"3924.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"2900.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3897.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"13282.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9769.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9713.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22625.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"20857.7","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"12033.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11841.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"107039.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"30777.5","Single Cell Type RNA - Club cells [nTPM]":"16135.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"19596.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"9288.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"40726.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"4255.4","Single Cell Type RNA - Ductal cells [nTPM]":"7191.4","Single Cell Type RNA - Early spermatids [nTPM]":"1555.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13044.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9033.9","Single Cell Type RNA - Endothelial cells [nTPM]":"7847.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7514.7","Single Cell Type RNA - Erythroid cells [nTPM]":"45610.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5089.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"6305.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19235.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25645.6","Single Cell Type RNA - granulocytes [nTPM]":"3832.6","Single Cell Type RNA - Granulosa cells [nTPM]":"20400.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25951.4","Single Cell Type RNA - Hepatocytes [nTPM]":"59794.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24302.1","Single Cell Type RNA - Ionocytes [nTPM]":"19071.0","Single Cell Type RNA - Kupffer cells [nTPM]":"45533.4","Single Cell Type RNA - Langerhans cells [nTPM]":"7744.0","Single Cell Type RNA - Late spermatids [nTPM]":"7398.4","Single Cell Type RNA - Leydig cells [nTPM]":"11696.4","Single Cell Type RNA - Macrophages [nTPM]":"12124.7","Single Cell Type RNA - Melanocytes [nTPM]":"6894.2","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"15180.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"8901.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6410.5","Single Cell Type RNA - Paneth cells [nTPM]":"23865.9","Single Cell Type RNA - Peritubular cells [nTPM]":"8490.1","Single Cell Type RNA - Plasma cells [nTPM]":"13829.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9441.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"98329.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"33652.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10474.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13614.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11019.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9403.5","Single Cell Type RNA - Spermatocytes [nTPM]":"12096.5","Single Cell Type RNA - Spermatogonia [nTPM]":"14338.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"27110.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11475.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"11502.4","Single Cell Type RNA - Theca cells [nTPM]":"15179.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"27138.6","Single Cell Type RNA - Urothelial cells [nTPM]":"21770.7"},{"Gene":"MT-CO2","Gene synonym":["CO2","COX2","MTCO2"],"Ensembl":"ENSG00000198712","Gene description":"Mitochondrially encoded cytochrome c oxidase II","Uniprot":["P00403"],"Chromosome":"MT","Position":"7586-8269","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"164780.5","heart muscle":"210840.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Cardiomyocytes":"709929.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"73985.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016243","HPA051505","HPA054758"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"240000","Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB016243":"AB_2066366","HPA051505":"AB_2681511","HPA054758":"AB_2682595"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.89e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.10e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-3"},"Tissue RNA - adipose tissue [nTPM]":"27287.7","Tissue RNA - adrenal gland [nTPM]":"50118.4","Tissue RNA - amygdala [nTPM]":"114427.0","Tissue RNA - appendix [nTPM]":"5960.9","Tissue RNA - basal ganglia [nTPM]":"114629.6","Tissue RNA - bone marrow [nTPM]":"9211.1","Tissue RNA - breast [nTPM]":"23112.5","Tissue RNA - cerebellum [nTPM]":"102567.5","Tissue RNA - cerebral cortex [nTPM]":"164780.5","Tissue RNA - cervix [nTPM]":"8637.9","Tissue RNA - choroid plexus [nTPM]":"123709.0","Tissue RNA - colon [nTPM]":"47542.8","Tissue RNA - duodenum [nTPM]":"18239.3","Tissue RNA - endometrium 1 [nTPM]":"10045.0","Tissue RNA - epididymis [nTPM]":"10813.1","Tissue RNA - esophagus [nTPM]":"24529.5","Tissue RNA - fallopian tube [nTPM]":"11015.1","Tissue RNA - gallbladder [nTPM]":"5914.4","Tissue RNA - heart muscle [nTPM]":"210840.8","Tissue RNA - hippocampal formation [nTPM]":"108795.0","Tissue RNA - hypothalamus [nTPM]":"110116.5","Tissue RNA - kidney [nTPM]":"112074.1","Tissue RNA - liver [nTPM]":"105449.6","Tissue RNA - lung [nTPM]":"14032.6","Tissue RNA - lymph node [nTPM]":"6314.3","Tissue RNA - medulla oblongata [nTPM]":"129884.9","Tissue RNA - midbrain [nTPM]":"115346.3","Tissue RNA - ovary [nTPM]":"7950.6","Tissue RNA - pancreas [nTPM]":"24515.9","Tissue RNA - parathyroid gland [nTPM]":"29782.0","Tissue RNA - pituitary gland [nTPM]":"16861.9","Tissue RNA - placenta [nTPM]":"10397.8","Tissue RNA - pons [nTPM]":"125082.8","Tissue RNA - prostate [nTPM]":"25688.4","Tissue RNA - rectum [nTPM]":"24989.1","Tissue RNA - retina [nTPM]":"8983.3","Tissue RNA - salivary gland [nTPM]":"21379.6","Tissue RNA - seminal vesicle [nTPM]":"12907.0","Tissue RNA - skeletal muscle [nTPM]":"93258.6","Tissue RNA - skin 1 [nTPM]":"22997.0","Tissue RNA - small intestine [nTPM]":"36121.9","Tissue RNA - smooth muscle [nTPM]":"9693.6","Tissue RNA - spinal cord [nTPM]":"102620.8","Tissue RNA - spleen [nTPM]":"18194.3","Tissue RNA - stomach 1 [nTPM]":"45409.4","Tissue RNA - testis [nTPM]":"14516.5","Tissue RNA - thalamus [nTPM]":"123032.8","Tissue RNA - thymus [nTPM]":"6034.4","Tissue RNA - thyroid gland [nTPM]":"16877.7","Tissue RNA - tongue [nTPM]":"109930.2","Tissue RNA - tonsil [nTPM]":"7889.2","Tissue RNA - urinary bladder [nTPM]":"21068.8","Tissue RNA - vagina [nTPM]":"13184.5","Tissue RNA - white matter [nTPM]":"102646.5","Cell RNA - A-431 [nTPM]":"6276.2","Cell RNA - A549 [nTPM]":"9796.4","Cell RNA - AF22 [nTPM]":"12777.6","Cell RNA - AN3-CA [nTPM]":"12396.3","Cell RNA - ASC diff [nTPM]":"25548.5","Cell RNA - ASC TERT1 [nTPM]":"9745.3","Cell RNA - BEWO [nTPM]":"9393.2","Cell RNA - BJ [nTPM]":"7927.6","Cell RNA - BJ hTERT+ [nTPM]":"6429.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4420.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6584.3","Cell RNA - CACO-2 [nTPM]":"10616.0","Cell RNA - CAPAN-2 [nTPM]":"13681.5","Cell RNA - Daudi [nTPM]":"12924.1","Cell RNA - EFO-21 [nTPM]":"6467.6","Cell RNA - fHDF\/TERT166 [nTPM]":"11751.8","Cell RNA - GAMG [nTPM]":"4522.1","Cell RNA - HaCaT [nTPM]":"23074.6","Cell RNA - HAP1 [nTPM]":"1724.1","Cell RNA - HBEC3-KT [nTPM]":"16319.1","Cell RNA - HBF TERT88 [nTPM]":"5925.8","Cell RNA - HDLM-2 [nTPM]":"10089.3","Cell RNA - HEK 293 [nTPM]":"8726.0","Cell RNA - HEL [nTPM]":"9297.7","Cell RNA - HeLa [nTPM]":"73985.8","Cell RNA - Hep G2 [nTPM]":"20756.8","Cell RNA - HHSteC [nTPM]":"5543.0","Cell RNA - HL-60 [nTPM]":"7919.2","Cell RNA - HMC-1 [nTPM]":"9987.0","Cell RNA - HSkMC [nTPM]":"14433.8","Cell RNA - hTCEpi [nTPM]":"23568.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2276.3","Cell RNA - hTERT-HME1 [nTPM]":"8072.8","Cell RNA - hTERT-RPE1 [nTPM]":"14337.8","Cell RNA - HUVEC TERT2 [nTPM]":"4979.3","Cell RNA - JURKAT [nTPM]":"12668.7","Cell RNA - K-562 [nTPM]":"8862.9","Cell RNA - Karpas-707 [nTPM]":"12216.0","Cell RNA - LHCN-M2 [nTPM]":"12212.6","Cell RNA - MCF7 [nTPM]":"13490.3","Cell RNA - MOLT-4 [nTPM]":"5804.8","Cell RNA - NB-4 [nTPM]":"22519.7","Cell RNA - NTERA-2 [nTPM]":"3353.4","Cell RNA - OE19 [nTPM]":"12256.7","Cell RNA - PC-3 [nTPM]":"6160.6","Cell RNA - REH [nTPM]":"5998.2","Cell RNA - RH-30 [nTPM]":"3899.6","Cell RNA - RPMI-8226 [nTPM]":"10866.7","Cell RNA - RPTEC TERT1 [nTPM]":"17578.2","Cell RNA - RT4 [nTPM]":"17096.2","Cell RNA - SCLC-21H [nTPM]":"4758.2","Cell RNA - SH-SY5Y [nTPM]":"7830.6","Cell RNA - SiHa [nTPM]":"6527.3","Cell RNA - SK-BR-3 [nTPM]":"15842.4","Cell RNA - SK-MEL-30 [nTPM]":"11881.3","Cell RNA - SuSa [nTPM]":"18742.2","Cell RNA - T-47d [nTPM]":"11084.6","Cell RNA - THP-1 [nTPM]":"31596.4","Cell RNA - TIME [nTPM]":"12345.0","Cell RNA - U-138 MG [nTPM]":"10576.0","Cell RNA - U-2 OS [nTPM]":"9043.3","Cell RNA - U-2197 [nTPM]":"10116.0","Cell RNA - U-251 MG [nTPM]":"5740.6","Cell RNA - U-266\/70 [nTPM]":"6151.2","Cell RNA - U-266\/84 [nTPM]":"6563.0","Cell RNA - U-698 [nTPM]":"7590.8","Cell RNA - U-87 MG [nTPM]":"5638.0","Cell RNA - U-937 [nTPM]":"15586.1","Cell RNA - WM-115 [nTPM]":"7129.7","Blood RNA - basophil [nTPM]":"20953.0","Blood RNA - classical monocyte [nTPM]":"13541.7","Blood RNA - eosinophil [nTPM]":"15753.7","Blood RNA - gdT-cell [nTPM]":"5586.8","Blood RNA - intermediate monocyte [nTPM]":"8887.6","Blood RNA - MAIT T-cell [nTPM]":"6782.0","Blood RNA - memory B-cell [nTPM]":"11844.8","Blood RNA - memory CD4 T-cell [nTPM]":"6189.5","Blood RNA - memory CD8 T-cell [nTPM]":"6338.9","Blood RNA - myeloid DC [nTPM]":"6316.7","Blood RNA - naive B-cell [nTPM]":"10947.0","Blood RNA - naive CD4 T-cell [nTPM]":"6386.1","Blood RNA - naive CD8 T-cell [nTPM]":"7947.1","Blood RNA - neutrophil [nTPM]":"5329.9","Blood RNA - NK-cell [nTPM]":"6846.5","Blood RNA - non-classical monocyte [nTPM]":"10055.3","Blood RNA - plasmacytoid DC [nTPM]":"8426.1","Blood RNA - T-reg [nTPM]":"5367.4","Blood RNA - total PBMC [nTPM]":"7670.7","Brain RNA - amygdala [nTPM]":"114427.0","Brain RNA - basal ganglia [nTPM]":"114629.6","Brain RNA - cerebellum [nTPM]":"102567.5","Brain RNA - cerebral cortex [nTPM]":"164780.5","Brain RNA - hippocampal formation [nTPM]":"108795.0","Brain RNA - hypothalamus [nTPM]":"110116.5","Brain RNA - medulla oblongata [nTPM]":"129884.9","Brain RNA - midbrain [nTPM]":"115346.3","Brain RNA - pons [nTPM]":"125082.8","Brain RNA - spinal cord [nTPM]":"102620.8","Brain RNA - thalamus [nTPM]":"123032.8","Brain RNA - white matter [nTPM]":"102646.5","Single Cell Type RNA - Adipocytes [nTPM]":"4337.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"1445.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1999.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"11825.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6754.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8961.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22171.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22140.9","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"11994.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16742.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"709929.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"18464.2","Single Cell Type RNA - Club cells [nTPM]":"10323.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"18597.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"7569.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"29582.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3709.5","Single Cell Type RNA - Ductal cells [nTPM]":"3684.4","Single Cell Type RNA - Early spermatids [nTPM]":"1119.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12108.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6979.9","Single Cell Type RNA - Endothelial cells [nTPM]":"16215.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6396.9","Single Cell Type RNA - Erythroid cells [nTPM]":"27238.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4873.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"10942.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19089.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20683.3","Single Cell Type RNA - granulocytes [nTPM]":"2144.6","Single Cell Type RNA - Granulosa cells [nTPM]":"17185.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15141.7","Single Cell Type RNA - Hepatocytes [nTPM]":"53416.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17158.1","Single Cell Type RNA - Ionocytes [nTPM]":"14290.0","Single Cell Type RNA - Kupffer cells [nTPM]":"26774.7","Single Cell Type RNA - Langerhans cells [nTPM]":"4814.0","Single Cell Type RNA - Late spermatids [nTPM]":"5284.9","Single Cell Type RNA - Leydig cells [nTPM]":"7663.3","Single Cell Type RNA - Macrophages [nTPM]":"9292.7","Single Cell Type RNA - Melanocytes [nTPM]":"5140.4","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"7967.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"6828.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4709.1","Single Cell Type RNA - Paneth cells [nTPM]":"15133.6","Single Cell Type RNA - Peritubular cells [nTPM]":"5123.0","Single Cell Type RNA - Plasma cells [nTPM]":"14109.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5949.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"40280.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22569.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7617.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"7060.4","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9361.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14171.2","Single Cell Type RNA - Spermatocytes [nTPM]":"7120.5","Single Cell Type RNA - Spermatogonia [nTPM]":"8965.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26952.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6702.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"8863.0","Single Cell Type RNA - Theca cells [nTPM]":"13639.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19371.4","Single Cell Type RNA - Urothelial cells [nTPM]":"14261.8"},{"Gene":"MT-CO3","Gene synonym":["CO3","COIII","COX3","MTCO3"],"Ensembl":"ENSG00000198938","Gene description":"Mitochondrially encoded cytochrome c oxidase III","Uniprot":["P00414"],"Chromosome":"MT","Position":"9207-9990","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Leber hereditary optic neuropathy","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"189825.4","heart muscle":"231090.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"98114.9","Proximal enterocytes":"47697.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"47821.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042788"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042788":"AB_10793985"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.01e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.04e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Tissue RNA - adipose tissue [nTPM]":"27612.7","Tissue RNA - adrenal gland [nTPM]":"53681.0","Tissue RNA - amygdala [nTPM]":"106768.6","Tissue RNA - appendix [nTPM]":"6403.7","Tissue RNA - basal ganglia [nTPM]":"100201.0","Tissue RNA - bone marrow [nTPM]":"11914.6","Tissue RNA - breast [nTPM]":"26962.2","Tissue RNA - cerebellum [nTPM]":"92217.9","Tissue RNA - cerebral cortex [nTPM]":"189825.4","Tissue RNA - cervix [nTPM]":"9972.2","Tissue RNA - choroid plexus [nTPM]":"122787.3","Tissue RNA - colon [nTPM]":"41553.8","Tissue RNA - duodenum [nTPM]":"21299.6","Tissue RNA - endometrium 1 [nTPM]":"10118.8","Tissue RNA - epididymis [nTPM]":"12166.4","Tissue RNA - esophagus [nTPM]":"23137.6","Tissue RNA - fallopian tube [nTPM]":"10414.1","Tissue RNA - gallbladder [nTPM]":"8134.8","Tissue RNA - heart muscle [nTPM]":"231090.6","Tissue RNA - hippocampal formation [nTPM]":"101700.1","Tissue RNA - hypothalamus [nTPM]":"98402.0","Tissue RNA - kidney [nTPM]":"135745.7","Tissue RNA - liver [nTPM]":"93934.0","Tissue RNA - lung [nTPM]":"11738.0","Tissue RNA - lymph node [nTPM]":"7309.6","Tissue RNA - medulla oblongata [nTPM]":"111323.1","Tissue RNA - midbrain [nTPM]":"103274.0","Tissue RNA - ovary [nTPM]":"9356.4","Tissue RNA - pancreas [nTPM]":"21307.1","Tissue RNA - parathyroid gland [nTPM]":"30833.6","Tissue RNA - pituitary gland [nTPM]":"18098.1","Tissue RNA - placenta [nTPM]":"9332.4","Tissue RNA - pons [nTPM]":"106050.0","Tissue RNA - prostate [nTPM]":"25270.8","Tissue RNA - rectum [nTPM]":"25404.7","Tissue RNA - retina [nTPM]":"14193.4","Tissue RNA - salivary gland [nTPM]":"21229.0","Tissue RNA - seminal vesicle [nTPM]":"16620.0","Tissue RNA - skeletal muscle [nTPM]":"98348.0","Tissue RNA - skin 1 [nTPM]":"28350.1","Tissue RNA - small intestine [nTPM]":"31017.2","Tissue RNA - smooth muscle [nTPM]":"10682.4","Tissue RNA - spinal cord [nTPM]":"91790.3","Tissue RNA - spleen [nTPM]":"14201.4","Tissue RNA - stomach 1 [nTPM]":"41772.3","Tissue RNA - testis [nTPM]":"19009.4","Tissue RNA - thalamus [nTPM]":"106894.6","Tissue RNA - thymus [nTPM]":"5959.0","Tissue RNA - thyroid gland [nTPM]":"20136.7","Tissue RNA - tongue [nTPM]":"138793.4","Tissue RNA - tonsil [nTPM]":"9366.6","Tissue RNA - urinary bladder [nTPM]":"19763.5","Tissue RNA - vagina [nTPM]":"13535.9","Tissue RNA - white matter [nTPM]":"91700.3","Cell RNA - A-431 [nTPM]":"6374.2","Cell RNA - A549 [nTPM]":"7329.2","Cell RNA - AF22 [nTPM]":"11033.5","Cell RNA - AN3-CA [nTPM]":"15732.2","Cell RNA - ASC diff [nTPM]":"21484.7","Cell RNA - ASC TERT1 [nTPM]":"8772.8","Cell RNA - BEWO [nTPM]":"6020.3","Cell RNA - BJ [nTPM]":"8032.3","Cell RNA - BJ hTERT+ [nTPM]":"4753.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3111.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4736.6","Cell RNA - CACO-2 [nTPM]":"9884.1","Cell RNA - CAPAN-2 [nTPM]":"9176.0","Cell RNA - Daudi [nTPM]":"14020.9","Cell RNA - EFO-21 [nTPM]":"3392.6","Cell RNA - fHDF\/TERT166 [nTPM]":"6719.8","Cell RNA - GAMG [nTPM]":"3380.0","Cell RNA - HaCaT [nTPM]":"16891.6","Cell RNA - HAP1 [nTPM]":"1769.9","Cell RNA - HBEC3-KT [nTPM]":"9653.6","Cell RNA - HBF TERT88 [nTPM]":"5455.7","Cell RNA - HDLM-2 [nTPM]":"4794.4","Cell RNA - HEK 293 [nTPM]":"7644.1","Cell RNA - HEL [nTPM]":"7478.3","Cell RNA - HeLa [nTPM]":"47821.5","Cell RNA - Hep G2 [nTPM]":"16704.0","Cell RNA - HHSteC [nTPM]":"4327.8","Cell RNA - HL-60 [nTPM]":"4505.2","Cell RNA - HMC-1 [nTPM]":"9419.7","Cell RNA - HSkMC [nTPM]":"8504.4","Cell RNA - hTCEpi [nTPM]":"13400.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3422.1","Cell RNA - hTERT-HME1 [nTPM]":"5046.7","Cell RNA - hTERT-RPE1 [nTPM]":"10915.4","Cell RNA - HUVEC TERT2 [nTPM]":"5848.3","Cell RNA - JURKAT [nTPM]":"7900.3","Cell RNA - K-562 [nTPM]":"6047.2","Cell RNA - Karpas-707 [nTPM]":"13759.0","Cell RNA - LHCN-M2 [nTPM]":"10367.7","Cell RNA - MCF7 [nTPM]":"12916.5","Cell RNA - MOLT-4 [nTPM]":"4589.9","Cell RNA - NB-4 [nTPM]":"25941.9","Cell RNA - NTERA-2 [nTPM]":"2461.0","Cell RNA - OE19 [nTPM]":"9979.3","Cell RNA - PC-3 [nTPM]":"5226.1","Cell RNA - REH [nTPM]":"4852.9","Cell RNA - RH-30 [nTPM]":"3482.9","Cell RNA - RPMI-8226 [nTPM]":"10181.9","Cell RNA - RPTEC TERT1 [nTPM]":"19232.2","Cell RNA - RT4 [nTPM]":"10970.2","Cell RNA - SCLC-21H [nTPM]":"4917.9","Cell RNA - SH-SY5Y [nTPM]":"6797.0","Cell RNA - SiHa [nTPM]":"3741.8","Cell RNA - SK-BR-3 [nTPM]":"4032.3","Cell RNA - SK-MEL-30 [nTPM]":"8135.9","Cell RNA - SuSa [nTPM]":"15244.2","Cell RNA - T-47d [nTPM]":"8471.0","Cell RNA - THP-1 [nTPM]":"19585.6","Cell RNA - TIME [nTPM]":"9432.2","Cell RNA - U-138 MG [nTPM]":"5152.8","Cell RNA - U-2 OS [nTPM]":"8782.1","Cell RNA - U-2197 [nTPM]":"9756.5","Cell RNA - U-251 MG [nTPM]":"5388.8","Cell RNA - U-266\/70 [nTPM]":"5622.3","Cell RNA - U-266\/84 [nTPM]":"3881.6","Cell RNA - U-698 [nTPM]":"8183.5","Cell RNA - U-87 MG [nTPM]":"5151.5","Cell RNA - U-937 [nTPM]":"14362.6","Cell RNA - WM-115 [nTPM]":"3475.8","Blood RNA - basophil [nTPM]":"2863.0","Blood RNA - classical monocyte [nTPM]":"4714.1","Blood RNA - eosinophil [nTPM]":"2004.7","Blood RNA - gdT-cell [nTPM]":"1562.3","Blood RNA - intermediate monocyte [nTPM]":"1885.5","Blood RNA - MAIT T-cell [nTPM]":"1896.8","Blood RNA - memory B-cell [nTPM]":"2933.1","Blood RNA - memory CD4 T-cell [nTPM]":"1703.2","Blood RNA - memory CD8 T-cell [nTPM]":"1823.0","Blood RNA - myeloid DC [nTPM]":"1927.4","Blood RNA - naive B-cell [nTPM]":"3253.5","Blood RNA - naive CD4 T-cell [nTPM]":"2137.7","Blood RNA - naive CD8 T-cell [nTPM]":"2759.1","Blood RNA - neutrophil [nTPM]":"3629.6","Blood RNA - NK-cell [nTPM]":"2089.5","Blood RNA - non-classical monocyte [nTPM]":"1920.3","Blood RNA - plasmacytoid DC [nTPM]":"1612.4","Blood RNA - T-reg [nTPM]":"1186.9","Blood RNA - total PBMC [nTPM]":"2432.3","Brain RNA - amygdala [nTPM]":"106768.6","Brain RNA - basal ganglia [nTPM]":"100201.0","Brain RNA - cerebellum [nTPM]":"92217.9","Brain RNA - cerebral cortex [nTPM]":"189825.4","Brain RNA - hippocampal formation [nTPM]":"101700.1","Brain RNA - hypothalamus [nTPM]":"98402.0","Brain RNA - medulla oblongata [nTPM]":"111323.1","Brain RNA - midbrain [nTPM]":"103274.0","Brain RNA - pons [nTPM]":"106050.0","Brain RNA - spinal cord [nTPM]":"91790.3","Brain RNA - thalamus [nTPM]":"106894.6","Brain RNA - white matter [nTPM]":"91700.3","Single Cell Type RNA - Adipocytes [nTPM]":"2817.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"1910.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2767.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"9010.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8343.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9724.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21550.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14394.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"8643.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8027.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"98114.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"20354.3","Single Cell Type RNA - Club cells [nTPM]":"11786.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"16547.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"5698.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"25285.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"4368.9","Single Cell Type RNA - Ductal cells [nTPM]":"5152.0","Single Cell Type RNA - Early spermatids [nTPM]":"1929.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10274.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6922.4","Single Cell Type RNA - Endothelial cells [nTPM]":"7282.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6805.3","Single Cell Type RNA - Erythroid cells [nTPM]":"29321.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6670.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"5902.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8605.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"22503.2","Single Cell Type RNA - granulocytes [nTPM]":"2090.9","Single Cell Type RNA - Granulosa cells [nTPM]":"20302.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15810.3","Single Cell Type RNA - Hepatocytes [nTPM]":"44494.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19209.5","Single Cell Type RNA - Ionocytes [nTPM]":"11157.0","Single Cell Type RNA - Kupffer cells [nTPM]":"28166.3","Single Cell Type RNA - Langerhans cells [nTPM]":"5603.1","Single Cell Type RNA - Late spermatids [nTPM]":"9286.2","Single Cell Type RNA - Leydig cells [nTPM]":"11579.8","Single Cell Type RNA - Macrophages [nTPM]":"7637.7","Single Cell Type RNA - Melanocytes [nTPM]":"5553.1","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"9746.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"6001.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5901.3","Single Cell Type RNA - Paneth cells [nTPM]":"16542.9","Single Cell Type RNA - Peritubular cells [nTPM]":"7809.0","Single Cell Type RNA - Plasma cells [nTPM]":"8204.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6813.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"47697.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"33390.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6427.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"12142.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15068.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7967.9","Single Cell Type RNA - Spermatocytes [nTPM]":"11927.7","Single Cell Type RNA - Spermatogonia [nTPM]":"12469.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17772.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8480.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"7584.6","Single Cell Type RNA - Theca cells [nTPM]":"21335.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"22667.3","Single Cell Type RNA - Urothelial cells [nTPM]":"15127.4"},{"Gene":"MT-ND2","Gene synonym":["MTND2","NAD2","ND2"],"Ensembl":"ENSG00000198763","Gene description":"Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2","Uniprot":["P03891"],"Chromosome":"MT","Position":"4470-5511","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Alzheimer disease","Amyloidosis","Disease variant","Leber hereditary optic neuropathy","Leigh syndrome","Neurodegeneration","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"101525.8","heart muscle":"130517.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"77734.8","Proximal enterocytes":"33797.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"16754.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"granulocytes":"16754.8"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"23544.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Tissue RNA - adipose tissue [nTPM]":"25741.8","Tissue RNA - adrenal gland [nTPM]":"33190.5","Tissue RNA - amygdala [nTPM]":"71860.8","Tissue RNA - appendix [nTPM]":"2728.1","Tissue RNA - basal ganglia [nTPM]":"75185.8","Tissue RNA - bone marrow [nTPM]":"2871.9","Tissue RNA - breast [nTPM]":"21730.1","Tissue RNA - cerebellum [nTPM]":"67030.8","Tissue RNA - cerebral cortex [nTPM]":"101525.8","Tissue RNA - cervix [nTPM]":"7501.8","Tissue RNA - choroid plexus [nTPM]":"71811.2","Tissue RNA - colon [nTPM]":"22574.5","Tissue RNA - duodenum [nTPM]":"7339.4","Tissue RNA - endometrium 1 [nTPM]":"7298.5","Tissue RNA - epididymis [nTPM]":"8093.3","Tissue RNA - esophagus [nTPM]":"11090.4","Tissue RNA - fallopian tube [nTPM]":"9270.8","Tissue RNA - gallbladder [nTPM]":"2863.6","Tissue RNA - heart muscle [nTPM]":"130517.4","Tissue RNA - hippocampal formation [nTPM]":"67583.8","Tissue RNA - hypothalamus [nTPM]":"74656.1","Tissue RNA - kidney [nTPM]":"57055.4","Tissue RNA - liver [nTPM]":"53965.1","Tissue RNA - lung [nTPM]":"9461.4","Tissue RNA - lymph node [nTPM]":"2469.7","Tissue RNA - medulla oblongata [nTPM]":"81497.3","Tissue RNA - midbrain [nTPM]":"77858.3","Tissue RNA - ovary [nTPM]":"7800.1","Tissue RNA - pancreas [nTPM]":"20642.6","Tissue RNA - parathyroid gland [nTPM]":"9848.0","Tissue RNA - pituitary gland [nTPM]":"12388.5","Tissue RNA - placenta [nTPM]":"5446.8","Tissue RNA - pons [nTPM]":"84069.6","Tissue RNA - prostate [nTPM]":"17166.0","Tissue RNA - rectum [nTPM]":"8141.9","Tissue RNA - retina [nTPM]":"5436.2","Tissue RNA - salivary gland [nTPM]":"13468.5","Tissue RNA - seminal vesicle [nTPM]":"5444.8","Tissue RNA - skeletal muscle [nTPM]":"45903.7","Tissue RNA - skin 1 [nTPM]":"15500.0","Tissue RNA - small intestine [nTPM]":"20333.4","Tissue RNA - smooth muscle [nTPM]":"3554.4","Tissue RNA - spinal cord [nTPM]":"65578.7","Tissue RNA - spleen [nTPM]":"8952.9","Tissue RNA - stomach 1 [nTPM]":"31183.1","Tissue RNA - testis [nTPM]":"11451.9","Tissue RNA - thalamus [nTPM]":"75256.7","Tissue RNA - thymus [nTPM]":"2049.2","Tissue RNA - thyroid gland [nTPM]":"10704.5","Tissue RNA - tongue [nTPM]":"50400.1","Tissue RNA - tonsil [nTPM]":"2830.9","Tissue RNA - urinary bladder [nTPM]":"14131.4","Tissue RNA - vagina [nTPM]":"8428.2","Tissue RNA - white matter [nTPM]":"66998.7","Cell RNA - A-431 [nTPM]":"2964.9","Cell RNA - A549 [nTPM]":"3166.9","Cell RNA - AF22 [nTPM]":"2774.5","Cell RNA - AN3-CA [nTPM]":"4699.2","Cell RNA - ASC diff [nTPM]":"9795.6","Cell RNA - ASC TERT1 [nTPM]":"1730.7","Cell RNA - BEWO [nTPM]":"2618.5","Cell RNA - BJ [nTPM]":"2678.9","Cell RNA - BJ hTERT+ [nTPM]":"669.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"703.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"875.8","Cell RNA - CACO-2 [nTPM]":"4014.2","Cell RNA - CAPAN-2 [nTPM]":"3860.6","Cell RNA - Daudi [nTPM]":"4185.9","Cell RNA - EFO-21 [nTPM]":"2486.9","Cell RNA - fHDF\/TERT166 [nTPM]":"1936.7","Cell RNA - GAMG [nTPM]":"1150.4","Cell RNA - HaCaT [nTPM]":"5147.5","Cell RNA - HAP1 [nTPM]":"444.4","Cell RNA - HBEC3-KT [nTPM]":"3349.6","Cell RNA - HBF TERT88 [nTPM]":"1504.2","Cell RNA - HDLM-2 [nTPM]":"3675.8","Cell RNA - HEK 293 [nTPM]":"2270.9","Cell RNA - HEL [nTPM]":"4845.1","Cell RNA - HeLa [nTPM]":"23544.1","Cell RNA - Hep G2 [nTPM]":"6585.1","Cell RNA - HHSteC [nTPM]":"1999.7","Cell RNA - HL-60 [nTPM]":"4760.9","Cell RNA - HMC-1 [nTPM]":"5392.4","Cell RNA - HSkMC [nTPM]":"2886.1","Cell RNA - hTCEpi [nTPM]":"5969.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1726.7","Cell RNA - hTERT-HME1 [nTPM]":"1692.0","Cell RNA - hTERT-RPE1 [nTPM]":"2488.5","Cell RNA - HUVEC TERT2 [nTPM]":"1049.4","Cell RNA - JURKAT [nTPM]":"2269.3","Cell RNA - K-562 [nTPM]":"3606.2","Cell RNA - Karpas-707 [nTPM]":"3978.3","Cell RNA - LHCN-M2 [nTPM]":"1701.5","Cell RNA - MCF7 [nTPM]":"3480.4","Cell RNA - MOLT-4 [nTPM]":"2711.2","Cell RNA - NB-4 [nTPM]":"7603.4","Cell RNA - NTERA-2 [nTPM]":"1396.2","Cell RNA - OE19 [nTPM]":"3068.2","Cell RNA - PC-3 [nTPM]":"2045.4","Cell RNA - REH [nTPM]":"2352.3","Cell RNA - RH-30 [nTPM]":"1554.8","Cell RNA - RPMI-8226 [nTPM]":"3525.9","Cell RNA - RPTEC TERT1 [nTPM]":"5071.4","Cell RNA - RT4 [nTPM]":"4465.8","Cell RNA - SCLC-21H [nTPM]":"1728.4","Cell RNA - SH-SY5Y [nTPM]":"2059.3","Cell RNA - SiHa [nTPM]":"1159.0","Cell RNA - SK-BR-3 [nTPM]":"3501.0","Cell RNA - SK-MEL-30 [nTPM]":"4372.7","Cell RNA - SuSa [nTPM]":"4402.7","Cell RNA - T-47d [nTPM]":"5412.1","Cell RNA - THP-1 [nTPM]":"5417.8","Cell RNA - TIME [nTPM]":"3333.0","Cell RNA - U-138 MG [nTPM]":"2606.6","Cell RNA - U-2 OS [nTPM]":"3230.5","Cell RNA - U-2197 [nTPM]":"3719.5","Cell RNA - U-251 MG [nTPM]":"3483.2","Cell RNA - U-266\/70 [nTPM]":"2577.9","Cell RNA - U-266\/84 [nTPM]":"2356.8","Cell RNA - U-698 [nTPM]":"3637.4","Cell RNA - U-87 MG [nTPM]":"1695.0","Cell RNA - U-937 [nTPM]":"4006.5","Cell RNA - WM-115 [nTPM]":"1196.1","Blood RNA - basophil [nTPM]":"16754.8","Blood RNA - classical monocyte [nTPM]":"1658.1","Blood RNA - eosinophil [nTPM]":"2709.0","Blood RNA - gdT-cell [nTPM]":"872.0","Blood RNA - intermediate monocyte [nTPM]":"1066.1","Blood RNA - MAIT T-cell [nTPM]":"1373.3","Blood RNA - memory B-cell [nTPM]":"1568.7","Blood RNA - memory CD4 T-cell [nTPM]":"1012.2","Blood RNA - memory CD8 T-cell [nTPM]":"1099.7","Blood RNA - myeloid DC [nTPM]":"632.5","Blood RNA - naive B-cell [nTPM]":"1625.8","Blood RNA - naive CD4 T-cell [nTPM]":"1212.2","Blood RNA - naive CD8 T-cell [nTPM]":"1558.3","Blood RNA - neutrophil [nTPM]":"2355.9","Blood RNA - NK-cell [nTPM]":"1158.8","Blood RNA - non-classical monocyte [nTPM]":"1341.7","Blood RNA - plasmacytoid DC [nTPM]":"1171.9","Blood RNA - T-reg [nTPM]":"716.1","Blood RNA - total PBMC [nTPM]":"804.2","Brain RNA - amygdala [nTPM]":"71860.8","Brain RNA - basal ganglia [nTPM]":"75185.8","Brain RNA - cerebellum [nTPM]":"67030.8","Brain RNA - cerebral cortex [nTPM]":"101525.8","Brain RNA - hippocampal formation [nTPM]":"67583.8","Brain RNA - hypothalamus [nTPM]":"74656.1","Brain RNA - medulla oblongata [nTPM]":"81497.3","Brain RNA - midbrain [nTPM]":"77858.3","Brain RNA - pons [nTPM]":"84069.6","Brain RNA - spinal cord [nTPM]":"65578.7","Brain RNA - thalamus [nTPM]":"75256.7","Brain RNA - white matter [nTPM]":"66998.7","Single Cell Type RNA - Adipocytes [nTPM]":"1855.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"919.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"759.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"3886.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2666.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7962.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3116.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2155.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"2560.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3948.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"77734.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"10211.5","Single Cell Type RNA - Club cells [nTPM]":"2425.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"6232.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"2313.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"13115.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1807.8","Single Cell Type RNA - Ductal cells [nTPM]":"1793.7","Single Cell Type RNA - Early spermatids [nTPM]":"1314.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4100.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2322.6","Single Cell Type RNA - Endothelial cells [nTPM]":"4025.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3175.3","Single Cell Type RNA - Erythroid cells [nTPM]":"10585.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3677.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2629.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2366.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5225.2","Single Cell Type RNA - granulocytes [nTPM]":"1865.9","Single Cell Type RNA - Granulosa cells [nTPM]":"7033.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9394.0","Single Cell Type RNA - Hepatocytes [nTPM]":"19067.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10974.6","Single Cell Type RNA - Ionocytes [nTPM]":"1947.0","Single Cell Type RNA - Kupffer cells [nTPM]":"14566.9","Single Cell Type RNA - Langerhans cells [nTPM]":"1814.8","Single Cell Type RNA - Late spermatids [nTPM]":"6327.6","Single Cell Type RNA - Leydig cells [nTPM]":"9064.4","Single Cell Type RNA - Macrophages [nTPM]":"3148.2","Single Cell Type RNA - Melanocytes [nTPM]":"1657.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"4768.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"3602.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2565.3","Single Cell Type RNA - Paneth cells [nTPM]":"9271.1","Single Cell Type RNA - Peritubular cells [nTPM]":"4538.8","Single Cell Type RNA - Plasma cells [nTPM]":"1959.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4228.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"33797.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12714.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3449.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"7283.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6341.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3547.2","Single Cell Type RNA - Spermatocytes [nTPM]":"5465.6","Single Cell Type RNA - Spermatogonia [nTPM]":"4872.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1826.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2455.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"3694.7","Single Cell Type RNA - Theca cells [nTPM]":"2538.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10272.4","Single Cell Type RNA - Urothelial cells [nTPM]":"7385.5"},{"Gene":"MT-ND3","Gene synonym":["MTND3","NAD3","ND3"],"Ensembl":"ENSG00000198840","Gene description":"Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3","Uniprot":["P03897"],"Chromosome":"MT","Position":"10059-10404","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Leigh syndrome","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"184151.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"37883.1","Proximal enterocytes":"23257.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"23280.2","HeLa":"21694.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063296"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA063296":"AB_2684978"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.63e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-3"},"Tissue RNA - adipose tissue [nTPM]":"31356.6","Tissue RNA - adrenal gland [nTPM]":"42036.1","Tissue RNA - amygdala [nTPM]":"79316.1","Tissue RNA - appendix [nTPM]":"3483.1","Tissue RNA - basal ganglia [nTPM]":"80070.8","Tissue RNA - bone marrow [nTPM]":"4077.5","Tissue RNA - breast [nTPM]":"25368.6","Tissue RNA - cerebellum [nTPM]":"75454.6","Tissue RNA - cerebral cortex [nTPM]":"124729.8","Tissue RNA - cervix [nTPM]":"8985.8","Tissue RNA - choroid plexus [nTPM]":"81148.8","Tissue RNA - colon [nTPM]":"26406.1","Tissue RNA - duodenum [nTPM]":"11478.9","Tissue RNA - endometrium 1 [nTPM]":"8410.1","Tissue RNA - epididymis [nTPM]":"8217.8","Tissue RNA - esophagus [nTPM]":"12712.6","Tissue RNA - fallopian tube [nTPM]":"10495.3","Tissue RNA - gallbladder [nTPM]":"3610.0","Tissue RNA - heart muscle [nTPM]":"184151.1","Tissue RNA - hippocampal formation [nTPM]":"75602.8","Tissue RNA - hypothalamus [nTPM]":"85299.8","Tissue RNA - kidney [nTPM]":"84244.0","Tissue RNA - liver [nTPM]":"72988.4","Tissue RNA - lung [nTPM]":"9018.3","Tissue RNA - lymph node [nTPM]":"3610.8","Tissue RNA - medulla oblongata [nTPM]":"89729.0","Tissue RNA - midbrain [nTPM]":"83678.9","Tissue RNA - ovary [nTPM]":"9439.2","Tissue RNA - pancreas [nTPM]":"26008.9","Tissue RNA - parathyroid gland [nTPM]":"14199.5","Tissue RNA - pituitary gland [nTPM]":"13387.4","Tissue RNA - placenta [nTPM]":"6281.1","Tissue RNA - pons [nTPM]":"85648.8","Tissue RNA - prostate [nTPM]":"23996.0","Tissue RNA - rectum [nTPM]":"10095.2","Tissue RNA - retina [nTPM]":"6318.4","Tissue RNA - salivary gland [nTPM]":"14787.5","Tissue RNA - seminal vesicle [nTPM]":"8355.4","Tissue RNA - skeletal muscle [nTPM]":"70313.2","Tissue RNA - skin 1 [nTPM]":"16879.7","Tissue RNA - small intestine [nTPM]":"21792.1","Tissue RNA - smooth muscle [nTPM]":"4960.7","Tissue RNA - spinal cord [nTPM]":"71704.7","Tissue RNA - spleen [nTPM]":"11407.9","Tissue RNA - stomach 1 [nTPM]":"36122.2","Tissue RNA - testis [nTPM]":"10815.9","Tissue RNA - thalamus [nTPM]":"84470.1","Tissue RNA - thymus [nTPM]":"3654.8","Tissue RNA - thyroid gland [nTPM]":"14626.9","Tissue RNA - tongue [nTPM]":"73367.5","Tissue RNA - tonsil [nTPM]":"3934.1","Tissue RNA - urinary bladder [nTPM]":"18841.5","Tissue RNA - vagina [nTPM]":"10373.7","Tissue RNA - white matter [nTPM]":"74059.9","Cell RNA - A-431 [nTPM]":"3324.0","Cell RNA - A549 [nTPM]":"5255.7","Cell RNA - AF22 [nTPM]":"3450.6","Cell RNA - AN3-CA [nTPM]":"3399.1","Cell RNA - ASC diff [nTPM]":"23280.2","Cell RNA - ASC TERT1 [nTPM]":"4613.0","Cell RNA - BEWO [nTPM]":"2871.7","Cell RNA - BJ [nTPM]":"2717.2","Cell RNA - BJ hTERT+ [nTPM]":"1592.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1441.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1616.6","Cell RNA - CACO-2 [nTPM]":"7973.2","Cell RNA - CAPAN-2 [nTPM]":"5004.1","Cell RNA - Daudi [nTPM]":"3408.8","Cell RNA - EFO-21 [nTPM]":"4095.7","Cell RNA - fHDF\/TERT166 [nTPM]":"3519.2","Cell RNA - GAMG [nTPM]":"2600.2","Cell RNA - HaCaT [nTPM]":"6710.1","Cell RNA - HAP1 [nTPM]":"1504.4","Cell RNA - HBEC3-KT [nTPM]":"5941.5","Cell RNA - HBF TERT88 [nTPM]":"2461.9","Cell RNA - HDLM-2 [nTPM]":"4945.3","Cell RNA - HEK 293 [nTPM]":"7153.7","Cell RNA - HEL [nTPM]":"3371.4","Cell RNA - HeLa [nTPM]":"21694.2","Cell RNA - Hep G2 [nTPM]":"13369.3","Cell RNA - HHSteC [nTPM]":"3629.0","Cell RNA - HL-60 [nTPM]":"5018.8","Cell RNA - HMC-1 [nTPM]":"4874.1","Cell RNA - HSkMC [nTPM]":"8076.0","Cell RNA - hTCEpi [nTPM]":"10704.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2416.7","Cell RNA - hTERT-HME1 [nTPM]":"2704.4","Cell RNA - hTERT-RPE1 [nTPM]":"8547.3","Cell RNA - HUVEC TERT2 [nTPM]":"2285.4","Cell RNA - JURKAT [nTPM]":"3853.4","Cell RNA - K-562 [nTPM]":"2711.1","Cell RNA - Karpas-707 [nTPM]":"3864.5","Cell RNA - LHCN-M2 [nTPM]":"2747.1","Cell RNA - MCF7 [nTPM]":"10748.2","Cell RNA - MOLT-4 [nTPM]":"2646.2","Cell RNA - NB-4 [nTPM]":"6609.3","Cell RNA - NTERA-2 [nTPM]":"1779.4","Cell RNA - OE19 [nTPM]":"9407.1","Cell RNA - PC-3 [nTPM]":"4824.1","Cell RNA - REH [nTPM]":"2262.5","Cell RNA - RH-30 [nTPM]":"3389.7","Cell RNA - RPMI-8226 [nTPM]":"3164.0","Cell RNA - RPTEC TERT1 [nTPM]":"8729.4","Cell RNA - RT4 [nTPM]":"8962.3","Cell RNA - SCLC-21H [nTPM]":"1417.0","Cell RNA - SH-SY5Y [nTPM]":"3058.9","Cell RNA - SiHa [nTPM]":"1310.8","Cell RNA - SK-BR-3 [nTPM]":"2587.7","Cell RNA - SK-MEL-30 [nTPM]":"5763.8","Cell RNA - SuSa [nTPM]":"8928.3","Cell RNA - T-47d [nTPM]":"6011.6","Cell RNA - THP-1 [nTPM]":"7960.5","Cell RNA - TIME [nTPM]":"3898.6","Cell RNA - U-138 MG [nTPM]":"2207.0","Cell RNA - U-2 OS [nTPM]":"3378.3","Cell RNA - U-2197 [nTPM]":"3876.8","Cell RNA - U-251 MG [nTPM]":"2982.9","Cell RNA - U-266\/70 [nTPM]":"1492.1","Cell RNA - U-266\/84 [nTPM]":"2128.5","Cell RNA - U-698 [nTPM]":"7735.7","Cell RNA - U-87 MG [nTPM]":"1794.0","Cell RNA - U-937 [nTPM]":"2976.6","Cell RNA - WM-115 [nTPM]":"1284.1","Blood RNA - basophil [nTPM]":"2263.7","Blood RNA - classical monocyte [nTPM]":"612.4","Blood RNA - eosinophil [nTPM]":"386.5","Blood RNA - gdT-cell [nTPM]":"336.6","Blood RNA - intermediate monocyte [nTPM]":"346.8","Blood RNA - MAIT T-cell [nTPM]":"441.9","Blood RNA - memory B-cell [nTPM]":"672.5","Blood RNA - memory CD4 T-cell [nTPM]":"393.0","Blood RNA - memory CD8 T-cell [nTPM]":"417.4","Blood RNA - myeloid DC [nTPM]":"321.5","Blood RNA - naive B-cell [nTPM]":"686.4","Blood RNA - naive CD4 T-cell [nTPM]":"568.4","Blood RNA - naive CD8 T-cell [nTPM]":"769.3","Blood RNA - neutrophil [nTPM]":"968.2","Blood RNA - NK-cell [nTPM]":"447.0","Blood RNA - non-classical monocyte [nTPM]":"335.5","Blood RNA - plasmacytoid DC [nTPM]":"312.1","Blood RNA - T-reg [nTPM]":"262.5","Blood RNA - total PBMC [nTPM]":"353.1","Brain RNA - amygdala [nTPM]":"79316.1","Brain RNA - basal ganglia [nTPM]":"80070.8","Brain RNA - cerebellum [nTPM]":"75454.6","Brain RNA - cerebral cortex [nTPM]":"124729.8","Brain RNA - hippocampal formation [nTPM]":"75602.8","Brain RNA - hypothalamus [nTPM]":"85299.8","Brain RNA - medulla oblongata [nTPM]":"89729.0","Brain RNA - midbrain [nTPM]":"83678.9","Brain RNA - pons [nTPM]":"85648.8","Brain RNA - spinal cord [nTPM]":"71704.7","Brain RNA - thalamus [nTPM]":"84470.1","Brain RNA - white matter [nTPM]":"74059.9","Single Cell Type RNA - Adipocytes [nTPM]":"4254.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"701.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"879.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"6320.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1987.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2507.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1722.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5384.4","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"3350.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5821.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"37883.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"9781.1","Single Cell Type RNA - Club cells [nTPM]":"1560.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"5041.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"5039.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"14324.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"1164.1","Single Cell Type RNA - Ductal cells [nTPM]":"1320.8","Single Cell Type RNA - Early spermatids [nTPM]":"1023.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11751.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6030.4","Single Cell Type RNA - Endothelial cells [nTPM]":"3302.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2852.4","Single Cell Type RNA - Erythroid cells [nTPM]":"14390.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2870.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"3063.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6039.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17552.8","Single Cell Type RNA - granulocytes [nTPM]":"1453.7","Single Cell Type RNA - Granulosa cells [nTPM]":"17373.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10407.8","Single Cell Type RNA - Hepatocytes [nTPM]":"20920.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11328.3","Single Cell Type RNA - Ionocytes [nTPM]":"870.8","Single Cell Type RNA - Kupffer cells [nTPM]":"16584.4","Single Cell Type RNA - Langerhans cells [nTPM]":"1757.6","Single Cell Type RNA - Late spermatids [nTPM]":"5643.0","Single Cell Type RNA - Leydig cells [nTPM]":"9133.7","Single Cell Type RNA - Macrophages [nTPM]":"4877.6","Single Cell Type RNA - Melanocytes [nTPM]":"1858.7","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"4964.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"2775.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2194.1","Single Cell Type RNA - Paneth cells [nTPM]":"9034.9","Single Cell Type RNA - Peritubular cells [nTPM]":"4865.3","Single Cell Type RNA - Plasma cells [nTPM]":"6343.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1554.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23257.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8457.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2113.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"7001.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6561.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3856.1","Single Cell Type RNA - Spermatocytes [nTPM]":"5442.6","Single Cell Type RNA - Spermatogonia [nTPM]":"3706.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3801.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1888.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"4844.1","Single Cell Type RNA - Theca cells [nTPM]":"3423.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10381.8","Single Cell Type RNA - Urothelial cells [nTPM]":"2314.6"},{"Gene":"MT-ND4","Gene synonym":["LHON","MTND4","NAD4","ND4"],"Ensembl":"ENSG00000198886","Gene description":"Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4","Uniprot":["P03905"],"Chromosome":"MT","Position":"10760-12137","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Dystonia","Leber hereditary optic neuropathy","MELAS syndrome","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"196536.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Cardiomyocytes":"253563.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"13456.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"41594.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053928"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA053928":"AB_2682313"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.76e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Tissue RNA - adipose tissue [nTPM]":"23701.9","Tissue RNA - adrenal gland [nTPM]":"43566.1","Tissue RNA - amygdala [nTPM]":"86386.5","Tissue RNA - appendix [nTPM]":"4193.8","Tissue RNA - basal ganglia [nTPM]":"83474.8","Tissue RNA - bone marrow [nTPM]":"3652.7","Tissue RNA - breast [nTPM]":"19363.5","Tissue RNA - cerebellum [nTPM]":"76852.9","Tissue RNA - cerebral cortex [nTPM]":"119139.4","Tissue RNA - cervix [nTPM]":"8711.6","Tissue RNA - choroid plexus [nTPM]":"100909.6","Tissue RNA - colon [nTPM]":"30312.4","Tissue RNA - duodenum [nTPM]":"11021.5","Tissue RNA - endometrium 1 [nTPM]":"10764.3","Tissue RNA - epididymis [nTPM]":"6795.9","Tissue RNA - esophagus [nTPM]":"15885.7","Tissue RNA - fallopian tube [nTPM]":"10624.6","Tissue RNA - gallbladder [nTPM]":"4622.9","Tissue RNA - heart muscle [nTPM]":"196536.0","Tissue RNA - hippocampal formation [nTPM]":"81116.7","Tissue RNA - hypothalamus [nTPM]":"85290.4","Tissue RNA - kidney [nTPM]":"76204.1","Tissue RNA - liver [nTPM]":"101401.1","Tissue RNA - lung [nTPM]":"11855.8","Tissue RNA - lymph node [nTPM]":"3820.4","Tissue RNA - medulla oblongata [nTPM]":"102081.7","Tissue RNA - midbrain [nTPM]":"90689.2","Tissue RNA - ovary [nTPM]":"8957.6","Tissue RNA - pancreas [nTPM]":"21476.2","Tissue RNA - parathyroid gland [nTPM]":"15709.9","Tissue RNA - pituitary gland [nTPM]":"12834.3","Tissue RNA - placenta [nTPM]":"7692.4","Tissue RNA - pons [nTPM]":"97098.9","Tissue RNA - prostate [nTPM]":"22214.5","Tissue RNA - rectum [nTPM]":"15007.9","Tissue RNA - retina [nTPM]":"14112.1","Tissue RNA - salivary gland [nTPM]":"17508.5","Tissue RNA - seminal vesicle [nTPM]":"11691.2","Tissue RNA - skeletal muscle [nTPM]":"61489.1","Tissue RNA - skin 1 [nTPM]":"18268.8","Tissue RNA - small intestine [nTPM]":"25046.6","Tissue RNA - smooth muscle [nTPM]":"7116.7","Tissue RNA - spinal cord [nTPM]":"75024.9","Tissue RNA - spleen [nTPM]":"12782.7","Tissue RNA - stomach 1 [nTPM]":"39594.1","Tissue RNA - testis [nTPM]":"13571.1","Tissue RNA - thalamus [nTPM]":"91494.4","Tissue RNA - thymus [nTPM]":"3233.7","Tissue RNA - thyroid gland [nTPM]":"14785.3","Tissue RNA - tongue [nTPM]":"70605.7","Tissue RNA - tonsil [nTPM]":"4913.1","Tissue RNA - urinary bladder [nTPM]":"19417.4","Tissue RNA - vagina [nTPM]":"10309.3","Tissue RNA - white matter [nTPM]":"74806.7","Cell RNA - A-431 [nTPM]":"4251.7","Cell RNA - A549 [nTPM]":"4285.9","Cell RNA - AF22 [nTPM]":"5449.6","Cell RNA - AN3-CA [nTPM]":"8075.1","Cell RNA - ASC diff [nTPM]":"12523.6","Cell RNA - ASC TERT1 [nTPM]":"3123.1","Cell RNA - BEWO [nTPM]":"3808.6","Cell RNA - BJ [nTPM]":"4184.0","Cell RNA - BJ hTERT+ [nTPM]":"1603.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"958.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1834.2","Cell RNA - CACO-2 [nTPM]":"6555.4","Cell RNA - CAPAN-2 [nTPM]":"4688.4","Cell RNA - Daudi [nTPM]":"7428.4","Cell RNA - EFO-21 [nTPM]":"3608.7","Cell RNA - fHDF\/TERT166 [nTPM]":"3590.8","Cell RNA - GAMG [nTPM]":"1396.3","Cell RNA - HaCaT [nTPM]":"7685.0","Cell RNA - HAP1 [nTPM]":"496.1","Cell RNA - HBEC3-KT [nTPM]":"6777.9","Cell RNA - HBF TERT88 [nTPM]":"1691.7","Cell RNA - HDLM-2 [nTPM]":"4330.2","Cell RNA - HEK 293 [nTPM]":"2654.6","Cell RNA - HEL [nTPM]":"4592.7","Cell RNA - HeLa [nTPM]":"41594.9","Cell RNA - Hep G2 [nTPM]":"11166.3","Cell RNA - HHSteC [nTPM]":"1884.9","Cell RNA - HL-60 [nTPM]":"4672.8","Cell RNA - HMC-1 [nTPM]":"5223.9","Cell RNA - HSkMC [nTPM]":"5330.2","Cell RNA - hTCEpi [nTPM]":"7007.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1403.3","Cell RNA - hTERT-HME1 [nTPM]":"4977.9","Cell RNA - hTERT-RPE1 [nTPM]":"8925.4","Cell RNA - HUVEC TERT2 [nTPM]":"2344.4","Cell RNA - JURKAT [nTPM]":"3683.1","Cell RNA - K-562 [nTPM]":"3908.9","Cell RNA - Karpas-707 [nTPM]":"8930.2","Cell RNA - LHCN-M2 [nTPM]":"3461.9","Cell RNA - MCF7 [nTPM]":"9508.0","Cell RNA - MOLT-4 [nTPM]":"1848.1","Cell RNA - NB-4 [nTPM]":"10481.0","Cell RNA - NTERA-2 [nTPM]":"1551.2","Cell RNA - OE19 [nTPM]":"3650.3","Cell RNA - PC-3 [nTPM]":"2876.4","Cell RNA - REH [nTPM]":"2481.0","Cell RNA - RH-30 [nTPM]":"1712.1","Cell RNA - RPMI-8226 [nTPM]":"4518.2","Cell RNA - RPTEC TERT1 [nTPM]":"6770.1","Cell RNA - RT4 [nTPM]":"8938.3","Cell RNA - SCLC-21H [nTPM]":"1999.0","Cell RNA - SH-SY5Y [nTPM]":"2694.8","Cell RNA - SiHa [nTPM]":"2434.3","Cell RNA - SK-BR-3 [nTPM]":"7967.3","Cell RNA - SK-MEL-30 [nTPM]":"4267.8","Cell RNA - SuSa [nTPM]":"9600.3","Cell RNA - T-47d [nTPM]":"5601.2","Cell RNA - THP-1 [nTPM]":"10888.7","Cell RNA - TIME [nTPM]":"6532.2","Cell RNA - U-138 MG [nTPM]":"3851.7","Cell RNA - U-2 OS [nTPM]":"3726.9","Cell RNA - U-2197 [nTPM]":"5232.7","Cell RNA - U-251 MG [nTPM]":"3330.8","Cell RNA - U-266\/70 [nTPM]":"5307.6","Cell RNA - U-266\/84 [nTPM]":"2292.6","Cell RNA - U-698 [nTPM]":"3407.7","Cell RNA - U-87 MG [nTPM]":"2514.1","Cell RNA - U-937 [nTPM]":"7881.4","Cell RNA - WM-115 [nTPM]":"2100.8","Blood RNA - basophil [nTPM]":"13456.8","Blood RNA - classical monocyte [nTPM]":"3334.1","Blood RNA - eosinophil [nTPM]":"7103.1","Blood RNA - gdT-cell [nTPM]":"1902.0","Blood RNA - intermediate monocyte [nTPM]":"2192.8","Blood RNA - MAIT T-cell [nTPM]":"2614.3","Blood RNA - memory B-cell [nTPM]":"3555.5","Blood RNA - memory CD4 T-cell [nTPM]":"2129.5","Blood RNA - memory CD8 T-cell [nTPM]":"2285.7","Blood RNA - myeloid DC [nTPM]":"1616.0","Blood RNA - naive B-cell [nTPM]":"3624.4","Blood RNA - naive CD4 T-cell [nTPM]":"2452.9","Blood RNA - naive CD8 T-cell [nTPM]":"3095.1","Blood RNA - neutrophil [nTPM]":"2513.1","Blood RNA - NK-cell [nTPM]":"2106.5","Blood RNA - non-classical monocyte [nTPM]":"2329.2","Blood RNA - plasmacytoid DC [nTPM]":"2112.6","Blood RNA - T-reg [nTPM]":"1668.2","Blood RNA - total PBMC [nTPM]":"1840.0","Brain RNA - amygdala [nTPM]":"86386.5","Brain RNA - basal ganglia [nTPM]":"83474.8","Brain RNA - cerebellum [nTPM]":"76852.9","Brain RNA - cerebral cortex [nTPM]":"119139.4","Brain RNA - hippocampal formation [nTPM]":"81116.7","Brain RNA - hypothalamus [nTPM]":"85290.4","Brain RNA - medulla oblongata [nTPM]":"102081.7","Brain RNA - midbrain [nTPM]":"90689.2","Brain RNA - pons [nTPM]":"97098.9","Brain RNA - spinal cord [nTPM]":"75024.9","Brain RNA - thalamus [nTPM]":"91494.4","Brain RNA - white matter [nTPM]":"74806.7","Single Cell Type RNA - Adipocytes [nTPM]":"3065.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"1269.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1516.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"6183.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4404.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9073.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7719.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2713.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"6210.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6965.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"253563.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"15377.3","Single Cell Type RNA - Club cells [nTPM]":"4975.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"12806.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"4005.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"20185.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"2435.8","Single Cell Type RNA - Ductal cells [nTPM]":"2924.2","Single Cell Type RNA - Early spermatids [nTPM]":"1109.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6731.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4298.6","Single Cell Type RNA - Endothelial cells [nTPM]":"9316.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5090.0","Single Cell Type RNA - Erythroid cells [nTPM]":"20898.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4058.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"5843.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5601.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11920.4","Single Cell Type RNA - granulocytes [nTPM]":"2188.6","Single Cell Type RNA - Granulosa cells [nTPM]":"15486.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13931.3","Single Cell Type RNA - Hepatocytes [nTPM]":"35046.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14557.8","Single Cell Type RNA - Ionocytes [nTPM]":"5771.7","Single Cell Type RNA - Kupffer cells [nTPM]":"22254.8","Single Cell Type RNA - Langerhans cells [nTPM]":"3452.7","Single Cell Type RNA - Late spermatids [nTPM]":"5132.5","Single Cell Type RNA - Leydig cells [nTPM]":"8834.9","Single Cell Type RNA - Macrophages [nTPM]":"4749.3","Single Cell Type RNA - Melanocytes [nTPM]":"3799.3","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"6280.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"4212.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3710.0","Single Cell Type RNA - Paneth cells [nTPM]":"12363.2","Single Cell Type RNA - Peritubular cells [nTPM]":"5788.3","Single Cell Type RNA - Plasma cells [nTPM]":"3409.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5872.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"28978.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17714.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4527.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6310.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8264.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7732.9","Single Cell Type RNA - Spermatocytes [nTPM]":"6461.4","Single Cell Type RNA - Spermatogonia [nTPM]":"6003.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3008.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4937.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"5125.3","Single Cell Type RNA - Theca cells [nTPM]":"7671.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15595.2","Single Cell Type RNA - Urothelial cells [nTPM]":"11405.7"},{"Gene":"MT-ND4L","Gene synonym":["MTND4L","NAD4L","ND4L"],"Ensembl":"ENSG00000212907","Gene description":"Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L","Uniprot":["P03901"],"Chromosome":"MT","Position":"10470-10766","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Leber hereditary optic neuropathy","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"132930.7","heart muscle":"145078.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cardiomyocytes":"30444.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"50775.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA075648"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"HPA075648":"AB_2686760"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.47e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"},"Tissue RNA - adipose tissue [nTPM]":"20104.7","Tissue RNA - adrenal gland [nTPM]":"29874.0","Tissue RNA - amygdala [nTPM]":"85794.9","Tissue RNA - appendix [nTPM]":"4122.5","Tissue RNA - basal ganglia [nTPM]":"86270.4","Tissue RNA - bone marrow [nTPM]":"3115.3","Tissue RNA - breast [nTPM]":"14930.3","Tissue RNA - cerebellum [nTPM]":"82985.5","Tissue RNA - cerebral cortex [nTPM]":"132930.7","Tissue RNA - cervix [nTPM]":"6880.0","Tissue RNA - choroid plexus [nTPM]":"93989.2","Tissue RNA - colon [nTPM]":"20616.6","Tissue RNA - duodenum [nTPM]":"9025.8","Tissue RNA - endometrium 1 [nTPM]":"7679.7","Tissue RNA - epididymis [nTPM]":"5976.7","Tissue RNA - esophagus [nTPM]":"10820.3","Tissue RNA - fallopian tube [nTPM]":"7752.4","Tissue RNA - gallbladder [nTPM]":"4365.8","Tissue RNA - heart muscle [nTPM]":"145078.7","Tissue RNA - hippocampal formation [nTPM]":"84214.9","Tissue RNA - hypothalamus [nTPM]":"90415.7","Tissue RNA - kidney [nTPM]":"46912.7","Tissue RNA - liver [nTPM]":"74928.5","Tissue RNA - lung [nTPM]":"8462.2","Tissue RNA - lymph node [nTPM]":"2787.1","Tissue RNA - medulla oblongata [nTPM]":"92948.1","Tissue RNA - midbrain [nTPM]":"87984.2","Tissue RNA - ovary [nTPM]":"6729.2","Tissue RNA - pancreas [nTPM]":"16038.2","Tissue RNA - parathyroid gland [nTPM]":"20410.6","Tissue RNA - pituitary gland [nTPM]":"9234.3","Tissue RNA - placenta [nTPM]":"5840.3","Tissue RNA - pons [nTPM]":"89012.2","Tissue RNA - prostate [nTPM]":"16438.2","Tissue RNA - rectum [nTPM]":"14044.5","Tissue RNA - retina [nTPM]":"15747.5","Tissue RNA - salivary gland [nTPM]":"12913.6","Tissue RNA - seminal vesicle [nTPM]":"12715.8","Tissue RNA - skeletal muscle [nTPM]":"58998.5","Tissue RNA - skin 1 [nTPM]":"13345.9","Tissue RNA - small intestine [nTPM]":"17015.9","Tissue RNA - smooth muscle [nTPM]":"6979.3","Tissue RNA - spinal cord [nTPM]":"79192.1","Tissue RNA - spleen [nTPM]":"7285.6","Tissue RNA - stomach 1 [nTPM]":"28192.3","Tissue RNA - testis [nTPM]":"9561.4","Tissue RNA - thalamus [nTPM]":"87700.1","Tissue RNA - thymus [nTPM]":"4435.4","Tissue RNA - thyroid gland [nTPM]":"11270.7","Tissue RNA - tongue [nTPM]":"103082.4","Tissue RNA - tonsil [nTPM]":"4852.1","Tissue RNA - urinary bladder [nTPM]":"15113.7","Tissue RNA - vagina [nTPM]":"7437.4","Tissue RNA - white matter [nTPM]":"83632.8","Cell RNA - A-431 [nTPM]":"4598.0","Cell RNA - A549 [nTPM]":"4121.5","Cell RNA - AF22 [nTPM]":"7308.1","Cell RNA - AN3-CA [nTPM]":"7468.2","Cell RNA - ASC diff [nTPM]":"25088.0","Cell RNA - ASC TERT1 [nTPM]":"5217.1","Cell RNA - BEWO [nTPM]":"3223.3","Cell RNA - BJ [nTPM]":"9523.0","Cell RNA - BJ hTERT+ [nTPM]":"2384.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1468.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2651.9","Cell RNA - CACO-2 [nTPM]":"6894.3","Cell RNA - CAPAN-2 [nTPM]":"4080.7","Cell RNA - Daudi [nTPM]":"11229.9","Cell RNA - EFO-21 [nTPM]":"3809.7","Cell RNA - fHDF\/TERT166 [nTPM]":"6497.0","Cell RNA - GAMG [nTPM]":"2387.4","Cell RNA - HaCaT [nTPM]":"8496.5","Cell RNA - HAP1 [nTPM]":"1155.8","Cell RNA - HBEC3-KT [nTPM]":"10210.3","Cell RNA - HBF TERT88 [nTPM]":"2895.1","Cell RNA - HDLM-2 [nTPM]":"4454.2","Cell RNA - HEK 293 [nTPM]":"4711.8","Cell RNA - HEL [nTPM]":"8095.9","Cell RNA - HeLa [nTPM]":"50775.4","Cell RNA - Hep G2 [nTPM]":"13024.1","Cell RNA - HHSteC [nTPM]":"3671.8","Cell RNA - HL-60 [nTPM]":"8429.4","Cell RNA - HMC-1 [nTPM]":"6965.0","Cell RNA - HSkMC [nTPM]":"9229.0","Cell RNA - hTCEpi [nTPM]":"10159.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2792.9","Cell RNA - hTERT-HME1 [nTPM]":"9675.2","Cell RNA - hTERT-RPE1 [nTPM]":"10923.1","Cell RNA - HUVEC TERT2 [nTPM]":"2983.6","Cell RNA - JURKAT [nTPM]":"5697.7","Cell RNA - K-562 [nTPM]":"4556.7","Cell RNA - Karpas-707 [nTPM]":"7771.2","Cell RNA - LHCN-M2 [nTPM]":"5412.1","Cell RNA - MCF7 [nTPM]":"8124.5","Cell RNA - MOLT-4 [nTPM]":"3199.8","Cell RNA - NB-4 [nTPM]":"10639.4","Cell RNA - NTERA-2 [nTPM]":"1846.3","Cell RNA - OE19 [nTPM]":"4811.8","Cell RNA - PC-3 [nTPM]":"4953.4","Cell RNA - REH [nTPM]":"1842.5","Cell RNA - RH-30 [nTPM]":"3155.8","Cell RNA - RPMI-8226 [nTPM]":"5025.1","Cell RNA - RPTEC TERT1 [nTPM]":"7636.0","Cell RNA - RT4 [nTPM]":"9464.9","Cell RNA - SCLC-21H [nTPM]":"2208.4","Cell RNA - SH-SY5Y [nTPM]":"2971.3","Cell RNA - SiHa [nTPM]":"4666.2","Cell RNA - SK-BR-3 [nTPM]":"7283.7","Cell RNA - SK-MEL-30 [nTPM]":"3197.8","Cell RNA - SuSa [nTPM]":"15599.0","Cell RNA - T-47d [nTPM]":"5199.9","Cell RNA - THP-1 [nTPM]":"10420.1","Cell RNA - TIME [nTPM]":"9592.2","Cell RNA - U-138 MG [nTPM]":"3792.1","Cell RNA - U-2 OS [nTPM]":"4708.5","Cell RNA - U-2197 [nTPM]":"5630.1","Cell RNA - U-251 MG [nTPM]":"3738.0","Cell RNA - U-266\/70 [nTPM]":"6985.1","Cell RNA - U-266\/84 [nTPM]":"3552.9","Cell RNA - U-698 [nTPM]":"6053.5","Cell RNA - U-87 MG [nTPM]":"2725.1","Cell RNA - U-937 [nTPM]":"11018.8","Cell RNA - WM-115 [nTPM]":"1816.1","Blood RNA - basophil [nTPM]":"16170.2","Blood RNA - classical monocyte [nTPM]":"4327.0","Blood RNA - eosinophil [nTPM]":"8286.8","Blood RNA - gdT-cell [nTPM]":"2536.0","Blood RNA - intermediate monocyte [nTPM]":"2849.6","Blood RNA - MAIT T-cell [nTPM]":"3435.6","Blood RNA - memory B-cell [nTPM]":"4233.2","Blood RNA - memory CD4 T-cell [nTPM]":"2723.9","Blood RNA - memory CD8 T-cell [nTPM]":"2939.9","Blood RNA - myeloid DC [nTPM]":"2282.7","Blood RNA - naive B-cell [nTPM]":"4618.7","Blood RNA - naive CD4 T-cell [nTPM]":"3206.8","Blood RNA - naive CD8 T-cell [nTPM]":"4006.1","Blood RNA - neutrophil [nTPM]":"2010.3","Blood RNA - NK-cell [nTPM]":"2906.4","Blood RNA - non-classical monocyte [nTPM]":"2817.9","Blood RNA - plasmacytoid DC [nTPM]":"2884.1","Blood RNA - T-reg [nTPM]":"2096.4","Blood RNA - total PBMC [nTPM]":"2551.4","Brain RNA - amygdala [nTPM]":"85794.9","Brain RNA - basal ganglia [nTPM]":"86270.4","Brain RNA - cerebellum [nTPM]":"82985.5","Brain RNA - cerebral cortex [nTPM]":"132930.7","Brain RNA - hippocampal formation [nTPM]":"84214.9","Brain RNA - hypothalamus [nTPM]":"90415.7","Brain RNA - medulla oblongata [nTPM]":"92948.1","Brain RNA - midbrain [nTPM]":"87984.2","Brain RNA - pons [nTPM]":"89012.2","Brain RNA - spinal cord [nTPM]":"79192.1","Brain RNA - thalamus [nTPM]":"87700.1","Brain RNA - white matter [nTPM]":"83632.8","Single Cell Type RNA - Adipocytes [nTPM]":"503.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"224.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"217.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2303.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"228.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"254.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"170.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5991.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"764.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"886.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"30444.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"1464.1","Single Cell Type RNA - Club cells [nTPM]":"438.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"323.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"449.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"1428.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"90.1","Single Cell Type RNA - Ductal cells [nTPM]":"152.9","Single Cell Type RNA - Early spermatids [nTPM]":"52.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"870.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"618.8","Single Cell Type RNA - Endothelial cells [nTPM]":"942.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"256.6","Single Cell Type RNA - Erythroid cells [nTPM]":"3302.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"342.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1129.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5335.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1186.3","Single Cell Type RNA - granulocytes [nTPM]":"479.3","Single Cell Type RNA - Granulosa cells [nTPM]":"1394.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1520.3","Single Cell Type RNA - Hepatocytes [nTPM]":"4413.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"727.8","Single Cell Type RNA - Ionocytes [nTPM]":"99.7","Single Cell Type RNA - Kupffer cells [nTPM]":"1977.9","Single Cell Type RNA - Langerhans cells [nTPM]":"193.5","Single Cell Type RNA - Late spermatids [nTPM]":"286.1","Single Cell Type RNA - Leydig cells [nTPM]":"417.2","Single Cell Type RNA - Macrophages [nTPM]":"1043.8","Single Cell Type RNA - Melanocytes [nTPM]":"256.1","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"312.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"133.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"284.5","Single Cell Type RNA - Paneth cells [nTPM]":"867.0","Single Cell Type RNA - Peritubular cells [nTPM]":"230.9","Single Cell Type RNA - Plasma cells [nTPM]":"4395.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"129.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1228.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"589.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"582.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"348.4","Single Cell Type RNA - Skeletal myocytes [nTPM]":"711.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1052.8","Single Cell Type RNA - Spermatocytes [nTPM]":"247.0","Single Cell Type RNA - Spermatogonia [nTPM]":"207.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5256.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"242.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1387.0","Single Cell Type RNA - Theca cells [nTPM]":"308.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"573.4","Single Cell Type RNA - Urothelial cells [nTPM]":"207.9"},{"Gene":"MT-ND5","Gene synonym":["MTND5","NAD5","ND5"],"Ensembl":"ENSG00000198786","Gene description":"Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5","Uniprot":["P03915"],"Chromosome":"MT","Position":"12337-14148","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Leber hereditary optic neuropathy","Leigh syndrome","MELAS syndrome","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"25147.7","heart muscle":"26116.9","skeletal muscle":"25697.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cardiomyocytes":"35040.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"10198.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.31e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.93e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Tissue RNA - adipose tissue [nTPM]":"5288.6","Tissue RNA - adrenal gland [nTPM]":"4777.7","Tissue RNA - amygdala [nTPM]":"18907.8","Tissue RNA - appendix [nTPM]":"1742.2","Tissue RNA - basal ganglia [nTPM]":"18307.4","Tissue RNA - bone marrow [nTPM]":"1525.5","Tissue RNA - breast [nTPM]":"2456.7","Tissue RNA - cerebellum [nTPM]":"14400.2","Tissue RNA - cerebral cortex [nTPM]":"21432.3","Tissue RNA - cervix [nTPM]":"1614.3","Tissue RNA - choroid plexus [nTPM]":"22368.1","Tissue RNA - colon [nTPM]":"4280.6","Tissue RNA - duodenum [nTPM]":"4135.2","Tissue RNA - endometrium 1 [nTPM]":"1972.7","Tissue RNA - epididymis [nTPM]":"2508.1","Tissue RNA - esophagus [nTPM]":"2717.8","Tissue RNA - fallopian tube [nTPM]":"3030.2","Tissue RNA - gallbladder [nTPM]":"2040.5","Tissue RNA - heart muscle [nTPM]":"26116.9","Tissue RNA - hippocampal formation [nTPM]":"16370.1","Tissue RNA - hypothalamus [nTPM]":"20521.2","Tissue RNA - kidney [nTPM]":"8014.5","Tissue RNA - liver [nTPM]":"10041.3","Tissue RNA - lung [nTPM]":"2683.6","Tissue RNA - lymph node [nTPM]":"1180.6","Tissue RNA - medulla oblongata [nTPM]":"25147.7","Tissue RNA - midbrain [nTPM]":"20794.2","Tissue RNA - ovary [nTPM]":"1886.3","Tissue RNA - pancreas [nTPM]":"2631.6","Tissue RNA - parathyroid gland [nTPM]":"4813.1","Tissue RNA - pituitary gland [nTPM]":"1528.8","Tissue RNA - placenta [nTPM]":"1691.5","Tissue RNA - pons [nTPM]":"23065.0","Tissue RNA - prostate [nTPM]":"2812.7","Tissue RNA - rectum [nTPM]":"2879.0","Tissue RNA - retina [nTPM]":"3264.8","Tissue RNA - salivary gland [nTPM]":"2819.2","Tissue RNA - seminal vesicle [nTPM]":"2163.8","Tissue RNA - skeletal muscle [nTPM]":"25697.4","Tissue RNA - skin 1 [nTPM]":"6657.3","Tissue RNA - small intestine [nTPM]":"4780.7","Tissue RNA - smooth muscle [nTPM]":"2643.7","Tissue RNA - spinal cord [nTPM]":"13881.7","Tissue RNA - spleen [nTPM]":"2014.4","Tissue RNA - stomach 1 [nTPM]":"6673.9","Tissue RNA - testis [nTPM]":"1678.5","Tissue RNA - thalamus [nTPM]":"21024.6","Tissue RNA - thymus [nTPM]":"794.7","Tissue RNA - thyroid gland [nTPM]":"2059.1","Tissue RNA - tongue [nTPM]":"19444.2","Tissue RNA - tonsil [nTPM]":"1541.4","Tissue RNA - urinary bladder [nTPM]":"3557.5","Tissue RNA - vagina [nTPM]":"1537.7","Tissue RNA - white matter [nTPM]":"13870.1","Cell RNA - A-431 [nTPM]":"1615.8","Cell RNA - A549 [nTPM]":"1671.5","Cell RNA - AF22 [nTPM]":"1998.7","Cell RNA - AN3-CA [nTPM]":"1937.9","Cell RNA - ASC diff [nTPM]":"5903.9","Cell RNA - ASC TERT1 [nTPM]":"1530.3","Cell RNA - BEWO [nTPM]":"1075.8","Cell RNA - BJ [nTPM]":"3208.3","Cell RNA - BJ hTERT+ [nTPM]":"492.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"355.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"583.1","Cell RNA - CACO-2 [nTPM]":"2472.6","Cell RNA - CAPAN-2 [nTPM]":"2051.0","Cell RNA - Daudi [nTPM]":"3865.3","Cell RNA - EFO-21 [nTPM]":"1590.5","Cell RNA - fHDF\/TERT166 [nTPM]":"1510.4","Cell RNA - GAMG [nTPM]":"397.3","Cell RNA - HaCaT [nTPM]":"3350.6","Cell RNA - HAP1 [nTPM]":"191.2","Cell RNA - HBEC3-KT [nTPM]":"1685.7","Cell RNA - HBF TERT88 [nTPM]":"583.4","Cell RNA - HDLM-2 [nTPM]":"2182.3","Cell RNA - HEK 293 [nTPM]":"1281.4","Cell RNA - HEL [nTPM]":"2840.4","Cell RNA - HeLa [nTPM]":"10198.2","Cell RNA - Hep G2 [nTPM]":"4239.2","Cell RNA - HHSteC [nTPM]":"678.8","Cell RNA - HL-60 [nTPM]":"2010.7","Cell RNA - HMC-1 [nTPM]":"2824.3","Cell RNA - HSkMC [nTPM]":"2305.4","Cell RNA - hTCEpi [nTPM]":"1315.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"401.6","Cell RNA - hTERT-HME1 [nTPM]":"951.8","Cell RNA - hTERT-RPE1 [nTPM]":"1933.5","Cell RNA - HUVEC TERT2 [nTPM]":"725.2","Cell RNA - JURKAT [nTPM]":"1233.3","Cell RNA - K-562 [nTPM]":"1056.8","Cell RNA - Karpas-707 [nTPM]":"1794.8","Cell RNA - LHCN-M2 [nTPM]":"1216.3","Cell RNA - MCF7 [nTPM]":"3046.1","Cell RNA - MOLT-4 [nTPM]":"757.3","Cell RNA - NB-4 [nTPM]":"2453.4","Cell RNA - NTERA-2 [nTPM]":"397.5","Cell RNA - OE19 [nTPM]":"910.2","Cell RNA - PC-3 [nTPM]":"903.0","Cell RNA - REH [nTPM]":"1432.9","Cell RNA - RH-30 [nTPM]":"938.2","Cell RNA - RPMI-8226 [nTPM]":"1668.7","Cell RNA - RPTEC TERT1 [nTPM]":"2083.2","Cell RNA - RT4 [nTPM]":"3132.2","Cell RNA - SCLC-21H [nTPM]":"595.0","Cell RNA - SH-SY5Y [nTPM]":"904.1","Cell RNA - SiHa [nTPM]":"1496.1","Cell RNA - SK-BR-3 [nTPM]":"2636.3","Cell RNA - SK-MEL-30 [nTPM]":"894.4","Cell RNA - SuSa [nTPM]":"3001.9","Cell RNA - T-47d [nTPM]":"1927.1","Cell RNA - THP-1 [nTPM]":"2979.2","Cell RNA - TIME [nTPM]":"5094.9","Cell RNA - U-138 MG [nTPM]":"2013.2","Cell RNA - U-2 OS [nTPM]":"1403.2","Cell RNA - U-2197 [nTPM]":"2409.7","Cell RNA - U-251 MG [nTPM]":"1271.9","Cell RNA - U-266\/70 [nTPM]":"678.8","Cell RNA - U-266\/84 [nTPM]":"1246.0","Cell RNA - U-698 [nTPM]":"1066.9","Cell RNA - U-87 MG [nTPM]":"1077.4","Cell RNA - U-937 [nTPM]":"1780.4","Cell RNA - WM-115 [nTPM]":"897.7","Blood RNA - basophil [nTPM]":"2851.8","Blood RNA - classical monocyte [nTPM]":"1521.7","Blood RNA - eosinophil [nTPM]":"874.2","Blood RNA - gdT-cell [nTPM]":"771.4","Blood RNA - intermediate monocyte [nTPM]":"980.3","Blood RNA - MAIT T-cell [nTPM]":"922.8","Blood RNA - memory B-cell [nTPM]":"979.1","Blood RNA - memory CD4 T-cell [nTPM]":"753.9","Blood RNA - memory CD8 T-cell [nTPM]":"839.2","Blood RNA - myeloid DC [nTPM]":"746.5","Blood RNA - naive B-cell [nTPM]":"1096.6","Blood RNA - naive CD4 T-cell [nTPM]":"729.2","Blood RNA - naive CD8 T-cell [nTPM]":"869.0","Blood RNA - neutrophil [nTPM]":"446.2","Blood RNA - NK-cell [nTPM]":"785.1","Blood RNA - non-classical monocyte [nTPM]":"1039.5","Blood RNA - plasmacytoid DC [nTPM]":"890.3","Blood RNA - T-reg [nTPM]":"628.6","Blood RNA - total PBMC [nTPM]":"492.0","Brain RNA - amygdala [nTPM]":"18907.8","Brain RNA - basal ganglia [nTPM]":"18307.4","Brain RNA - cerebellum [nTPM]":"14400.2","Brain RNA - cerebral cortex [nTPM]":"21432.3","Brain RNA - hippocampal formation [nTPM]":"16370.1","Brain RNA - hypothalamus [nTPM]":"20521.2","Brain RNA - medulla oblongata [nTPM]":"25147.7","Brain RNA - midbrain [nTPM]":"20794.2","Brain RNA - pons [nTPM]":"23065.0","Brain RNA - spinal cord [nTPM]":"13881.7","Brain RNA - thalamus [nTPM]":"21024.6","Brain RNA - white matter [nTPM]":"13870.1","Single Cell Type RNA - Adipocytes [nTPM]":"773.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"628.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"594.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1707.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"895.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1050.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1005.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3261.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1003.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1025.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"35040.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"2566.4","Single Cell Type RNA - Club cells [nTPM]":"934.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"1156.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"977.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"3181.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"283.7","Single Cell Type RNA - Ductal cells [nTPM]":"804.1","Single Cell Type RNA - Early spermatids [nTPM]":"109.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3130.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2025.6","Single Cell Type RNA - Endothelial cells [nTPM]":"1614.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"782.9","Single Cell Type RNA - Erythroid cells [nTPM]":"3776.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"936.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1437.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3609.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5212.8","Single Cell Type RNA - granulocytes [nTPM]":"862.1","Single Cell Type RNA - Granulosa cells [nTPM]":"2987.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2623.3","Single Cell Type RNA - Hepatocytes [nTPM]":"6597.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1776.8","Single Cell Type RNA - Ionocytes [nTPM]":"583.9","Single Cell Type RNA - Kupffer cells [nTPM]":"3664.2","Single Cell Type RNA - Langerhans cells [nTPM]":"661.9","Single Cell Type RNA - Late spermatids [nTPM]":"528.9","Single Cell Type RNA - Leydig cells [nTPM]":"1057.5","Single Cell Type RNA - Macrophages [nTPM]":"1364.5","Single Cell Type RNA - Melanocytes [nTPM]":"608.3","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1303.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"756.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1327.8","Single Cell Type RNA - Paneth cells [nTPM]":"2211.7","Single Cell Type RNA - Peritubular cells [nTPM]":"848.6","Single Cell Type RNA - Plasma cells [nTPM]":"2674.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"753.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4484.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2410.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1282.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"696.8","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1941.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1558.6","Single Cell Type RNA - Spermatocytes [nTPM]":"652.2","Single Cell Type RNA - Spermatogonia [nTPM]":"521.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3002.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"973.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1527.8","Single Cell Type RNA - Theca cells [nTPM]":"1560.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1650.5","Single Cell Type RNA - Urothelial cells [nTPM]":"1506.6"},{"Gene":"MT-ND6","Gene synonym":["MTND6","NAD6","ND6"],"Ensembl":"ENSG00000198695","Gene description":"Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6","Uniprot":["P03923"],"Chromosome":"MT","Position":"14149-14673","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Dystonia","Leber hereditary optic neuropathy","Leigh syndrome","MELAS syndrome","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"35802.7","skeletal muscle":"57879.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Cardiomyocytes":"15756.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"20826.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.02e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.91e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Tissue RNA - adipose tissue [nTPM]":"7945.8","Tissue RNA - adrenal gland [nTPM]":"6310.2","Tissue RNA - amygdala [nTPM]":"5769.7","Tissue RNA - appendix [nTPM]":"3186.7","Tissue RNA - basal ganglia [nTPM]":"3927.7","Tissue RNA - bone marrow [nTPM]":"3253.0","Tissue RNA - breast [nTPM]":"3096.2","Tissue RNA - cerebellum [nTPM]":"2199.5","Tissue RNA - cerebral cortex [nTPM]":"5682.5","Tissue RNA - cervix [nTPM]":"2191.3","Tissue RNA - choroid plexus [nTPM]":"13970.3","Tissue RNA - colon [nTPM]":"6452.8","Tissue RNA - duodenum [nTPM]":"7840.8","Tissue RNA - endometrium 1 [nTPM]":"3145.2","Tissue RNA - epididymis [nTPM]":"54.5","Tissue RNA - esophagus [nTPM]":"5822.6","Tissue RNA - fallopian tube [nTPM]":"5447.4","Tissue RNA - gallbladder [nTPM]":"3433.9","Tissue RNA - heart muscle [nTPM]":"35802.7","Tissue RNA - hippocampal formation [nTPM]":"4361.1","Tissue RNA - hypothalamus [nTPM]":"7820.0","Tissue RNA - kidney [nTPM]":"9569.5","Tissue RNA - liver [nTPM]":"11697.0","Tissue RNA - lung [nTPM]":"4598.5","Tissue RNA - lymph node [nTPM]":"2503.1","Tissue RNA - medulla oblongata [nTPM]":"13167.2","Tissue RNA - midbrain [nTPM]":"11029.3","Tissue RNA - ovary [nTPM]":"2126.9","Tissue RNA - pancreas [nTPM]":"4152.4","Tissue RNA - parathyroid gland [nTPM]":"69.3","Tissue RNA - pituitary gland [nTPM]":"1372.8","Tissue RNA - placenta [nTPM]":"953.0","Tissue RNA - pons [nTPM]":"13713.7","Tissue RNA - prostate [nTPM]":"2509.5","Tissue RNA - rectum [nTPM]":"97.7","Tissue RNA - retina [nTPM]":"4313.6","Tissue RNA - salivary gland [nTPM]":"4084.0","Tissue RNA - seminal vesicle [nTPM]":"40.6","Tissue RNA - skeletal muscle [nTPM]":"57879.2","Tissue RNA - skin 1 [nTPM]":"15225.1","Tissue RNA - small intestine [nTPM]":"8006.6","Tissue RNA - smooth muscle [nTPM]":"51.8","Tissue RNA - spinal cord [nTPM]":"1229.7","Tissue RNA - spleen [nTPM]":"4205.8","Tissue RNA - stomach 1 [nTPM]":"10030.4","Tissue RNA - testis [nTPM]":"1993.1","Tissue RNA - thalamus [nTPM]":"8318.4","Tissue RNA - thymus [nTPM]":"40.9","Tissue RNA - thyroid gland [nTPM]":"2562.5","Tissue RNA - tongue [nTPM]":"243.6","Tissue RNA - tonsil [nTPM]":"43.1","Tissue RNA - urinary bladder [nTPM]":"5236.3","Tissue RNA - vagina [nTPM]":"1897.2","Tissue RNA - white matter [nTPM]":"1060.7","Cell RNA - A-431 [nTPM]":"3305.7","Cell RNA - A549 [nTPM]":"2595.3","Cell RNA - AF22 [nTPM]":"2255.7","Cell RNA - AN3-CA [nTPM]":"2869.4","Cell RNA - ASC diff [nTPM]":"371.0","Cell RNA - ASC TERT1 [nTPM]":"34.6","Cell RNA - BEWO [nTPM]":"1614.6","Cell RNA - BJ [nTPM]":"4329.1","Cell RNA - BJ hTERT+ [nTPM]":"8.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.2","Cell RNA - CACO-2 [nTPM]":"3553.8","Cell RNA - CAPAN-2 [nTPM]":"3233.4","Cell RNA - Daudi [nTPM]":"6999.5","Cell RNA - EFO-21 [nTPM]":"2873.3","Cell RNA - fHDF\/TERT166 [nTPM]":"117.5","Cell RNA - GAMG [nTPM]":"423.7","Cell RNA - HaCaT [nTPM]":"4781.1","Cell RNA - HAP1 [nTPM]":"25.1","Cell RNA - HBEC3-KT [nTPM]":"79.1","Cell RNA - HBF TERT88 [nTPM]":"23.3","Cell RNA - HDLM-2 [nTPM]":"4178.5","Cell RNA - HEK 293 [nTPM]":"1966.3","Cell RNA - HEL [nTPM]":"4217.6","Cell RNA - HeLa [nTPM]":"20826.9","Cell RNA - Hep G2 [nTPM]":"10361.0","Cell RNA - HHSteC [nTPM]":"29.7","Cell RNA - HL-60 [nTPM]":"2704.1","Cell RNA - HMC-1 [nTPM]":"3805.1","Cell RNA - HSkMC [nTPM]":"64.4","Cell RNA - hTCEpi [nTPM]":"103.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"103.9","Cell RNA - hTERT-HME1 [nTPM]":"86.4","Cell RNA - hTERT-RPE1 [nTPM]":"2123.1","Cell RNA - HUVEC TERT2 [nTPM]":"23.2","Cell RNA - JURKAT [nTPM]":"1445.3","Cell RNA - K-562 [nTPM]":"1855.2","Cell RNA - Karpas-707 [nTPM]":"2671.0","Cell RNA - LHCN-M2 [nTPM]":"94.5","Cell RNA - MCF7 [nTPM]":"6976.5","Cell RNA - MOLT-4 [nTPM]":"836.0","Cell RNA - NB-4 [nTPM]":"3680.9","Cell RNA - NTERA-2 [nTPM]":"492.5","Cell RNA - OE19 [nTPM]":"1868.7","Cell RNA - PC-3 [nTPM]":"1267.3","Cell RNA - REH [nTPM]":"2002.7","Cell RNA - RH-30 [nTPM]":"1440.3","Cell RNA - RPMI-8226 [nTPM]":"3034.3","Cell RNA - RPTEC TERT1 [nTPM]":"60.9","Cell RNA - RT4 [nTPM]":"9493.6","Cell RNA - SCLC-21H [nTPM]":"926.2","Cell RNA - SH-SY5Y [nTPM]":"1476.3","Cell RNA - SiHa [nTPM]":"2250.2","Cell RNA - SK-BR-3 [nTPM]":"3898.6","Cell RNA - SK-MEL-30 [nTPM]":"1876.3","Cell RNA - SuSa [nTPM]":"3559.0","Cell RNA - T-47d [nTPM]":"3037.2","Cell RNA - THP-1 [nTPM]":"5182.3","Cell RNA - TIME [nTPM]":"8822.6","Cell RNA - U-138 MG [nTPM]":"2473.6","Cell RNA - U-2 OS [nTPM]":"2088.6","Cell RNA - U-2197 [nTPM]":"3550.5","Cell RNA - U-251 MG [nTPM]":"1766.8","Cell RNA - U-266\/70 [nTPM]":"906.6","Cell RNA - U-266\/84 [nTPM]":"2600.9","Cell RNA - U-698 [nTPM]":"1705.0","Cell RNA - U-87 MG [nTPM]":"1682.9","Cell RNA - U-937 [nTPM]":"2680.8","Cell RNA - WM-115 [nTPM]":"1473.8","Blood RNA - basophil [nTPM]":"2089.0","Blood RNA - classical monocyte [nTPM]":"1092.3","Blood RNA - eosinophil [nTPM]":"645.1","Blood RNA - gdT-cell [nTPM]":"733.4","Blood RNA - intermediate monocyte [nTPM]":"881.5","Blood RNA - MAIT T-cell [nTPM]":"840.2","Blood RNA - memory B-cell [nTPM]":"1047.3","Blood RNA - memory CD4 T-cell [nTPM]":"776.1","Blood RNA - memory CD8 T-cell [nTPM]":"800.0","Blood RNA - myeloid DC [nTPM]":"582.8","Blood RNA - naive B-cell [nTPM]":"1016.1","Blood RNA - naive CD4 T-cell [nTPM]":"760.2","Blood RNA - naive CD8 T-cell [nTPM]":"870.6","Blood RNA - neutrophil [nTPM]":"453.3","Blood RNA - NK-cell [nTPM]":"752.2","Blood RNA - non-classical monocyte [nTPM]":"963.0","Blood RNA - plasmacytoid DC [nTPM]":"790.6","Blood RNA - T-reg [nTPM]":"635.2","Blood RNA - total PBMC [nTPM]":"365.4","Brain RNA - amygdala [nTPM]":"5769.7","Brain RNA - basal ganglia [nTPM]":"3927.7","Brain RNA - cerebellum [nTPM]":"2199.5","Brain RNA - cerebral cortex [nTPM]":"5682.5","Brain RNA - hippocampal formation [nTPM]":"4361.1","Brain RNA - hypothalamus [nTPM]":"7820.0","Brain RNA - medulla oblongata [nTPM]":"13167.2","Brain RNA - midbrain [nTPM]":"11029.3","Brain RNA - pons [nTPM]":"13713.7","Brain RNA - spinal cord [nTPM]":"1229.7","Brain RNA - thalamus [nTPM]":"8318.4","Brain RNA - white matter [nTPM]":"1060.7","Single Cell Type RNA - Adipocytes [nTPM]":"31.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"83.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"62.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"328.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"55.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"75.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1210.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"52.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"31.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15756.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"273.1","Single Cell Type RNA - Club cells [nTPM]":"107.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"128.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"78.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"125.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"32.6","Single Cell Type RNA - Early spermatids [nTPM]":"8.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"154.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"132.5","Single Cell Type RNA - Endothelial cells [nTPM]":"478.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"30.1","Single Cell Type RNA - Erythroid cells [nTPM]":"797.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"35.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"396.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"886.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"247.7","Single Cell Type RNA - granulocytes [nTPM]":"98.0","Single Cell Type RNA - Granulosa cells [nTPM]":"130.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"385.8","Single Cell Type RNA - Hepatocytes [nTPM]":"699.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"59.8","Single Cell Type RNA - Ionocytes [nTPM]":"44.7","Single Cell Type RNA - Kupffer cells [nTPM]":"518.3","Single Cell Type RNA - Langerhans cells [nTPM]":"20.1","Single Cell Type RNA - Late spermatids [nTPM]":"33.4","Single Cell Type RNA - Leydig cells [nTPM]":"62.4","Single Cell Type RNA - Macrophages [nTPM]":"214.3","Single Cell Type RNA - Melanocytes [nTPM]":"33.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"66.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"48.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"25.6","Single Cell Type RNA - Paneth cells [nTPM]":"69.9","Single Cell Type RNA - Peritubular cells [nTPM]":"45.1","Single Cell Type RNA - Plasma cells [nTPM]":"1055.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"152.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"76.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"175.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"111.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"121.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"423.9","Single Cell Type RNA - Spermatocytes [nTPM]":"31.7","Single Cell Type RNA - Spermatogonia [nTPM]":"60.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1160.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"266.3","Single Cell Type RNA - Theca cells [nTPM]":"58.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"78.4","Single Cell Type RNA - Urothelial cells [nTPM]":"117.0"},{"Gene":"MTAP","Gene synonym":["c86fus","MSAP"],"Ensembl":"ENSG00000099810","Gene description":"Methylthioadenosine phosphorylase","Uniprot":["Q13126"],"Chromosome":"9","Position":"21802636-21937651","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Purine salvage"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046915","CAB080036","CAB080037"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3000000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB080036":"AB_11128130","CAB080037":"AB_11129069","HPA046915":"AB_2679862"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.68e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.9","Tissue RNA - adrenal gland [nTPM]":"6.5","Tissue RNA - amygdala [nTPM]":"4.1","Tissue RNA - appendix [nTPM]":"5.4","Tissue RNA - basal ganglia [nTPM]":"4.8","Tissue RNA - bone marrow [nTPM]":"5.8","Tissue RNA - breast [nTPM]":"8.5","Tissue RNA - cerebellum [nTPM]":"4.2","Tissue RNA - cerebral cortex [nTPM]":"5.7","Tissue RNA - cervix [nTPM]":"7.8","Tissue RNA - choroid plexus [nTPM]":"7.6","Tissue RNA - colon [nTPM]":"6.7","Tissue RNA - duodenum [nTPM]":"4.8","Tissue RNA - endometrium 1 [nTPM]":"8.8","Tissue RNA - epididymis [nTPM]":"7.1","Tissue RNA - esophagus [nTPM]":"8.8","Tissue RNA - fallopian tube [nTPM]":"7.1","Tissue RNA - gallbladder [nTPM]":"4.9","Tissue RNA - heart muscle [nTPM]":"7.0","Tissue RNA - hippocampal formation [nTPM]":"3.8","Tissue RNA - hypothalamus [nTPM]":"4.0","Tissue RNA - kidney [nTPM]":"6.9","Tissue RNA - liver [nTPM]":"10.9","Tissue RNA - lung [nTPM]":"5.8","Tissue RNA - lymph node [nTPM]":"6.3","Tissue RNA - medulla oblongata [nTPM]":"5.0","Tissue RNA - midbrain [nTPM]":"4.5","Tissue RNA - ovary [nTPM]":"12.1","Tissue RNA - pancreas [nTPM]":"6.6","Tissue RNA - parathyroid gland [nTPM]":"8.4","Tissue RNA - pituitary gland [nTPM]":"2.8","Tissue RNA - placenta [nTPM]":"8.9","Tissue RNA - pons [nTPM]":"5.1","Tissue RNA - prostate [nTPM]":"7.2","Tissue RNA - rectum [nTPM]":"8.0","Tissue RNA - retina [nTPM]":"3.9","Tissue RNA - salivary gland [nTPM]":"6.5","Tissue RNA - seminal vesicle [nTPM]":"7.0","Tissue RNA - skeletal muscle [nTPM]":"4.5","Tissue RNA - skin 1 [nTPM]":"7.0","Tissue RNA - small intestine [nTPM]":"5.9","Tissue RNA - smooth muscle [nTPM]":"9.0","Tissue RNA - spinal cord [nTPM]":"4.0","Tissue RNA - spleen [nTPM]":"7.3","Tissue RNA - stomach 1 [nTPM]":"7.2","Tissue RNA - testis [nTPM]":"2.9","Tissue RNA - thalamus [nTPM]":"5.4","Tissue RNA - thymus [nTPM]":"6.8","Tissue RNA - thyroid gland [nTPM]":"7.2","Tissue RNA - tongue [nTPM]":"5.4","Tissue RNA - tonsil [nTPM]":"7.3","Tissue RNA - urinary bladder [nTPM]":"10.1","Tissue RNA - vagina [nTPM]":"7.4","Tissue RNA - white matter [nTPM]":"6.0","Cell RNA - A-431 [nTPM]":"30.4","Cell RNA - A549 [nTPM]":"1.0","Cell RNA - AF22 [nTPM]":"23.0","Cell RNA - AN3-CA [nTPM]":"19.0","Cell RNA - ASC diff [nTPM]":"19.4","Cell RNA - ASC TERT1 [nTPM]":"19.0","Cell RNA - BEWO [nTPM]":"28.3","Cell RNA - BJ [nTPM]":"42.3","Cell RNA - BJ hTERT+ [nTPM]":"21.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.3","Cell RNA - CACO-2 [nTPM]":"21.7","Cell RNA - CAPAN-2 [nTPM]":"14.6","Cell RNA - Daudi [nTPM]":"15.3","Cell RNA - EFO-21 [nTPM]":"13.4","Cell RNA - fHDF\/TERT166 [nTPM]":"21.1","Cell RNA - GAMG [nTPM]":"16.3","Cell RNA - HaCaT [nTPM]":"15.2","Cell RNA - HAP1 [nTPM]":"24.4","Cell RNA - HBEC3-KT [nTPM]":"59.5","Cell RNA - HBF TERT88 [nTPM]":"36.8","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"19.8","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"56.8","Cell RNA - Hep G2 [nTPM]":"28.8","Cell RNA - HHSteC [nTPM]":"18.6","Cell RNA - HL-60 [nTPM]":"24.5","Cell RNA - HMC-1 [nTPM]":"26.3","Cell RNA - HSkMC [nTPM]":"23.5","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"38.6","Cell RNA - hTERT-HME1 [nTPM]":"42.6","Cell RNA - hTERT-RPE1 [nTPM]":"24.4","Cell RNA - HUVEC TERT2 [nTPM]":"22.6","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"20.1","Cell RNA - LHCN-M2 [nTPM]":"21.9","Cell RNA - MCF7 [nTPM]":"3.1","Cell RNA - MOLT-4 [nTPM]":"26.8","Cell RNA - NB-4 [nTPM]":"0.7","Cell RNA - NTERA-2 [nTPM]":"27.5","Cell RNA - OE19 [nTPM]":"14.7","Cell RNA - PC-3 [nTPM]":"35.2","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"18.0","Cell RNA - RPMI-8226 [nTPM]":"26.0","Cell RNA - RPTEC TERT1 [nTPM]":"18.3","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"14.4","Cell RNA - SH-SY5Y [nTPM]":"15.3","Cell RNA - SiHa [nTPM]":"14.4","Cell RNA - SK-BR-3 [nTPM]":"17.1","Cell RNA - SK-MEL-30 [nTPM]":"21.1","Cell RNA - SuSa [nTPM]":"17.9","Cell RNA - T-47d [nTPM]":"10.9","Cell RNA - THP-1 [nTPM]":"0.6","Cell RNA - TIME [nTPM]":"23.8","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"15.7","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"34.4","Cell RNA - U-266\/70 [nTPM]":"13.7","Cell RNA - U-266\/84 [nTPM]":"25.5","Cell RNA - U-698 [nTPM]":"30.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"24.3","Cell RNA - WM-115 [nTPM]":"12.0","Blood RNA - basophil [nTPM]":"1.2","Blood RNA - classical monocyte [nTPM]":"5.6","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"3.6","Blood RNA - intermediate monocyte [nTPM]":"4.5","Blood RNA - MAIT T-cell [nTPM]":"6.1","Blood RNA - memory B-cell [nTPM]":"5.9","Blood RNA - memory CD4 T-cell [nTPM]":"5.3","Blood RNA - memory CD8 T-cell [nTPM]":"4.2","Blood RNA - myeloid DC [nTPM]":"6.9","Blood RNA - naive B-cell [nTPM]":"8.4","Blood RNA - naive CD4 T-cell [nTPM]":"4.6","Blood RNA - naive CD8 T-cell [nTPM]":"4.2","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"6.7","Blood RNA - non-classical monocyte [nTPM]":"2.9","Blood RNA - plasmacytoid DC [nTPM]":"6.3","Blood RNA - T-reg [nTPM]":"3.2","Blood RNA - total PBMC [nTPM]":"2.7","Brain RNA - amygdala [nTPM]":"4.1","Brain RNA - basal ganglia [nTPM]":"4.8","Brain RNA - cerebellum [nTPM]":"4.2","Brain RNA - cerebral cortex [nTPM]":"5.7","Brain RNA - hippocampal formation [nTPM]":"3.8","Brain RNA - hypothalamus [nTPM]":"4.0","Brain RNA - medulla oblongata [nTPM]":"5.0","Brain RNA - midbrain [nTPM]":"4.5","Brain RNA - pons [nTPM]":"5.1","Brain RNA - spinal cord [nTPM]":"4.0","Brain RNA - thalamus [nTPM]":"5.4","Brain RNA - white matter [nTPM]":"6.0","Single Cell Type RNA - Adipocytes [nTPM]":"18.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.8","Single Cell Type RNA - Astrocytes [nTPM]":"26.1","Single Cell Type RNA - B-cells [nTPM]":"16.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"58.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"16.5","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"20.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"22.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"27.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"52.3","Single Cell Type RNA - dendritic cells [nTPM]":"11.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"38.6","Single Cell Type RNA - Early spermatids [nTPM]":"77.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"28.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"28.5","Single Cell Type RNA - Endothelial cells [nTPM]":"14.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"19.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"28.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"80.0","Single Cell Type RNA - Fibroblasts [nTPM]":"18.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"40.6","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"30.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.5","Single Cell Type RNA - Hepatocytes [nTPM]":"22.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"27.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.3","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"25.5","Single Cell Type RNA - Langerhans cells [nTPM]":"11.1","Single Cell Type RNA - Late spermatids [nTPM]":"14.8","Single Cell Type RNA - Leydig cells [nTPM]":"14.9","Single Cell Type RNA - Macrophages [nTPM]":"15.1","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"48.7","Single Cell Type RNA - monocytes [nTPM]":"15.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"40.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"32.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"41.5","Single Cell Type RNA - Paneth cells [nTPM]":"6.8","Single Cell Type RNA - Peritubular cells [nTPM]":"14.7","Single Cell Type RNA - Plasma cells [nTPM]":"13.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"45.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.3","Single Cell Type RNA - Spermatogonia [nTPM]":"13.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"35.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.6","Single Cell Type RNA - T-cells [nTPM]":"15.1","Single Cell Type RNA - Theca cells [nTPM]":"33.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.7","Single Cell Type RNA - Urothelial cells [nTPM]":"62.9"},{"Gene":"MTFMT","Gene synonym":["FMT1"],"Ensembl":"ENSG00000103707","Gene description":"Mitochondrial methionyl-tRNA formyltransferase","Uniprot":["Q96DP5"],"Chromosome":"15","Position":"65001512-65029639","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"49.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040710"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA040710":"AB_10794879"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.31e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.6","Tissue RNA - adrenal gland [nTPM]":"2.2","Tissue RNA - amygdala [nTPM]":"2.6","Tissue RNA - appendix [nTPM]":"0.7","Tissue RNA - basal ganglia [nTPM]":"2.9","Tissue RNA - bone marrow [nTPM]":"1.9","Tissue RNA - breast [nTPM]":"1.6","Tissue RNA - cerebellum [nTPM]":"3.8","Tissue RNA - cerebral cortex [nTPM]":"3.1","Tissue RNA - cervix [nTPM]":"2.4","Tissue RNA - choroid plexus [nTPM]":"4.0","Tissue RNA - colon [nTPM]":"2.5","Tissue RNA - duodenum [nTPM]":"1.5","Tissue RNA - endometrium 1 [nTPM]":"2.5","Tissue RNA - epididymis [nTPM]":"1.5","Tissue RNA - esophagus [nTPM]":"2.2","Tissue RNA - fallopian tube [nTPM]":"2.6","Tissue RNA - gallbladder [nTPM]":"0.9","Tissue RNA - heart muscle [nTPM]":"4.3","Tissue RNA - hippocampal formation [nTPM]":"2.5","Tissue RNA - hypothalamus [nTPM]":"3.4","Tissue RNA - kidney [nTPM]":"2.4","Tissue RNA - liver [nTPM]":"3.5","Tissue RNA - lung [nTPM]":"1.5","Tissue RNA - lymph node [nTPM]":"1.3","Tissue RNA - medulla oblongata [nTPM]":"2.5","Tissue RNA - midbrain [nTPM]":"2.2","Tissue RNA - ovary [nTPM]":"2.7","Tissue RNA - pancreas [nTPM]":"1.4","Tissue RNA - parathyroid gland [nTPM]":"1.7","Tissue RNA - pituitary gland [nTPM]":"2.2","Tissue RNA - placenta [nTPM]":"0.8","Tissue RNA - pons [nTPM]":"2.5","Tissue RNA - prostate [nTPM]":"2.8","Tissue RNA - rectum [nTPM]":"1.5","Tissue RNA - retina [nTPM]":"1.6","Tissue RNA - salivary gland [nTPM]":"1.8","Tissue RNA - seminal vesicle [nTPM]":"1.3","Tissue RNA - skeletal muscle [nTPM]":"3.0","Tissue RNA - skin 1 [nTPM]":"1.7","Tissue RNA - small intestine [nTPM]":"2.2","Tissue RNA - smooth muscle [nTPM]":"1.7","Tissue RNA - spinal cord [nTPM]":"1.9","Tissue RNA - spleen [nTPM]":"2.3","Tissue RNA - stomach 1 [nTPM]":"2.0","Tissue RNA - testis [nTPM]":"1.5","Tissue RNA - thalamus [nTPM]":"2.9","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"1.7","Tissue RNA - tongue [nTPM]":"1.5","Tissue RNA - tonsil [nTPM]":"1.2","Tissue RNA - urinary bladder [nTPM]":"2.5","Tissue RNA - vagina [nTPM]":"2.1","Tissue RNA - white matter [nTPM]":"2.6","Cell RNA - A-431 [nTPM]":"1.4","Cell RNA - A549 [nTPM]":"1.9","Cell RNA - AF22 [nTPM]":"1.8","Cell RNA - AN3-CA [nTPM]":"3.2","Cell RNA - ASC diff [nTPM]":"2.5","Cell RNA - ASC TERT1 [nTPM]":"1.7","Cell RNA - BEWO [nTPM]":"1.7","Cell RNA - BJ [nTPM]":"1.3","Cell RNA - BJ hTERT+ [nTPM]":"2.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.5","Cell RNA - CACO-2 [nTPM]":"1.2","Cell RNA - CAPAN-2 [nTPM]":"1.5","Cell RNA - Daudi [nTPM]":"4.7","Cell RNA - EFO-21 [nTPM]":"1.7","Cell RNA - fHDF\/TERT166 [nTPM]":"2.3","Cell RNA - GAMG [nTPM]":"2.7","Cell RNA - HaCaT [nTPM]":"4.0","Cell RNA - HAP1 [nTPM]":"3.3","Cell RNA - HBEC3-KT [nTPM]":"2.2","Cell RNA - HBF TERT88 [nTPM]":"1.5","Cell RNA - HDLM-2 [nTPM]":"1.9","Cell RNA - HEK 293 [nTPM]":"2.8","Cell RNA - HEL [nTPM]":"1.9","Cell RNA - HeLa [nTPM]":"1.9","Cell RNA - Hep G2 [nTPM]":"1.3","Cell RNA - HHSteC [nTPM]":"2.9","Cell RNA - HL-60 [nTPM]":"2.7","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"2.3","Cell RNA - hTCEpi [nTPM]":"2.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.9","Cell RNA - hTERT-HME1 [nTPM]":"1.9","Cell RNA - hTERT-RPE1 [nTPM]":"2.2","Cell RNA - HUVEC TERT2 [nTPM]":"1.5","Cell RNA - JURKAT [nTPM]":"4.2","Cell RNA - K-562 [nTPM]":"2.3","Cell RNA - Karpas-707 [nTPM]":"2.2","Cell RNA - LHCN-M2 [nTPM]":"2.4","Cell RNA - MCF7 [nTPM]":"1.9","Cell RNA - MOLT-4 [nTPM]":"2.3","Cell RNA - NB-4 [nTPM]":"3.1","Cell RNA - NTERA-2 [nTPM]":"2.4","Cell RNA - OE19 [nTPM]":"4.0","Cell RNA - PC-3 [nTPM]":"3.6","Cell RNA - REH [nTPM]":"2.0","Cell RNA - RH-30 [nTPM]":"2.5","Cell RNA - RPMI-8226 [nTPM]":"2.2","Cell RNA - RPTEC TERT1 [nTPM]":"2.7","Cell RNA - RT4 [nTPM]":"1.6","Cell RNA - SCLC-21H [nTPM]":"1.8","Cell RNA - SH-SY5Y [nTPM]":"1.8","Cell RNA - SiHa [nTPM]":"3.1","Cell RNA - SK-BR-3 [nTPM]":"2.7","Cell RNA - SK-MEL-30 [nTPM]":"2.5","Cell RNA - SuSa [nTPM]":"2.2","Cell RNA - T-47d [nTPM]":"1.6","Cell RNA - THP-1 [nTPM]":"2.0","Cell RNA - TIME [nTPM]":"2.8","Cell RNA - U-138 MG [nTPM]":"1.9","Cell RNA - U-2 OS [nTPM]":"1.9","Cell RNA - U-2197 [nTPM]":"2.4","Cell RNA - U-251 MG [nTPM]":"2.6","Cell RNA - U-266\/70 [nTPM]":"1.9","Cell RNA - U-266\/84 [nTPM]":"3.1","Cell RNA - U-698 [nTPM]":"1.8","Cell RNA - U-87 MG [nTPM]":"1.7","Cell RNA - U-937 [nTPM]":"4.6","Cell RNA - WM-115 [nTPM]":"1.9","Blood RNA - basophil [nTPM]":"3.7","Blood RNA - classical monocyte [nTPM]":"3.3","Blood RNA - eosinophil [nTPM]":"2.6","Blood RNA - gdT-cell [nTPM]":"4.8","Blood RNA - intermediate monocyte [nTPM]":"3.1","Blood RNA - MAIT T-cell [nTPM]":"4.8","Blood RNA - memory B-cell [nTPM]":"4.8","Blood RNA - memory CD4 T-cell [nTPM]":"4.7","Blood RNA - memory CD8 T-cell [nTPM]":"5.0","Blood RNA - myeloid DC [nTPM]":"6.0","Blood RNA - naive B-cell [nTPM]":"4.7","Blood RNA - naive CD4 T-cell [nTPM]":"5.1","Blood RNA - naive CD8 T-cell [nTPM]":"5.4","Blood RNA - neutrophil [nTPM]":"16.5","Blood RNA - NK-cell [nTPM]":"4.5","Blood RNA - non-classical monocyte [nTPM]":"2.2","Blood RNA - plasmacytoid DC [nTPM]":"10.1","Blood RNA - T-reg [nTPM]":"5.4","Blood RNA - total PBMC [nTPM]":"2.3","Brain RNA - amygdala [nTPM]":"2.6","Brain RNA - basal ganglia [nTPM]":"2.9","Brain RNA - cerebellum [nTPM]":"3.8","Brain RNA - cerebral cortex [nTPM]":"3.1","Brain RNA - hippocampal formation [nTPM]":"2.5","Brain RNA - hypothalamus [nTPM]":"3.4","Brain RNA - medulla oblongata [nTPM]":"2.5","Brain RNA - midbrain [nTPM]":"2.2","Brain RNA - pons [nTPM]":"2.5","Brain RNA - spinal cord [nTPM]":"1.9","Brain RNA - thalamus [nTPM]":"2.9","Brain RNA - white matter [nTPM]":"2.6","Single Cell Type RNA - Adipocytes [nTPM]":"8.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.7","Single Cell Type RNA - Astrocytes [nTPM]":"17.0","Single Cell Type RNA - B-cells [nTPM]":"11.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"19.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"10.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.4","Single Cell Type RNA - dendritic cells [nTPM]":"18.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"25.4","Single Cell Type RNA - Ductal cells [nTPM]":"11.8","Single Cell Type RNA - Early spermatids [nTPM]":"1.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.6","Single Cell Type RNA - Endothelial cells [nTPM]":"8.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.8","Single Cell Type RNA - Erythroid cells [nTPM]":"9.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"49.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.7","Single Cell Type RNA - Fibroblasts [nTPM]":"11.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.0","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"8.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.8","Single Cell Type RNA - Hepatocytes [nTPM]":"12.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"44.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.9","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"12.2","Single Cell Type RNA - Langerhans cells [nTPM]":"12.2","Single Cell Type RNA - Late spermatids [nTPM]":"1.7","Single Cell Type RNA - Leydig cells [nTPM]":"15.5","Single Cell Type RNA - Macrophages [nTPM]":"9.7","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"27.2","Single Cell Type RNA - monocytes [nTPM]":"7.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.3","Single Cell Type RNA - Paneth cells [nTPM]":"15.9","Single Cell Type RNA - Peritubular cells [nTPM]":"15.4","Single Cell Type RNA - Plasma cells [nTPM]":"10.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"25.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.5","Single Cell Type RNA - Spermatocytes [nTPM]":"13.3","Single Cell Type RNA - Spermatogonia [nTPM]":"20.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.9","Single Cell Type RNA - T-cells [nTPM]":"10.1","Single Cell Type RNA - Theca cells [nTPM]":"11.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.7","Single Cell Type RNA - Urothelial cells [nTPM]":"14.5"},{"Gene":"MTHFR","Gene synonym":[],"Ensembl":"ENSG00000177000","Gene description":"Methylenetetrahydrofolate reductase","Uniprot":["P42898"],"Chromosome":"1","Position":"11785723-11806455","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Allosteric enzyme","Oxidoreductase"],"Disease involvement":["Disease variant","Schizophrenia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"K-562":"44.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063389","HPA076180","HPA077255"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA063389":"AB_2685001","HPA076180":null,"HPA077255":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.97e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.19e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.81e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.12e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Tissue RNA - adipose tissue [nTPM]":"12.3","Tissue RNA - adrenal gland [nTPM]":"11.3","Tissue RNA - amygdala [nTPM]":"7.1","Tissue RNA - appendix [nTPM]":"10.8","Tissue RNA - basal ganglia [nTPM]":"10.3","Tissue RNA - bone marrow [nTPM]":"28.9","Tissue RNA - breast [nTPM]":"10.2","Tissue RNA - cerebellum [nTPM]":"12.8","Tissue RNA - cerebral cortex [nTPM]":"8.8","Tissue RNA - cervix [nTPM]":"9.0","Tissue RNA - choroid plexus [nTPM]":"5.0","Tissue RNA - colon [nTPM]":"11.1","Tissue RNA - duodenum [nTPM]":"10.8","Tissue RNA - endometrium 1 [nTPM]":"8.9","Tissue RNA - epididymis [nTPM]":"53.5","Tissue RNA - esophagus [nTPM]":"10.3","Tissue RNA - fallopian tube [nTPM]":"12.3","Tissue RNA - gallbladder [nTPM]":"10.1","Tissue RNA - heart muscle [nTPM]":"23.9","Tissue RNA - hippocampal formation [nTPM]":"10.4","Tissue RNA - hypothalamus [nTPM]":"6.2","Tissue RNA - kidney [nTPM]":"12.8","Tissue RNA - liver [nTPM]":"13.1","Tissue RNA - lung [nTPM]":"16.8","Tissue RNA - lymph node [nTPM]":"12.3","Tissue RNA - medulla oblongata [nTPM]":"9.9","Tissue RNA - midbrain [nTPM]":"7.0","Tissue RNA - ovary [nTPM]":"19.7","Tissue RNA - pancreas [nTPM]":"11.4","Tissue RNA - parathyroid gland [nTPM]":"6.6","Tissue RNA - pituitary gland [nTPM]":"17.7","Tissue RNA - placenta [nTPM]":"7.1","Tissue RNA - pons [nTPM]":"9.4","Tissue RNA - prostate [nTPM]":"10.2","Tissue RNA - rectum [nTPM]":"8.7","Tissue RNA - retina [nTPM]":"12.6","Tissue RNA - salivary gland [nTPM]":"6.8","Tissue RNA - seminal vesicle [nTPM]":"6.7","Tissue RNA - skeletal muscle [nTPM]":"17.9","Tissue RNA - skin 1 [nTPM]":"13.4","Tissue RNA - small intestine [nTPM]":"14.7","Tissue RNA - smooth muscle [nTPM]":"10.8","Tissue RNA - spinal cord [nTPM]":"5.1","Tissue RNA - spleen [nTPM]":"18.3","Tissue RNA - stomach 1 [nTPM]":"14.6","Tissue RNA - testis [nTPM]":"10.9","Tissue RNA - thalamus [nTPM]":"8.0","Tissue RNA - thymus [nTPM]":"7.9","Tissue RNA - thyroid gland [nTPM]":"16.3","Tissue RNA - tongue [nTPM]":"16.8","Tissue RNA - tonsil [nTPM]":"12.2","Tissue RNA - urinary bladder [nTPM]":"10.3","Tissue RNA - vagina [nTPM]":"7.9","Tissue RNA - white matter [nTPM]":"8.9","Cell RNA - A-431 [nTPM]":"2.2","Cell RNA - A549 [nTPM]":"9.4","Cell RNA - AF22 [nTPM]":"10.9","Cell RNA - AN3-CA [nTPM]":"12.3","Cell RNA - ASC diff [nTPM]":"10.2","Cell RNA - ASC TERT1 [nTPM]":"15.1","Cell RNA - BEWO [nTPM]":"2.0","Cell RNA - BJ [nTPM]":"5.2","Cell RNA - BJ hTERT+ [nTPM]":"14.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.1","Cell RNA - CACO-2 [nTPM]":"8.1","Cell RNA - CAPAN-2 [nTPM]":"13.2","Cell RNA - Daudi [nTPM]":"18.0","Cell RNA - EFO-21 [nTPM]":"3.6","Cell RNA - fHDF\/TERT166 [nTPM]":"7.5","Cell RNA - GAMG [nTPM]":"16.3","Cell RNA - HaCaT [nTPM]":"4.1","Cell RNA - HAP1 [nTPM]":"8.1","Cell RNA - HBEC3-KT [nTPM]":"7.7","Cell RNA - HBF TERT88 [nTPM]":"2.4","Cell RNA - HDLM-2 [nTPM]":"9.3","Cell RNA - HEK 293 [nTPM]":"6.8","Cell RNA - HEL [nTPM]":"13.4","Cell RNA - HeLa [nTPM]":"13.3","Cell RNA - Hep G2 [nTPM]":"3.2","Cell RNA - HHSteC [nTPM]":"13.7","Cell RNA - HL-60 [nTPM]":"7.4","Cell RNA - HMC-1 [nTPM]":"16.4","Cell RNA - HSkMC [nTPM]":"13.6","Cell RNA - hTCEpi [nTPM]":"6.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.0","Cell RNA - hTERT-HME1 [nTPM]":"6.4","Cell RNA - hTERT-RPE1 [nTPM]":"10.0","Cell RNA - HUVEC TERT2 [nTPM]":"10.7","Cell RNA - JURKAT [nTPM]":"17.2","Cell RNA - K-562 [nTPM]":"44.1","Cell RNA - Karpas-707 [nTPM]":"11.0","Cell RNA - LHCN-M2 [nTPM]":"6.7","Cell RNA - MCF7 [nTPM]":"3.3","Cell RNA - MOLT-4 [nTPM]":"8.2","Cell RNA - NB-4 [nTPM]":"3.5","Cell RNA - NTERA-2 [nTPM]":"3.6","Cell RNA - OE19 [nTPM]":"9.5","Cell RNA - PC-3 [nTPM]":"3.0","Cell RNA - REH [nTPM]":"8.9","Cell RNA - RH-30 [nTPM]":"6.0","Cell RNA - RPMI-8226 [nTPM]":"20.3","Cell RNA - RPTEC TERT1 [nTPM]":"8.8","Cell RNA - RT4 [nTPM]":"11.7","Cell RNA - SCLC-21H [nTPM]":"10.5","Cell RNA - SH-SY5Y [nTPM]":"17.6","Cell RNA - SiHa [nTPM]":"8.1","Cell RNA - SK-BR-3 [nTPM]":"7.8","Cell RNA - SK-MEL-30 [nTPM]":"10.9","Cell RNA - SuSa [nTPM]":"6.2","Cell RNA - T-47d [nTPM]":"12.9","Cell RNA - THP-1 [nTPM]":"11.7","Cell RNA - TIME [nTPM]":"8.5","Cell RNA - U-138 MG [nTPM]":"6.0","Cell RNA - U-2 OS [nTPM]":"4.9","Cell RNA - U-2197 [nTPM]":"7.2","Cell RNA - U-251 MG [nTPM]":"1.6","Cell RNA - U-266\/70 [nTPM]":"6.4","Cell RNA - U-266\/84 [nTPM]":"9.4","Cell RNA - U-698 [nTPM]":"32.8","Cell RNA - U-87 MG [nTPM]":"7.6","Cell RNA - U-937 [nTPM]":"16.8","Cell RNA - WM-115 [nTPM]":"5.6","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"2.3","Blood RNA - eosinophil [nTPM]":"1.1","Blood RNA - gdT-cell [nTPM]":"2.7","Blood RNA - intermediate monocyte [nTPM]":"4.3","Blood RNA - MAIT T-cell [nTPM]":"0.9","Blood RNA - memory B-cell [nTPM]":"1.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"1.7","Blood RNA - naive B-cell [nTPM]":"2.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"1.4","Blood RNA - neutrophil [nTPM]":"2.5","Blood RNA - NK-cell [nTPM]":"2.0","Blood RNA - non-classical monocyte [nTPM]":"6.1","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"1.6","Brain RNA - amygdala [nTPM]":"7.1","Brain RNA - basal ganglia [nTPM]":"10.3","Brain RNA - cerebellum [nTPM]":"12.8","Brain RNA - cerebral cortex [nTPM]":"8.8","Brain RNA - hippocampal formation [nTPM]":"10.4","Brain RNA - hypothalamus [nTPM]":"6.2","Brain RNA - medulla oblongata [nTPM]":"9.9","Brain RNA - midbrain [nTPM]":"7.0","Brain RNA - pons [nTPM]":"9.4","Brain RNA - spinal cord [nTPM]":"5.1","Brain RNA - thalamus [nTPM]":"8.0","Brain RNA - white matter [nTPM]":"8.9","Single Cell Type RNA - Adipocytes [nTPM]":"15.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"48.0","Single Cell Type RNA - Astrocytes [nTPM]":"8.1","Single Cell Type RNA - B-cells [nTPM]":"18.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"37.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"13.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.1","Single Cell Type RNA - dendritic cells [nTPM]":"6.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.9","Single Cell Type RNA - Early spermatids [nTPM]":"18.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"32.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"25.8","Single Cell Type RNA - Endothelial cells [nTPM]":"16.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.1","Single Cell Type RNA - Erythroid cells [nTPM]":"29.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.3","Single Cell Type RNA - Fibroblasts [nTPM]":"21.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"52.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"55.5","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"10.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"37.5","Single Cell Type RNA - Hepatocytes [nTPM]":"23.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"39.3","Single Cell Type RNA - Langerhans cells [nTPM]":"39.9","Single Cell Type RNA - Late spermatids [nTPM]":"42.4","Single Cell Type RNA - Leydig cells [nTPM]":"18.3","Single Cell Type RNA - Macrophages [nTPM]":"32.1","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"26.5","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"13.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.9","Single Cell Type RNA - Paneth cells [nTPM]":"20.6","Single Cell Type RNA - Peritubular cells [nTPM]":"9.1","Single Cell Type RNA - Plasma cells [nTPM]":"10.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"36.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.3","Single Cell Type RNA - Spermatocytes [nTPM]":"6.8","Single Cell Type RNA - Spermatogonia [nTPM]":"5.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.9","Single Cell Type RNA - T-cells [nTPM]":"10.6","Single Cell Type RNA - Theca cells [nTPM]":"21.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.6","Single Cell Type RNA - Urothelial cells [nTPM]":"9.6"},{"Gene":"MTHFS","Gene synonym":["HsT19268"],"Ensembl":"ENSG00000136371","Gene description":"Methenyltetrahydrofolate synthetase","Uniprot":["P49914"],"Chromosome":"15","Position":"79833585-79897379","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Ligase"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"liver":"253.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"205.5","monocytes":"150.8","Proximal tubular cells":"201.6","Syncytiotrophoblasts":"253.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"134.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"134.1","monocytes":"49.1"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008067","HPA054177"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"13000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA008067":"AB_1078882","HPA054177":"AB_2682405"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.52e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.29e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.04e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Tissue RNA - adipose tissue [nTPM]":"21.9","Tissue RNA - adrenal gland [nTPM]":"19.8","Tissue RNA - amygdala [nTPM]":"8.0","Tissue RNA - appendix [nTPM]":"4.6","Tissue RNA - basal ganglia [nTPM]":"8.2","Tissue RNA - bone marrow [nTPM]":"5.0","Tissue RNA - breast [nTPM]":"19.0","Tissue RNA - cerebellum [nTPM]":"9.6","Tissue RNA - cerebral cortex [nTPM]":"12.7","Tissue RNA - cervix [nTPM]":"9.9","Tissue RNA - choroid plexus [nTPM]":"6.9","Tissue RNA - colon [nTPM]":"12.0","Tissue RNA - duodenum [nTPM]":"13.7","Tissue RNA - endometrium 1 [nTPM]":"9.0","Tissue RNA - epididymis [nTPM]":"10.3","Tissue RNA - esophagus [nTPM]":"10.1","Tissue RNA - fallopian tube [nTPM]":"9.4","Tissue RNA - gallbladder [nTPM]":"7.0","Tissue RNA - heart muscle [nTPM]":"19.0","Tissue RNA - hippocampal formation [nTPM]":"8.0","Tissue RNA - hypothalamus [nTPM]":"9.2","Tissue RNA - kidney [nTPM]":"53.1","Tissue RNA - liver [nTPM]":"253.4","Tissue RNA - lung [nTPM]":"17.8","Tissue RNA - lymph node [nTPM]":"6.4","Tissue RNA - medulla oblongata [nTPM]":"8.7","Tissue RNA - midbrain [nTPM]":"9.3","Tissue RNA - ovary [nTPM]":"8.6","Tissue RNA - pancreas [nTPM]":"32.8","Tissue RNA - parathyroid gland [nTPM]":"26.3","Tissue RNA - pituitary gland [nTPM]":"21.5","Tissue RNA - placenta [nTPM]":"8.3","Tissue RNA - pons [nTPM]":"9.1","Tissue RNA - prostate [nTPM]":"19.5","Tissue RNA - rectum [nTPM]":"6.4","Tissue RNA - retina [nTPM]":"5.9","Tissue RNA - salivary gland [nTPM]":"13.6","Tissue RNA - seminal vesicle [nTPM]":"5.5","Tissue RNA - skeletal muscle [nTPM]":"20.2","Tissue RNA - skin 1 [nTPM]":"6.2","Tissue RNA - small intestine [nTPM]":"14.5","Tissue RNA - smooth muscle [nTPM]":"6.2","Tissue RNA - spinal cord [nTPM]":"8.8","Tissue RNA - spleen [nTPM]":"14.9","Tissue RNA - stomach 1 [nTPM]":"19.5","Tissue RNA - testis [nTPM]":"12.1","Tissue RNA - thalamus [nTPM]":"8.7","Tissue RNA - thymus [nTPM]":"10.6","Tissue RNA - thyroid gland [nTPM]":"15.9","Tissue RNA - tongue [nTPM]":"11.1","Tissue RNA - tonsil [nTPM]":"10.8","Tissue RNA - urinary bladder [nTPM]":"12.4","Tissue RNA - vagina [nTPM]":"9.9","Tissue RNA - white matter [nTPM]":"9.1","Cell RNA - A-431 [nTPM]":"12.6","Cell RNA - A549 [nTPM]":"35.8","Cell RNA - AF22 [nTPM]":"5.0","Cell RNA - AN3-CA [nTPM]":"2.6","Cell RNA - ASC diff [nTPM]":"15.8","Cell RNA - ASC TERT1 [nTPM]":"12.0","Cell RNA - BEWO [nTPM]":"11.9","Cell RNA - BJ [nTPM]":"8.8","Cell RNA - BJ hTERT+ [nTPM]":"13.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.5","Cell RNA - CACO-2 [nTPM]":"34.5","Cell RNA - CAPAN-2 [nTPM]":"22.4","Cell RNA - Daudi [nTPM]":"15.1","Cell RNA - EFO-21 [nTPM]":"25.1","Cell RNA - fHDF\/TERT166 [nTPM]":"15.5","Cell RNA - GAMG [nTPM]":"15.0","Cell RNA - HaCaT [nTPM]":"19.5","Cell RNA - HAP1 [nTPM]":"31.9","Cell RNA - HBEC3-KT [nTPM]":"10.7","Cell RNA - HBF TERT88 [nTPM]":"15.4","Cell RNA - HDLM-2 [nTPM]":"14.7","Cell RNA - HEK 293 [nTPM]":"28.4","Cell RNA - HEL [nTPM]":"14.8","Cell RNA - HeLa [nTPM]":"22.9","Cell RNA - Hep G2 [nTPM]":"39.8","Cell RNA - HHSteC [nTPM]":"25.3","Cell RNA - HL-60 [nTPM]":"7.8","Cell RNA - HMC-1 [nTPM]":"0.8","Cell RNA - HSkMC [nTPM]":"17.5","Cell RNA - hTCEpi [nTPM]":"27.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.1","Cell RNA - hTERT-HME1 [nTPM]":"23.0","Cell RNA - hTERT-RPE1 [nTPM]":"19.6","Cell RNA - HUVEC TERT2 [nTPM]":"7.4","Cell RNA - JURKAT [nTPM]":"16.0","Cell RNA - K-562 [nTPM]":"28.8","Cell RNA - Karpas-707 [nTPM]":"12.0","Cell RNA - LHCN-M2 [nTPM]":"17.4","Cell RNA - MCF7 [nTPM]":"36.0","Cell RNA - MOLT-4 [nTPM]":"10.2","Cell RNA - NB-4 [nTPM]":"36.1","Cell RNA - NTERA-2 [nTPM]":"15.6","Cell RNA - OE19 [nTPM]":"51.4","Cell RNA - PC-3 [nTPM]":"17.0","Cell RNA - REH [nTPM]":"10.8","Cell RNA - RH-30 [nTPM]":"17.2","Cell RNA - RPMI-8226 [nTPM]":"25.8","Cell RNA - RPTEC TERT1 [nTPM]":"35.1","Cell RNA - RT4 [nTPM]":"34.3","Cell RNA - SCLC-21H [nTPM]":"8.9","Cell RNA - SH-SY5Y [nTPM]":"4.8","Cell RNA - SiHa [nTPM]":"25.1","Cell RNA - SK-BR-3 [nTPM]":"14.2","Cell RNA - SK-MEL-30 [nTPM]":"43.8","Cell RNA - SuSa [nTPM]":"20.0","Cell RNA - T-47d [nTPM]":"17.3","Cell RNA - THP-1 [nTPM]":"13.0","Cell RNA - TIME [nTPM]":"3.3","Cell RNA - U-138 MG [nTPM]":"5.7","Cell RNA - U-2 OS [nTPM]":"11.1","Cell RNA - U-2197 [nTPM]":"3.6","Cell RNA - U-251 MG [nTPM]":"7.1","Cell RNA - U-266\/70 [nTPM]":"6.8","Cell RNA - U-266\/84 [nTPM]":"20.2","Cell RNA - U-698 [nTPM]":"17.8","Cell RNA - U-87 MG [nTPM]":"3.3","Cell RNA - U-937 [nTPM]":"25.9","Cell RNA - WM-115 [nTPM]":"6.2","Blood RNA - basophil [nTPM]":"17.5","Blood RNA - classical monocyte [nTPM]":"25.7","Blood RNA - eosinophil [nTPM]":"73.5","Blood RNA - gdT-cell [nTPM]":"9.4","Blood RNA - intermediate monocyte [nTPM]":"35.3","Blood RNA - MAIT T-cell [nTPM]":"12.4","Blood RNA - memory B-cell [nTPM]":"13.5","Blood RNA - memory CD4 T-cell [nTPM]":"13.7","Blood RNA - memory CD8 T-cell [nTPM]":"12.9","Blood RNA - myeloid DC [nTPM]":"12.3","Blood RNA - naive B-cell [nTPM]":"11.1","Blood RNA - naive CD4 T-cell [nTPM]":"16.5","Blood RNA - naive CD8 T-cell [nTPM]":"12.6","Blood RNA - neutrophil [nTPM]":"134.1","Blood RNA - NK-cell [nTPM]":"17.8","Blood RNA - non-classical monocyte [nTPM]":"49.1","Blood RNA - plasmacytoid DC [nTPM]":"13.3","Blood RNA - T-reg [nTPM]":"15.7","Blood RNA - total PBMC [nTPM]":"19.1","Brain RNA - amygdala [nTPM]":"8.0","Brain RNA - basal ganglia [nTPM]":"8.2","Brain RNA - cerebellum [nTPM]":"9.6","Brain RNA - cerebral cortex [nTPM]":"12.7","Brain RNA - hippocampal formation [nTPM]":"8.0","Brain RNA - hypothalamus [nTPM]":"9.2","Brain RNA - medulla oblongata [nTPM]":"8.7","Brain RNA - midbrain [nTPM]":"9.3","Brain RNA - pons [nTPM]":"9.1","Brain RNA - spinal cord [nTPM]":"8.8","Brain RNA - thalamus [nTPM]":"8.7","Brain RNA - white matter [nTPM]":"9.1","Single Cell Type RNA - Adipocytes [nTPM]":"11.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"44.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"20.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"63.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"35.9","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"32.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"58.6","Single Cell Type RNA - Club cells [nTPM]":"34.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"68.1","Single Cell Type RNA - dendritic cells [nTPM]":"10.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"64.6","Single Cell Type RNA - Ductal cells [nTPM]":"55.8","Single Cell Type RNA - Early spermatids [nTPM]":"2.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.8","Single Cell Type RNA - Endothelial cells [nTPM]":"10.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.6","Single Cell Type RNA - Erythroid cells [nTPM]":"36.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"75.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"37.1","Single Cell Type RNA - Fibroblasts [nTPM]":"13.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"39.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.0","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"7.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.8","Single Cell Type RNA - Hepatocytes [nTPM]":"205.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"45.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.7","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"22.1","Single Cell Type RNA - Langerhans cells [nTPM]":"34.8","Single Cell Type RNA - Late spermatids [nTPM]":"3.8","Single Cell Type RNA - Leydig cells [nTPM]":"13.7","Single Cell Type RNA - Macrophages [nTPM]":"29.3","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"150.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"35.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"75.3","Single Cell Type RNA - Paneth cells [nTPM]":"35.9","Single Cell Type RNA - Peritubular cells [nTPM]":"15.8","Single Cell Type RNA - Plasma cells [nTPM]":"13.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"101.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"201.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.5","Single Cell Type RNA - Spermatocytes [nTPM]":"6.7","Single Cell Type RNA - Spermatogonia [nTPM]":"8.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"253.8","Single Cell Type RNA - T-cells [nTPM]":"22.2","Single Cell Type RNA - Theca cells [nTPM]":"9.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.9","Single Cell Type RNA - Urothelial cells [nTPM]":"7.7"},{"Gene":"MTM1","Gene synonym":[],"Ensembl":"ENSG00000171100","Gene description":"Myotubularin 1","Uniprot":["Q13496"],"Chromosome":"X","Position":"150568621-150673143","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid metabolism","Protein transport","Transport"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"52.2","Oligodendrocytes":"47.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010008","HPA010665"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA010008":"AB_1079426","HPA010665":"AB_1079425"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.43e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.40e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.8","Tissue RNA - adrenal gland [nTPM]":"11.1","Tissue RNA - amygdala [nTPM]":"7.4","Tissue RNA - appendix [nTPM]":"9.7","Tissue RNA - basal ganglia [nTPM]":"8.3","Tissue RNA - bone marrow [nTPM]":"11.3","Tissue RNA - breast [nTPM]":"7.6","Tissue RNA - cerebellum [nTPM]":"8.0","Tissue RNA - cerebral cortex [nTPM]":"8.4","Tissue RNA - cervix [nTPM]":"5.7","Tissue RNA - choroid plexus [nTPM]":"6.1","Tissue RNA - colon [nTPM]":"19.8","Tissue RNA - duodenum [nTPM]":"11.7","Tissue RNA - endometrium 1 [nTPM]":"6.5","Tissue RNA - epididymis [nTPM]":"8.4","Tissue RNA - esophagus [nTPM]":"7.5","Tissue RNA - fallopian tube [nTPM]":"9.6","Tissue RNA - gallbladder [nTPM]":"7.1","Tissue RNA - heart muscle [nTPM]":"7.3","Tissue RNA - hippocampal formation [nTPM]":"6.9","Tissue RNA - hypothalamus [nTPM]":"8.5","Tissue RNA - kidney [nTPM]":"12.9","Tissue RNA - liver [nTPM]":"18.4","Tissue RNA - lung [nTPM]":"11.2","Tissue RNA - lymph node [nTPM]":"12.4","Tissue RNA - medulla oblongata [nTPM]":"7.8","Tissue RNA - midbrain [nTPM]":"8.6","Tissue RNA - ovary [nTPM]":"11.7","Tissue RNA - pancreas [nTPM]":"4.9","Tissue RNA - parathyroid gland [nTPM]":"16.0","Tissue RNA - pituitary gland [nTPM]":"3.8","Tissue RNA - placenta [nTPM]":"6.3","Tissue RNA - pons [nTPM]":"8.0","Tissue RNA - prostate [nTPM]":"8.0","Tissue RNA - rectum [nTPM]":"19.2","Tissue RNA - retina [nTPM]":"5.4","Tissue RNA - salivary gland [nTPM]":"6.3","Tissue RNA - seminal vesicle [nTPM]":"10.7","Tissue RNA - skeletal muscle [nTPM]":"11.8","Tissue RNA - skin 1 [nTPM]":"8.2","Tissue RNA - small intestine [nTPM]":"12.1","Tissue RNA - smooth muscle [nTPM]":"6.9","Tissue RNA - spinal cord [nTPM]":"7.7","Tissue RNA - spleen [nTPM]":"11.9","Tissue RNA - stomach 1 [nTPM]":"7.8","Tissue RNA - testis [nTPM]":"11.5","Tissue RNA - thalamus [nTPM]":"8.8","Tissue RNA - thymus [nTPM]":"8.4","Tissue RNA - thyroid gland [nTPM]":"11.2","Tissue RNA - tongue [nTPM]":"10.1","Tissue RNA - tonsil [nTPM]":"9.7","Tissue RNA - urinary bladder [nTPM]":"7.1","Tissue RNA - vagina [nTPM]":"4.7","Tissue RNA - white matter [nTPM]":"8.8","Cell RNA - A-431 [nTPM]":"14.3","Cell RNA - A549 [nTPM]":"6.1","Cell RNA - AF22 [nTPM]":"8.5","Cell RNA - AN3-CA [nTPM]":"3.1","Cell RNA - ASC diff [nTPM]":"7.5","Cell RNA - ASC TERT1 [nTPM]":"7.3","Cell RNA - BEWO [nTPM]":"5.4","Cell RNA - BJ [nTPM]":"6.1","Cell RNA - BJ hTERT+ [nTPM]":"8.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.9","Cell RNA - CACO-2 [nTPM]":"4.7","Cell RNA - CAPAN-2 [nTPM]":"7.3","Cell RNA - Daudi [nTPM]":"22.2","Cell RNA - EFO-21 [nTPM]":"11.4","Cell RNA - fHDF\/TERT166 [nTPM]":"8.3","Cell RNA - GAMG [nTPM]":"21.9","Cell RNA - HaCaT [nTPM]":"9.9","Cell RNA - HAP1 [nTPM]":"6.1","Cell RNA - HBEC3-KT [nTPM]":"11.5","Cell RNA - HBF TERT88 [nTPM]":"8.6","Cell RNA - HDLM-2 [nTPM]":"6.4","Cell RNA - HEK 293 [nTPM]":"5.2","Cell RNA - HEL [nTPM]":"5.6","Cell RNA - HeLa [nTPM]":"5.4","Cell RNA - Hep G2 [nTPM]":"15.0","Cell RNA - HHSteC [nTPM]":"5.8","Cell RNA - HL-60 [nTPM]":"25.2","Cell RNA - HMC-1 [nTPM]":"19.1","Cell RNA - HSkMC [nTPM]":"4.5","Cell RNA - hTCEpi [nTPM]":"14.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.7","Cell RNA - hTERT-HME1 [nTPM]":"11.9","Cell RNA - hTERT-RPE1 [nTPM]":"6.9","Cell RNA - HUVEC TERT2 [nTPM]":"9.4","Cell RNA - JURKAT [nTPM]":"9.3","Cell RNA - K-562 [nTPM]":"3.9","Cell RNA - Karpas-707 [nTPM]":"19.8","Cell RNA - LHCN-M2 [nTPM]":"8.8","Cell RNA - MCF7 [nTPM]":"4.5","Cell RNA - MOLT-4 [nTPM]":"6.9","Cell RNA - NB-4 [nTPM]":"25.2","Cell RNA - NTERA-2 [nTPM]":"4.3","Cell RNA - OE19 [nTPM]":"13.4","Cell RNA - PC-3 [nTPM]":"7.4","Cell RNA - REH [nTPM]":"8.0","Cell RNA - RH-30 [nTPM]":"4.9","Cell RNA - RPMI-8226 [nTPM]":"4.5","Cell RNA - RPTEC TERT1 [nTPM]":"11.7","Cell RNA - RT4 [nTPM]":"6.9","Cell RNA - SCLC-21H [nTPM]":"2.2","Cell RNA - SH-SY5Y [nTPM]":"2.4","Cell RNA - SiHa [nTPM]":"5.5","Cell RNA - SK-BR-3 [nTPM]":"11.3","Cell RNA - SK-MEL-30 [nTPM]":"8.5","Cell RNA - SuSa [nTPM]":"11.9","Cell RNA - T-47d [nTPM]":"4.1","Cell RNA - THP-1 [nTPM]":"35.2","Cell RNA - TIME [nTPM]":"8.2","Cell RNA - U-138 MG [nTPM]":"5.0","Cell RNA - U-2 OS [nTPM]":"3.1","Cell RNA - U-2197 [nTPM]":"12.4","Cell RNA - U-251 MG [nTPM]":"7.1","Cell RNA - U-266\/70 [nTPM]":"4.2","Cell RNA - U-266\/84 [nTPM]":"10.0","Cell RNA - U-698 [nTPM]":"20.3","Cell RNA - U-87 MG [nTPM]":"6.0","Cell RNA - U-937 [nTPM]":"14.8","Cell RNA - WM-115 [nTPM]":"8.0","Blood RNA - basophil [nTPM]":"34.8","Blood RNA - classical monocyte [nTPM]":"9.5","Blood RNA - eosinophil [nTPM]":"27.9","Blood RNA - gdT-cell [nTPM]":"2.0","Blood RNA - intermediate monocyte [nTPM]":"10.8","Blood RNA - MAIT T-cell [nTPM]":"6.8","Blood RNA - memory B-cell [nTPM]":"8.0","Blood RNA - memory CD4 T-cell [nTPM]":"9.6","Blood RNA - memory CD8 T-cell [nTPM]":"7.3","Blood RNA - myeloid DC [nTPM]":"12.0","Blood RNA - naive B-cell [nTPM]":"10.6","Blood RNA - naive CD4 T-cell [nTPM]":"9.0","Blood RNA - naive CD8 T-cell [nTPM]":"5.4","Blood RNA - neutrophil [nTPM]":"11.6","Blood RNA - NK-cell [nTPM]":"14.6","Blood RNA - non-classical monocyte [nTPM]":"9.8","Blood RNA - plasmacytoid DC [nTPM]":"7.4","Blood RNA - T-reg [nTPM]":"12.2","Blood RNA - total PBMC [nTPM]":"7.1","Brain RNA - amygdala [nTPM]":"7.4","Brain RNA - basal ganglia [nTPM]":"8.3","Brain RNA - cerebellum [nTPM]":"8.0","Brain RNA - cerebral cortex [nTPM]":"8.4","Brain RNA - hippocampal formation [nTPM]":"6.9","Brain RNA - hypothalamus [nTPM]":"8.5","Brain RNA - medulla oblongata [nTPM]":"7.8","Brain RNA - midbrain [nTPM]":"8.6","Brain RNA - pons [nTPM]":"8.0","Brain RNA - spinal cord [nTPM]":"7.7","Brain RNA - thalamus [nTPM]":"8.8","Brain RNA - white matter [nTPM]":"8.8","Single Cell Type RNA - Adipocytes [nTPM]":"9.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.0","Single Cell Type RNA - Astrocytes [nTPM]":"52.2","Single Cell Type RNA - B-cells [nTPM]":"13.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"6.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.1","Single Cell Type RNA - dendritic cells [nTPM]":"8.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"33.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.4","Single Cell Type RNA - Early spermatids [nTPM]":"35.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.0","Single Cell Type RNA - Endothelial cells [nTPM]":"11.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"44.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.8","Single Cell Type RNA - Fibroblasts [nTPM]":"6.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.8","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"3.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.4","Single Cell Type RNA - Hepatocytes [nTPM]":"13.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"41.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.7","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"16.3","Single Cell Type RNA - Langerhans cells [nTPM]":"10.4","Single Cell Type RNA - Late spermatids [nTPM]":"18.8","Single Cell Type RNA - Leydig cells [nTPM]":"6.2","Single Cell Type RNA - Macrophages [nTPM]":"13.0","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"24.4","Single Cell Type RNA - monocytes [nTPM]":"12.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"27.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"47.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.7","Single Cell Type RNA - Paneth cells [nTPM]":"9.5","Single Cell Type RNA - Peritubular cells [nTPM]":"12.8","Single Cell Type RNA - Plasma cells [nTPM]":"8.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.9","Single Cell Type RNA - Spermatocytes [nTPM]":"5.1","Single Cell Type RNA - Spermatogonia [nTPM]":"4.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"19.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.3","Single Cell Type RNA - T-cells [nTPM]":"12.8","Single Cell Type RNA - Theca cells [nTPM]":"4.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.8","Single Cell Type RNA - Urothelial cells [nTPM]":"9.7"},{"Gene":"MTMR2","Gene synonym":["CMT4B","KIAA1073"],"Ensembl":"ENSG00000087053","Gene description":"Myotubularin related protein 2","Uniprot":["Q13614"],"Chromosome":"11","Position":"95821766-95925315","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"120.1","Oligodendrocytes":"226.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049831"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA049831":"AB_2680904"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.81e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.61e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.60e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.03e-3"},"Tissue RNA - adipose tissue [nTPM]":"14.7","Tissue RNA - adrenal gland [nTPM]":"9.3","Tissue RNA - amygdala [nTPM]":"11.0","Tissue RNA - appendix [nTPM]":"11.2","Tissue RNA - basal ganglia [nTPM]":"16.8","Tissue RNA - bone marrow [nTPM]":"4.4","Tissue RNA - breast [nTPM]":"11.8","Tissue RNA - cerebellum [nTPM]":"16.3","Tissue RNA - cerebral cortex [nTPM]":"18.3","Tissue RNA - cervix [nTPM]":"12.2","Tissue RNA - choroid plexus [nTPM]":"12.2","Tissue RNA - colon [nTPM]":"12.9","Tissue RNA - duodenum [nTPM]":"7.1","Tissue RNA - endometrium 1 [nTPM]":"12.3","Tissue RNA - epididymis [nTPM]":"6.2","Tissue RNA - esophagus [nTPM]":"14.7","Tissue RNA - fallopian tube [nTPM]":"12.4","Tissue RNA - gallbladder [nTPM]":"14.3","Tissue RNA - heart muscle [nTPM]":"13.5","Tissue RNA - hippocampal formation [nTPM]":"10.8","Tissue RNA - hypothalamus [nTPM]":"14.3","Tissue RNA - kidney [nTPM]":"16.4","Tissue RNA - liver [nTPM]":"4.3","Tissue RNA - lung [nTPM]":"12.3","Tissue RNA - lymph node [nTPM]":"9.5","Tissue RNA - medulla oblongata [nTPM]":"15.1","Tissue RNA - midbrain [nTPM]":"14.4","Tissue RNA - ovary [nTPM]":"11.5","Tissue RNA - pancreas [nTPM]":"7.8","Tissue RNA - parathyroid gland [nTPM]":"12.7","Tissue RNA - pituitary gland [nTPM]":"6.4","Tissue RNA - placenta [nTPM]":"24.5","Tissue RNA - pons [nTPM]":"15.8","Tissue RNA - prostate [nTPM]":"16.1","Tissue RNA - rectum [nTPM]":"13.9","Tissue RNA - retina [nTPM]":"18.6","Tissue RNA - salivary gland [nTPM]":"20.5","Tissue RNA - seminal vesicle [nTPM]":"11.4","Tissue RNA - skeletal muscle [nTPM]":"6.2","Tissue RNA - skin 1 [nTPM]":"8.2","Tissue RNA - small intestine [nTPM]":"8.3","Tissue RNA - smooth muscle [nTPM]":"18.0","Tissue RNA - spinal cord [nTPM]":"13.5","Tissue RNA - spleen [nTPM]":"8.6","Tissue RNA - stomach 1 [nTPM]":"13.0","Tissue RNA - testis [nTPM]":"31.0","Tissue RNA - thalamus [nTPM]":"14.1","Tissue RNA - thymus [nTPM]":"15.1","Tissue RNA - thyroid gland [nTPM]":"9.9","Tissue RNA - tongue [nTPM]":"8.9","Tissue RNA - tonsil [nTPM]":"12.1","Tissue RNA - urinary bladder [nTPM]":"15.2","Tissue RNA - vagina [nTPM]":"10.4","Tissue RNA - white matter [nTPM]":"22.4","Cell RNA - A-431 [nTPM]":"24.1","Cell RNA - A549 [nTPM]":"25.3","Cell RNA - AF22 [nTPM]":"54.1","Cell RNA - AN3-CA [nTPM]":"39.2","Cell RNA - ASC diff [nTPM]":"19.2","Cell RNA - ASC TERT1 [nTPM]":"29.0","Cell RNA - BEWO [nTPM]":"47.5","Cell RNA - BJ [nTPM]":"43.3","Cell RNA - BJ hTERT+ [nTPM]":"37.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"42.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"37.8","Cell RNA - CACO-2 [nTPM]":"57.3","Cell RNA - CAPAN-2 [nTPM]":"47.1","Cell RNA - Daudi [nTPM]":"16.2","Cell RNA - EFO-21 [nTPM]":"50.3","Cell RNA - fHDF\/TERT166 [nTPM]":"45.5","Cell RNA - GAMG [nTPM]":"35.9","Cell RNA - HaCaT [nTPM]":"30.9","Cell RNA - HAP1 [nTPM]":"47.7","Cell RNA - HBEC3-KT [nTPM]":"48.2","Cell RNA - HBF TERT88 [nTPM]":"38.9","Cell RNA - HDLM-2 [nTPM]":"30.8","Cell RNA - HEK 293 [nTPM]":"21.3","Cell RNA - HEL [nTPM]":"31.5","Cell RNA - HeLa [nTPM]":"55.0","Cell RNA - Hep G2 [nTPM]":"33.0","Cell RNA - HHSteC [nTPM]":"42.8","Cell RNA - HL-60 [nTPM]":"59.3","Cell RNA - HMC-1 [nTPM]":"26.7","Cell RNA - HSkMC [nTPM]":"24.0","Cell RNA - hTCEpi [nTPM]":"31.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"56.6","Cell RNA - hTERT-HME1 [nTPM]":"54.5","Cell RNA - hTERT-RPE1 [nTPM]":"41.8","Cell RNA - HUVEC TERT2 [nTPM]":"64.4","Cell RNA - JURKAT [nTPM]":"35.4","Cell RNA - K-562 [nTPM]":"44.7","Cell RNA - Karpas-707 [nTPM]":"14.2","Cell RNA - LHCN-M2 [nTPM]":"39.6","Cell RNA - MCF7 [nTPM]":"17.9","Cell RNA - MOLT-4 [nTPM]":"29.0","Cell RNA - NB-4 [nTPM]":"27.2","Cell RNA - NTERA-2 [nTPM]":"46.6","Cell RNA - OE19 [nTPM]":"59.0","Cell RNA - PC-3 [nTPM]":"34.9","Cell RNA - REH [nTPM]":"23.2","Cell RNA - RH-30 [nTPM]":"32.2","Cell RNA - RPMI-8226 [nTPM]":"16.8","Cell RNA - RPTEC TERT1 [nTPM]":"43.9","Cell RNA - RT4 [nTPM]":"125.0","Cell RNA - SCLC-21H [nTPM]":"35.6","Cell RNA - SH-SY5Y [nTPM]":"40.6","Cell RNA - SiHa [nTPM]":"43.6","Cell RNA - SK-BR-3 [nTPM]":"36.4","Cell RNA - SK-MEL-30 [nTPM]":"19.2","Cell RNA - SuSa [nTPM]":"35.1","Cell RNA - T-47d [nTPM]":"27.6","Cell RNA - THP-1 [nTPM]":"26.5","Cell RNA - TIME [nTPM]":"64.4","Cell RNA - U-138 MG [nTPM]":"47.7","Cell RNA - U-2 OS [nTPM]":"45.1","Cell RNA - U-2197 [nTPM]":"34.4","Cell RNA - U-251 MG [nTPM]":"41.1","Cell RNA - U-266\/70 [nTPM]":"13.1","Cell RNA - U-266\/84 [nTPM]":"42.4","Cell RNA - U-698 [nTPM]":"14.3","Cell RNA - U-87 MG [nTPM]":"20.4","Cell RNA - U-937 [nTPM]":"15.6","Cell RNA - WM-115 [nTPM]":"50.6","Blood RNA - basophil [nTPM]":"9.8","Blood RNA - classical monocyte [nTPM]":"3.9","Blood RNA - eosinophil [nTPM]":"1.7","Blood RNA - gdT-cell [nTPM]":"12.4","Blood RNA - intermediate monocyte [nTPM]":"4.7","Blood RNA - MAIT T-cell [nTPM]":"13.4","Blood RNA - memory B-cell [nTPM]":"5.8","Blood RNA - memory CD4 T-cell [nTPM]":"7.9","Blood RNA - memory CD8 T-cell [nTPM]":"15.7","Blood RNA - myeloid DC [nTPM]":"7.6","Blood RNA - naive B-cell [nTPM]":"4.9","Blood RNA - naive CD4 T-cell [nTPM]":"4.0","Blood RNA - naive CD8 T-cell [nTPM]":"11.3","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"14.1","Blood RNA - non-classical monocyte [nTPM]":"7.2","Blood RNA - plasmacytoid DC [nTPM]":"3.7","Blood RNA - T-reg [nTPM]":"8.1","Blood RNA - total PBMC [nTPM]":"7.8","Brain RNA - amygdala [nTPM]":"11.0","Brain RNA - basal ganglia [nTPM]":"16.8","Brain RNA - cerebellum [nTPM]":"16.3","Brain RNA - cerebral cortex [nTPM]":"18.3","Brain RNA - hippocampal formation [nTPM]":"10.8","Brain RNA - hypothalamus [nTPM]":"14.3","Brain RNA - medulla oblongata [nTPM]":"15.1","Brain RNA - midbrain [nTPM]":"14.4","Brain RNA - pons [nTPM]":"15.8","Brain RNA - spinal cord [nTPM]":"13.5","Brain RNA - thalamus [nTPM]":"14.1","Brain RNA - white matter [nTPM]":"22.4","Single Cell Type RNA - Adipocytes [nTPM]":"19.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.6","Single Cell Type RNA - Astrocytes [nTPM]":"28.7","Single Cell Type RNA - B-cells [nTPM]":"9.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"11.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.0","Single Cell Type RNA - dendritic cells [nTPM]":"8.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"17.8","Single Cell Type RNA - Early spermatids [nTPM]":"74.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.1","Single Cell Type RNA - Endothelial cells [nTPM]":"20.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.2","Single Cell Type RNA - Erythroid cells [nTPM]":"12.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"69.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"34.3","Single Cell Type RNA - Fibroblasts [nTPM]":"17.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.7","Single Cell Type RNA - granulocytes [nTPM]":"19.0","Single Cell Type RNA - Granulosa cells [nTPM]":"49.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"1.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.8","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"10.3","Single Cell Type RNA - Langerhans cells [nTPM]":"8.2","Single Cell Type RNA - Late spermatids [nTPM]":"120.1","Single Cell Type RNA - Leydig cells [nTPM]":"11.1","Single Cell Type RNA - Macrophages [nTPM]":"8.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"40.3","Single Cell Type RNA - monocytes [nTPM]":"6.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"63.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"226.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.7","Single Cell Type RNA - Paneth cells [nTPM]":"4.7","Single Cell Type RNA - Peritubular cells [nTPM]":"12.0","Single Cell Type RNA - Plasma cells [nTPM]":"7.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"29.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"29.0","Single Cell Type RNA - Spermatocytes [nTPM]":"46.8","Single Cell Type RNA - Spermatogonia [nTPM]":"19.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.0","Single Cell Type RNA - T-cells [nTPM]":"8.8","Single Cell Type RNA - Theca cells [nTPM]":"12.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.6","Single Cell Type RNA - Urothelial cells [nTPM]":"15.6"},{"Gene":"MTPAP","Gene synonym":["FLJ10486","PAPD1","SPAX4","TENT6"],"Ensembl":"ENSG00000107951","Gene description":"Mitochondrial poly(A) polymerase","Uniprot":["Q9NVV4"],"Chromosome":"10","Position":"30309801-30374448","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["mRNA processing","Transcription"],"Molecular function":["Nucleotidyltransferase","RNA-binding","Transferase"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"36.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Early spermatids":"240.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038620","HPA058232"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 23: Spermatids - Flagellum & Golgi organization","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA038620":"AB_10673015","HPA058232":"AB_2683646"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.20e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.9","Tissue RNA - adrenal gland [nTPM]":"7.4","Tissue RNA - amygdala [nTPM]":"4.9","Tissue RNA - appendix [nTPM]":"10.3","Tissue RNA - basal ganglia [nTPM]":"4.8","Tissue RNA - bone marrow [nTPM]":"36.8","Tissue RNA - breast [nTPM]":"9.7","Tissue RNA - cerebellum [nTPM]":"12.6","Tissue RNA - cerebral cortex [nTPM]":"6.7","Tissue RNA - cervix [nTPM]":"6.1","Tissue RNA - choroid plexus [nTPM]":"3.1","Tissue RNA - colon [nTPM]":"9.6","Tissue RNA - duodenum [nTPM]":"10.6","Tissue RNA - endometrium 1 [nTPM]":"9.0","Tissue RNA - epididymis [nTPM]":"6.2","Tissue RNA - esophagus [nTPM]":"8.3","Tissue RNA - fallopian tube [nTPM]":"6.6","Tissue RNA - gallbladder [nTPM]":"5.2","Tissue RNA - heart muscle [nTPM]":"8.8","Tissue RNA - hippocampal formation [nTPM]":"4.8","Tissue RNA - hypothalamus [nTPM]":"4.3","Tissue RNA - kidney [nTPM]":"9.6","Tissue RNA - liver [nTPM]":"10.6","Tissue RNA - lung [nTPM]":"6.3","Tissue RNA - lymph node [nTPM]":"10.7","Tissue RNA - medulla oblongata [nTPM]":"3.4","Tissue RNA - midbrain [nTPM]":"3.5","Tissue RNA - ovary [nTPM]":"8.2","Tissue RNA - pancreas [nTPM]":"10.0","Tissue RNA - parathyroid gland [nTPM]":"8.4","Tissue RNA - pituitary gland [nTPM]":"2.7","Tissue RNA - placenta [nTPM]":"9.6","Tissue RNA - pons [nTPM]":"3.9","Tissue RNA - prostate [nTPM]":"7.2","Tissue RNA - rectum [nTPM]":"11.0","Tissue RNA - retina [nTPM]":"7.1","Tissue RNA - salivary gland [nTPM]":"8.0","Tissue RNA - seminal vesicle [nTPM]":"4.9","Tissue RNA - skeletal muscle [nTPM]":"13.2","Tissue RNA - skin 1 [nTPM]":"8.4","Tissue RNA - small intestine [nTPM]":"9.0","Tissue RNA - smooth muscle [nTPM]":"9.1","Tissue RNA - spinal cord [nTPM]":"3.2","Tissue RNA - spleen [nTPM]":"9.3","Tissue RNA - stomach 1 [nTPM]":"7.1","Tissue RNA - testis [nTPM]":"5.1","Tissue RNA - thalamus [nTPM]":"3.6","Tissue RNA - thymus [nTPM]":"9.2","Tissue RNA - thyroid gland [nTPM]":"10.2","Tissue RNA - tongue [nTPM]":"12.0","Tissue RNA - tonsil [nTPM]":"10.3","Tissue RNA - urinary bladder [nTPM]":"8.1","Tissue RNA - vagina [nTPM]":"5.2","Tissue RNA - white matter [nTPM]":"6.2","Cell RNA - A-431 [nTPM]":"26.0","Cell RNA - A549 [nTPM]":"25.3","Cell RNA - AF22 [nTPM]":"15.8","Cell RNA - AN3-CA [nTPM]":"23.0","Cell RNA - ASC diff [nTPM]":"15.2","Cell RNA - ASC TERT1 [nTPM]":"14.2","Cell RNA - BEWO [nTPM]":"20.6","Cell RNA - BJ [nTPM]":"17.6","Cell RNA - BJ hTERT+ [nTPM]":"6.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"18.4","Cell RNA - CACO-2 [nTPM]":"27.0","Cell RNA - CAPAN-2 [nTPM]":"35.4","Cell RNA - Daudi [nTPM]":"36.9","Cell RNA - EFO-21 [nTPM]":"12.3","Cell RNA - fHDF\/TERT166 [nTPM]":"11.7","Cell RNA - GAMG [nTPM]":"16.3","Cell RNA - HaCaT [nTPM]":"29.7","Cell RNA - HAP1 [nTPM]":"31.1","Cell RNA - HBEC3-KT [nTPM]":"20.7","Cell RNA - HBF TERT88 [nTPM]":"21.6","Cell RNA - HDLM-2 [nTPM]":"18.7","Cell RNA - HEK 293 [nTPM]":"24.0","Cell RNA - HEL [nTPM]":"37.3","Cell RNA - HeLa [nTPM]":"23.7","Cell RNA - Hep G2 [nTPM]":"27.5","Cell RNA - HHSteC [nTPM]":"16.0","Cell RNA - HL-60 [nTPM]":"24.6","Cell RNA - HMC-1 [nTPM]":"28.2","Cell RNA - HSkMC [nTPM]":"14.3","Cell RNA - hTCEpi [nTPM]":"19.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.9","Cell RNA - hTERT-HME1 [nTPM]":"11.7","Cell RNA - hTERT-RPE1 [nTPM]":"9.8","Cell RNA - HUVEC TERT2 [nTPM]":"19.6","Cell RNA - JURKAT [nTPM]":"34.0","Cell RNA - K-562 [nTPM]":"41.2","Cell RNA - Karpas-707 [nTPM]":"28.1","Cell RNA - LHCN-M2 [nTPM]":"13.5","Cell RNA - MCF7 [nTPM]":"21.8","Cell RNA - MOLT-4 [nTPM]":"29.8","Cell RNA - NB-4 [nTPM]":"21.8","Cell RNA - NTERA-2 [nTPM]":"10.8","Cell RNA - OE19 [nTPM]":"19.5","Cell RNA - PC-3 [nTPM]":"13.3","Cell RNA - REH [nTPM]":"29.6","Cell RNA - RH-30 [nTPM]":"27.9","Cell RNA - RPMI-8226 [nTPM]":"34.4","Cell RNA - RPTEC TERT1 [nTPM]":"16.2","Cell RNA - RT4 [nTPM]":"17.1","Cell RNA - SCLC-21H [nTPM]":"25.9","Cell RNA - SH-SY5Y [nTPM]":"20.8","Cell RNA - SiHa [nTPM]":"16.0","Cell RNA - SK-BR-3 [nTPM]":"16.4","Cell RNA - SK-MEL-30 [nTPM]":"24.7","Cell RNA - SuSa [nTPM]":"14.8","Cell RNA - T-47d [nTPM]":"15.8","Cell RNA - THP-1 [nTPM]":"15.6","Cell RNA - TIME [nTPM]":"18.7","Cell RNA - U-138 MG [nTPM]":"18.4","Cell RNA - U-2 OS [nTPM]":"23.8","Cell RNA - U-2197 [nTPM]":"26.0","Cell RNA - U-251 MG [nTPM]":"19.8","Cell RNA - U-266\/70 [nTPM]":"6.2","Cell RNA - U-266\/84 [nTPM]":"16.3","Cell RNA - U-698 [nTPM]":"50.8","Cell RNA - U-87 MG [nTPM]":"15.9","Cell RNA - U-937 [nTPM]":"44.5","Cell RNA - WM-115 [nTPM]":"6.6","Blood RNA - basophil [nTPM]":"27.4","Blood RNA - classical monocyte [nTPM]":"25.2","Blood RNA - eosinophil [nTPM]":"27.3","Blood RNA - gdT-cell [nTPM]":"21.7","Blood RNA - intermediate monocyte [nTPM]":"35.0","Blood RNA - MAIT T-cell [nTPM]":"23.0","Blood RNA - memory B-cell [nTPM]":"20.8","Blood RNA - memory CD4 T-cell [nTPM]":"20.4","Blood RNA - memory CD8 T-cell [nTPM]":"21.1","Blood RNA - myeloid DC [nTPM]":"33.0","Blood RNA - naive B-cell [nTPM]":"17.1","Blood RNA - naive CD4 T-cell [nTPM]":"21.6","Blood RNA - naive CD8 T-cell [nTPM]":"22.0","Blood RNA - neutrophil [nTPM]":"4.2","Blood RNA - NK-cell [nTPM]":"25.1","Blood RNA - non-classical monocyte [nTPM]":"27.9","Blood RNA - plasmacytoid DC [nTPM]":"17.3","Blood RNA - T-reg [nTPM]":"23.1","Blood RNA - total PBMC [nTPM]":"13.1","Brain RNA - amygdala [nTPM]":"4.9","Brain RNA - basal ganglia [nTPM]":"4.8","Brain RNA - cerebellum [nTPM]":"12.6","Brain RNA - cerebral cortex [nTPM]":"6.7","Brain RNA - hippocampal formation [nTPM]":"4.8","Brain RNA - hypothalamus [nTPM]":"4.3","Brain RNA - medulla oblongata [nTPM]":"3.4","Brain RNA - midbrain [nTPM]":"3.5","Brain RNA - pons [nTPM]":"3.9","Brain RNA - spinal cord [nTPM]":"3.2","Brain RNA - thalamus [nTPM]":"3.6","Brain RNA - white matter [nTPM]":"6.2","Single Cell Type RNA - Adipocytes [nTPM]":"12.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.4","Single Cell Type RNA - Astrocytes [nTPM]":"9.1","Single Cell Type RNA - B-cells [nTPM]":"11.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"25.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"9.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.1","Single Cell Type RNA - dendritic cells [nTPM]":"13.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"9.6","Single Cell Type RNA - Early spermatids [nTPM]":"240.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.8","Single Cell Type RNA - Endothelial cells [nTPM]":"12.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"16.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.0","Single Cell Type RNA - Fibroblasts [nTPM]":"12.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.5","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"18.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.5","Single Cell Type RNA - Hepatocytes [nTPM]":"14.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.6","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"15.8","Single Cell Type RNA - Langerhans cells [nTPM]":"13.6","Single Cell Type RNA - Late spermatids [nTPM]":"34.3","Single Cell Type RNA - Leydig cells [nTPM]":"12.2","Single Cell Type RNA - Macrophages [nTPM]":"10.8","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"14.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.9","Single Cell Type RNA - Paneth cells [nTPM]":"5.2","Single Cell Type RNA - Peritubular cells [nTPM]":"16.6","Single Cell Type RNA - Plasma cells [nTPM]":"5.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.8","Single Cell Type RNA - Spermatocytes [nTPM]":"25.3","Single Cell Type RNA - Spermatogonia [nTPM]":"19.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.5","Single Cell Type RNA - T-cells [nTPM]":"8.8","Single Cell Type RNA - Theca cells [nTPM]":"12.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.4","Single Cell Type RNA - Urothelial cells [nTPM]":"16.6"},{"Gene":"MTRR","Gene synonym":["cblE"],"Ensembl":"ENSG00000124275","Gene description":"5-methyltetrahydrofolate-homocysteine methyltransferase reductase","Uniprot":["Q9UBK8"],"Chromosome":"5","Position":"7851186-7906025","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Amino-acid biosynthesis","Methionine biosynthesis"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"70.1","Late spermatids":"99.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038113"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Intermediate filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 11: Alveolar cells - Smell perception","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Intermediate filaments"],"Antibody RRID":{"HPA038113":"AB_10671520"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.60e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Tissue RNA - adipose tissue [nTPM]":"11.2","Tissue RNA - adrenal gland [nTPM]":"10.6","Tissue RNA - amygdala [nTPM]":"5.1","Tissue RNA - appendix [nTPM]":"9.5","Tissue RNA - basal ganglia [nTPM]":"11.2","Tissue RNA - bone marrow [nTPM]":"5.7","Tissue RNA - breast [nTPM]":"6.3","Tissue RNA - cerebellum [nTPM]":"10.1","Tissue RNA - cerebral cortex [nTPM]":"10.9","Tissue RNA - cervix [nTPM]":"7.2","Tissue RNA - choroid plexus [nTPM]":"3.4","Tissue RNA - colon [nTPM]":"8.3","Tissue RNA - duodenum [nTPM]":"8.9","Tissue RNA - endometrium 1 [nTPM]":"11.7","Tissue RNA - epididymis [nTPM]":"12.3","Tissue RNA - esophagus [nTPM]":"9.3","Tissue RNA - fallopian tube [nTPM]":"9.6","Tissue RNA - gallbladder [nTPM]":"11.8","Tissue RNA - heart muscle [nTPM]":"14.4","Tissue RNA - hippocampal formation [nTPM]":"6.5","Tissue RNA - hypothalamus [nTPM]":"9.0","Tissue RNA - kidney [nTPM]":"18.7","Tissue RNA - liver [nTPM]":"19.4","Tissue RNA - lung [nTPM]":"13.1","Tissue RNA - lymph node [nTPM]":"11.1","Tissue RNA - medulla oblongata [nTPM]":"10.9","Tissue RNA - midbrain [nTPM]":"10.4","Tissue RNA - ovary [nTPM]":"11.4","Tissue RNA - pancreas [nTPM]":"11.9","Tissue RNA - parathyroid gland [nTPM]":"12.8","Tissue RNA - pituitary gland [nTPM]":"6.7","Tissue RNA - placenta [nTPM]":"10.8","Tissue RNA - pons [nTPM]":"10.6","Tissue RNA - prostate [nTPM]":"9.0","Tissue RNA - rectum [nTPM]":"10.1","Tissue RNA - retina [nTPM]":"19.2","Tissue RNA - salivary gland [nTPM]":"10.5","Tissue RNA - seminal vesicle [nTPM]":"7.1","Tissue RNA - skeletal muscle [nTPM]":"28.9","Tissue RNA - skin 1 [nTPM]":"9.1","Tissue RNA - small intestine [nTPM]":"10.2","Tissue RNA - smooth muscle [nTPM]":"12.0","Tissue RNA - spinal cord [nTPM]":"8.2","Tissue RNA - spleen [nTPM]":"6.7","Tissue RNA - stomach 1 [nTPM]":"6.7","Tissue RNA - testis [nTPM]":"7.1","Tissue RNA - thalamus [nTPM]":"9.3","Tissue RNA - thymus [nTPM]":"7.5","Tissue RNA - thyroid gland [nTPM]":"9.0","Tissue RNA - tongue [nTPM]":"32.9","Tissue RNA - tonsil [nTPM]":"10.6","Tissue RNA - urinary bladder [nTPM]":"14.4","Tissue RNA - vagina [nTPM]":"5.5","Tissue RNA - white matter [nTPM]":"20.0","Cell RNA - A-431 [nTPM]":"19.3","Cell RNA - A549 [nTPM]":"18.1","Cell RNA - AF22 [nTPM]":"10.2","Cell RNA - AN3-CA [nTPM]":"20.0","Cell RNA - ASC diff [nTPM]":"34.0","Cell RNA - ASC TERT1 [nTPM]":"13.6","Cell RNA - BEWO [nTPM]":"25.1","Cell RNA - BJ [nTPM]":"31.1","Cell RNA - BJ hTERT+ [nTPM]":"18.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.4","Cell RNA - CACO-2 [nTPM]":"27.8","Cell RNA - CAPAN-2 [nTPM]":"15.1","Cell RNA - Daudi [nTPM]":"32.6","Cell RNA - EFO-21 [nTPM]":"27.9","Cell RNA - fHDF\/TERT166 [nTPM]":"24.6","Cell RNA - GAMG [nTPM]":"27.4","Cell RNA - HaCaT [nTPM]":"11.8","Cell RNA - HAP1 [nTPM]":"17.0","Cell RNA - HBEC3-KT [nTPM]":"14.2","Cell RNA - HBF TERT88 [nTPM]":"27.9","Cell RNA - HDLM-2 [nTPM]":"22.9","Cell RNA - HEK 293 [nTPM]":"15.8","Cell RNA - HEL [nTPM]":"14.6","Cell RNA - HeLa [nTPM]":"62.0","Cell RNA - Hep G2 [nTPM]":"15.3","Cell RNA - HHSteC [nTPM]":"21.9","Cell RNA - HL-60 [nTPM]":"23.4","Cell RNA - HMC-1 [nTPM]":"6.8","Cell RNA - HSkMC [nTPM]":"18.3","Cell RNA - hTCEpi [nTPM]":"11.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"24.6","Cell RNA - hTERT-HME1 [nTPM]":"18.4","Cell RNA - hTERT-RPE1 [nTPM]":"20.4","Cell RNA - HUVEC TERT2 [nTPM]":"10.4","Cell RNA - JURKAT [nTPM]":"8.0","Cell RNA - K-562 [nTPM]":"21.9","Cell RNA - Karpas-707 [nTPM]":"24.2","Cell RNA - LHCN-M2 [nTPM]":"9.8","Cell RNA - MCF7 [nTPM]":"4.2","Cell RNA - MOLT-4 [nTPM]":"14.2","Cell RNA - NB-4 [nTPM]":"11.7","Cell RNA - NTERA-2 [nTPM]":"7.3","Cell RNA - OE19 [nTPM]":"29.4","Cell RNA - PC-3 [nTPM]":"19.0","Cell RNA - REH [nTPM]":"12.4","Cell RNA - RH-30 [nTPM]":"9.5","Cell RNA - RPMI-8226 [nTPM]":"14.1","Cell RNA - RPTEC TERT1 [nTPM]":"16.2","Cell RNA - RT4 [nTPM]":"16.0","Cell RNA - SCLC-21H [nTPM]":"14.0","Cell RNA - SH-SY5Y [nTPM]":"2.5","Cell RNA - SiHa [nTPM]":"51.6","Cell RNA - SK-BR-3 [nTPM]":"33.7","Cell RNA - SK-MEL-30 [nTPM]":"28.6","Cell RNA - SuSa [nTPM]":"18.1","Cell RNA - T-47d [nTPM]":"10.7","Cell RNA - THP-1 [nTPM]":"17.5","Cell RNA - TIME [nTPM]":"14.6","Cell RNA - U-138 MG [nTPM]":"31.9","Cell RNA - U-2 OS [nTPM]":"19.7","Cell RNA - U-2197 [nTPM]":"24.1","Cell RNA - U-251 MG [nTPM]":"22.7","Cell RNA - U-266\/70 [nTPM]":"34.7","Cell RNA - U-266\/84 [nTPM]":"13.5","Cell RNA - U-698 [nTPM]":"27.3","Cell RNA - U-87 MG [nTPM]":"23.1","Cell RNA - U-937 [nTPM]":"50.5","Cell RNA - WM-115 [nTPM]":"19.1","Blood RNA - basophil [nTPM]":"5.3","Blood RNA - classical monocyte [nTPM]":"4.0","Blood RNA - eosinophil [nTPM]":"3.0","Blood RNA - gdT-cell [nTPM]":"4.1","Blood RNA - intermediate monocyte [nTPM]":"5.5","Blood RNA - MAIT T-cell [nTPM]":"7.0","Blood RNA - memory B-cell [nTPM]":"3.3","Blood RNA - memory CD4 T-cell [nTPM]":"6.5","Blood RNA - memory CD8 T-cell [nTPM]":"5.7","Blood RNA - myeloid DC [nTPM]":"3.6","Blood RNA - naive B-cell [nTPM]":"3.3","Blood RNA - naive CD4 T-cell [nTPM]":"4.1","Blood RNA - naive CD8 T-cell [nTPM]":"3.6","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"3.1","Blood RNA - non-classical monocyte [nTPM]":"4.4","Blood RNA - plasmacytoid DC [nTPM]":"2.3","Blood RNA - T-reg [nTPM]":"9.1","Blood RNA - total PBMC [nTPM]":"3.3","Brain RNA - amygdala [nTPM]":"5.1","Brain RNA - basal ganglia [nTPM]":"11.2","Brain RNA - cerebellum [nTPM]":"10.1","Brain RNA - cerebral cortex [nTPM]":"10.9","Brain RNA - hippocampal formation [nTPM]":"6.5","Brain RNA - hypothalamus [nTPM]":"9.0","Brain RNA - medulla oblongata [nTPM]":"10.9","Brain RNA - midbrain [nTPM]":"10.4","Brain RNA - pons [nTPM]":"10.6","Brain RNA - spinal cord [nTPM]":"8.2","Brain RNA - thalamus [nTPM]":"9.3","Brain RNA - white matter [nTPM]":"20.0","Single Cell Type RNA - Adipocytes [nTPM]":"7.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"70.1","Single Cell Type RNA - Astrocytes [nTPM]":"10.1","Single Cell Type RNA - B-cells [nTPM]":"11.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"9.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.9","Single Cell Type RNA - dendritic cells [nTPM]":"11.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"10.2","Single Cell Type RNA - Early spermatids [nTPM]":"50.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.7","Single Cell Type RNA - Endothelial cells [nTPM]":"8.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"12.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.9","Single Cell Type RNA - Fibroblasts [nTPM]":"11.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.7","Single Cell Type RNA - granulocytes [nTPM]":"10.2","Single Cell Type RNA - Granulosa cells [nTPM]":"6.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.6","Single Cell Type RNA - Hepatocytes [nTPM]":"19.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"11.1","Single Cell Type RNA - Langerhans cells [nTPM]":"9.4","Single Cell Type RNA - Late spermatids [nTPM]":"99.2","Single Cell Type RNA - Leydig cells [nTPM]":"10.5","Single Cell Type RNA - Macrophages [nTPM]":"9.7","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"8.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"50.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.2","Single Cell Type RNA - Paneth cells [nTPM]":"6.0","Single Cell Type RNA - Peritubular cells [nTPM]":"11.7","Single Cell Type RNA - Plasma cells [nTPM]":"26.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"28.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.1","Single Cell Type RNA - Spermatocytes [nTPM]":"17.4","Single Cell Type RNA - Spermatogonia [nTPM]":"13.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.2","Single Cell Type RNA - T-cells [nTPM]":"13.8","Single Cell Type RNA - Theca cells [nTPM]":"11.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.4","Single Cell Type RNA - Urothelial cells [nTPM]":"8.7"},{"Gene":"MUSK","Gene synonym":[],"Ensembl":"ENSG00000030304","Gene description":"Muscle associated receptor tyrosine kinase","Uniprot":["O15146"],"Chromosome":"9","Position":"110668779-110806558","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Differentiation"],"Molecular function":["Developmental protein","Kinase","Muscle protein","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"6.2","skeletal muscle":"4.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"4.8","Leydig cells":"5.3","Oligodendrocytes":"17.0","Peritubular cells":"19.5","Skeletal myocytes":"23.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"16","RNA cell line specific nTPM":{"LHCN-M2":"24.7","RH-30":"23.7"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"5.0"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"1.5","Tissue RNA - appendix [nTPM]":"1.7","Tissue RNA - basal ganglia [nTPM]":"3.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.8","Tissue RNA - cerebral cortex [nTPM]":"1.5","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"1.6","Tissue RNA - colon [nTPM]":"1.9","Tissue RNA - duodenum [nTPM]":"1.1","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"1.4","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"1.5","Tissue RNA - hippocampal formation [nTPM]":"1.2","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"2.7","Tissue RNA - midbrain [nTPM]":"6.2","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"1.7","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"2.5","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"4.1","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"2.4","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"2.9","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"1.3","Tissue RNA - testis [nTPM]":"1.6","Tissue RNA - thalamus [nTPM]":"2.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"2.0","Tissue RNA - tonsil [nTPM]":"2.0","Tissue RNA - urinary bladder [nTPM]":"1.2","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"4.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.4","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"1.5","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.8","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"24.7","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"23.7","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.5","Brain RNA - basal ganglia [nTPM]":"3.0","Brain RNA - cerebellum [nTPM]":"0.8","Brain RNA - cerebral cortex [nTPM]":"1.5","Brain RNA - hippocampal formation [nTPM]":"1.2","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"2.7","Brain RNA - midbrain [nTPM]":"6.2","Brain RNA - pons [nTPM]":"1.7","Brain RNA - spinal cord [nTPM]":"2.9","Brain RNA - thalamus [nTPM]":"2.0","Brain RNA - white matter [nTPM]":"4.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"4.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"4.8","Single Cell Type RNA - Leydig cells [nTPM]":"5.3","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"19.5","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"MUTYH","Gene synonym":["MYH"],"Ensembl":"ENSG00000132781","Gene description":"MutY DNA glycosylase","Uniprot":["Q9UIF7"],"Chromosome":"1","Position":"45329163-45340893","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"40.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008732"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA008732":"AB_1854219"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.76e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.25e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-3"},"Tissue RNA - adipose tissue [nTPM]":"5.0","Tissue RNA - adrenal gland [nTPM]":"5.0","Tissue RNA - amygdala [nTPM]":"11.9","Tissue RNA - appendix [nTPM]":"5.5","Tissue RNA - basal ganglia [nTPM]":"12.7","Tissue RNA - bone marrow [nTPM]":"6.7","Tissue RNA - breast [nTPM]":"5.3","Tissue RNA - cerebellum [nTPM]":"16.7","Tissue RNA - cerebral cortex [nTPM]":"15.6","Tissue RNA - cervix [nTPM]":"7.6","Tissue RNA - choroid plexus [nTPM]":"10.6","Tissue RNA - colon [nTPM]":"6.0","Tissue RNA - duodenum [nTPM]":"6.4","Tissue RNA - endometrium 1 [nTPM]":"6.3","Tissue RNA - epididymis [nTPM]":"4.6","Tissue RNA - esophagus [nTPM]":"5.1","Tissue RNA - fallopian tube [nTPM]":"5.7","Tissue RNA - gallbladder [nTPM]":"4.2","Tissue RNA - heart muscle [nTPM]":"4.0","Tissue RNA - hippocampal formation [nTPM]":"11.6","Tissue RNA - hypothalamus [nTPM]":"11.9","Tissue RNA - kidney [nTPM]":"7.0","Tissue RNA - liver [nTPM]":"5.9","Tissue RNA - lung [nTPM]":"4.4","Tissue RNA - lymph node [nTPM]":"7.7","Tissue RNA - medulla oblongata [nTPM]":"12.8","Tissue RNA - midbrain [nTPM]":"12.4","Tissue RNA - ovary [nTPM]":"7.3","Tissue RNA - pancreas [nTPM]":"5.1","Tissue RNA - parathyroid gland [nTPM]":"5.1","Tissue RNA - pituitary gland [nTPM]":"5.9","Tissue RNA - placenta [nTPM]":"6.4","Tissue RNA - pons [nTPM]":"12.7","Tissue RNA - prostate [nTPM]":"5.8","Tissue RNA - rectum [nTPM]":"5.6","Tissue RNA - retina [nTPM]":"4.9","Tissue RNA - salivary gland [nTPM]":"4.5","Tissue RNA - seminal vesicle [nTPM]":"5.0","Tissue RNA - skeletal muscle [nTPM]":"5.6","Tissue RNA - skin 1 [nTPM]":"5.9","Tissue RNA - small intestine [nTPM]":"6.1","Tissue RNA - smooth muscle [nTPM]":"3.6","Tissue RNA - spinal cord [nTPM]":"11.7","Tissue RNA - spleen [nTPM]":"7.8","Tissue RNA - stomach 1 [nTPM]":"5.8","Tissue RNA - testis [nTPM]":"3.3","Tissue RNA - thalamus [nTPM]":"12.2","Tissue RNA - thymus [nTPM]":"9.8","Tissue RNA - thyroid gland [nTPM]":"6.6","Tissue RNA - tongue [nTPM]":"4.7","Tissue RNA - tonsil [nTPM]":"7.0","Tissue RNA - urinary bladder [nTPM]":"5.9","Tissue RNA - vagina [nTPM]":"5.8","Tissue RNA - white matter [nTPM]":"14.4","Cell RNA - A-431 [nTPM]":"7.9","Cell RNA - A549 [nTPM]":"6.9","Cell RNA - AF22 [nTPM]":"15.5","Cell RNA - AN3-CA [nTPM]":"10.5","Cell RNA - ASC diff [nTPM]":"11.3","Cell RNA - ASC TERT1 [nTPM]":"8.4","Cell RNA - BEWO [nTPM]":"26.6","Cell RNA - BJ [nTPM]":"5.7","Cell RNA - BJ hTERT+ [nTPM]":"7.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.2","Cell RNA - CACO-2 [nTPM]":"14.3","Cell RNA - CAPAN-2 [nTPM]":"11.2","Cell RNA - Daudi [nTPM]":"22.5","Cell RNA - EFO-21 [nTPM]":"9.0","Cell RNA - fHDF\/TERT166 [nTPM]":"3.6","Cell RNA - GAMG [nTPM]":"9.5","Cell RNA - HaCaT [nTPM]":"11.3","Cell RNA - HAP1 [nTPM]":"8.7","Cell RNA - HBEC3-KT [nTPM]":"11.0","Cell RNA - HBF TERT88 [nTPM]":"5.4","Cell RNA - HDLM-2 [nTPM]":"18.1","Cell RNA - HEK 293 [nTPM]":"7.0","Cell RNA - HEL [nTPM]":"10.2","Cell RNA - HeLa [nTPM]":"11.4","Cell RNA - Hep G2 [nTPM]":"10.5","Cell RNA - HHSteC [nTPM]":"10.0","Cell RNA - HL-60 [nTPM]":"9.4","Cell RNA - HMC-1 [nTPM]":"7.1","Cell RNA - HSkMC [nTPM]":"4.6","Cell RNA - hTCEpi [nTPM]":"10.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.0","Cell RNA - hTERT-HME1 [nTPM]":"25.7","Cell RNA - hTERT-RPE1 [nTPM]":"3.1","Cell RNA - HUVEC TERT2 [nTPM]":"8.6","Cell RNA - JURKAT [nTPM]":"28.6","Cell RNA - K-562 [nTPM]":"17.5","Cell RNA - Karpas-707 [nTPM]":"7.4","Cell RNA - LHCN-M2 [nTPM]":"5.0","Cell RNA - MCF7 [nTPM]":"13.3","Cell RNA - MOLT-4 [nTPM]":"27.3","Cell RNA - NB-4 [nTPM]":"8.7","Cell RNA - NTERA-2 [nTPM]":"39.6","Cell RNA - OE19 [nTPM]":"19.5","Cell RNA - PC-3 [nTPM]":"7.9","Cell RNA - REH [nTPM]":"36.2","Cell RNA - RH-30 [nTPM]":"12.6","Cell RNA - RPMI-8226 [nTPM]":"12.3","Cell RNA - RPTEC TERT1 [nTPM]":"6.1","Cell RNA - RT4 [nTPM]":"14.6","Cell RNA - SCLC-21H [nTPM]":"14.5","Cell RNA - SH-SY5Y [nTPM]":"11.8","Cell RNA - SiHa [nTPM]":"11.3","Cell RNA - SK-BR-3 [nTPM]":"8.7","Cell RNA - SK-MEL-30 [nTPM]":"18.2","Cell RNA - SuSa [nTPM]":"20.1","Cell RNA - T-47d [nTPM]":"6.7","Cell RNA - THP-1 [nTPM]":"11.1","Cell RNA - TIME [nTPM]":"4.9","Cell RNA - U-138 MG [nTPM]":"8.3","Cell RNA - U-2 OS [nTPM]":"6.2","Cell RNA - U-2197 [nTPM]":"7.2","Cell RNA - U-251 MG [nTPM]":"8.2","Cell RNA - U-266\/70 [nTPM]":"11.6","Cell RNA - U-266\/84 [nTPM]":"14.6","Cell RNA - U-698 [nTPM]":"13.3","Cell RNA - U-87 MG [nTPM]":"8.0","Cell RNA - U-937 [nTPM]":"14.6","Cell RNA - WM-115 [nTPM]":"7.5","Blood RNA - basophil [nTPM]":"1.6","Blood RNA - classical monocyte [nTPM]":"7.0","Blood RNA - eosinophil [nTPM]":"2.9","Blood RNA - gdT-cell [nTPM]":"11.5","Blood RNA - intermediate monocyte [nTPM]":"11.8","Blood RNA - MAIT T-cell [nTPM]":"17.2","Blood RNA - memory B-cell [nTPM]":"8.1","Blood RNA - memory CD4 T-cell [nTPM]":"11.8","Blood RNA - memory CD8 T-cell [nTPM]":"11.5","Blood RNA - myeloid DC [nTPM]":"8.1","Blood RNA - naive B-cell [nTPM]":"8.0","Blood RNA - naive CD4 T-cell [nTPM]":"12.7","Blood RNA - naive CD8 T-cell [nTPM]":"12.2","Blood RNA - neutrophil [nTPM]":"1.4","Blood RNA - NK-cell [nTPM]":"8.8","Blood RNA - non-classical monocyte [nTPM]":"9.1","Blood RNA - plasmacytoid DC [nTPM]":"6.5","Blood RNA - T-reg [nTPM]":"13.4","Blood RNA - total PBMC [nTPM]":"8.6","Brain RNA - amygdala [nTPM]":"11.9","Brain RNA - basal ganglia [nTPM]":"12.7","Brain RNA - cerebellum [nTPM]":"16.7","Brain RNA - cerebral cortex [nTPM]":"15.6","Brain RNA - hippocampal formation [nTPM]":"11.6","Brain RNA - hypothalamus [nTPM]":"11.9","Brain RNA - medulla oblongata [nTPM]":"12.8","Brain RNA - midbrain [nTPM]":"12.4","Brain RNA - pons [nTPM]":"12.7","Brain RNA - spinal cord [nTPM]":"11.7","Brain RNA - thalamus [nTPM]":"12.2","Brain RNA - white matter [nTPM]":"14.4","Single Cell Type RNA - Adipocytes [nTPM]":"10.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.6","Single Cell Type RNA - Astrocytes [nTPM]":"17.0","Single Cell Type RNA - B-cells [nTPM]":"12.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"15.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"6.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"40.2","Single Cell Type RNA - dendritic cells [nTPM]":"8.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.1","Single Cell Type RNA - Endothelial cells [nTPM]":"7.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.8","Single Cell Type RNA - Erythroid cells [nTPM]":"6.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.3","Single Cell Type RNA - Fibroblasts [nTPM]":"7.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.2","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"8.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.7","Single Cell Type RNA - Hepatocytes [nTPM]":"4.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.0","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.1","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"4.0","Single Cell Type RNA - Langerhans cells [nTPM]":"10.2","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"10.8","Single Cell Type RNA - Macrophages [nTPM]":"5.6","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"8.2","Single Cell Type RNA - Muller glia cells [nTPM]":"12.0","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.8","Single Cell Type RNA - Paneth cells [nTPM]":"16.4","Single Cell Type RNA - Peritubular cells [nTPM]":"12.0","Single Cell Type RNA - Plasma cells [nTPM]":"7.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"20.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.6","Single Cell Type RNA - Spermatocytes [nTPM]":"10.5","Single Cell Type RNA - Spermatogonia [nTPM]":"11.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.2","Single Cell Type RNA - T-cells [nTPM]":"13.9","Single Cell Type RNA - Theca cells [nTPM]":"9.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.5","Single Cell Type RNA - Urothelial cells [nTPM]":"8.0"},{"Gene":"MVD","Gene synonym":["MPD"],"Ensembl":"ENSG00000167508","Gene description":"Mevalonate diphosphate decarboxylase","Uniprot":["P53602"],"Chromosome":"16","Position":"88651935-88663161","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Lyase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"147.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041404","HPA048250"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cell Junctions","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA041404":"AB_2677457","HPA048250":"AB_2680329"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.17e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-2"},"Tissue RNA - adipose tissue [nTPM]":"20.3","Tissue RNA - adrenal gland [nTPM]":"51.1","Tissue RNA - amygdala [nTPM]":"24.2","Tissue RNA - appendix [nTPM]":"15.7","Tissue RNA - basal ganglia [nTPM]":"27.5","Tissue RNA - bone marrow [nTPM]":"7.0","Tissue RNA - breast [nTPM]":"16.4","Tissue RNA - cerebellum [nTPM]":"26.2","Tissue RNA - cerebral cortex [nTPM]":"37.5","Tissue RNA - cervix [nTPM]":"30.5","Tissue RNA - choroid plexus [nTPM]":"19.3","Tissue RNA - colon [nTPM]":"32.3","Tissue RNA - duodenum [nTPM]":"35.1","Tissue RNA - endometrium 1 [nTPM]":"20.3","Tissue RNA - epididymis [nTPM]":"2.2","Tissue RNA - esophagus [nTPM]":"77.8","Tissue RNA - fallopian tube [nTPM]":"13.5","Tissue RNA - gallbladder [nTPM]":"4.9","Tissue RNA - heart muscle [nTPM]":"22.8","Tissue RNA - hippocampal formation [nTPM]":"24.7","Tissue RNA - hypothalamus [nTPM]":"27.8","Tissue RNA - kidney [nTPM]":"28.8","Tissue RNA - liver [nTPM]":"78.8","Tissue RNA - lung [nTPM]":"31.0","Tissue RNA - lymph node [nTPM]":"12.3","Tissue RNA - medulla oblongata [nTPM]":"32.4","Tissue RNA - midbrain [nTPM]":"27.8","Tissue RNA - ovary [nTPM]":"19.6","Tissue RNA - pancreas [nTPM]":"25.3","Tissue RNA - parathyroid gland [nTPM]":"8.3","Tissue RNA - pituitary gland [nTPM]":"18.9","Tissue RNA - placenta [nTPM]":"6.3","Tissue RNA - pons [nTPM]":"39.3","Tissue RNA - prostate [nTPM]":"23.5","Tissue RNA - rectum [nTPM]":"4.2","Tissue RNA - retina [nTPM]":"3.4","Tissue RNA - salivary gland [nTPM]":"25.1","Tissue RNA - seminal vesicle [nTPM]":"6.5","Tissue RNA - skeletal muscle [nTPM]":"27.2","Tissue RNA - skin 1 [nTPM]":"52.3","Tissue RNA - small intestine [nTPM]":"26.6","Tissue RNA - smooth muscle [nTPM]":"5.7","Tissue RNA - spinal cord [nTPM]":"24.0","Tissue RNA - spleen [nTPM]":"24.6","Tissue RNA - stomach 1 [nTPM]":"31.5","Tissue RNA - testis [nTPM]":"42.3","Tissue RNA - thalamus [nTPM]":"24.7","Tissue RNA - thymus [nTPM]":"7.0","Tissue RNA - thyroid gland [nTPM]":"21.1","Tissue RNA - tongue [nTPM]":"8.3","Tissue RNA - tonsil [nTPM]":"6.8","Tissue RNA - urinary bladder [nTPM]":"17.6","Tissue RNA - vagina [nTPM]":"36.9","Tissue RNA - white matter [nTPM]":"25.6","Cell RNA - A-431 [nTPM]":"50.6","Cell RNA - A549 [nTPM]":"34.2","Cell RNA - AF22 [nTPM]":"52.4","Cell RNA - AN3-CA [nTPM]":"33.1","Cell RNA - ASC diff [nTPM]":"18.1","Cell RNA - ASC TERT1 [nTPM]":"38.7","Cell RNA - BEWO [nTPM]":"29.5","Cell RNA - BJ [nTPM]":"25.1","Cell RNA - BJ hTERT+ [nTPM]":"26.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.6","Cell RNA - CACO-2 [nTPM]":"86.1","Cell RNA - CAPAN-2 [nTPM]":"119.7","Cell RNA - Daudi [nTPM]":"24.4","Cell RNA - EFO-21 [nTPM]":"39.8","Cell RNA - fHDF\/TERT166 [nTPM]":"15.7","Cell RNA - GAMG [nTPM]":"63.7","Cell RNA - HaCaT [nTPM]":"72.8","Cell RNA - HAP1 [nTPM]":"25.0","Cell RNA - HBEC3-KT [nTPM]":"133.1","Cell RNA - HBF TERT88 [nTPM]":"4.9","Cell RNA - HDLM-2 [nTPM]":"15.7","Cell RNA - HEK 293 [nTPM]":"38.3","Cell RNA - HEL [nTPM]":"17.8","Cell RNA - HeLa [nTPM]":"18.2","Cell RNA - Hep G2 [nTPM]":"127.0","Cell RNA - HHSteC [nTPM]":"35.9","Cell RNA - HL-60 [nTPM]":"11.6","Cell RNA - HMC-1 [nTPM]":"11.8","Cell RNA - HSkMC [nTPM]":"30.9","Cell RNA - hTCEpi [nTPM]":"24.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"46.6","Cell RNA - hTERT-HME1 [nTPM]":"13.5","Cell RNA - hTERT-RPE1 [nTPM]":"8.7","Cell RNA - HUVEC TERT2 [nTPM]":"18.0","Cell RNA - JURKAT [nTPM]":"58.0","Cell RNA - K-562 [nTPM]":"51.7","Cell RNA - Karpas-707 [nTPM]":"13.1","Cell RNA - LHCN-M2 [nTPM]":"10.2","Cell RNA - MCF7 [nTPM]":"115.9","Cell RNA - MOLT-4 [nTPM]":"39.3","Cell RNA - NB-4 [nTPM]":"56.6","Cell RNA - NTERA-2 [nTPM]":"61.5","Cell RNA - OE19 [nTPM]":"17.7","Cell RNA - PC-3 [nTPM]":"31.3","Cell RNA - REH [nTPM]":"40.2","Cell RNA - RH-30 [nTPM]":"15.0","Cell RNA - RPMI-8226 [nTPM]":"62.3","Cell RNA - RPTEC TERT1 [nTPM]":"49.8","Cell RNA - RT4 [nTPM]":"33.0","Cell RNA - SCLC-21H [nTPM]":"52.2","Cell RNA - SH-SY5Y [nTPM]":"17.9","Cell RNA - SiHa [nTPM]":"62.0","Cell RNA - SK-BR-3 [nTPM]":"13.3","Cell RNA - SK-MEL-30 [nTPM]":"18.5","Cell RNA - SuSa [nTPM]":"11.4","Cell RNA - T-47d [nTPM]":"67.8","Cell RNA - THP-1 [nTPM]":"51.3","Cell RNA - TIME [nTPM]":"39.0","Cell RNA - U-138 MG [nTPM]":"14.7","Cell RNA - U-2 OS [nTPM]":"29.8","Cell RNA - U-2197 [nTPM]":"27.2","Cell RNA - U-251 MG [nTPM]":"14.2","Cell RNA - U-266\/70 [nTPM]":"34.9","Cell RNA - U-266\/84 [nTPM]":"17.6","Cell RNA - U-698 [nTPM]":"83.2","Cell RNA - U-87 MG [nTPM]":"17.9","Cell RNA - U-937 [nTPM]":"55.7","Cell RNA - WM-115 [nTPM]":"25.7","Blood RNA - basophil [nTPM]":"5.6","Blood RNA - classical monocyte [nTPM]":"12.6","Blood RNA - eosinophil [nTPM]":"2.4","Blood RNA - gdT-cell [nTPM]":"26.8","Blood RNA - intermediate monocyte [nTPM]":"13.7","Blood RNA - MAIT T-cell [nTPM]":"20.4","Blood RNA - memory B-cell [nTPM]":"16.1","Blood RNA - memory CD4 T-cell [nTPM]":"18.0","Blood RNA - memory CD8 T-cell [nTPM]":"17.9","Blood RNA - myeloid DC [nTPM]":"15.0","Blood RNA - naive B-cell [nTPM]":"22.6","Blood RNA - naive CD4 T-cell [nTPM]":"13.2","Blood RNA - naive CD8 T-cell [nTPM]":"16.6","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"28.3","Blood RNA - non-classical monocyte [nTPM]":"15.4","Blood RNA - plasmacytoid DC [nTPM]":"28.0","Blood RNA - T-reg [nTPM]":"20.4","Blood RNA - total PBMC [nTPM]":"15.4","Brain RNA - amygdala [nTPM]":"24.2","Brain RNA - basal ganglia [nTPM]":"27.5","Brain RNA - cerebellum [nTPM]":"26.2","Brain RNA - cerebral cortex [nTPM]":"37.5","Brain RNA - hippocampal formation [nTPM]":"24.7","Brain RNA - hypothalamus [nTPM]":"27.8","Brain RNA - medulla oblongata [nTPM]":"32.4","Brain RNA - midbrain [nTPM]":"27.8","Brain RNA - pons [nTPM]":"39.3","Brain RNA - spinal cord [nTPM]":"24.0","Brain RNA - thalamus [nTPM]":"24.7","Brain RNA - white matter [nTPM]":"25.6","Single Cell Type RNA - Adipocytes [nTPM]":"17.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"48.2","Single Cell Type RNA - Astrocytes [nTPM]":"22.2","Single Cell Type RNA - B-cells [nTPM]":"21.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"106.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"27.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"56.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.2","Single Cell Type RNA - dendritic cells [nTPM]":"79.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"117.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"25.4","Single Cell Type RNA - Ductal cells [nTPM]":"30.8","Single Cell Type RNA - Early spermatids [nTPM]":"61.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.0","Single Cell Type RNA - Endothelial cells [nTPM]":"15.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"32.9","Single Cell Type RNA - Erythroid cells [nTPM]":"26.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"62.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"29.2","Single Cell Type RNA - Fibroblasts [nTPM]":"15.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"41.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.5","Single Cell Type RNA - granulocytes [nTPM]":"16.5","Single Cell Type RNA - Granulosa cells [nTPM]":"27.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.7","Single Cell Type RNA - Hepatocytes [nTPM]":"147.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"38.6","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"75.3","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"25.5","Single Cell Type RNA - Langerhans cells [nTPM]":"21.6","Single Cell Type RNA - Late spermatids [nTPM]":"96.2","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"20.3","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"32.2","Single Cell Type RNA - Muller glia cells [nTPM]":"16.5","Single Cell Type RNA - NK-cells [nTPM]":"55.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"30.0","Single Cell Type RNA - Paneth cells [nTPM]":"79.4","Single Cell Type RNA - Peritubular cells [nTPM]":"9.1","Single Cell Type RNA - Plasma cells [nTPM]":"46.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"47.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.7","Single Cell Type RNA - Spermatocytes [nTPM]":"50.8","Single Cell Type RNA - Spermatogonia [nTPM]":"13.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"48.8","Single Cell Type RNA - T-cells [nTPM]":"36.3","Single Cell Type RNA - Theca cells [nTPM]":"35.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"65.2","Single Cell Type RNA - Urothelial cells [nTPM]":"20.6"},{"Gene":"MVK","Gene synonym":["LRBP","MK"],"Ensembl":"ENSG00000110921","Gene description":"Mevalonate kinase","Uniprot":["Q03426"],"Chromosome":"12","Position":"109573255-109598125","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"69.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"60.5","Horizontal cells":"62.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016961","HPA044110"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA016961":"AB_1854220","HPA044110":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.9","Tissue RNA - adrenal gland [nTPM]":"29.8","Tissue RNA - amygdala [nTPM]":"12.7","Tissue RNA - appendix [nTPM]":"6.1","Tissue RNA - basal ganglia [nTPM]":"13.7","Tissue RNA - bone marrow [nTPM]":"8.3","Tissue RNA - breast [nTPM]":"14.7","Tissue RNA - cerebellum [nTPM]":"16.7","Tissue RNA - cerebral cortex [nTPM]":"15.0","Tissue RNA - cervix [nTPM]":"14.5","Tissue RNA - choroid plexus [nTPM]":"9.6","Tissue RNA - colon [nTPM]":"11.2","Tissue RNA - duodenum [nTPM]":"13.9","Tissue RNA - endometrium 1 [nTPM]":"7.3","Tissue RNA - epididymis [nTPM]":"10.2","Tissue RNA - esophagus [nTPM]":"45.5","Tissue RNA - fallopian tube [nTPM]":"6.3","Tissue RNA - gallbladder [nTPM]":"5.3","Tissue RNA - heart muscle [nTPM]":"9.4","Tissue RNA - hippocampal formation [nTPM]":"11.1","Tissue RNA - hypothalamus [nTPM]":"13.2","Tissue RNA - kidney [nTPM]":"32.1","Tissue RNA - liver [nTPM]":"69.1","Tissue RNA - lung [nTPM]":"11.4","Tissue RNA - lymph node [nTPM]":"6.9","Tissue RNA - medulla oblongata [nTPM]":"36.1","Tissue RNA - midbrain [nTPM]":"15.5","Tissue RNA - ovary [nTPM]":"10.7","Tissue RNA - pancreas [nTPM]":"10.0","Tissue RNA - parathyroid gland [nTPM]":"11.5","Tissue RNA - pituitary gland [nTPM]":"11.6","Tissue RNA - placenta [nTPM]":"5.4","Tissue RNA - pons [nTPM]":"38.6","Tissue RNA - prostate [nTPM]":"12.3","Tissue RNA - rectum [nTPM]":"8.6","Tissue RNA - retina [nTPM]":"7.3","Tissue RNA - salivary gland [nTPM]":"13.7","Tissue RNA - seminal vesicle [nTPM]":"7.0","Tissue RNA - skeletal muscle [nTPM]":"12.1","Tissue RNA - skin 1 [nTPM]":"33.3","Tissue RNA - small intestine [nTPM]":"9.8","Tissue RNA - smooth muscle [nTPM]":"5.0","Tissue RNA - spinal cord [nTPM]":"15.3","Tissue RNA - spleen [nTPM]":"6.7","Tissue RNA - stomach 1 [nTPM]":"11.8","Tissue RNA - testis [nTPM]":"28.5","Tissue RNA - thalamus [nTPM]":"15.3","Tissue RNA - thymus [nTPM]":"4.2","Tissue RNA - thyroid gland [nTPM]":"15.1","Tissue RNA - tongue [nTPM]":"8.8","Tissue RNA - tonsil [nTPM]":"9.1","Tissue RNA - urinary bladder [nTPM]":"9.5","Tissue RNA - vagina [nTPM]":"20.1","Tissue RNA - white matter [nTPM]":"24.4","Cell RNA - A-431 [nTPM]":"30.1","Cell RNA - A549 [nTPM]":"25.0","Cell RNA - AF22 [nTPM]":"29.9","Cell RNA - AN3-CA [nTPM]":"13.7","Cell RNA - ASC diff [nTPM]":"11.2","Cell RNA - ASC TERT1 [nTPM]":"27.3","Cell RNA - BEWO [nTPM]":"14.4","Cell RNA - BJ [nTPM]":"9.5","Cell RNA - BJ hTERT+ [nTPM]":"21.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"30.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"32.8","Cell RNA - CACO-2 [nTPM]":"31.4","Cell RNA - CAPAN-2 [nTPM]":"33.8","Cell RNA - Daudi [nTPM]":"17.7","Cell RNA - EFO-21 [nTPM]":"7.8","Cell RNA - fHDF\/TERT166 [nTPM]":"11.7","Cell RNA - GAMG [nTPM]":"48.1","Cell RNA - HaCaT [nTPM]":"36.0","Cell RNA - HAP1 [nTPM]":"31.6","Cell RNA - HBEC3-KT [nTPM]":"50.0","Cell RNA - HBF TERT88 [nTPM]":"13.2","Cell RNA - HDLM-2 [nTPM]":"19.0","Cell RNA - HEK 293 [nTPM]":"18.1","Cell RNA - HEL [nTPM]":"9.9","Cell RNA - HeLa [nTPM]":"15.7","Cell RNA - Hep G2 [nTPM]":"53.7","Cell RNA - HHSteC [nTPM]":"31.5","Cell RNA - HL-60 [nTPM]":"11.1","Cell RNA - HMC-1 [nTPM]":"13.0","Cell RNA - HSkMC [nTPM]":"27.2","Cell RNA - hTCEpi [nTPM]":"42.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"48.8","Cell RNA - hTERT-HME1 [nTPM]":"13.6","Cell RNA - hTERT-RPE1 [nTPM]":"12.6","Cell RNA - HUVEC TERT2 [nTPM]":"20.9","Cell RNA - JURKAT [nTPM]":"19.0","Cell RNA - K-562 [nTPM]":"18.7","Cell RNA - Karpas-707 [nTPM]":"17.4","Cell RNA - LHCN-M2 [nTPM]":"13.6","Cell RNA - MCF7 [nTPM]":"34.5","Cell RNA - MOLT-4 [nTPM]":"12.0","Cell RNA - NB-4 [nTPM]":"34.6","Cell RNA - NTERA-2 [nTPM]":"22.6","Cell RNA - OE19 [nTPM]":"14.9","Cell RNA - PC-3 [nTPM]":"32.3","Cell RNA - REH [nTPM]":"10.5","Cell RNA - RH-30 [nTPM]":"22.1","Cell RNA - RPMI-8226 [nTPM]":"37.0","Cell RNA - RPTEC TERT1 [nTPM]":"67.4","Cell RNA - RT4 [nTPM]":"40.9","Cell RNA - SCLC-21H [nTPM]":"25.1","Cell RNA - SH-SY5Y [nTPM]":"18.7","Cell RNA - SiHa [nTPM]":"19.8","Cell RNA - SK-BR-3 [nTPM]":"58.7","Cell RNA - SK-MEL-30 [nTPM]":"14.0","Cell RNA - SuSa [nTPM]":"11.0","Cell RNA - T-47d [nTPM]":"59.7","Cell RNA - THP-1 [nTPM]":"21.1","Cell RNA - TIME [nTPM]":"14.1","Cell RNA - U-138 MG [nTPM]":"13.2","Cell RNA - U-2 OS [nTPM]":"14.5","Cell RNA - U-2197 [nTPM]":"12.0","Cell RNA - U-251 MG [nTPM]":"12.8","Cell RNA - U-266\/70 [nTPM]":"13.3","Cell RNA - U-266\/84 [nTPM]":"20.6","Cell RNA - U-698 [nTPM]":"28.2","Cell RNA - U-87 MG [nTPM]":"16.1","Cell RNA - U-937 [nTPM]":"29.2","Cell RNA - WM-115 [nTPM]":"16.6","Blood RNA - basophil [nTPM]":"1.0","Blood RNA - classical monocyte [nTPM]":"6.9","Blood RNA - eosinophil [nTPM]":"4.0","Blood RNA - gdT-cell [nTPM]":"12.6","Blood RNA - intermediate monocyte [nTPM]":"6.5","Blood RNA - MAIT T-cell [nTPM]":"11.3","Blood RNA - memory B-cell [nTPM]":"9.4","Blood RNA - memory CD4 T-cell [nTPM]":"7.4","Blood RNA - memory CD8 T-cell [nTPM]":"12.4","Blood RNA - myeloid DC [nTPM]":"8.6","Blood RNA - naive B-cell [nTPM]":"14.1","Blood RNA - naive CD4 T-cell [nTPM]":"10.9","Blood RNA - naive CD8 T-cell [nTPM]":"8.3","Blood RNA - neutrophil [nTPM]":"1.6","Blood RNA - NK-cell [nTPM]":"11.0","Blood RNA - non-classical monocyte [nTPM]":"4.6","Blood RNA - plasmacytoid DC [nTPM]":"7.0","Blood RNA - T-reg [nTPM]":"7.6","Blood RNA - total PBMC [nTPM]":"6.4","Brain RNA - amygdala [nTPM]":"12.7","Brain RNA - basal ganglia [nTPM]":"13.7","Brain RNA - cerebellum [nTPM]":"16.7","Brain RNA - cerebral cortex [nTPM]":"15.0","Brain RNA - hippocampal formation [nTPM]":"11.1","Brain RNA - hypothalamus [nTPM]":"13.2","Brain RNA - medulla oblongata [nTPM]":"36.1","Brain RNA - midbrain [nTPM]":"15.5","Brain RNA - pons [nTPM]":"38.6","Brain RNA - spinal cord [nTPM]":"15.3","Brain RNA - thalamus [nTPM]":"15.3","Brain RNA - white matter [nTPM]":"24.4","Single Cell Type RNA - Adipocytes [nTPM]":"6.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.4","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"8.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"39.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"12.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"25.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"33.0","Single Cell Type RNA - dendritic cells [nTPM]":"7.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"15.6","Single Cell Type RNA - Early spermatids [nTPM]":"60.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.3","Single Cell Type RNA - Endothelial cells [nTPM]":"7.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.0","Single Cell Type RNA - Erythroid cells [nTPM]":"4.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.3","Single Cell Type RNA - Fibroblasts [nTPM]":"6.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"14.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"32.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.6","Single Cell Type RNA - Horizontal cells [nTPM]":"62.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.8","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"3.4","Single Cell Type RNA - Langerhans cells [nTPM]":"2.2","Single Cell Type RNA - Late spermatids [nTPM]":"42.5","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"4.8","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"10.3","Single Cell Type RNA - Muller glia cells [nTPM]":"10.6","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.2","Single Cell Type RNA - Paneth cells [nTPM]":"3.2","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"4.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"16.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"52.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.2","Single Cell Type RNA - Spermatocytes [nTPM]":"33.9","Single Cell Type RNA - Spermatogonia [nTPM]":"16.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"47.9","Single Cell Type RNA - T-cells [nTPM]":"6.1","Single Cell Type RNA - Theca cells [nTPM]":"44.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.1","Single Cell Type RNA - Urothelial cells [nTPM]":"4.6"},{"Gene":"MYLK","Gene synonym":["MLCK","MLCK1","MYLK1","smMLCK"],"Ensembl":"ENSG00000065534","Gene description":"Myosin light chain kinase","Uniprot":["Q15746"],"Chromosome":"3","Position":"123610049-123884332","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Actin-binding","Calmodulin-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Aortic aneurysm","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"seminal vesicle":"1700.3","smooth muscle":"2137.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast myoepithelial cells":"728.5","Hepatocytes":"208.7","Peritubular cells":"690.5","Sertoli cells":"276.1","Smooth muscle cells":"448.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"7.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ":"200.0","BJ hTERT+":"298.2","fHDF\/TERT166":"260.2","hTERT-RPE1":"202.7","RPTEC TERT1":"291.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB020789","HPA031677","HPA048055"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane","Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1500000","Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":["Actin filaments"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB020789":null,"HPA031677":"AB_10794617","HPA048055":"AB_2732543"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.04e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.46e-4"},"Tissue RNA - adipose tissue [nTPM]":"143.6","Tissue RNA - adrenal gland [nTPM]":"57.4","Tissue RNA - amygdala [nTPM]":"37.6","Tissue RNA - appendix [nTPM]":"188.7","Tissue RNA - basal ganglia [nTPM]":"64.8","Tissue RNA - bone marrow [nTPM]":"3.3","Tissue RNA - breast [nTPM]":"163.4","Tissue RNA - cerebellum [nTPM]":"72.1","Tissue RNA - cerebral cortex [nTPM]":"42.4","Tissue RNA - cervix [nTPM]":"281.3","Tissue RNA - choroid plexus [nTPM]":"14.1","Tissue RNA - colon [nTPM]":"551.5","Tissue RNA - duodenum [nTPM]":"110.9","Tissue RNA - endometrium 1 [nTPM]":"669.2","Tissue RNA - epididymis [nTPM]":"232.9","Tissue RNA - esophagus [nTPM]":"420.6","Tissue RNA - fallopian tube [nTPM]":"289.8","Tissue RNA - gallbladder [nTPM]":"250.4","Tissue RNA - heart muscle [nTPM]":"33.6","Tissue RNA - hippocampal formation [nTPM]":"33.6","Tissue RNA - hypothalamus [nTPM]":"46.7","Tissue RNA - kidney [nTPM]":"64.4","Tissue RNA - liver [nTPM]":"67.2","Tissue RNA - lung [nTPM]":"85.2","Tissue RNA - lymph node [nTPM]":"33.6","Tissue RNA - medulla oblongata [nTPM]":"104.6","Tissue RNA - midbrain [nTPM]":"64.8","Tissue RNA - ovary [nTPM]":"95.9","Tissue RNA - pancreas [nTPM]":"15.3","Tissue RNA - parathyroid gland [nTPM]":"11.6","Tissue RNA - pituitary gland [nTPM]":"2.6","Tissue RNA - placenta [nTPM]":"70.2","Tissue RNA - pons [nTPM]":"99.3","Tissue RNA - prostate [nTPM]":"907.6","Tissue RNA - rectum [nTPM]":"299.1","Tissue RNA - retina [nTPM]":"13.6","Tissue RNA - salivary gland [nTPM]":"140.1","Tissue RNA - seminal vesicle [nTPM]":"1700.3","Tissue RNA - skeletal muscle [nTPM]":"10.0","Tissue RNA - skin 1 [nTPM]":"20.1","Tissue RNA - small intestine [nTPM]":"125.1","Tissue RNA - smooth muscle [nTPM]":"2137.7","Tissue RNA - spinal cord [nTPM]":"55.6","Tissue RNA - spleen [nTPM]":"89.5","Tissue RNA - stomach 1 [nTPM]":"122.7","Tissue RNA - testis [nTPM]":"50.5","Tissue RNA - thalamus [nTPM]":"52.2","Tissue RNA - thymus [nTPM]":"8.0","Tissue RNA - thyroid gland [nTPM]":"22.2","Tissue RNA - tongue [nTPM]":"14.9","Tissue RNA - tonsil [nTPM]":"19.1","Tissue RNA - urinary bladder [nTPM]":"505.7","Tissue RNA - vagina [nTPM]":"84.8","Tissue RNA - white matter [nTPM]":"112.1","Cell RNA - A-431 [nTPM]":"14.4","Cell RNA - A549 [nTPM]":"38.4","Cell RNA - AF22 [nTPM]":"10.8","Cell RNA - AN3-CA [nTPM]":"7.8","Cell RNA - ASC diff [nTPM]":"10.8","Cell RNA - ASC TERT1 [nTPM]":"1.9","Cell RNA - BEWO [nTPM]":"4.7","Cell RNA - BJ [nTPM]":"200.0","Cell RNA - BJ hTERT+ [nTPM]":"298.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"137.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"92.1","Cell RNA - CACO-2 [nTPM]":"8.1","Cell RNA - CAPAN-2 [nTPM]":"7.4","Cell RNA - Daudi [nTPM]":"0.6","Cell RNA - EFO-21 [nTPM]":"42.5","Cell RNA - fHDF\/TERT166 [nTPM]":"260.2","Cell RNA - GAMG [nTPM]":"67.0","Cell RNA - HaCaT [nTPM]":"4.8","Cell RNA - HAP1 [nTPM]":"5.2","Cell RNA - HBEC3-KT [nTPM]":"1.8","Cell RNA - HBF TERT88 [nTPM]":"149.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.7","Cell RNA - HEL [nTPM]":"102.4","Cell RNA - HeLa [nTPM]":"0.9","Cell RNA - Hep G2 [nTPM]":"28.9","Cell RNA - HHSteC [nTPM]":"56.1","Cell RNA - HL-60 [nTPM]":"0.6","Cell RNA - HMC-1 [nTPM]":"9.8","Cell RNA - HSkMC [nTPM]":"36.9","Cell RNA - hTCEpi [nTPM]":"3.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"24.4","Cell RNA - hTERT-HME1 [nTPM]":"34.4","Cell RNA - hTERT-RPE1 [nTPM]":"202.7","Cell RNA - HUVEC TERT2 [nTPM]":"8.9","Cell RNA - JURKAT [nTPM]":"1.3","Cell RNA - K-562 [nTPM]":"1.2","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"90.9","Cell RNA - MCF7 [nTPM]":"1.7","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"2.5","Cell RNA - NTERA-2 [nTPM]":"12.0","Cell RNA - OE19 [nTPM]":"0.5","Cell RNA - PC-3 [nTPM]":"5.1","Cell RNA - REH [nTPM]":"13.5","Cell RNA - RH-30 [nTPM]":"6.8","Cell RNA - RPMI-8226 [nTPM]":"36.7","Cell RNA - RPTEC TERT1 [nTPM]":"291.9","Cell RNA - RT4 [nTPM]":"8.5","Cell RNA - SCLC-21H [nTPM]":"1.4","Cell RNA - SH-SY5Y [nTPM]":"6.4","Cell RNA - SiHa [nTPM]":"21.8","Cell RNA - SK-BR-3 [nTPM]":"1.9","Cell RNA - SK-MEL-30 [nTPM]":"3.1","Cell RNA - SuSa [nTPM]":"25.0","Cell RNA - T-47d [nTPM]":"1.0","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"33.4","Cell RNA - U-138 MG [nTPM]":"39.5","Cell RNA - U-2 OS [nTPM]":"13.9","Cell RNA - U-2197 [nTPM]":"10.3","Cell RNA - U-251 MG [nTPM]":"30.7","Cell RNA - U-266\/70 [nTPM]":"3.4","Cell RNA - U-266\/84 [nTPM]":"4.2","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"104.0","Cell RNA - U-937 [nTPM]":"1.0","Cell RNA - WM-115 [nTPM]":"9.6","Blood RNA - basophil [nTPM]":"7.4","Blood RNA - classical monocyte [nTPM]":"1.6","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"3.5","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"5.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"3.3","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"20.9","Brain RNA - amygdala [nTPM]":"37.6","Brain RNA - basal ganglia [nTPM]":"64.8","Brain RNA - cerebellum [nTPM]":"72.1","Brain RNA - cerebral cortex [nTPM]":"42.4","Brain RNA - hippocampal formation [nTPM]":"33.6","Brain RNA - hypothalamus [nTPM]":"46.7","Brain RNA - medulla oblongata [nTPM]":"104.6","Brain RNA - midbrain [nTPM]":"64.8","Brain RNA - pons [nTPM]":"99.3","Brain RNA - spinal cord [nTPM]":"55.6","Brain RNA - thalamus [nTPM]":"52.2","Brain RNA - white matter [nTPM]":"112.1","Single Cell Type RNA - Adipocytes [nTPM]":"45.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"38.3","Single Cell Type RNA - Astrocytes [nTPM]":"43.4","Single Cell Type RNA - B-cells [nTPM]":"2.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"24.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"2.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"728.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"37.1","Single Cell Type RNA - Club cells [nTPM]":"5.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"125.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - dendritic cells [nTPM]":"3.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"88.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.0","Single Cell Type RNA - Early spermatids [nTPM]":"40.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"45.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"46.6","Single Cell Type RNA - Endothelial cells [nTPM]":"56.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.4","Single Cell Type RNA - Erythroid cells [nTPM]":"3.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.8","Single Cell Type RNA - Fibroblasts [nTPM]":"40.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"54.4","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"3.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"45.3","Single Cell Type RNA - Hepatocytes [nTPM]":"208.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.9","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.9","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"7.9","Single Cell Type RNA - Langerhans cells [nTPM]":"37.0","Single Cell Type RNA - Late spermatids [nTPM]":"33.8","Single Cell Type RNA - Leydig cells [nTPM]":"104.7","Single Cell Type RNA - Macrophages [nTPM]":"20.8","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"1.2","Single Cell Type RNA - Muller glia cells [nTPM]":"4.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"37.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.0","Single Cell Type RNA - Paneth cells [nTPM]":"18.7","Single Cell Type RNA - Peritubular cells [nTPM]":"690.5","Single Cell Type RNA - Plasma cells [nTPM]":"3.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.9","Single Cell Type RNA - Sertoli cells [nTPM]":"276.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"448.7","Single Cell Type RNA - Spermatocytes [nTPM]":"4.7","Single Cell Type RNA - Spermatogonia [nTPM]":"4.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - T-cells [nTPM]":"3.2","Single Cell Type RNA - Theca cells [nTPM]":"4.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.2","Single Cell Type RNA - Urothelial cells [nTPM]":"3.7"},{"Gene":"MYLK2","Gene synonym":["KMLC","MLCK2","skMLCK"],"Ensembl":"ENSG00000101306","Gene description":"Myosin light chain kinase 2","Uniprot":["Q9H1R3"],"Chromosome":"20","Position":"31819308-31834689","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Calmodulin-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cardiomyopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"skeletal muscle":"732.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Skeletal myocytes":"15.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"4.1","RH-30":"10.5","RPMI-8226":"8.8"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059704","HPA059890"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 37: Myocytes - Muscle contraction","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA059704":"AB_2684108","HPA059890":"AB_2684153"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.00e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.6","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"0.7","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.5","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"4.7","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"0.6","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.6","Tissue RNA - midbrain [nTPM]":"0.7","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"5.5","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.7","Tissue RNA - prostate [nTPM]":"1.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"2.4","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"732.0","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.7","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"60.3","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.7","Cell RNA - AN3-CA [nTPM]":"0.6","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.3","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"1.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.8","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"4.1","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.6","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.6","Cell RNA - RH-30 [nTPM]":"10.5","Cell RNA - RPMI-8226 [nTPM]":"8.8","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"2.7","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"2.1","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"2.4","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.8","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"2.5","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.6","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"0.7","Brain RNA - hippocampal formation [nTPM]":"0.6","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"0.6","Brain RNA - midbrain [nTPM]":"0.7","Brain RNA - pons [nTPM]":"0.7","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"0.7","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"MYMK","Gene synonym":["TMEM226","TMEM8C"],"Ensembl":"ENSG00000187616","Gene description":"Myomaker, myoblast fusion factor","Uniprot":["A6NI61"],"Chromosome":"9","Position":"133514586-133528612","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Myogenesis"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.1"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"32","RNA cell line specific nTPM":{"HSkMC":"15.2","RH-30":"7.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051846","HPA055785"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051846":"AB_2681636","HPA055785":"AB_2682920"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"1.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.5","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.6","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"1.1","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"15.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"7.0","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"1.1","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.5","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"1.1","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"MYO3A","Gene synonym":["DFNB30"],"Ensembl":"ENSG00000095777","Gene description":"Myosin IIIA","Uniprot":["Q8NEV4"],"Chromosome":"10","Position":"25934229-26212532","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Hearing","Sensory transduction","Vision"],"Molecular function":["Actin-binding","Kinase","Motor protein","Myosin","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"retina":"15.5","testis":"5.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"156.6","Late spermatids":"58.2","Muller glia cells":"74.8","Spermatocytes":"31.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"cervical cancer":"1.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"1.3","CAPAN-2":"1.2","HEK 293":"1.5","SCLC-21H":"1.4","U-2 OS":"2.4","U-698":"6.3"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051893","HPA075413"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Actin filaments","Cytoplasmic bodies"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 5: Muller glia cells - Visual perception","Subcellular main location":["Actin filaments","Cytoplasmic bodies"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA051893":null,"HPA075413":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"1.8","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.8","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.6","Tissue RNA - midbrain [nTPM]":"0.5","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.7","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.5","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"15.5","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"5.2","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"1.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"1.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.5","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.9","Cell RNA - OE19 [nTPM]":"0.8","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.7","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.4","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.7","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"2.4","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"6.3","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"1.8","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.8","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"0.6","Brain RNA - midbrain [nTPM]":"0.5","Brain RNA - pons [nTPM]":"0.5","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"156.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"58.2","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"74.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.4","Single Cell Type RNA - Spermatocytes [nTPM]":"31.7","Single Cell Type RNA - Spermatogonia [nTPM]":"14.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"MYSM1","Gene synonym":["KIAA1915"],"Ensembl":"ENSG00000162601","Gene description":"Myb like, SWIRM and MPN domains 1","Uniprot":["Q5VVJ2"],"Chromosome":"1","Position":"58643440-58700077","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Immunity","Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["Activator","Chromatin regulator","DNA-binding","Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"106.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054291","HPA057306"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA054291":"AB_2682438","HPA057306":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.09e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.63e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.2","Tissue RNA - adrenal gland [nTPM]":"7.5","Tissue RNA - amygdala [nTPM]":"4.0","Tissue RNA - appendix [nTPM]":"4.4","Tissue RNA - basal ganglia [nTPM]":"3.9","Tissue RNA - bone marrow [nTPM]":"12.5","Tissue RNA - breast [nTPM]":"12.0","Tissue RNA - cerebellum [nTPM]":"4.3","Tissue RNA - cerebral cortex [nTPM]":"5.9","Tissue RNA - cervix [nTPM]":"11.9","Tissue RNA - choroid plexus [nTPM]":"4.2","Tissue RNA - colon [nTPM]":"11.8","Tissue RNA - duodenum [nTPM]":"5.4","Tissue RNA - endometrium 1 [nTPM]":"10.6","Tissue RNA - epididymis [nTPM]":"6.2","Tissue RNA - esophagus [nTPM]":"10.0","Tissue RNA - fallopian tube [nTPM]":"10.2","Tissue RNA - gallbladder [nTPM]":"3.1","Tissue RNA - heart muscle [nTPM]":"10.5","Tissue RNA - hippocampal formation [nTPM]":"4.1","Tissue RNA - hypothalamus [nTPM]":"3.9","Tissue RNA - kidney [nTPM]":"7.2","Tissue RNA - liver [nTPM]":"8.0","Tissue RNA - lung [nTPM]":"10.1","Tissue RNA - lymph node [nTPM]":"6.3","Tissue RNA - medulla oblongata [nTPM]":"3.9","Tissue RNA - midbrain [nTPM]":"3.7","Tissue RNA - ovary [nTPM]":"13.2","Tissue RNA - pancreas [nTPM]":"12.1","Tissue RNA - parathyroid gland [nTPM]":"5.9","Tissue RNA - pituitary gland [nTPM]":"8.7","Tissue RNA - placenta [nTPM]":"4.4","Tissue RNA - pons [nTPM]":"3.9","Tissue RNA - prostate [nTPM]":"9.6","Tissue RNA - rectum [nTPM]":"4.4","Tissue RNA - retina [nTPM]":"8.4","Tissue RNA - salivary gland [nTPM]":"11.8","Tissue RNA - seminal vesicle [nTPM]":"4.1","Tissue RNA - skeletal muscle [nTPM]":"10.0","Tissue RNA - skin 1 [nTPM]":"10.5","Tissue RNA - small intestine [nTPM]":"12.6","Tissue RNA - smooth muscle [nTPM]":"3.6","Tissue RNA - spinal cord [nTPM]":"3.7","Tissue RNA - spleen [nTPM]":"11.4","Tissue RNA - stomach 1 [nTPM]":"9.9","Tissue RNA - testis [nTPM]":"4.4","Tissue RNA - thalamus [nTPM]":"3.9","Tissue RNA - thymus [nTPM]":"5.3","Tissue RNA - thyroid gland [nTPM]":"11.5","Tissue RNA - tongue [nTPM]":"3.1","Tissue RNA - tonsil [nTPM]":"4.9","Tissue RNA - urinary bladder [nTPM]":"9.3","Tissue RNA - vagina [nTPM]":"11.1","Tissue RNA - white matter [nTPM]":"4.4","Cell RNA - A-431 [nTPM]":"10.1","Cell RNA - A549 [nTPM]":"2.6","Cell RNA - AF22 [nTPM]":"5.0","Cell RNA - AN3-CA [nTPM]":"6.7","Cell RNA - ASC diff [nTPM]":"6.0","Cell RNA - ASC TERT1 [nTPM]":"7.2","Cell RNA - BEWO [nTPM]":"10.5","Cell RNA - BJ [nTPM]":"5.9","Cell RNA - BJ hTERT+ [nTPM]":"5.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.9","Cell RNA - CACO-2 [nTPM]":"5.3","Cell RNA - CAPAN-2 [nTPM]":"4.2","Cell RNA - Daudi [nTPM]":"10.3","Cell RNA - EFO-21 [nTPM]":"1.8","Cell RNA - fHDF\/TERT166 [nTPM]":"3.8","Cell RNA - GAMG [nTPM]":"4.8","Cell RNA - HaCaT [nTPM]":"7.4","Cell RNA - HAP1 [nTPM]":"7.7","Cell RNA - HBEC3-KT [nTPM]":"2.1","Cell RNA - HBF TERT88 [nTPM]":"11.0","Cell RNA - HDLM-2 [nTPM]":"6.2","Cell RNA - HEK 293 [nTPM]":"4.3","Cell RNA - HEL [nTPM]":"11.3","Cell RNA - HeLa [nTPM]":"2.1","Cell RNA - Hep G2 [nTPM]":"5.1","Cell RNA - HHSteC [nTPM]":"7.4","Cell RNA - HL-60 [nTPM]":"19.6","Cell RNA - HMC-1 [nTPM]":"9.7","Cell RNA - HSkMC [nTPM]":"5.4","Cell RNA - hTCEpi [nTPM]":"5.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.5","Cell RNA - hTERT-HME1 [nTPM]":"3.8","Cell RNA - hTERT-RPE1 [nTPM]":"6.1","Cell RNA - HUVEC TERT2 [nTPM]":"1.2","Cell RNA - JURKAT [nTPM]":"4.2","Cell RNA - K-562 [nTPM]":"12.6","Cell RNA - Karpas-707 [nTPM]":"6.3","Cell RNA - LHCN-M2 [nTPM]":"6.8","Cell RNA - MCF7 [nTPM]":"2.6","Cell RNA - MOLT-4 [nTPM]":"7.8","Cell RNA - NB-4 [nTPM]":"16.3","Cell RNA - NTERA-2 [nTPM]":"11.4","Cell RNA - OE19 [nTPM]":"3.5","Cell RNA - PC-3 [nTPM]":"3.5","Cell RNA - REH [nTPM]":"7.3","Cell RNA - RH-30 [nTPM]":"16.4","Cell RNA - RPMI-8226 [nTPM]":"6.1","Cell RNA - RPTEC TERT1 [nTPM]":"4.6","Cell RNA - RT4 [nTPM]":"3.8","Cell RNA - SCLC-21H [nTPM]":"5.8","Cell RNA - SH-SY5Y [nTPM]":"6.6","Cell RNA - SiHa [nTPM]":"4.4","Cell RNA - SK-BR-3 [nTPM]":"9.4","Cell RNA - SK-MEL-30 [nTPM]":"13.9","Cell RNA - SuSa [nTPM]":"9.0","Cell RNA - T-47d [nTPM]":"3.1","Cell RNA - THP-1 [nTPM]":"10.6","Cell RNA - TIME [nTPM]":"4.9","Cell RNA - U-138 MG [nTPM]":"9.3","Cell RNA - U-2 OS [nTPM]":"4.6","Cell RNA - U-2197 [nTPM]":"6.4","Cell RNA - U-251 MG [nTPM]":"11.3","Cell RNA - U-266\/70 [nTPM]":"10.8","Cell RNA - U-266\/84 [nTPM]":"5.8","Cell RNA - U-698 [nTPM]":"13.9","Cell RNA - U-87 MG [nTPM]":"5.8","Cell RNA - U-937 [nTPM]":"13.7","Cell RNA - WM-115 [nTPM]":"11.6","Blood RNA - basophil [nTPM]":"0.9","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"4.0","Brain RNA - basal ganglia [nTPM]":"3.9","Brain RNA - cerebellum [nTPM]":"4.3","Brain RNA - cerebral cortex [nTPM]":"5.9","Brain RNA - hippocampal formation [nTPM]":"4.1","Brain RNA - hypothalamus [nTPM]":"3.9","Brain RNA - medulla oblongata [nTPM]":"3.9","Brain RNA - midbrain [nTPM]":"3.7","Brain RNA - pons [nTPM]":"3.9","Brain RNA - spinal cord [nTPM]":"3.7","Brain RNA - thalamus [nTPM]":"3.9","Brain RNA - white matter [nTPM]":"4.4","Single Cell Type RNA - Adipocytes [nTPM]":"36.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"33.7","Single Cell Type RNA - Astrocytes [nTPM]":"47.7","Single Cell Type RNA - B-cells [nTPM]":"26.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"19.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"30.7","Single Cell Type RNA - Bipolar cells [nTPM]":"19.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"28.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"35.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.4","Single Cell Type RNA - dendritic cells [nTPM]":"36.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"22.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"8.8","Single Cell Type RNA - Early spermatids [nTPM]":"3.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"34.8","Single Cell Type RNA - Endothelial cells [nTPM]":"25.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.2","Single Cell Type RNA - Erythroid cells [nTPM]":"14.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"87.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.7","Single Cell Type RNA - Fibroblasts [nTPM]":"20.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"36.9","Single Cell Type RNA - granulocytes [nTPM]":"56.3","Single Cell Type RNA - Granulosa cells [nTPM]":"30.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.9","Single Cell Type RNA - Hepatocytes [nTPM]":"16.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.3","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"58.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.0","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"13.9","Single Cell Type RNA - Langerhans cells [nTPM]":"14.2","Single Cell Type RNA - Late spermatids [nTPM]":"6.3","Single Cell Type RNA - Leydig cells [nTPM]":"12.8","Single Cell Type RNA - Macrophages [nTPM]":"22.2","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"35.6","Single Cell Type RNA - monocytes [nTPM]":"21.3","Single Cell Type RNA - Muller glia cells [nTPM]":"12.7","Single Cell Type RNA - NK-cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"58.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"106.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.7","Single Cell Type RNA - Paneth cells [nTPM]":"13.1","Single Cell Type RNA - Peritubular cells [nTPM]":"17.3","Single Cell Type RNA - Plasma cells [nTPM]":"29.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"19.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"27.8","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"28.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.5","Single Cell Type RNA - Spermatocytes [nTPM]":"15.5","Single Cell Type RNA - Spermatogonia [nTPM]":"20.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.4","Single Cell Type RNA - T-cells [nTPM]":"30.8","Single Cell Type RNA - Theca cells [nTPM]":"22.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.5","Single Cell Type RNA - Urothelial cells [nTPM]":"26.4"},{"Gene":"NAA10","Gene synonym":["ARD1","ARD1A","DXS707","TE2"],"Ensembl":"ENSG00000102030","Gene description":"N-alpha-acetyltransferase 10, NatA catalytic subunit","Uniprot":["P41227"],"Chromosome":"X","Position":"153929225-153935080","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant","Microphthalmia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB006269","HPA030711"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"CAB006269":"AB_425759","HPA030711":"AB_2673579"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.29e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-3"},"Tissue RNA - adipose tissue [nTPM]":"38.4","Tissue RNA - adrenal gland [nTPM]":"39.5","Tissue RNA - amygdala [nTPM]":"19.6","Tissue RNA - appendix [nTPM]":"17.2","Tissue RNA - basal ganglia [nTPM]":"20.1","Tissue RNA - bone marrow [nTPM]":"13.2","Tissue RNA - breast [nTPM]":"34.6","Tissue RNA - cerebellum [nTPM]":"20.4","Tissue RNA - cerebral cortex [nTPM]":"27.2","Tissue RNA - cervix [nTPM]":"26.5","Tissue RNA - choroid plexus [nTPM]":"19.2","Tissue RNA - colon [nTPM]":"34.1","Tissue RNA - duodenum [nTPM]":"15.3","Tissue RNA - endometrium 1 [nTPM]":"32.3","Tissue RNA - epididymis [nTPM]":"15.1","Tissue RNA - esophagus [nTPM]":"40.5","Tissue RNA - fallopian tube [nTPM]":"24.4","Tissue RNA - gallbladder [nTPM]":"10.3","Tissue RNA - heart muscle [nTPM]":"56.3","Tissue RNA - hippocampal formation [nTPM]":"20.0","Tissue RNA - hypothalamus [nTPM]":"21.8","Tissue RNA - kidney [nTPM]":"34.1","Tissue RNA - liver [nTPM]":"35.9","Tissue RNA - lung [nTPM]":"26.0","Tissue RNA - lymph node [nTPM]":"19.7","Tissue RNA - medulla oblongata [nTPM]":"20.8","Tissue RNA - midbrain [nTPM]":"20.3","Tissue RNA - ovary [nTPM]":"23.8","Tissue RNA - pancreas [nTPM]":"45.8","Tissue RNA - parathyroid gland [nTPM]":"13.7","Tissue RNA - pituitary gland [nTPM]":"22.5","Tissue RNA - placenta [nTPM]":"12.5","Tissue RNA - pons [nTPM]":"20.8","Tissue RNA - prostate [nTPM]":"27.6","Tissue RNA - rectum [nTPM]":"10.2","Tissue RNA - retina [nTPM]":"7.3","Tissue RNA - salivary gland [nTPM]":"25.3","Tissue RNA - seminal vesicle [nTPM]":"12.2","Tissue RNA - skeletal muscle [nTPM]":"98.4","Tissue RNA - skin 1 [nTPM]":"30.9","Tissue RNA - small intestine [nTPM]":"24.9","Tissue RNA - smooth muscle [nTPM]":"18.1","Tissue RNA - spinal cord [nTPM]":"20.4","Tissue RNA - spleen [nTPM]":"28.8","Tissue RNA - stomach 1 [nTPM]":"35.9","Tissue RNA - testis [nTPM]":"9.1","Tissue RNA - thalamus [nTPM]":"21.2","Tissue RNA - thymus [nTPM]":"10.2","Tissue RNA - thyroid gland [nTPM]":"21.7","Tissue RNA - tongue [nTPM]":"24.9","Tissue RNA - tonsil [nTPM]":"15.3","Tissue RNA - urinary bladder [nTPM]":"35.9","Tissue RNA - vagina [nTPM]":"26.8","Tissue RNA - white matter [nTPM]":"20.4","Cell RNA - A-431 [nTPM]":"133.4","Cell RNA - A549 [nTPM]":"136.0","Cell RNA - AF22 [nTPM]":"25.8","Cell RNA - AN3-CA [nTPM]":"83.0","Cell RNA - ASC diff [nTPM]":"36.7","Cell RNA - ASC TERT1 [nTPM]":"36.9","Cell RNA - BEWO [nTPM]":"71.2","Cell RNA - BJ [nTPM]":"46.3","Cell RNA - BJ hTERT+ [nTPM]":"28.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"63.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"57.0","Cell RNA - CACO-2 [nTPM]":"88.5","Cell RNA - CAPAN-2 [nTPM]":"41.0","Cell RNA - Daudi [nTPM]":"102.0","Cell RNA - EFO-21 [nTPM]":"147.6","Cell RNA - fHDF\/TERT166 [nTPM]":"38.7","Cell RNA - GAMG [nTPM]":"79.2","Cell RNA - HaCaT [nTPM]":"63.0","Cell RNA - HAP1 [nTPM]":"57.9","Cell RNA - HBEC3-KT [nTPM]":"56.8","Cell RNA - HBF TERT88 [nTPM]":"23.9","Cell RNA - HDLM-2 [nTPM]":"42.1","Cell RNA - HEK 293 [nTPM]":"255.2","Cell RNA - HEL [nTPM]":"36.8","Cell RNA - HeLa [nTPM]":"85.8","Cell RNA - Hep G2 [nTPM]":"91.3","Cell RNA - HHSteC [nTPM]":"49.1","Cell RNA - HL-60 [nTPM]":"71.4","Cell RNA - HMC-1 [nTPM]":"76.8","Cell RNA - HSkMC [nTPM]":"28.8","Cell RNA - hTCEpi [nTPM]":"62.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"57.9","Cell RNA - hTERT-HME1 [nTPM]":"59.1","Cell RNA - hTERT-RPE1 [nTPM]":"30.7","Cell RNA - HUVEC TERT2 [nTPM]":"72.0","Cell RNA - JURKAT [nTPM]":"39.2","Cell RNA - K-562 [nTPM]":"75.1","Cell RNA - Karpas-707 [nTPM]":"41.5","Cell RNA - LHCN-M2 [nTPM]":"41.6","Cell RNA - MCF7 [nTPM]":"172.8","Cell RNA - MOLT-4 [nTPM]":"115.0","Cell RNA - NB-4 [nTPM]":"106.4","Cell RNA - NTERA-2 [nTPM]":"42.9","Cell RNA - OE19 [nTPM]":"124.4","Cell RNA - PC-3 [nTPM]":"189.0","Cell RNA - REH [nTPM]":"90.1","Cell RNA - RH-30 [nTPM]":"65.7","Cell RNA - RPMI-8226 [nTPM]":"111.5","Cell RNA - RPTEC TERT1 [nTPM]":"47.7","Cell RNA - RT4 [nTPM]":"59.7","Cell RNA - SCLC-21H [nTPM]":"54.0","Cell RNA - SH-SY5Y [nTPM]":"65.7","Cell RNA - SiHa [nTPM]":"18.7","Cell RNA - SK-BR-3 [nTPM]":"71.0","Cell RNA - SK-MEL-30 [nTPM]":"113.7","Cell RNA - SuSa [nTPM]":"23.9","Cell RNA - T-47d [nTPM]":"38.4","Cell RNA - THP-1 [nTPM]":"58.8","Cell RNA - TIME [nTPM]":"41.1","Cell RNA - U-138 MG [nTPM]":"25.6","Cell RNA - U-2 OS [nTPM]":"88.5","Cell RNA - U-2197 [nTPM]":"89.5","Cell RNA - U-251 MG [nTPM]":"142.0","Cell RNA - U-266\/70 [nTPM]":"86.3","Cell RNA - U-266\/84 [nTPM]":"107.2","Cell RNA - U-698 [nTPM]":"196.0","Cell RNA - U-87 MG [nTPM]":"34.7","Cell RNA - U-937 [nTPM]":"91.0","Cell RNA - WM-115 [nTPM]":"75.5","Blood RNA - basophil [nTPM]":"35.3","Blood RNA - classical monocyte [nTPM]":"53.1","Blood RNA - eosinophil [nTPM]":"81.3","Blood RNA - gdT-cell [nTPM]":"60.0","Blood RNA - intermediate monocyte [nTPM]":"65.3","Blood RNA - MAIT T-cell [nTPM]":"78.1","Blood RNA - memory B-cell [nTPM]":"75.2","Blood RNA - memory CD4 T-cell [nTPM]":"63.4","Blood RNA - memory CD8 T-cell [nTPM]":"65.6","Blood RNA - myeloid DC [nTPM]":"69.4","Blood RNA - naive B-cell [nTPM]":"77.7","Blood RNA - naive CD4 T-cell [nTPM]":"37.4","Blood RNA - naive CD8 T-cell [nTPM]":"56.7","Blood RNA - neutrophil [nTPM]":"49.8","Blood RNA - NK-cell [nTPM]":"64.7","Blood RNA - non-classical monocyte [nTPM]":"76.0","Blood RNA - plasmacytoid DC [nTPM]":"75.9","Blood RNA - T-reg [nTPM]":"102.9","Blood RNA - total PBMC [nTPM]":"70.6","Brain RNA - amygdala [nTPM]":"19.6","Brain RNA - basal ganglia [nTPM]":"20.1","Brain RNA - cerebellum [nTPM]":"20.4","Brain RNA - cerebral cortex [nTPM]":"27.2","Brain RNA - hippocampal formation [nTPM]":"20.0","Brain RNA - hypothalamus [nTPM]":"21.8","Brain RNA - medulla oblongata [nTPM]":"20.8","Brain RNA - midbrain [nTPM]":"20.3","Brain RNA - pons [nTPM]":"20.8","Brain RNA - spinal cord [nTPM]":"20.4","Brain RNA - thalamus [nTPM]":"21.2","Brain RNA - white matter [nTPM]":"20.4","Single Cell Type RNA - Adipocytes [nTPM]":"126.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"30.2","Single Cell Type RNA - Astrocytes [nTPM]":"27.1","Single Cell Type RNA - B-cells [nTPM]":"76.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"70.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"66.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"90.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"68.3","Single Cell Type RNA - Bipolar cells [nTPM]":"29.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"82.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"113.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"45.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"47.1","Single Cell Type RNA - Club cells [nTPM]":"52.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"125.9","Single Cell Type RNA - dendritic cells [nTPM]":"77.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"94.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"95.9","Single Cell Type RNA - Ductal cells [nTPM]":"121.1","Single Cell Type RNA - Early spermatids [nTPM]":"2.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"46.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"60.7","Single Cell Type RNA - Endothelial cells [nTPM]":"98.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"58.1","Single Cell Type RNA - Erythroid cells [nTPM]":"78.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"149.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"179.0","Single Cell Type RNA - Fibroblasts [nTPM]":"57.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"76.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"43.4","Single Cell Type RNA - granulocytes [nTPM]":"67.9","Single Cell Type RNA - Granulosa cells [nTPM]":"64.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"77.8","Single Cell Type RNA - Hepatocytes [nTPM]":"78.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"123.1","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"92.2","Single Cell Type RNA - Ionocytes [nTPM]":"54.9","Single Cell Type RNA - Kupffer cells [nTPM]":"66.5","Single Cell Type RNA - Langerhans cells [nTPM]":"96.0","Single Cell Type RNA - Late spermatids [nTPM]":"12.5","Single Cell Type RNA - Leydig cells [nTPM]":"46.6","Single Cell Type RNA - Macrophages [nTPM]":"66.4","Single Cell Type RNA - Melanocytes [nTPM]":"119.2","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"84.8","Single Cell Type RNA - Muller glia cells [nTPM]":"37.9","Single Cell Type RNA - NK-cells [nTPM]":"85.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"144.6","Single Cell Type RNA - Paneth cells [nTPM]":"75.2","Single Cell Type RNA - Peritubular cells [nTPM]":"46.6","Single Cell Type RNA - Plasma cells [nTPM]":"104.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"136.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"91.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"197.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"40.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"30.4","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"56.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"98.3","Single Cell Type RNA - Spermatocytes [nTPM]":"7.6","Single Cell Type RNA - Spermatogonia [nTPM]":"33.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"120.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"90.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"108.8","Single Cell Type RNA - T-cells [nTPM]":"74.8","Single Cell Type RNA - Theca cells [nTPM]":"97.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"110.3","Single Cell Type RNA - Urothelial cells [nTPM]":"85.9"},{"Gene":"NADK2","Gene synonym":["C5orf33","FLJ30596","MNADK","NADKD1"],"Ensembl":"ENSG00000152620","Gene description":"NAD kinase 2, mitochondrial","Uniprot":["Q4G0N4"],"Chromosome":"5","Position":"36192589-36242279","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"liver":"328.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Astrocytes":"105.4","Early spermatids":"324.5","Hepatocytes":"211.9","Late spermatids":"154.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"36.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038366","HPA038367","HPA061492"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"30000","Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 23: Spermatids - Flagellum & Golgi organization","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA038366":"AB_2675977","HPA038367":"AB_10672743","HPA061492":"AB_2684538"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Tissue RNA - adipose tissue [nTPM]":"13.6","Tissue RNA - adrenal gland [nTPM]":"20.1","Tissue RNA - amygdala [nTPM]":"26.6","Tissue RNA - appendix [nTPM]":"9.3","Tissue RNA - basal ganglia [nTPM]":"23.3","Tissue RNA - bone marrow [nTPM]":"10.6","Tissue RNA - breast [nTPM]":"15.4","Tissue RNA - cerebellum [nTPM]":"21.9","Tissue RNA - cerebral cortex [nTPM]":"24.2","Tissue RNA - cervix [nTPM]":"13.7","Tissue RNA - choroid plexus [nTPM]":"14.0","Tissue RNA - colon [nTPM]":"13.9","Tissue RNA - duodenum [nTPM]":"16.6","Tissue RNA - endometrium 1 [nTPM]":"13.3","Tissue RNA - epididymis [nTPM]":"7.9","Tissue RNA - esophagus [nTPM]":"10.4","Tissue RNA - fallopian tube [nTPM]":"12.7","Tissue RNA - gallbladder [nTPM]":"11.9","Tissue RNA - heart muscle [nTPM]":"20.2","Tissue RNA - hippocampal formation [nTPM]":"22.2","Tissue RNA - hypothalamus [nTPM]":"27.1","Tissue RNA - kidney [nTPM]":"23.2","Tissue RNA - liver [nTPM]":"328.0","Tissue RNA - lung [nTPM]":"8.4","Tissue RNA - lymph node [nTPM]":"9.5","Tissue RNA - medulla oblongata [nTPM]":"25.4","Tissue RNA - midbrain [nTPM]":"27.4","Tissue RNA - ovary [nTPM]":"19.6","Tissue RNA - pancreas [nTPM]":"26.9","Tissue RNA - parathyroid gland [nTPM]":"10.7","Tissue RNA - pituitary gland [nTPM]":"5.5","Tissue RNA - placenta [nTPM]":"16.9","Tissue RNA - pons [nTPM]":"25.3","Tissue RNA - prostate [nTPM]":"19.0","Tissue RNA - rectum [nTPM]":"13.8","Tissue RNA - retina [nTPM]":"11.2","Tissue RNA - salivary gland [nTPM]":"13.0","Tissue RNA - seminal vesicle [nTPM]":"16.2","Tissue RNA - skeletal muscle [nTPM]":"29.4","Tissue RNA - skin 1 [nTPM]":"6.6","Tissue RNA - small intestine [nTPM]":"12.9","Tissue RNA - smooth muscle [nTPM]":"14.2","Tissue RNA - spinal cord [nTPM]":"31.0","Tissue RNA - spleen [nTPM]":"8.6","Tissue RNA - stomach 1 [nTPM]":"17.1","Tissue RNA - testis [nTPM]":"18.2","Tissue RNA - thalamus [nTPM]":"25.3","Tissue RNA - thymus [nTPM]":"10.3","Tissue RNA - thyroid gland [nTPM]":"17.3","Tissue RNA - tongue [nTPM]":"29.8","Tissue RNA - tonsil [nTPM]":"11.4","Tissue RNA - urinary bladder [nTPM]":"27.9","Tissue RNA - vagina [nTPM]":"8.8","Tissue RNA - white matter [nTPM]":"30.3","Cell RNA - A-431 [nTPM]":"21.5","Cell RNA - A549 [nTPM]":"14.6","Cell RNA - AF22 [nTPM]":"22.4","Cell RNA - AN3-CA [nTPM]":"23.5","Cell RNA - ASC diff [nTPM]":"32.2","Cell RNA - ASC TERT1 [nTPM]":"27.2","Cell RNA - BEWO [nTPM]":"27.5","Cell RNA - BJ [nTPM]":"19.5","Cell RNA - BJ hTERT+ [nTPM]":"13.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.2","Cell RNA - CACO-2 [nTPM]":"41.4","Cell RNA - CAPAN-2 [nTPM]":"27.4","Cell RNA - Daudi [nTPM]":"74.3","Cell RNA - EFO-21 [nTPM]":"14.0","Cell RNA - fHDF\/TERT166 [nTPM]":"23.3","Cell RNA - GAMG [nTPM]":"23.0","Cell RNA - HaCaT [nTPM]":"14.9","Cell RNA - HAP1 [nTPM]":"20.0","Cell RNA - HBEC3-KT [nTPM]":"14.3","Cell RNA - HBF TERT88 [nTPM]":"24.2","Cell RNA - HDLM-2 [nTPM]":"21.2","Cell RNA - HEK 293 [nTPM]":"16.3","Cell RNA - HEL [nTPM]":"22.0","Cell RNA - HeLa [nTPM]":"43.1","Cell RNA - Hep G2 [nTPM]":"23.9","Cell RNA - HHSteC [nTPM]":"22.7","Cell RNA - HL-60 [nTPM]":"46.5","Cell RNA - HMC-1 [nTPM]":"8.0","Cell RNA - HSkMC [nTPM]":"28.9","Cell RNA - hTCEpi [nTPM]":"22.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.6","Cell RNA - hTERT-HME1 [nTPM]":"29.9","Cell RNA - hTERT-RPE1 [nTPM]":"22.4","Cell RNA - HUVEC TERT2 [nTPM]":"18.4","Cell RNA - JURKAT [nTPM]":"30.2","Cell RNA - K-562 [nTPM]":"52.0","Cell RNA - Karpas-707 [nTPM]":"27.8","Cell RNA - LHCN-M2 [nTPM]":"18.0","Cell RNA - MCF7 [nTPM]":"9.0","Cell RNA - MOLT-4 [nTPM]":"42.3","Cell RNA - NB-4 [nTPM]":"18.2","Cell RNA - NTERA-2 [nTPM]":"10.7","Cell RNA - OE19 [nTPM]":"18.1","Cell RNA - PC-3 [nTPM]":"19.2","Cell RNA - REH [nTPM]":"40.2","Cell RNA - RH-30 [nTPM]":"51.6","Cell RNA - RPMI-8226 [nTPM]":"15.8","Cell RNA - RPTEC TERT1 [nTPM]":"24.2","Cell RNA - RT4 [nTPM]":"18.2","Cell RNA - SCLC-21H [nTPM]":"8.7","Cell RNA - SH-SY5Y [nTPM]":"20.1","Cell RNA - SiHa [nTPM]":"102.0","Cell RNA - SK-BR-3 [nTPM]":"32.4","Cell RNA - SK-MEL-30 [nTPM]":"10.5","Cell RNA - SuSa [nTPM]":"16.7","Cell RNA - T-47d [nTPM]":"22.9","Cell RNA - THP-1 [nTPM]":"39.8","Cell RNA - TIME [nTPM]":"15.1","Cell RNA - U-138 MG [nTPM]":"34.1","Cell RNA - U-2 OS [nTPM]":"18.2","Cell RNA - U-2197 [nTPM]":"27.0","Cell RNA - U-251 MG [nTPM]":"23.9","Cell RNA - U-266\/70 [nTPM]":"23.7","Cell RNA - U-266\/84 [nTPM]":"30.3","Cell RNA - U-698 [nTPM]":"23.2","Cell RNA - U-87 MG [nTPM]":"14.5","Cell RNA - U-937 [nTPM]":"57.2","Cell RNA - WM-115 [nTPM]":"14.2","Blood RNA - basophil [nTPM]":"8.2","Blood RNA - classical monocyte [nTPM]":"1.2","Blood RNA - eosinophil [nTPM]":"1.1","Blood RNA - gdT-cell [nTPM]":"1.3","Blood RNA - intermediate monocyte [nTPM]":"1.4","Blood RNA - MAIT T-cell [nTPM]":"1.8","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"1.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.5","Blood RNA - myeloid DC [nTPM]":"2.3","Blood RNA - naive B-cell [nTPM]":"5.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.6","Blood RNA - naive CD8 T-cell [nTPM]":"1.4","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"6.7","Blood RNA - non-classical monocyte [nTPM]":"3.3","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"2.1","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"26.6","Brain RNA - basal ganglia [nTPM]":"23.3","Brain RNA - cerebellum [nTPM]":"21.9","Brain RNA - cerebral cortex [nTPM]":"24.2","Brain RNA - hippocampal formation [nTPM]":"22.2","Brain RNA - hypothalamus [nTPM]":"27.1","Brain RNA - medulla oblongata [nTPM]":"25.4","Brain RNA - midbrain [nTPM]":"27.4","Brain RNA - pons [nTPM]":"25.3","Brain RNA - spinal cord [nTPM]":"31.0","Brain RNA - thalamus [nTPM]":"25.3","Brain RNA - white matter [nTPM]":"30.3","Single Cell Type RNA - Adipocytes [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.9","Single Cell Type RNA - Astrocytes [nTPM]":"105.4","Single Cell Type RNA - B-cells [nTPM]":"7.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"5.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"29.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"7.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.2","Single Cell Type RNA - dendritic cells [nTPM]":"9.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"25.4","Single Cell Type RNA - Ductal cells [nTPM]":"5.0","Single Cell Type RNA - Early spermatids [nTPM]":"324.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.4","Single Cell Type RNA - Endothelial cells [nTPM]":"6.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"13.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.9","Single Cell Type RNA - Fibroblasts [nTPM]":"12.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"10.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.1","Single Cell Type RNA - Hepatocytes [nTPM]":"211.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.9","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.7","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"10.4","Single Cell Type RNA - Langerhans cells [nTPM]":"9.6","Single Cell Type RNA - Late spermatids [nTPM]":"154.9","Single Cell Type RNA - Leydig cells [nTPM]":"19.9","Single Cell Type RNA - Macrophages [nTPM]":"6.4","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"3.7","Single Cell Type RNA - Muller glia cells [nTPM]":"16.9","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"21.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"23.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.9","Single Cell Type RNA - Paneth cells [nTPM]":"8.8","Single Cell Type RNA - Peritubular cells [nTPM]":"23.0","Single Cell Type RNA - Plasma cells [nTPM]":"14.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.5","Single Cell Type RNA - Spermatocytes [nTPM]":"35.1","Single Cell Type RNA - Spermatogonia [nTPM]":"11.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.3","Single Cell Type RNA - T-cells [nTPM]":"6.9","Single Cell Type RNA - Theca cells [nTPM]":"26.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.6","Single Cell Type RNA - Urothelial cells [nTPM]":"12.3"},{"Gene":"NADSYN1","Gene synonym":["FLJ10631"],"Ensembl":"ENSG00000172890","Gene description":"NAD synthetase 1","Uniprot":["Q6IA69"],"Chromosome":"11","Position":"71453109-71524107","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Ligase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017798","HPA038523","HPA038524"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Vesicles"],"Subcellular additional location":["Golgi apparatus","Cytosol"],"Antibody RRID":{"CAB017798":null,"HPA038523":"AB_2676060","HPA038524":"AB_2676061"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.17e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.72e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.10e-4"},"Tissue RNA - adipose tissue [nTPM]":"29.5","Tissue RNA - adrenal gland [nTPM]":"34.1","Tissue RNA - amygdala [nTPM]":"18.8","Tissue RNA - appendix [nTPM]":"24.1","Tissue RNA - basal ganglia [nTPM]":"20.4","Tissue RNA - bone marrow [nTPM]":"67.6","Tissue RNA - breast [nTPM]":"26.2","Tissue RNA - cerebellum [nTPM]":"18.5","Tissue RNA - cerebral cortex [nTPM]":"21.2","Tissue RNA - cervix [nTPM]":"30.4","Tissue RNA - choroid plexus [nTPM]":"20.3","Tissue RNA - colon [nTPM]":"48.6","Tissue RNA - duodenum [nTPM]":"39.5","Tissue RNA - endometrium 1 [nTPM]":"26.0","Tissue RNA - epididymis [nTPM]":"24.2","Tissue RNA - esophagus [nTPM]":"56.3","Tissue RNA - fallopian tube [nTPM]":"31.2","Tissue RNA - gallbladder [nTPM]":"25.8","Tissue RNA - heart muscle [nTPM]":"20.3","Tissue RNA - hippocampal formation [nTPM]":"17.8","Tissue RNA - hypothalamus [nTPM]":"18.3","Tissue RNA - kidney [nTPM]":"33.2","Tissue RNA - liver [nTPM]":"49.8","Tissue RNA - lung [nTPM]":"35.3","Tissue RNA - lymph node [nTPM]":"33.3","Tissue RNA - medulla oblongata [nTPM]":"22.4","Tissue RNA - midbrain [nTPM]":"19.6","Tissue RNA - ovary [nTPM]":"27.6","Tissue RNA - pancreas [nTPM]":"29.5","Tissue RNA - parathyroid gland [nTPM]":"13.4","Tissue RNA - pituitary gland [nTPM]":"36.0","Tissue RNA - placenta [nTPM]":"16.5","Tissue RNA - pons [nTPM]":"21.0","Tissue RNA - prostate [nTPM]":"45.3","Tissue RNA - rectum [nTPM]":"36.0","Tissue RNA - retina [nTPM]":"6.9","Tissue RNA - salivary gland [nTPM]":"32.9","Tissue RNA - seminal vesicle [nTPM]":"22.8","Tissue RNA - skeletal muscle [nTPM]":"11.0","Tissue RNA - skin 1 [nTPM]":"31.1","Tissue RNA - small intestine [nTPM]":"51.1","Tissue RNA - smooth muscle [nTPM]":"19.3","Tissue RNA - spinal cord [nTPM]":"18.8","Tissue RNA - spleen [nTPM]":"58.4","Tissue RNA - stomach 1 [nTPM]":"34.3","Tissue RNA - testis [nTPM]":"25.6","Tissue RNA - thalamus [nTPM]":"21.7","Tissue RNA - thymus [nTPM]":"27.9","Tissue RNA - thyroid gland [nTPM]":"31.8","Tissue RNA - tongue [nTPM]":"5.1","Tissue RNA - tonsil [nTPM]":"28.2","Tissue RNA - urinary bladder [nTPM]":"43.4","Tissue RNA - vagina [nTPM]":"33.4","Tissue RNA - white matter [nTPM]":"24.4","Cell RNA - A-431 [nTPM]":"15.9","Cell RNA - A549 [nTPM]":"37.8","Cell RNA - AF22 [nTPM]":"12.0","Cell RNA - AN3-CA [nTPM]":"21.6","Cell RNA - ASC diff [nTPM]":"35.0","Cell RNA - ASC TERT1 [nTPM]":"50.6","Cell RNA - BEWO [nTPM]":"32.4","Cell RNA - BJ [nTPM]":"29.7","Cell RNA - BJ hTERT+ [nTPM]":"27.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.0","Cell RNA - CACO-2 [nTPM]":"32.4","Cell RNA - CAPAN-2 [nTPM]":"25.7","Cell RNA - Daudi [nTPM]":"13.4","Cell RNA - EFO-21 [nTPM]":"33.1","Cell RNA - fHDF\/TERT166 [nTPM]":"35.3","Cell RNA - GAMG [nTPM]":"20.7","Cell RNA - HaCaT [nTPM]":"55.2","Cell RNA - HAP1 [nTPM]":"15.9","Cell RNA - HBEC3-KT [nTPM]":"42.6","Cell RNA - HBF TERT88 [nTPM]":"8.2","Cell RNA - HDLM-2 [nTPM]":"27.9","Cell RNA - HEK 293 [nTPM]":"12.8","Cell RNA - HEL [nTPM]":"22.2","Cell RNA - HeLa [nTPM]":"27.6","Cell RNA - Hep G2 [nTPM]":"36.3","Cell RNA - HHSteC [nTPM]":"43.3","Cell RNA - HL-60 [nTPM]":"45.1","Cell RNA - HMC-1 [nTPM]":"40.9","Cell RNA - HSkMC [nTPM]":"72.0","Cell RNA - hTCEpi [nTPM]":"65.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.9","Cell RNA - hTERT-HME1 [nTPM]":"17.8","Cell RNA - hTERT-RPE1 [nTPM]":"34.9","Cell RNA - HUVEC TERT2 [nTPM]":"54.6","Cell RNA - JURKAT [nTPM]":"24.2","Cell RNA - K-562 [nTPM]":"11.9","Cell RNA - Karpas-707 [nTPM]":"18.5","Cell RNA - LHCN-M2 [nTPM]":"21.9","Cell RNA - MCF7 [nTPM]":"49.7","Cell RNA - MOLT-4 [nTPM]":"22.4","Cell RNA - NB-4 [nTPM]":"29.9","Cell RNA - NTERA-2 [nTPM]":"7.0","Cell RNA - OE19 [nTPM]":"69.6","Cell RNA - PC-3 [nTPM]":"21.3","Cell RNA - REH [nTPM]":"27.5","Cell RNA - RH-30 [nTPM]":"37.2","Cell RNA - RPMI-8226 [nTPM]":"13.5","Cell RNA - RPTEC TERT1 [nTPM]":"37.8","Cell RNA - RT4 [nTPM]":"72.1","Cell RNA - SCLC-21H [nTPM]":"8.9","Cell RNA - SH-SY5Y [nTPM]":"12.7","Cell RNA - SiHa [nTPM]":"21.2","Cell RNA - SK-BR-3 [nTPM]":"27.9","Cell RNA - SK-MEL-30 [nTPM]":"56.0","Cell RNA - SuSa [nTPM]":"17.9","Cell RNA - T-47d [nTPM]":"24.9","Cell RNA - THP-1 [nTPM]":"24.4","Cell RNA - TIME [nTPM]":"66.2","Cell RNA - U-138 MG [nTPM]":"16.7","Cell RNA - U-2 OS [nTPM]":"14.2","Cell RNA - U-2197 [nTPM]":"30.9","Cell RNA - U-251 MG [nTPM]":"11.8","Cell RNA - U-266\/70 [nTPM]":"24.3","Cell RNA - U-266\/84 [nTPM]":"11.0","Cell RNA - U-698 [nTPM]":"11.7","Cell RNA - U-87 MG [nTPM]":"29.9","Cell RNA - U-937 [nTPM]":"25.6","Cell RNA - WM-115 [nTPM]":"12.0","Blood RNA - basophil [nTPM]":"6.1","Blood RNA - classical monocyte [nTPM]":"28.0","Blood RNA - eosinophil [nTPM]":"17.3","Blood RNA - gdT-cell [nTPM]":"15.3","Blood RNA - intermediate monocyte [nTPM]":"25.0","Blood RNA - MAIT T-cell [nTPM]":"12.7","Blood RNA - memory B-cell [nTPM]":"12.2","Blood RNA - memory CD4 T-cell [nTPM]":"13.5","Blood RNA - memory CD8 T-cell [nTPM]":"13.8","Blood RNA - myeloid DC [nTPM]":"31.1","Blood RNA - naive B-cell [nTPM]":"9.2","Blood RNA - naive CD4 T-cell [nTPM]":"8.8","Blood RNA - naive CD8 T-cell [nTPM]":"11.4","Blood RNA - neutrophil [nTPM]":"17.7","Blood RNA - NK-cell [nTPM]":"16.3","Blood RNA - non-classical monocyte [nTPM]":"22.6","Blood RNA - plasmacytoid DC [nTPM]":"23.0","Blood RNA - T-reg [nTPM]":"17.7","Blood RNA - total PBMC [nTPM]":"21.4","Brain RNA - amygdala [nTPM]":"18.8","Brain RNA - basal ganglia [nTPM]":"20.4","Brain RNA - cerebellum [nTPM]":"18.5","Brain RNA - cerebral cortex [nTPM]":"21.2","Brain RNA - hippocampal formation [nTPM]":"17.8","Brain RNA - hypothalamus [nTPM]":"18.3","Brain RNA - medulla oblongata [nTPM]":"22.4","Brain RNA - midbrain [nTPM]":"19.6","Brain RNA - pons [nTPM]":"21.0","Brain RNA - spinal cord [nTPM]":"18.8","Brain RNA - thalamus [nTPM]":"21.7","Brain RNA - white matter [nTPM]":"24.4","Single Cell Type RNA - Adipocytes [nTPM]":"12.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"32.3","Single Cell Type RNA - Astrocytes [nTPM]":"4.2","Single Cell Type RNA - B-cells [nTPM]":"24.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.2","Single Cell Type RNA - Bipolar cells [nTPM]":"7.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"19.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"17.4","Single Cell Type RNA - dendritic cells [nTPM]":"27.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"65.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"16.5","Single Cell Type RNA - Early spermatids [nTPM]":"22.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"21.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.1","Single Cell Type RNA - Endothelial cells [nTPM]":"15.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"23.4","Single Cell Type RNA - Erythroid cells [nTPM]":"20.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.5","Single Cell Type RNA - Fibroblasts [nTPM]":"12.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"51.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.7","Single Cell Type RNA - granulocytes [nTPM]":"22.1","Single Cell Type RNA - Granulosa cells [nTPM]":"23.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.9","Single Cell Type RNA - Hepatocytes [nTPM]":"16.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.1","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"30.3","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"23.2","Single Cell Type RNA - Langerhans cells [nTPM]":"18.5","Single Cell Type RNA - Late spermatids [nTPM]":"60.9","Single Cell Type RNA - Leydig cells [nTPM]":"9.3","Single Cell Type RNA - Macrophages [nTPM]":"25.4","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"25.8","Single Cell Type RNA - Muller glia cells [nTPM]":"5.9","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.0","Single Cell Type RNA - Paneth cells [nTPM]":"55.8","Single Cell Type RNA - Peritubular cells [nTPM]":"10.1","Single Cell Type RNA - Plasma cells [nTPM]":"18.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"73.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.3","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.8","Single Cell Type RNA - Spermatocytes [nTPM]":"15.9","Single Cell Type RNA - Spermatogonia [nTPM]":"5.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"38.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.2","Single Cell Type RNA - T-cells [nTPM]":"22.3","Single Cell Type RNA - Theca cells [nTPM]":"17.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"43.7","Single Cell Type RNA - Urothelial cells [nTPM]":"24.2"},{"Gene":"NAGA","Gene synonym":["D22S674"],"Ensembl":"ENSG00000198951","Gene description":"Alpha-N-acetylgalactosaminidase","Uniprot":["P17050"],"Chromosome":"22","Position":"42058334-42070842","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"65.0","Hofbauer cells":"91.6","Kupffer cells":"64.4","monocytes":"65.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"classical monocyte":"202.5","intermediate monocyte":"249.1","myeloid DC":"195.2","non-classical monocyte":"257.9","plasmacytoid DC":"119.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"195.2","monocytes":"257.9"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"190.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000649"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2200000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA000649":"AB_1079448"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Tissue RNA - adipose tissue [nTPM]":"21.4","Tissue RNA - adrenal gland [nTPM]":"12.7","Tissue RNA - amygdala [nTPM]":"9.3","Tissue RNA - appendix [nTPM]":"32.3","Tissue RNA - basal ganglia [nTPM]":"10.4","Tissue RNA - bone marrow [nTPM]":"20.1","Tissue RNA - breast [nTPM]":"13.4","Tissue RNA - cerebellum [nTPM]":"10.3","Tissue RNA - cerebral cortex [nTPM]":"10.1","Tissue RNA - cervix [nTPM]":"20.6","Tissue RNA - choroid plexus [nTPM]":"17.0","Tissue RNA - colon [nTPM]":"26.1","Tissue RNA - duodenum [nTPM]":"20.4","Tissue RNA - endometrium 1 [nTPM]":"17.2","Tissue RNA - epididymis [nTPM]":"12.4","Tissue RNA - esophagus [nTPM]":"17.2","Tissue RNA - fallopian tube [nTPM]":"20.0","Tissue RNA - gallbladder [nTPM]":"22.1","Tissue RNA - heart muscle [nTPM]":"16.0","Tissue RNA - hippocampal formation [nTPM]":"8.9","Tissue RNA - hypothalamus [nTPM]":"11.5","Tissue RNA - kidney [nTPM]":"14.9","Tissue RNA - liver [nTPM]":"31.9","Tissue RNA - lung [nTPM]":"27.1","Tissue RNA - lymph node [nTPM]":"20.8","Tissue RNA - medulla oblongata [nTPM]":"13.9","Tissue RNA - midbrain [nTPM]":"10.8","Tissue RNA - ovary [nTPM]":"17.0","Tissue RNA - pancreas [nTPM]":"11.4","Tissue RNA - parathyroid gland [nTPM]":"39.2","Tissue RNA - pituitary gland [nTPM]":"11.7","Tissue RNA - placenta [nTPM]":"42.8","Tissue RNA - pons [nTPM]":"12.6","Tissue RNA - prostate [nTPM]":"18.2","Tissue RNA - rectum [nTPM]":"26.7","Tissue RNA - retina [nTPM]":"7.7","Tissue RNA - salivary gland [nTPM]":"17.3","Tissue RNA - seminal vesicle [nTPM]":"18.6","Tissue RNA - skeletal muscle [nTPM]":"7.7","Tissue RNA - skin 1 [nTPM]":"13.4","Tissue RNA - small intestine [nTPM]":"24.2","Tissue RNA - smooth muscle [nTPM]":"28.3","Tissue RNA - spinal cord [nTPM]":"12.2","Tissue RNA - spleen [nTPM]":"20.3","Tissue RNA - stomach 1 [nTPM]":"16.6","Tissue RNA - testis [nTPM]":"9.0","Tissue RNA - thalamus [nTPM]":"12.0","Tissue RNA - thymus [nTPM]":"13.9","Tissue RNA - thyroid gland [nTPM]":"15.1","Tissue RNA - tongue [nTPM]":"12.3","Tissue RNA - tonsil [nTPM]":"19.0","Tissue RNA - urinary bladder [nTPM]":"24.8","Tissue RNA - vagina [nTPM]":"13.7","Tissue RNA - white matter [nTPM]":"14.4","Cell RNA - A-431 [nTPM]":"27.8","Cell RNA - A549 [nTPM]":"14.0","Cell RNA - AF22 [nTPM]":"21.7","Cell RNA - AN3-CA [nTPM]":"38.9","Cell RNA - ASC diff [nTPM]":"37.0","Cell RNA - ASC TERT1 [nTPM]":"41.9","Cell RNA - BEWO [nTPM]":"15.9","Cell RNA - BJ [nTPM]":"22.4","Cell RNA - BJ hTERT+ [nTPM]":"45.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"37.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"39.2","Cell RNA - CACO-2 [nTPM]":"31.4","Cell RNA - CAPAN-2 [nTPM]":"39.9","Cell RNA - Daudi [nTPM]":"13.5","Cell RNA - EFO-21 [nTPM]":"13.5","Cell RNA - fHDF\/TERT166 [nTPM]":"49.1","Cell RNA - GAMG [nTPM]":"22.9","Cell RNA - HaCaT [nTPM]":"19.2","Cell RNA - HAP1 [nTPM]":"16.7","Cell RNA - HBEC3-KT [nTPM]":"27.4","Cell RNA - HBF TERT88 [nTPM]":"22.3","Cell RNA - HDLM-2 [nTPM]":"31.0","Cell RNA - HEK 293 [nTPM]":"21.2","Cell RNA - HEL [nTPM]":"33.5","Cell RNA - HeLa [nTPM]":"20.1","Cell RNA - Hep G2 [nTPM]":"21.5","Cell RNA - HHSteC [nTPM]":"21.5","Cell RNA - HL-60 [nTPM]":"28.1","Cell RNA - HMC-1 [nTPM]":"190.4","Cell RNA - HSkMC [nTPM]":"28.9","Cell RNA - hTCEpi [nTPM]":"23.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"34.0","Cell RNA - hTERT-HME1 [nTPM]":"14.4","Cell RNA - hTERT-RPE1 [nTPM]":"19.5","Cell RNA - HUVEC TERT2 [nTPM]":"63.4","Cell RNA - JURKAT [nTPM]":"11.6","Cell RNA - K-562 [nTPM]":"12.4","Cell RNA - Karpas-707 [nTPM]":"56.0","Cell RNA - LHCN-M2 [nTPM]":"30.2","Cell RNA - MCF7 [nTPM]":"32.3","Cell RNA - MOLT-4 [nTPM]":"10.4","Cell RNA - NB-4 [nTPM]":"11.5","Cell RNA - NTERA-2 [nTPM]":"5.8","Cell RNA - OE19 [nTPM]":"25.3","Cell RNA - PC-3 [nTPM]":"18.5","Cell RNA - REH [nTPM]":"23.0","Cell RNA - RH-30 [nTPM]":"11.0","Cell RNA - RPMI-8226 [nTPM]":"24.2","Cell RNA - RPTEC TERT1 [nTPM]":"29.4","Cell RNA - RT4 [nTPM]":"32.7","Cell RNA - SCLC-21H [nTPM]":"6.7","Cell RNA - SH-SY5Y [nTPM]":"7.7","Cell RNA - SiHa [nTPM]":"29.8","Cell RNA - SK-BR-3 [nTPM]":"27.0","Cell RNA - SK-MEL-30 [nTPM]":"29.3","Cell RNA - SuSa [nTPM]":"19.1","Cell RNA - T-47d [nTPM]":"40.4","Cell RNA - THP-1 [nTPM]":"50.9","Cell RNA - TIME [nTPM]":"34.4","Cell RNA - U-138 MG [nTPM]":"26.6","Cell RNA - U-2 OS [nTPM]":"31.8","Cell RNA - U-2197 [nTPM]":"17.1","Cell RNA - U-251 MG [nTPM]":"20.7","Cell RNA - U-266\/70 [nTPM]":"30.9","Cell RNA - U-266\/84 [nTPM]":"33.3","Cell RNA - U-698 [nTPM]":"10.9","Cell RNA - U-87 MG [nTPM]":"28.3","Cell RNA - U-937 [nTPM]":"52.7","Cell RNA - WM-115 [nTPM]":"33.4","Blood RNA - basophil [nTPM]":"36.5","Blood RNA - classical monocyte [nTPM]":"202.5","Blood RNA - eosinophil [nTPM]":"25.1","Blood RNA - gdT-cell [nTPM]":"13.6","Blood RNA - intermediate monocyte [nTPM]":"249.1","Blood RNA - MAIT T-cell [nTPM]":"13.8","Blood RNA - memory B-cell [nTPM]":"10.5","Blood RNA - memory CD4 T-cell [nTPM]":"14.1","Blood RNA - memory CD8 T-cell [nTPM]":"12.7","Blood RNA - myeloid DC [nTPM]":"195.2","Blood RNA - naive B-cell [nTPM]":"6.9","Blood RNA - naive CD4 T-cell [nTPM]":"9.2","Blood RNA - naive CD8 T-cell [nTPM]":"8.4","Blood RNA - neutrophil [nTPM]":"9.9","Blood RNA - NK-cell [nTPM]":"18.8","Blood RNA - non-classical monocyte [nTPM]":"257.9","Blood RNA - plasmacytoid DC [nTPM]":"119.8","Blood RNA - T-reg [nTPM]":"18.3","Blood RNA - total PBMC [nTPM]":"121.0","Brain RNA - amygdala [nTPM]":"9.3","Brain RNA - basal ganglia [nTPM]":"10.4","Brain RNA - cerebellum [nTPM]":"10.3","Brain RNA - cerebral cortex [nTPM]":"10.1","Brain RNA - hippocampal formation [nTPM]":"8.9","Brain RNA - hypothalamus [nTPM]":"11.5","Brain RNA - medulla oblongata [nTPM]":"13.9","Brain RNA - midbrain [nTPM]":"10.8","Brain RNA - pons [nTPM]":"12.6","Brain RNA - spinal cord [nTPM]":"12.2","Brain RNA - thalamus [nTPM]":"12.0","Brain RNA - white matter [nTPM]":"14.4","Single Cell Type RNA - Adipocytes [nTPM]":"6.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.7","Single Cell Type RNA - Astrocytes [nTPM]":"4.6","Single Cell Type RNA - B-cells [nTPM]":"8.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"2.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"11.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"46.1","Single Cell Type RNA - dendritic cells [nTPM]":"11.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"27.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"15.4","Single Cell Type RNA - Early spermatids [nTPM]":"15.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.8","Single Cell Type RNA - Endothelial cells [nTPM]":"11.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"12.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"65.0","Single Cell Type RNA - Fibroblasts [nTPM]":"13.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.2","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"3.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.3","Single Cell Type RNA - Hepatocytes [nTPM]":"33.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"91.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"64.4","Single Cell Type RNA - Langerhans cells [nTPM]":"36.3","Single Cell Type RNA - Late spermatids [nTPM]":"17.9","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"52.5","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"65.8","Single Cell Type RNA - Muller glia cells [nTPM]":"5.9","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.0","Single Cell Type RNA - Paneth cells [nTPM]":"23.9","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"22.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"40.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.4","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.0","Single Cell Type RNA - Spermatocytes [nTPM]":"10.7","Single Cell Type RNA - Spermatogonia [nTPM]":"5.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"58.3","Single Cell Type RNA - T-cells [nTPM]":"6.9","Single Cell Type RNA - Theca cells [nTPM]":"6.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.4","Single Cell Type RNA - Urothelial cells [nTPM]":"10.0"},{"Gene":"NAGLU","Gene synonym":["NAG"],"Ensembl":"ENSG00000108784","Gene description":"N-acetyl-alpha-glucosaminidase","Uniprot":["P54802"],"Chromosome":"17","Position":"42536241-42544449","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Mucopolysaccharidosis","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Theca cells":"74.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038815"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"270000000","Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038815":"AB_10697398"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.17e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.59e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.90e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.58e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Tissue RNA - adipose tissue [nTPM]":"41.6","Tissue RNA - adrenal gland [nTPM]":"37.9","Tissue RNA - amygdala [nTPM]":"12.5","Tissue RNA - appendix [nTPM]":"14.8","Tissue RNA - basal ganglia [nTPM]":"21.6","Tissue RNA - bone marrow [nTPM]":"20.3","Tissue RNA - breast [nTPM]":"35.3","Tissue RNA - cerebellum [nTPM]":"16.6","Tissue RNA - cerebral cortex [nTPM]":"16.7","Tissue RNA - cervix [nTPM]":"31.1","Tissue RNA - choroid plexus [nTPM]":"28.7","Tissue RNA - colon [nTPM]":"25.1","Tissue RNA - duodenum [nTPM]":"24.3","Tissue RNA - endometrium 1 [nTPM]":"34.7","Tissue RNA - epididymis [nTPM]":"12.8","Tissue RNA - esophagus [nTPM]":"19.5","Tissue RNA - fallopian tube [nTPM]":"27.6","Tissue RNA - gallbladder [nTPM]":"27.4","Tissue RNA - heart muscle [nTPM]":"20.1","Tissue RNA - hippocampal formation [nTPM]":"12.0","Tissue RNA - hypothalamus [nTPM]":"15.0","Tissue RNA - kidney [nTPM]":"39.3","Tissue RNA - liver [nTPM]":"59.3","Tissue RNA - lung [nTPM]":"30.8","Tissue RNA - lymph node [nTPM]":"24.0","Tissue RNA - medulla oblongata [nTPM]":"18.0","Tissue RNA - midbrain [nTPM]":"19.2","Tissue RNA - ovary [nTPM]":"35.2","Tissue RNA - pancreas [nTPM]":"63.8","Tissue RNA - parathyroid gland [nTPM]":"21.3","Tissue RNA - pituitary gland [nTPM]":"22.5","Tissue RNA - placenta [nTPM]":"26.1","Tissue RNA - pons [nTPM]":"20.1","Tissue RNA - prostate [nTPM]":"28.3","Tissue RNA - rectum [nTPM]":"16.4","Tissue RNA - retina [nTPM]":"3.1","Tissue RNA - salivary gland [nTPM]":"37.7","Tissue RNA - seminal vesicle [nTPM]":"18.4","Tissue RNA - skeletal muscle [nTPM]":"16.0","Tissue RNA - skin 1 [nTPM]":"25.1","Tissue RNA - small intestine [nTPM]":"30.9","Tissue RNA - smooth muscle [nTPM]":"13.8","Tissue RNA - spinal cord [nTPM]":"14.2","Tissue RNA - spleen [nTPM]":"40.7","Tissue RNA - stomach 1 [nTPM]":"35.1","Tissue RNA - testis [nTPM]":"8.7","Tissue RNA - thalamus [nTPM]":"19.5","Tissue RNA - thymus [nTPM]":"17.1","Tissue RNA - thyroid gland [nTPM]":"37.6","Tissue RNA - tongue [nTPM]":"9.7","Tissue RNA - tonsil [nTPM]":"13.4","Tissue RNA - urinary bladder [nTPM]":"28.9","Tissue RNA - vagina [nTPM]":"23.9","Tissue RNA - white matter [nTPM]":"30.0","Cell RNA - A-431 [nTPM]":"16.0","Cell RNA - A549 [nTPM]":"55.3","Cell RNA - AF22 [nTPM]":"10.8","Cell RNA - AN3-CA [nTPM]":"24.6","Cell RNA - ASC diff [nTPM]":"106.6","Cell RNA - ASC TERT1 [nTPM]":"34.5","Cell RNA - BEWO [nTPM]":"36.4","Cell RNA - BJ [nTPM]":"24.0","Cell RNA - BJ hTERT+ [nTPM]":"56.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"31.7","Cell RNA - CACO-2 [nTPM]":"14.9","Cell RNA - CAPAN-2 [nTPM]":"40.4","Cell RNA - Daudi [nTPM]":"20.3","Cell RNA - EFO-21 [nTPM]":"23.7","Cell RNA - fHDF\/TERT166 [nTPM]":"37.4","Cell RNA - GAMG [nTPM]":"54.7","Cell RNA - HaCaT [nTPM]":"38.3","Cell RNA - HAP1 [nTPM]":"9.7","Cell RNA - HBEC3-KT [nTPM]":"11.7","Cell RNA - HBF TERT88 [nTPM]":"5.5","Cell RNA - HDLM-2 [nTPM]":"15.8","Cell RNA - HEK 293 [nTPM]":"20.2","Cell RNA - HEL [nTPM]":"11.2","Cell RNA - HeLa [nTPM]":"31.3","Cell RNA - Hep G2 [nTPM]":"31.8","Cell RNA - HHSteC [nTPM]":"35.3","Cell RNA - HL-60 [nTPM]":"13.3","Cell RNA - HMC-1 [nTPM]":"27.7","Cell RNA - HSkMC [nTPM]":"41.4","Cell RNA - hTCEpi [nTPM]":"17.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.6","Cell RNA - hTERT-HME1 [nTPM]":"16.9","Cell RNA - hTERT-RPE1 [nTPM]":"27.3","Cell RNA - HUVEC TERT2 [nTPM]":"32.8","Cell RNA - JURKAT [nTPM]":"3.6","Cell RNA - K-562 [nTPM]":"16.6","Cell RNA - Karpas-707 [nTPM]":"39.3","Cell RNA - LHCN-M2 [nTPM]":"27.9","Cell RNA - MCF7 [nTPM]":"38.9","Cell RNA - MOLT-4 [nTPM]":"2.2","Cell RNA - NB-4 [nTPM]":"23.0","Cell RNA - NTERA-2 [nTPM]":"12.6","Cell RNA - OE19 [nTPM]":"34.6","Cell RNA - PC-3 [nTPM]":"7.0","Cell RNA - REH [nTPM]":"8.7","Cell RNA - RH-30 [nTPM]":"23.6","Cell RNA - RPMI-8226 [nTPM]":"47.2","Cell RNA - RPTEC TERT1 [nTPM]":"33.1","Cell RNA - RT4 [nTPM]":"36.1","Cell RNA - SCLC-21H [nTPM]":"16.2","Cell RNA - SH-SY5Y [nTPM]":"24.4","Cell RNA - SiHa [nTPM]":"12.9","Cell RNA - SK-BR-3 [nTPM]":"17.6","Cell RNA - SK-MEL-30 [nTPM]":"20.4","Cell RNA - SuSa [nTPM]":"15.6","Cell RNA - T-47d [nTPM]":"82.1","Cell RNA - THP-1 [nTPM]":"14.1","Cell RNA - TIME [nTPM]":"25.8","Cell RNA - U-138 MG [nTPM]":"59.3","Cell RNA - U-2 OS [nTPM]":"9.7","Cell RNA - U-2197 [nTPM]":"23.8","Cell RNA - U-251 MG [nTPM]":"15.7","Cell RNA - U-266\/70 [nTPM]":"52.6","Cell RNA - U-266\/84 [nTPM]":"25.8","Cell RNA - U-698 [nTPM]":"17.6","Cell RNA - U-87 MG [nTPM]":"35.9","Cell RNA - U-937 [nTPM]":"14.4","Cell RNA - WM-115 [nTPM]":"43.1","Blood RNA - basophil [nTPM]":"1.1","Blood RNA - classical monocyte [nTPM]":"2.4","Blood RNA - eosinophil [nTPM]":"1.9","Blood RNA - gdT-cell [nTPM]":"2.5","Blood RNA - intermediate monocyte [nTPM]":"1.8","Blood RNA - MAIT T-cell [nTPM]":"2.4","Blood RNA - memory B-cell [nTPM]":"2.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.0","Blood RNA - memory CD8 T-cell [nTPM]":"1.3","Blood RNA - myeloid DC [nTPM]":"2.1","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"1.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.4","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"2.1","Blood RNA - non-classical monocyte [nTPM]":"2.9","Blood RNA - plasmacytoid DC [nTPM]":"2.8","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"12.5","Brain RNA - basal ganglia [nTPM]":"21.6","Brain RNA - cerebellum [nTPM]":"16.6","Brain RNA - cerebral cortex [nTPM]":"16.7","Brain RNA - hippocampal formation [nTPM]":"12.0","Brain RNA - hypothalamus [nTPM]":"15.0","Brain RNA - medulla oblongata [nTPM]":"18.0","Brain RNA - midbrain [nTPM]":"19.2","Brain RNA - pons [nTPM]":"20.1","Brain RNA - spinal cord [nTPM]":"14.2","Brain RNA - thalamus [nTPM]":"19.5","Brain RNA - white matter [nTPM]":"30.0","Single Cell Type RNA - Adipocytes [nTPM]":"14.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.8","Single Cell Type RNA - Astrocytes [nTPM]":"17.3","Single Cell Type RNA - B-cells [nTPM]":"9.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"15.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"4.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.8","Single Cell Type RNA - dendritic cells [nTPM]":"11.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"21.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"18.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.5","Single Cell Type RNA - Endothelial cells [nTPM]":"12.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"4.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"33.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.5","Single Cell Type RNA - Fibroblasts [nTPM]":"26.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"27.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.1","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"40.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"24.3","Single Cell Type RNA - Hepatocytes [nTPM]":"43.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"37.6","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"26.0","Single Cell Type RNA - Langerhans cells [nTPM]":"3.5","Single Cell Type RNA - Late spermatids [nTPM]":"2.4","Single Cell Type RNA - Leydig cells [nTPM]":"19.9","Single Cell Type RNA - Macrophages [nTPM]":"19.0","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"5.9","Single Cell Type RNA - Muller glia cells [nTPM]":"13.2","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.8","Single Cell Type RNA - Paneth cells [nTPM]":"5.4","Single Cell Type RNA - Peritubular cells [nTPM]":"12.8","Single Cell Type RNA - Plasma cells [nTPM]":"12.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"31.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"6.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"18.5","Single Cell Type RNA - T-cells [nTPM]":"6.0","Single Cell Type RNA - Theca cells [nTPM]":"74.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.0","Single Cell Type RNA - Urothelial cells [nTPM]":"6.0"},{"Gene":"NAGPA","Gene synonym":["APAA","UCE"],"Ensembl":"ENSG00000103174","Gene description":"N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase","Uniprot":["Q9UK23"],"Chromosome":"16","Position":"5024844-5034141","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"29.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"44.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"53.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064055"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7800000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA064055":"AB_2685183"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.67e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.51e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.67e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.3","Tissue RNA - adrenal gland [nTPM]":"7.0","Tissue RNA - amygdala [nTPM]":"20.3","Tissue RNA - appendix [nTPM]":"5.7","Tissue RNA - basal ganglia [nTPM]":"21.6","Tissue RNA - bone marrow [nTPM]":"6.2","Tissue RNA - breast [nTPM]":"5.5","Tissue RNA - cerebellum [nTPM]":"17.9","Tissue RNA - cerebral cortex [nTPM]":"29.6","Tissue RNA - cervix [nTPM]":"5.5","Tissue RNA - choroid plexus [nTPM]":"17.6","Tissue RNA - colon [nTPM]":"8.8","Tissue RNA - duodenum [nTPM]":"6.5","Tissue RNA - endometrium 1 [nTPM]":"6.6","Tissue RNA - epididymis [nTPM]":"2.6","Tissue RNA - esophagus [nTPM]":"6.4","Tissue RNA - fallopian tube [nTPM]":"4.8","Tissue RNA - gallbladder [nTPM]":"3.4","Tissue RNA - heart muscle [nTPM]":"5.4","Tissue RNA - hippocampal formation [nTPM]":"23.6","Tissue RNA - hypothalamus [nTPM]":"18.3","Tissue RNA - kidney [nTPM]":"8.2","Tissue RNA - liver [nTPM]":"9.0","Tissue RNA - lung [nTPM]":"5.7","Tissue RNA - lymph node [nTPM]":"6.4","Tissue RNA - medulla oblongata [nTPM]":"19.2","Tissue RNA - midbrain [nTPM]":"18.0","Tissue RNA - ovary [nTPM]":"3.6","Tissue RNA - pancreas [nTPM]":"6.2","Tissue RNA - parathyroid gland [nTPM]":"4.8","Tissue RNA - pituitary gland [nTPM]":"5.4","Tissue RNA - placenta [nTPM]":"4.1","Tissue RNA - pons [nTPM]":"18.5","Tissue RNA - prostate [nTPM]":"5.7","Tissue RNA - rectum [nTPM]":"3.0","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"5.4","Tissue RNA - seminal vesicle [nTPM]":"3.3","Tissue RNA - skeletal muscle [nTPM]":"6.1","Tissue RNA - skin 1 [nTPM]":"6.7","Tissue RNA - small intestine [nTPM]":"9.8","Tissue RNA - smooth muscle [nTPM]":"3.4","Tissue RNA - spinal cord [nTPM]":"17.8","Tissue RNA - spleen [nTPM]":"11.8","Tissue RNA - stomach 1 [nTPM]":"9.4","Tissue RNA - testis [nTPM]":"3.3","Tissue RNA - thalamus [nTPM]":"19.6","Tissue RNA - thymus [nTPM]":"3.5","Tissue RNA - thyroid gland [nTPM]":"5.7","Tissue RNA - tongue [nTPM]":"2.4","Tissue RNA - tonsil [nTPM]":"2.8","Tissue RNA - urinary bladder [nTPM]":"6.4","Tissue RNA - vagina [nTPM]":"5.1","Tissue RNA - white matter [nTPM]":"20.9","Cell RNA - A-431 [nTPM]":"2.5","Cell RNA - A549 [nTPM]":"9.7","Cell RNA - AF22 [nTPM]":"1.6","Cell RNA - AN3-CA [nTPM]":"10.4","Cell RNA - ASC diff [nTPM]":"4.0","Cell RNA - ASC TERT1 [nTPM]":"5.0","Cell RNA - BEWO [nTPM]":"10.8","Cell RNA - BJ [nTPM]":"7.1","Cell RNA - BJ hTERT+ [nTPM]":"12.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.2","Cell RNA - CACO-2 [nTPM]":"8.0","Cell RNA - CAPAN-2 [nTPM]":"19.9","Cell RNA - Daudi [nTPM]":"1.0","Cell RNA - EFO-21 [nTPM]":"8.8","Cell RNA - fHDF\/TERT166 [nTPM]":"9.6","Cell RNA - GAMG [nTPM]":"15.8","Cell RNA - HaCaT [nTPM]":"7.3","Cell RNA - HAP1 [nTPM]":"4.4","Cell RNA - HBEC3-KT [nTPM]":"7.8","Cell RNA - HBF TERT88 [nTPM]":"2.6","Cell RNA - HDLM-2 [nTPM]":"11.8","Cell RNA - HEK 293 [nTPM]":"13.3","Cell RNA - HEL [nTPM]":"3.6","Cell RNA - HeLa [nTPM]":"5.7","Cell RNA - Hep G2 [nTPM]":"53.1","Cell RNA - HHSteC [nTPM]":"12.7","Cell RNA - HL-60 [nTPM]":"8.8","Cell RNA - HMC-1 [nTPM]":"14.6","Cell RNA - HSkMC [nTPM]":"7.7","Cell RNA - hTCEpi [nTPM]":"8.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.0","Cell RNA - hTERT-HME1 [nTPM]":"2.7","Cell RNA - hTERT-RPE1 [nTPM]":"11.0","Cell RNA - HUVEC TERT2 [nTPM]":"14.6","Cell RNA - JURKAT [nTPM]":"8.8","Cell RNA - K-562 [nTPM]":"11.5","Cell RNA - Karpas-707 [nTPM]":"14.1","Cell RNA - LHCN-M2 [nTPM]":"5.5","Cell RNA - MCF7 [nTPM]":"11.3","Cell RNA - MOLT-4 [nTPM]":"4.0","Cell RNA - NB-4 [nTPM]":"23.6","Cell RNA - NTERA-2 [nTPM]":"5.0","Cell RNA - OE19 [nTPM]":"6.3","Cell RNA - PC-3 [nTPM]":"10.2","Cell RNA - REH [nTPM]":"10.4","Cell RNA - RH-30 [nTPM]":"3.7","Cell RNA - RPMI-8226 [nTPM]":"19.3","Cell RNA - RPTEC TERT1 [nTPM]":"5.8","Cell RNA - RT4 [nTPM]":"3.9","Cell RNA - SCLC-21H [nTPM]":"4.0","Cell RNA - SH-SY5Y [nTPM]":"5.6","Cell RNA - SiHa [nTPM]":"5.6","Cell RNA - SK-BR-3 [nTPM]":"14.2","Cell RNA - SK-MEL-30 [nTPM]":"15.1","Cell RNA - SuSa [nTPM]":"1.4","Cell RNA - T-47d [nTPM]":"9.7","Cell RNA - THP-1 [nTPM]":"10.5","Cell RNA - TIME [nTPM]":"11.0","Cell RNA - U-138 MG [nTPM]":"9.9","Cell RNA - U-2 OS [nTPM]":"7.2","Cell RNA - U-2197 [nTPM]":"24.0","Cell RNA - U-251 MG [nTPM]":"5.3","Cell RNA - U-266\/70 [nTPM]":"6.9","Cell RNA - U-266\/84 [nTPM]":"6.3","Cell RNA - U-698 [nTPM]":"2.3","Cell RNA - U-87 MG [nTPM]":"4.6","Cell RNA - U-937 [nTPM]":"13.1","Cell RNA - WM-115 [nTPM]":"8.3","Blood RNA - basophil [nTPM]":"3.9","Blood RNA - classical monocyte [nTPM]":"39.3","Blood RNA - eosinophil [nTPM]":"10.4","Blood RNA - gdT-cell [nTPM]":"17.9","Blood RNA - intermediate monocyte [nTPM]":"35.0","Blood RNA - MAIT T-cell [nTPM]":"14.2","Blood RNA - memory B-cell [nTPM]":"17.3","Blood RNA - memory CD4 T-cell [nTPM]":"17.1","Blood RNA - memory CD8 T-cell [nTPM]":"15.4","Blood RNA - myeloid DC [nTPM]":"50.5","Blood RNA - naive B-cell [nTPM]":"14.2","Blood RNA - naive CD4 T-cell [nTPM]":"14.0","Blood RNA - naive CD8 T-cell [nTPM]":"13.2","Blood RNA - neutrophil [nTPM]":"1.2","Blood RNA - NK-cell [nTPM]":"10.6","Blood RNA - non-classical monocyte [nTPM]":"23.6","Blood RNA - plasmacytoid DC [nTPM]":"12.9","Blood RNA - T-reg [nTPM]":"16.3","Blood RNA - total PBMC [nTPM]":"20.1","Brain RNA - amygdala [nTPM]":"20.3","Brain RNA - basal ganglia [nTPM]":"21.6","Brain RNA - cerebellum [nTPM]":"17.9","Brain RNA - cerebral cortex [nTPM]":"29.6","Brain RNA - hippocampal formation [nTPM]":"23.6","Brain RNA - hypothalamus [nTPM]":"18.3","Brain RNA - medulla oblongata [nTPM]":"19.2","Brain RNA - midbrain [nTPM]":"18.0","Brain RNA - pons [nTPM]":"18.5","Brain RNA - spinal cord [nTPM]":"17.8","Brain RNA - thalamus [nTPM]":"19.6","Brain RNA - white matter [nTPM]":"20.9","Single Cell Type RNA - Adipocytes [nTPM]":"8.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.7","Single Cell Type RNA - Astrocytes [nTPM]":"7.8","Single Cell Type RNA - B-cells [nTPM]":"15.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"14.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"4.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.3","Single Cell Type RNA - dendritic cells [nTPM]":"10.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"21.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.7","Single Cell Type RNA - Endothelial cells [nTPM]":"8.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"9.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"44.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.9","Single Cell Type RNA - Fibroblasts [nTPM]":"4.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"28.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"8.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.7","Single Cell Type RNA - Hepatocytes [nTPM]":"7.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"27.2","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.6","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"24.9","Single Cell Type RNA - Langerhans cells [nTPM]":"8.6","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"20.6","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"24.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.5","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.5","Single Cell Type RNA - Paneth cells [nTPM]":"18.4","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"13.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"28.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.8","Single Cell Type RNA - Spermatocytes [nTPM]":"4.4","Single Cell Type RNA - Spermatogonia [nTPM]":"8.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.4","Single Cell Type RNA - T-cells [nTPM]":"12.1","Single Cell Type RNA - Theca cells [nTPM]":"5.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.4","Single Cell Type RNA - Urothelial cells [nTPM]":"3.2"},{"Gene":"NAGS","Gene synonym":["AGAS","ARGA","NAT7"],"Ensembl":"ENSG00000161653","Gene description":"N-acetylglutamate synthase","Uniprot":["Q8N159"],"Chromosome":"17","Position":"44004622-44009068","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Urea cycle"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"intestine":"15.9","liver":"48.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"21.7","Proximal enterocytes":"44.2","Proximal tubular cells":"20.7","Spermatocytes":"16.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"12.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC TERT1":"5.5","HHSteC":"5.2","TIME":"7.1","U-87 MG":"10.0"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027300"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA027300":"AB_2672207"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.9","Tissue RNA - adrenal gland [nTPM]":"0.7","Tissue RNA - amygdala [nTPM]":"2.0","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"1.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.4","Tissue RNA - cerebellum [nTPM]":"0.9","Tissue RNA - cerebral cortex [nTPM]":"2.0","Tissue RNA - cervix [nTPM]":"0.8","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"2.4","Tissue RNA - duodenum [nTPM]":"15.9","Tissue RNA - endometrium 1 [nTPM]":"0.8","Tissue RNA - epididymis [nTPM]":"1.8","Tissue RNA - esophagus [nTPM]":"1.4","Tissue RNA - fallopian tube [nTPM]":"0.7","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"1.2","Tissue RNA - hippocampal formation [nTPM]":"1.0","Tissue RNA - hypothalamus [nTPM]":"3.5","Tissue RNA - kidney [nTPM]":"4.9","Tissue RNA - liver [nTPM]":"48.2","Tissue RNA - lung [nTPM]":"1.9","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"2.0","Tissue RNA - midbrain [nTPM]":"1.4","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"3.3","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"2.2","Tissue RNA - prostate [nTPM]":"1.1","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"1.0","Tissue RNA - seminal vesicle [nTPM]":"1.4","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"1.0","Tissue RNA - small intestine [nTPM]":"13.6","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"1.3","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"3.6","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"4.4","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"1.0","Tissue RNA - white matter [nTPM]":"1.0","Cell RNA - A-431 [nTPM]":"2.9","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"5.5","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.5","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"1.7","Cell RNA - CAPAN-2 [nTPM]":"0.7","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"1.3","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"1.5","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.7","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"2.2","Cell RNA - HHSteC [nTPM]":"5.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"3.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.7","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.6","Cell RNA - HUVEC TERT2 [nTPM]":"1.4","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"1.5","Cell RNA - PC-3 [nTPM]":"2.7","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"2.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.9","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"7.1","Cell RNA - U-138 MG [nTPM]":"2.5","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.6","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"10.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"0.8","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"0.9","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.8","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.5","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"2.0","Brain RNA - basal ganglia [nTPM]":"1.2","Brain RNA - cerebellum [nTPM]":"0.9","Brain RNA - cerebral cortex [nTPM]":"2.0","Brain RNA - hippocampal formation [nTPM]":"1.0","Brain RNA - hypothalamus [nTPM]":"3.5","Brain RNA - medulla oblongata [nTPM]":"2.0","Brain RNA - midbrain [nTPM]":"1.4","Brain RNA - pons [nTPM]":"2.2","Brain RNA - spinal cord [nTPM]":"1.3","Brain RNA - thalamus [nTPM]":"3.6","Brain RNA - white matter [nTPM]":"1.0","Single Cell Type RNA - Adipocytes [nTPM]":"1.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"2.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.9","Single Cell Type RNA - dendritic cells [nTPM]":"1.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.9","Single Cell Type RNA - Early spermatids [nTPM]":"5.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"2.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.9","Single Cell Type RNA - Fibroblasts [nTPM]":"0.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"21.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.8","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"5.3","Single Cell Type RNA - Late spermatids [nTPM]":"5.3","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"2.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"6.1","Single Cell Type RNA - Muller glia cells [nTPM]":"1.0","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.1","Single Cell Type RNA - Paneth cells [nTPM]":"11.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"44.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"20.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.9","Single Cell Type RNA - Spermatocytes [nTPM]":"16.0","Single Cell Type RNA - Spermatogonia [nTPM]":"2.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"1.4","Single Cell Type RNA - Theca cells [nTPM]":"0.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"NALCN","Gene synonym":["bA430M15.1","CanIon","VGCNL1"],"Ensembl":"ENSG00000102452","Gene description":"Sodium leak channel, non-selective","Uniprot":["Q8IZF0"],"Chromosome":"13","Position":"101053776-101416508","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Sodium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"13.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Astrocytes":"125.4","Excitatory neurons":"265.8","Inhibitory neurons":"277.4","Oligodendrocyte precursor cells":"324.7","Oligodendrocytes":"477.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"2.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"2.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"14.2","HHSteC":"14.4","hTERT-RPE1":"11.0","TIME":"19.8","U-87 MG":"11.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031889","HPA031890","HPA031958"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031889":"AB_10669638","HPA031890":"AB_10696056","HPA031958":"AB_10601039"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"4.3","Tissue RNA - amygdala [nTPM]":"7.5","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"9.8","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"2.7","Tissue RNA - cerebellum [nTPM]":"6.4","Tissue RNA - cerebral cortex [nTPM]":"10.3","Tissue RNA - cervix [nTPM]":"1.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.6","Tissue RNA - endometrium 1 [nTPM]":"0.5","Tissue RNA - epididymis [nTPM]":"1.5","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"1.0","Tissue RNA - gallbladder [nTPM]":"2.3","Tissue RNA - heart muscle [nTPM]":"3.3","Tissue RNA - hippocampal formation [nTPM]":"8.6","Tissue RNA - hypothalamus [nTPM]":"10.2","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"1.1","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"8.2","Tissue RNA - midbrain [nTPM]":"5.8","Tissue RNA - ovary [nTPM]":"2.8","Tissue RNA - pancreas [nTPM]":"1.3","Tissue RNA - parathyroid gland [nTPM]":"2.9","Tissue RNA - pituitary gland [nTPM]":"6.8","Tissue RNA - placenta [nTPM]":"3.0","Tissue RNA - pons [nTPM]":"7.0","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.6","Tissue RNA - retina [nTPM]":"6.1","Tissue RNA - salivary gland [nTPM]":"0.8","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"6.8","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"0.7","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"8.3","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"2.4","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.5","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"13.1","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"7.8","Cell RNA - AF22 [nTPM]":"1.4","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.7","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.8","Cell RNA - BJ hTERT+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"8.9","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"3.6","Cell RNA - GAMG [nTPM]":"0.8","Cell RNA - HaCaT [nTPM]":"14.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"2.2","Cell RNA - HBF TERT88 [nTPM]":"5.5","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.2","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"3.8","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"14.4","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.4","Cell RNA - hTCEpi [nTPM]":"0.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.7","Cell RNA - hTERT-HME1 [nTPM]":"4.6","Cell RNA - hTERT-RPE1 [nTPM]":"11.0","Cell RNA - HUVEC TERT2 [nTPM]":"8.2","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"5.9","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"1.3","Cell RNA - PC-3 [nTPM]":"1.8","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"4.6","Cell RNA - RT4 [nTPM]":"1.9","Cell RNA - SCLC-21H [nTPM]":"1.2","Cell RNA - SH-SY5Y [nTPM]":"0.6","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.8","Cell RNA - SuSa [nTPM]":"0.9","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"19.8","Cell RNA - U-138 MG [nTPM]":"0.4","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"1.8","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"11.4","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"2.6","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"7.5","Brain RNA - basal ganglia [nTPM]":"9.8","Brain RNA - cerebellum [nTPM]":"6.4","Brain RNA - cerebral cortex [nTPM]":"10.3","Brain RNA - hippocampal formation [nTPM]":"8.6","Brain RNA - hypothalamus [nTPM]":"10.2","Brain RNA - medulla oblongata [nTPM]":"8.2","Brain RNA - midbrain [nTPM]":"5.8","Brain RNA - pons [nTPM]":"7.0","Brain RNA - spinal cord [nTPM]":"6.8","Brain RNA - thalamus [nTPM]":"8.3","Brain RNA - white matter [nTPM]":"13.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"125.4","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"15.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"4.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"265.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"1.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"277.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"324.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"477.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"NANS","Gene synonym":["SAS"],"Ensembl":"ENSG00000095380","Gene description":"N-acetylneuraminate synthase","Uniprot":["Q9NR45"],"Chromosome":"9","Position":"98056732-98083077","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Dwarfism","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Intestinal goblet cells":"362.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019223"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"410000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 4: Stomach - Digestion","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA019223":"AB_1854298"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.71e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.31e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.42e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Tissue RNA - adipose tissue [nTPM]":"39.4","Tissue RNA - adrenal gland [nTPM]":"28.9","Tissue RNA - amygdala [nTPM]":"16.2","Tissue RNA - appendix [nTPM]":"49.3","Tissue RNA - basal ganglia [nTPM]":"15.0","Tissue RNA - bone marrow [nTPM]":"67.8","Tissue RNA - breast [nTPM]":"36.5","Tissue RNA - cerebellum [nTPM]":"13.8","Tissue RNA - cerebral cortex [nTPM]":"18.2","Tissue RNA - cervix [nTPM]":"49.9","Tissue RNA - choroid plexus [nTPM]":"29.8","Tissue RNA - colon [nTPM]":"133.5","Tissue RNA - duodenum [nTPM]":"52.2","Tissue RNA - endometrium 1 [nTPM]":"28.5","Tissue RNA - epididymis [nTPM]":"33.5","Tissue RNA - esophagus [nTPM]":"51.4","Tissue RNA - fallopian tube [nTPM]":"29.4","Tissue RNA - gallbladder [nTPM]":"34.2","Tissue RNA - heart muscle [nTPM]":"46.3","Tissue RNA - hippocampal formation [nTPM]":"15.1","Tissue RNA - hypothalamus [nTPM]":"17.0","Tissue RNA - kidney [nTPM]":"32.8","Tissue RNA - liver [nTPM]":"67.0","Tissue RNA - lung [nTPM]":"45.9","Tissue RNA - lymph node [nTPM]":"59.5","Tissue RNA - medulla oblongata [nTPM]":"16.2","Tissue RNA - midbrain [nTPM]":"17.2","Tissue RNA - ovary [nTPM]":"26.2","Tissue RNA - pancreas [nTPM]":"67.6","Tissue RNA - parathyroid gland [nTPM]":"20.4","Tissue RNA - pituitary gland [nTPM]":"42.5","Tissue RNA - placenta [nTPM]":"31.7","Tissue RNA - pons [nTPM]":"18.4","Tissue RNA - prostate [nTPM]":"106.4","Tissue RNA - rectum [nTPM]":"129.2","Tissue RNA - retina [nTPM]":"8.3","Tissue RNA - salivary gland [nTPM]":"120.0","Tissue RNA - seminal vesicle [nTPM]":"19.7","Tissue RNA - skeletal muscle [nTPM]":"34.2","Tissue RNA - skin 1 [nTPM]":"29.2","Tissue RNA - small intestine [nTPM]":"47.8","Tissue RNA - smooth muscle [nTPM]":"29.0","Tissue RNA - spinal cord [nTPM]":"15.1","Tissue RNA - spleen [nTPM]":"53.3","Tissue RNA - stomach 1 [nTPM]":"76.1","Tissue RNA - testis [nTPM]":"27.2","Tissue RNA - thalamus [nTPM]":"17.2","Tissue RNA - thymus [nTPM]":"18.8","Tissue RNA - thyroid gland [nTPM]":"27.3","Tissue RNA - tongue [nTPM]":"17.4","Tissue RNA - tonsil [nTPM]":"60.5","Tissue RNA - urinary bladder [nTPM]":"47.5","Tissue RNA - vagina [nTPM]":"41.5","Tissue RNA - white matter [nTPM]":"17.2","Cell RNA - A-431 [nTPM]":"387.9","Cell RNA - A549 [nTPM]":"111.8","Cell RNA - AF22 [nTPM]":"32.5","Cell RNA - AN3-CA [nTPM]":"94.5","Cell RNA - ASC diff [nTPM]":"64.0","Cell RNA - ASC TERT1 [nTPM]":"68.8","Cell RNA - BEWO [nTPM]":"70.5","Cell RNA - BJ [nTPM]":"120.9","Cell RNA - BJ hTERT+ [nTPM]":"93.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"96.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"78.3","Cell RNA - CACO-2 [nTPM]":"134.8","Cell RNA - CAPAN-2 [nTPM]":"53.6","Cell RNA - Daudi [nTPM]":"118.1","Cell RNA - EFO-21 [nTPM]":"57.2","Cell RNA - fHDF\/TERT166 [nTPM]":"133.3","Cell RNA - GAMG [nTPM]":"101.9","Cell RNA - HaCaT [nTPM]":"134.1","Cell RNA - HAP1 [nTPM]":"61.0","Cell RNA - HBEC3-KT [nTPM]":"103.6","Cell RNA - HBF TERT88 [nTPM]":"80.0","Cell RNA - HDLM-2 [nTPM]":"95.7","Cell RNA - HEK 293 [nTPM]":"91.0","Cell RNA - HEL [nTPM]":"70.3","Cell RNA - HeLa [nTPM]":"128.4","Cell RNA - Hep G2 [nTPM]":"271.9","Cell RNA - HHSteC [nTPM]":"176.3","Cell RNA - HL-60 [nTPM]":"80.3","Cell RNA - HMC-1 [nTPM]":"55.3","Cell RNA - HSkMC [nTPM]":"58.4","Cell RNA - hTCEpi [nTPM]":"69.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"102.9","Cell RNA - hTERT-HME1 [nTPM]":"116.4","Cell RNA - hTERT-RPE1 [nTPM]":"111.8","Cell RNA - HUVEC TERT2 [nTPM]":"104.3","Cell RNA - JURKAT [nTPM]":"57.9","Cell RNA - K-562 [nTPM]":"129.9","Cell RNA - Karpas-707 [nTPM]":"119.8","Cell RNA - LHCN-M2 [nTPM]":"71.2","Cell RNA - MCF7 [nTPM]":"265.0","Cell RNA - MOLT-4 [nTPM]":"54.1","Cell RNA - NB-4 [nTPM]":"114.9","Cell RNA - NTERA-2 [nTPM]":"56.2","Cell RNA - OE19 [nTPM]":"277.5","Cell RNA - PC-3 [nTPM]":"143.3","Cell RNA - REH [nTPM]":"103.4","Cell RNA - RH-30 [nTPM]":"89.0","Cell RNA - RPMI-8226 [nTPM]":"121.5","Cell RNA - RPTEC TERT1 [nTPM]":"78.2","Cell RNA - RT4 [nTPM]":"116.6","Cell RNA - SCLC-21H [nTPM]":"65.7","Cell RNA - SH-SY5Y [nTPM]":"34.4","Cell RNA - SiHa [nTPM]":"77.8","Cell RNA - SK-BR-3 [nTPM]":"414.4","Cell RNA - SK-MEL-30 [nTPM]":"107.2","Cell RNA - SuSa [nTPM]":"35.8","Cell RNA - T-47d [nTPM]":"137.6","Cell RNA - THP-1 [nTPM]":"85.3","Cell RNA - TIME [nTPM]":"274.2","Cell RNA - U-138 MG [nTPM]":"74.8","Cell RNA - U-2 OS [nTPM]":"72.5","Cell RNA - U-2197 [nTPM]":"193.4","Cell RNA - U-251 MG [nTPM]":"125.8","Cell RNA - U-266\/70 [nTPM]":"110.7","Cell RNA - U-266\/84 [nTPM]":"99.3","Cell RNA - U-698 [nTPM]":"45.7","Cell RNA - U-87 MG [nTPM]":"88.4","Cell RNA - U-937 [nTPM]":"95.9","Cell RNA - WM-115 [nTPM]":"59.6","Blood RNA - basophil [nTPM]":"30.9","Blood RNA - classical monocyte [nTPM]":"190.9","Blood RNA - eosinophil [nTPM]":"29.5","Blood RNA - gdT-cell [nTPM]":"34.9","Blood RNA - intermediate monocyte [nTPM]":"237.6","Blood RNA - MAIT T-cell [nTPM]":"53.4","Blood RNA - memory B-cell [nTPM]":"55.6","Blood RNA - memory CD4 T-cell [nTPM]":"45.5","Blood RNA - memory CD8 T-cell [nTPM]":"36.8","Blood RNA - myeloid DC [nTPM]":"194.7","Blood RNA - naive B-cell [nTPM]":"54.9","Blood RNA - naive CD4 T-cell [nTPM]":"48.8","Blood RNA - naive CD8 T-cell [nTPM]":"33.7","Blood RNA - neutrophil [nTPM]":"77.4","Blood RNA - NK-cell [nTPM]":"38.9","Blood RNA - non-classical monocyte [nTPM]":"217.0","Blood RNA - plasmacytoid DC [nTPM]":"178.8","Blood RNA - T-reg [nTPM]":"58.3","Blood RNA - total PBMC [nTPM]":"91.4","Brain RNA - amygdala [nTPM]":"16.2","Brain RNA - basal ganglia [nTPM]":"15.0","Brain RNA - cerebellum [nTPM]":"13.8","Brain RNA - cerebral cortex [nTPM]":"18.2","Brain RNA - hippocampal formation [nTPM]":"15.1","Brain RNA - hypothalamus [nTPM]":"17.0","Brain RNA - medulla oblongata [nTPM]":"16.2","Brain RNA - midbrain [nTPM]":"17.2","Brain RNA - pons [nTPM]":"18.4","Brain RNA - spinal cord [nTPM]":"15.1","Brain RNA - thalamus [nTPM]":"17.2","Brain RNA - white matter [nTPM]":"17.2","Single Cell Type RNA - Adipocytes [nTPM]":"46.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"54.9","Single Cell Type RNA - Astrocytes [nTPM]":"3.6","Single Cell Type RNA - B-cells [nTPM]":"57.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"70.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"134.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"183.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"30.7","Single Cell Type RNA - Bipolar cells [nTPM]":"11.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"61.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"45.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"42.9","Single Cell Type RNA - Club cells [nTPM]":"206.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"86.7","Single Cell Type RNA - dendritic cells [nTPM]":"50.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"234.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"70.5","Single Cell Type RNA - Ductal cells [nTPM]":"49.4","Single Cell Type RNA - Early spermatids [nTPM]":"42.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"63.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"37.9","Single Cell Type RNA - Endothelial cells [nTPM]":"63.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"64.9","Single Cell Type RNA - Erythroid cells [nTPM]":"18.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"100.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"159.2","Single Cell Type RNA - Fibroblasts [nTPM]":"50.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"99.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"55.8","Single Cell Type RNA - granulocytes [nTPM]":"43.8","Single Cell Type RNA - Granulosa cells [nTPM]":"29.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"34.2","Single Cell Type RNA - Hepatocytes [nTPM]":"33.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"160.0","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"362.7","Single Cell Type RNA - Ionocytes [nTPM]":"95.6","Single Cell Type RNA - Kupffer cells [nTPM]":"67.7","Single Cell Type RNA - Langerhans cells [nTPM]":"107.6","Single Cell Type RNA - Late spermatids [nTPM]":"71.5","Single Cell Type RNA - Leydig cells [nTPM]":"32.3","Single Cell Type RNA - Macrophages [nTPM]":"89.8","Single Cell Type RNA - Melanocytes [nTPM]":"129.9","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"53.1","Single Cell Type RNA - Muller glia cells [nTPM]":"14.1","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"70.9","Single Cell Type RNA - Paneth cells [nTPM]":"181.0","Single Cell Type RNA - Peritubular cells [nTPM]":"26.4","Single Cell Type RNA - Plasma cells [nTPM]":"141.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"213.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"66.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"68.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"204.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"32.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"91.3","Single Cell Type RNA - Spermatocytes [nTPM]":"10.5","Single Cell Type RNA - Spermatogonia [nTPM]":"21.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"42.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"61.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"150.8","Single Cell Type RNA - T-cells [nTPM]":"50.6","Single Cell Type RNA - Theca cells [nTPM]":"44.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"260.1","Single Cell Type RNA - Urothelial cells [nTPM]":"223.3"},{"Gene":"NARS2","Gene synonym":["DFNB94","FLJ23441","SLM5"],"Ensembl":"ENSG00000137513","Gene description":"Asparaginyl-tRNA synthetase 2, mitochondrial","Uniprot":["Q96I59"],"Chromosome":"11","Position":"78435968-78574874","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Deafness","Disease variant","Leigh syndrome","Non-syndromic deafness","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026793"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA026793":"AB_1848833"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.73e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.39e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.22e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.3","Tissue RNA - adrenal gland [nTPM]":"11.9","Tissue RNA - amygdala [nTPM]":"10.7","Tissue RNA - appendix [nTPM]":"6.8","Tissue RNA - basal ganglia [nTPM]":"12.3","Tissue RNA - bone marrow [nTPM]":"6.2","Tissue RNA - breast [nTPM]":"11.1","Tissue RNA - cerebellum [nTPM]":"12.4","Tissue RNA - cerebral cortex [nTPM]":"13.3","Tissue RNA - cervix [nTPM]":"9.6","Tissue RNA - choroid plexus [nTPM]":"19.8","Tissue RNA - colon [nTPM]":"11.3","Tissue RNA - duodenum [nTPM]":"10.3","Tissue RNA - endometrium 1 [nTPM]":"9.1","Tissue RNA - epididymis [nTPM]":"11.2","Tissue RNA - esophagus [nTPM]":"8.1","Tissue RNA - fallopian tube [nTPM]":"9.9","Tissue RNA - gallbladder [nTPM]":"7.0","Tissue RNA - heart muscle [nTPM]":"11.7","Tissue RNA - hippocampal formation [nTPM]":"10.4","Tissue RNA - hypothalamus [nTPM]":"11.7","Tissue RNA - kidney [nTPM]":"19.0","Tissue RNA - liver [nTPM]":"23.5","Tissue RNA - lung [nTPM]":"7.6","Tissue RNA - lymph node [nTPM]":"9.6","Tissue RNA - medulla oblongata [nTPM]":"11.7","Tissue RNA - midbrain [nTPM]":"13.9","Tissue RNA - ovary [nTPM]":"11.4","Tissue RNA - pancreas [nTPM]":"10.6","Tissue RNA - parathyroid gland [nTPM]":"11.4","Tissue RNA - pituitary gland [nTPM]":"7.6","Tissue RNA - placenta [nTPM]":"8.0","Tissue RNA - pons [nTPM]":"13.1","Tissue RNA - prostate [nTPM]":"10.8","Tissue RNA - rectum [nTPM]":"10.9","Tissue RNA - retina [nTPM]":"13.4","Tissue RNA - salivary gland [nTPM]":"10.7","Tissue RNA - seminal vesicle [nTPM]":"7.3","Tissue RNA - skeletal muscle [nTPM]":"23.5","Tissue RNA - skin 1 [nTPM]":"7.2","Tissue RNA - small intestine [nTPM]":"9.7","Tissue RNA - smooth muscle [nTPM]":"7.4","Tissue RNA - spinal cord [nTPM]":"11.3","Tissue RNA - spleen [nTPM]":"7.4","Tissue RNA - stomach 1 [nTPM]":"9.9","Tissue RNA - testis [nTPM]":"7.5","Tissue RNA - thalamus [nTPM]":"11.4","Tissue RNA - thymus [nTPM]":"11.7","Tissue RNA - thyroid gland [nTPM]":"11.5","Tissue RNA - tongue [nTPM]":"19.6","Tissue RNA - tonsil [nTPM]":"9.7","Tissue RNA - urinary bladder [nTPM]":"8.7","Tissue RNA - vagina [nTPM]":"8.1","Tissue RNA - white matter [nTPM]":"12.3","Cell RNA - A-431 [nTPM]":"16.7","Cell RNA - A549 [nTPM]":"22.8","Cell RNA - AF22 [nTPM]":"23.5","Cell RNA - AN3-CA [nTPM]":"15.4","Cell RNA - ASC diff [nTPM]":"16.1","Cell RNA - ASC TERT1 [nTPM]":"13.5","Cell RNA - BEWO [nTPM]":"19.5","Cell RNA - BJ [nTPM]":"13.5","Cell RNA - BJ hTERT+ [nTPM]":"13.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.9","Cell RNA - CACO-2 [nTPM]":"39.4","Cell RNA - CAPAN-2 [nTPM]":"17.4","Cell RNA - Daudi [nTPM]":"40.9","Cell RNA - EFO-21 [nTPM]":"34.1","Cell RNA - fHDF\/TERT166 [nTPM]":"8.7","Cell RNA - GAMG [nTPM]":"19.8","Cell RNA - HaCaT [nTPM]":"21.5","Cell RNA - HAP1 [nTPM]":"39.9","Cell RNA - HBEC3-KT [nTPM]":"26.3","Cell RNA - HBF TERT88 [nTPM]":"28.3","Cell RNA - HDLM-2 [nTPM]":"27.0","Cell RNA - HEK 293 [nTPM]":"21.3","Cell RNA - HEL [nTPM]":"28.9","Cell RNA - HeLa [nTPM]":"17.3","Cell RNA - Hep G2 [nTPM]":"33.7","Cell RNA - HHSteC [nTPM]":"13.3","Cell RNA - HL-60 [nTPM]":"31.3","Cell RNA - HMC-1 [nTPM]":"10.1","Cell RNA - HSkMC [nTPM]":"9.4","Cell RNA - hTCEpi [nTPM]":"16.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.1","Cell RNA - hTERT-HME1 [nTPM]":"32.0","Cell RNA - hTERT-RPE1 [nTPM]":"18.3","Cell RNA - HUVEC TERT2 [nTPM]":"17.9","Cell RNA - JURKAT [nTPM]":"33.7","Cell RNA - K-562 [nTPM]":"44.5","Cell RNA - Karpas-707 [nTPM]":"11.0","Cell RNA - LHCN-M2 [nTPM]":"23.1","Cell RNA - MCF7 [nTPM]":"19.4","Cell RNA - MOLT-4 [nTPM]":"32.7","Cell RNA - NB-4 [nTPM]":"50.3","Cell RNA - NTERA-2 [nTPM]":"25.6","Cell RNA - OE19 [nTPM]":"67.3","Cell RNA - PC-3 [nTPM]":"27.3","Cell RNA - REH [nTPM]":"33.6","Cell RNA - RH-30 [nTPM]":"38.2","Cell RNA - RPMI-8226 [nTPM]":"55.5","Cell RNA - RPTEC TERT1 [nTPM]":"27.2","Cell RNA - RT4 [nTPM]":"23.0","Cell RNA - SCLC-21H [nTPM]":"27.8","Cell RNA - SH-SY5Y [nTPM]":"17.5","Cell RNA - SiHa [nTPM]":"20.1","Cell RNA - SK-BR-3 [nTPM]":"25.4","Cell RNA - SK-MEL-30 [nTPM]":"35.5","Cell RNA - SuSa [nTPM]":"25.1","Cell RNA - T-47d [nTPM]":"24.1","Cell RNA - THP-1 [nTPM]":"12.3","Cell RNA - TIME [nTPM]":"10.9","Cell RNA - U-138 MG [nTPM]":"27.7","Cell RNA - U-2 OS [nTPM]":"32.8","Cell RNA - U-2197 [nTPM]":"32.0","Cell RNA - U-251 MG [nTPM]":"23.1","Cell RNA - U-266\/70 [nTPM]":"18.1","Cell RNA - U-266\/84 [nTPM]":"33.1","Cell RNA - U-698 [nTPM]":"91.1","Cell RNA - U-87 MG [nTPM]":"5.4","Cell RNA - U-937 [nTPM]":"27.7","Cell RNA - WM-115 [nTPM]":"19.2","Blood RNA - basophil [nTPM]":"9.5","Blood RNA - classical monocyte [nTPM]":"9.3","Blood RNA - eosinophil [nTPM]":"4.4","Blood RNA - gdT-cell [nTPM]":"11.1","Blood RNA - intermediate monocyte [nTPM]":"10.4","Blood RNA - MAIT T-cell [nTPM]":"13.8","Blood RNA - memory B-cell [nTPM]":"17.6","Blood RNA - memory CD4 T-cell [nTPM]":"12.8","Blood RNA - memory CD8 T-cell [nTPM]":"12.5","Blood RNA - myeloid DC [nTPM]":"16.6","Blood RNA - naive B-cell [nTPM]":"15.0","Blood RNA - naive CD4 T-cell [nTPM]":"18.5","Blood RNA - naive CD8 T-cell [nTPM]":"16.7","Blood RNA - neutrophil [nTPM]":"2.0","Blood RNA - NK-cell [nTPM]":"20.3","Blood RNA - non-classical monocyte [nTPM]":"12.8","Blood RNA - plasmacytoid DC [nTPM]":"12.7","Blood RNA - T-reg [nTPM]":"10.5","Blood RNA - total PBMC [nTPM]":"10.3","Brain RNA - amygdala [nTPM]":"10.7","Brain RNA - basal ganglia [nTPM]":"12.3","Brain RNA - cerebellum [nTPM]":"12.4","Brain RNA - cerebral cortex [nTPM]":"13.3","Brain RNA - hippocampal formation [nTPM]":"10.4","Brain RNA - hypothalamus [nTPM]":"11.7","Brain RNA - medulla oblongata [nTPM]":"11.7","Brain RNA - midbrain [nTPM]":"13.9","Brain RNA - pons [nTPM]":"13.1","Brain RNA - spinal cord [nTPM]":"11.3","Brain RNA - thalamus [nTPM]":"11.4","Brain RNA - white matter [nTPM]":"12.3","Single Cell Type RNA - Adipocytes [nTPM]":"5.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.4","Single Cell Type RNA - Astrocytes [nTPM]":"27.7","Single Cell Type RNA - B-cells [nTPM]":"14.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Bipolar cells [nTPM]":"5.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"10.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.0","Single Cell Type RNA - dendritic cells [nTPM]":"4.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"29.4","Single Cell Type RNA - Ductal cells [nTPM]":"9.5","Single Cell Type RNA - Early spermatids [nTPM]":"13.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.4","Single Cell Type RNA - Endothelial cells [nTPM]":"6.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.0","Single Cell Type RNA - Erythroid cells [nTPM]":"9.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"34.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"23.6","Single Cell Type RNA - Fibroblasts [nTPM]":"9.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.0","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"14.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"19.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"45.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.3","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"6.3","Single Cell Type RNA - Langerhans cells [nTPM]":"11.6","Single Cell Type RNA - Late spermatids [nTPM]":"5.4","Single Cell Type RNA - Leydig cells [nTPM]":"7.8","Single Cell Type RNA - Macrophages [nTPM]":"6.3","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"45.0","Single Cell Type RNA - monocytes [nTPM]":"2.9","Single Cell Type RNA - Muller glia cells [nTPM]":"6.3","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"42.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"47.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.5","Single Cell Type RNA - Paneth cells [nTPM]":"9.9","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"14.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"28.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.8","Single Cell Type RNA - Spermatocytes [nTPM]":"8.6","Single Cell Type RNA - Spermatogonia [nTPM]":"19.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.3","Single Cell Type RNA - T-cells [nTPM]":"7.8","Single Cell Type RNA - Theca cells [nTPM]":"9.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.6","Single Cell Type RNA - Urothelial cells [nTPM]":"10.7"},{"Gene":"NAT8L","Gene synonym":["FLJ37478","Hcml3","Shati"],"Ensembl":"ENSG00000185818","Gene description":"N-acetyltransferase 8 like","Uniprot":["Q8N9F0"],"Chromosome":"4","Position":"2059327-2069089","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"adipose tissue":"43.5","brain":"99.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"126.7","Excitatory neurons":"46.0","Horizontal cells":"80.8","Inhibitory neurons":"37.6","Muller glia cells":"25.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"endometrial cancer":"6.2","glioma":"17.2","melanoma":"14.6","ovarian cancer":"8.0","thyroid cancer":"7.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"NB-4":"20.8","SCLC-21H":"25.8","SK-MEL-30":"21.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040677"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA040677":"AB_2732486"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.01e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.24e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Tissue RNA - adipose tissue [nTPM]":"43.5","Tissue RNA - adrenal gland [nTPM]":"0.7","Tissue RNA - amygdala [nTPM]":"56.1","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"46.4","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.6","Tissue RNA - cerebellum [nTPM]":"42.9","Tissue RNA - cerebral cortex [nTPM]":"99.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"1.3","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.8","Tissue RNA - hippocampal formation [nTPM]":"45.8","Tissue RNA - hypothalamus [nTPM]":"29.0","Tissue RNA - kidney [nTPM]":"5.3","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"52.3","Tissue RNA - midbrain [nTPM]":"46.4","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"2.3","Tissue RNA - parathyroid gland [nTPM]":"0.9","Tissue RNA - pituitary gland [nTPM]":"1.8","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"57.5","Tissue RNA - prostate [nTPM]":"1.0","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"3.7","Tissue RNA - salivary gland [nTPM]":"2.3","Tissue RNA - seminal vesicle [nTPM]":"1.6","Tissue RNA - skeletal muscle [nTPM]":"5.7","Tissue RNA - skin 1 [nTPM]":"1.0","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"33.0","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"9.0","Tissue RNA - thalamus [nTPM]":"88.8","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"2.5","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"38.9","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"9.2","Cell RNA - AF22 [nTPM]":"4.9","Cell RNA - AN3-CA [nTPM]":"10.0","Cell RNA - ASC diff [nTPM]":"0.9","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"5.7","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"4.1","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.9","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"1.5","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"11.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"13.2","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"2.1","Cell RNA - Hep G2 [nTPM]":"6.6","Cell RNA - HHSteC [nTPM]":"1.5","Cell RNA - HL-60 [nTPM]":"14.5","Cell RNA - HMC-1 [nTPM]":"6.9","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"1.8","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"3.4","Cell RNA - K-562 [nTPM]":"11.5","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"6.2","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"20.8","Cell RNA - NTERA-2 [nTPM]":"14.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"4.1","Cell RNA - REH [nTPM]":"0.7","Cell RNA - RH-30 [nTPM]":"2.3","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"25.8","Cell RNA - SH-SY5Y [nTPM]":"8.6","Cell RNA - SiHa [nTPM]":"6.6","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"21.4","Cell RNA - SuSa [nTPM]":"0.8","Cell RNA - T-47d [nTPM]":"0.7","Cell RNA - THP-1 [nTPM]":"8.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"3.3","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"5.6","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"6.0","Cell RNA - WM-115 [nTPM]":"1.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"56.1","Brain RNA - basal ganglia [nTPM]":"46.4","Brain RNA - cerebellum [nTPM]":"42.9","Brain RNA - cerebral cortex [nTPM]":"99.0","Brain RNA - hippocampal formation [nTPM]":"45.8","Brain RNA - hypothalamus [nTPM]":"29.0","Brain RNA - medulla oblongata [nTPM]":"52.3","Brain RNA - midbrain [nTPM]":"46.4","Brain RNA - pons [nTPM]":"57.5","Brain RNA - spinal cord [nTPM]":"33.0","Brain RNA - thalamus [nTPM]":"88.8","Brain RNA - white matter [nTPM]":"38.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"126.7","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"14.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"5.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"4.6","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"46.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"21.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.8","Single Cell Type RNA - Horizontal cells [nTPM]":"80.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"3.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"25.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"23.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"NAXD","Gene synonym":["CARKD","FLJ10769","LP3298"],"Ensembl":"ENSG00000213995","Gene description":"NAD(P)HX dehydratase","Uniprot":["Q8IW45"],"Chromosome":"13","Position":"110615545-110639996","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Lyase"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"34.8","Distal tubular cells":"39.2","Extravillous trophoblasts":"26.7","Granulosa cells":"27.6","Syncytiotrophoblasts":"30.9","Theca cells":"24.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010551"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"390000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA010551":"AB_1848669"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.15e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.63e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Tissue RNA - adipose tissue [nTPM]":"17.3","Tissue RNA - adrenal gland [nTPM]":"37.1","Tissue RNA - amygdala [nTPM]":"44.0","Tissue RNA - appendix [nTPM]":"16.0","Tissue RNA - basal ganglia [nTPM]":"43.7","Tissue RNA - bone marrow [nTPM]":"8.2","Tissue RNA - breast [nTPM]":"19.4","Tissue RNA - cerebellum [nTPM]":"43.6","Tissue RNA - cerebral cortex [nTPM]":"46.3","Tissue RNA - cervix [nTPM]":"16.7","Tissue RNA - choroid plexus [nTPM]":"40.8","Tissue RNA - colon [nTPM]":"23.1","Tissue RNA - duodenum [nTPM]":"22.9","Tissue RNA - endometrium 1 [nTPM]":"18.7","Tissue RNA - epididymis [nTPM]":"26.6","Tissue RNA - esophagus [nTPM]":"23.4","Tissue RNA - fallopian tube [nTPM]":"22.6","Tissue RNA - gallbladder [nTPM]":"21.3","Tissue RNA - heart muscle [nTPM]":"26.4","Tissue RNA - hippocampal formation [nTPM]":"45.7","Tissue RNA - hypothalamus [nTPM]":"42.8","Tissue RNA - kidney [nTPM]":"24.9","Tissue RNA - liver [nTPM]":"65.4","Tissue RNA - lung [nTPM]":"18.8","Tissue RNA - lymph node [nTPM]":"20.8","Tissue RNA - medulla oblongata [nTPM]":"45.9","Tissue RNA - midbrain [nTPM]":"45.0","Tissue RNA - ovary [nTPM]":"39.0","Tissue RNA - pancreas [nTPM]":"36.2","Tissue RNA - parathyroid gland [nTPM]":"28.4","Tissue RNA - pituitary gland [nTPM]":"22.4","Tissue RNA - placenta [nTPM]":"23.3","Tissue RNA - pons [nTPM]":"44.5","Tissue RNA - prostate [nTPM]":"25.8","Tissue RNA - rectum [nTPM]":"19.7","Tissue RNA - retina [nTPM]":"14.3","Tissue RNA - salivary gland [nTPM]":"22.8","Tissue RNA - seminal vesicle [nTPM]":"28.9","Tissue RNA - skeletal muscle [nTPM]":"31.9","Tissue RNA - skin 1 [nTPM]":"30.5","Tissue RNA - small intestine [nTPM]":"23.0","Tissue RNA - smooth muscle [nTPM]":"21.7","Tissue RNA - spinal cord [nTPM]":"43.9","Tissue RNA - spleen [nTPM]":"21.8","Tissue RNA - stomach 1 [nTPM]":"30.3","Tissue RNA - testis [nTPM]":"24.2","Tissue RNA - thalamus [nTPM]":"46.2","Tissue RNA - thymus [nTPM]":"18.3","Tissue RNA - thyroid gland [nTPM]":"25.4","Tissue RNA - tongue [nTPM]":"33.6","Tissue RNA - tonsil [nTPM]":"17.1","Tissue RNA - urinary bladder [nTPM]":"17.3","Tissue RNA - vagina [nTPM]":"15.0","Tissue RNA - white matter [nTPM]":"45.2","Cell RNA - A-431 [nTPM]":"36.0","Cell RNA - A549 [nTPM]":"15.7","Cell RNA - AF22 [nTPM]":"28.1","Cell RNA - AN3-CA [nTPM]":"24.3","Cell RNA - ASC diff [nTPM]":"29.8","Cell RNA - ASC TERT1 [nTPM]":"23.6","Cell RNA - BEWO [nTPM]":"35.4","Cell RNA - BJ [nTPM]":"27.9","Cell RNA - BJ hTERT+ [nTPM]":"22.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"26.2","Cell RNA - CACO-2 [nTPM]":"43.9","Cell RNA - CAPAN-2 [nTPM]":"35.1","Cell RNA - Daudi [nTPM]":"7.3","Cell RNA - EFO-21 [nTPM]":"28.4","Cell RNA - fHDF\/TERT166 [nTPM]":"21.7","Cell RNA - GAMG [nTPM]":"25.3","Cell RNA - HaCaT [nTPM]":"28.1","Cell RNA - HAP1 [nTPM]":"16.3","Cell RNA - HBEC3-KT [nTPM]":"24.4","Cell RNA - HBF TERT88 [nTPM]":"16.0","Cell RNA - HDLM-2 [nTPM]":"31.6","Cell RNA - HEK 293 [nTPM]":"27.4","Cell RNA - HEL [nTPM]":"22.5","Cell RNA - HeLa [nTPM]":"47.9","Cell RNA - Hep G2 [nTPM]":"23.5","Cell RNA - HHSteC [nTPM]":"34.2","Cell RNA - HL-60 [nTPM]":"29.3","Cell RNA - HMC-1 [nTPM]":"20.2","Cell RNA - HSkMC [nTPM]":"29.1","Cell RNA - hTCEpi [nTPM]":"42.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.8","Cell RNA - hTERT-HME1 [nTPM]":"17.7","Cell RNA - hTERT-RPE1 [nTPM]":"32.5","Cell RNA - HUVEC TERT2 [nTPM]":"21.9","Cell RNA - JURKAT [nTPM]":"31.8","Cell RNA - K-562 [nTPM]":"19.6","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"22.3","Cell RNA - MCF7 [nTPM]":"30.0","Cell RNA - MOLT-4 [nTPM]":"23.1","Cell RNA - NB-4 [nTPM]":"48.4","Cell RNA - NTERA-2 [nTPM]":"21.2","Cell RNA - OE19 [nTPM]":"64.4","Cell RNA - PC-3 [nTPM]":"17.2","Cell RNA - REH [nTPM]":"8.2","Cell RNA - RH-30 [nTPM]":"14.4","Cell RNA - RPMI-8226 [nTPM]":"5.9","Cell RNA - RPTEC TERT1 [nTPM]":"30.3","Cell RNA - RT4 [nTPM]":"30.1","Cell RNA - SCLC-21H [nTPM]":"42.5","Cell RNA - SH-SY5Y [nTPM]":"28.6","Cell RNA - SiHa [nTPM]":"16.8","Cell RNA - SK-BR-3 [nTPM]":"75.4","Cell RNA - SK-MEL-30 [nTPM]":"21.6","Cell RNA - SuSa [nTPM]":"18.5","Cell RNA - T-47d [nTPM]":"39.7","Cell RNA - THP-1 [nTPM]":"54.4","Cell RNA - TIME [nTPM]":"25.3","Cell RNA - U-138 MG [nTPM]":"17.1","Cell RNA - U-2 OS [nTPM]":"14.3","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"22.4","Cell RNA - U-266\/70 [nTPM]":"25.6","Cell RNA - U-266\/84 [nTPM]":"18.7","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"27.7","Cell RNA - U-937 [nTPM]":"8.7","Cell RNA - WM-115 [nTPM]":"28.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"8.3","Blood RNA - eosinophil [nTPM]":"0.8","Blood RNA - gdT-cell [nTPM]":"9.6","Blood RNA - intermediate monocyte [nTPM]":"9.0","Blood RNA - MAIT T-cell [nTPM]":"6.3","Blood RNA - memory B-cell [nTPM]":"8.4","Blood RNA - memory CD4 T-cell [nTPM]":"9.6","Blood RNA - memory CD8 T-cell [nTPM]":"8.9","Blood RNA - myeloid DC [nTPM]":"10.4","Blood RNA - naive B-cell [nTPM]":"8.2","Blood RNA - naive CD4 T-cell [nTPM]":"9.9","Blood RNA - naive CD8 T-cell [nTPM]":"9.1","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"9.2","Blood RNA - non-classical monocyte [nTPM]":"6.5","Blood RNA - plasmacytoid DC [nTPM]":"10.1","Blood RNA - T-reg [nTPM]":"10.5","Blood RNA - total PBMC [nTPM]":"8.3","Brain RNA - amygdala [nTPM]":"44.0","Brain RNA - basal ganglia [nTPM]":"43.7","Brain RNA - cerebellum [nTPM]":"43.6","Brain RNA - cerebral cortex [nTPM]":"46.3","Brain RNA - hippocampal formation [nTPM]":"45.7","Brain RNA - hypothalamus [nTPM]":"42.8","Brain RNA - medulla oblongata [nTPM]":"45.9","Brain RNA - midbrain [nTPM]":"45.0","Brain RNA - pons [nTPM]":"44.5","Brain RNA - spinal cord [nTPM]":"43.9","Brain RNA - thalamus [nTPM]":"46.2","Brain RNA - white matter [nTPM]":"45.2","Single Cell Type RNA - Adipocytes [nTPM]":"9.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"9.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"34.8","Single Cell Type RNA - dendritic cells [nTPM]":"5.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"39.2","Single Cell Type RNA - Ductal cells [nTPM]":"15.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.5","Single Cell Type RNA - Endothelial cells [nTPM]":"4.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.7","Single Cell Type RNA - Fibroblasts [nTPM]":"6.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.8","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"27.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"3.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"10.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"30.9","Single Cell Type RNA - T-cells [nTPM]":"2.1","Single Cell Type RNA - Theca cells [nTPM]":"24.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"NAXE","Gene synonym":["AIBP","APOA1BP","MGC119143","MGC119144","MGC119145","YJEFN1"],"Ensembl":"ENSG00000163382","Gene description":"NAD(P)HX epimerase","Uniprot":["Q8NCW5"],"Chromosome":"1","Position":"156591756-156609507","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted secreted proteins"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Isomerase"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"136.7","Distal tubular cells":"201.5","Ductal cells":"112.8","Exocrine glandular cells":"100.1","Proximal tubular cells":"219.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043766","HPA048164"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3300000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"HPA043766":"AB_2678660","HPA048164":"AB_2680294"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.94e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-1"},"Tissue RNA - adipose tissue [nTPM]":"47.1","Tissue RNA - adrenal gland [nTPM]":"74.8","Tissue RNA - amygdala [nTPM]":"61.0","Tissue RNA - appendix [nTPM]":"20.9","Tissue RNA - basal ganglia [nTPM]":"63.7","Tissue RNA - bone marrow [nTPM]":"22.2","Tissue RNA - breast [nTPM]":"47.9","Tissue RNA - cerebellum [nTPM]":"66.1","Tissue RNA - cerebral cortex [nTPM]":"69.6","Tissue RNA - cervix [nTPM]":"56.8","Tissue RNA - choroid plexus [nTPM]":"71.1","Tissue RNA - colon [nTPM]":"62.9","Tissue RNA - duodenum [nTPM]":"45.5","Tissue RNA - endometrium 1 [nTPM]":"68.8","Tissue RNA - epididymis [nTPM]":"88.7","Tissue RNA - esophagus [nTPM]":"58.0","Tissue RNA - fallopian tube [nTPM]":"59.5","Tissue RNA - gallbladder [nTPM]":"26.5","Tissue RNA - heart muscle [nTPM]":"111.1","Tissue RNA - hippocampal formation [nTPM]":"60.9","Tissue RNA - hypothalamus [nTPM]":"64.3","Tissue RNA - kidney [nTPM]":"83.8","Tissue RNA - liver [nTPM]":"86.5","Tissue RNA - lung [nTPM]":"43.6","Tissue RNA - lymph node [nTPM]":"27.0","Tissue RNA - medulla oblongata [nTPM]":"62.7","Tissue RNA - midbrain [nTPM]":"64.8","Tissue RNA - ovary [nTPM]":"46.5","Tissue RNA - pancreas [nTPM]":"69.7","Tissue RNA - parathyroid gland [nTPM]":"104.7","Tissue RNA - pituitary gland [nTPM]":"70.0","Tissue RNA - placenta [nTPM]":"23.7","Tissue RNA - pons [nTPM]":"61.8","Tissue RNA - prostate [nTPM]":"62.5","Tissue RNA - rectum [nTPM]":"41.6","Tissue RNA - retina [nTPM]":"17.4","Tissue RNA - salivary gland [nTPM]":"53.9","Tissue RNA - seminal vesicle [nTPM]":"48.3","Tissue RNA - skeletal muscle [nTPM]":"71.8","Tissue RNA - skin 1 [nTPM]":"55.8","Tissue RNA - small intestine [nTPM]":"48.3","Tissue RNA - smooth muscle [nTPM]":"39.7","Tissue RNA - spinal cord [nTPM]":"64.7","Tissue RNA - spleen [nTPM]":"43.2","Tissue RNA - stomach 1 [nTPM]":"67.5","Tissue RNA - testis [nTPM]":"40.8","Tissue RNA - thalamus [nTPM]":"63.5","Tissue RNA - thymus [nTPM]":"30.6","Tissue RNA - thyroid gland [nTPM]":"59.8","Tissue RNA - tongue [nTPM]":"68.2","Tissue RNA - tonsil [nTPM]":"34.3","Tissue RNA - urinary bladder [nTPM]":"55.0","Tissue RNA - vagina [nTPM]":"47.8","Tissue RNA - white matter [nTPM]":"70.5","Cell RNA - A-431 [nTPM]":"114.2","Cell RNA - A549 [nTPM]":"155.4","Cell RNA - AF22 [nTPM]":"43.9","Cell RNA - AN3-CA [nTPM]":"84.4","Cell RNA - ASC diff [nTPM]":"64.0","Cell RNA - ASC TERT1 [nTPM]":"43.8","Cell RNA - BEWO [nTPM]":"55.5","Cell RNA - BJ [nTPM]":"29.5","Cell RNA - BJ hTERT+ [nTPM]":"62.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"69.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"72.6","Cell RNA - CACO-2 [nTPM]":"130.6","Cell RNA - CAPAN-2 [nTPM]":"76.8","Cell RNA - Daudi [nTPM]":"62.4","Cell RNA - EFO-21 [nTPM]":"113.4","Cell RNA - fHDF\/TERT166 [nTPM]":"52.5","Cell RNA - GAMG [nTPM]":"55.9","Cell RNA - HaCaT [nTPM]":"111.1","Cell RNA - HAP1 [nTPM]":"49.4","Cell RNA - HBEC3-KT [nTPM]":"99.0","Cell RNA - HBF TERT88 [nTPM]":"47.5","Cell RNA - HDLM-2 [nTPM]":"81.2","Cell RNA - HEK 293 [nTPM]":"98.5","Cell RNA - HEL [nTPM]":"58.1","Cell RNA - HeLa [nTPM]":"76.2","Cell RNA - Hep G2 [nTPM]":"86.1","Cell RNA - HHSteC [nTPM]":"75.1","Cell RNA - HL-60 [nTPM]":"60.0","Cell RNA - HMC-1 [nTPM]":"60.9","Cell RNA - HSkMC [nTPM]":"44.2","Cell RNA - hTCEpi [nTPM]":"123.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"87.9","Cell RNA - hTERT-HME1 [nTPM]":"81.9","Cell RNA - hTERT-RPE1 [nTPM]":"53.4","Cell RNA - HUVEC TERT2 [nTPM]":"95.4","Cell RNA - JURKAT [nTPM]":"104.7","Cell RNA - K-562 [nTPM]":"54.7","Cell RNA - Karpas-707 [nTPM]":"70.1","Cell RNA - LHCN-M2 [nTPM]":"71.6","Cell RNA - MCF7 [nTPM]":"209.6","Cell RNA - MOLT-4 [nTPM]":"83.3","Cell RNA - NB-4 [nTPM]":"98.0","Cell RNA - NTERA-2 [nTPM]":"43.1","Cell RNA - OE19 [nTPM]":"158.1","Cell RNA - PC-3 [nTPM]":"118.2","Cell RNA - REH [nTPM]":"87.7","Cell RNA - RH-30 [nTPM]":"40.2","Cell RNA - RPMI-8226 [nTPM]":"212.6","Cell RNA - RPTEC TERT1 [nTPM]":"93.0","Cell RNA - RT4 [nTPM]":"93.6","Cell RNA - SCLC-21H [nTPM]":"114.7","Cell RNA - SH-SY5Y [nTPM]":"102.9","Cell RNA - SiHa [nTPM]":"90.4","Cell RNA - SK-BR-3 [nTPM]":"172.4","Cell RNA - SK-MEL-30 [nTPM]":"141.6","Cell RNA - SuSa [nTPM]":"66.4","Cell RNA - T-47d [nTPM]":"178.3","Cell RNA - THP-1 [nTPM]":"117.5","Cell RNA - TIME [nTPM]":"51.1","Cell RNA - U-138 MG [nTPM]":"45.1","Cell RNA - U-2 OS [nTPM]":"64.8","Cell RNA - U-2197 [nTPM]":"64.6","Cell RNA - U-251 MG [nTPM]":"70.6","Cell RNA - U-266\/70 [nTPM]":"180.1","Cell RNA - U-266\/84 [nTPM]":"110.3","Cell RNA - U-698 [nTPM]":"53.0","Cell RNA - U-87 MG [nTPM]":"63.1","Cell RNA - U-937 [nTPM]":"37.0","Cell RNA - WM-115 [nTPM]":"70.4","Blood RNA - basophil [nTPM]":"25.4","Blood RNA - classical monocyte [nTPM]":"96.3","Blood RNA - eosinophil [nTPM]":"52.9","Blood RNA - gdT-cell [nTPM]":"121.2","Blood RNA - intermediate monocyte [nTPM]":"111.3","Blood RNA - MAIT T-cell [nTPM]":"121.3","Blood RNA - memory B-cell [nTPM]":"236.2","Blood RNA - memory CD4 T-cell [nTPM]":"109.4","Blood RNA - memory CD8 T-cell [nTPM]":"124.3","Blood RNA - myeloid DC [nTPM]":"89.1","Blood RNA - naive B-cell [nTPM]":"186.5","Blood RNA - naive CD4 T-cell [nTPM]":"122.8","Blood RNA - naive CD8 T-cell [nTPM]":"114.9","Blood RNA - neutrophil [nTPM]":"11.4","Blood RNA - NK-cell [nTPM]":"141.3","Blood RNA - non-classical monocyte [nTPM]":"89.1","Blood RNA - plasmacytoid DC [nTPM]":"225.7","Blood RNA - T-reg [nTPM]":"110.1","Blood RNA - total PBMC [nTPM]":"186.6","Brain RNA - amygdala [nTPM]":"61.0","Brain RNA - basal ganglia [nTPM]":"63.7","Brain RNA - cerebellum [nTPM]":"66.1","Brain RNA - cerebral cortex [nTPM]":"69.6","Brain RNA - hippocampal formation [nTPM]":"60.9","Brain RNA - hypothalamus [nTPM]":"64.3","Brain RNA - medulla oblongata [nTPM]":"62.7","Brain RNA - midbrain [nTPM]":"64.8","Brain RNA - pons [nTPM]":"61.8","Brain RNA - spinal cord [nTPM]":"64.7","Brain RNA - thalamus [nTPM]":"63.5","Brain RNA - white matter [nTPM]":"70.5","Single Cell Type RNA - Adipocytes [nTPM]":"29.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"32.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"14.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"87.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"96.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"23.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"68.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"136.7","Single Cell Type RNA - dendritic cells [nTPM]":"28.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"201.5","Single Cell Type RNA - Ductal cells [nTPM]":"112.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.9","Single Cell Type RNA - Endothelial cells [nTPM]":"18.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"100.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"43.1","Single Cell Type RNA - Fibroblasts [nTPM]":"27.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"32.0","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"53.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"92.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"19.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"40.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"91.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"6.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"219.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"24.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"81.3","Single Cell Type RNA - T-cells [nTPM]":"13.4","Single Cell Type RNA - Theca cells [nTPM]":"48.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"NCOA1","Gene synonym":["bHLHe74","F-SRC-1","KAT13A","NCoA-1","RIP160","SRC1"],"Ensembl":"ENSG00000084676","Gene description":"Nuclear receptor coactivator 1","Uniprot":["Q15788"],"Chromosome":"2","Position":"24491914-24770702","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","Acyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"467.5","Excitatory neurons":"313.0","Inhibitory neurons":"421.8","Microglial cells":"341.9","Oligodendrocyte precursor cells":"459.4","Oligodendrocytes":"305.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RH-30":"81.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB019402","HPA070213","HPA070520"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Plasma membrane","Cytosol"],"Antibody RRID":{"CAB019402":"AB_2196189","HPA070213":"AB_2686235","HPA070520":"AB_2686276"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Tissue RNA - adipose tissue [nTPM]":"16.6","Tissue RNA - adrenal gland [nTPM]":"15.1","Tissue RNA - amygdala [nTPM]":"24.0","Tissue RNA - appendix [nTPM]":"13.3","Tissue RNA - basal ganglia [nTPM]":"25.4","Tissue RNA - bone marrow [nTPM]":"17.3","Tissue RNA - breast [nTPM]":"17.3","Tissue RNA - cerebellum [nTPM]":"24.6","Tissue RNA - cerebral cortex [nTPM]":"28.2","Tissue RNA - cervix [nTPM]":"18.6","Tissue RNA - choroid plexus [nTPM]":"13.6","Tissue RNA - colon [nTPM]":"15.9","Tissue RNA - duodenum [nTPM]":"20.9","Tissue RNA - endometrium 1 [nTPM]":"19.0","Tissue RNA - epididymis [nTPM]":"12.8","Tissue RNA - esophagus [nTPM]":"17.6","Tissue RNA - fallopian tube [nTPM]":"15.7","Tissue RNA - gallbladder [nTPM]":"14.0","Tissue RNA - heart muscle [nTPM]":"15.3","Tissue RNA - hippocampal formation [nTPM]":"29.6","Tissue RNA - hypothalamus [nTPM]":"19.5","Tissue RNA - kidney [nTPM]":"18.9","Tissue RNA - liver [nTPM]":"15.0","Tissue RNA - lung [nTPM]":"16.0","Tissue RNA - lymph node [nTPM]":"15.3","Tissue RNA - medulla oblongata [nTPM]":"17.7","Tissue RNA - midbrain [nTPM]":"19.2","Tissue RNA - ovary [nTPM]":"26.6","Tissue RNA - pancreas [nTPM]":"17.4","Tissue RNA - parathyroid gland [nTPM]":"30.0","Tissue RNA - pituitary gland [nTPM]":"16.6","Tissue RNA - placenta [nTPM]":"17.1","Tissue RNA - pons [nTPM]":"16.0","Tissue RNA - prostate [nTPM]":"15.2","Tissue RNA - rectum [nTPM]":"16.6","Tissue RNA - retina [nTPM]":"47.3","Tissue RNA - salivary gland [nTPM]":"16.0","Tissue RNA - seminal vesicle [nTPM]":"20.2","Tissue RNA - skeletal muscle [nTPM]":"33.4","Tissue RNA - skin 1 [nTPM]":"15.7","Tissue RNA - small intestine [nTPM]":"18.9","Tissue RNA - smooth muscle [nTPM]":"19.0","Tissue RNA - spinal cord [nTPM]":"19.5","Tissue RNA - spleen [nTPM]":"16.3","Tissue RNA - stomach 1 [nTPM]":"12.5","Tissue RNA - testis [nTPM]":"19.9","Tissue RNA - thalamus [nTPM]":"21.8","Tissue RNA - thymus [nTPM]":"26.1","Tissue RNA - thyroid gland [nTPM]":"11.8","Tissue RNA - tongue [nTPM]":"36.1","Tissue RNA - tonsil [nTPM]":"16.3","Tissue RNA - urinary bladder [nTPM]":"14.9","Tissue RNA - vagina [nTPM]":"15.5","Tissue RNA - white matter [nTPM]":"22.3","Cell RNA - A-431 [nTPM]":"14.1","Cell RNA - A549 [nTPM]":"10.3","Cell RNA - AF22 [nTPM]":"17.7","Cell RNA - AN3-CA [nTPM]":"9.2","Cell RNA - ASC diff [nTPM]":"19.2","Cell RNA - ASC TERT1 [nTPM]":"17.3","Cell RNA - BEWO [nTPM]":"26.9","Cell RNA - BJ [nTPM]":"7.4","Cell RNA - BJ hTERT+ [nTPM]":"14.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.1","Cell RNA - CACO-2 [nTPM]":"9.6","Cell RNA - CAPAN-2 [nTPM]":"5.9","Cell RNA - Daudi [nTPM]":"10.2","Cell RNA - EFO-21 [nTPM]":"3.1","Cell RNA - fHDF\/TERT166 [nTPM]":"13.5","Cell RNA - GAMG [nTPM]":"17.4","Cell RNA - HaCaT [nTPM]":"3.4","Cell RNA - HAP1 [nTPM]":"10.7","Cell RNA - HBEC3-KT [nTPM]":"6.3","Cell RNA - HBF TERT88 [nTPM]":"9.8","Cell RNA - HDLM-2 [nTPM]":"48.6","Cell RNA - HEK 293 [nTPM]":"15.5","Cell RNA - HEL [nTPM]":"36.5","Cell RNA - HeLa [nTPM]":"4.1","Cell RNA - Hep G2 [nTPM]":"4.1","Cell RNA - HHSteC [nTPM]":"12.0","Cell RNA - HL-60 [nTPM]":"16.9","Cell RNA - HMC-1 [nTPM]":"29.1","Cell RNA - HSkMC [nTPM]":"27.9","Cell RNA - hTCEpi [nTPM]":"9.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.8","Cell RNA - hTERT-HME1 [nTPM]":"7.1","Cell RNA - hTERT-RPE1 [nTPM]":"11.3","Cell RNA - HUVEC TERT2 [nTPM]":"9.4","Cell RNA - JURKAT [nTPM]":"12.9","Cell RNA - K-562 [nTPM]":"22.6","Cell RNA - Karpas-707 [nTPM]":"16.5","Cell RNA - LHCN-M2 [nTPM]":"14.0","Cell RNA - MCF7 [nTPM]":"9.4","Cell RNA - MOLT-4 [nTPM]":"15.1","Cell RNA - NB-4 [nTPM]":"6.0","Cell RNA - NTERA-2 [nTPM]":"8.5","Cell RNA - OE19 [nTPM]":"8.2","Cell RNA - PC-3 [nTPM]":"6.8","Cell RNA - REH [nTPM]":"11.8","Cell RNA - RH-30 [nTPM]":"81.5","Cell RNA - RPMI-8226 [nTPM]":"5.1","Cell RNA - RPTEC TERT1 [nTPM]":"9.9","Cell RNA - RT4 [nTPM]":"18.9","Cell RNA - SCLC-21H [nTPM]":"16.2","Cell RNA - SH-SY5Y [nTPM]":"12.8","Cell RNA - SiHa [nTPM]":"17.1","Cell RNA - SK-BR-3 [nTPM]":"10.2","Cell RNA - SK-MEL-30 [nTPM]":"7.4","Cell RNA - SuSa [nTPM]":"9.3","Cell RNA - T-47d [nTPM]":"12.3","Cell RNA - THP-1 [nTPM]":"8.6","Cell RNA - TIME [nTPM]":"10.2","Cell RNA - U-138 MG [nTPM]":"15.2","Cell RNA - U-2 OS [nTPM]":"11.9","Cell RNA - U-2197 [nTPM]":"10.5","Cell RNA - U-251 MG [nTPM]":"7.5","Cell RNA - U-266\/70 [nTPM]":"18.8","Cell RNA - U-266\/84 [nTPM]":"17.5","Cell RNA - U-698 [nTPM]":"17.2","Cell RNA - U-87 MG [nTPM]":"8.6","Cell RNA - U-937 [nTPM]":"10.5","Cell RNA - WM-115 [nTPM]":"7.7","Blood RNA - basophil [nTPM]":"10.6","Blood RNA - classical monocyte [nTPM]":"3.3","Blood RNA - eosinophil [nTPM]":"7.0","Blood RNA - gdT-cell [nTPM]":"3.4","Blood RNA - intermediate monocyte [nTPM]":"2.6","Blood RNA - MAIT T-cell [nTPM]":"3.8","Blood RNA - memory B-cell [nTPM]":"1.6","Blood RNA - memory CD4 T-cell [nTPM]":"3.0","Blood RNA - memory CD8 T-cell [nTPM]":"3.8","Blood RNA - myeloid DC [nTPM]":"2.5","Blood RNA - naive B-cell [nTPM]":"2.4","Blood RNA - naive CD4 T-cell [nTPM]":"2.9","Blood RNA - naive CD8 T-cell [nTPM]":"3.5","Blood RNA - neutrophil [nTPM]":"13.8","Blood RNA - NK-cell [nTPM]":"3.5","Blood RNA - non-classical monocyte [nTPM]":"2.9","Blood RNA - plasmacytoid DC [nTPM]":"5.2","Blood RNA - T-reg [nTPM]":"3.7","Blood RNA - total PBMC [nTPM]":"2.0","Brain RNA - amygdala [nTPM]":"24.0","Brain RNA - basal ganglia [nTPM]":"25.4","Brain RNA - cerebellum [nTPM]":"24.6","Brain RNA - cerebral cortex [nTPM]":"28.2","Brain RNA - hippocampal formation [nTPM]":"29.6","Brain RNA - hypothalamus [nTPM]":"19.5","Brain RNA - medulla oblongata [nTPM]":"17.7","Brain RNA - midbrain [nTPM]":"19.2","Brain RNA - pons [nTPM]":"16.0","Brain RNA - spinal cord [nTPM]":"19.5","Brain RNA - thalamus [nTPM]":"21.8","Brain RNA - white matter [nTPM]":"22.3","Single Cell Type RNA - Adipocytes [nTPM]":"41.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.5","Single Cell Type RNA - Astrocytes [nTPM]":"467.5","Single Cell Type RNA - B-cells [nTPM]":"16.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"96.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"32.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"26.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"41.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"22.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.1","Single Cell Type RNA - dendritic cells [nTPM]":"47.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"39.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"16.5","Single Cell Type RNA - Early spermatids [nTPM]":"29.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"37.6","Single Cell Type RNA - Endothelial cells [nTPM]":"34.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"25.2","Single Cell Type RNA - Erythroid cells [nTPM]":"29.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"313.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.1","Single Cell Type RNA - Fibroblasts [nTPM]":"39.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"28.4","Single Cell Type RNA - granulocytes [nTPM]":"20.2","Single Cell Type RNA - Granulosa cells [nTPM]":"52.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"36.8","Single Cell Type RNA - Hepatocytes [nTPM]":"22.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.9","Single Cell Type RNA - Horizontal cells [nTPM]":"62.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"421.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.7","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"29.8","Single Cell Type RNA - Langerhans cells [nTPM]":"30.3","Single Cell Type RNA - Late spermatids [nTPM]":"7.4","Single Cell Type RNA - Leydig cells [nTPM]":"47.2","Single Cell Type RNA - Macrophages [nTPM]":"37.7","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"341.9","Single Cell Type RNA - monocytes [nTPM]":"34.7","Single Cell Type RNA - Muller glia cells [nTPM]":"66.7","Single Cell Type RNA - NK-cells [nTPM]":"78.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"459.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"305.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.1","Single Cell Type RNA - Paneth cells [nTPM]":"33.5","Single Cell Type RNA - Peritubular cells [nTPM]":"43.2","Single Cell Type RNA - Plasma cells [nTPM]":"14.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"30.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"71.6","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"116.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"34.4","Single Cell Type RNA - Spermatocytes [nTPM]":"37.7","Single Cell Type RNA - Spermatogonia [nTPM]":"37.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"31.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.3","Single Cell Type RNA - T-cells [nTPM]":"33.4","Single Cell Type RNA - Theca cells [nTPM]":"27.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.1","Single Cell Type RNA - Urothelial cells [nTPM]":"21.7"},{"Gene":"NDST1","Gene synonym":["HSST","NST1"],"Ensembl":"ENSG00000070614","Gene description":"N-deacetylase and N-sulfotransferase 1","Uniprot":["P52848"],"Chromosome":"5","Position":"150485818-150558211","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Inflammatory response"],"Molecular function":["Hydrolase","Multifunctional enzyme","Transferase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"47.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"basophil":"1.4","classical monocyte":"5.5","eosinophil":"3.6","intermediate monocyte":"1.7","myeloid DC":"4.2","neutrophil":"5.4","non-classical monocyte":"4.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"dendritic cells":"4.2","granulocytes":"5.4","monocytes":"5.5"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060532"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1400000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA060532":"AB_2684310"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.99e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.13e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-2"},"Tissue RNA - adipose tissue [nTPM]":"37.2","Tissue RNA - adrenal gland [nTPM]":"22.7","Tissue RNA - amygdala [nTPM]":"39.4","Tissue RNA - appendix [nTPM]":"14.0","Tissue RNA - basal ganglia [nTPM]":"45.1","Tissue RNA - bone marrow [nTPM]":"7.6","Tissue RNA - breast [nTPM]":"28.6","Tissue RNA - cerebellum [nTPM]":"43.8","Tissue RNA - cerebral cortex [nTPM]":"38.9","Tissue RNA - cervix [nTPM]":"16.0","Tissue RNA - choroid plexus [nTPM]":"3.9","Tissue RNA - colon [nTPM]":"17.6","Tissue RNA - duodenum [nTPM]":"12.5","Tissue RNA - endometrium 1 [nTPM]":"17.3","Tissue RNA - epididymis [nTPM]":"7.9","Tissue RNA - esophagus [nTPM]":"38.8","Tissue RNA - fallopian tube [nTPM]":"14.7","Tissue RNA - gallbladder [nTPM]":"15.2","Tissue RNA - heart muscle [nTPM]":"26.8","Tissue RNA - hippocampal formation [nTPM]":"30.8","Tissue RNA - hypothalamus [nTPM]":"30.7","Tissue RNA - kidney [nTPM]":"15.4","Tissue RNA - liver [nTPM]":"42.6","Tissue RNA - lung [nTPM]":"34.3","Tissue RNA - lymph node [nTPM]":"7.3","Tissue RNA - medulla oblongata [nTPM]":"62.6","Tissue RNA - midbrain [nTPM]":"48.8","Tissue RNA - ovary [nTPM]":"23.0","Tissue RNA - pancreas [nTPM]":"39.7","Tissue RNA - parathyroid gland [nTPM]":"20.5","Tissue RNA - pituitary gland [nTPM]":"6.7","Tissue RNA - placenta [nTPM]":"12.2","Tissue RNA - pons [nTPM]":"50.3","Tissue RNA - prostate [nTPM]":"14.5","Tissue RNA - rectum [nTPM]":"9.5","Tissue RNA - retina [nTPM]":"13.9","Tissue RNA - salivary gland [nTPM]":"37.4","Tissue RNA - seminal vesicle [nTPM]":"16.8","Tissue RNA - skeletal muscle [nTPM]":"23.6","Tissue RNA - skin 1 [nTPM]":"34.2","Tissue RNA - small intestine [nTPM]":"17.4","Tissue RNA - smooth muscle [nTPM]":"19.2","Tissue RNA - spinal cord [nTPM]":"47.8","Tissue RNA - spleen [nTPM]":"43.4","Tissue RNA - stomach 1 [nTPM]":"16.0","Tissue RNA - testis [nTPM]":"14.5","Tissue RNA - thalamus [nTPM]":"51.5","Tissue RNA - thymus [nTPM]":"4.2","Tissue RNA - thyroid gland [nTPM]":"22.9","Tissue RNA - tongue [nTPM]":"13.0","Tissue RNA - tonsil [nTPM]":"9.9","Tissue RNA - urinary bladder [nTPM]":"14.1","Tissue RNA - vagina [nTPM]":"18.7","Tissue RNA - white matter [nTPM]":"60.0","Cell RNA - A-431 [nTPM]":"32.4","Cell RNA - A549 [nTPM]":"28.3","Cell RNA - AF22 [nTPM]":"46.1","Cell RNA - AN3-CA [nTPM]":"56.4","Cell RNA - ASC diff [nTPM]":"45.3","Cell RNA - ASC TERT1 [nTPM]":"44.9","Cell RNA - BEWO [nTPM]":"46.3","Cell RNA - BJ [nTPM]":"58.1","Cell RNA - BJ hTERT+ [nTPM]":"75.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"56.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"84.8","Cell RNA - CACO-2 [nTPM]":"84.1","Cell RNA - CAPAN-2 [nTPM]":"33.3","Cell RNA - Daudi [nTPM]":"22.0","Cell RNA - EFO-21 [nTPM]":"57.6","Cell RNA - fHDF\/TERT166 [nTPM]":"116.8","Cell RNA - GAMG [nTPM]":"91.0","Cell RNA - HaCaT [nTPM]":"54.4","Cell RNA - HAP1 [nTPM]":"25.1","Cell RNA - HBEC3-KT [nTPM]":"118.0","Cell RNA - HBF TERT88 [nTPM]":"37.6","Cell RNA - HDLM-2 [nTPM]":"2.6","Cell RNA - HEK 293 [nTPM]":"38.9","Cell RNA - HEL [nTPM]":"26.0","Cell RNA - HeLa [nTPM]":"18.5","Cell RNA - Hep G2 [nTPM]":"13.2","Cell RNA - HHSteC [nTPM]":"33.5","Cell RNA - HL-60 [nTPM]":"19.5","Cell RNA - HMC-1 [nTPM]":"45.5","Cell RNA - HSkMC [nTPM]":"61.6","Cell RNA - hTCEpi [nTPM]":"48.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"68.7","Cell RNA - hTERT-HME1 [nTPM]":"31.0","Cell RNA - hTERT-RPE1 [nTPM]":"56.9","Cell RNA - HUVEC TERT2 [nTPM]":"78.3","Cell RNA - JURKAT [nTPM]":"12.9","Cell RNA - K-562 [nTPM]":"25.3","Cell RNA - Karpas-707 [nTPM]":"7.8","Cell RNA - LHCN-M2 [nTPM]":"56.3","Cell RNA - MCF7 [nTPM]":"27.5","Cell RNA - MOLT-4 [nTPM]":"2.3","Cell RNA - NB-4 [nTPM]":"6.2","Cell RNA - NTERA-2 [nTPM]":"21.6","Cell RNA - OE19 [nTPM]":"9.1","Cell RNA - PC-3 [nTPM]":"33.0","Cell RNA - REH [nTPM]":"37.6","Cell RNA - RH-30 [nTPM]":"38.4","Cell RNA - RPMI-8226 [nTPM]":"9.8","Cell RNA - RPTEC TERT1 [nTPM]":"33.4","Cell RNA - RT4 [nTPM]":"32.5","Cell RNA - SCLC-21H [nTPM]":"13.8","Cell RNA - SH-SY5Y [nTPM]":"48.3","Cell RNA - SiHa [nTPM]":"35.2","Cell RNA - SK-BR-3 [nTPM]":"108.5","Cell RNA - SK-MEL-30 [nTPM]":"46.3","Cell RNA - SuSa [nTPM]":"32.7","Cell RNA - T-47d [nTPM]":"58.3","Cell RNA - THP-1 [nTPM]":"4.8","Cell RNA - TIME [nTPM]":"38.8","Cell RNA - U-138 MG [nTPM]":"96.4","Cell RNA - U-2 OS [nTPM]":"86.2","Cell RNA - U-2197 [nTPM]":"42.3","Cell RNA - U-251 MG [nTPM]":"48.3","Cell RNA - U-266\/70 [nTPM]":"17.1","Cell RNA - U-266\/84 [nTPM]":"4.7","Cell RNA - U-698 [nTPM]":"8.1","Cell RNA - U-87 MG [nTPM]":"79.2","Cell RNA - U-937 [nTPM]":"30.1","Cell RNA - WM-115 [nTPM]":"38.0","Blood RNA - basophil [nTPM]":"1.4","Blood RNA - classical monocyte [nTPM]":"5.5","Blood RNA - eosinophil [nTPM]":"3.6","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"1.7","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"4.2","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"5.4","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"4.7","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"2.8","Brain RNA - amygdala [nTPM]":"39.4","Brain RNA - basal ganglia [nTPM]":"45.1","Brain RNA - cerebellum [nTPM]":"43.8","Brain RNA - cerebral cortex [nTPM]":"38.9","Brain RNA - hippocampal formation [nTPM]":"30.8","Brain RNA - hypothalamus [nTPM]":"30.7","Brain RNA - medulla oblongata [nTPM]":"62.6","Brain RNA - midbrain [nTPM]":"48.8","Brain RNA - pons [nTPM]":"50.3","Brain RNA - spinal cord [nTPM]":"47.8","Brain RNA - thalamus [nTPM]":"51.5","Brain RNA - white matter [nTPM]":"60.0","Single Cell Type RNA - Adipocytes [nTPM]":"29.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.7","Single Cell Type RNA - Astrocytes [nTPM]":"23.8","Single Cell Type RNA - B-cells [nTPM]":"1.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"11.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"9.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"20.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"10.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.7","Single Cell Type RNA - Endothelial cells [nTPM]":"35.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"3.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.3","Single Cell Type RNA - Fibroblasts [nTPM]":"11.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.8","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"20.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"31.8","Single Cell Type RNA - Hepatocytes [nTPM]":"47.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.7","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.3","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"14.4","Single Cell Type RNA - Langerhans cells [nTPM]":"7.6","Single Cell Type RNA - Late spermatids [nTPM]":"1.9","Single Cell Type RNA - Leydig cells [nTPM]":"12.5","Single Cell Type RNA - Macrophages [nTPM]":"8.7","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"7.4","Single Cell Type RNA - Muller glia cells [nTPM]":"12.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"39.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.8","Single Cell Type RNA - Paneth cells [nTPM]":"6.6","Single Cell Type RNA - Peritubular cells [nTPM]":"32.0","Single Cell Type RNA - Plasma cells [nTPM]":"3.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"1.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.5","Single Cell Type RNA - T-cells [nTPM]":"1.2","Single Cell Type RNA - Theca cells [nTPM]":"11.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.8","Single Cell Type RNA - Urothelial cells [nTPM]":"5.3"},{"Gene":"NDUFAF7","Gene synonym":["C2orf56","MidA","PRO1853"],"Ensembl":"ENSG00000003509","Gene description":"NADH:ubiquinone oxidoreductase complex assembly factor 7","Uniprot":["Q7L592"],"Chromosome":"2","Position":"37231631-37253403","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"38.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"196.6","Late spermatids":"109.6","Spermatocytes":"118.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045217"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045217":"AB_10960395"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.48e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.08e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.67e-3"},"Tissue RNA - adipose tissue [nTPM]":"6.2","Tissue RNA - adrenal gland [nTPM]":"12.7","Tissue RNA - amygdala [nTPM]":"6.7","Tissue RNA - appendix [nTPM]":"5.4","Tissue RNA - basal ganglia [nTPM]":"7.1","Tissue RNA - bone marrow [nTPM]":"6.0","Tissue RNA - breast [nTPM]":"6.0","Tissue RNA - cerebellum [nTPM]":"7.7","Tissue RNA - cerebral cortex [nTPM]":"7.8","Tissue RNA - cervix [nTPM]":"8.0","Tissue RNA - choroid plexus [nTPM]":"6.2","Tissue RNA - colon [nTPM]":"12.1","Tissue RNA - duodenum [nTPM]":"4.6","Tissue RNA - endometrium 1 [nTPM]":"7.8","Tissue RNA - epididymis [nTPM]":"8.0","Tissue RNA - esophagus [nTPM]":"5.6","Tissue RNA - fallopian tube [nTPM]":"6.0","Tissue RNA - gallbladder [nTPM]":"5.9","Tissue RNA - heart muscle [nTPM]":"15.5","Tissue RNA - hippocampal formation [nTPM]":"7.3","Tissue RNA - hypothalamus [nTPM]":"6.6","Tissue RNA - kidney [nTPM]":"9.3","Tissue RNA - liver [nTPM]":"10.6","Tissue RNA - lung [nTPM]":"5.5","Tissue RNA - lymph node [nTPM]":"6.9","Tissue RNA - medulla oblongata [nTPM]":"6.5","Tissue RNA - midbrain [nTPM]":"6.5","Tissue RNA - ovary [nTPM]":"7.0","Tissue RNA - pancreas [nTPM]":"5.7","Tissue RNA - parathyroid gland [nTPM]":"8.2","Tissue RNA - pituitary gland [nTPM]":"6.8","Tissue RNA - placenta [nTPM]":"5.9","Tissue RNA - pons [nTPM]":"6.8","Tissue RNA - prostate [nTPM]":"6.6","Tissue RNA - rectum [nTPM]":"5.9","Tissue RNA - retina [nTPM]":"10.0","Tissue RNA - salivary gland [nTPM]":"5.7","Tissue RNA - seminal vesicle [nTPM]":"5.4","Tissue RNA - skeletal muscle [nTPM]":"20.4","Tissue RNA - skin 1 [nTPM]":"4.9","Tissue RNA - small intestine [nTPM]":"5.7","Tissue RNA - smooth muscle [nTPM]":"7.3","Tissue RNA - spinal cord [nTPM]":"5.8","Tissue RNA - spleen [nTPM]":"6.6","Tissue RNA - stomach 1 [nTPM]":"6.2","Tissue RNA - testis [nTPM]":"38.8","Tissue RNA - thalamus [nTPM]":"6.2","Tissue RNA - thymus [nTPM]":"8.2","Tissue RNA - thyroid gland [nTPM]":"5.1","Tissue RNA - tongue [nTPM]":"24.4","Tissue RNA - tonsil [nTPM]":"5.9","Tissue RNA - urinary bladder [nTPM]":"6.7","Tissue RNA - vagina [nTPM]":"6.1","Tissue RNA - white matter [nTPM]":"7.1","Cell RNA - A-431 [nTPM]":"20.2","Cell RNA - A549 [nTPM]":"10.6","Cell RNA - AF22 [nTPM]":"13.2","Cell RNA - AN3-CA [nTPM]":"11.6","Cell RNA - ASC diff [nTPM]":"8.3","Cell RNA - ASC TERT1 [nTPM]":"17.6","Cell RNA - BEWO [nTPM]":"7.3","Cell RNA - BJ [nTPM]":"6.6","Cell RNA - BJ hTERT+ [nTPM]":"10.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.1","Cell RNA - CACO-2 [nTPM]":"22.9","Cell RNA - CAPAN-2 [nTPM]":"8.5","Cell RNA - Daudi [nTPM]":"17.1","Cell RNA - EFO-21 [nTPM]":"8.1","Cell RNA - fHDF\/TERT166 [nTPM]":"6.0","Cell RNA - GAMG [nTPM]":"18.9","Cell RNA - HaCaT [nTPM]":"14.8","Cell RNA - HAP1 [nTPM]":"16.2","Cell RNA - HBEC3-KT [nTPM]":"8.3","Cell RNA - HBF TERT88 [nTPM]":"13.1","Cell RNA - HDLM-2 [nTPM]":"11.9","Cell RNA - HEK 293 [nTPM]":"12.1","Cell RNA - HEL [nTPM]":"12.6","Cell RNA - HeLa [nTPM]":"13.1","Cell RNA - Hep G2 [nTPM]":"21.1","Cell RNA - HHSteC [nTPM]":"10.2","Cell RNA - HL-60 [nTPM]":"12.6","Cell RNA - HMC-1 [nTPM]":"6.1","Cell RNA - HSkMC [nTPM]":"13.8","Cell RNA - hTCEpi [nTPM]":"13.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.1","Cell RNA - hTERT-HME1 [nTPM]":"5.6","Cell RNA - hTERT-RPE1 [nTPM]":"11.8","Cell RNA - HUVEC TERT2 [nTPM]":"17.4","Cell RNA - JURKAT [nTPM]":"6.4","Cell RNA - K-562 [nTPM]":"15.5","Cell RNA - Karpas-707 [nTPM]":"11.1","Cell RNA - LHCN-M2 [nTPM]":"6.7","Cell RNA - MCF7 [nTPM]":"7.4","Cell RNA - MOLT-4 [nTPM]":"12.6","Cell RNA - NB-4 [nTPM]":"13.5","Cell RNA - NTERA-2 [nTPM]":"17.3","Cell RNA - OE19 [nTPM]":"15.9","Cell RNA - PC-3 [nTPM]":"9.5","Cell RNA - REH [nTPM]":"11.3","Cell RNA - RH-30 [nTPM]":"10.2","Cell RNA - RPMI-8226 [nTPM]":"14.4","Cell RNA - RPTEC TERT1 [nTPM]":"15.4","Cell RNA - RT4 [nTPM]":"7.4","Cell RNA - SCLC-21H [nTPM]":"13.7","Cell RNA - SH-SY5Y [nTPM]":"11.0","Cell RNA - SiHa [nTPM]":"8.2","Cell RNA - SK-BR-3 [nTPM]":"13.9","Cell RNA - SK-MEL-30 [nTPM]":"14.3","Cell RNA - SuSa [nTPM]":"18.6","Cell RNA - T-47d [nTPM]":"8.4","Cell RNA - THP-1 [nTPM]":"4.9","Cell RNA - TIME [nTPM]":"3.4","Cell RNA - U-138 MG [nTPM]":"9.2","Cell RNA - U-2 OS [nTPM]":"12.3","Cell RNA - U-2197 [nTPM]":"11.6","Cell RNA - U-251 MG [nTPM]":"12.1","Cell RNA - U-266\/70 [nTPM]":"9.7","Cell RNA - U-266\/84 [nTPM]":"6.0","Cell RNA - U-698 [nTPM]":"19.8","Cell RNA - U-87 MG [nTPM]":"13.4","Cell RNA - U-937 [nTPM]":"16.9","Cell RNA - WM-115 [nTPM]":"7.9","Blood RNA - basophil [nTPM]":"3.0","Blood RNA - classical monocyte [nTPM]":"4.3","Blood RNA - eosinophil [nTPM]":"2.6","Blood RNA - gdT-cell [nTPM]":"4.1","Blood RNA - intermediate monocyte [nTPM]":"3.7","Blood RNA - MAIT T-cell [nTPM]":"1.8","Blood RNA - memory B-cell [nTPM]":"4.7","Blood RNA - memory CD4 T-cell [nTPM]":"3.6","Blood RNA - memory CD8 T-cell [nTPM]":"3.5","Blood RNA - myeloid DC [nTPM]":"5.3","Blood RNA - naive B-cell [nTPM]":"4.1","Blood RNA - naive CD4 T-cell [nTPM]":"3.5","Blood RNA - naive CD8 T-cell [nTPM]":"3.1","Blood RNA - neutrophil [nTPM]":"2.7","Blood RNA - NK-cell [nTPM]":"4.1","Blood RNA - non-classical monocyte [nTPM]":"2.7","Blood RNA - plasmacytoid DC [nTPM]":"4.2","Blood RNA - T-reg [nTPM]":"4.6","Blood RNA - total PBMC [nTPM]":"2.0","Brain RNA - amygdala [nTPM]":"6.7","Brain RNA - basal ganglia [nTPM]":"7.1","Brain RNA - cerebellum [nTPM]":"7.7","Brain RNA - cerebral cortex [nTPM]":"7.8","Brain RNA - hippocampal formation [nTPM]":"7.3","Brain RNA - hypothalamus [nTPM]":"6.6","Brain RNA - medulla oblongata [nTPM]":"6.5","Brain RNA - midbrain [nTPM]":"6.5","Brain RNA - pons [nTPM]":"6.8","Brain RNA - spinal cord [nTPM]":"5.8","Brain RNA - thalamus [nTPM]":"6.2","Brain RNA - white matter [nTPM]":"7.1","Single Cell Type RNA - Adipocytes [nTPM]":"10.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.0","Single Cell Type RNA - Astrocytes [nTPM]":"12.7","Single Cell Type RNA - B-cells [nTPM]":"15.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"18.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"8.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.0","Single Cell Type RNA - dendritic cells [nTPM]":"16.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"10.5","Single Cell Type RNA - Early spermatids [nTPM]":"196.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.1","Single Cell Type RNA - Endothelial cells [nTPM]":"9.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"6.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"30.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.8","Single Cell Type RNA - Fibroblasts [nTPM]":"9.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.2","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"11.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"5.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.4","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"26.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.5","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"7.3","Single Cell Type RNA - Langerhans cells [nTPM]":"7.8","Single Cell Type RNA - Late spermatids [nTPM]":"109.6","Single Cell Type RNA - Leydig cells [nTPM]":"13.4","Single Cell Type RNA - Macrophages [nTPM]":"9.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"10.5","Single Cell Type RNA - Muller glia cells [nTPM]":"7.6","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.8","Single Cell Type RNA - Paneth cells [nTPM]":"2.0","Single Cell Type RNA - Peritubular cells [nTPM]":"16.6","Single Cell Type RNA - Plasma cells [nTPM]":"9.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.0","Single Cell Type RNA - Spermatocytes [nTPM]":"118.4","Single Cell Type RNA - Spermatogonia [nTPM]":"14.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.5","Single Cell Type RNA - T-cells [nTPM]":"13.6","Single Cell Type RNA - Theca cells [nTPM]":"16.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.2","Single Cell Type RNA - Urothelial cells [nTPM]":"6.3"},{"Gene":"NDUFS1","Gene synonym":["CI-75k"],"Ensembl":"ENSG00000023228","Gene description":"NADH:ubiquinone oxidoreductase core subunit S1","Uniprot":["P28331"],"Chromosome":"2","Position":"206114817-206159509","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Oxidoreductase","Translocase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"181.7","skeletal muscle":"221.6","tongue":"225.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cardiomyocytes":"582.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064605","CAB070844"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"48000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB070844":null,"HPA064605":"AB_2685297"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.85e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.63e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.47e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Tissue RNA - adipose tissue [nTPM]":"27.1","Tissue RNA - adrenal gland [nTPM]":"61.6","Tissue RNA - amygdala [nTPM]":"8.3","Tissue RNA - appendix [nTPM]":"13.3","Tissue RNA - basal ganglia [nTPM]":"10.8","Tissue RNA - bone marrow [nTPM]":"13.2","Tissue RNA - breast [nTPM]":"23.8","Tissue RNA - cerebellum [nTPM]":"14.9","Tissue RNA - cerebral cortex [nTPM]":"16.1","Tissue RNA - cervix [nTPM]":"19.5","Tissue RNA - choroid plexus [nTPM]":"39.7","Tissue RNA - colon [nTPM]":"35.3","Tissue RNA - duodenum [nTPM]":"29.9","Tissue RNA - endometrium 1 [nTPM]":"19.3","Tissue RNA - epididymis [nTPM]":"10.8","Tissue RNA - esophagus [nTPM]":"36.2","Tissue RNA - fallopian tube [nTPM]":"16.3","Tissue RNA - gallbladder [nTPM]":"10.5","Tissue RNA - heart muscle [nTPM]":"181.7","Tissue RNA - hippocampal formation [nTPM]":"10.7","Tissue RNA - hypothalamus [nTPM]":"13.7","Tissue RNA - kidney [nTPM]":"48.0","Tissue RNA - liver [nTPM]":"51.8","Tissue RNA - lung [nTPM]":"18.3","Tissue RNA - lymph node [nTPM]":"12.6","Tissue RNA - medulla oblongata [nTPM]":"10.1","Tissue RNA - midbrain [nTPM]":"10.1","Tissue RNA - ovary [nTPM]":"14.6","Tissue RNA - pancreas [nTPM]":"19.2","Tissue RNA - parathyroid gland [nTPM]":"47.2","Tissue RNA - pituitary gland [nTPM]":"20.2","Tissue RNA - placenta [nTPM]":"14.4","Tissue RNA - pons [nTPM]":"11.7","Tissue RNA - prostate [nTPM]":"15.8","Tissue RNA - rectum [nTPM]":"30.0","Tissue RNA - retina [nTPM]":"24.4","Tissue RNA - salivary gland [nTPM]":"27.7","Tissue RNA - seminal vesicle [nTPM]":"15.6","Tissue RNA - skeletal muscle [nTPM]":"221.6","Tissue RNA - skin 1 [nTPM]":"26.6","Tissue RNA - small intestine [nTPM]":"26.1","Tissue RNA - smooth muscle [nTPM]":"16.4","Tissue RNA - spinal cord [nTPM]":"9.2","Tissue RNA - spleen [nTPM]":"16.8","Tissue RNA - stomach 1 [nTPM]":"37.1","Tissue RNA - testis [nTPM]":"20.8","Tissue RNA - thalamus [nTPM]":"14.2","Tissue RNA - thymus [nTPM]":"15.6","Tissue RNA - thyroid gland [nTPM]":"17.9","Tissue RNA - tongue [nTPM]":"225.2","Tissue RNA - tonsil [nTPM]":"16.9","Tissue RNA - urinary bladder [nTPM]":"22.4","Tissue RNA - vagina [nTPM]":"22.4","Tissue RNA - white matter [nTPM]":"12.5","Cell RNA - A-431 [nTPM]":"28.3","Cell RNA - A549 [nTPM]":"27.6","Cell RNA - AF22 [nTPM]":"39.2","Cell RNA - AN3-CA [nTPM]":"28.6","Cell RNA - ASC diff [nTPM]":"35.8","Cell RNA - ASC TERT1 [nTPM]":"28.9","Cell RNA - BEWO [nTPM]":"45.4","Cell RNA - BJ [nTPM]":"40.4","Cell RNA - BJ hTERT+ [nTPM]":"43.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"66.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"47.6","Cell RNA - CACO-2 [nTPM]":"72.0","Cell RNA - CAPAN-2 [nTPM]":"32.1","Cell RNA - Daudi [nTPM]":"31.7","Cell RNA - EFO-21 [nTPM]":"34.8","Cell RNA - fHDF\/TERT166 [nTPM]":"50.8","Cell RNA - GAMG [nTPM]":"65.5","Cell RNA - HaCaT [nTPM]":"38.5","Cell RNA - HAP1 [nTPM]":"52.9","Cell RNA - HBEC3-KT [nTPM]":"39.2","Cell RNA - HBF TERT88 [nTPM]":"58.2","Cell RNA - HDLM-2 [nTPM]":"14.6","Cell RNA - HEK 293 [nTPM]":"24.9","Cell RNA - HEL [nTPM]":"63.5","Cell RNA - HeLa [nTPM]":"65.1","Cell RNA - Hep G2 [nTPM]":"64.9","Cell RNA - HHSteC [nTPM]":"37.0","Cell RNA - HL-60 [nTPM]":"46.2","Cell RNA - HMC-1 [nTPM]":"27.5","Cell RNA - HSkMC [nTPM]":"35.3","Cell RNA - hTCEpi [nTPM]":"22.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"51.9","Cell RNA - hTERT-HME1 [nTPM]":"40.4","Cell RNA - hTERT-RPE1 [nTPM]":"29.6","Cell RNA - HUVEC TERT2 [nTPM]":"52.3","Cell RNA - JURKAT [nTPM]":"39.3","Cell RNA - K-562 [nTPM]":"69.8","Cell RNA - Karpas-707 [nTPM]":"31.1","Cell RNA - LHCN-M2 [nTPM]":"43.6","Cell RNA - MCF7 [nTPM]":"35.2","Cell RNA - MOLT-4 [nTPM]":"38.5","Cell RNA - NB-4 [nTPM]":"30.7","Cell RNA - NTERA-2 [nTPM]":"36.5","Cell RNA - OE19 [nTPM]":"47.2","Cell RNA - PC-3 [nTPM]":"48.6","Cell RNA - REH [nTPM]":"38.3","Cell RNA - RH-30 [nTPM]":"54.7","Cell RNA - RPMI-8226 [nTPM]":"55.1","Cell RNA - RPTEC TERT1 [nTPM]":"54.7","Cell RNA - RT4 [nTPM]":"50.7","Cell RNA - SCLC-21H [nTPM]":"38.1","Cell RNA - SH-SY5Y [nTPM]":"29.8","Cell RNA - SiHa [nTPM]":"46.7","Cell RNA - SK-BR-3 [nTPM]":"45.1","Cell RNA - SK-MEL-30 [nTPM]":"67.1","Cell RNA - SuSa [nTPM]":"53.3","Cell RNA - T-47d [nTPM]":"39.8","Cell RNA - THP-1 [nTPM]":"44.2","Cell RNA - TIME [nTPM]":"40.1","Cell RNA - U-138 MG [nTPM]":"36.2","Cell RNA - U-2 OS [nTPM]":"32.0","Cell RNA - U-2197 [nTPM]":"35.8","Cell RNA - U-251 MG [nTPM]":"39.1","Cell RNA - U-266\/70 [nTPM]":"29.8","Cell RNA - U-266\/84 [nTPM]":"38.4","Cell RNA - U-698 [nTPM]":"46.9","Cell RNA - U-87 MG [nTPM]":"36.3","Cell RNA - U-937 [nTPM]":"37.5","Cell RNA - WM-115 [nTPM]":"37.8","Blood RNA - basophil [nTPM]":"14.1","Blood RNA - classical monocyte [nTPM]":"12.9","Blood RNA - eosinophil [nTPM]":"15.7","Blood RNA - gdT-cell [nTPM]":"12.4","Blood RNA - intermediate monocyte [nTPM]":"15.2","Blood RNA - MAIT T-cell [nTPM]":"9.6","Blood RNA - memory B-cell [nTPM]":"9.6","Blood RNA - memory CD4 T-cell [nTPM]":"10.8","Blood RNA - memory CD8 T-cell [nTPM]":"11.8","Blood RNA - myeloid DC [nTPM]":"14.7","Blood RNA - naive B-cell [nTPM]":"9.0","Blood RNA - naive CD4 T-cell [nTPM]":"9.6","Blood RNA - naive CD8 T-cell [nTPM]":"11.1","Blood RNA - neutrophil [nTPM]":"9.2","Blood RNA - NK-cell [nTPM]":"12.5","Blood RNA - non-classical monocyte [nTPM]":"22.5","Blood RNA - plasmacytoid DC [nTPM]":"7.8","Blood RNA - T-reg [nTPM]":"15.9","Blood RNA - total PBMC [nTPM]":"9.5","Brain RNA - amygdala [nTPM]":"8.3","Brain RNA - basal ganglia [nTPM]":"10.8","Brain RNA - cerebellum [nTPM]":"14.9","Brain RNA - cerebral cortex [nTPM]":"16.1","Brain RNA - hippocampal formation [nTPM]":"10.7","Brain RNA - hypothalamus [nTPM]":"13.7","Brain RNA - medulla oblongata [nTPM]":"10.1","Brain RNA - midbrain [nTPM]":"10.1","Brain RNA - pons [nTPM]":"11.7","Brain RNA - spinal cord [nTPM]":"9.2","Brain RNA - thalamus [nTPM]":"14.2","Brain RNA - white matter [nTPM]":"12.5","Single Cell Type RNA - Adipocytes [nTPM]":"32.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"33.0","Single Cell Type RNA - Astrocytes [nTPM]":"45.1","Single Cell Type RNA - B-cells [nTPM]":"23.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"40.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"30.1","Single Cell Type RNA - Bipolar cells [nTPM]":"97.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"582.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"48.6","Single Cell Type RNA - Club cells [nTPM]":"42.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"120.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"48.4","Single Cell Type RNA - dendritic cells [nTPM]":"18.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"74.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"93.9","Single Cell Type RNA - Ductal cells [nTPM]":"44.2","Single Cell Type RNA - Early spermatids [nTPM]":"14.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"49.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"49.8","Single Cell Type RNA - Endothelial cells [nTPM]":"36.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"51.0","Single Cell Type RNA - Erythroid cells [nTPM]":"42.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"67.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"28.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"33.7","Single Cell Type RNA - Fibroblasts [nTPM]":"42.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"48.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"54.5","Single Cell Type RNA - granulocytes [nTPM]":"37.3","Single Cell Type RNA - Granulosa cells [nTPM]":"42.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"29.3","Single Cell Type RNA - Hepatocytes [nTPM]":"94.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"34.0","Single Cell Type RNA - Horizontal cells [nTPM]":"117.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"72.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"47.9","Single Cell Type RNA - Ionocytes [nTPM]":"54.9","Single Cell Type RNA - Kupffer cells [nTPM]":"31.2","Single Cell Type RNA - Langerhans cells [nTPM]":"10.7","Single Cell Type RNA - Late spermatids [nTPM]":"7.0","Single Cell Type RNA - Leydig cells [nTPM]":"33.5","Single Cell Type RNA - Macrophages [nTPM]":"27.7","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"28.1","Single Cell Type RNA - monocytes [nTPM]":"37.2","Single Cell Type RNA - Muller glia cells [nTPM]":"62.7","Single Cell Type RNA - NK-cells [nTPM]":"27.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"45.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"41.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"32.1","Single Cell Type RNA - Paneth cells [nTPM]":"46.4","Single Cell Type RNA - Peritubular cells [nTPM]":"44.8","Single Cell Type RNA - Plasma cells [nTPM]":"31.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"77.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"102.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"53.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"81.5","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"55.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"60.8","Single Cell Type RNA - Spermatocytes [nTPM]":"58.2","Single Cell Type RNA - Spermatogonia [nTPM]":"49.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"40.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"52.5","Single Cell Type RNA - T-cells [nTPM]":"23.7","Single Cell Type RNA - Theca cells [nTPM]":"71.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"69.9","Single Cell Type RNA - Urothelial cells [nTPM]":"26.6"},{"Gene":"NDUFS2","Gene synonym":["CI-49"],"Ensembl":"ENSG00000158864","Gene description":"NADH:ubiquinone oxidoreductase core subunit S2","Uniprot":["O75306"],"Chromosome":"1","Position":"161197104-161214723","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Oxidoreductase","Translocase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"464.8","tongue":"633.7"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055140","HPA061953"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"25000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA055140":"AB_2682713","HPA061953":"AB_2684646"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.32e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Tissue RNA - adipose tissue [nTPM]":"60.2","Tissue RNA - adrenal gland [nTPM]":"98.2","Tissue RNA - amygdala [nTPM]":"38.7","Tissue RNA - appendix [nTPM]":"37.4","Tissue RNA - basal ganglia [nTPM]":"41.6","Tissue RNA - bone marrow [nTPM]":"39.5","Tissue RNA - breast [nTPM]":"49.6","Tissue RNA - cerebellum [nTPM]":"46.4","Tissue RNA - cerebral cortex [nTPM]":"48.8","Tissue RNA - cervix [nTPM]":"40.2","Tissue RNA - choroid plexus [nTPM]":"76.6","Tissue RNA - colon [nTPM]":"96.5","Tissue RNA - duodenum [nTPM]":"102.4","Tissue RNA - endometrium 1 [nTPM]":"41.4","Tissue RNA - epididymis [nTPM]":"33.4","Tissue RNA - esophagus [nTPM]":"62.0","Tissue RNA - fallopian tube [nTPM]":"52.5","Tissue RNA - gallbladder [nTPM]":"36.8","Tissue RNA - heart muscle [nTPM]":"273.7","Tissue RNA - hippocampal formation [nTPM]":"40.5","Tissue RNA - hypothalamus [nTPM]":"47.5","Tissue RNA - kidney [nTPM]":"137.0","Tissue RNA - liver [nTPM]":"177.4","Tissue RNA - lung [nTPM]":"48.5","Tissue RNA - lymph node [nTPM]":"42.4","Tissue RNA - medulla oblongata [nTPM]":"49.5","Tissue RNA - midbrain [nTPM]":"40.7","Tissue RNA - ovary [nTPM]":"51.6","Tissue RNA - pancreas [nTPM]":"47.7","Tissue RNA - parathyroid gland [nTPM]":"156.5","Tissue RNA - pituitary gland [nTPM]":"35.8","Tissue RNA - placenta [nTPM]":"41.6","Tissue RNA - pons [nTPM]":"53.1","Tissue RNA - prostate [nTPM]":"45.7","Tissue RNA - rectum [nTPM]":"101.8","Tissue RNA - retina [nTPM]":"36.2","Tissue RNA - salivary gland [nTPM]":"53.5","Tissue RNA - seminal vesicle [nTPM]":"49.0","Tissue RNA - skeletal muscle [nTPM]":"464.8","Tissue RNA - skin 1 [nTPM]":"51.4","Tissue RNA - small intestine [nTPM]":"81.5","Tissue RNA - smooth muscle [nTPM]":"58.6","Tissue RNA - spinal cord [nTPM]":"41.6","Tissue RNA - spleen [nTPM]":"43.6","Tissue RNA - stomach 1 [nTPM]":"73.3","Tissue RNA - testis [nTPM]":"29.5","Tissue RNA - thalamus [nTPM]":"47.9","Tissue RNA - thymus [nTPM]":"48.3","Tissue RNA - thyroid gland [nTPM]":"45.0","Tissue RNA - tongue [nTPM]":"633.7","Tissue RNA - tonsil [nTPM]":"60.1","Tissue RNA - urinary bladder [nTPM]":"57.5","Tissue RNA - vagina [nTPM]":"40.0","Tissue RNA - white matter [nTPM]":"49.2","Cell RNA - A-431 [nTPM]":"101.8","Cell RNA - A549 [nTPM]":"129.4","Cell RNA - AF22 [nTPM]":"95.2","Cell RNA - AN3-CA [nTPM]":"104.0","Cell RNA - ASC diff [nTPM]":"115.1","Cell RNA - ASC TERT1 [nTPM]":"102.8","Cell RNA - BEWO [nTPM]":"77.0","Cell RNA - BJ [nTPM]":"85.7","Cell RNA - BJ hTERT+ [nTPM]":"105.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"139.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"107.5","Cell RNA - CACO-2 [nTPM]":"143.9","Cell RNA - CAPAN-2 [nTPM]":"98.5","Cell RNA - Daudi [nTPM]":"108.4","Cell RNA - EFO-21 [nTPM]":"168.1","Cell RNA - fHDF\/TERT166 [nTPM]":"113.0","Cell RNA - GAMG [nTPM]":"81.3","Cell RNA - HaCaT [nTPM]":"135.9","Cell RNA - HAP1 [nTPM]":"129.1","Cell RNA - HBEC3-KT [nTPM]":"131.8","Cell RNA - HBF TERT88 [nTPM]":"122.1","Cell RNA - HDLM-2 [nTPM]":"84.2","Cell RNA - HEK 293 [nTPM]":"108.0","Cell RNA - HEL [nTPM]":"105.9","Cell RNA - HeLa [nTPM]":"109.5","Cell RNA - Hep G2 [nTPM]":"136.5","Cell RNA - HHSteC [nTPM]":"117.7","Cell RNA - HL-60 [nTPM]":"116.0","Cell RNA - HMC-1 [nTPM]":"105.3","Cell RNA - HSkMC [nTPM]":"147.2","Cell RNA - hTCEpi [nTPM]":"112.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"121.1","Cell RNA - hTERT-HME1 [nTPM]":"137.2","Cell RNA - hTERT-RPE1 [nTPM]":"96.8","Cell RNA - HUVEC TERT2 [nTPM]":"160.5","Cell RNA - JURKAT [nTPM]":"115.4","Cell RNA - K-562 [nTPM]":"139.9","Cell RNA - Karpas-707 [nTPM]":"72.7","Cell RNA - LHCN-M2 [nTPM]":"132.5","Cell RNA - MCF7 [nTPM]":"93.5","Cell RNA - MOLT-4 [nTPM]":"81.7","Cell RNA - NB-4 [nTPM]":"58.4","Cell RNA - NTERA-2 [nTPM]":"175.3","Cell RNA - OE19 [nTPM]":"288.5","Cell RNA - PC-3 [nTPM]":"116.5","Cell RNA - REH [nTPM]":"72.0","Cell RNA - RH-30 [nTPM]":"83.3","Cell RNA - RPMI-8226 [nTPM]":"172.0","Cell RNA - RPTEC TERT1 [nTPM]":"157.8","Cell RNA - RT4 [nTPM]":"109.4","Cell RNA - SCLC-21H [nTPM]":"97.2","Cell RNA - SH-SY5Y [nTPM]":"152.0","Cell RNA - SiHa [nTPM]":"93.0","Cell RNA - SK-BR-3 [nTPM]":"237.0","Cell RNA - SK-MEL-30 [nTPM]":"151.5","Cell RNA - SuSa [nTPM]":"116.4","Cell RNA - T-47d [nTPM]":"221.7","Cell RNA - THP-1 [nTPM]":"342.2","Cell RNA - TIME [nTPM]":"108.6","Cell RNA - U-138 MG [nTPM]":"84.5","Cell RNA - U-2 OS [nTPM]":"66.3","Cell RNA - U-2197 [nTPM]":"65.5","Cell RNA - U-251 MG [nTPM]":"123.7","Cell RNA - U-266\/70 [nTPM]":"125.2","Cell RNA - U-266\/84 [nTPM]":"172.0","Cell RNA - U-698 [nTPM]":"95.1","Cell RNA - U-87 MG [nTPM]":"123.6","Cell RNA - U-937 [nTPM]":"109.3","Cell RNA - WM-115 [nTPM]":"105.4","Blood RNA - basophil [nTPM]":"150.0","Blood RNA - classical monocyte [nTPM]":"159.3","Blood RNA - eosinophil [nTPM]":"85.7","Blood RNA - gdT-cell [nTPM]":"82.0","Blood RNA - intermediate monocyte [nTPM]":"193.2","Blood RNA - MAIT T-cell [nTPM]":"82.6","Blood RNA - memory B-cell [nTPM]":"81.4","Blood RNA - memory CD4 T-cell [nTPM]":"86.6","Blood RNA - memory CD8 T-cell [nTPM]":"86.3","Blood RNA - myeloid DC [nTPM]":"217.8","Blood RNA - naive B-cell [nTPM]":"68.4","Blood RNA - naive CD4 T-cell [nTPM]":"86.6","Blood RNA - naive CD8 T-cell [nTPM]":"88.1","Blood RNA - neutrophil [nTPM]":"86.7","Blood RNA - NK-cell [nTPM]":"93.5","Blood RNA - non-classical monocyte [nTPM]":"190.7","Blood RNA - plasmacytoid DC [nTPM]":"128.7","Blood RNA - T-reg [nTPM]":"130.8","Blood RNA - total PBMC [nTPM]":"167.5","Brain RNA - amygdala [nTPM]":"38.7","Brain RNA - basal ganglia [nTPM]":"41.6","Brain RNA - cerebellum [nTPM]":"46.4","Brain RNA - cerebral cortex [nTPM]":"48.8","Brain RNA - hippocampal formation [nTPM]":"40.5","Brain RNA - hypothalamus [nTPM]":"47.5","Brain RNA - medulla oblongata [nTPM]":"49.5","Brain RNA - midbrain [nTPM]":"40.7","Brain RNA - pons [nTPM]":"53.1","Brain RNA - spinal cord [nTPM]":"41.6","Brain RNA - thalamus [nTPM]":"47.9","Brain RNA - white matter [nTPM]":"49.2","Single Cell Type RNA - Adipocytes [nTPM]":"70.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"45.7","Single Cell Type RNA - Astrocytes [nTPM]":"30.7","Single Cell Type RNA - B-cells [nTPM]":"47.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"38.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"52.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"277.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"52.9","Single Cell Type RNA - Bipolar cells [nTPM]":"74.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"58.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"50.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"232.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"74.4","Single Cell Type RNA - Club cells [nTPM]":"148.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"77.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"146.8","Single Cell Type RNA - dendritic cells [nTPM]":"47.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"187.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"332.6","Single Cell Type RNA - Ductal cells [nTPM]":"184.3","Single Cell Type RNA - Early spermatids [nTPM]":"11.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"43.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"57.0","Single Cell Type RNA - Endothelial cells [nTPM]":"67.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"72.0","Single Cell Type RNA - Erythroid cells [nTPM]":"78.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"28.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"143.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"111.3","Single Cell Type RNA - Fibroblasts [nTPM]":"69.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"80.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"41.3","Single Cell Type RNA - granulocytes [nTPM]":"69.7","Single Cell Type RNA - Granulosa cells [nTPM]":"99.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"65.7","Single Cell Type RNA - Hepatocytes [nTPM]":"206.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"150.5","Single Cell Type RNA - Horizontal cells [nTPM]":"92.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"30.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"122.6","Single Cell Type RNA - Ionocytes [nTPM]":"242.1","Single Cell Type RNA - Kupffer cells [nTPM]":"87.8","Single Cell Type RNA - Langerhans cells [nTPM]":"42.0","Single Cell Type RNA - Late spermatids [nTPM]":"7.8","Single Cell Type RNA - Leydig cells [nTPM]":"43.5","Single Cell Type RNA - Macrophages [nTPM]":"66.5","Single Cell Type RNA - Melanocytes [nTPM]":"83.6","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"97.9","Single Cell Type RNA - Muller glia cells [nTPM]":"57.0","Single Cell Type RNA - NK-cells [nTPM]":"35.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"48.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"147.7","Single Cell Type RNA - Paneth cells [nTPM]":"105.1","Single Cell Type RNA - Peritubular cells [nTPM]":"33.4","Single Cell Type RNA - Plasma cells [nTPM]":"49.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"25.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"221.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"345.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"103.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"57.3","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"41.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"176.6","Single Cell Type RNA - Spermatocytes [nTPM]":"42.0","Single Cell Type RNA - Spermatogonia [nTPM]":"27.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"68.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"43.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"158.4","Single Cell Type RNA - T-cells [nTPM]":"50.0","Single Cell Type RNA - Theca cells [nTPM]":"192.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"172.5","Single Cell Type RNA - Urothelial cells [nTPM]":"57.5"},{"Gene":"NDUFS3","Gene synonym":["CI-30"],"Ensembl":"ENSG00000213619","Gene description":"NADH:ubiquinone oxidoreductase core subunit S3","Uniprot":["O75489"],"Chromosome":"11","Position":"47565336-47584562","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Oxidoreductase","Translocase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"292.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"405.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004484","CAB034894"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"14000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"CAB034894":"AB_2151118","HPA004484":"AB_1079464"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.61e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-3"},"Tissue RNA - adipose tissue [nTPM]":"52.4","Tissue RNA - adrenal gland [nTPM]":"91.3","Tissue RNA - amygdala [nTPM]":"47.4","Tissue RNA - appendix [nTPM]":"16.5","Tissue RNA - basal ganglia [nTPM]":"52.6","Tissue RNA - bone marrow [nTPM]":"44.1","Tissue RNA - breast [nTPM]":"50.7","Tissue RNA - cerebellum [nTPM]":"55.6","Tissue RNA - cerebral cortex [nTPM]":"50.2","Tissue RNA - cervix [nTPM]":"43.5","Tissue RNA - choroid plexus [nTPM]":"59.4","Tissue RNA - colon [nTPM]":"97.5","Tissue RNA - duodenum [nTPM]":"53.8","Tissue RNA - endometrium 1 [nTPM]":"49.7","Tissue RNA - epididymis [nTPM]":"26.2","Tissue RNA - esophagus [nTPM]":"78.7","Tissue RNA - fallopian tube [nTPM]":"42.6","Tissue RNA - gallbladder [nTPM]":"18.1","Tissue RNA - heart muscle [nTPM]":"210.3","Tissue RNA - hippocampal formation [nTPM]":"49.3","Tissue RNA - hypothalamus [nTPM]":"51.9","Tissue RNA - kidney [nTPM]":"94.2","Tissue RNA - liver [nTPM]":"96.2","Tissue RNA - lung [nTPM]":"40.5","Tissue RNA - lymph node [nTPM]":"25.5","Tissue RNA - medulla oblongata [nTPM]":"48.8","Tissue RNA - midbrain [nTPM]":"49.3","Tissue RNA - ovary [nTPM]":"37.3","Tissue RNA - pancreas [nTPM]":"56.7","Tissue RNA - parathyroid gland [nTPM]":"53.6","Tissue RNA - pituitary gland [nTPM]":"67.5","Tissue RNA - placenta [nTPM]":"17.6","Tissue RNA - pons [nTPM]":"49.4","Tissue RNA - prostate [nTPM]":"44.0","Tissue RNA - rectum [nTPM]":"52.7","Tissue RNA - retina [nTPM]":"23.5","Tissue RNA - salivary gland [nTPM]":"60.9","Tissue RNA - seminal vesicle [nTPM]":"27.5","Tissue RNA - skeletal muscle [nTPM]":"292.3","Tissue RNA - skin 1 [nTPM]":"66.2","Tissue RNA - small intestine [nTPM]":"69.4","Tissue RNA - smooth muscle [nTPM]":"26.6","Tissue RNA - spinal cord [nTPM]":"50.3","Tissue RNA - spleen [nTPM]":"55.5","Tissue RNA - stomach 1 [nTPM]":"81.4","Tissue RNA - testis [nTPM]":"48.2","Tissue RNA - thalamus [nTPM]":"54.7","Tissue RNA - thymus [nTPM]":"33.8","Tissue RNA - thyroid gland [nTPM]":"49.7","Tissue RNA - tongue [nTPM]":"194.2","Tissue RNA - tonsil [nTPM]":"33.3","Tissue RNA - urinary bladder [nTPM]":"51.4","Tissue RNA - vagina [nTPM]":"52.0","Tissue RNA - white matter [nTPM]":"47.7","Cell RNA - A-431 [nTPM]":"37.7","Cell RNA - A549 [nTPM]":"68.7","Cell RNA - AF22 [nTPM]":"59.8","Cell RNA - AN3-CA [nTPM]":"62.9","Cell RNA - ASC diff [nTPM]":"48.8","Cell RNA - ASC TERT1 [nTPM]":"52.3","Cell RNA - BEWO [nTPM]":"48.2","Cell RNA - BJ [nTPM]":"35.0","Cell RNA - BJ hTERT+ [nTPM]":"60.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"84.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"80.4","Cell RNA - CACO-2 [nTPM]":"103.6","Cell RNA - CAPAN-2 [nTPM]":"65.1","Cell RNA - Daudi [nTPM]":"81.8","Cell RNA - EFO-21 [nTPM]":"34.8","Cell RNA - fHDF\/TERT166 [nTPM]":"49.7","Cell RNA - GAMG [nTPM]":"63.0","Cell RNA - HaCaT [nTPM]":"64.9","Cell RNA - HAP1 [nTPM]":"81.7","Cell RNA - HBEC3-KT [nTPM]":"61.8","Cell RNA - HBF TERT88 [nTPM]":"69.4","Cell RNA - HDLM-2 [nTPM]":"44.2","Cell RNA - HEK 293 [nTPM]":"137.2","Cell RNA - HEL [nTPM]":"49.5","Cell RNA - HeLa [nTPM]":"90.6","Cell RNA - Hep G2 [nTPM]":"106.5","Cell RNA - HHSteC [nTPM]":"49.7","Cell RNA - HL-60 [nTPM]":"121.5","Cell RNA - HMC-1 [nTPM]":"62.1","Cell RNA - HSkMC [nTPM]":"50.1","Cell RNA - hTCEpi [nTPM]":"46.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.0","Cell RNA - hTERT-HME1 [nTPM]":"52.2","Cell RNA - hTERT-RPE1 [nTPM]":"37.5","Cell RNA - HUVEC TERT2 [nTPM]":"55.3","Cell RNA - JURKAT [nTPM]":"69.2","Cell RNA - K-562 [nTPM]":"73.7","Cell RNA - Karpas-707 [nTPM]":"57.1","Cell RNA - LHCN-M2 [nTPM]":"57.7","Cell RNA - MCF7 [nTPM]":"118.6","Cell RNA - MOLT-4 [nTPM]":"87.0","Cell RNA - NB-4 [nTPM]":"164.9","Cell RNA - NTERA-2 [nTPM]":"83.6","Cell RNA - OE19 [nTPM]":"109.6","Cell RNA - PC-3 [nTPM]":"97.7","Cell RNA - REH [nTPM]":"100.7","Cell RNA - RH-30 [nTPM]":"81.8","Cell RNA - RPMI-8226 [nTPM]":"68.7","Cell RNA - RPTEC TERT1 [nTPM]":"76.4","Cell RNA - RT4 [nTPM]":"60.2","Cell RNA - SCLC-21H [nTPM]":"63.9","Cell RNA - SH-SY5Y [nTPM]":"47.1","Cell RNA - SiHa [nTPM]":"43.4","Cell RNA - SK-BR-3 [nTPM]":"76.9","Cell RNA - SK-MEL-30 [nTPM]":"83.5","Cell RNA - SuSa [nTPM]":"35.2","Cell RNA - T-47d [nTPM]":"84.4","Cell RNA - THP-1 [nTPM]":"118.2","Cell RNA - TIME [nTPM]":"37.0","Cell RNA - U-138 MG [nTPM]":"49.3","Cell RNA - U-2 OS [nTPM]":"56.4","Cell RNA - U-2197 [nTPM]":"57.0","Cell RNA - U-251 MG [nTPM]":"80.4","Cell RNA - U-266\/70 [nTPM]":"61.2","Cell RNA - U-266\/84 [nTPM]":"93.5","Cell RNA - U-698 [nTPM]":"91.8","Cell RNA - U-87 MG [nTPM]":"50.1","Cell RNA - U-937 [nTPM]":"94.9","Cell RNA - WM-115 [nTPM]":"51.3","Blood RNA - basophil [nTPM]":"38.3","Blood RNA - classical monocyte [nTPM]":"69.3","Blood RNA - eosinophil [nTPM]":"48.9","Blood RNA - gdT-cell [nTPM]":"43.2","Blood RNA - intermediate monocyte [nTPM]":"79.8","Blood RNA - MAIT T-cell [nTPM]":"46.4","Blood RNA - memory B-cell [nTPM]":"60.6","Blood RNA - memory CD4 T-cell [nTPM]":"45.2","Blood RNA - memory CD8 T-cell [nTPM]":"47.5","Blood RNA - myeloid DC [nTPM]":"83.3","Blood RNA - naive B-cell [nTPM]":"59.2","Blood RNA - naive CD4 T-cell [nTPM]":"42.4","Blood RNA - naive CD8 T-cell [nTPM]":"46.0","Blood RNA - neutrophil [nTPM]":"18.4","Blood RNA - NK-cell [nTPM]":"45.6","Blood RNA - non-classical monocyte [nTPM]":"66.7","Blood RNA - plasmacytoid DC [nTPM]":"89.3","Blood RNA - T-reg [nTPM]":"61.3","Blood RNA - total PBMC [nTPM]":"90.3","Brain RNA - amygdala [nTPM]":"47.4","Brain RNA - basal ganglia [nTPM]":"52.6","Brain RNA - cerebellum [nTPM]":"55.6","Brain RNA - cerebral cortex [nTPM]":"50.2","Brain RNA - hippocampal formation [nTPM]":"49.3","Brain RNA - hypothalamus [nTPM]":"51.9","Brain RNA - medulla oblongata [nTPM]":"48.8","Brain RNA - midbrain [nTPM]":"49.3","Brain RNA - pons [nTPM]":"49.4","Brain RNA - spinal cord [nTPM]":"50.3","Brain RNA - thalamus [nTPM]":"54.7","Brain RNA - white matter [nTPM]":"47.7","Single Cell Type RNA - Adipocytes [nTPM]":"54.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"54.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"42.6","Single Cell Type RNA - Astrocytes [nTPM]":"23.5","Single Cell Type RNA - B-cells [nTPM]":"54.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"65.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"67.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"217.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"62.6","Single Cell Type RNA - Bipolar cells [nTPM]":"45.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"60.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"72.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"176.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"81.5","Single Cell Type RNA - Club cells [nTPM]":"108.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"69.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"122.0","Single Cell Type RNA - dendritic cells [nTPM]":"70.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"183.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"405.0","Single Cell Type RNA - Ductal cells [nTPM]":"113.0","Single Cell Type RNA - Early spermatids [nTPM]":"132.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"56.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"58.6","Single Cell Type RNA - Endothelial cells [nTPM]":"60.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"84.7","Single Cell Type RNA - Erythroid cells [nTPM]":"73.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"111.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"116.5","Single Cell Type RNA - Fibroblasts [nTPM]":"60.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"81.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"40.5","Single Cell Type RNA - granulocytes [nTPM]":"57.7","Single Cell Type RNA - Granulosa cells [nTPM]":"67.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"58.5","Single Cell Type RNA - Hepatocytes [nTPM]":"126.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"195.9","Single Cell Type RNA - Horizontal cells [nTPM]":"60.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"162.8","Single Cell Type RNA - Ionocytes [nTPM]":"173.0","Single Cell Type RNA - Kupffer cells [nTPM]":"66.9","Single Cell Type RNA - Langerhans cells [nTPM]":"59.3","Single Cell Type RNA - Late spermatids [nTPM]":"63.2","Single Cell Type RNA - Leydig cells [nTPM]":"67.4","Single Cell Type RNA - Macrophages [nTPM]":"62.8","Single Cell Type RNA - Melanocytes [nTPM]":"119.2","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"83.9","Single Cell Type RNA - Muller glia cells [nTPM]":"117.9","Single Cell Type RNA - NK-cells [nTPM]":"58.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"13.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"91.7","Single Cell Type RNA - Paneth cells [nTPM]":"109.3","Single Cell Type RNA - Peritubular cells [nTPM]":"69.2","Single Cell Type RNA - Plasma cells [nTPM]":"69.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"53.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"257.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"297.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"109.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"59.5","Single Cell Type RNA - Sertoli cells [nTPM]":"105.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"55.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"154.8","Single Cell Type RNA - Spermatocytes [nTPM]":"85.5","Single Cell Type RNA - Spermatogonia [nTPM]":"74.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"115.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"75.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"89.1","Single Cell Type RNA - T-cells [nTPM]":"55.5","Single Cell Type RNA - Theca cells [nTPM]":"128.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"210.7","Single Cell Type RNA - Urothelial cells [nTPM]":"85.3"},{"Gene":"NDUFS7","Gene synonym":["CI-20","FLJ45860","FLJ46880","PSST"],"Ensembl":"ENSG00000115286","Gene description":"NADH:ubiquinone oxidoreductase core subunit S7","Uniprot":["O75251"],"Chromosome":"19","Position":"1383527-1395589","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Oxidoreductase","Translocase"],"Disease involvement":["Disease variant","Leigh syndrome","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"665.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"812.0","Proximal tubular cells":"774.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.03e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.90e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Tissue RNA - adipose tissue [nTPM]":"52.9","Tissue RNA - adrenal gland [nTPM]":"51.3","Tissue RNA - amygdala [nTPM]":"78.2","Tissue RNA - appendix [nTPM]":"31.2","Tissue RNA - basal ganglia [nTPM]":"96.8","Tissue RNA - bone marrow [nTPM]":"33.8","Tissue RNA - breast [nTPM]":"33.8","Tissue RNA - cerebellum [nTPM]":"116.0","Tissue RNA - cerebral cortex [nTPM]":"120.6","Tissue RNA - cervix [nTPM]":"32.1","Tissue RNA - choroid plexus [nTPM]":"86.6","Tissue RNA - colon [nTPM]":"50.0","Tissue RNA - duodenum [nTPM]":"104.2","Tissue RNA - endometrium 1 [nTPM]":"31.2","Tissue RNA - epididymis [nTPM]":"5.2","Tissue RNA - esophagus [nTPM]":"62.2","Tissue RNA - fallopian tube [nTPM]":"28.8","Tissue RNA - gallbladder [nTPM]":"17.6","Tissue RNA - heart muscle [nTPM]":"170.7","Tissue RNA - hippocampal formation [nTPM]":"72.6","Tissue RNA - hypothalamus [nTPM]":"92.3","Tissue RNA - kidney [nTPM]":"67.9","Tissue RNA - liver [nTPM]":"68.2","Tissue RNA - lung [nTPM]":"30.2","Tissue RNA - lymph node [nTPM]":"36.7","Tissue RNA - medulla oblongata [nTPM]":"103.6","Tissue RNA - midbrain [nTPM]":"85.5","Tissue RNA - ovary [nTPM]":"31.7","Tissue RNA - pancreas [nTPM]":"89.6","Tissue RNA - parathyroid gland [nTPM]":"43.9","Tissue RNA - pituitary gland [nTPM]":"50.2","Tissue RNA - placenta [nTPM]":"19.9","Tissue RNA - pons [nTPM]":"108.2","Tissue RNA - prostate [nTPM]":"34.1","Tissue RNA - rectum [nTPM]":"9.8","Tissue RNA - retina [nTPM]":"5.7","Tissue RNA - salivary gland [nTPM]":"75.6","Tissue RNA - seminal vesicle [nTPM]":"26.3","Tissue RNA - skeletal muscle [nTPM]":"665.9","Tissue RNA - skin 1 [nTPM]":"37.9","Tissue RNA - small intestine [nTPM]":"73.8","Tissue RNA - smooth muscle [nTPM]":"10.5","Tissue RNA - spinal cord [nTPM]":"95.6","Tissue RNA - spleen [nTPM]":"41.8","Tissue RNA - stomach 1 [nTPM]":"53.0","Tissue RNA - testis [nTPM]":"58.9","Tissue RNA - thalamus [nTPM]":"88.5","Tissue RNA - thymus [nTPM]":"19.3","Tissue RNA - thyroid gland [nTPM]":"32.1","Tissue RNA - tongue [nTPM]":"159.4","Tissue RNA - tonsil [nTPM]":"11.4","Tissue RNA - urinary bladder [nTPM]":"36.7","Tissue RNA - vagina [nTPM]":"37.7","Tissue RNA - white matter [nTPM]":"120.2","Cell RNA - A-431 [nTPM]":"127.0","Cell RNA - A549 [nTPM]":"109.3","Cell RNA - AF22 [nTPM]":"17.5","Cell RNA - AN3-CA [nTPM]":"77.6","Cell RNA - ASC diff [nTPM]":"16.0","Cell RNA - ASC TERT1 [nTPM]":"20.3","Cell RNA - BEWO [nTPM]":"68.8","Cell RNA - BJ [nTPM]":"52.0","Cell RNA - BJ hTERT+ [nTPM]":"19.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"39.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"39.0","Cell RNA - CACO-2 [nTPM]":"155.3","Cell RNA - CAPAN-2 [nTPM]":"52.8","Cell RNA - Daudi [nTPM]":"146.2","Cell RNA - EFO-21 [nTPM]":"71.4","Cell RNA - fHDF\/TERT166 [nTPM]":"13.0","Cell RNA - GAMG [nTPM]":"9.7","Cell RNA - HaCaT [nTPM]":"85.4","Cell RNA - HAP1 [nTPM]":"17.3","Cell RNA - HBEC3-KT [nTPM]":"44.1","Cell RNA - HBF TERT88 [nTPM]":"1.0","Cell RNA - HDLM-2 [nTPM]":"157.6","Cell RNA - HEK 293 [nTPM]":"143.2","Cell RNA - HEL [nTPM]":"47.0","Cell RNA - HeLa [nTPM]":"113.1","Cell RNA - Hep G2 [nTPM]":"125.7","Cell RNA - HHSteC [nTPM]":"53.4","Cell RNA - HL-60 [nTPM]":"76.5","Cell RNA - HMC-1 [nTPM]":"90.1","Cell RNA - HSkMC [nTPM]":"27.2","Cell RNA - hTCEpi [nTPM]":"47.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"17.7","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"13.2","Cell RNA - HUVEC TERT2 [nTPM]":"40.2","Cell RNA - JURKAT [nTPM]":"110.5","Cell RNA - K-562 [nTPM]":"103.1","Cell RNA - Karpas-707 [nTPM]":"196.6","Cell RNA - LHCN-M2 [nTPM]":"13.6","Cell RNA - MCF7 [nTPM]":"130.0","Cell RNA - MOLT-4 [nTPM]":"138.6","Cell RNA - NB-4 [nTPM]":"77.0","Cell RNA - NTERA-2 [nTPM]":"67.5","Cell RNA - OE19 [nTPM]":"40.8","Cell RNA - PC-3 [nTPM]":"141.0","Cell RNA - REH [nTPM]":"144.6","Cell RNA - RH-30 [nTPM]":"36.3","Cell RNA - RPMI-8226 [nTPM]":"254.9","Cell RNA - RPTEC TERT1 [nTPM]":"23.6","Cell RNA - RT4 [nTPM]":"86.9","Cell RNA - SCLC-21H [nTPM]":"105.7","Cell RNA - SH-SY5Y [nTPM]":"89.5","Cell RNA - SiHa [nTPM]":"48.5","Cell RNA - SK-BR-3 [nTPM]":"117.8","Cell RNA - SK-MEL-30 [nTPM]":"158.6","Cell RNA - SuSa [nTPM]":"2.1","Cell RNA - T-47d [nTPM]":"84.0","Cell RNA - THP-1 [nTPM]":"118.1","Cell RNA - TIME [nTPM]":"72.3","Cell RNA - U-138 MG [nTPM]":"67.3","Cell RNA - U-2 OS [nTPM]":"49.5","Cell RNA - U-2197 [nTPM]":"85.5","Cell RNA - U-251 MG [nTPM]":"100.0","Cell RNA - U-266\/70 [nTPM]":"326.9","Cell RNA - U-266\/84 [nTPM]":"218.4","Cell RNA - U-698 [nTPM]":"121.5","Cell RNA - U-87 MG [nTPM]":"110.9","Cell RNA - U-937 [nTPM]":"159.0","Cell RNA - WM-115 [nTPM]":"70.4","Blood RNA - basophil [nTPM]":"176.5","Blood RNA - classical monocyte [nTPM]":"299.0","Blood RNA - eosinophil [nTPM]":"143.8","Blood RNA - gdT-cell [nTPM]":"166.6","Blood RNA - intermediate monocyte [nTPM]":"342.4","Blood RNA - MAIT T-cell [nTPM]":"147.5","Blood RNA - memory B-cell [nTPM]":"249.4","Blood RNA - memory CD4 T-cell [nTPM]":"161.6","Blood RNA - memory CD8 T-cell [nTPM]":"159.7","Blood RNA - myeloid DC [nTPM]":"354.9","Blood RNA - naive B-cell [nTPM]":"235.6","Blood RNA - naive CD4 T-cell [nTPM]":"151.8","Blood RNA - naive CD8 T-cell [nTPM]":"146.9","Blood RNA - neutrophil [nTPM]":"75.6","Blood RNA - NK-cell [nTPM]":"160.6","Blood RNA - non-classical monocyte [nTPM]":"308.0","Blood RNA - plasmacytoid DC [nTPM]":"276.8","Blood RNA - T-reg [nTPM]":"241.8","Blood RNA - total PBMC [nTPM]":"193.2","Brain RNA - amygdala [nTPM]":"78.2","Brain RNA - basal ganglia [nTPM]":"96.8","Brain RNA - cerebellum [nTPM]":"116.0","Brain RNA - cerebral cortex [nTPM]":"120.6","Brain RNA - hippocampal formation [nTPM]":"72.6","Brain RNA - hypothalamus [nTPM]":"92.3","Brain RNA - medulla oblongata [nTPM]":"103.6","Brain RNA - midbrain [nTPM]":"85.5","Brain RNA - pons [nTPM]":"108.2","Brain RNA - spinal cord [nTPM]":"95.6","Brain RNA - thalamus [nTPM]":"88.5","Brain RNA - white matter [nTPM]":"120.2","Single Cell Type RNA - Adipocytes [nTPM]":"98.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"80.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"92.5","Single Cell Type RNA - Astrocytes [nTPM]":"14.0","Single Cell Type RNA - B-cells [nTPM]":"117.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"89.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"98.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"275.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"100.2","Single Cell Type RNA - Bipolar cells [nTPM]":"74.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"116.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"146.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"77.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"158.7","Single Cell Type RNA - Club cells [nTPM]":"167.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"145.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"50.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"225.2","Single Cell Type RNA - dendritic cells [nTPM]":"75.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"482.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"812.0","Single Cell Type RNA - Ductal cells [nTPM]":"161.8","Single Cell Type RNA - Early spermatids [nTPM]":"443.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"69.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"74.2","Single Cell Type RNA - Endothelial cells [nTPM]":"88.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"175.4","Single Cell Type RNA - Erythroid cells [nTPM]":"94.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"163.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"197.1","Single Cell Type RNA - Fibroblasts [nTPM]":"92.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"162.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"66.2","Single Cell Type RNA - granulocytes [nTPM]":"111.7","Single Cell Type RNA - Granulosa cells [nTPM]":"99.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"72.5","Single Cell Type RNA - Hepatocytes [nTPM]":"243.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"333.4","Single Cell Type RNA - Horizontal cells [nTPM]":"52.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"332.9","Single Cell Type RNA - Ionocytes [nTPM]":"248.2","Single Cell Type RNA - Kupffer cells [nTPM]":"188.4","Single Cell Type RNA - Langerhans cells [nTPM]":"129.7","Single Cell Type RNA - Late spermatids [nTPM]":"414.5","Single Cell Type RNA - Leydig cells [nTPM]":"83.9","Single Cell Type RNA - Macrophages [nTPM]":"154.6","Single Cell Type RNA - Melanocytes [nTPM]":"261.5","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"182.1","Single Cell Type RNA - Muller glia cells [nTPM]":"111.2","Single Cell Type RNA - NK-cells [nTPM]":"111.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"57.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"121.1","Single Cell Type RNA - Paneth cells [nTPM]":"346.7","Single Cell Type RNA - Peritubular cells [nTPM]":"74.1","Single Cell Type RNA - Plasma cells [nTPM]":"155.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"81.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"616.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"774.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"122.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"81.9","Single Cell Type RNA - Sertoli cells [nTPM]":"72.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"105.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"120.2","Single Cell Type RNA - Spermatocytes [nTPM]":"268.8","Single Cell Type RNA - Spermatogonia [nTPM]":"134.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"266.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"106.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"186.8","Single Cell Type RNA - T-cells [nTPM]":"100.9","Single Cell Type RNA - Theca cells [nTPM]":"128.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"410.8","Single Cell Type RNA - Urothelial cells [nTPM]":"138.7"},{"Gene":"NDUFS8","Gene synonym":["CI-23k","TYKY"],"Ensembl":"ENSG00000110717","Gene description":"NADH:ubiquinone oxidoreductase core subunit S8","Uniprot":["O00217"],"Chromosome":"11","Position":"68030617-68036644","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Oxidoreductase","Translocase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"833.5","Late spermatids":"797.2","Proximal tubular cells":"927.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018524","HPA067429"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA018524":"AB_1854355","HPA067429":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.27e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.45e-2"},"Tissue RNA - adipose tissue [nTPM]":"99.2","Tissue RNA - adrenal gland [nTPM]":"308.4","Tissue RNA - amygdala [nTPM]":"141.2","Tissue RNA - appendix [nTPM]":"38.8","Tissue RNA - basal ganglia [nTPM]":"153.2","Tissue RNA - bone marrow [nTPM]":"56.2","Tissue RNA - breast [nTPM]":"87.7","Tissue RNA - cerebellum [nTPM]":"157.2","Tissue RNA - cerebral cortex [nTPM]":"180.4","Tissue RNA - cervix [nTPM]":"73.2","Tissue RNA - choroid plexus [nTPM]":"172.3","Tissue RNA - colon [nTPM]":"142.0","Tissue RNA - duodenum [nTPM]":"81.4","Tissue RNA - endometrium 1 [nTPM]":"89.2","Tissue RNA - epididymis [nTPM]":"27.2","Tissue RNA - esophagus [nTPM]":"115.3","Tissue RNA - fallopian tube [nTPM]":"81.3","Tissue RNA - gallbladder [nTPM]":"29.1","Tissue RNA - heart muscle [nTPM]":"468.2","Tissue RNA - hippocampal formation [nTPM]":"144.2","Tissue RNA - hypothalamus [nTPM]":"152.0","Tissue RNA - kidney [nTPM]":"188.6","Tissue RNA - liver [nTPM]":"152.0","Tissue RNA - lung [nTPM]":"73.1","Tissue RNA - lymph node [nTPM]":"42.2","Tissue RNA - medulla oblongata [nTPM]":"149.6","Tissue RNA - midbrain [nTPM]":"144.9","Tissue RNA - ovary [nTPM]":"68.2","Tissue RNA - pancreas [nTPM]":"97.7","Tissue RNA - parathyroid gland [nTPM]":"74.6","Tissue RNA - pituitary gland [nTPM]":"130.6","Tissue RNA - placenta [nTPM]":"33.6","Tissue RNA - pons [nTPM]":"145.8","Tissue RNA - prostate [nTPM]":"118.2","Tissue RNA - rectum [nTPM]":"36.7","Tissue RNA - retina [nTPM]":"49.5","Tissue RNA - salivary gland [nTPM]":"96.2","Tissue RNA - seminal vesicle [nTPM]":"66.7","Tissue RNA - skeletal muscle [nTPM]":"406.4","Tissue RNA - skin 1 [nTPM]":"93.0","Tissue RNA - small intestine [nTPM]":"84.4","Tissue RNA - smooth muscle [nTPM]":"39.0","Tissue RNA - spinal cord [nTPM]":"142.2","Tissue RNA - spleen [nTPM]":"76.9","Tissue RNA - stomach 1 [nTPM]":"137.8","Tissue RNA - testis [nTPM]":"104.7","Tissue RNA - thalamus [nTPM]":"154.0","Tissue RNA - thymus [nTPM]":"40.3","Tissue RNA - thyroid gland [nTPM]":"101.8","Tissue RNA - tongue [nTPM]":"275.5","Tissue RNA - tonsil [nTPM]":"30.1","Tissue RNA - urinary bladder [nTPM]":"94.4","Tissue RNA - vagina [nTPM]":"76.0","Tissue RNA - white matter [nTPM]":"150.2","Cell RNA - A-431 [nTPM]":"152.9","Cell RNA - A549 [nTPM]":"366.4","Cell RNA - AF22 [nTPM]":"94.6","Cell RNA - AN3-CA [nTPM]":"137.0","Cell RNA - ASC diff [nTPM]":"70.9","Cell RNA - ASC TERT1 [nTPM]":"63.5","Cell RNA - BEWO [nTPM]":"132.4","Cell RNA - BJ [nTPM]":"102.3","Cell RNA - BJ hTERT+ [nTPM]":"88.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"155.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"118.9","Cell RNA - CACO-2 [nTPM]":"338.4","Cell RNA - CAPAN-2 [nTPM]":"159.6","Cell RNA - Daudi [nTPM]":"118.4","Cell RNA - EFO-21 [nTPM]":"186.8","Cell RNA - fHDF\/TERT166 [nTPM]":"85.9","Cell RNA - GAMG [nTPM]":"134.6","Cell RNA - HaCaT [nTPM]":"181.2","Cell RNA - HAP1 [nTPM]":"108.8","Cell RNA - HBEC3-KT [nTPM]":"128.4","Cell RNA - HBF TERT88 [nTPM]":"53.1","Cell RNA - HDLM-2 [nTPM]":"139.4","Cell RNA - HEK 293 [nTPM]":"264.9","Cell RNA - HEL [nTPM]":"107.2","Cell RNA - HeLa [nTPM]":"217.1","Cell RNA - Hep G2 [nTPM]":"186.3","Cell RNA - HHSteC [nTPM]":"171.8","Cell RNA - HL-60 [nTPM]":"99.1","Cell RNA - HMC-1 [nTPM]":"112.1","Cell RNA - HSkMC [nTPM]":"80.5","Cell RNA - hTCEpi [nTPM]":"126.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"111.1","Cell RNA - hTERT-HME1 [nTPM]":"124.8","Cell RNA - hTERT-RPE1 [nTPM]":"82.0","Cell RNA - HUVEC TERT2 [nTPM]":"106.2","Cell RNA - JURKAT [nTPM]":"159.9","Cell RNA - K-562 [nTPM]":"110.3","Cell RNA - Karpas-707 [nTPM]":"121.1","Cell RNA - LHCN-M2 [nTPM]":"99.2","Cell RNA - MCF7 [nTPM]":"358.6","Cell RNA - MOLT-4 [nTPM]":"219.2","Cell RNA - NB-4 [nTPM]":"216.9","Cell RNA - NTERA-2 [nTPM]":"125.2","Cell RNA - OE19 [nTPM]":"377.7","Cell RNA - PC-3 [nTPM]":"308.0","Cell RNA - REH [nTPM]":"154.4","Cell RNA - RH-30 [nTPM]":"95.9","Cell RNA - RPMI-8226 [nTPM]":"384.9","Cell RNA - RPTEC TERT1 [nTPM]":"192.8","Cell RNA - RT4 [nTPM]":"123.3","Cell RNA - SCLC-21H [nTPM]":"125.5","Cell RNA - SH-SY5Y [nTPM]":"102.2","Cell RNA - SiHa [nTPM]":"75.7","Cell RNA - SK-BR-3 [nTPM]":"171.7","Cell RNA - SK-MEL-30 [nTPM]":"392.3","Cell RNA - SuSa [nTPM]":"66.5","Cell RNA - T-47d [nTPM]":"245.6","Cell RNA - THP-1 [nTPM]":"105.9","Cell RNA - TIME [nTPM]":"84.1","Cell RNA - U-138 MG [nTPM]":"155.6","Cell RNA - U-2 OS [nTPM]":"133.9","Cell RNA - U-2197 [nTPM]":"224.8","Cell RNA - U-251 MG [nTPM]":"148.8","Cell RNA - U-266\/70 [nTPM]":"165.2","Cell RNA - U-266\/84 [nTPM]":"188.5","Cell RNA - U-698 [nTPM]":"99.7","Cell RNA - U-87 MG [nTPM]":"252.3","Cell RNA - U-937 [nTPM]":"121.8","Cell RNA - WM-115 [nTPM]":"111.2","Blood RNA - basophil [nTPM]":"84.7","Blood RNA - classical monocyte [nTPM]":"220.1","Blood RNA - eosinophil [nTPM]":"124.0","Blood RNA - gdT-cell [nTPM]":"182.4","Blood RNA - intermediate monocyte [nTPM]":"232.0","Blood RNA - MAIT T-cell [nTPM]":"170.1","Blood RNA - memory B-cell [nTPM]":"183.3","Blood RNA - memory CD4 T-cell [nTPM]":"154.6","Blood RNA - memory CD8 T-cell [nTPM]":"165.5","Blood RNA - myeloid DC [nTPM]":"309.4","Blood RNA - naive B-cell [nTPM]":"156.3","Blood RNA - naive CD4 T-cell [nTPM]":"146.2","Blood RNA - naive CD8 T-cell [nTPM]":"164.2","Blood RNA - neutrophil [nTPM]":"20.7","Blood RNA - NK-cell [nTPM]":"309.6","Blood RNA - non-classical monocyte [nTPM]":"131.7","Blood RNA - plasmacytoid DC [nTPM]":"324.3","Blood RNA - T-reg [nTPM]":"202.2","Blood RNA - total PBMC [nTPM]":"232.4","Brain RNA - amygdala [nTPM]":"141.2","Brain RNA - basal ganglia [nTPM]":"153.2","Brain RNA - cerebellum [nTPM]":"157.2","Brain RNA - cerebral cortex [nTPM]":"180.4","Brain RNA - hippocampal formation [nTPM]":"144.2","Brain RNA - hypothalamus [nTPM]":"152.0","Brain RNA - medulla oblongata [nTPM]":"149.6","Brain RNA - midbrain [nTPM]":"144.9","Brain RNA - pons [nTPM]":"145.8","Brain RNA - spinal cord [nTPM]":"142.2","Brain RNA - thalamus [nTPM]":"154.0","Brain RNA - white matter [nTPM]":"150.2","Single Cell Type RNA - Adipocytes [nTPM]":"88.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"89.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"90.1","Single Cell Type RNA - Astrocytes [nTPM]":"18.6","Single Cell Type RNA - B-cells [nTPM]":"92.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"85.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"95.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"284.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"104.7","Single Cell Type RNA - Bipolar cells [nTPM]":"83.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"147.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"156.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"301.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"143.0","Single Cell Type RNA - Club cells [nTPM]":"164.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"213.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"54.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"279.6","Single Cell Type RNA - dendritic cells [nTPM]":"97.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"301.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"833.5","Single Cell Type RNA - Ductal cells [nTPM]":"200.8","Single Cell Type RNA - Early spermatids [nTPM]":"225.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"101.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"74.8","Single Cell Type RNA - Endothelial cells [nTPM]":"85.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"205.0","Single Cell Type RNA - Erythroid cells [nTPM]":"149.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"199.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"165.9","Single Cell Type RNA - Fibroblasts [nTPM]":"109.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"147.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"79.7","Single Cell Type RNA - granulocytes [nTPM]":"95.8","Single Cell Type RNA - Granulosa cells [nTPM]":"156.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"73.5","Single Cell Type RNA - Hepatocytes [nTPM]":"231.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"276.6","Single Cell Type RNA - Horizontal cells [nTPM]":"50.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"19.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"277.2","Single Cell Type RNA - Ionocytes [nTPM]":"240.1","Single Cell Type RNA - Kupffer cells [nTPM]":"124.1","Single Cell Type RNA - Langerhans cells [nTPM]":"108.0","Single Cell Type RNA - Late spermatids [nTPM]":"797.2","Single Cell Type RNA - Leydig cells [nTPM]":"100.6","Single Cell Type RNA - Macrophages [nTPM]":"128.7","Single Cell Type RNA - Melanocytes [nTPM]":"163.7","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"187.4","Single Cell Type RNA - Muller glia cells [nTPM]":"143.6","Single Cell Type RNA - NK-cells [nTPM]":"128.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"173.7","Single Cell Type RNA - Paneth cells [nTPM]":"194.9","Single Cell Type RNA - Peritubular cells [nTPM]":"108.0","Single Cell Type RNA - Plasma cells [nTPM]":"157.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"118.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"337.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"927.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"120.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"118.7","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"81.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"208.6","Single Cell Type RNA - Spermatocytes [nTPM]":"105.9","Single Cell Type RNA - Spermatogonia [nTPM]":"72.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"209.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"116.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"172.4","Single Cell Type RNA - T-cells [nTPM]":"102.7","Single Cell Type RNA - Theca cells [nTPM]":"278.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"318.2","Single Cell Type RNA - Urothelial cells [nTPM]":"139.1"},{"Gene":"NDUFV1","Gene synonym":["CI-51K"],"Ensembl":"ENSG00000167792","Gene description":"NADH:ubiquinone oxidoreductase core subunit V1","Uniprot":["P49821"],"Chromosome":"11","Position":"67605653-67612554","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Oxidoreductase","Translocase"],"Disease involvement":["Disease variant","Leigh syndrome","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"526.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"482.4","Proximal tubular cells":"499.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045211","HPA075051"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"37000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA045211":"AB_10962830","HPA075051":"AB_2686732"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.49e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Tissue RNA - adipose tissue [nTPM]":"95.0","Tissue RNA - adrenal gland [nTPM]":"126.5","Tissue RNA - amygdala [nTPM]":"87.6","Tissue RNA - appendix [nTPM]":"52.5","Tissue RNA - basal ganglia [nTPM]":"93.7","Tissue RNA - bone marrow [nTPM]":"72.5","Tissue RNA - breast [nTPM]":"90.9","Tissue RNA - cerebellum [nTPM]":"105.6","Tissue RNA - cerebral cortex [nTPM]":"107.1","Tissue RNA - cervix [nTPM]":"93.9","Tissue RNA - choroid plexus [nTPM]":"104.8","Tissue RNA - colon [nTPM]":"142.3","Tissue RNA - duodenum [nTPM]":"124.5","Tissue RNA - endometrium 1 [nTPM]":"85.2","Tissue RNA - epididymis [nTPM]":"33.8","Tissue RNA - esophagus [nTPM]":"114.0","Tissue RNA - fallopian tube [nTPM]":"84.6","Tissue RNA - gallbladder [nTPM]":"47.1","Tissue RNA - heart muscle [nTPM]":"400.2","Tissue RNA - hippocampal formation [nTPM]":"91.6","Tissue RNA - hypothalamus [nTPM]":"97.0","Tissue RNA - kidney [nTPM]":"188.4","Tissue RNA - liver [nTPM]":"187.0","Tissue RNA - lung [nTPM]":"77.1","Tissue RNA - lymph node [nTPM]":"66.7","Tissue RNA - medulla oblongata [nTPM]":"103.3","Tissue RNA - midbrain [nTPM]":"91.5","Tissue RNA - ovary [nTPM]":"101.9","Tissue RNA - pancreas [nTPM]":"117.2","Tissue RNA - parathyroid gland [nTPM]":"169.8","Tissue RNA - pituitary gland [nTPM]":"84.5","Tissue RNA - placenta [nTPM]":"46.7","Tissue RNA - pons [nTPM]":"110.4","Tissue RNA - prostate [nTPM]":"77.4","Tissue RNA - rectum [nTPM]":"73.7","Tissue RNA - retina [nTPM]":"81.6","Tissue RNA - salivary gland [nTPM]":"90.2","Tissue RNA - seminal vesicle [nTPM]":"73.2","Tissue RNA - skeletal muscle [nTPM]":"526.2","Tissue RNA - skin 1 [nTPM]":"117.7","Tissue RNA - small intestine [nTPM]":"96.6","Tissue RNA - smooth muscle [nTPM]":"51.1","Tissue RNA - spinal cord [nTPM]":"86.9","Tissue RNA - spleen [nTPM]":"98.8","Tissue RNA - stomach 1 [nTPM]":"132.0","Tissue RNA - testis [nTPM]":"76.0","Tissue RNA - thalamus [nTPM]":"104.9","Tissue RNA - thymus [nTPM]":"51.6","Tissue RNA - thyroid gland [nTPM]":"107.6","Tissue RNA - tongue [nTPM]":"440.5","Tissue RNA - tonsil [nTPM]":"62.8","Tissue RNA - urinary bladder [nTPM]":"88.1","Tissue RNA - vagina [nTPM]":"88.6","Tissue RNA - white matter [nTPM]":"99.9","Cell RNA - A-431 [nTPM]":"132.9","Cell RNA - A549 [nTPM]":"133.6","Cell RNA - AF22 [nTPM]":"68.8","Cell RNA - AN3-CA [nTPM]":"141.3","Cell RNA - ASC diff [nTPM]":"85.6","Cell RNA - ASC TERT1 [nTPM]":"83.4","Cell RNA - BEWO [nTPM]":"130.6","Cell RNA - BJ [nTPM]":"84.1","Cell RNA - BJ hTERT+ [nTPM]":"76.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"122.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"82.6","Cell RNA - CACO-2 [nTPM]":"256.8","Cell RNA - CAPAN-2 [nTPM]":"155.3","Cell RNA - Daudi [nTPM]":"241.9","Cell RNA - EFO-21 [nTPM]":"167.3","Cell RNA - fHDF\/TERT166 [nTPM]":"69.2","Cell RNA - GAMG [nTPM]":"99.7","Cell RNA - HaCaT [nTPM]":"176.8","Cell RNA - HAP1 [nTPM]":"146.1","Cell RNA - HBEC3-KT [nTPM]":"126.4","Cell RNA - HBF TERT88 [nTPM]":"38.4","Cell RNA - HDLM-2 [nTPM]":"125.2","Cell RNA - HEK 293 [nTPM]":"114.9","Cell RNA - HEL [nTPM]":"100.0","Cell RNA - HeLa [nTPM]":"189.1","Cell RNA - Hep G2 [nTPM]":"127.9","Cell RNA - HHSteC [nTPM]":"119.0","Cell RNA - HL-60 [nTPM]":"136.9","Cell RNA - HMC-1 [nTPM]":"106.9","Cell RNA - HSkMC [nTPM]":"126.7","Cell RNA - hTCEpi [nTPM]":"119.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"100.4","Cell RNA - hTERT-HME1 [nTPM]":"88.0","Cell RNA - hTERT-RPE1 [nTPM]":"76.9","Cell RNA - HUVEC TERT2 [nTPM]":"109.3","Cell RNA - JURKAT [nTPM]":"173.9","Cell RNA - K-562 [nTPM]":"180.9","Cell RNA - Karpas-707 [nTPM]":"192.6","Cell RNA - LHCN-M2 [nTPM]":"75.8","Cell RNA - MCF7 [nTPM]":"190.2","Cell RNA - MOLT-4 [nTPM]":"163.1","Cell RNA - NB-4 [nTPM]":"268.0","Cell RNA - NTERA-2 [nTPM]":"68.5","Cell RNA - OE19 [nTPM]":"295.3","Cell RNA - PC-3 [nTPM]":"168.8","Cell RNA - REH [nTPM]":"184.5","Cell RNA - RH-30 [nTPM]":"135.8","Cell RNA - RPMI-8226 [nTPM]":"399.1","Cell RNA - RPTEC TERT1 [nTPM]":"99.3","Cell RNA - RT4 [nTPM]":"95.3","Cell RNA - SCLC-21H [nTPM]":"109.9","Cell RNA - SH-SY5Y [nTPM]":"104.6","Cell RNA - SiHa [nTPM]":"104.3","Cell RNA - SK-BR-3 [nTPM]":"347.4","Cell RNA - SK-MEL-30 [nTPM]":"275.3","Cell RNA - SuSa [nTPM]":"46.0","Cell RNA - T-47d [nTPM]":"177.4","Cell RNA - THP-1 [nTPM]":"138.0","Cell RNA - TIME [nTPM]":"90.7","Cell RNA - U-138 MG [nTPM]":"118.9","Cell RNA - U-2 OS [nTPM]":"88.8","Cell RNA - U-2197 [nTPM]":"172.3","Cell RNA - U-251 MG [nTPM]":"87.5","Cell RNA - U-266\/70 [nTPM]":"187.7","Cell RNA - U-266\/84 [nTPM]":"116.8","Cell RNA - U-698 [nTPM]":"122.6","Cell RNA - U-87 MG [nTPM]":"138.0","Cell RNA - U-937 [nTPM]":"144.6","Cell RNA - WM-115 [nTPM]":"117.7","Blood RNA - basophil [nTPM]":"39.0","Blood RNA - classical monocyte [nTPM]":"72.8","Blood RNA - eosinophil [nTPM]":"38.1","Blood RNA - gdT-cell [nTPM]":"65.1","Blood RNA - intermediate monocyte [nTPM]":"83.4","Blood RNA - MAIT T-cell [nTPM]":"71.6","Blood RNA - memory B-cell [nTPM]":"59.8","Blood RNA - memory CD4 T-cell [nTPM]":"55.0","Blood RNA - memory CD8 T-cell [nTPM]":"63.2","Blood RNA - myeloid DC [nTPM]":"110.7","Blood RNA - naive B-cell [nTPM]":"60.1","Blood RNA - naive CD4 T-cell [nTPM]":"50.2","Blood RNA - naive CD8 T-cell [nTPM]":"63.7","Blood RNA - neutrophil [nTPM]":"13.1","Blood RNA - NK-cell [nTPM]":"104.0","Blood RNA - non-classical monocyte [nTPM]":"51.2","Blood RNA - plasmacytoid DC [nTPM]":"73.0","Blood RNA - T-reg [nTPM]":"78.1","Blood RNA - total PBMC [nTPM]":"77.0","Brain RNA - amygdala [nTPM]":"87.6","Brain RNA - basal ganglia [nTPM]":"93.7","Brain RNA - cerebellum [nTPM]":"105.6","Brain RNA - cerebral cortex [nTPM]":"107.1","Brain RNA - hippocampal formation [nTPM]":"91.6","Brain RNA - hypothalamus [nTPM]":"97.0","Brain RNA - medulla oblongata [nTPM]":"103.3","Brain RNA - midbrain [nTPM]":"91.5","Brain RNA - pons [nTPM]":"110.4","Brain RNA - spinal cord [nTPM]":"86.9","Brain RNA - thalamus [nTPM]":"104.9","Brain RNA - white matter [nTPM]":"99.9","Single Cell Type RNA - Adipocytes [nTPM]":"54.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"75.0","Single Cell Type RNA - Astrocytes [nTPM]":"33.3","Single Cell Type RNA - B-cells [nTPM]":"76.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"80.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"95.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"187.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"77.4","Single Cell Type RNA - Bipolar cells [nTPM]":"68.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"82.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"94.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"482.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"61.5","Single Cell Type RNA - Club cells [nTPM]":"120.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"86.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"50.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"203.5","Single Cell Type RNA - dendritic cells [nTPM]":"72.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"235.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"397.2","Single Cell Type RNA - Ductal cells [nTPM]":"114.9","Single Cell Type RNA - Early spermatids [nTPM]":"74.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"43.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"47.5","Single Cell Type RNA - Endothelial cells [nTPM]":"56.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"98.5","Single Cell Type RNA - Erythroid cells [nTPM]":"85.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"32.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"112.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"158.8","Single Cell Type RNA - Fibroblasts [nTPM]":"82.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"137.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"55.2","Single Cell Type RNA - granulocytes [nTPM]":"61.4","Single Cell Type RNA - Granulosa cells [nTPM]":"99.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"56.4","Single Cell Type RNA - Hepatocytes [nTPM]":"136.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"136.5","Single Cell Type RNA - Horizontal cells [nTPM]":"63.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"36.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"155.9","Single Cell Type RNA - Ionocytes [nTPM]":"152.5","Single Cell Type RNA - Kupffer cells [nTPM]":"68.8","Single Cell Type RNA - Langerhans cells [nTPM]":"81.4","Single Cell Type RNA - Late spermatids [nTPM]":"222.7","Single Cell Type RNA - Leydig cells [nTPM]":"65.6","Single Cell Type RNA - Macrophages [nTPM]":"68.4","Single Cell Type RNA - Melanocytes [nTPM]":"113.8","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"81.0","Single Cell Type RNA - Muller glia cells [nTPM]":"89.3","Single Cell Type RNA - NK-cells [nTPM]":"60.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"34.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"70.1","Single Cell Type RNA - Paneth cells [nTPM]":"122.8","Single Cell Type RNA - Peritubular cells [nTPM]":"59.0","Single Cell Type RNA - Plasma cells [nTPM]":"146.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"55.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"199.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"499.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"80.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"78.5","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"90.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"136.9","Single Cell Type RNA - Spermatocytes [nTPM]":"100.7","Single Cell Type RNA - Spermatogonia [nTPM]":"83.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"127.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"80.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"189.1","Single Cell Type RNA - T-cells [nTPM]":"79.3","Single Cell Type RNA - Theca cells [nTPM]":"145.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"274.8","Single Cell Type RNA - Urothelial cells [nTPM]":"111.7"},{"Gene":"NDUFV2","Gene synonym":["CI-24k"],"Ensembl":"ENSG00000178127","Gene description":"NADH:ubiquinone oxidoreductase core subunit V2","Uniprot":["P19404"],"Chromosome":"18","Position":"9102630-9134345","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Oxidoreductase","Translocase"],"Disease involvement":["Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"606.9"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003404","HPA077896"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7600","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA003404":"AB_1079466","HPA077896":"AB_2686866"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-3"},"Tissue RNA - adipose tissue [nTPM]":"97.4","Tissue RNA - adrenal gland [nTPM]":"171.6","Tissue RNA - amygdala [nTPM]":"94.3","Tissue RNA - appendix [nTPM]":"69.2","Tissue RNA - basal ganglia [nTPM]":"97.4","Tissue RNA - bone marrow [nTPM]":"149.8","Tissue RNA - breast [nTPM]":"101.7","Tissue RNA - cerebellum [nTPM]":"106.8","Tissue RNA - cerebral cortex [nTPM]":"139.7","Tissue RNA - cervix [nTPM]":"63.9","Tissue RNA - choroid plexus [nTPM]":"106.0","Tissue RNA - colon [nTPM]":"124.2","Tissue RNA - duodenum [nTPM]":"102.3","Tissue RNA - endometrium 1 [nTPM]":"69.7","Tissue RNA - epididymis [nTPM]":"91.1","Tissue RNA - esophagus [nTPM]":"142.6","Tissue RNA - fallopian tube [nTPM]":"64.0","Tissue RNA - gallbladder [nTPM]":"68.7","Tissue RNA - heart muscle [nTPM]":"419.3","Tissue RNA - hippocampal formation [nTPM]":"96.7","Tissue RNA - hypothalamus [nTPM]":"106.0","Tissue RNA - kidney [nTPM]":"180.7","Tissue RNA - liver [nTPM]":"404.2","Tissue RNA - lung [nTPM]":"88.6","Tissue RNA - lymph node [nTPM]":"105.0","Tissue RNA - medulla oblongata [nTPM]":"105.9","Tissue RNA - midbrain [nTPM]":"104.4","Tissue RNA - ovary [nTPM]":"52.4","Tissue RNA - pancreas [nTPM]":"111.6","Tissue RNA - parathyroid gland [nTPM]":"136.7","Tissue RNA - pituitary gland [nTPM]":"72.1","Tissue RNA - placenta [nTPM]":"73.7","Tissue RNA - pons [nTPM]":"105.9","Tissue RNA - prostate [nTPM]":"88.5","Tissue RNA - rectum [nTPM]":"119.8","Tissue RNA - retina [nTPM]":"129.9","Tissue RNA - salivary gland [nTPM]":"97.4","Tissue RNA - seminal vesicle [nTPM]":"72.4","Tissue RNA - skeletal muscle [nTPM]":"606.9","Tissue RNA - skin 1 [nTPM]":"94.7","Tissue RNA - small intestine [nTPM]":"100.5","Tissue RNA - smooth muscle [nTPM]":"80.6","Tissue RNA - spinal cord [nTPM]":"103.7","Tissue RNA - spleen [nTPM]":"86.4","Tissue RNA - stomach 1 [nTPM]":"133.8","Tissue RNA - testis [nTPM]":"79.6","Tissue RNA - thalamus [nTPM]":"102.7","Tissue RNA - thymus [nTPM]":"90.2","Tissue RNA - thyroid gland [nTPM]":"72.7","Tissue RNA - tongue [nTPM]":"538.3","Tissue RNA - tonsil [nTPM]":"105.1","Tissue RNA - urinary bladder [nTPM]":"122.1","Tissue RNA - vagina [nTPM]":"76.5","Tissue RNA - white matter [nTPM]":"104.6","Cell RNA - A-431 [nTPM]":"136.5","Cell RNA - A549 [nTPM]":"139.8","Cell RNA - AF22 [nTPM]":"159.1","Cell RNA - AN3-CA [nTPM]":"148.4","Cell RNA - ASC diff [nTPM]":"116.6","Cell RNA - ASC TERT1 [nTPM]":"164.0","Cell RNA - BEWO [nTPM]":"133.4","Cell RNA - BJ [nTPM]":"165.4","Cell RNA - BJ hTERT+ [nTPM]":"266.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"217.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"205.5","Cell RNA - CACO-2 [nTPM]":"265.1","Cell RNA - CAPAN-2 [nTPM]":"109.4","Cell RNA - Daudi [nTPM]":"209.4","Cell RNA - EFO-21 [nTPM]":"149.5","Cell RNA - fHDF\/TERT166 [nTPM]":"158.6","Cell RNA - GAMG [nTPM]":"200.3","Cell RNA - HaCaT [nTPM]":"66.9","Cell RNA - HAP1 [nTPM]":"157.5","Cell RNA - HBEC3-KT [nTPM]":"175.5","Cell RNA - HBF TERT88 [nTPM]":"208.8","Cell RNA - HDLM-2 [nTPM]":"104.6","Cell RNA - HEK 293 [nTPM]":"136.6","Cell RNA - HEL [nTPM]":"133.0","Cell RNA - HeLa [nTPM]":"135.3","Cell RNA - Hep G2 [nTPM]":"364.8","Cell RNA - HHSteC [nTPM]":"133.6","Cell RNA - HL-60 [nTPM]":"373.8","Cell RNA - HMC-1 [nTPM]":"159.2","Cell RNA - HSkMC [nTPM]":"139.2","Cell RNA - hTCEpi [nTPM]":"144.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"134.9","Cell RNA - hTERT-HME1 [nTPM]":"146.2","Cell RNA - hTERT-RPE1 [nTPM]":"156.8","Cell RNA - HUVEC TERT2 [nTPM]":"239.3","Cell RNA - JURKAT [nTPM]":"184.3","Cell RNA - K-562 [nTPM]":"216.5","Cell RNA - Karpas-707 [nTPM]":"644.0","Cell RNA - LHCN-M2 [nTPM]":"204.6","Cell RNA - MCF7 [nTPM]":"171.6","Cell RNA - MOLT-4 [nTPM]":"263.5","Cell RNA - NB-4 [nTPM]":"328.9","Cell RNA - NTERA-2 [nTPM]":"131.4","Cell RNA - OE19 [nTPM]":"750.5","Cell RNA - PC-3 [nTPM]":"172.3","Cell RNA - REH [nTPM]":"124.5","Cell RNA - RH-30 [nTPM]":"118.2","Cell RNA - RPMI-8226 [nTPM]":"794.2","Cell RNA - RPTEC TERT1 [nTPM]":"354.3","Cell RNA - RT4 [nTPM]":"218.7","Cell RNA - SCLC-21H [nTPM]":"167.0","Cell RNA - SH-SY5Y [nTPM]":"122.3","Cell RNA - SiHa [nTPM]":"164.6","Cell RNA - SK-BR-3 [nTPM]":"188.0","Cell RNA - SK-MEL-30 [nTPM]":"220.3","Cell RNA - SuSa [nTPM]":"113.6","Cell RNA - T-47d [nTPM]":"174.2","Cell RNA - THP-1 [nTPM]":"282.8","Cell RNA - TIME [nTPM]":"145.8","Cell RNA - U-138 MG [nTPM]":"273.4","Cell RNA - U-2 OS [nTPM]":"194.3","Cell RNA - U-2197 [nTPM]":"198.8","Cell RNA - U-251 MG [nTPM]":"223.0","Cell RNA - U-266\/70 [nTPM]":"180.4","Cell RNA - U-266\/84 [nTPM]":"292.3","Cell RNA - U-698 [nTPM]":"237.1","Cell RNA - U-87 MG [nTPM]":"195.4","Cell RNA - U-937 [nTPM]":"166.0","Cell RNA - WM-115 [nTPM]":"181.0","Blood RNA - basophil [nTPM]":"250.8","Blood RNA - classical monocyte [nTPM]":"161.8","Blood RNA - eosinophil [nTPM]":"194.2","Blood RNA - gdT-cell [nTPM]":"118.1","Blood RNA - intermediate monocyte [nTPM]":"196.1","Blood RNA - MAIT T-cell [nTPM]":"148.3","Blood RNA - memory B-cell [nTPM]":"237.6","Blood RNA - memory CD4 T-cell [nTPM]":"176.9","Blood RNA - memory CD8 T-cell [nTPM]":"140.5","Blood RNA - myeloid DC [nTPM]":"237.9","Blood RNA - naive B-cell [nTPM]":"201.1","Blood RNA - naive CD4 T-cell [nTPM]":"153.5","Blood RNA - naive CD8 T-cell [nTPM]":"142.7","Blood RNA - neutrophil [nTPM]":"76.0","Blood RNA - NK-cell [nTPM]":"124.2","Blood RNA - non-classical monocyte [nTPM]":"187.9","Blood RNA - plasmacytoid DC [nTPM]":"315.1","Blood RNA - T-reg [nTPM]":"231.9","Blood RNA - total PBMC [nTPM]":"231.8","Brain RNA - amygdala [nTPM]":"94.3","Brain RNA - basal ganglia [nTPM]":"97.4","Brain RNA - cerebellum [nTPM]":"106.8","Brain RNA - cerebral cortex [nTPM]":"139.7","Brain RNA - hippocampal formation [nTPM]":"96.7","Brain RNA - hypothalamus [nTPM]":"106.0","Brain RNA - medulla oblongata [nTPM]":"105.9","Brain RNA - midbrain [nTPM]":"104.4","Brain RNA - pons [nTPM]":"105.9","Brain RNA - spinal cord [nTPM]":"103.7","Brain RNA - thalamus [nTPM]":"102.7","Brain RNA - white matter [nTPM]":"104.6","Single Cell Type RNA - Adipocytes [nTPM]":"107.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"80.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"145.8","Single Cell Type RNA - Astrocytes [nTPM]":"17.6","Single Cell Type RNA - B-cells [nTPM]":"143.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"148.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"319.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"629.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"159.4","Single Cell Type RNA - Bipolar cells [nTPM]":"101.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"165.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"167.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"69.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"178.7","Single Cell Type RNA - Club cells [nTPM]":"339.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"150.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"87.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"344.1","Single Cell Type RNA - dendritic cells [nTPM]":"146.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"211.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"876.5","Single Cell Type RNA - Ductal cells [nTPM]":"415.2","Single Cell Type RNA - Early spermatids [nTPM]":"271.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"160.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"108.2","Single Cell Type RNA - Endothelial cells [nTPM]":"117.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"106.5","Single Cell Type RNA - Erythroid cells [nTPM]":"165.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"32.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"531.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"323.3","Single Cell Type RNA - Fibroblasts [nTPM]":"122.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"144.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"183.9","Single Cell Type RNA - granulocytes [nTPM]":"120.3","Single Cell Type RNA - Granulosa cells [nTPM]":"109.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"96.4","Single Cell Type RNA - Hepatocytes [nTPM]":"351.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"313.5","Single Cell Type RNA - Horizontal cells [nTPM]":"94.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"201.7","Single Cell Type RNA - Ionocytes [nTPM]":"480.1","Single Cell Type RNA - Kupffer cells [nTPM]":"115.7","Single Cell Type RNA - Langerhans cells [nTPM]":"267.1","Single Cell Type RNA - Late spermatids [nTPM]":"186.2","Single Cell Type RNA - Leydig cells [nTPM]":"122.1","Single Cell Type RNA - Macrophages [nTPM]":"170.2","Single Cell Type RNA - Melanocytes [nTPM]":"231.3","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"293.2","Single Cell Type RNA - Muller glia cells [nTPM]":"167.1","Single Cell Type RNA - NK-cells [nTPM]":"96.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"32.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"46.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"530.3","Single Cell Type RNA - Paneth cells [nTPM]":"201.2","Single Cell Type RNA - Peritubular cells [nTPM]":"102.0","Single Cell Type RNA - Plasma cells [nTPM]":"244.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"554.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"349.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"810.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"293.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"184.2","Single Cell Type RNA - Sertoli cells [nTPM]":"105.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"124.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"196.3","Single Cell Type RNA - Spermatocytes [nTPM]":"217.4","Single Cell Type RNA - Spermatogonia [nTPM]":"175.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"226.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"147.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"289.4","Single Cell Type RNA - T-cells [nTPM]":"165.7","Single Cell Type RNA - Theca cells [nTPM]":"266.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"227.3","Single Cell Type RNA - Urothelial cells [nTPM]":"469.0"},{"Gene":"NEDD4L","Gene synonym":["KIAA0439","NEDD4-2","RSP5"],"Ensembl":"ENSG00000049759","Gene description":"NEDD4 like E3 ubiquitin protein ligase","Uniprot":["Q96PU5"],"Chromosome":"18","Position":"58044226-58401540","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Differentiation","Host-virus interaction","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"253.2","Excitatory neurons":"280.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"29.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"T-reg":"5.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"T-cells":"5.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SK-MEL-30":"146.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024618"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA024618":"AB_1854362"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.24e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.55e-15"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.2","Tissue RNA - adrenal gland [nTPM]":"16.8","Tissue RNA - amygdala [nTPM]":"20.9","Tissue RNA - appendix [nTPM]":"6.7","Tissue RNA - basal ganglia [nTPM]":"34.4","Tissue RNA - bone marrow [nTPM]":"27.0","Tissue RNA - breast [nTPM]":"25.8","Tissue RNA - cerebellum [nTPM]":"25.1","Tissue RNA - cerebral cortex [nTPM]":"31.3","Tissue RNA - cervix [nTPM]":"7.6","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"38.8","Tissue RNA - duodenum [nTPM]":"18.7","Tissue RNA - endometrium 1 [nTPM]":"5.3","Tissue RNA - epididymis [nTPM]":"10.0","Tissue RNA - esophagus [nTPM]":"12.0","Tissue RNA - fallopian tube [nTPM]":"9.1","Tissue RNA - gallbladder [nTPM]":"9.5","Tissue RNA - heart muscle [nTPM]":"26.9","Tissue RNA - hippocampal formation [nTPM]":"32.3","Tissue RNA - hypothalamus [nTPM]":"16.2","Tissue RNA - kidney [nTPM]":"53.4","Tissue RNA - liver [nTPM]":"36.5","Tissue RNA - lung [nTPM]":"47.9","Tissue RNA - lymph node [nTPM]":"4.1","Tissue RNA - medulla oblongata [nTPM]":"10.9","Tissue RNA - midbrain [nTPM]":"18.4","Tissue RNA - ovary [nTPM]":"6.4","Tissue RNA - pancreas [nTPM]":"60.5","Tissue RNA - parathyroid gland [nTPM]":"13.6","Tissue RNA - pituitary gland [nTPM]":"28.4","Tissue RNA - placenta [nTPM]":"12.0","Tissue RNA - pons [nTPM]":"10.4","Tissue RNA - prostate [nTPM]":"64.2","Tissue RNA - rectum [nTPM]":"42.8","Tissue RNA - retina [nTPM]":"20.5","Tissue RNA - salivary gland [nTPM]":"27.5","Tissue RNA - seminal vesicle [nTPM]":"20.4","Tissue RNA - skeletal muscle [nTPM]":"34.0","Tissue RNA - skin 1 [nTPM]":"11.2","Tissue RNA - small intestine [nTPM]":"33.8","Tissue RNA - smooth muscle [nTPM]":"6.2","Tissue RNA - spinal cord [nTPM]":"8.6","Tissue RNA - spleen [nTPM]":"7.9","Tissue RNA - stomach 1 [nTPM]":"51.5","Tissue RNA - testis [nTPM]":"7.8","Tissue RNA - thalamus [nTPM]":"16.7","Tissue RNA - thymus [nTPM]":"4.5","Tissue RNA - thyroid gland [nTPM]":"17.4","Tissue RNA - tongue [nTPM]":"13.1","Tissue RNA - tonsil [nTPM]":"7.9","Tissue RNA - urinary bladder [nTPM]":"19.4","Tissue RNA - vagina [nTPM]":"5.9","Tissue RNA - white matter [nTPM]":"16.3","Cell RNA - A-431 [nTPM]":"70.7","Cell RNA - A549 [nTPM]":"24.5","Cell RNA - AF22 [nTPM]":"14.6","Cell RNA - AN3-CA [nTPM]":"20.9","Cell RNA - ASC diff [nTPM]":"5.1","Cell RNA - ASC TERT1 [nTPM]":"2.1","Cell RNA - BEWO [nTPM]":"49.8","Cell RNA - BJ [nTPM]":"19.2","Cell RNA - BJ hTERT+ [nTPM]":"88.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"48.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"74.6","Cell RNA - CACO-2 [nTPM]":"28.6","Cell RNA - CAPAN-2 [nTPM]":"37.1","Cell RNA - Daudi [nTPM]":"15.1","Cell RNA - EFO-21 [nTPM]":"57.7","Cell RNA - fHDF\/TERT166 [nTPM]":"7.4","Cell RNA - GAMG [nTPM]":"51.3","Cell RNA - HaCaT [nTPM]":"50.3","Cell RNA - HAP1 [nTPM]":"19.5","Cell RNA - HBEC3-KT [nTPM]":"86.1","Cell RNA - HBF TERT88 [nTPM]":"100.8","Cell RNA - HDLM-2 [nTPM]":"34.9","Cell RNA - HEK 293 [nTPM]":"15.5","Cell RNA - HEL [nTPM]":"10.6","Cell RNA - HeLa [nTPM]":"14.3","Cell RNA - Hep G2 [nTPM]":"111.3","Cell RNA - HHSteC [nTPM]":"2.4","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"6.0","Cell RNA - HSkMC [nTPM]":"13.0","Cell RNA - hTCEpi [nTPM]":"54.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"66.4","Cell RNA - hTERT-HME1 [nTPM]":"78.8","Cell RNA - hTERT-RPE1 [nTPM]":"39.1","Cell RNA - HUVEC TERT2 [nTPM]":"4.0","Cell RNA - JURKAT [nTPM]":"13.2","Cell RNA - K-562 [nTPM]":"18.7","Cell RNA - Karpas-707 [nTPM]":"6.3","Cell RNA - LHCN-M2 [nTPM]":"20.0","Cell RNA - MCF7 [nTPM]":"16.2","Cell RNA - MOLT-4 [nTPM]":"1.0","Cell RNA - NB-4 [nTPM]":"1.0","Cell RNA - NTERA-2 [nTPM]":"12.2","Cell RNA - OE19 [nTPM]":"26.7","Cell RNA - PC-3 [nTPM]":"33.3","Cell RNA - REH [nTPM]":"14.3","Cell RNA - RH-30 [nTPM]":"20.1","Cell RNA - RPMI-8226 [nTPM]":"17.6","Cell RNA - RPTEC TERT1 [nTPM]":"47.0","Cell RNA - RT4 [nTPM]":"88.7","Cell RNA - SCLC-21H [nTPM]":"17.5","Cell RNA - SH-SY5Y [nTPM]":"5.0","Cell RNA - SiHa [nTPM]":"16.1","Cell RNA - SK-BR-3 [nTPM]":"5.1","Cell RNA - SK-MEL-30 [nTPM]":"146.1","Cell RNA - SuSa [nTPM]":"28.3","Cell RNA - T-47d [nTPM]":"29.4","Cell RNA - THP-1 [nTPM]":"5.6","Cell RNA - TIME [nTPM]":"28.8","Cell RNA - U-138 MG [nTPM]":"131.5","Cell RNA - U-2 OS [nTPM]":"38.5","Cell RNA - U-2197 [nTPM]":"7.5","Cell RNA - U-251 MG [nTPM]":"83.4","Cell RNA - U-266\/70 [nTPM]":"8.3","Cell RNA - U-266\/84 [nTPM]":"15.3","Cell RNA - U-698 [nTPM]":"9.5","Cell RNA - U-87 MG [nTPM]":"27.6","Cell RNA - U-937 [nTPM]":"10.8","Cell RNA - WM-115 [nTPM]":"10.8","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"1.2","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"5.1","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"20.9","Brain RNA - basal ganglia [nTPM]":"34.4","Brain RNA - cerebellum [nTPM]":"25.1","Brain RNA - cerebral cortex [nTPM]":"31.3","Brain RNA - hippocampal formation [nTPM]":"32.3","Brain RNA - hypothalamus [nTPM]":"16.2","Brain RNA - medulla oblongata [nTPM]":"10.9","Brain RNA - midbrain [nTPM]":"18.4","Brain RNA - pons [nTPM]":"10.4","Brain RNA - spinal cord [nTPM]":"8.6","Brain RNA - thalamus [nTPM]":"16.7","Brain RNA - white matter [nTPM]":"16.3","Single Cell Type RNA - Adipocytes [nTPM]":"6.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"253.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"144.8","Single Cell Type RNA - Astrocytes [nTPM]":"110.4","Single Cell Type RNA - B-cells [nTPM]":"5.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"112.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"161.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"34.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"86.6","Single Cell Type RNA - Bipolar cells [nTPM]":"18.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"99.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"65.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"47.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"64.3","Single Cell Type RNA - Club cells [nTPM]":"112.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"62.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"173.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.0","Single Cell Type RNA - dendritic cells [nTPM]":"3.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"144.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"49.0","Single Cell Type RNA - Ductal cells [nTPM]":"35.7","Single Cell Type RNA - Early spermatids [nTPM]":"22.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"64.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.3","Single Cell Type RNA - Endothelial cells [nTPM]":"14.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"45.2","Single Cell Type RNA - Erythroid cells [nTPM]":"57.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"280.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"49.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.7","Single Cell Type RNA - Fibroblasts [nTPM]":"9.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"114.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"75.0","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"4.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.5","Single Cell Type RNA - Hepatocytes [nTPM]":"41.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.3","Single Cell Type RNA - Horizontal cells [nTPM]":"62.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"173.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"201.5","Single Cell Type RNA - Ionocytes [nTPM]":"101.7","Single Cell Type RNA - Kupffer cells [nTPM]":"8.4","Single Cell Type RNA - Langerhans cells [nTPM]":"8.2","Single Cell Type RNA - Late spermatids [nTPM]":"6.6","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"13.3","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"88.1","Single Cell Type RNA - monocytes [nTPM]":"7.3","Single Cell Type RNA - Muller glia cells [nTPM]":"45.2","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"105.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"49.9","Single Cell Type RNA - Paneth cells [nTPM]":"145.3","Single Cell Type RNA - Peritubular cells [nTPM]":"17.7","Single Cell Type RNA - Plasma cells [nTPM]":"12.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"126.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"127.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"91.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"72.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"34.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.0","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"12.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"62.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"53.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"80.0","Single Cell Type RNA - T-cells [nTPM]":"6.6","Single Cell Type RNA - Theca cells [nTPM]":"8.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"72.9","Single Cell Type RNA - Urothelial cells [nTPM]":"155.5"},{"Gene":"NEK1","Gene synonym":["KIAA1901","NY-REN-55"],"Ensembl":"ENSG00000137601","Gene description":"NIMA related kinase 1","Uniprot":["Q96PY6"],"Chromosome":"4","Position":"169392809-169612627","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Cilium biogenesis\/degradation","Mitosis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Amyotrophic lateral sclerosis","Ciliopathy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"162.6","Excitatory neurons":"126.3","Inhibitory neurons":"170.5","Oligodendrocytes":"196.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020873","HPA040413"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm","Centriolar satellite"],"Antibody RRID":{"HPA020873":"AB_10671583","HPA040413":"AB_10671169"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.42e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.0","Tissue RNA - adrenal gland [nTPM]":"6.1","Tissue RNA - amygdala [nTPM]":"5.1","Tissue RNA - appendix [nTPM]":"4.9","Tissue RNA - basal ganglia [nTPM]":"6.8","Tissue RNA - bone marrow [nTPM]":"4.2","Tissue RNA - breast [nTPM]":"5.2","Tissue RNA - cerebellum [nTPM]":"7.1","Tissue RNA - cerebral cortex [nTPM]":"5.3","Tissue RNA - cervix [nTPM]":"7.6","Tissue RNA - choroid plexus [nTPM]":"2.7","Tissue RNA - colon [nTPM]":"4.0","Tissue RNA - duodenum [nTPM]":"3.2","Tissue RNA - endometrium 1 [nTPM]":"7.3","Tissue RNA - epididymis [nTPM]":"2.8","Tissue RNA - esophagus [nTPM]":"4.6","Tissue RNA - fallopian tube [nTPM]":"9.3","Tissue RNA - gallbladder [nTPM]":"6.1","Tissue RNA - heart muscle [nTPM]":"6.9","Tissue RNA - hippocampal formation [nTPM]":"3.5","Tissue RNA - hypothalamus [nTPM]":"8.8","Tissue RNA - kidney [nTPM]":"5.9","Tissue RNA - liver [nTPM]":"4.2","Tissue RNA - lung [nTPM]":"4.6","Tissue RNA - lymph node [nTPM]":"5.3","Tissue RNA - medulla oblongata [nTPM]":"7.5","Tissue RNA - midbrain [nTPM]":"7.7","Tissue RNA - ovary [nTPM]":"9.4","Tissue RNA - pancreas [nTPM]":"4.0","Tissue RNA - parathyroid gland [nTPM]":"6.5","Tissue RNA - pituitary gland [nTPM]":"2.9","Tissue RNA - placenta [nTPM]":"4.3","Tissue RNA - pons [nTPM]":"7.6","Tissue RNA - prostate [nTPM]":"6.7","Tissue RNA - rectum [nTPM]":"4.4","Tissue RNA - retina [nTPM]":"8.7","Tissue RNA - salivary gland [nTPM]":"4.2","Tissue RNA - seminal vesicle [nTPM]":"6.0","Tissue RNA - skeletal muscle [nTPM]":"3.3","Tissue RNA - skin 1 [nTPM]":"2.3","Tissue RNA - small intestine [nTPM]":"3.5","Tissue RNA - smooth muscle [nTPM]":"6.6","Tissue RNA - spinal cord [nTPM]":"7.6","Tissue RNA - spleen [nTPM]":"5.1","Tissue RNA - stomach 1 [nTPM]":"4.9","Tissue RNA - testis [nTPM]":"11.8","Tissue RNA - thalamus [nTPM]":"5.3","Tissue RNA - thymus [nTPM]":"6.8","Tissue RNA - thyroid gland [nTPM]":"7.9","Tissue RNA - tongue [nTPM]":"4.6","Tissue RNA - tonsil [nTPM]":"4.6","Tissue RNA - urinary bladder [nTPM]":"5.6","Tissue RNA - vagina [nTPM]":"2.8","Tissue RNA - white matter [nTPM]":"7.7","Cell RNA - A-431 [nTPM]":"5.8","Cell RNA - A549 [nTPM]":"2.5","Cell RNA - AF22 [nTPM]":"10.0","Cell RNA - AN3-CA [nTPM]":"11.0","Cell RNA - ASC diff [nTPM]":"15.5","Cell RNA - ASC TERT1 [nTPM]":"17.1","Cell RNA - BEWO [nTPM]":"3.3","Cell RNA - BJ [nTPM]":"11.9","Cell RNA - BJ hTERT+ [nTPM]":"10.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.8","Cell RNA - CACO-2 [nTPM]":"3.3","Cell RNA - CAPAN-2 [nTPM]":"6.7","Cell RNA - Daudi [nTPM]":"15.4","Cell RNA - EFO-21 [nTPM]":"2.2","Cell RNA - fHDF\/TERT166 [nTPM]":"10.4","Cell RNA - GAMG [nTPM]":"9.0","Cell RNA - HaCaT [nTPM]":"1.9","Cell RNA - HAP1 [nTPM]":"9.7","Cell RNA - HBEC3-KT [nTPM]":"10.1","Cell RNA - HBF TERT88 [nTPM]":"10.5","Cell RNA - HDLM-2 [nTPM]":"16.9","Cell RNA - HEK 293 [nTPM]":"6.5","Cell RNA - HEL [nTPM]":"10.3","Cell RNA - HeLa [nTPM]":"10.4","Cell RNA - Hep G2 [nTPM]":"3.9","Cell RNA - HHSteC [nTPM]":"9.0","Cell RNA - HL-60 [nTPM]":"10.6","Cell RNA - HMC-1 [nTPM]":"7.9","Cell RNA - HSkMC [nTPM]":"13.7","Cell RNA - hTCEpi [nTPM]":"5.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.5","Cell RNA - hTERT-HME1 [nTPM]":"16.7","Cell RNA - hTERT-RPE1 [nTPM]":"19.1","Cell RNA - HUVEC TERT2 [nTPM]":"9.3","Cell RNA - JURKAT [nTPM]":"14.5","Cell RNA - K-562 [nTPM]":"18.6","Cell RNA - Karpas-707 [nTPM]":"28.2","Cell RNA - LHCN-M2 [nTPM]":"12.1","Cell RNA - MCF7 [nTPM]":"3.7","Cell RNA - MOLT-4 [nTPM]":"13.6","Cell RNA - NB-4 [nTPM]":"4.6","Cell RNA - NTERA-2 [nTPM]":"3.3","Cell RNA - OE19 [nTPM]":"3.6","Cell RNA - PC-3 [nTPM]":"6.0","Cell RNA - REH [nTPM]":"8.4","Cell RNA - RH-30 [nTPM]":"6.5","Cell RNA - RPMI-8226 [nTPM]":"4.9","Cell RNA - RPTEC TERT1 [nTPM]":"9.7","Cell RNA - RT4 [nTPM]":"6.8","Cell RNA - SCLC-21H [nTPM]":"11.0","Cell RNA - SH-SY5Y [nTPM]":"12.5","Cell RNA - SiHa [nTPM]":"8.6","Cell RNA - SK-BR-3 [nTPM]":"4.2","Cell RNA - SK-MEL-30 [nTPM]":"8.1","Cell RNA - SuSa [nTPM]":"7.7","Cell RNA - T-47d [nTPM]":"5.3","Cell RNA - THP-1 [nTPM]":"4.6","Cell RNA - TIME [nTPM]":"11.2","Cell RNA - U-138 MG [nTPM]":"6.0","Cell RNA - U-2 OS [nTPM]":"5.4","Cell RNA - U-2197 [nTPM]":"6.2","Cell RNA - U-251 MG [nTPM]":"8.1","Cell RNA - U-266\/70 [nTPM]":"11.3","Cell RNA - U-266\/84 [nTPM]":"18.6","Cell RNA - U-698 [nTPM]":"11.6","Cell RNA - U-87 MG [nTPM]":"9.7","Cell RNA - U-937 [nTPM]":"5.1","Cell RNA - WM-115 [nTPM]":"10.7","Blood RNA - basophil [nTPM]":"5.1","Blood RNA - classical monocyte [nTPM]":"0.9","Blood RNA - eosinophil [nTPM]":"0.9","Blood RNA - gdT-cell [nTPM]":"1.9","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"2.2","Blood RNA - memory B-cell [nTPM]":"2.0","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"1.2","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"2.0","Blood RNA - naive CD4 T-cell [nTPM]":"2.2","Blood RNA - naive CD8 T-cell [nTPM]":"2.3","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"0.7","Blood RNA - plasmacytoid DC [nTPM]":"1.6","Blood RNA - T-reg [nTPM]":"1.6","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"5.1","Brain RNA - basal ganglia [nTPM]":"6.8","Brain RNA - cerebellum [nTPM]":"7.1","Brain RNA - cerebral cortex [nTPM]":"5.3","Brain RNA - hippocampal formation [nTPM]":"3.5","Brain RNA - hypothalamus [nTPM]":"8.8","Brain RNA - medulla oblongata [nTPM]":"7.5","Brain RNA - midbrain [nTPM]":"7.7","Brain RNA - pons [nTPM]":"7.6","Brain RNA - spinal cord [nTPM]":"7.6","Brain RNA - thalamus [nTPM]":"5.3","Brain RNA - white matter [nTPM]":"7.7","Single Cell Type RNA - Adipocytes [nTPM]":"12.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.4","Single Cell Type RNA - Astrocytes [nTPM]":"162.6","Single Cell Type RNA - B-cells [nTPM]":"34.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.1","Single Cell Type RNA - Bipolar cells [nTPM]":"21.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"37.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"17.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.8","Single Cell Type RNA - dendritic cells [nTPM]":"17.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"10.4","Single Cell Type RNA - Early spermatids [nTPM]":"109.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"67.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.6","Single Cell Type RNA - Endothelial cells [nTPM]":"13.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"26.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"126.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.6","Single Cell Type RNA - Fibroblasts [nTPM]":"25.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"23.7","Single Cell Type RNA - granulocytes [nTPM]":"18.3","Single Cell Type RNA - Granulosa cells [nTPM]":"20.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.7","Single Cell Type RNA - Hepatocytes [nTPM]":"7.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.7","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"170.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.6","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"7.0","Single Cell Type RNA - Langerhans cells [nTPM]":"7.4","Single Cell Type RNA - Late spermatids [nTPM]":"48.2","Single Cell Type RNA - Leydig cells [nTPM]":"23.6","Single Cell Type RNA - Macrophages [nTPM]":"14.5","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"53.4","Single Cell Type RNA - monocytes [nTPM]":"6.6","Single Cell Type RNA - Muller glia cells [nTPM]":"26.1","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"115.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"196.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.9","Single Cell Type RNA - Paneth cells [nTPM]":"4.0","Single Cell Type RNA - Peritubular cells [nTPM]":"31.6","Single Cell Type RNA - Plasma cells [nTPM]":"23.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"68.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.9","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"32.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"25.5","Single Cell Type RNA - Spermatocytes [nTPM]":"67.9","Single Cell Type RNA - Spermatogonia [nTPM]":"37.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"29.6","Single Cell Type RNA - T-cells [nTPM]":"22.0","Single Cell Type RNA - Theca cells [nTPM]":"26.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.3","Single Cell Type RNA - Urothelial cells [nTPM]":"9.2"},{"Gene":"NEK10","Gene synonym":["FLJ32685"],"Ensembl":"ENSG00000163491","Gene description":"NIMA related kinase 10","Uniprot":["Q6ZWH5"],"Chromosome":"3","Position":"27110085-27369460","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Ciliopathy","Disease variant","Primary ciliary dyskinesia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"36.6","tongue":"20.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"87.6","Early spermatids":"123.5","Endometrial ciliated cells":"59.3","Excitatory neurons":"131.4","Inhibitory neurons":"130.2","Late spermatids":"61.7","Respiratory ciliated cells":"104.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"breast cancer":"1.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ":"6.0","LHCN-M2":"8.2","U-2 OS":"6.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038941"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA038941":"AB_10673600"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.20e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"3.0","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"5.3","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"14.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"9.4","Tissue RNA - cervix [nTPM]":"1.4","Tissue RNA - choroid plexus [nTPM]":"3.3","Tissue RNA - colon [nTPM]":"2.0","Tissue RNA - duodenum [nTPM]":"2.5","Tissue RNA - endometrium 1 [nTPM]":"0.8","Tissue RNA - epididymis [nTPM]":"8.3","Tissue RNA - esophagus [nTPM]":"1.8","Tissue RNA - fallopian tube [nTPM]":"11.0","Tissue RNA - gallbladder [nTPM]":"1.4","Tissue RNA - heart muscle [nTPM]":"3.3","Tissue RNA - hippocampal formation [nTPM]":"9.6","Tissue RNA - hypothalamus [nTPM]":"5.0","Tissue RNA - kidney [nTPM]":"1.7","Tissue RNA - liver [nTPM]":"2.5","Tissue RNA - lung [nTPM]":"2.4","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"3.3","Tissue RNA - midbrain [nTPM]":"5.7","Tissue RNA - ovary [nTPM]":"0.7","Tissue RNA - pancreas [nTPM]":"0.7","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"3.4","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"1.7","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"6.2","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"1.2","Tissue RNA - skeletal muscle [nTPM]":"12.4","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.8","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"2.3","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"1.0","Tissue RNA - testis [nTPM]":"36.6","Tissue RNA - thalamus [nTPM]":"6.1","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"20.0","Tissue RNA - tonsil [nTPM]":"0.6","Tissue RNA - urinary bladder [nTPM]":"1.2","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.9","Cell RNA - A-431 [nTPM]":"0.8","Cell RNA - A549 [nTPM]":"1.6","Cell RNA - AF22 [nTPM]":"0.8","Cell RNA - AN3-CA [nTPM]":"0.9","Cell RNA - ASC diff [nTPM]":"0.6","Cell RNA - ASC TERT1 [nTPM]":"1.5","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"6.0","Cell RNA - BJ hTERT+ [nTPM]":"0.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.4","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"1.4","Cell RNA - fHDF\/TERT166 [nTPM]":"2.5","Cell RNA - GAMG [nTPM]":"1.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.4","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"1.7","Cell RNA - HDLM-2 [nTPM]":"1.1","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"3.4","Cell RNA - Hep G2 [nTPM]":"2.9","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.8","Cell RNA - HSkMC [nTPM]":"1.8","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.5","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"2.0","Cell RNA - HUVEC TERT2 [nTPM]":"1.1","Cell RNA - JURKAT [nTPM]":"3.4","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.6","Cell RNA - LHCN-M2 [nTPM]":"8.2","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.6","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.8","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"3.0","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.9","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"4.8","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.7","Cell RNA - U-138 MG [nTPM]":"4.3","Cell RNA - U-2 OS [nTPM]":"6.8","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.6","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"3.6","Cell RNA - U-937 [nTPM]":"0.7","Cell RNA - WM-115 [nTPM]":"1.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.0","Brain RNA - basal ganglia [nTPM]":"5.3","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"9.4","Brain RNA - hippocampal formation [nTPM]":"9.6","Brain RNA - hypothalamus [nTPM]":"5.0","Brain RNA - medulla oblongata [nTPM]":"3.3","Brain RNA - midbrain [nTPM]":"5.7","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"2.3","Brain RNA - thalamus [nTPM]":"6.1","Brain RNA - white matter [nTPM]":"0.9","Single Cell Type RNA - Adipocytes [nTPM]":"1.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"11.4","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"14.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"9.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"87.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"123.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"59.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.3","Single Cell Type RNA - Endothelial cells [nTPM]":"2.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"131.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"3.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"1.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"130.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"61.7","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"1.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"32.8","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"1.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"2.7","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"104.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.4","Single Cell Type RNA - Spermatocytes [nTPM]":"32.2","Single Cell Type RNA - Spermatogonia [nTPM]":"2.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"3.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"NEK2","Gene synonym":["NEK2A","NLK1","PPP1R111","RP67"],"Ensembl":"ENSG00000117650","Gene description":"NIMA related kinase 2","Uniprot":["P51955"],"Chromosome":"1","Position":"211658657-211675630","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Chromosome partition","Meiosis","Mitosis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"bone marrow":"17.9","lymphoid tissue":"19.2","testis":"67.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"76.1","Spermatocytes":"244.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebellum":"5.7"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017530","HPA064967"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm","Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"CAB017530":"AB_1126558","HPA064967":"AB_2685393"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.47e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.11e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.7","Tissue RNA - adrenal gland [nTPM]":"0.4","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"5.3","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"17.9","Tissue RNA - breast [nTPM]":"1.5","Tissue RNA - cerebellum [nTPM]":"0.9","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"1.1","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"5.9","Tissue RNA - duodenum [nTPM]":"7.4","Tissue RNA - endometrium 1 [nTPM]":"1.3","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"4.4","Tissue RNA - fallopian tube [nTPM]":"2.2","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.7","Tissue RNA - lung [nTPM]":"0.7","Tissue RNA - lymph node [nTPM]":"9.0","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"3.2","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"2.5","Tissue RNA - rectum [nTPM]":"7.6","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"0.8","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"4.3","Tissue RNA - small intestine [nTPM]":"6.9","Tissue RNA - smooth muscle [nTPM]":"2.0","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"1.7","Tissue RNA - stomach 1 [nTPM]":"2.7","Tissue RNA - testis [nTPM]":"67.1","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"19.2","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"10.6","Tissue RNA - urinary bladder [nTPM]":"1.3","Tissue RNA - vagina [nTPM]":"1.6","Tissue RNA - white matter [nTPM]":"0.9","Cell RNA - A-431 [nTPM]":"86.0","Cell RNA - A549 [nTPM]":"60.5","Cell RNA - AF22 [nTPM]":"45.3","Cell RNA - AN3-CA [nTPM]":"32.6","Cell RNA - ASC diff [nTPM]":"2.6","Cell RNA - ASC TERT1 [nTPM]":"4.5","Cell RNA - BEWO [nTPM]":"49.7","Cell RNA - BJ [nTPM]":"32.4","Cell RNA - BJ hTERT+ [nTPM]":"30.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"55.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"47.5","Cell RNA - CACO-2 [nTPM]":"32.3","Cell RNA - CAPAN-2 [nTPM]":"81.7","Cell RNA - Daudi [nTPM]":"45.1","Cell RNA - EFO-21 [nTPM]":"15.2","Cell RNA - fHDF\/TERT166 [nTPM]":"25.2","Cell RNA - GAMG [nTPM]":"35.1","Cell RNA - HaCaT [nTPM]":"44.5","Cell RNA - HAP1 [nTPM]":"39.9","Cell RNA - HBEC3-KT [nTPM]":"24.2","Cell RNA - HBF TERT88 [nTPM]":"69.6","Cell RNA - HDLM-2 [nTPM]":"69.5","Cell RNA - HEK 293 [nTPM]":"33.2","Cell RNA - HEL [nTPM]":"21.6","Cell RNA - HeLa [nTPM]":"51.4","Cell RNA - Hep G2 [nTPM]":"44.2","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"43.2","Cell RNA - HMC-1 [nTPM]":"28.3","Cell RNA - HSkMC [nTPM]":"1.4","Cell RNA - hTCEpi [nTPM]":"2.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"42.9","Cell RNA - hTERT-HME1 [nTPM]":"45.9","Cell RNA - hTERT-RPE1 [nTPM]":"13.4","Cell RNA - HUVEC TERT2 [nTPM]":"36.3","Cell RNA - JURKAT [nTPM]":"45.2","Cell RNA - K-562 [nTPM]":"59.9","Cell RNA - Karpas-707 [nTPM]":"76.9","Cell RNA - LHCN-M2 [nTPM]":"56.0","Cell RNA - MCF7 [nTPM]":"23.6","Cell RNA - MOLT-4 [nTPM]":"47.3","Cell RNA - NB-4 [nTPM]":"28.8","Cell RNA - NTERA-2 [nTPM]":"43.0","Cell RNA - OE19 [nTPM]":"55.0","Cell RNA - PC-3 [nTPM]":"30.5","Cell RNA - REH [nTPM]":"46.2","Cell RNA - RH-30 [nTPM]":"69.2","Cell RNA - RPMI-8226 [nTPM]":"68.7","Cell RNA - RPTEC TERT1 [nTPM]":"19.7","Cell RNA - RT4 [nTPM]":"24.2","Cell RNA - SCLC-21H [nTPM]":"41.0","Cell RNA - SH-SY5Y [nTPM]":"45.0","Cell RNA - SiHa [nTPM]":"46.6","Cell RNA - SK-BR-3 [nTPM]":"51.5","Cell RNA - SK-MEL-30 [nTPM]":"39.3","Cell RNA - SuSa [nTPM]":"38.4","Cell RNA - T-47d [nTPM]":"79.4","Cell RNA - THP-1 [nTPM]":"25.1","Cell RNA - TIME [nTPM]":"19.0","Cell RNA - U-138 MG [nTPM]":"27.6","Cell RNA - U-2 OS [nTPM]":"54.1","Cell RNA - U-2197 [nTPM]":"54.8","Cell RNA - U-251 MG [nTPM]":"88.3","Cell RNA - U-266\/70 [nTPM]":"31.6","Cell RNA - U-266\/84 [nTPM]":"62.6","Cell RNA - U-698 [nTPM]":"59.6","Cell RNA - U-87 MG [nTPM]":"24.1","Cell RNA - U-937 [nTPM]":"32.6","Cell RNA - WM-115 [nTPM]":"46.8","Blood RNA - basophil [nTPM]":"1.2","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"1.6","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.9","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"0.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"1.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"11.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"76.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"39.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"0.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.8","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.2","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"2.5","Single Cell Type RNA - Langerhans cells [nTPM]":"1.1","Single Cell Type RNA - Late spermatids [nTPM]":"39.0","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"2.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.6","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"2.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"5.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.5","Single Cell Type RNA - Spermatocytes [nTPM]":"244.2","Single Cell Type RNA - Spermatogonia [nTPM]":"26.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - T-cells [nTPM]":"2.0","Single Cell Type RNA - Theca cells [nTPM]":"0.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.5","Single Cell Type RNA - Urothelial cells [nTPM]":"1.4"},{"Gene":"NEK8","Gene synonym":["NPHP9"],"Ensembl":"ENSG00000160602","Gene description":"NIMA related kinase 8","Uniprot":["Q86SG6"],"Chromosome":"17","Position":"28725897-28743455","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Ciliopathy","Disease variant","Nephronophthisis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"14.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040661","HPA040679"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Microtubules","Mitotic spindle"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 65: Plasmacytoid DCs - Unknown function","Subcellular main location":["Microtubules"],"Subcellular additional location":["Nuclear speckles","Mitotic spindle"],"Antibody RRID":{"HPA040661":"AB_10794065","HPA040679":"AB_10796226"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.98e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.52e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-3"},"Tissue RNA - adipose tissue [nTPM]":"1.5","Tissue RNA - adrenal gland [nTPM]":"3.1","Tissue RNA - amygdala [nTPM]":"1.7","Tissue RNA - appendix [nTPM]":"3.3","Tissue RNA - basal ganglia [nTPM]":"1.9","Tissue RNA - bone marrow [nTPM]":"1.7","Tissue RNA - breast [nTPM]":"2.4","Tissue RNA - cerebellum [nTPM]":"1.4","Tissue RNA - cerebral cortex [nTPM]":"1.9","Tissue RNA - cervix [nTPM]":"2.5","Tissue RNA - choroid plexus [nTPM]":"3.8","Tissue RNA - colon [nTPM]":"2.4","Tissue RNA - duodenum [nTPM]":"3.0","Tissue RNA - endometrium 1 [nTPM]":"1.5","Tissue RNA - epididymis [nTPM]":"3.2","Tissue RNA - esophagus [nTPM]":"2.5","Tissue RNA - fallopian tube [nTPM]":"3.9","Tissue RNA - gallbladder [nTPM]":"2.0","Tissue RNA - heart muscle [nTPM]":"1.0","Tissue RNA - hippocampal formation [nTPM]":"1.4","Tissue RNA - hypothalamus [nTPM]":"1.6","Tissue RNA - kidney [nTPM]":"9.1","Tissue RNA - liver [nTPM]":"5.2","Tissue RNA - lung [nTPM]":"3.3","Tissue RNA - lymph node [nTPM]":"5.8","Tissue RNA - medulla oblongata [nTPM]":"2.0","Tissue RNA - midbrain [nTPM]":"1.7","Tissue RNA - ovary [nTPM]":"1.9","Tissue RNA - pancreas [nTPM]":"4.5","Tissue RNA - parathyroid gland [nTPM]":"2.9","Tissue RNA - pituitary gland [nTPM]":"4.4","Tissue RNA - placenta [nTPM]":"2.6","Tissue RNA - pons [nTPM]":"1.7","Tissue RNA - prostate [nTPM]":"4.0","Tissue RNA - rectum [nTPM]":"2.2","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"3.7","Tissue RNA - seminal vesicle [nTPM]":"2.6","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"3.1","Tissue RNA - small intestine [nTPM]":"4.2","Tissue RNA - smooth muscle [nTPM]":"1.2","Tissue RNA - spinal cord [nTPM]":"1.6","Tissue RNA - spleen [nTPM]":"5.8","Tissue RNA - stomach 1 [nTPM]":"3.4","Tissue RNA - testis [nTPM]":"3.8","Tissue RNA - thalamus [nTPM]":"1.9","Tissue RNA - thymus [nTPM]":"2.7","Tissue RNA - thyroid gland [nTPM]":"7.2","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"5.0","Tissue RNA - urinary bladder [nTPM]":"2.6","Tissue RNA - vagina [nTPM]":"2.2","Tissue RNA - white matter [nTPM]":"2.3","Cell RNA - A-431 [nTPM]":"2.1","Cell RNA - A549 [nTPM]":"3.4","Cell RNA - AF22 [nTPM]":"3.5","Cell RNA - AN3-CA [nTPM]":"2.8","Cell RNA - ASC diff [nTPM]":"1.9","Cell RNA - ASC TERT1 [nTPM]":"2.1","Cell RNA - BEWO [nTPM]":"10.9","Cell RNA - BJ [nTPM]":"0.9","Cell RNA - BJ hTERT+ [nTPM]":"2.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.7","Cell RNA - CACO-2 [nTPM]":"5.4","Cell RNA - CAPAN-2 [nTPM]":"5.0","Cell RNA - Daudi [nTPM]":"13.1","Cell RNA - EFO-21 [nTPM]":"3.5","Cell RNA - fHDF\/TERT166 [nTPM]":"2.8","Cell RNA - GAMG [nTPM]":"2.5","Cell RNA - HaCaT [nTPM]":"3.8","Cell RNA - HAP1 [nTPM]":"5.2","Cell RNA - HBEC3-KT [nTPM]":"4.8","Cell RNA - HBF TERT88 [nTPM]":"1.3","Cell RNA - HDLM-2 [nTPM]":"3.5","Cell RNA - HEK 293 [nTPM]":"6.4","Cell RNA - HEL [nTPM]":"2.9","Cell RNA - HeLa [nTPM]":"5.8","Cell RNA - Hep G2 [nTPM]":"10.1","Cell RNA - HHSteC [nTPM]":"3.3","Cell RNA - HL-60 [nTPM]":"1.8","Cell RNA - HMC-1 [nTPM]":"3.7","Cell RNA - HSkMC [nTPM]":"4.8","Cell RNA - hTCEpi [nTPM]":"1.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.5","Cell RNA - hTERT-HME1 [nTPM]":"5.8","Cell RNA - hTERT-RPE1 [nTPM]":"1.8","Cell RNA - HUVEC TERT2 [nTPM]":"0.9","Cell RNA - JURKAT [nTPM]":"1.9","Cell RNA - K-562 [nTPM]":"4.3","Cell RNA - Karpas-707 [nTPM]":"1.3","Cell RNA - LHCN-M2 [nTPM]":"1.5","Cell RNA - MCF7 [nTPM]":"4.7","Cell RNA - MOLT-4 [nTPM]":"1.9","Cell RNA - NB-4 [nTPM]":"3.4","Cell RNA - NTERA-2 [nTPM]":"3.3","Cell RNA - OE19 [nTPM]":"3.7","Cell RNA - PC-3 [nTPM]":"1.0","Cell RNA - REH [nTPM]":"4.9","Cell RNA - RH-30 [nTPM]":"2.3","Cell RNA - RPMI-8226 [nTPM]":"5.9","Cell RNA - RPTEC TERT1 [nTPM]":"7.0","Cell RNA - RT4 [nTPM]":"5.7","Cell RNA - SCLC-21H [nTPM]":"6.4","Cell RNA - SH-SY5Y [nTPM]":"1.5","Cell RNA - SiHa [nTPM]":"3.0","Cell RNA - SK-BR-3 [nTPM]":"6.3","Cell RNA - SK-MEL-30 [nTPM]":"1.6","Cell RNA - SuSa [nTPM]":"4.7","Cell RNA - T-47d [nTPM]":"9.3","Cell RNA - THP-1 [nTPM]":"2.4","Cell RNA - TIME [nTPM]":"0.8","Cell RNA - U-138 MG [nTPM]":"1.3","Cell RNA - U-2 OS [nTPM]":"2.2","Cell RNA - U-2197 [nTPM]":"1.6","Cell RNA - U-251 MG [nTPM]":"1.0","Cell RNA - U-266\/70 [nTPM]":"1.5","Cell RNA - U-266\/84 [nTPM]":"1.8","Cell RNA - U-698 [nTPM]":"8.9","Cell RNA - U-87 MG [nTPM]":"2.0","Cell RNA - U-937 [nTPM]":"1.6","Cell RNA - WM-115 [nTPM]":"3.1","Blood RNA - basophil [nTPM]":"3.3","Blood RNA - classical monocyte [nTPM]":"0.9","Blood RNA - eosinophil [nTPM]":"1.2","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"2.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"4.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.0","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"1.3","Blood RNA - non-classical monocyte [nTPM]":"1.1","Blood RNA - plasmacytoid DC [nTPM]":"14.8","Blood RNA - T-reg [nTPM]":"0.5","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"1.7","Brain RNA - basal ganglia [nTPM]":"1.9","Brain RNA - cerebellum [nTPM]":"1.4","Brain RNA - cerebral cortex [nTPM]":"1.9","Brain RNA - hippocampal formation [nTPM]":"1.4","Brain RNA - hypothalamus [nTPM]":"1.6","Brain RNA - medulla oblongata [nTPM]":"2.0","Brain RNA - midbrain [nTPM]":"1.7","Brain RNA - pons [nTPM]":"1.7","Brain RNA - spinal cord [nTPM]":"1.6","Brain RNA - thalamus [nTPM]":"1.9","Brain RNA - white matter [nTPM]":"2.3","Single Cell Type RNA - Adipocytes [nTPM]":"2.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.3","Single Cell Type RNA - Astrocytes [nTPM]":"3.9","Single Cell Type RNA - B-cells [nTPM]":"22.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"2.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"11.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"17.6","Single Cell Type RNA - dendritic cells [nTPM]":"19.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.8","Single Cell Type RNA - Early spermatids [nTPM]":"9.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.0","Single Cell Type RNA - Endothelial cells [nTPM]":"2.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.3","Single Cell Type RNA - Erythroid cells [nTPM]":"7.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.2","Single Cell Type RNA - Fibroblasts [nTPM]":"3.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.2","Single Cell Type RNA - granulocytes [nTPM]":"26.6","Single Cell Type RNA - Granulosa cells [nTPM]":"3.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"9.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.9","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.4","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.0","Single Cell Type RNA - Langerhans cells [nTPM]":"2.7","Single Cell Type RNA - Late spermatids [nTPM]":"2.0","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"4.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"4.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.6","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.9","Single Cell Type RNA - Paneth cells [nTPM]":"17.2","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"7.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.0","Single Cell Type RNA - Spermatocytes [nTPM]":"19.9","Single Cell Type RNA - Spermatogonia [nTPM]":"11.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.1","Single Cell Type RNA - T-cells [nTPM]":"4.9","Single Cell Type RNA - Theca cells [nTPM]":"7.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.9","Single Cell Type RNA - Urothelial cells [nTPM]":"4.2"},{"Gene":"NEK9","Gene synonym":["DKFZp434D0935","MGC16714","Nek8","NERCC","NERCC1"],"Ensembl":"ENSG00000119638","Gene description":"NIMA related kinase 9","Uniprot":["Q8TD19"],"Chromosome":"14","Position":"75079353-75127344","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Cell cycle","Cell division","Mitosis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001405"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA001405":"AB_1079467"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.97e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.63e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Tissue RNA - adipose tissue [nTPM]":"24.2","Tissue RNA - adrenal gland [nTPM]":"18.5","Tissue RNA - amygdala [nTPM]":"6.7","Tissue RNA - appendix [nTPM]":"18.6","Tissue RNA - basal ganglia [nTPM]":"8.4","Tissue RNA - bone marrow [nTPM]":"11.8","Tissue RNA - breast [nTPM]":"17.3","Tissue RNA - cerebellum [nTPM]":"7.5","Tissue RNA - cerebral cortex [nTPM]":"7.9","Tissue RNA - cervix [nTPM]":"24.3","Tissue RNA - choroid plexus [nTPM]":"9.0","Tissue RNA - colon [nTPM]":"14.3","Tissue RNA - duodenum [nTPM]":"15.5","Tissue RNA - endometrium 1 [nTPM]":"26.0","Tissue RNA - epididymis [nTPM]":"10.5","Tissue RNA - esophagus [nTPM]":"17.8","Tissue RNA - fallopian tube [nTPM]":"25.2","Tissue RNA - gallbladder [nTPM]":"17.9","Tissue RNA - heart muscle [nTPM]":"37.2","Tissue RNA - hippocampal formation [nTPM]":"6.1","Tissue RNA - hypothalamus [nTPM]":"7.8","Tissue RNA - kidney [nTPM]":"18.4","Tissue RNA - liver [nTPM]":"21.0","Tissue RNA - lung [nTPM]":"18.8","Tissue RNA - lymph node [nTPM]":"21.0","Tissue RNA - medulla oblongata [nTPM]":"8.2","Tissue RNA - midbrain [nTPM]":"7.7","Tissue RNA - ovary [nTPM]":"35.8","Tissue RNA - pancreas [nTPM]":"16.0","Tissue RNA - parathyroid gland [nTPM]":"34.2","Tissue RNA - pituitary gland [nTPM]":"3.1","Tissue RNA - placenta [nTPM]":"21.2","Tissue RNA - pons [nTPM]":"7.9","Tissue RNA - prostate [nTPM]":"23.5","Tissue RNA - rectum [nTPM]":"16.3","Tissue RNA - retina [nTPM]":"16.5","Tissue RNA - salivary gland [nTPM]":"12.4","Tissue RNA - seminal vesicle [nTPM]":"28.1","Tissue RNA - skeletal muscle [nTPM]":"43.6","Tissue RNA - skin 1 [nTPM]":"8.1","Tissue RNA - small intestine [nTPM]":"16.9","Tissue RNA - smooth muscle [nTPM]":"32.2","Tissue RNA - spinal cord [nTPM]":"7.5","Tissue RNA - spleen [nTPM]":"19.7","Tissue RNA - stomach 1 [nTPM]":"13.1","Tissue RNA - testis [nTPM]":"20.4","Tissue RNA - thalamus [nTPM]":"7.7","Tissue RNA - thymus [nTPM]":"28.3","Tissue RNA - thyroid gland [nTPM]":"19.7","Tissue RNA - tongue [nTPM]":"36.9","Tissue RNA - tonsil [nTPM]":"23.5","Tissue RNA - urinary bladder [nTPM]":"16.3","Tissue RNA - vagina [nTPM]":"2.9","Tissue RNA - white matter [nTPM]":"9.1","Cell RNA - A-431 [nTPM]":"21.3","Cell RNA - A549 [nTPM]":"30.8","Cell RNA - AF22 [nTPM]":"44.8","Cell RNA - AN3-CA [nTPM]":"45.4","Cell RNA - ASC diff [nTPM]":"86.3","Cell RNA - ASC TERT1 [nTPM]":"88.8","Cell RNA - BEWO [nTPM]":"37.9","Cell RNA - BJ [nTPM]":"32.4","Cell RNA - BJ hTERT+ [nTPM]":"54.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"29.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"29.4","Cell RNA - CACO-2 [nTPM]":"25.5","Cell RNA - CAPAN-2 [nTPM]":"24.7","Cell RNA - Daudi [nTPM]":"52.7","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"54.2","Cell RNA - GAMG [nTPM]":"23.1","Cell RNA - HaCaT [nTPM]":"31.8","Cell RNA - HAP1 [nTPM]":"45.0","Cell RNA - HBEC3-KT [nTPM]":"27.0","Cell RNA - HBF TERT88 [nTPM]":"38.5","Cell RNA - HDLM-2 [nTPM]":"38.2","Cell RNA - HEK 293 [nTPM]":"16.8","Cell RNA - HEL [nTPM]":"23.0","Cell RNA - HeLa [nTPM]":"27.3","Cell RNA - Hep G2 [nTPM]":"17.3","Cell RNA - HHSteC [nTPM]":"48.6","Cell RNA - HL-60 [nTPM]":"10.8","Cell RNA - HMC-1 [nTPM]":"26.8","Cell RNA - HSkMC [nTPM]":"76.6","Cell RNA - hTCEpi [nTPM]":"32.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"31.8","Cell RNA - hTERT-HME1 [nTPM]":"26.7","Cell RNA - hTERT-RPE1 [nTPM]":"71.6","Cell RNA - HUVEC TERT2 [nTPM]":"46.1","Cell RNA - JURKAT [nTPM]":"36.2","Cell RNA - K-562 [nTPM]":"23.8","Cell RNA - Karpas-707 [nTPM]":"31.4","Cell RNA - LHCN-M2 [nTPM]":"40.2","Cell RNA - MCF7 [nTPM]":"4.8","Cell RNA - MOLT-4 [nTPM]":"35.5","Cell RNA - NB-4 [nTPM]":"11.5","Cell RNA - NTERA-2 [nTPM]":"21.9","Cell RNA - OE19 [nTPM]":"43.3","Cell RNA - PC-3 [nTPM]":"18.8","Cell RNA - REH [nTPM]":"53.5","Cell RNA - RH-30 [nTPM]":"49.4","Cell RNA - RPMI-8226 [nTPM]":"23.9","Cell RNA - RPTEC TERT1 [nTPM]":"21.3","Cell RNA - RT4 [nTPM]":"28.2","Cell RNA - SCLC-21H [nTPM]":"19.5","Cell RNA - SH-SY5Y [nTPM]":"41.3","Cell RNA - SiHa [nTPM]":"39.5","Cell RNA - SK-BR-3 [nTPM]":"19.3","Cell RNA - SK-MEL-30 [nTPM]":"30.0","Cell RNA - SuSa [nTPM]":"50.4","Cell RNA - T-47d [nTPM]":"41.7","Cell RNA - THP-1 [nTPM]":"37.6","Cell RNA - TIME [nTPM]":"46.3","Cell RNA - U-138 MG [nTPM]":"30.2","Cell RNA - U-2 OS [nTPM]":"12.7","Cell RNA - U-2197 [nTPM]":"31.5","Cell RNA - U-251 MG [nTPM]":"15.8","Cell RNA - U-266\/70 [nTPM]":"34.3","Cell RNA - U-266\/84 [nTPM]":"36.5","Cell RNA - U-698 [nTPM]":"49.6","Cell RNA - U-87 MG [nTPM]":"24.9","Cell RNA - U-937 [nTPM]":"24.8","Cell RNA - WM-115 [nTPM]":"26.4","Blood RNA - basophil [nTPM]":"3.4","Blood RNA - classical monocyte [nTPM]":"3.5","Blood RNA - eosinophil [nTPM]":"3.1","Blood RNA - gdT-cell [nTPM]":"2.5","Blood RNA - intermediate monocyte [nTPM]":"3.4","Blood RNA - MAIT T-cell [nTPM]":"4.0","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"2.4","Blood RNA - memory CD8 T-cell [nTPM]":"2.3","Blood RNA - myeloid DC [nTPM]":"5.0","Blood RNA - naive B-cell [nTPM]":"1.9","Blood RNA - naive CD4 T-cell [nTPM]":"3.1","Blood RNA - naive CD8 T-cell [nTPM]":"2.8","Blood RNA - neutrophil [nTPM]":"1.2","Blood RNA - NK-cell [nTPM]":"3.3","Blood RNA - non-classical monocyte [nTPM]":"2.5","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"1.5","Blood RNA - total PBMC [nTPM]":"2.9","Brain RNA - amygdala [nTPM]":"6.7","Brain RNA - basal ganglia [nTPM]":"8.4","Brain RNA - cerebellum [nTPM]":"7.5","Brain RNA - cerebral cortex [nTPM]":"7.9","Brain RNA - hippocampal formation [nTPM]":"6.1","Brain RNA - hypothalamus [nTPM]":"7.8","Brain RNA - medulla oblongata [nTPM]":"8.2","Brain RNA - midbrain [nTPM]":"7.7","Brain RNA - pons [nTPM]":"7.9","Brain RNA - spinal cord [nTPM]":"7.5","Brain RNA - thalamus [nTPM]":"7.7","Brain RNA - white matter [nTPM]":"9.1","Single Cell Type RNA - Adipocytes [nTPM]":"15.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"30.2","Single Cell Type RNA - Astrocytes [nTPM]":"49.3","Single Cell Type RNA - B-cells [nTPM]":"21.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.1","Single Cell Type RNA - Bipolar cells [nTPM]":"16.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"55.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"14.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"17.4","Single Cell Type RNA - dendritic cells [nTPM]":"11.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.9","Single Cell Type RNA - Early spermatids [nTPM]":"11.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.1","Single Cell Type RNA - Endothelial cells [nTPM]":"17.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"16.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"31.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"16.2","Single Cell Type RNA - Fibroblasts [nTPM]":"18.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.4","Single Cell Type RNA - granulocytes [nTPM]":"16.4","Single Cell Type RNA - Granulosa cells [nTPM]":"36.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.9","Single Cell Type RNA - Hepatocytes [nTPM]":"30.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.9","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"35.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.7","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"18.6","Single Cell Type RNA - Langerhans cells [nTPM]":"11.8","Single Cell Type RNA - Late spermatids [nTPM]":"8.3","Single Cell Type RNA - Leydig cells [nTPM]":"24.8","Single Cell Type RNA - Macrophages [nTPM]":"17.0","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"30.9","Single Cell Type RNA - monocytes [nTPM]":"16.0","Single Cell Type RNA - Muller glia cells [nTPM]":"12.0","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"41.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"59.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.3","Single Cell Type RNA - Paneth cells [nTPM]":"11.7","Single Cell Type RNA - Peritubular cells [nTPM]":"26.4","Single Cell Type RNA - Plasma cells [nTPM]":"14.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.7","Single Cell Type RNA - Spermatocytes [nTPM]":"28.8","Single Cell Type RNA - Spermatogonia [nTPM]":"13.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.0","Single Cell Type RNA - T-cells [nTPM]":"16.5","Single Cell Type RNA - Theca cells [nTPM]":"20.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.5","Single Cell Type RNA - Urothelial cells [nTPM]":"5.6"},{"Gene":"NEU1","Gene synonym":["NEU"],"Ensembl":"ENSG00000204386","Gene description":"Neuraminidase 1","Uniprot":["Q99519"],"Chromosome":"6","Position":"31857659-31862905","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism","Lipid degradation","Lipid metabolism"],"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"197.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"3.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"3.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"GAMG":"5.4","U-266\/84":"9.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015634","HPA021506"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"180000","Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA015634":"AB_1854386","HPA021506":"AB_1854385"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-3"},"Tissue RNA - adipose tissue [nTPM]":"23.9","Tissue RNA - adrenal gland [nTPM]":"57.2","Tissue RNA - amygdala [nTPM]":"0.7","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"0.8","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"22.4","Tissue RNA - cerebellum [nTPM]":"2.5","Tissue RNA - cerebral cortex [nTPM]":"1.2","Tissue RNA - cervix [nTPM]":"21.2","Tissue RNA - choroid plexus [nTPM]":"1.2","Tissue RNA - colon [nTPM]":"25.1","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"19.5","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"14.9","Tissue RNA - fallopian tube [nTPM]":"16.8","Tissue RNA - gallbladder [nTPM]":"1.0","Tissue RNA - heart muscle [nTPM]":"22.5","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"43.7","Tissue RNA - liver [nTPM]":"29.9","Tissue RNA - lung [nTPM]":"28.9","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"0.8","Tissue RNA - midbrain [nTPM]":"0.5","Tissue RNA - ovary [nTPM]":"20.3","Tissue RNA - pancreas [nTPM]":"35.9","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"33.0","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"0.8","Tissue RNA - prostate [nTPM]":"26.5","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"1.6","Tissue RNA - salivary gland [nTPM]":"38.6","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"21.3","Tissue RNA - skin 1 [nTPM]":"20.1","Tissue RNA - small intestine [nTPM]":"24.3","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"25.3","Tissue RNA - stomach 1 [nTPM]":"29.8","Tissue RNA - testis [nTPM]":"8.2","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"31.8","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"23.2","Tissue RNA - vagina [nTPM]":"16.2","Tissue RNA - white matter [nTPM]":"1.7","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.8","Cell RNA - AN3-CA [nTPM]":"1.4","Cell RNA - ASC diff [nTPM]":"1.8","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"0.7","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"1.5","Cell RNA - CAPAN-2 [nTPM]":"0.6","Cell RNA - Daudi [nTPM]":"0.7","Cell RNA - EFO-21 [nTPM]":"0.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"5.4","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"2.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"2.5","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"0.9","Cell RNA - Hep G2 [nTPM]":"1.2","Cell RNA - HHSteC [nTPM]":"1.4","Cell RNA - HL-60 [nTPM]":"0.9","Cell RNA - HMC-1 [nTPM]":"1.8","Cell RNA - HSkMC [nTPM]":"1.0","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.4","Cell RNA - hTERT-HME1 [nTPM]":"0.7","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.6","Cell RNA - JURKAT [nTPM]":"0.9","Cell RNA - K-562 [nTPM]":"1.1","Cell RNA - Karpas-707 [nTPM]":"1.2","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.6","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"0.5","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"0.9","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.9","Cell RNA - RPTEC TERT1 [nTPM]":"1.0","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"0.4","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.7","Cell RNA - SuSa [nTPM]":"0.9","Cell RNA - T-47d [nTPM]":"0.9","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"0.7","Cell RNA - U-138 MG [nTPM]":"1.1","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"0.7","Cell RNA - U-251 MG [nTPM]":"0.6","Cell RNA - U-266\/70 [nTPM]":"3.7","Cell RNA - U-266\/84 [nTPM]":"9.6","Cell RNA - U-698 [nTPM]":"0.9","Cell RNA - U-87 MG [nTPM]":"1.7","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"1.3","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"3.0","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.7","Brain RNA - basal ganglia [nTPM]":"0.8","Brain RNA - cerebellum [nTPM]":"2.5","Brain RNA - cerebral cortex [nTPM]":"1.2","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"0.8","Brain RNA - midbrain [nTPM]":"0.5","Brain RNA - pons [nTPM]":"0.8","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"1.7","Single Cell Type RNA - Adipocytes [nTPM]":"65.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"46.3","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"57.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"34.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"48.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"45.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"39.9","Single Cell Type RNA - Bipolar cells [nTPM]":"26.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"87.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"55.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"29.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"51.5","Single Cell Type RNA - Club cells [nTPM]":"54.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"47.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"62.8","Single Cell Type RNA - dendritic cells [nTPM]":"100.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"83.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"114.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"29.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"53.5","Single Cell Type RNA - Endothelial cells [nTPM]":"42.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"113.5","Single Cell Type RNA - Erythroid cells [nTPM]":"4.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"59.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"57.8","Single Cell Type RNA - Fibroblasts [nTPM]":"73.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"60.8","Single Cell Type RNA - granulocytes [nTPM]":"67.9","Single Cell Type RNA - Granulosa cells [nTPM]":"17.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"30.7","Single Cell Type RNA - Hepatocytes [nTPM]":"34.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"170.9","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"39.9","Single Cell Type RNA - Ionocytes [nTPM]":"79.3","Single Cell Type RNA - Kupffer cells [nTPM]":"63.0","Single Cell Type RNA - Langerhans cells [nTPM]":"65.9","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"27.7","Single Cell Type RNA - Macrophages [nTPM]":"93.0","Single Cell Type RNA - Melanocytes [nTPM]":"71.2","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"25.8","Single Cell Type RNA - Muller glia cells [nTPM]":"48.8","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"34.4","Single Cell Type RNA - Paneth cells [nTPM]":"88.1","Single Cell Type RNA - Peritubular cells [nTPM]":"23.3","Single Cell Type RNA - Plasma cells [nTPM]":"81.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"89.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"115.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"59.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"32.7","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"60.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"43.7","Single Cell Type RNA - Spermatocytes [nTPM]":"5.4","Single Cell Type RNA - Spermatogonia [nTPM]":"10.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"29.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"41.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"197.0","Single Cell Type RNA - T-cells [nTPM]":"81.7","Single Cell Type RNA - Theca cells [nTPM]":"40.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"41.1","Single Cell Type RNA - Urothelial cells [nTPM]":"34.6"},{"Gene":"NGLY1","Gene synonym":["FLJ11005","PNG-1","PNG1"],"Ensembl":"ENSG00000151092","Gene description":"N-glycanase 1","Uniprot":["Q96IV0"],"Chromosome":"3","Position":"25718944-25790039","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Early spermatids":"594.1","Late spermatids":"963.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036825"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036825":"AB_10672231"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.17e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.96e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.8","Tissue RNA - adrenal gland [nTPM]":"13.7","Tissue RNA - amygdala [nTPM]":"6.9","Tissue RNA - appendix [nTPM]":"15.1","Tissue RNA - basal ganglia [nTPM]":"7.1","Tissue RNA - bone marrow [nTPM]":"25.6","Tissue RNA - breast [nTPM]":"15.6","Tissue RNA - cerebellum [nTPM]":"10.0","Tissue RNA - cerebral cortex [nTPM]":"9.2","Tissue RNA - cervix [nTPM]":"12.3","Tissue RNA - choroid plexus [nTPM]":"10.5","Tissue RNA - colon [nTPM]":"17.9","Tissue RNA - duodenum [nTPM]":"14.6","Tissue RNA - endometrium 1 [nTPM]":"9.7","Tissue RNA - epididymis [nTPM]":"16.2","Tissue RNA - esophagus [nTPM]":"12.3","Tissue RNA - fallopian tube [nTPM]":"11.5","Tissue RNA - gallbladder [nTPM]":"9.8","Tissue RNA - heart muscle [nTPM]":"16.1","Tissue RNA - hippocampal formation [nTPM]":"7.5","Tissue RNA - hypothalamus [nTPM]":"8.0","Tissue RNA - kidney [nTPM]":"17.8","Tissue RNA - liver [nTPM]":"22.4","Tissue RNA - lung [nTPM]":"11.4","Tissue RNA - lymph node [nTPM]":"25.9","Tissue RNA - medulla oblongata [nTPM]":"8.1","Tissue RNA - midbrain [nTPM]":"9.2","Tissue RNA - ovary [nTPM]":"11.8","Tissue RNA - pancreas [nTPM]":"15.9","Tissue RNA - parathyroid gland [nTPM]":"11.6","Tissue RNA - pituitary gland [nTPM]":"5.9","Tissue RNA - placenta [nTPM]":"11.9","Tissue RNA - pons [nTPM]":"8.2","Tissue RNA - prostate [nTPM]":"14.2","Tissue RNA - rectum [nTPM]":"20.6","Tissue RNA - retina [nTPM]":"13.5","Tissue RNA - salivary gland [nTPM]":"14.9","Tissue RNA - seminal vesicle [nTPM]":"9.9","Tissue RNA - skeletal muscle [nTPM]":"49.5","Tissue RNA - skin 1 [nTPM]":"9.8","Tissue RNA - small intestine [nTPM]":"15.4","Tissue RNA - smooth muscle [nTPM]":"12.1","Tissue RNA - spinal cord [nTPM]":"6.7","Tissue RNA - spleen [nTPM]":"15.5","Tissue RNA - stomach 1 [nTPM]":"15.3","Tissue RNA - testis [nTPM]":"55.8","Tissue RNA - thalamus [nTPM]":"9.1","Tissue RNA - thymus [nTPM]":"27.4","Tissue RNA - thyroid gland [nTPM]":"13.6","Tissue RNA - tongue [nTPM]":"38.1","Tissue RNA - tonsil [nTPM]":"25.3","Tissue RNA - urinary bladder [nTPM]":"16.1","Tissue RNA - vagina [nTPM]":"9.9","Tissue RNA - white matter [nTPM]":"8.6","Cell RNA - A-431 [nTPM]":"27.6","Cell RNA - A549 [nTPM]":"24.2","Cell RNA - AF22 [nTPM]":"12.8","Cell RNA - AN3-CA [nTPM]":"27.4","Cell RNA - ASC diff [nTPM]":"23.5","Cell RNA - ASC TERT1 [nTPM]":"22.7","Cell RNA - BEWO [nTPM]":"15.0","Cell RNA - BJ [nTPM]":"21.6","Cell RNA - BJ hTERT+ [nTPM]":"20.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"29.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"25.5","Cell RNA - CACO-2 [nTPM]":"14.8","Cell RNA - CAPAN-2 [nTPM]":"20.9","Cell RNA - Daudi [nTPM]":"64.3","Cell RNA - EFO-21 [nTPM]":"24.5","Cell RNA - fHDF\/TERT166 [nTPM]":"19.9","Cell RNA - GAMG [nTPM]":"28.3","Cell RNA - HaCaT [nTPM]":"12.1","Cell RNA - HAP1 [nTPM]":"45.5","Cell RNA - HBEC3-KT [nTPM]":"14.0","Cell RNA - HBF TERT88 [nTPM]":"39.2","Cell RNA - HDLM-2 [nTPM]":"27.8","Cell RNA - HEK 293 [nTPM]":"18.5","Cell RNA - HEL [nTPM]":"49.9","Cell RNA - HeLa [nTPM]":"15.1","Cell RNA - Hep G2 [nTPM]":"24.8","Cell RNA - HHSteC [nTPM]":"29.0","Cell RNA - HL-60 [nTPM]":"48.3","Cell RNA - HMC-1 [nTPM]":"25.7","Cell RNA - HSkMC [nTPM]":"20.3","Cell RNA - hTCEpi [nTPM]":"17.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"33.6","Cell RNA - hTERT-HME1 [nTPM]":"31.5","Cell RNA - hTERT-RPE1 [nTPM]":"32.2","Cell RNA - HUVEC TERT2 [nTPM]":"31.3","Cell RNA - JURKAT [nTPM]":"32.8","Cell RNA - K-562 [nTPM]":"47.9","Cell RNA - Karpas-707 [nTPM]":"49.1","Cell RNA - LHCN-M2 [nTPM]":"30.3","Cell RNA - MCF7 [nTPM]":"11.7","Cell RNA - MOLT-4 [nTPM]":"60.7","Cell RNA - NB-4 [nTPM]":"26.8","Cell RNA - NTERA-2 [nTPM]":"17.4","Cell RNA - OE19 [nTPM]":"33.2","Cell RNA - PC-3 [nTPM]":"43.5","Cell RNA - REH [nTPM]":"54.2","Cell RNA - RH-30 [nTPM]":"16.5","Cell RNA - RPMI-8226 [nTPM]":"54.6","Cell RNA - RPTEC TERT1 [nTPM]":"27.1","Cell RNA - RT4 [nTPM]":"31.1","Cell RNA - SCLC-21H [nTPM]":"8.3","Cell RNA - SH-SY5Y [nTPM]":"9.5","Cell RNA - SiHa [nTPM]":"35.1","Cell RNA - SK-BR-3 [nTPM]":"33.3","Cell RNA - SK-MEL-30 [nTPM]":"23.3","Cell RNA - SuSa [nTPM]":"24.0","Cell RNA - T-47d [nTPM]":"31.1","Cell RNA - THP-1 [nTPM]":"40.6","Cell RNA - TIME [nTPM]":"15.7","Cell RNA - U-138 MG [nTPM]":"15.5","Cell RNA - U-2 OS [nTPM]":"20.1","Cell RNA - U-2197 [nTPM]":"27.5","Cell RNA - U-251 MG [nTPM]":"29.9","Cell RNA - U-266\/70 [nTPM]":"60.4","Cell RNA - U-266\/84 [nTPM]":"60.7","Cell RNA - U-698 [nTPM]":"48.8","Cell RNA - U-87 MG [nTPM]":"25.1","Cell RNA - U-937 [nTPM]":"52.8","Cell RNA - WM-115 [nTPM]":"18.1","Blood RNA - basophil [nTPM]":"48.8","Blood RNA - classical monocyte [nTPM]":"19.7","Blood RNA - eosinophil [nTPM]":"27.8","Blood RNA - gdT-cell [nTPM]":"22.9","Blood RNA - intermediate monocyte [nTPM]":"19.4","Blood RNA - MAIT T-cell [nTPM]":"26.0","Blood RNA - memory B-cell [nTPM]":"42.2","Blood RNA - memory CD4 T-cell [nTPM]":"23.2","Blood RNA - memory CD8 T-cell [nTPM]":"23.5","Blood RNA - myeloid DC [nTPM]":"31.6","Blood RNA - naive B-cell [nTPM]":"33.4","Blood RNA - naive CD4 T-cell [nTPM]":"21.8","Blood RNA - naive CD8 T-cell [nTPM]":"23.6","Blood RNA - neutrophil [nTPM]":"18.3","Blood RNA - NK-cell [nTPM]":"45.0","Blood RNA - non-classical monocyte [nTPM]":"16.0","Blood RNA - plasmacytoid DC [nTPM]":"65.1","Blood RNA - T-reg [nTPM]":"19.0","Blood RNA - total PBMC [nTPM]":"20.7","Brain RNA - amygdala [nTPM]":"6.9","Brain RNA - basal ganglia [nTPM]":"7.1","Brain RNA - cerebellum [nTPM]":"10.0","Brain RNA - cerebral cortex [nTPM]":"9.2","Brain RNA - hippocampal formation [nTPM]":"7.5","Brain RNA - hypothalamus [nTPM]":"8.0","Brain RNA - medulla oblongata [nTPM]":"8.1","Brain RNA - midbrain [nTPM]":"9.2","Brain RNA - pons [nTPM]":"8.2","Brain RNA - spinal cord [nTPM]":"6.7","Brain RNA - thalamus [nTPM]":"9.1","Brain RNA - white matter [nTPM]":"8.6","Single Cell Type RNA - Adipocytes [nTPM]":"24.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.3","Single Cell Type RNA - Astrocytes [nTPM]":"34.0","Single Cell Type RNA - B-cells [nTPM]":"84.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"25.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"16.5","Single Cell Type RNA - Bipolar cells [nTPM]":"22.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"30.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"21.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"40.5","Single Cell Type RNA - dendritic cells [nTPM]":"74.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"25.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"30.6","Single Cell Type RNA - Early spermatids [nTPM]":"594.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.4","Single Cell Type RNA - Endothelial cells [nTPM]":"20.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"26.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"51.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"44.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"31.7","Single Cell Type RNA - Fibroblasts [nTPM]":"19.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.2","Single Cell Type RNA - granulocytes [nTPM]":"20.8","Single Cell Type RNA - Granulosa cells [nTPM]":"77.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.5","Single Cell Type RNA - Hepatocytes [nTPM]":"25.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.4","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"64.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"29.3","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"22.2","Single Cell Type RNA - Langerhans cells [nTPM]":"63.6","Single Cell Type RNA - Late spermatids [nTPM]":"963.6","Single Cell Type RNA - Leydig cells [nTPM]":"14.9","Single Cell Type RNA - Macrophages [nTPM]":"33.6","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"31.9","Single Cell Type RNA - monocytes [nTPM]":"30.0","Single Cell Type RNA - Muller glia cells [nTPM]":"20.7","Single Cell Type RNA - NK-cells [nTPM]":"45.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"54.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"59.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"27.2","Single Cell Type RNA - Paneth cells [nTPM]":"27.3","Single Cell Type RNA - Peritubular cells [nTPM]":"15.8","Single Cell Type RNA - Plasma cells [nTPM]":"87.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"27.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"26.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"38.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"25.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"22.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"26.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.9","Single Cell Type RNA - Spermatocytes [nTPM]":"105.7","Single Cell Type RNA - Spermatogonia [nTPM]":"52.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"56.6","Single Cell Type RNA - T-cells [nTPM]":"41.1","Single Cell Type RNA - Theca cells [nTPM]":"26.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"30.3","Single Cell Type RNA - Urothelial cells [nTPM]":"20.6"},{"Gene":"NHLRC1","Gene synonym":["bA204B7.2","EPM2B"],"Ensembl":"ENSG00000187566","Gene description":"NHL repeat containing E3 ubiquitin protein ligase 1","Uniprot":["Q6VVB1"],"Chromosome":"6","Position":"18120440-18122677","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Autophagy","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"5.0","Exocrine glandular cells":"3.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"6.8","K-562":"6.1","SCLC-21H":"6.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066030"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA066030":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.01e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.30e-4"},"Tissue RNA - adipose tissue [nTPM]":"1.2","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"2.0","Tissue RNA - appendix [nTPM]":"0.8","Tissue RNA - basal ganglia [nTPM]":"2.3","Tissue RNA - bone marrow [nTPM]":"1.1","Tissue RNA - breast [nTPM]":"2.0","Tissue RNA - cerebellum [nTPM]":"1.5","Tissue RNA - cerebral cortex [nTPM]":"2.6","Tissue RNA - cervix [nTPM]":"0.8","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"1.5","Tissue RNA - duodenum [nTPM]":"1.4","Tissue RNA - endometrium 1 [nTPM]":"0.8","Tissue RNA - epididymis [nTPM]":"2.6","Tissue RNA - esophagus [nTPM]":"1.1","Tissue RNA - fallopian tube [nTPM]":"1.4","Tissue RNA - gallbladder [nTPM]":"0.6","Tissue RNA - heart muscle [nTPM]":"1.8","Tissue RNA - hippocampal formation [nTPM]":"2.4","Tissue RNA - hypothalamus [nTPM]":"1.9","Tissue RNA - kidney [nTPM]":"0.8","Tissue RNA - liver [nTPM]":"4.1","Tissue RNA - lung [nTPM]":"1.2","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"2.5","Tissue RNA - midbrain [nTPM]":"1.8","Tissue RNA - ovary [nTPM]":"1.4","Tissue RNA - pancreas [nTPM]":"1.8","Tissue RNA - parathyroid gland [nTPM]":"1.2","Tissue RNA - pituitary gland [nTPM]":"1.2","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"1.2","Tissue RNA - rectum [nTPM]":"1.3","Tissue RNA - retina [nTPM]":"2.0","Tissue RNA - salivary gland [nTPM]":"2.3","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"2.6","Tissue RNA - skin 1 [nTPM]":"3.8","Tissue RNA - small intestine [nTPM]":"1.9","Tissue RNA - smooth muscle [nTPM]":"0.8","Tissue RNA - spinal cord [nTPM]":"1.6","Tissue RNA - spleen [nTPM]":"1.1","Tissue RNA - stomach 1 [nTPM]":"1.3","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"2.0","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"1.6","Tissue RNA - tongue [nTPM]":"1.5","Tissue RNA - tonsil [nTPM]":"0.8","Tissue RNA - urinary bladder [nTPM]":"0.9","Tissue RNA - vagina [nTPM]":"0.8","Tissue RNA - white matter [nTPM]":"3.6","Cell RNA - A-431 [nTPM]":"2.6","Cell RNA - A549 [nTPM]":"1.5","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"1.3","Cell RNA - ASC TERT1 [nTPM]":"1.2","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"2.6","Cell RNA - BJ hTERT+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.5","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"2.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"6.8","Cell RNA - fHDF\/TERT166 [nTPM]":"1.9","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"3.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"1.7","Cell RNA - HBF TERT88 [nTPM]":"0.7","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.9","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"1.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"2.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.7","Cell RNA - HSkMC [nTPM]":"2.1","Cell RNA - hTCEpi [nTPM]":"2.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.0","Cell RNA - hTERT-HME1 [nTPM]":"0.9","Cell RNA - hTERT-RPE1 [nTPM]":"0.6","Cell RNA - HUVEC TERT2 [nTPM]":"2.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"6.1","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"2.1","Cell RNA - MCF7 [nTPM]":"2.8","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"1.5","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"1.4","Cell RNA - RT4 [nTPM]":"2.8","Cell RNA - SCLC-21H [nTPM]":"6.1","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"5.3","Cell RNA - SK-BR-3 [nTPM]":"4.3","Cell RNA - SK-MEL-30 [nTPM]":"1.6","Cell RNA - SuSa [nTPM]":"0.6","Cell RNA - T-47d [nTPM]":"3.1","Cell RNA - THP-1 [nTPM]":"1.7","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"1.3","Cell RNA - U-2197 [nTPM]":"1.8","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"2.6","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"4.4","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"4.9","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"2.3","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"4.7","Blood RNA - naive B-cell [nTPM]":"1.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.5","Blood RNA - naive CD8 T-cell [nTPM]":"1.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"1.6","Blood RNA - non-classical monocyte [nTPM]":"2.3","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"1.3","Blood RNA - total PBMC [nTPM]":"1.8","Brain RNA - amygdala [nTPM]":"2.0","Brain RNA - basal ganglia [nTPM]":"2.3","Brain RNA - cerebellum [nTPM]":"1.5","Brain RNA - cerebral cortex [nTPM]":"2.6","Brain RNA - hippocampal formation [nTPM]":"2.4","Brain RNA - hypothalamus [nTPM]":"1.9","Brain RNA - medulla oblongata [nTPM]":"2.5","Brain RNA - midbrain [nTPM]":"1.8","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"1.6","Brain RNA - thalamus [nTPM]":"2.0","Brain RNA - white matter [nTPM]":"3.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"2.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.5","Single Cell Type RNA - Erythroid cells [nTPM]":"5.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"1.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"1.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.5","Single Cell Type RNA - Muller glia cells [nTPM]":"1.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"1.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.5"},{"Gene":"NIPA1","Gene synonym":["MGC35570","SLC57A1","SPG6"],"Ensembl":"ENSG00000170113","Gene description":"NIPA magnesium transporter 1","Uniprot":["Q7RTP0"],"Chromosome":"15","Position":"22773063-22829789","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"40.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"36.2","Inhibitory neurons":"33.8","Oligodendrocytes":"65.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"3.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023269"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA023269":"AB_1854485"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.1","Tissue RNA - adrenal gland [nTPM]":"4.2","Tissue RNA - amygdala [nTPM]":"27.7","Tissue RNA - appendix [nTPM]":"3.7","Tissue RNA - basal ganglia [nTPM]":"36.9","Tissue RNA - bone marrow [nTPM]":"1.2","Tissue RNA - breast [nTPM]":"2.8","Tissue RNA - cerebellum [nTPM]":"36.8","Tissue RNA - cerebral cortex [nTPM]":"38.1","Tissue RNA - cervix [nTPM]":"3.7","Tissue RNA - choroid plexus [nTPM]":"17.9","Tissue RNA - colon [nTPM]":"4.6","Tissue RNA - duodenum [nTPM]":"6.5","Tissue RNA - endometrium 1 [nTPM]":"2.2","Tissue RNA - epididymis [nTPM]":"2.1","Tissue RNA - esophagus [nTPM]":"4.3","Tissue RNA - fallopian tube [nTPM]":"2.5","Tissue RNA - gallbladder [nTPM]":"4.8","Tissue RNA - heart muscle [nTPM]":"3.5","Tissue RNA - hippocampal formation [nTPM]":"22.8","Tissue RNA - hypothalamus [nTPM]":"28.7","Tissue RNA - kidney [nTPM]":"6.2","Tissue RNA - liver [nTPM]":"5.7","Tissue RNA - lung [nTPM]":"4.7","Tissue RNA - lymph node [nTPM]":"5.3","Tissue RNA - medulla oblongata [nTPM]":"35.4","Tissue RNA - midbrain [nTPM]":"36.9","Tissue RNA - ovary [nTPM]":"1.5","Tissue RNA - pancreas [nTPM]":"5.7","Tissue RNA - parathyroid gland [nTPM]":"8.7","Tissue RNA - pituitary gland [nTPM]":"3.6","Tissue RNA - placenta [nTPM]":"3.5","Tissue RNA - pons [nTPM]":"33.8","Tissue RNA - prostate [nTPM]":"6.7","Tissue RNA - rectum [nTPM]":"4.3","Tissue RNA - retina [nTPM]":"6.2","Tissue RNA - salivary gland [nTPM]":"3.6","Tissue RNA - seminal vesicle [nTPM]":"3.4","Tissue RNA - skeletal muscle [nTPM]":"2.5","Tissue RNA - skin 1 [nTPM]":"4.9","Tissue RNA - small intestine [nTPM]":"6.6","Tissue RNA - smooth muscle [nTPM]":"2.6","Tissue RNA - spinal cord [nTPM]":"36.1","Tissue RNA - spleen [nTPM]":"4.2","Tissue RNA - stomach 1 [nTPM]":"6.4","Tissue RNA - testis [nTPM]":"4.3","Tissue RNA - thalamus [nTPM]":"36.0","Tissue RNA - thymus [nTPM]":"8.2","Tissue RNA - thyroid gland [nTPM]":"7.3","Tissue RNA - tongue [nTPM]":"3.5","Tissue RNA - tonsil [nTPM]":"5.5","Tissue RNA - urinary bladder [nTPM]":"3.2","Tissue RNA - vagina [nTPM]":"3.5","Tissue RNA - white matter [nTPM]":"40.2","Cell RNA - A-431 [nTPM]":"14.9","Cell RNA - A549 [nTPM]":"17.4","Cell RNA - AF22 [nTPM]":"5.4","Cell RNA - AN3-CA [nTPM]":"12.4","Cell RNA - ASC diff [nTPM]":"6.9","Cell RNA - ASC TERT1 [nTPM]":"5.6","Cell RNA - BEWO [nTPM]":"3.8","Cell RNA - BJ [nTPM]":"17.6","Cell RNA - BJ hTERT+ [nTPM]":"12.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.1","Cell RNA - CACO-2 [nTPM]":"13.3","Cell RNA - CAPAN-2 [nTPM]":"7.4","Cell RNA - Daudi [nTPM]":"6.9","Cell RNA - EFO-21 [nTPM]":"13.5","Cell RNA - fHDF\/TERT166 [nTPM]":"7.3","Cell RNA - GAMG [nTPM]":"17.4","Cell RNA - HaCaT [nTPM]":"9.7","Cell RNA - HAP1 [nTPM]":"16.0","Cell RNA - HBEC3-KT [nTPM]":"4.6","Cell RNA - HBF TERT88 [nTPM]":"10.1","Cell RNA - HDLM-2 [nTPM]":"40.2","Cell RNA - HEK 293 [nTPM]":"9.8","Cell RNA - HEL [nTPM]":"10.8","Cell RNA - HeLa [nTPM]":"10.8","Cell RNA - Hep G2 [nTPM]":"11.4","Cell RNA - HHSteC [nTPM]":"8.3","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"20.8","Cell RNA - HSkMC [nTPM]":"1.7","Cell RNA - hTCEpi [nTPM]":"15.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.5","Cell RNA - hTERT-HME1 [nTPM]":"9.2","Cell RNA - hTERT-RPE1 [nTPM]":"13.6","Cell RNA - HUVEC TERT2 [nTPM]":"8.2","Cell RNA - JURKAT [nTPM]":"15.2","Cell RNA - K-562 [nTPM]":"8.4","Cell RNA - Karpas-707 [nTPM]":"11.3","Cell RNA - LHCN-M2 [nTPM]":"4.8","Cell RNA - MCF7 [nTPM]":"5.6","Cell RNA - MOLT-4 [nTPM]":"5.9","Cell RNA - NB-4 [nTPM]":"9.7","Cell RNA - NTERA-2 [nTPM]":"5.9","Cell RNA - OE19 [nTPM]":"15.9","Cell RNA - PC-3 [nTPM]":"18.2","Cell RNA - REH [nTPM]":"12.1","Cell RNA - RH-30 [nTPM]":"7.7","Cell RNA - RPMI-8226 [nTPM]":"5.4","Cell RNA - RPTEC TERT1 [nTPM]":"13.0","Cell RNA - RT4 [nTPM]":"14.9","Cell RNA - SCLC-21H [nTPM]":"15.2","Cell RNA - SH-SY5Y [nTPM]":"15.4","Cell RNA - SiHa [nTPM]":"13.2","Cell RNA - SK-BR-3 [nTPM]":"1.6","Cell RNA - SK-MEL-30 [nTPM]":"16.7","Cell RNA - SuSa [nTPM]":"7.0","Cell RNA - T-47d [nTPM]":"10.3","Cell RNA - THP-1 [nTPM]":"13.8","Cell RNA - TIME [nTPM]":"15.4","Cell RNA - U-138 MG [nTPM]":"23.9","Cell RNA - U-2 OS [nTPM]":"12.2","Cell RNA - U-2197 [nTPM]":"10.1","Cell RNA - U-251 MG [nTPM]":"27.2","Cell RNA - U-266\/70 [nTPM]":"12.7","Cell RNA - U-266\/84 [nTPM]":"13.6","Cell RNA - U-698 [nTPM]":"12.4","Cell RNA - U-87 MG [nTPM]":"12.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"15.6","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"0.7","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"3.9","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"27.7","Brain RNA - basal ganglia [nTPM]":"36.9","Brain RNA - cerebellum [nTPM]":"36.8","Brain RNA - cerebral cortex [nTPM]":"38.1","Brain RNA - hippocampal formation [nTPM]":"22.8","Brain RNA - hypothalamus [nTPM]":"28.7","Brain RNA - medulla oblongata [nTPM]":"35.4","Brain RNA - midbrain [nTPM]":"36.9","Brain RNA - pons [nTPM]":"33.8","Brain RNA - spinal cord [nTPM]":"36.1","Brain RNA - thalamus [nTPM]":"36.0","Brain RNA - white matter [nTPM]":"40.2","Single Cell Type RNA - Adipocytes [nTPM]":"5.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.9","Single Cell Type RNA - Astrocytes [nTPM]":"14.4","Single Cell Type RNA - B-cells [nTPM]":"7.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"4.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"5.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.6","Single Cell Type RNA - dendritic cells [nTPM]":"10.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.7","Single Cell Type RNA - Early spermatids [nTPM]":"3.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.4","Single Cell Type RNA - Endothelial cells [nTPM]":"5.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"4.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"36.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.1","Single Cell Type RNA - Fibroblasts [nTPM]":"4.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"4.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.6","Single Cell Type RNA - Hepatocytes [nTPM]":"6.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.1","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"33.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.1","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.4","Single Cell Type RNA - Langerhans cells [nTPM]":"6.9","Single Cell Type RNA - Late spermatids [nTPM]":"4.2","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"2.9","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"3.8","Single Cell Type RNA - Muller glia cells [nTPM]":"4.7","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"65.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.7","Single Cell Type RNA - Paneth cells [nTPM]":"6.8","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"7.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.6","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.6","Single Cell Type RNA - Spermatocytes [nTPM]":"3.4","Single Cell Type RNA - Spermatogonia [nTPM]":"8.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - T-cells [nTPM]":"7.1","Single Cell Type RNA - Theca cells [nTPM]":"1.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.5","Single Cell Type RNA - Urothelial cells [nTPM]":"7.3"},{"Gene":"NIPAL4","Gene synonym":["ICHYN"],"Ensembl":"ENSG00000172548","Gene description":"NIPA like domain containing 4","Uniprot":["Q0D2K0"],"Chromosome":"5","Position":"157460213-157474722","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Receptor"],"Disease involvement":["Disease variant","Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"18.7","skin 1":"61.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"29.7","Basal prostatic cells":"9.8","Oligodendrocytes":"21.0","Squamous epithelial cells":"9.8","Suprabasal keratinocytes":"42.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"17.0","urothelial cancer":"11.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"25","RNA blood cell specific nTPM":{"memory B-cell":"1.6","naive B-cell":"4.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"37","RNA blood lineage specific nTPM":{"B-cells":"4.8"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"hTCEpi":"31.7","RT4":"108.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038259"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 28: Keratinocytes - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038259":"AB_10672510"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.74e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.82e-4"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"3.5","Tissue RNA - appendix [nTPM]":"2.0","Tissue RNA - basal ganglia [nTPM]":"9.7","Tissue RNA - bone marrow [nTPM]":"3.4","Tissue RNA - breast [nTPM]":"2.2","Tissue RNA - cerebellum [nTPM]":"8.5","Tissue RNA - cerebral cortex [nTPM]":"7.1","Tissue RNA - cervix [nTPM]":"5.9","Tissue RNA - choroid plexus [nTPM]":"1.1","Tissue RNA - colon [nTPM]":"3.7","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"1.2","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"15.1","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"1.5","Tissue RNA - hippocampal formation [nTPM]":"3.9","Tissue RNA - hypothalamus [nTPM]":"6.2","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.7","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"12.4","Tissue RNA - midbrain [nTPM]":"8.7","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"10.5","Tissue RNA - prostate [nTPM]":"1.5","Tissue RNA - rectum [nTPM]":"0.6","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"1.9","Tissue RNA - seminal vesicle [nTPM]":"1.4","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"61.2","Tissue RNA - small intestine [nTPM]":"0.9","Tissue RNA - smooth muscle [nTPM]":"1.1","Tissue RNA - spinal cord [nTPM]":"7.6","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"2.5","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"8.0","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"5.8","Tissue RNA - urinary bladder [nTPM]":"11.5","Tissue RNA - vagina [nTPM]":"15.1","Tissue RNA - white matter [nTPM]":"18.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"5.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.9","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"1.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"6.3","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"2.7","Cell RNA - HBF TERT88 [nTPM]":"0.6","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.6","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"31.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"1.3","Cell RNA - hTERT-RPE1 [nTPM]":"1.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"1.8","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"108.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.4","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"8.5","Cell RNA - T-47d [nTPM]":"1.6","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"3.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.9","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"1.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"4.8","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"3.5","Brain RNA - basal ganglia [nTPM]":"9.7","Brain RNA - cerebellum [nTPM]":"8.5","Brain RNA - cerebral cortex [nTPM]":"7.1","Brain RNA - hippocampal formation [nTPM]":"3.9","Brain RNA - hypothalamus [nTPM]":"6.2","Brain RNA - medulla oblongata [nTPM]":"12.4","Brain RNA - midbrain [nTPM]":"8.7","Brain RNA - pons [nTPM]":"10.5","Brain RNA - spinal cord [nTPM]":"7.6","Brain RNA - thalamus [nTPM]":"8.0","Brain RNA - white matter [nTPM]":"18.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"29.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"42.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"4.4"},{"Gene":"NKAIN2","Gene synonym":["FAM77B","TCBA1"],"Ensembl":"ENSG00000188580","Gene description":"Sodium\/potassium transporting ATPase interacting 2","Uniprot":["Q5VXU1"],"Chromosome":"6","Position":"123803865-124825640","Protein class":["Disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"56.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"1721.6","Inhibitory neurons":"636.4","Oligodendrocytes":"2869.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"19","RNA blood cell specific nTPM":{"basophil":"1.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"granulocytes":"1.8"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"2.1","Daudi":"3.0","HEL":"6.4","Karpas-707":"10.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045860"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA045860":"AB_10983192"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.9","Tissue RNA - adrenal gland [nTPM]":"0.4","Tissue RNA - amygdala [nTPM]":"24.2","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"33.6","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"30.1","Tissue RNA - cerebral cortex [nTPM]":"39.3","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"9.8","Tissue RNA - colon [nTPM]":"1.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"1.1","Tissue RNA - hippocampal formation [nTPM]":"29.2","Tissue RNA - hypothalamus [nTPM]":"25.3","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"40.7","Tissue RNA - midbrain [nTPM]":"28.0","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.8","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"37.4","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"6.6","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"2.9","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"34.8","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"28.8","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"3.4","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.5","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"56.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"1.6","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"2.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"3.0","Cell RNA - EFO-21 [nTPM]":"0.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.1","Cell RNA - HEL [nTPM]":"6.4","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"1.2","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"10.5","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"1.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"1.8","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"24.2","Brain RNA - basal ganglia [nTPM]":"33.6","Brain RNA - cerebellum [nTPM]":"30.1","Brain RNA - cerebral cortex [nTPM]":"39.3","Brain RNA - hippocampal formation [nTPM]":"29.2","Brain RNA - hypothalamus [nTPM]":"25.3","Brain RNA - medulla oblongata [nTPM]":"40.7","Brain RNA - midbrain [nTPM]":"28.0","Brain RNA - pons [nTPM]":"37.4","Brain RNA - spinal cord [nTPM]":"34.8","Brain RNA - thalamus [nTPM]":"28.8","Brain RNA - white matter [nTPM]":"56.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"97.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"3.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"1721.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"636.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"47.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"15.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2869.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"NLGN1","Gene synonym":["KIAA1070"],"Ensembl":"ENSG00000169760","Gene description":"Neuroligin 1","Uniprot":["Q8N2Q7"],"Chromosome":"3","Position":"173396284-174286644","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Biological rhythms","Cell adhesion"],"Molecular function":null,"Disease involvement":["Autism","Autism spectrum disorder","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"31.0","retina":"13.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"31","RNA single cell type specific nTPM":{"Excitatory neurons":"1484.7","Inhibitory neurons":"1700.0","Oligodendrocyte precursor cells":"4004.1","Oligodendrocytes":"1261.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"glioma":"3.8","melanoma":"2.2","renal cancer":"3.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"fHDF\/TERT166":"25.9","HUVEC TERT2":"24.9","RH-30":"26.2","WM-115":"27.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006572","HPA006680","CAB033261"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nuclear bodies","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"82000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"CAB033261":"AB_2151659","HPA006572":null,"HPA006680":"AB_1854400"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.0","Tissue RNA - adrenal gland [nTPM]":"1.0","Tissue RNA - amygdala [nTPM]":"12.6","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"10.8","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.7","Tissue RNA - cerebellum [nTPM]":"31.0","Tissue RNA - cerebral cortex [nTPM]":"12.1","Tissue RNA - cervix [nTPM]":"3.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"2.0","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"2.1","Tissue RNA - epididymis [nTPM]":"2.5","Tissue RNA - esophagus [nTPM]":"2.5","Tissue RNA - fallopian tube [nTPM]":"3.0","Tissue RNA - gallbladder [nTPM]":"1.6","Tissue RNA - heart muscle [nTPM]":"3.2","Tissue RNA - hippocampal formation [nTPM]":"12.5","Tissue RNA - hypothalamus [nTPM]":"15.2","Tissue RNA - kidney [nTPM]":"2.9","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"5.3","Tissue RNA - midbrain [nTPM]":"5.4","Tissue RNA - ovary [nTPM]":"1.3","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"1.8","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"4.0","Tissue RNA - prostate [nTPM]":"2.2","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"13.8","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"3.0","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.6","Tissue RNA - smooth muscle [nTPM]":"2.7","Tissue RNA - spinal cord [nTPM]":"4.4","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.8","Tissue RNA - testis [nTPM]":"7.0","Tissue RNA - thalamus [nTPM]":"20.5","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.9","Tissue RNA - tongue [nTPM]":"1.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"2.9","Tissue RNA - vagina [nTPM]":"1.3","Tissue RNA - white matter [nTPM]":"7.2","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"6.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"11.8","Cell RNA - ASC TERT1 [nTPM]":"12.4","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"5.2","Cell RNA - BJ hTERT+ [nTPM]":"12.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.8","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.5","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"25.9","Cell RNA - GAMG [nTPM]":"4.7","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"3.7","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"1.3","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"6.0","Cell RNA - HEL [nTPM]":"1.7","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"9.7","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"10.0","Cell RNA - HUVEC TERT2 [nTPM]":"24.9","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"1.7","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"7.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"1.7","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"26.2","Cell RNA - RPMI-8226 [nTPM]":"6.4","Cell RNA - RPTEC TERT1 [nTPM]":"4.7","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"2.5","Cell RNA - SH-SY5Y [nTPM]":"1.7","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"12.3","Cell RNA - SuSa [nTPM]":"1.1","Cell RNA - T-47d [nTPM]":"0.6","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"3.1","Cell RNA - U-138 MG [nTPM]":"13.5","Cell RNA - U-2 OS [nTPM]":"1.3","Cell RNA - U-2197 [nTPM]":"9.9","Cell RNA - U-251 MG [nTPM]":"11.6","Cell RNA - U-266\/70 [nTPM]":"11.7","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"4.6","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"27.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"12.6","Brain RNA - basal ganglia [nTPM]":"10.8","Brain RNA - cerebellum [nTPM]":"31.0","Brain RNA - cerebral cortex [nTPM]":"12.1","Brain RNA - hippocampal formation [nTPM]":"12.5","Brain RNA - hypothalamus [nTPM]":"15.2","Brain RNA - medulla oblongata [nTPM]":"5.3","Brain RNA - midbrain [nTPM]":"5.4","Brain RNA - pons [nTPM]":"4.0","Brain RNA - spinal cord [nTPM]":"4.4","Brain RNA - thalamus [nTPM]":"20.5","Brain RNA - white matter [nTPM]":"7.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"66.6","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"14.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"55.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1484.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"8.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1700.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"12.5","Single Cell Type RNA - Leydig cells [nTPM]":"25.7","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"60.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"24.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4004.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1261.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"14.3","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"1.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"1.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"NLGN4X","Gene synonym":["HLNX","KIAA1260","NLGN","NLGN4"],"Ensembl":"ENSG00000146938","Gene description":"Neuroligin 4 X-linked","Uniprot":["Q8N0W4"],"Chromosome":"X","Position":"5840637-6228867","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Asperger syndrome","Autism","Autism spectrum disorder"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"28.5","lymphoid tissue":"14.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"113.9","Excitatory neurons":"162.2","Inhibitory neurons":"236.8","Oligodendrocyte precursor cells":"702.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"endometrial cancer":"2.7","glioma":"8.5","testis cancer":"3.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"AF22":"55.6","NTERA-2":"44.1","SuSa":"42.7"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001651"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA001651":"AB_1079470"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.4","Tissue RNA - adrenal gland [nTPM]":"1.3","Tissue RNA - amygdala [nTPM]":"8.8","Tissue RNA - appendix [nTPM]":"1.8","Tissue RNA - basal ganglia [nTPM]":"10.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"2.2","Tissue RNA - cerebellum [nTPM]":"9.8","Tissue RNA - cerebral cortex [nTPM]":"12.7","Tissue RNA - cervix [nTPM]":"5.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"3.4","Tissue RNA - duodenum [nTPM]":"1.3","Tissue RNA - endometrium 1 [nTPM]":"2.3","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"0.7","Tissue RNA - fallopian tube [nTPM]":"2.0","Tissue RNA - gallbladder [nTPM]":"2.5","Tissue RNA - heart muscle [nTPM]":"4.5","Tissue RNA - hippocampal formation [nTPM]":"14.8","Tissue RNA - hypothalamus [nTPM]":"28.5","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"1.3","Tissue RNA - lung [nTPM]":"1.1","Tissue RNA - lymph node [nTPM]":"0.8","Tissue RNA - medulla oblongata [nTPM]":"6.5","Tissue RNA - midbrain [nTPM]":"5.6","Tissue RNA - ovary [nTPM]":"11.6","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"5.2","Tissue RNA - pituitary gland [nTPM]":"1.7","Tissue RNA - placenta [nTPM]":"3.6","Tissue RNA - pons [nTPM]":"4.4","Tissue RNA - prostate [nTPM]":"1.1","Tissue RNA - rectum [nTPM]":"1.9","Tissue RNA - retina [nTPM]":"9.2","Tissue RNA - salivary gland [nTPM]":"0.8","Tissue RNA - seminal vesicle [nTPM]":"1.9","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"2.6","Tissue RNA - smooth muscle [nTPM]":"3.7","Tissue RNA - spinal cord [nTPM]":"1.6","Tissue RNA - spleen [nTPM]":"2.2","Tissue RNA - stomach 1 [nTPM]":"1.1","Tissue RNA - testis [nTPM]":"2.6","Tissue RNA - thalamus [nTPM]":"8.9","Tissue RNA - thymus [nTPM]":"14.3","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"2.1","Tissue RNA - vagina [nTPM]":"1.4","Tissue RNA - white matter [nTPM]":"4.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"55.6","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"1.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"1.9","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"8.7","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"7.4","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"44.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"4.1","Cell RNA - RT4 [nTPM]":"11.5","Cell RNA - SCLC-21H [nTPM]":"2.7","Cell RNA - SH-SY5Y [nTPM]":"3.5","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"42.7","Cell RNA - T-47d [nTPM]":"5.7","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"3.6","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"10.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"8.8","Brain RNA - basal ganglia [nTPM]":"10.1","Brain RNA - cerebellum [nTPM]":"9.8","Brain RNA - cerebral cortex [nTPM]":"12.7","Brain RNA - hippocampal formation [nTPM]":"14.8","Brain RNA - hypothalamus [nTPM]":"28.5","Brain RNA - medulla oblongata [nTPM]":"6.5","Brain RNA - midbrain [nTPM]":"5.6","Brain RNA - pons [nTPM]":"4.4","Brain RNA - spinal cord [nTPM]":"1.6","Brain RNA - thalamus [nTPM]":"8.9","Brain RNA - white matter [nTPM]":"4.2","Single Cell Type RNA - Adipocytes [nTPM]":"12.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"113.9","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"15.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.7","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"69.5","Single Cell Type RNA - Endothelial cells [nTPM]":"2.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"162.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.4","Single Cell Type RNA - Fibroblasts [nTPM]":"9.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"33.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"236.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"18.0","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"12.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"702.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"68.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"29.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.3","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.0","Single Cell Type RNA - Spermatocytes [nTPM]":"2.0","Single Cell Type RNA - Spermatogonia [nTPM]":"5.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.6","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"8.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"NMNAT1","Gene synonym":["LCA9","NMNAT","PNAT1"],"Ensembl":"ENSG00000173614","Gene description":"Nicotinamide nucleotide adenylyltransferase 1","Uniprot":["Q9HAN9"],"Chromosome":"1","Position":"9943428-9985501","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Pyridine nucleotide biosynthesis"],"Molecular function":["Nucleotidyltransferase","Transferase"],"Disease involvement":["Disease variant","Leber congenital amaurosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059447"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA059447":"AB_2684022"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.54e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.85e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.2","Tissue RNA - adrenal gland [nTPM]":"7.4","Tissue RNA - amygdala [nTPM]":"5.4","Tissue RNA - appendix [nTPM]":"4.4","Tissue RNA - basal ganglia [nTPM]":"6.0","Tissue RNA - bone marrow [nTPM]":"2.5","Tissue RNA - breast [nTPM]":"5.7","Tissue RNA - cerebellum [nTPM]":"4.8","Tissue RNA - cerebral cortex [nTPM]":"7.7","Tissue RNA - cervix [nTPM]":"5.4","Tissue RNA - choroid plexus [nTPM]":"9.2","Tissue RNA - colon [nTPM]":"9.0","Tissue RNA - duodenum [nTPM]":"6.0","Tissue RNA - endometrium 1 [nTPM]":"3.8","Tissue RNA - epididymis [nTPM]":"5.8","Tissue RNA - esophagus [nTPM]":"5.2","Tissue RNA - fallopian tube [nTPM]":"4.8","Tissue RNA - gallbladder [nTPM]":"3.4","Tissue RNA - heart muscle [nTPM]":"10.7","Tissue RNA - hippocampal formation [nTPM]":"5.1","Tissue RNA - hypothalamus [nTPM]":"5.2","Tissue RNA - kidney [nTPM]":"8.2","Tissue RNA - liver [nTPM]":"7.8","Tissue RNA - lung [nTPM]":"3.2","Tissue RNA - lymph node [nTPM]":"4.3","Tissue RNA - medulla oblongata [nTPM]":"5.6","Tissue RNA - midbrain [nTPM]":"5.4","Tissue RNA - ovary [nTPM]":"2.9","Tissue RNA - pancreas [nTPM]":"4.9","Tissue RNA - parathyroid gland [nTPM]":"8.2","Tissue RNA - pituitary gland [nTPM]":"3.8","Tissue RNA - placenta [nTPM]":"3.7","Tissue RNA - pons [nTPM]":"5.5","Tissue RNA - prostate [nTPM]":"4.5","Tissue RNA - rectum [nTPM]":"9.0","Tissue RNA - retina [nTPM]":"5.3","Tissue RNA - salivary gland [nTPM]":"5.2","Tissue RNA - seminal vesicle [nTPM]":"5.4","Tissue RNA - skeletal muscle [nTPM]":"23.3","Tissue RNA - skin 1 [nTPM]":"5.7","Tissue RNA - small intestine [nTPM]":"6.1","Tissue RNA - smooth muscle [nTPM]":"5.0","Tissue RNA - spinal cord [nTPM]":"4.7","Tissue RNA - spleen [nTPM]":"5.0","Tissue RNA - stomach 1 [nTPM]":"4.4","Tissue RNA - testis [nTPM]":"4.3","Tissue RNA - thalamus [nTPM]":"5.9","Tissue RNA - thymus [nTPM]":"4.2","Tissue RNA - thyroid gland [nTPM]":"7.3","Tissue RNA - tongue [nTPM]":"16.9","Tissue RNA - tonsil [nTPM]":"4.6","Tissue RNA - urinary bladder [nTPM]":"4.0","Tissue RNA - vagina [nTPM]":"3.6","Tissue RNA - white matter [nTPM]":"7.2","Cell RNA - A-431 [nTPM]":"4.6","Cell RNA - A549 [nTPM]":"5.4","Cell RNA - AF22 [nTPM]":"7.5","Cell RNA - AN3-CA [nTPM]":"7.1","Cell RNA - ASC diff [nTPM]":"13.4","Cell RNA - ASC TERT1 [nTPM]":"12.2","Cell RNA - BEWO [nTPM]":"1.8","Cell RNA - BJ [nTPM]":"9.1","Cell RNA - BJ hTERT+ [nTPM]":"7.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.7","Cell RNA - CACO-2 [nTPM]":"2.4","Cell RNA - CAPAN-2 [nTPM]":"7.7","Cell RNA - Daudi [nTPM]":"4.8","Cell RNA - EFO-21 [nTPM]":"5.7","Cell RNA - fHDF\/TERT166 [nTPM]":"12.9","Cell RNA - GAMG [nTPM]":"4.5","Cell RNA - HaCaT [nTPM]":"4.6","Cell RNA - HAP1 [nTPM]":"9.4","Cell RNA - HBEC3-KT [nTPM]":"12.4","Cell RNA - HBF TERT88 [nTPM]":"11.0","Cell RNA - HDLM-2 [nTPM]":"10.4","Cell RNA - HEK 293 [nTPM]":"4.8","Cell RNA - HEL [nTPM]":"7.6","Cell RNA - HeLa [nTPM]":"3.0","Cell RNA - Hep G2 [nTPM]":"7.6","Cell RNA - HHSteC [nTPM]":"11.4","Cell RNA - HL-60 [nTPM]":"6.7","Cell RNA - HMC-1 [nTPM]":"7.7","Cell RNA - HSkMC [nTPM]":"13.3","Cell RNA - hTCEpi [nTPM]":"14.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.1","Cell RNA - hTERT-HME1 [nTPM]":"17.4","Cell RNA - hTERT-RPE1 [nTPM]":"9.5","Cell RNA - HUVEC TERT2 [nTPM]":"10.2","Cell RNA - JURKAT [nTPM]":"10.4","Cell RNA - K-562 [nTPM]":"9.7","Cell RNA - Karpas-707 [nTPM]":"3.1","Cell RNA - LHCN-M2 [nTPM]":"10.9","Cell RNA - MCF7 [nTPM]":"8.0","Cell RNA - MOLT-4 [nTPM]":"3.8","Cell RNA - NB-4 [nTPM]":"4.4","Cell RNA - NTERA-2 [nTPM]":"0.9","Cell RNA - OE19 [nTPM]":"10.2","Cell RNA - PC-3 [nTPM]":"10.2","Cell RNA - REH [nTPM]":"4.2","Cell RNA - RH-30 [nTPM]":"4.7","Cell RNA - RPMI-8226 [nTPM]":"2.7","Cell RNA - RPTEC TERT1 [nTPM]":"11.9","Cell RNA - RT4 [nTPM]":"2.5","Cell RNA - SCLC-21H [nTPM]":"5.4","Cell RNA - SH-SY5Y [nTPM]":"2.8","Cell RNA - SiHa [nTPM]":"11.8","Cell RNA - SK-BR-3 [nTPM]":"9.7","Cell RNA - SK-MEL-30 [nTPM]":"10.4","Cell RNA - SuSa [nTPM]":"3.8","Cell RNA - T-47d [nTPM]":"3.5","Cell RNA - THP-1 [nTPM]":"7.2","Cell RNA - TIME [nTPM]":"10.2","Cell RNA - U-138 MG [nTPM]":"4.1","Cell RNA - U-2 OS [nTPM]":"3.3","Cell RNA - U-2197 [nTPM]":"8.7","Cell RNA - U-251 MG [nTPM]":"4.2","Cell RNA - U-266\/70 [nTPM]":"4.5","Cell RNA - U-266\/84 [nTPM]":"4.3","Cell RNA - U-698 [nTPM]":"4.5","Cell RNA - U-87 MG [nTPM]":"7.1","Cell RNA - U-937 [nTPM]":"13.8","Cell RNA - WM-115 [nTPM]":"8.6","Blood RNA - basophil [nTPM]":"7.5","Blood RNA - classical monocyte [nTPM]":"3.7","Blood RNA - eosinophil [nTPM]":"3.2","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"2.6","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"4.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.6","Blood RNA - memory CD8 T-cell [nTPM]":"1.9","Blood RNA - myeloid DC [nTPM]":"3.3","Blood RNA - naive B-cell [nTPM]":"2.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.4","Blood RNA - naive CD8 T-cell [nTPM]":"1.8","Blood RNA - neutrophil [nTPM]":"9.1","Blood RNA - NK-cell [nTPM]":"2.5","Blood RNA - non-classical monocyte [nTPM]":"3.9","Blood RNA - plasmacytoid DC [nTPM]":"3.2","Blood RNA - T-reg [nTPM]":"1.5","Blood RNA - total PBMC [nTPM]":"1.8","Brain RNA - amygdala [nTPM]":"5.4","Brain RNA - basal ganglia [nTPM]":"6.0","Brain RNA - cerebellum [nTPM]":"4.8","Brain RNA - cerebral cortex [nTPM]":"7.7","Brain RNA - hippocampal formation [nTPM]":"5.1","Brain RNA - hypothalamus [nTPM]":"5.2","Brain RNA - medulla oblongata [nTPM]":"5.6","Brain RNA - midbrain [nTPM]":"5.4","Brain RNA - pons [nTPM]":"5.5","Brain RNA - spinal cord [nTPM]":"4.7","Brain RNA - thalamus [nTPM]":"5.9","Brain RNA - white matter [nTPM]":"7.2","Single Cell Type RNA - Adipocytes [nTPM]":"5.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.4","Single Cell Type RNA - Astrocytes [nTPM]":"10.1","Single Cell Type RNA - B-cells [nTPM]":"3.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"7.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"7.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.1","Single Cell Type RNA - dendritic cells [nTPM]":"3.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"9.1","Single Cell Type RNA - Early spermatids [nTPM]":"7.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.1","Single Cell Type RNA - Endothelial cells [nTPM]":"7.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.7","Single Cell Type RNA - Fibroblasts [nTPM]":"5.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.1","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"9.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"9.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.9","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.6","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"10.3","Single Cell Type RNA - Langerhans cells [nTPM]":"2.7","Single Cell Type RNA - Late spermatids [nTPM]":"3.7","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"7.2","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"13.5","Single Cell Type RNA - Muller glia cells [nTPM]":"9.6","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"13.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.0","Single Cell Type RNA - Paneth cells [nTPM]":"6.2","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"19.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.1","Single Cell Type RNA - Spermatocytes [nTPM]":"17.3","Single Cell Type RNA - Spermatogonia [nTPM]":"8.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.0","Single Cell Type RNA - T-cells [nTPM]":"3.6","Single Cell Type RNA - Theca cells [nTPM]":"13.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.5","Single Cell Type RNA - Urothelial cells [nTPM]":"4.8"},{"Gene":"NOTCH1","Gene synonym":["TAN1"],"Ensembl":"ENSG00000148400","Gene description":"Notch receptor 1","Uniprot":["P46531"],"Chromosome":"9","Position":"136494433-136546048","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Angiogenesis","Differentiation","Notch signaling pathway","Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"56.2","Astrocytes":"67.3","Hepatic stellate cells":"68.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"2.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"47.0","HDLM-2":"32.3","HMC-1":"39.7","MOLT-4":"72.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB008112","CAB022466","HPA067168"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"29000000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB008112":"AB_2153490","CAB022466":null,"HPA067168":"AB_2685795"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.45e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-2"},"Tissue RNA - adipose tissue [nTPM]":"18.2","Tissue RNA - adrenal gland [nTPM]":"4.2","Tissue RNA - amygdala [nTPM]":"10.4","Tissue RNA - appendix [nTPM]":"4.9","Tissue RNA - basal ganglia [nTPM]":"16.1","Tissue RNA - bone marrow [nTPM]":"4.3","Tissue RNA - breast [nTPM]":"15.0","Tissue RNA - cerebellum [nTPM]":"12.1","Tissue RNA - cerebral cortex [nTPM]":"9.3","Tissue RNA - cervix [nTPM]":"14.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"19.8","Tissue RNA - duodenum [nTPM]":"4.3","Tissue RNA - endometrium 1 [nTPM]":"12.7","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"16.3","Tissue RNA - fallopian tube [nTPM]":"11.9","Tissue RNA - gallbladder [nTPM]":"0.9","Tissue RNA - heart muscle [nTPM]":"14.9","Tissue RNA - hippocampal formation [nTPM]":"8.6","Tissue RNA - hypothalamus [nTPM]":"5.5","Tissue RNA - kidney [nTPM]":"11.8","Tissue RNA - liver [nTPM]":"9.2","Tissue RNA - lung [nTPM]":"22.2","Tissue RNA - lymph node [nTPM]":"3.0","Tissue RNA - medulla oblongata [nTPM]":"13.5","Tissue RNA - midbrain [nTPM]":"12.3","Tissue RNA - ovary [nTPM]":"5.1","Tissue RNA - pancreas [nTPM]":"14.0","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"6.3","Tissue RNA - placenta [nTPM]":"2.6","Tissue RNA - pons [nTPM]":"9.8","Tissue RNA - prostate [nTPM]":"15.4","Tissue RNA - rectum [nTPM]":"0.6","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"10.7","Tissue RNA - seminal vesicle [nTPM]":"3.1","Tissue RNA - skeletal muscle [nTPM]":"5.0","Tissue RNA - skin 1 [nTPM]":"24.2","Tissue RNA - small intestine [nTPM]":"14.2","Tissue RNA - smooth muscle [nTPM]":"1.3","Tissue RNA - spinal cord [nTPM]":"9.7","Tissue RNA - spleen [nTPM]":"24.8","Tissue RNA - stomach 1 [nTPM]":"10.0","Tissue RNA - testis [nTPM]":"2.5","Tissue RNA - thalamus [nTPM]":"13.9","Tissue RNA - thymus [nTPM]":"4.0","Tissue RNA - thyroid gland [nTPM]":"11.2","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"0.9","Tissue RNA - urinary bladder [nTPM]":"14.2","Tissue RNA - vagina [nTPM]":"16.5","Tissue RNA - white matter [nTPM]":"14.0","Cell RNA - A-431 [nTPM]":"8.8","Cell RNA - A549 [nTPM]":"10.6","Cell RNA - AF22 [nTPM]":"4.0","Cell RNA - AN3-CA [nTPM]":"2.6","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"17.7","Cell RNA - BJ [nTPM]":"3.3","Cell RNA - BJ hTERT+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"1.8","Cell RNA - CAPAN-2 [nTPM]":"0.9","Cell RNA - Daudi [nTPM]":"13.3","Cell RNA - EFO-21 [nTPM]":"10.3","Cell RNA - fHDF\/TERT166 [nTPM]":"1.3","Cell RNA - GAMG [nTPM]":"1.6","Cell RNA - HaCaT [nTPM]":"47.0","Cell RNA - HAP1 [nTPM]":"1.0","Cell RNA - HBEC3-KT [nTPM]":"8.6","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"32.3","Cell RNA - HEK 293 [nTPM]":"2.0","Cell RNA - HEL [nTPM]":"5.5","Cell RNA - HeLa [nTPM]":"6.1","Cell RNA - Hep G2 [nTPM]":"0.6","Cell RNA - HHSteC [nTPM]":"2.1","Cell RNA - HL-60 [nTPM]":"6.9","Cell RNA - HMC-1 [nTPM]":"39.7","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"16.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.4","Cell RNA - hTERT-HME1 [nTPM]":"1.9","Cell RNA - hTERT-RPE1 [nTPM]":"0.7","Cell RNA - HUVEC TERT2 [nTPM]":"9.0","Cell RNA - JURKAT [nTPM]":"3.7","Cell RNA - K-562 [nTPM]":"3.6","Cell RNA - Karpas-707 [nTPM]":"1.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"9.0","Cell RNA - MOLT-4 [nTPM]":"72.3","Cell RNA - NB-4 [nTPM]":"13.1","Cell RNA - NTERA-2 [nTPM]":"8.4","Cell RNA - OE19 [nTPM]":"2.9","Cell RNA - PC-3 [nTPM]":"7.7","Cell RNA - REH [nTPM]":"15.7","Cell RNA - RH-30 [nTPM]":"9.2","Cell RNA - RPMI-8226 [nTPM]":"19.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.6","Cell RNA - RT4 [nTPM]":"4.2","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.7","Cell RNA - SiHa [nTPM]":"6.1","Cell RNA - SK-BR-3 [nTPM]":"4.3","Cell RNA - SK-MEL-30 [nTPM]":"3.4","Cell RNA - SuSa [nTPM]":"1.0","Cell RNA - T-47d [nTPM]":"3.2","Cell RNA - THP-1 [nTPM]":"10.4","Cell RNA - TIME [nTPM]":"22.7","Cell RNA - U-138 MG [nTPM]":"5.0","Cell RNA - U-2 OS [nTPM]":"9.3","Cell RNA - U-2197 [nTPM]":"5.9","Cell RNA - U-251 MG [nTPM]":"4.3","Cell RNA - U-266\/70 [nTPM]":"2.4","Cell RNA - U-266\/84 [nTPM]":"2.6","Cell RNA - U-698 [nTPM]":"4.1","Cell RNA - U-87 MG [nTPM]":"3.7","Cell RNA - U-937 [nTPM]":"5.0","Cell RNA - WM-115 [nTPM]":"26.1","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"2.3","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"10.4","Brain RNA - basal ganglia [nTPM]":"16.1","Brain RNA - cerebellum [nTPM]":"12.1","Brain RNA - cerebral cortex [nTPM]":"9.3","Brain RNA - hippocampal formation [nTPM]":"8.6","Brain RNA - hypothalamus [nTPM]":"5.5","Brain RNA - medulla oblongata [nTPM]":"13.5","Brain RNA - midbrain [nTPM]":"12.3","Brain RNA - pons [nTPM]":"9.8","Brain RNA - spinal cord [nTPM]":"9.7","Brain RNA - thalamus [nTPM]":"13.9","Brain RNA - white matter [nTPM]":"14.0","Single Cell Type RNA - Adipocytes [nTPM]":"56.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.9","Single Cell Type RNA - Astrocytes [nTPM]":"67.3","Single Cell Type RNA - B-cells [nTPM]":"8.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"24.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"35.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.9","Single Cell Type RNA - Bipolar cells [nTPM]":"0.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"16.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - dendritic cells [nTPM]":"14.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.9","Single Cell Type RNA - Endothelial cells [nTPM]":"53.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.2","Single Cell Type RNA - Fibroblasts [nTPM]":"6.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.3","Single Cell Type RNA - granulocytes [nTPM]":"34.9","Single Cell Type RNA - Granulosa cells [nTPM]":"1.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"68.2","Single Cell Type RNA - Hepatocytes [nTPM]":"7.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.3","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.8","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"10.1","Single Cell Type RNA - Langerhans cells [nTPM]":"17.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"15.2","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"14.3","Single Cell Type RNA - Muller glia cells [nTPM]":"46.6","Single Cell Type RNA - NK-cells [nTPM]":"24.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"33.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.1","Single Cell Type RNA - Paneth cells [nTPM]":"11.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"5.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"3.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"29.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - T-cells [nTPM]":"15.0","Single Cell Type RNA - Theca cells [nTPM]":"1.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"28.8","Single Cell Type RNA - Urothelial cells [nTPM]":"15.6"},{"Gene":"NOX1","Gene synonym":["GP91-2","MOX1","NOH-1","NOH1"],"Ensembl":"ENSG00000007952","Gene description":"NADPH oxidase 1","Uniprot":["Q9Y5S8"],"Chromosome":"X","Position":"100843324-100874359","Protein class":["Disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Electron transport","Ion transport","Transport"],"Molecular function":["Ion channel","Oxidoreductase","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"24","RNA tissue specific nTPM":{"intestine":"71.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Distal enterocytes":"45.8","Intestinal goblet cells":"21.4","Paneth cells":"29.1","Undifferentiated cells":"64.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"18","RNA cancer specific FPKM":{"colorectal cancer":"82.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"15","RNA cell line specific nTPM":{"CACO-2":"30.9","OE19":"11.6"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.71e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"2.9","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"58.9","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.5","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.7","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"71.7","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"2.4","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"1.6","Tissue RNA - smooth muscle [nTPM]":"1.6","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"1.3","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"1.1","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"30.9","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"0.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.7","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"1.4","Cell RNA - HEL [nTPM]":"0.5","Cell RNA - HeLa [nTPM]":"0.6","Cell RNA - Hep G2 [nTPM]":"0.9","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.7","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.6","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"1.3","Cell RNA - NB-4 [nTPM]":"1.2","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"11.6","Cell RNA - PC-3 [nTPM]":"1.1","Cell RNA - REH [nTPM]":"0.7","Cell RNA - RH-30 [nTPM]":"0.7","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"1.1","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.6","Cell RNA - SiHa [nTPM]":"0.7","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.7","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"1.0","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.4","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.8","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.7","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"0.8","Cell RNA - U-937 [nTPM]":"1.4","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"45.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.9","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"29.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"64.8","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"NPC1","Gene synonym":["SLC65A1"],"Ensembl":"ENSG00000141458","Gene description":"NPC intracellular cholesterol transporter 1","Uniprot":["O15118"],"Chromosome":"18","Position":"23506184-23586506","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Cholesterol metabolism","Host-virus interaction","Lipid metabolism","Lipid transport","Steroid metabolism","Sterol metabolism","Transport"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Disease variant","Niemann-Pick disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"110.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"182.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"70.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTERT-HME1":"273.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026618","CAB070132","HPA077445"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB070132":"AB_10001101","HPA026618":"AB_1854580","HPA077445":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.26e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-3"},"Tissue RNA - adipose tissue [nTPM]":"17.5","Tissue RNA - adrenal gland [nTPM]":"76.7","Tissue RNA - amygdala [nTPM]":"35.1","Tissue RNA - appendix [nTPM]":"16.9","Tissue RNA - basal ganglia [nTPM]":"69.6","Tissue RNA - bone marrow [nTPM]":"42.6","Tissue RNA - breast [nTPM]":"20.0","Tissue RNA - cerebellum [nTPM]":"55.3","Tissue RNA - cerebral cortex [nTPM]":"47.8","Tissue RNA - cervix [nTPM]":"16.7","Tissue RNA - choroid plexus [nTPM]":"28.6","Tissue RNA - colon [nTPM]":"13.7","Tissue RNA - duodenum [nTPM]":"14.5","Tissue RNA - endometrium 1 [nTPM]":"16.7","Tissue RNA - epididymis [nTPM]":"15.0","Tissue RNA - esophagus [nTPM]":"20.5","Tissue RNA - fallopian tube [nTPM]":"13.4","Tissue RNA - gallbladder [nTPM]":"15.3","Tissue RNA - heart muscle [nTPM]":"11.5","Tissue RNA - hippocampal formation [nTPM]":"41.1","Tissue RNA - hypothalamus [nTPM]":"44.3","Tissue RNA - kidney [nTPM]":"16.8","Tissue RNA - liver [nTPM]":"15.2","Tissue RNA - lung [nTPM]":"29.0","Tissue RNA - lymph node [nTPM]":"20.4","Tissue RNA - medulla oblongata [nTPM]":"73.3","Tissue RNA - midbrain [nTPM]":"55.8","Tissue RNA - ovary [nTPM]":"16.0","Tissue RNA - pancreas [nTPM]":"11.9","Tissue RNA - parathyroid gland [nTPM]":"72.6","Tissue RNA - pituitary gland [nTPM]":"15.0","Tissue RNA - placenta [nTPM]":"27.8","Tissue RNA - pons [nTPM]":"66.6","Tissue RNA - prostate [nTPM]":"13.1","Tissue RNA - rectum [nTPM]":"12.0","Tissue RNA - retina [nTPM]":"28.0","Tissue RNA - salivary gland [nTPM]":"36.8","Tissue RNA - seminal vesicle [nTPM]":"13.2","Tissue RNA - skeletal muscle [nTPM]":"22.9","Tissue RNA - skin 1 [nTPM]":"24.3","Tissue RNA - small intestine [nTPM]":"17.8","Tissue RNA - smooth muscle [nTPM]":"15.1","Tissue RNA - spinal cord [nTPM]":"49.8","Tissue RNA - spleen [nTPM]":"17.1","Tissue RNA - stomach 1 [nTPM]":"20.4","Tissue RNA - testis [nTPM]":"13.7","Tissue RNA - thalamus [nTPM]":"55.8","Tissue RNA - thymus [nTPM]":"12.2","Tissue RNA - thyroid gland [nTPM]":"11.8","Tissue RNA - tongue [nTPM]":"14.1","Tissue RNA - tonsil [nTPM]":"15.6","Tissue RNA - urinary bladder [nTPM]":"15.8","Tissue RNA - vagina [nTPM]":"18.0","Tissue RNA - white matter [nTPM]":"110.6","Cell RNA - A-431 [nTPM]":"21.5","Cell RNA - A549 [nTPM]":"41.4","Cell RNA - AF22 [nTPM]":"17.8","Cell RNA - AN3-CA [nTPM]":"29.3","Cell RNA - ASC diff [nTPM]":"55.8","Cell RNA - ASC TERT1 [nTPM]":"44.6","Cell RNA - BEWO [nTPM]":"40.7","Cell RNA - BJ [nTPM]":"37.3","Cell RNA - BJ hTERT+ [nTPM]":"81.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"38.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"84.3","Cell RNA - CACO-2 [nTPM]":"28.1","Cell RNA - CAPAN-2 [nTPM]":"30.7","Cell RNA - Daudi [nTPM]":"18.4","Cell RNA - EFO-21 [nTPM]":"28.0","Cell RNA - fHDF\/TERT166 [nTPM]":"55.0","Cell RNA - GAMG [nTPM]":"132.8","Cell RNA - HaCaT [nTPM]":"59.3","Cell RNA - HAP1 [nTPM]":"22.6","Cell RNA - HBEC3-KT [nTPM]":"63.2","Cell RNA - HBF TERT88 [nTPM]":"35.2","Cell RNA - HDLM-2 [nTPM]":"15.0","Cell RNA - HEK 293 [nTPM]":"17.9","Cell RNA - HEL [nTPM]":"6.8","Cell RNA - HeLa [nTPM]":"35.7","Cell RNA - Hep G2 [nTPM]":"63.2","Cell RNA - HHSteC [nTPM]":"79.2","Cell RNA - HL-60 [nTPM]":"25.0","Cell RNA - HMC-1 [nTPM]":"28.5","Cell RNA - HSkMC [nTPM]":"42.2","Cell RNA - hTCEpi [nTPM]":"61.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"81.7","Cell RNA - hTERT-HME1 [nTPM]":"273.2","Cell RNA - hTERT-RPE1 [nTPM]":"76.8","Cell RNA - HUVEC TERT2 [nTPM]":"40.3","Cell RNA - JURKAT [nTPM]":"20.7","Cell RNA - K-562 [nTPM]":"20.1","Cell RNA - Karpas-707 [nTPM]":"47.5","Cell RNA - LHCN-M2 [nTPM]":"44.2","Cell RNA - MCF7 [nTPM]":"32.4","Cell RNA - MOLT-4 [nTPM]":"10.6","Cell RNA - NB-4 [nTPM]":"14.9","Cell RNA - NTERA-2 [nTPM]":"12.5","Cell RNA - OE19 [nTPM]":"24.4","Cell RNA - PC-3 [nTPM]":"37.3","Cell RNA - REH [nTPM]":"15.3","Cell RNA - RH-30 [nTPM]":"28.1","Cell RNA - RPMI-8226 [nTPM]":"45.0","Cell RNA - RPTEC TERT1 [nTPM]":"88.8","Cell RNA - RT4 [nTPM]":"51.9","Cell RNA - SCLC-21H [nTPM]":"7.5","Cell RNA - SH-SY5Y [nTPM]":"14.5","Cell RNA - SiHa [nTPM]":"44.6","Cell RNA - SK-BR-3 [nTPM]":"62.0","Cell RNA - SK-MEL-30 [nTPM]":"54.3","Cell RNA - SuSa [nTPM]":"27.7","Cell RNA - T-47d [nTPM]":"15.9","Cell RNA - THP-1 [nTPM]":"19.5","Cell RNA - TIME [nTPM]":"50.0","Cell RNA - U-138 MG [nTPM]":"81.1","Cell RNA - U-2 OS [nTPM]":"15.3","Cell RNA - U-2197 [nTPM]":"32.4","Cell RNA - U-251 MG [nTPM]":"32.3","Cell RNA - U-266\/70 [nTPM]":"29.7","Cell RNA - U-266\/84 [nTPM]":"97.1","Cell RNA - U-698 [nTPM]":"12.2","Cell RNA - U-87 MG [nTPM]":"177.7","Cell RNA - U-937 [nTPM]":"21.8","Cell RNA - WM-115 [nTPM]":"37.1","Blood RNA - basophil [nTPM]":"4.4","Blood RNA - classical monocyte [nTPM]":"9.0","Blood RNA - eosinophil [nTPM]":"8.8","Blood RNA - gdT-cell [nTPM]":"29.7","Blood RNA - intermediate monocyte [nTPM]":"8.7","Blood RNA - MAIT T-cell [nTPM]":"20.5","Blood RNA - memory B-cell [nTPM]":"5.0","Blood RNA - memory CD4 T-cell [nTPM]":"12.4","Blood RNA - memory CD8 T-cell [nTPM]":"20.7","Blood RNA - myeloid DC [nTPM]":"4.0","Blood RNA - naive B-cell [nTPM]":"6.7","Blood RNA - naive CD4 T-cell [nTPM]":"5.5","Blood RNA - naive CD8 T-cell [nTPM]":"15.0","Blood RNA - neutrophil [nTPM]":"7.9","Blood RNA - NK-cell [nTPM]":"10.5","Blood RNA - non-classical monocyte [nTPM]":"13.8","Blood RNA - plasmacytoid DC [nTPM]":"70.9","Blood RNA - T-reg [nTPM]":"17.4","Blood RNA - total PBMC [nTPM]":"10.6","Brain RNA - amygdala [nTPM]":"35.1","Brain RNA - basal ganglia [nTPM]":"69.6","Brain RNA - cerebellum [nTPM]":"55.3","Brain RNA - cerebral cortex [nTPM]":"47.8","Brain RNA - hippocampal formation [nTPM]":"41.1","Brain RNA - hypothalamus [nTPM]":"44.3","Brain RNA - medulla oblongata [nTPM]":"73.3","Brain RNA - midbrain [nTPM]":"55.8","Brain RNA - pons [nTPM]":"66.6","Brain RNA - spinal cord [nTPM]":"49.8","Brain RNA - thalamus [nTPM]":"55.8","Brain RNA - white matter [nTPM]":"110.6","Single Cell Type RNA - Adipocytes [nTPM]":"18.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"56.1","Single Cell Type RNA - Astrocytes [nTPM]":"32.7","Single Cell Type RNA - B-cells [nTPM]":"9.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"34.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"6.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"21.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.1","Single Cell Type RNA - dendritic cells [nTPM]":"61.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"11.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.2","Single Cell Type RNA - Endothelial cells [nTPM]":"16.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"2.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.8","Single Cell Type RNA - Fibroblasts [nTPM]":"13.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"53.9","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"31.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"9.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.9","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.3","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"11.9","Single Cell Type RNA - Langerhans cells [nTPM]":"6.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"9.0","Single Cell Type RNA - Macrophages [nTPM]":"21.0","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"59.0","Single Cell Type RNA - monocytes [nTPM]":"7.2","Single Cell Type RNA - Muller glia cells [nTPM]":"15.1","Single Cell Type RNA - NK-cells [nTPM]":"25.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"39.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"182.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"34.4","Single Cell Type RNA - Paneth cells [nTPM]":"22.6","Single Cell Type RNA - Peritubular cells [nTPM]":"10.5","Single Cell Type RNA - Plasma cells [nTPM]":"15.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"41.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.4","Single Cell Type RNA - Spermatocytes [nTPM]":"13.9","Single Cell Type RNA - Spermatogonia [nTPM]":"25.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.8","Single Cell Type RNA - T-cells [nTPM]":"19.1","Single Cell Type RNA - Theca cells [nTPM]":"52.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.6","Single Cell Type RNA - Urothelial cells [nTPM]":"64.0"},{"Gene":"NPC2","Gene synonym":["EDDM1","HE1","NP-C2"],"Ensembl":"ENSG00000119655","Gene description":"NPC intracellular cholesterol transporter 2","Uniprot":["P61916"],"Chromosome":"14","Position":"74476192-74494177","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins","Transporters"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Lipid transport","Steroid metabolism","Sterol metabolism","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Niemann-Pick disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"21","RNA tissue specific nTPM":{"epididymis":"16783.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"2034.2","Hofbauer cells":"2898.5","Kupffer cells":"2035.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"thyroid cancer":"769.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"668.7","classical monocyte":"1300.7","intermediate monocyte":"1772.7","myeloid DC":"587.8","neutrophil":"674.2","non-classical monocyte":"1252.1","plasmacytoid DC":"2113.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"2113.2","granulocytes":"674.2","monocytes":"1772.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"1619.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000835","CAB032888"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"53000000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 30: Epididymis - Antimicrobial activity","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB032888":"AB_2157036","HPA000835":"AB_1079499"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.83e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.13e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.66e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.55e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Tissue RNA - adipose tissue [nTPM]":"260.1","Tissue RNA - adrenal gland [nTPM]":"297.0","Tissue RNA - amygdala [nTPM]":"127.1","Tissue RNA - appendix [nTPM]":"261.3","Tissue RNA - basal ganglia [nTPM]":"145.4","Tissue RNA - bone marrow [nTPM]":"305.3","Tissue RNA - breast [nTPM]":"221.3","Tissue RNA - cerebellum [nTPM]":"152.2","Tissue RNA - cerebral cortex [nTPM]":"190.6","Tissue RNA - cervix [nTPM]":"284.5","Tissue RNA - choroid plexus [nTPM]":"434.0","Tissue RNA - colon [nTPM]":"259.7","Tissue RNA - duodenum [nTPM]":"201.7","Tissue RNA - endometrium 1 [nTPM]":"196.7","Tissue RNA - epididymis [nTPM]":"16783.1","Tissue RNA - esophagus [nTPM]":"185.0","Tissue RNA - fallopian tube [nTPM]":"170.0","Tissue RNA - gallbladder [nTPM]":"356.0","Tissue RNA - heart muscle [nTPM]":"215.1","Tissue RNA - hippocampal formation [nTPM]":"118.1","Tissue RNA - hypothalamus [nTPM]":"156.9","Tissue RNA - kidney [nTPM]":"322.4","Tissue RNA - liver [nTPM]":"202.4","Tissue RNA - lung [nTPM]":"786.0","Tissue RNA - lymph node [nTPM]":"360.3","Tissue RNA - medulla oblongata [nTPM]":"185.7","Tissue RNA - midbrain [nTPM]":"145.6","Tissue RNA - ovary [nTPM]":"283.1","Tissue RNA - pancreas [nTPM]":"219.9","Tissue RNA - parathyroid gland [nTPM]":"241.3","Tissue RNA - pituitary gland [nTPM]":"197.5","Tissue RNA - placenta [nTPM]":"263.1","Tissue RNA - pons [nTPM]":"179.2","Tissue RNA - prostate [nTPM]":"164.2","Tissue RNA - rectum [nTPM]":"220.8","Tissue RNA - retina [nTPM]":"48.6","Tissue RNA - salivary gland [nTPM]":"221.9","Tissue RNA - seminal vesicle [nTPM]":"261.3","Tissue RNA - skeletal muscle [nTPM]":"58.7","Tissue RNA - skin 1 [nTPM]":"181.6","Tissue RNA - small intestine [nTPM]":"193.3","Tissue RNA - smooth muscle [nTPM]":"180.5","Tissue RNA - spinal cord [nTPM]":"151.1","Tissue RNA - spleen [nTPM]":"305.6","Tissue RNA - stomach 1 [nTPM]":"206.8","Tissue RNA - testis [nTPM]":"156.8","Tissue RNA - thalamus [nTPM]":"172.1","Tissue RNA - thymus [nTPM]":"134.4","Tissue RNA - thyroid gland [nTPM]":"444.7","Tissue RNA - tongue [nTPM]":"114.7","Tissue RNA - tonsil [nTPM]":"241.9","Tissue RNA - urinary bladder [nTPM]":"347.4","Tissue RNA - vagina [nTPM]":"187.9","Tissue RNA - white matter [nTPM]":"195.5","Cell RNA - A-431 [nTPM]":"297.2","Cell RNA - A549 [nTPM]":"199.3","Cell RNA - AF22 [nTPM]":"124.8","Cell RNA - AN3-CA [nTPM]":"179.4","Cell RNA - ASC diff [nTPM]":"1619.3","Cell RNA - ASC TERT1 [nTPM]":"498.6","Cell RNA - BEWO [nTPM]":"404.8","Cell RNA - BJ [nTPM]":"194.1","Cell RNA - BJ hTERT+ [nTPM]":"707.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"200.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"398.9","Cell RNA - CACO-2 [nTPM]":"351.7","Cell RNA - CAPAN-2 [nTPM]":"420.3","Cell RNA - Daudi [nTPM]":"78.6","Cell RNA - EFO-21 [nTPM]":"141.6","Cell RNA - fHDF\/TERT166 [nTPM]":"181.9","Cell RNA - GAMG [nTPM]":"372.6","Cell RNA - HaCaT [nTPM]":"595.9","Cell RNA - HAP1 [nTPM]":"170.0","Cell RNA - HBEC3-KT [nTPM]":"405.5","Cell RNA - HBF TERT88 [nTPM]":"188.6","Cell RNA - HDLM-2 [nTPM]":"120.4","Cell RNA - HEK 293 [nTPM]":"126.3","Cell RNA - HEL [nTPM]":"29.6","Cell RNA - HeLa [nTPM]":"96.7","Cell RNA - Hep G2 [nTPM]":"296.2","Cell RNA - HHSteC [nTPM]":"348.6","Cell RNA - HL-60 [nTPM]":"51.0","Cell RNA - HMC-1 [nTPM]":"548.4","Cell RNA - HSkMC [nTPM]":"467.7","Cell RNA - hTCEpi [nTPM]":"388.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"173.7","Cell RNA - hTERT-HME1 [nTPM]":"336.9","Cell RNA - hTERT-RPE1 [nTPM]":"930.2","Cell RNA - HUVEC TERT2 [nTPM]":"298.1","Cell RNA - JURKAT [nTPM]":"87.0","Cell RNA - K-562 [nTPM]":"32.9","Cell RNA - Karpas-707 [nTPM]":"601.4","Cell RNA - LHCN-M2 [nTPM]":"224.0","Cell RNA - MCF7 [nTPM]":"106.9","Cell RNA - MOLT-4 [nTPM]":"70.1","Cell RNA - NB-4 [nTPM]":"75.9","Cell RNA - NTERA-2 [nTPM]":"52.9","Cell RNA - OE19 [nTPM]":"489.0","Cell RNA - PC-3 [nTPM]":"307.9","Cell RNA - REH [nTPM]":"39.5","Cell RNA - RH-30 [nTPM]":"219.1","Cell RNA - RPMI-8226 [nTPM]":"281.6","Cell RNA - RPTEC TERT1 [nTPM]":"511.1","Cell RNA - RT4 [nTPM]":"735.0","Cell RNA - SCLC-21H [nTPM]":"5.5","Cell RNA - SH-SY5Y [nTPM]":"91.3","Cell RNA - SiHa [nTPM]":"296.3","Cell RNA - SK-BR-3 [nTPM]":"120.3","Cell RNA - SK-MEL-30 [nTPM]":"298.0","Cell RNA - SuSa [nTPM]":"359.6","Cell RNA - T-47d [nTPM]":"205.2","Cell RNA - THP-1 [nTPM]":"225.7","Cell RNA - TIME [nTPM]":"268.9","Cell RNA - U-138 MG [nTPM]":"291.9","Cell RNA - U-2 OS [nTPM]":"342.0","Cell RNA - U-2197 [nTPM]":"396.1","Cell RNA - U-251 MG [nTPM]":"188.2","Cell RNA - U-266\/70 [nTPM]":"253.7","Cell RNA - U-266\/84 [nTPM]":"452.5","Cell RNA - U-698 [nTPM]":"24.2","Cell RNA - U-87 MG [nTPM]":"292.1","Cell RNA - U-937 [nTPM]":"168.4","Cell RNA - WM-115 [nTPM]":"163.4","Blood RNA - basophil [nTPM]":"668.7","Blood RNA - classical monocyte [nTPM]":"1300.7","Blood RNA - eosinophil [nTPM]":"274.1","Blood RNA - gdT-cell [nTPM]":"92.2","Blood RNA - intermediate monocyte [nTPM]":"1772.7","Blood RNA - MAIT T-cell [nTPM]":"87.9","Blood RNA - memory B-cell [nTPM]":"295.2","Blood RNA - memory CD4 T-cell [nTPM]":"126.5","Blood RNA - memory CD8 T-cell [nTPM]":"92.3","Blood RNA - myeloid DC [nTPM]":"587.8","Blood RNA - naive B-cell [nTPM]":"241.8","Blood RNA - naive CD4 T-cell [nTPM]":"120.9","Blood RNA - naive CD8 T-cell [nTPM]":"100.5","Blood RNA - neutrophil [nTPM]":"674.2","Blood RNA - NK-cell [nTPM]":"99.5","Blood RNA - non-classical monocyte [nTPM]":"1252.1","Blood RNA - plasmacytoid DC [nTPM]":"2113.2","Blood RNA - T-reg [nTPM]":"187.8","Blood RNA - total PBMC [nTPM]":"1304.5","Brain RNA - amygdala [nTPM]":"127.1","Brain RNA - basal ganglia [nTPM]":"145.4","Brain RNA - cerebellum [nTPM]":"152.2","Brain RNA - cerebral cortex [nTPM]":"190.6","Brain RNA - hippocampal formation [nTPM]":"118.1","Brain RNA - hypothalamus [nTPM]":"156.9","Brain RNA - medulla oblongata [nTPM]":"185.7","Brain RNA - midbrain [nTPM]":"145.6","Brain RNA - pons [nTPM]":"179.2","Brain RNA - spinal cord [nTPM]":"151.1","Brain RNA - thalamus [nTPM]":"172.1","Brain RNA - white matter [nTPM]":"195.5","Single Cell Type RNA - Adipocytes [nTPM]":"154.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"381.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2034.2","Single Cell Type RNA - Astrocytes [nTPM]":"11.1","Single Cell Type RNA - B-cells [nTPM]":"160.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"374.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"557.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1074.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"170.2","Single Cell Type RNA - Bipolar cells [nTPM]":"9.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"138.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"220.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"55.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"163.0","Single Cell Type RNA - Club cells [nTPM]":"626.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"331.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"228.3","Single Cell Type RNA - dendritic cells [nTPM]":"664.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"301.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"305.2","Single Cell Type RNA - Ductal cells [nTPM]":"500.4","Single Cell Type RNA - Early spermatids [nTPM]":"90.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"123.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"168.5","Single Cell Type RNA - Endothelial cells [nTPM]":"276.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"119.7","Single Cell Type RNA - Erythroid cells [nTPM]":"65.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"279.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"803.3","Single Cell Type RNA - Fibroblasts [nTPM]":"318.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"61.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"161.0","Single Cell Type RNA - granulocytes [nTPM]":"341.4","Single Cell Type RNA - Granulosa cells [nTPM]":"104.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"447.3","Single Cell Type RNA - Hepatocytes [nTPM]":"195.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"2898.5","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"264.8","Single Cell Type RNA - Ionocytes [nTPM]":"832.1","Single Cell Type RNA - Kupffer cells [nTPM]":"2035.4","Single Cell Type RNA - Langerhans cells [nTPM]":"750.9","Single Cell Type RNA - Late spermatids [nTPM]":"69.6","Single Cell Type RNA - Leydig cells [nTPM]":"566.7","Single Cell Type RNA - Macrophages [nTPM]":"1462.6","Single Cell Type RNA - Melanocytes [nTPM]":"602.9","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"790.5","Single Cell Type RNA - Muller glia cells [nTPM]":"167.4","Single Cell Type RNA - NK-cells [nTPM]":"117.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"24.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"368.3","Single Cell Type RNA - Paneth cells [nTPM]":"405.1","Single Cell Type RNA - Peritubular cells [nTPM]":"291.9","Single Cell Type RNA - Plasma cells [nTPM]":"287.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"357.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"298.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"969.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"393.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"25.1","Single Cell Type RNA - Sertoli cells [nTPM]":"131.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"118.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"155.9","Single Cell Type RNA - Spermatocytes [nTPM]":"268.1","Single Cell Type RNA - Spermatogonia [nTPM]":"166.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"182.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"320.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"210.4","Single Cell Type RNA - T-cells [nTPM]":"109.9","Single Cell Type RNA - Theca cells [nTPM]":"330.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"298.5","Single Cell Type RNA - Urothelial cells [nTPM]":"521.6"},{"Gene":"NPHS1","Gene synonym":["CNF","NPHN"],"Ensembl":"ENSG00000161270","Gene description":"NPHS1 adhesion molecule, nephrin","Uniprot":["O60500"],"Chromosome":"19","Position":"35825372-35869287","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion","Myogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"kidney":"41.5","pancreas":"22.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"5.0","Early spermatids":"13.5","Endometrial ciliated cells":"4.5","Fibroblasts":"5.1","Glandular and luminal cells":"12.1","Late spermatids":"6.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"0.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"1.1","JURKAT":"1.0"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB035555"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB035555":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"0.9","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.8","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"41.5","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"3.9","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"22.8","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.5","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.7","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"0.7","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"2.2","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"1.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.9","Brain RNA - cerebellum [nTPM]":"0.8","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.5","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"0.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"5.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"13.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"5.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"2.1","Single Cell Type RNA - Late spermatids [nTPM]":"6.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"2.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"NPHS2","Gene synonym":["PDCN","SRN1"],"Ensembl":"ENSG00000116218","Gene description":"NPHS2 stomatin family member, podocin","Uniprot":["Q9NP85"],"Chromosome":"1","Position":"179550539-179575952","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"140","RNA tissue specific nTPM":{"kidney":"255.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Collecting duct cells":"20.2","Early spermatids":"9.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"12","RNA cell line specific nTPM":{"NTERA-2":"1.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037267","HPA049486"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB037267":"AB_261982","HPA049486":"AB_2680788"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"255.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"1.8","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"9.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"NPSR1","Gene synonym":["GPR154","GPRA","PGR14"],"Ensembl":"ENSG00000187258","Gene description":"Neuropeptide S receptor 1","Uniprot":["Q6W5P4"],"Chromosome":"7","Position":"34658218-34878332","Protein class":["Disease related genes","G-protein coupled receptors","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Asthma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"1.1","Early spermatids":"4.4","Excitatory neurons":"3.8","Inhibitory neurons":"2.2","Late spermatids":"2.1","Oligodendrocyte precursor cells":"1.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"colorectal cancer":"2.3","pancreatic cancer":"2.0","stomach cancer":"2.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HAP1":"1.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"midbrain":"6.2"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"1.6","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.6","Tissue RNA - midbrain [nTPM]":"1.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"1.3","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"1.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"1.6","Brain RNA - medulla oblongata [nTPM]":"0.6","Brain RNA - midbrain [nTPM]":"1.1","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"1.3","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"4.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"NRAS","Gene synonym":["N-ras"],"Ensembl":"ENSG00000213281","Gene description":"NRAS proto-oncogene, GTPase","Uniprot":["P01111"],"Chromosome":"1","Position":"114704469-114716771","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010157","HPA049830","CAB079912"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 16: Pancreatic endocrine cells - Mixed function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB010157":"AB_632073","CAB079912":"AB_2784586","HPA049830":"AB_2680903"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.59e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.03e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.36e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.87e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Tissue RNA - adipose tissue [nTPM]":"19.0","Tissue RNA - adrenal gland [nTPM]":"9.1","Tissue RNA - amygdala [nTPM]":"10.3","Tissue RNA - appendix [nTPM]":"25.7","Tissue RNA - basal ganglia [nTPM]":"11.2","Tissue RNA - bone marrow [nTPM]":"58.5","Tissue RNA - breast [nTPM]":"18.0","Tissue RNA - cerebellum [nTPM]":"11.5","Tissue RNA - cerebral cortex [nTPM]":"12.3","Tissue RNA - cervix [nTPM]":"12.5","Tissue RNA - choroid plexus [nTPM]":"8.6","Tissue RNA - colon [nTPM]":"27.8","Tissue RNA - duodenum [nTPM]":"21.5","Tissue RNA - endometrium 1 [nTPM]":"12.4","Tissue RNA - epididymis [nTPM]":"7.8","Tissue RNA - esophagus [nTPM]":"20.7","Tissue RNA - fallopian tube [nTPM]":"10.3","Tissue RNA - gallbladder [nTPM]":"17.2","Tissue RNA - heart muscle [nTPM]":"8.3","Tissue RNA - hippocampal formation [nTPM]":"10.2","Tissue RNA - hypothalamus [nTPM]":"12.2","Tissue RNA - kidney [nTPM]":"20.9","Tissue RNA - liver [nTPM]":"24.9","Tissue RNA - lung [nTPM]":"18.5","Tissue RNA - lymph node [nTPM]":"30.4","Tissue RNA - medulla oblongata [nTPM]":"12.3","Tissue RNA - midbrain [nTPM]":"12.1","Tissue RNA - ovary [nTPM]":"9.6","Tissue RNA - pancreas [nTPM]":"11.4","Tissue RNA - parathyroid gland [nTPM]":"9.0","Tissue RNA - pituitary gland [nTPM]":"4.3","Tissue RNA - placenta [nTPM]":"28.3","Tissue RNA - pons [nTPM]":"12.3","Tissue RNA - prostate [nTPM]":"11.4","Tissue RNA - rectum [nTPM]":"26.6","Tissue RNA - retina [nTPM]":"6.6","Tissue RNA - salivary gland [nTPM]":"10.9","Tissue RNA - seminal vesicle [nTPM]":"7.1","Tissue RNA - skeletal muscle [nTPM]":"7.7","Tissue RNA - skin 1 [nTPM]":"19.8","Tissue RNA - small intestine [nTPM]":"22.5","Tissue RNA - smooth muscle [nTPM]":"14.1","Tissue RNA - spinal cord [nTPM]":"11.7","Tissue RNA - spleen [nTPM]":"18.6","Tissue RNA - stomach 1 [nTPM]":"21.8","Tissue RNA - testis [nTPM]":"9.6","Tissue RNA - thalamus [nTPM]":"11.4","Tissue RNA - thymus [nTPM]":"39.0","Tissue RNA - thyroid gland [nTPM]":"16.1","Tissue RNA - tongue [nTPM]":"7.8","Tissue RNA - tonsil [nTPM]":"29.7","Tissue RNA - urinary bladder [nTPM]":"22.2","Tissue RNA - vagina [nTPM]":"8.6","Tissue RNA - white matter [nTPM]":"13.4","Cell RNA - A-431 [nTPM]":"93.7","Cell RNA - A549 [nTPM]":"24.9","Cell RNA - AF22 [nTPM]":"65.2","Cell RNA - AN3-CA [nTPM]":"24.9","Cell RNA - ASC diff [nTPM]":"26.4","Cell RNA - ASC TERT1 [nTPM]":"56.3","Cell RNA - BEWO [nTPM]":"46.5","Cell RNA - BJ [nTPM]":"43.5","Cell RNA - BJ hTERT+ [nTPM]":"48.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"79.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"89.0","Cell RNA - CACO-2 [nTPM]":"50.4","Cell RNA - CAPAN-2 [nTPM]":"33.9","Cell RNA - Daudi [nTPM]":"70.4","Cell RNA - EFO-21 [nTPM]":"56.3","Cell RNA - fHDF\/TERT166 [nTPM]":"58.9","Cell RNA - GAMG [nTPM]":"55.4","Cell RNA - HaCaT [nTPM]":"26.0","Cell RNA - HAP1 [nTPM]":"88.2","Cell RNA - HBEC3-KT [nTPM]":"70.6","Cell RNA - HBF TERT88 [nTPM]":"113.4","Cell RNA - HDLM-2 [nTPM]":"96.5","Cell RNA - HEK 293 [nTPM]":"34.2","Cell RNA - HEL [nTPM]":"47.8","Cell RNA - HeLa [nTPM]":"34.5","Cell RNA - Hep G2 [nTPM]":"60.2","Cell RNA - HHSteC [nTPM]":"52.3","Cell RNA - HL-60 [nTPM]":"120.0","Cell RNA - HMC-1 [nTPM]":"71.0","Cell RNA - HSkMC [nTPM]":"51.1","Cell RNA - hTCEpi [nTPM]":"56.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"91.5","Cell RNA - hTERT-HME1 [nTPM]":"66.2","Cell RNA - hTERT-RPE1 [nTPM]":"25.0","Cell RNA - HUVEC TERT2 [nTPM]":"102.8","Cell RNA - JURKAT [nTPM]":"54.6","Cell RNA - K-562 [nTPM]":"77.3","Cell RNA - Karpas-707 [nTPM]":"78.5","Cell RNA - LHCN-M2 [nTPM]":"71.0","Cell RNA - MCF7 [nTPM]":"248.9","Cell RNA - MOLT-4 [nTPM]":"83.5","Cell RNA - NB-4 [nTPM]":"46.4","Cell RNA - NTERA-2 [nTPM]":"111.0","Cell RNA - OE19 [nTPM]":"30.2","Cell RNA - PC-3 [nTPM]":"17.9","Cell RNA - REH [nTPM]":"62.9","Cell RNA - RH-30 [nTPM]":"116.0","Cell RNA - RPMI-8226 [nTPM]":"44.1","Cell RNA - RPTEC TERT1 [nTPM]":"70.6","Cell RNA - RT4 [nTPM]":"49.5","Cell RNA - SCLC-21H [nTPM]":"39.4","Cell RNA - SH-SY5Y [nTPM]":"59.0","Cell RNA - SiHa [nTPM]":"44.7","Cell RNA - SK-BR-3 [nTPM]":"36.4","Cell RNA - SK-MEL-30 [nTPM]":"107.1","Cell RNA - SuSa [nTPM]":"75.4","Cell RNA - T-47d [nTPM]":"31.9","Cell RNA - THP-1 [nTPM]":"96.2","Cell RNA - TIME [nTPM]":"79.2","Cell RNA - U-138 MG [nTPM]":"43.3","Cell RNA - U-2 OS [nTPM]":"82.2","Cell RNA - U-2197 [nTPM]":"81.5","Cell RNA - U-251 MG [nTPM]":"90.3","Cell RNA - U-266\/70 [nTPM]":"137.7","Cell RNA - U-266\/84 [nTPM]":"101.6","Cell RNA - U-698 [nTPM]":"81.6","Cell RNA - U-87 MG [nTPM]":"86.4","Cell RNA - U-937 [nTPM]":"64.6","Cell RNA - WM-115 [nTPM]":"159.0","Blood RNA - basophil [nTPM]":"38.7","Blood RNA - classical monocyte [nTPM]":"12.8","Blood RNA - eosinophil [nTPM]":"12.6","Blood RNA - gdT-cell [nTPM]":"11.7","Blood RNA - intermediate monocyte [nTPM]":"19.2","Blood RNA - MAIT T-cell [nTPM]":"10.5","Blood RNA - memory B-cell [nTPM]":"12.8","Blood RNA - memory CD4 T-cell [nTPM]":"9.3","Blood RNA - memory CD8 T-cell [nTPM]":"11.6","Blood RNA - myeloid DC [nTPM]":"12.6","Blood RNA - naive B-cell [nTPM]":"10.5","Blood RNA - naive CD4 T-cell [nTPM]":"9.9","Blood RNA - naive CD8 T-cell [nTPM]":"12.9","Blood RNA - neutrophil [nTPM]":"3.4","Blood RNA - NK-cell [nTPM]":"15.5","Blood RNA - non-classical monocyte [nTPM]":"17.6","Blood RNA - plasmacytoid DC [nTPM]":"9.6","Blood RNA - T-reg [nTPM]":"13.4","Blood RNA - total PBMC [nTPM]":"13.1","Brain RNA - amygdala [nTPM]":"10.3","Brain RNA - basal ganglia [nTPM]":"11.2","Brain RNA - cerebellum [nTPM]":"11.5","Brain RNA - cerebral cortex [nTPM]":"12.3","Brain RNA - hippocampal formation [nTPM]":"10.2","Brain RNA - hypothalamus [nTPM]":"12.2","Brain RNA - medulla oblongata [nTPM]":"12.3","Brain RNA - midbrain [nTPM]":"12.1","Brain RNA - pons [nTPM]":"12.3","Brain RNA - spinal cord [nTPM]":"11.7","Brain RNA - thalamus [nTPM]":"11.4","Brain RNA - white matter [nTPM]":"13.4","Single Cell Type RNA - Adipocytes [nTPM]":"22.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.5","Single Cell Type RNA - Astrocytes [nTPM]":"8.1","Single Cell Type RNA - B-cells [nTPM]":"25.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"31.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"23.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Bipolar cells [nTPM]":"5.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"19.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"22.4","Single Cell Type RNA - dendritic cells [nTPM]":"27.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"49.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"34.1","Single Cell Type RNA - Early spermatids [nTPM]":"3.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"24.7","Single Cell Type RNA - Endothelial cells [nTPM]":"29.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"24.6","Single Cell Type RNA - Erythroid cells [nTPM]":"31.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"31.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"50.4","Single Cell Type RNA - Fibroblasts [nTPM]":"16.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"29.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"38.0","Single Cell Type RNA - granulocytes [nTPM]":"31.1","Single Cell Type RNA - Granulosa cells [nTPM]":"22.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"33.2","Single Cell Type RNA - Hepatocytes [nTPM]":"29.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"49.2","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.1","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"44.9","Single Cell Type RNA - Langerhans cells [nTPM]":"30.7","Single Cell Type RNA - Late spermatids [nTPM]":"5.9","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"30.4","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"41.6","Single Cell Type RNA - Muller glia cells [nTPM]":"7.8","Single Cell Type RNA - NK-cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"51.4","Single Cell Type RNA - Paneth cells [nTPM]":"32.9","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"39.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"28.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"39.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.3","Single Cell Type RNA - Spermatocytes [nTPM]":"7.3","Single Cell Type RNA - Spermatogonia [nTPM]":"15.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"24.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"36.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"31.2","Single Cell Type RNA - T-cells [nTPM]":"21.9","Single Cell Type RNA - Theca cells [nTPM]":"13.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"28.8","Single Cell Type RNA - Urothelial cells [nTPM]":"40.2"},{"Gene":"NRXN1","Gene synonym":["Hs.22998","KIAA0578"],"Ensembl":"ENSG00000179915","Gene description":"Neurexin 1","Uniprot":["P58400","Q9ULB1"],"Chromosome":"2","Position":"49918503-51225575","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Angiogenesis","Cell adhesion"],"Molecular function":null,"Disease involvement":["Mental retardation","Schizophrenia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"brain":"145.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Astrocytes":"4025.1","Excitatory neurons":"3206.3","Inhibitory neurons":"2116.2","Oligodendrocyte precursor cells":"4897.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"glioma":"3.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"neutrophil":"1.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"granulocytes":"1.3"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"SCLC-21H":"31.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071400"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1400000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA071400":"AB_2732180"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-3"},"Tissue RNA - adipose tissue [nTPM]":"1.1","Tissue RNA - adrenal gland [nTPM]":"2.0","Tissue RNA - amygdala [nTPM]":"40.9","Tissue RNA - appendix [nTPM]":"1.1","Tissue RNA - basal ganglia [nTPM]":"60.9","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"0.8","Tissue RNA - cerebellum [nTPM]":"145.0","Tissue RNA - cerebral cortex [nTPM]":"74.4","Tissue RNA - cervix [nTPM]":"2.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"11.3","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"1.1","Tissue RNA - epididymis [nTPM]":"3.0","Tissue RNA - esophagus [nTPM]":"2.0","Tissue RNA - fallopian tube [nTPM]":"0.8","Tissue RNA - gallbladder [nTPM]":"1.2","Tissue RNA - heart muscle [nTPM]":"5.2","Tissue RNA - hippocampal formation [nTPM]":"62.7","Tissue RNA - hypothalamus [nTPM]":"16.8","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"0.5","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"2.2","Tissue RNA - ovary [nTPM]":"0.9","Tissue RNA - pancreas [nTPM]":"1.4","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"6.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"7.2","Tissue RNA - prostate [nTPM]":"2.8","Tissue RNA - rectum [nTPM]":"2.6","Tissue RNA - retina [nTPM]":"7.2","Tissue RNA - salivary gland [nTPM]":"2.4","Tissue RNA - seminal vesicle [nTPM]":"8.4","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"2.6","Tissue RNA - smooth muscle [nTPM]":"1.0","Tissue RNA - spinal cord [nTPM]":"4.7","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"2.3","Tissue RNA - testis [nTPM]":"5.6","Tissue RNA - thalamus [nTPM]":"15.7","Tissue RNA - thymus [nTPM]":"1.2","Tissue RNA - thyroid gland [nTPM]":"0.6","Tissue RNA - tongue [nTPM]":"0.8","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"2.3","Tissue RNA - vagina [nTPM]":"3.1","Tissue RNA - white matter [nTPM]":"22.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"1.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"3.5","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"4.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"31.3","Cell RNA - SH-SY5Y [nTPM]":"1.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.7","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"3.1","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"40.9","Brain RNA - basal ganglia [nTPM]":"60.9","Brain RNA - cerebellum [nTPM]":"145.0","Brain RNA - cerebral cortex [nTPM]":"74.4","Brain RNA - hippocampal formation [nTPM]":"62.7","Brain RNA - hypothalamus [nTPM]":"16.8","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"2.2","Brain RNA - pons [nTPM]":"7.2","Brain RNA - spinal cord [nTPM]":"4.7","Brain RNA - thalamus [nTPM]":"15.7","Brain RNA - white matter [nTPM]":"22.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"4025.1","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"116.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"201.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.8","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3206.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"77.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2116.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.6","Single Cell Type RNA - Late spermatids [nTPM]":"103.4","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"174.3","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"22.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4897.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"678.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"1.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.3","Single Cell Type RNA - Spermatocytes [nTPM]":"13.3","Single Cell Type RNA - Spermatogonia [nTPM]":"5.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"NSD1","Gene synonym":["ARA267","FLJ22263","KMT3B","STO"],"Ensembl":"ENSG00000165671","Gene description":"Nuclear receptor binding SET domain protein 1","Uniprot":["Q96L73"],"Chromosome":"5","Position":"177133025-177300213","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","Chromatin regulator","Methyltransferase","Repressor","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048431","HPA070333","HPA073705"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA048431":"AB_2680388","HPA070333":"AB_2686255","HPA073705":"AB_2732239"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.77e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.32e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.7","Tissue RNA - adrenal gland [nTPM]":"7.2","Tissue RNA - amygdala [nTPM]":"8.9","Tissue RNA - appendix [nTPM]":"12.0","Tissue RNA - basal ganglia [nTPM]":"13.4","Tissue RNA - bone marrow [nTPM]":"21.2","Tissue RNA - breast [nTPM]":"10.9","Tissue RNA - cerebellum [nTPM]":"26.2","Tissue RNA - cerebral cortex [nTPM]":"10.4","Tissue RNA - cervix [nTPM]":"11.1","Tissue RNA - choroid plexus [nTPM]":"9.8","Tissue RNA - colon [nTPM]":"10.1","Tissue RNA - duodenum [nTPM]":"8.4","Tissue RNA - endometrium 1 [nTPM]":"11.5","Tissue RNA - epididymis [nTPM]":"10.3","Tissue RNA - esophagus [nTPM]":"11.4","Tissue RNA - fallopian tube [nTPM]":"10.1","Tissue RNA - gallbladder [nTPM]":"8.0","Tissue RNA - heart muscle [nTPM]":"9.1","Tissue RNA - hippocampal formation [nTPM]":"7.7","Tissue RNA - hypothalamus [nTPM]":"10.0","Tissue RNA - kidney [nTPM]":"10.6","Tissue RNA - liver [nTPM]":"6.6","Tissue RNA - lung [nTPM]":"9.2","Tissue RNA - lymph node [nTPM]":"13.7","Tissue RNA - medulla oblongata [nTPM]":"9.7","Tissue RNA - midbrain [nTPM]":"10.8","Tissue RNA - ovary [nTPM]":"12.3","Tissue RNA - pancreas [nTPM]":"11.3","Tissue RNA - parathyroid gland [nTPM]":"12.8","Tissue RNA - pituitary gland [nTPM]":"9.0","Tissue RNA - placenta [nTPM]":"10.7","Tissue RNA - pons [nTPM]":"12.2","Tissue RNA - prostate [nTPM]":"9.3","Tissue RNA - rectum [nTPM]":"10.8","Tissue RNA - retina [nTPM]":"11.9","Tissue RNA - salivary gland [nTPM]":"10.4","Tissue RNA - seminal vesicle [nTPM]":"9.6","Tissue RNA - skeletal muscle [nTPM]":"13.6","Tissue RNA - skin 1 [nTPM]":"12.0","Tissue RNA - small intestine [nTPM]":"9.4","Tissue RNA - smooth muscle [nTPM]":"12.0","Tissue RNA - spinal cord [nTPM]":"6.6","Tissue RNA - spleen [nTPM]":"11.3","Tissue RNA - stomach 1 [nTPM]":"8.9","Tissue RNA - testis [nTPM]":"23.2","Tissue RNA - thalamus [nTPM]":"12.0","Tissue RNA - thymus [nTPM]":"20.2","Tissue RNA - thyroid gland [nTPM]":"15.5","Tissue RNA - tongue [nTPM]":"11.5","Tissue RNA - tonsil [nTPM]":"14.7","Tissue RNA - urinary bladder [nTPM]":"9.3","Tissue RNA - vagina [nTPM]":"7.9","Tissue RNA - white matter [nTPM]":"17.5","Cell RNA - A-431 [nTPM]":"20.5","Cell RNA - A549 [nTPM]":"25.9","Cell RNA - AF22 [nTPM]":"26.0","Cell RNA - AN3-CA [nTPM]":"22.8","Cell RNA - ASC diff [nTPM]":"12.5","Cell RNA - ASC TERT1 [nTPM]":"16.1","Cell RNA - BEWO [nTPM]":"0.9","Cell RNA - BJ [nTPM]":"18.2","Cell RNA - BJ hTERT+ [nTPM]":"17.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"22.8","Cell RNA - CACO-2 [nTPM]":"5.7","Cell RNA - CAPAN-2 [nTPM]":"16.6","Cell RNA - Daudi [nTPM]":"41.7","Cell RNA - EFO-21 [nTPM]":"19.9","Cell RNA - fHDF\/TERT166 [nTPM]":"24.8","Cell RNA - GAMG [nTPM]":"22.7","Cell RNA - HaCaT [nTPM]":"17.0","Cell RNA - HAP1 [nTPM]":"41.9","Cell RNA - HBEC3-KT [nTPM]":"40.0","Cell RNA - HBF TERT88 [nTPM]":"29.7","Cell RNA - HDLM-2 [nTPM]":"72.9","Cell RNA - HEK 293 [nTPM]":"25.9","Cell RNA - HEL [nTPM]":"18.6","Cell RNA - HeLa [nTPM]":"29.5","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"20.7","Cell RNA - HL-60 [nTPM]":"40.4","Cell RNA - HMC-1 [nTPM]":"21.2","Cell RNA - HSkMC [nTPM]":"15.2","Cell RNA - hTCEpi [nTPM]":"23.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"29.4","Cell RNA - hTERT-HME1 [nTPM]":"27.3","Cell RNA - hTERT-RPE1 [nTPM]":"17.5","Cell RNA - HUVEC TERT2 [nTPM]":"36.4","Cell RNA - JURKAT [nTPM]":"26.0","Cell RNA - K-562 [nTPM]":"25.9","Cell RNA - Karpas-707 [nTPM]":"14.3","Cell RNA - LHCN-M2 [nTPM]":"25.2","Cell RNA - MCF7 [nTPM]":"42.3","Cell RNA - MOLT-4 [nTPM]":"28.3","Cell RNA - NB-4 [nTPM]":"13.1","Cell RNA - NTERA-2 [nTPM]":"28.5","Cell RNA - OE19 [nTPM]":"13.7","Cell RNA - PC-3 [nTPM]":"22.5","Cell RNA - REH [nTPM]":"31.0","Cell RNA - RH-30 [nTPM]":"3.4","Cell RNA - RPMI-8226 [nTPM]":"12.9","Cell RNA - RPTEC TERT1 [nTPM]":"15.9","Cell RNA - RT4 [nTPM]":"24.4","Cell RNA - SCLC-21H [nTPM]":"31.6","Cell RNA - SH-SY5Y [nTPM]":"21.9","Cell RNA - SiHa [nTPM]":"46.7","Cell RNA - SK-BR-3 [nTPM]":"20.1","Cell RNA - SK-MEL-30 [nTPM]":"13.8","Cell RNA - SuSa [nTPM]":"24.1","Cell RNA - T-47d [nTPM]":"20.2","Cell RNA - THP-1 [nTPM]":"33.0","Cell RNA - TIME [nTPM]":"27.4","Cell RNA - U-138 MG [nTPM]":"17.1","Cell RNA - U-2 OS [nTPM]":"25.0","Cell RNA - U-2197 [nTPM]":"11.0","Cell RNA - U-251 MG [nTPM]":"22.6","Cell RNA - U-266\/70 [nTPM]":"16.7","Cell RNA - U-266\/84 [nTPM]":"15.7","Cell RNA - U-698 [nTPM]":"29.5","Cell RNA - U-87 MG [nTPM]":"9.9","Cell RNA - U-937 [nTPM]":"19.3","Cell RNA - WM-115 [nTPM]":"18.7","Blood RNA - basophil [nTPM]":"14.7","Blood RNA - classical monocyte [nTPM]":"9.0","Blood RNA - eosinophil [nTPM]":"10.5","Blood RNA - gdT-cell [nTPM]":"7.2","Blood RNA - intermediate monocyte [nTPM]":"6.1","Blood RNA - MAIT T-cell [nTPM]":"6.0","Blood RNA - memory B-cell [nTPM]":"8.5","Blood RNA - memory CD4 T-cell [nTPM]":"6.1","Blood RNA - memory CD8 T-cell [nTPM]":"5.0","Blood RNA - myeloid DC [nTPM]":"7.2","Blood RNA - naive B-cell [nTPM]":"10.3","Blood RNA - naive CD4 T-cell [nTPM]":"7.5","Blood RNA - naive CD8 T-cell [nTPM]":"6.0","Blood RNA - neutrophil [nTPM]":"18.6","Blood RNA - NK-cell [nTPM]":"11.3","Blood RNA - non-classical monocyte [nTPM]":"12.2","Blood RNA - plasmacytoid DC [nTPM]":"9.4","Blood RNA - T-reg [nTPM]":"6.4","Blood RNA - total PBMC [nTPM]":"3.4","Brain RNA - amygdala [nTPM]":"8.9","Brain RNA - basal ganglia [nTPM]":"13.4","Brain RNA - cerebellum [nTPM]":"26.2","Brain RNA - cerebral cortex [nTPM]":"10.4","Brain RNA - hippocampal formation [nTPM]":"7.7","Brain RNA - hypothalamus [nTPM]":"10.0","Brain RNA - medulla oblongata [nTPM]":"9.7","Brain RNA - midbrain [nTPM]":"10.8","Brain RNA - pons [nTPM]":"12.2","Brain RNA - spinal cord [nTPM]":"6.6","Brain RNA - thalamus [nTPM]":"12.0","Brain RNA - white matter [nTPM]":"17.5","Single Cell Type RNA - Adipocytes [nTPM]":"37.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.4","Single Cell Type RNA - Astrocytes [nTPM]":"84.9","Single Cell Type RNA - B-cells [nTPM]":"71.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"27.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"34.1","Single Cell Type RNA - Bipolar cells [nTPM]":"94.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"25.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"44.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"34.3","Single Cell Type RNA - Club cells [nTPM]":"35.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"55.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"150.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"43.6","Single Cell Type RNA - dendritic cells [nTPM]":"66.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"19.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"27.8","Single Cell Type RNA - Early spermatids [nTPM]":"31.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"65.7","Single Cell Type RNA - Endothelial cells [nTPM]":"36.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"41.9","Single Cell Type RNA - Erythroid cells [nTPM]":"48.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"107.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"23.7","Single Cell Type RNA - Fibroblasts [nTPM]":"32.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"41.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"41.9","Single Cell Type RNA - granulocytes [nTPM]":"41.7","Single Cell Type RNA - Granulosa cells [nTPM]":"64.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"33.5","Single Cell Type RNA - Hepatocytes [nTPM]":"19.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"27.7","Single Cell Type RNA - Horizontal cells [nTPM]":"89.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"110.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"25.6","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"36.8","Single Cell Type RNA - Langerhans cells [nTPM]":"25.7","Single Cell Type RNA - Late spermatids [nTPM]":"50.3","Single Cell Type RNA - Leydig cells [nTPM]":"51.0","Single Cell Type RNA - Macrophages [nTPM]":"47.1","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"115.2","Single Cell Type RNA - monocytes [nTPM]":"75.0","Single Cell Type RNA - Muller glia cells [nTPM]":"29.2","Single Cell Type RNA - NK-cells [nTPM]":"95.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"140.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"157.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"23.7","Single Cell Type RNA - Paneth cells [nTPM]":"31.0","Single Cell Type RNA - Peritubular cells [nTPM]":"33.1","Single Cell Type RNA - Plasma cells [nTPM]":"55.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"29.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"33.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"112.3","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"42.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"36.1","Single Cell Type RNA - Spermatocytes [nTPM]":"83.7","Single Cell Type RNA - Spermatogonia [nTPM]":"62.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"41.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"35.4","Single Cell Type RNA - T-cells [nTPM]":"62.0","Single Cell Type RNA - Theca cells [nTPM]":"55.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"28.2","Single Cell Type RNA - Urothelial cells [nTPM]":"30.0"},{"Gene":"NSD2","Gene synonym":["KMT3G","MMSET","WHSC1"],"Ensembl":"ENSG00000109685","Gene description":"Nuclear receptor binding SET domain protein 2","Uniprot":["O96028"],"Chromosome":"4","Position":"1871393-1982207","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Methyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Glandular and luminal cells":"20.3","Granulosa cells":"69.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015801","CAB068246","CAB068247"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB068246":"AB_2665690","CAB068247":"AB_2665689","HPA015801":"AB_1858830"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.61e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.19e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.1","Tissue RNA - adrenal gland [nTPM]":"8.4","Tissue RNA - amygdala [nTPM]":"12.7","Tissue RNA - appendix [nTPM]":"16.5","Tissue RNA - basal ganglia [nTPM]":"13.0","Tissue RNA - bone marrow [nTPM]":"54.9","Tissue RNA - breast [nTPM]":"9.9","Tissue RNA - cerebellum [nTPM]":"23.6","Tissue RNA - cerebral cortex [nTPM]":"15.2","Tissue RNA - cervix [nTPM]":"9.4","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"19.6","Tissue RNA - duodenum [nTPM]":"18.6","Tissue RNA - endometrium 1 [nTPM]":"10.7","Tissue RNA - epididymis [nTPM]":"7.3","Tissue RNA - esophagus [nTPM]":"13.6","Tissue RNA - fallopian tube [nTPM]":"8.4","Tissue RNA - gallbladder [nTPM]":"8.3","Tissue RNA - heart muscle [nTPM]":"15.8","Tissue RNA - hippocampal formation [nTPM]":"11.8","Tissue RNA - hypothalamus [nTPM]":"11.5","Tissue RNA - kidney [nTPM]":"9.8","Tissue RNA - liver [nTPM]":"8.3","Tissue RNA - lung [nTPM]":"12.6","Tissue RNA - lymph node [nTPM]":"25.4","Tissue RNA - medulla oblongata [nTPM]":"9.8","Tissue RNA - midbrain [nTPM]":"8.6","Tissue RNA - ovary [nTPM]":"7.7","Tissue RNA - pancreas [nTPM]":"13.5","Tissue RNA - parathyroid gland [nTPM]":"12.0","Tissue RNA - pituitary gland [nTPM]":"13.8","Tissue RNA - placenta [nTPM]":"12.2","Tissue RNA - pons [nTPM]":"12.0","Tissue RNA - prostate [nTPM]":"9.7","Tissue RNA - rectum [nTPM]":"22.5","Tissue RNA - retina [nTPM]":"28.5","Tissue RNA - salivary gland [nTPM]":"11.6","Tissue RNA - seminal vesicle [nTPM]":"8.4","Tissue RNA - skeletal muscle [nTPM]":"16.7","Tissue RNA - skin 1 [nTPM]":"11.6","Tissue RNA - small intestine [nTPM]":"18.3","Tissue RNA - smooth muscle [nTPM]":"12.4","Tissue RNA - spinal cord [nTPM]":"4.4","Tissue RNA - spleen [nTPM]":"14.1","Tissue RNA - stomach 1 [nTPM]":"12.5","Tissue RNA - testis [nTPM]":"37.2","Tissue RNA - thalamus [nTPM]":"12.6","Tissue RNA - thymus [nTPM]":"59.8","Tissue RNA - thyroid gland [nTPM]":"17.4","Tissue RNA - tongue [nTPM]":"13.7","Tissue RNA - tonsil [nTPM]":"24.3","Tissue RNA - urinary bladder [nTPM]":"9.7","Tissue RNA - vagina [nTPM]":"9.2","Tissue RNA - white matter [nTPM]":"14.9","Cell RNA - A-431 [nTPM]":"124.0","Cell RNA - A549 [nTPM]":"58.6","Cell RNA - AF22 [nTPM]":"168.3","Cell RNA - AN3-CA [nTPM]":"71.2","Cell RNA - ASC diff [nTPM]":"17.5","Cell RNA - ASC TERT1 [nTPM]":"26.5","Cell RNA - BEWO [nTPM]":"44.2","Cell RNA - BJ [nTPM]":"98.2","Cell RNA - BJ hTERT+ [nTPM]":"85.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"115.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"128.8","Cell RNA - CACO-2 [nTPM]":"44.6","Cell RNA - CAPAN-2 [nTPM]":"141.4","Cell RNA - Daudi [nTPM]":"117.5","Cell RNA - EFO-21 [nTPM]":"31.4","Cell RNA - fHDF\/TERT166 [nTPM]":"78.0","Cell RNA - GAMG [nTPM]":"158.5","Cell RNA - HaCaT [nTPM]":"50.2","Cell RNA - HAP1 [nTPM]":"114.4","Cell RNA - HBEC3-KT [nTPM]":"74.3","Cell RNA - HBF TERT88 [nTPM]":"195.0","Cell RNA - HDLM-2 [nTPM]":"58.3","Cell RNA - HEK 293 [nTPM]":"47.7","Cell RNA - HEL [nTPM]":"151.3","Cell RNA - HeLa [nTPM]":"81.7","Cell RNA - Hep G2 [nTPM]":"25.5","Cell RNA - HHSteC [nTPM]":"18.6","Cell RNA - HL-60 [nTPM]":"89.5","Cell RNA - HMC-1 [nTPM]":"74.9","Cell RNA - HSkMC [nTPM]":"9.9","Cell RNA - hTCEpi [nTPM]":"19.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"101.2","Cell RNA - hTERT-HME1 [nTPM]":"89.9","Cell RNA - hTERT-RPE1 [nTPM]":"60.1","Cell RNA - HUVEC TERT2 [nTPM]":"92.2","Cell RNA - JURKAT [nTPM]":"123.4","Cell RNA - K-562 [nTPM]":"81.7","Cell RNA - Karpas-707 [nTPM]":"132.2","Cell RNA - LHCN-M2 [nTPM]":"95.8","Cell RNA - MCF7 [nTPM]":"42.1","Cell RNA - MOLT-4 [nTPM]":"243.3","Cell RNA - NB-4 [nTPM]":"99.7","Cell RNA - NTERA-2 [nTPM]":"68.8","Cell RNA - OE19 [nTPM]":"60.1","Cell RNA - PC-3 [nTPM]":"77.1","Cell RNA - REH [nTPM]":"137.8","Cell RNA - RH-30 [nTPM]":"106.7","Cell RNA - RPMI-8226 [nTPM]":"42.9","Cell RNA - RPTEC TERT1 [nTPM]":"45.4","Cell RNA - RT4 [nTPM]":"57.4","Cell RNA - SCLC-21H [nTPM]":"115.6","Cell RNA - SH-SY5Y [nTPM]":"82.7","Cell RNA - SiHa [nTPM]":"78.4","Cell RNA - SK-BR-3 [nTPM]":"29.2","Cell RNA - SK-MEL-30 [nTPM]":"31.7","Cell RNA - SuSa [nTPM]":"71.4","Cell RNA - T-47d [nTPM]":"68.9","Cell RNA - THP-1 [nTPM]":"52.2","Cell RNA - TIME [nTPM]":"64.9","Cell RNA - U-138 MG [nTPM]":"109.0","Cell RNA - U-2 OS [nTPM]":"87.4","Cell RNA - U-2197 [nTPM]":"72.8","Cell RNA - U-251 MG [nTPM]":"188.1","Cell RNA - U-266\/70 [nTPM]":"54.1","Cell RNA - U-266\/84 [nTPM]":"72.9","Cell RNA - U-698 [nTPM]":"113.7","Cell RNA - U-87 MG [nTPM]":"66.0","Cell RNA - U-937 [nTPM]":"81.9","Cell RNA - WM-115 [nTPM]":"108.0","Blood RNA - basophil [nTPM]":"4.0","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"1.3","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"1.1","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"1.2","Blood RNA - myeloid DC [nTPM]":"1.2","Blood RNA - naive B-cell [nTPM]":"1.7","Blood RNA - naive CD4 T-cell [nTPM]":"1.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.8","Blood RNA - neutrophil [nTPM]":"3.4","Blood RNA - NK-cell [nTPM]":"1.2","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"2.1","Blood RNA - T-reg [nTPM]":"2.9","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"12.7","Brain RNA - basal ganglia [nTPM]":"13.0","Brain RNA - cerebellum [nTPM]":"23.6","Brain RNA - cerebral cortex [nTPM]":"15.2","Brain RNA - hippocampal formation [nTPM]":"11.8","Brain RNA - hypothalamus [nTPM]":"11.5","Brain RNA - medulla oblongata [nTPM]":"9.8","Brain RNA - midbrain [nTPM]":"8.6","Brain RNA - pons [nTPM]":"12.0","Brain RNA - spinal cord [nTPM]":"4.4","Brain RNA - thalamus [nTPM]":"12.6","Brain RNA - white matter [nTPM]":"14.9","Single Cell Type RNA - Adipocytes [nTPM]":"12.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.4","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"4.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"8.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.7","Single Cell Type RNA - dendritic cells [nTPM]":"7.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"10.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.7","Single Cell Type RNA - Endothelial cells [nTPM]":"6.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.0","Single Cell Type RNA - Fibroblasts [nTPM]":"6.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.3","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"69.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"5.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"5.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"4.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - T-cells [nTPM]":"5.2","Single Cell Type RNA - Theca cells [nTPM]":"3.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"NSD3","Gene synonym":["FLJ20353","KMT3F","WHISTLE","WHSC1L1"],"Ensembl":"ENSG00000147548","Gene description":"Nuclear receptor binding SET domain protein 3","Uniprot":["Q9BZ95"],"Chromosome":"8","Position":"38269704-38382272","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","Methyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"173.8","Syncytiotrophoblasts":"130.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005659","CAB013721","HPA018893"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB013721":null,"HPA005659":"AB_1080596","HPA018893":"AB_1858833"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.48e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Tissue RNA - adipose tissue [nTPM]":"22.4","Tissue RNA - adrenal gland [nTPM]":"14.4","Tissue RNA - amygdala [nTPM]":"10.0","Tissue RNA - appendix [nTPM]":"24.8","Tissue RNA - basal ganglia [nTPM]":"13.7","Tissue RNA - bone marrow [nTPM]":"60.2","Tissue RNA - breast [nTPM]":"23.4","Tissue RNA - cerebellum [nTPM]":"28.4","Tissue RNA - cerebral cortex [nTPM]":"20.5","Tissue RNA - cervix [nTPM]":"24.0","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"22.4","Tissue RNA - duodenum [nTPM]":"24.1","Tissue RNA - endometrium 1 [nTPM]":"22.9","Tissue RNA - epididymis [nTPM]":"17.4","Tissue RNA - esophagus [nTPM]":"22.9","Tissue RNA - fallopian tube [nTPM]":"23.5","Tissue RNA - gallbladder [nTPM]":"24.5","Tissue RNA - heart muscle [nTPM]":"13.7","Tissue RNA - hippocampal formation [nTPM]":"12.8","Tissue RNA - hypothalamus [nTPM]":"22.3","Tissue RNA - kidney [nTPM]":"20.0","Tissue RNA - liver [nTPM]":"16.6","Tissue RNA - lung [nTPM]":"20.6","Tissue RNA - lymph node [nTPM]":"35.3","Tissue RNA - medulla oblongata [nTPM]":"3.1","Tissue RNA - midbrain [nTPM]":"4.8","Tissue RNA - ovary [nTPM]":"36.4","Tissue RNA - pancreas [nTPM]":"20.1","Tissue RNA - parathyroid gland [nTPM]":"24.8","Tissue RNA - pituitary gland [nTPM]":"17.3","Tissue RNA - placenta [nTPM]":"33.5","Tissue RNA - pons [nTPM]":"5.3","Tissue RNA - prostate [nTPM]":"20.9","Tissue RNA - rectum [nTPM]":"26.6","Tissue RNA - retina [nTPM]":"23.3","Tissue RNA - salivary gland [nTPM]":"19.9","Tissue RNA - seminal vesicle [nTPM]":"24.3","Tissue RNA - skeletal muscle [nTPM]":"14.4","Tissue RNA - skin 1 [nTPM]":"19.8","Tissue RNA - small intestine [nTPM]":"26.7","Tissue RNA - smooth muscle [nTPM]":"19.8","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"26.9","Tissue RNA - stomach 1 [nTPM]":"29.0","Tissue RNA - testis [nTPM]":"14.4","Tissue RNA - thalamus [nTPM]":"10.4","Tissue RNA - thymus [nTPM]":"38.3","Tissue RNA - thyroid gland [nTPM]":"27.6","Tissue RNA - tongue [nTPM]":"16.0","Tissue RNA - tonsil [nTPM]":"31.0","Tissue RNA - urinary bladder [nTPM]":"23.3","Tissue RNA - vagina [nTPM]":"23.1","Tissue RNA - white matter [nTPM]":"18.7","Cell RNA - A-431 [nTPM]":"62.1","Cell RNA - A549 [nTPM]":"34.9","Cell RNA - AF22 [nTPM]":"58.7","Cell RNA - AN3-CA [nTPM]":"39.9","Cell RNA - ASC diff [nTPM]":"40.3","Cell RNA - ASC TERT1 [nTPM]":"46.0","Cell RNA - BEWO [nTPM]":"43.4","Cell RNA - BJ [nTPM]":"50.8","Cell RNA - BJ hTERT+ [nTPM]":"55.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"43.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"49.7","Cell RNA - CACO-2 [nTPM]":"18.8","Cell RNA - CAPAN-2 [nTPM]":"33.6","Cell RNA - Daudi [nTPM]":"73.5","Cell RNA - EFO-21 [nTPM]":"45.5","Cell RNA - fHDF\/TERT166 [nTPM]":"35.0","Cell RNA - GAMG [nTPM]":"41.7","Cell RNA - HaCaT [nTPM]":"36.4","Cell RNA - HAP1 [nTPM]":"47.0","Cell RNA - HBEC3-KT [nTPM]":"40.6","Cell RNA - HBF TERT88 [nTPM]":"61.0","Cell RNA - HDLM-2 [nTPM]":"29.4","Cell RNA - HEK 293 [nTPM]":"27.6","Cell RNA - HEL [nTPM]":"93.6","Cell RNA - HeLa [nTPM]":"28.6","Cell RNA - Hep G2 [nTPM]":"22.1","Cell RNA - HHSteC [nTPM]":"41.2","Cell RNA - HL-60 [nTPM]":"41.7","Cell RNA - HMC-1 [nTPM]":"32.5","Cell RNA - HSkMC [nTPM]":"24.9","Cell RNA - hTCEpi [nTPM]":"40.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"39.0","Cell RNA - hTERT-HME1 [nTPM]":"78.6","Cell RNA - hTERT-RPE1 [nTPM]":"40.3","Cell RNA - HUVEC TERT2 [nTPM]":"50.1","Cell RNA - JURKAT [nTPM]":"79.8","Cell RNA - K-562 [nTPM]":"67.9","Cell RNA - Karpas-707 [nTPM]":"47.4","Cell RNA - LHCN-M2 [nTPM]":"41.5","Cell RNA - MCF7 [nTPM]":"22.3","Cell RNA - MOLT-4 [nTPM]":"122.8","Cell RNA - NB-4 [nTPM]":"35.4","Cell RNA - NTERA-2 [nTPM]":"40.0","Cell RNA - OE19 [nTPM]":"48.0","Cell RNA - PC-3 [nTPM]":"16.4","Cell RNA - REH [nTPM]":"55.5","Cell RNA - RH-30 [nTPM]":"64.1","Cell RNA - RPMI-8226 [nTPM]":"23.4","Cell RNA - RPTEC TERT1 [nTPM]":"30.3","Cell RNA - RT4 [nTPM]":"47.3","Cell RNA - SCLC-21H [nTPM]":"33.0","Cell RNA - SH-SY5Y [nTPM]":"44.6","Cell RNA - SiHa [nTPM]":"41.4","Cell RNA - SK-BR-3 [nTPM]":"35.8","Cell RNA - SK-MEL-30 [nTPM]":"35.3","Cell RNA - SuSa [nTPM]":"37.5","Cell RNA - T-47d [nTPM]":"45.1","Cell RNA - THP-1 [nTPM]":"31.4","Cell RNA - TIME [nTPM]":"48.3","Cell RNA - U-138 MG [nTPM]":"44.5","Cell RNA - U-2 OS [nTPM]":"46.0","Cell RNA - U-2197 [nTPM]":"67.0","Cell RNA - U-251 MG [nTPM]":"30.3","Cell RNA - U-266\/70 [nTPM]":"41.9","Cell RNA - U-266\/84 [nTPM]":"53.8","Cell RNA - U-698 [nTPM]":"69.2","Cell RNA - U-87 MG [nTPM]":"37.6","Cell RNA - U-937 [nTPM]":"41.3","Cell RNA - WM-115 [nTPM]":"33.0","Blood RNA - basophil [nTPM]":"37.4","Blood RNA - classical monocyte [nTPM]":"11.8","Blood RNA - eosinophil [nTPM]":"21.9","Blood RNA - gdT-cell [nTPM]":"17.2","Blood RNA - intermediate monocyte [nTPM]":"5.6","Blood RNA - MAIT T-cell [nTPM]":"11.0","Blood RNA - memory B-cell [nTPM]":"43.1","Blood RNA - memory CD4 T-cell [nTPM]":"25.5","Blood RNA - memory CD8 T-cell [nTPM]":"15.5","Blood RNA - myeloid DC [nTPM]":"9.3","Blood RNA - naive B-cell [nTPM]":"60.7","Blood RNA - naive CD4 T-cell [nTPM]":"31.9","Blood RNA - naive CD8 T-cell [nTPM]":"13.7","Blood RNA - neutrophil [nTPM]":"57.9","Blood RNA - NK-cell [nTPM]":"19.6","Blood RNA - non-classical monocyte [nTPM]":"3.6","Blood RNA - plasmacytoid DC [nTPM]":"12.6","Blood RNA - T-reg [nTPM]":"43.4","Blood RNA - total PBMC [nTPM]":"7.3","Brain RNA - amygdala [nTPM]":"10.0","Brain RNA - basal ganglia [nTPM]":"13.7","Brain RNA - cerebellum [nTPM]":"28.4","Brain RNA - cerebral cortex [nTPM]":"20.5","Brain RNA - hippocampal formation [nTPM]":"12.8","Brain RNA - hypothalamus [nTPM]":"22.3","Brain RNA - medulla oblongata [nTPM]":"3.1","Brain RNA - midbrain [nTPM]":"4.8","Brain RNA - pons [nTPM]":"5.3","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"10.4","Brain RNA - white matter [nTPM]":"18.7","Single Cell Type RNA - Adipocytes [nTPM]":"75.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"67.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"57.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"57.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"73.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"69.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"30.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"51.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"101.6","Single Cell Type RNA - dendritic cells [nTPM]":"101.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"73.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"109.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"81.3","Single Cell Type RNA - Endothelial cells [nTPM]":"28.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"61.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"173.8","Single Cell Type RNA - Fibroblasts [nTPM]":"33.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"97.5","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"99.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"44.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"30.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"49.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"64.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"48.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"31.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"34.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"35.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"130.8","Single Cell Type RNA - T-cells [nTPM]":"55.6","Single Cell Type RNA - Theca cells [nTPM]":"81.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"NSDHL","Gene synonym":["H105e3","SDR31E1","XAP104"],"Ensembl":"ENSG00000147383","Gene description":"NAD(P) dependent steroid dehydrogenase-like","Uniprot":["Q15738"],"Chromosome":"X","Position":"152830967-152869729","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Ichthyosis","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"53.0","Hepatocytes":"55.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000248","HPA000571"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum","Lipid droplets"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Lipid droplets"],"Antibody RRID":{"HPA000248":"AB_1079507","HPA000571":"AB_1079506"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.65e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.04e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.09e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Tissue RNA - adipose tissue [nTPM]":"24.0","Tissue RNA - adrenal gland [nTPM]":"38.8","Tissue RNA - amygdala [nTPM]":"13.2","Tissue RNA - appendix [nTPM]":"10.2","Tissue RNA - basal ganglia [nTPM]":"12.6","Tissue RNA - bone marrow [nTPM]":"8.9","Tissue RNA - breast [nTPM]":"20.2","Tissue RNA - cerebellum [nTPM]":"14.2","Tissue RNA - cerebral cortex [nTPM]":"13.3","Tissue RNA - cervix [nTPM]":"20.3","Tissue RNA - choroid plexus [nTPM]":"13.7","Tissue RNA - colon [nTPM]":"13.9","Tissue RNA - duodenum [nTPM]":"17.6","Tissue RNA - endometrium 1 [nTPM]":"13.6","Tissue RNA - epididymis [nTPM]":"44.5","Tissue RNA - esophagus [nTPM]":"51.7","Tissue RNA - fallopian tube [nTPM]":"14.9","Tissue RNA - gallbladder [nTPM]":"7.9","Tissue RNA - heart muscle [nTPM]":"22.4","Tissue RNA - hippocampal formation [nTPM]":"13.7","Tissue RNA - hypothalamus [nTPM]":"14.3","Tissue RNA - kidney [nTPM]":"14.9","Tissue RNA - liver [nTPM]":"50.4","Tissue RNA - lung [nTPM]":"12.9","Tissue RNA - lymph node [nTPM]":"9.1","Tissue RNA - medulla oblongata [nTPM]":"16.8","Tissue RNA - midbrain [nTPM]":"15.4","Tissue RNA - ovary [nTPM]":"10.3","Tissue RNA - pancreas [nTPM]":"10.6","Tissue RNA - parathyroid gland [nTPM]":"12.9","Tissue RNA - pituitary gland [nTPM]":"8.8","Tissue RNA - placenta [nTPM]":"10.3","Tissue RNA - pons [nTPM]":"18.5","Tissue RNA - prostate [nTPM]":"14.8","Tissue RNA - rectum [nTPM]":"13.5","Tissue RNA - retina [nTPM]":"10.4","Tissue RNA - salivary gland [nTPM]":"16.7","Tissue RNA - seminal vesicle [nTPM]":"21.3","Tissue RNA - skeletal muscle [nTPM]":"10.1","Tissue RNA - skin 1 [nTPM]":"22.6","Tissue RNA - small intestine [nTPM]":"24.2","Tissue RNA - smooth muscle [nTPM]":"12.5","Tissue RNA - spinal cord [nTPM]":"13.4","Tissue RNA - spleen [nTPM]":"9.5","Tissue RNA - stomach 1 [nTPM]":"13.8","Tissue RNA - testis [nTPM]":"8.9","Tissue RNA - thalamus [nTPM]":"15.2","Tissue RNA - thymus [nTPM]":"9.9","Tissue RNA - thyroid gland [nTPM]":"13.3","Tissue RNA - tongue [nTPM]":"10.9","Tissue RNA - tonsil [nTPM]":"18.1","Tissue RNA - urinary bladder [nTPM]":"12.1","Tissue RNA - vagina [nTPM]":"24.1","Tissue RNA - white matter [nTPM]":"15.1","Cell RNA - A-431 [nTPM]":"135.6","Cell RNA - A549 [nTPM]":"48.9","Cell RNA - AF22 [nTPM]":"65.5","Cell RNA - AN3-CA [nTPM]":"33.8","Cell RNA - ASC diff [nTPM]":"54.9","Cell RNA - ASC TERT1 [nTPM]":"41.5","Cell RNA - BEWO [nTPM]":"36.2","Cell RNA - BJ [nTPM]":"26.3","Cell RNA - BJ hTERT+ [nTPM]":"35.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"46.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"59.3","Cell RNA - CACO-2 [nTPM]":"68.5","Cell RNA - CAPAN-2 [nTPM]":"71.7","Cell RNA - Daudi [nTPM]":"67.0","Cell RNA - EFO-21 [nTPM]":"86.0","Cell RNA - fHDF\/TERT166 [nTPM]":"35.9","Cell RNA - GAMG [nTPM]":"174.2","Cell RNA - HaCaT [nTPM]":"67.6","Cell RNA - HAP1 [nTPM]":"85.5","Cell RNA - HBEC3-KT [nTPM]":"122.1","Cell RNA - HBF TERT88 [nTPM]":"41.3","Cell RNA - HDLM-2 [nTPM]":"22.0","Cell RNA - HEK 293 [nTPM]":"49.5","Cell RNA - HEL [nTPM]":"27.9","Cell RNA - HeLa [nTPM]":"44.7","Cell RNA - Hep G2 [nTPM]":"70.3","Cell RNA - HHSteC [nTPM]":"39.8","Cell RNA - HL-60 [nTPM]":"27.6","Cell RNA - HMC-1 [nTPM]":"21.1","Cell RNA - HSkMC [nTPM]":"51.1","Cell RNA - hTCEpi [nTPM]":"46.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"92.2","Cell RNA - hTERT-HME1 [nTPM]":"23.0","Cell RNA - hTERT-RPE1 [nTPM]":"20.2","Cell RNA - HUVEC TERT2 [nTPM]":"44.2","Cell RNA - JURKAT [nTPM]":"28.7","Cell RNA - K-562 [nTPM]":"46.4","Cell RNA - Karpas-707 [nTPM]":"29.1","Cell RNA - LHCN-M2 [nTPM]":"36.1","Cell RNA - MCF7 [nTPM]":"60.1","Cell RNA - MOLT-4 [nTPM]":"27.3","Cell RNA - NB-4 [nTPM]":"35.8","Cell RNA - NTERA-2 [nTPM]":"26.0","Cell RNA - OE19 [nTPM]":"67.4","Cell RNA - PC-3 [nTPM]":"58.1","Cell RNA - REH [nTPM]":"19.9","Cell RNA - RH-30 [nTPM]":"47.4","Cell RNA - RPMI-8226 [nTPM]":"54.6","Cell RNA - RPTEC TERT1 [nTPM]":"98.9","Cell RNA - RT4 [nTPM]":"55.7","Cell RNA - SCLC-21H [nTPM]":"23.4","Cell RNA - SH-SY5Y [nTPM]":"26.5","Cell RNA - SiHa [nTPM]":"23.4","Cell RNA - SK-BR-3 [nTPM]":"34.6","Cell RNA - SK-MEL-30 [nTPM]":"28.4","Cell RNA - SuSa [nTPM]":"44.9","Cell RNA - T-47d [nTPM]":"23.1","Cell RNA - THP-1 [nTPM]":"35.0","Cell RNA - TIME [nTPM]":"38.7","Cell RNA - U-138 MG [nTPM]":"21.6","Cell RNA - U-2 OS [nTPM]":"35.4","Cell RNA - U-2197 [nTPM]":"52.3","Cell RNA - U-251 MG [nTPM]":"51.0","Cell RNA - U-266\/70 [nTPM]":"40.9","Cell RNA - U-266\/84 [nTPM]":"29.4","Cell RNA - U-698 [nTPM]":"114.9","Cell RNA - U-87 MG [nTPM]":"40.0","Cell RNA - U-937 [nTPM]":"42.4","Cell RNA - WM-115 [nTPM]":"20.8","Blood RNA - basophil [nTPM]":"21.0","Blood RNA - classical monocyte [nTPM]":"19.6","Blood RNA - eosinophil [nTPM]":"18.7","Blood RNA - gdT-cell [nTPM]":"16.3","Blood RNA - intermediate monocyte [nTPM]":"18.7","Blood RNA - MAIT T-cell [nTPM]":"16.4","Blood RNA - memory B-cell [nTPM]":"19.1","Blood RNA - memory CD4 T-cell [nTPM]":"16.1","Blood RNA - memory CD8 T-cell [nTPM]":"14.1","Blood RNA - myeloid DC [nTPM]":"19.4","Blood RNA - naive B-cell [nTPM]":"15.1","Blood RNA - naive CD4 T-cell [nTPM]":"11.6","Blood RNA - naive CD8 T-cell [nTPM]":"12.7","Blood RNA - neutrophil [nTPM]":"2.2","Blood RNA - NK-cell [nTPM]":"19.7","Blood RNA - non-classical monocyte [nTPM]":"14.2","Blood RNA - plasmacytoid DC [nTPM]":"17.4","Blood RNA - T-reg [nTPM]":"20.4","Blood RNA - total PBMC [nTPM]":"15.2","Brain RNA - amygdala [nTPM]":"13.2","Brain RNA - basal ganglia [nTPM]":"12.6","Brain RNA - cerebellum [nTPM]":"14.2","Brain RNA - cerebral cortex [nTPM]":"13.3","Brain RNA - hippocampal formation [nTPM]":"13.7","Brain RNA - hypothalamus [nTPM]":"14.3","Brain RNA - medulla oblongata [nTPM]":"16.8","Brain RNA - midbrain [nTPM]":"15.4","Brain RNA - pons [nTPM]":"18.5","Brain RNA - spinal cord [nTPM]":"13.4","Brain RNA - thalamus [nTPM]":"15.2","Brain RNA - white matter [nTPM]":"15.1","Single Cell Type RNA - Adipocytes [nTPM]":"7.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.7","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"6.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"53.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"4.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"29.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"21.5","Single Cell Type RNA - dendritic cells [nTPM]":"6.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"20.1","Single Cell Type RNA - Early spermatids [nTPM]":"13.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.6","Single Cell Type RNA - Endothelial cells [nTPM]":"9.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"13.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"20.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"22.0","Single Cell Type RNA - Fibroblasts [nTPM]":"9.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.5","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"14.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"55.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.6","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.2","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"8.7","Single Cell Type RNA - Langerhans cells [nTPM]":"9.6","Single Cell Type RNA - Late spermatids [nTPM]":"8.0","Single Cell Type RNA - Leydig cells [nTPM]":"8.4","Single Cell Type RNA - Macrophages [nTPM]":"7.9","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"11.0","Single Cell Type RNA - Muller glia cells [nTPM]":"10.6","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.4","Single Cell Type RNA - Paneth cells [nTPM]":"11.9","Single Cell Type RNA - Peritubular cells [nTPM]":"9.1","Single Cell Type RNA - Plasma cells [nTPM]":"11.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"25.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"25.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.5","Single Cell Type RNA - Spermatocytes [nTPM]":"3.7","Single Cell Type RNA - Spermatogonia [nTPM]":"7.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"18.6","Single Cell Type RNA - T-cells [nTPM]":"5.3","Single Cell Type RNA - Theca cells [nTPM]":"25.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.2","Single Cell Type RNA - Urothelial cells [nTPM]":"16.4"},{"Gene":"NSUN2","Gene synonym":["FLJ20303","Misu","MRT5","TRM4"],"Ensembl":"ENSG00000037474","Gene description":"NOP2\/Sun RNA methyltransferase 2","Uniprot":["Q08J23"],"Chromosome":"5","Position":"6599239-6633291","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Differentiation","Mitosis","Spermatogenesis","tRNA processing"],"Molecular function":["Methyltransferase","RNA-binding","Transferase","tRNA-binding"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037896"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA037896":"AB_10670532"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.69e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Tissue RNA - adipose tissue [nTPM]":"21.6","Tissue RNA - adrenal gland [nTPM]":"16.0","Tissue RNA - amygdala [nTPM]":"10.4","Tissue RNA - appendix [nTPM]":"29.1","Tissue RNA - basal ganglia [nTPM]":"10.9","Tissue RNA - bone marrow [nTPM]":"28.2","Tissue RNA - breast [nTPM]":"38.6","Tissue RNA - cerebellum [nTPM]":"11.3","Tissue RNA - cerebral cortex [nTPM]":"13.4","Tissue RNA - cervix [nTPM]":"16.2","Tissue RNA - choroid plexus [nTPM]":"12.0","Tissue RNA - colon [nTPM]":"24.7","Tissue RNA - duodenum [nTPM]":"20.8","Tissue RNA - endometrium 1 [nTPM]":"18.2","Tissue RNA - epididymis [nTPM]":"19.5","Tissue RNA - esophagus [nTPM]":"24.1","Tissue RNA - fallopian tube [nTPM]":"17.7","Tissue RNA - gallbladder [nTPM]":"17.8","Tissue RNA - heart muscle [nTPM]":"23.0","Tissue RNA - hippocampal formation [nTPM]":"10.8","Tissue RNA - hypothalamus [nTPM]":"11.3","Tissue RNA - kidney [nTPM]":"16.4","Tissue RNA - liver [nTPM]":"36.7","Tissue RNA - lung [nTPM]":"19.5","Tissue RNA - lymph node [nTPM]":"34.3","Tissue RNA - medulla oblongata [nTPM]":"11.2","Tissue RNA - midbrain [nTPM]":"10.6","Tissue RNA - ovary [nTPM]":"18.0","Tissue RNA - pancreas [nTPM]":"20.0","Tissue RNA - parathyroid gland [nTPM]":"24.9","Tissue RNA - pituitary gland [nTPM]":"11.5","Tissue RNA - placenta [nTPM]":"19.8","Tissue RNA - pons [nTPM]":"11.2","Tissue RNA - prostate [nTPM]":"20.7","Tissue RNA - rectum [nTPM]":"27.7","Tissue RNA - retina [nTPM]":"10.9","Tissue RNA - salivary gland [nTPM]":"17.9","Tissue RNA - seminal vesicle [nTPM]":"17.0","Tissue RNA - skeletal muscle [nTPM]":"39.0","Tissue RNA - skin 1 [nTPM]":"22.7","Tissue RNA - small intestine [nTPM]":"20.4","Tissue RNA - smooth muscle [nTPM]":"22.4","Tissue RNA - spinal cord [nTPM]":"10.4","Tissue RNA - spleen [nTPM]":"23.0","Tissue RNA - stomach 1 [nTPM]":"21.4","Tissue RNA - testis [nTPM]":"18.9","Tissue RNA - thalamus [nTPM]":"11.8","Tissue RNA - thymus [nTPM]":"26.5","Tissue RNA - thyroid gland [nTPM]":"18.0","Tissue RNA - tongue [nTPM]":"30.2","Tissue RNA - tonsil [nTPM]":"36.8","Tissue RNA - urinary bladder [nTPM]":"29.3","Tissue RNA - vagina [nTPM]":"15.0","Tissue RNA - white matter [nTPM]":"13.2","Cell RNA - A-431 [nTPM]":"97.6","Cell RNA - A549 [nTPM]":"85.8","Cell RNA - AF22 [nTPM]":"49.9","Cell RNA - AN3-CA [nTPM]":"45.4","Cell RNA - ASC diff [nTPM]":"31.7","Cell RNA - ASC TERT1 [nTPM]":"36.1","Cell RNA - BEWO [nTPM]":"112.9","Cell RNA - BJ [nTPM]":"72.5","Cell RNA - BJ hTERT+ [nTPM]":"48.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"84.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"71.5","Cell RNA - CACO-2 [nTPM]":"113.0","Cell RNA - CAPAN-2 [nTPM]":"75.6","Cell RNA - Daudi [nTPM]":"170.6","Cell RNA - EFO-21 [nTPM]":"74.0","Cell RNA - fHDF\/TERT166 [nTPM]":"63.8","Cell RNA - GAMG [nTPM]":"101.6","Cell RNA - HaCaT [nTPM]":"70.7","Cell RNA - HAP1 [nTPM]":"102.1","Cell RNA - HBEC3-KT [nTPM]":"90.6","Cell RNA - HBF TERT88 [nTPM]":"114.6","Cell RNA - HDLM-2 [nTPM]":"115.1","Cell RNA - HEK 293 [nTPM]":"73.4","Cell RNA - HEL [nTPM]":"100.8","Cell RNA - HeLa [nTPM]":"199.0","Cell RNA - Hep G2 [nTPM]":"67.0","Cell RNA - HHSteC [nTPM]":"44.8","Cell RNA - HL-60 [nTPM]":"176.8","Cell RNA - HMC-1 [nTPM]":"77.4","Cell RNA - HSkMC [nTPM]":"40.2","Cell RNA - hTCEpi [nTPM]":"67.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"91.8","Cell RNA - hTERT-HME1 [nTPM]":"80.5","Cell RNA - hTERT-RPE1 [nTPM]":"33.6","Cell RNA - HUVEC TERT2 [nTPM]":"60.6","Cell RNA - JURKAT [nTPM]":"70.3","Cell RNA - K-562 [nTPM]":"132.3","Cell RNA - Karpas-707 [nTPM]":"66.3","Cell RNA - LHCN-M2 [nTPM]":"79.9","Cell RNA - MCF7 [nTPM]":"71.1","Cell RNA - MOLT-4 [nTPM]":"93.2","Cell RNA - NB-4 [nTPM]":"89.3","Cell RNA - NTERA-2 [nTPM]":"80.0","Cell RNA - OE19 [nTPM]":"69.3","Cell RNA - PC-3 [nTPM]":"101.3","Cell RNA - REH [nTPM]":"121.1","Cell RNA - RH-30 [nTPM]":"50.5","Cell RNA - RPMI-8226 [nTPM]":"54.7","Cell RNA - RPTEC TERT1 [nTPM]":"61.7","Cell RNA - RT4 [nTPM]":"112.1","Cell RNA - SCLC-21H [nTPM]":"45.8","Cell RNA - SH-SY5Y [nTPM]":"65.4","Cell RNA - SiHa [nTPM]":"184.4","Cell RNA - SK-BR-3 [nTPM]":"101.2","Cell RNA - SK-MEL-30 [nTPM]":"79.1","Cell RNA - SuSa [nTPM]":"65.0","Cell RNA - T-47d [nTPM]":"85.0","Cell RNA - THP-1 [nTPM]":"84.2","Cell RNA - TIME [nTPM]":"66.6","Cell RNA - U-138 MG [nTPM]":"66.8","Cell RNA - U-2 OS [nTPM]":"82.0","Cell RNA - U-2197 [nTPM]":"68.4","Cell RNA - U-251 MG [nTPM]":"111.1","Cell RNA - U-266\/70 [nTPM]":"51.2","Cell RNA - U-266\/84 [nTPM]":"100.1","Cell RNA - U-698 [nTPM]":"159.9","Cell RNA - U-87 MG [nTPM]":"52.9","Cell RNA - U-937 [nTPM]":"143.9","Cell RNA - WM-115 [nTPM]":"77.6","Blood RNA - basophil [nTPM]":"16.2","Blood RNA - classical monocyte [nTPM]":"18.6","Blood RNA - eosinophil [nTPM]":"21.2","Blood RNA - gdT-cell [nTPM]":"21.1","Blood RNA - intermediate monocyte [nTPM]":"22.4","Blood RNA - MAIT T-cell [nTPM]":"27.9","Blood RNA - memory B-cell [nTPM]":"22.4","Blood RNA - memory CD4 T-cell [nTPM]":"22.1","Blood RNA - memory CD8 T-cell [nTPM]":"25.0","Blood RNA - myeloid DC [nTPM]":"21.5","Blood RNA - naive B-cell [nTPM]":"20.6","Blood RNA - naive CD4 T-cell [nTPM]":"23.2","Blood RNA - naive CD8 T-cell [nTPM]":"23.5","Blood RNA - neutrophil [nTPM]":"3.9","Blood RNA - NK-cell [nTPM]":"24.4","Blood RNA - non-classical monocyte [nTPM]":"21.2","Blood RNA - plasmacytoid DC [nTPM]":"20.2","Blood RNA - T-reg [nTPM]":"17.0","Blood RNA - total PBMC [nTPM]":"17.0","Brain RNA - amygdala [nTPM]":"10.4","Brain RNA - basal ganglia [nTPM]":"10.9","Brain RNA - cerebellum [nTPM]":"11.3","Brain RNA - cerebral cortex [nTPM]":"13.4","Brain RNA - hippocampal formation [nTPM]":"10.8","Brain RNA - hypothalamus [nTPM]":"11.3","Brain RNA - medulla oblongata [nTPM]":"11.2","Brain RNA - midbrain [nTPM]":"10.6","Brain RNA - pons [nTPM]":"11.2","Brain RNA - spinal cord [nTPM]":"10.4","Brain RNA - thalamus [nTPM]":"11.8","Brain RNA - white matter [nTPM]":"13.2","Single Cell Type RNA - Adipocytes [nTPM]":"13.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.6","Single Cell Type RNA - Astrocytes [nTPM]":"27.7","Single Cell Type RNA - B-cells [nTPM]":"26.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"37.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.6","Single Cell Type RNA - Bipolar cells [nTPM]":"6.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"30.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.1","Single Cell Type RNA - dendritic cells [nTPM]":"17.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"19.6","Single Cell Type RNA - Early spermatids [nTPM]":"3.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.9","Single Cell Type RNA - Endothelial cells [nTPM]":"16.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.9","Single Cell Type RNA - Erythroid cells [nTPM]":"22.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"37.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.2","Single Cell Type RNA - Fibroblasts [nTPM]":"14.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.1","Single Cell Type RNA - granulocytes [nTPM]":"20.8","Single Cell Type RNA - Granulosa cells [nTPM]":"17.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.0","Single Cell Type RNA - Hepatocytes [nTPM]":"33.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.4","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"30.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.5","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"18.5","Single Cell Type RNA - Langerhans cells [nTPM]":"21.1","Single Cell Type RNA - Late spermatids [nTPM]":"2.9","Single Cell Type RNA - Leydig cells [nTPM]":"13.1","Single Cell Type RNA - Macrophages [nTPM]":"16.4","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"21.9","Single Cell Type RNA - Muller glia cells [nTPM]":"7.2","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"24.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"45.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"24.8","Single Cell Type RNA - Paneth cells [nTPM]":"14.8","Single Cell Type RNA - Peritubular cells [nTPM]":"14.3","Single Cell Type RNA - Plasma cells [nTPM]":"23.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.4","Single Cell Type RNA - Spermatocytes [nTPM]":"14.9","Single Cell Type RNA - Spermatogonia [nTPM]":"17.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"30.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"30.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.1","Single Cell Type RNA - T-cells [nTPM]":"20.7","Single Cell Type RNA - Theca cells [nTPM]":"17.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.8","Single Cell Type RNA - Urothelial cells [nTPM]":"17.0"},{"Gene":"NT5C2","Gene synonym":["cN-II","GMP","NT5B","PNT5","SPG45","SPG65"],"Ensembl":"ENSG00000076685","Gene description":"5'-nucleotidase, cytosolic II","Uniprot":["P49902"],"Chromosome":"10","Position":"103087185-103277605","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Nucleotide metabolism"],"Molecular function":["Allosteric enzyme","Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"141.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003751"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA003751":"AB_1854664"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Tissue RNA - adipose tissue [nTPM]":"24.6","Tissue RNA - adrenal gland [nTPM]":"27.0","Tissue RNA - amygdala [nTPM]":"25.0","Tissue RNA - appendix [nTPM]":"19.0","Tissue RNA - basal ganglia [nTPM]":"27.2","Tissue RNA - bone marrow [nTPM]":"29.7","Tissue RNA - breast [nTPM]":"23.0","Tissue RNA - cerebellum [nTPM]":"27.3","Tissue RNA - cerebral cortex [nTPM]":"28.5","Tissue RNA - cervix [nTPM]":"37.6","Tissue RNA - choroid plexus [nTPM]":"36.8","Tissue RNA - colon [nTPM]":"27.3","Tissue RNA - duodenum [nTPM]":"9.9","Tissue RNA - endometrium 1 [nTPM]":"18.8","Tissue RNA - epididymis [nTPM]":"17.3","Tissue RNA - esophagus [nTPM]":"67.1","Tissue RNA - fallopian tube [nTPM]":"26.5","Tissue RNA - gallbladder [nTPM]":"16.4","Tissue RNA - heart muscle [nTPM]":"28.5","Tissue RNA - hippocampal formation [nTPM]":"25.2","Tissue RNA - hypothalamus [nTPM]":"28.8","Tissue RNA - kidney [nTPM]":"32.5","Tissue RNA - liver [nTPM]":"27.8","Tissue RNA - lung [nTPM]":"30.8","Tissue RNA - lymph node [nTPM]":"18.3","Tissue RNA - medulla oblongata [nTPM]":"26.9","Tissue RNA - midbrain [nTPM]":"29.5","Tissue RNA - ovary [nTPM]":"32.4","Tissue RNA - pancreas [nTPM]":"22.0","Tissue RNA - parathyroid gland [nTPM]":"21.7","Tissue RNA - pituitary gland [nTPM]":"34.0","Tissue RNA - placenta [nTPM]":"17.9","Tissue RNA - pons [nTPM]":"27.2","Tissue RNA - prostate [nTPM]":"32.4","Tissue RNA - rectum [nTPM]":"16.7","Tissue RNA - retina [nTPM]":"47.3","Tissue RNA - salivary gland [nTPM]":"46.4","Tissue RNA - seminal vesicle [nTPM]":"18.4","Tissue RNA - skeletal muscle [nTPM]":"51.6","Tissue RNA - skin 1 [nTPM]":"19.9","Tissue RNA - small intestine [nTPM]":"20.4","Tissue RNA - smooth muscle [nTPM]":"13.4","Tissue RNA - spinal cord [nTPM]":"26.4","Tissue RNA - spleen [nTPM]":"32.8","Tissue RNA - stomach 1 [nTPM]":"22.3","Tissue RNA - testis [nTPM]":"30.8","Tissue RNA - thalamus [nTPM]":"27.2","Tissue RNA - thymus [nTPM]":"28.6","Tissue RNA - thyroid gland [nTPM]":"55.4","Tissue RNA - tongue [nTPM]":"18.1","Tissue RNA - tonsil [nTPM]":"24.5","Tissue RNA - urinary bladder [nTPM]":"33.3","Tissue RNA - vagina [nTPM]":"42.7","Tissue RNA - white matter [nTPM]":"28.6","Cell RNA - A-431 [nTPM]":"148.4","Cell RNA - A549 [nTPM]":"52.5","Cell RNA - AF22 [nTPM]":"32.6","Cell RNA - AN3-CA [nTPM]":"67.5","Cell RNA - ASC diff [nTPM]":"27.2","Cell RNA - ASC TERT1 [nTPM]":"33.2","Cell RNA - BEWO [nTPM]":"18.2","Cell RNA - BJ [nTPM]":"66.0","Cell RNA - BJ hTERT+ [nTPM]":"64.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"29.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"32.4","Cell RNA - CACO-2 [nTPM]":"34.6","Cell RNA - CAPAN-2 [nTPM]":"91.7","Cell RNA - Daudi [nTPM]":"49.2","Cell RNA - EFO-21 [nTPM]":"47.7","Cell RNA - fHDF\/TERT166 [nTPM]":"45.6","Cell RNA - GAMG [nTPM]":"27.6","Cell RNA - HaCaT [nTPM]":"62.8","Cell RNA - HAP1 [nTPM]":"23.4","Cell RNA - HBEC3-KT [nTPM]":"33.8","Cell RNA - HBF TERT88 [nTPM]":"38.3","Cell RNA - HDLM-2 [nTPM]":"40.3","Cell RNA - HEK 293 [nTPM]":"21.6","Cell RNA - HEL [nTPM]":"38.7","Cell RNA - HeLa [nTPM]":"21.1","Cell RNA - Hep G2 [nTPM]":"39.6","Cell RNA - HHSteC [nTPM]":"48.5","Cell RNA - HL-60 [nTPM]":"64.2","Cell RNA - HMC-1 [nTPM]":"21.0","Cell RNA - HSkMC [nTPM]":"50.4","Cell RNA - hTCEpi [nTPM]":"34.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"28.0","Cell RNA - hTERT-HME1 [nTPM]":"24.8","Cell RNA - hTERT-RPE1 [nTPM]":"57.5","Cell RNA - HUVEC TERT2 [nTPM]":"25.6","Cell RNA - JURKAT [nTPM]":"19.4","Cell RNA - K-562 [nTPM]":"29.4","Cell RNA - Karpas-707 [nTPM]":"36.4","Cell RNA - LHCN-M2 [nTPM]":"54.5","Cell RNA - MCF7 [nTPM]":"73.8","Cell RNA - MOLT-4 [nTPM]":"53.7","Cell RNA - NB-4 [nTPM]":"64.6","Cell RNA - NTERA-2 [nTPM]":"34.6","Cell RNA - OE19 [nTPM]":"43.2","Cell RNA - PC-3 [nTPM]":"68.6","Cell RNA - REH [nTPM]":"102.6","Cell RNA - RH-30 [nTPM]":"30.0","Cell RNA - RPMI-8226 [nTPM]":"19.6","Cell RNA - RPTEC TERT1 [nTPM]":"43.3","Cell RNA - RT4 [nTPM]":"72.5","Cell RNA - SCLC-21H [nTPM]":"10.0","Cell RNA - SH-SY5Y [nTPM]":"24.9","Cell RNA - SiHa [nTPM]":"35.8","Cell RNA - SK-BR-3 [nTPM]":"25.9","Cell RNA - SK-MEL-30 [nTPM]":"50.3","Cell RNA - SuSa [nTPM]":"33.7","Cell RNA - T-47d [nTPM]":"39.2","Cell RNA - THP-1 [nTPM]":"38.1","Cell RNA - TIME [nTPM]":"30.5","Cell RNA - U-138 MG [nTPM]":"20.5","Cell RNA - U-2 OS [nTPM]":"24.8","Cell RNA - U-2197 [nTPM]":"39.7","Cell RNA - U-251 MG [nTPM]":"51.7","Cell RNA - U-266\/70 [nTPM]":"32.9","Cell RNA - U-266\/84 [nTPM]":"71.6","Cell RNA - U-698 [nTPM]":"85.5","Cell RNA - U-87 MG [nTPM]":"23.9","Cell RNA - U-937 [nTPM]":"64.6","Cell RNA - WM-115 [nTPM]":"7.8","Blood RNA - basophil [nTPM]":"29.5","Blood RNA - classical monocyte [nTPM]":"16.5","Blood RNA - eosinophil [nTPM]":"31.3","Blood RNA - gdT-cell [nTPM]":"10.0","Blood RNA - intermediate monocyte [nTPM]":"18.8","Blood RNA - MAIT T-cell [nTPM]":"10.3","Blood RNA - memory B-cell [nTPM]":"8.9","Blood RNA - memory CD4 T-cell [nTPM]":"8.4","Blood RNA - memory CD8 T-cell [nTPM]":"8.7","Blood RNA - myeloid DC [nTPM]":"14.7","Blood RNA - naive B-cell [nTPM]":"5.2","Blood RNA - naive CD4 T-cell [nTPM]":"6.7","Blood RNA - naive CD8 T-cell [nTPM]":"8.0","Blood RNA - neutrophil [nTPM]":"27.4","Blood RNA - NK-cell [nTPM]":"14.4","Blood RNA - non-classical monocyte [nTPM]":"23.0","Blood RNA - plasmacytoid DC [nTPM]":"9.6","Blood RNA - T-reg [nTPM]":"9.3","Blood RNA - total PBMC [nTPM]":"10.5","Brain RNA - amygdala [nTPM]":"25.0","Brain RNA - basal ganglia [nTPM]":"27.2","Brain RNA - cerebellum [nTPM]":"27.3","Brain RNA - cerebral cortex [nTPM]":"28.5","Brain RNA - hippocampal formation [nTPM]":"25.2","Brain RNA - hypothalamus [nTPM]":"28.8","Brain RNA - medulla oblongata [nTPM]":"26.9","Brain RNA - midbrain [nTPM]":"29.5","Brain RNA - pons [nTPM]":"27.2","Brain RNA - spinal cord [nTPM]":"26.4","Brain RNA - thalamus [nTPM]":"27.2","Brain RNA - white matter [nTPM]":"28.6","Single Cell Type RNA - Adipocytes [nTPM]":"16.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"83.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"34.9","Single Cell Type RNA - Astrocytes [nTPM]":"141.7","Single Cell Type RNA - B-cells [nTPM]":"17.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"29.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"26.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"24.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"60.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.4","Single Cell Type RNA - dendritic cells [nTPM]":"23.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"48.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"28.5","Single Cell Type RNA - Early spermatids [nTPM]":"103.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"29.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.1","Single Cell Type RNA - Endothelial cells [nTPM]":"19.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.5","Single Cell Type RNA - Erythroid cells [nTPM]":"12.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"79.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.7","Single Cell Type RNA - Fibroblasts [nTPM]":"17.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"25.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"46.2","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"18.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.9","Single Cell Type RNA - Hepatocytes [nTPM]":"17.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.9","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"83.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.6","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"29.8","Single Cell Type RNA - Langerhans cells [nTPM]":"14.2","Single Cell Type RNA - Late spermatids [nTPM]":"61.9","Single Cell Type RNA - Leydig cells [nTPM]":"24.8","Single Cell Type RNA - Macrophages [nTPM]":"27.1","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"78.7","Single Cell Type RNA - monocytes [nTPM]":"25.9","Single Cell Type RNA - Muller glia cells [nTPM]":"85.5","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"70.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"107.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"57.9","Single Cell Type RNA - Paneth cells [nTPM]":"23.1","Single Cell Type RNA - Peritubular cells [nTPM]":"13.5","Single Cell Type RNA - Plasma cells [nTPM]":"21.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"35.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"44.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"59.1","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.7","Single Cell Type RNA - Spermatocytes [nTPM]":"25.3","Single Cell Type RNA - Spermatogonia [nTPM]":"20.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"35.0","Single Cell Type RNA - T-cells [nTPM]":"16.6","Single Cell Type RNA - Theca cells [nTPM]":"15.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.0","Single Cell Type RNA - Urothelial cells [nTPM]":"80.5"},{"Gene":"NT5C3A","Gene synonym":["cN-III","hUMP1","NT5C3","p36","P5'N-1","PN-I","POMP","PSN1","UMPH","UMPH1"],"Ensembl":"ENSG00000122643","Gene description":"5'-nucleotidase, cytosolic IIIA","Uniprot":["Q9H0P0"],"Chromosome":"7","Position":"33014114-33062797","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Nucleotide metabolism"],"Molecular function":["Hydrolase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"87.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"191.0","Paneth cells":"186.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010520","HPA010630","HPA029058"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies","Endoplasmic reticulum","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"10000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 51: Myeloid cells - Hemostasis","Subcellular main location":["Endoplasmic reticulum","Cytosol"],"Subcellular additional location":["Nucleoplasm","Nuclear bodies"],"Antibody RRID":{"HPA010520":null,"HPA010630":"AB_2668319","HPA029058":"AB_10601380"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.42e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.70e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-3"},"Tissue RNA - adipose tissue [nTPM]":"12.4","Tissue RNA - adrenal gland [nTPM]":"14.3","Tissue RNA - amygdala [nTPM]":"11.4","Tissue RNA - appendix [nTPM]":"26.1","Tissue RNA - basal ganglia [nTPM]":"11.4","Tissue RNA - bone marrow [nTPM]":"32.6","Tissue RNA - breast [nTPM]":"21.3","Tissue RNA - cerebellum [nTPM]":"15.2","Tissue RNA - cerebral cortex [nTPM]":"15.6","Tissue RNA - cervix [nTPM]":"12.6","Tissue RNA - choroid plexus [nTPM]":"10.8","Tissue RNA - colon [nTPM]":"51.9","Tissue RNA - duodenum [nTPM]":"40.0","Tissue RNA - endometrium 1 [nTPM]":"16.9","Tissue RNA - epididymis [nTPM]":"14.3","Tissue RNA - esophagus [nTPM]":"18.6","Tissue RNA - fallopian tube [nTPM]":"15.9","Tissue RNA - gallbladder [nTPM]":"23.4","Tissue RNA - heart muscle [nTPM]":"16.6","Tissue RNA - hippocampal formation [nTPM]":"11.5","Tissue RNA - hypothalamus [nTPM]":"11.5","Tissue RNA - kidney [nTPM]":"22.4","Tissue RNA - liver [nTPM]":"11.8","Tissue RNA - lung [nTPM]":"17.6","Tissue RNA - lymph node [nTPM]":"30.8","Tissue RNA - medulla oblongata [nTPM]":"11.1","Tissue RNA - midbrain [nTPM]":"11.8","Tissue RNA - ovary [nTPM]":"13.4","Tissue RNA - pancreas [nTPM]":"21.4","Tissue RNA - parathyroid gland [nTPM]":"9.7","Tissue RNA - pituitary gland [nTPM]":"7.5","Tissue RNA - placenta [nTPM]":"16.3","Tissue RNA - pons [nTPM]":"11.5","Tissue RNA - prostate [nTPM]":"12.3","Tissue RNA - rectum [nTPM]":"51.0","Tissue RNA - retina [nTPM]":"20.4","Tissue RNA - salivary gland [nTPM]":"9.7","Tissue RNA - seminal vesicle [nTPM]":"10.0","Tissue RNA - skeletal muscle [nTPM]":"87.4","Tissue RNA - skin 1 [nTPM]":"28.7","Tissue RNA - small intestine [nTPM]":"37.3","Tissue RNA - smooth muscle [nTPM]":"13.2","Tissue RNA - spinal cord [nTPM]":"12.7","Tissue RNA - spleen [nTPM]":"22.9","Tissue RNA - stomach 1 [nTPM]":"27.0","Tissue RNA - testis [nTPM]":"9.5","Tissue RNA - thalamus [nTPM]":"12.0","Tissue RNA - thymus [nTPM]":"22.5","Tissue RNA - thyroid gland [nTPM]":"17.1","Tissue RNA - tongue [nTPM]":"51.0","Tissue RNA - tonsil [nTPM]":"45.8","Tissue RNA - urinary bladder [nTPM]":"23.8","Tissue RNA - vagina [nTPM]":"14.4","Tissue RNA - white matter [nTPM]":"13.1","Cell RNA - A-431 [nTPM]":"42.2","Cell RNA - A549 [nTPM]":"27.6","Cell RNA - AF22 [nTPM]":"25.2","Cell RNA - AN3-CA [nTPM]":"29.6","Cell RNA - ASC diff [nTPM]":"21.2","Cell RNA - ASC TERT1 [nTPM]":"16.1","Cell RNA - BEWO [nTPM]":"20.3","Cell RNA - BJ [nTPM]":"44.8","Cell RNA - BJ hTERT+ [nTPM]":"30.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"29.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"38.9","Cell RNA - CACO-2 [nTPM]":"19.9","Cell RNA - CAPAN-2 [nTPM]":"115.1","Cell RNA - Daudi [nTPM]":"100.4","Cell RNA - EFO-21 [nTPM]":"27.7","Cell RNA - fHDF\/TERT166 [nTPM]":"29.6","Cell RNA - GAMG [nTPM]":"48.3","Cell RNA - HaCaT [nTPM]":"63.8","Cell RNA - HAP1 [nTPM]":"28.3","Cell RNA - HBEC3-KT [nTPM]":"30.8","Cell RNA - HBF TERT88 [nTPM]":"40.4","Cell RNA - HDLM-2 [nTPM]":"16.2","Cell RNA - HEK 293 [nTPM]":"36.2","Cell RNA - HEL [nTPM]":"54.7","Cell RNA - HeLa [nTPM]":"36.5","Cell RNA - Hep G2 [nTPM]":"28.7","Cell RNA - HHSteC [nTPM]":"23.3","Cell RNA - HL-60 [nTPM]":"55.6","Cell RNA - HMC-1 [nTPM]":"36.9","Cell RNA - HSkMC [nTPM]":"21.7","Cell RNA - hTCEpi [nTPM]":"23.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"35.9","Cell RNA - hTERT-HME1 [nTPM]":"63.0","Cell RNA - hTERT-RPE1 [nTPM]":"16.4","Cell RNA - HUVEC TERT2 [nTPM]":"22.2","Cell RNA - JURKAT [nTPM]":"33.2","Cell RNA - K-562 [nTPM]":"43.3","Cell RNA - Karpas-707 [nTPM]":"24.8","Cell RNA - LHCN-M2 [nTPM]":"37.3","Cell RNA - MCF7 [nTPM]":"29.9","Cell RNA - MOLT-4 [nTPM]":"25.0","Cell RNA - NB-4 [nTPM]":"87.8","Cell RNA - NTERA-2 [nTPM]":"27.8","Cell RNA - OE19 [nTPM]":"47.1","Cell RNA - PC-3 [nTPM]":"31.2","Cell RNA - REH [nTPM]":"25.9","Cell RNA - RH-30 [nTPM]":"22.9","Cell RNA - RPMI-8226 [nTPM]":"60.0","Cell RNA - RPTEC TERT1 [nTPM]":"87.8","Cell RNA - RT4 [nTPM]":"39.8","Cell RNA - SCLC-21H [nTPM]":"28.1","Cell RNA - SH-SY5Y [nTPM]":"37.0","Cell RNA - SiHa [nTPM]":"31.1","Cell RNA - SK-BR-3 [nTPM]":"52.4","Cell RNA - SK-MEL-30 [nTPM]":"66.6","Cell RNA - SuSa [nTPM]":"24.5","Cell RNA - T-47d [nTPM]":"35.2","Cell RNA - THP-1 [nTPM]":"33.5","Cell RNA - TIME [nTPM]":"19.8","Cell RNA - U-138 MG [nTPM]":"25.1","Cell RNA - U-2 OS [nTPM]":"20.9","Cell RNA - U-2197 [nTPM]":"42.6","Cell RNA - U-251 MG [nTPM]":"55.7","Cell RNA - U-266\/70 [nTPM]":"50.6","Cell RNA - U-266\/84 [nTPM]":"69.0","Cell RNA - U-698 [nTPM]":"54.8","Cell RNA - U-87 MG [nTPM]":"20.6","Cell RNA - U-937 [nTPM]":"34.9","Cell RNA - WM-115 [nTPM]":"42.5","Blood RNA - basophil [nTPM]":"112.5","Blood RNA - classical monocyte [nTPM]":"25.9","Blood RNA - eosinophil [nTPM]":"82.5","Blood RNA - gdT-cell [nTPM]":"26.6","Blood RNA - intermediate monocyte [nTPM]":"32.7","Blood RNA - MAIT T-cell [nTPM]":"30.6","Blood RNA - memory B-cell [nTPM]":"64.0","Blood RNA - memory CD4 T-cell [nTPM]":"34.2","Blood RNA - memory CD8 T-cell [nTPM]":"30.8","Blood RNA - myeloid DC [nTPM]":"22.1","Blood RNA - naive B-cell [nTPM]":"63.6","Blood RNA - naive CD4 T-cell [nTPM]":"34.5","Blood RNA - naive CD8 T-cell [nTPM]":"29.1","Blood RNA - neutrophil [nTPM]":"103.8","Blood RNA - NK-cell [nTPM]":"28.2","Blood RNA - non-classical monocyte [nTPM]":"39.2","Blood RNA - plasmacytoid DC [nTPM]":"20.6","Blood RNA - T-reg [nTPM]":"56.2","Blood RNA - total PBMC [nTPM]":"37.9","Brain RNA - amygdala [nTPM]":"11.4","Brain RNA - basal ganglia [nTPM]":"11.4","Brain RNA - cerebellum [nTPM]":"15.2","Brain RNA - cerebral cortex [nTPM]":"15.6","Brain RNA - hippocampal formation [nTPM]":"11.5","Brain RNA - hypothalamus [nTPM]":"11.5","Brain RNA - medulla oblongata [nTPM]":"11.1","Brain RNA - midbrain [nTPM]":"11.8","Brain RNA - pons [nTPM]":"11.5","Brain RNA - spinal cord [nTPM]":"12.7","Brain RNA - thalamus [nTPM]":"12.0","Brain RNA - white matter [nTPM]":"13.1","Single Cell Type RNA - Adipocytes [nTPM]":"39.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.7","Single Cell Type RNA - Astrocytes [nTPM]":"30.7","Single Cell Type RNA - B-cells [nTPM]":"85.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"46.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"40.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"85.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"47.8","Single Cell Type RNA - Bipolar cells [nTPM]":"23.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"40.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"36.9","Single Cell Type RNA - dendritic cells [nTPM]":"42.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"191.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"29.4","Single Cell Type RNA - Ductal cells [nTPM]":"34.4","Single Cell Type RNA - Early spermatids [nTPM]":"5.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"40.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.0","Single Cell Type RNA - Endothelial cells [nTPM]":"40.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"119.6","Single Cell Type RNA - Erythroid cells [nTPM]":"127.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"45.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"79.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"31.6","Single Cell Type RNA - Fibroblasts [nTPM]":"35.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"42.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.4","Single Cell Type RNA - granulocytes [nTPM]":"17.7","Single Cell Type RNA - Granulosa cells [nTPM]":"38.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"30.0","Single Cell Type RNA - Hepatocytes [nTPM]":"18.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.0","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"49.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"98.9","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"31.2","Single Cell Type RNA - Langerhans cells [nTPM]":"23.5","Single Cell Type RNA - Late spermatids [nTPM]":"5.0","Single Cell Type RNA - Leydig cells [nTPM]":"33.8","Single Cell Type RNA - Macrophages [nTPM]":"111.4","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"29.0","Single Cell Type RNA - monocytes [nTPM]":"37.0","Single Cell Type RNA - Muller glia cells [nTPM]":"23.4","Single Cell Type RNA - NK-cells [nTPM]":"55.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"48.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"52.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"48.3","Single Cell Type RNA - Paneth cells [nTPM]":"186.6","Single Cell Type RNA - Peritubular cells [nTPM]":"22.2","Single Cell Type RNA - Plasma cells [nTPM]":"43.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"45.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"91.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"84.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"53.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"24.9","Single Cell Type RNA - Spermatocytes [nTPM]":"46.4","Single Cell Type RNA - Spermatogonia [nTPM]":"24.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"35.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"38.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"28.3","Single Cell Type RNA - T-cells [nTPM]":"53.7","Single Cell Type RNA - Theca cells [nTPM]":"23.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"71.0","Single Cell Type RNA - Urothelial cells [nTPM]":"65.9"},{"Gene":"NT5E","Gene synonym":["CALJA","CD73","eN","eNT","NT5"],"Ensembl":"ENSG00000135318","Gene description":"5'-nucleotidase ecto","Uniprot":["P21589"],"Chromosome":"6","Position":"85449584-85495791","Protein class":["CD markers","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"112.6","retina":"94.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Glandular and luminal cells":"58.0","Oligodendrocyte precursor cells":"61.3","Pancreatic endocrine cells":"124.8","Rod photoreceptor cells":"81.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"33.0","naive CD8 T-cell":"30.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"41","RNA blood lineage specific nTPM":{"B-cells":"33.0","T-cells":"30.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTERT-RPE1":"807.8","LHCN-M2":"934.3","TIME":"546.2","U-87 MG":"821.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017357"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3000000","Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA017357":"AB_1846330"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.66e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.32e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.02e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Tissue RNA - adipose tissue [nTPM]":"20.7","Tissue RNA - adrenal gland [nTPM]":"6.0","Tissue RNA - amygdala [nTPM]":"9.8","Tissue RNA - appendix [nTPM]":"11.9","Tissue RNA - basal ganglia [nTPM]":"11.9","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"14.1","Tissue RNA - cerebellum [nTPM]":"11.2","Tissue RNA - cerebral cortex [nTPM]":"10.7","Tissue RNA - cervix [nTPM]":"112.6","Tissue RNA - choroid plexus [nTPM]":"14.9","Tissue RNA - colon [nTPM]":"29.4","Tissue RNA - duodenum [nTPM]":"40.1","Tissue RNA - endometrium 1 [nTPM]":"49.4","Tissue RNA - epididymis [nTPM]":"6.3","Tissue RNA - esophagus [nTPM]":"8.6","Tissue RNA - fallopian tube [nTPM]":"20.7","Tissue RNA - gallbladder [nTPM]":"17.2","Tissue RNA - heart muscle [nTPM]":"8.7","Tissue RNA - hippocampal formation [nTPM]":"8.5","Tissue RNA - hypothalamus [nTPM]":"11.3","Tissue RNA - kidney [nTPM]":"17.2","Tissue RNA - liver [nTPM]":"54.8","Tissue RNA - lung [nTPM]":"6.8","Tissue RNA - lymph node [nTPM]":"9.6","Tissue RNA - medulla oblongata [nTPM]":"11.7","Tissue RNA - midbrain [nTPM]":"14.1","Tissue RNA - ovary [nTPM]":"39.3","Tissue RNA - pancreas [nTPM]":"1.8","Tissue RNA - parathyroid gland [nTPM]":"1.8","Tissue RNA - pituitary gland [nTPM]":"11.8","Tissue RNA - placenta [nTPM]":"25.3","Tissue RNA - pons [nTPM]":"13.0","Tissue RNA - prostate [nTPM]":"13.3","Tissue RNA - rectum [nTPM]":"31.9","Tissue RNA - retina [nTPM]":"94.4","Tissue RNA - salivary gland [nTPM]":"6.6","Tissue RNA - seminal vesicle [nTPM]":"34.2","Tissue RNA - skeletal muscle [nTPM]":"2.1","Tissue RNA - skin 1 [nTPM]":"6.4","Tissue RNA - small intestine [nTPM]":"20.9","Tissue RNA - smooth muscle [nTPM]":"73.9","Tissue RNA - spinal cord [nTPM]":"14.7","Tissue RNA - spleen [nTPM]":"13.0","Tissue RNA - stomach 1 [nTPM]":"8.1","Tissue RNA - testis [nTPM]":"10.4","Tissue RNA - thalamus [nTPM]":"12.7","Tissue RNA - thymus [nTPM]":"5.2","Tissue RNA - thyroid gland [nTPM]":"23.7","Tissue RNA - tongue [nTPM]":"9.8","Tissue RNA - tonsil [nTPM]":"11.3","Tissue RNA - urinary bladder [nTPM]":"15.8","Tissue RNA - vagina [nTPM]":"28.5","Tissue RNA - white matter [nTPM]":"12.1","Cell RNA - A-431 [nTPM]":"48.9","Cell RNA - A549 [nTPM]":"26.0","Cell RNA - AF22 [nTPM]":"42.9","Cell RNA - AN3-CA [nTPM]":"0.8","Cell RNA - ASC diff [nTPM]":"95.1","Cell RNA - ASC TERT1 [nTPM]":"302.4","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"306.1","Cell RNA - BJ hTERT+ [nTPM]":"332.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"147.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"275.2","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"469.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"107.3","Cell RNA - fHDF\/TERT166 [nTPM]":"270.2","Cell RNA - GAMG [nTPM]":"379.0","Cell RNA - HaCaT [nTPM]":"24.5","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"308.0","Cell RNA - HBF TERT88 [nTPM]":"348.8","Cell RNA - HDLM-2 [nTPM]":"0.8","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"7.3","Cell RNA - Hep G2 [nTPM]":"6.0","Cell RNA - HHSteC [nTPM]":"47.5","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.7","Cell RNA - HSkMC [nTPM]":"77.4","Cell RNA - hTCEpi [nTPM]":"3.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"302.0","Cell RNA - hTERT-HME1 [nTPM]":"191.3","Cell RNA - hTERT-RPE1 [nTPM]":"807.8","Cell RNA - HUVEC TERT2 [nTPM]":"124.9","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"1.4","Cell RNA - LHCN-M2 [nTPM]":"934.3","Cell RNA - MCF7 [nTPM]":"8.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"8.2","Cell RNA - PC-3 [nTPM]":"34.6","Cell RNA - REH [nTPM]":"1.5","Cell RNA - RH-30 [nTPM]":"9.5","Cell RNA - RPMI-8226 [nTPM]":"1.3","Cell RNA - RPTEC TERT1 [nTPM]":"323.1","Cell RNA - RT4 [nTPM]":"21.8","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"5.5","Cell RNA - SiHa [nTPM]":"3.8","Cell RNA - SK-BR-3 [nTPM]":"18.8","Cell RNA - SK-MEL-30 [nTPM]":"104.9","Cell RNA - SuSa [nTPM]":"2.2","Cell RNA - T-47d [nTPM]":"0.4","Cell RNA - THP-1 [nTPM]":"8.3","Cell RNA - TIME [nTPM]":"546.2","Cell RNA - U-138 MG [nTPM]":"120.6","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"152.9","Cell RNA - U-251 MG [nTPM]":"506.8","Cell RNA - U-266\/70 [nTPM]":"22.7","Cell RNA - U-266\/84 [nTPM]":"15.3","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"821.7","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"385.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"3.7","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"6.4","Blood RNA - memory B-cell [nTPM]":"23.7","Blood RNA - memory CD4 T-cell [nTPM]":"4.2","Blood RNA - memory CD8 T-cell [nTPM]":"11.7","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"33.0","Blood RNA - naive CD4 T-cell [nTPM]":"4.1","Blood RNA - naive CD8 T-cell [nTPM]":"30.7","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"1.7","Blood RNA - total PBMC [nTPM]":"6.4","Brain RNA - amygdala [nTPM]":"9.8","Brain RNA - basal ganglia [nTPM]":"11.9","Brain RNA - cerebellum [nTPM]":"11.2","Brain RNA - cerebral cortex [nTPM]":"10.7","Brain RNA - hippocampal formation [nTPM]":"8.5","Brain RNA - hypothalamus [nTPM]":"11.3","Brain RNA - medulla oblongata [nTPM]":"11.7","Brain RNA - midbrain [nTPM]":"14.1","Brain RNA - pons [nTPM]":"13.0","Brain RNA - spinal cord [nTPM]":"14.7","Brain RNA - thalamus [nTPM]":"12.7","Brain RNA - white matter [nTPM]":"12.1","Single Cell Type RNA - Adipocytes [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.8","Single Cell Type RNA - Astrocytes [nTPM]":"36.9","Single Cell Type RNA - B-cells [nTPM]":"21.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"4.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"4.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.6","Single Cell Type RNA - dendritic cells [nTPM]":"2.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"49.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.8","Single Cell Type RNA - Endothelial cells [nTPM]":"20.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.5","Single Cell Type RNA - Fibroblasts [nTPM]":"39.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"58.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"49.6","Single Cell Type RNA - Hepatocytes [nTPM]":"33.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"27.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.5","Single Cell Type RNA - Langerhans cells [nTPM]":"8.2","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"13.1","Single Cell Type RNA - Macrophages [nTPM]":"2.1","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"0.5","Single Cell Type RNA - Muller glia cells [nTPM]":"9.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"61.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"124.8","Single Cell Type RNA - Paneth cells [nTPM]":"46.0","Single Cell Type RNA - Peritubular cells [nTPM]":"25.6","Single Cell Type RNA - Plasma cells [nTPM]":"3.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"27.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"81.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.2","Single Cell Type RNA - T-cells [nTPM]":"5.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.0","Single Cell Type RNA - Urothelial cells [nTPM]":"9.6"},{"Gene":"NTHL1","Gene synonym":["NTH1","OCTS3"],"Ensembl":"ENSG00000065057","Gene description":"Nth like DNA glycosylase 1","Uniprot":["P78549"],"Chromosome":"16","Position":"2039815-2047866","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["Glycosidase","Hydrolase","Lyase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Hepatocytes":"866.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025152"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025152":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.7","Tissue RNA - adrenal gland [nTPM]":"9.3","Tissue RNA - amygdala [nTPM]":"13.8","Tissue RNA - appendix [nTPM]":"6.2","Tissue RNA - basal ganglia [nTPM]":"14.7","Tissue RNA - bone marrow [nTPM]":"4.7","Tissue RNA - breast [nTPM]":"11.0","Tissue RNA - cerebellum [nTPM]":"14.8","Tissue RNA - cerebral cortex [nTPM]":"19.7","Tissue RNA - cervix [nTPM]":"15.5","Tissue RNA - choroid plexus [nTPM]":"11.1","Tissue RNA - colon [nTPM]":"16.8","Tissue RNA - duodenum [nTPM]":"6.6","Tissue RNA - endometrium 1 [nTPM]":"15.4","Tissue RNA - epididymis [nTPM]":"3.1","Tissue RNA - esophagus [nTPM]":"11.3","Tissue RNA - fallopian tube [nTPM]":"13.8","Tissue RNA - gallbladder [nTPM]":"6.0","Tissue RNA - heart muscle [nTPM]":"15.8","Tissue RNA - hippocampal formation [nTPM]":"13.5","Tissue RNA - hypothalamus [nTPM]":"14.2","Tissue RNA - kidney [nTPM]":"9.8","Tissue RNA - liver [nTPM]":"21.9","Tissue RNA - lung [nTPM]":"10.7","Tissue RNA - lymph node [nTPM]":"8.4","Tissue RNA - medulla oblongata [nTPM]":"15.4","Tissue RNA - midbrain [nTPM]":"13.9","Tissue RNA - ovary [nTPM]":"16.1","Tissue RNA - pancreas [nTPM]":"9.9","Tissue RNA - parathyroid gland [nTPM]":"4.8","Tissue RNA - pituitary gland [nTPM]":"11.5","Tissue RNA - placenta [nTPM]":"5.6","Tissue RNA - pons [nTPM]":"15.6","Tissue RNA - prostate [nTPM]":"11.2","Tissue RNA - rectum [nTPM]":"5.6","Tissue RNA - retina [nTPM]":"1.8","Tissue RNA - salivary gland [nTPM]":"16.0","Tissue RNA - seminal vesicle [nTPM]":"11.5","Tissue RNA - skeletal muscle [nTPM]":"9.7","Tissue RNA - skin 1 [nTPM]":"9.3","Tissue RNA - small intestine [nTPM]":"11.1","Tissue RNA - smooth muscle [nTPM]":"5.3","Tissue RNA - spinal cord [nTPM]":"13.6","Tissue RNA - spleen [nTPM]":"16.7","Tissue RNA - stomach 1 [nTPM]":"13.2","Tissue RNA - testis [nTPM]":"8.7","Tissue RNA - thalamus [nTPM]":"15.2","Tissue RNA - thymus [nTPM]":"7.6","Tissue RNA - thyroid gland [nTPM]":"9.6","Tissue RNA - tongue [nTPM]":"6.8","Tissue RNA - tonsil [nTPM]":"5.9","Tissue RNA - urinary bladder [nTPM]":"11.8","Tissue RNA - vagina [nTPM]":"12.5","Tissue RNA - white matter [nTPM]":"14.2","Cell RNA - A-431 [nTPM]":"29.8","Cell RNA - A549 [nTPM]":"74.2","Cell RNA - AF22 [nTPM]":"20.8","Cell RNA - AN3-CA [nTPM]":"32.2","Cell RNA - ASC diff [nTPM]":"8.5","Cell RNA - ASC TERT1 [nTPM]":"15.9","Cell RNA - BEWO [nTPM]":"22.8","Cell RNA - BJ [nTPM]":"12.1","Cell RNA - BJ hTERT+ [nTPM]":"13.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.6","Cell RNA - CACO-2 [nTPM]":"53.0","Cell RNA - CAPAN-2 [nTPM]":"28.8","Cell RNA - Daudi [nTPM]":"63.0","Cell RNA - EFO-21 [nTPM]":"25.2","Cell RNA - fHDF\/TERT166 [nTPM]":"10.7","Cell RNA - GAMG [nTPM]":"15.1","Cell RNA - HaCaT [nTPM]":"26.2","Cell RNA - HAP1 [nTPM]":"26.1","Cell RNA - HBEC3-KT [nTPM]":"29.0","Cell RNA - HBF TERT88 [nTPM]":"4.0","Cell RNA - HDLM-2 [nTPM]":"28.9","Cell RNA - HEK 293 [nTPM]":"63.3","Cell RNA - HEL [nTPM]":"19.5","Cell RNA - HeLa [nTPM]":"47.7","Cell RNA - Hep G2 [nTPM]":"60.9","Cell RNA - HHSteC [nTPM]":"11.5","Cell RNA - HL-60 [nTPM]":"22.4","Cell RNA - HMC-1 [nTPM]":"22.3","Cell RNA - HSkMC [nTPM]":"13.2","Cell RNA - hTCEpi [nTPM]":"14.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.3","Cell RNA - hTERT-HME1 [nTPM]":"13.2","Cell RNA - hTERT-RPE1 [nTPM]":"15.4","Cell RNA - HUVEC TERT2 [nTPM]":"33.4","Cell RNA - JURKAT [nTPM]":"37.0","Cell RNA - K-562 [nTPM]":"22.2","Cell RNA - Karpas-707 [nTPM]":"22.6","Cell RNA - LHCN-M2 [nTPM]":"9.0","Cell RNA - MCF7 [nTPM]":"34.9","Cell RNA - MOLT-4 [nTPM]":"33.9","Cell RNA - NB-4 [nTPM]":"88.3","Cell RNA - NTERA-2 [nTPM]":"46.2","Cell RNA - OE19 [nTPM]":"37.3","Cell RNA - PC-3 [nTPM]":"47.3","Cell RNA - REH [nTPM]":"80.8","Cell RNA - RH-30 [nTPM]":"22.0","Cell RNA - RPMI-8226 [nTPM]":"103.5","Cell RNA - RPTEC TERT1 [nTPM]":"17.2","Cell RNA - RT4 [nTPM]":"10.7","Cell RNA - SCLC-21H [nTPM]":"43.9","Cell RNA - SH-SY5Y [nTPM]":"43.5","Cell RNA - SiHa [nTPM]":"13.2","Cell RNA - SK-BR-3 [nTPM]":"41.0","Cell RNA - SK-MEL-30 [nTPM]":"25.4","Cell RNA - SuSa [nTPM]":"7.6","Cell RNA - T-47d [nTPM]":"29.6","Cell RNA - THP-1 [nTPM]":"23.5","Cell RNA - TIME [nTPM]":"12.9","Cell RNA - U-138 MG [nTPM]":"19.9","Cell RNA - U-2 OS [nTPM]":"21.5","Cell RNA - U-2197 [nTPM]":"17.5","Cell RNA - U-251 MG [nTPM]":"23.1","Cell RNA - U-266\/70 [nTPM]":"30.3","Cell RNA - U-266\/84 [nTPM]":"38.0","Cell RNA - U-698 [nTPM]":"26.9","Cell RNA - U-87 MG [nTPM]":"8.8","Cell RNA - U-937 [nTPM]":"31.7","Cell RNA - WM-115 [nTPM]":"24.9","Blood RNA - basophil [nTPM]":"4.2","Blood RNA - classical monocyte [nTPM]":"15.0","Blood RNA - eosinophil [nTPM]":"3.4","Blood RNA - gdT-cell [nTPM]":"14.4","Blood RNA - intermediate monocyte [nTPM]":"26.0","Blood RNA - MAIT T-cell [nTPM]":"16.2","Blood RNA - memory B-cell [nTPM]":"37.5","Blood RNA - memory CD4 T-cell [nTPM]":"17.3","Blood RNA - memory CD8 T-cell [nTPM]":"16.7","Blood RNA - myeloid DC [nTPM]":"25.7","Blood RNA - naive B-cell [nTPM]":"32.8","Blood RNA - naive CD4 T-cell [nTPM]":"12.8","Blood RNA - naive CD8 T-cell [nTPM]":"15.4","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"19.1","Blood RNA - non-classical monocyte [nTPM]":"22.5","Blood RNA - plasmacytoid DC [nTPM]":"26.3","Blood RNA - T-reg [nTPM]":"34.0","Blood RNA - total PBMC [nTPM]":"14.4","Brain RNA - amygdala [nTPM]":"13.8","Brain RNA - basal ganglia [nTPM]":"14.7","Brain RNA - cerebellum [nTPM]":"14.8","Brain RNA - cerebral cortex [nTPM]":"19.7","Brain RNA - hippocampal formation [nTPM]":"13.5","Brain RNA - hypothalamus [nTPM]":"14.2","Brain RNA - medulla oblongata [nTPM]":"15.4","Brain RNA - midbrain [nTPM]":"13.9","Brain RNA - pons [nTPM]":"15.6","Brain RNA - spinal cord [nTPM]":"13.6","Brain RNA - thalamus [nTPM]":"15.2","Brain RNA - white matter [nTPM]":"14.2","Single Cell Type RNA - Adipocytes [nTPM]":"47.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.5","Single Cell Type RNA - Astrocytes [nTPM]":"2.9","Single Cell Type RNA - B-cells [nTPM]":"12.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"8.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"44.3","Single Cell Type RNA - Club cells [nTPM]":"28.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.5","Single Cell Type RNA - dendritic cells [nTPM]":"8.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"75.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"16.3","Single Cell Type RNA - Early spermatids [nTPM]":"8.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.5","Single Cell Type RNA - Endothelial cells [nTPM]":"36.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"67.4","Single Cell Type RNA - Erythroid cells [nTPM]":"26.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.3","Single Cell Type RNA - Fibroblasts [nTPM]":"17.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"23.3","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"20.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"51.0","Single Cell Type RNA - Hepatocytes [nTPM]":"866.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.4","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"85.3","Single Cell Type RNA - Ionocytes [nTPM]":"54.9","Single Cell Type RNA - Kupffer cells [nTPM]":"25.5","Single Cell Type RNA - Langerhans cells [nTPM]":"17.6","Single Cell Type RNA - Late spermatids [nTPM]":"23.8","Single Cell Type RNA - Leydig cells [nTPM]":"33.8","Single Cell Type RNA - Macrophages [nTPM]":"9.3","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"9.7","Single Cell Type RNA - Muller glia cells [nTPM]":"10.7","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.1","Single Cell Type RNA - Paneth cells [nTPM]":"81.6","Single Cell Type RNA - Peritubular cells [nTPM]":"25.2","Single Cell Type RNA - Plasma cells [nTPM]":"16.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"28.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.6","Single Cell Type RNA - Spermatocytes [nTPM]":"5.4","Single Cell Type RNA - Spermatogonia [nTPM]":"32.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.7","Single Cell Type RNA - T-cells [nTPM]":"12.2","Single Cell Type RNA - Theca cells [nTPM]":"20.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"56.8","Single Cell Type RNA - Urothelial cells [nTPM]":"21.0"},{"Gene":"NUP107","Gene synonym":["NUP84"],"Ensembl":"ENSG00000111581","Gene description":"Nucleoporin 107","Uniprot":["P57740"],"Chromosome":"12","Position":"68686951-68745809","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"89.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031679"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Nuclear membrane","Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear membrane","Centrosome"],"Antibody RRID":{"HPA031679":"AB_2673992"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.12e-9"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.28e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Tissue RNA - adipose tissue [nTPM]":"15.4","Tissue RNA - adrenal gland [nTPM]":"11.1","Tissue RNA - amygdala [nTPM]":"5.0","Tissue RNA - appendix [nTPM]":"17.9","Tissue RNA - basal ganglia [nTPM]":"6.3","Tissue RNA - bone marrow [nTPM]":"24.0","Tissue RNA - breast [nTPM]":"17.8","Tissue RNA - cerebellum [nTPM]":"8.2","Tissue RNA - cerebral cortex [nTPM]":"6.0","Tissue RNA - cervix [nTPM]":"12.9","Tissue RNA - choroid plexus [nTPM]":"6.3","Tissue RNA - colon [nTPM]":"13.0","Tissue RNA - duodenum [nTPM]":"10.3","Tissue RNA - endometrium 1 [nTPM]":"16.7","Tissue RNA - epididymis [nTPM]":"14.3","Tissue RNA - esophagus [nTPM]":"10.7","Tissue RNA - fallopian tube [nTPM]":"13.5","Tissue RNA - gallbladder [nTPM]":"9.3","Tissue RNA - heart muscle [nTPM]":"11.4","Tissue RNA - hippocampal formation [nTPM]":"4.6","Tissue RNA - hypothalamus [nTPM]":"5.0","Tissue RNA - kidney [nTPM]":"10.6","Tissue RNA - liver [nTPM]":"11.8","Tissue RNA - lung [nTPM]":"12.8","Tissue RNA - lymph node [nTPM]":"25.8","Tissue RNA - medulla oblongata [nTPM]":"5.6","Tissue RNA - midbrain [nTPM]":"5.7","Tissue RNA - ovary [nTPM]":"16.3","Tissue RNA - pancreas [nTPM]":"9.3","Tissue RNA - parathyroid gland [nTPM]":"11.8","Tissue RNA - pituitary gland [nTPM]":"6.8","Tissue RNA - placenta [nTPM]":"13.8","Tissue RNA - pons [nTPM]":"5.5","Tissue RNA - prostate [nTPM]":"12.0","Tissue RNA - rectum [nTPM]":"16.2","Tissue RNA - retina [nTPM]":"14.7","Tissue RNA - salivary gland [nTPM]":"10.3","Tissue RNA - seminal vesicle [nTPM]":"12.2","Tissue RNA - skeletal muscle [nTPM]":"11.7","Tissue RNA - skin 1 [nTPM]":"15.8","Tissue RNA - small intestine [nTPM]":"12.9","Tissue RNA - smooth muscle [nTPM]":"14.0","Tissue RNA - spinal cord [nTPM]":"5.4","Tissue RNA - spleen [nTPM]":"15.8","Tissue RNA - stomach 1 [nTPM]":"11.0","Tissue RNA - testis [nTPM]":"20.9","Tissue RNA - thalamus [nTPM]":"5.5","Tissue RNA - thymus [nTPM]":"25.6","Tissue RNA - thyroid gland [nTPM]":"10.3","Tissue RNA - tongue [nTPM]":"12.1","Tissue RNA - tonsil [nTPM]":"25.5","Tissue RNA - urinary bladder [nTPM]":"12.4","Tissue RNA - vagina [nTPM]":"10.7","Tissue RNA - white matter [nTPM]":"7.6","Cell RNA - A-431 [nTPM]":"53.1","Cell RNA - A549 [nTPM]":"66.8","Cell RNA - AF22 [nTPM]":"77.8","Cell RNA - AN3-CA [nTPM]":"56.7","Cell RNA - ASC diff [nTPM]":"22.6","Cell RNA - ASC TERT1 [nTPM]":"28.6","Cell RNA - BEWO [nTPM]":"84.1","Cell RNA - BJ [nTPM]":"56.6","Cell RNA - BJ hTERT+ [nTPM]":"32.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"83.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"68.9","Cell RNA - CACO-2 [nTPM]":"67.6","Cell RNA - CAPAN-2 [nTPM]":"43.7","Cell RNA - Daudi [nTPM]":"96.3","Cell RNA - EFO-21 [nTPM]":"53.7","Cell RNA - fHDF\/TERT166 [nTPM]":"27.2","Cell RNA - GAMG [nTPM]":"36.9","Cell RNA - HaCaT [nTPM]":"59.4","Cell RNA - HAP1 [nTPM]":"88.4","Cell RNA - HBEC3-KT [nTPM]":"41.7","Cell RNA - HBF TERT88 [nTPM]":"109.8","Cell RNA - HDLM-2 [nTPM]":"90.8","Cell RNA - HEK 293 [nTPM]":"65.6","Cell RNA - HEL [nTPM]":"110.1","Cell RNA - HeLa [nTPM]":"46.2","Cell RNA - Hep G2 [nTPM]":"57.4","Cell RNA - HHSteC [nTPM]":"14.2","Cell RNA - HL-60 [nTPM]":"97.9","Cell RNA - HMC-1 [nTPM]":"35.6","Cell RNA - HSkMC [nTPM]":"15.2","Cell RNA - hTCEpi [nTPM]":"19.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"66.5","Cell RNA - hTERT-HME1 [nTPM]":"43.2","Cell RNA - hTERT-RPE1 [nTPM]":"29.0","Cell RNA - HUVEC TERT2 [nTPM]":"50.3","Cell RNA - JURKAT [nTPM]":"54.9","Cell RNA - K-562 [nTPM]":"133.7","Cell RNA - Karpas-707 [nTPM]":"67.3","Cell RNA - LHCN-M2 [nTPM]":"52.8","Cell RNA - MCF7 [nTPM]":"64.3","Cell RNA - MOLT-4 [nTPM]":"81.3","Cell RNA - NB-4 [nTPM]":"85.2","Cell RNA - NTERA-2 [nTPM]":"85.8","Cell RNA - OE19 [nTPM]":"20.3","Cell RNA - PC-3 [nTPM]":"64.6","Cell RNA - REH [nTPM]":"81.9","Cell RNA - RH-30 [nTPM]":"93.6","Cell RNA - RPMI-8226 [nTPM]":"57.8","Cell RNA - RPTEC TERT1 [nTPM]":"36.1","Cell RNA - RT4 [nTPM]":"55.3","Cell RNA - SCLC-21H [nTPM]":"45.7","Cell RNA - SH-SY5Y [nTPM]":"46.9","Cell RNA - SiHa [nTPM]":"62.7","Cell RNA - SK-BR-3 [nTPM]":"46.5","Cell RNA - SK-MEL-30 [nTPM]":"34.4","Cell RNA - SuSa [nTPM]":"60.4","Cell RNA - T-47d [nTPM]":"69.8","Cell RNA - THP-1 [nTPM]":"46.7","Cell RNA - TIME [nTPM]":"31.1","Cell RNA - U-138 MG [nTPM]":"45.0","Cell RNA - U-2 OS [nTPM]":"45.8","Cell RNA - U-2197 [nTPM]":"53.0","Cell RNA - U-251 MG [nTPM]":"69.9","Cell RNA - U-266\/70 [nTPM]":"29.2","Cell RNA - U-266\/84 [nTPM]":"62.2","Cell RNA - U-698 [nTPM]":"115.2","Cell RNA - U-87 MG [nTPM]":"34.7","Cell RNA - U-937 [nTPM]":"70.2","Cell RNA - WM-115 [nTPM]":"54.2","Blood RNA - basophil [nTPM]":"10.5","Blood RNA - classical monocyte [nTPM]":"9.2","Blood RNA - eosinophil [nTPM]":"14.4","Blood RNA - gdT-cell [nTPM]":"17.7","Blood RNA - intermediate monocyte [nTPM]":"12.5","Blood RNA - MAIT T-cell [nTPM]":"23.4","Blood RNA - memory B-cell [nTPM]":"18.7","Blood RNA - memory CD4 T-cell [nTPM]":"17.5","Blood RNA - memory CD8 T-cell [nTPM]":"19.3","Blood RNA - myeloid DC [nTPM]":"10.2","Blood RNA - naive B-cell [nTPM]":"18.7","Blood RNA - naive CD4 T-cell [nTPM]":"21.5","Blood RNA - naive CD8 T-cell [nTPM]":"19.5","Blood RNA - neutrophil [nTPM]":"2.4","Blood RNA - NK-cell [nTPM]":"30.5","Blood RNA - non-classical monocyte [nTPM]":"23.2","Blood RNA - plasmacytoid DC [nTPM]":"8.1","Blood RNA - T-reg [nTPM]":"20.0","Blood RNA - total PBMC [nTPM]":"11.8","Brain RNA - amygdala [nTPM]":"5.0","Brain RNA - basal ganglia [nTPM]":"6.3","Brain RNA - cerebellum [nTPM]":"8.2","Brain RNA - cerebral cortex [nTPM]":"6.0","Brain RNA - hippocampal formation [nTPM]":"4.6","Brain RNA - hypothalamus [nTPM]":"5.0","Brain RNA - medulla oblongata [nTPM]":"5.6","Brain RNA - midbrain [nTPM]":"5.7","Brain RNA - pons [nTPM]":"5.5","Brain RNA - spinal cord [nTPM]":"5.4","Brain RNA - thalamus [nTPM]":"5.5","Brain RNA - white matter [nTPM]":"7.6","Single Cell Type RNA - Adipocytes [nTPM]":"18.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.7","Single Cell Type RNA - Astrocytes [nTPM]":"13.7","Single Cell Type RNA - B-cells [nTPM]":"38.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"28.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.0","Single Cell Type RNA - Bipolar cells [nTPM]":"23.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"18.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"30.7","Single Cell Type RNA - dendritic cells [nTPM]":"30.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"22.8","Single Cell Type RNA - Early spermatids [nTPM]":"45.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.2","Single Cell Type RNA - Endothelial cells [nTPM]":"20.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.5","Single Cell Type RNA - Erythroid cells [nTPM]":"64.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"30.8","Single Cell Type RNA - Fibroblasts [nTPM]":"19.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.2","Single Cell Type RNA - granulocytes [nTPM]":"15.8","Single Cell Type RNA - Granulosa cells [nTPM]":"35.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.4","Single Cell Type RNA - Hepatocytes [nTPM]":"7.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.5","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.6","Single Cell Type RNA - Ionocytes [nTPM]":"42.7","Single Cell Type RNA - Kupffer cells [nTPM]":"13.9","Single Cell Type RNA - Langerhans cells [nTPM]":"16.2","Single Cell Type RNA - Late spermatids [nTPM]":"9.6","Single Cell Type RNA - Leydig cells [nTPM]":"38.8","Single Cell Type RNA - Macrophages [nTPM]":"18.3","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"27.0","Single Cell Type RNA - Muller glia cells [nTPM]":"16.7","Single Cell Type RNA - NK-cells [nTPM]":"36.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"34.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.1","Single Cell Type RNA - Paneth cells [nTPM]":"9.9","Single Cell Type RNA - Peritubular cells [nTPM]":"21.8","Single Cell Type RNA - Plasma cells [nTPM]":"22.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"29.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.2","Single Cell Type RNA - Spermatocytes [nTPM]":"89.4","Single Cell Type RNA - Spermatogonia [nTPM]":"51.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.1","Single Cell Type RNA - T-cells [nTPM]":"27.0","Single Cell Type RNA - Theca cells [nTPM]":"24.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.8","Single Cell Type RNA - Urothelial cells [nTPM]":"12.5"},{"Gene":"NUP133","Gene synonym":["FLJ10814"],"Ensembl":"ENSG00000069248","Gene description":"Nucleoporin 133","Uniprot":["Q8WUM0"],"Chromosome":"1","Position":"229440259-229508341","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"60.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059767"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6300","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA059767":"AB_2684123"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.75e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Tissue RNA - adipose tissue [nTPM]":"12.3","Tissue RNA - adrenal gland [nTPM]":"10.7","Tissue RNA - amygdala [nTPM]":"9.2","Tissue RNA - appendix [nTPM]":"11.2","Tissue RNA - basal ganglia [nTPM]":"10.8","Tissue RNA - bone marrow [nTPM]":"12.6","Tissue RNA - breast [nTPM]":"15.8","Tissue RNA - cerebellum [nTPM]":"13.1","Tissue RNA - cerebral cortex [nTPM]":"11.9","Tissue RNA - cervix [nTPM]":"11.7","Tissue RNA - choroid plexus [nTPM]":"7.5","Tissue RNA - colon [nTPM]":"11.2","Tissue RNA - duodenum [nTPM]":"8.6","Tissue RNA - endometrium 1 [nTPM]":"14.4","Tissue RNA - epididymis [nTPM]":"11.2","Tissue RNA - esophagus [nTPM]":"10.6","Tissue RNA - fallopian tube [nTPM]":"13.9","Tissue RNA - gallbladder [nTPM]":"8.6","Tissue RNA - heart muscle [nTPM]":"15.2","Tissue RNA - hippocampal formation [nTPM]":"9.2","Tissue RNA - hypothalamus [nTPM]":"9.2","Tissue RNA - kidney [nTPM]":"12.2","Tissue RNA - liver [nTPM]":"10.1","Tissue RNA - lung [nTPM]":"10.8","Tissue RNA - lymph node [nTPM]":"14.3","Tissue RNA - medulla oblongata [nTPM]":"9.5","Tissue RNA - midbrain [nTPM]":"9.0","Tissue RNA - ovary [nTPM]":"16.5","Tissue RNA - pancreas [nTPM]":"10.0","Tissue RNA - parathyroid gland [nTPM]":"17.9","Tissue RNA - pituitary gland [nTPM]":"9.9","Tissue RNA - placenta [nTPM]":"15.1","Tissue RNA - pons [nTPM]":"9.8","Tissue RNA - prostate [nTPM]":"11.7","Tissue RNA - rectum [nTPM]":"11.4","Tissue RNA - retina [nTPM]":"19.1","Tissue RNA - salivary gland [nTPM]":"10.0","Tissue RNA - seminal vesicle [nTPM]":"11.8","Tissue RNA - skeletal muscle [nTPM]":"17.9","Tissue RNA - skin 1 [nTPM]":"13.4","Tissue RNA - small intestine [nTPM]":"9.6","Tissue RNA - smooth muscle [nTPM]":"13.2","Tissue RNA - spinal cord [nTPM]":"10.1","Tissue RNA - spleen [nTPM]":"11.6","Tissue RNA - stomach 1 [nTPM]":"9.8","Tissue RNA - testis [nTPM]":"13.0","Tissue RNA - thalamus [nTPM]":"8.9","Tissue RNA - thymus [nTPM]":"16.8","Tissue RNA - thyroid gland [nTPM]":"13.8","Tissue RNA - tongue [nTPM]":"14.3","Tissue RNA - tonsil [nTPM]":"15.4","Tissue RNA - urinary bladder [nTPM]":"11.1","Tissue RNA - vagina [nTPM]":"10.4","Tissue RNA - white matter [nTPM]":"14.5","Cell RNA - A-431 [nTPM]":"30.6","Cell RNA - A549 [nTPM]":"24.3","Cell RNA - AF22 [nTPM]":"37.0","Cell RNA - AN3-CA [nTPM]":"19.2","Cell RNA - ASC diff [nTPM]":"26.0","Cell RNA - ASC TERT1 [nTPM]":"27.8","Cell RNA - BEWO [nTPM]":"71.9","Cell RNA - BJ [nTPM]":"24.8","Cell RNA - BJ hTERT+ [nTPM]":"25.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"36.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"32.4","Cell RNA - CACO-2 [nTPM]":"28.8","Cell RNA - CAPAN-2 [nTPM]":"29.4","Cell RNA - Daudi [nTPM]":"44.1","Cell RNA - EFO-21 [nTPM]":"20.9","Cell RNA - fHDF\/TERT166 [nTPM]":"24.8","Cell RNA - GAMG [nTPM]":"16.1","Cell RNA - HaCaT [nTPM]":"39.4","Cell RNA - HAP1 [nTPM]":"51.8","Cell RNA - HBEC3-KT [nTPM]":"26.3","Cell RNA - HBF TERT88 [nTPM]":"38.4","Cell RNA - HDLM-2 [nTPM]":"26.8","Cell RNA - HEK 293 [nTPM]":"64.2","Cell RNA - HEL [nTPM]":"26.7","Cell RNA - HeLa [nTPM]":"23.6","Cell RNA - Hep G2 [nTPM]":"21.8","Cell RNA - HHSteC [nTPM]":"20.9","Cell RNA - HL-60 [nTPM]":"54.8","Cell RNA - HMC-1 [nTPM]":"20.8","Cell RNA - HSkMC [nTPM]":"21.8","Cell RNA - hTCEpi [nTPM]":"19.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.9","Cell RNA - hTERT-HME1 [nTPM]":"30.8","Cell RNA - hTERT-RPE1 [nTPM]":"25.0","Cell RNA - HUVEC TERT2 [nTPM]":"30.5","Cell RNA - JURKAT [nTPM]":"37.1","Cell RNA - K-562 [nTPM]":"61.2","Cell RNA - Karpas-707 [nTPM]":"20.6","Cell RNA - LHCN-M2 [nTPM]":"28.6","Cell RNA - MCF7 [nTPM]":"13.7","Cell RNA - MOLT-4 [nTPM]":"40.8","Cell RNA - NB-4 [nTPM]":"23.4","Cell RNA - NTERA-2 [nTPM]":"55.6","Cell RNA - OE19 [nTPM]":"42.7","Cell RNA - PC-3 [nTPM]":"21.8","Cell RNA - REH [nTPM]":"39.1","Cell RNA - RH-30 [nTPM]":"38.5","Cell RNA - RPMI-8226 [nTPM]":"43.6","Cell RNA - RPTEC TERT1 [nTPM]":"20.3","Cell RNA - RT4 [nTPM]":"26.6","Cell RNA - SCLC-21H [nTPM]":"31.7","Cell RNA - SH-SY5Y [nTPM]":"39.3","Cell RNA - SiHa [nTPM]":"36.9","Cell RNA - SK-BR-3 [nTPM]":"22.9","Cell RNA - SK-MEL-30 [nTPM]":"27.6","Cell RNA - SuSa [nTPM]":"18.0","Cell RNA - T-47d [nTPM]":"35.7","Cell RNA - THP-1 [nTPM]":"42.8","Cell RNA - TIME [nTPM]":"26.8","Cell RNA - U-138 MG [nTPM]":"16.3","Cell RNA - U-2 OS [nTPM]":"19.9","Cell RNA - U-2197 [nTPM]":"28.5","Cell RNA - U-251 MG [nTPM]":"37.3","Cell RNA - U-266\/70 [nTPM]":"19.7","Cell RNA - U-266\/84 [nTPM]":"26.1","Cell RNA - U-698 [nTPM]":"46.8","Cell RNA - U-87 MG [nTPM]":"18.6","Cell RNA - U-937 [nTPM]":"31.2","Cell RNA - WM-115 [nTPM]":"34.6","Blood RNA - basophil [nTPM]":"5.5","Blood RNA - classical monocyte [nTPM]":"5.7","Blood RNA - eosinophil [nTPM]":"4.4","Blood RNA - gdT-cell [nTPM]":"5.6","Blood RNA - intermediate monocyte [nTPM]":"5.7","Blood RNA - MAIT T-cell [nTPM]":"7.0","Blood RNA - memory B-cell [nTPM]":"5.8","Blood RNA - memory CD4 T-cell [nTPM]":"5.9","Blood RNA - memory CD8 T-cell [nTPM]":"6.2","Blood RNA - myeloid DC [nTPM]":"7.1","Blood RNA - naive B-cell [nTPM]":"4.4","Blood RNA - naive CD4 T-cell [nTPM]":"5.9","Blood RNA - naive CD8 T-cell [nTPM]":"6.3","Blood RNA - neutrophil [nTPM]":"1.9","Blood RNA - NK-cell [nTPM]":"5.5","Blood RNA - non-classical monocyte [nTPM]":"10.2","Blood RNA - plasmacytoid DC [nTPM]":"4.0","Blood RNA - T-reg [nTPM]":"5.9","Blood RNA - total PBMC [nTPM]":"5.2","Brain RNA - amygdala [nTPM]":"9.2","Brain RNA - basal ganglia [nTPM]":"10.8","Brain RNA - cerebellum [nTPM]":"13.1","Brain RNA - cerebral cortex [nTPM]":"11.9","Brain RNA - hippocampal formation [nTPM]":"9.2","Brain RNA - hypothalamus [nTPM]":"9.2","Brain RNA - medulla oblongata [nTPM]":"9.5","Brain RNA - midbrain [nTPM]":"9.0","Brain RNA - pons [nTPM]":"9.8","Brain RNA - spinal cord [nTPM]":"10.1","Brain RNA - thalamus [nTPM]":"8.9","Brain RNA - white matter [nTPM]":"14.5","Single Cell Type RNA - Adipocytes [nTPM]":"10.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.9","Single Cell Type RNA - Astrocytes [nTPM]":"26.4","Single Cell Type RNA - B-cells [nTPM]":"19.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"16.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"21.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"10.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"21.4","Single Cell Type RNA - dendritic cells [nTPM]":"11.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.7","Single Cell Type RNA - Endothelial cells [nTPM]":"10.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.2","Single Cell Type RNA - Erythroid cells [nTPM]":"21.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"48.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.8","Single Cell Type RNA - Fibroblasts [nTPM]":"13.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.4","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"17.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"12.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.8","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"44.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.5","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"13.6","Single Cell Type RNA - Langerhans cells [nTPM]":"8.6","Single Cell Type RNA - Late spermatids [nTPM]":"3.7","Single Cell Type RNA - Leydig cells [nTPM]":"12.5","Single Cell Type RNA - Macrophages [nTPM]":"10.8","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"25.3","Single Cell Type RNA - monocytes [nTPM]":"13.4","Single Cell Type RNA - Muller glia cells [nTPM]":"12.4","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"28.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"60.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.0","Single Cell Type RNA - Paneth cells [nTPM]":"4.9","Single Cell Type RNA - Peritubular cells [nTPM]":"12.0","Single Cell Type RNA - Plasma cells [nTPM]":"19.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.7","Single Cell Type RNA - Spermatocytes [nTPM]":"12.6","Single Cell Type RNA - Spermatogonia [nTPM]":"18.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"18.3","Single Cell Type RNA - T-cells [nTPM]":"13.6","Single Cell Type RNA - Theca cells [nTPM]":"11.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.0","Single Cell Type RNA - Urothelial cells [nTPM]":"6.6"},{"Gene":"NUP155","Gene synonym":["KIAA0791","N155"],"Ensembl":"ENSG00000113569","Gene description":"Nucleoporin 155","Uniprot":["O75694"],"Chromosome":"5","Position":"37288137-37371106","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Atrial fibrillation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"testis":"70.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"64.6","Late spermatids":"104.5","Spermatocytes":"48.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037775"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nuclear membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"28000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA037775":"AB_10671885"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.35e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.3","Tissue RNA - adrenal gland [nTPM]":"3.4","Tissue RNA - amygdala [nTPM]":"1.9","Tissue RNA - appendix [nTPM]":"6.7","Tissue RNA - basal ganglia [nTPM]":"2.7","Tissue RNA - bone marrow [nTPM]":"15.2","Tissue RNA - breast [nTPM]":"7.4","Tissue RNA - cerebellum [nTPM]":"5.1","Tissue RNA - cerebral cortex [nTPM]":"2.5","Tissue RNA - cervix [nTPM]":"5.2","Tissue RNA - choroid plexus [nTPM]":"3.3","Tissue RNA - colon [nTPM]":"5.6","Tissue RNA - duodenum [nTPM]":"4.9","Tissue RNA - endometrium 1 [nTPM]":"6.0","Tissue RNA - epididymis [nTPM]":"2.7","Tissue RNA - esophagus [nTPM]":"6.5","Tissue RNA - fallopian tube [nTPM]":"5.2","Tissue RNA - gallbladder [nTPM]":"4.0","Tissue RNA - heart muscle [nTPM]":"4.0","Tissue RNA - hippocampal formation [nTPM]":"2.1","Tissue RNA - hypothalamus [nTPM]":"2.5","Tissue RNA - kidney [nTPM]":"4.6","Tissue RNA - liver [nTPM]":"5.7","Tissue RNA - lung [nTPM]":"4.2","Tissue RNA - lymph node [nTPM]":"8.3","Tissue RNA - medulla oblongata [nTPM]":"2.5","Tissue RNA - midbrain [nTPM]":"2.4","Tissue RNA - ovary [nTPM]":"6.3","Tissue RNA - pancreas [nTPM]":"4.8","Tissue RNA - parathyroid gland [nTPM]":"8.1","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"8.1","Tissue RNA - pons [nTPM]":"2.9","Tissue RNA - prostate [nTPM]":"5.2","Tissue RNA - rectum [nTPM]":"6.9","Tissue RNA - retina [nTPM]":"6.6","Tissue RNA - salivary gland [nTPM]":"4.4","Tissue RNA - seminal vesicle [nTPM]":"4.2","Tissue RNA - skeletal muscle [nTPM]":"4.3","Tissue RNA - skin 1 [nTPM]":"5.1","Tissue RNA - small intestine [nTPM]":"4.5","Tissue RNA - smooth muscle [nTPM]":"6.6","Tissue RNA - spinal cord [nTPM]":"2.5","Tissue RNA - spleen [nTPM]":"5.7","Tissue RNA - stomach 1 [nTPM]":"5.0","Tissue RNA - testis [nTPM]":"70.8","Tissue RNA - thalamus [nTPM]":"2.8","Tissue RNA - thymus [nTPM]":"12.6","Tissue RNA - thyroid gland [nTPM]":"6.1","Tissue RNA - tongue [nTPM]":"5.9","Tissue RNA - tonsil [nTPM]":"9.8","Tissue RNA - urinary bladder [nTPM]":"5.7","Tissue RNA - vagina [nTPM]":"3.5","Tissue RNA - white matter [nTPM]":"4.0","Cell RNA - A-431 [nTPM]":"40.6","Cell RNA - A549 [nTPM]":"31.7","Cell RNA - AF22 [nTPM]":"33.7","Cell RNA - AN3-CA [nTPM]":"50.0","Cell RNA - ASC diff [nTPM]":"10.3","Cell RNA - ASC TERT1 [nTPM]":"15.1","Cell RNA - BEWO [nTPM]":"120.8","Cell RNA - BJ [nTPM]":"32.2","Cell RNA - BJ hTERT+ [nTPM]":"16.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"43.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"31.4","Cell RNA - CACO-2 [nTPM]":"46.9","Cell RNA - CAPAN-2 [nTPM]":"32.5","Cell RNA - Daudi [nTPM]":"46.0","Cell RNA - EFO-21 [nTPM]":"14.4","Cell RNA - fHDF\/TERT166 [nTPM]":"20.9","Cell RNA - GAMG [nTPM]":"46.7","Cell RNA - HaCaT [nTPM]":"32.2","Cell RNA - HAP1 [nTPM]":"57.5","Cell RNA - HBEC3-KT [nTPM]":"31.7","Cell RNA - HBF TERT88 [nTPM]":"67.0","Cell RNA - HDLM-2 [nTPM]":"30.4","Cell RNA - HEK 293 [nTPM]":"32.3","Cell RNA - HEL [nTPM]":"35.8","Cell RNA - HeLa [nTPM]":"109.6","Cell RNA - Hep G2 [nTPM]":"21.9","Cell RNA - HHSteC [nTPM]":"13.0","Cell RNA - HL-60 [nTPM]":"60.0","Cell RNA - HMC-1 [nTPM]":"24.0","Cell RNA - HSkMC [nTPM]":"11.1","Cell RNA - hTCEpi [nTPM]":"13.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"66.5","Cell RNA - hTERT-HME1 [nTPM]":"33.5","Cell RNA - hTERT-RPE1 [nTPM]":"11.8","Cell RNA - HUVEC TERT2 [nTPM]":"23.2","Cell RNA - JURKAT [nTPM]":"20.4","Cell RNA - K-562 [nTPM]":"65.8","Cell RNA - Karpas-707 [nTPM]":"23.8","Cell RNA - LHCN-M2 [nTPM]":"29.0","Cell RNA - MCF7 [nTPM]":"19.9","Cell RNA - MOLT-4 [nTPM]":"32.4","Cell RNA - NB-4 [nTPM]":"16.3","Cell RNA - NTERA-2 [nTPM]":"32.0","Cell RNA - OE19 [nTPM]":"24.8","Cell RNA - PC-3 [nTPM]":"28.4","Cell RNA - REH [nTPM]":"38.3","Cell RNA - RH-30 [nTPM]":"106.1","Cell RNA - RPMI-8226 [nTPM]":"36.5","Cell RNA - RPTEC TERT1 [nTPM]":"9.7","Cell RNA - RT4 [nTPM]":"38.5","Cell RNA - SCLC-21H [nTPM]":"40.6","Cell RNA - SH-SY5Y [nTPM]":"27.8","Cell RNA - SiHa [nTPM]":"74.0","Cell RNA - SK-BR-3 [nTPM]":"31.4","Cell RNA - SK-MEL-30 [nTPM]":"18.1","Cell RNA - SuSa [nTPM]":"23.8","Cell RNA - T-47d [nTPM]":"38.8","Cell RNA - THP-1 [nTPM]":"23.5","Cell RNA - TIME [nTPM]":"20.2","Cell RNA - U-138 MG [nTPM]":"51.5","Cell RNA - U-2 OS [nTPM]":"42.9","Cell RNA - U-2197 [nTPM]":"39.3","Cell RNA - U-251 MG [nTPM]":"49.5","Cell RNA - U-266\/70 [nTPM]":"26.8","Cell RNA - U-266\/84 [nTPM]":"47.9","Cell RNA - U-698 [nTPM]":"60.0","Cell RNA - U-87 MG [nTPM]":"24.1","Cell RNA - U-937 [nTPM]":"53.0","Cell RNA - WM-115 [nTPM]":"39.9","Blood RNA - basophil [nTPM]":"4.3","Blood RNA - classical monocyte [nTPM]":"2.0","Blood RNA - eosinophil [nTPM]":"3.5","Blood RNA - gdT-cell [nTPM]":"3.3","Blood RNA - intermediate monocyte [nTPM]":"4.2","Blood RNA - MAIT T-cell [nTPM]":"5.6","Blood RNA - memory B-cell [nTPM]":"3.9","Blood RNA - memory CD4 T-cell [nTPM]":"3.1","Blood RNA - memory CD8 T-cell [nTPM]":"2.9","Blood RNA - myeloid DC [nTPM]":"2.9","Blood RNA - naive B-cell [nTPM]":"2.9","Blood RNA - naive CD4 T-cell [nTPM]":"3.0","Blood RNA - naive CD8 T-cell [nTPM]":"3.5","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"4.5","Blood RNA - non-classical monocyte [nTPM]":"3.1","Blood RNA - plasmacytoid DC [nTPM]":"2.0","Blood RNA - T-reg [nTPM]":"2.4","Blood RNA - total PBMC [nTPM]":"2.7","Brain RNA - amygdala [nTPM]":"1.9","Brain RNA - basal ganglia [nTPM]":"2.7","Brain RNA - cerebellum [nTPM]":"5.1","Brain RNA - cerebral cortex [nTPM]":"2.5","Brain RNA - hippocampal formation [nTPM]":"2.1","Brain RNA - hypothalamus [nTPM]":"2.5","Brain RNA - medulla oblongata [nTPM]":"2.5","Brain RNA - midbrain [nTPM]":"2.4","Brain RNA - pons [nTPM]":"2.9","Brain RNA - spinal cord [nTPM]":"2.5","Brain RNA - thalamus [nTPM]":"2.8","Brain RNA - white matter [nTPM]":"4.0","Single Cell Type RNA - Adipocytes [nTPM]":"11.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.8","Single Cell Type RNA - Astrocytes [nTPM]":"11.8","Single Cell Type RNA - B-cells [nTPM]":"15.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"8.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"9.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.3","Single Cell Type RNA - dendritic cells [nTPM]":"9.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.0","Single Cell Type RNA - Early spermatids [nTPM]":"64.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.0","Single Cell Type RNA - Endothelial cells [nTPM]":"9.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"10.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.4","Single Cell Type RNA - Fibroblasts [nTPM]":"9.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.1","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"15.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.9","Single Cell Type RNA - Hepatocytes [nTPM]":"9.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.9","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.7","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"8.9","Single Cell Type RNA - Langerhans cells [nTPM]":"8.0","Single Cell Type RNA - Late spermatids [nTPM]":"104.5","Single Cell Type RNA - Leydig cells [nTPM]":"11.1","Single Cell Type RNA - Macrophages [nTPM]":"7.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"5.7","Single Cell Type RNA - Muller glia cells [nTPM]":"3.9","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.2","Single Cell Type RNA - Paneth cells [nTPM]":"3.8","Single Cell Type RNA - Peritubular cells [nTPM]":"10.1","Single Cell Type RNA - Plasma cells [nTPM]":"12.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.5","Single Cell Type RNA - Spermatocytes [nTPM]":"48.2","Single Cell Type RNA - Spermatogonia [nTPM]":"21.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.5","Single Cell Type RNA - T-cells [nTPM]":"9.9","Single Cell Type RNA - Theca cells [nTPM]":"10.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.3","Single Cell Type RNA - Urothelial cells [nTPM]":"4.9"},{"Gene":"NUP160","Gene synonym":["FLJ22583","KIAA0197"],"Ensembl":"ENSG00000030066","Gene description":"Nucleoporin 160","Uniprot":["Q12769"],"Chromosome":"11","Position":"47778087-47848555","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"15000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Tissue RNA - adipose tissue [nTPM]":"13.3","Tissue RNA - adrenal gland [nTPM]":"9.5","Tissue RNA - amygdala [nTPM]":"5.1","Tissue RNA - appendix [nTPM]":"17.3","Tissue RNA - basal ganglia [nTPM]":"6.6","Tissue RNA - bone marrow [nTPM]":"20.0","Tissue RNA - breast [nTPM]":"16.5","Tissue RNA - cerebellum [nTPM]":"9.4","Tissue RNA - cerebral cortex [nTPM]":"6.5","Tissue RNA - cervix [nTPM]":"13.5","Tissue RNA - choroid plexus [nTPM]":"8.6","Tissue RNA - colon [nTPM]":"12.1","Tissue RNA - duodenum [nTPM]":"11.8","Tissue RNA - endometrium 1 [nTPM]":"17.6","Tissue RNA - epididymis [nTPM]":"11.4","Tissue RNA - esophagus [nTPM]":"11.0","Tissue RNA - fallopian tube [nTPM]":"15.5","Tissue RNA - gallbladder [nTPM]":"10.9","Tissue RNA - heart muscle [nTPM]":"8.7","Tissue RNA - hippocampal formation [nTPM]":"5.1","Tissue RNA - hypothalamus [nTPM]":"6.2","Tissue RNA - kidney [nTPM]":"14.2","Tissue RNA - liver [nTPM]":"14.5","Tissue RNA - lung [nTPM]":"14.0","Tissue RNA - lymph node [nTPM]":"20.6","Tissue RNA - medulla oblongata [nTPM]":"6.4","Tissue RNA - midbrain [nTPM]":"6.2","Tissue RNA - ovary [nTPM]":"19.6","Tissue RNA - pancreas [nTPM]":"14.7","Tissue RNA - parathyroid gland [nTPM]":"16.3","Tissue RNA - pituitary gland [nTPM]":"9.9","Tissue RNA - placenta [nTPM]":"20.7","Tissue RNA - pons [nTPM]":"6.1","Tissue RNA - prostate [nTPM]":"12.7","Tissue RNA - rectum [nTPM]":"14.9","Tissue RNA - retina [nTPM]":"15.2","Tissue RNA - salivary gland [nTPM]":"11.7","Tissue RNA - seminal vesicle [nTPM]":"11.5","Tissue RNA - skeletal muscle [nTPM]":"11.1","Tissue RNA - skin 1 [nTPM]":"12.6","Tissue RNA - small intestine [nTPM]":"11.5","Tissue RNA - smooth muscle [nTPM]":"16.5","Tissue RNA - spinal cord [nTPM]":"5.8","Tissue RNA - spleen [nTPM]":"15.1","Tissue RNA - stomach 1 [nTPM]":"10.8","Tissue RNA - testis [nTPM]":"14.5","Tissue RNA - thalamus [nTPM]":"5.9","Tissue RNA - thymus [nTPM]":"30.9","Tissue RNA - thyroid gland [nTPM]":"16.9","Tissue RNA - tongue [nTPM]":"9.3","Tissue RNA - tonsil [nTPM]":"21.6","Tissue RNA - urinary bladder [nTPM]":"14.6","Tissue RNA - vagina [nTPM]":"11.7","Tissue RNA - white matter [nTPM]":"9.2","Cell RNA - A-431 [nTPM]":"24.4","Cell RNA - A549 [nTPM]":"31.7","Cell RNA - AF22 [nTPM]":"52.2","Cell RNA - AN3-CA [nTPM]":"36.6","Cell RNA - ASC diff [nTPM]":"30.3","Cell RNA - ASC TERT1 [nTPM]":"34.8","Cell RNA - BEWO [nTPM]":"67.3","Cell RNA - BJ [nTPM]":"30.7","Cell RNA - BJ hTERT+ [nTPM]":"22.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"40.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"46.8","Cell RNA - CACO-2 [nTPM]":"40.3","Cell RNA - CAPAN-2 [nTPM]":"36.2","Cell RNA - Daudi [nTPM]":"33.2","Cell RNA - EFO-21 [nTPM]":"20.3","Cell RNA - fHDF\/TERT166 [nTPM]":"28.0","Cell RNA - GAMG [nTPM]":"41.0","Cell RNA - HaCaT [nTPM]":"52.1","Cell RNA - HAP1 [nTPM]":"96.5","Cell RNA - HBEC3-KT [nTPM]":"30.4","Cell RNA - HBF TERT88 [nTPM]":"45.3","Cell RNA - HDLM-2 [nTPM]":"29.1","Cell RNA - HEK 293 [nTPM]":"66.7","Cell RNA - HEL [nTPM]":"36.6","Cell RNA - HeLa [nTPM]":"131.3","Cell RNA - Hep G2 [nTPM]":"44.1","Cell RNA - HHSteC [nTPM]":"20.2","Cell RNA - HL-60 [nTPM]":"108.1","Cell RNA - HMC-1 [nTPM]":"24.0","Cell RNA - HSkMC [nTPM]":"27.4","Cell RNA - hTCEpi [nTPM]":"18.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"29.0","Cell RNA - hTERT-HME1 [nTPM]":"56.5","Cell RNA - hTERT-RPE1 [nTPM]":"16.6","Cell RNA - HUVEC TERT2 [nTPM]":"32.5","Cell RNA - JURKAT [nTPM]":"52.9","Cell RNA - K-562 [nTPM]":"103.7","Cell RNA - Karpas-707 [nTPM]":"45.5","Cell RNA - LHCN-M2 [nTPM]":"22.0","Cell RNA - MCF7 [nTPM]":"41.9","Cell RNA - MOLT-4 [nTPM]":"72.9","Cell RNA - NB-4 [nTPM]":"47.6","Cell RNA - NTERA-2 [nTPM]":"78.4","Cell RNA - OE19 [nTPM]":"53.7","Cell RNA - PC-3 [nTPM]":"33.1","Cell RNA - REH [nTPM]":"86.2","Cell RNA - RH-30 [nTPM]":"78.3","Cell RNA - RPMI-8226 [nTPM]":"29.8","Cell RNA - RPTEC TERT1 [nTPM]":"20.9","Cell RNA - RT4 [nTPM]":"42.2","Cell RNA - SCLC-21H [nTPM]":"43.0","Cell RNA - SH-SY5Y [nTPM]":"49.0","Cell RNA - SiHa [nTPM]":"72.8","Cell RNA - SK-BR-3 [nTPM]":"35.6","Cell RNA - SK-MEL-30 [nTPM]":"27.6","Cell RNA - SuSa [nTPM]":"45.7","Cell RNA - T-47d [nTPM]":"44.6","Cell RNA - THP-1 [nTPM]":"41.1","Cell RNA - TIME [nTPM]":"22.1","Cell RNA - U-138 MG [nTPM]":"44.6","Cell RNA - U-2 OS [nTPM]":"38.4","Cell RNA - U-2197 [nTPM]":"75.2","Cell RNA - U-251 MG [nTPM]":"41.7","Cell RNA - U-266\/70 [nTPM]":"19.7","Cell RNA - U-266\/84 [nTPM]":"19.9","Cell RNA - U-698 [nTPM]":"83.8","Cell RNA - U-87 MG [nTPM]":"22.0","Cell RNA - U-937 [nTPM]":"45.2","Cell RNA - WM-115 [nTPM]":"45.2","Blood RNA - basophil [nTPM]":"8.6","Blood RNA - classical monocyte [nTPM]":"7.5","Blood RNA - eosinophil [nTPM]":"13.3","Blood RNA - gdT-cell [nTPM]":"9.9","Blood RNA - intermediate monocyte [nTPM]":"9.5","Blood RNA - MAIT T-cell [nTPM]":"13.6","Blood RNA - memory B-cell [nTPM]":"15.3","Blood RNA - memory CD4 T-cell [nTPM]":"11.7","Blood RNA - memory CD8 T-cell [nTPM]":"10.8","Blood RNA - myeloid DC [nTPM]":"12.3","Blood RNA - naive B-cell [nTPM]":"14.8","Blood RNA - naive CD4 T-cell [nTPM]":"15.4","Blood RNA - naive CD8 T-cell [nTPM]":"11.5","Blood RNA - neutrophil [nTPM]":"4.3","Blood RNA - NK-cell [nTPM]":"9.7","Blood RNA - non-classical monocyte [nTPM]":"6.8","Blood RNA - plasmacytoid DC [nTPM]":"16.3","Blood RNA - T-reg [nTPM]":"9.8","Blood RNA - total PBMC [nTPM]":"7.1","Brain RNA - amygdala [nTPM]":"5.1","Brain RNA - basal ganglia [nTPM]":"6.6","Brain RNA - cerebellum [nTPM]":"9.4","Brain RNA - cerebral cortex [nTPM]":"6.5","Brain RNA - hippocampal formation [nTPM]":"5.1","Brain RNA - hypothalamus [nTPM]":"6.2","Brain RNA - medulla oblongata [nTPM]":"6.4","Brain RNA - midbrain [nTPM]":"6.2","Brain RNA - pons [nTPM]":"6.1","Brain RNA - spinal cord [nTPM]":"5.8","Brain RNA - thalamus [nTPM]":"5.9","Brain RNA - white matter [nTPM]":"9.2","Single Cell Type RNA - Adipocytes [nTPM]":"15.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.8","Single Cell Type RNA - Astrocytes [nTPM]":"39.5","Single Cell Type RNA - B-cells [nTPM]":"31.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"22.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"35.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"20.5","Single Cell Type RNA - Bipolar cells [nTPM]":"24.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"19.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"43.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"33.1","Single Cell Type RNA - dendritic cells [nTPM]":"31.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"17.7","Single Cell Type RNA - Early spermatids [nTPM]":"27.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.3","Single Cell Type RNA - Endothelial cells [nTPM]":"17.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.2","Single Cell Type RNA - Erythroid cells [nTPM]":"19.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"35.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"30.4","Single Cell Type RNA - Fibroblasts [nTPM]":"19.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.3","Single Cell Type RNA - granulocytes [nTPM]":"19.7","Single Cell Type RNA - Granulosa cells [nTPM]":"23.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.2","Single Cell Type RNA - Hepatocytes [nTPM]":"12.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.2","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"50.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.6","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"10.1","Single Cell Type RNA - Langerhans cells [nTPM]":"19.8","Single Cell Type RNA - Late spermatids [nTPM]":"11.5","Single Cell Type RNA - Leydig cells [nTPM]":"24.2","Single Cell Type RNA - Macrophages [nTPM]":"14.4","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"44.0","Single Cell Type RNA - monocytes [nTPM]":"15.7","Single Cell Type RNA - Muller glia cells [nTPM]":"19.7","Single Cell Type RNA - NK-cells [nTPM]":"24.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"61.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"53.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.4","Single Cell Type RNA - Paneth cells [nTPM]":"8.6","Single Cell Type RNA - Peritubular cells [nTPM]":"21.8","Single Cell Type RNA - Plasma cells [nTPM]":"21.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"32.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"48.4","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.2","Single Cell Type RNA - Spermatocytes [nTPM]":"18.2","Single Cell Type RNA - Spermatogonia [nTPM]":"22.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"30.8","Single Cell Type RNA - T-cells [nTPM]":"25.3","Single Cell Type RNA - Theca cells [nTPM]":"20.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.7","Single Cell Type RNA - Urothelial cells [nTPM]":"34.8"},{"Gene":"NUP188","Gene synonym":["KIAA0169"],"Ensembl":"ENSG00000095319","Gene description":"Nucleoporin 188","Uniprot":["Q5SRE5"],"Chromosome":"9","Position":"128947699-129007096","Protein class":["Disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Cataract","Disease variant","Microphthalmia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"45.9","Spermatocytes":"52.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA061750","HPA063942"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli","Cytosol"],"Antibody RRID":{"HPA061750":"AB_2684602","HPA063942":"AB_2685156"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.20e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-3"},"Tissue RNA - adipose tissue [nTPM]":"13.1","Tissue RNA - adrenal gland [nTPM]":"15.5","Tissue RNA - amygdala [nTPM]":"9.5","Tissue RNA - appendix [nTPM]":"16.2","Tissue RNA - basal ganglia [nTPM]":"10.9","Tissue RNA - bone marrow [nTPM]":"21.4","Tissue RNA - breast [nTPM]":"11.9","Tissue RNA - cerebellum [nTPM]":"13.1","Tissue RNA - cerebral cortex [nTPM]":"10.0","Tissue RNA - cervix [nTPM]":"15.6","Tissue RNA - choroid plexus [nTPM]":"10.0","Tissue RNA - colon [nTPM]":"14.8","Tissue RNA - duodenum [nTPM]":"7.5","Tissue RNA - endometrium 1 [nTPM]":"13.1","Tissue RNA - epididymis [nTPM]":"8.0","Tissue RNA - esophagus [nTPM]":"23.7","Tissue RNA - fallopian tube [nTPM]":"11.9","Tissue RNA - gallbladder [nTPM]":"9.4","Tissue RNA - heart muscle [nTPM]":"13.6","Tissue RNA - hippocampal formation [nTPM]":"9.0","Tissue RNA - hypothalamus [nTPM]":"9.7","Tissue RNA - kidney [nTPM]":"10.4","Tissue RNA - liver [nTPM]":"9.9","Tissue RNA - lung [nTPM]":"16.7","Tissue RNA - lymph node [nTPM]":"18.0","Tissue RNA - medulla oblongata [nTPM]":"11.4","Tissue RNA - midbrain [nTPM]":"11.1","Tissue RNA - ovary [nTPM]":"11.4","Tissue RNA - pancreas [nTPM]":"12.0","Tissue RNA - parathyroid gland [nTPM]":"13.1","Tissue RNA - pituitary gland [nTPM]":"14.9","Tissue RNA - placenta [nTPM]":"11.8","Tissue RNA - pons [nTPM]":"11.8","Tissue RNA - prostate [nTPM]":"13.5","Tissue RNA - rectum [nTPM]":"11.5","Tissue RNA - retina [nTPM]":"13.7","Tissue RNA - salivary gland [nTPM]":"13.9","Tissue RNA - seminal vesicle [nTPM]":"9.8","Tissue RNA - skeletal muscle [nTPM]":"15.7","Tissue RNA - skin 1 [nTPM]":"21.4","Tissue RNA - small intestine [nTPM]":"13.4","Tissue RNA - smooth muscle [nTPM]":"13.9","Tissue RNA - spinal cord [nTPM]":"9.3","Tissue RNA - spleen [nTPM]":"16.8","Tissue RNA - stomach 1 [nTPM]":"13.6","Tissue RNA - testis [nTPM]":"56.6","Tissue RNA - thalamus [nTPM]":"10.9","Tissue RNA - thymus [nTPM]":"27.3","Tissue RNA - thyroid gland [nTPM]":"12.6","Tissue RNA - tongue [nTPM]":"10.3","Tissue RNA - tonsil [nTPM]":"20.4","Tissue RNA - urinary bladder [nTPM]":"16.1","Tissue RNA - vagina [nTPM]":"15.6","Tissue RNA - white matter [nTPM]":"11.7","Cell RNA - A-431 [nTPM]":"33.6","Cell RNA - A549 [nTPM]":"62.6","Cell RNA - AF22 [nTPM]":"50.8","Cell RNA - AN3-CA [nTPM]":"69.7","Cell RNA - ASC diff [nTPM]":"37.7","Cell RNA - ASC TERT1 [nTPM]":"37.2","Cell RNA - BEWO [nTPM]":"45.4","Cell RNA - BJ [nTPM]":"45.9","Cell RNA - BJ hTERT+ [nTPM]":"35.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"82.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"54.4","Cell RNA - CACO-2 [nTPM]":"76.3","Cell RNA - CAPAN-2 [nTPM]":"26.2","Cell RNA - Daudi [nTPM]":"58.2","Cell RNA - EFO-21 [nTPM]":"16.7","Cell RNA - fHDF\/TERT166 [nTPM]":"50.7","Cell RNA - GAMG [nTPM]":"52.9","Cell RNA - HaCaT [nTPM]":"96.6","Cell RNA - HAP1 [nTPM]":"115.2","Cell RNA - HBEC3-KT [nTPM]":"56.8","Cell RNA - HBF TERT88 [nTPM]":"61.0","Cell RNA - HDLM-2 [nTPM]":"47.1","Cell RNA - HEK 293 [nTPM]":"55.5","Cell RNA - HEL [nTPM]":"51.9","Cell RNA - HeLa [nTPM]":"113.3","Cell RNA - Hep G2 [nTPM]":"60.8","Cell RNA - HHSteC [nTPM]":"23.9","Cell RNA - HL-60 [nTPM]":"89.6","Cell RNA - HMC-1 [nTPM]":"50.2","Cell RNA - HSkMC [nTPM]":"26.0","Cell RNA - hTCEpi [nTPM]":"26.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"86.5","Cell RNA - hTERT-HME1 [nTPM]":"43.8","Cell RNA - hTERT-RPE1 [nTPM]":"24.1","Cell RNA - HUVEC TERT2 [nTPM]":"47.8","Cell RNA - JURKAT [nTPM]":"74.1","Cell RNA - K-562 [nTPM]":"116.0","Cell RNA - Karpas-707 [nTPM]":"40.3","Cell RNA - LHCN-M2 [nTPM]":"58.8","Cell RNA - MCF7 [nTPM]":"84.6","Cell RNA - MOLT-4 [nTPM]":"77.3","Cell RNA - NB-4 [nTPM]":"36.5","Cell RNA - NTERA-2 [nTPM]":"68.2","Cell RNA - OE19 [nTPM]":"63.8","Cell RNA - PC-3 [nTPM]":"59.4","Cell RNA - REH [nTPM]":"69.9","Cell RNA - RH-30 [nTPM]":"109.8","Cell RNA - RPMI-8226 [nTPM]":"59.2","Cell RNA - RPTEC TERT1 [nTPM]":"25.5","Cell RNA - RT4 [nTPM]":"37.3","Cell RNA - SCLC-21H [nTPM]":"71.2","Cell RNA - SH-SY5Y [nTPM]":"34.3","Cell RNA - SiHa [nTPM]":"118.8","Cell RNA - SK-BR-3 [nTPM]":"44.7","Cell RNA - SK-MEL-30 [nTPM]":"17.1","Cell RNA - SuSa [nTPM]":"37.2","Cell RNA - T-47d [nTPM]":"49.3","Cell RNA - THP-1 [nTPM]":"32.7","Cell RNA - TIME [nTPM]":"39.0","Cell RNA - U-138 MG [nTPM]":"67.7","Cell RNA - U-2 OS [nTPM]":"48.2","Cell RNA - U-2197 [nTPM]":"69.2","Cell RNA - U-251 MG [nTPM]":"83.5","Cell RNA - U-266\/70 [nTPM]":"34.1","Cell RNA - U-266\/84 [nTPM]":"67.9","Cell RNA - U-698 [nTPM]":"76.9","Cell RNA - U-87 MG [nTPM]":"39.5","Cell RNA - U-937 [nTPM]":"56.3","Cell RNA - WM-115 [nTPM]":"51.2","Blood RNA - basophil [nTPM]":"8.2","Blood RNA - classical monocyte [nTPM]":"4.8","Blood RNA - eosinophil [nTPM]":"1.7","Blood RNA - gdT-cell [nTPM]":"7.5","Blood RNA - intermediate monocyte [nTPM]":"8.9","Blood RNA - MAIT T-cell [nTPM]":"9.7","Blood RNA - memory B-cell [nTPM]":"4.9","Blood RNA - memory CD4 T-cell [nTPM]":"6.4","Blood RNA - memory CD8 T-cell [nTPM]":"7.4","Blood RNA - myeloid DC [nTPM]":"6.8","Blood RNA - naive B-cell [nTPM]":"4.3","Blood RNA - naive CD4 T-cell [nTPM]":"6.4","Blood RNA - naive CD8 T-cell [nTPM]":"7.0","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"5.4","Blood RNA - non-classical monocyte [nTPM]":"5.2","Blood RNA - plasmacytoid DC [nTPM]":"2.9","Blood RNA - T-reg [nTPM]":"8.3","Blood RNA - total PBMC [nTPM]":"6.8","Brain RNA - amygdala [nTPM]":"9.5","Brain RNA - basal ganglia [nTPM]":"10.9","Brain RNA - cerebellum [nTPM]":"13.1","Brain RNA - cerebral cortex [nTPM]":"10.0","Brain RNA - hippocampal formation [nTPM]":"9.0","Brain RNA - hypothalamus [nTPM]":"9.7","Brain RNA - medulla oblongata [nTPM]":"11.4","Brain RNA - midbrain [nTPM]":"11.1","Brain RNA - pons [nTPM]":"11.8","Brain RNA - spinal cord [nTPM]":"9.3","Brain RNA - thalamus [nTPM]":"10.9","Brain RNA - white matter [nTPM]":"11.7","Single Cell Type RNA - Adipocytes [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.6","Single Cell Type RNA - Astrocytes [nTPM]":"15.7","Single Cell Type RNA - B-cells [nTPM]":"10.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"16.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"5.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.0","Single Cell Type RNA - dendritic cells [nTPM]":"8.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.1","Single Cell Type RNA - Early spermatids [nTPM]":"14.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.2","Single Cell Type RNA - Endothelial cells [nTPM]":"9.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.1","Single Cell Type RNA - Erythroid cells [nTPM]":"8.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.5","Single Cell Type RNA - Fibroblasts [nTPM]":"9.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.2","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"24.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"5.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.4","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.2","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"4.7","Single Cell Type RNA - Langerhans cells [nTPM]":"6.1","Single Cell Type RNA - Late spermatids [nTPM]":"5.7","Single Cell Type RNA - Leydig cells [nTPM]":"9.6","Single Cell Type RNA - Macrophages [nTPM]":"8.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"5.3","Single Cell Type RNA - Muller glia cells [nTPM]":"6.8","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"13.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.0","Single Cell Type RNA - Paneth cells [nTPM]":"2.3","Single Cell Type RNA - Peritubular cells [nTPM]":"11.7","Single Cell Type RNA - Plasma cells [nTPM]":"8.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.4","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.1","Single Cell Type RNA - Spermatocytes [nTPM]":"52.9","Single Cell Type RNA - Spermatogonia [nTPM]":"37.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.6","Single Cell Type RNA - T-cells [nTPM]":"9.4","Single Cell Type RNA - Theca cells [nTPM]":"12.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.4","Single Cell Type RNA - Urothelial cells [nTPM]":"8.2"},{"Gene":"NUP205","Gene synonym":["C7orf14","KIAA0225"],"Ensembl":"ENSG00000155561","Gene description":"Nucleoporin 205","Uniprot":["Q92621"],"Chromosome":"7","Position":"135557917-135648757","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"24000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.90e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.5","Tissue RNA - adrenal gland [nTPM]":"6.7","Tissue RNA - amygdala [nTPM]":"2.0","Tissue RNA - appendix [nTPM]":"13.1","Tissue RNA - basal ganglia [nTPM]":"3.3","Tissue RNA - bone marrow [nTPM]":"10.7","Tissue RNA - breast [nTPM]":"11.5","Tissue RNA - cerebellum [nTPM]":"6.7","Tissue RNA - cerebral cortex [nTPM]":"2.6","Tissue RNA - cervix [nTPM]":"8.9","Tissue RNA - choroid plexus [nTPM]":"3.8","Tissue RNA - colon [nTPM]":"10.0","Tissue RNA - duodenum [nTPM]":"8.0","Tissue RNA - endometrium 1 [nTPM]":"10.7","Tissue RNA - epididymis [nTPM]":"7.2","Tissue RNA - esophagus [nTPM]":"11.0","Tissue RNA - fallopian tube [nTPM]":"10.4","Tissue RNA - gallbladder [nTPM]":"6.4","Tissue RNA - heart muscle [nTPM]":"4.9","Tissue RNA - hippocampal formation [nTPM]":"1.7","Tissue RNA - hypothalamus [nTPM]":"3.1","Tissue RNA - kidney [nTPM]":"8.0","Tissue RNA - liver [nTPM]":"6.6","Tissue RNA - lung [nTPM]":"8.4","Tissue RNA - lymph node [nTPM]":"15.0","Tissue RNA - medulla oblongata [nTPM]":"2.7","Tissue RNA - midbrain [nTPM]":"2.7","Tissue RNA - ovary [nTPM]":"11.8","Tissue RNA - pancreas [nTPM]":"6.1","Tissue RNA - parathyroid gland [nTPM]":"15.1","Tissue RNA - pituitary gland [nTPM]":"5.2","Tissue RNA - placenta [nTPM]":"11.0","Tissue RNA - pons [nTPM]":"3.2","Tissue RNA - prostate [nTPM]":"8.7","Tissue RNA - rectum [nTPM]":"12.3","Tissue RNA - retina [nTPM]":"14.8","Tissue RNA - salivary gland [nTPM]":"11.8","Tissue RNA - seminal vesicle [nTPM]":"9.0","Tissue RNA - skeletal muscle [nTPM]":"8.0","Tissue RNA - skin 1 [nTPM]":"9.6","Tissue RNA - small intestine [nTPM]":"8.3","Tissue RNA - smooth muscle [nTPM]":"12.7","Tissue RNA - spinal cord [nTPM]":"2.6","Tissue RNA - spleen [nTPM]":"10.3","Tissue RNA - stomach 1 [nTPM]":"9.0","Tissue RNA - testis [nTPM]":"11.6","Tissue RNA - thalamus [nTPM]":"3.2","Tissue RNA - thymus [nTPM]":"21.8","Tissue RNA - thyroid gland [nTPM]":"8.4","Tissue RNA - tongue [nTPM]":"8.0","Tissue RNA - tonsil [nTPM]":"17.3","Tissue RNA - urinary bladder [nTPM]":"9.9","Tissue RNA - vagina [nTPM]":"6.9","Tissue RNA - white matter [nTPM]":"4.4","Cell RNA - A-431 [nTPM]":"66.4","Cell RNA - A549 [nTPM]":"52.8","Cell RNA - AF22 [nTPM]":"69.5","Cell RNA - AN3-CA [nTPM]":"68.2","Cell RNA - ASC diff [nTPM]":"16.2","Cell RNA - ASC TERT1 [nTPM]":"26.6","Cell RNA - BEWO [nTPM]":"45.4","Cell RNA - BJ [nTPM]":"41.0","Cell RNA - BJ hTERT+ [nTPM]":"31.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"62.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"69.1","Cell RNA - CACO-2 [nTPM]":"55.1","Cell RNA - CAPAN-2 [nTPM]":"46.8","Cell RNA - Daudi [nTPM]":"84.2","Cell RNA - EFO-21 [nTPM]":"31.7","Cell RNA - fHDF\/TERT166 [nTPM]":"24.6","Cell RNA - GAMG [nTPM]":"63.0","Cell RNA - HaCaT [nTPM]":"50.1","Cell RNA - HAP1 [nTPM]":"88.5","Cell RNA - HBEC3-KT [nTPM]":"46.0","Cell RNA - HBF TERT88 [nTPM]":"80.1","Cell RNA - HDLM-2 [nTPM]":"41.9","Cell RNA - HEK 293 [nTPM]":"63.3","Cell RNA - HEL [nTPM]":"48.9","Cell RNA - HeLa [nTPM]":"52.1","Cell RNA - Hep G2 [nTPM]":"25.1","Cell RNA - HHSteC [nTPM]":"12.2","Cell RNA - HL-60 [nTPM]":"96.5","Cell RNA - HMC-1 [nTPM]":"37.0","Cell RNA - HSkMC [nTPM]":"14.5","Cell RNA - hTCEpi [nTPM]":"20.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"61.4","Cell RNA - hTERT-HME1 [nTPM]":"40.8","Cell RNA - hTERT-RPE1 [nTPM]":"21.9","Cell RNA - HUVEC TERT2 [nTPM]":"47.3","Cell RNA - JURKAT [nTPM]":"58.9","Cell RNA - K-562 [nTPM]":"115.6","Cell RNA - Karpas-707 [nTPM]":"39.1","Cell RNA - LHCN-M2 [nTPM]":"47.6","Cell RNA - MCF7 [nTPM]":"45.0","Cell RNA - MOLT-4 [nTPM]":"105.0","Cell RNA - NB-4 [nTPM]":"29.4","Cell RNA - NTERA-2 [nTPM]":"107.0","Cell RNA - OE19 [nTPM]":"51.6","Cell RNA - PC-3 [nTPM]":"46.3","Cell RNA - REH [nTPM]":"77.6","Cell RNA - RH-30 [nTPM]":"64.6","Cell RNA - RPMI-8226 [nTPM]":"66.6","Cell RNA - RPTEC TERT1 [nTPM]":"18.8","Cell RNA - RT4 [nTPM]":"52.4","Cell RNA - SCLC-21H [nTPM]":"69.3","Cell RNA - SH-SY5Y [nTPM]":"70.4","Cell RNA - SiHa [nTPM]":"67.8","Cell RNA - SK-BR-3 [nTPM]":"54.8","Cell RNA - SK-MEL-30 [nTPM]":"31.8","Cell RNA - SuSa [nTPM]":"52.4","Cell RNA - T-47d [nTPM]":"31.6","Cell RNA - THP-1 [nTPM]":"36.5","Cell RNA - TIME [nTPM]":"38.6","Cell RNA - U-138 MG [nTPM]":"51.0","Cell RNA - U-2 OS [nTPM]":"25.3","Cell RNA - U-2197 [nTPM]":"62.7","Cell RNA - U-251 MG [nTPM]":"79.5","Cell RNA - U-266\/70 [nTPM]":"28.7","Cell RNA - U-266\/84 [nTPM]":"57.2","Cell RNA - U-698 [nTPM]":"112.3","Cell RNA - U-87 MG [nTPM]":"51.7","Cell RNA - U-937 [nTPM]":"74.3","Cell RNA - WM-115 [nTPM]":"70.1","Blood RNA - basophil [nTPM]":"1.6","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"2.4","Blood RNA - intermediate monocyte [nTPM]":"3.1","Blood RNA - MAIT T-cell [nTPM]":"2.8","Blood RNA - memory B-cell [nTPM]":"2.3","Blood RNA - memory CD4 T-cell [nTPM]":"2.9","Blood RNA - memory CD8 T-cell [nTPM]":"2.5","Blood RNA - myeloid DC [nTPM]":"3.0","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"2.3","Blood RNA - naive CD8 T-cell [nTPM]":"2.7","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"2.9","Blood RNA - non-classical monocyte [nTPM]":"1.7","Blood RNA - plasmacytoid DC [nTPM]":"1.9","Blood RNA - T-reg [nTPM]":"2.9","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"2.0","Brain RNA - basal ganglia [nTPM]":"3.3","Brain RNA - cerebellum [nTPM]":"6.7","Brain RNA - cerebral cortex [nTPM]":"2.6","Brain RNA - hippocampal formation [nTPM]":"1.7","Brain RNA - hypothalamus [nTPM]":"3.1","Brain RNA - medulla oblongata [nTPM]":"2.7","Brain RNA - midbrain [nTPM]":"2.7","Brain RNA - pons [nTPM]":"3.2","Brain RNA - spinal cord [nTPM]":"2.6","Brain RNA - thalamus [nTPM]":"3.2","Brain RNA - white matter [nTPM]":"4.4","Single Cell Type RNA - Adipocytes [nTPM]":"7.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.4","Single Cell Type RNA - Astrocytes [nTPM]":"24.8","Single Cell Type RNA - B-cells [nTPM]":"15.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"6.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"10.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.1","Single Cell Type RNA - dendritic cells [nTPM]":"7.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.1","Single Cell Type RNA - Endothelial cells [nTPM]":"9.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.1","Single Cell Type RNA - Erythroid cells [nTPM]":"21.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.3","Single Cell Type RNA - Fibroblasts [nTPM]":"9.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.4","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"18.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"10.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.3","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.4","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"14.1","Single Cell Type RNA - Langerhans cells [nTPM]":"11.7","Single Cell Type RNA - Late spermatids [nTPM]":"2.4","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"12.2","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"11.4","Single Cell Type RNA - Muller glia cells [nTPM]":"4.9","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"26.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"23.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.9","Single Cell Type RNA - Paneth cells [nTPM]":"6.4","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"17.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.2","Single Cell Type RNA - Spermatocytes [nTPM]":"14.5","Single Cell Type RNA - Spermatogonia [nTPM]":"10.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.7","Single Cell Type RNA - T-cells [nTPM]":"11.9","Single Cell Type RNA - Theca cells [nTPM]":"6.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.9","Single Cell Type RNA - Urothelial cells [nTPM]":"9.4"},{"Gene":"NUP214","Gene synonym":["CAIN","CAN","D9S46E","N214"],"Ensembl":"ENSG00000126883","Gene description":"Nucleoporin 214","Uniprot":["P35658"],"Chromosome":"9","Position":"131125586-131234663","Protein class":["Cancer-related genes","Disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Host-virus interaction","mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"124.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"281.4","Granulosa cells":"169.2","Kupffer cells":"274.8","Late spermatids":"404.3","monocytes":"224.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"425.3","neutrophil":"1259.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"1259.6","monocytes":"425.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"K-562":"260.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"46000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.51e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.39e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Tissue RNA - adipose tissue [nTPM]":"29.0","Tissue RNA - adrenal gland [nTPM]":"21.2","Tissue RNA - amygdala [nTPM]":"17.0","Tissue RNA - appendix [nTPM]":"18.5","Tissue RNA - basal ganglia [nTPM]":"20.9","Tissue RNA - bone marrow [nTPM]":"42.0","Tissue RNA - breast [nTPM]":"26.0","Tissue RNA - cerebellum [nTPM]":"19.1","Tissue RNA - cerebral cortex [nTPM]":"23.2","Tissue RNA - cervix [nTPM]":"21.1","Tissue RNA - choroid plexus [nTPM]":"17.7","Tissue RNA - colon [nTPM]":"23.1","Tissue RNA - duodenum [nTPM]":"11.8","Tissue RNA - endometrium 1 [nTPM]":"21.1","Tissue RNA - epididymis [nTPM]":"17.5","Tissue RNA - esophagus [nTPM]":"33.0","Tissue RNA - fallopian tube [nTPM]":"22.6","Tissue RNA - gallbladder [nTPM]":"12.3","Tissue RNA - heart muscle [nTPM]":"26.1","Tissue RNA - hippocampal formation [nTPM]":"18.0","Tissue RNA - hypothalamus [nTPM]":"18.2","Tissue RNA - kidney [nTPM]":"43.8","Tissue RNA - liver [nTPM]":"32.0","Tissue RNA - lung [nTPM]":"22.7","Tissue RNA - lymph node [nTPM]":"15.1","Tissue RNA - medulla oblongata [nTPM]":"20.9","Tissue RNA - midbrain [nTPM]":"19.6","Tissue RNA - ovary [nTPM]":"22.1","Tissue RNA - pancreas [nTPM]":"32.8","Tissue RNA - parathyroid gland [nTPM]":"16.0","Tissue RNA - pituitary gland [nTPM]":"21.5","Tissue RNA - placenta [nTPM]":"14.4","Tissue RNA - pons [nTPM]":"20.1","Tissue RNA - prostate [nTPM]":"21.9","Tissue RNA - rectum [nTPM]":"13.4","Tissue RNA - retina [nTPM]":"15.2","Tissue RNA - salivary gland [nTPM]":"21.3","Tissue RNA - seminal vesicle [nTPM]":"12.2","Tissue RNA - skeletal muscle [nTPM]":"24.0","Tissue RNA - skin 1 [nTPM]":"28.9","Tissue RNA - small intestine [nTPM]":"23.8","Tissue RNA - smooth muscle [nTPM]":"13.0","Tissue RNA - spinal cord [nTPM]":"17.0","Tissue RNA - spleen [nTPM]":"68.8","Tissue RNA - stomach 1 [nTPM]":"25.6","Tissue RNA - testis [nTPM]":"124.2","Tissue RNA - thalamus [nTPM]":"20.4","Tissue RNA - thymus [nTPM]":"41.8","Tissue RNA - thyroid gland [nTPM]":"22.0","Tissue RNA - tongue [nTPM]":"13.1","Tissue RNA - tonsil [nTPM]":"15.4","Tissue RNA - urinary bladder [nTPM]":"21.2","Tissue RNA - vagina [nTPM]":"22.1","Tissue RNA - white matter [nTPM]":"26.3","Cell RNA - A-431 [nTPM]":"23.1","Cell RNA - A549 [nTPM]":"31.3","Cell RNA - AF22 [nTPM]":"28.1","Cell RNA - AN3-CA [nTPM]":"15.4","Cell RNA - ASC diff [nTPM]":"20.2","Cell RNA - ASC TERT1 [nTPM]":"25.1","Cell RNA - BEWO [nTPM]":"26.9","Cell RNA - BJ [nTPM]":"20.9","Cell RNA - BJ hTERT+ [nTPM]":"20.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.2","Cell RNA - CACO-2 [nTPM]":"25.2","Cell RNA - CAPAN-2 [nTPM]":"17.0","Cell RNA - Daudi [nTPM]":"36.7","Cell RNA - EFO-21 [nTPM]":"16.8","Cell RNA - fHDF\/TERT166 [nTPM]":"29.6","Cell RNA - GAMG [nTPM]":"26.5","Cell RNA - HaCaT [nTPM]":"50.1","Cell RNA - HAP1 [nTPM]":"35.2","Cell RNA - HBEC3-KT [nTPM]":"24.0","Cell RNA - HBF TERT88 [nTPM]":"32.6","Cell RNA - HDLM-2 [nTPM]":"26.4","Cell RNA - HEK 293 [nTPM]":"16.0","Cell RNA - HEL [nTPM]":"25.7","Cell RNA - HeLa [nTPM]":"45.7","Cell RNA - Hep G2 [nTPM]":"45.5","Cell RNA - HHSteC [nTPM]":"18.3","Cell RNA - HL-60 [nTPM]":"37.4","Cell RNA - HMC-1 [nTPM]":"23.3","Cell RNA - HSkMC [nTPM]":"20.7","Cell RNA - hTCEpi [nTPM]":"21.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"31.0","Cell RNA - hTERT-HME1 [nTPM]":"27.5","Cell RNA - hTERT-RPE1 [nTPM]":"16.9","Cell RNA - HUVEC TERT2 [nTPM]":"25.1","Cell RNA - JURKAT [nTPM]":"23.2","Cell RNA - K-562 [nTPM]":"260.6","Cell RNA - Karpas-707 [nTPM]":"20.5","Cell RNA - LHCN-M2 [nTPM]":"28.0","Cell RNA - MCF7 [nTPM]":"39.4","Cell RNA - MOLT-4 [nTPM]":"52.8","Cell RNA - NB-4 [nTPM]":"41.8","Cell RNA - NTERA-2 [nTPM]":"27.7","Cell RNA - OE19 [nTPM]":"30.2","Cell RNA - PC-3 [nTPM]":"27.1","Cell RNA - REH [nTPM]":"17.8","Cell RNA - RH-30 [nTPM]":"35.2","Cell RNA - RPMI-8226 [nTPM]":"36.4","Cell RNA - RPTEC TERT1 [nTPM]":"25.0","Cell RNA - RT4 [nTPM]":"24.8","Cell RNA - SCLC-21H [nTPM]":"21.4","Cell RNA - SH-SY5Y [nTPM]":"24.8","Cell RNA - SiHa [nTPM]":"35.5","Cell RNA - SK-BR-3 [nTPM]":"30.0","Cell RNA - SK-MEL-30 [nTPM]":"17.3","Cell RNA - SuSa [nTPM]":"18.4","Cell RNA - T-47d [nTPM]":"41.0","Cell RNA - THP-1 [nTPM]":"90.3","Cell RNA - TIME [nTPM]":"23.5","Cell RNA - U-138 MG [nTPM]":"44.9","Cell RNA - U-2 OS [nTPM]":"25.2","Cell RNA - U-2197 [nTPM]":"30.1","Cell RNA - U-251 MG [nTPM]":"31.6","Cell RNA - U-266\/70 [nTPM]":"18.8","Cell RNA - U-266\/84 [nTPM]":"49.7","Cell RNA - U-698 [nTPM]":"39.0","Cell RNA - U-87 MG [nTPM]":"22.3","Cell RNA - U-937 [nTPM]":"20.7","Cell RNA - WM-115 [nTPM]":"28.2","Blood RNA - basophil [nTPM]":"53.2","Blood RNA - classical monocyte [nTPM]":"425.3","Blood RNA - eosinophil [nTPM]":"174.5","Blood RNA - gdT-cell [nTPM]":"6.7","Blood RNA - intermediate monocyte [nTPM]":"181.7","Blood RNA - MAIT T-cell [nTPM]":"8.1","Blood RNA - memory B-cell [nTPM]":"13.5","Blood RNA - memory CD4 T-cell [nTPM]":"8.4","Blood RNA - memory CD8 T-cell [nTPM]":"6.4","Blood RNA - myeloid DC [nTPM]":"162.2","Blood RNA - naive B-cell [nTPM]":"11.8","Blood RNA - naive CD4 T-cell [nTPM]":"6.5","Blood RNA - naive CD8 T-cell [nTPM]":"7.5","Blood RNA - neutrophil [nTPM]":"1259.6","Blood RNA - NK-cell [nTPM]":"10.2","Blood RNA - non-classical monocyte [nTPM]":"154.8","Blood RNA - plasmacytoid DC [nTPM]":"16.9","Blood RNA - T-reg [nTPM]":"5.2","Blood RNA - total PBMC [nTPM]":"211.2","Brain RNA - amygdala [nTPM]":"17.0","Brain RNA - basal ganglia [nTPM]":"20.9","Brain RNA - cerebellum [nTPM]":"19.1","Brain RNA - cerebral cortex [nTPM]":"23.2","Brain RNA - hippocampal formation [nTPM]":"18.0","Brain RNA - hypothalamus [nTPM]":"18.2","Brain RNA - medulla oblongata [nTPM]":"20.9","Brain RNA - midbrain [nTPM]":"19.6","Brain RNA - pons [nTPM]":"20.1","Brain RNA - spinal cord [nTPM]":"17.0","Brain RNA - thalamus [nTPM]":"20.4","Brain RNA - white matter [nTPM]":"26.3","Single Cell Type RNA - Adipocytes [nTPM]":"24.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.9","Single Cell Type RNA - Astrocytes [nTPM]":"46.7","Single Cell Type RNA - B-cells [nTPM]":"27.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"20.5","Single Cell Type RNA - Bipolar cells [nTPM]":"31.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"21.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"15.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.2","Single Cell Type RNA - dendritic cells [nTPM]":"31.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"10.4","Single Cell Type RNA - Early spermatids [nTPM]":"281.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.1","Single Cell Type RNA - Endothelial cells [nTPM]":"18.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.4","Single Cell Type RNA - Erythroid cells [nTPM]":"20.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"39.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.8","Single Cell Type RNA - Fibroblasts [nTPM]":"17.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.8","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"169.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.4","Single Cell Type RNA - Hepatocytes [nTPM]":"14.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"81.2","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"41.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.6","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"274.8","Single Cell Type RNA - Langerhans cells [nTPM]":"35.3","Single Cell Type RNA - Late spermatids [nTPM]":"404.3","Single Cell Type RNA - Leydig cells [nTPM]":"23.3","Single Cell Type RNA - Macrophages [nTPM]":"120.6","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"50.6","Single Cell Type RNA - monocytes [nTPM]":"224.1","Single Cell Type RNA - Muller glia cells [nTPM]":"14.9","Single Cell Type RNA - NK-cells [nTPM]":"33.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"41.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"75.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.8","Single Cell Type RNA - Paneth cells [nTPM]":"7.7","Single Cell Type RNA - Peritubular cells [nTPM]":"20.3","Single Cell Type RNA - Plasma cells [nTPM]":"23.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"32.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"24.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"36.3","Single Cell Type RNA - Spermatocytes [nTPM]":"90.8","Single Cell Type RNA - Spermatogonia [nTPM]":"49.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.9","Single Cell Type RNA - T-cells [nTPM]":"22.4","Single Cell Type RNA - Theca cells [nTPM]":"23.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.6","Single Cell Type RNA - Urothelial cells [nTPM]":"11.3"},{"Gene":"NUP37","Gene synonym":["FLJ22618","MGC5585"],"Ensembl":"ENSG00000075188","Gene description":"Nucleoporin 37","Uniprot":["Q8NFH4"],"Chromosome":"12","Position":"102073103-102120120","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Cell cycle","Cell division","Chromosome partition","Mitosis","mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Primary microcephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"92.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056300","HPA073708"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA056300":"AB_2683092","HPA073708":"AB_2686629"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.72e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.70e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-1"},"Tissue RNA - adipose tissue [nTPM]":"11.3","Tissue RNA - adrenal gland [nTPM]":"14.2","Tissue RNA - amygdala [nTPM]":"4.1","Tissue RNA - appendix [nTPM]":"17.1","Tissue RNA - basal ganglia [nTPM]":"4.4","Tissue RNA - bone marrow [nTPM]":"22.7","Tissue RNA - breast [nTPM]":"19.5","Tissue RNA - cerebellum [nTPM]":"5.1","Tissue RNA - cerebral cortex [nTPM]":"7.8","Tissue RNA - cervix [nTPM]":"12.8","Tissue RNA - choroid plexus [nTPM]":"2.4","Tissue RNA - colon [nTPM]":"20.1","Tissue RNA - duodenum [nTPM]":"13.0","Tissue RNA - endometrium 1 [nTPM]":"11.9","Tissue RNA - epididymis [nTPM]":"21.5","Tissue RNA - esophagus [nTPM]":"18.9","Tissue RNA - fallopian tube [nTPM]":"19.0","Tissue RNA - gallbladder [nTPM]":"10.9","Tissue RNA - heart muscle [nTPM]":"17.6","Tissue RNA - hippocampal formation [nTPM]":"4.8","Tissue RNA - hypothalamus [nTPM]":"4.5","Tissue RNA - kidney [nTPM]":"15.2","Tissue RNA - liver [nTPM]":"13.0","Tissue RNA - lung [nTPM]":"11.6","Tissue RNA - lymph node [nTPM]":"28.1","Tissue RNA - medulla oblongata [nTPM]":"3.5","Tissue RNA - midbrain [nTPM]":"2.8","Tissue RNA - ovary [nTPM]":"12.1","Tissue RNA - pancreas [nTPM]":"8.7","Tissue RNA - parathyroid gland [nTPM]":"17.4","Tissue RNA - pituitary gland [nTPM]":"5.9","Tissue RNA - placenta [nTPM]":"16.9","Tissue RNA - pons [nTPM]":"3.4","Tissue RNA - prostate [nTPM]":"13.7","Tissue RNA - rectum [nTPM]":"23.8","Tissue RNA - retina [nTPM]":"10.9","Tissue RNA - salivary gland [nTPM]":"11.7","Tissue RNA - seminal vesicle [nTPM]":"13.8","Tissue RNA - skeletal muscle [nTPM]":"17.5","Tissue RNA - skin 1 [nTPM]":"13.4","Tissue RNA - small intestine [nTPM]":"14.9","Tissue RNA - smooth muscle [nTPM]":"17.7","Tissue RNA - spinal cord [nTPM]":"2.4","Tissue RNA - spleen [nTPM]":"12.0","Tissue RNA - stomach 1 [nTPM]":"12.9","Tissue RNA - testis [nTPM]":"15.1","Tissue RNA - thalamus [nTPM]":"4.3","Tissue RNA - thymus [nTPM]":"25.7","Tissue RNA - thyroid gland [nTPM]":"16.4","Tissue RNA - tongue [nTPM]":"15.5","Tissue RNA - tonsil [nTPM]":"33.5","Tissue RNA - urinary bladder [nTPM]":"17.7","Tissue RNA - vagina [nTPM]":"9.6","Tissue RNA - white matter [nTPM]":"6.3","Cell RNA - A-431 [nTPM]":"105.5","Cell RNA - A549 [nTPM]":"74.5","Cell RNA - AF22 [nTPM]":"64.2","Cell RNA - AN3-CA [nTPM]":"29.6","Cell RNA - ASC diff [nTPM]":"51.7","Cell RNA - ASC TERT1 [nTPM]":"68.4","Cell RNA - BEWO [nTPM]":"144.6","Cell RNA - BJ [nTPM]":"64.8","Cell RNA - BJ hTERT+ [nTPM]":"61.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"99.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"68.0","Cell RNA - CACO-2 [nTPM]":"97.4","Cell RNA - CAPAN-2 [nTPM]":"55.5","Cell RNA - Daudi [nTPM]":"70.1","Cell RNA - EFO-21 [nTPM]":"45.4","Cell RNA - fHDF\/TERT166 [nTPM]":"50.9","Cell RNA - GAMG [nTPM]":"68.9","Cell RNA - HaCaT [nTPM]":"76.2","Cell RNA - HAP1 [nTPM]":"113.5","Cell RNA - HBEC3-KT [nTPM]":"101.2","Cell RNA - HBF TERT88 [nTPM]":"124.4","Cell RNA - HDLM-2 [nTPM]":"98.5","Cell RNA - HEK 293 [nTPM]":"65.2","Cell RNA - HEL [nTPM]":"75.6","Cell RNA - HeLa [nTPM]":"37.2","Cell RNA - Hep G2 [nTPM]":"86.4","Cell RNA - HHSteC [nTPM]":"66.0","Cell RNA - HL-60 [nTPM]":"107.5","Cell RNA - HMC-1 [nTPM]":"22.8","Cell RNA - HSkMC [nTPM]":"53.4","Cell RNA - hTCEpi [nTPM]":"43.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"78.3","Cell RNA - hTERT-HME1 [nTPM]":"57.3","Cell RNA - hTERT-RPE1 [nTPM]":"66.7","Cell RNA - HUVEC TERT2 [nTPM]":"83.3","Cell RNA - JURKAT [nTPM]":"91.2","Cell RNA - K-562 [nTPM]":"135.5","Cell RNA - Karpas-707 [nTPM]":"25.8","Cell RNA - LHCN-M2 [nTPM]":"93.9","Cell RNA - MCF7 [nTPM]":"71.6","Cell RNA - MOLT-4 [nTPM]":"79.9","Cell RNA - NB-4 [nTPM]":"87.9","Cell RNA - NTERA-2 [nTPM]":"63.4","Cell RNA - OE19 [nTPM]":"96.8","Cell RNA - PC-3 [nTPM]":"117.2","Cell RNA - REH [nTPM]":"51.9","Cell RNA - RH-30 [nTPM]":"92.0","Cell RNA - RPMI-8226 [nTPM]":"52.8","Cell RNA - RPTEC TERT1 [nTPM]":"79.0","Cell RNA - RT4 [nTPM]":"76.1","Cell RNA - SCLC-21H [nTPM]":"33.6","Cell RNA - SH-SY5Y [nTPM]":"24.0","Cell RNA - SiHa [nTPM]":"49.8","Cell RNA - SK-BR-3 [nTPM]":"52.7","Cell RNA - SK-MEL-30 [nTPM]":"50.3","Cell RNA - SuSa [nTPM]":"72.1","Cell RNA - T-47d [nTPM]":"90.7","Cell RNA - THP-1 [nTPM]":"61.7","Cell RNA - TIME [nTPM]":"27.2","Cell RNA - U-138 MG [nTPM]":"35.7","Cell RNA - U-2 OS [nTPM]":"39.4","Cell RNA - U-2197 [nTPM]":"51.0","Cell RNA - U-251 MG [nTPM]":"91.1","Cell RNA - U-266\/70 [nTPM]":"38.5","Cell RNA - U-266\/84 [nTPM]":"78.9","Cell RNA - U-698 [nTPM]":"119.4","Cell RNA - U-87 MG [nTPM]":"41.9","Cell RNA - U-937 [nTPM]":"86.1","Cell RNA - WM-115 [nTPM]":"61.8","Blood RNA - basophil [nTPM]":"67.8","Blood RNA - classical monocyte [nTPM]":"24.0","Blood RNA - eosinophil [nTPM]":"28.3","Blood RNA - gdT-cell [nTPM]":"21.4","Blood RNA - intermediate monocyte [nTPM]":"29.3","Blood RNA - MAIT T-cell [nTPM]":"23.2","Blood RNA - memory B-cell [nTPM]":"31.2","Blood RNA - memory CD4 T-cell [nTPM]":"25.7","Blood RNA - memory CD8 T-cell [nTPM]":"21.9","Blood RNA - myeloid DC [nTPM]":"30.2","Blood RNA - naive B-cell [nTPM]":"28.2","Blood RNA - naive CD4 T-cell [nTPM]":"23.0","Blood RNA - naive CD8 T-cell [nTPM]":"26.1","Blood RNA - neutrophil [nTPM]":"7.0","Blood RNA - NK-cell [nTPM]":"23.9","Blood RNA - non-classical monocyte [nTPM]":"24.9","Blood RNA - plasmacytoid DC [nTPM]":"25.3","Blood RNA - T-reg [nTPM]":"45.4","Blood RNA - total PBMC [nTPM]":"22.5","Brain RNA - amygdala [nTPM]":"4.1","Brain RNA - basal ganglia [nTPM]":"4.4","Brain RNA - cerebellum [nTPM]":"5.1","Brain RNA - cerebral cortex [nTPM]":"7.8","Brain RNA - hippocampal formation [nTPM]":"4.8","Brain RNA - hypothalamus [nTPM]":"4.5","Brain RNA - medulla oblongata [nTPM]":"3.5","Brain RNA - midbrain [nTPM]":"2.8","Brain RNA - pons [nTPM]":"3.4","Brain RNA - spinal cord [nTPM]":"2.4","Brain RNA - thalamus [nTPM]":"4.3","Brain RNA - white matter [nTPM]":"6.3","Single Cell Type RNA - Adipocytes [nTPM]":"12.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.3","Single Cell Type RNA - Astrocytes [nTPM]":"8.8","Single Cell Type RNA - B-cells [nTPM]":"22.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"63.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Bipolar cells [nTPM]":"8.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"28.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"68.1","Single Cell Type RNA - dendritic cells [nTPM]":"17.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"25.4","Single Cell Type RNA - Ductal cells [nTPM]":"24.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"21.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.6","Single Cell Type RNA - Endothelial cells [nTPM]":"17.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"38.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"20.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"92.3","Single Cell Type RNA - Fibroblasts [nTPM]":"19.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.8","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"21.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"10.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"35.6","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.0","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"15.2","Single Cell Type RNA - Langerhans cells [nTPM]":"8.4","Single Cell Type RNA - Late spermatids [nTPM]":"6.3","Single Cell Type RNA - Leydig cells [nTPM]":"19.6","Single Cell Type RNA - Macrophages [nTPM]":"13.5","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"20.5","Single Cell Type RNA - Muller glia cells [nTPM]":"18.9","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.2","Single Cell Type RNA - Paneth cells [nTPM]":"10.6","Single Cell Type RNA - Peritubular cells [nTPM]":"18.8","Single Cell Type RNA - Plasma cells [nTPM]":"34.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"24.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"39.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"20.1","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.3","Single Cell Type RNA - Spermatocytes [nTPM]":"49.0","Single Cell Type RNA - Spermatogonia [nTPM]":"42.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"40.2","Single Cell Type RNA - T-cells [nTPM]":"18.8","Single Cell Type RNA - Theca cells [nTPM]":"31.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.5","Single Cell Type RNA - Urothelial cells [nTPM]":"16.8"},{"Gene":"NUP62","Gene synonym":["DKFZp547L134","FLJ20822","FLJ43869","IBSN","MGC841","p62","SNDI"],"Ensembl":"ENSG00000213024","Gene description":"Nucleoporin 62","Uniprot":["P37198"],"Chromosome":"19","Position":"49906825-49929763","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Host-virus interaction","mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"119.2","Late spermatids":"315.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005435","CAB020724"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"31000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB020724":null,"HPA005435":"AB_1079510"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.50e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.71e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-3"},"Tissue RNA - adipose tissue [nTPM]":"19.9","Tissue RNA - adrenal gland [nTPM]":"29.4","Tissue RNA - amygdala [nTPM]":"14.2","Tissue RNA - appendix [nTPM]":"37.3","Tissue RNA - basal ganglia [nTPM]":"13.2","Tissue RNA - bone marrow [nTPM]":"27.1","Tissue RNA - breast [nTPM]":"18.9","Tissue RNA - cerebellum [nTPM]":"18.4","Tissue RNA - cerebral cortex [nTPM]":"15.9","Tissue RNA - cervix [nTPM]":"22.5","Tissue RNA - choroid plexus [nTPM]":"14.0","Tissue RNA - colon [nTPM]":"22.5","Tissue RNA - duodenum [nTPM]":"23.7","Tissue RNA - endometrium 1 [nTPM]":"27.6","Tissue RNA - epididymis [nTPM]":"11.0","Tissue RNA - esophagus [nTPM]":"25.0","Tissue RNA - fallopian tube [nTPM]":"24.8","Tissue RNA - gallbladder [nTPM]":"18.4","Tissue RNA - heart muscle [nTPM]":"20.4","Tissue RNA - hippocampal formation [nTPM]":"13.9","Tissue RNA - hypothalamus [nTPM]":"15.7","Tissue RNA - kidney [nTPM]":"18.5","Tissue RNA - liver [nTPM]":"31.7","Tissue RNA - lung [nTPM]":"19.4","Tissue RNA - lymph node [nTPM]":"38.3","Tissue RNA - medulla oblongata [nTPM]":"15.5","Tissue RNA - midbrain [nTPM]":"14.2","Tissue RNA - ovary [nTPM]":"29.8","Tissue RNA - pancreas [nTPM]":"21.0","Tissue RNA - parathyroid gland [nTPM]":"18.0","Tissue RNA - pituitary gland [nTPM]":"22.8","Tissue RNA - placenta [nTPM]":"22.4","Tissue RNA - pons [nTPM]":"15.8","Tissue RNA - prostate [nTPM]":"19.9","Tissue RNA - rectum [nTPM]":"21.1","Tissue RNA - retina [nTPM]":"11.1","Tissue RNA - salivary gland [nTPM]":"21.8","Tissue RNA - seminal vesicle [nTPM]":"17.5","Tissue RNA - skeletal muscle [nTPM]":"33.7","Tissue RNA - skin 1 [nTPM]":"23.4","Tissue RNA - small intestine [nTPM]":"24.3","Tissue RNA - smooth muscle [nTPM]":"27.7","Tissue RNA - spinal cord [nTPM]":"13.6","Tissue RNA - spleen [nTPM]":"29.8","Tissue RNA - stomach 1 [nTPM]":"19.4","Tissue RNA - testis [nTPM]":"50.4","Tissue RNA - thalamus [nTPM]":"14.7","Tissue RNA - thymus [nTPM]":"41.9","Tissue RNA - thyroid gland [nTPM]":"16.3","Tissue RNA - tongue [nTPM]":"24.5","Tissue RNA - tonsil [nTPM]":"37.7","Tissue RNA - urinary bladder [nTPM]":"24.6","Tissue RNA - vagina [nTPM]":"20.1","Tissue RNA - white matter [nTPM]":"16.9","Cell RNA - A-431 [nTPM]":"126.7","Cell RNA - A549 [nTPM]":"115.5","Cell RNA - AF22 [nTPM]":"88.8","Cell RNA - AN3-CA [nTPM]":"74.0","Cell RNA - ASC diff [nTPM]":"26.0","Cell RNA - ASC TERT1 [nTPM]":"30.0","Cell RNA - BEWO [nTPM]":"79.7","Cell RNA - BJ [nTPM]":"92.8","Cell RNA - BJ hTERT+ [nTPM]":"65.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"99.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"98.8","Cell RNA - CACO-2 [nTPM]":"79.8","Cell RNA - CAPAN-2 [nTPM]":"71.9","Cell RNA - Daudi [nTPM]":"141.2","Cell RNA - EFO-21 [nTPM]":"51.7","Cell RNA - fHDF\/TERT166 [nTPM]":"60.8","Cell RNA - GAMG [nTPM]":"65.9","Cell RNA - HaCaT [nTPM]":"73.6","Cell RNA - HAP1 [nTPM]":"108.3","Cell RNA - HBEC3-KT [nTPM]":"62.1","Cell RNA - HBF TERT88 [nTPM]":"96.1","Cell RNA - HDLM-2 [nTPM]":"211.6","Cell RNA - HEK 293 [nTPM]":"112.0","Cell RNA - HEL [nTPM]":"109.8","Cell RNA - HeLa [nTPM]":"59.4","Cell RNA - Hep G2 [nTPM]":"72.6","Cell RNA - HHSteC [nTPM]":"30.9","Cell RNA - HL-60 [nTPM]":"108.8","Cell RNA - HMC-1 [nTPM]":"106.8","Cell RNA - HSkMC [nTPM]":"28.6","Cell RNA - hTCEpi [nTPM]":"44.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"62.0","Cell RNA - hTERT-HME1 [nTPM]":"54.8","Cell RNA - hTERT-RPE1 [nTPM]":"44.1","Cell RNA - HUVEC TERT2 [nTPM]":"71.5","Cell RNA - JURKAT [nTPM]":"82.7","Cell RNA - K-562 [nTPM]":"138.6","Cell RNA - Karpas-707 [nTPM]":"135.5","Cell RNA - LHCN-M2 [nTPM]":"69.2","Cell RNA - MCF7 [nTPM]":"59.7","Cell RNA - MOLT-4 [nTPM]":"196.7","Cell RNA - NB-4 [nTPM]":"83.6","Cell RNA - NTERA-2 [nTPM]":"82.0","Cell RNA - OE19 [nTPM]":"117.4","Cell RNA - PC-3 [nTPM]":"102.8","Cell RNA - REH [nTPM]":"170.3","Cell RNA - RH-30 [nTPM]":"99.9","Cell RNA - RPMI-8226 [nTPM]":"120.3","Cell RNA - RPTEC TERT1 [nTPM]":"46.9","Cell RNA - RT4 [nTPM]":"93.7","Cell RNA - SCLC-21H [nTPM]":"96.2","Cell RNA - SH-SY5Y [nTPM]":"68.8","Cell RNA - SiHa [nTPM]":"88.2","Cell RNA - SK-BR-3 [nTPM]":"103.8","Cell RNA - SK-MEL-30 [nTPM]":"46.3","Cell RNA - SuSa [nTPM]":"63.8","Cell RNA - T-47d [nTPM]":"78.8","Cell RNA - THP-1 [nTPM]":"51.5","Cell RNA - TIME [nTPM]":"53.0","Cell RNA - U-138 MG [nTPM]":"150.2","Cell RNA - U-2 OS [nTPM]":"85.3","Cell RNA - U-2197 [nTPM]":"49.1","Cell RNA - U-251 MG [nTPM]":"155.4","Cell RNA - U-266\/70 [nTPM]":"96.3","Cell RNA - U-266\/84 [nTPM]":"295.9","Cell RNA - U-698 [nTPM]":"132.5","Cell RNA - U-87 MG [nTPM]":"62.2","Cell RNA - U-937 [nTPM]":"90.1","Cell RNA - WM-115 [nTPM]":"113.9","Blood RNA - basophil [nTPM]":"12.3","Blood RNA - classical monocyte [nTPM]":"33.4","Blood RNA - eosinophil [nTPM]":"6.7","Blood RNA - gdT-cell [nTPM]":"17.7","Blood RNA - intermediate monocyte [nTPM]":"34.7","Blood RNA - MAIT T-cell [nTPM]":"24.1","Blood RNA - memory B-cell [nTPM]":"15.1","Blood RNA - memory CD4 T-cell [nTPM]":"17.6","Blood RNA - memory CD8 T-cell [nTPM]":"19.6","Blood RNA - myeloid DC [nTPM]":"33.1","Blood RNA - naive B-cell [nTPM]":"14.9","Blood RNA - naive CD4 T-cell [nTPM]":"11.9","Blood RNA - naive CD8 T-cell [nTPM]":"15.4","Blood RNA - neutrophil [nTPM]":"5.2","Blood RNA - NK-cell [nTPM]":"22.0","Blood RNA - non-classical monocyte [nTPM]":"20.1","Blood RNA - plasmacytoid DC [nTPM]":"29.0","Blood RNA - T-reg [nTPM]":"17.2","Blood RNA - total PBMC [nTPM]":"22.1","Brain RNA - amygdala [nTPM]":"14.2","Brain RNA - basal ganglia [nTPM]":"13.2","Brain RNA - cerebellum [nTPM]":"18.4","Brain RNA - cerebral cortex [nTPM]":"15.9","Brain RNA - hippocampal formation [nTPM]":"13.9","Brain RNA - hypothalamus [nTPM]":"15.7","Brain RNA - medulla oblongata [nTPM]":"15.5","Brain RNA - midbrain [nTPM]":"14.2","Brain RNA - pons [nTPM]":"15.8","Brain RNA - spinal cord [nTPM]":"13.6","Brain RNA - thalamus [nTPM]":"14.7","Brain RNA - white matter [nTPM]":"16.9","Single Cell Type RNA - Adipocytes [nTPM]":"16.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"22.4","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"28.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"34.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.1","Single Cell Type RNA - Bipolar cells [nTPM]":"11.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"26.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"18.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"37.0","Single Cell Type RNA - dendritic cells [nTPM]":"24.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"23.7","Single Cell Type RNA - Early spermatids [nTPM]":"113.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.9","Single Cell Type RNA - Endothelial cells [nTPM]":"27.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.6","Single Cell Type RNA - Erythroid cells [nTPM]":"39.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"48.4","Single Cell Type RNA - Fibroblasts [nTPM]":"19.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.6","Single Cell Type RNA - granulocytes [nTPM]":"23.4","Single Cell Type RNA - Granulosa cells [nTPM]":"30.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"30.4","Single Cell Type RNA - Hepatocytes [nTPM]":"13.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"49.5","Single Cell Type RNA - Horizontal cells [nTPM]":"63.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"27.0","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"36.1","Single Cell Type RNA - Langerhans cells [nTPM]":"119.2","Single Cell Type RNA - Late spermatids [nTPM]":"315.1","Single Cell Type RNA - Leydig cells [nTPM]":"24.8","Single Cell Type RNA - Macrophages [nTPM]":"41.5","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"77.1","Single Cell Type RNA - Muller glia cells [nTPM]":"19.1","Single Cell Type RNA - NK-cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.9","Single Cell Type RNA - Paneth cells [nTPM]":"22.8","Single Cell Type RNA - Peritubular cells [nTPM]":"23.0","Single Cell Type RNA - Plasma cells [nTPM]":"23.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"24.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.3","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.0","Single Cell Type RNA - Spermatocytes [nTPM]":"71.0","Single Cell Type RNA - Spermatogonia [nTPM]":"39.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"32.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"21.8","Single Cell Type RNA - T-cells [nTPM]":"24.4","Single Cell Type RNA - Theca cells [nTPM]":"17.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"33.4","Single Cell Type RNA - Urothelial cells [nTPM]":"16.6"},{"Gene":"NUP85","Gene synonym":["FLJ12549","NUP75"],"Ensembl":"ENSG00000125450","Gene description":"Nucleoporin 85","Uniprot":["Q9BW27"],"Chromosome":"17","Position":"75205659-75235758","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA061910","HPA062595"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA061910":"AB_2684634","HPA062595":"AB_2684801"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.73e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.32e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.10e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Tissue RNA - adipose tissue [nTPM]":"20.9","Tissue RNA - adrenal gland [nTPM]":"12.9","Tissue RNA - amygdala [nTPM]":"15.2","Tissue RNA - appendix [nTPM]":"18.6","Tissue RNA - basal ganglia [nTPM]":"15.7","Tissue RNA - bone marrow [nTPM]":"20.8","Tissue RNA - breast [nTPM]":"20.0","Tissue RNA - cerebellum [nTPM]":"21.8","Tissue RNA - cerebral cortex [nTPM]":"17.0","Tissue RNA - cervix [nTPM]":"21.5","Tissue RNA - choroid plexus [nTPM]":"15.4","Tissue RNA - colon [nTPM]":"18.7","Tissue RNA - duodenum [nTPM]":"15.8","Tissue RNA - endometrium 1 [nTPM]":"20.8","Tissue RNA - epididymis [nTPM]":"16.1","Tissue RNA - esophagus [nTPM]":"20.5","Tissue RNA - fallopian tube [nTPM]":"20.9","Tissue RNA - gallbladder [nTPM]":"11.6","Tissue RNA - heart muscle [nTPM]":"16.4","Tissue RNA - hippocampal formation [nTPM]":"15.6","Tissue RNA - hypothalamus [nTPM]":"14.7","Tissue RNA - kidney [nTPM]":"18.9","Tissue RNA - liver [nTPM]":"22.1","Tissue RNA - lung [nTPM]":"18.7","Tissue RNA - lymph node [nTPM]":"26.5","Tissue RNA - medulla oblongata [nTPM]":"15.8","Tissue RNA - midbrain [nTPM]":"15.1","Tissue RNA - ovary [nTPM]":"20.8","Tissue RNA - pancreas [nTPM]":"18.7","Tissue RNA - parathyroid gland [nTPM]":"12.1","Tissue RNA - pituitary gland [nTPM]":"12.7","Tissue RNA - placenta [nTPM]":"19.0","Tissue RNA - pons [nTPM]":"16.0","Tissue RNA - prostate [nTPM]":"18.9","Tissue RNA - rectum [nTPM]":"21.0","Tissue RNA - retina [nTPM]":"11.2","Tissue RNA - salivary gland [nTPM]":"16.7","Tissue RNA - seminal vesicle [nTPM]":"14.3","Tissue RNA - skeletal muscle [nTPM]":"16.7","Tissue RNA - skin 1 [nTPM]":"23.9","Tissue RNA - small intestine [nTPM]":"20.5","Tissue RNA - smooth muscle [nTPM]":"19.6","Tissue RNA - spinal cord [nTPM]":"14.9","Tissue RNA - spleen [nTPM]":"25.3","Tissue RNA - stomach 1 [nTPM]":"16.9","Tissue RNA - testis [nTPM]":"22.2","Tissue RNA - thalamus [nTPM]":"15.3","Tissue RNA - thymus [nTPM]":"33.2","Tissue RNA - thyroid gland [nTPM]":"18.0","Tissue RNA - tongue [nTPM]":"14.1","Tissue RNA - tonsil [nTPM]":"27.0","Tissue RNA - urinary bladder [nTPM]":"17.9","Tissue RNA - vagina [nTPM]":"19.5","Tissue RNA - white matter [nTPM]":"17.0","Cell RNA - A-431 [nTPM]":"66.5","Cell RNA - A549 [nTPM]":"74.0","Cell RNA - AF22 [nTPM]":"53.4","Cell RNA - AN3-CA [nTPM]":"37.3","Cell RNA - ASC diff [nTPM]":"20.3","Cell RNA - ASC TERT1 [nTPM]":"31.5","Cell RNA - BEWO [nTPM]":"74.0","Cell RNA - BJ [nTPM]":"47.3","Cell RNA - BJ hTERT+ [nTPM]":"37.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"108.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"101.7","Cell RNA - CACO-2 [nTPM]":"63.2","Cell RNA - CAPAN-2 [nTPM]":"61.4","Cell RNA - Daudi [nTPM]":"61.1","Cell RNA - EFO-21 [nTPM]":"26.6","Cell RNA - fHDF\/TERT166 [nTPM]":"41.1","Cell RNA - GAMG [nTPM]":"70.5","Cell RNA - HaCaT [nTPM]":"55.9","Cell RNA - HAP1 [nTPM]":"88.8","Cell RNA - HBEC3-KT [nTPM]":"50.6","Cell RNA - HBF TERT88 [nTPM]":"96.1","Cell RNA - HDLM-2 [nTPM]":"19.3","Cell RNA - HEK 293 [nTPM]":"70.1","Cell RNA - HEL [nTPM]":"51.0","Cell RNA - HeLa [nTPM]":"83.3","Cell RNA - Hep G2 [nTPM]":"56.3","Cell RNA - HHSteC [nTPM]":"16.6","Cell RNA - HL-60 [nTPM]":"52.8","Cell RNA - HMC-1 [nTPM]":"40.7","Cell RNA - HSkMC [nTPM]":"30.3","Cell RNA - hTCEpi [nTPM]":"30.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"76.1","Cell RNA - hTERT-HME1 [nTPM]":"32.8","Cell RNA - hTERT-RPE1 [nTPM]":"24.9","Cell RNA - HUVEC TERT2 [nTPM]":"84.7","Cell RNA - JURKAT [nTPM]":"49.0","Cell RNA - K-562 [nTPM]":"63.3","Cell RNA - Karpas-707 [nTPM]":"38.1","Cell RNA - LHCN-M2 [nTPM]":"53.8","Cell RNA - MCF7 [nTPM]":"73.0","Cell RNA - MOLT-4 [nTPM]":"100.2","Cell RNA - NB-4 [nTPM]":"64.8","Cell RNA - NTERA-2 [nTPM]":"40.0","Cell RNA - OE19 [nTPM]":"82.2","Cell RNA - PC-3 [nTPM]":"67.4","Cell RNA - REH [nTPM]":"68.9","Cell RNA - RH-30 [nTPM]":"115.1","Cell RNA - RPMI-8226 [nTPM]":"55.5","Cell RNA - RPTEC TERT1 [nTPM]":"42.1","Cell RNA - RT4 [nTPM]":"47.5","Cell RNA - SCLC-21H [nTPM]":"40.6","Cell RNA - SH-SY5Y [nTPM]":"38.5","Cell RNA - SiHa [nTPM]":"58.2","Cell RNA - SK-BR-3 [nTPM]":"73.7","Cell RNA - SK-MEL-30 [nTPM]":"42.5","Cell RNA - SuSa [nTPM]":"59.4","Cell RNA - T-47d [nTPM]":"83.3","Cell RNA - THP-1 [nTPM]":"59.1","Cell RNA - TIME [nTPM]":"30.8","Cell RNA - U-138 MG [nTPM]":"80.2","Cell RNA - U-2 OS [nTPM]":"74.4","Cell RNA - U-2197 [nTPM]":"52.5","Cell RNA - U-251 MG [nTPM]":"76.3","Cell RNA - U-266\/70 [nTPM]":"23.6","Cell RNA - U-266\/84 [nTPM]":"21.0","Cell RNA - U-698 [nTPM]":"79.2","Cell RNA - U-87 MG [nTPM]":"41.4","Cell RNA - U-937 [nTPM]":"47.3","Cell RNA - WM-115 [nTPM]":"50.6","Blood RNA - basophil [nTPM]":"8.1","Blood RNA - classical monocyte [nTPM]":"24.9","Blood RNA - eosinophil [nTPM]":"21.5","Blood RNA - gdT-cell [nTPM]":"16.1","Blood RNA - intermediate monocyte [nTPM]":"22.6","Blood RNA - MAIT T-cell [nTPM]":"22.9","Blood RNA - memory B-cell [nTPM]":"16.1","Blood RNA - memory CD4 T-cell [nTPM]":"17.5","Blood RNA - memory CD8 T-cell [nTPM]":"15.9","Blood RNA - myeloid DC [nTPM]":"20.5","Blood RNA - naive B-cell [nTPM]":"21.5","Blood RNA - naive CD4 T-cell [nTPM]":"17.0","Blood RNA - naive CD8 T-cell [nTPM]":"12.8","Blood RNA - neutrophil [nTPM]":"8.2","Blood RNA - NK-cell [nTPM]":"16.7","Blood RNA - non-classical monocyte [nTPM]":"16.5","Blood RNA - plasmacytoid DC [nTPM]":"22.5","Blood RNA - T-reg [nTPM]":"16.6","Blood RNA - total PBMC [nTPM]":"17.3","Brain RNA - amygdala [nTPM]":"15.2","Brain RNA - basal ganglia [nTPM]":"15.7","Brain RNA - cerebellum [nTPM]":"21.8","Brain RNA - cerebral cortex [nTPM]":"17.0","Brain RNA - hippocampal formation [nTPM]":"15.6","Brain RNA - hypothalamus [nTPM]":"14.7","Brain RNA - medulla oblongata [nTPM]":"15.8","Brain RNA - midbrain [nTPM]":"15.1","Brain RNA - pons [nTPM]":"16.0","Brain RNA - spinal cord [nTPM]":"14.9","Brain RNA - thalamus [nTPM]":"15.3","Brain RNA - white matter [nTPM]":"17.0","Single Cell Type RNA - Adipocytes [nTPM]":"13.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.5","Single Cell Type RNA - Astrocytes [nTPM]":"7.2","Single Cell Type RNA - B-cells [nTPM]":"13.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"19.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"7.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"15.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.0","Single Cell Type RNA - dendritic cells [nTPM]":"11.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"16.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.6","Single Cell Type RNA - Endothelial cells [nTPM]":"15.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.7","Single Cell Type RNA - Erythroid cells [nTPM]":"16.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"22.1","Single Cell Type RNA - Fibroblasts [nTPM]":"13.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.3","Single Cell Type RNA - granulocytes [nTPM]":"11.4","Single Cell Type RNA - Granulosa cells [nTPM]":"13.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.0","Single Cell Type RNA - Hepatocytes [nTPM]":"23.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.0","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.0","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"13.3","Single Cell Type RNA - Langerhans cells [nTPM]":"7.2","Single Cell Type RNA - Late spermatids [nTPM]":"3.9","Single Cell Type RNA - Leydig cells [nTPM]":"14.3","Single Cell Type RNA - Macrophages [nTPM]":"13.7","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"15.8","Single Cell Type RNA - Muller glia cells [nTPM]":"4.8","Single Cell Type RNA - NK-cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.3","Single Cell Type RNA - Paneth cells [nTPM]":"7.5","Single Cell Type RNA - Peritubular cells [nTPM]":"9.8","Single Cell Type RNA - Plasma cells [nTPM]":"8.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.8","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.2","Single Cell Type RNA - Spermatocytes [nTPM]":"24.9","Single Cell Type RNA - Spermatogonia [nTPM]":"29.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.7","Single Cell Type RNA - T-cells [nTPM]":"10.9","Single Cell Type RNA - Theca cells [nTPM]":"7.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.3","Single Cell Type RNA - Urothelial cells [nTPM]":"8.0"},{"Gene":"NUP88","Gene synonym":["MGC8530"],"Ensembl":"ENSG00000108559","Gene description":"Nucleoporin 88","Uniprot":["Q99567"],"Chromosome":"17","Position":"5360963-5419676","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"146.0","Spermatocytes":"147.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002209","HPA021816"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB002209":"AB_564128","HPA021816":"AB_1854725"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.8","Tissue RNA - adrenal gland [nTPM]":"12.0","Tissue RNA - amygdala [nTPM]":"4.2","Tissue RNA - appendix [nTPM]":"16.3","Tissue RNA - basal ganglia [nTPM]":"3.8","Tissue RNA - bone marrow [nTPM]":"20.8","Tissue RNA - breast [nTPM]":"15.2","Tissue RNA - cerebellum [nTPM]":"7.5","Tissue RNA - cerebral cortex [nTPM]":"6.0","Tissue RNA - cervix [nTPM]":"10.8","Tissue RNA - choroid plexus [nTPM]":"3.3","Tissue RNA - colon [nTPM]":"13.2","Tissue RNA - duodenum [nTPM]":"9.9","Tissue RNA - endometrium 1 [nTPM]":"10.4","Tissue RNA - epididymis [nTPM]":"16.4","Tissue RNA - esophagus [nTPM]":"12.1","Tissue RNA - fallopian tube [nTPM]":"12.4","Tissue RNA - gallbladder [nTPM]":"8.0","Tissue RNA - heart muscle [nTPM]":"12.2","Tissue RNA - hippocampal formation [nTPM]":"3.9","Tissue RNA - hypothalamus [nTPM]":"3.9","Tissue RNA - kidney [nTPM]":"15.2","Tissue RNA - liver [nTPM]":"27.3","Tissue RNA - lung [nTPM]":"9.4","Tissue RNA - lymph node [nTPM]":"26.4","Tissue RNA - medulla oblongata [nTPM]":"4.1","Tissue RNA - midbrain [nTPM]":"4.0","Tissue RNA - ovary [nTPM]":"8.5","Tissue RNA - pancreas [nTPM]":"10.2","Tissue RNA - parathyroid gland [nTPM]":"15.3","Tissue RNA - pituitary gland [nTPM]":"9.0","Tissue RNA - placenta [nTPM]":"10.9","Tissue RNA - pons [nTPM]":"4.3","Tissue RNA - prostate [nTPM]":"11.5","Tissue RNA - rectum [nTPM]":"19.3","Tissue RNA - retina [nTPM]":"9.6","Tissue RNA - salivary gland [nTPM]":"13.2","Tissue RNA - seminal vesicle [nTPM]":"10.3","Tissue RNA - skeletal muscle [nTPM]":"31.2","Tissue RNA - skin 1 [nTPM]":"12.9","Tissue RNA - small intestine [nTPM]":"11.7","Tissue RNA - smooth muscle [nTPM]":"13.7","Tissue RNA - spinal cord [nTPM]":"3.6","Tissue RNA - spleen [nTPM]":"14.8","Tissue RNA - stomach 1 [nTPM]":"12.3","Tissue RNA - testis [nTPM]":"49.3","Tissue RNA - thalamus [nTPM]":"3.8","Tissue RNA - thymus [nTPM]":"24.1","Tissue RNA - thyroid gland [nTPM]":"14.6","Tissue RNA - tongue [nTPM]":"21.6","Tissue RNA - tonsil [nTPM]":"32.9","Tissue RNA - urinary bladder [nTPM]":"15.1","Tissue RNA - vagina [nTPM]":"9.0","Tissue RNA - white matter [nTPM]":"4.2","Cell RNA - A-431 [nTPM]":"46.2","Cell RNA - A549 [nTPM]":"50.0","Cell RNA - AF22 [nTPM]":"44.0","Cell RNA - AN3-CA [nTPM]":"33.3","Cell RNA - ASC diff [nTPM]":"18.3","Cell RNA - ASC TERT1 [nTPM]":"20.0","Cell RNA - BEWO [nTPM]":"40.2","Cell RNA - BJ [nTPM]":"35.8","Cell RNA - BJ hTERT+ [nTPM]":"29.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"58.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"52.0","Cell RNA - CACO-2 [nTPM]":"41.5","Cell RNA - CAPAN-2 [nTPM]":"17.8","Cell RNA - Daudi [nTPM]":"88.6","Cell RNA - EFO-21 [nTPM]":"13.3","Cell RNA - fHDF\/TERT166 [nTPM]":"33.1","Cell RNA - GAMG [nTPM]":"38.1","Cell RNA - HaCaT [nTPM]":"43.5","Cell RNA - HAP1 [nTPM]":"73.6","Cell RNA - HBEC3-KT [nTPM]":"39.6","Cell RNA - HBF TERT88 [nTPM]":"74.7","Cell RNA - HDLM-2 [nTPM]":"22.7","Cell RNA - HEK 293 [nTPM]":"48.6","Cell RNA - HEL [nTPM]":"40.0","Cell RNA - HeLa [nTPM]":"42.7","Cell RNA - Hep G2 [nTPM]":"32.5","Cell RNA - HHSteC [nTPM]":"24.8","Cell RNA - HL-60 [nTPM]":"31.8","Cell RNA - HMC-1 [nTPM]":"34.6","Cell RNA - HSkMC [nTPM]":"14.3","Cell RNA - hTCEpi [nTPM]":"28.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"43.7","Cell RNA - hTERT-HME1 [nTPM]":"71.3","Cell RNA - hTERT-RPE1 [nTPM]":"24.5","Cell RNA - HUVEC TERT2 [nTPM]":"41.0","Cell RNA - JURKAT [nTPM]":"34.3","Cell RNA - K-562 [nTPM]":"42.3","Cell RNA - Karpas-707 [nTPM]":"22.2","Cell RNA - LHCN-M2 [nTPM]":"46.5","Cell RNA - MCF7 [nTPM]":"24.3","Cell RNA - MOLT-4 [nTPM]":"46.7","Cell RNA - NB-4 [nTPM]":"23.4","Cell RNA - NTERA-2 [nTPM]":"41.2","Cell RNA - OE19 [nTPM]":"46.4","Cell RNA - PC-3 [nTPM]":"23.9","Cell RNA - REH [nTPM]":"44.1","Cell RNA - RH-30 [nTPM]":"48.5","Cell RNA - RPMI-8226 [nTPM]":"38.7","Cell RNA - RPTEC TERT1 [nTPM]":"30.7","Cell RNA - RT4 [nTPM]":"22.3","Cell RNA - SCLC-21H [nTPM]":"17.5","Cell RNA - SH-SY5Y [nTPM]":"33.9","Cell RNA - SiHa [nTPM]":"44.0","Cell RNA - SK-BR-3 [nTPM]":"20.4","Cell RNA - SK-MEL-30 [nTPM]":"28.1","Cell RNA - SuSa [nTPM]":"33.7","Cell RNA - T-47d [nTPM]":"22.9","Cell RNA - THP-1 [nTPM]":"37.3","Cell RNA - TIME [nTPM]":"26.8","Cell RNA - U-138 MG [nTPM]":"26.4","Cell RNA - U-2 OS [nTPM]":"28.3","Cell RNA - U-2197 [nTPM]":"27.1","Cell RNA - U-251 MG [nTPM]":"66.9","Cell RNA - U-266\/70 [nTPM]":"15.0","Cell RNA - U-266\/84 [nTPM]":"19.4","Cell RNA - U-698 [nTPM]":"39.5","Cell RNA - U-87 MG [nTPM]":"31.3","Cell RNA - U-937 [nTPM]":"36.3","Cell RNA - WM-115 [nTPM]":"37.4","Blood RNA - basophil [nTPM]":"5.4","Blood RNA - classical monocyte [nTPM]":"7.6","Blood RNA - eosinophil [nTPM]":"4.3","Blood RNA - gdT-cell [nTPM]":"12.4","Blood RNA - intermediate monocyte [nTPM]":"12.2","Blood RNA - MAIT T-cell [nTPM]":"12.3","Blood RNA - memory B-cell [nTPM]":"39.1","Blood RNA - memory CD4 T-cell [nTPM]":"13.3","Blood RNA - memory CD8 T-cell [nTPM]":"15.0","Blood RNA - myeloid DC [nTPM]":"10.9","Blood RNA - naive B-cell [nTPM]":"35.7","Blood RNA - naive CD4 T-cell [nTPM]":"14.3","Blood RNA - naive CD8 T-cell [nTPM]":"15.9","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"21.1","Blood RNA - non-classical monocyte [nTPM]":"14.3","Blood RNA - plasmacytoid DC [nTPM]":"12.2","Blood RNA - T-reg [nTPM]":"17.6","Blood RNA - total PBMC [nTPM]":"11.5","Brain RNA - amygdala [nTPM]":"4.2","Brain RNA - basal ganglia [nTPM]":"3.8","Brain RNA - cerebellum [nTPM]":"7.5","Brain RNA - cerebral cortex [nTPM]":"6.0","Brain RNA - hippocampal formation [nTPM]":"3.9","Brain RNA - hypothalamus [nTPM]":"3.9","Brain RNA - medulla oblongata [nTPM]":"4.1","Brain RNA - midbrain [nTPM]":"4.0","Brain RNA - pons [nTPM]":"4.3","Brain RNA - spinal cord [nTPM]":"3.6","Brain RNA - thalamus [nTPM]":"3.8","Brain RNA - white matter [nTPM]":"4.2","Single Cell Type RNA - Adipocytes [nTPM]":"6.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.8","Single Cell Type RNA - Astrocytes [nTPM]":"10.1","Single Cell Type RNA - B-cells [nTPM]":"38.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"22.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"31.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"13.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"18.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"30.1","Single Cell Type RNA - dendritic cells [nTPM]":"19.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"27.9","Single Cell Type RNA - Early spermatids [nTPM]":"146.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"26.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.0","Single Cell Type RNA - Endothelial cells [nTPM]":"11.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.8","Single Cell Type RNA - Erythroid cells [nTPM]":"28.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"24.8","Single Cell Type RNA - Fibroblasts [nTPM]":"12.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"47.2","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"14.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.3","Single Cell Type RNA - Hepatocytes [nTPM]":"16.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.4","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.1","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"7.9","Single Cell Type RNA - Langerhans cells [nTPM]":"12.3","Single Cell Type RNA - Late spermatids [nTPM]":"38.0","Single Cell Type RNA - Leydig cells [nTPM]":"15.2","Single Cell Type RNA - Macrophages [nTPM]":"10.6","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"19.4","Single Cell Type RNA - Muller glia cells [nTPM]":"7.8","Single Cell Type RNA - NK-cells [nTPM]":"26.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"23.3","Single Cell Type RNA - Paneth cells [nTPM]":"15.4","Single Cell Type RNA - Peritubular cells [nTPM]":"10.9","Single Cell Type RNA - Plasma cells [nTPM]":"9.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"21.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.5","Single Cell Type RNA - Spermatocytes [nTPM]":"147.5","Single Cell Type RNA - Spermatogonia [nTPM]":"61.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"36.0","Single Cell Type RNA - T-cells [nTPM]":"17.9","Single Cell Type RNA - Theca cells [nTPM]":"13.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.6","Single Cell Type RNA - Urothelial cells [nTPM]":"42.8"},{"Gene":"NUP93","Gene synonym":["KIAA0095"],"Ensembl":"ENSG00000102900","Gene description":"Nucleoporin 93","Uniprot":["Q8N1F7"],"Chromosome":"16","Position":"56730118-56850286","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017937"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"38000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017937":"AB_1854726"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.72e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Tissue RNA - adipose tissue [nTPM]":"17.9","Tissue RNA - adrenal gland [nTPM]":"13.9","Tissue RNA - amygdala [nTPM]":"13.2","Tissue RNA - appendix [nTPM]":"21.3","Tissue RNA - basal ganglia [nTPM]":"17.4","Tissue RNA - bone marrow [nTPM]":"52.7","Tissue RNA - breast [nTPM]":"15.5","Tissue RNA - cerebellum [nTPM]":"6.8","Tissue RNA - cerebral cortex [nTPM]":"23.9","Tissue RNA - cervix [nTPM]":"15.3","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"17.7","Tissue RNA - duodenum [nTPM]":"9.9","Tissue RNA - endometrium 1 [nTPM]":"16.9","Tissue RNA - epididymis [nTPM]":"12.4","Tissue RNA - esophagus [nTPM]":"22.3","Tissue RNA - fallopian tube [nTPM]":"15.3","Tissue RNA - gallbladder [nTPM]":"12.4","Tissue RNA - heart muscle [nTPM]":"14.2","Tissue RNA - hippocampal formation [nTPM]":"30.6","Tissue RNA - hypothalamus [nTPM]":"10.7","Tissue RNA - kidney [nTPM]":"12.8","Tissue RNA - liver [nTPM]":"9.3","Tissue RNA - lung [nTPM]":"15.3","Tissue RNA - lymph node [nTPM]":"27.7","Tissue RNA - medulla oblongata [nTPM]":"10.7","Tissue RNA - midbrain [nTPM]":"9.3","Tissue RNA - ovary [nTPM]":"14.9","Tissue RNA - pancreas [nTPM]":"14.2","Tissue RNA - parathyroid gland [nTPM]":"14.8","Tissue RNA - pituitary gland [nTPM]":"10.8","Tissue RNA - placenta [nTPM]":"19.1","Tissue RNA - pons [nTPM]":"9.9","Tissue RNA - prostate [nTPM]":"17.7","Tissue RNA - rectum [nTPM]":"18.1","Tissue RNA - retina [nTPM]":"31.7","Tissue RNA - salivary gland [nTPM]":"12.2","Tissue RNA - seminal vesicle [nTPM]":"12.7","Tissue RNA - skeletal muscle [nTPM]":"20.0","Tissue RNA - skin 1 [nTPM]":"21.6","Tissue RNA - small intestine [nTPM]":"14.5","Tissue RNA - smooth muscle [nTPM]":"19.5","Tissue RNA - spinal cord [nTPM]":"8.3","Tissue RNA - spleen [nTPM]":"24.2","Tissue RNA - stomach 1 [nTPM]":"15.2","Tissue RNA - testis [nTPM]":"39.8","Tissue RNA - thalamus [nTPM]":"11.4","Tissue RNA - thymus [nTPM]":"34.1","Tissue RNA - thyroid gland [nTPM]":"34.3","Tissue RNA - tongue [nTPM]":"14.2","Tissue RNA - tonsil [nTPM]":"30.3","Tissue RNA - urinary bladder [nTPM]":"17.1","Tissue RNA - vagina [nTPM]":"16.1","Tissue RNA - white matter [nTPM]":"11.5","Cell RNA - A-431 [nTPM]":"71.3","Cell RNA - A549 [nTPM]":"84.5","Cell RNA - AF22 [nTPM]":"71.6","Cell RNA - AN3-CA [nTPM]":"81.0","Cell RNA - ASC diff [nTPM]":"25.9","Cell RNA - ASC TERT1 [nTPM]":"34.8","Cell RNA - BEWO [nTPM]":"81.0","Cell RNA - BJ [nTPM]":"58.7","Cell RNA - BJ hTERT+ [nTPM]":"48.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"156.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"100.1","Cell RNA - CACO-2 [nTPM]":"119.4","Cell RNA - CAPAN-2 [nTPM]":"66.1","Cell RNA - Daudi [nTPM]":"107.7","Cell RNA - EFO-21 [nTPM]":"60.4","Cell RNA - fHDF\/TERT166 [nTPM]":"54.9","Cell RNA - GAMG [nTPM]":"54.2","Cell RNA - HaCaT [nTPM]":"120.6","Cell RNA - HAP1 [nTPM]":"143.3","Cell RNA - HBEC3-KT [nTPM]":"90.1","Cell RNA - HBF TERT88 [nTPM]":"149.8","Cell RNA - HDLM-2 [nTPM]":"34.0","Cell RNA - HEK 293 [nTPM]":"81.3","Cell RNA - HEL [nTPM]":"72.6","Cell RNA - HeLa [nTPM]":"64.7","Cell RNA - Hep G2 [nTPM]":"97.3","Cell RNA - HHSteC [nTPM]":"35.0","Cell RNA - HL-60 [nTPM]":"96.7","Cell RNA - HMC-1 [nTPM]":"82.8","Cell RNA - HSkMC [nTPM]":"29.3","Cell RNA - hTCEpi [nTPM]":"35.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"104.2","Cell RNA - hTERT-HME1 [nTPM]":"64.7","Cell RNA - hTERT-RPE1 [nTPM]":"31.6","Cell RNA - HUVEC TERT2 [nTPM]":"90.8","Cell RNA - JURKAT [nTPM]":"95.3","Cell RNA - K-562 [nTPM]":"87.8","Cell RNA - Karpas-707 [nTPM]":"22.3","Cell RNA - LHCN-M2 [nTPM]":"72.3","Cell RNA - MCF7 [nTPM]":"52.4","Cell RNA - MOLT-4 [nTPM]":"136.2","Cell RNA - NB-4 [nTPM]":"81.1","Cell RNA - NTERA-2 [nTPM]":"92.1","Cell RNA - OE19 [nTPM]":"44.2","Cell RNA - PC-3 [nTPM]":"95.4","Cell RNA - REH [nTPM]":"163.9","Cell RNA - RH-30 [nTPM]":"129.4","Cell RNA - RPMI-8226 [nTPM]":"108.9","Cell RNA - RPTEC TERT1 [nTPM]":"53.1","Cell RNA - RT4 [nTPM]":"47.8","Cell RNA - SCLC-21H [nTPM]":"66.6","Cell RNA - SH-SY5Y [nTPM]":"44.1","Cell RNA - SiHa [nTPM]":"159.1","Cell RNA - SK-BR-3 [nTPM]":"54.6","Cell RNA - SK-MEL-30 [nTPM]":"47.3","Cell RNA - SuSa [nTPM]":"77.4","Cell RNA - T-47d [nTPM]":"43.0","Cell RNA - THP-1 [nTPM]":"57.9","Cell RNA - TIME [nTPM]":"55.3","Cell RNA - U-138 MG [nTPM]":"68.1","Cell RNA - U-2 OS [nTPM]":"74.0","Cell RNA - U-2197 [nTPM]":"57.8","Cell RNA - U-251 MG [nTPM]":"67.5","Cell RNA - U-266\/70 [nTPM]":"35.0","Cell RNA - U-266\/84 [nTPM]":"60.7","Cell RNA - U-698 [nTPM]":"190.2","Cell RNA - U-87 MG [nTPM]":"47.4","Cell RNA - U-937 [nTPM]":"88.5","Cell RNA - WM-115 [nTPM]":"67.5","Blood RNA - basophil [nTPM]":"19.3","Blood RNA - classical monocyte [nTPM]":"49.9","Blood RNA - eosinophil [nTPM]":"195.7","Blood RNA - gdT-cell [nTPM]":"38.9","Blood RNA - intermediate monocyte [nTPM]":"77.2","Blood RNA - MAIT T-cell [nTPM]":"45.2","Blood RNA - memory B-cell [nTPM]":"45.4","Blood RNA - memory CD4 T-cell [nTPM]":"28.3","Blood RNA - memory CD8 T-cell [nTPM]":"40.9","Blood RNA - myeloid DC [nTPM]":"60.9","Blood RNA - naive B-cell [nTPM]":"45.4","Blood RNA - naive CD4 T-cell [nTPM]":"28.7","Blood RNA - naive CD8 T-cell [nTPM]":"41.0","Blood RNA - neutrophil [nTPM]":"11.8","Blood RNA - NK-cell [nTPM]":"51.8","Blood RNA - non-classical monocyte [nTPM]":"77.5","Blood RNA - plasmacytoid DC [nTPM]":"28.7","Blood RNA - T-reg [nTPM]":"39.7","Blood RNA - total PBMC [nTPM]":"47.4","Brain RNA - amygdala [nTPM]":"13.2","Brain RNA - basal ganglia [nTPM]":"17.4","Brain RNA - cerebellum [nTPM]":"6.8","Brain RNA - cerebral cortex [nTPM]":"23.9","Brain RNA - hippocampal formation [nTPM]":"30.6","Brain RNA - hypothalamus [nTPM]":"10.7","Brain RNA - medulla oblongata [nTPM]":"10.7","Brain RNA - midbrain [nTPM]":"9.3","Brain RNA - pons [nTPM]":"9.9","Brain RNA - spinal cord [nTPM]":"8.3","Brain RNA - thalamus [nTPM]":"11.4","Brain RNA - white matter [nTPM]":"11.5","Single Cell Type RNA - Adipocytes [nTPM]":"11.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.3","Single Cell Type RNA - Astrocytes [nTPM]":"17.6","Single Cell Type RNA - B-cells [nTPM]":"13.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"20.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"68.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"20.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"21.1","Single Cell Type RNA - dendritic cells [nTPM]":"9.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"24.6","Single Cell Type RNA - Early spermatids [nTPM]":"11.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.8","Single Cell Type RNA - Endothelial cells [nTPM]":"16.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.9","Single Cell Type RNA - Erythroid cells [nTPM]":"33.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"51.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"31.7","Single Cell Type RNA - Fibroblasts [nTPM]":"12.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.6","Single Cell Type RNA - granulocytes [nTPM]":"17.2","Single Cell Type RNA - Granulosa cells [nTPM]":"22.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.8","Single Cell Type RNA - Hepatocytes [nTPM]":"7.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"26.6","Single Cell Type RNA - Horizontal cells [nTPM]":"38.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"49.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.2","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"17.8","Single Cell Type RNA - Langerhans cells [nTPM]":"23.8","Single Cell Type RNA - Late spermatids [nTPM]":"7.7","Single Cell Type RNA - Leydig cells [nTPM]":"23.3","Single Cell Type RNA - Macrophages [nTPM]":"17.3","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"33.7","Single Cell Type RNA - monocytes [nTPM]":"30.3","Single Cell Type RNA - Muller glia cells [nTPM]":"11.7","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"22.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.4","Single Cell Type RNA - Paneth cells [nTPM]":"7.2","Single Cell Type RNA - Peritubular cells [nTPM]":"13.5","Single Cell Type RNA - Plasma cells [nTPM]":"8.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"20.8","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.9","Single Cell Type RNA - Spermatocytes [nTPM]":"54.6","Single Cell Type RNA - Spermatogonia [nTPM]":"62.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.3","Single Cell Type RNA - T-cells [nTPM]":"13.5","Single Cell Type RNA - Theca cells [nTPM]":"22.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.3","Single Cell Type RNA - Urothelial cells [nTPM]":"18.0"},{"Gene":"NUP98","Gene synonym":["NUP96","Nup98-96","Nup98-Nup96"],"Ensembl":"ENSG00000110713","Gene description":"Nucleoporin 98 and 96 precursor","Uniprot":["P52948"],"Chromosome":"11","Position":"3671083-3797792","Protein class":["Cancer-related genes","Disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Host-virus interaction","mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"118.7","Late spermatids":"158.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.71e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Tissue RNA - adipose tissue [nTPM]":"22.9","Tissue RNA - adrenal gland [nTPM]":"14.7","Tissue RNA - amygdala [nTPM]":"7.2","Tissue RNA - appendix [nTPM]":"25.1","Tissue RNA - basal ganglia [nTPM]":"8.4","Tissue RNA - bone marrow [nTPM]":"76.0","Tissue RNA - breast [nTPM]":"25.3","Tissue RNA - cerebellum [nTPM]":"15.1","Tissue RNA - cerebral cortex [nTPM]":"12.4","Tissue RNA - cervix [nTPM]":"21.8","Tissue RNA - choroid plexus [nTPM]":"13.8","Tissue RNA - colon [nTPM]":"21.1","Tissue RNA - duodenum [nTPM]":"17.8","Tissue RNA - endometrium 1 [nTPM]":"22.2","Tissue RNA - epididymis [nTPM]":"20.7","Tissue RNA - esophagus [nTPM]":"23.1","Tissue RNA - fallopian tube [nTPM]":"20.8","Tissue RNA - gallbladder [nTPM]":"21.6","Tissue RNA - heart muscle [nTPM]":"20.8","Tissue RNA - hippocampal formation [nTPM]":"7.2","Tissue RNA - hypothalamus [nTPM]":"8.8","Tissue RNA - kidney [nTPM]":"19.3","Tissue RNA - liver [nTPM]":"31.9","Tissue RNA - lung [nTPM]":"23.4","Tissue RNA - lymph node [nTPM]":"27.6","Tissue RNA - medulla oblongata [nTPM]":"9.8","Tissue RNA - midbrain [nTPM]":"10.5","Tissue RNA - ovary [nTPM]":"28.4","Tissue RNA - pancreas [nTPM]":"24.0","Tissue RNA - parathyroid gland [nTPM]":"25.7","Tissue RNA - pituitary gland [nTPM]":"16.7","Tissue RNA - placenta [nTPM]":"25.6","Tissue RNA - pons [nTPM]":"8.3","Tissue RNA - prostate [nTPM]":"21.9","Tissue RNA - rectum [nTPM]":"23.6","Tissue RNA - retina [nTPM]":"23.2","Tissue RNA - salivary gland [nTPM]":"23.3","Tissue RNA - seminal vesicle [nTPM]":"22.3","Tissue RNA - skeletal muscle [nTPM]":"41.9","Tissue RNA - skin 1 [nTPM]":"21.2","Tissue RNA - small intestine [nTPM]":"17.7","Tissue RNA - smooth muscle [nTPM]":"23.4","Tissue RNA - spinal cord [nTPM]":"7.1","Tissue RNA - spleen [nTPM]":"21.9","Tissue RNA - stomach 1 [nTPM]":"17.6","Tissue RNA - testis [nTPM]":"78.4","Tissue RNA - thalamus [nTPM]":"9.1","Tissue RNA - thymus [nTPM]":"34.4","Tissue RNA - thyroid gland [nTPM]":"29.1","Tissue RNA - tongue [nTPM]":"31.0","Tissue RNA - tonsil [nTPM]":"30.6","Tissue RNA - urinary bladder [nTPM]":"32.7","Tissue RNA - vagina [nTPM]":"18.6","Tissue RNA - white matter [nTPM]":"12.7","Cell RNA - A-431 [nTPM]":"81.2","Cell RNA - A549 [nTPM]":"63.7","Cell RNA - AF22 [nTPM]":"51.7","Cell RNA - AN3-CA [nTPM]":"54.5","Cell RNA - ASC diff [nTPM]":"54.7","Cell RNA - ASC TERT1 [nTPM]":"46.1","Cell RNA - BEWO [nTPM]":"44.5","Cell RNA - BJ [nTPM]":"57.9","Cell RNA - BJ hTERT+ [nTPM]":"67.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"78.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"69.9","Cell RNA - CACO-2 [nTPM]":"69.4","Cell RNA - CAPAN-2 [nTPM]":"97.4","Cell RNA - Daudi [nTPM]":"80.6","Cell RNA - EFO-21 [nTPM]":"26.0","Cell RNA - fHDF\/TERT166 [nTPM]":"68.6","Cell RNA - GAMG [nTPM]":"77.1","Cell RNA - HaCaT [nTPM]":"85.5","Cell RNA - HAP1 [nTPM]":"90.0","Cell RNA - HBEC3-KT [nTPM]":"56.1","Cell RNA - HBF TERT88 [nTPM]":"105.6","Cell RNA - HDLM-2 [nTPM]":"56.7","Cell RNA - HEK 293 [nTPM]":"67.0","Cell RNA - HEL [nTPM]":"86.4","Cell RNA - HeLa [nTPM]":"51.7","Cell RNA - Hep G2 [nTPM]":"48.1","Cell RNA - HHSteC [nTPM]":"46.1","Cell RNA - HL-60 [nTPM]":"111.1","Cell RNA - HMC-1 [nTPM]":"67.5","Cell RNA - HSkMC [nTPM]":"51.9","Cell RNA - hTCEpi [nTPM]":"37.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"41.8","Cell RNA - hTERT-HME1 [nTPM]":"75.2","Cell RNA - hTERT-RPE1 [nTPM]":"33.7","Cell RNA - HUVEC TERT2 [nTPM]":"61.9","Cell RNA - JURKAT [nTPM]":"88.3","Cell RNA - K-562 [nTPM]":"109.3","Cell RNA - Karpas-707 [nTPM]":"60.6","Cell RNA - LHCN-M2 [nTPM]":"82.5","Cell RNA - MCF7 [nTPM]":"33.2","Cell RNA - MOLT-4 [nTPM]":"110.2","Cell RNA - NB-4 [nTPM]":"36.3","Cell RNA - NTERA-2 [nTPM]":"64.5","Cell RNA - OE19 [nTPM]":"87.8","Cell RNA - PC-3 [nTPM]":"48.4","Cell RNA - REH [nTPM]":"65.9","Cell RNA - RH-30 [nTPM]":"62.6","Cell RNA - RPMI-8226 [nTPM]":"37.8","Cell RNA - RPTEC TERT1 [nTPM]":"43.4","Cell RNA - RT4 [nTPM]":"63.4","Cell RNA - SCLC-21H [nTPM]":"46.8","Cell RNA - SH-SY5Y [nTPM]":"31.5","Cell RNA - SiHa [nTPM]":"83.4","Cell RNA - SK-BR-3 [nTPM]":"64.9","Cell RNA - SK-MEL-30 [nTPM]":"38.1","Cell RNA - SuSa [nTPM]":"52.0","Cell RNA - T-47d [nTPM]":"40.5","Cell RNA - THP-1 [nTPM]":"43.4","Cell RNA - TIME [nTPM]":"45.9","Cell RNA - U-138 MG [nTPM]":"59.9","Cell RNA - U-2 OS [nTPM]":"51.1","Cell RNA - U-2197 [nTPM]":"67.5","Cell RNA - U-251 MG [nTPM]":"53.0","Cell RNA - U-266\/70 [nTPM]":"37.0","Cell RNA - U-266\/84 [nTPM]":"67.0","Cell RNA - U-698 [nTPM]":"83.5","Cell RNA - U-87 MG [nTPM]":"41.0","Cell RNA - U-937 [nTPM]":"46.5","Cell RNA - WM-115 [nTPM]":"64.4","Blood RNA - basophil [nTPM]":"40.5","Blood RNA - classical monocyte [nTPM]":"11.7","Blood RNA - eosinophil [nTPM]":"23.3","Blood RNA - gdT-cell [nTPM]":"15.0","Blood RNA - intermediate monocyte [nTPM]":"15.0","Blood RNA - MAIT T-cell [nTPM]":"15.1","Blood RNA - memory B-cell [nTPM]":"12.8","Blood RNA - memory CD4 T-cell [nTPM]":"14.7","Blood RNA - memory CD8 T-cell [nTPM]":"13.5","Blood RNA - myeloid DC [nTPM]":"14.3","Blood RNA - naive B-cell [nTPM]":"10.8","Blood RNA - naive CD4 T-cell [nTPM]":"16.1","Blood RNA - naive CD8 T-cell [nTPM]":"14.4","Blood RNA - neutrophil [nTPM]":"35.2","Blood RNA - NK-cell [nTPM]":"9.7","Blood RNA - non-classical monocyte [nTPM]":"9.5","Blood RNA - plasmacytoid DC [nTPM]":"3.9","Blood RNA - T-reg [nTPM]":"20.1","Blood RNA - total PBMC [nTPM]":"13.3","Brain RNA - amygdala [nTPM]":"7.2","Brain RNA - basal ganglia [nTPM]":"8.4","Brain RNA - cerebellum [nTPM]":"15.1","Brain RNA - cerebral cortex [nTPM]":"12.4","Brain RNA - hippocampal formation [nTPM]":"7.2","Brain RNA - hypothalamus [nTPM]":"8.8","Brain RNA - medulla oblongata [nTPM]":"9.8","Brain RNA - midbrain [nTPM]":"10.5","Brain RNA - pons [nTPM]":"8.3","Brain RNA - spinal cord [nTPM]":"7.1","Brain RNA - thalamus [nTPM]":"9.1","Brain RNA - white matter [nTPM]":"12.7","Single Cell Type RNA - Adipocytes [nTPM]":"24.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.2","Single Cell Type RNA - Astrocytes [nTPM]":"32.7","Single Cell Type RNA - B-cells [nTPM]":"37.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"49.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"36.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"34.7","Single Cell Type RNA - Bipolar cells [nTPM]":"14.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"28.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"20.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"22.2","Single Cell Type RNA - dendritic cells [nTPM]":"41.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"12.2","Single Cell Type RNA - Early spermatids [nTPM]":"118.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"32.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"30.4","Single Cell Type RNA - Endothelial cells [nTPM]":"22.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.5","Single Cell Type RNA - Erythroid cells [nTPM]":"42.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"43.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.5","Single Cell Type RNA - Fibroblasts [nTPM]":"22.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"42.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"62.0","Single Cell Type RNA - granulocytes [nTPM]":"18.3","Single Cell Type RNA - Granulosa cells [nTPM]":"16.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.7","Single Cell Type RNA - Hepatocytes [nTPM]":"23.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.8","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"43.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.1","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"19.8","Single Cell Type RNA - Langerhans cells [nTPM]":"51.1","Single Cell Type RNA - Late spermatids [nTPM]":"158.6","Single Cell Type RNA - Leydig cells [nTPM]":"17.1","Single Cell Type RNA - Macrophages [nTPM]":"29.3","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"25.3","Single Cell Type RNA - monocytes [nTPM]":"24.9","Single Cell Type RNA - Muller glia cells [nTPM]":"11.1","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"31.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"44.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.2","Single Cell Type RNA - Paneth cells [nTPM]":"16.1","Single Cell Type RNA - Peritubular cells [nTPM]":"14.3","Single Cell Type RNA - Plasma cells [nTPM]":"36.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"25.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.1","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"36.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.2","Single Cell Type RNA - Spermatocytes [nTPM]":"56.2","Single Cell Type RNA - Spermatogonia [nTPM]":"31.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"30.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"50.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"46.5","Single Cell Type RNA - T-cells [nTPM]":"44.5","Single Cell Type RNA - Theca cells [nTPM]":"13.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.5","Single Cell Type RNA - Urothelial cells [nTPM]":"32.5"},{"Gene":"NUS1","Gene synonym":["C6orf68","MGC7199","NgBR","TANGO14"],"Ensembl":"ENSG00000153989","Gene description":"NUS1 dehydrodolichyl diphosphate synthase subunit","Uniprot":["Q96E22"],"Chromosome":"6","Position":"117675469-117710727","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Angiogenesis","Differentiation","Lipid metabolism"],"Molecular function":["Developmental protein","Receptor","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027504"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA027504":"AB_10603124"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.99e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-2"},"Tissue RNA - adipose tissue [nTPM]":"17.8","Tissue RNA - adrenal gland [nTPM]":"20.0","Tissue RNA - amygdala [nTPM]":"12.1","Tissue RNA - appendix [nTPM]":"22.2","Tissue RNA - basal ganglia [nTPM]":"13.0","Tissue RNA - bone marrow [nTPM]":"19.4","Tissue RNA - breast [nTPM]":"22.2","Tissue RNA - cerebellum [nTPM]":"11.4","Tissue RNA - cerebral cortex [nTPM]":"15.5","Tissue RNA - cervix [nTPM]":"60.3","Tissue RNA - choroid plexus [nTPM]":"16.1","Tissue RNA - colon [nTPM]":"19.8","Tissue RNA - duodenum [nTPM]":"16.5","Tissue RNA - endometrium 1 [nTPM]":"20.6","Tissue RNA - epididymis [nTPM]":"28.4","Tissue RNA - esophagus [nTPM]":"15.7","Tissue RNA - fallopian tube [nTPM]":"18.4","Tissue RNA - gallbladder [nTPM]":"16.1","Tissue RNA - heart muscle [nTPM]":"11.7","Tissue RNA - hippocampal formation [nTPM]":"12.9","Tissue RNA - hypothalamus [nTPM]":"13.8","Tissue RNA - kidney [nTPM]":"28.4","Tissue RNA - liver [nTPM]":"31.6","Tissue RNA - lung [nTPM]":"18.2","Tissue RNA - lymph node [nTPM]":"21.4","Tissue RNA - medulla oblongata [nTPM]":"10.8","Tissue RNA - midbrain [nTPM]":"12.5","Tissue RNA - ovary [nTPM]":"16.5","Tissue RNA - pancreas [nTPM]":"20.4","Tissue RNA - parathyroid gland [nTPM]":"29.8","Tissue RNA - pituitary gland [nTPM]":"11.9","Tissue RNA - placenta [nTPM]":"21.6","Tissue RNA - pons [nTPM]":"11.9","Tissue RNA - prostate [nTPM]":"20.6","Tissue RNA - rectum [nTPM]":"20.3","Tissue RNA - retina [nTPM]":"12.5","Tissue RNA - salivary gland [nTPM]":"30.5","Tissue RNA - seminal vesicle [nTPM]":"17.6","Tissue RNA - skeletal muscle [nTPM]":"10.0","Tissue RNA - skin 1 [nTPM]":"11.1","Tissue RNA - small intestine [nTPM]":"17.6","Tissue RNA - smooth muscle [nTPM]":"18.7","Tissue RNA - spinal cord [nTPM]":"11.7","Tissue RNA - spleen [nTPM]":"17.8","Tissue RNA - stomach 1 [nTPM]":"24.2","Tissue RNA - testis [nTPM]":"12.6","Tissue RNA - thalamus [nTPM]":"13.5","Tissue RNA - thymus [nTPM]":"18.5","Tissue RNA - thyroid gland [nTPM]":"35.4","Tissue RNA - tongue [nTPM]":"12.6","Tissue RNA - tonsil [nTPM]":"20.6","Tissue RNA - urinary bladder [nTPM]":"23.5","Tissue RNA - vagina [nTPM]":"11.7","Tissue RNA - white matter [nTPM]":"12.4","Cell RNA - A-431 [nTPM]":"27.1","Cell RNA - A549 [nTPM]":"19.5","Cell RNA - AF22 [nTPM]":"41.3","Cell RNA - AN3-CA [nTPM]":"46.4","Cell RNA - ASC diff [nTPM]":"40.7","Cell RNA - ASC TERT1 [nTPM]":"52.9","Cell RNA - BEWO [nTPM]":"101.0","Cell RNA - BJ [nTPM]":"48.3","Cell RNA - BJ hTERT+ [nTPM]":"50.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"39.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"45.1","Cell RNA - CACO-2 [nTPM]":"44.6","Cell RNA - CAPAN-2 [nTPM]":"29.5","Cell RNA - Daudi [nTPM]":"63.4","Cell RNA - EFO-21 [nTPM]":"51.1","Cell RNA - fHDF\/TERT166 [nTPM]":"44.7","Cell RNA - GAMG [nTPM]":"50.0","Cell RNA - HaCaT [nTPM]":"24.0","Cell RNA - HAP1 [nTPM]":"62.1","Cell RNA - HBEC3-KT [nTPM]":"47.2","Cell RNA - HBF TERT88 [nTPM]":"73.0","Cell RNA - HDLM-2 [nTPM]":"47.9","Cell RNA - HEK 293 [nTPM]":"57.0","Cell RNA - HEL [nTPM]":"72.8","Cell RNA - HeLa [nTPM]":"31.5","Cell RNA - Hep G2 [nTPM]":"80.2","Cell RNA - HHSteC [nTPM]":"62.6","Cell RNA - HL-60 [nTPM]":"92.8","Cell RNA - HMC-1 [nTPM]":"41.2","Cell RNA - HSkMC [nTPM]":"46.6","Cell RNA - hTCEpi [nTPM]":"52.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"43.3","Cell RNA - hTERT-HME1 [nTPM]":"87.7","Cell RNA - hTERT-RPE1 [nTPM]":"40.3","Cell RNA - HUVEC TERT2 [nTPM]":"41.3","Cell RNA - JURKAT [nTPM]":"46.5","Cell RNA - K-562 [nTPM]":"88.4","Cell RNA - Karpas-707 [nTPM]":"54.9","Cell RNA - LHCN-M2 [nTPM]":"59.7","Cell RNA - MCF7 [nTPM]":"30.5","Cell RNA - MOLT-4 [nTPM]":"43.9","Cell RNA - NB-4 [nTPM]":"58.8","Cell RNA - NTERA-2 [nTPM]":"48.0","Cell RNA - OE19 [nTPM]":"36.9","Cell RNA - PC-3 [nTPM]":"35.3","Cell RNA - REH [nTPM]":"41.7","Cell RNA - RH-30 [nTPM]":"29.7","Cell RNA - RPMI-8226 [nTPM]":"45.7","Cell RNA - RPTEC TERT1 [nTPM]":"79.0","Cell RNA - RT4 [nTPM]":"26.6","Cell RNA - SCLC-21H [nTPM]":"48.7","Cell RNA - SH-SY5Y [nTPM]":"38.5","Cell RNA - SiHa [nTPM]":"29.1","Cell RNA - SK-BR-3 [nTPM]":"37.4","Cell RNA - SK-MEL-30 [nTPM]":"36.9","Cell RNA - SuSa [nTPM]":"45.6","Cell RNA - T-47d [nTPM]":"23.8","Cell RNA - THP-1 [nTPM]":"95.9","Cell RNA - TIME [nTPM]":"36.4","Cell RNA - U-138 MG [nTPM]":"24.3","Cell RNA - U-2 OS [nTPM]":"30.1","Cell RNA - U-2197 [nTPM]":"39.2","Cell RNA - U-251 MG [nTPM]":"70.5","Cell RNA - U-266\/70 [nTPM]":"75.6","Cell RNA - U-266\/84 [nTPM]":"60.8","Cell RNA - U-698 [nTPM]":"66.8","Cell RNA - U-87 MG [nTPM]":"57.6","Cell RNA - U-937 [nTPM]":"70.0","Cell RNA - WM-115 [nTPM]":"49.7","Blood RNA - basophil [nTPM]":"1.9","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"0.8","Blood RNA - gdT-cell [nTPM]":"1.3","Blood RNA - intermediate monocyte [nTPM]":"1.4","Blood RNA - MAIT T-cell [nTPM]":"1.9","Blood RNA - memory B-cell [nTPM]":"1.1","Blood RNA - memory CD4 T-cell [nTPM]":"1.6","Blood RNA - memory CD8 T-cell [nTPM]":"1.8","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"1.7","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"1.9","Blood RNA - non-classical monocyte [nTPM]":"2.5","Blood RNA - plasmacytoid DC [nTPM]":"3.8","Blood RNA - T-reg [nTPM]":"1.7","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"12.1","Brain RNA - basal ganglia [nTPM]":"13.0","Brain RNA - cerebellum [nTPM]":"11.4","Brain RNA - cerebral cortex [nTPM]":"15.5","Brain RNA - hippocampal formation [nTPM]":"12.9","Brain RNA - hypothalamus [nTPM]":"13.8","Brain RNA - medulla oblongata [nTPM]":"10.8","Brain RNA - midbrain [nTPM]":"12.5","Brain RNA - pons [nTPM]":"11.9","Brain RNA - spinal cord [nTPM]":"11.7","Brain RNA - thalamus [nTPM]":"13.5","Brain RNA - white matter [nTPM]":"12.4","Single Cell Type RNA - Adipocytes [nTPM]":"18.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"22.3","Single Cell Type RNA - Astrocytes [nTPM]":"30.3","Single Cell Type RNA - B-cells [nTPM]":"28.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"60.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"41.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"32.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.4","Single Cell Type RNA - Bipolar cells [nTPM]":"15.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"24.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"26.8","Single Cell Type RNA - dendritic cells [nTPM]":"38.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"26.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"27.4","Single Cell Type RNA - Ductal cells [nTPM]":"23.4","Single Cell Type RNA - Early spermatids [nTPM]":"16.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"28.9","Single Cell Type RNA - Endothelial cells [nTPM]":"24.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"19.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"33.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"63.6","Single Cell Type RNA - Fibroblasts [nTPM]":"22.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"38.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.4","Single Cell Type RNA - granulocytes [nTPM]":"31.1","Single Cell Type RNA - Granulosa cells [nTPM]":"15.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.2","Single Cell Type RNA - Hepatocytes [nTPM]":"39.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"35.3","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"29.3","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"37.0","Single Cell Type RNA - Langerhans cells [nTPM]":"42.2","Single Cell Type RNA - Late spermatids [nTPM]":"14.0","Single Cell Type RNA - Leydig cells [nTPM]":"18.0","Single Cell Type RNA - Macrophages [nTPM]":"30.2","Single Cell Type RNA - Melanocytes [nTPM]":"32.0","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"28.4","Single Cell Type RNA - Muller glia cells [nTPM]":"8.3","Single Cell Type RNA - NK-cells [nTPM]":"24.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"35.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"36.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"37.4","Single Cell Type RNA - Paneth cells [nTPM]":"22.7","Single Cell Type RNA - Peritubular cells [nTPM]":"20.3","Single Cell Type RNA - Plasma cells [nTPM]":"57.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"73.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"33.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"25.9","Single Cell Type RNA - Spermatocytes [nTPM]":"24.9","Single Cell Type RNA - Spermatogonia [nTPM]":"25.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"56.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"57.9","Single Cell Type RNA - T-cells [nTPM]":"26.2","Single Cell Type RNA - Theca cells [nTPM]":"14.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.1","Single Cell Type RNA - Urothelial cells [nTPM]":"77.5"},{"Gene":"NXN","Gene synonym":["FLJ12614","NRX"],"Ensembl":"ENSG00000167693","Gene description":"Nucleoredoxin","Uniprot":["Q6DKJ4"],"Chromosome":"17","Position":"799310-979776","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Differentiation","Wnt signaling pathway"],"Molecular function":["Developmental protein","Oxidoreductase"],"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"99.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"91.5","Microglial cells":"87.1","Urothelial cells":"59.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"100.7","HHSteC":"106.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023566"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA023566":"AB_1854737"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-3"},"Tissue RNA - adipose tissue [nTPM]":"16.9","Tissue RNA - adrenal gland [nTPM]":"7.5","Tissue RNA - amygdala [nTPM]":"14.5","Tissue RNA - appendix [nTPM]":"8.7","Tissue RNA - basal ganglia [nTPM]":"13.1","Tissue RNA - bone marrow [nTPM]":"1.1","Tissue RNA - breast [nTPM]":"19.0","Tissue RNA - cerebellum [nTPM]":"12.1","Tissue RNA - cerebral cortex [nTPM]":"15.0","Tissue RNA - cervix [nTPM]":"41.3","Tissue RNA - choroid plexus [nTPM]":"21.9","Tissue RNA - colon [nTPM]":"70.0","Tissue RNA - duodenum [nTPM]":"5.4","Tissue RNA - endometrium 1 [nTPM]":"47.2","Tissue RNA - epididymis [nTPM]":"11.6","Tissue RNA - esophagus [nTPM]":"27.2","Tissue RNA - fallopian tube [nTPM]":"29.1","Tissue RNA - gallbladder [nTPM]":"13.7","Tissue RNA - heart muscle [nTPM]":"16.0","Tissue RNA - hippocampal formation [nTPM]":"13.5","Tissue RNA - hypothalamus [nTPM]":"13.2","Tissue RNA - kidney [nTPM]":"14.4","Tissue RNA - liver [nTPM]":"9.5","Tissue RNA - lung [nTPM]":"24.6","Tissue RNA - lymph node [nTPM]":"5.0","Tissue RNA - medulla oblongata [nTPM]":"13.6","Tissue RNA - midbrain [nTPM]":"14.9","Tissue RNA - ovary [nTPM]":"14.8","Tissue RNA - pancreas [nTPM]":"33.6","Tissue RNA - parathyroid gland [nTPM]":"2.6","Tissue RNA - pituitary gland [nTPM]":"6.8","Tissue RNA - placenta [nTPM]":"14.5","Tissue RNA - pons [nTPM]":"14.0","Tissue RNA - prostate [nTPM]":"39.7","Tissue RNA - rectum [nTPM]":"4.6","Tissue RNA - retina [nTPM]":"8.9","Tissue RNA - salivary gland [nTPM]":"20.7","Tissue RNA - seminal vesicle [nTPM]":"25.0","Tissue RNA - skeletal muscle [nTPM]":"99.2","Tissue RNA - skin 1 [nTPM]":"24.9","Tissue RNA - small intestine [nTPM]":"19.8","Tissue RNA - smooth muscle [nTPM]":"23.1","Tissue RNA - spinal cord [nTPM]":"12.8","Tissue RNA - spleen [nTPM]":"6.4","Tissue RNA - stomach 1 [nTPM]":"28.3","Tissue RNA - testis [nTPM]":"9.6","Tissue RNA - thalamus [nTPM]":"17.1","Tissue RNA - thymus [nTPM]":"13.1","Tissue RNA - thyroid gland [nTPM]":"12.9","Tissue RNA - tongue [nTPM]":"35.7","Tissue RNA - tonsil [nTPM]":"13.8","Tissue RNA - urinary bladder [nTPM]":"43.4","Tissue RNA - vagina [nTPM]":"42.5","Tissue RNA - white matter [nTPM]":"12.3","Cell RNA - A-431 [nTPM]":"14.3","Cell RNA - A549 [nTPM]":"21.2","Cell RNA - AF22 [nTPM]":"81.5","Cell RNA - AN3-CA [nTPM]":"52.8","Cell RNA - ASC diff [nTPM]":"5.3","Cell RNA - ASC TERT1 [nTPM]":"1.1","Cell RNA - BEWO [nTPM]":"4.5","Cell RNA - BJ [nTPM]":"44.6","Cell RNA - BJ hTERT+ [nTPM]":"29.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"46.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"73.3","Cell RNA - CACO-2 [nTPM]":"50.4","Cell RNA - CAPAN-2 [nTPM]":"14.8","Cell RNA - Daudi [nTPM]":"0.6","Cell RNA - EFO-21 [nTPM]":"83.6","Cell RNA - fHDF\/TERT166 [nTPM]":"57.5","Cell RNA - GAMG [nTPM]":"10.8","Cell RNA - HaCaT [nTPM]":"100.7","Cell RNA - HAP1 [nTPM]":"52.9","Cell RNA - HBEC3-KT [nTPM]":"83.2","Cell RNA - HBF TERT88 [nTPM]":"36.3","Cell RNA - HDLM-2 [nTPM]":"0.6","Cell RNA - HEK 293 [nTPM]":"30.9","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"12.7","Cell RNA - Hep G2 [nTPM]":"44.8","Cell RNA - HHSteC [nTPM]":"106.1","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"2.3","Cell RNA - HSkMC [nTPM]":"32.2","Cell RNA - hTCEpi [nTPM]":"75.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.0","Cell RNA - hTERT-HME1 [nTPM]":"36.0","Cell RNA - hTERT-RPE1 [nTPM]":"9.3","Cell RNA - HUVEC TERT2 [nTPM]":"41.9","Cell RNA - JURKAT [nTPM]":"11.3","Cell RNA - K-562 [nTPM]":"7.4","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"12.3","Cell RNA - MCF7 [nTPM]":"5.8","Cell RNA - MOLT-4 [nTPM]":"2.9","Cell RNA - NB-4 [nTPM]":"1.0","Cell RNA - NTERA-2 [nTPM]":"39.2","Cell RNA - OE19 [nTPM]":"42.3","Cell RNA - PC-3 [nTPM]":"1.4","Cell RNA - REH [nTPM]":"6.2","Cell RNA - RH-30 [nTPM]":"2.1","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"32.9","Cell RNA - RT4 [nTPM]":"20.6","Cell RNA - SCLC-21H [nTPM]":"20.9","Cell RNA - SH-SY5Y [nTPM]":"13.6","Cell RNA - SiHa [nTPM]":"21.1","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"1.1","Cell RNA - SuSa [nTPM]":"50.3","Cell RNA - T-47d [nTPM]":"14.9","Cell RNA - THP-1 [nTPM]":"13.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"1.0","Cell RNA - U-2 OS [nTPM]":"19.1","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"12.5","Cell RNA - U-266\/70 [nTPM]":"7.5","Cell RNA - U-266\/84 [nTPM]":"5.2","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"1.7","Cell RNA - WM-115 [nTPM]":"0.7","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"14.5","Brain RNA - basal ganglia [nTPM]":"13.1","Brain RNA - cerebellum [nTPM]":"12.1","Brain RNA - cerebral cortex [nTPM]":"15.0","Brain RNA - hippocampal formation [nTPM]":"13.5","Brain RNA - hypothalamus [nTPM]":"13.2","Brain RNA - medulla oblongata [nTPM]":"13.6","Brain RNA - midbrain [nTPM]":"14.9","Brain RNA - pons [nTPM]":"14.0","Brain RNA - spinal cord [nTPM]":"12.8","Brain RNA - thalamus [nTPM]":"17.1","Brain RNA - white matter [nTPM]":"12.3","Single Cell Type RNA - Adipocytes [nTPM]":"36.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.7","Single Cell Type RNA - Astrocytes [nTPM]":"13.4","Single Cell Type RNA - B-cells [nTPM]":"0.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"53.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.0","Single Cell Type RNA - Bipolar cells [nTPM]":"2.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"13.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.5","Single Cell Type RNA - Early spermatids [nTPM]":"25.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"52.1","Single Cell Type RNA - Endothelial cells [nTPM]":"34.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"24.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"23.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.6","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"1.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"8.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.3","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"8.8","Single Cell Type RNA - Late spermatids [nTPM]":"91.5","Single Cell Type RNA - Leydig cells [nTPM]":"15.5","Single Cell Type RNA - Macrophages [nTPM]":"1.9","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"87.1","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"11.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"23.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"36.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.2","Single Cell Type RNA - Spermatocytes [nTPM]":"13.1","Single Cell Type RNA - Spermatogonia [nTPM]":"10.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"1.5","Single Cell Type RNA - Theca cells [nTPM]":"27.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"59.0"},{"Gene":"OAT","Gene synonym":["HOGA"],"Ensembl":"ENSG00000065154","Gene description":"Ornithine aminotransferase","Uniprot":["P04181"],"Chromosome":"10","Position":"124397303-124418976","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Aminotransferase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"781.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"1222.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033576","HPA040098","HPA064742"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB033576":"AB_2298892","HPA040098":"AB_10793955","HPA064742":"AB_2685343"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Tissue RNA - adipose tissue [nTPM]":"60.0","Tissue RNA - adrenal gland [nTPM]":"119.6","Tissue RNA - amygdala [nTPM]":"69.4","Tissue RNA - appendix [nTPM]":"40.8","Tissue RNA - basal ganglia [nTPM]":"71.2","Tissue RNA - bone marrow [nTPM]":"106.4","Tissue RNA - breast [nTPM]":"150.1","Tissue RNA - cerebellum [nTPM]":"74.6","Tissue RNA - cerebral cortex [nTPM]":"97.4","Tissue RNA - cervix [nTPM]":"99.7","Tissue RNA - choroid plexus [nTPM]":"75.4","Tissue RNA - colon [nTPM]":"75.6","Tissue RNA - duodenum [nTPM]":"750.0","Tissue RNA - endometrium 1 [nTPM]":"82.5","Tissue RNA - epididymis [nTPM]":"63.7","Tissue RNA - esophagus [nTPM]":"105.0","Tissue RNA - fallopian tube [nTPM]":"56.0","Tissue RNA - gallbladder [nTPM]":"68.7","Tissue RNA - heart muscle [nTPM]":"52.3","Tissue RNA - hippocampal formation [nTPM]":"71.2","Tissue RNA - hypothalamus [nTPM]":"78.7","Tissue RNA - kidney [nTPM]":"114.6","Tissue RNA - liver [nTPM]":"162.5","Tissue RNA - lung [nTPM]":"42.7","Tissue RNA - lymph node [nTPM]":"38.1","Tissue RNA - medulla oblongata [nTPM]":"76.5","Tissue RNA - midbrain [nTPM]":"72.0","Tissue RNA - ovary [nTPM]":"77.0","Tissue RNA - pancreas [nTPM]":"36.1","Tissue RNA - parathyroid gland [nTPM]":"46.1","Tissue RNA - pituitary gland [nTPM]":"53.5","Tissue RNA - placenta [nTPM]":"65.0","Tissue RNA - pons [nTPM]":"85.2","Tissue RNA - prostate [nTPM]":"74.3","Tissue RNA - rectum [nTPM]":"67.2","Tissue RNA - retina [nTPM]":"51.1","Tissue RNA - salivary gland [nTPM]":"225.4","Tissue RNA - seminal vesicle [nTPM]":"94.6","Tissue RNA - skeletal muscle [nTPM]":"58.2","Tissue RNA - skin 1 [nTPM]":"71.6","Tissue RNA - small intestine [nTPM]":"781.8","Tissue RNA - smooth muscle [nTPM]":"97.8","Tissue RNA - spinal cord [nTPM]":"73.6","Tissue RNA - spleen [nTPM]":"34.1","Tissue RNA - stomach 1 [nTPM]":"70.1","Tissue RNA - testis [nTPM]":"56.2","Tissue RNA - thalamus [nTPM]":"73.3","Tissue RNA - thymus [nTPM]":"30.2","Tissue RNA - thyroid gland [nTPM]":"67.7","Tissue RNA - tongue [nTPM]":"60.0","Tissue RNA - tonsil [nTPM]":"69.1","Tissue RNA - urinary bladder [nTPM]":"58.9","Tissue RNA - vagina [nTPM]":"63.8","Tissue RNA - white matter [nTPM]":"81.7","Cell RNA - A-431 [nTPM]":"241.5","Cell RNA - A549 [nTPM]":"42.8","Cell RNA - AF22 [nTPM]":"27.5","Cell RNA - AN3-CA [nTPM]":"98.7","Cell RNA - ASC diff [nTPM]":"272.4","Cell RNA - ASC TERT1 [nTPM]":"260.8","Cell RNA - BEWO [nTPM]":"93.4","Cell RNA - BJ [nTPM]":"142.2","Cell RNA - BJ hTERT+ [nTPM]":"288.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"124.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"135.2","Cell RNA - CACO-2 [nTPM]":"110.5","Cell RNA - CAPAN-2 [nTPM]":"30.8","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"101.0","Cell RNA - fHDF\/TERT166 [nTPM]":"241.8","Cell RNA - GAMG [nTPM]":"118.0","Cell RNA - HaCaT [nTPM]":"249.4","Cell RNA - HAP1 [nTPM]":"126.5","Cell RNA - HBEC3-KT [nTPM]":"265.7","Cell RNA - HBF TERT88 [nTPM]":"134.0","Cell RNA - HDLM-2 [nTPM]":"42.4","Cell RNA - HEK 293 [nTPM]":"174.9","Cell RNA - HEL [nTPM]":"268.1","Cell RNA - HeLa [nTPM]":"28.1","Cell RNA - Hep G2 [nTPM]":"82.7","Cell RNA - HHSteC [nTPM]":"139.9","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"169.3","Cell RNA - HSkMC [nTPM]":"172.1","Cell RNA - hTCEpi [nTPM]":"134.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"111.9","Cell RNA - hTERT-HME1 [nTPM]":"129.5","Cell RNA - hTERT-RPE1 [nTPM]":"204.9","Cell RNA - HUVEC TERT2 [nTPM]":"147.1","Cell RNA - JURKAT [nTPM]":"48.4","Cell RNA - K-562 [nTPM]":"470.8","Cell RNA - Karpas-707 [nTPM]":"50.0","Cell RNA - LHCN-M2 [nTPM]":"175.5","Cell RNA - MCF7 [nTPM]":"62.6","Cell RNA - MOLT-4 [nTPM]":"72.1","Cell RNA - NB-4 [nTPM]":"15.3","Cell RNA - NTERA-2 [nTPM]":"55.1","Cell RNA - OE19 [nTPM]":"73.2","Cell RNA - PC-3 [nTPM]":"59.6","Cell RNA - REH [nTPM]":"66.3","Cell RNA - RH-30 [nTPM]":"104.5","Cell RNA - RPMI-8226 [nTPM]":"65.3","Cell RNA - RPTEC TERT1 [nTPM]":"119.8","Cell RNA - RT4 [nTPM]":"3.9","Cell RNA - SCLC-21H [nTPM]":"57.3","Cell RNA - SH-SY5Y [nTPM]":"60.9","Cell RNA - SiHa [nTPM]":"89.7","Cell RNA - SK-BR-3 [nTPM]":"235.1","Cell RNA - SK-MEL-30 [nTPM]":"209.5","Cell RNA - SuSa [nTPM]":"156.6","Cell RNA - T-47d [nTPM]":"78.6","Cell RNA - THP-1 [nTPM]":"65.8","Cell RNA - TIME [nTPM]":"114.3","Cell RNA - U-138 MG [nTPM]":"70.5","Cell RNA - U-2 OS [nTPM]":"65.3","Cell RNA - U-2197 [nTPM]":"117.9","Cell RNA - U-251 MG [nTPM]":"90.2","Cell RNA - U-266\/70 [nTPM]":"42.4","Cell RNA - U-266\/84 [nTPM]":"47.6","Cell RNA - U-698 [nTPM]":"64.6","Cell RNA - U-87 MG [nTPM]":"97.4","Cell RNA - U-937 [nTPM]":"72.0","Cell RNA - WM-115 [nTPM]":"34.4","Blood RNA - basophil [nTPM]":"38.0","Blood RNA - classical monocyte [nTPM]":"39.6","Blood RNA - eosinophil [nTPM]":"36.0","Blood RNA - gdT-cell [nTPM]":"28.8","Blood RNA - intermediate monocyte [nTPM]":"35.3","Blood RNA - MAIT T-cell [nTPM]":"31.2","Blood RNA - memory B-cell [nTPM]":"15.2","Blood RNA - memory CD4 T-cell [nTPM]":"24.0","Blood RNA - memory CD8 T-cell [nTPM]":"30.5","Blood RNA - myeloid DC [nTPM]":"44.3","Blood RNA - naive B-cell [nTPM]":"16.2","Blood RNA - naive CD4 T-cell [nTPM]":"29.5","Blood RNA - naive CD8 T-cell [nTPM]":"29.8","Blood RNA - neutrophil [nTPM]":"40.0","Blood RNA - NK-cell [nTPM]":"16.9","Blood RNA - non-classical monocyte [nTPM]":"37.2","Blood RNA - plasmacytoid DC [nTPM]":"9.4","Blood RNA - T-reg [nTPM]":"24.6","Blood RNA - total PBMC [nTPM]":"29.6","Brain RNA - amygdala [nTPM]":"69.4","Brain RNA - basal ganglia [nTPM]":"71.2","Brain RNA - cerebellum [nTPM]":"74.6","Brain RNA - cerebral cortex [nTPM]":"97.4","Brain RNA - hippocampal formation [nTPM]":"71.2","Brain RNA - hypothalamus [nTPM]":"78.7","Brain RNA - medulla oblongata [nTPM]":"76.5","Brain RNA - midbrain [nTPM]":"72.0","Brain RNA - pons [nTPM]":"85.2","Brain RNA - spinal cord [nTPM]":"73.6","Brain RNA - thalamus [nTPM]":"73.3","Brain RNA - white matter [nTPM]":"81.7","Single Cell Type RNA - Adipocytes [nTPM]":"49.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"49.7","Single Cell Type RNA - Astrocytes [nTPM]":"37.9","Single Cell Type RNA - B-cells [nTPM]":"44.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"151.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"144.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"362.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"185.5","Single Cell Type RNA - Bipolar cells [nTPM]":"35.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"154.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"163.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"21.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"182.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"35.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"120.8","Single Cell Type RNA - dendritic cells [nTPM]":"80.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"38.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"90.1","Single Cell Type RNA - Ductal cells [nTPM]":"34.6","Single Cell Type RNA - Early spermatids [nTPM]":"30.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"37.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"90.4","Single Cell Type RNA - Endothelial cells [nTPM]":"37.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"43.1","Single Cell Type RNA - Erythroid cells [nTPM]":"317.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"31.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"90.5","Single Cell Type RNA - Fibroblasts [nTPM]":"124.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"55.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"40.6","Single Cell Type RNA - granulocytes [nTPM]":"43.8","Single Cell Type RNA - Granulosa cells [nTPM]":"32.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"37.5","Single Cell Type RNA - Hepatocytes [nTPM]":"152.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"66.2","Single Cell Type RNA - Horizontal cells [nTPM]":"43.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"33.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"104.1","Single Cell Type RNA - Ionocytes [nTPM]":"197.4","Single Cell Type RNA - Kupffer cells [nTPM]":"31.8","Single Cell Type RNA - Langerhans cells [nTPM]":"68.1","Single Cell Type RNA - Late spermatids [nTPM]":"15.2","Single Cell Type RNA - Leydig cells [nTPM]":"104.1","Single Cell Type RNA - Macrophages [nTPM]":"56.7","Single Cell Type RNA - Melanocytes [nTPM]":"85.4","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"34.8","Single Cell Type RNA - Muller glia cells [nTPM]":"37.4","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"22.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"41.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.6","Single Cell Type RNA - Paneth cells [nTPM]":"74.6","Single Cell Type RNA - Peritubular cells [nTPM]":"120.0","Single Cell Type RNA - Plasma cells [nTPM]":"32.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"82.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1222.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"196.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"76.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.4","Single Cell Type RNA - Sertoli cells [nTPM]":"78.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"106.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"115.1","Single Cell Type RNA - Spermatocytes [nTPM]":"46.3","Single Cell Type RNA - Spermatogonia [nTPM]":"33.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"161.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"126.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"48.2","Single Cell Type RNA - T-cells [nTPM]":"65.0","Single Cell Type RNA - Theca cells [nTPM]":"92.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"214.5","Single Cell Type RNA - Urothelial cells [nTPM]":"82.2"},{"Gene":"OBSCN","Gene synonym":["ARHGEF30","KIAA1556","KIAA1639","UNC89"],"Ensembl":"ENSG00000154358","Gene description":"Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF","Uniprot":["Q5VST9"],"Chromosome":"1","Position":"228208044-228378876","Protein class":["Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Differentiation"],"Molecular function":["Calmodulin-binding","Developmental protein","Kinase","Muscle protein","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"skeletal muscle":"481.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Cardiomyocytes":"155.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"10.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021186","HPA065801"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4500000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 37: Myocytes - Muscle contraction","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA021186":"AB_1854761","HPA065801":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.47e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.64e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.5","Tissue RNA - adrenal gland [nTPM]":"2.5","Tissue RNA - amygdala [nTPM]":"2.4","Tissue RNA - appendix [nTPM]":"1.4","Tissue RNA - basal ganglia [nTPM]":"18.4","Tissue RNA - bone marrow [nTPM]":"1.6","Tissue RNA - breast [nTPM]":"3.7","Tissue RNA - cerebellum [nTPM]":"10.4","Tissue RNA - cerebral cortex [nTPM]":"4.4","Tissue RNA - cervix [nTPM]":"8.1","Tissue RNA - choroid plexus [nTPM]":"18.1","Tissue RNA - colon [nTPM]":"5.2","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"3.7","Tissue RNA - epididymis [nTPM]":"1.8","Tissue RNA - esophagus [nTPM]":"4.6","Tissue RNA - fallopian tube [nTPM]":"5.1","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"78.5","Tissue RNA - hippocampal formation [nTPM]":"0.9","Tissue RNA - hypothalamus [nTPM]":"2.7","Tissue RNA - kidney [nTPM]":"6.6","Tissue RNA - liver [nTPM]":"1.3","Tissue RNA - lung [nTPM]":"8.9","Tissue RNA - lymph node [nTPM]":"2.1","Tissue RNA - medulla oblongata [nTPM]":"4.3","Tissue RNA - midbrain [nTPM]":"2.7","Tissue RNA - ovary [nTPM]":"8.6","Tissue RNA - pancreas [nTPM]":"5.4","Tissue RNA - parathyroid gland [nTPM]":"1.1","Tissue RNA - pituitary gland [nTPM]":"13.6","Tissue RNA - placenta [nTPM]":"0.9","Tissue RNA - pons [nTPM]":"2.4","Tissue RNA - prostate [nTPM]":"9.9","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"0.8","Tissue RNA - salivary gland [nTPM]":"9.4","Tissue RNA - seminal vesicle [nTPM]":"1.7","Tissue RNA - skeletal muscle [nTPM]":"481.3","Tissue RNA - skin 1 [nTPM]":"4.7","Tissue RNA - small intestine [nTPM]":"5.4","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"9.3","Tissue RNA - stomach 1 [nTPM]":"5.2","Tissue RNA - testis [nTPM]":"1.9","Tissue RNA - thalamus [nTPM]":"6.3","Tissue RNA - thymus [nTPM]":"4.9","Tissue RNA - thyroid gland [nTPM]":"7.5","Tissue RNA - tongue [nTPM]":"112.8","Tissue RNA - tonsil [nTPM]":"1.3","Tissue RNA - urinary bladder [nTPM]":"3.2","Tissue RNA - vagina [nTPM]":"7.4","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"1.7","Cell RNA - A549 [nTPM]":"2.8","Cell RNA - AF22 [nTPM]":"3.6","Cell RNA - AN3-CA [nTPM]":"3.7","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"4.6","Cell RNA - BJ [nTPM]":"1.6","Cell RNA - BJ hTERT+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.4","Cell RNA - CACO-2 [nTPM]":"2.1","Cell RNA - CAPAN-2 [nTPM]":"1.3","Cell RNA - Daudi [nTPM]":"3.2","Cell RNA - EFO-21 [nTPM]":"5.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.7","Cell RNA - GAMG [nTPM]":"0.7","Cell RNA - HaCaT [nTPM]":"2.1","Cell RNA - HAP1 [nTPM]":"1.3","Cell RNA - HBEC3-KT [nTPM]":"2.2","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"2.0","Cell RNA - HEK 293 [nTPM]":"3.4","Cell RNA - HEL [nTPM]":"1.7","Cell RNA - HeLa [nTPM]":"10.5","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"1.2","Cell RNA - HL-60 [nTPM]":"2.4","Cell RNA - HMC-1 [nTPM]":"2.2","Cell RNA - HSkMC [nTPM]":"1.4","Cell RNA - hTCEpi [nTPM]":"0.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.4","Cell RNA - hTERT-HME1 [nTPM]":"0.5","Cell RNA - hTERT-RPE1 [nTPM]":"5.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.5","Cell RNA - JURKAT [nTPM]":"7.0","Cell RNA - K-562 [nTPM]":"3.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.3","Cell RNA - MCF7 [nTPM]":"1.8","Cell RNA - MOLT-4 [nTPM]":"3.3","Cell RNA - NB-4 [nTPM]":"3.5","Cell RNA - NTERA-2 [nTPM]":"4.9","Cell RNA - OE19 [nTPM]":"0.6","Cell RNA - PC-3 [nTPM]":"2.1","Cell RNA - REH [nTPM]":"4.4","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.9","Cell RNA - RPTEC TERT1 [nTPM]":"1.8","Cell RNA - RT4 [nTPM]":"1.4","Cell RNA - SCLC-21H [nTPM]":"1.7","Cell RNA - SH-SY5Y [nTPM]":"6.3","Cell RNA - SiHa [nTPM]":"0.6","Cell RNA - SK-BR-3 [nTPM]":"3.9","Cell RNA - SK-MEL-30 [nTPM]":"1.0","Cell RNA - SuSa [nTPM]":"0.8","Cell RNA - T-47d [nTPM]":"3.4","Cell RNA - THP-1 [nTPM]":"4.0","Cell RNA - TIME [nTPM]":"1.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"5.1","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.5","Cell RNA - U-266\/70 [nTPM]":"2.5","Cell RNA - U-266\/84 [nTPM]":"0.5","Cell RNA - U-698 [nTPM]":"4.7","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.8","Cell RNA - WM-115 [nTPM]":"2.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"2.4","Brain RNA - basal ganglia [nTPM]":"18.4","Brain RNA - cerebellum [nTPM]":"10.4","Brain RNA - cerebral cortex [nTPM]":"4.4","Brain RNA - hippocampal formation [nTPM]":"0.9","Brain RNA - hypothalamus [nTPM]":"2.7","Brain RNA - medulla oblongata [nTPM]":"4.3","Brain RNA - midbrain [nTPM]":"2.7","Brain RNA - pons [nTPM]":"2.4","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"6.3","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"1.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.5","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"2.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.9","Single Cell Type RNA - Bipolar cells [nTPM]":"4.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"155.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"4.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"1.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"3.6","Single Cell Type RNA - Early spermatids [nTPM]":"4.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.7","Single Cell Type RNA - Endothelial cells [nTPM]":"3.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"3.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"5.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.3","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.7","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1.0","Single Cell Type RNA - Late spermatids [nTPM]":"4.5","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"1.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"0.5","Single Cell Type RNA - Muller glia cells [nTPM]":"7.9","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.8","Single Cell Type RNA - Paneth cells [nTPM]":"1.1","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"1.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"4.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - T-cells [nTPM]":"5.4","Single Cell Type RNA - Theca cells [nTPM]":"6.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.2","Single Cell Type RNA - Urothelial cells [nTPM]":"3.6"},{"Gene":"OCA2","Gene synonym":["BEY","BEY1","BEY2","D15S12","EYCL","EYCL2","EYCL3","P"],"Ensembl":"ENSG00000104044","Gene description":"OCA2 melanosomal transmembrane protein","Uniprot":["Q04671"],"Chromosome":"15","Position":"27754875-28099315","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Albinism","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"choroid plexus":"28.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"30.9","Inhibitory neurons":"40.8","Melanocytes":"42.7","Peritubular cells":"14.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"17","RNA cancer specific FPKM":{"melanoma":"19.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"SK-MEL-30":"24.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036402"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA036402":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"1.8","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"1.8","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"1.8","Tissue RNA - cervix [nTPM]":"1.2","Tissue RNA - choroid plexus [nTPM]":"28.1","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"2.2","Tissue RNA - fallopian tube [nTPM]":"1.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"1.4","Tissue RNA - hypothalamus [nTPM]":"1.8","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.6","Tissue RNA - lymph node [nTPM]":"1.8","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"1.5","Tissue RNA - pons [nTPM]":"0.6","Tissue RNA - prostate [nTPM]":"0.6","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.8","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"6.4","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"1.1","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"1.9","Tissue RNA - thalamus [nTPM]":"2.4","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"4.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.7","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"2.4","Tissue RNA - white matter [nTPM]":"1.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.6","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.6","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"2.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.5","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"5.6","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"24.6","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.8","Brain RNA - basal ganglia [nTPM]":"1.8","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"1.8","Brain RNA - hippocampal formation [nTPM]":"1.4","Brain RNA - hypothalamus [nTPM]":"1.8","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"0.6","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"2.4","Brain RNA - white matter [nTPM]":"1.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"4.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"30.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"40.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.9","Single Cell Type RNA - Late spermatids [nTPM]":"3.0","Single Cell Type RNA - Leydig cells [nTPM]":"9.3","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"42.7","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"14.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.8","Single Cell Type RNA - Spermatocytes [nTPM]":"4.2","Single Cell Type RNA - Spermatogonia [nTPM]":"4.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"OCLN","Gene synonym":["PPP1R115"],"Ensembl":"ENSG00000197822","Gene description":"Occludin","Uniprot":["Q16625"],"Chromosome":"5","Position":"69492292-69558104","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"thyroid gland":"31.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"109.0","Glandular and luminal cells":"119.7","Urothelial cells":"224.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"2.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"2.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"23.3","CAPAN-2":"39.8","HaCaT":"33.4","RPTEC TERT1":"25.7","SK-BR-3":"27.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005933","CAB013075","CAB068212","CAB068213","CAB068214"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"CAB013075":"AB_2533101","CAB068212":"AB_2665711","CAB068213":"AB_2665712","CAB068214":"AB_2665713","HPA005933":"AB_1079520"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.59e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.2","Tissue RNA - adrenal gland [nTPM]":"0.7","Tissue RNA - amygdala [nTPM]":"6.2","Tissue RNA - appendix [nTPM]":"1.6","Tissue RNA - basal ganglia [nTPM]":"6.5","Tissue RNA - bone marrow [nTPM]":"1.8","Tissue RNA - breast [nTPM]":"7.8","Tissue RNA - cerebellum [nTPM]":"7.2","Tissue RNA - cerebral cortex [nTPM]":"6.7","Tissue RNA - cervix [nTPM]":"6.8","Tissue RNA - choroid plexus [nTPM]":"22.2","Tissue RNA - colon [nTPM]":"11.0","Tissue RNA - duodenum [nTPM]":"10.3","Tissue RNA - endometrium 1 [nTPM]":"2.1","Tissue RNA - epididymis [nTPM]":"4.0","Tissue RNA - esophagus [nTPM]":"11.6","Tissue RNA - fallopian tube [nTPM]":"7.5","Tissue RNA - gallbladder [nTPM]":"8.5","Tissue RNA - heart muscle [nTPM]":"1.5","Tissue RNA - hippocampal formation [nTPM]":"5.9","Tissue RNA - hypothalamus [nTPM]":"5.4","Tissue RNA - kidney [nTPM]":"11.0","Tissue RNA - liver [nTPM]":"18.8","Tissue RNA - lung [nTPM]":"15.1","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"9.3","Tissue RNA - midbrain [nTPM]":"7.7","Tissue RNA - ovary [nTPM]":"2.3","Tissue RNA - pancreas [nTPM]":"20.2","Tissue RNA - parathyroid gland [nTPM]":"8.3","Tissue RNA - pituitary gland [nTPM]":"3.4","Tissue RNA - placenta [nTPM]":"3.9","Tissue RNA - pons [nTPM]":"8.3","Tissue RNA - prostate [nTPM]":"3.5","Tissue RNA - rectum [nTPM]":"11.2","Tissue RNA - retina [nTPM]":"2.3","Tissue RNA - salivary gland [nTPM]":"6.7","Tissue RNA - seminal vesicle [nTPM]":"4.6","Tissue RNA - skeletal muscle [nTPM]":"0.6","Tissue RNA - skin 1 [nTPM]":"11.3","Tissue RNA - small intestine [nTPM]":"10.0","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"5.4","Tissue RNA - spleen [nTPM]":"2.1","Tissue RNA - stomach 1 [nTPM]":"15.2","Tissue RNA - testis [nTPM]":"2.4","Tissue RNA - thalamus [nTPM]":"6.5","Tissue RNA - thymus [nTPM]":"0.9","Tissue RNA - thyroid gland [nTPM]":"31.4","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"2.8","Tissue RNA - urinary bladder [nTPM]":"5.0","Tissue RNA - vagina [nTPM]":"7.9","Tissue RNA - white matter [nTPM]":"7.4","Cell RNA - A-431 [nTPM]":"23.3","Cell RNA - A549 [nTPM]":"4.5","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"0.9","Cell RNA - ASC diff [nTPM]":"0.6","Cell RNA - ASC TERT1 [nTPM]":"0.9","Cell RNA - BEWO [nTPM]":"15.1","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"1.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.3","Cell RNA - CACO-2 [nTPM]":"20.7","Cell RNA - CAPAN-2 [nTPM]":"39.8","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"5.9","Cell RNA - fHDF\/TERT166 [nTPM]":"1.1","Cell RNA - GAMG [nTPM]":"8.3","Cell RNA - HaCaT [nTPM]":"33.4","Cell RNA - HAP1 [nTPM]":"7.2","Cell RNA - HBEC3-KT [nTPM]":"4.3","Cell RNA - HBF TERT88 [nTPM]":"7.8","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"12.2","Cell RNA - HEL [nTPM]":"2.4","Cell RNA - HeLa [nTPM]":"1.1","Cell RNA - Hep G2 [nTPM]":"9.8","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"1.2","Cell RNA - HMC-1 [nTPM]":"2.5","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"6.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.1","Cell RNA - hTERT-HME1 [nTPM]":"1.0","Cell RNA - hTERT-RPE1 [nTPM]":"1.6","Cell RNA - HUVEC TERT2 [nTPM]":"1.4","Cell RNA - JURKAT [nTPM]":"3.1","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"22.4","Cell RNA - MOLT-4 [nTPM]":"1.5","Cell RNA - NB-4 [nTPM]":"1.2","Cell RNA - NTERA-2 [nTPM]":"3.1","Cell RNA - OE19 [nTPM]":"8.0","Cell RNA - PC-3 [nTPM]":"2.1","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"6.0","Cell RNA - RPMI-8226 [nTPM]":"1.1","Cell RNA - RPTEC TERT1 [nTPM]":"25.7","Cell RNA - RT4 [nTPM]":"22.2","Cell RNA - SCLC-21H [nTPM]":"2.7","Cell RNA - SH-SY5Y [nTPM]":"2.8","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"27.2","Cell RNA - SK-MEL-30 [nTPM]":"0.9","Cell RNA - SuSa [nTPM]":"5.0","Cell RNA - T-47d [nTPM]":"14.7","Cell RNA - THP-1 [nTPM]":"4.0","Cell RNA - TIME [nTPM]":"1.2","Cell RNA - U-138 MG [nTPM]":"0.4","Cell RNA - U-2 OS [nTPM]":"7.7","Cell RNA - U-2197 [nTPM]":"1.8","Cell RNA - U-251 MG [nTPM]":"2.7","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"0.6","Blood RNA - basophil [nTPM]":"1.0","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"2.7","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"6.2","Brain RNA - basal ganglia [nTPM]":"6.5","Brain RNA - cerebellum [nTPM]":"7.2","Brain RNA - cerebral cortex [nTPM]":"6.7","Brain RNA - hippocampal formation [nTPM]":"5.9","Brain RNA - hypothalamus [nTPM]":"5.4","Brain RNA - medulla oblongata [nTPM]":"9.3","Brain RNA - midbrain [nTPM]":"7.7","Brain RNA - pons [nTPM]":"8.3","Brain RNA - spinal cord [nTPM]":"5.4","Brain RNA - thalamus [nTPM]":"6.5","Brain RNA - white matter [nTPM]":"7.4","Single Cell Type RNA - Adipocytes [nTPM]":"4.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"109.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"67.3","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"3.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"60.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"5.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"49.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"64.3","Single Cell Type RNA - Club cells [nTPM]":"51.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"30.3","Single Cell Type RNA - dendritic cells [nTPM]":"3.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"94.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"65.6","Single Cell Type RNA - Early spermatids [nTPM]":"1.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"78.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.1","Single Cell Type RNA - Endothelial cells [nTPM]":"10.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"26.3","Single Cell Type RNA - Erythroid cells [nTPM]":"2.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"61.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.5","Single Cell Type RNA - Fibroblasts [nTPM]":"5.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"46.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"119.7","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"6.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.2","Single Cell Type RNA - Hepatocytes [nTPM]":"48.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.0","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"45.1","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"12.9","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"2.4","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"3.9","Single Cell Type RNA - Muller glia cells [nTPM]":"2.8","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"64.6","Single Cell Type RNA - Paneth cells [nTPM]":"61.8","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"1.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"101.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"42.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"63.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.3","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.4","Single Cell Type RNA - Spermatocytes [nTPM]":"4.7","Single Cell Type RNA - Spermatogonia [nTPM]":"8.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"29.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.4","Single Cell Type RNA - T-cells [nTPM]":"4.3","Single Cell Type RNA - Theca cells [nTPM]":"0.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"47.9","Single Cell Type RNA - Urothelial cells [nTPM]":"224.0"},{"Gene":"OCRL","Gene synonym":["Dent-2","OCRL1"],"Ensembl":"ENSG00000122126","Gene description":"OCRL inositol polyphosphate-5-phosphatase","Uniprot":["Q01968"],"Chromosome":"X","Position":"129539849-129592561","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":["Hydrolase"],"Disease involvement":["Cataract","Ciliopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"3.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"dendritic cells":"1.2","monocytes":"3.6"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012495"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules","Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":["Microtubules","Centriolar satellite"],"Antibody RRID":{"HPA012495":"AB_1851804"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.93e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Tissue RNA - adipose tissue [nTPM]":"13.9","Tissue RNA - adrenal gland [nTPM]":"23.8","Tissue RNA - amygdala [nTPM]":"12.4","Tissue RNA - appendix [nTPM]":"4.7","Tissue RNA - basal ganglia [nTPM]":"13.2","Tissue RNA - bone marrow [nTPM]":"5.0","Tissue RNA - breast [nTPM]":"12.7","Tissue RNA - cerebellum [nTPM]":"5.3","Tissue RNA - cerebral cortex [nTPM]":"13.6","Tissue RNA - cervix [nTPM]":"14.9","Tissue RNA - choroid plexus [nTPM]":"27.2","Tissue RNA - colon [nTPM]":"16.4","Tissue RNA - duodenum [nTPM]":"8.0","Tissue RNA - endometrium 1 [nTPM]":"19.4","Tissue RNA - epididymis [nTPM]":"16.1","Tissue RNA - esophagus [nTPM]":"11.6","Tissue RNA - fallopian tube [nTPM]":"16.7","Tissue RNA - gallbladder [nTPM]":"8.3","Tissue RNA - heart muscle [nTPM]":"10.7","Tissue RNA - hippocampal formation [nTPM]":"13.1","Tissue RNA - hypothalamus [nTPM]":"20.3","Tissue RNA - kidney [nTPM]":"9.5","Tissue RNA - liver [nTPM]":"15.7","Tissue RNA - lung [nTPM]":"10.0","Tissue RNA - lymph node [nTPM]":"2.8","Tissue RNA - medulla oblongata [nTPM]":"9.6","Tissue RNA - midbrain [nTPM]":"14.0","Tissue RNA - ovary [nTPM]":"28.4","Tissue RNA - pancreas [nTPM]":"13.0","Tissue RNA - parathyroid gland [nTPM]":"34.6","Tissue RNA - pituitary gland [nTPM]":"25.6","Tissue RNA - placenta [nTPM]":"11.2","Tissue RNA - pons [nTPM]":"17.4","Tissue RNA - prostate [nTPM]":"18.5","Tissue RNA - rectum [nTPM]":"12.4","Tissue RNA - retina [nTPM]":"9.9","Tissue RNA - salivary gland [nTPM]":"11.0","Tissue RNA - seminal vesicle [nTPM]":"21.3","Tissue RNA - skeletal muscle [nTPM]":"14.8","Tissue RNA - skin 1 [nTPM]":"12.4","Tissue RNA - small intestine [nTPM]":"12.2","Tissue RNA - smooth muscle [nTPM]":"15.0","Tissue RNA - spinal cord [nTPM]":"7.6","Tissue RNA - spleen [nTPM]":"7.9","Tissue RNA - stomach 1 [nTPM]":"14.5","Tissue RNA - testis [nTPM]":"24.6","Tissue RNA - thalamus [nTPM]":"18.6","Tissue RNA - thymus [nTPM]":"4.4","Tissue RNA - thyroid gland [nTPM]":"16.8","Tissue RNA - tongue [nTPM]":"6.7","Tissue RNA - tonsil [nTPM]":"3.0","Tissue RNA - urinary bladder [nTPM]":"22.8","Tissue RNA - vagina [nTPM]":"12.3","Tissue RNA - white matter [nTPM]":"8.6","Cell RNA - A-431 [nTPM]":"19.3","Cell RNA - A549 [nTPM]":"20.5","Cell RNA - AF22 [nTPM]":"17.0","Cell RNA - AN3-CA [nTPM]":"18.7","Cell RNA - ASC diff [nTPM]":"29.3","Cell RNA - ASC TERT1 [nTPM]":"24.1","Cell RNA - BEWO [nTPM]":"17.1","Cell RNA - BJ [nTPM]":"28.5","Cell RNA - BJ hTERT+ [nTPM]":"22.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"28.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"26.3","Cell RNA - CACO-2 [nTPM]":"14.2","Cell RNA - CAPAN-2 [nTPM]":"13.3","Cell RNA - Daudi [nTPM]":"1.5","Cell RNA - EFO-21 [nTPM]":"46.7","Cell RNA - fHDF\/TERT166 [nTPM]":"24.1","Cell RNA - GAMG [nTPM]":"33.0","Cell RNA - HaCaT [nTPM]":"11.6","Cell RNA - HAP1 [nTPM]":"30.5","Cell RNA - HBEC3-KT [nTPM]":"20.9","Cell RNA - HBF TERT88 [nTPM]":"29.2","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"21.5","Cell RNA - HEL [nTPM]":"5.8","Cell RNA - HeLa [nTPM]":"18.5","Cell RNA - Hep G2 [nTPM]":"14.1","Cell RNA - HHSteC [nTPM]":"21.1","Cell RNA - HL-60 [nTPM]":"5.7","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"20.7","Cell RNA - hTCEpi [nTPM]":"27.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"28.3","Cell RNA - hTERT-HME1 [nTPM]":"27.3","Cell RNA - hTERT-RPE1 [nTPM]":"27.7","Cell RNA - HUVEC TERT2 [nTPM]":"21.2","Cell RNA - JURKAT [nTPM]":"8.4","Cell RNA - K-562 [nTPM]":"7.9","Cell RNA - Karpas-707 [nTPM]":"13.6","Cell RNA - LHCN-M2 [nTPM]":"28.7","Cell RNA - MCF7 [nTPM]":"24.2","Cell RNA - MOLT-4 [nTPM]":"4.3","Cell RNA - NB-4 [nTPM]":"8.2","Cell RNA - NTERA-2 [nTPM]":"6.2","Cell RNA - OE19 [nTPM]":"24.4","Cell RNA - PC-3 [nTPM]":"30.9","Cell RNA - REH [nTPM]":"4.2","Cell RNA - RH-30 [nTPM]":"17.6","Cell RNA - RPMI-8226 [nTPM]":"11.5","Cell RNA - RPTEC TERT1 [nTPM]":"16.1","Cell RNA - RT4 [nTPM]":"19.1","Cell RNA - SCLC-21H [nTPM]":"20.5","Cell RNA - SH-SY5Y [nTPM]":"26.1","Cell RNA - SiHa [nTPM]":"13.5","Cell RNA - SK-BR-3 [nTPM]":"18.0","Cell RNA - SK-MEL-30 [nTPM]":"14.6","Cell RNA - SuSa [nTPM]":"21.5","Cell RNA - T-47d [nTPM]":"13.2","Cell RNA - THP-1 [nTPM]":"10.0","Cell RNA - TIME [nTPM]":"19.3","Cell RNA - U-138 MG [nTPM]":"23.0","Cell RNA - U-2 OS [nTPM]":"10.6","Cell RNA - U-2197 [nTPM]":"24.6","Cell RNA - U-251 MG [nTPM]":"29.1","Cell RNA - U-266\/70 [nTPM]":"3.8","Cell RNA - U-266\/84 [nTPM]":"3.3","Cell RNA - U-698 [nTPM]":"3.7","Cell RNA - U-87 MG [nTPM]":"16.2","Cell RNA - U-937 [nTPM]":"21.4","Cell RNA - WM-115 [nTPM]":"18.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"1.2","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"3.6","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"12.4","Brain RNA - basal ganglia [nTPM]":"13.2","Brain RNA - cerebellum [nTPM]":"5.3","Brain RNA - cerebral cortex [nTPM]":"13.6","Brain RNA - hippocampal formation [nTPM]":"13.1","Brain RNA - hypothalamus [nTPM]":"20.3","Brain RNA - medulla oblongata [nTPM]":"9.6","Brain RNA - midbrain [nTPM]":"14.0","Brain RNA - pons [nTPM]":"17.4","Brain RNA - spinal cord [nTPM]":"7.6","Brain RNA - thalamus [nTPM]":"18.6","Brain RNA - white matter [nTPM]":"8.6","Single Cell Type RNA - Adipocytes [nTPM]":"6.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.8","Single Cell Type RNA - Astrocytes [nTPM]":"14.4","Single Cell Type RNA - B-cells [nTPM]":"2.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"9.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"8.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.3","Single Cell Type RNA - Early spermatids [nTPM]":"31.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.9","Single Cell Type RNA - Endothelial cells [nTPM]":"6.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.5","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"20.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.4","Single Cell Type RNA - Fibroblasts [nTPM]":"7.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"17.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.2","Single Cell Type RNA - Hepatocytes [nTPM]":"11.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.0","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"23.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.8","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"11.8","Single Cell Type RNA - Langerhans cells [nTPM]":"4.0","Single Cell Type RNA - Late spermatids [nTPM]":"8.9","Single Cell Type RNA - Leydig cells [nTPM]":"23.0","Single Cell Type RNA - Macrophages [nTPM]":"5.8","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"4.3","Single Cell Type RNA - Muller glia cells [nTPM]":"9.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.5","Single Cell Type RNA - Paneth cells [nTPM]":"8.3","Single Cell Type RNA - Peritubular cells [nTPM]":"34.3","Single Cell Type RNA - Plasma cells [nTPM]":"1.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.0","Single Cell Type RNA - Spermatocytes [nTPM]":"6.8","Single Cell Type RNA - Spermatogonia [nTPM]":"14.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.7","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"7.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.2","Single Cell Type RNA - Urothelial cells [nTPM]":"8.4"},{"Gene":"OGG1","Gene synonym":["HMMH","HOGG1","MUTM","OGH1"],"Ensembl":"ENSG00000114026","Gene description":"8-oxoguanine DNA glycosylase","Uniprot":["O15527"],"Chromosome":"3","Position":"9749944-9788219","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["Glycosidase","Hydrolase","Lyase","Multifunctional enzyme"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal tubular cells":"86.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027514","CAB047301"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB047301":null,"HPA027514":"AB_10602189"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.77e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.66e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.65e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Tissue RNA - adipose tissue [nTPM]":"12.6","Tissue RNA - adrenal gland [nTPM]":"13.8","Tissue RNA - amygdala [nTPM]":"18.6","Tissue RNA - appendix [nTPM]":"13.2","Tissue RNA - basal ganglia [nTPM]":"18.3","Tissue RNA - bone marrow [nTPM]":"12.2","Tissue RNA - breast [nTPM]":"12.8","Tissue RNA - cerebellum [nTPM]":"20.5","Tissue RNA - cerebral cortex [nTPM]":"19.6","Tissue RNA - cervix [nTPM]":"18.2","Tissue RNA - choroid plexus [nTPM]":"12.5","Tissue RNA - colon [nTPM]":"14.8","Tissue RNA - duodenum [nTPM]":"18.9","Tissue RNA - endometrium 1 [nTPM]":"17.1","Tissue RNA - epididymis [nTPM]":"10.3","Tissue RNA - esophagus [nTPM]":"9.6","Tissue RNA - fallopian tube [nTPM]":"16.9","Tissue RNA - gallbladder [nTPM]":"8.4","Tissue RNA - heart muscle [nTPM]":"11.8","Tissue RNA - hippocampal formation [nTPM]":"19.6","Tissue RNA - hypothalamus [nTPM]":"15.8","Tissue RNA - kidney [nTPM]":"30.3","Tissue RNA - liver [nTPM]":"20.7","Tissue RNA - lung [nTPM]":"10.7","Tissue RNA - lymph node [nTPM]":"26.2","Tissue RNA - medulla oblongata [nTPM]":"18.8","Tissue RNA - midbrain [nTPM]":"16.7","Tissue RNA - ovary [nTPM]":"22.5","Tissue RNA - pancreas [nTPM]":"10.6","Tissue RNA - parathyroid gland [nTPM]":"6.6","Tissue RNA - pituitary gland [nTPM]":"10.8","Tissue RNA - placenta [nTPM]":"8.6","Tissue RNA - pons [nTPM]":"17.9","Tissue RNA - prostate [nTPM]":"15.7","Tissue RNA - rectum [nTPM]":"8.1","Tissue RNA - retina [nTPM]":"12.1","Tissue RNA - salivary gland [nTPM]":"12.2","Tissue RNA - seminal vesicle [nTPM]":"10.1","Tissue RNA - skeletal muscle [nTPM]":"7.2","Tissue RNA - skin 1 [nTPM]":"9.6","Tissue RNA - small intestine [nTPM]":"17.2","Tissue RNA - smooth muscle [nTPM]":"9.8","Tissue RNA - spinal cord [nTPM]":"16.2","Tissue RNA - spleen [nTPM]":"15.2","Tissue RNA - stomach 1 [nTPM]":"12.4","Tissue RNA - testis [nTPM]":"8.6","Tissue RNA - thalamus [nTPM]":"17.5","Tissue RNA - thymus [nTPM]":"13.5","Tissue RNA - thyroid gland [nTPM]":"13.1","Tissue RNA - tongue [nTPM]":"8.0","Tissue RNA - tonsil [nTPM]":"21.2","Tissue RNA - urinary bladder [nTPM]":"15.3","Tissue RNA - vagina [nTPM]":"14.3","Tissue RNA - white matter [nTPM]":"17.4","Cell RNA - A-431 [nTPM]":"11.3","Cell RNA - A549 [nTPM]":"20.7","Cell RNA - AF22 [nTPM]":"20.3","Cell RNA - AN3-CA [nTPM]":"13.1","Cell RNA - ASC diff [nTPM]":"19.9","Cell RNA - ASC TERT1 [nTPM]":"22.3","Cell RNA - BEWO [nTPM]":"38.4","Cell RNA - BJ [nTPM]":"14.5","Cell RNA - BJ hTERT+ [nTPM]":"14.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"25.6","Cell RNA - CACO-2 [nTPM]":"19.9","Cell RNA - CAPAN-2 [nTPM]":"10.8","Cell RNA - Daudi [nTPM]":"68.5","Cell RNA - EFO-21 [nTPM]":"9.5","Cell RNA - fHDF\/TERT166 [nTPM]":"18.3","Cell RNA - GAMG [nTPM]":"34.1","Cell RNA - HaCaT [nTPM]":"10.8","Cell RNA - HAP1 [nTPM]":"12.1","Cell RNA - HBEC3-KT [nTPM]":"15.9","Cell RNA - HBF TERT88 [nTPM]":"9.0","Cell RNA - HDLM-2 [nTPM]":"25.1","Cell RNA - HEK 293 [nTPM]":"17.6","Cell RNA - HEL [nTPM]":"33.9","Cell RNA - HeLa [nTPM]":"32.5","Cell RNA - Hep G2 [nTPM]":"29.3","Cell RNA - HHSteC [nTPM]":"20.7","Cell RNA - HL-60 [nTPM]":"13.3","Cell RNA - HMC-1 [nTPM]":"20.9","Cell RNA - HSkMC [nTPM]":"22.3","Cell RNA - hTCEpi [nTPM]":"20.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"37.4","Cell RNA - hTERT-HME1 [nTPM]":"16.0","Cell RNA - hTERT-RPE1 [nTPM]":"17.4","Cell RNA - HUVEC TERT2 [nTPM]":"27.3","Cell RNA - JURKAT [nTPM]":"9.6","Cell RNA - K-562 [nTPM]":"11.0","Cell RNA - Karpas-707 [nTPM]":"10.9","Cell RNA - LHCN-M2 [nTPM]":"20.9","Cell RNA - MCF7 [nTPM]":"21.3","Cell RNA - MOLT-4 [nTPM]":"10.7","Cell RNA - NB-4 [nTPM]":"13.2","Cell RNA - NTERA-2 [nTPM]":"11.0","Cell RNA - OE19 [nTPM]":"10.3","Cell RNA - PC-3 [nTPM]":"29.3","Cell RNA - REH [nTPM]":"7.8","Cell RNA - RH-30 [nTPM]":"13.7","Cell RNA - RPMI-8226 [nTPM]":"22.4","Cell RNA - RPTEC TERT1 [nTPM]":"12.4","Cell RNA - RT4 [nTPM]":"5.7","Cell RNA - SCLC-21H [nTPM]":"9.0","Cell RNA - SH-SY5Y [nTPM]":"15.9","Cell RNA - SiHa [nTPM]":"18.4","Cell RNA - SK-BR-3 [nTPM]":"15.2","Cell RNA - SK-MEL-30 [nTPM]":"11.5","Cell RNA - SuSa [nTPM]":"10.4","Cell RNA - T-47d [nTPM]":"23.7","Cell RNA - THP-1 [nTPM]":"22.9","Cell RNA - TIME [nTPM]":"17.5","Cell RNA - U-138 MG [nTPM]":"21.9","Cell RNA - U-2 OS [nTPM]":"22.7","Cell RNA - U-2197 [nTPM]":"17.2","Cell RNA - U-251 MG [nTPM]":"24.0","Cell RNA - U-266\/70 [nTPM]":"10.7","Cell RNA - U-266\/84 [nTPM]":"16.9","Cell RNA - U-698 [nTPM]":"35.9","Cell RNA - U-87 MG [nTPM]":"17.4","Cell RNA - U-937 [nTPM]":"37.9","Cell RNA - WM-115 [nTPM]":"13.7","Blood RNA - basophil [nTPM]":"15.1","Blood RNA - classical monocyte [nTPM]":"10.9","Blood RNA - eosinophil [nTPM]":"20.7","Blood RNA - gdT-cell [nTPM]":"18.7","Blood RNA - intermediate monocyte [nTPM]":"9.0","Blood RNA - MAIT T-cell [nTPM]":"18.4","Blood RNA - memory B-cell [nTPM]":"13.9","Blood RNA - memory CD4 T-cell [nTPM]":"15.8","Blood RNA - memory CD8 T-cell [nTPM]":"15.3","Blood RNA - myeloid DC [nTPM]":"9.8","Blood RNA - naive B-cell [nTPM]":"16.5","Blood RNA - naive CD4 T-cell [nTPM]":"12.1","Blood RNA - naive CD8 T-cell [nTPM]":"11.5","Blood RNA - neutrophil [nTPM]":"2.9","Blood RNA - NK-cell [nTPM]":"27.0","Blood RNA - non-classical monocyte [nTPM]":"7.3","Blood RNA - plasmacytoid DC [nTPM]":"15.9","Blood RNA - T-reg [nTPM]":"21.0","Blood RNA - total PBMC [nTPM]":"10.9","Brain RNA - amygdala [nTPM]":"18.6","Brain RNA - basal ganglia [nTPM]":"18.3","Brain RNA - cerebellum [nTPM]":"20.5","Brain RNA - cerebral cortex [nTPM]":"19.6","Brain RNA - hippocampal formation [nTPM]":"19.6","Brain RNA - hypothalamus [nTPM]":"15.8","Brain RNA - medulla oblongata [nTPM]":"18.8","Brain RNA - midbrain [nTPM]":"16.7","Brain RNA - pons [nTPM]":"17.9","Brain RNA - spinal cord [nTPM]":"16.2","Brain RNA - thalamus [nTPM]":"17.5","Brain RNA - white matter [nTPM]":"17.4","Single Cell Type RNA - Adipocytes [nTPM]":"9.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.4","Single Cell Type RNA - Astrocytes [nTPM]":"15.3","Single Cell Type RNA - B-cells [nTPM]":"16.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"20.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"4.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.4","Single Cell Type RNA - dendritic cells [nTPM]":"16.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"7.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.2","Single Cell Type RNA - Endothelial cells [nTPM]":"10.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.0","Single Cell Type RNA - Erythroid cells [nTPM]":"22.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.1","Single Cell Type RNA - Fibroblasts [nTPM]":"11.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.4","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"10.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.0","Single Cell Type RNA - Hepatocytes [nTPM]":"11.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.0","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.8","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"9.0","Single Cell Type RNA - Langerhans cells [nTPM]":"5.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.8","Single Cell Type RNA - Leydig cells [nTPM]":"14.3","Single Cell Type RNA - Macrophages [nTPM]":"9.3","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"15.8","Single Cell Type RNA - Muller glia cells [nTPM]":"11.3","Single Cell Type RNA - NK-cells [nTPM]":"27.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.8","Single Cell Type RNA - Paneth cells [nTPM]":"11.0","Single Cell Type RNA - Peritubular cells [nTPM]":"13.5","Single Cell Type RNA - Plasma cells [nTPM]":"10.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"47.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"86.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"34.7","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.3","Single Cell Type RNA - Spermatocytes [nTPM]":"10.2","Single Cell Type RNA - Spermatogonia [nTPM]":"21.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.0","Single Cell Type RNA - T-cells [nTPM]":"12.9","Single Cell Type RNA - Theca cells [nTPM]":"12.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.0","Single Cell Type RNA - Urothelial cells [nTPM]":"5.4"},{"Gene":"OGT","Gene synonym":["FLJ23071","HRNT1","MGC22921","O-GLCNAC","OGT1"],"Ensembl":"ENSG00000147162","Gene description":"O-linked N-acetylglucosamine (GlcNAc) transferase","Uniprot":["O15294"],"Chromosome":"X","Position":"71533104-71575892","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Biological rhythms","Host-virus interaction","Ubl conjugation pathway"],"Molecular function":["Chromatin regulator","Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030751","HPA030752","HPA030753","HPA030754","CAB034099"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 65: Plasmacytoid DCs - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB034099":"AB_2157067","HPA030751":"AB_10600217","HPA030752":"AB_10601445","HPA030753":"AB_2673594","HPA030754":"AB_2673595"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.33e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.97e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.56e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.36e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.85e-7"},"Tissue RNA - adipose tissue [nTPM]":"59.3","Tissue RNA - adrenal gland [nTPM]":"55.9","Tissue RNA - amygdala [nTPM]":"39.7","Tissue RNA - appendix [nTPM]":"38.3","Tissue RNA - basal ganglia [nTPM]":"42.4","Tissue RNA - bone marrow [nTPM]":"61.5","Tissue RNA - breast [nTPM]":"62.7","Tissue RNA - cerebellum [nTPM]":"43.3","Tissue RNA - cerebral cortex [nTPM]":"51.6","Tissue RNA - cervix [nTPM]":"72.7","Tissue RNA - choroid plexus [nTPM]":"40.1","Tissue RNA - colon [nTPM]":"62.5","Tissue RNA - duodenum [nTPM]":"30.6","Tissue RNA - endometrium 1 [nTPM]":"56.0","Tissue RNA - epididymis [nTPM]":"62.2","Tissue RNA - esophagus [nTPM]":"52.8","Tissue RNA - fallopian tube [nTPM]":"76.4","Tissue RNA - gallbladder [nTPM]":"26.4","Tissue RNA - heart muscle [nTPM]":"55.5","Tissue RNA - hippocampal formation [nTPM]":"43.9","Tissue RNA - hypothalamus [nTPM]":"35.5","Tissue RNA - kidney [nTPM]":"61.6","Tissue RNA - liver [nTPM]":"45.8","Tissue RNA - lung [nTPM]":"70.7","Tissue RNA - lymph node [nTPM]":"71.9","Tissue RNA - medulla oblongata [nTPM]":"36.1","Tissue RNA - midbrain [nTPM]":"35.8","Tissue RNA - ovary [nTPM]":"85.5","Tissue RNA - pancreas [nTPM]":"102.4","Tissue RNA - parathyroid gland [nTPM]":"24.3","Tissue RNA - pituitary gland [nTPM]":"46.9","Tissue RNA - placenta [nTPM]":"26.4","Tissue RNA - pons [nTPM]":"37.9","Tissue RNA - prostate [nTPM]":"75.4","Tissue RNA - rectum [nTPM]":"39.6","Tissue RNA - retina [nTPM]":"36.9","Tissue RNA - salivary gland [nTPM]":"64.1","Tissue RNA - seminal vesicle [nTPM]":"27.1","Tissue RNA - skeletal muscle [nTPM]":"62.8","Tissue RNA - skin 1 [nTPM]":"68.6","Tissue RNA - small intestine [nTPM]":"86.4","Tissue RNA - smooth muscle [nTPM]":"24.5","Tissue RNA - spinal cord [nTPM]":"36.1","Tissue RNA - spleen [nTPM]":"122.8","Tissue RNA - stomach 1 [nTPM]":"67.4","Tissue RNA - testis [nTPM]":"19.0","Tissue RNA - thalamus [nTPM]":"36.2","Tissue RNA - thymus [nTPM]":"57.2","Tissue RNA - thyroid gland [nTPM]":"70.7","Tissue RNA - tongue [nTPM]":"39.2","Tissue RNA - tonsil [nTPM]":"57.8","Tissue RNA - urinary bladder [nTPM]":"55.7","Tissue RNA - vagina [nTPM]":"67.4","Tissue RNA - white matter [nTPM]":"44.3","Cell RNA - A-431 [nTPM]":"40.5","Cell RNA - A549 [nTPM]":"37.0","Cell RNA - AF22 [nTPM]":"47.1","Cell RNA - AN3-CA [nTPM]":"41.5","Cell RNA - ASC diff [nTPM]":"49.6","Cell RNA - ASC TERT1 [nTPM]":"45.6","Cell RNA - BEWO [nTPM]":"31.6","Cell RNA - BJ [nTPM]":"30.3","Cell RNA - BJ hTERT+ [nTPM]":"54.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"32.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"49.1","Cell RNA - CACO-2 [nTPM]":"39.3","Cell RNA - CAPAN-2 [nTPM]":"45.4","Cell RNA - Daudi [nTPM]":"47.9","Cell RNA - EFO-21 [nTPM]":"20.7","Cell RNA - fHDF\/TERT166 [nTPM]":"37.3","Cell RNA - GAMG [nTPM]":"33.3","Cell RNA - HaCaT [nTPM]":"49.1","Cell RNA - HAP1 [nTPM]":"52.0","Cell RNA - HBEC3-KT [nTPM]":"29.5","Cell RNA - HBF TERT88 [nTPM]":"39.4","Cell RNA - HDLM-2 [nTPM]":"41.1","Cell RNA - HEK 293 [nTPM]":"53.4","Cell RNA - HEL [nTPM]":"30.4","Cell RNA - HeLa [nTPM]":"98.6","Cell RNA - Hep G2 [nTPM]":"28.5","Cell RNA - HHSteC [nTPM]":"37.6","Cell RNA - HL-60 [nTPM]":"62.9","Cell RNA - HMC-1 [nTPM]":"48.1","Cell RNA - HSkMC [nTPM]":"43.6","Cell RNA - hTCEpi [nTPM]":"59.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"35.1","Cell RNA - hTERT-HME1 [nTPM]":"65.7","Cell RNA - hTERT-RPE1 [nTPM]":"55.5","Cell RNA - HUVEC TERT2 [nTPM]":"30.5","Cell RNA - JURKAT [nTPM]":"100.7","Cell RNA - K-562 [nTPM]":"31.1","Cell RNA - Karpas-707 [nTPM]":"160.4","Cell RNA - LHCN-M2 [nTPM]":"31.1","Cell RNA - MCF7 [nTPM]":"34.3","Cell RNA - MOLT-4 [nTPM]":"48.9","Cell RNA - NB-4 [nTPM]":"75.2","Cell RNA - NTERA-2 [nTPM]":"31.6","Cell RNA - OE19 [nTPM]":"35.5","Cell RNA - PC-3 [nTPM]":"49.8","Cell RNA - REH [nTPM]":"47.8","Cell RNA - RH-30 [nTPM]":"52.7","Cell RNA - RPMI-8226 [nTPM]":"62.1","Cell RNA - RPTEC TERT1 [nTPM]":"50.0","Cell RNA - RT4 [nTPM]":"45.9","Cell RNA - SCLC-21H [nTPM]":"24.1","Cell RNA - SH-SY5Y [nTPM]":"21.2","Cell RNA - SiHa [nTPM]":"46.9","Cell RNA - SK-BR-3 [nTPM]":"30.9","Cell RNA - SK-MEL-30 [nTPM]":"30.2","Cell RNA - SuSa [nTPM]":"35.5","Cell RNA - T-47d [nTPM]":"22.8","Cell RNA - THP-1 [nTPM]":"42.4","Cell RNA - TIME [nTPM]":"35.5","Cell RNA - U-138 MG [nTPM]":"34.6","Cell RNA - U-2 OS [nTPM]":"27.9","Cell RNA - U-2197 [nTPM]":"36.6","Cell RNA - U-251 MG [nTPM]":"17.9","Cell RNA - U-266\/70 [nTPM]":"43.5","Cell RNA - U-266\/84 [nTPM]":"33.5","Cell RNA - U-698 [nTPM]":"56.5","Cell RNA - U-87 MG [nTPM]":"24.4","Cell RNA - U-937 [nTPM]":"65.0","Cell RNA - WM-115 [nTPM]":"21.6","Blood RNA - basophil [nTPM]":"2.8","Blood RNA - classical monocyte [nTPM]":"4.6","Blood RNA - eosinophil [nTPM]":"2.0","Blood RNA - gdT-cell [nTPM]":"7.5","Blood RNA - intermediate monocyte [nTPM]":"5.7","Blood RNA - MAIT T-cell [nTPM]":"6.8","Blood RNA - memory B-cell [nTPM]":"7.4","Blood RNA - memory CD4 T-cell [nTPM]":"6.3","Blood RNA - memory CD8 T-cell [nTPM]":"6.2","Blood RNA - myeloid DC [nTPM]":"6.1","Blood RNA - naive B-cell [nTPM]":"6.2","Blood RNA - naive CD4 T-cell [nTPM]":"7.2","Blood RNA - naive CD8 T-cell [nTPM]":"7.4","Blood RNA - neutrophil [nTPM]":"1.9","Blood RNA - NK-cell [nTPM]":"10.4","Blood RNA - non-classical monocyte [nTPM]":"5.7","Blood RNA - plasmacytoid DC [nTPM]":"6.2","Blood RNA - T-reg [nTPM]":"6.2","Blood RNA - total PBMC [nTPM]":"5.6","Brain RNA - amygdala [nTPM]":"39.7","Brain RNA - basal ganglia [nTPM]":"42.4","Brain RNA - cerebellum [nTPM]":"43.3","Brain RNA - cerebral cortex [nTPM]":"51.6","Brain RNA - hippocampal formation [nTPM]":"43.9","Brain RNA - hypothalamus [nTPM]":"35.5","Brain RNA - medulla oblongata [nTPM]":"36.1","Brain RNA - midbrain [nTPM]":"35.8","Brain RNA - pons [nTPM]":"37.9","Brain RNA - spinal cord [nTPM]":"36.1","Brain RNA - thalamus [nTPM]":"36.2","Brain RNA - white matter [nTPM]":"44.3","Single Cell Type RNA - Adipocytes [nTPM]":"31.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"85.2","Single Cell Type RNA - Astrocytes [nTPM]":"52.9","Single Cell Type RNA - B-cells [nTPM]":"67.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"88.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"37.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"23.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"58.6","Single Cell Type RNA - Bipolar cells [nTPM]":"26.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"49.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"34.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"42.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"31.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"49.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.8","Single Cell Type RNA - dendritic cells [nTPM]":"130.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"31.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"14.4","Single Cell Type RNA - Early spermatids [nTPM]":"2.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"32.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"49.8","Single Cell Type RNA - Endothelial cells [nTPM]":"39.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"34.9","Single Cell Type RNA - Erythroid cells [nTPM]":"51.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"110.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.5","Single Cell Type RNA - Fibroblasts [nTPM]":"47.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"54.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"53.3","Single Cell Type RNA - granulocytes [nTPM]":"27.8","Single Cell Type RNA - Granulosa cells [nTPM]":"26.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"45.7","Single Cell Type RNA - Hepatocytes [nTPM]":"27.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.1","Single Cell Type RNA - Horizontal cells [nTPM]":"40.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"94.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"37.3","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"60.9","Single Cell Type RNA - Langerhans cells [nTPM]":"69.7","Single Cell Type RNA - Late spermatids [nTPM]":"4.8","Single Cell Type RNA - Leydig cells [nTPM]":"53.4","Single Cell Type RNA - Macrophages [nTPM]":"45.8","Single Cell Type RNA - Melanocytes [nTPM]":"35.6","Single Cell Type RNA - Microglial cells [nTPM]":"71.2","Single Cell Type RNA - monocytes [nTPM]":"51.6","Single Cell Type RNA - Muller glia cells [nTPM]":"11.3","Single Cell Type RNA - NK-cells [nTPM]":"51.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"92.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"97.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.6","Single Cell Type RNA - Paneth cells [nTPM]":"34.9","Single Cell Type RNA - Peritubular cells [nTPM]":"29.7","Single Cell Type RNA - Plasma cells [nTPM]":"147.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"53.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"34.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.8","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"44.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"42.2","Single Cell Type RNA - Spermatocytes [nTPM]":"2.5","Single Cell Type RNA - Spermatogonia [nTPM]":"6.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"63.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"84.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.9","Single Cell Type RNA - T-cells [nTPM]":"82.1","Single Cell Type RNA - Theca cells [nTPM]":"62.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"34.0","Single Cell Type RNA - Urothelial cells [nTPM]":"50.8"},{"Gene":"OPA1","Gene synonym":["FLJ12460","KIAA0567","MGM1","NPG","NTG"],"Ensembl":"ENSG00000198836","Gene description":"OPA1 mitochondrial dynamin like GTPase","Uniprot":["O60313"],"Chromosome":"3","Position":"193593144-193697811","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Apoptosis","Sensory transduction","Vision"],"Molecular function":["Hydrolase"],"Disease involvement":["Cardiomyopathy","Deafness","Disease variant","Neurodegeneration","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"135.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036926","HPA036927"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"10000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA036926":"AB_10671247","HPA036927":"AB_2675388"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.61e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.44e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.84e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Tissue RNA - adipose tissue [nTPM]":"15.0","Tissue RNA - adrenal gland [nTPM]":"12.0","Tissue RNA - amygdala [nTPM]":"14.3","Tissue RNA - appendix [nTPM]":"7.6","Tissue RNA - basal ganglia [nTPM]":"17.4","Tissue RNA - bone marrow [nTPM]":"25.6","Tissue RNA - breast [nTPM]":"12.8","Tissue RNA - cerebellum [nTPM]":"15.2","Tissue RNA - cerebral cortex [nTPM]":"19.5","Tissue RNA - cervix [nTPM]":"10.4","Tissue RNA - choroid plexus [nTPM]":"9.4","Tissue RNA - colon [nTPM]":"18.9","Tissue RNA - duodenum [nTPM]":"16.8","Tissue RNA - endometrium 1 [nTPM]":"10.9","Tissue RNA - epididymis [nTPM]":"9.1","Tissue RNA - esophagus [nTPM]":"14.6","Tissue RNA - fallopian tube [nTPM]":"8.1","Tissue RNA - gallbladder [nTPM]":"10.2","Tissue RNA - heart muscle [nTPM]":"39.3","Tissue RNA - hippocampal formation [nTPM]":"18.6","Tissue RNA - hypothalamus [nTPM]":"17.4","Tissue RNA - kidney [nTPM]":"18.3","Tissue RNA - liver [nTPM]":"20.9","Tissue RNA - lung [nTPM]":"8.5","Tissue RNA - lymph node [nTPM]":"11.8","Tissue RNA - medulla oblongata [nTPM]":"16.4","Tissue RNA - midbrain [nTPM]":"15.4","Tissue RNA - ovary [nTPM]":"8.4","Tissue RNA - pancreas [nTPM]":"10.1","Tissue RNA - parathyroid gland [nTPM]":"23.1","Tissue RNA - pituitary gland [nTPM]":"3.8","Tissue RNA - placenta [nTPM]":"11.7","Tissue RNA - pons [nTPM]":"16.8","Tissue RNA - prostate [nTPM]":"12.3","Tissue RNA - rectum [nTPM]":"16.6","Tissue RNA - retina [nTPM]":"9.6","Tissue RNA - salivary gland [nTPM]":"11.7","Tissue RNA - seminal vesicle [nTPM]":"13.3","Tissue RNA - skeletal muscle [nTPM]":"24.2","Tissue RNA - skin 1 [nTPM]":"11.9","Tissue RNA - small intestine [nTPM]":"13.8","Tissue RNA - smooth muscle [nTPM]":"13.5","Tissue RNA - spinal cord [nTPM]":"12.4","Tissue RNA - spleen [nTPM]":"9.3","Tissue RNA - stomach 1 [nTPM]":"14.6","Tissue RNA - testis [nTPM]":"6.3","Tissue RNA - thalamus [nTPM]":"15.2","Tissue RNA - thymus [nTPM]":"12.7","Tissue RNA - thyroid gland [nTPM]":"13.9","Tissue RNA - tongue [nTPM]":"44.5","Tissue RNA - tonsil [nTPM]":"12.4","Tissue RNA - urinary bladder [nTPM]":"13.0","Tissue RNA - vagina [nTPM]":"5.1","Tissue RNA - white matter [nTPM]":"13.7","Cell RNA - A-431 [nTPM]":"58.9","Cell RNA - A549 [nTPM]":"18.8","Cell RNA - AF22 [nTPM]":"18.2","Cell RNA - AN3-CA [nTPM]":"20.2","Cell RNA - ASC diff [nTPM]":"15.8","Cell RNA - ASC TERT1 [nTPM]":"25.0","Cell RNA - BEWO [nTPM]":"19.3","Cell RNA - BJ [nTPM]":"27.5","Cell RNA - BJ hTERT+ [nTPM]":"26.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"30.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"29.0","Cell RNA - CACO-2 [nTPM]":"45.2","Cell RNA - CAPAN-2 [nTPM]":"19.3","Cell RNA - Daudi [nTPM]":"38.6","Cell RNA - EFO-21 [nTPM]":"58.1","Cell RNA - fHDF\/TERT166 [nTPM]":"27.0","Cell RNA - GAMG [nTPM]":"27.3","Cell RNA - HaCaT [nTPM]":"37.3","Cell RNA - HAP1 [nTPM]":"32.7","Cell RNA - HBEC3-KT [nTPM]":"31.7","Cell RNA - HBF TERT88 [nTPM]":"53.5","Cell RNA - HDLM-2 [nTPM]":"46.5","Cell RNA - HEK 293 [nTPM]":"25.7","Cell RNA - HEL [nTPM]":"67.9","Cell RNA - HeLa [nTPM]":"16.7","Cell RNA - Hep G2 [nTPM]":"23.1","Cell RNA - HHSteC [nTPM]":"24.9","Cell RNA - HL-60 [nTPM]":"55.8","Cell RNA - HMC-1 [nTPM]":"29.8","Cell RNA - HSkMC [nTPM]":"28.4","Cell RNA - hTCEpi [nTPM]":"27.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"30.0","Cell RNA - hTERT-HME1 [nTPM]":"40.9","Cell RNA - hTERT-RPE1 [nTPM]":"18.5","Cell RNA - HUVEC TERT2 [nTPM]":"26.2","Cell RNA - JURKAT [nTPM]":"15.7","Cell RNA - K-562 [nTPM]":"28.4","Cell RNA - Karpas-707 [nTPM]":"37.0","Cell RNA - LHCN-M2 [nTPM]":"30.2","Cell RNA - MCF7 [nTPM]":"46.5","Cell RNA - MOLT-4 [nTPM]":"21.9","Cell RNA - NB-4 [nTPM]":"30.9","Cell RNA - NTERA-2 [nTPM]":"25.8","Cell RNA - OE19 [nTPM]":"33.9","Cell RNA - PC-3 [nTPM]":"59.9","Cell RNA - REH [nTPM]":"27.8","Cell RNA - RH-30 [nTPM]":"40.1","Cell RNA - RPMI-8226 [nTPM]":"41.6","Cell RNA - RPTEC TERT1 [nTPM]":"22.7","Cell RNA - RT4 [nTPM]":"36.1","Cell RNA - SCLC-21H [nTPM]":"39.8","Cell RNA - SH-SY5Y [nTPM]":"24.2","Cell RNA - SiHa [nTPM]":"41.8","Cell RNA - SK-BR-3 [nTPM]":"46.3","Cell RNA - SK-MEL-30 [nTPM]":"29.5","Cell RNA - SuSa [nTPM]":"14.1","Cell RNA - T-47d [nTPM]":"60.3","Cell RNA - THP-1 [nTPM]":"43.5","Cell RNA - TIME [nTPM]":"26.3","Cell RNA - U-138 MG [nTPM]":"27.7","Cell RNA - U-2 OS [nTPM]":"20.8","Cell RNA - U-2197 [nTPM]":"29.3","Cell RNA - U-251 MG [nTPM]":"58.7","Cell RNA - U-266\/70 [nTPM]":"33.1","Cell RNA - U-266\/84 [nTPM]":"41.3","Cell RNA - U-698 [nTPM]":"74.0","Cell RNA - U-87 MG [nTPM]":"30.5","Cell RNA - U-937 [nTPM]":"43.7","Cell RNA - WM-115 [nTPM]":"28.4","Blood RNA - basophil [nTPM]":"9.7","Blood RNA - classical monocyte [nTPM]":"7.3","Blood RNA - eosinophil [nTPM]":"7.1","Blood RNA - gdT-cell [nTPM]":"5.8","Blood RNA - intermediate monocyte [nTPM]":"8.2","Blood RNA - MAIT T-cell [nTPM]":"5.5","Blood RNA - memory B-cell [nTPM]":"6.8","Blood RNA - memory CD4 T-cell [nTPM]":"5.5","Blood RNA - memory CD8 T-cell [nTPM]":"5.6","Blood RNA - myeloid DC [nTPM]":"7.8","Blood RNA - naive B-cell [nTPM]":"5.1","Blood RNA - naive CD4 T-cell [nTPM]":"5.6","Blood RNA - naive CD8 T-cell [nTPM]":"6.0","Blood RNA - neutrophil [nTPM]":"2.7","Blood RNA - NK-cell [nTPM]":"4.7","Blood RNA - non-classical monocyte [nTPM]":"17.3","Blood RNA - plasmacytoid DC [nTPM]":"4.0","Blood RNA - T-reg [nTPM]":"6.6","Blood RNA - total PBMC [nTPM]":"5.2","Brain RNA - amygdala [nTPM]":"14.3","Brain RNA - basal ganglia [nTPM]":"17.4","Brain RNA - cerebellum [nTPM]":"15.2","Brain RNA - cerebral cortex [nTPM]":"19.5","Brain RNA - hippocampal formation [nTPM]":"18.6","Brain RNA - hypothalamus [nTPM]":"17.4","Brain RNA - medulla oblongata [nTPM]":"16.4","Brain RNA - midbrain [nTPM]":"15.4","Brain RNA - pons [nTPM]":"16.8","Brain RNA - spinal cord [nTPM]":"12.4","Brain RNA - thalamus [nTPM]":"15.2","Brain RNA - white matter [nTPM]":"13.7","Single Cell Type RNA - Adipocytes [nTPM]":"24.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"24.0","Single Cell Type RNA - Astrocytes [nTPM]":"72.1","Single Cell Type RNA - B-cells [nTPM]":"27.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"19.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"20.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"135.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"20.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.0","Single Cell Type RNA - dendritic cells [nTPM]":"24.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"31.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"19.3","Single Cell Type RNA - Early spermatids [nTPM]":"7.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"25.2","Single Cell Type RNA - Endothelial cells [nTPM]":"23.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"23.4","Single Cell Type RNA - Erythroid cells [nTPM]":"86.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"106.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"24.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.9","Single Cell Type RNA - Fibroblasts [nTPM]":"24.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"31.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.1","Single Cell Type RNA - granulocytes [nTPM]":"19.6","Single Cell Type RNA - Granulosa cells [nTPM]":"25.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.3","Single Cell Type RNA - Hepatocytes [nTPM]":"39.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.9","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"106.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.6","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"25.6","Single Cell Type RNA - Langerhans cells [nTPM]":"14.7","Single Cell Type RNA - Late spermatids [nTPM]":"13.5","Single Cell Type RNA - Leydig cells [nTPM]":"15.8","Single Cell Type RNA - Macrophages [nTPM]":"28.1","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"58.1","Single Cell Type RNA - monocytes [nTPM]":"22.9","Single Cell Type RNA - Muller glia cells [nTPM]":"14.6","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"87.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"98.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"28.9","Single Cell Type RNA - Paneth cells [nTPM]":"12.1","Single Cell Type RNA - Peritubular cells [nTPM]":"14.7","Single Cell Type RNA - Plasma cells [nTPM]":"29.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"34.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.2","Single Cell Type RNA - Spermatocytes [nTPM]":"15.1","Single Cell Type RNA - Spermatogonia [nTPM]":"16.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"34.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.9","Single Cell Type RNA - T-cells [nTPM]":"22.3","Single Cell Type RNA - Theca cells [nTPM]":"28.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.7","Single Cell Type RNA - Urothelial cells [nTPM]":"22.1"},{"Gene":"OPLAH","Gene synonym":["5-Opase","OPLA"],"Ensembl":"ENSG00000178814","Gene description":"5-oxoprolinase, ATP-hydrolysing","Uniprot":["O14841"],"Chromosome":"8","Position":"144051266-144063965","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"66.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"115.7","Late spermatids":"231.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"1.1","neutrophil":"1.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"1.1","monocytes":"1.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AN3-CA":"33.9","BEWO":"21.0","Hep G2":"18.8","PC-3":"26.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026562","HPA028260","HPA052429"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"34000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 23: AN3-CA - Transcription regulation","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":null,"Antibody RRID":{"HPA026562":"AB_1854804","HPA028260":"AB_10601383","HPA052429":"AB_2681830"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.53e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.24e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.2","Tissue RNA - adrenal gland [nTPM]":"14.8","Tissue RNA - amygdala [nTPM]":"3.3","Tissue RNA - appendix [nTPM]":"1.9","Tissue RNA - basal ganglia [nTPM]":"5.6","Tissue RNA - bone marrow [nTPM]":"2.7","Tissue RNA - breast [nTPM]":"8.6","Tissue RNA - cerebellum [nTPM]":"8.1","Tissue RNA - cerebral cortex [nTPM]":"3.7","Tissue RNA - cervix [nTPM]":"6.4","Tissue RNA - choroid plexus [nTPM]":"5.7","Tissue RNA - colon [nTPM]":"15.0","Tissue RNA - duodenum [nTPM]":"13.8","Tissue RNA - endometrium 1 [nTPM]":"4.8","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"15.6","Tissue RNA - fallopian tube [nTPM]":"4.2","Tissue RNA - gallbladder [nTPM]":"2.5","Tissue RNA - heart muscle [nTPM]":"35.1","Tissue RNA - hippocampal formation [nTPM]":"2.9","Tissue RNA - hypothalamus [nTPM]":"2.7","Tissue RNA - kidney [nTPM]":"15.8","Tissue RNA - liver [nTPM]":"34.3","Tissue RNA - lung [nTPM]":"6.4","Tissue RNA - lymph node [nTPM]":"0.8","Tissue RNA - medulla oblongata [nTPM]":"12.2","Tissue RNA - midbrain [nTPM]":"5.6","Tissue RNA - ovary [nTPM]":"5.7","Tissue RNA - pancreas [nTPM]":"10.0","Tissue RNA - parathyroid gland [nTPM]":"6.7","Tissue RNA - pituitary gland [nTPM]":"3.2","Tissue RNA - placenta [nTPM]":"1.3","Tissue RNA - pons [nTPM]":"12.5","Tissue RNA - prostate [nTPM]":"8.9","Tissue RNA - rectum [nTPM]":"2.2","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"11.2","Tissue RNA - seminal vesicle [nTPM]":"5.7","Tissue RNA - skeletal muscle [nTPM]":"34.2","Tissue RNA - skin 1 [nTPM]":"13.3","Tissue RNA - small intestine [nTPM]":"12.2","Tissue RNA - smooth muscle [nTPM]":"1.1","Tissue RNA - spinal cord [nTPM]":"3.9","Tissue RNA - spleen [nTPM]":"9.1","Tissue RNA - stomach 1 [nTPM]":"19.7","Tissue RNA - testis [nTPM]":"66.5","Tissue RNA - thalamus [nTPM]":"5.3","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"5.9","Tissue RNA - tongue [nTPM]":"15.4","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"4.8","Tissue RNA - vagina [nTPM]":"9.5","Tissue RNA - white matter [nTPM]":"6.5","Cell RNA - A-431 [nTPM]":"4.2","Cell RNA - A549 [nTPM]":"4.2","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"33.9","Cell RNA - ASC diff [nTPM]":"1.5","Cell RNA - ASC TERT1 [nTPM]":"3.1","Cell RNA - BEWO [nTPM]":"21.0","Cell RNA - BJ [nTPM]":"2.1","Cell RNA - BJ hTERT+ [nTPM]":"1.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.7","Cell RNA - CACO-2 [nTPM]":"8.1","Cell RNA - CAPAN-2 [nTPM]":"7.8","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"6.8","Cell RNA - fHDF\/TERT166 [nTPM]":"3.8","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"5.5","Cell RNA - HAP1 [nTPM]":"1.0","Cell RNA - HBEC3-KT [nTPM]":"3.1","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"1.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"1.4","Cell RNA - HeLa [nTPM]":"7.0","Cell RNA - Hep G2 [nTPM]":"18.8","Cell RNA - HHSteC [nTPM]":"10.5","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"4.4","Cell RNA - hTCEpi [nTPM]":"13.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.4","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"5.8","Cell RNA - K-562 [nTPM]":"5.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"4.8","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"3.3","Cell RNA - NTERA-2 [nTPM]":"2.8","Cell RNA - OE19 [nTPM]":"6.5","Cell RNA - PC-3 [nTPM]":"26.2","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"5.6","Cell RNA - RPTEC TERT1 [nTPM]":"3.6","Cell RNA - RT4 [nTPM]":"5.1","Cell RNA - SCLC-21H [nTPM]":"1.2","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"1.4","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"8.8","Cell RNA - THP-1 [nTPM]":"4.6","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"5.5","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"1.4","Cell RNA - U-266\/70 [nTPM]":"1.1","Cell RNA - U-266\/84 [nTPM]":"1.5","Cell RNA - U-698 [nTPM]":"1.1","Cell RNA - U-87 MG [nTPM]":"0.5","Cell RNA - U-937 [nTPM]":"1.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"3.3","Brain RNA - basal ganglia [nTPM]":"5.6","Brain RNA - cerebellum [nTPM]":"8.1","Brain RNA - cerebral cortex [nTPM]":"3.7","Brain RNA - hippocampal formation [nTPM]":"2.9","Brain RNA - hypothalamus [nTPM]":"2.7","Brain RNA - medulla oblongata [nTPM]":"12.2","Brain RNA - midbrain [nTPM]":"5.6","Brain RNA - pons [nTPM]":"12.5","Brain RNA - spinal cord [nTPM]":"3.9","Brain RNA - thalamus [nTPM]":"5.3","Brain RNA - white matter [nTPM]":"6.5","Single Cell Type RNA - Adipocytes [nTPM]":"1.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.2","Single Cell Type RNA - Astrocytes [nTPM]":"9.1","Single Cell Type RNA - B-cells [nTPM]":"0.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"1.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"4.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.7","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"37.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"3.8","Single Cell Type RNA - Early spermatids [nTPM]":"115.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.7","Single Cell Type RNA - Endothelial cells [nTPM]":"1.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.7","Single Cell Type RNA - Fibroblasts [nTPM]":"2.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"6.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"25.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"6.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.5","Single Cell Type RNA - Late spermatids [nTPM]":"231.7","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"3.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"2.1","Single Cell Type RNA - Muller glia cells [nTPM]":"4.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.6","Single Cell Type RNA - Paneth cells [nTPM]":"13.1","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"0.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.2","Single Cell Type RNA - Spermatocytes [nTPM]":"3.1","Single Cell Type RNA - Spermatogonia [nTPM]":"2.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"10.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.2","Single Cell Type RNA - Urothelial cells [nTPM]":"3.0"},{"Gene":"OPN1LW","Gene synonym":["CBBM","CBP","COD5","RCP"],"Ensembl":"ENSG00000102076","Gene description":"Opsin 1, long wave sensitive","Uniprot":["P04000"],"Chromosome":"X","Position":"154144243-154159032","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["G-protein coupled receptor","Photoreceptor protein","Receptor","Retinal protein","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"2568","RNA tissue specific nTPM":{"retina":"256.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"20","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"725.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"256.7","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"9.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"725.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"12.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"35.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"OPN1MW","Gene synonym":["CBBM","CBD","COD5","GCP","OPN1MW1"],"Ensembl":"ENSG00000268221","Gene description":"Opsin 1, medium wave sensitive","Uniprot":["P04001"],"Chromosome":"X","Position":"154182596-154196861","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["G-protein coupled receptor","Photoreceptor protein","Receptor","Retinal protein","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"133","RNA tissue specific nTPM":{"retina":"13.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"111","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"33.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"13.3","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"OPN1SW","Gene synonym":["BCP","BOP","CBT"],"Ensembl":"ENSG00000128617","Gene description":"Opsin 1, short wave sensitive","Uniprot":["P03999"],"Chromosome":"7","Position":"128772485-128775794","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["G-protein coupled receptor","Photoreceptor protein","Receptor","Retinal protein","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"84","RNA tissue specific nTPM":{"retina":"41.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"41.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"LHCN-M2":"1.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013562","HPA014083"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Cytokinetic bridge","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies","Cytokinetic bridge","Cytosol"],"Antibody RRID":{"HPA013562":"AB_2668850","HPA014083":"AB_2668938"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.50e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.26e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.98e-8"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.33e-4"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"41.0","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"1.5","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"OPTN","Gene synonym":["FIP-2","FIP2","GLC1E","HIP7","HYPL","NRP","TFIIIA-INTP"],"Ensembl":"ENSG00000123240","Gene description":"Optineurin","Uniprot":["Q96CV9"],"Chromosome":"10","Position":"13099449-13138308","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Autophagy","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":["Amyotrophic lateral sclerosis","Disease variant","Glaucoma","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"skeletal muscle":"879.4","tongue":"394.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"933.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003279","HPA003360","CAB019303"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"370000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB019303":null,"HPA003279":"AB_1079527","HPA003360":"AB_1079528"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.81e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Tissue RNA - adipose tissue [nTPM]":"92.7","Tissue RNA - adrenal gland [nTPM]":"90.4","Tissue RNA - amygdala [nTPM]":"45.7","Tissue RNA - appendix [nTPM]":"35.8","Tissue RNA - basal ganglia [nTPM]":"53.5","Tissue RNA - bone marrow [nTPM]":"50.1","Tissue RNA - breast [nTPM]":"64.0","Tissue RNA - cerebellum [nTPM]":"45.9","Tissue RNA - cerebral cortex [nTPM]":"55.9","Tissue RNA - cervix [nTPM]":"52.3","Tissue RNA - choroid plexus [nTPM]":"36.8","Tissue RNA - colon [nTPM]":"55.4","Tissue RNA - duodenum [nTPM]":"63.2","Tissue RNA - endometrium 1 [nTPM]":"39.7","Tissue RNA - epididymis [nTPM]":"21.9","Tissue RNA - esophagus [nTPM]":"61.8","Tissue RNA - fallopian tube [nTPM]":"37.7","Tissue RNA - gallbladder [nTPM]":"41.6","Tissue RNA - heart muscle [nTPM]":"105.7","Tissue RNA - hippocampal formation [nTPM]":"54.9","Tissue RNA - hypothalamus [nTPM]":"49.2","Tissue RNA - kidney [nTPM]":"72.3","Tissue RNA - liver [nTPM]":"73.8","Tissue RNA - lung [nTPM]":"58.9","Tissue RNA - lymph node [nTPM]":"45.7","Tissue RNA - medulla oblongata [nTPM]":"48.0","Tissue RNA - midbrain [nTPM]":"53.9","Tissue RNA - ovary [nTPM]":"92.1","Tissue RNA - pancreas [nTPM]":"35.4","Tissue RNA - parathyroid gland [nTPM]":"33.1","Tissue RNA - pituitary gland [nTPM]":"33.8","Tissue RNA - placenta [nTPM]":"57.5","Tissue RNA - pons [nTPM]":"52.9","Tissue RNA - prostate [nTPM]":"34.1","Tissue RNA - rectum [nTPM]":"57.2","Tissue RNA - retina [nTPM]":"48.8","Tissue RNA - salivary gland [nTPM]":"46.3","Tissue RNA - seminal vesicle [nTPM]":"41.4","Tissue RNA - skeletal muscle [nTPM]":"879.4","Tissue RNA - skin 1 [nTPM]":"77.9","Tissue RNA - small intestine [nTPM]":"69.6","Tissue RNA - smooth muscle [nTPM]":"43.4","Tissue RNA - spinal cord [nTPM]":"44.3","Tissue RNA - spleen [nTPM]":"57.3","Tissue RNA - stomach 1 [nTPM]":"56.1","Tissue RNA - testis [nTPM]":"72.8","Tissue RNA - thalamus [nTPM]":"45.4","Tissue RNA - thymus [nTPM]":"30.1","Tissue RNA - thyroid gland [nTPM]":"27.1","Tissue RNA - tongue [nTPM]":"394.5","Tissue RNA - tonsil [nTPM]":"37.6","Tissue RNA - urinary bladder [nTPM]":"43.8","Tissue RNA - vagina [nTPM]":"56.3","Tissue RNA - white matter [nTPM]":"49.0","Cell RNA - A-431 [nTPM]":"83.3","Cell RNA - A549 [nTPM]":"23.1","Cell RNA - AF22 [nTPM]":"12.8","Cell RNA - AN3-CA [nTPM]":"17.8","Cell RNA - ASC diff [nTPM]":"171.4","Cell RNA - ASC TERT1 [nTPM]":"175.6","Cell RNA - BEWO [nTPM]":"15.2","Cell RNA - BJ [nTPM]":"97.6","Cell RNA - BJ hTERT+ [nTPM]":"110.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"72.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"119.0","Cell RNA - CACO-2 [nTPM]":"41.1","Cell RNA - CAPAN-2 [nTPM]":"108.1","Cell RNA - Daudi [nTPM]":"0.7","Cell RNA - EFO-21 [nTPM]":"37.6","Cell RNA - fHDF\/TERT166 [nTPM]":"134.3","Cell RNA - GAMG [nTPM]":"113.2","Cell RNA - HaCaT [nTPM]":"75.6","Cell RNA - HAP1 [nTPM]":"17.3","Cell RNA - HBEC3-KT [nTPM]":"93.5","Cell RNA - HBF TERT88 [nTPM]":"54.8","Cell RNA - HDLM-2 [nTPM]":"192.9","Cell RNA - HEK 293 [nTPM]":"9.2","Cell RNA - HEL [nTPM]":"17.2","Cell RNA - HeLa [nTPM]":"32.1","Cell RNA - Hep G2 [nTPM]":"22.0","Cell RNA - HHSteC [nTPM]":"175.4","Cell RNA - HL-60 [nTPM]":"0.6","Cell RNA - HMC-1 [nTPM]":"59.5","Cell RNA - HSkMC [nTPM]":"94.6","Cell RNA - hTCEpi [nTPM]":"72.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"69.2","Cell RNA - hTERT-HME1 [nTPM]":"71.8","Cell RNA - hTERT-RPE1 [nTPM]":"177.9","Cell RNA - HUVEC TERT2 [nTPM]":"62.4","Cell RNA - JURKAT [nTPM]":"23.8","Cell RNA - K-562 [nTPM]":"21.5","Cell RNA - Karpas-707 [nTPM]":"123.7","Cell RNA - LHCN-M2 [nTPM]":"98.7","Cell RNA - MCF7 [nTPM]":"17.6","Cell RNA - MOLT-4 [nTPM]":"8.3","Cell RNA - NB-4 [nTPM]":"2.3","Cell RNA - NTERA-2 [nTPM]":"5.2","Cell RNA - OE19 [nTPM]":"22.4","Cell RNA - PC-3 [nTPM]":"10.3","Cell RNA - REH [nTPM]":"1.4","Cell RNA - RH-30 [nTPM]":"25.5","Cell RNA - RPMI-8226 [nTPM]":"8.5","Cell RNA - RPTEC TERT1 [nTPM]":"87.9","Cell RNA - RT4 [nTPM]":"57.6","Cell RNA - SCLC-21H [nTPM]":"2.8","Cell RNA - SH-SY5Y [nTPM]":"13.6","Cell RNA - SiHa [nTPM]":"84.9","Cell RNA - SK-BR-3 [nTPM]":"25.0","Cell RNA - SK-MEL-30 [nTPM]":"64.3","Cell RNA - SuSa [nTPM]":"49.9","Cell RNA - T-47d [nTPM]":"54.6","Cell RNA - THP-1 [nTPM]":"11.4","Cell RNA - TIME [nTPM]":"171.6","Cell RNA - U-138 MG [nTPM]":"58.8","Cell RNA - U-2 OS [nTPM]":"28.9","Cell RNA - U-2197 [nTPM]":"81.0","Cell RNA - U-251 MG [nTPM]":"27.5","Cell RNA - U-266\/70 [nTPM]":"63.3","Cell RNA - U-266\/84 [nTPM]":"23.5","Cell RNA - U-698 [nTPM]":"0.6","Cell RNA - U-87 MG [nTPM]":"88.3","Cell RNA - U-937 [nTPM]":"14.3","Cell RNA - WM-115 [nTPM]":"11.4","Blood RNA - basophil [nTPM]":"47.9","Blood RNA - classical monocyte [nTPM]":"2.5","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"56.1","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"43.3","Blood RNA - memory B-cell [nTPM]":"18.0","Blood RNA - memory CD4 T-cell [nTPM]":"71.2","Blood RNA - memory CD8 T-cell [nTPM]":"65.8","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"11.7","Blood RNA - naive CD4 T-cell [nTPM]":"28.0","Blood RNA - naive CD8 T-cell [nTPM]":"34.5","Blood RNA - neutrophil [nTPM]":"1.7","Blood RNA - NK-cell [nTPM]":"51.2","Blood RNA - non-classical monocyte [nTPM]":"3.8","Blood RNA - plasmacytoid DC [nTPM]":"5.2","Blood RNA - T-reg [nTPM]":"109.6","Blood RNA - total PBMC [nTPM]":"30.2","Brain RNA - amygdala [nTPM]":"45.7","Brain RNA - basal ganglia [nTPM]":"53.5","Brain RNA - cerebellum [nTPM]":"45.9","Brain RNA - cerebral cortex [nTPM]":"55.9","Brain RNA - hippocampal formation [nTPM]":"54.9","Brain RNA - hypothalamus [nTPM]":"49.2","Brain RNA - medulla oblongata [nTPM]":"48.0","Brain RNA - midbrain [nTPM]":"53.9","Brain RNA - pons [nTPM]":"52.9","Brain RNA - spinal cord [nTPM]":"44.3","Brain RNA - thalamus [nTPM]":"45.4","Brain RNA - white matter [nTPM]":"49.0","Single Cell Type RNA - Adipocytes [nTPM]":"68.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"67.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.4","Single Cell Type RNA - Astrocytes [nTPM]":"18.6","Single Cell Type RNA - B-cells [nTPM]":"25.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"74.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"46.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"104.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"67.2","Single Cell Type RNA - Bipolar cells [nTPM]":"38.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"30.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"32.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"237.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"68.6","Single Cell Type RNA - Club cells [nTPM]":"81.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"112.8","Single Cell Type RNA - dendritic cells [nTPM]":"89.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"199.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"135.5","Single Cell Type RNA - Early spermatids [nTPM]":"281.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"36.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"38.6","Single Cell Type RNA - Endothelial cells [nTPM]":"82.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"42.6","Single Cell Type RNA - Erythroid cells [nTPM]":"126.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"48.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"114.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"39.8","Single Cell Type RNA - Fibroblasts [nTPM]":"91.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"88.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"37.4","Single Cell Type RNA - granulocytes [nTPM]":"70.8","Single Cell Type RNA - Granulosa cells [nTPM]":"92.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"47.8","Single Cell Type RNA - Hepatocytes [nTPM]":"30.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"31.6","Single Cell Type RNA - Horizontal cells [nTPM]":"90.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"26.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"106.4","Single Cell Type RNA - Ionocytes [nTPM]":"65.1","Single Cell Type RNA - Kupffer cells [nTPM]":"15.1","Single Cell Type RNA - Langerhans cells [nTPM]":"26.0","Single Cell Type RNA - Late spermatids [nTPM]":"933.6","Single Cell Type RNA - Leydig cells [nTPM]":"95.7","Single Cell Type RNA - Macrophages [nTPM]":"14.5","Single Cell Type RNA - Melanocytes [nTPM]":"90.7","Single Cell Type RNA - Microglial cells [nTPM]":"25.3","Single Cell Type RNA - monocytes [nTPM]":"36.6","Single Cell Type RNA - Muller glia cells [nTPM]":"36.4","Single Cell Type RNA - NK-cells [nTPM]":"119.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"28.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"166.3","Single Cell Type RNA - Paneth cells [nTPM]":"186.9","Single Cell Type RNA - Peritubular cells [nTPM]":"103.4","Single Cell Type RNA - Plasma cells [nTPM]":"86.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"92.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"209.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"162.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"73.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"103.4","Single Cell Type RNA - Sertoli cells [nTPM]":"111.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"63.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"106.6","Single Cell Type RNA - Spermatocytes [nTPM]":"102.0","Single Cell Type RNA - Spermatogonia [nTPM]":"13.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"58.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"77.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"75.4","Single Cell Type RNA - T-cells [nTPM]":"107.5","Single Cell Type RNA - Theca cells [nTPM]":"166.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"44.1","Single Cell Type RNA - Urothelial cells [nTPM]":"75.0"},{"Gene":"ORAI1","Gene synonym":["CRACM1","FLJ14466","TMEM142A"],"Ensembl":"ENSG00000276045","Gene description":"ORAI calcium release-activated calcium modulator 1","Uniprot":["Q96D31"],"Chromosome":"12","Position":"121626550-121642677","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Adaptive immunity","Calcium transport","Immunity","Ion transport","Transport"],"Molecular function":["Calcium channel","Calmodulin-binding","Ion channel"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"60.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"92.3","NK-cells":"88.6","Theca cells":"86.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"NB-4":"81.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016583"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA016583":"AB_1848720"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.30e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.8","Tissue RNA - adrenal gland [nTPM]":"5.4","Tissue RNA - amygdala [nTPM]":"4.4","Tissue RNA - appendix [nTPM]":"9.6","Tissue RNA - basal ganglia [nTPM]":"4.6","Tissue RNA - bone marrow [nTPM]":"8.8","Tissue RNA - breast [nTPM]":"10.9","Tissue RNA - cerebellum [nTPM]":"5.2","Tissue RNA - cerebral cortex [nTPM]":"6.8","Tissue RNA - cervix [nTPM]":"7.3","Tissue RNA - choroid plexus [nTPM]":"22.1","Tissue RNA - colon [nTPM]":"10.6","Tissue RNA - duodenum [nTPM]":"20.8","Tissue RNA - endometrium 1 [nTPM]":"7.6","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"8.7","Tissue RNA - fallopian tube [nTPM]":"7.7","Tissue RNA - gallbladder [nTPM]":"3.3","Tissue RNA - heart muscle [nTPM]":"9.3","Tissue RNA - hippocampal formation [nTPM]":"3.8","Tissue RNA - hypothalamus [nTPM]":"4.9","Tissue RNA - kidney [nTPM]":"11.2","Tissue RNA - liver [nTPM]":"12.3","Tissue RNA - lung [nTPM]":"15.5","Tissue RNA - lymph node [nTPM]":"12.0","Tissue RNA - medulla oblongata [nTPM]":"5.5","Tissue RNA - midbrain [nTPM]":"4.9","Tissue RNA - ovary [nTPM]":"6.7","Tissue RNA - pancreas [nTPM]":"8.1","Tissue RNA - parathyroid gland [nTPM]":"8.7","Tissue RNA - pituitary gland [nTPM]":"2.6","Tissue RNA - placenta [nTPM]":"4.5","Tissue RNA - pons [nTPM]":"5.5","Tissue RNA - prostate [nTPM]":"6.4","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"15.6","Tissue RNA - seminal vesicle [nTPM]":"2.6","Tissue RNA - skeletal muscle [nTPM]":"60.1","Tissue RNA - skin 1 [nTPM]":"46.6","Tissue RNA - small intestine [nTPM]":"13.8","Tissue RNA - smooth muscle [nTPM]":"2.2","Tissue RNA - spinal cord [nTPM]":"5.4","Tissue RNA - spleen [nTPM]":"23.1","Tissue RNA - stomach 1 [nTPM]":"12.5","Tissue RNA - testis [nTPM]":"11.5","Tissue RNA - thalamus [nTPM]":"5.1","Tissue RNA - thymus [nTPM]":"6.1","Tissue RNA - thyroid gland [nTPM]":"10.4","Tissue RNA - tongue [nTPM]":"14.0","Tissue RNA - tonsil [nTPM]":"2.8","Tissue RNA - urinary bladder [nTPM]":"11.1","Tissue RNA - vagina [nTPM]":"7.8","Tissue RNA - white matter [nTPM]":"5.1","Cell RNA - A-431 [nTPM]":"18.3","Cell RNA - A549 [nTPM]":"42.0","Cell RNA - AF22 [nTPM]":"3.4","Cell RNA - AN3-CA [nTPM]":"16.9","Cell RNA - ASC diff [nTPM]":"4.0","Cell RNA - ASC TERT1 [nTPM]":"4.9","Cell RNA - BEWO [nTPM]":"18.4","Cell RNA - BJ [nTPM]":"20.5","Cell RNA - BJ hTERT+ [nTPM]":"2.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.7","Cell RNA - CACO-2 [nTPM]":"33.1","Cell RNA - CAPAN-2 [nTPM]":"16.2","Cell RNA - Daudi [nTPM]":"13.3","Cell RNA - EFO-21 [nTPM]":"31.4","Cell RNA - fHDF\/TERT166 [nTPM]":"3.1","Cell RNA - GAMG [nTPM]":"11.8","Cell RNA - HaCaT [nTPM]":"30.2","Cell RNA - HAP1 [nTPM]":"3.4","Cell RNA - HBEC3-KT [nTPM]":"13.7","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"41.9","Cell RNA - HEK 293 [nTPM]":"7.8","Cell RNA - HEL [nTPM]":"23.9","Cell RNA - HeLa [nTPM]":"6.8","Cell RNA - Hep G2 [nTPM]":"16.6","Cell RNA - HHSteC [nTPM]":"10.1","Cell RNA - HL-60 [nTPM]":"18.5","Cell RNA - HMC-1 [nTPM]":"43.7","Cell RNA - HSkMC [nTPM]":"2.0","Cell RNA - hTCEpi [nTPM]":"5.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.4","Cell RNA - hTERT-HME1 [nTPM]":"0.9","Cell RNA - hTERT-RPE1 [nTPM]":"4.9","Cell RNA - HUVEC TERT2 [nTPM]":"12.9","Cell RNA - JURKAT [nTPM]":"30.0","Cell RNA - K-562 [nTPM]":"16.8","Cell RNA - Karpas-707 [nTPM]":"6.9","Cell RNA - LHCN-M2 [nTPM]":"2.3","Cell RNA - MCF7 [nTPM]":"41.4","Cell RNA - MOLT-4 [nTPM]":"46.1","Cell RNA - NB-4 [nTPM]":"81.7","Cell RNA - NTERA-2 [nTPM]":"19.6","Cell RNA - OE19 [nTPM]":"10.3","Cell RNA - PC-3 [nTPM]":"35.7","Cell RNA - REH [nTPM]":"16.8","Cell RNA - RH-30 [nTPM]":"7.9","Cell RNA - RPMI-8226 [nTPM]":"20.5","Cell RNA - RPTEC TERT1 [nTPM]":"5.0","Cell RNA - RT4 [nTPM]":"13.4","Cell RNA - SCLC-21H [nTPM]":"16.4","Cell RNA - SH-SY5Y [nTPM]":"3.3","Cell RNA - SiHa [nTPM]":"10.7","Cell RNA - SK-BR-3 [nTPM]":"11.7","Cell RNA - SK-MEL-30 [nTPM]":"17.5","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"29.3","Cell RNA - THP-1 [nTPM]":"11.6","Cell RNA - TIME [nTPM]":"23.5","Cell RNA - U-138 MG [nTPM]":"21.0","Cell RNA - U-2 OS [nTPM]":"8.4","Cell RNA - U-2197 [nTPM]":"28.6","Cell RNA - U-251 MG [nTPM]":"15.9","Cell RNA - U-266\/70 [nTPM]":"9.4","Cell RNA - U-266\/84 [nTPM]":"8.7","Cell RNA - U-698 [nTPM]":"5.6","Cell RNA - U-87 MG [nTPM]":"15.7","Cell RNA - U-937 [nTPM]":"25.9","Cell RNA - WM-115 [nTPM]":"19.1","Blood RNA - basophil [nTPM]":"9.4","Blood RNA - classical monocyte [nTPM]":"6.3","Blood RNA - eosinophil [nTPM]":"8.2","Blood RNA - gdT-cell [nTPM]":"18.6","Blood RNA - intermediate monocyte [nTPM]":"5.4","Blood RNA - MAIT T-cell [nTPM]":"13.9","Blood RNA - memory B-cell [nTPM]":"6.3","Blood RNA - memory CD4 T-cell [nTPM]":"15.4","Blood RNA - memory CD8 T-cell [nTPM]":"18.8","Blood RNA - myeloid DC [nTPM]":"7.5","Blood RNA - naive B-cell [nTPM]":"9.0","Blood RNA - naive CD4 T-cell [nTPM]":"14.3","Blood RNA - naive CD8 T-cell [nTPM]":"12.5","Blood RNA - neutrophil [nTPM]":"6.9","Blood RNA - NK-cell [nTPM]":"7.5","Blood RNA - non-classical monocyte [nTPM]":"5.2","Blood RNA - plasmacytoid DC [nTPM]":"1.9","Blood RNA - T-reg [nTPM]":"13.7","Blood RNA - total PBMC [nTPM]":"7.6","Brain RNA - amygdala [nTPM]":"4.4","Brain RNA - basal ganglia [nTPM]":"4.6","Brain RNA - cerebellum [nTPM]":"5.2","Brain RNA - cerebral cortex [nTPM]":"6.8","Brain RNA - hippocampal formation [nTPM]":"3.8","Brain RNA - hypothalamus [nTPM]":"4.9","Brain RNA - medulla oblongata [nTPM]":"5.5","Brain RNA - midbrain [nTPM]":"4.9","Brain RNA - pons [nTPM]":"5.5","Brain RNA - spinal cord [nTPM]":"5.4","Brain RNA - thalamus [nTPM]":"5.1","Brain RNA - white matter [nTPM]":"5.1","Single Cell Type RNA - Adipocytes [nTPM]":"32.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.4","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"41.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"22.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"2.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"48.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"22.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"10.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.7","Single Cell Type RNA - dendritic cells [nTPM]":"92.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"13.3","Single Cell Type RNA - Early spermatids [nTPM]":"3.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.1","Single Cell Type RNA - Endothelial cells [nTPM]":"40.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"23.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.2","Single Cell Type RNA - Fibroblasts [nTPM]":"9.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.4","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"24.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"43.2","Single Cell Type RNA - Hepatocytes [nTPM]":"17.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"38.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.3","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"28.2","Single Cell Type RNA - Langerhans cells [nTPM]":"65.0","Single Cell Type RNA - Late spermatids [nTPM]":"11.8","Single Cell Type RNA - Leydig cells [nTPM]":"13.4","Single Cell Type RNA - Macrophages [nTPM]":"42.8","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"27.2","Single Cell Type RNA - Muller glia cells [nTPM]":"5.8","Single Cell Type RNA - NK-cells [nTPM]":"88.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.5","Single Cell Type RNA - Paneth cells [nTPM]":"6.3","Single Cell Type RNA - Peritubular cells [nTPM]":"9.4","Single Cell Type RNA - Plasma cells [nTPM]":"30.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.8","Single Cell Type RNA - Spermatocytes [nTPM]":"1.7","Single Cell Type RNA - Spermatogonia [nTPM]":"6.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"37.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.8","Single Cell Type RNA - T-cells [nTPM]":"70.3","Single Cell Type RNA - Theca cells [nTPM]":"86.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.1","Single Cell Type RNA - Urothelial cells [nTPM]":"10.7"},{"Gene":"OSGEP","Gene synonym":["GCPL1","KAE1","OSGEP1","PRSMG1","TCS3"],"Ensembl":"ENSG00000092094","Gene description":"O-sialoglycoprotein endopeptidase","Uniprot":["Q9NPF4"],"Chromosome":"14","Position":"20446401-20455089","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["tRNA processing"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039751"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA039751":"AB_10794754"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.48e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.64e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.91e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.7","Tissue RNA - adrenal gland [nTPM]":"6.3","Tissue RNA - amygdala [nTPM]":"6.1","Tissue RNA - appendix [nTPM]":"3.8","Tissue RNA - basal ganglia [nTPM]":"6.2","Tissue RNA - bone marrow [nTPM]":"6.1","Tissue RNA - breast [nTPM]":"7.0","Tissue RNA - cerebellum [nTPM]":"6.4","Tissue RNA - cerebral cortex [nTPM]":"7.3","Tissue RNA - cervix [nTPM]":"6.8","Tissue RNA - choroid plexus [nTPM]":"6.8","Tissue RNA - colon [nTPM]":"7.6","Tissue RNA - duodenum [nTPM]":"3.8","Tissue RNA - endometrium 1 [nTPM]":"6.4","Tissue RNA - epididymis [nTPM]":"8.5","Tissue RNA - esophagus [nTPM]":"6.0","Tissue RNA - fallopian tube [nTPM]":"6.1","Tissue RNA - gallbladder [nTPM]":"6.6","Tissue RNA - heart muscle [nTPM]":"8.1","Tissue RNA - hippocampal formation [nTPM]":"6.0","Tissue RNA - hypothalamus [nTPM]":"6.3","Tissue RNA - kidney [nTPM]":"5.8","Tissue RNA - liver [nTPM]":"11.1","Tissue RNA - lung [nTPM]":"6.2","Tissue RNA - lymph node [nTPM]":"9.3","Tissue RNA - medulla oblongata [nTPM]":"6.4","Tissue RNA - midbrain [nTPM]":"6.1","Tissue RNA - ovary [nTPM]":"5.3","Tissue RNA - pancreas [nTPM]":"5.6","Tissue RNA - parathyroid gland [nTPM]":"7.4","Tissue RNA - pituitary gland [nTPM]":"5.2","Tissue RNA - placenta [nTPM]":"6.7","Tissue RNA - pons [nTPM]":"6.4","Tissue RNA - prostate [nTPM]":"4.9","Tissue RNA - rectum [nTPM]":"7.0","Tissue RNA - retina [nTPM]":"4.1","Tissue RNA - salivary gland [nTPM]":"5.3","Tissue RNA - seminal vesicle [nTPM]":"8.3","Tissue RNA - skeletal muscle [nTPM]":"10.5","Tissue RNA - skin 1 [nTPM]":"4.7","Tissue RNA - small intestine [nTPM]":"6.2","Tissue RNA - smooth muscle [nTPM]":"5.6","Tissue RNA - spinal cord [nTPM]":"6.5","Tissue RNA - spleen [nTPM]":"8.4","Tissue RNA - stomach 1 [nTPM]":"6.4","Tissue RNA - testis [nTPM]":"2.4","Tissue RNA - thalamus [nTPM]":"6.3","Tissue RNA - thymus [nTPM]":"9.9","Tissue RNA - thyroid gland [nTPM]":"7.6","Tissue RNA - tongue [nTPM]":"9.9","Tissue RNA - tonsil [nTPM]":"10.1","Tissue RNA - urinary bladder [nTPM]":"8.2","Tissue RNA - vagina [nTPM]":"4.9","Tissue RNA - white matter [nTPM]":"6.9","Cell RNA - A-431 [nTPM]":"10.3","Cell RNA - A549 [nTPM]":"17.2","Cell RNA - AF22 [nTPM]":"5.6","Cell RNA - AN3-CA [nTPM]":"16.2","Cell RNA - ASC diff [nTPM]":"9.9","Cell RNA - ASC TERT1 [nTPM]":"6.6","Cell RNA - BEWO [nTPM]":"17.6","Cell RNA - BJ [nTPM]":"8.0","Cell RNA - BJ hTERT+ [nTPM]":"11.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.1","Cell RNA - CACO-2 [nTPM]":"21.5","Cell RNA - CAPAN-2 [nTPM]":"12.3","Cell RNA - Daudi [nTPM]":"21.1","Cell RNA - EFO-21 [nTPM]":"10.3","Cell RNA - fHDF\/TERT166 [nTPM]":"11.0","Cell RNA - GAMG [nTPM]":"9.0","Cell RNA - HaCaT [nTPM]":"8.6","Cell RNA - HAP1 [nTPM]":"17.9","Cell RNA - HBEC3-KT [nTPM]":"17.6","Cell RNA - HBF TERT88 [nTPM]":"14.1","Cell RNA - HDLM-2 [nTPM]":"16.8","Cell RNA - HEK 293 [nTPM]":"19.1","Cell RNA - HEL [nTPM]":"14.8","Cell RNA - HeLa [nTPM]":"12.2","Cell RNA - Hep G2 [nTPM]":"32.1","Cell RNA - HHSteC [nTPM]":"7.4","Cell RNA - HL-60 [nTPM]":"24.3","Cell RNA - HMC-1 [nTPM]":"19.7","Cell RNA - HSkMC [nTPM]":"5.3","Cell RNA - hTCEpi [nTPM]":"5.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.1","Cell RNA - hTERT-HME1 [nTPM]":"14.0","Cell RNA - hTERT-RPE1 [nTPM]":"4.6","Cell RNA - HUVEC TERT2 [nTPM]":"14.3","Cell RNA - JURKAT [nTPM]":"18.8","Cell RNA - K-562 [nTPM]":"14.0","Cell RNA - Karpas-707 [nTPM]":"12.1","Cell RNA - LHCN-M2 [nTPM]":"17.6","Cell RNA - MCF7 [nTPM]":"21.0","Cell RNA - MOLT-4 [nTPM]":"25.0","Cell RNA - NB-4 [nTPM]":"11.8","Cell RNA - NTERA-2 [nTPM]":"9.1","Cell RNA - OE19 [nTPM]":"31.5","Cell RNA - PC-3 [nTPM]":"31.8","Cell RNA - REH [nTPM]":"35.3","Cell RNA - RH-30 [nTPM]":"10.3","Cell RNA - RPMI-8226 [nTPM]":"12.4","Cell RNA - RPTEC TERT1 [nTPM]":"12.8","Cell RNA - RT4 [nTPM]":"11.7","Cell RNA - SCLC-21H [nTPM]":"21.3","Cell RNA - SH-SY5Y [nTPM]":"4.2","Cell RNA - SiHa [nTPM]":"15.4","Cell RNA - SK-BR-3 [nTPM]":"16.0","Cell RNA - SK-MEL-30 [nTPM]":"11.9","Cell RNA - SuSa [nTPM]":"3.3","Cell RNA - T-47d [nTPM]":"9.7","Cell RNA - THP-1 [nTPM]":"23.7","Cell RNA - TIME [nTPM]":"6.1","Cell RNA - U-138 MG [nTPM]":"8.7","Cell RNA - U-2 OS [nTPM]":"21.2","Cell RNA - U-2197 [nTPM]":"11.3","Cell RNA - U-251 MG [nTPM]":"10.7","Cell RNA - U-266\/70 [nTPM]":"3.4","Cell RNA - U-266\/84 [nTPM]":"18.0","Cell RNA - U-698 [nTPM]":"31.7","Cell RNA - U-87 MG [nTPM]":"5.0","Cell RNA - U-937 [nTPM]":"36.1","Cell RNA - WM-115 [nTPM]":"11.0","Blood RNA - basophil [nTPM]":"9.3","Blood RNA - classical monocyte [nTPM]":"29.2","Blood RNA - eosinophil [nTPM]":"38.5","Blood RNA - gdT-cell [nTPM]":"18.8","Blood RNA - intermediate monocyte [nTPM]":"27.9","Blood RNA - MAIT T-cell [nTPM]":"17.4","Blood RNA - memory B-cell [nTPM]":"28.7","Blood RNA - memory CD4 T-cell [nTPM]":"19.7","Blood RNA - memory CD8 T-cell [nTPM]":"17.2","Blood RNA - myeloid DC [nTPM]":"44.5","Blood RNA - naive B-cell [nTPM]":"38.1","Blood RNA - naive CD4 T-cell [nTPM]":"15.9","Blood RNA - naive CD8 T-cell [nTPM]":"17.4","Blood RNA - neutrophil [nTPM]":"13.8","Blood RNA - NK-cell [nTPM]":"20.9","Blood RNA - non-classical monocyte [nTPM]":"23.3","Blood RNA - plasmacytoid DC [nTPM]":"16.9","Blood RNA - T-reg [nTPM]":"19.2","Blood RNA - total PBMC [nTPM]":"24.6","Brain RNA - amygdala [nTPM]":"6.1","Brain RNA - basal ganglia [nTPM]":"6.2","Brain RNA - cerebellum [nTPM]":"6.4","Brain RNA - cerebral cortex [nTPM]":"7.3","Brain RNA - hippocampal formation [nTPM]":"6.0","Brain RNA - hypothalamus [nTPM]":"6.3","Brain RNA - medulla oblongata [nTPM]":"6.4","Brain RNA - midbrain [nTPM]":"6.1","Brain RNA - pons [nTPM]":"6.4","Brain RNA - spinal cord [nTPM]":"6.5","Brain RNA - thalamus [nTPM]":"6.3","Brain RNA - white matter [nTPM]":"6.9","Single Cell Type RNA - Adipocytes [nTPM]":"27.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"34.9","Single Cell Type RNA - Astrocytes [nTPM]":"16.3","Single Cell Type RNA - B-cells [nTPM]":"46.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"26.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"37.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"24.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"25.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"29.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"66.3","Single Cell Type RNA - dendritic cells [nTPM]":"31.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"22.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"24.7","Single Cell Type RNA - Early spermatids [nTPM]":"3.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.3","Single Cell Type RNA - Endothelial cells [nTPM]":"24.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"26.9","Single Cell Type RNA - Erythroid cells [nTPM]":"19.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"29.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"47.0","Single Cell Type RNA - Fibroblasts [nTPM]":"23.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"28.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.3","Single Cell Type RNA - granulocytes [nTPM]":"25.9","Single Cell Type RNA - Granulosa cells [nTPM]":"24.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.7","Single Cell Type RNA - Hepatocytes [nTPM]":"19.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"65.8","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.2","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"30.7","Single Cell Type RNA - Langerhans cells [nTPM]":"32.8","Single Cell Type RNA - Late spermatids [nTPM]":"3.0","Single Cell Type RNA - Leydig cells [nTPM]":"19.3","Single Cell Type RNA - Macrophages [nTPM]":"34.2","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"28.4","Single Cell Type RNA - Muller glia cells [nTPM]":"31.0","Single Cell Type RNA - NK-cells [nTPM]":"32.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.0","Single Cell Type RNA - Paneth cells [nTPM]":"30.6","Single Cell Type RNA - Peritubular cells [nTPM]":"21.4","Single Cell Type RNA - Plasma cells [nTPM]":"26.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"42.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"39.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"25.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"51.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"24.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.9","Single Cell Type RNA - Spermatocytes [nTPM]":"7.8","Single Cell Type RNA - Spermatogonia [nTPM]":"16.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"46.1","Single Cell Type RNA - T-cells [nTPM]":"26.8","Single Cell Type RNA - Theca cells [nTPM]":"37.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"31.6","Single Cell Type RNA - Urothelial cells [nTPM]":"17.4"},{"Gene":"OSTM1","Gene synonym":["GL","HSPC019"],"Ensembl":"ENSG00000081087","Gene description":"Osteoclastogenesis associated transmembrane protein 1","Uniprot":["Q86WC4"],"Chromosome":"6","Position":"108041409-108165854","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Osteopetrosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Melanocytes":"151.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010851"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"210000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm","Vesicles"],"Antibody RRID":{"HPA010851":"AB_1079533"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.36e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.26e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.34e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.20e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Tissue RNA - adipose tissue [nTPM]":"26.1","Tissue RNA - adrenal gland [nTPM]":"19.1","Tissue RNA - amygdala [nTPM]":"4.7","Tissue RNA - appendix [nTPM]":"17.9","Tissue RNA - basal ganglia [nTPM]":"5.2","Tissue RNA - bone marrow [nTPM]":"5.7","Tissue RNA - breast [nTPM]":"9.8","Tissue RNA - cerebellum [nTPM]":"5.1","Tissue RNA - cerebral cortex [nTPM]":"5.8","Tissue RNA - cervix [nTPM]":"10.4","Tissue RNA - choroid plexus [nTPM]":"33.1","Tissue RNA - colon [nTPM]":"12.2","Tissue RNA - duodenum [nTPM]":"7.9","Tissue RNA - endometrium 1 [nTPM]":"13.7","Tissue RNA - epididymis [nTPM]":"9.0","Tissue RNA - esophagus [nTPM]":"12.7","Tissue RNA - fallopian tube [nTPM]":"9.5","Tissue RNA - gallbladder [nTPM]":"12.5","Tissue RNA - heart muscle [nTPM]":"19.2","Tissue RNA - hippocampal formation [nTPM]":"5.3","Tissue RNA - hypothalamus [nTPM]":"9.2","Tissue RNA - kidney [nTPM]":"15.6","Tissue RNA - liver [nTPM]":"13.1","Tissue RNA - lung [nTPM]":"16.2","Tissue RNA - lymph node [nTPM]":"14.7","Tissue RNA - medulla oblongata [nTPM]":"6.0","Tissue RNA - midbrain [nTPM]":"7.6","Tissue RNA - ovary [nTPM]":"7.5","Tissue RNA - pancreas [nTPM]":"5.8","Tissue RNA - parathyroid gland [nTPM]":"15.3","Tissue RNA - pituitary gland [nTPM]":"8.3","Tissue RNA - placenta [nTPM]":"14.1","Tissue RNA - pons [nTPM]":"7.9","Tissue RNA - prostate [nTPM]":"13.8","Tissue RNA - rectum [nTPM]":"11.1","Tissue RNA - retina [nTPM]":"17.6","Tissue RNA - salivary gland [nTPM]":"8.9","Tissue RNA - seminal vesicle [nTPM]":"16.7","Tissue RNA - skeletal muscle [nTPM]":"11.8","Tissue RNA - skin 1 [nTPM]":"9.8","Tissue RNA - small intestine [nTPM]":"9.0","Tissue RNA - smooth muscle [nTPM]":"23.3","Tissue RNA - spinal cord [nTPM]":"5.3","Tissue RNA - spleen [nTPM]":"18.3","Tissue RNA - stomach 1 [nTPM]":"8.5","Tissue RNA - testis [nTPM]":"10.1","Tissue RNA - thalamus [nTPM]":"7.4","Tissue RNA - thymus [nTPM]":"13.7","Tissue RNA - thyroid gland [nTPM]":"10.7","Tissue RNA - tongue [nTPM]":"11.5","Tissue RNA - tonsil [nTPM]":"13.5","Tissue RNA - urinary bladder [nTPM]":"16.9","Tissue RNA - vagina [nTPM]":"7.0","Tissue RNA - white matter [nTPM]":"8.3","Cell RNA - A-431 [nTPM]":"6.0","Cell RNA - A549 [nTPM]":"17.2","Cell RNA - AF22 [nTPM]":"20.1","Cell RNA - AN3-CA [nTPM]":"29.4","Cell RNA - ASC diff [nTPM]":"59.0","Cell RNA - ASC TERT1 [nTPM]":"19.0","Cell RNA - BEWO [nTPM]":"28.6","Cell RNA - BJ [nTPM]":"42.8","Cell RNA - BJ hTERT+ [nTPM]":"42.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"30.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"50.4","Cell RNA - CACO-2 [nTPM]":"10.0","Cell RNA - CAPAN-2 [nTPM]":"9.8","Cell RNA - Daudi [nTPM]":"13.7","Cell RNA - EFO-21 [nTPM]":"34.4","Cell RNA - fHDF\/TERT166 [nTPM]":"30.0","Cell RNA - GAMG [nTPM]":"82.5","Cell RNA - HaCaT [nTPM]":"11.1","Cell RNA - HAP1 [nTPM]":"20.2","Cell RNA - HBEC3-KT [nTPM]":"14.6","Cell RNA - HBF TERT88 [nTPM]":"47.0","Cell RNA - HDLM-2 [nTPM]":"31.6","Cell RNA - HEK 293 [nTPM]":"15.7","Cell RNA - HEL [nTPM]":"28.9","Cell RNA - HeLa [nTPM]":"10.9","Cell RNA - Hep G2 [nTPM]":"12.8","Cell RNA - HHSteC [nTPM]":"45.6","Cell RNA - HL-60 [nTPM]":"32.1","Cell RNA - HMC-1 [nTPM]":"64.6","Cell RNA - HSkMC [nTPM]":"28.1","Cell RNA - hTCEpi [nTPM]":"35.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"37.7","Cell RNA - hTERT-HME1 [nTPM]":"30.0","Cell RNA - hTERT-RPE1 [nTPM]":"28.2","Cell RNA - HUVEC TERT2 [nTPM]":"15.8","Cell RNA - JURKAT [nTPM]":"15.2","Cell RNA - K-562 [nTPM]":"23.3","Cell RNA - Karpas-707 [nTPM]":"48.7","Cell RNA - LHCN-M2 [nTPM]":"50.3","Cell RNA - MCF7 [nTPM]":"8.4","Cell RNA - MOLT-4 [nTPM]":"7.1","Cell RNA - NB-4 [nTPM]":"7.3","Cell RNA - NTERA-2 [nTPM]":"8.0","Cell RNA - OE19 [nTPM]":"7.1","Cell RNA - PC-3 [nTPM]":"13.0","Cell RNA - REH [nTPM]":"11.4","Cell RNA - RH-30 [nTPM]":"29.1","Cell RNA - RPMI-8226 [nTPM]":"7.5","Cell RNA - RPTEC TERT1 [nTPM]":"22.0","Cell RNA - RT4 [nTPM]":"15.7","Cell RNA - SCLC-21H [nTPM]":"2.2","Cell RNA - SH-SY5Y [nTPM]":"11.8","Cell RNA - SiHa [nTPM]":"34.7","Cell RNA - SK-BR-3 [nTPM]":"8.7","Cell RNA - SK-MEL-30 [nTPM]":"79.9","Cell RNA - SuSa [nTPM]":"26.6","Cell RNA - T-47d [nTPM]":"10.0","Cell RNA - THP-1 [nTPM]":"45.8","Cell RNA - TIME [nTPM]":"19.3","Cell RNA - U-138 MG [nTPM]":"26.7","Cell RNA - U-2 OS [nTPM]":"9.8","Cell RNA - U-2197 [nTPM]":"59.7","Cell RNA - U-251 MG [nTPM]":"61.4","Cell RNA - U-266\/70 [nTPM]":"18.6","Cell RNA - U-266\/84 [nTPM]":"34.4","Cell RNA - U-698 [nTPM]":"11.9","Cell RNA - U-87 MG [nTPM]":"78.9","Cell RNA - U-937 [nTPM]":"21.3","Cell RNA - WM-115 [nTPM]":"60.3","Blood RNA - basophil [nTPM]":"31.4","Blood RNA - classical monocyte [nTPM]":"20.2","Blood RNA - eosinophil [nTPM]":"22.8","Blood RNA - gdT-cell [nTPM]":"20.3","Blood RNA - intermediate monocyte [nTPM]":"29.4","Blood RNA - MAIT T-cell [nTPM]":"21.5","Blood RNA - memory B-cell [nTPM]":"14.7","Blood RNA - memory CD4 T-cell [nTPM]":"16.9","Blood RNA - memory CD8 T-cell [nTPM]":"22.3","Blood RNA - myeloid DC [nTPM]":"17.8","Blood RNA - naive B-cell [nTPM]":"8.6","Blood RNA - naive CD4 T-cell [nTPM]":"15.6","Blood RNA - naive CD8 T-cell [nTPM]":"19.8","Blood RNA - neutrophil [nTPM]":"29.8","Blood RNA - NK-cell [nTPM]":"22.0","Blood RNA - non-classical monocyte [nTPM]":"43.5","Blood RNA - plasmacytoid DC [nTPM]":"12.9","Blood RNA - T-reg [nTPM]":"22.6","Blood RNA - total PBMC [nTPM]":"27.0","Brain RNA - amygdala [nTPM]":"4.7","Brain RNA - basal ganglia [nTPM]":"5.2","Brain RNA - cerebellum [nTPM]":"5.1","Brain RNA - cerebral cortex [nTPM]":"5.8","Brain RNA - hippocampal formation [nTPM]":"5.3","Brain RNA - hypothalamus [nTPM]":"9.2","Brain RNA - medulla oblongata [nTPM]":"6.0","Brain RNA - midbrain [nTPM]":"7.6","Brain RNA - pons [nTPM]":"7.9","Brain RNA - spinal cord [nTPM]":"5.3","Brain RNA - thalamus [nTPM]":"7.4","Brain RNA - white matter [nTPM]":"8.3","Single Cell Type RNA - Adipocytes [nTPM]":"28.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.0","Single Cell Type RNA - Astrocytes [nTPM]":"26.4","Single Cell Type RNA - B-cells [nTPM]":"26.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"46.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"19.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.6","Single Cell Type RNA - Bipolar cells [nTPM]":"28.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"24.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"9.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"21.7","Single Cell Type RNA - dendritic cells [nTPM]":"32.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"21.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"12.4","Single Cell Type RNA - Early spermatids [nTPM]":"12.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.7","Single Cell Type RNA - Endothelial cells [nTPM]":"20.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"4.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"36.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"22.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"33.9","Single Cell Type RNA - Fibroblasts [nTPM]":"24.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.6","Single Cell Type RNA - granulocytes [nTPM]":"24.1","Single Cell Type RNA - Granulosa cells [nTPM]":"6.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.7","Single Cell Type RNA - Hepatocytes [nTPM]":"13.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"52.8","Single Cell Type RNA - Horizontal cells [nTPM]":"28.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"40.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.8","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"46.5","Single Cell Type RNA - Langerhans cells [nTPM]":"29.5","Single Cell Type RNA - Late spermatids [nTPM]":"5.4","Single Cell Type RNA - Leydig cells [nTPM]":"14.3","Single Cell Type RNA - Macrophages [nTPM]":"43.1","Single Cell Type RNA - Melanocytes [nTPM]":"151.2","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"25.6","Single Cell Type RNA - Muller glia cells [nTPM]":"23.7","Single Cell Type RNA - NK-cells [nTPM]":"40.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"21.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"36.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.8","Single Cell Type RNA - Paneth cells [nTPM]":"17.0","Single Cell Type RNA - Peritubular cells [nTPM]":"28.6","Single Cell Type RNA - Plasma cells [nTPM]":"25.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"25.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.5","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"29.6","Single Cell Type RNA - Spermatocytes [nTPM]":"28.0","Single Cell Type RNA - Spermatogonia [nTPM]":"18.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"31.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"61.2","Single Cell Type RNA - T-cells [nTPM]":"29.5","Single Cell Type RNA - Theca cells [nTPM]":"23.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.3","Single Cell Type RNA - Urothelial cells [nTPM]":"16.0"},{"Gene":"OTC","Gene synonym":["OTCase"],"Ensembl":"ENSG00000036473","Gene description":"Ornithine carbamoyltransferase","Uniprot":["P00480"],"Chromosome":"X","Position":"38352586-38421446","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Amino-acid biosynthesis","Arginine biosynthesis","Urea cycle"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"124","RNA tissue specific nTPM":{"intestine":"112.4","liver":"377.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Hepatic stellate cells":"38.9","Hepatocytes":"99.6","Proximal enterocytes":"82.0","Undifferentiated cells":"25.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"20","RNA cancer specific FPKM":{"liver cancer":"59.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000243","HPA000570"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2200000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA000243":"AB_1079535","HPA000570":"AB_1079534"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"1.2","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"5.0","Tissue RNA - duodenum [nTPM]":"112.4","Tissue RNA - endometrium 1 [nTPM]":"0.7","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"377.8","Tissue RNA - lung [nTPM]":"0.9","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"1.7","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"2.5","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"87.4","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"1.9","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"7.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"38.9","Single Cell Type RNA - Hepatocytes [nTPM]":"99.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.5","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"10.9","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"82.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"25.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"OTUD6B","Gene synonym":["CGI-77","DUBA5"],"Ensembl":"ENSG00000155100","Gene description":"OTU deubiquitinase 6B","Uniprot":["Q8N6M0"],"Chromosome":"8","Position":"91070196-91087095","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024046","HPA024503","HPA024772"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA024046":"AB_10600925","HPA024503":"AB_1854845","HPA024772":"AB_1854846"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.50e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.61e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.6","Tissue RNA - adrenal gland [nTPM]":"6.2","Tissue RNA - amygdala [nTPM]":"5.7","Tissue RNA - appendix [nTPM]":"6.3","Tissue RNA - basal ganglia [nTPM]":"6.1","Tissue RNA - bone marrow [nTPM]":"5.9","Tissue RNA - breast [nTPM]":"7.2","Tissue RNA - cerebellum [nTPM]":"5.9","Tissue RNA - cerebral cortex [nTPM]":"8.6","Tissue RNA - cervix [nTPM]":"5.2","Tissue RNA - choroid plexus [nTPM]":"5.0","Tissue RNA - colon [nTPM]":"5.3","Tissue RNA - duodenum [nTPM]":"4.2","Tissue RNA - endometrium 1 [nTPM]":"6.0","Tissue RNA - epididymis [nTPM]":"4.6","Tissue RNA - esophagus [nTPM]":"6.4","Tissue RNA - fallopian tube [nTPM]":"4.2","Tissue RNA - gallbladder [nTPM]":"3.9","Tissue RNA - heart muscle [nTPM]":"6.5","Tissue RNA - hippocampal formation [nTPM]":"5.4","Tissue RNA - hypothalamus [nTPM]":"6.1","Tissue RNA - kidney [nTPM]":"5.4","Tissue RNA - liver [nTPM]":"5.4","Tissue RNA - lung [nTPM]":"4.7","Tissue RNA - lymph node [nTPM]":"7.4","Tissue RNA - medulla oblongata [nTPM]":"6.2","Tissue RNA - midbrain [nTPM]":"6.2","Tissue RNA - ovary [nTPM]":"5.3","Tissue RNA - pancreas [nTPM]":"4.6","Tissue RNA - parathyroid gland [nTPM]":"4.0","Tissue RNA - pituitary gland [nTPM]":"3.5","Tissue RNA - placenta [nTPM]":"8.0","Tissue RNA - pons [nTPM]":"6.3","Tissue RNA - prostate [nTPM]":"5.8","Tissue RNA - rectum [nTPM]":"5.4","Tissue RNA - retina [nTPM]":"3.1","Tissue RNA - salivary gland [nTPM]":"4.3","Tissue RNA - seminal vesicle [nTPM]":"4.7","Tissue RNA - skeletal muscle [nTPM]":"10.2","Tissue RNA - skin 1 [nTPM]":"6.4","Tissue RNA - small intestine [nTPM]":"4.4","Tissue RNA - smooth muscle [nTPM]":"5.5","Tissue RNA - spinal cord [nTPM]":"6.3","Tissue RNA - spleen [nTPM]":"5.0","Tissue RNA - stomach 1 [nTPM]":"4.3","Tissue RNA - testis [nTPM]":"6.4","Tissue RNA - thalamus [nTPM]":"5.9","Tissue RNA - thymus [nTPM]":"5.7","Tissue RNA - thyroid gland [nTPM]":"6.0","Tissue RNA - tongue [nTPM]":"9.2","Tissue RNA - tonsil [nTPM]":"6.1","Tissue RNA - urinary bladder [nTPM]":"6.3","Tissue RNA - vagina [nTPM]":"5.4","Tissue RNA - white matter [nTPM]":"7.5","Cell RNA - A-431 [nTPM]":"27.6","Cell RNA - A549 [nTPM]":"11.1","Cell RNA - AF22 [nTPM]":"12.8","Cell RNA - AN3-CA [nTPM]":"10.4","Cell RNA - ASC diff [nTPM]":"6.4","Cell RNA - ASC TERT1 [nTPM]":"5.6","Cell RNA - BEWO [nTPM]":"14.5","Cell RNA - BJ [nTPM]":"19.1","Cell RNA - BJ hTERT+ [nTPM]":"7.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.6","Cell RNA - CACO-2 [nTPM]":"8.6","Cell RNA - CAPAN-2 [nTPM]":"16.6","Cell RNA - Daudi [nTPM]":"25.6","Cell RNA - EFO-21 [nTPM]":"9.0","Cell RNA - fHDF\/TERT166 [nTPM]":"10.2","Cell RNA - GAMG [nTPM]":"7.6","Cell RNA - HaCaT [nTPM]":"9.1","Cell RNA - HAP1 [nTPM]":"26.4","Cell RNA - HBEC3-KT [nTPM]":"16.1","Cell RNA - HBF TERT88 [nTPM]":"31.6","Cell RNA - HDLM-2 [nTPM]":"21.6","Cell RNA - HEK 293 [nTPM]":"16.9","Cell RNA - HEL [nTPM]":"34.5","Cell RNA - HeLa [nTPM]":"11.7","Cell RNA - Hep G2 [nTPM]":"8.3","Cell RNA - HHSteC [nTPM]":"13.3","Cell RNA - HL-60 [nTPM]":"18.7","Cell RNA - HMC-1 [nTPM]":"21.0","Cell RNA - HSkMC [nTPM]":"7.2","Cell RNA - hTCEpi [nTPM]":"9.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.0","Cell RNA - hTERT-HME1 [nTPM]":"35.5","Cell RNA - hTERT-RPE1 [nTPM]":"11.6","Cell RNA - HUVEC TERT2 [nTPM]":"17.5","Cell RNA - JURKAT [nTPM]":"19.4","Cell RNA - K-562 [nTPM]":"36.5","Cell RNA - Karpas-707 [nTPM]":"19.1","Cell RNA - LHCN-M2 [nTPM]":"18.9","Cell RNA - MCF7 [nTPM]":"9.6","Cell RNA - MOLT-4 [nTPM]":"31.7","Cell RNA - NB-4 [nTPM]":"17.5","Cell RNA - NTERA-2 [nTPM]":"8.1","Cell RNA - OE19 [nTPM]":"20.3","Cell RNA - PC-3 [nTPM]":"27.3","Cell RNA - REH [nTPM]":"19.4","Cell RNA - RH-30 [nTPM]":"11.2","Cell RNA - RPMI-8226 [nTPM]":"28.9","Cell RNA - RPTEC TERT1 [nTPM]":"18.9","Cell RNA - RT4 [nTPM]":"15.1","Cell RNA - SCLC-21H [nTPM]":"3.5","Cell RNA - SH-SY5Y [nTPM]":"14.6","Cell RNA - SiHa [nTPM]":"2.6","Cell RNA - SK-BR-3 [nTPM]":"55.9","Cell RNA - SK-MEL-30 [nTPM]":"22.7","Cell RNA - SuSa [nTPM]":"16.3","Cell RNA - T-47d [nTPM]":"25.5","Cell RNA - THP-1 [nTPM]":"11.8","Cell RNA - TIME [nTPM]":"15.8","Cell RNA - U-138 MG [nTPM]":"12.3","Cell RNA - U-2 OS [nTPM]":"17.2","Cell RNA - U-2197 [nTPM]":"20.6","Cell RNA - U-251 MG [nTPM]":"20.5","Cell RNA - U-266\/70 [nTPM]":"17.1","Cell RNA - U-266\/84 [nTPM]":"29.5","Cell RNA - U-698 [nTPM]":"37.2","Cell RNA - U-87 MG [nTPM]":"16.8","Cell RNA - U-937 [nTPM]":"26.2","Cell RNA - WM-115 [nTPM]":"23.1","Blood RNA - basophil [nTPM]":"1.7","Blood RNA - classical monocyte [nTPM]":"1.9","Blood RNA - eosinophil [nTPM]":"1.1","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"2.7","Blood RNA - MAIT T-cell [nTPM]":"2.0","Blood RNA - memory B-cell [nTPM]":"2.0","Blood RNA - memory CD4 T-cell [nTPM]":"1.4","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"2.6","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"2.1","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"3.4","Blood RNA - non-classical monocyte [nTPM]":"2.1","Blood RNA - plasmacytoid DC [nTPM]":"4.0","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"5.7","Brain RNA - basal ganglia [nTPM]":"6.1","Brain RNA - cerebellum [nTPM]":"5.9","Brain RNA - cerebral cortex [nTPM]":"8.6","Brain RNA - hippocampal formation [nTPM]":"5.4","Brain RNA - hypothalamus [nTPM]":"6.1","Brain RNA - medulla oblongata [nTPM]":"6.2","Brain RNA - midbrain [nTPM]":"6.2","Brain RNA - pons [nTPM]":"6.3","Brain RNA - spinal cord [nTPM]":"6.3","Brain RNA - thalamus [nTPM]":"5.9","Brain RNA - white matter [nTPM]":"7.5","Single Cell Type RNA - Adipocytes [nTPM]":"11.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.3","Single Cell Type RNA - Astrocytes [nTPM]":"9.8","Single Cell Type RNA - B-cells [nTPM]":"13.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"23.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"13.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"9.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.8","Single Cell Type RNA - dendritic cells [nTPM]":"16.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"4.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.9","Single Cell Type RNA - Endothelial cells [nTPM]":"10.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.8","Single Cell Type RNA - Erythroid cells [nTPM]":"8.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.0","Single Cell Type RNA - Fibroblasts [nTPM]":"9.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.6","Single Cell Type RNA - granulocytes [nTPM]":"18.4","Single Cell Type RNA - Granulosa cells [nTPM]":"10.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.9","Single Cell Type RNA - Hepatocytes [nTPM]":"11.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.1","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.9","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"8.7","Single Cell Type RNA - Langerhans cells [nTPM]":"12.5","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"9.6","Single Cell Type RNA - Macrophages [nTPM]":"8.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"10.2","Single Cell Type RNA - Muller glia cells [nTPM]":"12.2","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.6","Single Cell Type RNA - Paneth cells [nTPM]":"3.7","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"12.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.6","Single Cell Type RNA - Spermatocytes [nTPM]":"3.2","Single Cell Type RNA - Spermatogonia [nTPM]":"7.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.7","Single Cell Type RNA - T-cells [nTPM]":"10.7","Single Cell Type RNA - Theca cells [nTPM]":"9.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.4","Single Cell Type RNA - Urothelial cells [nTPM]":"5.9"},{"Gene":"OTULIN","Gene synonym":["FAM105B","FLJ34884"],"Ensembl":"ENSG00000154124","Gene description":"OTU deubiquitinase with linear linkage specificity","Uniprot":["Q96BN8"],"Chromosome":"5","Position":"14664664-14699850","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Angiogenesis","Immunity","Innate immunity","Ubl conjugation pathway","Wnt signaling pathway"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"26.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"70.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051074"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA051074":"AB_2681334"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.59e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.0","Tissue RNA - adrenal gland [nTPM]":"3.9","Tissue RNA - amygdala [nTPM]":"4.8","Tissue RNA - appendix [nTPM]":"9.6","Tissue RNA - basal ganglia [nTPM]":"6.3","Tissue RNA - bone marrow [nTPM]":"26.8","Tissue RNA - breast [nTPM]":"4.6","Tissue RNA - cerebellum [nTPM]":"5.9","Tissue RNA - cerebral cortex [nTPM]":"4.9","Tissue RNA - cervix [nTPM]":"5.5","Tissue RNA - choroid plexus [nTPM]":"6.2","Tissue RNA - colon [nTPM]":"4.7","Tissue RNA - duodenum [nTPM]":"7.6","Tissue RNA - endometrium 1 [nTPM]":"3.6","Tissue RNA - epididymis [nTPM]":"2.6","Tissue RNA - esophagus [nTPM]":"8.0","Tissue RNA - fallopian tube [nTPM]":"3.5","Tissue RNA - gallbladder [nTPM]":"4.7","Tissue RNA - heart muscle [nTPM]":"6.7","Tissue RNA - hippocampal formation [nTPM]":"4.9","Tissue RNA - hypothalamus [nTPM]":"5.0","Tissue RNA - kidney [nTPM]":"4.4","Tissue RNA - liver [nTPM]":"12.3","Tissue RNA - lung [nTPM]":"6.4","Tissue RNA - lymph node [nTPM]":"12.5","Tissue RNA - medulla oblongata [nTPM]":"6.6","Tissue RNA - midbrain [nTPM]":"5.6","Tissue RNA - ovary [nTPM]":"4.8","Tissue RNA - pancreas [nTPM]":"6.8","Tissue RNA - parathyroid gland [nTPM]":"3.8","Tissue RNA - pituitary gland [nTPM]":"3.6","Tissue RNA - placenta [nTPM]":"6.5","Tissue RNA - pons [nTPM]":"6.4","Tissue RNA - prostate [nTPM]":"6.3","Tissue RNA - rectum [nTPM]":"4.6","Tissue RNA - retina [nTPM]":"4.6","Tissue RNA - salivary gland [nTPM]":"5.7","Tissue RNA - seminal vesicle [nTPM]":"3.3","Tissue RNA - skeletal muscle [nTPM]":"5.2","Tissue RNA - skin 1 [nTPM]":"11.8","Tissue RNA - small intestine [nTPM]":"5.8","Tissue RNA - smooth muscle [nTPM]":"4.8","Tissue RNA - spinal cord [nTPM]":"5.6","Tissue RNA - spleen [nTPM]":"7.1","Tissue RNA - stomach 1 [nTPM]":"4.3","Tissue RNA - testis [nTPM]":"7.1","Tissue RNA - thalamus [nTPM]":"5.8","Tissue RNA - thymus [nTPM]":"11.2","Tissue RNA - thyroid gland [nTPM]":"4.1","Tissue RNA - tongue [nTPM]":"5.5","Tissue RNA - tonsil [nTPM]":"13.5","Tissue RNA - urinary bladder [nTPM]":"5.7","Tissue RNA - vagina [nTPM]":"6.9","Tissue RNA - white matter [nTPM]":"7.1","Cell RNA - A-431 [nTPM]":"10.0","Cell RNA - A549 [nTPM]":"11.5","Cell RNA - AF22 [nTPM]":"11.2","Cell RNA - AN3-CA [nTPM]":"12.8","Cell RNA - ASC diff [nTPM]":"10.0","Cell RNA - ASC TERT1 [nTPM]":"10.3","Cell RNA - BEWO [nTPM]":"12.3","Cell RNA - BJ [nTPM]":"9.8","Cell RNA - BJ hTERT+ [nTPM]":"6.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.2","Cell RNA - CACO-2 [nTPM]":"15.4","Cell RNA - CAPAN-2 [nTPM]":"7.2","Cell RNA - Daudi [nTPM]":"18.0","Cell RNA - EFO-21 [nTPM]":"18.9","Cell RNA - fHDF\/TERT166 [nTPM]":"6.4","Cell RNA - GAMG [nTPM]":"19.9","Cell RNA - HaCaT [nTPM]":"11.1","Cell RNA - HAP1 [nTPM]":"14.1","Cell RNA - HBEC3-KT [nTPM]":"12.9","Cell RNA - HBF TERT88 [nTPM]":"9.2","Cell RNA - HDLM-2 [nTPM]":"31.1","Cell RNA - HEK 293 [nTPM]":"11.6","Cell RNA - HEL [nTPM]":"12.9","Cell RNA - HeLa [nTPM]":"36.3","Cell RNA - Hep G2 [nTPM]":"8.3","Cell RNA - HHSteC [nTPM]":"8.8","Cell RNA - HL-60 [nTPM]":"12.4","Cell RNA - HMC-1 [nTPM]":"21.2","Cell RNA - HSkMC [nTPM]":"6.0","Cell RNA - hTCEpi [nTPM]":"15.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.3","Cell RNA - hTERT-HME1 [nTPM]":"9.4","Cell RNA - hTERT-RPE1 [nTPM]":"7.6","Cell RNA - HUVEC TERT2 [nTPM]":"11.8","Cell RNA - JURKAT [nTPM]":"14.9","Cell RNA - K-562 [nTPM]":"13.0","Cell RNA - Karpas-707 [nTPM]":"27.8","Cell RNA - LHCN-M2 [nTPM]":"10.0","Cell RNA - MCF7 [nTPM]":"6.1","Cell RNA - MOLT-4 [nTPM]":"12.4","Cell RNA - NB-4 [nTPM]":"10.6","Cell RNA - NTERA-2 [nTPM]":"6.9","Cell RNA - OE19 [nTPM]":"10.5","Cell RNA - PC-3 [nTPM]":"12.0","Cell RNA - REH [nTPM]":"18.8","Cell RNA - RH-30 [nTPM]":"10.0","Cell RNA - RPMI-8226 [nTPM]":"7.1","Cell RNA - RPTEC TERT1 [nTPM]":"8.9","Cell RNA - RT4 [nTPM]":"10.1","Cell RNA - SCLC-21H [nTPM]":"5.1","Cell RNA - SH-SY5Y [nTPM]":"8.3","Cell RNA - SiHa [nTPM]":"35.1","Cell RNA - SK-BR-3 [nTPM]":"7.8","Cell RNA - SK-MEL-30 [nTPM]":"7.6","Cell RNA - SuSa [nTPM]":"13.5","Cell RNA - T-47d [nTPM]":"8.5","Cell RNA - THP-1 [nTPM]":"14.1","Cell RNA - TIME [nTPM]":"11.1","Cell RNA - U-138 MG [nTPM]":"17.8","Cell RNA - U-2 OS [nTPM]":"20.0","Cell RNA - U-2197 [nTPM]":"13.4","Cell RNA - U-251 MG [nTPM]":"13.2","Cell RNA - U-266\/70 [nTPM]":"12.4","Cell RNA - U-266\/84 [nTPM]":"20.6","Cell RNA - U-698 [nTPM]":"20.3","Cell RNA - U-87 MG [nTPM]":"10.1","Cell RNA - U-937 [nTPM]":"23.2","Cell RNA - WM-115 [nTPM]":"9.3","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"1.1","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"1.0","Blood RNA - naive B-cell [nTPM]":"1.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"1.3","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"1.1","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"1.7","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"4.8","Brain RNA - basal ganglia [nTPM]":"6.3","Brain RNA - cerebellum [nTPM]":"5.9","Brain RNA - cerebral cortex [nTPM]":"4.9","Brain RNA - hippocampal formation [nTPM]":"4.9","Brain RNA - hypothalamus [nTPM]":"5.0","Brain RNA - medulla oblongata [nTPM]":"6.6","Brain RNA - midbrain [nTPM]":"5.6","Brain RNA - pons [nTPM]":"6.4","Brain RNA - spinal cord [nTPM]":"5.6","Brain RNA - thalamus [nTPM]":"5.8","Brain RNA - white matter [nTPM]":"7.1","Single Cell Type RNA - Adipocytes [nTPM]":"20.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.5","Single Cell Type RNA - Astrocytes [nTPM]":"23.5","Single Cell Type RNA - B-cells [nTPM]":"24.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.2","Single Cell Type RNA - Bipolar cells [nTPM]":"11.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"4.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.1","Single Cell Type RNA - dendritic cells [nTPM]":"70.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"21.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.5","Single Cell Type RNA - Early spermatids [nTPM]":"9.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"28.1","Single Cell Type RNA - Endothelial cells [nTPM]":"13.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.5","Single Cell Type RNA - Erythroid cells [nTPM]":"13.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.3","Single Cell Type RNA - Fibroblasts [nTPM]":"10.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.0","Single Cell Type RNA - granulocytes [nTPM]":"10.2","Single Cell Type RNA - Granulosa cells [nTPM]":"14.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"36.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.9","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"19.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"18.9","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"4.2","Single Cell Type RNA - Leydig cells [nTPM]":"10.5","Single Cell Type RNA - Macrophages [nTPM]":"25.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"38.4","Single Cell Type RNA - monocytes [nTPM]":"17.1","Single Cell Type RNA - Muller glia cells [nTPM]":"10.4","Single Cell Type RNA - NK-cells [nTPM]":"26.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"31.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.0","Single Cell Type RNA - Paneth cells [nTPM]":"13.3","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"38.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"25.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"31.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.2","Single Cell Type RNA - Spermatocytes [nTPM]":"29.7","Single Cell Type RNA - Spermatogonia [nTPM]":"28.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.2","Single Cell Type RNA - T-cells [nTPM]":"35.8","Single Cell Type RNA - Theca cells [nTPM]":"7.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.6","Single Cell Type RNA - Urothelial cells [nTPM]":"23.1"},{"Gene":"OXCT1","Gene synonym":["OXCT","SCOT"],"Ensembl":"ENSG00000083720","Gene description":"3-oxoacid CoA-transferase 1","Uniprot":["P55809"],"Chromosome":"5","Position":"41730065-41870425","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"245.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"243.7","Distal tubular cells":"187.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"238.7","SiHa":"319.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012047","HPA061425"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"440000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA012047":"AB_1854857","HPA061425":"AB_2684515"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.03e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.86e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-3"},"Tissue RNA - adipose tissue [nTPM]":"52.7","Tissue RNA - adrenal gland [nTPM]":"15.8","Tissue RNA - amygdala [nTPM]":"30.4","Tissue RNA - appendix [nTPM]":"16.6","Tissue RNA - basal ganglia [nTPM]":"34.9","Tissue RNA - bone marrow [nTPM]":"13.3","Tissue RNA - breast [nTPM]":"18.5","Tissue RNA - cerebellum [nTPM]":"23.9","Tissue RNA - cerebral cortex [nTPM]":"32.7","Tissue RNA - cervix [nTPM]":"13.5","Tissue RNA - choroid plexus [nTPM]":"15.9","Tissue RNA - colon [nTPM]":"19.2","Tissue RNA - duodenum [nTPM]":"8.3","Tissue RNA - endometrium 1 [nTPM]":"14.9","Tissue RNA - epididymis [nTPM]":"17.6","Tissue RNA - esophagus [nTPM]":"26.8","Tissue RNA - fallopian tube [nTPM]":"12.4","Tissue RNA - gallbladder [nTPM]":"15.2","Tissue RNA - heart muscle [nTPM]":"245.9","Tissue RNA - hippocampal formation [nTPM]":"36.2","Tissue RNA - hypothalamus [nTPM]":"27.1","Tissue RNA - kidney [nTPM]":"53.1","Tissue RNA - liver [nTPM]":"1.3","Tissue RNA - lung [nTPM]":"8.0","Tissue RNA - lymph node [nTPM]":"21.7","Tissue RNA - medulla oblongata [nTPM]":"19.5","Tissue RNA - midbrain [nTPM]":"21.4","Tissue RNA - ovary [nTPM]":"13.8","Tissue RNA - pancreas [nTPM]":"5.3","Tissue RNA - parathyroid gland [nTPM]":"48.6","Tissue RNA - pituitary gland [nTPM]":"14.7","Tissue RNA - placenta [nTPM]":"5.0","Tissue RNA - pons [nTPM]":"20.0","Tissue RNA - prostate [nTPM]":"25.5","Tissue RNA - rectum [nTPM]":"21.1","Tissue RNA - retina [nTPM]":"23.6","Tissue RNA - salivary gland [nTPM]":"18.9","Tissue RNA - seminal vesicle [nTPM]":"29.8","Tissue RNA - skeletal muscle [nTPM]":"28.5","Tissue RNA - skin 1 [nTPM]":"23.1","Tissue RNA - small intestine [nTPM]":"12.8","Tissue RNA - smooth muscle [nTPM]":"36.6","Tissue RNA - spinal cord [nTPM]":"19.3","Tissue RNA - spleen [nTPM]":"11.0","Tissue RNA - stomach 1 [nTPM]":"34.2","Tissue RNA - testis [nTPM]":"13.2","Tissue RNA - thalamus [nTPM]":"25.7","Tissue RNA - thymus [nTPM]":"76.8","Tissue RNA - thyroid gland [nTPM]":"27.3","Tissue RNA - tongue [nTPM]":"42.6","Tissue RNA - tonsil [nTPM]":"25.9","Tissue RNA - urinary bladder [nTPM]":"15.1","Tissue RNA - vagina [nTPM]":"13.8","Tissue RNA - white matter [nTPM]":"24.5","Cell RNA - A-431 [nTPM]":"35.3","Cell RNA - A549 [nTPM]":"1.6","Cell RNA - AF22 [nTPM]":"27.9","Cell RNA - AN3-CA [nTPM]":"33.6","Cell RNA - ASC diff [nTPM]":"84.7","Cell RNA - ASC TERT1 [nTPM]":"45.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"62.1","Cell RNA - BJ hTERT+ [nTPM]":"38.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"50.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"30.4","Cell RNA - CACO-2 [nTPM]":"5.7","Cell RNA - CAPAN-2 [nTPM]":"23.5","Cell RNA - Daudi [nTPM]":"91.2","Cell RNA - EFO-21 [nTPM]":"15.0","Cell RNA - fHDF\/TERT166 [nTPM]":"47.5","Cell RNA - GAMG [nTPM]":"25.8","Cell RNA - HaCaT [nTPM]":"20.5","Cell RNA - HAP1 [nTPM]":"77.5","Cell RNA - HBEC3-KT [nTPM]":"55.9","Cell RNA - HBF TERT88 [nTPM]":"58.5","Cell RNA - HDLM-2 [nTPM]":"78.5","Cell RNA - HEK 293 [nTPM]":"9.1","Cell RNA - HEL [nTPM]":"63.9","Cell RNA - HeLa [nTPM]":"238.7","Cell RNA - Hep G2 [nTPM]":"11.9","Cell RNA - HHSteC [nTPM]":"36.8","Cell RNA - HL-60 [nTPM]":"125.8","Cell RNA - HMC-1 [nTPM]":"20.9","Cell RNA - HSkMC [nTPM]":"42.7","Cell RNA - hTCEpi [nTPM]":"15.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"49.3","Cell RNA - hTERT-HME1 [nTPM]":"82.2","Cell RNA - hTERT-RPE1 [nTPM]":"24.6","Cell RNA - HUVEC TERT2 [nTPM]":"46.4","Cell RNA - JURKAT [nTPM]":"81.6","Cell RNA - K-562 [nTPM]":"13.3","Cell RNA - Karpas-707 [nTPM]":"114.0","Cell RNA - LHCN-M2 [nTPM]":"58.1","Cell RNA - MCF7 [nTPM]":"4.5","Cell RNA - MOLT-4 [nTPM]":"105.5","Cell RNA - NB-4 [nTPM]":"6.1","Cell RNA - NTERA-2 [nTPM]":"6.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"24.5","Cell RNA - REH [nTPM]":"82.8","Cell RNA - RH-30 [nTPM]":"78.9","Cell RNA - RPMI-8226 [nTPM]":"68.7","Cell RNA - RPTEC TERT1 [nTPM]":"41.7","Cell RNA - RT4 [nTPM]":"2.9","Cell RNA - SCLC-21H [nTPM]":"27.9","Cell RNA - SH-SY5Y [nTPM]":"28.8","Cell RNA - SiHa [nTPM]":"319.5","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"38.3","Cell RNA - SuSa [nTPM]":"2.5","Cell RNA - T-47d [nTPM]":"0.4","Cell RNA - THP-1 [nTPM]":"27.4","Cell RNA - TIME [nTPM]":"28.3","Cell RNA - U-138 MG [nTPM]":"39.7","Cell RNA - U-2 OS [nTPM]":"51.9","Cell RNA - U-2197 [nTPM]":"68.6","Cell RNA - U-251 MG [nTPM]":"50.6","Cell RNA - U-266\/70 [nTPM]":"18.6","Cell RNA - U-266\/84 [nTPM]":"16.5","Cell RNA - U-698 [nTPM]":"3.6","Cell RNA - U-87 MG [nTPM]":"59.9","Cell RNA - U-937 [nTPM]":"90.9","Cell RNA - WM-115 [nTPM]":"30.9","Blood RNA - basophil [nTPM]":"1.4","Blood RNA - classical monocyte [nTPM]":"1.4","Blood RNA - eosinophil [nTPM]":"4.7","Blood RNA - gdT-cell [nTPM]":"11.6","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"13.8","Blood RNA - memory B-cell [nTPM]":"10.0","Blood RNA - memory CD4 T-cell [nTPM]":"11.5","Blood RNA - memory CD8 T-cell [nTPM]":"12.7","Blood RNA - myeloid DC [nTPM]":"6.3","Blood RNA - naive B-cell [nTPM]":"7.5","Blood RNA - naive CD4 T-cell [nTPM]":"13.6","Blood RNA - naive CD8 T-cell [nTPM]":"10.9","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"11.3","Blood RNA - non-classical monocyte [nTPM]":"2.5","Blood RNA - plasmacytoid DC [nTPM]":"2.4","Blood RNA - T-reg [nTPM]":"21.5","Blood RNA - total PBMC [nTPM]":"6.6","Brain RNA - amygdala [nTPM]":"30.4","Brain RNA - basal ganglia [nTPM]":"34.9","Brain RNA - cerebellum [nTPM]":"23.9","Brain RNA - cerebral cortex [nTPM]":"32.7","Brain RNA - hippocampal formation [nTPM]":"36.2","Brain RNA - hypothalamus [nTPM]":"27.1","Brain RNA - medulla oblongata [nTPM]":"19.5","Brain RNA - midbrain [nTPM]":"21.4","Brain RNA - pons [nTPM]":"20.0","Brain RNA - spinal cord [nTPM]":"19.3","Brain RNA - thalamus [nTPM]":"25.7","Brain RNA - white matter [nTPM]":"24.5","Single Cell Type RNA - Adipocytes [nTPM]":"8.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.2","Single Cell Type RNA - Astrocytes [nTPM]":"37.5","Single Cell Type RNA - B-cells [nTPM]":"19.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.6","Single Cell Type RNA - Bipolar cells [nTPM]":"14.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"243.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"14.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.0","Single Cell Type RNA - dendritic cells [nTPM]":"18.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"187.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.4","Single Cell Type RNA - Early spermatids [nTPM]":"19.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.8","Single Cell Type RNA - Endothelial cells [nTPM]":"9.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.2","Single Cell Type RNA - Erythroid cells [nTPM]":"23.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"71.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.9","Single Cell Type RNA - Fibroblasts [nTPM]":"21.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"31.2","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"8.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"38.2","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"84.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.6","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"7.0","Single Cell Type RNA - Late spermatids [nTPM]":"8.6","Single Cell Type RNA - Leydig cells [nTPM]":"6.2","Single Cell Type RNA - Macrophages [nTPM]":"5.2","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"26.2","Single Cell Type RNA - monocytes [nTPM]":"4.4","Single Cell Type RNA - Muller glia cells [nTPM]":"11.8","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"66.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"46.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.8","Single Cell Type RNA - Paneth cells [nTPM]":"5.3","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"31.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"27.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"24.6","Single Cell Type RNA - Spermatocytes [nTPM]":"35.6","Single Cell Type RNA - Spermatogonia [nTPM]":"19.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"27.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.8","Single Cell Type RNA - T-cells [nTPM]":"26.6","Single Cell Type RNA - Theca cells [nTPM]":"8.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.1","Single Cell Type RNA - Urothelial cells [nTPM]":"9.0"},{"Gene":"P3H1","Gene synonym":["GROS1","LEPRE1","LEPRECAN","MGC117314"],"Ensembl":"ENSG00000117385","Gene description":"Prolyl 3-hydroxylase 1","Uniprot":["Q32P28"],"Chromosome":"1","Position":"42746335-42767084","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Dioxygenase","Oxidoreductase"],"Disease involvement":["Dwarfism","Osteogenesis imperfecta"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"47.9","Extravillous trophoblasts":"56.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"fHDF\/TERT166":"193.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012113","HPA016980"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"18000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA012113":"AB_2668626","HPA016980":"AB_2669498"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.95e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-3"},"Tissue RNA - adipose tissue [nTPM]":"12.4","Tissue RNA - adrenal gland [nTPM]":"11.1","Tissue RNA - amygdala [nTPM]":"3.6","Tissue RNA - appendix [nTPM]":"8.7","Tissue RNA - basal ganglia [nTPM]":"3.5","Tissue RNA - bone marrow [nTPM]":"6.1","Tissue RNA - breast [nTPM]":"10.2","Tissue RNA - cerebellum [nTPM]":"3.6","Tissue RNA - cerebral cortex [nTPM]":"4.4","Tissue RNA - cervix [nTPM]":"13.4","Tissue RNA - choroid plexus [nTPM]":"7.3","Tissue RNA - colon [nTPM]":"8.3","Tissue RNA - duodenum [nTPM]":"2.4","Tissue RNA - endometrium 1 [nTPM]":"13.8","Tissue RNA - epididymis [nTPM]":"6.1","Tissue RNA - esophagus [nTPM]":"4.4","Tissue RNA - fallopian tube [nTPM]":"9.8","Tissue RNA - gallbladder [nTPM]":"12.0","Tissue RNA - heart muscle [nTPM]":"9.1","Tissue RNA - hippocampal formation [nTPM]":"3.8","Tissue RNA - hypothalamus [nTPM]":"3.8","Tissue RNA - kidney [nTPM]":"7.2","Tissue RNA - liver [nTPM]":"13.3","Tissue RNA - lung [nTPM]":"11.6","Tissue RNA - lymph node [nTPM]":"5.1","Tissue RNA - medulla oblongata [nTPM]":"5.2","Tissue RNA - midbrain [nTPM]":"3.5","Tissue RNA - ovary [nTPM]":"12.8","Tissue RNA - pancreas [nTPM]":"6.8","Tissue RNA - parathyroid gland [nTPM]":"5.9","Tissue RNA - pituitary gland [nTPM]":"15.5","Tissue RNA - placenta [nTPM]":"37.4","Tissue RNA - pons [nTPM]":"3.8","Tissue RNA - prostate [nTPM]":"7.5","Tissue RNA - rectum [nTPM]":"5.4","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"6.7","Tissue RNA - seminal vesicle [nTPM]":"5.9","Tissue RNA - skeletal muscle [nTPM]":"3.0","Tissue RNA - skin 1 [nTPM]":"7.6","Tissue RNA - small intestine [nTPM]":"7.4","Tissue RNA - smooth muscle [nTPM]":"20.3","Tissue RNA - spinal cord [nTPM]":"3.4","Tissue RNA - spleen [nTPM]":"11.5","Tissue RNA - stomach 1 [nTPM]":"6.7","Tissue RNA - testis [nTPM]":"15.2","Tissue RNA - thalamus [nTPM]":"3.8","Tissue RNA - thymus [nTPM]":"7.6","Tissue RNA - thyroid gland [nTPM]":"7.6","Tissue RNA - tongue [nTPM]":"3.9","Tissue RNA - tonsil [nTPM]":"5.1","Tissue RNA - urinary bladder [nTPM]":"12.3","Tissue RNA - vagina [nTPM]":"8.5","Tissue RNA - white matter [nTPM]":"3.6","Cell RNA - A-431 [nTPM]":"8.7","Cell RNA - A549 [nTPM]":"22.3","Cell RNA - AF22 [nTPM]":"48.7","Cell RNA - AN3-CA [nTPM]":"115.0","Cell RNA - ASC diff [nTPM]":"112.8","Cell RNA - ASC TERT1 [nTPM]":"85.4","Cell RNA - BEWO [nTPM]":"20.1","Cell RNA - BJ [nTPM]":"101.8","Cell RNA - BJ hTERT+ [nTPM]":"131.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"71.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"121.7","Cell RNA - CACO-2 [nTPM]":"11.3","Cell RNA - CAPAN-2 [nTPM]":"18.8","Cell RNA - Daudi [nTPM]":"13.0","Cell RNA - EFO-21 [nTPM]":"79.7","Cell RNA - fHDF\/TERT166 [nTPM]":"193.0","Cell RNA - GAMG [nTPM]":"29.2","Cell RNA - HaCaT [nTPM]":"7.8","Cell RNA - HAP1 [nTPM]":"20.9","Cell RNA - HBEC3-KT [nTPM]":"25.9","Cell RNA - HBF TERT88 [nTPM]":"49.2","Cell RNA - HDLM-2 [nTPM]":"19.5","Cell RNA - HEK 293 [nTPM]":"26.3","Cell RNA - HEL [nTPM]":"30.5","Cell RNA - HeLa [nTPM]":"32.2","Cell RNA - Hep G2 [nTPM]":"32.6","Cell RNA - HHSteC [nTPM]":"65.2","Cell RNA - HL-60 [nTPM]":"30.9","Cell RNA - HMC-1 [nTPM]":"34.0","Cell RNA - HSkMC [nTPM]":"73.8","Cell RNA - hTCEpi [nTPM]":"17.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"72.6","Cell RNA - hTERT-HME1 [nTPM]":"30.9","Cell RNA - hTERT-RPE1 [nTPM]":"102.4","Cell RNA - HUVEC TERT2 [nTPM]":"102.9","Cell RNA - JURKAT [nTPM]":"18.3","Cell RNA - K-562 [nTPM]":"17.5","Cell RNA - Karpas-707 [nTPM]":"16.1","Cell RNA - LHCN-M2 [nTPM]":"49.0","Cell RNA - MCF7 [nTPM]":"4.7","Cell RNA - MOLT-4 [nTPM]":"20.6","Cell RNA - NB-4 [nTPM]":"17.8","Cell RNA - NTERA-2 [nTPM]":"53.1","Cell RNA - OE19 [nTPM]":"4.7","Cell RNA - PC-3 [nTPM]":"16.0","Cell RNA - REH [nTPM]":"19.9","Cell RNA - RH-30 [nTPM]":"71.9","Cell RNA - RPMI-8226 [nTPM]":"17.7","Cell RNA - RPTEC TERT1 [nTPM]":"38.2","Cell RNA - RT4 [nTPM]":"4.9","Cell RNA - SCLC-21H [nTPM]":"10.2","Cell RNA - SH-SY5Y [nTPM]":"17.3","Cell RNA - SiHa [nTPM]":"62.5","Cell RNA - SK-BR-3 [nTPM]":"1.7","Cell RNA - SK-MEL-30 [nTPM]":"45.8","Cell RNA - SuSa [nTPM]":"85.2","Cell RNA - T-47d [nTPM]":"3.7","Cell RNA - THP-1 [nTPM]":"127.0","Cell RNA - TIME [nTPM]":"85.1","Cell RNA - U-138 MG [nTPM]":"53.8","Cell RNA - U-2 OS [nTPM]":"47.2","Cell RNA - U-2197 [nTPM]":"43.4","Cell RNA - U-251 MG [nTPM]":"41.2","Cell RNA - U-266\/70 [nTPM]":"14.5","Cell RNA - U-266\/84 [nTPM]":"17.5","Cell RNA - U-698 [nTPM]":"11.9","Cell RNA - U-87 MG [nTPM]":"61.5","Cell RNA - U-937 [nTPM]":"41.5","Cell RNA - WM-115 [nTPM]":"77.0","Blood RNA - basophil [nTPM]":"5.0","Blood RNA - classical monocyte [nTPM]":"18.9","Blood RNA - eosinophil [nTPM]":"16.8","Blood RNA - gdT-cell [nTPM]":"8.3","Blood RNA - intermediate monocyte [nTPM]":"20.4","Blood RNA - MAIT T-cell [nTPM]":"8.8","Blood RNA - memory B-cell [nTPM]":"4.1","Blood RNA - memory CD4 T-cell [nTPM]":"6.3","Blood RNA - memory CD8 T-cell [nTPM]":"7.0","Blood RNA - myeloid DC [nTPM]":"23.6","Blood RNA - naive B-cell [nTPM]":"3.3","Blood RNA - naive CD4 T-cell [nTPM]":"5.1","Blood RNA - naive CD8 T-cell [nTPM]":"5.3","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"17.8","Blood RNA - non-classical monocyte [nTPM]":"26.3","Blood RNA - plasmacytoid DC [nTPM]":"10.9","Blood RNA - T-reg [nTPM]":"12.4","Blood RNA - total PBMC [nTPM]":"9.3","Brain RNA - amygdala [nTPM]":"3.6","Brain RNA - basal ganglia [nTPM]":"3.5","Brain RNA - cerebellum [nTPM]":"3.6","Brain RNA - cerebral cortex [nTPM]":"4.4","Brain RNA - hippocampal formation [nTPM]":"3.8","Brain RNA - hypothalamus [nTPM]":"3.8","Brain RNA - medulla oblongata [nTPM]":"5.2","Brain RNA - midbrain [nTPM]":"3.5","Brain RNA - pons [nTPM]":"3.8","Brain RNA - spinal cord [nTPM]":"3.4","Brain RNA - thalamus [nTPM]":"3.8","Brain RNA - white matter [nTPM]":"3.6","Single Cell Type RNA - Adipocytes [nTPM]":"13.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.3","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"10.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"10.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"47.9","Single Cell Type RNA - dendritic cells [nTPM]":"11.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"11.5","Single Cell Type RNA - Early spermatids [nTPM]":"17.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"30.1","Single Cell Type RNA - Endothelial cells [nTPM]":"16.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.1","Single Cell Type RNA - Erythroid cells [nTPM]":"11.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"56.6","Single Cell Type RNA - Fibroblasts [nTPM]":"34.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.4","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"28.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.8","Single Cell Type RNA - Hepatocytes [nTPM]":"11.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.6","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"8.7","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"10.8","Single Cell Type RNA - Leydig cells [nTPM]":"19.3","Single Cell Type RNA - Macrophages [nTPM]":"11.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"10.5","Single Cell Type RNA - Muller glia cells [nTPM]":"3.5","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.4","Single Cell Type RNA - Paneth cells [nTPM]":"2.0","Single Cell Type RNA - Peritubular cells [nTPM]":"16.1","Single Cell Type RNA - Plasma cells [nTPM]":"11.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"22.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.3","Single Cell Type RNA - Spermatocytes [nTPM]":"30.6","Single Cell Type RNA - Spermatogonia [nTPM]":"18.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.5","Single Cell Type RNA - T-cells [nTPM]":"9.6","Single Cell Type RNA - Theca cells [nTPM]":"27.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.9","Single Cell Type RNA - Urothelial cells [nTPM]":"4.5"},{"Gene":"P3H2","Gene synonym":["FLJ10718","LEPREL1","MLAT4"],"Ensembl":"ENSG00000090530","Gene description":"Prolyl 3-hydroxylase 2","Uniprot":["Q8IVL5"],"Chromosome":"3","Position":"189956728-190122437","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Dioxygenase","Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"80.3","Granulosa cells":"124.1","Microglial cells":"91.8","Theca cells":"74.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"22","RNA blood cell specific nTPM":{"plasmacytoid DC":"28.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"90","RNA blood lineage specific nTPM":{"dendritic cells":"28.9"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"GAMG":"120.2","HaCaT":"109.9","RPTEC TERT1":"109.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007890","HPA013355","HPA013611"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Vesicles","Cytosol"],"Antibody RRID":{"HPA007890":"AB_1852796","HPA013355":"AB_1852798","HPA013611":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.9","Tissue RNA - adrenal gland [nTPM]":"41.6","Tissue RNA - amygdala [nTPM]":"2.8","Tissue RNA - appendix [nTPM]":"4.9","Tissue RNA - basal ganglia [nTPM]":"3.1","Tissue RNA - bone marrow [nTPM]":"1.0","Tissue RNA - breast [nTPM]":"6.5","Tissue RNA - cerebellum [nTPM]":"3.0","Tissue RNA - cerebral cortex [nTPM]":"3.1","Tissue RNA - cervix [nTPM]":"17.0","Tissue RNA - choroid plexus [nTPM]":"1.8","Tissue RNA - colon [nTPM]":"24.0","Tissue RNA - duodenum [nTPM]":"2.7","Tissue RNA - endometrium 1 [nTPM]":"17.6","Tissue RNA - epididymis [nTPM]":"18.5","Tissue RNA - esophagus [nTPM]":"11.0","Tissue RNA - fallopian tube [nTPM]":"8.0","Tissue RNA - gallbladder [nTPM]":"4.8","Tissue RNA - heart muscle [nTPM]":"8.8","Tissue RNA - hippocampal formation [nTPM]":"3.3","Tissue RNA - hypothalamus [nTPM]":"4.8","Tissue RNA - kidney [nTPM]":"51.3","Tissue RNA - liver [nTPM]":"7.0","Tissue RNA - lung [nTPM]":"28.7","Tissue RNA - lymph node [nTPM]":"2.4","Tissue RNA - medulla oblongata [nTPM]":"7.6","Tissue RNA - midbrain [nTPM]":"4.7","Tissue RNA - ovary [nTPM]":"16.1","Tissue RNA - pancreas [nTPM]":"3.6","Tissue RNA - parathyroid gland [nTPM]":"2.3","Tissue RNA - pituitary gland [nTPM]":"8.2","Tissue RNA - placenta [nTPM]":"9.2","Tissue RNA - pons [nTPM]":"6.7","Tissue RNA - prostate [nTPM]":"37.6","Tissue RNA - rectum [nTPM]":"10.4","Tissue RNA - retina [nTPM]":"19.3","Tissue RNA - salivary gland [nTPM]":"4.9","Tissue RNA - seminal vesicle [nTPM]":"26.5","Tissue RNA - skeletal muscle [nTPM]":"1.2","Tissue RNA - skin 1 [nTPM]":"17.8","Tissue RNA - small intestine [nTPM]":"6.7","Tissue RNA - smooth muscle [nTPM]":"32.4","Tissue RNA - spinal cord [nTPM]":"5.2","Tissue RNA - spleen [nTPM]":"54.8","Tissue RNA - stomach 1 [nTPM]":"23.9","Tissue RNA - testis [nTPM]":"4.2","Tissue RNA - thalamus [nTPM]":"4.9","Tissue RNA - thymus [nTPM]":"5.2","Tissue RNA - thyroid gland [nTPM]":"3.0","Tissue RNA - tongue [nTPM]":"1.7","Tissue RNA - tonsil [nTPM]":"2.0","Tissue RNA - urinary bladder [nTPM]":"11.9","Tissue RNA - vagina [nTPM]":"19.9","Tissue RNA - white matter [nTPM]":"8.3","Cell RNA - A-431 [nTPM]":"46.9","Cell RNA - A549 [nTPM]":"18.2","Cell RNA - AF22 [nTPM]":"35.1","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.6","Cell RNA - ASC TERT1 [nTPM]":"1.4","Cell RNA - BEWO [nTPM]":"42.1","Cell RNA - BJ [nTPM]":"48.7","Cell RNA - BJ hTERT+ [nTPM]":"19.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.6","Cell RNA - CACO-2 [nTPM]":"15.0","Cell RNA - CAPAN-2 [nTPM]":"18.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"27.1","Cell RNA - fHDF\/TERT166 [nTPM]":"8.6","Cell RNA - GAMG [nTPM]":"120.2","Cell RNA - HaCaT [nTPM]":"109.9","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"65.3","Cell RNA - HBF TERT88 [nTPM]":"16.3","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"6.2","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"12.1","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"35.4","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"16.9","Cell RNA - hTCEpi [nTPM]":"21.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.2","Cell RNA - hTERT-HME1 [nTPM]":"5.4","Cell RNA - hTERT-RPE1 [nTPM]":"73.5","Cell RNA - HUVEC TERT2 [nTPM]":"1.4","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"12.3","Cell RNA - MCF7 [nTPM]":"1.1","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"11.0","Cell RNA - OE19 [nTPM]":"31.3","Cell RNA - PC-3 [nTPM]":"3.7","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"7.1","Cell RNA - RPMI-8226 [nTPM]":"2.8","Cell RNA - RPTEC TERT1 [nTPM]":"109.8","Cell RNA - RT4 [nTPM]":"77.5","Cell RNA - SCLC-21H [nTPM]":"2.5","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"66.1","Cell RNA - SK-BR-3 [nTPM]":"3.7","Cell RNA - SK-MEL-30 [nTPM]":"29.3","Cell RNA - SuSa [nTPM]":"51.1","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.7","Cell RNA - TIME [nTPM]":"24.4","Cell RNA - U-138 MG [nTPM]":"45.9","Cell RNA - U-2 OS [nTPM]":"16.8","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"8.9","Cell RNA - U-266\/70 [nTPM]":"3.4","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"10.6","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"60.2","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"1.2","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"28.9","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"2.8","Brain RNA - basal ganglia [nTPM]":"3.1","Brain RNA - cerebellum [nTPM]":"3.0","Brain RNA - cerebral cortex [nTPM]":"3.1","Brain RNA - hippocampal formation [nTPM]":"3.3","Brain RNA - hypothalamus [nTPM]":"4.8","Brain RNA - medulla oblongata [nTPM]":"7.6","Brain RNA - midbrain [nTPM]":"4.7","Brain RNA - pons [nTPM]":"6.7","Brain RNA - spinal cord [nTPM]":"5.2","Brain RNA - thalamus [nTPM]":"4.9","Brain RNA - white matter [nTPM]":"8.3","Single Cell Type RNA - Adipocytes [nTPM]":"5.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"80.3","Single Cell Type RNA - Astrocytes [nTPM]":"19.2","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"2.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"3.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"42.0","Single Cell Type RNA - dendritic cells [nTPM]":"9.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"19.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.7","Single Cell Type RNA - Early spermatids [nTPM]":"19.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"27.3","Single Cell Type RNA - Endothelial cells [nTPM]":"10.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"55.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.7","Single Cell Type RNA - Fibroblasts [nTPM]":"10.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"124.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.5","Single Cell Type RNA - Hepatocytes [nTPM]":"0.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.4","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"60.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.2","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"14.9","Single Cell Type RNA - Leydig cells [nTPM]":"4.7","Single Cell Type RNA - Macrophages [nTPM]":"5.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"91.8","Single Cell Type RNA - monocytes [nTPM]":"0.8","Single Cell Type RNA - Muller glia cells [nTPM]":"44.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"43.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"30.6","Single Cell Type RNA - Paneth cells [nTPM]":"1.9","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"26.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"45.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"38.6","Single Cell Type RNA - T-cells [nTPM]":"0.7","Single Cell Type RNA - Theca cells [nTPM]":"74.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.1","Single Cell Type RNA - Urothelial cells [nTPM]":"3.9"},{"Gene":"P4HA2","Gene synonym":["C-P4Halpha(II)"],"Ensembl":"ENSG00000072682","Gene description":"Prolyl 4-hydroxylase subunit alpha 2","Uniprot":["O15460"],"Chromosome":"5","Position":"132190147-132295315","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Dioxygenase","Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"115.6","Endometrial stromal cells":"96.9","Skeletal myocytes":"109.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HHSteC":"324.2","U-87 MG":"323.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016997","HPA027824","CAB062557"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"13000","Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Endoplasmic reticulum","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB062557":"AB_2665641","HPA016997":"AB_2669501","HPA027824":"AB_2672402"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.24e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.77e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.12e-4"},"Tissue RNA - adipose tissue [nTPM]":"17.4","Tissue RNA - adrenal gland [nTPM]":"11.7","Tissue RNA - amygdala [nTPM]":"11.9","Tissue RNA - appendix [nTPM]":"16.1","Tissue RNA - basal ganglia [nTPM]":"12.1","Tissue RNA - bone marrow [nTPM]":"2.4","Tissue RNA - breast [nTPM]":"12.3","Tissue RNA - cerebellum [nTPM]":"11.4","Tissue RNA - cerebral cortex [nTPM]":"28.4","Tissue RNA - cervix [nTPM]":"29.5","Tissue RNA - choroid plexus [nTPM]":"42.2","Tissue RNA - colon [nTPM]":"28.7","Tissue RNA - duodenum [nTPM]":"22.6","Tissue RNA - endometrium 1 [nTPM]":"31.1","Tissue RNA - epididymis [nTPM]":"76.7","Tissue RNA - esophagus [nTPM]":"19.6","Tissue RNA - fallopian tube [nTPM]":"29.6","Tissue RNA - gallbladder [nTPM]":"19.9","Tissue RNA - heart muscle [nTPM]":"40.6","Tissue RNA - hippocampal formation [nTPM]":"14.4","Tissue RNA - hypothalamus [nTPM]":"17.2","Tissue RNA - kidney [nTPM]":"80.0","Tissue RNA - liver [nTPM]":"10.5","Tissue RNA - lung [nTPM]":"31.5","Tissue RNA - lymph node [nTPM]":"2.5","Tissue RNA - medulla oblongata [nTPM]":"11.4","Tissue RNA - midbrain [nTPM]":"14.3","Tissue RNA - ovary [nTPM]":"8.6","Tissue RNA - pancreas [nTPM]":"70.7","Tissue RNA - parathyroid gland [nTPM]":"10.9","Tissue RNA - pituitary gland [nTPM]":"19.9","Tissue RNA - placenta [nTPM]":"35.1","Tissue RNA - pons [nTPM]":"19.1","Tissue RNA - prostate [nTPM]":"10.8","Tissue RNA - rectum [nTPM]":"32.7","Tissue RNA - retina [nTPM]":"7.8","Tissue RNA - salivary gland [nTPM]":"32.5","Tissue RNA - seminal vesicle [nTPM]":"17.1","Tissue RNA - skeletal muscle [nTPM]":"13.0","Tissue RNA - skin 1 [nTPM]":"16.7","Tissue RNA - small intestine [nTPM]":"26.8","Tissue RNA - smooth muscle [nTPM]":"52.6","Tissue RNA - spinal cord [nTPM]":"10.0","Tissue RNA - spleen [nTPM]":"8.7","Tissue RNA - stomach 1 [nTPM]":"20.5","Tissue RNA - testis [nTPM]":"9.7","Tissue RNA - thalamus [nTPM]":"16.8","Tissue RNA - thymus [nTPM]":"11.3","Tissue RNA - thyroid gland [nTPM]":"20.7","Tissue RNA - tongue [nTPM]":"22.9","Tissue RNA - tonsil [nTPM]":"8.3","Tissue RNA - urinary bladder [nTPM]":"22.9","Tissue RNA - vagina [nTPM]":"22.3","Tissue RNA - white matter [nTPM]":"12.2","Cell RNA - A-431 [nTPM]":"57.0","Cell RNA - A549 [nTPM]":"34.9","Cell RNA - AF22 [nTPM]":"11.2","Cell RNA - AN3-CA [nTPM]":"57.2","Cell RNA - ASC diff [nTPM]":"149.2","Cell RNA - ASC TERT1 [nTPM]":"173.7","Cell RNA - BEWO [nTPM]":"61.1","Cell RNA - BJ [nTPM]":"261.9","Cell RNA - BJ hTERT+ [nTPM]":"223.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"108.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"265.0","Cell RNA - CACO-2 [nTPM]":"78.9","Cell RNA - CAPAN-2 [nTPM]":"50.3","Cell RNA - Daudi [nTPM]":"1.5","Cell RNA - EFO-21 [nTPM]":"71.8","Cell RNA - fHDF\/TERT166 [nTPM]":"283.3","Cell RNA - GAMG [nTPM]":"120.5","Cell RNA - HaCaT [nTPM]":"70.2","Cell RNA - HAP1 [nTPM]":"33.2","Cell RNA - HBEC3-KT [nTPM]":"136.5","Cell RNA - HBF TERT88 [nTPM]":"172.7","Cell RNA - HDLM-2 [nTPM]":"41.5","Cell RNA - HEK 293 [nTPM]":"11.9","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"48.1","Cell RNA - Hep G2 [nTPM]":"49.0","Cell RNA - HHSteC [nTPM]":"324.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"33.9","Cell RNA - HSkMC [nTPM]":"104.6","Cell RNA - hTCEpi [nTPM]":"193.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"128.8","Cell RNA - hTERT-HME1 [nTPM]":"117.4","Cell RNA - hTERT-RPE1 [nTPM]":"162.7","Cell RNA - HUVEC TERT2 [nTPM]":"59.1","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"21.2","Cell RNA - Karpas-707 [nTPM]":"3.6","Cell RNA - LHCN-M2 [nTPM]":"134.0","Cell RNA - MCF7 [nTPM]":"23.2","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"3.0","Cell RNA - OE19 [nTPM]":"53.7","Cell RNA - PC-3 [nTPM]":"27.2","Cell RNA - REH [nTPM]":"0.9","Cell RNA - RH-30 [nTPM]":"3.6","Cell RNA - RPMI-8226 [nTPM]":"9.8","Cell RNA - RPTEC TERT1 [nTPM]":"31.1","Cell RNA - RT4 [nTPM]":"11.0","Cell RNA - SCLC-21H [nTPM]":"5.4","Cell RNA - SH-SY5Y [nTPM]":"15.8","Cell RNA - SiHa [nTPM]":"67.7","Cell RNA - SK-BR-3 [nTPM]":"22.3","Cell RNA - SK-MEL-30 [nTPM]":"47.9","Cell RNA - SuSa [nTPM]":"84.1","Cell RNA - T-47d [nTPM]":"28.4","Cell RNA - THP-1 [nTPM]":"3.7","Cell RNA - TIME [nTPM]":"88.9","Cell RNA - U-138 MG [nTPM]":"171.7","Cell RNA - U-2 OS [nTPM]":"63.5","Cell RNA - U-2197 [nTPM]":"51.0","Cell RNA - U-251 MG [nTPM]":"57.1","Cell RNA - U-266\/70 [nTPM]":"24.4","Cell RNA - U-266\/84 [nTPM]":"28.1","Cell RNA - U-698 [nTPM]":"11.8","Cell RNA - U-87 MG [nTPM]":"323.4","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"48.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"0.9","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"11.9","Brain RNA - basal ganglia [nTPM]":"12.1","Brain RNA - cerebellum [nTPM]":"11.4","Brain RNA - cerebral cortex [nTPM]":"28.4","Brain RNA - hippocampal formation [nTPM]":"14.4","Brain RNA - hypothalamus [nTPM]":"17.2","Brain RNA - medulla oblongata [nTPM]":"11.4","Brain RNA - midbrain [nTPM]":"14.3","Brain RNA - pons [nTPM]":"19.1","Brain RNA - spinal cord [nTPM]":"10.0","Brain RNA - thalamus [nTPM]":"16.8","Brain RNA - white matter [nTPM]":"12.2","Single Cell Type RNA - Adipocytes [nTPM]":"13.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.3","Single Cell Type RNA - Astrocytes [nTPM]":"7.5","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"43.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"115.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.9","Single Cell Type RNA - Bipolar cells [nTPM]":"11.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"36.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"43.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"68.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"26.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"96.9","Single Cell Type RNA - Endothelial cells [nTPM]":"12.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"71.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"70.2","Single Cell Type RNA - Fibroblasts [nTPM]":"61.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"28.0","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"11.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.3","Single Cell Type RNA - Hepatocytes [nTPM]":"7.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.6","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"5.5","Single Cell Type RNA - Late spermatids [nTPM]":"2.0","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"4.4","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"2.6","Single Cell Type RNA - Muller glia cells [nTPM]":"6.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"81.9","Single Cell Type RNA - Paneth cells [nTPM]":"41.0","Single Cell Type RNA - Peritubular cells [nTPM]":"5.3","Single Cell Type RNA - Plasma cells [nTPM]":"3.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"41.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"44.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"71.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.2","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"109.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"47.6","Single Cell Type RNA - Spermatocytes [nTPM]":"23.0","Single Cell Type RNA - Spermatogonia [nTPM]":"29.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.5","Single Cell Type RNA - T-cells [nTPM]":"4.8","Single Cell Type RNA - Theca cells [nTPM]":"10.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.8","Single Cell Type RNA - Urothelial cells [nTPM]":"15.3"},{"Gene":"P4HB","Gene synonym":["DSI","ERBA2L","GIT","P4Hbeta","PDI","PDIA1","PO4DB","PO4HB","PROHB"],"Ensembl":"ENSG00000185624","Gene description":"Prolyl 4-hydroxylase subunit beta","Uniprot":["P07237"],"Chromosome":"17","Position":"81843159-81860856","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Chaperone","Isomerase"],"Disease involvement":["Craniosynostosis","Disease variant","Osteogenesis imperfecta"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"1856.8","pancreas":"2446.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Exocrine glandular cells":"1077.9","Extravillous trophoblasts":"1349.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB012463","HPA018884"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":"Intracellular and membrane","CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB012463":null,"HPA018884":"AB_1854896"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.47e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.30e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-3"},"Tissue RNA - adipose tissue [nTPM]":"266.5","Tissue RNA - adrenal gland [nTPM]":"507.8","Tissue RNA - amygdala [nTPM]":"34.6","Tissue RNA - appendix [nTPM]":"209.8","Tissue RNA - basal ganglia [nTPM]":"35.7","Tissue RNA - bone marrow [nTPM]":"517.1","Tissue RNA - breast [nTPM]":"225.5","Tissue RNA - cerebellum [nTPM]":"39.1","Tissue RNA - cerebral cortex [nTPM]":"35.7","Tissue RNA - cervix [nTPM]":"272.0","Tissue RNA - choroid plexus [nTPM]":"59.6","Tissue RNA - colon [nTPM]":"258.4","Tissue RNA - duodenum [nTPM]":"640.2","Tissue RNA - endometrium 1 [nTPM]":"206.5","Tissue RNA - epididymis [nTPM]":"133.0","Tissue RNA - esophagus [nTPM]":"618.7","Tissue RNA - fallopian tube [nTPM]":"183.4","Tissue RNA - gallbladder [nTPM]":"202.0","Tissue RNA - heart muscle [nTPM]":"318.4","Tissue RNA - hippocampal formation [nTPM]":"31.7","Tissue RNA - hypothalamus [nTPM]":"50.2","Tissue RNA - kidney [nTPM]":"270.7","Tissue RNA - liver [nTPM]":"1856.8","Tissue RNA - lung [nTPM]":"301.3","Tissue RNA - lymph node [nTPM]":"104.0","Tissue RNA - medulla oblongata [nTPM]":"48.9","Tissue RNA - midbrain [nTPM]":"37.1","Tissue RNA - ovary [nTPM]":"187.8","Tissue RNA - pancreas [nTPM]":"2446.9","Tissue RNA - parathyroid gland [nTPM]":"144.3","Tissue RNA - pituitary gland [nTPM]":"330.0","Tissue RNA - placenta [nTPM]":"334.3","Tissue RNA - pons [nTPM]":"40.8","Tissue RNA - prostate [nTPM]":"335.8","Tissue RNA - rectum [nTPM]":"173.6","Tissue RNA - retina [nTPM]":"23.3","Tissue RNA - salivary gland [nTPM]":"948.1","Tissue RNA - seminal vesicle [nTPM]":"184.2","Tissue RNA - skeletal muscle [nTPM]":"328.5","Tissue RNA - skin 1 [nTPM]":"370.4","Tissue RNA - small intestine [nTPM]":"554.7","Tissue RNA - smooth muscle [nTPM]":"179.8","Tissue RNA - spinal cord [nTPM]":"39.8","Tissue RNA - spleen [nTPM]":"428.6","Tissue RNA - stomach 1 [nTPM]":"539.2","Tissue RNA - testis [nTPM]":"68.8","Tissue RNA - thalamus [nTPM]":"58.7","Tissue RNA - thymus [nTPM]":"89.3","Tissue RNA - thyroid gland [nTPM]":"244.8","Tissue RNA - tongue [nTPM]":"150.8","Tissue RNA - tonsil [nTPM]":"137.9","Tissue RNA - urinary bladder [nTPM]":"233.7","Tissue RNA - vagina [nTPM]":"322.9","Tissue RNA - white matter [nTPM]":"43.7","Cell RNA - A-431 [nTPM]":"690.3","Cell RNA - A549 [nTPM]":"580.7","Cell RNA - AF22 [nTPM]":"236.8","Cell RNA - AN3-CA [nTPM]":"687.5","Cell RNA - ASC diff [nTPM]":"813.4","Cell RNA - ASC TERT1 [nTPM]":"726.7","Cell RNA - BEWO [nTPM]":"593.6","Cell RNA - BJ [nTPM]":"1038.5","Cell RNA - BJ hTERT+ [nTPM]":"1081.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"741.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"934.5","Cell RNA - CACO-2 [nTPM]":"550.4","Cell RNA - CAPAN-2 [nTPM]":"576.9","Cell RNA - Daudi [nTPM]":"264.4","Cell RNA - EFO-21 [nTPM]":"501.8","Cell RNA - fHDF\/TERT166 [nTPM]":"1120.2","Cell RNA - GAMG [nTPM]":"407.5","Cell RNA - HaCaT [nTPM]":"464.1","Cell RNA - HAP1 [nTPM]":"248.8","Cell RNA - HBEC3-KT [nTPM]":"647.4","Cell RNA - HBF TERT88 [nTPM]":"254.1","Cell RNA - HDLM-2 [nTPM]":"145.8","Cell RNA - HEK 293 [nTPM]":"320.5","Cell RNA - HEL [nTPM]":"355.2","Cell RNA - HeLa [nTPM]":"362.9","Cell RNA - Hep G2 [nTPM]":"953.6","Cell RNA - HHSteC [nTPM]":"1010.8","Cell RNA - HL-60 [nTPM]":"1146.4","Cell RNA - HMC-1 [nTPM]":"613.4","Cell RNA - HSkMC [nTPM]":"618.8","Cell RNA - hTCEpi [nTPM]":"494.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"478.2","Cell RNA - hTERT-HME1 [nTPM]":"596.7","Cell RNA - hTERT-RPE1 [nTPM]":"843.0","Cell RNA - HUVEC TERT2 [nTPM]":"1250.1","Cell RNA - JURKAT [nTPM]":"182.1","Cell RNA - K-562 [nTPM]":"273.6","Cell RNA - Karpas-707 [nTPM]":"978.2","Cell RNA - LHCN-M2 [nTPM]":"559.5","Cell RNA - MCF7 [nTPM]":"566.4","Cell RNA - MOLT-4 [nTPM]":"260.5","Cell RNA - NB-4 [nTPM]":"723.2","Cell RNA - NTERA-2 [nTPM]":"157.7","Cell RNA - OE19 [nTPM]":"791.0","Cell RNA - PC-3 [nTPM]":"463.8","Cell RNA - REH [nTPM]":"261.8","Cell RNA - RH-30 [nTPM]":"342.5","Cell RNA - RPMI-8226 [nTPM]":"614.0","Cell RNA - RPTEC TERT1 [nTPM]":"453.2","Cell RNA - RT4 [nTPM]":"492.8","Cell RNA - SCLC-21H [nTPM]":"248.7","Cell RNA - SH-SY5Y [nTPM]":"301.1","Cell RNA - SiHa [nTPM]":"586.1","Cell RNA - SK-BR-3 [nTPM]":"1693.1","Cell RNA - SK-MEL-30 [nTPM]":"808.1","Cell RNA - SuSa [nTPM]":"289.6","Cell RNA - T-47d [nTPM]":"855.3","Cell RNA - THP-1 [nTPM]":"1601.2","Cell RNA - TIME [nTPM]":"644.1","Cell RNA - U-138 MG [nTPM]":"980.5","Cell RNA - U-2 OS [nTPM]":"503.1","Cell RNA - U-2197 [nTPM]":"574.3","Cell RNA - U-251 MG [nTPM]":"586.6","Cell RNA - U-266\/70 [nTPM]":"743.5","Cell RNA - U-266\/84 [nTPM]":"407.9","Cell RNA - U-698 [nTPM]":"204.8","Cell RNA - U-87 MG [nTPM]":"1372.0","Cell RNA - U-937 [nTPM]":"591.3","Cell RNA - WM-115 [nTPM]":"825.4","Blood RNA - basophil [nTPM]":"198.3","Blood RNA - classical monocyte [nTPM]":"268.1","Blood RNA - eosinophil [nTPM]":"163.0","Blood RNA - gdT-cell [nTPM]":"202.6","Blood RNA - intermediate monocyte [nTPM]":"154.4","Blood RNA - MAIT T-cell [nTPM]":"209.8","Blood RNA - memory B-cell [nTPM]":"83.9","Blood RNA - memory CD4 T-cell [nTPM]":"138.9","Blood RNA - memory CD8 T-cell [nTPM]":"165.7","Blood RNA - myeloid DC [nTPM]":"174.7","Blood RNA - naive B-cell [nTPM]":"68.1","Blood RNA - naive CD4 T-cell [nTPM]":"74.9","Blood RNA - naive CD8 T-cell [nTPM]":"114.6","Blood RNA - neutrophil [nTPM]":"72.9","Blood RNA - NK-cell [nTPM]":"157.0","Blood RNA - non-classical monocyte [nTPM]":"115.3","Blood RNA - plasmacytoid DC [nTPM]":"311.5","Blood RNA - T-reg [nTPM]":"105.6","Blood RNA - total PBMC [nTPM]":"372.4","Brain RNA - amygdala [nTPM]":"34.6","Brain RNA - basal ganglia [nTPM]":"35.7","Brain RNA - cerebellum [nTPM]":"39.1","Brain RNA - cerebral cortex [nTPM]":"35.7","Brain RNA - hippocampal formation [nTPM]":"31.7","Brain RNA - hypothalamus [nTPM]":"50.2","Brain RNA - medulla oblongata [nTPM]":"48.9","Brain RNA - midbrain [nTPM]":"37.1","Brain RNA - pons [nTPM]":"40.8","Brain RNA - spinal cord [nTPM]":"39.8","Brain RNA - thalamus [nTPM]":"58.7","Brain RNA - white matter [nTPM]":"43.7","Single Cell Type RNA - Adipocytes [nTPM]":"122.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"102.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"162.1","Single Cell Type RNA - Astrocytes [nTPM]":"23.2","Single Cell Type RNA - B-cells [nTPM]":"151.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"120.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"163.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"371.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"140.6","Single Cell Type RNA - Bipolar cells [nTPM]":"59.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"283.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"170.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"24.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"247.4","Single Cell Type RNA - Club cells [nTPM]":"211.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"112.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"790.2","Single Cell Type RNA - dendritic cells [nTPM]":"208.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"420.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"41.1","Single Cell Type RNA - Ductal cells [nTPM]":"671.9","Single Cell Type RNA - Early spermatids [nTPM]":"43.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"78.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"196.8","Single Cell Type RNA - Endothelial cells [nTPM]":"153.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"199.9","Single Cell Type RNA - Erythroid cells [nTPM]":"140.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1077.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1349.1","Single Cell Type RNA - Fibroblasts [nTPM]":"272.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"388.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"209.1","Single Cell Type RNA - granulocytes [nTPM]":"99.1","Single Cell Type RNA - Granulosa cells [nTPM]":"210.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"190.2","Single Cell Type RNA - Hepatocytes [nTPM]":"840.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"435.9","Single Cell Type RNA - Horizontal cells [nTPM]":"62.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"16.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"610.9","Single Cell Type RNA - Ionocytes [nTPM]":"189.2","Single Cell Type RNA - Kupffer cells [nTPM]":"186.9","Single Cell Type RNA - Langerhans cells [nTPM]":"125.5","Single Cell Type RNA - Late spermatids [nTPM]":"64.9","Single Cell Type RNA - Leydig cells [nTPM]":"141.4","Single Cell Type RNA - Macrophages [nTPM]":"180.3","Single Cell Type RNA - Melanocytes [nTPM]":"136.9","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"263.3","Single Cell Type RNA - Muller glia cells [nTPM]":"122.7","Single Cell Type RNA - NK-cells [nTPM]":"230.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"575.2","Single Cell Type RNA - Paneth cells [nTPM]":"465.6","Single Cell Type RNA - Peritubular cells [nTPM]":"112.1","Single Cell Type RNA - Plasma cells [nTPM]":"664.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"310.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"914.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"105.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"91.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"54.3","Single Cell Type RNA - Sertoli cells [nTPM]":"157.8","Single Cell Type RNA - Skeletal myocytes [nTPM]":"103.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"226.7","Single Cell Type RNA - Spermatocytes [nTPM]":"83.4","Single Cell Type RNA - Spermatogonia [nTPM]":"94.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"302.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"144.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1001.2","Single Cell Type RNA - T-cells [nTPM]":"138.8","Single Cell Type RNA - Theca cells [nTPM]":"378.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"475.4","Single Cell Type RNA - Urothelial cells [nTPM]":"220.8"},{"Gene":"P4HTM","Gene synonym":["EGLN4","FLJ20262","HIFPH4","P4H-TM","PH-4","PH4","PHD4"],"Ensembl":"ENSG00000178467","Gene description":"Prolyl 4-hydroxylase, transmembrane","Uniprot":["Q9NXG6"],"Chromosome":"3","Position":"48989889-49007153","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Dioxygenase","Oxidoreductase"],"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"155.3","Respiratory ciliated cells":"169.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007199"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA007199":"AB_1855272"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.18e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.28e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.65e-3"},"Tissue RNA - adipose tissue [nTPM]":"13.3","Tissue RNA - adrenal gland [nTPM]":"37.1","Tissue RNA - amygdala [nTPM]":"50.6","Tissue RNA - appendix [nTPM]":"4.9","Tissue RNA - basal ganglia [nTPM]":"53.3","Tissue RNA - bone marrow [nTPM]":"5.9","Tissue RNA - breast [nTPM]":"12.4","Tissue RNA - cerebellum [nTPM]":"44.3","Tissue RNA - cerebral cortex [nTPM]":"67.9","Tissue RNA - cervix [nTPM]":"18.4","Tissue RNA - choroid plexus [nTPM]":"89.7","Tissue RNA - colon [nTPM]":"14.7","Tissue RNA - duodenum [nTPM]":"12.1","Tissue RNA - endometrium 1 [nTPM]":"17.6","Tissue RNA - epididymis [nTPM]":"18.7","Tissue RNA - esophagus [nTPM]":"8.2","Tissue RNA - fallopian tube [nTPM]":"39.8","Tissue RNA - gallbladder [nTPM]":"11.2","Tissue RNA - heart muscle [nTPM]":"26.2","Tissue RNA - hippocampal formation [nTPM]":"53.5","Tissue RNA - hypothalamus [nTPM]":"57.3","Tissue RNA - kidney [nTPM]":"29.8","Tissue RNA - liver [nTPM]":"11.9","Tissue RNA - lung [nTPM]":"15.7","Tissue RNA - lymph node [nTPM]":"6.5","Tissue RNA - medulla oblongata [nTPM]":"52.2","Tissue RNA - midbrain [nTPM]":"49.6","Tissue RNA - ovary [nTPM]":"20.0","Tissue RNA - pancreas [nTPM]":"38.5","Tissue RNA - parathyroid gland [nTPM]":"39.4","Tissue RNA - pituitary gland [nTPM]":"75.9","Tissue RNA - placenta [nTPM]":"11.0","Tissue RNA - pons [nTPM]":"51.5","Tissue RNA - prostate [nTPM]":"18.5","Tissue RNA - rectum [nTPM]":"7.4","Tissue RNA - retina [nTPM]":"16.4","Tissue RNA - salivary gland [nTPM]":"19.6","Tissue RNA - seminal vesicle [nTPM]":"16.8","Tissue RNA - skeletal muscle [nTPM]":"15.2","Tissue RNA - skin 1 [nTPM]":"10.1","Tissue RNA - small intestine [nTPM]":"13.0","Tissue RNA - smooth muscle [nTPM]":"7.4","Tissue RNA - spinal cord [nTPM]":"45.8","Tissue RNA - spleen [nTPM]":"10.7","Tissue RNA - stomach 1 [nTPM]":"25.1","Tissue RNA - testis [nTPM]":"23.6","Tissue RNA - thalamus [nTPM]":"53.3","Tissue RNA - thymus [nTPM]":"5.5","Tissue RNA - thyroid gland [nTPM]":"26.5","Tissue RNA - tongue [nTPM]":"11.3","Tissue RNA - tonsil [nTPM]":"3.8","Tissue RNA - urinary bladder [nTPM]":"12.8","Tissue RNA - vagina [nTPM]":"13.1","Tissue RNA - white matter [nTPM]":"49.6","Cell RNA - A-431 [nTPM]":"8.6","Cell RNA - A549 [nTPM]":"27.9","Cell RNA - AF22 [nTPM]":"4.8","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"15.5","Cell RNA - ASC TERT1 [nTPM]":"17.6","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"16.8","Cell RNA - BJ hTERT+ [nTPM]":"24.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.8","Cell RNA - CACO-2 [nTPM]":"6.3","Cell RNA - CAPAN-2 [nTPM]":"55.6","Cell RNA - Daudi [nTPM]":"8.1","Cell RNA - EFO-21 [nTPM]":"15.8","Cell RNA - fHDF\/TERT166 [nTPM]":"21.6","Cell RNA - GAMG [nTPM]":"10.5","Cell RNA - HaCaT [nTPM]":"4.8","Cell RNA - HAP1 [nTPM]":"12.5","Cell RNA - HBEC3-KT [nTPM]":"6.6","Cell RNA - HBF TERT88 [nTPM]":"4.1","Cell RNA - HDLM-2 [nTPM]":"30.4","Cell RNA - HEK 293 [nTPM]":"19.5","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"42.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"38.6","Cell RNA - HL-60 [nTPM]":"8.3","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"11.0","Cell RNA - hTCEpi [nTPM]":"6.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.4","Cell RNA - hTERT-HME1 [nTPM]":"1.1","Cell RNA - hTERT-RPE1 [nTPM]":"51.4","Cell RNA - HUVEC TERT2 [nTPM]":"15.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"37.9","Cell RNA - LHCN-M2 [nTPM]":"6.5","Cell RNA - MCF7 [nTPM]":"48.1","Cell RNA - MOLT-4 [nTPM]":"1.2","Cell RNA - NB-4 [nTPM]":"1.0","Cell RNA - NTERA-2 [nTPM]":"6.8","Cell RNA - OE19 [nTPM]":"52.6","Cell RNA - PC-3 [nTPM]":"31.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"53.5","Cell RNA - RPTEC TERT1 [nTPM]":"24.4","Cell RNA - RT4 [nTPM]":"15.9","Cell RNA - SCLC-21H [nTPM]":"20.9","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"17.7","Cell RNA - SK-BR-3 [nTPM]":"25.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"1.1","Cell RNA - T-47d [nTPM]":"20.1","Cell RNA - THP-1 [nTPM]":"13.1","Cell RNA - TIME [nTPM]":"9.9","Cell RNA - U-138 MG [nTPM]":"8.0","Cell RNA - U-2 OS [nTPM]":"6.1","Cell RNA - U-2197 [nTPM]":"19.9","Cell RNA - U-251 MG [nTPM]":"14.5","Cell RNA - U-266\/70 [nTPM]":"50.0","Cell RNA - U-266\/84 [nTPM]":"28.6","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"54.9","Cell RNA - U-937 [nTPM]":"0.7","Cell RNA - WM-115 [nTPM]":"7.1","Blood RNA - basophil [nTPM]":"8.0","Blood RNA - classical monocyte [nTPM]":"9.0","Blood RNA - eosinophil [nTPM]":"5.9","Blood RNA - gdT-cell [nTPM]":"6.7","Blood RNA - intermediate monocyte [nTPM]":"3.5","Blood RNA - MAIT T-cell [nTPM]":"9.6","Blood RNA - memory B-cell [nTPM]":"8.4","Blood RNA - memory CD4 T-cell [nTPM]":"12.3","Blood RNA - memory CD8 T-cell [nTPM]":"11.7","Blood RNA - myeloid DC [nTPM]":"9.4","Blood RNA - naive B-cell [nTPM]":"15.9","Blood RNA - naive CD4 T-cell [nTPM]":"13.0","Blood RNA - naive CD8 T-cell [nTPM]":"8.3","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"5.9","Blood RNA - non-classical monocyte [nTPM]":"4.5","Blood RNA - plasmacytoid DC [nTPM]":"1.6","Blood RNA - T-reg [nTPM]":"17.0","Blood RNA - total PBMC [nTPM]":"6.0","Brain RNA - amygdala [nTPM]":"50.6","Brain RNA - basal ganglia [nTPM]":"53.3","Brain RNA - cerebellum [nTPM]":"44.3","Brain RNA - cerebral cortex [nTPM]":"67.9","Brain RNA - hippocampal formation [nTPM]":"53.5","Brain RNA - hypothalamus [nTPM]":"57.3","Brain RNA - medulla oblongata [nTPM]":"52.2","Brain RNA - midbrain [nTPM]":"49.6","Brain RNA - pons [nTPM]":"51.5","Brain RNA - spinal cord [nTPM]":"45.8","Brain RNA - thalamus [nTPM]":"53.3","Brain RNA - white matter [nTPM]":"49.6","Single Cell Type RNA - Adipocytes [nTPM]":"15.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.3","Single Cell Type RNA - Astrocytes [nTPM]":"36.2","Single Cell Type RNA - B-cells [nTPM]":"16.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"34.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"41.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Bipolar cells [nTPM]":"72.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"28.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"41.5","Single Cell Type RNA - Club cells [nTPM]":"44.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"46.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"87.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"31.4","Single Cell Type RNA - dendritic cells [nTPM]":"13.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"27.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"38.3","Single Cell Type RNA - Early spermatids [nTPM]":"138.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"106.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.7","Single Cell Type RNA - Endothelial cells [nTPM]":"12.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"80.9","Single Cell Type RNA - Erythroid cells [nTPM]":"12.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"55.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"39.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.9","Single Cell Type RNA - Fibroblasts [nTPM]":"28.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"48.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"31.2","Single Cell Type RNA - granulocytes [nTPM]":"22.9","Single Cell Type RNA - Granulosa cells [nTPM]":"31.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.4","Single Cell Type RNA - Hepatocytes [nTPM]":"8.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.8","Single Cell Type RNA - Horizontal cells [nTPM]":"117.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"48.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"40.4","Single Cell Type RNA - Ionocytes [nTPM]":"65.1","Single Cell Type RNA - Kupffer cells [nTPM]":"6.3","Single Cell Type RNA - Langerhans cells [nTPM]":"12.8","Single Cell Type RNA - Late spermatids [nTPM]":"155.3","Single Cell Type RNA - Leydig cells [nTPM]":"30.4","Single Cell Type RNA - Macrophages [nTPM]":"13.0","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"11.3","Single Cell Type RNA - Muller glia cells [nTPM]":"58.4","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"32.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"23.6","Single Cell Type RNA - Paneth cells [nTPM]":"51.8","Single Cell Type RNA - Peritubular cells [nTPM]":"25.9","Single Cell Type RNA - Plasma cells [nTPM]":"28.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"24.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"56.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"30.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"169.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"72.5","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"32.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"24.7","Single Cell Type RNA - Spermatocytes [nTPM]":"32.5","Single Cell Type RNA - Spermatogonia [nTPM]":"7.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"26.1","Single Cell Type RNA - T-cells [nTPM]":"25.0","Single Cell Type RNA - Theca cells [nTPM]":"23.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"40.9","Single Cell Type RNA - Urothelial cells [nTPM]":"31.2"},{"Gene":"PACS2","Gene synonym":["KIAA0602","PACS1L"],"Ensembl":"ENSG00000179364","Gene description":"Phosphofurin acidic cluster sorting protein 2","Uniprot":["Q86VP3"],"Chromosome":"14","Position":"105300563-105398147","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Apoptosis","Host-virus interaction"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"136.6","skeletal muscle":"98.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"97.6","Oligodendrocytes":"169.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077892"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA077892":"AB_2686865"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.11e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.95e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.56e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Tissue RNA - adipose tissue [nTPM]":"22.4","Tissue RNA - adrenal gland [nTPM]":"16.1","Tissue RNA - amygdala [nTPM]":"48.4","Tissue RNA - appendix [nTPM]":"10.6","Tissue RNA - basal ganglia [nTPM]":"101.5","Tissue RNA - bone marrow [nTPM]":"9.0","Tissue RNA - breast [nTPM]":"18.7","Tissue RNA - cerebellum [nTPM]":"104.4","Tissue RNA - cerebral cortex [nTPM]":"61.3","Tissue RNA - cervix [nTPM]":"18.1","Tissue RNA - choroid plexus [nTPM]":"4.7","Tissue RNA - colon [nTPM]":"24.6","Tissue RNA - duodenum [nTPM]":"10.9","Tissue RNA - endometrium 1 [nTPM]":"21.0","Tissue RNA - epididymis [nTPM]":"5.4","Tissue RNA - esophagus [nTPM]":"11.2","Tissue RNA - fallopian tube [nTPM]":"19.0","Tissue RNA - gallbladder [nTPM]":"11.2","Tissue RNA - heart muscle [nTPM]":"23.8","Tissue RNA - hippocampal formation [nTPM]":"43.2","Tissue RNA - hypothalamus [nTPM]":"58.0","Tissue RNA - kidney [nTPM]":"12.4","Tissue RNA - liver [nTPM]":"6.9","Tissue RNA - lung [nTPM]":"16.1","Tissue RNA - lymph node [nTPM]":"8.5","Tissue RNA - medulla oblongata [nTPM]":"136.6","Tissue RNA - midbrain [nTPM]":"110.6","Tissue RNA - ovary [nTPM]":"20.0","Tissue RNA - pancreas [nTPM]":"28.8","Tissue RNA - parathyroid gland [nTPM]":"11.7","Tissue RNA - pituitary gland [nTPM]":"21.6","Tissue RNA - placenta [nTPM]":"8.8","Tissue RNA - pons [nTPM]":"119.6","Tissue RNA - prostate [nTPM]":"15.0","Tissue RNA - rectum [nTPM]":"6.6","Tissue RNA - retina [nTPM]":"12.2","Tissue RNA - salivary gland [nTPM]":"16.3","Tissue RNA - seminal vesicle [nTPM]":"11.5","Tissue RNA - skeletal muscle [nTPM]":"98.5","Tissue RNA - skin 1 [nTPM]":"12.6","Tissue RNA - small intestine [nTPM]":"14.2","Tissue RNA - smooth muscle [nTPM]":"10.0","Tissue RNA - spinal cord [nTPM]":"80.8","Tissue RNA - spleen [nTPM]":"16.0","Tissue RNA - stomach 1 [nTPM]":"17.4","Tissue RNA - testis [nTPM]":"19.8","Tissue RNA - thalamus [nTPM]":"106.1","Tissue RNA - thymus [nTPM]":"9.4","Tissue RNA - thyroid gland [nTPM]":"14.1","Tissue RNA - tongue [nTPM]":"46.1","Tissue RNA - tonsil [nTPM]":"5.5","Tissue RNA - urinary bladder [nTPM]":"19.3","Tissue RNA - vagina [nTPM]":"14.1","Tissue RNA - white matter [nTPM]":"126.8","Cell RNA - A-431 [nTPM]":"17.5","Cell RNA - A549 [nTPM]":"23.8","Cell RNA - AF22 [nTPM]":"21.9","Cell RNA - AN3-CA [nTPM]":"20.7","Cell RNA - ASC diff [nTPM]":"21.5","Cell RNA - ASC TERT1 [nTPM]":"20.6","Cell RNA - BEWO [nTPM]":"25.9","Cell RNA - BJ [nTPM]":"13.0","Cell RNA - BJ hTERT+ [nTPM]":"15.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.6","Cell RNA - CACO-2 [nTPM]":"10.4","Cell RNA - CAPAN-2 [nTPM]":"32.5","Cell RNA - Daudi [nTPM]":"19.0","Cell RNA - EFO-21 [nTPM]":"21.5","Cell RNA - fHDF\/TERT166 [nTPM]":"20.0","Cell RNA - GAMG [nTPM]":"14.1","Cell RNA - HaCaT [nTPM]":"19.7","Cell RNA - HAP1 [nTPM]":"13.5","Cell RNA - HBEC3-KT [nTPM]":"18.7","Cell RNA - HBF TERT88 [nTPM]":"7.9","Cell RNA - HDLM-2 [nTPM]":"23.7","Cell RNA - HEK 293 [nTPM]":"11.0","Cell RNA - HEL [nTPM]":"8.7","Cell RNA - HeLa [nTPM]":"10.0","Cell RNA - Hep G2 [nTPM]":"15.6","Cell RNA - HHSteC [nTPM]":"28.1","Cell RNA - HL-60 [nTPM]":"7.1","Cell RNA - HMC-1 [nTPM]":"15.0","Cell RNA - HSkMC [nTPM]":"24.1","Cell RNA - hTCEpi [nTPM]":"17.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.7","Cell RNA - hTERT-HME1 [nTPM]":"17.7","Cell RNA - hTERT-RPE1 [nTPM]":"13.9","Cell RNA - HUVEC TERT2 [nTPM]":"20.1","Cell RNA - JURKAT [nTPM]":"18.9","Cell RNA - K-562 [nTPM]":"5.4","Cell RNA - Karpas-707 [nTPM]":"17.2","Cell RNA - LHCN-M2 [nTPM]":"9.7","Cell RNA - MCF7 [nTPM]":"54.9","Cell RNA - MOLT-4 [nTPM]":"12.1","Cell RNA - NB-4 [nTPM]":"9.5","Cell RNA - NTERA-2 [nTPM]":"8.5","Cell RNA - OE19 [nTPM]":"22.1","Cell RNA - PC-3 [nTPM]":"19.4","Cell RNA - REH [nTPM]":"26.5","Cell RNA - RH-30 [nTPM]":"13.3","Cell RNA - RPMI-8226 [nTPM]":"12.1","Cell RNA - RPTEC TERT1 [nTPM]":"9.3","Cell RNA - RT4 [nTPM]":"39.7","Cell RNA - SCLC-21H [nTPM]":"49.0","Cell RNA - SH-SY5Y [nTPM]":"25.8","Cell RNA - SiHa [nTPM]":"12.4","Cell RNA - SK-BR-3 [nTPM]":"11.1","Cell RNA - SK-MEL-30 [nTPM]":"19.4","Cell RNA - SuSa [nTPM]":"13.7","Cell RNA - T-47d [nTPM]":"28.1","Cell RNA - THP-1 [nTPM]":"13.2","Cell RNA - TIME [nTPM]":"30.8","Cell RNA - U-138 MG [nTPM]":"16.2","Cell RNA - U-2 OS [nTPM]":"7.2","Cell RNA - U-2197 [nTPM]":"25.6","Cell RNA - U-251 MG [nTPM]":"13.1","Cell RNA - U-266\/70 [nTPM]":"22.3","Cell RNA - U-266\/84 [nTPM]":"15.6","Cell RNA - U-698 [nTPM]":"7.2","Cell RNA - U-87 MG [nTPM]":"24.6","Cell RNA - U-937 [nTPM]":"12.8","Cell RNA - WM-115 [nTPM]":"16.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"1.1","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"1.0","Blood RNA - non-classical monocyte [nTPM]":"1.9","Blood RNA - plasmacytoid DC [nTPM]":"2.3","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"48.4","Brain RNA - basal ganglia [nTPM]":"101.5","Brain RNA - cerebellum [nTPM]":"104.4","Brain RNA - cerebral cortex [nTPM]":"61.3","Brain RNA - hippocampal formation [nTPM]":"43.2","Brain RNA - hypothalamus [nTPM]":"58.0","Brain RNA - medulla oblongata [nTPM]":"136.6","Brain RNA - midbrain [nTPM]":"110.6","Brain RNA - pons [nTPM]":"119.6","Brain RNA - spinal cord [nTPM]":"80.8","Brain RNA - thalamus [nTPM]":"106.1","Brain RNA - white matter [nTPM]":"126.8","Single Cell Type RNA - Adipocytes [nTPM]":"28.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.7","Single Cell Type RNA - Astrocytes [nTPM]":"41.1","Single Cell Type RNA - B-cells [nTPM]":"3.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"30.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"21.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"12.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.3","Single Cell Type RNA - dendritic cells [nTPM]":"15.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"21.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"13.9","Single Cell Type RNA - Early spermatids [nTPM]":"77.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.7","Single Cell Type RNA - Endothelial cells [nTPM]":"21.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"4.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"29.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.2","Single Cell Type RNA - Fibroblasts [nTPM]":"15.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.3","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"28.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.2","Single Cell Type RNA - Hepatocytes [nTPM]":"10.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.6","Single Cell Type RNA - Horizontal cells [nTPM]":"97.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"41.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.6","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"15.7","Single Cell Type RNA - Langerhans cells [nTPM]":"23.0","Single Cell Type RNA - Late spermatids [nTPM]":"78.7","Single Cell Type RNA - Leydig cells [nTPM]":"17.4","Single Cell Type RNA - Macrophages [nTPM]":"17.1","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"30.9","Single Cell Type RNA - monocytes [nTPM]":"8.4","Single Cell Type RNA - Muller glia cells [nTPM]":"17.0","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"23.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"169.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.2","Single Cell Type RNA - Paneth cells [nTPM]":"12.6","Single Cell Type RNA - Peritubular cells [nTPM]":"16.6","Single Cell Type RNA - Plasma cells [nTPM]":"7.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"19.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.2","Single Cell Type RNA - Spermatocytes [nTPM]":"18.3","Single Cell Type RNA - Spermatogonia [nTPM]":"14.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - T-cells [nTPM]":"8.0","Single Cell Type RNA - Theca cells [nTPM]":"30.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.5","Single Cell Type RNA - Urothelial cells [nTPM]":"8.0"},{"Gene":"PADI3","Gene synonym":["PDI3"],"Ensembl":"ENSG00000142619","Gene description":"Peptidyl arginine deiminase 3","Uniprot":["Q9ULW8"],"Chromosome":"1","Position":"17249098-17284233","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"esophagus":"17.0","urinary bladder":"25.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"1.8","Ionocytes":"6.1","Squamous epithelial cells":"1.1","Urothelial cells":"7.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"urothelial cancer":"48.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"14.0","RT4":"17.4","T-47d":"12.8"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043739"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA043739":"AB_10959466"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.22e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.55e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-3"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"17.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"2.3","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.9","Tissue RNA - seminal vesicle [nTPM]":"3.4","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"3.7","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"25.6","Tissue RNA - vagina [nTPM]":"3.6","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"3.8","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.9","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"14.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"1.4","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"2.6","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"1.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.6","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"2.3","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"17.4","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"2.5","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"12.8","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"3.8","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"7.9"},{"Gene":"PADI4","Gene synonym":["PAD","PADI5","PDI4","PDI5"],"Ensembl":"ENSG00000159339","Gene description":"Peptidyl arginine deiminase 4","Uniprot":["Q9UM07"],"Chromosome":"1","Position":"17308195-17364004","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Immunity","Innate immunity","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"bone marrow":"105.1","lymphoid tissue":"29.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"8.3","granulocytes":"12.6","Macrophages":"14.6","monocytes":"22.3","NK-cells":"20.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"basophil":"79.9","classical monocyte":"71.3","eosinophil":"97.5","neutrophil":"183.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"183.0","monocytes":"71.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"1.2","RPMI-8226":"1.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017007","HPA042825"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"29000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017007":"AB_1854921","HPA042825":"AB_2678189"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.8","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.7","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"105.1","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.8","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"1.0","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"1.1","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.5","Tissue RNA - liver [nTPM]":"1.7","Tissue RNA - lung [nTPM]":"7.9","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"29.9","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"1.6","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.7","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"1.2","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"79.9","Blood RNA - classical monocyte [nTPM]":"71.3","Blood RNA - eosinophil [nTPM]":"97.5","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"5.7","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"1.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"13.9","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"2.6","Blood RNA - naive CD8 T-cell [nTPM]":"4.5","Blood RNA - neutrophil [nTPM]":"183.0","Blood RNA - NK-cell [nTPM]":"4.5","Blood RNA - non-classical monocyte [nTPM]":"1.8","Blood RNA - plasmacytoid DC [nTPM]":"6.2","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"35.8","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.8","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"8.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.6","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"12.6","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"14.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"22.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"4.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"2.3","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PADI6","Gene synonym":[],"Ensembl":"ENSG00000276747","Gene description":"Peptidyl arginine deiminase 6","Uniprot":["Q6TGC4"],"Chromosome":"1","Position":"17372196-17401699","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"1.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"white matter":"2.4"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.9","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PAK1","Gene synonym":[],"Ensembl":"ENSG00000149269","Gene description":"P21 (RAC1) activated kinase 1","Uniprot":["Q13153"],"Chromosome":"11","Position":"77322017-77474635","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["Apoptosis","Exocytosis"],"Molecular function":["Allosteric enzyme","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"219.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"classical monocyte":"182.2","eosinophil":"292.7","intermediate monocyte":"177.7","myeloid DC":"264.3","neutrophil":"431.8","non-classical monocyte":"202.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"dendritic cells":"264.3","granulocytes":"431.8","monocytes":"202.6"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003565","CAB005312"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"560000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB005312":"AB_2160720","HPA003565":"AB_1854935"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.87e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.15e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Tissue RNA - adipose tissue [nTPM]":"12.7","Tissue RNA - adrenal gland [nTPM]":"13.4","Tissue RNA - amygdala [nTPM]":"32.4","Tissue RNA - appendix [nTPM]":"33.9","Tissue RNA - basal ganglia [nTPM]":"44.5","Tissue RNA - bone marrow [nTPM]":"59.0","Tissue RNA - breast [nTPM]":"18.2","Tissue RNA - cerebellum [nTPM]":"13.9","Tissue RNA - cerebral cortex [nTPM]":"57.7","Tissue RNA - cervix [nTPM]":"21.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"43.2","Tissue RNA - duodenum [nTPM]":"43.1","Tissue RNA - endometrium 1 [nTPM]":"20.9","Tissue RNA - epididymis [nTPM]":"29.8","Tissue RNA - esophagus [nTPM]":"21.4","Tissue RNA - fallopian tube [nTPM]":"21.9","Tissue RNA - gallbladder [nTPM]":"30.9","Tissue RNA - heart muscle [nTPM]":"9.4","Tissue RNA - hippocampal formation [nTPM]":"58.3","Tissue RNA - hypothalamus [nTPM]":"8.0","Tissue RNA - kidney [nTPM]":"26.1","Tissue RNA - liver [nTPM]":"14.5","Tissue RNA - lung [nTPM]":"16.8","Tissue RNA - lymph node [nTPM]":"20.4","Tissue RNA - medulla oblongata [nTPM]":"19.2","Tissue RNA - midbrain [nTPM]":"12.2","Tissue RNA - ovary [nTPM]":"21.1","Tissue RNA - pancreas [nTPM]":"17.5","Tissue RNA - parathyroid gland [nTPM]":"20.5","Tissue RNA - pituitary gland [nTPM]":"20.7","Tissue RNA - placenta [nTPM]":"14.7","Tissue RNA - pons [nTPM]":"19.4","Tissue RNA - prostate [nTPM]":"19.1","Tissue RNA - rectum [nTPM]":"46.5","Tissue RNA - retina [nTPM]":"25.1","Tissue RNA - salivary gland [nTPM]":"19.9","Tissue RNA - seminal vesicle [nTPM]":"19.7","Tissue RNA - skeletal muscle [nTPM]":"87.0","Tissue RNA - skin 1 [nTPM]":"16.2","Tissue RNA - small intestine [nTPM]":"45.7","Tissue RNA - smooth muscle [nTPM]":"27.0","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"29.3","Tissue RNA - stomach 1 [nTPM]":"41.2","Tissue RNA - testis [nTPM]":"25.7","Tissue RNA - thalamus [nTPM]":"17.1","Tissue RNA - thymus [nTPM]":"29.1","Tissue RNA - thyroid gland [nTPM]":"40.6","Tissue RNA - tongue [nTPM]":"18.8","Tissue RNA - tonsil [nTPM]":"23.1","Tissue RNA - urinary bladder [nTPM]":"27.7","Tissue RNA - vagina [nTPM]":"20.7","Tissue RNA - white matter [nTPM]":"30.0","Cell RNA - A-431 [nTPM]":"39.9","Cell RNA - A549 [nTPM]":"26.7","Cell RNA - AF22 [nTPM]":"56.7","Cell RNA - AN3-CA [nTPM]":"25.5","Cell RNA - ASC diff [nTPM]":"22.8","Cell RNA - ASC TERT1 [nTPM]":"37.6","Cell RNA - BEWO [nTPM]":"45.9","Cell RNA - BJ [nTPM]":"44.6","Cell RNA - BJ hTERT+ [nTPM]":"32.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"42.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"48.7","Cell RNA - CACO-2 [nTPM]":"38.7","Cell RNA - CAPAN-2 [nTPM]":"52.8","Cell RNA - Daudi [nTPM]":"36.3","Cell RNA - EFO-21 [nTPM]":"16.0","Cell RNA - fHDF\/TERT166 [nTPM]":"39.4","Cell RNA - GAMG [nTPM]":"54.4","Cell RNA - HaCaT [nTPM]":"20.2","Cell RNA - HAP1 [nTPM]":"40.2","Cell RNA - HBEC3-KT [nTPM]":"47.8","Cell RNA - HBF TERT88 [nTPM]":"65.5","Cell RNA - HDLM-2 [nTPM]":"41.4","Cell RNA - HEK 293 [nTPM]":"32.6","Cell RNA - HEL [nTPM]":"38.2","Cell RNA - HeLa [nTPM]":"17.6","Cell RNA - Hep G2 [nTPM]":"2.3","Cell RNA - HHSteC [nTPM]":"15.3","Cell RNA - HL-60 [nTPM]":"64.3","Cell RNA - HMC-1 [nTPM]":"53.5","Cell RNA - HSkMC [nTPM]":"28.2","Cell RNA - hTCEpi [nTPM]":"28.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"49.2","Cell RNA - hTERT-HME1 [nTPM]":"73.1","Cell RNA - hTERT-RPE1 [nTPM]":"36.6","Cell RNA - HUVEC TERT2 [nTPM]":"10.1","Cell RNA - JURKAT [nTPM]":"41.3","Cell RNA - K-562 [nTPM]":"25.5","Cell RNA - Karpas-707 [nTPM]":"61.2","Cell RNA - LHCN-M2 [nTPM]":"77.6","Cell RNA - MCF7 [nTPM]":"2.9","Cell RNA - MOLT-4 [nTPM]":"42.3","Cell RNA - NB-4 [nTPM]":"30.2","Cell RNA - NTERA-2 [nTPM]":"84.5","Cell RNA - OE19 [nTPM]":"166.2","Cell RNA - PC-3 [nTPM]":"22.5","Cell RNA - REH [nTPM]":"62.6","Cell RNA - RH-30 [nTPM]":"72.3","Cell RNA - RPMI-8226 [nTPM]":"1.4","Cell RNA - RPTEC TERT1 [nTPM]":"10.6","Cell RNA - RT4 [nTPM]":"32.9","Cell RNA - SCLC-21H [nTPM]":"24.6","Cell RNA - SH-SY5Y [nTPM]":"23.9","Cell RNA - SiHa [nTPM]":"23.6","Cell RNA - SK-BR-3 [nTPM]":"9.7","Cell RNA - SK-MEL-30 [nTPM]":"19.5","Cell RNA - SuSa [nTPM]":"55.0","Cell RNA - T-47d [nTPM]":"45.4","Cell RNA - THP-1 [nTPM]":"29.0","Cell RNA - TIME [nTPM]":"0.9","Cell RNA - U-138 MG [nTPM]":"27.3","Cell RNA - U-2 OS [nTPM]":"47.5","Cell RNA - U-2197 [nTPM]":"148.9","Cell RNA - U-251 MG [nTPM]":"37.9","Cell RNA - U-266\/70 [nTPM]":"165.7","Cell RNA - U-266\/84 [nTPM]":"92.4","Cell RNA - U-698 [nTPM]":"23.4","Cell RNA - U-87 MG [nTPM]":"23.0","Cell RNA - U-937 [nTPM]":"42.5","Cell RNA - WM-115 [nTPM]":"30.6","Blood RNA - basophil [nTPM]":"2.5","Blood RNA - classical monocyte [nTPM]":"182.2","Blood RNA - eosinophil [nTPM]":"292.7","Blood RNA - gdT-cell [nTPM]":"11.2","Blood RNA - intermediate monocyte [nTPM]":"177.7","Blood RNA - MAIT T-cell [nTPM]":"9.4","Blood RNA - memory B-cell [nTPM]":"16.8","Blood RNA - memory CD4 T-cell [nTPM]":"8.4","Blood RNA - memory CD8 T-cell [nTPM]":"10.7","Blood RNA - myeloid DC [nTPM]":"264.3","Blood RNA - naive B-cell [nTPM]":"12.9","Blood RNA - naive CD4 T-cell [nTPM]":"7.4","Blood RNA - naive CD8 T-cell [nTPM]":"14.5","Blood RNA - neutrophil [nTPM]":"431.8","Blood RNA - NK-cell [nTPM]":"28.4","Blood RNA - non-classical monocyte [nTPM]":"202.6","Blood RNA - plasmacytoid DC [nTPM]":"22.9","Blood RNA - T-reg [nTPM]":"7.3","Blood RNA - total PBMC [nTPM]":"92.3","Brain RNA - amygdala [nTPM]":"32.4","Brain RNA - basal ganglia [nTPM]":"44.5","Brain RNA - cerebellum [nTPM]":"13.9","Brain RNA - cerebral cortex [nTPM]":"57.7","Brain RNA - hippocampal formation [nTPM]":"58.3","Brain RNA - hypothalamus [nTPM]":"8.0","Brain RNA - medulla oblongata [nTPM]":"19.2","Brain RNA - midbrain [nTPM]":"12.2","Brain RNA - pons [nTPM]":"19.4","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"17.1","Brain RNA - white matter [nTPM]":"30.0","Single Cell Type RNA - Adipocytes [nTPM]":"3.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.5","Single Cell Type RNA - Astrocytes [nTPM]":"24.2","Single Cell Type RNA - B-cells [nTPM]":"23.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"33.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"28.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.9","Single Cell Type RNA - Bipolar cells [nTPM]":"51.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"19.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"35.8","Single Cell Type RNA - Club cells [nTPM]":"30.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.4","Single Cell Type RNA - dendritic cells [nTPM]":"10.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"78.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"45.0","Single Cell Type RNA - Ductal cells [nTPM]":"32.4","Single Cell Type RNA - Early spermatids [nTPM]":"38.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"37.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.5","Single Cell Type RNA - Endothelial cells [nTPM]":"3.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"37.8","Single Cell Type RNA - Erythroid cells [nTPM]":"30.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"219.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"56.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"53.5","Single Cell Type RNA - Fibroblasts [nTPM]":"24.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"45.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"39.7","Single Cell Type RNA - granulocytes [nTPM]":"132.2","Single Cell Type RNA - Granulosa cells [nTPM]":"35.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"11.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"49.8","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"118.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"50.8","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"59.6","Single Cell Type RNA - Langerhans cells [nTPM]":"152.9","Single Cell Type RNA - Late spermatids [nTPM]":"28.3","Single Cell Type RNA - Leydig cells [nTPM]":"14.3","Single Cell Type RNA - Macrophages [nTPM]":"80.0","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"54.4","Single Cell Type RNA - monocytes [nTPM]":"121.7","Single Cell Type RNA - Muller glia cells [nTPM]":"14.9","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"53.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"70.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"50.9","Single Cell Type RNA - Paneth cells [nTPM]":"57.9","Single Cell Type RNA - Peritubular cells [nTPM]":"13.2","Single Cell Type RNA - Plasma cells [nTPM]":"28.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"28.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"47.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"55.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"39.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.4","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"25.2","Single Cell Type RNA - Spermatocytes [nTPM]":"50.4","Single Cell Type RNA - Spermatogonia [nTPM]":"53.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"95.0","Single Cell Type RNA - T-cells [nTPM]":"19.3","Single Cell Type RNA - Theca cells [nTPM]":"10.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"52.8","Single Cell Type RNA - Urothelial cells [nTPM]":"33.2"},{"Gene":"PAK3","Gene synonym":["bPAK","hPAK3","MRX30","MRX47"],"Ensembl":"ENSG00000077264","Gene description":"P21 (RAC1) activated kinase 3","Uniprot":["O75914"],"Chromosome":"X","Position":"110944285-111227361","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Allosteric enzyme","Developmental protein","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"31.9","pancreas":"42.7","pituitary gland":"13.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"104.1","Excitatory neurons":"364.0","Inhibitory neurons":"323.5","Oligodendrocyte precursor cells":"165.9","Peritubular cells":"81.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"1.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"MAIT T-cell":"1.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"T-cells":"1.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"10.8","HAP1":"9.9","HDLM-2":"12.4","NTERA-2":"9.7","SCLC-21H":"12.4","SH-SY5Y":"7.7","U-2197":"7.6","U-251 MG":"13.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044791","HPA060219"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA044791":null,"HPA060219":"AB_2684223"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.0","Tissue RNA - adrenal gland [nTPM]":"5.2","Tissue RNA - amygdala [nTPM]":"16.9","Tissue RNA - appendix [nTPM]":"1.6","Tissue RNA - basal ganglia [nTPM]":"16.2","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"5.2","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"17.6","Tissue RNA - cervix [nTPM]":"2.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.7","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"5.4","Tissue RNA - epididymis [nTPM]":"5.8","Tissue RNA - esophagus [nTPM]":"0.7","Tissue RNA - fallopian tube [nTPM]":"2.5","Tissue RNA - gallbladder [nTPM]":"1.6","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"17.8","Tissue RNA - hypothalamus [nTPM]":"31.9","Tissue RNA - kidney [nTPM]":"0.7","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.9","Tissue RNA - lymph node [nTPM]":"1.7","Tissue RNA - medulla oblongata [nTPM]":"1.6","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"6.2","Tissue RNA - pancreas [nTPM]":"42.7","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"13.7","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"6.0","Tissue RNA - prostate [nTPM]":"3.4","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"7.0","Tissue RNA - salivary gland [nTPM]":"2.2","Tissue RNA - seminal vesicle [nTPM]":"4.8","Tissue RNA - skeletal muscle [nTPM]":"1.6","Tissue RNA - skin 1 [nTPM]":"1.3","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"4.7","Tissue RNA - spinal cord [nTPM]":"0.4","Tissue RNA - spleen [nTPM]":"2.0","Tissue RNA - stomach 1 [nTPM]":"2.0","Tissue RNA - testis [nTPM]":"2.6","Tissue RNA - thalamus [nTPM]":"13.2","Tissue RNA - thymus [nTPM]":"0.6","Tissue RNA - thyroid gland [nTPM]":"6.2","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"0.8","Tissue RNA - urinary bladder [nTPM]":"0.9","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"2.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.7","Cell RNA - AF22 [nTPM]":"1.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"10.8","Cell RNA - fHDF\/TERT166 [nTPM]":"1.2","Cell RNA - GAMG [nTPM]":"1.6","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"9.9","Cell RNA - HBEC3-KT [nTPM]":"0.6","Cell RNA - HBF TERT88 [nTPM]":"1.3","Cell RNA - HDLM-2 [nTPM]":"12.4","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"1.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"2.2","Cell RNA - hTERT-RPE1 [nTPM]":"5.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"9.7","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"2.2","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"4.3","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.8","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"12.4","Cell RNA - SH-SY5Y [nTPM]":"7.7","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"6.6","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.7","Cell RNA - U-2 OS [nTPM]":"4.7","Cell RNA - U-2197 [nTPM]":"7.6","Cell RNA - U-251 MG [nTPM]":"13.6","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"1.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"16.9","Brain RNA - basal ganglia [nTPM]":"16.2","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"17.6","Brain RNA - hippocampal formation [nTPM]":"17.8","Brain RNA - hypothalamus [nTPM]":"31.9","Brain RNA - medulla oblongata [nTPM]":"1.6","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"6.0","Brain RNA - spinal cord [nTPM]":"0.4","Brain RNA - thalamus [nTPM]":"13.2","Brain RNA - white matter [nTPM]":"2.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"16.0","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"104.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"0.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"4.7","Single Cell Type RNA - Early spermatids [nTPM]":"4.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.8","Single Cell Type RNA - Endothelial cells [nTPM]":"2.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"364.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"10.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.7","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"21.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"323.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"5.7","Single Cell Type RNA - Late spermatids [nTPM]":"7.0","Single Cell Type RNA - Leydig cells [nTPM]":"34.2","Single Cell Type RNA - Macrophages [nTPM]":"1.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"27.5","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"165.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"81.3","Single Cell Type RNA - Plasma cells [nTPM]":"1.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.8","Single Cell Type RNA - Spermatocytes [nTPM]":"1.4","Single Cell Type RNA - Spermatogonia [nTPM]":"1.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.7","Single Cell Type RNA - T-cells [nTPM]":"2.4","Single Cell Type RNA - Theca cells [nTPM]":"29.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.9"},{"Gene":"PANK2","Gene synonym":["C20orf48","FLJ11729","HARP","HSS","NBIA1","PKAN"],"Ensembl":"ENSG00000125779","Gene description":"Pantothenate kinase 2","Uniprot":["Q9BZ23"],"Chromosome":"20","Position":"3888839-3929887","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Angiogenesis","Coenzyme A biosynthesis"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008440"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA008440":"AB_1079559"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.20e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Tissue RNA - adipose tissue [nTPM]":"13.0","Tissue RNA - adrenal gland [nTPM]":"12.3","Tissue RNA - amygdala [nTPM]":"14.5","Tissue RNA - appendix [nTPM]":"16.8","Tissue RNA - basal ganglia [nTPM]":"13.7","Tissue RNA - bone marrow [nTPM]":"20.9","Tissue RNA - breast [nTPM]":"12.2","Tissue RNA - cerebellum [nTPM]":"15.3","Tissue RNA - cerebral cortex [nTPM]":"15.9","Tissue RNA - cervix [nTPM]":"11.9","Tissue RNA - choroid plexus [nTPM]":"14.1","Tissue RNA - colon [nTPM]":"11.4","Tissue RNA - duodenum [nTPM]":"8.4","Tissue RNA - endometrium 1 [nTPM]":"11.0","Tissue RNA - epididymis [nTPM]":"11.3","Tissue RNA - esophagus [nTPM]":"20.0","Tissue RNA - fallopian tube [nTPM]":"16.3","Tissue RNA - gallbladder [nTPM]":"12.1","Tissue RNA - heart muscle [nTPM]":"8.7","Tissue RNA - hippocampal formation [nTPM]":"15.5","Tissue RNA - hypothalamus [nTPM]":"13.5","Tissue RNA - kidney [nTPM]":"15.7","Tissue RNA - liver [nTPM]":"18.3","Tissue RNA - lung [nTPM]":"14.1","Tissue RNA - lymph node [nTPM]":"18.5","Tissue RNA - medulla oblongata [nTPM]":"12.7","Tissue RNA - midbrain [nTPM]":"14.1","Tissue RNA - ovary [nTPM]":"12.9","Tissue RNA - pancreas [nTPM]":"10.3","Tissue RNA - parathyroid gland [nTPM]":"10.9","Tissue RNA - pituitary gland [nTPM]":"8.9","Tissue RNA - placenta [nTPM]":"15.3","Tissue RNA - pons [nTPM]":"13.3","Tissue RNA - prostate [nTPM]":"12.0","Tissue RNA - rectum [nTPM]":"14.2","Tissue RNA - retina [nTPM]":"10.3","Tissue RNA - salivary gland [nTPM]":"11.9","Tissue RNA - seminal vesicle [nTPM]":"10.7","Tissue RNA - skeletal muscle [nTPM]":"9.6","Tissue RNA - skin 1 [nTPM]":"11.7","Tissue RNA - small intestine [nTPM]":"11.6","Tissue RNA - smooth muscle [nTPM]":"13.7","Tissue RNA - spinal cord [nTPM]":"12.7","Tissue RNA - spleen [nTPM]":"14.9","Tissue RNA - stomach 1 [nTPM]":"9.1","Tissue RNA - testis [nTPM]":"25.9","Tissue RNA - thalamus [nTPM]":"13.9","Tissue RNA - thymus [nTPM]":"16.8","Tissue RNA - thyroid gland [nTPM]":"15.4","Tissue RNA - tongue [nTPM]":"11.2","Tissue RNA - tonsil [nTPM]":"22.0","Tissue RNA - urinary bladder [nTPM]":"15.6","Tissue RNA - vagina [nTPM]":"9.9","Tissue RNA - white matter [nTPM]":"12.4","Cell RNA - A-431 [nTPM]":"39.3","Cell RNA - A549 [nTPM]":"29.4","Cell RNA - AF22 [nTPM]":"33.7","Cell RNA - AN3-CA [nTPM]":"18.6","Cell RNA - ASC diff [nTPM]":"39.3","Cell RNA - ASC TERT1 [nTPM]":"32.6","Cell RNA - BEWO [nTPM]":"15.0","Cell RNA - BJ [nTPM]":"25.6","Cell RNA - BJ hTERT+ [nTPM]":"34.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"38.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"48.3","Cell RNA - CACO-2 [nTPM]":"40.8","Cell RNA - CAPAN-2 [nTPM]":"25.4","Cell RNA - Daudi [nTPM]":"34.6","Cell RNA - EFO-21 [nTPM]":"10.6","Cell RNA - fHDF\/TERT166 [nTPM]":"34.9","Cell RNA - GAMG [nTPM]":"70.2","Cell RNA - HaCaT [nTPM]":"34.9","Cell RNA - HAP1 [nTPM]":"34.7","Cell RNA - HBEC3-KT [nTPM]":"57.3","Cell RNA - HBF TERT88 [nTPM]":"49.3","Cell RNA - HDLM-2 [nTPM]":"8.8","Cell RNA - HEK 293 [nTPM]":"9.8","Cell RNA - HEL [nTPM]":"47.4","Cell RNA - HeLa [nTPM]":"22.7","Cell RNA - Hep G2 [nTPM]":"80.2","Cell RNA - HHSteC [nTPM]":"33.3","Cell RNA - HL-60 [nTPM]":"33.6","Cell RNA - HMC-1 [nTPM]":"15.9","Cell RNA - HSkMC [nTPM]":"28.7","Cell RNA - hTCEpi [nTPM]":"26.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"39.7","Cell RNA - hTERT-HME1 [nTPM]":"28.7","Cell RNA - hTERT-RPE1 [nTPM]":"17.0","Cell RNA - HUVEC TERT2 [nTPM]":"36.0","Cell RNA - JURKAT [nTPM]":"23.3","Cell RNA - K-562 [nTPM]":"34.7","Cell RNA - Karpas-707 [nTPM]":"30.5","Cell RNA - LHCN-M2 [nTPM]":"42.5","Cell RNA - MCF7 [nTPM]":"11.7","Cell RNA - MOLT-4 [nTPM]":"30.0","Cell RNA - NB-4 [nTPM]":"30.3","Cell RNA - NTERA-2 [nTPM]":"28.8","Cell RNA - OE19 [nTPM]":"22.9","Cell RNA - PC-3 [nTPM]":"19.5","Cell RNA - REH [nTPM]":"20.3","Cell RNA - RH-30 [nTPM]":"46.0","Cell RNA - RPMI-8226 [nTPM]":"22.4","Cell RNA - RPTEC TERT1 [nTPM]":"26.2","Cell RNA - RT4 [nTPM]":"45.7","Cell RNA - SCLC-21H [nTPM]":"36.2","Cell RNA - SH-SY5Y [nTPM]":"16.7","Cell RNA - SiHa [nTPM]":"30.0","Cell RNA - SK-BR-3 [nTPM]":"44.3","Cell RNA - SK-MEL-30 [nTPM]":"78.1","Cell RNA - SuSa [nTPM]":"32.6","Cell RNA - T-47d [nTPM]":"23.6","Cell RNA - THP-1 [nTPM]":"28.1","Cell RNA - TIME [nTPM]":"24.6","Cell RNA - U-138 MG [nTPM]":"47.7","Cell RNA - U-2 OS [nTPM]":"17.8","Cell RNA - U-2197 [nTPM]":"60.7","Cell RNA - U-251 MG [nTPM]":"43.3","Cell RNA - U-266\/70 [nTPM]":"14.0","Cell RNA - U-266\/84 [nTPM]":"50.8","Cell RNA - U-698 [nTPM]":"23.3","Cell RNA - U-87 MG [nTPM]":"15.0","Cell RNA - U-937 [nTPM]":"30.7","Cell RNA - WM-115 [nTPM]":"34.2","Blood RNA - basophil [nTPM]":"3.0","Blood RNA - classical monocyte [nTPM]":"10.5","Blood RNA - eosinophil [nTPM]":"3.4","Blood RNA - gdT-cell [nTPM]":"3.6","Blood RNA - intermediate monocyte [nTPM]":"11.1","Blood RNA - MAIT T-cell [nTPM]":"3.5","Blood RNA - memory B-cell [nTPM]":"3.8","Blood RNA - memory CD4 T-cell [nTPM]":"3.7","Blood RNA - memory CD8 T-cell [nTPM]":"3.4","Blood RNA - myeloid DC [nTPM]":"8.5","Blood RNA - naive B-cell [nTPM]":"4.5","Blood RNA - naive CD4 T-cell [nTPM]":"4.1","Blood RNA - naive CD8 T-cell [nTPM]":"3.4","Blood RNA - neutrophil [nTPM]":"5.9","Blood RNA - NK-cell [nTPM]":"6.8","Blood RNA - non-classical monocyte [nTPM]":"9.4","Blood RNA - plasmacytoid DC [nTPM]":"3.0","Blood RNA - T-reg [nTPM]":"5.9","Blood RNA - total PBMC [nTPM]":"4.0","Brain RNA - amygdala [nTPM]":"14.5","Brain RNA - basal ganglia [nTPM]":"13.7","Brain RNA - cerebellum [nTPM]":"15.3","Brain RNA - cerebral cortex [nTPM]":"15.9","Brain RNA - hippocampal formation [nTPM]":"15.5","Brain RNA - hypothalamus [nTPM]":"13.5","Brain RNA - medulla oblongata [nTPM]":"12.7","Brain RNA - midbrain [nTPM]":"14.1","Brain RNA - pons [nTPM]":"13.3","Brain RNA - spinal cord [nTPM]":"12.7","Brain RNA - thalamus [nTPM]":"13.9","Brain RNA - white matter [nTPM]":"12.4","Single Cell Type RNA - Adipocytes [nTPM]":"23.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.7","Single Cell Type RNA - Astrocytes [nTPM]":"23.8","Single Cell Type RNA - B-cells [nTPM]":"29.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"25.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"41.5","Single Cell Type RNA - Bipolar cells [nTPM]":"22.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"13.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"29.4","Single Cell Type RNA - dendritic cells [nTPM]":"38.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"19.4","Single Cell Type RNA - Early spermatids [nTPM]":"83.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"24.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.6","Single Cell Type RNA - Endothelial cells [nTPM]":"26.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.3","Single Cell Type RNA - Erythroid cells [nTPM]":"42.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"28.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"36.0","Single Cell Type RNA - Fibroblasts [nTPM]":"21.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"24.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.1","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"20.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.0","Single Cell Type RNA - Hepatocytes [nTPM]":"14.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"33.8","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.7","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"52.8","Single Cell Type RNA - Langerhans cells [nTPM]":"37.9","Single Cell Type RNA - Late spermatids [nTPM]":"17.3","Single Cell Type RNA - Leydig cells [nTPM]":"21.1","Single Cell Type RNA - Macrophages [nTPM]":"34.3","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"29.0","Single Cell Type RNA - monocytes [nTPM]":"55.0","Single Cell Type RNA - Muller glia cells [nTPM]":"14.1","Single Cell Type RNA - NK-cells [nTPM]":"35.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"23.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.9","Single Cell Type RNA - Paneth cells [nTPM]":"12.8","Single Cell Type RNA - Peritubular cells [nTPM]":"22.6","Single Cell Type RNA - Plasma cells [nTPM]":"33.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"20.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.1","Single Cell Type RNA - Spermatocytes [nTPM]":"54.6","Single Cell Type RNA - Spermatogonia [nTPM]":"25.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"37.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"18.6","Single Cell Type RNA - T-cells [nTPM]":"31.6","Single Cell Type RNA - Theca cells [nTPM]":"21.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.0","Single Cell Type RNA - Urothelial cells [nTPM]":"20.0"},{"Gene":"PANX1","Gene synonym":["MRS1","PX1","UNQ2529"],"Ensembl":"ENSG00000110218","Gene description":"Pannexin 1","Uniprot":["Q96RD7"],"Chromosome":"11","Position":"94128841-94181968","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Differentiation","Ion transport","Oogenesis","Transport"],"Molecular function":["Calcium channel","Ion channel"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"102.0","Suprabasal keratinocytes":"72.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016930"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 28: Keratinocytes - Keratinization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA016930":"AB_1854954"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.13e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.09e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.49e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Tissue RNA - adipose tissue [nTPM]":"11.4","Tissue RNA - adrenal gland [nTPM]":"7.2","Tissue RNA - amygdala [nTPM]":"5.1","Tissue RNA - appendix [nTPM]":"12.1","Tissue RNA - basal ganglia [nTPM]":"5.2","Tissue RNA - bone marrow [nTPM]":"4.1","Tissue RNA - breast [nTPM]":"6.4","Tissue RNA - cerebellum [nTPM]":"1.2","Tissue RNA - cerebral cortex [nTPM]":"5.5","Tissue RNA - cervix [nTPM]":"7.9","Tissue RNA - choroid plexus [nTPM]":"2.7","Tissue RNA - colon [nTPM]":"8.4","Tissue RNA - duodenum [nTPM]":"5.4","Tissue RNA - endometrium 1 [nTPM]":"8.5","Tissue RNA - epididymis [nTPM]":"5.2","Tissue RNA - esophagus [nTPM]":"7.9","Tissue RNA - fallopian tube [nTPM]":"5.2","Tissue RNA - gallbladder [nTPM]":"11.5","Tissue RNA - heart muscle [nTPM]":"9.9","Tissue RNA - hippocampal formation [nTPM]":"5.0","Tissue RNA - hypothalamus [nTPM]":"7.1","Tissue RNA - kidney [nTPM]":"6.9","Tissue RNA - liver [nTPM]":"16.8","Tissue RNA - lung [nTPM]":"10.2","Tissue RNA - lymph node [nTPM]":"6.4","Tissue RNA - medulla oblongata [nTPM]":"2.1","Tissue RNA - midbrain [nTPM]":"2.9","Tissue RNA - ovary [nTPM]":"7.1","Tissue RNA - pancreas [nTPM]":"7.4","Tissue RNA - parathyroid gland [nTPM]":"4.4","Tissue RNA - pituitary gland [nTPM]":"4.7","Tissue RNA - placenta [nTPM]":"9.7","Tissue RNA - pons [nTPM]":"3.3","Tissue RNA - prostate [nTPM]":"7.7","Tissue RNA - rectum [nTPM]":"7.2","Tissue RNA - retina [nTPM]":"3.1","Tissue RNA - salivary gland [nTPM]":"6.0","Tissue RNA - seminal vesicle [nTPM]":"7.0","Tissue RNA - skeletal muscle [nTPM]":"20.8","Tissue RNA - skin 1 [nTPM]":"8.3","Tissue RNA - small intestine [nTPM]":"5.8","Tissue RNA - smooth muscle [nTPM]":"12.8","Tissue RNA - spinal cord [nTPM]":"2.8","Tissue RNA - spleen [nTPM]":"5.8","Tissue RNA - stomach 1 [nTPM]":"7.4","Tissue RNA - testis [nTPM]":"9.9","Tissue RNA - thalamus [nTPM]":"4.9","Tissue RNA - thymus [nTPM]":"8.1","Tissue RNA - thyroid gland [nTPM]":"8.7","Tissue RNA - tongue [nTPM]":"10.8","Tissue RNA - tonsil [nTPM]":"7.0","Tissue RNA - urinary bladder [nTPM]":"21.9","Tissue RNA - vagina [nTPM]":"6.5","Tissue RNA - white matter [nTPM]":"2.7","Cell RNA - A-431 [nTPM]":"24.6","Cell RNA - A549 [nTPM]":"10.2","Cell RNA - AF22 [nTPM]":"26.2","Cell RNA - AN3-CA [nTPM]":"16.0","Cell RNA - ASC diff [nTPM]":"23.9","Cell RNA - ASC TERT1 [nTPM]":"32.3","Cell RNA - BEWO [nTPM]":"17.1","Cell RNA - BJ [nTPM]":"29.8","Cell RNA - BJ hTERT+ [nTPM]":"63.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"25.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"30.7","Cell RNA - CACO-2 [nTPM]":"26.2","Cell RNA - CAPAN-2 [nTPM]":"37.6","Cell RNA - Daudi [nTPM]":"7.8","Cell RNA - EFO-21 [nTPM]":"27.3","Cell RNA - fHDF\/TERT166 [nTPM]":"30.5","Cell RNA - GAMG [nTPM]":"46.1","Cell RNA - HaCaT [nTPM]":"50.5","Cell RNA - HAP1 [nTPM]":"20.9","Cell RNA - HBEC3-KT [nTPM]":"49.2","Cell RNA - HBF TERT88 [nTPM]":"25.2","Cell RNA - HDLM-2 [nTPM]":"33.6","Cell RNA - HEK 293 [nTPM]":"10.9","Cell RNA - HEL [nTPM]":"36.0","Cell RNA - HeLa [nTPM]":"10.2","Cell RNA - Hep G2 [nTPM]":"13.5","Cell RNA - HHSteC [nTPM]":"23.1","Cell RNA - HL-60 [nTPM]":"18.7","Cell RNA - HMC-1 [nTPM]":"31.0","Cell RNA - HSkMC [nTPM]":"25.7","Cell RNA - hTCEpi [nTPM]":"33.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.8","Cell RNA - hTERT-HME1 [nTPM]":"29.2","Cell RNA - hTERT-RPE1 [nTPM]":"16.1","Cell RNA - HUVEC TERT2 [nTPM]":"21.2","Cell RNA - JURKAT [nTPM]":"20.1","Cell RNA - K-562 [nTPM]":"23.8","Cell RNA - Karpas-707 [nTPM]":"27.5","Cell RNA - LHCN-M2 [nTPM]":"28.3","Cell RNA - MCF7 [nTPM]":"7.8","Cell RNA - MOLT-4 [nTPM]":"31.3","Cell RNA - NB-4 [nTPM]":"4.4","Cell RNA - NTERA-2 [nTPM]":"21.0","Cell RNA - OE19 [nTPM]":"19.7","Cell RNA - PC-3 [nTPM]":"18.2","Cell RNA - REH [nTPM]":"36.7","Cell RNA - RH-30 [nTPM]":"35.0","Cell RNA - RPMI-8226 [nTPM]":"9.7","Cell RNA - RPTEC TERT1 [nTPM]":"16.3","Cell RNA - RT4 [nTPM]":"24.0","Cell RNA - SCLC-21H [nTPM]":"11.0","Cell RNA - SH-SY5Y [nTPM]":"31.9","Cell RNA - SiHa [nTPM]":"20.9","Cell RNA - SK-BR-3 [nTPM]":"11.9","Cell RNA - SK-MEL-30 [nTPM]":"14.4","Cell RNA - SuSa [nTPM]":"13.3","Cell RNA - T-47d [nTPM]":"25.2","Cell RNA - THP-1 [nTPM]":"9.5","Cell RNA - TIME [nTPM]":"15.4","Cell RNA - U-138 MG [nTPM]":"49.5","Cell RNA - U-2 OS [nTPM]":"25.5","Cell RNA - U-2197 [nTPM]":"16.4","Cell RNA - U-251 MG [nTPM]":"29.9","Cell RNA - U-266\/70 [nTPM]":"4.5","Cell RNA - U-266\/84 [nTPM]":"18.2","Cell RNA - U-698 [nTPM]":"12.6","Cell RNA - U-87 MG [nTPM]":"20.6","Cell RNA - U-937 [nTPM]":"19.0","Cell RNA - WM-115 [nTPM]":"32.2","Blood RNA - basophil [nTPM]":"3.2","Blood RNA - classical monocyte [nTPM]":"4.0","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"2.1","Blood RNA - intermediate monocyte [nTPM]":"2.2","Blood RNA - MAIT T-cell [nTPM]":"2.4","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"1.7","Blood RNA - memory CD8 T-cell [nTPM]":"2.3","Blood RNA - myeloid DC [nTPM]":"2.7","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.6","Blood RNA - naive CD8 T-cell [nTPM]":"1.7","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"2.6","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"2.9","Blood RNA - total PBMC [nTPM]":"3.2","Brain RNA - amygdala [nTPM]":"5.1","Brain RNA - basal ganglia [nTPM]":"5.2","Brain RNA - cerebellum [nTPM]":"1.2","Brain RNA - cerebral cortex [nTPM]":"5.5","Brain RNA - hippocampal formation [nTPM]":"5.0","Brain RNA - hypothalamus [nTPM]":"7.1","Brain RNA - medulla oblongata [nTPM]":"2.1","Brain RNA - midbrain [nTPM]":"2.9","Brain RNA - pons [nTPM]":"3.3","Brain RNA - spinal cord [nTPM]":"2.8","Brain RNA - thalamus [nTPM]":"4.9","Brain RNA - white matter [nTPM]":"2.7","Single Cell Type RNA - Adipocytes [nTPM]":"3.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.7","Single Cell Type RNA - Astrocytes [nTPM]":"4.6","Single Cell Type RNA - B-cells [nTPM]":"6.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"102.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"4.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.8","Single Cell Type RNA - dendritic cells [nTPM]":"5.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"15.7","Single Cell Type RNA - Early spermatids [nTPM]":"5.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.0","Single Cell Type RNA - Endothelial cells [nTPM]":"6.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"32.4","Single Cell Type RNA - Fibroblasts [nTPM]":"17.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.9","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"4.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"8.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.1","Single Cell Type RNA - Langerhans cells [nTPM]":"21.6","Single Cell Type RNA - Late spermatids [nTPM]":"3.9","Single Cell Type RNA - Leydig cells [nTPM]":"4.4","Single Cell Type RNA - Macrophages [nTPM]":"11.5","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"3.7","Single Cell Type RNA - Muller glia cells [nTPM]":"1.1","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"26.1","Single Cell Type RNA - Paneth cells [nTPM]":"3.4","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"7.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.6","Single Cell Type RNA - Spermatocytes [nTPM]":"1.7","Single Cell Type RNA - Spermatogonia [nTPM]":"8.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"72.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.8","Single Cell Type RNA - T-cells [nTPM]":"6.6","Single Cell Type RNA - Theca cells [nTPM]":"10.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.2","Single Cell Type RNA - Urothelial cells [nTPM]":"12.7"},{"Gene":"PAPSS2","Gene synonym":["ATPSK2"],"Ensembl":"ENSG00000198682","Gene description":"3'-phosphoadenosine 5'-phosphosulfate synthase 2","Uniprot":["O95340"],"Chromosome":"10","Position":"87659613-87747705","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Multifunctional enzyme","Nucleotidyltransferase","Transferase"],"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"135.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"240.4","Distal enterocytes":"202.4","Hepatocytes":"111.5","Proximal enterocytes":"181.3","Theca cells":"96.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"intermediate monocyte":"4.0","myeloid DC":"2.1","non-classical monocyte":"7.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"dendritic cells":"2.1","monocytes":"7.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ":"189.8","fHDF\/TERT166":"473.2","HHSteC":"196.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071224","HPA075267"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"16000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA071224":"AB_2686366","HPA075267":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.33e-6"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.58e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.21e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-3"},"Tissue RNA - adipose tissue [nTPM]":"33.3","Tissue RNA - adrenal gland [nTPM]":"135.2","Tissue RNA - amygdala [nTPM]":"6.3","Tissue RNA - appendix [nTPM]":"26.6","Tissue RNA - basal ganglia [nTPM]":"7.0","Tissue RNA - bone marrow [nTPM]":"2.0","Tissue RNA - breast [nTPM]":"20.9","Tissue RNA - cerebellum [nTPM]":"6.2","Tissue RNA - cerebral cortex [nTPM]":"9.5","Tissue RNA - cervix [nTPM]":"17.8","Tissue RNA - choroid plexus [nTPM]":"6.2","Tissue RNA - colon [nTPM]":"79.9","Tissue RNA - duodenum [nTPM]":"29.5","Tissue RNA - endometrium 1 [nTPM]":"8.5","Tissue RNA - epididymis [nTPM]":"3.1","Tissue RNA - esophagus [nTPM]":"10.2","Tissue RNA - fallopian tube [nTPM]":"12.4","Tissue RNA - gallbladder [nTPM]":"20.7","Tissue RNA - heart muscle [nTPM]":"11.6","Tissue RNA - hippocampal formation [nTPM]":"5.8","Tissue RNA - hypothalamus [nTPM]":"6.2","Tissue RNA - kidney [nTPM]":"23.8","Tissue RNA - liver [nTPM]":"77.0","Tissue RNA - lung [nTPM]":"70.4","Tissue RNA - lymph node [nTPM]":"11.0","Tissue RNA - medulla oblongata [nTPM]":"6.9","Tissue RNA - midbrain [nTPM]":"6.6","Tissue RNA - ovary [nTPM]":"27.5","Tissue RNA - pancreas [nTPM]":"26.1","Tissue RNA - parathyroid gland [nTPM]":"2.1","Tissue RNA - pituitary gland [nTPM]":"3.0","Tissue RNA - placenta [nTPM]":"58.5","Tissue RNA - pons [nTPM]":"7.5","Tissue RNA - prostate [nTPM]":"6.7","Tissue RNA - rectum [nTPM]":"64.3","Tissue RNA - retina [nTPM]":"2.3","Tissue RNA - salivary gland [nTPM]":"16.4","Tissue RNA - seminal vesicle [nTPM]":"3.4","Tissue RNA - skeletal muscle [nTPM]":"4.7","Tissue RNA - skin 1 [nTPM]":"3.5","Tissue RNA - small intestine [nTPM]":"61.8","Tissue RNA - smooth muscle [nTPM]":"16.7","Tissue RNA - spinal cord [nTPM]":"6.8","Tissue RNA - spleen [nTPM]":"8.5","Tissue RNA - stomach 1 [nTPM]":"9.2","Tissue RNA - testis [nTPM]":"11.7","Tissue RNA - thalamus [nTPM]":"8.0","Tissue RNA - thymus [nTPM]":"3.0","Tissue RNA - thyroid gland [nTPM]":"21.3","Tissue RNA - tongue [nTPM]":"8.7","Tissue RNA - tonsil [nTPM]":"14.8","Tissue RNA - urinary bladder [nTPM]":"16.6","Tissue RNA - vagina [nTPM]":"11.5","Tissue RNA - white matter [nTPM]":"7.2","Cell RNA - A-431 [nTPM]":"19.9","Cell RNA - A549 [nTPM]":"20.0","Cell RNA - AF22 [nTPM]":"6.4","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"129.4","Cell RNA - ASC TERT1 [nTPM]":"164.8","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"189.8","Cell RNA - BJ hTERT+ [nTPM]":"157.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"110.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"79.9","Cell RNA - CACO-2 [nTPM]":"1.0","Cell RNA - CAPAN-2 [nTPM]":"4.1","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"9.8","Cell RNA - fHDF\/TERT166 [nTPM]":"473.2","Cell RNA - GAMG [nTPM]":"3.5","Cell RNA - HaCaT [nTPM]":"8.5","Cell RNA - HAP1 [nTPM]":"13.9","Cell RNA - HBEC3-KT [nTPM]":"13.3","Cell RNA - HBF TERT88 [nTPM]":"125.2","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"10.0","Cell RNA - HEL [nTPM]":"8.8","Cell RNA - HeLa [nTPM]":"13.4","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"196.5","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"3.8","Cell RNA - HSkMC [nTPM]":"58.7","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"63.7","Cell RNA - hTERT-HME1 [nTPM]":"5.2","Cell RNA - hTERT-RPE1 [nTPM]":"135.6","Cell RNA - HUVEC TERT2 [nTPM]":"94.2","Cell RNA - JURKAT [nTPM]":"1.4","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"89.4","Cell RNA - LHCN-M2 [nTPM]":"79.2","Cell RNA - MCF7 [nTPM]":"74.1","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.7","Cell RNA - NTERA-2 [nTPM]":"7.4","Cell RNA - OE19 [nTPM]":"4.8","Cell RNA - PC-3 [nTPM]":"24.1","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"117.5","Cell RNA - RT4 [nTPM]":"8.7","Cell RNA - SCLC-21H [nTPM]":"0.9","Cell RNA - SH-SY5Y [nTPM]":"1.6","Cell RNA - SiHa [nTPM]":"92.5","Cell RNA - SK-BR-3 [nTPM]":"3.3","Cell RNA - SK-MEL-30 [nTPM]":"1.1","Cell RNA - SuSa [nTPM]":"12.6","Cell RNA - T-47d [nTPM]":"13.5","Cell RNA - THP-1 [nTPM]":"5.3","Cell RNA - TIME [nTPM]":"120.0","Cell RNA - U-138 MG [nTPM]":"38.2","Cell RNA - U-2 OS [nTPM]":"22.5","Cell RNA - U-2197 [nTPM]":"131.5","Cell RNA - U-251 MG [nTPM]":"13.9","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"1.0","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"18.3","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"4.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"2.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"7.7","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"6.3","Brain RNA - basal ganglia [nTPM]":"7.0","Brain RNA - cerebellum [nTPM]":"6.2","Brain RNA - cerebral cortex [nTPM]":"9.5","Brain RNA - hippocampal formation [nTPM]":"5.8","Brain RNA - hypothalamus [nTPM]":"6.2","Brain RNA - medulla oblongata [nTPM]":"6.9","Brain RNA - midbrain [nTPM]":"6.6","Brain RNA - pons [nTPM]":"7.5","Brain RNA - spinal cord [nTPM]":"6.8","Brain RNA - thalamus [nTPM]":"8.0","Brain RNA - white matter [nTPM]":"7.2","Single Cell Type RNA - Adipocytes [nTPM]":"49.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"240.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"38.2","Single Cell Type RNA - Astrocytes [nTPM]":"3.6","Single Cell Type RNA - B-cells [nTPM]":"2.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"13.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"202.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"6.4","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.7","Single Cell Type RNA - Endothelial cells [nTPM]":"23.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.6","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.8","Single Cell Type RNA - Fibroblasts [nTPM]":"36.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"20.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"36.0","Single Cell Type RNA - Hepatocytes [nTPM]":"111.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"27.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.5","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"29.8","Single Cell Type RNA - Langerhans cells [nTPM]":"50.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"17.4","Single Cell Type RNA - Macrophages [nTPM]":"51.0","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"30.0","Single Cell Type RNA - monocytes [nTPM]":"5.2","Single Cell Type RNA - Muller glia cells [nTPM]":"1.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.4","Single Cell Type RNA - Paneth cells [nTPM]":"46.1","Single Cell Type RNA - Peritubular cells [nTPM]":"5.3","Single Cell Type RNA - Plasma cells [nTPM]":"3.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"181.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.4","Single Cell Type RNA - Spermatocytes [nTPM]":"1.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - T-cells [nTPM]":"1.7","Single Cell Type RNA - Theca cells [nTPM]":"96.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"74.3","Single Cell Type RNA - Urothelial cells [nTPM]":"1.1"},{"Gene":"PARK7","Gene synonym":["DJ-1","DJ1","GATD2"],"Ensembl":"ENSG00000116288","Gene description":"Parkinsonism associated deglycase","Uniprot":["Q99497"],"Chromosome":"1","Position":"7954291-7985505","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Autophagy","DNA damage","DNA repair","Fertilization","Inflammatory response","Stress response"],"Molecular function":["Chaperone","Hydrolase","Protease","RNA-binding"],"Disease involvement":["Disease variant","Neurodegeneration","Parkinson disease","Parkinsonism","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004190","CAB005870"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"35000000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB005870":"AB_444361","HPA004190":"AB_1079566"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Tissue RNA - adipose tissue [nTPM]":"249.4","Tissue RNA - adrenal gland [nTPM]":"373.6","Tissue RNA - amygdala [nTPM]":"283.5","Tissue RNA - appendix [nTPM]":"213.7","Tissue RNA - basal ganglia [nTPM]":"290.0","Tissue RNA - bone marrow [nTPM]":"205.0","Tissue RNA - breast [nTPM]":"235.7","Tissue RNA - cerebellum [nTPM]":"292.9","Tissue RNA - cerebral cortex [nTPM]":"403.4","Tissue RNA - cervix [nTPM]":"201.1","Tissue RNA - choroid plexus [nTPM]":"327.7","Tissue RNA - colon [nTPM]":"252.5","Tissue RNA - duodenum [nTPM]":"145.8","Tissue RNA - endometrium 1 [nTPM]":"212.2","Tissue RNA - epididymis [nTPM]":"278.0","Tissue RNA - esophagus [nTPM]":"161.0","Tissue RNA - fallopian tube [nTPM]":"203.2","Tissue RNA - gallbladder [nTPM]":"162.9","Tissue RNA - heart muscle [nTPM]":"388.0","Tissue RNA - hippocampal formation [nTPM]":"285.5","Tissue RNA - hypothalamus [nTPM]":"296.6","Tissue RNA - kidney [nTPM]":"311.0","Tissue RNA - liver [nTPM]":"397.6","Tissue RNA - lung [nTPM]":"181.6","Tissue RNA - lymph node [nTPM]":"269.2","Tissue RNA - medulla oblongata [nTPM]":"289.6","Tissue RNA - midbrain [nTPM]":"286.0","Tissue RNA - ovary [nTPM]":"234.2","Tissue RNA - pancreas [nTPM]":"308.5","Tissue RNA - parathyroid gland [nTPM]":"387.6","Tissue RNA - pituitary gland [nTPM]":"283.6","Tissue RNA - placenta [nTPM]":"174.1","Tissue RNA - pons [nTPM]":"291.7","Tissue RNA - prostate [nTPM]":"234.9","Tissue RNA - rectum [nTPM]":"194.9","Tissue RNA - retina [nTPM]":"273.8","Tissue RNA - salivary gland [nTPM]":"240.9","Tissue RNA - seminal vesicle [nTPM]":"185.6","Tissue RNA - skeletal muscle [nTPM]":"771.4","Tissue RNA - skin 1 [nTPM]":"127.1","Tissue RNA - small intestine [nTPM]":"170.5","Tissue RNA - smooth muscle [nTPM]":"199.1","Tissue RNA - spinal cord [nTPM]":"295.2","Tissue RNA - spleen [nTPM]":"188.2","Tissue RNA - stomach 1 [nTPM]":"234.2","Tissue RNA - testis [nTPM]":"139.6","Tissue RNA - thalamus [nTPM]":"288.1","Tissue RNA - thymus [nTPM]":"217.9","Tissue RNA - thyroid gland [nTPM]":"286.3","Tissue RNA - tongue [nTPM]":"541.8","Tissue RNA - tonsil [nTPM]":"249.7","Tissue RNA - urinary bladder [nTPM]":"226.5","Tissue RNA - vagina [nTPM]":"171.2","Tissue RNA - white matter [nTPM]":"299.7","Cell RNA - A-431 [nTPM]":"537.0","Cell RNA - A549 [nTPM]":"452.5","Cell RNA - AF22 [nTPM]":"467.1","Cell RNA - AN3-CA [nTPM]":"523.2","Cell RNA - ASC diff [nTPM]":"459.8","Cell RNA - ASC TERT1 [nTPM]":"442.6","Cell RNA - BEWO [nTPM]":"218.4","Cell RNA - BJ [nTPM]":"476.7","Cell RNA - BJ hTERT+ [nTPM]":"434.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"450.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"360.3","Cell RNA - CACO-2 [nTPM]":"419.9","Cell RNA - CAPAN-2 [nTPM]":"549.4","Cell RNA - Daudi [nTPM]":"633.1","Cell RNA - EFO-21 [nTPM]":"534.2","Cell RNA - fHDF\/TERT166 [nTPM]":"505.1","Cell RNA - GAMG [nTPM]":"328.6","Cell RNA - HaCaT [nTPM]":"367.1","Cell RNA - HAP1 [nTPM]":"483.2","Cell RNA - HBEC3-KT [nTPM]":"625.3","Cell RNA - HBF TERT88 [nTPM]":"579.3","Cell RNA - HDLM-2 [nTPM]":"574.5","Cell RNA - HEK 293 [nTPM]":"526.2","Cell RNA - HEL [nTPM]":"683.0","Cell RNA - HeLa [nTPM]":"678.6","Cell RNA - Hep G2 [nTPM]":"674.5","Cell RNA - HHSteC [nTPM]":"403.8","Cell RNA - HL-60 [nTPM]":"662.9","Cell RNA - HMC-1 [nTPM]":"418.6","Cell RNA - HSkMC [nTPM]":"421.3","Cell RNA - hTCEpi [nTPM]":"262.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"459.8","Cell RNA - hTERT-HME1 [nTPM]":"547.4","Cell RNA - hTERT-RPE1 [nTPM]":"359.2","Cell RNA - HUVEC TERT2 [nTPM]":"478.2","Cell RNA - JURKAT [nTPM]":"340.1","Cell RNA - K-562 [nTPM]":"676.8","Cell RNA - Karpas-707 [nTPM]":"471.7","Cell RNA - LHCN-M2 [nTPM]":"633.0","Cell RNA - MCF7 [nTPM]":"485.0","Cell RNA - MOLT-4 [nTPM]":"474.3","Cell RNA - NB-4 [nTPM]":"868.7","Cell RNA - NTERA-2 [nTPM]":"376.1","Cell RNA - OE19 [nTPM]":"653.6","Cell RNA - PC-3 [nTPM]":"465.4","Cell RNA - REH [nTPM]":"366.7","Cell RNA - RH-30 [nTPM]":"598.0","Cell RNA - RPMI-8226 [nTPM]":"888.7","Cell RNA - RPTEC TERT1 [nTPM]":"714.7","Cell RNA - RT4 [nTPM]":"269.7","Cell RNA - SCLC-21H [nTPM]":"527.7","Cell RNA - SH-SY5Y [nTPM]":"447.4","Cell RNA - SiHa [nTPM]":"470.4","Cell RNA - SK-BR-3 [nTPM]":"728.0","Cell RNA - SK-MEL-30 [nTPM]":"798.4","Cell RNA - SuSa [nTPM]":"370.1","Cell RNA - T-47d [nTPM]":"414.9","Cell RNA - THP-1 [nTPM]":"503.7","Cell RNA - TIME [nTPM]":"459.3","Cell RNA - U-138 MG [nTPM]":"412.8","Cell RNA - U-2 OS [nTPM]":"344.6","Cell RNA - U-2197 [nTPM]":"395.5","Cell RNA - U-251 MG [nTPM]":"539.5","Cell RNA - U-266\/70 [nTPM]":"452.8","Cell RNA - U-266\/84 [nTPM]":"788.4","Cell RNA - U-698 [nTPM]":"938.8","Cell RNA - U-87 MG [nTPM]":"551.5","Cell RNA - U-937 [nTPM]":"1002.9","Cell RNA - WM-115 [nTPM]":"606.4","Blood RNA - basophil [nTPM]":"298.4","Blood RNA - classical monocyte [nTPM]":"590.2","Blood RNA - eosinophil [nTPM]":"394.0","Blood RNA - gdT-cell [nTPM]":"484.7","Blood RNA - intermediate monocyte [nTPM]":"553.7","Blood RNA - MAIT T-cell [nTPM]":"459.2","Blood RNA - memory B-cell [nTPM]":"483.6","Blood RNA - memory CD4 T-cell [nTPM]":"478.2","Blood RNA - memory CD8 T-cell [nTPM]":"577.3","Blood RNA - myeloid DC [nTPM]":"717.4","Blood RNA - naive B-cell [nTPM]":"374.6","Blood RNA - naive CD4 T-cell [nTPM]":"406.8","Blood RNA - naive CD8 T-cell [nTPM]":"466.8","Blood RNA - neutrophil [nTPM]":"202.5","Blood RNA - NK-cell [nTPM]":"551.1","Blood RNA - non-classical monocyte [nTPM]":"456.9","Blood RNA - plasmacytoid DC [nTPM]":"1378.2","Blood RNA - T-reg [nTPM]":"874.4","Blood RNA - total PBMC [nTPM]":"1060.8","Brain RNA - amygdala [nTPM]":"283.5","Brain RNA - basal ganglia [nTPM]":"290.0","Brain RNA - cerebellum [nTPM]":"292.9","Brain RNA - cerebral cortex [nTPM]":"403.4","Brain RNA - hippocampal formation [nTPM]":"285.5","Brain RNA - hypothalamus [nTPM]":"296.6","Brain RNA - medulla oblongata [nTPM]":"289.6","Brain RNA - midbrain [nTPM]":"286.0","Brain RNA - pons [nTPM]":"291.7","Brain RNA - spinal cord [nTPM]":"295.2","Brain RNA - thalamus [nTPM]":"288.1","Brain RNA - white matter [nTPM]":"299.7","Single Cell Type RNA - Adipocytes [nTPM]":"243.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"131.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"157.1","Single Cell Type RNA - Astrocytes [nTPM]":"23.2","Single Cell Type RNA - B-cells [nTPM]":"211.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"208.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"402.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"677.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"200.9","Single Cell Type RNA - Bipolar cells [nTPM]":"196.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"342.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"381.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"453.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"257.4","Single Cell Type RNA - Club cells [nTPM]":"318.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"248.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"79.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"553.0","Single Cell Type RNA - dendritic cells [nTPM]":"382.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"131.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"851.0","Single Cell Type RNA - Ductal cells [nTPM]":"504.3","Single Cell Type RNA - Early spermatids [nTPM]":"32.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"272.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"263.9","Single Cell Type RNA - Endothelial cells [nTPM]":"241.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"238.0","Single Cell Type RNA - Erythroid cells [nTPM]":"177.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"478.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"612.1","Single Cell Type RNA - Fibroblasts [nTPM]":"302.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"146.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"195.9","Single Cell Type RNA - granulocytes [nTPM]":"206.5","Single Cell Type RNA - Granulosa cells [nTPM]":"291.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"183.1","Single Cell Type RNA - Hepatocytes [nTPM]":"368.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"435.1","Single Cell Type RNA - Horizontal cells [nTPM]":"186.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"279.6","Single Cell Type RNA - Ionocytes [nTPM]":"484.2","Single Cell Type RNA - Kupffer cells [nTPM]":"204.5","Single Cell Type RNA - Langerhans cells [nTPM]":"304.5","Single Cell Type RNA - Late spermatids [nTPM]":"53.6","Single Cell Type RNA - Leydig cells [nTPM]":"358.2","Single Cell Type RNA - Macrophages [nTPM]":"258.9","Single Cell Type RNA - Melanocytes [nTPM]":"359.3","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"605.4","Single Cell Type RNA - Muller glia cells [nTPM]":"816.4","Single Cell Type RNA - NK-cells [nTPM]":"327.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"36.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"378.9","Single Cell Type RNA - Paneth cells [nTPM]":"186.9","Single Cell Type RNA - Peritubular cells [nTPM]":"378.7","Single Cell Type RNA - Plasma cells [nTPM]":"269.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"523.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"227.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"941.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"327.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"235.5","Single Cell Type RNA - Sertoli cells [nTPM]":"276.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"277.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"342.6","Single Cell Type RNA - Spermatocytes [nTPM]":"288.2","Single Cell Type RNA - Spermatogonia [nTPM]":"302.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"220.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"143.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"469.6","Single Cell Type RNA - T-cells [nTPM]":"244.4","Single Cell Type RNA - Theca cells [nTPM]":"535.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"312.2","Single Cell Type RNA - Urothelial cells [nTPM]":"433.1"},{"Gene":"PARN","Gene synonym":["DAN"],"Ensembl":"ENSG00000140694","Gene description":"Poly(A)-specific ribonuclease","Uniprot":["O95453"],"Chromosome":"16","Position":"14435700-14632728","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Nonsense-mediated mRNA decay"],"Molecular function":["Exonuclease","Hydrolase","Nuclease","RNA-binding"],"Disease involvement":["Disease variant","Dyskeratosis congenita"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006314","CAB011673","HPA012010"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"CAB011673":"AB_778216","HPA006314":"AB_1079567","HPA012010":"AB_1854976"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.64e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Tissue RNA - adipose tissue [nTPM]":"16.6","Tissue RNA - adrenal gland [nTPM]":"20.2","Tissue RNA - amygdala [nTPM]":"10.8","Tissue RNA - appendix [nTPM]":"13.9","Tissue RNA - basal ganglia [nTPM]":"12.1","Tissue RNA - bone marrow [nTPM]":"9.2","Tissue RNA - breast [nTPM]":"15.9","Tissue RNA - cerebellum [nTPM]":"11.7","Tissue RNA - cerebral cortex [nTPM]":"11.4","Tissue RNA - cervix [nTPM]":"17.2","Tissue RNA - choroid plexus [nTPM]":"12.0","Tissue RNA - colon [nTPM]":"19.3","Tissue RNA - duodenum [nTPM]":"11.8","Tissue RNA - endometrium 1 [nTPM]":"19.1","Tissue RNA - epididymis [nTPM]":"24.7","Tissue RNA - esophagus [nTPM]":"15.6","Tissue RNA - fallopian tube [nTPM]":"16.0","Tissue RNA - gallbladder [nTPM]":"13.4","Tissue RNA - heart muscle [nTPM]":"14.8","Tissue RNA - hippocampal formation [nTPM]":"10.6","Tissue RNA - hypothalamus [nTPM]":"14.0","Tissue RNA - kidney [nTPM]":"12.7","Tissue RNA - liver [nTPM]":"16.4","Tissue RNA - lung [nTPM]":"14.2","Tissue RNA - lymph node [nTPM]":"21.2","Tissue RNA - medulla oblongata [nTPM]":"11.7","Tissue RNA - midbrain [nTPM]":"11.9","Tissue RNA - ovary [nTPM]":"16.4","Tissue RNA - pancreas [nTPM]":"16.5","Tissue RNA - parathyroid gland [nTPM]":"21.1","Tissue RNA - pituitary gland [nTPM]":"16.3","Tissue RNA - placenta [nTPM]":"15.6","Tissue RNA - pons [nTPM]":"11.9","Tissue RNA - prostate [nTPM]":"16.1","Tissue RNA - rectum [nTPM]":"16.8","Tissue RNA - retina [nTPM]":"7.0","Tissue RNA - salivary gland [nTPM]":"15.3","Tissue RNA - seminal vesicle [nTPM]":"17.1","Tissue RNA - skeletal muscle [nTPM]":"16.8","Tissue RNA - skin 1 [nTPM]":"17.9","Tissue RNA - small intestine [nTPM]":"16.1","Tissue RNA - smooth muscle [nTPM]":"18.0","Tissue RNA - spinal cord [nTPM]":"11.3","Tissue RNA - spleen [nTPM]":"15.7","Tissue RNA - stomach 1 [nTPM]":"16.2","Tissue RNA - testis [nTPM]":"18.1","Tissue RNA - thalamus [nTPM]":"12.6","Tissue RNA - thymus [nTPM]":"21.6","Tissue RNA - thyroid gland [nTPM]":"20.6","Tissue RNA - tongue [nTPM]":"9.7","Tissue RNA - tonsil [nTPM]":"23.4","Tissue RNA - urinary bladder [nTPM]":"19.3","Tissue RNA - vagina [nTPM]":"16.0","Tissue RNA - white matter [nTPM]":"13.5","Cell RNA - A-431 [nTPM]":"28.0","Cell RNA - A549 [nTPM]":"39.9","Cell RNA - AF22 [nTPM]":"17.6","Cell RNA - AN3-CA [nTPM]":"22.9","Cell RNA - ASC diff [nTPM]":"32.9","Cell RNA - ASC TERT1 [nTPM]":"33.2","Cell RNA - BEWO [nTPM]":"20.3","Cell RNA - BJ [nTPM]":"24.4","Cell RNA - BJ hTERT+ [nTPM]":"32.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"29.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"28.3","Cell RNA - CACO-2 [nTPM]":"21.9","Cell RNA - CAPAN-2 [nTPM]":"28.7","Cell RNA - Daudi [nTPM]":"56.2","Cell RNA - EFO-21 [nTPM]":"63.1","Cell RNA - fHDF\/TERT166 [nTPM]":"32.3","Cell RNA - GAMG [nTPM]":"25.3","Cell RNA - HaCaT [nTPM]":"30.4","Cell RNA - HAP1 [nTPM]":"46.7","Cell RNA - HBEC3-KT [nTPM]":"32.3","Cell RNA - HBF TERT88 [nTPM]":"41.0","Cell RNA - HDLM-2 [nTPM]":"42.9","Cell RNA - HEK 293 [nTPM]":"29.4","Cell RNA - HEL [nTPM]":"28.8","Cell RNA - HeLa [nTPM]":"24.2","Cell RNA - Hep G2 [nTPM]":"53.2","Cell RNA - HHSteC [nTPM]":"35.5","Cell RNA - HL-60 [nTPM]":"46.0","Cell RNA - HMC-1 [nTPM]":"36.2","Cell RNA - HSkMC [nTPM]":"32.5","Cell RNA - hTCEpi [nTPM]":"38.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.0","Cell RNA - hTERT-HME1 [nTPM]":"43.1","Cell RNA - hTERT-RPE1 [nTPM]":"25.5","Cell RNA - HUVEC TERT2 [nTPM]":"22.5","Cell RNA - JURKAT [nTPM]":"32.6","Cell RNA - K-562 [nTPM]":"28.5","Cell RNA - Karpas-707 [nTPM]":"29.9","Cell RNA - LHCN-M2 [nTPM]":"32.5","Cell RNA - MCF7 [nTPM]":"44.9","Cell RNA - MOLT-4 [nTPM]":"36.7","Cell RNA - NB-4 [nTPM]":"33.1","Cell RNA - NTERA-2 [nTPM]":"26.0","Cell RNA - OE19 [nTPM]":"28.2","Cell RNA - PC-3 [nTPM]":"16.7","Cell RNA - REH [nTPM]":"56.2","Cell RNA - RH-30 [nTPM]":"36.1","Cell RNA - RPMI-8226 [nTPM]":"57.1","Cell RNA - RPTEC TERT1 [nTPM]":"23.1","Cell RNA - RT4 [nTPM]":"17.1","Cell RNA - SCLC-21H [nTPM]":"18.7","Cell RNA - SH-SY5Y [nTPM]":"16.9","Cell RNA - SiHa [nTPM]":"53.4","Cell RNA - SK-BR-3 [nTPM]":"29.6","Cell RNA - SK-MEL-30 [nTPM]":"36.3","Cell RNA - SuSa [nTPM]":"28.6","Cell RNA - T-47d [nTPM]":"31.6","Cell RNA - THP-1 [nTPM]":"28.0","Cell RNA - TIME [nTPM]":"21.2","Cell RNA - U-138 MG [nTPM]":"31.5","Cell RNA - U-2 OS [nTPM]":"15.8","Cell RNA - U-2197 [nTPM]":"16.4","Cell RNA - U-251 MG [nTPM]":"26.9","Cell RNA - U-266\/70 [nTPM]":"32.5","Cell RNA - U-266\/84 [nTPM]":"31.0","Cell RNA - U-698 [nTPM]":"63.5","Cell RNA - U-87 MG [nTPM]":"34.6","Cell RNA - U-937 [nTPM]":"30.8","Cell RNA - WM-115 [nTPM]":"35.8","Blood RNA - basophil [nTPM]":"8.9","Blood RNA - classical monocyte [nTPM]":"8.0","Blood RNA - eosinophil [nTPM]":"15.8","Blood RNA - gdT-cell [nTPM]":"8.6","Blood RNA - intermediate monocyte [nTPM]":"13.2","Blood RNA - MAIT T-cell [nTPM]":"7.7","Blood RNA - memory B-cell [nTPM]":"16.0","Blood RNA - memory CD4 T-cell [nTPM]":"10.4","Blood RNA - memory CD8 T-cell [nTPM]":"12.4","Blood RNA - myeloid DC [nTPM]":"13.6","Blood RNA - naive B-cell [nTPM]":"9.4","Blood RNA - naive CD4 T-cell [nTPM]":"14.2","Blood RNA - naive CD8 T-cell [nTPM]":"14.4","Blood RNA - neutrophil [nTPM]":"6.2","Blood RNA - NK-cell [nTPM]":"15.0","Blood RNA - non-classical monocyte [nTPM]":"15.6","Blood RNA - plasmacytoid DC [nTPM]":"8.3","Blood RNA - T-reg [nTPM]":"19.1","Blood RNA - total PBMC [nTPM]":"7.1","Brain RNA - amygdala [nTPM]":"10.8","Brain RNA - basal ganglia [nTPM]":"12.1","Brain RNA - cerebellum [nTPM]":"11.7","Brain RNA - cerebral cortex [nTPM]":"11.4","Brain RNA - hippocampal formation [nTPM]":"10.6","Brain RNA - hypothalamus [nTPM]":"14.0","Brain RNA - medulla oblongata [nTPM]":"11.7","Brain RNA - midbrain [nTPM]":"11.9","Brain RNA - pons [nTPM]":"11.9","Brain RNA - spinal cord [nTPM]":"11.3","Brain RNA - thalamus [nTPM]":"12.6","Brain RNA - white matter [nTPM]":"13.5","Single Cell Type RNA - Adipocytes [nTPM]":"18.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"39.1","Single Cell Type RNA - Astrocytes [nTPM]":"37.9","Single Cell Type RNA - B-cells [nTPM]":"26.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.6","Single Cell Type RNA - Bipolar cells [nTPM]":"13.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"22.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"11.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"29.2","Single Cell Type RNA - dendritic cells [nTPM]":"24.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"14.2","Single Cell Type RNA - Early spermatids [nTPM]":"14.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.5","Single Cell Type RNA - Endothelial cells [nTPM]":"15.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.9","Single Cell Type RNA - Erythroid cells [nTPM]":"20.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"48.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"23.2","Single Cell Type RNA - Fibroblasts [nTPM]":"19.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.7","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"19.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"15.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.8","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"48.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.3","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"14.2","Single Cell Type RNA - Langerhans cells [nTPM]":"5.8","Single Cell Type RNA - Late spermatids [nTPM]":"6.3","Single Cell Type RNA - Leydig cells [nTPM]":"21.1","Single Cell Type RNA - Macrophages [nTPM]":"18.2","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"54.4","Single Cell Type RNA - monocytes [nTPM]":"35.8","Single Cell Type RNA - Muller glia cells [nTPM]":"10.3","Single Cell Type RNA - NK-cells [nTPM]":"52.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"38.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"72.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.2","Single Cell Type RNA - Paneth cells [nTPM]":"10.6","Single Cell Type RNA - Peritubular cells [nTPM]":"17.7","Single Cell Type RNA - Plasma cells [nTPM]":"23.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.8","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.0","Single Cell Type RNA - Spermatocytes [nTPM]":"70.5","Single Cell Type RNA - Spermatogonia [nTPM]":"70.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.4","Single Cell Type RNA - T-cells [nTPM]":"21.5","Single Cell Type RNA - Theca cells [nTPM]":"20.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.4","Single Cell Type RNA - Urothelial cells [nTPM]":"4.8"},{"Gene":"PARS2","Gene synonym":["DKFZp727A071"],"Ensembl":"ENSG00000162396","Gene description":"Prolyl-tRNA synthetase 2, mitochondrial","Uniprot":["Q7L3T8"],"Chromosome":"1","Position":"54756898-54764523","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"9.8","Early spermatids":"11.0","Spermatocytes":"10.5","Spermatogonia":"11.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028308","HPA028314","HPA028518"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoli fibrillar center","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA028308":"AB_2672553","HPA028314":"AB_10603981","HPA028518":"AB_2672653"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.26e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.34e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.24e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.3","Tissue RNA - adrenal gland [nTPM]":"2.9","Tissue RNA - amygdala [nTPM]":"2.5","Tissue RNA - appendix [nTPM]":"1.9","Tissue RNA - basal ganglia [nTPM]":"3.0","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"2.7","Tissue RNA - cerebellum [nTPM]":"2.8","Tissue RNA - cerebral cortex [nTPM]":"3.1","Tissue RNA - cervix [nTPM]":"2.7","Tissue RNA - choroid plexus [nTPM]":"3.0","Tissue RNA - colon [nTPM]":"4.0","Tissue RNA - duodenum [nTPM]":"2.7","Tissue RNA - endometrium 1 [nTPM]":"2.5","Tissue RNA - epididymis [nTPM]":"3.2","Tissue RNA - esophagus [nTPM]":"2.7","Tissue RNA - fallopian tube [nTPM]":"4.4","Tissue RNA - gallbladder [nTPM]":"1.6","Tissue RNA - heart muscle [nTPM]":"3.0","Tissue RNA - hippocampal formation [nTPM]":"2.6","Tissue RNA - hypothalamus [nTPM]":"2.6","Tissue RNA - kidney [nTPM]":"4.2","Tissue RNA - liver [nTPM]":"3.4","Tissue RNA - lung [nTPM]":"1.4","Tissue RNA - lymph node [nTPM]":"2.0","Tissue RNA - medulla oblongata [nTPM]":"2.5","Tissue RNA - midbrain [nTPM]":"2.7","Tissue RNA - ovary [nTPM]":"4.8","Tissue RNA - pancreas [nTPM]":"2.3","Tissue RNA - parathyroid gland [nTPM]":"4.7","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"2.5","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"2.3","Tissue RNA - rectum [nTPM]":"3.6","Tissue RNA - retina [nTPM]":"2.0","Tissue RNA - salivary gland [nTPM]":"3.3","Tissue RNA - seminal vesicle [nTPM]":"2.8","Tissue RNA - skeletal muscle [nTPM]":"4.4","Tissue RNA - skin 1 [nTPM]":"2.9","Tissue RNA - small intestine [nTPM]":"2.1","Tissue RNA - smooth muscle [nTPM]":"2.0","Tissue RNA - spinal cord [nTPM]":"2.7","Tissue RNA - spleen [nTPM]":"1.8","Tissue RNA - stomach 1 [nTPM]":"2.5","Tissue RNA - testis [nTPM]":"4.8","Tissue RNA - thalamus [nTPM]":"2.7","Tissue RNA - thymus [nTPM]":"2.6","Tissue RNA - thyroid gland [nTPM]":"2.9","Tissue RNA - tongue [nTPM]":"5.5","Tissue RNA - tonsil [nTPM]":"2.4","Tissue RNA - urinary bladder [nTPM]":"2.1","Tissue RNA - vagina [nTPM]":"2.0","Tissue RNA - white matter [nTPM]":"3.0","Cell RNA - A-431 [nTPM]":"4.4","Cell RNA - A549 [nTPM]":"7.2","Cell RNA - AF22 [nTPM]":"4.6","Cell RNA - AN3-CA [nTPM]":"6.0","Cell RNA - ASC diff [nTPM]":"5.5","Cell RNA - ASC TERT1 [nTPM]":"4.6","Cell RNA - BEWO [nTPM]":"10.3","Cell RNA - BJ [nTPM]":"3.7","Cell RNA - BJ hTERT+ [nTPM]":"4.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.6","Cell RNA - CACO-2 [nTPM]":"8.3","Cell RNA - CAPAN-2 [nTPM]":"2.8","Cell RNA - Daudi [nTPM]":"7.7","Cell RNA - EFO-21 [nTPM]":"5.6","Cell RNA - fHDF\/TERT166 [nTPM]":"3.3","Cell RNA - GAMG [nTPM]":"9.3","Cell RNA - HaCaT [nTPM]":"6.9","Cell RNA - HAP1 [nTPM]":"8.3","Cell RNA - HBEC3-KT [nTPM]":"5.8","Cell RNA - HBF TERT88 [nTPM]":"4.7","Cell RNA - HDLM-2 [nTPM]":"5.0","Cell RNA - HEK 293 [nTPM]":"7.5","Cell RNA - HEL [nTPM]":"7.4","Cell RNA - HeLa [nTPM]":"4.0","Cell RNA - Hep G2 [nTPM]":"6.2","Cell RNA - HHSteC [nTPM]":"8.5","Cell RNA - HL-60 [nTPM]":"4.3","Cell RNA - HMC-1 [nTPM]":"2.5","Cell RNA - HSkMC [nTPM]":"5.0","Cell RNA - hTCEpi [nTPM]":"8.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.3","Cell RNA - hTERT-HME1 [nTPM]":"7.4","Cell RNA - hTERT-RPE1 [nTPM]":"5.5","Cell RNA - HUVEC TERT2 [nTPM]":"4.8","Cell RNA - JURKAT [nTPM]":"8.4","Cell RNA - K-562 [nTPM]":"13.2","Cell RNA - Karpas-707 [nTPM]":"1.0","Cell RNA - LHCN-M2 [nTPM]":"4.9","Cell RNA - MCF7 [nTPM]":"4.6","Cell RNA - MOLT-4 [nTPM]":"6.1","Cell RNA - NB-4 [nTPM]":"5.7","Cell RNA - NTERA-2 [nTPM]":"10.6","Cell RNA - OE19 [nTPM]":"8.3","Cell RNA - PC-3 [nTPM]":"9.1","Cell RNA - REH [nTPM]":"4.6","Cell RNA - RH-30 [nTPM]":"9.0","Cell RNA - RPMI-8226 [nTPM]":"9.0","Cell RNA - RPTEC TERT1 [nTPM]":"5.4","Cell RNA - RT4 [nTPM]":"3.2","Cell RNA - SCLC-21H [nTPM]":"4.7","Cell RNA - SH-SY5Y [nTPM]":"4.8","Cell RNA - SiHa [nTPM]":"5.3","Cell RNA - SK-BR-3 [nTPM]":"6.9","Cell RNA - SK-MEL-30 [nTPM]":"9.7","Cell RNA - SuSa [nTPM]":"8.7","Cell RNA - T-47d [nTPM]":"3.9","Cell RNA - THP-1 [nTPM]":"5.5","Cell RNA - TIME [nTPM]":"2.6","Cell RNA - U-138 MG [nTPM]":"4.8","Cell RNA - U-2 OS [nTPM]":"4.9","Cell RNA - U-2197 [nTPM]":"6.8","Cell RNA - U-251 MG [nTPM]":"4.7","Cell RNA - U-266\/70 [nTPM]":"7.3","Cell RNA - U-266\/84 [nTPM]":"6.6","Cell RNA - U-698 [nTPM]":"3.0","Cell RNA - U-87 MG [nTPM]":"3.6","Cell RNA - U-937 [nTPM]":"5.1","Cell RNA - WM-115 [nTPM]":"2.8","Blood RNA - basophil [nTPM]":"1.2","Blood RNA - classical monocyte [nTPM]":"5.3","Blood RNA - eosinophil [nTPM]":"4.5","Blood RNA - gdT-cell [nTPM]":"4.8","Blood RNA - intermediate monocyte [nTPM]":"7.7","Blood RNA - MAIT T-cell [nTPM]":"5.9","Blood RNA - memory B-cell [nTPM]":"4.9","Blood RNA - memory CD4 T-cell [nTPM]":"5.3","Blood RNA - memory CD8 T-cell [nTPM]":"5.3","Blood RNA - myeloid DC [nTPM]":"7.3","Blood RNA - naive B-cell [nTPM]":"5.5","Blood RNA - naive CD4 T-cell [nTPM]":"7.8","Blood RNA - naive CD8 T-cell [nTPM]":"5.3","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"7.4","Blood RNA - non-classical monocyte [nTPM]":"10.7","Blood RNA - plasmacytoid DC [nTPM]":"5.9","Blood RNA - T-reg [nTPM]":"8.2","Blood RNA - total PBMC [nTPM]":"5.0","Brain RNA - amygdala [nTPM]":"2.5","Brain RNA - basal ganglia [nTPM]":"3.0","Brain RNA - cerebellum [nTPM]":"2.8","Brain RNA - cerebral cortex [nTPM]":"3.1","Brain RNA - hippocampal formation [nTPM]":"2.6","Brain RNA - hypothalamus [nTPM]":"2.6","Brain RNA - medulla oblongata [nTPM]":"2.5","Brain RNA - midbrain [nTPM]":"2.7","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"2.7","Brain RNA - thalamus [nTPM]":"2.7","Brain RNA - white matter [nTPM]":"3.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"2.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"1.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"4.5","Single Cell Type RNA - Early spermatids [nTPM]":"11.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.9","Single Cell Type RNA - Fibroblasts [nTPM]":"1.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"2.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.1","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.2","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"6.8","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"1.1","Single Cell Type RNA - Muller glia cells [nTPM]":"3.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.9","Single Cell Type RNA - Paneth cells [nTPM]":"1.5","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.1","Single Cell Type RNA - Spermatocytes [nTPM]":"10.5","Single Cell Type RNA - Spermatogonia [nTPM]":"11.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.3","Single Cell Type RNA - T-cells [nTPM]":"0.7","Single Cell Type RNA - Theca cells [nTPM]":"5.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"PC","Gene synonym":["PCB"],"Ensembl":"ENSG00000173599","Gene description":"Pyruvate carboxylase","Uniprot":["P11498"],"Chromosome":"11","Position":"66848417-66958386","Protein class":["Citric acid cycle related proteins","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Gluconeogenesis","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Ligase","Multifunctional enzyme"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"148.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"201.9","Late spermatids":"53.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"37.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"57.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033742","HPA043922","HPA058765"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"200000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB033742":"AB_2283532","HPA043922":"AB_2678732","HPA058765":"AB_2683812"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.24e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.86e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.22e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.15e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Tissue RNA - adipose tissue [nTPM]":"60.9","Tissue RNA - adrenal gland [nTPM]":"23.7","Tissue RNA - amygdala [nTPM]":"35.7","Tissue RNA - appendix [nTPM]":"2.9","Tissue RNA - basal ganglia [nTPM]":"35.5","Tissue RNA - bone marrow [nTPM]":"3.5","Tissue RNA - breast [nTPM]":"28.4","Tissue RNA - cerebellum [nTPM]":"36.6","Tissue RNA - cerebral cortex [nTPM]":"35.8","Tissue RNA - cervix [nTPM]":"3.7","Tissue RNA - choroid plexus [nTPM]":"17.5","Tissue RNA - colon [nTPM]":"4.7","Tissue RNA - duodenum [nTPM]":"6.5","Tissue RNA - endometrium 1 [nTPM]":"3.8","Tissue RNA - epididymis [nTPM]":"1.8","Tissue RNA - esophagus [nTPM]":"9.3","Tissue RNA - fallopian tube [nTPM]":"3.2","Tissue RNA - gallbladder [nTPM]":"2.8","Tissue RNA - heart muscle [nTPM]":"4.3","Tissue RNA - hippocampal formation [nTPM]":"32.4","Tissue RNA - hypothalamus [nTPM]":"41.0","Tissue RNA - kidney [nTPM]":"23.3","Tissue RNA - liver [nTPM]":"148.0","Tissue RNA - lung [nTPM]":"2.6","Tissue RNA - lymph node [nTPM]":"1.3","Tissue RNA - medulla oblongata [nTPM]":"43.4","Tissue RNA - midbrain [nTPM]":"40.1","Tissue RNA - ovary [nTPM]":"5.1","Tissue RNA - pancreas [nTPM]":"4.9","Tissue RNA - parathyroid gland [nTPM]":"18.2","Tissue RNA - pituitary gland [nTPM]":"8.6","Tissue RNA - placenta [nTPM]":"4.4","Tissue RNA - pons [nTPM]":"37.6","Tissue RNA - prostate [nTPM]":"7.2","Tissue RNA - rectum [nTPM]":"2.8","Tissue RNA - retina [nTPM]":"2.4","Tissue RNA - salivary gland [nTPM]":"35.3","Tissue RNA - seminal vesicle [nTPM]":"9.3","Tissue RNA - skeletal muscle [nTPM]":"12.1","Tissue RNA - skin 1 [nTPM]":"4.7","Tissue RNA - small intestine [nTPM]":"7.7","Tissue RNA - smooth muscle [nTPM]":"1.4","Tissue RNA - spinal cord [nTPM]":"37.8","Tissue RNA - spleen [nTPM]":"1.5","Tissue RNA - stomach 1 [nTPM]":"9.1","Tissue RNA - testis [nTPM]":"10.7","Tissue RNA - thalamus [nTPM]":"49.0","Tissue RNA - thymus [nTPM]":"2.0","Tissue RNA - thyroid gland [nTPM]":"4.6","Tissue RNA - tongue [nTPM]":"6.6","Tissue RNA - tonsil [nTPM]":"2.0","Tissue RNA - urinary bladder [nTPM]":"2.9","Tissue RNA - vagina [nTPM]":"4.4","Tissue RNA - white matter [nTPM]":"37.0","Cell RNA - A-431 [nTPM]":"6.1","Cell RNA - A549 [nTPM]":"19.3","Cell RNA - AF22 [nTPM]":"6.5","Cell RNA - AN3-CA [nTPM]":"17.2","Cell RNA - ASC diff [nTPM]":"25.4","Cell RNA - ASC TERT1 [nTPM]":"8.9","Cell RNA - BEWO [nTPM]":"6.6","Cell RNA - BJ [nTPM]":"3.4","Cell RNA - BJ hTERT+ [nTPM]":"15.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.5","Cell RNA - CACO-2 [nTPM]":"8.8","Cell RNA - CAPAN-2 [nTPM]":"6.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"7.4","Cell RNA - fHDF\/TERT166 [nTPM]":"6.0","Cell RNA - GAMG [nTPM]":"9.6","Cell RNA - HaCaT [nTPM]":"6.8","Cell RNA - HAP1 [nTPM]":"7.7","Cell RNA - HBEC3-KT [nTPM]":"39.5","Cell RNA - HBF TERT88 [nTPM]":"1.5","Cell RNA - HDLM-2 [nTPM]":"2.8","Cell RNA - HEK 293 [nTPM]":"11.0","Cell RNA - HEL [nTPM]":"10.3","Cell RNA - HeLa [nTPM]":"57.4","Cell RNA - Hep G2 [nTPM]":"41.2","Cell RNA - HHSteC [nTPM]":"21.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"10.8","Cell RNA - HSkMC [nTPM]":"40.2","Cell RNA - hTCEpi [nTPM]":"10.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.8","Cell RNA - hTERT-HME1 [nTPM]":"12.4","Cell RNA - hTERT-RPE1 [nTPM]":"4.4","Cell RNA - HUVEC TERT2 [nTPM]":"5.7","Cell RNA - JURKAT [nTPM]":"14.3","Cell RNA - K-562 [nTPM]":"17.4","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"2.1","Cell RNA - MCF7 [nTPM]":"44.6","Cell RNA - MOLT-4 [nTPM]":"9.2","Cell RNA - NB-4 [nTPM]":"4.6","Cell RNA - NTERA-2 [nTPM]":"12.0","Cell RNA - OE19 [nTPM]":"15.1","Cell RNA - PC-3 [nTPM]":"16.2","Cell RNA - REH [nTPM]":"8.3","Cell RNA - RH-30 [nTPM]":"13.0","Cell RNA - RPMI-8226 [nTPM]":"3.2","Cell RNA - RPTEC TERT1 [nTPM]":"5.7","Cell RNA - RT4 [nTPM]":"1.9","Cell RNA - SCLC-21H [nTPM]":"15.2","Cell RNA - SH-SY5Y [nTPM]":"21.0","Cell RNA - SiHa [nTPM]":"33.6","Cell RNA - SK-BR-3 [nTPM]":"18.0","Cell RNA - SK-MEL-30 [nTPM]":"15.5","Cell RNA - SuSa [nTPM]":"4.8","Cell RNA - T-47d [nTPM]":"14.6","Cell RNA - THP-1 [nTPM]":"2.7","Cell RNA - TIME [nTPM]":"6.3","Cell RNA - U-138 MG [nTPM]":"7.8","Cell RNA - U-2 OS [nTPM]":"6.6","Cell RNA - U-2197 [nTPM]":"8.8","Cell RNA - U-251 MG [nTPM]":"4.7","Cell RNA - U-266\/70 [nTPM]":"3.5","Cell RNA - U-266\/84 [nTPM]":"4.8","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"7.7","Cell RNA - U-937 [nTPM]":"5.7","Cell RNA - WM-115 [nTPM]":"6.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.9","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.9","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.5","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"35.7","Brain RNA - basal ganglia [nTPM]":"35.5","Brain RNA - cerebellum [nTPM]":"36.6","Brain RNA - cerebral cortex [nTPM]":"35.8","Brain RNA - hippocampal formation [nTPM]":"32.4","Brain RNA - hypothalamus [nTPM]":"41.0","Brain RNA - medulla oblongata [nTPM]":"43.4","Brain RNA - midbrain [nTPM]":"40.1","Brain RNA - pons [nTPM]":"37.6","Brain RNA - spinal cord [nTPM]":"37.8","Brain RNA - thalamus [nTPM]":"49.0","Brain RNA - white matter [nTPM]":"37.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.0","Single Cell Type RNA - Astrocytes [nTPM]":"26.4","Single Cell Type RNA - B-cells [nTPM]":"1.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"5.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"3.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"17.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"27.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.1","Single Cell Type RNA - Early spermatids [nTPM]":"18.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.0","Single Cell Type RNA - Erythroid cells [nTPM]":"28.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.2","Single Cell Type RNA - Fibroblasts [nTPM]":"3.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.0","Single Cell Type RNA - granulocytes [nTPM]":"8.9","Single Cell Type RNA - Granulosa cells [nTPM]":"16.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.6","Single Cell Type RNA - Hepatocytes [nTPM]":"201.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"7.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.8","Single Cell Type RNA - Late spermatids [nTPM]":"53.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"1.8","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"18.9","Single Cell Type RNA - Muller glia cells [nTPM]":"9.4","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.3","Single Cell Type RNA - Paneth cells [nTPM]":"8.5","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"39.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.2","Single Cell Type RNA - Spermatocytes [nTPM]":"11.2","Single Cell Type RNA - Spermatogonia [nTPM]":"4.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"25.4","Single Cell Type RNA - T-cells [nTPM]":"1.2","Single Cell Type RNA - Theca cells [nTPM]":"6.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.4","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"PCBD1","Gene synonym":["DCOH","PCBD","PCD"],"Ensembl":"ENSG00000166228","Gene description":"Pterin-4 alpha-carbinolamine dehydratase 1","Uniprot":["P61457"],"Chromosome":"10","Position":"70882280-70888565","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Tetrahydrobiopterin biosynthesis","Transcription","Transcription regulation"],"Molecular function":["Activator","Lyase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"429.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"453.9","Hepatocytes":"603.7","Proximal tubular cells":"877.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"527.8","Hep G2":"527.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037575","HPA061723"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA037575":"AB_10671761","HPA061723":"AB_2684594"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-3"},"Tissue RNA - adipose tissue [nTPM]":"77.3","Tissue RNA - adrenal gland [nTPM]":"102.9","Tissue RNA - amygdala [nTPM]":"115.0","Tissue RNA - appendix [nTPM]":"31.0","Tissue RNA - basal ganglia [nTPM]":"111.8","Tissue RNA - bone marrow [nTPM]":"21.8","Tissue RNA - breast [nTPM]":"67.9","Tissue RNA - cerebellum [nTPM]":"111.9","Tissue RNA - cerebral cortex [nTPM]":"140.7","Tissue RNA - cervix [nTPM]":"58.0","Tissue RNA - choroid plexus [nTPM]":"114.1","Tissue RNA - colon [nTPM]":"83.9","Tissue RNA - duodenum [nTPM]":"54.4","Tissue RNA - endometrium 1 [nTPM]":"48.2","Tissue RNA - epididymis [nTPM]":"91.2","Tissue RNA - esophagus [nTPM]":"54.3","Tissue RNA - fallopian tube [nTPM]":"111.5","Tissue RNA - gallbladder [nTPM]":"47.4","Tissue RNA - heart muscle [nTPM]":"152.3","Tissue RNA - hippocampal formation [nTPM]":"109.3","Tissue RNA - hypothalamus [nTPM]":"136.9","Tissue RNA - kidney [nTPM]":"165.1","Tissue RNA - liver [nTPM]":"429.5","Tissue RNA - lung [nTPM]":"57.9","Tissue RNA - lymph node [nTPM]":"31.1","Tissue RNA - medulla oblongata [nTPM]":"125.4","Tissue RNA - midbrain [nTPM]":"138.5","Tissue RNA - ovary [nTPM]":"64.2","Tissue RNA - pancreas [nTPM]":"174.9","Tissue RNA - parathyroid gland [nTPM]":"135.1","Tissue RNA - pituitary gland [nTPM]":"61.5","Tissue RNA - placenta [nTPM]":"33.4","Tissue RNA - pons [nTPM]":"139.4","Tissue RNA - prostate [nTPM]":"73.8","Tissue RNA - rectum [nTPM]":"88.3","Tissue RNA - retina [nTPM]":"48.6","Tissue RNA - salivary gland [nTPM]":"49.9","Tissue RNA - seminal vesicle [nTPM]":"78.4","Tissue RNA - skeletal muscle [nTPM]":"109.7","Tissue RNA - skin 1 [nTPM]":"25.7","Tissue RNA - small intestine [nTPM]":"64.0","Tissue RNA - smooth muscle [nTPM]":"75.6","Tissue RNA - spinal cord [nTPM]":"119.7","Tissue RNA - spleen [nTPM]":"25.6","Tissue RNA - stomach 1 [nTPM]":"84.8","Tissue RNA - testis [nTPM]":"20.0","Tissue RNA - thalamus [nTPM]":"131.8","Tissue RNA - thymus [nTPM]":"25.8","Tissue RNA - thyroid gland [nTPM]":"86.3","Tissue RNA - tongue [nTPM]":"109.1","Tissue RNA - tonsil [nTPM]":"35.8","Tissue RNA - urinary bladder [nTPM]":"69.3","Tissue RNA - vagina [nTPM]":"39.2","Tissue RNA - white matter [nTPM]":"118.9","Cell RNA - A-431 [nTPM]":"158.3","Cell RNA - A549 [nTPM]":"374.3","Cell RNA - AF22 [nTPM]":"21.4","Cell RNA - AN3-CA [nTPM]":"223.8","Cell RNA - ASC diff [nTPM]":"80.9","Cell RNA - ASC TERT1 [nTPM]":"76.0","Cell RNA - BEWO [nTPM]":"29.4","Cell RNA - BJ [nTPM]":"50.0","Cell RNA - BJ hTERT+ [nTPM]":"84.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"77.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"61.6","Cell RNA - CACO-2 [nTPM]":"527.8","Cell RNA - CAPAN-2 [nTPM]":"270.3","Cell RNA - Daudi [nTPM]":"32.2","Cell RNA - EFO-21 [nTPM]":"141.4","Cell RNA - fHDF\/TERT166 [nTPM]":"56.3","Cell RNA - GAMG [nTPM]":"57.9","Cell RNA - HaCaT [nTPM]":"101.7","Cell RNA - HAP1 [nTPM]":"138.9","Cell RNA - HBEC3-KT [nTPM]":"81.3","Cell RNA - HBF TERT88 [nTPM]":"53.2","Cell RNA - HDLM-2 [nTPM]":"86.2","Cell RNA - HEK 293 [nTPM]":"251.9","Cell RNA - HEL [nTPM]":"28.6","Cell RNA - HeLa [nTPM]":"57.5","Cell RNA - Hep G2 [nTPM]":"527.1","Cell RNA - HHSteC [nTPM]":"84.9","Cell RNA - HL-60 [nTPM]":"28.5","Cell RNA - HMC-1 [nTPM]":"99.2","Cell RNA - HSkMC [nTPM]":"74.1","Cell RNA - hTCEpi [nTPM]":"88.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"76.5","Cell RNA - hTERT-HME1 [nTPM]":"35.8","Cell RNA - hTERT-RPE1 [nTPM]":"114.1","Cell RNA - HUVEC TERT2 [nTPM]":"212.3","Cell RNA - JURKAT [nTPM]":"19.9","Cell RNA - K-562 [nTPM]":"57.1","Cell RNA - Karpas-707 [nTPM]":"2.8","Cell RNA - LHCN-M2 [nTPM]":"55.2","Cell RNA - MCF7 [nTPM]":"270.2","Cell RNA - MOLT-4 [nTPM]":"3.5","Cell RNA - NB-4 [nTPM]":"94.7","Cell RNA - NTERA-2 [nTPM]":"30.1","Cell RNA - OE19 [nTPM]":"420.5","Cell RNA - PC-3 [nTPM]":"346.0","Cell RNA - REH [nTPM]":"15.1","Cell RNA - RH-30 [nTPM]":"29.7","Cell RNA - RPMI-8226 [nTPM]":"103.6","Cell RNA - RPTEC TERT1 [nTPM]":"328.6","Cell RNA - RT4 [nTPM]":"164.7","Cell RNA - SCLC-21H [nTPM]":"94.0","Cell RNA - SH-SY5Y [nTPM]":"158.8","Cell RNA - SiHa [nTPM]":"41.5","Cell RNA - SK-BR-3 [nTPM]":"277.1","Cell RNA - SK-MEL-30 [nTPM]":"111.5","Cell RNA - SuSa [nTPM]":"59.9","Cell RNA - T-47d [nTPM]":"81.1","Cell RNA - THP-1 [nTPM]":"53.8","Cell RNA - TIME [nTPM]":"86.2","Cell RNA - U-138 MG [nTPM]":"12.7","Cell RNA - U-2 OS [nTPM]":"102.9","Cell RNA - U-2197 [nTPM]":"18.9","Cell RNA - U-251 MG [nTPM]":"123.8","Cell RNA - U-266\/70 [nTPM]":"1.1","Cell RNA - U-266\/84 [nTPM]":"6.7","Cell RNA - U-698 [nTPM]":"1.1","Cell RNA - U-87 MG [nTPM]":"68.3","Cell RNA - U-937 [nTPM]":"93.1","Cell RNA - WM-115 [nTPM]":"19.5","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"24.8","Blood RNA - eosinophil [nTPM]":"8.7","Blood RNA - gdT-cell [nTPM]":"19.6","Blood RNA - intermediate monocyte [nTPM]":"47.1","Blood RNA - MAIT T-cell [nTPM]":"15.3","Blood RNA - memory B-cell [nTPM]":"25.7","Blood RNA - memory CD4 T-cell [nTPM]":"25.8","Blood RNA - memory CD8 T-cell [nTPM]":"28.3","Blood RNA - myeloid DC [nTPM]":"49.6","Blood RNA - naive B-cell [nTPM]":"10.9","Blood RNA - naive CD4 T-cell [nTPM]":"8.4","Blood RNA - naive CD8 T-cell [nTPM]":"17.1","Blood RNA - neutrophil [nTPM]":"1.6","Blood RNA - NK-cell [nTPM]":"19.6","Blood RNA - non-classical monocyte [nTPM]":"34.4","Blood RNA - plasmacytoid DC [nTPM]":"35.8","Blood RNA - T-reg [nTPM]":"41.1","Blood RNA - total PBMC [nTPM]":"18.7","Brain RNA - amygdala [nTPM]":"115.0","Brain RNA - basal ganglia [nTPM]":"111.8","Brain RNA - cerebellum [nTPM]":"111.9","Brain RNA - cerebral cortex [nTPM]":"140.7","Brain RNA - hippocampal formation [nTPM]":"109.3","Brain RNA - hypothalamus [nTPM]":"136.9","Brain RNA - medulla oblongata [nTPM]":"125.4","Brain RNA - midbrain [nTPM]":"138.5","Brain RNA - pons [nTPM]":"139.4","Brain RNA - spinal cord [nTPM]":"119.7","Brain RNA - thalamus [nTPM]":"131.8","Brain RNA - white matter [nTPM]":"118.9","Single Cell Type RNA - Adipocytes [nTPM]":"25.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"91.5","Single Cell Type RNA - Astrocytes [nTPM]":"8.5","Single Cell Type RNA - B-cells [nTPM]":"25.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"49.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"169.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"88.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"103.0","Single Cell Type RNA - Bipolar cells [nTPM]":"39.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"197.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"249.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"151.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"138.7","Single Cell Type RNA - Club cells [nTPM]":"86.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"187.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"124.6","Single Cell Type RNA - dendritic cells [nTPM]":"18.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"113.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"453.9","Single Cell Type RNA - Ductal cells [nTPM]":"185.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"138.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"49.3","Single Cell Type RNA - Endothelial cells [nTPM]":"40.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"176.4","Single Cell Type RNA - Erythroid cells [nTPM]":"36.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"169.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"81.6","Single Cell Type RNA - Fibroblasts [nTPM]":"82.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"86.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"175.3","Single Cell Type RNA - granulocytes [nTPM]":"31.1","Single Cell Type RNA - Granulosa cells [nTPM]":"64.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"37.9","Single Cell Type RNA - Hepatocytes [nTPM]":"603.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"180.3","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"313.3","Single Cell Type RNA - Ionocytes [nTPM]":"65.1","Single Cell Type RNA - Kupffer cells [nTPM]":"79.9","Single Cell Type RNA - Langerhans cells [nTPM]":"55.7","Single Cell Type RNA - Late spermatids [nTPM]":"11.2","Single Cell Type RNA - Leydig cells [nTPM]":"67.4","Single Cell Type RNA - Macrophages [nTPM]":"73.1","Single Cell Type RNA - Melanocytes [nTPM]":"78.2","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"68.0","Single Cell Type RNA - Muller glia cells [nTPM]":"153.0","Single Cell Type RNA - NK-cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"154.8","Single Cell Type RNA - Paneth cells [nTPM]":"164.7","Single Cell Type RNA - Peritubular cells [nTPM]":"95.5","Single Cell Type RNA - Plasma cells [nTPM]":"35.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"212.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"232.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"877.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"78.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"33.2","Single Cell Type RNA - Sertoli cells [nTPM]":"85.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"57.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"63.3","Single Cell Type RNA - Spermatocytes [nTPM]":"4.4","Single Cell Type RNA - Spermatogonia [nTPM]":"12.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"147.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"45.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"77.6","Single Cell Type RNA - T-cells [nTPM]":"32.6","Single Cell Type RNA - Theca cells [nTPM]":"95.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"230.2","Single Cell Type RNA - Urothelial cells [nTPM]":"187.5"},{"Gene":"PCCA","Gene synonym":[],"Ensembl":"ENSG00000175198","Gene description":"Propionyl-CoA carboxylase subunit alpha","Uniprot":["P05165"],"Chromosome":"13","Position":"100089015-100530437","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Ligase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"218.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"152.8","Excitatory neurons":"152.8","Inhibitory neurons":"166.5","Microglial cells":"217.4","Oligodendrocyte precursor cells":"200.6","Oligodendrocytes":"182.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RPTEC TERT1":"167.0","SCLC-21H":"91.1","U-937":"131.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041716","HPA047792"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"290000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA041716":"AB_2677635","HPA047792":"AB_2680156"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.32e-2"},"Tissue RNA - adipose tissue [nTPM]":"35.4","Tissue RNA - adrenal gland [nTPM]":"56.3","Tissue RNA - amygdala [nTPM]":"29.0","Tissue RNA - appendix [nTPM]":"12.4","Tissue RNA - basal ganglia [nTPM]":"29.8","Tissue RNA - bone marrow [nTPM]":"6.2","Tissue RNA - breast [nTPM]":"25.8","Tissue RNA - cerebellum [nTPM]":"55.5","Tissue RNA - cerebral cortex [nTPM]":"34.6","Tissue RNA - cervix [nTPM]":"22.3","Tissue RNA - choroid plexus [nTPM]":"44.4","Tissue RNA - colon [nTPM]":"37.5","Tissue RNA - duodenum [nTPM]":"13.2","Tissue RNA - endometrium 1 [nTPM]":"14.9","Tissue RNA - epididymis [nTPM]":"218.2","Tissue RNA - esophagus [nTPM]":"19.4","Tissue RNA - fallopian tube [nTPM]":"17.4","Tissue RNA - gallbladder [nTPM]":"11.6","Tissue RNA - heart muscle [nTPM]":"35.4","Tissue RNA - hippocampal formation [nTPM]":"28.6","Tissue RNA - hypothalamus [nTPM]":"26.3","Tissue RNA - kidney [nTPM]":"111.7","Tissue RNA - liver [nTPM]":"104.3","Tissue RNA - lung [nTPM]":"12.0","Tissue RNA - lymph node [nTPM]":"8.0","Tissue RNA - medulla oblongata [nTPM]":"28.9","Tissue RNA - midbrain [nTPM]":"27.4","Tissue RNA - ovary [nTPM]":"19.9","Tissue RNA - pancreas [nTPM]":"27.6","Tissue RNA - parathyroid gland [nTPM]":"25.7","Tissue RNA - pituitary gland [nTPM]":"12.3","Tissue RNA - placenta [nTPM]":"21.3","Tissue RNA - pons [nTPM]":"31.1","Tissue RNA - prostate [nTPM]":"25.9","Tissue RNA - rectum [nTPM]":"27.6","Tissue RNA - retina [nTPM]":"25.2","Tissue RNA - salivary gland [nTPM]":"26.9","Tissue RNA - seminal vesicle [nTPM]":"16.9","Tissue RNA - skeletal muscle [nTPM]":"17.6","Tissue RNA - skin 1 [nTPM]":"18.6","Tissue RNA - small intestine [nTPM]":"18.0","Tissue RNA - smooth muscle [nTPM]":"13.7","Tissue RNA - spinal cord [nTPM]":"30.3","Tissue RNA - spleen [nTPM]":"17.2","Tissue RNA - stomach 1 [nTPM]":"40.9","Tissue RNA - testis [nTPM]":"9.2","Tissue RNA - thalamus [nTPM]":"33.9","Tissue RNA - thymus [nTPM]":"11.4","Tissue RNA - thyroid gland [nTPM]":"20.4","Tissue RNA - tongue [nTPM]":"27.2","Tissue RNA - tonsil [nTPM]":"6.4","Tissue RNA - urinary bladder [nTPM]":"21.3","Tissue RNA - vagina [nTPM]":"17.5","Tissue RNA - white matter [nTPM]":"38.7","Cell RNA - A-431 [nTPM]":"10.6","Cell RNA - A549 [nTPM]":"18.5","Cell RNA - AF22 [nTPM]":"29.8","Cell RNA - AN3-CA [nTPM]":"9.9","Cell RNA - ASC diff [nTPM]":"27.9","Cell RNA - ASC TERT1 [nTPM]":"24.2","Cell RNA - BEWO [nTPM]":"16.6","Cell RNA - BJ [nTPM]":"10.2","Cell RNA - BJ hTERT+ [nTPM]":"15.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.0","Cell RNA - CACO-2 [nTPM]":"23.0","Cell RNA - CAPAN-2 [nTPM]":"13.9","Cell RNA - Daudi [nTPM]":"0.8","Cell RNA - EFO-21 [nTPM]":"15.2","Cell RNA - fHDF\/TERT166 [nTPM]":"10.1","Cell RNA - GAMG [nTPM]":"12.0","Cell RNA - HaCaT [nTPM]":"11.8","Cell RNA - HAP1 [nTPM]":"9.1","Cell RNA - HBEC3-KT [nTPM]":"14.1","Cell RNA - HBF TERT88 [nTPM]":"15.6","Cell RNA - HDLM-2 [nTPM]":"17.5","Cell RNA - HEK 293 [nTPM]":"10.1","Cell RNA - HEL [nTPM]":"24.6","Cell RNA - HeLa [nTPM]":"12.7","Cell RNA - Hep G2 [nTPM]":"49.7","Cell RNA - HHSteC [nTPM]":"15.4","Cell RNA - HL-60 [nTPM]":"1.2","Cell RNA - HMC-1 [nTPM]":"11.3","Cell RNA - HSkMC [nTPM]":"22.4","Cell RNA - hTCEpi [nTPM]":"15.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.8","Cell RNA - hTERT-HME1 [nTPM]":"14.6","Cell RNA - hTERT-RPE1 [nTPM]":"23.0","Cell RNA - HUVEC TERT2 [nTPM]":"19.6","Cell RNA - JURKAT [nTPM]":"13.0","Cell RNA - K-562 [nTPM]":"9.8","Cell RNA - Karpas-707 [nTPM]":"13.4","Cell RNA - LHCN-M2 [nTPM]":"17.1","Cell RNA - MCF7 [nTPM]":"11.6","Cell RNA - MOLT-4 [nTPM]":"2.6","Cell RNA - NB-4 [nTPM]":"54.8","Cell RNA - NTERA-2 [nTPM]":"18.6","Cell RNA - OE19 [nTPM]":"37.2","Cell RNA - PC-3 [nTPM]":"8.1","Cell RNA - REH [nTPM]":"21.4","Cell RNA - RH-30 [nTPM]":"12.9","Cell RNA - RPMI-8226 [nTPM]":"17.3","Cell RNA - RPTEC TERT1 [nTPM]":"167.0","Cell RNA - RT4 [nTPM]":"20.5","Cell RNA - SCLC-21H [nTPM]":"91.1","Cell RNA - SH-SY5Y [nTPM]":"10.9","Cell RNA - SiHa [nTPM]":"7.0","Cell RNA - SK-BR-3 [nTPM]":"38.4","Cell RNA - SK-MEL-30 [nTPM]":"17.9","Cell RNA - SuSa [nTPM]":"31.9","Cell RNA - T-47d [nTPM]":"27.9","Cell RNA - THP-1 [nTPM]":"43.1","Cell RNA - TIME [nTPM]":"14.3","Cell RNA - U-138 MG [nTPM]":"9.6","Cell RNA - U-2 OS [nTPM]":"8.0","Cell RNA - U-2197 [nTPM]":"6.7","Cell RNA - U-251 MG [nTPM]":"7.3","Cell RNA - U-266\/70 [nTPM]":"13.1","Cell RNA - U-266\/84 [nTPM]":"12.9","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"18.4","Cell RNA - U-937 [nTPM]":"131.6","Cell RNA - WM-115 [nTPM]":"6.9","Blood RNA - basophil [nTPM]":"1.6","Blood RNA - classical monocyte [nTPM]":"9.1","Blood RNA - eosinophil [nTPM]":"1.7","Blood RNA - gdT-cell [nTPM]":"4.5","Blood RNA - intermediate monocyte [nTPM]":"11.2","Blood RNA - MAIT T-cell [nTPM]":"5.9","Blood RNA - memory B-cell [nTPM]":"3.6","Blood RNA - memory CD4 T-cell [nTPM]":"2.8","Blood RNA - memory CD8 T-cell [nTPM]":"4.2","Blood RNA - myeloid DC [nTPM]":"13.5","Blood RNA - naive B-cell [nTPM]":"2.3","Blood RNA - naive CD4 T-cell [nTPM]":"3.9","Blood RNA - naive CD8 T-cell [nTPM]":"4.9","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"8.7","Blood RNA - non-classical monocyte [nTPM]":"12.3","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"6.5","Blood RNA - total PBMC [nTPM]":"5.2","Brain RNA - amygdala [nTPM]":"29.0","Brain RNA - basal ganglia [nTPM]":"29.8","Brain RNA - cerebellum [nTPM]":"55.5","Brain RNA - cerebral cortex [nTPM]":"34.6","Brain RNA - hippocampal formation [nTPM]":"28.6","Brain RNA - hypothalamus [nTPM]":"26.3","Brain RNA - medulla oblongata [nTPM]":"28.9","Brain RNA - midbrain [nTPM]":"27.4","Brain RNA - pons [nTPM]":"31.1","Brain RNA - spinal cord [nTPM]":"30.3","Brain RNA - thalamus [nTPM]":"33.9","Brain RNA - white matter [nTPM]":"38.7","Single Cell Type RNA - Adipocytes [nTPM]":"11.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.7","Single Cell Type RNA - Astrocytes [nTPM]":"152.8","Single Cell Type RNA - B-cells [nTPM]":"6.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"29.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"15.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"52.9","Single Cell Type RNA - Club cells [nTPM]":"14.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.7","Single Cell Type RNA - dendritic cells [nTPM]":"4.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"20.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"99.7","Single Cell Type RNA - Ductal cells [nTPM]":"19.7","Single Cell Type RNA - Early spermatids [nTPM]":"17.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"76.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.4","Single Cell Type RNA - Endothelial cells [nTPM]":"12.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"3.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"152.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.9","Single Cell Type RNA - Fibroblasts [nTPM]":"12.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"72.9","Single Cell Type RNA - granulocytes [nTPM]":"14.0","Single Cell Type RNA - Granulosa cells [nTPM]":"20.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.1","Single Cell Type RNA - Hepatocytes [nTPM]":"48.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.8","Single Cell Type RNA - Horizontal cells [nTPM]":"28.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"166.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.4","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"14.2","Single Cell Type RNA - Langerhans cells [nTPM]":"2.2","Single Cell Type RNA - Late spermatids [nTPM]":"12.0","Single Cell Type RNA - Leydig cells [nTPM]":"8.7","Single Cell Type RNA - Macrophages [nTPM]":"8.2","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"217.4","Single Cell Type RNA - monocytes [nTPM]":"6.0","Single Cell Type RNA - Muller glia cells [nTPM]":"11.5","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"200.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"182.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.8","Single Cell Type RNA - Paneth cells [nTPM]":"17.5","Single Cell Type RNA - Peritubular cells [nTPM]":"13.5","Single Cell Type RNA - Plasma cells [nTPM]":"9.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"86.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"31.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.1","Single Cell Type RNA - Spermatocytes [nTPM]":"7.2","Single Cell Type RNA - Spermatogonia [nTPM]":"6.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"30.2","Single Cell Type RNA - T-cells [nTPM]":"6.4","Single Cell Type RNA - Theca cells [nTPM]":"17.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"27.6","Single Cell Type RNA - Urothelial cells [nTPM]":"19.2"},{"Gene":"PCCB","Gene synonym":[],"Ensembl":"ENSG00000114054","Gene description":"Propionyl-CoA carboxylase subunit beta","Uniprot":["P05166"],"Chromosome":"3","Position":"136250340-136337896","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Ligase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"202.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"316.7","Late spermatids":"159.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036939","HPA036940"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"120000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036939":"AB_10671366","HPA036940":"AB_10669779"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.88e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.47e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-1"},"Tissue RNA - adipose tissue [nTPM]":"34.4","Tissue RNA - adrenal gland [nTPM]":"75.1","Tissue RNA - amygdala [nTPM]":"23.3","Tissue RNA - appendix [nTPM]":"15.2","Tissue RNA - basal ganglia [nTPM]":"33.6","Tissue RNA - bone marrow [nTPM]":"37.9","Tissue RNA - breast [nTPM]":"27.5","Tissue RNA - cerebellum [nTPM]":"31.4","Tissue RNA - cerebral cortex [nTPM]":"29.3","Tissue RNA - cervix [nTPM]":"17.5","Tissue RNA - choroid plexus [nTPM]":"35.5","Tissue RNA - colon [nTPM]":"43.6","Tissue RNA - duodenum [nTPM]":"38.1","Tissue RNA - endometrium 1 [nTPM]":"13.8","Tissue RNA - epididymis [nTPM]":"13.9","Tissue RNA - esophagus [nTPM]":"26.3","Tissue RNA - fallopian tube [nTPM]":"19.2","Tissue RNA - gallbladder [nTPM]":"17.0","Tissue RNA - heart muscle [nTPM]":"94.6","Tissue RNA - hippocampal formation [nTPM]":"23.6","Tissue RNA - hypothalamus [nTPM]":"28.5","Tissue RNA - kidney [nTPM]":"88.9","Tissue RNA - liver [nTPM]":"202.1","Tissue RNA - lung [nTPM]":"14.8","Tissue RNA - lymph node [nTPM]":"16.2","Tissue RNA - medulla oblongata [nTPM]":"31.1","Tissue RNA - midbrain [nTPM]":"29.4","Tissue RNA - ovary [nTPM]":"12.1","Tissue RNA - pancreas [nTPM]":"32.0","Tissue RNA - parathyroid gland [nTPM]":"57.0","Tissue RNA - pituitary gland [nTPM]":"15.6","Tissue RNA - placenta [nTPM]":"19.6","Tissue RNA - pons [nTPM]":"30.4","Tissue RNA - prostate [nTPM]":"23.7","Tissue RNA - rectum [nTPM]":"41.9","Tissue RNA - retina [nTPM]":"17.2","Tissue RNA - salivary gland [nTPM]":"23.6","Tissue RNA - seminal vesicle [nTPM]":"21.7","Tissue RNA - skeletal muscle [nTPM]":"83.8","Tissue RNA - skin 1 [nTPM]":"15.1","Tissue RNA - small intestine [nTPM]":"27.5","Tissue RNA - smooth muscle [nTPM]":"22.6","Tissue RNA - spinal cord [nTPM]":"27.1","Tissue RNA - spleen [nTPM]":"12.7","Tissue RNA - stomach 1 [nTPM]":"26.1","Tissue RNA - testis [nTPM]":"38.8","Tissue RNA - thalamus [nTPM]":"29.8","Tissue RNA - thymus [nTPM]":"21.1","Tissue RNA - thyroid gland [nTPM]":"37.9","Tissue RNA - tongue [nTPM]":"91.4","Tissue RNA - tonsil [nTPM]":"20.7","Tissue RNA - urinary bladder [nTPM]":"20.5","Tissue RNA - vagina [nTPM]":"11.4","Tissue RNA - white matter [nTPM]":"47.8","Cell RNA - A-431 [nTPM]":"64.8","Cell RNA - A549 [nTPM]":"45.8","Cell RNA - AF22 [nTPM]":"42.4","Cell RNA - AN3-CA [nTPM]":"64.4","Cell RNA - ASC diff [nTPM]":"30.2","Cell RNA - ASC TERT1 [nTPM]":"34.5","Cell RNA - BEWO [nTPM]":"75.4","Cell RNA - BJ [nTPM]":"33.0","Cell RNA - BJ hTERT+ [nTPM]":"35.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"49.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"69.6","Cell RNA - CACO-2 [nTPM]":"67.9","Cell RNA - CAPAN-2 [nTPM]":"44.7","Cell RNA - Daudi [nTPM]":"80.3","Cell RNA - EFO-21 [nTPM]":"89.4","Cell RNA - fHDF\/TERT166 [nTPM]":"46.6","Cell RNA - GAMG [nTPM]":"44.0","Cell RNA - HaCaT [nTPM]":"35.1","Cell RNA - HAP1 [nTPM]":"50.3","Cell RNA - HBEC3-KT [nTPM]":"44.0","Cell RNA - HBF TERT88 [nTPM]":"69.4","Cell RNA - HDLM-2 [nTPM]":"47.8","Cell RNA - HEK 293 [nTPM]":"43.0","Cell RNA - HEL [nTPM]":"140.8","Cell RNA - HeLa [nTPM]":"49.5","Cell RNA - Hep G2 [nTPM]":"101.4","Cell RNA - HHSteC [nTPM]":"66.4","Cell RNA - HL-60 [nTPM]":"107.3","Cell RNA - HMC-1 [nTPM]":"60.2","Cell RNA - HSkMC [nTPM]":"40.8","Cell RNA - hTCEpi [nTPM]":"41.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"31.0","Cell RNA - hTERT-HME1 [nTPM]":"69.4","Cell RNA - hTERT-RPE1 [nTPM]":"30.5","Cell RNA - HUVEC TERT2 [nTPM]":"56.1","Cell RNA - JURKAT [nTPM]":"131.6","Cell RNA - K-562 [nTPM]":"104.5","Cell RNA - Karpas-707 [nTPM]":"41.0","Cell RNA - LHCN-M2 [nTPM]":"38.0","Cell RNA - MCF7 [nTPM]":"123.1","Cell RNA - MOLT-4 [nTPM]":"109.3","Cell RNA - NB-4 [nTPM]":"63.1","Cell RNA - NTERA-2 [nTPM]":"36.0","Cell RNA - OE19 [nTPM]":"96.8","Cell RNA - PC-3 [nTPM]":"40.9","Cell RNA - REH [nTPM]":"29.3","Cell RNA - RH-30 [nTPM]":"34.6","Cell RNA - RPMI-8226 [nTPM]":"116.6","Cell RNA - RPTEC TERT1 [nTPM]":"89.9","Cell RNA - RT4 [nTPM]":"69.4","Cell RNA - SCLC-21H [nTPM]":"84.0","Cell RNA - SH-SY5Y [nTPM]":"62.9","Cell RNA - SiHa [nTPM]":"84.4","Cell RNA - SK-BR-3 [nTPM]":"48.9","Cell RNA - SK-MEL-30 [nTPM]":"77.5","Cell RNA - SuSa [nTPM]":"35.2","Cell RNA - T-47d [nTPM]":"98.3","Cell RNA - THP-1 [nTPM]":"62.9","Cell RNA - TIME [nTPM]":"42.0","Cell RNA - U-138 MG [nTPM]":"24.5","Cell RNA - U-2 OS [nTPM]":"26.0","Cell RNA - U-2197 [nTPM]":"69.2","Cell RNA - U-251 MG [nTPM]":"29.6","Cell RNA - U-266\/70 [nTPM]":"78.3","Cell RNA - U-266\/84 [nTPM]":"70.0","Cell RNA - U-698 [nTPM]":"66.9","Cell RNA - U-87 MG [nTPM]":"34.9","Cell RNA - U-937 [nTPM]":"41.7","Cell RNA - WM-115 [nTPM]":"29.9","Blood RNA - basophil [nTPM]":"7.3","Blood RNA - classical monocyte [nTPM]":"29.5","Blood RNA - eosinophil [nTPM]":"7.5","Blood RNA - gdT-cell [nTPM]":"22.6","Blood RNA - intermediate monocyte [nTPM]":"30.8","Blood RNA - MAIT T-cell [nTPM]":"25.4","Blood RNA - memory B-cell [nTPM]":"21.7","Blood RNA - memory CD4 T-cell [nTPM]":"14.7","Blood RNA - memory CD8 T-cell [nTPM]":"23.2","Blood RNA - myeloid DC [nTPM]":"44.6","Blood RNA - naive B-cell [nTPM]":"19.8","Blood RNA - naive CD4 T-cell [nTPM]":"15.1","Blood RNA - naive CD8 T-cell [nTPM]":"18.7","Blood RNA - neutrophil [nTPM]":"2.7","Blood RNA - NK-cell [nTPM]":"25.9","Blood RNA - non-classical monocyte [nTPM]":"28.7","Blood RNA - plasmacytoid DC [nTPM]":"38.5","Blood RNA - T-reg [nTPM]":"14.8","Blood RNA - total PBMC [nTPM]":"22.6","Brain RNA - amygdala [nTPM]":"23.3","Brain RNA - basal ganglia [nTPM]":"33.6","Brain RNA - cerebellum [nTPM]":"31.4","Brain RNA - cerebral cortex [nTPM]":"29.3","Brain RNA - hippocampal formation [nTPM]":"23.6","Brain RNA - hypothalamus [nTPM]":"28.5","Brain RNA - medulla oblongata [nTPM]":"31.1","Brain RNA - midbrain [nTPM]":"29.4","Brain RNA - pons [nTPM]":"30.4","Brain RNA - spinal cord [nTPM]":"27.1","Brain RNA - thalamus [nTPM]":"29.8","Brain RNA - white matter [nTPM]":"47.8","Single Cell Type RNA - Adipocytes [nTPM]":"5.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.0","Single Cell Type RNA - Astrocytes [nTPM]":"16.0","Single Cell Type RNA - B-cells [nTPM]":"9.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"37.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"16.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"51.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"28.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"57.1","Single Cell Type RNA - dendritic cells [nTPM]":"8.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"39.2","Single Cell Type RNA - Ductal cells [nTPM]":"24.6","Single Cell Type RNA - Early spermatids [nTPM]":"316.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.5","Single Cell Type RNA - Endothelial cells [nTPM]":"8.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.1","Single Cell Type RNA - Erythroid cells [nTPM]":"53.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"27.1","Single Cell Type RNA - Fibroblasts [nTPM]":"13.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.1","Single Cell Type RNA - granulocytes [nTPM]":"29.2","Single Cell Type RNA - Granulosa cells [nTPM]":"18.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.3","Single Cell Type RNA - Hepatocytes [nTPM]":"76.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"35.1","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.1","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"11.7","Single Cell Type RNA - Langerhans cells [nTPM]":"5.2","Single Cell Type RNA - Late spermatids [nTPM]":"159.0","Single Cell Type RNA - Leydig cells [nTPM]":"13.7","Single Cell Type RNA - Macrophages [nTPM]":"11.4","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"16.5","Single Cell Type RNA - Muller glia cells [nTPM]":"11.8","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"22.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"50.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.4","Single Cell Type RNA - Paneth cells [nTPM]":"16.7","Single Cell Type RNA - Peritubular cells [nTPM]":"10.9","Single Cell Type RNA - Plasma cells [nTPM]":"22.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"19.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"97.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.1","Single Cell Type RNA - Spermatocytes [nTPM]":"11.3","Single Cell Type RNA - Spermatogonia [nTPM]":"29.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"50.9","Single Cell Type RNA - T-cells [nTPM]":"9.9","Single Cell Type RNA - Theca cells [nTPM]":"52.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"25.1","Single Cell Type RNA - Urothelial cells [nTPM]":"12.2"},{"Gene":"PCK1","Gene synonym":["PEPCK-C"],"Ensembl":"ENSG00000124253","Gene description":"Phosphoenolpyruvate carboxykinase 1","Uniprot":["P35558"],"Chromosome":"20","Position":"57561080-57568121","Protein class":["Citric acid cycle related proteins","Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Gluconeogenesis"],"Molecular function":["Decarboxylase","Kinase","Lyase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"432.1","liver":"681.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"703.8","Distal tubular cells":"588.9","Hepatocytes":"1184.0","Proximal enterocytes":"2209.9","Proximal tubular cells":"3547.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"liver cancer":"99.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"ASC diff":"20.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006277","HPA006507","CAB017027"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"840000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB017027":null,"HPA006277":"AB_1079579","HPA006507":"AB_1079578"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.47e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Tissue RNA - adipose tissue [nTPM]":"59.2","Tissue RNA - adrenal gland [nTPM]":"1.1","Tissue RNA - amygdala [nTPM]":"0.8","Tissue RNA - appendix [nTPM]":"1.7","Tissue RNA - basal ganglia [nTPM]":"0.8","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"29.8","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"1.6","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"57.8","Tissue RNA - duodenum [nTPM]":"110.4","Tissue RNA - endometrium 1 [nTPM]":"1.2","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"5.0","Tissue RNA - heart muscle [nTPM]":"1.0","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"1.4","Tissue RNA - kidney [nTPM]":"432.1","Tissue RNA - liver [nTPM]":"681.4","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"0.7","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"1.6","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"21.1","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"0.8","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"79.8","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"1.1","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"143.9","Tissue RNA - smooth muscle [nTPM]":"2.9","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"0.9","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"1.3","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.8","Tissue RNA - tongue [nTPM]":"6.5","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.8","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"20.5","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.7","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"2.2","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.8","Brain RNA - basal ganglia [nTPM]":"0.8","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"1.6","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"1.4","Brain RNA - medulla oblongata [nTPM]":"0.7","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"0.8","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"1.3","Brain RNA - white matter [nTPM]":"0.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"21.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"61.5","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"90.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"703.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"588.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.5","Single Cell Type RNA - Endothelial cells [nTPM]":"2.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"53.9","Single Cell Type RNA - Erythroid cells [nTPM]":"40.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.5","Single Cell Type RNA - granulocytes [nTPM]":"8.9","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"29.6","Single Cell Type RNA - Hepatocytes [nTPM]":"1184.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"293.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"22.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"12.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"9.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"285.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2209.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3547.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"10.2","Single Cell Type RNA - Theca cells [nTPM]":"1.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"348.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"PCK2","Gene synonym":["PEPCK","PEPCK2"],"Ensembl":"ENSG00000100889","Gene description":"Phosphoenolpyruvate carboxykinase 2, mitochondrial","Uniprot":["Q16822"],"Chromosome":"14","Position":"24094053-24110598","Protein class":["Citric acid cycle related proteins","Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Gluconeogenesis"],"Molecular function":["Decarboxylase","Lyase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"intestine":"196.1","kidney":"99.1","liver":"374.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hepatocytes":"309.3","Proximal enterocytes":"752.6","Proximal tubular cells":"237.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"91.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HHSteC":"104.7","hTCEpi":"104.7","SK-MEL-30":"103.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB018734","HPA051162","HPA053502"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3500000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB018734":"AB_2160168","HPA051162":"AB_2681368","HPA053502":"AB_2682171"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.81e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Tissue RNA - adipose tissue [nTPM]":"25.5","Tissue RNA - adrenal gland [nTPM]":"10.7","Tissue RNA - amygdala [nTPM]":"3.2","Tissue RNA - appendix [nTPM]":"8.0","Tissue RNA - basal ganglia [nTPM]":"3.9","Tissue RNA - bone marrow [nTPM]":"4.5","Tissue RNA - breast [nTPM]":"21.1","Tissue RNA - cerebellum [nTPM]":"3.8","Tissue RNA - cerebral cortex [nTPM]":"3.3","Tissue RNA - cervix [nTPM]":"6.8","Tissue RNA - choroid plexus [nTPM]":"3.4","Tissue RNA - colon [nTPM]":"44.8","Tissue RNA - duodenum [nTPM]":"196.1","Tissue RNA - endometrium 1 [nTPM]":"5.8","Tissue RNA - epididymis [nTPM]":"3.1","Tissue RNA - esophagus [nTPM]":"20.0","Tissue RNA - fallopian tube [nTPM]":"5.9","Tissue RNA - gallbladder [nTPM]":"4.5","Tissue RNA - heart muscle [nTPM]":"5.8","Tissue RNA - hippocampal formation [nTPM]":"3.1","Tissue RNA - hypothalamus [nTPM]":"3.9","Tissue RNA - kidney [nTPM]":"99.1","Tissue RNA - liver [nTPM]":"374.1","Tissue RNA - lung [nTPM]":"16.5","Tissue RNA - lymph node [nTPM]":"8.7","Tissue RNA - medulla oblongata [nTPM]":"4.6","Tissue RNA - midbrain [nTPM]":"4.2","Tissue RNA - ovary [nTPM]":"3.0","Tissue RNA - pancreas [nTPM]":"34.8","Tissue RNA - parathyroid gland [nTPM]":"17.4","Tissue RNA - pituitary gland [nTPM]":"8.0","Tissue RNA - placenta [nTPM]":"2.8","Tissue RNA - pons [nTPM]":"4.1","Tissue RNA - prostate [nTPM]":"9.1","Tissue RNA - rectum [nTPM]":"19.2","Tissue RNA - retina [nTPM]":"2.7","Tissue RNA - salivary gland [nTPM]":"18.6","Tissue RNA - seminal vesicle [nTPM]":"7.1","Tissue RNA - skeletal muscle [nTPM]":"2.6","Tissue RNA - skin 1 [nTPM]":"12.6","Tissue RNA - small intestine [nTPM]":"136.3","Tissue RNA - smooth muscle [nTPM]":"3.8","Tissue RNA - spinal cord [nTPM]":"4.0","Tissue RNA - spleen [nTPM]":"21.7","Tissue RNA - stomach 1 [nTPM]":"16.0","Tissue RNA - testis [nTPM]":"19.7","Tissue RNA - thalamus [nTPM]":"3.9","Tissue RNA - thymus [nTPM]":"3.7","Tissue RNA - thyroid gland [nTPM]":"18.9","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"7.5","Tissue RNA - urinary bladder [nTPM]":"10.8","Tissue RNA - vagina [nTPM]":"10.0","Tissue RNA - white matter [nTPM]":"4.3","Cell RNA - A-431 [nTPM]":"17.6","Cell RNA - A549 [nTPM]":"9.8","Cell RNA - AF22 [nTPM]":"2.7","Cell RNA - AN3-CA [nTPM]":"18.1","Cell RNA - ASC diff [nTPM]":"11.0","Cell RNA - ASC TERT1 [nTPM]":"10.5","Cell RNA - BEWO [nTPM]":"46.0","Cell RNA - BJ [nTPM]":"21.5","Cell RNA - BJ hTERT+ [nTPM]":"25.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"28.4","Cell RNA - CACO-2 [nTPM]":"16.1","Cell RNA - CAPAN-2 [nTPM]":"19.9","Cell RNA - Daudi [nTPM]":"44.6","Cell RNA - EFO-21 [nTPM]":"2.6","Cell RNA - fHDF\/TERT166 [nTPM]":"33.4","Cell RNA - GAMG [nTPM]":"5.6","Cell RNA - HaCaT [nTPM]":"25.4","Cell RNA - HAP1 [nTPM]":"18.0","Cell RNA - HBEC3-KT [nTPM]":"28.1","Cell RNA - HBF TERT88 [nTPM]":"13.8","Cell RNA - HDLM-2 [nTPM]":"22.8","Cell RNA - HEK 293 [nTPM]":"0.8","Cell RNA - HEL [nTPM]":"8.0","Cell RNA - HeLa [nTPM]":"5.0","Cell RNA - Hep G2 [nTPM]":"84.2","Cell RNA - HHSteC [nTPM]":"104.7","Cell RNA - HL-60 [nTPM]":"15.8","Cell RNA - HMC-1 [nTPM]":"33.4","Cell RNA - HSkMC [nTPM]":"12.9","Cell RNA - hTCEpi [nTPM]":"104.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.6","Cell RNA - hTERT-HME1 [nTPM]":"26.5","Cell RNA - hTERT-RPE1 [nTPM]":"5.0","Cell RNA - HUVEC TERT2 [nTPM]":"14.0","Cell RNA - JURKAT [nTPM]":"50.6","Cell RNA - K-562 [nTPM]":"23.4","Cell RNA - Karpas-707 [nTPM]":"79.3","Cell RNA - LHCN-M2 [nTPM]":"6.4","Cell RNA - MCF7 [nTPM]":"74.6","Cell RNA - MOLT-4 [nTPM]":"4.0","Cell RNA - NB-4 [nTPM]":"7.6","Cell RNA - NTERA-2 [nTPM]":"3.1","Cell RNA - OE19 [nTPM]":"39.4","Cell RNA - PC-3 [nTPM]":"13.0","Cell RNA - REH [nTPM]":"8.7","Cell RNA - RH-30 [nTPM]":"10.5","Cell RNA - RPMI-8226 [nTPM]":"26.0","Cell RNA - RPTEC TERT1 [nTPM]":"5.3","Cell RNA - RT4 [nTPM]":"26.7","Cell RNA - SCLC-21H [nTPM]":"11.3","Cell RNA - SH-SY5Y [nTPM]":"18.2","Cell RNA - SiHa [nTPM]":"16.5","Cell RNA - SK-BR-3 [nTPM]":"21.2","Cell RNA - SK-MEL-30 [nTPM]":"103.9","Cell RNA - SuSa [nTPM]":"2.6","Cell RNA - T-47d [nTPM]":"28.5","Cell RNA - THP-1 [nTPM]":"24.1","Cell RNA - TIME [nTPM]":"2.7","Cell RNA - U-138 MG [nTPM]":"3.8","Cell RNA - U-2 OS [nTPM]":"19.7","Cell RNA - U-2197 [nTPM]":"5.6","Cell RNA - U-251 MG [nTPM]":"6.0","Cell RNA - U-266\/70 [nTPM]":"53.2","Cell RNA - U-266\/84 [nTPM]":"18.6","Cell RNA - U-698 [nTPM]":"11.0","Cell RNA - U-87 MG [nTPM]":"10.6","Cell RNA - U-937 [nTPM]":"24.5","Cell RNA - WM-115 [nTPM]":"9.6","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"11.6","Blood RNA - eosinophil [nTPM]":"3.5","Blood RNA - gdT-cell [nTPM]":"4.0","Blood RNA - intermediate monocyte [nTPM]":"21.6","Blood RNA - MAIT T-cell [nTPM]":"4.1","Blood RNA - memory B-cell [nTPM]":"11.4","Blood RNA - memory CD4 T-cell [nTPM]":"4.5","Blood RNA - memory CD8 T-cell [nTPM]":"4.5","Blood RNA - myeloid DC [nTPM]":"15.3","Blood RNA - naive B-cell [nTPM]":"7.3","Blood RNA - naive CD4 T-cell [nTPM]":"2.7","Blood RNA - naive CD8 T-cell [nTPM]":"2.5","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"2.2","Blood RNA - non-classical monocyte [nTPM]":"22.0","Blood RNA - plasmacytoid DC [nTPM]":"2.5","Blood RNA - T-reg [nTPM]":"9.1","Blood RNA - total PBMC [nTPM]":"6.1","Brain RNA - amygdala [nTPM]":"3.2","Brain RNA - basal ganglia [nTPM]":"3.9","Brain RNA - cerebellum [nTPM]":"3.8","Brain RNA - cerebral cortex [nTPM]":"3.3","Brain RNA - hippocampal formation [nTPM]":"3.1","Brain RNA - hypothalamus [nTPM]":"3.9","Brain RNA - medulla oblongata [nTPM]":"4.6","Brain RNA - midbrain [nTPM]":"4.2","Brain RNA - pons [nTPM]":"4.1","Brain RNA - spinal cord [nTPM]":"4.0","Brain RNA - thalamus [nTPM]":"3.9","Brain RNA - white matter [nTPM]":"4.3","Single Cell Type RNA - Adipocytes [nTPM]":"4.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"28.5","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"17.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"4.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"8.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.7","Single Cell Type RNA - dendritic cells [nTPM]":"4.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"91.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"18.9","Single Cell Type RNA - Early spermatids [nTPM]":"60.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.2","Single Cell Type RNA - Endothelial cells [nTPM]":"5.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.1","Single Cell Type RNA - Erythroid cells [nTPM]":"24.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"76.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.3","Single Cell Type RNA - Fibroblasts [nTPM]":"7.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"1.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.2","Single Cell Type RNA - Hepatocytes [nTPM]":"309.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"63.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"60.8","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"25.8","Single Cell Type RNA - Langerhans cells [nTPM]":"5.7","Single Cell Type RNA - Late spermatids [nTPM]":"30.8","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"16.4","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"22.9","Single Cell Type RNA - Muller glia cells [nTPM]":"5.8","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.0","Single Cell Type RNA - Paneth cells [nTPM]":"87.8","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"13.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"752.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"237.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.7","Single Cell Type RNA - Spermatocytes [nTPM]":"19.8","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.0","Single Cell Type RNA - T-cells [nTPM]":"7.6","Single Cell Type RNA - Theca cells [nTPM]":"6.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"72.0","Single Cell Type RNA - Urothelial cells [nTPM]":"15.0"},{"Gene":"PCSK1","Gene synonym":["NEC1","PC1","PC3","SPC3"],"Ensembl":"ENSG00000175426","Gene description":"Proprotein convertase subtilisin\/kexin type 1","Uniprot":["P29120"],"Chromosome":"5","Position":"96390333-96434143","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Disease variant","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"68.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Enteroendocrine cells":"224.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"12.1"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebral cortex":"19.1","hypothalamus":"68.3","pons":"30.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"SCLC-21H":"22.6","U-138 MG":"19.0","U-87 MG":"15.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048564","HPA079656"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 17: Intestinal endocrine cells - Hormone signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA048564":"AB_2680444","HPA079656":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.13e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.47e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.84e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.37e-3"},"Tissue RNA - adipose tissue [nTPM]":"1.7","Tissue RNA - adrenal gland [nTPM]":"6.3","Tissue RNA - amygdala [nTPM]":"5.5","Tissue RNA - appendix [nTPM]":"4.7","Tissue RNA - basal ganglia [nTPM]":"3.7","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"1.4","Tissue RNA - cerebellum [nTPM]":"1.0","Tissue RNA - cerebral cortex [nTPM]":"19.1","Tissue RNA - cervix [nTPM]":"0.9","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"2.4","Tissue RNA - duodenum [nTPM]":"5.2","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"0.8","Tissue RNA - hippocampal formation [nTPM]":"3.0","Tissue RNA - hypothalamus [nTPM]":"68.3","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"6.6","Tissue RNA - midbrain [nTPM]":"7.7","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"7.6","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"12.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"30.0","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"2.3","Tissue RNA - retina [nTPM]":"8.7","Tissue RNA - salivary gland [nTPM]":"2.7","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"1.1","Tissue RNA - small intestine [nTPM]":"3.6","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"4.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"5.7","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"6.6","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"1.9","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"2.0","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"5.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"2.3","Cell RNA - ASC TERT1 [nTPM]":"0.7","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"1.0","Cell RNA - GAMG [nTPM]":"3.8","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.8","Cell RNA - HeLa [nTPM]":"2.4","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"2.0","Cell RNA - hTCEpi [nTPM]":"1.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.4","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.9","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"22.6","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"3.3","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"1.2","Cell RNA - U-138 MG [nTPM]":"19.0","Cell RNA - U-2 OS [nTPM]":"0.6","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"15.8","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"5.5","Brain RNA - basal ganglia [nTPM]":"3.7","Brain RNA - cerebellum [nTPM]":"1.0","Brain RNA - cerebral cortex [nTPM]":"19.1","Brain RNA - hippocampal formation [nTPM]":"3.0","Brain RNA - hypothalamus [nTPM]":"68.3","Brain RNA - medulla oblongata [nTPM]":"6.6","Brain RNA - midbrain [nTPM]":"7.7","Brain RNA - pons [nTPM]":"30.0","Brain RNA - spinal cord [nTPM]":"4.0","Brain RNA - thalamus [nTPM]":"6.6","Brain RNA - white matter [nTPM]":"5.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"3.6","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"13.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"224.6","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"54.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.7","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.7","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PCYT1A","Gene synonym":["CT","CTPCT","PCYT1"],"Ensembl":"ENSG00000161217","Gene description":"Phosphate cytidylyltransferase 1, choline, alpha","Uniprot":["P49585"],"Chromosome":"3","Position":"196214222-196287957","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Nucleotidyltransferase","Transferase"],"Disease involvement":["Cone-rod dystrophy","Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"215.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035428"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA035428":"AB_10602045"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.61e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.65e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.52e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Tissue RNA - adipose tissue [nTPM]":"31.4","Tissue RNA - adrenal gland [nTPM]":"24.4","Tissue RNA - amygdala [nTPM]":"15.2","Tissue RNA - appendix [nTPM]":"30.0","Tissue RNA - basal ganglia [nTPM]":"16.0","Tissue RNA - bone marrow [nTPM]":"45.3","Tissue RNA - breast [nTPM]":"21.0","Tissue RNA - cerebellum [nTPM]":"16.6","Tissue RNA - cerebral cortex [nTPM]":"15.8","Tissue RNA - cervix [nTPM]":"16.7","Tissue RNA - choroid plexus [nTPM]":"17.8","Tissue RNA - colon [nTPM]":"25.7","Tissue RNA - duodenum [nTPM]":"60.3","Tissue RNA - endometrium 1 [nTPM]":"19.1","Tissue RNA - epididymis [nTPM]":"13.9","Tissue RNA - esophagus [nTPM]":"31.0","Tissue RNA - fallopian tube [nTPM]":"15.6","Tissue RNA - gallbladder [nTPM]":"20.7","Tissue RNA - heart muscle [nTPM]":"46.4","Tissue RNA - hippocampal formation [nTPM]":"15.5","Tissue RNA - hypothalamus [nTPM]":"21.1","Tissue RNA - kidney [nTPM]":"18.3","Tissue RNA - liver [nTPM]":"20.7","Tissue RNA - lung [nTPM]":"22.5","Tissue RNA - lymph node [nTPM]":"22.9","Tissue RNA - medulla oblongata [nTPM]":"18.8","Tissue RNA - midbrain [nTPM]":"18.0","Tissue RNA - ovary [nTPM]":"15.8","Tissue RNA - pancreas [nTPM]":"16.8","Tissue RNA - parathyroid gland [nTPM]":"22.7","Tissue RNA - pituitary gland [nTPM]":"12.9","Tissue RNA - placenta [nTPM]":"20.1","Tissue RNA - pons [nTPM]":"18.5","Tissue RNA - prostate [nTPM]":"16.6","Tissue RNA - rectum [nTPM]":"22.9","Tissue RNA - retina [nTPM]":"14.4","Tissue RNA - salivary gland [nTPM]":"19.3","Tissue RNA - seminal vesicle [nTPM]":"18.6","Tissue RNA - skeletal muscle [nTPM]":"73.8","Tissue RNA - skin 1 [nTPM]":"43.0","Tissue RNA - small intestine [nTPM]":"49.1","Tissue RNA - smooth muscle [nTPM]":"23.0","Tissue RNA - spinal cord [nTPM]":"17.5","Tissue RNA - spleen [nTPM]":"25.9","Tissue RNA - stomach 1 [nTPM]":"24.2","Tissue RNA - testis [nTPM]":"22.4","Tissue RNA - thalamus [nTPM]":"18.1","Tissue RNA - thymus [nTPM]":"18.1","Tissue RNA - thyroid gland [nTPM]":"17.2","Tissue RNA - tongue [nTPM]":"42.1","Tissue RNA - tonsil [nTPM]":"26.8","Tissue RNA - urinary bladder [nTPM]":"21.0","Tissue RNA - vagina [nTPM]":"19.8","Tissue RNA - white matter [nTPM]":"17.1","Cell RNA - A-431 [nTPM]":"92.6","Cell RNA - A549 [nTPM]":"36.6","Cell RNA - AF22 [nTPM]":"25.8","Cell RNA - AN3-CA [nTPM]":"37.2","Cell RNA - ASC diff [nTPM]":"52.2","Cell RNA - ASC TERT1 [nTPM]":"53.9","Cell RNA - BEWO [nTPM]":"37.0","Cell RNA - BJ [nTPM]":"68.2","Cell RNA - BJ hTERT+ [nTPM]":"47.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"59.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"51.8","Cell RNA - CACO-2 [nTPM]":"92.3","Cell RNA - CAPAN-2 [nTPM]":"32.8","Cell RNA - Daudi [nTPM]":"23.9","Cell RNA - EFO-21 [nTPM]":"215.2","Cell RNA - fHDF\/TERT166 [nTPM]":"78.1","Cell RNA - GAMG [nTPM]":"60.2","Cell RNA - HaCaT [nTPM]":"71.4","Cell RNA - HAP1 [nTPM]":"40.5","Cell RNA - HBEC3-KT [nTPM]":"52.1","Cell RNA - HBF TERT88 [nTPM]":"50.4","Cell RNA - HDLM-2 [nTPM]":"42.1","Cell RNA - HEK 293 [nTPM]":"28.6","Cell RNA - HEL [nTPM]":"68.6","Cell RNA - HeLa [nTPM]":"40.6","Cell RNA - Hep G2 [nTPM]":"39.5","Cell RNA - HHSteC [nTPM]":"45.2","Cell RNA - HL-60 [nTPM]":"34.3","Cell RNA - HMC-1 [nTPM]":"56.7","Cell RNA - HSkMC [nTPM]":"47.4","Cell RNA - hTCEpi [nTPM]":"40.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"55.9","Cell RNA - hTERT-HME1 [nTPM]":"39.6","Cell RNA - hTERT-RPE1 [nTPM]":"35.4","Cell RNA - HUVEC TERT2 [nTPM]":"63.0","Cell RNA - JURKAT [nTPM]":"21.0","Cell RNA - K-562 [nTPM]":"38.3","Cell RNA - Karpas-707 [nTPM]":"53.3","Cell RNA - LHCN-M2 [nTPM]":"58.1","Cell RNA - MCF7 [nTPM]":"79.6","Cell RNA - MOLT-4 [nTPM]":"19.9","Cell RNA - NB-4 [nTPM]":"17.3","Cell RNA - NTERA-2 [nTPM]":"21.4","Cell RNA - OE19 [nTPM]":"55.7","Cell RNA - PC-3 [nTPM]":"53.0","Cell RNA - REH [nTPM]":"34.5","Cell RNA - RH-30 [nTPM]":"31.0","Cell RNA - RPMI-8226 [nTPM]":"37.5","Cell RNA - RPTEC TERT1 [nTPM]":"35.7","Cell RNA - RT4 [nTPM]":"53.6","Cell RNA - SCLC-21H [nTPM]":"25.4","Cell RNA - SH-SY5Y [nTPM]":"18.3","Cell RNA - SiHa [nTPM]":"44.5","Cell RNA - SK-BR-3 [nTPM]":"79.5","Cell RNA - SK-MEL-30 [nTPM]":"44.2","Cell RNA - SuSa [nTPM]":"32.8","Cell RNA - T-47d [nTPM]":"114.1","Cell RNA - THP-1 [nTPM]":"37.2","Cell RNA - TIME [nTPM]":"88.5","Cell RNA - U-138 MG [nTPM]":"45.5","Cell RNA - U-2 OS [nTPM]":"25.2","Cell RNA - U-2197 [nTPM]":"61.8","Cell RNA - U-251 MG [nTPM]":"92.7","Cell RNA - U-266\/70 [nTPM]":"45.8","Cell RNA - U-266\/84 [nTPM]":"101.1","Cell RNA - U-698 [nTPM]":"44.1","Cell RNA - U-87 MG [nTPM]":"69.6","Cell RNA - U-937 [nTPM]":"43.8","Cell RNA - WM-115 [nTPM]":"56.9","Blood RNA - basophil [nTPM]":"9.6","Blood RNA - classical monocyte [nTPM]":"9.2","Blood RNA - eosinophil [nTPM]":"10.4","Blood RNA - gdT-cell [nTPM]":"8.8","Blood RNA - intermediate monocyte [nTPM]":"9.3","Blood RNA - MAIT T-cell [nTPM]":"7.5","Blood RNA - memory B-cell [nTPM]":"7.2","Blood RNA - memory CD4 T-cell [nTPM]":"6.5","Blood RNA - memory CD8 T-cell [nTPM]":"9.7","Blood RNA - myeloid DC [nTPM]":"9.1","Blood RNA - naive B-cell [nTPM]":"6.3","Blood RNA - naive CD4 T-cell [nTPM]":"4.2","Blood RNA - naive CD8 T-cell [nTPM]":"6.3","Blood RNA - neutrophil [nTPM]":"21.0","Blood RNA - NK-cell [nTPM]":"9.4","Blood RNA - non-classical monocyte [nTPM]":"11.0","Blood RNA - plasmacytoid DC [nTPM]":"5.9","Blood RNA - T-reg [nTPM]":"14.9","Blood RNA - total PBMC [nTPM]":"5.2","Brain RNA - amygdala [nTPM]":"15.2","Brain RNA - basal ganglia [nTPM]":"16.0","Brain RNA - cerebellum [nTPM]":"16.6","Brain RNA - cerebral cortex [nTPM]":"15.8","Brain RNA - hippocampal formation [nTPM]":"15.5","Brain RNA - hypothalamus [nTPM]":"21.1","Brain RNA - medulla oblongata [nTPM]":"18.8","Brain RNA - midbrain [nTPM]":"18.0","Brain RNA - pons [nTPM]":"18.5","Brain RNA - spinal cord [nTPM]":"17.5","Brain RNA - thalamus [nTPM]":"18.1","Brain RNA - white matter [nTPM]":"17.1","Single Cell Type RNA - Adipocytes [nTPM]":"24.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.7","Single Cell Type RNA - Astrocytes [nTPM]":"15.3","Single Cell Type RNA - B-cells [nTPM]":"19.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"19.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"15.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"70.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"17.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.9","Single Cell Type RNA - dendritic cells [nTPM]":"27.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"36.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"24.8","Single Cell Type RNA - Early spermatids [nTPM]":"76.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.9","Single Cell Type RNA - Endothelial cells [nTPM]":"23.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.1","Single Cell Type RNA - Erythroid cells [nTPM]":"12.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"20.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"22.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.7","Single Cell Type RNA - Fibroblasts [nTPM]":"17.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.6","Single Cell Type RNA - granulocytes [nTPM]":"20.8","Single Cell Type RNA - Granulosa cells [nTPM]":"16.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.7","Single Cell Type RNA - Hepatocytes [nTPM]":"35.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"37.4","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.2","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"34.6","Single Cell Type RNA - Langerhans cells [nTPM]":"27.1","Single Cell Type RNA - Late spermatids [nTPM]":"67.6","Single Cell Type RNA - Leydig cells [nTPM]":"19.9","Single Cell Type RNA - Macrophages [nTPM]":"33.9","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"39.4","Single Cell Type RNA - Muller glia cells [nTPM]":"13.1","Single Cell Type RNA - NK-cells [nTPM]":"39.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"24.6","Single Cell Type RNA - Paneth cells [nTPM]":"21.1","Single Cell Type RNA - Peritubular cells [nTPM]":"28.2","Single Cell Type RNA - Plasma cells [nTPM]":"27.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"67.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.8","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.0","Single Cell Type RNA - Spermatocytes [nTPM]":"46.0","Single Cell Type RNA - Spermatogonia [nTPM]":"13.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"30.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"18.6","Single Cell Type RNA - T-cells [nTPM]":"25.6","Single Cell Type RNA - Theca cells [nTPM]":"25.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.8","Single Cell Type RNA - Urothelial cells [nTPM]":"12.2"},{"Gene":"PCYT2","Gene synonym":["ET"],"Ensembl":"ENSG00000185813","Gene description":"Phosphate cytidylyltransferase 2, ethanolamine","Uniprot":["Q99447"],"Chromosome":"17","Position":"81900958-81911432","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Nucleotidyltransferase","Transferase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"165.7","testis":"261.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Early spermatids":"763.2","Late spermatids":"2829.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"218.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023033","HPA023034"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"84000","Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA023033":"AB_1855094","HPA023034":"AB_1855095"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.97e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.29e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-2"},"Tissue RNA - adipose tissue [nTPM]":"29.7","Tissue RNA - adrenal gland [nTPM]":"16.8","Tissue RNA - amygdala [nTPM]":"40.0","Tissue RNA - appendix [nTPM]":"9.5","Tissue RNA - basal ganglia [nTPM]":"40.1","Tissue RNA - bone marrow [nTPM]":"12.1","Tissue RNA - breast [nTPM]":"25.2","Tissue RNA - cerebellum [nTPM]":"44.4","Tissue RNA - cerebral cortex [nTPM]":"45.8","Tissue RNA - cervix [nTPM]":"14.9","Tissue RNA - choroid plexus [nTPM]":"30.4","Tissue RNA - colon [nTPM]":"25.5","Tissue RNA - duodenum [nTPM]":"63.9","Tissue RNA - endometrium 1 [nTPM]":"18.0","Tissue RNA - epididymis [nTPM]":"13.5","Tissue RNA - esophagus [nTPM]":"26.3","Tissue RNA - fallopian tube [nTPM]":"23.9","Tissue RNA - gallbladder [nTPM]":"9.9","Tissue RNA - heart muscle [nTPM]":"47.7","Tissue RNA - hippocampal formation [nTPM]":"41.2","Tissue RNA - hypothalamus [nTPM]":"37.7","Tissue RNA - kidney [nTPM]":"44.0","Tissue RNA - liver [nTPM]":"165.7","Tissue RNA - lung [nTPM]":"21.3","Tissue RNA - lymph node [nTPM]":"12.0","Tissue RNA - medulla oblongata [nTPM]":"47.0","Tissue RNA - midbrain [nTPM]":"43.0","Tissue RNA - ovary [nTPM]":"20.9","Tissue RNA - pancreas [nTPM]":"25.3","Tissue RNA - parathyroid gland [nTPM]":"20.2","Tissue RNA - pituitary gland [nTPM]":"14.4","Tissue RNA - placenta [nTPM]":"12.0","Tissue RNA - pons [nTPM]":"47.3","Tissue RNA - prostate [nTPM]":"24.2","Tissue RNA - rectum [nTPM]":"16.7","Tissue RNA - retina [nTPM]":"8.6","Tissue RNA - salivary gland [nTPM]":"22.3","Tissue RNA - seminal vesicle [nTPM]":"12.1","Tissue RNA - skeletal muscle [nTPM]":"33.5","Tissue RNA - skin 1 [nTPM]":"16.3","Tissue RNA - small intestine [nTPM]":"43.0","Tissue RNA - smooth muscle [nTPM]":"9.6","Tissue RNA - spinal cord [nTPM]":"41.3","Tissue RNA - spleen [nTPM]":"12.8","Tissue RNA - stomach 1 [nTPM]":"35.4","Tissue RNA - testis [nTPM]":"261.7","Tissue RNA - thalamus [nTPM]":"41.0","Tissue RNA - thymus [nTPM]":"13.5","Tissue RNA - thyroid gland [nTPM]":"16.2","Tissue RNA - tongue [nTPM]":"29.3","Tissue RNA - tonsil [nTPM]":"11.9","Tissue RNA - urinary bladder [nTPM]":"21.2","Tissue RNA - vagina [nTPM]":"15.1","Tissue RNA - white matter [nTPM]":"44.0","Cell RNA - A-431 [nTPM]":"42.6","Cell RNA - A549 [nTPM]":"23.9","Cell RNA - AF22 [nTPM]":"18.8","Cell RNA - AN3-CA [nTPM]":"53.1","Cell RNA - ASC diff [nTPM]":"91.8","Cell RNA - ASC TERT1 [nTPM]":"48.0","Cell RNA - BEWO [nTPM]":"27.9","Cell RNA - BJ [nTPM]":"29.9","Cell RNA - BJ hTERT+ [nTPM]":"63.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"40.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"48.0","Cell RNA - CACO-2 [nTPM]":"94.0","Cell RNA - CAPAN-2 [nTPM]":"43.0","Cell RNA - Daudi [nTPM]":"14.8","Cell RNA - EFO-21 [nTPM]":"16.0","Cell RNA - fHDF\/TERT166 [nTPM]":"31.1","Cell RNA - GAMG [nTPM]":"75.3","Cell RNA - HaCaT [nTPM]":"34.5","Cell RNA - HAP1 [nTPM]":"28.6","Cell RNA - HBEC3-KT [nTPM]":"55.1","Cell RNA - HBF TERT88 [nTPM]":"23.5","Cell RNA - HDLM-2 [nTPM]":"4.5","Cell RNA - HEK 293 [nTPM]":"24.3","Cell RNA - HEL [nTPM]":"32.1","Cell RNA - HeLa [nTPM]":"33.3","Cell RNA - Hep G2 [nTPM]":"218.2","Cell RNA - HHSteC [nTPM]":"97.8","Cell RNA - HL-60 [nTPM]":"32.5","Cell RNA - HMC-1 [nTPM]":"26.0","Cell RNA - HSkMC [nTPM]":"39.8","Cell RNA - hTCEpi [nTPM]":"31.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"36.8","Cell RNA - hTERT-HME1 [nTPM]":"28.4","Cell RNA - hTERT-RPE1 [nTPM]":"14.5","Cell RNA - HUVEC TERT2 [nTPM]":"38.6","Cell RNA - JURKAT [nTPM]":"44.0","Cell RNA - K-562 [nTPM]":"60.6","Cell RNA - Karpas-707 [nTPM]":"29.6","Cell RNA - LHCN-M2 [nTPM]":"30.8","Cell RNA - MCF7 [nTPM]":"35.7","Cell RNA - MOLT-4 [nTPM]":"39.3","Cell RNA - NB-4 [nTPM]":"40.1","Cell RNA - NTERA-2 [nTPM]":"15.1","Cell RNA - OE19 [nTPM]":"147.2","Cell RNA - PC-3 [nTPM]":"25.9","Cell RNA - REH [nTPM]":"25.4","Cell RNA - RH-30 [nTPM]":"20.2","Cell RNA - RPMI-8226 [nTPM]":"52.4","Cell RNA - RPTEC TERT1 [nTPM]":"49.2","Cell RNA - RT4 [nTPM]":"78.8","Cell RNA - SCLC-21H [nTPM]":"23.9","Cell RNA - SH-SY5Y [nTPM]":"21.9","Cell RNA - SiHa [nTPM]":"22.4","Cell RNA - SK-BR-3 [nTPM]":"121.7","Cell RNA - SK-MEL-30 [nTPM]":"29.0","Cell RNA - SuSa [nTPM]":"36.5","Cell RNA - T-47d [nTPM]":"33.9","Cell RNA - THP-1 [nTPM]":"75.3","Cell RNA - TIME [nTPM]":"26.1","Cell RNA - U-138 MG [nTPM]":"30.0","Cell RNA - U-2 OS [nTPM]":"19.7","Cell RNA - U-2197 [nTPM]":"22.9","Cell RNA - U-251 MG [nTPM]":"25.0","Cell RNA - U-266\/70 [nTPM]":"19.3","Cell RNA - U-266\/84 [nTPM]":"9.1","Cell RNA - U-698 [nTPM]":"15.3","Cell RNA - U-87 MG [nTPM]":"31.2","Cell RNA - U-937 [nTPM]":"42.8","Cell RNA - WM-115 [nTPM]":"29.9","Blood RNA - basophil [nTPM]":"1.5","Blood RNA - classical monocyte [nTPM]":"2.4","Blood RNA - eosinophil [nTPM]":"0.9","Blood RNA - gdT-cell [nTPM]":"4.6","Blood RNA - intermediate monocyte [nTPM]":"2.6","Blood RNA - MAIT T-cell [nTPM]":"3.0","Blood RNA - memory B-cell [nTPM]":"4.2","Blood RNA - memory CD4 T-cell [nTPM]":"5.5","Blood RNA - memory CD8 T-cell [nTPM]":"4.7","Blood RNA - myeloid DC [nTPM]":"4.5","Blood RNA - naive B-cell [nTPM]":"5.6","Blood RNA - naive CD4 T-cell [nTPM]":"4.5","Blood RNA - naive CD8 T-cell [nTPM]":"4.6","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"3.3","Blood RNA - non-classical monocyte [nTPM]":"2.1","Blood RNA - plasmacytoid DC [nTPM]":"4.4","Blood RNA - T-reg [nTPM]":"3.6","Blood RNA - total PBMC [nTPM]":"3.1","Brain RNA - amygdala [nTPM]":"40.0","Brain RNA - basal ganglia [nTPM]":"40.1","Brain RNA - cerebellum [nTPM]":"44.4","Brain RNA - cerebral cortex [nTPM]":"45.8","Brain RNA - hippocampal formation [nTPM]":"41.2","Brain RNA - hypothalamus [nTPM]":"37.7","Brain RNA - medulla oblongata [nTPM]":"47.0","Brain RNA - midbrain [nTPM]":"43.0","Brain RNA - pons [nTPM]":"47.3","Brain RNA - spinal cord [nTPM]":"41.3","Brain RNA - thalamus [nTPM]":"41.0","Brain RNA - white matter [nTPM]":"44.0","Single Cell Type RNA - Adipocytes [nTPM]":"11.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.3","Single Cell Type RNA - Astrocytes [nTPM]":"15.0","Single Cell Type RNA - B-cells [nTPM]":"11.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"12.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"62.9","Single Cell Type RNA - Club cells [nTPM]":"9.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"73.1","Single Cell Type RNA - dendritic cells [nTPM]":"21.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"41.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"119.3","Single Cell Type RNA - Ductal cells [nTPM]":"19.5","Single Cell Type RNA - Early spermatids [nTPM]":"763.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"29.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.5","Single Cell Type RNA - Endothelial cells [nTPM]":"8.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.9","Single Cell Type RNA - Erythroid cells [nTPM]":"47.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"39.7","Single Cell Type RNA - Fibroblasts [nTPM]":"7.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"36.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.8","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"39.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.8","Single Cell Type RNA - Hepatocytes [nTPM]":"166.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.1","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"29.1","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"11.8","Single Cell Type RNA - Langerhans cells [nTPM]":"3.3","Single Cell Type RNA - Late spermatids [nTPM]":"2829.0","Single Cell Type RNA - Leydig cells [nTPM]":"27.7","Single Cell Type RNA - Macrophages [nTPM]":"8.1","Single Cell Type RNA - Melanocytes [nTPM]":"33.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"14.7","Single Cell Type RNA - Muller glia cells [nTPM]":"26.7","Single Cell Type RNA - NK-cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.8","Single Cell Type RNA - Paneth cells [nTPM]":"18.8","Single Cell Type RNA - Peritubular cells [nTPM]":"25.9","Single Cell Type RNA - Plasma cells [nTPM]":"13.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"144.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"130.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.6","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.5","Single Cell Type RNA - Spermatocytes [nTPM]":"253.1","Single Cell Type RNA - Spermatogonia [nTPM]":"18.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"50.8","Single Cell Type RNA - T-cells [nTPM]":"13.6","Single Cell Type RNA - Theca cells [nTPM]":"34.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"48.7","Single Cell Type RNA - Urothelial cells [nTPM]":"7.7"},{"Gene":"PDE6G","Gene synonym":["PDEG","RP57"],"Ensembl":"ENSG00000185527","Gene description":"Phosphodiesterase 6G","Uniprot":["P18545"],"Chromosome":"17","Position":"81650459-81663112","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["Hydrolase"],"Disease involvement":["Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"99","RNA tissue specific nTPM":{"retina":"2050.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Rod photoreceptor cells":"4448.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"10.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"127.0","NK-cell":"220.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"127.0","NK-cells":"220.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"5.2","NB-4":"5.8","NTERA-2":"8.9","REH":"11.9","SuSa":"6.2"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hippocampal formation":"4.7"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045118"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA045118":"AB_2732517"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.5","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"4.7","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"7.8","Tissue RNA - breast [nTPM]":"0.9","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"1.0","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"1.6","Tissue RNA - duodenum [nTPM]":"0.6","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.8","Tissue RNA - fallopian tube [nTPM]":"0.7","Tissue RNA - gallbladder [nTPM]":"2.5","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.7","Tissue RNA - kidney [nTPM]":"2.1","Tissue RNA - liver [nTPM]":"4.2","Tissue RNA - lung [nTPM]":"3.0","Tissue RNA - lymph node [nTPM]":"20.6","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"12.0","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"1.0","Tissue RNA - retina [nTPM]":"2050.3","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"1.2","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"1.6","Tissue RNA - smooth muscle [nTPM]":"0.9","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"19.9","Tissue RNA - stomach 1 [nTPM]":"1.7","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"8.3","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"7.1","Tissue RNA - urinary bladder [nTPM]":"3.0","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.5","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.9","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"5.2","Cell RNA - HHSteC [nTPM]":"0.8","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.4","Cell RNA - HUVEC TERT2 [nTPM]":"2.8","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"5.8","Cell RNA - NTERA-2 [nTPM]":"8.9","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"11.9","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.9","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"6.2","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.8","Cell RNA - TIME [nTPM]":"1.2","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"0.9","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"3.1","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"127.0","Blood RNA - classical monocyte [nTPM]":"18.1","Blood RNA - eosinophil [nTPM]":"30.5","Blood RNA - gdT-cell [nTPM]":"4.1","Blood RNA - intermediate monocyte [nTPM]":"26.2","Blood RNA - MAIT T-cell [nTPM]":"1.3","Blood RNA - memory B-cell [nTPM]":"2.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"2.3","Blood RNA - myeloid DC [nTPM]":"28.9","Blood RNA - naive B-cell [nTPM]":"5.1","Blood RNA - naive CD4 T-cell [nTPM]":"2.1","Blood RNA - naive CD8 T-cell [nTPM]":"7.4","Blood RNA - neutrophil [nTPM]":"2.4","Blood RNA - NK-cell [nTPM]":"220.2","Blood RNA - non-classical monocyte [nTPM]":"15.5","Blood RNA - plasmacytoid DC [nTPM]":"2.9","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"13.5","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.7","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"422.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"517.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"4.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"27.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"23.6","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.9","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.6","Single Cell Type RNA - Horizontal cells [nTPM]":"262.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.8","Single Cell Type RNA - Langerhans cells [nTPM]":"8.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"4.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"13.3","Single Cell Type RNA - Muller glia cells [nTPM]":"709.0","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4448.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"1.7","Single Cell Type RNA - Theca cells [nTPM]":"2.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"PDE6H","Gene synonym":[],"Ensembl":"ENSG00000139053","Gene description":"Phosphodiesterase 6H","Uniprot":["Q13956"],"Chromosome":"12","Position":"14973042-14981865","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"226","RNA tissue specific nTPM":{"retina":"911.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"831.9","Rod photoreceptor cells":"218.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AN3-CA":"1.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045118"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA045118":"AB_2732517"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.4","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"4.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"1.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.9","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"2.3","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.9","Tissue RNA - pons [nTPM]":"0.5","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"911.3","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"1.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.7","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"1.0","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"2.3","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.5","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"62.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"831.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"3.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.8","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.9","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"81.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"218.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PDHA1","Gene synonym":["PDHA"],"Ensembl":"ENSG00000131828","Gene description":"Pyruvate dehydrogenase E1 subunit alpha 1","Uniprot":["P08559"],"Chromosome":"X","Position":"19343893-19361718","Protein class":["Citric acid cycle related proteins","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism","Glucose metabolism","Tricarboxylic acid cycle"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Leigh syndrome","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"508.8","tongue":"770.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"479.9","Distal tubular cells":"354.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047487","HPA047864","HPA063053"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"100000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA047487":"AB_2680066","HPA047864":"AB_2680190","HPA063053":"AB_2684931"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.13e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Tissue RNA - adipose tissue [nTPM]":"93.0","Tissue RNA - adrenal gland [nTPM]":"69.0","Tissue RNA - amygdala [nTPM]":"62.1","Tissue RNA - appendix [nTPM]":"37.9","Tissue RNA - basal ganglia [nTPM]":"66.9","Tissue RNA - bone marrow [nTPM]":"88.1","Tissue RNA - breast [nTPM]":"63.1","Tissue RNA - cerebellum [nTPM]":"66.2","Tissue RNA - cerebral cortex [nTPM]":"91.5","Tissue RNA - cervix [nTPM]":"55.9","Tissue RNA - choroid plexus [nTPM]":"84.4","Tissue RNA - colon [nTPM]":"112.6","Tissue RNA - duodenum [nTPM]":"87.0","Tissue RNA - endometrium 1 [nTPM]":"53.1","Tissue RNA - epididymis [nTPM]":"78.9","Tissue RNA - esophagus [nTPM]":"76.8","Tissue RNA - fallopian tube [nTPM]":"49.1","Tissue RNA - gallbladder [nTPM]":"29.3","Tissue RNA - heart muscle [nTPM]":"508.8","Tissue RNA - hippocampal formation [nTPM]":"68.2","Tissue RNA - hypothalamus [nTPM]":"67.0","Tissue RNA - kidney [nTPM]":"174.1","Tissue RNA - liver [nTPM]":"118.3","Tissue RNA - lung [nTPM]":"47.2","Tissue RNA - lymph node [nTPM]":"36.6","Tissue RNA - medulla oblongata [nTPM]":"64.5","Tissue RNA - midbrain [nTPM]":"62.7","Tissue RNA - ovary [nTPM]":"50.6","Tissue RNA - pancreas [nTPM]":"83.4","Tissue RNA - parathyroid gland [nTPM]":"161.0","Tissue RNA - pituitary gland [nTPM]":"48.7","Tissue RNA - placenta [nTPM]":"43.1","Tissue RNA - pons [nTPM]":"65.0","Tissue RNA - prostate [nTPM]":"48.4","Tissue RNA - rectum [nTPM]":"104.4","Tissue RNA - retina [nTPM]":"90.1","Tissue RNA - salivary gland [nTPM]":"109.7","Tissue RNA - seminal vesicle [nTPM]":"63.4","Tissue RNA - skeletal muscle [nTPM]":"459.0","Tissue RNA - skin 1 [nTPM]":"60.9","Tissue RNA - small intestine [nTPM]":"82.1","Tissue RNA - smooth muscle [nTPM]":"51.8","Tissue RNA - spinal cord [nTPM]":"59.6","Tissue RNA - spleen [nTPM]":"49.3","Tissue RNA - stomach 1 [nTPM]":"121.8","Tissue RNA - testis [nTPM]":"24.0","Tissue RNA - thalamus [nTPM]":"67.4","Tissue RNA - thymus [nTPM]":"52.3","Tissue RNA - thyroid gland [nTPM]":"64.5","Tissue RNA - tongue [nTPM]":"770.2","Tissue RNA - tonsil [nTPM]":"59.1","Tissue RNA - urinary bladder [nTPM]":"61.7","Tissue RNA - vagina [nTPM]":"56.1","Tissue RNA - white matter [nTPM]":"71.1","Cell RNA - A-431 [nTPM]":"124.9","Cell RNA - A549 [nTPM]":"151.4","Cell RNA - AF22 [nTPM]":"107.9","Cell RNA - AN3-CA [nTPM]":"114.2","Cell RNA - ASC diff [nTPM]":"102.3","Cell RNA - ASC TERT1 [nTPM]":"77.7","Cell RNA - BEWO [nTPM]":"131.6","Cell RNA - BJ [nTPM]":"83.8","Cell RNA - BJ hTERT+ [nTPM]":"74.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"170.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"130.7","Cell RNA - CACO-2 [nTPM]":"216.6","Cell RNA - CAPAN-2 [nTPM]":"78.2","Cell RNA - Daudi [nTPM]":"212.2","Cell RNA - EFO-21 [nTPM]":"60.6","Cell RNA - fHDF\/TERT166 [nTPM]":"102.0","Cell RNA - GAMG [nTPM]":"226.7","Cell RNA - HaCaT [nTPM]":"159.0","Cell RNA - HAP1 [nTPM]":"334.2","Cell RNA - HBEC3-KT [nTPM]":"145.8","Cell RNA - HBF TERT88 [nTPM]":"178.1","Cell RNA - HDLM-2 [nTPM]":"70.1","Cell RNA - HEK 293 [nTPM]":"186.1","Cell RNA - HEL [nTPM]":"104.8","Cell RNA - HeLa [nTPM]":"264.0","Cell RNA - Hep G2 [nTPM]":"194.2","Cell RNA - HHSteC [nTPM]":"107.8","Cell RNA - HL-60 [nTPM]":"170.3","Cell RNA - HMC-1 [nTPM]":"82.8","Cell RNA - HSkMC [nTPM]":"100.9","Cell RNA - hTCEpi [nTPM]":"132.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"157.3","Cell RNA - hTERT-HME1 [nTPM]":"154.4","Cell RNA - hTERT-RPE1 [nTPM]":"85.6","Cell RNA - HUVEC TERT2 [nTPM]":"105.3","Cell RNA - JURKAT [nTPM]":"129.8","Cell RNA - K-562 [nTPM]":"94.2","Cell RNA - Karpas-707 [nTPM]":"87.2","Cell RNA - LHCN-M2 [nTPM]":"120.7","Cell RNA - MCF7 [nTPM]":"164.5","Cell RNA - MOLT-4 [nTPM]":"142.7","Cell RNA - NB-4 [nTPM]":"173.5","Cell RNA - NTERA-2 [nTPM]":"110.0","Cell RNA - OE19 [nTPM]":"227.4","Cell RNA - PC-3 [nTPM]":"261.7","Cell RNA - REH [nTPM]":"145.2","Cell RNA - RH-30 [nTPM]":"180.9","Cell RNA - RPMI-8226 [nTPM]":"260.3","Cell RNA - RPTEC TERT1 [nTPM]":"298.0","Cell RNA - RT4 [nTPM]":"125.1","Cell RNA - SCLC-21H [nTPM]":"59.7","Cell RNA - SH-SY5Y [nTPM]":"62.6","Cell RNA - SiHa [nTPM]":"134.1","Cell RNA - SK-BR-3 [nTPM]":"167.8","Cell RNA - SK-MEL-30 [nTPM]":"158.1","Cell RNA - SuSa [nTPM]":"229.8","Cell RNA - T-47d [nTPM]":"177.1","Cell RNA - THP-1 [nTPM]":"118.1","Cell RNA - TIME [nTPM]":"65.4","Cell RNA - U-138 MG [nTPM]":"87.6","Cell RNA - U-2 OS [nTPM]":"78.6","Cell RNA - U-2197 [nTPM]":"240.9","Cell RNA - U-251 MG [nTPM]":"108.6","Cell RNA - U-266\/70 [nTPM]":"73.3","Cell RNA - U-266\/84 [nTPM]":"82.0","Cell RNA - U-698 [nTPM]":"140.5","Cell RNA - U-87 MG [nTPM]":"82.4","Cell RNA - U-937 [nTPM]":"117.2","Cell RNA - WM-115 [nTPM]":"77.4","Blood RNA - basophil [nTPM]":"99.9","Blood RNA - classical monocyte [nTPM]":"87.4","Blood RNA - eosinophil [nTPM]":"65.3","Blood RNA - gdT-cell [nTPM]":"72.3","Blood RNA - intermediate monocyte [nTPM]":"119.9","Blood RNA - MAIT T-cell [nTPM]":"88.9","Blood RNA - memory B-cell [nTPM]":"103.4","Blood RNA - memory CD4 T-cell [nTPM]":"69.4","Blood RNA - memory CD8 T-cell [nTPM]":"79.5","Blood RNA - myeloid DC [nTPM]":"115.7","Blood RNA - naive B-cell [nTPM]":"82.1","Blood RNA - naive CD4 T-cell [nTPM]":"67.7","Blood RNA - naive CD8 T-cell [nTPM]":"72.0","Blood RNA - neutrophil [nTPM]":"15.5","Blood RNA - NK-cell [nTPM]":"98.1","Blood RNA - non-classical monocyte [nTPM]":"109.1","Blood RNA - plasmacytoid DC [nTPM]":"76.9","Blood RNA - T-reg [nTPM]":"84.4","Blood RNA - total PBMC [nTPM]":"89.6","Brain RNA - amygdala [nTPM]":"62.1","Brain RNA - basal ganglia [nTPM]":"66.9","Brain RNA - cerebellum [nTPM]":"66.2","Brain RNA - cerebral cortex [nTPM]":"91.5","Brain RNA - hippocampal formation [nTPM]":"68.2","Brain RNA - hypothalamus [nTPM]":"67.0","Brain RNA - medulla oblongata [nTPM]":"64.5","Brain RNA - midbrain [nTPM]":"62.7","Brain RNA - pons [nTPM]":"65.0","Brain RNA - spinal cord [nTPM]":"59.6","Brain RNA - thalamus [nTPM]":"67.4","Brain RNA - white matter [nTPM]":"71.1","Single Cell Type RNA - Adipocytes [nTPM]":"34.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"44.4","Single Cell Type RNA - Astrocytes [nTPM]":"18.6","Single Cell Type RNA - B-cells [nTPM]":"30.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"29.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"59.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"135.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.0","Single Cell Type RNA - Bipolar cells [nTPM]":"59.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"37.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"29.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"479.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"87.2","Single Cell Type RNA - Club cells [nTPM]":"74.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"152.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"105.0","Single Cell Type RNA - dendritic cells [nTPM]":"32.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"73.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"354.1","Single Cell Type RNA - Ductal cells [nTPM]":"88.8","Single Cell Type RNA - Early spermatids [nTPM]":"2.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"41.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"33.7","Single Cell Type RNA - Endothelial cells [nTPM]":"36.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"41.9","Single Cell Type RNA - Erythroid cells [nTPM]":"55.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"21.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"59.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"120.7","Single Cell Type RNA - Fibroblasts [nTPM]":"49.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"49.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"36.9","Single Cell Type RNA - granulocytes [nTPM]":"42.6","Single Cell Type RNA - Granulosa cells [nTPM]":"39.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.2","Single Cell Type RNA - Hepatocytes [nTPM]":"76.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"73.2","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"64.4","Single Cell Type RNA - Ionocytes [nTPM]":"71.2","Single Cell Type RNA - Kupffer cells [nTPM]":"26.8","Single Cell Type RNA - Langerhans cells [nTPM]":"30.5","Single Cell Type RNA - Late spermatids [nTPM]":"4.1","Single Cell Type RNA - Leydig cells [nTPM]":"35.4","Single Cell Type RNA - Macrophages [nTPM]":"32.5","Single Cell Type RNA - Melanocytes [nTPM]":"56.9","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"40.8","Single Cell Type RNA - Muller glia cells [nTPM]":"49.0","Single Cell Type RNA - NK-cells [nTPM]":"26.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"47.4","Single Cell Type RNA - Paneth cells [nTPM]":"52.5","Single Cell Type RNA - Peritubular cells [nTPM]":"40.6","Single Cell Type RNA - Plasma cells [nTPM]":"43.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"47.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"88.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"213.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"69.1","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"37.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"51.7","Single Cell Type RNA - Spermatocytes [nTPM]":"51.1","Single Cell Type RNA - Spermatogonia [nTPM]":"25.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"45.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"33.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"133.4","Single Cell Type RNA - T-cells [nTPM]":"31.6","Single Cell Type RNA - Theca cells [nTPM]":"25.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"130.3","Single Cell Type RNA - Urothelial cells [nTPM]":"55.8"},{"Gene":"PDHB","Gene synonym":["PDHE1B"],"Ensembl":"ENSG00000168291","Gene description":"Pyruvate dehydrogenase E1 subunit beta","Uniprot":["P11177"],"Chromosome":"3","Position":"58427630-58433857","Protein class":["Citric acid cycle related proteins","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism","Glucose metabolism","Tricarboxylic acid cycle"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"tongue":"299.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"300.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033794","HPA036744","HPA036745"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"61000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB033794":"AB_2162946","HPA036744":"AB_10670921","HPA036745":"AB_2675285"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.79e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-2"},"Tissue RNA - adipose tissue [nTPM]":"59.9","Tissue RNA - adrenal gland [nTPM]":"76.5","Tissue RNA - amygdala [nTPM]":"48.7","Tissue RNA - appendix [nTPM]":"42.2","Tissue RNA - basal ganglia [nTPM]":"50.2","Tissue RNA - bone marrow [nTPM]":"25.7","Tissue RNA - breast [nTPM]":"42.9","Tissue RNA - cerebellum [nTPM]":"53.9","Tissue RNA - cerebral cortex [nTPM]":"62.7","Tissue RNA - cervix [nTPM]":"43.3","Tissue RNA - choroid plexus [nTPM]":"63.6","Tissue RNA - colon [nTPM]":"56.8","Tissue RNA - duodenum [nTPM]":"42.5","Tissue RNA - endometrium 1 [nTPM]":"38.5","Tissue RNA - epididymis [nTPM]":"44.6","Tissue RNA - esophagus [nTPM]":"57.4","Tissue RNA - fallopian tube [nTPM]":"37.7","Tissue RNA - gallbladder [nTPM]":"35.9","Tissue RNA - heart muscle [nTPM]":"175.0","Tissue RNA - hippocampal formation [nTPM]":"49.7","Tissue RNA - hypothalamus [nTPM]":"52.3","Tissue RNA - kidney [nTPM]":"100.8","Tissue RNA - liver [nTPM]":"110.7","Tissue RNA - lung [nTPM]":"36.4","Tissue RNA - lymph node [nTPM]":"53.1","Tissue RNA - medulla oblongata [nTPM]":"51.7","Tissue RNA - midbrain [nTPM]":"49.4","Tissue RNA - ovary [nTPM]":"26.5","Tissue RNA - pancreas [nTPM]":"36.4","Tissue RNA - parathyroid gland [nTPM]":"88.8","Tissue RNA - pituitary gland [nTPM]":"44.1","Tissue RNA - placenta [nTPM]":"57.0","Tissue RNA - pons [nTPM]":"51.5","Tissue RNA - prostate [nTPM]":"48.5","Tissue RNA - rectum [nTPM]":"60.4","Tissue RNA - retina [nTPM]":"30.7","Tissue RNA - salivary gland [nTPM]":"45.9","Tissue RNA - seminal vesicle [nTPM]":"52.1","Tissue RNA - skeletal muscle [nTPM]":"272.6","Tissue RNA - skin 1 [nTPM]":"36.8","Tissue RNA - small intestine [nTPM]":"37.6","Tissue RNA - smooth muscle [nTPM]":"63.8","Tissue RNA - spinal cord [nTPM]":"51.6","Tissue RNA - spleen [nTPM]":"42.8","Tissue RNA - stomach 1 [nTPM]":"53.9","Tissue RNA - testis [nTPM]":"42.3","Tissue RNA - thalamus [nTPM]":"53.1","Tissue RNA - thymus [nTPM]":"53.1","Tissue RNA - thyroid gland [nTPM]":"40.8","Tissue RNA - tongue [nTPM]":"299.4","Tissue RNA - tonsil [nTPM]":"56.0","Tissue RNA - urinary bladder [nTPM]":"49.7","Tissue RNA - vagina [nTPM]":"35.9","Tissue RNA - white matter [nTPM]":"54.3","Cell RNA - A-431 [nTPM]":"66.5","Cell RNA - A549 [nTPM]":"90.9","Cell RNA - AF22 [nTPM]":"92.3","Cell RNA - AN3-CA [nTPM]":"69.8","Cell RNA - ASC diff [nTPM]":"91.7","Cell RNA - ASC TERT1 [nTPM]":"111.1","Cell RNA - BEWO [nTPM]":"110.4","Cell RNA - BJ [nTPM]":"81.6","Cell RNA - BJ hTERT+ [nTPM]":"101.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"117.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"120.6","Cell RNA - CACO-2 [nTPM]":"165.1","Cell RNA - CAPAN-2 [nTPM]":"62.6","Cell RNA - Daudi [nTPM]":"140.3","Cell RNA - EFO-21 [nTPM]":"44.9","Cell RNA - fHDF\/TERT166 [nTPM]":"103.8","Cell RNA - GAMG [nTPM]":"109.0","Cell RNA - HaCaT [nTPM]":"37.6","Cell RNA - HAP1 [nTPM]":"113.2","Cell RNA - HBEC3-KT [nTPM]":"74.9","Cell RNA - HBF TERT88 [nTPM]":"90.0","Cell RNA - HDLM-2 [nTPM]":"81.7","Cell RNA - HEK 293 [nTPM]":"83.0","Cell RNA - HEL [nTPM]":"125.4","Cell RNA - HeLa [nTPM]":"163.7","Cell RNA - Hep G2 [nTPM]":"126.0","Cell RNA - HHSteC [nTPM]":"92.5","Cell RNA - HL-60 [nTPM]":"103.0","Cell RNA - HMC-1 [nTPM]":"67.9","Cell RNA - HSkMC [nTPM]":"97.9","Cell RNA - hTCEpi [nTPM]":"67.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"95.5","Cell RNA - hTERT-HME1 [nTPM]":"55.8","Cell RNA - hTERT-RPE1 [nTPM]":"137.5","Cell RNA - HUVEC TERT2 [nTPM]":"103.1","Cell RNA - JURKAT [nTPM]":"114.2","Cell RNA - K-562 [nTPM]":"65.9","Cell RNA - Karpas-707 [nTPM]":"61.5","Cell RNA - LHCN-M2 [nTPM]":"129.5","Cell RNA - MCF7 [nTPM]":"63.1","Cell RNA - MOLT-4 [nTPM]":"98.2","Cell RNA - NB-4 [nTPM]":"107.8","Cell RNA - NTERA-2 [nTPM]":"127.2","Cell RNA - OE19 [nTPM]":"69.2","Cell RNA - PC-3 [nTPM]":"101.3","Cell RNA - REH [nTPM]":"46.3","Cell RNA - RH-30 [nTPM]":"71.8","Cell RNA - RPMI-8226 [nTPM]":"136.1","Cell RNA - RPTEC TERT1 [nTPM]":"188.1","Cell RNA - RT4 [nTPM]":"89.1","Cell RNA - SCLC-21H [nTPM]":"63.7","Cell RNA - SH-SY5Y [nTPM]":"70.2","Cell RNA - SiHa [nTPM]":"75.6","Cell RNA - SK-BR-3 [nTPM]":"107.2","Cell RNA - SK-MEL-30 [nTPM]":"85.4","Cell RNA - SuSa [nTPM]":"131.3","Cell RNA - T-47d [nTPM]":"159.0","Cell RNA - THP-1 [nTPM]":"108.7","Cell RNA - TIME [nTPM]":"76.3","Cell RNA - U-138 MG [nTPM]":"62.9","Cell RNA - U-2 OS [nTPM]":"83.7","Cell RNA - U-2197 [nTPM]":"66.8","Cell RNA - U-251 MG [nTPM]":"94.2","Cell RNA - U-266\/70 [nTPM]":"85.2","Cell RNA - U-266\/84 [nTPM]":"129.9","Cell RNA - U-698 [nTPM]":"99.2","Cell RNA - U-87 MG [nTPM]":"96.2","Cell RNA - U-937 [nTPM]":"120.8","Cell RNA - WM-115 [nTPM]":"60.7","Blood RNA - basophil [nTPM]":"57.8","Blood RNA - classical monocyte [nTPM]":"98.9","Blood RNA - eosinophil [nTPM]":"98.7","Blood RNA - gdT-cell [nTPM]":"83.2","Blood RNA - intermediate monocyte [nTPM]":"115.1","Blood RNA - MAIT T-cell [nTPM]":"87.9","Blood RNA - memory B-cell [nTPM]":"102.2","Blood RNA - memory CD4 T-cell [nTPM]":"81.7","Blood RNA - memory CD8 T-cell [nTPM]":"80.5","Blood RNA - myeloid DC [nTPM]":"141.1","Blood RNA - naive B-cell [nTPM]":"103.4","Blood RNA - naive CD4 T-cell [nTPM]":"90.9","Blood RNA - naive CD8 T-cell [nTPM]":"82.4","Blood RNA - neutrophil [nTPM]":"19.6","Blood RNA - NK-cell [nTPM]":"129.4","Blood RNA - non-classical monocyte [nTPM]":"109.7","Blood RNA - plasmacytoid DC [nTPM]":"94.7","Blood RNA - T-reg [nTPM]":"113.2","Blood RNA - total PBMC [nTPM]":"124.1","Brain RNA - amygdala [nTPM]":"48.7","Brain RNA - basal ganglia [nTPM]":"50.2","Brain RNA - cerebellum [nTPM]":"53.9","Brain RNA - cerebral cortex [nTPM]":"62.7","Brain RNA - hippocampal formation [nTPM]":"49.7","Brain RNA - hypothalamus [nTPM]":"52.3","Brain RNA - medulla oblongata [nTPM]":"51.7","Brain RNA - midbrain [nTPM]":"49.4","Brain RNA - pons [nTPM]":"51.5","Brain RNA - spinal cord [nTPM]":"51.6","Brain RNA - thalamus [nTPM]":"53.1","Brain RNA - white matter [nTPM]":"54.3","Single Cell Type RNA - Adipocytes [nTPM]":"57.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"34.5","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"45.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"27.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"40.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"142.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.7","Single Cell Type RNA - Bipolar cells [nTPM]":"31.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"31.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"300.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"48.6","Single Cell Type RNA - Club cells [nTPM]":"96.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"35.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"174.1","Single Cell Type RNA - dendritic cells [nTPM]":"35.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"41.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"230.9","Single Cell Type RNA - Ductal cells [nTPM]":"95.9","Single Cell Type RNA - Early spermatids [nTPM]":"76.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"37.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"37.3","Single Cell Type RNA - Endothelial cells [nTPM]":"58.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"58.0","Single Cell Type RNA - Erythroid cells [nTPM]":"22.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"72.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"101.6","Single Cell Type RNA - Fibroblasts [nTPM]":"54.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"29.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"34.2","Single Cell Type RNA - granulocytes [nTPM]":"39.3","Single Cell Type RNA - Granulosa cells [nTPM]":"48.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"46.1","Single Cell Type RNA - Hepatocytes [nTPM]":"76.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"84.6","Single Cell Type RNA - Horizontal cells [nTPM]":"57.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"50.4","Single Cell Type RNA - Ionocytes [nTPM]":"162.8","Single Cell Type RNA - Kupffer cells [nTPM]":"37.9","Single Cell Type RNA - Langerhans cells [nTPM]":"26.6","Single Cell Type RNA - Late spermatids [nTPM]":"16.9","Single Cell Type RNA - Leydig cells [nTPM]":"60.3","Single Cell Type RNA - Macrophages [nTPM]":"37.2","Single Cell Type RNA - Melanocytes [nTPM]":"56.9","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"76.5","Single Cell Type RNA - Muller glia cells [nTPM]":"61.7","Single Cell Type RNA - NK-cells [nTPM]":"70.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"13.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"55.9","Single Cell Type RNA - Paneth cells [nTPM]":"43.0","Single Cell Type RNA - Peritubular cells [nTPM]":"51.1","Single Cell Type RNA - Plasma cells [nTPM]":"38.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"45.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"146.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"70.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"72.3","Single Cell Type RNA - Spermatocytes [nTPM]":"98.2","Single Cell Type RNA - Spermatogonia [nTPM]":"88.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"42.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"29.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"157.2","Single Cell Type RNA - T-cells [nTPM]":"44.7","Single Cell Type RNA - Theca cells [nTPM]":"224.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"53.0","Single Cell Type RNA - Urothelial cells [nTPM]":"37.7"},{"Gene":"PDK3","Gene synonym":[],"Ensembl":"ENSG00000067992","Gene description":"Pyruvate dehydrogenase kinase 3","Uniprot":["Q15120"],"Chromosome":"X","Position":"24465270-24550466","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism","Glucose metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"71.6","Excitatory neurons":"92.8","Inhibitory neurons":"78.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046583","HPA072492"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA046583":"AB_2679707","HPA072492":"AB_2686526"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.76e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.43e-3"},"Tissue RNA - adipose tissue [nTPM]":"4.4","Tissue RNA - adrenal gland [nTPM]":"2.0","Tissue RNA - amygdala [nTPM]":"4.4","Tissue RNA - appendix [nTPM]":"5.6","Tissue RNA - basal ganglia [nTPM]":"6.2","Tissue RNA - bone marrow [nTPM]":"8.9","Tissue RNA - breast [nTPM]":"8.8","Tissue RNA - cerebellum [nTPM]":"1.4","Tissue RNA - cerebral cortex [nTPM]":"7.5","Tissue RNA - cervix [nTPM]":"3.5","Tissue RNA - choroid plexus [nTPM]":"2.5","Tissue RNA - colon [nTPM]":"6.1","Tissue RNA - duodenum [nTPM]":"8.2","Tissue RNA - endometrium 1 [nTPM]":"2.8","Tissue RNA - epididymis [nTPM]":"10.9","Tissue RNA - esophagus [nTPM]":"3.9","Tissue RNA - fallopian tube [nTPM]":"5.9","Tissue RNA - gallbladder [nTPM]":"3.2","Tissue RNA - heart muscle [nTPM]":"7.4","Tissue RNA - hippocampal formation [nTPM]":"13.2","Tissue RNA - hypothalamus [nTPM]":"4.7","Tissue RNA - kidney [nTPM]":"8.8","Tissue RNA - liver [nTPM]":"4.7","Tissue RNA - lung [nTPM]":"5.0","Tissue RNA - lymph node [nTPM]":"7.9","Tissue RNA - medulla oblongata [nTPM]":"2.6","Tissue RNA - midbrain [nTPM]":"4.2","Tissue RNA - ovary [nTPM]":"4.8","Tissue RNA - pancreas [nTPM]":"2.9","Tissue RNA - parathyroid gland [nTPM]":"6.7","Tissue RNA - pituitary gland [nTPM]":"5.8","Tissue RNA - placenta [nTPM]":"4.1","Tissue RNA - pons [nTPM]":"2.4","Tissue RNA - prostate [nTPM]":"4.6","Tissue RNA - rectum [nTPM]":"5.3","Tissue RNA - retina [nTPM]":"6.0","Tissue RNA - salivary gland [nTPM]":"11.1","Tissue RNA - seminal vesicle [nTPM]":"2.9","Tissue RNA - skeletal muscle [nTPM]":"1.4","Tissue RNA - skin 1 [nTPM]":"6.8","Tissue RNA - small intestine [nTPM]":"8.3","Tissue RNA - smooth muscle [nTPM]":"4.5","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"7.7","Tissue RNA - stomach 1 [nTPM]":"6.9","Tissue RNA - testis [nTPM]":"11.6","Tissue RNA - thalamus [nTPM]":"9.1","Tissue RNA - thymus [nTPM]":"6.3","Tissue RNA - thyroid gland [nTPM]":"2.3","Tissue RNA - tongue [nTPM]":"1.8","Tissue RNA - tonsil [nTPM]":"8.0","Tissue RNA - urinary bladder [nTPM]":"4.2","Tissue RNA - vagina [nTPM]":"4.1","Tissue RNA - white matter [nTPM]":"4.2","Cell RNA - A-431 [nTPM]":"11.5","Cell RNA - A549 [nTPM]":"5.2","Cell RNA - AF22 [nTPM]":"4.2","Cell RNA - AN3-CA [nTPM]":"8.0","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"5.0","Cell RNA - BJ [nTPM]":"3.4","Cell RNA - BJ hTERT+ [nTPM]":"2.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.9","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"13.9","Cell RNA - Daudi [nTPM]":"10.4","Cell RNA - EFO-21 [nTPM]":"2.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.8","Cell RNA - GAMG [nTPM]":"11.6","Cell RNA - HaCaT [nTPM]":"2.1","Cell RNA - HAP1 [nTPM]":"12.3","Cell RNA - HBEC3-KT [nTPM]":"8.4","Cell RNA - HBF TERT88 [nTPM]":"10.4","Cell RNA - HDLM-2 [nTPM]":"9.7","Cell RNA - HEK 293 [nTPM]":"6.0","Cell RNA - HEL [nTPM]":"5.3","Cell RNA - HeLa [nTPM]":"6.1","Cell RNA - Hep G2 [nTPM]":"3.3","Cell RNA - HHSteC [nTPM]":"1.4","Cell RNA - HL-60 [nTPM]":"4.6","Cell RNA - HMC-1 [nTPM]":"5.8","Cell RNA - HSkMC [nTPM]":"0.9","Cell RNA - hTCEpi [nTPM]":"3.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.1","Cell RNA - hTERT-HME1 [nTPM]":"1.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.5","Cell RNA - HUVEC TERT2 [nTPM]":"6.8","Cell RNA - JURKAT [nTPM]":"10.9","Cell RNA - K-562 [nTPM]":"0.9","Cell RNA - Karpas-707 [nTPM]":"16.5","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"20.9","Cell RNA - MOLT-4 [nTPM]":"9.4","Cell RNA - NB-4 [nTPM]":"6.0","Cell RNA - NTERA-2 [nTPM]":"8.1","Cell RNA - OE19 [nTPM]":"12.2","Cell RNA - PC-3 [nTPM]":"5.6","Cell RNA - REH [nTPM]":"5.0","Cell RNA - RH-30 [nTPM]":"8.0","Cell RNA - RPMI-8226 [nTPM]":"17.3","Cell RNA - RPTEC TERT1 [nTPM]":"4.1","Cell RNA - RT4 [nTPM]":"21.4","Cell RNA - SCLC-21H [nTPM]":"2.6","Cell RNA - SH-SY5Y [nTPM]":"4.0","Cell RNA - SiHa [nTPM]":"17.9","Cell RNA - SK-BR-3 [nTPM]":"8.0","Cell RNA - SK-MEL-30 [nTPM]":"5.5","Cell RNA - SuSa [nTPM]":"7.3","Cell RNA - T-47d [nTPM]":"9.6","Cell RNA - THP-1 [nTPM]":"1.9","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"3.3","Cell RNA - U-2 OS [nTPM]":"3.6","Cell RNA - U-2197 [nTPM]":"5.8","Cell RNA - U-251 MG [nTPM]":"4.2","Cell RNA - U-266\/70 [nTPM]":"11.0","Cell RNA - U-266\/84 [nTPM]":"8.9","Cell RNA - U-698 [nTPM]":"12.9","Cell RNA - U-87 MG [nTPM]":"8.7","Cell RNA - U-937 [nTPM]":"7.7","Cell RNA - WM-115 [nTPM]":"6.4","Blood RNA - basophil [nTPM]":"13.3","Blood RNA - classical monocyte [nTPM]":"15.4","Blood RNA - eosinophil [nTPM]":"37.9","Blood RNA - gdT-cell [nTPM]":"11.8","Blood RNA - intermediate monocyte [nTPM]":"19.6","Blood RNA - MAIT T-cell [nTPM]":"16.5","Blood RNA - memory B-cell [nTPM]":"7.5","Blood RNA - memory CD4 T-cell [nTPM]":"9.1","Blood RNA - memory CD8 T-cell [nTPM]":"10.3","Blood RNA - myeloid DC [nTPM]":"12.2","Blood RNA - naive B-cell [nTPM]":"7.3","Blood RNA - naive CD4 T-cell [nTPM]":"7.6","Blood RNA - naive CD8 T-cell [nTPM]":"8.6","Blood RNA - neutrophil [nTPM]":"57.6","Blood RNA - NK-cell [nTPM]":"13.3","Blood RNA - non-classical monocyte [nTPM]":"18.8","Blood RNA - plasmacytoid DC [nTPM]":"3.5","Blood RNA - T-reg [nTPM]":"8.3","Blood RNA - total PBMC [nTPM]":"12.4","Brain RNA - amygdala [nTPM]":"4.4","Brain RNA - basal ganglia [nTPM]":"6.2","Brain RNA - cerebellum [nTPM]":"1.4","Brain RNA - cerebral cortex [nTPM]":"7.5","Brain RNA - hippocampal formation [nTPM]":"13.2","Brain RNA - hypothalamus [nTPM]":"4.7","Brain RNA - medulla oblongata [nTPM]":"2.6","Brain RNA - midbrain [nTPM]":"4.2","Brain RNA - pons [nTPM]":"2.4","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"9.1","Brain RNA - white matter [nTPM]":"4.2","Single Cell Type RNA - Adipocytes [nTPM]":"3.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.0","Single Cell Type RNA - Astrocytes [nTPM]":"19.6","Single Cell Type RNA - B-cells [nTPM]":"15.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"30.1","Single Cell Type RNA - Bipolar cells [nTPM]":"3.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"5.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.5","Single Cell Type RNA - dendritic cells [nTPM]":"16.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.3","Single Cell Type RNA - Early spermatids [nTPM]":"71.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.9","Single Cell Type RNA - Endothelial cells [nTPM]":"3.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"14.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"92.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"32.1","Single Cell Type RNA - Fibroblasts [nTPM]":"4.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.8","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"4.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"5.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.0","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"78.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.9","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"19.8","Single Cell Type RNA - Langerhans cells [nTPM]":"7.4","Single Cell Type RNA - Late spermatids [nTPM]":"35.9","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"17.4","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"35.6","Single Cell Type RNA - monocytes [nTPM]":"10.3","Single Cell Type RNA - Muller glia cells [nTPM]":"3.7","Single Cell Type RNA - NK-cells [nTPM]":"25.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"5.7","Single Cell Type RNA - Plasma cells [nTPM]":"19.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.6","Single Cell Type RNA - Spermatocytes [nTPM]":"10.2","Single Cell Type RNA - Spermatogonia [nTPM]":"8.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.8","Single Cell Type RNA - T-cells [nTPM]":"18.2","Single Cell Type RNA - Theca cells [nTPM]":"9.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.1","Single Cell Type RNA - Urothelial cells [nTPM]":"8.4"},{"Gene":"PDP1","Gene synonym":["PDH","PDP","PPM2A","PPM2C"],"Ensembl":"ENSG00000164951","Gene description":"Pyruvate dehyrogenase phosphatase catalytic subunit 1","Uniprot":["Q9P0J1"],"Chromosome":"8","Position":"93857807-93926068","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"80.0","Early spermatids":"144.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"8","RNA brain regional specific nTPM":{"amygdala":"14.2","basal ganglia":"20.1","cerebral cortex":"41.7","hippocampal formation":"23.4","white matter":"18.5"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"GAMG":"117.8","hTERT-RPE1":"117.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018483","HPA019081","HPA021152"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Mitochondria","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA018483":"AB_1855634","HPA019081":"AB_1855633","HPA021152":"AB_1855635"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.61e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.60e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.42e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.6","Tissue RNA - adrenal gland [nTPM]":"62.6","Tissue RNA - amygdala [nTPM]":"14.2","Tissue RNA - appendix [nTPM]":"10.5","Tissue RNA - basal ganglia [nTPM]":"20.1","Tissue RNA - bone marrow [nTPM]":"14.4","Tissue RNA - breast [nTPM]":"16.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"41.7","Tissue RNA - cervix [nTPM]":"14.2","Tissue RNA - choroid plexus [nTPM]":"1.2","Tissue RNA - colon [nTPM]":"8.9","Tissue RNA - duodenum [nTPM]":"7.2","Tissue RNA - endometrium 1 [nTPM]":"15.5","Tissue RNA - epididymis [nTPM]":"17.0","Tissue RNA - esophagus [nTPM]":"14.2","Tissue RNA - fallopian tube [nTPM]":"12.2","Tissue RNA - gallbladder [nTPM]":"19.4","Tissue RNA - heart muscle [nTPM]":"49.2","Tissue RNA - hippocampal formation [nTPM]":"23.4","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"12.8","Tissue RNA - liver [nTPM]":"4.2","Tissue RNA - lung [nTPM]":"12.6","Tissue RNA - lymph node [nTPM]":"12.9","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"2.3","Tissue RNA - ovary [nTPM]":"19.3","Tissue RNA - pancreas [nTPM]":"19.9","Tissue RNA - parathyroid gland [nTPM]":"29.9","Tissue RNA - pituitary gland [nTPM]":"5.4","Tissue RNA - placenta [nTPM]":"13.8","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"10.3","Tissue RNA - rectum [nTPM]":"12.4","Tissue RNA - retina [nTPM]":"14.1","Tissue RNA - salivary gland [nTPM]":"11.7","Tissue RNA - seminal vesicle [nTPM]":"9.4","Tissue RNA - skeletal muscle [nTPM]":"72.9","Tissue RNA - skin 1 [nTPM]":"4.3","Tissue RNA - small intestine [nTPM]":"7.6","Tissue RNA - smooth muscle [nTPM]":"11.2","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"13.2","Tissue RNA - stomach 1 [nTPM]":"11.7","Tissue RNA - testis [nTPM]":"26.7","Tissue RNA - thalamus [nTPM]":"3.0","Tissue RNA - thymus [nTPM]":"11.6","Tissue RNA - thyroid gland [nTPM]":"18.8","Tissue RNA - tongue [nTPM]":"16.9","Tissue RNA - tonsil [nTPM]":"12.4","Tissue RNA - urinary bladder [nTPM]":"14.0","Tissue RNA - vagina [nTPM]":"6.8","Tissue RNA - white matter [nTPM]":"18.5","Cell RNA - A-431 [nTPM]":"25.7","Cell RNA - A549 [nTPM]":"12.0","Cell RNA - AF22 [nTPM]":"25.9","Cell RNA - AN3-CA [nTPM]":"10.9","Cell RNA - ASC diff [nTPM]":"21.0","Cell RNA - ASC TERT1 [nTPM]":"37.9","Cell RNA - BEWO [nTPM]":"8.6","Cell RNA - BJ [nTPM]":"19.3","Cell RNA - BJ hTERT+ [nTPM]":"21.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"22.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"25.8","Cell RNA - CACO-2 [nTPM]":"12.7","Cell RNA - CAPAN-2 [nTPM]":"90.3","Cell RNA - Daudi [nTPM]":"13.9","Cell RNA - EFO-21 [nTPM]":"63.8","Cell RNA - fHDF\/TERT166 [nTPM]":"30.8","Cell RNA - GAMG [nTPM]":"117.8","Cell RNA - HaCaT [nTPM]":"54.4","Cell RNA - HAP1 [nTPM]":"11.0","Cell RNA - HBEC3-KT [nTPM]":"16.1","Cell RNA - HBF TERT88 [nTPM]":"32.8","Cell RNA - HDLM-2 [nTPM]":"1.5","Cell RNA - HEK 293 [nTPM]":"5.6","Cell RNA - HEL [nTPM]":"6.6","Cell RNA - HeLa [nTPM]":"15.7","Cell RNA - Hep G2 [nTPM]":"4.5","Cell RNA - HHSteC [nTPM]":"23.9","Cell RNA - HL-60 [nTPM]":"3.3","Cell RNA - HMC-1 [nTPM]":"9.0","Cell RNA - HSkMC [nTPM]":"24.5","Cell RNA - hTCEpi [nTPM]":"31.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"37.7","Cell RNA - hTERT-HME1 [nTPM]":"59.8","Cell RNA - hTERT-RPE1 [nTPM]":"117.1","Cell RNA - HUVEC TERT2 [nTPM]":"50.9","Cell RNA - JURKAT [nTPM]":"12.4","Cell RNA - K-562 [nTPM]":"2.4","Cell RNA - Karpas-707 [nTPM]":"22.8","Cell RNA - LHCN-M2 [nTPM]":"27.6","Cell RNA - MCF7 [nTPM]":"6.0","Cell RNA - MOLT-4 [nTPM]":"20.3","Cell RNA - NB-4 [nTPM]":"10.3","Cell RNA - NTERA-2 [nTPM]":"12.1","Cell RNA - OE19 [nTPM]":"26.8","Cell RNA - PC-3 [nTPM]":"15.4","Cell RNA - REH [nTPM]":"4.8","Cell RNA - RH-30 [nTPM]":"15.5","Cell RNA - RPMI-8226 [nTPM]":"2.6","Cell RNA - RPTEC TERT1 [nTPM]":"15.3","Cell RNA - RT4 [nTPM]":"17.0","Cell RNA - SCLC-21H [nTPM]":"2.4","Cell RNA - SH-SY5Y [nTPM]":"11.4","Cell RNA - SiHa [nTPM]":"12.7","Cell RNA - SK-BR-3 [nTPM]":"1.4","Cell RNA - SK-MEL-30 [nTPM]":"61.8","Cell RNA - SuSa [nTPM]":"20.9","Cell RNA - T-47d [nTPM]":"4.0","Cell RNA - THP-1 [nTPM]":"3.9","Cell RNA - TIME [nTPM]":"90.9","Cell RNA - U-138 MG [nTPM]":"27.5","Cell RNA - U-2 OS [nTPM]":"17.2","Cell RNA - U-2197 [nTPM]":"63.8","Cell RNA - U-251 MG [nTPM]":"23.3","Cell RNA - U-266\/70 [nTPM]":"12.6","Cell RNA - U-266\/84 [nTPM]":"5.8","Cell RNA - U-698 [nTPM]":"12.1","Cell RNA - U-87 MG [nTPM]":"34.2","Cell RNA - U-937 [nTPM]":"11.7","Cell RNA - WM-115 [nTPM]":"25.1","Blood RNA - basophil [nTPM]":"6.4","Blood RNA - classical monocyte [nTPM]":"27.9","Blood RNA - eosinophil [nTPM]":"14.5","Blood RNA - gdT-cell [nTPM]":"9.2","Blood RNA - intermediate monocyte [nTPM]":"25.3","Blood RNA - MAIT T-cell [nTPM]":"8.9","Blood RNA - memory B-cell [nTPM]":"15.6","Blood RNA - memory CD4 T-cell [nTPM]":"15.1","Blood RNA - memory CD8 T-cell [nTPM]":"12.0","Blood RNA - myeloid DC [nTPM]":"22.5","Blood RNA - naive B-cell [nTPM]":"17.9","Blood RNA - naive CD4 T-cell [nTPM]":"8.9","Blood RNA - naive CD8 T-cell [nTPM]":"7.8","Blood RNA - neutrophil [nTPM]":"3.1","Blood RNA - NK-cell [nTPM]":"5.4","Blood RNA - non-classical monocyte [nTPM]":"41.1","Blood RNA - plasmacytoid DC [nTPM]":"3.7","Blood RNA - T-reg [nTPM]":"34.9","Blood RNA - total PBMC [nTPM]":"18.0","Brain RNA - amygdala [nTPM]":"14.2","Brain RNA - basal ganglia [nTPM]":"20.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"41.7","Brain RNA - hippocampal formation [nTPM]":"23.4","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"2.3","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"3.0","Brain RNA - white matter [nTPM]":"18.5","Single Cell Type RNA - Adipocytes [nTPM]":"10.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.8","Single Cell Type RNA - Astrocytes [nTPM]":"15.0","Single Cell Type RNA - B-cells [nTPM]":"18.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"36.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"68.9","Single Cell Type RNA - Bipolar cells [nTPM]":"38.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"80.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"35.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.3","Single Cell Type RNA - dendritic cells [nTPM]":"13.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"27.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"33.3","Single Cell Type RNA - Early spermatids [nTPM]":"144.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"33.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.9","Single Cell Type RNA - Endothelial cells [nTPM]":"15.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.2","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"73.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.9","Single Cell Type RNA - Fibroblasts [nTPM]":"20.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"70.2","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"3.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.5","Single Cell Type RNA - Hepatocytes [nTPM]":"3.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.3","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"23.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.5","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"19.2","Single Cell Type RNA - Langerhans cells [nTPM]":"19.1","Single Cell Type RNA - Late spermatids [nTPM]":"28.1","Single Cell Type RNA - Leydig cells [nTPM]":"11.5","Single Cell Type RNA - Macrophages [nTPM]":"19.9","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"22.4","Single Cell Type RNA - Muller glia cells [nTPM]":"18.8","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"24.5","Single Cell Type RNA - Paneth cells [nTPM]":"9.6","Single Cell Type RNA - Peritubular cells [nTPM]":"13.5","Single Cell Type RNA - Plasma cells [nTPM]":"8.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"30.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"35.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.1","Single Cell Type RNA - Spermatocytes [nTPM]":"10.1","Single Cell Type RNA - Spermatogonia [nTPM]":"11.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.4","Single Cell Type RNA - T-cells [nTPM]":"19.3","Single Cell Type RNA - Theca cells [nTPM]":"7.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.7","Single Cell Type RNA - Urothelial cells [nTPM]":"23.9"},{"Gene":"PDSS1","Gene synonym":["COQ1","COQ1A","TPRT","TPT"],"Ensembl":"ENSG00000148459","Gene description":"Decaprenyl diphosphate synthase subunit 1","Uniprot":["Q5T2R2"],"Chromosome":"10","Position":"26697701-26746798","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Isoprene biosynthesis","Ubiquinone biosynthesis"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"19.1","lymphoid tissue":"13.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"32.5","Proximal enterocytes":"29.8","Undifferentiated cells":"29.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038032","HPA042741"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA038032":"AB_10670650","HPA042741":"AB_2678139"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.92e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.66e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.25e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.1","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"0.8","Tissue RNA - appendix [nTPM]":"5.3","Tissue RNA - basal ganglia [nTPM]":"0.9","Tissue RNA - bone marrow [nTPM]":"5.8","Tissue RNA - breast [nTPM]":"2.3","Tissue RNA - cerebellum [nTPM]":"2.6","Tissue RNA - cerebral cortex [nTPM]":"1.4","Tissue RNA - cervix [nTPM]":"1.8","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"14.1","Tissue RNA - duodenum [nTPM]":"19.1","Tissue RNA - endometrium 1 [nTPM]":"1.9","Tissue RNA - epididymis [nTPM]":"1.3","Tissue RNA - esophagus [nTPM]":"4.3","Tissue RNA - fallopian tube [nTPM]":"1.5","Tissue RNA - gallbladder [nTPM]":"1.6","Tissue RNA - heart muscle [nTPM]":"2.8","Tissue RNA - hippocampal formation [nTPM]":"0.8","Tissue RNA - hypothalamus [nTPM]":"0.8","Tissue RNA - kidney [nTPM]":"6.2","Tissue RNA - liver [nTPM]":"3.6","Tissue RNA - lung [nTPM]":"2.2","Tissue RNA - lymph node [nTPM]":"4.0","Tissue RNA - medulla oblongata [nTPM]":"0.8","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"1.7","Tissue RNA - pancreas [nTPM]":"1.3","Tissue RNA - parathyroid gland [nTPM]":"2.2","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"2.4","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"1.5","Tissue RNA - rectum [nTPM]":"15.1","Tissue RNA - retina [nTPM]":"1.9","Tissue RNA - salivary gland [nTPM]":"1.8","Tissue RNA - seminal vesicle [nTPM]":"1.3","Tissue RNA - skeletal muscle [nTPM]":"5.7","Tissue RNA - skin 1 [nTPM]":"1.4","Tissue RNA - small intestine [nTPM]":"15.3","Tissue RNA - smooth muscle [nTPM]":"2.9","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"1.8","Tissue RNA - stomach 1 [nTPM]":"2.8","Tissue RNA - testis [nTPM]":"2.8","Tissue RNA - thalamus [nTPM]":"0.9","Tissue RNA - thymus [nTPM]":"13.8","Tissue RNA - thyroid gland [nTPM]":"1.2","Tissue RNA - tongue [nTPM]":"9.5","Tissue RNA - tonsil [nTPM]":"4.7","Tissue RNA - urinary bladder [nTPM]":"3.1","Tissue RNA - vagina [nTPM]":"2.2","Tissue RNA - white matter [nTPM]":"1.1","Cell RNA - A-431 [nTPM]":"15.6","Cell RNA - A549 [nTPM]":"11.8","Cell RNA - AF22 [nTPM]":"8.9","Cell RNA - AN3-CA [nTPM]":"16.3","Cell RNA - ASC diff [nTPM]":"2.9","Cell RNA - ASC TERT1 [nTPM]":"5.4","Cell RNA - BEWO [nTPM]":"12.2","Cell RNA - BJ [nTPM]":"14.0","Cell RNA - BJ hTERT+ [nTPM]":"3.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.7","Cell RNA - CACO-2 [nTPM]":"18.3","Cell RNA - CAPAN-2 [nTPM]":"8.4","Cell RNA - Daudi [nTPM]":"35.0","Cell RNA - EFO-21 [nTPM]":"7.2","Cell RNA - fHDF\/TERT166 [nTPM]":"7.0","Cell RNA - GAMG [nTPM]":"7.6","Cell RNA - HaCaT [nTPM]":"19.2","Cell RNA - HAP1 [nTPM]":"28.6","Cell RNA - HBEC3-KT [nTPM]":"21.8","Cell RNA - HBF TERT88 [nTPM]":"16.7","Cell RNA - HDLM-2 [nTPM]":"14.7","Cell RNA - HEK 293 [nTPM]":"23.6","Cell RNA - HEL [nTPM]":"30.4","Cell RNA - HeLa [nTPM]":"9.9","Cell RNA - Hep G2 [nTPM]":"13.6","Cell RNA - HHSteC [nTPM]":"4.3","Cell RNA - HL-60 [nTPM]":"20.3","Cell RNA - HMC-1 [nTPM]":"11.6","Cell RNA - HSkMC [nTPM]":"6.8","Cell RNA - hTCEpi [nTPM]":"9.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.0","Cell RNA - hTERT-HME1 [nTPM]":"5.0","Cell RNA - hTERT-RPE1 [nTPM]":"3.5","Cell RNA - HUVEC TERT2 [nTPM]":"10.7","Cell RNA - JURKAT [nTPM]":"22.8","Cell RNA - K-562 [nTPM]":"28.4","Cell RNA - Karpas-707 [nTPM]":"9.3","Cell RNA - LHCN-M2 [nTPM]":"14.4","Cell RNA - MCF7 [nTPM]":"24.9","Cell RNA - MOLT-4 [nTPM]":"64.6","Cell RNA - NB-4 [nTPM]":"14.7","Cell RNA - NTERA-2 [nTPM]":"17.9","Cell RNA - OE19 [nTPM]":"24.9","Cell RNA - PC-3 [nTPM]":"11.3","Cell RNA - REH [nTPM]":"29.6","Cell RNA - RH-30 [nTPM]":"25.1","Cell RNA - RPMI-8226 [nTPM]":"25.5","Cell RNA - RPTEC TERT1 [nTPM]":"12.0","Cell RNA - RT4 [nTPM]":"7.3","Cell RNA - SCLC-21H [nTPM]":"25.7","Cell RNA - SH-SY5Y [nTPM]":"15.8","Cell RNA - SiHa [nTPM]":"13.5","Cell RNA - SK-BR-3 [nTPM]":"27.6","Cell RNA - SK-MEL-30 [nTPM]":"15.9","Cell RNA - SuSa [nTPM]":"9.2","Cell RNA - T-47d [nTPM]":"9.9","Cell RNA - THP-1 [nTPM]":"23.7","Cell RNA - TIME [nTPM]":"6.8","Cell RNA - U-138 MG [nTPM]":"11.1","Cell RNA - U-2 OS [nTPM]":"17.9","Cell RNA - U-2197 [nTPM]":"22.9","Cell RNA - U-251 MG [nTPM]":"22.5","Cell RNA - U-266\/70 [nTPM]":"3.6","Cell RNA - U-266\/84 [nTPM]":"14.1","Cell RNA - U-698 [nTPM]":"25.6","Cell RNA - U-87 MG [nTPM]":"10.9","Cell RNA - U-937 [nTPM]":"51.3","Cell RNA - WM-115 [nTPM]":"8.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.8","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"2.3","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"2.6","Blood RNA - naive B-cell [nTPM]":"2.4","Blood RNA - naive CD4 T-cell [nTPM]":"1.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"1.2","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"0.8","Brain RNA - basal ganglia [nTPM]":"0.9","Brain RNA - cerebellum [nTPM]":"2.6","Brain RNA - cerebral cortex [nTPM]":"1.4","Brain RNA - hippocampal formation [nTPM]":"0.8","Brain RNA - hypothalamus [nTPM]":"0.8","Brain RNA - medulla oblongata [nTPM]":"0.8","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"0.9","Brain RNA - white matter [nTPM]":"1.1","Single Cell Type RNA - Adipocytes [nTPM]":"3.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"18.9","Single Cell Type RNA - B-cells [nTPM]":"4.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"2.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"3.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.7","Single Cell Type RNA - dendritic cells [nTPM]":"4.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.1","Single Cell Type RNA - Early spermatids [nTPM]":"12.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.8","Single Cell Type RNA - Endothelial cells [nTPM]":"2.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.8","Single Cell Type RNA - Erythroid cells [nTPM]":"8.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.4","Single Cell Type RNA - Fibroblasts [nTPM]":"3.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"4.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.8","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"32.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"5.3","Single Cell Type RNA - Langerhans cells [nTPM]":"2.7","Single Cell Type RNA - Late spermatids [nTPM]":"4.1","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"7.7","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"6.2","Single Cell Type RNA - Muller glia cells [nTPM]":"1.2","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.6","Single Cell Type RNA - Paneth cells [nTPM]":"9.8","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"9.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"29.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"26.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.5","Single Cell Type RNA - Spermatocytes [nTPM]":"12.5","Single Cell Type RNA - Spermatogonia [nTPM]":"9.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.3","Single Cell Type RNA - T-cells [nTPM]":"4.8","Single Cell Type RNA - Theca cells [nTPM]":"4.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"29.8","Single Cell Type RNA - Urothelial cells [nTPM]":"3.3"},{"Gene":"PDSS2","Gene synonym":["bA59I9.3","C6orf210","COQ1B"],"Ensembl":"ENSG00000164494","Gene description":"Decaprenyl diphosphate synthase subunit 2","Uniprot":["Q86YH6"],"Chromosome":"6","Position":"107152562-107459564","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Isoprene biosynthesis","Ubiquinone biosynthesis"],"Molecular function":["Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Microglial cells":"82.4","Oligodendrocyte precursor cells":"72.9","Oligodendrocytes":"74.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029685","HPA029686"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA029685":"AB_10600219","HPA029686":"AB_10602309"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.34e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.74e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.75e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.9","Tissue RNA - adrenal gland [nTPM]":"17.9","Tissue RNA - amygdala [nTPM]":"4.6","Tissue RNA - appendix [nTPM]":"6.3","Tissue RNA - basal ganglia [nTPM]":"5.2","Tissue RNA - bone marrow [nTPM]":"9.0","Tissue RNA - breast [nTPM]":"8.1","Tissue RNA - cerebellum [nTPM]":"6.1","Tissue RNA - cerebral cortex [nTPM]":"5.7","Tissue RNA - cervix [nTPM]":"9.2","Tissue RNA - choroid plexus [nTPM]":"6.8","Tissue RNA - colon [nTPM]":"12.4","Tissue RNA - duodenum [nTPM]":"9.3","Tissue RNA - endometrium 1 [nTPM]":"6.8","Tissue RNA - epididymis [nTPM]":"6.5","Tissue RNA - esophagus [nTPM]":"8.6","Tissue RNA - fallopian tube [nTPM]":"8.6","Tissue RNA - gallbladder [nTPM]":"8.7","Tissue RNA - heart muscle [nTPM]":"13.9","Tissue RNA - hippocampal formation [nTPM]":"4.6","Tissue RNA - hypothalamus [nTPM]":"5.2","Tissue RNA - kidney [nTPM]":"21.6","Tissue RNA - liver [nTPM]":"27.1","Tissue RNA - lung [nTPM]":"8.0","Tissue RNA - lymph node [nTPM]":"7.6","Tissue RNA - medulla oblongata [nTPM]":"4.9","Tissue RNA - midbrain [nTPM]":"4.7","Tissue RNA - ovary [nTPM]":"9.1","Tissue RNA - pancreas [nTPM]":"8.4","Tissue RNA - parathyroid gland [nTPM]":"13.2","Tissue RNA - pituitary gland [nTPM]":"8.5","Tissue RNA - placenta [nTPM]":"6.8","Tissue RNA - pons [nTPM]":"5.0","Tissue RNA - prostate [nTPM]":"14.6","Tissue RNA - rectum [nTPM]":"13.2","Tissue RNA - retina [nTPM]":"6.0","Tissue RNA - salivary gland [nTPM]":"15.3","Tissue RNA - seminal vesicle [nTPM]":"7.4","Tissue RNA - skeletal muscle [nTPM]":"12.5","Tissue RNA - skin 1 [nTPM]":"6.3","Tissue RNA - small intestine [nTPM]":"9.6","Tissue RNA - smooth muscle [nTPM]":"8.5","Tissue RNA - spinal cord [nTPM]":"4.7","Tissue RNA - spleen [nTPM]":"6.7","Tissue RNA - stomach 1 [nTPM]":"9.6","Tissue RNA - testis [nTPM]":"7.7","Tissue RNA - thalamus [nTPM]":"5.3","Tissue RNA - thymus [nTPM]":"8.1","Tissue RNA - thyroid gland [nTPM]":"13.3","Tissue RNA - tongue [nTPM]":"13.7","Tissue RNA - tonsil [nTPM]":"7.1","Tissue RNA - urinary bladder [nTPM]":"7.6","Tissue RNA - vagina [nTPM]":"6.1","Tissue RNA - white matter [nTPM]":"6.1","Cell RNA - A-431 [nTPM]":"7.6","Cell RNA - A549 [nTPM]":"10.0","Cell RNA - AF22 [nTPM]":"8.3","Cell RNA - AN3-CA [nTPM]":"13.2","Cell RNA - ASC diff [nTPM]":"14.2","Cell RNA - ASC TERT1 [nTPM]":"18.0","Cell RNA - BEWO [nTPM]":"19.2","Cell RNA - BJ [nTPM]":"13.1","Cell RNA - BJ hTERT+ [nTPM]":"16.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.8","Cell RNA - CACO-2 [nTPM]":"10.0","Cell RNA - CAPAN-2 [nTPM]":"10.8","Cell RNA - Daudi [nTPM]":"14.4","Cell RNA - EFO-21 [nTPM]":"11.7","Cell RNA - fHDF\/TERT166 [nTPM]":"14.7","Cell RNA - GAMG [nTPM]":"13.1","Cell RNA - HaCaT [nTPM]":"10.2","Cell RNA - HAP1 [nTPM]":"20.3","Cell RNA - HBEC3-KT [nTPM]":"16.5","Cell RNA - HBF TERT88 [nTPM]":"16.7","Cell RNA - HDLM-2 [nTPM]":"9.1","Cell RNA - HEK 293 [nTPM]":"9.8","Cell RNA - HEL [nTPM]":"14.4","Cell RNA - HeLa [nTPM]":"11.4","Cell RNA - Hep G2 [nTPM]":"16.9","Cell RNA - HHSteC [nTPM]":"15.0","Cell RNA - HL-60 [nTPM]":"18.5","Cell RNA - HMC-1 [nTPM]":"11.1","Cell RNA - HSkMC [nTPM]":"13.5","Cell RNA - hTCEpi [nTPM]":"19.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.5","Cell RNA - hTERT-HME1 [nTPM]":"15.3","Cell RNA - hTERT-RPE1 [nTPM]":"10.8","Cell RNA - HUVEC TERT2 [nTPM]":"13.1","Cell RNA - JURKAT [nTPM]":"16.5","Cell RNA - K-562 [nTPM]":"20.7","Cell RNA - Karpas-707 [nTPM]":"19.0","Cell RNA - LHCN-M2 [nTPM]":"12.2","Cell RNA - MCF7 [nTPM]":"9.3","Cell RNA - MOLT-4 [nTPM]":"5.4","Cell RNA - NB-4 [nTPM]":"19.7","Cell RNA - NTERA-2 [nTPM]":"5.3","Cell RNA - OE19 [nTPM]":"17.3","Cell RNA - PC-3 [nTPM]":"12.7","Cell RNA - REH [nTPM]":"9.7","Cell RNA - RH-30 [nTPM]":"7.4","Cell RNA - RPMI-8226 [nTPM]":"11.7","Cell RNA - RPTEC TERT1 [nTPM]":"15.2","Cell RNA - RT4 [nTPM]":"10.2","Cell RNA - SCLC-21H [nTPM]":"8.2","Cell RNA - SH-SY5Y [nTPM]":"7.1","Cell RNA - SiHa [nTPM]":"9.0","Cell RNA - SK-BR-3 [nTPM]":"15.4","Cell RNA - SK-MEL-30 [nTPM]":"19.7","Cell RNA - SuSa [nTPM]":"9.0","Cell RNA - T-47d [nTPM]":"12.7","Cell RNA - THP-1 [nTPM]":"22.3","Cell RNA - TIME [nTPM]":"8.3","Cell RNA - U-138 MG [nTPM]":"8.8","Cell RNA - U-2 OS [nTPM]":"5.2","Cell RNA - U-2197 [nTPM]":"12.4","Cell RNA - U-251 MG [nTPM]":"11.4","Cell RNA - U-266\/70 [nTPM]":"5.3","Cell RNA - U-266\/84 [nTPM]":"6.8","Cell RNA - U-698 [nTPM]":"11.3","Cell RNA - U-87 MG [nTPM]":"16.3","Cell RNA - U-937 [nTPM]":"27.4","Cell RNA - WM-115 [nTPM]":"16.3","Blood RNA - basophil [nTPM]":"3.2","Blood RNA - classical monocyte [nTPM]":"5.1","Blood RNA - eosinophil [nTPM]":"2.8","Blood RNA - gdT-cell [nTPM]":"3.7","Blood RNA - intermediate monocyte [nTPM]":"5.9","Blood RNA - MAIT T-cell [nTPM]":"5.9","Blood RNA - memory B-cell [nTPM]":"4.7","Blood RNA - memory CD4 T-cell [nTPM]":"3.8","Blood RNA - memory CD8 T-cell [nTPM]":"4.7","Blood RNA - myeloid DC [nTPM]":"7.0","Blood RNA - naive B-cell [nTPM]":"5.5","Blood RNA - naive CD4 T-cell [nTPM]":"5.0","Blood RNA - naive CD8 T-cell [nTPM]":"4.8","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"3.6","Blood RNA - non-classical monocyte [nTPM]":"9.9","Blood RNA - plasmacytoid DC [nTPM]":"3.3","Blood RNA - T-reg [nTPM]":"5.5","Blood RNA - total PBMC [nTPM]":"3.4","Brain RNA - amygdala [nTPM]":"4.6","Brain RNA - basal ganglia [nTPM]":"5.2","Brain RNA - cerebellum [nTPM]":"6.1","Brain RNA - cerebral cortex [nTPM]":"5.7","Brain RNA - hippocampal formation [nTPM]":"4.6","Brain RNA - hypothalamus [nTPM]":"5.2","Brain RNA - medulla oblongata [nTPM]":"4.9","Brain RNA - midbrain [nTPM]":"4.7","Brain RNA - pons [nTPM]":"5.0","Brain RNA - spinal cord [nTPM]":"4.7","Brain RNA - thalamus [nTPM]":"5.3","Brain RNA - white matter [nTPM]":"6.1","Single Cell Type RNA - Adipocytes [nTPM]":"11.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.1","Single Cell Type RNA - Astrocytes [nTPM]":"64.9","Single Cell Type RNA - B-cells [nTPM]":"12.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"8.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"13.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"26.9","Single Cell Type RNA - dendritic cells [nTPM]":"8.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"12.7","Single Cell Type RNA - Early spermatids [nTPM]":"37.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.3","Single Cell Type RNA - Endothelial cells [nTPM]":"8.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.3","Single Cell Type RNA - Erythroid cells [nTPM]":"8.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"53.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.3","Single Cell Type RNA - Fibroblasts [nTPM]":"9.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.9","Single Cell Type RNA - granulocytes [nTPM]":"14.0","Single Cell Type RNA - Granulosa cells [nTPM]":"11.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"32.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.8","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"67.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.3","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"9.8","Single Cell Type RNA - Langerhans cells [nTPM]":"5.1","Single Cell Type RNA - Late spermatids [nTPM]":"12.7","Single Cell Type RNA - Leydig cells [nTPM]":"5.3","Single Cell Type RNA - Macrophages [nTPM]":"10.2","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"82.4","Single Cell Type RNA - monocytes [nTPM]":"8.5","Single Cell Type RNA - Muller glia cells [nTPM]":"11.8","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"72.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"74.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.7","Single Cell Type RNA - Paneth cells [nTPM]":"14.4","Single Cell Type RNA - Peritubular cells [nTPM]":"9.4","Single Cell Type RNA - Plasma cells [nTPM]":"13.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"40.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.5","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.9","Single Cell Type RNA - Spermatocytes [nTPM]":"21.7","Single Cell Type RNA - Spermatogonia [nTPM]":"11.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.9","Single Cell Type RNA - T-cells [nTPM]":"9.8","Single Cell Type RNA - Theca cells [nTPM]":"13.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.0","Single Cell Type RNA - Urothelial cells [nTPM]":"12.5"},{"Gene":"PDYN","Gene synonym":["ADCA","PENKB","SCA23"],"Ensembl":"ENSG00000101327","Gene description":"Prodynorphin","Uniprot":["P01213"],"Chromosome":"20","Position":"1978757-1994285","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins","Transporters"],"Biological process":null,"Molecular function":["Endorphin","Neuropeptide","Neurotransmitter","Opioid peptide"],"Disease involvement":["Disease variant","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"47.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"83","RNA single cell type specific nTPM":{"Early spermatids":"47.8","Late spermatids":"119.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"29","RNA cancer specific FPKM":{"glioma":"2.6","ovarian cancer":"1.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"THP-1":"1.0"},"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"basal ganglia":"152.2","hypothalamus":"60.7"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"basal ganglia":"132.2"},"Antibody":["HPA053342","CAB079777"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in brain","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB079777":null,"HPA053342":"AB_2682121"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"43.2","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"31.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"43.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"47.0","Tissue RNA - hypothalamus [nTPM]":"17.6","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"1.8","Tissue RNA - midbrain [nTPM]":"4.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"21.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"8.3","Tissue RNA - thalamus [nTPM]":"9.2","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"4.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"1.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"43.2","Brain RNA - basal ganglia [nTPM]":"31.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"43.1","Brain RNA - hippocampal formation [nTPM]":"47.0","Brain RNA - hypothalamus [nTPM]":"17.6","Brain RNA - medulla oblongata [nTPM]":"1.8","Brain RNA - midbrain [nTPM]":"4.1","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"21.0","Brain RNA - thalamus [nTPM]":"9.2","Brain RNA - white matter [nTPM]":"4.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"47.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"119.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PEPD","Gene synonym":[],"Ensembl":"ENSG00000124299","Gene description":"Peptidase D","Uniprot":["P12955"],"Chromosome":"19","Position":"33386950-33521791","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Collagen degradation"],"Molecular function":["Dipeptidase","Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"209.5","kidney":"277.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Proximal enterocytes":"833.0","Proximal tubular cells":"1278.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015599","HPA072045"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"860000000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA015599":"AB_1855192","HPA072045":"AB_2732194"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.50e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Tissue RNA - adipose tissue [nTPM]":"53.2","Tissue RNA - adrenal gland [nTPM]":"56.0","Tissue RNA - amygdala [nTPM]":"28.5","Tissue RNA - appendix [nTPM]":"26.9","Tissue RNA - basal ganglia [nTPM]":"35.5","Tissue RNA - bone marrow [nTPM]":"14.3","Tissue RNA - breast [nTPM]":"43.6","Tissue RNA - cerebellum [nTPM]":"35.6","Tissue RNA - cerebral cortex [nTPM]":"30.5","Tissue RNA - cervix [nTPM]":"36.9","Tissue RNA - choroid plexus [nTPM]":"33.5","Tissue RNA - colon [nTPM]":"44.2","Tissue RNA - duodenum [nTPM]":"180.5","Tissue RNA - endometrium 1 [nTPM]":"49.7","Tissue RNA - epididymis [nTPM]":"9.9","Tissue RNA - esophagus [nTPM]":"42.8","Tissue RNA - fallopian tube [nTPM]":"34.2","Tissue RNA - gallbladder [nTPM]":"31.2","Tissue RNA - heart muscle [nTPM]":"24.3","Tissue RNA - hippocampal formation [nTPM]":"28.7","Tissue RNA - hypothalamus [nTPM]":"30.9","Tissue RNA - kidney [nTPM]":"277.7","Tissue RNA - liver [nTPM]":"117.8","Tissue RNA - lung [nTPM]":"38.1","Tissue RNA - lymph node [nTPM]":"30.7","Tissue RNA - medulla oblongata [nTPM]":"36.2","Tissue RNA - midbrain [nTPM]":"30.8","Tissue RNA - ovary [nTPM]":"35.9","Tissue RNA - pancreas [nTPM]":"27.1","Tissue RNA - parathyroid gland [nTPM]":"29.3","Tissue RNA - pituitary gland [nTPM]":"42.5","Tissue RNA - placenta [nTPM]":"21.9","Tissue RNA - pons [nTPM]":"36.3","Tissue RNA - prostate [nTPM]":"23.6","Tissue RNA - rectum [nTPM]":"14.8","Tissue RNA - retina [nTPM]":"11.8","Tissue RNA - salivary gland [nTPM]":"33.6","Tissue RNA - seminal vesicle [nTPM]":"22.9","Tissue RNA - skeletal muscle [nTPM]":"35.6","Tissue RNA - skin 1 [nTPM]":"43.1","Tissue RNA - small intestine [nTPM]":"209.5","Tissue RNA - smooth muscle [nTPM]":"24.5","Tissue RNA - spinal cord [nTPM]":"34.6","Tissue RNA - spleen [nTPM]":"38.2","Tissue RNA - stomach 1 [nTPM]":"33.6","Tissue RNA - testis [nTPM]":"18.3","Tissue RNA - thalamus [nTPM]":"33.4","Tissue RNA - thymus [nTPM]":"20.8","Tissue RNA - thyroid gland [nTPM]":"37.0","Tissue RNA - tongue [nTPM]":"23.2","Tissue RNA - tonsil [nTPM]":"21.3","Tissue RNA - urinary bladder [nTPM]":"40.1","Tissue RNA - vagina [nTPM]":"28.2","Tissue RNA - white matter [nTPM]":"43.4","Cell RNA - A-431 [nTPM]":"43.2","Cell RNA - A549 [nTPM]":"118.7","Cell RNA - AF22 [nTPM]":"26.4","Cell RNA - AN3-CA [nTPM]":"53.1","Cell RNA - ASC diff [nTPM]":"114.9","Cell RNA - ASC TERT1 [nTPM]":"44.9","Cell RNA - BEWO [nTPM]":"80.6","Cell RNA - BJ [nTPM]":"37.4","Cell RNA - BJ hTERT+ [nTPM]":"65.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"45.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"52.7","Cell RNA - CACO-2 [nTPM]":"104.7","Cell RNA - CAPAN-2 [nTPM]":"34.2","Cell RNA - Daudi [nTPM]":"18.8","Cell RNA - EFO-21 [nTPM]":"53.5","Cell RNA - fHDF\/TERT166 [nTPM]":"73.2","Cell RNA - GAMG [nTPM]":"33.9","Cell RNA - HaCaT [nTPM]":"11.2","Cell RNA - HAP1 [nTPM]":"39.5","Cell RNA - HBEC3-KT [nTPM]":"28.5","Cell RNA - HBF TERT88 [nTPM]":"23.4","Cell RNA - HDLM-2 [nTPM]":"51.3","Cell RNA - HEK 293 [nTPM]":"50.4","Cell RNA - HEL [nTPM]":"107.7","Cell RNA - HeLa [nTPM]":"24.6","Cell RNA - Hep G2 [nTPM]":"108.3","Cell RNA - HHSteC [nTPM]":"91.6","Cell RNA - HL-60 [nTPM]":"29.6","Cell RNA - HMC-1 [nTPM]":"128.8","Cell RNA - HSkMC [nTPM]":"63.6","Cell RNA - hTCEpi [nTPM]":"29.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"38.2","Cell RNA - hTERT-HME1 [nTPM]":"18.3","Cell RNA - hTERT-RPE1 [nTPM]":"27.8","Cell RNA - HUVEC TERT2 [nTPM]":"56.4","Cell RNA - JURKAT [nTPM]":"34.4","Cell RNA - K-562 [nTPM]":"22.7","Cell RNA - Karpas-707 [nTPM]":"49.4","Cell RNA - LHCN-M2 [nTPM]":"44.2","Cell RNA - MCF7 [nTPM]":"54.3","Cell RNA - MOLT-4 [nTPM]":"19.0","Cell RNA - NB-4 [nTPM]":"11.7","Cell RNA - NTERA-2 [nTPM]":"46.2","Cell RNA - OE19 [nTPM]":"79.6","Cell RNA - PC-3 [nTPM]":"48.8","Cell RNA - REH [nTPM]":"45.3","Cell RNA - RH-30 [nTPM]":"41.0","Cell RNA - RPMI-8226 [nTPM]":"51.2","Cell RNA - RPTEC TERT1 [nTPM]":"39.4","Cell RNA - RT4 [nTPM]":"108.8","Cell RNA - SCLC-21H [nTPM]":"40.3","Cell RNA - SH-SY5Y [nTPM]":"106.4","Cell RNA - SiHa [nTPM]":"64.2","Cell RNA - SK-BR-3 [nTPM]":"31.3","Cell RNA - SK-MEL-30 [nTPM]":"62.5","Cell RNA - SuSa [nTPM]":"18.2","Cell RNA - T-47d [nTPM]":"25.1","Cell RNA - THP-1 [nTPM]":"36.3","Cell RNA - TIME [nTPM]":"56.6","Cell RNA - U-138 MG [nTPM]":"48.3","Cell RNA - U-2 OS [nTPM]":"46.6","Cell RNA - U-2197 [nTPM]":"62.3","Cell RNA - U-251 MG [nTPM]":"41.8","Cell RNA - U-266\/70 [nTPM]":"45.2","Cell RNA - U-266\/84 [nTPM]":"59.1","Cell RNA - U-698 [nTPM]":"13.1","Cell RNA - U-87 MG [nTPM]":"49.5","Cell RNA - U-937 [nTPM]":"48.2","Cell RNA - WM-115 [nTPM]":"65.8","Blood RNA - basophil [nTPM]":"113.7","Blood RNA - classical monocyte [nTPM]":"117.2","Blood RNA - eosinophil [nTPM]":"8.3","Blood RNA - gdT-cell [nTPM]":"75.5","Blood RNA - intermediate monocyte [nTPM]":"123.6","Blood RNA - MAIT T-cell [nTPM]":"65.5","Blood RNA - memory B-cell [nTPM]":"49.6","Blood RNA - memory CD4 T-cell [nTPM]":"74.0","Blood RNA - memory CD8 T-cell [nTPM]":"69.8","Blood RNA - myeloid DC [nTPM]":"100.6","Blood RNA - naive B-cell [nTPM]":"50.5","Blood RNA - naive CD4 T-cell [nTPM]":"47.1","Blood RNA - naive CD8 T-cell [nTPM]":"55.6","Blood RNA - neutrophil [nTPM]":"6.1","Blood RNA - NK-cell [nTPM]":"55.6","Blood RNA - non-classical monocyte [nTPM]":"92.5","Blood RNA - plasmacytoid DC [nTPM]":"31.0","Blood RNA - T-reg [nTPM]":"76.1","Blood RNA - total PBMC [nTPM]":"119.6","Brain RNA - amygdala [nTPM]":"28.5","Brain RNA - basal ganglia [nTPM]":"35.5","Brain RNA - cerebellum [nTPM]":"35.6","Brain RNA - cerebral cortex [nTPM]":"30.5","Brain RNA - hippocampal formation [nTPM]":"28.7","Brain RNA - hypothalamus [nTPM]":"30.9","Brain RNA - medulla oblongata [nTPM]":"36.2","Brain RNA - midbrain [nTPM]":"30.8","Brain RNA - pons [nTPM]":"36.3","Brain RNA - spinal cord [nTPM]":"34.6","Brain RNA - thalamus [nTPM]":"33.4","Brain RNA - white matter [nTPM]":"43.4","Single Cell Type RNA - Adipocytes [nTPM]":"56.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.4","Single Cell Type RNA - Astrocytes [nTPM]":"11.4","Single Cell Type RNA - B-cells [nTPM]":"29.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"19.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"36.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"33.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"52.9","Single Cell Type RNA - Club cells [nTPM]":"23.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"73.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"21.4","Single Cell Type RNA - dendritic cells [nTPM]":"32.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"197.6","Single Cell Type RNA - Ductal cells [nTPM]":"77.2","Single Cell Type RNA - Early spermatids [nTPM]":"8.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.1","Single Cell Type RNA - Endothelial cells [nTPM]":"50.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.3","Single Cell Type RNA - Erythroid cells [nTPM]":"25.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"44.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"67.3","Single Cell Type RNA - Fibroblasts [nTPM]":"38.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.0","Single Cell Type RNA - granulocytes [nTPM]":"57.6","Single Cell Type RNA - Granulosa cells [nTPM]":"41.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"52.8","Single Cell Type RNA - Hepatocytes [nTPM]":"180.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"227.2","Single Cell Type RNA - Horizontal cells [nTPM]":"62.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"35.6","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"59.7","Single Cell Type RNA - Langerhans cells [nTPM]":"40.9","Single Cell Type RNA - Late spermatids [nTPM]":"13.2","Single Cell Type RNA - Leydig cells [nTPM]":"49.4","Single Cell Type RNA - Macrophages [nTPM]":"75.3","Single Cell Type RNA - Melanocytes [nTPM]":"67.6","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"102.2","Single Cell Type RNA - Muller glia cells [nTPM]":"73.6","Single Cell Type RNA - NK-cells [nTPM]":"34.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"24.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"33.8","Single Cell Type RNA - Paneth cells [nTPM]":"79.3","Single Cell Type RNA - Peritubular cells [nTPM]":"60.5","Single Cell Type RNA - Plasma cells [nTPM]":"31.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"22.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"833.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1278.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"27.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"33.7","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"37.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"43.1","Single Cell Type RNA - Spermatocytes [nTPM]":"10.2","Single Cell Type RNA - Spermatogonia [nTPM]":"44.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"34.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"30.4","Single Cell Type RNA - T-cells [nTPM]":"33.7","Single Cell Type RNA - Theca cells [nTPM]":"48.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"44.6","Single Cell Type RNA - Urothelial cells [nTPM]":"22.2"},{"Gene":"PEX1","Gene synonym":["ZWS","ZWS1"],"Ensembl":"ENSG00000127980","Gene description":"Peroxisomal biogenesis factor 1","Uniprot":["O43933"],"Chromosome":"7","Position":"92487020-92528520","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Peroxisome biogenesis","Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Amelogenesis imperfecta","Deafness","Disease variant","Peroxisome biogenesis disorder","Zellweger syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020235"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Peroxisomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Peroxisomes"],"Subcellular additional location":null,"Antibody RRID":{"HPA020235":"AB_1855224"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.8","Tissue RNA - adrenal gland [nTPM]":"6.9","Tissue RNA - amygdala [nTPM]":"2.6","Tissue RNA - appendix [nTPM]":"6.0","Tissue RNA - basal ganglia [nTPM]":"4.7","Tissue RNA - bone marrow [nTPM]":"4.1","Tissue RNA - breast [nTPM]":"8.7","Tissue RNA - cerebellum [nTPM]":"4.6","Tissue RNA - cerebral cortex [nTPM]":"4.3","Tissue RNA - cervix [nTPM]":"6.4","Tissue RNA - choroid plexus [nTPM]":"2.5","Tissue RNA - colon [nTPM]":"8.6","Tissue RNA - duodenum [nTPM]":"6.6","Tissue RNA - endometrium 1 [nTPM]":"6.7","Tissue RNA - epididymis [nTPM]":"11.2","Tissue RNA - esophagus [nTPM]":"6.1","Tissue RNA - fallopian tube [nTPM]":"5.6","Tissue RNA - gallbladder [nTPM]":"4.7","Tissue RNA - heart muscle [nTPM]":"8.9","Tissue RNA - hippocampal formation [nTPM]":"2.4","Tissue RNA - hypothalamus [nTPM]":"3.1","Tissue RNA - kidney [nTPM]":"14.2","Tissue RNA - liver [nTPM]":"13.0","Tissue RNA - lung [nTPM]":"5.3","Tissue RNA - lymph node [nTPM]":"6.9","Tissue RNA - medulla oblongata [nTPM]":"3.5","Tissue RNA - midbrain [nTPM]":"3.5","Tissue RNA - ovary [nTPM]":"6.8","Tissue RNA - pancreas [nTPM]":"8.8","Tissue RNA - parathyroid gland [nTPM]":"11.7","Tissue RNA - pituitary gland [nTPM]":"6.3","Tissue RNA - placenta [nTPM]":"4.2","Tissue RNA - pons [nTPM]":"4.1","Tissue RNA - prostate [nTPM]":"7.8","Tissue RNA - rectum [nTPM]":"9.5","Tissue RNA - retina [nTPM]":"13.2","Tissue RNA - salivary gland [nTPM]":"9.1","Tissue RNA - seminal vesicle [nTPM]":"7.0","Tissue RNA - skeletal muscle [nTPM]":"9.1","Tissue RNA - skin 1 [nTPM]":"7.9","Tissue RNA - small intestine [nTPM]":"8.1","Tissue RNA - smooth muscle [nTPM]":"5.4","Tissue RNA - spinal cord [nTPM]":"2.8","Tissue RNA - spleen [nTPM]":"6.0","Tissue RNA - stomach 1 [nTPM]":"8.2","Tissue RNA - testis [nTPM]":"6.7","Tissue RNA - thalamus [nTPM]":"3.0","Tissue RNA - thymus [nTPM]":"7.9","Tissue RNA - thyroid gland [nTPM]":"8.6","Tissue RNA - tongue [nTPM]":"9.9","Tissue RNA - tonsil [nTPM]":"6.7","Tissue RNA - urinary bladder [nTPM]":"5.6","Tissue RNA - vagina [nTPM]":"5.8","Tissue RNA - white matter [nTPM]":"6.3","Cell RNA - A-431 [nTPM]":"8.3","Cell RNA - A549 [nTPM]":"8.9","Cell RNA - AF22 [nTPM]":"14.4","Cell RNA - AN3-CA [nTPM]":"24.6","Cell RNA - ASC diff [nTPM]":"8.9","Cell RNA - ASC TERT1 [nTPM]":"7.6","Cell RNA - BEWO [nTPM]":"13.0","Cell RNA - BJ [nTPM]":"5.4","Cell RNA - BJ hTERT+ [nTPM]":"7.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.1","Cell RNA - CACO-2 [nTPM]":"5.5","Cell RNA - CAPAN-2 [nTPM]":"8.7","Cell RNA - Daudi [nTPM]":"12.2","Cell RNA - EFO-21 [nTPM]":"12.0","Cell RNA - fHDF\/TERT166 [nTPM]":"6.3","Cell RNA - GAMG [nTPM]":"9.6","Cell RNA - HaCaT [nTPM]":"8.4","Cell RNA - HAP1 [nTPM]":"11.0","Cell RNA - HBEC3-KT [nTPM]":"9.9","Cell RNA - HBF TERT88 [nTPM]":"10.0","Cell RNA - HDLM-2 [nTPM]":"12.7","Cell RNA - HEK 293 [nTPM]":"9.7","Cell RNA - HEL [nTPM]":"5.8","Cell RNA - HeLa [nTPM]":"9.5","Cell RNA - Hep G2 [nTPM]":"7.0","Cell RNA - HHSteC [nTPM]":"6.2","Cell RNA - HL-60 [nTPM]":"10.6","Cell RNA - HMC-1 [nTPM]":"6.4","Cell RNA - HSkMC [nTPM]":"8.2","Cell RNA - hTCEpi [nTPM]":"8.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.4","Cell RNA - hTERT-HME1 [nTPM]":"12.7","Cell RNA - hTERT-RPE1 [nTPM]":"8.0","Cell RNA - HUVEC TERT2 [nTPM]":"9.9","Cell RNA - JURKAT [nTPM]":"12.6","Cell RNA - K-562 [nTPM]":"21.9","Cell RNA - Karpas-707 [nTPM]":"17.2","Cell RNA - LHCN-M2 [nTPM]":"10.1","Cell RNA - MCF7 [nTPM]":"15.5","Cell RNA - MOLT-4 [nTPM]":"21.3","Cell RNA - NB-4 [nTPM]":"10.4","Cell RNA - NTERA-2 [nTPM]":"10.0","Cell RNA - OE19 [nTPM]":"12.3","Cell RNA - PC-3 [nTPM]":"8.3","Cell RNA - REH [nTPM]":"15.0","Cell RNA - RH-30 [nTPM]":"16.0","Cell RNA - RPMI-8226 [nTPM]":"15.3","Cell RNA - RPTEC TERT1 [nTPM]":"8.8","Cell RNA - RT4 [nTPM]":"12.0","Cell RNA - SCLC-21H [nTPM]":"10.6","Cell RNA - SH-SY5Y [nTPM]":"17.1","Cell RNA - SiHa [nTPM]":"12.4","Cell RNA - SK-BR-3 [nTPM]":"34.3","Cell RNA - SK-MEL-30 [nTPM]":"10.8","Cell RNA - SuSa [nTPM]":"20.2","Cell RNA - T-47d [nTPM]":"7.1","Cell RNA - THP-1 [nTPM]":"4.4","Cell RNA - TIME [nTPM]":"8.1","Cell RNA - U-138 MG [nTPM]":"6.0","Cell RNA - U-2 OS [nTPM]":"8.1","Cell RNA - U-2197 [nTPM]":"23.0","Cell RNA - U-251 MG [nTPM]":"5.7","Cell RNA - U-266\/70 [nTPM]":"18.9","Cell RNA - U-266\/84 [nTPM]":"15.9","Cell RNA - U-698 [nTPM]":"16.7","Cell RNA - U-87 MG [nTPM]":"5.7","Cell RNA - U-937 [nTPM]":"6.2","Cell RNA - WM-115 [nTPM]":"9.8","Blood RNA - basophil [nTPM]":"0.8","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"1.8","Blood RNA - gdT-cell [nTPM]":"2.5","Blood RNA - intermediate monocyte [nTPM]":"1.8","Blood RNA - MAIT T-cell [nTPM]":"2.5","Blood RNA - memory B-cell [nTPM]":"3.0","Blood RNA - memory CD4 T-cell [nTPM]":"2.6","Blood RNA - memory CD8 T-cell [nTPM]":"2.8","Blood RNA - myeloid DC [nTPM]":"1.2","Blood RNA - naive B-cell [nTPM]":"2.8","Blood RNA - naive CD4 T-cell [nTPM]":"2.9","Blood RNA - naive CD8 T-cell [nTPM]":"3.3","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"4.7","Blood RNA - non-classical monocyte [nTPM]":"2.2","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"2.8","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"2.6","Brain RNA - basal ganglia [nTPM]":"4.7","Brain RNA - cerebellum [nTPM]":"4.6","Brain RNA - cerebral cortex [nTPM]":"4.3","Brain RNA - hippocampal formation [nTPM]":"2.4","Brain RNA - hypothalamus [nTPM]":"3.1","Brain RNA - medulla oblongata [nTPM]":"3.5","Brain RNA - midbrain [nTPM]":"3.5","Brain RNA - pons [nTPM]":"4.1","Brain RNA - spinal cord [nTPM]":"2.8","Brain RNA - thalamus [nTPM]":"3.0","Brain RNA - white matter [nTPM]":"6.3","Single Cell Type RNA - Adipocytes [nTPM]":"14.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.4","Single Cell Type RNA - Astrocytes [nTPM]":"26.1","Single Cell Type RNA - B-cells [nTPM]":"14.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"43.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"29.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"13.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.0","Single Cell Type RNA - dendritic cells [nTPM]":"13.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"6.6","Single Cell Type RNA - Early spermatids [nTPM]":"7.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.7","Single Cell Type RNA - Endothelial cells [nTPM]":"11.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.9","Single Cell Type RNA - Erythroid cells [nTPM]":"12.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"30.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.9","Single Cell Type RNA - Fibroblasts [nTPM]":"11.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.2","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"20.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.2","Single Cell Type RNA - Hepatocytes [nTPM]":"14.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.4","Single Cell Type RNA - Horizontal cells [nTPM]":"40.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"45.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.0","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"7.6","Single Cell Type RNA - Langerhans cells [nTPM]":"3.1","Single Cell Type RNA - Late spermatids [nTPM]":"4.8","Single Cell Type RNA - Leydig cells [nTPM]":"14.3","Single Cell Type RNA - Macrophages [nTPM]":"8.4","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"12.7","Single Cell Type RNA - Muller glia cells [nTPM]":"14.2","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"23.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"55.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.0","Single Cell Type RNA - Paneth cells [nTPM]":"11.3","Single Cell Type RNA - Peritubular cells [nTPM]":"15.1","Single Cell Type RNA - Plasma cells [nTPM]":"11.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"16.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"32.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"42.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.6","Single Cell Type RNA - Spermatocytes [nTPM]":"36.6","Single Cell Type RNA - Spermatogonia [nTPM]":"14.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.3","Single Cell Type RNA - T-cells [nTPM]":"12.0","Single Cell Type RNA - Theca cells [nTPM]":"11.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.2","Single Cell Type RNA - Urothelial cells [nTPM]":"7.7"},{"Gene":"PEX10","Gene synonym":["RNF69"],"Ensembl":"ENSG00000157911","Gene description":"Peroxisomal biogenesis factor 10","Uniprot":["O60683"],"Chromosome":"1","Position":"2403964-2413797","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Peroxisome biogenesis"],"Molecular function":null,"Disease involvement":["Disease variant","Peroxisome biogenesis disorder","Zellweger syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"194.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"55.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049458","HPA049755"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA049458":"AB_2680775","HPA049755":"AB_2680867"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.50e-6"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.16e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Tissue RNA - adipose tissue [nTPM]":"14.9","Tissue RNA - adrenal gland [nTPM]":"28.9","Tissue RNA - amygdala [nTPM]":"22.2","Tissue RNA - appendix [nTPM]":"2.2","Tissue RNA - basal ganglia [nTPM]":"24.3","Tissue RNA - bone marrow [nTPM]":"3.1","Tissue RNA - breast [nTPM]":"13.9","Tissue RNA - cerebellum [nTPM]":"23.5","Tissue RNA - cerebral cortex [nTPM]":"25.7","Tissue RNA - cervix [nTPM]":"10.8","Tissue RNA - choroid plexus [nTPM]":"19.7","Tissue RNA - colon [nTPM]":"11.3","Tissue RNA - duodenum [nTPM]":"6.7","Tissue RNA - endometrium 1 [nTPM]":"11.4","Tissue RNA - epididymis [nTPM]":"8.5","Tissue RNA - esophagus [nTPM]":"17.2","Tissue RNA - fallopian tube [nTPM]":"10.0","Tissue RNA - gallbladder [nTPM]":"4.2","Tissue RNA - heart muscle [nTPM]":"16.1","Tissue RNA - hippocampal formation [nTPM]":"20.6","Tissue RNA - hypothalamus [nTPM]":"21.6","Tissue RNA - kidney [nTPM]":"18.1","Tissue RNA - liver [nTPM]":"22.0","Tissue RNA - lung [nTPM]":"8.8","Tissue RNA - lymph node [nTPM]":"4.3","Tissue RNA - medulla oblongata [nTPM]":"25.4","Tissue RNA - midbrain [nTPM]":"22.6","Tissue RNA - ovary [nTPM]":"12.8","Tissue RNA - pancreas [nTPM]":"19.8","Tissue RNA - parathyroid gland [nTPM]":"10.4","Tissue RNA - pituitary gland [nTPM]":"18.5","Tissue RNA - placenta [nTPM]":"3.8","Tissue RNA - pons [nTPM]":"22.1","Tissue RNA - prostate [nTPM]":"16.1","Tissue RNA - rectum [nTPM]":"4.4","Tissue RNA - retina [nTPM]":"4.6","Tissue RNA - salivary gland [nTPM]":"14.3","Tissue RNA - seminal vesicle [nTPM]":"6.9","Tissue RNA - skeletal muscle [nTPM]":"18.6","Tissue RNA - skin 1 [nTPM]":"14.0","Tissue RNA - small intestine [nTPM]":"9.6","Tissue RNA - smooth muscle [nTPM]":"4.1","Tissue RNA - spinal cord [nTPM]":"23.4","Tissue RNA - spleen [nTPM]":"10.2","Tissue RNA - stomach 1 [nTPM]":"12.7","Tissue RNA - testis [nTPM]":"22.0","Tissue RNA - thalamus [nTPM]":"23.3","Tissue RNA - thymus [nTPM]":"3.7","Tissue RNA - thyroid gland [nTPM]":"13.1","Tissue RNA - tongue [nTPM]":"10.2","Tissue RNA - tonsil [nTPM]":"3.4","Tissue RNA - urinary bladder [nTPM]":"12.9","Tissue RNA - vagina [nTPM]":"11.3","Tissue RNA - white matter [nTPM]":"25.3","Cell RNA - A-431 [nTPM]":"18.6","Cell RNA - A549 [nTPM]":"16.9","Cell RNA - AF22 [nTPM]":"13.2","Cell RNA - AN3-CA [nTPM]":"7.4","Cell RNA - ASC diff [nTPM]":"7.9","Cell RNA - ASC TERT1 [nTPM]":"9.7","Cell RNA - BEWO [nTPM]":"11.5","Cell RNA - BJ [nTPM]":"9.6","Cell RNA - BJ hTERT+ [nTPM]":"10.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.3","Cell RNA - CACO-2 [nTPM]":"27.2","Cell RNA - CAPAN-2 [nTPM]":"13.9","Cell RNA - Daudi [nTPM]":"10.8","Cell RNA - EFO-21 [nTPM]":"27.1","Cell RNA - fHDF\/TERT166 [nTPM]":"11.9","Cell RNA - GAMG [nTPM]":"8.7","Cell RNA - HaCaT [nTPM]":"12.1","Cell RNA - HAP1 [nTPM]":"11.6","Cell RNA - HBEC3-KT [nTPM]":"16.3","Cell RNA - HBF TERT88 [nTPM]":"8.1","Cell RNA - HDLM-2 [nTPM]":"16.8","Cell RNA - HEK 293 [nTPM]":"21.9","Cell RNA - HEL [nTPM]":"8.5","Cell RNA - HeLa [nTPM]":"17.2","Cell RNA - Hep G2 [nTPM]":"55.3","Cell RNA - HHSteC [nTPM]":"16.4","Cell RNA - HL-60 [nTPM]":"14.2","Cell RNA - HMC-1 [nTPM]":"4.2","Cell RNA - HSkMC [nTPM]":"9.0","Cell RNA - hTCEpi [nTPM]":"9.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.8","Cell RNA - hTERT-HME1 [nTPM]":"16.0","Cell RNA - hTERT-RPE1 [nTPM]":"10.4","Cell RNA - HUVEC TERT2 [nTPM]":"13.9","Cell RNA - JURKAT [nTPM]":"12.5","Cell RNA - K-562 [nTPM]":"9.9","Cell RNA - Karpas-707 [nTPM]":"7.4","Cell RNA - LHCN-M2 [nTPM]":"14.7","Cell RNA - MCF7 [nTPM]":"26.2","Cell RNA - MOLT-4 [nTPM]":"9.1","Cell RNA - NB-4 [nTPM]":"6.0","Cell RNA - NTERA-2 [nTPM]":"9.6","Cell RNA - OE19 [nTPM]":"8.0","Cell RNA - PC-3 [nTPM]":"31.3","Cell RNA - REH [nTPM]":"7.8","Cell RNA - RH-30 [nTPM]":"13.8","Cell RNA - RPMI-8226 [nTPM]":"18.9","Cell RNA - RPTEC TERT1 [nTPM]":"17.8","Cell RNA - RT4 [nTPM]":"6.3","Cell RNA - SCLC-21H [nTPM]":"18.2","Cell RNA - SH-SY5Y [nTPM]":"15.3","Cell RNA - SiHa [nTPM]":"13.0","Cell RNA - SK-BR-3 [nTPM]":"8.2","Cell RNA - SK-MEL-30 [nTPM]":"29.2","Cell RNA - SuSa [nTPM]":"7.1","Cell RNA - T-47d [nTPM]":"8.3","Cell RNA - THP-1 [nTPM]":"3.5","Cell RNA - TIME [nTPM]":"14.8","Cell RNA - U-138 MG [nTPM]":"6.7","Cell RNA - U-2 OS [nTPM]":"5.9","Cell RNA - U-2197 [nTPM]":"17.2","Cell RNA - U-251 MG [nTPM]":"10.8","Cell RNA - U-266\/70 [nTPM]":"19.0","Cell RNA - U-266\/84 [nTPM]":"7.6","Cell RNA - U-698 [nTPM]":"8.6","Cell RNA - U-87 MG [nTPM]":"17.6","Cell RNA - U-937 [nTPM]":"10.9","Cell RNA - WM-115 [nTPM]":"6.1","Blood RNA - basophil [nTPM]":"1.6","Blood RNA - classical monocyte [nTPM]":"5.8","Blood RNA - eosinophil [nTPM]":"1.7","Blood RNA - gdT-cell [nTPM]":"3.8","Blood RNA - intermediate monocyte [nTPM]":"8.7","Blood RNA - MAIT T-cell [nTPM]":"4.4","Blood RNA - memory B-cell [nTPM]":"5.9","Blood RNA - memory CD4 T-cell [nTPM]":"3.3","Blood RNA - memory CD8 T-cell [nTPM]":"5.1","Blood RNA - myeloid DC [nTPM]":"9.4","Blood RNA - naive B-cell [nTPM]":"4.9","Blood RNA - naive CD4 T-cell [nTPM]":"3.8","Blood RNA - naive CD8 T-cell [nTPM]":"3.0","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"3.6","Blood RNA - non-classical monocyte [nTPM]":"7.6","Blood RNA - plasmacytoid DC [nTPM]":"7.8","Blood RNA - T-reg [nTPM]":"2.1","Blood RNA - total PBMC [nTPM]":"4.2","Brain RNA - amygdala [nTPM]":"22.2","Brain RNA - basal ganglia [nTPM]":"24.3","Brain RNA - cerebellum [nTPM]":"23.5","Brain RNA - cerebral cortex [nTPM]":"25.7","Brain RNA - hippocampal formation [nTPM]":"20.6","Brain RNA - hypothalamus [nTPM]":"21.6","Brain RNA - medulla oblongata [nTPM]":"25.4","Brain RNA - midbrain [nTPM]":"22.6","Brain RNA - pons [nTPM]":"22.1","Brain RNA - spinal cord [nTPM]":"23.4","Brain RNA - thalamus [nTPM]":"23.3","Brain RNA - white matter [nTPM]":"25.3","Single Cell Type RNA - Adipocytes [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.4","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"9.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Bipolar cells [nTPM]":"16.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"8.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"26.7","Single Cell Type RNA - dendritic cells [nTPM]":"6.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"26.8","Single Cell Type RNA - Early spermatids [nTPM]":"51.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.0","Single Cell Type RNA - Endothelial cells [nTPM]":"11.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.2","Single Cell Type RNA - Erythroid cells [nTPM]":"9.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"25.2","Single Cell Type RNA - Fibroblasts [nTPM]":"11.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"22.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"10.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.9","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.3","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"11.2","Single Cell Type RNA - Langerhans cells [nTPM]":"7.2","Single Cell Type RNA - Late spermatids [nTPM]":"194.7","Single Cell Type RNA - Leydig cells [nTPM]":"10.5","Single Cell Type RNA - Macrophages [nTPM]":"9.6","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"18.7","Single Cell Type RNA - Muller glia cells [nTPM]":"45.2","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.0","Single Cell Type RNA - Paneth cells [nTPM]":"7.7","Single Cell Type RNA - Peritubular cells [nTPM]":"13.5","Single Cell Type RNA - Plasma cells [nTPM]":"14.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"27.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.9","Single Cell Type RNA - Spermatocytes [nTPM]":"28.9","Single Cell Type RNA - Spermatogonia [nTPM]":"22.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"27.5","Single Cell Type RNA - T-cells [nTPM]":"6.9","Single Cell Type RNA - Theca cells [nTPM]":"30.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.6","Single Cell Type RNA - Urothelial cells [nTPM]":"14.1"},{"Gene":"PEX12","Gene synonym":[],"Ensembl":"ENSG00000108733","Gene description":"Peroxisomal biogenesis factor 12","Uniprot":["O00623"],"Chromosome":"17","Position":"35574795-35578863","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Peroxisome biogenesis disorder","Zellweger syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"17.2","Spermatocytes":"21.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069386"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA069386":"AB_2686135"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.58e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.9","Tissue RNA - adrenal gland [nTPM]":"6.8","Tissue RNA - amygdala [nTPM]":"6.7","Tissue RNA - appendix [nTPM]":"3.6","Tissue RNA - basal ganglia [nTPM]":"7.2","Tissue RNA - bone marrow [nTPM]":"1.5","Tissue RNA - breast [nTPM]":"5.5","Tissue RNA - cerebellum [nTPM]":"7.9","Tissue RNA - cerebral cortex [nTPM]":"9.1","Tissue RNA - cervix [nTPM]":"5.3","Tissue RNA - choroid plexus [nTPM]":"6.7","Tissue RNA - colon [nTPM]":"3.4","Tissue RNA - duodenum [nTPM]":"3.6","Tissue RNA - endometrium 1 [nTPM]":"4.3","Tissue RNA - epididymis [nTPM]":"10.7","Tissue RNA - esophagus [nTPM]":"3.4","Tissue RNA - fallopian tube [nTPM]":"5.6","Tissue RNA - gallbladder [nTPM]":"3.2","Tissue RNA - heart muscle [nTPM]":"9.1","Tissue RNA - hippocampal formation [nTPM]":"6.8","Tissue RNA - hypothalamus [nTPM]":"7.1","Tissue RNA - kidney [nTPM]":"8.2","Tissue RNA - liver [nTPM]":"9.0","Tissue RNA - lung [nTPM]":"3.4","Tissue RNA - lymph node [nTPM]":"4.8","Tissue RNA - medulla oblongata [nTPM]":"6.8","Tissue RNA - midbrain [nTPM]":"6.9","Tissue RNA - ovary [nTPM]":"8.2","Tissue RNA - pancreas [nTPM]":"4.0","Tissue RNA - parathyroid gland [nTPM]":"7.8","Tissue RNA - pituitary gland [nTPM]":"4.7","Tissue RNA - placenta [nTPM]":"4.7","Tissue RNA - pons [nTPM]":"6.8","Tissue RNA - prostate [nTPM]":"5.7","Tissue RNA - rectum [nTPM]":"2.9","Tissue RNA - retina [nTPM]":"4.6","Tissue RNA - salivary gland [nTPM]":"5.5","Tissue RNA - seminal vesicle [nTPM]":"6.9","Tissue RNA - skeletal muscle [nTPM]":"10.3","Tissue RNA - skin 1 [nTPM]":"4.2","Tissue RNA - small intestine [nTPM]":"3.5","Tissue RNA - smooth muscle [nTPM]":"3.5","Tissue RNA - spinal cord [nTPM]":"7.3","Tissue RNA - spleen [nTPM]":"3.9","Tissue RNA - stomach 1 [nTPM]":"3.9","Tissue RNA - testis [nTPM]":"6.8","Tissue RNA - thalamus [nTPM]":"7.0","Tissue RNA - thymus [nTPM]":"3.2","Tissue RNA - thyroid gland [nTPM]":"7.7","Tissue RNA - tongue [nTPM]":"10.8","Tissue RNA - tonsil [nTPM]":"4.5","Tissue RNA - urinary bladder [nTPM]":"3.7","Tissue RNA - vagina [nTPM]":"2.7","Tissue RNA - white matter [nTPM]":"8.4","Cell RNA - A-431 [nTPM]":"2.8","Cell RNA - A549 [nTPM]":"3.7","Cell RNA - AF22 [nTPM]":"5.4","Cell RNA - AN3-CA [nTPM]":"4.4","Cell RNA - ASC diff [nTPM]":"11.0","Cell RNA - ASC TERT1 [nTPM]":"9.9","Cell RNA - BEWO [nTPM]":"3.9","Cell RNA - BJ [nTPM]":"7.3","Cell RNA - BJ hTERT+ [nTPM]":"8.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.3","Cell RNA - CACO-2 [nTPM]":"3.2","Cell RNA - CAPAN-2 [nTPM]":"3.0","Cell RNA - Daudi [nTPM]":"6.4","Cell RNA - EFO-21 [nTPM]":"11.6","Cell RNA - fHDF\/TERT166 [nTPM]":"4.1","Cell RNA - GAMG [nTPM]":"4.9","Cell RNA - HaCaT [nTPM]":"7.3","Cell RNA - HAP1 [nTPM]":"6.6","Cell RNA - HBEC3-KT [nTPM]":"4.8","Cell RNA - HBF TERT88 [nTPM]":"5.2","Cell RNA - HDLM-2 [nTPM]":"2.3","Cell RNA - HEK 293 [nTPM]":"8.7","Cell RNA - HEL [nTPM]":"4.7","Cell RNA - HeLa [nTPM]":"3.8","Cell RNA - Hep G2 [nTPM]":"5.9","Cell RNA - HHSteC [nTPM]":"12.8","Cell RNA - HL-60 [nTPM]":"6.7","Cell RNA - HMC-1 [nTPM]":"1.2","Cell RNA - HSkMC [nTPM]":"9.2","Cell RNA - hTCEpi [nTPM]":"9.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.7","Cell RNA - hTERT-HME1 [nTPM]":"10.9","Cell RNA - hTERT-RPE1 [nTPM]":"7.7","Cell RNA - HUVEC TERT2 [nTPM]":"4.6","Cell RNA - JURKAT [nTPM]":"5.2","Cell RNA - K-562 [nTPM]":"7.5","Cell RNA - Karpas-707 [nTPM]":"6.6","Cell RNA - LHCN-M2 [nTPM]":"7.2","Cell RNA - MCF7 [nTPM]":"2.9","Cell RNA - MOLT-4 [nTPM]":"7.9","Cell RNA - NB-4 [nTPM]":"3.8","Cell RNA - NTERA-2 [nTPM]":"2.2","Cell RNA - OE19 [nTPM]":"6.3","Cell RNA - PC-3 [nTPM]":"5.8","Cell RNA - REH [nTPM]":"3.8","Cell RNA - RH-30 [nTPM]":"9.3","Cell RNA - RPMI-8226 [nTPM]":"6.4","Cell RNA - RPTEC TERT1 [nTPM]":"7.1","Cell RNA - RT4 [nTPM]":"4.2","Cell RNA - SCLC-21H [nTPM]":"4.0","Cell RNA - SH-SY5Y [nTPM]":"4.0","Cell RNA - SiHa [nTPM]":"4.6","Cell RNA - SK-BR-3 [nTPM]":"3.0","Cell RNA - SK-MEL-30 [nTPM]":"9.6","Cell RNA - SuSa [nTPM]":"6.5","Cell RNA - T-47d [nTPM]":"7.4","Cell RNA - THP-1 [nTPM]":"3.7","Cell RNA - TIME [nTPM]":"3.7","Cell RNA - U-138 MG [nTPM]":"5.6","Cell RNA - U-2 OS [nTPM]":"3.5","Cell RNA - U-2197 [nTPM]":"6.3","Cell RNA - U-251 MG [nTPM]":"4.9","Cell RNA - U-266\/70 [nTPM]":"13.3","Cell RNA - U-266\/84 [nTPM]":"9.9","Cell RNA - U-698 [nTPM]":"7.5","Cell RNA - U-87 MG [nTPM]":"6.0","Cell RNA - U-937 [nTPM]":"5.1","Cell RNA - WM-115 [nTPM]":"5.2","Blood RNA - basophil [nTPM]":"2.2","Blood RNA - classical monocyte [nTPM]":"1.5","Blood RNA - eosinophil [nTPM]":"3.0","Blood RNA - gdT-cell [nTPM]":"1.8","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"3.2","Blood RNA - memory B-cell [nTPM]":"2.3","Blood RNA - memory CD4 T-cell [nTPM]":"3.0","Blood RNA - memory CD8 T-cell [nTPM]":"1.8","Blood RNA - myeloid DC [nTPM]":"1.7","Blood RNA - naive B-cell [nTPM]":"2.6","Blood RNA - naive CD4 T-cell [nTPM]":"4.1","Blood RNA - naive CD8 T-cell [nTPM]":"3.5","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"2.0","Blood RNA - non-classical monocyte [nTPM]":"1.2","Blood RNA - plasmacytoid DC [nTPM]":"1.7","Blood RNA - T-reg [nTPM]":"2.4","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"6.7","Brain RNA - basal ganglia [nTPM]":"7.2","Brain RNA - cerebellum [nTPM]":"7.9","Brain RNA - cerebral cortex [nTPM]":"9.1","Brain RNA - hippocampal formation [nTPM]":"6.8","Brain RNA - hypothalamus [nTPM]":"7.1","Brain RNA - medulla oblongata [nTPM]":"6.8","Brain RNA - midbrain [nTPM]":"6.9","Brain RNA - pons [nTPM]":"6.8","Brain RNA - spinal cord [nTPM]":"7.3","Brain RNA - thalamus [nTPM]":"7.0","Brain RNA - white matter [nTPM]":"8.4","Single Cell Type RNA - Adipocytes [nTPM]":"2.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"6.5","Single Cell Type RNA - B-cells [nTPM]":"3.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"2.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.7","Single Cell Type RNA - dendritic cells [nTPM]":"1.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.5","Single Cell Type RNA - Early spermatids [nTPM]":"17.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.3","Single Cell Type RNA - Endothelial cells [nTPM]":"3.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.1","Single Cell Type RNA - Fibroblasts [nTPM]":"2.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.5","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"2.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"5.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.9","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.7","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.6","Single Cell Type RNA - Late spermatids [nTPM]":"3.0","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"1.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.9","Single Cell Type RNA - Muller glia cells [nTPM]":"8.3","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.2","Single Cell Type RNA - Paneth cells [nTPM]":"1.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"0.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.7","Single Cell Type RNA - Spermatocytes [nTPM]":"21.0","Single Cell Type RNA - Spermatogonia [nTPM]":"10.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.2","Single Cell Type RNA - T-cells [nTPM]":"2.8","Single Cell Type RNA - Theca cells [nTPM]":"3.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.2","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"PEX13","Gene synonym":[],"Ensembl":"ENSG00000162928","Gene description":"Peroxisomal biogenesis factor 13","Uniprot":["Q92968"],"Chromosome":"2","Position":"61017225-61051990","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Peroxisome biogenesis disorder","Zellweger syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"125.8","Urothelial cells":"112.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032141","HPA032142","CAB032689"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Peroxisomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Peroxisomes"],"Subcellular additional location":null,"Antibody RRID":{"CAB032689":"AB_2162137","HPA032141":"AB_2674176","HPA032142":"AB_10669676"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.07e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.5","Tissue RNA - adrenal gland [nTPM]":"8.0","Tissue RNA - amygdala [nTPM]":"6.6","Tissue RNA - appendix [nTPM]":"6.7","Tissue RNA - basal ganglia [nTPM]":"7.1","Tissue RNA - bone marrow [nTPM]":"7.4","Tissue RNA - breast [nTPM]":"11.1","Tissue RNA - cerebellum [nTPM]":"9.7","Tissue RNA - cerebral cortex [nTPM]":"9.2","Tissue RNA - cervix [nTPM]":"10.2","Tissue RNA - choroid plexus [nTPM]":"10.2","Tissue RNA - colon [nTPM]":"10.2","Tissue RNA - duodenum [nTPM]":"10.2","Tissue RNA - endometrium 1 [nTPM]":"9.2","Tissue RNA - epididymis [nTPM]":"7.5","Tissue RNA - esophagus [nTPM]":"10.2","Tissue RNA - fallopian tube [nTPM]":"6.6","Tissue RNA - gallbladder [nTPM]":"8.8","Tissue RNA - heart muscle [nTPM]":"11.9","Tissue RNA - hippocampal formation [nTPM]":"6.8","Tissue RNA - hypothalamus [nTPM]":"7.4","Tissue RNA - kidney [nTPM]":"13.6","Tissue RNA - liver [nTPM]":"25.0","Tissue RNA - lung [nTPM]":"9.3","Tissue RNA - lymph node [nTPM]":"6.8","Tissue RNA - medulla oblongata [nTPM]":"6.7","Tissue RNA - midbrain [nTPM]":"7.1","Tissue RNA - ovary [nTPM]":"11.0","Tissue RNA - pancreas [nTPM]":"11.8","Tissue RNA - parathyroid gland [nTPM]":"9.6","Tissue RNA - pituitary gland [nTPM]":"7.4","Tissue RNA - placenta [nTPM]":"9.3","Tissue RNA - pons [nTPM]":"6.8","Tissue RNA - prostate [nTPM]":"14.6","Tissue RNA - rectum [nTPM]":"10.7","Tissue RNA - retina [nTPM]":"8.8","Tissue RNA - salivary gland [nTPM]":"8.7","Tissue RNA - seminal vesicle [nTPM]":"5.8","Tissue RNA - skeletal muscle [nTPM]":"14.6","Tissue RNA - skin 1 [nTPM]":"7.9","Tissue RNA - small intestine [nTPM]":"9.8","Tissue RNA - smooth muscle [nTPM]":"8.1","Tissue RNA - spinal cord [nTPM]":"6.6","Tissue RNA - spleen [nTPM]":"6.7","Tissue RNA - stomach 1 [nTPM]":"10.1","Tissue RNA - testis [nTPM]":"14.9","Tissue RNA - thalamus [nTPM]":"7.1","Tissue RNA - thymus [nTPM]":"7.3","Tissue RNA - thyroid gland [nTPM]":"13.7","Tissue RNA - tongue [nTPM]":"13.6","Tissue RNA - tonsil [nTPM]":"6.7","Tissue RNA - urinary bladder [nTPM]":"13.8","Tissue RNA - vagina [nTPM]":"9.1","Tissue RNA - white matter [nTPM]":"7.7","Cell RNA - A-431 [nTPM]":"15.5","Cell RNA - A549 [nTPM]":"11.3","Cell RNA - AF22 [nTPM]":"15.7","Cell RNA - AN3-CA [nTPM]":"20.3","Cell RNA - ASC diff [nTPM]":"14.8","Cell RNA - ASC TERT1 [nTPM]":"11.5","Cell RNA - BEWO [nTPM]":"24.2","Cell RNA - BJ [nTPM]":"15.9","Cell RNA - BJ hTERT+ [nTPM]":"12.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.8","Cell RNA - CACO-2 [nTPM]":"16.9","Cell RNA - CAPAN-2 [nTPM]":"22.9","Cell RNA - Daudi [nTPM]":"10.0","Cell RNA - EFO-21 [nTPM]":"16.7","Cell RNA - fHDF\/TERT166 [nTPM]":"15.6","Cell RNA - GAMG [nTPM]":"19.9","Cell RNA - HaCaT [nTPM]":"22.8","Cell RNA - HAP1 [nTPM]":"14.1","Cell RNA - HBEC3-KT [nTPM]":"19.2","Cell RNA - HBF TERT88 [nTPM]":"20.0","Cell RNA - HDLM-2 [nTPM]":"9.9","Cell RNA - HEK 293 [nTPM]":"9.7","Cell RNA - HEL [nTPM]":"9.2","Cell RNA - HeLa [nTPM]":"15.1","Cell RNA - Hep G2 [nTPM]":"28.0","Cell RNA - HHSteC [nTPM]":"17.5","Cell RNA - HL-60 [nTPM]":"13.9","Cell RNA - HMC-1 [nTPM]":"10.8","Cell RNA - HSkMC [nTPM]":"14.2","Cell RNA - hTCEpi [nTPM]":"28.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.5","Cell RNA - hTERT-HME1 [nTPM]":"22.3","Cell RNA - hTERT-RPE1 [nTPM]":"16.2","Cell RNA - HUVEC TERT2 [nTPM]":"19.4","Cell RNA - JURKAT [nTPM]":"11.3","Cell RNA - K-562 [nTPM]":"22.8","Cell RNA - Karpas-707 [nTPM]":"8.7","Cell RNA - LHCN-M2 [nTPM]":"16.3","Cell RNA - MCF7 [nTPM]":"14.1","Cell RNA - MOLT-4 [nTPM]":"10.4","Cell RNA - NB-4 [nTPM]":"16.6","Cell RNA - NTERA-2 [nTPM]":"17.2","Cell RNA - OE19 [nTPM]":"28.6","Cell RNA - PC-3 [nTPM]":"11.2","Cell RNA - REH [nTPM]":"11.1","Cell RNA - RH-30 [nTPM]":"17.4","Cell RNA - RPMI-8226 [nTPM]":"12.7","Cell RNA - RPTEC TERT1 [nTPM]":"20.3","Cell RNA - RT4 [nTPM]":"38.2","Cell RNA - SCLC-21H [nTPM]":"17.7","Cell RNA - SH-SY5Y [nTPM]":"12.2","Cell RNA - SiHa [nTPM]":"17.7","Cell RNA - SK-BR-3 [nTPM]":"23.7","Cell RNA - SK-MEL-30 [nTPM]":"14.9","Cell RNA - SuSa [nTPM]":"18.5","Cell RNA - T-47d [nTPM]":"15.8","Cell RNA - THP-1 [nTPM]":"7.1","Cell RNA - TIME [nTPM]":"15.3","Cell RNA - U-138 MG [nTPM]":"20.2","Cell RNA - U-2 OS [nTPM]":"27.0","Cell RNA - U-2197 [nTPM]":"11.8","Cell RNA - U-251 MG [nTPM]":"13.6","Cell RNA - U-266\/70 [nTPM]":"14.2","Cell RNA - U-266\/84 [nTPM]":"11.6","Cell RNA - U-698 [nTPM]":"25.0","Cell RNA - U-87 MG [nTPM]":"12.7","Cell RNA - U-937 [nTPM]":"14.0","Cell RNA - WM-115 [nTPM]":"14.5","Blood RNA - basophil [nTPM]":"12.4","Blood RNA - classical monocyte [nTPM]":"3.9","Blood RNA - eosinophil [nTPM]":"5.9","Blood RNA - gdT-cell [nTPM]":"5.0","Blood RNA - intermediate monocyte [nTPM]":"3.9","Blood RNA - MAIT T-cell [nTPM]":"4.7","Blood RNA - memory B-cell [nTPM]":"5.4","Blood RNA - memory CD4 T-cell [nTPM]":"5.8","Blood RNA - memory CD8 T-cell [nTPM]":"5.5","Blood RNA - myeloid DC [nTPM]":"5.1","Blood RNA - naive B-cell [nTPM]":"4.1","Blood RNA - naive CD4 T-cell [nTPM]":"6.1","Blood RNA - naive CD8 T-cell [nTPM]":"4.6","Blood RNA - neutrophil [nTPM]":"3.7","Blood RNA - NK-cell [nTPM]":"5.5","Blood RNA - non-classical monocyte [nTPM]":"5.0","Blood RNA - plasmacytoid DC [nTPM]":"4.5","Blood RNA - T-reg [nTPM]":"5.4","Blood RNA - total PBMC [nTPM]":"3.9","Brain RNA - amygdala [nTPM]":"6.6","Brain RNA - basal ganglia [nTPM]":"7.1","Brain RNA - cerebellum [nTPM]":"9.7","Brain RNA - cerebral cortex [nTPM]":"9.2","Brain RNA - hippocampal formation [nTPM]":"6.8","Brain RNA - hypothalamus [nTPM]":"7.4","Brain RNA - medulla oblongata [nTPM]":"6.7","Brain RNA - midbrain [nTPM]":"7.1","Brain RNA - pons [nTPM]":"6.8","Brain RNA - spinal cord [nTPM]":"6.6","Brain RNA - thalamus [nTPM]":"7.1","Brain RNA - white matter [nTPM]":"7.7","Single Cell Type RNA - Adipocytes [nTPM]":"12.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.1","Single Cell Type RNA - Astrocytes [nTPM]":"14.0","Single Cell Type RNA - B-cells [nTPM]":"13.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"51.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"35.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"61.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.6","Single Cell Type RNA - Bipolar cells [nTPM]":"11.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"21.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"28.6","Single Cell Type RNA - Club cells [nTPM]":"53.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"36.9","Single Cell Type RNA - dendritic cells [nTPM]":"13.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"27.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"25.4","Single Cell Type RNA - Ductal cells [nTPM]":"28.8","Single Cell Type RNA - Early spermatids [nTPM]":"125.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"24.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.1","Single Cell Type RNA - Endothelial cells [nTPM]":"15.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"9.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"28.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"43.1","Single Cell Type RNA - Fibroblasts [nTPM]":"14.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"28.8","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"15.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"49.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.9","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"16.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.5","Single Cell Type RNA - Ionocytes [nTPM]":"36.7","Single Cell Type RNA - Kupffer cells [nTPM]":"14.6","Single Cell Type RNA - Langerhans cells [nTPM]":"25.9","Single Cell Type RNA - Late spermatids [nTPM]":"28.7","Single Cell Type RNA - Leydig cells [nTPM]":"9.6","Single Cell Type RNA - Macrophages [nTPM]":"14.8","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"25.3","Single Cell Type RNA - monocytes [nTPM]":"19.3","Single Cell Type RNA - Muller glia cells [nTPM]":"12.6","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"23.2","Single Cell Type RNA - Paneth cells [nTPM]":"13.2","Single Cell Type RNA - Peritubular cells [nTPM]":"11.7","Single Cell Type RNA - Plasma cells [nTPM]":"9.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"43.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"28.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"38.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.8","Single Cell Type RNA - Spermatocytes [nTPM]":"66.8","Single Cell Type RNA - Spermatogonia [nTPM]":"26.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"50.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"68.7","Single Cell Type RNA - T-cells [nTPM]":"15.0","Single Cell Type RNA - Theca cells [nTPM]":"11.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.1","Single Cell Type RNA - Urothelial cells [nTPM]":"112.0"},{"Gene":"PEX14","Gene synonym":[],"Ensembl":"ENSG00000142655","Gene description":"Peroxisomal biogenesis factor 14","Uniprot":["O75381"],"Chromosome":"1","Position":"10472288-10630758","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Peroxisome biogenesis disorder","Zellweger syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"67.3","Syncytiotrophoblasts":"64.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046104","HPA049231"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli fibrillar center","Peroxisomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Peroxisomes"],"Subcellular additional location":["Nucleoli fibrillar center"],"Antibody RRID":{"HPA046104":"AB_2679539","HPA049231":"AB_2680683"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.67e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.9","Tissue RNA - adrenal gland [nTPM]":"13.9","Tissue RNA - amygdala [nTPM]":"15.5","Tissue RNA - appendix [nTPM]":"9.5","Tissue RNA - basal ganglia [nTPM]":"15.3","Tissue RNA - bone marrow [nTPM]":"7.8","Tissue RNA - breast [nTPM]":"16.2","Tissue RNA - cerebellum [nTPM]":"11.7","Tissue RNA - cerebral cortex [nTPM]":"21.8","Tissue RNA - cervix [nTPM]":"15.5","Tissue RNA - choroid plexus [nTPM]":"10.7","Tissue RNA - colon [nTPM]":"16.8","Tissue RNA - duodenum [nTPM]":"15.1","Tissue RNA - endometrium 1 [nTPM]":"17.1","Tissue RNA - epididymis [nTPM]":"6.4","Tissue RNA - esophagus [nTPM]":"20.9","Tissue RNA - fallopian tube [nTPM]":"13.7","Tissue RNA - gallbladder [nTPM]":"9.3","Tissue RNA - heart muscle [nTPM]":"19.6","Tissue RNA - hippocampal formation [nTPM]":"15.8","Tissue RNA - hypothalamus [nTPM]":"13.6","Tissue RNA - kidney [nTPM]":"15.8","Tissue RNA - liver [nTPM]":"33.0","Tissue RNA - lung [nTPM]":"14.3","Tissue RNA - lymph node [nTPM]":"10.5","Tissue RNA - medulla oblongata [nTPM]":"14.1","Tissue RNA - midbrain [nTPM]":"13.1","Tissue RNA - ovary [nTPM]":"14.9","Tissue RNA - pancreas [nTPM]":"11.2","Tissue RNA - parathyroid gland [nTPM]":"11.8","Tissue RNA - pituitary gland [nTPM]":"14.1","Tissue RNA - placenta [nTPM]":"11.8","Tissue RNA - pons [nTPM]":"13.8","Tissue RNA - prostate [nTPM]":"26.4","Tissue RNA - rectum [nTPM]":"8.2","Tissue RNA - retina [nTPM]":"28.1","Tissue RNA - salivary gland [nTPM]":"16.8","Tissue RNA - seminal vesicle [nTPM]":"23.8","Tissue RNA - skeletal muscle [nTPM]":"22.6","Tissue RNA - skin 1 [nTPM]":"18.6","Tissue RNA - small intestine [nTPM]":"16.2","Tissue RNA - smooth muscle [nTPM]":"8.5","Tissue RNA - spinal cord [nTPM]":"12.2","Tissue RNA - spleen [nTPM]":"12.6","Tissue RNA - stomach 1 [nTPM]":"13.8","Tissue RNA - testis [nTPM]":"14.0","Tissue RNA - thalamus [nTPM]":"14.3","Tissue RNA - thymus [nTPM]":"9.7","Tissue RNA - thyroid gland [nTPM]":"14.0","Tissue RNA - tongue [nTPM]":"11.3","Tissue RNA - tonsil [nTPM]":"8.6","Tissue RNA - urinary bladder [nTPM]":"48.8","Tissue RNA - vagina [nTPM]":"17.6","Tissue RNA - white matter [nTPM]":"16.0","Cell RNA - A-431 [nTPM]":"22.5","Cell RNA - A549 [nTPM]":"21.1","Cell RNA - AF22 [nTPM]":"17.2","Cell RNA - AN3-CA [nTPM]":"19.2","Cell RNA - ASC diff [nTPM]":"12.3","Cell RNA - ASC TERT1 [nTPM]":"11.6","Cell RNA - BEWO [nTPM]":"11.2","Cell RNA - BJ [nTPM]":"25.2","Cell RNA - BJ hTERT+ [nTPM]":"20.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"27.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"26.1","Cell RNA - CACO-2 [nTPM]":"22.4","Cell RNA - CAPAN-2 [nTPM]":"40.1","Cell RNA - Daudi [nTPM]":"16.4","Cell RNA - EFO-21 [nTPM]":"24.9","Cell RNA - fHDF\/TERT166 [nTPM]":"19.4","Cell RNA - GAMG [nTPM]":"16.3","Cell RNA - HaCaT [nTPM]":"26.3","Cell RNA - HAP1 [nTPM]":"17.9","Cell RNA - HBEC3-KT [nTPM]":"24.6","Cell RNA - HBF TERT88 [nTPM]":"12.9","Cell RNA - HDLM-2 [nTPM]":"23.1","Cell RNA - HEK 293 [nTPM]":"30.3","Cell RNA - HEL [nTPM]":"20.4","Cell RNA - HeLa [nTPM]":"22.6","Cell RNA - Hep G2 [nTPM]":"31.2","Cell RNA - HHSteC [nTPM]":"18.8","Cell RNA - HL-60 [nTPM]":"23.0","Cell RNA - HMC-1 [nTPM]":"27.3","Cell RNA - HSkMC [nTPM]":"14.2","Cell RNA - hTCEpi [nTPM]":"19.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.7","Cell RNA - hTERT-HME1 [nTPM]":"19.0","Cell RNA - hTERT-RPE1 [nTPM]":"16.3","Cell RNA - HUVEC TERT2 [nTPM]":"17.9","Cell RNA - JURKAT [nTPM]":"21.2","Cell RNA - K-562 [nTPM]":"32.2","Cell RNA - Karpas-707 [nTPM]":"16.3","Cell RNA - LHCN-M2 [nTPM]":"12.4","Cell RNA - MCF7 [nTPM]":"18.7","Cell RNA - MOLT-4 [nTPM]":"21.9","Cell RNA - NB-4 [nTPM]":"30.4","Cell RNA - NTERA-2 [nTPM]":"17.7","Cell RNA - OE19 [nTPM]":"17.2","Cell RNA - PC-3 [nTPM]":"24.6","Cell RNA - REH [nTPM]":"23.5","Cell RNA - RH-30 [nTPM]":"14.5","Cell RNA - RPMI-8226 [nTPM]":"23.3","Cell RNA - RPTEC TERT1 [nTPM]":"21.7","Cell RNA - RT4 [nTPM]":"14.8","Cell RNA - SCLC-21H [nTPM]":"20.5","Cell RNA - SH-SY5Y [nTPM]":"23.5","Cell RNA - SiHa [nTPM]":"24.4","Cell RNA - SK-BR-3 [nTPM]":"20.2","Cell RNA - SK-MEL-30 [nTPM]":"23.9","Cell RNA - SuSa [nTPM]":"13.2","Cell RNA - T-47d [nTPM]":"18.4","Cell RNA - THP-1 [nTPM]":"16.2","Cell RNA - TIME [nTPM]":"17.7","Cell RNA - U-138 MG [nTPM]":"19.9","Cell RNA - U-2 OS [nTPM]":"21.5","Cell RNA - U-2197 [nTPM]":"19.6","Cell RNA - U-251 MG [nTPM]":"22.0","Cell RNA - U-266\/70 [nTPM]":"23.3","Cell RNA - U-266\/84 [nTPM]":"20.4","Cell RNA - U-698 [nTPM]":"32.3","Cell RNA - U-87 MG [nTPM]":"21.8","Cell RNA - U-937 [nTPM]":"31.2","Cell RNA - WM-115 [nTPM]":"21.7","Blood RNA - basophil [nTPM]":"1.4","Blood RNA - classical monocyte [nTPM]":"2.2","Blood RNA - eosinophil [nTPM]":"4.6","Blood RNA - gdT-cell [nTPM]":"4.5","Blood RNA - intermediate monocyte [nTPM]":"1.6","Blood RNA - MAIT T-cell [nTPM]":"2.8","Blood RNA - memory B-cell [nTPM]":"2.2","Blood RNA - memory CD4 T-cell [nTPM]":"2.3","Blood RNA - memory CD8 T-cell [nTPM]":"3.4","Blood RNA - myeloid DC [nTPM]":"2.7","Blood RNA - naive B-cell [nTPM]":"2.0","Blood RNA - naive CD4 T-cell [nTPM]":"2.9","Blood RNA - naive CD8 T-cell [nTPM]":"2.8","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"2.6","Blood RNA - non-classical monocyte [nTPM]":"1.5","Blood RNA - plasmacytoid DC [nTPM]":"2.8","Blood RNA - T-reg [nTPM]":"3.0","Blood RNA - total PBMC [nTPM]":"2.4","Brain RNA - amygdala [nTPM]":"15.5","Brain RNA - basal ganglia [nTPM]":"15.3","Brain RNA - cerebellum [nTPM]":"11.7","Brain RNA - cerebral cortex [nTPM]":"21.8","Brain RNA - hippocampal formation [nTPM]":"15.8","Brain RNA - hypothalamus [nTPM]":"13.6","Brain RNA - medulla oblongata [nTPM]":"14.1","Brain RNA - midbrain [nTPM]":"13.1","Brain RNA - pons [nTPM]":"13.8","Brain RNA - spinal cord [nTPM]":"12.2","Brain RNA - thalamus [nTPM]":"14.3","Brain RNA - white matter [nTPM]":"16.0","Single Cell Type RNA - Adipocytes [nTPM]":"5.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.0","Single Cell Type RNA - Astrocytes [nTPM]":"32.0","Single Cell Type RNA - B-cells [nTPM]":"9.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"15.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"12.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"49.7","Single Cell Type RNA - dendritic cells [nTPM]":"11.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"17.2","Single Cell Type RNA - Early spermatids [nTPM]":"5.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.9","Single Cell Type RNA - Endothelial cells [nTPM]":"7.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.0","Single Cell Type RNA - Erythroid cells [nTPM]":"4.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"42.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.7","Single Cell Type RNA - Fibroblasts [nTPM]":"8.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.4","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"7.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.2","Single Cell Type RNA - Hepatocytes [nTPM]":"51.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.7","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"48.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.7","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"9.0","Single Cell Type RNA - Langerhans cells [nTPM]":"3.1","Single Cell Type RNA - Late spermatids [nTPM]":"3.1","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"8.0","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"28.1","Single Cell Type RNA - monocytes [nTPM]":"19.9","Single Cell Type RNA - Muller glia cells [nTPM]":"21.2","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"29.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"29.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.2","Single Cell Type RNA - Paneth cells [nTPM]":"12.3","Single Cell Type RNA - Peritubular cells [nTPM]":"5.7","Single Cell Type RNA - Plasma cells [nTPM]":"14.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"29.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"67.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.0","Single Cell Type RNA - Spermatocytes [nTPM]":"7.1","Single Cell Type RNA - Spermatogonia [nTPM]":"12.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"64.7","Single Cell Type RNA - T-cells [nTPM]":"9.8","Single Cell Type RNA - Theca cells [nTPM]":"8.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.0","Single Cell Type RNA - Urothelial cells [nTPM]":"13.5"},{"Gene":"PEX16","Gene synonym":[],"Ensembl":"ENSG00000121680","Gene description":"Peroxisomal biogenesis factor 16","Uniprot":["Q9Y5Y5"],"Chromosome":"11","Position":"45909663-45918812","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Peroxisome biogenesis"],"Molecular function":null,"Disease involvement":["Disease variant","Peroxisome biogenesis disorder","Zellweger syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043286"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 1: Pancreatic cells - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043286":"AB_10794179"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.06e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.06e-4"},"Tissue RNA - adipose tissue [nTPM]":"23.4","Tissue RNA - adrenal gland [nTPM]":"27.1","Tissue RNA - amygdala [nTPM]":"22.3","Tissue RNA - appendix [nTPM]":"10.9","Tissue RNA - basal ganglia [nTPM]":"23.8","Tissue RNA - bone marrow [nTPM]":"20.3","Tissue RNA - breast [nTPM]":"22.2","Tissue RNA - cerebellum [nTPM]":"23.4","Tissue RNA - cerebral cortex [nTPM]":"24.4","Tissue RNA - cervix [nTPM]":"18.2","Tissue RNA - choroid plexus [nTPM]":"16.6","Tissue RNA - colon [nTPM]":"20.6","Tissue RNA - duodenum [nTPM]":"21.3","Tissue RNA - endometrium 1 [nTPM]":"18.7","Tissue RNA - epididymis [nTPM]":"6.3","Tissue RNA - esophagus [nTPM]":"21.3","Tissue RNA - fallopian tube [nTPM]":"18.9","Tissue RNA - gallbladder [nTPM]":"10.1","Tissue RNA - heart muscle [nTPM]":"17.0","Tissue RNA - hippocampal formation [nTPM]":"23.0","Tissue RNA - hypothalamus [nTPM]":"22.7","Tissue RNA - kidney [nTPM]":"26.7","Tissue RNA - liver [nTPM]":"50.2","Tissue RNA - lung [nTPM]":"16.2","Tissue RNA - lymph node [nTPM]":"16.6","Tissue RNA - medulla oblongata [nTPM]":"26.2","Tissue RNA - midbrain [nTPM]":"23.6","Tissue RNA - ovary [nTPM]":"18.3","Tissue RNA - pancreas [nTPM]":"40.0","Tissue RNA - parathyroid gland [nTPM]":"10.1","Tissue RNA - pituitary gland [nTPM]":"32.0","Tissue RNA - placenta [nTPM]":"6.7","Tissue RNA - pons [nTPM]":"23.2","Tissue RNA - prostate [nTPM]":"21.7","Tissue RNA - rectum [nTPM]":"5.1","Tissue RNA - retina [nTPM]":"4.4","Tissue RNA - salivary gland [nTPM]":"21.6","Tissue RNA - seminal vesicle [nTPM]":"9.7","Tissue RNA - skeletal muscle [nTPM]":"18.1","Tissue RNA - skin 1 [nTPM]":"27.2","Tissue RNA - small intestine [nTPM]":"25.3","Tissue RNA - smooth muscle [nTPM]":"6.0","Tissue RNA - spinal cord [nTPM]":"21.9","Tissue RNA - spleen [nTPM]":"24.5","Tissue RNA - stomach 1 [nTPM]":"27.6","Tissue RNA - testis [nTPM]":"25.8","Tissue RNA - thalamus [nTPM]":"23.6","Tissue RNA - thymus [nTPM]":"11.8","Tissue RNA - thyroid gland [nTPM]":"21.8","Tissue RNA - tongue [nTPM]":"7.5","Tissue RNA - tonsil [nTPM]":"8.6","Tissue RNA - urinary bladder [nTPM]":"20.1","Tissue RNA - vagina [nTPM]":"18.0","Tissue RNA - white matter [nTPM]":"26.0","Cell RNA - A-431 [nTPM]":"15.0","Cell RNA - A549 [nTPM]":"19.9","Cell RNA - AF22 [nTPM]":"6.7","Cell RNA - AN3-CA [nTPM]":"16.8","Cell RNA - ASC diff [nTPM]":"11.0","Cell RNA - ASC TERT1 [nTPM]":"13.2","Cell RNA - BEWO [nTPM]":"19.4","Cell RNA - BJ [nTPM]":"11.6","Cell RNA - BJ hTERT+ [nTPM]":"15.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.0","Cell RNA - CACO-2 [nTPM]":"22.6","Cell RNA - CAPAN-2 [nTPM]":"10.7","Cell RNA - Daudi [nTPM]":"25.6","Cell RNA - EFO-21 [nTPM]":"15.0","Cell RNA - fHDF\/TERT166 [nTPM]":"10.9","Cell RNA - GAMG [nTPM]":"14.7","Cell RNA - HaCaT [nTPM]":"27.2","Cell RNA - HAP1 [nTPM]":"6.9","Cell RNA - HBEC3-KT [nTPM]":"23.0","Cell RNA - HBF TERT88 [nTPM]":"3.7","Cell RNA - HDLM-2 [nTPM]":"22.4","Cell RNA - HEK 293 [nTPM]":"23.6","Cell RNA - HEL [nTPM]":"16.7","Cell RNA - HeLa [nTPM]":"28.8","Cell RNA - Hep G2 [nTPM]":"20.1","Cell RNA - HHSteC [nTPM]":"34.8","Cell RNA - HL-60 [nTPM]":"24.9","Cell RNA - HMC-1 [nTPM]":"33.8","Cell RNA - HSkMC [nTPM]":"21.3","Cell RNA - hTCEpi [nTPM]":"20.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.4","Cell RNA - hTERT-HME1 [nTPM]":"15.1","Cell RNA - hTERT-RPE1 [nTPM]":"9.1","Cell RNA - HUVEC TERT2 [nTPM]":"17.0","Cell RNA - JURKAT [nTPM]":"21.9","Cell RNA - K-562 [nTPM]":"13.4","Cell RNA - Karpas-707 [nTPM]":"29.6","Cell RNA - LHCN-M2 [nTPM]":"10.7","Cell RNA - MCF7 [nTPM]":"42.0","Cell RNA - MOLT-4 [nTPM]":"21.3","Cell RNA - NB-4 [nTPM]":"32.5","Cell RNA - NTERA-2 [nTPM]":"15.1","Cell RNA - OE19 [nTPM]":"28.7","Cell RNA - PC-3 [nTPM]":"20.0","Cell RNA - REH [nTPM]":"18.4","Cell RNA - RH-30 [nTPM]":"16.8","Cell RNA - RPMI-8226 [nTPM]":"29.4","Cell RNA - RPTEC TERT1 [nTPM]":"10.0","Cell RNA - RT4 [nTPM]":"26.5","Cell RNA - SCLC-21H [nTPM]":"17.0","Cell RNA - SH-SY5Y [nTPM]":"22.7","Cell RNA - SiHa [nTPM]":"13.3","Cell RNA - SK-BR-3 [nTPM]":"27.1","Cell RNA - SK-MEL-30 [nTPM]":"24.5","Cell RNA - SuSa [nTPM]":"4.2","Cell RNA - T-47d [nTPM]":"40.4","Cell RNA - THP-1 [nTPM]":"21.1","Cell RNA - TIME [nTPM]":"13.6","Cell RNA - U-138 MG [nTPM]":"14.8","Cell RNA - U-2 OS [nTPM]":"19.0","Cell RNA - U-2197 [nTPM]":"36.9","Cell RNA - U-251 MG [nTPM]":"21.5","Cell RNA - U-266\/70 [nTPM]":"47.1","Cell RNA - U-266\/84 [nTPM]":"33.1","Cell RNA - U-698 [nTPM]":"16.2","Cell RNA - U-87 MG [nTPM]":"16.2","Cell RNA - U-937 [nTPM]":"14.7","Cell RNA - WM-115 [nTPM]":"16.2","Blood RNA - basophil [nTPM]":"35.3","Blood RNA - classical monocyte [nTPM]":"44.1","Blood RNA - eosinophil [nTPM]":"36.8","Blood RNA - gdT-cell [nTPM]":"47.9","Blood RNA - intermediate monocyte [nTPM]":"51.0","Blood RNA - MAIT T-cell [nTPM]":"44.9","Blood RNA - memory B-cell [nTPM]":"57.0","Blood RNA - memory CD4 T-cell [nTPM]":"48.9","Blood RNA - memory CD8 T-cell [nTPM]":"49.6","Blood RNA - myeloid DC [nTPM]":"47.8","Blood RNA - naive B-cell [nTPM]":"50.5","Blood RNA - naive CD4 T-cell [nTPM]":"44.4","Blood RNA - naive CD8 T-cell [nTPM]":"46.7","Blood RNA - neutrophil [nTPM]":"32.2","Blood RNA - NK-cell [nTPM]":"44.9","Blood RNA - non-classical monocyte [nTPM]":"38.6","Blood RNA - plasmacytoid DC [nTPM]":"44.7","Blood RNA - T-reg [nTPM]":"61.1","Blood RNA - total PBMC [nTPM]":"46.1","Brain RNA - amygdala [nTPM]":"22.3","Brain RNA - basal ganglia [nTPM]":"23.8","Brain RNA - cerebellum [nTPM]":"23.4","Brain RNA - cerebral cortex [nTPM]":"24.4","Brain RNA - hippocampal formation [nTPM]":"23.0","Brain RNA - hypothalamus [nTPM]":"22.7","Brain RNA - medulla oblongata [nTPM]":"26.2","Brain RNA - midbrain [nTPM]":"23.6","Brain RNA - pons [nTPM]":"23.2","Brain RNA - spinal cord [nTPM]":"21.9","Brain RNA - thalamus [nTPM]":"23.6","Brain RNA - white matter [nTPM]":"26.0","Single Cell Type RNA - Adipocytes [nTPM]":"25.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.4","Single Cell Type RNA - Astrocytes [nTPM]":"3.9","Single Cell Type RNA - B-cells [nTPM]":"35.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"47.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.4","Single Cell Type RNA - Bipolar cells [nTPM]":"15.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"22.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"25.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"39.9","Single Cell Type RNA - dendritic cells [nTPM]":"31.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"45.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"50.9","Single Cell Type RNA - Ductal cells [nTPM]":"37.3","Single Cell Type RNA - Early spermatids [nTPM]":"25.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.8","Single Cell Type RNA - Endothelial cells [nTPM]":"21.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"28.1","Single Cell Type RNA - Erythroid cells [nTPM]":"25.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"88.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"22.2","Single Cell Type RNA - Fibroblasts [nTPM]":"15.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.3","Single Cell Type RNA - granulocytes [nTPM]":"21.0","Single Cell Type RNA - Granulosa cells [nTPM]":"16.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.8","Single Cell Type RNA - Hepatocytes [nTPM]":"68.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"34.2","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.5","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"37.7","Single Cell Type RNA - Langerhans cells [nTPM]":"19.7","Single Cell Type RNA - Late spermatids [nTPM]":"32.6","Single Cell Type RNA - Leydig cells [nTPM]":"19.3","Single Cell Type RNA - Macrophages [nTPM]":"20.0","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"46.6","Single Cell Type RNA - Muller glia cells [nTPM]":"28.8","Single Cell Type RNA - NK-cells [nTPM]":"26.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"55.9","Single Cell Type RNA - Paneth cells [nTPM]":"49.2","Single Cell Type RNA - Peritubular cells [nTPM]":"14.3","Single Cell Type RNA - Plasma cells [nTPM]":"27.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"26.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"90.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"68.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"26.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.0","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"24.4","Single Cell Type RNA - Spermatocytes [nTPM]":"27.2","Single Cell Type RNA - Spermatogonia [nTPM]":"15.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"64.0","Single Cell Type RNA - T-cells [nTPM]":"33.0","Single Cell Type RNA - Theca cells [nTPM]":"19.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"29.6","Single Cell Type RNA - Urothelial cells [nTPM]":"28.2"},{"Gene":"PEX19","Gene synonym":["D1S2223E","HK33","PMP1","PMPI","PXF","PXMP1"],"Ensembl":"ENSG00000162735","Gene description":"Peroxisomal biogenesis factor 19","Uniprot":["P40855"],"Chromosome":"1","Position":"160276807-160286348","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Peroxisome biogenesis"],"Molecular function":null,"Disease involvement":["Peroxisome biogenesis disorder","Zellweger syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044837","HPA051966"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Peroxisomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7900","Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":["Peroxisomes"],"Subcellular additional location":null,"Antibody RRID":{"HPA044837":"AB_10962496","HPA051966":"AB_2681677"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.92e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Tissue RNA - adipose tissue [nTPM]":"79.3","Tissue RNA - adrenal gland [nTPM]":"25.7","Tissue RNA - amygdala [nTPM]":"21.1","Tissue RNA - appendix [nTPM]":"14.5","Tissue RNA - basal ganglia [nTPM]":"22.5","Tissue RNA - bone marrow [nTPM]":"12.3","Tissue RNA - breast [nTPM]":"36.5","Tissue RNA - cerebellum [nTPM]":"22.2","Tissue RNA - cerebral cortex [nTPM]":"23.5","Tissue RNA - cervix [nTPM]":"20.3","Tissue RNA - choroid plexus [nTPM]":"15.6","Tissue RNA - colon [nTPM]":"22.6","Tissue RNA - duodenum [nTPM]":"19.4","Tissue RNA - endometrium 1 [nTPM]":"18.2","Tissue RNA - epididymis [nTPM]":"25.0","Tissue RNA - esophagus [nTPM]":"24.9","Tissue RNA - fallopian tube [nTPM]":"22.9","Tissue RNA - gallbladder [nTPM]":"19.6","Tissue RNA - heart muscle [nTPM]":"39.4","Tissue RNA - hippocampal formation [nTPM]":"21.5","Tissue RNA - hypothalamus [nTPM]":"22.7","Tissue RNA - kidney [nTPM]":"33.1","Tissue RNA - liver [nTPM]":"109.1","Tissue RNA - lung [nTPM]":"21.6","Tissue RNA - lymph node [nTPM]":"16.6","Tissue RNA - medulla oblongata [nTPM]":"22.3","Tissue RNA - midbrain [nTPM]":"23.5","Tissue RNA - ovary [nTPM]":"23.6","Tissue RNA - pancreas [nTPM]":"17.2","Tissue RNA - parathyroid gland [nTPM]":"40.4","Tissue RNA - pituitary gland [nTPM]":"15.0","Tissue RNA - placenta [nTPM]":"21.9","Tissue RNA - pons [nTPM]":"23.5","Tissue RNA - prostate [nTPM]":"28.0","Tissue RNA - rectum [nTPM]":"23.2","Tissue RNA - retina [nTPM]":"30.9","Tissue RNA - salivary gland [nTPM]":"21.3","Tissue RNA - seminal vesicle [nTPM]":"26.6","Tissue RNA - skeletal muscle [nTPM]":"66.2","Tissue RNA - skin 1 [nTPM]":"18.2","Tissue RNA - small intestine [nTPM]":"18.8","Tissue RNA - smooth muscle [nTPM]":"16.7","Tissue RNA - spinal cord [nTPM]":"22.1","Tissue RNA - spleen [nTPM]":"16.7","Tissue RNA - stomach 1 [nTPM]":"20.0","Tissue RNA - testis [nTPM]":"16.8","Tissue RNA - thalamus [nTPM]":"22.7","Tissue RNA - thymus [nTPM]":"21.0","Tissue RNA - thyroid gland [nTPM]":"34.3","Tissue RNA - tongue [nTPM]":"84.8","Tissue RNA - tonsil [nTPM]":"20.5","Tissue RNA - urinary bladder [nTPM]":"23.9","Tissue RNA - vagina [nTPM]":"15.2","Tissue RNA - white matter [nTPM]":"24.5","Cell RNA - A-431 [nTPM]":"31.2","Cell RNA - A549 [nTPM]":"18.9","Cell RNA - AF22 [nTPM]":"69.8","Cell RNA - AN3-CA [nTPM]":"22.4","Cell RNA - ASC diff [nTPM]":"59.8","Cell RNA - ASC TERT1 [nTPM]":"57.8","Cell RNA - BEWO [nTPM]":"53.0","Cell RNA - BJ [nTPM]":"25.3","Cell RNA - BJ hTERT+ [nTPM]":"51.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"44.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"35.3","Cell RNA - CACO-2 [nTPM]":"35.1","Cell RNA - CAPAN-2 [nTPM]":"37.2","Cell RNA - Daudi [nTPM]":"37.8","Cell RNA - EFO-21 [nTPM]":"40.9","Cell RNA - fHDF\/TERT166 [nTPM]":"37.3","Cell RNA - GAMG [nTPM]":"26.3","Cell RNA - HaCaT [nTPM]":"29.7","Cell RNA - HAP1 [nTPM]":"34.2","Cell RNA - HBEC3-KT [nTPM]":"44.0","Cell RNA - HBF TERT88 [nTPM]":"35.3","Cell RNA - HDLM-2 [nTPM]":"32.3","Cell RNA - HEK 293 [nTPM]":"17.3","Cell RNA - HEL [nTPM]":"26.6","Cell RNA - HeLa [nTPM]":"26.5","Cell RNA - Hep G2 [nTPM]":"36.3","Cell RNA - HHSteC [nTPM]":"46.9","Cell RNA - HL-60 [nTPM]":"48.6","Cell RNA - HMC-1 [nTPM]":"32.6","Cell RNA - HSkMC [nTPM]":"84.7","Cell RNA - hTCEpi [nTPM]":"51.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"60.0","Cell RNA - hTERT-HME1 [nTPM]":"38.6","Cell RNA - hTERT-RPE1 [nTPM]":"35.8","Cell RNA - HUVEC TERT2 [nTPM]":"32.2","Cell RNA - JURKAT [nTPM]":"51.4","Cell RNA - K-562 [nTPM]":"40.8","Cell RNA - Karpas-707 [nTPM]":"27.9","Cell RNA - LHCN-M2 [nTPM]":"50.0","Cell RNA - MCF7 [nTPM]":"17.8","Cell RNA - MOLT-4 [nTPM]":"37.0","Cell RNA - NB-4 [nTPM]":"15.8","Cell RNA - NTERA-2 [nTPM]":"50.3","Cell RNA - OE19 [nTPM]":"38.6","Cell RNA - PC-3 [nTPM]":"48.2","Cell RNA - REH [nTPM]":"45.7","Cell RNA - RH-30 [nTPM]":"34.4","Cell RNA - RPMI-8226 [nTPM]":"45.5","Cell RNA - RPTEC TERT1 [nTPM]":"45.8","Cell RNA - RT4 [nTPM]":"61.8","Cell RNA - SCLC-21H [nTPM]":"23.2","Cell RNA - SH-SY5Y [nTPM]":"38.3","Cell RNA - SiHa [nTPM]":"98.3","Cell RNA - SK-BR-3 [nTPM]":"49.5","Cell RNA - SK-MEL-30 [nTPM]":"37.4","Cell RNA - SuSa [nTPM]":"71.3","Cell RNA - T-47d [nTPM]":"48.1","Cell RNA - THP-1 [nTPM]":"48.2","Cell RNA - TIME [nTPM]":"24.8","Cell RNA - U-138 MG [nTPM]":"26.5","Cell RNA - U-2 OS [nTPM]":"31.1","Cell RNA - U-2197 [nTPM]":"29.9","Cell RNA - U-251 MG [nTPM]":"30.1","Cell RNA - U-266\/70 [nTPM]":"42.5","Cell RNA - U-266\/84 [nTPM]":"57.9","Cell RNA - U-698 [nTPM]":"68.6","Cell RNA - U-87 MG [nTPM]":"43.1","Cell RNA - U-937 [nTPM]":"20.9","Cell RNA - WM-115 [nTPM]":"38.9","Blood RNA - basophil [nTPM]":"9.1","Blood RNA - classical monocyte [nTPM]":"5.5","Blood RNA - eosinophil [nTPM]":"5.0","Blood RNA - gdT-cell [nTPM]":"5.8","Blood RNA - intermediate monocyte [nTPM]":"8.9","Blood RNA - MAIT T-cell [nTPM]":"4.2","Blood RNA - memory B-cell [nTPM]":"5.0","Blood RNA - memory CD4 T-cell [nTPM]":"2.8","Blood RNA - memory CD8 T-cell [nTPM]":"3.5","Blood RNA - myeloid DC [nTPM]":"5.5","Blood RNA - naive B-cell [nTPM]":"1.9","Blood RNA - naive CD4 T-cell [nTPM]":"4.0","Blood RNA - naive CD8 T-cell [nTPM]":"3.7","Blood RNA - neutrophil [nTPM]":"2.2","Blood RNA - NK-cell [nTPM]":"4.7","Blood RNA - non-classical monocyte [nTPM]":"6.6","Blood RNA - plasmacytoid DC [nTPM]":"3.4","Blood RNA - T-reg [nTPM]":"4.2","Blood RNA - total PBMC [nTPM]":"2.3","Brain RNA - amygdala [nTPM]":"21.1","Brain RNA - basal ganglia [nTPM]":"22.5","Brain RNA - cerebellum [nTPM]":"22.2","Brain RNA - cerebral cortex [nTPM]":"23.5","Brain RNA - hippocampal formation [nTPM]":"21.5","Brain RNA - hypothalamus [nTPM]":"22.7","Brain RNA - medulla oblongata [nTPM]":"22.3","Brain RNA - midbrain [nTPM]":"23.5","Brain RNA - pons [nTPM]":"23.5","Brain RNA - spinal cord [nTPM]":"22.1","Brain RNA - thalamus [nTPM]":"22.7","Brain RNA - white matter [nTPM]":"24.5","Single Cell Type RNA - Adipocytes [nTPM]":"16.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.6","Single Cell Type RNA - Astrocytes [nTPM]":"9.1","Single Cell Type RNA - B-cells [nTPM]":"12.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Bipolar cells [nTPM]":"18.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"45.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"11.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"30.0","Single Cell Type RNA - dendritic cells [nTPM]":"6.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"25.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"49.0","Single Cell Type RNA - Ductal cells [nTPM]":"22.6","Single Cell Type RNA - Early spermatids [nTPM]":"6.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.7","Single Cell Type RNA - Endothelial cells [nTPM]":"13.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.4","Single Cell Type RNA - Erythroid cells [nTPM]":"15.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"51.2","Single Cell Type RNA - Fibroblasts [nTPM]":"18.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.0","Single Cell Type RNA - granulocytes [nTPM]":"16.5","Single Cell Type RNA - Granulosa cells [nTPM]":"15.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.0","Single Cell Type RNA - Hepatocytes [nTPM]":"60.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.1","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"15.7","Single Cell Type RNA - Langerhans cells [nTPM]":"7.0","Single Cell Type RNA - Late spermatids [nTPM]":"3.1","Single Cell Type RNA - Leydig cells [nTPM]":"21.8","Single Cell Type RNA - Macrophages [nTPM]":"15.0","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"24.9","Single Cell Type RNA - Muller glia cells [nTPM]":"39.0","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.2","Single Cell Type RNA - Paneth cells [nTPM]":"17.2","Single Cell Type RNA - Peritubular cells [nTPM]":"29.3","Single Cell Type RNA - Plasma cells [nTPM]":"9.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"29.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"40.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.7","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.2","Single Cell Type RNA - Spermatocytes [nTPM]":"17.8","Single Cell Type RNA - Spermatogonia [nTPM]":"25.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"38.7","Single Cell Type RNA - T-cells [nTPM]":"12.5","Single Cell Type RNA - Theca cells [nTPM]":"18.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.7","Single Cell Type RNA - Urothelial cells [nTPM]":"25.2"},{"Gene":"PEX2","Gene synonym":["PAF-1","PMP35","PXMP3","RNF72","ZWS3"],"Ensembl":"ENSG00000164751","Gene description":"Peroxisomal biogenesis factor 2","Uniprot":["P28328"],"Chromosome":"8","Position":"76980258-77001044","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Peroxisome biogenesis"],"Molecular function":null,"Disease involvement":["Disease variant","Peroxisome biogenesis disorder","Zellweger syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"133.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010983","HPA011410","HPA027729"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA010983":null,"HPA011410":"AB_1854922","HPA027729":"AB_10610416"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.57e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Tissue RNA - adipose tissue [nTPM]":"39.8","Tissue RNA - adrenal gland [nTPM]":"45.9","Tissue RNA - amygdala [nTPM]":"33.1","Tissue RNA - appendix [nTPM]":"33.5","Tissue RNA - basal ganglia [nTPM]":"36.6","Tissue RNA - bone marrow [nTPM]":"35.8","Tissue RNA - breast [nTPM]":"53.9","Tissue RNA - cerebellum [nTPM]":"34.2","Tissue RNA - cerebral cortex [nTPM]":"45.6","Tissue RNA - cervix [nTPM]":"40.7","Tissue RNA - choroid plexus [nTPM]":"38.6","Tissue RNA - colon [nTPM]":"43.1","Tissue RNA - duodenum [nTPM]":"39.8","Tissue RNA - endometrium 1 [nTPM]":"33.3","Tissue RNA - epididymis [nTPM]":"42.4","Tissue RNA - esophagus [nTPM]":"32.9","Tissue RNA - fallopian tube [nTPM]":"41.8","Tissue RNA - gallbladder [nTPM]":"31.9","Tissue RNA - heart muscle [nTPM]":"39.7","Tissue RNA - hippocampal formation [nTPM]":"32.1","Tissue RNA - hypothalamus [nTPM]":"35.1","Tissue RNA - kidney [nTPM]":"53.6","Tissue RNA - liver [nTPM]":"43.7","Tissue RNA - lung [nTPM]":"36.5","Tissue RNA - lymph node [nTPM]":"39.4","Tissue RNA - medulla oblongata [nTPM]":"37.3","Tissue RNA - midbrain [nTPM]":"34.5","Tissue RNA - ovary [nTPM]":"33.3","Tissue RNA - pancreas [nTPM]":"39.0","Tissue RNA - parathyroid gland [nTPM]":"57.7","Tissue RNA - pituitary gland [nTPM]":"27.2","Tissue RNA - placenta [nTPM]":"24.7","Tissue RNA - pons [nTPM]":"37.6","Tissue RNA - prostate [nTPM]":"44.2","Tissue RNA - rectum [nTPM]":"39.6","Tissue RNA - retina [nTPM]":"66.5","Tissue RNA - salivary gland [nTPM]":"50.9","Tissue RNA - seminal vesicle [nTPM]":"83.4","Tissue RNA - skeletal muscle [nTPM]":"61.8","Tissue RNA - skin 1 [nTPM]":"24.5","Tissue RNA - small intestine [nTPM]":"41.0","Tissue RNA - smooth muscle [nTPM]":"35.3","Tissue RNA - spinal cord [nTPM]":"37.3","Tissue RNA - spleen [nTPM]":"36.5","Tissue RNA - stomach 1 [nTPM]":"48.3","Tissue RNA - testis [nTPM]":"22.1","Tissue RNA - thalamus [nTPM]":"34.5","Tissue RNA - thymus [nTPM]":"48.8","Tissue RNA - thyroid gland [nTPM]":"53.2","Tissue RNA - tongue [nTPM]":"44.6","Tissue RNA - tonsil [nTPM]":"35.7","Tissue RNA - urinary bladder [nTPM]":"35.7","Tissue RNA - vagina [nTPM]":"31.3","Tissue RNA - white matter [nTPM]":"43.3","Cell RNA - A-431 [nTPM]":"88.2","Cell RNA - A549 [nTPM]":"29.3","Cell RNA - AF22 [nTPM]":"46.9","Cell RNA - AN3-CA [nTPM]":"47.9","Cell RNA - ASC diff [nTPM]":"50.7","Cell RNA - ASC TERT1 [nTPM]":"63.2","Cell RNA - BEWO [nTPM]":"24.5","Cell RNA - BJ [nTPM]":"64.4","Cell RNA - BJ hTERT+ [nTPM]":"75.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"49.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"55.2","Cell RNA - CACO-2 [nTPM]":"18.4","Cell RNA - CAPAN-2 [nTPM]":"76.9","Cell RNA - Daudi [nTPM]":"50.2","Cell RNA - EFO-21 [nTPM]":"93.6","Cell RNA - fHDF\/TERT166 [nTPM]":"59.9","Cell RNA - GAMG [nTPM]":"39.7","Cell RNA - HaCaT [nTPM]":"33.3","Cell RNA - HAP1 [nTPM]":"33.1","Cell RNA - HBEC3-KT [nTPM]":"50.1","Cell RNA - HBF TERT88 [nTPM]":"61.2","Cell RNA - HDLM-2 [nTPM]":"93.3","Cell RNA - HEK 293 [nTPM]":"28.5","Cell RNA - HEL [nTPM]":"61.1","Cell RNA - HeLa [nTPM]":"26.0","Cell RNA - Hep G2 [nTPM]":"28.3","Cell RNA - HHSteC [nTPM]":"33.9","Cell RNA - HL-60 [nTPM]":"51.5","Cell RNA - HMC-1 [nTPM]":"46.5","Cell RNA - HSkMC [nTPM]":"70.9","Cell RNA - hTCEpi [nTPM]":"43.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"37.8","Cell RNA - hTERT-HME1 [nTPM]":"45.6","Cell RNA - hTERT-RPE1 [nTPM]":"77.0","Cell RNA - HUVEC TERT2 [nTPM]":"55.3","Cell RNA - JURKAT [nTPM]":"79.3","Cell RNA - K-562 [nTPM]":"34.4","Cell RNA - Karpas-707 [nTPM]":"46.7","Cell RNA - LHCN-M2 [nTPM]":"53.9","Cell RNA - MCF7 [nTPM]":"26.4","Cell RNA - MOLT-4 [nTPM]":"90.4","Cell RNA - NB-4 [nTPM]":"30.1","Cell RNA - NTERA-2 [nTPM]":"27.2","Cell RNA - OE19 [nTPM]":"126.4","Cell RNA - PC-3 [nTPM]":"26.3","Cell RNA - REH [nTPM]":"16.5","Cell RNA - RH-30 [nTPM]":"37.4","Cell RNA - RPMI-8226 [nTPM]":"42.1","Cell RNA - RPTEC TERT1 [nTPM]":"59.9","Cell RNA - RT4 [nTPM]":"61.6","Cell RNA - SCLC-21H [nTPM]":"16.7","Cell RNA - SH-SY5Y [nTPM]":"43.0","Cell RNA - SiHa [nTPM]":"41.9","Cell RNA - SK-BR-3 [nTPM]":"192.0","Cell RNA - SK-MEL-30 [nTPM]":"36.9","Cell RNA - SuSa [nTPM]":"39.8","Cell RNA - T-47d [nTPM]":"58.7","Cell RNA - THP-1 [nTPM]":"36.1","Cell RNA - TIME [nTPM]":"54.7","Cell RNA - U-138 MG [nTPM]":"44.4","Cell RNA - U-2 OS [nTPM]":"58.1","Cell RNA - U-2197 [nTPM]":"57.7","Cell RNA - U-251 MG [nTPM]":"32.4","Cell RNA - U-266\/70 [nTPM]":"86.0","Cell RNA - U-266\/84 [nTPM]":"53.8","Cell RNA - U-698 [nTPM]":"87.9","Cell RNA - U-87 MG [nTPM]":"56.5","Cell RNA - U-937 [nTPM]":"26.7","Cell RNA - WM-115 [nTPM]":"50.2","Blood RNA - basophil [nTPM]":"179.9","Blood RNA - classical monocyte [nTPM]":"55.6","Blood RNA - eosinophil [nTPM]":"102.6","Blood RNA - gdT-cell [nTPM]":"57.2","Blood RNA - intermediate monocyte [nTPM]":"58.0","Blood RNA - MAIT T-cell [nTPM]":"51.2","Blood RNA - memory B-cell [nTPM]":"46.1","Blood RNA - memory CD4 T-cell [nTPM]":"39.6","Blood RNA - memory CD8 T-cell [nTPM]":"46.5","Blood RNA - myeloid DC [nTPM]":"46.3","Blood RNA - naive B-cell [nTPM]":"50.5","Blood RNA - naive CD4 T-cell [nTPM]":"51.6","Blood RNA - naive CD8 T-cell [nTPM]":"49.3","Blood RNA - neutrophil [nTPM]":"38.6","Blood RNA - NK-cell [nTPM]":"83.1","Blood RNA - non-classical monocyte [nTPM]":"67.8","Blood RNA - plasmacytoid DC [nTPM]":"46.8","Blood RNA - T-reg [nTPM]":"48.6","Blood RNA - total PBMC [nTPM]":"71.7","Brain RNA - amygdala [nTPM]":"33.1","Brain RNA - basal ganglia [nTPM]":"36.6","Brain RNA - cerebellum [nTPM]":"34.2","Brain RNA - cerebral cortex [nTPM]":"45.6","Brain RNA - hippocampal formation [nTPM]":"32.1","Brain RNA - hypothalamus [nTPM]":"35.1","Brain RNA - medulla oblongata [nTPM]":"37.3","Brain RNA - midbrain [nTPM]":"34.5","Brain RNA - pons [nTPM]":"37.6","Brain RNA - spinal cord [nTPM]":"37.3","Brain RNA - thalamus [nTPM]":"34.5","Brain RNA - white matter [nTPM]":"43.3","Single Cell Type RNA - Adipocytes [nTPM]":"28.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.2","Single Cell Type RNA - Astrocytes [nTPM]":"32.3","Single Cell Type RNA - B-cells [nTPM]":"29.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"31.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"57.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"28.5","Single Cell Type RNA - Bipolar cells [nTPM]":"28.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"38.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"33.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"27.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"28.6","Single Cell Type RNA - Club cells [nTPM]":"38.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"42.8","Single Cell Type RNA - dendritic cells [nTPM]":"38.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"30.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"133.1","Single Cell Type RNA - Ductal cells [nTPM]":"52.3","Single Cell Type RNA - Early spermatids [nTPM]":"5.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"36.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.9","Single Cell Type RNA - Endothelial cells [nTPM]":"20.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"28.9","Single Cell Type RNA - Erythroid cells [nTPM]":"25.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"49.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"24.8","Single Cell Type RNA - Fibroblasts [nTPM]":"29.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"22.2","Single Cell Type RNA - granulocytes [nTPM]":"18.3","Single Cell Type RNA - Granulosa cells [nTPM]":"20.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.7","Single Cell Type RNA - Hepatocytes [nTPM]":"36.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"26.6","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"37.5","Single Cell Type RNA - Ionocytes [nTPM]":"48.8","Single Cell Type RNA - Kupffer cells [nTPM]":"39.1","Single Cell Type RNA - Langerhans cells [nTPM]":"22.4","Single Cell Type RNA - Late spermatids [nTPM]":"7.3","Single Cell Type RNA - Leydig cells [nTPM]":"29.5","Single Cell Type RNA - Macrophages [nTPM]":"26.8","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"36.3","Single Cell Type RNA - Muller glia cells [nTPM]":"68.4","Single Cell Type RNA - NK-cells [nTPM]":"53.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"31.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"45.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"42.0","Single Cell Type RNA - Paneth cells [nTPM]":"28.2","Single Cell Type RNA - Peritubular cells [nTPM]":"35.7","Single Cell Type RNA - Plasma cells [nTPM]":"41.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"36.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"43.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"61.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"36.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"34.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"34.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"24.6","Single Cell Type RNA - Spermatocytes [nTPM]":"13.7","Single Cell Type RNA - Spermatogonia [nTPM]":"20.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"34.8","Single Cell Type RNA - T-cells [nTPM]":"37.6","Single Cell Type RNA - Theca cells [nTPM]":"27.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"30.0","Single Cell Type RNA - Urothelial cells [nTPM]":"43.0"},{"Gene":"PEX26","Gene synonym":["FLJ20695"],"Ensembl":"ENSG00000215193","Gene description":"Peroxisomal biogenesis factor 26","Uniprot":["Q7Z412"],"Chromosome":"22","Position":"18077923-18105396","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Peroxisome biogenesis disorder","Zellweger syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"198.7","Proximal enterocytes":"91.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB070429"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB070429":"AB_11154363"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.75e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.92e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.10e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.38e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.5","Tissue RNA - adrenal gland [nTPM]":"5.8","Tissue RNA - amygdala [nTPM]":"7.3","Tissue RNA - appendix [nTPM]":"7.8","Tissue RNA - basal ganglia [nTPM]":"6.2","Tissue RNA - bone marrow [nTPM]":"12.1","Tissue RNA - breast [nTPM]":"6.7","Tissue RNA - cerebellum [nTPM]":"3.7","Tissue RNA - cerebral cortex [nTPM]":"6.8","Tissue RNA - cervix [nTPM]":"4.9","Tissue RNA - choroid plexus [nTPM]":"5.8","Tissue RNA - colon [nTPM]":"16.9","Tissue RNA - duodenum [nTPM]":"19.2","Tissue RNA - endometrium 1 [nTPM]":"5.5","Tissue RNA - epididymis [nTPM]":"5.3","Tissue RNA - esophagus [nTPM]":"7.5","Tissue RNA - fallopian tube [nTPM]":"6.0","Tissue RNA - gallbladder [nTPM]":"5.3","Tissue RNA - heart muscle [nTPM]":"5.8","Tissue RNA - hippocampal formation [nTPM]":"7.9","Tissue RNA - hypothalamus [nTPM]":"5.3","Tissue RNA - kidney [nTPM]":"7.5","Tissue RNA - liver [nTPM]":"7.3","Tissue RNA - lung [nTPM]":"5.0","Tissue RNA - lymph node [nTPM]":"7.3","Tissue RNA - medulla oblongata [nTPM]":"8.4","Tissue RNA - midbrain [nTPM]":"7.8","Tissue RNA - ovary [nTPM]":"5.4","Tissue RNA - pancreas [nTPM]":"8.0","Tissue RNA - parathyroid gland [nTPM]":"9.2","Tissue RNA - pituitary gland [nTPM]":"4.2","Tissue RNA - placenta [nTPM]":"5.0","Tissue RNA - pons [nTPM]":"7.0","Tissue RNA - prostate [nTPM]":"5.3","Tissue RNA - rectum [nTPM]":"13.1","Tissue RNA - retina [nTPM]":"3.1","Tissue RNA - salivary gland [nTPM]":"6.4","Tissue RNA - seminal vesicle [nTPM]":"5.6","Tissue RNA - skeletal muscle [nTPM]":"6.3","Tissue RNA - skin 1 [nTPM]":"5.6","Tissue RNA - small intestine [nTPM]":"19.9","Tissue RNA - smooth muscle [nTPM]":"5.4","Tissue RNA - spinal cord [nTPM]":"6.3","Tissue RNA - spleen [nTPM]":"8.1","Tissue RNA - stomach 1 [nTPM]":"9.3","Tissue RNA - testis [nTPM]":"3.1","Tissue RNA - thalamus [nTPM]":"8.3","Tissue RNA - thymus [nTPM]":"7.3","Tissue RNA - thyroid gland [nTPM]":"6.9","Tissue RNA - tongue [nTPM]":"4.1","Tissue RNA - tonsil [nTPM]":"6.7","Tissue RNA - urinary bladder [nTPM]":"6.0","Tissue RNA - vagina [nTPM]":"3.9","Tissue RNA - white matter [nTPM]":"5.5","Cell RNA - A-431 [nTPM]":"18.3","Cell RNA - A549 [nTPM]":"8.7","Cell RNA - AF22 [nTPM]":"10.2","Cell RNA - AN3-CA [nTPM]":"9.2","Cell RNA - ASC diff [nTPM]":"10.5","Cell RNA - ASC TERT1 [nTPM]":"6.6","Cell RNA - BEWO [nTPM]":"18.8","Cell RNA - BJ [nTPM]":"11.8","Cell RNA - BJ hTERT+ [nTPM]":"12.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.5","Cell RNA - CACO-2 [nTPM]":"15.2","Cell RNA - CAPAN-2 [nTPM]":"15.1","Cell RNA - Daudi [nTPM]":"11.3","Cell RNA - EFO-21 [nTPM]":"10.8","Cell RNA - fHDF\/TERT166 [nTPM]":"17.5","Cell RNA - GAMG [nTPM]":"11.2","Cell RNA - HaCaT [nTPM]":"18.7","Cell RNA - HAP1 [nTPM]":"15.9","Cell RNA - HBEC3-KT [nTPM]":"16.5","Cell RNA - HBF TERT88 [nTPM]":"10.9","Cell RNA - HDLM-2 [nTPM]":"19.0","Cell RNA - HEK 293 [nTPM]":"12.4","Cell RNA - HEL [nTPM]":"19.4","Cell RNA - HeLa [nTPM]":"12.3","Cell RNA - Hep G2 [nTPM]":"12.8","Cell RNA - HHSteC [nTPM]":"10.0","Cell RNA - HL-60 [nTPM]":"26.0","Cell RNA - HMC-1 [nTPM]":"23.6","Cell RNA - HSkMC [nTPM]":"8.2","Cell RNA - hTCEpi [nTPM]":"12.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"17.3","Cell RNA - hTERT-HME1 [nTPM]":"16.2","Cell RNA - hTERT-RPE1 [nTPM]":"6.1","Cell RNA - HUVEC TERT2 [nTPM]":"15.2","Cell RNA - JURKAT [nTPM]":"11.1","Cell RNA - K-562 [nTPM]":"21.2","Cell RNA - Karpas-707 [nTPM]":"8.1","Cell RNA - LHCN-M2 [nTPM]":"12.7","Cell RNA - MCF7 [nTPM]":"22.0","Cell RNA - MOLT-4 [nTPM]":"22.8","Cell RNA - NB-4 [nTPM]":"8.8","Cell RNA - NTERA-2 [nTPM]":"13.2","Cell RNA - OE19 [nTPM]":"24.9","Cell RNA - PC-3 [nTPM]":"15.7","Cell RNA - REH [nTPM]":"17.6","Cell RNA - RH-30 [nTPM]":"8.6","Cell RNA - RPMI-8226 [nTPM]":"4.1","Cell RNA - RPTEC TERT1 [nTPM]":"14.8","Cell RNA - RT4 [nTPM]":"20.6","Cell RNA - SCLC-21H [nTPM]":"17.7","Cell RNA - SH-SY5Y [nTPM]":"15.5","Cell RNA - SiHa [nTPM]":"17.1","Cell RNA - SK-BR-3 [nTPM]":"12.0","Cell RNA - SK-MEL-30 [nTPM]":"16.3","Cell RNA - SuSa [nTPM]":"8.2","Cell RNA - T-47d [nTPM]":"19.3","Cell RNA - THP-1 [nTPM]":"9.7","Cell RNA - TIME [nTPM]":"20.4","Cell RNA - U-138 MG [nTPM]":"23.6","Cell RNA - U-2 OS [nTPM]":"10.2","Cell RNA - U-2197 [nTPM]":"12.8","Cell RNA - U-251 MG [nTPM]":"12.4","Cell RNA - U-266\/70 [nTPM]":"21.4","Cell RNA - U-266\/84 [nTPM]":"15.8","Cell RNA - U-698 [nTPM]":"16.6","Cell RNA - U-87 MG [nTPM]":"10.9","Cell RNA - U-937 [nTPM]":"12.3","Cell RNA - WM-115 [nTPM]":"17.1","Blood RNA - basophil [nTPM]":"1.2","Blood RNA - classical monocyte [nTPM]":"1.7","Blood RNA - eosinophil [nTPM]":"1.4","Blood RNA - gdT-cell [nTPM]":"2.0","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"1.9","Blood RNA - memory B-cell [nTPM]":"1.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.8","Blood RNA - memory CD8 T-cell [nTPM]":"2.6","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"2.0","Blood RNA - naive CD4 T-cell [nTPM]":"2.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.3","Blood RNA - neutrophil [nTPM]":"1.2","Blood RNA - NK-cell [nTPM]":"2.7","Blood RNA - non-classical monocyte [nTPM]":"2.6","Blood RNA - plasmacytoid DC [nTPM]":"3.1","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"7.3","Brain RNA - basal ganglia [nTPM]":"6.2","Brain RNA - cerebellum [nTPM]":"3.7","Brain RNA - cerebral cortex [nTPM]":"6.8","Brain RNA - hippocampal formation [nTPM]":"7.9","Brain RNA - hypothalamus [nTPM]":"5.3","Brain RNA - medulla oblongata [nTPM]":"8.4","Brain RNA - midbrain [nTPM]":"7.8","Brain RNA - pons [nTPM]":"7.0","Brain RNA - spinal cord [nTPM]":"6.3","Brain RNA - thalamus [nTPM]":"8.3","Brain RNA - white matter [nTPM]":"5.5","Single Cell Type RNA - Adipocytes [nTPM]":"10.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.3","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"14.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"24.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"29.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"13.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"43.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.9","Single Cell Type RNA - dendritic cells [nTPM]":"18.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"198.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"24.7","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.2","Single Cell Type RNA - Endothelial cells [nTPM]":"17.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"24.5","Single Cell Type RNA - Erythroid cells [nTPM]":"11.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.8","Single Cell Type RNA - Fibroblasts [nTPM]":"13.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.6","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"19.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.9","Single Cell Type RNA - Hepatocytes [nTPM]":"33.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.2","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"22.9","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"20.4","Single Cell Type RNA - Langerhans cells [nTPM]":"10.7","Single Cell Type RNA - Late spermatids [nTPM]":"2.8","Single Cell Type RNA - Leydig cells [nTPM]":"12.5","Single Cell Type RNA - Macrophages [nTPM]":"11.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"20.4","Single Cell Type RNA - Muller glia cells [nTPM]":"9.2","Single Cell Type RNA - NK-cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"31.6","Single Cell Type RNA - Paneth cells [nTPM]":"51.8","Single Cell Type RNA - Peritubular cells [nTPM]":"11.7","Single Cell Type RNA - Plasma cells [nTPM]":"11.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"91.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"21.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"25.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.6","Single Cell Type RNA - Spermatocytes [nTPM]":"9.4","Single Cell Type RNA - Spermatogonia [nTPM]":"10.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.3","Single Cell Type RNA - T-cells [nTPM]":"13.9","Single Cell Type RNA - Theca cells [nTPM]":"21.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"29.4","Single Cell Type RNA - Urothelial cells [nTPM]":"18.7"},{"Gene":"PEX3","Gene synonym":[],"Ensembl":"ENSG00000034693","Gene description":"Peroxisomal biogenesis factor 3","Uniprot":["P56589"],"Chromosome":"6","Position":"143450805-143490616","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Peroxisome biogenesis"],"Molecular function":null,"Disease involvement":["Disease variant","Peroxisome biogenesis disorder","Zellweger syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"80.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042830","HPA058006"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Peroxisomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm","Peroxisomes"],"Subcellular additional location":null,"Antibody RRID":{"HPA042830":"AB_10794918","HPA058006":"AB_2683576"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.80e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Tissue RNA - adipose tissue [nTPM]":"8.7","Tissue RNA - adrenal gland [nTPM]":"38.4","Tissue RNA - amygdala [nTPM]":"4.4","Tissue RNA - appendix [nTPM]":"7.6","Tissue RNA - basal ganglia [nTPM]":"4.8","Tissue RNA - bone marrow [nTPM]":"3.2","Tissue RNA - breast [nTPM]":"11.8","Tissue RNA - cerebellum [nTPM]":"4.5","Tissue RNA - cerebral cortex [nTPM]":"5.6","Tissue RNA - cervix [nTPM]":"11.7","Tissue RNA - choroid plexus [nTPM]":"7.3","Tissue RNA - colon [nTPM]":"7.5","Tissue RNA - duodenum [nTPM]":"6.0","Tissue RNA - endometrium 1 [nTPM]":"9.8","Tissue RNA - epididymis [nTPM]":"12.5","Tissue RNA - esophagus [nTPM]":"17.8","Tissue RNA - fallopian tube [nTPM]":"9.6","Tissue RNA - gallbladder [nTPM]":"7.3","Tissue RNA - heart muscle [nTPM]":"12.6","Tissue RNA - hippocampal formation [nTPM]":"4.2","Tissue RNA - hypothalamus [nTPM]":"5.3","Tissue RNA - kidney [nTPM]":"18.3","Tissue RNA - liver [nTPM]":"24.4","Tissue RNA - lung [nTPM]":"7.9","Tissue RNA - lymph node [nTPM]":"8.8","Tissue RNA - medulla oblongata [nTPM]":"3.6","Tissue RNA - midbrain [nTPM]":"3.4","Tissue RNA - ovary [nTPM]":"10.7","Tissue RNA - pancreas [nTPM]":"6.7","Tissue RNA - parathyroid gland [nTPM]":"24.4","Tissue RNA - pituitary gland [nTPM]":"9.0","Tissue RNA - placenta [nTPM]":"9.4","Tissue RNA - pons [nTPM]":"3.9","Tissue RNA - prostate [nTPM]":"11.7","Tissue RNA - rectum [nTPM]":"6.2","Tissue RNA - retina [nTPM]":"10.0","Tissue RNA - salivary gland [nTPM]":"10.6","Tissue RNA - seminal vesicle [nTPM]":"11.2","Tissue RNA - skeletal muscle [nTPM]":"11.6","Tissue RNA - skin 1 [nTPM]":"12.8","Tissue RNA - small intestine [nTPM]":"7.4","Tissue RNA - smooth muscle [nTPM]":"8.9","Tissue RNA - spinal cord [nTPM]":"3.9","Tissue RNA - spleen [nTPM]":"7.2","Tissue RNA - stomach 1 [nTPM]":"9.7","Tissue RNA - testis [nTPM]":"12.2","Tissue RNA - thalamus [nTPM]":"3.6","Tissue RNA - thymus [nTPM]":"8.3","Tissue RNA - thyroid gland [nTPM]":"15.5","Tissue RNA - tongue [nTPM]":"9.6","Tissue RNA - tonsil [nTPM]":"9.5","Tissue RNA - urinary bladder [nTPM]":"8.9","Tissue RNA - vagina [nTPM]":"13.4","Tissue RNA - white matter [nTPM]":"7.5","Cell RNA - A-431 [nTPM]":"21.4","Cell RNA - A549 [nTPM]":"4.6","Cell RNA - AF22 [nTPM]":"11.0","Cell RNA - AN3-CA [nTPM]":"21.1","Cell RNA - ASC diff [nTPM]":"17.8","Cell RNA - ASC TERT1 [nTPM]":"15.6","Cell RNA - BEWO [nTPM]":"12.2","Cell RNA - BJ [nTPM]":"17.8","Cell RNA - BJ hTERT+ [nTPM]":"13.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"28.3","Cell RNA - CACO-2 [nTPM]":"31.5","Cell RNA - CAPAN-2 [nTPM]":"12.8","Cell RNA - Daudi [nTPM]":"31.7","Cell RNA - EFO-21 [nTPM]":"21.1","Cell RNA - fHDF\/TERT166 [nTPM]":"17.4","Cell RNA - GAMG [nTPM]":"27.8","Cell RNA - HaCaT [nTPM]":"17.3","Cell RNA - HAP1 [nTPM]":"14.4","Cell RNA - HBEC3-KT [nTPM]":"23.9","Cell RNA - HBF TERT88 [nTPM]":"30.8","Cell RNA - HDLM-2 [nTPM]":"19.4","Cell RNA - HEK 293 [nTPM]":"16.5","Cell RNA - HEL [nTPM]":"22.8","Cell RNA - HeLa [nTPM]":"10.2","Cell RNA - Hep G2 [nTPM]":"20.0","Cell RNA - HHSteC [nTPM]":"15.0","Cell RNA - HL-60 [nTPM]":"38.7","Cell RNA - HMC-1 [nTPM]":"9.6","Cell RNA - HSkMC [nTPM]":"18.1","Cell RNA - hTCEpi [nTPM]":"16.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.4","Cell RNA - hTERT-HME1 [nTPM]":"17.2","Cell RNA - hTERT-RPE1 [nTPM]":"10.3","Cell RNA - HUVEC TERT2 [nTPM]":"13.0","Cell RNA - JURKAT [nTPM]":"18.5","Cell RNA - K-562 [nTPM]":"21.1","Cell RNA - Karpas-707 [nTPM]":"15.7","Cell RNA - LHCN-M2 [nTPM]":"24.0","Cell RNA - MCF7 [nTPM]":"14.1","Cell RNA - MOLT-4 [nTPM]":"20.2","Cell RNA - NB-4 [nTPM]":"15.3","Cell RNA - NTERA-2 [nTPM]":"6.1","Cell RNA - OE19 [nTPM]":"12.6","Cell RNA - PC-3 [nTPM]":"18.2","Cell RNA - REH [nTPM]":"15.3","Cell RNA - RH-30 [nTPM]":"22.2","Cell RNA - RPMI-8226 [nTPM]":"14.0","Cell RNA - RPTEC TERT1 [nTPM]":"28.0","Cell RNA - RT4 [nTPM]":"9.2","Cell RNA - SCLC-21H [nTPM]":"15.3","Cell RNA - SH-SY5Y [nTPM]":"5.3","Cell RNA - SiHa [nTPM]":"23.0","Cell RNA - SK-BR-3 [nTPM]":"19.3","Cell RNA - SK-MEL-30 [nTPM]":"14.7","Cell RNA - SuSa [nTPM]":"9.5","Cell RNA - T-47d [nTPM]":"10.2","Cell RNA - THP-1 [nTPM]":"12.7","Cell RNA - TIME [nTPM]":"10.3","Cell RNA - U-138 MG [nTPM]":"16.7","Cell RNA - U-2 OS [nTPM]":"15.9","Cell RNA - U-2197 [nTPM]":"26.9","Cell RNA - U-251 MG [nTPM]":"20.9","Cell RNA - U-266\/70 [nTPM]":"10.7","Cell RNA - U-266\/84 [nTPM]":"16.4","Cell RNA - U-698 [nTPM]":"36.1","Cell RNA - U-87 MG [nTPM]":"21.1","Cell RNA - U-937 [nTPM]":"26.0","Cell RNA - WM-115 [nTPM]":"13.3","Blood RNA - basophil [nTPM]":"12.9","Blood RNA - classical monocyte [nTPM]":"6.3","Blood RNA - eosinophil [nTPM]":"6.4","Blood RNA - gdT-cell [nTPM]":"15.5","Blood RNA - intermediate monocyte [nTPM]":"10.1","Blood RNA - MAIT T-cell [nTPM]":"17.2","Blood RNA - memory B-cell [nTPM]":"23.2","Blood RNA - memory CD4 T-cell [nTPM]":"16.3","Blood RNA - memory CD8 T-cell [nTPM]":"15.5","Blood RNA - myeloid DC [nTPM]":"9.9","Blood RNA - naive B-cell [nTPM]":"18.6","Blood RNA - naive CD4 T-cell [nTPM]":"21.1","Blood RNA - naive CD8 T-cell [nTPM]":"20.7","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"15.6","Blood RNA - non-classical monocyte [nTPM]":"13.4","Blood RNA - plasmacytoid DC [nTPM]":"10.6","Blood RNA - T-reg [nTPM]":"21.2","Blood RNA - total PBMC [nTPM]":"9.8","Brain RNA - amygdala [nTPM]":"4.4","Brain RNA - basal ganglia [nTPM]":"4.8","Brain RNA - cerebellum [nTPM]":"4.5","Brain RNA - cerebral cortex [nTPM]":"5.6","Brain RNA - hippocampal formation [nTPM]":"4.2","Brain RNA - hypothalamus [nTPM]":"5.3","Brain RNA - medulla oblongata [nTPM]":"3.6","Brain RNA - midbrain [nTPM]":"3.4","Brain RNA - pons [nTPM]":"3.9","Brain RNA - spinal cord [nTPM]":"3.9","Brain RNA - thalamus [nTPM]":"3.6","Brain RNA - white matter [nTPM]":"7.5","Single Cell Type RNA - Adipocytes [nTPM]":"13.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.4","Single Cell Type RNA - Astrocytes [nTPM]":"23.8","Single Cell Type RNA - B-cells [nTPM]":"19.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"26.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"19.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"14.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"19.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"41.7","Single Cell Type RNA - dendritic cells [nTPM]":"9.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"12.3","Single Cell Type RNA - Early spermatids [nTPM]":"12.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.4","Single Cell Type RNA - Endothelial cells [nTPM]":"12.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"61.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.6","Single Cell Type RNA - Fibroblasts [nTPM]":"13.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.1","Single Cell Type RNA - granulocytes [nTPM]":"25.3","Single Cell Type RNA - Granulosa cells [nTPM]":"9.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"20.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.5","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"67.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.4","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"7.6","Single Cell Type RNA - Langerhans cells [nTPM]":"6.6","Single Cell Type RNA - Late spermatids [nTPM]":"4.9","Single Cell Type RNA - Leydig cells [nTPM]":"13.7","Single Cell Type RNA - Macrophages [nTPM]":"6.0","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"28.1","Single Cell Type RNA - monocytes [nTPM]":"8.0","Single Cell Type RNA - Muller glia cells [nTPM]":"15.4","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"40.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"59.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.6","Single Cell Type RNA - Paneth cells [nTPM]":"2.3","Single Cell Type RNA - Peritubular cells [nTPM]":"11.3","Single Cell Type RNA - Plasma cells [nTPM]":"18.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"28.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"27.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.6","Single Cell Type RNA - Spermatocytes [nTPM]":"80.0","Single Cell Type RNA - Spermatogonia [nTPM]":"18.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"34.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"58.7","Single Cell Type RNA - T-cells [nTPM]":"13.7","Single Cell Type RNA - Theca cells [nTPM]":"20.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.6","Single Cell Type RNA - Urothelial cells [nTPM]":"8.5"},{"Gene":"PEX6","Gene synonym":["PAF-2","PXAAA1"],"Ensembl":"ENSG00000124587","Gene description":"Peroxisomal biogenesis factor 6","Uniprot":["Q13608"],"Chromosome":"6","Position":"42963865-42979181","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Peroxisome biogenesis"],"Molecular function":null,"Disease involvement":["Amelogenesis imperfecta","Deafness","Disease variant","Peroxisome biogenesis disorder","Zellweger syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"76.2"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"OE19":"78.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA025924","HPA074179"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA025924":"AB_1855230","HPA074179":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.24e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Tissue RNA - adipose tissue [nTPM]":"11.6","Tissue RNA - adrenal gland [nTPM]":"20.5","Tissue RNA - amygdala [nTPM]":"24.9","Tissue RNA - appendix [nTPM]":"9.2","Tissue RNA - basal ganglia [nTPM]":"25.2","Tissue RNA - bone marrow [nTPM]":"9.5","Tissue RNA - breast [nTPM]":"12.1","Tissue RNA - cerebellum [nTPM]":"23.9","Tissue RNA - cerebral cortex [nTPM]":"27.7","Tissue RNA - cervix [nTPM]":"19.1","Tissue RNA - choroid plexus [nTPM]":"25.5","Tissue RNA - colon [nTPM]":"16.3","Tissue RNA - duodenum [nTPM]":"9.3","Tissue RNA - endometrium 1 [nTPM]":"15.5","Tissue RNA - epididymis [nTPM]":"7.7","Tissue RNA - esophagus [nTPM]":"16.4","Tissue RNA - fallopian tube [nTPM]":"22.7","Tissue RNA - gallbladder [nTPM]":"9.6","Tissue RNA - heart muscle [nTPM]":"18.7","Tissue RNA - hippocampal formation [nTPM]":"25.1","Tissue RNA - hypothalamus [nTPM]":"25.5","Tissue RNA - kidney [nTPM]":"16.5","Tissue RNA - liver [nTPM]":"27.7","Tissue RNA - lung [nTPM]":"10.0","Tissue RNA - lymph node [nTPM]":"14.5","Tissue RNA - medulla oblongata [nTPM]":"27.2","Tissue RNA - midbrain [nTPM]":"25.5","Tissue RNA - ovary [nTPM]":"26.1","Tissue RNA - pancreas [nTPM]":"76.2","Tissue RNA - parathyroid gland [nTPM]":"15.2","Tissue RNA - pituitary gland [nTPM]":"24.3","Tissue RNA - placenta [nTPM]":"9.6","Tissue RNA - pons [nTPM]":"24.2","Tissue RNA - prostate [nTPM]":"21.6","Tissue RNA - rectum [nTPM]":"7.8","Tissue RNA - retina [nTPM]":"9.9","Tissue RNA - salivary gland [nTPM]":"14.8","Tissue RNA - seminal vesicle [nTPM]":"11.4","Tissue RNA - skeletal muscle [nTPM]":"23.4","Tissue RNA - skin 1 [nTPM]":"14.0","Tissue RNA - small intestine [nTPM]":"16.3","Tissue RNA - smooth muscle [nTPM]":"9.6","Tissue RNA - spinal cord [nTPM]":"23.9","Tissue RNA - spleen [nTPM]":"17.5","Tissue RNA - stomach 1 [nTPM]":"16.3","Tissue RNA - testis [nTPM]":"16.2","Tissue RNA - thalamus [nTPM]":"25.1","Tissue RNA - thymus [nTPM]":"14.7","Tissue RNA - thyroid gland [nTPM]":"19.8","Tissue RNA - tongue [nTPM]":"15.0","Tissue RNA - tonsil [nTPM]":"10.4","Tissue RNA - urinary bladder [nTPM]":"17.3","Tissue RNA - vagina [nTPM]":"15.7","Tissue RNA - white matter [nTPM]":"25.2","Cell RNA - A-431 [nTPM]":"35.0","Cell RNA - A549 [nTPM]":"16.4","Cell RNA - AF22 [nTPM]":"8.1","Cell RNA - AN3-CA [nTPM]":"30.6","Cell RNA - ASC diff [nTPM]":"29.6","Cell RNA - ASC TERT1 [nTPM]":"28.3","Cell RNA - BEWO [nTPM]":"8.4","Cell RNA - BJ [nTPM]":"6.0","Cell RNA - BJ hTERT+ [nTPM]":"9.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.0","Cell RNA - CACO-2 [nTPM]":"10.5","Cell RNA - CAPAN-2 [nTPM]":"10.1","Cell RNA - Daudi [nTPM]":"14.1","Cell RNA - EFO-21 [nTPM]":"8.2","Cell RNA - fHDF\/TERT166 [nTPM]":"14.3","Cell RNA - GAMG [nTPM]":"20.5","Cell RNA - HaCaT [nTPM]":"32.2","Cell RNA - HAP1 [nTPM]":"28.7","Cell RNA - HBEC3-KT [nTPM]":"31.1","Cell RNA - HBF TERT88 [nTPM]":"5.0","Cell RNA - HDLM-2 [nTPM]":"27.6","Cell RNA - HEK 293 [nTPM]":"15.2","Cell RNA - HEL [nTPM]":"4.7","Cell RNA - HeLa [nTPM]":"24.4","Cell RNA - Hep G2 [nTPM]":"6.2","Cell RNA - HHSteC [nTPM]":"20.0","Cell RNA - HL-60 [nTPM]":"4.8","Cell RNA - HMC-1 [nTPM]":"9.4","Cell RNA - HSkMC [nTPM]":"35.5","Cell RNA - hTCEpi [nTPM]":"35.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.9","Cell RNA - hTERT-HME1 [nTPM]":"5.5","Cell RNA - hTERT-RPE1 [nTPM]":"39.1","Cell RNA - HUVEC TERT2 [nTPM]":"24.7","Cell RNA - JURKAT [nTPM]":"18.9","Cell RNA - K-562 [nTPM]":"25.2","Cell RNA - Karpas-707 [nTPM]":"14.1","Cell RNA - LHCN-M2 [nTPM]":"10.7","Cell RNA - MCF7 [nTPM]":"3.9","Cell RNA - MOLT-4 [nTPM]":"12.7","Cell RNA - NB-4 [nTPM]":"15.8","Cell RNA - NTERA-2 [nTPM]":"10.0","Cell RNA - OE19 [nTPM]":"78.8","Cell RNA - PC-3 [nTPM]":"14.3","Cell RNA - REH [nTPM]":"26.8","Cell RNA - RH-30 [nTPM]":"14.3","Cell RNA - RPMI-8226 [nTPM]":"5.8","Cell RNA - RPTEC TERT1 [nTPM]":"12.3","Cell RNA - RT4 [nTPM]":"10.0","Cell RNA - SCLC-21H [nTPM]":"25.4","Cell RNA - SH-SY5Y [nTPM]":"11.1","Cell RNA - SiHa [nTPM]":"5.6","Cell RNA - SK-BR-3 [nTPM]":"21.9","Cell RNA - SK-MEL-30 [nTPM]":"32.7","Cell RNA - SuSa [nTPM]":"13.1","Cell RNA - T-47d [nTPM]":"43.2","Cell RNA - THP-1 [nTPM]":"21.2","Cell RNA - TIME [nTPM]":"14.0","Cell RNA - U-138 MG [nTPM]":"15.2","Cell RNA - U-2 OS [nTPM]":"2.9","Cell RNA - U-2197 [nTPM]":"7.5","Cell RNA - U-251 MG [nTPM]":"14.0","Cell RNA - U-266\/70 [nTPM]":"21.0","Cell RNA - U-266\/84 [nTPM]":"19.8","Cell RNA - U-698 [nTPM]":"19.7","Cell RNA - U-87 MG [nTPM]":"5.2","Cell RNA - U-937 [nTPM]":"24.6","Cell RNA - WM-115 [nTPM]":"12.4","Blood RNA - basophil [nTPM]":"1.3","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"2.1","Blood RNA - gdT-cell [nTPM]":"1.2","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"2.1","Blood RNA - memory B-cell [nTPM]":"1.0","Blood RNA - memory CD4 T-cell [nTPM]":"1.8","Blood RNA - memory CD8 T-cell [nTPM]":"2.5","Blood RNA - myeloid DC [nTPM]":"1.9","Blood RNA - naive B-cell [nTPM]":"1.9","Blood RNA - naive CD4 T-cell [nTPM]":"2.2","Blood RNA - naive CD8 T-cell [nTPM]":"2.1","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"2.0","Blood RNA - non-classical monocyte [nTPM]":"0.7","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"0.9","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"24.9","Brain RNA - basal ganglia [nTPM]":"25.2","Brain RNA - cerebellum [nTPM]":"23.9","Brain RNA - cerebral cortex [nTPM]":"27.7","Brain RNA - hippocampal formation [nTPM]":"25.1","Brain RNA - hypothalamus [nTPM]":"25.5","Brain RNA - medulla oblongata [nTPM]":"27.2","Brain RNA - midbrain [nTPM]":"25.5","Brain RNA - pons [nTPM]":"24.2","Brain RNA - spinal cord [nTPM]":"23.9","Brain RNA - thalamus [nTPM]":"25.1","Brain RNA - white matter [nTPM]":"25.2","Single Cell Type RNA - Adipocytes [nTPM]":"5.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.6","Single Cell Type RNA - Astrocytes [nTPM]":"19.9","Single Cell Type RNA - B-cells [nTPM]":"5.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"15.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"5.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.4","Single Cell Type RNA - dendritic cells [nTPM]":"5.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"2.8","Single Cell Type RNA - Early spermatids [nTPM]":"2.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.6","Single Cell Type RNA - Endothelial cells [nTPM]":"5.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"24.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.7","Single Cell Type RNA - Fibroblasts [nTPM]":"9.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"19.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.6","Single Cell Type RNA - Hepatocytes [nTPM]":"14.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.8","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.5","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"9.7","Single Cell Type RNA - Langerhans cells [nTPM]":"3.2","Single Cell Type RNA - Late spermatids [nTPM]":"3.6","Single Cell Type RNA - Leydig cells [nTPM]":"14.6","Single Cell Type RNA - Macrophages [nTPM]":"5.4","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"4.5","Single Cell Type RNA - Muller glia cells [nTPM]":"11.8","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.9","Single Cell Type RNA - Paneth cells [nTPM]":"10.4","Single Cell Type RNA - Peritubular cells [nTPM]":"9.4","Single Cell Type RNA - Plasma cells [nTPM]":"3.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.6","Single Cell Type RNA - Spermatocytes [nTPM]":"7.3","Single Cell Type RNA - Spermatogonia [nTPM]":"2.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.4","Single Cell Type RNA - T-cells [nTPM]":"7.8","Single Cell Type RNA - Theca cells [nTPM]":"26.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.5","Single Cell Type RNA - Urothelial cells [nTPM]":"6.6"},{"Gene":"PEX7","Gene synonym":["PTS2R","RD"],"Ensembl":"ENSG00000112357","Gene description":"Peroxisomal biogenesis factor 7","Uniprot":["O00628"],"Chromosome":"6","Position":"136822564-136913934","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Cataract","Deafness","Disease variant","Ichthyosis","Peroxisome biogenesis disorder","Retinitis pigmentosa","Rhizomelic chondrodysplasia punctata"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"60.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049202"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA049202":"AB_2680674"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.61e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.85e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.2","Tissue RNA - adrenal gland [nTPM]":"14.8","Tissue RNA - amygdala [nTPM]":"4.6","Tissue RNA - appendix [nTPM]":"2.0","Tissue RNA - basal ganglia [nTPM]":"4.8","Tissue RNA - bone marrow [nTPM]":"3.8","Tissue RNA - breast [nTPM]":"11.9","Tissue RNA - cerebellum [nTPM]":"6.0","Tissue RNA - cerebral cortex [nTPM]":"5.2","Tissue RNA - cervix [nTPM]":"6.8","Tissue RNA - choroid plexus [nTPM]":"5.1","Tissue RNA - colon [nTPM]":"7.9","Tissue RNA - duodenum [nTPM]":"5.3","Tissue RNA - endometrium 1 [nTPM]":"4.2","Tissue RNA - epididymis [nTPM]":"17.2","Tissue RNA - esophagus [nTPM]":"7.3","Tissue RNA - fallopian tube [nTPM]":"8.7","Tissue RNA - gallbladder [nTPM]":"4.5","Tissue RNA - heart muscle [nTPM]":"11.7","Tissue RNA - hippocampal formation [nTPM]":"4.2","Tissue RNA - hypothalamus [nTPM]":"4.2","Tissue RNA - kidney [nTPM]":"15.6","Tissue RNA - liver [nTPM]":"9.1","Tissue RNA - lung [nTPM]":"4.9","Tissue RNA - lymph node [nTPM]":"3.2","Tissue RNA - medulla oblongata [nTPM]":"4.3","Tissue RNA - midbrain [nTPM]":"4.4","Tissue RNA - ovary [nTPM]":"5.0","Tissue RNA - pancreas [nTPM]":"26.9","Tissue RNA - parathyroid gland [nTPM]":"17.1","Tissue RNA - pituitary gland [nTPM]":"6.0","Tissue RNA - placenta [nTPM]":"4.1","Tissue RNA - pons [nTPM]":"4.5","Tissue RNA - prostate [nTPM]":"10.4","Tissue RNA - rectum [nTPM]":"8.4","Tissue RNA - retina [nTPM]":"6.9","Tissue RNA - salivary gland [nTPM]":"10.6","Tissue RNA - seminal vesicle [nTPM]":"6.4","Tissue RNA - skeletal muscle [nTPM]":"10.7","Tissue RNA - skin 1 [nTPM]":"11.2","Tissue RNA - small intestine [nTPM]":"4.7","Tissue RNA - smooth muscle [nTPM]":"3.3","Tissue RNA - spinal cord [nTPM]":"4.4","Tissue RNA - spleen [nTPM]":"3.3","Tissue RNA - stomach 1 [nTPM]":"15.6","Tissue RNA - testis [nTPM]":"10.0","Tissue RNA - thalamus [nTPM]":"4.7","Tissue RNA - thymus [nTPM]":"3.7","Tissue RNA - thyroid gland [nTPM]":"11.0","Tissue RNA - tongue [nTPM]":"9.8","Tissue RNA - tonsil [nTPM]":"3.3","Tissue RNA - urinary bladder [nTPM]":"5.4","Tissue RNA - vagina [nTPM]":"6.7","Tissue RNA - white matter [nTPM]":"5.5","Cell RNA - A-431 [nTPM]":"4.4","Cell RNA - A549 [nTPM]":"4.3","Cell RNA - AF22 [nTPM]":"4.4","Cell RNA - AN3-CA [nTPM]":"6.2","Cell RNA - ASC diff [nTPM]":"6.6","Cell RNA - ASC TERT1 [nTPM]":"9.8","Cell RNA - BEWO [nTPM]":"2.4","Cell RNA - BJ [nTPM]":"6.1","Cell RNA - BJ hTERT+ [nTPM]":"8.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.4","Cell RNA - CACO-2 [nTPM]":"4.9","Cell RNA - CAPAN-2 [nTPM]":"6.0","Cell RNA - Daudi [nTPM]":"1.5","Cell RNA - EFO-21 [nTPM]":"11.3","Cell RNA - fHDF\/TERT166 [nTPM]":"8.3","Cell RNA - GAMG [nTPM]":"8.5","Cell RNA - HaCaT [nTPM]":"5.3","Cell RNA - HAP1 [nTPM]":"3.3","Cell RNA - HBEC3-KT [nTPM]":"13.8","Cell RNA - HBF TERT88 [nTPM]":"9.8","Cell RNA - HDLM-2 [nTPM]":"5.7","Cell RNA - HEK 293 [nTPM]":"7.5","Cell RNA - HEL [nTPM]":"6.4","Cell RNA - HeLa [nTPM]":"4.3","Cell RNA - Hep G2 [nTPM]":"0.9","Cell RNA - HHSteC [nTPM]":"13.9","Cell RNA - HL-60 [nTPM]":"8.1","Cell RNA - HMC-1 [nTPM]":"5.3","Cell RNA - HSkMC [nTPM]":"9.6","Cell RNA - hTCEpi [nTPM]":"13.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.4","Cell RNA - hTERT-HME1 [nTPM]":"7.9","Cell RNA - hTERT-RPE1 [nTPM]":"8.7","Cell RNA - HUVEC TERT2 [nTPM]":"5.4","Cell RNA - JURKAT [nTPM]":"12.0","Cell RNA - K-562 [nTPM]":"13.0","Cell RNA - Karpas-707 [nTPM]":"5.2","Cell RNA - LHCN-M2 [nTPM]":"10.6","Cell RNA - MCF7 [nTPM]":"13.4","Cell RNA - MOLT-4 [nTPM]":"3.5","Cell RNA - NB-4 [nTPM]":"7.9","Cell RNA - NTERA-2 [nTPM]":"5.0","Cell RNA - OE19 [nTPM]":"13.9","Cell RNA - PC-3 [nTPM]":"8.3","Cell RNA - REH [nTPM]":"4.8","Cell RNA - RH-30 [nTPM]":"3.4","Cell RNA - RPMI-8226 [nTPM]":"5.7","Cell RNA - RPTEC TERT1 [nTPM]":"17.4","Cell RNA - RT4 [nTPM]":"6.4","Cell RNA - SCLC-21H [nTPM]":"8.3","Cell RNA - SH-SY5Y [nTPM]":"10.6","Cell RNA - SiHa [nTPM]":"6.5","Cell RNA - SK-BR-3 [nTPM]":"9.0","Cell RNA - SK-MEL-30 [nTPM]":"8.4","Cell RNA - SuSa [nTPM]":"4.9","Cell RNA - T-47d [nTPM]":"5.8","Cell RNA - THP-1 [nTPM]":"7.7","Cell RNA - TIME [nTPM]":"2.5","Cell RNA - U-138 MG [nTPM]":"4.8","Cell RNA - U-2 OS [nTPM]":"1.7","Cell RNA - U-2197 [nTPM]":"7.3","Cell RNA - U-251 MG [nTPM]":"5.3","Cell RNA - U-266\/70 [nTPM]":"6.9","Cell RNA - U-266\/84 [nTPM]":"5.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"4.2","Cell RNA - U-937 [nTPM]":"6.4","Cell RNA - WM-115 [nTPM]":"4.9","Blood RNA - basophil [nTPM]":"2.9","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"2.2","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"1.6","Blood RNA - myeloid DC [nTPM]":"2.3","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"2.4","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"1.6","Blood RNA - non-classical monocyte [nTPM]":"1.9","Blood RNA - plasmacytoid DC [nTPM]":"1.8","Blood RNA - T-reg [nTPM]":"2.3","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"4.6","Brain RNA - basal ganglia [nTPM]":"4.8","Brain RNA - cerebellum [nTPM]":"6.0","Brain RNA - cerebral cortex [nTPM]":"5.2","Brain RNA - hippocampal formation [nTPM]":"4.2","Brain RNA - hypothalamus [nTPM]":"4.2","Brain RNA - medulla oblongata [nTPM]":"4.3","Brain RNA - midbrain [nTPM]":"4.4","Brain RNA - pons [nTPM]":"4.5","Brain RNA - spinal cord [nTPM]":"4.4","Brain RNA - thalamus [nTPM]":"4.7","Brain RNA - white matter [nTPM]":"5.5","Single Cell Type RNA - Adipocytes [nTPM]":"4.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.4","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"6.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"9.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"14.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.6","Single Cell Type RNA - dendritic cells [nTPM]":"2.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"60.7","Single Cell Type RNA - Ductal cells [nTPM]":"16.5","Single Cell Type RNA - Early spermatids [nTPM]":"12.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.4","Single Cell Type RNA - Endothelial cells [nTPM]":"5.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.3","Single Cell Type RNA - Erythroid cells [nTPM]":"15.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"22.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.0","Single Cell Type RNA - Fibroblasts [nTPM]":"6.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.1","Single Cell Type RNA - granulocytes [nTPM]":"14.0","Single Cell Type RNA - Granulosa cells [nTPM]":"7.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"7.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.8","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"5.7","Single Cell Type RNA - Langerhans cells [nTPM]":"6.2","Single Cell Type RNA - Late spermatids [nTPM]":"10.2","Single Cell Type RNA - Leydig cells [nTPM]":"9.0","Single Cell Type RNA - Macrophages [nTPM]":"6.4","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"11.9","Single Cell Type RNA - Muller glia cells [nTPM]":"20.8","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.7","Single Cell Type RNA - Paneth cells [nTPM]":"13.2","Single Cell Type RNA - Peritubular cells [nTPM]":"9.8","Single Cell Type RNA - Plasma cells [nTPM]":"3.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"38.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.2","Single Cell Type RNA - Spermatocytes [nTPM]":"30.6","Single Cell Type RNA - Spermatogonia [nTPM]":"16.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.1","Single Cell Type RNA - T-cells [nTPM]":"6.6","Single Cell Type RNA - Theca cells [nTPM]":"24.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.2","Single Cell Type RNA - Urothelial cells [nTPM]":"17.4"},{"Gene":"PFKM","Gene synonym":["PFK-1","PFKX","PPP1R122"],"Ensembl":"ENSG00000152556","Gene description":"Phosphofructokinase, muscle","Uniprot":["P08237"],"Chromosome":"12","Position":"48105139-48146404","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Glycolysis"],"Molecular function":["Allosteric enzyme","Kinase","Transferase"],"Disease involvement":["Disease variant","Glycogen storage disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"skeletal muscle":"1570.1","tongue":"1393.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"345.9","Horizontal cells":"121.1","Muller glia cells":"125.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002117"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"410000","Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA002117":"AB_1855245"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.85e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.91e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.28e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Tissue RNA - adipose tissue [nTPM]":"18.7","Tissue RNA - adrenal gland [nTPM]":"54.2","Tissue RNA - amygdala [nTPM]":"50.4","Tissue RNA - appendix [nTPM]":"11.0","Tissue RNA - basal ganglia [nTPM]":"50.9","Tissue RNA - bone marrow [nTPM]":"8.0","Tissue RNA - breast [nTPM]":"15.0","Tissue RNA - cerebellum [nTPM]":"58.1","Tissue RNA - cerebral cortex [nTPM]":"59.3","Tissue RNA - cervix [nTPM]":"28.2","Tissue RNA - choroid plexus [nTPM]":"50.1","Tissue RNA - colon [nTPM]":"34.2","Tissue RNA - duodenum [nTPM]":"10.4","Tissue RNA - endometrium 1 [nTPM]":"36.1","Tissue RNA - epididymis [nTPM]":"14.3","Tissue RNA - esophagus [nTPM]":"38.6","Tissue RNA - fallopian tube [nTPM]":"29.2","Tissue RNA - gallbladder [nTPM]":"15.9","Tissue RNA - heart muscle [nTPM]":"298.6","Tissue RNA - hippocampal formation [nTPM]":"49.4","Tissue RNA - hypothalamus [nTPM]":"63.3","Tissue RNA - kidney [nTPM]":"46.0","Tissue RNA - liver [nTPM]":"8.4","Tissue RNA - lung [nTPM]":"14.9","Tissue RNA - lymph node [nTPM]":"8.0","Tissue RNA - medulla oblongata [nTPM]":"54.5","Tissue RNA - midbrain [nTPM]":"51.1","Tissue RNA - ovary [nTPM]":"45.1","Tissue RNA - pancreas [nTPM]":"10.9","Tissue RNA - parathyroid gland [nTPM]":"136.2","Tissue RNA - pituitary gland [nTPM]":"36.5","Tissue RNA - placenta [nTPM]":"12.0","Tissue RNA - pons [nTPM]":"58.7","Tissue RNA - prostate [nTPM]":"29.0","Tissue RNA - rectum [nTPM]":"16.1","Tissue RNA - retina [nTPM]":"85.5","Tissue RNA - salivary gland [nTPM]":"29.2","Tissue RNA - seminal vesicle [nTPM]":"39.0","Tissue RNA - skeletal muscle [nTPM]":"1570.1","Tissue RNA - skin 1 [nTPM]":"14.4","Tissue RNA - small intestine [nTPM]":"16.0","Tissue RNA - smooth muscle [nTPM]":"35.1","Tissue RNA - spinal cord [nTPM]":"46.1","Tissue RNA - spleen [nTPM]":"11.8","Tissue RNA - stomach 1 [nTPM]":"23.0","Tissue RNA - testis [nTPM]":"50.7","Tissue RNA - thalamus [nTPM]":"62.1","Tissue RNA - thymus [nTPM]":"9.3","Tissue RNA - thyroid gland [nTPM]":"21.5","Tissue RNA - tongue [nTPM]":"1393.9","Tissue RNA - tonsil [nTPM]":"10.2","Tissue RNA - urinary bladder [nTPM]":"27.7","Tissue RNA - vagina [nTPM]":"19.2","Tissue RNA - white matter [nTPM]":"43.4","Cell RNA - A-431 [nTPM]":"32.9","Cell RNA - A549 [nTPM]":"30.6","Cell RNA - AF22 [nTPM]":"98.4","Cell RNA - AN3-CA [nTPM]":"87.5","Cell RNA - ASC diff [nTPM]":"97.2","Cell RNA - ASC TERT1 [nTPM]":"72.5","Cell RNA - BEWO [nTPM]":"20.2","Cell RNA - BJ [nTPM]":"85.4","Cell RNA - BJ hTERT+ [nTPM]":"80.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"77.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"54.4","Cell RNA - CACO-2 [nTPM]":"76.3","Cell RNA - CAPAN-2 [nTPM]":"40.5","Cell RNA - Daudi [nTPM]":"192.9","Cell RNA - EFO-21 [nTPM]":"69.6","Cell RNA - fHDF\/TERT166 [nTPM]":"44.1","Cell RNA - GAMG [nTPM]":"44.9","Cell RNA - HaCaT [nTPM]":"36.0","Cell RNA - HAP1 [nTPM]":"90.1","Cell RNA - HBEC3-KT [nTPM]":"91.2","Cell RNA - HBF TERT88 [nTPM]":"70.9","Cell RNA - HDLM-2 [nTPM]":"5.5","Cell RNA - HEK 293 [nTPM]":"43.9","Cell RNA - HEL [nTPM]":"54.7","Cell RNA - HeLa [nTPM]":"64.7","Cell RNA - Hep G2 [nTPM]":"1.9","Cell RNA - HHSteC [nTPM]":"54.3","Cell RNA - HL-60 [nTPM]":"2.9","Cell RNA - HMC-1 [nTPM]":"30.9","Cell RNA - HSkMC [nTPM]":"102.1","Cell RNA - hTCEpi [nTPM]":"50.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"69.2","Cell RNA - hTERT-HME1 [nTPM]":"107.3","Cell RNA - hTERT-RPE1 [nTPM]":"125.1","Cell RNA - HUVEC TERT2 [nTPM]":"85.9","Cell RNA - JURKAT [nTPM]":"3.7","Cell RNA - K-562 [nTPM]":"64.6","Cell RNA - Karpas-707 [nTPM]":"91.7","Cell RNA - LHCN-M2 [nTPM]":"71.5","Cell RNA - MCF7 [nTPM]":"25.8","Cell RNA - MOLT-4 [nTPM]":"69.5","Cell RNA - NB-4 [nTPM]":"5.1","Cell RNA - NTERA-2 [nTPM]":"67.7","Cell RNA - OE19 [nTPM]":"36.0","Cell RNA - PC-3 [nTPM]":"93.9","Cell RNA - REH [nTPM]":"115.7","Cell RNA - RH-30 [nTPM]":"55.7","Cell RNA - RPMI-8226 [nTPM]":"141.3","Cell RNA - RPTEC TERT1 [nTPM]":"48.4","Cell RNA - RT4 [nTPM]":"32.5","Cell RNA - SCLC-21H [nTPM]":"111.5","Cell RNA - SH-SY5Y [nTPM]":"82.6","Cell RNA - SiHa [nTPM]":"51.0","Cell RNA - SK-BR-3 [nTPM]":"75.9","Cell RNA - SK-MEL-30 [nTPM]":"86.5","Cell RNA - SuSa [nTPM]":"78.7","Cell RNA - T-47d [nTPM]":"80.3","Cell RNA - THP-1 [nTPM]":"11.2","Cell RNA - TIME [nTPM]":"75.8","Cell RNA - U-138 MG [nTPM]":"34.0","Cell RNA - U-2 OS [nTPM]":"46.5","Cell RNA - U-2197 [nTPM]":"49.5","Cell RNA - U-251 MG [nTPM]":"72.1","Cell RNA - U-266\/70 [nTPM]":"52.8","Cell RNA - U-266\/84 [nTPM]":"145.3","Cell RNA - U-698 [nTPM]":"106.4","Cell RNA - U-87 MG [nTPM]":"62.4","Cell RNA - U-937 [nTPM]":"6.8","Cell RNA - WM-115 [nTPM]":"28.5","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"2.9","Blood RNA - eosinophil [nTPM]":"7.8","Blood RNA - gdT-cell [nTPM]":"2.1","Blood RNA - intermediate monocyte [nTPM]":"2.5","Blood RNA - MAIT T-cell [nTPM]":"0.9","Blood RNA - memory B-cell [nTPM]":"8.8","Blood RNA - memory CD4 T-cell [nTPM]":"3.5","Blood RNA - memory CD8 T-cell [nTPM]":"2.1","Blood RNA - myeloid DC [nTPM]":"5.6","Blood RNA - naive B-cell [nTPM]":"8.3","Blood RNA - naive CD4 T-cell [nTPM]":"4.3","Blood RNA - naive CD8 T-cell [nTPM]":"2.4","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"2.1","Blood RNA - non-classical monocyte [nTPM]":"2.1","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"3.5","Blood RNA - total PBMC [nTPM]":"3.1","Brain RNA - amygdala [nTPM]":"50.4","Brain RNA - basal ganglia [nTPM]":"50.9","Brain RNA - cerebellum [nTPM]":"58.1","Brain RNA - cerebral cortex [nTPM]":"59.3","Brain RNA - hippocampal formation [nTPM]":"49.4","Brain RNA - hypothalamus [nTPM]":"63.3","Brain RNA - medulla oblongata [nTPM]":"54.5","Brain RNA - midbrain [nTPM]":"51.1","Brain RNA - pons [nTPM]":"58.7","Brain RNA - spinal cord [nTPM]":"46.1","Brain RNA - thalamus [nTPM]":"62.1","Brain RNA - white matter [nTPM]":"43.4","Single Cell Type RNA - Adipocytes [nTPM]":"8.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.4","Single Cell Type RNA - Astrocytes [nTPM]":"30.3","Single Cell Type RNA - B-cells [nTPM]":"6.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Bipolar cells [nTPM]":"43.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"345.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"10.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"43.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.8","Single Cell Type RNA - dendritic cells [nTPM]":"0.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"66.5","Single Cell Type RNA - Ductal cells [nTPM]":"10.6","Single Cell Type RNA - Early spermatids [nTPM]":"43.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.0","Single Cell Type RNA - Endothelial cells [nTPM]":"17.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.1","Single Cell Type RNA - Erythroid cells [nTPM]":"8.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.8","Single Cell Type RNA - Fibroblasts [nTPM]":"27.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.4","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"17.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.9","Single Cell Type RNA - Hepatocytes [nTPM]":"2.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.1","Single Cell Type RNA - Horizontal cells [nTPM]":"121.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"30.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.1","Single Cell Type RNA - Ionocytes [nTPM]":"34.6","Single Cell Type RNA - Kupffer cells [nTPM]":"3.8","Single Cell Type RNA - Langerhans cells [nTPM]":"3.7","Single Cell Type RNA - Late spermatids [nTPM]":"27.0","Single Cell Type RNA - Leydig cells [nTPM]":"30.7","Single Cell Type RNA - Macrophages [nTPM]":"4.3","Single Cell Type RNA - Melanocytes [nTPM]":"55.2","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"11.3","Single Cell Type RNA - Muller glia cells [nTPM]":"125.7","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.5","Single Cell Type RNA - Paneth cells [nTPM]":"1.9","Single Cell Type RNA - Peritubular cells [nTPM]":"47.8","Single Cell Type RNA - Plasma cells [nTPM]":"4.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"30.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"51.1","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"37.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"24.5","Single Cell Type RNA - Spermatocytes [nTPM]":"52.1","Single Cell Type RNA - Spermatogonia [nTPM]":"14.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - T-cells [nTPM]":"3.3","Single Cell Type RNA - Theca cells [nTPM]":"24.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.1","Single Cell Type RNA - Urothelial cells [nTPM]":"9.7"},{"Gene":"PGAM2","Gene synonym":["PGAM-M"],"Ensembl":"ENSG00000164708","Gene description":"Phosphoglycerate mutase 2","Uniprot":["P15259"],"Chromosome":"7","Position":"44062727-44065567","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Glycolysis"],"Molecular function":["Hydrolase","Isomerase"],"Disease involvement":["Disease variant","Glycogen storage disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"heart muscle":"1132.9","skeletal muscle":"4350.5","tongue":"1754.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Early spermatids":"539.1","Late spermatids":"1891.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"SCLC-21H":"65.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043801","HPA050314","HPA060173"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"38000000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli","Cytosol"],"Antibody RRID":{"HPA043801":null,"HPA050314":"AB_2732558","HPA060173":"AB_2684215"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"4.1","Tissue RNA - adrenal gland [nTPM]":"3.7","Tissue RNA - amygdala [nTPM]":"32.9","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"37.7","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"2.9","Tissue RNA - cerebellum [nTPM]":"40.9","Tissue RNA - cerebral cortex [nTPM]":"43.1","Tissue RNA - cervix [nTPM]":"2.8","Tissue RNA - choroid plexus [nTPM]":"28.9","Tissue RNA - colon [nTPM]":"2.1","Tissue RNA - duodenum [nTPM]":"2.0","Tissue RNA - endometrium 1 [nTPM]":"1.8","Tissue RNA - epididymis [nTPM]":"0.7","Tissue RNA - esophagus [nTPM]":"58.9","Tissue RNA - fallopian tube [nTPM]":"2.3","Tissue RNA - gallbladder [nTPM]":"2.4","Tissue RNA - heart muscle [nTPM]":"1132.9","Tissue RNA - hippocampal formation [nTPM]":"29.3","Tissue RNA - hypothalamus [nTPM]":"45.0","Tissue RNA - kidney [nTPM]":"10.6","Tissue RNA - liver [nTPM]":"1.8","Tissue RNA - lung [nTPM]":"2.0","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"33.8","Tissue RNA - midbrain [nTPM]":"39.8","Tissue RNA - ovary [nTPM]":"2.0","Tissue RNA - pancreas [nTPM]":"2.1","Tissue RNA - parathyroid gland [nTPM]":"4.0","Tissue RNA - pituitary gland [nTPM]":"13.5","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"46.0","Tissue RNA - prostate [nTPM]":"16.5","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"4.3","Tissue RNA - salivary gland [nTPM]":"33.6","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"4350.5","Tissue RNA - skin 1 [nTPM]":"1.8","Tissue RNA - small intestine [nTPM]":"1.3","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"30.8","Tissue RNA - spleen [nTPM]":"1.2","Tissue RNA - stomach 1 [nTPM]":"1.7","Tissue RNA - testis [nTPM]":"193.9","Tissue RNA - thalamus [nTPM]":"46.8","Tissue RNA - thymus [nTPM]":"23.9","Tissue RNA - thyroid gland [nTPM]":"5.1","Tissue RNA - tongue [nTPM]":"1754.5","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"0.7","Tissue RNA - vagina [nTPM]":"1.9","Tissue RNA - white matter [nTPM]":"39.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.9","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"65.8","Cell RNA - SH-SY5Y [nTPM]":"7.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.7","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"1.0","Cell RNA - U-266\/84 [nTPM]":"0.7","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"32.9","Brain RNA - basal ganglia [nTPM]":"37.7","Brain RNA - cerebellum [nTPM]":"40.9","Brain RNA - cerebral cortex [nTPM]":"43.1","Brain RNA - hippocampal formation [nTPM]":"29.3","Brain RNA - hypothalamus [nTPM]":"45.0","Brain RNA - medulla oblongata [nTPM]":"33.8","Brain RNA - midbrain [nTPM]":"39.8","Brain RNA - pons [nTPM]":"46.0","Brain RNA - spinal cord [nTPM]":"30.8","Brain RNA - thalamus [nTPM]":"46.8","Brain RNA - white matter [nTPM]":"39.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"1.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"15.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"80.3","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"539.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"1.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.9","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1.4","Single Cell Type RNA - Late spermatids [nTPM]":"1891.7","Single Cell Type RNA - Leydig cells [nTPM]":"7.8","Single Cell Type RNA - Macrophages [nTPM]":"1.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"5.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.6","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"78.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.6","Single Cell Type RNA - Spermatocytes [nTPM]":"187.6","Single Cell Type RNA - Spermatogonia [nTPM]":"7.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.5"},{"Gene":"PGAP2","Gene synonym":["CWH43-N","FRAG1","MRT17","MRT21"],"Ensembl":"ENSG00000148985","Gene description":"Post-GPI attachment to proteins 2","Uniprot":["Q9UHJ9"],"Chromosome":"11","Position":"3797724-3826371","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["GPI-anchor biosynthesis"],"Molecular function":null,"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"epididymis":"216.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cytotrophoblasts":"74.9","Early spermatids":"147.6","Late spermatids":"296.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063099"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 30: Epididymis - Antimicrobial activity","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA063099":"AB_2684940"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.49e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.9","Tissue RNA - adrenal gland [nTPM]":"14.9","Tissue RNA - amygdala [nTPM]":"16.4","Tissue RNA - appendix [nTPM]":"6.4","Tissue RNA - basal ganglia [nTPM]":"17.5","Tissue RNA - bone marrow [nTPM]":"9.5","Tissue RNA - breast [nTPM]":"11.5","Tissue RNA - cerebellum [nTPM]":"15.9","Tissue RNA - cerebral cortex [nTPM]":"18.2","Tissue RNA - cervix [nTPM]":"13.7","Tissue RNA - choroid plexus [nTPM]":"17.0","Tissue RNA - colon [nTPM]":"13.9","Tissue RNA - duodenum [nTPM]":"18.4","Tissue RNA - endometrium 1 [nTPM]":"8.3","Tissue RNA - epididymis [nTPM]":"216.2","Tissue RNA - esophagus [nTPM]":"34.9","Tissue RNA - fallopian tube [nTPM]":"19.2","Tissue RNA - gallbladder [nTPM]":"7.6","Tissue RNA - heart muscle [nTPM]":"21.7","Tissue RNA - hippocampal formation [nTPM]":"16.6","Tissue RNA - hypothalamus [nTPM]":"16.3","Tissue RNA - kidney [nTPM]":"13.9","Tissue RNA - liver [nTPM]":"30.9","Tissue RNA - lung [nTPM]":"16.2","Tissue RNA - lymph node [nTPM]":"10.4","Tissue RNA - medulla oblongata [nTPM]":"17.8","Tissue RNA - midbrain [nTPM]":"16.6","Tissue RNA - ovary [nTPM]":"11.2","Tissue RNA - pancreas [nTPM]":"28.9","Tissue RNA - parathyroid gland [nTPM]":"17.6","Tissue RNA - pituitary gland [nTPM]":"15.1","Tissue RNA - placenta [nTPM]":"14.2","Tissue RNA - pons [nTPM]":"17.2","Tissue RNA - prostate [nTPM]":"16.7","Tissue RNA - rectum [nTPM]":"13.3","Tissue RNA - retina [nTPM]":"9.2","Tissue RNA - salivary gland [nTPM]":"18.4","Tissue RNA - seminal vesicle [nTPM]":"33.4","Tissue RNA - skeletal muscle [nTPM]":"11.4","Tissue RNA - skin 1 [nTPM]":"48.0","Tissue RNA - small intestine [nTPM]":"16.0","Tissue RNA - smooth muscle [nTPM]":"7.6","Tissue RNA - spinal cord [nTPM]":"16.3","Tissue RNA - spleen [nTPM]":"11.3","Tissue RNA - stomach 1 [nTPM]":"14.1","Tissue RNA - testis [nTPM]":"28.5","Tissue RNA - thalamus [nTPM]":"17.3","Tissue RNA - thymus [nTPM]":"13.1","Tissue RNA - thyroid gland [nTPM]":"19.4","Tissue RNA - tongue [nTPM]":"9.5","Tissue RNA - tonsil [nTPM]":"13.5","Tissue RNA - urinary bladder [nTPM]":"10.9","Tissue RNA - vagina [nTPM]":"18.8","Tissue RNA - white matter [nTPM]":"20.9","Cell RNA - A-431 [nTPM]":"27.1","Cell RNA - A549 [nTPM]":"36.3","Cell RNA - AF22 [nTPM]":"17.2","Cell RNA - AN3-CA [nTPM]":"15.8","Cell RNA - ASC diff [nTPM]":"15.2","Cell RNA - ASC TERT1 [nTPM]":"28.9","Cell RNA - BEWO [nTPM]":"27.3","Cell RNA - BJ [nTPM]":"10.9","Cell RNA - BJ hTERT+ [nTPM]":"9.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.2","Cell RNA - CACO-2 [nTPM]":"31.1","Cell RNA - CAPAN-2 [nTPM]":"46.6","Cell RNA - Daudi [nTPM]":"29.0","Cell RNA - EFO-21 [nTPM]":"12.3","Cell RNA - fHDF\/TERT166 [nTPM]":"8.0","Cell RNA - GAMG [nTPM]":"9.4","Cell RNA - HaCaT [nTPM]":"44.1","Cell RNA - HAP1 [nTPM]":"27.6","Cell RNA - HBEC3-KT [nTPM]":"30.2","Cell RNA - HBF TERT88 [nTPM]":"15.5","Cell RNA - HDLM-2 [nTPM]":"35.5","Cell RNA - HEK 293 [nTPM]":"30.9","Cell RNA - HEL [nTPM]":"17.7","Cell RNA - HeLa [nTPM]":"14.7","Cell RNA - Hep G2 [nTPM]":"38.4","Cell RNA - HHSteC [nTPM]":"10.7","Cell RNA - HL-60 [nTPM]":"23.0","Cell RNA - HMC-1 [nTPM]":"22.0","Cell RNA - HSkMC [nTPM]":"22.8","Cell RNA - hTCEpi [nTPM]":"41.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.6","Cell RNA - hTERT-HME1 [nTPM]":"39.3","Cell RNA - hTERT-RPE1 [nTPM]":"10.2","Cell RNA - HUVEC TERT2 [nTPM]":"18.0","Cell RNA - JURKAT [nTPM]":"38.4","Cell RNA - K-562 [nTPM]":"38.4","Cell RNA - Karpas-707 [nTPM]":"41.8","Cell RNA - LHCN-M2 [nTPM]":"16.6","Cell RNA - MCF7 [nTPM]":"39.9","Cell RNA - MOLT-4 [nTPM]":"28.0","Cell RNA - NB-4 [nTPM]":"19.3","Cell RNA - NTERA-2 [nTPM]":"32.4","Cell RNA - OE19 [nTPM]":"56.7","Cell RNA - PC-3 [nTPM]":"21.5","Cell RNA - REH [nTPM]":"44.0","Cell RNA - RH-30 [nTPM]":"2.0","Cell RNA - RPMI-8226 [nTPM]":"27.8","Cell RNA - RPTEC TERT1 [nTPM]":"30.0","Cell RNA - RT4 [nTPM]":"31.6","Cell RNA - SCLC-21H [nTPM]":"22.7","Cell RNA - SH-SY5Y [nTPM]":"22.5","Cell RNA - SiHa [nTPM]":"19.7","Cell RNA - SK-BR-3 [nTPM]":"52.0","Cell RNA - SK-MEL-30 [nTPM]":"12.3","Cell RNA - SuSa [nTPM]":"20.1","Cell RNA - T-47d [nTPM]":"43.2","Cell RNA - THP-1 [nTPM]":"9.6","Cell RNA - TIME [nTPM]":"16.5","Cell RNA - U-138 MG [nTPM]":"9.9","Cell RNA - U-2 OS [nTPM]":"9.2","Cell RNA - U-2197 [nTPM]":"23.8","Cell RNA - U-251 MG [nTPM]":"6.8","Cell RNA - U-266\/70 [nTPM]":"26.2","Cell RNA - U-266\/84 [nTPM]":"31.3","Cell RNA - U-698 [nTPM]":"21.6","Cell RNA - U-87 MG [nTPM]":"12.9","Cell RNA - U-937 [nTPM]":"15.3","Cell RNA - WM-115 [nTPM]":"19.1","Blood RNA - basophil [nTPM]":"3.0","Blood RNA - classical monocyte [nTPM]":"6.4","Blood RNA - eosinophil [nTPM]":"5.9","Blood RNA - gdT-cell [nTPM]":"9.1","Blood RNA - intermediate monocyte [nTPM]":"9.2","Blood RNA - MAIT T-cell [nTPM]":"11.0","Blood RNA - memory B-cell [nTPM]":"11.4","Blood RNA - memory CD4 T-cell [nTPM]":"13.2","Blood RNA - memory CD8 T-cell [nTPM]":"11.3","Blood RNA - myeloid DC [nTPM]":"9.7","Blood RNA - naive B-cell [nTPM]":"12.7","Blood RNA - naive CD4 T-cell [nTPM]":"17.3","Blood RNA - naive CD8 T-cell [nTPM]":"11.8","Blood RNA - neutrophil [nTPM]":"18.2","Blood RNA - NK-cell [nTPM]":"10.7","Blood RNA - non-classical monocyte [nTPM]":"9.2","Blood RNA - plasmacytoid DC [nTPM]":"6.6","Blood RNA - T-reg [nTPM]":"13.3","Blood RNA - total PBMC [nTPM]":"8.8","Brain RNA - amygdala [nTPM]":"16.4","Brain RNA - basal ganglia [nTPM]":"17.5","Brain RNA - cerebellum [nTPM]":"15.9","Brain RNA - cerebral cortex [nTPM]":"18.2","Brain RNA - hippocampal formation [nTPM]":"16.6","Brain RNA - hypothalamus [nTPM]":"16.3","Brain RNA - medulla oblongata [nTPM]":"17.8","Brain RNA - midbrain [nTPM]":"16.6","Brain RNA - pons [nTPM]":"17.2","Brain RNA - spinal cord [nTPM]":"16.3","Brain RNA - thalamus [nTPM]":"17.3","Brain RNA - white matter [nTPM]":"20.9","Single Cell Type RNA - Adipocytes [nTPM]":"8.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.6","Single Cell Type RNA - Astrocytes [nTPM]":"7.5","Single Cell Type RNA - B-cells [nTPM]":"10.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"31.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"23.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"33.6","Single Cell Type RNA - Bipolar cells [nTPM]":"14.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"13.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"74.9","Single Cell Type RNA - dendritic cells [nTPM]":"5.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"15.6","Single Cell Type RNA - Early spermatids [nTPM]":"147.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.6","Single Cell Type RNA - Endothelial cells [nTPM]":"9.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"13.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.4","Single Cell Type RNA - Fibroblasts [nTPM]":"7.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.7","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"13.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"14.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"19.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.5","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.0","Single Cell Type RNA - Langerhans cells [nTPM]":"8.0","Single Cell Type RNA - Late spermatids [nTPM]":"296.8","Single Cell Type RNA - Leydig cells [nTPM]":"8.7","Single Cell Type RNA - Macrophages [nTPM]":"5.5","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"8.9","Single Cell Type RNA - Muller glia cells [nTPM]":"9.3","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"23.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.2","Single Cell Type RNA - Paneth cells [nTPM]":"9.3","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"12.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"39.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.2","Single Cell Type RNA - Spermatocytes [nTPM]":"17.7","Single Cell Type RNA - Spermatogonia [nTPM]":"21.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"31.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"28.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"29.3","Single Cell Type RNA - T-cells [nTPM]":"9.4","Single Cell Type RNA - Theca cells [nTPM]":"11.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.1","Single Cell Type RNA - Urothelial cells [nTPM]":"13.0"},{"Gene":"PGK1","Gene synonym":[],"Ensembl":"ENSG00000102144","Gene description":"Phosphoglycerate kinase 1","Uniprot":["P00558"],"Chromosome":"X","Position":"77910739-78129295","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Glycolysis"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant","Hereditary hemolytic anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"1126.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010065","HPA045385","HPA073644","HPA073656"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB010065":"AB_628116","HPA045385":"AB_2679306","HPA073644":"AB_2732231","HPA073656":"AB_2732235"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.05e-8"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.69e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.65e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.74e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.34e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-2"},"Tissue RNA - adipose tissue [nTPM]":"120.7","Tissue RNA - adrenal gland [nTPM]":"141.8","Tissue RNA - amygdala [nTPM]":"87.3","Tissue RNA - appendix [nTPM]":"149.0","Tissue RNA - basal ganglia [nTPM]":"94.1","Tissue RNA - bone marrow [nTPM]":"252.8","Tissue RNA - breast [nTPM]":"89.1","Tissue RNA - cerebellum [nTPM]":"103.2","Tissue RNA - cerebral cortex [nTPM]":"119.0","Tissue RNA - cervix [nTPM]":"100.2","Tissue RNA - choroid plexus [nTPM]":"117.2","Tissue RNA - colon [nTPM]":"127.4","Tissue RNA - duodenum [nTPM]":"123.4","Tissue RNA - endometrium 1 [nTPM]":"72.3","Tissue RNA - epididymis [nTPM]":"73.0","Tissue RNA - esophagus [nTPM]":"154.1","Tissue RNA - fallopian tube [nTPM]":"79.3","Tissue RNA - gallbladder [nTPM]":"110.1","Tissue RNA - heart muscle [nTPM]":"247.4","Tissue RNA - hippocampal formation [nTPM]":"92.7","Tissue RNA - hypothalamus [nTPM]":"109.2","Tissue RNA - kidney [nTPM]":"233.5","Tissue RNA - liver [nTPM]":"143.8","Tissue RNA - lung [nTPM]":"117.1","Tissue RNA - lymph node [nTPM]":"139.0","Tissue RNA - medulla oblongata [nTPM]":"104.8","Tissue RNA - midbrain [nTPM]":"95.1","Tissue RNA - ovary [nTPM]":"61.9","Tissue RNA - pancreas [nTPM]":"61.1","Tissue RNA - parathyroid gland [nTPM]":"188.8","Tissue RNA - pituitary gland [nTPM]":"30.0","Tissue RNA - placenta [nTPM]":"138.6","Tissue RNA - pons [nTPM]":"109.5","Tissue RNA - prostate [nTPM]":"92.8","Tissue RNA - rectum [nTPM]":"143.1","Tissue RNA - retina [nTPM]":"298.8","Tissue RNA - salivary gland [nTPM]":"93.2","Tissue RNA - seminal vesicle [nTPM]":"101.8","Tissue RNA - skeletal muscle [nTPM]":"452.0","Tissue RNA - skin 1 [nTPM]":"92.6","Tissue RNA - small intestine [nTPM]":"119.1","Tissue RNA - smooth muscle [nTPM]":"116.7","Tissue RNA - spinal cord [nTPM]":"102.4","Tissue RNA - spleen [nTPM]":"97.2","Tissue RNA - stomach 1 [nTPM]":"86.1","Tissue RNA - testis [nTPM]":"29.2","Tissue RNA - thalamus [nTPM]":"111.1","Tissue RNA - thymus [nTPM]":"158.3","Tissue RNA - thyroid gland [nTPM]":"105.6","Tissue RNA - tongue [nTPM]":"266.7","Tissue RNA - tonsil [nTPM]":"189.6","Tissue RNA - urinary bladder [nTPM]":"148.4","Tissue RNA - vagina [nTPM]":"49.4","Tissue RNA - white matter [nTPM]":"101.3","Cell RNA - A-431 [nTPM]":"943.0","Cell RNA - A549 [nTPM]":"426.7","Cell RNA - AF22 [nTPM]":"139.7","Cell RNA - AN3-CA [nTPM]":"283.8","Cell RNA - ASC diff [nTPM]":"236.1","Cell RNA - ASC TERT1 [nTPM]":"190.0","Cell RNA - BEWO [nTPM]":"331.3","Cell RNA - BJ [nTPM]":"469.2","Cell RNA - BJ hTERT+ [nTPM]":"324.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"402.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"670.0","Cell RNA - CACO-2 [nTPM]":"390.2","Cell RNA - CAPAN-2 [nTPM]":"287.7","Cell RNA - Daudi [nTPM]":"373.9","Cell RNA - EFO-21 [nTPM]":"473.7","Cell RNA - fHDF\/TERT166 [nTPM]":"326.5","Cell RNA - GAMG [nTPM]":"479.5","Cell RNA - HaCaT [nTPM]":"397.6","Cell RNA - HAP1 [nTPM]":"624.8","Cell RNA - HBEC3-KT [nTPM]":"729.3","Cell RNA - HBF TERT88 [nTPM]":"800.7","Cell RNA - HDLM-2 [nTPM]":"229.8","Cell RNA - HEK 293 [nTPM]":"246.6","Cell RNA - HEL [nTPM]":"290.3","Cell RNA - HeLa [nTPM]":"657.8","Cell RNA - Hep G2 [nTPM]":"341.8","Cell RNA - HHSteC [nTPM]":"258.0","Cell RNA - HL-60 [nTPM]":"671.8","Cell RNA - HMC-1 [nTPM]":"309.2","Cell RNA - HSkMC [nTPM]":"238.5","Cell RNA - hTCEpi [nTPM]":"302.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"366.7","Cell RNA - hTERT-HME1 [nTPM]":"192.7","Cell RNA - hTERT-RPE1 [nTPM]":"646.1","Cell RNA - HUVEC TERT2 [nTPM]":"418.8","Cell RNA - JURKAT [nTPM]":"361.9","Cell RNA - K-562 [nTPM]":"308.5","Cell RNA - Karpas-707 [nTPM]":"553.4","Cell RNA - LHCN-M2 [nTPM]":"557.4","Cell RNA - MCF7 [nTPM]":"371.2","Cell RNA - MOLT-4 [nTPM]":"593.5","Cell RNA - NB-4 [nTPM]":"506.0","Cell RNA - NTERA-2 [nTPM]":"433.3","Cell RNA - OE19 [nTPM]":"628.5","Cell RNA - PC-3 [nTPM]":"800.7","Cell RNA - REH [nTPM]":"421.8","Cell RNA - RH-30 [nTPM]":"374.4","Cell RNA - RPMI-8226 [nTPM]":"1157.0","Cell RNA - RPTEC TERT1 [nTPM]":"423.8","Cell RNA - RT4 [nTPM]":"385.4","Cell RNA - SCLC-21H [nTPM]":"208.0","Cell RNA - SH-SY5Y [nTPM]":"286.6","Cell RNA - SiHa [nTPM]":"486.3","Cell RNA - SK-BR-3 [nTPM]":"409.0","Cell RNA - SK-MEL-30 [nTPM]":"422.9","Cell RNA - SuSa [nTPM]":"352.6","Cell RNA - T-47d [nTPM]":"214.8","Cell RNA - THP-1 [nTPM]":"347.9","Cell RNA - TIME [nTPM]":"340.2","Cell RNA - U-138 MG [nTPM]":"428.1","Cell RNA - U-2 OS [nTPM]":"294.3","Cell RNA - U-2197 [nTPM]":"433.4","Cell RNA - U-251 MG [nTPM]":"329.0","Cell RNA - U-266\/70 [nTPM]":"609.5","Cell RNA - U-266\/84 [nTPM]":"1221.7","Cell RNA - U-698 [nTPM]":"391.5","Cell RNA - U-87 MG [nTPM]":"1207.0","Cell RNA - U-937 [nTPM]":"750.5","Cell RNA - WM-115 [nTPM]":"286.6","Blood RNA - basophil [nTPM]":"170.6","Blood RNA - classical monocyte [nTPM]":"360.2","Blood RNA - eosinophil [nTPM]":"321.1","Blood RNA - gdT-cell [nTPM]":"121.9","Blood RNA - intermediate monocyte [nTPM]":"382.0","Blood RNA - MAIT T-cell [nTPM]":"135.9","Blood RNA - memory B-cell [nTPM]":"128.4","Blood RNA - memory CD4 T-cell [nTPM]":"144.3","Blood RNA - memory CD8 T-cell [nTPM]":"132.9","Blood RNA - myeloid DC [nTPM]":"333.7","Blood RNA - naive B-cell [nTPM]":"101.2","Blood RNA - naive CD4 T-cell [nTPM]":"130.9","Blood RNA - naive CD8 T-cell [nTPM]":"140.7","Blood RNA - neutrophil [nTPM]":"281.9","Blood RNA - NK-cell [nTPM]":"140.3","Blood RNA - non-classical monocyte [nTPM]":"527.0","Blood RNA - plasmacytoid DC [nTPM]":"130.2","Blood RNA - T-reg [nTPM]":"168.4","Blood RNA - total PBMC [nTPM]":"606.0","Brain RNA - amygdala [nTPM]":"87.3","Brain RNA - basal ganglia [nTPM]":"94.1","Brain RNA - cerebellum [nTPM]":"103.2","Brain RNA - cerebral cortex [nTPM]":"119.0","Brain RNA - hippocampal formation [nTPM]":"92.7","Brain RNA - hypothalamus [nTPM]":"109.2","Brain RNA - medulla oblongata [nTPM]":"104.8","Brain RNA - midbrain [nTPM]":"95.1","Brain RNA - pons [nTPM]":"109.5","Brain RNA - spinal cord [nTPM]":"102.4","Brain RNA - thalamus [nTPM]":"111.1","Brain RNA - white matter [nTPM]":"101.3","Single Cell Type RNA - Adipocytes [nTPM]":"166.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"150.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"168.6","Single Cell Type RNA - Astrocytes [nTPM]":"20.2","Single Cell Type RNA - B-cells [nTPM]":"174.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"144.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"272.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1126.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"122.3","Single Cell Type RNA - Bipolar cells [nTPM]":"211.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"72.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"67.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"480.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"140.2","Single Cell Type RNA - Club cells [nTPM]":"436.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"174.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"77.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"298.4","Single Cell Type RNA - dendritic cells [nTPM]":"200.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"196.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"471.6","Single Cell Type RNA - Ductal cells [nTPM]":"715.8","Single Cell Type RNA - Early spermatids [nTPM]":"19.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"123.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"112.4","Single Cell Type RNA - Endothelial cells [nTPM]":"182.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"102.4","Single Cell Type RNA - Erythroid cells [nTPM]":"95.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"32.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"236.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"746.4","Single Cell Type RNA - Fibroblasts [nTPM]":"131.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"95.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"145.1","Single Cell Type RNA - granulocytes [nTPM]":"195.5","Single Cell Type RNA - Granulosa cells [nTPM]":"98.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"139.6","Single Cell Type RNA - Hepatocytes [nTPM]":"200.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"499.0","Single Cell Type RNA - Horizontal cells [nTPM]":"309.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"164.3","Single Cell Type RNA - Ionocytes [nTPM]":"518.8","Single Cell Type RNA - Kupffer cells [nTPM]":"298.4","Single Cell Type RNA - Langerhans cells [nTPM]":"188.8","Single Cell Type RNA - Late spermatids [nTPM]":"12.1","Single Cell Type RNA - Leydig cells [nTPM]":"94.8","Single Cell Type RNA - Macrophages [nTPM]":"310.4","Single Cell Type RNA - Melanocytes [nTPM]":"167.2","Single Cell Type RNA - Microglial cells [nTPM]":"25.3","Single Cell Type RNA - monocytes [nTPM]":"499.3","Single Cell Type RNA - Muller glia cells [nTPM]":"245.7","Single Cell Type RNA - NK-cells [nTPM]":"131.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"510.2","Single Cell Type RNA - Paneth cells [nTPM]":"149.9","Single Cell Type RNA - Peritubular cells [nTPM]":"127.2","Single Cell Type RNA - Plasma cells [nTPM]":"214.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"118.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"221.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"566.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"235.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"188.8","Single Cell Type RNA - Sertoli cells [nTPM]":"124.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"84.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"191.8","Single Cell Type RNA - Spermatocytes [nTPM]":"8.8","Single Cell Type RNA - Spermatogonia [nTPM]":"57.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"138.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"119.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"349.6","Single Cell Type RNA - T-cells [nTPM]":"251.9","Single Cell Type RNA - Theca cells [nTPM]":"278.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"203.5","Single Cell Type RNA - Urothelial cells [nTPM]":"225.8"},{"Gene":"PGM1","Gene synonym":[],"Ensembl":"ENSG00000079739","Gene description":"Phosphoglucomutase 1","Uniprot":["P36871"],"Chromosome":"1","Position":"63593411-63660245","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism","Glucose metabolism"],"Molecular function":["Isomerase"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant","Glycogen storage disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"skeletal muscle":"1559.1","tongue":"788.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Exocrine glandular cells":"238.4","Extravillous trophoblasts":"185.9","Hepatocytes":"214.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004666","HPA024190","HPA024637","HPA046329"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"21000000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB004666":"AB_425590","HPA024190":"AB_1855266","HPA024637":"AB_1855267","HPA046329":"AB_2679625"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.74e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-3"},"Tissue RNA - adipose tissue [nTPM]":"113.7","Tissue RNA - adrenal gland [nTPM]":"70.8","Tissue RNA - amygdala [nTPM]":"31.6","Tissue RNA - appendix [nTPM]":"20.7","Tissue RNA - basal ganglia [nTPM]":"34.7","Tissue RNA - bone marrow [nTPM]":"21.5","Tissue RNA - breast [nTPM]":"57.4","Tissue RNA - cerebellum [nTPM]":"34.3","Tissue RNA - cerebral cortex [nTPM]":"38.4","Tissue RNA - cervix [nTPM]":"33.9","Tissue RNA - choroid plexus [nTPM]":"53.1","Tissue RNA - colon [nTPM]":"58.9","Tissue RNA - duodenum [nTPM]":"60.8","Tissue RNA - endometrium 1 [nTPM]":"22.9","Tissue RNA - epididymis [nTPM]":"19.2","Tissue RNA - esophagus [nTPM]":"49.3","Tissue RNA - fallopian tube [nTPM]":"17.0","Tissue RNA - gallbladder [nTPM]":"30.3","Tissue RNA - heart muscle [nTPM]":"178.9","Tissue RNA - hippocampal formation [nTPM]":"31.4","Tissue RNA - hypothalamus [nTPM]":"34.0","Tissue RNA - kidney [nTPM]":"52.2","Tissue RNA - liver [nTPM]":"279.8","Tissue RNA - lung [nTPM]":"42.6","Tissue RNA - lymph node [nTPM]":"14.7","Tissue RNA - medulla oblongata [nTPM]":"44.7","Tissue RNA - midbrain [nTPM]":"34.1","Tissue RNA - ovary [nTPM]":"51.0","Tissue RNA - pancreas [nTPM]":"112.2","Tissue RNA - parathyroid gland [nTPM]":"65.3","Tissue RNA - pituitary gland [nTPM]":"31.8","Tissue RNA - placenta [nTPM]":"26.9","Tissue RNA - pons [nTPM]":"32.7","Tissue RNA - prostate [nTPM]":"46.6","Tissue RNA - rectum [nTPM]":"49.9","Tissue RNA - retina [nTPM]":"22.6","Tissue RNA - salivary gland [nTPM]":"41.8","Tissue RNA - seminal vesicle [nTPM]":"49.7","Tissue RNA - skeletal muscle [nTPM]":"1559.1","Tissue RNA - skin 1 [nTPM]":"30.6","Tissue RNA - small intestine [nTPM]":"55.1","Tissue RNA - smooth muscle [nTPM]":"41.4","Tissue RNA - spinal cord [nTPM]":"31.9","Tissue RNA - spleen [nTPM]":"14.7","Tissue RNA - stomach 1 [nTPM]":"30.6","Tissue RNA - testis [nTPM]":"11.1","Tissue RNA - thalamus [nTPM]":"36.5","Tissue RNA - thymus [nTPM]":"14.3","Tissue RNA - thyroid gland [nTPM]":"27.5","Tissue RNA - tongue [nTPM]":"788.0","Tissue RNA - tonsil [nTPM]":"19.4","Tissue RNA - urinary bladder [nTPM]":"38.4","Tissue RNA - vagina [nTPM]":"22.1","Tissue RNA - white matter [nTPM]":"30.2","Cell RNA - A-431 [nTPM]":"113.4","Cell RNA - A549 [nTPM]":"47.0","Cell RNA - AF22 [nTPM]":"17.3","Cell RNA - AN3-CA [nTPM]":"57.0","Cell RNA - ASC diff [nTPM]":"111.0","Cell RNA - ASC TERT1 [nTPM]":"81.4","Cell RNA - BEWO [nTPM]":"138.6","Cell RNA - BJ [nTPM]":"45.7","Cell RNA - BJ hTERT+ [nTPM]":"61.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"48.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"79.0","Cell RNA - CACO-2 [nTPM]":"38.8","Cell RNA - CAPAN-2 [nTPM]":"51.3","Cell RNA - Daudi [nTPM]":"35.8","Cell RNA - EFO-21 [nTPM]":"93.2","Cell RNA - fHDF\/TERT166 [nTPM]":"71.2","Cell RNA - GAMG [nTPM]":"107.4","Cell RNA - HaCaT [nTPM]":"26.5","Cell RNA - HAP1 [nTPM]":"24.0","Cell RNA - HBEC3-KT [nTPM]":"96.3","Cell RNA - HBF TERT88 [nTPM]":"55.9","Cell RNA - HDLM-2 [nTPM]":"44.0","Cell RNA - HEK 293 [nTPM]":"32.1","Cell RNA - HEL [nTPM]":"75.3","Cell RNA - HeLa [nTPM]":"72.6","Cell RNA - Hep G2 [nTPM]":"40.3","Cell RNA - HHSteC [nTPM]":"91.6","Cell RNA - HL-60 [nTPM]":"66.8","Cell RNA - HMC-1 [nTPM]":"4.3","Cell RNA - HSkMC [nTPM]":"103.4","Cell RNA - hTCEpi [nTPM]":"60.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"57.1","Cell RNA - hTERT-HME1 [nTPM]":"88.5","Cell RNA - hTERT-RPE1 [nTPM]":"129.8","Cell RNA - HUVEC TERT2 [nTPM]":"29.6","Cell RNA - JURKAT [nTPM]":"36.3","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"46.3","Cell RNA - LHCN-M2 [nTPM]":"78.8","Cell RNA - MCF7 [nTPM]":"6.9","Cell RNA - MOLT-4 [nTPM]":"19.6","Cell RNA - NB-4 [nTPM]":"36.7","Cell RNA - NTERA-2 [nTPM]":"78.3","Cell RNA - OE19 [nTPM]":"3.4","Cell RNA - PC-3 [nTPM]":"73.9","Cell RNA - REH [nTPM]":"26.8","Cell RNA - RH-30 [nTPM]":"80.0","Cell RNA - RPMI-8226 [nTPM]":"11.8","Cell RNA - RPTEC TERT1 [nTPM]":"70.0","Cell RNA - RT4 [nTPM]":"35.3","Cell RNA - SCLC-21H [nTPM]":"10.4","Cell RNA - SH-SY5Y [nTPM]":"66.7","Cell RNA - SiHa [nTPM]":"100.0","Cell RNA - SK-BR-3 [nTPM]":"103.0","Cell RNA - SK-MEL-30 [nTPM]":"157.4","Cell RNA - SuSa [nTPM]":"78.6","Cell RNA - T-47d [nTPM]":"32.4","Cell RNA - THP-1 [nTPM]":"25.2","Cell RNA - TIME [nTPM]":"3.1","Cell RNA - U-138 MG [nTPM]":"71.6","Cell RNA - U-2 OS [nTPM]":"36.0","Cell RNA - U-2197 [nTPM]":"64.0","Cell RNA - U-251 MG [nTPM]":"39.4","Cell RNA - U-266\/70 [nTPM]":"29.1","Cell RNA - U-266\/84 [nTPM]":"45.5","Cell RNA - U-698 [nTPM]":"57.8","Cell RNA - U-87 MG [nTPM]":"117.0","Cell RNA - U-937 [nTPM]":"58.0","Cell RNA - WM-115 [nTPM]":"31.5","Blood RNA - basophil [nTPM]":"46.0","Blood RNA - classical monocyte [nTPM]":"33.2","Blood RNA - eosinophil [nTPM]":"49.2","Blood RNA - gdT-cell [nTPM]":"40.5","Blood RNA - intermediate monocyte [nTPM]":"22.4","Blood RNA - MAIT T-cell [nTPM]":"32.7","Blood RNA - memory B-cell [nTPM]":"22.4","Blood RNA - memory CD4 T-cell [nTPM]":"23.5","Blood RNA - memory CD8 T-cell [nTPM]":"31.0","Blood RNA - myeloid DC [nTPM]":"48.4","Blood RNA - naive B-cell [nTPM]":"11.8","Blood RNA - naive CD4 T-cell [nTPM]":"21.0","Blood RNA - naive CD8 T-cell [nTPM]":"24.7","Blood RNA - neutrophil [nTPM]":"38.7","Blood RNA - NK-cell [nTPM]":"43.9","Blood RNA - non-classical monocyte [nTPM]":"21.2","Blood RNA - plasmacytoid DC [nTPM]":"13.9","Blood RNA - T-reg [nTPM]":"20.4","Blood RNA - total PBMC [nTPM]":"35.4","Brain RNA - amygdala [nTPM]":"31.6","Brain RNA - basal ganglia [nTPM]":"34.7","Brain RNA - cerebellum [nTPM]":"34.3","Brain RNA - cerebral cortex [nTPM]":"38.4","Brain RNA - hippocampal formation [nTPM]":"31.4","Brain RNA - hypothalamus [nTPM]":"34.0","Brain RNA - medulla oblongata [nTPM]":"44.7","Brain RNA - midbrain [nTPM]":"34.1","Brain RNA - pons [nTPM]":"32.7","Brain RNA - spinal cord [nTPM]":"31.9","Brain RNA - thalamus [nTPM]":"36.5","Brain RNA - white matter [nTPM]":"30.2","Single Cell Type RNA - Adipocytes [nTPM]":"8.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"93.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.4","Single Cell Type RNA - Astrocytes [nTPM]":"48.3","Single Cell Type RNA - B-cells [nTPM]":"16.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"29.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"58.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"47.8","Single Cell Type RNA - Bipolar cells [nTPM]":"9.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"33.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"139.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"48.6","Single Cell Type RNA - Club cells [nTPM]":"24.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"76.6","Single Cell Type RNA - dendritic cells [nTPM]":"14.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"81.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"88.0","Single Cell Type RNA - Ductal cells [nTPM]":"55.9","Single Cell Type RNA - Early spermatids [nTPM]":"32.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.1","Single Cell Type RNA - Endothelial cells [nTPM]":"12.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"5.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"238.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"185.9","Single Cell Type RNA - Fibroblasts [nTPM]":"37.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"27.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.5","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"134.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.0","Single Cell Type RNA - Hepatocytes [nTPM]":"214.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"26.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"47.5","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"17.0","Single Cell Type RNA - Langerhans cells [nTPM]":"10.8","Single Cell Type RNA - Late spermatids [nTPM]":"8.5","Single Cell Type RNA - Leydig cells [nTPM]":"22.1","Single Cell Type RNA - Macrophages [nTPM]":"13.5","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"32.8","Single Cell Type RNA - Muller glia cells [nTPM]":"75.8","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"32.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"70.5","Single Cell Type RNA - Paneth cells [nTPM]":"31.6","Single Cell Type RNA - Peritubular cells [nTPM]":"38.0","Single Cell Type RNA - Plasma cells [nTPM]":"40.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"29.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"90.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"74.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.4","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"53.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"25.5","Single Cell Type RNA - Spermatocytes [nTPM]":"5.6","Single Cell Type RNA - Spermatogonia [nTPM]":"10.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"57.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"58.8","Single Cell Type RNA - T-cells [nTPM]":"19.0","Single Cell Type RNA - Theca cells [nTPM]":"20.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"81.5","Single Cell Type RNA - Urothelial cells [nTPM]":"19.0"},{"Gene":"PGM3","Gene synonym":["AGM1","DKFZP434B187","PAGM"],"Ensembl":"ENSG00000013375","Gene description":"Phosphoglucomutase 3","Uniprot":["O95394"],"Chromosome":"6","Position":"83161150-83193936","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism"],"Molecular function":["Isomerase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004998","HPA029759","HPA029760"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"220000","Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB004998":"AB_425591","HPA029759":"AB_10600305","HPA029760":"AB_10601109"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.78e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.67e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.96e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.39e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-3"},"Tissue RNA - adipose tissue [nTPM]":"23.6","Tissue RNA - adrenal gland [nTPM]":"21.0","Tissue RNA - amygdala [nTPM]":"12.0","Tissue RNA - appendix [nTPM]":"18.1","Tissue RNA - basal ganglia [nTPM]":"12.9","Tissue RNA - bone marrow [nTPM]":"9.3","Tissue RNA - breast [nTPM]":"18.0","Tissue RNA - cerebellum [nTPM]":"20.2","Tissue RNA - cerebral cortex [nTPM]":"15.2","Tissue RNA - cervix [nTPM]":"24.4","Tissue RNA - choroid plexus [nTPM]":"19.6","Tissue RNA - colon [nTPM]":"18.0","Tissue RNA - duodenum [nTPM]":"15.8","Tissue RNA - endometrium 1 [nTPM]":"17.1","Tissue RNA - epididymis [nTPM]":"34.5","Tissue RNA - esophagus [nTPM]":"12.3","Tissue RNA - fallopian tube [nTPM]":"13.4","Tissue RNA - gallbladder [nTPM]":"24.6","Tissue RNA - heart muscle [nTPM]":"14.3","Tissue RNA - hippocampal formation [nTPM]":"9.7","Tissue RNA - hypothalamus [nTPM]":"10.5","Tissue RNA - kidney [nTPM]":"13.6","Tissue RNA - liver [nTPM]":"38.3","Tissue RNA - lung [nTPM]":"16.8","Tissue RNA - lymph node [nTPM]":"11.2","Tissue RNA - medulla oblongata [nTPM]":"10.9","Tissue RNA - midbrain [nTPM]":"10.2","Tissue RNA - ovary [nTPM]":"22.7","Tissue RNA - pancreas [nTPM]":"46.1","Tissue RNA - parathyroid gland [nTPM]":"13.3","Tissue RNA - pituitary gland [nTPM]":"28.2","Tissue RNA - placenta [nTPM]":"47.5","Tissue RNA - pons [nTPM]":"13.1","Tissue RNA - prostate [nTPM]":"51.0","Tissue RNA - rectum [nTPM]":"23.4","Tissue RNA - retina [nTPM]":"26.8","Tissue RNA - salivary gland [nTPM]":"35.8","Tissue RNA - seminal vesicle [nTPM]":"20.3","Tissue RNA - skeletal muscle [nTPM]":"6.7","Tissue RNA - skin 1 [nTPM]":"10.9","Tissue RNA - small intestine [nTPM]":"18.2","Tissue RNA - smooth muscle [nTPM]":"18.5","Tissue RNA - spinal cord [nTPM]":"6.6","Tissue RNA - spleen [nTPM]":"11.5","Tissue RNA - stomach 1 [nTPM]":"24.9","Tissue RNA - testis [nTPM]":"32.3","Tissue RNA - thalamus [nTPM]":"11.1","Tissue RNA - thymus [nTPM]":"8.2","Tissue RNA - thyroid gland [nTPM]":"25.6","Tissue RNA - tongue [nTPM]":"8.6","Tissue RNA - tonsil [nTPM]":"15.2","Tissue RNA - urinary bladder [nTPM]":"19.0","Tissue RNA - vagina [nTPM]":"12.3","Tissue RNA - white matter [nTPM]":"15.9","Cell RNA - A-431 [nTPM]":"35.1","Cell RNA - A549 [nTPM]":"23.4","Cell RNA - AF22 [nTPM]":"41.8","Cell RNA - AN3-CA [nTPM]":"51.0","Cell RNA - ASC diff [nTPM]":"68.9","Cell RNA - ASC TERT1 [nTPM]":"72.9","Cell RNA - BEWO [nTPM]":"48.9","Cell RNA - BJ [nTPM]":"118.1","Cell RNA - BJ hTERT+ [nTPM]":"82.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"55.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"83.3","Cell RNA - CACO-2 [nTPM]":"60.1","Cell RNA - CAPAN-2 [nTPM]":"16.1","Cell RNA - Daudi [nTPM]":"18.3","Cell RNA - EFO-21 [nTPM]":"24.7","Cell RNA - fHDF\/TERT166 [nTPM]":"112.3","Cell RNA - GAMG [nTPM]":"53.0","Cell RNA - HaCaT [nTPM]":"20.1","Cell RNA - HAP1 [nTPM]":"38.4","Cell RNA - HBEC3-KT [nTPM]":"49.5","Cell RNA - HBF TERT88 [nTPM]":"104.6","Cell RNA - HDLM-2 [nTPM]":"14.6","Cell RNA - HEK 293 [nTPM]":"37.8","Cell RNA - HEL [nTPM]":"22.7","Cell RNA - HeLa [nTPM]":"41.9","Cell RNA - Hep G2 [nTPM]":"105.0","Cell RNA - HHSteC [nTPM]":"77.6","Cell RNA - HL-60 [nTPM]":"22.6","Cell RNA - HMC-1 [nTPM]":"11.2","Cell RNA - HSkMC [nTPM]":"46.2","Cell RNA - hTCEpi [nTPM]":"40.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"96.6","Cell RNA - hTERT-HME1 [nTPM]":"120.0","Cell RNA - hTERT-RPE1 [nTPM]":"55.5","Cell RNA - HUVEC TERT2 [nTPM]":"64.6","Cell RNA - JURKAT [nTPM]":"12.1","Cell RNA - K-562 [nTPM]":"74.9","Cell RNA - Karpas-707 [nTPM]":"19.6","Cell RNA - LHCN-M2 [nTPM]":"61.0","Cell RNA - MCF7 [nTPM]":"39.1","Cell RNA - MOLT-4 [nTPM]":"3.7","Cell RNA - NB-4 [nTPM]":"14.7","Cell RNA - NTERA-2 [nTPM]":"18.8","Cell RNA - OE19 [nTPM]":"31.8","Cell RNA - PC-3 [nTPM]":"31.6","Cell RNA - REH [nTPM]":"16.2","Cell RNA - RH-30 [nTPM]":"92.5","Cell RNA - RPMI-8226 [nTPM]":"11.3","Cell RNA - RPTEC TERT1 [nTPM]":"42.0","Cell RNA - RT4 [nTPM]":"36.0","Cell RNA - SCLC-21H [nTPM]":"16.9","Cell RNA - SH-SY5Y [nTPM]":"26.3","Cell RNA - SiHa [nTPM]":"34.8","Cell RNA - SK-BR-3 [nTPM]":"28.5","Cell RNA - SK-MEL-30 [nTPM]":"20.9","Cell RNA - SuSa [nTPM]":"61.8","Cell RNA - T-47d [nTPM]":"27.0","Cell RNA - THP-1 [nTPM]":"25.5","Cell RNA - TIME [nTPM]":"94.2","Cell RNA - U-138 MG [nTPM]":"38.3","Cell RNA - U-2 OS [nTPM]":"21.2","Cell RNA - U-2197 [nTPM]":"74.9","Cell RNA - U-251 MG [nTPM]":"60.5","Cell RNA - U-266\/70 [nTPM]":"36.5","Cell RNA - U-266\/84 [nTPM]":"16.1","Cell RNA - U-698 [nTPM]":"13.0","Cell RNA - U-87 MG [nTPM]":"29.7","Cell RNA - U-937 [nTPM]":"17.7","Cell RNA - WM-115 [nTPM]":"58.4","Blood RNA - basophil [nTPM]":"10.8","Blood RNA - classical monocyte [nTPM]":"4.1","Blood RNA - eosinophil [nTPM]":"2.7","Blood RNA - gdT-cell [nTPM]":"2.6","Blood RNA - intermediate monocyte [nTPM]":"3.5","Blood RNA - MAIT T-cell [nTPM]":"3.9","Blood RNA - memory B-cell [nTPM]":"4.6","Blood RNA - memory CD4 T-cell [nTPM]":"2.8","Blood RNA - memory CD8 T-cell [nTPM]":"3.4","Blood RNA - myeloid DC [nTPM]":"3.6","Blood RNA - naive B-cell [nTPM]":"2.5","Blood RNA - naive CD4 T-cell [nTPM]":"4.5","Blood RNA - naive CD8 T-cell [nTPM]":"4.7","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"3.5","Blood RNA - non-classical monocyte [nTPM]":"4.5","Blood RNA - plasmacytoid DC [nTPM]":"4.2","Blood RNA - T-reg [nTPM]":"2.1","Blood RNA - total PBMC [nTPM]":"2.3","Brain RNA - amygdala [nTPM]":"12.0","Brain RNA - basal ganglia [nTPM]":"12.9","Brain RNA - cerebellum [nTPM]":"20.2","Brain RNA - cerebral cortex [nTPM]":"15.2","Brain RNA - hippocampal formation [nTPM]":"9.7","Brain RNA - hypothalamus [nTPM]":"10.5","Brain RNA - medulla oblongata [nTPM]":"10.9","Brain RNA - midbrain [nTPM]":"10.2","Brain RNA - pons [nTPM]":"13.1","Brain RNA - spinal cord [nTPM]":"6.6","Brain RNA - thalamus [nTPM]":"11.1","Brain RNA - white matter [nTPM]":"15.9","Single Cell Type RNA - Adipocytes [nTPM]":"14.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.7","Single Cell Type RNA - Astrocytes [nTPM]":"14.4","Single Cell Type RNA - B-cells [nTPM]":"13.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"29.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"28.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"16.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"36.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"32.4","Single Cell Type RNA - dendritic cells [nTPM]":"12.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"31.7","Single Cell Type RNA - Early spermatids [nTPM]":"67.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"35.1","Single Cell Type RNA - Endothelial cells [nTPM]":"13.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.1","Single Cell Type RNA - Erythroid cells [nTPM]":"6.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"49.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"71.1","Single Cell Type RNA - Fibroblasts [nTPM]":"46.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"36.4","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"25.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.3","Single Cell Type RNA - Hepatocytes [nTPM]":"32.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.6","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"29.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"35.5","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"6.0","Single Cell Type RNA - Langerhans cells [nTPM]":"8.7","Single Cell Type RNA - Late spermatids [nTPM]":"20.9","Single Cell Type RNA - Leydig cells [nTPM]":"33.5","Single Cell Type RNA - Macrophages [nTPM]":"8.6","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"10.1","Single Cell Type RNA - Muller glia cells [nTPM]":"25.9","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"41.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"36.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"37.9","Single Cell Type RNA - Paneth cells [nTPM]":"19.7","Single Cell Type RNA - Peritubular cells [nTPM]":"18.4","Single Cell Type RNA - Plasma cells [nTPM]":"44.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"56.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"16.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.6","Single Cell Type RNA - Spermatocytes [nTPM]":"75.5","Single Cell Type RNA - Spermatogonia [nTPM]":"34.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"64.4","Single Cell Type RNA - T-cells [nTPM]":"10.1","Single Cell Type RNA - Theca cells [nTPM]":"12.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.6","Single Cell Type RNA - Urothelial cells [nTPM]":"25.6"},{"Gene":"PHEX","Gene synonym":["HPDR","HPDR1","HYP","HYP1","PEX","XLH"],"Ensembl":"ENSG00000102174","Gene description":"Phosphate regulating endopeptidase homolog X-linked","Uniprot":["P78562"],"Chromosome":"X","Position":"22032325-22251310","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Biomineralization"],"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"2.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"dendritic cells":"45.3","Granulosa cells":"161.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"thyroid cancer":"5.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"37","RNA blood cell specific nTPM":{"plasmacytoid DC":"4.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"37","RNA blood lineage specific nTPM":{"dendritic cells":"4.8"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HBEC3-KT":"3.7","HUVEC TERT2":"2.8","PC-3":"3.0","TIME":"3.1","U-87 MG":"6.5","WM-115":"2.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.51e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.68e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"1.0","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"1.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.7","Tissue RNA - cerebellum [nTPM]":"1.8","Tissue RNA - cerebral cortex [nTPM]":"0.7","Tissue RNA - cervix [nTPM]":"0.9","Tissue RNA - choroid plexus [nTPM]":"0.4","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"2.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.9","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.8","Tissue RNA - hypothalamus [nTPM]":"2.2","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"2.7","Tissue RNA - lymph node [nTPM]":"1.5","Tissue RNA - medulla oblongata [nTPM]":"1.6","Tissue RNA - midbrain [nTPM]":"1.6","Tissue RNA - ovary [nTPM]":"1.6","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"1.9","Tissue RNA - prostate [nTPM]":"0.6","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.6","Tissue RNA - smooth muscle [nTPM]":"1.5","Tissue RNA - spinal cord [nTPM]":"1.8","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"1.3","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"1.0","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"0.9","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"2.1","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.5","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.8","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"3.7","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"1.3","Cell RNA - hTCEpi [nTPM]":"0.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.7","Cell RNA - hTERT-HME1 [nTPM]":"2.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"2.8","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.3","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"3.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.6","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.4","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"1.5","Cell RNA - SK-MEL-30 [nTPM]":"0.5","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"1.8","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"3.1","Cell RNA - U-138 MG [nTPM]":"0.6","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.5","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"6.5","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"2.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"4.8","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.0","Brain RNA - basal ganglia [nTPM]":"1.0","Brain RNA - cerebellum [nTPM]":"1.8","Brain RNA - cerebral cortex [nTPM]":"0.7","Brain RNA - hippocampal formation [nTPM]":"0.8","Brain RNA - hypothalamus [nTPM]":"2.2","Brain RNA - medulla oblongata [nTPM]":"1.6","Brain RNA - midbrain [nTPM]":"1.6","Brain RNA - pons [nTPM]":"1.9","Brain RNA - spinal cord [nTPM]":"1.8","Brain RNA - thalamus [nTPM]":"1.3","Brain RNA - white matter [nTPM]":"2.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"3.9","Single Cell Type RNA - B-cells [nTPM]":"0.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"45.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"2.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"161.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.5","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"1.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"18.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"3.3"},{"Gene":"PHF8","Gene synonym":["JHDM1F","KDM7B","KIAA1111","ZNF422"],"Ensembl":"ENSG00000172943","Gene description":"PHD finger protein 8","Uniprot":["Q9UPP1"],"Chromosome":"X","Position":"53936676-54048958","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","Transcription","Transcription regulation"],"Molecular function":["Activator","Chromatin regulator","Dioxygenase","Oxidoreductase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"70.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"57.9","Spermatogonia":"58.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038779","HPA062015"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA038779":"AB_10675950","HPA062015":"AB_2684658"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.74e-5"},"Tissue RNA - adipose tissue [nTPM]":"11.6","Tissue RNA - adrenal gland [nTPM]":"8.1","Tissue RNA - amygdala [nTPM]":"8.3","Tissue RNA - appendix [nTPM]":"13.3","Tissue RNA - basal ganglia [nTPM]":"11.1","Tissue RNA - bone marrow [nTPM]":"16.2","Tissue RNA - breast [nTPM]":"13.8","Tissue RNA - cerebellum [nTPM]":"9.5","Tissue RNA - cerebral cortex [nTPM]":"10.3","Tissue RNA - cervix [nTPM]":"13.9","Tissue RNA - choroid plexus [nTPM]":"20.0","Tissue RNA - colon [nTPM]":"11.6","Tissue RNA - duodenum [nTPM]":"10.3","Tissue RNA - endometrium 1 [nTPM]":"14.1","Tissue RNA - epididymis [nTPM]":"70.6","Tissue RNA - esophagus [nTPM]":"13.4","Tissue RNA - fallopian tube [nTPM]":"14.1","Tissue RNA - gallbladder [nTPM]":"9.2","Tissue RNA - heart muscle [nTPM]":"9.8","Tissue RNA - hippocampal formation [nTPM]":"7.8","Tissue RNA - hypothalamus [nTPM]":"11.2","Tissue RNA - kidney [nTPM]":"9.7","Tissue RNA - liver [nTPM]":"28.7","Tissue RNA - lung [nTPM]":"13.5","Tissue RNA - lymph node [nTPM]":"16.3","Tissue RNA - medulla oblongata [nTPM]":"10.1","Tissue RNA - midbrain [nTPM]":"9.4","Tissue RNA - ovary [nTPM]":"19.3","Tissue RNA - pancreas [nTPM]":"17.8","Tissue RNA - parathyroid gland [nTPM]":"10.8","Tissue RNA - pituitary gland [nTPM]":"13.9","Tissue RNA - placenta [nTPM]":"13.2","Tissue RNA - pons [nTPM]":"11.2","Tissue RNA - prostate [nTPM]":"16.0","Tissue RNA - rectum [nTPM]":"9.6","Tissue RNA - retina [nTPM]":"14.6","Tissue RNA - salivary gland [nTPM]":"12.8","Tissue RNA - seminal vesicle [nTPM]":"18.3","Tissue RNA - skeletal muscle [nTPM]":"11.0","Tissue RNA - skin 1 [nTPM]":"13.1","Tissue RNA - small intestine [nTPM]":"14.2","Tissue RNA - smooth muscle [nTPM]":"9.4","Tissue RNA - spinal cord [nTPM]":"8.1","Tissue RNA - spleen [nTPM]":"13.9","Tissue RNA - stomach 1 [nTPM]":"12.7","Tissue RNA - testis [nTPM]":"40.1","Tissue RNA - thalamus [nTPM]":"10.2","Tissue RNA - thymus [nTPM]":"18.6","Tissue RNA - thyroid gland [nTPM]":"13.2","Tissue RNA - tongue [nTPM]":"7.8","Tissue RNA - tonsil [nTPM]":"15.8","Tissue RNA - urinary bladder [nTPM]":"14.1","Tissue RNA - vagina [nTPM]":"13.5","Tissue RNA - white matter [nTPM]":"13.3","Cell RNA - A-431 [nTPM]":"16.1","Cell RNA - A549 [nTPM]":"14.0","Cell RNA - AF22 [nTPM]":"20.4","Cell RNA - AN3-CA [nTPM]":"19.9","Cell RNA - ASC diff [nTPM]":"12.2","Cell RNA - ASC TERT1 [nTPM]":"9.6","Cell RNA - BEWO [nTPM]":"33.3","Cell RNA - BJ [nTPM]":"12.0","Cell RNA - BJ hTERT+ [nTPM]":"10.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.4","Cell RNA - CACO-2 [nTPM]":"15.7","Cell RNA - CAPAN-2 [nTPM]":"12.8","Cell RNA - Daudi [nTPM]":"23.4","Cell RNA - EFO-21 [nTPM]":"6.9","Cell RNA - fHDF\/TERT166 [nTPM]":"10.8","Cell RNA - GAMG [nTPM]":"13.9","Cell RNA - HaCaT [nTPM]":"16.5","Cell RNA - HAP1 [nTPM]":"51.1","Cell RNA - HBEC3-KT [nTPM]":"10.3","Cell RNA - HBF TERT88 [nTPM]":"13.7","Cell RNA - HDLM-2 [nTPM]":"36.4","Cell RNA - HEK 293 [nTPM]":"23.8","Cell RNA - HEL [nTPM]":"14.2","Cell RNA - HeLa [nTPM]":"18.1","Cell RNA - Hep G2 [nTPM]":"15.8","Cell RNA - HHSteC [nTPM]":"9.6","Cell RNA - HL-60 [nTPM]":"22.4","Cell RNA - HMC-1 [nTPM]":"25.6","Cell RNA - HSkMC [nTPM]":"10.9","Cell RNA - hTCEpi [nTPM]":"14.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.0","Cell RNA - hTERT-HME1 [nTPM]":"20.2","Cell RNA - hTERT-RPE1 [nTPM]":"9.7","Cell RNA - HUVEC TERT2 [nTPM]":"12.0","Cell RNA - JURKAT [nTPM]":"24.3","Cell RNA - K-562 [nTPM]":"18.7","Cell RNA - Karpas-707 [nTPM]":"33.2","Cell RNA - LHCN-M2 [nTPM]":"7.6","Cell RNA - MCF7 [nTPM]":"16.1","Cell RNA - MOLT-4 [nTPM]":"30.6","Cell RNA - NB-4 [nTPM]":"16.9","Cell RNA - NTERA-2 [nTPM]":"37.2","Cell RNA - OE19 [nTPM]":"11.0","Cell RNA - PC-3 [nTPM]":"19.6","Cell RNA - REH [nTPM]":"29.7","Cell RNA - RH-30 [nTPM]":"22.5","Cell RNA - RPMI-8226 [nTPM]":"22.9","Cell RNA - RPTEC TERT1 [nTPM]":"8.9","Cell RNA - RT4 [nTPM]":"19.2","Cell RNA - SCLC-21H [nTPM]":"29.2","Cell RNA - SH-SY5Y [nTPM]":"14.5","Cell RNA - SiHa [nTPM]":"31.6","Cell RNA - SK-BR-3 [nTPM]":"20.5","Cell RNA - SK-MEL-30 [nTPM]":"10.5","Cell RNA - SuSa [nTPM]":"31.2","Cell RNA - T-47d [nTPM]":"20.5","Cell RNA - THP-1 [nTPM]":"15.5","Cell RNA - TIME [nTPM]":"14.3","Cell RNA - U-138 MG [nTPM]":"10.3","Cell RNA - U-2 OS [nTPM]":"14.5","Cell RNA - U-2197 [nTPM]":"19.2","Cell RNA - U-251 MG [nTPM]":"10.0","Cell RNA - U-266\/70 [nTPM]":"25.1","Cell RNA - U-266\/84 [nTPM]":"25.4","Cell RNA - U-698 [nTPM]":"28.3","Cell RNA - U-87 MG [nTPM]":"12.2","Cell RNA - U-937 [nTPM]":"27.9","Cell RNA - WM-115 [nTPM]":"11.3","Blood RNA - basophil [nTPM]":"6.1","Blood RNA - classical monocyte [nTPM]":"2.7","Blood RNA - eosinophil [nTPM]":"4.4","Blood RNA - gdT-cell [nTPM]":"3.2","Blood RNA - intermediate monocyte [nTPM]":"4.8","Blood RNA - MAIT T-cell [nTPM]":"5.1","Blood RNA - memory B-cell [nTPM]":"2.3","Blood RNA - memory CD4 T-cell [nTPM]":"3.3","Blood RNA - memory CD8 T-cell [nTPM]":"3.9","Blood RNA - myeloid DC [nTPM]":"2.9","Blood RNA - naive B-cell [nTPM]":"3.1","Blood RNA - naive CD4 T-cell [nTPM]":"2.5","Blood RNA - naive CD8 T-cell [nTPM]":"2.8","Blood RNA - neutrophil [nTPM]":"4.4","Blood RNA - NK-cell [nTPM]":"3.5","Blood RNA - non-classical monocyte [nTPM]":"3.2","Blood RNA - plasmacytoid DC [nTPM]":"2.3","Blood RNA - T-reg [nTPM]":"5.3","Blood RNA - total PBMC [nTPM]":"3.4","Brain RNA - amygdala [nTPM]":"8.3","Brain RNA - basal ganglia [nTPM]":"11.1","Brain RNA - cerebellum [nTPM]":"9.5","Brain RNA - cerebral cortex [nTPM]":"10.3","Brain RNA - hippocampal formation [nTPM]":"7.8","Brain RNA - hypothalamus [nTPM]":"11.2","Brain RNA - medulla oblongata [nTPM]":"10.1","Brain RNA - midbrain [nTPM]":"9.4","Brain RNA - pons [nTPM]":"11.2","Brain RNA - spinal cord [nTPM]":"8.1","Brain RNA - thalamus [nTPM]":"10.2","Brain RNA - white matter [nTPM]":"13.3","Single Cell Type RNA - Adipocytes [nTPM]":"9.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.3","Single Cell Type RNA - Astrocytes [nTPM]":"17.3","Single Cell Type RNA - B-cells [nTPM]":"11.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Bipolar cells [nTPM]":"13.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"5.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.9","Single Cell Type RNA - dendritic cells [nTPM]":"14.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.1","Single Cell Type RNA - Early spermatids [nTPM]":"54.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"34.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.3","Single Cell Type RNA - Endothelial cells [nTPM]":"11.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.7","Single Cell Type RNA - Fibroblasts [nTPM]":"6.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"40.2","Single Cell Type RNA - granulocytes [nTPM]":"14.0","Single Cell Type RNA - Granulosa cells [nTPM]":"15.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"39.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.8","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.8","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"11.8","Single Cell Type RNA - Langerhans cells [nTPM]":"6.4","Single Cell Type RNA - Late spermatids [nTPM]":"31.4","Single Cell Type RNA - Leydig cells [nTPM]":"9.3","Single Cell Type RNA - Macrophages [nTPM]":"11.6","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"9.2","Single Cell Type RNA - Muller glia cells [nTPM]":"6.1","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"27.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"30.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.4","Single Cell Type RNA - Paneth cells [nTPM]":"9.4","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"14.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.2","Single Cell Type RNA - Spermatocytes [nTPM]":"57.9","Single Cell Type RNA - Spermatogonia [nTPM]":"58.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.2","Single Cell Type RNA - T-cells [nTPM]":"13.5","Single Cell Type RNA - Theca cells [nTPM]":"6.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.3","Single Cell Type RNA - Urothelial cells [nTPM]":"14.7"},{"Gene":"PHGDH","Gene synonym":["PDG","PGDH","SERA"],"Ensembl":"ENSG00000092621","Gene description":"Phosphoglycerate dehydrogenase","Uniprot":["O43175"],"Chromosome":"1","Position":"119648411-119744218","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Amino-acid biosynthesis","Serine biosynthesis"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"135.0","Exocrine glandular cells":"136.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD8 T-cell":"25.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SK-MEL-30":"975.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003681","HPA021241","HPA024031","CAB068216"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1100000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB003681":"AB_425928","CAB068216":"AB_2665666","HPA021241":"AB_1855299","HPA024031":"AB_1855300"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.48e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.62e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.80e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-3"},"Tissue RNA - adipose tissue [nTPM]":"51.4","Tissue RNA - adrenal gland [nTPM]":"3.0","Tissue RNA - amygdala [nTPM]":"113.6","Tissue RNA - appendix [nTPM]":"9.4","Tissue RNA - basal ganglia [nTPM]":"125.3","Tissue RNA - bone marrow [nTPM]":"11.4","Tissue RNA - breast [nTPM]":"30.1","Tissue RNA - cerebellum [nTPM]":"130.7","Tissue RNA - cerebral cortex [nTPM]":"125.9","Tissue RNA - cervix [nTPM]":"46.1","Tissue RNA - choroid plexus [nTPM]":"89.1","Tissue RNA - colon [nTPM]":"27.2","Tissue RNA - duodenum [nTPM]":"7.6","Tissue RNA - endometrium 1 [nTPM]":"25.4","Tissue RNA - epididymis [nTPM]":"79.6","Tissue RNA - esophagus [nTPM]":"56.6","Tissue RNA - fallopian tube [nTPM]":"49.3","Tissue RNA - gallbladder [nTPM]":"7.6","Tissue RNA - heart muscle [nTPM]":"22.4","Tissue RNA - hippocampal formation [nTPM]":"108.8","Tissue RNA - hypothalamus [nTPM]":"128.8","Tissue RNA - kidney [nTPM]":"40.9","Tissue RNA - liver [nTPM]":"126.0","Tissue RNA - lung [nTPM]":"18.0","Tissue RNA - lymph node [nTPM]":"14.9","Tissue RNA - medulla oblongata [nTPM]":"121.8","Tissue RNA - midbrain [nTPM]":"113.9","Tissue RNA - ovary [nTPM]":"46.1","Tissue RNA - pancreas [nTPM]":"171.1","Tissue RNA - parathyroid gland [nTPM]":"103.9","Tissue RNA - pituitary gland [nTPM]":"23.7","Tissue RNA - placenta [nTPM]":"13.2","Tissue RNA - pons [nTPM]":"122.4","Tissue RNA - prostate [nTPM]":"52.6","Tissue RNA - rectum [nTPM]":"7.0","Tissue RNA - retina [nTPM]":"7.5","Tissue RNA - salivary gland [nTPM]":"156.2","Tissue RNA - seminal vesicle [nTPM]":"33.5","Tissue RNA - skeletal muscle [nTPM]":"2.6","Tissue RNA - skin 1 [nTPM]":"92.5","Tissue RNA - small intestine [nTPM]":"13.3","Tissue RNA - smooth muscle [nTPM]":"15.0","Tissue RNA - spinal cord [nTPM]":"117.0","Tissue RNA - spleen [nTPM]":"6.5","Tissue RNA - stomach 1 [nTPM]":"41.7","Tissue RNA - testis [nTPM]":"40.3","Tissue RNA - thalamus [nTPM]":"115.8","Tissue RNA - thymus [nTPM]":"34.0","Tissue RNA - thyroid gland [nTPM]":"29.5","Tissue RNA - tongue [nTPM]":"4.3","Tissue RNA - tonsil [nTPM]":"13.3","Tissue RNA - urinary bladder [nTPM]":"35.8","Tissue RNA - vagina [nTPM]":"62.9","Tissue RNA - white matter [nTPM]":"153.6","Cell RNA - A-431 [nTPM]":"156.8","Cell RNA - A549 [nTPM]":"35.2","Cell RNA - AF22 [nTPM]":"148.0","Cell RNA - AN3-CA [nTPM]":"444.6","Cell RNA - ASC diff [nTPM]":"64.9","Cell RNA - ASC TERT1 [nTPM]":"82.8","Cell RNA - BEWO [nTPM]":"286.1","Cell RNA - BJ [nTPM]":"101.0","Cell RNA - BJ hTERT+ [nTPM]":"209.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"132.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"257.6","Cell RNA - CACO-2 [nTPM]":"195.7","Cell RNA - CAPAN-2 [nTPM]":"28.6","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"58.1","Cell RNA - fHDF\/TERT166 [nTPM]":"270.5","Cell RNA - GAMG [nTPM]":"16.6","Cell RNA - HaCaT [nTPM]":"205.6","Cell RNA - HAP1 [nTPM]":"216.8","Cell RNA - HBEC3-KT [nTPM]":"224.6","Cell RNA - HBF TERT88 [nTPM]":"83.9","Cell RNA - HDLM-2 [nTPM]":"1.1","Cell RNA - HEK 293 [nTPM]":"162.1","Cell RNA - HEL [nTPM]":"29.1","Cell RNA - HeLa [nTPM]":"151.3","Cell RNA - Hep G2 [nTPM]":"153.3","Cell RNA - HHSteC [nTPM]":"135.7","Cell RNA - HL-60 [nTPM]":"214.3","Cell RNA - HMC-1 [nTPM]":"1.7","Cell RNA - HSkMC [nTPM]":"147.6","Cell RNA - hTCEpi [nTPM]":"338.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"146.8","Cell RNA - hTERT-HME1 [nTPM]":"142.2","Cell RNA - hTERT-RPE1 [nTPM]":"83.0","Cell RNA - HUVEC TERT2 [nTPM]":"100.1","Cell RNA - JURKAT [nTPM]":"519.7","Cell RNA - K-562 [nTPM]":"71.4","Cell RNA - Karpas-707 [nTPM]":"443.9","Cell RNA - LHCN-M2 [nTPM]":"66.8","Cell RNA - MCF7 [nTPM]":"380.9","Cell RNA - MOLT-4 [nTPM]":"222.8","Cell RNA - NB-4 [nTPM]":"90.1","Cell RNA - NTERA-2 [nTPM]":"440.0","Cell RNA - OE19 [nTPM]":"93.3","Cell RNA - PC-3 [nTPM]":"274.6","Cell RNA - REH [nTPM]":"228.0","Cell RNA - RH-30 [nTPM]":"181.1","Cell RNA - RPMI-8226 [nTPM]":"24.8","Cell RNA - RPTEC TERT1 [nTPM]":"9.6","Cell RNA - RT4 [nTPM]":"120.4","Cell RNA - SCLC-21H [nTPM]":"160.8","Cell RNA - SH-SY5Y [nTPM]":"146.0","Cell RNA - SiHa [nTPM]":"65.9","Cell RNA - SK-BR-3 [nTPM]":"63.9","Cell RNA - SK-MEL-30 [nTPM]":"975.9","Cell RNA - SuSa [nTPM]":"103.9","Cell RNA - T-47d [nTPM]":"164.8","Cell RNA - THP-1 [nTPM]":"505.7","Cell RNA - TIME [nTPM]":"0.9","Cell RNA - U-138 MG [nTPM]":"38.3","Cell RNA - U-2 OS [nTPM]":"172.1","Cell RNA - U-2197 [nTPM]":"207.3","Cell RNA - U-251 MG [nTPM]":"134.8","Cell RNA - U-266\/70 [nTPM]":"294.0","Cell RNA - U-266\/84 [nTPM]":"79.9","Cell RNA - U-698 [nTPM]":"246.1","Cell RNA - U-87 MG [nTPM]":"456.9","Cell RNA - U-937 [nTPM]":"328.2","Cell RNA - WM-115 [nTPM]":"302.7","Blood RNA - basophil [nTPM]":"5.3","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"4.7","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"11.1","Blood RNA - memory CD4 T-cell [nTPM]":"2.4","Blood RNA - memory CD8 T-cell [nTPM]":"8.2","Blood RNA - myeloid DC [nTPM]":"5.3","Blood RNA - naive B-cell [nTPM]":"4.0","Blood RNA - naive CD4 T-cell [nTPM]":"13.0","Blood RNA - naive CD8 T-cell [nTPM]":"25.2","Blood RNA - neutrophil [nTPM]":"2.2","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"2.6","Blood RNA - T-reg [nTPM]":"4.5","Blood RNA - total PBMC [nTPM]":"6.3","Brain RNA - amygdala [nTPM]":"113.6","Brain RNA - basal ganglia [nTPM]":"125.3","Brain RNA - cerebellum [nTPM]":"130.7","Brain RNA - cerebral cortex [nTPM]":"125.9","Brain RNA - hippocampal formation [nTPM]":"108.8","Brain RNA - hypothalamus [nTPM]":"128.8","Brain RNA - medulla oblongata [nTPM]":"121.8","Brain RNA - midbrain [nTPM]":"113.9","Brain RNA - pons [nTPM]":"122.4","Brain RNA - spinal cord [nTPM]":"117.0","Brain RNA - thalamus [nTPM]":"115.8","Brain RNA - white matter [nTPM]":"153.6","Single Cell Type RNA - Adipocytes [nTPM]":"5.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.6","Single Cell Type RNA - Astrocytes [nTPM]":"31.6","Single Cell Type RNA - B-cells [nTPM]":"10.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"51.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"118.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"24.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"42.7","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"38.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"128.7","Single Cell Type RNA - Club cells [nTPM]":"12.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"49.9","Single Cell Type RNA - dendritic cells [nTPM]":"2.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"135.0","Single Cell Type RNA - Ductal cells [nTPM]":"60.2","Single Cell Type RNA - Early spermatids [nTPM]":"51.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.8","Single Cell Type RNA - Endothelial cells [nTPM]":"6.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"5.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"136.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"54.0","Single Cell Type RNA - Fibroblasts [nTPM]":"58.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.2","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"30.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"96.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.6","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"2.2","Single Cell Type RNA - Langerhans cells [nTPM]":"4.3","Single Cell Type RNA - Late spermatids [nTPM]":"116.9","Single Cell Type RNA - Leydig cells [nTPM]":"67.7","Single Cell Type RNA - Macrophages [nTPM]":"6.5","Single Cell Type RNA - Melanocytes [nTPM]":"56.9","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"11.0","Single Cell Type RNA - Muller glia cells [nTPM]":"82.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"32.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"35.6","Single Cell Type RNA - Paneth cells [nTPM]":"2.0","Single Cell Type RNA - Peritubular cells [nTPM]":"127.9","Single Cell Type RNA - Plasma cells [nTPM]":"27.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"62.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"118.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"24.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.4","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"48.8","Single Cell Type RNA - Spermatocytes [nTPM]":"20.0","Single Cell Type RNA - Spermatogonia [nTPM]":"19.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"57.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"77.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"25.3","Single Cell Type RNA - T-cells [nTPM]":"5.9","Single Cell Type RNA - Theca cells [nTPM]":"71.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.2","Single Cell Type RNA - Urothelial cells [nTPM]":"56.8"},{"Gene":"PHKG2","Gene synonym":[],"Ensembl":"ENSG00000156873","Gene description":"Phosphorylase kinase catalytic subunit gamma 2","Uniprot":["P15735"],"Chromosome":"16","Position":"30748293-30761176","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Carbohydrate metabolism","Glycogen metabolism"],"Molecular function":["Calmodulin-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Glycogen storage disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"testis":"130.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"397.0","Late spermatids":"1576.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065618","HPA068751"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA065618":"AB_2685520","HPA068751":"AB_2686025"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.90e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.92e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.90e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.02e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.0","Tissue RNA - adrenal gland [nTPM]":"15.8","Tissue RNA - amygdala [nTPM]":"17.5","Tissue RNA - appendix [nTPM]":"11.5","Tissue RNA - basal ganglia [nTPM]":"16.9","Tissue RNA - bone marrow [nTPM]":"30.0","Tissue RNA - breast [nTPM]":"9.9","Tissue RNA - cerebellum [nTPM]":"17.1","Tissue RNA - cerebral cortex [nTPM]":"18.7","Tissue RNA - cervix [nTPM]":"10.0","Tissue RNA - choroid plexus [nTPM]":"15.9","Tissue RNA - colon [nTPM]":"12.9","Tissue RNA - duodenum [nTPM]":"11.0","Tissue RNA - endometrium 1 [nTPM]":"10.1","Tissue RNA - epididymis [nTPM]":"9.5","Tissue RNA - esophagus [nTPM]":"10.2","Tissue RNA - fallopian tube [nTPM]":"11.7","Tissue RNA - gallbladder [nTPM]":"8.2","Tissue RNA - heart muscle [nTPM]":"12.1","Tissue RNA - hippocampal formation [nTPM]":"18.9","Tissue RNA - hypothalamus [nTPM]":"16.4","Tissue RNA - kidney [nTPM]":"14.7","Tissue RNA - liver [nTPM]":"19.1","Tissue RNA - lung [nTPM]":"10.0","Tissue RNA - lymph node [nTPM]":"12.5","Tissue RNA - medulla oblongata [nTPM]":"17.7","Tissue RNA - midbrain [nTPM]":"17.2","Tissue RNA - ovary [nTPM]":"8.3","Tissue RNA - pancreas [nTPM]":"9.7","Tissue RNA - parathyroid gland [nTPM]":"18.9","Tissue RNA - pituitary gland [nTPM]":"15.9","Tissue RNA - placenta [nTPM]":"7.8","Tissue RNA - pons [nTPM]":"18.8","Tissue RNA - prostate [nTPM]":"14.7","Tissue RNA - rectum [nTPM]":"12.0","Tissue RNA - retina [nTPM]":"8.9","Tissue RNA - salivary gland [nTPM]":"11.5","Tissue RNA - seminal vesicle [nTPM]":"12.0","Tissue RNA - skeletal muscle [nTPM]":"13.2","Tissue RNA - skin 1 [nTPM]":"14.6","Tissue RNA - small intestine [nTPM]":"12.0","Tissue RNA - smooth muscle [nTPM]":"9.9","Tissue RNA - spinal cord [nTPM]":"16.0","Tissue RNA - spleen [nTPM]":"12.9","Tissue RNA - stomach 1 [nTPM]":"13.8","Tissue RNA - testis [nTPM]":"130.1","Tissue RNA - thalamus [nTPM]":"17.5","Tissue RNA - thymus [nTPM]":"11.6","Tissue RNA - thyroid gland [nTPM]":"13.6","Tissue RNA - tongue [nTPM]":"8.8","Tissue RNA - tonsil [nTPM]":"12.7","Tissue RNA - urinary bladder [nTPM]":"10.1","Tissue RNA - vagina [nTPM]":"9.2","Tissue RNA - white matter [nTPM]":"16.2","Cell RNA - A-431 [nTPM]":"24.7","Cell RNA - A549 [nTPM]":"16.3","Cell RNA - AF22 [nTPM]":"13.1","Cell RNA - AN3-CA [nTPM]":"16.2","Cell RNA - ASC diff [nTPM]":"11.8","Cell RNA - ASC TERT1 [nTPM]":"9.4","Cell RNA - BEWO [nTPM]":"29.8","Cell RNA - BJ [nTPM]":"17.2","Cell RNA - BJ hTERT+ [nTPM]":"24.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"22.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"25.1","Cell RNA - CACO-2 [nTPM]":"13.5","Cell RNA - CAPAN-2 [nTPM]":"12.6","Cell RNA - Daudi [nTPM]":"21.0","Cell RNA - EFO-21 [nTPM]":"19.3","Cell RNA - fHDF\/TERT166 [nTPM]":"17.1","Cell RNA - GAMG [nTPM]":"11.5","Cell RNA - HaCaT [nTPM]":"24.0","Cell RNA - HAP1 [nTPM]":"13.5","Cell RNA - HBEC3-KT [nTPM]":"21.5","Cell RNA - HBF TERT88 [nTPM]":"17.6","Cell RNA - HDLM-2 [nTPM]":"11.4","Cell RNA - HEK 293 [nTPM]":"38.2","Cell RNA - HEL [nTPM]":"11.9","Cell RNA - HeLa [nTPM]":"28.8","Cell RNA - Hep G2 [nTPM]":"38.7","Cell RNA - HHSteC [nTPM]":"18.1","Cell RNA - HL-60 [nTPM]":"18.1","Cell RNA - HMC-1 [nTPM]":"16.9","Cell RNA - HSkMC [nTPM]":"12.9","Cell RNA - hTCEpi [nTPM]":"11.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.4","Cell RNA - hTERT-HME1 [nTPM]":"9.9","Cell RNA - hTERT-RPE1 [nTPM]":"10.7","Cell RNA - HUVEC TERT2 [nTPM]":"22.8","Cell RNA - JURKAT [nTPM]":"15.3","Cell RNA - K-562 [nTPM]":"16.1","Cell RNA - Karpas-707 [nTPM]":"11.7","Cell RNA - LHCN-M2 [nTPM]":"16.3","Cell RNA - MCF7 [nTPM]":"55.5","Cell RNA - MOLT-4 [nTPM]":"22.3","Cell RNA - NB-4 [nTPM]":"27.1","Cell RNA - NTERA-2 [nTPM]":"18.0","Cell RNA - OE19 [nTPM]":"17.6","Cell RNA - PC-3 [nTPM]":"18.0","Cell RNA - REH [nTPM]":"29.4","Cell RNA - RH-30 [nTPM]":"20.0","Cell RNA - RPMI-8226 [nTPM]":"28.2","Cell RNA - RPTEC TERT1 [nTPM]":"25.7","Cell RNA - RT4 [nTPM]":"27.2","Cell RNA - SCLC-21H [nTPM]":"17.5","Cell RNA - SH-SY5Y [nTPM]":"11.9","Cell RNA - SiHa [nTPM]":"13.5","Cell RNA - SK-BR-3 [nTPM]":"38.1","Cell RNA - SK-MEL-30 [nTPM]":"16.6","Cell RNA - SuSa [nTPM]":"11.8","Cell RNA - T-47d [nTPM]":"30.1","Cell RNA - THP-1 [nTPM]":"15.5","Cell RNA - TIME [nTPM]":"13.6","Cell RNA - U-138 MG [nTPM]":"14.4","Cell RNA - U-2 OS [nTPM]":"15.1","Cell RNA - U-2197 [nTPM]":"17.2","Cell RNA - U-251 MG [nTPM]":"16.0","Cell RNA - U-266\/70 [nTPM]":"24.1","Cell RNA - U-266\/84 [nTPM]":"14.4","Cell RNA - U-698 [nTPM]":"14.8","Cell RNA - U-87 MG [nTPM]":"27.3","Cell RNA - U-937 [nTPM]":"35.2","Cell RNA - WM-115 [nTPM]":"11.4","Blood RNA - basophil [nTPM]":"44.0","Blood RNA - classical monocyte [nTPM]":"55.8","Blood RNA - eosinophil [nTPM]":"114.9","Blood RNA - gdT-cell [nTPM]":"37.8","Blood RNA - intermediate monocyte [nTPM]":"56.5","Blood RNA - MAIT T-cell [nTPM]":"30.9","Blood RNA - memory B-cell [nTPM]":"21.1","Blood RNA - memory CD4 T-cell [nTPM]":"27.1","Blood RNA - memory CD8 T-cell [nTPM]":"38.8","Blood RNA - myeloid DC [nTPM]":"52.0","Blood RNA - naive B-cell [nTPM]":"21.5","Blood RNA - naive CD4 T-cell [nTPM]":"24.2","Blood RNA - naive CD8 T-cell [nTPM]":"27.7","Blood RNA - neutrophil [nTPM]":"44.7","Blood RNA - NK-cell [nTPM]":"63.8","Blood RNA - non-classical monocyte [nTPM]":"42.3","Blood RNA - plasmacytoid DC [nTPM]":"46.1","Blood RNA - T-reg [nTPM]":"43.3","Blood RNA - total PBMC [nTPM]":"49.0","Brain RNA - amygdala [nTPM]":"17.5","Brain RNA - basal ganglia [nTPM]":"16.9","Brain RNA - cerebellum [nTPM]":"17.1","Brain RNA - cerebral cortex [nTPM]":"18.7","Brain RNA - hippocampal formation [nTPM]":"18.9","Brain RNA - hypothalamus [nTPM]":"16.4","Brain RNA - medulla oblongata [nTPM]":"17.7","Brain RNA - midbrain [nTPM]":"17.2","Brain RNA - pons [nTPM]":"18.8","Brain RNA - spinal cord [nTPM]":"16.0","Brain RNA - thalamus [nTPM]":"17.5","Brain RNA - white matter [nTPM]":"16.2","Single Cell Type RNA - Adipocytes [nTPM]":"10.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.7","Single Cell Type RNA - Astrocytes [nTPM]":"13.7","Single Cell Type RNA - B-cells [nTPM]":"18.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"21.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"28.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.8","Single Cell Type RNA - Bipolar cells [nTPM]":"8.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"32.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"29.6","Single Cell Type RNA - dendritic cells [nTPM]":"32.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"32.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"27.4","Single Cell Type RNA - Ductal cells [nTPM]":"11.9","Single Cell Type RNA - Early spermatids [nTPM]":"397.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"35.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.0","Single Cell Type RNA - Endothelial cells [nTPM]":"10.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.3","Single Cell Type RNA - Erythroid cells [nTPM]":"20.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"24.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"41.5","Single Cell Type RNA - Fibroblasts [nTPM]":"11.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"44.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"38.8","Single Cell Type RNA - granulocytes [nTPM]":"13.3","Single Cell Type RNA - Granulosa cells [nTPM]":"16.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.4","Single Cell Type RNA - Hepatocytes [nTPM]":"24.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.2","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.4","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"19.1","Single Cell Type RNA - Langerhans cells [nTPM]":"27.2","Single Cell Type RNA - Late spermatids [nTPM]":"1576.6","Single Cell Type RNA - Leydig cells [nTPM]":"17.4","Single Cell Type RNA - Macrophages [nTPM]":"26.4","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"40.3","Single Cell Type RNA - Muller glia cells [nTPM]":"13.7","Single Cell Type RNA - NK-cells [nTPM]":"39.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.6","Single Cell Type RNA - Paneth cells [nTPM]":"18.5","Single Cell Type RNA - Peritubular cells [nTPM]":"23.3","Single Cell Type RNA - Plasma cells [nTPM]":"20.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"31.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"27.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"47.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.8","Single Cell Type RNA - Spermatocytes [nTPM]":"180.5","Single Cell Type RNA - Spermatogonia [nTPM]":"22.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"23.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"75.5","Single Cell Type RNA - T-cells [nTPM]":"25.9","Single Cell Type RNA - Theca cells [nTPM]":"20.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"27.0","Single Cell Type RNA - Urothelial cells [nTPM]":"16.9"},{"Gene":"PHYH","Gene synonym":["PAHX","PHYH1","RD"],"Ensembl":"ENSG00000107537","Gene description":"Phytanoyl-CoA 2-hydroxylase","Uniprot":["O14832"],"Chromosome":"10","Position":"13277796-13302412","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Dioxygenase","Oxidoreductase"],"Disease involvement":["Cataract","Deafness","Disease variant","Ichthyosis","Peroxisome biogenesis disorder","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"667.8","skeletal muscle":"483.6","tongue":"412.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"258.6","Proximal tubular cells":"414.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"78.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"110.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007598","HPA011796"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA007598":"AB_1855334","HPA011796":"AB_1855335"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.28e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Tissue RNA - adipose tissue [nTPM]":"57.9","Tissue RNA - adrenal gland [nTPM]":"66.5","Tissue RNA - amygdala [nTPM]":"22.9","Tissue RNA - appendix [nTPM]":"9.5","Tissue RNA - basal ganglia [nTPM]":"23.7","Tissue RNA - bone marrow [nTPM]":"8.2","Tissue RNA - breast [nTPM]":"32.2","Tissue RNA - cerebellum [nTPM]":"23.5","Tissue RNA - cerebral cortex [nTPM]":"28.3","Tissue RNA - cervix [nTPM]":"28.8","Tissue RNA - choroid plexus [nTPM]":"31.7","Tissue RNA - colon [nTPM]":"46.5","Tissue RNA - duodenum [nTPM]":"58.7","Tissue RNA - endometrium 1 [nTPM]":"22.1","Tissue RNA - epididymis [nTPM]":"16.7","Tissue RNA - esophagus [nTPM]":"22.9","Tissue RNA - fallopian tube [nTPM]":"16.7","Tissue RNA - gallbladder [nTPM]":"28.2","Tissue RNA - heart muscle [nTPM]":"126.5","Tissue RNA - hippocampal formation [nTPM]":"21.7","Tissue RNA - hypothalamus [nTPM]":"24.1","Tissue RNA - kidney [nTPM]":"191.4","Tissue RNA - liver [nTPM]":"667.8","Tissue RNA - lung [nTPM]":"17.3","Tissue RNA - lymph node [nTPM]":"7.5","Tissue RNA - medulla oblongata [nTPM]":"21.6","Tissue RNA - midbrain [nTPM]":"24.4","Tissue RNA - ovary [nTPM]":"36.8","Tissue RNA - pancreas [nTPM]":"48.2","Tissue RNA - parathyroid gland [nTPM]":"56.7","Tissue RNA - pituitary gland [nTPM]":"20.9","Tissue RNA - placenta [nTPM]":"19.3","Tissue RNA - pons [nTPM]":"22.8","Tissue RNA - prostate [nTPM]":"22.5","Tissue RNA - rectum [nTPM]":"37.2","Tissue RNA - retina [nTPM]":"28.2","Tissue RNA - salivary gland [nTPM]":"33.7","Tissue RNA - seminal vesicle [nTPM]":"25.4","Tissue RNA - skeletal muscle [nTPM]":"483.6","Tissue RNA - skin 1 [nTPM]":"17.5","Tissue RNA - small intestine [nTPM]":"55.8","Tissue RNA - smooth muscle [nTPM]":"23.2","Tissue RNA - spinal cord [nTPM]":"22.7","Tissue RNA - spleen [nTPM]":"12.8","Tissue RNA - stomach 1 [nTPM]":"44.2","Tissue RNA - testis [nTPM]":"15.1","Tissue RNA - thalamus [nTPM]":"26.0","Tissue RNA - thymus [nTPM]":"5.6","Tissue RNA - thyroid gland [nTPM]":"56.0","Tissue RNA - tongue [nTPM]":"412.7","Tissue RNA - tonsil [nTPM]":"5.4","Tissue RNA - urinary bladder [nTPM]":"27.0","Tissue RNA - vagina [nTPM]":"14.8","Tissue RNA - white matter [nTPM]":"23.6","Cell RNA - A-431 [nTPM]":"17.2","Cell RNA - A549 [nTPM]":"35.2","Cell RNA - AF22 [nTPM]":"15.6","Cell RNA - AN3-CA [nTPM]":"22.5","Cell RNA - ASC diff [nTPM]":"110.7","Cell RNA - ASC TERT1 [nTPM]":"69.9","Cell RNA - BEWO [nTPM]":"12.4","Cell RNA - BJ [nTPM]":"17.2","Cell RNA - BJ hTERT+ [nTPM]":"23.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.1","Cell RNA - CACO-2 [nTPM]":"9.1","Cell RNA - CAPAN-2 [nTPM]":"30.3","Cell RNA - Daudi [nTPM]":"0.9","Cell RNA - EFO-21 [nTPM]":"12.9","Cell RNA - fHDF\/TERT166 [nTPM]":"29.0","Cell RNA - GAMG [nTPM]":"47.0","Cell RNA - HaCaT [nTPM]":"7.8","Cell RNA - HAP1 [nTPM]":"20.5","Cell RNA - HBEC3-KT [nTPM]":"20.2","Cell RNA - HBF TERT88 [nTPM]":"11.8","Cell RNA - HDLM-2 [nTPM]":"41.4","Cell RNA - HEK 293 [nTPM]":"10.7","Cell RNA - HEL [nTPM]":"14.9","Cell RNA - HeLa [nTPM]":"9.3","Cell RNA - Hep G2 [nTPM]":"36.6","Cell RNA - HHSteC [nTPM]":"54.8","Cell RNA - HL-60 [nTPM]":"2.5","Cell RNA - HMC-1 [nTPM]":"26.8","Cell RNA - HSkMC [nTPM]":"50.3","Cell RNA - hTCEpi [nTPM]":"28.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.0","Cell RNA - hTERT-HME1 [nTPM]":"8.4","Cell RNA - hTERT-RPE1 [nTPM]":"22.7","Cell RNA - HUVEC TERT2 [nTPM]":"18.7","Cell RNA - JURKAT [nTPM]":"16.8","Cell RNA - K-562 [nTPM]":"8.4","Cell RNA - Karpas-707 [nTPM]":"32.2","Cell RNA - LHCN-M2 [nTPM]":"45.5","Cell RNA - MCF7 [nTPM]":"16.3","Cell RNA - MOLT-4 [nTPM]":"9.2","Cell RNA - NB-4 [nTPM]":"12.1","Cell RNA - NTERA-2 [nTPM]":"14.4","Cell RNA - OE19 [nTPM]":"49.4","Cell RNA - PC-3 [nTPM]":"12.6","Cell RNA - REH [nTPM]":"15.7","Cell RNA - RH-30 [nTPM]":"24.1","Cell RNA - RPMI-8226 [nTPM]":"5.8","Cell RNA - RPTEC TERT1 [nTPM]":"40.6","Cell RNA - RT4 [nTPM]":"21.9","Cell RNA - SCLC-21H [nTPM]":"5.3","Cell RNA - SH-SY5Y [nTPM]":"16.8","Cell RNA - SiHa [nTPM]":"64.8","Cell RNA - SK-BR-3 [nTPM]":"1.4","Cell RNA - SK-MEL-30 [nTPM]":"32.9","Cell RNA - SuSa [nTPM]":"12.5","Cell RNA - T-47d [nTPM]":"64.8","Cell RNA - THP-1 [nTPM]":"44.2","Cell RNA - TIME [nTPM]":"6.4","Cell RNA - U-138 MG [nTPM]":"29.5","Cell RNA - U-2 OS [nTPM]":"10.6","Cell RNA - U-2197 [nTPM]":"36.4","Cell RNA - U-251 MG [nTPM]":"11.8","Cell RNA - U-266\/70 [nTPM]":"36.6","Cell RNA - U-266\/84 [nTPM]":"26.3","Cell RNA - U-698 [nTPM]":"3.3","Cell RNA - U-87 MG [nTPM]":"38.3","Cell RNA - U-937 [nTPM]":"18.9","Cell RNA - WM-115 [nTPM]":"11.6","Blood RNA - basophil [nTPM]":"16.3","Blood RNA - classical monocyte [nTPM]":"18.7","Blood RNA - eosinophil [nTPM]":"8.2","Blood RNA - gdT-cell [nTPM]":"8.0","Blood RNA - intermediate monocyte [nTPM]":"14.2","Blood RNA - MAIT T-cell [nTPM]":"17.6","Blood RNA - memory B-cell [nTPM]":"11.0","Blood RNA - memory CD4 T-cell [nTPM]":"9.9","Blood RNA - memory CD8 T-cell [nTPM]":"10.4","Blood RNA - myeloid DC [nTPM]":"15.8","Blood RNA - naive B-cell [nTPM]":"5.6","Blood RNA - naive CD4 T-cell [nTPM]":"12.5","Blood RNA - naive CD8 T-cell [nTPM]":"12.7","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"4.4","Blood RNA - non-classical monocyte [nTPM]":"11.2","Blood RNA - plasmacytoid DC [nTPM]":"14.4","Blood RNA - T-reg [nTPM]":"10.5","Blood RNA - total PBMC [nTPM]":"12.3","Brain RNA - amygdala [nTPM]":"22.9","Brain RNA - basal ganglia [nTPM]":"23.7","Brain RNA - cerebellum [nTPM]":"23.5","Brain RNA - cerebral cortex [nTPM]":"28.3","Brain RNA - hippocampal formation [nTPM]":"21.7","Brain RNA - hypothalamus [nTPM]":"24.1","Brain RNA - medulla oblongata [nTPM]":"21.6","Brain RNA - midbrain [nTPM]":"24.4","Brain RNA - pons [nTPM]":"22.8","Brain RNA - spinal cord [nTPM]":"22.7","Brain RNA - thalamus [nTPM]":"26.0","Brain RNA - white matter [nTPM]":"23.6","Single Cell Type RNA - Adipocytes [nTPM]":"53.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.2","Single Cell Type RNA - Astrocytes [nTPM]":"8.5","Single Cell Type RNA - B-cells [nTPM]":"14.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"19.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"47.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"258.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"77.2","Single Cell Type RNA - Club cells [nTPM]":"19.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"35.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"137.8","Single Cell Type RNA - dendritic cells [nTPM]":"20.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"72.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"144.8","Single Cell Type RNA - Ductal cells [nTPM]":"40.6","Single Cell Type RNA - Early spermatids [nTPM]":"33.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.0","Single Cell Type RNA - Endothelial cells [nTPM]":"29.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"31.8","Single Cell Type RNA - Erythroid cells [nTPM]":"15.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"34.3","Single Cell Type RNA - Fibroblasts [nTPM]":"41.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"41.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.8","Single Cell Type RNA - granulocytes [nTPM]":"30.4","Single Cell Type RNA - Granulosa cells [nTPM]":"28.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.0","Single Cell Type RNA - Hepatocytes [nTPM]":"145.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"55.4","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"57.4","Single Cell Type RNA - Ionocytes [nTPM]":"46.8","Single Cell Type RNA - Kupffer cells [nTPM]":"21.0","Single Cell Type RNA - Langerhans cells [nTPM]":"22.0","Single Cell Type RNA - Late spermatids [nTPM]":"45.4","Single Cell Type RNA - Leydig cells [nTPM]":"25.4","Single Cell Type RNA - Macrophages [nTPM]":"25.3","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"10.3","Single Cell Type RNA - Muller glia cells [nTPM]":"69.3","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.7","Single Cell Type RNA - Paneth cells [nTPM]":"46.0","Single Cell Type RNA - Peritubular cells [nTPM]":"37.6","Single Cell Type RNA - Plasma cells [nTPM]":"15.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"141.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"414.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"41.8","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"37.5","Single Cell Type RNA - Spermatocytes [nTPM]":"12.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"83.9","Single Cell Type RNA - T-cells [nTPM]":"25.2","Single Cell Type RNA - Theca cells [nTPM]":"103.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"46.9","Single Cell Type RNA - Urothelial cells [nTPM]":"18.1"},{"Gene":"PHYKPL","Gene synonym":["AGXT2L2","MGC15875"],"Ensembl":"ENSG00000175309","Gene description":"5-phosphohydroxy-L-lysine phospho-lyase","Uniprot":["Q8IUZ5"],"Chromosome":"5","Position":"178208471-178232802","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Lyase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036461","HPA063608"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"160000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA036461":"AB_10670717","HPA063608":"AB_2685059"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.82e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-3"},"Tissue RNA - adipose tissue [nTPM]":"23.2","Tissue RNA - adrenal gland [nTPM]":"10.6","Tissue RNA - amygdala [nTPM]":"7.4","Tissue RNA - appendix [nTPM]":"16.4","Tissue RNA - basal ganglia [nTPM]":"8.2","Tissue RNA - bone marrow [nTPM]":"14.9","Tissue RNA - breast [nTPM]":"14.0","Tissue RNA - cerebellum [nTPM]":"6.8","Tissue RNA - cerebral cortex [nTPM]":"8.6","Tissue RNA - cervix [nTPM]":"12.3","Tissue RNA - choroid plexus [nTPM]":"8.3","Tissue RNA - colon [nTPM]":"23.9","Tissue RNA - duodenum [nTPM]":"20.7","Tissue RNA - endometrium 1 [nTPM]":"14.3","Tissue RNA - epididymis [nTPM]":"15.8","Tissue RNA - esophagus [nTPM]":"11.1","Tissue RNA - fallopian tube [nTPM]":"13.9","Tissue RNA - gallbladder [nTPM]":"14.4","Tissue RNA - heart muscle [nTPM]":"15.5","Tissue RNA - hippocampal formation [nTPM]":"6.7","Tissue RNA - hypothalamus [nTPM]":"8.3","Tissue RNA - kidney [nTPM]":"17.5","Tissue RNA - liver [nTPM]":"42.2","Tissue RNA - lung [nTPM]":"15.8","Tissue RNA - lymph node [nTPM]":"24.5","Tissue RNA - medulla oblongata [nTPM]":"11.4","Tissue RNA - midbrain [nTPM]":"8.3","Tissue RNA - ovary [nTPM]":"12.5","Tissue RNA - pancreas [nTPM]":"15.6","Tissue RNA - parathyroid gland [nTPM]":"13.7","Tissue RNA - pituitary gland [nTPM]":"5.2","Tissue RNA - placenta [nTPM]":"16.3","Tissue RNA - pons [nTPM]":"10.0","Tissue RNA - prostate [nTPM]":"13.7","Tissue RNA - rectum [nTPM]":"30.8","Tissue RNA - retina [nTPM]":"3.4","Tissue RNA - salivary gland [nTPM]":"13.8","Tissue RNA - seminal vesicle [nTPM]":"12.0","Tissue RNA - skeletal muscle [nTPM]":"19.6","Tissue RNA - skin 1 [nTPM]":"10.7","Tissue RNA - small intestine [nTPM]":"24.8","Tissue RNA - smooth muscle [nTPM]":"18.5","Tissue RNA - spinal cord [nTPM]":"7.6","Tissue RNA - spleen [nTPM]":"17.2","Tissue RNA - stomach 1 [nTPM]":"15.5","Tissue RNA - testis [nTPM]":"5.9","Tissue RNA - thalamus [nTPM]":"9.5","Tissue RNA - thymus [nTPM]":"25.1","Tissue RNA - thyroid gland [nTPM]":"19.7","Tissue RNA - tongue [nTPM]":"18.7","Tissue RNA - tonsil [nTPM]":"23.6","Tissue RNA - urinary bladder [nTPM]":"13.7","Tissue RNA - vagina [nTPM]":"9.6","Tissue RNA - white matter [nTPM]":"11.7","Cell RNA - A-431 [nTPM]":"9.6","Cell RNA - A549 [nTPM]":"3.8","Cell RNA - AF22 [nTPM]":"9.0","Cell RNA - AN3-CA [nTPM]":"3.6","Cell RNA - ASC diff [nTPM]":"21.6","Cell RNA - ASC TERT1 [nTPM]":"17.4","Cell RNA - BEWO [nTPM]":"13.9","Cell RNA - BJ [nTPM]":"5.6","Cell RNA - BJ hTERT+ [nTPM]":"6.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.8","Cell RNA - CACO-2 [nTPM]":"9.7","Cell RNA - CAPAN-2 [nTPM]":"11.7","Cell RNA - Daudi [nTPM]":"13.0","Cell RNA - EFO-21 [nTPM]":"18.4","Cell RNA - fHDF\/TERT166 [nTPM]":"17.6","Cell RNA - GAMG [nTPM]":"9.7","Cell RNA - HaCaT [nTPM]":"6.2","Cell RNA - HAP1 [nTPM]":"7.7","Cell RNA - HBEC3-KT [nTPM]":"14.3","Cell RNA - HBF TERT88 [nTPM]":"8.5","Cell RNA - HDLM-2 [nTPM]":"24.0","Cell RNA - HEK 293 [nTPM]":"8.7","Cell RNA - HEL [nTPM]":"15.6","Cell RNA - HeLa [nTPM]":"18.0","Cell RNA - Hep G2 [nTPM]":"7.1","Cell RNA - HHSteC [nTPM]":"35.1","Cell RNA - HL-60 [nTPM]":"9.2","Cell RNA - HMC-1 [nTPM]":"11.4","Cell RNA - HSkMC [nTPM]":"19.6","Cell RNA - hTCEpi [nTPM]":"15.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.3","Cell RNA - hTERT-HME1 [nTPM]":"22.4","Cell RNA - hTERT-RPE1 [nTPM]":"14.9","Cell RNA - HUVEC TERT2 [nTPM]":"24.9","Cell RNA - JURKAT [nTPM]":"18.6","Cell RNA - K-562 [nTPM]":"11.8","Cell RNA - Karpas-707 [nTPM]":"26.7","Cell RNA - LHCN-M2 [nTPM]":"11.3","Cell RNA - MCF7 [nTPM]":"13.1","Cell RNA - MOLT-4 [nTPM]":"13.1","Cell RNA - NB-4 [nTPM]":"5.5","Cell RNA - NTERA-2 [nTPM]":"1.9","Cell RNA - OE19 [nTPM]":"11.5","Cell RNA - PC-3 [nTPM]":"12.4","Cell RNA - REH [nTPM]":"9.1","Cell RNA - RH-30 [nTPM]":"4.3","Cell RNA - RPMI-8226 [nTPM]":"25.0","Cell RNA - RPTEC TERT1 [nTPM]":"13.4","Cell RNA - RT4 [nTPM]":"8.3","Cell RNA - SCLC-21H [nTPM]":"5.7","Cell RNA - SH-SY5Y [nTPM]":"5.4","Cell RNA - SiHa [nTPM]":"9.2","Cell RNA - SK-BR-3 [nTPM]":"5.2","Cell RNA - SK-MEL-30 [nTPM]":"9.4","Cell RNA - SuSa [nTPM]":"10.2","Cell RNA - T-47d [nTPM]":"5.5","Cell RNA - THP-1 [nTPM]":"7.4","Cell RNA - TIME [nTPM]":"9.9","Cell RNA - U-138 MG [nTPM]":"7.8","Cell RNA - U-2 OS [nTPM]":"7.0","Cell RNA - U-2197 [nTPM]":"5.1","Cell RNA - U-251 MG [nTPM]":"6.2","Cell RNA - U-266\/70 [nTPM]":"18.8","Cell RNA - U-266\/84 [nTPM]":"5.5","Cell RNA - U-698 [nTPM]":"7.2","Cell RNA - U-87 MG [nTPM]":"2.2","Cell RNA - U-937 [nTPM]":"9.2","Cell RNA - WM-115 [nTPM]":"5.2","Blood RNA - basophil [nTPM]":"16.7","Blood RNA - classical monocyte [nTPM]":"41.7","Blood RNA - eosinophil [nTPM]":"36.9","Blood RNA - gdT-cell [nTPM]":"20.3","Blood RNA - intermediate monocyte [nTPM]":"46.8","Blood RNA - MAIT T-cell [nTPM]":"20.4","Blood RNA - memory B-cell [nTPM]":"28.4","Blood RNA - memory CD4 T-cell [nTPM]":"22.2","Blood RNA - memory CD8 T-cell [nTPM]":"22.9","Blood RNA - myeloid DC [nTPM]":"53.4","Blood RNA - naive B-cell [nTPM]":"26.3","Blood RNA - naive CD4 T-cell [nTPM]":"27.3","Blood RNA - naive CD8 T-cell [nTPM]":"22.2","Blood RNA - neutrophil [nTPM]":"9.2","Blood RNA - NK-cell [nTPM]":"23.7","Blood RNA - non-classical monocyte [nTPM]":"47.2","Blood RNA - plasmacytoid DC [nTPM]":"70.9","Blood RNA - T-reg [nTPM]":"28.6","Blood RNA - total PBMC [nTPM]":"33.2","Brain RNA - amygdala [nTPM]":"7.4","Brain RNA - basal ganglia [nTPM]":"8.2","Brain RNA - cerebellum [nTPM]":"6.8","Brain RNA - cerebral cortex [nTPM]":"8.6","Brain RNA - hippocampal formation [nTPM]":"6.7","Brain RNA - hypothalamus [nTPM]":"8.3","Brain RNA - medulla oblongata [nTPM]":"11.4","Brain RNA - midbrain [nTPM]":"8.3","Brain RNA - pons [nTPM]":"10.0","Brain RNA - spinal cord [nTPM]":"7.6","Brain RNA - thalamus [nTPM]":"9.5","Brain RNA - white matter [nTPM]":"11.7","Single Cell Type RNA - Adipocytes [nTPM]":"23.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.3","Single Cell Type RNA - Astrocytes [nTPM]":"31.6","Single Cell Type RNA - B-cells [nTPM]":"63.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"43.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.0","Single Cell Type RNA - Bipolar cells [nTPM]":"21.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"37.1","Single Cell Type RNA - Club cells [nTPM]":"13.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.4","Single Cell Type RNA - dendritic cells [nTPM]":"72.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"96.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"24.6","Single Cell Type RNA - Early spermatids [nTPM]":"21.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"27.7","Single Cell Type RNA - Endothelial cells [nTPM]":"26.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.2","Single Cell Type RNA - Erythroid cells [nTPM]":"30.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"20.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.2","Single Cell Type RNA - Fibroblasts [nTPM]":"33.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"76.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.8","Single Cell Type RNA - granulocytes [nTPM]":"12.7","Single Cell Type RNA - Granulosa cells [nTPM]":"38.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"31.1","Single Cell Type RNA - Hepatocytes [nTPM]":"30.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"31.7","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"40.8","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"37.1","Single Cell Type RNA - Langerhans cells [nTPM]":"22.9","Single Cell Type RNA - Late spermatids [nTPM]":"55.3","Single Cell Type RNA - Leydig cells [nTPM]":"42.6","Single Cell Type RNA - Macrophages [nTPM]":"43.3","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"36.5","Single Cell Type RNA - monocytes [nTPM]":"61.1","Single Cell Type RNA - Muller glia cells [nTPM]":"25.0","Single Cell Type RNA - NK-cells [nTPM]":"70.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"29.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"45.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.1","Single Cell Type RNA - Paneth cells [nTPM]":"64.5","Single Cell Type RNA - Peritubular cells [nTPM]":"25.2","Single Cell Type RNA - Plasma cells [nTPM]":"51.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"119.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"43.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"26.4","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"34.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.6","Single Cell Type RNA - Spermatocytes [nTPM]":"37.2","Single Cell Type RNA - Spermatogonia [nTPM]":"25.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.0","Single Cell Type RNA - T-cells [nTPM]":"58.9","Single Cell Type RNA - Theca cells [nTPM]":"36.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"39.2","Single Cell Type RNA - Urothelial cells [nTPM]":"36.6"},{"Gene":"PI4KA","Gene synonym":["PI4K-ALPHA","pi4K230","PIK4CA"],"Ensembl":"ENSG00000241973","Gene description":"Phosphatidylinositol 4-kinase alpha","Uniprot":["P42356"],"Chromosome":"22","Position":"20707691-20859417","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"209.1","Inhibitory neurons":"127.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"K-562":"130.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009092","HPA075515"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB009092":"AB_2164033","HPA075515":"AB_2686753"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.24e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.22e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Tissue RNA - adipose tissue [nTPM]":"18.8","Tissue RNA - adrenal gland [nTPM]":"21.6","Tissue RNA - amygdala [nTPM]":"45.2","Tissue RNA - appendix [nTPM]":"19.2","Tissue RNA - basal ganglia [nTPM]":"61.0","Tissue RNA - bone marrow [nTPM]":"24.1","Tissue RNA - breast [nTPM]":"16.8","Tissue RNA - cerebellum [nTPM]":"2.1","Tissue RNA - cerebral cortex [nTPM]":"74.4","Tissue RNA - cervix [nTPM]":"20.4","Tissue RNA - choroid plexus [nTPM]":"9.6","Tissue RNA - colon [nTPM]":"23.7","Tissue RNA - duodenum [nTPM]":"15.8","Tissue RNA - endometrium 1 [nTPM]":"24.2","Tissue RNA - epididymis [nTPM]":"9.9","Tissue RNA - esophagus [nTPM]":"14.3","Tissue RNA - fallopian tube [nTPM]":"19.5","Tissue RNA - gallbladder [nTPM]":"13.5","Tissue RNA - heart muscle [nTPM]":"21.5","Tissue RNA - hippocampal formation [nTPM]":"65.3","Tissue RNA - hypothalamus [nTPM]":"9.0","Tissue RNA - kidney [nTPM]":"21.3","Tissue RNA - liver [nTPM]":"25.2","Tissue RNA - lung [nTPM]":"19.1","Tissue RNA - lymph node [nTPM]":"20.5","Tissue RNA - medulla oblongata [nTPM]":"14.6","Tissue RNA - midbrain [nTPM]":"4.8","Tissue RNA - ovary [nTPM]":"21.4","Tissue RNA - pancreas [nTPM]":"18.7","Tissue RNA - parathyroid gland [nTPM]":"34.5","Tissue RNA - pituitary gland [nTPM]":"25.2","Tissue RNA - placenta [nTPM]":"17.9","Tissue RNA - pons [nTPM]":"14.5","Tissue RNA - prostate [nTPM]":"19.5","Tissue RNA - rectum [nTPM]":"14.9","Tissue RNA - retina [nTPM]":"27.7","Tissue RNA - salivary gland [nTPM]":"16.5","Tissue RNA - seminal vesicle [nTPM]":"16.9","Tissue RNA - skeletal muscle [nTPM]":"23.6","Tissue RNA - skin 1 [nTPM]":"15.1","Tissue RNA - small intestine [nTPM]":"22.9","Tissue RNA - smooth muscle [nTPM]":"21.9","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"21.0","Tissue RNA - stomach 1 [nTPM]":"26.0","Tissue RNA - testis [nTPM]":"25.7","Tissue RNA - thalamus [nTPM]":"8.6","Tissue RNA - thymus [nTPM]":"34.3","Tissue RNA - thyroid gland [nTPM]":"18.0","Tissue RNA - tongue [nTPM]":"15.9","Tissue RNA - tonsil [nTPM]":"18.0","Tissue RNA - urinary bladder [nTPM]":"22.2","Tissue RNA - vagina [nTPM]":"16.9","Tissue RNA - white matter [nTPM]":"43.3","Cell RNA - A-431 [nTPM]":"24.5","Cell RNA - A549 [nTPM]":"20.2","Cell RNA - AF22 [nTPM]":"17.4","Cell RNA - AN3-CA [nTPM]":"26.3","Cell RNA - ASC diff [nTPM]":"48.7","Cell RNA - ASC TERT1 [nTPM]":"29.1","Cell RNA - BEWO [nTPM]":"24.9","Cell RNA - BJ [nTPM]":"21.6","Cell RNA - BJ hTERT+ [nTPM]":"32.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"31.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"30.4","Cell RNA - CACO-2 [nTPM]":"15.9","Cell RNA - CAPAN-2 [nTPM]":"10.2","Cell RNA - Daudi [nTPM]":"45.6","Cell RNA - EFO-21 [nTPM]":"12.6","Cell RNA - fHDF\/TERT166 [nTPM]":"43.9","Cell RNA - GAMG [nTPM]":"30.7","Cell RNA - HaCaT [nTPM]":"21.1","Cell RNA - HAP1 [nTPM]":"33.4","Cell RNA - HBEC3-KT [nTPM]":"20.9","Cell RNA - HBF TERT88 [nTPM]":"19.0","Cell RNA - HDLM-2 [nTPM]":"38.9","Cell RNA - HEK 293 [nTPM]":"50.9","Cell RNA - HEL [nTPM]":"47.1","Cell RNA - HeLa [nTPM]":"27.1","Cell RNA - Hep G2 [nTPM]":"18.3","Cell RNA - HHSteC [nTPM]":"24.3","Cell RNA - HL-60 [nTPM]":"47.0","Cell RNA - HMC-1 [nTPM]":"36.1","Cell RNA - HSkMC [nTPM]":"26.2","Cell RNA - hTCEpi [nTPM]":"12.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.7","Cell RNA - hTERT-HME1 [nTPM]":"14.7","Cell RNA - hTERT-RPE1 [nTPM]":"20.4","Cell RNA - HUVEC TERT2 [nTPM]":"25.8","Cell RNA - JURKAT [nTPM]":"13.8","Cell RNA - K-562 [nTPM]":"130.2","Cell RNA - Karpas-707 [nTPM]":"37.6","Cell RNA - LHCN-M2 [nTPM]":"24.6","Cell RNA - MCF7 [nTPM]":"33.8","Cell RNA - MOLT-4 [nTPM]":"41.6","Cell RNA - NB-4 [nTPM]":"16.0","Cell RNA - NTERA-2 [nTPM]":"13.8","Cell RNA - OE19 [nTPM]":"43.4","Cell RNA - PC-3 [nTPM]":"20.6","Cell RNA - REH [nTPM]":"41.1","Cell RNA - RH-30 [nTPM]":"38.1","Cell RNA - RPMI-8226 [nTPM]":"8.5","Cell RNA - RPTEC TERT1 [nTPM]":"17.3","Cell RNA - RT4 [nTPM]":"38.3","Cell RNA - SCLC-21H [nTPM]":"42.6","Cell RNA - SH-SY5Y [nTPM]":"31.0","Cell RNA - SiHa [nTPM]":"28.4","Cell RNA - SK-BR-3 [nTPM]":"32.6","Cell RNA - SK-MEL-30 [nTPM]":"22.6","Cell RNA - SuSa [nTPM]":"24.3","Cell RNA - T-47d [nTPM]":"27.6","Cell RNA - THP-1 [nTPM]":"21.3","Cell RNA - TIME [nTPM]":"26.2","Cell RNA - U-138 MG [nTPM]":"56.4","Cell RNA - U-2 OS [nTPM]":"29.1","Cell RNA - U-2197 [nTPM]":"21.1","Cell RNA - U-251 MG [nTPM]":"18.5","Cell RNA - U-266\/70 [nTPM]":"28.6","Cell RNA - U-266\/84 [nTPM]":"31.3","Cell RNA - U-698 [nTPM]":"35.8","Cell RNA - U-87 MG [nTPM]":"37.4","Cell RNA - U-937 [nTPM]":"33.2","Cell RNA - WM-115 [nTPM]":"24.1","Blood RNA - basophil [nTPM]":"2.1","Blood RNA - classical monocyte [nTPM]":"3.7","Blood RNA - eosinophil [nTPM]":"5.3","Blood RNA - gdT-cell [nTPM]":"3.2","Blood RNA - intermediate monocyte [nTPM]":"3.8","Blood RNA - MAIT T-cell [nTPM]":"3.1","Blood RNA - memory B-cell [nTPM]":"3.4","Blood RNA - memory CD4 T-cell [nTPM]":"3.6","Blood RNA - memory CD8 T-cell [nTPM]":"3.9","Blood RNA - myeloid DC [nTPM]":"2.5","Blood RNA - naive B-cell [nTPM]":"3.4","Blood RNA - naive CD4 T-cell [nTPM]":"3.6","Blood RNA - naive CD8 T-cell [nTPM]":"5.0","Blood RNA - neutrophil [nTPM]":"5.1","Blood RNA - NK-cell [nTPM]":"7.0","Blood RNA - non-classical monocyte [nTPM]":"3.3","Blood RNA - plasmacytoid DC [nTPM]":"8.5","Blood RNA - T-reg [nTPM]":"4.3","Blood RNA - total PBMC [nTPM]":"2.2","Brain RNA - amygdala [nTPM]":"45.2","Brain RNA - basal ganglia [nTPM]":"61.0","Brain RNA - cerebellum [nTPM]":"2.1","Brain RNA - cerebral cortex [nTPM]":"74.4","Brain RNA - hippocampal formation [nTPM]":"65.3","Brain RNA - hypothalamus [nTPM]":"9.0","Brain RNA - medulla oblongata [nTPM]":"14.6","Brain RNA - midbrain [nTPM]":"4.8","Brain RNA - pons [nTPM]":"14.5","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"8.6","Brain RNA - white matter [nTPM]":"43.3","Single Cell Type RNA - Adipocytes [nTPM]":"13.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"30.4","Single Cell Type RNA - Astrocytes [nTPM]":"65.6","Single Cell Type RNA - B-cells [nTPM]":"14.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"35.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"30.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"10.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"47.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"17.8","Single Cell Type RNA - dendritic cells [nTPM]":"21.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"19.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.7","Single Cell Type RNA - Early spermatids [nTPM]":"36.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.9","Single Cell Type RNA - Endothelial cells [nTPM]":"15.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.2","Single Cell Type RNA - Erythroid cells [nTPM]":"12.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"209.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.6","Single Cell Type RNA - Fibroblasts [nTPM]":"15.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"38.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.8","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"13.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.4","Single Cell Type RNA - Hepatocytes [nTPM]":"19.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.1","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"127.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.7","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"21.0","Single Cell Type RNA - Langerhans cells [nTPM]":"12.6","Single Cell Type RNA - Late spermatids [nTPM]":"25.3","Single Cell Type RNA - Leydig cells [nTPM]":"19.9","Single Cell Type RNA - Macrophages [nTPM]":"20.2","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"39.4","Single Cell Type RNA - monocytes [nTPM]":"10.9","Single Cell Type RNA - Muller glia cells [nTPM]":"23.1","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"50.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"88.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.9","Single Cell Type RNA - Paneth cells [nTPM]":"9.7","Single Cell Type RNA - Peritubular cells [nTPM]":"24.0","Single Cell Type RNA - Plasma cells [nTPM]":"15.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"25.4","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.3","Single Cell Type RNA - Spermatocytes [nTPM]":"35.3","Single Cell Type RNA - Spermatogonia [nTPM]":"29.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.0","Single Cell Type RNA - T-cells [nTPM]":"15.3","Single Cell Type RNA - Theca cells [nTPM]":"26.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.3","Single Cell Type RNA - Urothelial cells [nTPM]":"8.9"},{"Gene":"PIEZO1","Gene synonym":["FAM38A","KIAA0233"],"Ensembl":"ENSG00000103335","Gene description":"Piezo type mechanosensitive ion channel component 1","Uniprot":["Q92508"],"Chromosome":"16","Position":"88715338-88785220","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":["Disease variant","Hereditary hemolytic anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"73.7","Pancreatic endocrine cells":"85.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"270.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047185"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047185":"AB_2679973"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.37e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.36e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.78e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.89e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-1"},"Tissue RNA - adipose tissue [nTPM]":"79.0","Tissue RNA - adrenal gland [nTPM]":"26.4","Tissue RNA - amygdala [nTPM]":"15.2","Tissue RNA - appendix [nTPM]":"20.5","Tissue RNA - basal ganglia [nTPM]":"16.0","Tissue RNA - bone marrow [nTPM]":"29.8","Tissue RNA - breast [nTPM]":"65.1","Tissue RNA - cerebellum [nTPM]":"16.5","Tissue RNA - cerebral cortex [nTPM]":"19.0","Tissue RNA - cervix [nTPM]":"30.7","Tissue RNA - choroid plexus [nTPM]":"10.4","Tissue RNA - colon [nTPM]":"86.7","Tissue RNA - duodenum [nTPM]":"7.7","Tissue RNA - endometrium 1 [nTPM]":"40.4","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"48.4","Tissue RNA - fallopian tube [nTPM]":"38.1","Tissue RNA - gallbladder [nTPM]":"9.0","Tissue RNA - heart muscle [nTPM]":"29.4","Tissue RNA - hippocampal formation [nTPM]":"12.9","Tissue RNA - hypothalamus [nTPM]":"13.8","Tissue RNA - kidney [nTPM]":"57.2","Tissue RNA - liver [nTPM]":"48.2","Tissue RNA - lung [nTPM]":"67.2","Tissue RNA - lymph node [nTPM]":"14.8","Tissue RNA - medulla oblongata [nTPM]":"25.0","Tissue RNA - midbrain [nTPM]":"17.6","Tissue RNA - ovary [nTPM]":"15.8","Tissue RNA - pancreas [nTPM]":"21.9","Tissue RNA - parathyroid gland [nTPM]":"5.2","Tissue RNA - pituitary gland [nTPM]":"6.8","Tissue RNA - placenta [nTPM]":"18.6","Tissue RNA - pons [nTPM]":"22.5","Tissue RNA - prostate [nTPM]":"49.4","Tissue RNA - rectum [nTPM]":"4.8","Tissue RNA - retina [nTPM]":"1.7","Tissue RNA - salivary gland [nTPM]":"33.3","Tissue RNA - seminal vesicle [nTPM]":"11.2","Tissue RNA - skeletal muscle [nTPM]":"6.8","Tissue RNA - skin 1 [nTPM]":"48.8","Tissue RNA - small intestine [nTPM]":"41.1","Tissue RNA - smooth muscle [nTPM]":"14.3","Tissue RNA - spinal cord [nTPM]":"17.6","Tissue RNA - spleen [nTPM]":"55.2","Tissue RNA - stomach 1 [nTPM]":"38.0","Tissue RNA - testis [nTPM]":"5.2","Tissue RNA - thalamus [nTPM]":"17.4","Tissue RNA - thymus [nTPM]":"7.2","Tissue RNA - thyroid gland [nTPM]":"32.4","Tissue RNA - tongue [nTPM]":"4.3","Tissue RNA - tonsil [nTPM]":"5.9","Tissue RNA - urinary bladder [nTPM]":"65.3","Tissue RNA - vagina [nTPM]":"40.4","Tissue RNA - white matter [nTPM]":"21.2","Cell RNA - A-431 [nTPM]":"42.0","Cell RNA - A549 [nTPM]":"42.1","Cell RNA - AF22 [nTPM]":"6.5","Cell RNA - AN3-CA [nTPM]":"31.3","Cell RNA - ASC diff [nTPM]":"27.6","Cell RNA - ASC TERT1 [nTPM]":"30.0","Cell RNA - BEWO [nTPM]":"155.2","Cell RNA - BJ [nTPM]":"99.9","Cell RNA - BJ hTERT+ [nTPM]":"43.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"36.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.0","Cell RNA - CACO-2 [nTPM]":"61.3","Cell RNA - CAPAN-2 [nTPM]":"68.5","Cell RNA - Daudi [nTPM]":"34.2","Cell RNA - EFO-21 [nTPM]":"68.2","Cell RNA - fHDF\/TERT166 [nTPM]":"48.4","Cell RNA - GAMG [nTPM]":"18.0","Cell RNA - HaCaT [nTPM]":"88.4","Cell RNA - HAP1 [nTPM]":"13.9","Cell RNA - HBEC3-KT [nTPM]":"36.0","Cell RNA - HBF TERT88 [nTPM]":"7.3","Cell RNA - HDLM-2 [nTPM]":"33.8","Cell RNA - HEK 293 [nTPM]":"56.0","Cell RNA - HEL [nTPM]":"58.3","Cell RNA - HeLa [nTPM]":"77.9","Cell RNA - Hep G2 [nTPM]":"49.4","Cell RNA - HHSteC [nTPM]":"41.6","Cell RNA - HL-60 [nTPM]":"26.4","Cell RNA - HMC-1 [nTPM]":"9.3","Cell RNA - HSkMC [nTPM]":"24.6","Cell RNA - hTCEpi [nTPM]":"19.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"28.3","Cell RNA - hTERT-HME1 [nTPM]":"23.3","Cell RNA - hTERT-RPE1 [nTPM]":"21.3","Cell RNA - HUVEC TERT2 [nTPM]":"43.9","Cell RNA - JURKAT [nTPM]":"56.1","Cell RNA - K-562 [nTPM]":"80.4","Cell RNA - Karpas-707 [nTPM]":"42.8","Cell RNA - LHCN-M2 [nTPM]":"21.2","Cell RNA - MCF7 [nTPM]":"270.1","Cell RNA - MOLT-4 [nTPM]":"32.7","Cell RNA - NB-4 [nTPM]":"91.2","Cell RNA - NTERA-2 [nTPM]":"14.7","Cell RNA - OE19 [nTPM]":"19.7","Cell RNA - PC-3 [nTPM]":"25.7","Cell RNA - REH [nTPM]":"77.7","Cell RNA - RH-30 [nTPM]":"9.3","Cell RNA - RPMI-8226 [nTPM]":"86.9","Cell RNA - RPTEC TERT1 [nTPM]":"16.4","Cell RNA - RT4 [nTPM]":"61.1","Cell RNA - SCLC-21H [nTPM]":"12.8","Cell RNA - SH-SY5Y [nTPM]":"3.4","Cell RNA - SiHa [nTPM]":"130.5","Cell RNA - SK-BR-3 [nTPM]":"68.0","Cell RNA - SK-MEL-30 [nTPM]":"17.8","Cell RNA - SuSa [nTPM]":"6.5","Cell RNA - T-47d [nTPM]":"93.0","Cell RNA - THP-1 [nTPM]":"76.5","Cell RNA - TIME [nTPM]":"120.1","Cell RNA - U-138 MG [nTPM]":"86.0","Cell RNA - U-2 OS [nTPM]":"49.6","Cell RNA - U-2197 [nTPM]":"58.4","Cell RNA - U-251 MG [nTPM]":"51.6","Cell RNA - U-266\/70 [nTPM]":"8.7","Cell RNA - U-266\/84 [nTPM]":"21.1","Cell RNA - U-698 [nTPM]":"21.2","Cell RNA - U-87 MG [nTPM]":"67.9","Cell RNA - U-937 [nTPM]":"46.5","Cell RNA - WM-115 [nTPM]":"52.2","Blood RNA - basophil [nTPM]":"1.8","Blood RNA - classical monocyte [nTPM]":"5.0","Blood RNA - eosinophil [nTPM]":"3.3","Blood RNA - gdT-cell [nTPM]":"8.1","Blood RNA - intermediate monocyte [nTPM]":"9.7","Blood RNA - MAIT T-cell [nTPM]":"7.8","Blood RNA - memory B-cell [nTPM]":"2.3","Blood RNA - memory CD4 T-cell [nTPM]":"6.0","Blood RNA - memory CD8 T-cell [nTPM]":"5.5","Blood RNA - myeloid DC [nTPM]":"9.7","Blood RNA - naive B-cell [nTPM]":"3.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"2.5","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"1.0","Blood RNA - non-classical monocyte [nTPM]":"13.1","Blood RNA - plasmacytoid DC [nTPM]":"1.7","Blood RNA - T-reg [nTPM]":"5.0","Blood RNA - total PBMC [nTPM]":"3.9","Brain RNA - amygdala [nTPM]":"15.2","Brain RNA - basal ganglia [nTPM]":"16.0","Brain RNA - cerebellum [nTPM]":"16.5","Brain RNA - cerebral cortex [nTPM]":"19.0","Brain RNA - hippocampal formation [nTPM]":"12.9","Brain RNA - hypothalamus [nTPM]":"13.8","Brain RNA - medulla oblongata [nTPM]":"25.0","Brain RNA - midbrain [nTPM]":"17.6","Brain RNA - pons [nTPM]":"22.5","Brain RNA - spinal cord [nTPM]":"17.6","Brain RNA - thalamus [nTPM]":"17.4","Brain RNA - white matter [nTPM]":"21.2","Single Cell Type RNA - Adipocytes [nTPM]":"69.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"73.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.8","Single Cell Type RNA - Astrocytes [nTPM]":"27.1","Single Cell Type RNA - B-cells [nTPM]":"14.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"19.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"27.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"2.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"17.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"58.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.7","Single Cell Type RNA - dendritic cells [nTPM]":"16.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"19.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"37.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.4","Single Cell Type RNA - Endothelial cells [nTPM]":"45.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.0","Single Cell Type RNA - Erythroid cells [nTPM]":"12.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"30.5","Single Cell Type RNA - Fibroblasts [nTPM]":"13.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"25.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.9","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"55.3","Single Cell Type RNA - Hepatocytes [nTPM]":"22.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.6","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"29.5","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"16.8","Single Cell Type RNA - Langerhans cells [nTPM]":"19.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"5.6","Single Cell Type RNA - Macrophages [nTPM]":"21.8","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"15.6","Single Cell Type RNA - Muller glia cells [nTPM]":"1.5","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"85.9","Single Cell Type RNA - Paneth cells [nTPM]":"18.0","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"30.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"48.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"2.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.1","Single Cell Type RNA - T-cells [nTPM]":"21.6","Single Cell Type RNA - Theca cells [nTPM]":"5.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.0","Single Cell Type RNA - Urothelial cells [nTPM]":"21.8"},{"Gene":"PIEZO2","Gene synonym":["C18orf30","C18orf58","FAM38B","FAM38B2","FLJ23144","FLJ23403","FLJ34907","HsT748","HsT771"],"Ensembl":"ENSG00000154864","Gene description":"Piezo type mechanosensitive ion channel component 2","Uniprot":["Q9H5I5"],"Chromosome":"18","Position":"10666483-11149569","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sensory transduction","Transport"],"Molecular function":["Ion channel"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"58.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Oligodendrocytes":"399.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"15.1","BJ hTERT+ SV40 Large T+":"16.9","BJ hTERT+ SV40 Large T+ RasG12V":"23.1","HeLa":"38.1","U-266\/70":"23.0","U-698":"16.2"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015986","HPA031974","HPA040616"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA015986":"AB_1848395","HPA031974":"AB_10603675","HPA040616":"AB_2677043"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.57e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.2","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"7.3","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"20.2","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"1.7","Tissue RNA - cerebellum [nTPM]":"14.7","Tissue RNA - cerebral cortex [nTPM]":"14.4","Tissue RNA - cervix [nTPM]":"1.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"3.9","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.6","Tissue RNA - epididymis [nTPM]":"1.6","Tissue RNA - esophagus [nTPM]":"5.1","Tissue RNA - fallopian tube [nTPM]":"1.1","Tissue RNA - gallbladder [nTPM]":"5.3","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"7.9","Tissue RNA - hypothalamus [nTPM]":"8.7","Tissue RNA - kidney [nTPM]":"1.1","Tissue RNA - liver [nTPM]":"4.1","Tissue RNA - lung [nTPM]":"6.6","Tissue RNA - lymph node [nTPM]":"0.9","Tissue RNA - medulla oblongata [nTPM]":"18.2","Tissue RNA - midbrain [nTPM]":"14.4","Tissue RNA - ovary [nTPM]":"0.7","Tissue RNA - pancreas [nTPM]":"1.8","Tissue RNA - parathyroid gland [nTPM]":"0.5","Tissue RNA - pituitary gland [nTPM]":"0.9","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"18.2","Tissue RNA - prostate [nTPM]":"3.0","Tissue RNA - rectum [nTPM]":"1.4","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"2.9","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"1.1","Tissue RNA - small intestine [nTPM]":"1.1","Tissue RNA - smooth muscle [nTPM]":"2.1","Tissue RNA - spinal cord [nTPM]":"8.5","Tissue RNA - spleen [nTPM]":"2.7","Tissue RNA - stomach 1 [nTPM]":"1.6","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"16.8","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"1.5","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.6","Tissue RNA - urinary bladder [nTPM]":"5.3","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"58.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"1.8","Cell RNA - AF22 [nTPM]":"15.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.8","Cell RNA - BJ hTERT+ [nTPM]":"4.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"1.5","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"10.6","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"38.1","Cell RNA - Hep G2 [nTPM]":"8.8","Cell RNA - HHSteC [nTPM]":"5.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.3","Cell RNA - hTERT-HME1 [nTPM]":"1.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"5.2","Cell RNA - JURKAT [nTPM]":"0.6","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"2.7","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"4.5","Cell RNA - OE19 [nTPM]":"6.7","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"7.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"5.3","Cell RNA - SCLC-21H [nTPM]":"12.7","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.8","Cell RNA - SuSa [nTPM]":"6.7","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"4.5","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"5.8","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"23.0","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"16.2","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"10.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"7.3","Brain RNA - basal ganglia [nTPM]":"20.2","Brain RNA - cerebellum [nTPM]":"14.7","Brain RNA - cerebral cortex [nTPM]":"14.4","Brain RNA - hippocampal formation [nTPM]":"7.9","Brain RNA - hypothalamus [nTPM]":"8.7","Brain RNA - medulla oblongata [nTPM]":"18.2","Brain RNA - midbrain [nTPM]":"14.4","Brain RNA - pons [nTPM]":"18.2","Brain RNA - spinal cord [nTPM]":"8.5","Brain RNA - thalamus [nTPM]":"16.8","Brain RNA - white matter [nTPM]":"58.3","Single Cell Type RNA - Adipocytes [nTPM]":"3.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.3","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"31.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"9.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"11.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.2","Single Cell Type RNA - Hepatocytes [nTPM]":"5.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.2","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"11.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"399.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"32.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"PIGA","Gene synonym":["GPI3"],"Ensembl":"ENSG00000165195","Gene description":"Phosphatidylinositol glycan anchor biosynthesis class A","Uniprot":["P37287"],"Chromosome":"X","Position":"15319452-15335554","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["GPI-anchor biosynthesis"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"83.5","Suprabasal keratinocytes":"55.0","Urothelial cells":"62.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"22.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001174"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA001174":"AB_2666220"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.64e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.1","Tissue RNA - adrenal gland [nTPM]":"2.9","Tissue RNA - amygdala [nTPM]":"2.2","Tissue RNA - appendix [nTPM]":"2.9","Tissue RNA - basal ganglia [nTPM]":"2.7","Tissue RNA - bone marrow [nTPM]":"9.2","Tissue RNA - breast [nTPM]":"3.1","Tissue RNA - cerebellum [nTPM]":"2.0","Tissue RNA - cerebral cortex [nTPM]":"3.6","Tissue RNA - cervix [nTPM]":"2.8","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"3.7","Tissue RNA - duodenum [nTPM]":"1.9","Tissue RNA - endometrium 1 [nTPM]":"3.0","Tissue RNA - epididymis [nTPM]":"3.5","Tissue RNA - esophagus [nTPM]":"5.1","Tissue RNA - fallopian tube [nTPM]":"2.8","Tissue RNA - gallbladder [nTPM]":"3.7","Tissue RNA - heart muscle [nTPM]":"2.0","Tissue RNA - hippocampal formation [nTPM]":"1.6","Tissue RNA - hypothalamus [nTPM]":"1.8","Tissue RNA - kidney [nTPM]":"3.8","Tissue RNA - liver [nTPM]":"4.5","Tissue RNA - lung [nTPM]":"6.7","Tissue RNA - lymph node [nTPM]":"3.5","Tissue RNA - medulla oblongata [nTPM]":"2.8","Tissue RNA - midbrain [nTPM]":"2.7","Tissue RNA - ovary [nTPM]":"2.4","Tissue RNA - pancreas [nTPM]":"4.0","Tissue RNA - parathyroid gland [nTPM]":"3.3","Tissue RNA - pituitary gland [nTPM]":"0.6","Tissue RNA - placenta [nTPM]":"3.6","Tissue RNA - pons [nTPM]":"2.2","Tissue RNA - prostate [nTPM]":"2.7","Tissue RNA - rectum [nTPM]":"3.7","Tissue RNA - retina [nTPM]":"4.5","Tissue RNA - salivary gland [nTPM]":"4.6","Tissue RNA - seminal vesicle [nTPM]":"1.7","Tissue RNA - skeletal muscle [nTPM]":"1.3","Tissue RNA - skin 1 [nTPM]":"1.4","Tissue RNA - small intestine [nTPM]":"2.4","Tissue RNA - smooth muscle [nTPM]":"2.5","Tissue RNA - spinal cord [nTPM]":"2.2","Tissue RNA - spleen [nTPM]":"2.0","Tissue RNA - stomach 1 [nTPM]":"2.8","Tissue RNA - testis [nTPM]":"2.6","Tissue RNA - thalamus [nTPM]":"2.3","Tissue RNA - thymus [nTPM]":"4.0","Tissue RNA - thyroid gland [nTPM]":"4.4","Tissue RNA - tongue [nTPM]":"1.3","Tissue RNA - tonsil [nTPM]":"4.7","Tissue RNA - urinary bladder [nTPM]":"10.3","Tissue RNA - vagina [nTPM]":"1.9","Tissue RNA - white matter [nTPM]":"5.8","Cell RNA - A-431 [nTPM]":"14.5","Cell RNA - A549 [nTPM]":"8.3","Cell RNA - AF22 [nTPM]":"9.1","Cell RNA - AN3-CA [nTPM]":"5.0","Cell RNA - ASC diff [nTPM]":"2.6","Cell RNA - ASC TERT1 [nTPM]":"2.8","Cell RNA - BEWO [nTPM]":"7.0","Cell RNA - BJ [nTPM]":"3.7","Cell RNA - BJ hTERT+ [nTPM]":"5.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.3","Cell RNA - CACO-2 [nTPM]":"9.2","Cell RNA - CAPAN-2 [nTPM]":"6.5","Cell RNA - Daudi [nTPM]":"6.6","Cell RNA - EFO-21 [nTPM]":"2.9","Cell RNA - fHDF\/TERT166 [nTPM]":"2.9","Cell RNA - GAMG [nTPM]":"9.0","Cell RNA - HaCaT [nTPM]":"5.8","Cell RNA - HAP1 [nTPM]":"14.3","Cell RNA - HBEC3-KT [nTPM]":"11.4","Cell RNA - HBF TERT88 [nTPM]":"12.6","Cell RNA - HDLM-2 [nTPM]":"6.1","Cell RNA - HEK 293 [nTPM]":"9.5","Cell RNA - HEL [nTPM]":"5.5","Cell RNA - HeLa [nTPM]":"11.0","Cell RNA - Hep G2 [nTPM]":"5.8","Cell RNA - HHSteC [nTPM]":"4.5","Cell RNA - HL-60 [nTPM]":"8.8","Cell RNA - HMC-1 [nTPM]":"2.9","Cell RNA - HSkMC [nTPM]":"3.3","Cell RNA - hTCEpi [nTPM]":"8.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.0","Cell RNA - hTERT-HME1 [nTPM]":"16.0","Cell RNA - hTERT-RPE1 [nTPM]":"2.4","Cell RNA - HUVEC TERT2 [nTPM]":"5.0","Cell RNA - JURKAT [nTPM]":"5.2","Cell RNA - K-562 [nTPM]":"6.4","Cell RNA - Karpas-707 [nTPM]":"7.0","Cell RNA - LHCN-M2 [nTPM]":"5.1","Cell RNA - MCF7 [nTPM]":"9.2","Cell RNA - MOLT-4 [nTPM]":"9.0","Cell RNA - NB-4 [nTPM]":"3.4","Cell RNA - NTERA-2 [nTPM]":"4.7","Cell RNA - OE19 [nTPM]":"5.5","Cell RNA - PC-3 [nTPM]":"8.2","Cell RNA - REH [nTPM]":"3.0","Cell RNA - RH-30 [nTPM]":"12.4","Cell RNA - RPMI-8226 [nTPM]":"10.7","Cell RNA - RPTEC TERT1 [nTPM]":"5.6","Cell RNA - RT4 [nTPM]":"9.4","Cell RNA - SCLC-21H [nTPM]":"6.2","Cell RNA - SH-SY5Y [nTPM]":"9.4","Cell RNA - SiHa [nTPM]":"6.9","Cell RNA - SK-BR-3 [nTPM]":"6.8","Cell RNA - SK-MEL-30 [nTPM]":"14.4","Cell RNA - SuSa [nTPM]":"8.7","Cell RNA - T-47d [nTPM]":"6.6","Cell RNA - THP-1 [nTPM]":"7.4","Cell RNA - TIME [nTPM]":"4.2","Cell RNA - U-138 MG [nTPM]":"6.2","Cell RNA - U-2 OS [nTPM]":"2.4","Cell RNA - U-2197 [nTPM]":"14.0","Cell RNA - U-251 MG [nTPM]":"7.3","Cell RNA - U-266\/70 [nTPM]":"5.4","Cell RNA - U-266\/84 [nTPM]":"7.2","Cell RNA - U-698 [nTPM]":"9.9","Cell RNA - U-87 MG [nTPM]":"9.4","Cell RNA - U-937 [nTPM]":"5.6","Cell RNA - WM-115 [nTPM]":"7.9","Blood RNA - basophil [nTPM]":"22.9","Blood RNA - classical monocyte [nTPM]":"3.8","Blood RNA - eosinophil [nTPM]":"4.3","Blood RNA - gdT-cell [nTPM]":"2.6","Blood RNA - intermediate monocyte [nTPM]":"6.3","Blood RNA - MAIT T-cell [nTPM]":"3.7","Blood RNA - memory B-cell [nTPM]":"3.0","Blood RNA - memory CD4 T-cell [nTPM]":"4.1","Blood RNA - memory CD8 T-cell [nTPM]":"2.6","Blood RNA - myeloid DC [nTPM]":"3.9","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"3.8","Blood RNA - naive CD8 T-cell [nTPM]":"2.9","Blood RNA - neutrophil [nTPM]":"5.2","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"8.6","Blood RNA - plasmacytoid DC [nTPM]":"2.6","Blood RNA - T-reg [nTPM]":"4.1","Blood RNA - total PBMC [nTPM]":"2.7","Brain RNA - amygdala [nTPM]":"2.2","Brain RNA - basal ganglia [nTPM]":"2.7","Brain RNA - cerebellum [nTPM]":"2.0","Brain RNA - cerebral cortex [nTPM]":"3.6","Brain RNA - hippocampal formation [nTPM]":"1.6","Brain RNA - hypothalamus [nTPM]":"1.8","Brain RNA - medulla oblongata [nTPM]":"2.8","Brain RNA - midbrain [nTPM]":"2.7","Brain RNA - pons [nTPM]":"2.2","Brain RNA - spinal cord [nTPM]":"2.2","Brain RNA - thalamus [nTPM]":"2.3","Brain RNA - white matter [nTPM]":"5.8","Single Cell Type RNA - Adipocytes [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"83.5","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"7.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"29.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"41.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"3.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"20.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.3","Single Cell Type RNA - dendritic cells [nTPM]":"7.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"7.6","Single Cell Type RNA - Early spermatids [nTPM]":"5.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"30.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.8","Single Cell Type RNA - Endothelial cells [nTPM]":"7.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.7","Single Cell Type RNA - Erythroid cells [nTPM]":"9.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.2","Single Cell Type RNA - Fibroblasts [nTPM]":"12.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"45.6","Single Cell Type RNA - granulocytes [nTPM]":"33.6","Single Cell Type RNA - Granulosa cells [nTPM]":"3.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"4.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.8","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"8.4","Single Cell Type RNA - Langerhans cells [nTPM]":"43.4","Single Cell Type RNA - Late spermatids [nTPM]":"4.4","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"18.1","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"3.6","Single Cell Type RNA - Muller glia cells [nTPM]":"4.2","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.3","Single Cell Type RNA - Paneth cells [nTPM]":"5.1","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"5.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"32.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.3","Single Cell Type RNA - Spermatocytes [nTPM]":"2.7","Single Cell Type RNA - Spermatogonia [nTPM]":"3.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"35.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"55.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"28.0","Single Cell Type RNA - T-cells [nTPM]":"11.7","Single Cell Type RNA - Theca cells [nTPM]":"2.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.0","Single Cell Type RNA - Urothelial cells [nTPM]":"62.2"},{"Gene":"PIGK","Gene synonym":["GPI8","hGPI8"],"Ensembl":"ENSG00000142892","Gene description":"Phosphatidylinositol glycan anchor biosynthesis class K","Uniprot":["Q92643"],"Chromosome":"1","Position":"77088989-77219430","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["GPI-anchor biosynthesis"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056383","HPA057040"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA056383":"AB_2683109","HPA057040":"AB_2683319"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.68e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-3"},"Tissue RNA - adipose tissue [nTPM]":"9.8","Tissue RNA - adrenal gland [nTPM]":"12.4","Tissue RNA - amygdala [nTPM]":"5.2","Tissue RNA - appendix [nTPM]":"6.3","Tissue RNA - basal ganglia [nTPM]":"6.6","Tissue RNA - bone marrow [nTPM]":"8.8","Tissue RNA - breast [nTPM]":"12.4","Tissue RNA - cerebellum [nTPM]":"6.1","Tissue RNA - cerebral cortex [nTPM]":"9.4","Tissue RNA - cervix [nTPM]":"9.7","Tissue RNA - choroid plexus [nTPM]":"5.7","Tissue RNA - colon [nTPM]":"8.5","Tissue RNA - duodenum [nTPM]":"6.9","Tissue RNA - endometrium 1 [nTPM]":"9.5","Tissue RNA - epididymis [nTPM]":"9.7","Tissue RNA - esophagus [nTPM]":"6.5","Tissue RNA - fallopian tube [nTPM]":"9.3","Tissue RNA - gallbladder [nTPM]":"10.0","Tissue RNA - heart muscle [nTPM]":"14.1","Tissue RNA - hippocampal formation [nTPM]":"6.0","Tissue RNA - hypothalamus [nTPM]":"6.4","Tissue RNA - kidney [nTPM]":"17.7","Tissue RNA - liver [nTPM]":"13.2","Tissue RNA - lung [nTPM]":"9.2","Tissue RNA - lymph node [nTPM]":"8.8","Tissue RNA - medulla oblongata [nTPM]":"5.9","Tissue RNA - midbrain [nTPM]":"5.5","Tissue RNA - ovary [nTPM]":"9.6","Tissue RNA - pancreas [nTPM]":"9.6","Tissue RNA - parathyroid gland [nTPM]":"16.3","Tissue RNA - pituitary gland [nTPM]":"6.5","Tissue RNA - placenta [nTPM]":"6.4","Tissue RNA - pons [nTPM]":"6.2","Tissue RNA - prostate [nTPM]":"11.2","Tissue RNA - rectum [nTPM]":"9.3","Tissue RNA - retina [nTPM]":"9.8","Tissue RNA - salivary gland [nTPM]":"9.5","Tissue RNA - seminal vesicle [nTPM]":"8.8","Tissue RNA - skeletal muscle [nTPM]":"7.0","Tissue RNA - skin 1 [nTPM]":"4.8","Tissue RNA - small intestine [nTPM]":"7.3","Tissue RNA - smooth muscle [nTPM]":"10.7","Tissue RNA - spinal cord [nTPM]":"6.8","Tissue RNA - spleen [nTPM]":"9.8","Tissue RNA - stomach 1 [nTPM]":"8.9","Tissue RNA - testis [nTPM]":"6.0","Tissue RNA - thalamus [nTPM]":"5.5","Tissue RNA - thymus [nTPM]":"8.5","Tissue RNA - thyroid gland [nTPM]":"16.3","Tissue RNA - tongue [nTPM]":"9.8","Tissue RNA - tonsil [nTPM]":"7.5","Tissue RNA - urinary bladder [nTPM]":"9.3","Tissue RNA - vagina [nTPM]":"4.2","Tissue RNA - white matter [nTPM]":"9.8","Cell RNA - A-431 [nTPM]":"12.3","Cell RNA - A549 [nTPM]":"14.2","Cell RNA - AF22 [nTPM]":"11.5","Cell RNA - AN3-CA [nTPM]":"14.7","Cell RNA - ASC diff [nTPM]":"64.1","Cell RNA - ASC TERT1 [nTPM]":"48.1","Cell RNA - BEWO [nTPM]":"18.6","Cell RNA - BJ [nTPM]":"24.4","Cell RNA - BJ hTERT+ [nTPM]":"33.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"25.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"35.6","Cell RNA - CACO-2 [nTPM]":"11.8","Cell RNA - CAPAN-2 [nTPM]":"12.2","Cell RNA - Daudi [nTPM]":"10.7","Cell RNA - EFO-21 [nTPM]":"24.4","Cell RNA - fHDF\/TERT166 [nTPM]":"43.1","Cell RNA - GAMG [nTPM]":"29.7","Cell RNA - HaCaT [nTPM]":"10.8","Cell RNA - HAP1 [nTPM]":"14.8","Cell RNA - HBEC3-KT [nTPM]":"20.8","Cell RNA - HBF TERT88 [nTPM]":"45.2","Cell RNA - HDLM-2 [nTPM]":"22.1","Cell RNA - HEK 293 [nTPM]":"15.1","Cell RNA - HEL [nTPM]":"14.6","Cell RNA - HeLa [nTPM]":"13.8","Cell RNA - Hep G2 [nTPM]":"11.1","Cell RNA - HHSteC [nTPM]":"14.4","Cell RNA - HL-60 [nTPM]":"32.5","Cell RNA - HMC-1 [nTPM]":"12.4","Cell RNA - HSkMC [nTPM]":"29.2","Cell RNA - hTCEpi [nTPM]":"11.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.7","Cell RNA - hTERT-HME1 [nTPM]":"22.9","Cell RNA - hTERT-RPE1 [nTPM]":"29.9","Cell RNA - HUVEC TERT2 [nTPM]":"37.4","Cell RNA - JURKAT [nTPM]":"13.2","Cell RNA - K-562 [nTPM]":"18.0","Cell RNA - Karpas-707 [nTPM]":"35.6","Cell RNA - LHCN-M2 [nTPM]":"39.0","Cell RNA - MCF7 [nTPM]":"8.3","Cell RNA - MOLT-4 [nTPM]":"10.3","Cell RNA - NB-4 [nTPM]":"13.2","Cell RNA - NTERA-2 [nTPM]":"10.4","Cell RNA - OE19 [nTPM]":"13.7","Cell RNA - PC-3 [nTPM]":"23.4","Cell RNA - REH [nTPM]":"12.0","Cell RNA - RH-30 [nTPM]":"33.7","Cell RNA - RPMI-8226 [nTPM]":"13.3","Cell RNA - RPTEC TERT1 [nTPM]":"31.9","Cell RNA - RT4 [nTPM]":"8.9","Cell RNA - SCLC-21H [nTPM]":"9.7","Cell RNA - SH-SY5Y [nTPM]":"9.1","Cell RNA - SiHa [nTPM]":"23.2","Cell RNA - SK-BR-3 [nTPM]":"20.8","Cell RNA - SK-MEL-30 [nTPM]":"27.1","Cell RNA - SuSa [nTPM]":"18.9","Cell RNA - T-47d [nTPM]":"10.0","Cell RNA - THP-1 [nTPM]":"18.5","Cell RNA - TIME [nTPM]":"21.5","Cell RNA - U-138 MG [nTPM]":"40.1","Cell RNA - U-2 OS [nTPM]":"15.6","Cell RNA - U-2197 [nTPM]":"21.9","Cell RNA - U-251 MG [nTPM]":"25.0","Cell RNA - U-266\/70 [nTPM]":"16.1","Cell RNA - U-266\/84 [nTPM]":"23.7","Cell RNA - U-698 [nTPM]":"10.7","Cell RNA - U-87 MG [nTPM]":"29.8","Cell RNA - U-937 [nTPM]":"40.5","Cell RNA - WM-115 [nTPM]":"16.2","Blood RNA - basophil [nTPM]":"7.2","Blood RNA - classical monocyte [nTPM]":"3.0","Blood RNA - eosinophil [nTPM]":"5.8","Blood RNA - gdT-cell [nTPM]":"5.8","Blood RNA - intermediate monocyte [nTPM]":"3.4","Blood RNA - MAIT T-cell [nTPM]":"6.0","Blood RNA - memory B-cell [nTPM]":"3.7","Blood RNA - memory CD4 T-cell [nTPM]":"6.0","Blood RNA - memory CD8 T-cell [nTPM]":"5.0","Blood RNA - myeloid DC [nTPM]":"5.7","Blood RNA - naive B-cell [nTPM]":"3.2","Blood RNA - naive CD4 T-cell [nTPM]":"7.5","Blood RNA - naive CD8 T-cell [nTPM]":"6.8","Blood RNA - neutrophil [nTPM]":"1.5","Blood RNA - NK-cell [nTPM]":"7.4","Blood RNA - non-classical monocyte [nTPM]":"3.5","Blood RNA - plasmacytoid DC [nTPM]":"3.9","Blood RNA - T-reg [nTPM]":"9.8","Blood RNA - total PBMC [nTPM]":"4.7","Brain RNA - amygdala [nTPM]":"5.2","Brain RNA - basal ganglia [nTPM]":"6.6","Brain RNA - cerebellum [nTPM]":"6.1","Brain RNA - cerebral cortex [nTPM]":"9.4","Brain RNA - hippocampal formation [nTPM]":"6.0","Brain RNA - hypothalamus [nTPM]":"6.4","Brain RNA - medulla oblongata [nTPM]":"5.9","Brain RNA - midbrain [nTPM]":"5.5","Brain RNA - pons [nTPM]":"6.2","Brain RNA - spinal cord [nTPM]":"6.8","Brain RNA - thalamus [nTPM]":"5.5","Brain RNA - white matter [nTPM]":"9.8","Single Cell Type RNA - Adipocytes [nTPM]":"17.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.1","Single Cell Type RNA - Astrocytes [nTPM]":"16.3","Single Cell Type RNA - B-cells [nTPM]":"14.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"23.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"14.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"23.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"18.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.0","Single Cell Type RNA - dendritic cells [nTPM]":"14.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"20.8","Single Cell Type RNA - Early spermatids [nTPM]":"2.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.5","Single Cell Type RNA - Endothelial cells [nTPM]":"18.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.8","Single Cell Type RNA - Erythroid cells [nTPM]":"16.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"51.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"35.7","Single Cell Type RNA - Fibroblasts [nTPM]":"29.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.1","Single Cell Type RNA - granulocytes [nTPM]":"17.7","Single Cell Type RNA - Granulosa cells [nTPM]":"14.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.3","Single Cell Type RNA - Hepatocytes [nTPM]":"29.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.3","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"40.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.4","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"14.5","Single Cell Type RNA - Langerhans cells [nTPM]":"13.9","Single Cell Type RNA - Late spermatids [nTPM]":"3.7","Single Cell Type RNA - Leydig cells [nTPM]":"19.6","Single Cell Type RNA - Macrophages [nTPM]":"11.9","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"26.2","Single Cell Type RNA - monocytes [nTPM]":"9.2","Single Cell Type RNA - Muller glia cells [nTPM]":"17.6","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"40.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"78.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.9","Single Cell Type RNA - Paneth cells [nTPM]":"8.5","Single Cell Type RNA - Peritubular cells [nTPM]":"27.4","Single Cell Type RNA - Plasma cells [nTPM]":"41.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"25.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.4","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"24.1","Single Cell Type RNA - Spermatocytes [nTPM]":"75.8","Single Cell Type RNA - Spermatogonia [nTPM]":"30.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.2","Single Cell Type RNA - T-cells [nTPM]":"15.5","Single Cell Type RNA - Theca cells [nTPM]":"12.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.7","Single Cell Type RNA - Urothelial cells [nTPM]":"11.5"},{"Gene":"PIGL","Gene synonym":[],"Ensembl":"ENSG00000108474","Gene description":"Phosphatidylinositol glycan anchor biosynthesis class L","Uniprot":["Q9Y2B2"],"Chromosome":"17","Position":"16217191-16351797","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["GPI-anchor biosynthesis"],"Molecular function":["Hydrolase"],"Disease involvement":["Deafness","Disease variant","Ichthyosis","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"46.7","Inhibitory neurons":"45.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012739"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA012739":"AB_1855367"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.57e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.47e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-3"},"Tissue RNA - adipose tissue [nTPM]":"9.6","Tissue RNA - adrenal gland [nTPM]":"8.6","Tissue RNA - amygdala [nTPM]":"8.0","Tissue RNA - appendix [nTPM]":"6.3","Tissue RNA - basal ganglia [nTPM]":"8.4","Tissue RNA - bone marrow [nTPM]":"5.6","Tissue RNA - breast [nTPM]":"10.1","Tissue RNA - cerebellum [nTPM]":"9.7","Tissue RNA - cerebral cortex [nTPM]":"10.4","Tissue RNA - cervix [nTPM]":"8.6","Tissue RNA - choroid plexus [nTPM]":"8.5","Tissue RNA - colon [nTPM]":"8.8","Tissue RNA - duodenum [nTPM]":"10.6","Tissue RNA - endometrium 1 [nTPM]":"8.3","Tissue RNA - epididymis [nTPM]":"11.8","Tissue RNA - esophagus [nTPM]":"8.1","Tissue RNA - fallopian tube [nTPM]":"8.9","Tissue RNA - gallbladder [nTPM]":"6.1","Tissue RNA - heart muscle [nTPM]":"5.6","Tissue RNA - hippocampal formation [nTPM]":"7.8","Tissue RNA - hypothalamus [nTPM]":"8.5","Tissue RNA - kidney [nTPM]":"9.0","Tissue RNA - liver [nTPM]":"14.3","Tissue RNA - lung [nTPM]":"7.7","Tissue RNA - lymph node [nTPM]":"7.8","Tissue RNA - medulla oblongata [nTPM]":"7.8","Tissue RNA - midbrain [nTPM]":"7.8","Tissue RNA - ovary [nTPM]":"10.4","Tissue RNA - pancreas [nTPM]":"10.2","Tissue RNA - parathyroid gland [nTPM]":"6.1","Tissue RNA - pituitary gland [nTPM]":"10.4","Tissue RNA - placenta [nTPM]":"6.3","Tissue RNA - pons [nTPM]":"8.2","Tissue RNA - prostate [nTPM]":"9.8","Tissue RNA - rectum [nTPM]":"8.4","Tissue RNA - retina [nTPM]":"6.3","Tissue RNA - salivary gland [nTPM]":"8.2","Tissue RNA - seminal vesicle [nTPM]":"6.1","Tissue RNA - skeletal muscle [nTPM]":"5.3","Tissue RNA - skin 1 [nTPM]":"11.4","Tissue RNA - small intestine [nTPM]":"10.1","Tissue RNA - smooth muscle [nTPM]":"5.9","Tissue RNA - spinal cord [nTPM]":"7.6","Tissue RNA - spleen [nTPM]":"7.8","Tissue RNA - stomach 1 [nTPM]":"10.5","Tissue RNA - testis [nTPM]":"8.7","Tissue RNA - thalamus [nTPM]":"8.2","Tissue RNA - thymus [nTPM]":"6.4","Tissue RNA - thyroid gland [nTPM]":"10.1","Tissue RNA - tongue [nTPM]":"3.3","Tissue RNA - tonsil [nTPM]":"8.3","Tissue RNA - urinary bladder [nTPM]":"7.8","Tissue RNA - vagina [nTPM]":"8.1","Tissue RNA - white matter [nTPM]":"9.4","Cell RNA - A-431 [nTPM]":"12.5","Cell RNA - A549 [nTPM]":"16.3","Cell RNA - AF22 [nTPM]":"11.4","Cell RNA - AN3-CA [nTPM]":"9.3","Cell RNA - ASC diff [nTPM]":"16.0","Cell RNA - ASC TERT1 [nTPM]":"15.2","Cell RNA - BEWO [nTPM]":"4.6","Cell RNA - BJ [nTPM]":"6.3","Cell RNA - BJ hTERT+ [nTPM]":"8.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.5","Cell RNA - CACO-2 [nTPM]":"17.2","Cell RNA - CAPAN-2 [nTPM]":"15.4","Cell RNA - Daudi [nTPM]":"6.6","Cell RNA - EFO-21 [nTPM]":"13.7","Cell RNA - fHDF\/TERT166 [nTPM]":"6.7","Cell RNA - GAMG [nTPM]":"6.9","Cell RNA - HaCaT [nTPM]":"17.4","Cell RNA - HAP1 [nTPM]":"14.7","Cell RNA - HBEC3-KT [nTPM]":"8.2","Cell RNA - HBF TERT88 [nTPM]":"15.0","Cell RNA - HDLM-2 [nTPM]":"13.1","Cell RNA - HEK 293 [nTPM]":"38.3","Cell RNA - HEL [nTPM]":"12.3","Cell RNA - HeLa [nTPM]":"13.6","Cell RNA - Hep G2 [nTPM]":"21.9","Cell RNA - HHSteC [nTPM]":"17.3","Cell RNA - HL-60 [nTPM]":"5.0","Cell RNA - HMC-1 [nTPM]":"7.4","Cell RNA - HSkMC [nTPM]":"12.5","Cell RNA - hTCEpi [nTPM]":"20.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.1","Cell RNA - hTERT-HME1 [nTPM]":"22.0","Cell RNA - hTERT-RPE1 [nTPM]":"10.9","Cell RNA - HUVEC TERT2 [nTPM]":"13.0","Cell RNA - JURKAT [nTPM]":"20.1","Cell RNA - K-562 [nTPM]":"14.6","Cell RNA - Karpas-707 [nTPM]":"7.3","Cell RNA - LHCN-M2 [nTPM]":"8.6","Cell RNA - MCF7 [nTPM]":"11.1","Cell RNA - MOLT-4 [nTPM]":"9.3","Cell RNA - NB-4 [nTPM]":"11.6","Cell RNA - NTERA-2 [nTPM]":"4.5","Cell RNA - OE19 [nTPM]":"25.2","Cell RNA - PC-3 [nTPM]":"8.3","Cell RNA - REH [nTPM]":"9.0","Cell RNA - RH-30 [nTPM]":"9.7","Cell RNA - RPMI-8226 [nTPM]":"15.6","Cell RNA - RPTEC TERT1 [nTPM]":"12.3","Cell RNA - RT4 [nTPM]":"6.6","Cell RNA - SCLC-21H [nTPM]":"6.0","Cell RNA - SH-SY5Y [nTPM]":"8.5","Cell RNA - SiHa [nTPM]":"6.7","Cell RNA - SK-BR-3 [nTPM]":"4.9","Cell RNA - SK-MEL-30 [nTPM]":"14.6","Cell RNA - SuSa [nTPM]":"29.9","Cell RNA - T-47d [nTPM]":"5.4","Cell RNA - THP-1 [nTPM]":"4.5","Cell RNA - TIME [nTPM]":"7.6","Cell RNA - U-138 MG [nTPM]":"9.1","Cell RNA - U-2 OS [nTPM]":"6.0","Cell RNA - U-2197 [nTPM]":"6.6","Cell RNA - U-251 MG [nTPM]":"19.8","Cell RNA - U-266\/70 [nTPM]":"5.5","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"10.3","Cell RNA - U-87 MG [nTPM]":"12.2","Cell RNA - U-937 [nTPM]":"12.5","Cell RNA - WM-115 [nTPM]":"6.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.7","Blood RNA - eosinophil [nTPM]":"4.7","Blood RNA - gdT-cell [nTPM]":"4.6","Blood RNA - intermediate monocyte [nTPM]":"2.6","Blood RNA - MAIT T-cell [nTPM]":"4.1","Blood RNA - memory B-cell [nTPM]":"3.7","Blood RNA - memory CD4 T-cell [nTPM]":"6.3","Blood RNA - memory CD8 T-cell [nTPM]":"3.7","Blood RNA - myeloid DC [nTPM]":"2.0","Blood RNA - naive B-cell [nTPM]":"2.8","Blood RNA - naive CD4 T-cell [nTPM]":"6.4","Blood RNA - naive CD8 T-cell [nTPM]":"5.5","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"4.8","Blood RNA - non-classical monocyte [nTPM]":"1.8","Blood RNA - plasmacytoid DC [nTPM]":"5.3","Blood RNA - T-reg [nTPM]":"5.4","Blood RNA - total PBMC [nTPM]":"2.5","Brain RNA - amygdala [nTPM]":"8.0","Brain RNA - basal ganglia [nTPM]":"8.4","Brain RNA - cerebellum [nTPM]":"9.7","Brain RNA - cerebral cortex [nTPM]":"10.4","Brain RNA - hippocampal formation [nTPM]":"7.8","Brain RNA - hypothalamus [nTPM]":"8.5","Brain RNA - medulla oblongata [nTPM]":"7.8","Brain RNA - midbrain [nTPM]":"7.8","Brain RNA - pons [nTPM]":"8.2","Brain RNA - spinal cord [nTPM]":"7.6","Brain RNA - thalamus [nTPM]":"8.2","Brain RNA - white matter [nTPM]":"9.4","Single Cell Type RNA - Adipocytes [nTPM]":"8.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.0","Single Cell Type RNA - Astrocytes [nTPM]":"19.2","Single Cell Type RNA - B-cells [nTPM]":"10.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"11.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"13.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.6","Single Cell Type RNA - dendritic cells [nTPM]":"9.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.3","Single Cell Type RNA - Early spermatids [nTPM]":"3.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.4","Single Cell Type RNA - Endothelial cells [nTPM]":"6.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.8","Single Cell Type RNA - Erythroid cells [nTPM]":"11.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"46.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.0","Single Cell Type RNA - Fibroblasts [nTPM]":"8.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.9","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"14.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"10.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.2","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"45.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.2","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"3.5","Single Cell Type RNA - Langerhans cells [nTPM]":"4.3","Single Cell Type RNA - Late spermatids [nTPM]":"2.9","Single Cell Type RNA - Leydig cells [nTPM]":"7.8","Single Cell Type RNA - Macrophages [nTPM]":"5.9","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"26.2","Single Cell Type RNA - monocytes [nTPM]":"3.6","Single Cell Type RNA - Muller glia cells [nTPM]":"5.2","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"24.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"34.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.4","Single Cell Type RNA - Paneth cells [nTPM]":"9.7","Single Cell Type RNA - Peritubular cells [nTPM]":"11.3","Single Cell Type RNA - Plasma cells [nTPM]":"12.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.3","Single Cell Type RNA - Spermatocytes [nTPM]":"16.1","Single Cell Type RNA - Spermatogonia [nTPM]":"8.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.6","Single Cell Type RNA - T-cells [nTPM]":"11.8","Single Cell Type RNA - Theca cells [nTPM]":"9.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.6","Single Cell Type RNA - Urothelial cells [nTPM]":"10.4"},{"Gene":"PIK3C2A","Gene synonym":["PI3K-C2alpha"],"Ensembl":"ENSG00000011405","Gene description":"Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha","Uniprot":["O00443"],"Chromosome":"11","Position":"17077730-17207983","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Endocytosis","Exocytosis"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Cataract","Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"217.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037641","HPA037642"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 43: Cardiomyocytes - Nuclear processes","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"HPA037641":"AB_10671878","HPA037642":"AB_10697081"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.66e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Tissue RNA - adipose tissue [nTPM]":"22.5","Tissue RNA - adrenal gland [nTPM]":"13.7","Tissue RNA - amygdala [nTPM]":"16.3","Tissue RNA - appendix [nTPM]":"12.3","Tissue RNA - basal ganglia [nTPM]":"25.9","Tissue RNA - bone marrow [nTPM]":"9.4","Tissue RNA - breast [nTPM]":"15.9","Tissue RNA - cerebellum [nTPM]":"22.5","Tissue RNA - cerebral cortex [nTPM]":"14.6","Tissue RNA - cervix [nTPM]":"16.1","Tissue RNA - choroid plexus [nTPM]":"17.4","Tissue RNA - colon [nTPM]":"13.2","Tissue RNA - duodenum [nTPM]":"14.9","Tissue RNA - endometrium 1 [nTPM]":"18.0","Tissue RNA - epididymis [nTPM]":"15.7","Tissue RNA - esophagus [nTPM]":"15.4","Tissue RNA - fallopian tube [nTPM]":"14.5","Tissue RNA - gallbladder [nTPM]":"19.0","Tissue RNA - heart muscle [nTPM]":"12.4","Tissue RNA - hippocampal formation [nTPM]":"10.5","Tissue RNA - hypothalamus [nTPM]":"14.0","Tissue RNA - kidney [nTPM]":"23.5","Tissue RNA - liver [nTPM]":"15.5","Tissue RNA - lung [nTPM]":"16.6","Tissue RNA - lymph node [nTPM]":"11.3","Tissue RNA - medulla oblongata [nTPM]":"16.6","Tissue RNA - midbrain [nTPM]":"16.1","Tissue RNA - ovary [nTPM]":"14.1","Tissue RNA - pancreas [nTPM]":"12.3","Tissue RNA - parathyroid gland [nTPM]":"43.6","Tissue RNA - pituitary gland [nTPM]":"10.3","Tissue RNA - placenta [nTPM]":"23.1","Tissue RNA - pons [nTPM]":"17.0","Tissue RNA - prostate [nTPM]":"16.4","Tissue RNA - rectum [nTPM]":"13.0","Tissue RNA - retina [nTPM]":"22.4","Tissue RNA - salivary gland [nTPM]":"11.8","Tissue RNA - seminal vesicle [nTPM]":"14.8","Tissue RNA - skeletal muscle [nTPM]":"6.4","Tissue RNA - skin 1 [nTPM]":"12.3","Tissue RNA - small intestine [nTPM]":"11.8","Tissue RNA - smooth muscle [nTPM]":"18.3","Tissue RNA - spinal cord [nTPM]":"13.8","Tissue RNA - spleen [nTPM]":"13.0","Tissue RNA - stomach 1 [nTPM]":"18.0","Tissue RNA - testis [nTPM]":"19.3","Tissue RNA - thalamus [nTPM]":"19.6","Tissue RNA - thymus [nTPM]":"9.4","Tissue RNA - thyroid gland [nTPM]":"30.7","Tissue RNA - tongue [nTPM]":"12.1","Tissue RNA - tonsil [nTPM]":"10.9","Tissue RNA - urinary bladder [nTPM]":"14.9","Tissue RNA - vagina [nTPM]":"12.0","Tissue RNA - white matter [nTPM]":"15.8","Cell RNA - A-431 [nTPM]":"53.8","Cell RNA - A549 [nTPM]":"24.1","Cell RNA - AF22 [nTPM]":"39.6","Cell RNA - AN3-CA [nTPM]":"24.8","Cell RNA - ASC diff [nTPM]":"28.0","Cell RNA - ASC TERT1 [nTPM]":"28.3","Cell RNA - BEWO [nTPM]":"35.3","Cell RNA - BJ [nTPM]":"33.2","Cell RNA - BJ hTERT+ [nTPM]":"35.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"33.2","Cell RNA - CACO-2 [nTPM]":"58.9","Cell RNA - CAPAN-2 [nTPM]":"6.0","Cell RNA - Daudi [nTPM]":"15.6","Cell RNA - EFO-21 [nTPM]":"16.2","Cell RNA - fHDF\/TERT166 [nTPM]":"28.6","Cell RNA - GAMG [nTPM]":"39.1","Cell RNA - HaCaT [nTPM]":"34.8","Cell RNA - HAP1 [nTPM]":"31.9","Cell RNA - HBEC3-KT [nTPM]":"25.4","Cell RNA - HBF TERT88 [nTPM]":"42.1","Cell RNA - HDLM-2 [nTPM]":"13.5","Cell RNA - HEK 293 [nTPM]":"27.6","Cell RNA - HEL [nTPM]":"9.8","Cell RNA - HeLa [nTPM]":"28.4","Cell RNA - Hep G2 [nTPM]":"23.3","Cell RNA - HHSteC [nTPM]":"30.6","Cell RNA - HL-60 [nTPM]":"12.3","Cell RNA - HMC-1 [nTPM]":"14.9","Cell RNA - HSkMC [nTPM]":"22.2","Cell RNA - hTCEpi [nTPM]":"17.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"23.6","Cell RNA - hTERT-HME1 [nTPM]":"45.8","Cell RNA - hTERT-RPE1 [nTPM]":"22.2","Cell RNA - HUVEC TERT2 [nTPM]":"57.7","Cell RNA - JURKAT [nTPM]":"9.9","Cell RNA - K-562 [nTPM]":"23.4","Cell RNA - Karpas-707 [nTPM]":"14.7","Cell RNA - LHCN-M2 [nTPM]":"18.6","Cell RNA - MCF7 [nTPM]":"16.6","Cell RNA - MOLT-4 [nTPM]":"6.6","Cell RNA - NB-4 [nTPM]":"7.7","Cell RNA - NTERA-2 [nTPM]":"22.6","Cell RNA - OE19 [nTPM]":"30.1","Cell RNA - PC-3 [nTPM]":"18.5","Cell RNA - REH [nTPM]":"6.9","Cell RNA - RH-30 [nTPM]":"41.1","Cell RNA - RPMI-8226 [nTPM]":"11.0","Cell RNA - RPTEC TERT1 [nTPM]":"29.6","Cell RNA - RT4 [nTPM]":"47.0","Cell RNA - SCLC-21H [nTPM]":"23.2","Cell RNA - SH-SY5Y [nTPM]":"20.5","Cell RNA - SiHa [nTPM]":"50.6","Cell RNA - SK-BR-3 [nTPM]":"21.4","Cell RNA - SK-MEL-30 [nTPM]":"23.2","Cell RNA - SuSa [nTPM]":"33.0","Cell RNA - T-47d [nTPM]":"12.7","Cell RNA - THP-1 [nTPM]":"12.3","Cell RNA - TIME [nTPM]":"72.5","Cell RNA - U-138 MG [nTPM]":"19.1","Cell RNA - U-2 OS [nTPM]":"27.4","Cell RNA - U-2197 [nTPM]":"50.1","Cell RNA - U-251 MG [nTPM]":"20.4","Cell RNA - U-266\/70 [nTPM]":"5.9","Cell RNA - U-266\/84 [nTPM]":"14.1","Cell RNA - U-698 [nTPM]":"12.8","Cell RNA - U-87 MG [nTPM]":"22.8","Cell RNA - U-937 [nTPM]":"11.3","Cell RNA - WM-115 [nTPM]":"22.6","Blood RNA - basophil [nTPM]":"1.7","Blood RNA - classical monocyte [nTPM]":"1.5","Blood RNA - eosinophil [nTPM]":"1.1","Blood RNA - gdT-cell [nTPM]":"1.7","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"1.1","Blood RNA - memory B-cell [nTPM]":"1.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"1.3","Blood RNA - myeloid DC [nTPM]":"2.1","Blood RNA - naive B-cell [nTPM]":"1.5","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.0","Blood RNA - neutrophil [nTPM]":"2.3","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"3.2","Blood RNA - plasmacytoid DC [nTPM]":"1.4","Blood RNA - T-reg [nTPM]":"0.9","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"16.3","Brain RNA - basal ganglia [nTPM]":"25.9","Brain RNA - cerebellum [nTPM]":"22.5","Brain RNA - cerebral cortex [nTPM]":"14.6","Brain RNA - hippocampal formation [nTPM]":"10.5","Brain RNA - hypothalamus [nTPM]":"14.0","Brain RNA - medulla oblongata [nTPM]":"16.6","Brain RNA - midbrain [nTPM]":"16.1","Brain RNA - pons [nTPM]":"17.0","Brain RNA - spinal cord [nTPM]":"13.8","Brain RNA - thalamus [nTPM]":"19.6","Brain RNA - white matter [nTPM]":"15.8","Single Cell Type RNA - Adipocytes [nTPM]":"93.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"76.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"62.0","Single Cell Type RNA - Astrocytes [nTPM]":"217.4","Single Cell Type RNA - B-cells [nTPM]":"25.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"35.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"26.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"49.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"34.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"25.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"29.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"33.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"70.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"29.6","Single Cell Type RNA - dendritic cells [nTPM]":"29.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"22.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"19.8","Single Cell Type RNA - Early spermatids [nTPM]":"35.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"51.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"35.1","Single Cell Type RNA - Endothelial cells [nTPM]":"87.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"28.7","Single Cell Type RNA - Erythroid cells [nTPM]":"11.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"57.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.9","Single Cell Type RNA - Fibroblasts [nTPM]":"28.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"45.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"72.4","Single Cell Type RNA - granulocytes [nTPM]":"32.2","Single Cell Type RNA - Granulosa cells [nTPM]":"22.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"106.7","Single Cell Type RNA - Hepatocytes [nTPM]":"32.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.2","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"81.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.5","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"46.3","Single Cell Type RNA - Langerhans cells [nTPM]":"33.1","Single Cell Type RNA - Late spermatids [nTPM]":"18.6","Single Cell Type RNA - Leydig cells [nTPM]":"25.7","Single Cell Type RNA - Macrophages [nTPM]":"27.0","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"69.3","Single Cell Type RNA - monocytes [nTPM]":"19.6","Single Cell Type RNA - Muller glia cells [nTPM]":"73.0","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"62.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"79.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"26.1","Single Cell Type RNA - Paneth cells [nTPM]":"13.1","Single Cell Type RNA - Peritubular cells [nTPM]":"31.2","Single Cell Type RNA - Plasma cells [nTPM]":"29.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"42.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"26.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"40.4","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"33.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"35.1","Single Cell Type RNA - Spermatocytes [nTPM]":"52.6","Single Cell Type RNA - Spermatogonia [nTPM]":"26.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"34.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"143.5","Single Cell Type RNA - T-cells [nTPM]":"25.3","Single Cell Type RNA - Theca cells [nTPM]":"25.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.7","Single Cell Type RNA - Urothelial cells [nTPM]":"37.3"},{"Gene":"PIKFYVE","Gene synonym":["FAB1","KIAA0981","MGC40423","p235","PIP5K","PIP5K3","ZFYVE29"],"Ensembl":"ENSG00000115020","Gene description":"Phosphoinositide kinase, FYVE-type zinc finger containing","Uniprot":["Q9Y2I7"],"Chromosome":"2","Position":"208266255-208358746","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":["Corneal dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"82.0","Oligodendrocyte precursor cells":"80.9","Oligodendrocytes":"81.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042604"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042604":"AB_10796580"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.81e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.4","Tissue RNA - adrenal gland [nTPM]":"7.9","Tissue RNA - amygdala [nTPM]":"7.6","Tissue RNA - appendix [nTPM]":"12.0","Tissue RNA - basal ganglia [nTPM]":"7.6","Tissue RNA - bone marrow [nTPM]":"28.8","Tissue RNA - breast [nTPM]":"8.1","Tissue RNA - cerebellum [nTPM]":"14.3","Tissue RNA - cerebral cortex [nTPM]":"9.3","Tissue RNA - cervix [nTPM]":"9.1","Tissue RNA - choroid plexus [nTPM]":"10.5","Tissue RNA - colon [nTPM]":"6.1","Tissue RNA - duodenum [nTPM]":"6.0","Tissue RNA - endometrium 1 [nTPM]":"9.3","Tissue RNA - epididymis [nTPM]":"11.9","Tissue RNA - esophagus [nTPM]":"6.3","Tissue RNA - fallopian tube [nTPM]":"6.4","Tissue RNA - gallbladder [nTPM]":"7.2","Tissue RNA - heart muscle [nTPM]":"7.4","Tissue RNA - hippocampal formation [nTPM]":"7.7","Tissue RNA - hypothalamus [nTPM]":"7.3","Tissue RNA - kidney [nTPM]":"10.6","Tissue RNA - liver [nTPM]":"10.5","Tissue RNA - lung [nTPM]":"7.8","Tissue RNA - lymph node [nTPM]":"17.4","Tissue RNA - medulla oblongata [nTPM]":"8.0","Tissue RNA - midbrain [nTPM]":"7.4","Tissue RNA - ovary [nTPM]":"10.0","Tissue RNA - pancreas [nTPM]":"22.2","Tissue RNA - parathyroid gland [nTPM]":"11.1","Tissue RNA - pituitary gland [nTPM]":"6.0","Tissue RNA - placenta [nTPM]":"9.7","Tissue RNA - pons [nTPM]":"6.9","Tissue RNA - prostate [nTPM]":"11.5","Tissue RNA - rectum [nTPM]":"7.4","Tissue RNA - retina [nTPM]":"17.3","Tissue RNA - salivary gland [nTPM]":"6.5","Tissue RNA - seminal vesicle [nTPM]":"8.0","Tissue RNA - skeletal muscle [nTPM]":"6.5","Tissue RNA - skin 1 [nTPM]":"8.2","Tissue RNA - small intestine [nTPM]":"7.3","Tissue RNA - smooth muscle [nTPM]":"8.9","Tissue RNA - spinal cord [nTPM]":"7.4","Tissue RNA - spleen [nTPM]":"15.1","Tissue RNA - stomach 1 [nTPM]":"8.0","Tissue RNA - testis [nTPM]":"14.0","Tissue RNA - thalamus [nTPM]":"8.9","Tissue RNA - thymus [nTPM]":"19.3","Tissue RNA - thyroid gland [nTPM]":"12.2","Tissue RNA - tongue [nTPM]":"9.0","Tissue RNA - tonsil [nTPM]":"16.1","Tissue RNA - urinary bladder [nTPM]":"8.2","Tissue RNA - vagina [nTPM]":"5.8","Tissue RNA - white matter [nTPM]":"11.1","Cell RNA - A-431 [nTPM]":"8.0","Cell RNA - A549 [nTPM]":"7.9","Cell RNA - AF22 [nTPM]":"18.3","Cell RNA - AN3-CA [nTPM]":"14.3","Cell RNA - ASC diff [nTPM]":"18.1","Cell RNA - ASC TERT1 [nTPM]":"21.4","Cell RNA - BEWO [nTPM]":"8.5","Cell RNA - BJ [nTPM]":"9.6","Cell RNA - BJ hTERT+ [nTPM]":"19.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.0","Cell RNA - CACO-2 [nTPM]":"11.3","Cell RNA - CAPAN-2 [nTPM]":"6.6","Cell RNA - Daudi [nTPM]":"9.2","Cell RNA - EFO-21 [nTPM]":"9.8","Cell RNA - fHDF\/TERT166 [nTPM]":"16.6","Cell RNA - GAMG [nTPM]":"21.7","Cell RNA - HaCaT [nTPM]":"8.0","Cell RNA - HAP1 [nTPM]":"16.1","Cell RNA - HBEC3-KT [nTPM]":"10.8","Cell RNA - HBF TERT88 [nTPM]":"18.8","Cell RNA - HDLM-2 [nTPM]":"7.9","Cell RNA - HEK 293 [nTPM]":"10.1","Cell RNA - HEL [nTPM]":"33.0","Cell RNA - HeLa [nTPM]":"15.6","Cell RNA - Hep G2 [nTPM]":"10.2","Cell RNA - HHSteC [nTPM]":"13.7","Cell RNA - HL-60 [nTPM]":"29.5","Cell RNA - HMC-1 [nTPM]":"28.5","Cell RNA - HSkMC [nTPM]":"16.0","Cell RNA - hTCEpi [nTPM]":"11.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.0","Cell RNA - hTERT-HME1 [nTPM]":"24.1","Cell RNA - hTERT-RPE1 [nTPM]":"18.5","Cell RNA - HUVEC TERT2 [nTPM]":"18.3","Cell RNA - JURKAT [nTPM]":"24.1","Cell RNA - K-562 [nTPM]":"22.7","Cell RNA - Karpas-707 [nTPM]":"16.1","Cell RNA - LHCN-M2 [nTPM]":"14.0","Cell RNA - MCF7 [nTPM]":"3.4","Cell RNA - MOLT-4 [nTPM]":"26.9","Cell RNA - NB-4 [nTPM]":"22.1","Cell RNA - NTERA-2 [nTPM]":"15.2","Cell RNA - OE19 [nTPM]":"6.1","Cell RNA - PC-3 [nTPM]":"5.9","Cell RNA - REH [nTPM]":"9.9","Cell RNA - RH-30 [nTPM]":"14.2","Cell RNA - RPMI-8226 [nTPM]":"12.7","Cell RNA - RPTEC TERT1 [nTPM]":"14.2","Cell RNA - RT4 [nTPM]":"11.5","Cell RNA - SCLC-21H [nTPM]":"5.8","Cell RNA - SH-SY5Y [nTPM]":"13.8","Cell RNA - SiHa [nTPM]":"10.6","Cell RNA - SK-BR-3 [nTPM]":"6.8","Cell RNA - SK-MEL-30 [nTPM]":"19.2","Cell RNA - SuSa [nTPM]":"21.4","Cell RNA - T-47d [nTPM]":"4.3","Cell RNA - THP-1 [nTPM]":"31.3","Cell RNA - TIME [nTPM]":"21.2","Cell RNA - U-138 MG [nTPM]":"13.8","Cell RNA - U-2 OS [nTPM]":"9.2","Cell RNA - U-2197 [nTPM]":"9.4","Cell RNA - U-251 MG [nTPM]":"9.0","Cell RNA - U-266\/70 [nTPM]":"11.2","Cell RNA - U-266\/84 [nTPM]":"14.2","Cell RNA - U-698 [nTPM]":"19.2","Cell RNA - U-87 MG [nTPM]":"11.1","Cell RNA - U-937 [nTPM]":"25.2","Cell RNA - WM-115 [nTPM]":"13.9","Blood RNA - basophil [nTPM]":"0.9","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.9","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"4.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.2","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"3.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.9","Blood RNA - naive CD8 T-cell [nTPM]":"1.1","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"3.2","Blood RNA - non-classical monocyte [nTPM]":"0.7","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"0.9","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"7.6","Brain RNA - basal ganglia [nTPM]":"7.6","Brain RNA - cerebellum [nTPM]":"14.3","Brain RNA - cerebral cortex [nTPM]":"9.3","Brain RNA - hippocampal formation [nTPM]":"7.7","Brain RNA - hypothalamus [nTPM]":"7.3","Brain RNA - medulla oblongata [nTPM]":"8.0","Brain RNA - midbrain [nTPM]":"7.4","Brain RNA - pons [nTPM]":"6.9","Brain RNA - spinal cord [nTPM]":"7.4","Brain RNA - thalamus [nTPM]":"8.9","Brain RNA - white matter [nTPM]":"11.1","Single Cell Type RNA - Adipocytes [nTPM]":"18.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.2","Single Cell Type RNA - Astrocytes [nTPM]":"58.8","Single Cell Type RNA - B-cells [nTPM]":"82.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.6","Single Cell Type RNA - Bipolar cells [nTPM]":"21.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"10.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.1","Single Cell Type RNA - dendritic cells [nTPM]":"14.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.4","Single Cell Type RNA - Early spermatids [nTPM]":"10.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.4","Single Cell Type RNA - Endothelial cells [nTPM]":"18.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.6","Single Cell Type RNA - Erythroid cells [nTPM]":"25.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"72.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.7","Single Cell Type RNA - Fibroblasts [nTPM]":"15.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.7","Single Cell Type RNA - granulocytes [nTPM]":"36.1","Single Cell Type RNA - Granulosa cells [nTPM]":"18.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.2","Single Cell Type RNA - Hepatocytes [nTPM]":"19.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.4","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"67.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.6","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"29.9","Single Cell Type RNA - Langerhans cells [nTPM]":"32.5","Single Cell Type RNA - Late spermatids [nTPM]":"8.3","Single Cell Type RNA - Leydig cells [nTPM]":"18.6","Single Cell Type RNA - Macrophages [nTPM]":"28.5","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"48.7","Single Cell Type RNA - monocytes [nTPM]":"19.1","Single Cell Type RNA - Muller glia cells [nTPM]":"13.5","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"80.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"81.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.5","Single Cell Type RNA - Paneth cells [nTPM]":"5.9","Single Cell Type RNA - Peritubular cells [nTPM]":"13.5","Single Cell Type RNA - Plasma cells [nTPM]":"10.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.9","Single Cell Type RNA - Spermatocytes [nTPM]":"30.5","Single Cell Type RNA - Spermatogonia [nTPM]":"23.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.3","Single Cell Type RNA - T-cells [nTPM]":"21.5","Single Cell Type RNA - Theca cells [nTPM]":"13.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.8","Single Cell Type RNA - Urothelial cells [nTPM]":"11.4"},{"Gene":"PINK1","Gene synonym":["BRPK","PARK6"],"Ensembl":"ENSG00000158828","Gene description":"PTEN induced kinase 1","Uniprot":["Q9BXM7"],"Chromosome":"1","Position":"20633458-20651511","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Autophagy"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Neurodegeneration","Parkinson disease","Parkinsonism","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"384.4","tongue":"392.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"151.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"8.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001931","CAB026191"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB026191":null,"HPA001931":"AB_1079620"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.11e-16"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Tissue RNA - adipose tissue [nTPM]":"50.7","Tissue RNA - adrenal gland [nTPM]":"127.2","Tissue RNA - amygdala [nTPM]":"119.3","Tissue RNA - appendix [nTPM]":"13.7","Tissue RNA - basal ganglia [nTPM]":"103.4","Tissue RNA - bone marrow [nTPM]":"13.0","Tissue RNA - breast [nTPM]":"41.9","Tissue RNA - cerebellum [nTPM]":"104.6","Tissue RNA - cerebral cortex [nTPM]":"110.9","Tissue RNA - cervix [nTPM]":"37.9","Tissue RNA - choroid plexus [nTPM]":"73.0","Tissue RNA - colon [nTPM]":"62.3","Tissue RNA - duodenum [nTPM]":"32.3","Tissue RNA - endometrium 1 [nTPM]":"43.9","Tissue RNA - epididymis [nTPM]":"18.8","Tissue RNA - esophagus [nTPM]":"48.8","Tissue RNA - fallopian tube [nTPM]":"34.4","Tissue RNA - gallbladder [nTPM]":"23.5","Tissue RNA - heart muscle [nTPM]":"153.4","Tissue RNA - hippocampal formation [nTPM]":"106.6","Tissue RNA - hypothalamus [nTPM]":"107.0","Tissue RNA - kidney [nTPM]":"56.8","Tissue RNA - liver [nTPM]":"76.8","Tissue RNA - lung [nTPM]":"30.1","Tissue RNA - lymph node [nTPM]":"10.8","Tissue RNA - medulla oblongata [nTPM]":"118.5","Tissue RNA - midbrain [nTPM]":"127.8","Tissue RNA - ovary [nTPM]":"30.1","Tissue RNA - pancreas [nTPM]":"52.7","Tissue RNA - parathyroid gland [nTPM]":"66.5","Tissue RNA - pituitary gland [nTPM]":"33.4","Tissue RNA - placenta [nTPM]":"21.3","Tissue RNA - pons [nTPM]":"118.3","Tissue RNA - prostate [nTPM]":"37.1","Tissue RNA - rectum [nTPM]":"15.0","Tissue RNA - retina [nTPM]":"29.4","Tissue RNA - salivary gland [nTPM]":"55.0","Tissue RNA - seminal vesicle [nTPM]":"29.7","Tissue RNA - skeletal muscle [nTPM]":"384.4","Tissue RNA - skin 1 [nTPM]":"55.3","Tissue RNA - small intestine [nTPM]":"35.2","Tissue RNA - smooth muscle [nTPM]":"20.0","Tissue RNA - spinal cord [nTPM]":"124.9","Tissue RNA - spleen [nTPM]":"27.9","Tissue RNA - stomach 1 [nTPM]":"46.7","Tissue RNA - testis [nTPM]":"94.8","Tissue RNA - thalamus [nTPM]":"132.1","Tissue RNA - thymus [nTPM]":"12.3","Tissue RNA - thyroid gland [nTPM]":"41.6","Tissue RNA - tongue [nTPM]":"392.3","Tissue RNA - tonsil [nTPM]":"8.3","Tissue RNA - urinary bladder [nTPM]":"47.4","Tissue RNA - vagina [nTPM]":"42.7","Tissue RNA - white matter [nTPM]":"95.0","Cell RNA - A-431 [nTPM]":"49.9","Cell RNA - A549 [nTPM]":"22.2","Cell RNA - AF22 [nTPM]":"10.3","Cell RNA - AN3-CA [nTPM]":"29.6","Cell RNA - ASC diff [nTPM]":"34.6","Cell RNA - ASC TERT1 [nTPM]":"32.8","Cell RNA - BEWO [nTPM]":"10.7","Cell RNA - BJ [nTPM]":"68.2","Cell RNA - BJ hTERT+ [nTPM]":"67.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"32.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"56.1","Cell RNA - CACO-2 [nTPM]":"7.7","Cell RNA - CAPAN-2 [nTPM]":"39.3","Cell RNA - Daudi [nTPM]":"11.7","Cell RNA - EFO-21 [nTPM]":"52.6","Cell RNA - fHDF\/TERT166 [nTPM]":"69.9","Cell RNA - GAMG [nTPM]":"75.4","Cell RNA - HaCaT [nTPM]":"22.5","Cell RNA - HAP1 [nTPM]":"15.0","Cell RNA - HBEC3-KT [nTPM]":"36.2","Cell RNA - HBF TERT88 [nTPM]":"16.0","Cell RNA - HDLM-2 [nTPM]":"14.0","Cell RNA - HEK 293 [nTPM]":"56.8","Cell RNA - HEL [nTPM]":"5.9","Cell RNA - HeLa [nTPM]":"60.3","Cell RNA - Hep G2 [nTPM]":"12.1","Cell RNA - HHSteC [nTPM]":"26.8","Cell RNA - HL-60 [nTPM]":"6.3","Cell RNA - HMC-1 [nTPM]":"17.7","Cell RNA - HSkMC [nTPM]":"30.8","Cell RNA - hTCEpi [nTPM]":"38.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"40.6","Cell RNA - hTERT-HME1 [nTPM]":"13.9","Cell RNA - hTERT-RPE1 [nTPM]":"36.2","Cell RNA - HUVEC TERT2 [nTPM]":"21.3","Cell RNA - JURKAT [nTPM]":"10.7","Cell RNA - K-562 [nTPM]":"14.5","Cell RNA - Karpas-707 [nTPM]":"14.5","Cell RNA - LHCN-M2 [nTPM]":"23.6","Cell RNA - MCF7 [nTPM]":"21.2","Cell RNA - MOLT-4 [nTPM]":"9.2","Cell RNA - NB-4 [nTPM]":"14.1","Cell RNA - NTERA-2 [nTPM]":"4.6","Cell RNA - OE19 [nTPM]":"12.9","Cell RNA - PC-3 [nTPM]":"72.2","Cell RNA - REH [nTPM]":"7.9","Cell RNA - RH-30 [nTPM]":"18.0","Cell RNA - RPMI-8226 [nTPM]":"9.4","Cell RNA - RPTEC TERT1 [nTPM]":"20.1","Cell RNA - RT4 [nTPM]":"11.5","Cell RNA - SCLC-21H [nTPM]":"37.8","Cell RNA - SH-SY5Y [nTPM]":"14.8","Cell RNA - SiHa [nTPM]":"74.4","Cell RNA - SK-BR-3 [nTPM]":"24.2","Cell RNA - SK-MEL-30 [nTPM]":"20.8","Cell RNA - SuSa [nTPM]":"12.3","Cell RNA - T-47d [nTPM]":"8.0","Cell RNA - THP-1 [nTPM]":"21.6","Cell RNA - TIME [nTPM]":"32.6","Cell RNA - U-138 MG [nTPM]":"29.1","Cell RNA - U-2 OS [nTPM]":"14.9","Cell RNA - U-2197 [nTPM]":"49.2","Cell RNA - U-251 MG [nTPM]":"9.7","Cell RNA - U-266\/70 [nTPM]":"16.7","Cell RNA - U-266\/84 [nTPM]":"3.6","Cell RNA - U-698 [nTPM]":"5.4","Cell RNA - U-87 MG [nTPM]":"63.1","Cell RNA - U-937 [nTPM]":"17.9","Cell RNA - WM-115 [nTPM]":"14.0","Blood RNA - basophil [nTPM]":"3.6","Blood RNA - classical monocyte [nTPM]":"1.6","Blood RNA - eosinophil [nTPM]":"3.7","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.7","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"1.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.8","Blood RNA - neutrophil [nTPM]":"8.1","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"3.9","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"1.5","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"119.3","Brain RNA - basal ganglia [nTPM]":"103.4","Brain RNA - cerebellum [nTPM]":"104.6","Brain RNA - cerebral cortex [nTPM]":"110.9","Brain RNA - hippocampal formation [nTPM]":"106.6","Brain RNA - hypothalamus [nTPM]":"107.0","Brain RNA - medulla oblongata [nTPM]":"118.5","Brain RNA - midbrain [nTPM]":"127.8","Brain RNA - pons [nTPM]":"118.3","Brain RNA - spinal cord [nTPM]":"124.9","Brain RNA - thalamus [nTPM]":"132.1","Brain RNA - white matter [nTPM]":"95.0","Single Cell Type RNA - Adipocytes [nTPM]":"38.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.2","Single Cell Type RNA - Astrocytes [nTPM]":"16.3","Single Cell Type RNA - B-cells [nTPM]":"9.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"36.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"50.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"31.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"37.1","Single Cell Type RNA - Club cells [nTPM]":"9.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"26.3","Single Cell Type RNA - dendritic cells [nTPM]":"9.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"107.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"80.3","Single Cell Type RNA - Ductal cells [nTPM]":"24.0","Single Cell Type RNA - Early spermatids [nTPM]":"77.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.1","Single Cell Type RNA - Endothelial cells [nTPM]":"48.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.0","Single Cell Type RNA - Erythroid cells [nTPM]":"56.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"27.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"28.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"31.8","Single Cell Type RNA - Fibroblasts [nTPM]":"27.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"36.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"84.3","Single Cell Type RNA - Hepatocytes [nTPM]":"110.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.7","Single Cell Type RNA - Horizontal cells [nTPM]":"28.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"30.2","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"27.1","Single Cell Type RNA - Langerhans cells [nTPM]":"16.3","Single Cell Type RNA - Late spermatids [nTPM]":"151.4","Single Cell Type RNA - Leydig cells [nTPM]":"35.4","Single Cell Type RNA - Macrophages [nTPM]":"22.7","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"25.3","Single Cell Type RNA - monocytes [nTPM]":"10.1","Single Cell Type RNA - Muller glia cells [nTPM]":"69.7","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"56.6","Single Cell Type RNA - Paneth cells [nTPM]":"67.9","Single Cell Type RNA - Peritubular cells [nTPM]":"56.8","Single Cell Type RNA - Plasma cells [nTPM]":"27.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"67.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"66.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"109.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"69.0","Single Cell Type RNA - Sertoli cells [nTPM]":"85.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.2","Single Cell Type RNA - Spermatocytes [nTPM]":"120.8","Single Cell Type RNA - Spermatogonia [nTPM]":"24.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"34.2","Single Cell Type RNA - T-cells [nTPM]":"10.6","Single Cell Type RNA - Theca cells [nTPM]":"34.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.4","Single Cell Type RNA - Urothelial cells [nTPM]":"47.9"},{"Gene":"PIP5K1C","Gene synonym":["KIAA0589","LCCS3","PIP5Kgamma"],"Ensembl":"ENSG00000186111","Gene description":"Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma","Uniprot":["O60331"],"Chromosome":"19","Position":"3630183-3700468","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell adhesion","Chemotaxis","Endocytosis","Exocytosis","Phagocytosis"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"56.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-2197":"75.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017168"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA017168":"AB_1855395"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.79e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.28e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.32e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.00e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Tissue RNA - adipose tissue [nTPM]":"22.1","Tissue RNA - adrenal gland [nTPM]":"15.6","Tissue RNA - amygdala [nTPM]":"30.7","Tissue RNA - appendix [nTPM]":"11.5","Tissue RNA - basal ganglia [nTPM]":"36.6","Tissue RNA - bone marrow [nTPM]":"3.4","Tissue RNA - breast [nTPM]":"19.2","Tissue RNA - cerebellum [nTPM]":"19.4","Tissue RNA - cerebral cortex [nTPM]":"66.4","Tissue RNA - cervix [nTPM]":"24.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"62.2","Tissue RNA - duodenum [nTPM]":"8.6","Tissue RNA - endometrium 1 [nTPM]":"44.9","Tissue RNA - epididymis [nTPM]":"7.6","Tissue RNA - esophagus [nTPM]":"20.3","Tissue RNA - fallopian tube [nTPM]":"29.8","Tissue RNA - gallbladder [nTPM]":"8.2","Tissue RNA - heart muscle [nTPM]":"32.2","Tissue RNA - hippocampal formation [nTPM]":"40.2","Tissue RNA - hypothalamus [nTPM]":"5.0","Tissue RNA - kidney [nTPM]":"15.8","Tissue RNA - liver [nTPM]":"8.7","Tissue RNA - lung [nTPM]":"22.6","Tissue RNA - lymph node [nTPM]":"6.5","Tissue RNA - medulla oblongata [nTPM]":"13.3","Tissue RNA - midbrain [nTPM]":"7.7","Tissue RNA - ovary [nTPM]":"22.2","Tissue RNA - pancreas [nTPM]":"18.0","Tissue RNA - parathyroid gland [nTPM]":"10.7","Tissue RNA - pituitary gland [nTPM]":"20.6","Tissue RNA - placenta [nTPM]":"11.2","Tissue RNA - pons [nTPM]":"12.9","Tissue RNA - prostate [nTPM]":"33.9","Tissue RNA - rectum [nTPM]":"4.5","Tissue RNA - retina [nTPM]":"13.2","Tissue RNA - salivary gland [nTPM]":"18.1","Tissue RNA - seminal vesicle [nTPM]":"25.1","Tissue RNA - skeletal muscle [nTPM]":"17.7","Tissue RNA - skin 1 [nTPM]":"16.0","Tissue RNA - small intestine [nTPM]":"24.1","Tissue RNA - smooth muscle [nTPM]":"16.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"22.4","Tissue RNA - stomach 1 [nTPM]":"29.7","Tissue RNA - testis [nTPM]":"61.4","Tissue RNA - thalamus [nTPM]":"19.5","Tissue RNA - thymus [nTPM]":"5.3","Tissue RNA - thyroid gland [nTPM]":"21.1","Tissue RNA - tongue [nTPM]":"4.8","Tissue RNA - tonsil [nTPM]":"4.2","Tissue RNA - urinary bladder [nTPM]":"39.4","Tissue RNA - vagina [nTPM]":"24.7","Tissue RNA - white matter [nTPM]":"33.2","Cell RNA - A-431 [nTPM]":"18.9","Cell RNA - A549 [nTPM]":"18.0","Cell RNA - AF22 [nTPM]":"13.4","Cell RNA - AN3-CA [nTPM]":"18.0","Cell RNA - ASC diff [nTPM]":"25.5","Cell RNA - ASC TERT1 [nTPM]":"21.0","Cell RNA - BEWO [nTPM]":"20.3","Cell RNA - BJ [nTPM]":"36.1","Cell RNA - BJ hTERT+ [nTPM]":"22.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.3","Cell RNA - CACO-2 [nTPM]":"16.1","Cell RNA - CAPAN-2 [nTPM]":"5.2","Cell RNA - Daudi [nTPM]":"7.8","Cell RNA - EFO-21 [nTPM]":"13.6","Cell RNA - fHDF\/TERT166 [nTPM]":"39.0","Cell RNA - GAMG [nTPM]":"16.5","Cell RNA - HaCaT [nTPM]":"16.4","Cell RNA - HAP1 [nTPM]":"6.5","Cell RNA - HBEC3-KT [nTPM]":"11.7","Cell RNA - HBF TERT88 [nTPM]":"6.2","Cell RNA - HDLM-2 [nTPM]":"28.7","Cell RNA - HEK 293 [nTPM]":"11.9","Cell RNA - HEL [nTPM]":"9.0","Cell RNA - HeLa [nTPM]":"15.0","Cell RNA - Hep G2 [nTPM]":"13.1","Cell RNA - HHSteC [nTPM]":"22.0","Cell RNA - HL-60 [nTPM]":"9.4","Cell RNA - HMC-1 [nTPM]":"26.7","Cell RNA - HSkMC [nTPM]":"23.7","Cell RNA - hTCEpi [nTPM]":"9.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.4","Cell RNA - hTERT-HME1 [nTPM]":"4.1","Cell RNA - hTERT-RPE1 [nTPM]":"9.9","Cell RNA - HUVEC TERT2 [nTPM]":"25.6","Cell RNA - JURKAT [nTPM]":"11.5","Cell RNA - K-562 [nTPM]":"14.1","Cell RNA - Karpas-707 [nTPM]":"13.5","Cell RNA - LHCN-M2 [nTPM]":"14.4","Cell RNA - MCF7 [nTPM]":"15.7","Cell RNA - MOLT-4 [nTPM]":"11.2","Cell RNA - NB-4 [nTPM]":"6.6","Cell RNA - NTERA-2 [nTPM]":"14.4","Cell RNA - OE19 [nTPM]":"6.8","Cell RNA - PC-3 [nTPM]":"24.6","Cell RNA - REH [nTPM]":"21.4","Cell RNA - RH-30 [nTPM]":"7.2","Cell RNA - RPMI-8226 [nTPM]":"11.2","Cell RNA - RPTEC TERT1 [nTPM]":"11.5","Cell RNA - RT4 [nTPM]":"15.9","Cell RNA - SCLC-21H [nTPM]":"13.7","Cell RNA - SH-SY5Y [nTPM]":"12.0","Cell RNA - SiHa [nTPM]":"18.7","Cell RNA - SK-BR-3 [nTPM]":"10.1","Cell RNA - SK-MEL-30 [nTPM]":"11.1","Cell RNA - SuSa [nTPM]":"16.6","Cell RNA - T-47d [nTPM]":"7.9","Cell RNA - THP-1 [nTPM]":"14.1","Cell RNA - TIME [nTPM]":"57.3","Cell RNA - U-138 MG [nTPM]":"21.3","Cell RNA - U-2 OS [nTPM]":"11.8","Cell RNA - U-2197 [nTPM]":"75.1","Cell RNA - U-251 MG [nTPM]":"17.0","Cell RNA - U-266\/70 [nTPM]":"16.0","Cell RNA - U-266\/84 [nTPM]":"14.3","Cell RNA - U-698 [nTPM]":"3.5","Cell RNA - U-87 MG [nTPM]":"27.6","Cell RNA - U-937 [nTPM]":"19.2","Cell RNA - WM-115 [nTPM]":"15.0","Blood RNA - basophil [nTPM]":"1.0","Blood RNA - classical monocyte [nTPM]":"0.7","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.8","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.8","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"30.7","Brain RNA - basal ganglia [nTPM]":"36.6","Brain RNA - cerebellum [nTPM]":"19.4","Brain RNA - cerebral cortex [nTPM]":"66.4","Brain RNA - hippocampal formation [nTPM]":"40.2","Brain RNA - hypothalamus [nTPM]":"5.0","Brain RNA - medulla oblongata [nTPM]":"13.3","Brain RNA - midbrain [nTPM]":"7.7","Brain RNA - pons [nTPM]":"12.9","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"19.5","Brain RNA - white matter [nTPM]":"33.2","Single Cell Type RNA - Adipocytes [nTPM]":"20.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.0","Single Cell Type RNA - Astrocytes [nTPM]":"8.8","Single Cell Type RNA - B-cells [nTPM]":"6.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"56.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"3.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.8","Single Cell Type RNA - dendritic cells [nTPM]":"10.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.9","Single Cell Type RNA - Early spermatids [nTPM]":"11.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.0","Single Cell Type RNA - Endothelial cells [nTPM]":"22.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"30.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.4","Single Cell Type RNA - Fibroblasts [nTPM]":"10.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.6","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"10.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.1","Single Cell Type RNA - Hepatocytes [nTPM]":"4.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.7","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.7","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"19.6","Single Cell Type RNA - Langerhans cells [nTPM]":"13.2","Single Cell Type RNA - Late spermatids [nTPM]":"24.0","Single Cell Type RNA - Leydig cells [nTPM]":"14.9","Single Cell Type RNA - Macrophages [nTPM]":"15.5","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"22.5","Single Cell Type RNA - monocytes [nTPM]":"15.0","Single Cell Type RNA - Muller glia cells [nTPM]":"14.3","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.1","Single Cell Type RNA - Paneth cells [nTPM]":"13.2","Single Cell Type RNA - Peritubular cells [nTPM]":"24.0","Single Cell Type RNA - Plasma cells [nTPM]":"5.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"26.8","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.4","Single Cell Type RNA - Spermatocytes [nTPM]":"18.6","Single Cell Type RNA - Spermatogonia [nTPM]":"11.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.4","Single Cell Type RNA - T-cells [nTPM]":"8.0","Single Cell Type RNA - Theca cells [nTPM]":"11.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.2","Single Cell Type RNA - Urothelial cells [nTPM]":"5.3"},{"Gene":"PJVK","Gene synonym":["DFNB59"],"Ensembl":"ENSG00000204311","Gene description":"Pejvakin","Uniprot":["Q0ZLH3"],"Chromosome":"2","Position":"178451346-178462102","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"20.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"6.4","Alveolar cells type 2":"9.1","Distal tubular cells":"3.9","Granulosa cells":"6.1","Theca cells":"4.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"plasmacytoid DC":"2.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"2.8"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SuSa":"6.8"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042621"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA042621":"AB_10797503"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.21e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.92e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-3"},"Tissue RNA - adipose tissue [nTPM]":"3.0","Tissue RNA - adrenal gland [nTPM]":"1.8","Tissue RNA - amygdala [nTPM]":"6.9","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"7.2","Tissue RNA - bone marrow [nTPM]":"1.4","Tissue RNA - breast [nTPM]":"4.8","Tissue RNA - cerebellum [nTPM]":"6.9","Tissue RNA - cerebral cortex [nTPM]":"10.7","Tissue RNA - cervix [nTPM]":"2.7","Tissue RNA - choroid plexus [nTPM]":"6.9","Tissue RNA - colon [nTPM]":"1.9","Tissue RNA - duodenum [nTPM]":"1.2","Tissue RNA - endometrium 1 [nTPM]":"3.9","Tissue RNA - epididymis [nTPM]":"7.3","Tissue RNA - esophagus [nTPM]":"1.2","Tissue RNA - fallopian tube [nTPM]":"2.8","Tissue RNA - gallbladder [nTPM]":"2.9","Tissue RNA - heart muscle [nTPM]":"1.4","Tissue RNA - hippocampal formation [nTPM]":"7.0","Tissue RNA - hypothalamus [nTPM]":"7.0","Tissue RNA - kidney [nTPM]":"3.2","Tissue RNA - liver [nTPM]":"2.8","Tissue RNA - lung [nTPM]":"1.5","Tissue RNA - lymph node [nTPM]":"1.9","Tissue RNA - medulla oblongata [nTPM]":"7.6","Tissue RNA - midbrain [nTPM]":"7.3","Tissue RNA - ovary [nTPM]":"7.1","Tissue RNA - pancreas [nTPM]":"1.3","Tissue RNA - parathyroid gland [nTPM]":"1.1","Tissue RNA - pituitary gland [nTPM]":"4.1","Tissue RNA - placenta [nTPM]":"1.2","Tissue RNA - pons [nTPM]":"7.5","Tissue RNA - prostate [nTPM]":"2.8","Tissue RNA - rectum [nTPM]":"1.2","Tissue RNA - retina [nTPM]":"6.4","Tissue RNA - salivary gland [nTPM]":"2.7","Tissue RNA - seminal vesicle [nTPM]":"3.0","Tissue RNA - skeletal muscle [nTPM]":"3.5","Tissue RNA - skin 1 [nTPM]":"4.2","Tissue RNA - small intestine [nTPM]":"1.4","Tissue RNA - smooth muscle [nTPM]":"2.0","Tissue RNA - spinal cord [nTPM]":"7.3","Tissue RNA - spleen [nTPM]":"1.4","Tissue RNA - stomach 1 [nTPM]":"1.2","Tissue RNA - testis [nTPM]":"20.7","Tissue RNA - thalamus [nTPM]":"7.1","Tissue RNA - thymus [nTPM]":"1.2","Tissue RNA - thyroid gland [nTPM]":"2.5","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"1.7","Tissue RNA - urinary bladder [nTPM]":"1.9","Tissue RNA - vagina [nTPM]":"1.4","Tissue RNA - white matter [nTPM]":"7.7","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"1.8","Cell RNA - AF22 [nTPM]":"2.3","Cell RNA - AN3-CA [nTPM]":"1.9","Cell RNA - ASC diff [nTPM]":"3.0","Cell RNA - ASC TERT1 [nTPM]":"3.1","Cell RNA - BEWO [nTPM]":"1.2","Cell RNA - BJ [nTPM]":"1.5","Cell RNA - BJ hTERT+ [nTPM]":"1.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.0","Cell RNA - CACO-2 [nTPM]":"0.7","Cell RNA - CAPAN-2 [nTPM]":"3.1","Cell RNA - Daudi [nTPM]":"2.1","Cell RNA - EFO-21 [nTPM]":"1.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.9","Cell RNA - GAMG [nTPM]":"1.0","Cell RNA - HaCaT [nTPM]":"0.9","Cell RNA - HAP1 [nTPM]":"1.7","Cell RNA - HBEC3-KT [nTPM]":"1.0","Cell RNA - HBF TERT88 [nTPM]":"0.9","Cell RNA - HDLM-2 [nTPM]":"0.7","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"0.7","Cell RNA - HeLa [nTPM]":"2.9","Cell RNA - Hep G2 [nTPM]":"0.4","Cell RNA - HHSteC [nTPM]":"3.0","Cell RNA - HL-60 [nTPM]":"0.6","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"3.2","Cell RNA - hTCEpi [nTPM]":"2.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.4","Cell RNA - hTERT-HME1 [nTPM]":"3.2","Cell RNA - hTERT-RPE1 [nTPM]":"3.8","Cell RNA - HUVEC TERT2 [nTPM]":"1.5","Cell RNA - JURKAT [nTPM]":"4.1","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"1.3","Cell RNA - LHCN-M2 [nTPM]":"1.5","Cell RNA - MCF7 [nTPM]":"0.5","Cell RNA - MOLT-4 [nTPM]":"2.1","Cell RNA - NB-4 [nTPM]":"1.3","Cell RNA - NTERA-2 [nTPM]":"2.8","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.8","Cell RNA - REH [nTPM]":"2.7","Cell RNA - RH-30 [nTPM]":"1.7","Cell RNA - RPMI-8226 [nTPM]":"1.3","Cell RNA - RPTEC TERT1 [nTPM]":"2.0","Cell RNA - RT4 [nTPM]":"1.0","Cell RNA - SCLC-21H [nTPM]":"1.6","Cell RNA - SH-SY5Y [nTPM]":"1.3","Cell RNA - SiHa [nTPM]":"0.5","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.6","Cell RNA - SuSa [nTPM]":"6.8","Cell RNA - T-47d [nTPM]":"0.7","Cell RNA - THP-1 [nTPM]":"0.7","Cell RNA - TIME [nTPM]":"1.0","Cell RNA - U-138 MG [nTPM]":"1.5","Cell RNA - U-2 OS [nTPM]":"0.6","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"4.3","Cell RNA - U-266\/84 [nTPM]":"2.8","Cell RNA - U-698 [nTPM]":"0.7","Cell RNA - U-87 MG [nTPM]":"0.7","Cell RNA - U-937 [nTPM]":"1.1","Cell RNA - WM-115 [nTPM]":"0.6","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"2.8","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"6.9","Brain RNA - basal ganglia [nTPM]":"7.2","Brain RNA - cerebellum [nTPM]":"6.9","Brain RNA - cerebral cortex [nTPM]":"10.7","Brain RNA - hippocampal formation [nTPM]":"7.0","Brain RNA - hypothalamus [nTPM]":"7.0","Brain RNA - medulla oblongata [nTPM]":"7.6","Brain RNA - midbrain [nTPM]":"7.3","Brain RNA - pons [nTPM]":"7.5","Brain RNA - spinal cord [nTPM]":"7.3","Brain RNA - thalamus [nTPM]":"7.1","Brain RNA - white matter [nTPM]":"7.7","Single Cell Type RNA - Adipocytes [nTPM]":"1.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"1.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"6.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"4.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PKD1","Gene synonym":["PBP","Pc-1","TRPP1"],"Ensembl":"ENSG00000008710","Gene description":"Polycystin 1, transient receptor potential channel interacting","Uniprot":["P98161"],"Chromosome":"16","Position":"2088708-2135898","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Wnt signaling pathway"],"Molecular function":null,"Disease involvement":["Ciliopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pituitary gland":"72.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"138.1","Horizontal cells":"119.5","Inhibitory neurons":"101.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"65.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB046448"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"840000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 62: Horizontal cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB046448":"AB_2163360"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.43e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.35e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.38e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Tissue RNA - adipose tissue [nTPM]":"14.8","Tissue RNA - adrenal gland [nTPM]":"9.5","Tissue RNA - amygdala [nTPM]":"7.9","Tissue RNA - appendix [nTPM]":"4.9","Tissue RNA - basal ganglia [nTPM]":"10.4","Tissue RNA - bone marrow [nTPM]":"3.9","Tissue RNA - breast [nTPM]":"13.7","Tissue RNA - cerebellum [nTPM]":"65.4","Tissue RNA - cerebral cortex [nTPM]":"32.1","Tissue RNA - cervix [nTPM]":"22.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"40.3","Tissue RNA - duodenum [nTPM]":"3.8","Tissue RNA - endometrium 1 [nTPM]":"30.6","Tissue RNA - epididymis [nTPM]":"2.0","Tissue RNA - esophagus [nTPM]":"11.3","Tissue RNA - fallopian tube [nTPM]":"25.9","Tissue RNA - gallbladder [nTPM]":"3.7","Tissue RNA - heart muscle [nTPM]":"23.9","Tissue RNA - hippocampal formation [nTPM]":"9.6","Tissue RNA - hypothalamus [nTPM]":"1.6","Tissue RNA - kidney [nTPM]":"7.5","Tissue RNA - liver [nTPM]":"8.9","Tissue RNA - lung [nTPM]":"13.4","Tissue RNA - lymph node [nTPM]":"3.4","Tissue RNA - medulla oblongata [nTPM]":"16.2","Tissue RNA - midbrain [nTPM]":"1.7","Tissue RNA - ovary [nTPM]":"23.8","Tissue RNA - pancreas [nTPM]":"10.4","Tissue RNA - parathyroid gland [nTPM]":"2.3","Tissue RNA - pituitary gland [nTPM]":"72.4","Tissue RNA - placenta [nTPM]":"3.7","Tissue RNA - pons [nTPM]":"12.6","Tissue RNA - prostate [nTPM]":"19.9","Tissue RNA - rectum [nTPM]":"1.5","Tissue RNA - retina [nTPM]":"7.4","Tissue RNA - salivary gland [nTPM]":"10.4","Tissue RNA - seminal vesicle [nTPM]":"8.7","Tissue RNA - skeletal muscle [nTPM]":"47.7","Tissue RNA - skin 1 [nTPM]":"16.8","Tissue RNA - small intestine [nTPM]":"15.3","Tissue RNA - smooth muscle [nTPM]":"6.1","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"9.9","Tissue RNA - stomach 1 [nTPM]":"19.1","Tissue RNA - testis [nTPM]":"10.3","Tissue RNA - thalamus [nTPM]":"4.7","Tissue RNA - thymus [nTPM]":"2.8","Tissue RNA - thyroid gland [nTPM]":"10.3","Tissue RNA - tongue [nTPM]":"8.3","Tissue RNA - tonsil [nTPM]":"1.5","Tissue RNA - urinary bladder [nTPM]":"24.5","Tissue RNA - vagina [nTPM]":"15.5","Tissue RNA - white matter [nTPM]":"4.9","Cell RNA - A-431 [nTPM]":"4.2","Cell RNA - A549 [nTPM]":"8.9","Cell RNA - AF22 [nTPM]":"4.8","Cell RNA - AN3-CA [nTPM]":"10.9","Cell RNA - ASC diff [nTPM]":"8.2","Cell RNA - ASC TERT1 [nTPM]":"8.8","Cell RNA - BEWO [nTPM]":"9.3","Cell RNA - BJ [nTPM]":"14.2","Cell RNA - BJ hTERT+ [nTPM]":"5.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.0","Cell RNA - CACO-2 [nTPM]":"8.0","Cell RNA - CAPAN-2 [nTPM]":"3.1","Cell RNA - Daudi [nTPM]":"6.3","Cell RNA - EFO-21 [nTPM]":"8.9","Cell RNA - fHDF\/TERT166 [nTPM]":"7.3","Cell RNA - GAMG [nTPM]":"4.3","Cell RNA - HaCaT [nTPM]":"10.4","Cell RNA - HAP1 [nTPM]":"1.4","Cell RNA - HBEC3-KT [nTPM]":"2.1","Cell RNA - HBF TERT88 [nTPM]":"1.5","Cell RNA - HDLM-2 [nTPM]":"7.4","Cell RNA - HEK 293 [nTPM]":"7.1","Cell RNA - HEL [nTPM]":"3.9","Cell RNA - HeLa [nTPM]":"25.8","Cell RNA - Hep G2 [nTPM]":"3.2","Cell RNA - HHSteC [nTPM]":"16.1","Cell RNA - HL-60 [nTPM]":"5.4","Cell RNA - HMC-1 [nTPM]":"7.8","Cell RNA - HSkMC [nTPM]":"8.2","Cell RNA - hTCEpi [nTPM]":"7.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.5","Cell RNA - hTERT-HME1 [nTPM]":"4.6","Cell RNA - hTERT-RPE1 [nTPM]":"5.6","Cell RNA - HUVEC TERT2 [nTPM]":"3.1","Cell RNA - JURKAT [nTPM]":"6.6","Cell RNA - K-562 [nTPM]":"5.7","Cell RNA - Karpas-707 [nTPM]":"6.2","Cell RNA - LHCN-M2 [nTPM]":"2.6","Cell RNA - MCF7 [nTPM]":"6.9","Cell RNA - MOLT-4 [nTPM]":"7.7","Cell RNA - NB-4 [nTPM]":"16.5","Cell RNA - NTERA-2 [nTPM]":"4.3","Cell RNA - OE19 [nTPM]":"1.7","Cell RNA - PC-3 [nTPM]":"6.6","Cell RNA - REH [nTPM]":"21.6","Cell RNA - RH-30 [nTPM]":"7.7","Cell RNA - RPMI-8226 [nTPM]":"9.6","Cell RNA - RPTEC TERT1 [nTPM]":"2.1","Cell RNA - RT4 [nTPM]":"2.8","Cell RNA - SCLC-21H [nTPM]":"19.9","Cell RNA - SH-SY5Y [nTPM]":"22.2","Cell RNA - SiHa [nTPM]":"12.9","Cell RNA - SK-BR-3 [nTPM]":"8.5","Cell RNA - SK-MEL-30 [nTPM]":"8.9","Cell RNA - SuSa [nTPM]":"1.7","Cell RNA - T-47d [nTPM]":"7.0","Cell RNA - THP-1 [nTPM]":"18.3","Cell RNA - TIME [nTPM]":"7.4","Cell RNA - U-138 MG [nTPM]":"12.7","Cell RNA - U-2 OS [nTPM]":"10.3","Cell RNA - U-2197 [nTPM]":"9.6","Cell RNA - U-251 MG [nTPM]":"10.5","Cell RNA - U-266\/70 [nTPM]":"9.0","Cell RNA - U-266\/84 [nTPM]":"4.3","Cell RNA - U-698 [nTPM]":"7.0","Cell RNA - U-87 MG [nTPM]":"7.1","Cell RNA - U-937 [nTPM]":"5.0","Cell RNA - WM-115 [nTPM]":"8.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"7.9","Brain RNA - basal ganglia [nTPM]":"10.4","Brain RNA - cerebellum [nTPM]":"65.4","Brain RNA - cerebral cortex [nTPM]":"32.1","Brain RNA - hippocampal formation [nTPM]":"9.6","Brain RNA - hypothalamus [nTPM]":"1.6","Brain RNA - medulla oblongata [nTPM]":"16.2","Brain RNA - midbrain [nTPM]":"1.7","Brain RNA - pons [nTPM]":"12.6","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"4.7","Brain RNA - white matter [nTPM]":"4.9","Single Cell Type RNA - Adipocytes [nTPM]":"21.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.2","Single Cell Type RNA - Astrocytes [nTPM]":"61.7","Single Cell Type RNA - B-cells [nTPM]":"6.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"24.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"30.7","Single Cell Type RNA - Bipolar cells [nTPM]":"79.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"26.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"10.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.0","Single Cell Type RNA - dendritic cells [nTPM]":"11.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"5.2","Single Cell Type RNA - Early spermatids [nTPM]":"51.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"32.1","Single Cell Type RNA - Endothelial cells [nTPM]":"17.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"30.5","Single Cell Type RNA - Erythroid cells [nTPM]":"4.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"138.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.0","Single Cell Type RNA - Fibroblasts [nTPM]":"30.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.9","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"21.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.7","Single Cell Type RNA - Hepatocytes [nTPM]":"24.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.2","Single Cell Type RNA - Horizontal cells [nTPM]":"119.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"101.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.6","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"7.2","Single Cell Type RNA - Langerhans cells [nTPM]":"12.6","Single Cell Type RNA - Late spermatids [nTPM]":"10.6","Single Cell Type RNA - Leydig cells [nTPM]":"27.7","Single Cell Type RNA - Macrophages [nTPM]":"7.8","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"6.2","Single Cell Type RNA - Muller glia cells [nTPM]":"36.4","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"38.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"29.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.5","Single Cell Type RNA - Paneth cells [nTPM]":"5.9","Single Cell Type RNA - Peritubular cells [nTPM]":"45.9","Single Cell Type RNA - Plasma cells [nTPM]":"9.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"32.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"35.2","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"41.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"25.2","Single Cell Type RNA - Spermatocytes [nTPM]":"10.1","Single Cell Type RNA - Spermatogonia [nTPM]":"15.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.1","Single Cell Type RNA - T-cells [nTPM]":"10.9","Single Cell Type RNA - Theca cells [nTPM]":"10.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.2","Single Cell Type RNA - Urothelial cells [nTPM]":"6.9"},{"Gene":"PKD1L1","Gene synonym":["PRO19563"],"Ensembl":"ENSG00000158683","Gene description":"Polycystin 1 like 1, transient receptor potential channel interacting","Uniprot":["Q8TDX9"],"Chromosome":"7","Position":"47740202-47948466","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel"],"Disease involvement":["Heterotaxy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"9.1","Astrocytes":"13.4","Early spermatids":"11.8","Excitatory neurons":"25.7","Inhibitory neurons":"37.9","Microglial cells":"15.0","Oligodendrocyte precursor cells":"11.6","Oligodendrocytes":"17.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"1.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"T-47d":"5.9","U-266\/70":"14.7","U-266\/84":"5.7"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020422","HPA022424"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA020422":"AB_1855434","HPA022424":"AB_1855435"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.63e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.7","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"1.1","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"0.9","Tissue RNA - bone marrow [nTPM]":"1.1","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"2.1","Tissue RNA - cerebral cortex [nTPM]":"1.9","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"2.6","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"1.3","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.8","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.9","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.7","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.4","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"0.7","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"1.7","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"2.8","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"1.5","Tissue RNA - thalamus [nTPM]":"0.8","Tissue RNA - thymus [nTPM]":"1.5","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"3.3","Tissue RNA - tonsil [nTPM]":"0.6","Tissue RNA - urinary bladder [nTPM]":"0.6","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"1.1","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"0.7","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"0.8","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"1.2","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"0.8","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"0.8","Cell RNA - HAP1 [nTPM]":"0.5","Cell RNA - HBEC3-KT [nTPM]":"0.6","Cell RNA - HBF TERT88 [nTPM]":"0.6","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.8","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.3","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"1.1","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"1.1","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.7","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.4","Cell RNA - SiHa [nTPM]":"0.5","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"5.9","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.5","Cell RNA - U-2 OS [nTPM]":"1.1","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"14.7","Cell RNA - U-266\/84 [nTPM]":"5.7","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"0.9","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"1.1","Brain RNA - basal ganglia [nTPM]":"0.9","Brain RNA - cerebellum [nTPM]":"2.1","Brain RNA - cerebral cortex [nTPM]":"1.9","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"1.3","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.7","Brain RNA - pons [nTPM]":"0.7","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.8","Brain RNA - white matter [nTPM]":"1.1","Single Cell Type RNA - Adipocytes [nTPM]":"9.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"13.4","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"3.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"11.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"3.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"1.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.4","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"5.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"1.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.8","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PKD2","Gene synonym":["Pc-2","PC2","PKD4","TRPP2"],"Ensembl":"ENSG00000118762","Gene description":"Polycystin 2, transient receptor potential cation channel","Uniprot":["Q13563"],"Chromosome":"4","Position":"88007635-88077777","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Potassium transport","Transport","Wnt signaling pathway"],"Molecular function":["Calcium channel","Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Ciliopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"129.1","Inhibitory neurons":"148.6","Microglial cells":"95.5","Oligodendrocyte precursor cells":"178.9","Oligodendrocytes":"219.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ":"137.2","BJ hTERT+":"207.1","fHDF\/TERT166":"166.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004544","HPA015794","HPA055297"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB004544":"AB_672377","HPA015794":"AB_1855437","HPA055297":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Tissue RNA - adipose tissue [nTPM]":"30.7","Tissue RNA - adrenal gland [nTPM]":"24.2","Tissue RNA - amygdala [nTPM]":"9.6","Tissue RNA - appendix [nTPM]":"13.9","Tissue RNA - basal ganglia [nTPM]":"12.2","Tissue RNA - bone marrow [nTPM]":"10.7","Tissue RNA - breast [nTPM]":"18.6","Tissue RNA - cerebellum [nTPM]":"10.0","Tissue RNA - cerebral cortex [nTPM]":"12.0","Tissue RNA - cervix [nTPM]":"40.0","Tissue RNA - choroid plexus [nTPM]":"7.3","Tissue RNA - colon [nTPM]":"32.5","Tissue RNA - duodenum [nTPM]":"10.7","Tissue RNA - endometrium 1 [nTPM]":"61.1","Tissue RNA - epididymis [nTPM]":"14.7","Tissue RNA - esophagus [nTPM]":"12.7","Tissue RNA - fallopian tube [nTPM]":"39.3","Tissue RNA - gallbladder [nTPM]":"26.9","Tissue RNA - heart muscle [nTPM]":"19.7","Tissue RNA - hippocampal formation [nTPM]":"9.0","Tissue RNA - hypothalamus [nTPM]":"8.9","Tissue RNA - kidney [nTPM]":"48.6","Tissue RNA - liver [nTPM]":"15.0","Tissue RNA - lung [nTPM]":"22.2","Tissue RNA - lymph node [nTPM]":"11.5","Tissue RNA - medulla oblongata [nTPM]":"10.4","Tissue RNA - midbrain [nTPM]":"11.2","Tissue RNA - ovary [nTPM]":"47.7","Tissue RNA - pancreas [nTPM]":"14.8","Tissue RNA - parathyroid gland [nTPM]":"27.9","Tissue RNA - pituitary gland [nTPM]":"9.0","Tissue RNA - placenta [nTPM]":"24.5","Tissue RNA - pons [nTPM]":"10.0","Tissue RNA - prostate [nTPM]":"23.3","Tissue RNA - rectum [nTPM]":"13.2","Tissue RNA - retina [nTPM]":"14.0","Tissue RNA - salivary gland [nTPM]":"9.7","Tissue RNA - seminal vesicle [nTPM]":"39.2","Tissue RNA - skeletal muscle [nTPM]":"5.8","Tissue RNA - skin 1 [nTPM]":"10.3","Tissue RNA - small intestine [nTPM]":"14.8","Tissue RNA - smooth muscle [nTPM]":"53.7","Tissue RNA - spinal cord [nTPM]":"9.1","Tissue RNA - spleen [nTPM]":"10.9","Tissue RNA - stomach 1 [nTPM]":"20.0","Tissue RNA - testis [nTPM]":"10.3","Tissue RNA - thalamus [nTPM]":"11.9","Tissue RNA - thymus [nTPM]":"7.6","Tissue RNA - thyroid gland [nTPM]":"16.4","Tissue RNA - tongue [nTPM]":"11.7","Tissue RNA - tonsil [nTPM]":"8.7","Tissue RNA - urinary bladder [nTPM]":"20.6","Tissue RNA - vagina [nTPM]":"18.4","Tissue RNA - white matter [nTPM]":"14.6","Cell RNA - A-431 [nTPM]":"7.4","Cell RNA - A549 [nTPM]":"40.8","Cell RNA - AF22 [nTPM]":"44.9","Cell RNA - AN3-CA [nTPM]":"23.2","Cell RNA - ASC diff [nTPM]":"101.8","Cell RNA - ASC TERT1 [nTPM]":"67.6","Cell RNA - BEWO [nTPM]":"13.3","Cell RNA - BJ [nTPM]":"137.2","Cell RNA - BJ hTERT+ [nTPM]":"207.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"62.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"62.2","Cell RNA - CACO-2 [nTPM]":"2.0","Cell RNA - CAPAN-2 [nTPM]":"12.8","Cell RNA - Daudi [nTPM]":"4.0","Cell RNA - EFO-21 [nTPM]":"29.3","Cell RNA - fHDF\/TERT166 [nTPM]":"166.4","Cell RNA - GAMG [nTPM]":"24.0","Cell RNA - HaCaT [nTPM]":"9.1","Cell RNA - HAP1 [nTPM]":"8.1","Cell RNA - HBEC3-KT [nTPM]":"20.4","Cell RNA - HBF TERT88 [nTPM]":"54.5","Cell RNA - HDLM-2 [nTPM]":"21.2","Cell RNA - HEK 293 [nTPM]":"7.1","Cell RNA - HEL [nTPM]":"6.6","Cell RNA - HeLa [nTPM]":"21.8","Cell RNA - Hep G2 [nTPM]":"4.3","Cell RNA - HHSteC [nTPM]":"56.5","Cell RNA - HL-60 [nTPM]":"16.2","Cell RNA - HMC-1 [nTPM]":"12.9","Cell RNA - HSkMC [nTPM]":"56.4","Cell RNA - hTCEpi [nTPM]":"9.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"49.4","Cell RNA - hTERT-HME1 [nTPM]":"26.4","Cell RNA - hTERT-RPE1 [nTPM]":"85.6","Cell RNA - HUVEC TERT2 [nTPM]":"28.8","Cell RNA - JURKAT [nTPM]":"7.6","Cell RNA - K-562 [nTPM]":"0.9","Cell RNA - Karpas-707 [nTPM]":"10.9","Cell RNA - LHCN-M2 [nTPM]":"55.5","Cell RNA - MCF7 [nTPM]":"14.4","Cell RNA - MOLT-4 [nTPM]":"11.4","Cell RNA - NB-4 [nTPM]":"7.7","Cell RNA - NTERA-2 [nTPM]":"23.4","Cell RNA - OE19 [nTPM]":"5.3","Cell RNA - PC-3 [nTPM]":"6.7","Cell RNA - REH [nTPM]":"21.5","Cell RNA - RH-30 [nTPM]":"26.8","Cell RNA - RPMI-8226 [nTPM]":"6.0","Cell RNA - RPTEC TERT1 [nTPM]":"55.6","Cell RNA - RT4 [nTPM]":"17.2","Cell RNA - SCLC-21H [nTPM]":"9.0","Cell RNA - SH-SY5Y [nTPM]":"20.1","Cell RNA - SiHa [nTPM]":"25.5","Cell RNA - SK-BR-3 [nTPM]":"1.2","Cell RNA - SK-MEL-30 [nTPM]":"32.5","Cell RNA - SuSa [nTPM]":"45.0","Cell RNA - T-47d [nTPM]":"9.7","Cell RNA - THP-1 [nTPM]":"12.1","Cell RNA - TIME [nTPM]":"44.7","Cell RNA - U-138 MG [nTPM]":"59.1","Cell RNA - U-2 OS [nTPM]":"12.9","Cell RNA - U-2197 [nTPM]":"16.8","Cell RNA - U-251 MG [nTPM]":"18.8","Cell RNA - U-266\/70 [nTPM]":"8.7","Cell RNA - U-266\/84 [nTPM]":"2.9","Cell RNA - U-698 [nTPM]":"4.4","Cell RNA - U-87 MG [nTPM]":"35.2","Cell RNA - U-937 [nTPM]":"2.5","Cell RNA - WM-115 [nTPM]":"55.3","Blood RNA - basophil [nTPM]":"1.4","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"9.6","Brain RNA - basal ganglia [nTPM]":"12.2","Brain RNA - cerebellum [nTPM]":"10.0","Brain RNA - cerebral cortex [nTPM]":"12.0","Brain RNA - hippocampal formation [nTPM]":"9.0","Brain RNA - hypothalamus [nTPM]":"8.9","Brain RNA - medulla oblongata [nTPM]":"10.4","Brain RNA - midbrain [nTPM]":"11.2","Brain RNA - pons [nTPM]":"10.0","Brain RNA - spinal cord [nTPM]":"9.1","Brain RNA - thalamus [nTPM]":"11.9","Brain RNA - white matter [nTPM]":"14.6","Single Cell Type RNA - Adipocytes [nTPM]":"14.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.3","Single Cell Type RNA - Astrocytes [nTPM]":"59.4","Single Cell Type RNA - B-cells [nTPM]":"3.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.3","Single Cell Type RNA - Bipolar cells [nTPM]":"16.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"7.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"69.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.4","Single Cell Type RNA - dendritic cells [nTPM]":"2.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"14.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"41.7","Single Cell Type RNA - Endothelial cells [nTPM]":"19.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"13.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"129.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.4","Single Cell Type RNA - Fibroblasts [nTPM]":"42.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"12.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.4","Single Cell Type RNA - Hepatocytes [nTPM]":"10.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.2","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"148.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.4","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"5.0","Single Cell Type RNA - Langerhans cells [nTPM]":"6.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.1","Single Cell Type RNA - Leydig cells [nTPM]":"23.0","Single Cell Type RNA - Macrophages [nTPM]":"9.8","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"95.5","Single Cell Type RNA - monocytes [nTPM]":"9.5","Single Cell Type RNA - Muller glia cells [nTPM]":"17.3","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"178.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"219.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.2","Single Cell Type RNA - Paneth cells [nTPM]":"4.6","Single Cell Type RNA - Peritubular cells [nTPM]":"50.8","Single Cell Type RNA - Plasma cells [nTPM]":"3.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.9","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"53.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"31.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"3.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.7","Single Cell Type RNA - T-cells [nTPM]":"6.1","Single Cell Type RNA - Theca cells [nTPM]":"11.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.8","Single Cell Type RNA - Urothelial cells [nTPM]":"3.4"},{"Gene":"PKDCC","Gene synonym":["SgK493","Vlk"],"Ensembl":"ENSG00000162878","Gene description":"Protein kinase domain containing, cytoplasmic","Uniprot":["Q504Y2"],"Chromosome":"2","Position":"42048021-42058517","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted secreted proteins"],"Biological process":["Differentiation","Osteogenesis","Protein transport","Transport"],"Molecular function":["Developmental protein","Kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"85.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Enteroendocrine cells":"71.9","Fibroblasts":"55.4","Leydig cells":"137.6","Peritubular cells":"112.1","Rod photoreceptor cells":"95.9","Theca cells":"135.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AN3-CA":"85.9","ASC diff":"61.7","CACO-2":"101.0","HHSteC":"53.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026427","HPA026442","HPA026526"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"80000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026427":"AB_10600773","HPA026442":"AB_10601237","HPA026526":"AB_10602416"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-3"},"Tissue RNA - adipose tissue [nTPM]":"25.7","Tissue RNA - adrenal gland [nTPM]":"11.3","Tissue RNA - amygdala [nTPM]":"3.1","Tissue RNA - appendix [nTPM]":"4.9","Tissue RNA - basal ganglia [nTPM]":"3.8","Tissue RNA - bone marrow [nTPM]":"0.8","Tissue RNA - breast [nTPM]":"16.1","Tissue RNA - cerebellum [nTPM]":"0.8","Tissue RNA - cerebral cortex [nTPM]":"6.2","Tissue RNA - cervix [nTPM]":"31.8","Tissue RNA - choroid plexus [nTPM]":"6.4","Tissue RNA - colon [nTPM]":"20.3","Tissue RNA - duodenum [nTPM]":"10.7","Tissue RNA - endometrium 1 [nTPM]":"25.7","Tissue RNA - epididymis [nTPM]":"2.1","Tissue RNA - esophagus [nTPM]":"2.2","Tissue RNA - fallopian tube [nTPM]":"24.2","Tissue RNA - gallbladder [nTPM]":"3.3","Tissue RNA - heart muscle [nTPM]":"37.6","Tissue RNA - hippocampal formation [nTPM]":"4.8","Tissue RNA - hypothalamus [nTPM]":"1.0","Tissue RNA - kidney [nTPM]":"10.7","Tissue RNA - liver [nTPM]":"6.9","Tissue RNA - lung [nTPM]":"16.5","Tissue RNA - lymph node [nTPM]":"2.1","Tissue RNA - medulla oblongata [nTPM]":"1.5","Tissue RNA - midbrain [nTPM]":"1.6","Tissue RNA - ovary [nTPM]":"50.1","Tissue RNA - pancreas [nTPM]":"7.0","Tissue RNA - parathyroid gland [nTPM]":"1.1","Tissue RNA - pituitary gland [nTPM]":"6.8","Tissue RNA - placenta [nTPM]":"3.6","Tissue RNA - pons [nTPM]":"1.3","Tissue RNA - prostate [nTPM]":"12.2","Tissue RNA - rectum [nTPM]":"5.7","Tissue RNA - retina [nTPM]":"5.3","Tissue RNA - salivary gland [nTPM]":"20.7","Tissue RNA - seminal vesicle [nTPM]":"5.8","Tissue RNA - skeletal muscle [nTPM]":"85.5","Tissue RNA - skin 1 [nTPM]":"3.8","Tissue RNA - small intestine [nTPM]":"13.7","Tissue RNA - smooth muscle [nTPM]":"9.8","Tissue RNA - spinal cord [nTPM]":"1.4","Tissue RNA - spleen [nTPM]":"9.6","Tissue RNA - stomach 1 [nTPM]":"9.6","Tissue RNA - testis [nTPM]":"14.8","Tissue RNA - thalamus [nTPM]":"2.1","Tissue RNA - thymus [nTPM]":"6.4","Tissue RNA - thyroid gland [nTPM]":"5.1","Tissue RNA - tongue [nTPM]":"27.7","Tissue RNA - tonsil [nTPM]":"1.4","Tissue RNA - urinary bladder [nTPM]":"32.5","Tissue RNA - vagina [nTPM]":"17.4","Tissue RNA - white matter [nTPM]":"4.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"5.5","Cell RNA - AF22 [nTPM]":"14.0","Cell RNA - AN3-CA [nTPM]":"85.9","Cell RNA - ASC diff [nTPM]":"61.7","Cell RNA - ASC TERT1 [nTPM]":"0.7","Cell RNA - BEWO [nTPM]":"5.3","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.5","Cell RNA - CACO-2 [nTPM]":"101.0","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"1.7","Cell RNA - GAMG [nTPM]":"1.8","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"1.3","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"8.1","Cell RNA - HEK 293 [nTPM]":"3.5","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"3.3","Cell RNA - Hep G2 [nTPM]":"27.0","Cell RNA - HHSteC [nTPM]":"53.7","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.2","Cell RNA - HSkMC [nTPM]":"5.7","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.7","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"1.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.3","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"23.8","Cell RNA - OE19 [nTPM]":"6.8","Cell RNA - PC-3 [nTPM]":"1.7","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"27.3","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"2.8","Cell RNA - SH-SY5Y [nTPM]":"5.1","Cell RNA - SiHa [nTPM]":"1.3","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"16.3","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.7","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.6","Cell RNA - U-2 OS [nTPM]":"2.8","Cell RNA - U-2197 [nTPM]":"2.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.1","Brain RNA - basal ganglia [nTPM]":"3.8","Brain RNA - cerebellum [nTPM]":"0.8","Brain RNA - cerebral cortex [nTPM]":"6.2","Brain RNA - hippocampal formation [nTPM]":"4.8","Brain RNA - hypothalamus [nTPM]":"1.0","Brain RNA - medulla oblongata [nTPM]":"1.5","Brain RNA - midbrain [nTPM]":"1.6","Brain RNA - pons [nTPM]":"1.3","Brain RNA - spinal cord [nTPM]":"1.4","Brain RNA - thalamus [nTPM]":"2.1","Brain RNA - white matter [nTPM]":"4.7","Single Cell Type RNA - Adipocytes [nTPM]":"28.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"4.2","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"4.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"22.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"31.4","Single Cell Type RNA - Endothelial cells [nTPM]":"3.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"71.9","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.3","Single Cell Type RNA - Fibroblasts [nTPM]":"55.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"4.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.9","Single Cell Type RNA - Hepatocytes [nTPM]":"2.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"3.1","Single Cell Type RNA - Late spermatids [nTPM]":"5.4","Single Cell Type RNA - Leydig cells [nTPM]":"137.6","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"21.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.9","Single Cell Type RNA - Paneth cells [nTPM]":"16.0","Single Cell Type RNA - Peritubular cells [nTPM]":"112.1","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"95.9","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"1.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"135.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"35.9","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"PKLR","Gene synonym":[],"Ensembl":"ENSG00000143627","Gene description":"Pyruvate kinase L\/R","Uniprot":["P30613"],"Chromosome":"1","Position":"155289293-155301438","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Glycolysis"],"Molecular function":["Allosteric enzyme","Kinase","Transferase"],"Disease involvement":["Disease variant","Hereditary hemolytic anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"19.6","kidney":"25.1","liver":"92.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"9.3","Erythroid cells":"22.1","Hepatocytes":"16.3","Late spermatids":"23.0","Proximal enterocytes":"14.8","Proximal tubular cells":"48.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"liver cancer":"56.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"K-562":"107.8"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"1.6"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006653","CAB034376","CAB034378"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5200000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB034376":"AB_2163671","CAB034378":"AB_2252321","HPA006653":"AB_2667632"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"19.6","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"11.2","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.5","Tissue RNA - kidney [nTPM]":"25.1","Tissue RNA - liver [nTPM]":"92.5","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"1.2","Tissue RNA - small intestine [nTPM]":"7.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"2.7","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"11.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"107.8","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.5","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.5","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"9.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"22.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"16.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"23.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"48.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PLA2G4A","Gene synonym":["cPLA2-alpha","PLA2G4"],"Ensembl":"ENSG00000116711","Gene description":"Phospholipase A2 group IVA","Uniprot":["P47712"],"Chromosome":"1","Position":"186828949-186988981","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Glycerol metabolism","Leukotriene biosynthesis","Lipid biosynthesis","Lipid degradation","Lipid metabolism","Phospholipid degradation","Phospholipid metabolism","Prostaglandin biosynthesis","Prostaglandin metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"87.2","seminal vesicle":"48.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"33.4","Glandular and luminal cells":"28.1","Microglial cells":"115.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"classical monocyte":"6.8","eosinophil":"7.8","intermediate monocyte":"8.4","myeloid DC":"7.7","non-classical monocyte":"4.0","plasmacytoid DC":"3.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"dendritic cells":"7.7","granulocytes":"7.8","monocytes":"8.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"52.4","OE19":"84.4","RPMI-8226":"73.4","U-2197":"66.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010050","HPA050062","HPA054206"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"35000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB010050":"AB_631312","HPA050062":"AB_2681002","HPA054206":"AB_2682417"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.07e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.85e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.9","Tissue RNA - adrenal gland [nTPM]":"12.7","Tissue RNA - amygdala [nTPM]":"2.4","Tissue RNA - appendix [nTPM]":"6.3","Tissue RNA - basal ganglia [nTPM]":"3.4","Tissue RNA - bone marrow [nTPM]":"4.8","Tissue RNA - breast [nTPM]":"6.5","Tissue RNA - cerebellum [nTPM]":"2.8","Tissue RNA - cerebral cortex [nTPM]":"3.7","Tissue RNA - cervix [nTPM]":"14.5","Tissue RNA - choroid plexus [nTPM]":"3.2","Tissue RNA - colon [nTPM]":"11.9","Tissue RNA - duodenum [nTPM]":"11.1","Tissue RNA - endometrium 1 [nTPM]":"10.2","Tissue RNA - epididymis [nTPM]":"11.7","Tissue RNA - esophagus [nTPM]":"7.5","Tissue RNA - fallopian tube [nTPM]":"24.9","Tissue RNA - gallbladder [nTPM]":"6.2","Tissue RNA - heart muscle [nTPM]":"6.3","Tissue RNA - hippocampal formation [nTPM]":"2.4","Tissue RNA - hypothalamus [nTPM]":"3.3","Tissue RNA - kidney [nTPM]":"10.8","Tissue RNA - liver [nTPM]":"2.1","Tissue RNA - lung [nTPM]":"5.9","Tissue RNA - lymph node [nTPM]":"5.3","Tissue RNA - medulla oblongata [nTPM]":"4.4","Tissue RNA - midbrain [nTPM]":"3.5","Tissue RNA - ovary [nTPM]":"6.4","Tissue RNA - pancreas [nTPM]":"7.6","Tissue RNA - parathyroid gland [nTPM]":"87.2","Tissue RNA - pituitary gland [nTPM]":"2.0","Tissue RNA - placenta [nTPM]":"5.8","Tissue RNA - pons [nTPM]":"4.0","Tissue RNA - prostate [nTPM]":"8.8","Tissue RNA - rectum [nTPM]":"8.1","Tissue RNA - retina [nTPM]":"0.8","Tissue RNA - salivary gland [nTPM]":"6.3","Tissue RNA - seminal vesicle [nTPM]":"48.3","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"9.5","Tissue RNA - small intestine [nTPM]":"8.2","Tissue RNA - smooth muscle [nTPM]":"10.5","Tissue RNA - spinal cord [nTPM]":"4.1","Tissue RNA - spleen [nTPM]":"6.6","Tissue RNA - stomach 1 [nTPM]":"5.3","Tissue RNA - testis [nTPM]":"2.8","Tissue RNA - thalamus [nTPM]":"3.1","Tissue RNA - thymus [nTPM]":"1.5","Tissue RNA - thyroid gland [nTPM]":"2.6","Tissue RNA - tongue [nTPM]":"2.1","Tissue RNA - tonsil [nTPM]":"2.9","Tissue RNA - urinary bladder [nTPM]":"29.1","Tissue RNA - vagina [nTPM]":"8.4","Tissue RNA - white matter [nTPM]":"3.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"39.7","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"23.8","Cell RNA - ASC TERT1 [nTPM]":"9.5","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"1.5","Cell RNA - BJ hTERT+ [nTPM]":"15.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.2","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"15.5","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"6.8","Cell RNA - HaCaT [nTPM]":"2.8","Cell RNA - HAP1 [nTPM]":"24.6","Cell RNA - HBEC3-KT [nTPM]":"7.4","Cell RNA - HBF TERT88 [nTPM]":"0.8","Cell RNA - HDLM-2 [nTPM]":"12.5","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"7.6","Cell RNA - HeLa [nTPM]":"52.4","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"14.7","Cell RNA - HL-60 [nTPM]":"11.1","Cell RNA - HMC-1 [nTPM]":"3.8","Cell RNA - HSkMC [nTPM]":"5.4","Cell RNA - hTCEpi [nTPM]":"5.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.5","Cell RNA - hTERT-HME1 [nTPM]":"4.0","Cell RNA - hTERT-RPE1 [nTPM]":"2.4","Cell RNA - HUVEC TERT2 [nTPM]":"16.5","Cell RNA - JURKAT [nTPM]":"3.4","Cell RNA - K-562 [nTPM]":"16.7","Cell RNA - Karpas-707 [nTPM]":"5.9","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"2.1","Cell RNA - OE19 [nTPM]":"84.4","Cell RNA - PC-3 [nTPM]":"5.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"73.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"5.4","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"5.9","Cell RNA - SK-BR-3 [nTPM]":"2.0","Cell RNA - SK-MEL-30 [nTPM]":"7.3","Cell RNA - SuSa [nTPM]":"0.7","Cell RNA - T-47d [nTPM]":"0.8","Cell RNA - THP-1 [nTPM]":"15.0","Cell RNA - TIME [nTPM]":"3.3","Cell RNA - U-138 MG [nTPM]":"14.3","Cell RNA - U-2 OS [nTPM]":"1.9","Cell RNA - U-2197 [nTPM]":"66.3","Cell RNA - U-251 MG [nTPM]":"3.2","Cell RNA - U-266\/70 [nTPM]":"2.3","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"5.3","Cell RNA - U-937 [nTPM]":"32.4","Cell RNA - WM-115 [nTPM]":"20.7","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"6.8","Blood RNA - eosinophil [nTPM]":"7.8","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"8.4","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"7.7","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"4.0","Blood RNA - plasmacytoid DC [nTPM]":"3.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.7","Brain RNA - amygdala [nTPM]":"2.4","Brain RNA - basal ganglia [nTPM]":"3.4","Brain RNA - cerebellum [nTPM]":"2.8","Brain RNA - cerebral cortex [nTPM]":"3.7","Brain RNA - hippocampal formation [nTPM]":"2.4","Brain RNA - hypothalamus [nTPM]":"3.3","Brain RNA - medulla oblongata [nTPM]":"4.4","Brain RNA - midbrain [nTPM]":"3.5","Brain RNA - pons [nTPM]":"4.0","Brain RNA - spinal cord [nTPM]":"4.1","Brain RNA - thalamus [nTPM]":"3.1","Brain RNA - white matter [nTPM]":"3.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"21.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"4.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"3.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"33.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.7","Single Cell Type RNA - Endothelial cells [nTPM]":"6.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"3.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"11.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"28.1","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"3.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.6","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"7.9","Single Cell Type RNA - Langerhans cells [nTPM]":"8.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"10.5","Single Cell Type RNA - Macrophages [nTPM]":"11.5","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"115.2","Single Cell Type RNA - monocytes [nTPM]":"3.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.7","Single Cell Type RNA - Paneth cells [nTPM]":"7.3","Single Cell Type RNA - Peritubular cells [nTPM]":"14.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"1.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.8","Single Cell Type RNA - Urothelial cells [nTPM]":"13.4"},{"Gene":"PLA2G5","Gene synonym":[],"Ensembl":"ENSG00000127472","Gene description":"Phospholipase A2 group V","Uniprot":["P39877"],"Chromosome":"1","Position":"20028179-20091911","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":["Fatty acid metabolism","Lipid degradation","Lipid metabolism","Phagocytosis","Phospholipid degradation","Phospholipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"132.7","ovary":"47.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"75.3","Cone photoreceptor cells":"70.9","Leydig cells":"81.4","Peritubular cells":"73.4","Sertoli cells":"263.0","Smooth muscle cells":"63.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"13.0","prostate cancer":"3.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-2197":"1.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053361"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 43: Cardiomyocytes - Nuclear processes","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053361":"AB_2682127"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-3"},"Tissue RNA - adipose tissue [nTPM]":"8.9","Tissue RNA - adrenal gland [nTPM]":"1.5","Tissue RNA - amygdala [nTPM]":"8.7","Tissue RNA - appendix [nTPM]":"1.4","Tissue RNA - basal ganglia [nTPM]":"10.9","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"3.4","Tissue RNA - cerebellum [nTPM]":"10.5","Tissue RNA - cerebral cortex [nTPM]":"14.4","Tissue RNA - cervix [nTPM]":"1.2","Tissue RNA - choroid plexus [nTPM]":"22.1","Tissue RNA - colon [nTPM]":"33.7","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"1.8","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"4.4","Tissue RNA - fallopian tube [nTPM]":"6.4","Tissue RNA - gallbladder [nTPM]":"2.0","Tissue RNA - heart muscle [nTPM]":"132.7","Tissue RNA - hippocampal formation [nTPM]":"9.1","Tissue RNA - hypothalamus [nTPM]":"9.7","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"6.1","Tissue RNA - lung [nTPM]":"8.0","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"10.2","Tissue RNA - midbrain [nTPM]":"10.9","Tissue RNA - ovary [nTPM]":"47.6","Tissue RNA - pancreas [nTPM]":"0.9","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"4.7","Tissue RNA - pons [nTPM]":"9.2","Tissue RNA - prostate [nTPM]":"14.9","Tissue RNA - rectum [nTPM]":"2.3","Tissue RNA - retina [nTPM]":"18.9","Tissue RNA - salivary gland [nTPM]":"2.7","Tissue RNA - seminal vesicle [nTPM]":"7.7","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"1.7","Tissue RNA - small intestine [nTPM]":"3.0","Tissue RNA - smooth muscle [nTPM]":"3.3","Tissue RNA - spinal cord [nTPM]":"9.5","Tissue RNA - spleen [nTPM]":"1.6","Tissue RNA - stomach 1 [nTPM]":"6.3","Tissue RNA - testis [nTPM]":"10.1","Tissue RNA - thalamus [nTPM]":"11.8","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"2.4","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"1.2","Tissue RNA - urinary bladder [nTPM]":"17.6","Tissue RNA - vagina [nTPM]":"1.7","Tissue RNA - white matter [nTPM]":"8.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.5","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"1.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"8.7","Brain RNA - basal ganglia [nTPM]":"10.9","Brain RNA - cerebellum [nTPM]":"10.5","Brain RNA - cerebral cortex [nTPM]":"14.4","Brain RNA - hippocampal formation [nTPM]":"9.1","Brain RNA - hypothalamus [nTPM]":"9.7","Brain RNA - medulla oblongata [nTPM]":"10.2","Brain RNA - midbrain [nTPM]":"10.9","Brain RNA - pons [nTPM]":"9.2","Brain RNA - spinal cord [nTPM]":"9.5","Brain RNA - thalamus [nTPM]":"11.8","Brain RNA - white matter [nTPM]":"8.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"25.8","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"11.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"75.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"70.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"5.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"30.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"6.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.2","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"4.9","Single Cell Type RNA - Leydig cells [nTPM]":"81.4","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"30.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"73.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"32.1","Single Cell Type RNA - Sertoli cells [nTPM]":"263.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"63.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"PLA2G6","Gene synonym":["iPLA2","iPLA2beta","NBIA2","PARK14","PNPLA9"],"Ensembl":"ENSG00000184381","Gene description":"Phospholipase A2 group VI","Uniprot":["O60733"],"Chromosome":"22","Position":"38111495-38214778","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Chemotaxis","Lipid metabolism","Phospholipid metabolism"],"Molecular function":["Calmodulin-binding","Hydrolase"],"Disease involvement":["Disease variant","Dystonia","Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"28.5","Spermatocytes":"44.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"3.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"39.1","HMC-1":"25.6","U-266\/70":"20.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001171"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Centriolar satellite","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA001171":"AB_1079145"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.29e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.55e-4"},"Tissue RNA - adipose tissue [nTPM]":"20.0","Tissue RNA - adrenal gland [nTPM]":"22.2","Tissue RNA - amygdala [nTPM]":"14.1","Tissue RNA - appendix [nTPM]":"4.6","Tissue RNA - basal ganglia [nTPM]":"16.6","Tissue RNA - bone marrow [nTPM]":"12.2","Tissue RNA - breast [nTPM]":"19.5","Tissue RNA - cerebellum [nTPM]":"15.2","Tissue RNA - cerebral cortex [nTPM]":"20.3","Tissue RNA - cervix [nTPM]":"24.9","Tissue RNA - choroid plexus [nTPM]":"12.3","Tissue RNA - colon [nTPM]":"11.4","Tissue RNA - duodenum [nTPM]":"9.2","Tissue RNA - endometrium 1 [nTPM]":"17.8","Tissue RNA - epididymis [nTPM]":"10.6","Tissue RNA - esophagus [nTPM]":"10.3","Tissue RNA - fallopian tube [nTPM]":"26.2","Tissue RNA - gallbladder [nTPM]":"13.2","Tissue RNA - heart muscle [nTPM]":"9.5","Tissue RNA - hippocampal formation [nTPM]":"14.3","Tissue RNA - hypothalamus [nTPM]":"13.7","Tissue RNA - kidney [nTPM]":"24.0","Tissue RNA - liver [nTPM]":"13.3","Tissue RNA - lung [nTPM]":"10.4","Tissue RNA - lymph node [nTPM]":"8.5","Tissue RNA - medulla oblongata [nTPM]":"17.2","Tissue RNA - midbrain [nTPM]":"15.0","Tissue RNA - ovary [nTPM]":"24.3","Tissue RNA - pancreas [nTPM]":"16.1","Tissue RNA - parathyroid gland [nTPM]":"6.7","Tissue RNA - pituitary gland [nTPM]":"17.7","Tissue RNA - placenta [nTPM]":"4.1","Tissue RNA - pons [nTPM]":"19.5","Tissue RNA - prostate [nTPM]":"24.9","Tissue RNA - rectum [nTPM]":"2.8","Tissue RNA - retina [nTPM]":"8.3","Tissue RNA - salivary gland [nTPM]":"15.9","Tissue RNA - seminal vesicle [nTPM]":"9.2","Tissue RNA - skeletal muscle [nTPM]":"10.7","Tissue RNA - skin 1 [nTPM]":"17.2","Tissue RNA - small intestine [nTPM]":"12.5","Tissue RNA - smooth muscle [nTPM]":"3.4","Tissue RNA - spinal cord [nTPM]":"15.3","Tissue RNA - spleen [nTPM]":"17.1","Tissue RNA - stomach 1 [nTPM]":"13.2","Tissue RNA - testis [nTPM]":"42.1","Tissue RNA - thalamus [nTPM]":"15.4","Tissue RNA - thymus [nTPM]":"11.7","Tissue RNA - thyroid gland [nTPM]":"51.8","Tissue RNA - tongue [nTPM]":"4.4","Tissue RNA - tonsil [nTPM]":"4.6","Tissue RNA - urinary bladder [nTPM]":"13.2","Tissue RNA - vagina [nTPM]":"14.4","Tissue RNA - white matter [nTPM]":"25.5","Cell RNA - A-431 [nTPM]":"0.8","Cell RNA - A549 [nTPM]":"1.3","Cell RNA - AF22 [nTPM]":"2.6","Cell RNA - AN3-CA [nTPM]":"6.3","Cell RNA - ASC diff [nTPM]":"8.0","Cell RNA - ASC TERT1 [nTPM]":"5.5","Cell RNA - BEWO [nTPM]":"9.8","Cell RNA - BJ [nTPM]":"0.9","Cell RNA - BJ hTERT+ [nTPM]":"1.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.2","Cell RNA - CACO-2 [nTPM]":"3.2","Cell RNA - CAPAN-2 [nTPM]":"2.4","Cell RNA - Daudi [nTPM]":"5.9","Cell RNA - EFO-21 [nTPM]":"6.7","Cell RNA - fHDF\/TERT166 [nTPM]":"1.3","Cell RNA - GAMG [nTPM]":"0.9","Cell RNA - HaCaT [nTPM]":"3.5","Cell RNA - HAP1 [nTPM]":"2.2","Cell RNA - HBEC3-KT [nTPM]":"2.5","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"9.2","Cell RNA - HEK 293 [nTPM]":"11.1","Cell RNA - HEL [nTPM]":"39.1","Cell RNA - HeLa [nTPM]":"3.4","Cell RNA - Hep G2 [nTPM]":"3.5","Cell RNA - HHSteC [nTPM]":"3.1","Cell RNA - HL-60 [nTPM]":"2.6","Cell RNA - HMC-1 [nTPM]":"25.6","Cell RNA - HSkMC [nTPM]":"13.3","Cell RNA - hTCEpi [nTPM]":"3.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.3","Cell RNA - hTERT-HME1 [nTPM]":"4.6","Cell RNA - hTERT-RPE1 [nTPM]":"6.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.8","Cell RNA - JURKAT [nTPM]":"11.7","Cell RNA - K-562 [nTPM]":"8.0","Cell RNA - Karpas-707 [nTPM]":"13.3","Cell RNA - LHCN-M2 [nTPM]":"0.7","Cell RNA - MCF7 [nTPM]":"3.1","Cell RNA - MOLT-4 [nTPM]":"8.5","Cell RNA - NB-4 [nTPM]":"3.0","Cell RNA - NTERA-2 [nTPM]":"3.4","Cell RNA - OE19 [nTPM]":"2.7","Cell RNA - PC-3 [nTPM]":"1.3","Cell RNA - REH [nTPM]":"6.5","Cell RNA - RH-30 [nTPM]":"1.2","Cell RNA - RPMI-8226 [nTPM]":"6.1","Cell RNA - RPTEC TERT1 [nTPM]":"2.8","Cell RNA - RT4 [nTPM]":"5.9","Cell RNA - SCLC-21H [nTPM]":"7.1","Cell RNA - SH-SY5Y [nTPM]":"1.9","Cell RNA - SiHa [nTPM]":"1.9","Cell RNA - SK-BR-3 [nTPM]":"3.1","Cell RNA - SK-MEL-30 [nTPM]":"6.7","Cell RNA - SuSa [nTPM]":"3.9","Cell RNA - T-47d [nTPM]":"4.1","Cell RNA - THP-1 [nTPM]":"2.4","Cell RNA - TIME [nTPM]":"0.6","Cell RNA - U-138 MG [nTPM]":"2.1","Cell RNA - U-2 OS [nTPM]":"4.5","Cell RNA - U-2197 [nTPM]":"0.9","Cell RNA - U-251 MG [nTPM]":"0.6","Cell RNA - U-266\/70 [nTPM]":"20.6","Cell RNA - U-266\/84 [nTPM]":"2.7","Cell RNA - U-698 [nTPM]":"4.0","Cell RNA - U-87 MG [nTPM]":"4.0","Cell RNA - U-937 [nTPM]":"3.2","Cell RNA - WM-115 [nTPM]":"2.0","Blood RNA - basophil [nTPM]":"1.4","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.0","Blood RNA - memory CD8 T-cell [nTPM]":"1.5","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"1.2","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"3.7","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"1.6","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"14.1","Brain RNA - basal ganglia [nTPM]":"16.6","Brain RNA - cerebellum [nTPM]":"15.2","Brain RNA - cerebral cortex [nTPM]":"20.3","Brain RNA - hippocampal formation [nTPM]":"14.3","Brain RNA - hypothalamus [nTPM]":"13.7","Brain RNA - medulla oblongata [nTPM]":"17.2","Brain RNA - midbrain [nTPM]":"15.0","Brain RNA - pons [nTPM]":"19.5","Brain RNA - spinal cord [nTPM]":"15.3","Brain RNA - thalamus [nTPM]":"15.4","Brain RNA - white matter [nTPM]":"25.5","Single Cell Type RNA - Adipocytes [nTPM]":"5.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.7","Single Cell Type RNA - Astrocytes [nTPM]":"19.9","Single Cell Type RNA - B-cells [nTPM]":"4.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"9.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"5.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.3","Single Cell Type RNA - dendritic cells [nTPM]":"11.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.1","Single Cell Type RNA - Early spermatids [nTPM]":"28.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.4","Single Cell Type RNA - Endothelial cells [nTPM]":"3.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.4","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.7","Single Cell Type RNA - Fibroblasts [nTPM]":"3.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"10.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"3.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.7","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.6","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"18.3","Single Cell Type RNA - Leydig cells [nTPM]":"5.9","Single Cell Type RNA - Macrophages [nTPM]":"2.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"2.3","Single Cell Type RNA - Muller glia cells [nTPM]":"4.9","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"25.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.1","Single Cell Type RNA - Paneth cells [nTPM]":"12.6","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"4.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"21.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.4","Single Cell Type RNA - Spermatocytes [nTPM]":"44.5","Single Cell Type RNA - Spermatogonia [nTPM]":"7.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.9","Single Cell Type RNA - T-cells [nTPM]":"6.6","Single Cell Type RNA - Theca cells [nTPM]":"6.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.4","Single Cell Type RNA - Urothelial cells [nTPM]":"2.1"},{"Gene":"PLA2G7","Gene synonym":["LDL-PLA2","PAFAH"],"Ensembl":"ENSG00000146070","Gene description":"Phospholipase A2 group VII","Uniprot":["Q13093"],"Chromosome":"6","Position":"46704201-46735693","Protein class":["Candidate cardiovascular disease genes","Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted secreted proteins"],"Biological process":["Lipid degradation","Lipid metabolism","Phospholipid degradation","Phospholipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Asthma","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"27.2","placenta":"23.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Hofbauer cells":"372.2","Macrophages":"140.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"37.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"43.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"49","RNA blood lineage specific nTPM":{"dendritic cells":"14.1","monocytes":"43.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"NTERA-2":"1.7","PC-3":"3.4","RT4":"1.6","U-2 OS":"1.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":7380000,"Blood concentration - Conc. blood MS [pg\/L]":"290000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.5","Tissue RNA - adrenal gland [nTPM]":"3.1","Tissue RNA - amygdala [nTPM]":"1.6","Tissue RNA - appendix [nTPM]":"22.9","Tissue RNA - basal ganglia [nTPM]":"3.6","Tissue RNA - bone marrow [nTPM]":"2.8","Tissue RNA - breast [nTPM]":"2.6","Tissue RNA - cerebellum [nTPM]":"2.7","Tissue RNA - cerebral cortex [nTPM]":"4.5","Tissue RNA - cervix [nTPM]":"2.5","Tissue RNA - choroid plexus [nTPM]":"0.4","Tissue RNA - colon [nTPM]":"7.5","Tissue RNA - duodenum [nTPM]":"4.1","Tissue RNA - endometrium 1 [nTPM]":"4.8","Tissue RNA - epididymis [nTPM]":"1.1","Tissue RNA - esophagus [nTPM]":"0.6","Tissue RNA - fallopian tube [nTPM]":"1.9","Tissue RNA - gallbladder [nTPM]":"6.0","Tissue RNA - heart muscle [nTPM]":"0.6","Tissue RNA - hippocampal formation [nTPM]":"2.6","Tissue RNA - hypothalamus [nTPM]":"1.4","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"6.9","Tissue RNA - lung [nTPM]":"7.2","Tissue RNA - lymph node [nTPM]":"26.8","Tissue RNA - medulla oblongata [nTPM]":"3.9","Tissue RNA - midbrain [nTPM]":"2.6","Tissue RNA - ovary [nTPM]":"1.1","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"21.0","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"23.3","Tissue RNA - pons [nTPM]":"4.2","Tissue RNA - prostate [nTPM]":"13.1","Tissue RNA - rectum [nTPM]":"10.3","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"1.4","Tissue RNA - seminal vesicle [nTPM]":"2.6","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"3.6","Tissue RNA - small intestine [nTPM]":"3.3","Tissue RNA - smooth muscle [nTPM]":"2.8","Tissue RNA - spinal cord [nTPM]":"2.6","Tissue RNA - spleen [nTPM]":"27.2","Tissue RNA - stomach 1 [nTPM]":"2.9","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"8.9","Tissue RNA - thymus [nTPM]":"4.9","Tissue RNA - thyroid gland [nTPM]":"20.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"10.0","Tissue RNA - urinary bladder [nTPM]":"11.1","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"7.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.9","Cell RNA - HaCaT [nTPM]":"0.7","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.8","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"1.7","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"3.4","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"1.6","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.4","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.6","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.6","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"43.4","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"9.2","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"14.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"11.9","Brain RNA - amygdala [nTPM]":"1.6","Brain RNA - basal ganglia [nTPM]":"3.6","Brain RNA - cerebellum [nTPM]":"2.7","Brain RNA - cerebral cortex [nTPM]":"4.5","Brain RNA - hippocampal formation [nTPM]":"2.6","Brain RNA - hypothalamus [nTPM]":"1.4","Brain RNA - medulla oblongata [nTPM]":"3.9","Brain RNA - midbrain [nTPM]":"2.6","Brain RNA - pons [nTPM]":"4.2","Brain RNA - spinal cord [nTPM]":"2.6","Brain RNA - thalamus [nTPM]":"8.9","Brain RNA - white matter [nTPM]":"7.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"3.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"50.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.5","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"372.2","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"24.6","Single Cell Type RNA - Langerhans cells [nTPM]":"4.9","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"140.9","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"29.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.1","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"8.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"3.8"},{"Gene":"PLAU","Gene synonym":["UPA","URK"],"Ensembl":"ENSG00000122861","Gene description":"Plasminogen activator, urokinase","Uniprot":["P00749"],"Chromosome":"10","Position":"73909177-73917496","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Blood coagulation","Fibrinolysis","Hemostasis","Plasminogen activation"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"103.8","urinary bladder":"128.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Basal prostatic cells":"635.9","Basal respiratory cells":"237.3","Pancreatic endocrine cells":"613.9","Prostatic glandular cells":"695.0","Urothelial cells":"869.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"myeloid DC":"1.1","neutrophil":"2.1","plasmacytoid DC":"2.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"dendritic cells":"2.0","granulocytes":"2.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"856.0","LHCN-M2":"822.4","RPTEC TERT1":"3100.7","U-251 MG":"869.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070796"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":647000,"Blood concentration - Conc. blood MS [pg\/L]":"88000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA070796":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.38e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.70e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.04e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.32e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.51e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Tissue RNA - adipose tissue [nTPM]":"57.6","Tissue RNA - adrenal gland [nTPM]":"4.8","Tissue RNA - amygdala [nTPM]":"2.5","Tissue RNA - appendix [nTPM]":"41.7","Tissue RNA - basal ganglia [nTPM]":"2.7","Tissue RNA - bone marrow [nTPM]":"36.2","Tissue RNA - breast [nTPM]":"17.6","Tissue RNA - cerebellum [nTPM]":"2.7","Tissue RNA - cerebral cortex [nTPM]":"8.9","Tissue RNA - cervix [nTPM]":"9.3","Tissue RNA - choroid plexus [nTPM]":"4.4","Tissue RNA - colon [nTPM]":"13.1","Tissue RNA - duodenum [nTPM]":"11.9","Tissue RNA - endometrium 1 [nTPM]":"22.0","Tissue RNA - epididymis [nTPM]":"16.7","Tissue RNA - esophagus [nTPM]":"14.4","Tissue RNA - fallopian tube [nTPM]":"10.3","Tissue RNA - gallbladder [nTPM]":"28.5","Tissue RNA - heart muscle [nTPM]":"23.1","Tissue RNA - hippocampal formation [nTPM]":"2.4","Tissue RNA - hypothalamus [nTPM]":"2.9","Tissue RNA - kidney [nTPM]":"103.8","Tissue RNA - liver [nTPM]":"5.0","Tissue RNA - lung [nTPM]":"22.0","Tissue RNA - lymph node [nTPM]":"14.3","Tissue RNA - medulla oblongata [nTPM]":"3.8","Tissue RNA - midbrain [nTPM]":"2.9","Tissue RNA - ovary [nTPM]":"2.3","Tissue RNA - pancreas [nTPM]":"10.1","Tissue RNA - parathyroid gland [nTPM]":"8.3","Tissue RNA - pituitary gland [nTPM]":"2.9","Tissue RNA - placenta [nTPM]":"36.5","Tissue RNA - pons [nTPM]":"5.4","Tissue RNA - prostate [nTPM]":"9.1","Tissue RNA - rectum [nTPM]":"18.2","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"17.3","Tissue RNA - seminal vesicle [nTPM]":"13.7","Tissue RNA - skeletal muscle [nTPM]":"10.8","Tissue RNA - skin 1 [nTPM]":"25.5","Tissue RNA - small intestine [nTPM]":"13.7","Tissue RNA - smooth muscle [nTPM]":"23.4","Tissue RNA - spinal cord [nTPM]":"3.3","Tissue RNA - spleen [nTPM]":"40.6","Tissue RNA - stomach 1 [nTPM]":"15.7","Tissue RNA - testis [nTPM]":"3.7","Tissue RNA - thalamus [nTPM]":"4.7","Tissue RNA - thymus [nTPM]":"5.9","Tissue RNA - thyroid gland [nTPM]":"17.9","Tissue RNA - tongue [nTPM]":"18.9","Tissue RNA - tonsil [nTPM]":"7.2","Tissue RNA - urinary bladder [nTPM]":"128.5","Tissue RNA - vagina [nTPM]":"16.2","Tissue RNA - white matter [nTPM]":"4.7","Cell RNA - A-431 [nTPM]":"171.1","Cell RNA - A549 [nTPM]":"88.9","Cell RNA - AF22 [nTPM]":"36.8","Cell RNA - AN3-CA [nTPM]":"1.7","Cell RNA - ASC diff [nTPM]":"3.1","Cell RNA - ASC TERT1 [nTPM]":"59.5","Cell RNA - BEWO [nTPM]":"2.0","Cell RNA - BJ [nTPM]":"101.9","Cell RNA - BJ hTERT+ [nTPM]":"461.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"40.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"62.2","Cell RNA - CACO-2 [nTPM]":"2.3","Cell RNA - CAPAN-2 [nTPM]":"856.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"184.0","Cell RNA - fHDF\/TERT166 [nTPM]":"14.5","Cell RNA - GAMG [nTPM]":"416.9","Cell RNA - HaCaT [nTPM]":"114.1","Cell RNA - HAP1 [nTPM]":"0.9","Cell RNA - HBEC3-KT [nTPM]":"165.8","Cell RNA - HBF TERT88 [nTPM]":"44.8","Cell RNA - HDLM-2 [nTPM]":"9.9","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"4.4","Cell RNA - Hep G2 [nTPM]":"1.7","Cell RNA - HHSteC [nTPM]":"72.6","Cell RNA - HL-60 [nTPM]":"15.6","Cell RNA - HMC-1 [nTPM]":"32.3","Cell RNA - HSkMC [nTPM]":"158.7","Cell RNA - hTCEpi [nTPM]":"20.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"271.4","Cell RNA - hTERT-HME1 [nTPM]":"103.7","Cell RNA - hTERT-RPE1 [nTPM]":"447.0","Cell RNA - HUVEC TERT2 [nTPM]":"114.7","Cell RNA - JURKAT [nTPM]":"1.0","Cell RNA - K-562 [nTPM]":"1.1","Cell RNA - Karpas-707 [nTPM]":"0.9","Cell RNA - LHCN-M2 [nTPM]":"822.4","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"22.7","Cell RNA - NTERA-2 [nTPM]":"10.8","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"244.5","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"112.6","Cell RNA - RPMI-8226 [nTPM]":"0.9","Cell RNA - RPTEC TERT1 [nTPM]":"3100.7","Cell RNA - RT4 [nTPM]":"130.6","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"4.0","Cell RNA - SK-MEL-30 [nTPM]":"2.4","Cell RNA - SuSa [nTPM]":"25.4","Cell RNA - T-47d [nTPM]":"1.2","Cell RNA - THP-1 [nTPM]":"22.9","Cell RNA - TIME [nTPM]":"300.6","Cell RNA - U-138 MG [nTPM]":"3.5","Cell RNA - U-2 OS [nTPM]":"20.3","Cell RNA - U-2197 [nTPM]":"21.6","Cell RNA - U-251 MG [nTPM]":"869.8","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"1.3","Cell RNA - U-698 [nTPM]":"1.6","Cell RNA - U-87 MG [nTPM]":"216.0","Cell RNA - U-937 [nTPM]":"25.5","Cell RNA - WM-115 [nTPM]":"1.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"1.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"2.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"2.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"2.5","Brain RNA - basal ganglia [nTPM]":"2.7","Brain RNA - cerebellum [nTPM]":"2.7","Brain RNA - cerebral cortex [nTPM]":"8.9","Brain RNA - hippocampal formation [nTPM]":"2.4","Brain RNA - hypothalamus [nTPM]":"2.9","Brain RNA - medulla oblongata [nTPM]":"3.8","Brain RNA - midbrain [nTPM]":"2.9","Brain RNA - pons [nTPM]":"5.4","Brain RNA - spinal cord [nTPM]":"3.3","Brain RNA - thalamus [nTPM]":"4.7","Brain RNA - white matter [nTPM]":"4.7","Single Cell Type RNA - Adipocytes [nTPM]":"29.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"1.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"37.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"635.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"237.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.9","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"103.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"28.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"68.4","Single Cell Type RNA - Ductal cells [nTPM]":"62.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"50.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.2","Single Cell Type RNA - Endothelial cells [nTPM]":"46.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.5","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.7","Single Cell Type RNA - Fibroblasts [nTPM]":"69.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"68.9","Single Cell Type RNA - granulocytes [nTPM]":"31.1","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"39.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"140.4","Single Cell Type RNA - Kupffer cells [nTPM]":"4.0","Single Cell Type RNA - Langerhans cells [nTPM]":"33.1","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"53.4","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"23.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"613.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"695.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"35.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"65.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"60.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"29.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.5","Single Cell Type RNA - T-cells [nTPM]":"4.7","Single Cell Type RNA - Theca cells [nTPM]":"0.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.7","Single Cell Type RNA - Urothelial cells [nTPM]":"869.6"},{"Gene":"PLCB1","Gene synonym":["KIAA0581","PLC-I","PLC154"],"Ensembl":"ENSG00000182621","Gene description":"Phospholipase C beta 1","Uniprot":["Q9NQ66"],"Chromosome":"20","Position":"8077251-8968360","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase","Transducer"],"Disease involvement":["Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"74.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"563.5","Excitatory neurons":"2569.1","Inhibitory neurons":"1774.0","Oligodendrocyte precursor cells":"783.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"74.3"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"45.5","Hep G2":"68.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004275","CAB005334","HPA034743","HPA057910"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6600","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB004275":"AB_628118","CAB005334":"AB_632196","HPA034743":"AB_2674311","HPA057910":"AB_2683552"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.3","Tissue RNA - adrenal gland [nTPM]":"8.9","Tissue RNA - amygdala [nTPM]":"11.7","Tissue RNA - appendix [nTPM]":"5.7","Tissue RNA - basal ganglia [nTPM]":"52.3","Tissue RNA - bone marrow [nTPM]":"4.8","Tissue RNA - breast [nTPM]":"7.6","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"74.3","Tissue RNA - cervix [nTPM]":"8.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"18.1","Tissue RNA - duodenum [nTPM]":"7.2","Tissue RNA - endometrium 1 [nTPM]":"9.3","Tissue RNA - epididymis [nTPM]":"3.5","Tissue RNA - esophagus [nTPM]":"5.4","Tissue RNA - fallopian tube [nTPM]":"9.6","Tissue RNA - gallbladder [nTPM]":"8.5","Tissue RNA - heart muscle [nTPM]":"11.7","Tissue RNA - hippocampal formation [nTPM]":"17.4","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"13.2","Tissue RNA - liver [nTPM]":"4.3","Tissue RNA - lung [nTPM]":"5.0","Tissue RNA - lymph node [nTPM]":"1.8","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"3.7","Tissue RNA - pancreas [nTPM]":"14.7","Tissue RNA - parathyroid gland [nTPM]":"44.3","Tissue RNA - pituitary gland [nTPM]":"4.3","Tissue RNA - placenta [nTPM]":"19.6","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"13.4","Tissue RNA - rectum [nTPM]":"4.1","Tissue RNA - retina [nTPM]":"7.1","Tissue RNA - salivary gland [nTPM]":"29.0","Tissue RNA - seminal vesicle [nTPM]":"18.8","Tissue RNA - skeletal muscle [nTPM]":"14.4","Tissue RNA - skin 1 [nTPM]":"2.6","Tissue RNA - small intestine [nTPM]":"5.7","Tissue RNA - smooth muscle [nTPM]":"8.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"3.6","Tissue RNA - stomach 1 [nTPM]":"8.0","Tissue RNA - testis [nTPM]":"3.0","Tissue RNA - thalamus [nTPM]":"9.8","Tissue RNA - thymus [nTPM]":"6.8","Tissue RNA - thyroid gland [nTPM]":"3.8","Tissue RNA - tongue [nTPM]":"11.0","Tissue RNA - tonsil [nTPM]":"0.9","Tissue RNA - urinary bladder [nTPM]":"15.9","Tissue RNA - vagina [nTPM]":"6.7","Tissue RNA - white matter [nTPM]":"23.8","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"1.2","Cell RNA - AF22 [nTPM]":"4.8","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"8.7","Cell RNA - ASC TERT1 [nTPM]":"16.1","Cell RNA - BEWO [nTPM]":"6.3","Cell RNA - BJ [nTPM]":"20.2","Cell RNA - BJ hTERT+ [nTPM]":"13.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.1","Cell RNA - CACO-2 [nTPM]":"45.5","Cell RNA - CAPAN-2 [nTPM]":"5.0","Cell RNA - Daudi [nTPM]":"2.2","Cell RNA - EFO-21 [nTPM]":"8.2","Cell RNA - fHDF\/TERT166 [nTPM]":"3.9","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"3.7","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"3.8","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"4.4","Cell RNA - HEL [nTPM]":"1.0","Cell RNA - HeLa [nTPM]":"3.5","Cell RNA - Hep G2 [nTPM]":"68.7","Cell RNA - HHSteC [nTPM]":"2.2","Cell RNA - HL-60 [nTPM]":"1.1","Cell RNA - HMC-1 [nTPM]":"0.7","Cell RNA - HSkMC [nTPM]":"1.1","Cell RNA - hTCEpi [nTPM]":"0.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"6.5","Cell RNA - HUVEC TERT2 [nTPM]":"10.6","Cell RNA - JURKAT [nTPM]":"13.0","Cell RNA - K-562 [nTPM]":"7.1","Cell RNA - Karpas-707 [nTPM]":"26.0","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"6.2","Cell RNA - MOLT-4 [nTPM]":"1.0","Cell RNA - NB-4 [nTPM]":"3.3","Cell RNA - NTERA-2 [nTPM]":"15.0","Cell RNA - OE19 [nTPM]":"10.6","Cell RNA - PC-3 [nTPM]":"6.6","Cell RNA - REH [nTPM]":"14.7","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"12.1","Cell RNA - RPTEC TERT1 [nTPM]":"4.0","Cell RNA - RT4 [nTPM]":"16.8","Cell RNA - SCLC-21H [nTPM]":"16.9","Cell RNA - SH-SY5Y [nTPM]":"7.2","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"4.1","Cell RNA - SK-MEL-30 [nTPM]":"0.9","Cell RNA - SuSa [nTPM]":"17.1","Cell RNA - T-47d [nTPM]":"19.9","Cell RNA - THP-1 [nTPM]":"6.6","Cell RNA - TIME [nTPM]":"1.9","Cell RNA - U-138 MG [nTPM]":"16.8","Cell RNA - U-2 OS [nTPM]":"7.5","Cell RNA - U-2197 [nTPM]":"1.3","Cell RNA - U-251 MG [nTPM]":"12.7","Cell RNA - U-266\/70 [nTPM]":"19.4","Cell RNA - U-266\/84 [nTPM]":"24.5","Cell RNA - U-698 [nTPM]":"33.9","Cell RNA - U-87 MG [nTPM]":"8.6","Cell RNA - U-937 [nTPM]":"12.6","Cell RNA - WM-115 [nTPM]":"29.5","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"1.2","Blood RNA - gdT-cell [nTPM]":"1.4","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"2.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"11.7","Brain RNA - basal ganglia [nTPM]":"52.3","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"74.3","Brain RNA - hippocampal formation [nTPM]":"17.4","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"9.8","Brain RNA - white matter [nTPM]":"23.8","Single Cell Type RNA - Adipocytes [nTPM]":"74.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.4","Single Cell Type RNA - Astrocytes [nTPM]":"563.5","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"7.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"26.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"2.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.4","Single Cell Type RNA - dendritic cells [nTPM]":"16.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"1.2","Single Cell Type RNA - Early spermatids [nTPM]":"9.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"42.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.1","Single Cell Type RNA - Endothelial cells [nTPM]":"54.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"6.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"2569.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.8","Single Cell Type RNA - Fibroblasts [nTPM]":"25.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"83.6","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.4","Single Cell Type RNA - Hepatocytes [nTPM]":"2.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.8","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1774.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"8.2","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"4.3","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"9.1","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"211.7","Single Cell Type RNA - monocytes [nTPM]":"12.2","Single Cell Type RNA - Muller glia cells [nTPM]":"18.2","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"783.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"34.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.5","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"6.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.3","Single Cell Type RNA - Spermatocytes [nTPM]":"4.7","Single Cell Type RNA - Spermatogonia [nTPM]":"5.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.8","Single Cell Type RNA - T-cells [nTPM]":"15.4","Single Cell Type RNA - Theca cells [nTPM]":"1.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.2","Single Cell Type RNA - Urothelial cells [nTPM]":"18.9"},{"Gene":"PLCB4","Gene synonym":[],"Ensembl":"ENSG00000101333","Gene description":"Phospholipase C beta 4","Uniprot":["Q15147"],"Chromosome":"20","Position":"9068763-9481242","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"55.6","salivary gland":"57.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"105.9","Horizontal cells":"164.9","Inhibitory neurons":"113.8","Microglial cells":"183.6","Oligodendrocyte precursor cells":"168.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"23.5"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"55.6"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"18","RNA blood cell specific nTPM":{"plasmacytoid DC":"3.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"dendritic cells":"3.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"fHDF\/TERT166":"91.4","hTERT-HME1":"45.9","LHCN-M2":"77.6","OE19":"48.2","RPTEC TERT1":"96.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007951"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Microtubules"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA007951":"AB_2667944"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.11e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.3","Tissue RNA - adrenal gland [nTPM]":"7.2","Tissue RNA - amygdala [nTPM]":"8.6","Tissue RNA - appendix [nTPM]":"3.4","Tissue RNA - basal ganglia [nTPM]":"3.7","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"7.0","Tissue RNA - cerebellum [nTPM]":"55.6","Tissue RNA - cerebral cortex [nTPM]":"6.3","Tissue RNA - cervix [nTPM]":"4.6","Tissue RNA - choroid plexus [nTPM]":"31.0","Tissue RNA - colon [nTPM]":"20.5","Tissue RNA - duodenum [nTPM]":"2.6","Tissue RNA - endometrium 1 [nTPM]":"8.2","Tissue RNA - epididymis [nTPM]":"24.4","Tissue RNA - esophagus [nTPM]":"9.0","Tissue RNA - fallopian tube [nTPM]":"15.0","Tissue RNA - gallbladder [nTPM]":"5.9","Tissue RNA - heart muscle [nTPM]":"17.9","Tissue RNA - hippocampal formation [nTPM]":"2.5","Tissue RNA - hypothalamus [nTPM]":"10.8","Tissue RNA - kidney [nTPM]":"3.0","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"5.4","Tissue RNA - lymph node [nTPM]":"1.7","Tissue RNA - medulla oblongata [nTPM]":"13.4","Tissue RNA - midbrain [nTPM]":"17.8","Tissue RNA - ovary [nTPM]":"2.1","Tissue RNA - pancreas [nTPM]":"2.1","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"8.2","Tissue RNA - placenta [nTPM]":"6.5","Tissue RNA - pons [nTPM]":"12.0","Tissue RNA - prostate [nTPM]":"9.7","Tissue RNA - rectum [nTPM]":"17.9","Tissue RNA - retina [nTPM]":"15.1","Tissue RNA - salivary gland [nTPM]":"57.4","Tissue RNA - seminal vesicle [nTPM]":"6.1","Tissue RNA - skeletal muscle [nTPM]":"2.7","Tissue RNA - skin 1 [nTPM]":"4.6","Tissue RNA - small intestine [nTPM]":"4.2","Tissue RNA - smooth muscle [nTPM]":"9.1","Tissue RNA - spinal cord [nTPM]":"5.3","Tissue RNA - spleen [nTPM]":"1.3","Tissue RNA - stomach 1 [nTPM]":"14.4","Tissue RNA - testis [nTPM]":"2.4","Tissue RNA - thalamus [nTPM]":"23.3","Tissue RNA - thymus [nTPM]":"4.5","Tissue RNA - thyroid gland [nTPM]":"32.7","Tissue RNA - tongue [nTPM]":"6.8","Tissue RNA - tonsil [nTPM]":"2.3","Tissue RNA - urinary bladder [nTPM]":"8.2","Tissue RNA - vagina [nTPM]":"5.3","Tissue RNA - white matter [nTPM]":"6.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"15.1","Cell RNA - AF22 [nTPM]":"7.9","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"35.8","Cell RNA - BJ hTERT+ [nTPM]":"9.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.1","Cell RNA - CACO-2 [nTPM]":"3.4","Cell RNA - CAPAN-2 [nTPM]":"2.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.6","Cell RNA - fHDF\/TERT166 [nTPM]":"91.4","Cell RNA - GAMG [nTPM]":"39.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"2.3","Cell RNA - HBEC3-KT [nTPM]":"7.6","Cell RNA - HBF TERT88 [nTPM]":"14.7","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"5.3","Cell RNA - HEL [nTPM]":"3.8","Cell RNA - HeLa [nTPM]":"5.7","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"1.6","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"2.3","Cell RNA - hTCEpi [nTPM]":"3.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.7","Cell RNA - hTERT-HME1 [nTPM]":"45.9","Cell RNA - hTERT-RPE1 [nTPM]":"18.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"4.3","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"77.6","Cell RNA - MCF7 [nTPM]":"5.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"8.8","Cell RNA - OE19 [nTPM]":"48.2","Cell RNA - PC-3 [nTPM]":"10.4","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"96.9","Cell RNA - RT4 [nTPM]":"5.8","Cell RNA - SCLC-21H [nTPM]":"25.5","Cell RNA - SH-SY5Y [nTPM]":"18.4","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"23.8","Cell RNA - SK-MEL-30 [nTPM]":"15.1","Cell RNA - SuSa [nTPM]":"10.5","Cell RNA - T-47d [nTPM]":"19.2","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.5","Cell RNA - U-138 MG [nTPM]":"11.2","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"1.2","Cell RNA - U-251 MG [nTPM]":"14.2","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.7","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"3.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"8.6","Brain RNA - basal ganglia [nTPM]":"3.7","Brain RNA - cerebellum [nTPM]":"55.6","Brain RNA - cerebral cortex [nTPM]":"6.3","Brain RNA - hippocampal formation [nTPM]":"2.5","Brain RNA - hypothalamus [nTPM]":"10.8","Brain RNA - medulla oblongata [nTPM]":"13.4","Brain RNA - midbrain [nTPM]":"17.8","Brain RNA - pons [nTPM]":"12.0","Brain RNA - spinal cord [nTPM]":"5.3","Brain RNA - thalamus [nTPM]":"23.3","Brain RNA - white matter [nTPM]":"6.5","Single Cell Type RNA - Adipocytes [nTPM]":"37.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"60.1","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"82.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"72.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"8.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"4.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.7","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"46.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.6","Single Cell Type RNA - Endothelial cells [nTPM]":"40.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"42.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"105.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"9.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"53.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"36.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"164.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"113.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"36.4","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"2.1","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"183.6","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"2.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"168.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.1","Single Cell Type RNA - Paneth cells [nTPM]":"9.7","Single Cell Type RNA - Peritubular cells [nTPM]":"20.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"39.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"36.0","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"2.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"1.4","Single Cell Type RNA - Theca cells [nTPM]":"4.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"40.4","Single Cell Type RNA - Urothelial cells [nTPM]":"2.5"},{"Gene":"PLCD1","Gene synonym":[],"Ensembl":"ENSG00000187091","Gene description":"Phospholipase C delta 1","Uniprot":["P51178"],"Chromosome":"3","Position":"38007496-38029642","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"89.5","Theca cells":"53.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"25.3","fHDF\/TERT166":"26.3","hTCEpi":"31.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009913","HPA020107","HPA021677"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"CAB009913":"AB_2163388","HPA020107":"AB_1855318","HPA021677":"AB_1855319"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.67e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.25e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.71e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.88e-2"},"Tissue RNA - adipose tissue [nTPM]":"14.8","Tissue RNA - adrenal gland [nTPM]":"12.9","Tissue RNA - amygdala [nTPM]":"14.3","Tissue RNA - appendix [nTPM]":"4.6","Tissue RNA - basal ganglia [nTPM]":"16.1","Tissue RNA - bone marrow [nTPM]":"4.3","Tissue RNA - breast [nTPM]":"10.6","Tissue RNA - cerebellum [nTPM]":"15.4","Tissue RNA - cerebral cortex [nTPM]":"15.6","Tissue RNA - cervix [nTPM]":"15.9","Tissue RNA - choroid plexus [nTPM]":"9.7","Tissue RNA - colon [nTPM]":"15.7","Tissue RNA - duodenum [nTPM]":"4.9","Tissue RNA - endometrium 1 [nTPM]":"11.5","Tissue RNA - epididymis [nTPM]":"4.2","Tissue RNA - esophagus [nTPM]":"26.2","Tissue RNA - fallopian tube [nTPM]":"9.8","Tissue RNA - gallbladder [nTPM]":"5.6","Tissue RNA - heart muscle [nTPM]":"7.2","Tissue RNA - hippocampal formation [nTPM]":"12.8","Tissue RNA - hypothalamus [nTPM]":"19.0","Tissue RNA - kidney [nTPM]":"10.1","Tissue RNA - liver [nTPM]":"5.4","Tissue RNA - lung [nTPM]":"11.3","Tissue RNA - lymph node [nTPM]":"6.6","Tissue RNA - medulla oblongata [nTPM]":"20.3","Tissue RNA - midbrain [nTPM]":"18.5","Tissue RNA - ovary [nTPM]":"12.7","Tissue RNA - pancreas [nTPM]":"6.0","Tissue RNA - parathyroid gland [nTPM]":"3.9","Tissue RNA - pituitary gland [nTPM]":"9.3","Tissue RNA - placenta [nTPM]":"3.8","Tissue RNA - pons [nTPM]":"19.6","Tissue RNA - prostate [nTPM]":"9.1","Tissue RNA - rectum [nTPM]":"10.1","Tissue RNA - retina [nTPM]":"2.8","Tissue RNA - salivary gland [nTPM]":"13.0","Tissue RNA - seminal vesicle [nTPM]":"8.8","Tissue RNA - skeletal muscle [nTPM]":"2.9","Tissue RNA - skin 1 [nTPM]":"18.5","Tissue RNA - small intestine [nTPM]":"8.3","Tissue RNA - smooth muscle [nTPM]":"5.6","Tissue RNA - spinal cord [nTPM]":"19.4","Tissue RNA - spleen [nTPM]":"7.2","Tissue RNA - stomach 1 [nTPM]":"8.3","Tissue RNA - testis [nTPM]":"32.6","Tissue RNA - thalamus [nTPM]":"16.9","Tissue RNA - thymus [nTPM]":"9.1","Tissue RNA - thyroid gland [nTPM]":"8.3","Tissue RNA - tongue [nTPM]":"4.1","Tissue RNA - tonsil [nTPM]":"6.6","Tissue RNA - urinary bladder [nTPM]":"15.7","Tissue RNA - vagina [nTPM]":"19.0","Tissue RNA - white matter [nTPM]":"21.9","Cell RNA - A-431 [nTPM]":"1.0","Cell RNA - A549 [nTPM]":"2.7","Cell RNA - AF22 [nTPM]":"9.4","Cell RNA - AN3-CA [nTPM]":"2.6","Cell RNA - ASC diff [nTPM]":"25.3","Cell RNA - ASC TERT1 [nTPM]":"22.2","Cell RNA - BEWO [nTPM]":"2.8","Cell RNA - BJ [nTPM]":"2.8","Cell RNA - BJ hTERT+ [nTPM]":"11.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.4","Cell RNA - CACO-2 [nTPM]":"1.0","Cell RNA - CAPAN-2 [nTPM]":"2.3","Cell RNA - Daudi [nTPM]":"0.6","Cell RNA - EFO-21 [nTPM]":"1.4","Cell RNA - fHDF\/TERT166 [nTPM]":"26.3","Cell RNA - GAMG [nTPM]":"2.9","Cell RNA - HaCaT [nTPM]":"15.0","Cell RNA - HAP1 [nTPM]":"4.8","Cell RNA - HBEC3-KT [nTPM]":"3.0","Cell RNA - HBF TERT88 [nTPM]":"1.3","Cell RNA - HDLM-2 [nTPM]":"3.9","Cell RNA - HEK 293 [nTPM]":"1.2","Cell RNA - HEL [nTPM]":"0.5","Cell RNA - HeLa [nTPM]":"1.7","Cell RNA - Hep G2 [nTPM]":"4.7","Cell RNA - HHSteC [nTPM]":"14.7","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.6","Cell RNA - HSkMC [nTPM]":"18.0","Cell RNA - hTCEpi [nTPM]":"31.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.9","Cell RNA - hTERT-HME1 [nTPM]":"1.7","Cell RNA - hTERT-RPE1 [nTPM]":"9.4","Cell RNA - HUVEC TERT2 [nTPM]":"8.2","Cell RNA - JURKAT [nTPM]":"2.2","Cell RNA - K-562 [nTPM]":"16.3","Cell RNA - Karpas-707 [nTPM]":"1.3","Cell RNA - LHCN-M2 [nTPM]":"9.6","Cell RNA - MCF7 [nTPM]":"1.2","Cell RNA - MOLT-4 [nTPM]":"2.2","Cell RNA - NB-4 [nTPM]":"1.1","Cell RNA - NTERA-2 [nTPM]":"2.4","Cell RNA - OE19 [nTPM]":"5.5","Cell RNA - PC-3 [nTPM]":"2.7","Cell RNA - REH [nTPM]":"0.9","Cell RNA - RH-30 [nTPM]":"1.3","Cell RNA - RPMI-8226 [nTPM]":"3.6","Cell RNA - RPTEC TERT1 [nTPM]":"5.1","Cell RNA - RT4 [nTPM]":"5.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"2.6","Cell RNA - SiHa [nTPM]":"0.8","Cell RNA - SK-BR-3 [nTPM]":"12.4","Cell RNA - SK-MEL-30 [nTPM]":"3.2","Cell RNA - SuSa [nTPM]":"3.1","Cell RNA - T-47d [nTPM]":"2.7","Cell RNA - THP-1 [nTPM]":"1.2","Cell RNA - TIME [nTPM]":"4.4","Cell RNA - U-138 MG [nTPM]":"2.5","Cell RNA - U-2 OS [nTPM]":"6.3","Cell RNA - U-2197 [nTPM]":"6.7","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"5.2","Cell RNA - U-266\/84 [nTPM]":"2.2","Cell RNA - U-698 [nTPM]":"0.6","Cell RNA - U-87 MG [nTPM]":"6.4","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"1.3","Blood RNA - basophil [nTPM]":"14.6","Blood RNA - classical monocyte [nTPM]":"2.7","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"13.0","Blood RNA - intermediate monocyte [nTPM]":"3.7","Blood RNA - MAIT T-cell [nTPM]":"15.2","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"16.9","Blood RNA - memory CD8 T-cell [nTPM]":"12.8","Blood RNA - myeloid DC [nTPM]":"3.8","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"10.1","Blood RNA - naive CD8 T-cell [nTPM]":"7.9","Blood RNA - neutrophil [nTPM]":"9.9","Blood RNA - NK-cell [nTPM]":"5.9","Blood RNA - non-classical monocyte [nTPM]":"2.2","Blood RNA - plasmacytoid DC [nTPM]":"2.0","Blood RNA - T-reg [nTPM]":"16.6","Blood RNA - total PBMC [nTPM]":"7.4","Brain RNA - amygdala [nTPM]":"14.3","Brain RNA - basal ganglia [nTPM]":"16.1","Brain RNA - cerebellum [nTPM]":"15.4","Brain RNA - cerebral cortex [nTPM]":"15.6","Brain RNA - hippocampal formation [nTPM]":"12.8","Brain RNA - hypothalamus [nTPM]":"19.0","Brain RNA - medulla oblongata [nTPM]":"20.3","Brain RNA - midbrain [nTPM]":"18.5","Brain RNA - pons [nTPM]":"19.6","Brain RNA - spinal cord [nTPM]":"19.4","Brain RNA - thalamus [nTPM]":"16.9","Brain RNA - white matter [nTPM]":"21.9","Single Cell Type RNA - Adipocytes [nTPM]":"5.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.5","Single Cell Type RNA - Astrocytes [nTPM]":"22.9","Single Cell Type RNA - B-cells [nTPM]":"3.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"7.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.8","Single Cell Type RNA - dendritic cells [nTPM]":"4.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"89.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.4","Single Cell Type RNA - Early spermatids [nTPM]":"1.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.3","Single Cell Type RNA - Endothelial cells [nTPM]":"8.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.9","Single Cell Type RNA - Erythroid cells [nTPM]":"3.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.1","Single Cell Type RNA - Fibroblasts [nTPM]":"10.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.8","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"3.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.0","Single Cell Type RNA - Hepatocytes [nTPM]":"4.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.3","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"3.8","Single Cell Type RNA - Langerhans cells [nTPM]":"14.5","Single Cell Type RNA - Late spermatids [nTPM]":"3.6","Single Cell Type RNA - Leydig cells [nTPM]":"12.8","Single Cell Type RNA - Macrophages [nTPM]":"4.3","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"3.4","Single Cell Type RNA - Muller glia cells [nTPM]":"13.3","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.1","Single Cell Type RNA - Paneth cells [nTPM]":"34.7","Single Cell Type RNA - Peritubular cells [nTPM]":"14.3","Single Cell Type RNA - Plasma cells [nTPM]":"5.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.2","Single Cell Type RNA - Spermatocytes [nTPM]":"3.1","Single Cell Type RNA - Spermatogonia [nTPM]":"3.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"7.4","Single Cell Type RNA - Theca cells [nTPM]":"53.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.3","Single Cell Type RNA - Urothelial cells [nTPM]":"14.7"},{"Gene":"PLCE1","Gene synonym":["KIAA1516","NPHS3","PLCE"],"Ensembl":"ENSG00000138193","Gene description":"Phospholipase C epsilon 1","Uniprot":["Q9P212"],"Chromosome":"10","Position":"93993931-94332823","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Guanine-nucleotide releasing factor","Hydrolase","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"70.5","Astrocytes":"69.5","Distal enterocytes":"79.6","Inhibitory neurons":"83.9","Muller glia cells":"82.7","Oligodendrocyte precursor cells":"123.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RT4":"10.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015597","HPA015598"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA015597":"AB_1855321","HPA015598":"AB_1855322"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.8","Tissue RNA - adrenal gland [nTPM]":"2.6","Tissue RNA - amygdala [nTPM]":"4.5","Tissue RNA - appendix [nTPM]":"2.8","Tissue RNA - basal ganglia [nTPM]":"4.1","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"2.7","Tissue RNA - cerebellum [nTPM]":"3.1","Tissue RNA - cerebral cortex [nTPM]":"5.6","Tissue RNA - cervix [nTPM]":"8.0","Tissue RNA - choroid plexus [nTPM]":"7.0","Tissue RNA - colon [nTPM]":"12.6","Tissue RNA - duodenum [nTPM]":"4.0","Tissue RNA - endometrium 1 [nTPM]":"9.0","Tissue RNA - epididymis [nTPM]":"5.3","Tissue RNA - esophagus [nTPM]":"1.7","Tissue RNA - fallopian tube [nTPM]":"4.4","Tissue RNA - gallbladder [nTPM]":"2.5","Tissue RNA - heart muscle [nTPM]":"12.4","Tissue RNA - hippocampal formation [nTPM]":"3.9","Tissue RNA - hypothalamus [nTPM]":"4.7","Tissue RNA - kidney [nTPM]":"8.4","Tissue RNA - liver [nTPM]":"0.7","Tissue RNA - lung [nTPM]":"7.3","Tissue RNA - lymph node [nTPM]":"0.7","Tissue RNA - medulla oblongata [nTPM]":"3.9","Tissue RNA - midbrain [nTPM]":"4.8","Tissue RNA - ovary [nTPM]":"3.9","Tissue RNA - pancreas [nTPM]":"14.7","Tissue RNA - parathyroid gland [nTPM]":"0.8","Tissue RNA - pituitary gland [nTPM]":"4.4","Tissue RNA - placenta [nTPM]":"2.9","Tissue RNA - pons [nTPM]":"4.0","Tissue RNA - prostate [nTPM]":"3.8","Tissue RNA - rectum [nTPM]":"7.5","Tissue RNA - retina [nTPM]":"7.3","Tissue RNA - salivary gland [nTPM]":"2.3","Tissue RNA - seminal vesicle [nTPM]":"5.4","Tissue RNA - skeletal muscle [nTPM]":"4.1","Tissue RNA - skin 1 [nTPM]":"1.1","Tissue RNA - small intestine [nTPM]":"5.2","Tissue RNA - smooth muscle [nTPM]":"4.2","Tissue RNA - spinal cord [nTPM]":"3.2","Tissue RNA - spleen [nTPM]":"6.2","Tissue RNA - stomach 1 [nTPM]":"8.3","Tissue RNA - testis [nTPM]":"2.0","Tissue RNA - thalamus [nTPM]":"5.4","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"9.8","Tissue RNA - tongue [nTPM]":"6.3","Tissue RNA - tonsil [nTPM]":"0.6","Tissue RNA - urinary bladder [nTPM]":"5.6","Tissue RNA - vagina [nTPM]":"5.6","Tissue RNA - white matter [nTPM]":"4.2","Cell RNA - A-431 [nTPM]":"4.0","Cell RNA - A549 [nTPM]":"6.7","Cell RNA - AF22 [nTPM]":"1.8","Cell RNA - AN3-CA [nTPM]":"1.1","Cell RNA - ASC diff [nTPM]":"0.7","Cell RNA - ASC TERT1 [nTPM]":"3.2","Cell RNA - BEWO [nTPM]":"1.9","Cell RNA - BJ [nTPM]":"2.8","Cell RNA - BJ hTERT+ [nTPM]":"0.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"5.3","Cell RNA - CAPAN-2 [nTPM]":"1.3","Cell RNA - Daudi [nTPM]":"0.8","Cell RNA - EFO-21 [nTPM]":"1.3","Cell RNA - fHDF\/TERT166 [nTPM]":"2.3","Cell RNA - GAMG [nTPM]":"1.3","Cell RNA - HaCaT [nTPM]":"2.6","Cell RNA - HAP1 [nTPM]":"2.2","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"0.6","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"2.3","Cell RNA - HEL [nTPM]":"0.5","Cell RNA - HeLa [nTPM]":"4.0","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.9","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"1.8","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"6.8","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"0.5","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"4.2","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.8","Cell RNA - NB-4 [nTPM]":"0.9","Cell RNA - NTERA-2 [nTPM]":"0.7","Cell RNA - OE19 [nTPM]":"7.9","Cell RNA - PC-3 [nTPM]":"5.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"3.9","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"10.3","Cell RNA - SCLC-21H [nTPM]":"0.9","Cell RNA - SH-SY5Y [nTPM]":"1.5","Cell RNA - SiHa [nTPM]":"3.3","Cell RNA - SK-BR-3 [nTPM]":"3.6","Cell RNA - SK-MEL-30 [nTPM]":"0.7","Cell RNA - SuSa [nTPM]":"4.1","Cell RNA - T-47d [nTPM]":"3.5","Cell RNA - THP-1 [nTPM]":"0.6","Cell RNA - TIME [nTPM]":"0.6","Cell RNA - U-138 MG [nTPM]":"3.0","Cell RNA - U-2 OS [nTPM]":"5.9","Cell RNA - U-2197 [nTPM]":"2.0","Cell RNA - U-251 MG [nTPM]":"4.4","Cell RNA - U-266\/70 [nTPM]":"0.6","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"3.5","Cell RNA - U-937 [nTPM]":"1.1","Cell RNA - WM-115 [nTPM]":"2.2","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"4.5","Brain RNA - basal ganglia [nTPM]":"4.1","Brain RNA - cerebellum [nTPM]":"3.1","Brain RNA - cerebral cortex [nTPM]":"5.6","Brain RNA - hippocampal formation [nTPM]":"3.9","Brain RNA - hypothalamus [nTPM]":"4.7","Brain RNA - medulla oblongata [nTPM]":"3.9","Brain RNA - midbrain [nTPM]":"4.8","Brain RNA - pons [nTPM]":"4.0","Brain RNA - spinal cord [nTPM]":"3.2","Brain RNA - thalamus [nTPM]":"5.4","Brain RNA - white matter [nTPM]":"4.2","Single Cell Type RNA - Adipocytes [nTPM]":"8.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"70.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.4","Single Cell Type RNA - Astrocytes [nTPM]":"69.5","Single Cell Type RNA - B-cells [nTPM]":"7.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"12.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"34.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"12.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.7","Single Cell Type RNA - dendritic cells [nTPM]":"2.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"79.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.1","Single Cell Type RNA - Early spermatids [nTPM]":"20.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"26.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.4","Single Cell Type RNA - Endothelial cells [nTPM]":"9.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.5","Single Cell Type RNA - Fibroblasts [nTPM]":"15.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"29.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"7.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.2","Single Cell Type RNA - Hepatocytes [nTPM]":"1.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.7","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"83.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.7","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"2.4","Single Cell Type RNA - Langerhans cells [nTPM]":"5.2","Single Cell Type RNA - Late spermatids [nTPM]":"5.3","Single Cell Type RNA - Leydig cells [nTPM]":"12.2","Single Cell Type RNA - Macrophages [nTPM]":"1.3","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"1.2","Single Cell Type RNA - Muller glia cells [nTPM]":"82.7","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"123.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.2","Single Cell Type RNA - Paneth cells [nTPM]":"54.8","Single Cell Type RNA - Peritubular cells [nTPM]":"23.3","Single Cell Type RNA - Plasma cells [nTPM]":"0.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"37.7","Single Cell Type RNA - Spermatocytes [nTPM]":"3.7","Single Cell Type RNA - Spermatogonia [nTPM]":"8.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - T-cells [nTPM]":"4.3","Single Cell Type RNA - Theca cells [nTPM]":"3.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"41.1","Single Cell Type RNA - Urothelial cells [nTPM]":"10.5"},{"Gene":"PLCG2","Gene synonym":[],"Ensembl":"ENSG00000197943","Gene description":"Phospholipase C gamma 2","Uniprot":["P16885"],"Chromosome":"16","Position":"81739097-81962685","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase","Transducer"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"706.3","choroid plexus":"347.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"187.0","Bipolar cells":"224.8","Muller glia cells":"221.7","Rod photoreceptor cells":"196.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"9.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"183.3","HMC-1":"84.2","REH":"75.1","U-698":"403.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004280","HPA020099","HPA020100"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"8200","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB004280":"AB_628120","HPA020099":"AB_1855324","HPA020100":"AB_1855325"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.71e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.88e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-3"},"Tissue RNA - adipose tissue [nTPM]":"9.0","Tissue RNA - adrenal gland [nTPM]":"4.2","Tissue RNA - amygdala [nTPM]":"69.4","Tissue RNA - appendix [nTPM]":"33.0","Tissue RNA - basal ganglia [nTPM]":"141.3","Tissue RNA - bone marrow [nTPM]":"30.3","Tissue RNA - breast [nTPM]":"8.5","Tissue RNA - cerebellum [nTPM]":"706.3","Tissue RNA - cerebral cortex [nTPM]":"105.2","Tissue RNA - cervix [nTPM]":"5.0","Tissue RNA - choroid plexus [nTPM]":"347.5","Tissue RNA - colon [nTPM]":"8.6","Tissue RNA - duodenum [nTPM]":"17.3","Tissue RNA - endometrium 1 [nTPM]":"8.6","Tissue RNA - epididymis [nTPM]":"22.5","Tissue RNA - esophagus [nTPM]":"4.6","Tissue RNA - fallopian tube [nTPM]":"5.5","Tissue RNA - gallbladder [nTPM]":"13.4","Tissue RNA - heart muscle [nTPM]":"4.3","Tissue RNA - hippocampal formation [nTPM]":"40.1","Tissue RNA - hypothalamus [nTPM]":"122.6","Tissue RNA - kidney [nTPM]":"23.4","Tissue RNA - liver [nTPM]":"14.3","Tissue RNA - lung [nTPM]":"9.4","Tissue RNA - lymph node [nTPM]":"66.8","Tissue RNA - medulla oblongata [nTPM]":"301.3","Tissue RNA - midbrain [nTPM]":"122.7","Tissue RNA - ovary [nTPM]":"1.6","Tissue RNA - pancreas [nTPM]":"3.9","Tissue RNA - parathyroid gland [nTPM]":"2.8","Tissue RNA - pituitary gland [nTPM]":"1.2","Tissue RNA - placenta [nTPM]":"8.2","Tissue RNA - pons [nTPM]":"207.3","Tissue RNA - prostate [nTPM]":"2.8","Tissue RNA - rectum [nTPM]":"7.0","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"7.1","Tissue RNA - seminal vesicle [nTPM]":"3.4","Tissue RNA - skeletal muscle [nTPM]":"1.9","Tissue RNA - skin 1 [nTPM]":"4.0","Tissue RNA - small intestine [nTPM]":"19.4","Tissue RNA - smooth muscle [nTPM]":"8.8","Tissue RNA - spinal cord [nTPM]":"241.5","Tissue RNA - spleen [nTPM]":"34.8","Tissue RNA - stomach 1 [nTPM]":"8.7","Tissue RNA - testis [nTPM]":"2.0","Tissue RNA - thalamus [nTPM]":"283.3","Tissue RNA - thymus [nTPM]":"10.0","Tissue RNA - thyroid gland [nTPM]":"6.9","Tissue RNA - tongue [nTPM]":"3.6","Tissue RNA - tonsil [nTPM]":"72.0","Tissue RNA - urinary bladder [nTPM]":"10.1","Tissue RNA - vagina [nTPM]":"3.9","Tissue RNA - white matter [nTPM]":"437.2","Cell RNA - A-431 [nTPM]":"1.4","Cell RNA - A549 [nTPM]":"3.2","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"2.9","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"4.0","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.8","Cell RNA - CACO-2 [nTPM]":"0.9","Cell RNA - CAPAN-2 [nTPM]":"8.1","Cell RNA - Daudi [nTPM]":"183.3","Cell RNA - EFO-21 [nTPM]":"30.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"7.4","Cell RNA - HaCaT [nTPM]":"4.2","Cell RNA - HAP1 [nTPM]":"4.0","Cell RNA - HBEC3-KT [nTPM]":"0.5","Cell RNA - HBF TERT88 [nTPM]":"1.4","Cell RNA - HDLM-2 [nTPM]":"1.4","Cell RNA - HEK 293 [nTPM]":"2.1","Cell RNA - HEL [nTPM]":"22.1","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"1.2","Cell RNA - HL-60 [nTPM]":"22.3","Cell RNA - HMC-1 [nTPM]":"84.2","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"1.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.3","Cell RNA - hTERT-HME1 [nTPM]":"1.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"4.2","Cell RNA - JURKAT [nTPM]":"8.1","Cell RNA - K-562 [nTPM]":"2.5","Cell RNA - Karpas-707 [nTPM]":"15.0","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"5.7","Cell RNA - MOLT-4 [nTPM]":"2.6","Cell RNA - NB-4 [nTPM]":"55.5","Cell RNA - NTERA-2 [nTPM]":"3.1","Cell RNA - OE19 [nTPM]":"2.3","Cell RNA - PC-3 [nTPM]":"1.3","Cell RNA - REH [nTPM]":"75.1","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"23.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.5","Cell RNA - RT4 [nTPM]":"3.9","Cell RNA - SCLC-21H [nTPM]":"1.4","Cell RNA - SH-SY5Y [nTPM]":"0.4","Cell RNA - SiHa [nTPM]":"5.0","Cell RNA - SK-BR-3 [nTPM]":"1.6","Cell RNA - SK-MEL-30 [nTPM]":"1.5","Cell RNA - SuSa [nTPM]":"3.9","Cell RNA - T-47d [nTPM]":"3.3","Cell RNA - THP-1 [nTPM]":"67.7","Cell RNA - TIME [nTPM]":"1.1","Cell RNA - U-138 MG [nTPM]":"0.4","Cell RNA - U-2 OS [nTPM]":"3.2","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.6","Cell RNA - U-266\/70 [nTPM]":"35.2","Cell RNA - U-266\/84 [nTPM]":"61.4","Cell RNA - U-698 [nTPM]":"403.4","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"30.0","Cell RNA - WM-115 [nTPM]":"1.6","Blood RNA - basophil [nTPM]":"9.4","Blood RNA - classical monocyte [nTPM]":"12.1","Blood RNA - eosinophil [nTPM]":"76.2","Blood RNA - gdT-cell [nTPM]":"1.9","Blood RNA - intermediate monocyte [nTPM]":"16.1","Blood RNA - MAIT T-cell [nTPM]":"0.9","Blood RNA - memory B-cell [nTPM]":"51.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"2.9","Blood RNA - myeloid DC [nTPM]":"10.7","Blood RNA - naive B-cell [nTPM]":"49.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"65.7","Blood RNA - NK-cell [nTPM]":"41.3","Blood RNA - non-classical monocyte [nTPM]":"36.8","Blood RNA - plasmacytoid DC [nTPM]":"7.0","Blood RNA - T-reg [nTPM]":"0.5","Blood RNA - total PBMC [nTPM]":"6.9","Brain RNA - amygdala [nTPM]":"69.4","Brain RNA - basal ganglia [nTPM]":"141.3","Brain RNA - cerebellum [nTPM]":"706.3","Brain RNA - cerebral cortex [nTPM]":"105.2","Brain RNA - hippocampal formation [nTPM]":"40.1","Brain RNA - hypothalamus [nTPM]":"122.6","Brain RNA - medulla oblongata [nTPM]":"301.3","Brain RNA - midbrain [nTPM]":"122.7","Brain RNA - pons [nTPM]":"207.3","Brain RNA - spinal cord [nTPM]":"241.5","Brain RNA - thalamus [nTPM]":"283.3","Brain RNA - white matter [nTPM]":"437.2","Single Cell Type RNA - Adipocytes [nTPM]":"187.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"54.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"138.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"224.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"139.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"113.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"28.6","Single Cell Type RNA - Club cells [nTPM]":"13.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"104.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.6","Single Cell Type RNA - dendritic cells [nTPM]":"94.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"2.6","Single Cell Type RNA - Early spermatids [nTPM]":"20.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"65.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"88.0","Single Cell Type RNA - Endothelial cells [nTPM]":"61.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.5","Single Cell Type RNA - Erythroid cells [nTPM]":"23.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.2","Single Cell Type RNA - Fibroblasts [nTPM]":"30.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"86.6","Single Cell Type RNA - granulocytes [nTPM]":"40.4","Single Cell Type RNA - Granulosa cells [nTPM]":"29.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"37.1","Single Cell Type RNA - Hepatocytes [nTPM]":"43.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"27.7","Single Cell Type RNA - Horizontal cells [nTPM]":"101.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.7","Single Cell Type RNA - Ionocytes [nTPM]":"65.1","Single Cell Type RNA - Kupffer cells [nTPM]":"47.4","Single Cell Type RNA - Langerhans cells [nTPM]":"9.4","Single Cell Type RNA - Late spermatids [nTPM]":"30.7","Single Cell Type RNA - Leydig cells [nTPM]":"11.1","Single Cell Type RNA - Macrophages [nTPM]":"46.7","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"95.5","Single Cell Type RNA - monocytes [nTPM]":"21.8","Single Cell Type RNA - Muller glia cells [nTPM]":"221.7","Single Cell Type RNA - NK-cells [nTPM]":"47.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"9.8","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"138.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"196.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"28.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"51.9","Single Cell Type RNA - Spermatocytes [nTPM]":"4.8","Single Cell Type RNA - Spermatogonia [nTPM]":"2.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.1","Single Cell Type RNA - T-cells [nTPM]":"48.2","Single Cell Type RNA - Theca cells [nTPM]":"8.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.9","Single Cell Type RNA - Urothelial cells [nTPM]":"6.5"},{"Gene":"PLCZ1","Gene synonym":["NYD-SP27","PLCzeta"],"Ensembl":"ENSG00000139151","Gene description":"Phospholipase C zeta 1","Uniprot":["Q86YW0"],"Chromosome":"12","Position":"18683169-18738100","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Fertilization","Lipid degradation","Lipid metabolism"],"Molecular function":["Developmental protein","Hydrolase","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"24","RNA tissue specific nTPM":{"testis":"42.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"47","RNA single cell type specific nTPM":{"Early spermatids":"647.0","Late spermatids":"316.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"amygdala":"3.1"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.4","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"1.7","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"42.3","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.8","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.4","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"647.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"316.3","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"10.1","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PLD1","Gene synonym":[],"Ensembl":"ENSG00000075651","Gene description":"Phospholipase D1","Uniprot":["Q13393"],"Chromosome":"3","Position":"171600404-171810950","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"gallbladder":"86.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Oligodendrocytes":"519.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"8.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HUVEC TERT2":"57.5","SK-MEL-30":"31.1","TIME":"50.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004527","HPA042396","HPA066938"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB004527":"AB_677324","HPA042396":"AB_2677977","HPA066938":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.76e-6"},"Tissue RNA - adipose tissue [nTPM]":"7.8","Tissue RNA - adrenal gland [nTPM]":"26.4","Tissue RNA - amygdala [nTPM]":"9.2","Tissue RNA - appendix [nTPM]":"6.6","Tissue RNA - basal ganglia [nTPM]":"24.7","Tissue RNA - bone marrow [nTPM]":"7.8","Tissue RNA - breast [nTPM]":"7.5","Tissue RNA - cerebellum [nTPM]":"18.4","Tissue RNA - cerebral cortex [nTPM]":"13.6","Tissue RNA - cervix [nTPM]":"10.4","Tissue RNA - choroid plexus [nTPM]":"4.5","Tissue RNA - colon [nTPM]":"14.6","Tissue RNA - duodenum [nTPM]":"46.9","Tissue RNA - endometrium 1 [nTPM]":"6.2","Tissue RNA - epididymis [nTPM]":"2.8","Tissue RNA - esophagus [nTPM]":"33.0","Tissue RNA - fallopian tube [nTPM]":"6.4","Tissue RNA - gallbladder [nTPM]":"86.8","Tissue RNA - heart muscle [nTPM]":"24.4","Tissue RNA - hippocampal formation [nTPM]":"10.5","Tissue RNA - hypothalamus [nTPM]":"14.3","Tissue RNA - kidney [nTPM]":"12.0","Tissue RNA - liver [nTPM]":"33.7","Tissue RNA - lung [nTPM]":"4.7","Tissue RNA - lymph node [nTPM]":"9.1","Tissue RNA - medulla oblongata [nTPM]":"24.8","Tissue RNA - midbrain [nTPM]":"22.0","Tissue RNA - ovary [nTPM]":"24.2","Tissue RNA - pancreas [nTPM]":"21.2","Tissue RNA - parathyroid gland [nTPM]":"1.6","Tissue RNA - pituitary gland [nTPM]":"2.3","Tissue RNA - placenta [nTPM]":"10.7","Tissue RNA - pons [nTPM]":"23.5","Tissue RNA - prostate [nTPM]":"3.4","Tissue RNA - rectum [nTPM]":"14.7","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"13.8","Tissue RNA - seminal vesicle [nTPM]":"6.0","Tissue RNA - skeletal muscle [nTPM]":"2.5","Tissue RNA - skin 1 [nTPM]":"29.2","Tissue RNA - small intestine [nTPM]":"43.9","Tissue RNA - smooth muscle [nTPM]":"4.8","Tissue RNA - spinal cord [nTPM]":"14.7","Tissue RNA - spleen [nTPM]":"15.7","Tissue RNA - stomach 1 [nTPM]":"8.2","Tissue RNA - testis [nTPM]":"5.0","Tissue RNA - thalamus [nTPM]":"19.0","Tissue RNA - thymus [nTPM]":"4.1","Tissue RNA - thyroid gland [nTPM]":"3.7","Tissue RNA - tongue [nTPM]":"6.8","Tissue RNA - tonsil [nTPM]":"10.8","Tissue RNA - urinary bladder [nTPM]":"5.1","Tissue RNA - vagina [nTPM]":"12.4","Tissue RNA - white matter [nTPM]":"41.4","Cell RNA - A-431 [nTPM]":"4.5","Cell RNA - A549 [nTPM]":"7.2","Cell RNA - AF22 [nTPM]":"3.7","Cell RNA - AN3-CA [nTPM]":"1.4","Cell RNA - ASC diff [nTPM]":"11.2","Cell RNA - ASC TERT1 [nTPM]":"12.6","Cell RNA - BEWO [nTPM]":"7.7","Cell RNA - BJ [nTPM]":"2.3","Cell RNA - BJ hTERT+ [nTPM]":"9.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.3","Cell RNA - CACO-2 [nTPM]":"1.1","Cell RNA - CAPAN-2 [nTPM]":"6.4","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"17.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.9","Cell RNA - GAMG [nTPM]":"24.0","Cell RNA - HaCaT [nTPM]":"15.2","Cell RNA - HAP1 [nTPM]":"0.6","Cell RNA - HBEC3-KT [nTPM]":"2.0","Cell RNA - HBF TERT88 [nTPM]":"5.7","Cell RNA - HDLM-2 [nTPM]":"3.6","Cell RNA - HEK 293 [nTPM]":"3.2","Cell RNA - HEL [nTPM]":"4.2","Cell RNA - HeLa [nTPM]":"11.5","Cell RNA - Hep G2 [nTPM]":"26.1","Cell RNA - HHSteC [nTPM]":"4.9","Cell RNA - HL-60 [nTPM]":"7.3","Cell RNA - HMC-1 [nTPM]":"18.9","Cell RNA - HSkMC [nTPM]":"4.9","Cell RNA - hTCEpi [nTPM]":"10.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.2","Cell RNA - hTERT-HME1 [nTPM]":"2.0","Cell RNA - hTERT-RPE1 [nTPM]":"10.0","Cell RNA - HUVEC TERT2 [nTPM]":"57.5","Cell RNA - JURKAT [nTPM]":"1.2","Cell RNA - K-562 [nTPM]":"2.8","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.9","Cell RNA - MCF7 [nTPM]":"1.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"6.4","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"11.9","Cell RNA - PC-3 [nTPM]":"5.1","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"1.5","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"8.9","Cell RNA - RT4 [nTPM]":"1.8","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"7.9","Cell RNA - SK-BR-3 [nTPM]":"4.7","Cell RNA - SK-MEL-30 [nTPM]":"31.1","Cell RNA - SuSa [nTPM]":"5.1","Cell RNA - T-47d [nTPM]":"9.0","Cell RNA - THP-1 [nTPM]":"9.7","Cell RNA - TIME [nTPM]":"50.7","Cell RNA - U-138 MG [nTPM]":"1.5","Cell RNA - U-2 OS [nTPM]":"5.7","Cell RNA - U-2197 [nTPM]":"4.0","Cell RNA - U-251 MG [nTPM]":"2.5","Cell RNA - U-266\/70 [nTPM]":"9.6","Cell RNA - U-266\/84 [nTPM]":"8.2","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"6.7","Cell RNA - U-937 [nTPM]":"8.6","Cell RNA - WM-115 [nTPM]":"1.9","Blood RNA - basophil [nTPM]":"8.3","Blood RNA - classical monocyte [nTPM]":"1.8","Blood RNA - eosinophil [nTPM]":"2.3","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"2.6","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"2.2","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"9.2","Brain RNA - basal ganglia [nTPM]":"24.7","Brain RNA - cerebellum [nTPM]":"18.4","Brain RNA - cerebral cortex [nTPM]":"13.6","Brain RNA - hippocampal formation [nTPM]":"10.5","Brain RNA - hypothalamus [nTPM]":"14.3","Brain RNA - medulla oblongata [nTPM]":"24.8","Brain RNA - midbrain [nTPM]":"22.0","Brain RNA - pons [nTPM]":"23.5","Brain RNA - spinal cord [nTPM]":"14.7","Brain RNA - thalamus [nTPM]":"19.0","Brain RNA - white matter [nTPM]":"41.4","Single Cell Type RNA - Adipocytes [nTPM]":"7.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.7","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"0.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"33.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"57.2","Single Cell Type RNA - Club cells [nTPM]":"11.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"37.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.4","Single Cell Type RNA - Early spermatids [nTPM]":"13.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.8","Single Cell Type RNA - Endothelial cells [nTPM]":"7.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"6.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.7","Single Cell Type RNA - Fibroblasts [nTPM]":"15.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"27.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.3","Single Cell Type RNA - granulocytes [nTPM]":"27.9","Single Cell Type RNA - Granulosa cells [nTPM]":"10.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"15.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.6","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"13.2","Single Cell Type RNA - Langerhans cells [nTPM]":"2.4","Single Cell Type RNA - Late spermatids [nTPM]":"9.5","Single Cell Type RNA - Leydig cells [nTPM]":"10.5","Single Cell Type RNA - Macrophages [nTPM]":"10.2","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"98.4","Single Cell Type RNA - monocytes [nTPM]":"5.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"519.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.4","Single Cell Type RNA - Paneth cells [nTPM]":"18.3","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"3.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"38.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"48.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.4","Single Cell Type RNA - Spermatocytes [nTPM]":"6.1","Single Cell Type RNA - Spermatogonia [nTPM]":"5.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"93.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"34.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.3","Single Cell Type RNA - T-cells [nTPM]":"2.3","Single Cell Type RNA - Theca cells [nTPM]":"12.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.8","Single Cell Type RNA - Urothelial cells [nTPM]":"4.7"},{"Gene":"PLD3","Gene synonym":["HU-K4"],"Ensembl":"ENSG00000105223","Gene description":"Phospholipase D family member 3","Uniprot":["Q8IV08"],"Chromosome":"19","Position":"40348456-40380439","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity","Inflammatory response"],"Molecular function":["Exonuclease","Hydrolase","Nuclease"],"Disease involvement":["Disease variant","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pituitary gland":"711.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"688.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"1727.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"1727.4"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012800","CAB020812"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"450000","Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Endoplasmic reticulum","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB020812":null,"HPA012800":"AB_1855330"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.44e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.21e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Tissue RNA - adipose tissue [nTPM]":"169.3","Tissue RNA - adrenal gland [nTPM]":"200.0","Tissue RNA - amygdala [nTPM]":"143.3","Tissue RNA - appendix [nTPM]":"78.4","Tissue RNA - basal ganglia [nTPM]":"159.7","Tissue RNA - bone marrow [nTPM]":"48.3","Tissue RNA - breast [nTPM]":"138.4","Tissue RNA - cerebellum [nTPM]":"46.0","Tissue RNA - cerebral cortex [nTPM]":"229.7","Tissue RNA - cervix [nTPM]":"139.4","Tissue RNA - choroid plexus [nTPM]":"54.0","Tissue RNA - colon [nTPM]":"131.4","Tissue RNA - duodenum [nTPM]":"71.7","Tissue RNA - endometrium 1 [nTPM]":"155.7","Tissue RNA - epididymis [nTPM]":"84.7","Tissue RNA - esophagus [nTPM]":"84.9","Tissue RNA - fallopian tube [nTPM]":"133.5","Tissue RNA - gallbladder [nTPM]":"96.7","Tissue RNA - heart muscle [nTPM]":"206.1","Tissue RNA - hippocampal formation [nTPM]":"202.5","Tissue RNA - hypothalamus [nTPM]":"294.4","Tissue RNA - kidney [nTPM]":"130.2","Tissue RNA - liver [nTPM]":"121.3","Tissue RNA - lung [nTPM]":"181.5","Tissue RNA - lymph node [nTPM]":"98.1","Tissue RNA - medulla oblongata [nTPM]":"132.4","Tissue RNA - midbrain [nTPM]":"128.5","Tissue RNA - ovary [nTPM]":"199.0","Tissue RNA - pancreas [nTPM]":"151.0","Tissue RNA - parathyroid gland [nTPM]":"105.9","Tissue RNA - pituitary gland [nTPM]":"711.9","Tissue RNA - placenta [nTPM]":"123.4","Tissue RNA - pons [nTPM]":"137.9","Tissue RNA - prostate [nTPM]":"133.4","Tissue RNA - rectum [nTPM]":"49.2","Tissue RNA - retina [nTPM]":"51.4","Tissue RNA - salivary gland [nTPM]":"138.7","Tissue RNA - seminal vesicle [nTPM]":"106.2","Tissue RNA - skeletal muscle [nTPM]":"105.1","Tissue RNA - skin 1 [nTPM]":"120.5","Tissue RNA - small intestine [nTPM]":"105.3","Tissue RNA - smooth muscle [nTPM]":"79.1","Tissue RNA - spinal cord [nTPM]":"63.8","Tissue RNA - spleen [nTPM]":"197.0","Tissue RNA - stomach 1 [nTPM]":"126.5","Tissue RNA - testis [nTPM]":"77.7","Tissue RNA - thalamus [nTPM]":"197.7","Tissue RNA - thymus [nTPM]":"44.3","Tissue RNA - thyroid gland [nTPM]":"120.8","Tissue RNA - tongue [nTPM]":"82.3","Tissue RNA - tonsil [nTPM]":"41.4","Tissue RNA - urinary bladder [nTPM]":"126.2","Tissue RNA - vagina [nTPM]":"126.0","Tissue RNA - white matter [nTPM]":"129.6","Cell RNA - A-431 [nTPM]":"85.6","Cell RNA - A549 [nTPM]":"257.8","Cell RNA - AF22 [nTPM]":"163.7","Cell RNA - AN3-CA [nTPM]":"259.1","Cell RNA - ASC diff [nTPM]":"444.2","Cell RNA - ASC TERT1 [nTPM]":"210.2","Cell RNA - BEWO [nTPM]":"124.5","Cell RNA - BJ [nTPM]":"206.5","Cell RNA - BJ hTERT+ [nTPM]":"208.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"146.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"166.6","Cell RNA - CACO-2 [nTPM]":"49.4","Cell RNA - CAPAN-2 [nTPM]":"93.8","Cell RNA - Daudi [nTPM]":"36.9","Cell RNA - EFO-21 [nTPM]":"211.0","Cell RNA - fHDF\/TERT166 [nTPM]":"180.9","Cell RNA - GAMG [nTPM]":"47.8","Cell RNA - HaCaT [nTPM]":"39.3","Cell RNA - HAP1 [nTPM]":"39.9","Cell RNA - HBEC3-KT [nTPM]":"81.2","Cell RNA - HBF TERT88 [nTPM]":"63.5","Cell RNA - HDLM-2 [nTPM]":"138.4","Cell RNA - HEK 293 [nTPM]":"145.3","Cell RNA - HEL [nTPM]":"39.9","Cell RNA - HeLa [nTPM]":"82.1","Cell RNA - Hep G2 [nTPM]":"63.2","Cell RNA - HHSteC [nTPM]":"302.7","Cell RNA - HL-60 [nTPM]":"16.8","Cell RNA - HMC-1 [nTPM]":"435.1","Cell RNA - HSkMC [nTPM]":"402.5","Cell RNA - hTCEpi [nTPM]":"167.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"112.1","Cell RNA - hTERT-HME1 [nTPM]":"76.6","Cell RNA - hTERT-RPE1 [nTPM]":"244.2","Cell RNA - HUVEC TERT2 [nTPM]":"125.0","Cell RNA - JURKAT [nTPM]":"59.3","Cell RNA - K-562 [nTPM]":"142.5","Cell RNA - Karpas-707 [nTPM]":"144.5","Cell RNA - LHCN-M2 [nTPM]":"106.7","Cell RNA - MCF7 [nTPM]":"111.5","Cell RNA - MOLT-4 [nTPM]":"29.5","Cell RNA - NB-4 [nTPM]":"79.6","Cell RNA - NTERA-2 [nTPM]":"107.4","Cell RNA - OE19 [nTPM]":"138.7","Cell RNA - PC-3 [nTPM]":"52.8","Cell RNA - REH [nTPM]":"37.0","Cell RNA - RH-30 [nTPM]":"124.5","Cell RNA - RPMI-8226 [nTPM]":"154.2","Cell RNA - RPTEC TERT1 [nTPM]":"75.2","Cell RNA - RT4 [nTPM]":"63.2","Cell RNA - SCLC-21H [nTPM]":"116.7","Cell RNA - SH-SY5Y [nTPM]":"193.9","Cell RNA - SiHa [nTPM]":"99.0","Cell RNA - SK-BR-3 [nTPM]":"60.6","Cell RNA - SK-MEL-30 [nTPM]":"113.8","Cell RNA - SuSa [nTPM]":"169.5","Cell RNA - T-47d [nTPM]":"83.6","Cell RNA - THP-1 [nTPM]":"283.2","Cell RNA - TIME [nTPM]":"222.3","Cell RNA - U-138 MG [nTPM]":"122.8","Cell RNA - U-2 OS [nTPM]":"58.5","Cell RNA - U-2197 [nTPM]":"105.6","Cell RNA - U-251 MG [nTPM]":"47.0","Cell RNA - U-266\/70 [nTPM]":"148.9","Cell RNA - U-266\/84 [nTPM]":"173.3","Cell RNA - U-698 [nTPM]":"38.8","Cell RNA - U-87 MG [nTPM]":"197.7","Cell RNA - U-937 [nTPM]":"66.2","Cell RNA - WM-115 [nTPM]":"77.9","Blood RNA - basophil [nTPM]":"1727.4","Blood RNA - classical monocyte [nTPM]":"256.7","Blood RNA - eosinophil [nTPM]":"378.7","Blood RNA - gdT-cell [nTPM]":"75.0","Blood RNA - intermediate monocyte [nTPM]":"129.5","Blood RNA - MAIT T-cell [nTPM]":"62.0","Blood RNA - memory B-cell [nTPM]":"34.4","Blood RNA - memory CD4 T-cell [nTPM]":"59.5","Blood RNA - memory CD8 T-cell [nTPM]":"67.7","Blood RNA - myeloid DC [nTPM]":"235.0","Blood RNA - naive B-cell [nTPM]":"28.1","Blood RNA - naive CD4 T-cell [nTPM]":"60.8","Blood RNA - naive CD8 T-cell [nTPM]":"61.3","Blood RNA - neutrophil [nTPM]":"25.7","Blood RNA - NK-cell [nTPM]":"102.3","Blood RNA - non-classical monocyte [nTPM]":"64.2","Blood RNA - plasmacytoid DC [nTPM]":"34.7","Blood RNA - T-reg [nTPM]":"64.5","Blood RNA - total PBMC [nTPM]":"208.6","Brain RNA - amygdala [nTPM]":"143.3","Brain RNA - basal ganglia [nTPM]":"159.7","Brain RNA - cerebellum [nTPM]":"46.0","Brain RNA - cerebral cortex [nTPM]":"229.7","Brain RNA - hippocampal formation [nTPM]":"202.5","Brain RNA - hypothalamus [nTPM]":"294.4","Brain RNA - medulla oblongata [nTPM]":"132.4","Brain RNA - midbrain [nTPM]":"128.5","Brain RNA - pons [nTPM]":"137.9","Brain RNA - spinal cord [nTPM]":"63.8","Brain RNA - thalamus [nTPM]":"197.7","Brain RNA - white matter [nTPM]":"129.6","Single Cell Type RNA - Adipocytes [nTPM]":"66.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"69.6","Single Cell Type RNA - Astrocytes [nTPM]":"59.4","Single Cell Type RNA - B-cells [nTPM]":"27.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"35.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"93.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"263.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"39.9","Single Cell Type RNA - Bipolar cells [nTPM]":"101.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"45.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"61.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"22.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"45.8","Single Cell Type RNA - Club cells [nTPM]":"90.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"57.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"158.2","Single Cell Type RNA - dendritic cells [nTPM]":"27.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"42.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"52.5","Single Cell Type RNA - Early spermatids [nTPM]":"8.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"32.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"49.8","Single Cell Type RNA - Endothelial cells [nTPM]":"53.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"72.8","Single Cell Type RNA - Erythroid cells [nTPM]":"18.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"99.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"58.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"107.2","Single Cell Type RNA - Fibroblasts [nTPM]":"158.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"38.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"31.5","Single Cell Type RNA - granulocytes [nTPM]":"60.3","Single Cell Type RNA - Granulosa cells [nTPM]":"134.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"88.2","Single Cell Type RNA - Hepatocytes [nTPM]":"43.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"688.4","Single Cell Type RNA - Horizontal cells [nTPM]":"121.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"113.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"41.3","Single Cell Type RNA - Ionocytes [nTPM]":"126.1","Single Cell Type RNA - Kupffer cells [nTPM]":"280.9","Single Cell Type RNA - Langerhans cells [nTPM]":"59.1","Single Cell Type RNA - Late spermatids [nTPM]":"15.7","Single Cell Type RNA - Leydig cells [nTPM]":"151.6","Single Cell Type RNA - Macrophages [nTPM]":"261.3","Single Cell Type RNA - Melanocytes [nTPM]":"92.5","Single Cell Type RNA - Microglial cells [nTPM]":"50.6","Single Cell Type RNA - monocytes [nTPM]":"54.2","Single Cell Type RNA - Muller glia cells [nTPM]":"94.1","Single Cell Type RNA - NK-cells [nTPM]":"35.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"53.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"70.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"54.3","Single Cell Type RNA - Paneth cells [nTPM]":"42.6","Single Cell Type RNA - Peritubular cells [nTPM]":"143.7","Single Cell Type RNA - Plasma cells [nTPM]":"85.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"57.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"78.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"37.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"35.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"47.6","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"73.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"59.7","Single Cell Type RNA - Spermatocytes [nTPM]":"24.2","Single Cell Type RNA - Spermatogonia [nTPM]":"67.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"32.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"33.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"195.9","Single Cell Type RNA - T-cells [nTPM]":"28.8","Single Cell Type RNA - Theca cells [nTPM]":"114.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"41.6","Single Cell Type RNA - Urothelial cells [nTPM]":"68.2"},{"Gene":"PLK1","Gene synonym":["PLK"],"Ensembl":"ENSG00000166851","Gene description":"Polo like kinase 1","Uniprot":["P53350"],"Chromosome":"16","Position":"23677656-23690367","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Mitosis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"32.0","lymphoid tissue":"43.9","testis":"33.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"32.3","Early spermatids":"123.7","Erythroid cells":"38.3","Extravillous trophoblasts":"55.9","Spermatocytes":"79.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"T-reg":"5.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"T-cells":"5.6"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051638","HPA053229"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051638":"AB_2681561","HPA053229":"AB_2682084"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.21e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.70e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.28e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.12e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.4","Tissue RNA - adrenal gland [nTPM]":"1.5","Tissue RNA - amygdala [nTPM]":"2.3","Tissue RNA - appendix [nTPM]":"13.4","Tissue RNA - basal ganglia [nTPM]":"2.3","Tissue RNA - bone marrow [nTPM]":"32.0","Tissue RNA - breast [nTPM]":"1.5","Tissue RNA - cerebellum [nTPM]":"2.5","Tissue RNA - cerebral cortex [nTPM]":"3.2","Tissue RNA - cervix [nTPM]":"2.3","Tissue RNA - choroid plexus [nTPM]":"2.0","Tissue RNA - colon [nTPM]":"9.6","Tissue RNA - duodenum [nTPM]":"10.4","Tissue RNA - endometrium 1 [nTPM]":"1.2","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"13.9","Tissue RNA - fallopian tube [nTPM]":"1.0","Tissue RNA - gallbladder [nTPM]":"1.4","Tissue RNA - heart muscle [nTPM]":"1.0","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"2.1","Tissue RNA - kidney [nTPM]":"1.4","Tissue RNA - liver [nTPM]":"1.9","Tissue RNA - lung [nTPM]":"1.9","Tissue RNA - lymph node [nTPM]":"27.8","Tissue RNA - medulla oblongata [nTPM]":"2.3","Tissue RNA - midbrain [nTPM]":"2.3","Tissue RNA - ovary [nTPM]":"1.3","Tissue RNA - pancreas [nTPM]":"1.1","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"1.2","Tissue RNA - placenta [nTPM]":"6.4","Tissue RNA - pons [nTPM]":"2.2","Tissue RNA - prostate [nTPM]":"1.2","Tissue RNA - rectum [nTPM]":"10.1","Tissue RNA - retina [nTPM]":"1.2","Tissue RNA - salivary gland [nTPM]":"2.4","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"1.0","Tissue RNA - skin 1 [nTPM]":"5.7","Tissue RNA - small intestine [nTPM]":"9.2","Tissue RNA - smooth muscle [nTPM]":"4.0","Tissue RNA - spinal cord [nTPM]":"2.0","Tissue RNA - spleen [nTPM]":"9.1","Tissue RNA - stomach 1 [nTPM]":"6.2","Tissue RNA - testis [nTPM]":"33.1","Tissue RNA - thalamus [nTPM]":"2.5","Tissue RNA - thymus [nTPM]":"43.9","Tissue RNA - thyroid gland [nTPM]":"0.9","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"30.0","Tissue RNA - urinary bladder [nTPM]":"2.8","Tissue RNA - vagina [nTPM]":"4.0","Tissue RNA - white matter [nTPM]":"2.8","Cell RNA - A-431 [nTPM]":"199.9","Cell RNA - A549 [nTPM]":"207.5","Cell RNA - AF22 [nTPM]":"166.2","Cell RNA - AN3-CA [nTPM]":"90.9","Cell RNA - ASC diff [nTPM]":"5.2","Cell RNA - ASC TERT1 [nTPM]":"11.7","Cell RNA - BEWO [nTPM]":"92.8","Cell RNA - BJ [nTPM]":"111.0","Cell RNA - BJ hTERT+ [nTPM]":"74.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"172.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"127.0","Cell RNA - CACO-2 [nTPM]":"184.3","Cell RNA - CAPAN-2 [nTPM]":"131.0","Cell RNA - Daudi [nTPM]":"99.1","Cell RNA - EFO-21 [nTPM]":"56.3","Cell RNA - fHDF\/TERT166 [nTPM]":"76.5","Cell RNA - GAMG [nTPM]":"90.1","Cell RNA - HaCaT [nTPM]":"112.8","Cell RNA - HAP1 [nTPM]":"229.5","Cell RNA - HBEC3-KT [nTPM]":"93.5","Cell RNA - HBF TERT88 [nTPM]":"206.1","Cell RNA - HDLM-2 [nTPM]":"139.5","Cell RNA - HEK 293 [nTPM]":"128.0","Cell RNA - HEL [nTPM]":"125.2","Cell RNA - HeLa [nTPM]":"163.4","Cell RNA - Hep G2 [nTPM]":"257.1","Cell RNA - HHSteC [nTPM]":"1.7","Cell RNA - HL-60 [nTPM]":"147.5","Cell RNA - HMC-1 [nTPM]":"133.7","Cell RNA - HSkMC [nTPM]":"4.8","Cell RNA - hTCEpi [nTPM]":"5.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"124.7","Cell RNA - hTERT-HME1 [nTPM]":"125.2","Cell RNA - hTERT-RPE1 [nTPM]":"21.6","Cell RNA - HUVEC TERT2 [nTPM]":"127.9","Cell RNA - JURKAT [nTPM]":"127.5","Cell RNA - K-562 [nTPM]":"200.7","Cell RNA - Karpas-707 [nTPM]":"133.9","Cell RNA - LHCN-M2 [nTPM]":"134.8","Cell RNA - MCF7 [nTPM]":"187.8","Cell RNA - MOLT-4 [nTPM]":"139.8","Cell RNA - NB-4 [nTPM]":"151.4","Cell RNA - NTERA-2 [nTPM]":"189.5","Cell RNA - OE19 [nTPM]":"82.1","Cell RNA - PC-3 [nTPM]":"103.5","Cell RNA - REH [nTPM]":"217.2","Cell RNA - RH-30 [nTPM]":"111.7","Cell RNA - RPMI-8226 [nTPM]":"160.0","Cell RNA - RPTEC TERT1 [nTPM]":"49.3","Cell RNA - RT4 [nTPM]":"43.9","Cell RNA - SCLC-21H [nTPM]":"94.3","Cell RNA - SH-SY5Y [nTPM]":"65.3","Cell RNA - SiHa [nTPM]":"126.8","Cell RNA - SK-BR-3 [nTPM]":"88.9","Cell RNA - SK-MEL-30 [nTPM]":"55.8","Cell RNA - SuSa [nTPM]":"94.4","Cell RNA - T-47d [nTPM]":"114.4","Cell RNA - THP-1 [nTPM]":"92.1","Cell RNA - TIME [nTPM]":"65.1","Cell RNA - U-138 MG [nTPM]":"82.7","Cell RNA - U-2 OS [nTPM]":"102.7","Cell RNA - U-2197 [nTPM]":"79.9","Cell RNA - U-251 MG [nTPM]":"194.1","Cell RNA - U-266\/70 [nTPM]":"93.2","Cell RNA - U-266\/84 [nTPM]":"156.8","Cell RNA - U-698 [nTPM]":"173.6","Cell RNA - U-87 MG [nTPM]":"69.3","Cell RNA - U-937 [nTPM]":"127.7","Cell RNA - WM-115 [nTPM]":"137.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"1.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.9","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"5.6","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"2.3","Brain RNA - basal ganglia [nTPM]":"2.3","Brain RNA - cerebellum [nTPM]":"2.5","Brain RNA - cerebral cortex [nTPM]":"3.2","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"2.1","Brain RNA - medulla oblongata [nTPM]":"2.3","Brain RNA - midbrain [nTPM]":"2.3","Brain RNA - pons [nTPM]":"2.2","Brain RNA - spinal cord [nTPM]":"2.0","Brain RNA - thalamus [nTPM]":"2.5","Brain RNA - white matter [nTPM]":"2.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"7.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"32.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"123.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.3","Single Cell Type RNA - Endothelial cells [nTPM]":"2.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"38.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"55.9","Single Cell Type RNA - Fibroblasts [nTPM]":"4.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.8","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"19.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"1.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.3","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"6.9","Single Cell Type RNA - Langerhans cells [nTPM]":"3.2","Single Cell Type RNA - Late spermatids [nTPM]":"13.9","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"7.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.4","Single Cell Type RNA - Muller glia cells [nTPM]":"1.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"23.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.1","Single Cell Type RNA - Spermatocytes [nTPM]":"79.5","Single Cell Type RNA - Spermatogonia [nTPM]":"13.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.8","Single Cell Type RNA - T-cells [nTPM]":"2.5","Single Cell Type RNA - Theca cells [nTPM]":"1.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.9","Single Cell Type RNA - Urothelial cells [nTPM]":"2.0"},{"Gene":"PLK4","Gene synonym":["Sak","STK18"],"Ensembl":"ENSG00000142731","Gene description":"Polo like kinase 4","Uniprot":["O00444"],"Chromosome":"4","Position":"127880893-127899224","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"bone marrow":"22.6","lymphoid tissue":"14.4","testis":"22.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"65.9","Late spermatids":"87.5","Spermatocytes":"53.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017327","HPA035026","HPA043198"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Centrosome","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA017327":"AB_2669584","HPA035026":"AB_10602080","HPA043198":"AB_2732504"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.46e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.13e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.14e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.0","Tissue RNA - adrenal gland [nTPM]":"1.1","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"4.9","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"22.6","Tissue RNA - breast [nTPM]":"2.0","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.7","Tissue RNA - cervix [nTPM]":"0.9","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"3.5","Tissue RNA - duodenum [nTPM]":"2.8","Tissue RNA - endometrium 1 [nTPM]":"1.5","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"3.2","Tissue RNA - fallopian tube [nTPM]":"1.3","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"0.8","Tissue RNA - lung [nTPM]":"0.9","Tissue RNA - lymph node [nTPM]":"7.4","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.5","Tissue RNA - ovary [nTPM]":"1.0","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"0.6","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"3.6","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"0.9","Tissue RNA - rectum [nTPM]":"4.3","Tissue RNA - retina [nTPM]":"2.1","Tissue RNA - salivary gland [nTPM]":"0.9","Tissue RNA - seminal vesicle [nTPM]":"0.9","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"2.3","Tissue RNA - small intestine [nTPM]":"2.9","Tissue RNA - smooth muscle [nTPM]":"1.8","Tissue RNA - spinal cord [nTPM]":"0.4","Tissue RNA - spleen [nTPM]":"1.6","Tissue RNA - stomach 1 [nTPM]":"2.0","Tissue RNA - testis [nTPM]":"22.6","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"14.4","Tissue RNA - thyroid gland [nTPM]":"0.9","Tissue RNA - tongue [nTPM]":"0.7","Tissue RNA - tonsil [nTPM]":"7.3","Tissue RNA - urinary bladder [nTPM]":"1.3","Tissue RNA - vagina [nTPM]":"1.4","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"26.1","Cell RNA - A549 [nTPM]":"12.1","Cell RNA - AF22 [nTPM]":"44.3","Cell RNA - AN3-CA [nTPM]":"22.9","Cell RNA - ASC diff [nTPM]":"1.5","Cell RNA - ASC TERT1 [nTPM]":"4.2","Cell RNA - BEWO [nTPM]":"20.1","Cell RNA - BJ [nTPM]":"24.9","Cell RNA - BJ hTERT+ [nTPM]":"17.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"32.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"33.3","Cell RNA - CACO-2 [nTPM]":"17.0","Cell RNA - CAPAN-2 [nTPM]":"26.1","Cell RNA - Daudi [nTPM]":"34.9","Cell RNA - EFO-21 [nTPM]":"9.0","Cell RNA - fHDF\/TERT166 [nTPM]":"13.9","Cell RNA - GAMG [nTPM]":"26.3","Cell RNA - HaCaT [nTPM]":"16.7","Cell RNA - HAP1 [nTPM]":"31.6","Cell RNA - HBEC3-KT [nTPM]":"19.9","Cell RNA - HBF TERT88 [nTPM]":"49.6","Cell RNA - HDLM-2 [nTPM]":"27.4","Cell RNA - HEK 293 [nTPM]":"13.1","Cell RNA - HEL [nTPM]":"31.6","Cell RNA - HeLa [nTPM]":"20.0","Cell RNA - Hep G2 [nTPM]":"16.0","Cell RNA - HHSteC [nTPM]":"0.5","Cell RNA - HL-60 [nTPM]":"45.2","Cell RNA - HMC-1 [nTPM]":"35.9","Cell RNA - HSkMC [nTPM]":"1.4","Cell RNA - hTCEpi [nTPM]":"2.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"29.7","Cell RNA - hTERT-HME1 [nTPM]":"13.6","Cell RNA - hTERT-RPE1 [nTPM]":"5.9","Cell RNA - HUVEC TERT2 [nTPM]":"25.3","Cell RNA - JURKAT [nTPM]":"26.3","Cell RNA - K-562 [nTPM]":"37.5","Cell RNA - Karpas-707 [nTPM]":"45.2","Cell RNA - LHCN-M2 [nTPM]":"27.6","Cell RNA - MCF7 [nTPM]":"18.2","Cell RNA - MOLT-4 [nTPM]":"69.9","Cell RNA - NB-4 [nTPM]":"20.1","Cell RNA - NTERA-2 [nTPM]":"20.7","Cell RNA - OE19 [nTPM]":"26.3","Cell RNA - PC-3 [nTPM]":"13.6","Cell RNA - REH [nTPM]":"36.0","Cell RNA - RH-30 [nTPM]":"30.9","Cell RNA - RPMI-8226 [nTPM]":"12.1","Cell RNA - RPTEC TERT1 [nTPM]":"10.8","Cell RNA - RT4 [nTPM]":"16.4","Cell RNA - SCLC-21H [nTPM]":"24.4","Cell RNA - SH-SY5Y [nTPM]":"20.0","Cell RNA - SiHa [nTPM]":"15.8","Cell RNA - SK-BR-3 [nTPM]":"14.2","Cell RNA - SK-MEL-30 [nTPM]":"7.6","Cell RNA - SuSa [nTPM]":"18.7","Cell RNA - T-47d [nTPM]":"11.5","Cell RNA - THP-1 [nTPM]":"19.3","Cell RNA - TIME [nTPM]":"11.0","Cell RNA - U-138 MG [nTPM]":"25.3","Cell RNA - U-2 OS [nTPM]":"24.4","Cell RNA - U-2197 [nTPM]":"17.4","Cell RNA - U-251 MG [nTPM]":"31.4","Cell RNA - U-266\/70 [nTPM]":"23.1","Cell RNA - U-266\/84 [nTPM]":"27.4","Cell RNA - U-698 [nTPM]":"49.0","Cell RNA - U-87 MG [nTPM]":"13.0","Cell RNA - U-937 [nTPM]":"33.7","Cell RNA - WM-115 [nTPM]":"28.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.7","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.5","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.4","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"1.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"1.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.6","Single Cell Type RNA - Early spermatids [nTPM]":"65.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"19.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.9","Single Cell Type RNA - Fibroblasts [nTPM]":"1.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"7.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.3","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.6","Single Cell Type RNA - Late spermatids [nTPM]":"87.5","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"1.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"1.2","Single Cell Type RNA - Muller glia cells [nTPM]":"1.1","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"8.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.6","Single Cell Type RNA - Spermatocytes [nTPM]":"53.5","Single Cell Type RNA - Spermatogonia [nTPM]":"13.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.8","Single Cell Type RNA - T-cells [nTPM]":"2.1","Single Cell Type RNA - Theca cells [nTPM]":"0.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.5","Single Cell Type RNA - Urothelial cells [nTPM]":"1.7"},{"Gene":"PLN","Gene synonym":["CMD1P","PLB"],"Ensembl":"ENSG00000198523","Gene description":"Phospholamban","Uniprot":["P26678"],"Chromosome":"6","Position":"118548296-118561716","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cardiomyopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"heart muscle":"1563.4","skeletal muscle":"507.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Cardiomyocytes":"2452.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005597","HPA026900"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB005597":"AB_2252716","HPA026900":"AB_1855314"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.11e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.59e-4"},"Tissue RNA - adipose tissue [nTPM]":"40.1","Tissue RNA - adrenal gland [nTPM]":"12.3","Tissue RNA - amygdala [nTPM]":"1.5","Tissue RNA - appendix [nTPM]":"12.3","Tissue RNA - basal ganglia [nTPM]":"3.0","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"15.9","Tissue RNA - cerebellum [nTPM]":"2.9","Tissue RNA - cerebral cortex [nTPM]":"4.0","Tissue RNA - cervix [nTPM]":"31.7","Tissue RNA - choroid plexus [nTPM]":"2.0","Tissue RNA - colon [nTPM]":"148.7","Tissue RNA - duodenum [nTPM]":"13.6","Tissue RNA - endometrium 1 [nTPM]":"121.7","Tissue RNA - epididymis [nTPM]":"21.8","Tissue RNA - esophagus [nTPM]":"43.9","Tissue RNA - fallopian tube [nTPM]":"81.9","Tissue RNA - gallbladder [nTPM]":"92.2","Tissue RNA - heart muscle [nTPM]":"1563.4","Tissue RNA - hippocampal formation [nTPM]":"1.6","Tissue RNA - hypothalamus [nTPM]":"1.6","Tissue RNA - kidney [nTPM]":"15.0","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"15.4","Tissue RNA - lymph node [nTPM]":"2.7","Tissue RNA - medulla oblongata [nTPM]":"1.8","Tissue RNA - midbrain [nTPM]":"2.0","Tissue RNA - ovary [nTPM]":"20.4","Tissue RNA - pancreas [nTPM]":"3.2","Tissue RNA - parathyroid gland [nTPM]":"1.3","Tissue RNA - pituitary gland [nTPM]":"1.5","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"1.8","Tissue RNA - prostate [nTPM]":"35.1","Tissue RNA - rectum [nTPM]":"24.4","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"5.3","Tissue RNA - seminal vesicle [nTPM]":"37.0","Tissue RNA - skeletal muscle [nTPM]":"507.3","Tissue RNA - skin 1 [nTPM]":"8.3","Tissue RNA - small intestine [nTPM]":"41.6","Tissue RNA - smooth muscle [nTPM]":"128.4","Tissue RNA - spinal cord [nTPM]":"1.5","Tissue RNA - spleen [nTPM]":"3.0","Tissue RNA - stomach 1 [nTPM]":"34.1","Tissue RNA - testis [nTPM]":"4.3","Tissue RNA - thalamus [nTPM]":"2.2","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"12.7","Tissue RNA - tongue [nTPM]":"230.2","Tissue RNA - tonsil [nTPM]":"0.9","Tissue RNA - urinary bladder [nTPM]":"44.1","Tissue RNA - vagina [nTPM]":"22.9","Tissue RNA - white matter [nTPM]":"2.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.5","Brain RNA - basal ganglia [nTPM]":"3.0","Brain RNA - cerebellum [nTPM]":"2.9","Brain RNA - cerebral cortex [nTPM]":"4.0","Brain RNA - hippocampal formation [nTPM]":"1.6","Brain RNA - hypothalamus [nTPM]":"1.6","Brain RNA - medulla oblongata [nTPM]":"1.8","Brain RNA - midbrain [nTPM]":"2.0","Brain RNA - pons [nTPM]":"1.8","Brain RNA - spinal cord [nTPM]":"1.5","Brain RNA - thalamus [nTPM]":"2.2","Brain RNA - white matter [nTPM]":"2.0","Single Cell Type RNA - Adipocytes [nTPM]":"4.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"1.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2452.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"108.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"21.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"49.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"4.7","Single Cell Type RNA - Late spermatids [nTPM]":"25.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"11.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"276.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"248.0","Single Cell Type RNA - Spermatocytes [nTPM]":"9.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"PLOD1","Gene synonym":["LH1","LLH","PLOD"],"Ensembl":"ENSG00000083444","Gene description":"Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1","Uniprot":["Q02809"],"Chromosome":"1","Position":"11934205-11975538","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Dioxygenase","Oxidoreductase"],"Disease involvement":["Disease variant","Ehlers-Danlos syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"236.8","Sertoli cells":"105.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049137","HPA055799"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3600000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA049137":"AB_2680649","HPA055799":"AB_2682924"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.79e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.91e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.43e-4"},"Tissue RNA - adipose tissue [nTPM]":"58.1","Tissue RNA - adrenal gland [nTPM]":"34.6","Tissue RNA - amygdala [nTPM]":"46.3","Tissue RNA - appendix [nTPM]":"35.2","Tissue RNA - basal ganglia [nTPM]":"51.2","Tissue RNA - bone marrow [nTPM]":"16.1","Tissue RNA - breast [nTPM]":"41.2","Tissue RNA - cerebellum [nTPM]":"48.6","Tissue RNA - cerebral cortex [nTPM]":"56.6","Tissue RNA - cervix [nTPM]":"65.4","Tissue RNA - choroid plexus [nTPM]":"46.4","Tissue RNA - colon [nTPM]":"47.3","Tissue RNA - duodenum [nTPM]":"37.7","Tissue RNA - endometrium 1 [nTPM]":"65.0","Tissue RNA - epididymis [nTPM]":"30.5","Tissue RNA - esophagus [nTPM]":"21.3","Tissue RNA - fallopian tube [nTPM]":"51.1","Tissue RNA - gallbladder [nTPM]":"42.0","Tissue RNA - heart muscle [nTPM]":"71.2","Tissue RNA - hippocampal formation [nTPM]":"44.5","Tissue RNA - hypothalamus [nTPM]":"47.4","Tissue RNA - kidney [nTPM]":"45.5","Tissue RNA - liver [nTPM]":"78.1","Tissue RNA - lung [nTPM]":"44.4","Tissue RNA - lymph node [nTPM]":"15.4","Tissue RNA - medulla oblongata [nTPM]":"49.6","Tissue RNA - midbrain [nTPM]":"50.8","Tissue RNA - ovary [nTPM]":"54.4","Tissue RNA - pancreas [nTPM]":"39.0","Tissue RNA - parathyroid gland [nTPM]":"36.9","Tissue RNA - pituitary gland [nTPM]":"29.6","Tissue RNA - placenta [nTPM]":"83.8","Tissue RNA - pons [nTPM]":"52.4","Tissue RNA - prostate [nTPM]":"34.7","Tissue RNA - rectum [nTPM]":"23.2","Tissue RNA - retina [nTPM]":"10.6","Tissue RNA - salivary gland [nTPM]":"75.9","Tissue RNA - seminal vesicle [nTPM]":"40.6","Tissue RNA - skeletal muscle [nTPM]":"40.5","Tissue RNA - skin 1 [nTPM]":"27.2","Tissue RNA - small intestine [nTPM]":"35.6","Tissue RNA - smooth muscle [nTPM]":"78.4","Tissue RNA - spinal cord [nTPM]":"44.8","Tissue RNA - spleen [nTPM]":"31.5","Tissue RNA - stomach 1 [nTPM]":"35.5","Tissue RNA - testis [nTPM]":"11.6","Tissue RNA - thalamus [nTPM]":"52.2","Tissue RNA - thymus [nTPM]":"7.9","Tissue RNA - thyroid gland [nTPM]":"34.9","Tissue RNA - tongue [nTPM]":"41.6","Tissue RNA - tonsil [nTPM]":"12.9","Tissue RNA - urinary bladder [nTPM]":"42.4","Tissue RNA - vagina [nTPM]":"36.0","Tissue RNA - white matter [nTPM]":"53.1","Cell RNA - A-431 [nTPM]":"112.5","Cell RNA - A549 [nTPM]":"91.4","Cell RNA - AF22 [nTPM]":"51.3","Cell RNA - AN3-CA [nTPM]":"239.7","Cell RNA - ASC diff [nTPM]":"343.4","Cell RNA - ASC TERT1 [nTPM]":"190.6","Cell RNA - BEWO [nTPM]":"39.0","Cell RNA - BJ [nTPM]":"330.4","Cell RNA - BJ hTERT+ [nTPM]":"436.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"170.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"287.1","Cell RNA - CACO-2 [nTPM]":"105.2","Cell RNA - CAPAN-2 [nTPM]":"71.5","Cell RNA - Daudi [nTPM]":"63.1","Cell RNA - EFO-21 [nTPM]":"339.5","Cell RNA - fHDF\/TERT166 [nTPM]":"367.3","Cell RNA - GAMG [nTPM]":"125.9","Cell RNA - HaCaT [nTPM]":"93.4","Cell RNA - HAP1 [nTPM]":"75.6","Cell RNA - HBEC3-KT [nTPM]":"115.6","Cell RNA - HBF TERT88 [nTPM]":"115.6","Cell RNA - HDLM-2 [nTPM]":"66.2","Cell RNA - HEK 293 [nTPM]":"78.3","Cell RNA - HEL [nTPM]":"34.0","Cell RNA - HeLa [nTPM]":"136.6","Cell RNA - Hep G2 [nTPM]":"137.3","Cell RNA - HHSteC [nTPM]":"212.5","Cell RNA - HL-60 [nTPM]":"21.9","Cell RNA - HMC-1 [nTPM]":"162.7","Cell RNA - HSkMC [nTPM]":"234.0","Cell RNA - hTCEpi [nTPM]":"59.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"206.2","Cell RNA - hTERT-HME1 [nTPM]":"81.9","Cell RNA - hTERT-RPE1 [nTPM]":"573.3","Cell RNA - HUVEC TERT2 [nTPM]":"305.0","Cell RNA - JURKAT [nTPM]":"14.8","Cell RNA - K-562 [nTPM]":"97.6","Cell RNA - Karpas-707 [nTPM]":"30.9","Cell RNA - LHCN-M2 [nTPM]":"180.2","Cell RNA - MCF7 [nTPM]":"71.1","Cell RNA - MOLT-4 [nTPM]":"5.7","Cell RNA - NB-4 [nTPM]":"58.6","Cell RNA - NTERA-2 [nTPM]":"22.9","Cell RNA - OE19 [nTPM]":"115.4","Cell RNA - PC-3 [nTPM]":"131.6","Cell RNA - REH [nTPM]":"25.8","Cell RNA - RH-30 [nTPM]":"100.0","Cell RNA - RPMI-8226 [nTPM]":"141.0","Cell RNA - RPTEC TERT1 [nTPM]":"98.7","Cell RNA - RT4 [nTPM]":"24.3","Cell RNA - SCLC-21H [nTPM]":"19.2","Cell RNA - SH-SY5Y [nTPM]":"77.7","Cell RNA - SiHa [nTPM]":"137.3","Cell RNA - SK-BR-3 [nTPM]":"97.4","Cell RNA - SK-MEL-30 [nTPM]":"164.8","Cell RNA - SuSa [nTPM]":"80.4","Cell RNA - T-47d [nTPM]":"48.3","Cell RNA - THP-1 [nTPM]":"55.9","Cell RNA - TIME [nTPM]":"298.7","Cell RNA - U-138 MG [nTPM]":"190.1","Cell RNA - U-2 OS [nTPM]":"141.6","Cell RNA - U-2197 [nTPM]":"236.3","Cell RNA - U-251 MG [nTPM]":"161.9","Cell RNA - U-266\/70 [nTPM]":"71.4","Cell RNA - U-266\/84 [nTPM]":"123.7","Cell RNA - U-698 [nTPM]":"38.7","Cell RNA - U-87 MG [nTPM]":"425.1","Cell RNA - U-937 [nTPM]":"75.5","Cell RNA - WM-115 [nTPM]":"316.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"40.3","Blood RNA - eosinophil [nTPM]":"2.0","Blood RNA - gdT-cell [nTPM]":"17.3","Blood RNA - intermediate monocyte [nTPM]":"34.4","Blood RNA - MAIT T-cell [nTPM]":"3.1","Blood RNA - memory B-cell [nTPM]":"1.7","Blood RNA - memory CD4 T-cell [nTPM]":"3.0","Blood RNA - memory CD8 T-cell [nTPM]":"8.4","Blood RNA - myeloid DC [nTPM]":"32.7","Blood RNA - naive B-cell [nTPM]":"3.4","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"6.4","Blood RNA - neutrophil [nTPM]":"35.5","Blood RNA - NK-cell [nTPM]":"5.4","Blood RNA - non-classical monocyte [nTPM]":"32.3","Blood RNA - plasmacytoid DC [nTPM]":"4.9","Blood RNA - T-reg [nTPM]":"2.0","Blood RNA - total PBMC [nTPM]":"22.6","Brain RNA - amygdala [nTPM]":"46.3","Brain RNA - basal ganglia [nTPM]":"51.2","Brain RNA - cerebellum [nTPM]":"48.6","Brain RNA - cerebral cortex [nTPM]":"56.6","Brain RNA - hippocampal formation [nTPM]":"44.5","Brain RNA - hypothalamus [nTPM]":"47.4","Brain RNA - medulla oblongata [nTPM]":"49.6","Brain RNA - midbrain [nTPM]":"50.8","Brain RNA - pons [nTPM]":"52.4","Brain RNA - spinal cord [nTPM]":"44.8","Brain RNA - thalamus [nTPM]":"52.2","Brain RNA - white matter [nTPM]":"53.1","Single Cell Type RNA - Adipocytes [nTPM]":"19.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.9","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"3.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"5.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"8.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"39.7","Single Cell Type RNA - dendritic cells [nTPM]":"8.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"30.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"62.2","Single Cell Type RNA - Endothelial cells [nTPM]":"33.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"3.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"236.8","Single Cell Type RNA - Fibroblasts [nTPM]":"47.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"20.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"36.8","Single Cell Type RNA - Hepatocytes [nTPM]":"37.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"46.3","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.5","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"26.5","Single Cell Type RNA - Langerhans cells [nTPM]":"8.3","Single Cell Type RNA - Late spermatids [nTPM]":"2.4","Single Cell Type RNA - Leydig cells [nTPM]":"44.4","Single Cell Type RNA - Macrophages [nTPM]":"16.3","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"17.9","Single Cell Type RNA - Muller glia cells [nTPM]":"7.9","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.4","Single Cell Type RNA - Paneth cells [nTPM]":"15.4","Single Cell Type RNA - Peritubular cells [nTPM]":"24.5","Single Cell Type RNA - Plasma cells [nTPM]":"19.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"41.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.1","Single Cell Type RNA - Sertoli cells [nTPM]":"105.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"77.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"47.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"3.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"33.7","Single Cell Type RNA - T-cells [nTPM]":"5.5","Single Cell Type RNA - Theca cells [nTPM]":"37.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.6","Single Cell Type RNA - Urothelial cells [nTPM]":"3.9"},{"Gene":"PLOD2","Gene synonym":["LH2"],"Ensembl":"ENSG00000152952","Gene description":"Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2","Uniprot":["O00469"],"Chromosome":"3","Position":"146069440-146163653","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Dioxygenase","Oxidoreductase"],"Disease involvement":["Disease variant","Osteogenesis imperfecta"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"130.9","Basal respiratory cells":"115.1","Distal enterocytes":"143.7","Extravillous trophoblasts":"130.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HBF TERT88":"636.0","hTERT-RPE1":"723.8","U-87 MG":"566.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025898","HPA069126"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"21000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":["Nucleoli","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB025898":null,"HPA069126":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.97e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.64e-10"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.42e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.99e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.83e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-3"},"Tissue RNA - adipose tissue [nTPM]":"63.1","Tissue RNA - adrenal gland [nTPM]":"20.1","Tissue RNA - amygdala [nTPM]":"13.4","Tissue RNA - appendix [nTPM]":"35.6","Tissue RNA - basal ganglia [nTPM]":"14.5","Tissue RNA - bone marrow [nTPM]":"1.1","Tissue RNA - breast [nTPM]":"18.6","Tissue RNA - cerebellum [nTPM]":"15.1","Tissue RNA - cerebral cortex [nTPM]":"17.2","Tissue RNA - cervix [nTPM]":"10.2","Tissue RNA - choroid plexus [nTPM]":"19.4","Tissue RNA - colon [nTPM]":"36.2","Tissue RNA - duodenum [nTPM]":"42.2","Tissue RNA - endometrium 1 [nTPM]":"23.5","Tissue RNA - epididymis [nTPM]":"13.4","Tissue RNA - esophagus [nTPM]":"18.2","Tissue RNA - fallopian tube [nTPM]":"11.4","Tissue RNA - gallbladder [nTPM]":"41.5","Tissue RNA - heart muscle [nTPM]":"22.1","Tissue RNA - hippocampal formation [nTPM]":"13.3","Tissue RNA - hypothalamus [nTPM]":"15.1","Tissue RNA - kidney [nTPM]":"26.1","Tissue RNA - liver [nTPM]":"57.3","Tissue RNA - lung [nTPM]":"12.9","Tissue RNA - lymph node [nTPM]":"3.8","Tissue RNA - medulla oblongata [nTPM]":"23.1","Tissue RNA - midbrain [nTPM]":"18.1","Tissue RNA - ovary [nTPM]":"20.5","Tissue RNA - pancreas [nTPM]":"18.7","Tissue RNA - parathyroid gland [nTPM]":"16.5","Tissue RNA - pituitary gland [nTPM]":"7.9","Tissue RNA - placenta [nTPM]":"80.6","Tissue RNA - pons [nTPM]":"16.3","Tissue RNA - prostate [nTPM]":"13.2","Tissue RNA - rectum [nTPM]":"29.9","Tissue RNA - retina [nTPM]":"56.6","Tissue RNA - salivary gland [nTPM]":"9.5","Tissue RNA - seminal vesicle [nTPM]":"16.2","Tissue RNA - skeletal muscle [nTPM]":"3.0","Tissue RNA - skin 1 [nTPM]":"3.9","Tissue RNA - small intestine [nTPM]":"35.0","Tissue RNA - smooth muscle [nTPM]":"46.8","Tissue RNA - spinal cord [nTPM]":"17.8","Tissue RNA - spleen [nTPM]":"5.4","Tissue RNA - stomach 1 [nTPM]":"20.1","Tissue RNA - testis [nTPM]":"8.5","Tissue RNA - thalamus [nTPM]":"20.6","Tissue RNA - thymus [nTPM]":"10.5","Tissue RNA - thyroid gland [nTPM]":"90.0","Tissue RNA - tongue [nTPM]":"3.9","Tissue RNA - tonsil [nTPM]":"5.5","Tissue RNA - urinary bladder [nTPM]":"25.7","Tissue RNA - vagina [nTPM]":"10.0","Tissue RNA - white matter [nTPM]":"17.6","Cell RNA - A-431 [nTPM]":"134.5","Cell RNA - A549 [nTPM]":"94.3","Cell RNA - AF22 [nTPM]":"29.0","Cell RNA - AN3-CA [nTPM]":"9.5","Cell RNA - ASC diff [nTPM]":"102.5","Cell RNA - ASC TERT1 [nTPM]":"109.6","Cell RNA - BEWO [nTPM]":"73.2","Cell RNA - BJ [nTPM]":"465.5","Cell RNA - BJ hTERT+ [nTPM]":"141.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"247.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"463.0","Cell RNA - CACO-2 [nTPM]":"7.2","Cell RNA - CAPAN-2 [nTPM]":"13.4","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"88.8","Cell RNA - fHDF\/TERT166 [nTPM]":"79.5","Cell RNA - GAMG [nTPM]":"113.1","Cell RNA - HaCaT [nTPM]":"27.8","Cell RNA - HAP1 [nTPM]":"34.0","Cell RNA - HBEC3-KT [nTPM]":"400.5","Cell RNA - HBF TERT88 [nTPM]":"636.0","Cell RNA - HDLM-2 [nTPM]":"0.6","Cell RNA - HEK 293 [nTPM]":"53.5","Cell RNA - HEL [nTPM]":"33.3","Cell RNA - HeLa [nTPM]":"84.3","Cell RNA - Hep G2 [nTPM]":"66.9","Cell RNA - HHSteC [nTPM]":"262.5","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"192.9","Cell RNA - hTCEpi [nTPM]":"56.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"215.2","Cell RNA - hTERT-HME1 [nTPM]":"104.1","Cell RNA - hTERT-RPE1 [nTPM]":"723.8","Cell RNA - HUVEC TERT2 [nTPM]":"347.7","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"45.1","Cell RNA - Karpas-707 [nTPM]":"1.8","Cell RNA - LHCN-M2 [nTPM]":"441.6","Cell RNA - MCF7 [nTPM]":"48.8","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"18.5","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"40.0","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"19.2","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"105.0","Cell RNA - RT4 [nTPM]":"6.5","Cell RNA - SCLC-21H [nTPM]":"14.5","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"370.3","Cell RNA - SK-BR-3 [nTPM]":"39.4","Cell RNA - SK-MEL-30 [nTPM]":"39.9","Cell RNA - SuSa [nTPM]":"135.1","Cell RNA - T-47d [nTPM]":"107.5","Cell RNA - THP-1 [nTPM]":"4.2","Cell RNA - TIME [nTPM]":"440.4","Cell RNA - U-138 MG [nTPM]":"304.2","Cell RNA - U-2 OS [nTPM]":"92.2","Cell RNA - U-2197 [nTPM]":"97.8","Cell RNA - U-251 MG [nTPM]":"280.7","Cell RNA - U-266\/70 [nTPM]":"138.9","Cell RNA - U-266\/84 [nTPM]":"20.9","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"566.5","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"55.6","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"13.4","Brain RNA - basal ganglia [nTPM]":"14.5","Brain RNA - cerebellum [nTPM]":"15.1","Brain RNA - cerebral cortex [nTPM]":"17.2","Brain RNA - hippocampal formation [nTPM]":"13.3","Brain RNA - hypothalamus [nTPM]":"15.1","Brain RNA - medulla oblongata [nTPM]":"23.1","Brain RNA - midbrain [nTPM]":"18.1","Brain RNA - pons [nTPM]":"16.3","Brain RNA - spinal cord [nTPM]":"17.8","Brain RNA - thalamus [nTPM]":"20.6","Brain RNA - white matter [nTPM]":"17.6","Single Cell Type RNA - Adipocytes [nTPM]":"29.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.4","Single Cell Type RNA - Astrocytes [nTPM]":"130.9","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"115.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"30.1","Single Cell Type RNA - Bipolar cells [nTPM]":"17.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"44.3","Single Cell Type RNA - Club cells [nTPM]":"47.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"143.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"64.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"35.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.8","Single Cell Type RNA - Endothelial cells [nTPM]":"24.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.8","Single Cell Type RNA - Erythroid cells [nTPM]":"4.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"53.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"130.6","Single Cell Type RNA - Fibroblasts [nTPM]":"68.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"38.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"42.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.0","Single Cell Type RNA - Hepatocytes [nTPM]":"65.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"46.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.5","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"2.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"13.1","Single Cell Type RNA - Macrophages [nTPM]":"3.0","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"53.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"64.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"82.4","Single Cell Type RNA - Paneth cells [nTPM]":"48.8","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"1.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"50.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.7","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"36.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"47.2","Single Cell Type RNA - Spermatocytes [nTPM]":"11.0","Single Cell Type RNA - Spermatogonia [nTPM]":"18.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"27.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"18.7","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"24.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"25.1","Single Cell Type RNA - Urothelial cells [nTPM]":"5.6"},{"Gene":"PLOD3","Gene synonym":["LH3"],"Ensembl":"ENSG00000106397","Gene description":"Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3","Uniprot":["O60568"],"Chromosome":"7","Position":"101205977-101218420","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Dioxygenase","Glycosyltransferase","Multifunctional enzyme","Oxidoreductase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"115.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"20.3","monocytes":"22.5","T-cells":"12.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"695.6","WM-115":"680.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001236"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1600000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA001236":"AB_1855474"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.91e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.26e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.26e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.00e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.52e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.87e-2"},"Tissue RNA - adipose tissue [nTPM]":"41.9","Tissue RNA - adrenal gland [nTPM]":"27.3","Tissue RNA - amygdala [nTPM]":"43.6","Tissue RNA - appendix [nTPM]":"22.9","Tissue RNA - basal ganglia [nTPM]":"53.2","Tissue RNA - bone marrow [nTPM]":"19.6","Tissue RNA - breast [nTPM]":"32.8","Tissue RNA - cerebellum [nTPM]":"54.9","Tissue RNA - cerebral cortex [nTPM]":"58.5","Tissue RNA - cervix [nTPM]":"33.3","Tissue RNA - choroid plexus [nTPM]":"46.8","Tissue RNA - colon [nTPM]":"37.8","Tissue RNA - duodenum [nTPM]":"25.7","Tissue RNA - endometrium 1 [nTPM]":"38.9","Tissue RNA - epididymis [nTPM]":"11.7","Tissue RNA - esophagus [nTPM]":"12.2","Tissue RNA - fallopian tube [nTPM]":"32.5","Tissue RNA - gallbladder [nTPM]":"18.8","Tissue RNA - heart muscle [nTPM]":"42.6","Tissue RNA - hippocampal formation [nTPM]":"43.6","Tissue RNA - hypothalamus [nTPM]":"46.3","Tissue RNA - kidney [nTPM]":"36.3","Tissue RNA - liver [nTPM]":"54.1","Tissue RNA - lung [nTPM]":"37.5","Tissue RNA - lymph node [nTPM]":"14.6","Tissue RNA - medulla oblongata [nTPM]":"61.1","Tissue RNA - midbrain [nTPM]":"52.3","Tissue RNA - ovary [nTPM]":"26.3","Tissue RNA - pancreas [nTPM]":"41.8","Tissue RNA - parathyroid gland [nTPM]":"21.5","Tissue RNA - pituitary gland [nTPM]":"27.1","Tissue RNA - placenta [nTPM]":"35.0","Tissue RNA - pons [nTPM]":"58.9","Tissue RNA - prostate [nTPM]":"24.2","Tissue RNA - rectum [nTPM]":"15.3","Tissue RNA - retina [nTPM]":"3.9","Tissue RNA - salivary gland [nTPM]":"19.4","Tissue RNA - seminal vesicle [nTPM]":"18.6","Tissue RNA - skeletal muscle [nTPM]":"15.3","Tissue RNA - skin 1 [nTPM]":"19.1","Tissue RNA - small intestine [nTPM]":"35.9","Tissue RNA - smooth muscle [nTPM]":"26.0","Tissue RNA - spinal cord [nTPM]":"49.4","Tissue RNA - spleen [nTPM]":"35.3","Tissue RNA - stomach 1 [nTPM]":"30.0","Tissue RNA - testis [nTPM]":"12.9","Tissue RNA - thalamus [nTPM]":"51.7","Tissue RNA - thymus [nTPM]":"8.0","Tissue RNA - thyroid gland [nTPM]":"25.3","Tissue RNA - tongue [nTPM]":"11.8","Tissue RNA - tonsil [nTPM]":"7.5","Tissue RNA - urinary bladder [nTPM]":"35.2","Tissue RNA - vagina [nTPM]":"25.2","Tissue RNA - white matter [nTPM]":"71.9","Cell RNA - A-431 [nTPM]":"71.7","Cell RNA - A549 [nTPM]":"62.4","Cell RNA - AF22 [nTPM]":"27.1","Cell RNA - AN3-CA [nTPM]":"168.2","Cell RNA - ASC diff [nTPM]":"116.2","Cell RNA - ASC TERT1 [nTPM]":"83.9","Cell RNA - BEWO [nTPM]":"51.4","Cell RNA - BJ [nTPM]":"125.5","Cell RNA - BJ hTERT+ [nTPM]":"135.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"122.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"88.6","Cell RNA - CACO-2 [nTPM]":"98.0","Cell RNA - CAPAN-2 [nTPM]":"89.0","Cell RNA - Daudi [nTPM]":"5.6","Cell RNA - EFO-21 [nTPM]":"140.2","Cell RNA - fHDF\/TERT166 [nTPM]":"211.4","Cell RNA - GAMG [nTPM]":"100.7","Cell RNA - HaCaT [nTPM]":"83.0","Cell RNA - HAP1 [nTPM]":"50.0","Cell RNA - HBEC3-KT [nTPM]":"72.0","Cell RNA - HBF TERT88 [nTPM]":"31.2","Cell RNA - HDLM-2 [nTPM]":"37.8","Cell RNA - HEK 293 [nTPM]":"23.8","Cell RNA - HEL [nTPM]":"7.2","Cell RNA - HeLa [nTPM]":"70.7","Cell RNA - Hep G2 [nTPM]":"97.3","Cell RNA - HHSteC [nTPM]":"157.6","Cell RNA - HL-60 [nTPM]":"31.5","Cell RNA - HMC-1 [nTPM]":"57.4","Cell RNA - HSkMC [nTPM]":"90.8","Cell RNA - hTCEpi [nTPM]":"67.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"71.6","Cell RNA - hTERT-HME1 [nTPM]":"55.4","Cell RNA - hTERT-RPE1 [nTPM]":"120.2","Cell RNA - HUVEC TERT2 [nTPM]":"110.9","Cell RNA - JURKAT [nTPM]":"4.6","Cell RNA - K-562 [nTPM]":"68.4","Cell RNA - Karpas-707 [nTPM]":"695.6","Cell RNA - LHCN-M2 [nTPM]":"84.2","Cell RNA - MCF7 [nTPM]":"194.5","Cell RNA - MOLT-4 [nTPM]":"3.4","Cell RNA - NB-4 [nTPM]":"72.1","Cell RNA - NTERA-2 [nTPM]":"53.5","Cell RNA - OE19 [nTPM]":"120.5","Cell RNA - PC-3 [nTPM]":"94.9","Cell RNA - REH [nTPM]":"21.8","Cell RNA - RH-30 [nTPM]":"35.1","Cell RNA - RPMI-8226 [nTPM]":"108.3","Cell RNA - RPTEC TERT1 [nTPM]":"42.0","Cell RNA - RT4 [nTPM]":"19.1","Cell RNA - SCLC-21H [nTPM]":"21.2","Cell RNA - SH-SY5Y [nTPM]":"116.0","Cell RNA - SiHa [nTPM]":"81.1","Cell RNA - SK-BR-3 [nTPM]":"116.2","Cell RNA - SK-MEL-30 [nTPM]":"288.1","Cell RNA - SuSa [nTPM]":"66.8","Cell RNA - T-47d [nTPM]":"21.9","Cell RNA - THP-1 [nTPM]":"105.2","Cell RNA - TIME [nTPM]":"100.5","Cell RNA - U-138 MG [nTPM]":"188.1","Cell RNA - U-2 OS [nTPM]":"94.9","Cell RNA - U-2197 [nTPM]":"228.1","Cell RNA - U-251 MG [nTPM]":"155.0","Cell RNA - U-266\/70 [nTPM]":"38.5","Cell RNA - U-266\/84 [nTPM]":"75.9","Cell RNA - U-698 [nTPM]":"5.2","Cell RNA - U-87 MG [nTPM]":"112.4","Cell RNA - U-937 [nTPM]":"74.2","Cell RNA - WM-115 [nTPM]":"680.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"18.1","Blood RNA - eosinophil [nTPM]":"4.4","Blood RNA - gdT-cell [nTPM]":"12.6","Blood RNA - intermediate monocyte [nTPM]":"21.8","Blood RNA - MAIT T-cell [nTPM]":"10.9","Blood RNA - memory B-cell [nTPM]":"3.7","Blood RNA - memory CD4 T-cell [nTPM]":"9.3","Blood RNA - memory CD8 T-cell [nTPM]":"8.3","Blood RNA - myeloid DC [nTPM]":"16.5","Blood RNA - naive B-cell [nTPM]":"2.2","Blood RNA - naive CD4 T-cell [nTPM]":"4.1","Blood RNA - naive CD8 T-cell [nTPM]":"4.5","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"3.6","Blood RNA - non-classical monocyte [nTPM]":"22.5","Blood RNA - plasmacytoid DC [nTPM]":"20.3","Blood RNA - T-reg [nTPM]":"6.7","Blood RNA - total PBMC [nTPM]":"9.5","Brain RNA - amygdala [nTPM]":"43.6","Brain RNA - basal ganglia [nTPM]":"53.2","Brain RNA - cerebellum [nTPM]":"54.9","Brain RNA - cerebral cortex [nTPM]":"58.5","Brain RNA - hippocampal formation [nTPM]":"43.6","Brain RNA - hypothalamus [nTPM]":"46.3","Brain RNA - medulla oblongata [nTPM]":"61.1","Brain RNA - midbrain [nTPM]":"52.3","Brain RNA - pons [nTPM]":"58.9","Brain RNA - spinal cord [nTPM]":"49.4","Brain RNA - thalamus [nTPM]":"51.7","Brain RNA - white matter [nTPM]":"71.9","Single Cell Type RNA - Adipocytes [nTPM]":"34.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.7","Single Cell Type RNA - Astrocytes [nTPM]":"11.1","Single Cell Type RNA - B-cells [nTPM]":"9.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"5.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"8.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.4","Single Cell Type RNA - dendritic cells [nTPM]":"22.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"37.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"40.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.9","Single Cell Type RNA - Endothelial cells [nTPM]":"28.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.2","Single Cell Type RNA - Erythroid cells [nTPM]":"19.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"31.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"71.6","Single Cell Type RNA - Fibroblasts [nTPM]":"34.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.5","Single Cell Type RNA - granulocytes [nTPM]":"19.7","Single Cell Type RNA - Granulosa cells [nTPM]":"25.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.7","Single Cell Type RNA - Hepatocytes [nTPM]":"18.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"50.1","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"23.3","Single Cell Type RNA - Langerhans cells [nTPM]":"18.3","Single Cell Type RNA - Late spermatids [nTPM]":"2.1","Single Cell Type RNA - Leydig cells [nTPM]":"26.1","Single Cell Type RNA - Macrophages [nTPM]":"23.2","Single Cell Type RNA - Melanocytes [nTPM]":"62.2","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"18.9","Single Cell Type RNA - Muller glia cells [nTPM]":"7.7","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"33.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"36.1","Single Cell Type RNA - Paneth cells [nTPM]":"37.8","Single Cell Type RNA - Peritubular cells [nTPM]":"14.7","Single Cell Type RNA - Plasma cells [nTPM]":"19.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"45.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.3","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"29.8","Single Cell Type RNA - Spermatocytes [nTPM]":"8.9","Single Cell Type RNA - Spermatogonia [nTPM]":"12.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"18.9","Single Cell Type RNA - T-cells [nTPM]":"12.5","Single Cell Type RNA - Theca cells [nTPM]":"18.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"27.3","Single Cell Type RNA - Urothelial cells [nTPM]":"5.2"},{"Gene":"PMM2","Gene synonym":["CDG1","CDG1a","CDGS","PMI","PMI1"],"Ensembl":"ENSG00000140650","Gene description":"Phosphomannomutase 2","Uniprot":["O15305"],"Chromosome":"16","Position":"8788823-8849325","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Isomerase"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"basophil":"210.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"granulocytes":"210.5"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040852","HPA063649"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"21000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA040852":"AB_10794069","HPA063649":"AB_2685074"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.04e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.97e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Tissue RNA - adipose tissue [nTPM]":"18.5","Tissue RNA - adrenal gland [nTPM]":"18.3","Tissue RNA - amygdala [nTPM]":"3.3","Tissue RNA - appendix [nTPM]":"15.1","Tissue RNA - basal ganglia [nTPM]":"4.6","Tissue RNA - bone marrow [nTPM]":"6.4","Tissue RNA - breast [nTPM]":"16.7","Tissue RNA - cerebellum [nTPM]":"3.3","Tissue RNA - cerebral cortex [nTPM]":"4.2","Tissue RNA - cervix [nTPM]":"13.7","Tissue RNA - choroid plexus [nTPM]":"8.4","Tissue RNA - colon [nTPM]":"26.0","Tissue RNA - duodenum [nTPM]":"25.0","Tissue RNA - endometrium 1 [nTPM]":"10.6","Tissue RNA - epididymis [nTPM]":"11.9","Tissue RNA - esophagus [nTPM]":"29.0","Tissue RNA - fallopian tube [nTPM]":"10.7","Tissue RNA - gallbladder [nTPM]":"10.6","Tissue RNA - heart muscle [nTPM]":"13.2","Tissue RNA - hippocampal formation [nTPM]":"3.8","Tissue RNA - hypothalamus [nTPM]":"3.5","Tissue RNA - kidney [nTPM]":"16.7","Tissue RNA - liver [nTPM]":"51.8","Tissue RNA - lung [nTPM]":"13.8","Tissue RNA - lymph node [nTPM]":"13.7","Tissue RNA - medulla oblongata [nTPM]":"3.6","Tissue RNA - midbrain [nTPM]":"3.7","Tissue RNA - ovary [nTPM]":"7.5","Tissue RNA - pancreas [nTPM]":"36.5","Tissue RNA - parathyroid gland [nTPM]":"10.2","Tissue RNA - pituitary gland [nTPM]":"12.1","Tissue RNA - placenta [nTPM]":"15.5","Tissue RNA - pons [nTPM]":"3.5","Tissue RNA - prostate [nTPM]":"14.2","Tissue RNA - rectum [nTPM]":"26.0","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"22.6","Tissue RNA - seminal vesicle [nTPM]":"7.4","Tissue RNA - skeletal muscle [nTPM]":"9.7","Tissue RNA - skin 1 [nTPM]":"16.2","Tissue RNA - small intestine [nTPM]":"21.3","Tissue RNA - smooth muscle [nTPM]":"12.5","Tissue RNA - spinal cord [nTPM]":"3.5","Tissue RNA - spleen [nTPM]":"14.0","Tissue RNA - stomach 1 [nTPM]":"19.6","Tissue RNA - testis [nTPM]":"4.5","Tissue RNA - thalamus [nTPM]":"3.9","Tissue RNA - thymus [nTPM]":"9.6","Tissue RNA - thyroid gland [nTPM]":"11.3","Tissue RNA - tongue [nTPM]":"5.9","Tissue RNA - tonsil [nTPM]":"14.2","Tissue RNA - urinary bladder [nTPM]":"21.7","Tissue RNA - vagina [nTPM]":"15.7","Tissue RNA - white matter [nTPM]":"3.6","Cell RNA - A-431 [nTPM]":"26.1","Cell RNA - A549 [nTPM]":"56.5","Cell RNA - AF22 [nTPM]":"12.3","Cell RNA - AN3-CA [nTPM]":"32.7","Cell RNA - ASC diff [nTPM]":"21.8","Cell RNA - ASC TERT1 [nTPM]":"33.7","Cell RNA - BEWO [nTPM]":"27.4","Cell RNA - BJ [nTPM]":"39.8","Cell RNA - BJ hTERT+ [nTPM]":"47.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"38.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"41.6","Cell RNA - CACO-2 [nTPM]":"42.5","Cell RNA - CAPAN-2 [nTPM]":"31.5","Cell RNA - Daudi [nTPM]":"41.0","Cell RNA - EFO-21 [nTPM]":"16.3","Cell RNA - fHDF\/TERT166 [nTPM]":"69.4","Cell RNA - GAMG [nTPM]":"20.2","Cell RNA - HaCaT [nTPM]":"35.1","Cell RNA - HAP1 [nTPM]":"25.3","Cell RNA - HBEC3-KT [nTPM]":"48.5","Cell RNA - HBF TERT88 [nTPM]":"39.2","Cell RNA - HDLM-2 [nTPM]":"30.7","Cell RNA - HEK 293 [nTPM]":"29.0","Cell RNA - HEL [nTPM]":"13.6","Cell RNA - HeLa [nTPM]":"33.0","Cell RNA - Hep G2 [nTPM]":"73.8","Cell RNA - HHSteC [nTPM]":"40.4","Cell RNA - HL-60 [nTPM]":"36.9","Cell RNA - HMC-1 [nTPM]":"31.6","Cell RNA - HSkMC [nTPM]":"50.4","Cell RNA - hTCEpi [nTPM]":"33.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"41.1","Cell RNA - hTERT-HME1 [nTPM]":"37.9","Cell RNA - hTERT-RPE1 [nTPM]":"18.1","Cell RNA - HUVEC TERT2 [nTPM]":"40.1","Cell RNA - JURKAT [nTPM]":"24.5","Cell RNA - K-562 [nTPM]":"18.9","Cell RNA - Karpas-707 [nTPM]":"39.6","Cell RNA - LHCN-M2 [nTPM]":"26.0","Cell RNA - MCF7 [nTPM]":"68.3","Cell RNA - MOLT-4 [nTPM]":"37.9","Cell RNA - NB-4 [nTPM]":"33.9","Cell RNA - NTERA-2 [nTPM]":"52.8","Cell RNA - OE19 [nTPM]":"60.0","Cell RNA - PC-3 [nTPM]":"35.8","Cell RNA - REH [nTPM]":"47.2","Cell RNA - RH-30 [nTPM]":"27.4","Cell RNA - RPMI-8226 [nTPM]":"82.8","Cell RNA - RPTEC TERT1 [nTPM]":"43.5","Cell RNA - RT4 [nTPM]":"45.0","Cell RNA - SCLC-21H [nTPM]":"23.5","Cell RNA - SH-SY5Y [nTPM]":"43.7","Cell RNA - SiHa [nTPM]":"32.7","Cell RNA - SK-BR-3 [nTPM]":"71.4","Cell RNA - SK-MEL-30 [nTPM]":"23.9","Cell RNA - SuSa [nTPM]":"19.5","Cell RNA - T-47d [nTPM]":"46.4","Cell RNA - THP-1 [nTPM]":"31.7","Cell RNA - TIME [nTPM]":"47.7","Cell RNA - U-138 MG [nTPM]":"27.8","Cell RNA - U-2 OS [nTPM]":"31.5","Cell RNA - U-2197 [nTPM]":"76.6","Cell RNA - U-251 MG [nTPM]":"39.5","Cell RNA - U-266\/70 [nTPM]":"48.2","Cell RNA - U-266\/84 [nTPM]":"43.3","Cell RNA - U-698 [nTPM]":"51.5","Cell RNA - U-87 MG [nTPM]":"23.4","Cell RNA - U-937 [nTPM]":"45.5","Cell RNA - WM-115 [nTPM]":"38.0","Blood RNA - basophil [nTPM]":"210.5","Blood RNA - classical monocyte [nTPM]":"16.5","Blood RNA - eosinophil [nTPM]":"3.2","Blood RNA - gdT-cell [nTPM]":"7.9","Blood RNA - intermediate monocyte [nTPM]":"13.0","Blood RNA - MAIT T-cell [nTPM]":"11.7","Blood RNA - memory B-cell [nTPM]":"9.5","Blood RNA - memory CD4 T-cell [nTPM]":"7.0","Blood RNA - memory CD8 T-cell [nTPM]":"10.2","Blood RNA - myeloid DC [nTPM]":"12.1","Blood RNA - naive B-cell [nTPM]":"7.8","Blood RNA - naive CD4 T-cell [nTPM]":"7.7","Blood RNA - naive CD8 T-cell [nTPM]":"7.5","Blood RNA - neutrophil [nTPM]":"26.5","Blood RNA - NK-cell [nTPM]":"6.2","Blood RNA - non-classical monocyte [nTPM]":"8.4","Blood RNA - plasmacytoid DC [nTPM]":"10.9","Blood RNA - T-reg [nTPM]":"5.7","Blood RNA - total PBMC [nTPM]":"10.9","Brain RNA - amygdala [nTPM]":"3.3","Brain RNA - basal ganglia [nTPM]":"4.6","Brain RNA - cerebellum [nTPM]":"3.3","Brain RNA - cerebral cortex [nTPM]":"4.2","Brain RNA - hippocampal formation [nTPM]":"3.8","Brain RNA - hypothalamus [nTPM]":"3.5","Brain RNA - medulla oblongata [nTPM]":"3.6","Brain RNA - midbrain [nTPM]":"3.7","Brain RNA - pons [nTPM]":"3.5","Brain RNA - spinal cord [nTPM]":"3.5","Brain RNA - thalamus [nTPM]":"3.9","Brain RNA - white matter [nTPM]":"3.6","Single Cell Type RNA - Adipocytes [nTPM]":"16.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"24.1","Single Cell Type RNA - Astrocytes [nTPM]":"12.7","Single Cell Type RNA - B-cells [nTPM]":"18.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"4.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"28.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.9","Single Cell Type RNA - dendritic cells [nTPM]":"11.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"16.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"32.0","Single Cell Type RNA - Endothelial cells [nTPM]":"11.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.7","Single Cell Type RNA - Erythroid cells [nTPM]":"9.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"29.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"28.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.9","Single Cell Type RNA - Fibroblasts [nTPM]":"16.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"38.5","Single Cell Type RNA - granulocytes [nTPM]":"22.8","Single Cell Type RNA - Granulosa cells [nTPM]":"12.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"12.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.5","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"26.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.2","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.7","Single Cell Type RNA - Langerhans cells [nTPM]":"1.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"6.2","Single Cell Type RNA - Macrophages [nTPM]":"10.4","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"9.6","Single Cell Type RNA - Muller glia cells [nTPM]":"2.5","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"23.3","Single Cell Type RNA - Paneth cells [nTPM]":"9.7","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"49.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.8","Single Cell Type RNA - Spermatocytes [nTPM]":"2.0","Single Cell Type RNA - Spermatogonia [nTPM]":"4.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"27.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.7","Single Cell Type RNA - T-cells [nTPM]":"16.0","Single Cell Type RNA - Theca cells [nTPM]":"13.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.6","Single Cell Type RNA - Urothelial cells [nTPM]":"14.9"},{"Gene":"PMP22","Gene synonym":["CMT1A","GAS3","HMSNIA","HNPP","Sp110"],"Ensembl":"ENSG00000109099","Gene description":"Peripheral myelin protein 22","Uniprot":["Q01453"],"Chromosome":"17","Position":"15229773-15272292","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Charcot-Marie-Tooth disease","Deafness","Dejerine-Sottas syndrome","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Fibroblasts":"404.1","Hofbauer cells":"558.3","Leydig cells":"324.3","Melanocytes":"343.3","Proximal enterocytes":"580.6","Skeletal myocytes":"288.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"32.2","eosinophil":"43.0","plasmacytoid DC":"23.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"22","RNA blood lineage specific nTPM":{"dendritic cells":"23.8","granulocytes":"43.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"383.5","HMC-1":"263.7","SuSa":"333.9","WM-115":"448.8"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.73e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Tissue RNA - adipose tissue [nTPM]":"275.6","Tissue RNA - adrenal gland [nTPM]":"45.4","Tissue RNA - amygdala [nTPM]":"113.6","Tissue RNA - appendix [nTPM]":"55.1","Tissue RNA - basal ganglia [nTPM]":"161.0","Tissue RNA - bone marrow [nTPM]":"4.9","Tissue RNA - breast [nTPM]":"184.5","Tissue RNA - cerebellum [nTPM]":"153.2","Tissue RNA - cerebral cortex [nTPM]":"140.7","Tissue RNA - cervix [nTPM]":"192.2","Tissue RNA - choroid plexus [nTPM]":"77.9","Tissue RNA - colon [nTPM]":"212.2","Tissue RNA - duodenum [nTPM]":"41.7","Tissue RNA - endometrium 1 [nTPM]":"142.1","Tissue RNA - epididymis [nTPM]":"36.5","Tissue RNA - esophagus [nTPM]":"68.2","Tissue RNA - fallopian tube [nTPM]":"163.4","Tissue RNA - gallbladder [nTPM]":"106.5","Tissue RNA - heart muscle [nTPM]":"167.6","Tissue RNA - hippocampal formation [nTPM]":"113.5","Tissue RNA - hypothalamus [nTPM]":"129.0","Tissue RNA - kidney [nTPM]":"53.5","Tissue RNA - liver [nTPM]":"11.7","Tissue RNA - lung [nTPM]":"208.4","Tissue RNA - lymph node [nTPM]":"27.8","Tissue RNA - medulla oblongata [nTPM]":"163.3","Tissue RNA - midbrain [nTPM]":"144.2","Tissue RNA - ovary [nTPM]":"102.9","Tissue RNA - pancreas [nTPM]":"22.8","Tissue RNA - parathyroid gland [nTPM]":"10.8","Tissue RNA - pituitary gland [nTPM]":"26.3","Tissue RNA - placenta [nTPM]":"201.9","Tissue RNA - pons [nTPM]":"159.9","Tissue RNA - prostate [nTPM]":"81.2","Tissue RNA - rectum [nTPM]":"74.7","Tissue RNA - retina [nTPM]":"6.5","Tissue RNA - salivary gland [nTPM]":"77.5","Tissue RNA - seminal vesicle [nTPM]":"80.6","Tissue RNA - skeletal muscle [nTPM]":"252.4","Tissue RNA - skin 1 [nTPM]":"112.7","Tissue RNA - small intestine [nTPM]":"239.1","Tissue RNA - smooth muscle [nTPM]":"122.0","Tissue RNA - spinal cord [nTPM]":"135.0","Tissue RNA - spleen [nTPM]":"27.9","Tissue RNA - stomach 1 [nTPM]":"96.2","Tissue RNA - testis [nTPM]":"20.7","Tissue RNA - thalamus [nTPM]":"141.1","Tissue RNA - thymus [nTPM]":"17.3","Tissue RNA - thyroid gland [nTPM]":"95.3","Tissue RNA - tongue [nTPM]":"127.0","Tissue RNA - tonsil [nTPM]":"21.8","Tissue RNA - urinary bladder [nTPM]":"208.9","Tissue RNA - vagina [nTPM]":"157.4","Tissue RNA - white matter [nTPM]":"216.7","Cell RNA - A-431 [nTPM]":"7.0","Cell RNA - A549 [nTPM]":"44.1","Cell RNA - AF22 [nTPM]":"61.9","Cell RNA - AN3-CA [nTPM]":"62.2","Cell RNA - ASC diff [nTPM]":"383.5","Cell RNA - ASC TERT1 [nTPM]":"167.1","Cell RNA - BEWO [nTPM]":"12.6","Cell RNA - BJ [nTPM]":"60.5","Cell RNA - BJ hTERT+ [nTPM]":"68.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"58.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"38.0","Cell RNA - CACO-2 [nTPM]":"48.7","Cell RNA - CAPAN-2 [nTPM]":"1.1","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"7.0","Cell RNA - fHDF\/TERT166 [nTPM]":"172.3","Cell RNA - GAMG [nTPM]":"22.7","Cell RNA - HaCaT [nTPM]":"0.7","Cell RNA - HAP1 [nTPM]":"74.0","Cell RNA - HBEC3-KT [nTPM]":"1.1","Cell RNA - HBF TERT88 [nTPM]":"15.4","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"13.9","Cell RNA - HEL [nTPM]":"4.3","Cell RNA - HeLa [nTPM]":"76.7","Cell RNA - Hep G2 [nTPM]":"17.2","Cell RNA - HHSteC [nTPM]":"201.8","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"263.7","Cell RNA - HSkMC [nTPM]":"126.9","Cell RNA - hTCEpi [nTPM]":"1.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.6","Cell RNA - hTERT-HME1 [nTPM]":"1.8","Cell RNA - hTERT-RPE1 [nTPM]":"72.1","Cell RNA - HUVEC TERT2 [nTPM]":"66.1","Cell RNA - JURKAT [nTPM]":"2.8","Cell RNA - K-562 [nTPM]":"24.5","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"33.2","Cell RNA - MCF7 [nTPM]":"6.1","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"2.0","Cell RNA - NTERA-2 [nTPM]":"3.5","Cell RNA - OE19 [nTPM]":"4.0","Cell RNA - PC-3 [nTPM]":"74.7","Cell RNA - REH [nTPM]":"22.0","Cell RNA - RH-30 [nTPM]":"39.3","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"44.6","Cell RNA - RT4 [nTPM]":"4.8","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"40.6","Cell RNA - SiHa [nTPM]":"16.6","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"134.2","Cell RNA - SuSa [nTPM]":"333.9","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"81.4","Cell RNA - U-138 MG [nTPM]":"12.7","Cell RNA - U-2 OS [nTPM]":"45.7","Cell RNA - U-2197 [nTPM]":"216.9","Cell RNA - U-251 MG [nTPM]":"62.0","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"84.7","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"448.8","Blood RNA - basophil [nTPM]":"32.2","Blood RNA - classical monocyte [nTPM]":"1.4","Blood RNA - eosinophil [nTPM]":"43.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"7.6","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"23.8","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"113.6","Brain RNA - basal ganglia [nTPM]":"161.0","Brain RNA - cerebellum [nTPM]":"153.2","Brain RNA - cerebral cortex [nTPM]":"140.7","Brain RNA - hippocampal formation [nTPM]":"113.5","Brain RNA - hypothalamus [nTPM]":"129.0","Brain RNA - medulla oblongata [nTPM]":"163.3","Brain RNA - midbrain [nTPM]":"144.2","Brain RNA - pons [nTPM]":"159.9","Brain RNA - spinal cord [nTPM]":"135.0","Brain RNA - thalamus [nTPM]":"141.1","Brain RNA - white matter [nTPM]":"216.7","Single Cell Type RNA - Adipocytes [nTPM]":"86.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.5","Single Cell Type RNA - Astrocytes [nTPM]":"50.9","Single Cell Type RNA - B-cells [nTPM]":"2.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"90.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"43.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"82.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"68.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"7.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.8","Single Cell Type RNA - dendritic cells [nTPM]":"2.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.5","Single Cell Type RNA - Early spermatids [nTPM]":"17.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"118.6","Single Cell Type RNA - Endothelial cells [nTPM]":"148.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"10.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"23.1","Single Cell Type RNA - Fibroblasts [nTPM]":"404.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.0","Single Cell Type RNA - granulocytes [nTPM]":"119.7","Single Cell Type RNA - Granulosa cells [nTPM]":"25.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"88.5","Single Cell Type RNA - Hepatocytes [nTPM]":"0.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"558.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"23.4","Single Cell Type RNA - Langerhans cells [nTPM]":"116.8","Single Cell Type RNA - Late spermatids [nTPM]":"11.0","Single Cell Type RNA - Leydig cells [nTPM]":"324.3","Single Cell Type RNA - Macrophages [nTPM]":"93.0","Single Cell Type RNA - Melanocytes [nTPM]":"343.3","Single Cell Type RNA - Microglial cells [nTPM]":"29.0","Single Cell Type RNA - monocytes [nTPM]":"11.8","Single Cell Type RNA - Muller glia cells [nTPM]":"61.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"46.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"217.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.7","Single Cell Type RNA - Paneth cells [nTPM]":"25.2","Single Cell Type RNA - Peritubular cells [nTPM]":"246.4","Single Cell Type RNA - Plasma cells [nTPM]":"1.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"580.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.2","Single Cell Type RNA - Sertoli cells [nTPM]":"230.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"288.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"141.1","Single Cell Type RNA - Spermatocytes [nTPM]":"3.0","Single Cell Type RNA - Spermatogonia [nTPM]":"4.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"103.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"19.0","Single Cell Type RNA - T-cells [nTPM]":"8.7","Single Cell Type RNA - Theca cells [nTPM]":"49.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.9","Single Cell Type RNA - Urothelial cells [nTPM]":"5.2"},{"Gene":"PMPCA","Gene synonym":["Alpha-MPP","CLA1","INPP5E","KIAA0123","SCAR2"],"Ensembl":"ENSG00000165688","Gene description":"Peptidase, mitochondrial processing subunit alpha","Uniprot":["Q10713"],"Chromosome":"9","Position":"136410641-136423761","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Mental retardation","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021648","HPA063735"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA021648":"AB_1855491","HPA063735":"AB_2685108"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.00e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.14e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Tissue RNA - adipose tissue [nTPM]":"29.2","Tissue RNA - adrenal gland [nTPM]":"58.1","Tissue RNA - amygdala [nTPM]":"27.0","Tissue RNA - appendix [nTPM]":"20.6","Tissue RNA - basal ganglia [nTPM]":"27.6","Tissue RNA - bone marrow [nTPM]":"31.4","Tissue RNA - breast [nTPM]":"27.1","Tissue RNA - cerebellum [nTPM]":"27.0","Tissue RNA - cerebral cortex [nTPM]":"34.6","Tissue RNA - cervix [nTPM]":"29.2","Tissue RNA - choroid plexus [nTPM]":"36.8","Tissue RNA - colon [nTPM]":"32.2","Tissue RNA - duodenum [nTPM]":"24.8","Tissue RNA - endometrium 1 [nTPM]":"26.8","Tissue RNA - epididymis [nTPM]":"10.4","Tissue RNA - esophagus [nTPM]":"34.5","Tissue RNA - fallopian tube [nTPM]":"27.5","Tissue RNA - gallbladder [nTPM]":"17.9","Tissue RNA - heart muscle [nTPM]":"73.2","Tissue RNA - hippocampal formation [nTPM]":"28.0","Tissue RNA - hypothalamus [nTPM]":"27.3","Tissue RNA - kidney [nTPM]":"37.3","Tissue RNA - liver [nTPM]":"110.8","Tissue RNA - lung [nTPM]":"25.4","Tissue RNA - lymph node [nTPM]":"27.1","Tissue RNA - medulla oblongata [nTPM]":"27.1","Tissue RNA - midbrain [nTPM]":"27.6","Tissue RNA - ovary [nTPM]":"29.3","Tissue RNA - pancreas [nTPM]":"28.8","Tissue RNA - parathyroid gland [nTPM]":"26.9","Tissue RNA - pituitary gland [nTPM]":"38.8","Tissue RNA - placenta [nTPM]":"20.8","Tissue RNA - pons [nTPM]":"27.9","Tissue RNA - prostate [nTPM]":"31.8","Tissue RNA - rectum [nTPM]":"15.3","Tissue RNA - retina [nTPM]":"8.8","Tissue RNA - salivary gland [nTPM]":"28.4","Tissue RNA - seminal vesicle [nTPM]":"16.1","Tissue RNA - skeletal muscle [nTPM]":"69.2","Tissue RNA - skin 1 [nTPM]":"37.6","Tissue RNA - small intestine [nTPM]":"30.6","Tissue RNA - smooth muscle [nTPM]":"15.3","Tissue RNA - spinal cord [nTPM]":"25.6","Tissue RNA - spleen [nTPM]":"38.2","Tissue RNA - stomach 1 [nTPM]":"35.3","Tissue RNA - testis [nTPM]":"37.8","Tissue RNA - thalamus [nTPM]":"27.9","Tissue RNA - thymus [nTPM]":"21.4","Tissue RNA - thyroid gland [nTPM]":"29.4","Tissue RNA - tongue [nTPM]":"50.0","Tissue RNA - tonsil [nTPM]":"17.0","Tissue RNA - urinary bladder [nTPM]":"28.0","Tissue RNA - vagina [nTPM]":"27.8","Tissue RNA - white matter [nTPM]":"26.7","Cell RNA - A-431 [nTPM]":"48.7","Cell RNA - A549 [nTPM]":"87.7","Cell RNA - AF22 [nTPM]":"41.8","Cell RNA - AN3-CA [nTPM]":"84.5","Cell RNA - ASC diff [nTPM]":"30.8","Cell RNA - ASC TERT1 [nTPM]":"45.0","Cell RNA - BEWO [nTPM]":"63.2","Cell RNA - BJ [nTPM]":"49.3","Cell RNA - BJ hTERT+ [nTPM]":"39.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"67.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"48.9","Cell RNA - CACO-2 [nTPM]":"101.1","Cell RNA - CAPAN-2 [nTPM]":"56.5","Cell RNA - Daudi [nTPM]":"67.4","Cell RNA - EFO-21 [nTPM]":"50.5","Cell RNA - fHDF\/TERT166 [nTPM]":"50.3","Cell RNA - GAMG [nTPM]":"36.2","Cell RNA - HaCaT [nTPM]":"110.2","Cell RNA - HAP1 [nTPM]":"77.9","Cell RNA - HBEC3-KT [nTPM]":"72.0","Cell RNA - HBF TERT88 [nTPM]":"30.0","Cell RNA - HDLM-2 [nTPM]":"97.2","Cell RNA - HEK 293 [nTPM]":"92.8","Cell RNA - HEL [nTPM]":"54.6","Cell RNA - HeLa [nTPM]":"113.2","Cell RNA - Hep G2 [nTPM]":"123.6","Cell RNA - HHSteC [nTPM]":"53.9","Cell RNA - HL-60 [nTPM]":"71.7","Cell RNA - HMC-1 [nTPM]":"44.9","Cell RNA - HSkMC [nTPM]":"66.3","Cell RNA - hTCEpi [nTPM]":"48.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"52.6","Cell RNA - hTERT-HME1 [nTPM]":"27.0","Cell RNA - hTERT-RPE1 [nTPM]":"38.2","Cell RNA - HUVEC TERT2 [nTPM]":"58.0","Cell RNA - JURKAT [nTPM]":"61.2","Cell RNA - K-562 [nTPM]":"140.2","Cell RNA - Karpas-707 [nTPM]":"43.4","Cell RNA - LHCN-M2 [nTPM]":"42.6","Cell RNA - MCF7 [nTPM]":"132.1","Cell RNA - MOLT-4 [nTPM]":"68.1","Cell RNA - NB-4 [nTPM]":"90.1","Cell RNA - NTERA-2 [nTPM]":"85.4","Cell RNA - OE19 [nTPM]":"86.2","Cell RNA - PC-3 [nTPM]":"82.2","Cell RNA - REH [nTPM]":"83.0","Cell RNA - RH-30 [nTPM]":"59.1","Cell RNA - RPMI-8226 [nTPM]":"149.9","Cell RNA - RPTEC TERT1 [nTPM]":"46.3","Cell RNA - RT4 [nTPM]":"33.9","Cell RNA - SCLC-21H [nTPM]":"85.4","Cell RNA - SH-SY5Y [nTPM]":"56.1","Cell RNA - SiHa [nTPM]":"66.6","Cell RNA - SK-BR-3 [nTPM]":"92.9","Cell RNA - SK-MEL-30 [nTPM]":"58.6","Cell RNA - SuSa [nTPM]":"28.6","Cell RNA - T-47d [nTPM]":"127.6","Cell RNA - THP-1 [nTPM]":"95.5","Cell RNA - TIME [nTPM]":"48.2","Cell RNA - U-138 MG [nTPM]":"47.8","Cell RNA - U-2 OS [nTPM]":"50.7","Cell RNA - U-2197 [nTPM]":"39.8","Cell RNA - U-251 MG [nTPM]":"63.8","Cell RNA - U-266\/70 [nTPM]":"26.2","Cell RNA - U-266\/84 [nTPM]":"37.4","Cell RNA - U-698 [nTPM]":"73.5","Cell RNA - U-87 MG [nTPM]":"62.9","Cell RNA - U-937 [nTPM]":"61.3","Cell RNA - WM-115 [nTPM]":"43.9","Blood RNA - basophil [nTPM]":"37.4","Blood RNA - classical monocyte [nTPM]":"50.5","Blood RNA - eosinophil [nTPM]":"36.5","Blood RNA - gdT-cell [nTPM]":"53.2","Blood RNA - intermediate monocyte [nTPM]":"51.9","Blood RNA - MAIT T-cell [nTPM]":"51.4","Blood RNA - memory B-cell [nTPM]":"52.5","Blood RNA - memory CD4 T-cell [nTPM]":"49.0","Blood RNA - memory CD8 T-cell [nTPM]":"57.2","Blood RNA - myeloid DC [nTPM]":"61.7","Blood RNA - naive B-cell [nTPM]":"48.8","Blood RNA - naive CD4 T-cell [nTPM]":"57.9","Blood RNA - naive CD8 T-cell [nTPM]":"50.2","Blood RNA - neutrophil [nTPM]":"11.9","Blood RNA - NK-cell [nTPM]":"67.2","Blood RNA - non-classical monocyte [nTPM]":"51.5","Blood RNA - plasmacytoid DC [nTPM]":"31.4","Blood RNA - T-reg [nTPM]":"52.7","Blood RNA - total PBMC [nTPM]":"62.2","Brain RNA - amygdala [nTPM]":"27.0","Brain RNA - basal ganglia [nTPM]":"27.6","Brain RNA - cerebellum [nTPM]":"27.0","Brain RNA - cerebral cortex [nTPM]":"34.6","Brain RNA - hippocampal formation [nTPM]":"28.0","Brain RNA - hypothalamus [nTPM]":"27.3","Brain RNA - medulla oblongata [nTPM]":"27.1","Brain RNA - midbrain [nTPM]":"27.6","Brain RNA - pons [nTPM]":"27.9","Brain RNA - spinal cord [nTPM]":"25.6","Brain RNA - thalamus [nTPM]":"27.9","Brain RNA - white matter [nTPM]":"26.7","Single Cell Type RNA - Adipocytes [nTPM]":"17.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.7","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"24.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"27.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"40.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"65.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"27.9","Single Cell Type RNA - Bipolar cells [nTPM]":"24.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"35.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"32.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"103.1","Single Cell Type RNA - dendritic cells [nTPM]":"22.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"28.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"49.0","Single Cell Type RNA - Ductal cells [nTPM]":"32.9","Single Cell Type RNA - Early spermatids [nTPM]":"24.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.5","Single Cell Type RNA - Endothelial cells [nTPM]":"21.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.8","Single Cell Type RNA - Erythroid cells [nTPM]":"23.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"50.4","Single Cell Type RNA - Fibroblasts [nTPM]":"23.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.2","Single Cell Type RNA - granulocytes [nTPM]":"24.7","Single Cell Type RNA - Granulosa cells [nTPM]":"44.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.6","Single Cell Type RNA - Hepatocytes [nTPM]":"57.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"37.8","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.2","Single Cell Type RNA - Ionocytes [nTPM]":"44.7","Single Cell Type RNA - Kupffer cells [nTPM]":"19.2","Single Cell Type RNA - Langerhans cells [nTPM]":"14.6","Single Cell Type RNA - Late spermatids [nTPM]":"15.8","Single Cell Type RNA - Leydig cells [nTPM]":"19.0","Single Cell Type RNA - Macrophages [nTPM]":"17.4","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"21.0","Single Cell Type RNA - Muller glia cells [nTPM]":"22.9","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"31.6","Single Cell Type RNA - Paneth cells [nTPM]":"20.9","Single Cell Type RNA - Peritubular cells [nTPM]":"22.6","Single Cell Type RNA - Plasma cells [nTPM]":"26.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"22.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"25.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"46.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"27.4","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.9","Single Cell Type RNA - Spermatocytes [nTPM]":"37.7","Single Cell Type RNA - Spermatogonia [nTPM]":"42.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"26.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"103.8","Single Cell Type RNA - T-cells [nTPM]":"21.7","Single Cell Type RNA - Theca cells [nTPM]":"77.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"38.6","Single Cell Type RNA - Urothelial cells [nTPM]":"28.5"},{"Gene":"PMPCB","Gene synonym":["MPPB","MPPP52"],"Ensembl":"ENSG00000105819","Gene description":"Peptidase, mitochondrial processing subunit beta","Uniprot":["O75439"],"Chromosome":"7","Position":"103297435-103329511","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040674","HPA074168"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"19000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA040674":"AB_10961998","HPA074168":"AB_2686671"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.79e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.18e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.95e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Tissue RNA - adipose tissue [nTPM]":"30.8","Tissue RNA - adrenal gland [nTPM]":"42.0","Tissue RNA - amygdala [nTPM]":"16.9","Tissue RNA - appendix [nTPM]":"22.3","Tissue RNA - basal ganglia [nTPM]":"18.2","Tissue RNA - bone marrow [nTPM]":"53.5","Tissue RNA - breast [nTPM]":"32.5","Tissue RNA - cerebellum [nTPM]":"18.9","Tissue RNA - cerebral cortex [nTPM]":"22.1","Tissue RNA - cervix [nTPM]":"33.3","Tissue RNA - choroid plexus [nTPM]":"24.7","Tissue RNA - colon [nTPM]":"33.4","Tissue RNA - duodenum [nTPM]":"38.0","Tissue RNA - endometrium 1 [nTPM]":"29.9","Tissue RNA - epididymis [nTPM]":"26.2","Tissue RNA - esophagus [nTPM]":"27.7","Tissue RNA - fallopian tube [nTPM]":"29.3","Tissue RNA - gallbladder [nTPM]":"25.1","Tissue RNA - heart muscle [nTPM]":"44.9","Tissue RNA - hippocampal formation [nTPM]":"18.8","Tissue RNA - hypothalamus [nTPM]":"18.1","Tissue RNA - kidney [nTPM]":"47.4","Tissue RNA - liver [nTPM]":"46.1","Tissue RNA - lung [nTPM]":"22.6","Tissue RNA - lymph node [nTPM]":"36.4","Tissue RNA - medulla oblongata [nTPM]":"16.5","Tissue RNA - midbrain [nTPM]":"16.6","Tissue RNA - ovary [nTPM]":"35.4","Tissue RNA - pancreas [nTPM]":"41.1","Tissue RNA - parathyroid gland [nTPM]":"39.7","Tissue RNA - pituitary gland [nTPM]":"22.4","Tissue RNA - placenta [nTPM]":"25.8","Tissue RNA - pons [nTPM]":"17.6","Tissue RNA - prostate [nTPM]":"31.5","Tissue RNA - rectum [nTPM]":"33.2","Tissue RNA - retina [nTPM]":"25.4","Tissue RNA - salivary gland [nTPM]":"30.6","Tissue RNA - seminal vesicle [nTPM]":"28.1","Tissue RNA - skeletal muscle [nTPM]":"34.8","Tissue RNA - skin 1 [nTPM]":"33.2","Tissue RNA - small intestine [nTPM]":"32.4","Tissue RNA - smooth muscle [nTPM]":"26.3","Tissue RNA - spinal cord [nTPM]":"17.2","Tissue RNA - spleen [nTPM]":"28.2","Tissue RNA - stomach 1 [nTPM]":"35.8","Tissue RNA - testis [nTPM]":"26.7","Tissue RNA - thalamus [nTPM]":"17.4","Tissue RNA - thymus [nTPM]":"30.2","Tissue RNA - thyroid gland [nTPM]":"33.4","Tissue RNA - tongue [nTPM]":"38.2","Tissue RNA - tonsil [nTPM]":"33.9","Tissue RNA - urinary bladder [nTPM]":"29.3","Tissue RNA - vagina [nTPM]":"28.4","Tissue RNA - white matter [nTPM]":"19.9","Cell RNA - A-431 [nTPM]":"30.2","Cell RNA - A549 [nTPM]":"42.8","Cell RNA - AF22 [nTPM]":"49.9","Cell RNA - AN3-CA [nTPM]":"69.4","Cell RNA - ASC diff [nTPM]":"28.5","Cell RNA - ASC TERT1 [nTPM]":"57.1","Cell RNA - BEWO [nTPM]":"38.0","Cell RNA - BJ [nTPM]":"26.7","Cell RNA - BJ hTERT+ [nTPM]":"45.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"54.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"62.8","Cell RNA - CACO-2 [nTPM]":"47.7","Cell RNA - CAPAN-2 [nTPM]":"33.7","Cell RNA - Daudi [nTPM]":"76.9","Cell RNA - EFO-21 [nTPM]":"41.7","Cell RNA - fHDF\/TERT166 [nTPM]":"47.9","Cell RNA - GAMG [nTPM]":"58.0","Cell RNA - HaCaT [nTPM]":"37.5","Cell RNA - HAP1 [nTPM]":"59.7","Cell RNA - HBEC3-KT [nTPM]":"43.2","Cell RNA - HBF TERT88 [nTPM]":"49.2","Cell RNA - HDLM-2 [nTPM]":"26.4","Cell RNA - HEK 293 [nTPM]":"69.4","Cell RNA - HEL [nTPM]":"26.4","Cell RNA - HeLa [nTPM]":"74.0","Cell RNA - Hep G2 [nTPM]":"61.6","Cell RNA - HHSteC [nTPM]":"35.0","Cell RNA - HL-60 [nTPM]":"35.0","Cell RNA - HMC-1 [nTPM]":"30.6","Cell RNA - HSkMC [nTPM]":"53.4","Cell RNA - hTCEpi [nTPM]":"40.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"41.8","Cell RNA - hTERT-HME1 [nTPM]":"39.6","Cell RNA - hTERT-RPE1 [nTPM]":"51.3","Cell RNA - HUVEC TERT2 [nTPM]":"28.8","Cell RNA - JURKAT [nTPM]":"55.9","Cell RNA - K-562 [nTPM]":"52.5","Cell RNA - Karpas-707 [nTPM]":"77.9","Cell RNA - LHCN-M2 [nTPM]":"48.5","Cell RNA - MCF7 [nTPM]":"71.1","Cell RNA - MOLT-4 [nTPM]":"59.2","Cell RNA - NB-4 [nTPM]":"82.0","Cell RNA - NTERA-2 [nTPM]":"59.2","Cell RNA - OE19 [nTPM]":"60.4","Cell RNA - PC-3 [nTPM]":"52.4","Cell RNA - REH [nTPM]":"42.7","Cell RNA - RH-30 [nTPM]":"34.3","Cell RNA - RPMI-8226 [nTPM]":"79.4","Cell RNA - RPTEC TERT1 [nTPM]":"50.3","Cell RNA - RT4 [nTPM]":"54.2","Cell RNA - SCLC-21H [nTPM]":"62.2","Cell RNA - SH-SY5Y [nTPM]":"76.5","Cell RNA - SiHa [nTPM]":"37.3","Cell RNA - SK-BR-3 [nTPM]":"108.6","Cell RNA - SK-MEL-30 [nTPM]":"55.8","Cell RNA - SuSa [nTPM]":"49.5","Cell RNA - T-47d [nTPM]":"45.3","Cell RNA - THP-1 [nTPM]":"49.1","Cell RNA - TIME [nTPM]":"24.9","Cell RNA - U-138 MG [nTPM]":"48.3","Cell RNA - U-2 OS [nTPM]":"57.9","Cell RNA - U-2197 [nTPM]":"85.1","Cell RNA - U-251 MG [nTPM]":"52.3","Cell RNA - U-266\/70 [nTPM]":"57.4","Cell RNA - U-266\/84 [nTPM]":"79.9","Cell RNA - U-698 [nTPM]":"61.8","Cell RNA - U-87 MG [nTPM]":"35.7","Cell RNA - U-937 [nTPM]":"59.3","Cell RNA - WM-115 [nTPM]":"38.2","Blood RNA - basophil [nTPM]":"16.7","Blood RNA - classical monocyte [nTPM]":"19.3","Blood RNA - eosinophil [nTPM]":"13.2","Blood RNA - gdT-cell [nTPM]":"18.3","Blood RNA - intermediate monocyte [nTPM]":"21.4","Blood RNA - MAIT T-cell [nTPM]":"20.1","Blood RNA - memory B-cell [nTPM]":"25.9","Blood RNA - memory CD4 T-cell [nTPM]":"21.1","Blood RNA - memory CD8 T-cell [nTPM]":"18.5","Blood RNA - myeloid DC [nTPM]":"24.7","Blood RNA - naive B-cell [nTPM]":"19.3","Blood RNA - naive CD4 T-cell [nTPM]":"26.1","Blood RNA - naive CD8 T-cell [nTPM]":"21.7","Blood RNA - neutrophil [nTPM]":"5.7","Blood RNA - NK-cell [nTPM]":"17.9","Blood RNA - non-classical monocyte [nTPM]":"19.7","Blood RNA - plasmacytoid DC [nTPM]":"12.6","Blood RNA - T-reg [nTPM]":"30.2","Blood RNA - total PBMC [nTPM]":"22.3","Brain RNA - amygdala [nTPM]":"16.9","Brain RNA - basal ganglia [nTPM]":"18.2","Brain RNA - cerebellum [nTPM]":"18.9","Brain RNA - cerebral cortex [nTPM]":"22.1","Brain RNA - hippocampal formation [nTPM]":"18.8","Brain RNA - hypothalamus [nTPM]":"18.1","Brain RNA - medulla oblongata [nTPM]":"16.5","Brain RNA - midbrain [nTPM]":"16.6","Brain RNA - pons [nTPM]":"17.6","Brain RNA - spinal cord [nTPM]":"17.2","Brain RNA - thalamus [nTPM]":"17.4","Brain RNA - white matter [nTPM]":"19.9","Single Cell Type RNA - Adipocytes [nTPM]":"32.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"36.9","Single Cell Type RNA - Astrocytes [nTPM]":"27.1","Single Cell Type RNA - B-cells [nTPM]":"54.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"36.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"68.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"123.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"51.8","Single Cell Type RNA - Bipolar cells [nTPM]":"31.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"41.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"37.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"70.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"41.5","Single Cell Type RNA - Club cells [nTPM]":"70.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"125.6","Single Cell Type RNA - dendritic cells [nTPM]":"55.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"35.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"72.4","Single Cell Type RNA - Ductal cells [nTPM]":"75.6","Single Cell Type RNA - Early spermatids [nTPM]":"106.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"38.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"37.0","Single Cell Type RNA - Endothelial cells [nTPM]":"37.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"27.1","Single Cell Type RNA - Erythroid cells [nTPM]":"65.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"36.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"73.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"61.3","Single Cell Type RNA - Fibroblasts [nTPM]":"42.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"35.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"35.0","Single Cell Type RNA - granulocytes [nTPM]":"60.2","Single Cell Type RNA - Granulosa cells [nTPM]":"49.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"31.1","Single Cell Type RNA - Hepatocytes [nTPM]":"53.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"54.6","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"33.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"48.1","Single Cell Type RNA - Ionocytes [nTPM]":"75.3","Single Cell Type RNA - Kupffer cells [nTPM]":"49.4","Single Cell Type RNA - Langerhans cells [nTPM]":"30.7","Single Cell Type RNA - Late spermatids [nTPM]":"24.0","Single Cell Type RNA - Leydig cells [nTPM]":"51.9","Single Cell Type RNA - Macrophages [nTPM]":"42.4","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"92.5","Single Cell Type RNA - Muller glia cells [nTPM]":"35.8","Single Cell Type RNA - NK-cells [nTPM]":"58.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"35.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"44.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"59.7","Single Cell Type RNA - Paneth cells [nTPM]":"45.4","Single Cell Type RNA - Peritubular cells [nTPM]":"49.7","Single Cell Type RNA - Plasma cells [nTPM]":"56.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"35.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"60.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"127.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"58.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"37.9","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"48.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"73.5","Single Cell Type RNA - Spermatocytes [nTPM]":"125.4","Single Cell Type RNA - Spermatogonia [nTPM]":"56.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"47.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"37.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"124.9","Single Cell Type RNA - T-cells [nTPM]":"55.9","Single Cell Type RNA - Theca cells [nTPM]":"63.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"59.1","Single Cell Type RNA - Urothelial cells [nTPM]":"62.2"},{"Gene":"PMVK","Gene synonym":["HUMPMKI","PMK","PMKA"],"Ensembl":"ENSG00000163344","Gene description":"Phosphomevalonate kinase","Uniprot":["Q15126"],"Chromosome":"1","Position":"154924740-154936719","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"266.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029900"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"15000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029900":"AB_10601390"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.70e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.96e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Tissue RNA - adipose tissue [nTPM]":"39.9","Tissue RNA - adrenal gland [nTPM]":"56.4","Tissue RNA - amygdala [nTPM]":"99.0","Tissue RNA - appendix [nTPM]":"29.8","Tissue RNA - basal ganglia [nTPM]":"100.1","Tissue RNA - bone marrow [nTPM]":"15.3","Tissue RNA - breast [nTPM]":"35.0","Tissue RNA - cerebellum [nTPM]":"97.9","Tissue RNA - cerebral cortex [nTPM]":"108.9","Tissue RNA - cervix [nTPM]":"33.4","Tissue RNA - choroid plexus [nTPM]":"95.0","Tissue RNA - colon [nTPM]":"39.9","Tissue RNA - duodenum [nTPM]":"45.9","Tissue RNA - endometrium 1 [nTPM]":"25.9","Tissue RNA - epididymis [nTPM]":"17.7","Tissue RNA - esophagus [nTPM]":"77.7","Tissue RNA - fallopian tube [nTPM]":"37.2","Tissue RNA - gallbladder [nTPM]":"17.2","Tissue RNA - heart muscle [nTPM]":"63.1","Tissue RNA - hippocampal formation [nTPM]":"93.9","Tissue RNA - hypothalamus [nTPM]":"96.4","Tissue RNA - kidney [nTPM]":"53.8","Tissue RNA - liver [nTPM]":"91.9","Tissue RNA - lung [nTPM]":"30.1","Tissue RNA - lymph node [nTPM]":"34.6","Tissue RNA - medulla oblongata [nTPM]":"98.6","Tissue RNA - midbrain [nTPM]":"97.4","Tissue RNA - ovary [nTPM]":"35.8","Tissue RNA - pancreas [nTPM]":"41.6","Tissue RNA - parathyroid gland [nTPM]":"58.2","Tissue RNA - pituitary gland [nTPM]":"60.3","Tissue RNA - placenta [nTPM]":"23.7","Tissue RNA - pons [nTPM]":"96.0","Tissue RNA - prostate [nTPM]":"32.4","Tissue RNA - rectum [nTPM]":"22.2","Tissue RNA - retina [nTPM]":"19.8","Tissue RNA - salivary gland [nTPM]":"34.0","Tissue RNA - seminal vesicle [nTPM]":"27.1","Tissue RNA - skeletal muscle [nTPM]":"79.1","Tissue RNA - skin 1 [nTPM]":"69.2","Tissue RNA - small intestine [nTPM]":"44.2","Tissue RNA - smooth muscle [nTPM]":"27.7","Tissue RNA - spinal cord [nTPM]":"96.4","Tissue RNA - spleen [nTPM]":"45.7","Tissue RNA - stomach 1 [nTPM]":"40.5","Tissue RNA - testis [nTPM]":"26.6","Tissue RNA - thalamus [nTPM]":"102.3","Tissue RNA - thymus [nTPM]":"27.9","Tissue RNA - thyroid gland [nTPM]":"31.5","Tissue RNA - tongue [nTPM]":"47.4","Tissue RNA - tonsil [nTPM]":"36.8","Tissue RNA - urinary bladder [nTPM]":"31.9","Tissue RNA - vagina [nTPM]":"37.9","Tissue RNA - white matter [nTPM]":"99.8","Cell RNA - A-431 [nTPM]":"51.8","Cell RNA - A549 [nTPM]":"72.9","Cell RNA - AF22 [nTPM]":"46.7","Cell RNA - AN3-CA [nTPM]":"72.5","Cell RNA - ASC diff [nTPM]":"43.6","Cell RNA - ASC TERT1 [nTPM]":"30.9","Cell RNA - BEWO [nTPM]":"48.5","Cell RNA - BJ [nTPM]":"40.5","Cell RNA - BJ hTERT+ [nTPM]":"29.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"38.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"37.0","Cell RNA - CACO-2 [nTPM]":"30.6","Cell RNA - CAPAN-2 [nTPM]":"101.0","Cell RNA - Daudi [nTPM]":"75.1","Cell RNA - EFO-21 [nTPM]":"75.9","Cell RNA - fHDF\/TERT166 [nTPM]":"49.3","Cell RNA - GAMG [nTPM]":"40.5","Cell RNA - HaCaT [nTPM]":"49.4","Cell RNA - HAP1 [nTPM]":"65.3","Cell RNA - HBEC3-KT [nTPM]":"63.9","Cell RNA - HBF TERT88 [nTPM]":"17.8","Cell RNA - HDLM-2 [nTPM]":"103.3","Cell RNA - HEK 293 [nTPM]":"28.9","Cell RNA - HEL [nTPM]":"34.1","Cell RNA - HeLa [nTPM]":"104.1","Cell RNA - Hep G2 [nTPM]":"29.0","Cell RNA - HHSteC [nTPM]":"40.0","Cell RNA - HL-60 [nTPM]":"51.4","Cell RNA - HMC-1 [nTPM]":"29.3","Cell RNA - HSkMC [nTPM]":"36.3","Cell RNA - hTCEpi [nTPM]":"58.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"70.2","Cell RNA - hTERT-HME1 [nTPM]":"49.6","Cell RNA - hTERT-RPE1 [nTPM]":"19.5","Cell RNA - HUVEC TERT2 [nTPM]":"40.0","Cell RNA - JURKAT [nTPM]":"65.9","Cell RNA - K-562 [nTPM]":"36.8","Cell RNA - Karpas-707 [nTPM]":"221.7","Cell RNA - LHCN-M2 [nTPM]":"41.3","Cell RNA - MCF7 [nTPM]":"108.3","Cell RNA - MOLT-4 [nTPM]":"40.8","Cell RNA - NB-4 [nTPM]":"51.0","Cell RNA - NTERA-2 [nTPM]":"41.0","Cell RNA - OE19 [nTPM]":"121.7","Cell RNA - PC-3 [nTPM]":"95.0","Cell RNA - REH [nTPM]":"60.3","Cell RNA - RH-30 [nTPM]":"29.8","Cell RNA - RPMI-8226 [nTPM]":"171.1","Cell RNA - RPTEC TERT1 [nTPM]":"66.1","Cell RNA - RT4 [nTPM]":"38.4","Cell RNA - SCLC-21H [nTPM]":"37.7","Cell RNA - SH-SY5Y [nTPM]":"91.1","Cell RNA - SiHa [nTPM]":"44.1","Cell RNA - SK-BR-3 [nTPM]":"75.7","Cell RNA - SK-MEL-30 [nTPM]":"51.9","Cell RNA - SuSa [nTPM]":"35.0","Cell RNA - T-47d [nTPM]":"146.7","Cell RNA - THP-1 [nTPM]":"91.1","Cell RNA - TIME [nTPM]":"32.7","Cell RNA - U-138 MG [nTPM]":"35.8","Cell RNA - U-2 OS [nTPM]":"29.2","Cell RNA - U-2197 [nTPM]":"84.4","Cell RNA - U-251 MG [nTPM]":"62.1","Cell RNA - U-266\/70 [nTPM]":"174.0","Cell RNA - U-266\/84 [nTPM]":"153.2","Cell RNA - U-698 [nTPM]":"131.8","Cell RNA - U-87 MG [nTPM]":"58.9","Cell RNA - U-937 [nTPM]":"83.9","Cell RNA - WM-115 [nTPM]":"46.7","Blood RNA - basophil [nTPM]":"28.0","Blood RNA - classical monocyte [nTPM]":"80.9","Blood RNA - eosinophil [nTPM]":"91.8","Blood RNA - gdT-cell [nTPM]":"68.2","Blood RNA - intermediate monocyte [nTPM]":"205.6","Blood RNA - MAIT T-cell [nTPM]":"110.1","Blood RNA - memory B-cell [nTPM]":"114.8","Blood RNA - memory CD4 T-cell [nTPM]":"93.1","Blood RNA - memory CD8 T-cell [nTPM]":"70.6","Blood RNA - myeloid DC [nTPM]":"93.6","Blood RNA - naive B-cell [nTPM]":"111.1","Blood RNA - naive CD4 T-cell [nTPM]":"59.1","Blood RNA - naive CD8 T-cell [nTPM]":"59.1","Blood RNA - neutrophil [nTPM]":"6.9","Blood RNA - NK-cell [nTPM]":"59.7","Blood RNA - non-classical monocyte [nTPM]":"219.4","Blood RNA - plasmacytoid DC [nTPM]":"96.5","Blood RNA - T-reg [nTPM]":"134.3","Blood RNA - total PBMC [nTPM]":"80.0","Brain RNA - amygdala [nTPM]":"99.0","Brain RNA - basal ganglia [nTPM]":"100.1","Brain RNA - cerebellum [nTPM]":"97.9","Brain RNA - cerebral cortex [nTPM]":"108.9","Brain RNA - hippocampal formation [nTPM]":"93.9","Brain RNA - hypothalamus [nTPM]":"96.4","Brain RNA - medulla oblongata [nTPM]":"98.6","Brain RNA - midbrain [nTPM]":"97.4","Brain RNA - pons [nTPM]":"96.0","Brain RNA - spinal cord [nTPM]":"96.4","Brain RNA - thalamus [nTPM]":"102.3","Brain RNA - white matter [nTPM]":"99.8","Single Cell Type RNA - Adipocytes [nTPM]":"22.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"57.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"37.5","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"42.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"69.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"105.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"95.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"51.8","Single Cell Type RNA - Bipolar cells [nTPM]":"38.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"67.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"68.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"57.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"78.6","Single Cell Type RNA - Club cells [nTPM]":"42.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"53.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"235.7","Single Cell Type RNA - dendritic cells [nTPM]":"31.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"65.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"266.1","Single Cell Type RNA - Ductal cells [nTPM]":"69.6","Single Cell Type RNA - Early spermatids [nTPM]":"9.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"45.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"28.5","Single Cell Type RNA - Endothelial cells [nTPM]":"29.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"66.4","Single Cell Type RNA - Erythroid cells [nTPM]":"35.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"71.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"108.1","Single Cell Type RNA - Fibroblasts [nTPM]":"45.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"46.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"44.2","Single Cell Type RNA - granulocytes [nTPM]":"22.2","Single Cell Type RNA - Granulosa cells [nTPM]":"49.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"39.3","Single Cell Type RNA - Hepatocytes [nTPM]":"146.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"141.0","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"78.9","Single Cell Type RNA - Ionocytes [nTPM]":"67.1","Single Cell Type RNA - Kupffer cells [nTPM]":"67.9","Single Cell Type RNA - Langerhans cells [nTPM]":"49.5","Single Cell Type RNA - Late spermatids [nTPM]":"13.5","Single Cell Type RNA - Leydig cells [nTPM]":"42.6","Single Cell Type RNA - Macrophages [nTPM]":"47.8","Single Cell Type RNA - Melanocytes [nTPM]":"65.8","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"49.5","Single Cell Type RNA - Muller glia cells [nTPM]":"119.1","Single Cell Type RNA - NK-cells [nTPM]":"41.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"61.7","Single Cell Type RNA - Paneth cells [nTPM]":"61.7","Single Cell Type RNA - Peritubular cells [nTPM]":"47.8","Single Cell Type RNA - Plasma cells [nTPM]":"58.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"53.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"219.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"246.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"27.4","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"46.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"48.4","Single Cell Type RNA - Spermatocytes [nTPM]":"51.3","Single Cell Type RNA - Spermatogonia [nTPM]":"51.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"81.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"90.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"227.7","Single Cell Type RNA - T-cells [nTPM]":"45.1","Single Cell Type RNA - Theca cells [nTPM]":"162.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"79.9","Single Cell Type RNA - Urothelial cells [nTPM]":"76.2"},{"Gene":"PNKP","Gene synonym":["PNK"],"Ensembl":"ENSG00000039650","Gene description":"Polynucleotide kinase 3'-phosphatase","Uniprot":["Q96T60"],"Chromosome":"19","Position":"49859882-49878351","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["Hydrolase","Kinase","Multifunctional enzyme","Transferase"],"Disease involvement":["Disease variant","Epilepsy","Mental retardation","Neurodegeneration","Primary microcephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006782"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA006782":"AB_1855496"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.18e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-3"},"Tissue RNA - adipose tissue [nTPM]":"18.9","Tissue RNA - adrenal gland [nTPM]":"45.1","Tissue RNA - amygdala [nTPM]":"12.0","Tissue RNA - appendix [nTPM]":"21.0","Tissue RNA - basal ganglia [nTPM]":"12.9","Tissue RNA - bone marrow [nTPM]":"26.4","Tissue RNA - breast [nTPM]":"21.2","Tissue RNA - cerebellum [nTPM]":"12.8","Tissue RNA - cerebral cortex [nTPM]":"16.2","Tissue RNA - cervix [nTPM]":"21.1","Tissue RNA - choroid plexus [nTPM]":"24.2","Tissue RNA - colon [nTPM]":"21.6","Tissue RNA - duodenum [nTPM]":"16.0","Tissue RNA - endometrium 1 [nTPM]":"21.3","Tissue RNA - epididymis [nTPM]":"13.5","Tissue RNA - esophagus [nTPM]":"19.4","Tissue RNA - fallopian tube [nTPM]":"22.9","Tissue RNA - gallbladder [nTPM]":"10.6","Tissue RNA - heart muscle [nTPM]":"23.9","Tissue RNA - hippocampal formation [nTPM]":"14.4","Tissue RNA - hypothalamus [nTPM]":"11.9","Tissue RNA - kidney [nTPM]":"27.3","Tissue RNA - liver [nTPM]":"22.4","Tissue RNA - lung [nTPM]":"22.2","Tissue RNA - lymph node [nTPM]":"17.5","Tissue RNA - medulla oblongata [nTPM]":"14.0","Tissue RNA - midbrain [nTPM]":"14.0","Tissue RNA - ovary [nTPM]":"23.7","Tissue RNA - pancreas [nTPM]":"28.6","Tissue RNA - parathyroid gland [nTPM]":"16.7","Tissue RNA - pituitary gland [nTPM]":"36.8","Tissue RNA - placenta [nTPM]":"11.1","Tissue RNA - pons [nTPM]":"14.3","Tissue RNA - prostate [nTPM]":"25.3","Tissue RNA - rectum [nTPM]":"13.1","Tissue RNA - retina [nTPM]":"10.1","Tissue RNA - salivary gland [nTPM]":"21.6","Tissue RNA - seminal vesicle [nTPM]":"12.4","Tissue RNA - skeletal muscle [nTPM]":"18.5","Tissue RNA - skin 1 [nTPM]":"17.8","Tissue RNA - small intestine [nTPM]":"22.8","Tissue RNA - smooth muscle [nTPM]":"11.5","Tissue RNA - spinal cord [nTPM]":"12.8","Tissue RNA - spleen [nTPM]":"37.2","Tissue RNA - stomach 1 [nTPM]":"25.0","Tissue RNA - testis [nTPM]":"21.2","Tissue RNA - thalamus [nTPM]":"13.3","Tissue RNA - thymus [nTPM]":"12.3","Tissue RNA - thyroid gland [nTPM]":"31.9","Tissue RNA - tongue [nTPM]":"7.8","Tissue RNA - tonsil [nTPM]":"15.3","Tissue RNA - urinary bladder [nTPM]":"19.4","Tissue RNA - vagina [nTPM]":"18.0","Tissue RNA - white matter [nTPM]":"14.1","Cell RNA - A-431 [nTPM]":"27.5","Cell RNA - A549 [nTPM]":"17.4","Cell RNA - AF22 [nTPM]":"19.1","Cell RNA - AN3-CA [nTPM]":"27.2","Cell RNA - ASC diff [nTPM]":"15.8","Cell RNA - ASC TERT1 [nTPM]":"13.4","Cell RNA - BEWO [nTPM]":"28.6","Cell RNA - BJ [nTPM]":"43.4","Cell RNA - BJ hTERT+ [nTPM]":"21.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.7","Cell RNA - CACO-2 [nTPM]":"17.5","Cell RNA - CAPAN-2 [nTPM]":"34.2","Cell RNA - Daudi [nTPM]":"18.4","Cell RNA - EFO-21 [nTPM]":"13.6","Cell RNA - fHDF\/TERT166 [nTPM]":"13.6","Cell RNA - GAMG [nTPM]":"11.3","Cell RNA - HaCaT [nTPM]":"23.5","Cell RNA - HAP1 [nTPM]":"6.1","Cell RNA - HBEC3-KT [nTPM]":"25.9","Cell RNA - HBF TERT88 [nTPM]":"10.9","Cell RNA - HDLM-2 [nTPM]":"22.3","Cell RNA - HEK 293 [nTPM]":"27.2","Cell RNA - HEL [nTPM]":"30.0","Cell RNA - HeLa [nTPM]":"36.7","Cell RNA - Hep G2 [nTPM]":"14.8","Cell RNA - HHSteC [nTPM]":"12.2","Cell RNA - HL-60 [nTPM]":"25.8","Cell RNA - HMC-1 [nTPM]":"36.3","Cell RNA - HSkMC [nTPM]":"13.2","Cell RNA - hTCEpi [nTPM]":"13.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"17.9","Cell RNA - hTERT-HME1 [nTPM]":"11.0","Cell RNA - hTERT-RPE1 [nTPM]":"16.9","Cell RNA - HUVEC TERT2 [nTPM]":"26.3","Cell RNA - JURKAT [nTPM]":"23.4","Cell RNA - K-562 [nTPM]":"14.9","Cell RNA - Karpas-707 [nTPM]":"34.3","Cell RNA - LHCN-M2 [nTPM]":"24.7","Cell RNA - MCF7 [nTPM]":"18.8","Cell RNA - MOLT-4 [nTPM]":"28.7","Cell RNA - NB-4 [nTPM]":"23.5","Cell RNA - NTERA-2 [nTPM]":"16.0","Cell RNA - OE19 [nTPM]":"28.3","Cell RNA - PC-3 [nTPM]":"37.4","Cell RNA - REH [nTPM]":"24.3","Cell RNA - RH-30 [nTPM]":"15.9","Cell RNA - RPMI-8226 [nTPM]":"34.7","Cell RNA - RPTEC TERT1 [nTPM]":"21.0","Cell RNA - RT4 [nTPM]":"68.5","Cell RNA - SCLC-21H [nTPM]":"20.6","Cell RNA - SH-SY5Y [nTPM]":"33.4","Cell RNA - SiHa [nTPM]":"19.3","Cell RNA - SK-BR-3 [nTPM]":"52.5","Cell RNA - SK-MEL-30 [nTPM]":"9.2","Cell RNA - SuSa [nTPM]":"14.5","Cell RNA - T-47d [nTPM]":"10.2","Cell RNA - THP-1 [nTPM]":"14.8","Cell RNA - TIME [nTPM]":"36.0","Cell RNA - U-138 MG [nTPM]":"37.6","Cell RNA - U-2 OS [nTPM]":"24.9","Cell RNA - U-2197 [nTPM]":"9.6","Cell RNA - U-251 MG [nTPM]":"35.8","Cell RNA - U-266\/70 [nTPM]":"38.7","Cell RNA - U-266\/84 [nTPM]":"16.5","Cell RNA - U-698 [nTPM]":"13.0","Cell RNA - U-87 MG [nTPM]":"33.8","Cell RNA - U-937 [nTPM]":"12.3","Cell RNA - WM-115 [nTPM]":"30.8","Blood RNA - basophil [nTPM]":"1.8","Blood RNA - classical monocyte [nTPM]":"12.3","Blood RNA - eosinophil [nTPM]":"16.7","Blood RNA - gdT-cell [nTPM]":"9.2","Blood RNA - intermediate monocyte [nTPM]":"11.5","Blood RNA - MAIT T-cell [nTPM]":"7.9","Blood RNA - memory B-cell [nTPM]":"9.1","Blood RNA - memory CD4 T-cell [nTPM]":"7.8","Blood RNA - memory CD8 T-cell [nTPM]":"7.3","Blood RNA - myeloid DC [nTPM]":"9.8","Blood RNA - naive B-cell [nTPM]":"12.2","Blood RNA - naive CD4 T-cell [nTPM]":"5.7","Blood RNA - naive CD8 T-cell [nTPM]":"5.0","Blood RNA - neutrophil [nTPM]":"23.4","Blood RNA - NK-cell [nTPM]":"3.9","Blood RNA - non-classical monocyte [nTPM]":"18.1","Blood RNA - plasmacytoid DC [nTPM]":"5.5","Blood RNA - T-reg [nTPM]":"9.1","Blood RNA - total PBMC [nTPM]":"5.8","Brain RNA - amygdala [nTPM]":"12.0","Brain RNA - basal ganglia [nTPM]":"12.9","Brain RNA - cerebellum [nTPM]":"12.8","Brain RNA - cerebral cortex [nTPM]":"16.2","Brain RNA - hippocampal formation [nTPM]":"14.4","Brain RNA - hypothalamus [nTPM]":"11.9","Brain RNA - medulla oblongata [nTPM]":"14.0","Brain RNA - midbrain [nTPM]":"14.0","Brain RNA - pons [nTPM]":"14.3","Brain RNA - spinal cord [nTPM]":"12.8","Brain RNA - thalamus [nTPM]":"13.3","Brain RNA - white matter [nTPM]":"14.1","Single Cell Type RNA - Adipocytes [nTPM]":"23.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.6","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"47.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"35.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.6","Single Cell Type RNA - Bipolar cells [nTPM]":"40.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"28.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"19.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"81.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"44.5","Single Cell Type RNA - dendritic cells [nTPM]":"37.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"40.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"42.5","Single Cell Type RNA - Early spermatids [nTPM]":"15.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"28.5","Single Cell Type RNA - Endothelial cells [nTPM]":"26.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"30.5","Single Cell Type RNA - Erythroid cells [nTPM]":"17.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"39.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"35.1","Single Cell Type RNA - Fibroblasts [nTPM]":"19.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"31.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"28.0","Single Cell Type RNA - granulocytes [nTPM]":"29.1","Single Cell Type RNA - Granulosa cells [nTPM]":"54.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"35.0","Single Cell Type RNA - Hepatocytes [nTPM]":"20.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"39.5","Single Cell Type RNA - Horizontal cells [nTPM]":"33.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.7","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"27.7","Single Cell Type RNA - Langerhans cells [nTPM]":"19.0","Single Cell Type RNA - Late spermatids [nTPM]":"32.9","Single Cell Type RNA - Leydig cells [nTPM]":"59.4","Single Cell Type RNA - Macrophages [nTPM]":"26.8","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"46.1","Single Cell Type RNA - Muller glia cells [nTPM]":"18.4","Single Cell Type RNA - NK-cells [nTPM]":"96.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"44.6","Single Cell Type RNA - Paneth cells [nTPM]":"22.3","Single Cell Type RNA - Peritubular cells [nTPM]":"44.8","Single Cell Type RNA - Plasma cells [nTPM]":"40.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"33.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"27.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"36.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"73.9","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.1","Single Cell Type RNA - Spermatocytes [nTPM]":"19.4","Single Cell Type RNA - Spermatogonia [nTPM]":"28.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"49.3","Single Cell Type RNA - T-cells [nTPM]":"39.2","Single Cell Type RNA - Theca cells [nTPM]":"83.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"34.1","Single Cell Type RNA - Urothelial cells [nTPM]":"35.6"},{"Gene":"PNPLA1","Gene synonym":["dJ50J22.1","FLJ38755"],"Ensembl":"ENSG00000180316","Gene description":"Patatin like phospholipase domain containing 1","Uniprot":["Q8N8W4"],"Chromosome":"6","Position":"36243203-36313955","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"skin 1":"23.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"1.9","granulocytes":"4.5","Oligodendrocyte precursor cells":"1.5","Proximal enterocytes":"1.5","Proximal tubular cells":"3.8","Suprabasal keratinocytes":"3.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"1.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"basophil":"69.8","eosinophil":"18.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"17","RNA blood lineage specific nTPM":{"granulocytes":"69.8"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"U-937":"17.6"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"4.3","Tissue RNA - breast [nTPM]":"0.6","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"4.7","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"23.9","Tissue RNA - small intestine [nTPM]":"0.9","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.7","Tissue RNA - stomach 1 [nTPM]":"1.7","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.7","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"3.9","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"17.6","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"69.8","Blood RNA - classical monocyte [nTPM]":"4.0","Blood RNA - eosinophil [nTPM]":"18.9","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"2.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"1.8","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"6.2","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"1.1","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"PNPLA2","Gene synonym":["ATGL","desnutrin","FP17548","iPLA2zeta","TTS-2.2"],"Ensembl":"ENSG00000177666","Gene description":"Patatin like phospholipase domain containing 2","Uniprot":["Q96AD5"],"Chromosome":"11","Position":"818914-825573","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"508.1","breast":"361.4"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"194.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055173","HPA062602","HPA075175"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Lipid droplets"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Lipid droplets"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA055173":"AB_2682725","HPA062602":"AB_2684804","HPA075175":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Tissue RNA - adipose tissue [nTPM]":"508.1","Tissue RNA - adrenal gland [nTPM]":"75.3","Tissue RNA - amygdala [nTPM]":"11.9","Tissue RNA - appendix [nTPM]":"9.2","Tissue RNA - basal ganglia [nTPM]":"14.0","Tissue RNA - bone marrow [nTPM]":"43.1","Tissue RNA - breast [nTPM]":"361.4","Tissue RNA - cerebellum [nTPM]":"13.6","Tissue RNA - cerebral cortex [nTPM]":"18.8","Tissue RNA - cervix [nTPM]":"42.2","Tissue RNA - choroid plexus [nTPM]":"13.4","Tissue RNA - colon [nTPM]":"58.1","Tissue RNA - duodenum [nTPM]":"19.3","Tissue RNA - endometrium 1 [nTPM]":"49.2","Tissue RNA - epididymis [nTPM]":"2.8","Tissue RNA - esophagus [nTPM]":"39.9","Tissue RNA - fallopian tube [nTPM]":"50.8","Tissue RNA - gallbladder [nTPM]":"9.5","Tissue RNA - heart muscle [nTPM]":"171.3","Tissue RNA - hippocampal formation [nTPM]":"11.9","Tissue RNA - hypothalamus [nTPM]":"14.0","Tissue RNA - kidney [nTPM]":"61.9","Tissue RNA - liver [nTPM]":"58.4","Tissue RNA - lung [nTPM]":"57.3","Tissue RNA - lymph node [nTPM]":"8.1","Tissue RNA - medulla oblongata [nTPM]":"17.5","Tissue RNA - midbrain [nTPM]":"11.8","Tissue RNA - ovary [nTPM]":"50.5","Tissue RNA - pancreas [nTPM]":"75.4","Tissue RNA - parathyroid gland [nTPM]":"9.6","Tissue RNA - pituitary gland [nTPM]":"46.3","Tissue RNA - placenta [nTPM]":"8.4","Tissue RNA - pons [nTPM]":"16.8","Tissue RNA - prostate [nTPM]":"46.6","Tissue RNA - rectum [nTPM]":"4.8","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"81.1","Tissue RNA - seminal vesicle [nTPM]":"16.7","Tissue RNA - skeletal muscle [nTPM]":"194.6","Tissue RNA - skin 1 [nTPM]":"71.8","Tissue RNA - small intestine [nTPM]":"74.7","Tissue RNA - smooth muscle [nTPM]":"6.4","Tissue RNA - spinal cord [nTPM]":"12.6","Tissue RNA - spleen [nTPM]":"51.2","Tissue RNA - stomach 1 [nTPM]":"71.3","Tissue RNA - testis [nTPM]":"32.1","Tissue RNA - thalamus [nTPM]":"12.8","Tissue RNA - thymus [nTPM]":"10.9","Tissue RNA - thyroid gland [nTPM]":"55.3","Tissue RNA - tongue [nTPM]":"64.3","Tissue RNA - tonsil [nTPM]":"4.1","Tissue RNA - urinary bladder [nTPM]":"64.8","Tissue RNA - vagina [nTPM]":"44.5","Tissue RNA - white matter [nTPM]":"15.3","Cell RNA - A-431 [nTPM]":"33.9","Cell RNA - A549 [nTPM]":"26.0","Cell RNA - AF22 [nTPM]":"5.3","Cell RNA - AN3-CA [nTPM]":"14.0","Cell RNA - ASC diff [nTPM]":"194.4","Cell RNA - ASC TERT1 [nTPM]":"17.2","Cell RNA - BEWO [nTPM]":"34.1","Cell RNA - BJ [nTPM]":"35.3","Cell RNA - BJ hTERT+ [nTPM]":"28.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.1","Cell RNA - CACO-2 [nTPM]":"22.3","Cell RNA - CAPAN-2 [nTPM]":"33.3","Cell RNA - Daudi [nTPM]":"19.9","Cell RNA - EFO-21 [nTPM]":"20.4","Cell RNA - fHDF\/TERT166 [nTPM]":"26.7","Cell RNA - GAMG [nTPM]":"13.6","Cell RNA - HaCaT [nTPM]":"30.0","Cell RNA - HAP1 [nTPM]":"8.1","Cell RNA - HBEC3-KT [nTPM]":"14.6","Cell RNA - HBF TERT88 [nTPM]":"6.6","Cell RNA - HDLM-2 [nTPM]":"25.9","Cell RNA - HEK 293 [nTPM]":"71.5","Cell RNA - HEL [nTPM]":"27.6","Cell RNA - HeLa [nTPM]":"11.2","Cell RNA - Hep G2 [nTPM]":"36.3","Cell RNA - HHSteC [nTPM]":"63.3","Cell RNA - HL-60 [nTPM]":"19.2","Cell RNA - HMC-1 [nTPM]":"33.4","Cell RNA - HSkMC [nTPM]":"33.9","Cell RNA - hTCEpi [nTPM]":"18.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.5","Cell RNA - hTERT-HME1 [nTPM]":"16.7","Cell RNA - hTERT-RPE1 [nTPM]":"22.3","Cell RNA - HUVEC TERT2 [nTPM]":"17.7","Cell RNA - JURKAT [nTPM]":"14.5","Cell RNA - K-562 [nTPM]":"23.8","Cell RNA - Karpas-707 [nTPM]":"19.9","Cell RNA - LHCN-M2 [nTPM]":"19.5","Cell RNA - MCF7 [nTPM]":"20.0","Cell RNA - MOLT-4 [nTPM]":"25.8","Cell RNA - NB-4 [nTPM]":"42.3","Cell RNA - NTERA-2 [nTPM]":"15.2","Cell RNA - OE19 [nTPM]":"34.3","Cell RNA - PC-3 [nTPM]":"55.1","Cell RNA - REH [nTPM]":"24.6","Cell RNA - RH-30 [nTPM]":"11.5","Cell RNA - RPMI-8226 [nTPM]":"45.7","Cell RNA - RPTEC TERT1 [nTPM]":"21.4","Cell RNA - RT4 [nTPM]":"7.7","Cell RNA - SCLC-21H [nTPM]":"19.6","Cell RNA - SH-SY5Y [nTPM]":"26.0","Cell RNA - SiHa [nTPM]":"65.3","Cell RNA - SK-BR-3 [nTPM]":"55.0","Cell RNA - SK-MEL-30 [nTPM]":"21.9","Cell RNA - SuSa [nTPM]":"3.4","Cell RNA - T-47d [nTPM]":"23.7","Cell RNA - THP-1 [nTPM]":"22.0","Cell RNA - TIME [nTPM]":"32.5","Cell RNA - U-138 MG [nTPM]":"19.3","Cell RNA - U-2 OS [nTPM]":"15.0","Cell RNA - U-2197 [nTPM]":"12.7","Cell RNA - U-251 MG [nTPM]":"16.3","Cell RNA - U-266\/70 [nTPM]":"75.2","Cell RNA - U-266\/84 [nTPM]":"49.8","Cell RNA - U-698 [nTPM]":"16.7","Cell RNA - U-87 MG [nTPM]":"48.4","Cell RNA - U-937 [nTPM]":"27.0","Cell RNA - WM-115 [nTPM]":"13.8","Blood RNA - basophil [nTPM]":"11.5","Blood RNA - classical monocyte [nTPM]":"9.5","Blood RNA - eosinophil [nTPM]":"22.1","Blood RNA - gdT-cell [nTPM]":"3.7","Blood RNA - intermediate monocyte [nTPM]":"6.1","Blood RNA - MAIT T-cell [nTPM]":"3.6","Blood RNA - memory B-cell [nTPM]":"4.7","Blood RNA - memory CD4 T-cell [nTPM]":"4.8","Blood RNA - memory CD8 T-cell [nTPM]":"5.4","Blood RNA - myeloid DC [nTPM]":"6.1","Blood RNA - naive B-cell [nTPM]":"4.1","Blood RNA - naive CD4 T-cell [nTPM]":"5.4","Blood RNA - naive CD8 T-cell [nTPM]":"4.4","Blood RNA - neutrophil [nTPM]":"8.2","Blood RNA - NK-cell [nTPM]":"4.0","Blood RNA - non-classical monocyte [nTPM]":"7.1","Blood RNA - plasmacytoid DC [nTPM]":"7.0","Blood RNA - T-reg [nTPM]":"4.2","Blood RNA - total PBMC [nTPM]":"4.7","Brain RNA - amygdala [nTPM]":"11.9","Brain RNA - basal ganglia [nTPM]":"14.0","Brain RNA - cerebellum [nTPM]":"13.6","Brain RNA - cerebral cortex [nTPM]":"18.8","Brain RNA - hippocampal formation [nTPM]":"11.9","Brain RNA - hypothalamus [nTPM]":"14.0","Brain RNA - medulla oblongata [nTPM]":"17.5","Brain RNA - midbrain [nTPM]":"11.8","Brain RNA - pons [nTPM]":"16.8","Brain RNA - spinal cord [nTPM]":"12.6","Brain RNA - thalamus [nTPM]":"12.8","Brain RNA - white matter [nTPM]":"15.3","Single Cell Type RNA - Adipocytes [nTPM]":"78.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.8","Single Cell Type RNA - Astrocytes [nTPM]":"12.7","Single Cell Type RNA - B-cells [nTPM]":"63.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"44.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"69.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"34.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"42.1","Single Cell Type RNA - Bipolar cells [nTPM]":"14.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"79.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"67.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"45.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"61.5","Single Cell Type RNA - Club cells [nTPM]":"65.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"51.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"70.2","Single Cell Type RNA - dendritic cells [nTPM]":"50.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"151.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"65.1","Single Cell Type RNA - Early spermatids [nTPM]":"22.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"58.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"31.8","Single Cell Type RNA - Endothelial cells [nTPM]":"51.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"51.5","Single Cell Type RNA - Erythroid cells [nTPM]":"52.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"65.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"32.0","Single Cell Type RNA - Fibroblasts [nTPM]":"37.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"204.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"114.3","Single Cell Type RNA - granulocytes [nTPM]":"11.4","Single Cell Type RNA - Granulosa cells [nTPM]":"42.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"100.6","Single Cell Type RNA - Hepatocytes [nTPM]":"50.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"29.2","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"96.1","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"27.6","Single Cell Type RNA - Langerhans cells [nTPM]":"29.0","Single Cell Type RNA - Late spermatids [nTPM]":"6.2","Single Cell Type RNA - Leydig cells [nTPM]":"48.4","Single Cell Type RNA - Macrophages [nTPM]":"46.6","Single Cell Type RNA - Melanocytes [nTPM]":"42.7","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"29.6","Single Cell Type RNA - Muller glia cells [nTPM]":"32.2","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"13.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"142.2","Single Cell Type RNA - Paneth cells [nTPM]":"170.7","Single Cell Type RNA - Peritubular cells [nTPM]":"39.1","Single Cell Type RNA - Plasma cells [nTPM]":"92.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"78.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"166.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"45.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"31.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.0","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"64.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"50.7","Single Cell Type RNA - Spermatocytes [nTPM]":"33.5","Single Cell Type RNA - Spermatogonia [nTPM]":"23.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"53.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"41.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"169.4","Single Cell Type RNA - T-cells [nTPM]":"53.3","Single Cell Type RNA - Theca cells [nTPM]":"182.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"43.6","Single Cell Type RNA - Urothelial cells [nTPM]":"195.5"},{"Gene":"PNPLA3","Gene synonym":["adiponutrin","ADPN","C22orf20","dJ796I17.1","FLJ22012","iPLA2epsilon"],"Ensembl":"ENSG00000100344","Gene description":"Patatin like phospholipase domain containing 3","Uniprot":["Q9NST1"],"Chromosome":"22","Position":"43923792-43964488","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Acyltransferase","Hydrolase","Transferase"],"Disease involvement":["Disease variant","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"liver":"31.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"35.9","Cone photoreceptor cells":"18.8","Hepatocytes":"42.3","Rod photoreceptor cells":"37.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"4.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"16.7","LHCN-M2":"19.3"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebellum":"12.2"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058058"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Mitochondria","Cytosol"],"Antibody RRID":{"HPA058058":"AB_2683590"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Tissue RNA - adipose tissue [nTPM]":"2.6","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.6","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"0.8","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"1.6","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"1.2","Tissue RNA - cervix [nTPM]":"0.6","Tissue RNA - choroid plexus [nTPM]":"5.9","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.8","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"1.2","Tissue RNA - hypothalamus [nTPM]":"0.7","Tissue RNA - kidney [nTPM]":"4.5","Tissue RNA - liver [nTPM]":"31.0","Tissue RNA - lung [nTPM]":"0.8","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"1.7","Tissue RNA - midbrain [nTPM]":"1.8","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"2.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"6.4","Tissue RNA - salivary gland [nTPM]":"0.7","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"1.7","Tissue RNA - skin 1 [nTPM]":"5.8","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"1.3","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"5.1","Cell RNA - A549 [nTPM]":"1.6","Cell RNA - AF22 [nTPM]":"16.7","Cell RNA - AN3-CA [nTPM]":"6.8","Cell RNA - ASC diff [nTPM]":"4.6","Cell RNA - ASC TERT1 [nTPM]":"5.2","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"3.1","Cell RNA - BJ hTERT+ [nTPM]":"1.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.8","Cell RNA - CACO-2 [nTPM]":"5.0","Cell RNA - CAPAN-2 [nTPM]":"9.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"2.5","Cell RNA - fHDF\/TERT166 [nTPM]":"5.2","Cell RNA - GAMG [nTPM]":"2.4","Cell RNA - HaCaT [nTPM]":"4.3","Cell RNA - HAP1 [nTPM]":"10.6","Cell RNA - HBEC3-KT [nTPM]":"5.0","Cell RNA - HBF TERT88 [nTPM]":"3.4","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.9","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"4.5","Cell RNA - Hep G2 [nTPM]":"9.4","Cell RNA - HHSteC [nTPM]":"7.5","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"6.0","Cell RNA - hTCEpi [nTPM]":"3.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.2","Cell RNA - hTERT-HME1 [nTPM]":"0.6","Cell RNA - hTERT-RPE1 [nTPM]":"7.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.5","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"19.3","Cell RNA - MCF7 [nTPM]":"0.7","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"11.5","Cell RNA - OE19 [nTPM]":"0.6","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"8.9","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"1.7","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"1.5","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"3.4","Cell RNA - SK-BR-3 [nTPM]":"1.4","Cell RNA - SK-MEL-30 [nTPM]":"4.8","Cell RNA - SuSa [nTPM]":"2.9","Cell RNA - T-47d [nTPM]":"5.3","Cell RNA - THP-1 [nTPM]":"5.8","Cell RNA - TIME [nTPM]":"0.6","Cell RNA - U-138 MG [nTPM]":"1.6","Cell RNA - U-2 OS [nTPM]":"4.9","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"14.3","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"6.0","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.6","Brain RNA - basal ganglia [nTPM]":"0.8","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"1.2","Brain RNA - hippocampal formation [nTPM]":"1.2","Brain RNA - hypothalamus [nTPM]":"0.7","Brain RNA - medulla oblongata [nTPM]":"1.7","Brain RNA - midbrain [nTPM]":"1.8","Brain RNA - pons [nTPM]":"2.0","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"1.3","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"4.2","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"35.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"1.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"42.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.9","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"37.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"1.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"PNPLA4","Gene synonym":["DXS1283E","GS2","iPLA2eta"],"Ensembl":"ENSG00000006757","Gene description":"Patatin like phospholipase domain containing 4","Uniprot":["P41247"],"Chromosome":"X","Position":"7898247-7927739","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"95.9","Proximal tubular cells":"126.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003656"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA003656":"AB_1079033"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.29e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.37e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.23e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Tissue RNA - adipose tissue [nTPM]":"20.8","Tissue RNA - adrenal gland [nTPM]":"27.6","Tissue RNA - amygdala [nTPM]":"11.9","Tissue RNA - appendix [nTPM]":"9.7","Tissue RNA - basal ganglia [nTPM]":"12.6","Tissue RNA - bone marrow [nTPM]":"8.7","Tissue RNA - breast [nTPM]":"22.6","Tissue RNA - cerebellum [nTPM]":"12.0","Tissue RNA - cerebral cortex [nTPM]":"11.8","Tissue RNA - cervix [nTPM]":"13.9","Tissue RNA - choroid plexus [nTPM]":"16.9","Tissue RNA - colon [nTPM]":"15.4","Tissue RNA - duodenum [nTPM]":"18.9","Tissue RNA - endometrium 1 [nTPM]":"14.0","Tissue RNA - epididymis [nTPM]":"18.1","Tissue RNA - esophagus [nTPM]":"21.0","Tissue RNA - fallopian tube [nTPM]":"24.7","Tissue RNA - gallbladder [nTPM]":"9.4","Tissue RNA - heart muscle [nTPM]":"42.1","Tissue RNA - hippocampal formation [nTPM]":"11.1","Tissue RNA - hypothalamus [nTPM]":"14.2","Tissue RNA - kidney [nTPM]":"41.2","Tissue RNA - liver [nTPM]":"40.1","Tissue RNA - lung [nTPM]":"9.8","Tissue RNA - lymph node [nTPM]":"10.8","Tissue RNA - medulla oblongata [nTPM]":"12.1","Tissue RNA - midbrain [nTPM]":"13.5","Tissue RNA - ovary [nTPM]":"22.4","Tissue RNA - pancreas [nTPM]":"28.8","Tissue RNA - parathyroid gland [nTPM]":"25.2","Tissue RNA - pituitary gland [nTPM]":"13.5","Tissue RNA - placenta [nTPM]":"8.0","Tissue RNA - pons [nTPM]":"12.4","Tissue RNA - prostate [nTPM]":"12.8","Tissue RNA - rectum [nTPM]":"12.3","Tissue RNA - retina [nTPM]":"16.8","Tissue RNA - salivary gland [nTPM]":"26.9","Tissue RNA - seminal vesicle [nTPM]":"10.8","Tissue RNA - skeletal muscle [nTPM]":"77.9","Tissue RNA - skin 1 [nTPM]":"15.0","Tissue RNA - small intestine [nTPM]":"11.4","Tissue RNA - smooth muscle [nTPM]":"12.1","Tissue RNA - spinal cord [nTPM]":"12.5","Tissue RNA - spleen [nTPM]":"9.4","Tissue RNA - stomach 1 [nTPM]":"19.5","Tissue RNA - testis [nTPM]":"7.8","Tissue RNA - thalamus [nTPM]":"15.6","Tissue RNA - thymus [nTPM]":"16.3","Tissue RNA - thyroid gland [nTPM]":"29.9","Tissue RNA - tongue [nTPM]":"66.0","Tissue RNA - tonsil [nTPM]":"10.2","Tissue RNA - urinary bladder [nTPM]":"8.9","Tissue RNA - vagina [nTPM]":"13.3","Tissue RNA - white matter [nTPM]":"11.9","Cell RNA - A-431 [nTPM]":"44.7","Cell RNA - A549 [nTPM]":"18.1","Cell RNA - AF22 [nTPM]":"2.8","Cell RNA - AN3-CA [nTPM]":"44.4","Cell RNA - ASC diff [nTPM]":"0.9","Cell RNA - ASC TERT1 [nTPM]":"0.5","Cell RNA - BEWO [nTPM]":"11.9","Cell RNA - BJ [nTPM]":"13.7","Cell RNA - BJ hTERT+ [nTPM]":"1.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.1","Cell RNA - CACO-2 [nTPM]":"18.1","Cell RNA - CAPAN-2 [nTPM]":"16.1","Cell RNA - Daudi [nTPM]":"13.9","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"4.5","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"25.7","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"45.6","Cell RNA - HBF TERT88 [nTPM]":"39.2","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"32.0","Cell RNA - HEL [nTPM]":"10.0","Cell RNA - HeLa [nTPM]":"32.8","Cell RNA - Hep G2 [nTPM]":"38.6","Cell RNA - HHSteC [nTPM]":"28.6","Cell RNA - HL-60 [nTPM]":"17.8","Cell RNA - HMC-1 [nTPM]":"14.1","Cell RNA - HSkMC [nTPM]":"29.5","Cell RNA - hTCEpi [nTPM]":"45.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.7","Cell RNA - hTERT-HME1 [nTPM]":"27.3","Cell RNA - hTERT-RPE1 [nTPM]":"5.5","Cell RNA - HUVEC TERT2 [nTPM]":"16.2","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"39.9","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"0.3","Cell RNA - MCF7 [nTPM]":"11.8","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"17.2","Cell RNA - NTERA-2 [nTPM]":"46.9","Cell RNA - OE19 [nTPM]":"30.7","Cell RNA - PC-3 [nTPM]":"38.0","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"15.6","Cell RNA - RPTEC TERT1 [nTPM]":"30.6","Cell RNA - RT4 [nTPM]":"20.3","Cell RNA - SCLC-21H [nTPM]":"25.3","Cell RNA - SH-SY5Y [nTPM]":"12.7","Cell RNA - SiHa [nTPM]":"41.2","Cell RNA - SK-BR-3 [nTPM]":"16.8","Cell RNA - SK-MEL-30 [nTPM]":"23.7","Cell RNA - SuSa [nTPM]":"49.7","Cell RNA - T-47d [nTPM]":"26.1","Cell RNA - THP-1 [nTPM]":"13.0","Cell RNA - TIME [nTPM]":"9.4","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"11.4","Cell RNA - U-2197 [nTPM]":"35.5","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"20.3","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"27.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"3.7","Blood RNA - basophil [nTPM]":"7.4","Blood RNA - classical monocyte [nTPM]":"11.4","Blood RNA - eosinophil [nTPM]":"9.7","Blood RNA - gdT-cell [nTPM]":"6.1","Blood RNA - intermediate monocyte [nTPM]":"13.5","Blood RNA - MAIT T-cell [nTPM]":"7.0","Blood RNA - memory B-cell [nTPM]":"14.7","Blood RNA - memory CD4 T-cell [nTPM]":"8.7","Blood RNA - memory CD8 T-cell [nTPM]":"6.7","Blood RNA - myeloid DC [nTPM]":"22.2","Blood RNA - naive B-cell [nTPM]":"16.7","Blood RNA - naive CD4 T-cell [nTPM]":"11.3","Blood RNA - naive CD8 T-cell [nTPM]":"10.8","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"11.9","Blood RNA - non-classical monocyte [nTPM]":"12.5","Blood RNA - plasmacytoid DC [nTPM]":"16.3","Blood RNA - T-reg [nTPM]":"6.0","Blood RNA - total PBMC [nTPM]":"9.3","Brain RNA - amygdala [nTPM]":"11.9","Brain RNA - basal ganglia [nTPM]":"12.6","Brain RNA - cerebellum [nTPM]":"12.0","Brain RNA - cerebral cortex [nTPM]":"11.8","Brain RNA - hippocampal formation [nTPM]":"11.1","Brain RNA - hypothalamus [nTPM]":"14.2","Brain RNA - medulla oblongata [nTPM]":"12.1","Brain RNA - midbrain [nTPM]":"13.5","Brain RNA - pons [nTPM]":"12.4","Brain RNA - spinal cord [nTPM]":"12.5","Brain RNA - thalamus [nTPM]":"15.6","Brain RNA - white matter [nTPM]":"11.9","Single Cell Type RNA - Adipocytes [nTPM]":"10.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.5","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"8.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"46.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.6","Single Cell Type RNA - Bipolar cells [nTPM]":"11.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"38.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"33.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"55.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"24.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"28.7","Single Cell Type RNA - dendritic cells [nTPM]":"7.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"31.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"95.9","Single Cell Type RNA - Ductal cells [nTPM]":"34.2","Single Cell Type RNA - Early spermatids [nTPM]":"3.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"35.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.6","Single Cell Type RNA - Endothelial cells [nTPM]":"10.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.8","Single Cell Type RNA - Erythroid cells [nTPM]":"15.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"48.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.3","Single Cell Type RNA - Fibroblasts [nTPM]":"14.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.5","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"17.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.2","Single Cell Type RNA - Hepatocytes [nTPM]":"62.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.7","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"30.6","Single Cell Type RNA - Ionocytes [nTPM]":"38.7","Single Cell Type RNA - Kupffer cells [nTPM]":"9.2","Single Cell Type RNA - Langerhans cells [nTPM]":"10.2","Single Cell Type RNA - Late spermatids [nTPM]":"3.7","Single Cell Type RNA - Leydig cells [nTPM]":"16.4","Single Cell Type RNA - Macrophages [nTPM]":"12.1","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"13.3","Single Cell Type RNA - Muller glia cells [nTPM]":"36.1","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"39.8","Single Cell Type RNA - Paneth cells [nTPM]":"25.1","Single Cell Type RNA - Peritubular cells [nTPM]":"20.3","Single Cell Type RNA - Plasma cells [nTPM]":"14.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"47.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"126.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"31.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.6","Single Cell Type RNA - Spermatocytes [nTPM]":"22.2","Single Cell Type RNA - Spermatogonia [nTPM]":"21.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"24.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.0","Single Cell Type RNA - T-cells [nTPM]":"6.4","Single Cell Type RNA - Theca cells [nTPM]":"49.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"32.3","Single Cell Type RNA - Urothelial cells [nTPM]":"16.0"},{"Gene":"PNPLA6","Gene synonym":["iPLA2delta","NTE","SPG39","sws"],"Ensembl":"ENSG00000032444","Gene description":"Patatin like phospholipase domain containing 6","Uniprot":["Q8IY17"],"Chromosome":"19","Position":"7534004-7561764","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Dwarfism","Hereditary spastic paraplegia","Hypogonadotropic hypogonadism","Mental retardation","Neurodegeneration","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"73.4","Late spermatids":"106.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007522","HPA064773"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Endoplasmic reticulum","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA007522":"AB_1079649","HPA064773":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.25e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.51e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.53e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Tissue RNA - adipose tissue [nTPM]":"17.9","Tissue RNA - adrenal gland [nTPM]":"27.3","Tissue RNA - amygdala [nTPM]":"18.3","Tissue RNA - appendix [nTPM]":"26.2","Tissue RNA - basal ganglia [nTPM]":"23.2","Tissue RNA - bone marrow [nTPM]":"26.1","Tissue RNA - breast [nTPM]":"16.4","Tissue RNA - cerebellum [nTPM]":"14.7","Tissue RNA - cerebral cortex [nTPM]":"31.5","Tissue RNA - cervix [nTPM]":"20.2","Tissue RNA - choroid plexus [nTPM]":"12.6","Tissue RNA - colon [nTPM]":"25.7","Tissue RNA - duodenum [nTPM]":"26.9","Tissue RNA - endometrium 1 [nTPM]":"20.8","Tissue RNA - epididymis [nTPM]":"5.3","Tissue RNA - esophagus [nTPM]":"20.4","Tissue RNA - fallopian tube [nTPM]":"16.8","Tissue RNA - gallbladder [nTPM]":"13.7","Tissue RNA - heart muscle [nTPM]":"20.7","Tissue RNA - hippocampal formation [nTPM]":"21.9","Tissue RNA - hypothalamus [nTPM]":"16.3","Tissue RNA - kidney [nTPM]":"25.6","Tissue RNA - liver [nTPM]":"21.9","Tissue RNA - lung [nTPM]":"40.4","Tissue RNA - lymph node [nTPM]":"19.5","Tissue RNA - medulla oblongata [nTPM]":"23.4","Tissue RNA - midbrain [nTPM]":"20.3","Tissue RNA - ovary [nTPM]":"18.8","Tissue RNA - pancreas [nTPM]":"16.4","Tissue RNA - parathyroid gland [nTPM]":"15.6","Tissue RNA - pituitary gland [nTPM]":"32.7","Tissue RNA - placenta [nTPM]":"13.6","Tissue RNA - pons [nTPM]":"25.6","Tissue RNA - prostate [nTPM]":"21.4","Tissue RNA - rectum [nTPM]":"8.4","Tissue RNA - retina [nTPM]":"10.6","Tissue RNA - salivary gland [nTPM]":"15.8","Tissue RNA - seminal vesicle [nTPM]":"12.8","Tissue RNA - skeletal muscle [nTPM]":"33.5","Tissue RNA - skin 1 [nTPM]":"17.5","Tissue RNA - small intestine [nTPM]":"29.6","Tissue RNA - smooth muscle [nTPM]":"14.5","Tissue RNA - spinal cord [nTPM]":"10.1","Tissue RNA - spleen [nTPM]":"41.9","Tissue RNA - stomach 1 [nTPM]":"19.2","Tissue RNA - testis [nTPM]":"36.4","Tissue RNA - thalamus [nTPM]":"23.7","Tissue RNA - thymus [nTPM]":"10.9","Tissue RNA - thyroid gland [nTPM]":"22.7","Tissue RNA - tongue [nTPM]":"19.5","Tissue RNA - tonsil [nTPM]":"8.9","Tissue RNA - urinary bladder [nTPM]":"24.6","Tissue RNA - vagina [nTPM]":"17.4","Tissue RNA - white matter [nTPM]":"23.6","Cell RNA - A-431 [nTPM]":"32.4","Cell RNA - A549 [nTPM]":"80.1","Cell RNA - AF22 [nTPM]":"14.7","Cell RNA - AN3-CA [nTPM]":"36.1","Cell RNA - ASC diff [nTPM]":"25.5","Cell RNA - ASC TERT1 [nTPM]":"37.0","Cell RNA - BEWO [nTPM]":"34.3","Cell RNA - BJ [nTPM]":"42.2","Cell RNA - BJ hTERT+ [nTPM]":"41.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"31.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"28.8","Cell RNA - CACO-2 [nTPM]":"18.6","Cell RNA - CAPAN-2 [nTPM]":"43.7","Cell RNA - Daudi [nTPM]":"27.3","Cell RNA - EFO-21 [nTPM]":"69.1","Cell RNA - fHDF\/TERT166 [nTPM]":"55.3","Cell RNA - GAMG [nTPM]":"19.7","Cell RNA - HaCaT [nTPM]":"40.8","Cell RNA - HAP1 [nTPM]":"13.1","Cell RNA - HBEC3-KT [nTPM]":"39.4","Cell RNA - HBF TERT88 [nTPM]":"16.3","Cell RNA - HDLM-2 [nTPM]":"68.5","Cell RNA - HEK 293 [nTPM]":"29.2","Cell RNA - HEL [nTPM]":"17.7","Cell RNA - HeLa [nTPM]":"41.8","Cell RNA - Hep G2 [nTPM]":"13.9","Cell RNA - HHSteC [nTPM]":"29.2","Cell RNA - HL-60 [nTPM]":"20.2","Cell RNA - HMC-1 [nTPM]":"53.0","Cell RNA - HSkMC [nTPM]":"31.6","Cell RNA - hTCEpi [nTPM]":"22.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"41.8","Cell RNA - hTERT-HME1 [nTPM]":"23.8","Cell RNA - hTERT-RPE1 [nTPM]":"49.2","Cell RNA - HUVEC TERT2 [nTPM]":"62.7","Cell RNA - JURKAT [nTPM]":"31.4","Cell RNA - K-562 [nTPM]":"14.9","Cell RNA - Karpas-707 [nTPM]":"36.5","Cell RNA - LHCN-M2 [nTPM]":"28.6","Cell RNA - MCF7 [nTPM]":"15.7","Cell RNA - MOLT-4 [nTPM]":"22.2","Cell RNA - NB-4 [nTPM]":"26.0","Cell RNA - NTERA-2 [nTPM]":"16.2","Cell RNA - OE19 [nTPM]":"15.5","Cell RNA - PC-3 [nTPM]":"71.7","Cell RNA - REH [nTPM]":"17.3","Cell RNA - RH-30 [nTPM]":"9.0","Cell RNA - RPMI-8226 [nTPM]":"31.9","Cell RNA - RPTEC TERT1 [nTPM]":"27.9","Cell RNA - RT4 [nTPM]":"31.2","Cell RNA - SCLC-21H [nTPM]":"19.0","Cell RNA - SH-SY5Y [nTPM]":"32.5","Cell RNA - SiHa [nTPM]":"34.9","Cell RNA - SK-BR-3 [nTPM]":"15.7","Cell RNA - SK-MEL-30 [nTPM]":"45.6","Cell RNA - SuSa [nTPM]":"20.4","Cell RNA - T-47d [nTPM]":"14.1","Cell RNA - THP-1 [nTPM]":"27.6","Cell RNA - TIME [nTPM]":"67.0","Cell RNA - U-138 MG [nTPM]":"38.5","Cell RNA - U-2 OS [nTPM]":"22.1","Cell RNA - U-2197 [nTPM]":"53.3","Cell RNA - U-251 MG [nTPM]":"44.2","Cell RNA - U-266\/70 [nTPM]":"42.6","Cell RNA - U-266\/84 [nTPM]":"30.1","Cell RNA - U-698 [nTPM]":"12.2","Cell RNA - U-87 MG [nTPM]":"64.2","Cell RNA - U-937 [nTPM]":"23.2","Cell RNA - WM-115 [nTPM]":"36.7","Blood RNA - basophil [nTPM]":"15.7","Blood RNA - classical monocyte [nTPM]":"11.3","Blood RNA - eosinophil [nTPM]":"37.6","Blood RNA - gdT-cell [nTPM]":"5.4","Blood RNA - intermediate monocyte [nTPM]":"20.0","Blood RNA - MAIT T-cell [nTPM]":"5.5","Blood RNA - memory B-cell [nTPM]":"6.5","Blood RNA - memory CD4 T-cell [nTPM]":"3.8","Blood RNA - memory CD8 T-cell [nTPM]":"5.7","Blood RNA - myeloid DC [nTPM]":"12.1","Blood RNA - naive B-cell [nTPM]":"4.3","Blood RNA - naive CD4 T-cell [nTPM]":"3.3","Blood RNA - naive CD8 T-cell [nTPM]":"4.5","Blood RNA - neutrophil [nTPM]":"3.2","Blood RNA - NK-cell [nTPM]":"7.9","Blood RNA - non-classical monocyte [nTPM]":"35.0","Blood RNA - plasmacytoid DC [nTPM]":"3.8","Blood RNA - T-reg [nTPM]":"6.9","Blood RNA - total PBMC [nTPM]":"8.8","Brain RNA - amygdala [nTPM]":"18.3","Brain RNA - basal ganglia [nTPM]":"23.2","Brain RNA - cerebellum [nTPM]":"14.7","Brain RNA - cerebral cortex [nTPM]":"31.5","Brain RNA - hippocampal formation [nTPM]":"21.9","Brain RNA - hypothalamus [nTPM]":"16.3","Brain RNA - medulla oblongata [nTPM]":"23.4","Brain RNA - midbrain [nTPM]":"20.3","Brain RNA - pons [nTPM]":"25.6","Brain RNA - spinal cord [nTPM]":"10.1","Brain RNA - thalamus [nTPM]":"23.7","Brain RNA - white matter [nTPM]":"23.6","Single Cell Type RNA - Adipocytes [nTPM]":"12.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.0","Single Cell Type RNA - Astrocytes [nTPM]":"16.6","Single Cell Type RNA - B-cells [nTPM]":"11.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"12.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"10.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.2","Single Cell Type RNA - dendritic cells [nTPM]":"14.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"48.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"15.8","Single Cell Type RNA - Early spermatids [nTPM]":"73.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.2","Single Cell Type RNA - Endothelial cells [nTPM]":"13.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.4","Single Cell Type RNA - Erythroid cells [nTPM]":"25.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.5","Single Cell Type RNA - Fibroblasts [nTPM]":"7.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.7","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"19.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"20.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"27.4","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"16.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.6","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"68.3","Single Cell Type RNA - Langerhans cells [nTPM]":"16.0","Single Cell Type RNA - Late spermatids [nTPM]":"106.1","Single Cell Type RNA - Leydig cells [nTPM]":"9.6","Single Cell Type RNA - Macrophages [nTPM]":"42.4","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"23.6","Single Cell Type RNA - Muller glia cells [nTPM]":"9.2","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.5","Single Cell Type RNA - Paneth cells [nTPM]":"17.9","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"8.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"67.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.7","Single Cell Type RNA - Spermatocytes [nTPM]":"60.8","Single Cell Type RNA - Spermatogonia [nTPM]":"10.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.4","Single Cell Type RNA - T-cells [nTPM]":"15.9","Single Cell Type RNA - Theca cells [nTPM]":"10.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.9","Single Cell Type RNA - Urothelial cells [nTPM]":"3.6"},{"Gene":"PNPLA8","Gene synonym":["IPLA2-2","IPLA2G","iPLA2gamma"],"Ensembl":"ENSG00000135241","Gene description":"Patatin like phospholipase domain containing 8","Uniprot":["Q9NP80"],"Chromosome":"7","Position":"108470417-108569666","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Glandular and luminal cells":"236.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020083"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA020083":"AB_1851849"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.86e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Tissue RNA - adipose tissue [nTPM]":"27.8","Tissue RNA - adrenal gland [nTPM]":"47.3","Tissue RNA - amygdala [nTPM]":"23.6","Tissue RNA - appendix [nTPM]":"17.9","Tissue RNA - basal ganglia [nTPM]":"25.1","Tissue RNA - bone marrow [nTPM]":"82.9","Tissue RNA - breast [nTPM]":"20.2","Tissue RNA - cerebellum [nTPM]":"21.6","Tissue RNA - cerebral cortex [nTPM]":"29.6","Tissue RNA - cervix [nTPM]":"19.4","Tissue RNA - choroid plexus [nTPM]":"22.1","Tissue RNA - colon [nTPM]":"14.1","Tissue RNA - duodenum [nTPM]":"11.8","Tissue RNA - endometrium 1 [nTPM]":"17.9","Tissue RNA - epididymis [nTPM]":"17.7","Tissue RNA - esophagus [nTPM]":"21.1","Tissue RNA - fallopian tube [nTPM]":"11.6","Tissue RNA - gallbladder [nTPM]":"21.4","Tissue RNA - heart muscle [nTPM]":"25.3","Tissue RNA - hippocampal formation [nTPM]":"24.0","Tissue RNA - hypothalamus [nTPM]":"26.5","Tissue RNA - kidney [nTPM]":"30.0","Tissue RNA - liver [nTPM]":"34.6","Tissue RNA - lung [nTPM]":"17.5","Tissue RNA - lymph node [nTPM]":"18.0","Tissue RNA - medulla oblongata [nTPM]":"23.5","Tissue RNA - midbrain [nTPM]":"23.3","Tissue RNA - ovary [nTPM]":"14.7","Tissue RNA - pancreas [nTPM]":"13.9","Tissue RNA - parathyroid gland [nTPM]":"28.4","Tissue RNA - pituitary gland [nTPM]":"16.5","Tissue RNA - placenta [nTPM]":"26.6","Tissue RNA - pons [nTPM]":"23.4","Tissue RNA - prostate [nTPM]":"18.0","Tissue RNA - rectum [nTPM]":"15.1","Tissue RNA - retina [nTPM]":"24.4","Tissue RNA - salivary gland [nTPM]":"11.9","Tissue RNA - seminal vesicle [nTPM]":"17.7","Tissue RNA - skeletal muscle [nTPM]":"35.9","Tissue RNA - skin 1 [nTPM]":"15.0","Tissue RNA - small intestine [nTPM]":"10.7","Tissue RNA - smooth muscle [nTPM]":"20.9","Tissue RNA - spinal cord [nTPM]":"24.9","Tissue RNA - spleen [nTPM]":"17.7","Tissue RNA - stomach 1 [nTPM]":"15.6","Tissue RNA - testis [nTPM]":"15.5","Tissue RNA - thalamus [nTPM]":"22.9","Tissue RNA - thymus [nTPM]":"18.6","Tissue RNA - thyroid gland [nTPM]":"24.3","Tissue RNA - tongue [nTPM]":"34.7","Tissue RNA - tonsil [nTPM]":"22.1","Tissue RNA - urinary bladder [nTPM]":"29.1","Tissue RNA - vagina [nTPM]":"12.7","Tissue RNA - white matter [nTPM]":"26.5","Cell RNA - A-431 [nTPM]":"28.6","Cell RNA - A549 [nTPM]":"12.8","Cell RNA - AF22 [nTPM]":"22.1","Cell RNA - AN3-CA [nTPM]":"19.7","Cell RNA - ASC diff [nTPM]":"47.7","Cell RNA - ASC TERT1 [nTPM]":"32.7","Cell RNA - BEWO [nTPM]":"32.4","Cell RNA - BJ [nTPM]":"26.6","Cell RNA - BJ hTERT+ [nTPM]":"47.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"35.8","Cell RNA - CACO-2 [nTPM]":"12.4","Cell RNA - CAPAN-2 [nTPM]":"16.0","Cell RNA - Daudi [nTPM]":"15.9","Cell RNA - EFO-21 [nTPM]":"33.1","Cell RNA - fHDF\/TERT166 [nTPM]":"26.4","Cell RNA - GAMG [nTPM]":"43.4","Cell RNA - HaCaT [nTPM]":"10.6","Cell RNA - HAP1 [nTPM]":"37.9","Cell RNA - HBEC3-KT [nTPM]":"17.1","Cell RNA - HBF TERT88 [nTPM]":"32.6","Cell RNA - HDLM-2 [nTPM]":"24.2","Cell RNA - HEK 293 [nTPM]":"10.1","Cell RNA - HEL [nTPM]":"11.0","Cell RNA - HeLa [nTPM]":"19.3","Cell RNA - Hep G2 [nTPM]":"9.1","Cell RNA - HHSteC [nTPM]":"34.8","Cell RNA - HL-60 [nTPM]":"7.6","Cell RNA - HMC-1 [nTPM]":"21.7","Cell RNA - HSkMC [nTPM]":"29.8","Cell RNA - hTCEpi [nTPM]":"31.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"29.2","Cell RNA - hTERT-HME1 [nTPM]":"26.9","Cell RNA - hTERT-RPE1 [nTPM]":"23.4","Cell RNA - HUVEC TERT2 [nTPM]":"29.5","Cell RNA - JURKAT [nTPM]":"17.7","Cell RNA - K-562 [nTPM]":"13.0","Cell RNA - Karpas-707 [nTPM]":"44.5","Cell RNA - LHCN-M2 [nTPM]":"27.2","Cell RNA - MCF7 [nTPM]":"18.9","Cell RNA - MOLT-4 [nTPM]":"18.0","Cell RNA - NB-4 [nTPM]":"18.3","Cell RNA - NTERA-2 [nTPM]":"9.8","Cell RNA - OE19 [nTPM]":"17.9","Cell RNA - PC-3 [nTPM]":"17.8","Cell RNA - REH [nTPM]":"6.5","Cell RNA - RH-30 [nTPM]":"23.3","Cell RNA - RPMI-8226 [nTPM]":"34.3","Cell RNA - RPTEC TERT1 [nTPM]":"25.9","Cell RNA - RT4 [nTPM]":"35.9","Cell RNA - SCLC-21H [nTPM]":"18.3","Cell RNA - SH-SY5Y [nTPM]":"25.3","Cell RNA - SiHa [nTPM]":"25.8","Cell RNA - SK-BR-3 [nTPM]":"27.4","Cell RNA - SK-MEL-30 [nTPM]":"32.7","Cell RNA - SuSa [nTPM]":"27.7","Cell RNA - T-47d [nTPM]":"11.6","Cell RNA - THP-1 [nTPM]":"12.6","Cell RNA - TIME [nTPM]":"24.2","Cell RNA - U-138 MG [nTPM]":"35.1","Cell RNA - U-2 OS [nTPM]":"15.7","Cell RNA - U-2197 [nTPM]":"52.8","Cell RNA - U-251 MG [nTPM]":"15.0","Cell RNA - U-266\/70 [nTPM]":"37.4","Cell RNA - U-266\/84 [nTPM]":"41.5","Cell RNA - U-698 [nTPM]":"23.9","Cell RNA - U-87 MG [nTPM]":"33.4","Cell RNA - U-937 [nTPM]":"11.4","Cell RNA - WM-115 [nTPM]":"23.2","Blood RNA - basophil [nTPM]":"21.9","Blood RNA - classical monocyte [nTPM]":"29.8","Blood RNA - eosinophil [nTPM]":"26.2","Blood RNA - gdT-cell [nTPM]":"14.6","Blood RNA - intermediate monocyte [nTPM]":"32.8","Blood RNA - MAIT T-cell [nTPM]":"17.8","Blood RNA - memory B-cell [nTPM]":"28.6","Blood RNA - memory CD4 T-cell [nTPM]":"14.2","Blood RNA - memory CD8 T-cell [nTPM]":"14.6","Blood RNA - myeloid DC [nTPM]":"29.2","Blood RNA - naive B-cell [nTPM]":"27.3","Blood RNA - naive CD4 T-cell [nTPM]":"15.4","Blood RNA - naive CD8 T-cell [nTPM]":"14.7","Blood RNA - neutrophil [nTPM]":"24.5","Blood RNA - NK-cell [nTPM]":"22.9","Blood RNA - non-classical monocyte [nTPM]":"43.4","Blood RNA - plasmacytoid DC [nTPM]":"11.6","Blood RNA - T-reg [nTPM]":"19.1","Blood RNA - total PBMC [nTPM]":"22.9","Brain RNA - amygdala [nTPM]":"23.6","Brain RNA - basal ganglia [nTPM]":"25.1","Brain RNA - cerebellum [nTPM]":"21.6","Brain RNA - cerebral cortex [nTPM]":"29.6","Brain RNA - hippocampal formation [nTPM]":"24.0","Brain RNA - hypothalamus [nTPM]":"26.5","Brain RNA - medulla oblongata [nTPM]":"23.5","Brain RNA - midbrain [nTPM]":"23.3","Brain RNA - pons [nTPM]":"23.4","Brain RNA - spinal cord [nTPM]":"24.9","Brain RNA - thalamus [nTPM]":"22.9","Brain RNA - white matter [nTPM]":"26.5","Single Cell Type RNA - Adipocytes [nTPM]":"64.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"49.3","Single Cell Type RNA - Astrocytes [nTPM]":"66.3","Single Cell Type RNA - B-cells [nTPM]":"91.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"92.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"124.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"42.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"55.2","Single Cell Type RNA - Bipolar cells [nTPM]":"64.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"45.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"35.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"49.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"51.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"58.0","Single Cell Type RNA - dendritic cells [nTPM]":"72.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"93.9","Single Cell Type RNA - Ductal cells [nTPM]":"32.0","Single Cell Type RNA - Early spermatids [nTPM]":"52.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"124.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"67.3","Single Cell Type RNA - Endothelial cells [nTPM]":"57.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"57.1","Single Cell Type RNA - Erythroid cells [nTPM]":"50.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"42.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"37.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"37.5","Single Cell Type RNA - Fibroblasts [nTPM]":"76.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"45.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"236.1","Single Cell Type RNA - granulocytes [nTPM]":"71.7","Single Cell Type RNA - Granulosa cells [nTPM]":"19.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.2","Single Cell Type RNA - Hepatocytes [nTPM]":"44.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"32.2","Single Cell Type RNA - Horizontal cells [nTPM]":"32.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"42.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"27.8","Single Cell Type RNA - Ionocytes [nTPM]":"67.1","Single Cell Type RNA - Kupffer cells [nTPM]":"45.5","Single Cell Type RNA - Langerhans cells [nTPM]":"90.0","Single Cell Type RNA - Late spermatids [nTPM]":"47.4","Single Cell Type RNA - Leydig cells [nTPM]":"32.0","Single Cell Type RNA - Macrophages [nTPM]":"113.8","Single Cell Type RNA - Melanocytes [nTPM]":"55.2","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"43.5","Single Cell Type RNA - Muller glia cells [nTPM]":"42.9","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"38.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"41.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.6","Single Cell Type RNA - Paneth cells [nTPM]":"38.6","Single Cell Type RNA - Peritubular cells [nTPM]":"39.5","Single Cell Type RNA - Plasma cells [nTPM]":"76.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"80.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"16.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"41.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"62.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"32.5","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"88.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"63.9","Single Cell Type RNA - Spermatocytes [nTPM]":"18.6","Single Cell Type RNA - Spermatogonia [nTPM]":"23.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"60.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"135.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"130.2","Single Cell Type RNA - T-cells [nTPM]":"69.1","Single Cell Type RNA - Theca cells [nTPM]":"43.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"22.9","Single Cell Type RNA - Urothelial cells [nTPM]":"122.7"},{"Gene":"PNPO","Gene synonym":["PDXPO"],"Ensembl":"ENSG00000108439","Gene description":"Pyridoxamine 5'-phosphate oxidase","Uniprot":["Q9NVS9"],"Chromosome":"17","Position":"47941506-47949308","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Pyridoxine biosynthesis"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"88.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"62.6","Hepatocytes":"53.4","Proximal tubular cells":"86.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023204","HPA027776"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"450000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA023204":"AB_1855506","HPA027776":"AB_10601246"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.47e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.3","Tissue RNA - adrenal gland [nTPM]":"15.8","Tissue RNA - amygdala [nTPM]":"16.5","Tissue RNA - appendix [nTPM]":"6.2","Tissue RNA - basal ganglia [nTPM]":"15.9","Tissue RNA - bone marrow [nTPM]":"3.5","Tissue RNA - breast [nTPM]":"10.6","Tissue RNA - cerebellum [nTPM]":"16.7","Tissue RNA - cerebral cortex [nTPM]":"22.0","Tissue RNA - cervix [nTPM]":"7.0","Tissue RNA - choroid plexus [nTPM]":"12.9","Tissue RNA - colon [nTPM]":"8.8","Tissue RNA - duodenum [nTPM]":"10.2","Tissue RNA - endometrium 1 [nTPM]":"5.0","Tissue RNA - epididymis [nTPM]":"11.6","Tissue RNA - esophagus [nTPM]":"10.7","Tissue RNA - fallopian tube [nTPM]":"10.1","Tissue RNA - gallbladder [nTPM]":"6.6","Tissue RNA - heart muscle [nTPM]":"13.2","Tissue RNA - hippocampal formation [nTPM]":"16.0","Tissue RNA - hypothalamus [nTPM]":"21.9","Tissue RNA - kidney [nTPM]":"35.1","Tissue RNA - liver [nTPM]":"88.8","Tissue RNA - lung [nTPM]":"6.4","Tissue RNA - lymph node [nTPM]":"6.9","Tissue RNA - medulla oblongata [nTPM]":"19.1","Tissue RNA - midbrain [nTPM]":"21.2","Tissue RNA - ovary [nTPM]":"5.8","Tissue RNA - pancreas [nTPM]":"10.9","Tissue RNA - parathyroid gland [nTPM]":"26.6","Tissue RNA - pituitary gland [nTPM]":"9.2","Tissue RNA - placenta [nTPM]":"7.0","Tissue RNA - pons [nTPM]":"20.6","Tissue RNA - prostate [nTPM]":"8.0","Tissue RNA - rectum [nTPM]":"8.6","Tissue RNA - retina [nTPM]":"5.4","Tissue RNA - salivary gland [nTPM]":"10.4","Tissue RNA - seminal vesicle [nTPM]":"7.8","Tissue RNA - skeletal muscle [nTPM]":"21.1","Tissue RNA - skin 1 [nTPM]":"6.7","Tissue RNA - small intestine [nTPM]":"9.6","Tissue RNA - smooth muscle [nTPM]":"6.1","Tissue RNA - spinal cord [nTPM]":"16.5","Tissue RNA - spleen [nTPM]":"7.2","Tissue RNA - stomach 1 [nTPM]":"8.6","Tissue RNA - testis [nTPM]":"6.6","Tissue RNA - thalamus [nTPM]":"20.6","Tissue RNA - thymus [nTPM]":"5.8","Tissue RNA - thyroid gland [nTPM]":"17.8","Tissue RNA - tongue [nTPM]":"19.6","Tissue RNA - tonsil [nTPM]":"7.7","Tissue RNA - urinary bladder [nTPM]":"6.7","Tissue RNA - vagina [nTPM]":"7.3","Tissue RNA - white matter [nTPM]":"14.3","Cell RNA - A-431 [nTPM]":"37.9","Cell RNA - A549 [nTPM]":"30.9","Cell RNA - AF22 [nTPM]":"2.4","Cell RNA - AN3-CA [nTPM]":"5.8","Cell RNA - ASC diff [nTPM]":"15.3","Cell RNA - ASC TERT1 [nTPM]":"11.7","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"12.2","Cell RNA - BJ hTERT+ [nTPM]":"7.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.9","Cell RNA - CACO-2 [nTPM]":"51.1","Cell RNA - CAPAN-2 [nTPM]":"27.6","Cell RNA - Daudi [nTPM]":"35.2","Cell RNA - EFO-21 [nTPM]":"57.4","Cell RNA - fHDF\/TERT166 [nTPM]":"12.7","Cell RNA - GAMG [nTPM]":"5.5","Cell RNA - HaCaT [nTPM]":"22.0","Cell RNA - HAP1 [nTPM]":"19.4","Cell RNA - HBEC3-KT [nTPM]":"34.7","Cell RNA - HBF TERT88 [nTPM]":"20.3","Cell RNA - HDLM-2 [nTPM]":"43.4","Cell RNA - HEK 293 [nTPM]":"16.4","Cell RNA - HEL [nTPM]":"24.6","Cell RNA - HeLa [nTPM]":"13.9","Cell RNA - Hep G2 [nTPM]":"53.6","Cell RNA - HHSteC [nTPM]":"16.3","Cell RNA - HL-60 [nTPM]":"22.6","Cell RNA - HMC-1 [nTPM]":"16.6","Cell RNA - HSkMC [nTPM]":"15.4","Cell RNA - hTCEpi [nTPM]":"26.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.8","Cell RNA - hTERT-HME1 [nTPM]":"32.7","Cell RNA - hTERT-RPE1 [nTPM]":"13.1","Cell RNA - HUVEC TERT2 [nTPM]":"18.0","Cell RNA - JURKAT [nTPM]":"26.1","Cell RNA - K-562 [nTPM]":"24.4","Cell RNA - Karpas-707 [nTPM]":"12.2","Cell RNA - LHCN-M2 [nTPM]":"16.5","Cell RNA - MCF7 [nTPM]":"28.3","Cell RNA - MOLT-4 [nTPM]":"25.3","Cell RNA - NB-4 [nTPM]":"7.8","Cell RNA - NTERA-2 [nTPM]":"4.5","Cell RNA - OE19 [nTPM]":"37.4","Cell RNA - PC-3 [nTPM]":"37.1","Cell RNA - REH [nTPM]":"18.8","Cell RNA - RH-30 [nTPM]":"10.4","Cell RNA - RPMI-8226 [nTPM]":"26.2","Cell RNA - RPTEC TERT1 [nTPM]":"40.2","Cell RNA - RT4 [nTPM]":"19.5","Cell RNA - SCLC-21H [nTPM]":"12.1","Cell RNA - SH-SY5Y [nTPM]":"9.5","Cell RNA - SiHa [nTPM]":"11.2","Cell RNA - SK-BR-3 [nTPM]":"18.6","Cell RNA - SK-MEL-30 [nTPM]":"10.7","Cell RNA - SuSa [nTPM]":"8.5","Cell RNA - T-47d [nTPM]":"32.4","Cell RNA - THP-1 [nTPM]":"9.1","Cell RNA - TIME [nTPM]":"19.1","Cell RNA - U-138 MG [nTPM]":"22.6","Cell RNA - U-2 OS [nTPM]":"12.8","Cell RNA - U-2197 [nTPM]":"22.2","Cell RNA - U-251 MG [nTPM]":"26.2","Cell RNA - U-266\/70 [nTPM]":"27.8","Cell RNA - U-266\/84 [nTPM]":"34.0","Cell RNA - U-698 [nTPM]":"19.0","Cell RNA - U-87 MG [nTPM]":"18.4","Cell RNA - U-937 [nTPM]":"19.2","Cell RNA - WM-115 [nTPM]":"11.7","Blood RNA - basophil [nTPM]":"2.5","Blood RNA - classical monocyte [nTPM]":"12.3","Blood RNA - eosinophil [nTPM]":"2.8","Blood RNA - gdT-cell [nTPM]":"7.2","Blood RNA - intermediate monocyte [nTPM]":"17.7","Blood RNA - MAIT T-cell [nTPM]":"8.2","Blood RNA - memory B-cell [nTPM]":"6.7","Blood RNA - memory CD4 T-cell [nTPM]":"6.3","Blood RNA - memory CD8 T-cell [nTPM]":"7.6","Blood RNA - myeloid DC [nTPM]":"13.5","Blood RNA - naive B-cell [nTPM]":"5.3","Blood RNA - naive CD4 T-cell [nTPM]":"8.2","Blood RNA - naive CD8 T-cell [nTPM]":"8.1","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"7.9","Blood RNA - non-classical monocyte [nTPM]":"11.9","Blood RNA - plasmacytoid DC [nTPM]":"9.8","Blood RNA - T-reg [nTPM]":"7.0","Blood RNA - total PBMC [nTPM]":"10.3","Brain RNA - amygdala [nTPM]":"16.5","Brain RNA - basal ganglia [nTPM]":"15.9","Brain RNA - cerebellum [nTPM]":"16.7","Brain RNA - cerebral cortex [nTPM]":"22.0","Brain RNA - hippocampal formation [nTPM]":"16.0","Brain RNA - hypothalamus [nTPM]":"21.9","Brain RNA - medulla oblongata [nTPM]":"19.1","Brain RNA - midbrain [nTPM]":"21.2","Brain RNA - pons [nTPM]":"20.6","Brain RNA - spinal cord [nTPM]":"16.5","Brain RNA - thalamus [nTPM]":"20.6","Brain RNA - white matter [nTPM]":"14.3","Single Cell Type RNA - Adipocytes [nTPM]":"7.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.9","Single Cell Type RNA - Astrocytes [nTPM]":"7.5","Single Cell Type RNA - B-cells [nTPM]":"3.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"1.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"6.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.4","Single Cell Type RNA - dendritic cells [nTPM]":"7.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"62.6","Single Cell Type RNA - Ductal cells [nTPM]":"18.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.4","Single Cell Type RNA - Endothelial cells [nTPM]":"5.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.9","Single Cell Type RNA - Fibroblasts [nTPM]":"5.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.3","Single Cell Type RNA - granulocytes [nTPM]":"12.7","Single Cell Type RNA - Granulosa cells [nTPM]":"8.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"53.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.2","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.6","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"11.4","Single Cell Type RNA - Langerhans cells [nTPM]":"2.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"9.9","Single Cell Type RNA - Macrophages [nTPM]":"10.6","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"8.6","Single Cell Type RNA - Muller glia cells [nTPM]":"7.1","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.0","Single Cell Type RNA - Paneth cells [nTPM]":"8.9","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"4.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"86.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.3","Single Cell Type RNA - T-cells [nTPM]":"4.7","Single Cell Type RNA - Theca cells [nTPM]":"19.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.4","Single Cell Type RNA - Urothelial cells [nTPM]":"5.0"},{"Gene":"PNPT1","Gene synonym":["DFNB70","old-35","OLD35","PNPase"],"Ensembl":"ENSG00000138035","Gene description":"Polyribonucleotide nucleotidyltransferase 1","Uniprot":["Q8TCS8"],"Chromosome":"2","Position":"55634061-55693863","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["mRNA processing","Transport"],"Molecular function":["Exonuclease","Hydrolase","Nuclease","Nucleotidyltransferase","RNA-binding","Transferase"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033424","HPA034602","HPA034603"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 11: Alveolar cells - Smell perception","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB033424":"AB_2299801","HPA034602":"AB_2674243","HPA034603":"AB_10603130"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.57e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.95e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.44e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.7","Tissue RNA - adrenal gland [nTPM]":"5.9","Tissue RNA - amygdala [nTPM]":"5.4","Tissue RNA - appendix [nTPM]":"4.0","Tissue RNA - basal ganglia [nTPM]":"7.0","Tissue RNA - bone marrow [nTPM]":"7.4","Tissue RNA - breast [nTPM]":"5.7","Tissue RNA - cerebellum [nTPM]":"6.4","Tissue RNA - cerebral cortex [nTPM]":"7.7","Tissue RNA - cervix [nTPM]":"5.2","Tissue RNA - choroid plexus [nTPM]":"6.4","Tissue RNA - colon [nTPM]":"5.7","Tissue RNA - duodenum [nTPM]":"3.3","Tissue RNA - endometrium 1 [nTPM]":"6.4","Tissue RNA - epididymis [nTPM]":"4.5","Tissue RNA - esophagus [nTPM]":"4.6","Tissue RNA - fallopian tube [nTPM]":"5.7","Tissue RNA - gallbladder [nTPM]":"3.0","Tissue RNA - heart muscle [nTPM]":"6.6","Tissue RNA - hippocampal formation [nTPM]":"4.8","Tissue RNA - hypothalamus [nTPM]":"6.5","Tissue RNA - kidney [nTPM]":"5.6","Tissue RNA - liver [nTPM]":"5.2","Tissue RNA - lung [nTPM]":"5.0","Tissue RNA - lymph node [nTPM]":"4.3","Tissue RNA - medulla oblongata [nTPM]":"6.9","Tissue RNA - midbrain [nTPM]":"6.0","Tissue RNA - ovary [nTPM]":"4.8","Tissue RNA - pancreas [nTPM]":"7.8","Tissue RNA - parathyroid gland [nTPM]":"4.9","Tissue RNA - pituitary gland [nTPM]":"5.0","Tissue RNA - placenta [nTPM]":"2.9","Tissue RNA - pons [nTPM]":"7.1","Tissue RNA - prostate [nTPM]":"4.4","Tissue RNA - rectum [nTPM]":"5.2","Tissue RNA - retina [nTPM]":"5.5","Tissue RNA - salivary gland [nTPM]":"5.0","Tissue RNA - seminal vesicle [nTPM]":"3.2","Tissue RNA - skeletal muscle [nTPM]":"11.5","Tissue RNA - skin 1 [nTPM]":"5.9","Tissue RNA - small intestine [nTPM]":"5.3","Tissue RNA - smooth muscle [nTPM]":"4.2","Tissue RNA - spinal cord [nTPM]":"5.7","Tissue RNA - spleen [nTPM]":"6.2","Tissue RNA - stomach 1 [nTPM]":"5.8","Tissue RNA - testis [nTPM]":"3.2","Tissue RNA - thalamus [nTPM]":"6.3","Tissue RNA - thymus [nTPM]":"3.4","Tissue RNA - thyroid gland [nTPM]":"5.2","Tissue RNA - tongue [nTPM]":"5.9","Tissue RNA - tonsil [nTPM]":"3.3","Tissue RNA - urinary bladder [nTPM]":"5.6","Tissue RNA - vagina [nTPM]":"4.5","Tissue RNA - white matter [nTPM]":"9.0","Cell RNA - A-431 [nTPM]":"9.0","Cell RNA - A549 [nTPM]":"4.3","Cell RNA - AF22 [nTPM]":"6.5","Cell RNA - AN3-CA [nTPM]":"2.9","Cell RNA - ASC diff [nTPM]":"4.7","Cell RNA - ASC TERT1 [nTPM]":"7.8","Cell RNA - BEWO [nTPM]":"8.4","Cell RNA - BJ [nTPM]":"12.2","Cell RNA - BJ hTERT+ [nTPM]":"7.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.1","Cell RNA - CACO-2 [nTPM]":"13.5","Cell RNA - CAPAN-2 [nTPM]":"4.2","Cell RNA - Daudi [nTPM]":"17.9","Cell RNA - EFO-21 [nTPM]":"5.4","Cell RNA - fHDF\/TERT166 [nTPM]":"5.8","Cell RNA - GAMG [nTPM]":"6.2","Cell RNA - HaCaT [nTPM]":"7.1","Cell RNA - HAP1 [nTPM]":"8.3","Cell RNA - HBEC3-KT [nTPM]":"10.1","Cell RNA - HBF TERT88 [nTPM]":"9.5","Cell RNA - HDLM-2 [nTPM]":"6.3","Cell RNA - HEK 293 [nTPM]":"16.3","Cell RNA - HEL [nTPM]":"10.2","Cell RNA - HeLa [nTPM]":"5.9","Cell RNA - Hep G2 [nTPM]":"7.0","Cell RNA - HHSteC [nTPM]":"11.8","Cell RNA - HL-60 [nTPM]":"25.0","Cell RNA - HMC-1 [nTPM]":"6.4","Cell RNA - HSkMC [nTPM]":"8.6","Cell RNA - hTCEpi [nTPM]":"6.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.4","Cell RNA - hTERT-HME1 [nTPM]":"7.0","Cell RNA - hTERT-RPE1 [nTPM]":"4.7","Cell RNA - HUVEC TERT2 [nTPM]":"6.4","Cell RNA - JURKAT [nTPM]":"7.3","Cell RNA - K-562 [nTPM]":"11.5","Cell RNA - Karpas-707 [nTPM]":"4.2","Cell RNA - LHCN-M2 [nTPM]":"8.0","Cell RNA - MCF7 [nTPM]":"4.4","Cell RNA - MOLT-4 [nTPM]":"15.4","Cell RNA - NB-4 [nTPM]":"17.9","Cell RNA - NTERA-2 [nTPM]":"15.5","Cell RNA - OE19 [nTPM]":"9.3","Cell RNA - PC-3 [nTPM]":"8.1","Cell RNA - REH [nTPM]":"15.2","Cell RNA - RH-30 [nTPM]":"10.9","Cell RNA - RPMI-8226 [nTPM]":"16.6","Cell RNA - RPTEC TERT1 [nTPM]":"8.6","Cell RNA - RT4 [nTPM]":"5.2","Cell RNA - SCLC-21H [nTPM]":"15.2","Cell RNA - SH-SY5Y [nTPM]":"9.6","Cell RNA - SiHa [nTPM]":"4.4","Cell RNA - SK-BR-3 [nTPM]":"14.3","Cell RNA - SK-MEL-30 [nTPM]":"17.0","Cell RNA - SuSa [nTPM]":"5.6","Cell RNA - T-47d [nTPM]":"3.8","Cell RNA - THP-1 [nTPM]":"11.4","Cell RNA - TIME [nTPM]":"6.4","Cell RNA - U-138 MG [nTPM]":"4.6","Cell RNA - U-2 OS [nTPM]":"3.9","Cell RNA - U-2197 [nTPM]":"4.2","Cell RNA - U-251 MG [nTPM]":"13.5","Cell RNA - U-266\/70 [nTPM]":"18.9","Cell RNA - U-266\/84 [nTPM]":"1.3","Cell RNA - U-698 [nTPM]":"3.8","Cell RNA - U-87 MG [nTPM]":"9.2","Cell RNA - U-937 [nTPM]":"21.1","Cell RNA - WM-115 [nTPM]":"8.3","Blood RNA - basophil [nTPM]":"3.3","Blood RNA - classical monocyte [nTPM]":"3.4","Blood RNA - eosinophil [nTPM]":"4.0","Blood RNA - gdT-cell [nTPM]":"4.2","Blood RNA - intermediate monocyte [nTPM]":"2.8","Blood RNA - MAIT T-cell [nTPM]":"2.4","Blood RNA - memory B-cell [nTPM]":"3.1","Blood RNA - memory CD4 T-cell [nTPM]":"1.7","Blood RNA - memory CD8 T-cell [nTPM]":"4.1","Blood RNA - myeloid DC [nTPM]":"1.3","Blood RNA - naive B-cell [nTPM]":"5.6","Blood RNA - naive CD4 T-cell [nTPM]":"3.4","Blood RNA - naive CD8 T-cell [nTPM]":"3.9","Blood RNA - neutrophil [nTPM]":"3.4","Blood RNA - NK-cell [nTPM]":"2.2","Blood RNA - non-classical monocyte [nTPM]":"2.7","Blood RNA - plasmacytoid DC [nTPM]":"4.1","Blood RNA - T-reg [nTPM]":"1.4","Blood RNA - total PBMC [nTPM]":"2.9","Brain RNA - amygdala [nTPM]":"5.4","Brain RNA - basal ganglia [nTPM]":"7.0","Brain RNA - cerebellum [nTPM]":"6.4","Brain RNA - cerebral cortex [nTPM]":"7.7","Brain RNA - hippocampal formation [nTPM]":"4.8","Brain RNA - hypothalamus [nTPM]":"6.5","Brain RNA - medulla oblongata [nTPM]":"6.9","Brain RNA - midbrain [nTPM]":"6.0","Brain RNA - pons [nTPM]":"7.1","Brain RNA - spinal cord [nTPM]":"5.7","Brain RNA - thalamus [nTPM]":"6.3","Brain RNA - white matter [nTPM]":"9.0","Single Cell Type RNA - Adipocytes [nTPM]":"25.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"57.0","Single Cell Type RNA - Astrocytes [nTPM]":"23.8","Single Cell Type RNA - B-cells [nTPM]":"21.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"24.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"29.0","Single Cell Type RNA - Bipolar cells [nTPM]":"41.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"46.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"58.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.9","Single Cell Type RNA - dendritic cells [nTPM]":"14.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"18.6","Single Cell Type RNA - Early spermatids [nTPM]":"25.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"28.9","Single Cell Type RNA - Endothelial cells [nTPM]":"24.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.2","Single Cell Type RNA - Erythroid cells [nTPM]":"17.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"48.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"23.3","Single Cell Type RNA - Fibroblasts [nTPM]":"25.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.3","Single Cell Type RNA - granulocytes [nTPM]":"58.7","Single Cell Type RNA - Granulosa cells [nTPM]":"21.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"14.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.4","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"48.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.8","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"12.2","Single Cell Type RNA - Langerhans cells [nTPM]":"17.7","Single Cell Type RNA - Late spermatids [nTPM]":"4.8","Single Cell Type RNA - Leydig cells [nTPM]":"17.4","Single Cell Type RNA - Macrophages [nTPM]":"26.7","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"16.5","Single Cell Type RNA - Muller glia cells [nTPM]":"23.9","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"34.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"97.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.8","Single Cell Type RNA - Paneth cells [nTPM]":"11.4","Single Cell Type RNA - Peritubular cells [nTPM]":"18.4","Single Cell Type RNA - Plasma cells [nTPM]":"23.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"26.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"38.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"58.6","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"31.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.3","Single Cell Type RNA - Spermatocytes [nTPM]":"43.4","Single Cell Type RNA - Spermatogonia [nTPM]":"20.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.3","Single Cell Type RNA - T-cells [nTPM]":"24.7","Single Cell Type RNA - Theca cells [nTPM]":"58.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.6","Single Cell Type RNA - Urothelial cells [nTPM]":"17.6"},{"Gene":"POFUT1","Gene synonym":["FUT12","KIAA0180","O-Fuc-T","O-FUT"],"Ensembl":"ENSG00000101346","Gene description":"Protein O-fucosyltransferase 1","Uniprot":["Q9H488"],"Chromosome":"20","Position":"32207880-32238658","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism","Fucose metabolism","Notch signaling pathway"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"39.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"20.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"monocytes":"20.9"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054519","HPA059935"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"60000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA054519":"AB_2682515","HPA059935":"AB_2684171"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-3"},"Tissue RNA - adipose tissue [nTPM]":"17.6","Tissue RNA - adrenal gland [nTPM]":"10.8","Tissue RNA - amygdala [nTPM]":"7.9","Tissue RNA - appendix [nTPM]":"11.7","Tissue RNA - basal ganglia [nTPM]":"8.4","Tissue RNA - bone marrow [nTPM]":"10.5","Tissue RNA - breast [nTPM]":"16.5","Tissue RNA - cerebellum [nTPM]":"7.2","Tissue RNA - cerebral cortex [nTPM]":"7.7","Tissue RNA - cervix [nTPM]":"15.2","Tissue RNA - choroid plexus [nTPM]":"9.1","Tissue RNA - colon [nTPM]":"20.0","Tissue RNA - duodenum [nTPM]":"20.4","Tissue RNA - endometrium 1 [nTPM]":"14.9","Tissue RNA - epididymis [nTPM]":"14.4","Tissue RNA - esophagus [nTPM]":"12.4","Tissue RNA - fallopian tube [nTPM]":"20.4","Tissue RNA - gallbladder [nTPM]":"11.4","Tissue RNA - heart muscle [nTPM]":"17.5","Tissue RNA - hippocampal formation [nTPM]":"7.7","Tissue RNA - hypothalamus [nTPM]":"7.3","Tissue RNA - kidney [nTPM]":"16.1","Tissue RNA - liver [nTPM]":"30.9","Tissue RNA - lung [nTPM]":"12.2","Tissue RNA - lymph node [nTPM]":"9.1","Tissue RNA - medulla oblongata [nTPM]":"9.3","Tissue RNA - midbrain [nTPM]":"8.3","Tissue RNA - ovary [nTPM]":"20.0","Tissue RNA - pancreas [nTPM]":"13.8","Tissue RNA - parathyroid gland [nTPM]":"23.8","Tissue RNA - pituitary gland [nTPM]":"9.1","Tissue RNA - placenta [nTPM]":"16.4","Tissue RNA - pons [nTPM]":"8.0","Tissue RNA - prostate [nTPM]":"14.5","Tissue RNA - rectum [nTPM]":"19.1","Tissue RNA - retina [nTPM]":"5.9","Tissue RNA - salivary gland [nTPM]":"13.0","Tissue RNA - seminal vesicle [nTPM]":"18.1","Tissue RNA - skeletal muscle [nTPM]":"12.8","Tissue RNA - skin 1 [nTPM]":"13.7","Tissue RNA - small intestine [nTPM]":"24.0","Tissue RNA - smooth muscle [nTPM]":"18.1","Tissue RNA - spinal cord [nTPM]":"8.0","Tissue RNA - spleen [nTPM]":"9.4","Tissue RNA - stomach 1 [nTPM]":"11.1","Tissue RNA - testis [nTPM]":"9.5","Tissue RNA - thalamus [nTPM]":"8.1","Tissue RNA - thymus [nTPM]":"10.5","Tissue RNA - thyroid gland [nTPM]":"18.9","Tissue RNA - tongue [nTPM]":"14.0","Tissue RNA - tonsil [nTPM]":"10.0","Tissue RNA - urinary bladder [nTPM]":"14.0","Tissue RNA - vagina [nTPM]":"10.9","Tissue RNA - white matter [nTPM]":"8.2","Cell RNA - A-431 [nTPM]":"47.1","Cell RNA - A549 [nTPM]":"37.2","Cell RNA - AF22 [nTPM]":"31.5","Cell RNA - AN3-CA [nTPM]":"34.7","Cell RNA - ASC diff [nTPM]":"52.9","Cell RNA - ASC TERT1 [nTPM]":"51.4","Cell RNA - BEWO [nTPM]":"58.8","Cell RNA - BJ [nTPM]":"47.8","Cell RNA - BJ hTERT+ [nTPM]":"56.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"78.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"51.3","Cell RNA - CACO-2 [nTPM]":"111.9","Cell RNA - CAPAN-2 [nTPM]":"62.1","Cell RNA - Daudi [nTPM]":"31.7","Cell RNA - EFO-21 [nTPM]":"69.8","Cell RNA - fHDF\/TERT166 [nTPM]":"53.5","Cell RNA - GAMG [nTPM]":"87.2","Cell RNA - HaCaT [nTPM]":"51.2","Cell RNA - HAP1 [nTPM]":"30.5","Cell RNA - HBEC3-KT [nTPM]":"59.0","Cell RNA - HBF TERT88 [nTPM]":"68.0","Cell RNA - HDLM-2 [nTPM]":"16.5","Cell RNA - HEK 293 [nTPM]":"19.2","Cell RNA - HEL [nTPM]":"47.1","Cell RNA - HeLa [nTPM]":"32.1","Cell RNA - Hep G2 [nTPM]":"51.2","Cell RNA - HHSteC [nTPM]":"41.2","Cell RNA - HL-60 [nTPM]":"41.0","Cell RNA - HMC-1 [nTPM]":"28.9","Cell RNA - HSkMC [nTPM]":"45.4","Cell RNA - hTCEpi [nTPM]":"45.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"59.7","Cell RNA - hTERT-HME1 [nTPM]":"38.8","Cell RNA - hTERT-RPE1 [nTPM]":"33.5","Cell RNA - HUVEC TERT2 [nTPM]":"44.6","Cell RNA - JURKAT [nTPM]":"30.0","Cell RNA - K-562 [nTPM]":"36.3","Cell RNA - Karpas-707 [nTPM]":"17.6","Cell RNA - LHCN-M2 [nTPM]":"55.6","Cell RNA - MCF7 [nTPM]":"23.1","Cell RNA - MOLT-4 [nTPM]":"28.4","Cell RNA - NB-4 [nTPM]":"31.4","Cell RNA - NTERA-2 [nTPM]":"16.2","Cell RNA - OE19 [nTPM]":"45.2","Cell RNA - PC-3 [nTPM]":"59.4","Cell RNA - REH [nTPM]":"23.3","Cell RNA - RH-30 [nTPM]":"83.6","Cell RNA - RPMI-8226 [nTPM]":"29.5","Cell RNA - RPTEC TERT1 [nTPM]":"24.2","Cell RNA - RT4 [nTPM]":"30.7","Cell RNA - SCLC-21H [nTPM]":"20.6","Cell RNA - SH-SY5Y [nTPM]":"26.5","Cell RNA - SiHa [nTPM]":"109.5","Cell RNA - SK-BR-3 [nTPM]":"30.0","Cell RNA - SK-MEL-30 [nTPM]":"41.0","Cell RNA - SuSa [nTPM]":"24.0","Cell RNA - T-47d [nTPM]":"44.7","Cell RNA - THP-1 [nTPM]":"48.5","Cell RNA - TIME [nTPM]":"38.8","Cell RNA - U-138 MG [nTPM]":"113.4","Cell RNA - U-2 OS [nTPM]":"42.2","Cell RNA - U-2197 [nTPM]":"71.8","Cell RNA - U-251 MG [nTPM]":"82.4","Cell RNA - U-266\/70 [nTPM]":"21.4","Cell RNA - U-266\/84 [nTPM]":"29.3","Cell RNA - U-698 [nTPM]":"28.7","Cell RNA - U-87 MG [nTPM]":"68.5","Cell RNA - U-937 [nTPM]":"139.9","Cell RNA - WM-115 [nTPM]":"73.0","Blood RNA - basophil [nTPM]":"4.3","Blood RNA - classical monocyte [nTPM]":"5.4","Blood RNA - eosinophil [nTPM]":"2.6","Blood RNA - gdT-cell [nTPM]":"3.2","Blood RNA - intermediate monocyte [nTPM]":"15.1","Blood RNA - MAIT T-cell [nTPM]":"3.6","Blood RNA - memory B-cell [nTPM]":"3.2","Blood RNA - memory CD4 T-cell [nTPM]":"2.8","Blood RNA - memory CD8 T-cell [nTPM]":"3.0","Blood RNA - myeloid DC [nTPM]":"4.6","Blood RNA - naive B-cell [nTPM]":"2.6","Blood RNA - naive CD4 T-cell [nTPM]":"3.6","Blood RNA - naive CD8 T-cell [nTPM]":"2.5","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"2.0","Blood RNA - non-classical monocyte [nTPM]":"20.9","Blood RNA - plasmacytoid DC [nTPM]":"3.4","Blood RNA - T-reg [nTPM]":"3.3","Blood RNA - total PBMC [nTPM]":"4.2","Brain RNA - amygdala [nTPM]":"7.9","Brain RNA - basal ganglia [nTPM]":"8.4","Brain RNA - cerebellum [nTPM]":"7.2","Brain RNA - cerebral cortex [nTPM]":"7.7","Brain RNA - hippocampal formation [nTPM]":"7.7","Brain RNA - hypothalamus [nTPM]":"7.3","Brain RNA - medulla oblongata [nTPM]":"9.3","Brain RNA - midbrain [nTPM]":"8.3","Brain RNA - pons [nTPM]":"8.0","Brain RNA - spinal cord [nTPM]":"8.0","Brain RNA - thalamus [nTPM]":"8.1","Brain RNA - white matter [nTPM]":"8.2","Single Cell Type RNA - Adipocytes [nTPM]":"7.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.5","Single Cell Type RNA - Astrocytes [nTPM]":"11.1","Single Cell Type RNA - B-cells [nTPM]":"5.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"3.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"7.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.2","Single Cell Type RNA - dendritic cells [nTPM]":"5.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"10.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.8","Single Cell Type RNA - Endothelial cells [nTPM]":"9.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.0","Single Cell Type RNA - Erythroid cells [nTPM]":"9.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"28.2","Single Cell Type RNA - Fibroblasts [nTPM]":"12.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.6","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"13.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.9","Single Cell Type RNA - Hepatocytes [nTPM]":"39.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.7","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.4","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"8.1","Single Cell Type RNA - Langerhans cells [nTPM]":"3.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.7","Single Cell Type RNA - Leydig cells [nTPM]":"10.5","Single Cell Type RNA - Macrophages [nTPM]":"6.5","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"9.3","Single Cell Type RNA - Muller glia cells [nTPM]":"5.2","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.6","Single Cell Type RNA - Paneth cells [nTPM]":"11.9","Single Cell Type RNA - Peritubular cells [nTPM]":"14.3","Single Cell Type RNA - Plasma cells [nTPM]":"8.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"31.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.3","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.4","Single Cell Type RNA - Spermatocytes [nTPM]":"2.9","Single Cell Type RNA - Spermatogonia [nTPM]":"7.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.7","Single Cell Type RNA - T-cells [nTPM]":"5.0","Single Cell Type RNA - Theca cells [nTPM]":"26.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.0","Single Cell Type RNA - Urothelial cells [nTPM]":"4.1"},{"Gene":"POGLUT1","Gene synonym":["9630046K23Rik","C3orf9","hCLP46","KDELCL1","KTELC1","MDS010","MDSRP","MGC32995","Rumi"],"Ensembl":"ENSG00000163389","Gene description":"Protein O-glucosyltransferase 1","Uniprot":["Q8NBL1"],"Chromosome":"3","Position":"119468963-119494708","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Gastrulation"],"Molecular function":["Developmental protein","Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant","Limb-girdle muscular dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"81.2","monocytes":"151.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037855","HPA037856"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 3: Monocytes - Immune response regulation","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA037855":"AB_10672728","HPA037856":"AB_2732477"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.02e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.23e-4"},"Tissue RNA - adipose tissue [nTPM]":"6.8","Tissue RNA - adrenal gland [nTPM]":"7.2","Tissue RNA - amygdala [nTPM]":"5.9","Tissue RNA - appendix [nTPM]":"7.8","Tissue RNA - basal ganglia [nTPM]":"6.1","Tissue RNA - bone marrow [nTPM]":"3.1","Tissue RNA - breast [nTPM]":"7.7","Tissue RNA - cerebellum [nTPM]":"6.0","Tissue RNA - cerebral cortex [nTPM]":"8.2","Tissue RNA - cervix [nTPM]":"7.1","Tissue RNA - choroid plexus [nTPM]":"6.9","Tissue RNA - colon [nTPM]":"6.8","Tissue RNA - duodenum [nTPM]":"4.2","Tissue RNA - endometrium 1 [nTPM]":"9.0","Tissue RNA - epididymis [nTPM]":"7.8","Tissue RNA - esophagus [nTPM]":"5.6","Tissue RNA - fallopian tube [nTPM]":"6.0","Tissue RNA - gallbladder [nTPM]":"4.7","Tissue RNA - heart muscle [nTPM]":"5.9","Tissue RNA - hippocampal formation [nTPM]":"5.9","Tissue RNA - hypothalamus [nTPM]":"7.2","Tissue RNA - kidney [nTPM]":"5.7","Tissue RNA - liver [nTPM]":"6.6","Tissue RNA - lung [nTPM]":"5.6","Tissue RNA - lymph node [nTPM]":"10.8","Tissue RNA - medulla oblongata [nTPM]":"6.6","Tissue RNA - midbrain [nTPM]":"6.5","Tissue RNA - ovary [nTPM]":"5.5","Tissue RNA - pancreas [nTPM]":"7.9","Tissue RNA - parathyroid gland [nTPM]":"9.5","Tissue RNA - pituitary gland [nTPM]":"4.9","Tissue RNA - placenta [nTPM]":"8.2","Tissue RNA - pons [nTPM]":"6.6","Tissue RNA - prostate [nTPM]":"5.4","Tissue RNA - rectum [nTPM]":"7.2","Tissue RNA - retina [nTPM]":"4.2","Tissue RNA - salivary gland [nTPM]":"4.6","Tissue RNA - seminal vesicle [nTPM]":"11.6","Tissue RNA - skeletal muscle [nTPM]":"3.2","Tissue RNA - skin 1 [nTPM]":"10.0","Tissue RNA - small intestine [nTPM]":"7.8","Tissue RNA - smooth muscle [nTPM]":"10.4","Tissue RNA - spinal cord [nTPM]":"6.1","Tissue RNA - spleen [nTPM]":"9.0","Tissue RNA - stomach 1 [nTPM]":"5.4","Tissue RNA - testis [nTPM]":"2.5","Tissue RNA - thalamus [nTPM]":"7.2","Tissue RNA - thymus [nTPM]":"9.7","Tissue RNA - thyroid gland [nTPM]":"5.6","Tissue RNA - tongue [nTPM]":"3.4","Tissue RNA - tonsil [nTPM]":"10.8","Tissue RNA - urinary bladder [nTPM]":"8.5","Tissue RNA - vagina [nTPM]":"6.3","Tissue RNA - white matter [nTPM]":"6.7","Cell RNA - A-431 [nTPM]":"10.8","Cell RNA - A549 [nTPM]":"7.1","Cell RNA - AF22 [nTPM]":"11.7","Cell RNA - AN3-CA [nTPM]":"13.1","Cell RNA - ASC diff [nTPM]":"29.5","Cell RNA - ASC TERT1 [nTPM]":"16.8","Cell RNA - BEWO [nTPM]":"8.6","Cell RNA - BJ [nTPM]":"16.7","Cell RNA - BJ hTERT+ [nTPM]":"16.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"18.4","Cell RNA - CACO-2 [nTPM]":"11.5","Cell RNA - CAPAN-2 [nTPM]":"6.9","Cell RNA - Daudi [nTPM]":"16.5","Cell RNA - EFO-21 [nTPM]":"22.2","Cell RNA - fHDF\/TERT166 [nTPM]":"21.4","Cell RNA - GAMG [nTPM]":"10.6","Cell RNA - HaCaT [nTPM]":"11.9","Cell RNA - HAP1 [nTPM]":"15.9","Cell RNA - HBEC3-KT [nTPM]":"16.8","Cell RNA - HBF TERT88 [nTPM]":"20.4","Cell RNA - HDLM-2 [nTPM]":"14.4","Cell RNA - HEK 293 [nTPM]":"10.6","Cell RNA - HEL [nTPM]":"19.3","Cell RNA - HeLa [nTPM]":"11.1","Cell RNA - Hep G2 [nTPM]":"12.9","Cell RNA - HHSteC [nTPM]":"19.1","Cell RNA - HL-60 [nTPM]":"21.3","Cell RNA - HMC-1 [nTPM]":"21.7","Cell RNA - HSkMC [nTPM]":"17.5","Cell RNA - hTCEpi [nTPM]":"9.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.3","Cell RNA - hTERT-HME1 [nTPM]":"18.0","Cell RNA - hTERT-RPE1 [nTPM]":"15.7","Cell RNA - HUVEC TERT2 [nTPM]":"15.5","Cell RNA - JURKAT [nTPM]":"11.2","Cell RNA - K-562 [nTPM]":"10.5","Cell RNA - Karpas-707 [nTPM]":"19.7","Cell RNA - LHCN-M2 [nTPM]":"13.9","Cell RNA - MCF7 [nTPM]":"10.9","Cell RNA - MOLT-4 [nTPM]":"12.5","Cell RNA - NB-4 [nTPM]":"20.7","Cell RNA - NTERA-2 [nTPM]":"12.4","Cell RNA - OE19 [nTPM]":"18.6","Cell RNA - PC-3 [nTPM]":"13.8","Cell RNA - REH [nTPM]":"12.2","Cell RNA - RH-30 [nTPM]":"12.2","Cell RNA - RPMI-8226 [nTPM]":"24.0","Cell RNA - RPTEC TERT1 [nTPM]":"11.6","Cell RNA - RT4 [nTPM]":"13.9","Cell RNA - SCLC-21H [nTPM]":"12.7","Cell RNA - SH-SY5Y [nTPM]":"20.0","Cell RNA - SiHa [nTPM]":"8.1","Cell RNA - SK-BR-3 [nTPM]":"4.9","Cell RNA - SK-MEL-30 [nTPM]":"13.4","Cell RNA - SuSa [nTPM]":"11.7","Cell RNA - T-47d [nTPM]":"13.2","Cell RNA - THP-1 [nTPM]":"17.8","Cell RNA - TIME [nTPM]":"19.7","Cell RNA - U-138 MG [nTPM]":"13.1","Cell RNA - U-2 OS [nTPM]":"8.0","Cell RNA - U-2197 [nTPM]":"3.8","Cell RNA - U-251 MG [nTPM]":"8.9","Cell RNA - U-266\/70 [nTPM]":"27.1","Cell RNA - U-266\/84 [nTPM]":"25.2","Cell RNA - U-698 [nTPM]":"21.7","Cell RNA - U-87 MG [nTPM]":"11.1","Cell RNA - U-937 [nTPM]":"20.6","Cell RNA - WM-115 [nTPM]":"18.8","Blood RNA - basophil [nTPM]":"2.9","Blood RNA - classical monocyte [nTPM]":"16.4","Blood RNA - eosinophil [nTPM]":"13.9","Blood RNA - gdT-cell [nTPM]":"16.2","Blood RNA - intermediate monocyte [nTPM]":"15.7","Blood RNA - MAIT T-cell [nTPM]":"18.7","Blood RNA - memory B-cell [nTPM]":"13.9","Blood RNA - memory CD4 T-cell [nTPM]":"18.2","Blood RNA - memory CD8 T-cell [nTPM]":"17.0","Blood RNA - myeloid DC [nTPM]":"20.7","Blood RNA - naive B-cell [nTPM]":"10.1","Blood RNA - naive CD4 T-cell [nTPM]":"21.1","Blood RNA - naive CD8 T-cell [nTPM]":"20.0","Blood RNA - neutrophil [nTPM]":"1.2","Blood RNA - NK-cell [nTPM]":"29.5","Blood RNA - non-classical monocyte [nTPM]":"10.8","Blood RNA - plasmacytoid DC [nTPM]":"11.5","Blood RNA - T-reg [nTPM]":"22.3","Blood RNA - total PBMC [nTPM]":"15.0","Brain RNA - amygdala [nTPM]":"5.9","Brain RNA - basal ganglia [nTPM]":"6.1","Brain RNA - cerebellum [nTPM]":"6.0","Brain RNA - cerebral cortex [nTPM]":"8.2","Brain RNA - hippocampal formation [nTPM]":"5.9","Brain RNA - hypothalamus [nTPM]":"7.2","Brain RNA - medulla oblongata [nTPM]":"6.6","Brain RNA - midbrain [nTPM]":"6.5","Brain RNA - pons [nTPM]":"6.6","Brain RNA - spinal cord [nTPM]":"6.1","Brain RNA - thalamus [nTPM]":"7.2","Brain RNA - white matter [nTPM]":"6.7","Single Cell Type RNA - Adipocytes [nTPM]":"19.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.2","Single Cell Type RNA - Astrocytes [nTPM]":"11.4","Single Cell Type RNA - B-cells [nTPM]":"15.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"16.5","Single Cell Type RNA - Bipolar cells [nTPM]":"13.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"10.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.6","Single Cell Type RNA - dendritic cells [nTPM]":"17.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.3","Single Cell Type RNA - Endothelial cells [nTPM]":"16.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.5","Single Cell Type RNA - Erythroid cells [nTPM]":"8.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"32.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.7","Single Cell Type RNA - Fibroblasts [nTPM]":"14.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.0","Single Cell Type RNA - granulocytes [nTPM]":"17.7","Single Cell Type RNA - Granulosa cells [nTPM]":"11.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"12.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.4","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"31.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.7","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"11.9","Single Cell Type RNA - Langerhans cells [nTPM]":"81.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"8.7","Single Cell Type RNA - Macrophages [nTPM]":"16.6","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"151.4","Single Cell Type RNA - Muller glia cells [nTPM]":"10.3","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"23.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"25.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.0","Single Cell Type RNA - Paneth cells [nTPM]":"8.3","Single Cell Type RNA - Peritubular cells [nTPM]":"17.0","Single Cell Type RNA - Plasma cells [nTPM]":"14.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.4","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.6","Single Cell Type RNA - T-cells [nTPM]":"15.5","Single Cell Type RNA - Theca cells [nTPM]":"17.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.9","Single Cell Type RNA - Urothelial cells [nTPM]":"5.9"},{"Gene":"POLD1","Gene synonym":["CDC2","POLD"],"Ensembl":"ENSG00000062822","Gene description":"DNA polymerase delta 1, catalytic subunit","Uniprot":["P28340"],"Chromosome":"19","Position":"50384204-50418018","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA excision","DNA repair","DNA replication"],"Molecular function":["DNA-binding","DNA-directed DNA polymerase","Exonuclease","Hydrolase","Nuclease","Nucleotidyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Paneth cells":"51.3","Spermatogonia":"25.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004375","HPA046524"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB004375":"AB_675487","HPA046524":"AB_2679684"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.87e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.6","Tissue RNA - adrenal gland [nTPM]":"5.1","Tissue RNA - amygdala [nTPM]":"3.2","Tissue RNA - appendix [nTPM]":"9.2","Tissue RNA - basal ganglia [nTPM]":"3.7","Tissue RNA - bone marrow [nTPM]":"26.3","Tissue RNA - breast [nTPM]":"6.3","Tissue RNA - cerebellum [nTPM]":"4.5","Tissue RNA - cerebral cortex [nTPM]":"3.8","Tissue RNA - cervix [nTPM]":"7.6","Tissue RNA - choroid plexus [nTPM]":"2.5","Tissue RNA - colon [nTPM]":"8.9","Tissue RNA - duodenum [nTPM]":"5.4","Tissue RNA - endometrium 1 [nTPM]":"8.4","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"10.7","Tissue RNA - fallopian tube [nTPM]":"6.5","Tissue RNA - gallbladder [nTPM]":"2.1","Tissue RNA - heart muscle [nTPM]":"5.8","Tissue RNA - hippocampal formation [nTPM]":"2.7","Tissue RNA - hypothalamus [nTPM]":"2.7","Tissue RNA - kidney [nTPM]":"6.5","Tissue RNA - liver [nTPM]":"6.4","Tissue RNA - lung [nTPM]":"9.5","Tissue RNA - lymph node [nTPM]":"11.2","Tissue RNA - medulla oblongata [nTPM]":"5.1","Tissue RNA - midbrain [nTPM]":"3.7","Tissue RNA - ovary [nTPM]":"7.1","Tissue RNA - pancreas [nTPM]":"7.9","Tissue RNA - parathyroid gland [nTPM]":"2.3","Tissue RNA - pituitary gland [nTPM]":"4.7","Tissue RNA - placenta [nTPM]":"5.9","Tissue RNA - pons [nTPM]":"4.1","Tissue RNA - prostate [nTPM]":"6.1","Tissue RNA - rectum [nTPM]":"2.2","Tissue RNA - retina [nTPM]":"1.9","Tissue RNA - salivary gland [nTPM]":"7.4","Tissue RNA - seminal vesicle [nTPM]":"2.6","Tissue RNA - skeletal muscle [nTPM]":"5.6","Tissue RNA - skin 1 [nTPM]":"9.2","Tissue RNA - small intestine [nTPM]":"10.1","Tissue RNA - smooth muscle [nTPM]":"2.3","Tissue RNA - spinal cord [nTPM]":"3.5","Tissue RNA - spleen [nTPM]":"12.8","Tissue RNA - stomach 1 [nTPM]":"6.2","Tissue RNA - testis [nTPM]":"13.3","Tissue RNA - thalamus [nTPM]":"4.1","Tissue RNA - thymus [nTPM]":"11.0","Tissue RNA - thyroid gland [nTPM]":"9.8","Tissue RNA - tongue [nTPM]":"1.5","Tissue RNA - tonsil [nTPM]":"5.2","Tissue RNA - urinary bladder [nTPM]":"5.9","Tissue RNA - vagina [nTPM]":"7.7","Tissue RNA - white matter [nTPM]":"4.4","Cell RNA - A-431 [nTPM]":"52.1","Cell RNA - A549 [nTPM]":"77.9","Cell RNA - AF22 [nTPM]":"27.9","Cell RNA - AN3-CA [nTPM]":"22.4","Cell RNA - ASC diff [nTPM]":"3.0","Cell RNA - ASC TERT1 [nTPM]":"2.8","Cell RNA - BEWO [nTPM]":"45.6","Cell RNA - BJ [nTPM]":"34.0","Cell RNA - BJ hTERT+ [nTPM]":"9.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"30.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"34.9","Cell RNA - CACO-2 [nTPM]":"42.4","Cell RNA - CAPAN-2 [nTPM]":"39.2","Cell RNA - Daudi [nTPM]":"84.6","Cell RNA - EFO-21 [nTPM]":"19.4","Cell RNA - fHDF\/TERT166 [nTPM]":"7.1","Cell RNA - GAMG [nTPM]":"13.9","Cell RNA - HaCaT [nTPM]":"45.1","Cell RNA - HAP1 [nTPM]":"27.4","Cell RNA - HBEC3-KT [nTPM]":"25.1","Cell RNA - HBF TERT88 [nTPM]":"6.8","Cell RNA - HDLM-2 [nTPM]":"64.4","Cell RNA - HEK 293 [nTPM]":"145.0","Cell RNA - HEL [nTPM]":"66.1","Cell RNA - HeLa [nTPM]":"73.0","Cell RNA - Hep G2 [nTPM]":"54.6","Cell RNA - HHSteC [nTPM]":"3.7","Cell RNA - HL-60 [nTPM]":"67.0","Cell RNA - HMC-1 [nTPM]":"57.7","Cell RNA - HSkMC [nTPM]":"6.4","Cell RNA - hTCEpi [nTPM]":"7.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.1","Cell RNA - hTERT-HME1 [nTPM]":"6.5","Cell RNA - hTERT-RPE1 [nTPM]":"6.0","Cell RNA - HUVEC TERT2 [nTPM]":"14.2","Cell RNA - JURKAT [nTPM]":"58.2","Cell RNA - K-562 [nTPM]":"77.4","Cell RNA - Karpas-707 [nTPM]":"54.3","Cell RNA - LHCN-M2 [nTPM]":"9.1","Cell RNA - MCF7 [nTPM]":"40.6","Cell RNA - MOLT-4 [nTPM]":"92.2","Cell RNA - NB-4 [nTPM]":"110.6","Cell RNA - NTERA-2 [nTPM]":"48.7","Cell RNA - OE19 [nTPM]":"25.3","Cell RNA - PC-3 [nTPM]":"55.4","Cell RNA - REH [nTPM]":"105.4","Cell RNA - RH-30 [nTPM]":"62.2","Cell RNA - RPMI-8226 [nTPM]":"67.7","Cell RNA - RPTEC TERT1 [nTPM]":"7.4","Cell RNA - RT4 [nTPM]":"44.9","Cell RNA - SCLC-21H [nTPM]":"39.3","Cell RNA - SH-SY5Y [nTPM]":"38.6","Cell RNA - SiHa [nTPM]":"33.0","Cell RNA - SK-BR-3 [nTPM]":"35.9","Cell RNA - SK-MEL-30 [nTPM]":"8.8","Cell RNA - SuSa [nTPM]":"10.1","Cell RNA - T-47d [nTPM]":"21.1","Cell RNA - THP-1 [nTPM]":"50.7","Cell RNA - TIME [nTPM]":"17.4","Cell RNA - U-138 MG [nTPM]":"21.4","Cell RNA - U-2 OS [nTPM]":"70.7","Cell RNA - U-2197 [nTPM]":"22.0","Cell RNA - U-251 MG [nTPM]":"56.5","Cell RNA - U-266\/70 [nTPM]":"60.0","Cell RNA - U-266\/84 [nTPM]":"91.3","Cell RNA - U-698 [nTPM]":"76.3","Cell RNA - U-87 MG [nTPM]":"21.2","Cell RNA - U-937 [nTPM]":"66.9","Cell RNA - WM-115 [nTPM]":"20.8","Blood RNA - basophil [nTPM]":"1.3","Blood RNA - classical monocyte [nTPM]":"4.3","Blood RNA - eosinophil [nTPM]":"1.5","Blood RNA - gdT-cell [nTPM]":"4.3","Blood RNA - intermediate monocyte [nTPM]":"5.6","Blood RNA - MAIT T-cell [nTPM]":"4.0","Blood RNA - memory B-cell [nTPM]":"6.0","Blood RNA - memory CD4 T-cell [nTPM]":"4.0","Blood RNA - memory CD8 T-cell [nTPM]":"3.5","Blood RNA - myeloid DC [nTPM]":"3.9","Blood RNA - naive B-cell [nTPM]":"5.4","Blood RNA - naive CD4 T-cell [nTPM]":"4.0","Blood RNA - naive CD8 T-cell [nTPM]":"3.9","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"4.2","Blood RNA - non-classical monocyte [nTPM]":"6.9","Blood RNA - plasmacytoid DC [nTPM]":"7.1","Blood RNA - T-reg [nTPM]":"3.1","Blood RNA - total PBMC [nTPM]":"4.0","Brain RNA - amygdala [nTPM]":"3.2","Brain RNA - basal ganglia [nTPM]":"3.7","Brain RNA - cerebellum [nTPM]":"4.5","Brain RNA - cerebral cortex [nTPM]":"3.8","Brain RNA - hippocampal formation [nTPM]":"2.7","Brain RNA - hypothalamus [nTPM]":"2.7","Brain RNA - medulla oblongata [nTPM]":"5.1","Brain RNA - midbrain [nTPM]":"3.7","Brain RNA - pons [nTPM]":"4.1","Brain RNA - spinal cord [nTPM]":"3.5","Brain RNA - thalamus [nTPM]":"4.1","Brain RNA - white matter [nTPM]":"4.4","Single Cell Type RNA - Adipocytes [nTPM]":"3.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"8.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"4.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"3.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.2","Single Cell Type RNA - dendritic cells [nTPM]":"3.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"4.8","Single Cell Type RNA - Early spermatids [nTPM]":"1.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.6","Single Cell Type RNA - Endothelial cells [nTPM]":"3.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"15.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.0","Single Cell Type RNA - Fibroblasts [nTPM]":"4.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"9.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"2.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"5.7","Single Cell Type RNA - Langerhans cells [nTPM]":"5.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.9","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"5.8","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"4.8","Single Cell Type RNA - Muller glia cells [nTPM]":"1.2","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.7","Single Cell Type RNA - Paneth cells [nTPM]":"51.3","Single Cell Type RNA - Peritubular cells [nTPM]":"5.3","Single Cell Type RNA - Plasma cells [nTPM]":"10.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.0","Single Cell Type RNA - Spermatocytes [nTPM]":"11.5","Single Cell Type RNA - Spermatogonia [nTPM]":"25.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.7","Single Cell Type RNA - T-cells [nTPM]":"5.4","Single Cell Type RNA - Theca cells [nTPM]":"3.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.3","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"POLG","Gene synonym":["POLG1","POLGA"],"Ensembl":"ENSG00000140521","Gene description":"DNA polymerase gamma, catalytic subunit","Uniprot":["P54098"],"Chromosome":"15","Position":"89305198-89334861","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA replication"],"Molecular function":["DNA-binding","DNA-directed DNA polymerase","Nucleotidyltransferase","Transferase"],"Disease involvement":["Disease variant","Epilepsy","Leigh syndrome","Neurodegeneration","Neuropathy","Primary mitochondrial disease","Progressive external ophthalmoplegia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056821","HPA078482"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 65: Plasmacytoid DCs - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA056821":"AB_2683247","HPA078482":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.73e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Tissue RNA - adipose tissue [nTPM]":"13.3","Tissue RNA - adrenal gland [nTPM]":"11.1","Tissue RNA - amygdala [nTPM]":"6.8","Tissue RNA - appendix [nTPM]":"4.0","Tissue RNA - basal ganglia [nTPM]":"5.0","Tissue RNA - bone marrow [nTPM]":"2.6","Tissue RNA - breast [nTPM]":"12.0","Tissue RNA - cerebellum [nTPM]":"4.8","Tissue RNA - cerebral cortex [nTPM]":"6.3","Tissue RNA - cervix [nTPM]":"12.0","Tissue RNA - choroid plexus [nTPM]":"4.5","Tissue RNA - colon [nTPM]":"13.3","Tissue RNA - duodenum [nTPM]":"5.5","Tissue RNA - endometrium 1 [nTPM]":"12.9","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"14.6","Tissue RNA - fallopian tube [nTPM]":"11.2","Tissue RNA - gallbladder [nTPM]":"0.9","Tissue RNA - heart muscle [nTPM]":"13.8","Tissue RNA - hippocampal formation [nTPM]":"6.1","Tissue RNA - hypothalamus [nTPM]":"3.5","Tissue RNA - kidney [nTPM]":"10.1","Tissue RNA - liver [nTPM]":"12.9","Tissue RNA - lung [nTPM]":"13.8","Tissue RNA - lymph node [nTPM]":"3.0","Tissue RNA - medulla oblongata [nTPM]":"9.0","Tissue RNA - midbrain [nTPM]":"5.8","Tissue RNA - ovary [nTPM]":"10.8","Tissue RNA - pancreas [nTPM]":"10.7","Tissue RNA - parathyroid gland [nTPM]":"2.9","Tissue RNA - pituitary gland [nTPM]":"8.4","Tissue RNA - placenta [nTPM]":"2.5","Tissue RNA - pons [nTPM]":"6.5","Tissue RNA - prostate [nTPM]":"10.5","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"1.4","Tissue RNA - salivary gland [nTPM]":"12.3","Tissue RNA - seminal vesicle [nTPM]":"2.2","Tissue RNA - skeletal muscle [nTPM]":"25.0","Tissue RNA - skin 1 [nTPM]":"16.0","Tissue RNA - small intestine [nTPM]":"14.5","Tissue RNA - smooth muscle [nTPM]":"1.3","Tissue RNA - spinal cord [nTPM]":"5.4","Tissue RNA - spleen [nTPM]":"16.2","Tissue RNA - stomach 1 [nTPM]":"11.9","Tissue RNA - testis [nTPM]":"5.4","Tissue RNA - thalamus [nTPM]":"5.7","Tissue RNA - thymus [nTPM]":"7.3","Tissue RNA - thyroid gland [nTPM]":"10.5","Tissue RNA - tongue [nTPM]":"10.9","Tissue RNA - tonsil [nTPM]":"2.4","Tissue RNA - urinary bladder [nTPM]":"12.2","Tissue RNA - vagina [nTPM]":"12.7","Tissue RNA - white matter [nTPM]":"6.3","Cell RNA - A-431 [nTPM]":"8.0","Cell RNA - A549 [nTPM]":"17.0","Cell RNA - AF22 [nTPM]":"6.7","Cell RNA - AN3-CA [nTPM]":"10.0","Cell RNA - ASC diff [nTPM]":"7.7","Cell RNA - ASC TERT1 [nTPM]":"1.6","Cell RNA - BEWO [nTPM]":"16.4","Cell RNA - BJ [nTPM]":"16.4","Cell RNA - BJ hTERT+ [nTPM]":"2.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.9","Cell RNA - CACO-2 [nTPM]":"28.0","Cell RNA - CAPAN-2 [nTPM]":"10.9","Cell RNA - Daudi [nTPM]":"14.4","Cell RNA - EFO-21 [nTPM]":"33.6","Cell RNA - fHDF\/TERT166 [nTPM]":"5.9","Cell RNA - GAMG [nTPM]":"16.9","Cell RNA - HaCaT [nTPM]":"11.8","Cell RNA - HAP1 [nTPM]":"14.3","Cell RNA - HBEC3-KT [nTPM]":"4.8","Cell RNA - HBF TERT88 [nTPM]":"0.9","Cell RNA - HDLM-2 [nTPM]":"35.8","Cell RNA - HEK 293 [nTPM]":"31.3","Cell RNA - HEL [nTPM]":"19.4","Cell RNA - HeLa [nTPM]":"19.5","Cell RNA - Hep G2 [nTPM]":"11.1","Cell RNA - HHSteC [nTPM]":"10.8","Cell RNA - HL-60 [nTPM]":"21.3","Cell RNA - HMC-1 [nTPM]":"33.6","Cell RNA - HSkMC [nTPM]":"2.4","Cell RNA - hTCEpi [nTPM]":"8.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.0","Cell RNA - hTERT-HME1 [nTPM]":"3.0","Cell RNA - hTERT-RPE1 [nTPM]":"8.3","Cell RNA - HUVEC TERT2 [nTPM]":"12.2","Cell RNA - JURKAT [nTPM]":"26.8","Cell RNA - K-562 [nTPM]":"19.5","Cell RNA - Karpas-707 [nTPM]":"5.4","Cell RNA - LHCN-M2 [nTPM]":"6.1","Cell RNA - MCF7 [nTPM]":"22.8","Cell RNA - MOLT-4 [nTPM]":"16.3","Cell RNA - NB-4 [nTPM]":"16.5","Cell RNA - NTERA-2 [nTPM]":"8.7","Cell RNA - OE19 [nTPM]":"13.7","Cell RNA - PC-3 [nTPM]":"8.2","Cell RNA - REH [nTPM]":"18.2","Cell RNA - RH-30 [nTPM]":"13.7","Cell RNA - RPMI-8226 [nTPM]":"17.4","Cell RNA - RPTEC TERT1 [nTPM]":"3.2","Cell RNA - RT4 [nTPM]":"19.2","Cell RNA - SCLC-21H [nTPM]":"24.5","Cell RNA - SH-SY5Y [nTPM]":"6.9","Cell RNA - SiHa [nTPM]":"26.8","Cell RNA - SK-BR-3 [nTPM]":"9.6","Cell RNA - SK-MEL-30 [nTPM]":"16.8","Cell RNA - SuSa [nTPM]":"6.0","Cell RNA - T-47d [nTPM]":"7.7","Cell RNA - THP-1 [nTPM]":"10.8","Cell RNA - TIME [nTPM]":"17.3","Cell RNA - U-138 MG [nTPM]":"12.8","Cell RNA - U-2 OS [nTPM]":"15.6","Cell RNA - U-2197 [nTPM]":"28.5","Cell RNA - U-251 MG [nTPM]":"14.2","Cell RNA - U-266\/70 [nTPM]":"17.0","Cell RNA - U-266\/84 [nTPM]":"9.4","Cell RNA - U-698 [nTPM]":"18.6","Cell RNA - U-87 MG [nTPM]":"9.5","Cell RNA - U-937 [nTPM]":"14.3","Cell RNA - WM-115 [nTPM]":"11.6","Blood RNA - basophil [nTPM]":"3.3","Blood RNA - classical monocyte [nTPM]":"4.3","Blood RNA - eosinophil [nTPM]":"6.1","Blood RNA - gdT-cell [nTPM]":"5.5","Blood RNA - intermediate monocyte [nTPM]":"4.0","Blood RNA - MAIT T-cell [nTPM]":"4.3","Blood RNA - memory B-cell [nTPM]":"2.0","Blood RNA - memory CD4 T-cell [nTPM]":"4.6","Blood RNA - memory CD8 T-cell [nTPM]":"6.8","Blood RNA - myeloid DC [nTPM]":"6.0","Blood RNA - naive B-cell [nTPM]":"3.0","Blood RNA - naive CD4 T-cell [nTPM]":"3.7","Blood RNA - naive CD8 T-cell [nTPM]":"4.4","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"5.0","Blood RNA - non-classical monocyte [nTPM]":"3.5","Blood RNA - plasmacytoid DC [nTPM]":"4.1","Blood RNA - T-reg [nTPM]":"3.3","Blood RNA - total PBMC [nTPM]":"5.3","Brain RNA - amygdala [nTPM]":"6.8","Brain RNA - basal ganglia [nTPM]":"5.0","Brain RNA - cerebellum [nTPM]":"4.8","Brain RNA - cerebral cortex [nTPM]":"6.3","Brain RNA - hippocampal formation [nTPM]":"6.1","Brain RNA - hypothalamus [nTPM]":"3.5","Brain RNA - medulla oblongata [nTPM]":"9.0","Brain RNA - midbrain [nTPM]":"5.8","Brain RNA - pons [nTPM]":"6.5","Brain RNA - spinal cord [nTPM]":"5.4","Brain RNA - thalamus [nTPM]":"5.7","Brain RNA - white matter [nTPM]":"6.3","Single Cell Type RNA - Adipocytes [nTPM]":"15.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.9","Single Cell Type RNA - Astrocytes [nTPM]":"11.4","Single Cell Type RNA - B-cells [nTPM]":"17.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"7.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"9.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.0","Single Cell Type RNA - dendritic cells [nTPM]":"33.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"10.4","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.4","Single Cell Type RNA - Endothelial cells [nTPM]":"12.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"9.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.8","Single Cell Type RNA - Fibroblasts [nTPM]":"11.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.3","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"14.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"17.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.7","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.9","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"18.5","Single Cell Type RNA - Langerhans cells [nTPM]":"14.7","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"14.3","Single Cell Type RNA - Macrophages [nTPM]":"17.2","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"21.8","Single Cell Type RNA - Muller glia cells [nTPM]":"6.1","Single Cell Type RNA - NK-cells [nTPM]":"30.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.4","Single Cell Type RNA - Paneth cells [nTPM]":"15.9","Single Cell Type RNA - Peritubular cells [nTPM]":"10.5","Single Cell Type RNA - Plasma cells [nTPM]":"16.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.9","Single Cell Type RNA - Spermatocytes [nTPM]":"9.2","Single Cell Type RNA - Spermatogonia [nTPM]":"11.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"21.8","Single Cell Type RNA - T-cells [nTPM]":"21.7","Single Cell Type RNA - Theca cells [nTPM]":"14.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.6","Single Cell Type RNA - Urothelial cells [nTPM]":"15.5"},{"Gene":"POLH","Gene synonym":["RAD30A","XP-V"],"Ensembl":"ENSG00000170734","Gene description":"DNA polymerase eta","Uniprot":["Q9Y253"],"Chromosome":"6","Position":"43576185-43620523","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","DNA replication","DNA synthesis"],"Molecular function":["DNA-binding","DNA-directed DNA polymerase","Mutator protein","Nucleotidyltransferase","Transferase"],"Disease involvement":["Disease variant","Xeroderma pigmentosum"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"25.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-698":"91.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006721","HPA026762"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA006721":"AB_1847785","HPA026762":"AB_10601248"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.0","Tissue RNA - adrenal gland [nTPM]":"3.8","Tissue RNA - amygdala [nTPM]":"2.3","Tissue RNA - appendix [nTPM]":"6.9","Tissue RNA - basal ganglia [nTPM]":"2.7","Tissue RNA - bone marrow [nTPM]":"4.2","Tissue RNA - breast [nTPM]":"4.8","Tissue RNA - cerebellum [nTPM]":"5.1","Tissue RNA - cerebral cortex [nTPM]":"2.9","Tissue RNA - cervix [nTPM]":"5.9","Tissue RNA - choroid plexus [nTPM]":"5.3","Tissue RNA - colon [nTPM]":"7.0","Tissue RNA - duodenum [nTPM]":"4.6","Tissue RNA - endometrium 1 [nTPM]":"4.2","Tissue RNA - epididymis [nTPM]":"3.6","Tissue RNA - esophagus [nTPM]":"5.5","Tissue RNA - fallopian tube [nTPM]":"5.5","Tissue RNA - gallbladder [nTPM]":"4.3","Tissue RNA - heart muscle [nTPM]":"3.7","Tissue RNA - hippocampal formation [nTPM]":"2.2","Tissue RNA - hypothalamus [nTPM]":"2.2","Tissue RNA - kidney [nTPM]":"4.7","Tissue RNA - liver [nTPM]":"5.6","Tissue RNA - lung [nTPM]":"5.7","Tissue RNA - lymph node [nTPM]":"12.9","Tissue RNA - medulla oblongata [nTPM]":"2.7","Tissue RNA - midbrain [nTPM]":"2.2","Tissue RNA - ovary [nTPM]":"4.7","Tissue RNA - pancreas [nTPM]":"5.4","Tissue RNA - parathyroid gland [nTPM]":"3.7","Tissue RNA - pituitary gland [nTPM]":"3.2","Tissue RNA - placenta [nTPM]":"4.0","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"4.7","Tissue RNA - rectum [nTPM]":"7.2","Tissue RNA - retina [nTPM]":"7.4","Tissue RNA - salivary gland [nTPM]":"4.0","Tissue RNA - seminal vesicle [nTPM]":"3.8","Tissue RNA - skeletal muscle [nTPM]":"8.5","Tissue RNA - skin 1 [nTPM]":"8.5","Tissue RNA - small intestine [nTPM]":"4.4","Tissue RNA - smooth muscle [nTPM]":"6.3","Tissue RNA - spinal cord [nTPM]":"1.8","Tissue RNA - spleen [nTPM]":"5.6","Tissue RNA - stomach 1 [nTPM]":"4.6","Tissue RNA - testis [nTPM]":"10.6","Tissue RNA - thalamus [nTPM]":"2.5","Tissue RNA - thymus [nTPM]":"12.9","Tissue RNA - thyroid gland [nTPM]":"6.8","Tissue RNA - tongue [nTPM]":"4.7","Tissue RNA - tonsil [nTPM]":"14.2","Tissue RNA - urinary bladder [nTPM]":"4.8","Tissue RNA - vagina [nTPM]":"4.3","Tissue RNA - white matter [nTPM]":"3.6","Cell RNA - A-431 [nTPM]":"46.7","Cell RNA - A549 [nTPM]":"9.7","Cell RNA - AF22 [nTPM]":"13.5","Cell RNA - AN3-CA [nTPM]":"19.9","Cell RNA - ASC diff [nTPM]":"17.6","Cell RNA - ASC TERT1 [nTPM]":"29.1","Cell RNA - BEWO [nTPM]":"33.0","Cell RNA - BJ [nTPM]":"48.6","Cell RNA - BJ hTERT+ [nTPM]":"13.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"26.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"29.2","Cell RNA - CACO-2 [nTPM]":"12.0","Cell RNA - CAPAN-2 [nTPM]":"7.9","Cell RNA - Daudi [nTPM]":"48.9","Cell RNA - EFO-21 [nTPM]":"12.0","Cell RNA - fHDF\/TERT166 [nTPM]":"17.6","Cell RNA - GAMG [nTPM]":"7.6","Cell RNA - HaCaT [nTPM]":"11.4","Cell RNA - HAP1 [nTPM]":"13.1","Cell RNA - HBEC3-KT [nTPM]":"28.6","Cell RNA - HBF TERT88 [nTPM]":"31.5","Cell RNA - HDLM-2 [nTPM]":"25.9","Cell RNA - HEK 293 [nTPM]":"10.0","Cell RNA - HEL [nTPM]":"15.3","Cell RNA - HeLa [nTPM]":"31.6","Cell RNA - Hep G2 [nTPM]":"35.5","Cell RNA - HHSteC [nTPM]":"13.4","Cell RNA - HL-60 [nTPM]":"26.8","Cell RNA - HMC-1 [nTPM]":"19.2","Cell RNA - HSkMC [nTPM]":"19.5","Cell RNA - hTCEpi [nTPM]":"33.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.5","Cell RNA - hTERT-HME1 [nTPM]":"11.3","Cell RNA - hTERT-RPE1 [nTPM]":"10.6","Cell RNA - HUVEC TERT2 [nTPM]":"24.3","Cell RNA - JURKAT [nTPM]":"14.5","Cell RNA - K-562 [nTPM]":"24.0","Cell RNA - Karpas-707 [nTPM]":"29.6","Cell RNA - LHCN-M2 [nTPM]":"33.0","Cell RNA - MCF7 [nTPM]":"15.0","Cell RNA - MOLT-4 [nTPM]":"23.9","Cell RNA - NB-4 [nTPM]":"6.4","Cell RNA - NTERA-2 [nTPM]":"4.2","Cell RNA - OE19 [nTPM]":"33.2","Cell RNA - PC-3 [nTPM]":"7.2","Cell RNA - REH [nTPM]":"25.1","Cell RNA - RH-30 [nTPM]":"14.3","Cell RNA - RPMI-8226 [nTPM]":"11.8","Cell RNA - RPTEC TERT1 [nTPM]":"9.9","Cell RNA - RT4 [nTPM]":"34.6","Cell RNA - SCLC-21H [nTPM]":"15.1","Cell RNA - SH-SY5Y [nTPM]":"5.4","Cell RNA - SiHa [nTPM]":"14.5","Cell RNA - SK-BR-3 [nTPM]":"12.9","Cell RNA - SK-MEL-30 [nTPM]":"7.3","Cell RNA - SuSa [nTPM]":"15.4","Cell RNA - T-47d [nTPM]":"17.9","Cell RNA - THP-1 [nTPM]":"10.8","Cell RNA - TIME [nTPM]":"36.2","Cell RNA - U-138 MG [nTPM]":"23.6","Cell RNA - U-2 OS [nTPM]":"24.4","Cell RNA - U-2197 [nTPM]":"12.2","Cell RNA - U-251 MG [nTPM]":"25.2","Cell RNA - U-266\/70 [nTPM]":"28.0","Cell RNA - U-266\/84 [nTPM]":"21.3","Cell RNA - U-698 [nTPM]":"91.1","Cell RNA - U-87 MG [nTPM]":"11.8","Cell RNA - U-937 [nTPM]":"14.5","Cell RNA - WM-115 [nTPM]":"27.3","Blood RNA - basophil [nTPM]":"4.1","Blood RNA - classical monocyte [nTPM]":"1.7","Blood RNA - eosinophil [nTPM]":"2.7","Blood RNA - gdT-cell [nTPM]":"4.2","Blood RNA - intermediate monocyte [nTPM]":"1.6","Blood RNA - MAIT T-cell [nTPM]":"3.8","Blood RNA - memory B-cell [nTPM]":"5.0","Blood RNA - memory CD4 T-cell [nTPM]":"3.5","Blood RNA - memory CD8 T-cell [nTPM]":"3.1","Blood RNA - myeloid DC [nTPM]":"1.3","Blood RNA - naive B-cell [nTPM]":"4.9","Blood RNA - naive CD4 T-cell [nTPM]":"2.8","Blood RNA - naive CD8 T-cell [nTPM]":"3.0","Blood RNA - neutrophil [nTPM]":"1.7","Blood RNA - NK-cell [nTPM]":"4.2","Blood RNA - non-classical monocyte [nTPM]":"1.6","Blood RNA - plasmacytoid DC [nTPM]":"2.6","Blood RNA - T-reg [nTPM]":"4.6","Blood RNA - total PBMC [nTPM]":"2.0","Brain RNA - amygdala [nTPM]":"2.3","Brain RNA - basal ganglia [nTPM]":"2.7","Brain RNA - cerebellum [nTPM]":"5.1","Brain RNA - cerebral cortex [nTPM]":"2.9","Brain RNA - hippocampal formation [nTPM]":"2.2","Brain RNA - hypothalamus [nTPM]":"2.2","Brain RNA - medulla oblongata [nTPM]":"2.7","Brain RNA - midbrain [nTPM]":"2.2","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"1.8","Brain RNA - thalamus [nTPM]":"2.5","Brain RNA - white matter [nTPM]":"3.6","Single Cell Type RNA - Adipocytes [nTPM]":"3.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.2","Single Cell Type RNA - Astrocytes [nTPM]":"12.1","Single Cell Type RNA - B-cells [nTPM]":"15.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.4","Single Cell Type RNA - Bipolar cells [nTPM]":"6.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"6.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.4","Single Cell Type RNA - dendritic cells [nTPM]":"5.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.1","Single Cell Type RNA - Early spermatids [nTPM]":"11.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.8","Single Cell Type RNA - Endothelial cells [nTPM]":"2.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"5.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.8","Single Cell Type RNA - Fibroblasts [nTPM]":"5.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"6.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"2.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.2","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"2.2","Single Cell Type RNA - Langerhans cells [nTPM]":"2.2","Single Cell Type RNA - Late spermatids [nTPM]":"7.3","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"3.0","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"3.2","Single Cell Type RNA - Muller glia cells [nTPM]":"2.6","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"13.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.9","Single Cell Type RNA - Paneth cells [nTPM]":"4.5","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"12.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.0","Single Cell Type RNA - Spermatocytes [nTPM]":"25.9","Single Cell Type RNA - Spermatogonia [nTPM]":"6.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - T-cells [nTPM]":"8.8","Single Cell Type RNA - Theca cells [nTPM]":"5.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.0","Single Cell Type RNA - Urothelial cells [nTPM]":"2.3"},{"Gene":"POLQ","Gene synonym":["POLH"],"Ensembl":"ENSG00000051341","Gene description":"DNA polymerase theta","Uniprot":["O75417"],"Chromosome":"3","Position":"121431427-121546641","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["DNA-directed DNA polymerase","Nucleotidyltransferase","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"6.0","lymphoid tissue":"4.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"16.4","Excitatory neurons":"9.5","Granulosa cells":"12.6","Inhibitory neurons":"7.8","Plasma cells":"12.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"1.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"2.5"},"Antibody":["HPA053359"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus","Cytosol"],"Antibody RRID":{"HPA053359":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.46e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.04e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"1.6","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"6.0","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"1.0","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.2","Tissue RNA - duodenum [nTPM]":"1.2","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"2.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"2.8","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"1.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"2.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"1.4","Tissue RNA - small intestine [nTPM]":"0.9","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.8","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"2.2","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"4.5","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"2.3","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"18.2","Cell RNA - A549 [nTPM]":"12.1","Cell RNA - AF22 [nTPM]":"10.2","Cell RNA - AN3-CA [nTPM]":"7.2","Cell RNA - ASC diff [nTPM]":"0.9","Cell RNA - ASC TERT1 [nTPM]":"1.2","Cell RNA - BEWO [nTPM]":"9.2","Cell RNA - BJ [nTPM]":"8.5","Cell RNA - BJ hTERT+ [nTPM]":"3.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.9","Cell RNA - CACO-2 [nTPM]":"9.8","Cell RNA - CAPAN-2 [nTPM]":"6.6","Cell RNA - Daudi [nTPM]":"21.5","Cell RNA - EFO-21 [nTPM]":"3.7","Cell RNA - fHDF\/TERT166 [nTPM]":"4.6","Cell RNA - GAMG [nTPM]":"11.7","Cell RNA - HaCaT [nTPM]":"14.0","Cell RNA - HAP1 [nTPM]":"12.2","Cell RNA - HBEC3-KT [nTPM]":"5.4","Cell RNA - HBF TERT88 [nTPM]":"16.4","Cell RNA - HDLM-2 [nTPM]":"6.3","Cell RNA - HEK 293 [nTPM]":"6.7","Cell RNA - HEL [nTPM]":"13.8","Cell RNA - HeLa [nTPM]":"8.0","Cell RNA - Hep G2 [nTPM]":"6.1","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"15.1","Cell RNA - HMC-1 [nTPM]":"12.1","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.9","Cell RNA - hTERT-HME1 [nTPM]":"5.4","Cell RNA - hTERT-RPE1 [nTPM]":"1.7","Cell RNA - HUVEC TERT2 [nTPM]":"4.9","Cell RNA - JURKAT [nTPM]":"7.9","Cell RNA - K-562 [nTPM]":"9.3","Cell RNA - Karpas-707 [nTPM]":"15.9","Cell RNA - LHCN-M2 [nTPM]":"10.3","Cell RNA - MCF7 [nTPM]":"7.1","Cell RNA - MOLT-4 [nTPM]":"13.7","Cell RNA - NB-4 [nTPM]":"8.8","Cell RNA - NTERA-2 [nTPM]":"9.7","Cell RNA - OE19 [nTPM]":"5.5","Cell RNA - PC-3 [nTPM]":"5.9","Cell RNA - REH [nTPM]":"11.4","Cell RNA - RH-30 [nTPM]":"12.2","Cell RNA - RPMI-8226 [nTPM]":"7.6","Cell RNA - RPTEC TERT1 [nTPM]":"3.1","Cell RNA - RT4 [nTPM]":"10.3","Cell RNA - SCLC-21H [nTPM]":"5.5","Cell RNA - SH-SY5Y [nTPM]":"5.0","Cell RNA - SiHa [nTPM]":"9.8","Cell RNA - SK-BR-3 [nTPM]":"5.2","Cell RNA - SK-MEL-30 [nTPM]":"3.4","Cell RNA - SuSa [nTPM]":"8.8","Cell RNA - T-47d [nTPM]":"4.8","Cell RNA - THP-1 [nTPM]":"14.8","Cell RNA - TIME [nTPM]":"3.8","Cell RNA - U-138 MG [nTPM]":"8.6","Cell RNA - U-2 OS [nTPM]":"11.2","Cell RNA - U-2197 [nTPM]":"3.4","Cell RNA - U-251 MG [nTPM]":"11.1","Cell RNA - U-266\/70 [nTPM]":"8.0","Cell RNA - U-266\/84 [nTPM]":"6.9","Cell RNA - U-698 [nTPM]":"21.8","Cell RNA - U-87 MG [nTPM]":"4.1","Cell RNA - U-937 [nTPM]":"11.0","Cell RNA - WM-115 [nTPM]":"6.4","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"1.0","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"16.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.3","Single Cell Type RNA - Fibroblasts [nTPM]":"1.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"12.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.6","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"1.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"12.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.0","Single Cell Type RNA - Spermatocytes [nTPM]":"6.8","Single Cell Type RNA - Spermatogonia [nTPM]":"3.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"1.8","Single Cell Type RNA - Theca cells [nTPM]":"0.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"POLR1A","Gene synonym":["DKFZP586M0122","FLJ21915","RPA1","RPA190","RPO1-4"],"Ensembl":"ENSG00000068654","Gene description":"RNA polymerase I subunit A","Uniprot":["O95602"],"Chromosome":"2","Position":"86020216-86106155","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","RNA polymerase related proteins"],"Biological process":["Transcription"],"Molecular function":["Nucleotidyltransferase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010145","HPA031513","HPA049700"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Intermediate filaments"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":["Nucleoplasm","Intermediate filaments"],"Antibody RRID":{"CAB010145":"AB_675814","HPA031513":"AB_2673916","HPA049700":"AB_2680856"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.70e-9"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.37e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.41e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.4","Tissue RNA - adrenal gland [nTPM]":"5.7","Tissue RNA - amygdala [nTPM]":"3.7","Tissue RNA - appendix [nTPM]":"5.8","Tissue RNA - basal ganglia [nTPM]":"4.0","Tissue RNA - bone marrow [nTPM]":"4.9","Tissue RNA - breast [nTPM]":"4.5","Tissue RNA - cerebellum [nTPM]":"3.1","Tissue RNA - cerebral cortex [nTPM]":"4.7","Tissue RNA - cervix [nTPM]":"4.9","Tissue RNA - choroid plexus [nTPM]":"4.0","Tissue RNA - colon [nTPM]":"4.9","Tissue RNA - duodenum [nTPM]":"4.1","Tissue RNA - endometrium 1 [nTPM]":"8.2","Tissue RNA - epididymis [nTPM]":"3.0","Tissue RNA - esophagus [nTPM]":"6.0","Tissue RNA - fallopian tube [nTPM]":"5.2","Tissue RNA - gallbladder [nTPM]":"2.9","Tissue RNA - heart muscle [nTPM]":"5.8","Tissue RNA - hippocampal formation [nTPM]":"3.9","Tissue RNA - hypothalamus [nTPM]":"3.6","Tissue RNA - kidney [nTPM]":"4.6","Tissue RNA - liver [nTPM]":"5.0","Tissue RNA - lung [nTPM]":"4.0","Tissue RNA - lymph node [nTPM]":"4.6","Tissue RNA - medulla oblongata [nTPM]":"3.4","Tissue RNA - midbrain [nTPM]":"3.6","Tissue RNA - ovary [nTPM]":"5.2","Tissue RNA - pancreas [nTPM]":"5.2","Tissue RNA - parathyroid gland [nTPM]":"7.1","Tissue RNA - pituitary gland [nTPM]":"4.9","Tissue RNA - placenta [nTPM]":"5.0","Tissue RNA - pons [nTPM]":"3.3","Tissue RNA - prostate [nTPM]":"4.5","Tissue RNA - rectum [nTPM]":"5.0","Tissue RNA - retina [nTPM]":"3.5","Tissue RNA - salivary gland [nTPM]":"3.9","Tissue RNA - seminal vesicle [nTPM]":"5.1","Tissue RNA - skeletal muscle [nTPM]":"10.8","Tissue RNA - skin 1 [nTPM]":"5.5","Tissue RNA - small intestine [nTPM]":"3.8","Tissue RNA - smooth muscle [nTPM]":"6.9","Tissue RNA - spinal cord [nTPM]":"2.7","Tissue RNA - spleen [nTPM]":"3.8","Tissue RNA - stomach 1 [nTPM]":"4.5","Tissue RNA - testis [nTPM]":"6.2","Tissue RNA - thalamus [nTPM]":"4.4","Tissue RNA - thymus [nTPM]":"6.2","Tissue RNA - thyroid gland [nTPM]":"4.5","Tissue RNA - tongue [nTPM]":"7.4","Tissue RNA - tonsil [nTPM]":"4.9","Tissue RNA - urinary bladder [nTPM]":"5.2","Tissue RNA - vagina [nTPM]":"4.2","Tissue RNA - white matter [nTPM]":"4.3","Cell RNA - A-431 [nTPM]":"18.5","Cell RNA - A549 [nTPM]":"41.1","Cell RNA - AF22 [nTPM]":"18.0","Cell RNA - AN3-CA [nTPM]":"34.7","Cell RNA - ASC diff [nTPM]":"17.2","Cell RNA - ASC TERT1 [nTPM]":"13.7","Cell RNA - BEWO [nTPM]":"25.9","Cell RNA - BJ [nTPM]":"16.6","Cell RNA - BJ hTERT+ [nTPM]":"10.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.4","Cell RNA - CACO-2 [nTPM]":"51.9","Cell RNA - CAPAN-2 [nTPM]":"14.2","Cell RNA - Daudi [nTPM]":"41.9","Cell RNA - EFO-21 [nTPM]":"17.2","Cell RNA - fHDF\/TERT166 [nTPM]":"17.0","Cell RNA - GAMG [nTPM]":"22.7","Cell RNA - HaCaT [nTPM]":"20.9","Cell RNA - HAP1 [nTPM]":"46.6","Cell RNA - HBEC3-KT [nTPM]":"24.4","Cell RNA - HBF TERT88 [nTPM]":"20.6","Cell RNA - HDLM-2 [nTPM]":"17.6","Cell RNA - HEK 293 [nTPM]":"24.0","Cell RNA - HEL [nTPM]":"36.2","Cell RNA - HeLa [nTPM]":"18.0","Cell RNA - Hep G2 [nTPM]":"35.1","Cell RNA - HHSteC [nTPM]":"12.1","Cell RNA - HL-60 [nTPM]":"34.8","Cell RNA - HMC-1 [nTPM]":"18.7","Cell RNA - HSkMC [nTPM]":"10.5","Cell RNA - hTCEpi [nTPM]":"15.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"34.6","Cell RNA - hTERT-HME1 [nTPM]":"26.7","Cell RNA - hTERT-RPE1 [nTPM]":"8.8","Cell RNA - HUVEC TERT2 [nTPM]":"18.2","Cell RNA - JURKAT [nTPM]":"19.0","Cell RNA - K-562 [nTPM]":"48.8","Cell RNA - Karpas-707 [nTPM]":"10.3","Cell RNA - LHCN-M2 [nTPM]":"16.2","Cell RNA - MCF7 [nTPM]":"16.4","Cell RNA - MOLT-4 [nTPM]":"25.8","Cell RNA - NB-4 [nTPM]":"15.1","Cell RNA - NTERA-2 [nTPM]":"32.7","Cell RNA - OE19 [nTPM]":"24.4","Cell RNA - PC-3 [nTPM]":"26.8","Cell RNA - REH [nTPM]":"30.7","Cell RNA - RH-30 [nTPM]":"39.5","Cell RNA - RPMI-8226 [nTPM]":"19.6","Cell RNA - RPTEC TERT1 [nTPM]":"10.5","Cell RNA - RT4 [nTPM]":"29.7","Cell RNA - SCLC-21H [nTPM]":"27.7","Cell RNA - SH-SY5Y [nTPM]":"14.6","Cell RNA - SiHa [nTPM]":"18.3","Cell RNA - SK-BR-3 [nTPM]":"23.8","Cell RNA - SK-MEL-30 [nTPM]":"12.7","Cell RNA - SuSa [nTPM]":"12.3","Cell RNA - T-47d [nTPM]":"14.0","Cell RNA - THP-1 [nTPM]":"12.0","Cell RNA - TIME [nTPM]":"29.3","Cell RNA - U-138 MG [nTPM]":"28.0","Cell RNA - U-2 OS [nTPM]":"22.2","Cell RNA - U-2197 [nTPM]":"24.3","Cell RNA - U-251 MG [nTPM]":"33.8","Cell RNA - U-266\/70 [nTPM]":"14.5","Cell RNA - U-266\/84 [nTPM]":"15.3","Cell RNA - U-698 [nTPM]":"35.7","Cell RNA - U-87 MG [nTPM]":"14.6","Cell RNA - U-937 [nTPM]":"29.3","Cell RNA - WM-115 [nTPM]":"25.3","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"0.9","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"3.7","Brain RNA - basal ganglia [nTPM]":"4.0","Brain RNA - cerebellum [nTPM]":"3.1","Brain RNA - cerebral cortex [nTPM]":"4.7","Brain RNA - hippocampal formation [nTPM]":"3.9","Brain RNA - hypothalamus [nTPM]":"3.6","Brain RNA - medulla oblongata [nTPM]":"3.4","Brain RNA - midbrain [nTPM]":"3.6","Brain RNA - pons [nTPM]":"3.3","Brain RNA - spinal cord [nTPM]":"2.7","Brain RNA - thalamus [nTPM]":"4.4","Brain RNA - white matter [nTPM]":"4.3","Single Cell Type RNA - Adipocytes [nTPM]":"4.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.1","Single Cell Type RNA - Astrocytes [nTPM]":"13.4","Single Cell Type RNA - B-cells [nTPM]":"8.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.0","Single Cell Type RNA - Bipolar cells [nTPM]":"12.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"4.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.3","Single Cell Type RNA - dendritic cells [nTPM]":"7.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.8","Single Cell Type RNA - Endothelial cells [nTPM]":"6.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"10.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.4","Single Cell Type RNA - Fibroblasts [nTPM]":"7.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.9","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"11.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.2","Single Cell Type RNA - Hepatocytes [nTPM]":"8.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.5","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.7","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.1","Single Cell Type RNA - Langerhans cells [nTPM]":"3.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.7","Single Cell Type RNA - Leydig cells [nTPM]":"6.2","Single Cell Type RNA - Macrophages [nTPM]":"5.5","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"3.3","Single Cell Type RNA - Muller glia cells [nTPM]":"4.2","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.6","Single Cell Type RNA - Paneth cells [nTPM]":"3.0","Single Cell Type RNA - Peritubular cells [nTPM]":"5.3","Single Cell Type RNA - Plasma cells [nTPM]":"10.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.2","Single Cell Type RNA - Spermatocytes [nTPM]":"5.0","Single Cell Type RNA - Spermatogonia [nTPM]":"7.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.8","Single Cell Type RNA - T-cells [nTPM]":"7.5","Single Cell Type RNA - Theca cells [nTPM]":"12.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.4","Single Cell Type RNA - Urothelial cells [nTPM]":"4.0"},{"Gene":"POLR3A","Gene synonym":["C160","hRPC155","RPC1","RPC155"],"Ensembl":"ENSG00000148606","Gene description":"RNA polymerase III subunit A","Uniprot":["O14802"],"Chromosome":"10","Position":"77969251-78029515","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","RNA polymerase related proteins"],"Biological process":["Antiviral defense","Immunity","Innate immunity","Transcription"],"Molecular function":["Nucleotidyltransferase","Transferase"],"Disease involvement":["Disease variant","Leukodystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"64.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"PC-3":"75.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037926"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA037926":"AB_10672400"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.64e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.3","Tissue RNA - adrenal gland [nTPM]":"6.0","Tissue RNA - amygdala [nTPM]":"6.6","Tissue RNA - appendix [nTPM]":"5.2","Tissue RNA - basal ganglia [nTPM]":"7.1","Tissue RNA - bone marrow [nTPM]":"3.9","Tissue RNA - breast [nTPM]":"6.2","Tissue RNA - cerebellum [nTPM]":"6.7","Tissue RNA - cerebral cortex [nTPM]":"7.9","Tissue RNA - cervix [nTPM]":"5.1","Tissue RNA - choroid plexus [nTPM]":"4.7","Tissue RNA - colon [nTPM]":"4.8","Tissue RNA - duodenum [nTPM]":"5.1","Tissue RNA - endometrium 1 [nTPM]":"5.5","Tissue RNA - epididymis [nTPM]":"7.5","Tissue RNA - esophagus [nTPM]":"5.0","Tissue RNA - fallopian tube [nTPM]":"4.8","Tissue RNA - gallbladder [nTPM]":"3.7","Tissue RNA - heart muscle [nTPM]":"4.9","Tissue RNA - hippocampal formation [nTPM]":"8.1","Tissue RNA - hypothalamus [nTPM]":"3.7","Tissue RNA - kidney [nTPM]":"5.2","Tissue RNA - liver [nTPM]":"5.6","Tissue RNA - lung [nTPM]":"4.0","Tissue RNA - lymph node [nTPM]":"5.7","Tissue RNA - medulla oblongata [nTPM]":"5.5","Tissue RNA - midbrain [nTPM]":"3.4","Tissue RNA - ovary [nTPM]":"6.5","Tissue RNA - pancreas [nTPM]":"5.4","Tissue RNA - parathyroid gland [nTPM]":"6.8","Tissue RNA - pituitary gland [nTPM]":"10.4","Tissue RNA - placenta [nTPM]":"6.1","Tissue RNA - pons [nTPM]":"5.5","Tissue RNA - prostate [nTPM]":"5.8","Tissue RNA - rectum [nTPM]":"5.7","Tissue RNA - retina [nTPM]":"12.8","Tissue RNA - salivary gland [nTPM]":"5.0","Tissue RNA - seminal vesicle [nTPM]":"4.5","Tissue RNA - skeletal muscle [nTPM]":"11.5","Tissue RNA - skin 1 [nTPM]":"6.7","Tissue RNA - small intestine [nTPM]":"4.7","Tissue RNA - smooth muscle [nTPM]":"5.6","Tissue RNA - spinal cord [nTPM]":"2.2","Tissue RNA - spleen [nTPM]":"5.1","Tissue RNA - stomach 1 [nTPM]":"4.7","Tissue RNA - testis [nTPM]":"6.0","Tissue RNA - thalamus [nTPM]":"4.0","Tissue RNA - thymus [nTPM]":"7.6","Tissue RNA - thyroid gland [nTPM]":"5.6","Tissue RNA - tongue [nTPM]":"8.7","Tissue RNA - tonsil [nTPM]":"6.3","Tissue RNA - urinary bladder [nTPM]":"5.0","Tissue RNA - vagina [nTPM]":"4.8","Tissue RNA - white matter [nTPM]":"6.5","Cell RNA - A-431 [nTPM]":"14.2","Cell RNA - A549 [nTPM]":"16.3","Cell RNA - AF22 [nTPM]":"17.4","Cell RNA - AN3-CA [nTPM]":"28.8","Cell RNA - ASC diff [nTPM]":"11.2","Cell RNA - ASC TERT1 [nTPM]":"14.2","Cell RNA - BEWO [nTPM]":"11.6","Cell RNA - BJ [nTPM]":"16.0","Cell RNA - BJ hTERT+ [nTPM]":"20.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.8","Cell RNA - CACO-2 [nTPM]":"22.1","Cell RNA - CAPAN-2 [nTPM]":"10.0","Cell RNA - Daudi [nTPM]":"17.6","Cell RNA - EFO-21 [nTPM]":"9.7","Cell RNA - fHDF\/TERT166 [nTPM]":"14.0","Cell RNA - GAMG [nTPM]":"11.5","Cell RNA - HaCaT [nTPM]":"15.7","Cell RNA - HAP1 [nTPM]":"30.3","Cell RNA - HBEC3-KT [nTPM]":"17.5","Cell RNA - HBF TERT88 [nTPM]":"24.4","Cell RNA - HDLM-2 [nTPM]":"13.0","Cell RNA - HEK 293 [nTPM]":"22.2","Cell RNA - HEL [nTPM]":"14.2","Cell RNA - HeLa [nTPM]":"13.6","Cell RNA - Hep G2 [nTPM]":"26.6","Cell RNA - HHSteC [nTPM]":"10.5","Cell RNA - HL-60 [nTPM]":"24.6","Cell RNA - HMC-1 [nTPM]":"11.5","Cell RNA - HSkMC [nTPM]":"12.2","Cell RNA - hTCEpi [nTPM]":"12.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"35.9","Cell RNA - hTERT-HME1 [nTPM]":"33.0","Cell RNA - hTERT-RPE1 [nTPM]":"19.4","Cell RNA - HUVEC TERT2 [nTPM]":"18.0","Cell RNA - JURKAT [nTPM]":"14.1","Cell RNA - K-562 [nTPM]":"26.8","Cell RNA - Karpas-707 [nTPM]":"10.6","Cell RNA - LHCN-M2 [nTPM]":"19.9","Cell RNA - MCF7 [nTPM]":"10.6","Cell RNA - MOLT-4 [nTPM]":"18.7","Cell RNA - NB-4 [nTPM]":"15.6","Cell RNA - NTERA-2 [nTPM]":"19.0","Cell RNA - OE19 [nTPM]":"11.0","Cell RNA - PC-3 [nTPM]":"75.1","Cell RNA - REH [nTPM]":"17.5","Cell RNA - RH-30 [nTPM]":"11.0","Cell RNA - RPMI-8226 [nTPM]":"11.5","Cell RNA - RPTEC TERT1 [nTPM]":"10.0","Cell RNA - RT4 [nTPM]":"8.6","Cell RNA - SCLC-21H [nTPM]":"15.5","Cell RNA - SH-SY5Y [nTPM]":"20.0","Cell RNA - SiHa [nTPM]":"15.4","Cell RNA - SK-BR-3 [nTPM]":"28.3","Cell RNA - SK-MEL-30 [nTPM]":"16.6","Cell RNA - SuSa [nTPM]":"15.5","Cell RNA - T-47d [nTPM]":"21.0","Cell RNA - THP-1 [nTPM]":"12.7","Cell RNA - TIME [nTPM]":"19.8","Cell RNA - U-138 MG [nTPM]":"12.9","Cell RNA - U-2 OS [nTPM]":"12.5","Cell RNA - U-2197 [nTPM]":"14.2","Cell RNA - U-251 MG [nTPM]":"32.0","Cell RNA - U-266\/70 [nTPM]":"16.4","Cell RNA - U-266\/84 [nTPM]":"18.6","Cell RNA - U-698 [nTPM]":"21.0","Cell RNA - U-87 MG [nTPM]":"23.0","Cell RNA - U-937 [nTPM]":"25.4","Cell RNA - WM-115 [nTPM]":"6.4","Blood RNA - basophil [nTPM]":"5.4","Blood RNA - classical monocyte [nTPM]":"2.6","Blood RNA - eosinophil [nTPM]":"1.5","Blood RNA - gdT-cell [nTPM]":"3.5","Blood RNA - intermediate monocyte [nTPM]":"3.1","Blood RNA - MAIT T-cell [nTPM]":"3.5","Blood RNA - memory B-cell [nTPM]":"2.6","Blood RNA - memory CD4 T-cell [nTPM]":"2.8","Blood RNA - memory CD8 T-cell [nTPM]":"3.4","Blood RNA - myeloid DC [nTPM]":"2.4","Blood RNA - naive B-cell [nTPM]":"3.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.5","Blood RNA - naive CD8 T-cell [nTPM]":"3.0","Blood RNA - neutrophil [nTPM]":"1.5","Blood RNA - NK-cell [nTPM]":"3.4","Blood RNA - non-classical monocyte [nTPM]":"2.9","Blood RNA - plasmacytoid DC [nTPM]":"2.6","Blood RNA - T-reg [nTPM]":"4.6","Blood RNA - total PBMC [nTPM]":"1.9","Brain RNA - amygdala [nTPM]":"6.6","Brain RNA - basal ganglia [nTPM]":"7.1","Brain RNA - cerebellum [nTPM]":"6.7","Brain RNA - cerebral cortex [nTPM]":"7.9","Brain RNA - hippocampal formation [nTPM]":"8.1","Brain RNA - hypothalamus [nTPM]":"3.7","Brain RNA - medulla oblongata [nTPM]":"5.5","Brain RNA - midbrain [nTPM]":"3.4","Brain RNA - pons [nTPM]":"5.5","Brain RNA - spinal cord [nTPM]":"2.2","Brain RNA - thalamus [nTPM]":"4.0","Brain RNA - white matter [nTPM]":"6.5","Single Cell Type RNA - Adipocytes [nTPM]":"8.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.1","Single Cell Type RNA - Astrocytes [nTPM]":"17.0","Single Cell Type RNA - B-cells [nTPM]":"8.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"28.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"9.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"64.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.0","Single Cell Type RNA - dendritic cells [nTPM]":"12.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.4","Single Cell Type RNA - Endothelial cells [nTPM]":"8.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"11.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"26.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.9","Single Cell Type RNA - Fibroblasts [nTPM]":"8.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.9","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"15.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"9.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.5","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"26.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"6.9","Single Cell Type RNA - Langerhans cells [nTPM]":"3.7","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"13.1","Single Cell Type RNA - Macrophages [nTPM]":"5.9","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"7.8","Single Cell Type RNA - Muller glia cells [nTPM]":"13.0","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.1","Single Cell Type RNA - Paneth cells [nTPM]":"8.3","Single Cell Type RNA - Peritubular cells [nTPM]":"8.2","Single Cell Type RNA - Plasma cells [nTPM]":"11.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"31.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.3","Single Cell Type RNA - Spermatocytes [nTPM]":"12.5","Single Cell Type RNA - Spermatogonia [nTPM]":"18.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.1","Single Cell Type RNA - T-cells [nTPM]":"7.8","Single Cell Type RNA - Theca cells [nTPM]":"13.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.6","Single Cell Type RNA - Urothelial cells [nTPM]":"3.6"},{"Gene":"POLR3B","Gene synonym":["C128","FLJ10388","RPC2"],"Ensembl":"ENSG00000013503","Gene description":"RNA polymerase III subunit B","Uniprot":["Q9NW08"],"Chromosome":"12","Position":"106357748-106510198","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","RNA polymerase related proteins"],"Biological process":["Antiviral defense","Immunity","Innate immunity","Transcription"],"Molecular function":["Nucleotidyltransferase","Transferase"],"Disease involvement":["Disease variant","Leukodystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"24.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036466"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA036466":"AB_10671842"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.21e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.5","Tissue RNA - adrenal gland [nTPM]":"8.7","Tissue RNA - amygdala [nTPM]":"3.1","Tissue RNA - appendix [nTPM]":"4.8","Tissue RNA - basal ganglia [nTPM]":"4.4","Tissue RNA - bone marrow [nTPM]":"5.2","Tissue RNA - breast [nTPM]":"5.0","Tissue RNA - cerebellum [nTPM]":"4.3","Tissue RNA - cerebral cortex [nTPM]":"4.6","Tissue RNA - cervix [nTPM]":"4.7","Tissue RNA - choroid plexus [nTPM]":"3.7","Tissue RNA - colon [nTPM]":"5.3","Tissue RNA - duodenum [nTPM]":"4.2","Tissue RNA - endometrium 1 [nTPM]":"4.6","Tissue RNA - epididymis [nTPM]":"5.2","Tissue RNA - esophagus [nTPM]":"8.6","Tissue RNA - fallopian tube [nTPM]":"5.1","Tissue RNA - gallbladder [nTPM]":"3.6","Tissue RNA - heart muscle [nTPM]":"5.8","Tissue RNA - hippocampal formation [nTPM]":"3.4","Tissue RNA - hypothalamus [nTPM]":"2.9","Tissue RNA - kidney [nTPM]":"6.8","Tissue RNA - liver [nTPM]":"9.0","Tissue RNA - lung [nTPM]":"4.7","Tissue RNA - lymph node [nTPM]":"4.1","Tissue RNA - medulla oblongata [nTPM]":"2.2","Tissue RNA - midbrain [nTPM]":"2.3","Tissue RNA - ovary [nTPM]":"7.5","Tissue RNA - pancreas [nTPM]":"4.9","Tissue RNA - parathyroid gland [nTPM]":"11.1","Tissue RNA - pituitary gland [nTPM]":"2.4","Tissue RNA - placenta [nTPM]":"6.7","Tissue RNA - pons [nTPM]":"2.3","Tissue RNA - prostate [nTPM]":"5.6","Tissue RNA - rectum [nTPM]":"5.7","Tissue RNA - retina [nTPM]":"6.2","Tissue RNA - salivary gland [nTPM]":"4.7","Tissue RNA - seminal vesicle [nTPM]":"4.0","Tissue RNA - skeletal muscle [nTPM]":"6.5","Tissue RNA - skin 1 [nTPM]":"11.0","Tissue RNA - small intestine [nTPM]":"3.4","Tissue RNA - smooth muscle [nTPM]":"5.4","Tissue RNA - spinal cord [nTPM]":"2.7","Tissue RNA - spleen [nTPM]":"3.3","Tissue RNA - stomach 1 [nTPM]":"5.4","Tissue RNA - testis [nTPM]":"6.1","Tissue RNA - thalamus [nTPM]":"3.2","Tissue RNA - thymus [nTPM]":"4.7","Tissue RNA - thyroid gland [nTPM]":"6.0","Tissue RNA - tongue [nTPM]":"8.3","Tissue RNA - tonsil [nTPM]":"5.6","Tissue RNA - urinary bladder [nTPM]":"4.9","Tissue RNA - vagina [nTPM]":"4.3","Tissue RNA - white matter [nTPM]":"3.6","Cell RNA - A-431 [nTPM]":"16.2","Cell RNA - A549 [nTPM]":"7.6","Cell RNA - AF22 [nTPM]":"16.4","Cell RNA - AN3-CA [nTPM]":"7.8","Cell RNA - ASC diff [nTPM]":"13.9","Cell RNA - ASC TERT1 [nTPM]":"13.1","Cell RNA - BEWO [nTPM]":"22.9","Cell RNA - BJ [nTPM]":"21.9","Cell RNA - BJ hTERT+ [nTPM]":"13.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.6","Cell RNA - CACO-2 [nTPM]":"14.0","Cell RNA - CAPAN-2 [nTPM]":"4.4","Cell RNA - Daudi [nTPM]":"20.6","Cell RNA - EFO-21 [nTPM]":"7.7","Cell RNA - fHDF\/TERT166 [nTPM]":"14.2","Cell RNA - GAMG [nTPM]":"5.6","Cell RNA - HaCaT [nTPM]":"14.8","Cell RNA - HAP1 [nTPM]":"19.5","Cell RNA - HBEC3-KT [nTPM]":"19.2","Cell RNA - HBF TERT88 [nTPM]":"18.5","Cell RNA - HDLM-2 [nTPM]":"16.6","Cell RNA - HEK 293 [nTPM]":"13.1","Cell RNA - HEL [nTPM]":"15.7","Cell RNA - HeLa [nTPM]":"10.1","Cell RNA - Hep G2 [nTPM]":"12.0","Cell RNA - HHSteC [nTPM]":"9.2","Cell RNA - HL-60 [nTPM]":"26.1","Cell RNA - HMC-1 [nTPM]":"17.0","Cell RNA - HSkMC [nTPM]":"11.7","Cell RNA - hTCEpi [nTPM]":"13.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.1","Cell RNA - hTERT-HME1 [nTPM]":"17.3","Cell RNA - hTERT-RPE1 [nTPM]":"10.3","Cell RNA - HUVEC TERT2 [nTPM]":"11.5","Cell RNA - JURKAT [nTPM]":"9.8","Cell RNA - K-562 [nTPM]":"24.5","Cell RNA - Karpas-707 [nTPM]":"6.5","Cell RNA - LHCN-M2 [nTPM]":"11.2","Cell RNA - MCF7 [nTPM]":"12.0","Cell RNA - MOLT-4 [nTPM]":"19.1","Cell RNA - NB-4 [nTPM]":"8.7","Cell RNA - NTERA-2 [nTPM]":"17.8","Cell RNA - OE19 [nTPM]":"11.9","Cell RNA - PC-3 [nTPM]":"28.5","Cell RNA - REH [nTPM]":"11.6","Cell RNA - RH-30 [nTPM]":"9.8","Cell RNA - RPMI-8226 [nTPM]":"13.5","Cell RNA - RPTEC TERT1 [nTPM]":"8.6","Cell RNA - RT4 [nTPM]":"21.8","Cell RNA - SCLC-21H [nTPM]":"17.3","Cell RNA - SH-SY5Y [nTPM]":"9.6","Cell RNA - SiHa [nTPM]":"13.6","Cell RNA - SK-BR-3 [nTPM]":"18.2","Cell RNA - SK-MEL-30 [nTPM]":"13.4","Cell RNA - SuSa [nTPM]":"10.8","Cell RNA - T-47d [nTPM]":"17.0","Cell RNA - THP-1 [nTPM]":"7.9","Cell RNA - TIME [nTPM]":"11.0","Cell RNA - U-138 MG [nTPM]":"8.3","Cell RNA - U-2 OS [nTPM]":"10.0","Cell RNA - U-2197 [nTPM]":"13.6","Cell RNA - U-251 MG [nTPM]":"13.1","Cell RNA - U-266\/70 [nTPM]":"8.1","Cell RNA - U-266\/84 [nTPM]":"22.4","Cell RNA - U-698 [nTPM]":"30.3","Cell RNA - U-87 MG [nTPM]":"3.8","Cell RNA - U-937 [nTPM]":"15.9","Cell RNA - WM-115 [nTPM]":"9.2","Blood RNA - basophil [nTPM]":"5.6","Blood RNA - classical monocyte [nTPM]":"2.0","Blood RNA - eosinophil [nTPM]":"1.5","Blood RNA - gdT-cell [nTPM]":"2.0","Blood RNA - intermediate monocyte [nTPM]":"2.2","Blood RNA - MAIT T-cell [nTPM]":"2.7","Blood RNA - memory B-cell [nTPM]":"2.1","Blood RNA - memory CD4 T-cell [nTPM]":"2.2","Blood RNA - memory CD8 T-cell [nTPM]":"2.2","Blood RNA - myeloid DC [nTPM]":"2.6","Blood RNA - naive B-cell [nTPM]":"1.3","Blood RNA - naive CD4 T-cell [nTPM]":"3.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"2.1","Blood RNA - non-classical monocyte [nTPM]":"2.2","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"2.7","Blood RNA - total PBMC [nTPM]":"1.7","Brain RNA - amygdala [nTPM]":"3.1","Brain RNA - basal ganglia [nTPM]":"4.4","Brain RNA - cerebellum [nTPM]":"4.3","Brain RNA - cerebral cortex [nTPM]":"4.6","Brain RNA - hippocampal formation [nTPM]":"3.4","Brain RNA - hypothalamus [nTPM]":"2.9","Brain RNA - medulla oblongata [nTPM]":"2.2","Brain RNA - midbrain [nTPM]":"2.3","Brain RNA - pons [nTPM]":"2.3","Brain RNA - spinal cord [nTPM]":"2.7","Brain RNA - thalamus [nTPM]":"3.2","Brain RNA - white matter [nTPM]":"3.6","Single Cell Type RNA - Adipocytes [nTPM]":"2.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.2","Single Cell Type RNA - Astrocytes [nTPM]":"14.4","Single Cell Type RNA - B-cells [nTPM]":"4.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"6.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"7.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.0","Single Cell Type RNA - dendritic cells [nTPM]":"3.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.1","Single Cell Type RNA - Early spermatids [nTPM]":"7.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.0","Single Cell Type RNA - Endothelial cells [nTPM]":"3.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.3","Single Cell Type RNA - Fibroblasts [nTPM]":"4.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.9","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"4.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"11.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.1","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.6","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"5.2","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"2.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.4","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"22.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.8","Single Cell Type RNA - Paneth cells [nTPM]":"1.1","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"4.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.1","Single Cell Type RNA - Spermatocytes [nTPM]":"16.5","Single Cell Type RNA - Spermatogonia [nTPM]":"10.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.4","Single Cell Type RNA - T-cells [nTPM]":"4.1","Single Cell Type RNA - Theca cells [nTPM]":"7.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.1","Single Cell Type RNA - Urothelial cells [nTPM]":"1.2"},{"Gene":"POMGNT2","Gene synonym":["AGO61","C3orf39","FLJ14566","GTDC2"],"Ensembl":"ENSG00000144647","Gene description":"Protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)","Uniprot":["Q8NAT1"],"Chromosome":"3","Position":"43079232-43106079","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital muscular dystrophy","Disease variant","Dystroglycanopathy","Limb-girdle muscular dystrophy","Lissencephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034870","HPA040989"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA034870":"AB_10602701","HPA040989":"AB_2677238"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.13e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.26e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.00e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Tissue RNA - adipose tissue [nTPM]":"11.0","Tissue RNA - adrenal gland [nTPM]":"13.5","Tissue RNA - amygdala [nTPM]":"22.1","Tissue RNA - appendix [nTPM]":"4.2","Tissue RNA - basal ganglia [nTPM]":"21.0","Tissue RNA - bone marrow [nTPM]":"20.7","Tissue RNA - breast [nTPM]":"9.9","Tissue RNA - cerebellum [nTPM]":"22.6","Tissue RNA - cerebral cortex [nTPM]":"23.1","Tissue RNA - cervix [nTPM]":"19.4","Tissue RNA - choroid plexus [nTPM]":"19.8","Tissue RNA - colon [nTPM]":"14.9","Tissue RNA - duodenum [nTPM]":"3.6","Tissue RNA - endometrium 1 [nTPM]":"50.7","Tissue RNA - epididymis [nTPM]":"11.3","Tissue RNA - esophagus [nTPM]":"7.5","Tissue RNA - fallopian tube [nTPM]":"30.9","Tissue RNA - gallbladder [nTPM]":"9.0","Tissue RNA - heart muscle [nTPM]":"19.1","Tissue RNA - hippocampal formation [nTPM]":"22.6","Tissue RNA - hypothalamus [nTPM]":"20.8","Tissue RNA - kidney [nTPM]":"12.8","Tissue RNA - liver [nTPM]":"9.2","Tissue RNA - lung [nTPM]":"10.2","Tissue RNA - lymph node [nTPM]":"3.1","Tissue RNA - medulla oblongata [nTPM]":"21.7","Tissue RNA - midbrain [nTPM]":"21.0","Tissue RNA - ovary [nTPM]":"30.4","Tissue RNA - pancreas [nTPM]":"15.3","Tissue RNA - parathyroid gland [nTPM]":"17.7","Tissue RNA - pituitary gland [nTPM]":"19.1","Tissue RNA - placenta [nTPM]":"5.5","Tissue RNA - pons [nTPM]":"24.9","Tissue RNA - prostate [nTPM]":"15.2","Tissue RNA - rectum [nTPM]":"2.9","Tissue RNA - retina [nTPM]":"9.0","Tissue RNA - salivary gland [nTPM]":"13.8","Tissue RNA - seminal vesicle [nTPM]":"14.5","Tissue RNA - skeletal muscle [nTPM]":"31.5","Tissue RNA - skin 1 [nTPM]":"11.7","Tissue RNA - small intestine [nTPM]":"7.1","Tissue RNA - smooth muscle [nTPM]":"19.7","Tissue RNA - spinal cord [nTPM]":"18.1","Tissue RNA - spleen [nTPM]":"6.0","Tissue RNA - stomach 1 [nTPM]":"13.8","Tissue RNA - testis [nTPM]":"14.8","Tissue RNA - thalamus [nTPM]":"26.7","Tissue RNA - thymus [nTPM]":"5.5","Tissue RNA - thyroid gland [nTPM]":"11.8","Tissue RNA - tongue [nTPM]":"18.6","Tissue RNA - tonsil [nTPM]":"2.3","Tissue RNA - urinary bladder [nTPM]":"15.2","Tissue RNA - vagina [nTPM]":"13.6","Tissue RNA - white matter [nTPM]":"17.8","Cell RNA - A-431 [nTPM]":"20.0","Cell RNA - A549 [nTPM]":"14.9","Cell RNA - AF22 [nTPM]":"8.5","Cell RNA - AN3-CA [nTPM]":"26.0","Cell RNA - ASC diff [nTPM]":"32.0","Cell RNA - ASC TERT1 [nTPM]":"8.2","Cell RNA - BEWO [nTPM]":"13.5","Cell RNA - BJ [nTPM]":"5.6","Cell RNA - BJ hTERT+ [nTPM]":"10.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"22.7","Cell RNA - CACO-2 [nTPM]":"18.2","Cell RNA - CAPAN-2 [nTPM]":"13.7","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"20.6","Cell RNA - fHDF\/TERT166 [nTPM]":"10.2","Cell RNA - GAMG [nTPM]":"23.6","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"14.0","Cell RNA - HBEC3-KT [nTPM]":"16.3","Cell RNA - HBF TERT88 [nTPM]":"8.5","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"39.2","Cell RNA - HEL [nTPM]":"14.0","Cell RNA - HeLa [nTPM]":"11.1","Cell RNA - Hep G2 [nTPM]":"17.4","Cell RNA - HHSteC [nTPM]":"12.1","Cell RNA - HL-60 [nTPM]":"9.9","Cell RNA - HMC-1 [nTPM]":"15.9","Cell RNA - HSkMC [nTPM]":"9.5","Cell RNA - hTCEpi [nTPM]":"11.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.2","Cell RNA - hTERT-HME1 [nTPM]":"7.7","Cell RNA - hTERT-RPE1 [nTPM]":"7.7","Cell RNA - HUVEC TERT2 [nTPM]":"7.6","Cell RNA - JURKAT [nTPM]":"29.7","Cell RNA - K-562 [nTPM]":"11.6","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"7.6","Cell RNA - MCF7 [nTPM]":"11.8","Cell RNA - MOLT-4 [nTPM]":"18.1","Cell RNA - NB-4 [nTPM]":"2.6","Cell RNA - NTERA-2 [nTPM]":"18.7","Cell RNA - OE19 [nTPM]":"12.4","Cell RNA - PC-3 [nTPM]":"27.7","Cell RNA - REH [nTPM]":"7.0","Cell RNA - RH-30 [nTPM]":"6.0","Cell RNA - RPMI-8226 [nTPM]":"12.3","Cell RNA - RPTEC TERT1 [nTPM]":"11.6","Cell RNA - RT4 [nTPM]":"14.4","Cell RNA - SCLC-21H [nTPM]":"13.4","Cell RNA - SH-SY5Y [nTPM]":"12.2","Cell RNA - SiHa [nTPM]":"11.8","Cell RNA - SK-BR-3 [nTPM]":"9.4","Cell RNA - SK-MEL-30 [nTPM]":"10.9","Cell RNA - SuSa [nTPM]":"5.7","Cell RNA - T-47d [nTPM]":"17.8","Cell RNA - THP-1 [nTPM]":"8.6","Cell RNA - TIME [nTPM]":"3.6","Cell RNA - U-138 MG [nTPM]":"15.7","Cell RNA - U-2 OS [nTPM]":"21.9","Cell RNA - U-2197 [nTPM]":"23.3","Cell RNA - U-251 MG [nTPM]":"23.3","Cell RNA - U-266\/70 [nTPM]":"14.5","Cell RNA - U-266\/84 [nTPM]":"23.2","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"20.2","Cell RNA - U-937 [nTPM]":"19.6","Cell RNA - WM-115 [nTPM]":"17.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"3.0","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"2.7","Blood RNA - memory B-cell [nTPM]":"1.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.9","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"0.9","Blood RNA - naive CD4 T-cell [nTPM]":"2.3","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.0","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"1.7","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"22.1","Brain RNA - basal ganglia [nTPM]":"21.0","Brain RNA - cerebellum [nTPM]":"22.6","Brain RNA - cerebral cortex [nTPM]":"23.1","Brain RNA - hippocampal formation [nTPM]":"22.6","Brain RNA - hypothalamus [nTPM]":"20.8","Brain RNA - medulla oblongata [nTPM]":"21.7","Brain RNA - midbrain [nTPM]":"21.0","Brain RNA - pons [nTPM]":"24.9","Brain RNA - spinal cord [nTPM]":"18.1","Brain RNA - thalamus [nTPM]":"26.7","Brain RNA - white matter [nTPM]":"17.8","Single Cell Type RNA - Adipocytes [nTPM]":"4.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.0","Single Cell Type RNA - Astrocytes [nTPM]":"11.8","Single Cell Type RNA - B-cells [nTPM]":"2.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"15.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"3.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - dendritic cells [nTPM]":"3.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.9","Single Cell Type RNA - Early spermatids [nTPM]":"10.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.6","Single Cell Type RNA - Endothelial cells [nTPM]":"3.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"28.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.3","Single Cell Type RNA - Fibroblasts [nTPM]":"14.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"12.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"6.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.2","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.9","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"4.2","Single Cell Type RNA - Langerhans cells [nTPM]":"4.8","Single Cell Type RNA - Late spermatids [nTPM]":"24.5","Single Cell Type RNA - Leydig cells [nTPM]":"19.9","Single Cell Type RNA - Macrophages [nTPM]":"3.7","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"1.1","Single Cell Type RNA - Muller glia cells [nTPM]":"10.1","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.5","Single Cell Type RNA - Paneth cells [nTPM]":"2.0","Single Cell Type RNA - Peritubular cells [nTPM]":"29.3","Single Cell Type RNA - Plasma cells [nTPM]":"3.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.3","Single Cell Type RNA - Spermatocytes [nTPM]":"10.0","Single Cell Type RNA - Spermatogonia [nTPM]":"19.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.8","Single Cell Type RNA - T-cells [nTPM]":"3.6","Single Cell Type RNA - Theca cells [nTPM]":"3.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.7","Single Cell Type RNA - Urothelial cells [nTPM]":"2.2"},{"Gene":"POMK","Gene synonym":["FLJ23356","SgK196"],"Ensembl":"ENSG00000185900","Gene description":"Protein O-mannose kinase","Uniprot":["Q9H5K3"],"Chromosome":"8","Position":"43093498-43131180","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":["Congenital muscular dystrophy","Disease variant","Dystroglycanopathy","Limb-girdle muscular dystrophy","Lissencephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"14.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"6.9","Inhibitory neurons":"6.8","Microglial cells":"7.5","Oligodendrocyte precursor cells":"5.5","Oligodendrocytes":"6.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013321"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA013321":"AB_2668809"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.3","Tissue RNA - adrenal gland [nTPM]":"2.8","Tissue RNA - amygdala [nTPM]":"11.6","Tissue RNA - appendix [nTPM]":"2.5","Tissue RNA - basal ganglia [nTPM]":"12.6","Tissue RNA - bone marrow [nTPM]":"6.8","Tissue RNA - breast [nTPM]":"3.8","Tissue RNA - cerebellum [nTPM]":"6.0","Tissue RNA - cerebral cortex [nTPM]":"14.5","Tissue RNA - cervix [nTPM]":"4.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"3.3","Tissue RNA - duodenum [nTPM]":"1.6","Tissue RNA - endometrium 1 [nTPM]":"2.3","Tissue RNA - epididymis [nTPM]":"7.2","Tissue RNA - esophagus [nTPM]":"1.9","Tissue RNA - fallopian tube [nTPM]":"2.4","Tissue RNA - gallbladder [nTPM]":"1.9","Tissue RNA - heart muscle [nTPM]":"1.3","Tissue RNA - hippocampal formation [nTPM]":"12.3","Tissue RNA - hypothalamus [nTPM]":"7.9","Tissue RNA - kidney [nTPM]":"2.0","Tissue RNA - liver [nTPM]":"3.3","Tissue RNA - lung [nTPM]":"2.6","Tissue RNA - lymph node [nTPM]":"4.0","Tissue RNA - medulla oblongata [nTPM]":"8.8","Tissue RNA - midbrain [nTPM]":"7.6","Tissue RNA - ovary [nTPM]":"2.6","Tissue RNA - pancreas [nTPM]":"3.3","Tissue RNA - parathyroid gland [nTPM]":"2.6","Tissue RNA - pituitary gland [nTPM]":"0.9","Tissue RNA - placenta [nTPM]":"3.1","Tissue RNA - pons [nTPM]":"9.1","Tissue RNA - prostate [nTPM]":"5.0","Tissue RNA - rectum [nTPM]":"3.6","Tissue RNA - retina [nTPM]":"5.9","Tissue RNA - salivary gland [nTPM]":"2.4","Tissue RNA - seminal vesicle [nTPM]":"2.4","Tissue RNA - skeletal muscle [nTPM]":"2.8","Tissue RNA - skin 1 [nTPM]":"5.8","Tissue RNA - small intestine [nTPM]":"1.8","Tissue RNA - smooth muscle [nTPM]":"2.6","Tissue RNA - spinal cord [nTPM]":"6.1","Tissue RNA - spleen [nTPM]":"3.9","Tissue RNA - stomach 1 [nTPM]":"3.2","Tissue RNA - testis [nTPM]":"3.6","Tissue RNA - thalamus [nTPM]":"11.1","Tissue RNA - thymus [nTPM]":"4.9","Tissue RNA - thyroid gland [nTPM]":"3.1","Tissue RNA - tongue [nTPM]":"2.7","Tissue RNA - tonsil [nTPM]":"4.1","Tissue RNA - urinary bladder [nTPM]":"2.7","Tissue RNA - vagina [nTPM]":"0.8","Tissue RNA - white matter [nTPM]":"8.8","Cell RNA - A-431 [nTPM]":"7.8","Cell RNA - A549 [nTPM]":"9.1","Cell RNA - AF22 [nTPM]":"9.2","Cell RNA - AN3-CA [nTPM]":"24.4","Cell RNA - ASC diff [nTPM]":"8.8","Cell RNA - ASC TERT1 [nTPM]":"6.6","Cell RNA - BEWO [nTPM]":"9.1","Cell RNA - BJ [nTPM]":"4.3","Cell RNA - BJ hTERT+ [nTPM]":"4.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.1","Cell RNA - CACO-2 [nTPM]":"8.4","Cell RNA - CAPAN-2 [nTPM]":"13.8","Cell RNA - Daudi [nTPM]":"9.2","Cell RNA - EFO-21 [nTPM]":"7.7","Cell RNA - fHDF\/TERT166 [nTPM]":"7.1","Cell RNA - GAMG [nTPM]":"2.5","Cell RNA - HaCaT [nTPM]":"8.2","Cell RNA - HAP1 [nTPM]":"13.5","Cell RNA - HBEC3-KT [nTPM]":"11.7","Cell RNA - HBF TERT88 [nTPM]":"7.9","Cell RNA - HDLM-2 [nTPM]":"2.0","Cell RNA - HEK 293 [nTPM]":"4.3","Cell RNA - HEL [nTPM]":"19.2","Cell RNA - HeLa [nTPM]":"6.2","Cell RNA - Hep G2 [nTPM]":"15.6","Cell RNA - HHSteC [nTPM]":"8.3","Cell RNA - HL-60 [nTPM]":"6.1","Cell RNA - HMC-1 [nTPM]":"9.9","Cell RNA - HSkMC [nTPM]":"8.7","Cell RNA - hTCEpi [nTPM]":"15.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.1","Cell RNA - hTERT-HME1 [nTPM]":"10.8","Cell RNA - hTERT-RPE1 [nTPM]":"4.6","Cell RNA - HUVEC TERT2 [nTPM]":"9.1","Cell RNA - JURKAT [nTPM]":"10.1","Cell RNA - K-562 [nTPM]":"4.6","Cell RNA - Karpas-707 [nTPM]":"15.9","Cell RNA - LHCN-M2 [nTPM]":"9.7","Cell RNA - MCF7 [nTPM]":"5.3","Cell RNA - MOLT-4 [nTPM]":"14.5","Cell RNA - NB-4 [nTPM]":"18.6","Cell RNA - NTERA-2 [nTPM]":"19.8","Cell RNA - OE19 [nTPM]":"11.2","Cell RNA - PC-3 [nTPM]":"1.7","Cell RNA - REH [nTPM]":"8.7","Cell RNA - RH-30 [nTPM]":"10.2","Cell RNA - RPMI-8226 [nTPM]":"4.1","Cell RNA - RPTEC TERT1 [nTPM]":"19.1","Cell RNA - RT4 [nTPM]":"11.3","Cell RNA - SCLC-21H [nTPM]":"6.5","Cell RNA - SH-SY5Y [nTPM]":"8.2","Cell RNA - SiHa [nTPM]":"12.4","Cell RNA - SK-BR-3 [nTPM]":"7.5","Cell RNA - SK-MEL-30 [nTPM]":"10.0","Cell RNA - SuSa [nTPM]":"10.7","Cell RNA - T-47d [nTPM]":"14.9","Cell RNA - THP-1 [nTPM]":"9.6","Cell RNA - TIME [nTPM]":"9.8","Cell RNA - U-138 MG [nTPM]":"11.6","Cell RNA - U-2 OS [nTPM]":"12.8","Cell RNA - U-2197 [nTPM]":"11.8","Cell RNA - U-251 MG [nTPM]":"8.1","Cell RNA - U-266\/70 [nTPM]":"5.8","Cell RNA - U-266\/84 [nTPM]":"11.6","Cell RNA - U-698 [nTPM]":"11.7","Cell RNA - U-87 MG [nTPM]":"5.7","Cell RNA - U-937 [nTPM]":"6.3","Cell RNA - WM-115 [nTPM]":"16.0","Blood RNA - basophil [nTPM]":"2.2","Blood RNA - classical monocyte [nTPM]":"0.9","Blood RNA - eosinophil [nTPM]":"0.8","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"0.9","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.1","Blood RNA - neutrophil [nTPM]":"2.8","Blood RNA - NK-cell [nTPM]":"0.9","Blood RNA - non-classical monocyte [nTPM]":"1.5","Blood RNA - plasmacytoid DC [nTPM]":"2.4","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"11.6","Brain RNA - basal ganglia [nTPM]":"12.6","Brain RNA - cerebellum [nTPM]":"6.0","Brain RNA - cerebral cortex [nTPM]":"14.5","Brain RNA - hippocampal formation [nTPM]":"12.3","Brain RNA - hypothalamus [nTPM]":"7.9","Brain RNA - medulla oblongata [nTPM]":"8.8","Brain RNA - midbrain [nTPM]":"7.6","Brain RNA - pons [nTPM]":"9.1","Brain RNA - spinal cord [nTPM]":"6.1","Brain RNA - thalamus [nTPM]":"11.1","Brain RNA - white matter [nTPM]":"8.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"2.9","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"1.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"1.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.9","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.8","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"1.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"0.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"POMT1","Gene synonym":["LGMD2K"],"Ensembl":"ENSG00000130714","Gene description":"Protein O-mannosyltransferase 1","Uniprot":["Q9Y6A1"],"Chromosome":"9","Position":"131502789-131523806","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital muscular dystrophy","Disease variant","Dystroglycanopathy","Limb-girdle muscular dystrophy","Lissencephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"64.5","Spermatocytes":"71.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065252"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA065252":"AB_2685445"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.90e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.68e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Tissue RNA - adipose tissue [nTPM]":"15.7","Tissue RNA - adrenal gland [nTPM]":"20.9","Tissue RNA - amygdala [nTPM]":"16.6","Tissue RNA - appendix [nTPM]":"7.6","Tissue RNA - basal ganglia [nTPM]":"16.7","Tissue RNA - bone marrow [nTPM]":"6.6","Tissue RNA - breast [nTPM]":"16.2","Tissue RNA - cerebellum [nTPM]":"18.4","Tissue RNA - cerebral cortex [nTPM]":"21.0","Tissue RNA - cervix [nTPM]":"21.1","Tissue RNA - choroid plexus [nTPM]":"15.0","Tissue RNA - colon [nTPM]":"24.8","Tissue RNA - duodenum [nTPM]":"9.0","Tissue RNA - endometrium 1 [nTPM]":"17.1","Tissue RNA - epididymis [nTPM]":"7.2","Tissue RNA - esophagus [nTPM]":"15.2","Tissue RNA - fallopian tube [nTPM]":"18.4","Tissue RNA - gallbladder [nTPM]":"9.3","Tissue RNA - heart muscle [nTPM]":"24.5","Tissue RNA - hippocampal formation [nTPM]":"25.5","Tissue RNA - hypothalamus [nTPM]":"16.0","Tissue RNA - kidney [nTPM]":"25.5","Tissue RNA - liver [nTPM]":"24.4","Tissue RNA - lung [nTPM]":"15.6","Tissue RNA - lymph node [nTPM]":"8.3","Tissue RNA - medulla oblongata [nTPM]":"16.0","Tissue RNA - midbrain [nTPM]":"16.2","Tissue RNA - ovary [nTPM]":"25.6","Tissue RNA - pancreas [nTPM]":"25.9","Tissue RNA - parathyroid gland [nTPM]":"15.5","Tissue RNA - pituitary gland [nTPM]":"31.3","Tissue RNA - placenta [nTPM]":"9.7","Tissue RNA - pons [nTPM]":"16.5","Tissue RNA - prostate [nTPM]":"28.4","Tissue RNA - rectum [nTPM]":"6.5","Tissue RNA - retina [nTPM]":"8.1","Tissue RNA - salivary gland [nTPM]":"20.1","Tissue RNA - seminal vesicle [nTPM]":"8.7","Tissue RNA - skeletal muscle [nTPM]":"32.9","Tissue RNA - skin 1 [nTPM]":"17.5","Tissue RNA - small intestine [nTPM]":"19.9","Tissue RNA - smooth muscle [nTPM]":"7.1","Tissue RNA - spinal cord [nTPM]":"14.2","Tissue RNA - spleen [nTPM]":"22.2","Tissue RNA - stomach 1 [nTPM]":"20.4","Tissue RNA - testis [nTPM]":"63.7","Tissue RNA - thalamus [nTPM]":"16.9","Tissue RNA - thymus [nTPM]":"7.1","Tissue RNA - thyroid gland [nTPM]":"19.0","Tissue RNA - tongue [nTPM]":"13.4","Tissue RNA - tonsil [nTPM]":"5.4","Tissue RNA - urinary bladder [nTPM]":"16.5","Tissue RNA - vagina [nTPM]":"17.1","Tissue RNA - white matter [nTPM]":"15.5","Cell RNA - A-431 [nTPM]":"9.8","Cell RNA - A549 [nTPM]":"17.4","Cell RNA - AF22 [nTPM]":"10.5","Cell RNA - AN3-CA [nTPM]":"26.4","Cell RNA - ASC diff [nTPM]":"19.3","Cell RNA - ASC TERT1 [nTPM]":"13.5","Cell RNA - BEWO [nTPM]":"24.5","Cell RNA - BJ [nTPM]":"12.1","Cell RNA - BJ hTERT+ [nTPM]":"17.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.1","Cell RNA - CACO-2 [nTPM]":"15.8","Cell RNA - CAPAN-2 [nTPM]":"14.7","Cell RNA - Daudi [nTPM]":"2.5","Cell RNA - EFO-21 [nTPM]":"16.9","Cell RNA - fHDF\/TERT166 [nTPM]":"26.4","Cell RNA - GAMG [nTPM]":"8.6","Cell RNA - HaCaT [nTPM]":"24.1","Cell RNA - HAP1 [nTPM]":"17.3","Cell RNA - HBEC3-KT [nTPM]":"16.6","Cell RNA - HBF TERT88 [nTPM]":"5.9","Cell RNA - HDLM-2 [nTPM]":"16.2","Cell RNA - HEK 293 [nTPM]":"21.6","Cell RNA - HEL [nTPM]":"4.2","Cell RNA - HeLa [nTPM]":"28.5","Cell RNA - Hep G2 [nTPM]":"7.8","Cell RNA - HHSteC [nTPM]":"23.1","Cell RNA - HL-60 [nTPM]":"13.1","Cell RNA - HMC-1 [nTPM]":"10.5","Cell RNA - HSkMC [nTPM]":"10.8","Cell RNA - hTCEpi [nTPM]":"10.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.3","Cell RNA - hTERT-HME1 [nTPM]":"5.0","Cell RNA - hTERT-RPE1 [nTPM]":"17.6","Cell RNA - HUVEC TERT2 [nTPM]":"15.1","Cell RNA - JURKAT [nTPM]":"16.4","Cell RNA - K-562 [nTPM]":"13.4","Cell RNA - Karpas-707 [nTPM]":"15.6","Cell RNA - LHCN-M2 [nTPM]":"23.2","Cell RNA - MCF7 [nTPM]":"27.6","Cell RNA - MOLT-4 [nTPM]":"15.8","Cell RNA - NB-4 [nTPM]":"25.2","Cell RNA - NTERA-2 [nTPM]":"6.7","Cell RNA - OE19 [nTPM]":"9.6","Cell RNA - PC-3 [nTPM]":"21.1","Cell RNA - REH [nTPM]":"15.7","Cell RNA - RH-30 [nTPM]":"13.8","Cell RNA - RPMI-8226 [nTPM]":"24.6","Cell RNA - RPTEC TERT1 [nTPM]":"18.1","Cell RNA - RT4 [nTPM]":"1.5","Cell RNA - SCLC-21H [nTPM]":"15.0","Cell RNA - SH-SY5Y [nTPM]":"14.1","Cell RNA - SiHa [nTPM]":"25.1","Cell RNA - SK-BR-3 [nTPM]":"26.8","Cell RNA - SK-MEL-30 [nTPM]":"13.0","Cell RNA - SuSa [nTPM]":"5.8","Cell RNA - T-47d [nTPM]":"31.4","Cell RNA - THP-1 [nTPM]":"17.7","Cell RNA - TIME [nTPM]":"20.9","Cell RNA - U-138 MG [nTPM]":"13.8","Cell RNA - U-2 OS [nTPM]":"2.2","Cell RNA - U-2197 [nTPM]":"28.6","Cell RNA - U-251 MG [nTPM]":"10.3","Cell RNA - U-266\/70 [nTPM]":"7.3","Cell RNA - U-266\/84 [nTPM]":"7.0","Cell RNA - U-698 [nTPM]":"5.2","Cell RNA - U-87 MG [nTPM]":"8.7","Cell RNA - U-937 [nTPM]":"29.1","Cell RNA - WM-115 [nTPM]":"13.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.8","Blood RNA - eosinophil [nTPM]":"3.4","Blood RNA - gdT-cell [nTPM]":"5.2","Blood RNA - intermediate monocyte [nTPM]":"3.0","Blood RNA - MAIT T-cell [nTPM]":"7.7","Blood RNA - memory B-cell [nTPM]":"1.9","Blood RNA - memory CD4 T-cell [nTPM]":"5.0","Blood RNA - memory CD8 T-cell [nTPM]":"5.3","Blood RNA - myeloid DC [nTPM]":"4.0","Blood RNA - naive B-cell [nTPM]":"2.6","Blood RNA - naive CD4 T-cell [nTPM]":"4.8","Blood RNA - naive CD8 T-cell [nTPM]":"3.6","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"3.2","Blood RNA - non-classical monocyte [nTPM]":"2.9","Blood RNA - plasmacytoid DC [nTPM]":"2.4","Blood RNA - T-reg [nTPM]":"5.2","Blood RNA - total PBMC [nTPM]":"4.0","Brain RNA - amygdala [nTPM]":"16.6","Brain RNA - basal ganglia [nTPM]":"16.7","Brain RNA - cerebellum [nTPM]":"18.4","Brain RNA - cerebral cortex [nTPM]":"21.0","Brain RNA - hippocampal formation [nTPM]":"25.5","Brain RNA - hypothalamus [nTPM]":"16.0","Brain RNA - medulla oblongata [nTPM]":"16.0","Brain RNA - midbrain [nTPM]":"16.2","Brain RNA - pons [nTPM]":"16.5","Brain RNA - spinal cord [nTPM]":"14.2","Brain RNA - thalamus [nTPM]":"16.9","Brain RNA - white matter [nTPM]":"15.5","Single Cell Type RNA - Adipocytes [nTPM]":"5.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.0","Single Cell Type RNA - Astrocytes [nTPM]":"18.6","Single Cell Type RNA - B-cells [nTPM]":"7.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"13.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"8.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.8","Single Cell Type RNA - dendritic cells [nTPM]":"6.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"10.7","Single Cell Type RNA - Early spermatids [nTPM]":"64.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.3","Single Cell Type RNA - Endothelial cells [nTPM]":"8.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.8","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"21.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.9","Single Cell Type RNA - Fibroblasts [nTPM]":"9.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.9","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"15.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"10.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.8","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.4","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.4","Single Cell Type RNA - Langerhans cells [nTPM]":"5.9","Single Cell Type RNA - Late spermatids [nTPM]":"33.0","Single Cell Type RNA - Leydig cells [nTPM]":"8.7","Single Cell Type RNA - Macrophages [nTPM]":"5.6","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"7.5","Single Cell Type RNA - Muller glia cells [nTPM]":"12.3","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.1","Single Cell Type RNA - Paneth cells [nTPM]":"6.0","Single Cell Type RNA - Peritubular cells [nTPM]":"10.1","Single Cell Type RNA - Plasma cells [nTPM]":"6.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.2","Single Cell Type RNA - Spermatocytes [nTPM]":"71.6","Single Cell Type RNA - Spermatogonia [nTPM]":"9.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.5","Single Cell Type RNA - T-cells [nTPM]":"9.0","Single Cell Type RNA - Theca cells [nTPM]":"6.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.1","Single Cell Type RNA - Urothelial cells [nTPM]":"2.6"},{"Gene":"POMT2","Gene synonym":["LGMD2N"],"Ensembl":"ENSG00000009830","Gene description":"Protein O-mannosyltransferase 2","Uniprot":["Q9UKY4"],"Chromosome":"14","Position":"77274956-77320883","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital muscular dystrophy","Dystroglycanopathy","Limb-girdle muscular dystrophy","Lissencephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"37.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"27.1","Oligodendrocytes":"30.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003663"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli","Cytosol"],"Antibody RRID":{"HPA003663":"AB_1079655"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.40e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.8","Tissue RNA - adrenal gland [nTPM]":"12.4","Tissue RNA - amygdala [nTPM]":"13.2","Tissue RNA - appendix [nTPM]":"4.1","Tissue RNA - basal ganglia [nTPM]":"14.9","Tissue RNA - bone marrow [nTPM]":"2.5","Tissue RNA - breast [nTPM]":"5.7","Tissue RNA - cerebellum [nTPM]":"13.5","Tissue RNA - cerebral cortex [nTPM]":"13.4","Tissue RNA - cervix [nTPM]":"8.0","Tissue RNA - choroid plexus [nTPM]":"12.5","Tissue RNA - colon [nTPM]":"6.7","Tissue RNA - duodenum [nTPM]":"2.6","Tissue RNA - endometrium 1 [nTPM]":"6.7","Tissue RNA - epididymis [nTPM]":"9.8","Tissue RNA - esophagus [nTPM]":"5.5","Tissue RNA - fallopian tube [nTPM]":"5.8","Tissue RNA - gallbladder [nTPM]":"4.0","Tissue RNA - heart muscle [nTPM]":"7.9","Tissue RNA - hippocampal formation [nTPM]":"12.7","Tissue RNA - hypothalamus [nTPM]":"13.1","Tissue RNA - kidney [nTPM]":"10.8","Tissue RNA - liver [nTPM]":"9.3","Tissue RNA - lung [nTPM]":"5.6","Tissue RNA - lymph node [nTPM]":"1.8","Tissue RNA - medulla oblongata [nTPM]":"14.6","Tissue RNA - midbrain [nTPM]":"14.6","Tissue RNA - ovary [nTPM]":"6.1","Tissue RNA - pancreas [nTPM]":"8.8","Tissue RNA - parathyroid gland [nTPM]":"8.6","Tissue RNA - pituitary gland [nTPM]":"12.6","Tissue RNA - placenta [nTPM]":"7.0","Tissue RNA - pons [nTPM]":"13.4","Tissue RNA - prostate [nTPM]":"7.8","Tissue RNA - rectum [nTPM]":"3.3","Tissue RNA - retina [nTPM]":"5.6","Tissue RNA - salivary gland [nTPM]":"6.3","Tissue RNA - seminal vesicle [nTPM]":"6.9","Tissue RNA - skeletal muscle [nTPM]":"19.1","Tissue RNA - skin 1 [nTPM]":"4.7","Tissue RNA - small intestine [nTPM]":"4.9","Tissue RNA - smooth muscle [nTPM]":"4.6","Tissue RNA - spinal cord [nTPM]":"13.7","Tissue RNA - spleen [nTPM]":"5.6","Tissue RNA - stomach 1 [nTPM]":"5.9","Tissue RNA - testis [nTPM]":"37.5","Tissue RNA - thalamus [nTPM]":"14.4","Tissue RNA - thymus [nTPM]":"2.9","Tissue RNA - thyroid gland [nTPM]":"10.9","Tissue RNA - tongue [nTPM]":"8.4","Tissue RNA - tonsil [nTPM]":"1.9","Tissue RNA - urinary bladder [nTPM]":"7.9","Tissue RNA - vagina [nTPM]":"5.3","Tissue RNA - white matter [nTPM]":"15.4","Cell RNA - A-431 [nTPM]":"15.6","Cell RNA - A549 [nTPM]":"19.4","Cell RNA - AF22 [nTPM]":"18.6","Cell RNA - AN3-CA [nTPM]":"21.1","Cell RNA - ASC diff [nTPM]":"13.0","Cell RNA - ASC TERT1 [nTPM]":"10.3","Cell RNA - BEWO [nTPM]":"14.8","Cell RNA - BJ [nTPM]":"13.4","Cell RNA - BJ hTERT+ [nTPM]":"10.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.6","Cell RNA - CACO-2 [nTPM]":"9.6","Cell RNA - CAPAN-2 [nTPM]":"13.6","Cell RNA - Daudi [nTPM]":"4.6","Cell RNA - EFO-21 [nTPM]":"10.6","Cell RNA - fHDF\/TERT166 [nTPM]":"12.6","Cell RNA - GAMG [nTPM]":"27.1","Cell RNA - HaCaT [nTPM]":"17.1","Cell RNA - HAP1 [nTPM]":"8.8","Cell RNA - HBEC3-KT [nTPM]":"13.3","Cell RNA - HBF TERT88 [nTPM]":"13.5","Cell RNA - HDLM-2 [nTPM]":"6.9","Cell RNA - HEK 293 [nTPM]":"12.1","Cell RNA - HEL [nTPM]":"2.8","Cell RNA - HeLa [nTPM]":"8.9","Cell RNA - Hep G2 [nTPM]":"7.9","Cell RNA - HHSteC [nTPM]":"15.8","Cell RNA - HL-60 [nTPM]":"3.2","Cell RNA - HMC-1 [nTPM]":"8.9","Cell RNA - HSkMC [nTPM]":"10.5","Cell RNA - hTCEpi [nTPM]":"13.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.3","Cell RNA - hTERT-HME1 [nTPM]":"17.8","Cell RNA - hTERT-RPE1 [nTPM]":"13.6","Cell RNA - HUVEC TERT2 [nTPM]":"11.5","Cell RNA - JURKAT [nTPM]":"4.5","Cell RNA - K-562 [nTPM]":"7.4","Cell RNA - Karpas-707 [nTPM]":"10.5","Cell RNA - LHCN-M2 [nTPM]":"13.0","Cell RNA - MCF7 [nTPM]":"30.7","Cell RNA - MOLT-4 [nTPM]":"5.4","Cell RNA - NB-4 [nTPM]":"15.0","Cell RNA - NTERA-2 [nTPM]":"5.3","Cell RNA - OE19 [nTPM]":"21.4","Cell RNA - PC-3 [nTPM]":"16.2","Cell RNA - REH [nTPM]":"5.3","Cell RNA - RH-30 [nTPM]":"18.0","Cell RNA - RPMI-8226 [nTPM]":"4.1","Cell RNA - RPTEC TERT1 [nTPM]":"20.4","Cell RNA - RT4 [nTPM]":"11.3","Cell RNA - SCLC-21H [nTPM]":"15.6","Cell RNA - SH-SY5Y [nTPM]":"15.2","Cell RNA - SiHa [nTPM]":"8.7","Cell RNA - SK-BR-3 [nTPM]":"14.6","Cell RNA - SK-MEL-30 [nTPM]":"11.3","Cell RNA - SuSa [nTPM]":"12.0","Cell RNA - T-47d [nTPM]":"15.1","Cell RNA - THP-1 [nTPM]":"6.5","Cell RNA - TIME [nTPM]":"9.6","Cell RNA - U-138 MG [nTPM]":"14.6","Cell RNA - U-2 OS [nTPM]":"22.8","Cell RNA - U-2197 [nTPM]":"17.1","Cell RNA - U-251 MG [nTPM]":"12.0","Cell RNA - U-266\/70 [nTPM]":"6.8","Cell RNA - U-266\/84 [nTPM]":"14.5","Cell RNA - U-698 [nTPM]":"2.1","Cell RNA - U-87 MG [nTPM]":"7.4","Cell RNA - U-937 [nTPM]":"4.8","Cell RNA - WM-115 [nTPM]":"13.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"13.2","Brain RNA - basal ganglia [nTPM]":"14.9","Brain RNA - cerebellum [nTPM]":"13.5","Brain RNA - cerebral cortex [nTPM]":"13.4","Brain RNA - hippocampal formation [nTPM]":"12.7","Brain RNA - hypothalamus [nTPM]":"13.1","Brain RNA - medulla oblongata [nTPM]":"14.6","Brain RNA - midbrain [nTPM]":"14.6","Brain RNA - pons [nTPM]":"13.4","Brain RNA - spinal cord [nTPM]":"13.7","Brain RNA - thalamus [nTPM]":"14.4","Brain RNA - white matter [nTPM]":"15.4","Single Cell Type RNA - Adipocytes [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.8","Single Cell Type RNA - Astrocytes [nTPM]":"27.1","Single Cell Type RNA - B-cells [nTPM]":"2.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"7.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"1.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"7.6","Single Cell Type RNA - Early spermatids [nTPM]":"14.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.7","Single Cell Type RNA - Endothelial cells [nTPM]":"3.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.2","Single Cell Type RNA - Fibroblasts [nTPM]":"6.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.0","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"6.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"5.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.5","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.2","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.2","Single Cell Type RNA - Langerhans cells [nTPM]":"2.6","Single Cell Type RNA - Late spermatids [nTPM]":"17.2","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"2.4","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"2.3","Single Cell Type RNA - Muller glia cells [nTPM]":"5.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"30.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.5","Single Cell Type RNA - Paneth cells [nTPM]":"3.2","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"2.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.0","Single Cell Type RNA - Spermatocytes [nTPM]":"11.3","Single Cell Type RNA - Spermatogonia [nTPM]":"8.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.7","Single Cell Type RNA - T-cells [nTPM]":"1.2","Single Cell Type RNA - Theca cells [nTPM]":"13.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.6","Single Cell Type RNA - Urothelial cells [nTPM]":"1.9"},{"Gene":"PON1","Gene synonym":["ESA","PON"],"Ensembl":"ENSG00000005421","Gene description":"Paraoxonase 1","Uniprot":["P27169"],"Chromosome":"7","Position":"95297676-95324532","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted secreted proteins","Transporters"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"103","RNA tissue specific nTPM":{"liver":"531.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"23","RNA single cell type specific nTPM":{"Hepatocytes":"440.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"78","RNA cancer specific FPKM":{"liver cancer":"97.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001610"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":96000000000,"Blood concentration - Conc. blood MS [pg\/L]":"17000000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA001610":"AB_1079656"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.24e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"4.1","Tissue RNA - amygdala [nTPM]":"0.6","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"531.8","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.5","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.5","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"5.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.6","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.5","Brain RNA - pons [nTPM]":"0.5","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.5","Single Cell Type RNA - Astrocytes [nTPM]":"7.2","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"13.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.9","Single Cell Type RNA - Hepatocytes [nTPM]":"440.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"13.4","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"POP1","Gene synonym":[],"Ensembl":"ENSG00000104356","Gene description":"POP1 homolog, ribonuclease P\/MRP subunit","Uniprot":["Q99575"],"Chromosome":"8","Position":"98117293-98159835","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["tRNA processing"],"Molecular function":["Hydrolase","RNA-binding"],"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066194"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA066194":"AB_2732742"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.54e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.26e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.88e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.97e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Tissue RNA - adipose tissue [nTPM]":"2.1","Tissue RNA - adrenal gland [nTPM]":"1.6","Tissue RNA - amygdala [nTPM]":"1.7","Tissue RNA - appendix [nTPM]":"3.5","Tissue RNA - basal ganglia [nTPM]":"1.5","Tissue RNA - bone marrow [nTPM]":"1.5","Tissue RNA - breast [nTPM]":"2.1","Tissue RNA - cerebellum [nTPM]":"3.4","Tissue RNA - cerebral cortex [nTPM]":"2.3","Tissue RNA - cervix [nTPM]":"1.4","Tissue RNA - choroid plexus [nTPM]":"1.2","Tissue RNA - colon [nTPM]":"1.9","Tissue RNA - duodenum [nTPM]":"1.5","Tissue RNA - endometrium 1 [nTPM]":"1.7","Tissue RNA - epididymis [nTPM]":"1.4","Tissue RNA - esophagus [nTPM]":"3.0","Tissue RNA - fallopian tube [nTPM]":"1.8","Tissue RNA - gallbladder [nTPM]":"1.3","Tissue RNA - heart muscle [nTPM]":"1.6","Tissue RNA - hippocampal formation [nTPM]":"1.3","Tissue RNA - hypothalamus [nTPM]":"1.2","Tissue RNA - kidney [nTPM]":"2.0","Tissue RNA - liver [nTPM]":"1.9","Tissue RNA - lung [nTPM]":"1.6","Tissue RNA - lymph node [nTPM]":"3.6","Tissue RNA - medulla oblongata [nTPM]":"1.1","Tissue RNA - midbrain [nTPM]":"1.4","Tissue RNA - ovary [nTPM]":"2.9","Tissue RNA - pancreas [nTPM]":"1.7","Tissue RNA - parathyroid gland [nTPM]":"1.7","Tissue RNA - pituitary gland [nTPM]":"1.5","Tissue RNA - placenta [nTPM]":"1.2","Tissue RNA - pons [nTPM]":"1.1","Tissue RNA - prostate [nTPM]":"1.5","Tissue RNA - rectum [nTPM]":"4.8","Tissue RNA - retina [nTPM]":"2.4","Tissue RNA - salivary gland [nTPM]":"1.4","Tissue RNA - seminal vesicle [nTPM]":"1.3","Tissue RNA - skeletal muscle [nTPM]":"1.7","Tissue RNA - skin 1 [nTPM]":"3.0","Tissue RNA - small intestine [nTPM]":"1.6","Tissue RNA - smooth muscle [nTPM]":"1.8","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"2.1","Tissue RNA - stomach 1 [nTPM]":"1.9","Tissue RNA - testis [nTPM]":"3.1","Tissue RNA - thalamus [nTPM]":"1.6","Tissue RNA - thymus [nTPM]":"2.6","Tissue RNA - thyroid gland [nTPM]":"1.5","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"4.4","Tissue RNA - urinary bladder [nTPM]":"2.5","Tissue RNA - vagina [nTPM]":"1.5","Tissue RNA - white matter [nTPM]":"1.8","Cell RNA - A-431 [nTPM]":"21.9","Cell RNA - A549 [nTPM]":"12.9","Cell RNA - AF22 [nTPM]":"13.8","Cell RNA - AN3-CA [nTPM]":"12.8","Cell RNA - ASC diff [nTPM]":"4.8","Cell RNA - ASC TERT1 [nTPM]":"3.3","Cell RNA - BEWO [nTPM]":"9.1","Cell RNA - BJ [nTPM]":"18.3","Cell RNA - BJ hTERT+ [nTPM]":"15.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.8","Cell RNA - CACO-2 [nTPM]":"13.4","Cell RNA - CAPAN-2 [nTPM]":"13.8","Cell RNA - Daudi [nTPM]":"15.3","Cell RNA - EFO-21 [nTPM]":"25.6","Cell RNA - fHDF\/TERT166 [nTPM]":"12.9","Cell RNA - GAMG [nTPM]":"9.0","Cell RNA - HaCaT [nTPM]":"14.3","Cell RNA - HAP1 [nTPM]":"40.3","Cell RNA - HBEC3-KT [nTPM]":"18.2","Cell RNA - HBF TERT88 [nTPM]":"18.9","Cell RNA - HDLM-2 [nTPM]":"11.1","Cell RNA - HEK 293 [nTPM]":"17.0","Cell RNA - HEL [nTPM]":"30.0","Cell RNA - HeLa [nTPM]":"10.2","Cell RNA - Hep G2 [nTPM]":"9.2","Cell RNA - HHSteC [nTPM]":"2.1","Cell RNA - HL-60 [nTPM]":"16.4","Cell RNA - HMC-1 [nTPM]":"18.4","Cell RNA - HSkMC [nTPM]":"2.8","Cell RNA - hTCEpi [nTPM]":"3.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.8","Cell RNA - hTERT-HME1 [nTPM]":"8.2","Cell RNA - hTERT-RPE1 [nTPM]":"5.7","Cell RNA - HUVEC TERT2 [nTPM]":"14.8","Cell RNA - JURKAT [nTPM]":"7.2","Cell RNA - K-562 [nTPM]":"17.0","Cell RNA - Karpas-707 [nTPM]":"13.5","Cell RNA - LHCN-M2 [nTPM]":"17.7","Cell RNA - MCF7 [nTPM]":"17.4","Cell RNA - MOLT-4 [nTPM]":"23.8","Cell RNA - NB-4 [nTPM]":"8.3","Cell RNA - NTERA-2 [nTPM]":"10.4","Cell RNA - OE19 [nTPM]":"25.1","Cell RNA - PC-3 [nTPM]":"17.6","Cell RNA - REH [nTPM]":"19.4","Cell RNA - RH-30 [nTPM]":"7.5","Cell RNA - RPMI-8226 [nTPM]":"11.0","Cell RNA - RPTEC TERT1 [nTPM]":"13.5","Cell RNA - RT4 [nTPM]":"11.5","Cell RNA - SCLC-21H [nTPM]":"32.8","Cell RNA - SH-SY5Y [nTPM]":"7.7","Cell RNA - SiHa [nTPM]":"8.4","Cell RNA - SK-BR-3 [nTPM]":"14.2","Cell RNA - SK-MEL-30 [nTPM]":"6.4","Cell RNA - SuSa [nTPM]":"7.9","Cell RNA - T-47d [nTPM]":"19.2","Cell RNA - THP-1 [nTPM]":"6.0","Cell RNA - TIME [nTPM]":"18.4","Cell RNA - U-138 MG [nTPM]":"16.3","Cell RNA - U-2 OS [nTPM]":"11.6","Cell RNA - U-2197 [nTPM]":"20.8","Cell RNA - U-251 MG [nTPM]":"36.5","Cell RNA - U-266\/70 [nTPM]":"13.3","Cell RNA - U-266\/84 [nTPM]":"13.6","Cell RNA - U-698 [nTPM]":"32.7","Cell RNA - U-87 MG [nTPM]":"12.8","Cell RNA - U-937 [nTPM]":"17.3","Cell RNA - WM-115 [nTPM]":"14.6","Blood RNA - basophil [nTPM]":"9.4","Blood RNA - classical monocyte [nTPM]":"5.1","Blood RNA - eosinophil [nTPM]":"3.9","Blood RNA - gdT-cell [nTPM]":"7.4","Blood RNA - intermediate monocyte [nTPM]":"5.7","Blood RNA - MAIT T-cell [nTPM]":"6.0","Blood RNA - memory B-cell [nTPM]":"4.9","Blood RNA - memory CD4 T-cell [nTPM]":"5.4","Blood RNA - memory CD8 T-cell [nTPM]":"5.0","Blood RNA - myeloid DC [nTPM]":"5.0","Blood RNA - naive B-cell [nTPM]":"8.1","Blood RNA - naive CD4 T-cell [nTPM]":"6.8","Blood RNA - naive CD8 T-cell [nTPM]":"6.5","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"3.8","Blood RNA - non-classical monocyte [nTPM]":"2.9","Blood RNA - plasmacytoid DC [nTPM]":"6.2","Blood RNA - T-reg [nTPM]":"4.9","Blood RNA - total PBMC [nTPM]":"2.1","Brain RNA - amygdala [nTPM]":"1.7","Brain RNA - basal ganglia [nTPM]":"1.5","Brain RNA - cerebellum [nTPM]":"3.4","Brain RNA - cerebral cortex [nTPM]":"2.3","Brain RNA - hippocampal formation [nTPM]":"1.3","Brain RNA - hypothalamus [nTPM]":"1.2","Brain RNA - medulla oblongata [nTPM]":"1.1","Brain RNA - midbrain [nTPM]":"1.4","Brain RNA - pons [nTPM]":"1.1","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"1.6","Brain RNA - white matter [nTPM]":"1.8","Single Cell Type RNA - Adipocytes [nTPM]":"2.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.9","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"4.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"7.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.1","Single Cell Type RNA - dendritic cells [nTPM]":"4.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.8","Single Cell Type RNA - Early spermatids [nTPM]":"13.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.4","Single Cell Type RNA - Endothelial cells [nTPM]":"4.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.4","Single Cell Type RNA - Fibroblasts [nTPM]":"5.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.9","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"5.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"5.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.4","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"19.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.7","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.4","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"3.0","Single Cell Type RNA - Leydig cells [nTPM]":"5.3","Single Cell Type RNA - Macrophages [nTPM]":"3.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"7.9","Single Cell Type RNA - Muller glia cells [nTPM]":"2.7","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.8","Single Cell Type RNA - Paneth cells [nTPM]":"1.0","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"5.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.1","Single Cell Type RNA - Spermatocytes [nTPM]":"7.7","Single Cell Type RNA - Spermatogonia [nTPM]":"19.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.0","Single Cell Type RNA - T-cells [nTPM]":"4.4","Single Cell Type RNA - Theca cells [nTPM]":"6.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.9","Single Cell Type RNA - Urothelial cells [nTPM]":"5.1"},{"Gene":"POR","Gene synonym":["CYPOR","FLJ26468"],"Ensembl":"ENSG00000127948","Gene description":"Cytochrome p450 oxidoreductase","Uniprot":["P16435"],"Chromosome":"7","Position":"75899200-75986855","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Congenital adrenal hyperplasia","Craniosynostosis","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"313.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"489.2","Proximal enterocytes":"274.2","Theca cells":"647.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SK-BR-3":"328.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004372","HPA010136"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB004372":"AB_627391","HPA010136":"AB_1079657"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.54e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-2"},"Tissue RNA - adipose tissue [nTPM]":"53.4","Tissue RNA - adrenal gland [nTPM]":"197.4","Tissue RNA - amygdala [nTPM]":"19.9","Tissue RNA - appendix [nTPM]":"32.1","Tissue RNA - basal ganglia [nTPM]":"20.7","Tissue RNA - bone marrow [nTPM]":"17.9","Tissue RNA - breast [nTPM]":"44.7","Tissue RNA - cerebellum [nTPM]":"14.1","Tissue RNA - cerebral cortex [nTPM]":"18.6","Tissue RNA - cervix [nTPM]":"42.0","Tissue RNA - choroid plexus [nTPM]":"15.5","Tissue RNA - colon [nTPM]":"35.9","Tissue RNA - duodenum [nTPM]":"105.2","Tissue RNA - endometrium 1 [nTPM]":"32.1","Tissue RNA - epididymis [nTPM]":"29.4","Tissue RNA - esophagus [nTPM]":"53.6","Tissue RNA - fallopian tube [nTPM]":"50.2","Tissue RNA - gallbladder [nTPM]":"37.0","Tissue RNA - heart muscle [nTPM]":"43.3","Tissue RNA - hippocampal formation [nTPM]":"20.7","Tissue RNA - hypothalamus [nTPM]":"30.2","Tissue RNA - kidney [nTPM]":"38.1","Tissue RNA - liver [nTPM]":"313.3","Tissue RNA - lung [nTPM]":"55.0","Tissue RNA - lymph node [nTPM]":"19.9","Tissue RNA - medulla oblongata [nTPM]":"22.2","Tissue RNA - midbrain [nTPM]":"24.5","Tissue RNA - ovary [nTPM]":"52.2","Tissue RNA - pancreas [nTPM]":"44.5","Tissue RNA - parathyroid gland [nTPM]":"77.6","Tissue RNA - pituitary gland [nTPM]":"71.4","Tissue RNA - placenta [nTPM]":"46.3","Tissue RNA - pons [nTPM]":"20.9","Tissue RNA - prostate [nTPM]":"31.8","Tissue RNA - rectum [nTPM]":"21.9","Tissue RNA - retina [nTPM]":"12.7","Tissue RNA - salivary gland [nTPM]":"29.9","Tissue RNA - seminal vesicle [nTPM]":"113.1","Tissue RNA - skeletal muscle [nTPM]":"56.2","Tissue RNA - skin 1 [nTPM]":"43.8","Tissue RNA - small intestine [nTPM]":"92.4","Tissue RNA - smooth muscle [nTPM]":"28.2","Tissue RNA - spinal cord [nTPM]":"16.9","Tissue RNA - spleen [nTPM]":"43.8","Tissue RNA - stomach 1 [nTPM]":"41.5","Tissue RNA - testis [nTPM]":"25.5","Tissue RNA - thalamus [nTPM]":"34.7","Tissue RNA - thymus [nTPM]":"38.0","Tissue RNA - thyroid gland [nTPM]":"131.3","Tissue RNA - tongue [nTPM]":"68.1","Tissue RNA - tonsil [nTPM]":"23.2","Tissue RNA - urinary bladder [nTPM]":"36.6","Tissue RNA - vagina [nTPM]":"42.3","Tissue RNA - white matter [nTPM]":"15.3","Cell RNA - A-431 [nTPM]":"59.6","Cell RNA - A549 [nTPM]":"133.0","Cell RNA - AF22 [nTPM]":"57.0","Cell RNA - AN3-CA [nTPM]":"106.3","Cell RNA - ASC diff [nTPM]":"212.9","Cell RNA - ASC TERT1 [nTPM]":"79.8","Cell RNA - BEWO [nTPM]":"98.0","Cell RNA - BJ [nTPM]":"24.4","Cell RNA - BJ hTERT+ [nTPM]":"79.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"44.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"62.3","Cell RNA - CACO-2 [nTPM]":"100.7","Cell RNA - CAPAN-2 [nTPM]":"257.0","Cell RNA - Daudi [nTPM]":"56.1","Cell RNA - EFO-21 [nTPM]":"21.9","Cell RNA - fHDF\/TERT166 [nTPM]":"53.1","Cell RNA - GAMG [nTPM]":"151.8","Cell RNA - HaCaT [nTPM]":"28.3","Cell RNA - HAP1 [nTPM]":"76.0","Cell RNA - HBEC3-KT [nTPM]":"38.4","Cell RNA - HBF TERT88 [nTPM]":"19.6","Cell RNA - HDLM-2 [nTPM]":"48.1","Cell RNA - HEK 293 [nTPM]":"57.9","Cell RNA - HEL [nTPM]":"26.0","Cell RNA - HeLa [nTPM]":"36.9","Cell RNA - Hep G2 [nTPM]":"189.4","Cell RNA - HHSteC [nTPM]":"146.5","Cell RNA - HL-60 [nTPM]":"26.2","Cell RNA - HMC-1 [nTPM]":"45.5","Cell RNA - HSkMC [nTPM]":"163.9","Cell RNA - hTCEpi [nTPM]":"47.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"59.2","Cell RNA - hTERT-HME1 [nTPM]":"43.2","Cell RNA - hTERT-RPE1 [nTPM]":"36.3","Cell RNA - HUVEC TERT2 [nTPM]":"42.3","Cell RNA - JURKAT [nTPM]":"27.1","Cell RNA - K-562 [nTPM]":"79.1","Cell RNA - Karpas-707 [nTPM]":"24.0","Cell RNA - LHCN-M2 [nTPM]":"40.8","Cell RNA - MCF7 [nTPM]":"90.9","Cell RNA - MOLT-4 [nTPM]":"29.0","Cell RNA - NB-4 [nTPM]":"49.4","Cell RNA - NTERA-2 [nTPM]":"71.7","Cell RNA - OE19 [nTPM]":"92.9","Cell RNA - PC-3 [nTPM]":"74.8","Cell RNA - REH [nTPM]":"41.0","Cell RNA - RH-30 [nTPM]":"37.6","Cell RNA - RPMI-8226 [nTPM]":"61.1","Cell RNA - RPTEC TERT1 [nTPM]":"50.0","Cell RNA - RT4 [nTPM]":"72.8","Cell RNA - SCLC-21H [nTPM]":"59.3","Cell RNA - SH-SY5Y [nTPM]":"57.4","Cell RNA - SiHa [nTPM]":"65.4","Cell RNA - SK-BR-3 [nTPM]":"328.4","Cell RNA - SK-MEL-30 [nTPM]":"91.0","Cell RNA - SuSa [nTPM]":"32.6","Cell RNA - T-47d [nTPM]":"94.0","Cell RNA - THP-1 [nTPM]":"44.2","Cell RNA - TIME [nTPM]":"38.6","Cell RNA - U-138 MG [nTPM]":"41.7","Cell RNA - U-2 OS [nTPM]":"45.8","Cell RNA - U-2197 [nTPM]":"63.6","Cell RNA - U-251 MG [nTPM]":"48.7","Cell RNA - U-266\/70 [nTPM]":"23.8","Cell RNA - U-266\/84 [nTPM]":"38.3","Cell RNA - U-698 [nTPM]":"39.0","Cell RNA - U-87 MG [nTPM]":"59.3","Cell RNA - U-937 [nTPM]":"39.8","Cell RNA - WM-115 [nTPM]":"54.9","Blood RNA - basophil [nTPM]":"65.9","Blood RNA - classical monocyte [nTPM]":"42.6","Blood RNA - eosinophil [nTPM]":"60.4","Blood RNA - gdT-cell [nTPM]":"20.6","Blood RNA - intermediate monocyte [nTPM]":"39.6","Blood RNA - MAIT T-cell [nTPM]":"17.1","Blood RNA - memory B-cell [nTPM]":"11.0","Blood RNA - memory CD4 T-cell [nTPM]":"17.5","Blood RNA - memory CD8 T-cell [nTPM]":"19.4","Blood RNA - myeloid DC [nTPM]":"45.6","Blood RNA - naive B-cell [nTPM]":"11.2","Blood RNA - naive CD4 T-cell [nTPM]":"17.1","Blood RNA - naive CD8 T-cell [nTPM]":"14.7","Blood RNA - neutrophil [nTPM]":"53.8","Blood RNA - NK-cell [nTPM]":"25.9","Blood RNA - non-classical monocyte [nTPM]":"30.2","Blood RNA - plasmacytoid DC [nTPM]":"12.5","Blood RNA - T-reg [nTPM]":"19.3","Blood RNA - total PBMC [nTPM]":"36.6","Brain RNA - amygdala [nTPM]":"19.9","Brain RNA - basal ganglia [nTPM]":"20.7","Brain RNA - cerebellum [nTPM]":"14.1","Brain RNA - cerebral cortex [nTPM]":"18.6","Brain RNA - hippocampal formation [nTPM]":"20.7","Brain RNA - hypothalamus [nTPM]":"30.2","Brain RNA - medulla oblongata [nTPM]":"22.2","Brain RNA - midbrain [nTPM]":"24.5","Brain RNA - pons [nTPM]":"20.9","Brain RNA - spinal cord [nTPM]":"16.9","Brain RNA - thalamus [nTPM]":"34.7","Brain RNA - white matter [nTPM]":"15.3","Single Cell Type RNA - Adipocytes [nTPM]":"34.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"39.7","Single Cell Type RNA - Astrocytes [nTPM]":"23.2","Single Cell Type RNA - B-cells [nTPM]":"17.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"29.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"172.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Bipolar cells [nTPM]":"31.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"20.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"54.3","Single Cell Type RNA - Club cells [nTPM]":"201.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"73.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"99.9","Single Cell Type RNA - dendritic cells [nTPM]":"26.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"97.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"65.0","Single Cell Type RNA - Early spermatids [nTPM]":"27.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"62.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"28.0","Single Cell Type RNA - Endothelial cells [nTPM]":"27.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.8","Single Cell Type RNA - Erythroid cells [nTPM]":"11.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"29.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"95.0","Single Cell Type RNA - Fibroblasts [nTPM]":"40.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"67.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"46.6","Single Cell Type RNA - granulocytes [nTPM]":"24.7","Single Cell Type RNA - Granulosa cells [nTPM]":"121.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.2","Single Cell Type RNA - Hepatocytes [nTPM]":"489.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"67.8","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"41.7","Single Cell Type RNA - Ionocytes [nTPM]":"124.1","Single Cell Type RNA - Kupffer cells [nTPM]":"35.2","Single Cell Type RNA - Langerhans cells [nTPM]":"16.1","Single Cell Type RNA - Late spermatids [nTPM]":"9.5","Single Cell Type RNA - Leydig cells [nTPM]":"75.8","Single Cell Type RNA - Macrophages [nTPM]":"47.3","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"20.5","Single Cell Type RNA - Muller glia cells [nTPM]":"25.9","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"27.9","Single Cell Type RNA - Paneth cells [nTPM]":"102.0","Single Cell Type RNA - Peritubular cells [nTPM]":"112.5","Single Cell Type RNA - Plasma cells [nTPM]":"17.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"274.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"31.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"178.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.0","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"32.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"46.9","Single Cell Type RNA - Spermatocytes [nTPM]":"21.3","Single Cell Type RNA - Spermatogonia [nTPM]":"30.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"193.2","Single Cell Type RNA - T-cells [nTPM]":"25.4","Single Cell Type RNA - Theca cells [nTPM]":"647.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"44.5","Single Cell Type RNA - Urothelial cells [nTPM]":"45.9"},{"Gene":"PORCN","Gene synonym":["DHOF","MG61","por","PORC","PPN"],"Ensembl":"ENSG00000102312","Gene description":"Porcupine O-acyltransferase","Uniprot":["Q9H237"],"Chromosome":"X","Position":"48508962-48520814","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"37.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"68.5","Club cells":"44.2","Pancreatic endocrine cells":"36.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HBEC3-KT":"176.9","LHCN-M2":"60.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049215","HPA058413"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA049215":null,"HPA058413":"AB_2683711"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.2","Tissue RNA - adrenal gland [nTPM]":"37.3","Tissue RNA - amygdala [nTPM]":"8.7","Tissue RNA - appendix [nTPM]":"3.3","Tissue RNA - basal ganglia [nTPM]":"8.3","Tissue RNA - bone marrow [nTPM]":"2.9","Tissue RNA - breast [nTPM]":"4.7","Tissue RNA - cerebellum [nTPM]":"7.0","Tissue RNA - cerebral cortex [nTPM]":"10.6","Tissue RNA - cervix [nTPM]":"9.1","Tissue RNA - choroid plexus [nTPM]":"4.5","Tissue RNA - colon [nTPM]":"6.3","Tissue RNA - duodenum [nTPM]":"2.3","Tissue RNA - endometrium 1 [nTPM]":"7.1","Tissue RNA - epididymis [nTPM]":"2.1","Tissue RNA - esophagus [nTPM]":"10.8","Tissue RNA - fallopian tube [nTPM]":"5.8","Tissue RNA - gallbladder [nTPM]":"4.6","Tissue RNA - heart muscle [nTPM]":"11.5","Tissue RNA - hippocampal formation [nTPM]":"11.2","Tissue RNA - hypothalamus [nTPM]":"7.0","Tissue RNA - kidney [nTPM]":"3.7","Tissue RNA - liver [nTPM]":"1.5","Tissue RNA - lung [nTPM]":"4.6","Tissue RNA - lymph node [nTPM]":"3.6","Tissue RNA - medulla oblongata [nTPM]":"7.1","Tissue RNA - midbrain [nTPM]":"6.6","Tissue RNA - ovary [nTPM]":"4.3","Tissue RNA - pancreas [nTPM]":"3.5","Tissue RNA - parathyroid gland [nTPM]":"9.8","Tissue RNA - pituitary gland [nTPM]":"4.7","Tissue RNA - placenta [nTPM]":"2.4","Tissue RNA - pons [nTPM]":"7.2","Tissue RNA - prostate [nTPM]":"4.5","Tissue RNA - rectum [nTPM]":"1.6","Tissue RNA - retina [nTPM]":"7.4","Tissue RNA - salivary gland [nTPM]":"4.9","Tissue RNA - seminal vesicle [nTPM]":"11.6","Tissue RNA - skeletal muscle [nTPM]":"7.6","Tissue RNA - skin 1 [nTPM]":"5.9","Tissue RNA - small intestine [nTPM]":"3.7","Tissue RNA - smooth muscle [nTPM]":"4.6","Tissue RNA - spinal cord [nTPM]":"6.2","Tissue RNA - spleen [nTPM]":"4.5","Tissue RNA - stomach 1 [nTPM]":"5.2","Tissue RNA - testis [nTPM]":"5.1","Tissue RNA - thalamus [nTPM]":"7.7","Tissue RNA - thymus [nTPM]":"2.3","Tissue RNA - thyroid gland [nTPM]":"6.3","Tissue RNA - tongue [nTPM]":"3.5","Tissue RNA - tonsil [nTPM]":"3.3","Tissue RNA - urinary bladder [nTPM]":"6.2","Tissue RNA - vagina [nTPM]":"7.1","Tissue RNA - white matter [nTPM]":"7.8","Cell RNA - A-431 [nTPM]":"13.1","Cell RNA - A549 [nTPM]":"15.6","Cell RNA - AF22 [nTPM]":"3.8","Cell RNA - AN3-CA [nTPM]":"26.6","Cell RNA - ASC diff [nTPM]":"15.9","Cell RNA - ASC TERT1 [nTPM]":"9.4","Cell RNA - BEWO [nTPM]":"1.6","Cell RNA - BJ [nTPM]":"3.7","Cell RNA - BJ hTERT+ [nTPM]":"7.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.9","Cell RNA - CACO-2 [nTPM]":"1.8","Cell RNA - CAPAN-2 [nTPM]":"19.7","Cell RNA - Daudi [nTPM]":"1.1","Cell RNA - EFO-21 [nTPM]":"15.9","Cell RNA - fHDF\/TERT166 [nTPM]":"8.3","Cell RNA - GAMG [nTPM]":"6.5","Cell RNA - HaCaT [nTPM]":"17.3","Cell RNA - HAP1 [nTPM]":"5.5","Cell RNA - HBEC3-KT [nTPM]":"176.9","Cell RNA - HBF TERT88 [nTPM]":"1.8","Cell RNA - HDLM-2 [nTPM]":"8.3","Cell RNA - HEK 293 [nTPM]":"1.8","Cell RNA - HEL [nTPM]":"2.2","Cell RNA - HeLa [nTPM]":"9.0","Cell RNA - Hep G2 [nTPM]":"3.8","Cell RNA - HHSteC [nTPM]":"23.4","Cell RNA - HL-60 [nTPM]":"2.0","Cell RNA - HMC-1 [nTPM]":"22.5","Cell RNA - HSkMC [nTPM]":"12.2","Cell RNA - hTCEpi [nTPM]":"20.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.8","Cell RNA - hTERT-HME1 [nTPM]":"36.0","Cell RNA - hTERT-RPE1 [nTPM]":"13.5","Cell RNA - HUVEC TERT2 [nTPM]":"5.3","Cell RNA - JURKAT [nTPM]":"6.4","Cell RNA - K-562 [nTPM]":"1.0","Cell RNA - Karpas-707 [nTPM]":"12.1","Cell RNA - LHCN-M2 [nTPM]":"60.8","Cell RNA - MCF7 [nTPM]":"3.7","Cell RNA - MOLT-4 [nTPM]":"2.0","Cell RNA - NB-4 [nTPM]":"2.8","Cell RNA - NTERA-2 [nTPM]":"4.9","Cell RNA - OE19 [nTPM]":"4.0","Cell RNA - PC-3 [nTPM]":"10.4","Cell RNA - REH [nTPM]":"4.0","Cell RNA - RH-30 [nTPM]":"4.6","Cell RNA - RPMI-8226 [nTPM]":"20.5","Cell RNA - RPTEC TERT1 [nTPM]":"9.8","Cell RNA - RT4 [nTPM]":"5.1","Cell RNA - SCLC-21H [nTPM]":"4.2","Cell RNA - SH-SY5Y [nTPM]":"6.5","Cell RNA - SiHa [nTPM]":"30.8","Cell RNA - SK-BR-3 [nTPM]":"5.9","Cell RNA - SK-MEL-30 [nTPM]":"5.9","Cell RNA - SuSa [nTPM]":"2.5","Cell RNA - T-47d [nTPM]":"6.7","Cell RNA - THP-1 [nTPM]":"1.0","Cell RNA - TIME [nTPM]":"3.3","Cell RNA - U-138 MG [nTPM]":"15.0","Cell RNA - U-2 OS [nTPM]":"7.8","Cell RNA - U-2197 [nTPM]":"36.4","Cell RNA - U-251 MG [nTPM]":"6.8","Cell RNA - U-266\/70 [nTPM]":"10.4","Cell RNA - U-266\/84 [nTPM]":"6.3","Cell RNA - U-698 [nTPM]":"1.5","Cell RNA - U-87 MG [nTPM]":"43.0","Cell RNA - U-937 [nTPM]":"4.9","Cell RNA - WM-115 [nTPM]":"8.7","Blood RNA - basophil [nTPM]":"16.9","Blood RNA - classical monocyte [nTPM]":"5.5","Blood RNA - eosinophil [nTPM]":"6.8","Blood RNA - gdT-cell [nTPM]":"10.8","Blood RNA - intermediate monocyte [nTPM]":"4.9","Blood RNA - MAIT T-cell [nTPM]":"8.5","Blood RNA - memory B-cell [nTPM]":"3.2","Blood RNA - memory CD4 T-cell [nTPM]":"7.1","Blood RNA - memory CD8 T-cell [nTPM]":"9.0","Blood RNA - myeloid DC [nTPM]":"6.8","Blood RNA - naive B-cell [nTPM]":"3.5","Blood RNA - naive CD4 T-cell [nTPM]":"4.7","Blood RNA - naive CD8 T-cell [nTPM]":"7.1","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"8.4","Blood RNA - non-classical monocyte [nTPM]":"4.3","Blood RNA - plasmacytoid DC [nTPM]":"3.6","Blood RNA - T-reg [nTPM]":"4.9","Blood RNA - total PBMC [nTPM]":"4.7","Brain RNA - amygdala [nTPM]":"8.7","Brain RNA - basal ganglia [nTPM]":"8.3","Brain RNA - cerebellum [nTPM]":"7.0","Brain RNA - cerebral cortex [nTPM]":"10.6","Brain RNA - hippocampal formation [nTPM]":"11.2","Brain RNA - hypothalamus [nTPM]":"7.0","Brain RNA - medulla oblongata [nTPM]":"7.1","Brain RNA - midbrain [nTPM]":"6.6","Brain RNA - pons [nTPM]":"7.2","Brain RNA - spinal cord [nTPM]":"6.2","Brain RNA - thalamus [nTPM]":"7.7","Brain RNA - white matter [nTPM]":"7.8","Single Cell Type RNA - Adipocytes [nTPM]":"5.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.8","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"3.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"68.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"15.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"44.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"7.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.5","Single Cell Type RNA - Endothelial cells [nTPM]":"5.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.3","Single Cell Type RNA - Fibroblasts [nTPM]":"5.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.8","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"3.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.5","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.9","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"2.7","Single Cell Type RNA - Langerhans cells [nTPM]":"4.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"5.6","Single Cell Type RNA - Macrophages [nTPM]":"2.5","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"3.1","Single Cell Type RNA - Muller glia cells [nTPM]":"10.1","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"36.4","Single Cell Type RNA - Paneth cells [nTPM]":"1.8","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"6.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.8","Single Cell Type RNA - Spermatocytes [nTPM]":"2.9","Single Cell Type RNA - Spermatogonia [nTPM]":"4.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.2","Single Cell Type RNA - T-cells [nTPM]":"6.9","Single Cell Type RNA - Theca cells [nTPM]":"7.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.5","Single Cell Type RNA - Urothelial cells [nTPM]":"6.6"},{"Gene":"PPA2","Gene synonym":["FLJ20459"],"Ensembl":"ENSG00000138777","Gene description":"Inorganic pyrophosphatase 2","Uniprot":["Q9H2U2"],"Chromosome":"4","Position":"105369077-105474067","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030888","HPA031671","HPA031672"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"150000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA030888":"AB_2673646","HPA031671":"AB_10603986","HPA031672":"AB_2673988"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.98e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.60e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.26e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.27e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.4","Tissue RNA - adrenal gland [nTPM]":"12.8","Tissue RNA - amygdala [nTPM]":"23.8","Tissue RNA - appendix [nTPM]":"9.0","Tissue RNA - basal ganglia [nTPM]":"24.6","Tissue RNA - bone marrow [nTPM]":"22.0","Tissue RNA - breast [nTPM]":"12.0","Tissue RNA - cerebellum [nTPM]":"24.3","Tissue RNA - cerebral cortex [nTPM]":"53.7","Tissue RNA - cervix [nTPM]":"7.4","Tissue RNA - choroid plexus [nTPM]":"29.5","Tissue RNA - colon [nTPM]":"17.4","Tissue RNA - duodenum [nTPM]":"14.2","Tissue RNA - endometrium 1 [nTPM]":"7.4","Tissue RNA - epididymis [nTPM]":"12.5","Tissue RNA - esophagus [nTPM]":"10.8","Tissue RNA - fallopian tube [nTPM]":"8.4","Tissue RNA - gallbladder [nTPM]":"8.0","Tissue RNA - heart muscle [nTPM]":"27.5","Tissue RNA - hippocampal formation [nTPM]":"23.7","Tissue RNA - hypothalamus [nTPM]":"26.3","Tissue RNA - kidney [nTPM]":"20.7","Tissue RNA - liver [nTPM]":"14.8","Tissue RNA - lung [nTPM]":"7.5","Tissue RNA - lymph node [nTPM]":"8.3","Tissue RNA - medulla oblongata [nTPM]":"24.4","Tissue RNA - midbrain [nTPM]":"24.3","Tissue RNA - ovary [nTPM]":"5.8","Tissue RNA - pancreas [nTPM]":"11.8","Tissue RNA - parathyroid gland [nTPM]":"11.7","Tissue RNA - pituitary gland [nTPM]":"7.7","Tissue RNA - placenta [nTPM]":"7.4","Tissue RNA - pons [nTPM]":"24.5","Tissue RNA - prostate [nTPM]":"13.3","Tissue RNA - rectum [nTPM]":"14.0","Tissue RNA - retina [nTPM]":"13.6","Tissue RNA - salivary gland [nTPM]":"13.8","Tissue RNA - seminal vesicle [nTPM]":"5.7","Tissue RNA - skeletal muscle [nTPM]":"27.6","Tissue RNA - skin 1 [nTPM]":"12.2","Tissue RNA - small intestine [nTPM]":"13.8","Tissue RNA - smooth muscle [nTPM]":"6.8","Tissue RNA - spinal cord [nTPM]":"24.0","Tissue RNA - spleen [nTPM]":"9.9","Tissue RNA - stomach 1 [nTPM]":"12.6","Tissue RNA - testis [nTPM]":"6.3","Tissue RNA - thalamus [nTPM]":"25.4","Tissue RNA - thymus [nTPM]":"7.0","Tissue RNA - thyroid gland [nTPM]":"11.5","Tissue RNA - tongue [nTPM]":"35.5","Tissue RNA - tonsil [nTPM]":"8.7","Tissue RNA - urinary bladder [nTPM]":"8.1","Tissue RNA - vagina [nTPM]":"6.7","Tissue RNA - white matter [nTPM]":"26.6","Cell RNA - A-431 [nTPM]":"20.6","Cell RNA - A549 [nTPM]":"8.5","Cell RNA - AF22 [nTPM]":"18.5","Cell RNA - AN3-CA [nTPM]":"32.3","Cell RNA - ASC diff [nTPM]":"11.3","Cell RNA - ASC TERT1 [nTPM]":"9.1","Cell RNA - BEWO [nTPM]":"12.9","Cell RNA - BJ [nTPM]":"10.2","Cell RNA - BJ hTERT+ [nTPM]":"15.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.9","Cell RNA - CACO-2 [nTPM]":"22.2","Cell RNA - CAPAN-2 [nTPM]":"30.4","Cell RNA - Daudi [nTPM]":"15.6","Cell RNA - EFO-21 [nTPM]":"14.5","Cell RNA - fHDF\/TERT166 [nTPM]":"9.7","Cell RNA - GAMG [nTPM]":"11.3","Cell RNA - HaCaT [nTPM]":"9.5","Cell RNA - HAP1 [nTPM]":"39.2","Cell RNA - HBEC3-KT [nTPM]":"18.7","Cell RNA - HBF TERT88 [nTPM]":"17.0","Cell RNA - HDLM-2 [nTPM]":"23.6","Cell RNA - HEK 293 [nTPM]":"11.8","Cell RNA - HEL [nTPM]":"13.5","Cell RNA - HeLa [nTPM]":"13.7","Cell RNA - Hep G2 [nTPM]":"19.9","Cell RNA - HHSteC [nTPM]":"9.3","Cell RNA - HL-60 [nTPM]":"36.7","Cell RNA - HMC-1 [nTPM]":"13.6","Cell RNA - HSkMC [nTPM]":"9.7","Cell RNA - hTCEpi [nTPM]":"19.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.9","Cell RNA - hTERT-HME1 [nTPM]":"7.9","Cell RNA - hTERT-RPE1 [nTPM]":"15.4","Cell RNA - HUVEC TERT2 [nTPM]":"14.6","Cell RNA - JURKAT [nTPM]":"28.4","Cell RNA - K-562 [nTPM]":"22.3","Cell RNA - Karpas-707 [nTPM]":"22.0","Cell RNA - LHCN-M2 [nTPM]":"12.5","Cell RNA - MCF7 [nTPM]":"26.2","Cell RNA - MOLT-4 [nTPM]":"32.5","Cell RNA - NB-4 [nTPM]":"26.6","Cell RNA - NTERA-2 [nTPM]":"13.9","Cell RNA - OE19 [nTPM]":"42.4","Cell RNA - PC-3 [nTPM]":"28.3","Cell RNA - REH [nTPM]":"28.2","Cell RNA - RH-30 [nTPM]":"10.9","Cell RNA - RPMI-8226 [nTPM]":"17.9","Cell RNA - RPTEC TERT1 [nTPM]":"49.7","Cell RNA - RT4 [nTPM]":"14.7","Cell RNA - SCLC-21H [nTPM]":"17.8","Cell RNA - SH-SY5Y [nTPM]":"10.7","Cell RNA - SiHa [nTPM]":"7.8","Cell RNA - SK-BR-3 [nTPM]":"48.9","Cell RNA - SK-MEL-30 [nTPM]":"19.0","Cell RNA - SuSa [nTPM]":"10.7","Cell RNA - T-47d [nTPM]":"24.8","Cell RNA - THP-1 [nTPM]":"32.1","Cell RNA - TIME [nTPM]":"6.9","Cell RNA - U-138 MG [nTPM]":"9.2","Cell RNA - U-2 OS [nTPM]":"19.2","Cell RNA - U-2197 [nTPM]":"8.9","Cell RNA - U-251 MG [nTPM]":"20.0","Cell RNA - U-266\/70 [nTPM]":"19.0","Cell RNA - U-266\/84 [nTPM]":"27.3","Cell RNA - U-698 [nTPM]":"18.4","Cell RNA - U-87 MG [nTPM]":"17.5","Cell RNA - U-937 [nTPM]":"18.6","Cell RNA - WM-115 [nTPM]":"14.1","Blood RNA - basophil [nTPM]":"27.0","Blood RNA - classical monocyte [nTPM]":"20.9","Blood RNA - eosinophil [nTPM]":"15.4","Blood RNA - gdT-cell [nTPM]":"21.0","Blood RNA - intermediate monocyte [nTPM]":"30.1","Blood RNA - MAIT T-cell [nTPM]":"18.6","Blood RNA - memory B-cell [nTPM]":"28.5","Blood RNA - memory CD4 T-cell [nTPM]":"21.7","Blood RNA - memory CD8 T-cell [nTPM]":"23.7","Blood RNA - myeloid DC [nTPM]":"49.9","Blood RNA - naive B-cell [nTPM]":"22.6","Blood RNA - naive CD4 T-cell [nTPM]":"21.1","Blood RNA - naive CD8 T-cell [nTPM]":"23.9","Blood RNA - neutrophil [nTPM]":"9.5","Blood RNA - NK-cell [nTPM]":"36.4","Blood RNA - non-classical monocyte [nTPM]":"26.4","Blood RNA - plasmacytoid DC [nTPM]":"25.9","Blood RNA - T-reg [nTPM]":"23.4","Blood RNA - total PBMC [nTPM]":"23.5","Brain RNA - amygdala [nTPM]":"23.8","Brain RNA - basal ganglia [nTPM]":"24.6","Brain RNA - cerebellum [nTPM]":"24.3","Brain RNA - cerebral cortex [nTPM]":"53.7","Brain RNA - hippocampal formation [nTPM]":"23.7","Brain RNA - hypothalamus [nTPM]":"26.3","Brain RNA - medulla oblongata [nTPM]":"24.4","Brain RNA - midbrain [nTPM]":"24.3","Brain RNA - pons [nTPM]":"24.5","Brain RNA - spinal cord [nTPM]":"24.0","Brain RNA - thalamus [nTPM]":"25.4","Brain RNA - white matter [nTPM]":"26.6","Single Cell Type RNA - Adipocytes [nTPM]":"26.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"67.3","Single Cell Type RNA - Astrocytes [nTPM]":"86.2","Single Cell Type RNA - B-cells [nTPM]":"37.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"50.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"82.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"205.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"38.1","Single Cell Type RNA - Bipolar cells [nTPM]":"29.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"64.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"40.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"63.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"45.8","Single Cell Type RNA - Club cells [nTPM]":"126.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"119.0","Single Cell Type RNA - dendritic cells [nTPM]":"25.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"73.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"264.1","Single Cell Type RNA - Ductal cells [nTPM]":"114.0","Single Cell Type RNA - Early spermatids [nTPM]":"113.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"42.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"35.3","Single Cell Type RNA - Endothelial cells [nTPM]":"36.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"65.7","Single Cell Type RNA - Erythroid cells [nTPM]":"70.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"138.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"120.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"98.5","Single Cell Type RNA - Fibroblasts [nTPM]":"31.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"37.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"42.3","Single Cell Type RNA - granulocytes [nTPM]":"45.6","Single Cell Type RNA - Granulosa cells [nTPM]":"26.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"24.3","Single Cell Type RNA - Hepatocytes [nTPM]":"64.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"83.5","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"134.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"104.6","Single Cell Type RNA - Ionocytes [nTPM]":"142.4","Single Cell Type RNA - Kupffer cells [nTPM]":"42.9","Single Cell Type RNA - Langerhans cells [nTPM]":"86.1","Single Cell Type RNA - Late spermatids [nTPM]":"126.4","Single Cell Type RNA - Leydig cells [nTPM]":"27.7","Single Cell Type RNA - Macrophages [nTPM]":"47.1","Single Cell Type RNA - Melanocytes [nTPM]":"76.5","Single Cell Type RNA - Microglial cells [nTPM]":"74.9","Single Cell Type RNA - monocytes [nTPM]":"50.5","Single Cell Type RNA - Muller glia cells [nTPM]":"39.2","Single Cell Type RNA - NK-cells [nTPM]":"30.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"169.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"145.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"65.0","Single Cell Type RNA - Paneth cells [nTPM]":"90.4","Single Cell Type RNA - Peritubular cells [nTPM]":"32.4","Single Cell Type RNA - Plasma cells [nTPM]":"41.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"68.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"112.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"285.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"90.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"22.6","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"46.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"43.6","Single Cell Type RNA - Spermatocytes [nTPM]":"50.8","Single Cell Type RNA - Spermatogonia [nTPM]":"10.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"59.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"57.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"84.7","Single Cell Type RNA - T-cells [nTPM]":"34.3","Single Cell Type RNA - Theca cells [nTPM]":"72.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"138.0","Single Cell Type RNA - Urothelial cells [nTPM]":"94.6"},{"Gene":"PPCS","Gene synonym":["FLJ11838"],"Ensembl":"ENSG00000127125","Gene description":"Phosphopantothenoylcysteine synthetase","Uniprot":["Q9HAB8"],"Chromosome":"1","Position":"42456117-42473385","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Ligase"],"Disease involvement":["Cardiomyopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"397.2","Proximal tubular cells":"316.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031361","HPA031363"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"17000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA031361":"AB_10602150","HPA031363":"AB_2673844"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.96e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Tissue RNA - adipose tissue [nTPM]":"51.0","Tissue RNA - adrenal gland [nTPM]":"62.7","Tissue RNA - amygdala [nTPM]":"28.2","Tissue RNA - appendix [nTPM]":"34.6","Tissue RNA - basal ganglia [nTPM]":"29.3","Tissue RNA - bone marrow [nTPM]":"27.1","Tissue RNA - breast [nTPM]":"65.0","Tissue RNA - cerebellum [nTPM]":"29.8","Tissue RNA - cerebral cortex [nTPM]":"34.6","Tissue RNA - cervix [nTPM]":"44.2","Tissue RNA - choroid plexus [nTPM]":"36.8","Tissue RNA - colon [nTPM]":"63.5","Tissue RNA - duodenum [nTPM]":"58.0","Tissue RNA - endometrium 1 [nTPM]":"35.8","Tissue RNA - epididymis [nTPM]":"71.0","Tissue RNA - esophagus [nTPM]":"48.4","Tissue RNA - fallopian tube [nTPM]":"31.7","Tissue RNA - gallbladder [nTPM]":"43.1","Tissue RNA - heart muscle [nTPM]":"42.5","Tissue RNA - hippocampal formation [nTPM]":"28.6","Tissue RNA - hypothalamus [nTPM]":"32.0","Tissue RNA - kidney [nTPM]":"88.1","Tissue RNA - liver [nTPM]":"99.6","Tissue RNA - lung [nTPM]":"39.8","Tissue RNA - lymph node [nTPM]":"43.5","Tissue RNA - medulla oblongata [nTPM]":"30.1","Tissue RNA - midbrain [nTPM]":"28.8","Tissue RNA - ovary [nTPM]":"30.2","Tissue RNA - pancreas [nTPM]":"66.9","Tissue RNA - parathyroid gland [nTPM]":"59.8","Tissue RNA - pituitary gland [nTPM]":"27.8","Tissue RNA - placenta [nTPM]":"38.0","Tissue RNA - pons [nTPM]":"29.1","Tissue RNA - prostate [nTPM]":"52.3","Tissue RNA - rectum [nTPM]":"58.0","Tissue RNA - retina [nTPM]":"22.4","Tissue RNA - salivary gland [nTPM]":"59.3","Tissue RNA - seminal vesicle [nTPM]":"44.2","Tissue RNA - skeletal muscle [nTPM]":"45.9","Tissue RNA - skin 1 [nTPM]":"47.0","Tissue RNA - small intestine [nTPM]":"56.4","Tissue RNA - smooth muscle [nTPM]":"29.0","Tissue RNA - spinal cord [nTPM]":"31.6","Tissue RNA - spleen [nTPM]":"42.2","Tissue RNA - stomach 1 [nTPM]":"64.7","Tissue RNA - testis [nTPM]":"15.0","Tissue RNA - thalamus [nTPM]":"29.9","Tissue RNA - thymus [nTPM]":"27.8","Tissue RNA - thyroid gland [nTPM]":"64.8","Tissue RNA - tongue [nTPM]":"40.4","Tissue RNA - tonsil [nTPM]":"38.2","Tissue RNA - urinary bladder [nTPM]":"43.3","Tissue RNA - vagina [nTPM]":"40.1","Tissue RNA - white matter [nTPM]":"32.9","Cell RNA - A-431 [nTPM]":"83.4","Cell RNA - A549 [nTPM]":"34.3","Cell RNA - AF22 [nTPM]":"17.2","Cell RNA - AN3-CA [nTPM]":"28.8","Cell RNA - ASC diff [nTPM]":"52.3","Cell RNA - ASC TERT1 [nTPM]":"55.0","Cell RNA - BEWO [nTPM]":"72.1","Cell RNA - BJ [nTPM]":"40.7","Cell RNA - BJ hTERT+ [nTPM]":"43.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"49.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"44.2","Cell RNA - CACO-2 [nTPM]":"30.7","Cell RNA - CAPAN-2 [nTPM]":"93.3","Cell RNA - Daudi [nTPM]":"22.6","Cell RNA - EFO-21 [nTPM]":"80.7","Cell RNA - fHDF\/TERT166 [nTPM]":"46.2","Cell RNA - GAMG [nTPM]":"30.3","Cell RNA - HaCaT [nTPM]":"48.8","Cell RNA - HAP1 [nTPM]":"11.5","Cell RNA - HBEC3-KT [nTPM]":"62.5","Cell RNA - HBF TERT88 [nTPM]":"40.3","Cell RNA - HDLM-2 [nTPM]":"66.2","Cell RNA - HEK 293 [nTPM]":"35.1","Cell RNA - HEL [nTPM]":"39.9","Cell RNA - HeLa [nTPM]":"34.7","Cell RNA - Hep G2 [nTPM]":"31.3","Cell RNA - HHSteC [nTPM]":"72.5","Cell RNA - HL-60 [nTPM]":"39.9","Cell RNA - HMC-1 [nTPM]":"69.4","Cell RNA - HSkMC [nTPM]":"48.8","Cell RNA - hTCEpi [nTPM]":"98.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"35.8","Cell RNA - hTERT-HME1 [nTPM]":"62.4","Cell RNA - hTERT-RPE1 [nTPM]":"58.2","Cell RNA - HUVEC TERT2 [nTPM]":"48.3","Cell RNA - JURKAT [nTPM]":"29.9","Cell RNA - K-562 [nTPM]":"16.9","Cell RNA - Karpas-707 [nTPM]":"17.0","Cell RNA - LHCN-M2 [nTPM]":"50.5","Cell RNA - MCF7 [nTPM]":"47.3","Cell RNA - MOLT-4 [nTPM]":"20.4","Cell RNA - NB-4 [nTPM]":"40.1","Cell RNA - NTERA-2 [nTPM]":"22.6","Cell RNA - OE19 [nTPM]":"70.0","Cell RNA - PC-3 [nTPM]":"49.8","Cell RNA - REH [nTPM]":"22.6","Cell RNA - RH-30 [nTPM]":"18.8","Cell RNA - RPMI-8226 [nTPM]":"45.3","Cell RNA - RPTEC TERT1 [nTPM]":"106.2","Cell RNA - RT4 [nTPM]":"70.7","Cell RNA - SCLC-21H [nTPM]":"23.0","Cell RNA - SH-SY5Y [nTPM]":"25.0","Cell RNA - SiHa [nTPM]":"47.9","Cell RNA - SK-BR-3 [nTPM]":"113.2","Cell RNA - SK-MEL-30 [nTPM]":"129.4","Cell RNA - SuSa [nTPM]":"50.2","Cell RNA - T-47d [nTPM]":"56.7","Cell RNA - THP-1 [nTPM]":"167.8","Cell RNA - TIME [nTPM]":"31.1","Cell RNA - U-138 MG [nTPM]":"28.2","Cell RNA - U-2 OS [nTPM]":"41.1","Cell RNA - U-2197 [nTPM]":"42.9","Cell RNA - U-251 MG [nTPM]":"46.5","Cell RNA - U-266\/70 [nTPM]":"58.6","Cell RNA - U-266\/84 [nTPM]":"37.3","Cell RNA - U-698 [nTPM]":"17.5","Cell RNA - U-87 MG [nTPM]":"12.6","Cell RNA - U-937 [nTPM]":"44.4","Cell RNA - WM-115 [nTPM]":"61.0","Blood RNA - basophil [nTPM]":"298.8","Blood RNA - classical monocyte [nTPM]":"231.5","Blood RNA - eosinophil [nTPM]":"325.6","Blood RNA - gdT-cell [nTPM]":"114.5","Blood RNA - intermediate monocyte [nTPM]":"245.4","Blood RNA - MAIT T-cell [nTPM]":"135.2","Blood RNA - memory B-cell [nTPM]":"171.5","Blood RNA - memory CD4 T-cell [nTPM]":"141.1","Blood RNA - memory CD8 T-cell [nTPM]":"128.0","Blood RNA - myeloid DC [nTPM]":"195.9","Blood RNA - naive B-cell [nTPM]":"182.4","Blood RNA - naive CD4 T-cell [nTPM]":"149.5","Blood RNA - naive CD8 T-cell [nTPM]":"132.9","Blood RNA - neutrophil [nTPM]":"159.5","Blood RNA - NK-cell [nTPM]":"185.6","Blood RNA - non-classical monocyte [nTPM]":"237.2","Blood RNA - plasmacytoid DC [nTPM]":"135.8","Blood RNA - T-reg [nTPM]":"160.9","Blood RNA - total PBMC [nTPM]":"262.8","Brain RNA - amygdala [nTPM]":"28.2","Brain RNA - basal ganglia [nTPM]":"29.3","Brain RNA - cerebellum [nTPM]":"29.8","Brain RNA - cerebral cortex [nTPM]":"34.6","Brain RNA - hippocampal formation [nTPM]":"28.6","Brain RNA - hypothalamus [nTPM]":"32.0","Brain RNA - medulla oblongata [nTPM]":"30.1","Brain RNA - midbrain [nTPM]":"28.8","Brain RNA - pons [nTPM]":"29.1","Brain RNA - spinal cord [nTPM]":"31.6","Brain RNA - thalamus [nTPM]":"29.9","Brain RNA - white matter [nTPM]":"32.9","Single Cell Type RNA - Adipocytes [nTPM]":"61.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"57.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"84.1","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"62.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"23.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"42.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"99.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"42.7","Single Cell Type RNA - Bipolar cells [nTPM]":"12.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"91.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"100.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"104.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"84.4","Single Cell Type RNA - Club cells [nTPM]":"90.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"64.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"172.2","Single Cell Type RNA - dendritic cells [nTPM]":"52.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"129.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"397.2","Single Cell Type RNA - Ductal cells [nTPM]":"96.5","Single Cell Type RNA - Early spermatids [nTPM]":"3.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"66.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"43.9","Single Cell Type RNA - Endothelial cells [nTPM]":"48.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"31.3","Single Cell Type RNA - Erythroid cells [nTPM]":"29.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"136.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"131.0","Single Cell Type RNA - Fibroblasts [nTPM]":"52.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"61.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"59.3","Single Cell Type RNA - granulocytes [nTPM]":"57.0","Single Cell Type RNA - Granulosa cells [nTPM]":"52.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"44.6","Single Cell Type RNA - Hepatocytes [nTPM]":"120.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"107.4","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"124.9","Single Cell Type RNA - Ionocytes [nTPM]":"103.7","Single Cell Type RNA - Kupffer cells [nTPM]":"84.4","Single Cell Type RNA - Langerhans cells [nTPM]":"44.3","Single Cell Type RNA - Late spermatids [nTPM]":"4.6","Single Cell Type RNA - Leydig cells [nTPM]":"60.6","Single Cell Type RNA - Macrophages [nTPM]":"76.3","Single Cell Type RNA - Melanocytes [nTPM]":"81.8","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"127.0","Single Cell Type RNA - Muller glia cells [nTPM]":"64.8","Single Cell Type RNA - NK-cells [nTPM]":"79.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"98.5","Single Cell Type RNA - Paneth cells [nTPM]":"125.2","Single Cell Type RNA - Peritubular cells [nTPM]":"63.6","Single Cell Type RNA - Plasma cells [nTPM]":"41.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"51.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"159.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"316.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"63.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"28.0","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"26.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"48.9","Single Cell Type RNA - Spermatocytes [nTPM]":"10.3","Single Cell Type RNA - Spermatogonia [nTPM]":"20.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"66.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"36.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"134.6","Single Cell Type RNA - T-cells [nTPM]":"62.5","Single Cell Type RNA - Theca cells [nTPM]":"103.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"101.2","Single Cell Type RNA - Urothelial cells [nTPM]":"60.1"},{"Gene":"PPIB","Gene synonym":["B","CYP-S1","CYPB","OI9","PPIase","SCYLP"],"Ensembl":"ENSG00000166794","Gene description":"Peptidylprolyl isomerase B","Uniprot":["P23284"],"Chromosome":"15","Position":"64155740-64163134","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Isomerase","Rotamase"],"Disease involvement":["Disease variant","Dwarfism","Osteogenesis imperfecta"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"1473.7","Plasma cells":"2242.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011487","HPA012720"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Endoplasmic reticulum"],"Secretome location":"Secreted to blood","CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"33000000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB011487":"AB_443295","HPA012720":"AB_1847399"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.56e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.02e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Tissue RNA - adipose tissue [nTPM]":"375.5","Tissue RNA - adrenal gland [nTPM]":"377.5","Tissue RNA - amygdala [nTPM]":"230.7","Tissue RNA - appendix [nTPM]":"449.5","Tissue RNA - basal ganglia [nTPM]":"240.3","Tissue RNA - bone marrow [nTPM]":"571.9","Tissue RNA - breast [nTPM]":"361.9","Tissue RNA - cerebellum [nTPM]":"247.9","Tissue RNA - cerebral cortex [nTPM]":"259.2","Tissue RNA - cervix [nTPM]":"611.5","Tissue RNA - choroid plexus [nTPM]":"257.2","Tissue RNA - colon [nTPM]":"401.0","Tissue RNA - duodenum [nTPM]":"365.0","Tissue RNA - endometrium 1 [nTPM]":"383.9","Tissue RNA - epididymis [nTPM]":"899.0","Tissue RNA - esophagus [nTPM]":"298.8","Tissue RNA - fallopian tube [nTPM]":"401.5","Tissue RNA - gallbladder [nTPM]":"379.2","Tissue RNA - heart muscle [nTPM]":"262.0","Tissue RNA - hippocampal formation [nTPM]":"229.7","Tissue RNA - hypothalamus [nTPM]":"256.9","Tissue RNA - kidney [nTPM]":"312.3","Tissue RNA - liver [nTPM]":"737.4","Tissue RNA - lung [nTPM]":"351.1","Tissue RNA - lymph node [nTPM]":"344.5","Tissue RNA - medulla oblongata [nTPM]":"258.1","Tissue RNA - midbrain [nTPM]":"241.4","Tissue RNA - ovary [nTPM]":"386.2","Tissue RNA - pancreas [nTPM]":"644.2","Tissue RNA - parathyroid gland [nTPM]":"345.4","Tissue RNA - pituitary gland [nTPM]":"416.8","Tissue RNA - placenta [nTPM]":"515.2","Tissue RNA - pons [nTPM]":"255.1","Tissue RNA - prostate [nTPM]":"375.7","Tissue RNA - rectum [nTPM]":"411.3","Tissue RNA - retina [nTPM]":"72.3","Tissue RNA - salivary gland [nTPM]":"513.1","Tissue RNA - seminal vesicle [nTPM]":"488.6","Tissue RNA - skeletal muscle [nTPM]":"62.2","Tissue RNA - skin 1 [nTPM]":"205.5","Tissue RNA - small intestine [nTPM]":"334.3","Tissue RNA - smooth muscle [nTPM]":"482.4","Tissue RNA - spinal cord [nTPM]":"247.0","Tissue RNA - spleen [nTPM]":"360.5","Tissue RNA - stomach 1 [nTPM]":"375.0","Tissue RNA - testis [nTPM]":"110.0","Tissue RNA - thalamus [nTPM]":"254.9","Tissue RNA - thymus [nTPM]":"315.6","Tissue RNA - thyroid gland [nTPM]":"672.8","Tissue RNA - tongue [nTPM]":"91.1","Tissue RNA - tonsil [nTPM]":"346.4","Tissue RNA - urinary bladder [nTPM]":"510.9","Tissue RNA - vagina [nTPM]":"295.6","Tissue RNA - white matter [nTPM]":"262.6","Cell RNA - A-431 [nTPM]":"675.6","Cell RNA - A549 [nTPM]":"847.9","Cell RNA - AF22 [nTPM]":"736.7","Cell RNA - AN3-CA [nTPM]":"1666.7","Cell RNA - ASC diff [nTPM]":"2577.0","Cell RNA - ASC TERT1 [nTPM]":"1492.3","Cell RNA - BEWO [nTPM]":"641.9","Cell RNA - BJ [nTPM]":"1570.3","Cell RNA - BJ hTERT+ [nTPM]":"2108.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1248.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1472.3","Cell RNA - CACO-2 [nTPM]":"1242.6","Cell RNA - CAPAN-2 [nTPM]":"1223.1","Cell RNA - Daudi [nTPM]":"653.6","Cell RNA - EFO-21 [nTPM]":"1227.4","Cell RNA - fHDF\/TERT166 [nTPM]":"2513.0","Cell RNA - GAMG [nTPM]":"1235.3","Cell RNA - HaCaT [nTPM]":"1067.7","Cell RNA - HAP1 [nTPM]":"1384.6","Cell RNA - HBEC3-KT [nTPM]":"1080.4","Cell RNA - HBF TERT88 [nTPM]":"641.1","Cell RNA - HDLM-2 [nTPM]":"406.2","Cell RNA - HEK 293 [nTPM]":"491.0","Cell RNA - HEL [nTPM]":"914.5","Cell RNA - HeLa [nTPM]":"915.3","Cell RNA - Hep G2 [nTPM]":"1643.7","Cell RNA - HHSteC [nTPM]":"2682.9","Cell RNA - HL-60 [nTPM]":"915.0","Cell RNA - HMC-1 [nTPM]":"778.1","Cell RNA - HSkMC [nTPM]":"1374.2","Cell RNA - hTCEpi [nTPM]":"1149.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"725.9","Cell RNA - hTERT-HME1 [nTPM]":"1751.3","Cell RNA - hTERT-RPE1 [nTPM]":"1516.7","Cell RNA - HUVEC TERT2 [nTPM]":"1539.2","Cell RNA - JURKAT [nTPM]":"301.1","Cell RNA - K-562 [nTPM]":"645.9","Cell RNA - Karpas-707 [nTPM]":"2174.7","Cell RNA - LHCN-M2 [nTPM]":"966.0","Cell RNA - MCF7 [nTPM]":"1102.6","Cell RNA - MOLT-4 [nTPM]":"280.6","Cell RNA - NB-4 [nTPM]":"1404.9","Cell RNA - NTERA-2 [nTPM]":"625.1","Cell RNA - OE19 [nTPM]":"1879.0","Cell RNA - PC-3 [nTPM]":"529.5","Cell RNA - REH [nTPM]":"520.6","Cell RNA - RH-30 [nTPM]":"784.1","Cell RNA - RPMI-8226 [nTPM]":"3347.9","Cell RNA - RPTEC TERT1 [nTPM]":"1312.7","Cell RNA - RT4 [nTPM]":"1062.6","Cell RNA - SCLC-21H [nTPM]":"410.5","Cell RNA - SH-SY5Y [nTPM]":"647.7","Cell RNA - SiHa [nTPM]":"726.0","Cell RNA - SK-BR-3 [nTPM]":"1224.5","Cell RNA - SK-MEL-30 [nTPM]":"1194.2","Cell RNA - SuSa [nTPM]":"1086.0","Cell RNA - T-47d [nTPM]":"727.6","Cell RNA - THP-1 [nTPM]":"2767.0","Cell RNA - TIME [nTPM]":"927.6","Cell RNA - U-138 MG [nTPM]":"1213.7","Cell RNA - U-2 OS [nTPM]":"975.8","Cell RNA - U-2197 [nTPM]":"679.2","Cell RNA - U-251 MG [nTPM]":"1079.4","Cell RNA - U-266\/70 [nTPM]":"1152.5","Cell RNA - U-266\/84 [nTPM]":"1269.5","Cell RNA - U-698 [nTPM]":"693.4","Cell RNA - U-87 MG [nTPM]":"1129.0","Cell RNA - U-937 [nTPM]":"1478.0","Cell RNA - WM-115 [nTPM]":"1238.2","Blood RNA - basophil [nTPM]":"716.7","Blood RNA - classical monocyte [nTPM]":"712.5","Blood RNA - eosinophil [nTPM]":"491.7","Blood RNA - gdT-cell [nTPM]":"929.6","Blood RNA - intermediate monocyte [nTPM]":"547.3","Blood RNA - MAIT T-cell [nTPM]":"931.8","Blood RNA - memory B-cell [nTPM]":"827.8","Blood RNA - memory CD4 T-cell [nTPM]":"645.0","Blood RNA - memory CD8 T-cell [nTPM]":"762.4","Blood RNA - myeloid DC [nTPM]":"930.9","Blood RNA - naive B-cell [nTPM]":"541.4","Blood RNA - naive CD4 T-cell [nTPM]":"411.3","Blood RNA - naive CD8 T-cell [nTPM]":"558.0","Blood RNA - neutrophil [nTPM]":"347.5","Blood RNA - NK-cell [nTPM]":"668.1","Blood RNA - non-classical monocyte [nTPM]":"369.3","Blood RNA - plasmacytoid DC [nTPM]":"2643.5","Blood RNA - T-reg [nTPM]":"569.3","Blood RNA - total PBMC [nTPM]":"1512.3","Brain RNA - amygdala [nTPM]":"230.7","Brain RNA - basal ganglia [nTPM]":"240.3","Brain RNA - cerebellum [nTPM]":"247.9","Brain RNA - cerebral cortex [nTPM]":"259.2","Brain RNA - hippocampal formation [nTPM]":"229.7","Brain RNA - hypothalamus [nTPM]":"256.9","Brain RNA - medulla oblongata [nTPM]":"258.1","Brain RNA - midbrain [nTPM]":"241.4","Brain RNA - pons [nTPM]":"255.1","Brain RNA - spinal cord [nTPM]":"247.0","Brain RNA - thalamus [nTPM]":"254.9","Brain RNA - white matter [nTPM]":"262.6","Single Cell Type RNA - Adipocytes [nTPM]":"389.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"125.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"209.0","Single Cell Type RNA - Astrocytes [nTPM]":"16.6","Single Cell Type RNA - B-cells [nTPM]":"375.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"160.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"426.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"614.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"234.5","Single Cell Type RNA - Bipolar cells [nTPM]":"34.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"264.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"303.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"270.2","Single Cell Type RNA - Club cells [nTPM]":"328.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"272.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"625.9","Single Cell Type RNA - dendritic cells [nTPM]":"560.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"271.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"90.1","Single Cell Type RNA - Ductal cells [nTPM]":"665.1","Single Cell Type RNA - Early spermatids [nTPM]":"19.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"295.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"910.1","Single Cell Type RNA - Endothelial cells [nTPM]":"285.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"297.0","Single Cell Type RNA - Erythroid cells [nTPM]":"172.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"566.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1473.7","Single Cell Type RNA - Fibroblasts [nTPM]":"627.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"441.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"494.2","Single Cell Type RNA - granulocytes [nTPM]":"181.2","Single Cell Type RNA - Granulosa cells [nTPM]":"540.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"322.7","Single Cell Type RNA - Hepatocytes [nTPM]":"473.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"630.1","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"603.9","Single Cell Type RNA - Ionocytes [nTPM]":"205.4","Single Cell Type RNA - Kupffer cells [nTPM]":"216.9","Single Cell Type RNA - Langerhans cells [nTPM]":"333.4","Single Cell Type RNA - Late spermatids [nTPM]":"29.5","Single Cell Type RNA - Leydig cells [nTPM]":"456.3","Single Cell Type RNA - Macrophages [nTPM]":"316.6","Single Cell Type RNA - Melanocytes [nTPM]":"281.1","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"299.1","Single Cell Type RNA - Muller glia cells [nTPM]":"149.1","Single Cell Type RNA - NK-cells [nTPM]":"368.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"35.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"37.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"435.1","Single Cell Type RNA - Paneth cells [nTPM]":"338.9","Single Cell Type RNA - Peritubular cells [nTPM]":"393.1","Single Cell Type RNA - Plasma cells [nTPM]":"2242.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"569.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"338.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"287.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"168.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"43.7","Single Cell Type RNA - Sertoli cells [nTPM]":"230.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"204.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"445.6","Single Cell Type RNA - Spermatocytes [nTPM]":"38.4","Single Cell Type RNA - Spermatogonia [nTPM]":"76.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"337.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"144.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1118.9","Single Cell Type RNA - T-cells [nTPM]":"352.3","Single Cell Type RNA - Theca cells [nTPM]":"674.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"477.2","Single Cell Type RNA - Urothelial cells [nTPM]":"422.3"},{"Gene":"PPIP5K2","Gene synonym":["CFAP160","DFNB100","HISPPD1","KIAA0433","VIP2"],"Ensembl":"ENSG00000145725","Gene description":"Diphosphoinositol pentakisphosphate kinase 2","Uniprot":["O43314"],"Chromosome":"5","Position":"103120149-103212799","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Hearing"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"160.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037895","HPA038442"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA037895":"AB_2675724","HPA038442":"AB_10673173"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.12e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.7","Tissue RNA - adrenal gland [nTPM]":"19.1","Tissue RNA - amygdala [nTPM]":"6.8","Tissue RNA - appendix [nTPM]":"22.0","Tissue RNA - basal ganglia [nTPM]":"7.9","Tissue RNA - bone marrow [nTPM]":"51.6","Tissue RNA - breast [nTPM]":"25.1","Tissue RNA - cerebellum [nTPM]":"18.9","Tissue RNA - cerebral cortex [nTPM]":"13.9","Tissue RNA - cervix [nTPM]":"22.2","Tissue RNA - choroid plexus [nTPM]":"5.8","Tissue RNA - colon [nTPM]":"28.1","Tissue RNA - duodenum [nTPM]":"18.3","Tissue RNA - endometrium 1 [nTPM]":"20.6","Tissue RNA - epididymis [nTPM]":"21.2","Tissue RNA - esophagus [nTPM]":"17.1","Tissue RNA - fallopian tube [nTPM]":"14.5","Tissue RNA - gallbladder [nTPM]":"20.4","Tissue RNA - heart muscle [nTPM]":"19.5","Tissue RNA - hippocampal formation [nTPM]":"6.7","Tissue RNA - hypothalamus [nTPM]":"8.9","Tissue RNA - kidney [nTPM]":"20.3","Tissue RNA - liver [nTPM]":"29.2","Tissue RNA - lung [nTPM]":"16.2","Tissue RNA - lymph node [nTPM]":"25.5","Tissue RNA - medulla oblongata [nTPM]":"15.4","Tissue RNA - midbrain [nTPM]":"11.9","Tissue RNA - ovary [nTPM]":"26.1","Tissue RNA - pancreas [nTPM]":"26.7","Tissue RNA - parathyroid gland [nTPM]":"23.0","Tissue RNA - pituitary gland [nTPM]":"18.1","Tissue RNA - placenta [nTPM]":"16.7","Tissue RNA - pons [nTPM]":"15.1","Tissue RNA - prostate [nTPM]":"16.3","Tissue RNA - rectum [nTPM]":"25.5","Tissue RNA - retina [nTPM]":"19.2","Tissue RNA - salivary gland [nTPM]":"17.1","Tissue RNA - seminal vesicle [nTPM]":"15.4","Tissue RNA - skeletal muscle [nTPM]":"4.2","Tissue RNA - skin 1 [nTPM]":"17.2","Tissue RNA - small intestine [nTPM]":"16.5","Tissue RNA - smooth muscle [nTPM]":"18.4","Tissue RNA - spinal cord [nTPM]":"6.1","Tissue RNA - spleen [nTPM]":"23.9","Tissue RNA - stomach 1 [nTPM]":"22.5","Tissue RNA - testis [nTPM]":"15.1","Tissue RNA - thalamus [nTPM]":"7.3","Tissue RNA - thymus [nTPM]":"27.9","Tissue RNA - thyroid gland [nTPM]":"23.3","Tissue RNA - tongue [nTPM]":"7.7","Tissue RNA - tonsil [nTPM]":"24.5","Tissue RNA - urinary bladder [nTPM]":"17.8","Tissue RNA - vagina [nTPM]":"13.9","Tissue RNA - white matter [nTPM]":"10.7","Cell RNA - A-431 [nTPM]":"27.4","Cell RNA - A549 [nTPM]":"25.3","Cell RNA - AF22 [nTPM]":"50.8","Cell RNA - AN3-CA [nTPM]":"65.2","Cell RNA - ASC diff [nTPM]":"40.8","Cell RNA - ASC TERT1 [nTPM]":"53.4","Cell RNA - BEWO [nTPM]":"47.8","Cell RNA - BJ [nTPM]":"63.5","Cell RNA - BJ hTERT+ [nTPM]":"39.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"34.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"47.6","Cell RNA - CACO-2 [nTPM]":"20.9","Cell RNA - CAPAN-2 [nTPM]":"48.3","Cell RNA - Daudi [nTPM]":"67.6","Cell RNA - EFO-21 [nTPM]":"56.2","Cell RNA - fHDF\/TERT166 [nTPM]":"60.9","Cell RNA - GAMG [nTPM]":"52.7","Cell RNA - HaCaT [nTPM]":"16.5","Cell RNA - HAP1 [nTPM]":"43.9","Cell RNA - HBEC3-KT [nTPM]":"33.2","Cell RNA - HBF TERT88 [nTPM]":"57.5","Cell RNA - HDLM-2 [nTPM]":"53.7","Cell RNA - HEK 293 [nTPM]":"23.5","Cell RNA - HEL [nTPM]":"84.7","Cell RNA - HeLa [nTPM]":"44.3","Cell RNA - Hep G2 [nTPM]":"33.4","Cell RNA - HHSteC [nTPM]":"29.0","Cell RNA - HL-60 [nTPM]":"72.1","Cell RNA - HMC-1 [nTPM]":"70.4","Cell RNA - HSkMC [nTPM]":"34.5","Cell RNA - hTCEpi [nTPM]":"23.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"52.0","Cell RNA - hTERT-HME1 [nTPM]":"46.1","Cell RNA - hTERT-RPE1 [nTPM]":"31.2","Cell RNA - HUVEC TERT2 [nTPM]":"40.0","Cell RNA - JURKAT [nTPM]":"42.5","Cell RNA - K-562 [nTPM]":"84.9","Cell RNA - Karpas-707 [nTPM]":"57.0","Cell RNA - LHCN-M2 [nTPM]":"53.1","Cell RNA - MCF7 [nTPM]":"21.3","Cell RNA - MOLT-4 [nTPM]":"60.9","Cell RNA - NB-4 [nTPM]":"44.6","Cell RNA - NTERA-2 [nTPM]":"55.4","Cell RNA - OE19 [nTPM]":"12.7","Cell RNA - PC-3 [nTPM]":"64.4","Cell RNA - REH [nTPM]":"58.6","Cell RNA - RH-30 [nTPM]":"46.7","Cell RNA - RPMI-8226 [nTPM]":"89.3","Cell RNA - RPTEC TERT1 [nTPM]":"36.8","Cell RNA - RT4 [nTPM]":"31.5","Cell RNA - SCLC-21H [nTPM]":"29.6","Cell RNA - SH-SY5Y [nTPM]":"40.1","Cell RNA - SiHa [nTPM]":"43.5","Cell RNA - SK-BR-3 [nTPM]":"39.9","Cell RNA - SK-MEL-30 [nTPM]":"40.7","Cell RNA - SuSa [nTPM]":"34.0","Cell RNA - T-47d [nTPM]":"33.5","Cell RNA - THP-1 [nTPM]":"48.9","Cell RNA - TIME [nTPM]":"42.7","Cell RNA - U-138 MG [nTPM]":"55.8","Cell RNA - U-2 OS [nTPM]":"25.7","Cell RNA - U-2197 [nTPM]":"56.0","Cell RNA - U-251 MG [nTPM]":"45.1","Cell RNA - U-266\/70 [nTPM]":"38.1","Cell RNA - U-266\/84 [nTPM]":"87.3","Cell RNA - U-698 [nTPM]":"91.3","Cell RNA - U-87 MG [nTPM]":"31.5","Cell RNA - U-937 [nTPM]":"116.0","Cell RNA - WM-115 [nTPM]":"51.2","Blood RNA - basophil [nTPM]":"41.7","Blood RNA - classical monocyte [nTPM]":"21.5","Blood RNA - eosinophil [nTPM]":"39.6","Blood RNA - gdT-cell [nTPM]":"13.0","Blood RNA - intermediate monocyte [nTPM]":"22.9","Blood RNA - MAIT T-cell [nTPM]":"15.8","Blood RNA - memory B-cell [nTPM]":"19.5","Blood RNA - memory CD4 T-cell [nTPM]":"12.6","Blood RNA - memory CD8 T-cell [nTPM]":"14.2","Blood RNA - myeloid DC [nTPM]":"25.6","Blood RNA - naive B-cell [nTPM]":"16.1","Blood RNA - naive CD4 T-cell [nTPM]":"16.1","Blood RNA - naive CD8 T-cell [nTPM]":"17.0","Blood RNA - neutrophil [nTPM]":"19.7","Blood RNA - NK-cell [nTPM]":"17.8","Blood RNA - non-classical monocyte [nTPM]":"32.4","Blood RNA - plasmacytoid DC [nTPM]":"15.5","Blood RNA - T-reg [nTPM]":"12.3","Blood RNA - total PBMC [nTPM]":"11.1","Brain RNA - amygdala [nTPM]":"6.8","Brain RNA - basal ganglia [nTPM]":"7.9","Brain RNA - cerebellum [nTPM]":"18.9","Brain RNA - cerebral cortex [nTPM]":"13.9","Brain RNA - hippocampal formation [nTPM]":"6.7","Brain RNA - hypothalamus [nTPM]":"8.9","Brain RNA - medulla oblongata [nTPM]":"15.4","Brain RNA - midbrain [nTPM]":"11.9","Brain RNA - pons [nTPM]":"15.1","Brain RNA - spinal cord [nTPM]":"6.1","Brain RNA - thalamus [nTPM]":"7.3","Brain RNA - white matter [nTPM]":"10.7","Single Cell Type RNA - Adipocytes [nTPM]":"35.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.1","Single Cell Type RNA - Astrocytes [nTPM]":"49.3","Single Cell Type RNA - B-cells [nTPM]":"39.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.9","Single Cell Type RNA - Bipolar cells [nTPM]":"38.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"26.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"48.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"29.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.7","Single Cell Type RNA - dendritic cells [nTPM]":"35.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"29.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.6","Single Cell Type RNA - Early spermatids [nTPM]":"5.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"44.7","Single Cell Type RNA - Endothelial cells [nTPM]":"28.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.3","Single Cell Type RNA - Erythroid cells [nTPM]":"70.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"88.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.2","Single Cell Type RNA - Fibroblasts [nTPM]":"33.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"33.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"30.6","Single Cell Type RNA - granulocytes [nTPM]":"43.6","Single Cell Type RNA - Granulosa cells [nTPM]":"49.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"20.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.6","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"160.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.2","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"39.5","Single Cell Type RNA - Langerhans cells [nTPM]":"22.4","Single Cell Type RNA - Late spermatids [nTPM]":"6.7","Single Cell Type RNA - Leydig cells [nTPM]":"29.5","Single Cell Type RNA - Macrophages [nTPM]":"43.3","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"49.6","Single Cell Type RNA - monocytes [nTPM]":"47.5","Single Cell Type RNA - Muller glia cells [nTPM]":"14.5","Single Cell Type RNA - NK-cells [nTPM]":"27.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"62.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"67.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.9","Single Cell Type RNA - Paneth cells [nTPM]":"19.1","Single Cell Type RNA - Peritubular cells [nTPM]":"23.7","Single Cell Type RNA - Plasma cells [nTPM]":"56.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"25.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"25.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"28.1","Single Cell Type RNA - Spermatocytes [nTPM]":"39.7","Single Cell Type RNA - Spermatogonia [nTPM]":"21.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"31.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"26.0","Single Cell Type RNA - T-cells [nTPM]":"31.6","Single Cell Type RNA - Theca cells [nTPM]":"38.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"30.1","Single Cell Type RNA - Urothelial cells [nTPM]":"12.6"},{"Gene":"PPM1D","Gene synonym":["PP2C-DELTA","Wip1"],"Ensembl":"ENSG00000170836","Gene description":"Protein phosphatase, Mg2+\/Mn2+ dependent 1D","Uniprot":["O15297"],"Chromosome":"17","Position":"60600183-60666280","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":["Autism spectrum disorder","Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"68.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"34.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022277","HPA061848"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA022277":"AB_1858839","HPA061848":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.52e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.27e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Tissue RNA - adipose tissue [nTPM]":"4.4","Tissue RNA - adrenal gland [nTPM]":"2.4","Tissue RNA - amygdala [nTPM]":"2.7","Tissue RNA - appendix [nTPM]":"2.2","Tissue RNA - basal ganglia [nTPM]":"5.2","Tissue RNA - bone marrow [nTPM]":"5.9","Tissue RNA - breast [nTPM]":"3.9","Tissue RNA - cerebellum [nTPM]":"14.8","Tissue RNA - cerebral cortex [nTPM]":"4.6","Tissue RNA - cervix [nTPM]":"4.5","Tissue RNA - choroid plexus [nTPM]":"5.0","Tissue RNA - colon [nTPM]":"3.1","Tissue RNA - duodenum [nTPM]":"2.9","Tissue RNA - endometrium 1 [nTPM]":"4.3","Tissue RNA - epididymis [nTPM]":"2.9","Tissue RNA - esophagus [nTPM]":"3.5","Tissue RNA - fallopian tube [nTPM]":"3.7","Tissue RNA - gallbladder [nTPM]":"3.1","Tissue RNA - heart muscle [nTPM]":"2.9","Tissue RNA - hippocampal formation [nTPM]":"3.3","Tissue RNA - hypothalamus [nTPM]":"3.4","Tissue RNA - kidney [nTPM]":"2.8","Tissue RNA - liver [nTPM]":"2.8","Tissue RNA - lung [nTPM]":"3.6","Tissue RNA - lymph node [nTPM]":"2.7","Tissue RNA - medulla oblongata [nTPM]":"4.0","Tissue RNA - midbrain [nTPM]":"3.5","Tissue RNA - ovary [nTPM]":"6.3","Tissue RNA - pancreas [nTPM]":"3.3","Tissue RNA - parathyroid gland [nTPM]":"2.3","Tissue RNA - pituitary gland [nTPM]":"2.4","Tissue RNA - placenta [nTPM]":"5.9","Tissue RNA - pons [nTPM]":"4.7","Tissue RNA - prostate [nTPM]":"3.1","Tissue RNA - rectum [nTPM]":"3.5","Tissue RNA - retina [nTPM]":"6.4","Tissue RNA - salivary gland [nTPM]":"3.1","Tissue RNA - seminal vesicle [nTPM]":"2.2","Tissue RNA - skeletal muscle [nTPM]":"4.0","Tissue RNA - skin 1 [nTPM]":"2.9","Tissue RNA - small intestine [nTPM]":"2.7","Tissue RNA - smooth muscle [nTPM]":"3.0","Tissue RNA - spinal cord [nTPM]":"3.4","Tissue RNA - spleen [nTPM]":"3.8","Tissue RNA - stomach 1 [nTPM]":"2.7","Tissue RNA - testis [nTPM]":"5.5","Tissue RNA - thalamus [nTPM]":"3.7","Tissue RNA - thymus [nTPM]":"4.4","Tissue RNA - thyroid gland [nTPM]":"2.9","Tissue RNA - tongue [nTPM]":"3.1","Tissue RNA - tonsil [nTPM]":"2.3","Tissue RNA - urinary bladder [nTPM]":"2.8","Tissue RNA - vagina [nTPM]":"4.0","Tissue RNA - white matter [nTPM]":"9.1","Cell RNA - A-431 [nTPM]":"3.8","Cell RNA - A549 [nTPM]":"6.9","Cell RNA - AF22 [nTPM]":"7.5","Cell RNA - AN3-CA [nTPM]":"6.4","Cell RNA - ASC diff [nTPM]":"5.0","Cell RNA - ASC TERT1 [nTPM]":"3.1","Cell RNA - BEWO [nTPM]":"10.7","Cell RNA - BJ [nTPM]":"5.8","Cell RNA - BJ hTERT+ [nTPM]":"3.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.9","Cell RNA - CACO-2 [nTPM]":"7.1","Cell RNA - CAPAN-2 [nTPM]":"2.0","Cell RNA - Daudi [nTPM]":"9.9","Cell RNA - EFO-21 [nTPM]":"4.5","Cell RNA - fHDF\/TERT166 [nTPM]":"3.7","Cell RNA - GAMG [nTPM]":"1.3","Cell RNA - HaCaT [nTPM]":"3.4","Cell RNA - HAP1 [nTPM]":"4.9","Cell RNA - HBEC3-KT [nTPM]":"2.2","Cell RNA - HBF TERT88 [nTPM]":"4.6","Cell RNA - HDLM-2 [nTPM]":"1.9","Cell RNA - HEK 293 [nTPM]":"11.1","Cell RNA - HEL [nTPM]":"7.4","Cell RNA - HeLa [nTPM]":"6.7","Cell RNA - Hep G2 [nTPM]":"8.1","Cell RNA - HHSteC [nTPM]":"4.2","Cell RNA - HL-60 [nTPM]":"2.9","Cell RNA - HMC-1 [nTPM]":"5.3","Cell RNA - HSkMC [nTPM]":"2.7","Cell RNA - hTCEpi [nTPM]":"3.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.1","Cell RNA - hTERT-HME1 [nTPM]":"3.0","Cell RNA - hTERT-RPE1 [nTPM]":"2.8","Cell RNA - HUVEC TERT2 [nTPM]":"7.9","Cell RNA - JURKAT [nTPM]":"4.1","Cell RNA - K-562 [nTPM]":"5.4","Cell RNA - Karpas-707 [nTPM]":"4.0","Cell RNA - LHCN-M2 [nTPM]":"3.7","Cell RNA - MCF7 [nTPM]":"34.4","Cell RNA - MOLT-4 [nTPM]":"8.1","Cell RNA - NB-4 [nTPM]":"4.4","Cell RNA - NTERA-2 [nTPM]":"3.5","Cell RNA - OE19 [nTPM]":"3.4","Cell RNA - PC-3 [nTPM]":"5.2","Cell RNA - REH [nTPM]":"9.5","Cell RNA - RH-30 [nTPM]":"9.6","Cell RNA - RPMI-8226 [nTPM]":"6.6","Cell RNA - RPTEC TERT1 [nTPM]":"3.1","Cell RNA - RT4 [nTPM]":"4.2","Cell RNA - SCLC-21H [nTPM]":"10.5","Cell RNA - SH-SY5Y [nTPM]":"7.4","Cell RNA - SiHa [nTPM]":"7.1","Cell RNA - SK-BR-3 [nTPM]":"2.4","Cell RNA - SK-MEL-30 [nTPM]":"1.6","Cell RNA - SuSa [nTPM]":"8.0","Cell RNA - T-47d [nTPM]":"2.8","Cell RNA - THP-1 [nTPM]":"3.9","Cell RNA - TIME [nTPM]":"5.7","Cell RNA - U-138 MG [nTPM]":"4.7","Cell RNA - U-2 OS [nTPM]":"12.5","Cell RNA - U-2197 [nTPM]":"3.5","Cell RNA - U-251 MG [nTPM]":"3.3","Cell RNA - U-266\/70 [nTPM]":"6.7","Cell RNA - U-266\/84 [nTPM]":"7.7","Cell RNA - U-698 [nTPM]":"7.3","Cell RNA - U-87 MG [nTPM]":"1.7","Cell RNA - U-937 [nTPM]":"2.9","Cell RNA - WM-115 [nTPM]":"3.8","Blood RNA - basophil [nTPM]":"9.9","Blood RNA - classical monocyte [nTPM]":"16.1","Blood RNA - eosinophil [nTPM]":"18.0","Blood RNA - gdT-cell [nTPM]":"7.6","Blood RNA - intermediate monocyte [nTPM]":"12.5","Blood RNA - MAIT T-cell [nTPM]":"6.8","Blood RNA - memory B-cell [nTPM]":"8.9","Blood RNA - memory CD4 T-cell [nTPM]":"6.3","Blood RNA - memory CD8 T-cell [nTPM]":"7.0","Blood RNA - myeloid DC [nTPM]":"16.0","Blood RNA - naive B-cell [nTPM]":"6.2","Blood RNA - naive CD4 T-cell [nTPM]":"6.8","Blood RNA - naive CD8 T-cell [nTPM]":"7.0","Blood RNA - neutrophil [nTPM]":"24.7","Blood RNA - NK-cell [nTPM]":"8.6","Blood RNA - non-classical monocyte [nTPM]":"8.1","Blood RNA - plasmacytoid DC [nTPM]":"7.0","Blood RNA - T-reg [nTPM]":"10.6","Blood RNA - total PBMC [nTPM]":"9.8","Brain RNA - amygdala [nTPM]":"2.7","Brain RNA - basal ganglia [nTPM]":"5.2","Brain RNA - cerebellum [nTPM]":"14.8","Brain RNA - cerebral cortex [nTPM]":"4.6","Brain RNA - hippocampal formation [nTPM]":"3.3","Brain RNA - hypothalamus [nTPM]":"3.4","Brain RNA - medulla oblongata [nTPM]":"4.0","Brain RNA - midbrain [nTPM]":"3.5","Brain RNA - pons [nTPM]":"4.7","Brain RNA - spinal cord [nTPM]":"3.4","Brain RNA - thalamus [nTPM]":"3.7","Brain RNA - white matter [nTPM]":"9.1","Single Cell Type RNA - Adipocytes [nTPM]":"40.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.7","Single Cell Type RNA - Astrocytes [nTPM]":"15.0","Single Cell Type RNA - B-cells [nTPM]":"23.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"21.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"52.3","Single Cell Type RNA - Bipolar cells [nTPM]":"13.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"4.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"17.6","Single Cell Type RNA - dendritic cells [nTPM]":"19.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.6","Single Cell Type RNA - Early spermatids [nTPM]":"68.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.5","Single Cell Type RNA - Endothelial cells [nTPM]":"25.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.4","Single Cell Type RNA - Erythroid cells [nTPM]":"14.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.4","Single Cell Type RNA - Fibroblasts [nTPM]":"14.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.6","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"7.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.6","Single Cell Type RNA - Hepatocytes [nTPM]":"4.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.8","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.4","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"21.4","Single Cell Type RNA - Langerhans cells [nTPM]":"19.2","Single Cell Type RNA - Late spermatids [nTPM]":"12.8","Single Cell Type RNA - Leydig cells [nTPM]":"13.7","Single Cell Type RNA - Macrophages [nTPM]":"16.1","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"28.1","Single Cell Type RNA - monocytes [nTPM]":"12.3","Single Cell Type RNA - Muller glia cells [nTPM]":"7.0","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"38.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.4","Single Cell Type RNA - Paneth cells [nTPM]":"10.2","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"24.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.0","Single Cell Type RNA - Spermatocytes [nTPM]":"43.8","Single Cell Type RNA - Spermatogonia [nTPM]":"15.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"34.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"38.6","Single Cell Type RNA - T-cells [nTPM]":"18.1","Single Cell Type RNA - Theca cells [nTPM]":"6.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.5","Single Cell Type RNA - Urothelial cells [nTPM]":"7.7"},{"Gene":"PPM1K","Gene synonym":["BDP","DKFZp761G058","hPTMP","PP2Ckappa","PP2Cm"],"Ensembl":"ENSG00000163644","Gene description":"Protein phosphatase, Mg2+\/Mn2+ dependent 1K","Uniprot":["Q8N3J5"],"Chromosome":"4","Position":"88257620-88284769","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"92.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"512.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"58.0","Karpas-707":"48.6","U-698":"48.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020066","HPA020862","HPA023891"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA020066":"AB_1855628","HPA020862":"AB_1855629","HPA023891":"AB_1855630"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.42e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.25e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.3","Tissue RNA - adrenal gland [nTPM]":"8.5","Tissue RNA - amygdala [nTPM]":"23.3","Tissue RNA - appendix [nTPM]":"14.9","Tissue RNA - basal ganglia [nTPM]":"26.3","Tissue RNA - bone marrow [nTPM]":"9.9","Tissue RNA - breast [nTPM]":"14.5","Tissue RNA - cerebellum [nTPM]":"22.5","Tissue RNA - cerebral cortex [nTPM]":"31.2","Tissue RNA - cervix [nTPM]":"19.4","Tissue RNA - choroid plexus [nTPM]":"22.0","Tissue RNA - colon [nTPM]":"5.9","Tissue RNA - duodenum [nTPM]":"4.4","Tissue RNA - endometrium 1 [nTPM]":"32.7","Tissue RNA - epididymis [nTPM]":"7.6","Tissue RNA - esophagus [nTPM]":"11.2","Tissue RNA - fallopian tube [nTPM]":"21.5","Tissue RNA - gallbladder [nTPM]":"8.9","Tissue RNA - heart muscle [nTPM]":"92.5","Tissue RNA - hippocampal formation [nTPM]":"26.5","Tissue RNA - hypothalamus [nTPM]":"23.9","Tissue RNA - kidney [nTPM]":"17.8","Tissue RNA - liver [nTPM]":"7.6","Tissue RNA - lung [nTPM]":"9.7","Tissue RNA - lymph node [nTPM]":"25.6","Tissue RNA - medulla oblongata [nTPM]":"19.9","Tissue RNA - midbrain [nTPM]":"22.3","Tissue RNA - ovary [nTPM]":"32.5","Tissue RNA - pancreas [nTPM]":"11.1","Tissue RNA - parathyroid gland [nTPM]":"12.5","Tissue RNA - pituitary gland [nTPM]":"9.9","Tissue RNA - placenta [nTPM]":"9.7","Tissue RNA - pons [nTPM]":"22.9","Tissue RNA - prostate [nTPM]":"16.2","Tissue RNA - rectum [nTPM]":"6.0","Tissue RNA - retina [nTPM]":"14.2","Tissue RNA - salivary gland [nTPM]":"11.8","Tissue RNA - seminal vesicle [nTPM]":"7.1","Tissue RNA - skeletal muscle [nTPM]":"14.2","Tissue RNA - skin 1 [nTPM]":"2.6","Tissue RNA - small intestine [nTPM]":"10.4","Tissue RNA - smooth muscle [nTPM]":"26.6","Tissue RNA - spinal cord [nTPM]":"22.1","Tissue RNA - spleen [nTPM]":"18.9","Tissue RNA - stomach 1 [nTPM]":"8.0","Tissue RNA - testis [nTPM]":"19.9","Tissue RNA - thalamus [nTPM]":"27.7","Tissue RNA - thymus [nTPM]":"15.2","Tissue RNA - thyroid gland [nTPM]":"7.9","Tissue RNA - tongue [nTPM]":"11.5","Tissue RNA - tonsil [nTPM]":"25.8","Tissue RNA - urinary bladder [nTPM]":"8.9","Tissue RNA - vagina [nTPM]":"11.7","Tissue RNA - white matter [nTPM]":"33.2","Cell RNA - A-431 [nTPM]":"4.6","Cell RNA - A549 [nTPM]":"1.5","Cell RNA - AF22 [nTPM]":"5.7","Cell RNA - AN3-CA [nTPM]":"10.1","Cell RNA - ASC diff [nTPM]":"8.3","Cell RNA - ASC TERT1 [nTPM]":"10.9","Cell RNA - BEWO [nTPM]":"2.3","Cell RNA - BJ [nTPM]":"7.2","Cell RNA - BJ hTERT+ [nTPM]":"13.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"27.4","Cell RNA - CACO-2 [nTPM]":"11.6","Cell RNA - CAPAN-2 [nTPM]":"1.1","Cell RNA - Daudi [nTPM]":"58.0","Cell RNA - EFO-21 [nTPM]":"7.7","Cell RNA - fHDF\/TERT166 [nTPM]":"4.6","Cell RNA - GAMG [nTPM]":"11.5","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"17.0","Cell RNA - HBEC3-KT [nTPM]":"5.4","Cell RNA - HBF TERT88 [nTPM]":"9.1","Cell RNA - HDLM-2 [nTPM]":"44.9","Cell RNA - HEK 293 [nTPM]":"7.1","Cell RNA - HEL [nTPM]":"10.8","Cell RNA - HeLa [nTPM]":"5.0","Cell RNA - Hep G2 [nTPM]":"10.8","Cell RNA - HHSteC [nTPM]":"6.6","Cell RNA - HL-60 [nTPM]":"14.6","Cell RNA - HMC-1 [nTPM]":"5.3","Cell RNA - HSkMC [nTPM]":"7.2","Cell RNA - hTCEpi [nTPM]":"2.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.5","Cell RNA - hTERT-HME1 [nTPM]":"12.5","Cell RNA - hTERT-RPE1 [nTPM]":"4.9","Cell RNA - HUVEC TERT2 [nTPM]":"4.2","Cell RNA - JURKAT [nTPM]":"25.4","Cell RNA - K-562 [nTPM]":"15.5","Cell RNA - Karpas-707 [nTPM]":"48.6","Cell RNA - LHCN-M2 [nTPM]":"7.0","Cell RNA - MCF7 [nTPM]":"6.5","Cell RNA - MOLT-4 [nTPM]":"20.3","Cell RNA - NB-4 [nTPM]":"7.9","Cell RNA - NTERA-2 [nTPM]":"3.4","Cell RNA - OE19 [nTPM]":"3.5","Cell RNA - PC-3 [nTPM]":"2.3","Cell RNA - REH [nTPM]":"10.8","Cell RNA - RH-30 [nTPM]":"9.3","Cell RNA - RPMI-8226 [nTPM]":"21.9","Cell RNA - RPTEC TERT1 [nTPM]":"8.1","Cell RNA - RT4 [nTPM]":"2.0","Cell RNA - SCLC-21H [nTPM]":"4.4","Cell RNA - SH-SY5Y [nTPM]":"3.9","Cell RNA - SiHa [nTPM]":"4.6","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"5.4","Cell RNA - SuSa [nTPM]":"9.6","Cell RNA - T-47d [nTPM]":"23.2","Cell RNA - THP-1 [nTPM]":"3.9","Cell RNA - TIME [nTPM]":"0.8","Cell RNA - U-138 MG [nTPM]":"8.3","Cell RNA - U-2 OS [nTPM]":"4.2","Cell RNA - U-2197 [nTPM]":"2.8","Cell RNA - U-251 MG [nTPM]":"4.1","Cell RNA - U-266\/70 [nTPM]":"15.6","Cell RNA - U-266\/84 [nTPM]":"15.0","Cell RNA - U-698 [nTPM]":"48.3","Cell RNA - U-87 MG [nTPM]":"9.1","Cell RNA - U-937 [nTPM]":"11.7","Cell RNA - WM-115 [nTPM]":"14.0","Blood RNA - basophil [nTPM]":"24.7","Blood RNA - classical monocyte [nTPM]":"9.9","Blood RNA - eosinophil [nTPM]":"8.1","Blood RNA - gdT-cell [nTPM]":"39.4","Blood RNA - intermediate monocyte [nTPM]":"12.0","Blood RNA - MAIT T-cell [nTPM]":"51.4","Blood RNA - memory B-cell [nTPM]":"102.9","Blood RNA - memory CD4 T-cell [nTPM]":"37.1","Blood RNA - memory CD8 T-cell [nTPM]":"39.9","Blood RNA - myeloid DC [nTPM]":"18.6","Blood RNA - naive B-cell [nTPM]":"113.5","Blood RNA - naive CD4 T-cell [nTPM]":"36.3","Blood RNA - naive CD8 T-cell [nTPM]":"44.2","Blood RNA - neutrophil [nTPM]":"3.2","Blood RNA - NK-cell [nTPM]":"27.6","Blood RNA - non-classical monocyte [nTPM]":"3.6","Blood RNA - plasmacytoid DC [nTPM]":"131.3","Blood RNA - T-reg [nTPM]":"46.9","Blood RNA - total PBMC [nTPM]":"24.5","Brain RNA - amygdala [nTPM]":"23.3","Brain RNA - basal ganglia [nTPM]":"26.3","Brain RNA - cerebellum [nTPM]":"22.5","Brain RNA - cerebral cortex [nTPM]":"31.2","Brain RNA - hippocampal formation [nTPM]":"26.5","Brain RNA - hypothalamus [nTPM]":"23.9","Brain RNA - medulla oblongata [nTPM]":"19.9","Brain RNA - midbrain [nTPM]":"22.3","Brain RNA - pons [nTPM]":"22.9","Brain RNA - spinal cord [nTPM]":"22.1","Brain RNA - thalamus [nTPM]":"27.7","Brain RNA - white matter [nTPM]":"33.2","Single Cell Type RNA - Adipocytes [nTPM]":"20.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.4","Single Cell Type RNA - Astrocytes [nTPM]":"105.4","Single Cell Type RNA - B-cells [nTPM]":"124.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"29.6","Single Cell Type RNA - Bipolar cells [nTPM]":"109.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"42.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"25.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"512.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"13.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"49.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.5","Single Cell Type RNA - dendritic cells [nTPM]":"153.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"156.5","Single Cell Type RNA - Ductal cells [nTPM]":"7.0","Single Cell Type RNA - Early spermatids [nTPM]":"7.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"37.2","Single Cell Type RNA - Endothelial cells [nTPM]":"27.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"34.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"89.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.2","Single Cell Type RNA - Fibroblasts [nTPM]":"42.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.0","Single Cell Type RNA - granulocytes [nTPM]":"19.0","Single Cell Type RNA - Granulosa cells [nTPM]":"32.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"24.7","Single Cell Type RNA - Hepatocytes [nTPM]":"30.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.9","Single Cell Type RNA - Horizontal cells [nTPM]":"85.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"145.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.5","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"14.5","Single Cell Type RNA - Langerhans cells [nTPM]":"16.4","Single Cell Type RNA - Late spermatids [nTPM]":"10.5","Single Cell Type RNA - Leydig cells [nTPM]":"23.9","Single Cell Type RNA - Macrophages [nTPM]":"27.5","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"40.3","Single Cell Type RNA - monocytes [nTPM]":"75.6","Single Cell Type RNA - Muller glia cells [nTPM]":"21.8","Single Cell Type RNA - NK-cells [nTPM]":"80.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"100.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"54.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.6","Single Cell Type RNA - Paneth cells [nTPM]":"9.2","Single Cell Type RNA - Peritubular cells [nTPM]":"31.6","Single Cell Type RNA - Plasma cells [nTPM]":"82.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"32.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"47.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.8","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"38.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"36.4","Single Cell Type RNA - Spermatocytes [nTPM]":"38.2","Single Cell Type RNA - Spermatogonia [nTPM]":"22.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"71.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.9","Single Cell Type RNA - T-cells [nTPM]":"70.1","Single Cell Type RNA - Theca cells [nTPM]":"45.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.1","Single Cell Type RNA - Urothelial cells [nTPM]":"6.7"},{"Gene":"PPOX","Gene synonym":["PPO","VP"],"Ensembl":"ENSG00000143224","Gene description":"Protoporphyrinogen oxidase","Uniprot":["P50336"],"Chromosome":"1","Position":"161166056-161178013","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Heme biosynthesis","Porphyrin biosynthesis"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"65.9","Respiratory ciliated cells":"84.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030123"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"HPA030123":"AB_10603987"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.89e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.3","Tissue RNA - adrenal gland [nTPM]":"17.1","Tissue RNA - amygdala [nTPM]":"24.2","Tissue RNA - appendix [nTPM]":"3.5","Tissue RNA - basal ganglia [nTPM]":"24.5","Tissue RNA - bone marrow [nTPM]":"25.2","Tissue RNA - breast [nTPM]":"10.3","Tissue RNA - cerebellum [nTPM]":"25.2","Tissue RNA - cerebral cortex [nTPM]":"38.2","Tissue RNA - cervix [nTPM]":"14.5","Tissue RNA - choroid plexus [nTPM]":"24.7","Tissue RNA - colon [nTPM]":"12.7","Tissue RNA - duodenum [nTPM]":"3.9","Tissue RNA - endometrium 1 [nTPM]":"10.9","Tissue RNA - epididymis [nTPM]":"8.3","Tissue RNA - esophagus [nTPM]":"8.9","Tissue RNA - fallopian tube [nTPM]":"22.0","Tissue RNA - gallbladder [nTPM]":"4.7","Tissue RNA - heart muscle [nTPM]":"13.1","Tissue RNA - hippocampal formation [nTPM]":"24.4","Tissue RNA - hypothalamus [nTPM]":"24.7","Tissue RNA - kidney [nTPM]":"15.5","Tissue RNA - liver [nTPM]":"11.5","Tissue RNA - lung [nTPM]":"8.6","Tissue RNA - lymph node [nTPM]":"5.7","Tissue RNA - medulla oblongata [nTPM]":"25.0","Tissue RNA - midbrain [nTPM]":"25.0","Tissue RNA - ovary [nTPM]":"13.8","Tissue RNA - pancreas [nTPM]":"10.8","Tissue RNA - parathyroid gland [nTPM]":"7.2","Tissue RNA - pituitary gland [nTPM]":"13.7","Tissue RNA - placenta [nTPM]":"6.5","Tissue RNA - pons [nTPM]":"24.6","Tissue RNA - prostate [nTPM]":"13.4","Tissue RNA - rectum [nTPM]":"3.9","Tissue RNA - retina [nTPM]":"12.6","Tissue RNA - salivary gland [nTPM]":"8.7","Tissue RNA - seminal vesicle [nTPM]":"7.7","Tissue RNA - skeletal muscle [nTPM]":"7.6","Tissue RNA - skin 1 [nTPM]":"11.2","Tissue RNA - small intestine [nTPM]":"8.5","Tissue RNA - smooth muscle [nTPM]":"6.6","Tissue RNA - spinal cord [nTPM]":"25.0","Tissue RNA - spleen [nTPM]":"13.6","Tissue RNA - stomach 1 [nTPM]":"10.9","Tissue RNA - testis [nTPM]":"6.9","Tissue RNA - thalamus [nTPM]":"24.0","Tissue RNA - thymus [nTPM]":"5.0","Tissue RNA - thyroid gland [nTPM]":"11.9","Tissue RNA - tongue [nTPM]":"5.6","Tissue RNA - tonsil [nTPM]":"5.2","Tissue RNA - urinary bladder [nTPM]":"11.6","Tissue RNA - vagina [nTPM]":"9.6","Tissue RNA - white matter [nTPM]":"25.4","Cell RNA - A-431 [nTPM]":"10.0","Cell RNA - A549 [nTPM]":"8.0","Cell RNA - AF22 [nTPM]":"12.7","Cell RNA - AN3-CA [nTPM]":"8.5","Cell RNA - ASC diff [nTPM]":"10.4","Cell RNA - ASC TERT1 [nTPM]":"9.3","Cell RNA - BEWO [nTPM]":"3.5","Cell RNA - BJ [nTPM]":"5.9","Cell RNA - BJ hTERT+ [nTPM]":"5.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.3","Cell RNA - CACO-2 [nTPM]":"10.4","Cell RNA - CAPAN-2 [nTPM]":"9.3","Cell RNA - Daudi [nTPM]":"7.4","Cell RNA - EFO-21 [nTPM]":"14.3","Cell RNA - fHDF\/TERT166 [nTPM]":"5.3","Cell RNA - GAMG [nTPM]":"4.1","Cell RNA - HaCaT [nTPM]":"6.3","Cell RNA - HAP1 [nTPM]":"9.8","Cell RNA - HBEC3-KT [nTPM]":"8.8","Cell RNA - HBF TERT88 [nTPM]":"7.1","Cell RNA - HDLM-2 [nTPM]":"4.6","Cell RNA - HEK 293 [nTPM]":"20.3","Cell RNA - HEL [nTPM]":"9.0","Cell RNA - HeLa [nTPM]":"18.9","Cell RNA - Hep G2 [nTPM]":"23.9","Cell RNA - HHSteC [nTPM]":"8.6","Cell RNA - HL-60 [nTPM]":"3.0","Cell RNA - HMC-1 [nTPM]":"4.6","Cell RNA - HSkMC [nTPM]":"7.6","Cell RNA - hTCEpi [nTPM]":"11.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.3","Cell RNA - hTERT-HME1 [nTPM]":"9.4","Cell RNA - hTERT-RPE1 [nTPM]":"9.4","Cell RNA - HUVEC TERT2 [nTPM]":"14.7","Cell RNA - JURKAT [nTPM]":"7.0","Cell RNA - K-562 [nTPM]":"22.8","Cell RNA - Karpas-707 [nTPM]":"11.2","Cell RNA - LHCN-M2 [nTPM]":"5.6","Cell RNA - MCF7 [nTPM]":"9.2","Cell RNA - MOLT-4 [nTPM]":"12.0","Cell RNA - NB-4 [nTPM]":"8.6","Cell RNA - NTERA-2 [nTPM]":"8.2","Cell RNA - OE19 [nTPM]":"11.2","Cell RNA - PC-3 [nTPM]":"18.8","Cell RNA - REH [nTPM]":"13.6","Cell RNA - RH-30 [nTPM]":"8.2","Cell RNA - RPMI-8226 [nTPM]":"16.7","Cell RNA - RPTEC TERT1 [nTPM]":"15.1","Cell RNA - RT4 [nTPM]":"4.2","Cell RNA - SCLC-21H [nTPM]":"9.8","Cell RNA - SH-SY5Y [nTPM]":"14.7","Cell RNA - SiHa [nTPM]":"6.6","Cell RNA - SK-BR-3 [nTPM]":"10.3","Cell RNA - SK-MEL-30 [nTPM]":"12.0","Cell RNA - SuSa [nTPM]":"14.6","Cell RNA - T-47d [nTPM]":"19.9","Cell RNA - THP-1 [nTPM]":"9.5","Cell RNA - TIME [nTPM]":"5.7","Cell RNA - U-138 MG [nTPM]":"6.5","Cell RNA - U-2 OS [nTPM]":"7.1","Cell RNA - U-2197 [nTPM]":"6.5","Cell RNA - U-251 MG [nTPM]":"7.5","Cell RNA - U-266\/70 [nTPM]":"19.4","Cell RNA - U-266\/84 [nTPM]":"15.3","Cell RNA - U-698 [nTPM]":"10.5","Cell RNA - U-87 MG [nTPM]":"6.8","Cell RNA - U-937 [nTPM]":"6.0","Cell RNA - WM-115 [nTPM]":"4.9","Blood RNA - basophil [nTPM]":"6.3","Blood RNA - classical monocyte [nTPM]":"7.2","Blood RNA - eosinophil [nTPM]":"5.3","Blood RNA - gdT-cell [nTPM]":"10.4","Blood RNA - intermediate monocyte [nTPM]":"7.6","Blood RNA - MAIT T-cell [nTPM]":"7.2","Blood RNA - memory B-cell [nTPM]":"9.0","Blood RNA - memory CD4 T-cell [nTPM]":"7.8","Blood RNA - memory CD8 T-cell [nTPM]":"7.6","Blood RNA - myeloid DC [nTPM]":"10.4","Blood RNA - naive B-cell [nTPM]":"8.2","Blood RNA - naive CD4 T-cell [nTPM]":"6.8","Blood RNA - naive CD8 T-cell [nTPM]":"6.9","Blood RNA - neutrophil [nTPM]":"2.9","Blood RNA - NK-cell [nTPM]":"12.0","Blood RNA - non-classical monocyte [nTPM]":"5.2","Blood RNA - plasmacytoid DC [nTPM]":"6.6","Blood RNA - T-reg [nTPM]":"16.1","Blood RNA - total PBMC [nTPM]":"7.8","Brain RNA - amygdala [nTPM]":"24.2","Brain RNA - basal ganglia [nTPM]":"24.5","Brain RNA - cerebellum [nTPM]":"25.2","Brain RNA - cerebral cortex [nTPM]":"38.2","Brain RNA - hippocampal formation [nTPM]":"24.4","Brain RNA - hypothalamus [nTPM]":"24.7","Brain RNA - medulla oblongata [nTPM]":"25.0","Brain RNA - midbrain [nTPM]":"25.0","Brain RNA - pons [nTPM]":"24.6","Brain RNA - spinal cord [nTPM]":"25.0","Brain RNA - thalamus [nTPM]":"24.0","Brain RNA - white matter [nTPM]":"25.4","Single Cell Type RNA - Adipocytes [nTPM]":"10.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.7","Single Cell Type RNA - Astrocytes [nTPM]":"10.4","Single Cell Type RNA - B-cells [nTPM]":"9.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"18.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"15.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"21.4","Single Cell Type RNA - dendritic cells [nTPM]":"10.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"9.5","Single Cell Type RNA - Early spermatids [nTPM]":"9.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"39.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.9","Single Cell Type RNA - Endothelial cells [nTPM]":"8.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"65.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.4","Single Cell Type RNA - Fibroblasts [nTPM]":"9.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.6","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"12.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.9","Single Cell Type RNA - Hepatocytes [nTPM]":"6.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.3","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.3","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"4.7","Single Cell Type RNA - Langerhans cells [nTPM]":"8.4","Single Cell Type RNA - Late spermatids [nTPM]":"12.1","Single Cell Type RNA - Leydig cells [nTPM]":"10.2","Single Cell Type RNA - Macrophages [nTPM]":"8.0","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"8.1","Single Cell Type RNA - Muller glia cells [nTPM]":"10.4","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.3","Single Cell Type RNA - Paneth cells [nTPM]":"3.8","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"16.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"84.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.6","Single Cell Type RNA - Spermatocytes [nTPM]":"12.8","Single Cell Type RNA - Spermatogonia [nTPM]":"9.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.4","Single Cell Type RNA - T-cells [nTPM]":"10.6","Single Cell Type RNA - Theca cells [nTPM]":"11.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.5","Single Cell Type RNA - Urothelial cells [nTPM]":"6.2"},{"Gene":"PPP1CB","Gene synonym":["MP","PP-1B","PP1B","PP1beta","PP1c","PPP1beta"],"Ensembl":"ENSG00000213639","Gene description":"Protein phosphatase 1 catalytic subunit beta","Uniprot":["P62140"],"Chromosome":"2","Position":"28751640-28802940","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Biological rhythms","Carbohydrate metabolism","Cell cycle","Cell division","Glycogen metabolism"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"985.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022558","HPA065425","CAB069426"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3800000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB022558":null,"CAB069426":null,"HPA065425":"AB_2685489"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.52e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Tissue RNA - adipose tissue [nTPM]":"90.9","Tissue RNA - adrenal gland [nTPM]":"75.2","Tissue RNA - amygdala [nTPM]":"55.8","Tissue RNA - appendix [nTPM]":"74.7","Tissue RNA - basal ganglia [nTPM]":"73.5","Tissue RNA - bone marrow [nTPM]":"119.1","Tissue RNA - breast [nTPM]":"110.5","Tissue RNA - cerebellum [nTPM]":"55.6","Tissue RNA - cerebral cortex [nTPM]":"74.9","Tissue RNA - cervix [nTPM]":"148.6","Tissue RNA - choroid plexus [nTPM]":"67.8","Tissue RNA - colon [nTPM]":"109.2","Tissue RNA - duodenum [nTPM]":"84.8","Tissue RNA - endometrium 1 [nTPM]":"138.4","Tissue RNA - epididymis [nTPM]":"104.0","Tissue RNA - esophagus [nTPM]":"245.7","Tissue RNA - fallopian tube [nTPM]":"113.5","Tissue RNA - gallbladder [nTPM]":"103.1","Tissue RNA - heart muscle [nTPM]":"185.2","Tissue RNA - hippocampal formation [nTPM]":"54.3","Tissue RNA - hypothalamus [nTPM]":"73.8","Tissue RNA - kidney [nTPM]":"84.4","Tissue RNA - liver [nTPM]":"70.5","Tissue RNA - lung [nTPM]":"73.3","Tissue RNA - lymph node [nTPM]":"60.4","Tissue RNA - medulla oblongata [nTPM]":"73.9","Tissue RNA - midbrain [nTPM]":"61.2","Tissue RNA - ovary [nTPM]":"92.7","Tissue RNA - pancreas [nTPM]":"76.2","Tissue RNA - parathyroid gland [nTPM]":"126.9","Tissue RNA - pituitary gland [nTPM]":"45.9","Tissue RNA - placenta [nTPM]":"74.8","Tissue RNA - pons [nTPM]":"74.5","Tissue RNA - prostate [nTPM]":"149.1","Tissue RNA - rectum [nTPM]":"92.9","Tissue RNA - retina [nTPM]":"70.8","Tissue RNA - salivary gland [nTPM]":"114.6","Tissue RNA - seminal vesicle [nTPM]":"123.4","Tissue RNA - skeletal muscle [nTPM]":"386.0","Tissue RNA - skin 1 [nTPM]":"73.7","Tissue RNA - small intestine [nTPM]":"76.0","Tissue RNA - smooth muscle [nTPM]":"159.7","Tissue RNA - spinal cord [nTPM]":"71.8","Tissue RNA - spleen [nTPM]":"65.8","Tissue RNA - stomach 1 [nTPM]":"81.7","Tissue RNA - testis [nTPM]":"47.6","Tissue RNA - thalamus [nTPM]":"63.5","Tissue RNA - thymus [nTPM]":"71.3","Tissue RNA - thyroid gland [nTPM]":"78.8","Tissue RNA - tongue [nTPM]":"262.8","Tissue RNA - tonsil [nTPM]":"91.1","Tissue RNA - urinary bladder [nTPM]":"118.0","Tissue RNA - vagina [nTPM]":"104.1","Tissue RNA - white matter [nTPM]":"88.2","Cell RNA - A-431 [nTPM]":"186.0","Cell RNA - A549 [nTPM]":"114.6","Cell RNA - AF22 [nTPM]":"391.1","Cell RNA - AN3-CA [nTPM]":"121.7","Cell RNA - ASC diff [nTPM]":"130.8","Cell RNA - ASC TERT1 [nTPM]":"121.0","Cell RNA - BEWO [nTPM]":"227.0","Cell RNA - BJ [nTPM]":"97.7","Cell RNA - BJ hTERT+ [nTPM]":"110.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"92.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"91.0","Cell RNA - CACO-2 [nTPM]":"102.6","Cell RNA - CAPAN-2 [nTPM]":"106.9","Cell RNA - Daudi [nTPM]":"147.5","Cell RNA - EFO-21 [nTPM]":"119.2","Cell RNA - fHDF\/TERT166 [nTPM]":"101.5","Cell RNA - GAMG [nTPM]":"102.7","Cell RNA - HaCaT [nTPM]":"111.4","Cell RNA - HAP1 [nTPM]":"112.6","Cell RNA - HBEC3-KT [nTPM]":"129.9","Cell RNA - HBF TERT88 [nTPM]":"109.8","Cell RNA - HDLM-2 [nTPM]":"235.9","Cell RNA - HEK 293 [nTPM]":"58.2","Cell RNA - HEL [nTPM]":"111.3","Cell RNA - HeLa [nTPM]":"130.1","Cell RNA - Hep G2 [nTPM]":"111.5","Cell RNA - HHSteC [nTPM]":"284.3","Cell RNA - HL-60 [nTPM]":"127.8","Cell RNA - HMC-1 [nTPM]":"50.5","Cell RNA - HSkMC [nTPM]":"93.5","Cell RNA - hTCEpi [nTPM]":"181.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"100.1","Cell RNA - hTERT-HME1 [nTPM]":"207.8","Cell RNA - hTERT-RPE1 [nTPM]":"97.4","Cell RNA - HUVEC TERT2 [nTPM]":"113.8","Cell RNA - JURKAT [nTPM]":"77.0","Cell RNA - K-562 [nTPM]":"103.6","Cell RNA - Karpas-707 [nTPM]":"140.4","Cell RNA - LHCN-M2 [nTPM]":"123.3","Cell RNA - MCF7 [nTPM]":"93.2","Cell RNA - MOLT-4 [nTPM]":"136.9","Cell RNA - NB-4 [nTPM]":"110.3","Cell RNA - NTERA-2 [nTPM]":"128.3","Cell RNA - OE19 [nTPM]":"141.8","Cell RNA - PC-3 [nTPM]":"89.8","Cell RNA - REH [nTPM]":"132.2","Cell RNA - RH-30 [nTPM]":"344.9","Cell RNA - RPMI-8226 [nTPM]":"112.7","Cell RNA - RPTEC TERT1 [nTPM]":"304.3","Cell RNA - RT4 [nTPM]":"220.6","Cell RNA - SCLC-21H [nTPM]":"106.7","Cell RNA - SH-SY5Y [nTPM]":"131.3","Cell RNA - SiHa [nTPM]":"151.4","Cell RNA - SK-BR-3 [nTPM]":"166.2","Cell RNA - SK-MEL-30 [nTPM]":"136.2","Cell RNA - SuSa [nTPM]":"111.4","Cell RNA - T-47d [nTPM]":"80.4","Cell RNA - THP-1 [nTPM]":"70.6","Cell RNA - TIME [nTPM]":"137.6","Cell RNA - U-138 MG [nTPM]":"122.6","Cell RNA - U-2 OS [nTPM]":"134.6","Cell RNA - U-2197 [nTPM]":"89.3","Cell RNA - U-251 MG [nTPM]":"119.0","Cell RNA - U-266\/70 [nTPM]":"100.4","Cell RNA - U-266\/84 [nTPM]":"171.0","Cell RNA - U-698 [nTPM]":"299.8","Cell RNA - U-87 MG [nTPM]":"130.1","Cell RNA - U-937 [nTPM]":"135.0","Cell RNA - WM-115 [nTPM]":"93.5","Blood RNA - basophil [nTPM]":"72.4","Blood RNA - classical monocyte [nTPM]":"59.4","Blood RNA - eosinophil [nTPM]":"84.9","Blood RNA - gdT-cell [nTPM]":"39.8","Blood RNA - intermediate monocyte [nTPM]":"96.7","Blood RNA - MAIT T-cell [nTPM]":"50.8","Blood RNA - memory B-cell [nTPM]":"38.6","Blood RNA - memory CD4 T-cell [nTPM]":"59.3","Blood RNA - memory CD8 T-cell [nTPM]":"46.8","Blood RNA - myeloid DC [nTPM]":"65.4","Blood RNA - naive B-cell [nTPM]":"31.6","Blood RNA - naive CD4 T-cell [nTPM]":"51.8","Blood RNA - naive CD8 T-cell [nTPM]":"58.8","Blood RNA - neutrophil [nTPM]":"103.6","Blood RNA - NK-cell [nTPM]":"61.4","Blood RNA - non-classical monocyte [nTPM]":"115.2","Blood RNA - plasmacytoid DC [nTPM]":"49.8","Blood RNA - T-reg [nTPM]":"74.3","Blood RNA - total PBMC [nTPM]":"52.8","Brain RNA - amygdala [nTPM]":"55.8","Brain RNA - basal ganglia [nTPM]":"73.5","Brain RNA - cerebellum [nTPM]":"55.6","Brain RNA - cerebral cortex [nTPM]":"74.9","Brain RNA - hippocampal formation [nTPM]":"54.3","Brain RNA - hypothalamus [nTPM]":"73.8","Brain RNA - medulla oblongata [nTPM]":"73.9","Brain RNA - midbrain [nTPM]":"61.2","Brain RNA - pons [nTPM]":"74.5","Brain RNA - spinal cord [nTPM]":"71.8","Brain RNA - thalamus [nTPM]":"63.5","Brain RNA - white matter [nTPM]":"88.2","Single Cell Type RNA - Adipocytes [nTPM]":"172.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"93.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"80.6","Single Cell Type RNA - Astrocytes [nTPM]":"59.4","Single Cell Type RNA - B-cells [nTPM]":"147.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"492.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"176.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"101.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"64.9","Single Cell Type RNA - Bipolar cells [nTPM]":"62.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"208.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"117.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"352.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"112.9","Single Cell Type RNA - Club cells [nTPM]":"124.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"310.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"129.6","Single Cell Type RNA - dendritic cells [nTPM]":"210.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"324.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"244.6","Single Cell Type RNA - Ductal cells [nTPM]":"297.0","Single Cell Type RNA - Early spermatids [nTPM]":"514.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"330.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"245.7","Single Cell Type RNA - Endothelial cells [nTPM]":"129.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"283.0","Single Cell Type RNA - Erythroid cells [nTPM]":"200.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"68.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"210.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"202.1","Single Cell Type RNA - Fibroblasts [nTPM]":"147.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"78.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"258.9","Single Cell Type RNA - granulocytes [nTPM]":"146.6","Single Cell Type RNA - Granulosa cells [nTPM]":"91.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"137.8","Single Cell Type RNA - Hepatocytes [nTPM]":"108.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"114.7","Single Cell Type RNA - Horizontal cells [nTPM]":"163.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"71.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"144.2","Single Cell Type RNA - Ionocytes [nTPM]":"111.9","Single Cell Type RNA - Kupffer cells [nTPM]":"182.6","Single Cell Type RNA - Langerhans cells [nTPM]":"985.1","Single Cell Type RNA - Late spermatids [nTPM]":"406.2","Single Cell Type RNA - Leydig cells [nTPM]":"196.7","Single Cell Type RNA - Macrophages [nTPM]":"238.1","Single Cell Type RNA - Melanocytes [nTPM]":"336.2","Single Cell Type RNA - Microglial cells [nTPM]":"59.0","Single Cell Type RNA - monocytes [nTPM]":"137.9","Single Cell Type RNA - Muller glia cells [nTPM]":"116.6","Single Cell Type RNA - NK-cells [nTPM]":"55.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"64.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"68.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"236.8","Single Cell Type RNA - Paneth cells [nTPM]":"181.3","Single Cell Type RNA - Peritubular cells [nTPM]":"302.0","Single Cell Type RNA - Plasma cells [nTPM]":"100.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"364.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"106.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"227.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"213.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"65.2","Single Cell Type RNA - Sertoli cells [nTPM]":"631.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"225.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"264.8","Single Cell Type RNA - Spermatocytes [nTPM]":"55.2","Single Cell Type RNA - Spermatogonia [nTPM]":"66.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"135.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"458.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"392.9","Single Cell Type RNA - T-cells [nTPM]":"237.7","Single Cell Type RNA - Theca cells [nTPM]":"65.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"154.4","Single Cell Type RNA - Urothelial cells [nTPM]":"498.9"},{"Gene":"PPP2CA","Gene synonym":["PP2AC","PP2Calpha"],"Ensembl":"ENSG00000113575","Gene description":"Protein phosphatase 2 catalytic subunit alpha","Uniprot":["P67775"],"Chromosome":"5","Position":"134194332-134226073","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Meiosis"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003848","HPA043236"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB003848":"AB_562203","HPA043236":"AB_2678379"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.33e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Tissue RNA - adipose tissue [nTPM]":"47.9","Tissue RNA - adrenal gland [nTPM]":"53.1","Tissue RNA - amygdala [nTPM]":"52.1","Tissue RNA - appendix [nTPM]":"42.9","Tissue RNA - basal ganglia [nTPM]":"55.1","Tissue RNA - bone marrow [nTPM]":"124.8","Tissue RNA - breast [nTPM]":"46.6","Tissue RNA - cerebellum [nTPM]":"60.6","Tissue RNA - cerebral cortex [nTPM]":"66.3","Tissue RNA - cervix [nTPM]":"38.9","Tissue RNA - choroid plexus [nTPM]":"44.9","Tissue RNA - colon [nTPM]":"51.4","Tissue RNA - duodenum [nTPM]":"46.1","Tissue RNA - endometrium 1 [nTPM]":"46.6","Tissue RNA - epididymis [nTPM]":"36.1","Tissue RNA - esophagus [nTPM]":"71.5","Tissue RNA - fallopian tube [nTPM]":"39.0","Tissue RNA - gallbladder [nTPM]":"44.6","Tissue RNA - heart muscle [nTPM]":"90.1","Tissue RNA - hippocampal formation [nTPM]":"57.8","Tissue RNA - hypothalamus [nTPM]":"53.5","Tissue RNA - kidney [nTPM]":"57.3","Tissue RNA - liver [nTPM]":"62.1","Tissue RNA - lung [nTPM]":"39.4","Tissue RNA - lymph node [nTPM]":"58.6","Tissue RNA - medulla oblongata [nTPM]":"48.6","Tissue RNA - midbrain [nTPM]":"51.4","Tissue RNA - ovary [nTPM]":"30.0","Tissue RNA - pancreas [nTPM]":"44.3","Tissue RNA - parathyroid gland [nTPM]":"87.1","Tissue RNA - pituitary gland [nTPM]":"26.1","Tissue RNA - placenta [nTPM]":"52.2","Tissue RNA - pons [nTPM]":"53.7","Tissue RNA - prostate [nTPM]":"37.8","Tissue RNA - rectum [nTPM]":"47.1","Tissue RNA - retina [nTPM]":"58.6","Tissue RNA - salivary gland [nTPM]":"36.5","Tissue RNA - seminal vesicle [nTPM]":"40.4","Tissue RNA - skeletal muscle [nTPM]":"75.3","Tissue RNA - skin 1 [nTPM]":"54.1","Tissue RNA - small intestine [nTPM]":"44.5","Tissue RNA - smooth muscle [nTPM]":"57.8","Tissue RNA - spinal cord [nTPM]":"54.7","Tissue RNA - spleen [nTPM]":"40.0","Tissue RNA - stomach 1 [nTPM]":"41.3","Tissue RNA - testis [nTPM]":"34.7","Tissue RNA - thalamus [nTPM]":"53.6","Tissue RNA - thymus [nTPM]":"92.4","Tissue RNA - thyroid gland [nTPM]":"48.1","Tissue RNA - tongue [nTPM]":"73.1","Tissue RNA - tonsil [nTPM]":"76.7","Tissue RNA - urinary bladder [nTPM]":"75.4","Tissue RNA - vagina [nTPM]":"41.0","Tissue RNA - white matter [nTPM]":"59.5","Cell RNA - A-431 [nTPM]":"157.0","Cell RNA - A549 [nTPM]":"128.8","Cell RNA - AF22 [nTPM]":"180.8","Cell RNA - AN3-CA [nTPM]":"97.9","Cell RNA - ASC diff [nTPM]":"92.1","Cell RNA - ASC TERT1 [nTPM]":"98.2","Cell RNA - BEWO [nTPM]":"126.2","Cell RNA - BJ [nTPM]":"144.1","Cell RNA - BJ hTERT+ [nTPM]":"123.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"214.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"215.4","Cell RNA - CACO-2 [nTPM]":"249.1","Cell RNA - CAPAN-2 [nTPM]":"119.6","Cell RNA - Daudi [nTPM]":"136.5","Cell RNA - EFO-21 [nTPM]":"131.7","Cell RNA - fHDF\/TERT166 [nTPM]":"134.4","Cell RNA - GAMG [nTPM]":"242.9","Cell RNA - HaCaT [nTPM]":"79.7","Cell RNA - HAP1 [nTPM]":"175.6","Cell RNA - HBEC3-KT [nTPM]":"208.6","Cell RNA - HBF TERT88 [nTPM]":"250.2","Cell RNA - HDLM-2 [nTPM]":"123.9","Cell RNA - HEK 293 [nTPM]":"100.1","Cell RNA - HEL [nTPM]":"96.9","Cell RNA - HeLa [nTPM]":"142.4","Cell RNA - Hep G2 [nTPM]":"156.5","Cell RNA - HHSteC [nTPM]":"136.3","Cell RNA - HL-60 [nTPM]":"97.1","Cell RNA - HMC-1 [nTPM]":"84.2","Cell RNA - HSkMC [nTPM]":"91.7","Cell RNA - hTCEpi [nTPM]":"141.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"169.0","Cell RNA - hTERT-HME1 [nTPM]":"166.6","Cell RNA - hTERT-RPE1 [nTPM]":"107.0","Cell RNA - HUVEC TERT2 [nTPM]":"153.5","Cell RNA - JURKAT [nTPM]":"135.1","Cell RNA - K-562 [nTPM]":"97.2","Cell RNA - Karpas-707 [nTPM]":"99.1","Cell RNA - LHCN-M2 [nTPM]":"165.1","Cell RNA - MCF7 [nTPM]":"112.5","Cell RNA - MOLT-4 [nTPM]":"154.9","Cell RNA - NB-4 [nTPM]":"95.0","Cell RNA - NTERA-2 [nTPM]":"98.9","Cell RNA - OE19 [nTPM]":"123.6","Cell RNA - PC-3 [nTPM]":"77.3","Cell RNA - REH [nTPM]":"136.5","Cell RNA - RH-30 [nTPM]":"179.6","Cell RNA - RPMI-8226 [nTPM]":"132.6","Cell RNA - RPTEC TERT1 [nTPM]":"130.0","Cell RNA - RT4 [nTPM]":"173.4","Cell RNA - SCLC-21H [nTPM]":"142.9","Cell RNA - SH-SY5Y [nTPM]":"99.6","Cell RNA - SiHa [nTPM]":"148.9","Cell RNA - SK-BR-3 [nTPM]":"55.1","Cell RNA - SK-MEL-30 [nTPM]":"166.9","Cell RNA - SuSa [nTPM]":"179.7","Cell RNA - T-47d [nTPM]":"112.2","Cell RNA - THP-1 [nTPM]":"112.3","Cell RNA - TIME [nTPM]":"109.2","Cell RNA - U-138 MG [nTPM]":"123.3","Cell RNA - U-2 OS [nTPM]":"69.1","Cell RNA - U-2197 [nTPM]":"99.6","Cell RNA - U-251 MG [nTPM]":"206.5","Cell RNA - U-266\/70 [nTPM]":"88.5","Cell RNA - U-266\/84 [nTPM]":"171.6","Cell RNA - U-698 [nTPM]":"217.0","Cell RNA - U-87 MG [nTPM]":"83.2","Cell RNA - U-937 [nTPM]":"125.9","Cell RNA - WM-115 [nTPM]":"130.3","Blood RNA - basophil [nTPM]":"43.0","Blood RNA - classical monocyte [nTPM]":"64.7","Blood RNA - eosinophil [nTPM]":"75.6","Blood RNA - gdT-cell [nTPM]":"46.8","Blood RNA - intermediate monocyte [nTPM]":"63.1","Blood RNA - MAIT T-cell [nTPM]":"59.2","Blood RNA - memory B-cell [nTPM]":"53.1","Blood RNA - memory CD4 T-cell [nTPM]":"53.2","Blood RNA - memory CD8 T-cell [nTPM]":"62.5","Blood RNA - myeloid DC [nTPM]":"77.3","Blood RNA - naive B-cell [nTPM]":"54.7","Blood RNA - naive CD4 T-cell [nTPM]":"60.6","Blood RNA - naive CD8 T-cell [nTPM]":"57.2","Blood RNA - neutrophil [nTPM]":"71.3","Blood RNA - NK-cell [nTPM]":"75.5","Blood RNA - non-classical monocyte [nTPM]":"67.0","Blood RNA - plasmacytoid DC [nTPM]":"41.5","Blood RNA - T-reg [nTPM]":"72.4","Blood RNA - total PBMC [nTPM]":"95.8","Brain RNA - amygdala [nTPM]":"52.1","Brain RNA - basal ganglia [nTPM]":"55.1","Brain RNA - cerebellum [nTPM]":"60.6","Brain RNA - cerebral cortex [nTPM]":"66.3","Brain RNA - hippocampal formation [nTPM]":"57.8","Brain RNA - hypothalamus [nTPM]":"53.5","Brain RNA - medulla oblongata [nTPM]":"48.6","Brain RNA - midbrain [nTPM]":"51.4","Brain RNA - pons [nTPM]":"53.7","Brain RNA - spinal cord [nTPM]":"54.7","Brain RNA - thalamus [nTPM]":"53.6","Brain RNA - white matter [nTPM]":"59.5","Single Cell Type RNA - Adipocytes [nTPM]":"58.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"47.6","Single Cell Type RNA - Astrocytes [nTPM]":"27.1","Single Cell Type RNA - B-cells [nTPM]":"103.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"239.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"187.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"90.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"121.8","Single Cell Type RNA - Bipolar cells [nTPM]":"43.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"93.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"53.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"111.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"55.8","Single Cell Type RNA - Club cells [nTPM]":"63.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"57.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"152.1","Single Cell Type RNA - dendritic cells [nTPM]":"89.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"68.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"107.6","Single Cell Type RNA - Ductal cells [nTPM]":"109.7","Single Cell Type RNA - Early spermatids [nTPM]":"34.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"85.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"83.2","Single Cell Type RNA - Endothelial cells [nTPM]":"81.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"87.1","Single Cell Type RNA - Erythroid cells [nTPM]":"89.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"36.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"87.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"171.3","Single Cell Type RNA - Fibroblasts [nTPM]":"78.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"77.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"106.1","Single Cell Type RNA - granulocytes [nTPM]":"62.2","Single Cell Type RNA - Granulosa cells [nTPM]":"44.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"51.8","Single Cell Type RNA - Hepatocytes [nTPM]":"65.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"111.4","Single Cell Type RNA - Horizontal cells [nTPM]":"50.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"35.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"62.0","Single Cell Type RNA - Ionocytes [nTPM]":"69.2","Single Cell Type RNA - Kupffer cells [nTPM]":"88.2","Single Cell Type RNA - Langerhans cells [nTPM]":"194.6","Single Cell Type RNA - Late spermatids [nTPM]":"29.8","Single Cell Type RNA - Leydig cells [nTPM]":"38.5","Single Cell Type RNA - Macrophages [nTPM]":"95.8","Single Cell Type RNA - Melanocytes [nTPM]":"104.9","Single Cell Type RNA - Microglial cells [nTPM]":"24.4","Single Cell Type RNA - monocytes [nTPM]":"115.6","Single Cell Type RNA - Muller glia cells [nTPM]":"62.9","Single Cell Type RNA - NK-cells [nTPM]":"51.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"36.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"48.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"101.7","Single Cell Type RNA - Paneth cells [nTPM]":"56.6","Single Cell Type RNA - Peritubular cells [nTPM]":"45.5","Single Cell Type RNA - Plasma cells [nTPM]":"120.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"143.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"64.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"114.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"53.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"31.4","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"76.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"97.6","Single Cell Type RNA - Spermatocytes [nTPM]":"91.4","Single Cell Type RNA - Spermatogonia [nTPM]":"85.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"112.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"234.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"309.8","Single Cell Type RNA - T-cells [nTPM]":"110.6","Single Cell Type RNA - Theca cells [nTPM]":"53.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"69.7","Single Cell Type RNA - Urothelial cells [nTPM]":"176.7"},{"Gene":"PPP3CA","Gene synonym":["CALN","CALNA","CNA1","PPP2B"],"Ensembl":"ENSG00000138814","Gene description":"Protein phosphatase 3 catalytic subunit alpha","Uniprot":["Q08209"],"Chromosome":"4","Position":"101023409-101348278","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Calmodulin-binding","Hydrolase","Protein phosphatase"],"Disease involvement":["Craniosynostosis","Disease variant","Dwarfism","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"144.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"933.8","Inhibitory neurons":"403.0","Oligodendrocyte precursor cells":"348.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"prostate cancer":"98.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012778","CAB018581"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"94000","Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB018581":"AB_2168324","HPA012778":"AB_1855660"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.82e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"},"Tissue RNA - adipose tissue [nTPM]":"24.7","Tissue RNA - adrenal gland [nTPM]":"17.5","Tissue RNA - amygdala [nTPM]":"48.5","Tissue RNA - appendix [nTPM]":"15.7","Tissue RNA - basal ganglia [nTPM]":"144.1","Tissue RNA - bone marrow [nTPM]":"17.2","Tissue RNA - breast [nTPM]":"20.5","Tissue RNA - cerebellum [nTPM]":"63.2","Tissue RNA - cerebral cortex [nTPM]":"125.6","Tissue RNA - cervix [nTPM]":"17.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"19.5","Tissue RNA - duodenum [nTPM]":"11.6","Tissue RNA - endometrium 1 [nTPM]":"11.8","Tissue RNA - epididymis [nTPM]":"13.1","Tissue RNA - esophagus [nTPM]":"14.4","Tissue RNA - fallopian tube [nTPM]":"13.8","Tissue RNA - gallbladder [nTPM]":"13.3","Tissue RNA - heart muscle [nTPM]":"9.2","Tissue RNA - hippocampal formation [nTPM]":"97.4","Tissue RNA - hypothalamus [nTPM]":"25.0","Tissue RNA - kidney [nTPM]":"11.2","Tissue RNA - liver [nTPM]":"17.0","Tissue RNA - lung [nTPM]":"19.9","Tissue RNA - lymph node [nTPM]":"14.7","Tissue RNA - medulla oblongata [nTPM]":"14.6","Tissue RNA - midbrain [nTPM]":"11.0","Tissue RNA - ovary [nTPM]":"17.9","Tissue RNA - pancreas [nTPM]":"9.4","Tissue RNA - parathyroid gland [nTPM]":"8.9","Tissue RNA - pituitary gland [nTPM]":"9.0","Tissue RNA - placenta [nTPM]":"13.0","Tissue RNA - pons [nTPM]":"15.7","Tissue RNA - prostate [nTPM]":"66.0","Tissue RNA - rectum [nTPM]":"16.1","Tissue RNA - retina [nTPM]":"27.6","Tissue RNA - salivary gland [nTPM]":"22.2","Tissue RNA - seminal vesicle [nTPM]":"38.4","Tissue RNA - skeletal muscle [nTPM]":"51.2","Tissue RNA - skin 1 [nTPM]":"22.9","Tissue RNA - small intestine [nTPM]":"12.9","Tissue RNA - smooth muscle [nTPM]":"15.5","Tissue RNA - spinal cord [nTPM]":"24.7","Tissue RNA - spleen [nTPM]":"14.5","Tissue RNA - stomach 1 [nTPM]":"22.4","Tissue RNA - testis [nTPM]":"10.6","Tissue RNA - thalamus [nTPM]":"23.9","Tissue RNA - thymus [nTPM]":"12.8","Tissue RNA - thyroid gland [nTPM]":"13.2","Tissue RNA - tongue [nTPM]":"29.0","Tissue RNA - tonsil [nTPM]":"18.3","Tissue RNA - urinary bladder [nTPM]":"20.7","Tissue RNA - vagina [nTPM]":"16.0","Tissue RNA - white matter [nTPM]":"54.3","Cell RNA - A-431 [nTPM]":"48.3","Cell RNA - A549 [nTPM]":"33.8","Cell RNA - AF22 [nTPM]":"9.3","Cell RNA - AN3-CA [nTPM]":"18.0","Cell RNA - ASC diff [nTPM]":"50.4","Cell RNA - ASC TERT1 [nTPM]":"37.9","Cell RNA - BEWO [nTPM]":"15.8","Cell RNA - BJ [nTPM]":"51.9","Cell RNA - BJ hTERT+ [nTPM]":"47.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.6","Cell RNA - CACO-2 [nTPM]":"18.3","Cell RNA - CAPAN-2 [nTPM]":"59.0","Cell RNA - Daudi [nTPM]":"22.4","Cell RNA - EFO-21 [nTPM]":"20.9","Cell RNA - fHDF\/TERT166 [nTPM]":"47.6","Cell RNA - GAMG [nTPM]":"25.6","Cell RNA - HaCaT [nTPM]":"23.5","Cell RNA - HAP1 [nTPM]":"33.3","Cell RNA - HBEC3-KT [nTPM]":"69.6","Cell RNA - HBF TERT88 [nTPM]":"34.9","Cell RNA - HDLM-2 [nTPM]":"56.0","Cell RNA - HEK 293 [nTPM]":"15.1","Cell RNA - HEL [nTPM]":"35.4","Cell RNA - HeLa [nTPM]":"45.8","Cell RNA - Hep G2 [nTPM]":"25.2","Cell RNA - HHSteC [nTPM]":"36.8","Cell RNA - HL-60 [nTPM]":"59.0","Cell RNA - HMC-1 [nTPM]":"17.8","Cell RNA - HSkMC [nTPM]":"39.6","Cell RNA - hTCEpi [nTPM]":"35.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"45.3","Cell RNA - hTERT-HME1 [nTPM]":"51.4","Cell RNA - hTERT-RPE1 [nTPM]":"39.1","Cell RNA - HUVEC TERT2 [nTPM]":"38.8","Cell RNA - JURKAT [nTPM]":"14.5","Cell RNA - K-562 [nTPM]":"14.4","Cell RNA - Karpas-707 [nTPM]":"61.1","Cell RNA - LHCN-M2 [nTPM]":"33.5","Cell RNA - MCF7 [nTPM]":"58.0","Cell RNA - MOLT-4 [nTPM]":"12.2","Cell RNA - NB-4 [nTPM]":"44.2","Cell RNA - NTERA-2 [nTPM]":"15.4","Cell RNA - OE19 [nTPM]":"55.7","Cell RNA - PC-3 [nTPM]":"20.7","Cell RNA - REH [nTPM]":"22.1","Cell RNA - RH-30 [nTPM]":"83.2","Cell RNA - RPMI-8226 [nTPM]":"26.5","Cell RNA - RPTEC TERT1 [nTPM]":"20.0","Cell RNA - RT4 [nTPM]":"38.3","Cell RNA - SCLC-21H [nTPM]":"71.5","Cell RNA - SH-SY5Y [nTPM]":"26.2","Cell RNA - SiHa [nTPM]":"43.1","Cell RNA - SK-BR-3 [nTPM]":"35.4","Cell RNA - SK-MEL-30 [nTPM]":"24.6","Cell RNA - SuSa [nTPM]":"12.5","Cell RNA - T-47d [nTPM]":"32.3","Cell RNA - THP-1 [nTPM]":"33.4","Cell RNA - TIME [nTPM]":"42.1","Cell RNA - U-138 MG [nTPM]":"48.7","Cell RNA - U-2 OS [nTPM]":"54.8","Cell RNA - U-2197 [nTPM]":"44.7","Cell RNA - U-251 MG [nTPM]":"34.7","Cell RNA - U-266\/70 [nTPM]":"28.5","Cell RNA - U-266\/84 [nTPM]":"31.5","Cell RNA - U-698 [nTPM]":"40.1","Cell RNA - U-87 MG [nTPM]":"26.6","Cell RNA - U-937 [nTPM]":"31.5","Cell RNA - WM-115 [nTPM]":"13.1","Blood RNA - basophil [nTPM]":"82.5","Blood RNA - classical monocyte [nTPM]":"31.0","Blood RNA - eosinophil [nTPM]":"73.5","Blood RNA - gdT-cell [nTPM]":"35.7","Blood RNA - intermediate monocyte [nTPM]":"33.1","Blood RNA - MAIT T-cell [nTPM]":"41.6","Blood RNA - memory B-cell [nTPM]":"74.1","Blood RNA - memory CD4 T-cell [nTPM]":"33.2","Blood RNA - memory CD8 T-cell [nTPM]":"34.8","Blood RNA - myeloid DC [nTPM]":"28.2","Blood RNA - naive B-cell [nTPM]":"62.8","Blood RNA - naive CD4 T-cell [nTPM]":"15.5","Blood RNA - naive CD8 T-cell [nTPM]":"31.0","Blood RNA - neutrophil [nTPM]":"123.7","Blood RNA - NK-cell [nTPM]":"65.1","Blood RNA - non-classical monocyte [nTPM]":"45.1","Blood RNA - plasmacytoid DC [nTPM]":"51.9","Blood RNA - T-reg [nTPM]":"25.3","Blood RNA - total PBMC [nTPM]":"21.1","Brain RNA - amygdala [nTPM]":"48.5","Brain RNA - basal ganglia [nTPM]":"144.1","Brain RNA - cerebellum [nTPM]":"63.2","Brain RNA - cerebral cortex [nTPM]":"125.6","Brain RNA - hippocampal formation [nTPM]":"97.4","Brain RNA - hypothalamus [nTPM]":"25.0","Brain RNA - medulla oblongata [nTPM]":"14.6","Brain RNA - midbrain [nTPM]":"11.0","Brain RNA - pons [nTPM]":"15.7","Brain RNA - spinal cord [nTPM]":"24.7","Brain RNA - thalamus [nTPM]":"23.9","Brain RNA - white matter [nTPM]":"54.3","Single Cell Type RNA - Adipocytes [nTPM]":"143.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"76.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"58.6","Single Cell Type RNA - Astrocytes [nTPM]":"284.1","Single Cell Type RNA - B-cells [nTPM]":"96.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"168.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"36.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"34.7","Single Cell Type RNA - Bipolar cells [nTPM]":"89.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"93.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"51.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"21.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"39.6","Single Cell Type RNA - dendritic cells [nTPM]":"81.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"60.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"21.3","Single Cell Type RNA - Early spermatids [nTPM]":"3.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"39.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"56.2","Single Cell Type RNA - Endothelial cells [nTPM]":"100.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"127.4","Single Cell Type RNA - Erythroid cells [nTPM]":"32.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"933.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"31.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"84.0","Single Cell Type RNA - Fibroblasts [nTPM]":"75.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"59.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"42.8","Single Cell Type RNA - granulocytes [nTPM]":"35.4","Single Cell Type RNA - Granulosa cells [nTPM]":"22.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"53.2","Single Cell Type RNA - Hepatocytes [nTPM]":"39.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"38.3","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"403.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"44.2","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"61.8","Single Cell Type RNA - Langerhans cells [nTPM]":"135.3","Single Cell Type RNA - Late spermatids [nTPM]":"8.4","Single Cell Type RNA - Leydig cells [nTPM]":"65.0","Single Cell Type RNA - Macrophages [nTPM]":"58.2","Single Cell Type RNA - Melanocytes [nTPM]":"92.5","Single Cell Type RNA - Microglial cells [nTPM]":"281.1","Single Cell Type RNA - monocytes [nTPM]":"64.3","Single Cell Type RNA - Muller glia cells [nTPM]":"21.2","Single Cell Type RNA - NK-cells [nTPM]":"56.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"348.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"139.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"53.3","Single Cell Type RNA - Paneth cells [nTPM]":"115.4","Single Cell Type RNA - Peritubular cells [nTPM]":"60.9","Single Cell Type RNA - Plasma cells [nTPM]":"63.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"127.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"51.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"25.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"82.9","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"66.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"67.5","Single Cell Type RNA - Spermatocytes [nTPM]":"12.7","Single Cell Type RNA - Spermatogonia [nTPM]":"26.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"27.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"172.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"27.5","Single Cell Type RNA - T-cells [nTPM]":"69.1","Single Cell Type RNA - Theca cells [nTPM]":"76.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"55.9","Single Cell Type RNA - Urothelial cells [nTPM]":"39.5"},{"Gene":"PPT1","Gene synonym":["CLN1","INCL","PPT"],"Ensembl":"ENSG00000131238","Gene description":"Palmitoyl-protein thioesterase 1","Uniprot":["P50897"],"Chromosome":"1","Position":"40072710-40097260","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Neurodegeneration","Neuronal ceroid lipofuscinosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"251.9","Kupffer cells":"315.8","Langerhans cells":"328.8","Macrophages":"271.3","monocytes":"227.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"1254.3","eosinophil":"624.2","intermediate monocyte":"1006.3","myeloid DC":"1091.1","neutrophil":"683.9","non-classical monocyte":"815.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"1091.1","granulocytes":"683.9","monocytes":"1254.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SK-BR-3":"1082.7","THP-1":"1449.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021546"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"240000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA021546":"AB_1855667"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.98e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Tissue RNA - adipose tissue [nTPM]":"69.8","Tissue RNA - adrenal gland [nTPM]":"59.4","Tissue RNA - amygdala [nTPM]":"92.9","Tissue RNA - appendix [nTPM]":"92.7","Tissue RNA - basal ganglia [nTPM]":"95.6","Tissue RNA - bone marrow [nTPM]":"117.5","Tissue RNA - breast [nTPM]":"95.7","Tissue RNA - cerebellum [nTPM]":"100.4","Tissue RNA - cerebral cortex [nTPM]":"135.9","Tissue RNA - cervix [nTPM]":"70.1","Tissue RNA - choroid plexus [nTPM]":"106.1","Tissue RNA - colon [nTPM]":"50.5","Tissue RNA - duodenum [nTPM]":"32.1","Tissue RNA - endometrium 1 [nTPM]":"72.7","Tissue RNA - epididymis [nTPM]":"60.1","Tissue RNA - esophagus [nTPM]":"45.1","Tissue RNA - fallopian tube [nTPM]":"55.4","Tissue RNA - gallbladder [nTPM]":"57.1","Tissue RNA - heart muscle [nTPM]":"45.3","Tissue RNA - hippocampal formation [nTPM]":"93.6","Tissue RNA - hypothalamus [nTPM]":"101.2","Tissue RNA - kidney [nTPM]":"75.8","Tissue RNA - liver [nTPM]":"54.1","Tissue RNA - lung [nTPM]":"128.5","Tissue RNA - lymph node [nTPM]":"93.9","Tissue RNA - medulla oblongata [nTPM]":"97.0","Tissue RNA - midbrain [nTPM]":"96.7","Tissue RNA - ovary [nTPM]":"68.6","Tissue RNA - pancreas [nTPM]":"42.6","Tissue RNA - parathyroid gland [nTPM]":"79.2","Tissue RNA - pituitary gland [nTPM]":"39.0","Tissue RNA - placenta [nTPM]":"74.8","Tissue RNA - pons [nTPM]":"99.6","Tissue RNA - prostate [nTPM]":"73.4","Tissue RNA - rectum [nTPM]":"58.8","Tissue RNA - retina [nTPM]":"89.4","Tissue RNA - salivary gland [nTPM]":"56.8","Tissue RNA - seminal vesicle [nTPM]":"63.2","Tissue RNA - skeletal muscle [nTPM]":"21.3","Tissue RNA - skin 1 [nTPM]":"40.3","Tissue RNA - small intestine [nTPM]":"39.2","Tissue RNA - smooth muscle [nTPM]":"95.3","Tissue RNA - spinal cord [nTPM]":"101.6","Tissue RNA - spleen [nTPM]":"177.0","Tissue RNA - stomach 1 [nTPM]":"45.1","Tissue RNA - testis [nTPM]":"37.6","Tissue RNA - thalamus [nTPM]":"99.1","Tissue RNA - thymus [nTPM]":"78.0","Tissue RNA - thyroid gland [nTPM]":"60.0","Tissue RNA - tongue [nTPM]":"37.1","Tissue RNA - tonsil [nTPM]":"75.1","Tissue RNA - urinary bladder [nTPM]":"79.1","Tissue RNA - vagina [nTPM]":"34.7","Tissue RNA - white matter [nTPM]":"113.5","Cell RNA - A-431 [nTPM]":"115.6","Cell RNA - A549 [nTPM]":"62.5","Cell RNA - AF22 [nTPM]":"93.7","Cell RNA - AN3-CA [nTPM]":"81.0","Cell RNA - ASC diff [nTPM]":"106.5","Cell RNA - ASC TERT1 [nTPM]":"92.1","Cell RNA - BEWO [nTPM]":"209.8","Cell RNA - BJ [nTPM]":"68.4","Cell RNA - BJ hTERT+ [nTPM]":"127.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"153.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"183.3","Cell RNA - CACO-2 [nTPM]":"350.1","Cell RNA - CAPAN-2 [nTPM]":"270.5","Cell RNA - Daudi [nTPM]":"140.1","Cell RNA - EFO-21 [nTPM]":"118.1","Cell RNA - fHDF\/TERT166 [nTPM]":"65.2","Cell RNA - GAMG [nTPM]":"112.2","Cell RNA - HaCaT [nTPM]":"209.5","Cell RNA - HAP1 [nTPM]":"154.9","Cell RNA - HBEC3-KT [nTPM]":"112.7","Cell RNA - HBF TERT88 [nTPM]":"163.6","Cell RNA - HDLM-2 [nTPM]":"186.4","Cell RNA - HEK 293 [nTPM]":"151.4","Cell RNA - HEL [nTPM]":"100.3","Cell RNA - HeLa [nTPM]":"127.2","Cell RNA - Hep G2 [nTPM]":"155.5","Cell RNA - HHSteC [nTPM]":"137.5","Cell RNA - HL-60 [nTPM]":"233.7","Cell RNA - HMC-1 [nTPM]":"158.9","Cell RNA - HSkMC [nTPM]":"103.1","Cell RNA - hTCEpi [nTPM]":"107.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"108.7","Cell RNA - hTERT-HME1 [nTPM]":"126.4","Cell RNA - hTERT-RPE1 [nTPM]":"79.7","Cell RNA - HUVEC TERT2 [nTPM]":"190.9","Cell RNA - JURKAT [nTPM]":"108.8","Cell RNA - K-562 [nTPM]":"167.7","Cell RNA - Karpas-707 [nTPM]":"247.0","Cell RNA - LHCN-M2 [nTPM]":"80.6","Cell RNA - MCF7 [nTPM]":"168.1","Cell RNA - MOLT-4 [nTPM]":"109.8","Cell RNA - NB-4 [nTPM]":"88.3","Cell RNA - NTERA-2 [nTPM]":"258.3","Cell RNA - OE19 [nTPM]":"163.9","Cell RNA - PC-3 [nTPM]":"93.8","Cell RNA - REH [nTPM]":"116.0","Cell RNA - RH-30 [nTPM]":"263.7","Cell RNA - RPMI-8226 [nTPM]":"226.1","Cell RNA - RPTEC TERT1 [nTPM]":"89.2","Cell RNA - RT4 [nTPM]":"152.0","Cell RNA - SCLC-21H [nTPM]":"114.1","Cell RNA - SH-SY5Y [nTPM]":"96.9","Cell RNA - SiHa [nTPM]":"247.9","Cell RNA - SK-BR-3 [nTPM]":"1082.7","Cell RNA - SK-MEL-30 [nTPM]":"298.6","Cell RNA - SuSa [nTPM]":"111.7","Cell RNA - T-47d [nTPM]":"199.3","Cell RNA - THP-1 [nTPM]":"1449.6","Cell RNA - TIME [nTPM]":"85.2","Cell RNA - U-138 MG [nTPM]":"100.7","Cell RNA - U-2 OS [nTPM]":"147.1","Cell RNA - U-2197 [nTPM]":"70.7","Cell RNA - U-251 MG [nTPM]":"174.9","Cell RNA - U-266\/70 [nTPM]":"161.2","Cell RNA - U-266\/84 [nTPM]":"383.8","Cell RNA - U-698 [nTPM]":"133.9","Cell RNA - U-87 MG [nTPM]":"109.4","Cell RNA - U-937 [nTPM]":"408.7","Cell RNA - WM-115 [nTPM]":"155.5","Blood RNA - basophil [nTPM]":"85.7","Blood RNA - classical monocyte [nTPM]":"1254.3","Blood RNA - eosinophil [nTPM]":"624.2","Blood RNA - gdT-cell [nTPM]":"122.2","Blood RNA - intermediate monocyte [nTPM]":"1006.3","Blood RNA - MAIT T-cell [nTPM]":"137.9","Blood RNA - memory B-cell [nTPM]":"118.8","Blood RNA - memory CD4 T-cell [nTPM]":"171.5","Blood RNA - memory CD8 T-cell [nTPM]":"131.3","Blood RNA - myeloid DC [nTPM]":"1091.1","Blood RNA - naive B-cell [nTPM]":"118.6","Blood RNA - naive CD4 T-cell [nTPM]":"227.0","Blood RNA - naive CD8 T-cell [nTPM]":"168.3","Blood RNA - neutrophil [nTPM]":"683.9","Blood RNA - NK-cell [nTPM]":"100.3","Blood RNA - non-classical monocyte [nTPM]":"815.7","Blood RNA - plasmacytoid DC [nTPM]":"101.8","Blood RNA - T-reg [nTPM]":"204.1","Blood RNA - total PBMC [nTPM]":"1586.9","Brain RNA - amygdala [nTPM]":"92.9","Brain RNA - basal ganglia [nTPM]":"95.6","Brain RNA - cerebellum [nTPM]":"100.4","Brain RNA - cerebral cortex [nTPM]":"135.9","Brain RNA - hippocampal formation [nTPM]":"93.6","Brain RNA - hypothalamus [nTPM]":"101.2","Brain RNA - medulla oblongata [nTPM]":"97.0","Brain RNA - midbrain [nTPM]":"96.7","Brain RNA - pons [nTPM]":"99.6","Brain RNA - spinal cord [nTPM]":"101.6","Brain RNA - thalamus [nTPM]":"99.1","Brain RNA - white matter [nTPM]":"113.5","Single Cell Type RNA - Adipocytes [nTPM]":"45.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"47.7","Single Cell Type RNA - Astrocytes [nTPM]":"19.9","Single Cell Type RNA - B-cells [nTPM]":"33.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"39.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"77.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"34.7","Single Cell Type RNA - Bipolar cells [nTPM]":"46.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"55.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"37.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"41.5","Single Cell Type RNA - Club cells [nTPM]":"40.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"51.7","Single Cell Type RNA - dendritic cells [nTPM]":"28.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"59.0","Single Cell Type RNA - Early spermatids [nTPM]":"64.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"46.4","Single Cell Type RNA - Endothelial cells [nTPM]":"49.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.9","Single Cell Type RNA - Erythroid cells [nTPM]":"40.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"28.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"42.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"66.5","Single Cell Type RNA - Fibroblasts [nTPM]":"56.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.2","Single Cell Type RNA - granulocytes [nTPM]":"84.9","Single Cell Type RNA - Granulosa cells [nTPM]":"34.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"47.5","Single Cell Type RNA - Hepatocytes [nTPM]":"9.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"251.9","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"39.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.1","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"315.8","Single Cell Type RNA - Langerhans cells [nTPM]":"328.8","Single Cell Type RNA - Late spermatids [nTPM]":"87.6","Single Cell Type RNA - Leydig cells [nTPM]":"31.4","Single Cell Type RNA - Macrophages [nTPM]":"271.3","Single Cell Type RNA - Melanocytes [nTPM]":"67.6","Single Cell Type RNA - Microglial cells [nTPM]":"31.9","Single Cell Type RNA - monocytes [nTPM]":"227.2","Single Cell Type RNA - Muller glia cells [nTPM]":"120.3","Single Cell Type RNA - NK-cells [nTPM]":"28.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"27.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"22.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.2","Single Cell Type RNA - Paneth cells [nTPM]":"6.0","Single Cell Type RNA - Peritubular cells [nTPM]":"39.5","Single Cell Type RNA - Plasma cells [nTPM]":"34.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"42.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"32.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"37.0","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"49.3","Single Cell Type RNA - Spermatocytes [nTPM]":"17.5","Single Cell Type RNA - Spermatogonia [nTPM]":"33.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"41.2","Single Cell Type RNA - T-cells [nTPM]":"43.5","Single Cell Type RNA - Theca cells [nTPM]":"39.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.4","Single Cell Type RNA - Urothelial cells [nTPM]":"35.6"},{"Gene":"PRDM16","Gene synonym":["KIAA1675","KMT8F","MEL1","MGC166915","PFM13"],"Ensembl":"ENSG00000142611","Gene description":"PR\/SET domain 16","Uniprot":["Q9HAZ2"],"Chromosome":"1","Position":"3069168-3438621","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transcription factors"],"Biological process":["Differentiation","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Methyltransferase","Repressor","Transferase"],"Disease involvement":["Cancer-related genes","Cardiomyopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"16.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"173.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"16","RNA blood cell specific nTPM":{"NK-cell":"2.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"16","RNA blood lineage specific nTPM":{"NK-cells":"2.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEK 293":"1.8","HHSteC":"2.0","hTERT-RPE1":"6.7","MCF7":"1.6","OE19":"3.5"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"basal ganglia":"15.7"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050343","HPA060467"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA050343":"AB_2681099","HPA060467":"AB_2684287"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.70e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.6","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"3.7","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"4.8","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.1","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"4.1","Tissue RNA - cervix [nTPM]":"1.3","Tissue RNA - choroid plexus [nTPM]":"16.2","Tissue RNA - colon [nTPM]":"1.1","Tissue RNA - duodenum [nTPM]":"7.4","Tissue RNA - endometrium 1 [nTPM]":"1.0","Tissue RNA - epididymis [nTPM]":"2.1","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"1.4","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"5.4","Tissue RNA - hippocampal formation [nTPM]":"2.8","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"6.8","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"2.5","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"1.7","Tissue RNA - ovary [nTPM]":"1.5","Tissue RNA - pancreas [nTPM]":"5.8","Tissue RNA - parathyroid gland [nTPM]":"0.9","Tissue RNA - pituitary gland [nTPM]":"0.6","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"0.7","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"2.2","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"2.6","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"2.1","Tissue RNA - stomach 1 [nTPM]":"9.3","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"4.1","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"8.0","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"0.9","Tissue RNA - vagina [nTPM]":"1.1","Tissue RNA - white matter [nTPM]":"1.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"1.5","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"1.4","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"1.3","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"1.8","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"2.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.7","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"6.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.6","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"3.5","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.5","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.8","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"2.4","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.7","Brain RNA - basal ganglia [nTPM]":"4.8","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"4.1","Brain RNA - hippocampal formation [nTPM]":"2.8","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"1.7","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"4.1","Brain RNA - white matter [nTPM]":"1.5","Single Cell Type RNA - Adipocytes [nTPM]":"4.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.5","Single Cell Type RNA - Astrocytes [nTPM]":"173.7","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"6.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"10.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"2.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.2","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"30.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.8","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"PRDM6","Gene synonym":["KMT8C","PRISM"],"Ensembl":"ENSG00000061455","Gene description":"PR\/SET domain 6","Uniprot":["Q9NQX0"],"Chromosome":"5","Position":"123089241-123194266","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","Methyltransferase","Repressor","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"4.9","urinary bladder":"9.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"15.0","Endometrial stromal cells":"6.5","Excitatory neurons":"7.9","Fibroblasts":"10.7","Late spermatids":"7.1","Oligodendrocytes":"11.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"3.6","HEK 293":"5.2","HEL":"1.1"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"2.3"},"Antibody":["HPA030324"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA030324":"AB_10670032"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.30e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.7","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.6","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"0.9","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"4.9","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.7","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.6","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"3.3","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"2.9","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"1.9","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"4.2","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"1.3","Tissue RNA - rectum [nTPM]":"1.0","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.6","Tissue RNA - smooth muscle [nTPM]":"0.7","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.6","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.8","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"9.0","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.3","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"3.6","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.7","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"5.2","Cell RNA - HEL [nTPM]":"1.1","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"1.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.5","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.6","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.8","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"15.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"3.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.5","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"10.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"3.5","Single Cell Type RNA - Late spermatids [nTPM]":"7.1","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"0.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.2","Single Cell Type RNA - Spermatocytes [nTPM]":"2.3","Single Cell Type RNA - Spermatogonia [nTPM]":"4.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"6.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"PREPL","Gene synonym":["KIAA0436"],"Ensembl":"ENSG00000138078","Gene description":"Prolyl endopeptidase like","Uniprot":["Q4J6C6"],"Chromosome":"2","Position":"44316281-44361862","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"243.1","Inhibitory neurons":"219.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063238"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA063238":"AB_2684967"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Tissue RNA - adipose tissue [nTPM]":"26.2","Tissue RNA - adrenal gland [nTPM]":"50.9","Tissue RNA - amygdala [nTPM]":"64.6","Tissue RNA - appendix [nTPM]":"18.4","Tissue RNA - basal ganglia [nTPM]":"67.4","Tissue RNA - bone marrow [nTPM]":"5.5","Tissue RNA - breast [nTPM]":"31.9","Tissue RNA - cerebellum [nTPM]":"42.9","Tissue RNA - cerebral cortex [nTPM]":"133.1","Tissue RNA - cervix [nTPM]":"35.9","Tissue RNA - choroid plexus [nTPM]":"27.5","Tissue RNA - colon [nTPM]":"24.4","Tissue RNA - duodenum [nTPM]":"26.1","Tissue RNA - endometrium 1 [nTPM]":"47.2","Tissue RNA - epididymis [nTPM]":"70.9","Tissue RNA - esophagus [nTPM]":"22.9","Tissue RNA - fallopian tube [nTPM]":"33.6","Tissue RNA - gallbladder [nTPM]":"28.4","Tissue RNA - heart muscle [nTPM]":"62.7","Tissue RNA - hippocampal formation [nTPM]":"73.1","Tissue RNA - hypothalamus [nTPM]":"93.1","Tissue RNA - kidney [nTPM]":"62.5","Tissue RNA - liver [nTPM]":"21.6","Tissue RNA - lung [nTPM]":"24.5","Tissue RNA - lymph node [nTPM]":"17.4","Tissue RNA - medulla oblongata [nTPM]":"45.3","Tissue RNA - midbrain [nTPM]":"26.0","Tissue RNA - ovary [nTPM]":"49.8","Tissue RNA - pancreas [nTPM]":"25.2","Tissue RNA - parathyroid gland [nTPM]":"54.4","Tissue RNA - pituitary gland [nTPM]":"52.5","Tissue RNA - placenta [nTPM]":"21.4","Tissue RNA - pons [nTPM]":"41.7","Tissue RNA - prostate [nTPM]":"37.3","Tissue RNA - rectum [nTPM]":"29.4","Tissue RNA - retina [nTPM]":"123.8","Tissue RNA - salivary gland [nTPM]":"26.2","Tissue RNA - seminal vesicle [nTPM]":"33.1","Tissue RNA - skeletal muscle [nTPM]":"34.3","Tissue RNA - skin 1 [nTPM]":"22.3","Tissue RNA - small intestine [nTPM]":"27.9","Tissue RNA - smooth muscle [nTPM]":"34.1","Tissue RNA - spinal cord [nTPM]":"34.0","Tissue RNA - spleen [nTPM]":"23.1","Tissue RNA - stomach 1 [nTPM]":"26.4","Tissue RNA - testis [nTPM]":"28.2","Tissue RNA - thalamus [nTPM]":"53.4","Tissue RNA - thymus [nTPM]":"19.1","Tissue RNA - thyroid gland [nTPM]":"61.3","Tissue RNA - tongue [nTPM]":"51.3","Tissue RNA - tonsil [nTPM]":"17.9","Tissue RNA - urinary bladder [nTPM]":"23.6","Tissue RNA - vagina [nTPM]":"23.9","Tissue RNA - white matter [nTPM]":"58.4","Cell RNA - A-431 [nTPM]":"41.2","Cell RNA - A549 [nTPM]":"31.7","Cell RNA - AF22 [nTPM]":"35.3","Cell RNA - AN3-CA [nTPM]":"45.3","Cell RNA - ASC diff [nTPM]":"55.7","Cell RNA - ASC TERT1 [nTPM]":"58.0","Cell RNA - BEWO [nTPM]":"26.8","Cell RNA - BJ [nTPM]":"45.1","Cell RNA - BJ hTERT+ [nTPM]":"34.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"32.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"27.4","Cell RNA - CACO-2 [nTPM]":"34.1","Cell RNA - CAPAN-2 [nTPM]":"28.4","Cell RNA - Daudi [nTPM]":"52.3","Cell RNA - EFO-21 [nTPM]":"61.2","Cell RNA - fHDF\/TERT166 [nTPM]":"47.5","Cell RNA - GAMG [nTPM]":"36.6","Cell RNA - HaCaT [nTPM]":"34.6","Cell RNA - HAP1 [nTPM]":"50.6","Cell RNA - HBEC3-KT [nTPM]":"33.0","Cell RNA - HBF TERT88 [nTPM]":"61.0","Cell RNA - HDLM-2 [nTPM]":"48.7","Cell RNA - HEK 293 [nTPM]":"36.2","Cell RNA - HEL [nTPM]":"35.5","Cell RNA - HeLa [nTPM]":"24.2","Cell RNA - Hep G2 [nTPM]":"26.3","Cell RNA - HHSteC [nTPM]":"40.0","Cell RNA - HL-60 [nTPM]":"35.8","Cell RNA - HMC-1 [nTPM]":"32.5","Cell RNA - HSkMC [nTPM]":"37.9","Cell RNA - hTCEpi [nTPM]":"64.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"61.8","Cell RNA - hTERT-HME1 [nTPM]":"50.1","Cell RNA - hTERT-RPE1 [nTPM]":"62.9","Cell RNA - HUVEC TERT2 [nTPM]":"31.4","Cell RNA - JURKAT [nTPM]":"24.3","Cell RNA - K-562 [nTPM]":"45.6","Cell RNA - Karpas-707 [nTPM]":"72.6","Cell RNA - LHCN-M2 [nTPM]":"43.6","Cell RNA - MCF7 [nTPM]":"22.2","Cell RNA - MOLT-4 [nTPM]":"39.1","Cell RNA - NB-4 [nTPM]":"17.4","Cell RNA - NTERA-2 [nTPM]":"33.4","Cell RNA - OE19 [nTPM]":"52.8","Cell RNA - PC-3 [nTPM]":"35.1","Cell RNA - REH [nTPM]":"30.1","Cell RNA - RH-30 [nTPM]":"42.8","Cell RNA - RPMI-8226 [nTPM]":"38.0","Cell RNA - RPTEC TERT1 [nTPM]":"61.4","Cell RNA - RT4 [nTPM]":"24.0","Cell RNA - SCLC-21H [nTPM]":"58.3","Cell RNA - SH-SY5Y [nTPM]":"46.5","Cell RNA - SiHa [nTPM]":"28.9","Cell RNA - SK-BR-3 [nTPM]":"30.6","Cell RNA - SK-MEL-30 [nTPM]":"67.4","Cell RNA - SuSa [nTPM]":"33.9","Cell RNA - T-47d [nTPM]":"41.4","Cell RNA - THP-1 [nTPM]":"27.6","Cell RNA - TIME [nTPM]":"32.8","Cell RNA - U-138 MG [nTPM]":"56.3","Cell RNA - U-2 OS [nTPM]":"32.1","Cell RNA - U-2197 [nTPM]":"44.6","Cell RNA - U-251 MG [nTPM]":"31.0","Cell RNA - U-266\/70 [nTPM]":"40.2","Cell RNA - U-266\/84 [nTPM]":"28.2","Cell RNA - U-698 [nTPM]":"34.3","Cell RNA - U-87 MG [nTPM]":"65.9","Cell RNA - U-937 [nTPM]":"40.1","Cell RNA - WM-115 [nTPM]":"42.5","Blood RNA - basophil [nTPM]":"6.9","Blood RNA - classical monocyte [nTPM]":"4.4","Blood RNA - eosinophil [nTPM]":"3.5","Blood RNA - gdT-cell [nTPM]":"7.9","Blood RNA - intermediate monocyte [nTPM]":"4.9","Blood RNA - MAIT T-cell [nTPM]":"11.2","Blood RNA - memory B-cell [nTPM]":"8.5","Blood RNA - memory CD4 T-cell [nTPM]":"7.3","Blood RNA - memory CD8 T-cell [nTPM]":"8.5","Blood RNA - myeloid DC [nTPM]":"6.3","Blood RNA - naive B-cell [nTPM]":"7.0","Blood RNA - naive CD4 T-cell [nTPM]":"10.7","Blood RNA - naive CD8 T-cell [nTPM]":"8.7","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"11.1","Blood RNA - non-classical monocyte [nTPM]":"4.3","Blood RNA - plasmacytoid DC [nTPM]":"2.9","Blood RNA - T-reg [nTPM]":"8.8","Blood RNA - total PBMC [nTPM]":"5.8","Brain RNA - amygdala [nTPM]":"64.6","Brain RNA - basal ganglia [nTPM]":"67.4","Brain RNA - cerebellum [nTPM]":"42.9","Brain RNA - cerebral cortex [nTPM]":"133.1","Brain RNA - hippocampal formation [nTPM]":"73.1","Brain RNA - hypothalamus [nTPM]":"93.1","Brain RNA - medulla oblongata [nTPM]":"45.3","Brain RNA - midbrain [nTPM]":"26.0","Brain RNA - pons [nTPM]":"41.7","Brain RNA - spinal cord [nTPM]":"34.0","Brain RNA - thalamus [nTPM]":"53.4","Brain RNA - white matter [nTPM]":"58.4","Single Cell Type RNA - Adipocytes [nTPM]":"16.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"37.4","Single Cell Type RNA - Astrocytes [nTPM]":"83.2","Single Cell Type RNA - B-cells [nTPM]":"34.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.6","Single Cell Type RNA - Bipolar cells [nTPM]":"89.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"33.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"26.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"88.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"21.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"64.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"47.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.7","Single Cell Type RNA - dendritic cells [nTPM]":"30.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"20.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"39.2","Single Cell Type RNA - Ductal cells [nTPM]":"17.4","Single Cell Type RNA - Early spermatids [nTPM]":"21.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"40.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"36.7","Single Cell Type RNA - Endothelial cells [nTPM]":"18.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"33.0","Single Cell Type RNA - Erythroid cells [nTPM]":"13.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"243.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.9","Single Cell Type RNA - Fibroblasts [nTPM]":"29.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"28.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"32.1","Single Cell Type RNA - granulocytes [nTPM]":"13.3","Single Cell Type RNA - Granulosa cells [nTPM]":"21.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.8","Single Cell Type RNA - Hepatocytes [nTPM]":"32.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.6","Single Cell Type RNA - Horizontal cells [nTPM]":"144.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"219.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.2","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"13.5","Single Cell Type RNA - Langerhans cells [nTPM]":"7.5","Single Cell Type RNA - Late spermatids [nTPM]":"10.0","Single Cell Type RNA - Leydig cells [nTPM]":"35.4","Single Cell Type RNA - Macrophages [nTPM]":"14.2","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"55.3","Single Cell Type RNA - monocytes [nTPM]":"12.8","Single Cell Type RNA - Muller glia cells [nTPM]":"41.4","Single Cell Type RNA - NK-cells [nTPM]":"32.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"81.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"126.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.6","Single Cell Type RNA - Paneth cells [nTPM]":"20.8","Single Cell Type RNA - Peritubular cells [nTPM]":"33.1","Single Cell Type RNA - Plasma cells [nTPM]":"21.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"38.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"35.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"63.2","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"44.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.2","Single Cell Type RNA - Spermatocytes [nTPM]":"29.2","Single Cell Type RNA - Spermatogonia [nTPM]":"28.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.8","Single Cell Type RNA - T-cells [nTPM]":"29.1","Single Cell Type RNA - Theca cells [nTPM]":"26.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.1","Single Cell Type RNA - Urothelial cells [nTPM]":"10.7"},{"Gene":"PRF1","Gene synonym":["HPLH2","P1","PFP"],"Ensembl":"ENSG00000180644","Gene description":"Perforin 1","Uniprot":["P14222"],"Chromosome":"10","Position":"70597348-70602759","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Cytolysis"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Familial hemophagocytic lymphohistiocytosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"bone marrow":"28.6","lung":"16.5","lymphoid tissue":"49.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"542.1","NK-cells":"1231.7","T-cells":"265.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"gdT-cell":"900.4","MAIT T-cell":"628.8","memory CD8 T-cell":"499.1","naive CD8 T-cell":"313.0","NK-cell":"656.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"50","RNA blood lineage specific nTPM":{"NK-cells":"656.8","T-cells":"900.4"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"HDLM-2":"240.1"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002436","HPA037940"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2100000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB002436":"AB_563955","HPA037940":"AB_2675747"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.09e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.54e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.08e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-3"},"Tissue RNA - adipose tissue [nTPM]":"5.0","Tissue RNA - adrenal gland [nTPM]":"2.0","Tissue RNA - amygdala [nTPM]":"0.7","Tissue RNA - appendix [nTPM]":"7.6","Tissue RNA - basal ganglia [nTPM]":"0.7","Tissue RNA - bone marrow [nTPM]":"28.6","Tissue RNA - breast [nTPM]":"2.7","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"1.3","Tissue RNA - cervix [nTPM]":"1.3","Tissue RNA - choroid plexus [nTPM]":"1.3","Tissue RNA - colon [nTPM]":"2.2","Tissue RNA - duodenum [nTPM]":"2.3","Tissue RNA - endometrium 1 [nTPM]":"3.5","Tissue RNA - epididymis [nTPM]":"1.1","Tissue RNA - esophagus [nTPM]":"1.9","Tissue RNA - fallopian tube [nTPM]":"1.9","Tissue RNA - gallbladder [nTPM]":"4.2","Tissue RNA - heart muscle [nTPM]":"2.2","Tissue RNA - hippocampal formation [nTPM]":"0.6","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"1.7","Tissue RNA - liver [nTPM]":"6.3","Tissue RNA - lung [nTPM]":"16.5","Tissue RNA - lymph node [nTPM]":"20.3","Tissue RNA - medulla oblongata [nTPM]":"1.4","Tissue RNA - midbrain [nTPM]":"0.7","Tissue RNA - ovary [nTPM]":"1.0","Tissue RNA - pancreas [nTPM]":"1.0","Tissue RNA - parathyroid gland [nTPM]":"0.5","Tissue RNA - pituitary gland [nTPM]":"0.9","Tissue RNA - placenta [nTPM]":"2.7","Tissue RNA - pons [nTPM]":"1.0","Tissue RNA - prostate [nTPM]":"1.5","Tissue RNA - rectum [nTPM]":"1.4","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"2.3","Tissue RNA - seminal vesicle [nTPM]":"1.2","Tissue RNA - skeletal muscle [nTPM]":"2.6","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"5.2","Tissue RNA - smooth muscle [nTPM]":"2.0","Tissue RNA - spinal cord [nTPM]":"1.3","Tissue RNA - spleen [nTPM]":"49.4","Tissue RNA - stomach 1 [nTPM]":"4.7","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"5.8","Tissue RNA - thyroid gland [nTPM]":"2.6","Tissue RNA - tongue [nTPM]":"1.5","Tissue RNA - tonsil [nTPM]":"4.9","Tissue RNA - urinary bladder [nTPM]":"3.8","Tissue RNA - vagina [nTPM]":"1.9","Tissue RNA - white matter [nTPM]":"1.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.7","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"240.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"1.4","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"7.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"11.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"22.2","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"2.2","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"5.2","Blood RNA - classical monocyte [nTPM]":"1.9","Blood RNA - eosinophil [nTPM]":"0.9","Blood RNA - gdT-cell [nTPM]":"900.4","Blood RNA - intermediate monocyte [nTPM]":"1.7","Blood RNA - MAIT T-cell [nTPM]":"628.8","Blood RNA - memory B-cell [nTPM]":"4.0","Blood RNA - memory CD4 T-cell [nTPM]":"125.8","Blood RNA - memory CD8 T-cell [nTPM]":"499.1","Blood RNA - myeloid DC [nTPM]":"2.0","Blood RNA - naive B-cell [nTPM]":"3.5","Blood RNA - naive CD4 T-cell [nTPM]":"52.1","Blood RNA - naive CD8 T-cell [nTPM]":"313.0","Blood RNA - neutrophil [nTPM]":"15.4","Blood RNA - NK-cell [nTPM]":"656.8","Blood RNA - non-classical monocyte [nTPM]":"2.6","Blood RNA - plasmacytoid DC [nTPM]":"2.9","Blood RNA - T-reg [nTPM]":"108.8","Blood RNA - total PBMC [nTPM]":"587.5","Brain RNA - amygdala [nTPM]":"0.7","Brain RNA - basal ganglia [nTPM]":"0.7","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"1.3","Brain RNA - hippocampal formation [nTPM]":"0.6","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"1.4","Brain RNA - midbrain [nTPM]":"0.7","Brain RNA - pons [nTPM]":"1.0","Brain RNA - spinal cord [nTPM]":"1.3","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"1.0","Single Cell Type RNA - Adipocytes [nTPM]":"3.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"4.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"2.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"542.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"1.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"19.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"2.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.8","Single Cell Type RNA - Hepatocytes [nTPM]":"2.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"7.8","Single Cell Type RNA - Langerhans cells [nTPM]":"2.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"5.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"7.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"1231.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"88.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"265.4","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PRKACA","Gene synonym":["PKACa"],"Ensembl":"ENSG00000072062","Gene description":"Protein kinase cAMP-activated catalytic subunit alpha","Uniprot":["P17612"],"Chromosome":"19","Position":"14091688-14118084","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Cushing syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"310.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"116.8","Theca cells":"100.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010361","HPA071185"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytokinetic bridge","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":["Cytokinetic bridge"],"Antibody RRID":{"CAB010361":"AB_2268772","HPA071185":"AB_2686356"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.28e-6"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.26e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.36e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.47e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-3"},"Tissue RNA - adipose tissue [nTPM]":"62.7","Tissue RNA - adrenal gland [nTPM]":"126.5","Tissue RNA - amygdala [nTPM]":"46.6","Tissue RNA - appendix [nTPM]":"27.6","Tissue RNA - basal ganglia [nTPM]":"47.6","Tissue RNA - bone marrow [nTPM]":"18.9","Tissue RNA - breast [nTPM]":"53.9","Tissue RNA - cerebellum [nTPM]":"39.9","Tissue RNA - cerebral cortex [nTPM]":"64.2","Tissue RNA - cervix [nTPM]":"53.2","Tissue RNA - choroid plexus [nTPM]":"29.5","Tissue RNA - colon [nTPM]":"59.0","Tissue RNA - duodenum [nTPM]":"20.9","Tissue RNA - endometrium 1 [nTPM]":"56.9","Tissue RNA - epididymis [nTPM]":"28.5","Tissue RNA - esophagus [nTPM]":"41.8","Tissue RNA - fallopian tube [nTPM]":"53.7","Tissue RNA - gallbladder [nTPM]":"14.2","Tissue RNA - heart muscle [nTPM]":"204.8","Tissue RNA - hippocampal formation [nTPM]":"49.2","Tissue RNA - hypothalamus [nTPM]":"53.3","Tissue RNA - kidney [nTPM]":"35.4","Tissue RNA - liver [nTPM]":"78.4","Tissue RNA - lung [nTPM]":"46.1","Tissue RNA - lymph node [nTPM]":"15.9","Tissue RNA - medulla oblongata [nTPM]":"56.8","Tissue RNA - midbrain [nTPM]":"54.5","Tissue RNA - ovary [nTPM]":"94.1","Tissue RNA - pancreas [nTPM]":"34.0","Tissue RNA - parathyroid gland [nTPM]":"21.6","Tissue RNA - pituitary gland [nTPM]":"71.2","Tissue RNA - placenta [nTPM]":"17.3","Tissue RNA - pons [nTPM]":"55.3","Tissue RNA - prostate [nTPM]":"41.2","Tissue RNA - rectum [nTPM]":"13.0","Tissue RNA - retina [nTPM]":"25.2","Tissue RNA - salivary gland [nTPM]":"42.3","Tissue RNA - seminal vesicle [nTPM]":"20.8","Tissue RNA - skeletal muscle [nTPM]":"310.9","Tissue RNA - skin 1 [nTPM]":"42.3","Tissue RNA - small intestine [nTPM]":"36.3","Tissue RNA - smooth muscle [nTPM]":"21.8","Tissue RNA - spinal cord [nTPM]":"40.7","Tissue RNA - spleen [nTPM]":"71.6","Tissue RNA - stomach 1 [nTPM]":"40.2","Tissue RNA - testis [nTPM]":"57.2","Tissue RNA - thalamus [nTPM]":"50.3","Tissue RNA - thymus [nTPM]":"18.2","Tissue RNA - thyroid gland [nTPM]":"39.6","Tissue RNA - tongue [nTPM]":"122.1","Tissue RNA - tonsil [nTPM]":"13.4","Tissue RNA - urinary bladder [nTPM]":"50.6","Tissue RNA - vagina [nTPM]":"44.2","Tissue RNA - white matter [nTPM]":"46.6","Cell RNA - A-431 [nTPM]":"37.5","Cell RNA - A549 [nTPM]":"16.3","Cell RNA - AF22 [nTPM]":"40.3","Cell RNA - AN3-CA [nTPM]":"74.4","Cell RNA - ASC diff [nTPM]":"36.2","Cell RNA - ASC TERT1 [nTPM]":"30.8","Cell RNA - BEWO [nTPM]":"9.9","Cell RNA - BJ [nTPM]":"30.5","Cell RNA - BJ hTERT+ [nTPM]":"23.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"32.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"27.5","Cell RNA - CACO-2 [nTPM]":"21.6","Cell RNA - CAPAN-2 [nTPM]":"15.0","Cell RNA - Daudi [nTPM]":"13.8","Cell RNA - EFO-21 [nTPM]":"26.2","Cell RNA - fHDF\/TERT166 [nTPM]":"49.2","Cell RNA - GAMG [nTPM]":"22.9","Cell RNA - HaCaT [nTPM]":"25.4","Cell RNA - HAP1 [nTPM]":"26.7","Cell RNA - HBEC3-KT [nTPM]":"26.6","Cell RNA - HBF TERT88 [nTPM]":"32.3","Cell RNA - HDLM-2 [nTPM]":"23.1","Cell RNA - HEK 293 [nTPM]":"17.7","Cell RNA - HEL [nTPM]":"27.7","Cell RNA - HeLa [nTPM]":"20.6","Cell RNA - Hep G2 [nTPM]":"24.4","Cell RNA - HHSteC [nTPM]":"36.8","Cell RNA - HL-60 [nTPM]":"21.9","Cell RNA - HMC-1 [nTPM]":"33.5","Cell RNA - HSkMC [nTPM]":"33.8","Cell RNA - hTCEpi [nTPM]":"18.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"30.0","Cell RNA - hTERT-HME1 [nTPM]":"11.1","Cell RNA - hTERT-RPE1 [nTPM]":"26.6","Cell RNA - HUVEC TERT2 [nTPM]":"29.7","Cell RNA - JURKAT [nTPM]":"19.0","Cell RNA - K-562 [nTPM]":"29.1","Cell RNA - Karpas-707 [nTPM]":"47.3","Cell RNA - LHCN-M2 [nTPM]":"36.7","Cell RNA - MCF7 [nTPM]":"48.1","Cell RNA - MOLT-4 [nTPM]":"46.3","Cell RNA - NB-4 [nTPM]":"31.9","Cell RNA - NTERA-2 [nTPM]":"21.5","Cell RNA - OE19 [nTPM]":"38.7","Cell RNA - PC-3 [nTPM]":"45.0","Cell RNA - REH [nTPM]":"38.0","Cell RNA - RH-30 [nTPM]":"47.8","Cell RNA - RPMI-8226 [nTPM]":"36.7","Cell RNA - RPTEC TERT1 [nTPM]":"41.7","Cell RNA - RT4 [nTPM]":"13.5","Cell RNA - SCLC-21H [nTPM]":"36.5","Cell RNA - SH-SY5Y [nTPM]":"24.2","Cell RNA - SiHa [nTPM]":"34.2","Cell RNA - SK-BR-3 [nTPM]":"31.3","Cell RNA - SK-MEL-30 [nTPM]":"23.8","Cell RNA - SuSa [nTPM]":"18.1","Cell RNA - T-47d [nTPM]":"37.2","Cell RNA - THP-1 [nTPM]":"26.5","Cell RNA - TIME [nTPM]":"37.7","Cell RNA - U-138 MG [nTPM]":"71.7","Cell RNA - U-2 OS [nTPM]":"20.3","Cell RNA - U-2197 [nTPM]":"100.7","Cell RNA - U-251 MG [nTPM]":"39.6","Cell RNA - U-266\/70 [nTPM]":"31.9","Cell RNA - U-266\/84 [nTPM]":"24.9","Cell RNA - U-698 [nTPM]":"23.6","Cell RNA - U-87 MG [nTPM]":"49.6","Cell RNA - U-937 [nTPM]":"28.0","Cell RNA - WM-115 [nTPM]":"32.7","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"1.5","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"2.7","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"1.1","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"3.2","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"2.5","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"46.6","Brain RNA - basal ganglia [nTPM]":"47.6","Brain RNA - cerebellum [nTPM]":"39.9","Brain RNA - cerebral cortex [nTPM]":"64.2","Brain RNA - hippocampal formation [nTPM]":"49.2","Brain RNA - hypothalamus [nTPM]":"53.3","Brain RNA - medulla oblongata [nTPM]":"56.8","Brain RNA - midbrain [nTPM]":"54.5","Brain RNA - pons [nTPM]":"55.3","Brain RNA - spinal cord [nTPM]":"40.7","Brain RNA - thalamus [nTPM]":"50.3","Brain RNA - white matter [nTPM]":"46.6","Single Cell Type RNA - Adipocytes [nTPM]":"39.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.4","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"7.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"42.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"19.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"116.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"4.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.9","Single Cell Type RNA - dendritic cells [nTPM]":"9.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"12.4","Single Cell Type RNA - Early spermatids [nTPM]":"32.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.9","Single Cell Type RNA - Endothelial cells [nTPM]":"26.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.5","Single Cell Type RNA - Erythroid cells [nTPM]":"2.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.7","Single Cell Type RNA - Fibroblasts [nTPM]":"22.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"15.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.4","Single Cell Type RNA - Hepatocytes [nTPM]":"39.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"34.5","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.8","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"49.4","Single Cell Type RNA - Langerhans cells [nTPM]":"50.8","Single Cell Type RNA - Late spermatids [nTPM]":"15.7","Single Cell Type RNA - Leydig cells [nTPM]":"49.0","Single Cell Type RNA - Macrophages [nTPM]":"37.1","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"37.8","Single Cell Type RNA - Muller glia cells [nTPM]":"26.1","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.6","Single Cell Type RNA - Paneth cells [nTPM]":"11.6","Single Cell Type RNA - Peritubular cells [nTPM]":"51.9","Single Cell Type RNA - Plasma cells [nTPM]":"3.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.9","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.5","Single Cell Type RNA - Spermatocytes [nTPM]":"26.4","Single Cell Type RNA - Spermatogonia [nTPM]":"6.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.1","Single Cell Type RNA - T-cells [nTPM]":"10.0","Single Cell Type RNA - Theca cells [nTPM]":"100.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.4","Single Cell Type RNA - Urothelial cells [nTPM]":"6.6"},{"Gene":"PRKACG","Gene synonym":["PKACg"],"Ensembl":"ENSG00000165059","Gene description":"Protein kinase cAMP-activated catalytic subunit gamma","Uniprot":["P22612"],"Chromosome":"9","Position":"69012504-69014113","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"152","RNA tissue specific nTPM":{"testis":"24.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"27","RNA single cell type specific nTPM":{"Early spermatids":"71.0","Late spermatids":"88.4","Spermatocytes":"41.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004530","HPA071185"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Cytokinetic bridge","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Cytokinetic bridge"],"Antibody RRID":{"CAB004530":"AB_628137","HPA071185":"AB_2686356"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"24.6","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"71.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"88.4","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"41.3","Single Cell Type RNA - Spermatogonia [nTPM]":"2.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"PRKCH","Gene synonym":["PKC-L","PKCL","PRKCL"],"Ensembl":"ENSG00000027075","Gene description":"Protein kinase C eta","Uniprot":["P24723"],"Chromosome":"14","Position":"61187559-61550976","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Differentiation"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"128.4","Microglial cells":"267.9","NK-cells":"229.6","T-cells":"130.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"11","RNA blood cell specific nTPM":{"gdT-cell":"116.5","MAIT T-cell":"91.3","memory CD4 T-cell":"88.0","memory CD8 T-cell":"137.0","naive CD4 T-cell":"106.9","naive CD8 T-cell":"105.5","NK-cell":"117.1","T-reg":"79.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"14","RNA blood lineage specific nTPM":{"NK-cells":"117.1","T-cells":"137.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"81.8","HUVEC TERT2":"108.7","MOLT-4":"75.8","RT4":"46.4","TIME":"72.0"},"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"6","RNA mouse brain regional specific nTPM":{"basal ganglia":"28.0","thalamus":"17.9"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026294","HPA053709"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA026294":"AB_10603988","HPA053709":"AB_2682237"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.55e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-3"},"Tissue RNA - adipose tissue [nTPM]":"26.6","Tissue RNA - adrenal gland [nTPM]":"7.8","Tissue RNA - amygdala [nTPM]":"21.1","Tissue RNA - appendix [nTPM]":"21.9","Tissue RNA - basal ganglia [nTPM]":"30.2","Tissue RNA - bone marrow [nTPM]":"24.2","Tissue RNA - breast [nTPM]":"21.9","Tissue RNA - cerebellum [nTPM]":"12.4","Tissue RNA - cerebral cortex [nTPM]":"15.7","Tissue RNA - cervix [nTPM]":"20.6","Tissue RNA - choroid plexus [nTPM]":"9.5","Tissue RNA - colon [nTPM]":"8.9","Tissue RNA - duodenum [nTPM]":"9.5","Tissue RNA - endometrium 1 [nTPM]":"14.5","Tissue RNA - epididymis [nTPM]":"10.9","Tissue RNA - esophagus [nTPM]":"30.0","Tissue RNA - fallopian tube [nTPM]":"13.6","Tissue RNA - gallbladder [nTPM]":"19.7","Tissue RNA - heart muscle [nTPM]":"19.2","Tissue RNA - hippocampal formation [nTPM]":"13.2","Tissue RNA - hypothalamus [nTPM]":"13.9","Tissue RNA - kidney [nTPM]":"14.5","Tissue RNA - liver [nTPM]":"10.3","Tissue RNA - lung [nTPM]":"35.3","Tissue RNA - lymph node [nTPM]":"55.2","Tissue RNA - medulla oblongata [nTPM]":"19.3","Tissue RNA - midbrain [nTPM]":"21.7","Tissue RNA - ovary [nTPM]":"5.9","Tissue RNA - pancreas [nTPM]":"8.4","Tissue RNA - parathyroid gland [nTPM]":"14.2","Tissue RNA - pituitary gland [nTPM]":"15.0","Tissue RNA - placenta [nTPM]":"32.5","Tissue RNA - pons [nTPM]":"19.4","Tissue RNA - prostate [nTPM]":"15.8","Tissue RNA - rectum [nTPM]":"8.8","Tissue RNA - retina [nTPM]":"3.1","Tissue RNA - salivary gland [nTPM]":"28.3","Tissue RNA - seminal vesicle [nTPM]":"11.4","Tissue RNA - skeletal muscle [nTPM]":"14.2","Tissue RNA - skin 1 [nTPM]":"23.7","Tissue RNA - small intestine [nTPM]":"16.6","Tissue RNA - smooth muscle [nTPM]":"18.1","Tissue RNA - spinal cord [nTPM]":"18.6","Tissue RNA - spleen [nTPM]":"38.5","Tissue RNA - stomach 1 [nTPM]":"9.6","Tissue RNA - testis [nTPM]":"7.5","Tissue RNA - thalamus [nTPM]":"29.9","Tissue RNA - thymus [nTPM]":"65.8","Tissue RNA - thyroid gland [nTPM]":"21.1","Tissue RNA - tongue [nTPM]":"18.1","Tissue RNA - tonsil [nTPM]":"38.5","Tissue RNA - urinary bladder [nTPM]":"25.3","Tissue RNA - vagina [nTPM]":"21.7","Tissue RNA - white matter [nTPM]":"15.5","Cell RNA - A-431 [nTPM]":"18.1","Cell RNA - A549 [nTPM]":"6.3","Cell RNA - AF22 [nTPM]":"0.8","Cell RNA - AN3-CA [nTPM]":"4.9","Cell RNA - ASC diff [nTPM]":"2.8","Cell RNA - ASC TERT1 [nTPM]":"0.6","Cell RNA - BEWO [nTPM]":"81.8","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"1.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.8","Cell RNA - CACO-2 [nTPM]":"1.9","Cell RNA - CAPAN-2 [nTPM]":"10.5","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"12.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"1.6","Cell RNA - HaCaT [nTPM]":"12.3","Cell RNA - HAP1 [nTPM]":"0.6","Cell RNA - HBEC3-KT [nTPM]":"13.5","Cell RNA - HBF TERT88 [nTPM]":"1.4","Cell RNA - HDLM-2 [nTPM]":"2.2","Cell RNA - HEK 293 [nTPM]":"7.9","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"2.0","Cell RNA - Hep G2 [nTPM]":"0.7","Cell RNA - HHSteC [nTPM]":"1.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"2.4","Cell RNA - HSkMC [nTPM]":"2.2","Cell RNA - hTCEpi [nTPM]":"13.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.7","Cell RNA - hTERT-HME1 [nTPM]":"9.4","Cell RNA - hTERT-RPE1 [nTPM]":"1.2","Cell RNA - HUVEC TERT2 [nTPM]":"108.7","Cell RNA - JURKAT [nTPM]":"35.4","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"6.2","Cell RNA - MCF7 [nTPM]":"32.7","Cell RNA - MOLT-4 [nTPM]":"75.8","Cell RNA - NB-4 [nTPM]":"0.7","Cell RNA - NTERA-2 [nTPM]":"1.4","Cell RNA - OE19 [nTPM]":"12.9","Cell RNA - PC-3 [nTPM]":"8.4","Cell RNA - REH [nTPM]":"6.3","Cell RNA - RH-30 [nTPM]":"3.2","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"46.4","Cell RNA - SCLC-21H [nTPM]":"3.2","Cell RNA - SH-SY5Y [nTPM]":"5.1","Cell RNA - SiHa [nTPM]":"2.1","Cell RNA - SK-BR-3 [nTPM]":"16.2","Cell RNA - SK-MEL-30 [nTPM]":"10.2","Cell RNA - SuSa [nTPM]":"14.5","Cell RNA - T-47d [nTPM]":"15.9","Cell RNA - THP-1 [nTPM]":"1.4","Cell RNA - TIME [nTPM]":"72.0","Cell RNA - U-138 MG [nTPM]":"2.1","Cell RNA - U-2 OS [nTPM]":"14.0","Cell RNA - U-2197 [nTPM]":"2.1","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"1.4","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.6","Cell RNA - U-87 MG [nTPM]":"3.1","Cell RNA - U-937 [nTPM]":"1.1","Cell RNA - WM-115 [nTPM]":"3.6","Blood RNA - basophil [nTPM]":"0.8","Blood RNA - classical monocyte [nTPM]":"3.0","Blood RNA - eosinophil [nTPM]":"2.4","Blood RNA - gdT-cell [nTPM]":"116.5","Blood RNA - intermediate monocyte [nTPM]":"1.9","Blood RNA - MAIT T-cell [nTPM]":"91.3","Blood RNA - memory B-cell [nTPM]":"2.2","Blood RNA - memory CD4 T-cell [nTPM]":"88.0","Blood RNA - memory CD8 T-cell [nTPM]":"137.0","Blood RNA - myeloid DC [nTPM]":"9.2","Blood RNA - naive B-cell [nTPM]":"1.4","Blood RNA - naive CD4 T-cell [nTPM]":"106.9","Blood RNA - naive CD8 T-cell [nTPM]":"105.5","Blood RNA - neutrophil [nTPM]":"5.9","Blood RNA - NK-cell [nTPM]":"117.1","Blood RNA - non-classical monocyte [nTPM]":"1.1","Blood RNA - plasmacytoid DC [nTPM]":"3.0","Blood RNA - T-reg [nTPM]":"79.8","Blood RNA - total PBMC [nTPM]":"84.0","Brain RNA - amygdala [nTPM]":"21.1","Brain RNA - basal ganglia [nTPM]":"30.2","Brain RNA - cerebellum [nTPM]":"12.4","Brain RNA - cerebral cortex [nTPM]":"15.7","Brain RNA - hippocampal formation [nTPM]":"13.2","Brain RNA - hypothalamus [nTPM]":"13.9","Brain RNA - medulla oblongata [nTPM]":"19.3","Brain RNA - midbrain [nTPM]":"21.7","Brain RNA - pons [nTPM]":"19.4","Brain RNA - spinal cord [nTPM]":"18.6","Brain RNA - thalamus [nTPM]":"29.9","Brain RNA - white matter [nTPM]":"15.5","Single Cell Type RNA - Adipocytes [nTPM]":"59.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.4","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"6.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"15.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.6","Single Cell Type RNA - dendritic cells [nTPM]":"128.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.0","Single Cell Type RNA - Early spermatids [nTPM]":"32.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.1","Single Cell Type RNA - Endothelial cells [nTPM]":"70.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.9","Single Cell Type RNA - Erythroid cells [nTPM]":"18.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.2","Single Cell Type RNA - Fibroblasts [nTPM]":"5.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.9","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"15.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"68.9","Single Cell Type RNA - Hepatocytes [nTPM]":"2.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.7","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"14.4","Single Cell Type RNA - Langerhans cells [nTPM]":"6.9","Single Cell Type RNA - Late spermatids [nTPM]":"6.0","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"15.4","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"267.9","Single Cell Type RNA - monocytes [nTPM]":"8.9","Single Cell Type RNA - Muller glia cells [nTPM]":"7.0","Single Cell Type RNA - NK-cells [nTPM]":"229.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.4","Single Cell Type RNA - Paneth cells [nTPM]":"4.3","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"26.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"2.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"26.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"48.3","Single Cell Type RNA - T-cells [nTPM]":"130.5","Single Cell Type RNA - Theca cells [nTPM]":"1.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.3","Single Cell Type RNA - Urothelial cells [nTPM]":"26.0"},{"Gene":"PRKD1","Gene synonym":["PKC-mu","PKCM","PKD","PRKCM"],"Ensembl":"ENSG00000184304","Gene description":"Protein kinase D1","Uniprot":["Q15139"],"Chromosome":"14","Position":"29576479-30191898","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Angiogenesis","Apoptosis","Differentiation","Immunity","Inflammatory response","Innate immunity","Neurogenesis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Ectodermal dysplasia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"362.1","Excitatory neurons":"147.4","Inhibitory neurons":"171.1","Microglial cells":"89.0","Oligodendrocyte precursor cells":"390.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"10.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"21.6","fHDF\/TERT166":"19.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB018367","HPA029834"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB018367":"AB_2253119","HPA029834":"AB_10602821"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.44e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.91e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-1"},"Tissue RNA - adipose tissue [nTPM]":"8.0","Tissue RNA - adrenal gland [nTPM]":"9.6","Tissue RNA - amygdala [nTPM]":"5.6","Tissue RNA - appendix [nTPM]":"2.2","Tissue RNA - basal ganglia [nTPM]":"8.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"7.7","Tissue RNA - cerebellum [nTPM]":"6.5","Tissue RNA - cerebral cortex [nTPM]":"6.7","Tissue RNA - cervix [nTPM]":"6.4","Tissue RNA - choroid plexus [nTPM]":"3.7","Tissue RNA - colon [nTPM]":"9.5","Tissue RNA - duodenum [nTPM]":"1.0","Tissue RNA - endometrium 1 [nTPM]":"7.9","Tissue RNA - epididymis [nTPM]":"3.5","Tissue RNA - esophagus [nTPM]":"2.1","Tissue RNA - fallopian tube [nTPM]":"6.5","Tissue RNA - gallbladder [nTPM]":"4.4","Tissue RNA - heart muscle [nTPM]":"6.1","Tissue RNA - hippocampal formation [nTPM]":"7.5","Tissue RNA - hypothalamus [nTPM]":"7.5","Tissue RNA - kidney [nTPM]":"17.5","Tissue RNA - liver [nTPM]":"1.6","Tissue RNA - lung [nTPM]":"7.5","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"8.6","Tissue RNA - midbrain [nTPM]":"8.6","Tissue RNA - ovary [nTPM]":"11.2","Tissue RNA - pancreas [nTPM]":"5.4","Tissue RNA - parathyroid gland [nTPM]":"10.6","Tissue RNA - pituitary gland [nTPM]":"5.6","Tissue RNA - placenta [nTPM]":"1.9","Tissue RNA - pons [nTPM]":"8.7","Tissue RNA - prostate [nTPM]":"14.7","Tissue RNA - rectum [nTPM]":"1.3","Tissue RNA - retina [nTPM]":"4.7","Tissue RNA - salivary gland [nTPM]":"2.9","Tissue RNA - seminal vesicle [nTPM]":"9.3","Tissue RNA - skeletal muscle [nTPM]":"1.6","Tissue RNA - skin 1 [nTPM]":"2.8","Tissue RNA - small intestine [nTPM]":"3.6","Tissue RNA - smooth muscle [nTPM]":"6.3","Tissue RNA - spinal cord [nTPM]":"8.9","Tissue RNA - spleen [nTPM]":"2.3","Tissue RNA - stomach 1 [nTPM]":"4.6","Tissue RNA - testis [nTPM]":"11.7","Tissue RNA - thalamus [nTPM]":"8.1","Tissue RNA - thymus [nTPM]":"2.4","Tissue RNA - thyroid gland [nTPM]":"5.9","Tissue RNA - tongue [nTPM]":"2.6","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"13.1","Tissue RNA - vagina [nTPM]":"4.6","Tissue RNA - white matter [nTPM]":"10.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"4.4","Cell RNA - AF22 [nTPM]":"4.8","Cell RNA - AN3-CA [nTPM]":"3.1","Cell RNA - ASC diff [nTPM]":"21.6","Cell RNA - ASC TERT1 [nTPM]":"16.5","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"14.1","Cell RNA - BJ hTERT+ [nTPM]":"10.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.3","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.9","Cell RNA - fHDF\/TERT166 [nTPM]":"19.4","Cell RNA - GAMG [nTPM]":"4.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"7.9","Cell RNA - HBEC3-KT [nTPM]":"2.1","Cell RNA - HBF TERT88 [nTPM]":"6.8","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"6.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"8.8","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"18.4","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.4","Cell RNA - hTERT-HME1 [nTPM]":"1.5","Cell RNA - hTERT-RPE1 [nTPM]":"6.1","Cell RNA - HUVEC TERT2 [nTPM]":"2.6","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"1.4","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"17.4","Cell RNA - MCF7 [nTPM]":"1.8","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"2.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"9.6","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"6.3","Cell RNA - RPMI-8226 [nTPM]":"5.2","Cell RNA - RPTEC TERT1 [nTPM]":"9.7","Cell RNA - RT4 [nTPM]":"6.6","Cell RNA - SCLC-21H [nTPM]":"4.3","Cell RNA - SH-SY5Y [nTPM]":"13.0","Cell RNA - SiHa [nTPM]":"2.6","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"4.5","Cell RNA - SuSa [nTPM]":"4.6","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"5.6","Cell RNA - U-138 MG [nTPM]":"13.6","Cell RNA - U-2 OS [nTPM]":"6.7","Cell RNA - U-2197 [nTPM]":"1.0","Cell RNA - U-251 MG [nTPM]":"3.7","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"3.5","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"14.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"5.6","Brain RNA - basal ganglia [nTPM]":"8.0","Brain RNA - cerebellum [nTPM]":"6.5","Brain RNA - cerebral cortex [nTPM]":"6.7","Brain RNA - hippocampal formation [nTPM]":"7.5","Brain RNA - hypothalamus [nTPM]":"7.5","Brain RNA - medulla oblongata [nTPM]":"8.6","Brain RNA - midbrain [nTPM]":"8.6","Brain RNA - pons [nTPM]":"8.7","Brain RNA - spinal cord [nTPM]":"8.9","Brain RNA - thalamus [nTPM]":"8.1","Brain RNA - white matter [nTPM]":"10.3","Single Cell Type RNA - Adipocytes [nTPM]":"4.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.4","Single Cell Type RNA - Astrocytes [nTPM]":"362.1","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"29.4","Single Cell Type RNA - Ductal cells [nTPM]":"2.4","Single Cell Type RNA - Early spermatids [nTPM]":"39.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.2","Single Cell Type RNA - Endothelial cells [nTPM]":"6.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"147.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"6.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"18.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.8","Single Cell Type RNA - Hepatocytes [nTPM]":"2.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"171.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.9","Single Cell Type RNA - Late spermatids [nTPM]":"16.9","Single Cell Type RNA - Leydig cells [nTPM]":"7.5","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"89.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"16.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"390.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"76.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"12.8","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.5","Single Cell Type RNA - Spermatocytes [nTPM]":"3.2","Single Cell Type RNA - Spermatogonia [nTPM]":"7.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"29.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"PRKDC","Gene synonym":["DNA-PKC","DNA-PKcs","DNAPK","DNAPKc","DNPK1","HYRC","HYRC1","p350","p460","XRCC7"],"Ensembl":"ENSG00000253729","Gene description":"Protein kinase, DNA-activated, catalytic subunit","Uniprot":["P78527"],"Chromosome":"8","Position":"47773111-47960178","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Biological rhythms","DNA damage","DNA recombination","DNA repair","Immunity","Innate immunity","Ribosome biogenesis"],"Molecular function":["DNA-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005167","HPA035174"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"250000","Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 36: Stromal cells - Cell proliferation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB005167":"AB_2172845","HPA035174":"AB_2674504"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.03e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.76e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Tissue RNA - adipose tissue [nTPM]":"17.3","Tissue RNA - adrenal gland [nTPM]":"16.8","Tissue RNA - amygdala [nTPM]":"8.6","Tissue RNA - appendix [nTPM]":"14.1","Tissue RNA - basal ganglia [nTPM]":"10.7","Tissue RNA - bone marrow [nTPM]":"19.2","Tissue RNA - breast [nTPM]":"16.1","Tissue RNA - cerebellum [nTPM]":"9.8","Tissue RNA - cerebral cortex [nTPM]":"11.9","Tissue RNA - cervix [nTPM]":"18.2","Tissue RNA - choroid plexus [nTPM]":"10.8","Tissue RNA - colon [nTPM]":"16.2","Tissue RNA - duodenum [nTPM]":"7.0","Tissue RNA - endometrium 1 [nTPM]":"20.1","Tissue RNA - epididymis [nTPM]":"8.0","Tissue RNA - esophagus [nTPM]":"24.0","Tissue RNA - fallopian tube [nTPM]":"18.3","Tissue RNA - gallbladder [nTPM]":"7.4","Tissue RNA - heart muscle [nTPM]":"16.7","Tissue RNA - hippocampal formation [nTPM]":"10.6","Tissue RNA - hypothalamus [nTPM]":"9.3","Tissue RNA - kidney [nTPM]":"14.8","Tissue RNA - liver [nTPM]":"14.0","Tissue RNA - lung [nTPM]":"14.8","Tissue RNA - lymph node [nTPM]":"17.9","Tissue RNA - medulla oblongata [nTPM]":"10.4","Tissue RNA - midbrain [nTPM]":"10.0","Tissue RNA - ovary [nTPM]":"19.8","Tissue RNA - pancreas [nTPM]":"18.0","Tissue RNA - parathyroid gland [nTPM]":"14.0","Tissue RNA - pituitary gland [nTPM]":"16.3","Tissue RNA - placenta [nTPM]":"10.9","Tissue RNA - pons [nTPM]":"9.8","Tissue RNA - prostate [nTPM]":"13.5","Tissue RNA - rectum [nTPM]":"11.6","Tissue RNA - retina [nTPM]":"23.8","Tissue RNA - salivary gland [nTPM]":"16.0","Tissue RNA - seminal vesicle [nTPM]":"9.2","Tissue RNA - skeletal muscle [nTPM]":"26.4","Tissue RNA - skin 1 [nTPM]":"19.8","Tissue RNA - small intestine [nTPM]":"17.2","Tissue RNA - smooth muscle [nTPM]":"12.1","Tissue RNA - spinal cord [nTPM]":"10.6","Tissue RNA - spleen [nTPM]":"18.8","Tissue RNA - stomach 1 [nTPM]":"16.6","Tissue RNA - testis [nTPM]":"18.3","Tissue RNA - thalamus [nTPM]":"9.6","Tissue RNA - thymus [nTPM]":"27.8","Tissue RNA - thyroid gland [nTPM]":"13.4","Tissue RNA - tongue [nTPM]":"15.0","Tissue RNA - tonsil [nTPM]":"17.1","Tissue RNA - urinary bladder [nTPM]":"18.7","Tissue RNA - vagina [nTPM]":"17.5","Tissue RNA - white matter [nTPM]":"14.3","Cell RNA - A-431 [nTPM]":"123.5","Cell RNA - A549 [nTPM]":"103.4","Cell RNA - AF22 [nTPM]":"98.4","Cell RNA - AN3-CA [nTPM]":"93.9","Cell RNA - ASC diff [nTPM]":"59.9","Cell RNA - ASC TERT1 [nTPM]":"63.0","Cell RNA - BEWO [nTPM]":"41.6","Cell RNA - BJ [nTPM]":"51.2","Cell RNA - BJ hTERT+ [nTPM]":"49.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"70.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"68.9","Cell RNA - CACO-2 [nTPM]":"68.0","Cell RNA - CAPAN-2 [nTPM]":"39.6","Cell RNA - Daudi [nTPM]":"117.1","Cell RNA - EFO-21 [nTPM]":"43.1","Cell RNA - fHDF\/TERT166 [nTPM]":"63.3","Cell RNA - GAMG [nTPM]":"52.3","Cell RNA - HaCaT [nTPM]":"68.5","Cell RNA - HAP1 [nTPM]":"131.3","Cell RNA - HBEC3-KT [nTPM]":"70.2","Cell RNA - HBF TERT88 [nTPM]":"109.3","Cell RNA - HDLM-2 [nTPM]":"26.3","Cell RNA - HEK 293 [nTPM]":"81.8","Cell RNA - HEL [nTPM]":"230.2","Cell RNA - HeLa [nTPM]":"92.1","Cell RNA - Hep G2 [nTPM]":"83.7","Cell RNA - HHSteC [nTPM]":"25.8","Cell RNA - HL-60 [nTPM]":"88.6","Cell RNA - HMC-1 [nTPM]":"46.0","Cell RNA - HSkMC [nTPM]":"45.9","Cell RNA - hTCEpi [nTPM]":"22.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"111.3","Cell RNA - hTERT-HME1 [nTPM]":"115.3","Cell RNA - hTERT-RPE1 [nTPM]":"27.1","Cell RNA - HUVEC TERT2 [nTPM]":"73.4","Cell RNA - JURKAT [nTPM]":"79.5","Cell RNA - K-562 [nTPM]":"156.6","Cell RNA - Karpas-707 [nTPM]":"48.0","Cell RNA - LHCN-M2 [nTPM]":"78.8","Cell RNA - MCF7 [nTPM]":"57.7","Cell RNA - MOLT-4 [nTPM]":"125.8","Cell RNA - NB-4 [nTPM]":"72.3","Cell RNA - NTERA-2 [nTPM]":"108.6","Cell RNA - OE19 [nTPM]":"85.6","Cell RNA - PC-3 [nTPM]":"31.2","Cell RNA - REH [nTPM]":"60.8","Cell RNA - RH-30 [nTPM]":"77.3","Cell RNA - RPMI-8226 [nTPM]":"41.2","Cell RNA - RPTEC TERT1 [nTPM]":"35.5","Cell RNA - RT4 [nTPM]":"104.4","Cell RNA - SCLC-21H [nTPM]":"49.2","Cell RNA - SH-SY5Y [nTPM]":"62.5","Cell RNA - SiHa [nTPM]":"158.1","Cell RNA - SK-BR-3 [nTPM]":"50.6","Cell RNA - SK-MEL-30 [nTPM]":"51.1","Cell RNA - SuSa [nTPM]":"60.2","Cell RNA - T-47d [nTPM]":"72.6","Cell RNA - THP-1 [nTPM]":"60.1","Cell RNA - TIME [nTPM]":"86.2","Cell RNA - U-138 MG [nTPM]":"91.5","Cell RNA - U-2 OS [nTPM]":"78.0","Cell RNA - U-2197 [nTPM]":"73.0","Cell RNA - U-251 MG [nTPM]":"104.2","Cell RNA - U-266\/70 [nTPM]":"41.3","Cell RNA - U-266\/84 [nTPM]":"56.7","Cell RNA - U-698 [nTPM]":"162.8","Cell RNA - U-87 MG [nTPM]":"51.7","Cell RNA - U-937 [nTPM]":"97.9","Cell RNA - WM-115 [nTPM]":"75.6","Blood RNA - basophil [nTPM]":"11.4","Blood RNA - classical monocyte [nTPM]":"8.1","Blood RNA - eosinophil [nTPM]":"4.1","Blood RNA - gdT-cell [nTPM]":"8.7","Blood RNA - intermediate monocyte [nTPM]":"6.8","Blood RNA - MAIT T-cell [nTPM]":"11.0","Blood RNA - memory B-cell [nTPM]":"13.1","Blood RNA - memory CD4 T-cell [nTPM]":"10.8","Blood RNA - memory CD8 T-cell [nTPM]":"9.2","Blood RNA - myeloid DC [nTPM]":"6.5","Blood RNA - naive B-cell [nTPM]":"16.7","Blood RNA - naive CD4 T-cell [nTPM]":"11.2","Blood RNA - naive CD8 T-cell [nTPM]":"10.3","Blood RNA - neutrophil [nTPM]":"7.7","Blood RNA - NK-cell [nTPM]":"12.8","Blood RNA - non-classical monocyte [nTPM]":"13.7","Blood RNA - plasmacytoid DC [nTPM]":"15.3","Blood RNA - T-reg [nTPM]":"8.3","Blood RNA - total PBMC [nTPM]":"2.9","Brain RNA - amygdala [nTPM]":"8.6","Brain RNA - basal ganglia [nTPM]":"10.7","Brain RNA - cerebellum [nTPM]":"9.8","Brain RNA - cerebral cortex [nTPM]":"11.9","Brain RNA - hippocampal formation [nTPM]":"10.6","Brain RNA - hypothalamus [nTPM]":"9.3","Brain RNA - medulla oblongata [nTPM]":"10.4","Brain RNA - midbrain [nTPM]":"10.0","Brain RNA - pons [nTPM]":"9.8","Brain RNA - spinal cord [nTPM]":"10.6","Brain RNA - thalamus [nTPM]":"9.6","Brain RNA - white matter [nTPM]":"14.3","Single Cell Type RNA - Adipocytes [nTPM]":"73.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"36.1","Single Cell Type RNA - Astrocytes [nTPM]":"56.8","Single Cell Type RNA - B-cells [nTPM]":"67.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"38.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"48.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"59.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"77.4","Single Cell Type RNA - Bipolar cells [nTPM]":"103.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"63.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"64.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"82.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"44.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"42.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"125.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"61.1","Single Cell Type RNA - dendritic cells [nTPM]":"81.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"41.9","Single Cell Type RNA - Early spermatids [nTPM]":"29.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"66.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"166.5","Single Cell Type RNA - Endothelial cells [nTPM]":"59.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"25.8","Single Cell Type RNA - Erythroid cells [nTPM]":"147.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"85.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"36.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"60.6","Single Cell Type RNA - Fibroblasts [nTPM]":"73.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"55.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"72.6","Single Cell Type RNA - granulocytes [nTPM]":"45.6","Single Cell Type RNA - Granulosa cells [nTPM]":"105.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.5","Single Cell Type RNA - Hepatocytes [nTPM]":"41.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"35.9","Single Cell Type RNA - Horizontal cells [nTPM]":"104.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"77.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.2","Single Cell Type RNA - Ionocytes [nTPM]":"38.7","Single Cell Type RNA - Kupffer cells [nTPM]":"45.5","Single Cell Type RNA - Langerhans cells [nTPM]":"20.1","Single Cell Type RNA - Late spermatids [nTPM]":"15.5","Single Cell Type RNA - Leydig cells [nTPM]":"56.8","Single Cell Type RNA - Macrophages [nTPM]":"54.6","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"61.8","Single Cell Type RNA - monocytes [nTPM]":"63.6","Single Cell Type RNA - Muller glia cells [nTPM]":"73.1","Single Cell Type RNA - NK-cells [nTPM]":"57.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"82.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"76.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"34.9","Single Cell Type RNA - Paneth cells [nTPM]":"16.6","Single Cell Type RNA - Peritubular cells [nTPM]":"69.6","Single Cell Type RNA - Plasma cells [nTPM]":"69.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"57.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"50.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"111.6","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"91.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"69.3","Single Cell Type RNA - Spermatocytes [nTPM]":"100.7","Single Cell Type RNA - Spermatogonia [nTPM]":"106.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"85.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"40.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"33.0","Single Cell Type RNA - T-cells [nTPM]":"71.0","Single Cell Type RNA - Theca cells [nTPM]":"143.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"55.2","Single Cell Type RNA - Urothelial cells [nTPM]":"36.4"},{"Gene":"PRKG1","Gene synonym":["PGK","PKG","PKG1","PRKG1B","PRKGR1B"],"Ensembl":"ENSG00000185532","Gene description":"Protein kinase cGMP-dependent 1","Uniprot":["Q13976"],"Chromosome":"10","Position":"50990888-52298423","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Allosteric enzyme","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Aortic aneurysm","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"tongue":"36.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"778.3","Excitatory neurons":"244.9","Inhibitory neurons":"473.0","Microglial cells":"188.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"36","RNA blood cell specific nTPM":{"basophil":"7.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"49","RNA blood lineage specific nTPM":{"granulocytes":"7.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AN3-CA":"14.3","BJ hTERT+":"19.2","fHDF\/TERT166":"16.1","U-138 MG":"11.2","U-87 MG":"10.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007699","CAB009629"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB009629":"AB_2170663","HPA007699":"AB_1079677"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-4"},"Tissue RNA - adipose tissue [nTPM]":"7.0","Tissue RNA - adrenal gland [nTPM]":"8.3","Tissue RNA - amygdala [nTPM]":"6.4","Tissue RNA - appendix [nTPM]":"2.7","Tissue RNA - basal ganglia [nTPM]":"7.2","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"3.1","Tissue RNA - cerebellum [nTPM]":"1.4","Tissue RNA - cerebral cortex [nTPM]":"6.9","Tissue RNA - cervix [nTPM]":"10.3","Tissue RNA - choroid plexus [nTPM]":"12.4","Tissue RNA - colon [nTPM]":"5.5","Tissue RNA - duodenum [nTPM]":"2.4","Tissue RNA - endometrium 1 [nTPM]":"10.3","Tissue RNA - epididymis [nTPM]":"3.5","Tissue RNA - esophagus [nTPM]":"5.2","Tissue RNA - fallopian tube [nTPM]":"5.2","Tissue RNA - gallbladder [nTPM]":"7.0","Tissue RNA - heart muscle [nTPM]":"14.1","Tissue RNA - hippocampal formation [nTPM]":"6.6","Tissue RNA - hypothalamus [nTPM]":"10.7","Tissue RNA - kidney [nTPM]":"3.8","Tissue RNA - liver [nTPM]":"1.7","Tissue RNA - lung [nTPM]":"6.8","Tissue RNA - lymph node [nTPM]":"1.2","Tissue RNA - medulla oblongata [nTPM]":"5.1","Tissue RNA - midbrain [nTPM]":"4.6","Tissue RNA - ovary [nTPM]":"4.2","Tissue RNA - pancreas [nTPM]":"1.7","Tissue RNA - parathyroid gland [nTPM]":"9.6","Tissue RNA - pituitary gland [nTPM]":"1.3","Tissue RNA - placenta [nTPM]":"10.1","Tissue RNA - pons [nTPM]":"3.2","Tissue RNA - prostate [nTPM]":"6.4","Tissue RNA - rectum [nTPM]":"5.3","Tissue RNA - retina [nTPM]":"3.6","Tissue RNA - salivary gland [nTPM]":"4.0","Tissue RNA - seminal vesicle [nTPM]":"8.1","Tissue RNA - skeletal muscle [nTPM]":"25.8","Tissue RNA - skin 1 [nTPM]":"1.0","Tissue RNA - small intestine [nTPM]":"3.4","Tissue RNA - smooth muscle [nTPM]":"14.6","Tissue RNA - spinal cord [nTPM]":"5.3","Tissue RNA - spleen [nTPM]":"2.5","Tissue RNA - stomach 1 [nTPM]":"3.3","Tissue RNA - testis [nTPM]":"1.8","Tissue RNA - thalamus [nTPM]":"12.2","Tissue RNA - thymus [nTPM]":"1.5","Tissue RNA - thyroid gland [nTPM]":"7.0","Tissue RNA - tongue [nTPM]":"36.1","Tissue RNA - tonsil [nTPM]":"0.9","Tissue RNA - urinary bladder [nTPM]":"5.4","Tissue RNA - vagina [nTPM]":"4.2","Tissue RNA - white matter [nTPM]":"2.7","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"1.7","Cell RNA - AN3-CA [nTPM]":"14.3","Cell RNA - ASC diff [nTPM]":"6.5","Cell RNA - ASC TERT1 [nTPM]":"6.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"5.4","Cell RNA - BJ hTERT+ [nTPM]":"19.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.6","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.9","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"16.1","Cell RNA - GAMG [nTPM]":"2.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"1.7","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"5.0","Cell RNA - HEL [nTPM]":"1.0","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"5.5","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"8.1","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.8","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"5.3","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"4.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"2.5","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"3.9","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"7.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"2.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"11.2","Cell RNA - U-2 OS [nTPM]":"1.9","Cell RNA - U-2197 [nTPM]":"5.9","Cell RNA - U-251 MG [nTPM]":"3.7","Cell RNA - U-266\/70 [nTPM]":"1.5","Cell RNA - U-266\/84 [nTPM]":"0.8","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"10.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"2.5","Blood RNA - basophil [nTPM]":"7.3","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"6.4","Brain RNA - basal ganglia [nTPM]":"7.2","Brain RNA - cerebellum [nTPM]":"1.4","Brain RNA - cerebral cortex [nTPM]":"6.9","Brain RNA - hippocampal formation [nTPM]":"6.6","Brain RNA - hypothalamus [nTPM]":"10.7","Brain RNA - medulla oblongata [nTPM]":"5.1","Brain RNA - midbrain [nTPM]":"4.6","Brain RNA - pons [nTPM]":"3.2","Brain RNA - spinal cord [nTPM]":"5.3","Brain RNA - thalamus [nTPM]":"12.2","Brain RNA - white matter [nTPM]":"2.7","Single Cell Type RNA - Adipocytes [nTPM]":"10.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.8","Single Cell Type RNA - Astrocytes [nTPM]":"778.3","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"5.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"31.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.4","Single Cell Type RNA - Early spermatids [nTPM]":"56.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.7","Single Cell Type RNA - Endothelial cells [nTPM]":"7.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"3.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"244.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.2","Single Cell Type RNA - Fibroblasts [nTPM]":"24.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"473.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"2.2","Single Cell Type RNA - Late spermatids [nTPM]":"53.0","Single Cell Type RNA - Leydig cells [nTPM]":"32.6","Single Cell Type RNA - Macrophages [nTPM]":"5.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"188.3","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"23.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"24.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.8","Single Cell Type RNA - Paneth cells [nTPM]":"14.1","Single Cell Type RNA - Peritubular cells [nTPM]":"39.5","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.3","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"69.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.9","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.2","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"7.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.6","Single Cell Type RNA - Urothelial cells [nTPM]":"1.0"},{"Gene":"PRKN","Gene synonym":["AR-JP","PARK2","parkin","PDJ"],"Ensembl":"ENSG00000185345","Gene description":"Parkin RBR E3 ubiquitin protein ligase","Uniprot":["O60260"],"Chromosome":"6","Position":"161347417-162727775","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Autophagy","Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"28.3","tongue":"15.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"9.6","Alveolar cells type 2":"4.8","Distal tubular cells":"19.6","Proximal tubular cells":"6.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"3.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AN3-CA":"2.0","HEL":"4.1","HSkMC":"1.7","Karpas-707":"2.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016257","HPA036012"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 47: Non-specific - Unknown function","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB016257":"AB_628104","HPA036012":"AB_2732471"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.75e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.4","Tissue RNA - adrenal gland [nTPM]":"3.3","Tissue RNA - amygdala [nTPM]":"4.1","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"3.6","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"1.9","Tissue RNA - cerebellum [nTPM]":"0.4","Tissue RNA - cerebral cortex [nTPM]":"5.7","Tissue RNA - cervix [nTPM]":"1.3","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"2.7","Tissue RNA - duodenum [nTPM]":"1.2","Tissue RNA - endometrium 1 [nTPM]":"1.6","Tissue RNA - epididymis [nTPM]":"1.2","Tissue RNA - esophagus [nTPM]":"3.2","Tissue RNA - fallopian tube [nTPM]":"1.2","Tissue RNA - gallbladder [nTPM]":"1.5","Tissue RNA - heart muscle [nTPM]":"9.1","Tissue RNA - hippocampal formation [nTPM]":"4.6","Tissue RNA - hypothalamus [nTPM]":"1.8","Tissue RNA - kidney [nTPM]":"5.2","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"1.0","Tissue RNA - midbrain [nTPM]":"1.9","Tissue RNA - ovary [nTPM]":"2.8","Tissue RNA - pancreas [nTPM]":"1.2","Tissue RNA - parathyroid gland [nTPM]":"2.3","Tissue RNA - pituitary gland [nTPM]":"1.8","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"1.6","Tissue RNA - prostate [nTPM]":"1.2","Tissue RNA - rectum [nTPM]":"0.6","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"1.3","Tissue RNA - seminal vesicle [nTPM]":"1.4","Tissue RNA - skeletal muscle [nTPM]":"28.3","Tissue RNA - skin 1 [nTPM]":"2.0","Tissue RNA - small intestine [nTPM]":"1.0","Tissue RNA - smooth muscle [nTPM]":"1.2","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"1.0","Tissue RNA - stomach 1 [nTPM]":"1.9","Tissue RNA - testis [nTPM]":"5.3","Tissue RNA - thalamus [nTPM]":"1.9","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"1.3","Tissue RNA - tongue [nTPM]":"15.9","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"2.5","Tissue RNA - vagina [nTPM]":"1.0","Tissue RNA - white matter [nTPM]":"2.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"2.0","Cell RNA - ASC diff [nTPM]":"0.4","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"4.1","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.6","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"1.7","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"2.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.8","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"1.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.7","Blood RNA - basophil [nTPM]":"1.7","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"2.2","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"1.3","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"1.6","Blood RNA - naive CD4 T-cell [nTPM]":"1.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.8","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"4.1","Brain RNA - basal ganglia [nTPM]":"3.6","Brain RNA - cerebellum [nTPM]":"0.4","Brain RNA - cerebral cortex [nTPM]":"5.7","Brain RNA - hippocampal formation [nTPM]":"4.6","Brain RNA - hypothalamus [nTPM]":"1.8","Brain RNA - medulla oblongata [nTPM]":"1.0","Brain RNA - midbrain [nTPM]":"1.9","Brain RNA - pons [nTPM]":"1.6","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"1.9","Brain RNA - white matter [nTPM]":"2.4","Single Cell Type RNA - Adipocytes [nTPM]":"2.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"1.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.8","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.2","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"3.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"3.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PRKX","Gene synonym":["PKX1"],"Ensembl":"ENSG00000183943","Gene description":"Protein kinase X-linked","Uniprot":["P51817"],"Chromosome":"X","Position":"3604340-3713649","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Angiogenesis","Differentiation"],"Molecular function":["Developmental protein","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"thyroid gland":"33.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"108.3","Endometrial ciliated cells":"164.0","Glandular and luminal cells":"179.5","NK-cells":"139.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"11.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"74.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015324"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA015324":"AB_1855715"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.5","Tissue RNA - adrenal gland [nTPM]":"1.6","Tissue RNA - amygdala [nTPM]":"10.0","Tissue RNA - appendix [nTPM]":"9.8","Tissue RNA - basal ganglia [nTPM]":"12.9","Tissue RNA - bone marrow [nTPM]":"7.7","Tissue RNA - breast [nTPM]":"7.9","Tissue RNA - cerebellum [nTPM]":"12.6","Tissue RNA - cerebral cortex [nTPM]":"8.8","Tissue RNA - cervix [nTPM]":"7.8","Tissue RNA - choroid plexus [nTPM]":"12.7","Tissue RNA - colon [nTPM]":"6.5","Tissue RNA - duodenum [nTPM]":"5.1","Tissue RNA - endometrium 1 [nTPM]":"4.6","Tissue RNA - epididymis [nTPM]":"9.6","Tissue RNA - esophagus [nTPM]":"13.9","Tissue RNA - fallopian tube [nTPM]":"19.4","Tissue RNA - gallbladder [nTPM]":"4.4","Tissue RNA - heart muscle [nTPM]":"3.7","Tissue RNA - hippocampal formation [nTPM]":"8.3","Tissue RNA - hypothalamus [nTPM]":"14.3","Tissue RNA - kidney [nTPM]":"15.6","Tissue RNA - liver [nTPM]":"1.8","Tissue RNA - lung [nTPM]":"9.0","Tissue RNA - lymph node [nTPM]":"12.8","Tissue RNA - medulla oblongata [nTPM]":"18.1","Tissue RNA - midbrain [nTPM]":"13.8","Tissue RNA - ovary [nTPM]":"4.0","Tissue RNA - pancreas [nTPM]":"4.4","Tissue RNA - parathyroid gland [nTPM]":"3.1","Tissue RNA - pituitary gland [nTPM]":"2.0","Tissue RNA - placenta [nTPM]":"5.3","Tissue RNA - pons [nTPM]":"15.8","Tissue RNA - prostate [nTPM]":"3.8","Tissue RNA - rectum [nTPM]":"6.1","Tissue RNA - retina [nTPM]":"1.7","Tissue RNA - salivary gland [nTPM]":"6.1","Tissue RNA - seminal vesicle [nTPM]":"5.9","Tissue RNA - skeletal muscle [nTPM]":"2.2","Tissue RNA - skin 1 [nTPM]":"12.0","Tissue RNA - small intestine [nTPM]":"6.3","Tissue RNA - smooth muscle [nTPM]":"3.7","Tissue RNA - spinal cord [nTPM]":"14.5","Tissue RNA - spleen [nTPM]":"12.4","Tissue RNA - stomach 1 [nTPM]":"4.0","Tissue RNA - testis [nTPM]":"6.8","Tissue RNA - thalamus [nTPM]":"15.3","Tissue RNA - thymus [nTPM]":"15.4","Tissue RNA - thyroid gland [nTPM]":"33.8","Tissue RNA - tongue [nTPM]":"3.2","Tissue RNA - tonsil [nTPM]":"9.9","Tissue RNA - urinary bladder [nTPM]":"4.5","Tissue RNA - vagina [nTPM]":"12.4","Tissue RNA - white matter [nTPM]":"17.1","Cell RNA - A-431 [nTPM]":"9.1","Cell RNA - A549 [nTPM]":"8.3","Cell RNA - AF22 [nTPM]":"22.4","Cell RNA - AN3-CA [nTPM]":"16.7","Cell RNA - ASC diff [nTPM]":"4.2","Cell RNA - ASC TERT1 [nTPM]":"5.6","Cell RNA - BEWO [nTPM]":"20.5","Cell RNA - BJ [nTPM]":"5.3","Cell RNA - BJ hTERT+ [nTPM]":"2.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.5","Cell RNA - CACO-2 [nTPM]":"12.4","Cell RNA - CAPAN-2 [nTPM]":"6.1","Cell RNA - Daudi [nTPM]":"0.7","Cell RNA - EFO-21 [nTPM]":"5.3","Cell RNA - fHDF\/TERT166 [nTPM]":"4.3","Cell RNA - GAMG [nTPM]":"5.4","Cell RNA - HaCaT [nTPM]":"6.2","Cell RNA - HAP1 [nTPM]":"21.1","Cell RNA - HBEC3-KT [nTPM]":"16.1","Cell RNA - HBF TERT88 [nTPM]":"4.5","Cell RNA - HDLM-2 [nTPM]":"10.2","Cell RNA - HEK 293 [nTPM]":"14.7","Cell RNA - HEL [nTPM]":"10.0","Cell RNA - HeLa [nTPM]":"6.7","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"4.4","Cell RNA - HL-60 [nTPM]":"13.0","Cell RNA - HMC-1 [nTPM]":"74.7","Cell RNA - HSkMC [nTPM]":"3.8","Cell RNA - hTCEpi [nTPM]":"16.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.8","Cell RNA - hTERT-HME1 [nTPM]":"10.3","Cell RNA - hTERT-RPE1 [nTPM]":"7.1","Cell RNA - HUVEC TERT2 [nTPM]":"25.7","Cell RNA - JURKAT [nTPM]":"12.3","Cell RNA - K-562 [nTPM]":"11.8","Cell RNA - Karpas-707 [nTPM]":"12.7","Cell RNA - LHCN-M2 [nTPM]":"8.6","Cell RNA - MCF7 [nTPM]":"8.0","Cell RNA - MOLT-4 [nTPM]":"15.0","Cell RNA - NB-4 [nTPM]":"11.7","Cell RNA - NTERA-2 [nTPM]":"15.0","Cell RNA - OE19 [nTPM]":"7.0","Cell RNA - PC-3 [nTPM]":"9.4","Cell RNA - REH [nTPM]":"27.7","Cell RNA - RH-30 [nTPM]":"21.5","Cell RNA - RPMI-8226 [nTPM]":"17.2","Cell RNA - RPTEC TERT1 [nTPM]":"20.6","Cell RNA - RT4 [nTPM]":"7.6","Cell RNA - SCLC-21H [nTPM]":"14.9","Cell RNA - SH-SY5Y [nTPM]":"9.6","Cell RNA - SiHa [nTPM]":"5.6","Cell RNA - SK-BR-3 [nTPM]":"3.6","Cell RNA - SK-MEL-30 [nTPM]":"5.5","Cell RNA - SuSa [nTPM]":"35.1","Cell RNA - T-47d [nTPM]":"2.8","Cell RNA - THP-1 [nTPM]":"10.3","Cell RNA - TIME [nTPM]":"14.2","Cell RNA - U-138 MG [nTPM]":"2.2","Cell RNA - U-2 OS [nTPM]":"3.8","Cell RNA - U-2197 [nTPM]":"3.7","Cell RNA - U-251 MG [nTPM]":"3.6","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.7","Cell RNA - U-698 [nTPM]":"11.6","Cell RNA - U-87 MG [nTPM]":"1.3","Cell RNA - U-937 [nTPM]":"11.6","Cell RNA - WM-115 [nTPM]":"5.8","Blood RNA - basophil [nTPM]":"11.0","Blood RNA - classical monocyte [nTPM]":"2.0","Blood RNA - eosinophil [nTPM]":"1.2","Blood RNA - gdT-cell [nTPM]":"2.3","Blood RNA - intermediate monocyte [nTPM]":"2.4","Blood RNA - MAIT T-cell [nTPM]":"2.4","Blood RNA - memory B-cell [nTPM]":"1.6","Blood RNA - memory CD4 T-cell [nTPM]":"2.4","Blood RNA - memory CD8 T-cell [nTPM]":"2.2","Blood RNA - myeloid DC [nTPM]":"1.6","Blood RNA - naive B-cell [nTPM]":"1.5","Blood RNA - naive CD4 T-cell [nTPM]":"1.9","Blood RNA - naive CD8 T-cell [nTPM]":"2.1","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"2.4","Blood RNA - non-classical monocyte [nTPM]":"3.2","Blood RNA - plasmacytoid DC [nTPM]":"1.9","Blood RNA - T-reg [nTPM]":"1.8","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"10.0","Brain RNA - basal ganglia [nTPM]":"12.9","Brain RNA - cerebellum [nTPM]":"12.6","Brain RNA - cerebral cortex [nTPM]":"8.8","Brain RNA - hippocampal formation [nTPM]":"8.3","Brain RNA - hypothalamus [nTPM]":"14.3","Brain RNA - medulla oblongata [nTPM]":"18.1","Brain RNA - midbrain [nTPM]":"13.8","Brain RNA - pons [nTPM]":"15.8","Brain RNA - spinal cord [nTPM]":"14.5","Brain RNA - thalamus [nTPM]":"15.3","Brain RNA - white matter [nTPM]":"17.1","Single Cell Type RNA - Adipocytes [nTPM]":"32.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.4","Single Cell Type RNA - Astrocytes [nTPM]":"7.8","Single Cell Type RNA - B-cells [nTPM]":"35.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"21.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"10.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"30.8","Single Cell Type RNA - dendritic cells [nTPM]":"108.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"10.8","Single Cell Type RNA - Early spermatids [nTPM]":"11.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"164.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.8","Single Cell Type RNA - Endothelial cells [nTPM]":"19.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"7.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.8","Single Cell Type RNA - Fibroblasts [nTPM]":"10.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"179.5","Single Cell Type RNA - granulocytes [nTPM]":"85.1","Single Cell Type RNA - Granulosa cells [nTPM]":"11.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.2","Single Cell Type RNA - Hepatocytes [nTPM]":"2.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.9","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.5","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"19.4","Single Cell Type RNA - Langerhans cells [nTPM]":"24.1","Single Cell Type RNA - Late spermatids [nTPM]":"49.2","Single Cell Type RNA - Leydig cells [nTPM]":"19.9","Single Cell Type RNA - Macrophages [nTPM]":"29.0","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"39.4","Single Cell Type RNA - monocytes [nTPM]":"53.4","Single Cell Type RNA - Muller glia cells [nTPM]":"2.2","Single Cell Type RNA - NK-cells [nTPM]":"139.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.6","Single Cell Type RNA - Paneth cells [nTPM]":"13.1","Single Cell Type RNA - Peritubular cells [nTPM]":"21.8","Single Cell Type RNA - Plasma cells [nTPM]":"38.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"29.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"46.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.4","Single Cell Type RNA - Spermatocytes [nTPM]":"1.3","Single Cell Type RNA - Spermatogonia [nTPM]":"21.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"34.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"26.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.8","Single Cell Type RNA - T-cells [nTPM]":"63.5","Single Cell Type RNA - Theca cells [nTPM]":"10.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.6","Single Cell Type RNA - Urothelial cells [nTPM]":"20.4"},{"Gene":"PRMT7","Gene synonym":["FLJ10640","KIAA1933"],"Ensembl":"ENSG00000132600","Gene description":"Protein arginine methyltransferase 7","Uniprot":["Q9NVM4"],"Chromosome":"16","Position":"68310974-68358584","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Differentiation","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","Methyltransferase","Transferase"],"Disease involvement":["Disease variant","Dwarfism","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044241"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli fibrillar center"],"Antibody RRID":{"HPA044241":"AB_2678869"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.31e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.7","Tissue RNA - adrenal gland [nTPM]":"11.9","Tissue RNA - amygdala [nTPM]":"8.1","Tissue RNA - appendix [nTPM]":"6.2","Tissue RNA - basal ganglia [nTPM]":"8.3","Tissue RNA - bone marrow [nTPM]":"4.7","Tissue RNA - breast [nTPM]":"10.5","Tissue RNA - cerebellum [nTPM]":"8.4","Tissue RNA - cerebral cortex [nTPM]":"10.2","Tissue RNA - cervix [nTPM]":"9.8","Tissue RNA - choroid plexus [nTPM]":"12.0","Tissue RNA - colon [nTPM]":"10.8","Tissue RNA - duodenum [nTPM]":"3.2","Tissue RNA - endometrium 1 [nTPM]":"9.4","Tissue RNA - epididymis [nTPM]":"3.3","Tissue RNA - esophagus [nTPM]":"7.5","Tissue RNA - fallopian tube [nTPM]":"10.7","Tissue RNA - gallbladder [nTPM]":"4.3","Tissue RNA - heart muscle [nTPM]":"13.2","Tissue RNA - hippocampal formation [nTPM]":"8.3","Tissue RNA - hypothalamus [nTPM]":"8.3","Tissue RNA - kidney [nTPM]":"8.6","Tissue RNA - liver [nTPM]":"10.2","Tissue RNA - lung [nTPM]":"5.9","Tissue RNA - lymph node [nTPM]":"9.4","Tissue RNA - medulla oblongata [nTPM]":"8.9","Tissue RNA - midbrain [nTPM]":"8.4","Tissue RNA - ovary [nTPM]":"12.1","Tissue RNA - pancreas [nTPM]":"9.7","Tissue RNA - parathyroid gland [nTPM]":"4.8","Tissue RNA - pituitary gland [nTPM]":"11.1","Tissue RNA - placenta [nTPM]":"6.3","Tissue RNA - pons [nTPM]":"8.8","Tissue RNA - prostate [nTPM]":"10.5","Tissue RNA - rectum [nTPM]":"3.0","Tissue RNA - retina [nTPM]":"4.6","Tissue RNA - salivary gland [nTPM]":"10.0","Tissue RNA - seminal vesicle [nTPM]":"7.0","Tissue RNA - skeletal muscle [nTPM]":"21.8","Tissue RNA - skin 1 [nTPM]":"9.8","Tissue RNA - small intestine [nTPM]":"8.8","Tissue RNA - smooth muscle [nTPM]":"4.5","Tissue RNA - spinal cord [nTPM]":"8.3","Tissue RNA - spleen [nTPM]":"9.7","Tissue RNA - stomach 1 [nTPM]":"8.8","Tissue RNA - testis [nTPM]":"9.8","Tissue RNA - thalamus [nTPM]":"8.4","Tissue RNA - thymus [nTPM]":"14.4","Tissue RNA - thyroid gland [nTPM]":"8.6","Tissue RNA - tongue [nTPM]":"13.5","Tissue RNA - tonsil [nTPM]":"5.8","Tissue RNA - urinary bladder [nTPM]":"9.7","Tissue RNA - vagina [nTPM]":"8.3","Tissue RNA - white matter [nTPM]":"8.4","Cell RNA - A-431 [nTPM]":"18.1","Cell RNA - A549 [nTPM]":"24.7","Cell RNA - AF22 [nTPM]":"13.2","Cell RNA - AN3-CA [nTPM]":"36.1","Cell RNA - ASC diff [nTPM]":"7.1","Cell RNA - ASC TERT1 [nTPM]":"7.0","Cell RNA - BEWO [nTPM]":"50.8","Cell RNA - BJ [nTPM]":"13.8","Cell RNA - BJ hTERT+ [nTPM]":"6.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.6","Cell RNA - CACO-2 [nTPM]":"79.4","Cell RNA - CAPAN-2 [nTPM]":"16.1","Cell RNA - Daudi [nTPM]":"42.4","Cell RNA - EFO-21 [nTPM]":"29.8","Cell RNA - fHDF\/TERT166 [nTPM]":"14.0","Cell RNA - GAMG [nTPM]":"8.4","Cell RNA - HaCaT [nTPM]":"22.6","Cell RNA - HAP1 [nTPM]":"20.4","Cell RNA - HBEC3-KT [nTPM]":"13.8","Cell RNA - HBF TERT88 [nTPM]":"12.6","Cell RNA - HDLM-2 [nTPM]":"12.7","Cell RNA - HEK 293 [nTPM]":"24.5","Cell RNA - HEL [nTPM]":"8.6","Cell RNA - HeLa [nTPM]":"30.8","Cell RNA - Hep G2 [nTPM]":"36.8","Cell RNA - HHSteC [nTPM]":"7.8","Cell RNA - HL-60 [nTPM]":"24.3","Cell RNA - HMC-1 [nTPM]":"15.8","Cell RNA - HSkMC [nTPM]":"11.3","Cell RNA - hTCEpi [nTPM]":"4.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.2","Cell RNA - hTERT-HME1 [nTPM]":"14.0","Cell RNA - hTERT-RPE1 [nTPM]":"9.3","Cell RNA - HUVEC TERT2 [nTPM]":"11.8","Cell RNA - JURKAT [nTPM]":"18.7","Cell RNA - K-562 [nTPM]":"28.1","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"10.3","Cell RNA - MCF7 [nTPM]":"28.2","Cell RNA - MOLT-4 [nTPM]":"25.8","Cell RNA - NB-4 [nTPM]":"36.3","Cell RNA - NTERA-2 [nTPM]":"25.3","Cell RNA - OE19 [nTPM]":"16.5","Cell RNA - PC-3 [nTPM]":"18.8","Cell RNA - REH [nTPM]":"43.7","Cell RNA - RH-30 [nTPM]":"19.3","Cell RNA - RPMI-8226 [nTPM]":"25.7","Cell RNA - RPTEC TERT1 [nTPM]":"10.7","Cell RNA - RT4 [nTPM]":"17.7","Cell RNA - SCLC-21H [nTPM]":"19.8","Cell RNA - SH-SY5Y [nTPM]":"13.2","Cell RNA - SiHa [nTPM]":"53.5","Cell RNA - SK-BR-3 [nTPM]":"16.2","Cell RNA - SK-MEL-30 [nTPM]":"15.7","Cell RNA - SuSa [nTPM]":"11.9","Cell RNA - T-47d [nTPM]":"25.2","Cell RNA - THP-1 [nTPM]":"22.2","Cell RNA - TIME [nTPM]":"16.0","Cell RNA - U-138 MG [nTPM]":"14.7","Cell RNA - U-2 OS [nTPM]":"12.9","Cell RNA - U-2197 [nTPM]":"19.9","Cell RNA - U-251 MG [nTPM]":"17.6","Cell RNA - U-266\/70 [nTPM]":"9.6","Cell RNA - U-266\/84 [nTPM]":"22.5","Cell RNA - U-698 [nTPM]":"41.6","Cell RNA - U-87 MG [nTPM]":"17.1","Cell RNA - U-937 [nTPM]":"23.4","Cell RNA - WM-115 [nTPM]":"16.8","Blood RNA - basophil [nTPM]":"12.3","Blood RNA - classical monocyte [nTPM]":"8.2","Blood RNA - eosinophil [nTPM]":"7.1","Blood RNA - gdT-cell [nTPM]":"17.4","Blood RNA - intermediate monocyte [nTPM]":"10.6","Blood RNA - MAIT T-cell [nTPM]":"20.2","Blood RNA - memory B-cell [nTPM]":"10.9","Blood RNA - memory CD4 T-cell [nTPM]":"11.6","Blood RNA - memory CD8 T-cell [nTPM]":"14.9","Blood RNA - myeloid DC [nTPM]":"11.8","Blood RNA - naive B-cell [nTPM]":"12.8","Blood RNA - naive CD4 T-cell [nTPM]":"16.7","Blood RNA - naive CD8 T-cell [nTPM]":"15.4","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"21.4","Blood RNA - non-classical monocyte [nTPM]":"9.5","Blood RNA - plasmacytoid DC [nTPM]":"32.9","Blood RNA - T-reg [nTPM]":"14.7","Blood RNA - total PBMC [nTPM]":"14.3","Brain RNA - amygdala [nTPM]":"8.1","Brain RNA - basal ganglia [nTPM]":"8.3","Brain RNA - cerebellum [nTPM]":"8.4","Brain RNA - cerebral cortex [nTPM]":"10.2","Brain RNA - hippocampal formation [nTPM]":"8.3","Brain RNA - hypothalamus [nTPM]":"8.3","Brain RNA - medulla oblongata [nTPM]":"8.9","Brain RNA - midbrain [nTPM]":"8.4","Brain RNA - pons [nTPM]":"8.8","Brain RNA - spinal cord [nTPM]":"8.3","Brain RNA - thalamus [nTPM]":"8.4","Brain RNA - white matter [nTPM]":"8.4","Single Cell Type RNA - Adipocytes [nTPM]":"7.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.6","Single Cell Type RNA - Astrocytes [nTPM]":"16.6","Single Cell Type RNA - B-cells [nTPM]":"12.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"21.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"10.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"54.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.4","Single Cell Type RNA - dendritic cells [nTPM]":"12.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"28.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"12.3","Single Cell Type RNA - Early spermatids [nTPM]":"4.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.7","Single Cell Type RNA - Endothelial cells [nTPM]":"7.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.2","Single Cell Type RNA - Erythroid cells [nTPM]":"7.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.4","Single Cell Type RNA - Fibroblasts [nTPM]":"10.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.9","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"24.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"8.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.2","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"32.4","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"7.7","Single Cell Type RNA - Langerhans cells [nTPM]":"20.6","Single Cell Type RNA - Late spermatids [nTPM]":"4.3","Single Cell Type RNA - Leydig cells [nTPM]":"11.8","Single Cell Type RNA - Macrophages [nTPM]":"6.2","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"9.1","Single Cell Type RNA - Muller glia cells [nTPM]":"9.7","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"23.6","Single Cell Type RNA - Paneth cells [nTPM]":"29.8","Single Cell Type RNA - Peritubular cells [nTPM]":"13.2","Single Cell Type RNA - Plasma cells [nTPM]":"6.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.6","Single Cell Type RNA - Spermatocytes [nTPM]":"6.9","Single Cell Type RNA - Spermatogonia [nTPM]":"19.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.6","Single Cell Type RNA - T-cells [nTPM]":"16.5","Single Cell Type RNA - Theca cells [nTPM]":"10.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.1","Single Cell Type RNA - Urothelial cells [nTPM]":"12.7"},{"Gene":"PRNP","Gene synonym":["AltPrP","CD230","CJD","GSS","PRIP","PRP"],"Ensembl":"ENSG00000171867","Gene description":"Prion protein","Uniprot":["P04156"],"Chromosome":"20","Position":"4686350-4701590","Protein class":["CD markers","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Cell cycle","Growth arrest"],"Molecular function":["Prion"],"Disease involvement":["Amyloidosis","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"412.6","Basal squamous epithelial cells":"369.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"basophil":"875.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"875.9"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"WM-115":"1039.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042754","HPA043398"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5100000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Nuclear membrane","Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA042754":"AB_10964203","HPA043398":"AB_2678461"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.96e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.64e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.52e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.41e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Tissue RNA - adipose tissue [nTPM]":"87.0","Tissue RNA - adrenal gland [nTPM]":"92.4","Tissue RNA - amygdala [nTPM]":"283.8","Tissue RNA - appendix [nTPM]":"52.4","Tissue RNA - basal ganglia [nTPM]":"308.4","Tissue RNA - bone marrow [nTPM]":"83.7","Tissue RNA - breast [nTPM]":"106.7","Tissue RNA - cerebellum [nTPM]":"255.1","Tissue RNA - cerebral cortex [nTPM]":"385.9","Tissue RNA - cervix [nTPM]":"135.4","Tissue RNA - choroid plexus [nTPM]":"415.8","Tissue RNA - colon [nTPM]":"184.2","Tissue RNA - duodenum [nTPM]":"37.1","Tissue RNA - endometrium 1 [nTPM]":"125.5","Tissue RNA - epididymis [nTPM]":"59.1","Tissue RNA - esophagus [nTPM]":"79.2","Tissue RNA - fallopian tube [nTPM]":"79.9","Tissue RNA - gallbladder [nTPM]":"110.1","Tissue RNA - heart muscle [nTPM]":"197.5","Tissue RNA - hippocampal formation [nTPM]":"315.6","Tissue RNA - hypothalamus [nTPM]":"244.8","Tissue RNA - kidney [nTPM]":"132.8","Tissue RNA - liver [nTPM]":"79.7","Tissue RNA - lung [nTPM]":"79.2","Tissue RNA - lymph node [nTPM]":"59.8","Tissue RNA - medulla oblongata [nTPM]":"262.8","Tissue RNA - midbrain [nTPM]":"260.8","Tissue RNA - ovary [nTPM]":"163.7","Tissue RNA - pancreas [nTPM]":"41.5","Tissue RNA - parathyroid gland [nTPM]":"62.8","Tissue RNA - pituitary gland [nTPM]":"83.8","Tissue RNA - placenta [nTPM]":"66.9","Tissue RNA - pons [nTPM]":"270.1","Tissue RNA - prostate [nTPM]":"146.1","Tissue RNA - rectum [nTPM]":"70.5","Tissue RNA - retina [nTPM]":"178.6","Tissue RNA - salivary gland [nTPM]":"60.3","Tissue RNA - seminal vesicle [nTPM]":"148.2","Tissue RNA - skeletal muscle [nTPM]":"64.0","Tissue RNA - skin 1 [nTPM]":"95.4","Tissue RNA - small intestine [nTPM]":"47.4","Tissue RNA - smooth muscle [nTPM]":"140.8","Tissue RNA - spinal cord [nTPM]":"265.0","Tissue RNA - spleen [nTPM]":"75.2","Tissue RNA - stomach 1 [nTPM]":"61.6","Tissue RNA - testis [nTPM]":"68.1","Tissue RNA - thalamus [nTPM]":"302.5","Tissue RNA - thymus [nTPM]":"47.9","Tissue RNA - thyroid gland [nTPM]":"89.1","Tissue RNA - tongue [nTPM]":"74.0","Tissue RNA - tonsil [nTPM]":"60.0","Tissue RNA - urinary bladder [nTPM]":"124.9","Tissue RNA - vagina [nTPM]":"83.4","Tissue RNA - white matter [nTPM]":"292.8","Cell RNA - A-431 [nTPM]":"226.4","Cell RNA - A549 [nTPM]":"141.6","Cell RNA - AF22 [nTPM]":"41.7","Cell RNA - AN3-CA [nTPM]":"64.2","Cell RNA - ASC diff [nTPM]":"329.6","Cell RNA - ASC TERT1 [nTPM]":"199.9","Cell RNA - BEWO [nTPM]":"36.6","Cell RNA - BJ [nTPM]":"363.4","Cell RNA - BJ hTERT+ [nTPM]":"527.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"175.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"177.7","Cell RNA - CACO-2 [nTPM]":"50.0","Cell RNA - CAPAN-2 [nTPM]":"171.5","Cell RNA - Daudi [nTPM]":"40.9","Cell RNA - EFO-21 [nTPM]":"79.2","Cell RNA - fHDF\/TERT166 [nTPM]":"727.9","Cell RNA - GAMG [nTPM]":"391.8","Cell RNA - HaCaT [nTPM]":"508.8","Cell RNA - HAP1 [nTPM]":"45.9","Cell RNA - HBEC3-KT [nTPM]":"498.3","Cell RNA - HBF TERT88 [nTPM]":"326.2","Cell RNA - HDLM-2 [nTPM]":"31.8","Cell RNA - HEK 293 [nTPM]":"39.0","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"19.6","Cell RNA - Hep G2 [nTPM]":"193.8","Cell RNA - HHSteC [nTPM]":"402.0","Cell RNA - HL-60 [nTPM]":"72.8","Cell RNA - HMC-1 [nTPM]":"16.5","Cell RNA - HSkMC [nTPM]":"177.5","Cell RNA - hTCEpi [nTPM]":"711.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"701.8","Cell RNA - hTERT-HME1 [nTPM]":"583.9","Cell RNA - hTERT-RPE1 [nTPM]":"257.0","Cell RNA - HUVEC TERT2 [nTPM]":"152.8","Cell RNA - JURKAT [nTPM]":"28.6","Cell RNA - K-562 [nTPM]":"22.8","Cell RNA - Karpas-707 [nTPM]":"142.9","Cell RNA - LHCN-M2 [nTPM]":"205.1","Cell RNA - MCF7 [nTPM]":"45.7","Cell RNA - MOLT-4 [nTPM]":"28.8","Cell RNA - NB-4 [nTPM]":"46.2","Cell RNA - NTERA-2 [nTPM]":"33.1","Cell RNA - OE19 [nTPM]":"99.8","Cell RNA - PC-3 [nTPM]":"266.4","Cell RNA - REH [nTPM]":"33.9","Cell RNA - RH-30 [nTPM]":"110.0","Cell RNA - RPMI-8226 [nTPM]":"38.3","Cell RNA - RPTEC TERT1 [nTPM]":"88.7","Cell RNA - RT4 [nTPM]":"40.3","Cell RNA - SCLC-21H [nTPM]":"49.2","Cell RNA - SH-SY5Y [nTPM]":"7.0","Cell RNA - SiHa [nTPM]":"98.9","Cell RNA - SK-BR-3 [nTPM]":"144.3","Cell RNA - SK-MEL-30 [nTPM]":"554.1","Cell RNA - SuSa [nTPM]":"56.4","Cell RNA - T-47d [nTPM]":"30.2","Cell RNA - THP-1 [nTPM]":"38.8","Cell RNA - TIME [nTPM]":"224.5","Cell RNA - U-138 MG [nTPM]":"282.9","Cell RNA - U-2 OS [nTPM]":"127.1","Cell RNA - U-2197 [nTPM]":"158.6","Cell RNA - U-251 MG [nTPM]":"296.1","Cell RNA - U-266\/70 [nTPM]":"63.1","Cell RNA - U-266\/84 [nTPM]":"129.5","Cell RNA - U-698 [nTPM]":"132.9","Cell RNA - U-87 MG [nTPM]":"226.8","Cell RNA - U-937 [nTPM]":"51.9","Cell RNA - WM-115 [nTPM]":"1039.0","Blood RNA - basophil [nTPM]":"875.9","Blood RNA - classical monocyte [nTPM]":"74.1","Blood RNA - eosinophil [nTPM]":"5.4","Blood RNA - gdT-cell [nTPM]":"67.3","Blood RNA - intermediate monocyte [nTPM]":"60.9","Blood RNA - MAIT T-cell [nTPM]":"100.7","Blood RNA - memory B-cell [nTPM]":"25.1","Blood RNA - memory CD4 T-cell [nTPM]":"56.9","Blood RNA - memory CD8 T-cell [nTPM]":"55.8","Blood RNA - myeloid DC [nTPM]":"62.9","Blood RNA - naive B-cell [nTPM]":"25.6","Blood RNA - naive CD4 T-cell [nTPM]":"33.5","Blood RNA - naive CD8 T-cell [nTPM]":"40.1","Blood RNA - neutrophil [nTPM]":"4.6","Blood RNA - NK-cell [nTPM]":"23.6","Blood RNA - non-classical monocyte [nTPM]":"50.4","Blood RNA - plasmacytoid DC [nTPM]":"24.6","Blood RNA - T-reg [nTPM]":"72.8","Blood RNA - total PBMC [nTPM]":"72.7","Brain RNA - amygdala [nTPM]":"283.8","Brain RNA - basal ganglia [nTPM]":"308.4","Brain RNA - cerebellum [nTPM]":"255.1","Brain RNA - cerebral cortex [nTPM]":"385.9","Brain RNA - hippocampal formation [nTPM]":"315.6","Brain RNA - hypothalamus [nTPM]":"244.8","Brain RNA - medulla oblongata [nTPM]":"262.8","Brain RNA - midbrain [nTPM]":"260.8","Brain RNA - pons [nTPM]":"270.1","Brain RNA - spinal cord [nTPM]":"265.0","Brain RNA - thalamus [nTPM]":"302.5","Brain RNA - white matter [nTPM]":"292.8","Single Cell Type RNA - Adipocytes [nTPM]":"44.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"80.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"45.4","Single Cell Type RNA - Astrocytes [nTPM]":"120.2","Single Cell Type RNA - B-cells [nTPM]":"85.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"412.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"211.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"132.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"369.3","Single Cell Type RNA - Bipolar cells [nTPM]":"265.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"60.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"103.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"257.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"68.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"116.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.7","Single Cell Type RNA - dendritic cells [nTPM]":"71.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"58.1","Single Cell Type RNA - Early spermatids [nTPM]":"6.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"73.2","Single Cell Type RNA - Endothelial cells [nTPM]":"66.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"29.9","Single Cell Type RNA - Erythroid cells [nTPM]":"31.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"125.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.3","Single Cell Type RNA - Fibroblasts [nTPM]":"177.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.2","Single Cell Type RNA - granulocytes [nTPM]":"173.0","Single Cell Type RNA - Granulosa cells [nTPM]":"25.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"41.0","Single Cell Type RNA - Hepatocytes [nTPM]":"36.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"63.6","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"170.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.4","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"219.1","Single Cell Type RNA - Langerhans cells [nTPM]":"200.4","Single Cell Type RNA - Late spermatids [nTPM]":"13.6","Single Cell Type RNA - Leydig cells [nTPM]":"143.2","Single Cell Type RNA - Macrophages [nTPM]":"126.3","Single Cell Type RNA - Melanocytes [nTPM]":"168.9","Single Cell Type RNA - Microglial cells [nTPM]":"59.0","Single Cell Type RNA - monocytes [nTPM]":"54.5","Single Cell Type RNA - Muller glia cells [nTPM]":"142.4","Single Cell Type RNA - NK-cells [nTPM]":"42.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"95.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"158.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.7","Single Cell Type RNA - Paneth cells [nTPM]":"4.5","Single Cell Type RNA - Peritubular cells [nTPM]":"170.0","Single Cell Type RNA - Plasma cells [nTPM]":"47.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"120.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"84.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"38.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"99.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"73.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"82.3","Single Cell Type RNA - Spermatocytes [nTPM]":"36.6","Single Cell Type RNA - Spermatogonia [nTPM]":"4.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"81.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"284.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.4","Single Cell Type RNA - T-cells [nTPM]":"107.2","Single Cell Type RNA - Theca cells [nTPM]":"10.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.8","Single Cell Type RNA - Urothelial cells [nTPM]":"122.6"},{"Gene":"PRODH","Gene synonym":["HSPOX2","PIG6","PRODH1","PRODH2","TP53I6"],"Ensembl":"ENSG00000100033","Gene description":"Proline dehydrogenase 1","Uniprot":["O43272"],"Chromosome":"22","Position":"18912777-18936553","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Proline metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Schizophrenia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"49.2","skin 1":"39.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Astrocytes":"183.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"11.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"12","RNA cell line specific nTPM":{"OE19":"91.3","RPTEC TERT1":"35.9"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020361"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm","Vesicles"],"Antibody RRID":{"HPA020361":"AB_10963116"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.54e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.9","Tissue RNA - adrenal gland [nTPM]":"0.7","Tissue RNA - amygdala [nTPM]":"5.8","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"6.4","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"8.5","Tissue RNA - cerebellum [nTPM]":"3.1","Tissue RNA - cerebral cortex [nTPM]":"9.0","Tissue RNA - cervix [nTPM]":"5.0","Tissue RNA - choroid plexus [nTPM]":"34.0","Tissue RNA - colon [nTPM]":"3.1","Tissue RNA - duodenum [nTPM]":"5.6","Tissue RNA - endometrium 1 [nTPM]":"1.5","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"11.6","Tissue RNA - fallopian tube [nTPM]":"5.8","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"18.6","Tissue RNA - hippocampal formation [nTPM]":"6.5","Tissue RNA - hypothalamus [nTPM]":"2.8","Tissue RNA - kidney [nTPM]":"16.7","Tissue RNA - liver [nTPM]":"15.6","Tissue RNA - lung [nTPM]":"20.6","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"7.3","Tissue RNA - midbrain [nTPM]":"4.7","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"1.4","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"5.4","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"2.5","Tissue RNA - prostate [nTPM]":"3.2","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"4.2","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"49.2","Tissue RNA - skin 1 [nTPM]":"39.8","Tissue RNA - small intestine [nTPM]":"32.5","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"3.3","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"3.5","Tissue RNA - testis [nTPM]":"1.7","Tissue RNA - thalamus [nTPM]":"7.6","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"7.4","Tissue RNA - tongue [nTPM]":"6.2","Tissue RNA - tonsil [nTPM]":"0.8","Tissue RNA - urinary bladder [nTPM]":"4.2","Tissue RNA - vagina [nTPM]":"8.5","Tissue RNA - white matter [nTPM]":"3.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.9","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"1.1","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"2.9","Cell RNA - HAP1 [nTPM]":"3.9","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.8","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"2.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.5","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"4.5","Cell RNA - OE19 [nTPM]":"91.3","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"35.9","Cell RNA - RT4 [nTPM]":"0.9","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.8","Cell RNA - SK-BR-3 [nTPM]":"1.4","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"5.2","Cell RNA - T-47d [nTPM]":"1.4","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"5.8","Brain RNA - basal ganglia [nTPM]":"6.4","Brain RNA - cerebellum [nTPM]":"3.1","Brain RNA - cerebral cortex [nTPM]":"9.0","Brain RNA - hippocampal formation [nTPM]":"6.5","Brain RNA - hypothalamus [nTPM]":"2.8","Brain RNA - medulla oblongata [nTPM]":"7.3","Brain RNA - midbrain [nTPM]":"4.7","Brain RNA - pons [nTPM]":"2.5","Brain RNA - spinal cord [nTPM]":"3.3","Brain RNA - thalamus [nTPM]":"7.6","Brain RNA - white matter [nTPM]":"3.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.6","Single Cell Type RNA - Astrocytes [nTPM]":"183.1","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"11.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.5","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"2.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"PROKR2","Gene synonym":["dJ680N4.3","GPR73b","GPR73L1","GPRg2","KAL3","PKR2"],"Ensembl":"ENSG00000101292","Gene description":"Prokineticin receptor 2","Uniprot":["Q8NFJ6"],"Chromosome":"20","Position":"5299218-5316954","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","Hypogonadotropic hypogonadism","Kallmann syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"2.0"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"NTERA-2":"1.2","SH-SY5Y":"1.7"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"olfactory bulb":"17.0"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047281"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047281":"AB_10960057"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"1.3","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"1.4","Tissue RNA - bone marrow [nTPM]":"0.8","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.9","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"1.2","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"2.0","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"1.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"1.7","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"1.3","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.3","Brain RNA - basal ganglia [nTPM]":"1.4","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.9","Brain RNA - hippocampal formation [nTPM]":"1.2","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"2.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PROM1","Gene synonym":["AC133","CD133","CORD12","MCDR2","PROML1","RP41","STGD4"],"Ensembl":"ENSG00000007062","Gene description":"Prominin 1","Uniprot":["O43490"],"Chromosome":"4","Position":"15963076-16084378","Protein class":["CD markers","Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cone-rod dystrophy","Disease variant","Retinitis pigmentosa","Stargardt disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"retina":"272.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"581.7","Respiratory ciliated cells":"144.8","Rod photoreceptor cells":"311.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"37.2","CACO-2":"70.6","CAPAN-2":"28.9","EFO-21":"62.2","NTERA-2":"97.4","RPTEC TERT1":"91.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004922","CAB011525","HPA031053"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB011525":"AB_470302","HPA004922":"AB_1846238","HPA031053":"AB_2673713"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.56e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"4.1","Tissue RNA - appendix [nTPM]":"6.2","Tissue RNA - basal ganglia [nTPM]":"3.0","Tissue RNA - bone marrow [nTPM]":"4.0","Tissue RNA - breast [nTPM]":"27.7","Tissue RNA - cerebellum [nTPM]":"2.7","Tissue RNA - cerebral cortex [nTPM]":"3.5","Tissue RNA - cervix [nTPM]":"44.9","Tissue RNA - choroid plexus [nTPM]":"2.0","Tissue RNA - colon [nTPM]":"30.7","Tissue RNA - duodenum [nTPM]":"12.4","Tissue RNA - endometrium 1 [nTPM]":"6.0","Tissue RNA - epididymis [nTPM]":"4.3","Tissue RNA - esophagus [nTPM]":"5.1","Tissue RNA - fallopian tube [nTPM]":"5.4","Tissue RNA - gallbladder [nTPM]":"30.9","Tissue RNA - heart muscle [nTPM]":"6.7","Tissue RNA - hippocampal formation [nTPM]":"3.3","Tissue RNA - hypothalamus [nTPM]":"2.8","Tissue RNA - kidney [nTPM]":"20.9","Tissue RNA - liver [nTPM]":"1.8","Tissue RNA - lung [nTPM]":"3.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"3.8","Tissue RNA - midbrain [nTPM]":"4.3","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"14.4","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"30.1","Tissue RNA - pons [nTPM]":"3.6","Tissue RNA - prostate [nTPM]":"2.8","Tissue RNA - rectum [nTPM]":"16.7","Tissue RNA - retina [nTPM]":"272.9","Tissue RNA - salivary gland [nTPM]":"57.9","Tissue RNA - seminal vesicle [nTPM]":"7.1","Tissue RNA - skeletal muscle [nTPM]":"1.0","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"22.9","Tissue RNA - smooth muscle [nTPM]":"3.5","Tissue RNA - spinal cord [nTPM]":"2.8","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"24.8","Tissue RNA - testis [nTPM]":"8.0","Tissue RNA - thalamus [nTPM]":"5.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"4.8","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"4.2","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"3.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"37.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"70.6","Cell RNA - CAPAN-2 [nTPM]":"28.9","Cell RNA - Daudi [nTPM]":"0.6","Cell RNA - EFO-21 [nTPM]":"62.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"7.3","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"1.5","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"97.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"1.4","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"91.1","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"12.0","Cell RNA - SH-SY5Y [nTPM]":"3.6","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"2.4","Cell RNA - SK-MEL-30 [nTPM]":"1.9","Cell RNA - SuSa [nTPM]":"3.5","Cell RNA - T-47d [nTPM]":"0.6","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.1","Brain RNA - basal ganglia [nTPM]":"3.0","Brain RNA - cerebellum [nTPM]":"2.7","Brain RNA - cerebral cortex [nTPM]":"3.5","Brain RNA - hippocampal formation [nTPM]":"3.3","Brain RNA - hypothalamus [nTPM]":"2.8","Brain RNA - medulla oblongata [nTPM]":"3.8","Brain RNA - midbrain [nTPM]":"4.3","Brain RNA - pons [nTPM]":"3.6","Brain RNA - spinal cord [nTPM]":"2.8","Brain RNA - thalamus [nTPM]":"5.0","Brain RNA - white matter [nTPM]":"3.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"14.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"38.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"31.5","Single Cell Type RNA - Club cells [nTPM]":"29.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"82.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"581.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.6","Single Cell Type RNA - dendritic cells [nTPM]":"1.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"39.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"64.1","Single Cell Type RNA - Early spermatids [nTPM]":"31.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"71.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.7","Single Cell Type RNA - Endothelial cells [nTPM]":"5.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"44.4","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"4.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"31.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.0","Single Cell Type RNA - Ionocytes [nTPM]":"34.6","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"44.3","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"27.2","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"47.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"45.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"38.2","Single Cell Type RNA - Paneth cells [nTPM]":"28.3","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"144.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"311.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.1","Single Cell Type RNA - Spermatocytes [nTPM]":"2.1","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.7","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.0","Single Cell Type RNA - Urothelial cells [nTPM]":"4.1"},{"Gene":"PRPH2","Gene synonym":["CACD2","rd2","RDS","RP7","TSPAN22"],"Ensembl":"ENSG00000112619","Gene description":"Peripherin 2","Uniprot":["P23942"],"Chromosome":"6","Position":"42696598-42722597","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion","Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Cone-rod dystrophy","Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"48","RNA tissue specific nTPM":{"retina":"641.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"260.6","Rod photoreceptor cells":"482.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"3.0","ASC TERT1":"3.4","fHDF\/TERT166":"5.3","HHSteC":"7.8","HSkMC":"6.0","LHCN-M2":"3.5"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"7","RNA mouse brain regional specific nTPM":{"hippocampal formation":"2.4"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029458"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029458":"AB_10602193"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-3"},"Tissue RNA - adipose tissue [nTPM]":"1.1","Tissue RNA - adrenal gland [nTPM]":"0.8","Tissue RNA - amygdala [nTPM]":"2.1","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"1.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"0.4","Tissue RNA - cerebral cortex [nTPM]":"1.8","Tissue RNA - cervix [nTPM]":"2.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"2.2","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"2.1","Tissue RNA - epididymis [nTPM]":"1.8","Tissue RNA - esophagus [nTPM]":"0.7","Tissue RNA - fallopian tube [nTPM]":"1.3","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"1.5","Tissue RNA - hippocampal formation [nTPM]":"3.1","Tissue RNA - hypothalamus [nTPM]":"2.1","Tissue RNA - kidney [nTPM]":"1.4","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"1.5","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.9","Tissue RNA - midbrain [nTPM]":"1.0","Tissue RNA - ovary [nTPM]":"3.1","Tissue RNA - pancreas [nTPM]":"2.3","Tissue RNA - parathyroid gland [nTPM]":"4.3","Tissue RNA - pituitary gland [nTPM]":"2.5","Tissue RNA - placenta [nTPM]":"0.9","Tissue RNA - pons [nTPM]":"1.2","Tissue RNA - prostate [nTPM]":"1.5","Tissue RNA - rectum [nTPM]":"0.8","Tissue RNA - retina [nTPM]":"641.4","Tissue RNA - salivary gland [nTPM]":"0.7","Tissue RNA - seminal vesicle [nTPM]":"1.1","Tissue RNA - skeletal muscle [nTPM]":"13.2","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"1.4","Tissue RNA - smooth muscle [nTPM]":"1.9","Tissue RNA - spinal cord [nTPM]":"0.4","Tissue RNA - spleen [nTPM]":"0.8","Tissue RNA - stomach 1 [nTPM]":"1.2","Tissue RNA - testis [nTPM]":"3.7","Tissue RNA - thalamus [nTPM]":"2.7","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"4.1","Tissue RNA - tongue [nTPM]":"2.9","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"1.2","Tissue RNA - vagina [nTPM]":"1.1","Tissue RNA - white matter [nTPM]":"1.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"3.0","Cell RNA - ASC TERT1 [nTPM]":"3.4","Cell RNA - BEWO [nTPM]":"0.7","Cell RNA - BJ [nTPM]":"0.9","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"5.3","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"7.8","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"6.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.9","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"3.5","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.6","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.9","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.1","Brain RNA - basal ganglia [nTPM]":"1.5","Brain RNA - cerebellum [nTPM]":"0.4","Brain RNA - cerebral cortex [nTPM]":"1.8","Brain RNA - hippocampal formation [nTPM]":"3.1","Brain RNA - hypothalamus [nTPM]":"2.1","Brain RNA - medulla oblongata [nTPM]":"0.9","Brain RNA - midbrain [nTPM]":"1.0","Brain RNA - pons [nTPM]":"1.2","Brain RNA - spinal cord [nTPM]":"0.4","Brain RNA - thalamus [nTPM]":"2.7","Brain RNA - white matter [nTPM]":"1.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"39.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"260.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.9","Single Cell Type RNA - Endothelial cells [nTPM]":"2.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"42.6","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"482.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.8","Single Cell Type RNA - Spermatocytes [nTPM]":"2.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"1.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"PRPS1","Gene synonym":["CMTX5","DFN2","DFNX1"],"Ensembl":"ENSG00000147224","Gene description":"Phosphoribosyl pyrophosphate synthetase 1","Uniprot":["P60891"],"Chromosome":"X","Position":"107628428-107651993","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Nucleotide biosynthesis"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Charcot-Marie-Tooth disease","Deafness","Disease variant","Gout","Mental retardation","Neurodegeneration","Neuropathy","Non-syndromic deafness","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043760","HPA051269"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"320000","Blood expression cluster":"Cluster 13: T-cells - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA043760":"AB_2678656","HPA051269":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Tissue RNA - adipose tissue [nTPM]":"22.9","Tissue RNA - adrenal gland [nTPM]":"28.0","Tissue RNA - amygdala [nTPM]":"33.7","Tissue RNA - appendix [nTPM]":"30.2","Tissue RNA - basal ganglia [nTPM]":"35.0","Tissue RNA - bone marrow [nTPM]":"58.0","Tissue RNA - breast [nTPM]":"21.0","Tissue RNA - cerebellum [nTPM]":"32.4","Tissue RNA - cerebral cortex [nTPM]":"36.4","Tissue RNA - cervix [nTPM]":"20.0","Tissue RNA - choroid plexus [nTPM]":"59.3","Tissue RNA - colon [nTPM]":"19.0","Tissue RNA - duodenum [nTPM]":"11.0","Tissue RNA - endometrium 1 [nTPM]":"23.7","Tissue RNA - epididymis [nTPM]":"14.8","Tissue RNA - esophagus [nTPM]":"13.7","Tissue RNA - fallopian tube [nTPM]":"25.9","Tissue RNA - gallbladder [nTPM]":"13.9","Tissue RNA - heart muscle [nTPM]":"22.2","Tissue RNA - hippocampal formation [nTPM]":"33.7","Tissue RNA - hypothalamus [nTPM]":"39.6","Tissue RNA - kidney [nTPM]":"27.6","Tissue RNA - liver [nTPM]":"51.5","Tissue RNA - lung [nTPM]":"21.5","Tissue RNA - lymph node [nTPM]":"42.7","Tissue RNA - medulla oblongata [nTPM]":"35.4","Tissue RNA - midbrain [nTPM]":"39.1","Tissue RNA - ovary [nTPM]":"30.2","Tissue RNA - pancreas [nTPM]":"21.7","Tissue RNA - parathyroid gland [nTPM]":"27.2","Tissue RNA - pituitary gland [nTPM]":"23.2","Tissue RNA - placenta [nTPM]":"14.6","Tissue RNA - pons [nTPM]":"37.6","Tissue RNA - prostate [nTPM]":"21.3","Tissue RNA - rectum [nTPM]":"17.9","Tissue RNA - retina [nTPM]":"30.2","Tissue RNA - salivary gland [nTPM]":"16.3","Tissue RNA - seminal vesicle [nTPM]":"17.4","Tissue RNA - skeletal muscle [nTPM]":"49.1","Tissue RNA - skin 1 [nTPM]":"12.3","Tissue RNA - small intestine [nTPM]":"16.7","Tissue RNA - smooth muscle [nTPM]":"29.5","Tissue RNA - spinal cord [nTPM]":"34.2","Tissue RNA - spleen [nTPM]":"26.2","Tissue RNA - stomach 1 [nTPM]":"15.5","Tissue RNA - testis [nTPM]":"13.4","Tissue RNA - thalamus [nTPM]":"35.2","Tissue RNA - thymus [nTPM]":"52.0","Tissue RNA - thyroid gland [nTPM]":"44.1","Tissue RNA - tongue [nTPM]":"37.9","Tissue RNA - tonsil [nTPM]":"45.7","Tissue RNA - urinary bladder [nTPM]":"23.6","Tissue RNA - vagina [nTPM]":"15.2","Tissue RNA - white matter [nTPM]":"34.4","Cell RNA - A-431 [nTPM]":"93.5","Cell RNA - A549 [nTPM]":"128.9","Cell RNA - AF22 [nTPM]":"56.4","Cell RNA - AN3-CA [nTPM]":"69.9","Cell RNA - ASC diff [nTPM]":"32.7","Cell RNA - ASC TERT1 [nTPM]":"26.5","Cell RNA - BEWO [nTPM]":"18.6","Cell RNA - BJ [nTPM]":"253.2","Cell RNA - BJ hTERT+ [nTPM]":"55.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"146.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"122.6","Cell RNA - CACO-2 [nTPM]":"55.5","Cell RNA - CAPAN-2 [nTPM]":"36.6","Cell RNA - Daudi [nTPM]":"156.9","Cell RNA - EFO-21 [nTPM]":"111.7","Cell RNA - fHDF\/TERT166 [nTPM]":"94.9","Cell RNA - GAMG [nTPM]":"104.1","Cell RNA - HaCaT [nTPM]":"36.6","Cell RNA - HAP1 [nTPM]":"176.0","Cell RNA - HBEC3-KT [nTPM]":"53.8","Cell RNA - HBF TERT88 [nTPM]":"148.3","Cell RNA - HDLM-2 [nTPM]":"79.9","Cell RNA - HEK 293 [nTPM]":"150.9","Cell RNA - HEL [nTPM]":"84.2","Cell RNA - HeLa [nTPM]":"140.0","Cell RNA - Hep G2 [nTPM]":"100.3","Cell RNA - HHSteC [nTPM]":"28.8","Cell RNA - HL-60 [nTPM]":"153.1","Cell RNA - HMC-1 [nTPM]":"55.6","Cell RNA - HSkMC [nTPM]":"28.2","Cell RNA - hTCEpi [nTPM]":"30.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"90.2","Cell RNA - hTERT-HME1 [nTPM]":"56.2","Cell RNA - hTERT-RPE1 [nTPM]":"96.7","Cell RNA - HUVEC TERT2 [nTPM]":"52.3","Cell RNA - JURKAT [nTPM]":"108.2","Cell RNA - K-562 [nTPM]":"137.4","Cell RNA - Karpas-707 [nTPM]":"183.5","Cell RNA - LHCN-M2 [nTPM]":"69.0","Cell RNA - MCF7 [nTPM]":"51.0","Cell RNA - MOLT-4 [nTPM]":"101.2","Cell RNA - NB-4 [nTPM]":"113.6","Cell RNA - NTERA-2 [nTPM]":"213.5","Cell RNA - OE19 [nTPM]":"77.2","Cell RNA - PC-3 [nTPM]":"141.4","Cell RNA - REH [nTPM]":"117.6","Cell RNA - RH-30 [nTPM]":"96.3","Cell RNA - RPMI-8226 [nTPM]":"125.4","Cell RNA - RPTEC TERT1 [nTPM]":"60.7","Cell RNA - RT4 [nTPM]":"54.2","Cell RNA - SCLC-21H [nTPM]":"96.2","Cell RNA - SH-SY5Y [nTPM]":"52.5","Cell RNA - SiHa [nTPM]":"131.5","Cell RNA - SK-BR-3 [nTPM]":"77.6","Cell RNA - SK-MEL-30 [nTPM]":"57.3","Cell RNA - SuSa [nTPM]":"106.4","Cell RNA - T-47d [nTPM]":"36.0","Cell RNA - THP-1 [nTPM]":"61.7","Cell RNA - TIME [nTPM]":"31.2","Cell RNA - U-138 MG [nTPM]":"93.2","Cell RNA - U-2 OS [nTPM]":"45.0","Cell RNA - U-2197 [nTPM]":"108.3","Cell RNA - U-251 MG [nTPM]":"109.1","Cell RNA - U-266\/70 [nTPM]":"61.8","Cell RNA - U-266\/84 [nTPM]":"115.1","Cell RNA - U-698 [nTPM]":"172.7","Cell RNA - U-87 MG [nTPM]":"50.1","Cell RNA - U-937 [nTPM]":"163.6","Cell RNA - WM-115 [nTPM]":"61.6","Blood RNA - basophil [nTPM]":"8.8","Blood RNA - classical monocyte [nTPM]":"8.9","Blood RNA - eosinophil [nTPM]":"22.6","Blood RNA - gdT-cell [nTPM]":"26.0","Blood RNA - intermediate monocyte [nTPM]":"14.3","Blood RNA - MAIT T-cell [nTPM]":"30.8","Blood RNA - memory B-cell [nTPM]":"29.3","Blood RNA - memory CD4 T-cell [nTPM]":"31.7","Blood RNA - memory CD8 T-cell [nTPM]":"32.2","Blood RNA - myeloid DC [nTPM]":"11.4","Blood RNA - naive B-cell [nTPM]":"31.0","Blood RNA - naive CD4 T-cell [nTPM]":"36.1","Blood RNA - naive CD8 T-cell [nTPM]":"30.7","Blood RNA - neutrophil [nTPM]":"4.7","Blood RNA - NK-cell [nTPM]":"28.5","Blood RNA - non-classical monocyte [nTPM]":"15.7","Blood RNA - plasmacytoid DC [nTPM]":"16.3","Blood RNA - T-reg [nTPM]":"35.5","Blood RNA - total PBMC [nTPM]":"21.1","Brain RNA - amygdala [nTPM]":"33.7","Brain RNA - basal ganglia [nTPM]":"35.0","Brain RNA - cerebellum [nTPM]":"32.4","Brain RNA - cerebral cortex [nTPM]":"36.4","Brain RNA - hippocampal formation [nTPM]":"33.7","Brain RNA - hypothalamus [nTPM]":"39.6","Brain RNA - medulla oblongata [nTPM]":"35.4","Brain RNA - midbrain [nTPM]":"39.1","Brain RNA - pons [nTPM]":"37.6","Brain RNA - spinal cord [nTPM]":"34.2","Brain RNA - thalamus [nTPM]":"35.2","Brain RNA - white matter [nTPM]":"34.4","Single Cell Type RNA - Adipocytes [nTPM]":"21.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.0","Single Cell Type RNA - Astrocytes [nTPM]":"4.6","Single Cell Type RNA - B-cells [nTPM]":"44.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"31.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.0","Single Cell Type RNA - Bipolar cells [nTPM]":"28.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"12.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.8","Single Cell Type RNA - dendritic cells [nTPM]":"29.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"25.4","Single Cell Type RNA - Ductal cells [nTPM]":"18.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.3","Single Cell Type RNA - Endothelial cells [nTPM]":"18.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.2","Single Cell Type RNA - Erythroid cells [nTPM]":"52.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"20.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.5","Single Cell Type RNA - Fibroblasts [nTPM]":"22.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.7","Single Cell Type RNA - granulocytes [nTPM]":"26.6","Single Cell Type RNA - Granulosa cells [nTPM]":"13.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"57.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"35.3","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.5","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"18.6","Single Cell Type RNA - Langerhans cells [nTPM]":"34.8","Single Cell Type RNA - Late spermatids [nTPM]":"3.9","Single Cell Type RNA - Leydig cells [nTPM]":"14.0","Single Cell Type RNA - Macrophages [nTPM]":"16.8","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"24.9","Single Cell Type RNA - Muller glia cells [nTPM]":"20.0","Single Cell Type RNA - NK-cells [nTPM]":"27.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.1","Single Cell Type RNA - Paneth cells [nTPM]":"3.7","Single Cell Type RNA - Peritubular cells [nTPM]":"17.0","Single Cell Type RNA - Plasma cells [nTPM]":"35.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"29.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"27.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"30.7","Single Cell Type RNA - Spermatocytes [nTPM]":"3.6","Single Cell Type RNA - Spermatogonia [nTPM]":"10.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.8","Single Cell Type RNA - T-cells [nTPM]":"45.0","Single Cell Type RNA - Theca cells [nTPM]":"19.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.0","Single Cell Type RNA - Urothelial cells [nTPM]":"9.7"},{"Gene":"PRRT2","Gene synonym":["DKFZp547J199","DSPB3","DYT10","EKD1","FICCA","FLJ25513","ICCA","IFITMD1","PKC"],"Ensembl":"ENSG00000167371","Gene description":"Proline rich transmembrane protein 2","Uniprot":["Q7Z6L0"],"Chromosome":"16","Position":"29811382-29815892","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Dystonia","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"ovary":"124.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"82.3","Cone photoreceptor cells":"31.3","Leydig cells":"36.1","Peritubular cells":"40.3","Rod photoreceptor cells":"37.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"5.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"NK-cell":"3.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"NK-cells":"3.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"24.1","HeLa":"13.8","hTERT-RPE1":"14.0","REH":"17.6","U-138 MG":"14.5"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014447","HPA019203","HPA048045"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA014447":"AB_1855786","HPA019203":"AB_2670097","HPA048045":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Tissue RNA - adipose tissue [nTPM]":"13.4","Tissue RNA - adrenal gland [nTPM]":"10.5","Tissue RNA - amygdala [nTPM]":"32.9","Tissue RNA - appendix [nTPM]":"2.4","Tissue RNA - basal ganglia [nTPM]":"40.4","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"10.8","Tissue RNA - cerebellum [nTPM]":"70.7","Tissue RNA - cerebral cortex [nTPM]":"70.5","Tissue RNA - cervix [nTPM]":"79.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"33.9","Tissue RNA - duodenum [nTPM]":"5.3","Tissue RNA - endometrium 1 [nTPM]":"39.5","Tissue RNA - epididymis [nTPM]":"8.6","Tissue RNA - esophagus [nTPM]":"6.7","Tissue RNA - fallopian tube [nTPM]":"47.0","Tissue RNA - gallbladder [nTPM]":"10.9","Tissue RNA - heart muscle [nTPM]":"15.6","Tissue RNA - hippocampal formation [nTPM]":"46.0","Tissue RNA - hypothalamus [nTPM]":"20.1","Tissue RNA - kidney [nTPM]":"8.7","Tissue RNA - liver [nTPM]":"2.4","Tissue RNA - lung [nTPM]":"12.9","Tissue RNA - lymph node [nTPM]":"3.3","Tissue RNA - medulla oblongata [nTPM]":"15.6","Tissue RNA - midbrain [nTPM]":"8.0","Tissue RNA - ovary [nTPM]":"124.3","Tissue RNA - pancreas [nTPM]":"4.7","Tissue RNA - parathyroid gland [nTPM]":"4.3","Tissue RNA - pituitary gland [nTPM]":"85.6","Tissue RNA - placenta [nTPM]":"7.0","Tissue RNA - pons [nTPM]":"16.2","Tissue RNA - prostate [nTPM]":"39.1","Tissue RNA - rectum [nTPM]":"2.3","Tissue RNA - retina [nTPM]":"19.8","Tissue RNA - salivary gland [nTPM]":"5.4","Tissue RNA - seminal vesicle [nTPM]":"13.9","Tissue RNA - skeletal muscle [nTPM]":"4.5","Tissue RNA - skin 1 [nTPM]":"5.0","Tissue RNA - small intestine [nTPM]":"14.5","Tissue RNA - smooth muscle [nTPM]":"10.4","Tissue RNA - spinal cord [nTPM]":"24.5","Tissue RNA - spleen [nTPM]":"1.7","Tissue RNA - stomach 1 [nTPM]":"12.4","Tissue RNA - testis [nTPM]":"14.6","Tissue RNA - thalamus [nTPM]":"29.2","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"10.6","Tissue RNA - tongue [nTPM]":"1.8","Tissue RNA - tonsil [nTPM]":"1.0","Tissue RNA - urinary bladder [nTPM]":"34.1","Tissue RNA - vagina [nTPM]":"51.0","Tissue RNA - white matter [nTPM]":"34.0","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"1.5","Cell RNA - AF22 [nTPM]":"24.1","Cell RNA - AN3-CA [nTPM]":"8.6","Cell RNA - ASC diff [nTPM]":"1.2","Cell RNA - ASC TERT1 [nTPM]":"4.2","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"2.5","Cell RNA - BJ hTERT+ [nTPM]":"4.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.8","Cell RNA - CACO-2 [nTPM]":"1.1","Cell RNA - CAPAN-2 [nTPM]":"1.5","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"4.4","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"1.6","Cell RNA - HAP1 [nTPM]":"3.4","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"4.1","Cell RNA - HEK 293 [nTPM]":"1.4","Cell RNA - HEL [nTPM]":"1.7","Cell RNA - HeLa [nTPM]":"13.8","Cell RNA - Hep G2 [nTPM]":"1.6","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"4.1","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.9","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"14.0","Cell RNA - HUVEC TERT2 [nTPM]":"1.0","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"1.5","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"3.1","Cell RNA - MOLT-4 [nTPM]":"0.6","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"5.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"1.1","Cell RNA - REH [nTPM]":"17.6","Cell RNA - RH-30 [nTPM]":"0.9","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.8","Cell RNA - SCLC-21H [nTPM]":"4.1","Cell RNA - SH-SY5Y [nTPM]":"4.3","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"2.1","Cell RNA - SK-MEL-30 [nTPM]":"0.5","Cell RNA - SuSa [nTPM]":"3.5","Cell RNA - T-47d [nTPM]":"7.6","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"1.3","Cell RNA - U-138 MG [nTPM]":"14.5","Cell RNA - U-2 OS [nTPM]":"5.2","Cell RNA - U-2197 [nTPM]":"0.7","Cell RNA - U-251 MG [nTPM]":"1.4","Cell RNA - U-266\/70 [nTPM]":"3.7","Cell RNA - U-266\/84 [nTPM]":"0.5","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"5.3","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"3.2","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"32.9","Brain RNA - basal ganglia [nTPM]":"40.4","Brain RNA - cerebellum [nTPM]":"70.7","Brain RNA - cerebral cortex [nTPM]":"70.5","Brain RNA - hippocampal formation [nTPM]":"46.0","Brain RNA - hypothalamus [nTPM]":"20.1","Brain RNA - medulla oblongata [nTPM]":"15.6","Brain RNA - midbrain [nTPM]":"8.0","Brain RNA - pons [nTPM]":"16.2","Brain RNA - spinal cord [nTPM]":"24.5","Brain RNA - thalamus [nTPM]":"29.2","Brain RNA - white matter [nTPM]":"34.0","Single Cell Type RNA - Adipocytes [nTPM]":"2.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"22.9","Single Cell Type RNA - B-cells [nTPM]":"0.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"82.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"1.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - dendritic cells [nTPM]":"1.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.1","Single Cell Type RNA - Early spermatids [nTPM]":"2.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.4","Single Cell Type RNA - Endothelial cells [nTPM]":"5.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.1","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"24.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.8","Single Cell Type RNA - Fibroblasts [nTPM]":"11.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.4","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"19.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.2","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"2.4","Single Cell Type RNA - Late spermatids [nTPM]":"9.8","Single Cell Type RNA - Leydig cells [nTPM]":"36.1","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"5.7","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.0","Single Cell Type RNA - Paneth cells [nTPM]":"9.0","Single Cell Type RNA - Peritubular cells [nTPM]":"40.3","Single Cell Type RNA - Plasma cells [nTPM]":"0.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"37.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.7","Single Cell Type RNA - Spermatocytes [nTPM]":"2.4","Single Cell Type RNA - Spermatogonia [nTPM]":"3.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.6","Single Cell Type RNA - T-cells [nTPM]":"2.7","Single Cell Type RNA - Theca cells [nTPM]":"0.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.5","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"PRSS1","Gene synonym":["TRY1"],"Ensembl":"ENSG00000204983","Gene description":"Serine protease 1","Uniprot":["P07477"],"Chromosome":"7","Position":"142749468-142753076","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Digestion"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"1923","RNA tissue specific nTPM":{"pancreas":"341429.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"28","RNA single cell type specific nTPM":{"Exocrine glandular cells":"57138.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"224","RNA cancer specific FPKM":{"pancreatic cancer":"1920.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"23","RNA cell line specific nTPM":{"OE19":"10.6","RPMI-8226":"4.5","U-2 OS":"2.8"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025487","CAB025538","HPA062452","HPA063471"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Vesicles"],"Secretome location":"Secreted to digestive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"100000000000","Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 1: Pancreatic cells - Digestion","Subcellular main location":["Vesicles"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"CAB025487":null,"CAB025538":null,"HPA062452":"AB_2684768","HPA063471":"AB_2685017"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.41e-6"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.05e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.91e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Tissue RNA - adipose tissue [nTPM]":"45.2","Tissue RNA - adrenal gland [nTPM]":"9.9","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"4.7","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"25.7","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"19.9","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"11.2","Tissue RNA - duodenum [nTPM]":"54.5","Tissue RNA - endometrium 1 [nTPM]":"8.9","Tissue RNA - epididymis [nTPM]":"0.8","Tissue RNA - esophagus [nTPM]":"15.2","Tissue RNA - fallopian tube [nTPM]":"5.6","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"51.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"9.6","Tissue RNA - liver [nTPM]":"29.7","Tissue RNA - lung [nTPM]":"6.4","Tissue RNA - lymph node [nTPM]":"6.5","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"177.5","Tissue RNA - pancreas [nTPM]":"341429.7","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"10.3","Tissue RNA - placenta [nTPM]":"13.9","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"15.2","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"44.2","Tissue RNA - seminal vesicle [nTPM]":"4.2","Tissue RNA - skeletal muscle [nTPM]":"8.9","Tissue RNA - skin 1 [nTPM]":"12.1","Tissue RNA - small intestine [nTPM]":"12.7","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"13.4","Tissue RNA - stomach 1 [nTPM]":"77.1","Tissue RNA - testis [nTPM]":"6.9","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"6.4","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"4.7","Tissue RNA - vagina [nTPM]":"8.5","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"10.6","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"4.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"2.8","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"100.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"3.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"57138.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"6.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"119.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1985.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"PRSS12","Gene synonym":["BSSP-3","MRT1"],"Ensembl":"ENSG00000164099","Gene description":"Serine protease 12","Uniprot":["P56730"],"Chromosome":"4","Position":"118280038-118353003","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Club cells":"34.3","Cytotrophoblasts":"48.0","Respiratory ciliated cells":"76.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"fHDF\/TERT166":"70.2","SH-SY5Y":"215.4","THP-1":"100.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035054"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Actin filaments"],"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Actin filaments"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA035054":"AB_10603990"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.66e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.03e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.6","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"1.4","Tissue RNA - appendix [nTPM]":"1.6","Tissue RNA - basal ganglia [nTPM]":"0.9","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"2.2","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"1.3","Tissue RNA - cervix [nTPM]":"14.5","Tissue RNA - choroid plexus [nTPM]":"14.4","Tissue RNA - colon [nTPM]":"6.7","Tissue RNA - duodenum [nTPM]":"2.7","Tissue RNA - endometrium 1 [nTPM]":"1.9","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"3.2","Tissue RNA - fallopian tube [nTPM]":"10.5","Tissue RNA - gallbladder [nTPM]":"9.8","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"2.7","Tissue RNA - hypothalamus [nTPM]":"0.5","Tissue RNA - kidney [nTPM]":"0.8","Tissue RNA - liver [nTPM]":"0.6","Tissue RNA - lung [nTPM]":"7.6","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"1.9","Tissue RNA - ovary [nTPM]":"1.6","Tissue RNA - pancreas [nTPM]":"7.7","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.6","Tissue RNA - placenta [nTPM]":"10.6","Tissue RNA - pons [nTPM]":"0.7","Tissue RNA - prostate [nTPM]":"1.4","Tissue RNA - rectum [nTPM]":"6.4","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"2.5","Tissue RNA - seminal vesicle [nTPM]":"2.0","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"5.9","Tissue RNA - small intestine [nTPM]":"4.8","Tissue RNA - smooth muscle [nTPM]":"1.3","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"9.2","Tissue RNA - testis [nTPM]":"10.0","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"5.7","Tissue RNA - urinary bladder [nTPM]":"3.8","Tissue RNA - vagina [nTPM]":"12.6","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"5.2","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"1.8","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"13.3","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"46.0","Cell RNA - BJ hTERT+ [nTPM]":"41.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.1","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"18.7","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"70.2","Cell RNA - GAMG [nTPM]":"4.9","Cell RNA - HaCaT [nTPM]":"0.8","Cell RNA - HAP1 [nTPM]":"31.1","Cell RNA - HBEC3-KT [nTPM]":"9.5","Cell RNA - HBF TERT88 [nTPM]":"12.7","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"7.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"3.6","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"1.4","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"4.1","Cell RNA - hTCEpi [nTPM]":"17.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.4","Cell RNA - hTERT-HME1 [nTPM]":"9.9","Cell RNA - hTERT-RPE1 [nTPM]":"31.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.6","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"8.0","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"9.6","Cell RNA - NTERA-2 [nTPM]":"2.2","Cell RNA - OE19 [nTPM]":"36.4","Cell RNA - PC-3 [nTPM]":"2.9","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"38.7","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"7.0","Cell RNA - SCLC-21H [nTPM]":"5.1","Cell RNA - SH-SY5Y [nTPM]":"215.4","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"3.0","Cell RNA - SuSa [nTPM]":"30.9","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"100.6","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"19.2","Cell RNA - U-2 OS [nTPM]":"2.8","Cell RNA - U-2197 [nTPM]":"12.2","Cell RNA - U-251 MG [nTPM]":"9.1","Cell RNA - U-266\/70 [nTPM]":"1.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.0","Cell RNA - U-937 [nTPM]":"3.3","Cell RNA - WM-115 [nTPM]":"11.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.4","Brain RNA - basal ganglia [nTPM]":"0.9","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"1.3","Brain RNA - hippocampal formation [nTPM]":"2.7","Brain RNA - hypothalamus [nTPM]":"0.5","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"1.9","Brain RNA - pons [nTPM]":"0.7","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"34.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"48.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"26.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"9.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.8","Single Cell Type RNA - Endothelial cells [nTPM]":"0.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.3","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.5","Single Cell Type RNA - Fibroblasts [nTPM]":"7.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.6","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.7","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"4.2","Single Cell Type RNA - Late spermatids [nTPM]":"18.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.1","Single Cell Type RNA - Paneth cells [nTPM]":"12.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"76.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.9","Single Cell Type RNA - Spermatocytes [nTPM]":"10.1","Single Cell Type RNA - Spermatogonia [nTPM]":"13.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.9","Single Cell Type RNA - T-cells [nTPM]":"0.7","Single Cell Type RNA - Theca cells [nTPM]":"21.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.3","Single Cell Type RNA - Urothelial cells [nTPM]":"4.7"},{"Gene":"PRSS37","Gene synonym":[],"Ensembl":"ENSG00000165076","Gene description":"Serine protease 37","Uniprot":["A4D1T9"],"Chromosome":"7","Position":"141836300-141841487","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted secreted proteins"],"Biological process":["Fertilization"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"55","RNA tissue specific nTPM":{"testis":"41.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"138","RNA single cell type specific nTPM":{"Early spermatids":"612.8","Late spermatids":"325.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020541"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in male reproductive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA020541":"AB_1853004"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.7","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"41.3","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.7","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"612.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"325.7","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"3.4","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PRSS56","Gene synonym":[],"Ensembl":"ENSG00000237412","Gene description":"Serine protease 56","Uniprot":["P0CW18"],"Chromosome":"2","Position":"232520388-232525716","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Disease variant","Microphthalmia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"3.0","retina":"5.3","skeletal muscle":"9.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Early spermatids":"29.0","Muller glia cells":"45.8"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"cervical cancer":"1.2","colorectal cancer":"2.5","endometrial cancer":"1.4","melanoma":"2.1","urothelial cancer":"4.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Daudi":"1.0"},"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"10","RNA mouse brain regional specific nTPM":{"basal ganglia":"1.8","olfactory bulb":"4.2"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"olfactory bulb":"14.9"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 5: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"1.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"1.6","Tissue RNA - cerebral cortex [nTPM]":"3.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"3.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"2.9","Tissue RNA - midbrain [nTPM]":"1.3","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"5.3","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"9.7","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"1.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.5","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"1.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"1.2","Brain RNA - cerebellum [nTPM]":"1.6","Brain RNA - cerebral cortex [nTPM]":"3.0","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"3.0","Brain RNA - medulla oblongata [nTPM]":"2.9","Brain RNA - midbrain [nTPM]":"1.3","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"1.4","Brain RNA - white matter [nTPM]":"0.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"29.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"45.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"1.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PRTN3","Gene synonym":["ACPA","AGP7","C-ANCA","MBT","P29","PR-3"],"Ensembl":"ENSG00000196415","Gene description":"Proteinase 3","Uniprot":["P24158"],"Chromosome":"19","Position":"840999-848175","Protein class":["Candidate cardiovascular disease genes","Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Collagen degradation"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"55","RNA tissue specific nTPM":{"bone marrow":"2098.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"17","RNA single cell type specific nTPM":{"Erythroid cells":"26.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"stomach cancer":"1.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"neutrophil":"2.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"2.0"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"THP-1":"2054.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005938","CAB017558"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"390000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB017558":"AB_2172317","HPA005938":"AB_1855764"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-3"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.98e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.8","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.6","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.7","Tissue RNA - bone marrow [nTPM]":"2098.1","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"1.3","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"1.6","Tissue RNA - hippocampal formation [nTPM]":"0.6","Tissue RNA - hypothalamus [nTPM]":"0.4","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"2.8","Tissue RNA - lung [nTPM]":"11.7","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"1.3","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"1.6","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"1.3","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"38.2","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"7.1","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"1.2","Cell RNA - A549 [nTPM]":"0.6","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"5.5","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"343.6","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.8","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"2054.4","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"14.3","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"2.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"9.9","Brain RNA - amygdala [nTPM]":"0.6","Brain RNA - basal ganglia [nTPM]":"0.7","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"1.3","Brain RNA - hippocampal formation [nTPM]":"0.6","Brain RNA - hypothalamus [nTPM]":"0.4","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"26.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.9","Single Cell Type RNA - Fibroblasts [nTPM]":"0.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.5","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"1.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"PRUNE1","Gene synonym":["DRES-17","H-PRUNE","HTCD37","PRUNE"],"Ensembl":"ENSG00000143363","Gene description":"Prune exopolyphosphatase 1","Uniprot":["Q86TP1"],"Chromosome":"1","Position":"151008420-151035713","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Mental retardation","Neurodegeneration","Primary microcephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"13.0","Breast glandular cells":"9.8","Breast myoepithelial cells":"8.9","Collecting duct cells":"11.0","Granulosa cells":"8.9","Proximal tubular cells":"8.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-698":"169.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028411"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"41000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA028411":"AB_10603229"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.86e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.48e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.1","Tissue RNA - adrenal gland [nTPM]":"9.5","Tissue RNA - amygdala [nTPM]":"12.2","Tissue RNA - appendix [nTPM]":"7.7","Tissue RNA - basal ganglia [nTPM]":"12.1","Tissue RNA - bone marrow [nTPM]":"4.4","Tissue RNA - breast [nTPM]":"14.9","Tissue RNA - cerebellum [nTPM]":"16.1","Tissue RNA - cerebral cortex [nTPM]":"15.1","Tissue RNA - cervix [nTPM]":"15.0","Tissue RNA - choroid plexus [nTPM]":"12.4","Tissue RNA - colon [nTPM]":"14.8","Tissue RNA - duodenum [nTPM]":"12.5","Tissue RNA - endometrium 1 [nTPM]":"14.8","Tissue RNA - epididymis [nTPM]":"15.6","Tissue RNA - esophagus [nTPM]":"12.4","Tissue RNA - fallopian tube [nTPM]":"16.0","Tissue RNA - gallbladder [nTPM]":"9.2","Tissue RNA - heart muscle [nTPM]":"33.4","Tissue RNA - hippocampal formation [nTPM]":"12.4","Tissue RNA - hypothalamus [nTPM]":"12.6","Tissue RNA - kidney [nTPM]":"18.8","Tissue RNA - liver [nTPM]":"14.3","Tissue RNA - lung [nTPM]":"10.8","Tissue RNA - lymph node [nTPM]":"10.8","Tissue RNA - medulla oblongata [nTPM]":"12.0","Tissue RNA - midbrain [nTPM]":"12.5","Tissue RNA - ovary [nTPM]":"17.2","Tissue RNA - pancreas [nTPM]":"10.7","Tissue RNA - parathyroid gland [nTPM]":"20.9","Tissue RNA - pituitary gland [nTPM]":"12.6","Tissue RNA - placenta [nTPM]":"7.1","Tissue RNA - pons [nTPM]":"11.9","Tissue RNA - prostate [nTPM]":"12.2","Tissue RNA - rectum [nTPM]":"14.5","Tissue RNA - retina [nTPM]":"10.8","Tissue RNA - salivary gland [nTPM]":"13.2","Tissue RNA - seminal vesicle [nTPM]":"14.4","Tissue RNA - skeletal muscle [nTPM]":"29.4","Tissue RNA - skin 1 [nTPM]":"11.5","Tissue RNA - small intestine [nTPM]":"12.0","Tissue RNA - smooth muscle [nTPM]":"14.1","Tissue RNA - spinal cord [nTPM]":"11.9","Tissue RNA - spleen [nTPM]":"11.2","Tissue RNA - stomach 1 [nTPM]":"11.2","Tissue RNA - testis [nTPM]":"18.3","Tissue RNA - thalamus [nTPM]":"12.8","Tissue RNA - thymus [nTPM]":"16.2","Tissue RNA - thyroid gland [nTPM]":"32.5","Tissue RNA - tongue [nTPM]":"21.4","Tissue RNA - tonsil [nTPM]":"12.6","Tissue RNA - urinary bladder [nTPM]":"13.7","Tissue RNA - vagina [nTPM]":"11.9","Tissue RNA - white matter [nTPM]":"13.5","Cell RNA - A-431 [nTPM]":"11.0","Cell RNA - A549 [nTPM]":"11.6","Cell RNA - AF22 [nTPM]":"20.2","Cell RNA - AN3-CA [nTPM]":"19.3","Cell RNA - ASC diff [nTPM]":"24.3","Cell RNA - ASC TERT1 [nTPM]":"6.6","Cell RNA - BEWO [nTPM]":"10.9","Cell RNA - BJ [nTPM]":"5.1","Cell RNA - BJ hTERT+ [nTPM]":"11.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.4","Cell RNA - CACO-2 [nTPM]":"14.1","Cell RNA - CAPAN-2 [nTPM]":"13.0","Cell RNA - Daudi [nTPM]":"22.2","Cell RNA - EFO-21 [nTPM]":"21.7","Cell RNA - fHDF\/TERT166 [nTPM]":"6.9","Cell RNA - GAMG [nTPM]":"5.5","Cell RNA - HaCaT [nTPM]":"15.5","Cell RNA - HAP1 [nTPM]":"19.9","Cell RNA - HBEC3-KT [nTPM]":"13.4","Cell RNA - HBF TERT88 [nTPM]":"14.6","Cell RNA - HDLM-2 [nTPM]":"24.5","Cell RNA - HEK 293 [nTPM]":"22.6","Cell RNA - HEL [nTPM]":"26.6","Cell RNA - HeLa [nTPM]":"11.8","Cell RNA - Hep G2 [nTPM]":"20.4","Cell RNA - HHSteC [nTPM]":"13.5","Cell RNA - HL-60 [nTPM]":"17.5","Cell RNA - HMC-1 [nTPM]":"13.0","Cell RNA - HSkMC [nTPM]":"8.4","Cell RNA - hTCEpi [nTPM]":"24.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.2","Cell RNA - hTERT-HME1 [nTPM]":"9.5","Cell RNA - hTERT-RPE1 [nTPM]":"15.4","Cell RNA - HUVEC TERT2 [nTPM]":"9.2","Cell RNA - JURKAT [nTPM]":"29.4","Cell RNA - K-562 [nTPM]":"21.1","Cell RNA - Karpas-707 [nTPM]":"18.3","Cell RNA - LHCN-M2 [nTPM]":"8.9","Cell RNA - MCF7 [nTPM]":"26.2","Cell RNA - MOLT-4 [nTPM]":"27.2","Cell RNA - NB-4 [nTPM]":"14.1","Cell RNA - NTERA-2 [nTPM]":"18.7","Cell RNA - OE19 [nTPM]":"39.7","Cell RNA - PC-3 [nTPM]":"15.0","Cell RNA - REH [nTPM]":"24.2","Cell RNA - RH-30 [nTPM]":"12.8","Cell RNA - RPMI-8226 [nTPM]":"21.5","Cell RNA - RPTEC TERT1 [nTPM]":"13.4","Cell RNA - RT4 [nTPM]":"14.9","Cell RNA - SCLC-21H [nTPM]":"28.7","Cell RNA - SH-SY5Y [nTPM]":"23.5","Cell RNA - SiHa [nTPM]":"17.5","Cell RNA - SK-BR-3 [nTPM]":"23.5","Cell RNA - SK-MEL-30 [nTPM]":"16.1","Cell RNA - SuSa [nTPM]":"28.3","Cell RNA - T-47d [nTPM]":"32.6","Cell RNA - THP-1 [nTPM]":"25.7","Cell RNA - TIME [nTPM]":"6.3","Cell RNA - U-138 MG [nTPM]":"6.6","Cell RNA - U-2 OS [nTPM]":"7.8","Cell RNA - U-2197 [nTPM]":"7.5","Cell RNA - U-251 MG [nTPM]":"8.1","Cell RNA - U-266\/70 [nTPM]":"44.1","Cell RNA - U-266\/84 [nTPM]":"40.0","Cell RNA - U-698 [nTPM]":"169.1","Cell RNA - U-87 MG [nTPM]":"6.5","Cell RNA - U-937 [nTPM]":"13.0","Cell RNA - WM-115 [nTPM]":"16.9","Blood RNA - basophil [nTPM]":"19.1","Blood RNA - classical monocyte [nTPM]":"8.1","Blood RNA - eosinophil [nTPM]":"17.8","Blood RNA - gdT-cell [nTPM]":"16.4","Blood RNA - intermediate monocyte [nTPM]":"7.8","Blood RNA - MAIT T-cell [nTPM]":"19.8","Blood RNA - memory B-cell [nTPM]":"14.4","Blood RNA - memory CD4 T-cell [nTPM]":"18.1","Blood RNA - memory CD8 T-cell [nTPM]":"18.6","Blood RNA - myeloid DC [nTPM]":"11.9","Blood RNA - naive B-cell [nTPM]":"15.4","Blood RNA - naive CD4 T-cell [nTPM]":"21.7","Blood RNA - naive CD8 T-cell [nTPM]":"17.5","Blood RNA - neutrophil [nTPM]":"18.6","Blood RNA - NK-cell [nTPM]":"18.8","Blood RNA - non-classical monocyte [nTPM]":"12.2","Blood RNA - plasmacytoid DC [nTPM]":"6.4","Blood RNA - T-reg [nTPM]":"18.5","Blood RNA - total PBMC [nTPM]":"22.3","Brain RNA - amygdala [nTPM]":"12.2","Brain RNA - basal ganglia [nTPM]":"12.1","Brain RNA - cerebellum [nTPM]":"16.1","Brain RNA - cerebral cortex [nTPM]":"15.1","Brain RNA - hippocampal formation [nTPM]":"12.4","Brain RNA - hypothalamus [nTPM]":"12.6","Brain RNA - medulla oblongata [nTPM]":"12.0","Brain RNA - midbrain [nTPM]":"12.5","Brain RNA - pons [nTPM]":"11.9","Brain RNA - spinal cord [nTPM]":"11.9","Brain RNA - thalamus [nTPM]":"12.8","Brain RNA - white matter [nTPM]":"13.5","Single Cell Type RNA - Adipocytes [nTPM]":"4.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.1","Single Cell Type RNA - dendritic cells [nTPM]":"3.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.8","Single Cell Type RNA - Endothelial cells [nTPM]":"2.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.8","Single Cell Type RNA - Fibroblasts [nTPM]":"2.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"8.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"2.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.1","Single Cell Type RNA - T-cells [nTPM]":"2.8","Single Cell Type RNA - Theca cells [nTPM]":"4.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PSAP","Gene synonym":["GLBA","SAP1","SAP2"],"Ensembl":"ENSG00000197746","Gene description":"Prosaposin","Uniprot":["P07602"],"Chromosome":"10","Position":"71816298-71851325","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Lipid metabolism","Sphingolipid metabolism"],"Molecular function":null,"Disease involvement":["Disease variant","Gangliosidosis","Gaucher disease","Leukodystrophy","Metachromatic leukodystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"2792.8","Kupffer cells":"2427.0","Macrophages":"1916.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"11615.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"5104.0","hTERT-RPE1":"6978.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004426","CAB004647"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"88000000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB004647":"AB_425625","HPA004426":"AB_1079701"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.36e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Tissue RNA - adipose tissue [nTPM]":"1068.6","Tissue RNA - adrenal gland [nTPM]":"1192.2","Tissue RNA - amygdala [nTPM]":"831.4","Tissue RNA - appendix [nTPM]":"874.2","Tissue RNA - basal ganglia [nTPM]":"946.7","Tissue RNA - bone marrow [nTPM]":"834.2","Tissue RNA - breast [nTPM]":"683.8","Tissue RNA - cerebellum [nTPM]":"873.7","Tissue RNA - cerebral cortex [nTPM]":"831.7","Tissue RNA - cervix [nTPM]":"1073.9","Tissue RNA - choroid plexus [nTPM]":"1023.0","Tissue RNA - colon [nTPM]":"667.1","Tissue RNA - duodenum [nTPM]":"475.6","Tissue RNA - endometrium 1 [nTPM]":"879.3","Tissue RNA - epididymis [nTPM]":"951.2","Tissue RNA - esophagus [nTPM]":"605.5","Tissue RNA - fallopian tube [nTPM]":"724.7","Tissue RNA - gallbladder [nTPM]":"1115.6","Tissue RNA - heart muscle [nTPM]":"1413.3","Tissue RNA - hippocampal formation [nTPM]":"830.5","Tissue RNA - hypothalamus [nTPM]":"1081.8","Tissue RNA - kidney [nTPM]":"860.4","Tissue RNA - liver [nTPM]":"906.4","Tissue RNA - lung [nTPM]":"1118.6","Tissue RNA - lymph node [nTPM]":"956.1","Tissue RNA - medulla oblongata [nTPM]":"957.6","Tissue RNA - midbrain [nTPM]":"894.0","Tissue RNA - ovary [nTPM]":"1106.9","Tissue RNA - pancreas [nTPM]":"544.7","Tissue RNA - parathyroid gland [nTPM]":"1167.5","Tissue RNA - pituitary gland [nTPM]":"563.5","Tissue RNA - placenta [nTPM]":"869.3","Tissue RNA - pons [nTPM]":"885.3","Tissue RNA - prostate [nTPM]":"773.9","Tissue RNA - rectum [nTPM]":"625.5","Tissue RNA - retina [nTPM]":"665.2","Tissue RNA - salivary gland [nTPM]":"580.9","Tissue RNA - seminal vesicle [nTPM]":"936.8","Tissue RNA - skeletal muscle [nTPM]":"1409.5","Tissue RNA - skin 1 [nTPM]":"544.4","Tissue RNA - small intestine [nTPM]":"487.7","Tissue RNA - smooth muscle [nTPM]":"1138.6","Tissue RNA - spinal cord [nTPM]":"1025.9","Tissue RNA - spleen [nTPM]":"1045.9","Tissue RNA - stomach 1 [nTPM]":"664.0","Tissue RNA - testis [nTPM]":"489.1","Tissue RNA - thalamus [nTPM]":"1048.8","Tissue RNA - thymus [nTPM]":"672.3","Tissue RNA - thyroid gland [nTPM]":"875.9","Tissue RNA - tongue [nTPM]":"987.5","Tissue RNA - tonsil [nTPM]":"560.4","Tissue RNA - urinary bladder [nTPM]":"941.2","Tissue RNA - vagina [nTPM]":"578.3","Tissue RNA - white matter [nTPM]":"1325.1","Cell RNA - A-431 [nTPM]":"455.9","Cell RNA - A549 [nTPM]":"847.4","Cell RNA - AF22 [nTPM]":"540.4","Cell RNA - AN3-CA [nTPM]":"1121.0","Cell RNA - ASC diff [nTPM]":"5104.0","Cell RNA - ASC TERT1 [nTPM]":"2910.1","Cell RNA - BEWO [nTPM]":"1900.2","Cell RNA - BJ [nTPM]":"799.9","Cell RNA - BJ hTERT+ [nTPM]":"2368.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"620.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"735.9","Cell RNA - CACO-2 [nTPM]":"795.4","Cell RNA - CAPAN-2 [nTPM]":"1131.9","Cell RNA - Daudi [nTPM]":"245.6","Cell RNA - EFO-21 [nTPM]":"1608.1","Cell RNA - fHDF\/TERT166 [nTPM]":"1321.6","Cell RNA - GAMG [nTPM]":"1038.9","Cell RNA - HaCaT [nTPM]":"964.1","Cell RNA - HAP1 [nTPM]":"207.5","Cell RNA - HBEC3-KT [nTPM]":"659.1","Cell RNA - HBF TERT88 [nTPM]":"434.8","Cell RNA - HDLM-2 [nTPM]":"481.4","Cell RNA - HEK 293 [nTPM]":"381.8","Cell RNA - HEL [nTPM]":"288.9","Cell RNA - HeLa [nTPM]":"352.3","Cell RNA - Hep G2 [nTPM]":"459.6","Cell RNA - HHSteC [nTPM]":"1970.7","Cell RNA - HL-60 [nTPM]":"188.8","Cell RNA - HMC-1 [nTPM]":"1596.0","Cell RNA - HSkMC [nTPM]":"1871.8","Cell RNA - hTCEpi [nTPM]":"1479.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"625.7","Cell RNA - hTERT-HME1 [nTPM]":"1177.6","Cell RNA - hTERT-RPE1 [nTPM]":"6978.9","Cell RNA - HUVEC TERT2 [nTPM]":"1128.1","Cell RNA - JURKAT [nTPM]":"345.8","Cell RNA - K-562 [nTPM]":"420.5","Cell RNA - Karpas-707 [nTPM]":"1158.1","Cell RNA - LHCN-M2 [nTPM]":"777.0","Cell RNA - MCF7 [nTPM]":"294.9","Cell RNA - MOLT-4 [nTPM]":"843.8","Cell RNA - NB-4 [nTPM]":"290.1","Cell RNA - NTERA-2 [nTPM]":"249.5","Cell RNA - OE19 [nTPM]":"575.4","Cell RNA - PC-3 [nTPM]":"404.0","Cell RNA - REH [nTPM]":"172.9","Cell RNA - RH-30 [nTPM]":"301.3","Cell RNA - RPMI-8226 [nTPM]":"696.7","Cell RNA - RPTEC TERT1 [nTPM]":"730.3","Cell RNA - RT4 [nTPM]":"764.4","Cell RNA - SCLC-21H [nTPM]":"584.4","Cell RNA - SH-SY5Y [nTPM]":"515.8","Cell RNA - SiHa [nTPM]":"751.1","Cell RNA - SK-BR-3 [nTPM]":"2248.3","Cell RNA - SK-MEL-30 [nTPM]":"3122.2","Cell RNA - SuSa [nTPM]":"700.4","Cell RNA - T-47d [nTPM]":"454.4","Cell RNA - THP-1 [nTPM]":"431.1","Cell RNA - TIME [nTPM]":"1467.0","Cell RNA - U-138 MG [nTPM]":"861.8","Cell RNA - U-2 OS [nTPM]":"610.0","Cell RNA - U-2197 [nTPM]":"587.1","Cell RNA - U-251 MG [nTPM]":"670.5","Cell RNA - U-266\/70 [nTPM]":"1289.0","Cell RNA - U-266\/84 [nTPM]":"1038.7","Cell RNA - U-698 [nTPM]":"435.4","Cell RNA - U-87 MG [nTPM]":"1375.5","Cell RNA - U-937 [nTPM]":"374.4","Cell RNA - WM-115 [nTPM]":"650.0","Blood RNA - basophil [nTPM]":"863.2","Blood RNA - classical monocyte [nTPM]":"10095.9","Blood RNA - eosinophil [nTPM]":"1127.5","Blood RNA - gdT-cell [nTPM]":"424.2","Blood RNA - intermediate monocyte [nTPM]":"11615.6","Blood RNA - MAIT T-cell [nTPM]":"349.8","Blood RNA - memory B-cell [nTPM]":"466.7","Blood RNA - memory CD4 T-cell [nTPM]":"342.9","Blood RNA - memory CD8 T-cell [nTPM]":"368.8","Blood RNA - myeloid DC [nTPM]":"3481.1","Blood RNA - naive B-cell [nTPM]":"425.5","Blood RNA - naive CD4 T-cell [nTPM]":"370.1","Blood RNA - naive CD8 T-cell [nTPM]":"350.6","Blood RNA - neutrophil [nTPM]":"2890.4","Blood RNA - NK-cell [nTPM]":"365.8","Blood RNA - non-classical monocyte [nTPM]":"10148.2","Blood RNA - plasmacytoid DC [nTPM]":"1758.2","Blood RNA - T-reg [nTPM]":"422.8","Blood RNA - total PBMC [nTPM]":"15009.0","Brain RNA - amygdala [nTPM]":"831.4","Brain RNA - basal ganglia [nTPM]":"946.7","Brain RNA - cerebellum [nTPM]":"873.7","Brain RNA - cerebral cortex [nTPM]":"831.7","Brain RNA - hippocampal formation [nTPM]":"830.5","Brain RNA - hypothalamus [nTPM]":"1081.8","Brain RNA - medulla oblongata [nTPM]":"957.6","Brain RNA - midbrain [nTPM]":"894.0","Brain RNA - pons [nTPM]":"885.3","Brain RNA - spinal cord [nTPM]":"1025.9","Brain RNA - thalamus [nTPM]":"1048.8","Brain RNA - white matter [nTPM]":"1325.1","Single Cell Type RNA - Adipocytes [nTPM]":"263.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"253.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"339.0","Single Cell Type RNA - Astrocytes [nTPM]":"136.8","Single Cell Type RNA - B-cells [nTPM]":"173.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"228.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"253.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"487.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"108.1","Single Cell Type RNA - Bipolar cells [nTPM]":"193.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"254.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"158.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"664.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"253.1","Single Cell Type RNA - Club cells [nTPM]":"318.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"476.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"127.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"891.6","Single Cell Type RNA - dendritic cells [nTPM]":"260.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"434.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"70.5","Single Cell Type RNA - Ductal cells [nTPM]":"1043.6","Single Cell Type RNA - Early spermatids [nTPM]":"19.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"147.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"246.6","Single Cell Type RNA - Endothelial cells [nTPM]":"311.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"261.9","Single Cell Type RNA - Erythroid cells [nTPM]":"160.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"86.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"456.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"872.6","Single Cell Type RNA - Fibroblasts [nTPM]":"623.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"187.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"195.2","Single Cell Type RNA - granulocytes [nTPM]":"398.1","Single Cell Type RNA - Granulosa cells [nTPM]":"210.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"426.9","Single Cell Type RNA - Hepatocytes [nTPM]":"509.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"2792.8","Single Cell Type RNA - Horizontal cells [nTPM]":"333.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"93.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"242.2","Single Cell Type RNA - Ionocytes [nTPM]":"343.8","Single Cell Type RNA - Kupffer cells [nTPM]":"2427.0","Single Cell Type RNA - Langerhans cells [nTPM]":"779.7","Single Cell Type RNA - Late spermatids [nTPM]":"54.1","Single Cell Type RNA - Leydig cells [nTPM]":"458.6","Single Cell Type RNA - Macrophages [nTPM]":"1916.9","Single Cell Type RNA - Melanocytes [nTPM]":"663.5","Single Cell Type RNA - Microglial cells [nTPM]":"105.9","Single Cell Type RNA - monocytes [nTPM]":"1528.9","Single Cell Type RNA - Muller glia cells [nTPM]":"495.6","Single Cell Type RNA - NK-cells [nTPM]":"182.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"92.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"117.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"357.7","Single Cell Type RNA - Paneth cells [nTPM]":"298.3","Single Cell Type RNA - Peritubular cells [nTPM]":"551.8","Single Cell Type RNA - Plasma cells [nTPM]":"503.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"244.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"370.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"311.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"297.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"164.3","Single Cell Type RNA - Sertoli cells [nTPM]":"276.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"273.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"263.8","Single Cell Type RNA - Spermatocytes [nTPM]":"55.2","Single Cell Type RNA - Spermatogonia [nTPM]":"126.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"137.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"198.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1073.2","Single Cell Type RNA - T-cells [nTPM]":"138.9","Single Cell Type RNA - Theca cells [nTPM]":"624.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"228.3","Single Cell Type RNA - Urothelial cells [nTPM]":"223.9"},{"Gene":"PSAT1","Gene synonym":["PSA"],"Ensembl":"ENSG00000135069","Gene description":"Phosphoserine aminotransferase 1","Uniprot":["Q9Y617"],"Chromosome":"9","Position":"78297125-78330093","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Amino-acid biosynthesis","Serine biosynthesis"],"Molecular function":["Aminotransferase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"175.0","liver":"267.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"115.5","Glandular and luminal cells":"145.9","Hepatocytes":"161.7","Proximal tubular cells":"304.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"15.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"T-cells":"15.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTCEpi":"1170.1","SK-MEL-30":"752.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB014882","CAB040567","HPA042924"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2400000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB014882":null,"CAB040567":null,"HPA042924":"AB_2678223"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.62e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.00e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.8","Tissue RNA - adrenal gland [nTPM]":"65.8","Tissue RNA - amygdala [nTPM]":"123.3","Tissue RNA - appendix [nTPM]":"7.3","Tissue RNA - basal ganglia [nTPM]":"124.6","Tissue RNA - bone marrow [nTPM]":"2.0","Tissue RNA - breast [nTPM]":"5.1","Tissue RNA - cerebellum [nTPM]":"130.5","Tissue RNA - cerebral cortex [nTPM]":"175.0","Tissue RNA - cervix [nTPM]":"5.1","Tissue RNA - choroid plexus [nTPM]":"92.8","Tissue RNA - colon [nTPM]":"5.9","Tissue RNA - duodenum [nTPM]":"5.4","Tissue RNA - endometrium 1 [nTPM]":"4.3","Tissue RNA - epididymis [nTPM]":"61.6","Tissue RNA - esophagus [nTPM]":"33.2","Tissue RNA - fallopian tube [nTPM]":"34.7","Tissue RNA - gallbladder [nTPM]":"1.7","Tissue RNA - heart muscle [nTPM]":"2.7","Tissue RNA - hippocampal formation [nTPM]":"122.4","Tissue RNA - hypothalamus [nTPM]":"126.5","Tissue RNA - kidney [nTPM]":"136.7","Tissue RNA - liver [nTPM]":"267.9","Tissue RNA - lung [nTPM]":"5.1","Tissue RNA - lymph node [nTPM]":"9.3","Tissue RNA - medulla oblongata [nTPM]":"130.2","Tissue RNA - midbrain [nTPM]":"122.4","Tissue RNA - ovary [nTPM]":"5.6","Tissue RNA - pancreas [nTPM]":"129.1","Tissue RNA - parathyroid gland [nTPM]":"9.7","Tissue RNA - pituitary gland [nTPM]":"7.6","Tissue RNA - placenta [nTPM]":"3.0","Tissue RNA - pons [nTPM]":"129.9","Tissue RNA - prostate [nTPM]":"10.0","Tissue RNA - rectum [nTPM]":"5.5","Tissue RNA - retina [nTPM]":"6.2","Tissue RNA - salivary gland [nTPM]":"19.2","Tissue RNA - seminal vesicle [nTPM]":"4.0","Tissue RNA - skeletal muscle [nTPM]":"0.6","Tissue RNA - skin 1 [nTPM]":"57.2","Tissue RNA - small intestine [nTPM]":"4.5","Tissue RNA - smooth muscle [nTPM]":"3.3","Tissue RNA - spinal cord [nTPM]":"133.6","Tissue RNA - spleen [nTPM]":"6.0","Tissue RNA - stomach 1 [nTPM]":"19.4","Tissue RNA - testis [nTPM]":"10.4","Tissue RNA - thalamus [nTPM]":"120.3","Tissue RNA - thymus [nTPM]":"30.0","Tissue RNA - thyroid gland [nTPM]":"30.3","Tissue RNA - tongue [nTPM]":"0.5","Tissue RNA - tonsil [nTPM]":"12.4","Tissue RNA - urinary bladder [nTPM]":"7.3","Tissue RNA - vagina [nTPM]":"11.2","Tissue RNA - white matter [nTPM]":"161.6","Cell RNA - A-431 [nTPM]":"222.8","Cell RNA - A549 [nTPM]":"146.0","Cell RNA - AF22 [nTPM]":"121.1","Cell RNA - AN3-CA [nTPM]":"215.6","Cell RNA - ASC diff [nTPM]":"35.1","Cell RNA - ASC TERT1 [nTPM]":"41.2","Cell RNA - BEWO [nTPM]":"284.7","Cell RNA - BJ [nTPM]":"184.3","Cell RNA - BJ hTERT+ [nTPM]":"130.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"91.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"170.6","Cell RNA - CACO-2 [nTPM]":"38.2","Cell RNA - CAPAN-2 [nTPM]":"41.9","Cell RNA - Daudi [nTPM]":"143.2","Cell RNA - EFO-21 [nTPM]":"79.8","Cell RNA - fHDF\/TERT166 [nTPM]":"416.9","Cell RNA - GAMG [nTPM]":"82.9","Cell RNA - HaCaT [nTPM]":"215.3","Cell RNA - HAP1 [nTPM]":"209.1","Cell RNA - HBEC3-KT [nTPM]":"203.6","Cell RNA - HBF TERT88 [nTPM]":"136.4","Cell RNA - HDLM-2 [nTPM]":"141.2","Cell RNA - HEK 293 [nTPM]":"73.9","Cell RNA - HEL [nTPM]":"49.2","Cell RNA - HeLa [nTPM]":"60.8","Cell RNA - Hep G2 [nTPM]":"293.3","Cell RNA - HHSteC [nTPM]":"322.0","Cell RNA - HL-60 [nTPM]":"277.6","Cell RNA - HMC-1 [nTPM]":"84.6","Cell RNA - HSkMC [nTPM]":"131.1","Cell RNA - hTCEpi [nTPM]":"1170.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"122.0","Cell RNA - hTERT-HME1 [nTPM]":"322.9","Cell RNA - hTERT-RPE1 [nTPM]":"22.6","Cell RNA - HUVEC TERT2 [nTPM]":"85.0","Cell RNA - JURKAT [nTPM]":"548.3","Cell RNA - K-562 [nTPM]":"53.8","Cell RNA - Karpas-707 [nTPM]":"358.2","Cell RNA - LHCN-M2 [nTPM]":"77.1","Cell RNA - MCF7 [nTPM]":"83.2","Cell RNA - MOLT-4 [nTPM]":"95.8","Cell RNA - NB-4 [nTPM]":"44.3","Cell RNA - NTERA-2 [nTPM]":"278.2","Cell RNA - OE19 [nTPM]":"415.1","Cell RNA - PC-3 [nTPM]":"158.4","Cell RNA - REH [nTPM]":"46.5","Cell RNA - RH-30 [nTPM]":"78.6","Cell RNA - RPMI-8226 [nTPM]":"173.4","Cell RNA - RPTEC TERT1 [nTPM]":"126.6","Cell RNA - RT4 [nTPM]":"50.9","Cell RNA - SCLC-21H [nTPM]":"54.9","Cell RNA - SH-SY5Y [nTPM]":"127.0","Cell RNA - SiHa [nTPM]":"51.1","Cell RNA - SK-BR-3 [nTPM]":"87.7","Cell RNA - SK-MEL-30 [nTPM]":"752.3","Cell RNA - SuSa [nTPM]":"75.9","Cell RNA - T-47d [nTPM]":"42.0","Cell RNA - THP-1 [nTPM]":"344.1","Cell RNA - TIME [nTPM]":"19.9","Cell RNA - U-138 MG [nTPM]":"23.2","Cell RNA - U-2 OS [nTPM]":"73.5","Cell RNA - U-2197 [nTPM]":"85.9","Cell RNA - U-251 MG [nTPM]":"151.5","Cell RNA - U-266\/70 [nTPM]":"242.0","Cell RNA - U-266\/84 [nTPM]":"242.7","Cell RNA - U-698 [nTPM]":"0.8","Cell RNA - U-87 MG [nTPM]":"268.9","Cell RNA - U-937 [nTPM]":"215.6","Cell RNA - WM-115 [nTPM]":"112.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"5.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"5.9","Blood RNA - memory B-cell [nTPM]":"3.1","Blood RNA - memory CD4 T-cell [nTPM]":"5.0","Blood RNA - memory CD8 T-cell [nTPM]":"7.0","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"1.3","Blood RNA - naive CD4 T-cell [nTPM]":"8.1","Blood RNA - naive CD8 T-cell [nTPM]":"7.5","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"15.1","Blood RNA - total PBMC [nTPM]":"3.3","Brain RNA - amygdala [nTPM]":"123.3","Brain RNA - basal ganglia [nTPM]":"124.6","Brain RNA - cerebellum [nTPM]":"130.5","Brain RNA - cerebral cortex [nTPM]":"175.0","Brain RNA - hippocampal formation [nTPM]":"122.4","Brain RNA - hypothalamus [nTPM]":"126.5","Brain RNA - medulla oblongata [nTPM]":"130.2","Brain RNA - midbrain [nTPM]":"122.4","Brain RNA - pons [nTPM]":"129.9","Brain RNA - spinal cord [nTPM]":"133.6","Brain RNA - thalamus [nTPM]":"120.3","Brain RNA - white matter [nTPM]":"161.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"70.2","Single Cell Type RNA - B-cells [nTPM]":"11.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"41.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"115.5","Single Cell Type RNA - Bipolar cells [nTPM]":"0.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"4.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"32.0","Single Cell Type RNA - dendritic cells [nTPM]":"2.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"62.6","Single Cell Type RNA - Ductal cells [nTPM]":"11.5","Single Cell Type RNA - Early spermatids [nTPM]":"1.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"77.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.3","Single Cell Type RNA - Endothelial cells [nTPM]":"3.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"29.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"48.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.7","Single Cell Type RNA - Fibroblasts [nTPM]":"4.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"145.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"161.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.3","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.8","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"4.4","Single Cell Type RNA - Langerhans cells [nTPM]":"2.9","Single Cell Type RNA - Late spermatids [nTPM]":"3.8","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"3.4","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"3.8","Single Cell Type RNA - Muller glia cells [nTPM]":"26.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"48.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"78.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"29.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"304.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"33.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.6","Single Cell Type RNA - Spermatogonia [nTPM]":"3.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"35.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"50.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.3","Single Cell Type RNA - T-cells [nTPM]":"8.6","Single Cell Type RNA - Theca cells [nTPM]":"68.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.2","Single Cell Type RNA - Urothelial cells [nTPM]":"11.8"},{"Gene":"PSEN1","Gene synonym":["AD3","FAD","PS1","S182"],"Ensembl":"ENSG00000080815","Gene description":"Presenilin 1","Uniprot":["P49768"],"Chromosome":"14","Position":"73136418-73223691","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Cell adhesion","Notch signaling pathway"],"Molecular function":["Hydrolase","Protease"],"Disease involvement":["Alzheimer disease","Amyloidosis","Cancer-related genes","Cardiomyopathy","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Oligodendrocytes":"395.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB006844","HPA030760","HPA067496"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Cell Junctions"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Cell Junctions"],"Antibody RRID":{"CAB006844":null,"HPA030760":"AB_10696211","HPA067496":"AB_2685853"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.99e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.52e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Tissue RNA - adipose tissue [nTPM]":"25.1","Tissue RNA - adrenal gland [nTPM]":"22.6","Tissue RNA - amygdala [nTPM]":"44.3","Tissue RNA - appendix [nTPM]":"26.5","Tissue RNA - basal ganglia [nTPM]":"80.7","Tissue RNA - bone marrow [nTPM]":"39.6","Tissue RNA - breast [nTPM]":"28.2","Tissue RNA - cerebellum [nTPM]":"62.4","Tissue RNA - cerebral cortex [nTPM]":"56.0","Tissue RNA - cervix [nTPM]":"28.1","Tissue RNA - choroid plexus [nTPM]":"48.9","Tissue RNA - colon [nTPM]":"49.5","Tissue RNA - duodenum [nTPM]":"50.2","Tissue RNA - endometrium 1 [nTPM]":"25.3","Tissue RNA - epididymis [nTPM]":"26.9","Tissue RNA - esophagus [nTPM]":"35.2","Tissue RNA - fallopian tube [nTPM]":"22.9","Tissue RNA - gallbladder [nTPM]":"31.7","Tissue RNA - heart muscle [nTPM]":"18.0","Tissue RNA - hippocampal formation [nTPM]":"47.4","Tissue RNA - hypothalamus [nTPM]":"51.6","Tissue RNA - kidney [nTPM]":"35.5","Tissue RNA - liver [nTPM]":"31.9","Tissue RNA - lung [nTPM]":"32.1","Tissue RNA - lymph node [nTPM]":"22.4","Tissue RNA - medulla oblongata [nTPM]":"73.0","Tissue RNA - midbrain [nTPM]":"63.8","Tissue RNA - ovary [nTPM]":"22.0","Tissue RNA - pancreas [nTPM]":"22.9","Tissue RNA - parathyroid gland [nTPM]":"35.1","Tissue RNA - pituitary gland [nTPM]":"11.6","Tissue RNA - placenta [nTPM]":"43.1","Tissue RNA - pons [nTPM]":"71.5","Tissue RNA - prostate [nTPM]":"24.3","Tissue RNA - rectum [nTPM]":"46.3","Tissue RNA - retina [nTPM]":"23.4","Tissue RNA - salivary gland [nTPM]":"22.9","Tissue RNA - seminal vesicle [nTPM]":"23.4","Tissue RNA - skeletal muscle [nTPM]":"18.4","Tissue RNA - skin 1 [nTPM]":"38.2","Tissue RNA - small intestine [nTPM]":"49.0","Tissue RNA - smooth muscle [nTPM]":"27.1","Tissue RNA - spinal cord [nTPM]":"55.7","Tissue RNA - spleen [nTPM]":"22.6","Tissue RNA - stomach 1 [nTPM]":"31.0","Tissue RNA - testis [nTPM]":"32.5","Tissue RNA - thalamus [nTPM]":"60.8","Tissue RNA - thymus [nTPM]":"26.2","Tissue RNA - thyroid gland [nTPM]":"36.9","Tissue RNA - tongue [nTPM]":"23.3","Tissue RNA - tonsil [nTPM]":"30.7","Tissue RNA - urinary bladder [nTPM]":"35.0","Tissue RNA - vagina [nTPM]":"19.2","Tissue RNA - white matter [nTPM]":"119.1","Cell RNA - A-431 [nTPM]":"37.1","Cell RNA - A549 [nTPM]":"55.9","Cell RNA - AF22 [nTPM]":"50.6","Cell RNA - AN3-CA [nTPM]":"20.0","Cell RNA - ASC diff [nTPM]":"68.9","Cell RNA - ASC TERT1 [nTPM]":"49.9","Cell RNA - BEWO [nTPM]":"46.7","Cell RNA - BJ [nTPM]":"52.5","Cell RNA - BJ hTERT+ [nTPM]":"60.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"52.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"66.7","Cell RNA - CACO-2 [nTPM]":"69.9","Cell RNA - CAPAN-2 [nTPM]":"88.9","Cell RNA - Daudi [nTPM]":"23.7","Cell RNA - EFO-21 [nTPM]":"34.1","Cell RNA - fHDF\/TERT166 [nTPM]":"50.5","Cell RNA - GAMG [nTPM]":"43.0","Cell RNA - HaCaT [nTPM]":"94.9","Cell RNA - HAP1 [nTPM]":"43.2","Cell RNA - HBEC3-KT [nTPM]":"40.1","Cell RNA - HBF TERT88 [nTPM]":"57.3","Cell RNA - HDLM-2 [nTPM]":"54.6","Cell RNA - HEK 293 [nTPM]":"26.7","Cell RNA - HEL [nTPM]":"27.1","Cell RNA - HeLa [nTPM]":"35.1","Cell RNA - Hep G2 [nTPM]":"34.4","Cell RNA - HHSteC [nTPM]":"63.8","Cell RNA - HL-60 [nTPM]":"27.7","Cell RNA - HMC-1 [nTPM]":"50.7","Cell RNA - HSkMC [nTPM]":"50.4","Cell RNA - hTCEpi [nTPM]":"71.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"44.3","Cell RNA - hTERT-HME1 [nTPM]":"54.4","Cell RNA - hTERT-RPE1 [nTPM]":"48.5","Cell RNA - HUVEC TERT2 [nTPM]":"43.2","Cell RNA - JURKAT [nTPM]":"26.2","Cell RNA - K-562 [nTPM]":"31.0","Cell RNA - Karpas-707 [nTPM]":"46.6","Cell RNA - LHCN-M2 [nTPM]":"50.0","Cell RNA - MCF7 [nTPM]":"72.8","Cell RNA - MOLT-4 [nTPM]":"21.0","Cell RNA - NB-4 [nTPM]":"35.7","Cell RNA - NTERA-2 [nTPM]":"22.0","Cell RNA - OE19 [nTPM]":"64.5","Cell RNA - PC-3 [nTPM]":"40.4","Cell RNA - REH [nTPM]":"26.4","Cell RNA - RH-30 [nTPM]":"42.7","Cell RNA - RPMI-8226 [nTPM]":"30.2","Cell RNA - RPTEC TERT1 [nTPM]":"73.7","Cell RNA - RT4 [nTPM]":"76.5","Cell RNA - SCLC-21H [nTPM]":"28.1","Cell RNA - SH-SY5Y [nTPM]":"38.3","Cell RNA - SiHa [nTPM]":"57.4","Cell RNA - SK-BR-3 [nTPM]":"53.0","Cell RNA - SK-MEL-30 [nTPM]":"47.1","Cell RNA - SuSa [nTPM]":"45.4","Cell RNA - T-47d [nTPM]":"66.3","Cell RNA - THP-1 [nTPM]":"60.7","Cell RNA - TIME [nTPM]":"45.7","Cell RNA - U-138 MG [nTPM]":"53.1","Cell RNA - U-2 OS [nTPM]":"43.5","Cell RNA - U-2197 [nTPM]":"44.1","Cell RNA - U-251 MG [nTPM]":"25.3","Cell RNA - U-266\/70 [nTPM]":"30.3","Cell RNA - U-266\/84 [nTPM]":"47.9","Cell RNA - U-698 [nTPM]":"23.7","Cell RNA - U-87 MG [nTPM]":"44.9","Cell RNA - U-937 [nTPM]":"32.8","Cell RNA - WM-115 [nTPM]":"33.3","Blood RNA - basophil [nTPM]":"126.8","Blood RNA - classical monocyte [nTPM]":"94.5","Blood RNA - eosinophil [nTPM]":"96.3","Blood RNA - gdT-cell [nTPM]":"23.1","Blood RNA - intermediate monocyte [nTPM]":"106.0","Blood RNA - MAIT T-cell [nTPM]":"22.6","Blood RNA - memory B-cell [nTPM]":"23.1","Blood RNA - memory CD4 T-cell [nTPM]":"22.3","Blood RNA - memory CD8 T-cell [nTPM]":"19.0","Blood RNA - myeloid DC [nTPM]":"83.4","Blood RNA - naive B-cell [nTPM]":"31.8","Blood RNA - naive CD4 T-cell [nTPM]":"20.7","Blood RNA - naive CD8 T-cell [nTPM]":"20.1","Blood RNA - neutrophil [nTPM]":"129.3","Blood RNA - NK-cell [nTPM]":"42.8","Blood RNA - non-classical monocyte [nTPM]":"125.0","Blood RNA - plasmacytoid DC [nTPM]":"43.6","Blood RNA - T-reg [nTPM]":"37.0","Blood RNA - total PBMC [nTPM]":"70.3","Brain RNA - amygdala [nTPM]":"44.3","Brain RNA - basal ganglia [nTPM]":"80.7","Brain RNA - cerebellum [nTPM]":"62.4","Brain RNA - cerebral cortex [nTPM]":"56.0","Brain RNA - hippocampal formation [nTPM]":"47.4","Brain RNA - hypothalamus [nTPM]":"51.6","Brain RNA - medulla oblongata [nTPM]":"73.0","Brain RNA - midbrain [nTPM]":"63.8","Brain RNA - pons [nTPM]":"71.5","Brain RNA - spinal cord [nTPM]":"55.7","Brain RNA - thalamus [nTPM]":"60.8","Brain RNA - white matter [nTPM]":"119.1","Single Cell Type RNA - Adipocytes [nTPM]":"22.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"30.5","Single Cell Type RNA - Astrocytes [nTPM]":"35.9","Single Cell Type RNA - B-cells [nTPM]":"25.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"28.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"24.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.0","Single Cell Type RNA - Bipolar cells [nTPM]":"17.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"30.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.1","Single Cell Type RNA - dendritic cells [nTPM]":"30.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"79.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"27.1","Single Cell Type RNA - Early spermatids [nTPM]":"22.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"26.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.4","Single Cell Type RNA - Endothelial cells [nTPM]":"22.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.2","Single Cell Type RNA - Erythroid cells [nTPM]":"12.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"38.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"29.2","Single Cell Type RNA - Fibroblasts [nTPM]":"23.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"47.4","Single Cell Type RNA - granulocytes [nTPM]":"18.3","Single Cell Type RNA - Granulosa cells [nTPM]":"29.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.7","Single Cell Type RNA - Hepatocytes [nTPM]":"24.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.5","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"40.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"39.5","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"50.5","Single Cell Type RNA - Langerhans cells [nTPM]":"40.8","Single Cell Type RNA - Late spermatids [nTPM]":"12.9","Single Cell Type RNA - Leydig cells [nTPM]":"16.4","Single Cell Type RNA - Macrophages [nTPM]":"52.3","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"39.4","Single Cell Type RNA - monocytes [nTPM]":"51.8","Single Cell Type RNA - Muller glia cells [nTPM]":"13.8","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"48.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"395.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"38.2","Single Cell Type RNA - Paneth cells [nTPM]":"58.8","Single Cell Type RNA - Peritubular cells [nTPM]":"15.4","Single Cell Type RNA - Plasma cells [nTPM]":"23.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"38.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"76.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"28.0","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.0","Single Cell Type RNA - Spermatocytes [nTPM]":"40.2","Single Cell Type RNA - Spermatogonia [nTPM]":"14.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"33.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"49.9","Single Cell Type RNA - T-cells [nTPM]":"21.6","Single Cell Type RNA - Theca cells [nTPM]":"18.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"41.3","Single Cell Type RNA - Urothelial cells [nTPM]":"51.5"},{"Gene":"PSEN2","Gene synonym":["AD3L","AD4","PS2","STM2"],"Ensembl":"ENSG00000143801","Gene description":"Presenilin 2","Uniprot":["P49810"],"Chromosome":"1","Position":"226870184-226927726","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Notch signaling pathway"],"Molecular function":["Hydrolase","Protease"],"Disease involvement":["Alzheimer disease","Amyloidosis","Cardiomyopathy","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ionocytes":"36.7","Syncytiotrophoblasts":"45.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.53e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Tissue RNA - adipose tissue [nTPM]":"11.2","Tissue RNA - adrenal gland [nTPM]":"19.8","Tissue RNA - amygdala [nTPM]":"9.7","Tissue RNA - appendix [nTPM]":"7.5","Tissue RNA - basal ganglia [nTPM]":"9.8","Tissue RNA - bone marrow [nTPM]":"1.6","Tissue RNA - breast [nTPM]":"10.6","Tissue RNA - cerebellum [nTPM]":"12.5","Tissue RNA - cerebral cortex [nTPM]":"10.7","Tissue RNA - cervix [nTPM]":"9.7","Tissue RNA - choroid plexus [nTPM]":"10.7","Tissue RNA - colon [nTPM]":"15.2","Tissue RNA - duodenum [nTPM]":"10.5","Tissue RNA - endometrium 1 [nTPM]":"15.9","Tissue RNA - epididymis [nTPM]":"9.0","Tissue RNA - esophagus [nTPM]":"10.3","Tissue RNA - fallopian tube [nTPM]":"13.4","Tissue RNA - gallbladder [nTPM]":"8.3","Tissue RNA - heart muscle [nTPM]":"14.0","Tissue RNA - hippocampal formation [nTPM]":"9.4","Tissue RNA - hypothalamus [nTPM]":"10.6","Tissue RNA - kidney [nTPM]":"13.5","Tissue RNA - liver [nTPM]":"12.6","Tissue RNA - lung [nTPM]":"11.5","Tissue RNA - lymph node [nTPM]":"8.0","Tissue RNA - medulla oblongata [nTPM]":"9.8","Tissue RNA - midbrain [nTPM]":"10.9","Tissue RNA - ovary [nTPM]":"12.8","Tissue RNA - pancreas [nTPM]":"45.5","Tissue RNA - parathyroid gland [nTPM]":"18.1","Tissue RNA - pituitary gland [nTPM]":"17.1","Tissue RNA - placenta [nTPM]":"9.0","Tissue RNA - pons [nTPM]":"10.8","Tissue RNA - prostate [nTPM]":"14.9","Tissue RNA - rectum [nTPM]":"8.1","Tissue RNA - retina [nTPM]":"7.4","Tissue RNA - salivary gland [nTPM]":"13.0","Tissue RNA - seminal vesicle [nTPM]":"13.6","Tissue RNA - skeletal muscle [nTPM]":"26.5","Tissue RNA - skin 1 [nTPM]":"10.1","Tissue RNA - small intestine [nTPM]":"13.8","Tissue RNA - smooth muscle [nTPM]":"10.4","Tissue RNA - spinal cord [nTPM]":"8.5","Tissue RNA - spleen [nTPM]":"15.6","Tissue RNA - stomach 1 [nTPM]":"11.5","Tissue RNA - testis [nTPM]":"13.5","Tissue RNA - thalamus [nTPM]":"10.7","Tissue RNA - thymus [nTPM]":"3.3","Tissue RNA - thyroid gland [nTPM]":"9.5","Tissue RNA - tongue [nTPM]":"16.7","Tissue RNA - tonsil [nTPM]":"5.0","Tissue RNA - urinary bladder [nTPM]":"13.5","Tissue RNA - vagina [nTPM]":"9.7","Tissue RNA - white matter [nTPM]":"9.7","Cell RNA - A-431 [nTPM]":"14.1","Cell RNA - A549 [nTPM]":"24.5","Cell RNA - AF22 [nTPM]":"7.2","Cell RNA - AN3-CA [nTPM]":"21.9","Cell RNA - ASC diff [nTPM]":"10.0","Cell RNA - ASC TERT1 [nTPM]":"3.5","Cell RNA - BEWO [nTPM]":"10.2","Cell RNA - BJ [nTPM]":"12.4","Cell RNA - BJ hTERT+ [nTPM]":"26.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.9","Cell RNA - CACO-2 [nTPM]":"13.8","Cell RNA - CAPAN-2 [nTPM]":"21.5","Cell RNA - Daudi [nTPM]":"1.0","Cell RNA - EFO-21 [nTPM]":"17.0","Cell RNA - fHDF\/TERT166 [nTPM]":"16.8","Cell RNA - GAMG [nTPM]":"10.5","Cell RNA - HaCaT [nTPM]":"7.9","Cell RNA - HAP1 [nTPM]":"12.1","Cell RNA - HBEC3-KT [nTPM]":"11.9","Cell RNA - HBF TERT88 [nTPM]":"6.7","Cell RNA - HDLM-2 [nTPM]":"13.6","Cell RNA - HEK 293 [nTPM]":"20.7","Cell RNA - HEL [nTPM]":"8.7","Cell RNA - HeLa [nTPM]":"10.5","Cell RNA - Hep G2 [nTPM]":"12.0","Cell RNA - HHSteC [nTPM]":"15.4","Cell RNA - HL-60 [nTPM]":"7.5","Cell RNA - HMC-1 [nTPM]":"15.7","Cell RNA - HSkMC [nTPM]":"9.1","Cell RNA - hTCEpi [nTPM]":"13.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.9","Cell RNA - hTERT-HME1 [nTPM]":"10.4","Cell RNA - hTERT-RPE1 [nTPM]":"11.2","Cell RNA - HUVEC TERT2 [nTPM]":"6.9","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"18.1","Cell RNA - Karpas-707 [nTPM]":"6.4","Cell RNA - LHCN-M2 [nTPM]":"10.0","Cell RNA - MCF7 [nTPM]":"14.7","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"8.2","Cell RNA - NTERA-2 [nTPM]":"20.5","Cell RNA - OE19 [nTPM]":"22.0","Cell RNA - PC-3 [nTPM]":"16.0","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"22.6","Cell RNA - RPMI-8226 [nTPM]":"26.4","Cell RNA - RPTEC TERT1 [nTPM]":"15.9","Cell RNA - RT4 [nTPM]":"13.4","Cell RNA - SCLC-21H [nTPM]":"11.3","Cell RNA - SH-SY5Y [nTPM]":"18.3","Cell RNA - SiHa [nTPM]":"9.7","Cell RNA - SK-BR-3 [nTPM]":"30.6","Cell RNA - SK-MEL-30 [nTPM]":"51.6","Cell RNA - SuSa [nTPM]":"18.4","Cell RNA - T-47d [nTPM]":"26.5","Cell RNA - THP-1 [nTPM]":"13.1","Cell RNA - TIME [nTPM]":"8.5","Cell RNA - U-138 MG [nTPM]":"11.2","Cell RNA - U-2 OS [nTPM]":"8.9","Cell RNA - U-2197 [nTPM]":"9.9","Cell RNA - U-251 MG [nTPM]":"15.2","Cell RNA - U-266\/70 [nTPM]":"25.6","Cell RNA - U-266\/84 [nTPM]":"45.0","Cell RNA - U-698 [nTPM]":"0.9","Cell RNA - U-87 MG [nTPM]":"21.5","Cell RNA - U-937 [nTPM]":"2.5","Cell RNA - WM-115 [nTPM]":"15.7","Blood RNA - basophil [nTPM]":"37.4","Blood RNA - classical monocyte [nTPM]":"8.7","Blood RNA - eosinophil [nTPM]":"18.4","Blood RNA - gdT-cell [nTPM]":"4.5","Blood RNA - intermediate monocyte [nTPM]":"9.7","Blood RNA - MAIT T-cell [nTPM]":"5.1","Blood RNA - memory B-cell [nTPM]":"7.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"4.6","Blood RNA - myeloid DC [nTPM]":"11.4","Blood RNA - naive B-cell [nTPM]":"3.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"2.0","Blood RNA - neutrophil [nTPM]":"1.6","Blood RNA - NK-cell [nTPM]":"20.0","Blood RNA - non-classical monocyte [nTPM]":"30.2","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"2.4","Blood RNA - total PBMC [nTPM]":"5.2","Brain RNA - amygdala [nTPM]":"9.7","Brain RNA - basal ganglia [nTPM]":"9.8","Brain RNA - cerebellum [nTPM]":"12.5","Brain RNA - cerebral cortex [nTPM]":"10.7","Brain RNA - hippocampal formation [nTPM]":"9.4","Brain RNA - hypothalamus [nTPM]":"10.6","Brain RNA - medulla oblongata [nTPM]":"9.8","Brain RNA - midbrain [nTPM]":"10.9","Brain RNA - pons [nTPM]":"10.8","Brain RNA - spinal cord [nTPM]":"8.5","Brain RNA - thalamus [nTPM]":"10.7","Brain RNA - white matter [nTPM]":"9.7","Single Cell Type RNA - Adipocytes [nTPM]":"11.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.8","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"3.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"6.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"4.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.9","Single Cell Type RNA - dendritic cells [nTPM]":"1.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"13.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.0","Single Cell Type RNA - Endothelial cells [nTPM]":"10.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"6.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.1","Single Cell Type RNA - Fibroblasts [nTPM]":"5.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.2","Single Cell Type RNA - granulocytes [nTPM]":"14.5","Single Cell Type RNA - Granulosa cells [nTPM]":"10.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.2","Single Cell Type RNA - Hepatocytes [nTPM]":"8.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.2","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.1","Single Cell Type RNA - Ionocytes [nTPM]":"36.7","Single Cell Type RNA - Kupffer cells [nTPM]":"7.2","Single Cell Type RNA - Langerhans cells [nTPM]":"6.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"8.2","Single Cell Type RNA - Melanocytes [nTPM]":"33.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"18.9","Single Cell Type RNA - Muller glia cells [nTPM]":"21.2","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.2","Single Cell Type RNA - Paneth cells [nTPM]":"7.8","Single Cell Type RNA - Peritubular cells [nTPM]":"13.2","Single Cell Type RNA - Plasma cells [nTPM]":"9.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.6","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"6.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"45.8","Single Cell Type RNA - T-cells [nTPM]":"2.9","Single Cell Type RNA - Theca cells [nTPM]":"6.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.3","Single Cell Type RNA - Urothelial cells [nTPM]":"4.6"},{"Gene":"PSMB4","Gene synonym":["HN3","PROS26"],"Ensembl":"ENSG00000159377","Gene description":"Proteasome 20S subunit beta 4","Uniprot":["P28070"],"Chromosome":"1","Position":"151399560-151401937","Protein class":["Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Host-virus interaction"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006700","HPA073499"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"HPA006700":"AB_1079704","HPA073499":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.45e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.90e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"},"Tissue RNA - adipose tissue [nTPM]":"189.5","Tissue RNA - adrenal gland [nTPM]":"242.7","Tissue RNA - amygdala [nTPM]":"200.2","Tissue RNA - appendix [nTPM]":"156.7","Tissue RNA - basal ganglia [nTPM]":"202.1","Tissue RNA - bone marrow [nTPM]":"172.9","Tissue RNA - breast [nTPM]":"174.2","Tissue RNA - cerebellum [nTPM]":"210.6","Tissue RNA - cerebral cortex [nTPM]":"212.4","Tissue RNA - cervix [nTPM]":"167.0","Tissue RNA - choroid plexus [nTPM]":"201.9","Tissue RNA - colon [nTPM]":"194.3","Tissue RNA - duodenum [nTPM]":"150.0","Tissue RNA - endometrium 1 [nTPM]":"195.5","Tissue RNA - epididymis [nTPM]":"225.6","Tissue RNA - esophagus [nTPM]":"170.4","Tissue RNA - fallopian tube [nTPM]":"178.3","Tissue RNA - gallbladder [nTPM]":"139.1","Tissue RNA - heart muscle [nTPM]":"241.8","Tissue RNA - hippocampal formation [nTPM]":"201.7","Tissue RNA - hypothalamus [nTPM]":"212.9","Tissue RNA - kidney [nTPM]":"196.6","Tissue RNA - liver [nTPM]":"269.5","Tissue RNA - lung [nTPM]":"143.2","Tissue RNA - lymph node [nTPM]":"214.0","Tissue RNA - medulla oblongata [nTPM]":"206.8","Tissue RNA - midbrain [nTPM]":"203.9","Tissue RNA - ovary [nTPM]":"179.5","Tissue RNA - pancreas [nTPM]":"164.0","Tissue RNA - parathyroid gland [nTPM]":"218.6","Tissue RNA - pituitary gland [nTPM]":"168.0","Tissue RNA - placenta [nTPM]":"187.1","Tissue RNA - pons [nTPM]":"211.7","Tissue RNA - prostate [nTPM]":"162.4","Tissue RNA - rectum [nTPM]":"166.4","Tissue RNA - retina [nTPM]":"94.3","Tissue RNA - salivary gland [nTPM]":"169.6","Tissue RNA - seminal vesicle [nTPM]":"190.6","Tissue RNA - skeletal muscle [nTPM]":"299.1","Tissue RNA - skin 1 [nTPM]":"186.6","Tissue RNA - small intestine [nTPM]":"152.8","Tissue RNA - smooth muscle [nTPM]":"191.7","Tissue RNA - spinal cord [nTPM]":"210.5","Tissue RNA - spleen [nTPM]":"173.8","Tissue RNA - stomach 1 [nTPM]":"171.8","Tissue RNA - testis [nTPM]":"69.0","Tissue RNA - thalamus [nTPM]":"205.8","Tissue RNA - thymus [nTPM]":"233.5","Tissue RNA - thyroid gland [nTPM]":"156.1","Tissue RNA - tongue [nTPM]":"237.5","Tissue RNA - tonsil [nTPM]":"235.4","Tissue RNA - urinary bladder [nTPM]":"196.7","Tissue RNA - vagina [nTPM]":"151.3","Tissue RNA - white matter [nTPM]":"218.4","Cell RNA - A-431 [nTPM]":"428.3","Cell RNA - A549 [nTPM]":"451.9","Cell RNA - AF22 [nTPM]":"373.0","Cell RNA - AN3-CA [nTPM]":"447.8","Cell RNA - ASC diff [nTPM]":"412.9","Cell RNA - ASC TERT1 [nTPM]":"392.3","Cell RNA - BEWO [nTPM]":"507.8","Cell RNA - BJ [nTPM]":"247.6","Cell RNA - BJ hTERT+ [nTPM]":"549.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"719.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"503.1","Cell RNA - CACO-2 [nTPM]":"608.6","Cell RNA - CAPAN-2 [nTPM]":"569.5","Cell RNA - Daudi [nTPM]":"384.1","Cell RNA - EFO-21 [nTPM]":"730.7","Cell RNA - fHDF\/TERT166 [nTPM]":"424.3","Cell RNA - GAMG [nTPM]":"379.1","Cell RNA - HaCaT [nTPM]":"419.7","Cell RNA - HAP1 [nTPM]":"383.2","Cell RNA - HBEC3-KT [nTPM]":"472.7","Cell RNA - HBF TERT88 [nTPM]":"407.6","Cell RNA - HDLM-2 [nTPM]":"535.6","Cell RNA - HEK 293 [nTPM]":"391.1","Cell RNA - HEL [nTPM]":"268.6","Cell RNA - HeLa [nTPM]":"320.8","Cell RNA - Hep G2 [nTPM]":"463.3","Cell RNA - HHSteC [nTPM]":"444.4","Cell RNA - HL-60 [nTPM]":"377.0","Cell RNA - HMC-1 [nTPM]":"355.7","Cell RNA - HSkMC [nTPM]":"431.7","Cell RNA - hTCEpi [nTPM]":"444.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"672.5","Cell RNA - hTERT-HME1 [nTPM]":"276.2","Cell RNA - hTERT-RPE1 [nTPM]":"364.8","Cell RNA - HUVEC TERT2 [nTPM]":"506.1","Cell RNA - JURKAT [nTPM]":"419.1","Cell RNA - K-562 [nTPM]":"434.3","Cell RNA - Karpas-707 [nTPM]":"740.0","Cell RNA - LHCN-M2 [nTPM]":"512.7","Cell RNA - MCF7 [nTPM]":"1174.2","Cell RNA - MOLT-4 [nTPM]":"463.5","Cell RNA - NB-4 [nTPM]":"452.0","Cell RNA - NTERA-2 [nTPM]":"952.8","Cell RNA - OE19 [nTPM]":"638.6","Cell RNA - PC-3 [nTPM]":"576.2","Cell RNA - REH [nTPM]":"433.8","Cell RNA - RH-30 [nTPM]":"266.9","Cell RNA - RPMI-8226 [nTPM]":"688.2","Cell RNA - RPTEC TERT1 [nTPM]":"594.4","Cell RNA - RT4 [nTPM]":"354.2","Cell RNA - SCLC-21H [nTPM]":"408.6","Cell RNA - SH-SY5Y [nTPM]":"488.0","Cell RNA - SiHa [nTPM]":"283.6","Cell RNA - SK-BR-3 [nTPM]":"626.5","Cell RNA - SK-MEL-30 [nTPM]":"879.8","Cell RNA - SuSa [nTPM]":"459.1","Cell RNA - T-47d [nTPM]":"564.1","Cell RNA - THP-1 [nTPM]":"594.6","Cell RNA - TIME [nTPM]":"320.7","Cell RNA - U-138 MG [nTPM]":"310.4","Cell RNA - U-2 OS [nTPM]":"326.1","Cell RNA - U-2197 [nTPM]":"333.8","Cell RNA - U-251 MG [nTPM]":"557.0","Cell RNA - U-266\/70 [nTPM]":"726.9","Cell RNA - U-266\/84 [nTPM]":"902.5","Cell RNA - U-698 [nTPM]":"769.1","Cell RNA - U-87 MG [nTPM]":"459.5","Cell RNA - U-937 [nTPM]":"337.8","Cell RNA - WM-115 [nTPM]":"667.8","Blood RNA - basophil [nTPM]":"291.8","Blood RNA - classical monocyte [nTPM]":"343.4","Blood RNA - eosinophil [nTPM]":"227.0","Blood RNA - gdT-cell [nTPM]":"265.0","Blood RNA - intermediate monocyte [nTPM]":"342.2","Blood RNA - MAIT T-cell [nTPM]":"314.8","Blood RNA - memory B-cell [nTPM]":"293.6","Blood RNA - memory CD4 T-cell [nTPM]":"303.7","Blood RNA - memory CD8 T-cell [nTPM]":"301.0","Blood RNA - myeloid DC [nTPM]":"421.7","Blood RNA - naive B-cell [nTPM]":"257.5","Blood RNA - naive CD4 T-cell [nTPM]":"260.4","Blood RNA - naive CD8 T-cell [nTPM]":"272.8","Blood RNA - neutrophil [nTPM]":"251.5","Blood RNA - NK-cell [nTPM]":"347.3","Blood RNA - non-classical monocyte [nTPM]":"270.5","Blood RNA - plasmacytoid DC [nTPM]":"468.1","Blood RNA - T-reg [nTPM]":"405.1","Blood RNA - total PBMC [nTPM]":"395.2","Brain RNA - amygdala [nTPM]":"200.2","Brain RNA - basal ganglia [nTPM]":"202.1","Brain RNA - cerebellum [nTPM]":"210.6","Brain RNA - cerebral cortex [nTPM]":"212.4","Brain RNA - hippocampal formation [nTPM]":"201.7","Brain RNA - hypothalamus [nTPM]":"212.9","Brain RNA - medulla oblongata [nTPM]":"206.8","Brain RNA - midbrain [nTPM]":"203.9","Brain RNA - pons [nTPM]":"211.7","Brain RNA - spinal cord [nTPM]":"210.5","Brain RNA - thalamus [nTPM]":"205.8","Brain RNA - white matter [nTPM]":"218.4","Single Cell Type RNA - Adipocytes [nTPM]":"72.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"153.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"127.4","Single Cell Type RNA - Astrocytes [nTPM]":"10.1","Single Cell Type RNA - B-cells [nTPM]":"82.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"76.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"81.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"131.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"82.0","Single Cell Type RNA - Bipolar cells [nTPM]":"56.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"62.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"71.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"128.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"68.6","Single Cell Type RNA - Club cells [nTPM]":"123.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"71.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"209.8","Single Cell Type RNA - dendritic cells [nTPM]":"79.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"87.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"103.7","Single Cell Type RNA - Ductal cells [nTPM]":"127.9","Single Cell Type RNA - Early spermatids [nTPM]":"16.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"118.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"107.5","Single Cell Type RNA - Endothelial cells [nTPM]":"97.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"66.4","Single Cell Type RNA - Erythroid cells [nTPM]":"87.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"195.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"146.7","Single Cell Type RNA - Fibroblasts [nTPM]":"91.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"47.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"110.0","Single Cell Type RNA - granulocytes [nTPM]":"111.1","Single Cell Type RNA - Granulosa cells [nTPM]":"81.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"92.8","Single Cell Type RNA - Hepatocytes [nTPM]":"151.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"125.0","Single Cell Type RNA - Horizontal cells [nTPM]":"48.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"80.5","Single Cell Type RNA - Ionocytes [nTPM]":"89.5","Single Cell Type RNA - Kupffer cells [nTPM]":"108.1","Single Cell Type RNA - Langerhans cells [nTPM]":"88.8","Single Cell Type RNA - Late spermatids [nTPM]":"15.6","Single Cell Type RNA - Leydig cells [nTPM]":"104.4","Single Cell Type RNA - Macrophages [nTPM]":"89.4","Single Cell Type RNA - Melanocytes [nTPM]":"96.0","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"186.2","Single Cell Type RNA - Muller glia cells [nTPM]":"89.5","Single Cell Type RNA - NK-cells [nTPM]":"64.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"131.7","Single Cell Type RNA - Paneth cells [nTPM]":"75.0","Single Cell Type RNA - Peritubular cells [nTPM]":"105.3","Single Cell Type RNA - Plasma cells [nTPM]":"89.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"75.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"117.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"148.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"141.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"62.8","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"86.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"127.5","Single Cell Type RNA - Spermatocytes [nTPM]":"54.5","Single Cell Type RNA - Spermatogonia [nTPM]":"49.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"80.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"75.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"267.3","Single Cell Type RNA - T-cells [nTPM]":"80.2","Single Cell Type RNA - Theca cells [nTPM]":"124.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"96.0","Single Cell Type RNA - Urothelial cells [nTPM]":"89.1"},{"Gene":"PSPH","Gene synonym":["PSP"],"Ensembl":"ENSG00000146733","Gene description":"Phosphoserine phosphatase","Uniprot":["P78330"],"Chromosome":"7","Position":"56011051-56051604","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Amino-acid biosynthesis","Serine biosynthesis"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"107.6","Early spermatids":"149.8","Late spermatids":"211.5","Proximal tubular cells":"91.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"41.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020376","HPA029515"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA020376":"AB_1855867","HPA029515":"AB_10601492"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.30e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.75e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.77e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-3"},"Tissue RNA - adipose tissue [nTPM]":"4.7","Tissue RNA - adrenal gland [nTPM]":"9.4","Tissue RNA - amygdala [nTPM]":"11.0","Tissue RNA - appendix [nTPM]":"3.7","Tissue RNA - basal ganglia [nTPM]":"12.4","Tissue RNA - bone marrow [nTPM]":"3.7","Tissue RNA - breast [nTPM]":"3.9","Tissue RNA - cerebellum [nTPM]":"11.8","Tissue RNA - cerebral cortex [nTPM]":"10.8","Tissue RNA - cervix [nTPM]":"4.7","Tissue RNA - choroid plexus [nTPM]":"13.3","Tissue RNA - colon [nTPM]":"4.8","Tissue RNA - duodenum [nTPM]":"4.2","Tissue RNA - endometrium 1 [nTPM]":"4.9","Tissue RNA - epididymis [nTPM]":"5.2","Tissue RNA - esophagus [nTPM]":"8.7","Tissue RNA - fallopian tube [nTPM]":"16.1","Tissue RNA - gallbladder [nTPM]":"5.9","Tissue RNA - heart muscle [nTPM]":"8.1","Tissue RNA - hippocampal formation [nTPM]":"11.0","Tissue RNA - hypothalamus [nTPM]":"11.0","Tissue RNA - kidney [nTPM]":"10.0","Tissue RNA - liver [nTPM]":"6.8","Tissue RNA - lung [nTPM]":"3.5","Tissue RNA - lymph node [nTPM]":"5.1","Tissue RNA - medulla oblongata [nTPM]":"12.3","Tissue RNA - midbrain [nTPM]":"12.9","Tissue RNA - ovary [nTPM]":"8.2","Tissue RNA - pancreas [nTPM]":"6.7","Tissue RNA - parathyroid gland [nTPM]":"6.6","Tissue RNA - pituitary gland [nTPM]":"9.4","Tissue RNA - placenta [nTPM]":"3.7","Tissue RNA - pons [nTPM]":"11.7","Tissue RNA - prostate [nTPM]":"6.4","Tissue RNA - rectum [nTPM]":"4.4","Tissue RNA - retina [nTPM]":"4.4","Tissue RNA - salivary gland [nTPM]":"4.5","Tissue RNA - seminal vesicle [nTPM]":"6.4","Tissue RNA - skeletal muscle [nTPM]":"4.6","Tissue RNA - skin 1 [nTPM]":"4.2","Tissue RNA - small intestine [nTPM]":"4.1","Tissue RNA - smooth muscle [nTPM]":"5.1","Tissue RNA - spinal cord [nTPM]":"12.2","Tissue RNA - spleen [nTPM]":"3.9","Tissue RNA - stomach 1 [nTPM]":"6.2","Tissue RNA - testis [nTPM]":"7.1","Tissue RNA - thalamus [nTPM]":"12.1","Tissue RNA - thymus [nTPM]":"5.8","Tissue RNA - thyroid gland [nTPM]":"7.0","Tissue RNA - tongue [nTPM]":"6.0","Tissue RNA - tonsil [nTPM]":"5.9","Tissue RNA - urinary bladder [nTPM]":"5.2","Tissue RNA - vagina [nTPM]":"5.7","Tissue RNA - white matter [nTPM]":"16.1","Cell RNA - A-431 [nTPM]":"130.1","Cell RNA - A549 [nTPM]":"37.6","Cell RNA - AF22 [nTPM]":"23.1","Cell RNA - AN3-CA [nTPM]":"93.0","Cell RNA - ASC diff [nTPM]":"18.9","Cell RNA - ASC TERT1 [nTPM]":"25.3","Cell RNA - BEWO [nTPM]":"16.7","Cell RNA - BJ [nTPM]":"32.5","Cell RNA - BJ hTERT+ [nTPM]":"18.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"32.7","Cell RNA - CACO-2 [nTPM]":"34.7","Cell RNA - CAPAN-2 [nTPM]":"23.5","Cell RNA - Daudi [nTPM]":"62.9","Cell RNA - EFO-21 [nTPM]":"21.0","Cell RNA - fHDF\/TERT166 [nTPM]":"29.4","Cell RNA - GAMG [nTPM]":"44.5","Cell RNA - HaCaT [nTPM]":"26.9","Cell RNA - HAP1 [nTPM]":"52.6","Cell RNA - HBEC3-KT [nTPM]":"26.9","Cell RNA - HBF TERT88 [nTPM]":"19.0","Cell RNA - HDLM-2 [nTPM]":"48.1","Cell RNA - HEK 293 [nTPM]":"27.9","Cell RNA - HEL [nTPM]":"17.9","Cell RNA - HeLa [nTPM]":"11.1","Cell RNA - Hep G2 [nTPM]":"62.2","Cell RNA - HHSteC [nTPM]":"44.4","Cell RNA - HL-60 [nTPM]":"18.6","Cell RNA - HMC-1 [nTPM]":"26.8","Cell RNA - HSkMC [nTPM]":"31.8","Cell RNA - hTCEpi [nTPM]":"50.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"27.7","Cell RNA - hTERT-HME1 [nTPM]":"32.6","Cell RNA - hTERT-RPE1 [nTPM]":"25.1","Cell RNA - HUVEC TERT2 [nTPM]":"17.7","Cell RNA - JURKAT [nTPM]":"61.2","Cell RNA - K-562 [nTPM]":"44.4","Cell RNA - Karpas-707 [nTPM]":"42.4","Cell RNA - LHCN-M2 [nTPM]":"26.4","Cell RNA - MCF7 [nTPM]":"17.3","Cell RNA - MOLT-4 [nTPM]":"27.7","Cell RNA - NB-4 [nTPM]":"48.3","Cell RNA - NTERA-2 [nTPM]":"38.0","Cell RNA - OE19 [nTPM]":"47.5","Cell RNA - PC-3 [nTPM]":"52.1","Cell RNA - REH [nTPM]":"35.9","Cell RNA - RH-30 [nTPM]":"14.4","Cell RNA - RPMI-8226 [nTPM]":"39.8","Cell RNA - RPTEC TERT1 [nTPM]":"17.2","Cell RNA - RT4 [nTPM]":"6.8","Cell RNA - SCLC-21H [nTPM]":"43.6","Cell RNA - SH-SY5Y [nTPM]":"49.8","Cell RNA - SiHa [nTPM]":"23.5","Cell RNA - SK-BR-3 [nTPM]":"14.9","Cell RNA - SK-MEL-30 [nTPM]":"68.9","Cell RNA - SuSa [nTPM]":"20.9","Cell RNA - T-47d [nTPM]":"44.8","Cell RNA - THP-1 [nTPM]":"41.4","Cell RNA - TIME [nTPM]":"14.5","Cell RNA - U-138 MG [nTPM]":"15.1","Cell RNA - U-2 OS [nTPM]":"24.8","Cell RNA - U-2197 [nTPM]":"45.5","Cell RNA - U-251 MG [nTPM]":"30.3","Cell RNA - U-266\/70 [nTPM]":"26.9","Cell RNA - U-266\/84 [nTPM]":"53.0","Cell RNA - U-698 [nTPM]":"72.8","Cell RNA - U-87 MG [nTPM]":"21.9","Cell RNA - U-937 [nTPM]":"39.9","Cell RNA - WM-115 [nTPM]":"49.7","Blood RNA - basophil [nTPM]":"2.5","Blood RNA - classical monocyte [nTPM]":"6.2","Blood RNA - eosinophil [nTPM]":"5.9","Blood RNA - gdT-cell [nTPM]":"3.1","Blood RNA - intermediate monocyte [nTPM]":"4.4","Blood RNA - MAIT T-cell [nTPM]":"2.3","Blood RNA - memory B-cell [nTPM]":"5.4","Blood RNA - memory CD4 T-cell [nTPM]":"3.0","Blood RNA - memory CD8 T-cell [nTPM]":"3.8","Blood RNA - myeloid DC [nTPM]":"9.6","Blood RNA - naive B-cell [nTPM]":"6.1","Blood RNA - naive CD4 T-cell [nTPM]":"4.5","Blood RNA - naive CD8 T-cell [nTPM]":"4.1","Blood RNA - neutrophil [nTPM]":"2.9","Blood RNA - NK-cell [nTPM]":"4.7","Blood RNA - non-classical monocyte [nTPM]":"7.1","Blood RNA - plasmacytoid DC [nTPM]":"9.3","Blood RNA - T-reg [nTPM]":"4.0","Blood RNA - total PBMC [nTPM]":"4.8","Brain RNA - amygdala [nTPM]":"11.0","Brain RNA - basal ganglia [nTPM]":"12.4","Brain RNA - cerebellum [nTPM]":"11.8","Brain RNA - cerebral cortex [nTPM]":"10.8","Brain RNA - hippocampal formation [nTPM]":"11.0","Brain RNA - hypothalamus [nTPM]":"11.0","Brain RNA - medulla oblongata [nTPM]":"12.3","Brain RNA - midbrain [nTPM]":"12.9","Brain RNA - pons [nTPM]":"11.7","Brain RNA - spinal cord [nTPM]":"12.2","Brain RNA - thalamus [nTPM]":"12.1","Brain RNA - white matter [nTPM]":"16.1","Single Cell Type RNA - Adipocytes [nTPM]":"2.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.5","Single Cell Type RNA - Astrocytes [nTPM]":"11.4","Single Cell Type RNA - B-cells [nTPM]":"5.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"20.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"5.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"11.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.8","Single Cell Type RNA - dendritic cells [nTPM]":"4.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"107.6","Single Cell Type RNA - Ductal cells [nTPM]":"8.6","Single Cell Type RNA - Early spermatids [nTPM]":"149.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"62.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.4","Single Cell Type RNA - Endothelial cells [nTPM]":"4.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"7.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.5","Single Cell Type RNA - Fibroblasts [nTPM]":"9.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.4","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"16.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"9.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.5","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"4.4","Single Cell Type RNA - Langerhans cells [nTPM]":"5.8","Single Cell Type RNA - Late spermatids [nTPM]":"211.5","Single Cell Type RNA - Leydig cells [nTPM]":"8.4","Single Cell Type RNA - Macrophages [nTPM]":"4.3","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"5.7","Single Cell Type RNA - Muller glia cells [nTPM]":"46.8","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"13.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.1","Single Cell Type RNA - Paneth cells [nTPM]":"3.5","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"10.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"91.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.0","Single Cell Type RNA - Spermatocytes [nTPM]":"30.1","Single Cell Type RNA - Spermatogonia [nTPM]":"22.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.7","Single Cell Type RNA - T-cells [nTPM]":"3.9","Single Cell Type RNA - Theca cells [nTPM]":"16.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.3","Single Cell Type RNA - Urothelial cells [nTPM]":"7.7"},{"Gene":"PTCH1","Gene synonym":["BCNS","NBCCS","PTCH"],"Ensembl":"ENSG00000185920","Gene description":"Patched 1","Uniprot":["Q13635"],"Chromosome":"9","Position":"95442980-95517057","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","Holoprosencephaly","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"26.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"237.5","Leydig cells":"191.0","Peritubular cells":"444.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"6.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"T-cells":"6.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"NTERA-2":"29.6","WM-115":"71.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013717","HPA075072"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB013717":null,"HPA075072":"AB_2686733"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.0","Tissue RNA - adrenal gland [nTPM]":"3.5","Tissue RNA - amygdala [nTPM]":"9.5","Tissue RNA - appendix [nTPM]":"4.0","Tissue RNA - basal ganglia [nTPM]":"11.6","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"2.8","Tissue RNA - cerebellum [nTPM]":"24.6","Tissue RNA - cerebral cortex [nTPM]":"5.6","Tissue RNA - cervix [nTPM]":"26.7","Tissue RNA - choroid plexus [nTPM]":"2.7","Tissue RNA - colon [nTPM]":"11.3","Tissue RNA - duodenum [nTPM]":"8.1","Tissue RNA - endometrium 1 [nTPM]":"15.6","Tissue RNA - epididymis [nTPM]":"2.7","Tissue RNA - esophagus [nTPM]":"2.9","Tissue RNA - fallopian tube [nTPM]":"7.1","Tissue RNA - gallbladder [nTPM]":"8.1","Tissue RNA - heart muscle [nTPM]":"2.9","Tissue RNA - hippocampal formation [nTPM]":"4.7","Tissue RNA - hypothalamus [nTPM]":"17.8","Tissue RNA - kidney [nTPM]":"4.6","Tissue RNA - liver [nTPM]":"2.2","Tissue RNA - lung [nTPM]":"5.5","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"16.0","Tissue RNA - midbrain [nTPM]":"12.7","Tissue RNA - ovary [nTPM]":"5.0","Tissue RNA - pancreas [nTPM]":"6.4","Tissue RNA - parathyroid gland [nTPM]":"2.5","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"3.8","Tissue RNA - pons [nTPM]":"8.0","Tissue RNA - prostate [nTPM]":"6.8","Tissue RNA - rectum [nTPM]":"12.3","Tissue RNA - retina [nTPM]":"8.3","Tissue RNA - salivary gland [nTPM]":"7.5","Tissue RNA - seminal vesicle [nTPM]":"4.0","Tissue RNA - skeletal muscle [nTPM]":"3.0","Tissue RNA - skin 1 [nTPM]":"3.2","Tissue RNA - small intestine [nTPM]":"11.6","Tissue RNA - smooth muscle [nTPM]":"2.4","Tissue RNA - spinal cord [nTPM]":"7.0","Tissue RNA - spleen [nTPM]":"3.3","Tissue RNA - stomach 1 [nTPM]":"12.5","Tissue RNA - testis [nTPM]":"14.5","Tissue RNA - thalamus [nTPM]":"24.0","Tissue RNA - thymus [nTPM]":"2.1","Tissue RNA - thyroid gland [nTPM]":"4.7","Tissue RNA - tongue [nTPM]":"4.8","Tissue RNA - tonsil [nTPM]":"3.0","Tissue RNA - urinary bladder [nTPM]":"7.2","Tissue RNA - vagina [nTPM]":"2.9","Tissue RNA - white matter [nTPM]":"4.5","Cell RNA - A-431 [nTPM]":"10.1","Cell RNA - A549 [nTPM]":"4.7","Cell RNA - AF22 [nTPM]":"20.3","Cell RNA - AN3-CA [nTPM]":"12.9","Cell RNA - ASC diff [nTPM]":"3.0","Cell RNA - ASC TERT1 [nTPM]":"5.0","Cell RNA - BEWO [nTPM]":"11.4","Cell RNA - BJ [nTPM]":"1.9","Cell RNA - BJ hTERT+ [nTPM]":"1.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.4","Cell RNA - CACO-2 [nTPM]":"4.9","Cell RNA - CAPAN-2 [nTPM]":"4.8","Cell RNA - Daudi [nTPM]":"8.0","Cell RNA - EFO-21 [nTPM]":"3.3","Cell RNA - fHDF\/TERT166 [nTPM]":"3.8","Cell RNA - GAMG [nTPM]":"4.4","Cell RNA - HaCaT [nTPM]":"22.3","Cell RNA - HAP1 [nTPM]":"11.7","Cell RNA - HBEC3-KT [nTPM]":"1.6","Cell RNA - HBF TERT88 [nTPM]":"1.4","Cell RNA - HDLM-2 [nTPM]":"7.9","Cell RNA - HEK 293 [nTPM]":"7.8","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"4.8","Cell RNA - Hep G2 [nTPM]":"2.3","Cell RNA - HHSteC [nTPM]":"2.7","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"4.2","Cell RNA - HSkMC [nTPM]":"4.7","Cell RNA - hTCEpi [nTPM]":"2.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.2","Cell RNA - hTERT-HME1 [nTPM]":"1.4","Cell RNA - hTERT-RPE1 [nTPM]":"4.3","Cell RNA - HUVEC TERT2 [nTPM]":"4.2","Cell RNA - JURKAT [nTPM]":"3.5","Cell RNA - K-562 [nTPM]":"7.3","Cell RNA - Karpas-707 [nTPM]":"9.1","Cell RNA - LHCN-M2 [nTPM]":"1.0","Cell RNA - MCF7 [nTPM]":"1.9","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"3.2","Cell RNA - NTERA-2 [nTPM]":"29.6","Cell RNA - OE19 [nTPM]":"7.2","Cell RNA - PC-3 [nTPM]":"1.8","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"15.5","Cell RNA - RPMI-8226 [nTPM]":"4.2","Cell RNA - RPTEC TERT1 [nTPM]":"1.6","Cell RNA - RT4 [nTPM]":"1.5","Cell RNA - SCLC-21H [nTPM]":"13.8","Cell RNA - SH-SY5Y [nTPM]":"7.0","Cell RNA - SiHa [nTPM]":"7.1","Cell RNA - SK-BR-3 [nTPM]":"6.8","Cell RNA - SK-MEL-30 [nTPM]":"2.9","Cell RNA - SuSa [nTPM]":"18.8","Cell RNA - T-47d [nTPM]":"1.8","Cell RNA - THP-1 [nTPM]":"2.1","Cell RNA - TIME [nTPM]":"1.1","Cell RNA - U-138 MG [nTPM]":"2.6","Cell RNA - U-2 OS [nTPM]":"12.9","Cell RNA - U-2197 [nTPM]":"13.6","Cell RNA - U-251 MG [nTPM]":"1.5","Cell RNA - U-266\/70 [nTPM]":"18.0","Cell RNA - U-266\/84 [nTPM]":"16.8","Cell RNA - U-698 [nTPM]":"5.3","Cell RNA - U-87 MG [nTPM]":"3.8","Cell RNA - U-937 [nTPM]":"3.9","Cell RNA - WM-115 [nTPM]":"71.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"6.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"3.3","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"2.5","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.9","Blood RNA - naive CD8 T-cell [nTPM]":"2.2","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"1.7","Brain RNA - amygdala [nTPM]":"9.5","Brain RNA - basal ganglia [nTPM]":"11.6","Brain RNA - cerebellum [nTPM]":"24.6","Brain RNA - cerebral cortex [nTPM]":"5.6","Brain RNA - hippocampal formation [nTPM]":"4.7","Brain RNA - hypothalamus [nTPM]":"17.8","Brain RNA - medulla oblongata [nTPM]":"16.0","Brain RNA - midbrain [nTPM]":"12.7","Brain RNA - pons [nTPM]":"8.0","Brain RNA - spinal cord [nTPM]":"7.0","Brain RNA - thalamus [nTPM]":"24.0","Brain RNA - white matter [nTPM]":"4.5","Single Cell Type RNA - Adipocytes [nTPM]":"6.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.4","Single Cell Type RNA - Astrocytes [nTPM]":"49.0","Single Cell Type RNA - B-cells [nTPM]":"3.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"20.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"2.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.0","Single Cell Type RNA - dendritic cells [nTPM]":"11.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.5","Single Cell Type RNA - Early spermatids [nTPM]":"88.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"89.8","Single Cell Type RNA - Endothelial cells [nTPM]":"5.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.7","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.9","Single Cell Type RNA - Fibroblasts [nTPM]":"27.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"2.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"2.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.8","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.9","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"237.5","Single Cell Type RNA - Leydig cells [nTPM]":"191.0","Single Cell Type RNA - Macrophages [nTPM]":"1.4","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"0.8","Single Cell Type RNA - Muller glia cells [nTPM]":"55.6","Single Cell Type RNA - NK-cells [nTPM]":"54.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"39.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.4","Single Cell Type RNA - Paneth cells [nTPM]":"3.1","Single Cell Type RNA - Peritubular cells [nTPM]":"444.5","Single Cell Type RNA - Plasma cells [nTPM]":"3.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.4","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.4","Single Cell Type RNA - Spermatocytes [nTPM]":"4.4","Single Cell Type RNA - Spermatogonia [nTPM]":"35.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - T-cells [nTPM]":"6.5","Single Cell Type RNA - Theca cells [nTPM]":"71.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.7","Single Cell Type RNA - Urothelial cells [nTPM]":"1.4"},{"Gene":"PTCH2","Gene synonym":[],"Ensembl":"ENSG00000117425","Gene description":"Patched 2","Uniprot":["Q9Y6C5"],"Chromosome":"1","Position":"44819844-44843253","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"ovary":"24.6","parathyroid gland":"59.1","salivary gland":"75.2","testis":"25.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Leydig cells":"107.8","Peritubular cells":"68.1","Plasma cells":"67.1","Theca cells":"138.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"9.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-266\/84":"11.6"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046839"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA046839":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.74e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.2","Tissue RNA - adrenal gland [nTPM]":"3.1","Tissue RNA - amygdala [nTPM]":"6.1","Tissue RNA - appendix [nTPM]":"0.8","Tissue RNA - basal ganglia [nTPM]":"3.5","Tissue RNA - bone marrow [nTPM]":"9.4","Tissue RNA - breast [nTPM]":"3.4","Tissue RNA - cerebellum [nTPM]":"6.8","Tissue RNA - cerebral cortex [nTPM]":"6.8","Tissue RNA - cervix [nTPM]":"5.1","Tissue RNA - choroid plexus [nTPM]":"3.6","Tissue RNA - colon [nTPM]":"3.6","Tissue RNA - duodenum [nTPM]":"1.0","Tissue RNA - endometrium 1 [nTPM]":"6.4","Tissue RNA - epididymis [nTPM]":"1.6","Tissue RNA - esophagus [nTPM]":"0.9","Tissue RNA - fallopian tube [nTPM]":"4.3","Tissue RNA - gallbladder [nTPM]":"2.5","Tissue RNA - heart muscle [nTPM]":"1.3","Tissue RNA - hippocampal formation [nTPM]":"3.1","Tissue RNA - hypothalamus [nTPM]":"4.4","Tissue RNA - kidney [nTPM]":"1.3","Tissue RNA - liver [nTPM]":"1.3","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"2.3","Tissue RNA - medulla oblongata [nTPM]":"2.9","Tissue RNA - midbrain [nTPM]":"4.8","Tissue RNA - ovary [nTPM]":"24.6","Tissue RNA - pancreas [nTPM]":"1.0","Tissue RNA - parathyroid gland [nTPM]":"59.1","Tissue RNA - pituitary gland [nTPM]":"9.9","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"2.0","Tissue RNA - prostate [nTPM]":"3.0","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"3.6","Tissue RNA - salivary gland [nTPM]":"75.2","Tissue RNA - seminal vesicle [nTPM]":"1.3","Tissue RNA - skeletal muscle [nTPM]":"2.0","Tissue RNA - skin 1 [nTPM]":"3.6","Tissue RNA - small intestine [nTPM]":"1.8","Tissue RNA - smooth muscle [nTPM]":"1.2","Tissue RNA - spinal cord [nTPM]":"1.6","Tissue RNA - spleen [nTPM]":"2.4","Tissue RNA - stomach 1 [nTPM]":"2.0","Tissue RNA - testis [nTPM]":"25.6","Tissue RNA - thalamus [nTPM]":"6.5","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"4.6","Tissue RNA - tongue [nTPM]":"0.8","Tissue RNA - tonsil [nTPM]":"0.7","Tissue RNA - urinary bladder [nTPM]":"3.1","Tissue RNA - vagina [nTPM]":"3.4","Tissue RNA - white matter [nTPM]":"4.8","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"1.0","Cell RNA - AN3-CA [nTPM]":"2.5","Cell RNA - ASC diff [nTPM]":"0.8","Cell RNA - ASC TERT1 [nTPM]":"0.9","Cell RNA - BEWO [nTPM]":"1.0","Cell RNA - BJ [nTPM]":"0.8","Cell RNA - BJ hTERT+ [nTPM]":"1.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"1.1","Cell RNA - EFO-21 [nTPM]":"0.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"1.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"2.1","Cell RNA - HEK 293 [nTPM]":"1.9","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"1.0","Cell RNA - Hep G2 [nTPM]":"0.8","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"0.7","Cell RNA - HMC-1 [nTPM]":"1.1","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"1.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"1.0","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"1.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.5","Cell RNA - MOLT-4 [nTPM]":"1.4","Cell RNA - NB-4 [nTPM]":"2.1","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"1.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.5","Cell RNA - SH-SY5Y [nTPM]":"0.6","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"0.8","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"1.2","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"1.3","Cell RNA - U-251 MG [nTPM]":"0.5","Cell RNA - U-266\/70 [nTPM]":"1.9","Cell RNA - U-266\/84 [nTPM]":"11.6","Cell RNA - U-698 [nTPM]":"3.2","Cell RNA - U-87 MG [nTPM]":"0.6","Cell RNA - U-937 [nTPM]":"3.0","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"2.5","Blood RNA - classical monocyte [nTPM]":"1.9","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"1.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"1.2","Blood RNA - naive B-cell [nTPM]":"1.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"0.9","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"3.6","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"6.1","Brain RNA - basal ganglia [nTPM]":"3.5","Brain RNA - cerebellum [nTPM]":"6.8","Brain RNA - cerebral cortex [nTPM]":"6.8","Brain RNA - hippocampal formation [nTPM]":"3.1","Brain RNA - hypothalamus [nTPM]":"4.4","Brain RNA - medulla oblongata [nTPM]":"2.9","Brain RNA - midbrain [nTPM]":"4.8","Brain RNA - pons [nTPM]":"2.0","Brain RNA - spinal cord [nTPM]":"1.6","Brain RNA - thalamus [nTPM]":"6.5","Brain RNA - white matter [nTPM]":"4.8","Single Cell Type RNA - Adipocytes [nTPM]":"2.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"14.0","Single Cell Type RNA - B-cells [nTPM]":"13.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"1.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.4","Single Cell Type RNA - dendritic cells [nTPM]":"6.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.5","Single Cell Type RNA - Early spermatids [nTPM]":"2.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.5","Single Cell Type RNA - Endothelial cells [nTPM]":"2.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.5","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.6","Single Cell Type RNA - Fibroblasts [nTPM]":"14.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"28.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"4.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"7.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.7","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"27.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.9","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"24.5","Single Cell Type RNA - Langerhans cells [nTPM]":"2.2","Single Cell Type RNA - Late spermatids [nTPM]":"8.0","Single Cell Type RNA - Leydig cells [nTPM]":"107.8","Single Cell Type RNA - Macrophages [nTPM]":"17.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"3.9","Single Cell Type RNA - Muller glia cells [nTPM]":"2.4","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.1","Single Cell Type RNA - Paneth cells [nTPM]":"2.5","Single Cell Type RNA - Peritubular cells [nTPM]":"68.1","Single Cell Type RNA - Plasma cells [nTPM]":"67.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.6","Single Cell Type RNA - Spermatocytes [nTPM]":"5.0","Single Cell Type RNA - Spermatogonia [nTPM]":"3.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.3","Single Cell Type RNA - T-cells [nTPM]":"7.5","Single Cell Type RNA - Theca cells [nTPM]":"138.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"PTDSS1","Gene synonym":["KIAA0024","PSS1","PSSA"],"Ensembl":"ENSG00000156471","Gene description":"Phosphatidylserine synthase 1","Uniprot":["P48651"],"Chromosome":"8","Position":"96261902-96336995","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Dwarfism","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"10.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016852"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA016852":"AB_1855878"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.08e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.83e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.6","Tissue RNA - adrenal gland [nTPM]":"2.2","Tissue RNA - amygdala [nTPM]":"1.6","Tissue RNA - appendix [nTPM]":"3.4","Tissue RNA - basal ganglia [nTPM]":"2.0","Tissue RNA - bone marrow [nTPM]":"4.9","Tissue RNA - breast [nTPM]":"3.1","Tissue RNA - cerebellum [nTPM]":"1.2","Tissue RNA - cerebral cortex [nTPM]":"2.6","Tissue RNA - cervix [nTPM]":"3.5","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"3.4","Tissue RNA - duodenum [nTPM]":"4.1","Tissue RNA - endometrium 1 [nTPM]":"2.1","Tissue RNA - epididymis [nTPM]":"2.8","Tissue RNA - esophagus [nTPM]":"3.7","Tissue RNA - fallopian tube [nTPM]":"2.5","Tissue RNA - gallbladder [nTPM]":"3.1","Tissue RNA - heart muscle [nTPM]":"7.2","Tissue RNA - hippocampal formation [nTPM]":"1.8","Tissue RNA - hypothalamus [nTPM]":"1.0","Tissue RNA - kidney [nTPM]":"3.7","Tissue RNA - liver [nTPM]":"4.6","Tissue RNA - lung [nTPM]":"2.6","Tissue RNA - lymph node [nTPM]":"5.6","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.6","Tissue RNA - ovary [nTPM]":"3.6","Tissue RNA - pancreas [nTPM]":"2.7","Tissue RNA - parathyroid gland [nTPM]":"8.0","Tissue RNA - pituitary gland [nTPM]":"0.6","Tissue RNA - placenta [nTPM]":"4.6","Tissue RNA - pons [nTPM]":"1.3","Tissue RNA - prostate [nTPM]":"1.9","Tissue RNA - rectum [nTPM]":"2.9","Tissue RNA - retina [nTPM]":"0.9","Tissue RNA - salivary gland [nTPM]":"2.0","Tissue RNA - seminal vesicle [nTPM]":"3.5","Tissue RNA - skeletal muscle [nTPM]":"2.9","Tissue RNA - skin 1 [nTPM]":"3.2","Tissue RNA - small intestine [nTPM]":"3.2","Tissue RNA - smooth muscle [nTPM]":"3.6","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"2.6","Tissue RNA - stomach 1 [nTPM]":"1.4","Tissue RNA - testis [nTPM]":"1.9","Tissue RNA - thalamus [nTPM]":"2.0","Tissue RNA - thymus [nTPM]":"3.6","Tissue RNA - thyroid gland [nTPM]":"4.5","Tissue RNA - tongue [nTPM]":"3.0","Tissue RNA - tonsil [nTPM]":"5.2","Tissue RNA - urinary bladder [nTPM]":"2.6","Tissue RNA - vagina [nTPM]":"1.1","Tissue RNA - white matter [nTPM]":"1.4","Cell RNA - A-431 [nTPM]":"14.9","Cell RNA - A549 [nTPM]":"11.6","Cell RNA - AF22 [nTPM]":"2.0","Cell RNA - AN3-CA [nTPM]":"5.5","Cell RNA - ASC diff [nTPM]":"4.2","Cell RNA - ASC TERT1 [nTPM]":"8.5","Cell RNA - BEWO [nTPM]":"3.4","Cell RNA - BJ [nTPM]":"10.6","Cell RNA - BJ hTERT+ [nTPM]":"15.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.5","Cell RNA - CACO-2 [nTPM]":"4.6","Cell RNA - CAPAN-2 [nTPM]":"4.2","Cell RNA - Daudi [nTPM]":"24.9","Cell RNA - EFO-21 [nTPM]":"9.5","Cell RNA - fHDF\/TERT166 [nTPM]":"10.5","Cell RNA - GAMG [nTPM]":"2.1","Cell RNA - HaCaT [nTPM]":"6.0","Cell RNA - HAP1 [nTPM]":"14.1","Cell RNA - HBEC3-KT [nTPM]":"11.1","Cell RNA - HBF TERT88 [nTPM]":"16.1","Cell RNA - HDLM-2 [nTPM]":"12.5","Cell RNA - HEK 293 [nTPM]":"10.3","Cell RNA - HEL [nTPM]":"24.5","Cell RNA - HeLa [nTPM]":"19.8","Cell RNA - Hep G2 [nTPM]":"2.5","Cell RNA - HHSteC [nTPM]":"4.3","Cell RNA - HL-60 [nTPM]":"17.8","Cell RNA - HMC-1 [nTPM]":"8.1","Cell RNA - HSkMC [nTPM]":"7.2","Cell RNA - hTCEpi [nTPM]":"10.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.4","Cell RNA - hTERT-HME1 [nTPM]":"10.2","Cell RNA - hTERT-RPE1 [nTPM]":"2.7","Cell RNA - HUVEC TERT2 [nTPM]":"7.0","Cell RNA - JURKAT [nTPM]":"7.6","Cell RNA - K-562 [nTPM]":"12.5","Cell RNA - Karpas-707 [nTPM]":"12.3","Cell RNA - LHCN-M2 [nTPM]":"9.7","Cell RNA - MCF7 [nTPM]":"4.4","Cell RNA - MOLT-4 [nTPM]":"14.0","Cell RNA - NB-4 [nTPM]":"3.0","Cell RNA - NTERA-2 [nTPM]":"3.1","Cell RNA - OE19 [nTPM]":"5.1","Cell RNA - PC-3 [nTPM]":"11.1","Cell RNA - REH [nTPM]":"10.9","Cell RNA - RH-30 [nTPM]":"10.1","Cell RNA - RPMI-8226 [nTPM]":"18.8","Cell RNA - RPTEC TERT1 [nTPM]":"5.7","Cell RNA - RT4 [nTPM]":"12.5","Cell RNA - SCLC-21H [nTPM]":"8.6","Cell RNA - SH-SY5Y [nTPM]":"3.5","Cell RNA - SiHa [nTPM]":"3.9","Cell RNA - SK-BR-3 [nTPM]":"3.4","Cell RNA - SK-MEL-30 [nTPM]":"1.4","Cell RNA - SuSa [nTPM]":"2.3","Cell RNA - T-47d [nTPM]":"8.2","Cell RNA - THP-1 [nTPM]":"6.3","Cell RNA - TIME [nTPM]":"11.8","Cell RNA - U-138 MG [nTPM]":"9.1","Cell RNA - U-2 OS [nTPM]":"5.5","Cell RNA - U-2197 [nTPM]":"6.3","Cell RNA - U-251 MG [nTPM]":"12.3","Cell RNA - U-266\/70 [nTPM]":"2.5","Cell RNA - U-266\/84 [nTPM]":"13.3","Cell RNA - U-698 [nTPM]":"11.8","Cell RNA - U-87 MG [nTPM]":"5.7","Cell RNA - U-937 [nTPM]":"19.3","Cell RNA - WM-115 [nTPM]":"7.5","Blood RNA - basophil [nTPM]":"10.5","Blood RNA - classical monocyte [nTPM]":"2.6","Blood RNA - eosinophil [nTPM]":"1.5","Blood RNA - gdT-cell [nTPM]":"1.7","Blood RNA - intermediate monocyte [nTPM]":"1.6","Blood RNA - MAIT T-cell [nTPM]":"2.5","Blood RNA - memory B-cell [nTPM]":"1.7","Blood RNA - memory CD4 T-cell [nTPM]":"2.8","Blood RNA - memory CD8 T-cell [nTPM]":"2.2","Blood RNA - myeloid DC [nTPM]":"4.0","Blood RNA - naive B-cell [nTPM]":"2.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.5","Blood RNA - naive CD8 T-cell [nTPM]":"1.8","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"3.2","Blood RNA - non-classical monocyte [nTPM]":"1.7","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"1.7","Blood RNA - total PBMC [nTPM]":"6.7","Brain RNA - amygdala [nTPM]":"1.6","Brain RNA - basal ganglia [nTPM]":"2.0","Brain RNA - cerebellum [nTPM]":"1.2","Brain RNA - cerebral cortex [nTPM]":"2.6","Brain RNA - hippocampal formation [nTPM]":"1.8","Brain RNA - hypothalamus [nTPM]":"1.0","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.6","Brain RNA - pons [nTPM]":"1.3","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"2.0","Brain RNA - white matter [nTPM]":"1.4","Single Cell Type RNA - Adipocytes [nTPM]":"12.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.1","Single Cell Type RNA - Astrocytes [nTPM]":"8.8","Single Cell Type RNA - B-cells [nTPM]":"50.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"31.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"42.7","Single Cell Type RNA - Bipolar cells [nTPM]":"10.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"94.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"15.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"78.4","Single Cell Type RNA - dendritic cells [nTPM]":"23.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"20.5","Single Cell Type RNA - Early spermatids [nTPM]":"60.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.1","Single Cell Type RNA - Endothelial cells [nTPM]":"22.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"38.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"29.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"44.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"54.1","Single Cell Type RNA - Fibroblasts [nTPM]":"18.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.3","Single Cell Type RNA - granulocytes [nTPM]":"32.4","Single Cell Type RNA - Granulosa cells [nTPM]":"17.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"34.2","Single Cell Type RNA - Hepatocytes [nTPM]":"32.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"45.9","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"29.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.1","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"45.3","Single Cell Type RNA - Langerhans cells [nTPM]":"31.5","Single Cell Type RNA - Late spermatids [nTPM]":"52.2","Single Cell Type RNA - Leydig cells [nTPM]":"23.3","Single Cell Type RNA - Macrophages [nTPM]":"36.0","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"39.3","Single Cell Type RNA - Muller glia cells [nTPM]":"4.7","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"21.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"23.9","Single Cell Type RNA - Paneth cells [nTPM]":"11.9","Single Cell Type RNA - Peritubular cells [nTPM]":"25.9","Single Cell Type RNA - Plasma cells [nTPM]":"45.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"21.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"16.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.8","Single Cell Type RNA - Spermatocytes [nTPM]":"12.1","Single Cell Type RNA - Spermatogonia [nTPM]":"18.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"33.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"33.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"80.9","Single Cell Type RNA - T-cells [nTPM]":"34.3","Single Cell Type RNA - Theca cells [nTPM]":"14.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"34.8","Single Cell Type RNA - Urothelial cells [nTPM]":"16.3"},{"Gene":"PTEN","Gene synonym":["BZS","MHAM","MMAC1","PTEN1","TEP1"],"Ensembl":"ENSG00000171862","Gene description":"Phosphatase and tensin homolog","Uniprot":["P60484"],"Chromosome":"10","Position":"87863625-87971930","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Lipid metabolism","Neurogenesis"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":["Autism spectrum disorder","Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"60.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004076","HPA031335"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB004076":"AB_390810","HPA031335":"AB_2797221"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.35e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Tissue RNA - adipose tissue [nTPM]":"64.0","Tissue RNA - adrenal gland [nTPM]":"25.4","Tissue RNA - amygdala [nTPM]":"17.8","Tissue RNA - appendix [nTPM]":"18.6","Tissue RNA - basal ganglia [nTPM]":"19.3","Tissue RNA - bone marrow [nTPM]":"12.9","Tissue RNA - breast [nTPM]":"47.6","Tissue RNA - cerebellum [nTPM]":"34.5","Tissue RNA - cerebral cortex [nTPM]":"23.4","Tissue RNA - cervix [nTPM]":"54.8","Tissue RNA - choroid plexus [nTPM]":"15.6","Tissue RNA - colon [nTPM]":"28.1","Tissue RNA - duodenum [nTPM]":"12.9","Tissue RNA - endometrium 1 [nTPM]":"27.4","Tissue RNA - epididymis [nTPM]":"18.6","Tissue RNA - esophagus [nTPM]":"28.3","Tissue RNA - fallopian tube [nTPM]":"35.2","Tissue RNA - gallbladder [nTPM]":"15.6","Tissue RNA - heart muscle [nTPM]":"29.7","Tissue RNA - hippocampal formation [nTPM]":"20.4","Tissue RNA - hypothalamus [nTPM]":"18.4","Tissue RNA - kidney [nTPM]":"22.6","Tissue RNA - liver [nTPM]":"39.2","Tissue RNA - lung [nTPM]":"39.5","Tissue RNA - lymph node [nTPM]":"21.4","Tissue RNA - medulla oblongata [nTPM]":"16.6","Tissue RNA - midbrain [nTPM]":"17.8","Tissue RNA - ovary [nTPM]":"28.0","Tissue RNA - pancreas [nTPM]":"33.2","Tissue RNA - parathyroid gland [nTPM]":"11.9","Tissue RNA - pituitary gland [nTPM]":"17.3","Tissue RNA - placenta [nTPM]":"30.5","Tissue RNA - pons [nTPM]":"16.4","Tissue RNA - prostate [nTPM]":"26.3","Tissue RNA - rectum [nTPM]":"14.6","Tissue RNA - retina [nTPM]":"30.0","Tissue RNA - salivary gland [nTPM]":"19.6","Tissue RNA - seminal vesicle [nTPM]":"16.5","Tissue RNA - skeletal muscle [nTPM]":"23.7","Tissue RNA - skin 1 [nTPM]":"25.9","Tissue RNA - small intestine [nTPM]":"24.5","Tissue RNA - smooth muscle [nTPM]":"22.2","Tissue RNA - spinal cord [nTPM]":"14.5","Tissue RNA - spleen [nTPM]":"40.0","Tissue RNA - stomach 1 [nTPM]":"25.6","Tissue RNA - testis [nTPM]":"28.2","Tissue RNA - thalamus [nTPM]":"19.7","Tissue RNA - thymus [nTPM]":"31.8","Tissue RNA - thyroid gland [nTPM]":"26.1","Tissue RNA - tongue [nTPM]":"14.0","Tissue RNA - tonsil [nTPM]":"16.5","Tissue RNA - urinary bladder [nTPM]":"28.1","Tissue RNA - vagina [nTPM]":"38.4","Tissue RNA - white matter [nTPM]":"17.6","Cell RNA - A-431 [nTPM]":"23.5","Cell RNA - A549 [nTPM]":"10.8","Cell RNA - AF22 [nTPM]":"12.3","Cell RNA - AN3-CA [nTPM]":"11.2","Cell RNA - ASC diff [nTPM]":"28.5","Cell RNA - ASC TERT1 [nTPM]":"19.7","Cell RNA - BEWO [nTPM]":"10.9","Cell RNA - BJ [nTPM]":"12.5","Cell RNA - BJ hTERT+ [nTPM]":"28.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.4","Cell RNA - CACO-2 [nTPM]":"10.9","Cell RNA - CAPAN-2 [nTPM]":"28.0","Cell RNA - Daudi [nTPM]":"28.1","Cell RNA - EFO-21 [nTPM]":"8.0","Cell RNA - fHDF\/TERT166 [nTPM]":"20.9","Cell RNA - GAMG [nTPM]":"8.3","Cell RNA - HaCaT [nTPM]":"14.1","Cell RNA - HAP1 [nTPM]":"16.6","Cell RNA - HBEC3-KT [nTPM]":"14.3","Cell RNA - HBF TERT88 [nTPM]":"22.8","Cell RNA - HDLM-2 [nTPM]":"14.1","Cell RNA - HEK 293 [nTPM]":"4.7","Cell RNA - HEL [nTPM]":"9.3","Cell RNA - HeLa [nTPM]":"28.5","Cell RNA - Hep G2 [nTPM]":"13.8","Cell RNA - HHSteC [nTPM]":"30.1","Cell RNA - HL-60 [nTPM]":"31.9","Cell RNA - HMC-1 [nTPM]":"15.3","Cell RNA - HSkMC [nTPM]":"13.5","Cell RNA - hTCEpi [nTPM]":"38.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.0","Cell RNA - hTERT-HME1 [nTPM]":"23.7","Cell RNA - hTERT-RPE1 [nTPM]":"60.3","Cell RNA - HUVEC TERT2 [nTPM]":"20.8","Cell RNA - JURKAT [nTPM]":"17.7","Cell RNA - K-562 [nTPM]":"7.0","Cell RNA - Karpas-707 [nTPM]":"72.6","Cell RNA - LHCN-M2 [nTPM]":"13.5","Cell RNA - MCF7 [nTPM]":"18.1","Cell RNA - MOLT-4 [nTPM]":"17.8","Cell RNA - NB-4 [nTPM]":"56.3","Cell RNA - NTERA-2 [nTPM]":"4.6","Cell RNA - OE19 [nTPM]":"19.9","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"27.6","Cell RNA - RH-30 [nTPM]":"6.4","Cell RNA - RPMI-8226 [nTPM]":"20.8","Cell RNA - RPTEC TERT1 [nTPM]":"22.9","Cell RNA - RT4 [nTPM]":"13.4","Cell RNA - SCLC-21H [nTPM]":"4.5","Cell RNA - SH-SY5Y [nTPM]":"19.9","Cell RNA - SiHa [nTPM]":"16.6","Cell RNA - SK-BR-3 [nTPM]":"7.9","Cell RNA - SK-MEL-30 [nTPM]":"23.0","Cell RNA - SuSa [nTPM]":"9.7","Cell RNA - T-47d [nTPM]":"21.9","Cell RNA - THP-1 [nTPM]":"45.2","Cell RNA - TIME [nTPM]":"17.9","Cell RNA - U-138 MG [nTPM]":"44.6","Cell RNA - U-2 OS [nTPM]":"10.8","Cell RNA - U-2197 [nTPM]":"18.3","Cell RNA - U-251 MG [nTPM]":"10.1","Cell RNA - U-266\/70 [nTPM]":"23.9","Cell RNA - U-266\/84 [nTPM]":"32.9","Cell RNA - U-698 [nTPM]":"30.7","Cell RNA - U-87 MG [nTPM]":"14.6","Cell RNA - U-937 [nTPM]":"29.2","Cell RNA - WM-115 [nTPM]":"2.9","Blood RNA - basophil [nTPM]":"21.3","Blood RNA - classical monocyte [nTPM]":"14.2","Blood RNA - eosinophil [nTPM]":"25.8","Blood RNA - gdT-cell [nTPM]":"6.8","Blood RNA - intermediate monocyte [nTPM]":"21.8","Blood RNA - MAIT T-cell [nTPM]":"7.2","Blood RNA - memory B-cell [nTPM]":"7.9","Blood RNA - memory CD4 T-cell [nTPM]":"7.2","Blood RNA - memory CD8 T-cell [nTPM]":"6.6","Blood RNA - myeloid DC [nTPM]":"10.3","Blood RNA - naive B-cell [nTPM]":"6.8","Blood RNA - naive CD4 T-cell [nTPM]":"8.3","Blood RNA - naive CD8 T-cell [nTPM]":"8.3","Blood RNA - neutrophil [nTPM]":"60.5","Blood RNA - NK-cell [nTPM]":"8.9","Blood RNA - non-classical monocyte [nTPM]":"15.6","Blood RNA - plasmacytoid DC [nTPM]":"8.2","Blood RNA - T-reg [nTPM]":"7.0","Blood RNA - total PBMC [nTPM]":"4.5","Brain RNA - amygdala [nTPM]":"17.8","Brain RNA - basal ganglia [nTPM]":"19.3","Brain RNA - cerebellum [nTPM]":"34.5","Brain RNA - cerebral cortex [nTPM]":"23.4","Brain RNA - hippocampal formation [nTPM]":"20.4","Brain RNA - hypothalamus [nTPM]":"18.4","Brain RNA - medulla oblongata [nTPM]":"16.6","Brain RNA - midbrain [nTPM]":"17.8","Brain RNA - pons [nTPM]":"16.4","Brain RNA - spinal cord [nTPM]":"14.5","Brain RNA - thalamus [nTPM]":"19.7","Brain RNA - white matter [nTPM]":"17.6","Single Cell Type RNA - Adipocytes [nTPM]":"67.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"63.3","Single Cell Type RNA - Astrocytes [nTPM]":"83.6","Single Cell Type RNA - B-cells [nTPM]":"48.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"56.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"57.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"31.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"47.3","Single Cell Type RNA - Bipolar cells [nTPM]":"113.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"49.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"41.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"46.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"57.2","Single Cell Type RNA - Club cells [nTPM]":"31.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.8","Single Cell Type RNA - dendritic cells [nTPM]":"64.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"57.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"24.7","Single Cell Type RNA - Early spermatids [nTPM]":"70.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"40.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"114.5","Single Cell Type RNA - Endothelial cells [nTPM]":"56.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"31.2","Single Cell Type RNA - Erythroid cells [nTPM]":"52.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"141.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"62.2","Single Cell Type RNA - Fibroblasts [nTPM]":"79.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"39.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"33.6","Single Cell Type RNA - granulocytes [nTPM]":"25.4","Single Cell Type RNA - Granulosa cells [nTPM]":"39.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"53.9","Single Cell Type RNA - Hepatocytes [nTPM]":"64.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"35.0","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"132.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"44.7","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"206.1","Single Cell Type RNA - Langerhans cells [nTPM]":"97.2","Single Cell Type RNA - Late spermatids [nTPM]":"92.1","Single Cell Type RNA - Leydig cells [nTPM]":"56.8","Single Cell Type RNA - Macrophages [nTPM]":"105.2","Single Cell Type RNA - Melanocytes [nTPM]":"62.2","Single Cell Type RNA - Microglial cells [nTPM]":"196.8","Single Cell Type RNA - monocytes [nTPM]":"101.5","Single Cell Type RNA - Muller glia cells [nTPM]":"61.6","Single Cell Type RNA - NK-cells [nTPM]":"44.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"139.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"95.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"30.6","Single Cell Type RNA - Paneth cells [nTPM]":"39.7","Single Cell Type RNA - Peritubular cells [nTPM]":"54.5","Single Cell Type RNA - Plasma cells [nTPM]":"39.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"45.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"50.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"38.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"31.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"61.2","Single Cell Type RNA - Sertoli cells [nTPM]":"92.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"66.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"170.7","Single Cell Type RNA - Spermatocytes [nTPM]":"33.5","Single Cell Type RNA - Spermatogonia [nTPM]":"25.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"45.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"60.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"57.3","Single Cell Type RNA - T-cells [nTPM]":"46.3","Single Cell Type RNA - Theca cells [nTPM]":"44.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"46.1","Single Cell Type RNA - Urothelial cells [nTPM]":"64.0"},{"Gene":"PTGDR","Gene synonym":["DP","DP1","PTGDR1"],"Ensembl":"ENSG00000168229","Gene description":"Prostaglandin D2 receptor","Uniprot":["Q13258"],"Chromosome":"14","Position":"52267698-52276724","Protein class":["Disease related genes","G-protein coupled receptors","Potential drug targets","Predicted membrane proteins"],"Biological process":["Mast cell degranulation"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Asthma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"7.9","lymphoid tissue":"6.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"50.6","NK-cells":"187.4","T-cells":"31.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"1.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"68.0","NK-cell":"90.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"33","RNA blood lineage specific nTPM":{"NK-cells":"90.3","T-cells":"68.0"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049668"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049668":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.32e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.38e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.0","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"2.1","Tissue RNA - basal ganglia [nTPM]":"1.7","Tissue RNA - bone marrow [nTPM]":"1.4","Tissue RNA - breast [nTPM]":"1.2","Tissue RNA - cerebellum [nTPM]":"0.8","Tissue RNA - cerebral cortex [nTPM]":"0.7","Tissue RNA - cervix [nTPM]":"2.1","Tissue RNA - choroid plexus [nTPM]":"2.6","Tissue RNA - colon [nTPM]":"5.6","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"1.5","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"1.3","Tissue RNA - gallbladder [nTPM]":"1.6","Tissue RNA - heart muscle [nTPM]":"1.9","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"0.5","Tissue RNA - liver [nTPM]":"1.1","Tissue RNA - lung [nTPM]":"1.7","Tissue RNA - lymph node [nTPM]":"3.2","Tissue RNA - medulla oblongata [nTPM]":"2.4","Tissue RNA - midbrain [nTPM]":"0.6","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"0.8","Tissue RNA - rectum [nTPM]":"7.9","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"1.1","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"0.6","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"1.4","Tissue RNA - smooth muscle [nTPM]":"0.8","Tissue RNA - spinal cord [nTPM]":"1.5","Tissue RNA - spleen [nTPM]":"6.3","Tissue RNA - stomach 1 [nTPM]":"1.3","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"0.9","Tissue RNA - thyroid gland [nTPM]":"1.1","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"1.1","Tissue RNA - urinary bladder [nTPM]":"0.9","Tissue RNA - vagina [nTPM]":"1.3","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"68.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"33.5","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"9.0","Blood RNA - memory CD8 T-cell [nTPM]":"40.9","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.4","Blood RNA - naive CD8 T-cell [nTPM]":"22.5","Blood RNA - neutrophil [nTPM]":"2.3","Blood RNA - NK-cell [nTPM]":"90.3","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"12.9","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"1.7","Brain RNA - cerebellum [nTPM]":"0.8","Brain RNA - cerebral cortex [nTPM]":"0.7","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"2.4","Brain RNA - midbrain [nTPM]":"0.6","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"1.5","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"2.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"50.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"2.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"4.6","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"187.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"2.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"4.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"31.4","Single Cell Type RNA - Theca cells [nTPM]":"2.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PTK2","Gene synonym":["FADK","FAK","FAK1","PPP1R71"],"Ensembl":"ENSG00000169398","Gene description":"Protein tyrosine kinase 2","Uniprot":["Q05397"],"Chromosome":"8","Position":"140657900-141002216","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Angiogenesis"],"Molecular function":["Developmental protein","Kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"295.2","Excitatory neurons":"584.9","Oligodendrocyte precursor cells":"353.9","Oligodendrocytes":"791.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001842","CAB004036","HPA029671"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Focal adhesion sites","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"25000","Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Focal adhesion sites"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"CAB004036":"AB_2269034","HPA001842":"AB_1855891","HPA029671":"AB_10610288"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.21e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.11e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-2"},"Tissue RNA - adipose tissue [nTPM]":"51.0","Tissue RNA - adrenal gland [nTPM]":"40.4","Tissue RNA - amygdala [nTPM]":"83.8","Tissue RNA - appendix [nTPM]":"19.5","Tissue RNA - basal ganglia [nTPM]":"115.1","Tissue RNA - bone marrow [nTPM]":"6.7","Tissue RNA - breast [nTPM]":"42.1","Tissue RNA - cerebellum [nTPM]":"62.4","Tissue RNA - cerebral cortex [nTPM]":"99.9","Tissue RNA - cervix [nTPM]":"40.3","Tissue RNA - choroid plexus [nTPM]":"51.0","Tissue RNA - colon [nTPM]":"37.2","Tissue RNA - duodenum [nTPM]":"25.8","Tissue RNA - endometrium 1 [nTPM]":"37.3","Tissue RNA - epididymis [nTPM]":"49.7","Tissue RNA - esophagus [nTPM]":"25.6","Tissue RNA - fallopian tube [nTPM]":"34.0","Tissue RNA - gallbladder [nTPM]":"32.1","Tissue RNA - heart muscle [nTPM]":"36.9","Tissue RNA - hippocampal formation [nTPM]":"84.5","Tissue RNA - hypothalamus [nTPM]":"77.3","Tissue RNA - kidney [nTPM]":"42.6","Tissue RNA - liver [nTPM]":"30.1","Tissue RNA - lung [nTPM]":"39.4","Tissue RNA - lymph node [nTPM]":"25.3","Tissue RNA - medulla oblongata [nTPM]":"79.1","Tissue RNA - midbrain [nTPM]":"87.6","Tissue RNA - ovary [nTPM]":"33.7","Tissue RNA - pancreas [nTPM]":"32.1","Tissue RNA - parathyroid gland [nTPM]":"53.1","Tissue RNA - pituitary gland [nTPM]":"21.3","Tissue RNA - placenta [nTPM]":"74.2","Tissue RNA - pons [nTPM]":"81.0","Tissue RNA - prostate [nTPM]":"34.0","Tissue RNA - rectum [nTPM]":"35.3","Tissue RNA - retina [nTPM]":"35.5","Tissue RNA - salivary gland [nTPM]":"39.9","Tissue RNA - seminal vesicle [nTPM]":"41.6","Tissue RNA - skeletal muscle [nTPM]":"38.7","Tissue RNA - skin 1 [nTPM]":"29.6","Tissue RNA - small intestine [nTPM]":"29.5","Tissue RNA - smooth muscle [nTPM]":"37.6","Tissue RNA - spinal cord [nTPM]":"67.6","Tissue RNA - spleen [nTPM]":"22.8","Tissue RNA - stomach 1 [nTPM]":"32.8","Tissue RNA - testis [nTPM]":"38.9","Tissue RNA - thalamus [nTPM]":"86.7","Tissue RNA - thymus [nTPM]":"11.9","Tissue RNA - thyroid gland [nTPM]":"38.7","Tissue RNA - tongue [nTPM]":"39.4","Tissue RNA - tonsil [nTPM]":"25.8","Tissue RNA - urinary bladder [nTPM]":"43.9","Tissue RNA - vagina [nTPM]":"34.0","Tissue RNA - white matter [nTPM]":"154.5","Cell RNA - A-431 [nTPM]":"52.6","Cell RNA - A549 [nTPM]":"81.9","Cell RNA - AF22 [nTPM]":"111.0","Cell RNA - AN3-CA [nTPM]":"40.3","Cell RNA - ASC diff [nTPM]":"45.8","Cell RNA - ASC TERT1 [nTPM]":"48.8","Cell RNA - BEWO [nTPM]":"71.6","Cell RNA - BJ [nTPM]":"50.8","Cell RNA - BJ hTERT+ [nTPM]":"70.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"46.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"45.3","Cell RNA - CACO-2 [nTPM]":"35.9","Cell RNA - CAPAN-2 [nTPM]":"42.1","Cell RNA - Daudi [nTPM]":"31.7","Cell RNA - EFO-21 [nTPM]":"111.7","Cell RNA - fHDF\/TERT166 [nTPM]":"65.3","Cell RNA - GAMG [nTPM]":"65.0","Cell RNA - HaCaT [nTPM]":"60.3","Cell RNA - HAP1 [nTPM]":"66.1","Cell RNA - HBEC3-KT [nTPM]":"116.0","Cell RNA - HBF TERT88 [nTPM]":"69.6","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"30.8","Cell RNA - HEL [nTPM]":"70.1","Cell RNA - HeLa [nTPM]":"44.3","Cell RNA - Hep G2 [nTPM]":"50.0","Cell RNA - HHSteC [nTPM]":"62.5","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"31.8","Cell RNA - HSkMC [nTPM]":"33.4","Cell RNA - hTCEpi [nTPM]":"55.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"58.0","Cell RNA - hTERT-HME1 [nTPM]":"81.0","Cell RNA - hTERT-RPE1 [nTPM]":"121.5","Cell RNA - HUVEC TERT2 [nTPM]":"139.0","Cell RNA - JURKAT [nTPM]":"44.0","Cell RNA - K-562 [nTPM]":"72.0","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"62.9","Cell RNA - MCF7 [nTPM]":"91.0","Cell RNA - MOLT-4 [nTPM]":"0.9","Cell RNA - NB-4 [nTPM]":"0.7","Cell RNA - NTERA-2 [nTPM]":"43.2","Cell RNA - OE19 [nTPM]":"113.2","Cell RNA - PC-3 [nTPM]":"90.3","Cell RNA - REH [nTPM]":"46.8","Cell RNA - RH-30 [nTPM]":"60.9","Cell RNA - RPMI-8226 [nTPM]":"1.5","Cell RNA - RPTEC TERT1 [nTPM]":"97.7","Cell RNA - RT4 [nTPM]":"117.3","Cell RNA - SCLC-21H [nTPM]":"43.9","Cell RNA - SH-SY5Y [nTPM]":"54.8","Cell RNA - SiHa [nTPM]":"79.0","Cell RNA - SK-BR-3 [nTPM]":"25.0","Cell RNA - SK-MEL-30 [nTPM]":"52.0","Cell RNA - SuSa [nTPM]":"97.2","Cell RNA - T-47d [nTPM]":"59.2","Cell RNA - THP-1 [nTPM]":"1.2","Cell RNA - TIME [nTPM]":"84.9","Cell RNA - U-138 MG [nTPM]":"45.2","Cell RNA - U-2 OS [nTPM]":"85.5","Cell RNA - U-2197 [nTPM]":"54.0","Cell RNA - U-251 MG [nTPM]":"58.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"3.4","Cell RNA - U-87 MG [nTPM]":"58.7","Cell RNA - U-937 [nTPM]":"0.6","Cell RNA - WM-115 [nTPM]":"62.9","Blood RNA - basophil [nTPM]":"1.6","Blood RNA - classical monocyte [nTPM]":"3.3","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"1.4","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"5.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"4.5","Blood RNA - naive B-cell [nTPM]":"6.3","Blood RNA - naive CD4 T-cell [nTPM]":"4.4","Blood RNA - naive CD8 T-cell [nTPM]":"1.6","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"4.7","Blood RNA - non-classical monocyte [nTPM]":"0.8","Blood RNA - plasmacytoid DC [nTPM]":"6.1","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"3.9","Brain RNA - amygdala [nTPM]":"83.8","Brain RNA - basal ganglia [nTPM]":"115.1","Brain RNA - cerebellum [nTPM]":"62.4","Brain RNA - cerebral cortex [nTPM]":"99.9","Brain RNA - hippocampal formation [nTPM]":"84.5","Brain RNA - hypothalamus [nTPM]":"77.3","Brain RNA - medulla oblongata [nTPM]":"79.1","Brain RNA - midbrain [nTPM]":"87.6","Brain RNA - pons [nTPM]":"81.0","Brain RNA - spinal cord [nTPM]":"67.6","Brain RNA - thalamus [nTPM]":"86.7","Brain RNA - white matter [nTPM]":"154.5","Single Cell Type RNA - Adipocytes [nTPM]":"71.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"33.1","Single Cell Type RNA - Astrocytes [nTPM]":"295.2","Single Cell Type RNA - B-cells [nTPM]":"20.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"33.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"70.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"36.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"64.9","Single Cell Type RNA - Bipolar cells [nTPM]":"55.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"29.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"32.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"55.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"60.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"37.0","Single Cell Type RNA - dendritic cells [nTPM]":"8.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"27.2","Single Cell Type RNA - Early spermatids [nTPM]":"68.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"29.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"43.3","Single Cell Type RNA - Endothelial cells [nTPM]":"54.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"25.8","Single Cell Type RNA - Erythroid cells [nTPM]":"8.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"584.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"53.7","Single Cell Type RNA - Fibroblasts [nTPM]":"37.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"37.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"46.5","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"84.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"37.5","Single Cell Type RNA - Hepatocytes [nTPM]":"15.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.1","Single Cell Type RNA - Horizontal cells [nTPM]":"67.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"263.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.0","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"15.2","Single Cell Type RNA - Langerhans cells [nTPM]":"15.9","Single Cell Type RNA - Late spermatids [nTPM]":"38.8","Single Cell Type RNA - Leydig cells [nTPM]":"23.9","Single Cell Type RNA - Macrophages [nTPM]":"19.4","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"159.3","Single Cell Type RNA - monocytes [nTPM]":"3.9","Single Cell Type RNA - Muller glia cells [nTPM]":"40.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"353.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"791.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"43.1","Single Cell Type RNA - Paneth cells [nTPM]":"23.5","Single Cell Type RNA - Peritubular cells [nTPM]":"21.8","Single Cell Type RNA - Plasma cells [nTPM]":"1.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"82.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"29.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"25.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"55.0","Single Cell Type RNA - Sertoli cells [nTPM]":"98.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"32.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"128.4","Single Cell Type RNA - Spermatocytes [nTPM]":"88.9","Single Cell Type RNA - Spermatogonia [nTPM]":"65.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"42.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"25.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"33.2","Single Cell Type RNA - T-cells [nTPM]":"3.4","Single Cell Type RNA - Theca cells [nTPM]":"67.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.1","Single Cell Type RNA - Urothelial cells [nTPM]":"87.3"},{"Gene":"PTPN11","Gene synonym":["BPTP3","NS1","PTP2C","SH-PTP2","SHP-2","SHP2"],"Ensembl":"ENSG00000179295","Gene description":"Protein tyrosine phosphatase non-receptor type 11","Uniprot":["Q06124"],"Chromosome":"12","Position":"112418351-112509918","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":["Cancer-related genes","Deafness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005377"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli rim","Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"74000","Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Nucleoplasm","Nucleoli rim"],"Subcellular additional location":["Actin filaments","Cytosol"],"Antibody RRID":{"CAB005377":"AB_632401"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Tissue RNA - adipose tissue [nTPM]":"62.9","Tissue RNA - adrenal gland [nTPM]":"36.6","Tissue RNA - amygdala [nTPM]":"74.6","Tissue RNA - appendix [nTPM]":"34.7","Tissue RNA - basal ganglia [nTPM]":"91.7","Tissue RNA - bone marrow [nTPM]":"46.3","Tissue RNA - breast [nTPM]":"37.6","Tissue RNA - cerebellum [nTPM]":"72.7","Tissue RNA - cerebral cortex [nTPM]":"115.7","Tissue RNA - cervix [nTPM]":"37.9","Tissue RNA - choroid plexus [nTPM]":"38.4","Tissue RNA - colon [nTPM]":"32.5","Tissue RNA - duodenum [nTPM]":"27.6","Tissue RNA - endometrium 1 [nTPM]":"37.8","Tissue RNA - epididymis [nTPM]":"28.7","Tissue RNA - esophagus [nTPM]":"38.9","Tissue RNA - fallopian tube [nTPM]":"24.3","Tissue RNA - gallbladder [nTPM]":"29.4","Tissue RNA - heart muscle [nTPM]":"68.7","Tissue RNA - hippocampal formation [nTPM]":"66.1","Tissue RNA - hypothalamus [nTPM]":"85.6","Tissue RNA - kidney [nTPM]":"39.7","Tissue RNA - liver [nTPM]":"53.0","Tissue RNA - lung [nTPM]":"34.4","Tissue RNA - lymph node [nTPM]":"35.6","Tissue RNA - medulla oblongata [nTPM]":"79.0","Tissue RNA - midbrain [nTPM]":"84.1","Tissue RNA - ovary [nTPM]":"26.2","Tissue RNA - pancreas [nTPM]":"31.6","Tissue RNA - parathyroid gland [nTPM]":"53.4","Tissue RNA - pituitary gland [nTPM]":"16.1","Tissue RNA - placenta [nTPM]":"38.0","Tissue RNA - pons [nTPM]":"85.7","Tissue RNA - prostate [nTPM]":"35.2","Tissue RNA - rectum [nTPM]":"30.6","Tissue RNA - retina [nTPM]":"51.8","Tissue RNA - salivary gland [nTPM]":"25.9","Tissue RNA - seminal vesicle [nTPM]":"42.4","Tissue RNA - skeletal muscle [nTPM]":"75.1","Tissue RNA - skin 1 [nTPM]":"32.1","Tissue RNA - small intestine [nTPM]":"26.1","Tissue RNA - smooth muscle [nTPM]":"45.7","Tissue RNA - spinal cord [nTPM]":"83.4","Tissue RNA - spleen [nTPM]":"26.7","Tissue RNA - stomach 1 [nTPM]":"30.4","Tissue RNA - testis [nTPM]":"18.2","Tissue RNA - thalamus [nTPM]":"81.7","Tissue RNA - thymus [nTPM]":"35.5","Tissue RNA - thyroid gland [nTPM]":"46.8","Tissue RNA - tongue [nTPM]":"64.0","Tissue RNA - tonsil [nTPM]":"32.5","Tissue RNA - urinary bladder [nTPM]":"40.1","Tissue RNA - vagina [nTPM]":"23.5","Tissue RNA - white matter [nTPM]":"106.3","Cell RNA - A-431 [nTPM]":"116.9","Cell RNA - A549 [nTPM]":"107.6","Cell RNA - AF22 [nTPM]":"77.0","Cell RNA - AN3-CA [nTPM]":"73.4","Cell RNA - ASC diff [nTPM]":"109.7","Cell RNA - ASC TERT1 [nTPM]":"106.1","Cell RNA - BEWO [nTPM]":"92.7","Cell RNA - BJ [nTPM]":"136.4","Cell RNA - BJ hTERT+ [nTPM]":"148.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"105.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"78.5","Cell RNA - CACO-2 [nTPM]":"107.7","Cell RNA - CAPAN-2 [nTPM]":"43.4","Cell RNA - Daudi [nTPM]":"124.5","Cell RNA - EFO-21 [nTPM]":"69.4","Cell RNA - fHDF\/TERT166 [nTPM]":"127.4","Cell RNA - GAMG [nTPM]":"66.7","Cell RNA - HaCaT [nTPM]":"68.1","Cell RNA - HAP1 [nTPM]":"100.1","Cell RNA - HBEC3-KT [nTPM]":"121.6","Cell RNA - HBF TERT88 [nTPM]":"173.8","Cell RNA - HDLM-2 [nTPM]":"93.1","Cell RNA - HEK 293 [nTPM]":"85.0","Cell RNA - HEL [nTPM]":"181.5","Cell RNA - HeLa [nTPM]":"102.6","Cell RNA - Hep G2 [nTPM]":"59.8","Cell RNA - HHSteC [nTPM]":"109.2","Cell RNA - HL-60 [nTPM]":"145.8","Cell RNA - HMC-1 [nTPM]":"108.0","Cell RNA - HSkMC [nTPM]":"86.6","Cell RNA - hTCEpi [nTPM]":"119.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"113.6","Cell RNA - hTERT-HME1 [nTPM]":"159.8","Cell RNA - hTERT-RPE1 [nTPM]":"101.3","Cell RNA - HUVEC TERT2 [nTPM]":"88.7","Cell RNA - JURKAT [nTPM]":"92.0","Cell RNA - K-562 [nTPM]":"140.2","Cell RNA - Karpas-707 [nTPM]":"41.3","Cell RNA - LHCN-M2 [nTPM]":"103.3","Cell RNA - MCF7 [nTPM]":"83.2","Cell RNA - MOLT-4 [nTPM]":"101.0","Cell RNA - NB-4 [nTPM]":"69.7","Cell RNA - NTERA-2 [nTPM]":"94.1","Cell RNA - OE19 [nTPM]":"112.3","Cell RNA - PC-3 [nTPM]":"73.4","Cell RNA - REH [nTPM]":"102.4","Cell RNA - RH-30 [nTPM]":"114.6","Cell RNA - RPMI-8226 [nTPM]":"70.5","Cell RNA - RPTEC TERT1 [nTPM]":"97.3","Cell RNA - RT4 [nTPM]":"126.7","Cell RNA - SCLC-21H [nTPM]":"53.3","Cell RNA - SH-SY5Y [nTPM]":"66.1","Cell RNA - SiHa [nTPM]":"133.7","Cell RNA - SK-BR-3 [nTPM]":"99.8","Cell RNA - SK-MEL-30 [nTPM]":"85.2","Cell RNA - SuSa [nTPM]":"77.6","Cell RNA - T-47d [nTPM]":"114.8","Cell RNA - THP-1 [nTPM]":"97.8","Cell RNA - TIME [nTPM]":"108.1","Cell RNA - U-138 MG [nTPM]":"122.9","Cell RNA - U-2 OS [nTPM]":"110.0","Cell RNA - U-2197 [nTPM]":"74.2","Cell RNA - U-251 MG [nTPM]":"121.8","Cell RNA - U-266\/70 [nTPM]":"79.4","Cell RNA - U-266\/84 [nTPM]":"141.6","Cell RNA - U-698 [nTPM]":"120.2","Cell RNA - U-87 MG [nTPM]":"102.2","Cell RNA - U-937 [nTPM]":"99.7","Cell RNA - WM-115 [nTPM]":"117.7","Blood RNA - basophil [nTPM]":"32.2","Blood RNA - classical monocyte [nTPM]":"11.7","Blood RNA - eosinophil [nTPM]":"16.8","Blood RNA - gdT-cell [nTPM]":"14.8","Blood RNA - intermediate monocyte [nTPM]":"10.2","Blood RNA - MAIT T-cell [nTPM]":"14.0","Blood RNA - memory B-cell [nTPM]":"18.1","Blood RNA - memory CD4 T-cell [nTPM]":"13.3","Blood RNA - memory CD8 T-cell [nTPM]":"12.4","Blood RNA - myeloid DC [nTPM]":"13.6","Blood RNA - naive B-cell [nTPM]":"20.8","Blood RNA - naive CD4 T-cell [nTPM]":"15.3","Blood RNA - naive CD8 T-cell [nTPM]":"11.9","Blood RNA - neutrophil [nTPM]":"10.7","Blood RNA - NK-cell [nTPM]":"12.6","Blood RNA - non-classical monocyte [nTPM]":"13.7","Blood RNA - plasmacytoid DC [nTPM]":"18.3","Blood RNA - T-reg [nTPM]":"10.9","Blood RNA - total PBMC [nTPM]":"7.2","Brain RNA - amygdala [nTPM]":"74.6","Brain RNA - basal ganglia [nTPM]":"91.7","Brain RNA - cerebellum [nTPM]":"72.7","Brain RNA - cerebral cortex [nTPM]":"115.7","Brain RNA - hippocampal formation [nTPM]":"66.1","Brain RNA - hypothalamus [nTPM]":"85.6","Brain RNA - medulla oblongata [nTPM]":"79.0","Brain RNA - midbrain [nTPM]":"84.1","Brain RNA - pons [nTPM]":"85.7","Brain RNA - spinal cord [nTPM]":"83.4","Brain RNA - thalamus [nTPM]":"81.7","Brain RNA - white matter [nTPM]":"106.3","Single Cell Type RNA - Adipocytes [nTPM]":"49.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"68.2","Single Cell Type RNA - Astrocytes [nTPM]":"27.7","Single Cell Type RNA - B-cells [nTPM]":"25.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"25.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"39.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"25.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"20.5","Single Cell Type RNA - Bipolar cells [nTPM]":"29.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"40.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"32.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"131.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"41.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.5","Single Cell Type RNA - dendritic cells [nTPM]":"34.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"25.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"37.5","Single Cell Type RNA - Early spermatids [nTPM]":"63.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"31.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"92.6","Single Cell Type RNA - Endothelial cells [nTPM]":"46.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"21.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"67.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"42.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"25.3","Single Cell Type RNA - Fibroblasts [nTPM]":"35.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"40.9","Single Cell Type RNA - granulocytes [nTPM]":"28.4","Single Cell Type RNA - Granulosa cells [nTPM]":"33.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.0","Single Cell Type RNA - Hepatocytes [nTPM]":"101.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"26.8","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"54.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"22.0","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"33.3","Single Cell Type RNA - Langerhans cells [nTPM]":"21.6","Single Cell Type RNA - Late spermatids [nTPM]":"28.5","Single Cell Type RNA - Leydig cells [nTPM]":"51.6","Single Cell Type RNA - Macrophages [nTPM]":"31.8","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"40.3","Single Cell Type RNA - monocytes [nTPM]":"31.1","Single Cell Type RNA - Muller glia cells [nTPM]":"59.8","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"32.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"73.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"59.3","Single Cell Type RNA - Paneth cells [nTPM]":"19.6","Single Cell Type RNA - Peritubular cells [nTPM]":"79.7","Single Cell Type RNA - Plasma cells [nTPM]":"37.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"73.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"16.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"39.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"22.2","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"58.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"49.2","Single Cell Type RNA - Spermatocytes [nTPM]":"7.1","Single Cell Type RNA - Spermatogonia [nTPM]":"6.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"37.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"35.2","Single Cell Type RNA - T-cells [nTPM]":"31.7","Single Cell Type RNA - Theca cells [nTPM]":"30.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"22.2","Single Cell Type RNA - Urothelial cells [nTPM]":"66.8"},{"Gene":"PTPN14","Gene synonym":["PEZ"],"Ensembl":"ENSG00000152104","Gene description":"Protein tyrosine phosphatase non-receptor type 14","Uniprot":["Q15678"],"Chromosome":"1","Position":"214348700-214552449","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Microglial cells":"91.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011469","HPA053864","CAB069441"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB011469":"AB_299202","CAB069441":null,"HPA053864":"AB_2682281"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.29e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.16e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-3"},"Tissue RNA - adipose tissue [nTPM]":"7.5","Tissue RNA - adrenal gland [nTPM]":"8.0","Tissue RNA - amygdala [nTPM]":"3.7","Tissue RNA - appendix [nTPM]":"1.8","Tissue RNA - basal ganglia [nTPM]":"1.5","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"10.6","Tissue RNA - cerebellum [nTPM]":"1.5","Tissue RNA - cerebral cortex [nTPM]":"3.7","Tissue RNA - cervix [nTPM]":"5.2","Tissue RNA - choroid plexus [nTPM]":"13.4","Tissue RNA - colon [nTPM]":"7.6","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"8.2","Tissue RNA - epididymis [nTPM]":"2.5","Tissue RNA - esophagus [nTPM]":"6.0","Tissue RNA - fallopian tube [nTPM]":"7.3","Tissue RNA - gallbladder [nTPM]":"3.3","Tissue RNA - heart muscle [nTPM]":"6.0","Tissue RNA - hippocampal formation [nTPM]":"3.3","Tissue RNA - hypothalamus [nTPM]":"0.8","Tissue RNA - kidney [nTPM]":"8.2","Tissue RNA - liver [nTPM]":"0.7","Tissue RNA - lung [nTPM]":"4.6","Tissue RNA - lymph node [nTPM]":"1.3","Tissue RNA - medulla oblongata [nTPM]":"2.4","Tissue RNA - midbrain [nTPM]":"2.4","Tissue RNA - ovary [nTPM]":"6.6","Tissue RNA - pancreas [nTPM]":"4.3","Tissue RNA - parathyroid gland [nTPM]":"3.3","Tissue RNA - pituitary gland [nTPM]":"1.8","Tissue RNA - placenta [nTPM]":"7.8","Tissue RNA - pons [nTPM]":"2.1","Tissue RNA - prostate [nTPM]":"6.7","Tissue RNA - rectum [nTPM]":"2.3","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"6.5","Tissue RNA - seminal vesicle [nTPM]":"6.6","Tissue RNA - skeletal muscle [nTPM]":"19.8","Tissue RNA - skin 1 [nTPM]":"16.2","Tissue RNA - small intestine [nTPM]":"2.8","Tissue RNA - smooth muscle [nTPM]":"7.9","Tissue RNA - spinal cord [nTPM]":"1.4","Tissue RNA - spleen [nTPM]":"3.5","Tissue RNA - stomach 1 [nTPM]":"4.5","Tissue RNA - testis [nTPM]":"3.9","Tissue RNA - thalamus [nTPM]":"4.2","Tissue RNA - thymus [nTPM]":"2.1","Tissue RNA - thyroid gland [nTPM]":"5.3","Tissue RNA - tongue [nTPM]":"10.2","Tissue RNA - tonsil [nTPM]":"1.8","Tissue RNA - urinary bladder [nTPM]":"5.6","Tissue RNA - vagina [nTPM]":"5.6","Tissue RNA - white matter [nTPM]":"1.9","Cell RNA - A-431 [nTPM]":"21.1","Cell RNA - A549 [nTPM]":"9.2","Cell RNA - AF22 [nTPM]":"7.2","Cell RNA - AN3-CA [nTPM]":"10.6","Cell RNA - ASC diff [nTPM]":"12.3","Cell RNA - ASC TERT1 [nTPM]":"20.9","Cell RNA - BEWO [nTPM]":"21.6","Cell RNA - BJ [nTPM]":"23.2","Cell RNA - BJ hTERT+ [nTPM]":"21.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.4","Cell RNA - CACO-2 [nTPM]":"18.8","Cell RNA - CAPAN-2 [nTPM]":"10.7","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"25.3","Cell RNA - fHDF\/TERT166 [nTPM]":"53.6","Cell RNA - GAMG [nTPM]":"10.0","Cell RNA - HaCaT [nTPM]":"18.1","Cell RNA - HAP1 [nTPM]":"10.0","Cell RNA - HBEC3-KT [nTPM]":"25.7","Cell RNA - HBF TERT88 [nTPM]":"29.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"7.7","Cell RNA - HEL [nTPM]":"1.9","Cell RNA - HeLa [nTPM]":"26.6","Cell RNA - Hep G2 [nTPM]":"3.5","Cell RNA - HHSteC [nTPM]":"22.2","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"1.0","Cell RNA - HSkMC [nTPM]":"15.6","Cell RNA - hTCEpi [nTPM]":"26.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"30.0","Cell RNA - hTERT-HME1 [nTPM]":"47.4","Cell RNA - hTERT-RPE1 [nTPM]":"28.1","Cell RNA - HUVEC TERT2 [nTPM]":"33.8","Cell RNA - JURKAT [nTPM]":"0.6","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"41.8","Cell RNA - MCF7 [nTPM]":"2.3","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"16.2","Cell RNA - OE19 [nTPM]":"3.7","Cell RNA - PC-3 [nTPM]":"9.9","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"36.3","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"30.6","Cell RNA - RT4 [nTPM]":"10.5","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"1.7","Cell RNA - SiHa [nTPM]":"28.7","Cell RNA - SK-BR-3 [nTPM]":"18.4","Cell RNA - SK-MEL-30 [nTPM]":"11.6","Cell RNA - SuSa [nTPM]":"25.1","Cell RNA - T-47d [nTPM]":"18.4","Cell RNA - THP-1 [nTPM]":"0.7","Cell RNA - TIME [nTPM]":"61.4","Cell RNA - U-138 MG [nTPM]":"40.3","Cell RNA - U-2 OS [nTPM]":"15.9","Cell RNA - U-2197 [nTPM]":"14.6","Cell RNA - U-251 MG [nTPM]":"33.3","Cell RNA - U-266\/70 [nTPM]":"1.2","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"21.6","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"34.6","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.7","Brain RNA - basal ganglia [nTPM]":"1.5","Brain RNA - cerebellum [nTPM]":"1.5","Brain RNA - cerebral cortex [nTPM]":"3.7","Brain RNA - hippocampal formation [nTPM]":"3.3","Brain RNA - hypothalamus [nTPM]":"0.8","Brain RNA - medulla oblongata [nTPM]":"2.4","Brain RNA - midbrain [nTPM]":"2.4","Brain RNA - pons [nTPM]":"2.1","Brain RNA - spinal cord [nTPM]":"1.4","Brain RNA - thalamus [nTPM]":"4.2","Brain RNA - white matter [nTPM]":"1.9","Single Cell Type RNA - Adipocytes [nTPM]":"60.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"73.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.6","Single Cell Type RNA - Astrocytes [nTPM]":"47.3","Single Cell Type RNA - B-cells [nTPM]":"1.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"56.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"39.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"45.5","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"20.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"29.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"20.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"32.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"38.8","Single Cell Type RNA - dendritic cells [nTPM]":"1.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"12.9","Single Cell Type RNA - Early spermatids [nTPM]":"8.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"42.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"25.9","Single Cell Type RNA - Endothelial cells [nTPM]":"53.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.5","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"47.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.2","Single Cell Type RNA - Fibroblasts [nTPM]":"20.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"55.2","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"13.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"40.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.1","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"1.5","Single Cell Type RNA - Langerhans cells [nTPM]":"7.7","Single Cell Type RNA - Late spermatids [nTPM]":"4.4","Single Cell Type RNA - Leydig cells [nTPM]":"26.1","Single Cell Type RNA - Macrophages [nTPM]":"2.4","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"91.8","Single Cell Type RNA - monocytes [nTPM]":"0.3","Single Cell Type RNA - Muller glia cells [nTPM]":"3.9","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"39.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"31.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"29.3","Single Cell Type RNA - Plasma cells [nTPM]":"1.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.3","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"38.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.2","Single Cell Type RNA - Spermatogonia [nTPM]":"10.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"36.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"24.2","Single Cell Type RNA - T-cells [nTPM]":"3.7","Single Cell Type RNA - Theca cells [nTPM]":"46.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.9","Single Cell Type RNA - Urothelial cells [nTPM]":"28.9"},{"Gene":"PTPN22","Gene synonym":["Lyp","Lyp1","Lyp2","PTPN8"],"Ensembl":"ENSG00000134242","Gene description":"Protein tyrosine phosphatase non-receptor type 22","Uniprot":["Q9Y2R2"],"Chromosome":"1","Position":"113813811-113871753","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Autophagy","Immunity"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":["Diabetes mellitus","Disease variant","Systemic lupus erythematosus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"38.0","lymphoid tissue":"20.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"B-cells":"67.4","dendritic cells":"176.0","NK-cells":"108.1","Plasma cells":"79.6","T-cells":"151.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"69.3","HL-60":"27.7","U-266\/70":"29.2","U-698":"37.5","U-937":"28.4"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"11","RNA mouse brain regional specific nTPM":{"cerebellum":"5.3"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004912","CAB012209","HPA013350"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles","Plasma membrane"],"Antibody RRID":{"CAB012209":null,"HPA004912":"AB_10602069","HPA013350":"AB_10601570"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.0","Tissue RNA - adrenal gland [nTPM]":"1.5","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"11.5","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"38.0","Tissue RNA - breast [nTPM]":"2.3","Tissue RNA - cerebellum [nTPM]":"0.4","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"1.8","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"4.0","Tissue RNA - duodenum [nTPM]":"6.4","Tissue RNA - endometrium 1 [nTPM]":"1.0","Tissue RNA - epididymis [nTPM]":"1.1","Tissue RNA - esophagus [nTPM]":"1.7","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"4.8","Tissue RNA - heart muscle [nTPM]":"0.6","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"2.0","Tissue RNA - lung [nTPM]":"7.5","Tissue RNA - lymph node [nTPM]":"20.3","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"1.3","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"0.8","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"1.0","Tissue RNA - rectum [nTPM]":"4.3","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"1.3","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"8.6","Tissue RNA - smooth muscle [nTPM]":"1.6","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"13.2","Tissue RNA - stomach 1 [nTPM]":"5.2","Tissue RNA - testis [nTPM]":"1.4","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"20.0","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"13.5","Tissue RNA - urinary bladder [nTPM]":"4.2","Tissue RNA - vagina [nTPM]":"0.9","Tissue RNA - white matter [nTPM]":"0.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.9","Cell RNA - BJ hTERT+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.7","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"69.3","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.5","Cell RNA - HDLM-2 [nTPM]":"6.5","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"10.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"27.7","Cell RNA - HMC-1 [nTPM]":"21.1","Cell RNA - HSkMC [nTPM]":"5.7","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.8","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"5.1","Cell RNA - HUVEC TERT2 [nTPM]":"10.6","Cell RNA - JURKAT [nTPM]":"17.2","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"15.7","Cell RNA - LHCN-M2 [nTPM]":"10.3","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"20.1","Cell RNA - NB-4 [nTPM]":"15.7","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"1.2","Cell RNA - RH-30 [nTPM]":"6.7","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.5","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"10.0","Cell RNA - TIME [nTPM]":"5.0","Cell RNA - U-138 MG [nTPM]":"16.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.5","Cell RNA - U-266\/70 [nTPM]":"29.2","Cell RNA - U-266\/84 [nTPM]":"6.6","Cell RNA - U-698 [nTPM]":"37.5","Cell RNA - U-87 MG [nTPM]":"11.1","Cell RNA - U-937 [nTPM]":"28.4","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"15.8","Blood RNA - classical monocyte [nTPM]":"4.8","Blood RNA - eosinophil [nTPM]":"25.0","Blood RNA - gdT-cell [nTPM]":"17.0","Blood RNA - intermediate monocyte [nTPM]":"1.3","Blood RNA - MAIT T-cell [nTPM]":"20.1","Blood RNA - memory B-cell [nTPM]":"9.9","Blood RNA - memory CD4 T-cell [nTPM]":"8.4","Blood RNA - memory CD8 T-cell [nTPM]":"13.6","Blood RNA - myeloid DC [nTPM]":"8.7","Blood RNA - naive B-cell [nTPM]":"7.4","Blood RNA - naive CD4 T-cell [nTPM]":"5.0","Blood RNA - naive CD8 T-cell [nTPM]":"12.1","Blood RNA - neutrophil [nTPM]":"2.4","Blood RNA - NK-cell [nTPM]":"11.0","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"5.2","Blood RNA - T-reg [nTPM]":"14.5","Blood RNA - total PBMC [nTPM]":"7.3","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.4","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"0.8","Single Cell Type RNA - Adipocytes [nTPM]":"2.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"67.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"176.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"1.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"16.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"2.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.0","Single Cell Type RNA - granulocytes [nTPM]":"27.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"17.3","Single Cell Type RNA - Langerhans cells [nTPM]":"26.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"26.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"14.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"108.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"79.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"151.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"PTPN23","Gene synonym":["DKFZP564F0923","HD-PTP","KIAA1471"],"Ensembl":"ENSG00000076201","Gene description":"Protein tyrosine phosphatase non-receptor type 23","Uniprot":["Q9H3S7"],"Chromosome":"3","Position":"47381011-47413435","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation","Protein transport","Transport"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016845"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies","Vesicles"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA016845":"AB_1855926"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.82e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Tissue RNA - adipose tissue [nTPM]":"18.5","Tissue RNA - adrenal gland [nTPM]":"19.1","Tissue RNA - amygdala [nTPM]":"6.2","Tissue RNA - appendix [nTPM]":"12.6","Tissue RNA - basal ganglia [nTPM]":"9.2","Tissue RNA - bone marrow [nTPM]":"14.7","Tissue RNA - breast [nTPM]":"17.4","Tissue RNA - cerebellum [nTPM]":"5.8","Tissue RNA - cerebral cortex [nTPM]":"10.5","Tissue RNA - cervix [nTPM]":"23.3","Tissue RNA - choroid plexus [nTPM]":"5.1","Tissue RNA - colon [nTPM]":"16.3","Tissue RNA - duodenum [nTPM]":"14.3","Tissue RNA - endometrium 1 [nTPM]":"20.9","Tissue RNA - epididymis [nTPM]":"7.5","Tissue RNA - esophagus [nTPM]":"19.0","Tissue RNA - fallopian tube [nTPM]":"19.2","Tissue RNA - gallbladder [nTPM]":"8.4","Tissue RNA - heart muscle [nTPM]":"13.2","Tissue RNA - hippocampal formation [nTPM]":"7.1","Tissue RNA - hypothalamus [nTPM]":"7.2","Tissue RNA - kidney [nTPM]":"17.5","Tissue RNA - liver [nTPM]":"14.0","Tissue RNA - lung [nTPM]":"18.7","Tissue RNA - lymph node [nTPM]":"9.1","Tissue RNA - medulla oblongata [nTPM]":"8.8","Tissue RNA - midbrain [nTPM]":"7.2","Tissue RNA - ovary [nTPM]":"23.5","Tissue RNA - pancreas [nTPM]":"20.2","Tissue RNA - parathyroid gland [nTPM]":"23.5","Tissue RNA - pituitary gland [nTPM]":"30.9","Tissue RNA - placenta [nTPM]":"11.6","Tissue RNA - pons [nTPM]":"8.5","Tissue RNA - prostate [nTPM]":"18.7","Tissue RNA - rectum [nTPM]":"6.5","Tissue RNA - retina [nTPM]":"8.5","Tissue RNA - salivary gland [nTPM]":"20.0","Tissue RNA - seminal vesicle [nTPM]":"11.4","Tissue RNA - skeletal muscle [nTPM]":"30.0","Tissue RNA - skin 1 [nTPM]":"26.4","Tissue RNA - small intestine [nTPM]":"18.4","Tissue RNA - smooth muscle [nTPM]":"8.8","Tissue RNA - spinal cord [nTPM]":"5.5","Tissue RNA - spleen [nTPM]":"20.0","Tissue RNA - stomach 1 [nTPM]":"16.1","Tissue RNA - testis [nTPM]":"15.6","Tissue RNA - thalamus [nTPM]":"7.7","Tissue RNA - thymus [nTPM]":"8.0","Tissue RNA - thyroid gland [nTPM]":"27.1","Tissue RNA - tongue [nTPM]":"8.9","Tissue RNA - tonsil [nTPM]":"7.3","Tissue RNA - urinary bladder [nTPM]":"18.5","Tissue RNA - vagina [nTPM]":"20.4","Tissue RNA - white matter [nTPM]":"14.4","Cell RNA - A-431 [nTPM]":"21.5","Cell RNA - A549 [nTPM]":"29.9","Cell RNA - AF22 [nTPM]":"16.4","Cell RNA - AN3-CA [nTPM]":"21.4","Cell RNA - ASC diff [nTPM]":"21.0","Cell RNA - ASC TERT1 [nTPM]":"16.0","Cell RNA - BEWO [nTPM]":"15.8","Cell RNA - BJ [nTPM]":"19.2","Cell RNA - BJ hTERT+ [nTPM]":"18.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.8","Cell RNA - CACO-2 [nTPM]":"25.0","Cell RNA - CAPAN-2 [nTPM]":"20.7","Cell RNA - Daudi [nTPM]":"15.1","Cell RNA - EFO-21 [nTPM]":"17.2","Cell RNA - fHDF\/TERT166 [nTPM]":"21.9","Cell RNA - GAMG [nTPM]":"31.2","Cell RNA - HaCaT [nTPM]":"19.0","Cell RNA - HAP1 [nTPM]":"14.3","Cell RNA - HBEC3-KT [nTPM]":"20.8","Cell RNA - HBF TERT88 [nTPM]":"8.5","Cell RNA - HDLM-2 [nTPM]":"14.3","Cell RNA - HEK 293 [nTPM]":"15.1","Cell RNA - HEL [nTPM]":"21.0","Cell RNA - HeLa [nTPM]":"22.2","Cell RNA - Hep G2 [nTPM]":"24.0","Cell RNA - HHSteC [nTPM]":"23.0","Cell RNA - HL-60 [nTPM]":"12.3","Cell RNA - HMC-1 [nTPM]":"27.5","Cell RNA - HSkMC [nTPM]":"21.4","Cell RNA - hTCEpi [nTPM]":"20.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.9","Cell RNA - hTERT-HME1 [nTPM]":"23.2","Cell RNA - hTERT-RPE1 [nTPM]":"12.4","Cell RNA - HUVEC TERT2 [nTPM]":"21.7","Cell RNA - JURKAT [nTPM]":"12.5","Cell RNA - K-562 [nTPM]":"15.9","Cell RNA - Karpas-707 [nTPM]":"20.3","Cell RNA - LHCN-M2 [nTPM]":"19.0","Cell RNA - MCF7 [nTPM]":"30.2","Cell RNA - MOLT-4 [nTPM]":"11.5","Cell RNA - NB-4 [nTPM]":"10.4","Cell RNA - NTERA-2 [nTPM]":"17.5","Cell RNA - OE19 [nTPM]":"14.9","Cell RNA - PC-3 [nTPM]":"20.1","Cell RNA - REH [nTPM]":"7.2","Cell RNA - RH-30 [nTPM]":"7.9","Cell RNA - RPMI-8226 [nTPM]":"18.5","Cell RNA - RPTEC TERT1 [nTPM]":"13.2","Cell RNA - RT4 [nTPM]":"40.9","Cell RNA - SCLC-21H [nTPM]":"8.6","Cell RNA - SH-SY5Y [nTPM]":"20.6","Cell RNA - SiHa [nTPM]":"17.1","Cell RNA - SK-BR-3 [nTPM]":"35.6","Cell RNA - SK-MEL-30 [nTPM]":"13.6","Cell RNA - SuSa [nTPM]":"9.8","Cell RNA - T-47d [nTPM]":"20.3","Cell RNA - THP-1 [nTPM]":"12.0","Cell RNA - TIME [nTPM]":"22.4","Cell RNA - U-138 MG [nTPM]":"26.7","Cell RNA - U-2 OS [nTPM]":"22.2","Cell RNA - U-2197 [nTPM]":"37.7","Cell RNA - U-251 MG [nTPM]":"27.5","Cell RNA - U-266\/70 [nTPM]":"28.8","Cell RNA - U-266\/84 [nTPM]":"20.4","Cell RNA - U-698 [nTPM]":"8.7","Cell RNA - U-87 MG [nTPM]":"29.0","Cell RNA - U-937 [nTPM]":"11.6","Cell RNA - WM-115 [nTPM]":"19.5","Blood RNA - basophil [nTPM]":"0.8","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"6.2","Brain RNA - basal ganglia [nTPM]":"9.2","Brain RNA - cerebellum [nTPM]":"5.8","Brain RNA - cerebral cortex [nTPM]":"10.5","Brain RNA - hippocampal formation [nTPM]":"7.1","Brain RNA - hypothalamus [nTPM]":"7.2","Brain RNA - medulla oblongata [nTPM]":"8.8","Brain RNA - midbrain [nTPM]":"7.2","Brain RNA - pons [nTPM]":"8.5","Brain RNA - spinal cord [nTPM]":"5.5","Brain RNA - thalamus [nTPM]":"7.7","Brain RNA - white matter [nTPM]":"14.4","Single Cell Type RNA - Adipocytes [nTPM]":"11.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.0","Single Cell Type RNA - Astrocytes [nTPM]":"17.0","Single Cell Type RNA - B-cells [nTPM]":"8.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"11.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"9.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.6","Single Cell Type RNA - dendritic cells [nTPM]":"11.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"10.5","Single Cell Type RNA - Early spermatids [nTPM]":"2.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.7","Single Cell Type RNA - Endothelial cells [nTPM]":"12.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.3","Single Cell Type RNA - Erythroid cells [nTPM]":"2.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.9","Single Cell Type RNA - Fibroblasts [nTPM]":"9.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"26.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.1","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"14.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.4","Single Cell Type RNA - Hepatocytes [nTPM]":"12.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.9","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.3","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"10.4","Single Cell Type RNA - Langerhans cells [nTPM]":"5.5","Single Cell Type RNA - Late spermatids [nTPM]":"3.1","Single Cell Type RNA - Leydig cells [nTPM]":"19.3","Single Cell Type RNA - Macrophages [nTPM]":"9.5","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"8.7","Single Cell Type RNA - Muller glia cells [nTPM]":"8.8","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.5","Single Cell Type RNA - Paneth cells [nTPM]":"10.4","Single Cell Type RNA - Peritubular cells [nTPM]":"13.5","Single Cell Type RNA - Plasma cells [nTPM]":"15.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.8","Single Cell Type RNA - Spermatocytes [nTPM]":"13.6","Single Cell Type RNA - Spermatogonia [nTPM]":"13.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.3","Single Cell Type RNA - T-cells [nTPM]":"8.9","Single Cell Type RNA - Theca cells [nTPM]":"9.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.8","Single Cell Type RNA - Urothelial cells [nTPM]":"8.2"},{"Gene":"PTPRC","Gene synonym":["CD45","GP180","LCA","T200"],"Ensembl":"ENSG00000081237","Gene description":"Protein tyrosine phosphatase receptor type C","Uniprot":["P08575"],"Chromosome":"1","Position":"198638457-198757476","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":["Cancer-related genes","Disease variant","SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"208.6","lymphoid tissue":"329.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"525.2","dendritic cells":"1026.4","Macrophages":"534.1","monocytes":"554.9","NK-cells":"769.3","Plasma cells":"474.2","T-cells":"1049.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"209.9","HEL":"118.0","HL-60":"108.1","JURKAT":"266.4","MOLT-4":"161.1","THP-1":"87.0","U-266\/70":"93.7","U-266\/84":"91.2","U-698":"123.4","U-937":"94.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000052","HPA000440","CAB002800","CAB056154","CAB068221"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"24000000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB000052":"AB_2314143","CAB002800":"AB_2237910","CAB056154":"AB_2665572","CAB068221":"AB_2665571","HPA000440":"AB_611377"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.42e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-2"},"Tissue RNA - adipose tissue [nTPM]":"32.8","Tissue RNA - adrenal gland [nTPM]":"11.6","Tissue RNA - amygdala [nTPM]":"3.8","Tissue RNA - appendix [nTPM]":"248.5","Tissue RNA - basal ganglia [nTPM]":"3.3","Tissue RNA - bone marrow [nTPM]":"208.6","Tissue RNA - breast [nTPM]":"13.9","Tissue RNA - cerebellum [nTPM]":"4.4","Tissue RNA - cerebral cortex [nTPM]":"4.3","Tissue RNA - cervix [nTPM]":"14.9","Tissue RNA - choroid plexus [nTPM]":"6.9","Tissue RNA - colon [nTPM]":"26.4","Tissue RNA - duodenum [nTPM]":"27.4","Tissue RNA - endometrium 1 [nTPM]":"11.3","Tissue RNA - epididymis [nTPM]":"5.6","Tissue RNA - esophagus [nTPM]":"15.1","Tissue RNA - fallopian tube [nTPM]":"8.4","Tissue RNA - gallbladder [nTPM]":"45.7","Tissue RNA - heart muscle [nTPM]":"7.3","Tissue RNA - hippocampal formation [nTPM]":"3.5","Tissue RNA - hypothalamus [nTPM]":"5.6","Tissue RNA - kidney [nTPM]":"7.0","Tissue RNA - liver [nTPM]":"29.6","Tissue RNA - lung [nTPM]":"68.6","Tissue RNA - lymph node [nTPM]":"329.9","Tissue RNA - medulla oblongata [nTPM]":"12.9","Tissue RNA - midbrain [nTPM]":"8.6","Tissue RNA - ovary [nTPM]":"5.7","Tissue RNA - pancreas [nTPM]":"5.6","Tissue RNA - parathyroid gland [nTPM]":"4.0","Tissue RNA - pituitary gland [nTPM]":"2.9","Tissue RNA - placenta [nTPM]":"23.5","Tissue RNA - pons [nTPM]":"11.5","Tissue RNA - prostate [nTPM]":"11.6","Tissue RNA - rectum [nTPM]":"30.5","Tissue RNA - retina [nTPM]":"2.0","Tissue RNA - salivary gland [nTPM]":"13.8","Tissue RNA - seminal vesicle [nTPM]":"6.6","Tissue RNA - skeletal muscle [nTPM]":"4.6","Tissue RNA - skin 1 [nTPM]":"5.7","Tissue RNA - small intestine [nTPM]":"42.9","Tissue RNA - smooth muscle [nTPM]":"25.3","Tissue RNA - spinal cord [nTPM]":"7.9","Tissue RNA - spleen [nTPM]":"202.5","Tissue RNA - stomach 1 [nTPM]":"37.9","Tissue RNA - testis [nTPM]":"5.5","Tissue RNA - thalamus [nTPM]":"6.9","Tissue RNA - thymus [nTPM]":"306.9","Tissue RNA - thyroid gland [nTPM]":"7.0","Tissue RNA - tongue [nTPM]":"7.6","Tissue RNA - tonsil [nTPM]":"251.2","Tissue RNA - urinary bladder [nTPM]":"62.1","Tissue RNA - vagina [nTPM]":"5.2","Tissue RNA - white matter [nTPM]":"14.7","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.8","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"209.9","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.7","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"0.6","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"118.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"108.1","Cell RNA - HMC-1 [nTPM]":"0.7","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.3","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.5","Cell RNA - JURKAT [nTPM]":"266.4","Cell RNA - K-562 [nTPM]":"2.4","Cell RNA - Karpas-707 [nTPM]":"3.3","Cell RNA - LHCN-M2 [nTPM]":"0.3","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"161.1","Cell RNA - NB-4 [nTPM]":"65.0","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"4.6","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"1.2","Cell RNA - SH-SY5Y [nTPM]":"1.8","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"0.5","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"87.0","Cell RNA - TIME [nTPM]":"1.3","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"0.8","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"93.7","Cell RNA - U-266\/84 [nTPM]":"91.2","Cell RNA - U-698 [nTPM]":"123.4","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"94.5","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"226.1","Blood RNA - classical monocyte [nTPM]":"480.0","Blood RNA - eosinophil [nTPM]":"521.4","Blood RNA - gdT-cell [nTPM]":"634.4","Blood RNA - intermediate monocyte [nTPM]":"885.8","Blood RNA - MAIT T-cell [nTPM]":"541.8","Blood RNA - memory B-cell [nTPM]":"249.0","Blood RNA - memory CD4 T-cell [nTPM]":"437.0","Blood RNA - memory CD8 T-cell [nTPM]":"618.1","Blood RNA - myeloid DC [nTPM]":"385.8","Blood RNA - naive B-cell [nTPM]":"245.8","Blood RNA - naive CD4 T-cell [nTPM]":"489.8","Blood RNA - naive CD8 T-cell [nTPM]":"494.1","Blood RNA - neutrophil [nTPM]":"844.3","Blood RNA - NK-cell [nTPM]":"506.9","Blood RNA - non-classical monocyte [nTPM]":"1015.8","Blood RNA - plasmacytoid DC [nTPM]":"57.4","Blood RNA - T-reg [nTPM]":"508.6","Blood RNA - total PBMC [nTPM]":"1340.6","Brain RNA - amygdala [nTPM]":"3.8","Brain RNA - basal ganglia [nTPM]":"3.3","Brain RNA - cerebellum [nTPM]":"4.4","Brain RNA - cerebral cortex [nTPM]":"4.3","Brain RNA - hippocampal formation [nTPM]":"3.5","Brain RNA - hypothalamus [nTPM]":"5.6","Brain RNA - medulla oblongata [nTPM]":"12.9","Brain RNA - midbrain [nTPM]":"8.6","Brain RNA - pons [nTPM]":"11.5","Brain RNA - spinal cord [nTPM]":"7.9","Brain RNA - thalamus [nTPM]":"6.9","Brain RNA - white matter [nTPM]":"14.7","Single Cell Type RNA - Adipocytes [nTPM]":"12.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"62.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"525.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"14.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.6","Single Cell Type RNA - dendritic cells [nTPM]":"1026.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.7","Single Cell Type RNA - Early spermatids [nTPM]":"2.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.3","Single Cell Type RNA - Endothelial cells [nTPM]":"15.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"58.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.9","Single Cell Type RNA - Fibroblasts [nTPM]":"17.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"46.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.7","Single Cell Type RNA - granulocytes [nTPM]":"246.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"6.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"96.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"334.9","Single Cell Type RNA - Langerhans cells [nTPM]":"214.5","Single Cell Type RNA - Late spermatids [nTPM]":"3.5","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"534.1","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"201.4","Single Cell Type RNA - monocytes [nTPM]":"554.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"769.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"474.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"1049.1","Single Cell Type RNA - Theca cells [nTPM]":"5.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.9","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"PTPRF","Gene synonym":["LAR"],"Ensembl":"ENSG00000142949","Gene description":"Protein tyrosine phosphatase receptor type F","Uniprot":["P10586"],"Chromosome":"1","Position":"43525187-43623666","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Heparin-binding","Hydrolase","Protein phosphatase","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"259.9","Extravillous trophoblasts":"290.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SK-BR-3":"314.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012710"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"160000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA012710":"AB_1855933"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.47e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.03e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Tissue RNA - adipose tissue [nTPM]":"91.7","Tissue RNA - adrenal gland [nTPM]":"11.9","Tissue RNA - amygdala [nTPM]":"47.1","Tissue RNA - appendix [nTPM]":"14.0","Tissue RNA - basal ganglia [nTPM]":"48.4","Tissue RNA - bone marrow [nTPM]":"1.8","Tissue RNA - breast [nTPM]":"57.4","Tissue RNA - cerebellum [nTPM]":"22.3","Tissue RNA - cerebral cortex [nTPM]":"45.6","Tissue RNA - cervix [nTPM]":"36.3","Tissue RNA - choroid plexus [nTPM]":"4.7","Tissue RNA - colon [nTPM]":"79.5","Tissue RNA - duodenum [nTPM]":"70.5","Tissue RNA - endometrium 1 [nTPM]":"28.0","Tissue RNA - epididymis [nTPM]":"71.9","Tissue RNA - esophagus [nTPM]":"101.7","Tissue RNA - fallopian tube [nTPM]":"70.5","Tissue RNA - gallbladder [nTPM]":"30.4","Tissue RNA - heart muscle [nTPM]":"7.6","Tissue RNA - hippocampal formation [nTPM]":"45.3","Tissue RNA - hypothalamus [nTPM]":"39.9","Tissue RNA - kidney [nTPM]":"27.7","Tissue RNA - liver [nTPM]":"107.2","Tissue RNA - lung [nTPM]":"35.4","Tissue RNA - lymph node [nTPM]":"4.7","Tissue RNA - medulla oblongata [nTPM]":"33.1","Tissue RNA - midbrain [nTPM]":"43.6","Tissue RNA - ovary [nTPM]":"22.1","Tissue RNA - pancreas [nTPM]":"56.8","Tissue RNA - parathyroid gland [nTPM]":"31.1","Tissue RNA - pituitary gland [nTPM]":"23.5","Tissue RNA - placenta [nTPM]":"55.7","Tissue RNA - pons [nTPM]":"33.1","Tissue RNA - prostate [nTPM]":"67.3","Tissue RNA - rectum [nTPM]":"51.4","Tissue RNA - retina [nTPM]":"24.7","Tissue RNA - salivary gland [nTPM]":"101.7","Tissue RNA - seminal vesicle [nTPM]":"43.1","Tissue RNA - skeletal muscle [nTPM]":"2.7","Tissue RNA - skin 1 [nTPM]":"107.9","Tissue RNA - small intestine [nTPM]":"78.5","Tissue RNA - smooth muscle [nTPM]":"35.0","Tissue RNA - spinal cord [nTPM]":"30.4","Tissue RNA - spleen [nTPM]":"4.0","Tissue RNA - stomach 1 [nTPM]":"49.7","Tissue RNA - testis [nTPM]":"9.4","Tissue RNA - thalamus [nTPM]":"45.6","Tissue RNA - thymus [nTPM]":"29.6","Tissue RNA - thyroid gland [nTPM]":"23.8","Tissue RNA - tongue [nTPM]":"3.4","Tissue RNA - tonsil [nTPM]":"26.2","Tissue RNA - urinary bladder [nTPM]":"40.0","Tissue RNA - vagina [nTPM]":"51.2","Tissue RNA - white matter [nTPM]":"37.4","Cell RNA - A-431 [nTPM]":"165.6","Cell RNA - A549 [nTPM]":"76.5","Cell RNA - AF22 [nTPM]":"49.0","Cell RNA - AN3-CA [nTPM]":"58.0","Cell RNA - ASC diff [nTPM]":"11.2","Cell RNA - ASC TERT1 [nTPM]":"0.6","Cell RNA - BEWO [nTPM]":"274.3","Cell RNA - BJ [nTPM]":"92.1","Cell RNA - BJ hTERT+ [nTPM]":"36.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"73.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"62.6","Cell RNA - CACO-2 [nTPM]":"82.0","Cell RNA - CAPAN-2 [nTPM]":"214.9","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"25.6","Cell RNA - fHDF\/TERT166 [nTPM]":"40.2","Cell RNA - GAMG [nTPM]":"59.2","Cell RNA - HaCaT [nTPM]":"124.7","Cell RNA - HAP1 [nTPM]":"57.5","Cell RNA - HBEC3-KT [nTPM]":"200.7","Cell RNA - HBF TERT88 [nTPM]":"89.1","Cell RNA - HDLM-2 [nTPM]":"2.0","Cell RNA - HEK 293 [nTPM]":"72.1","Cell RNA - HEL [nTPM]":"1.0","Cell RNA - HeLa [nTPM]":"48.7","Cell RNA - Hep G2 [nTPM]":"75.3","Cell RNA - HHSteC [nTPM]":"33.8","Cell RNA - HL-60 [nTPM]":"1.2","Cell RNA - HMC-1 [nTPM]":"1.3","Cell RNA - HSkMC [nTPM]":"11.3","Cell RNA - hTCEpi [nTPM]":"113.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"106.4","Cell RNA - hTERT-HME1 [nTPM]":"174.9","Cell RNA - hTERT-RPE1 [nTPM]":"92.6","Cell RNA - HUVEC TERT2 [nTPM]":"111.5","Cell RNA - JURKAT [nTPM]":"7.7","Cell RNA - K-562 [nTPM]":"25.4","Cell RNA - Karpas-707 [nTPM]":"7.1","Cell RNA - LHCN-M2 [nTPM]":"27.5","Cell RNA - MCF7 [nTPM]":"94.0","Cell RNA - MOLT-4 [nTPM]":"1.2","Cell RNA - NB-4 [nTPM]":"1.3","Cell RNA - NTERA-2 [nTPM]":"75.9","Cell RNA - OE19 [nTPM]":"89.8","Cell RNA - PC-3 [nTPM]":"21.0","Cell RNA - REH [nTPM]":"57.2","Cell RNA - RH-30 [nTPM]":"86.9","Cell RNA - RPMI-8226 [nTPM]":"3.7","Cell RNA - RPTEC TERT1 [nTPM]":"28.3","Cell RNA - RT4 [nTPM]":"241.5","Cell RNA - SCLC-21H [nTPM]":"73.3","Cell RNA - SH-SY5Y [nTPM]":"28.0","Cell RNA - SiHa [nTPM]":"90.8","Cell RNA - SK-BR-3 [nTPM]":"314.0","Cell RNA - SK-MEL-30 [nTPM]":"11.8","Cell RNA - SuSa [nTPM]":"128.8","Cell RNA - T-47d [nTPM]":"91.5","Cell RNA - THP-1 [nTPM]":"17.3","Cell RNA - TIME [nTPM]":"88.2","Cell RNA - U-138 MG [nTPM]":"1.6","Cell RNA - U-2 OS [nTPM]":"116.5","Cell RNA - U-2197 [nTPM]":"7.5","Cell RNA - U-251 MG [nTPM]":"126.1","Cell RNA - U-266\/70 [nTPM]":"3.1","Cell RNA - U-266\/84 [nTPM]":"2.7","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"7.4","Cell RNA - U-937 [nTPM]":"3.9","Cell RNA - WM-115 [nTPM]":"233.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"47.1","Brain RNA - basal ganglia [nTPM]":"48.4","Brain RNA - cerebellum [nTPM]":"22.3","Brain RNA - cerebral cortex [nTPM]":"45.6","Brain RNA - hippocampal formation [nTPM]":"45.3","Brain RNA - hypothalamus [nTPM]":"39.9","Brain RNA - medulla oblongata [nTPM]":"33.1","Brain RNA - midbrain [nTPM]":"43.6","Brain RNA - pons [nTPM]":"33.1","Brain RNA - spinal cord [nTPM]":"30.4","Brain RNA - thalamus [nTPM]":"45.6","Brain RNA - white matter [nTPM]":"37.4","Single Cell Type RNA - Adipocytes [nTPM]":"2.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"157.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"101.1","Single Cell Type RNA - Astrocytes [nTPM]":"39.2","Single Cell Type RNA - B-cells [nTPM]":"2.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"62.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"51.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"67.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"52.9","Single Cell Type RNA - Bipolar cells [nTPM]":"33.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"146.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"102.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"130.1","Single Cell Type RNA - Club cells [nTPM]":"74.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"86.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"43.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"64.3","Single Cell Type RNA - dendritic cells [nTPM]":"1.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"259.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"147.4","Single Cell Type RNA - Early spermatids [nTPM]":"4.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"80.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.2","Single Cell Type RNA - Endothelial cells [nTPM]":"7.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"100.9","Single Cell Type RNA - Erythroid cells [nTPM]":"8.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"40.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"120.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"290.1","Single Cell Type RNA - Fibroblasts [nTPM]":"19.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"93.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"70.6","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"72.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.4","Single Cell Type RNA - Hepatocytes [nTPM]":"159.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.1","Single Cell Type RNA - Horizontal cells [nTPM]":"185.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"16.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"171.7","Single Cell Type RNA - Ionocytes [nTPM]":"50.8","Single Cell Type RNA - Kupffer cells [nTPM]":"4.9","Single Cell Type RNA - Langerhans cells [nTPM]":"5.8","Single Cell Type RNA - Late spermatids [nTPM]":"8.5","Single Cell Type RNA - Leydig cells [nTPM]":"6.8","Single Cell Type RNA - Macrophages [nTPM]":"3.4","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"2.9","Single Cell Type RNA - Muller glia cells [nTPM]":"27.2","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"68.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"165.0","Single Cell Type RNA - Paneth cells [nTPM]":"124.7","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"1.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"68.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"208.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"128.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"31.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.5","Single Cell Type RNA - Spermatocytes [nTPM]":"9.0","Single Cell Type RNA - Spermatogonia [nTPM]":"37.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"107.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"91.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"66.2","Single Cell Type RNA - T-cells [nTPM]":"3.9","Single Cell Type RNA - Theca cells [nTPM]":"9.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"142.5","Single Cell Type RNA - Urothelial cells [nTPM]":"78.7"},{"Gene":"PTPRN2","Gene synonym":["IA-2beta","ICAAR","KIAA0387","phogrin"],"Ensembl":"ENSG00000155093","Gene description":"Protein tyrosine phosphatase receptor type N2","Uniprot":["Q92932"],"Chromosome":"7","Position":"157539056-158587823","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid metabolism","Phospholipid metabolism"],"Molecular function":["Hydrolase","Protein phosphatase","Receptor"],"Disease involvement":["Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"49.9","pancreas":"98.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Enteroendocrine cells":"131.1","Excitatory neurons":"439.6","Inhibitory neurons":"433.4","Oligodendrocyte precursor cells":"138.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"40.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"23.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"23.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"45.5","HDLM-2":"42.0","MOLT-4":"22.1","NB-4":"43.0","SCLC-21H":"23.8","SH-SY5Y":"25.4","U-87 MG":"27.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006900","HPA007255","HPA026656"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1600000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA006900":"AB_1079715","HPA007255":null,"HPA026656":"AB_1855912"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.37e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.68e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.8","Tissue RNA - adrenal gland [nTPM]":"16.5","Tissue RNA - amygdala [nTPM]":"29.4","Tissue RNA - appendix [nTPM]":"2.7","Tissue RNA - basal ganglia [nTPM]":"34.3","Tissue RNA - bone marrow [nTPM]":"1.3","Tissue RNA - breast [nTPM]":"2.9","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"49.9","Tissue RNA - cervix [nTPM]":"2.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"7.7","Tissue RNA - duodenum [nTPM]":"8.3","Tissue RNA - endometrium 1 [nTPM]":"3.0","Tissue RNA - epididymis [nTPM]":"4.2","Tissue RNA - esophagus [nTPM]":"1.9","Tissue RNA - fallopian tube [nTPM]":"10.8","Tissue RNA - gallbladder [nTPM]":"7.6","Tissue RNA - heart muscle [nTPM]":"3.1","Tissue RNA - hippocampal formation [nTPM]":"35.2","Tissue RNA - hypothalamus [nTPM]":"22.7","Tissue RNA - kidney [nTPM]":"3.9","Tissue RNA - liver [nTPM]":"1.6","Tissue RNA - lung [nTPM]":"4.8","Tissue RNA - lymph node [nTPM]":"3.4","Tissue RNA - medulla oblongata [nTPM]":"7.9","Tissue RNA - midbrain [nTPM]":"3.1","Tissue RNA - ovary [nTPM]":"8.7","Tissue RNA - pancreas [nTPM]":"98.1","Tissue RNA - parathyroid gland [nTPM]":"1.0","Tissue RNA - pituitary gland [nTPM]":"41.0","Tissue RNA - placenta [nTPM]":"2.1","Tissue RNA - pons [nTPM]":"3.4","Tissue RNA - prostate [nTPM]":"17.3","Tissue RNA - rectum [nTPM]":"6.1","Tissue RNA - retina [nTPM]":"9.2","Tissue RNA - salivary gland [nTPM]":"12.9","Tissue RNA - seminal vesicle [nTPM]":"3.6","Tissue RNA - skeletal muscle [nTPM]":"1.2","Tissue RNA - skin 1 [nTPM]":"0.8","Tissue RNA - small intestine [nTPM]":"6.7","Tissue RNA - smooth muscle [nTPM]":"2.1","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"13.4","Tissue RNA - stomach 1 [nTPM]":"40.2","Tissue RNA - testis [nTPM]":"6.2","Tissue RNA - thalamus [nTPM]":"14.1","Tissue RNA - thymus [nTPM]":"1.6","Tissue RNA - thyroid gland [nTPM]":"8.7","Tissue RNA - tongue [nTPM]":"1.9","Tissue RNA - tonsil [nTPM]":"2.5","Tissue RNA - urinary bladder [nTPM]":"4.2","Tissue RNA - vagina [nTPM]":"2.1","Tissue RNA - white matter [nTPM]":"20.5","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"45.5","Cell RNA - AN3-CA [nTPM]":"3.6","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.4","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"4.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.5","Cell RNA - GAMG [nTPM]":"9.4","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"1.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"42.0","Cell RNA - HEK 293 [nTPM]":"0.8","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"7.3","Cell RNA - HHSteC [nTPM]":"1.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"2.0","Cell RNA - hTCEpi [nTPM]":"0.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.5","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"3.4","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.7","Cell RNA - MOLT-4 [nTPM]":"22.1","Cell RNA - NB-4 [nTPM]":"43.0","Cell RNA - NTERA-2 [nTPM]":"5.7","Cell RNA - OE19 [nTPM]":"13.7","Cell RNA - PC-3 [nTPM]":"3.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"2.7","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"23.8","Cell RNA - SH-SY5Y [nTPM]":"25.4","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"20.9","Cell RNA - TIME [nTPM]":"6.2","Cell RNA - U-138 MG [nTPM]":"9.2","Cell RNA - U-2 OS [nTPM]":"4.3","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"1.5","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"27.7","Cell RNA - U-937 [nTPM]":"17.4","Cell RNA - WM-115 [nTPM]":"6.8","Blood RNA - basophil [nTPM]":"14.1","Blood RNA - classical monocyte [nTPM]":"1.5","Blood RNA - eosinophil [nTPM]":"2.8","Blood RNA - gdT-cell [nTPM]":"1.3","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"3.5","Blood RNA - memory CD4 T-cell [nTPM]":"2.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"2.1","Blood RNA - naive B-cell [nTPM]":"4.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.4","Blood RNA - naive CD8 T-cell [nTPM]":"1.4","Blood RNA - neutrophil [nTPM]":"23.6","Blood RNA - NK-cell [nTPM]":"2.4","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"5.3","Blood RNA - total PBMC [nTPM]":"1.3","Brain RNA - amygdala [nTPM]":"29.4","Brain RNA - basal ganglia [nTPM]":"34.3","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"49.9","Brain RNA - hippocampal formation [nTPM]":"35.2","Brain RNA - hypothalamus [nTPM]":"22.7","Brain RNA - medulla oblongata [nTPM]":"7.9","Brain RNA - midbrain [nTPM]":"3.1","Brain RNA - pons [nTPM]":"3.4","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"14.1","Brain RNA - white matter [nTPM]":"20.5","Single Cell Type RNA - Adipocytes [nTPM]":"40.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.9","Single Cell Type RNA - Astrocytes [nTPM]":"16.3","Single Cell Type RNA - B-cells [nTPM]":"18.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"30.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"9.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"8.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"22.9","Single Cell Type RNA - Early spermatids [nTPM]":"51.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.5","Single Cell Type RNA - Endothelial cells [nTPM]":"26.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"131.1","Single Cell Type RNA - Erythroid cells [nTPM]":"6.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"439.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"13.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"41.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.8","Single Cell Type RNA - granulocytes [nTPM]":"19.0","Single Cell Type RNA - Granulosa cells [nTPM]":"14.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"44.3","Single Cell Type RNA - Hepatocytes [nTPM]":"0.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"44.5","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"433.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"43.3","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"7.0","Single Cell Type RNA - Langerhans cells [nTPM]":"11.3","Single Cell Type RNA - Late spermatids [nTPM]":"19.3","Single Cell Type RNA - Leydig cells [nTPM]":"12.5","Single Cell Type RNA - Macrophages [nTPM]":"7.9","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"27.2","Single Cell Type RNA - monocytes [nTPM]":"5.7","Single Cell Type RNA - Muller glia cells [nTPM]":"67.3","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"138.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.3","Single Cell Type RNA - Paneth cells [nTPM]":"7.0","Single Cell Type RNA - Peritubular cells [nTPM]":"19.5","Single Cell Type RNA - Plasma cells [nTPM]":"5.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"52.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.0","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.0","Single Cell Type RNA - Spermatocytes [nTPM]":"62.8","Single Cell Type RNA - Spermatogonia [nTPM]":"16.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"14.8","Single Cell Type RNA - Theca cells [nTPM]":"32.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.7","Single Cell Type RNA - Urothelial cells [nTPM]":"24.8"},{"Gene":"PTPRO","Gene synonym":["GLEPP1","NPHS6","PTP-oc","PTP-U2","PTPU2"],"Ensembl":"ENSG00000151490","Gene description":"Protein tyrosine phosphatase receptor type O","Uniprot":["Q16827"],"Chromosome":"12","Position":"15322257-15602175","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protein phosphatase","Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"26.8","kidney":"36.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Excitatory neurons":"193.6","Inhibitory neurons":"231.1","Oligodendrocyte precursor cells":"126.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"8.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"GAMG":"9.9","NTERA-2":"5.8","SH-SY5Y":"6.1","THP-1":"2.7"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"olfactory bulb":"175.9"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034525"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA034525":"AB_10669785"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.8","Tissue RNA - adrenal gland [nTPM]":"0.8","Tissue RNA - amygdala [nTPM]":"8.7","Tissue RNA - appendix [nTPM]":"3.0","Tissue RNA - basal ganglia [nTPM]":"9.4","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"0.8","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"10.3","Tissue RNA - cervix [nTPM]":"1.3","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"10.4","Tissue RNA - duodenum [nTPM]":"1.7","Tissue RNA - endometrium 1 [nTPM]":"4.8","Tissue RNA - epididymis [nTPM]":"1.4","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"1.0","Tissue RNA - gallbladder [nTPM]":"1.2","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"9.8","Tissue RNA - hypothalamus [nTPM]":"8.9","Tissue RNA - kidney [nTPM]":"36.3","Tissue RNA - liver [nTPM]":"1.3","Tissue RNA - lung [nTPM]":"6.8","Tissue RNA - lymph node [nTPM]":"3.1","Tissue RNA - medulla oblongata [nTPM]":"2.2","Tissue RNA - midbrain [nTPM]":"3.3","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"2.4","Tissue RNA - placenta [nTPM]":"4.4","Tissue RNA - pons [nTPM]":"5.3","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"26.8","Tissue RNA - retina [nTPM]":"7.5","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"0.8","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"2.0","Tissue RNA - smooth muscle [nTPM]":"6.6","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"3.4","Tissue RNA - stomach 1 [nTPM]":"0.8","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"9.5","Tissue RNA - thymus [nTPM]":"1.2","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.5","Tissue RNA - tonsil [nTPM]":"3.2","Tissue RNA - urinary bladder [nTPM]":"1.5","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"2.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.3","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"9.9","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.6","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.5","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"5.8","Cell RNA - OE19 [nTPM]":"1.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"1.5","Cell RNA - SH-SY5Y [nTPM]":"6.1","Cell RNA - SiHa [nTPM]":"0.9","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"2.7","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"1.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"6.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"12.3","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"8.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.7","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"8.5","Blood RNA - naive B-cell [nTPM]":"8.6","Blood RNA - naive CD4 T-cell [nTPM]":"2.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.2","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"12.7","Blood RNA - plasmacytoid DC [nTPM]":"10.9","Blood RNA - T-reg [nTPM]":"1.4","Blood RNA - total PBMC [nTPM]":"3.2","Brain RNA - amygdala [nTPM]":"8.7","Brain RNA - basal ganglia [nTPM]":"9.4","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"10.3","Brain RNA - hippocampal formation [nTPM]":"9.8","Brain RNA - hypothalamus [nTPM]":"8.9","Brain RNA - medulla oblongata [nTPM]":"2.2","Brain RNA - midbrain [nTPM]":"3.3","Brain RNA - pons [nTPM]":"5.3","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"9.5","Brain RNA - white matter [nTPM]":"2.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"7.5","Single Cell Type RNA - B-cells [nTPM]":"7.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"25.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"4.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"1.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"193.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"0.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"26.1","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"231.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"21.1","Single Cell Type RNA - Langerhans cells [nTPM]":"10.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"10.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"13.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.6","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"126.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"9.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"1.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"1.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"22.4","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"PTRH2","Gene synonym":["BIT1","CFAP37","CGI-147","PTH2"],"Ensembl":"ENSG00000141378","Gene description":"Peptidyl-tRNA hydrolase 2","Uniprot":["Q9Y3E5"],"Chromosome":"17","Position":"59674636-59707626","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012897"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA012897":"AB_1855949"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.50e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.59e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.01e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Tissue RNA - adipose tissue [nTPM]":"20.8","Tissue RNA - adrenal gland [nTPM]":"25.9","Tissue RNA - amygdala [nTPM]":"24.3","Tissue RNA - appendix [nTPM]":"17.3","Tissue RNA - basal ganglia [nTPM]":"25.1","Tissue RNA - bone marrow [nTPM]":"14.5","Tissue RNA - breast [nTPM]":"27.6","Tissue RNA - cerebellum [nTPM]":"25.0","Tissue RNA - cerebral cortex [nTPM]":"31.9","Tissue RNA - cervix [nTPM]":"19.7","Tissue RNA - choroid plexus [nTPM]":"23.6","Tissue RNA - colon [nTPM]":"24.1","Tissue RNA - duodenum [nTPM]":"15.3","Tissue RNA - endometrium 1 [nTPM]":"18.8","Tissue RNA - epididymis [nTPM]":"48.5","Tissue RNA - esophagus [nTPM]":"18.1","Tissue RNA - fallopian tube [nTPM]":"18.4","Tissue RNA - gallbladder [nTPM]":"18.2","Tissue RNA - heart muscle [nTPM]":"14.5","Tissue RNA - hippocampal formation [nTPM]":"25.1","Tissue RNA - hypothalamus [nTPM]":"26.1","Tissue RNA - kidney [nTPM]":"18.5","Tissue RNA - liver [nTPM]":"45.7","Tissue RNA - lung [nTPM]":"14.7","Tissue RNA - lymph node [nTPM]":"19.0","Tissue RNA - medulla oblongata [nTPM]":"25.9","Tissue RNA - midbrain [nTPM]":"26.1","Tissue RNA - ovary [nTPM]":"16.9","Tissue RNA - pancreas [nTPM]":"19.5","Tissue RNA - parathyroid gland [nTPM]":"18.6","Tissue RNA - pituitary gland [nTPM]":"14.1","Tissue RNA - placenta [nTPM]":"18.6","Tissue RNA - pons [nTPM]":"26.7","Tissue RNA - prostate [nTPM]":"20.7","Tissue RNA - rectum [nTPM]":"27.5","Tissue RNA - retina [nTPM]":"10.2","Tissue RNA - salivary gland [nTPM]":"15.9","Tissue RNA - seminal vesicle [nTPM]":"18.6","Tissue RNA - skeletal muscle [nTPM]":"25.0","Tissue RNA - skin 1 [nTPM]":"15.7","Tissue RNA - small intestine [nTPM]":"13.2","Tissue RNA - smooth muscle [nTPM]":"22.9","Tissue RNA - spinal cord [nTPM]":"24.8","Tissue RNA - spleen [nTPM]":"17.5","Tissue RNA - stomach 1 [nTPM]":"16.1","Tissue RNA - testis [nTPM]":"19.5","Tissue RNA - thalamus [nTPM]":"24.9","Tissue RNA - thymus [nTPM]":"17.3","Tissue RNA - thyroid gland [nTPM]":"16.2","Tissue RNA - tongue [nTPM]":"20.9","Tissue RNA - tonsil [nTPM]":"24.1","Tissue RNA - urinary bladder [nTPM]":"44.0","Tissue RNA - vagina [nTPM]":"11.8","Tissue RNA - white matter [nTPM]":"27.4","Cell RNA - A-431 [nTPM]":"75.9","Cell RNA - A549 [nTPM]":"142.9","Cell RNA - AF22 [nTPM]":"44.3","Cell RNA - AN3-CA [nTPM]":"40.8","Cell RNA - ASC diff [nTPM]":"84.8","Cell RNA - ASC TERT1 [nTPM]":"72.6","Cell RNA - BEWO [nTPM]":"47.4","Cell RNA - BJ [nTPM]":"70.6","Cell RNA - BJ hTERT+ [nTPM]":"63.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"60.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"89.0","Cell RNA - CACO-2 [nTPM]":"94.1","Cell RNA - CAPAN-2 [nTPM]":"57.7","Cell RNA - Daudi [nTPM]":"54.1","Cell RNA - EFO-21 [nTPM]":"105.0","Cell RNA - fHDF\/TERT166 [nTPM]":"60.9","Cell RNA - GAMG [nTPM]":"101.1","Cell RNA - HaCaT [nTPM]":"73.3","Cell RNA - HAP1 [nTPM]":"98.4","Cell RNA - HBEC3-KT [nTPM]":"93.8","Cell RNA - HBF TERT88 [nTPM]":"89.4","Cell RNA - HDLM-2 [nTPM]":"104.2","Cell RNA - HEK 293 [nTPM]":"133.2","Cell RNA - HEL [nTPM]":"96.7","Cell RNA - HeLa [nTPM]":"72.3","Cell RNA - Hep G2 [nTPM]":"176.2","Cell RNA - HHSteC [nTPM]":"129.4","Cell RNA - HL-60 [nTPM]":"86.0","Cell RNA - HMC-1 [nTPM]":"52.5","Cell RNA - HSkMC [nTPM]":"82.0","Cell RNA - hTCEpi [nTPM]":"120.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"93.9","Cell RNA - hTERT-HME1 [nTPM]":"108.5","Cell RNA - hTERT-RPE1 [nTPM]":"42.8","Cell RNA - HUVEC TERT2 [nTPM]":"102.5","Cell RNA - JURKAT [nTPM]":"37.4","Cell RNA - K-562 [nTPM]":"111.3","Cell RNA - Karpas-707 [nTPM]":"58.2","Cell RNA - LHCN-M2 [nTPM]":"92.4","Cell RNA - MCF7 [nTPM]":"187.9","Cell RNA - MOLT-4 [nTPM]":"74.2","Cell RNA - NB-4 [nTPM]":"71.2","Cell RNA - NTERA-2 [nTPM]":"38.0","Cell RNA - OE19 [nTPM]":"194.5","Cell RNA - PC-3 [nTPM]":"113.4","Cell RNA - REH [nTPM]":"39.1","Cell RNA - RH-30 [nTPM]":"74.8","Cell RNA - RPMI-8226 [nTPM]":"80.7","Cell RNA - RPTEC TERT1 [nTPM]":"103.7","Cell RNA - RT4 [nTPM]":"109.2","Cell RNA - SCLC-21H [nTPM]":"57.9","Cell RNA - SH-SY5Y [nTPM]":"74.2","Cell RNA - SiHa [nTPM]":"36.7","Cell RNA - SK-BR-3 [nTPM]":"39.6","Cell RNA - SK-MEL-30 [nTPM]":"91.5","Cell RNA - SuSa [nTPM]":"50.7","Cell RNA - T-47d [nTPM]":"93.1","Cell RNA - THP-1 [nTPM]":"61.1","Cell RNA - TIME [nTPM]":"67.2","Cell RNA - U-138 MG [nTPM]":"77.8","Cell RNA - U-2 OS [nTPM]":"77.8","Cell RNA - U-2197 [nTPM]":"47.1","Cell RNA - U-251 MG [nTPM]":"77.9","Cell RNA - U-266\/70 [nTPM]":"73.6","Cell RNA - U-266\/84 [nTPM]":"91.9","Cell RNA - U-698 [nTPM]":"82.3","Cell RNA - U-87 MG [nTPM]":"50.7","Cell RNA - U-937 [nTPM]":"54.4","Cell RNA - WM-115 [nTPM]":"60.4","Blood RNA - basophil [nTPM]":"6.1","Blood RNA - classical monocyte [nTPM]":"69.0","Blood RNA - eosinophil [nTPM]":"2.9","Blood RNA - gdT-cell [nTPM]":"22.7","Blood RNA - intermediate monocyte [nTPM]":"67.4","Blood RNA - MAIT T-cell [nTPM]":"30.9","Blood RNA - memory B-cell [nTPM]":"43.1","Blood RNA - memory CD4 T-cell [nTPM]":"26.3","Blood RNA - memory CD8 T-cell [nTPM]":"25.7","Blood RNA - myeloid DC [nTPM]":"50.0","Blood RNA - naive B-cell [nTPM]":"33.1","Blood RNA - naive CD4 T-cell [nTPM]":"37.4","Blood RNA - naive CD8 T-cell [nTPM]":"27.0","Blood RNA - neutrophil [nTPM]":"29.0","Blood RNA - NK-cell [nTPM]":"34.8","Blood RNA - non-classical monocyte [nTPM]":"86.0","Blood RNA - plasmacytoid DC [nTPM]":"59.4","Blood RNA - T-reg [nTPM]":"34.0","Blood RNA - total PBMC [nTPM]":"37.9","Brain RNA - amygdala [nTPM]":"24.3","Brain RNA - basal ganglia [nTPM]":"25.1","Brain RNA - cerebellum [nTPM]":"25.0","Brain RNA - cerebral cortex [nTPM]":"31.9","Brain RNA - hippocampal formation [nTPM]":"25.1","Brain RNA - hypothalamus [nTPM]":"26.1","Brain RNA - medulla oblongata [nTPM]":"25.9","Brain RNA - midbrain [nTPM]":"26.1","Brain RNA - pons [nTPM]":"26.7","Brain RNA - spinal cord [nTPM]":"24.8","Brain RNA - thalamus [nTPM]":"24.9","Brain RNA - white matter [nTPM]":"27.4","Single Cell Type RNA - Adipocytes [nTPM]":"21.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.6","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"18.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"36.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"50.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"48.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"27.9","Single Cell Type RNA - Bipolar cells [nTPM]":"4.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"22.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"51.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"26.8","Single Cell Type RNA - dendritic cells [nTPM]":"13.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"27.2","Single Cell Type RNA - Early spermatids [nTPM]":"22.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"33.1","Single Cell Type RNA - Endothelial cells [nTPM]":"22.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"17.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"25.0","Single Cell Type RNA - Fibroblasts [nTPM]":"29.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.1","Single Cell Type RNA - granulocytes [nTPM]":"22.8","Single Cell Type RNA - Granulosa cells [nTPM]":"12.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.8","Single Cell Type RNA - Hepatocytes [nTPM]":"31.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.9","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.3","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"9.7","Single Cell Type RNA - Langerhans cells [nTPM]":"17.2","Single Cell Type RNA - Late spermatids [nTPM]":"12.0","Single Cell Type RNA - Leydig cells [nTPM]":"17.4","Single Cell Type RNA - Macrophages [nTPM]":"14.6","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"11.4","Single Cell Type RNA - Muller glia cells [nTPM]":"7.2","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"28.8","Single Cell Type RNA - Paneth cells [nTPM]":"12.3","Single Cell Type RNA - Peritubular cells [nTPM]":"9.8","Single Cell Type RNA - Plasma cells [nTPM]":"24.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"35.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.4","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"25.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.2","Single Cell Type RNA - Spermatocytes [nTPM]":"33.4","Single Cell Type RNA - Spermatogonia [nTPM]":"13.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"35.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"31.7","Single Cell Type RNA - T-cells [nTPM]":"12.6","Single Cell Type RNA - Theca cells [nTPM]":"22.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.7","Single Cell Type RNA - Urothelial cells [nTPM]":"37.5"},{"Gene":"PTS","Gene synonym":["PTPS"],"Ensembl":"ENSG00000150787","Gene description":"6-pyruvoyltetrahydropterin synthase","Uniprot":["Q03393"],"Chromosome":"11","Position":"112226367-112269955","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Tetrahydrobiopterin biosynthesis"],"Molecular function":["Lyase"],"Disease involvement":["Disease variant","Phenylketonuria"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001481"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 16: Pancreatic endocrine cells - Mixed function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA001481":"AB_1079716"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.66e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Tissue RNA - adipose tissue [nTPM]":"11.7","Tissue RNA - adrenal gland [nTPM]":"63.0","Tissue RNA - amygdala [nTPM]":"17.6","Tissue RNA - appendix [nTPM]":"10.2","Tissue RNA - basal ganglia [nTPM]":"18.7","Tissue RNA - bone marrow [nTPM]":"22.7","Tissue RNA - breast [nTPM]":"20.5","Tissue RNA - cerebellum [nTPM]":"20.2","Tissue RNA - cerebral cortex [nTPM]":"27.6","Tissue RNA - cervix [nTPM]":"17.5","Tissue RNA - choroid plexus [nTPM]":"20.2","Tissue RNA - colon [nTPM]":"18.9","Tissue RNA - duodenum [nTPM]":"15.0","Tissue RNA - endometrium 1 [nTPM]":"13.6","Tissue RNA - epididymis [nTPM]":"29.7","Tissue RNA - esophagus [nTPM]":"29.0","Tissue RNA - fallopian tube [nTPM]":"11.7","Tissue RNA - gallbladder [nTPM]":"20.6","Tissue RNA - heart muscle [nTPM]":"8.8","Tissue RNA - hippocampal formation [nTPM]":"16.5","Tissue RNA - hypothalamus [nTPM]":"25.1","Tissue RNA - kidney [nTPM]":"44.7","Tissue RNA - liver [nTPM]":"68.9","Tissue RNA - lung [nTPM]":"7.8","Tissue RNA - lymph node [nTPM]":"10.5","Tissue RNA - medulla oblongata [nTPM]":"23.1","Tissue RNA - midbrain [nTPM]":"26.1","Tissue RNA - ovary [nTPM]":"9.9","Tissue RNA - pancreas [nTPM]":"15.0","Tissue RNA - parathyroid gland [nTPM]":"29.0","Tissue RNA - pituitary gland [nTPM]":"32.8","Tissue RNA - placenta [nTPM]":"18.0","Tissue RNA - pons [nTPM]":"24.6","Tissue RNA - prostate [nTPM]":"21.1","Tissue RNA - rectum [nTPM]":"21.5","Tissue RNA - retina [nTPM]":"19.0","Tissue RNA - salivary gland [nTPM]":"17.5","Tissue RNA - seminal vesicle [nTPM]":"16.4","Tissue RNA - skeletal muscle [nTPM]":"18.5","Tissue RNA - skin 1 [nTPM]":"17.0","Tissue RNA - small intestine [nTPM]":"16.1","Tissue RNA - smooth muscle [nTPM]":"13.0","Tissue RNA - spinal cord [nTPM]":"19.7","Tissue RNA - spleen [nTPM]":"7.7","Tissue RNA - stomach 1 [nTPM]":"27.4","Tissue RNA - testis [nTPM]":"10.3","Tissue RNA - thalamus [nTPM]":"20.5","Tissue RNA - thymus [nTPM]":"4.4","Tissue RNA - thyroid gland [nTPM]":"23.2","Tissue RNA - tongue [nTPM]":"10.9","Tissue RNA - tonsil [nTPM]":"12.4","Tissue RNA - urinary bladder [nTPM]":"21.7","Tissue RNA - vagina [nTPM]":"19.2","Tissue RNA - white matter [nTPM]":"21.6","Cell RNA - A-431 [nTPM]":"24.5","Cell RNA - A549 [nTPM]":"24.2","Cell RNA - AF22 [nTPM]":"33.4","Cell RNA - AN3-CA [nTPM]":"12.9","Cell RNA - ASC diff [nTPM]":"23.9","Cell RNA - ASC TERT1 [nTPM]":"26.8","Cell RNA - BEWO [nTPM]":"35.4","Cell RNA - BJ [nTPM]":"78.3","Cell RNA - BJ hTERT+ [nTPM]":"38.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"45.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"48.5","Cell RNA - CACO-2 [nTPM]":"57.0","Cell RNA - CAPAN-2 [nTPM]":"26.1","Cell RNA - Daudi [nTPM]":"28.5","Cell RNA - EFO-21 [nTPM]":"53.5","Cell RNA - fHDF\/TERT166 [nTPM]":"51.6","Cell RNA - GAMG [nTPM]":"60.8","Cell RNA - HaCaT [nTPM]":"38.0","Cell RNA - HAP1 [nTPM]":"47.5","Cell RNA - HBEC3-KT [nTPM]":"54.8","Cell RNA - HBF TERT88 [nTPM]":"50.6","Cell RNA - HDLM-2 [nTPM]":"19.7","Cell RNA - HEK 293 [nTPM]":"28.8","Cell RNA - HEL [nTPM]":"7.5","Cell RNA - HeLa [nTPM]":"44.6","Cell RNA - Hep G2 [nTPM]":"55.8","Cell RNA - HHSteC [nTPM]":"70.9","Cell RNA - HL-60 [nTPM]":"18.4","Cell RNA - HMC-1 [nTPM]":"4.0","Cell RNA - HSkMC [nTPM]":"47.8","Cell RNA - hTCEpi [nTPM]":"77.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"43.9","Cell RNA - hTERT-HME1 [nTPM]":"53.0","Cell RNA - hTERT-RPE1 [nTPM]":"36.5","Cell RNA - HUVEC TERT2 [nTPM]":"35.2","Cell RNA - JURKAT [nTPM]":"24.6","Cell RNA - K-562 [nTPM]":"24.9","Cell RNA - Karpas-707 [nTPM]":"16.8","Cell RNA - LHCN-M2 [nTPM]":"30.1","Cell RNA - MCF7 [nTPM]":"29.8","Cell RNA - MOLT-4 [nTPM]":"14.8","Cell RNA - NB-4 [nTPM]":"23.8","Cell RNA - NTERA-2 [nTPM]":"23.1","Cell RNA - OE19 [nTPM]":"54.2","Cell RNA - PC-3 [nTPM]":"48.3","Cell RNA - REH [nTPM]":"9.4","Cell RNA - RH-30 [nTPM]":"6.3","Cell RNA - RPMI-8226 [nTPM]":"37.6","Cell RNA - RPTEC TERT1 [nTPM]":"101.2","Cell RNA - RT4 [nTPM]":"38.8","Cell RNA - SCLC-21H [nTPM]":"32.2","Cell RNA - SH-SY5Y [nTPM]":"32.5","Cell RNA - SiHa [nTPM]":"41.1","Cell RNA - SK-BR-3 [nTPM]":"43.8","Cell RNA - SK-MEL-30 [nTPM]":"26.0","Cell RNA - SuSa [nTPM]":"109.0","Cell RNA - T-47d [nTPM]":"32.3","Cell RNA - THP-1 [nTPM]":"15.2","Cell RNA - TIME [nTPM]":"40.2","Cell RNA - U-138 MG [nTPM]":"42.5","Cell RNA - U-2 OS [nTPM]":"43.0","Cell RNA - U-2197 [nTPM]":"49.7","Cell RNA - U-251 MG [nTPM]":"60.7","Cell RNA - U-266\/70 [nTPM]":"9.9","Cell RNA - U-266\/84 [nTPM]":"20.8","Cell RNA - U-698 [nTPM]":"69.4","Cell RNA - U-87 MG [nTPM]":"29.3","Cell RNA - U-937 [nTPM]":"19.4","Cell RNA - WM-115 [nTPM]":"44.1","Blood RNA - basophil [nTPM]":"1.1","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"1.2","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"1.3","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.7","Blood RNA - memory CD8 T-cell [nTPM]":"1.8","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"1.6","Blood RNA - naive CD4 T-cell [nTPM]":"1.1","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"2.0","Blood RNA - plasmacytoid DC [nTPM]":"2.0","Blood RNA - T-reg [nTPM]":"1.9","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"17.6","Brain RNA - basal ganglia [nTPM]":"18.7","Brain RNA - cerebellum [nTPM]":"20.2","Brain RNA - cerebral cortex [nTPM]":"27.6","Brain RNA - hippocampal formation [nTPM]":"16.5","Brain RNA - hypothalamus [nTPM]":"25.1","Brain RNA - medulla oblongata [nTPM]":"23.1","Brain RNA - midbrain [nTPM]":"26.1","Brain RNA - pons [nTPM]":"24.6","Brain RNA - spinal cord [nTPM]":"19.7","Brain RNA - thalamus [nTPM]":"20.5","Brain RNA - white matter [nTPM]":"21.6","Single Cell Type RNA - Adipocytes [nTPM]":"43.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.5","Single Cell Type RNA - Astrocytes [nTPM]":"13.1","Single Cell Type RNA - B-cells [nTPM]":"28.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"122.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"80.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"146.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"59.2","Single Cell Type RNA - Bipolar cells [nTPM]":"17.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"69.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"69.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"95.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"47.1","Single Cell Type RNA - Club cells [nTPM]":"85.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"55.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"56.7","Single Cell Type RNA - dendritic cells [nTPM]":"41.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"80.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"211.3","Single Cell Type RNA - Ductal cells [nTPM]":"91.9","Single Cell Type RNA - Early spermatids [nTPM]":"5.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"66.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"37.0","Single Cell Type RNA - Endothelial cells [nTPM]":"42.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"80.0","Single Cell Type RNA - Erythroid cells [nTPM]":"23.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"78.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"120.7","Single Cell Type RNA - Fibroblasts [nTPM]":"47.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"37.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"72.6","Single Cell Type RNA - granulocytes [nTPM]":"20.8","Single Cell Type RNA - Granulosa cells [nTPM]":"45.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"34.6","Single Cell Type RNA - Hepatocytes [nTPM]":"123.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"36.9","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"73.1","Single Cell Type RNA - Ionocytes [nTPM]":"150.5","Single Cell Type RNA - Kupffer cells [nTPM]":"21.4","Single Cell Type RNA - Langerhans cells [nTPM]":"38.1","Single Cell Type RNA - Late spermatids [nTPM]":"7.6","Single Cell Type RNA - Leydig cells [nTPM]":"14.6","Single Cell Type RNA - Macrophages [nTPM]":"28.4","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"26.1","Single Cell Type RNA - Muller glia cells [nTPM]":"48.5","Single Cell Type RNA - NK-cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"36.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"114.4","Single Cell Type RNA - Paneth cells [nTPM]":"74.4","Single Cell Type RNA - Peritubular cells [nTPM]":"25.9","Single Cell Type RNA - Plasma cells [nTPM]":"33.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"91.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"58.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"151.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"80.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.3","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"70.8","Single Cell Type RNA - Spermatocytes [nTPM]":"23.3","Single Cell Type RNA - Spermatogonia [nTPM]":"92.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"65.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"131.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"70.3","Single Cell Type RNA - T-cells [nTPM]":"28.5","Single Cell Type RNA - Theca cells [nTPM]":"59.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"44.4","Single Cell Type RNA - Urothelial cells [nTPM]":"114.9"},{"Gene":"PUS1","Gene synonym":[],"Ensembl":"ENSG00000177192","Gene description":"Pseudouridine synthase 1","Uniprot":["Q9Y606"],"Chromosome":"12","Position":"131929200-131945896","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["tRNA processing"],"Molecular function":["Isomerase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051636","HPA057593"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA051636":"AB_2681560","HPA057593":"AB_2683479"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.49e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Tissue RNA - adipose tissue [nTPM]":"12.5","Tissue RNA - adrenal gland [nTPM]":"14.9","Tissue RNA - amygdala [nTPM]":"10.1","Tissue RNA - appendix [nTPM]":"14.9","Tissue RNA - basal ganglia [nTPM]":"8.4","Tissue RNA - bone marrow [nTPM]":"23.0","Tissue RNA - breast [nTPM]":"10.4","Tissue RNA - cerebellum [nTPM]":"8.2","Tissue RNA - cerebral cortex [nTPM]":"10.2","Tissue RNA - cervix [nTPM]":"9.7","Tissue RNA - choroid plexus [nTPM]":"7.6","Tissue RNA - colon [nTPM]":"11.9","Tissue RNA - duodenum [nTPM]":"9.7","Tissue RNA - endometrium 1 [nTPM]":"12.5","Tissue RNA - epididymis [nTPM]":"14.0","Tissue RNA - esophagus [nTPM]":"16.5","Tissue RNA - fallopian tube [nTPM]":"11.2","Tissue RNA - gallbladder [nTPM]":"7.1","Tissue RNA - heart muscle [nTPM]":"8.7","Tissue RNA - hippocampal formation [nTPM]":"8.9","Tissue RNA - hypothalamus [nTPM]":"5.9","Tissue RNA - kidney [nTPM]":"13.0","Tissue RNA - liver [nTPM]":"21.6","Tissue RNA - lung [nTPM]":"9.0","Tissue RNA - lymph node [nTPM]":"18.5","Tissue RNA - medulla oblongata [nTPM]":"7.1","Tissue RNA - midbrain [nTPM]":"5.1","Tissue RNA - ovary [nTPM]":"8.6","Tissue RNA - pancreas [nTPM]":"14.8","Tissue RNA - parathyroid gland [nTPM]":"5.4","Tissue RNA - pituitary gland [nTPM]":"8.7","Tissue RNA - placenta [nTPM]":"6.4","Tissue RNA - pons [nTPM]":"6.2","Tissue RNA - prostate [nTPM]":"10.9","Tissue RNA - rectum [nTPM]":"7.9","Tissue RNA - retina [nTPM]":"5.0","Tissue RNA - salivary gland [nTPM]":"9.3","Tissue RNA - seminal vesicle [nTPM]":"6.8","Tissue RNA - skeletal muscle [nTPM]":"14.2","Tissue RNA - skin 1 [nTPM]":"14.4","Tissue RNA - small intestine [nTPM]":"14.0","Tissue RNA - smooth muscle [nTPM]":"7.4","Tissue RNA - spinal cord [nTPM]":"4.4","Tissue RNA - spleen [nTPM]":"15.8","Tissue RNA - stomach 1 [nTPM]":"12.7","Tissue RNA - testis [nTPM]":"13.0","Tissue RNA - thalamus [nTPM]":"6.9","Tissue RNA - thymus [nTPM]":"8.6","Tissue RNA - thyroid gland [nTPM]":"9.5","Tissue RNA - tongue [nTPM]":"4.8","Tissue RNA - tonsil [nTPM]":"10.6","Tissue RNA - urinary bladder [nTPM]":"14.2","Tissue RNA - vagina [nTPM]":"10.7","Tissue RNA - white matter [nTPM]":"9.2","Cell RNA - A-431 [nTPM]":"45.3","Cell RNA - A549 [nTPM]":"58.1","Cell RNA - AF22 [nTPM]":"13.7","Cell RNA - AN3-CA [nTPM]":"24.0","Cell RNA - ASC diff [nTPM]":"13.0","Cell RNA - ASC TERT1 [nTPM]":"21.5","Cell RNA - BEWO [nTPM]":"82.2","Cell RNA - BJ [nTPM]":"34.5","Cell RNA - BJ hTERT+ [nTPM]":"14.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"25.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.3","Cell RNA - CACO-2 [nTPM]":"64.5","Cell RNA - CAPAN-2 [nTPM]":"28.7","Cell RNA - Daudi [nTPM]":"53.2","Cell RNA - EFO-21 [nTPM]":"38.3","Cell RNA - fHDF\/TERT166 [nTPM]":"18.6","Cell RNA - GAMG [nTPM]":"19.9","Cell RNA - HaCaT [nTPM]":"56.0","Cell RNA - HAP1 [nTPM]":"44.4","Cell RNA - HBEC3-KT [nTPM]":"32.2","Cell RNA - HBF TERT88 [nTPM]":"16.3","Cell RNA - HDLM-2 [nTPM]":"24.0","Cell RNA - HEK 293 [nTPM]":"90.6","Cell RNA - HEL [nTPM]":"54.0","Cell RNA - HeLa [nTPM]":"30.9","Cell RNA - Hep G2 [nTPM]":"56.9","Cell RNA - HHSteC [nTPM]":"34.0","Cell RNA - HL-60 [nTPM]":"93.5","Cell RNA - HMC-1 [nTPM]":"47.4","Cell RNA - HSkMC [nTPM]":"21.7","Cell RNA - hTCEpi [nTPM]":"25.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"28.9","Cell RNA - hTERT-HME1 [nTPM]":"24.8","Cell RNA - hTERT-RPE1 [nTPM]":"12.3","Cell RNA - HUVEC TERT2 [nTPM]":"25.0","Cell RNA - JURKAT [nTPM]":"36.8","Cell RNA - K-562 [nTPM]":"68.0","Cell RNA - Karpas-707 [nTPM]":"15.6","Cell RNA - LHCN-M2 [nTPM]":"14.9","Cell RNA - MCF7 [nTPM]":"77.9","Cell RNA - MOLT-4 [nTPM]":"61.9","Cell RNA - NB-4 [nTPM]":"83.4","Cell RNA - NTERA-2 [nTPM]":"71.5","Cell RNA - OE19 [nTPM]":"36.7","Cell RNA - PC-3 [nTPM]":"87.3","Cell RNA - REH [nTPM]":"57.8","Cell RNA - RH-30 [nTPM]":"19.2","Cell RNA - RPMI-8226 [nTPM]":"55.4","Cell RNA - RPTEC TERT1 [nTPM]":"20.8","Cell RNA - RT4 [nTPM]":"61.7","Cell RNA - SCLC-21H [nTPM]":"37.5","Cell RNA - SH-SY5Y [nTPM]":"20.8","Cell RNA - SiHa [nTPM]":"28.6","Cell RNA - SK-BR-3 [nTPM]":"38.9","Cell RNA - SK-MEL-30 [nTPM]":"32.5","Cell RNA - SuSa [nTPM]":"13.1","Cell RNA - T-47d [nTPM]":"42.5","Cell RNA - THP-1 [nTPM]":"99.3","Cell RNA - TIME [nTPM]":"22.7","Cell RNA - U-138 MG [nTPM]":"20.2","Cell RNA - U-2 OS [nTPM]":"43.3","Cell RNA - U-2197 [nTPM]":"43.1","Cell RNA - U-251 MG [nTPM]":"50.0","Cell RNA - U-266\/70 [nTPM]":"43.5","Cell RNA - U-266\/84 [nTPM]":"35.5","Cell RNA - U-698 [nTPM]":"64.5","Cell RNA - U-87 MG [nTPM]":"20.7","Cell RNA - U-937 [nTPM]":"73.6","Cell RNA - WM-115 [nTPM]":"28.4","Blood RNA - basophil [nTPM]":"1.0","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"2.0","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"1.5","Blood RNA - memory B-cell [nTPM]":"4.6","Blood RNA - memory CD4 T-cell [nTPM]":"1.7","Blood RNA - memory CD8 T-cell [nTPM]":"2.1","Blood RNA - myeloid DC [nTPM]":"1.1","Blood RNA - naive B-cell [nTPM]":"4.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.4","Blood RNA - naive CD8 T-cell [nTPM]":"1.3","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"5.6","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"3.0","Blood RNA - T-reg [nTPM]":"1.8","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"10.1","Brain RNA - basal ganglia [nTPM]":"8.4","Brain RNA - cerebellum [nTPM]":"8.2","Brain RNA - cerebral cortex [nTPM]":"10.2","Brain RNA - hippocampal formation [nTPM]":"8.9","Brain RNA - hypothalamus [nTPM]":"5.9","Brain RNA - medulla oblongata [nTPM]":"7.1","Brain RNA - midbrain [nTPM]":"5.1","Brain RNA - pons [nTPM]":"6.2","Brain RNA - spinal cord [nTPM]":"4.4","Brain RNA - thalamus [nTPM]":"6.9","Brain RNA - white matter [nTPM]":"9.2","Single Cell Type RNA - Adipocytes [nTPM]":"7.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.1","Single Cell Type RNA - Astrocytes [nTPM]":"9.8","Single Cell Type RNA - B-cells [nTPM]":"10.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"29.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"6.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"6.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.9","Single Cell Type RNA - dendritic cells [nTPM]":"11.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"12.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.1","Single Cell Type RNA - Endothelial cells [nTPM]":"11.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.4","Single Cell Type RNA - Erythroid cells [nTPM]":"13.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.1","Single Cell Type RNA - Fibroblasts [nTPM]":"8.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.7","Single Cell Type RNA - granulocytes [nTPM]":"16.5","Single Cell Type RNA - Granulosa cells [nTPM]":"11.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"12.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.1","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"7.3","Single Cell Type RNA - Langerhans cells [nTPM]":"8.1","Single Cell Type RNA - Late spermatids [nTPM]":"3.0","Single Cell Type RNA - Leydig cells [nTPM]":"7.8","Single Cell Type RNA - Macrophages [nTPM]":"7.2","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"8.8","Single Cell Type RNA - Muller glia cells [nTPM]":"4.4","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.3","Single Cell Type RNA - Paneth cells [nTPM]":"6.9","Single Cell Type RNA - Peritubular cells [nTPM]":"9.4","Single Cell Type RNA - Plasma cells [nTPM]":"8.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"35.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.3","Single Cell Type RNA - Spermatocytes [nTPM]":"18.5","Single Cell Type RNA - Spermatogonia [nTPM]":"19.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.6","Single Cell Type RNA - T-cells [nTPM]":"9.5","Single Cell Type RNA - Theca cells [nTPM]":"14.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.8","Single Cell Type RNA - Urothelial cells [nTPM]":"21.4"},{"Gene":"PUS3","Gene synonym":["FKSG32"],"Ensembl":"ENSG00000110060","Gene description":"Pseudouridine synthase 3","Uniprot":["Q9BZE2"],"Chromosome":"11","Position":"125893485-125903221","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["tRNA processing"],"Molecular function":["Isomerase"],"Disease involvement":["Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038040","HPA063802"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA038040":"AB_10697092","HPA063802":"AB_2685126"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.10e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Tissue RNA - adipose tissue [nTPM]":"8.3","Tissue RNA - adrenal gland [nTPM]":"8.4","Tissue RNA - amygdala [nTPM]":"7.1","Tissue RNA - appendix [nTPM]":"8.2","Tissue RNA - basal ganglia [nTPM]":"7.8","Tissue RNA - bone marrow [nTPM]":"3.3","Tissue RNA - breast [nTPM]":"9.4","Tissue RNA - cerebellum [nTPM]":"8.4","Tissue RNA - cerebral cortex [nTPM]":"11.6","Tissue RNA - cervix [nTPM]":"7.7","Tissue RNA - choroid plexus [nTPM]":"6.7","Tissue RNA - colon [nTPM]":"8.5","Tissue RNA - duodenum [nTPM]":"10.9","Tissue RNA - endometrium 1 [nTPM]":"7.8","Tissue RNA - epididymis [nTPM]":"9.7","Tissue RNA - esophagus [nTPM]":"9.0","Tissue RNA - fallopian tube [nTPM]":"7.4","Tissue RNA - gallbladder [nTPM]":"6.5","Tissue RNA - heart muscle [nTPM]":"7.1","Tissue RNA - hippocampal formation [nTPM]":"7.1","Tissue RNA - hypothalamus [nTPM]":"8.7","Tissue RNA - kidney [nTPM]":"9.0","Tissue RNA - liver [nTPM]":"33.2","Tissue RNA - lung [nTPM]":"6.1","Tissue RNA - lymph node [nTPM]":"9.2","Tissue RNA - medulla oblongata [nTPM]":"7.8","Tissue RNA - midbrain [nTPM]":"7.8","Tissue RNA - ovary [nTPM]":"7.3","Tissue RNA - pancreas [nTPM]":"17.8","Tissue RNA - parathyroid gland [nTPM]":"7.0","Tissue RNA - pituitary gland [nTPM]":"8.5","Tissue RNA - placenta [nTPM]":"6.7","Tissue RNA - pons [nTPM]":"7.3","Tissue RNA - prostate [nTPM]":"8.7","Tissue RNA - rectum [nTPM]":"7.9","Tissue RNA - retina [nTPM]":"8.4","Tissue RNA - salivary gland [nTPM]":"7.7","Tissue RNA - seminal vesicle [nTPM]":"5.4","Tissue RNA - skeletal muscle [nTPM]":"15.0","Tissue RNA - skin 1 [nTPM]":"9.5","Tissue RNA - small intestine [nTPM]":"6.8","Tissue RNA - smooth muscle [nTPM]":"9.7","Tissue RNA - spinal cord [nTPM]":"7.0","Tissue RNA - spleen [nTPM]":"7.6","Tissue RNA - stomach 1 [nTPM]":"10.1","Tissue RNA - testis [nTPM]":"7.2","Tissue RNA - thalamus [nTPM]":"8.5","Tissue RNA - thymus [nTPM]":"11.0","Tissue RNA - thyroid gland [nTPM]":"9.3","Tissue RNA - tongue [nTPM]":"15.2","Tissue RNA - tonsil [nTPM]":"10.5","Tissue RNA - urinary bladder [nTPM]":"10.1","Tissue RNA - vagina [nTPM]":"6.3","Tissue RNA - white matter [nTPM]":"7.6","Cell RNA - A-431 [nTPM]":"6.5","Cell RNA - A549 [nTPM]":"7.9","Cell RNA - AF22 [nTPM]":"23.2","Cell RNA - AN3-CA [nTPM]":"24.9","Cell RNA - ASC diff [nTPM]":"24.3","Cell RNA - ASC TERT1 [nTPM]":"29.7","Cell RNA - BEWO [nTPM]":"11.0","Cell RNA - BJ [nTPM]":"21.1","Cell RNA - BJ hTERT+ [nTPM]":"17.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.2","Cell RNA - CACO-2 [nTPM]":"24.0","Cell RNA - CAPAN-2 [nTPM]":"23.2","Cell RNA - Daudi [nTPM]":"31.4","Cell RNA - EFO-21 [nTPM]":"33.3","Cell RNA - fHDF\/TERT166 [nTPM]":"9.2","Cell RNA - GAMG [nTPM]":"17.1","Cell RNA - HaCaT [nTPM]":"22.5","Cell RNA - HAP1 [nTPM]":"37.6","Cell RNA - HBEC3-KT [nTPM]":"19.7","Cell RNA - HBF TERT88 [nTPM]":"11.5","Cell RNA - HDLM-2 [nTPM]":"28.2","Cell RNA - HEK 293 [nTPM]":"18.2","Cell RNA - HEL [nTPM]":"31.2","Cell RNA - HeLa [nTPM]":"9.5","Cell RNA - Hep G2 [nTPM]":"18.6","Cell RNA - HHSteC [nTPM]":"24.6","Cell RNA - HL-60 [nTPM]":"20.5","Cell RNA - HMC-1 [nTPM]":"9.2","Cell RNA - HSkMC [nTPM]":"23.1","Cell RNA - hTCEpi [nTPM]":"23.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.7","Cell RNA - hTERT-HME1 [nTPM]":"29.8","Cell RNA - hTERT-RPE1 [nTPM]":"16.2","Cell RNA - HUVEC TERT2 [nTPM]":"21.0","Cell RNA - JURKAT [nTPM]":"23.5","Cell RNA - K-562 [nTPM]":"34.0","Cell RNA - Karpas-707 [nTPM]":"16.1","Cell RNA - LHCN-M2 [nTPM]":"13.0","Cell RNA - MCF7 [nTPM]":"4.0","Cell RNA - MOLT-4 [nTPM]":"23.7","Cell RNA - NB-4 [nTPM]":"23.6","Cell RNA - NTERA-2 [nTPM]":"19.8","Cell RNA - OE19 [nTPM]":"47.0","Cell RNA - PC-3 [nTPM]":"15.8","Cell RNA - REH [nTPM]":"4.8","Cell RNA - RH-30 [nTPM]":"20.5","Cell RNA - RPMI-8226 [nTPM]":"18.4","Cell RNA - RPTEC TERT1 [nTPM]":"20.3","Cell RNA - RT4 [nTPM]":"9.5","Cell RNA - SCLC-21H [nTPM]":"27.1","Cell RNA - SH-SY5Y [nTPM]":"25.7","Cell RNA - SiHa [nTPM]":"13.1","Cell RNA - SK-BR-3 [nTPM]":"21.4","Cell RNA - SK-MEL-30 [nTPM]":"11.7","Cell RNA - SuSa [nTPM]":"16.5","Cell RNA - T-47d [nTPM]":"43.2","Cell RNA - THP-1 [nTPM]":"13.8","Cell RNA - TIME [nTPM]":"15.3","Cell RNA - U-138 MG [nTPM]":"24.0","Cell RNA - U-2 OS [nTPM]":"10.1","Cell RNA - U-2197 [nTPM]":"11.9","Cell RNA - U-251 MG [nTPM]":"17.3","Cell RNA - U-266\/70 [nTPM]":"12.4","Cell RNA - U-266\/84 [nTPM]":"20.1","Cell RNA - U-698 [nTPM]":"33.6","Cell RNA - U-87 MG [nTPM]":"6.7","Cell RNA - U-937 [nTPM]":"31.9","Cell RNA - WM-115 [nTPM]":"17.1","Blood RNA - basophil [nTPM]":"14.2","Blood RNA - classical monocyte [nTPM]":"10.5","Blood RNA - eosinophil [nTPM]":"9.9","Blood RNA - gdT-cell [nTPM]":"13.4","Blood RNA - intermediate monocyte [nTPM]":"10.8","Blood RNA - MAIT T-cell [nTPM]":"15.3","Blood RNA - memory B-cell [nTPM]":"13.3","Blood RNA - memory CD4 T-cell [nTPM]":"13.1","Blood RNA - memory CD8 T-cell [nTPM]":"12.8","Blood RNA - myeloid DC [nTPM]":"9.2","Blood RNA - naive B-cell [nTPM]":"14.8","Blood RNA - naive CD4 T-cell [nTPM]":"17.0","Blood RNA - naive CD8 T-cell [nTPM]":"16.0","Blood RNA - neutrophil [nTPM]":"4.2","Blood RNA - NK-cell [nTPM]":"14.9","Blood RNA - non-classical monocyte [nTPM]":"14.0","Blood RNA - plasmacytoid DC [nTPM]":"8.0","Blood RNA - T-reg [nTPM]":"15.0","Blood RNA - total PBMC [nTPM]":"8.3","Brain RNA - amygdala [nTPM]":"7.1","Brain RNA - basal ganglia [nTPM]":"7.8","Brain RNA - cerebellum [nTPM]":"8.4","Brain RNA - cerebral cortex [nTPM]":"11.6","Brain RNA - hippocampal formation [nTPM]":"7.1","Brain RNA - hypothalamus [nTPM]":"8.7","Brain RNA - medulla oblongata [nTPM]":"7.8","Brain RNA - midbrain [nTPM]":"7.8","Brain RNA - pons [nTPM]":"7.3","Brain RNA - spinal cord [nTPM]":"7.0","Brain RNA - thalamus [nTPM]":"8.5","Brain RNA - white matter [nTPM]":"7.6","Single Cell Type RNA - Adipocytes [nTPM]":"8.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.5","Single Cell Type RNA - Astrocytes [nTPM]":"3.6","Single Cell Type RNA - B-cells [nTPM]":"9.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"9.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"13.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.7","Single Cell Type RNA - dendritic cells [nTPM]":"7.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"17.8","Single Cell Type RNA - Early spermatids [nTPM]":"7.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.9","Single Cell Type RNA - Endothelial cells [nTPM]":"10.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"14.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"27.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.7","Single Cell Type RNA - Fibroblasts [nTPM]":"6.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.4","Single Cell Type RNA - granulocytes [nTPM]":"12.7","Single Cell Type RNA - Granulosa cells [nTPM]":"6.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.4","Single Cell Type RNA - Hepatocytes [nTPM]":"33.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.2","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.6","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.0","Single Cell Type RNA - Langerhans cells [nTPM]":"2.9","Single Cell Type RNA - Late spermatids [nTPM]":"6.3","Single Cell Type RNA - Leydig cells [nTPM]":"7.8","Single Cell Type RNA - Macrophages [nTPM]":"5.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"9.9","Single Cell Type RNA - Muller glia cells [nTPM]":"9.8","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.0","Single Cell Type RNA - Paneth cells [nTPM]":"3.9","Single Cell Type RNA - Peritubular cells [nTPM]":"7.9","Single Cell Type RNA - Plasma cells [nTPM]":"6.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.1","Single Cell Type RNA - Spermatocytes [nTPM]":"7.8","Single Cell Type RNA - Spermatogonia [nTPM]":"7.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.0","Single Cell Type RNA - T-cells [nTPM]":"7.9","Single Cell Type RNA - Theca cells [nTPM]":"12.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.5","Single Cell Type RNA - Urothelial cells [nTPM]":"10.9"},{"Gene":"PXDN","Gene synonym":["D2S448","D2S448E","KIAA0230","MG50","PRG2","PXN"],"Ensembl":"ENSG00000130508","Gene description":"Peroxidasin","Uniprot":["Q92626"],"Chromosome":"2","Position":"1631887-1744852","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Hydrogen peroxide"],"Molecular function":["Oxidoreductase","Peroxidase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"79.1","Endometrial stromal cells":"99.4","Endothelial cells":"95.1","Hepatic stellate cells":"71.4","Skeletal myocytes":"120.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"323.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012375"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9100000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA012375":"AB_1855965"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.28e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.75e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.73e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.33e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-3"},"Tissue RNA - adipose tissue [nTPM]":"59.5","Tissue RNA - adrenal gland [nTPM]":"5.5","Tissue RNA - amygdala [nTPM]":"4.1","Tissue RNA - appendix [nTPM]":"24.3","Tissue RNA - basal ganglia [nTPM]":"3.5","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"33.7","Tissue RNA - cerebellum [nTPM]":"1.9","Tissue RNA - cerebral cortex [nTPM]":"4.1","Tissue RNA - cervix [nTPM]":"18.2","Tissue RNA - choroid plexus [nTPM]":"27.5","Tissue RNA - colon [nTPM]":"36.1","Tissue RNA - duodenum [nTPM]":"7.9","Tissue RNA - endometrium 1 [nTPM]":"32.8","Tissue RNA - epididymis [nTPM]":"4.0","Tissue RNA - esophagus [nTPM]":"4.9","Tissue RNA - fallopian tube [nTPM]":"18.0","Tissue RNA - gallbladder [nTPM]":"22.7","Tissue RNA - heart muscle [nTPM]":"22.7","Tissue RNA - hippocampal formation [nTPM]":"3.1","Tissue RNA - hypothalamus [nTPM]":"7.7","Tissue RNA - kidney [nTPM]":"9.0","Tissue RNA - liver [nTPM]":"12.4","Tissue RNA - lung [nTPM]":"27.6","Tissue RNA - lymph node [nTPM]":"5.0","Tissue RNA - medulla oblongata [nTPM]":"4.2","Tissue RNA - midbrain [nTPM]":"6.2","Tissue RNA - ovary [nTPM]":"32.7","Tissue RNA - pancreas [nTPM]":"3.8","Tissue RNA - parathyroid gland [nTPM]":"3.0","Tissue RNA - pituitary gland [nTPM]":"11.7","Tissue RNA - placenta [nTPM]":"33.4","Tissue RNA - pons [nTPM]":"4.7","Tissue RNA - prostate [nTPM]":"17.5","Tissue RNA - rectum [nTPM]":"8.7","Tissue RNA - retina [nTPM]":"5.2","Tissue RNA - salivary gland [nTPM]":"13.6","Tissue RNA - seminal vesicle [nTPM]":"11.1","Tissue RNA - skeletal muscle [nTPM]":"7.7","Tissue RNA - skin 1 [nTPM]":"6.9","Tissue RNA - small intestine [nTPM]":"16.3","Tissue RNA - smooth muscle [nTPM]":"61.8","Tissue RNA - spinal cord [nTPM]":"2.6","Tissue RNA - spleen [nTPM]":"10.0","Tissue RNA - stomach 1 [nTPM]":"13.2","Tissue RNA - testis [nTPM]":"6.4","Tissue RNA - thalamus [nTPM]":"5.2","Tissue RNA - thymus [nTPM]":"2.1","Tissue RNA - thyroid gland [nTPM]":"8.4","Tissue RNA - tongue [nTPM]":"11.5","Tissue RNA - tonsil [nTPM]":"2.1","Tissue RNA - urinary bladder [nTPM]":"33.8","Tissue RNA - vagina [nTPM]":"13.5","Tissue RNA - white matter [nTPM]":"3.4","Cell RNA - A-431 [nTPM]":"39.9","Cell RNA - A549 [nTPM]":"13.9","Cell RNA - AF22 [nTPM]":"72.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"198.3","Cell RNA - ASC TERT1 [nTPM]":"180.9","Cell RNA - BEWO [nTPM]":"54.6","Cell RNA - BJ [nTPM]":"231.4","Cell RNA - BJ hTERT+ [nTPM]":"182.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"99.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"107.9","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.5","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"323.8","Cell RNA - fHDF\/TERT166 [nTPM]":"230.3","Cell RNA - GAMG [nTPM]":"4.5","Cell RNA - HaCaT [nTPM]":"8.3","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"142.3","Cell RNA - HBF TERT88 [nTPM]":"125.5","Cell RNA - HDLM-2 [nTPM]":"0.6","Cell RNA - HEK 293 [nTPM]":"2.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"139.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"196.4","Cell RNA - HL-60 [nTPM]":"0.6","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"200.7","Cell RNA - hTCEpi [nTPM]":"41.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"112.2","Cell RNA - hTERT-HME1 [nTPM]":"83.8","Cell RNA - hTERT-RPE1 [nTPM]":"299.5","Cell RNA - HUVEC TERT2 [nTPM]":"247.0","Cell RNA - JURKAT [nTPM]":"35.9","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"142.6","Cell RNA - MCF7 [nTPM]":"23.6","Cell RNA - MOLT-4 [nTPM]":"6.8","Cell RNA - NB-4 [nTPM]":"8.0","Cell RNA - NTERA-2 [nTPM]":"58.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"52.3","Cell RNA - REH [nTPM]":"13.2","Cell RNA - RH-30 [nTPM]":"250.8","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"115.9","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"131.9","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"73.6","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"142.9","Cell RNA - T-47d [nTPM]":"27.0","Cell RNA - THP-1 [nTPM]":"0.9","Cell RNA - TIME [nTPM]":"242.4","Cell RNA - U-138 MG [nTPM]":"162.8","Cell RNA - U-2 OS [nTPM]":"79.7","Cell RNA - U-2197 [nTPM]":"6.2","Cell RNA - U-251 MG [nTPM]":"180.7","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"205.4","Cell RNA - U-698 [nTPM]":"1.0","Cell RNA - U-87 MG [nTPM]":"0.8","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.1","Brain RNA - basal ganglia [nTPM]":"3.5","Brain RNA - cerebellum [nTPM]":"1.9","Brain RNA - cerebral cortex [nTPM]":"4.1","Brain RNA - hippocampal formation [nTPM]":"3.1","Brain RNA - hypothalamus [nTPM]":"7.7","Brain RNA - medulla oblongata [nTPM]":"4.2","Brain RNA - midbrain [nTPM]":"6.2","Brain RNA - pons [nTPM]":"4.7","Brain RNA - spinal cord [nTPM]":"2.6","Brain RNA - thalamus [nTPM]":"5.2","Brain RNA - white matter [nTPM]":"3.4","Single Cell Type RNA - Adipocytes [nTPM]":"79.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.3","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"2.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"7.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"10.4","Single Cell Type RNA - Early spermatids [nTPM]":"33.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"99.4","Single Cell Type RNA - Endothelial cells [nTPM]":"95.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.3","Single Cell Type RNA - Fibroblasts [nTPM]":"45.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.4","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"43.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"71.4","Single Cell Type RNA - Hepatocytes [nTPM]":"1.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.3","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"5.7","Single Cell Type RNA - Langerhans cells [nTPM]":"4.4","Single Cell Type RNA - Late spermatids [nTPM]":"40.7","Single Cell Type RNA - Leydig cells [nTPM]":"26.8","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"10.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"55.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"15.1","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"120.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"51.1","Single Cell Type RNA - Spermatocytes [nTPM]":"22.0","Single Cell Type RNA - Spermatogonia [nTPM]":"16.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"33.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.5","Single Cell Type RNA - Urothelial cells [nTPM]":"1.4"},{"Gene":"PYCR1","Gene synonym":["P5C"],"Ensembl":"ENSG00000183010","Gene description":"Pyrroline-5-carboxylate reductase 1","Uniprot":["P32322"],"Chromosome":"17","Position":"81932384-81942412","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Amino-acid biosynthesis","Proline biosynthesis","Stress response"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"111.8","salivary gland":"121.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Exocrine glandular cells":"63.8","Extravillous trophoblasts":"63.8","Intestinal goblet cells":"83.4","Prostatic glandular cells":"59.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"4.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"B-cells":"4.2","dendritic cells":"1.9","T-cells":"1.6"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047660"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 30: Mammary glandular cells - Lactation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047660":"AB_2680115"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.86e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.33e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.33e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.5","Tissue RNA - adrenal gland [nTPM]":"4.1","Tissue RNA - amygdala [nTPM]":"13.8","Tissue RNA - appendix [nTPM]":"13.8","Tissue RNA - basal ganglia [nTPM]":"14.1","Tissue RNA - bone marrow [nTPM]":"12.5","Tissue RNA - breast [nTPM]":"17.4","Tissue RNA - cerebellum [nTPM]":"13.2","Tissue RNA - cerebral cortex [nTPM]":"15.2","Tissue RNA - cervix [nTPM]":"24.2","Tissue RNA - choroid plexus [nTPM]":"9.6","Tissue RNA - colon [nTPM]":"23.8","Tissue RNA - duodenum [nTPM]":"14.3","Tissue RNA - endometrium 1 [nTPM]":"10.6","Tissue RNA - epididymis [nTPM]":"2.5","Tissue RNA - esophagus [nTPM]":"18.7","Tissue RNA - fallopian tube [nTPM]":"9.7","Tissue RNA - gallbladder [nTPM]":"8.9","Tissue RNA - heart muscle [nTPM]":"10.0","Tissue RNA - hippocampal formation [nTPM]":"12.5","Tissue RNA - hypothalamus [nTPM]":"14.4","Tissue RNA - kidney [nTPM]":"6.3","Tissue RNA - liver [nTPM]":"8.7","Tissue RNA - lung [nTPM]":"13.6","Tissue RNA - lymph node [nTPM]":"6.9","Tissue RNA - medulla oblongata [nTPM]":"16.1","Tissue RNA - midbrain [nTPM]":"13.9","Tissue RNA - ovary [nTPM]":"7.5","Tissue RNA - pancreas [nTPM]":"111.8","Tissue RNA - parathyroid gland [nTPM]":"1.9","Tissue RNA - pituitary gland [nTPM]":"21.6","Tissue RNA - placenta [nTPM]":"11.7","Tissue RNA - pons [nTPM]":"14.8","Tissue RNA - prostate [nTPM]":"25.5","Tissue RNA - rectum [nTPM]":"14.4","Tissue RNA - retina [nTPM]":"0.9","Tissue RNA - salivary gland [nTPM]":"121.1","Tissue RNA - seminal vesicle [nTPM]":"7.8","Tissue RNA - skeletal muscle [nTPM]":"11.5","Tissue RNA - skin 1 [nTPM]":"6.3","Tissue RNA - small intestine [nTPM]":"12.5","Tissue RNA - smooth muscle [nTPM]":"12.2","Tissue RNA - spinal cord [nTPM]":"12.7","Tissue RNA - spleen [nTPM]":"8.0","Tissue RNA - stomach 1 [nTPM]":"42.4","Tissue RNA - testis [nTPM]":"15.1","Tissue RNA - thalamus [nTPM]":"15.8","Tissue RNA - thymus [nTPM]":"2.6","Tissue RNA - thyroid gland [nTPM]":"8.5","Tissue RNA - tongue [nTPM]":"2.0","Tissue RNA - tonsil [nTPM]":"6.7","Tissue RNA - urinary bladder [nTPM]":"12.0","Tissue RNA - vagina [nTPM]":"10.3","Tissue RNA - white matter [nTPM]":"14.2","Cell RNA - A-431 [nTPM]":"107.4","Cell RNA - A549 [nTPM]":"111.9","Cell RNA - AF22 [nTPM]":"62.7","Cell RNA - AN3-CA [nTPM]":"228.3","Cell RNA - ASC diff [nTPM]":"36.7","Cell RNA - ASC TERT1 [nTPM]":"69.0","Cell RNA - BEWO [nTPM]":"117.2","Cell RNA - BJ [nTPM]":"176.0","Cell RNA - BJ hTERT+ [nTPM]":"85.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"54.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"73.7","Cell RNA - CACO-2 [nTPM]":"129.3","Cell RNA - CAPAN-2 [nTPM]":"116.9","Cell RNA - Daudi [nTPM]":"163.2","Cell RNA - EFO-21 [nTPM]":"38.0","Cell RNA - fHDF\/TERT166 [nTPM]":"188.9","Cell RNA - GAMG [nTPM]":"33.3","Cell RNA - HaCaT [nTPM]":"45.8","Cell RNA - HAP1 [nTPM]":"148.2","Cell RNA - HBEC3-KT [nTPM]":"67.1","Cell RNA - HBF TERT88 [nTPM]":"32.7","Cell RNA - HDLM-2 [nTPM]":"42.4","Cell RNA - HEK 293 [nTPM]":"18.6","Cell RNA - HEL [nTPM]":"96.5","Cell RNA - HeLa [nTPM]":"56.5","Cell RNA - Hep G2 [nTPM]":"350.8","Cell RNA - HHSteC [nTPM]":"213.8","Cell RNA - HL-60 [nTPM]":"64.8","Cell RNA - HMC-1 [nTPM]":"70.6","Cell RNA - HSkMC [nTPM]":"58.5","Cell RNA - hTCEpi [nTPM]":"129.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"68.2","Cell RNA - hTERT-HME1 [nTPM]":"178.7","Cell RNA - hTERT-RPE1 [nTPM]":"64.8","Cell RNA - HUVEC TERT2 [nTPM]":"95.5","Cell RNA - JURKAT [nTPM]":"129.4","Cell RNA - K-562 [nTPM]":"314.0","Cell RNA - Karpas-707 [nTPM]":"147.2","Cell RNA - LHCN-M2 [nTPM]":"35.1","Cell RNA - MCF7 [nTPM]":"376.4","Cell RNA - MOLT-4 [nTPM]":"68.1","Cell RNA - NB-4 [nTPM]":"49.5","Cell RNA - NTERA-2 [nTPM]":"52.8","Cell RNA - OE19 [nTPM]":"291.9","Cell RNA - PC-3 [nTPM]":"170.1","Cell RNA - REH [nTPM]":"0.9","Cell RNA - RH-30 [nTPM]":"105.6","Cell RNA - RPMI-8226 [nTPM]":"205.5","Cell RNA - RPTEC TERT1 [nTPM]":"49.9","Cell RNA - RT4 [nTPM]":"38.7","Cell RNA - SCLC-21H [nTPM]":"237.7","Cell RNA - SH-SY5Y [nTPM]":"167.2","Cell RNA - SiHa [nTPM]":"36.9","Cell RNA - SK-BR-3 [nTPM]":"203.6","Cell RNA - SK-MEL-30 [nTPM]":"219.5","Cell RNA - SuSa [nTPM]":"46.3","Cell RNA - T-47d [nTPM]":"210.0","Cell RNA - THP-1 [nTPM]":"117.1","Cell RNA - TIME [nTPM]":"70.1","Cell RNA - U-138 MG [nTPM]":"53.7","Cell RNA - U-2 OS [nTPM]":"201.8","Cell RNA - U-2197 [nTPM]":"91.4","Cell RNA - U-251 MG [nTPM]":"66.3","Cell RNA - U-266\/70 [nTPM]":"183.4","Cell RNA - U-266\/84 [nTPM]":"141.3","Cell RNA - U-698 [nTPM]":"156.2","Cell RNA - U-87 MG [nTPM]":"57.2","Cell RNA - U-937 [nTPM]":"0.8","Cell RNA - WM-115 [nTPM]":"178.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"4.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.7","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"1.3","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"1.6","Blood RNA - naive CD8 T-cell [nTPM]":"1.2","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"1.9","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"13.8","Brain RNA - basal ganglia [nTPM]":"14.1","Brain RNA - cerebellum [nTPM]":"13.2","Brain RNA - cerebral cortex [nTPM]":"15.2","Brain RNA - hippocampal formation [nTPM]":"12.5","Brain RNA - hypothalamus [nTPM]":"14.4","Brain RNA - medulla oblongata [nTPM]":"16.1","Brain RNA - midbrain [nTPM]":"13.9","Brain RNA - pons [nTPM]":"14.8","Brain RNA - spinal cord [nTPM]":"12.7","Brain RNA - thalamus [nTPM]":"15.8","Brain RNA - white matter [nTPM]":"14.2","Single Cell Type RNA - Adipocytes [nTPM]":"2.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.9","Single Cell Type RNA - Astrocytes [nTPM]":"2.3","Single Cell Type RNA - B-cells [nTPM]":"9.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"50.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"29.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"7.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.0","Single Cell Type RNA - dendritic cells [nTPM]":"2.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"13.3","Single Cell Type RNA - Early spermatids [nTPM]":"13.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.6","Single Cell Type RNA - Endothelial cells [nTPM]":"4.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.8","Single Cell Type RNA - Erythroid cells [nTPM]":"27.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"63.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"63.8","Single Cell Type RNA - Fibroblasts [nTPM]":"24.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"35.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.8","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"13.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"1.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"83.4","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"5.4","Single Cell Type RNA - Late spermatids [nTPM]":"32.4","Single Cell Type RNA - Leydig cells [nTPM]":"7.5","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"48.0","Single Cell Type RNA - Paneth cells [nTPM]":"19.5","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"34.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"59.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.8","Single Cell Type RNA - Spermatocytes [nTPM]":"28.2","Single Cell Type RNA - Spermatogonia [nTPM]":"16.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.8","Single Cell Type RNA - T-cells [nTPM]":"1.9","Single Cell Type RNA - Theca cells [nTPM]":"15.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"43.1","Single Cell Type RNA - Urothelial cells [nTPM]":"8.6"},{"Gene":"PYCR2","Gene synonym":["P5CR2"],"Ensembl":"ENSG00000143811","Gene description":"Pyrroline-5-carboxylate reductase 2","Uniprot":["Q96C36"],"Chromosome":"1","Position":"225919877-225924340","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Amino-acid biosynthesis","Proline biosynthesis"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Leukodystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056873"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 51: Myeloid cells - Hemostasis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA056873":"AB_2683263"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.02e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.42e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-3"},"Tissue RNA - adipose tissue [nTPM]":"38.0","Tissue RNA - adrenal gland [nTPM]":"71.7","Tissue RNA - amygdala [nTPM]":"53.2","Tissue RNA - appendix [nTPM]":"35.8","Tissue RNA - basal ganglia [nTPM]":"62.4","Tissue RNA - bone marrow [nTPM]":"47.3","Tissue RNA - breast [nTPM]":"35.8","Tissue RNA - cerebellum [nTPM]":"68.1","Tissue RNA - cerebral cortex [nTPM]":"54.2","Tissue RNA - cervix [nTPM]":"46.4","Tissue RNA - choroid plexus [nTPM]":"51.8","Tissue RNA - colon [nTPM]":"39.6","Tissue RNA - duodenum [nTPM]":"22.3","Tissue RNA - endometrium 1 [nTPM]":"48.5","Tissue RNA - epididymis [nTPM]":"26.4","Tissue RNA - esophagus [nTPM]":"32.3","Tissue RNA - fallopian tube [nTPM]":"44.7","Tissue RNA - gallbladder [nTPM]":"22.4","Tissue RNA - heart muscle [nTPM]":"62.3","Tissue RNA - hippocampal formation [nTPM]":"50.4","Tissue RNA - hypothalamus [nTPM]":"61.3","Tissue RNA - kidney [nTPM]":"40.2","Tissue RNA - liver [nTPM]":"40.3","Tissue RNA - lung [nTPM]":"38.2","Tissue RNA - lymph node [nTPM]":"47.2","Tissue RNA - medulla oblongata [nTPM]":"69.0","Tissue RNA - midbrain [nTPM]":"61.2","Tissue RNA - ovary [nTPM]":"47.9","Tissue RNA - pancreas [nTPM]":"47.2","Tissue RNA - parathyroid gland [nTPM]":"42.0","Tissue RNA - pituitary gland [nTPM]":"57.0","Tissue RNA - placenta [nTPM]":"28.5","Tissue RNA - pons [nTPM]":"66.0","Tissue RNA - prostate [nTPM]":"39.6","Tissue RNA - rectum [nTPM]":"18.3","Tissue RNA - retina [nTPM]":"34.0","Tissue RNA - salivary gland [nTPM]":"39.6","Tissue RNA - seminal vesicle [nTPM]":"40.9","Tissue RNA - skeletal muscle [nTPM]":"66.8","Tissue RNA - skin 1 [nTPM]":"28.3","Tissue RNA - small intestine [nTPM]":"34.4","Tissue RNA - smooth muscle [nTPM]":"25.7","Tissue RNA - spinal cord [nTPM]":"68.6","Tissue RNA - spleen [nTPM]":"49.5","Tissue RNA - stomach 1 [nTPM]":"38.9","Tissue RNA - testis [nTPM]":"34.4","Tissue RNA - thalamus [nTPM]":"59.2","Tissue RNA - thymus [nTPM]":"43.9","Tissue RNA - thyroid gland [nTPM]":"30.0","Tissue RNA - tongue [nTPM]":"49.1","Tissue RNA - tonsil [nTPM]":"33.9","Tissue RNA - urinary bladder [nTPM]":"50.3","Tissue RNA - vagina [nTPM]":"33.3","Tissue RNA - white matter [nTPM]":"72.5","Cell RNA - A-431 [nTPM]":"72.6","Cell RNA - A549 [nTPM]":"59.6","Cell RNA - AF22 [nTPM]":"35.0","Cell RNA - AN3-CA [nTPM]":"59.1","Cell RNA - ASC diff [nTPM]":"38.8","Cell RNA - ASC TERT1 [nTPM]":"40.0","Cell RNA - BEWO [nTPM]":"73.2","Cell RNA - BJ [nTPM]":"74.8","Cell RNA - BJ hTERT+ [nTPM]":"46.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"49.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"44.1","Cell RNA - CACO-2 [nTPM]":"77.2","Cell RNA - CAPAN-2 [nTPM]":"58.3","Cell RNA - Daudi [nTPM]":"126.1","Cell RNA - EFO-21 [nTPM]":"156.6","Cell RNA - fHDF\/TERT166 [nTPM]":"55.0","Cell RNA - GAMG [nTPM]":"39.1","Cell RNA - HaCaT [nTPM]":"81.6","Cell RNA - HAP1 [nTPM]":"50.5","Cell RNA - HBEC3-KT [nTPM]":"58.6","Cell RNA - HBF TERT88 [nTPM]":"28.3","Cell RNA - HDLM-2 [nTPM]":"154.6","Cell RNA - HEK 293 [nTPM]":"107.5","Cell RNA - HEL [nTPM]":"120.6","Cell RNA - HeLa [nTPM]":"60.2","Cell RNA - Hep G2 [nTPM]":"81.5","Cell RNA - HHSteC [nTPM]":"59.8","Cell RNA - HL-60 [nTPM]":"107.9","Cell RNA - HMC-1 [nTPM]":"189.1","Cell RNA - HSkMC [nTPM]":"38.8","Cell RNA - hTCEpi [nTPM]":"72.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"56.1","Cell RNA - hTERT-HME1 [nTPM]":"64.1","Cell RNA - hTERT-RPE1 [nTPM]":"44.1","Cell RNA - HUVEC TERT2 [nTPM]":"47.8","Cell RNA - JURKAT [nTPM]":"103.7","Cell RNA - K-562 [nTPM]":"178.4","Cell RNA - Karpas-707 [nTPM]":"81.6","Cell RNA - LHCN-M2 [nTPM]":"50.9","Cell RNA - MCF7 [nTPM]":"60.5","Cell RNA - MOLT-4 [nTPM]":"135.8","Cell RNA - NB-4 [nTPM]":"120.9","Cell RNA - NTERA-2 [nTPM]":"196.0","Cell RNA - OE19 [nTPM]":"112.8","Cell RNA - PC-3 [nTPM]":"80.4","Cell RNA - REH [nTPM]":"120.2","Cell RNA - RH-30 [nTPM]":"79.0","Cell RNA - RPMI-8226 [nTPM]":"263.6","Cell RNA - RPTEC TERT1 [nTPM]":"65.2","Cell RNA - RT4 [nTPM]":"58.3","Cell RNA - SCLC-21H [nTPM]":"44.0","Cell RNA - SH-SY5Y [nTPM]":"56.7","Cell RNA - SiHa [nTPM]":"62.4","Cell RNA - SK-BR-3 [nTPM]":"48.7","Cell RNA - SK-MEL-30 [nTPM]":"161.0","Cell RNA - SuSa [nTPM]":"27.9","Cell RNA - T-47d [nTPM]":"62.3","Cell RNA - THP-1 [nTPM]":"202.0","Cell RNA - TIME [nTPM]":"40.3","Cell RNA - U-138 MG [nTPM]":"38.4","Cell RNA - U-2 OS [nTPM]":"46.5","Cell RNA - U-2197 [nTPM]":"82.9","Cell RNA - U-251 MG [nTPM]":"104.4","Cell RNA - U-266\/70 [nTPM]":"129.9","Cell RNA - U-266\/84 [nTPM]":"156.2","Cell RNA - U-698 [nTPM]":"127.4","Cell RNA - U-87 MG [nTPM]":"60.7","Cell RNA - U-937 [nTPM]":"80.6","Cell RNA - WM-115 [nTPM]":"109.3","Blood RNA - basophil [nTPM]":"38.4","Blood RNA - classical monocyte [nTPM]":"19.6","Blood RNA - eosinophil [nTPM]":"39.6","Blood RNA - gdT-cell [nTPM]":"45.5","Blood RNA - intermediate monocyte [nTPM]":"29.2","Blood RNA - MAIT T-cell [nTPM]":"47.8","Blood RNA - memory B-cell [nTPM]":"34.4","Blood RNA - memory CD4 T-cell [nTPM]":"43.8","Blood RNA - memory CD8 T-cell [nTPM]":"42.4","Blood RNA - myeloid DC [nTPM]":"31.3","Blood RNA - naive B-cell [nTPM]":"41.9","Blood RNA - naive CD4 T-cell [nTPM]":"74.9","Blood RNA - naive CD8 T-cell [nTPM]":"62.4","Blood RNA - neutrophil [nTPM]":"13.3","Blood RNA - NK-cell [nTPM]":"67.9","Blood RNA - non-classical monocyte [nTPM]":"26.3","Blood RNA - plasmacytoid DC [nTPM]":"59.2","Blood RNA - T-reg [nTPM]":"44.0","Blood RNA - total PBMC [nTPM]":"45.1","Brain RNA - amygdala [nTPM]":"53.2","Brain RNA - basal ganglia [nTPM]":"62.4","Brain RNA - cerebellum [nTPM]":"68.1","Brain RNA - cerebral cortex [nTPM]":"54.2","Brain RNA - hippocampal formation [nTPM]":"50.4","Brain RNA - hypothalamus [nTPM]":"61.3","Brain RNA - medulla oblongata [nTPM]":"69.0","Brain RNA - midbrain [nTPM]":"61.2","Brain RNA - pons [nTPM]":"66.0","Brain RNA - spinal cord [nTPM]":"68.6","Brain RNA - thalamus [nTPM]":"59.2","Brain RNA - white matter [nTPM]":"72.5","Single Cell Type RNA - Adipocytes [nTPM]":"28.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"22.8","Single Cell Type RNA - Astrocytes [nTPM]":"11.4","Single Cell Type RNA - B-cells [nTPM]":"31.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"64.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"53.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"15.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"24.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"47.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"24.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"35.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"90.6","Single Cell Type RNA - dendritic cells [nTPM]":"39.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"49.0","Single Cell Type RNA - Ductal cells [nTPM]":"50.0","Single Cell Type RNA - Early spermatids [nTPM]":"8.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"92.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"25.6","Single Cell Type RNA - Endothelial cells [nTPM]":"26.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"26.5","Single Cell Type RNA - Erythroid cells [nTPM]":"58.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"34.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"46.3","Single Cell Type RNA - Fibroblasts [nTPM]":"23.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"31.8","Single Cell Type RNA - granulocytes [nTPM]":"38.7","Single Cell Type RNA - Granulosa cells [nTPM]":"74.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.0","Single Cell Type RNA - Hepatocytes [nTPM]":"16.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"40.0","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.8","Single Cell Type RNA - Ionocytes [nTPM]":"57.0","Single Cell Type RNA - Kupffer cells [nTPM]":"20.4","Single Cell Type RNA - Langerhans cells [nTPM]":"19.8","Single Cell Type RNA - Late spermatids [nTPM]":"8.8","Single Cell Type RNA - Leydig cells [nTPM]":"38.2","Single Cell Type RNA - Macrophages [nTPM]":"31.5","Single Cell Type RNA - Melanocytes [nTPM]":"33.8","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"46.4","Single Cell Type RNA - Muller glia cells [nTPM]":"46.9","Single Cell Type RNA - NK-cells [nTPM]":"46.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"29.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.1","Single Cell Type RNA - Paneth cells [nTPM]":"15.8","Single Cell Type RNA - Peritubular cells [nTPM]":"37.6","Single Cell Type RNA - Plasma cells [nTPM]":"23.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"42.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"35.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"55.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"42.7","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"24.4","Single Cell Type RNA - Spermatocytes [nTPM]":"40.1","Single Cell Type RNA - Spermatogonia [nTPM]":"46.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"41.7","Single Cell Type RNA - T-cells [nTPM]":"34.9","Single Cell Type RNA - Theca cells [nTPM]":"44.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.1","Single Cell Type RNA - Urothelial cells [nTPM]":"40.4"},{"Gene":"PYGL","Gene synonym":["GSD6"],"Ensembl":"ENSG00000100504","Gene description":"Glycogen phosphorylase L","Uniprot":["P06737"],"Chromosome":"14","Position":"50857891-50944483","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism","Glycogen metabolism"],"Molecular function":["Allosteric enzyme","Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant","Glycogen storage disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"145.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"151.2","Hofbauer cells":"177.6","Muller glia cells":"265.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"141.1","neutrophil":"153.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"279.1","HMC-1":"304.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000962","HPA004119"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"16000000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 5: Muller glia cells - Visual perception","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA000962":"AB_1079722","HPA004119":"AB_1079723"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.64e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.97e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.63e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Tissue RNA - adipose tissue [nTPM]":"110.1","Tissue RNA - adrenal gland [nTPM]":"21.0","Tissue RNA - amygdala [nTPM]":"5.9","Tissue RNA - appendix [nTPM]":"24.1","Tissue RNA - basal ganglia [nTPM]":"6.6","Tissue RNA - bone marrow [nTPM]":"108.9","Tissue RNA - breast [nTPM]":"36.4","Tissue RNA - cerebellum [nTPM]":"5.0","Tissue RNA - cerebral cortex [nTPM]":"8.4","Tissue RNA - cervix [nTPM]":"33.6","Tissue RNA - choroid plexus [nTPM]":"10.4","Tissue RNA - colon [nTPM]":"19.0","Tissue RNA - duodenum [nTPM]":"3.7","Tissue RNA - endometrium 1 [nTPM]":"20.7","Tissue RNA - epididymis [nTPM]":"6.4","Tissue RNA - esophagus [nTPM]":"55.8","Tissue RNA - fallopian tube [nTPM]":"19.1","Tissue RNA - gallbladder [nTPM]":"13.0","Tissue RNA - heart muscle [nTPM]":"14.9","Tissue RNA - hippocampal formation [nTPM]":"5.2","Tissue RNA - hypothalamus [nTPM]":"6.2","Tissue RNA - kidney [nTPM]":"10.2","Tissue RNA - liver [nTPM]":"145.6","Tissue RNA - lung [nTPM]":"26.1","Tissue RNA - lymph node [nTPM]":"6.3","Tissue RNA - medulla oblongata [nTPM]":"10.7","Tissue RNA - midbrain [nTPM]":"17.6","Tissue RNA - ovary [nTPM]":"18.2","Tissue RNA - pancreas [nTPM]":"5.7","Tissue RNA - parathyroid gland [nTPM]":"21.1","Tissue RNA - pituitary gland [nTPM]":"7.5","Tissue RNA - placenta [nTPM]":"49.3","Tissue RNA - pons [nTPM]":"8.7","Tissue RNA - prostate [nTPM]":"13.0","Tissue RNA - rectum [nTPM]":"24.0","Tissue RNA - retina [nTPM]":"78.2","Tissue RNA - salivary gland [nTPM]":"26.8","Tissue RNA - seminal vesicle [nTPM]":"29.7","Tissue RNA - skeletal muscle [nTPM]":"5.1","Tissue RNA - skin 1 [nTPM]":"37.0","Tissue RNA - small intestine [nTPM]":"8.4","Tissue RNA - smooth muscle [nTPM]":"26.7","Tissue RNA - spinal cord [nTPM]":"8.6","Tissue RNA - spleen [nTPM]":"49.4","Tissue RNA - stomach 1 [nTPM]":"9.6","Tissue RNA - testis [nTPM]":"5.2","Tissue RNA - thalamus [nTPM]":"9.0","Tissue RNA - thymus [nTPM]":"4.8","Tissue RNA - thyroid gland [nTPM]":"10.2","Tissue RNA - tongue [nTPM]":"5.8","Tissue RNA - tonsil [nTPM]":"6.8","Tissue RNA - urinary bladder [nTPM]":"41.7","Tissue RNA - vagina [nTPM]":"38.1","Tissue RNA - white matter [nTPM]":"10.3","Cell RNA - A-431 [nTPM]":"145.7","Cell RNA - A549 [nTPM]":"40.8","Cell RNA - AF22 [nTPM]":"10.1","Cell RNA - AN3-CA [nTPM]":"64.3","Cell RNA - ASC diff [nTPM]":"47.0","Cell RNA - ASC TERT1 [nTPM]":"56.2","Cell RNA - BEWO [nTPM]":"114.5","Cell RNA - BJ [nTPM]":"28.6","Cell RNA - BJ hTERT+ [nTPM]":"24.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"77.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"117.3","Cell RNA - CACO-2 [nTPM]":"107.4","Cell RNA - CAPAN-2 [nTPM]":"18.3","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"54.4","Cell RNA - fHDF\/TERT166 [nTPM]":"171.7","Cell RNA - GAMG [nTPM]":"91.2","Cell RNA - HaCaT [nTPM]":"279.1","Cell RNA - HAP1 [nTPM]":"107.0","Cell RNA - HBEC3-KT [nTPM]":"144.8","Cell RNA - HBF TERT88 [nTPM]":"132.0","Cell RNA - HDLM-2 [nTPM]":"0.5","Cell RNA - HEK 293 [nTPM]":"46.8","Cell RNA - HEL [nTPM]":"28.0","Cell RNA - HeLa [nTPM]":"60.5","Cell RNA - Hep G2 [nTPM]":"82.4","Cell RNA - HHSteC [nTPM]":"83.8","Cell RNA - HL-60 [nTPM]":"106.9","Cell RNA - HMC-1 [nTPM]":"304.4","Cell RNA - HSkMC [nTPM]":"119.4","Cell RNA - hTCEpi [nTPM]":"56.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"104.1","Cell RNA - hTERT-HME1 [nTPM]":"43.6","Cell RNA - hTERT-RPE1 [nTPM]":"75.4","Cell RNA - HUVEC TERT2 [nTPM]":"69.3","Cell RNA - JURKAT [nTPM]":"0.8","Cell RNA - K-562 [nTPM]":"11.6","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"55.4","Cell RNA - MCF7 [nTPM]":"144.7","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"141.7","Cell RNA - NTERA-2 [nTPM]":"39.3","Cell RNA - OE19 [nTPM]":"12.8","Cell RNA - PC-3 [nTPM]":"152.0","Cell RNA - REH [nTPM]":"2.7","Cell RNA - RH-30 [nTPM]":"36.2","Cell RNA - RPMI-8226 [nTPM]":"6.1","Cell RNA - RPTEC TERT1 [nTPM]":"104.7","Cell RNA - RT4 [nTPM]":"95.1","Cell RNA - SCLC-21H [nTPM]":"4.5","Cell RNA - SH-SY5Y [nTPM]":"4.4","Cell RNA - SiHa [nTPM]":"131.0","Cell RNA - SK-BR-3 [nTPM]":"43.3","Cell RNA - SK-MEL-30 [nTPM]":"1.7","Cell RNA - SuSa [nTPM]":"38.6","Cell RNA - T-47d [nTPM]":"20.6","Cell RNA - THP-1 [nTPM]":"200.4","Cell RNA - TIME [nTPM]":"3.2","Cell RNA - U-138 MG [nTPM]":"29.7","Cell RNA - U-2 OS [nTPM]":"49.6","Cell RNA - U-2197 [nTPM]":"56.0","Cell RNA - U-251 MG [nTPM]":"92.9","Cell RNA - U-266\/70 [nTPM]":"1.2","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"27.3","Cell RNA - U-937 [nTPM]":"107.7","Cell RNA - WM-115 [nTPM]":"15.9","Blood RNA - basophil [nTPM]":"50.2","Blood RNA - classical monocyte [nTPM]":"55.9","Blood RNA - eosinophil [nTPM]":"141.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"24.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"27.3","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"153.7","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"15.7","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"24.8","Brain RNA - amygdala [nTPM]":"5.9","Brain RNA - basal ganglia [nTPM]":"6.6","Brain RNA - cerebellum [nTPM]":"5.0","Brain RNA - cerebral cortex [nTPM]":"8.4","Brain RNA - hippocampal formation [nTPM]":"5.2","Brain RNA - hypothalamus [nTPM]":"6.2","Brain RNA - medulla oblongata [nTPM]":"10.7","Brain RNA - midbrain [nTPM]":"17.6","Brain RNA - pons [nTPM]":"8.7","Brain RNA - spinal cord [nTPM]":"8.6","Brain RNA - thalamus [nTPM]":"9.0","Brain RNA - white matter [nTPM]":"10.3","Single Cell Type RNA - Adipocytes [nTPM]":"6.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.3","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"1.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"40.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"4.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"35.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"28.9","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"10.9","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"35.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.9","Single Cell Type RNA - Endothelial cells [nTPM]":"7.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"9.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"151.2","Single Cell Type RNA - Fibroblasts [nTPM]":"18.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"62.6","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"9.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.2","Single Cell Type RNA - Hepatocytes [nTPM]":"65.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"177.6","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.1","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"56.7","Single Cell Type RNA - Langerhans cells [nTPM]":"7.9","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"14.3","Single Cell Type RNA - Macrophages [nTPM]":"54.6","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"52.4","Single Cell Type RNA - Muller glia cells [nTPM]":"265.1","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.4","Single Cell Type RNA - Paneth cells [nTPM]":"5.2","Single Cell Type RNA - Peritubular cells [nTPM]":"21.8","Single Cell Type RNA - Plasma cells [nTPM]":"1.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"24.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"1.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"21.1","Single Cell Type RNA - T-cells [nTPM]":"2.3","Single Cell Type RNA - Theca cells [nTPM]":"4.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.0","Single Cell Type RNA - Urothelial cells [nTPM]":"9.2"},{"Gene":"PYGM","Gene synonym":["GSD5"],"Ensembl":"ENSG00000068976","Gene description":"Glycogen phosphorylase, muscle associated","Uniprot":["P11217"],"Chromosome":"11","Position":"64746389-64759974","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism","Glycogen metabolism"],"Molecular function":["Allosteric enzyme","Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant","Glycogen storage disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"65","RNA tissue specific nTPM":{"skeletal muscle":"8468.3","tongue":"3594.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"29.7","Cardiomyocytes":"47.5","Late spermatids":"49.2","Peritubular cells":"44.0","Skeletal myocytes":"64.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"8.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"8.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HSkMC":"3.7","NB-4":"2.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056003"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"10000000","Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 37: Myocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA056003":"AB_2683006"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.2","Tissue RNA - adrenal gland [nTPM]":"3.0","Tissue RNA - amygdala [nTPM]":"35.4","Tissue RNA - appendix [nTPM]":"2.1","Tissue RNA - basal ganglia [nTPM]":"30.1","Tissue RNA - bone marrow [nTPM]":"1.2","Tissue RNA - breast [nTPM]":"7.7","Tissue RNA - cerebellum [nTPM]":"55.5","Tissue RNA - cerebral cortex [nTPM]":"29.4","Tissue RNA - cervix [nTPM]":"5.8","Tissue RNA - choroid plexus [nTPM]":"15.5","Tissue RNA - colon [nTPM]":"25.5","Tissue RNA - duodenum [nTPM]":"1.5","Tissue RNA - endometrium 1 [nTPM]":"10.4","Tissue RNA - epididymis [nTPM]":"6.4","Tissue RNA - esophagus [nTPM]":"92.2","Tissue RNA - fallopian tube [nTPM]":"14.6","Tissue RNA - gallbladder [nTPM]":"3.8","Tissue RNA - heart muscle [nTPM]":"70.8","Tissue RNA - hippocampal formation [nTPM]":"26.8","Tissue RNA - hypothalamus [nTPM]":"26.1","Tissue RNA - kidney [nTPM]":"2.4","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"2.7","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"48.8","Tissue RNA - midbrain [nTPM]":"30.4","Tissue RNA - ovary [nTPM]":"4.0","Tissue RNA - pancreas [nTPM]":"1.6","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"1.7","Tissue RNA - placenta [nTPM]":"1.4","Tissue RNA - pons [nTPM]":"39.6","Tissue RNA - prostate [nTPM]":"25.6","Tissue RNA - rectum [nTPM]":"3.6","Tissue RNA - retina [nTPM]":"2.9","Tissue RNA - salivary gland [nTPM]":"50.0","Tissue RNA - seminal vesicle [nTPM]":"26.3","Tissue RNA - skeletal muscle [nTPM]":"8468.3","Tissue RNA - skin 1 [nTPM]":"4.2","Tissue RNA - small intestine [nTPM]":"7.0","Tissue RNA - smooth muscle [nTPM]":"14.7","Tissue RNA - spinal cord [nTPM]":"44.9","Tissue RNA - spleen [nTPM]":"3.3","Tissue RNA - stomach 1 [nTPM]":"6.9","Tissue RNA - testis [nTPM]":"6.7","Tissue RNA - thalamus [nTPM]":"47.3","Tissue RNA - thymus [nTPM]":"1.3","Tissue RNA - thyroid gland [nTPM]":"5.2","Tissue RNA - tongue [nTPM]":"3594.2","Tissue RNA - tonsil [nTPM]":"1.2","Tissue RNA - urinary bladder [nTPM]":"16.7","Tissue RNA - vagina [nTPM]":"5.2","Tissue RNA - white matter [nTPM]":"38.1","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.7","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.5","Cell RNA - ASC TERT1 [nTPM]":"0.7","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"0.6","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.6","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"3.7","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"1.1","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"0.6","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.1","Cell RNA - MOLT-4 [nTPM]":"0.7","Cell RNA - NB-4 [nTPM]":"2.2","Cell RNA - NTERA-2 [nTPM]":"0.7","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"0.7","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"1.0","Cell RNA - U-266\/84 [nTPM]":"1.4","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"8.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"1.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"35.4","Brain RNA - basal ganglia [nTPM]":"30.1","Brain RNA - cerebellum [nTPM]":"55.5","Brain RNA - cerebral cortex [nTPM]":"29.4","Brain RNA - hippocampal formation [nTPM]":"26.8","Brain RNA - hypothalamus [nTPM]":"26.1","Brain RNA - medulla oblongata [nTPM]":"48.8","Brain RNA - midbrain [nTPM]":"30.4","Brain RNA - pons [nTPM]":"39.6","Brain RNA - spinal cord [nTPM]":"44.9","Brain RNA - thalamus [nTPM]":"47.3","Brain RNA - white matter [nTPM]":"38.1","Single Cell Type RNA - Adipocytes [nTPM]":"2.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.3","Single Cell Type RNA - Astrocytes [nTPM]":"29.7","Single Cell Type RNA - B-cells [nTPM]":"3.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"3.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"47.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.6","Single Cell Type RNA - dendritic cells [nTPM]":"1.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"11.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.2","Single Cell Type RNA - Endothelial cells [nTPM]":"2.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"5.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"1.3","Single Cell Type RNA - Late spermatids [nTPM]":"49.2","Single Cell Type RNA - Leydig cells [nTPM]":"16.4","Single Cell Type RNA - Macrophages [nTPM]":"2.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.5","Single Cell Type RNA - Muller glia cells [nTPM]":"9.9","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.2","Single Cell Type RNA - Peritubular cells [nTPM]":"44.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"64.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.8","Single Cell Type RNA - Spermatocytes [nTPM]":"1.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"2.9","Single Cell Type RNA - Theca cells [nTPM]":"0.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"QARS1","Gene synonym":["QARS"],"Ensembl":"ENSG00000172053","Gene description":"Glutaminyl-tRNA synthetase 1","Uniprot":["P47897"],"Chromosome":"3","Position":"49095932-49105130","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Disease variant","Epilepsy","Primary microcephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Cardiomyocytes":"55.5","Cytotrophoblasts":"193.9","Extravillous trophoblasts":"156.7","Hofbauer cells":"96.1","Syncytiotrophoblasts":"187.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036986","HPA036987"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"58000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA036986":"AB_10672344","HPA036987":"AB_2675418"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.43e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.60e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"},"Tissue RNA - adipose tissue [nTPM]":"61.1","Tissue RNA - adrenal gland [nTPM]":"58.8","Tissue RNA - amygdala [nTPM]":"20.0","Tissue RNA - appendix [nTPM]":"57.2","Tissue RNA - basal ganglia [nTPM]":"21.3","Tissue RNA - bone marrow [nTPM]":"96.6","Tissue RNA - breast [nTPM]":"89.5","Tissue RNA - cerebellum [nTPM]":"23.5","Tissue RNA - cerebral cortex [nTPM]":"18.5","Tissue RNA - cervix [nTPM]":"58.3","Tissue RNA - choroid plexus [nTPM]":"34.2","Tissue RNA - colon [nTPM]":"104.8","Tissue RNA - duodenum [nTPM]":"101.6","Tissue RNA - endometrium 1 [nTPM]":"45.5","Tissue RNA - epididymis [nTPM]":"58.5","Tissue RNA - esophagus [nTPM]":"102.5","Tissue RNA - fallopian tube [nTPM]":"71.0","Tissue RNA - gallbladder [nTPM]":"48.3","Tissue RNA - heart muscle [nTPM]":"72.0","Tissue RNA - hippocampal formation [nTPM]":"18.4","Tissue RNA - hypothalamus [nTPM]":"21.1","Tissue RNA - kidney [nTPM]":"57.1","Tissue RNA - liver [nTPM]":"51.1","Tissue RNA - lung [nTPM]":"52.3","Tissue RNA - lymph node [nTPM]":"75.8","Tissue RNA - medulla oblongata [nTPM]":"23.8","Tissue RNA - midbrain [nTPM]":"21.0","Tissue RNA - ovary [nTPM]":"69.0","Tissue RNA - pancreas [nTPM]":"73.9","Tissue RNA - parathyroid gland [nTPM]":"78.1","Tissue RNA - pituitary gland [nTPM]":"33.0","Tissue RNA - placenta [nTPM]":"76.7","Tissue RNA - pons [nTPM]":"23.0","Tissue RNA - prostate [nTPM]":"60.4","Tissue RNA - rectum [nTPM]":"121.0","Tissue RNA - retina [nTPM]":"21.4","Tissue RNA - salivary gland [nTPM]":"103.2","Tissue RNA - seminal vesicle [nTPM]":"61.1","Tissue RNA - skeletal muscle [nTPM]":"156.1","Tissue RNA - skin 1 [nTPM]":"105.0","Tissue RNA - small intestine [nTPM]":"84.6","Tissue RNA - smooth muscle [nTPM]":"60.2","Tissue RNA - spinal cord [nTPM]":"22.7","Tissue RNA - spleen [nTPM]":"60.1","Tissue RNA - stomach 1 [nTPM]":"75.0","Tissue RNA - testis [nTPM]":"30.0","Tissue RNA - thalamus [nTPM]":"23.0","Tissue RNA - thymus [nTPM]":"92.3","Tissue RNA - thyroid gland [nTPM]":"53.2","Tissue RNA - tongue [nTPM]":"146.2","Tissue RNA - tonsil [nTPM]":"118.8","Tissue RNA - urinary bladder [nTPM]":"72.8","Tissue RNA - vagina [nTPM]":"58.1","Tissue RNA - white matter [nTPM]":"24.6","Cell RNA - A-431 [nTPM]":"95.9","Cell RNA - A549 [nTPM]":"97.8","Cell RNA - AF22 [nTPM]":"128.0","Cell RNA - AN3-CA [nTPM]":"197.4","Cell RNA - ASC diff [nTPM]":"146.4","Cell RNA - ASC TERT1 [nTPM]":"180.8","Cell RNA - BEWO [nTPM]":"159.2","Cell RNA - BJ [nTPM]":"90.5","Cell RNA - BJ hTERT+ [nTPM]":"188.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"160.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"152.9","Cell RNA - CACO-2 [nTPM]":"123.0","Cell RNA - CAPAN-2 [nTPM]":"113.5","Cell RNA - Daudi [nTPM]":"257.1","Cell RNA - EFO-21 [nTPM]":"61.4","Cell RNA - fHDF\/TERT166 [nTPM]":"136.7","Cell RNA - GAMG [nTPM]":"95.3","Cell RNA - HaCaT [nTPM]":"119.9","Cell RNA - HAP1 [nTPM]":"166.3","Cell RNA - HBEC3-KT [nTPM]":"137.8","Cell RNA - HBF TERT88 [nTPM]":"111.4","Cell RNA - HDLM-2 [nTPM]":"78.2","Cell RNA - HEK 293 [nTPM]":"148.0","Cell RNA - HEL [nTPM]":"206.4","Cell RNA - HeLa [nTPM]":"156.0","Cell RNA - Hep G2 [nTPM]":"216.1","Cell RNA - HHSteC [nTPM]":"91.2","Cell RNA - HL-60 [nTPM]":"187.2","Cell RNA - HMC-1 [nTPM]":"130.9","Cell RNA - HSkMC [nTPM]":"184.8","Cell RNA - hTCEpi [nTPM]":"123.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"127.4","Cell RNA - hTERT-HME1 [nTPM]":"108.1","Cell RNA - hTERT-RPE1 [nTPM]":"175.3","Cell RNA - HUVEC TERT2 [nTPM]":"184.7","Cell RNA - JURKAT [nTPM]":"144.6","Cell RNA - K-562 [nTPM]":"95.3","Cell RNA - Karpas-707 [nTPM]":"112.4","Cell RNA - LHCN-M2 [nTPM]":"118.0","Cell RNA - MCF7 [nTPM]":"89.2","Cell RNA - MOLT-4 [nTPM]":"130.7","Cell RNA - NB-4 [nTPM]":"154.9","Cell RNA - NTERA-2 [nTPM]":"116.1","Cell RNA - OE19 [nTPM]":"159.0","Cell RNA - PC-3 [nTPM]":"122.9","Cell RNA - REH [nTPM]":"76.0","Cell RNA - RH-30 [nTPM]":"123.7","Cell RNA - RPMI-8226 [nTPM]":"200.6","Cell RNA - RPTEC TERT1 [nTPM]":"108.5","Cell RNA - RT4 [nTPM]":"163.9","Cell RNA - SCLC-21H [nTPM]":"48.7","Cell RNA - SH-SY5Y [nTPM]":"161.6","Cell RNA - SiHa [nTPM]":"85.4","Cell RNA - SK-BR-3 [nTPM]":"211.0","Cell RNA - SK-MEL-30 [nTPM]":"147.8","Cell RNA - SuSa [nTPM]":"122.7","Cell RNA - T-47d [nTPM]":"184.4","Cell RNA - THP-1 [nTPM]":"205.5","Cell RNA - TIME [nTPM]":"137.6","Cell RNA - U-138 MG [nTPM]":"82.8","Cell RNA - U-2 OS [nTPM]":"127.3","Cell RNA - U-2197 [nTPM]":"131.7","Cell RNA - U-251 MG [nTPM]":"117.9","Cell RNA - U-266\/70 [nTPM]":"111.9","Cell RNA - U-266\/84 [nTPM]":"176.5","Cell RNA - U-698 [nTPM]":"142.9","Cell RNA - U-87 MG [nTPM]":"88.4","Cell RNA - U-937 [nTPM]":"156.3","Cell RNA - WM-115 [nTPM]":"60.3","Blood RNA - basophil [nTPM]":"30.7","Blood RNA - classical monocyte [nTPM]":"84.3","Blood RNA - eosinophil [nTPM]":"25.8","Blood RNA - gdT-cell [nTPM]":"44.5","Blood RNA - intermediate monocyte [nTPM]":"104.1","Blood RNA - MAIT T-cell [nTPM]":"57.4","Blood RNA - memory B-cell [nTPM]":"62.2","Blood RNA - memory CD4 T-cell [nTPM]":"54.1","Blood RNA - memory CD8 T-cell [nTPM]":"47.0","Blood RNA - myeloid DC [nTPM]":"127.0","Blood RNA - naive B-cell [nTPM]":"49.9","Blood RNA - naive CD4 T-cell [nTPM]":"46.6","Blood RNA - naive CD8 T-cell [nTPM]":"49.0","Blood RNA - neutrophil [nTPM]":"8.0","Blood RNA - NK-cell [nTPM]":"71.8","Blood RNA - non-classical monocyte [nTPM]":"94.5","Blood RNA - plasmacytoid DC [nTPM]":"57.4","Blood RNA - T-reg [nTPM]":"82.1","Blood RNA - total PBMC [nTPM]":"81.2","Brain RNA - amygdala [nTPM]":"20.0","Brain RNA - basal ganglia [nTPM]":"21.3","Brain RNA - cerebellum [nTPM]":"23.5","Brain RNA - cerebral cortex [nTPM]":"18.5","Brain RNA - hippocampal formation [nTPM]":"18.4","Brain RNA - hypothalamus [nTPM]":"21.1","Brain RNA - medulla oblongata [nTPM]":"23.8","Brain RNA - midbrain [nTPM]":"21.0","Brain RNA - pons [nTPM]":"23.0","Brain RNA - spinal cord [nTPM]":"22.7","Brain RNA - thalamus [nTPM]":"23.0","Brain RNA - white matter [nTPM]":"24.6","Single Cell Type RNA - Adipocytes [nTPM]":"15.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"4.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"55.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"193.9","Single Cell Type RNA - dendritic cells [nTPM]":"11.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"9.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"156.7","Single Cell Type RNA - Fibroblasts [nTPM]":"14.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"96.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"4.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"5.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"187.0","Single Cell Type RNA - T-cells [nTPM]":"2.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"QDPR","Gene synonym":["DHPR","PKU2","SDR33C1"],"Ensembl":"ENSG00000151552","Gene description":"Quinoid dihydropteridine reductase","Uniprot":["P09417"],"Chromosome":"4","Position":"17460261-17512206","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Tetrahydrobiopterin biosynthesis"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Phenylketonuria"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"752.2","choroid plexus":"301.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"337.6","Muller glia cells":"387.2","Oligodendrocytes":"481.3","Proximal tubular cells":"527.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058951","HPA065649"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2500000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA058951":"AB_2683861","HPA065649":"AB_2685526"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.84e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Tissue RNA - adipose tissue [nTPM]":"66.6","Tissue RNA - adrenal gland [nTPM]":"74.3","Tissue RNA - amygdala [nTPM]":"515.1","Tissue RNA - appendix [nTPM]":"10.2","Tissue RNA - basal ganglia [nTPM]":"720.1","Tissue RNA - bone marrow [nTPM]":"15.1","Tissue RNA - breast [nTPM]":"26.4","Tissue RNA - cerebellum [nTPM]":"696.9","Tissue RNA - cerebral cortex [nTPM]":"571.9","Tissue RNA - cervix [nTPM]":"15.8","Tissue RNA - choroid plexus [nTPM]":"301.8","Tissue RNA - colon [nTPM]":"21.2","Tissue RNA - duodenum [nTPM]":"25.6","Tissue RNA - endometrium 1 [nTPM]":"16.5","Tissue RNA - epididymis [nTPM]":"40.1","Tissue RNA - esophagus [nTPM]":"15.6","Tissue RNA - fallopian tube [nTPM]":"17.3","Tissue RNA - gallbladder [nTPM]":"17.7","Tissue RNA - heart muscle [nTPM]":"43.4","Tissue RNA - hippocampal formation [nTPM]":"457.6","Tissue RNA - hypothalamus [nTPM]":"578.5","Tissue RNA - kidney [nTPM]":"110.1","Tissue RNA - liver [nTPM]":"197.2","Tissue RNA - lung [nTPM]":"23.3","Tissue RNA - lymph node [nTPM]":"11.9","Tissue RNA - medulla oblongata [nTPM]":"663.0","Tissue RNA - midbrain [nTPM]":"752.2","Tissue RNA - ovary [nTPM]":"18.3","Tissue RNA - pancreas [nTPM]":"28.8","Tissue RNA - parathyroid gland [nTPM]":"49.9","Tissue RNA - pituitary gland [nTPM]":"32.7","Tissue RNA - placenta [nTPM]":"11.8","Tissue RNA - pons [nTPM]":"688.6","Tissue RNA - prostate [nTPM]":"28.7","Tissue RNA - rectum [nTPM]":"17.0","Tissue RNA - retina [nTPM]":"40.1","Tissue RNA - salivary gland [nTPM]":"36.3","Tissue RNA - seminal vesicle [nTPM]":"19.5","Tissue RNA - skeletal muscle [nTPM]":"108.6","Tissue RNA - skin 1 [nTPM]":"16.2","Tissue RNA - small intestine [nTPM]":"23.9","Tissue RNA - smooth muscle [nTPM]":"17.9","Tissue RNA - spinal cord [nTPM]":"524.9","Tissue RNA - spleen [nTPM]":"14.3","Tissue RNA - stomach 1 [nTPM]":"23.7","Tissue RNA - testis [nTPM]":"12.4","Tissue RNA - thalamus [nTPM]":"602.6","Tissue RNA - thymus [nTPM]":"13.6","Tissue RNA - thyroid gland [nTPM]":"22.1","Tissue RNA - tongue [nTPM]":"61.2","Tissue RNA - tonsil [nTPM]":"13.3","Tissue RNA - urinary bladder [nTPM]":"14.5","Tissue RNA - vagina [nTPM]":"15.1","Tissue RNA - white matter [nTPM]":"663.7","Cell RNA - A-431 [nTPM]":"33.1","Cell RNA - A549 [nTPM]":"62.5","Cell RNA - AF22 [nTPM]":"30.2","Cell RNA - AN3-CA [nTPM]":"35.8","Cell RNA - ASC diff [nTPM]":"66.1","Cell RNA - ASC TERT1 [nTPM]":"32.3","Cell RNA - BEWO [nTPM]":"41.5","Cell RNA - BJ [nTPM]":"43.2","Cell RNA - BJ hTERT+ [nTPM]":"22.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"47.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"41.6","Cell RNA - CACO-2 [nTPM]":"52.2","Cell RNA - CAPAN-2 [nTPM]":"46.4","Cell RNA - Daudi [nTPM]":"12.2","Cell RNA - EFO-21 [nTPM]":"28.0","Cell RNA - fHDF\/TERT166 [nTPM]":"30.3","Cell RNA - GAMG [nTPM]":"50.8","Cell RNA - HaCaT [nTPM]":"18.4","Cell RNA - HAP1 [nTPM]":"40.3","Cell RNA - HBEC3-KT [nTPM]":"58.4","Cell RNA - HBF TERT88 [nTPM]":"33.7","Cell RNA - HDLM-2 [nTPM]":"35.3","Cell RNA - HEK 293 [nTPM]":"7.3","Cell RNA - HEL [nTPM]":"34.8","Cell RNA - HeLa [nTPM]":"33.4","Cell RNA - Hep G2 [nTPM]":"128.3","Cell RNA - HHSteC [nTPM]":"37.3","Cell RNA - HL-60 [nTPM]":"46.2","Cell RNA - HMC-1 [nTPM]":"2.9","Cell RNA - HSkMC [nTPM]":"40.8","Cell RNA - hTCEpi [nTPM]":"35.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"31.6","Cell RNA - hTERT-HME1 [nTPM]":"40.3","Cell RNA - hTERT-RPE1 [nTPM]":"25.9","Cell RNA - HUVEC TERT2 [nTPM]":"24.5","Cell RNA - JURKAT [nTPM]":"33.2","Cell RNA - K-562 [nTPM]":"37.0","Cell RNA - Karpas-707 [nTPM]":"29.0","Cell RNA - LHCN-M2 [nTPM]":"50.6","Cell RNA - MCF7 [nTPM]":"19.2","Cell RNA - MOLT-4 [nTPM]":"65.0","Cell RNA - NB-4 [nTPM]":"77.8","Cell RNA - NTERA-2 [nTPM]":"44.8","Cell RNA - OE19 [nTPM]":"36.7","Cell RNA - PC-3 [nTPM]":"45.4","Cell RNA - REH [nTPM]":"27.0","Cell RNA - RH-30 [nTPM]":"21.0","Cell RNA - RPMI-8226 [nTPM]":"52.2","Cell RNA - RPTEC TERT1 [nTPM]":"48.2","Cell RNA - RT4 [nTPM]":"17.5","Cell RNA - SCLC-21H [nTPM]":"47.1","Cell RNA - SH-SY5Y [nTPM]":"64.3","Cell RNA - SiHa [nTPM]":"31.9","Cell RNA - SK-BR-3 [nTPM]":"6.7","Cell RNA - SK-MEL-30 [nTPM]":"156.6","Cell RNA - SuSa [nTPM]":"35.0","Cell RNA - T-47d [nTPM]":"15.7","Cell RNA - THP-1 [nTPM]":"19.0","Cell RNA - TIME [nTPM]":"37.7","Cell RNA - U-138 MG [nTPM]":"23.6","Cell RNA - U-2 OS [nTPM]":"41.1","Cell RNA - U-2197 [nTPM]":"26.5","Cell RNA - U-251 MG [nTPM]":"38.2","Cell RNA - U-266\/70 [nTPM]":"43.1","Cell RNA - U-266\/84 [nTPM]":"67.7","Cell RNA - U-698 [nTPM]":"85.3","Cell RNA - U-87 MG [nTPM]":"52.0","Cell RNA - U-937 [nTPM]":"43.1","Cell RNA - WM-115 [nTPM]":"41.7","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"38.9","Blood RNA - eosinophil [nTPM]":"3.0","Blood RNA - gdT-cell [nTPM]":"31.3","Blood RNA - intermediate monocyte [nTPM]":"61.3","Blood RNA - MAIT T-cell [nTPM]":"29.8","Blood RNA - memory B-cell [nTPM]":"18.6","Blood RNA - memory CD4 T-cell [nTPM]":"33.1","Blood RNA - memory CD8 T-cell [nTPM]":"32.3","Blood RNA - myeloid DC [nTPM]":"48.3","Blood RNA - naive B-cell [nTPM]":"18.3","Blood RNA - naive CD4 T-cell [nTPM]":"37.4","Blood RNA - naive CD8 T-cell [nTPM]":"32.6","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"29.8","Blood RNA - non-classical monocyte [nTPM]":"48.4","Blood RNA - plasmacytoid DC [nTPM]":"115.1","Blood RNA - T-reg [nTPM]":"20.3","Blood RNA - total PBMC [nTPM]":"34.4","Brain RNA - amygdala [nTPM]":"515.1","Brain RNA - basal ganglia [nTPM]":"720.1","Brain RNA - cerebellum [nTPM]":"696.9","Brain RNA - cerebral cortex [nTPM]":"571.9","Brain RNA - hippocampal formation [nTPM]":"457.6","Brain RNA - hypothalamus [nTPM]":"578.5","Brain RNA - medulla oblongata [nTPM]":"663.0","Brain RNA - midbrain [nTPM]":"752.2","Brain RNA - pons [nTPM]":"688.6","Brain RNA - spinal cord [nTPM]":"524.9","Brain RNA - thalamus [nTPM]":"602.6","Brain RNA - white matter [nTPM]":"663.7","Single Cell Type RNA - Adipocytes [nTPM]":"20.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.5","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"14.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"32.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Bipolar cells [nTPM]":"36.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"37.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"28.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"74.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"50.1","Single Cell Type RNA - Club cells [nTPM]":"19.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"69.6","Single Cell Type RNA - dendritic cells [nTPM]":"22.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"109.5","Single Cell Type RNA - Ductal cells [nTPM]":"41.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.1","Single Cell Type RNA - Endothelial cells [nTPM]":"17.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"174.3","Single Cell Type RNA - Erythroid cells [nTPM]":"30.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"34.2","Single Cell Type RNA - Fibroblasts [nTPM]":"27.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"27.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.8","Single Cell Type RNA - granulocytes [nTPM]":"25.4","Single Cell Type RNA - Granulosa cells [nTPM]":"42.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.7","Single Cell Type RNA - Hepatocytes [nTPM]":"337.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"80.3","Single Cell Type RNA - Horizontal cells [nTPM]":"82.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.1","Single Cell Type RNA - Ionocytes [nTPM]":"34.6","Single Cell Type RNA - Kupffer cells [nTPM]":"38.1","Single Cell Type RNA - Langerhans cells [nTPM]":"23.9","Single Cell Type RNA - Late spermatids [nTPM]":"4.8","Single Cell Type RNA - Leydig cells [nTPM]":"22.7","Single Cell Type RNA - Macrophages [nTPM]":"32.2","Single Cell Type RNA - Melanocytes [nTPM]":"152.9","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"23.4","Single Cell Type RNA - Muller glia cells [nTPM]":"387.2","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"481.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.9","Single Cell Type RNA - Paneth cells [nTPM]":"11.6","Single Cell Type RNA - Peritubular cells [nTPM]":"38.0","Single Cell Type RNA - Plasma cells [nTPM]":"23.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"41.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"527.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"31.4","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"25.4","Single Cell Type RNA - Spermatocytes [nTPM]":"3.3","Single Cell Type RNA - Spermatogonia [nTPM]":"58.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"29.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"18.3","Single Cell Type RNA - T-cells [nTPM]":"18.5","Single Cell Type RNA - Theca cells [nTPM]":"90.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"35.7","Single Cell Type RNA - Urothelial cells [nTPM]":"17.3"},{"Gene":"QRSL1","Gene synonym":["DKFZP564C1278","FLJ10989","FLJ12189","FLJ13447","GatA"],"Ensembl":"ENSG00000130348","Gene description":"Glutaminyl-tRNA amidotransferase subunit QRSL1","Uniprot":["Q9H0R6"],"Chromosome":"6","Position":"106629578-106668417","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Ligase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"64.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"memory B-cell":"86.4","naive B-cell":"71.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"B-cells":"86.4"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029585","HPA029587"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"HPA029585":"AB_10599823","HPA029587":"AB_10602311"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.97e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.83e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.0","Tissue RNA - adrenal gland [nTPM]":"5.7","Tissue RNA - amygdala [nTPM]":"4.0","Tissue RNA - appendix [nTPM]":"8.6","Tissue RNA - basal ganglia [nTPM]":"5.2","Tissue RNA - bone marrow [nTPM]":"6.4","Tissue RNA - breast [nTPM]":"7.4","Tissue RNA - cerebellum [nTPM]":"4.7","Tissue RNA - cerebral cortex [nTPM]":"5.0","Tissue RNA - cervix [nTPM]":"4.8","Tissue RNA - choroid plexus [nTPM]":"5.8","Tissue RNA - colon [nTPM]":"8.2","Tissue RNA - duodenum [nTPM]":"7.8","Tissue RNA - endometrium 1 [nTPM]":"6.3","Tissue RNA - epididymis [nTPM]":"6.1","Tissue RNA - esophagus [nTPM]":"5.7","Tissue RNA - fallopian tube [nTPM]":"5.4","Tissue RNA - gallbladder [nTPM]":"4.8","Tissue RNA - heart muscle [nTPM]":"10.1","Tissue RNA - hippocampal formation [nTPM]":"4.1","Tissue RNA - hypothalamus [nTPM]":"4.5","Tissue RNA - kidney [nTPM]":"9.3","Tissue RNA - liver [nTPM]":"7.8","Tissue RNA - lung [nTPM]":"4.6","Tissue RNA - lymph node [nTPM]":"15.9","Tissue RNA - medulla oblongata [nTPM]":"4.6","Tissue RNA - midbrain [nTPM]":"4.5","Tissue RNA - ovary [nTPM]":"5.6","Tissue RNA - pancreas [nTPM]":"6.0","Tissue RNA - parathyroid gland [nTPM]":"9.4","Tissue RNA - pituitary gland [nTPM]":"4.3","Tissue RNA - placenta [nTPM]":"5.7","Tissue RNA - pons [nTPM]":"5.0","Tissue RNA - prostate [nTPM]":"5.3","Tissue RNA - rectum [nTPM]":"9.1","Tissue RNA - retina [nTPM]":"8.4","Tissue RNA - salivary gland [nTPM]":"6.1","Tissue RNA - seminal vesicle [nTPM]":"5.6","Tissue RNA - skeletal muscle [nTPM]":"19.4","Tissue RNA - skin 1 [nTPM]":"5.9","Tissue RNA - small intestine [nTPM]":"8.9","Tissue RNA - smooth muscle [nTPM]":"5.8","Tissue RNA - spinal cord [nTPM]":"4.1","Tissue RNA - spleen [nTPM]":"10.5","Tissue RNA - stomach 1 [nTPM]":"6.7","Tissue RNA - testis [nTPM]":"6.6","Tissue RNA - thalamus [nTPM]":"4.5","Tissue RNA - thymus [nTPM]":"8.2","Tissue RNA - thyroid gland [nTPM]":"9.2","Tissue RNA - tongue [nTPM]":"21.3","Tissue RNA - tonsil [nTPM]":"15.5","Tissue RNA - urinary bladder [nTPM]":"5.7","Tissue RNA - vagina [nTPM]":"4.9","Tissue RNA - white matter [nTPM]":"7.4","Cell RNA - A-431 [nTPM]":"9.0","Cell RNA - A549 [nTPM]":"9.1","Cell RNA - AF22 [nTPM]":"12.3","Cell RNA - AN3-CA [nTPM]":"17.8","Cell RNA - ASC diff [nTPM]":"7.8","Cell RNA - ASC TERT1 [nTPM]":"9.7","Cell RNA - BEWO [nTPM]":"17.3","Cell RNA - BJ [nTPM]":"10.0","Cell RNA - BJ hTERT+ [nTPM]":"10.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.0","Cell RNA - CACO-2 [nTPM]":"10.7","Cell RNA - CAPAN-2 [nTPM]":"7.1","Cell RNA - Daudi [nTPM]":"29.7","Cell RNA - EFO-21 [nTPM]":"8.9","Cell RNA - fHDF\/TERT166 [nTPM]":"11.2","Cell RNA - GAMG [nTPM]":"13.5","Cell RNA - HaCaT [nTPM]":"15.5","Cell RNA - HAP1 [nTPM]":"18.6","Cell RNA - HBEC3-KT [nTPM]":"12.1","Cell RNA - HBF TERT88 [nTPM]":"16.4","Cell RNA - HDLM-2 [nTPM]":"14.2","Cell RNA - HEK 293 [nTPM]":"14.1","Cell RNA - HEL [nTPM]":"14.5","Cell RNA - HeLa [nTPM]":"9.7","Cell RNA - Hep G2 [nTPM]":"11.1","Cell RNA - HHSteC [nTPM]":"12.2","Cell RNA - HL-60 [nTPM]":"33.2","Cell RNA - HMC-1 [nTPM]":"12.5","Cell RNA - HSkMC [nTPM]":"9.6","Cell RNA - hTCEpi [nTPM]":"18.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.0","Cell RNA - hTERT-HME1 [nTPM]":"20.6","Cell RNA - hTERT-RPE1 [nTPM]":"9.9","Cell RNA - HUVEC TERT2 [nTPM]":"9.5","Cell RNA - JURKAT [nTPM]":"18.4","Cell RNA - K-562 [nTPM]":"26.8","Cell RNA - Karpas-707 [nTPM]":"9.4","Cell RNA - LHCN-M2 [nTPM]":"11.0","Cell RNA - MCF7 [nTPM]":"10.1","Cell RNA - MOLT-4 [nTPM]":"10.7","Cell RNA - NB-4 [nTPM]":"16.1","Cell RNA - NTERA-2 [nTPM]":"12.9","Cell RNA - OE19 [nTPM]":"15.6","Cell RNA - PC-3 [nTPM]":"10.5","Cell RNA - REH [nTPM]":"28.9","Cell RNA - RH-30 [nTPM]":"15.8","Cell RNA - RPMI-8226 [nTPM]":"7.5","Cell RNA - RPTEC TERT1 [nTPM]":"14.3","Cell RNA - RT4 [nTPM]":"10.2","Cell RNA - SCLC-21H [nTPM]":"10.7","Cell RNA - SH-SY5Y [nTPM]":"11.0","Cell RNA - SiHa [nTPM]":"8.0","Cell RNA - SK-BR-3 [nTPM]":"18.4","Cell RNA - SK-MEL-30 [nTPM]":"15.3","Cell RNA - SuSa [nTPM]":"10.7","Cell RNA - T-47d [nTPM]":"12.1","Cell RNA - THP-1 [nTPM]":"25.3","Cell RNA - TIME [nTPM]":"9.3","Cell RNA - U-138 MG [nTPM]":"9.2","Cell RNA - U-2 OS [nTPM]":"7.6","Cell RNA - U-2197 [nTPM]":"10.0","Cell RNA - U-251 MG [nTPM]":"15.7","Cell RNA - U-266\/70 [nTPM]":"5.4","Cell RNA - U-266\/84 [nTPM]":"8.3","Cell RNA - U-698 [nTPM]":"17.2","Cell RNA - U-87 MG [nTPM]":"12.6","Cell RNA - U-937 [nTPM]":"22.1","Cell RNA - WM-115 [nTPM]":"14.0","Blood RNA - basophil [nTPM]":"5.0","Blood RNA - classical monocyte [nTPM]":"6.4","Blood RNA - eosinophil [nTPM]":"1.0","Blood RNA - gdT-cell [nTPM]":"6.4","Blood RNA - intermediate monocyte [nTPM]":"9.6","Blood RNA - MAIT T-cell [nTPM]":"6.3","Blood RNA - memory B-cell [nTPM]":"86.4","Blood RNA - memory CD4 T-cell [nTPM]":"7.1","Blood RNA - memory CD8 T-cell [nTPM]":"5.6","Blood RNA - myeloid DC [nTPM]":"10.7","Blood RNA - naive B-cell [nTPM]":"71.0","Blood RNA - naive CD4 T-cell [nTPM]":"6.6","Blood RNA - naive CD8 T-cell [nTPM]":"6.4","Blood RNA - neutrophil [nTPM]":"1.6","Blood RNA - NK-cell [nTPM]":"7.0","Blood RNA - non-classical monocyte [nTPM]":"13.0","Blood RNA - plasmacytoid DC [nTPM]":"8.5","Blood RNA - T-reg [nTPM]":"8.5","Blood RNA - total PBMC [nTPM]":"5.7","Brain RNA - amygdala [nTPM]":"4.0","Brain RNA - basal ganglia [nTPM]":"5.2","Brain RNA - cerebellum [nTPM]":"4.7","Brain RNA - cerebral cortex [nTPM]":"5.0","Brain RNA - hippocampal formation [nTPM]":"4.1","Brain RNA - hypothalamus [nTPM]":"4.5","Brain RNA - medulla oblongata [nTPM]":"4.6","Brain RNA - midbrain [nTPM]":"4.5","Brain RNA - pons [nTPM]":"5.0","Brain RNA - spinal cord [nTPM]":"4.1","Brain RNA - thalamus [nTPM]":"4.5","Brain RNA - white matter [nTPM]":"7.4","Single Cell Type RNA - Adipocytes [nTPM]":"9.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.5","Single Cell Type RNA - Astrocytes [nTPM]":"20.2","Single Cell Type RNA - B-cells [nTPM]":"64.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"14.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"24.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"9.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"21.5","Single Cell Type RNA - dendritic cells [nTPM]":"12.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"15.4","Single Cell Type RNA - Early spermatids [nTPM]":"15.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"28.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.0","Single Cell Type RNA - Endothelial cells [nTPM]":"10.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.4","Single Cell Type RNA - Erythroid cells [nTPM]":"13.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"23.0","Single Cell Type RNA - Fibroblasts [nTPM]":"9.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.8","Single Cell Type RNA - granulocytes [nTPM]":"18.9","Single Cell Type RNA - Granulosa cells [nTPM]":"15.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.2","Single Cell Type RNA - Hepatocytes [nTPM]":"14.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.9","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.2","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"12.4","Single Cell Type RNA - Langerhans cells [nTPM]":"6.1","Single Cell Type RNA - Late spermatids [nTPM]":"8.4","Single Cell Type RNA - Leydig cells [nTPM]":"8.4","Single Cell Type RNA - Macrophages [nTPM]":"10.0","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"18.3","Single Cell Type RNA - Muller glia cells [nTPM]":"9.9","Single Cell Type RNA - NK-cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"26.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.2","Single Cell Type RNA - Paneth cells [nTPM]":"8.3","Single Cell Type RNA - Peritubular cells [nTPM]":"9.1","Single Cell Type RNA - Plasma cells [nTPM]":"13.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.0","Single Cell Type RNA - Spermatocytes [nTPM]":"25.6","Single Cell Type RNA - Spermatogonia [nTPM]":"14.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.3","Single Cell Type RNA - T-cells [nTPM]":"14.3","Single Cell Type RNA - Theca cells [nTPM]":"21.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.7","Single Cell Type RNA - Urothelial cells [nTPM]":"8.9"},{"Gene":"RAB27A","Gene synonym":["GS2","HsT18676","RAB27","RAM"],"Ensembl":"ENSG00000069974","Gene description":"RAB27A, member RAS oncogene family","Uniprot":["P51159"],"Chromosome":"15","Position":"55202966-55319113","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Exocytosis"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"stomach 1":"119.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"147.1","Intestinal goblet cells":"252.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"261.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HL-60":"208.7","K-562":"238.0","Karpas-707":"179.4","SK-MEL-30":"188.3","U-937":"185.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001333","CAB034046"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 27: Mucus-secreting cells - Mucin production","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB034046":"AB_2176724","HPA001333":"AB_1079730"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.56e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.75e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.67e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-1"},"Tissue RNA - adipose tissue [nTPM]":"17.5","Tissue RNA - adrenal gland [nTPM]":"27.8","Tissue RNA - amygdala [nTPM]":"3.5","Tissue RNA - appendix [nTPM]":"40.2","Tissue RNA - basal ganglia [nTPM]":"3.9","Tissue RNA - bone marrow [nTPM]":"100.2","Tissue RNA - breast [nTPM]":"13.9","Tissue RNA - cerebellum [nTPM]":"4.4","Tissue RNA - cerebral cortex [nTPM]":"4.4","Tissue RNA - cervix [nTPM]":"12.9","Tissue RNA - choroid plexus [nTPM]":"5.6","Tissue RNA - colon [nTPM]":"53.0","Tissue RNA - duodenum [nTPM]":"30.0","Tissue RNA - endometrium 1 [nTPM]":"12.8","Tissue RNA - epididymis [nTPM]":"5.0","Tissue RNA - esophagus [nTPM]":"20.6","Tissue RNA - fallopian tube [nTPM]":"12.3","Tissue RNA - gallbladder [nTPM]":"17.6","Tissue RNA - heart muscle [nTPM]":"7.7","Tissue RNA - hippocampal formation [nTPM]":"3.4","Tissue RNA - hypothalamus [nTPM]":"6.7","Tissue RNA - kidney [nTPM]":"19.2","Tissue RNA - liver [nTPM]":"43.6","Tissue RNA - lung [nTPM]":"42.4","Tissue RNA - lymph node [nTPM]":"46.0","Tissue RNA - medulla oblongata [nTPM]":"5.8","Tissue RNA - midbrain [nTPM]":"5.0","Tissue RNA - ovary [nTPM]":"8.0","Tissue RNA - pancreas [nTPM]":"29.2","Tissue RNA - parathyroid gland [nTPM]":"11.4","Tissue RNA - pituitary gland [nTPM]":"31.4","Tissue RNA - placenta [nTPM]":"17.6","Tissue RNA - pons [nTPM]":"5.9","Tissue RNA - prostate [nTPM]":"61.2","Tissue RNA - rectum [nTPM]":"66.1","Tissue RNA - retina [nTPM]":"4.2","Tissue RNA - salivary gland [nTPM]":"18.3","Tissue RNA - seminal vesicle [nTPM]":"11.8","Tissue RNA - skeletal muscle [nTPM]":"3.2","Tissue RNA - skin 1 [nTPM]":"12.8","Tissue RNA - small intestine [nTPM]":"40.9","Tissue RNA - smooth muscle [nTPM]":"25.8","Tissue RNA - spinal cord [nTPM]":"5.0","Tissue RNA - spleen [nTPM]":"30.8","Tissue RNA - stomach 1 [nTPM]":"119.9","Tissue RNA - testis [nTPM]":"10.0","Tissue RNA - thalamus [nTPM]":"5.9","Tissue RNA - thymus [nTPM]":"19.3","Tissue RNA - thyroid gland [nTPM]":"30.5","Tissue RNA - tongue [nTPM]":"7.0","Tissue RNA - tonsil [nTPM]":"46.2","Tissue RNA - urinary bladder [nTPM]":"37.5","Tissue RNA - vagina [nTPM]":"13.9","Tissue RNA - white matter [nTPM]":"5.7","Cell RNA - A-431 [nTPM]":"23.0","Cell RNA - A549 [nTPM]":"10.0","Cell RNA - AF22 [nTPM]":"9.7","Cell RNA - AN3-CA [nTPM]":"11.3","Cell RNA - ASC diff [nTPM]":"8.3","Cell RNA - ASC TERT1 [nTPM]":"38.8","Cell RNA - BEWO [nTPM]":"9.5","Cell RNA - BJ [nTPM]":"29.4","Cell RNA - BJ hTERT+ [nTPM]":"32.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"26.4","Cell RNA - CACO-2 [nTPM]":"7.0","Cell RNA - CAPAN-2 [nTPM]":"15.6","Cell RNA - Daudi [nTPM]":"0.9","Cell RNA - EFO-21 [nTPM]":"22.3","Cell RNA - fHDF\/TERT166 [nTPM]":"16.0","Cell RNA - GAMG [nTPM]":"38.9","Cell RNA - HaCaT [nTPM]":"16.0","Cell RNA - HAP1 [nTPM]":"15.7","Cell RNA - HBEC3-KT [nTPM]":"27.0","Cell RNA - HBF TERT88 [nTPM]":"18.3","Cell RNA - HDLM-2 [nTPM]":"84.9","Cell RNA - HEK 293 [nTPM]":"9.7","Cell RNA - HEL [nTPM]":"5.4","Cell RNA - HeLa [nTPM]":"37.6","Cell RNA - Hep G2 [nTPM]":"18.1","Cell RNA - HHSteC [nTPM]":"56.0","Cell RNA - HL-60 [nTPM]":"208.7","Cell RNA - HMC-1 [nTPM]":"26.5","Cell RNA - HSkMC [nTPM]":"34.3","Cell RNA - hTCEpi [nTPM]":"44.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"29.0","Cell RNA - hTERT-HME1 [nTPM]":"71.6","Cell RNA - hTERT-RPE1 [nTPM]":"80.7","Cell RNA - HUVEC TERT2 [nTPM]":"46.9","Cell RNA - JURKAT [nTPM]":"26.4","Cell RNA - K-562 [nTPM]":"238.0","Cell RNA - Karpas-707 [nTPM]":"179.4","Cell RNA - LHCN-M2 [nTPM]":"20.7","Cell RNA - MCF7 [nTPM]":"27.7","Cell RNA - MOLT-4 [nTPM]":"1.5","Cell RNA - NB-4 [nTPM]":"57.6","Cell RNA - NTERA-2 [nTPM]":"3.6","Cell RNA - OE19 [nTPM]":"38.9","Cell RNA - PC-3 [nTPM]":"14.7","Cell RNA - REH [nTPM]":"32.4","Cell RNA - RH-30 [nTPM]":"27.3","Cell RNA - RPMI-8226 [nTPM]":"50.3","Cell RNA - RPTEC TERT1 [nTPM]":"28.7","Cell RNA - RT4 [nTPM]":"17.7","Cell RNA - SCLC-21H [nTPM]":"14.9","Cell RNA - SH-SY5Y [nTPM]":"7.1","Cell RNA - SiHa [nTPM]":"31.4","Cell RNA - SK-BR-3 [nTPM]":"15.2","Cell RNA - SK-MEL-30 [nTPM]":"188.3","Cell RNA - SuSa [nTPM]":"24.3","Cell RNA - T-47d [nTPM]":"13.3","Cell RNA - THP-1 [nTPM]":"162.2","Cell RNA - TIME [nTPM]":"25.3","Cell RNA - U-138 MG [nTPM]":"52.5","Cell RNA - U-2 OS [nTPM]":"20.3","Cell RNA - U-2197 [nTPM]":"33.1","Cell RNA - U-251 MG [nTPM]":"33.6","Cell RNA - U-266\/70 [nTPM]":"72.0","Cell RNA - U-266\/84 [nTPM]":"88.2","Cell RNA - U-698 [nTPM]":"6.0","Cell RNA - U-87 MG [nTPM]":"70.2","Cell RNA - U-937 [nTPM]":"185.1","Cell RNA - WM-115 [nTPM]":"19.0","Blood RNA - basophil [nTPM]":"261.3","Blood RNA - classical monocyte [nTPM]":"72.4","Blood RNA - eosinophil [nTPM]":"99.8","Blood RNA - gdT-cell [nTPM]":"59.2","Blood RNA - intermediate monocyte [nTPM]":"30.1","Blood RNA - MAIT T-cell [nTPM]":"58.2","Blood RNA - memory B-cell [nTPM]":"8.0","Blood RNA - memory CD4 T-cell [nTPM]":"28.6","Blood RNA - memory CD8 T-cell [nTPM]":"61.9","Blood RNA - myeloid DC [nTPM]":"39.0","Blood RNA - naive B-cell [nTPM]":"13.4","Blood RNA - naive CD4 T-cell [nTPM]":"13.9","Blood RNA - naive CD8 T-cell [nTPM]":"37.4","Blood RNA - neutrophil [nTPM]":"114.9","Blood RNA - NK-cell [nTPM]":"34.1","Blood RNA - non-classical monocyte [nTPM]":"24.0","Blood RNA - plasmacytoid DC [nTPM]":"2.1","Blood RNA - T-reg [nTPM]":"36.2","Blood RNA - total PBMC [nTPM]":"48.9","Brain RNA - amygdala [nTPM]":"3.5","Brain RNA - basal ganglia [nTPM]":"3.9","Brain RNA - cerebellum [nTPM]":"4.4","Brain RNA - cerebral cortex [nTPM]":"4.4","Brain RNA - hippocampal formation [nTPM]":"3.4","Brain RNA - hypothalamus [nTPM]":"6.7","Brain RNA - medulla oblongata [nTPM]":"5.8","Brain RNA - midbrain [nTPM]":"5.0","Brain RNA - pons [nTPM]":"5.9","Brain RNA - spinal cord [nTPM]":"5.0","Brain RNA - thalamus [nTPM]":"5.9","Brain RNA - white matter [nTPM]":"5.7","Single Cell Type RNA - Adipocytes [nTPM]":"27.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"76.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"147.1","Single Cell Type RNA - Astrocytes [nTPM]":"12.7","Single Cell Type RNA - B-cells [nTPM]":"18.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"25.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"19.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"3.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"50.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.3","Single Cell Type RNA - dendritic cells [nTPM]":"81.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"24.6","Single Cell Type RNA - Early spermatids [nTPM]":"2.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.6","Single Cell Type RNA - Endothelial cells [nTPM]":"32.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"74.3","Single Cell Type RNA - Erythroid cells [nTPM]":"12.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"87.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.7","Single Cell Type RNA - Fibroblasts [nTPM]":"16.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"93.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.7","Single Cell Type RNA - granulocytes [nTPM]":"31.7","Single Cell Type RNA - Granulosa cells [nTPM]":"8.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"41.7","Single Cell Type RNA - Hepatocytes [nTPM]":"41.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"252.0","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"33.3","Single Cell Type RNA - Langerhans cells [nTPM]":"15.2","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"7.5","Single Cell Type RNA - Macrophages [nTPM]":"31.1","Single Cell Type RNA - Melanocytes [nTPM]":"71.2","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"71.9","Single Cell Type RNA - Muller glia cells [nTPM]":"2.4","Single Cell Type RNA - NK-cells [nTPM]":"104.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"62.9","Single Cell Type RNA - Paneth cells [nTPM]":"15.9","Single Cell Type RNA - Peritubular cells [nTPM]":"13.9","Single Cell Type RNA - Plasma cells [nTPM]":"38.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"32.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"31.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.4","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.8","Single Cell Type RNA - Spermatocytes [nTPM]":"9.3","Single Cell Type RNA - Spermatogonia [nTPM]":"4.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.5","Single Cell Type RNA - T-cells [nTPM]":"81.4","Single Cell Type RNA - Theca cells [nTPM]":"4.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.4","Single Cell Type RNA - Urothelial cells [nTPM]":"23.4"},{"Gene":"RAB7A","Gene synonym":["CMT2B","RAB7"],"Ensembl":"ENSG00000075785","Gene description":"RAB7A, member RAS oncogene family","Uniprot":["P51149"],"Chromosome":"3","Position":"128693669-128825942","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Autophagy","Host-virus interaction","Lipid degradation","Lipid metabolism","Protein transport","Transport"],"Molecular function":["Hydrolase"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006964","CAB037131"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Lysosomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5700000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 16: Pancreatic endocrine cells - Mixed function","Subcellular main location":["Lysosomes"],"Subcellular additional location":null,"Antibody RRID":{"CAB037131":"AB_477460","HPA006964":"AB_1856015"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.52e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.89e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.63e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-3"},"Tissue RNA - adipose tissue [nTPM]":"170.6","Tissue RNA - adrenal gland [nTPM]":"157.1","Tissue RNA - amygdala [nTPM]":"120.1","Tissue RNA - appendix [nTPM]":"101.4","Tissue RNA - basal ganglia [nTPM]":"132.2","Tissue RNA - bone marrow [nTPM]":"99.9","Tissue RNA - breast [nTPM]":"149.5","Tissue RNA - cerebellum [nTPM]":"133.4","Tissue RNA - cerebral cortex [nTPM]":"159.4","Tissue RNA - cervix [nTPM]":"138.3","Tissue RNA - choroid plexus [nTPM]":"123.7","Tissue RNA - colon [nTPM]":"128.9","Tissue RNA - duodenum [nTPM]":"108.3","Tissue RNA - endometrium 1 [nTPM]":"137.4","Tissue RNA - epididymis [nTPM]":"143.0","Tissue RNA - esophagus [nTPM]":"188.2","Tissue RNA - fallopian tube [nTPM]":"110.1","Tissue RNA - gallbladder [nTPM]":"109.7","Tissue RNA - heart muscle [nTPM]":"186.8","Tissue RNA - hippocampal formation [nTPM]":"128.9","Tissue RNA - hypothalamus [nTPM]":"138.4","Tissue RNA - kidney [nTPM]":"131.8","Tissue RNA - liver [nTPM]":"145.2","Tissue RNA - lung [nTPM]":"152.9","Tissue RNA - lymph node [nTPM]":"108.8","Tissue RNA - medulla oblongata [nTPM]":"138.8","Tissue RNA - midbrain [nTPM]":"142.0","Tissue RNA - ovary [nTPM]":"122.7","Tissue RNA - pancreas [nTPM]":"88.6","Tissue RNA - parathyroid gland [nTPM]":"155.9","Tissue RNA - pituitary gland [nTPM]":"101.5","Tissue RNA - placenta [nTPM]":"117.5","Tissue RNA - pons [nTPM]":"139.4","Tissue RNA - prostate [nTPM]":"101.3","Tissue RNA - rectum [nTPM]":"126.0","Tissue RNA - retina [nTPM]":"103.8","Tissue RNA - salivary gland [nTPM]":"133.3","Tissue RNA - seminal vesicle [nTPM]":"63.9","Tissue RNA - skeletal muscle [nTPM]":"332.4","Tissue RNA - skin 1 [nTPM]":"164.9","Tissue RNA - small intestine [nTPM]":"116.8","Tissue RNA - smooth muscle [nTPM]":"124.0","Tissue RNA - spinal cord [nTPM]":"135.9","Tissue RNA - spleen [nTPM]":"123.0","Tissue RNA - stomach 1 [nTPM]":"114.9","Tissue RNA - testis [nTPM]":"61.5","Tissue RNA - thalamus [nTPM]":"140.3","Tissue RNA - thymus [nTPM]":"124.6","Tissue RNA - thyroid gland [nTPM]":"122.5","Tissue RNA - tongue [nTPM]":"249.7","Tissue RNA - tonsil [nTPM]":"136.6","Tissue RNA - urinary bladder [nTPM]":"144.4","Tissue RNA - vagina [nTPM]":"143.4","Tissue RNA - white matter [nTPM]":"159.0","Cell RNA - A-431 [nTPM]":"280.2","Cell RNA - A549 [nTPM]":"95.5","Cell RNA - AF22 [nTPM]":"146.0","Cell RNA - AN3-CA [nTPM]":"78.3","Cell RNA - ASC diff [nTPM]":"300.6","Cell RNA - ASC TERT1 [nTPM]":"94.0","Cell RNA - BEWO [nTPM]":"126.0","Cell RNA - BJ [nTPM]":"252.8","Cell RNA - BJ hTERT+ [nTPM]":"183.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"164.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"158.8","Cell RNA - CACO-2 [nTPM]":"170.1","Cell RNA - CAPAN-2 [nTPM]":"179.2","Cell RNA - Daudi [nTPM]":"134.2","Cell RNA - EFO-21 [nTPM]":"163.2","Cell RNA - fHDF\/TERT166 [nTPM]":"236.2","Cell RNA - GAMG [nTPM]":"289.9","Cell RNA - HaCaT [nTPM]":"163.4","Cell RNA - HAP1 [nTPM]":"175.2","Cell RNA - HBEC3-KT [nTPM]":"248.6","Cell RNA - HBF TERT88 [nTPM]":"99.2","Cell RNA - HDLM-2 [nTPM]":"149.4","Cell RNA - HEK 293 [nTPM]":"111.7","Cell RNA - HEL [nTPM]":"294.3","Cell RNA - HeLa [nTPM]":"83.6","Cell RNA - Hep G2 [nTPM]":"165.8","Cell RNA - HHSteC [nTPM]":"303.0","Cell RNA - HL-60 [nTPM]":"269.4","Cell RNA - HMC-1 [nTPM]":"182.5","Cell RNA - HSkMC [nTPM]":"243.7","Cell RNA - hTCEpi [nTPM]":"104.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"176.7","Cell RNA - hTERT-HME1 [nTPM]":"204.4","Cell RNA - hTERT-RPE1 [nTPM]":"220.7","Cell RNA - HUVEC TERT2 [nTPM]":"89.2","Cell RNA - JURKAT [nTPM]":"114.4","Cell RNA - K-562 [nTPM]":"143.4","Cell RNA - Karpas-707 [nTPM]":"148.0","Cell RNA - LHCN-M2 [nTPM]":"108.1","Cell RNA - MCF7 [nTPM]":"213.1","Cell RNA - MOLT-4 [nTPM]":"176.8","Cell RNA - NB-4 [nTPM]":"294.6","Cell RNA - NTERA-2 [nTPM]":"121.4","Cell RNA - OE19 [nTPM]":"294.8","Cell RNA - PC-3 [nTPM]":"144.8","Cell RNA - REH [nTPM]":"140.2","Cell RNA - RH-30 [nTPM]":"130.7","Cell RNA - RPMI-8226 [nTPM]":"170.4","Cell RNA - RPTEC TERT1 [nTPM]":"85.7","Cell RNA - RT4 [nTPM]":"205.4","Cell RNA - SCLC-21H [nTPM]":"105.8","Cell RNA - SH-SY5Y [nTPM]":"138.5","Cell RNA - SiHa [nTPM]":"142.1","Cell RNA - SK-BR-3 [nTPM]":"194.7","Cell RNA - SK-MEL-30 [nTPM]":"405.4","Cell RNA - SuSa [nTPM]":"174.9","Cell RNA - T-47d [nTPM]":"180.3","Cell RNA - THP-1 [nTPM]":"254.8","Cell RNA - TIME [nTPM]":"202.9","Cell RNA - U-138 MG [nTPM]":"192.7","Cell RNA - U-2 OS [nTPM]":"98.0","Cell RNA - U-2197 [nTPM]":"325.7","Cell RNA - U-251 MG [nTPM]":"125.9","Cell RNA - U-266\/70 [nTPM]":"184.4","Cell RNA - U-266\/84 [nTPM]":"187.0","Cell RNA - U-698 [nTPM]":"192.0","Cell RNA - U-87 MG [nTPM]":"312.7","Cell RNA - U-937 [nTPM]":"212.1","Cell RNA - WM-115 [nTPM]":"235.5","Blood RNA - basophil [nTPM]":"194.9","Blood RNA - classical monocyte [nTPM]":"176.8","Blood RNA - eosinophil [nTPM]":"213.6","Blood RNA - gdT-cell [nTPM]":"92.1","Blood RNA - intermediate monocyte [nTPM]":"192.3","Blood RNA - MAIT T-cell [nTPM]":"92.3","Blood RNA - memory B-cell [nTPM]":"93.2","Blood RNA - memory CD4 T-cell [nTPM]":"97.4","Blood RNA - memory CD8 T-cell [nTPM]":"94.5","Blood RNA - myeloid DC [nTPM]":"200.0","Blood RNA - naive B-cell [nTPM]":"85.8","Blood RNA - naive CD4 T-cell [nTPM]":"94.8","Blood RNA - naive CD8 T-cell [nTPM]":"93.6","Blood RNA - neutrophil [nTPM]":"374.2","Blood RNA - NK-cell [nTPM]":"128.8","Blood RNA - non-classical monocyte [nTPM]":"204.0","Blood RNA - plasmacytoid DC [nTPM]":"81.8","Blood RNA - T-reg [nTPM]":"120.7","Blood RNA - total PBMC [nTPM]":"201.3","Brain RNA - amygdala [nTPM]":"120.1","Brain RNA - basal ganglia [nTPM]":"132.2","Brain RNA - cerebellum [nTPM]":"133.4","Brain RNA - cerebral cortex [nTPM]":"159.4","Brain RNA - hippocampal formation [nTPM]":"128.9","Brain RNA - hypothalamus [nTPM]":"138.4","Brain RNA - medulla oblongata [nTPM]":"138.8","Brain RNA - midbrain [nTPM]":"142.0","Brain RNA - pons [nTPM]":"139.4","Brain RNA - spinal cord [nTPM]":"135.9","Brain RNA - thalamus [nTPM]":"140.3","Brain RNA - white matter [nTPM]":"159.0","Single Cell Type RNA - Adipocytes [nTPM]":"154.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"89.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"81.8","Single Cell Type RNA - Astrocytes [nTPM]":"66.9","Single Cell Type RNA - B-cells [nTPM]":"109.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"296.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"331.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"218.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"104.7","Single Cell Type RNA - Bipolar cells [nTPM]":"66.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"112.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"73.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"110.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"90.1","Single Cell Type RNA - Club cells [nTPM]":"129.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"132.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"230.0","Single Cell Type RNA - dendritic cells [nTPM]":"92.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"222.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"240.7","Single Cell Type RNA - Ductal cells [nTPM]":"259.6","Single Cell Type RNA - Early spermatids [nTPM]":"11.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"90.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"90.8","Single Cell Type RNA - Endothelial cells [nTPM]":"165.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"96.9","Single Cell Type RNA - Erythroid cells [nTPM]":"111.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"83.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"198.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"283.4","Single Cell Type RNA - Fibroblasts [nTPM]":"172.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"79.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"142.4","Single Cell Type RNA - granulocytes [nTPM]":"146.2","Single Cell Type RNA - Granulosa cells [nTPM]":"46.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"142.8","Single Cell Type RNA - Hepatocytes [nTPM]":"127.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"403.9","Single Cell Type RNA - Horizontal cells [nTPM]":"74.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"82.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"122.8","Single Cell Type RNA - Ionocytes [nTPM]":"219.7","Single Cell Type RNA - Kupffer cells [nTPM]":"208.6","Single Cell Type RNA - Langerhans cells [nTPM]":"379.9","Single Cell Type RNA - Late spermatids [nTPM]":"19.6","Single Cell Type RNA - Leydig cells [nTPM]":"133.6","Single Cell Type RNA - Macrophages [nTPM]":"242.8","Single Cell Type RNA - Melanocytes [nTPM]":"339.7","Single Cell Type RNA - Microglial cells [nTPM]":"99.3","Single Cell Type RNA - monocytes [nTPM]":"220.9","Single Cell Type RNA - Muller glia cells [nTPM]":"154.6","Single Cell Type RNA - NK-cells [nTPM]":"121.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"80.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"111.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"303.7","Single Cell Type RNA - Paneth cells [nTPM]":"185.0","Single Cell Type RNA - Peritubular cells [nTPM]":"157.2","Single Cell Type RNA - Plasma cells [nTPM]":"79.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"279.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"172.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"332.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"118.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"37.6","Single Cell Type RNA - Sertoli cells [nTPM]":"138.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"107.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"160.5","Single Cell Type RNA - Spermatocytes [nTPM]":"116.4","Single Cell Type RNA - Spermatogonia [nTPM]":"100.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"122.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"308.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"497.9","Single Cell Type RNA - T-cells [nTPM]":"107.7","Single Cell Type RNA - Theca cells [nTPM]":"109.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"103.5","Single Cell Type RNA - Urothelial cells [nTPM]":"324.6"},{"Gene":"RAC1","Gene synonym":["p21-Rac1","Rac-1","TC-25"],"Ensembl":"ENSG00000136238","Gene description":"Rac family small GTPase 1","Uniprot":["P63000"],"Chromosome":"7","Position":"6374527-6403967","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Urothelial cells":"1980.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB035994","HPA047820"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3900000","Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"CAB035994":null,"HPA047820":"AB_2680167"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.74e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.59e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.57e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.11e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-3"},"Tissue RNA - adipose tissue [nTPM]":"157.4","Tissue RNA - adrenal gland [nTPM]":"108.0","Tissue RNA - amygdala [nTPM]":"237.0","Tissue RNA - appendix [nTPM]":"96.8","Tissue RNA - basal ganglia [nTPM]":"250.4","Tissue RNA - bone marrow [nTPM]":"94.5","Tissue RNA - breast [nTPM]":"146.4","Tissue RNA - cerebellum [nTPM]":"242.4","Tissue RNA - cerebral cortex [nTPM]":"290.7","Tissue RNA - cervix [nTPM]":"154.8","Tissue RNA - choroid plexus [nTPM]":"206.5","Tissue RNA - colon [nTPM]":"190.5","Tissue RNA - duodenum [nTPM]":"167.4","Tissue RNA - endometrium 1 [nTPM]":"150.7","Tissue RNA - epididymis [nTPM]":"149.9","Tissue RNA - esophagus [nTPM]":"316.9","Tissue RNA - fallopian tube [nTPM]":"145.1","Tissue RNA - gallbladder [nTPM]":"125.9","Tissue RNA - heart muscle [nTPM]":"129.4","Tissue RNA - hippocampal formation [nTPM]":"240.2","Tissue RNA - hypothalamus [nTPM]":"240.6","Tissue RNA - kidney [nTPM]":"150.5","Tissue RNA - liver [nTPM]":"136.2","Tissue RNA - lung [nTPM]":"147.5","Tissue RNA - lymph node [nTPM]":"96.4","Tissue RNA - medulla oblongata [nTPM]":"249.4","Tissue RNA - midbrain [nTPM]":"244.8","Tissue RNA - ovary [nTPM]":"135.8","Tissue RNA - pancreas [nTPM]":"92.2","Tissue RNA - parathyroid gland [nTPM]":"151.1","Tissue RNA - pituitary gland [nTPM]":"77.5","Tissue RNA - placenta [nTPM]":"180.2","Tissue RNA - pons [nTPM]":"249.2","Tissue RNA - prostate [nTPM]":"122.8","Tissue RNA - rectum [nTPM]":"199.6","Tissue RNA - retina [nTPM]":"52.2","Tissue RNA - salivary gland [nTPM]":"137.9","Tissue RNA - seminal vesicle [nTPM]":"145.0","Tissue RNA - skeletal muscle [nTPM]":"179.5","Tissue RNA - skin 1 [nTPM]":"189.2","Tissue RNA - small intestine [nTPM]":"161.9","Tissue RNA - smooth muscle [nTPM]":"179.3","Tissue RNA - spinal cord [nTPM]":"260.2","Tissue RNA - spleen [nTPM]":"96.6","Tissue RNA - stomach 1 [nTPM]":"160.6","Tissue RNA - testis [nTPM]":"51.6","Tissue RNA - thalamus [nTPM]":"241.1","Tissue RNA - thymus [nTPM]":"115.3","Tissue RNA - thyroid gland [nTPM]":"127.2","Tissue RNA - tongue [nTPM]":"141.1","Tissue RNA - tonsil [nTPM]":"169.6","Tissue RNA - urinary bladder [nTPM]":"205.3","Tissue RNA - vagina [nTPM]":"188.6","Tissue RNA - white matter [nTPM]":"262.9","Cell RNA - A-431 [nTPM]":"519.9","Cell RNA - A549 [nTPM]":"230.9","Cell RNA - AF22 [nTPM]":"233.0","Cell RNA - AN3-CA [nTPM]":"255.1","Cell RNA - ASC diff [nTPM]":"270.1","Cell RNA - ASC TERT1 [nTPM]":"341.8","Cell RNA - BEWO [nTPM]":"138.6","Cell RNA - BJ [nTPM]":"284.9","Cell RNA - BJ hTERT+ [nTPM]":"348.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"371.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"375.8","Cell RNA - CACO-2 [nTPM]":"227.3","Cell RNA - CAPAN-2 [nTPM]":"474.8","Cell RNA - Daudi [nTPM]":"145.5","Cell RNA - EFO-21 [nTPM]":"179.7","Cell RNA - fHDF\/TERT166 [nTPM]":"400.9","Cell RNA - GAMG [nTPM]":"384.2","Cell RNA - HaCaT [nTPM]":"359.4","Cell RNA - HAP1 [nTPM]":"251.5","Cell RNA - HBEC3-KT [nTPM]":"345.9","Cell RNA - HBF TERT88 [nTPM]":"471.9","Cell RNA - HDLM-2 [nTPM]":"68.3","Cell RNA - HEK 293 [nTPM]":"207.8","Cell RNA - HEL [nTPM]":"146.6","Cell RNA - HeLa [nTPM]":"171.7","Cell RNA - Hep G2 [nTPM]":"166.5","Cell RNA - HHSteC [nTPM]":"323.7","Cell RNA - HL-60 [nTPM]":"134.0","Cell RNA - HMC-1 [nTPM]":"114.6","Cell RNA - HSkMC [nTPM]":"229.7","Cell RNA - hTCEpi [nTPM]":"302.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"268.4","Cell RNA - hTERT-HME1 [nTPM]":"297.6","Cell RNA - hTERT-RPE1 [nTPM]":"281.7","Cell RNA - HUVEC TERT2 [nTPM]":"333.4","Cell RNA - JURKAT [nTPM]":"141.3","Cell RNA - K-562 [nTPM]":"266.2","Cell RNA - Karpas-707 [nTPM]":"111.7","Cell RNA - LHCN-M2 [nTPM]":"406.4","Cell RNA - MCF7 [nTPM]":"377.3","Cell RNA - MOLT-4 [nTPM]":"74.0","Cell RNA - NB-4 [nTPM]":"312.4","Cell RNA - NTERA-2 [nTPM]":"419.1","Cell RNA - OE19 [nTPM]":"261.9","Cell RNA - PC-3 [nTPM]":"272.3","Cell RNA - REH [nTPM]":"129.2","Cell RNA - RH-30 [nTPM]":"236.9","Cell RNA - RPMI-8226 [nTPM]":"214.6","Cell RNA - RPTEC TERT1 [nTPM]":"481.7","Cell RNA - RT4 [nTPM]":"322.7","Cell RNA - SCLC-21H [nTPM]":"175.8","Cell RNA - SH-SY5Y [nTPM]":"295.9","Cell RNA - SiHa [nTPM]":"201.7","Cell RNA - SK-BR-3 [nTPM]":"726.1","Cell RNA - SK-MEL-30 [nTPM]":"241.4","Cell RNA - SuSa [nTPM]":"264.7","Cell RNA - T-47d [nTPM]":"409.6","Cell RNA - THP-1 [nTPM]":"396.3","Cell RNA - TIME [nTPM]":"341.8","Cell RNA - U-138 MG [nTPM]":"242.4","Cell RNA - U-2 OS [nTPM]":"364.3","Cell RNA - U-2197 [nTPM]":"300.7","Cell RNA - U-251 MG [nTPM]":"334.5","Cell RNA - U-266\/70 [nTPM]":"84.1","Cell RNA - U-266\/84 [nTPM]":"99.5","Cell RNA - U-698 [nTPM]":"135.4","Cell RNA - U-87 MG [nTPM]":"223.9","Cell RNA - U-937 [nTPM]":"250.9","Cell RNA - WM-115 [nTPM]":"470.6","Blood RNA - basophil [nTPM]":"31.0","Blood RNA - classical monocyte [nTPM]":"117.3","Blood RNA - eosinophil [nTPM]":"63.0","Blood RNA - gdT-cell [nTPM]":"23.8","Blood RNA - intermediate monocyte [nTPM]":"83.0","Blood RNA - MAIT T-cell [nTPM]":"15.1","Blood RNA - memory B-cell [nTPM]":"46.8","Blood RNA - memory CD4 T-cell [nTPM]":"26.8","Blood RNA - memory CD8 T-cell [nTPM]":"30.9","Blood RNA - myeloid DC [nTPM]":"112.8","Blood RNA - naive B-cell [nTPM]":"49.9","Blood RNA - naive CD4 T-cell [nTPM]":"33.0","Blood RNA - naive CD8 T-cell [nTPM]":"21.8","Blood RNA - neutrophil [nTPM]":"168.6","Blood RNA - NK-cell [nTPM]":"26.1","Blood RNA - non-classical monocyte [nTPM]":"83.5","Blood RNA - plasmacytoid DC [nTPM]":"64.5","Blood RNA - T-reg [nTPM]":"46.1","Blood RNA - total PBMC [nTPM]":"47.0","Brain RNA - amygdala [nTPM]":"237.0","Brain RNA - basal ganglia [nTPM]":"250.4","Brain RNA - cerebellum [nTPM]":"242.4","Brain RNA - cerebral cortex [nTPM]":"290.7","Brain RNA - hippocampal formation [nTPM]":"240.2","Brain RNA - hypothalamus [nTPM]":"240.6","Brain RNA - medulla oblongata [nTPM]":"249.4","Brain RNA - midbrain [nTPM]":"244.8","Brain RNA - pons [nTPM]":"249.2","Brain RNA - spinal cord [nTPM]":"260.2","Brain RNA - thalamus [nTPM]":"241.1","Brain RNA - white matter [nTPM]":"262.9","Single Cell Type RNA - Adipocytes [nTPM]":"755.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"147.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"123.6","Single Cell Type RNA - Astrocytes [nTPM]":"28.7","Single Cell Type RNA - B-cells [nTPM]":"155.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"934.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"981.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"232.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"429.2","Single Cell Type RNA - Bipolar cells [nTPM]":"90.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"485.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"593.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"200.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"484.7","Single Cell Type RNA - Club cells [nTPM]":"164.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"356.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"802.8","Single Cell Type RNA - dendritic cells [nTPM]":"224.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"920.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"536.1","Single Cell Type RNA - Ductal cells [nTPM]":"183.5","Single Cell Type RNA - Early spermatids [nTPM]":"77.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"388.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"362.9","Single Cell Type RNA - Endothelial cells [nTPM]":"641.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"336.7","Single Cell Type RNA - Erythroid cells [nTPM]":"313.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"43.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"174.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1064.1","Single Cell Type RNA - Fibroblasts [nTPM]":"415.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"305.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"422.8","Single Cell Type RNA - granulocytes [nTPM]":"130.9","Single Cell Type RNA - Granulosa cells [nTPM]":"325.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"580.8","Single Cell Type RNA - Hepatocytes [nTPM]":"367.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"832.0","Single Cell Type RNA - Horizontal cells [nTPM]":"146.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"35.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"632.9","Single Cell Type RNA - Ionocytes [nTPM]":"179.0","Single Cell Type RNA - Kupffer cells [nTPM]":"811.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1066.7","Single Cell Type RNA - Late spermatids [nTPM]":"58.8","Single Cell Type RNA - Leydig cells [nTPM]":"476.3","Single Cell Type RNA - Macrophages [nTPM]":"705.7","Single Cell Type RNA - Melanocytes [nTPM]":"458.9","Single Cell Type RNA - Microglial cells [nTPM]":"66.5","Single Cell Type RNA - monocytes [nTPM]":"607.2","Single Cell Type RNA - Muller glia cells [nTPM]":"341.1","Single Cell Type RNA - NK-cells [nTPM]":"191.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"23.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"56.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"299.1","Single Cell Type RNA - Paneth cells [nTPM]":"754.4","Single Cell Type RNA - Peritubular cells [nTPM]":"472.8","Single Cell Type RNA - Plasma cells [nTPM]":"212.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1495.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"816.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"832.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"214.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"64.2","Single Cell Type RNA - Sertoli cells [nTPM]":"479.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"346.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"466.6","Single Cell Type RNA - Spermatocytes [nTPM]":"216.6","Single Cell Type RNA - Spermatogonia [nTPM]":"373.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"774.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1148.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"845.4","Single Cell Type RNA - T-cells [nTPM]":"180.0","Single Cell Type RNA - Theca cells [nTPM]":"353.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"573.7","Single Cell Type RNA - Urothelial cells [nTPM]":"1980.7"},{"Gene":"RAC3","Gene synonym":[],"Ensembl":"ENSG00000169750","Gene description":"Rac family small GTPase 3","Uniprot":["P60763"],"Chromosome":"17","Position":"82031678-82034204","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast myoepithelial cells":"45.0","Extravillous trophoblasts":"152.1","Spermatogonia":"58.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"230.8","HEK 293":"274.7","NB-4":"156.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047820"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047820":"AB_2680167"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.21e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.69e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-3"},"Tissue RNA - adipose tissue [nTPM]":"12.3","Tissue RNA - adrenal gland [nTPM]":"5.0","Tissue RNA - amygdala [nTPM]":"22.8","Tissue RNA - appendix [nTPM]":"1.8","Tissue RNA - basal ganglia [nTPM]":"20.8","Tissue RNA - bone marrow [nTPM]":"7.7","Tissue RNA - breast [nTPM]":"13.7","Tissue RNA - cerebellum [nTPM]":"26.3","Tissue RNA - cerebral cortex [nTPM]":"29.5","Tissue RNA - cervix [nTPM]":"5.3","Tissue RNA - choroid plexus [nTPM]":"9.3","Tissue RNA - colon [nTPM]":"4.8","Tissue RNA - duodenum [nTPM]":"3.4","Tissue RNA - endometrium 1 [nTPM]":"2.8","Tissue RNA - epididymis [nTPM]":"7.3","Tissue RNA - esophagus [nTPM]":"10.9","Tissue RNA - fallopian tube [nTPM]":"3.8","Tissue RNA - gallbladder [nTPM]":"3.0","Tissue RNA - heart muscle [nTPM]":"3.0","Tissue RNA - hippocampal formation [nTPM]":"19.7","Tissue RNA - hypothalamus [nTPM]":"24.5","Tissue RNA - kidney [nTPM]":"9.4","Tissue RNA - liver [nTPM]":"20.7","Tissue RNA - lung [nTPM]":"4.0","Tissue RNA - lymph node [nTPM]":"1.7","Tissue RNA - medulla oblongata [nTPM]":"23.3","Tissue RNA - midbrain [nTPM]":"22.3","Tissue RNA - ovary [nTPM]":"4.8","Tissue RNA - pancreas [nTPM]":"4.7","Tissue RNA - parathyroid gland [nTPM]":"9.3","Tissue RNA - pituitary gland [nTPM]":"22.8","Tissue RNA - placenta [nTPM]":"5.6","Tissue RNA - pons [nTPM]":"27.0","Tissue RNA - prostate [nTPM]":"11.1","Tissue RNA - rectum [nTPM]":"1.4","Tissue RNA - retina [nTPM]":"2.8","Tissue RNA - salivary gland [nTPM]":"18.1","Tissue RNA - seminal vesicle [nTPM]":"4.2","Tissue RNA - skeletal muscle [nTPM]":"0.8","Tissue RNA - skin 1 [nTPM]":"12.4","Tissue RNA - small intestine [nTPM]":"3.7","Tissue RNA - smooth muscle [nTPM]":"1.3","Tissue RNA - spinal cord [nTPM]":"15.3","Tissue RNA - spleen [nTPM]":"1.9","Tissue RNA - stomach 1 [nTPM]":"11.8","Tissue RNA - testis [nTPM]":"28.1","Tissue RNA - thalamus [nTPM]":"26.5","Tissue RNA - thymus [nTPM]":"2.2","Tissue RNA - thyroid gland [nTPM]":"9.8","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"1.5","Tissue RNA - urinary bladder [nTPM]":"3.1","Tissue RNA - vagina [nTPM]":"7.6","Tissue RNA - white matter [nTPM]":"20.6","Cell RNA - A-431 [nTPM]":"11.1","Cell RNA - A549 [nTPM]":"15.1","Cell RNA - AF22 [nTPM]":"45.6","Cell RNA - AN3-CA [nTPM]":"63.1","Cell RNA - ASC diff [nTPM]":"9.7","Cell RNA - ASC TERT1 [nTPM]":"18.2","Cell RNA - BEWO [nTPM]":"50.5","Cell RNA - BJ [nTPM]":"7.8","Cell RNA - BJ hTERT+ [nTPM]":"7.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"26.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"22.3","Cell RNA - CACO-2 [nTPM]":"230.8","Cell RNA - CAPAN-2 [nTPM]":"21.4","Cell RNA - Daudi [nTPM]":"5.8","Cell RNA - EFO-21 [nTPM]":"11.5","Cell RNA - fHDF\/TERT166 [nTPM]":"4.8","Cell RNA - GAMG [nTPM]":"1.7","Cell RNA - HaCaT [nTPM]":"15.6","Cell RNA - HAP1 [nTPM]":"43.0","Cell RNA - HBEC3-KT [nTPM]":"17.8","Cell RNA - HBF TERT88 [nTPM]":"4.1","Cell RNA - HDLM-2 [nTPM]":"3.6","Cell RNA - HEK 293 [nTPM]":"274.7","Cell RNA - HEL [nTPM]":"64.6","Cell RNA - HeLa [nTPM]":"20.2","Cell RNA - Hep G2 [nTPM]":"16.7","Cell RNA - HHSteC [nTPM]":"47.0","Cell RNA - HL-60 [nTPM]":"28.0","Cell RNA - HMC-1 [nTPM]":"12.2","Cell RNA - HSkMC [nTPM]":"27.5","Cell RNA - hTCEpi [nTPM]":"13.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.5","Cell RNA - hTERT-HME1 [nTPM]":"12.0","Cell RNA - hTERT-RPE1 [nTPM]":"19.5","Cell RNA - HUVEC TERT2 [nTPM]":"60.3","Cell RNA - JURKAT [nTPM]":"33.8","Cell RNA - K-562 [nTPM]":"103.1","Cell RNA - Karpas-707 [nTPM]":"30.2","Cell RNA - LHCN-M2 [nTPM]":"10.8","Cell RNA - MCF7 [nTPM]":"35.6","Cell RNA - MOLT-4 [nTPM]":"7.3","Cell RNA - NB-4 [nTPM]":"156.4","Cell RNA - NTERA-2 [nTPM]":"61.4","Cell RNA - OE19 [nTPM]":"39.2","Cell RNA - PC-3 [nTPM]":"27.6","Cell RNA - REH [nTPM]":"47.6","Cell RNA - RH-30 [nTPM]":"4.5","Cell RNA - RPMI-8226 [nTPM]":"27.7","Cell RNA - RPTEC TERT1 [nTPM]":"20.0","Cell RNA - RT4 [nTPM]":"5.4","Cell RNA - SCLC-21H [nTPM]":"109.8","Cell RNA - SH-SY5Y [nTPM]":"111.5","Cell RNA - SiHa [nTPM]":"4.1","Cell RNA - SK-BR-3 [nTPM]":"57.2","Cell RNA - SK-MEL-30 [nTPM]":"55.7","Cell RNA - SuSa [nTPM]":"16.1","Cell RNA - T-47d [nTPM]":"58.6","Cell RNA - THP-1 [nTPM]":"40.7","Cell RNA - TIME [nTPM]":"21.6","Cell RNA - U-138 MG [nTPM]":"10.8","Cell RNA - U-2 OS [nTPM]":"9.8","Cell RNA - U-2197 [nTPM]":"5.5","Cell RNA - U-251 MG [nTPM]":"12.1","Cell RNA - U-266\/70 [nTPM]":"14.6","Cell RNA - U-266\/84 [nTPM]":"9.9","Cell RNA - U-698 [nTPM]":"4.4","Cell RNA - U-87 MG [nTPM]":"6.6","Cell RNA - U-937 [nTPM]":"17.3","Cell RNA - WM-115 [nTPM]":"18.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"22.8","Brain RNA - basal ganglia [nTPM]":"20.8","Brain RNA - cerebellum [nTPM]":"26.3","Brain RNA - cerebral cortex [nTPM]":"29.5","Brain RNA - hippocampal formation [nTPM]":"19.7","Brain RNA - hypothalamus [nTPM]":"24.5","Brain RNA - medulla oblongata [nTPM]":"23.3","Brain RNA - midbrain [nTPM]":"22.3","Brain RNA - pons [nTPM]":"27.0","Brain RNA - spinal cord [nTPM]":"15.3","Brain RNA - thalamus [nTPM]":"26.5","Brain RNA - white matter [nTPM]":"20.6","Single Cell Type RNA - Adipocytes [nTPM]":"1.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.3","Single Cell Type RNA - B-cells [nTPM]":"0.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.9","Single Cell Type RNA - Bipolar cells [nTPM]":"5.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"36.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"45.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"3.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"30.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"9.8","Single Cell Type RNA - Early spermatids [nTPM]":"19.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.4","Single Cell Type RNA - Endothelial cells [nTPM]":"2.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"6.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"152.1","Single Cell Type RNA - Fibroblasts [nTPM]":"10.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.6","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"17.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"11.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.7","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.1","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"2.6","Single Cell Type RNA - Late spermatids [nTPM]":"16.6","Single Cell Type RNA - Leydig cells [nTPM]":"5.6","Single Cell Type RNA - Macrophages [nTPM]":"0.9","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"2.0","Single Cell Type RNA - Muller glia cells [nTPM]":"6.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.5","Single Cell Type RNA - Paneth cells [nTPM]":"2.4","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"2.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"26.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.3","Single Cell Type RNA - Spermatocytes [nTPM]":"2.2","Single Cell Type RNA - Spermatogonia [nTPM]":"58.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.1","Single Cell Type RNA - T-cells [nTPM]":"3.1","Single Cell Type RNA - Theca cells [nTPM]":"8.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.2","Single Cell Type RNA - Urothelial cells [nTPM]":"8.4"},{"Gene":"RAG1","Gene synonym":["MGC43321","RNF74"],"Ensembl":"ENSG00000166349","Gene description":"Recombination activating 1","Uniprot":["P15918"],"Chromosome":"11","Position":"36510709-36593156","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA recombination","Ubl conjugation pathway"],"Molecular function":["Chromatin regulator","DNA-binding","Endonuclease","Hydrolase","Multifunctional enzyme","Nuclease","Transferase"],"Disease involvement":["Disease variant","SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"92","RNA tissue specific nTPM":{"lymphoid tissue":"395.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"3.9","Hepatic stellate cells":"8.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"MOLT-4":"283.5","REH":"266.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043939"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA043939":"AB_2732512"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"4.3","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.8","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.8","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"1.3","Tissue RNA - liver [nTPM]":"0.8","Tissue RNA - lung [nTPM]":"0.6","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.6","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"1.0","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"2.6","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"395.0","Tissue RNA - thyroid gland [nTPM]":"2.4","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"0.6","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.6","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.5","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.5","Cell RNA - JURKAT [nTPM]":"54.0","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"283.5","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"2.2","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"266.4","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.9","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.7","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"1.2","Cell RNA - T-47d [nTPM]":"1.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"1.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"2.3","Cell RNA - U-266\/84 [nTPM]":"1.9","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"1.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"2.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"1.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.2","Single Cell Type RNA - Hepatocytes [nTPM]":"2.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"1.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"1.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"RANBP2","Gene synonym":["ADANE","ANE1","NUP358"],"Ensembl":"ENSG00000153201","Gene description":"RAN binding protein 2","Uniprot":["P49792"],"Chromosome":"2","Position":"108719482-108785809","Protein class":["Cancer-related genes","Disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["mRNA transport","Protein transport","Translocation","Transport","Ubl conjugation pathway"],"Molecular function":["RNA-binding","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018437","HPA023960","CAB034063","HPA049497","HPA051675","HPA067564"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"160000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 65: Plasmacytoid DCs - Unknown function","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":["Nucleoplasm","Vesicles"],"Antibody RRID":{"CAB034063":"AB_2176784","HPA018437":"AB_2620151","HPA023960":"AB_2671385","HPA049497":"AB_2680794","HPA051675":"AB_2681570","HPA067564":"AB_2685862"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Tissue RNA - adipose tissue [nTPM]":"20.3","Tissue RNA - adrenal gland [nTPM]":"24.3","Tissue RNA - amygdala [nTPM]":"8.6","Tissue RNA - appendix [nTPM]":"16.3","Tissue RNA - basal ganglia [nTPM]":"11.6","Tissue RNA - bone marrow [nTPM]":"42.1","Tissue RNA - breast [nTPM]":"19.7","Tissue RNA - cerebellum [nTPM]":"14.4","Tissue RNA - cerebral cortex [nTPM]":"17.1","Tissue RNA - cervix [nTPM]":"18.1","Tissue RNA - choroid plexus [nTPM]":"20.3","Tissue RNA - colon [nTPM]":"15.6","Tissue RNA - duodenum [nTPM]":"13.4","Tissue RNA - endometrium 1 [nTPM]":"17.7","Tissue RNA - epididymis [nTPM]":"20.5","Tissue RNA - esophagus [nTPM]":"14.3","Tissue RNA - fallopian tube [nTPM]":"14.6","Tissue RNA - gallbladder [nTPM]":"13.7","Tissue RNA - heart muscle [nTPM]":"14.9","Tissue RNA - hippocampal formation [nTPM]":"11.8","Tissue RNA - hypothalamus [nTPM]":"9.4","Tissue RNA - kidney [nTPM]":"18.1","Tissue RNA - liver [nTPM]":"17.4","Tissue RNA - lung [nTPM]":"14.0","Tissue RNA - lymph node [nTPM]":"18.6","Tissue RNA - medulla oblongata [nTPM]":"9.2","Tissue RNA - midbrain [nTPM]":"8.1","Tissue RNA - ovary [nTPM]":"24.4","Tissue RNA - pancreas [nTPM]":"20.2","Tissue RNA - parathyroid gland [nTPM]":"30.1","Tissue RNA - pituitary gland [nTPM]":"21.5","Tissue RNA - placenta [nTPM]":"16.5","Tissue RNA - pons [nTPM]":"9.5","Tissue RNA - prostate [nTPM]":"20.9","Tissue RNA - rectum [nTPM]":"15.2","Tissue RNA - retina [nTPM]":"26.5","Tissue RNA - salivary gland [nTPM]":"16.4","Tissue RNA - seminal vesicle [nTPM]":"17.2","Tissue RNA - skeletal muscle [nTPM]":"30.3","Tissue RNA - skin 1 [nTPM]":"17.2","Tissue RNA - small intestine [nTPM]":"13.4","Tissue RNA - smooth muscle [nTPM]":"15.2","Tissue RNA - spinal cord [nTPM]":"8.6","Tissue RNA - spleen [nTPM]":"15.0","Tissue RNA - stomach 1 [nTPM]":"17.6","Tissue RNA - testis [nTPM]":"21.3","Tissue RNA - thalamus [nTPM]":"8.2","Tissue RNA - thymus [nTPM]":"23.3","Tissue RNA - thyroid gland [nTPM]":"28.4","Tissue RNA - tongue [nTPM]":"23.6","Tissue RNA - tonsil [nTPM]":"18.0","Tissue RNA - urinary bladder [nTPM]":"16.9","Tissue RNA - vagina [nTPM]":"12.1","Tissue RNA - white matter [nTPM]":"12.2","Cell RNA - A-431 [nTPM]":"40.5","Cell RNA - A549 [nTPM]":"24.2","Cell RNA - AF22 [nTPM]":"34.1","Cell RNA - AN3-CA [nTPM]":"31.0","Cell RNA - ASC diff [nTPM]":"38.7","Cell RNA - ASC TERT1 [nTPM]":"34.5","Cell RNA - BEWO [nTPM]":"32.9","Cell RNA - BJ [nTPM]":"35.5","Cell RNA - BJ hTERT+ [nTPM]":"28.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"28.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"25.1","Cell RNA - CACO-2 [nTPM]":"60.7","Cell RNA - CAPAN-2 [nTPM]":"18.9","Cell RNA - Daudi [nTPM]":"63.2","Cell RNA - EFO-21 [nTPM]":"26.8","Cell RNA - fHDF\/TERT166 [nTPM]":"37.2","Cell RNA - GAMG [nTPM]":"35.3","Cell RNA - HaCaT [nTPM]":"33.1","Cell RNA - HAP1 [nTPM]":"58.9","Cell RNA - HBEC3-KT [nTPM]":"36.9","Cell RNA - HBF TERT88 [nTPM]":"41.5","Cell RNA - HDLM-2 [nTPM]":"38.9","Cell RNA - HEK 293 [nTPM]":"28.5","Cell RNA - HEL [nTPM]":"65.9","Cell RNA - HeLa [nTPM]":"30.3","Cell RNA - Hep G2 [nTPM]":"43.2","Cell RNA - HHSteC [nTPM]":"22.5","Cell RNA - HL-60 [nTPM]":"77.9","Cell RNA - HMC-1 [nTPM]":"21.3","Cell RNA - HSkMC [nTPM]":"29.1","Cell RNA - hTCEpi [nTPM]":"27.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"44.9","Cell RNA - hTERT-HME1 [nTPM]":"34.7","Cell RNA - hTERT-RPE1 [nTPM]":"28.3","Cell RNA - HUVEC TERT2 [nTPM]":"44.5","Cell RNA - JURKAT [nTPM]":"27.1","Cell RNA - K-562 [nTPM]":"71.9","Cell RNA - Karpas-707 [nTPM]":"34.0","Cell RNA - LHCN-M2 [nTPM]":"38.4","Cell RNA - MCF7 [nTPM]":"22.3","Cell RNA - MOLT-4 [nTPM]":"34.8","Cell RNA - NB-4 [nTPM]":"31.6","Cell RNA - NTERA-2 [nTPM]":"43.0","Cell RNA - OE19 [nTPM]":"20.3","Cell RNA - PC-3 [nTPM]":"28.7","Cell RNA - REH [nTPM]":"32.3","Cell RNA - RH-30 [nTPM]":"52.3","Cell RNA - RPMI-8226 [nTPM]":"30.7","Cell RNA - RPTEC TERT1 [nTPM]":"25.3","Cell RNA - RT4 [nTPM]":"49.6","Cell RNA - SCLC-21H [nTPM]":"49.4","Cell RNA - SH-SY5Y [nTPM]":"22.6","Cell RNA - SiHa [nTPM]":"31.5","Cell RNA - SK-BR-3 [nTPM]":"26.7","Cell RNA - SK-MEL-30 [nTPM]":"34.7","Cell RNA - SuSa [nTPM]":"20.4","Cell RNA - T-47d [nTPM]":"17.2","Cell RNA - THP-1 [nTPM]":"35.4","Cell RNA - TIME [nTPM]":"53.5","Cell RNA - U-138 MG [nTPM]":"29.8","Cell RNA - U-2 OS [nTPM]":"39.6","Cell RNA - U-2197 [nTPM]":"21.2","Cell RNA - U-251 MG [nTPM]":"40.2","Cell RNA - U-266\/70 [nTPM]":"27.9","Cell RNA - U-266\/84 [nTPM]":"44.4","Cell RNA - U-698 [nTPM]":"55.8","Cell RNA - U-87 MG [nTPM]":"23.1","Cell RNA - U-937 [nTPM]":"34.4","Cell RNA - WM-115 [nTPM]":"23.5","Blood RNA - basophil [nTPM]":"5.4","Blood RNA - classical monocyte [nTPM]":"2.6","Blood RNA - eosinophil [nTPM]":"2.7","Blood RNA - gdT-cell [nTPM]":"3.7","Blood RNA - intermediate monocyte [nTPM]":"1.7","Blood RNA - MAIT T-cell [nTPM]":"4.1","Blood RNA - memory B-cell [nTPM]":"2.7","Blood RNA - memory CD4 T-cell [nTPM]":"3.0","Blood RNA - memory CD8 T-cell [nTPM]":"3.4","Blood RNA - myeloid DC [nTPM]":"2.2","Blood RNA - naive B-cell [nTPM]":"2.7","Blood RNA - naive CD4 T-cell [nTPM]":"2.9","Blood RNA - naive CD8 T-cell [nTPM]":"3.3","Blood RNA - neutrophil [nTPM]":"3.9","Blood RNA - NK-cell [nTPM]":"2.2","Blood RNA - non-classical monocyte [nTPM]":"3.6","Blood RNA - plasmacytoid DC [nTPM]":"2.6","Blood RNA - T-reg [nTPM]":"2.7","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"8.6","Brain RNA - basal ganglia [nTPM]":"11.6","Brain RNA - cerebellum [nTPM]":"14.4","Brain RNA - cerebral cortex [nTPM]":"17.1","Brain RNA - hippocampal formation [nTPM]":"11.8","Brain RNA - hypothalamus [nTPM]":"9.4","Brain RNA - medulla oblongata [nTPM]":"9.2","Brain RNA - midbrain [nTPM]":"8.1","Brain RNA - pons [nTPM]":"9.5","Brain RNA - spinal cord [nTPM]":"8.6","Brain RNA - thalamus [nTPM]":"8.2","Brain RNA - white matter [nTPM]":"12.2","Single Cell Type RNA - Adipocytes [nTPM]":"54.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"76.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"85.3","Single Cell Type RNA - Astrocytes [nTPM]":"48.6","Single Cell Type RNA - B-cells [nTPM]":"91.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"55.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"34.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"39.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"61.5","Single Cell Type RNA - Bipolar cells [nTPM]":"51.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"34.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"25.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"103.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"63.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"58.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"73.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"28.8","Single Cell Type RNA - dendritic cells [nTPM]":"96.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"28.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"34.7","Single Cell Type RNA - Early spermatids [nTPM]":"77.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"83.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"65.3","Single Cell Type RNA - Endothelial cells [nTPM]":"55.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"106.4","Single Cell Type RNA - Erythroid cells [nTPM]":"50.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"125.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"50.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.5","Single Cell Type RNA - Fibroblasts [nTPM]":"56.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"68.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"142.1","Single Cell Type RNA - granulocytes [nTPM]":"84.9","Single Cell Type RNA - Granulosa cells [nTPM]":"52.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"31.4","Single Cell Type RNA - Hepatocytes [nTPM]":"56.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"47.9","Single Cell Type RNA - Horizontal cells [nTPM]":"32.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"92.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"59.5","Single Cell Type RNA - Ionocytes [nTPM]":"44.7","Single Cell Type RNA - Kupffer cells [nTPM]":"44.9","Single Cell Type RNA - Langerhans cells [nTPM]":"80.7","Single Cell Type RNA - Late spermatids [nTPM]":"32.9","Single Cell Type RNA - Leydig cells [nTPM]":"38.5","Single Cell Type RNA - Macrophages [nTPM]":"114.0","Single Cell Type RNA - Melanocytes [nTPM]":"48.0","Single Cell Type RNA - Microglial cells [nTPM]":"55.3","Single Cell Type RNA - monocytes [nTPM]":"57.0","Single Cell Type RNA - Muller glia cells [nTPM]":"20.0","Single Cell Type RNA - NK-cells [nTPM]":"34.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"44.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"80.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"41.5","Single Cell Type RNA - Paneth cells [nTPM]":"29.9","Single Cell Type RNA - Peritubular cells [nTPM]":"56.1","Single Cell Type RNA - Plasma cells [nTPM]":"118.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"44.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"28.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"67.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"40.5","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"56.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"59.0","Single Cell Type RNA - Spermatocytes [nTPM]":"78.3","Single Cell Type RNA - Spermatogonia [nTPM]":"65.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"53.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"67.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"40.6","Single Cell Type RNA - T-cells [nTPM]":"104.8","Single Cell Type RNA - Theca cells [nTPM]":"25.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"38.3","Single Cell Type RNA - Urothelial cells [nTPM]":"38.7"},{"Gene":"RARS1","Gene synonym":["DALRD1","RARS"],"Ensembl":"ENSG00000113643","Gene description":"Arginyl-tRNA synthetase 1","Uniprot":["P54136"],"Chromosome":"5","Position":"168486451-168519301","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Disease variant","Leukodystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Cardiomyocytes":"50.8","Cytotrophoblasts":"104.2","Extravillous trophoblasts":"96.8","Hofbauer cells":"57.2","Syncytiotrophoblasts":"84.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003979","HPA004130"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"74000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm","Nucleoli"],"Antibody RRID":{"HPA003979":"AB_1856083","HPA004130":"AB_1856084"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.59e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.10e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Tissue RNA - adipose tissue [nTPM]":"27.5","Tissue RNA - adrenal gland [nTPM]":"25.6","Tissue RNA - amygdala [nTPM]":"12.7","Tissue RNA - appendix [nTPM]":"31.5","Tissue RNA - basal ganglia [nTPM]":"12.3","Tissue RNA - bone marrow [nTPM]":"12.8","Tissue RNA - breast [nTPM]":"36.3","Tissue RNA - cerebellum [nTPM]":"19.6","Tissue RNA - cerebral cortex [nTPM]":"15.6","Tissue RNA - cervix [nTPM]":"22.9","Tissue RNA - choroid plexus [nTPM]":"9.4","Tissue RNA - colon [nTPM]":"37.6","Tissue RNA - duodenum [nTPM]":"54.8","Tissue RNA - endometrium 1 [nTPM]":"26.7","Tissue RNA - epididymis [nTPM]":"33.5","Tissue RNA - esophagus [nTPM]":"38.2","Tissue RNA - fallopian tube [nTPM]":"25.8","Tissue RNA - gallbladder [nTPM]":"23.4","Tissue RNA - heart muscle [nTPM]":"29.5","Tissue RNA - hippocampal formation [nTPM]":"12.8","Tissue RNA - hypothalamus [nTPM]":"11.2","Tissue RNA - kidney [nTPM]":"33.2","Tissue RNA - liver [nTPM]":"43.5","Tissue RNA - lung [nTPM]":"22.0","Tissue RNA - lymph node [nTPM]":"31.0","Tissue RNA - medulla oblongata [nTPM]":"9.0","Tissue RNA - midbrain [nTPM]":"10.7","Tissue RNA - ovary [nTPM]":"23.0","Tissue RNA - pancreas [nTPM]":"34.4","Tissue RNA - parathyroid gland [nTPM]":"32.7","Tissue RNA - pituitary gland [nTPM]":"16.6","Tissue RNA - placenta [nTPM]":"36.5","Tissue RNA - pons [nTPM]":"9.8","Tissue RNA - prostate [nTPM]":"27.9","Tissue RNA - rectum [nTPM]":"43.0","Tissue RNA - retina [nTPM]":"17.2","Tissue RNA - salivary gland [nTPM]":"32.9","Tissue RNA - seminal vesicle [nTPM]":"23.5","Tissue RNA - skeletal muscle [nTPM]":"31.1","Tissue RNA - skin 1 [nTPM]":"41.8","Tissue RNA - small intestine [nTPM]":"48.7","Tissue RNA - smooth muscle [nTPM]":"32.8","Tissue RNA - spinal cord [nTPM]":"5.4","Tissue RNA - spleen [nTPM]":"21.8","Tissue RNA - stomach 1 [nTPM]":"32.8","Tissue RNA - testis [nTPM]":"23.2","Tissue RNA - thalamus [nTPM]":"12.1","Tissue RNA - thymus [nTPM]":"23.5","Tissue RNA - thyroid gland [nTPM]":"30.2","Tissue RNA - tongue [nTPM]":"34.6","Tissue RNA - tonsil [nTPM]":"40.6","Tissue RNA - urinary bladder [nTPM]":"41.1","Tissue RNA - vagina [nTPM]":"25.2","Tissue RNA - white matter [nTPM]":"21.4","Cell RNA - A-431 [nTPM]":"100.2","Cell RNA - A549 [nTPM]":"115.6","Cell RNA - AF22 [nTPM]":"82.5","Cell RNA - AN3-CA [nTPM]":"94.2","Cell RNA - ASC diff [nTPM]":"113.4","Cell RNA - ASC TERT1 [nTPM]":"128.9","Cell RNA - BEWO [nTPM]":"143.9","Cell RNA - BJ [nTPM]":"143.4","Cell RNA - BJ hTERT+ [nTPM]":"122.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"145.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"168.7","Cell RNA - CACO-2 [nTPM]":"198.4","Cell RNA - CAPAN-2 [nTPM]":"105.6","Cell RNA - Daudi [nTPM]":"104.3","Cell RNA - EFO-21 [nTPM]":"114.2","Cell RNA - fHDF\/TERT166 [nTPM]":"137.2","Cell RNA - GAMG [nTPM]":"149.3","Cell RNA - HaCaT [nTPM]":"93.9","Cell RNA - HAP1 [nTPM]":"111.0","Cell RNA - HBEC3-KT [nTPM]":"192.7","Cell RNA - HBF TERT88 [nTPM]":"188.5","Cell RNA - HDLM-2 [nTPM]":"110.1","Cell RNA - HEK 293 [nTPM]":"76.5","Cell RNA - HEL [nTPM]":"71.2","Cell RNA - HeLa [nTPM]":"103.1","Cell RNA - Hep G2 [nTPM]":"126.5","Cell RNA - HHSteC [nTPM]":"96.8","Cell RNA - HL-60 [nTPM]":"169.2","Cell RNA - HMC-1 [nTPM]":"72.6","Cell RNA - HSkMC [nTPM]":"99.7","Cell RNA - hTCEpi [nTPM]":"100.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"159.0","Cell RNA - hTERT-HME1 [nTPM]":"76.0","Cell RNA - hTERT-RPE1 [nTPM]":"89.3","Cell RNA - HUVEC TERT2 [nTPM]":"118.5","Cell RNA - JURKAT [nTPM]":"56.4","Cell RNA - K-562 [nTPM]":"107.7","Cell RNA - Karpas-707 [nTPM]":"51.9","Cell RNA - LHCN-M2 [nTPM]":"158.1","Cell RNA - MCF7 [nTPM]":"92.4","Cell RNA - MOLT-4 [nTPM]":"70.7","Cell RNA - NB-4 [nTPM]":"68.7","Cell RNA - NTERA-2 [nTPM]":"138.1","Cell RNA - OE19 [nTPM]":"86.7","Cell RNA - PC-3 [nTPM]":"77.8","Cell RNA - REH [nTPM]":"30.3","Cell RNA - RH-30 [nTPM]":"122.0","Cell RNA - RPMI-8226 [nTPM]":"99.7","Cell RNA - RPTEC TERT1 [nTPM]":"129.7","Cell RNA - RT4 [nTPM]":"110.8","Cell RNA - SCLC-21H [nTPM]":"79.6","Cell RNA - SH-SY5Y [nTPM]":"97.7","Cell RNA - SiHa [nTPM]":"109.1","Cell RNA - SK-BR-3 [nTPM]":"124.7","Cell RNA - SK-MEL-30 [nTPM]":"152.7","Cell RNA - SuSa [nTPM]":"101.1","Cell RNA - T-47d [nTPM]":"113.4","Cell RNA - THP-1 [nTPM]":"69.9","Cell RNA - TIME [nTPM]":"118.7","Cell RNA - U-138 MG [nTPM]":"104.7","Cell RNA - U-2 OS [nTPM]":"96.3","Cell RNA - U-2197 [nTPM]":"81.9","Cell RNA - U-251 MG [nTPM]":"169.4","Cell RNA - U-266\/70 [nTPM]":"51.8","Cell RNA - U-266\/84 [nTPM]":"100.3","Cell RNA - U-698 [nTPM]":"105.7","Cell RNA - U-87 MG [nTPM]":"114.3","Cell RNA - U-937 [nTPM]":"118.0","Cell RNA - WM-115 [nTPM]":"101.9","Blood RNA - basophil [nTPM]":"5.2","Blood RNA - classical monocyte [nTPM]":"21.5","Blood RNA - eosinophil [nTPM]":"8.2","Blood RNA - gdT-cell [nTPM]":"17.4","Blood RNA - intermediate monocyte [nTPM]":"27.3","Blood RNA - MAIT T-cell [nTPM]":"20.2","Blood RNA - memory B-cell [nTPM]":"15.5","Blood RNA - memory CD4 T-cell [nTPM]":"17.2","Blood RNA - memory CD8 T-cell [nTPM]":"18.8","Blood RNA - myeloid DC [nTPM]":"32.1","Blood RNA - naive B-cell [nTPM]":"9.5","Blood RNA - naive CD4 T-cell [nTPM]":"21.2","Blood RNA - naive CD8 T-cell [nTPM]":"22.6","Blood RNA - neutrophil [nTPM]":"5.8","Blood RNA - NK-cell [nTPM]":"26.6","Blood RNA - non-classical monocyte [nTPM]":"26.7","Blood RNA - plasmacytoid DC [nTPM]":"14.7","Blood RNA - T-reg [nTPM]":"19.3","Blood RNA - total PBMC [nTPM]":"18.2","Brain RNA - amygdala [nTPM]":"12.7","Brain RNA - basal ganglia [nTPM]":"12.3","Brain RNA - cerebellum [nTPM]":"19.6","Brain RNA - cerebral cortex [nTPM]":"15.6","Brain RNA - hippocampal formation [nTPM]":"12.8","Brain RNA - hypothalamus [nTPM]":"11.2","Brain RNA - medulla oblongata [nTPM]":"9.0","Brain RNA - midbrain [nTPM]":"10.7","Brain RNA - pons [nTPM]":"9.8","Brain RNA - spinal cord [nTPM]":"5.4","Brain RNA - thalamus [nTPM]":"12.1","Brain RNA - white matter [nTPM]":"21.4","Single Cell Type RNA - Adipocytes [nTPM]":"10.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"50.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"104.2","Single Cell Type RNA - dendritic cells [nTPM]":"7.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"5.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"96.8","Single Cell Type RNA - Fibroblasts [nTPM]":"12.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"57.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"5.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"84.3","Single Cell Type RNA - T-cells [nTPM]":"1.4","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"RARS2","Gene synonym":["DALRD2","dJ382I10.6","MGC14993","MGC23778","PRO1992","RARSL"],"Ensembl":"ENSG00000146282","Gene description":"Arginyl-tRNA synthetase 2, mitochondrial","Uniprot":["Q5T160"],"Chromosome":"6","Position":"87513938-87589987","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Neurodegeneration","Pontocerebellar hypoplasia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039987","HPA042645"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA039987":"AB_2676786","HPA042645":"AB_2678097"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-3"},"Tissue RNA - adipose tissue [nTPM]":"24.0","Tissue RNA - adrenal gland [nTPM]":"39.6","Tissue RNA - amygdala [nTPM]":"10.8","Tissue RNA - appendix [nTPM]":"15.8","Tissue RNA - basal ganglia [nTPM]":"11.8","Tissue RNA - bone marrow [nTPM]":"19.3","Tissue RNA - breast [nTPM]":"21.3","Tissue RNA - cerebellum [nTPM]":"14.7","Tissue RNA - cerebral cortex [nTPM]":"11.6","Tissue RNA - cervix [nTPM]":"21.5","Tissue RNA - choroid plexus [nTPM]":"19.2","Tissue RNA - colon [nTPM]":"20.8","Tissue RNA - duodenum [nTPM]":"17.8","Tissue RNA - endometrium 1 [nTPM]":"21.8","Tissue RNA - epididymis [nTPM]":"18.6","Tissue RNA - esophagus [nTPM]":"17.7","Tissue RNA - fallopian tube [nTPM]":"19.7","Tissue RNA - gallbladder [nTPM]":"19.0","Tissue RNA - heart muscle [nTPM]":"22.7","Tissue RNA - hippocampal formation [nTPM]":"10.4","Tissue RNA - hypothalamus [nTPM]":"11.4","Tissue RNA - kidney [nTPM]":"20.5","Tissue RNA - liver [nTPM]":"27.9","Tissue RNA - lung [nTPM]":"18.3","Tissue RNA - lymph node [nTPM]":"16.8","Tissue RNA - medulla oblongata [nTPM]":"11.5","Tissue RNA - midbrain [nTPM]":"11.6","Tissue RNA - ovary [nTPM]":"18.5","Tissue RNA - pancreas [nTPM]":"24.0","Tissue RNA - parathyroid gland [nTPM]":"21.4","Tissue RNA - pituitary gland [nTPM]":"17.5","Tissue RNA - placenta [nTPM]":"22.2","Tissue RNA - pons [nTPM]":"11.8","Tissue RNA - prostate [nTPM]":"18.8","Tissue RNA - rectum [nTPM]":"22.7","Tissue RNA - retina [nTPM]":"25.9","Tissue RNA - salivary gland [nTPM]":"20.8","Tissue RNA - seminal vesicle [nTPM]":"13.6","Tissue RNA - skeletal muscle [nTPM]":"22.5","Tissue RNA - skin 1 [nTPM]":"18.5","Tissue RNA - small intestine [nTPM]":"22.6","Tissue RNA - smooth muscle [nTPM]":"21.5","Tissue RNA - spinal cord [nTPM]":"11.0","Tissue RNA - spleen [nTPM]":"18.5","Tissue RNA - stomach 1 [nTPM]":"19.2","Tissue RNA - testis [nTPM]":"25.3","Tissue RNA - thalamus [nTPM]":"12.5","Tissue RNA - thymus [nTPM]":"18.5","Tissue RNA - thyroid gland [nTPM]":"20.6","Tissue RNA - tongue [nTPM]":"19.3","Tissue RNA - tonsil [nTPM]":"19.0","Tissue RNA - urinary bladder [nTPM]":"20.6","Tissue RNA - vagina [nTPM]":"18.2","Tissue RNA - white matter [nTPM]":"15.5","Cell RNA - A-431 [nTPM]":"19.8","Cell RNA - A549 [nTPM]":"19.1","Cell RNA - AF22 [nTPM]":"45.1","Cell RNA - AN3-CA [nTPM]":"49.8","Cell RNA - ASC diff [nTPM]":"44.6","Cell RNA - ASC TERT1 [nTPM]":"47.5","Cell RNA - BEWO [nTPM]":"31.9","Cell RNA - BJ [nTPM]":"46.6","Cell RNA - BJ hTERT+ [nTPM]":"54.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"30.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"38.6","Cell RNA - CACO-2 [nTPM]":"36.6","Cell RNA - CAPAN-2 [nTPM]":"21.6","Cell RNA - Daudi [nTPM]":"25.0","Cell RNA - EFO-21 [nTPM]":"26.9","Cell RNA - fHDF\/TERT166 [nTPM]":"47.4","Cell RNA - GAMG [nTPM]":"32.0","Cell RNA - HaCaT [nTPM]":"26.7","Cell RNA - HAP1 [nTPM]":"37.9","Cell RNA - HBEC3-KT [nTPM]":"25.8","Cell RNA - HBF TERT88 [nTPM]":"43.2","Cell RNA - HDLM-2 [nTPM]":"18.0","Cell RNA - HEK 293 [nTPM]":"36.0","Cell RNA - HEL [nTPM]":"25.7","Cell RNA - HeLa [nTPM]":"24.4","Cell RNA - Hep G2 [nTPM]":"58.7","Cell RNA - HHSteC [nTPM]":"56.1","Cell RNA - HL-60 [nTPM]":"30.7","Cell RNA - HMC-1 [nTPM]":"21.3","Cell RNA - HSkMC [nTPM]":"48.9","Cell RNA - hTCEpi [nTPM]":"24.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.4","Cell RNA - hTERT-HME1 [nTPM]":"33.1","Cell RNA - hTERT-RPE1 [nTPM]":"44.5","Cell RNA - HUVEC TERT2 [nTPM]":"41.0","Cell RNA - JURKAT [nTPM]":"25.7","Cell RNA - K-562 [nTPM]":"59.6","Cell RNA - Karpas-707 [nTPM]":"24.4","Cell RNA - LHCN-M2 [nTPM]":"46.8","Cell RNA - MCF7 [nTPM]":"35.2","Cell RNA - MOLT-4 [nTPM]":"10.0","Cell RNA - NB-4 [nTPM]":"32.8","Cell RNA - NTERA-2 [nTPM]":"29.2","Cell RNA - OE19 [nTPM]":"42.3","Cell RNA - PC-3 [nTPM]":"20.0","Cell RNA - REH [nTPM]":"19.9","Cell RNA - RH-30 [nTPM]":"45.9","Cell RNA - RPMI-8226 [nTPM]":"22.2","Cell RNA - RPTEC TERT1 [nTPM]":"38.5","Cell RNA - RT4 [nTPM]":"40.1","Cell RNA - SCLC-21H [nTPM]":"40.8","Cell RNA - SH-SY5Y [nTPM]":"54.7","Cell RNA - SiHa [nTPM]":"24.8","Cell RNA - SK-BR-3 [nTPM]":"12.1","Cell RNA - SK-MEL-30 [nTPM]":"33.1","Cell RNA - SuSa [nTPM]":"38.2","Cell RNA - T-47d [nTPM]":"22.5","Cell RNA - THP-1 [nTPM]":"45.8","Cell RNA - TIME [nTPM]":"28.1","Cell RNA - U-138 MG [nTPM]":"21.2","Cell RNA - U-2 OS [nTPM]":"16.8","Cell RNA - U-2197 [nTPM]":"22.8","Cell RNA - U-251 MG [nTPM]":"38.4","Cell RNA - U-266\/70 [nTPM]":"25.6","Cell RNA - U-266\/84 [nTPM]":"45.1","Cell RNA - U-698 [nTPM]":"21.1","Cell RNA - U-87 MG [nTPM]":"32.2","Cell RNA - U-937 [nTPM]":"31.8","Cell RNA - WM-115 [nTPM]":"36.6","Blood RNA - basophil [nTPM]":"18.8","Blood RNA - classical monocyte [nTPM]":"17.8","Blood RNA - eosinophil [nTPM]":"22.7","Blood RNA - gdT-cell [nTPM]":"16.1","Blood RNA - intermediate monocyte [nTPM]":"18.6","Blood RNA - MAIT T-cell [nTPM]":"19.0","Blood RNA - memory B-cell [nTPM]":"15.1","Blood RNA - memory CD4 T-cell [nTPM]":"20.4","Blood RNA - memory CD8 T-cell [nTPM]":"15.1","Blood RNA - myeloid DC [nTPM]":"15.6","Blood RNA - naive B-cell [nTPM]":"16.2","Blood RNA - naive CD4 T-cell [nTPM]":"19.9","Blood RNA - naive CD8 T-cell [nTPM]":"16.9","Blood RNA - neutrophil [nTPM]":"11.9","Blood RNA - NK-cell [nTPM]":"18.6","Blood RNA - non-classical monocyte [nTPM]":"20.7","Blood RNA - plasmacytoid DC [nTPM]":"17.9","Blood RNA - T-reg [nTPM]":"27.9","Blood RNA - total PBMC [nTPM]":"15.4","Brain RNA - amygdala [nTPM]":"10.8","Brain RNA - basal ganglia [nTPM]":"11.8","Brain RNA - cerebellum [nTPM]":"14.7","Brain RNA - cerebral cortex [nTPM]":"11.6","Brain RNA - hippocampal formation [nTPM]":"10.4","Brain RNA - hypothalamus [nTPM]":"11.4","Brain RNA - medulla oblongata [nTPM]":"11.5","Brain RNA - midbrain [nTPM]":"11.6","Brain RNA - pons [nTPM]":"11.8","Brain RNA - spinal cord [nTPM]":"11.0","Brain RNA - thalamus [nTPM]":"12.5","Brain RNA - white matter [nTPM]":"15.5","Single Cell Type RNA - Adipocytes [nTPM]":"34.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.6","Single Cell Type RNA - Astrocytes [nTPM]":"30.0","Single Cell Type RNA - B-cells [nTPM]":"21.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"35.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"51.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Bipolar cells [nTPM]":"13.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"37.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"31.0","Single Cell Type RNA - dendritic cells [nTPM]":"18.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"45.0","Single Cell Type RNA - Ductal cells [nTPM]":"32.9","Single Cell Type RNA - Early spermatids [nTPM]":"95.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.3","Single Cell Type RNA - Endothelial cells [nTPM]":"22.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.0","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"46.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"46.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"45.5","Single Cell Type RNA - Fibroblasts [nTPM]":"28.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.3","Single Cell Type RNA - granulocytes [nTPM]":"18.3","Single Cell Type RNA - Granulosa cells [nTPM]":"27.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.6","Single Cell Type RNA - Hepatocytes [nTPM]":"15.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.5","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"59.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.5","Single Cell Type RNA - Ionocytes [nTPM]":"44.7","Single Cell Type RNA - Kupffer cells [nTPM]":"13.5","Single Cell Type RNA - Langerhans cells [nTPM]":"14.1","Single Cell Type RNA - Late spermatids [nTPM]":"50.6","Single Cell Type RNA - Leydig cells [nTPM]":"25.4","Single Cell Type RNA - Macrophages [nTPM]":"15.0","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"38.4","Single Cell Type RNA - monocytes [nTPM]":"22.6","Single Cell Type RNA - Muller glia cells [nTPM]":"13.6","Single Cell Type RNA - NK-cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"56.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"63.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"37.6","Single Cell Type RNA - Paneth cells [nTPM]":"21.2","Single Cell Type RNA - Peritubular cells [nTPM]":"24.0","Single Cell Type RNA - Plasma cells [nTPM]":"20.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"57.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"32.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"24.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"20.3","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"30.0","Single Cell Type RNA - Spermatocytes [nTPM]":"61.8","Single Cell Type RNA - Spermatogonia [nTPM]":"33.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"39.5","Single Cell Type RNA - T-cells [nTPM]":"20.6","Single Cell Type RNA - Theca cells [nTPM]":"51.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"27.0","Single Cell Type RNA - Urothelial cells [nTPM]":"33.9"},{"Gene":"RBCK1","Gene synonym":["C20orf18","HOIL1","RBCK2","RNF54","UBCE7IP3","XAP4","ZRANB4"],"Ensembl":"ENSG00000125826","Gene description":"RANBP2-type and C3HC4-type zinc finger containing 1","Uniprot":["Q9BYM8"],"Chromosome":"20","Position":"407498-432139","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Host-virus interaction","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTCEpi":"255.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.41e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-3"},"Tissue RNA - adipose tissue [nTPM]":"41.3","Tissue RNA - adrenal gland [nTPM]":"68.6","Tissue RNA - amygdala [nTPM]":"20.4","Tissue RNA - appendix [nTPM]":"28.8","Tissue RNA - basal ganglia [nTPM]":"23.3","Tissue RNA - bone marrow [nTPM]":"25.7","Tissue RNA - breast [nTPM]":"38.6","Tissue RNA - cerebellum [nTPM]":"26.6","Tissue RNA - cerebral cortex [nTPM]":"32.3","Tissue RNA - cervix [nTPM]":"48.5","Tissue RNA - choroid plexus [nTPM]":"16.9","Tissue RNA - colon [nTPM]":"50.2","Tissue RNA - duodenum [nTPM]":"34.6","Tissue RNA - endometrium 1 [nTPM]":"47.0","Tissue RNA - epididymis [nTPM]":"13.9","Tissue RNA - esophagus [nTPM]":"55.0","Tissue RNA - fallopian tube [nTPM]":"44.7","Tissue RNA - gallbladder [nTPM]":"19.4","Tissue RNA - heart muscle [nTPM]":"41.3","Tissue RNA - hippocampal formation [nTPM]":"20.2","Tissue RNA - hypothalamus [nTPM]":"20.8","Tissue RNA - kidney [nTPM]":"52.5","Tissue RNA - liver [nTPM]":"108.9","Tissue RNA - lung [nTPM]":"47.7","Tissue RNA - lymph node [nTPM]":"28.1","Tissue RNA - medulla oblongata [nTPM]":"27.9","Tissue RNA - midbrain [nTPM]":"22.1","Tissue RNA - ovary [nTPM]":"53.5","Tissue RNA - pancreas [nTPM]":"55.3","Tissue RNA - parathyroid gland [nTPM]":"30.1","Tissue RNA - pituitary gland [nTPM]":"64.1","Tissue RNA - placenta [nTPM]":"22.8","Tissue RNA - pons [nTPM]":"23.9","Tissue RNA - prostate [nTPM]":"56.0","Tissue RNA - rectum [nTPM]":"17.7","Tissue RNA - retina [nTPM]":"12.2","Tissue RNA - salivary gland [nTPM]":"41.9","Tissue RNA - seminal vesicle [nTPM]":"26.3","Tissue RNA - skeletal muscle [nTPM]":"38.6","Tissue RNA - skin 1 [nTPM]":"43.0","Tissue RNA - small intestine [nTPM]":"56.8","Tissue RNA - smooth muscle [nTPM]":"19.2","Tissue RNA - spinal cord [nTPM]":"20.3","Tissue RNA - spleen [nTPM]":"66.2","Tissue RNA - stomach 1 [nTPM]":"50.3","Tissue RNA - testis [nTPM]":"34.8","Tissue RNA - thalamus [nTPM]":"22.0","Tissue RNA - thymus [nTPM]":"43.7","Tissue RNA - thyroid gland [nTPM]":"46.7","Tissue RNA - tongue [nTPM]":"18.2","Tissue RNA - tonsil [nTPM]":"18.0","Tissue RNA - urinary bladder [nTPM]":"45.6","Tissue RNA - vagina [nTPM]":"46.8","Tissue RNA - white matter [nTPM]":"27.6","Cell RNA - A-431 [nTPM]":"64.0","Cell RNA - A549 [nTPM]":"88.4","Cell RNA - AF22 [nTPM]":"21.9","Cell RNA - AN3-CA [nTPM]":"37.2","Cell RNA - ASC diff [nTPM]":"44.3","Cell RNA - ASC TERT1 [nTPM]":"54.7","Cell RNA - BEWO [nTPM]":"44.9","Cell RNA - BJ [nTPM]":"34.2","Cell RNA - BJ hTERT+ [nTPM]":"55.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"56.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"73.4","Cell RNA - CACO-2 [nTPM]":"53.7","Cell RNA - CAPAN-2 [nTPM]":"74.1","Cell RNA - Daudi [nTPM]":"29.2","Cell RNA - EFO-21 [nTPM]":"51.3","Cell RNA - fHDF\/TERT166 [nTPM]":"70.7","Cell RNA - GAMG [nTPM]":"103.5","Cell RNA - HaCaT [nTPM]":"62.7","Cell RNA - HAP1 [nTPM]":"29.4","Cell RNA - HBEC3-KT [nTPM]":"151.0","Cell RNA - HBF TERT88 [nTPM]":"19.0","Cell RNA - HDLM-2 [nTPM]":"21.7","Cell RNA - HEK 293 [nTPM]":"29.8","Cell RNA - HEL [nTPM]":"30.2","Cell RNA - HeLa [nTPM]":"23.9","Cell RNA - Hep G2 [nTPM]":"140.9","Cell RNA - HHSteC [nTPM]":"185.3","Cell RNA - HL-60 [nTPM]":"28.4","Cell RNA - HMC-1 [nTPM]":"21.5","Cell RNA - HSkMC [nTPM]":"83.1","Cell RNA - hTCEpi [nTPM]":"255.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"43.0","Cell RNA - hTERT-HME1 [nTPM]":"173.2","Cell RNA - hTERT-RPE1 [nTPM]":"68.2","Cell RNA - HUVEC TERT2 [nTPM]":"50.8","Cell RNA - JURKAT [nTPM]":"109.8","Cell RNA - K-562 [nTPM]":"29.6","Cell RNA - Karpas-707 [nTPM]":"55.0","Cell RNA - LHCN-M2 [nTPM]":"40.7","Cell RNA - MCF7 [nTPM]":"33.2","Cell RNA - MOLT-4 [nTPM]":"61.5","Cell RNA - NB-4 [nTPM]":"69.9","Cell RNA - NTERA-2 [nTPM]":"18.4","Cell RNA - OE19 [nTPM]":"77.4","Cell RNA - PC-3 [nTPM]":"73.0","Cell RNA - REH [nTPM]":"40.3","Cell RNA - RH-30 [nTPM]":"21.8","Cell RNA - RPMI-8226 [nTPM]":"37.3","Cell RNA - RPTEC TERT1 [nTPM]":"72.7","Cell RNA - RT4 [nTPM]":"57.5","Cell RNA - SCLC-21H [nTPM]":"41.3","Cell RNA - SH-SY5Y [nTPM]":"35.9","Cell RNA - SiHa [nTPM]":"24.1","Cell RNA - SK-BR-3 [nTPM]":"122.4","Cell RNA - SK-MEL-30 [nTPM]":"140.7","Cell RNA - SuSa [nTPM]":"25.0","Cell RNA - T-47d [nTPM]":"73.3","Cell RNA - THP-1 [nTPM]":"64.2","Cell RNA - TIME [nTPM]":"31.0","Cell RNA - U-138 MG [nTPM]":"54.5","Cell RNA - U-2 OS [nTPM]":"27.0","Cell RNA - U-2197 [nTPM]":"33.2","Cell RNA - U-251 MG [nTPM]":"46.5","Cell RNA - U-266\/70 [nTPM]":"44.4","Cell RNA - U-266\/84 [nTPM]":"61.6","Cell RNA - U-698 [nTPM]":"35.6","Cell RNA - U-87 MG [nTPM]":"24.5","Cell RNA - U-937 [nTPM]":"61.4","Cell RNA - WM-115 [nTPM]":"39.0","Blood RNA - basophil [nTPM]":"56.5","Blood RNA - classical monocyte [nTPM]":"48.8","Blood RNA - eosinophil [nTPM]":"85.4","Blood RNA - gdT-cell [nTPM]":"61.9","Blood RNA - intermediate monocyte [nTPM]":"71.3","Blood RNA - MAIT T-cell [nTPM]":"43.5","Blood RNA - memory B-cell [nTPM]":"48.1","Blood RNA - memory CD4 T-cell [nTPM]":"48.0","Blood RNA - memory CD8 T-cell [nTPM]":"63.1","Blood RNA - myeloid DC [nTPM]":"43.6","Blood RNA - naive B-cell [nTPM]":"46.8","Blood RNA - naive CD4 T-cell [nTPM]":"38.7","Blood RNA - naive CD8 T-cell [nTPM]":"45.2","Blood RNA - neutrophil [nTPM]":"135.6","Blood RNA - NK-cell [nTPM]":"52.4","Blood RNA - non-classical monocyte [nTPM]":"83.9","Blood RNA - plasmacytoid DC [nTPM]":"72.1","Blood RNA - T-reg [nTPM]":"55.7","Blood RNA - total PBMC [nTPM]":"52.7","Brain RNA - amygdala [nTPM]":"20.4","Brain RNA - basal ganglia [nTPM]":"23.3","Brain RNA - cerebellum [nTPM]":"26.6","Brain RNA - cerebral cortex [nTPM]":"32.3","Brain RNA - hippocampal formation [nTPM]":"20.2","Brain RNA - hypothalamus [nTPM]":"20.8","Brain RNA - medulla oblongata [nTPM]":"27.9","Brain RNA - midbrain [nTPM]":"22.1","Brain RNA - pons [nTPM]":"23.9","Brain RNA - spinal cord [nTPM]":"20.3","Brain RNA - thalamus [nTPM]":"22.0","Brain RNA - white matter [nTPM]":"27.6","Single Cell Type RNA - Adipocytes [nTPM]":"69.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"39.8","Single Cell Type RNA - Astrocytes [nTPM]":"40.8","Single Cell Type RNA - B-cells [nTPM]":"54.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"44.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"77.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"96.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"49.5","Single Cell Type RNA - Bipolar cells [nTPM]":"15.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"65.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"66.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"64.3","Single Cell Type RNA - Club cells [nTPM]":"48.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"57.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"88.7","Single Cell Type RNA - dendritic cells [nTPM]":"72.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"111.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"62.6","Single Cell Type RNA - Ductal cells [nTPM]":"111.7","Single Cell Type RNA - Early spermatids [nTPM]":"58.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"40.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"45.3","Single Cell Type RNA - Endothelial cells [nTPM]":"59.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"61.7","Single Cell Type RNA - Erythroid cells [nTPM]":"43.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"116.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"102.4","Single Cell Type RNA - Fibroblasts [nTPM]":"52.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"50.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"54.3","Single Cell Type RNA - granulocytes [nTPM]":"43.8","Single Cell Type RNA - Granulosa cells [nTPM]":"62.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"57.1","Single Cell Type RNA - Hepatocytes [nTPM]":"139.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"66.8","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"122.8","Single Cell Type RNA - Ionocytes [nTPM]":"46.8","Single Cell Type RNA - Kupffer cells [nTPM]":"69.8","Single Cell Type RNA - Langerhans cells [nTPM]":"44.2","Single Cell Type RNA - Late spermatids [nTPM]":"163.3","Single Cell Type RNA - Leydig cells [nTPM]":"65.9","Single Cell Type RNA - Macrophages [nTPM]":"57.2","Single Cell Type RNA - Melanocytes [nTPM]":"42.7","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"69.1","Single Cell Type RNA - Muller glia cells [nTPM]":"45.1","Single Cell Type RNA - NK-cells [nTPM]":"106.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"22.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"24.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"108.5","Single Cell Type RNA - Paneth cells [nTPM]":"161.0","Single Cell Type RNA - Peritubular cells [nTPM]":"47.8","Single Cell Type RNA - Plasma cells [nTPM]":"30.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"98.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"185.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"74.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"39.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"29.0","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"56.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"51.9","Single Cell Type RNA - Spermatocytes [nTPM]":"32.6","Single Cell Type RNA - Spermatogonia [nTPM]":"29.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"69.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"40.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"94.7","Single Cell Type RNA - T-cells [nTPM]":"71.0","Single Cell Type RNA - Theca cells [nTPM]":"110.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"74.2","Single Cell Type RNA - Urothelial cells [nTPM]":"120.3"},{"Gene":"RBM8A","Gene synonym":["BOV-1A","BOV-1B","BOV-1C","RBM8","RBM8B","Y14","ZNRP"],"Ensembl":"ENSG00000265241","Gene description":"RNA binding motif protein 8A","Uniprot":["Q9Y5S9"],"Chromosome":"1","Position":"145917714-145927678","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["mRNA processing","mRNA splicing","mRNA transport","Nonsense-mediated mRNA decay","Translation regulation","Transport"],"Molecular function":["RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"735.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018403"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"100000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA018403":"AB_1858908"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.79e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.27e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.55e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-3"},"Tissue RNA - adipose tissue [nTPM]":"86.1","Tissue RNA - adrenal gland [nTPM]":"74.9","Tissue RNA - amygdala [nTPM]":"37.2","Tissue RNA - appendix [nTPM]":"105.4","Tissue RNA - basal ganglia [nTPM]":"39.1","Tissue RNA - bone marrow [nTPM]":"214.7","Tissue RNA - breast [nTPM]":"82.3","Tissue RNA - cerebellum [nTPM]":"38.7","Tissue RNA - cerebral cortex [nTPM]":"43.0","Tissue RNA - cervix [nTPM]":"69.6","Tissue RNA - choroid plexus [nTPM]":"35.6","Tissue RNA - colon [nTPM]":"70.5","Tissue RNA - duodenum [nTPM]":"70.1","Tissue RNA - endometrium 1 [nTPM]":"67.7","Tissue RNA - epididymis [nTPM]":"49.3","Tissue RNA - esophagus [nTPM]":"163.6","Tissue RNA - fallopian tube [nTPM]":"62.2","Tissue RNA - gallbladder [nTPM]":"58.0","Tissue RNA - heart muscle [nTPM]":"73.0","Tissue RNA - hippocampal formation [nTPM]":"36.8","Tissue RNA - hypothalamus [nTPM]":"41.7","Tissue RNA - kidney [nTPM]":"81.6","Tissue RNA - liver [nTPM]":"77.5","Tissue RNA - lung [nTPM]":"72.8","Tissue RNA - lymph node [nTPM]":"126.4","Tissue RNA - medulla oblongata [nTPM]":"39.7","Tissue RNA - midbrain [nTPM]":"39.8","Tissue RNA - ovary [nTPM]":"72.0","Tissue RNA - pancreas [nTPM]":"59.9","Tissue RNA - parathyroid gland [nTPM]":"78.4","Tissue RNA - pituitary gland [nTPM]":"65.8","Tissue RNA - placenta [nTPM]":"85.3","Tissue RNA - pons [nTPM]":"40.8","Tissue RNA - prostate [nTPM]":"66.4","Tissue RNA - rectum [nTPM]":"56.4","Tissue RNA - retina [nTPM]":"45.0","Tissue RNA - salivary gland [nTPM]":"79.2","Tissue RNA - seminal vesicle [nTPM]":"48.2","Tissue RNA - skeletal muscle [nTPM]":"214.9","Tissue RNA - skin 1 [nTPM]":"92.0","Tissue RNA - small intestine [nTPM]":"69.2","Tissue RNA - smooth muscle [nTPM]":"57.7","Tissue RNA - spinal cord [nTPM]":"42.1","Tissue RNA - spleen [nTPM]":"81.6","Tissue RNA - stomach 1 [nTPM]":"67.5","Tissue RNA - testis [nTPM]":"71.3","Tissue RNA - thalamus [nTPM]":"40.0","Tissue RNA - thymus [nTPM]":"120.7","Tissue RNA - thyroid gland [nTPM]":"68.8","Tissue RNA - tongue [nTPM]":"100.1","Tissue RNA - tonsil [nTPM]":"123.7","Tissue RNA - urinary bladder [nTPM]":"112.8","Tissue RNA - vagina [nTPM]":"80.4","Tissue RNA - white matter [nTPM]":"43.9","Cell RNA - A-431 [nTPM]":"377.0","Cell RNA - A549 [nTPM]":"300.7","Cell RNA - AF22 [nTPM]":"268.8","Cell RNA - AN3-CA [nTPM]":"215.7","Cell RNA - ASC diff [nTPM]":"94.6","Cell RNA - ASC TERT1 [nTPM]":"92.2","Cell RNA - BEWO [nTPM]":"330.0","Cell RNA - BJ [nTPM]":"224.3","Cell RNA - BJ hTERT+ [nTPM]":"150.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"315.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"230.1","Cell RNA - CACO-2 [nTPM]":"400.0","Cell RNA - CAPAN-2 [nTPM]":"277.4","Cell RNA - Daudi [nTPM]":"342.0","Cell RNA - EFO-21 [nTPM]":"344.9","Cell RNA - fHDF\/TERT166 [nTPM]":"155.3","Cell RNA - GAMG [nTPM]":"166.5","Cell RNA - HaCaT [nTPM]":"252.5","Cell RNA - HAP1 [nTPM]":"289.3","Cell RNA - HBEC3-KT [nTPM]":"245.3","Cell RNA - HBF TERT88 [nTPM]":"257.0","Cell RNA - HDLM-2 [nTPM]":"305.6","Cell RNA - HEK 293 [nTPM]":"275.7","Cell RNA - HEL [nTPM]":"264.2","Cell RNA - HeLa [nTPM]":"229.2","Cell RNA - Hep G2 [nTPM]":"299.8","Cell RNA - HHSteC [nTPM]":"133.6","Cell RNA - HL-60 [nTPM]":"446.6","Cell RNA - HMC-1 [nTPM]":"222.6","Cell RNA - HSkMC [nTPM]":"102.2","Cell RNA - hTCEpi [nTPM]":"180.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"283.0","Cell RNA - hTERT-HME1 [nTPM]":"300.3","Cell RNA - hTERT-RPE1 [nTPM]":"137.4","Cell RNA - HUVEC TERT2 [nTPM]":"238.1","Cell RNA - JURKAT [nTPM]":"291.9","Cell RNA - K-562 [nTPM]":"405.2","Cell RNA - Karpas-707 [nTPM]":"314.7","Cell RNA - LHCN-M2 [nTPM]":"246.2","Cell RNA - MCF7 [nTPM]":"1033.8","Cell RNA - MOLT-4 [nTPM]":"452.3","Cell RNA - NB-4 [nTPM]":"352.2","Cell RNA - NTERA-2 [nTPM]":"463.7","Cell RNA - OE19 [nTPM]":"323.9","Cell RNA - PC-3 [nTPM]":"518.4","Cell RNA - REH [nTPM]":"394.4","Cell RNA - RH-30 [nTPM]":"234.6","Cell RNA - RPMI-8226 [nTPM]":"341.2","Cell RNA - RPTEC TERT1 [nTPM]":"203.2","Cell RNA - RT4 [nTPM]":"355.6","Cell RNA - SCLC-21H [nTPM]":"274.6","Cell RNA - SH-SY5Y [nTPM]":"335.7","Cell RNA - SiHa [nTPM]":"334.5","Cell RNA - SK-BR-3 [nTPM]":"169.7","Cell RNA - SK-MEL-30 [nTPM]":"316.5","Cell RNA - SuSa [nTPM]":"231.0","Cell RNA - T-47d [nTPM]":"318.0","Cell RNA - THP-1 [nTPM]":"534.3","Cell RNA - TIME [nTPM]":"247.3","Cell RNA - U-138 MG [nTPM]":"252.3","Cell RNA - U-2 OS [nTPM]":"324.0","Cell RNA - U-2197 [nTPM]":"250.9","Cell RNA - U-251 MG [nTPM]":"626.0","Cell RNA - U-266\/70 [nTPM]":"352.2","Cell RNA - U-266\/84 [nTPM]":"603.4","Cell RNA - U-698 [nTPM]":"502.6","Cell RNA - U-87 MG [nTPM]":"226.4","Cell RNA - U-937 [nTPM]":"264.9","Cell RNA - WM-115 [nTPM]":"223.2","Blood RNA - basophil [nTPM]":"464.6","Blood RNA - classical monocyte [nTPM]":"316.5","Blood RNA - eosinophil [nTPM]":"513.6","Blood RNA - gdT-cell [nTPM]":"337.2","Blood RNA - intermediate monocyte [nTPM]":"363.9","Blood RNA - MAIT T-cell [nTPM]":"322.1","Blood RNA - memory B-cell [nTPM]":"444.3","Blood RNA - memory CD4 T-cell [nTPM]":"317.6","Blood RNA - memory CD8 T-cell [nTPM]":"346.4","Blood RNA - myeloid DC [nTPM]":"318.0","Blood RNA - naive B-cell [nTPM]":"389.6","Blood RNA - naive CD4 T-cell [nTPM]":"296.1","Blood RNA - naive CD8 T-cell [nTPM]":"328.3","Blood RNA - neutrophil [nTPM]":"363.7","Blood RNA - NK-cell [nTPM]":"389.8","Blood RNA - non-classical monocyte [nTPM]":"361.3","Blood RNA - plasmacytoid DC [nTPM]":"498.4","Blood RNA - T-reg [nTPM]":"386.3","Blood RNA - total PBMC [nTPM]":"582.7","Brain RNA - amygdala [nTPM]":"37.2","Brain RNA - basal ganglia [nTPM]":"39.1","Brain RNA - cerebellum [nTPM]":"38.7","Brain RNA - cerebral cortex [nTPM]":"43.0","Brain RNA - hippocampal formation [nTPM]":"36.8","Brain RNA - hypothalamus [nTPM]":"41.7","Brain RNA - medulla oblongata [nTPM]":"39.7","Brain RNA - midbrain [nTPM]":"39.8","Brain RNA - pons [nTPM]":"40.8","Brain RNA - spinal cord [nTPM]":"42.1","Brain RNA - thalamus [nTPM]":"40.0","Brain RNA - white matter [nTPM]":"43.9","Single Cell Type RNA - Adipocytes [nTPM]":"289.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"70.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"132.4","Single Cell Type RNA - Astrocytes [nTPM]":"8.1","Single Cell Type RNA - B-cells [nTPM]":"251.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"332.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"396.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"475.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"244.2","Single Cell Type RNA - Bipolar cells [nTPM]":"66.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"168.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"184.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"78.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"98.7","Single Cell Type RNA - Club cells [nTPM]":"262.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"88.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"54.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"376.2","Single Cell Type RNA - dendritic cells [nTPM]":"276.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"125.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"187.9","Single Cell Type RNA - Ductal cells [nTPM]":"224.1","Single Cell Type RNA - Early spermatids [nTPM]":"243.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"148.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"134.3","Single Cell Type RNA - Endothelial cells [nTPM]":"206.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"158.9","Single Cell Type RNA - Erythroid cells [nTPM]":"149.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"223.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"506.3","Single Cell Type RNA - Fibroblasts [nTPM]":"174.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"80.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"152.8","Single Cell Type RNA - granulocytes [nTPM]":"244.0","Single Cell Type RNA - Granulosa cells [nTPM]":"136.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"120.3","Single Cell Type RNA - Hepatocytes [nTPM]":"124.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"204.3","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"127.6","Single Cell Type RNA - Ionocytes [nTPM]":"313.3","Single Cell Type RNA - Kupffer cells [nTPM]":"100.3","Single Cell Type RNA - Langerhans cells [nTPM]":"265.2","Single Cell Type RNA - Late spermatids [nTPM]":"54.4","Single Cell Type RNA - Leydig cells [nTPM]":"102.2","Single Cell Type RNA - Macrophages [nTPM]":"170.7","Single Cell Type RNA - Melanocytes [nTPM]":"208.1","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"197.7","Single Cell Type RNA - Muller glia cells [nTPM]":"120.3","Single Cell Type RNA - NK-cells [nTPM]":"165.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"245.4","Single Cell Type RNA - Paneth cells [nTPM]":"159.8","Single Cell Type RNA - Peritubular cells [nTPM]":"85.4","Single Cell Type RNA - Plasma cells [nTPM]":"174.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"259.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"119.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"204.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"195.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"86.3","Single Cell Type RNA - Sertoli cells [nTPM]":"98.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"213.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"208.1","Single Cell Type RNA - Spermatocytes [nTPM]":"212.0","Single Cell Type RNA - Spermatogonia [nTPM]":"168.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"208.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"318.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"735.5","Single Cell Type RNA - T-cells [nTPM]":"282.1","Single Cell Type RNA - Theca cells [nTPM]":"139.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"141.7","Single Cell Type RNA - Urothelial cells [nTPM]":"393.0"},{"Gene":"RBP3","Gene synonym":["D10S64","D10S65","D10S66","RP66"],"Ensembl":"ENSG00000265203","Gene description":"Retinol binding protein 3","Uniprot":["P10745"],"Chromosome":"10","Position":"47348363-47357881","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted secreted proteins"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"335","RNA tissue specific nTPM":{"retina":"542.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"2070.4","Rod photoreceptor cells":"1610.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hippocampal formation":"1.3"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041301","HPA044239"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041301":"AB_2677398","HPA044239":"AB_2678868"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.9","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"1.2","Tissue RNA - hypothalamus [nTPM]":"1.6","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.6","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"542.3","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"1.2","Brain RNA - hypothalamus [nTPM]":"1.6","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.6","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"0.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"157.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2070.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"7.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"43.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"148.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1610.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"RDH11","Gene synonym":["ARSDR1","MDT1","SDR7C1"],"Ensembl":"ENSG00000072042","Gene description":"Retinol dehydrogenase 11","Uniprot":["Q8TC12"],"Chromosome":"14","Position":"67676800-67695793","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Cataract","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"prostate":"582.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"241.8","Muller glia cells":"299.7","Prostatic glandular cells":"285.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"13","RNA cancer specific FPKM":{"prostate cancer":"286.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB046011"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"340000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 5: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB046011":"AB_11129613"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.86e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.62e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.89e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.30e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Tissue RNA - adipose tissue [nTPM]":"23.6","Tissue RNA - adrenal gland [nTPM]":"59.5","Tissue RNA - amygdala [nTPM]":"39.3","Tissue RNA - appendix [nTPM]":"24.5","Tissue RNA - basal ganglia [nTPM]":"43.2","Tissue RNA - bone marrow [nTPM]":"13.9","Tissue RNA - breast [nTPM]":"28.7","Tissue RNA - cerebellum [nTPM]":"50.2","Tissue RNA - cerebral cortex [nTPM]":"54.4","Tissue RNA - cervix [nTPM]":"32.6","Tissue RNA - choroid plexus [nTPM]":"35.9","Tissue RNA - colon [nTPM]":"29.2","Tissue RNA - duodenum [nTPM]":"34.1","Tissue RNA - endometrium 1 [nTPM]":"33.2","Tissue RNA - epididymis [nTPM]":"86.0","Tissue RNA - esophagus [nTPM]":"34.6","Tissue RNA - fallopian tube [nTPM]":"23.5","Tissue RNA - gallbladder [nTPM]":"42.7","Tissue RNA - heart muscle [nTPM]":"17.6","Tissue RNA - hippocampal formation [nTPM]":"40.4","Tissue RNA - hypothalamus [nTPM]":"47.2","Tissue RNA - kidney [nTPM]":"106.0","Tissue RNA - liver [nTPM]":"153.1","Tissue RNA - lung [nTPM]":"34.9","Tissue RNA - lymph node [nTPM]":"20.4","Tissue RNA - medulla oblongata [nTPM]":"49.2","Tissue RNA - midbrain [nTPM]":"47.7","Tissue RNA - ovary [nTPM]":"28.9","Tissue RNA - pancreas [nTPM]":"42.6","Tissue RNA - parathyroid gland [nTPM]":"79.8","Tissue RNA - pituitary gland [nTPM]":"23.4","Tissue RNA - placenta [nTPM]":"21.9","Tissue RNA - pons [nTPM]":"49.3","Tissue RNA - prostate [nTPM]":"582.0","Tissue RNA - rectum [nTPM]":"31.4","Tissue RNA - retina [nTPM]":"73.9","Tissue RNA - salivary gland [nTPM]":"44.2","Tissue RNA - seminal vesicle [nTPM]":"34.4","Tissue RNA - skeletal muscle [nTPM]":"8.3","Tissue RNA - skin 1 [nTPM]":"31.4","Tissue RNA - small intestine [nTPM]":"23.9","Tissue RNA - smooth muscle [nTPM]":"43.6","Tissue RNA - spinal cord [nTPM]":"49.8","Tissue RNA - spleen [nTPM]":"22.2","Tissue RNA - stomach 1 [nTPM]":"31.9","Tissue RNA - testis [nTPM]":"28.4","Tissue RNA - thalamus [nTPM]":"46.1","Tissue RNA - thymus [nTPM]":"30.7","Tissue RNA - thyroid gland [nTPM]":"61.7","Tissue RNA - tongue [nTPM]":"13.5","Tissue RNA - tonsil [nTPM]":"26.2","Tissue RNA - urinary bladder [nTPM]":"34.3","Tissue RNA - vagina [nTPM]":"30.3","Tissue RNA - white matter [nTPM]":"58.4","Cell RNA - A-431 [nTPM]":"183.7","Cell RNA - A549 [nTPM]":"81.9","Cell RNA - AF22 [nTPM]":"71.3","Cell RNA - AN3-CA [nTPM]":"82.0","Cell RNA - ASC diff [nTPM]":"111.5","Cell RNA - ASC TERT1 [nTPM]":"100.4","Cell RNA - BEWO [nTPM]":"59.3","Cell RNA - BJ [nTPM]":"68.0","Cell RNA - BJ hTERT+ [nTPM]":"134.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"83.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"150.9","Cell RNA - CACO-2 [nTPM]":"68.6","Cell RNA - CAPAN-2 [nTPM]":"216.7","Cell RNA - Daudi [nTPM]":"31.7","Cell RNA - EFO-21 [nTPM]":"51.2","Cell RNA - fHDF\/TERT166 [nTPM]":"64.6","Cell RNA - GAMG [nTPM]":"104.8","Cell RNA - HaCaT [nTPM]":"142.5","Cell RNA - HAP1 [nTPM]":"104.0","Cell RNA - HBEC3-KT [nTPM]":"150.8","Cell RNA - HBF TERT88 [nTPM]":"113.7","Cell RNA - HDLM-2 [nTPM]":"63.0","Cell RNA - HEK 293 [nTPM]":"42.6","Cell RNA - HEL [nTPM]":"65.1","Cell RNA - HeLa [nTPM]":"40.7","Cell RNA - Hep G2 [nTPM]":"69.0","Cell RNA - HHSteC [nTPM]":"106.9","Cell RNA - HL-60 [nTPM]":"24.3","Cell RNA - HMC-1 [nTPM]":"46.0","Cell RNA - HSkMC [nTPM]":"94.4","Cell RNA - hTCEpi [nTPM]":"98.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"109.3","Cell RNA - hTERT-HME1 [nTPM]":"92.0","Cell RNA - hTERT-RPE1 [nTPM]":"63.9","Cell RNA - HUVEC TERT2 [nTPM]":"97.4","Cell RNA - JURKAT [nTPM]":"87.0","Cell RNA - K-562 [nTPM]":"52.1","Cell RNA - Karpas-707 [nTPM]":"101.1","Cell RNA - LHCN-M2 [nTPM]":"77.2","Cell RNA - MCF7 [nTPM]":"97.5","Cell RNA - MOLT-4 [nTPM]":"72.2","Cell RNA - NB-4 [nTPM]":"38.8","Cell RNA - NTERA-2 [nTPM]":"40.4","Cell RNA - OE19 [nTPM]":"49.7","Cell RNA - PC-3 [nTPM]":"92.8","Cell RNA - REH [nTPM]":"53.6","Cell RNA - RH-30 [nTPM]":"87.4","Cell RNA - RPMI-8226 [nTPM]":"45.8","Cell RNA - RPTEC TERT1 [nTPM]":"194.1","Cell RNA - RT4 [nTPM]":"93.0","Cell RNA - SCLC-21H [nTPM]":"73.8","Cell RNA - SH-SY5Y [nTPM]":"62.0","Cell RNA - SiHa [nTPM]":"71.2","Cell RNA - SK-BR-3 [nTPM]":"89.7","Cell RNA - SK-MEL-30 [nTPM]":"99.1","Cell RNA - SuSa [nTPM]":"58.2","Cell RNA - T-47d [nTPM]":"100.7","Cell RNA - THP-1 [nTPM]":"38.3","Cell RNA - TIME [nTPM]":"74.2","Cell RNA - U-138 MG [nTPM]":"89.5","Cell RNA - U-2 OS [nTPM]":"101.1","Cell RNA - U-2197 [nTPM]":"38.9","Cell RNA - U-251 MG [nTPM]":"49.5","Cell RNA - U-266\/70 [nTPM]":"47.5","Cell RNA - U-266\/84 [nTPM]":"40.0","Cell RNA - U-698 [nTPM]":"40.7","Cell RNA - U-87 MG [nTPM]":"115.8","Cell RNA - U-937 [nTPM]":"66.0","Cell RNA - WM-115 [nTPM]":"74.3","Blood RNA - basophil [nTPM]":"282.4","Blood RNA - classical monocyte [nTPM]":"71.1","Blood RNA - eosinophil [nTPM]":"104.0","Blood RNA - gdT-cell [nTPM]":"62.3","Blood RNA - intermediate monocyte [nTPM]":"57.7","Blood RNA - MAIT T-cell [nTPM]":"68.2","Blood RNA - memory B-cell [nTPM]":"39.0","Blood RNA - memory CD4 T-cell [nTPM]":"67.7","Blood RNA - memory CD8 T-cell [nTPM]":"61.5","Blood RNA - myeloid DC [nTPM]":"51.3","Blood RNA - naive B-cell [nTPM]":"45.5","Blood RNA - naive CD4 T-cell [nTPM]":"67.3","Blood RNA - naive CD8 T-cell [nTPM]":"64.8","Blood RNA - neutrophil [nTPM]":"11.0","Blood RNA - NK-cell [nTPM]":"56.3","Blood RNA - non-classical monocyte [nTPM]":"65.4","Blood RNA - plasmacytoid DC [nTPM]":"59.1","Blood RNA - T-reg [nTPM]":"65.1","Blood RNA - total PBMC [nTPM]":"115.8","Brain RNA - amygdala [nTPM]":"39.3","Brain RNA - basal ganglia [nTPM]":"43.2","Brain RNA - cerebellum [nTPM]":"50.2","Brain RNA - cerebral cortex [nTPM]":"54.4","Brain RNA - hippocampal formation [nTPM]":"40.4","Brain RNA - hypothalamus [nTPM]":"47.2","Brain RNA - medulla oblongata [nTPM]":"49.2","Brain RNA - midbrain [nTPM]":"47.7","Brain RNA - pons [nTPM]":"49.3","Brain RNA - spinal cord [nTPM]":"49.8","Brain RNA - thalamus [nTPM]":"46.1","Brain RNA - white matter [nTPM]":"58.4","Single Cell Type RNA - Adipocytes [nTPM]":"27.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"66.0","Single Cell Type RNA - Astrocytes [nTPM]":"38.2","Single Cell Type RNA - B-cells [nTPM]":"29.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"40.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"77.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"16.5","Single Cell Type RNA - Bipolar cells [nTPM]":"53.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"45.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"20.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"68.6","Single Cell Type RNA - Club cells [nTPM]":"59.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"47.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"50.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"24.9","Single Cell Type RNA - dendritic cells [nTPM]":"32.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"26.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"92.5","Single Cell Type RNA - Early spermatids [nTPM]":"2.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"21.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"50.9","Single Cell Type RNA - Endothelial cells [nTPM]":"39.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"43.3","Single Cell Type RNA - Erythroid cells [nTPM]":"29.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"33.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"84.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"38.1","Single Cell Type RNA - Fibroblasts [nTPM]":"37.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"38.2","Single Cell Type RNA - granulocytes [nTPM]":"29.2","Single Cell Type RNA - Granulosa cells [nTPM]":"46.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"47.8","Single Cell Type RNA - Hepatocytes [nTPM]":"241.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"35.8","Single Cell Type RNA - Horizontal cells [nTPM]":"79.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.9","Single Cell Type RNA - Ionocytes [nTPM]":"89.5","Single Cell Type RNA - Kupffer cells [nTPM]":"42.4","Single Cell Type RNA - Langerhans cells [nTPM]":"15.4","Single Cell Type RNA - Late spermatids [nTPM]":"6.1","Single Cell Type RNA - Leydig cells [nTPM]":"43.2","Single Cell Type RNA - Macrophages [nTPM]":"35.9","Single Cell Type RNA - Melanocytes [nTPM]":"35.6","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"39.8","Single Cell Type RNA - Muller glia cells [nTPM]":"299.7","Single Cell Type RNA - NK-cells [nTPM]":"37.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"70.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"43.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"61.2","Single Cell Type RNA - Paneth cells [nTPM]":"36.7","Single Cell Type RNA - Peritubular cells [nTPM]":"56.1","Single Cell Type RNA - Plasma cells [nTPM]":"27.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"285.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"56.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"97.0","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"29.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"38.7","Single Cell Type RNA - Spermatocytes [nTPM]":"25.8","Single Cell Type RNA - Spermatogonia [nTPM]":"24.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"19.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"63.5","Single Cell Type RNA - T-cells [nTPM]":"29.8","Single Cell Type RNA - Theca cells [nTPM]":"66.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"25.3","Single Cell Type RNA - Urothelial cells [nTPM]":"46.1"},{"Gene":"RDH12","Gene synonym":["FLJ30273","LCA13","RP53","SDR7C2"],"Ensembl":"ENSG00000139988","Gene description":"Retinol dehydrogenase 12","Uniprot":["Q96NR8"],"Chromosome":"14","Position":"67701886-67734451","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Leber congenital amaurosis","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"retina":"222.7","skin 1":"63.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"146.0","Rod photoreceptor cells":"453.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"5.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"4.1","Tissue RNA - amygdala [nTPM]":"1.3","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"1.0","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"2.2","Tissue RNA - cerebellum [nTPM]":"1.0","Tissue RNA - cerebral cortex [nTPM]":"1.4","Tissue RNA - cervix [nTPM]":"11.0","Tissue RNA - choroid plexus [nTPM]":"0.4","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"8.7","Tissue RNA - esophagus [nTPM]":"22.1","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"17.6","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.9","Tissue RNA - hypothalamus [nTPM]":"1.2","Tissue RNA - kidney [nTPM]":"13.6","Tissue RNA - liver [nTPM]":"3.8","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"1.2","Tissue RNA - midbrain [nTPM]":"2.3","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"3.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.9","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"1.2","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"222.7","Tissue RNA - salivary gland [nTPM]":"1.7","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"63.8","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"12.4","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"4.6","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"1.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"1.6","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"23.6","Tissue RNA - white matter [nTPM]":"1.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.3","Brain RNA - basal ganglia [nTPM]":"1.0","Brain RNA - cerebellum [nTPM]":"1.0","Brain RNA - cerebral cortex [nTPM]":"1.4","Brain RNA - hippocampal formation [nTPM]":"0.9","Brain RNA - hypothalamus [nTPM]":"1.2","Brain RNA - medulla oblongata [nTPM]":"1.2","Brain RNA - midbrain [nTPM]":"2.3","Brain RNA - pons [nTPM]":"1.2","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"4.6","Brain RNA - white matter [nTPM]":"1.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"39.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"0.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"146.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.1","Single Cell Type RNA - Endothelial cells [nTPM]":"2.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"5.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.9","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"53.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.5","Single Cell Type RNA - Paneth cells [nTPM]":"2.6","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"453.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"38.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"RDH5","Gene synonym":["HSD17B9","RDH1","SDR9C5"],"Ensembl":"ENSG00000135437","Gene description":"Retinol dehydrogenase 5","Uniprot":["Q92781"],"Chromosome":"12","Position":"55720367-55724705","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid metabolism","Sensory transduction","Steroid metabolism","Vision"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"94.5","liver":"58.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"62.6","Proximal enterocytes":"49.9","Rod photoreceptor cells":"62.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"28.5","ASC TERT1":"24.3","hTEC\/SVTERT24-B":"15.3","hTERT-RPE1":"24.5","LHCN-M2":"15.4","U-87 MG":"26.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063345"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA063345":"AB_2684992"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Tissue RNA - adipose tissue [nTPM]":"94.5","Tissue RNA - adrenal gland [nTPM]":"1.8","Tissue RNA - amygdala [nTPM]":"2.2","Tissue RNA - appendix [nTPM]":"4.1","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"1.0","Tissue RNA - breast [nTPM]":"34.2","Tissue RNA - cerebellum [nTPM]":"2.2","Tissue RNA - cerebral cortex [nTPM]":"2.6","Tissue RNA - cervix [nTPM]":"2.5","Tissue RNA - choroid plexus [nTPM]":"3.5","Tissue RNA - colon [nTPM]":"13.6","Tissue RNA - duodenum [nTPM]":"18.5","Tissue RNA - endometrium 1 [nTPM]":"4.2","Tissue RNA - epididymis [nTPM]":"7.8","Tissue RNA - esophagus [nTPM]":"3.1","Tissue RNA - fallopian tube [nTPM]":"4.6","Tissue RNA - gallbladder [nTPM]":"4.2","Tissue RNA - heart muscle [nTPM]":"9.2","Tissue RNA - hippocampal formation [nTPM]":"2.0","Tissue RNA - hypothalamus [nTPM]":"2.2","Tissue RNA - kidney [nTPM]":"9.0","Tissue RNA - liver [nTPM]":"58.9","Tissue RNA - lung [nTPM]":"1.9","Tissue RNA - lymph node [nTPM]":"1.8","Tissue RNA - medulla oblongata [nTPM]":"2.7","Tissue RNA - midbrain [nTPM]":"2.5","Tissue RNA - ovary [nTPM]":"2.1","Tissue RNA - pancreas [nTPM]":"3.5","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"1.7","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"2.4","Tissue RNA - prostate [nTPM]":"4.4","Tissue RNA - rectum [nTPM]":"4.4","Tissue RNA - retina [nTPM]":"3.2","Tissue RNA - salivary gland [nTPM]":"3.3","Tissue RNA - seminal vesicle [nTPM]":"2.2","Tissue RNA - skeletal muscle [nTPM]":"6.1","Tissue RNA - skin 1 [nTPM]":"2.7","Tissue RNA - small intestine [nTPM]":"15.5","Tissue RNA - smooth muscle [nTPM]":"19.5","Tissue RNA - spinal cord [nTPM]":"2.5","Tissue RNA - spleen [nTPM]":"2.2","Tissue RNA - stomach 1 [nTPM]":"5.9","Tissue RNA - testis [nTPM]":"2.4","Tissue RNA - thalamus [nTPM]":"2.8","Tissue RNA - thymus [nTPM]":"0.9","Tissue RNA - thyroid gland [nTPM]":"2.7","Tissue RNA - tongue [nTPM]":"7.6","Tissue RNA - tonsil [nTPM]":"0.7","Tissue RNA - urinary bladder [nTPM]":"5.5","Tissue RNA - vagina [nTPM]":"2.2","Tissue RNA - white matter [nTPM]":"3.4","Cell RNA - A-431 [nTPM]":"0.7","Cell RNA - A549 [nTPM]":"1.4","Cell RNA - AF22 [nTPM]":"0.8","Cell RNA - AN3-CA [nTPM]":"0.5","Cell RNA - ASC diff [nTPM]":"28.5","Cell RNA - ASC TERT1 [nTPM]":"24.3","Cell RNA - BEWO [nTPM]":"0.6","Cell RNA - BJ [nTPM]":"3.8","Cell RNA - BJ hTERT+ [nTPM]":"4.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.4","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"7.9","Cell RNA - Daudi [nTPM]":"1.0","Cell RNA - EFO-21 [nTPM]":"0.7","Cell RNA - fHDF\/TERT166 [nTPM]":"2.1","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.6","Cell RNA - HDLM-2 [nTPM]":"1.0","Cell RNA - HEK 293 [nTPM]":"1.3","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"2.0","Cell RNA - Hep G2 [nTPM]":"2.1","Cell RNA - HHSteC [nTPM]":"0.8","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"10.5","Cell RNA - hTCEpi [nTPM]":"1.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.3","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"24.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"1.3","Cell RNA - LHCN-M2 [nTPM]":"15.4","Cell RNA - MCF7 [nTPM]":"0.7","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"3.7","Cell RNA - PC-3 [nTPM]":"2.3","Cell RNA - REH [nTPM]":"0.6","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.8","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"1.1","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"3.4","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.7","Cell RNA - THP-1 [nTPM]":"0.6","Cell RNA - TIME [nTPM]":"0.5","Cell RNA - U-138 MG [nTPM]":"1.5","Cell RNA - U-2 OS [nTPM]":"1.5","Cell RNA - U-2197 [nTPM]":"1.1","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"1.1","Cell RNA - U-266\/84 [nTPM]":"0.5","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"26.7","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.2","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"2.2","Brain RNA - cerebral cortex [nTPM]":"2.6","Brain RNA - hippocampal formation [nTPM]":"2.0","Brain RNA - hypothalamus [nTPM]":"2.2","Brain RNA - medulla oblongata [nTPM]":"2.7","Brain RNA - midbrain [nTPM]":"2.5","Brain RNA - pons [nTPM]":"2.4","Brain RNA - spinal cord [nTPM]":"2.5","Brain RNA - thalamus [nTPM]":"2.8","Brain RNA - white matter [nTPM]":"3.4","Single Cell Type RNA - Adipocytes [nTPM]":"2.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"4.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"24.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"2.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"62.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.2","Single Cell Type RNA - dendritic cells [nTPM]":"5.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.9","Single Cell Type RNA - Endothelial cells [nTPM]":"3.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.5","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.2","Single Cell Type RNA - Fibroblasts [nTPM]":"3.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"4.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"18.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.5","Single Cell Type RNA - Langerhans cells [nTPM]":"7.9","Single Cell Type RNA - Late spermatids [nTPM]":"2.3","Single Cell Type RNA - Leydig cells [nTPM]":"13.4","Single Cell Type RNA - Macrophages [nTPM]":"2.3","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"4.7","Single Cell Type RNA - Muller glia cells [nTPM]":"8.2","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.6","Single Cell Type RNA - Paneth cells [nTPM]":"18.6","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"0.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"49.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"62.9","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.3","Single Cell Type RNA - Spermatocytes [nTPM]":"3.9","Single Cell Type RNA - Spermatogonia [nTPM]":"6.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - T-cells [nTPM]":"4.8","Single Cell Type RNA - Theca cells [nTPM]":"5.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.9","Single Cell Type RNA - Urothelial cells [nTPM]":"3.1"},{"Gene":"RECQL4","Gene synonym":["RecQ4"],"Ensembl":"ENSG00000160957","Gene description":"RecQ like helicase 4","Uniprot":["O94761"],"Chromosome":"8","Position":"144511288-144517845","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Helicase","Hydrolase"],"Disease involvement":["Cancer-related genes","Cataract","Craniosynostosis","Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"25.4","testis":"22.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"23.5","Spermatogonia":"20.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017800","HPA025821"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB017800":null,"HPA025821":"AB_1856168"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.91e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.7","Tissue RNA - adrenal gland [nTPM]":"1.8","Tissue RNA - amygdala [nTPM]":"3.0","Tissue RNA - appendix [nTPM]":"5.8","Tissue RNA - basal ganglia [nTPM]":"3.7","Tissue RNA - bone marrow [nTPM]":"25.4","Tissue RNA - breast [nTPM]":"2.0","Tissue RNA - cerebellum [nTPM]":"7.7","Tissue RNA - cerebral cortex [nTPM]":"7.0","Tissue RNA - cervix [nTPM]":"2.9","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"4.7","Tissue RNA - duodenum [nTPM]":"6.0","Tissue RNA - endometrium 1 [nTPM]":"2.5","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"13.3","Tissue RNA - fallopian tube [nTPM]":"2.1","Tissue RNA - gallbladder [nTPM]":"2.1","Tissue RNA - heart muscle [nTPM]":"1.8","Tissue RNA - hippocampal formation [nTPM]":"2.6","Tissue RNA - hypothalamus [nTPM]":"1.6","Tissue RNA - kidney [nTPM]":"2.5","Tissue RNA - liver [nTPM]":"2.7","Tissue RNA - lung [nTPM]":"2.3","Tissue RNA - lymph node [nTPM]":"6.8","Tissue RNA - medulla oblongata [nTPM]":"6.9","Tissue RNA - midbrain [nTPM]":"2.3","Tissue RNA - ovary [nTPM]":"2.7","Tissue RNA - pancreas [nTPM]":"3.1","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"3.1","Tissue RNA - placenta [nTPM]":"2.5","Tissue RNA - pons [nTPM]":"7.4","Tissue RNA - prostate [nTPM]":"8.6","Tissue RNA - rectum [nTPM]":"1.6","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"5.8","Tissue RNA - seminal vesicle [nTPM]":"0.8","Tissue RNA - skeletal muscle [nTPM]":"2.5","Tissue RNA - skin 1 [nTPM]":"10.1","Tissue RNA - small intestine [nTPM]":"5.2","Tissue RNA - smooth muscle [nTPM]":"1.0","Tissue RNA - spinal cord [nTPM]":"1.7","Tissue RNA - spleen [nTPM]":"6.5","Tissue RNA - stomach 1 [nTPM]":"3.2","Tissue RNA - testis [nTPM]":"22.4","Tissue RNA - thalamus [nTPM]":"4.1","Tissue RNA - thymus [nTPM]":"7.4","Tissue RNA - thyroid gland [nTPM]":"3.4","Tissue RNA - tongue [nTPM]":"0.5","Tissue RNA - tonsil [nTPM]":"2.5","Tissue RNA - urinary bladder [nTPM]":"2.5","Tissue RNA - vagina [nTPM]":"3.1","Tissue RNA - white matter [nTPM]":"3.6","Cell RNA - A-431 [nTPM]":"33.7","Cell RNA - A549 [nTPM]":"58.8","Cell RNA - AF22 [nTPM]":"27.0","Cell RNA - AN3-CA [nTPM]":"57.1","Cell RNA - ASC diff [nTPM]":"1.6","Cell RNA - ASC TERT1 [nTPM]":"2.6","Cell RNA - BEWO [nTPM]":"47.1","Cell RNA - BJ [nTPM]":"33.2","Cell RNA - BJ hTERT+ [nTPM]":"5.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.2","Cell RNA - CACO-2 [nTPM]":"58.4","Cell RNA - CAPAN-2 [nTPM]":"48.4","Cell RNA - Daudi [nTPM]":"22.8","Cell RNA - EFO-21 [nTPM]":"21.5","Cell RNA - fHDF\/TERT166 [nTPM]":"5.6","Cell RNA - GAMG [nTPM]":"14.2","Cell RNA - HaCaT [nTPM]":"40.1","Cell RNA - HAP1 [nTPM]":"18.0","Cell RNA - HBEC3-KT [nTPM]":"14.2","Cell RNA - HBF TERT88 [nTPM]":"6.6","Cell RNA - HDLM-2 [nTPM]":"40.3","Cell RNA - HEK 293 [nTPM]":"68.6","Cell RNA - HEL [nTPM]":"82.4","Cell RNA - HeLa [nTPM]":"118.5","Cell RNA - Hep G2 [nTPM]":"44.3","Cell RNA - HHSteC [nTPM]":"0.5","Cell RNA - HL-60 [nTPM]":"21.2","Cell RNA - HMC-1 [nTPM]":"65.7","Cell RNA - HSkMC [nTPM]":"3.3","Cell RNA - hTCEpi [nTPM]":"2.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"27.1","Cell RNA - hTERT-HME1 [nTPM]":"5.5","Cell RNA - hTERT-RPE1 [nTPM]":"3.4","Cell RNA - HUVEC TERT2 [nTPM]":"6.8","Cell RNA - JURKAT [nTPM]":"45.4","Cell RNA - K-562 [nTPM]":"83.3","Cell RNA - Karpas-707 [nTPM]":"28.9","Cell RNA - LHCN-M2 [nTPM]":"8.5","Cell RNA - MCF7 [nTPM]":"104.1","Cell RNA - MOLT-4 [nTPM]":"77.3","Cell RNA - NB-4 [nTPM]":"56.9","Cell RNA - NTERA-2 [nTPM]":"18.8","Cell RNA - OE19 [nTPM]":"27.8","Cell RNA - PC-3 [nTPM]":"69.5","Cell RNA - REH [nTPM]":"80.0","Cell RNA - RH-30 [nTPM]":"21.2","Cell RNA - RPMI-8226 [nTPM]":"37.9","Cell RNA - RPTEC TERT1 [nTPM]":"6.7","Cell RNA - RT4 [nTPM]":"35.8","Cell RNA - SCLC-21H [nTPM]":"52.9","Cell RNA - SH-SY5Y [nTPM]":"32.0","Cell RNA - SiHa [nTPM]":"45.2","Cell RNA - SK-BR-3 [nTPM]":"37.3","Cell RNA - SK-MEL-30 [nTPM]":"12.1","Cell RNA - SuSa [nTPM]":"7.4","Cell RNA - T-47d [nTPM]":"45.5","Cell RNA - THP-1 [nTPM]":"45.7","Cell RNA - TIME [nTPM]":"9.2","Cell RNA - U-138 MG [nTPM]":"38.9","Cell RNA - U-2 OS [nTPM]":"117.4","Cell RNA - U-2197 [nTPM]":"47.3","Cell RNA - U-251 MG [nTPM]":"62.6","Cell RNA - U-266\/70 [nTPM]":"16.0","Cell RNA - U-266\/84 [nTPM]":"18.1","Cell RNA - U-698 [nTPM]":"39.3","Cell RNA - U-87 MG [nTPM]":"22.4","Cell RNA - U-937 [nTPM]":"64.6","Cell RNA - WM-115 [nTPM]":"39.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.0","Brain RNA - basal ganglia [nTPM]":"3.7","Brain RNA - cerebellum [nTPM]":"7.7","Brain RNA - cerebral cortex [nTPM]":"7.0","Brain RNA - hippocampal formation [nTPM]":"2.6","Brain RNA - hypothalamus [nTPM]":"1.6","Brain RNA - medulla oblongata [nTPM]":"6.9","Brain RNA - midbrain [nTPM]":"2.3","Brain RNA - pons [nTPM]":"7.4","Brain RNA - spinal cord [nTPM]":"1.7","Brain RNA - thalamus [nTPM]":"4.1","Brain RNA - white matter [nTPM]":"3.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"2.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"2.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.9","Single Cell Type RNA - dendritic cells [nTPM]":"1.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.5","Single Cell Type RNA - Early spermatids [nTPM]":"3.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.9","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"6.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"8.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"1.1","Single Cell Type RNA - Late spermatids [nTPM]":"7.4","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.2","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"9.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"23.5","Single Cell Type RNA - Spermatogonia [nTPM]":"20.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - T-cells [nTPM]":"1.2","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"RETREG1","Gene synonym":["FAM134B","FLJ20152","JK1"],"Ensembl":"ENSG00000154153","Gene description":"Reticulophagy regulator 1","Uniprot":["Q9H6L5"],"Chromosome":"5","Position":"16473038-16617038","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Autophagy"],"Molecular function":null,"Disease involvement":["Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"91.4","skeletal muscle":"141.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"73.7","Cytotrophoblasts":"53.7","Exocrine glandular cells":"59.3","Glandular and luminal cells":"197.7","Pancreatic endocrine cells":"51.5","Proximal tubular cells":"152.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"28.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"2.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"2.3","T-cells":"1.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"26.0","GAMG":"20.3","HSkMC":"28.8","MOLT-4":"20.4","RPTEC TERT1":"26.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012077"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA012077":"AB_2668621"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.25e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Tissue RNA - adipose tissue [nTPM]":"15.6","Tissue RNA - adrenal gland [nTPM]":"3.5","Tissue RNA - amygdala [nTPM]":"20.6","Tissue RNA - appendix [nTPM]":"6.6","Tissue RNA - basal ganglia [nTPM]":"26.4","Tissue RNA - bone marrow [nTPM]":"2.0","Tissue RNA - breast [nTPM]":"13.6","Tissue RNA - cerebellum [nTPM]":"23.9","Tissue RNA - cerebral cortex [nTPM]":"33.2","Tissue RNA - cervix [nTPM]":"13.2","Tissue RNA - choroid plexus [nTPM]":"21.6","Tissue RNA - colon [nTPM]":"24.6","Tissue RNA - duodenum [nTPM]":"12.6","Tissue RNA - endometrium 1 [nTPM]":"4.0","Tissue RNA - epididymis [nTPM]":"5.2","Tissue RNA - esophagus [nTPM]":"3.6","Tissue RNA - fallopian tube [nTPM]":"7.5","Tissue RNA - gallbladder [nTPM]":"13.4","Tissue RNA - heart muscle [nTPM]":"91.4","Tissue RNA - hippocampal formation [nTPM]":"19.4","Tissue RNA - hypothalamus [nTPM]":"22.1","Tissue RNA - kidney [nTPM]":"61.0","Tissue RNA - liver [nTPM]":"44.2","Tissue RNA - lung [nTPM]":"9.3","Tissue RNA - lymph node [nTPM]":"6.4","Tissue RNA - medulla oblongata [nTPM]":"27.2","Tissue RNA - midbrain [nTPM]":"25.2","Tissue RNA - ovary [nTPM]":"2.1","Tissue RNA - pancreas [nTPM]":"37.7","Tissue RNA - parathyroid gland [nTPM]":"30.1","Tissue RNA - pituitary gland [nTPM]":"9.9","Tissue RNA - placenta [nTPM]":"13.2","Tissue RNA - pons [nTPM]":"27.8","Tissue RNA - prostate [nTPM]":"11.1","Tissue RNA - rectum [nTPM]":"32.4","Tissue RNA - retina [nTPM]":"7.5","Tissue RNA - salivary gland [nTPM]":"5.2","Tissue RNA - seminal vesicle [nTPM]":"5.0","Tissue RNA - skeletal muscle [nTPM]":"141.8","Tissue RNA - skin 1 [nTPM]":"10.0","Tissue RNA - small intestine [nTPM]":"25.6","Tissue RNA - smooth muscle [nTPM]":"2.6","Tissue RNA - spinal cord [nTPM]":"23.6","Tissue RNA - spleen [nTPM]":"2.3","Tissue RNA - stomach 1 [nTPM]":"10.9","Tissue RNA - testis [nTPM]":"12.3","Tissue RNA - thalamus [nTPM]":"25.0","Tissue RNA - thymus [nTPM]":"20.6","Tissue RNA - thyroid gland [nTPM]":"6.7","Tissue RNA - tongue [nTPM]":"81.9","Tissue RNA - tonsil [nTPM]":"4.3","Tissue RNA - urinary bladder [nTPM]":"2.3","Tissue RNA - vagina [nTPM]":"5.2","Tissue RNA - white matter [nTPM]":"37.6","Cell RNA - A-431 [nTPM]":"1.3","Cell RNA - A549 [nTPM]":"0.5","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"3.5","Cell RNA - ASC diff [nTPM]":"26.0","Cell RNA - ASC TERT1 [nTPM]":"3.2","Cell RNA - BEWO [nTPM]":"15.1","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"3.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.1","Cell RNA - CACO-2 [nTPM]":"2.3","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"2.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"20.3","Cell RNA - HaCaT [nTPM]":"3.9","Cell RNA - HAP1 [nTPM]":"7.8","Cell RNA - HBEC3-KT [nTPM]":"0.8","Cell RNA - HBF TERT88 [nTPM]":"1.0","Cell RNA - HDLM-2 [nTPM]":"4.1","Cell RNA - HEK 293 [nTPM]":"3.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"10.6","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"5.3","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"28.8","Cell RNA - hTCEpi [nTPM]":"11.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.6","Cell RNA - hTERT-HME1 [nTPM]":"3.1","Cell RNA - hTERT-RPE1 [nTPM]":"7.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"15.4","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"1.2","Cell RNA - MCF7 [nTPM]":"1.0","Cell RNA - MOLT-4 [nTPM]":"20.4","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"3.4","Cell RNA - PC-3 [nTPM]":"0.6","Cell RNA - REH [nTPM]":"3.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.2","Cell RNA - RPTEC TERT1 [nTPM]":"26.2","Cell RNA - RT4 [nTPM]":"0.9","Cell RNA - SCLC-21H [nTPM]":"17.4","Cell RNA - SH-SY5Y [nTPM]":"2.0","Cell RNA - SiHa [nTPM]":"1.0","Cell RNA - SK-BR-3 [nTPM]":"1.1","Cell RNA - SK-MEL-30 [nTPM]":"13.1","Cell RNA - SuSa [nTPM]":"1.9","Cell RNA - T-47d [nTPM]":"5.9","Cell RNA - THP-1 [nTPM]":"2.4","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"2.4","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"6.4","Cell RNA - U-251 MG [nTPM]":"3.1","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"14.9","Cell RNA - U-937 [nTPM]":"18.0","Cell RNA - WM-115 [nTPM]":"6.5","Blood RNA - basophil [nTPM]":"2.3","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.0","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"20.6","Brain RNA - basal ganglia [nTPM]":"26.4","Brain RNA - cerebellum [nTPM]":"23.9","Brain RNA - cerebral cortex [nTPM]":"33.2","Brain RNA - hippocampal formation [nTPM]":"19.4","Brain RNA - hypothalamus [nTPM]":"22.1","Brain RNA - medulla oblongata [nTPM]":"27.2","Brain RNA - midbrain [nTPM]":"25.2","Brain RNA - pons [nTPM]":"27.8","Brain RNA - spinal cord [nTPM]":"23.6","Brain RNA - thalamus [nTPM]":"25.0","Brain RNA - white matter [nTPM]":"37.6","Single Cell Type RNA - Adipocytes [nTPM]":"4.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"73.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"3.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"33.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"19.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"9.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"53.7","Single Cell Type RNA - dendritic cells [nTPM]":"2.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"31.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"33.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"45.2","Single Cell Type RNA - Endothelial cells [nTPM]":"1.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"59.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.0","Single Cell Type RNA - Fibroblasts [nTPM]":"7.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"197.7","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"3.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"5.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"51.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"152.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.9","Single Cell Type RNA - T-cells [nTPM]":"8.1","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"RFT1","Gene synonym":["CDG1N"],"Ensembl":"ENSG00000163933","Gene description":"RFT1 homolog","Uniprot":["Q96AA3"],"Chromosome":"3","Position":"53088483-53130453","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"39.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060327","HPA069022"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA060327":"AB_2684253","HPA069022":"AB_2732126"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.69e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.8","Tissue RNA - adrenal gland [nTPM]":"12.5","Tissue RNA - amygdala [nTPM]":"5.7","Tissue RNA - appendix [nTPM]":"14.5","Tissue RNA - basal ganglia [nTPM]":"6.2","Tissue RNA - bone marrow [nTPM]":"8.3","Tissue RNA - breast [nTPM]":"12.5","Tissue RNA - cerebellum [nTPM]":"5.5","Tissue RNA - cerebral cortex [nTPM]":"6.6","Tissue RNA - cervix [nTPM]":"9.0","Tissue RNA - choroid plexus [nTPM]":"4.9","Tissue RNA - colon [nTPM]":"11.8","Tissue RNA - duodenum [nTPM]":"10.3","Tissue RNA - endometrium 1 [nTPM]":"9.1","Tissue RNA - epididymis [nTPM]":"13.0","Tissue RNA - esophagus [nTPM]":"12.1","Tissue RNA - fallopian tube [nTPM]":"12.4","Tissue RNA - gallbladder [nTPM]":"10.5","Tissue RNA - heart muscle [nTPM]":"9.0","Tissue RNA - hippocampal formation [nTPM]":"6.1","Tissue RNA - hypothalamus [nTPM]":"5.3","Tissue RNA - kidney [nTPM]":"8.7","Tissue RNA - liver [nTPM]":"14.0","Tissue RNA - lung [nTPM]":"9.2","Tissue RNA - lymph node [nTPM]":"16.7","Tissue RNA - medulla oblongata [nTPM]":"5.6","Tissue RNA - midbrain [nTPM]":"5.2","Tissue RNA - ovary [nTPM]":"12.5","Tissue RNA - pancreas [nTPM]":"22.3","Tissue RNA - parathyroid gland [nTPM]":"15.6","Tissue RNA - pituitary gland [nTPM]":"6.2","Tissue RNA - placenta [nTPM]":"13.8","Tissue RNA - pons [nTPM]":"5.9","Tissue RNA - prostate [nTPM]":"9.3","Tissue RNA - rectum [nTPM]":"13.2","Tissue RNA - retina [nTPM]":"4.3","Tissue RNA - salivary gland [nTPM]":"18.0","Tissue RNA - seminal vesicle [nTPM]":"10.4","Tissue RNA - skeletal muscle [nTPM]":"5.1","Tissue RNA - skin 1 [nTPM]":"9.9","Tissue RNA - small intestine [nTPM]":"10.5","Tissue RNA - smooth muscle [nTPM]":"11.2","Tissue RNA - spinal cord [nTPM]":"5.5","Tissue RNA - spleen [nTPM]":"9.9","Tissue RNA - stomach 1 [nTPM]":"10.4","Tissue RNA - testis [nTPM]":"13.5","Tissue RNA - thalamus [nTPM]":"5.4","Tissue RNA - thymus [nTPM]":"14.2","Tissue RNA - thyroid gland [nTPM]":"14.6","Tissue RNA - tongue [nTPM]":"6.7","Tissue RNA - tonsil [nTPM]":"15.8","Tissue RNA - urinary bladder [nTPM]":"12.6","Tissue RNA - vagina [nTPM]":"8.8","Tissue RNA - white matter [nTPM]":"8.0","Cell RNA - A-431 [nTPM]":"39.1","Cell RNA - A549 [nTPM]":"36.3","Cell RNA - AF22 [nTPM]":"24.3","Cell RNA - AN3-CA [nTPM]":"39.0","Cell RNA - ASC diff [nTPM]":"27.9","Cell RNA - ASC TERT1 [nTPM]":"29.5","Cell RNA - BEWO [nTPM]":"50.6","Cell RNA - BJ [nTPM]":"34.8","Cell RNA - BJ hTERT+ [nTPM]":"32.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"59.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"53.7","Cell RNA - CACO-2 [nTPM]":"35.9","Cell RNA - CAPAN-2 [nTPM]":"74.6","Cell RNA - Daudi [nTPM]":"51.0","Cell RNA - EFO-21 [nTPM]":"21.3","Cell RNA - fHDF\/TERT166 [nTPM]":"33.5","Cell RNA - GAMG [nTPM]":"55.6","Cell RNA - HaCaT [nTPM]":"40.7","Cell RNA - HAP1 [nTPM]":"55.4","Cell RNA - HBEC3-KT [nTPM]":"56.8","Cell RNA - HBF TERT88 [nTPM]":"51.9","Cell RNA - HDLM-2 [nTPM]":"48.4","Cell RNA - HEK 293 [nTPM]":"24.5","Cell RNA - HEL [nTPM]":"50.6","Cell RNA - HeLa [nTPM]":"24.8","Cell RNA - Hep G2 [nTPM]":"36.0","Cell RNA - HHSteC [nTPM]":"48.8","Cell RNA - HL-60 [nTPM]":"46.7","Cell RNA - HMC-1 [nTPM]":"28.4","Cell RNA - HSkMC [nTPM]":"31.4","Cell RNA - hTCEpi [nTPM]":"46.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"79.6","Cell RNA - hTERT-HME1 [nTPM]":"57.1","Cell RNA - hTERT-RPE1 [nTPM]":"26.2","Cell RNA - HUVEC TERT2 [nTPM]":"37.9","Cell RNA - JURKAT [nTPM]":"52.7","Cell RNA - K-562 [nTPM]":"27.1","Cell RNA - Karpas-707 [nTPM]":"45.2","Cell RNA - LHCN-M2 [nTPM]":"39.4","Cell RNA - MCF7 [nTPM]":"39.6","Cell RNA - MOLT-4 [nTPM]":"44.2","Cell RNA - NB-4 [nTPM]":"27.3","Cell RNA - NTERA-2 [nTPM]":"48.8","Cell RNA - OE19 [nTPM]":"67.5","Cell RNA - PC-3 [nTPM]":"47.3","Cell RNA - REH [nTPM]":"18.1","Cell RNA - RH-30 [nTPM]":"23.5","Cell RNA - RPMI-8226 [nTPM]":"77.5","Cell RNA - RPTEC TERT1 [nTPM]":"32.8","Cell RNA - RT4 [nTPM]":"26.1","Cell RNA - SCLC-21H [nTPM]":"13.8","Cell RNA - SH-SY5Y [nTPM]":"18.7","Cell RNA - SiHa [nTPM]":"43.0","Cell RNA - SK-BR-3 [nTPM]":"30.9","Cell RNA - SK-MEL-30 [nTPM]":"31.2","Cell RNA - SuSa [nTPM]":"26.2","Cell RNA - T-47d [nTPM]":"23.3","Cell RNA - THP-1 [nTPM]":"65.5","Cell RNA - TIME [nTPM]":"25.5","Cell RNA - U-138 MG [nTPM]":"54.3","Cell RNA - U-2 OS [nTPM]":"35.2","Cell RNA - U-2197 [nTPM]":"37.7","Cell RNA - U-251 MG [nTPM]":"69.1","Cell RNA - U-266\/70 [nTPM]":"28.6","Cell RNA - U-266\/84 [nTPM]":"37.1","Cell RNA - U-698 [nTPM]":"38.4","Cell RNA - U-87 MG [nTPM]":"38.9","Cell RNA - U-937 [nTPM]":"58.8","Cell RNA - WM-115 [nTPM]":"58.3","Blood RNA - basophil [nTPM]":"50.2","Blood RNA - classical monocyte [nTPM]":"40.2","Blood RNA - eosinophil [nTPM]":"18.4","Blood RNA - gdT-cell [nTPM]":"22.2","Blood RNA - intermediate monocyte [nTPM]":"40.5","Blood RNA - MAIT T-cell [nTPM]":"22.5","Blood RNA - memory B-cell [nTPM]":"21.2","Blood RNA - memory CD4 T-cell [nTPM]":"20.6","Blood RNA - memory CD8 T-cell [nTPM]":"22.9","Blood RNA - myeloid DC [nTPM]":"42.9","Blood RNA - naive B-cell [nTPM]":"35.5","Blood RNA - naive CD4 T-cell [nTPM]":"23.7","Blood RNA - naive CD8 T-cell [nTPM]":"23.7","Blood RNA - neutrophil [nTPM]":"13.4","Blood RNA - NK-cell [nTPM]":"23.1","Blood RNA - non-classical monocyte [nTPM]":"29.4","Blood RNA - plasmacytoid DC [nTPM]":"48.9","Blood RNA - T-reg [nTPM]":"20.1","Blood RNA - total PBMC [nTPM]":"25.7","Brain RNA - amygdala [nTPM]":"5.7","Brain RNA - basal ganglia [nTPM]":"6.2","Brain RNA - cerebellum [nTPM]":"5.5","Brain RNA - cerebral cortex [nTPM]":"6.6","Brain RNA - hippocampal formation [nTPM]":"6.1","Brain RNA - hypothalamus [nTPM]":"5.3","Brain RNA - medulla oblongata [nTPM]":"5.6","Brain RNA - midbrain [nTPM]":"5.2","Brain RNA - pons [nTPM]":"5.9","Brain RNA - spinal cord [nTPM]":"5.5","Brain RNA - thalamus [nTPM]":"5.4","Brain RNA - white matter [nTPM]":"8.0","Single Cell Type RNA - Adipocytes [nTPM]":"6.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.7","Single Cell Type RNA - Astrocytes [nTPM]":"8.8","Single Cell Type RNA - B-cells [nTPM]":"8.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"4.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"12.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"39.4","Single Cell Type RNA - dendritic cells [nTPM]":"6.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"17.4","Single Cell Type RNA - Early spermatids [nTPM]":"1.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.5","Single Cell Type RNA - Endothelial cells [nTPM]":"8.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"17.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"33.1","Single Cell Type RNA - Fibroblasts [nTPM]":"9.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.7","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"17.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.4","Single Cell Type RNA - Hepatocytes [nTPM]":"10.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.0","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.4","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"9.9","Single Cell Type RNA - Langerhans cells [nTPM]":"5.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.3","Single Cell Type RNA - Leydig cells [nTPM]":"8.7","Single Cell Type RNA - Macrophages [nTPM]":"9.8","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"11.7","Single Cell Type RNA - Muller glia cells [nTPM]":"5.8","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.2","Single Cell Type RNA - Paneth cells [nTPM]":"8.8","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"19.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.7","Single Cell Type RNA - Spermatocytes [nTPM]":"10.1","Single Cell Type RNA - Spermatogonia [nTPM]":"8.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"24.2","Single Cell Type RNA - T-cells [nTPM]":"7.7","Single Cell Type RNA - Theca cells [nTPM]":"22.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.7","Single Cell Type RNA - Urothelial cells [nTPM]":"8.1"},{"Gene":"RFWD3","Gene synonym":["FANCW","FLJ10520","RNF201"],"Ensembl":"ENSG00000168411","Gene description":"Ring finger and WD repeat domain 3","Uniprot":["Q6PCD5"],"Chromosome":"16","Position":"74621399-74666877","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Fanconi anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"47.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"48.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048258","HPA075649"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA048258":"AB_2680332","HPA075649":"AB_2686761"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.2","Tissue RNA - adrenal gland [nTPM]":"3.9","Tissue RNA - amygdala [nTPM]":"2.5","Tissue RNA - appendix [nTPM]":"9.9","Tissue RNA - basal ganglia [nTPM]":"3.5","Tissue RNA - bone marrow [nTPM]":"47.7","Tissue RNA - breast [nTPM]":"7.6","Tissue RNA - cerebellum [nTPM]":"4.0","Tissue RNA - cerebral cortex [nTPM]":"3.2","Tissue RNA - cervix [nTPM]":"6.4","Tissue RNA - choroid plexus [nTPM]":"4.4","Tissue RNA - colon [nTPM]":"8.0","Tissue RNA - duodenum [nTPM]":"6.5","Tissue RNA - endometrium 1 [nTPM]":"6.2","Tissue RNA - epididymis [nTPM]":"5.3","Tissue RNA - esophagus [nTPM]":"9.4","Tissue RNA - fallopian tube [nTPM]":"6.8","Tissue RNA - gallbladder [nTPM]":"6.5","Tissue RNA - heart muscle [nTPM]":"2.9","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"2.9","Tissue RNA - kidney [nTPM]":"6.7","Tissue RNA - liver [nTPM]":"5.8","Tissue RNA - lung [nTPM]":"6.1","Tissue RNA - lymph node [nTPM]":"15.4","Tissue RNA - medulla oblongata [nTPM]":"3.3","Tissue RNA - midbrain [nTPM]":"3.1","Tissue RNA - ovary [nTPM]":"7.0","Tissue RNA - pancreas [nTPM]":"10.2","Tissue RNA - parathyroid gland [nTPM]":"6.8","Tissue RNA - pituitary gland [nTPM]":"3.8","Tissue RNA - placenta [nTPM]":"8.0","Tissue RNA - pons [nTPM]":"3.2","Tissue RNA - prostate [nTPM]":"4.9","Tissue RNA - rectum [nTPM]":"9.3","Tissue RNA - retina [nTPM]":"6.2","Tissue RNA - salivary gland [nTPM]":"5.8","Tissue RNA - seminal vesicle [nTPM]":"5.1","Tissue RNA - skeletal muscle [nTPM]":"3.3","Tissue RNA - skin 1 [nTPM]":"12.6","Tissue RNA - small intestine [nTPM]":"6.1","Tissue RNA - smooth muscle [nTPM]":"6.1","Tissue RNA - spinal cord [nTPM]":"2.8","Tissue RNA - spleen [nTPM]":"8.1","Tissue RNA - stomach 1 [nTPM]":"6.2","Tissue RNA - testis [nTPM]":"25.2","Tissue RNA - thalamus [nTPM]":"3.4","Tissue RNA - thymus [nTPM]":"27.1","Tissue RNA - thyroid gland [nTPM]":"6.6","Tissue RNA - tongue [nTPM]":"2.7","Tissue RNA - tonsil [nTPM]":"16.7","Tissue RNA - urinary bladder [nTPM]":"7.2","Tissue RNA - vagina [nTPM]":"6.8","Tissue RNA - white matter [nTPM]":"4.7","Cell RNA - A-431 [nTPM]":"46.1","Cell RNA - A549 [nTPM]":"57.5","Cell RNA - AF22 [nTPM]":"42.6","Cell RNA - AN3-CA [nTPM]":"31.2","Cell RNA - ASC diff [nTPM]":"8.8","Cell RNA - ASC TERT1 [nTPM]":"11.9","Cell RNA - BEWO [nTPM]":"47.8","Cell RNA - BJ [nTPM]":"40.5","Cell RNA - BJ hTERT+ [nTPM]":"30.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"63.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"54.5","Cell RNA - CACO-2 [nTPM]":"75.4","Cell RNA - CAPAN-2 [nTPM]":"46.8","Cell RNA - Daudi [nTPM]":"63.6","Cell RNA - EFO-21 [nTPM]":"32.1","Cell RNA - fHDF\/TERT166 [nTPM]":"31.8","Cell RNA - GAMG [nTPM]":"31.6","Cell RNA - HaCaT [nTPM]":"53.9","Cell RNA - HAP1 [nTPM]":"70.3","Cell RNA - HBEC3-KT [nTPM]":"42.1","Cell RNA - HBF TERT88 [nTPM]":"76.9","Cell RNA - HDLM-2 [nTPM]":"20.0","Cell RNA - HEK 293 [nTPM]":"42.1","Cell RNA - HEL [nTPM]":"56.3","Cell RNA - HeLa [nTPM]":"46.0","Cell RNA - Hep G2 [nTPM]":"43.0","Cell RNA - HHSteC [nTPM]":"7.6","Cell RNA - HL-60 [nTPM]":"57.3","Cell RNA - HMC-1 [nTPM]":"56.3","Cell RNA - HSkMC [nTPM]":"8.6","Cell RNA - hTCEpi [nTPM]":"13.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"79.6","Cell RNA - hTERT-HME1 [nTPM]":"48.7","Cell RNA - hTERT-RPE1 [nTPM]":"16.3","Cell RNA - HUVEC TERT2 [nTPM]":"27.3","Cell RNA - JURKAT [nTPM]":"53.2","Cell RNA - K-562 [nTPM]":"86.7","Cell RNA - Karpas-707 [nTPM]":"27.7","Cell RNA - LHCN-M2 [nTPM]":"48.1","Cell RNA - MCF7 [nTPM]":"72.8","Cell RNA - MOLT-4 [nTPM]":"84.0","Cell RNA - NB-4 [nTPM]":"52.2","Cell RNA - NTERA-2 [nTPM]":"84.0","Cell RNA - OE19 [nTPM]":"26.8","Cell RNA - PC-3 [nTPM]":"27.7","Cell RNA - REH [nTPM]":"128.7","Cell RNA - RH-30 [nTPM]":"28.8","Cell RNA - RPMI-8226 [nTPM]":"55.9","Cell RNA - RPTEC TERT1 [nTPM]":"22.7","Cell RNA - RT4 [nTPM]":"47.8","Cell RNA - SCLC-21H [nTPM]":"31.5","Cell RNA - SH-SY5Y [nTPM]":"33.6","Cell RNA - SiHa [nTPM]":"65.2","Cell RNA - SK-BR-3 [nTPM]":"22.8","Cell RNA - SK-MEL-30 [nTPM]":"28.8","Cell RNA - SuSa [nTPM]":"38.2","Cell RNA - T-47d [nTPM]":"41.7","Cell RNA - THP-1 [nTPM]":"48.4","Cell RNA - TIME [nTPM]":"26.7","Cell RNA - U-138 MG [nTPM]":"46.0","Cell RNA - U-2 OS [nTPM]":"43.9","Cell RNA - U-2197 [nTPM]":"26.2","Cell RNA - U-251 MG [nTPM]":"51.4","Cell RNA - U-266\/70 [nTPM]":"37.4","Cell RNA - U-266\/84 [nTPM]":"75.1","Cell RNA - U-698 [nTPM]":"188.3","Cell RNA - U-87 MG [nTPM]":"32.8","Cell RNA - U-937 [nTPM]":"43.5","Cell RNA - WM-115 [nTPM]":"57.0","Blood RNA - basophil [nTPM]":"12.1","Blood RNA - classical monocyte [nTPM]":"4.4","Blood RNA - eosinophil [nTPM]":"6.5","Blood RNA - gdT-cell [nTPM]":"5.5","Blood RNA - intermediate monocyte [nTPM]":"4.1","Blood RNA - MAIT T-cell [nTPM]":"6.1","Blood RNA - memory B-cell [nTPM]":"4.9","Blood RNA - memory CD4 T-cell [nTPM]":"4.5","Blood RNA - memory CD8 T-cell [nTPM]":"5.1","Blood RNA - myeloid DC [nTPM]":"4.6","Blood RNA - naive B-cell [nTPM]":"5.4","Blood RNA - naive CD4 T-cell [nTPM]":"6.7","Blood RNA - naive CD8 T-cell [nTPM]":"4.8","Blood RNA - neutrophil [nTPM]":"4.9","Blood RNA - NK-cell [nTPM]":"6.2","Blood RNA - non-classical monocyte [nTPM]":"7.7","Blood RNA - plasmacytoid DC [nTPM]":"3.5","Blood RNA - T-reg [nTPM]":"7.2","Blood RNA - total PBMC [nTPM]":"4.4","Brain RNA - amygdala [nTPM]":"2.5","Brain RNA - basal ganglia [nTPM]":"3.5","Brain RNA - cerebellum [nTPM]":"4.0","Brain RNA - cerebral cortex [nTPM]":"3.2","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"2.9","Brain RNA - medulla oblongata [nTPM]":"3.3","Brain RNA - midbrain [nTPM]":"3.1","Brain RNA - pons [nTPM]":"3.2","Brain RNA - spinal cord [nTPM]":"2.8","Brain RNA - thalamus [nTPM]":"3.4","Brain RNA - white matter [nTPM]":"4.7","Single Cell Type RNA - Adipocytes [nTPM]":"6.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.9","Single Cell Type RNA - Astrocytes [nTPM]":"4.2","Single Cell Type RNA - B-cells [nTPM]":"13.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"6.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"5.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.1","Single Cell Type RNA - dendritic cells [nTPM]":"15.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"6.2","Single Cell Type RNA - Early spermatids [nTPM]":"5.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.7","Single Cell Type RNA - Endothelial cells [nTPM]":"7.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.5","Single Cell Type RNA - Erythroid cells [nTPM]":"22.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.3","Single Cell Type RNA - Fibroblasts [nTPM]":"5.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.6","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"13.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"7.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.9","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.7","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"12.2","Single Cell Type RNA - Langerhans cells [nTPM]":"6.0","Single Cell Type RNA - Late spermatids [nTPM]":"6.3","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"7.8","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"7.6","Single Cell Type RNA - Muller glia cells [nTPM]":"3.0","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.0","Single Cell Type RNA - Paneth cells [nTPM]":"2.7","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"11.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.6","Single Cell Type RNA - Spermatocytes [nTPM]":"48.5","Single Cell Type RNA - Spermatogonia [nTPM]":"31.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.5","Single Cell Type RNA - T-cells [nTPM]":"10.6","Single Cell Type RNA - Theca cells [nTPM]":"3.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.5","Single Cell Type RNA - Urothelial cells [nTPM]":"11.4"},{"Gene":"RGR","Gene synonym":["RP44"],"Ensembl":"ENSG00000148604","Gene description":"Retinal G protein coupled receptor","Uniprot":["P47804"],"Chromosome":"10","Position":"84230666-84259960","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["G-protein coupled receptor","Photoreceptor protein","Receptor","Retinal protein","Transducer"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"retina":"139.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"29","RNA single cell type specific nTPM":{"Muller glia cells":"1475.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"0.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"midbrain":"23.4","olfactory bulb":"49.7","thalamus":"27.3"},"Antibody":["HPA059149"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 5: Muller glia cells - Visual perception","Subcellular main location":["Vesicles"],"Subcellular additional location":["Plasma membrane","Cytosol"],"Antibody RRID":{"HPA059149":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"11.9","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"11.9","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"4.4","Tissue RNA - cerebral cortex [nTPM]":"14.6","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"14.4","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"7.4","Tissue RNA - hypothalamus [nTPM]":"8.5","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"5.2","Tissue RNA - midbrain [nTPM]":"8.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.4","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"5.4","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"139.0","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"3.1","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"10.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"6.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"11.9","Brain RNA - basal ganglia [nTPM]":"11.9","Brain RNA - cerebellum [nTPM]":"4.4","Brain RNA - cerebral cortex [nTPM]":"14.6","Brain RNA - hippocampal formation [nTPM]":"7.4","Brain RNA - hypothalamus [nTPM]":"8.5","Brain RNA - medulla oblongata [nTPM]":"5.2","Brain RNA - midbrain [nTPM]":"8.2","Brain RNA - pons [nTPM]":"5.4","Brain RNA - spinal cord [nTPM]":"3.1","Brain RNA - thalamus [nTPM]":"10.1","Brain RNA - white matter [nTPM]":"6.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"20.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"8.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"10.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1475.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"49.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.9","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"RHAG","Gene synonym":["CD241","RH50A","SLC42A1"],"Ensembl":"ENSG00000112077","Gene description":"Rh associated glycoprotein","Uniprot":["Q02094"],"Chromosome":"6","Position":"49605175-49636839","Protein class":["CD markers","Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ammonia transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Hereditary hemolytic anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"54","RNA tissue specific nTPM":{"bone marrow":"119.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"170","RNA single cell type specific nTPM":{"Erythroid cells":"494.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"202","RNA cell line specific nTPM":{"HEL":"506.0","K-562":"491.0"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046051","HPA055331"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA046051":null,"HPA055331":"AB_2682785"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"119.6","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.7","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.5","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"2.1","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"2.2","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"1.7","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"506.0","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"491.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"2.4","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"494.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.6","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.6","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"2.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"RHBDF2","Gene synonym":["FLJ22341","iRhom2","RHBDL5","RHBDL6","TOC","TOCG"],"Ensembl":"ENSG00000129667","Gene description":"Rhomboid 5 homolog 2","Uniprot":["Q6PJF5"],"Chromosome":"17","Position":"76470891-76501790","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":["Growth factor binding"],"Disease involvement":["Disease variant","Palmoplantar keratoderma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"58.4","Kupffer cells":"57.3","NK-cells":"64.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RPMI-8226":"75.3"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018080"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018080":"AB_2178634"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.96e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Tissue RNA - adipose tissue [nTPM]":"18.3","Tissue RNA - adrenal gland [nTPM]":"10.1","Tissue RNA - amygdala [nTPM]":"9.4","Tissue RNA - appendix [nTPM]":"31.2","Tissue RNA - basal ganglia [nTPM]":"8.6","Tissue RNA - bone marrow [nTPM]":"29.7","Tissue RNA - breast [nTPM]":"13.6","Tissue RNA - cerebellum [nTPM]":"11.7","Tissue RNA - cerebral cortex [nTPM]":"11.0","Tissue RNA - cervix [nTPM]":"8.8","Tissue RNA - choroid plexus [nTPM]":"11.6","Tissue RNA - colon [nTPM]":"9.0","Tissue RNA - duodenum [nTPM]":"6.5","Tissue RNA - endometrium 1 [nTPM]":"7.4","Tissue RNA - epididymis [nTPM]":"1.6","Tissue RNA - esophagus [nTPM]":"23.9","Tissue RNA - fallopian tube [nTPM]":"10.1","Tissue RNA - gallbladder [nTPM]":"10.3","Tissue RNA - heart muscle [nTPM]":"10.3","Tissue RNA - hippocampal formation [nTPM]":"9.7","Tissue RNA - hypothalamus [nTPM]":"12.1","Tissue RNA - kidney [nTPM]":"10.9","Tissue RNA - liver [nTPM]":"6.3","Tissue RNA - lung [nTPM]":"24.8","Tissue RNA - lymph node [nTPM]":"27.6","Tissue RNA - medulla oblongata [nTPM]":"26.6","Tissue RNA - midbrain [nTPM]":"17.2","Tissue RNA - ovary [nTPM]":"8.0","Tissue RNA - pancreas [nTPM]":"19.5","Tissue RNA - parathyroid gland [nTPM]":"3.1","Tissue RNA - pituitary gland [nTPM]":"5.3","Tissue RNA - placenta [nTPM]":"9.7","Tissue RNA - pons [nTPM]":"22.4","Tissue RNA - prostate [nTPM]":"9.1","Tissue RNA - rectum [nTPM]":"4.4","Tissue RNA - retina [nTPM]":"2.9","Tissue RNA - salivary gland [nTPM]":"11.6","Tissue RNA - seminal vesicle [nTPM]":"2.6","Tissue RNA - skeletal muscle [nTPM]":"13.5","Tissue RNA - skin 1 [nTPM]":"29.1","Tissue RNA - small intestine [nTPM]":"26.6","Tissue RNA - smooth muscle [nTPM]":"6.4","Tissue RNA - spinal cord [nTPM]":"20.9","Tissue RNA - spleen [nTPM]":"42.2","Tissue RNA - stomach 1 [nTPM]":"10.5","Tissue RNA - testis [nTPM]":"3.0","Tissue RNA - thalamus [nTPM]":"30.0","Tissue RNA - thymus [nTPM]":"6.5","Tissue RNA - thyroid gland [nTPM]":"12.3","Tissue RNA - tongue [nTPM]":"3.1","Tissue RNA - tonsil [nTPM]":"21.3","Tissue RNA - urinary bladder [nTPM]":"11.0","Tissue RNA - vagina [nTPM]":"15.7","Tissue RNA - white matter [nTPM]":"28.8","Cell RNA - A-431 [nTPM]":"38.3","Cell RNA - A549 [nTPM]":"43.3","Cell RNA - AF22 [nTPM]":"1.3","Cell RNA - AN3-CA [nTPM]":"10.7","Cell RNA - ASC diff [nTPM]":"0.4","Cell RNA - ASC TERT1 [nTPM]":"1.1","Cell RNA - BEWO [nTPM]":"30.1","Cell RNA - BJ [nTPM]":"8.6","Cell RNA - BJ hTERT+ [nTPM]":"26.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.1","Cell RNA - CACO-2 [nTPM]":"13.3","Cell RNA - CAPAN-2 [nTPM]":"45.0","Cell RNA - Daudi [nTPM]":"41.5","Cell RNA - EFO-21 [nTPM]":"28.6","Cell RNA - fHDF\/TERT166 [nTPM]":"10.9","Cell RNA - GAMG [nTPM]":"39.0","Cell RNA - HaCaT [nTPM]":"29.9","Cell RNA - HAP1 [nTPM]":"7.3","Cell RNA - HBEC3-KT [nTPM]":"40.8","Cell RNA - HBF TERT88 [nTPM]":"6.2","Cell RNA - HDLM-2 [nTPM]":"7.1","Cell RNA - HEK 293 [nTPM]":"13.6","Cell RNA - HEL [nTPM]":"2.8","Cell RNA - HeLa [nTPM]":"3.5","Cell RNA - Hep G2 [nTPM]":"21.8","Cell RNA - HHSteC [nTPM]":"25.6","Cell RNA - HL-60 [nTPM]":"1.8","Cell RNA - HMC-1 [nTPM]":"5.9","Cell RNA - HSkMC [nTPM]":"4.5","Cell RNA - hTCEpi [nTPM]":"20.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.1","Cell RNA - hTERT-HME1 [nTPM]":"20.7","Cell RNA - hTERT-RPE1 [nTPM]":"15.4","Cell RNA - HUVEC TERT2 [nTPM]":"20.3","Cell RNA - JURKAT [nTPM]":"5.9","Cell RNA - K-562 [nTPM]":"4.3","Cell RNA - Karpas-707 [nTPM]":"18.3","Cell RNA - LHCN-M2 [nTPM]":"4.6","Cell RNA - MCF7 [nTPM]":"30.7","Cell RNA - MOLT-4 [nTPM]":"4.3","Cell RNA - NB-4 [nTPM]":"4.7","Cell RNA - NTERA-2 [nTPM]":"6.7","Cell RNA - OE19 [nTPM]":"25.7","Cell RNA - PC-3 [nTPM]":"26.1","Cell RNA - REH [nTPM]":"10.3","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"75.3","Cell RNA - RPTEC TERT1 [nTPM]":"17.8","Cell RNA - RT4 [nTPM]":"14.0","Cell RNA - SCLC-21H [nTPM]":"9.2","Cell RNA - SH-SY5Y [nTPM]":"12.6","Cell RNA - SiHa [nTPM]":"9.9","Cell RNA - SK-BR-3 [nTPM]":"28.7","Cell RNA - SK-MEL-30 [nTPM]":"38.7","Cell RNA - SuSa [nTPM]":"8.5","Cell RNA - T-47d [nTPM]":"24.7","Cell RNA - THP-1 [nTPM]":"11.4","Cell RNA - TIME [nTPM]":"32.4","Cell RNA - U-138 MG [nTPM]":"0.6","Cell RNA - U-2 OS [nTPM]":"14.4","Cell RNA - U-2197 [nTPM]":"0.7","Cell RNA - U-251 MG [nTPM]":"11.0","Cell RNA - U-266\/70 [nTPM]":"44.3","Cell RNA - U-266\/84 [nTPM]":"22.6","Cell RNA - U-698 [nTPM]":"33.7","Cell RNA - U-87 MG [nTPM]":"24.3","Cell RNA - U-937 [nTPM]":"11.2","Cell RNA - WM-115 [nTPM]":"27.1","Blood RNA - basophil [nTPM]":"6.3","Blood RNA - classical monocyte [nTPM]":"13.4","Blood RNA - eosinophil [nTPM]":"4.3","Blood RNA - gdT-cell [nTPM]":"8.0","Blood RNA - intermediate monocyte [nTPM]":"13.1","Blood RNA - MAIT T-cell [nTPM]":"5.5","Blood RNA - memory B-cell [nTPM]":"12.7","Blood RNA - memory CD4 T-cell [nTPM]":"2.1","Blood RNA - memory CD8 T-cell [nTPM]":"5.8","Blood RNA - myeloid DC [nTPM]":"6.5","Blood RNA - naive B-cell [nTPM]":"7.4","Blood RNA - naive CD4 T-cell [nTPM]":"1.5","Blood RNA - naive CD8 T-cell [nTPM]":"3.6","Blood RNA - neutrophil [nTPM]":"10.2","Blood RNA - NK-cell [nTPM]":"4.9","Blood RNA - non-classical monocyte [nTPM]":"12.2","Blood RNA - plasmacytoid DC [nTPM]":"10.0","Blood RNA - T-reg [nTPM]":"1.1","Blood RNA - total PBMC [nTPM]":"8.8","Brain RNA - amygdala [nTPM]":"9.4","Brain RNA - basal ganglia [nTPM]":"8.6","Brain RNA - cerebellum [nTPM]":"11.7","Brain RNA - cerebral cortex [nTPM]":"11.0","Brain RNA - hippocampal formation [nTPM]":"9.7","Brain RNA - hypothalamus [nTPM]":"12.1","Brain RNA - medulla oblongata [nTPM]":"26.6","Brain RNA - midbrain [nTPM]":"17.2","Brain RNA - pons [nTPM]":"22.4","Brain RNA - spinal cord [nTPM]":"20.9","Brain RNA - thalamus [nTPM]":"30.0","Brain RNA - white matter [nTPM]":"28.8","Single Cell Type RNA - Adipocytes [nTPM]":"22.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.9","Single Cell Type RNA - Astrocytes [nTPM]":"2.3","Single Cell Type RNA - B-cells [nTPM]":"58.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"35.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"4.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"19.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - dendritic cells [nTPM]":"47.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"21.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.8","Single Cell Type RNA - Endothelial cells [nTPM]":"15.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.2","Single Cell Type RNA - Fibroblasts [nTPM]":"4.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"15.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"3.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"37.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.1","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"57.3","Single Cell Type RNA - Langerhans cells [nTPM]":"42.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"48.8","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"38.4","Single Cell Type RNA - monocytes [nTPM]":"40.1","Single Cell Type RNA - Muller glia cells [nTPM]":"1.1","Single Cell Type RNA - NK-cells [nTPM]":"64.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.2","Single Cell Type RNA - Paneth cells [nTPM]":"4.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"36.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"7.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"29.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.6","Single Cell Type RNA - T-cells [nTPM]":"22.3","Single Cell Type RNA - Theca cells [nTPM]":"2.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.8","Single Cell Type RNA - Urothelial cells [nTPM]":"20.4"},{"Gene":"RHCE","Gene synonym":["CD240CE","RH"],"Ensembl":"ENSG00000188672","Gene description":"Rh blood group CcEe antigens","Uniprot":["P18577"],"Chromosome":"1","Position":"25362249-25430192","Protein class":["Blood group antigen proteins","CD markers","Disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Blood group antigen"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"bone marrow":"48.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"67","RNA single cell type specific nTPM":{"Erythroid cells":"511.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"HEL":"81.3"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060951","HPA077385"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA060951":null,"HPA077385":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.6","Tissue RNA - amygdala [nTPM]":"1.5","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"1.9","Tissue RNA - bone marrow [nTPM]":"48.5","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"1.6","Tissue RNA - cerebral cortex [nTPM]":"3.3","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"1.2","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"4.2","Tissue RNA - esophagus [nTPM]":"0.6","Tissue RNA - fallopian tube [nTPM]":"1.0","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"1.2","Tissue RNA - hippocampal formation [nTPM]":"1.5","Tissue RNA - hypothalamus [nTPM]":"1.4","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"1.7","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"1.9","Tissue RNA - midbrain [nTPM]":"1.6","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"1.2","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"3.4","Tissue RNA - placenta [nTPM]":"1.1","Tissue RNA - pons [nTPM]":"1.9","Tissue RNA - prostate [nTPM]":"1.0","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"2.2","Tissue RNA - salivary gland [nTPM]":"5.5","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"1.5","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"1.5","Tissue RNA - spleen [nTPM]":"1.1","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"2.2","Tissue RNA - thalamus [nTPM]":"1.6","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"0.6","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"2.2","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.5","Cell RNA - ASC diff [nTPM]":"0.9","Cell RNA - ASC TERT1 [nTPM]":"0.6","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"1.5","Cell RNA - Daudi [nTPM]":"0.7","Cell RNA - EFO-21 [nTPM]":"1.1","Cell RNA - fHDF\/TERT166 [nTPM]":"1.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"81.3","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"1.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"1.9","Cell RNA - hTCEpi [nTPM]":"1.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.6","Cell RNA - hTERT-HME1 [nTPM]":"0.5","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.6","Cell RNA - K-562 [nTPM]":"17.5","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"0.8","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"1.7","Cell RNA - OE19 [nTPM]":"0.7","Cell RNA - PC-3 [nTPM]":"0.5","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"2.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"0.8","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"1.0","Cell RNA - SuSa [nTPM]":"0.8","Cell RNA - T-47d [nTPM]":"0.5","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.9","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"5.1","Cell RNA - U-266\/84 [nTPM]":"1.4","Cell RNA - U-698 [nTPM]":"1.0","Cell RNA - U-87 MG [nTPM]":"2.9","Cell RNA - U-937 [nTPM]":"0.9","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"1.5","Brain RNA - basal ganglia [nTPM]":"1.9","Brain RNA - cerebellum [nTPM]":"1.6","Brain RNA - cerebral cortex [nTPM]":"3.3","Brain RNA - hippocampal formation [nTPM]":"1.5","Brain RNA - hypothalamus [nTPM]":"1.4","Brain RNA - medulla oblongata [nTPM]":"1.9","Brain RNA - midbrain [nTPM]":"1.6","Brain RNA - pons [nTPM]":"1.9","Brain RNA - spinal cord [nTPM]":"1.5","Brain RNA - thalamus [nTPM]":"1.6","Brain RNA - white matter [nTPM]":"2.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"0.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"4.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - dendritic cells [nTPM]":"1.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"511.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.8","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"1.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.7","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"3.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"3.0","Single Cell Type RNA - Spermatogonia [nTPM]":"7.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"0.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"RHO","Gene synonym":["CSNBAD1","OPN2","RP4"],"Ensembl":"ENSG00000163914","Gene description":"Rhodopsin","Uniprot":["P08100"],"Chromosome":"3","Position":"129528639-129535344","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["G-protein coupled receptor","Photoreceptor protein","Receptor","Retinal protein","Transducer"],"Disease involvement":["Congenital stationary night blindness","Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"5994","RNA tissue specific nTPM":{"retina":"4062.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Rod photoreceptor cells":"4509.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"hippocampal formation":"9.7"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"hippocampal formation":"1.1"},"Antibody":["HPA013440","CAB022486","CAB034887","CAB034888"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022486":null,"CAB034887":"AB_785511","CAB034888":"AB_785512","HPA013440":"AB_2668844"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"4062.1","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"369.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"454.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"26.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"218.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"590.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4509.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"RHOA","Gene synonym":["ARH12","ARHA","Rho12","RHOH12"],"Ensembl":"ENSG00000067560","Gene description":"Ras homolog family member A","Uniprot":["P61586"],"Chromosome":"3","Position":"49359139-49412998","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["Cell cycle","Cell division","Host-virus interaction"],"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Ectodermal dysplasia","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005052"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1500000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB005052":"AB_562216"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.08e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.15e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.21e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"},"Tissue RNA - adipose tissue [nTPM]":"452.4","Tissue RNA - adrenal gland [nTPM]":"315.0","Tissue RNA - amygdala [nTPM]":"234.6","Tissue RNA - appendix [nTPM]":"357.9","Tissue RNA - basal ganglia [nTPM]":"258.6","Tissue RNA - bone marrow [nTPM]":"473.4","Tissue RNA - breast [nTPM]":"360.0","Tissue RNA - cerebellum [nTPM]":"257.1","Tissue RNA - cerebral cortex [nTPM]":"274.1","Tissue RNA - cervix [nTPM]":"310.4","Tissue RNA - choroid plexus [nTPM]":"237.4","Tissue RNA - colon [nTPM]":"351.9","Tissue RNA - duodenum [nTPM]":"274.6","Tissue RNA - endometrium 1 [nTPM]":"293.8","Tissue RNA - epididymis [nTPM]":"298.6","Tissue RNA - esophagus [nTPM]":"362.6","Tissue RNA - fallopian tube [nTPM]":"269.2","Tissue RNA - gallbladder [nTPM]":"267.1","Tissue RNA - heart muscle [nTPM]":"269.6","Tissue RNA - hippocampal formation [nTPM]":"220.8","Tissue RNA - hypothalamus [nTPM]":"271.2","Tissue RNA - kidney [nTPM]":"286.9","Tissue RNA - liver [nTPM]":"274.5","Tissue RNA - lung [nTPM]":"430.9","Tissue RNA - lymph node [nTPM]":"396.3","Tissue RNA - medulla oblongata [nTPM]":"282.9","Tissue RNA - midbrain [nTPM]":"245.8","Tissue RNA - ovary [nTPM]":"297.2","Tissue RNA - pancreas [nTPM]":"225.3","Tissue RNA - parathyroid gland [nTPM]":"269.4","Tissue RNA - pituitary gland [nTPM]":"164.3","Tissue RNA - placenta [nTPM]":"396.8","Tissue RNA - pons [nTPM]":"287.2","Tissue RNA - prostate [nTPM]":"244.5","Tissue RNA - rectum [nTPM]":"369.3","Tissue RNA - retina [nTPM]":"113.3","Tissue RNA - salivary gland [nTPM]":"238.0","Tissue RNA - seminal vesicle [nTPM]":"315.6","Tissue RNA - skeletal muscle [nTPM]":"331.0","Tissue RNA - skin 1 [nTPM]":"281.3","Tissue RNA - small intestine [nTPM]":"281.0","Tissue RNA - smooth muscle [nTPM]":"416.9","Tissue RNA - spinal cord [nTPM]":"259.3","Tissue RNA - spleen [nTPM]":"329.1","Tissue RNA - stomach 1 [nTPM]":"292.1","Tissue RNA - testis [nTPM]":"154.1","Tissue RNA - thalamus [nTPM]":"257.5","Tissue RNA - thymus [nTPM]":"387.7","Tissue RNA - thyroid gland [nTPM]":"326.3","Tissue RNA - tongue [nTPM]":"298.5","Tissue RNA - tonsil [nTPM]":"454.9","Tissue RNA - urinary bladder [nTPM]":"358.2","Tissue RNA - vagina [nTPM]":"273.6","Tissue RNA - white matter [nTPM]":"292.5","Cell RNA - A-431 [nTPM]":"470.4","Cell RNA - A549 [nTPM]":"406.1","Cell RNA - AF22 [nTPM]":"500.9","Cell RNA - AN3-CA [nTPM]":"512.7","Cell RNA - ASC diff [nTPM]":"569.9","Cell RNA - ASC TERT1 [nTPM]":"858.9","Cell RNA - BEWO [nTPM]":"370.8","Cell RNA - BJ [nTPM]":"930.1","Cell RNA - BJ hTERT+ [nTPM]":"735.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"790.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"722.4","Cell RNA - CACO-2 [nTPM]":"347.6","Cell RNA - CAPAN-2 [nTPM]":"527.4","Cell RNA - Daudi [nTPM]":"721.8","Cell RNA - EFO-21 [nTPM]":"251.6","Cell RNA - fHDF\/TERT166 [nTPM]":"1404.1","Cell RNA - GAMG [nTPM]":"448.8","Cell RNA - HaCaT [nTPM]":"259.5","Cell RNA - HAP1 [nTPM]":"560.4","Cell RNA - HBEC3-KT [nTPM]":"630.6","Cell RNA - HBF TERT88 [nTPM]":"817.6","Cell RNA - HDLM-2 [nTPM]":"505.7","Cell RNA - HEK 293 [nTPM]":"323.3","Cell RNA - HEL [nTPM]":"678.8","Cell RNA - HeLa [nTPM]":"488.0","Cell RNA - Hep G2 [nTPM]":"416.0","Cell RNA - HHSteC [nTPM]":"604.2","Cell RNA - HL-60 [nTPM]":"647.9","Cell RNA - HMC-1 [nTPM]":"472.8","Cell RNA - HSkMC [nTPM]":"668.2","Cell RNA - hTCEpi [nTPM]":"437.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"643.2","Cell RNA - hTERT-HME1 [nTPM]":"508.1","Cell RNA - hTERT-RPE1 [nTPM]":"799.7","Cell RNA - HUVEC TERT2 [nTPM]":"1038.0","Cell RNA - JURKAT [nTPM]":"391.9","Cell RNA - K-562 [nTPM]":"361.1","Cell RNA - Karpas-707 [nTPM]":"437.9","Cell RNA - LHCN-M2 [nTPM]":"967.5","Cell RNA - MCF7 [nTPM]":"254.3","Cell RNA - MOLT-4 [nTPM]":"717.3","Cell RNA - NB-4 [nTPM]":"739.0","Cell RNA - NTERA-2 [nTPM]":"441.4","Cell RNA - OE19 [nTPM]":"548.2","Cell RNA - PC-3 [nTPM]":"497.1","Cell RNA - REH [nTPM]":"325.5","Cell RNA - RH-30 [nTPM]":"451.4","Cell RNA - RPMI-8226 [nTPM]":"610.5","Cell RNA - RPTEC TERT1 [nTPM]":"701.9","Cell RNA - RT4 [nTPM]":"559.6","Cell RNA - SCLC-21H [nTPM]":"167.7","Cell RNA - SH-SY5Y [nTPM]":"387.3","Cell RNA - SiHa [nTPM]":"599.0","Cell RNA - SK-BR-3 [nTPM]":"464.5","Cell RNA - SK-MEL-30 [nTPM]":"495.4","Cell RNA - SuSa [nTPM]":"499.4","Cell RNA - T-47d [nTPM]":"301.7","Cell RNA - THP-1 [nTPM]":"819.6","Cell RNA - TIME [nTPM]":"972.1","Cell RNA - U-138 MG [nTPM]":"558.4","Cell RNA - U-2 OS [nTPM]":"483.2","Cell RNA - U-2197 [nTPM]":"737.2","Cell RNA - U-251 MG [nTPM]":"725.7","Cell RNA - U-266\/70 [nTPM]":"388.0","Cell RNA - U-266\/84 [nTPM]":"775.6","Cell RNA - U-698 [nTPM]":"754.8","Cell RNA - U-87 MG [nTPM]":"567.9","Cell RNA - U-937 [nTPM]":"691.6","Cell RNA - WM-115 [nTPM]":"678.3","Blood RNA - basophil [nTPM]":"716.9","Blood RNA - classical monocyte [nTPM]":"1105.5","Blood RNA - eosinophil [nTPM]":"1160.5","Blood RNA - gdT-cell [nTPM]":"480.1","Blood RNA - intermediate monocyte [nTPM]":"1358.8","Blood RNA - MAIT T-cell [nTPM]":"423.8","Blood RNA - memory B-cell [nTPM]":"432.7","Blood RNA - memory CD4 T-cell [nTPM]":"415.6","Blood RNA - memory CD8 T-cell [nTPM]":"479.6","Blood RNA - myeloid DC [nTPM]":"806.9","Blood RNA - naive B-cell [nTPM]":"379.3","Blood RNA - naive CD4 T-cell [nTPM]":"314.5","Blood RNA - naive CD8 T-cell [nTPM]":"397.1","Blood RNA - neutrophil [nTPM]":"1282.7","Blood RNA - NK-cell [nTPM]":"440.9","Blood RNA - non-classical monocyte [nTPM]":"1398.1","Blood RNA - plasmacytoid DC [nTPM]":"645.5","Blood RNA - T-reg [nTPM]":"554.9","Blood RNA - total PBMC [nTPM]":"1884.8","Brain RNA - amygdala [nTPM]":"234.6","Brain RNA - basal ganglia [nTPM]":"258.6","Brain RNA - cerebellum [nTPM]":"257.1","Brain RNA - cerebral cortex [nTPM]":"274.1","Brain RNA - hippocampal formation [nTPM]":"220.8","Brain RNA - hypothalamus [nTPM]":"271.2","Brain RNA - medulla oblongata [nTPM]":"282.9","Brain RNA - midbrain [nTPM]":"245.8","Brain RNA - pons [nTPM]":"287.2","Brain RNA - spinal cord [nTPM]":"259.3","Brain RNA - thalamus [nTPM]":"257.5","Brain RNA - white matter [nTPM]":"292.5","Single Cell Type RNA - Adipocytes [nTPM]":"502.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"387.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"265.2","Single Cell Type RNA - Astrocytes [nTPM]":"20.5","Single Cell Type RNA - B-cells [nTPM]":"374.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"270.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"260.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"236.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"251.6","Single Cell Type RNA - Bipolar cells [nTPM]":"47.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"239.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"223.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"141.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"178.7","Single Cell Type RNA - Club cells [nTPM]":"220.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"180.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"355.8","Single Cell Type RNA - dendritic cells [nTPM]":"373.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"447.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"340.4","Single Cell Type RNA - Ductal cells [nTPM]":"339.5","Single Cell Type RNA - Early spermatids [nTPM]":"48.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"174.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"243.7","Single Cell Type RNA - Endothelial cells [nTPM]":"413.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"234.4","Single Cell Type RNA - Erythroid cells [nTPM]":"319.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"26.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"347.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"709.8","Single Cell Type RNA - Fibroblasts [nTPM]":"386.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"313.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"201.0","Single Cell Type RNA - granulocytes [nTPM]":"257.3","Single Cell Type RNA - Granulosa cells [nTPM]":"141.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"312.7","Single Cell Type RNA - Hepatocytes [nTPM]":"173.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"760.0","Single Cell Type RNA - Horizontal cells [nTPM]":"82.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"27.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"344.9","Single Cell Type RNA - Ionocytes [nTPM]":"191.2","Single Cell Type RNA - Kupffer cells [nTPM]":"771.9","Single Cell Type RNA - Langerhans cells [nTPM]":"495.8","Single Cell Type RNA - Late spermatids [nTPM]":"55.6","Single Cell Type RNA - Leydig cells [nTPM]":"335.2","Single Cell Type RNA - Macrophages [nTPM]":"683.7","Single Cell Type RNA - Melanocytes [nTPM]":"327.3","Single Cell Type RNA - Microglial cells [nTPM]":"52.5","Single Cell Type RNA - monocytes [nTPM]":"710.0","Single Cell Type RNA - Muller glia cells [nTPM]":"219.9","Single Cell Type RNA - NK-cells [nTPM]":"389.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"24.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"51.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"398.0","Single Cell Type RNA - Paneth cells [nTPM]":"354.6","Single Cell Type RNA - Peritubular cells [nTPM]":"407.7","Single Cell Type RNA - Plasma cells [nTPM]":"375.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"334.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"341.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"350.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"201.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"40.8","Single Cell Type RNA - Sertoli cells [nTPM]":"276.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"354.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"450.1","Single Cell Type RNA - Spermatocytes [nTPM]":"264.4","Single Cell Type RNA - Spermatogonia [nTPM]":"253.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"390.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"279.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"525.2","Single Cell Type RNA - T-cells [nTPM]":"359.5","Single Cell Type RNA - Theca cells [nTPM]":"299.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"347.7","Single Cell Type RNA - Urothelial cells [nTPM]":"371.4"},{"Gene":"RIPK1","Gene synonym":["RIP"],"Ensembl":"ENSG00000137275","Gene description":"Receptor interacting serine\/threonine kinase 1","Uniprot":["Q13546"],"Chromosome":"6","Position":"3063824-3115187","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Host-virus interaction","Inflammatory response","Necrosis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010302","HPA015257"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB010302":"AB_2178118","HPA015257":"AB_1856294"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.71e-4"},"Tissue RNA - adipose tissue [nTPM]":"18.5","Tissue RNA - adrenal gland [nTPM]":"12.0","Tissue RNA - amygdala [nTPM]":"1.9","Tissue RNA - appendix [nTPM]":"9.3","Tissue RNA - basal ganglia [nTPM]":"1.9","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"16.2","Tissue RNA - cerebellum [nTPM]":"1.8","Tissue RNA - cerebral cortex [nTPM]":"3.8","Tissue RNA - cervix [nTPM]":"12.8","Tissue RNA - choroid plexus [nTPM]":"2.4","Tissue RNA - colon [nTPM]":"17.5","Tissue RNA - duodenum [nTPM]":"12.3","Tissue RNA - endometrium 1 [nTPM]":"14.5","Tissue RNA - epididymis [nTPM]":"5.3","Tissue RNA - esophagus [nTPM]":"17.6","Tissue RNA - fallopian tube [nTPM]":"12.8","Tissue RNA - gallbladder [nTPM]":"10.6","Tissue RNA - heart muscle [nTPM]":"11.8","Tissue RNA - hippocampal formation [nTPM]":"1.8","Tissue RNA - hypothalamus [nTPM]":"1.9","Tissue RNA - kidney [nTPM]":"13.7","Tissue RNA - liver [nTPM]":"23.6","Tissue RNA - lung [nTPM]":"13.5","Tissue RNA - lymph node [nTPM]":"10.1","Tissue RNA - medulla oblongata [nTPM]":"2.2","Tissue RNA - midbrain [nTPM]":"1.9","Tissue RNA - ovary [nTPM]":"8.5","Tissue RNA - pancreas [nTPM]":"17.4","Tissue RNA - parathyroid gland [nTPM]":"12.2","Tissue RNA - pituitary gland [nTPM]":"12.3","Tissue RNA - placenta [nTPM]":"10.9","Tissue RNA - pons [nTPM]":"2.0","Tissue RNA - prostate [nTPM]":"13.7","Tissue RNA - rectum [nTPM]":"13.0","Tissue RNA - retina [nTPM]":"2.4","Tissue RNA - salivary gland [nTPM]":"16.4","Tissue RNA - seminal vesicle [nTPM]":"8.9","Tissue RNA - skeletal muscle [nTPM]":"11.7","Tissue RNA - skin 1 [nTPM]":"20.7","Tissue RNA - small intestine [nTPM]":"19.9","Tissue RNA - smooth muscle [nTPM]":"11.9","Tissue RNA - spinal cord [nTPM]":"2.0","Tissue RNA - spleen [nTPM]":"19.4","Tissue RNA - stomach 1 [nTPM]":"16.5","Tissue RNA - testis [nTPM]":"5.3","Tissue RNA - thalamus [nTPM]":"2.0","Tissue RNA - thymus [nTPM]":"11.9","Tissue RNA - thyroid gland [nTPM]":"14.4","Tissue RNA - tongue [nTPM]":"5.0","Tissue RNA - tonsil [nTPM]":"13.0","Tissue RNA - urinary bladder [nTPM]":"15.5","Tissue RNA - vagina [nTPM]":"13.7","Tissue RNA - white matter [nTPM]":"1.9","Cell RNA - A-431 [nTPM]":"14.4","Cell RNA - A549 [nTPM]":"9.8","Cell RNA - AF22 [nTPM]":"12.9","Cell RNA - AN3-CA [nTPM]":"12.4","Cell RNA - ASC diff [nTPM]":"27.6","Cell RNA - ASC TERT1 [nTPM]":"19.2","Cell RNA - BEWO [nTPM]":"5.5","Cell RNA - BJ [nTPM]":"21.4","Cell RNA - BJ hTERT+ [nTPM]":"30.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"22.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"26.7","Cell RNA - CACO-2 [nTPM]":"12.4","Cell RNA - CAPAN-2 [nTPM]":"8.0","Cell RNA - Daudi [nTPM]":"13.8","Cell RNA - EFO-21 [nTPM]":"20.9","Cell RNA - fHDF\/TERT166 [nTPM]":"30.1","Cell RNA - GAMG [nTPM]":"23.2","Cell RNA - HaCaT [nTPM]":"14.3","Cell RNA - HAP1 [nTPM]":"17.9","Cell RNA - HBEC3-KT [nTPM]":"17.2","Cell RNA - HBF TERT88 [nTPM]":"24.3","Cell RNA - HDLM-2 [nTPM]":"27.8","Cell RNA - HEK 293 [nTPM]":"9.4","Cell RNA - HEL [nTPM]":"16.7","Cell RNA - HeLa [nTPM]":"4.5","Cell RNA - Hep G2 [nTPM]":"6.9","Cell RNA - HHSteC [nTPM]":"17.2","Cell RNA - HL-60 [nTPM]":"15.6","Cell RNA - HMC-1 [nTPM]":"20.1","Cell RNA - HSkMC [nTPM]":"24.8","Cell RNA - hTCEpi [nTPM]":"15.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.4","Cell RNA - hTERT-HME1 [nTPM]":"15.3","Cell RNA - hTERT-RPE1 [nTPM]":"17.6","Cell RNA - HUVEC TERT2 [nTPM]":"20.6","Cell RNA - JURKAT [nTPM]":"6.2","Cell RNA - K-562 [nTPM]":"19.4","Cell RNA - Karpas-707 [nTPM]":"4.6","Cell RNA - LHCN-M2 [nTPM]":"22.0","Cell RNA - MCF7 [nTPM]":"17.8","Cell RNA - MOLT-4 [nTPM]":"10.7","Cell RNA - NB-4 [nTPM]":"7.7","Cell RNA - NTERA-2 [nTPM]":"8.8","Cell RNA - OE19 [nTPM]":"17.4","Cell RNA - PC-3 [nTPM]":"12.7","Cell RNA - REH [nTPM]":"11.8","Cell RNA - RH-30 [nTPM]":"10.9","Cell RNA - RPMI-8226 [nTPM]":"14.5","Cell RNA - RPTEC TERT1 [nTPM]":"17.3","Cell RNA - RT4 [nTPM]":"27.2","Cell RNA - SCLC-21H [nTPM]":"11.3","Cell RNA - SH-SY5Y [nTPM]":"12.2","Cell RNA - SiHa [nTPM]":"14.7","Cell RNA - SK-BR-3 [nTPM]":"7.8","Cell RNA - SK-MEL-30 [nTPM]":"22.4","Cell RNA - SuSa [nTPM]":"26.0","Cell RNA - T-47d [nTPM]":"15.2","Cell RNA - THP-1 [nTPM]":"8.7","Cell RNA - TIME [nTPM]":"25.1","Cell RNA - U-138 MG [nTPM]":"20.6","Cell RNA - U-2 OS [nTPM]":"12.1","Cell RNA - U-2197 [nTPM]":"8.2","Cell RNA - U-251 MG [nTPM]":"16.4","Cell RNA - U-266\/70 [nTPM]":"9.8","Cell RNA - U-266\/84 [nTPM]":"15.3","Cell RNA - U-698 [nTPM]":"13.5","Cell RNA - U-87 MG [nTPM]":"8.9","Cell RNA - U-937 [nTPM]":"7.0","Cell RNA - WM-115 [nTPM]":"27.7","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.9","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"1.0","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"1.7","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"1.9","Brain RNA - basal ganglia [nTPM]":"1.9","Brain RNA - cerebellum [nTPM]":"1.8","Brain RNA - cerebral cortex [nTPM]":"3.8","Brain RNA - hippocampal formation [nTPM]":"1.8","Brain RNA - hypothalamus [nTPM]":"1.9","Brain RNA - medulla oblongata [nTPM]":"2.2","Brain RNA - midbrain [nTPM]":"1.9","Brain RNA - pons [nTPM]":"2.0","Brain RNA - spinal cord [nTPM]":"2.0","Brain RNA - thalamus [nTPM]":"2.0","Brain RNA - white matter [nTPM]":"1.9","Single Cell Type RNA - Adipocytes [nTPM]":"28.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.0","Single Cell Type RNA - Astrocytes [nTPM]":"17.3","Single Cell Type RNA - B-cells [nTPM]":"14.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"16.5","Single Cell Type RNA - Bipolar cells [nTPM]":"4.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"16.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.9","Single Cell Type RNA - dendritic cells [nTPM]":"21.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"27.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.4","Single Cell Type RNA - Early spermatids [nTPM]":"2.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.0","Single Cell Type RNA - Endothelial cells [nTPM]":"16.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.6","Single Cell Type RNA - Erythroid cells [nTPM]":"7.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.7","Single Cell Type RNA - Fibroblasts [nTPM]":"18.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"27.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.4","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"8.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.0","Single Cell Type RNA - Hepatocytes [nTPM]":"14.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.6","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"26.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.7","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"6.7","Single Cell Type RNA - Langerhans cells [nTPM]":"11.1","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"6.8","Single Cell Type RNA - Macrophages [nTPM]":"15.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"13.8","Single Cell Type RNA - Muller glia cells [nTPM]":"6.6","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.8","Single Cell Type RNA - Paneth cells [nTPM]":"11.7","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"22.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.4","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"32.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.9","Single Cell Type RNA - Spermatocytes [nTPM]":"1.2","Single Cell Type RNA - Spermatogonia [nTPM]":"2.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.9","Single Cell Type RNA - T-cells [nTPM]":"20.8","Single Cell Type RNA - Theca cells [nTPM]":"10.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.3","Single Cell Type RNA - Urothelial cells [nTPM]":"14.5"},{"Gene":"RIPK4","Gene synonym":["ANKK2","ANKRD3","DIK","PKK","RIP4"],"Ensembl":"ENSG00000183421","Gene description":"Receptor interacting serine\/threonine kinase 4","Uniprot":["P57078"],"Chromosome":"21","Position":"41739369-41767089","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Ectodermal dysplasia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"72.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"52.3","Endometrial ciliated cells":"76.5","Gastric mucus-secreting cells":"61.2","Glandular and luminal cells":"174.2","Squamous epithelial cells":"71.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"32.2","GAMG":"41.2","HaCaT":"47.5","hTCEpi":"31.4","RPTEC TERT1":"28.3","RT4":"30.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030942"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA030942":"AB_2732462"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.22e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.48e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.52e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.6","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"4.3","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"11.8","Tissue RNA - choroid plexus [nTPM]":"3.7","Tissue RNA - colon [nTPM]":"3.1","Tissue RNA - duodenum [nTPM]":"9.7","Tissue RNA - endometrium 1 [nTPM]":"1.1","Tissue RNA - epididymis [nTPM]":"2.4","Tissue RNA - esophagus [nTPM]":"72.2","Tissue RNA - fallopian tube [nTPM]":"5.8","Tissue RNA - gallbladder [nTPM]":"5.2","Tissue RNA - heart muscle [nTPM]":"1.5","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"11.5","Tissue RNA - liver [nTPM]":"19.1","Tissue RNA - lung [nTPM]":"4.2","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.6","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"14.3","Tissue RNA - parathyroid gland [nTPM]":"7.4","Tissue RNA - pituitary gland [nTPM]":"10.8","Tissue RNA - placenta [nTPM]":"2.3","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"10.7","Tissue RNA - rectum [nTPM]":"2.0","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"14.8","Tissue RNA - seminal vesicle [nTPM]":"9.8","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"21.5","Tissue RNA - small intestine [nTPM]":"13.6","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"15.5","Tissue RNA - testis [nTPM]":"2.0","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"7.8","Tissue RNA - thyroid gland [nTPM]":"7.9","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"5.2","Tissue RNA - urinary bladder [nTPM]":"6.3","Tissue RNA - vagina [nTPM]":"22.3","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"14.3","Cell RNA - A549 [nTPM]":"9.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"13.7","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"23.5","Cell RNA - CAPAN-2 [nTPM]":"32.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"13.3","Cell RNA - fHDF\/TERT166 [nTPM]":"2.9","Cell RNA - GAMG [nTPM]":"41.2","Cell RNA - HaCaT [nTPM]":"47.5","Cell RNA - HAP1 [nTPM]":"0.7","Cell RNA - HBEC3-KT [nTPM]":"19.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"9.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"6.9","Cell RNA - Hep G2 [nTPM]":"8.8","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"31.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"4.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"14.3","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"10.3","Cell RNA - MOLT-4 [nTPM]":"2.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"9.3","Cell RNA - PC-3 [nTPM]":"26.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"2.3","Cell RNA - RPTEC TERT1 [nTPM]":"28.3","Cell RNA - RT4 [nTPM]":"30.8","Cell RNA - SCLC-21H [nTPM]":"4.5","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"15.5","Cell RNA - SK-BR-3 [nTPM]":"15.7","Cell RNA - SK-MEL-30 [nTPM]":"15.1","Cell RNA - SuSa [nTPM]":"1.3","Cell RNA - T-47d [nTPM]":"9.6","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"4.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"11.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.6","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"24.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"52.3","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"28.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"22.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"12.4","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"76.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.9","Single Cell Type RNA - Endothelial cells [nTPM]":"0.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.7","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"61.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"174.2","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"17.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.2","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"1.4","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.9","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.0","Single Cell Type RNA - Paneth cells [nTPM]":"11.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"24.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"26.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.4","Single Cell Type RNA - Spermatogonia [nTPM]":"2.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"71.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - T-cells [nTPM]":"1.5","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.2","Single Cell Type RNA - Urothelial cells [nTPM]":"24.1"},{"Gene":"RIT1","Gene synonym":["MGC125864","MGC125865","RIBB","RIT","ROC1"],"Ensembl":"ENSG00000143622","Gene description":"Ras like without CAAX 1","Uniprot":["Q92963"],"Chromosome":"1","Position":"155897808-155911404","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"80.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"107.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053249"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053249":"AB_2682089"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.64e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-3"},"Tissue RNA - adipose tissue [nTPM]":"19.8","Tissue RNA - adrenal gland [nTPM]":"13.8","Tissue RNA - amygdala [nTPM]":"10.7","Tissue RNA - appendix [nTPM]":"22.9","Tissue RNA - basal ganglia [nTPM]":"12.1","Tissue RNA - bone marrow [nTPM]":"80.7","Tissue RNA - breast [nTPM]":"13.3","Tissue RNA - cerebellum [nTPM]":"12.0","Tissue RNA - cerebral cortex [nTPM]":"13.0","Tissue RNA - cervix [nTPM]":"16.6","Tissue RNA - choroid plexus [nTPM]":"12.1","Tissue RNA - colon [nTPM]":"14.0","Tissue RNA - duodenum [nTPM]":"12.7","Tissue RNA - endometrium 1 [nTPM]":"14.8","Tissue RNA - epididymis [nTPM]":"15.4","Tissue RNA - esophagus [nTPM]":"37.3","Tissue RNA - fallopian tube [nTPM]":"10.8","Tissue RNA - gallbladder [nTPM]":"18.5","Tissue RNA - heart muscle [nTPM]":"15.7","Tissue RNA - hippocampal formation [nTPM]":"10.3","Tissue RNA - hypothalamus [nTPM]":"11.8","Tissue RNA - kidney [nTPM]":"25.1","Tissue RNA - liver [nTPM]":"12.2","Tissue RNA - lung [nTPM]":"22.7","Tissue RNA - lymph node [nTPM]":"18.3","Tissue RNA - medulla oblongata [nTPM]":"13.5","Tissue RNA - midbrain [nTPM]":"12.7","Tissue RNA - ovary [nTPM]":"12.8","Tissue RNA - pancreas [nTPM]":"13.8","Tissue RNA - parathyroid gland [nTPM]":"16.5","Tissue RNA - pituitary gland [nTPM]":"11.0","Tissue RNA - placenta [nTPM]":"23.0","Tissue RNA - pons [nTPM]":"13.3","Tissue RNA - prostate [nTPM]":"13.8","Tissue RNA - rectum [nTPM]":"14.3","Tissue RNA - retina [nTPM]":"16.0","Tissue RNA - salivary gland [nTPM]":"14.4","Tissue RNA - seminal vesicle [nTPM]":"18.0","Tissue RNA - skeletal muscle [nTPM]":"10.8","Tissue RNA - skin 1 [nTPM]":"12.8","Tissue RNA - small intestine [nTPM]":"12.5","Tissue RNA - smooth muscle [nTPM]":"21.3","Tissue RNA - spinal cord [nTPM]":"11.6","Tissue RNA - spleen [nTPM]":"21.7","Tissue RNA - stomach 1 [nTPM]":"19.7","Tissue RNA - testis [nTPM]":"12.2","Tissue RNA - thalamus [nTPM]":"12.8","Tissue RNA - thymus [nTPM]":"21.5","Tissue RNA - thyroid gland [nTPM]":"13.4","Tissue RNA - tongue [nTPM]":"16.5","Tissue RNA - tonsil [nTPM]":"23.6","Tissue RNA - urinary bladder [nTPM]":"23.6","Tissue RNA - vagina [nTPM]":"21.9","Tissue RNA - white matter [nTPM]":"13.3","Cell RNA - A-431 [nTPM]":"21.0","Cell RNA - A549 [nTPM]":"22.9","Cell RNA - AF22 [nTPM]":"42.3","Cell RNA - AN3-CA [nTPM]":"21.7","Cell RNA - ASC diff [nTPM]":"21.5","Cell RNA - ASC TERT1 [nTPM]":"26.6","Cell RNA - BEWO [nTPM]":"12.0","Cell RNA - BJ [nTPM]":"37.2","Cell RNA - BJ hTERT+ [nTPM]":"37.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"35.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"35.4","Cell RNA - CACO-2 [nTPM]":"24.1","Cell RNA - CAPAN-2 [nTPM]":"40.0","Cell RNA - Daudi [nTPM]":"9.6","Cell RNA - EFO-21 [nTPM]":"50.0","Cell RNA - fHDF\/TERT166 [nTPM]":"43.9","Cell RNA - GAMG [nTPM]":"25.3","Cell RNA - HaCaT [nTPM]":"24.7","Cell RNA - HAP1 [nTPM]":"32.0","Cell RNA - HBEC3-KT [nTPM]":"18.5","Cell RNA - HBF TERT88 [nTPM]":"29.4","Cell RNA - HDLM-2 [nTPM]":"12.9","Cell RNA - HEK 293 [nTPM]":"16.4","Cell RNA - HEL [nTPM]":"21.0","Cell RNA - HeLa [nTPM]":"24.4","Cell RNA - Hep G2 [nTPM]":"15.6","Cell RNA - HHSteC [nTPM]":"55.7","Cell RNA - HL-60 [nTPM]":"22.5","Cell RNA - HMC-1 [nTPM]":"37.9","Cell RNA - HSkMC [nTPM]":"37.1","Cell RNA - hTCEpi [nTPM]":"22.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"40.9","Cell RNA - hTERT-HME1 [nTPM]":"27.4","Cell RNA - hTERT-RPE1 [nTPM]":"47.7","Cell RNA - HUVEC TERT2 [nTPM]":"48.7","Cell RNA - JURKAT [nTPM]":"19.7","Cell RNA - K-562 [nTPM]":"21.0","Cell RNA - Karpas-707 [nTPM]":"26.3","Cell RNA - LHCN-M2 [nTPM]":"54.3","Cell RNA - MCF7 [nTPM]":"27.3","Cell RNA - MOLT-4 [nTPM]":"30.7","Cell RNA - NB-4 [nTPM]":"14.9","Cell RNA - NTERA-2 [nTPM]":"23.0","Cell RNA - OE19 [nTPM]":"36.2","Cell RNA - PC-3 [nTPM]":"13.9","Cell RNA - REH [nTPM]":"24.0","Cell RNA - RH-30 [nTPM]":"33.3","Cell RNA - RPMI-8226 [nTPM]":"19.6","Cell RNA - RPTEC TERT1 [nTPM]":"29.9","Cell RNA - RT4 [nTPM]":"44.2","Cell RNA - SCLC-21H [nTPM]":"19.7","Cell RNA - SH-SY5Y [nTPM]":"30.7","Cell RNA - SiHa [nTPM]":"27.1","Cell RNA - SK-BR-3 [nTPM]":"51.1","Cell RNA - SK-MEL-30 [nTPM]":"34.8","Cell RNA - SuSa [nTPM]":"76.9","Cell RNA - T-47d [nTPM]":"37.3","Cell RNA - THP-1 [nTPM]":"29.4","Cell RNA - TIME [nTPM]":"62.5","Cell RNA - U-138 MG [nTPM]":"31.7","Cell RNA - U-2 OS [nTPM]":"22.3","Cell RNA - U-2197 [nTPM]":"27.3","Cell RNA - U-251 MG [nTPM]":"30.7","Cell RNA - U-266\/70 [nTPM]":"31.1","Cell RNA - U-266\/84 [nTPM]":"30.9","Cell RNA - U-698 [nTPM]":"38.8","Cell RNA - U-87 MG [nTPM]":"33.9","Cell RNA - U-937 [nTPM]":"22.8","Cell RNA - WM-115 [nTPM]":"43.0","Blood RNA - basophil [nTPM]":"22.8","Blood RNA - classical monocyte [nTPM]":"41.0","Blood RNA - eosinophil [nTPM]":"46.9","Blood RNA - gdT-cell [nTPM]":"19.5","Blood RNA - intermediate monocyte [nTPM]":"25.5","Blood RNA - MAIT T-cell [nTPM]":"15.6","Blood RNA - memory B-cell [nTPM]":"16.9","Blood RNA - memory CD4 T-cell [nTPM]":"16.8","Blood RNA - memory CD8 T-cell [nTPM]":"18.5","Blood RNA - myeloid DC [nTPM]":"31.1","Blood RNA - naive B-cell [nTPM]":"17.1","Blood RNA - naive CD4 T-cell [nTPM]":"20.2","Blood RNA - naive CD8 T-cell [nTPM]":"18.1","Blood RNA - neutrophil [nTPM]":"106.3","Blood RNA - NK-cell [nTPM]":"28.8","Blood RNA - non-classical monocyte [nTPM]":"29.3","Blood RNA - plasmacytoid DC [nTPM]":"12.5","Blood RNA - T-reg [nTPM]":"23.8","Blood RNA - total PBMC [nTPM]":"30.0","Brain RNA - amygdala [nTPM]":"10.7","Brain RNA - basal ganglia [nTPM]":"12.1","Brain RNA - cerebellum [nTPM]":"12.0","Brain RNA - cerebral cortex [nTPM]":"13.0","Brain RNA - hippocampal formation [nTPM]":"10.3","Brain RNA - hypothalamus [nTPM]":"11.8","Brain RNA - medulla oblongata [nTPM]":"13.5","Brain RNA - midbrain [nTPM]":"12.7","Brain RNA - pons [nTPM]":"13.3","Brain RNA - spinal cord [nTPM]":"11.6","Brain RNA - thalamus [nTPM]":"12.8","Brain RNA - white matter [nTPM]":"13.3","Single Cell Type RNA - Adipocytes [nTPM]":"45.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.9","Single Cell Type RNA - Astrocytes [nTPM]":"12.4","Single Cell Type RNA - B-cells [nTPM]":"22.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"28.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"36.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"43.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.6","Single Cell Type RNA - Bipolar cells [nTPM]":"8.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"40.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.5","Single Cell Type RNA - dendritic cells [nTPM]":"41.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"39.4","Single Cell Type RNA - Early spermatids [nTPM]":"10.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"25.7","Single Cell Type RNA - Endothelial cells [nTPM]":"50.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.6","Single Cell Type RNA - Erythroid cells [nTPM]":"16.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"16.8","Single Cell Type RNA - Fibroblasts [nTPM]":"20.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"32.5","Single Cell Type RNA - granulocytes [nTPM]":"14.0","Single Cell Type RNA - Granulosa cells [nTPM]":"15.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"24.7","Single Cell Type RNA - Hepatocytes [nTPM]":"7.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"50.7","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.5","Single Cell Type RNA - Ionocytes [nTPM]":"42.7","Single Cell Type RNA - Kupffer cells [nTPM]":"45.6","Single Cell Type RNA - Langerhans cells [nTPM]":"107.9","Single Cell Type RNA - Late spermatids [nTPM]":"10.3","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"62.6","Single Cell Type RNA - Melanocytes [nTPM]":"33.8","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"79.2","Single Cell Type RNA - Muller glia cells [nTPM]":"25.9","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"28.3","Single Cell Type RNA - Paneth cells [nTPM]":"15.4","Single Cell Type RNA - Peritubular cells [nTPM]":"15.8","Single Cell Type RNA - Plasma cells [nTPM]":"13.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"48.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"70.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.9","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.1","Single Cell Type RNA - Spermatocytes [nTPM]":"12.7","Single Cell Type RNA - Spermatogonia [nTPM]":"23.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"30.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"33.5","Single Cell Type RNA - T-cells [nTPM]":"32.7","Single Cell Type RNA - Theca cells [nTPM]":"20.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.0","Single Cell Type RNA - Urothelial cells [nTPM]":"79.2"},{"Gene":"RLIM","Gene synonym":["MGC15161","NY-REN-43","RNF12"],"Ensembl":"ENSG00000131263","Gene description":"Ring finger protein, LIM domain interacting","Uniprot":["Q9NVW2"],"Chromosome":"X","Position":"74582976-74614624","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018895"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA018895":"AB_1856323"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.04e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Tissue RNA - adipose tissue [nTPM]":"11.3","Tissue RNA - adrenal gland [nTPM]":"11.8","Tissue RNA - amygdala [nTPM]":"10.6","Tissue RNA - appendix [nTPM]":"10.4","Tissue RNA - basal ganglia [nTPM]":"11.7","Tissue RNA - bone marrow [nTPM]":"41.2","Tissue RNA - breast [nTPM]":"10.5","Tissue RNA - cerebellum [nTPM]":"5.9","Tissue RNA - cerebral cortex [nTPM]":"9.9","Tissue RNA - cervix [nTPM]":"10.0","Tissue RNA - choroid plexus [nTPM]":"10.0","Tissue RNA - colon [nTPM]":"6.8","Tissue RNA - duodenum [nTPM]":"5.9","Tissue RNA - endometrium 1 [nTPM]":"9.5","Tissue RNA - epididymis [nTPM]":"5.6","Tissue RNA - esophagus [nTPM]":"8.7","Tissue RNA - fallopian tube [nTPM]":"8.4","Tissue RNA - gallbladder [nTPM]":"9.6","Tissue RNA - heart muscle [nTPM]":"8.8","Tissue RNA - hippocampal formation [nTPM]":"11.2","Tissue RNA - hypothalamus [nTPM]":"15.1","Tissue RNA - kidney [nTPM]":"10.0","Tissue RNA - liver [nTPM]":"8.3","Tissue RNA - lung [nTPM]":"12.1","Tissue RNA - lymph node [nTPM]":"8.9","Tissue RNA - medulla oblongata [nTPM]":"8.5","Tissue RNA - midbrain [nTPM]":"10.3","Tissue RNA - ovary [nTPM]":"10.6","Tissue RNA - pancreas [nTPM]":"7.5","Tissue RNA - parathyroid gland [nTPM]":"11.7","Tissue RNA - pituitary gland [nTPM]":"10.3","Tissue RNA - placenta [nTPM]":"9.8","Tissue RNA - pons [nTPM]":"10.3","Tissue RNA - prostate [nTPM]":"9.8","Tissue RNA - rectum [nTPM]":"6.6","Tissue RNA - retina [nTPM]":"10.7","Tissue RNA - salivary gland [nTPM]":"7.4","Tissue RNA - seminal vesicle [nTPM]":"7.1","Tissue RNA - skeletal muscle [nTPM]":"9.6","Tissue RNA - skin 1 [nTPM]":"9.4","Tissue RNA - small intestine [nTPM]":"6.1","Tissue RNA - smooth muscle [nTPM]":"9.3","Tissue RNA - spinal cord [nTPM]":"7.3","Tissue RNA - spleen [nTPM]":"9.3","Tissue RNA - stomach 1 [nTPM]":"7.4","Tissue RNA - testis [nTPM]":"6.5","Tissue RNA - thalamus [nTPM]":"12.6","Tissue RNA - thymus [nTPM]":"11.0","Tissue RNA - thyroid gland [nTPM]":"11.7","Tissue RNA - tongue [nTPM]":"8.6","Tissue RNA - tonsil [nTPM]":"9.5","Tissue RNA - urinary bladder [nTPM]":"8.5","Tissue RNA - vagina [nTPM]":"8.0","Tissue RNA - white matter [nTPM]":"8.2","Cell RNA - A-431 [nTPM]":"23.7","Cell RNA - A549 [nTPM]":"24.2","Cell RNA - AF22 [nTPM]":"22.8","Cell RNA - AN3-CA [nTPM]":"18.7","Cell RNA - ASC diff [nTPM]":"20.1","Cell RNA - ASC TERT1 [nTPM]":"22.5","Cell RNA - BEWO [nTPM]":"22.4","Cell RNA - BJ [nTPM]":"22.4","Cell RNA - BJ hTERT+ [nTPM]":"26.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.4","Cell RNA - CACO-2 [nTPM]":"18.9","Cell RNA - CAPAN-2 [nTPM]":"24.4","Cell RNA - Daudi [nTPM]":"12.8","Cell RNA - EFO-21 [nTPM]":"25.4","Cell RNA - fHDF\/TERT166 [nTPM]":"28.6","Cell RNA - GAMG [nTPM]":"26.7","Cell RNA - HaCaT [nTPM]":"19.9","Cell RNA - HAP1 [nTPM]":"45.9","Cell RNA - HBEC3-KT [nTPM]":"26.7","Cell RNA - HBF TERT88 [nTPM]":"30.1","Cell RNA - HDLM-2 [nTPM]":"11.7","Cell RNA - HEK 293 [nTPM]":"23.9","Cell RNA - HEL [nTPM]":"22.7","Cell RNA - HeLa [nTPM]":"43.2","Cell RNA - Hep G2 [nTPM]":"10.7","Cell RNA - HHSteC [nTPM]":"17.4","Cell RNA - HL-60 [nTPM]":"34.6","Cell RNA - HMC-1 [nTPM]":"38.6","Cell RNA - HSkMC [nTPM]":"21.7","Cell RNA - hTCEpi [nTPM]":"14.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"28.2","Cell RNA - hTERT-HME1 [nTPM]":"46.5","Cell RNA - hTERT-RPE1 [nTPM]":"15.6","Cell RNA - HUVEC TERT2 [nTPM]":"23.3","Cell RNA - JURKAT [nTPM]":"20.9","Cell RNA - K-562 [nTPM]":"19.9","Cell RNA - Karpas-707 [nTPM]":"22.9","Cell RNA - LHCN-M2 [nTPM]":"24.6","Cell RNA - MCF7 [nTPM]":"18.1","Cell RNA - MOLT-4 [nTPM]":"26.0","Cell RNA - NB-4 [nTPM]":"16.8","Cell RNA - NTERA-2 [nTPM]":"35.0","Cell RNA - OE19 [nTPM]":"12.9","Cell RNA - PC-3 [nTPM]":"22.5","Cell RNA - REH [nTPM]":"24.3","Cell RNA - RH-30 [nTPM]":"48.0","Cell RNA - RPMI-8226 [nTPM]":"21.5","Cell RNA - RPTEC TERT1 [nTPM]":"16.1","Cell RNA - RT4 [nTPM]":"28.6","Cell RNA - SCLC-21H [nTPM]":"16.4","Cell RNA - SH-SY5Y [nTPM]":"19.5","Cell RNA - SiHa [nTPM]":"42.3","Cell RNA - SK-BR-3 [nTPM]":"19.0","Cell RNA - SK-MEL-30 [nTPM]":"24.5","Cell RNA - SuSa [nTPM]":"20.4","Cell RNA - T-47d [nTPM]":"11.2","Cell RNA - THP-1 [nTPM]":"24.9","Cell RNA - TIME [nTPM]":"31.0","Cell RNA - U-138 MG [nTPM]":"23.4","Cell RNA - U-2 OS [nTPM]":"23.1","Cell RNA - U-2197 [nTPM]":"24.8","Cell RNA - U-251 MG [nTPM]":"19.6","Cell RNA - U-266\/70 [nTPM]":"12.0","Cell RNA - U-266\/84 [nTPM]":"24.6","Cell RNA - U-698 [nTPM]":"20.3","Cell RNA - U-87 MG [nTPM]":"25.5","Cell RNA - U-937 [nTPM]":"33.1","Cell RNA - WM-115 [nTPM]":"23.2","Blood RNA - basophil [nTPM]":"22.8","Blood RNA - classical monocyte [nTPM]":"6.0","Blood RNA - eosinophil [nTPM]":"5.9","Blood RNA - gdT-cell [nTPM]":"3.1","Blood RNA - intermediate monocyte [nTPM]":"7.5","Blood RNA - MAIT T-cell [nTPM]":"3.1","Blood RNA - memory B-cell [nTPM]":"3.0","Blood RNA - memory CD4 T-cell [nTPM]":"3.9","Blood RNA - memory CD8 T-cell [nTPM]":"3.8","Blood RNA - myeloid DC [nTPM]":"4.9","Blood RNA - naive B-cell [nTPM]":"3.3","Blood RNA - naive CD4 T-cell [nTPM]":"4.2","Blood RNA - naive CD8 T-cell [nTPM]":"3.8","Blood RNA - neutrophil [nTPM]":"11.5","Blood RNA - NK-cell [nTPM]":"5.3","Blood RNA - non-classical monocyte [nTPM]":"5.6","Blood RNA - plasmacytoid DC [nTPM]":"2.6","Blood RNA - T-reg [nTPM]":"4.8","Blood RNA - total PBMC [nTPM]":"3.2","Brain RNA - amygdala [nTPM]":"10.6","Brain RNA - basal ganglia [nTPM]":"11.7","Brain RNA - cerebellum [nTPM]":"5.9","Brain RNA - cerebral cortex [nTPM]":"9.9","Brain RNA - hippocampal formation [nTPM]":"11.2","Brain RNA - hypothalamus [nTPM]":"15.1","Brain RNA - medulla oblongata [nTPM]":"8.5","Brain RNA - midbrain [nTPM]":"10.3","Brain RNA - pons [nTPM]":"10.3","Brain RNA - spinal cord [nTPM]":"7.3","Brain RNA - thalamus [nTPM]":"12.6","Brain RNA - white matter [nTPM]":"8.2","Single Cell Type RNA - Adipocytes [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.0","Single Cell Type RNA - Astrocytes [nTPM]":"13.4","Single Cell Type RNA - B-cells [nTPM]":"22.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"35.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"29.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.3","Single Cell Type RNA - Bipolar cells [nTPM]":"13.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"30.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"20.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.3","Single Cell Type RNA - dendritic cells [nTPM]":"27.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"13.7","Single Cell Type RNA - Early spermatids [nTPM]":"7.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"32.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"35.3","Single Cell Type RNA - Endothelial cells [nTPM]":"30.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"23.2","Single Cell Type RNA - Erythroid cells [nTPM]":"12.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.5","Single Cell Type RNA - Fibroblasts [nTPM]":"27.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"27.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"41.0","Single Cell Type RNA - granulocytes [nTPM]":"38.0","Single Cell Type RNA - Granulosa cells [nTPM]":"24.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.0","Single Cell Type RNA - Hepatocytes [nTPM]":"14.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.2","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.6","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"20.7","Single Cell Type RNA - Langerhans cells [nTPM]":"34.1","Single Cell Type RNA - Late spermatids [nTPM]":"4.4","Single Cell Type RNA - Leydig cells [nTPM]":"9.9","Single Cell Type RNA - Macrophages [nTPM]":"29.1","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"12.7","Single Cell Type RNA - Muller glia cells [nTPM]":"13.2","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.8","Single Cell Type RNA - Paneth cells [nTPM]":"8.5","Single Cell Type RNA - Peritubular cells [nTPM]":"18.8","Single Cell Type RNA - Plasma cells [nTPM]":"16.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"25.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"25.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"31.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"24.1","Single Cell Type RNA - Spermatocytes [nTPM]":"9.7","Single Cell Type RNA - Spermatogonia [nTPM]":"18.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"38.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"26.3","Single Cell Type RNA - T-cells [nTPM]":"22.0","Single Cell Type RNA - Theca cells [nTPM]":"19.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.4","Single Cell Type RNA - Urothelial cells [nTPM]":"37.2"},{"Gene":"RNASEH1","Gene synonym":[],"Ensembl":"ENSG00000171865","Gene description":"Ribonuclease H1","Uniprot":["O60930"],"Chromosome":"2","Position":"3541430-3558333","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Endonuclease","Hydrolase","Nuclease"],"Disease involvement":["Disease variant","Primary mitochondrial disease","Progressive external ophthalmoplegia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034817","HPA043037"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA034817":null,"HPA043037":"AB_2678280"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.81e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.83e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-3"},"Tissue RNA - adipose tissue [nTPM]":"10.6","Tissue RNA - adrenal gland [nTPM]":"8.7","Tissue RNA - amygdala [nTPM]":"9.7","Tissue RNA - appendix [nTPM]":"9.5","Tissue RNA - basal ganglia [nTPM]":"10.6","Tissue RNA - bone marrow [nTPM]":"11.4","Tissue RNA - breast [nTPM]":"9.7","Tissue RNA - cerebellum [nTPM]":"8.2","Tissue RNA - cerebral cortex [nTPM]":"12.3","Tissue RNA - cervix [nTPM]":"8.5","Tissue RNA - choroid plexus [nTPM]":"6.8","Tissue RNA - colon [nTPM]":"7.8","Tissue RNA - duodenum [nTPM]":"7.2","Tissue RNA - endometrium 1 [nTPM]":"11.7","Tissue RNA - epididymis [nTPM]":"11.3","Tissue RNA - esophagus [nTPM]":"9.6","Tissue RNA - fallopian tube [nTPM]":"7.8","Tissue RNA - gallbladder [nTPM]":"7.5","Tissue RNA - heart muscle [nTPM]":"13.0","Tissue RNA - hippocampal formation [nTPM]":"11.1","Tissue RNA - hypothalamus [nTPM]":"11.2","Tissue RNA - kidney [nTPM]":"7.1","Tissue RNA - liver [nTPM]":"8.1","Tissue RNA - lung [nTPM]":"7.9","Tissue RNA - lymph node [nTPM]":"10.2","Tissue RNA - medulla oblongata [nTPM]":"10.1","Tissue RNA - midbrain [nTPM]":"9.1","Tissue RNA - ovary [nTPM]":"8.2","Tissue RNA - pancreas [nTPM]":"8.7","Tissue RNA - parathyroid gland [nTPM]":"9.1","Tissue RNA - pituitary gland [nTPM]":"3.3","Tissue RNA - placenta [nTPM]":"7.9","Tissue RNA - pons [nTPM]":"10.1","Tissue RNA - prostate [nTPM]":"9.3","Tissue RNA - rectum [nTPM]":"9.5","Tissue RNA - retina [nTPM]":"8.7","Tissue RNA - salivary gland [nTPM]":"7.7","Tissue RNA - seminal vesicle [nTPM]":"11.8","Tissue RNA - skeletal muscle [nTPM]":"15.3","Tissue RNA - skin 1 [nTPM]":"9.9","Tissue RNA - small intestine [nTPM]":"7.8","Tissue RNA - smooth muscle [nTPM]":"13.3","Tissue RNA - spinal cord [nTPM]":"9.2","Tissue RNA - spleen [nTPM]":"9.0","Tissue RNA - stomach 1 [nTPM]":"6.9","Tissue RNA - testis [nTPM]":"7.0","Tissue RNA - thalamus [nTPM]":"11.7","Tissue RNA - thymus [nTPM]":"10.3","Tissue RNA - thyroid gland [nTPM]":"9.5","Tissue RNA - tongue [nTPM]":"15.0","Tissue RNA - tonsil [nTPM]":"10.9","Tissue RNA - urinary bladder [nTPM]":"8.5","Tissue RNA - vagina [nTPM]":"4.7","Tissue RNA - white matter [nTPM]":"10.5","Cell RNA - A-431 [nTPM]":"11.9","Cell RNA - A549 [nTPM]":"21.4","Cell RNA - AF22 [nTPM]":"22.1","Cell RNA - AN3-CA [nTPM]":"22.5","Cell RNA - ASC diff [nTPM]":"24.9","Cell RNA - ASC TERT1 [nTPM]":"23.2","Cell RNA - BEWO [nTPM]":"17.2","Cell RNA - BJ [nTPM]":"29.0","Cell RNA - BJ hTERT+ [nTPM]":"30.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.5","Cell RNA - CACO-2 [nTPM]":"19.4","Cell RNA - CAPAN-2 [nTPM]":"13.0","Cell RNA - Daudi [nTPM]":"33.6","Cell RNA - EFO-21 [nTPM]":"13.7","Cell RNA - fHDF\/TERT166 [nTPM]":"31.5","Cell RNA - GAMG [nTPM]":"18.8","Cell RNA - HaCaT [nTPM]":"14.7","Cell RNA - HAP1 [nTPM]":"32.6","Cell RNA - HBEC3-KT [nTPM]":"23.2","Cell RNA - HBF TERT88 [nTPM]":"30.9","Cell RNA - HDLM-2 [nTPM]":"12.4","Cell RNA - HEK 293 [nTPM]":"17.5","Cell RNA - HEL [nTPM]":"33.1","Cell RNA - HeLa [nTPM]":"18.9","Cell RNA - Hep G2 [nTPM]":"27.5","Cell RNA - HHSteC [nTPM]":"35.5","Cell RNA - HL-60 [nTPM]":"42.0","Cell RNA - HMC-1 [nTPM]":"23.3","Cell RNA - HSkMC [nTPM]":"23.5","Cell RNA - hTCEpi [nTPM]":"24.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"24.2","Cell RNA - hTERT-HME1 [nTPM]":"29.3","Cell RNA - hTERT-RPE1 [nTPM]":"18.5","Cell RNA - HUVEC TERT2 [nTPM]":"21.5","Cell RNA - JURKAT [nTPM]":"54.8","Cell RNA - K-562 [nTPM]":"33.0","Cell RNA - Karpas-707 [nTPM]":"19.4","Cell RNA - LHCN-M2 [nTPM]":"31.1","Cell RNA - MCF7 [nTPM]":"9.3","Cell RNA - MOLT-4 [nTPM]":"32.7","Cell RNA - NB-4 [nTPM]":"27.3","Cell RNA - NTERA-2 [nTPM]":"34.7","Cell RNA - OE19 [nTPM]":"20.6","Cell RNA - PC-3 [nTPM]":"17.0","Cell RNA - REH [nTPM]":"26.9","Cell RNA - RH-30 [nTPM]":"32.0","Cell RNA - RPMI-8226 [nTPM]":"34.3","Cell RNA - RPTEC TERT1 [nTPM]":"21.0","Cell RNA - RT4 [nTPM]":"19.7","Cell RNA - SCLC-21H [nTPM]":"33.3","Cell RNA - SH-SY5Y [nTPM]":"48.9","Cell RNA - SiHa [nTPM]":"17.8","Cell RNA - SK-BR-3 [nTPM]":"15.9","Cell RNA - SK-MEL-30 [nTPM]":"27.5","Cell RNA - SuSa [nTPM]":"16.7","Cell RNA - T-47d [nTPM]":"10.3","Cell RNA - THP-1 [nTPM]":"22.9","Cell RNA - TIME [nTPM]":"24.8","Cell RNA - U-138 MG [nTPM]":"24.1","Cell RNA - U-2 OS [nTPM]":"11.5","Cell RNA - U-2197 [nTPM]":"24.7","Cell RNA - U-251 MG [nTPM]":"40.7","Cell RNA - U-266\/70 [nTPM]":"36.1","Cell RNA - U-266\/84 [nTPM]":"37.5","Cell RNA - U-698 [nTPM]":"43.9","Cell RNA - U-87 MG [nTPM]":"43.2","Cell RNA - U-937 [nTPM]":"35.1","Cell RNA - WM-115 [nTPM]":"37.5","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"1.3","Blood RNA - gdT-cell [nTPM]":"1.3","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"2.2","Blood RNA - memory B-cell [nTPM]":"1.1","Blood RNA - memory CD4 T-cell [nTPM]":"1.0","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"2.1","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"1.2","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"9.7","Brain RNA - basal ganglia [nTPM]":"10.6","Brain RNA - cerebellum [nTPM]":"8.2","Brain RNA - cerebral cortex [nTPM]":"12.3","Brain RNA - hippocampal formation [nTPM]":"11.1","Brain RNA - hypothalamus [nTPM]":"11.2","Brain RNA - medulla oblongata [nTPM]":"10.1","Brain RNA - midbrain [nTPM]":"9.1","Brain RNA - pons [nTPM]":"10.1","Brain RNA - spinal cord [nTPM]":"9.2","Brain RNA - thalamus [nTPM]":"11.7","Brain RNA - white matter [nTPM]":"10.5","Single Cell Type RNA - Adipocytes [nTPM]":"15.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.9","Single Cell Type RNA - Astrocytes [nTPM]":"9.1","Single Cell Type RNA - B-cells [nTPM]":"30.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"26.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"25.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"14.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"32.7","Single Cell Type RNA - dendritic cells [nTPM]":"25.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"37.2","Single Cell Type RNA - Ductal cells [nTPM]":"44.3","Single Cell Type RNA - Early spermatids [nTPM]":"5.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.8","Single Cell Type RNA - Endothelial cells [nTPM]":"20.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.0","Single Cell Type RNA - Erythroid cells [nTPM]":"13.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"48.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"44.3","Single Cell Type RNA - Fibroblasts [nTPM]":"20.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.0","Single Cell Type RNA - granulocytes [nTPM]":"27.3","Single Cell Type RNA - Granulosa cells [nTPM]":"17.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.8","Single Cell Type RNA - Hepatocytes [nTPM]":"18.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.8","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.4","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"18.8","Single Cell Type RNA - Langerhans cells [nTPM]":"8.9","Single Cell Type RNA - Late spermatids [nTPM]":"3.4","Single Cell Type RNA - Leydig cells [nTPM]":"13.7","Single Cell Type RNA - Macrophages [nTPM]":"16.2","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"32.3","Single Cell Type RNA - Muller glia cells [nTPM]":"17.5","Single Cell Type RNA - NK-cells [nTPM]":"30.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"48.3","Single Cell Type RNA - Paneth cells [nTPM]":"9.9","Single Cell Type RNA - Peritubular cells [nTPM]":"26.4","Single Cell Type RNA - Plasma cells [nTPM]":"41.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"50.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"16.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"28.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.4","Single Cell Type RNA - Spermatocytes [nTPM]":"21.0","Single Cell Type RNA - Spermatogonia [nTPM]":"27.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"36.5","Single Cell Type RNA - T-cells [nTPM]":"18.9","Single Cell Type RNA - Theca cells [nTPM]":"27.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.9","Single Cell Type RNA - Urothelial cells [nTPM]":"37.9"},{"Gene":"RNASEH2A","Gene synonym":["AGS4","RNASEHI","RNHIA","RNHL"],"Ensembl":"ENSG00000104889","Gene description":"Ribonuclease H2 subunit A","Uniprot":["O75792"],"Chromosome":"19","Position":"12806584-12813640","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Endonuclease","Hydrolase","Nuclease"],"Disease involvement":["Aicardi-Goutieres syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"62.3","Extravillous trophoblasts":"117.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042692"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA042692":"AB_10793981"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.18e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.18e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.72e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.22e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.29e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.9","Tissue RNA - adrenal gland [nTPM]":"6.8","Tissue RNA - amygdala [nTPM]":"7.0","Tissue RNA - appendix [nTPM]":"11.8","Tissue RNA - basal ganglia [nTPM]":"7.2","Tissue RNA - bone marrow [nTPM]":"28.0","Tissue RNA - breast [nTPM]":"9.0","Tissue RNA - cerebellum [nTPM]":"10.4","Tissue RNA - cerebral cortex [nTPM]":"9.1","Tissue RNA - cervix [nTPM]":"10.8","Tissue RNA - choroid plexus [nTPM]":"6.2","Tissue RNA - colon [nTPM]":"10.5","Tissue RNA - duodenum [nTPM]":"10.3","Tissue RNA - endometrium 1 [nTPM]":"8.5","Tissue RNA - epididymis [nTPM]":"4.9","Tissue RNA - esophagus [nTPM]":"18.3","Tissue RNA - fallopian tube [nTPM]":"10.6","Tissue RNA - gallbladder [nTPM]":"4.9","Tissue RNA - heart muscle [nTPM]":"7.6","Tissue RNA - hippocampal formation [nTPM]":"7.2","Tissue RNA - hypothalamus [nTPM]":"6.1","Tissue RNA - kidney [nTPM]":"7.4","Tissue RNA - liver [nTPM]":"6.9","Tissue RNA - lung [nTPM]":"7.3","Tissue RNA - lymph node [nTPM]":"17.1","Tissue RNA - medulla oblongata [nTPM]":"7.3","Tissue RNA - midbrain [nTPM]":"6.5","Tissue RNA - ovary [nTPM]":"8.9","Tissue RNA - pancreas [nTPM]":"9.2","Tissue RNA - parathyroid gland [nTPM]":"5.3","Tissue RNA - pituitary gland [nTPM]":"5.4","Tissue RNA - placenta [nTPM]":"10.4","Tissue RNA - pons [nTPM]":"7.4","Tissue RNA - prostate [nTPM]":"6.0","Tissue RNA - rectum [nTPM]":"10.7","Tissue RNA - retina [nTPM]":"8.4","Tissue RNA - salivary gland [nTPM]":"8.6","Tissue RNA - seminal vesicle [nTPM]":"5.0","Tissue RNA - skeletal muscle [nTPM]":"8.9","Tissue RNA - skin 1 [nTPM]":"13.9","Tissue RNA - small intestine [nTPM]":"10.0","Tissue RNA - smooth muscle [nTPM]":"8.2","Tissue RNA - spinal cord [nTPM]":"6.0","Tissue RNA - spleen [nTPM]":"14.5","Tissue RNA - stomach 1 [nTPM]":"9.4","Tissue RNA - testis [nTPM]":"19.8","Tissue RNA - thalamus [nTPM]":"6.8","Tissue RNA - thymus [nTPM]":"24.4","Tissue RNA - thyroid gland [nTPM]":"7.5","Tissue RNA - tongue [nTPM]":"6.6","Tissue RNA - tonsil [nTPM]":"18.7","Tissue RNA - urinary bladder [nTPM]":"8.2","Tissue RNA - vagina [nTPM]":"10.8","Tissue RNA - white matter [nTPM]":"9.5","Cell RNA - A-431 [nTPM]":"130.0","Cell RNA - A549 [nTPM]":"103.8","Cell RNA - AF22 [nTPM]":"94.8","Cell RNA - AN3-CA [nTPM]":"75.7","Cell RNA - ASC diff [nTPM]":"12.3","Cell RNA - ASC TERT1 [nTPM]":"23.4","Cell RNA - BEWO [nTPM]":"76.2","Cell RNA - BJ [nTPM]":"68.4","Cell RNA - BJ hTERT+ [nTPM]":"40.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"126.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"136.0","Cell RNA - CACO-2 [nTPM]":"76.2","Cell RNA - CAPAN-2 [nTPM]":"58.7","Cell RNA - Daudi [nTPM]":"126.9","Cell RNA - EFO-21 [nTPM]":"106.2","Cell RNA - fHDF\/TERT166 [nTPM]":"36.6","Cell RNA - GAMG [nTPM]":"59.6","Cell RNA - HaCaT [nTPM]":"79.4","Cell RNA - HAP1 [nTPM]":"82.6","Cell RNA - HBEC3-KT [nTPM]":"89.2","Cell RNA - HBF TERT88 [nTPM]":"83.5","Cell RNA - HDLM-2 [nTPM]":"82.7","Cell RNA - HEK 293 [nTPM]":"118.1","Cell RNA - HEL [nTPM]":"67.7","Cell RNA - HeLa [nTPM]":"112.9","Cell RNA - Hep G2 [nTPM]":"89.9","Cell RNA - HHSteC [nTPM]":"7.1","Cell RNA - HL-60 [nTPM]":"70.6","Cell RNA - HMC-1 [nTPM]":"60.5","Cell RNA - HSkMC [nTPM]":"10.4","Cell RNA - hTCEpi [nTPM]":"19.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"110.7","Cell RNA - hTERT-HME1 [nTPM]":"43.9","Cell RNA - hTERT-RPE1 [nTPM]":"21.4","Cell RNA - HUVEC TERT2 [nTPM]":"47.3","Cell RNA - JURKAT [nTPM]":"114.8","Cell RNA - K-562 [nTPM]":"91.2","Cell RNA - Karpas-707 [nTPM]":"46.8","Cell RNA - LHCN-M2 [nTPM]":"82.0","Cell RNA - MCF7 [nTPM]":"251.4","Cell RNA - MOLT-4 [nTPM]":"132.8","Cell RNA - NB-4 [nTPM]":"83.0","Cell RNA - NTERA-2 [nTPM]":"56.4","Cell RNA - OE19 [nTPM]":"79.1","Cell RNA - PC-3 [nTPM]":"167.4","Cell RNA - REH [nTPM]":"146.1","Cell RNA - RH-30 [nTPM]":"102.0","Cell RNA - RPMI-8226 [nTPM]":"113.7","Cell RNA - RPTEC TERT1 [nTPM]":"39.6","Cell RNA - RT4 [nTPM]":"63.8","Cell RNA - SCLC-21H [nTPM]":"119.8","Cell RNA - SH-SY5Y [nTPM]":"76.7","Cell RNA - SiHa [nTPM]":"67.0","Cell RNA - SK-BR-3 [nTPM]":"39.8","Cell RNA - SK-MEL-30 [nTPM]":"46.7","Cell RNA - SuSa [nTPM]":"39.8","Cell RNA - T-47d [nTPM]":"76.1","Cell RNA - THP-1 [nTPM]":"78.4","Cell RNA - TIME [nTPM]":"29.3","Cell RNA - U-138 MG [nTPM]":"129.2","Cell RNA - U-2 OS [nTPM]":"55.7","Cell RNA - U-2197 [nTPM]":"197.0","Cell RNA - U-251 MG [nTPM]":"126.1","Cell RNA - U-266\/70 [nTPM]":"97.6","Cell RNA - U-266\/84 [nTPM]":"130.3","Cell RNA - U-698 [nTPM]":"108.5","Cell RNA - U-87 MG [nTPM]":"77.4","Cell RNA - U-937 [nTPM]":"129.4","Cell RNA - WM-115 [nTPM]":"105.5","Blood RNA - basophil [nTPM]":"9.4","Blood RNA - classical monocyte [nTPM]":"19.1","Blood RNA - eosinophil [nTPM]":"17.2","Blood RNA - gdT-cell [nTPM]":"23.9","Blood RNA - intermediate monocyte [nTPM]":"27.6","Blood RNA - MAIT T-cell [nTPM]":"23.3","Blood RNA - memory B-cell [nTPM]":"36.8","Blood RNA - memory CD4 T-cell [nTPM]":"19.6","Blood RNA - memory CD8 T-cell [nTPM]":"22.5","Blood RNA - myeloid DC [nTPM]":"19.0","Blood RNA - naive B-cell [nTPM]":"36.3","Blood RNA - naive CD4 T-cell [nTPM]":"15.9","Blood RNA - naive CD8 T-cell [nTPM]":"19.6","Blood RNA - neutrophil [nTPM]":"4.4","Blood RNA - NK-cell [nTPM]":"44.8","Blood RNA - non-classical monocyte [nTPM]":"27.7","Blood RNA - plasmacytoid DC [nTPM]":"21.0","Blood RNA - T-reg [nTPM]":"25.8","Blood RNA - total PBMC [nTPM]":"19.1","Brain RNA - amygdala [nTPM]":"7.0","Brain RNA - basal ganglia [nTPM]":"7.2","Brain RNA - cerebellum [nTPM]":"10.4","Brain RNA - cerebral cortex [nTPM]":"9.1","Brain RNA - hippocampal formation [nTPM]":"7.2","Brain RNA - hypothalamus [nTPM]":"6.1","Brain RNA - medulla oblongata [nTPM]":"7.3","Brain RNA - midbrain [nTPM]":"6.5","Brain RNA - pons [nTPM]":"7.4","Brain RNA - spinal cord [nTPM]":"6.0","Brain RNA - thalamus [nTPM]":"6.8","Brain RNA - white matter [nTPM]":"9.5","Single Cell Type RNA - Adipocytes [nTPM]":"5.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.6","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"15.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"16.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"7.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"62.3","Single Cell Type RNA - dendritic cells [nTPM]":"9.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.4","Single Cell Type RNA - Early spermatids [nTPM]":"16.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.6","Single Cell Type RNA - Endothelial cells [nTPM]":"9.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"38.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"117.4","Single Cell Type RNA - Fibroblasts [nTPM]":"10.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.1","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"2.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"4.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"48.9","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.9","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"9.1","Single Cell Type RNA - Langerhans cells [nTPM]":"13.2","Single Cell Type RNA - Late spermatids [nTPM]":"18.8","Single Cell Type RNA - Leydig cells [nTPM]":"8.4","Single Cell Type RNA - Macrophages [nTPM]":"9.3","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"8.5","Single Cell Type RNA - Muller glia cells [nTPM]":"10.4","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.1","Single Cell Type RNA - Paneth cells [nTPM]":"6.8","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"33.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.8","Single Cell Type RNA - Spermatocytes [nTPM]":"51.2","Single Cell Type RNA - Spermatogonia [nTPM]":"44.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.7","Single Cell Type RNA - T-cells [nTPM]":"10.2","Single Cell Type RNA - Theca cells [nTPM]":"0.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.8","Single Cell Type RNA - Urothelial cells [nTPM]":"16.1"},{"Gene":"RNASEL","Gene synonym":["PRCA1","RNS4"],"Ensembl":"ENSG00000135828","Gene description":"Ribonuclease L","Uniprot":["Q05823"],"Chromosome":"1","Position":"182573634-182589256","Protein class":["Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Antiviral defense"],"Molecular function":["Endonuclease","Hydrolase","Nuclease","RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002633","CAB010906"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB010906":"AB_477444","HPA002633":"AB_1856314"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.6","Tissue RNA - adrenal gland [nTPM]":"6.4","Tissue RNA - amygdala [nTPM]":"3.2","Tissue RNA - appendix [nTPM]":"8.8","Tissue RNA - basal ganglia [nTPM]":"3.5","Tissue RNA - bone marrow [nTPM]":"3.6","Tissue RNA - breast [nTPM]":"5.9","Tissue RNA - cerebellum [nTPM]":"3.4","Tissue RNA - cerebral cortex [nTPM]":"3.9","Tissue RNA - cervix [nTPM]":"6.6","Tissue RNA - choroid plexus [nTPM]":"3.7","Tissue RNA - colon [nTPM]":"8.1","Tissue RNA - duodenum [nTPM]":"7.0","Tissue RNA - endometrium 1 [nTPM]":"6.5","Tissue RNA - epididymis [nTPM]":"9.6","Tissue RNA - esophagus [nTPM]":"6.2","Tissue RNA - fallopian tube [nTPM]":"5.2","Tissue RNA - gallbladder [nTPM]":"6.9","Tissue RNA - heart muscle [nTPM]":"3.4","Tissue RNA - hippocampal formation [nTPM]":"2.9","Tissue RNA - hypothalamus [nTPM]":"3.4","Tissue RNA - kidney [nTPM]":"6.2","Tissue RNA - liver [nTPM]":"3.5","Tissue RNA - lung [nTPM]":"6.9","Tissue RNA - lymph node [nTPM]":"9.6","Tissue RNA - medulla oblongata [nTPM]":"3.4","Tissue RNA - midbrain [nTPM]":"3.5","Tissue RNA - ovary [nTPM]":"11.3","Tissue RNA - pancreas [nTPM]":"3.1","Tissue RNA - parathyroid gland [nTPM]":"7.9","Tissue RNA - pituitary gland [nTPM]":"5.4","Tissue RNA - placenta [nTPM]":"6.9","Tissue RNA - pons [nTPM]":"3.6","Tissue RNA - prostate [nTPM]":"7.2","Tissue RNA - rectum [nTPM]":"9.0","Tissue RNA - retina [nTPM]":"5.7","Tissue RNA - salivary gland [nTPM]":"5.0","Tissue RNA - seminal vesicle [nTPM]":"8.3","Tissue RNA - skeletal muscle [nTPM]":"2.0","Tissue RNA - skin 1 [nTPM]":"5.4","Tissue RNA - small intestine [nTPM]":"8.0","Tissue RNA - smooth muscle [nTPM]":"7.1","Tissue RNA - spinal cord [nTPM]":"2.8","Tissue RNA - spleen [nTPM]":"8.9","Tissue RNA - stomach 1 [nTPM]":"7.8","Tissue RNA - testis [nTPM]":"2.2","Tissue RNA - thalamus [nTPM]":"3.6","Tissue RNA - thymus [nTPM]":"8.0","Tissue RNA - thyroid gland [nTPM]":"9.1","Tissue RNA - tongue [nTPM]":"4.5","Tissue RNA - tonsil [nTPM]":"9.9","Tissue RNA - urinary bladder [nTPM]":"6.0","Tissue RNA - vagina [nTPM]":"6.3","Tissue RNA - white matter [nTPM]":"3.3","Cell RNA - A-431 [nTPM]":"2.6","Cell RNA - A549 [nTPM]":"3.6","Cell RNA - AF22 [nTPM]":"1.5","Cell RNA - AN3-CA [nTPM]":"0.6","Cell RNA - ASC diff [nTPM]":"7.9","Cell RNA - ASC TERT1 [nTPM]":"13.7","Cell RNA - BEWO [nTPM]":"2.8","Cell RNA - BJ [nTPM]":"4.9","Cell RNA - BJ hTERT+ [nTPM]":"6.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.5","Cell RNA - CACO-2 [nTPM]":"2.1","Cell RNA - CAPAN-2 [nTPM]":"5.6","Cell RNA - Daudi [nTPM]":"5.6","Cell RNA - EFO-21 [nTPM]":"8.4","Cell RNA - fHDF\/TERT166 [nTPM]":"5.6","Cell RNA - GAMG [nTPM]":"2.2","Cell RNA - HaCaT [nTPM]":"4.7","Cell RNA - HAP1 [nTPM]":"3.6","Cell RNA - HBEC3-KT [nTPM]":"5.1","Cell RNA - HBF TERT88 [nTPM]":"1.9","Cell RNA - HDLM-2 [nTPM]":"4.5","Cell RNA - HEK 293 [nTPM]":"3.1","Cell RNA - HEL [nTPM]":"6.6","Cell RNA - HeLa [nTPM]":"1.3","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"4.1","Cell RNA - HL-60 [nTPM]":"12.4","Cell RNA - HMC-1 [nTPM]":"12.5","Cell RNA - HSkMC [nTPM]":"9.8","Cell RNA - hTCEpi [nTPM]":"11.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.6","Cell RNA - hTERT-HME1 [nTPM]":"0.7","Cell RNA - hTERT-RPE1 [nTPM]":"3.1","Cell RNA - HUVEC TERT2 [nTPM]":"2.1","Cell RNA - JURKAT [nTPM]":"8.2","Cell RNA - K-562 [nTPM]":"2.4","Cell RNA - Karpas-707 [nTPM]":"4.2","Cell RNA - LHCN-M2 [nTPM]":"4.3","Cell RNA - MCF7 [nTPM]":"3.8","Cell RNA - MOLT-4 [nTPM]":"3.6","Cell RNA - NB-4 [nTPM]":"5.1","Cell RNA - NTERA-2 [nTPM]":"1.2","Cell RNA - OE19 [nTPM]":"8.4","Cell RNA - PC-3 [nTPM]":"1.0","Cell RNA - REH [nTPM]":"5.3","Cell RNA - RH-30 [nTPM]":"1.2","Cell RNA - RPMI-8226 [nTPM]":"2.9","Cell RNA - RPTEC TERT1 [nTPM]":"5.2","Cell RNA - RT4 [nTPM]":"3.4","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"4.4","Cell RNA - SK-BR-3 [nTPM]":"5.3","Cell RNA - SK-MEL-30 [nTPM]":"4.3","Cell RNA - SuSa [nTPM]":"3.9","Cell RNA - T-47d [nTPM]":"5.4","Cell RNA - THP-1 [nTPM]":"13.6","Cell RNA - TIME [nTPM]":"2.8","Cell RNA - U-138 MG [nTPM]":"2.5","Cell RNA - U-2 OS [nTPM]":"2.0","Cell RNA - U-2197 [nTPM]":"2.7","Cell RNA - U-251 MG [nTPM]":"2.7","Cell RNA - U-266\/70 [nTPM]":"3.7","Cell RNA - U-266\/84 [nTPM]":"1.3","Cell RNA - U-698 [nTPM]":"0.7","Cell RNA - U-87 MG [nTPM]":"4.0","Cell RNA - U-937 [nTPM]":"7.5","Cell RNA - WM-115 [nTPM]":"3.8","Blood RNA - basophil [nTPM]":"41.7","Blood RNA - classical monocyte [nTPM]":"14.8","Blood RNA - eosinophil [nTPM]":"53.1","Blood RNA - gdT-cell [nTPM]":"9.4","Blood RNA - intermediate monocyte [nTPM]":"15.8","Blood RNA - MAIT T-cell [nTPM]":"12.4","Blood RNA - memory B-cell [nTPM]":"10.3","Blood RNA - memory CD4 T-cell [nTPM]":"11.1","Blood RNA - memory CD8 T-cell [nTPM]":"10.1","Blood RNA - myeloid DC [nTPM]":"12.4","Blood RNA - naive B-cell [nTPM]":"7.9","Blood RNA - naive CD4 T-cell [nTPM]":"17.3","Blood RNA - naive CD8 T-cell [nTPM]":"12.8","Blood RNA - neutrophil [nTPM]":"55.3","Blood RNA - NK-cell [nTPM]":"10.9","Blood RNA - non-classical monocyte [nTPM]":"30.3","Blood RNA - plasmacytoid DC [nTPM]":"14.7","Blood RNA - T-reg [nTPM]":"10.0","Blood RNA - total PBMC [nTPM]":"10.5","Brain RNA - amygdala [nTPM]":"3.2","Brain RNA - basal ganglia [nTPM]":"3.5","Brain RNA - cerebellum [nTPM]":"3.4","Brain RNA - cerebral cortex [nTPM]":"3.9","Brain RNA - hippocampal formation [nTPM]":"2.9","Brain RNA - hypothalamus [nTPM]":"3.4","Brain RNA - medulla oblongata [nTPM]":"3.4","Brain RNA - midbrain [nTPM]":"3.5","Brain RNA - pons [nTPM]":"3.6","Brain RNA - spinal cord [nTPM]":"2.8","Brain RNA - thalamus [nTPM]":"3.6","Brain RNA - white matter [nTPM]":"3.3","Single Cell Type RNA - Adipocytes [nTPM]":"4.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.2","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"6.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"4.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"9.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.2","Single Cell Type RNA - dendritic cells [nTPM]":"8.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.6","Single Cell Type RNA - Endothelial cells [nTPM]":"5.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"4.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.7","Single Cell Type RNA - Fibroblasts [nTPM]":"6.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.4","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"5.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"1.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.2","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.3","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"9.7","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"5.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"7.3","Single Cell Type RNA - Muller glia cells [nTPM]":"8.7","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.2","Single Cell Type RNA - Paneth cells [nTPM]":"3.2","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"2.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.1","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.6","Single Cell Type RNA - T-cells [nTPM]":"7.5","Single Cell Type RNA - Theca cells [nTPM]":"12.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.0","Single Cell Type RNA - Urothelial cells [nTPM]":"4.6"},{"Gene":"RNASET2","Gene synonym":["bA514O12.3","FLJ10907","RNASE6PL"],"Ensembl":"ENSG00000026297","Gene description":"Ribonuclease T2","Uniprot":["O00584"],"Chromosome":"6","Position":"166922113-166957191","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Immunity","Innate immunity"],"Molecular function":["Endonuclease","Hydrolase","Lyase","Nuclease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"490.2","Glandular and luminal cells":"761.3","Hofbauer cells":"382.2","Kupffer cells":"484.7","Macrophages":"418.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"THP-1":"497.9"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029013","HPA066509"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"15000000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029013":"AB_10602922","HPA066509":"AB_2685682"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.70e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Tissue RNA - adipose tissue [nTPM]":"34.9","Tissue RNA - adrenal gland [nTPM]":"35.0","Tissue RNA - amygdala [nTPM]":"50.1","Tissue RNA - appendix [nTPM]":"68.6","Tissue RNA - basal ganglia [nTPM]":"50.4","Tissue RNA - bone marrow [nTPM]":"124.3","Tissue RNA - breast [nTPM]":"50.2","Tissue RNA - cerebellum [nTPM]":"52.2","Tissue RNA - cerebral cortex [nTPM]":"65.9","Tissue RNA - cervix [nTPM]":"161.5","Tissue RNA - choroid plexus [nTPM]":"52.3","Tissue RNA - colon [nTPM]":"74.0","Tissue RNA - duodenum [nTPM]":"57.6","Tissue RNA - endometrium 1 [nTPM]":"49.1","Tissue RNA - epididymis [nTPM]":"140.7","Tissue RNA - esophagus [nTPM]":"24.8","Tissue RNA - fallopian tube [nTPM]":"134.6","Tissue RNA - gallbladder [nTPM]":"69.6","Tissue RNA - heart muscle [nTPM]":"19.8","Tissue RNA - hippocampal formation [nTPM]":"49.5","Tissue RNA - hypothalamus [nTPM]":"53.5","Tissue RNA - kidney [nTPM]":"31.2","Tissue RNA - liver [nTPM]":"52.4","Tissue RNA - lung [nTPM]":"47.2","Tissue RNA - lymph node [nTPM]":"117.4","Tissue RNA - medulla oblongata [nTPM]":"68.2","Tissue RNA - midbrain [nTPM]":"54.3","Tissue RNA - ovary [nTPM]":"36.2","Tissue RNA - pancreas [nTPM]":"144.7","Tissue RNA - parathyroid gland [nTPM]":"40.7","Tissue RNA - pituitary gland [nTPM]":"26.3","Tissue RNA - placenta [nTPM]":"43.5","Tissue RNA - pons [nTPM]":"66.2","Tissue RNA - prostate [nTPM]":"51.9","Tissue RNA - rectum [nTPM]":"89.9","Tissue RNA - retina [nTPM]":"8.3","Tissue RNA - salivary gland [nTPM]":"112.8","Tissue RNA - seminal vesicle [nTPM]":"94.1","Tissue RNA - skeletal muscle [nTPM]":"7.3","Tissue RNA - skin 1 [nTPM]":"25.4","Tissue RNA - small intestine [nTPM]":"65.4","Tissue RNA - smooth muscle [nTPM]":"27.8","Tissue RNA - spinal cord [nTPM]":"61.9","Tissue RNA - spleen [nTPM]":"195.1","Tissue RNA - stomach 1 [nTPM]":"72.9","Tissue RNA - testis [nTPM]":"13.3","Tissue RNA - thalamus [nTPM]":"59.1","Tissue RNA - thymus [nTPM]":"43.8","Tissue RNA - thyroid gland [nTPM]":"76.7","Tissue RNA - tongue [nTPM]":"12.1","Tissue RNA - tonsil [nTPM]":"86.9","Tissue RNA - urinary bladder [nTPM]":"54.9","Tissue RNA - vagina [nTPM]":"32.2","Tissue RNA - white matter [nTPM]":"79.8","Cell RNA - A-431 [nTPM]":"12.8","Cell RNA - A549 [nTPM]":"14.2","Cell RNA - AF22 [nTPM]":"12.6","Cell RNA - AN3-CA [nTPM]":"37.8","Cell RNA - ASC diff [nTPM]":"57.0","Cell RNA - ASC TERT1 [nTPM]":"40.6","Cell RNA - BEWO [nTPM]":"8.4","Cell RNA - BJ [nTPM]":"15.8","Cell RNA - BJ hTERT+ [nTPM]":"21.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.4","Cell RNA - CACO-2 [nTPM]":"33.7","Cell RNA - CAPAN-2 [nTPM]":"19.9","Cell RNA - Daudi [nTPM]":"11.1","Cell RNA - EFO-21 [nTPM]":"149.8","Cell RNA - fHDF\/TERT166 [nTPM]":"41.3","Cell RNA - GAMG [nTPM]":"16.7","Cell RNA - HaCaT [nTPM]":"41.0","Cell RNA - HAP1 [nTPM]":"20.8","Cell RNA - HBEC3-KT [nTPM]":"18.6","Cell RNA - HBF TERT88 [nTPM]":"4.3","Cell RNA - HDLM-2 [nTPM]":"15.9","Cell RNA - HEK 293 [nTPM]":"35.1","Cell RNA - HEL [nTPM]":"10.2","Cell RNA - HeLa [nTPM]":"20.6","Cell RNA - Hep G2 [nTPM]":"84.6","Cell RNA - HHSteC [nTPM]":"19.1","Cell RNA - HL-60 [nTPM]":"152.7","Cell RNA - HMC-1 [nTPM]":"37.3","Cell RNA - HSkMC [nTPM]":"23.9","Cell RNA - hTCEpi [nTPM]":"33.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.3","Cell RNA - hTERT-HME1 [nTPM]":"2.7","Cell RNA - hTERT-RPE1 [nTPM]":"30.4","Cell RNA - HUVEC TERT2 [nTPM]":"10.1","Cell RNA - JURKAT [nTPM]":"21.7","Cell RNA - K-562 [nTPM]":"20.9","Cell RNA - Karpas-707 [nTPM]":"94.5","Cell RNA - LHCN-M2 [nTPM]":"10.9","Cell RNA - MCF7 [nTPM]":"44.9","Cell RNA - MOLT-4 [nTPM]":"12.6","Cell RNA - NB-4 [nTPM]":"109.5","Cell RNA - NTERA-2 [nTPM]":"6.4","Cell RNA - OE19 [nTPM]":"140.0","Cell RNA - PC-3 [nTPM]":"13.0","Cell RNA - REH [nTPM]":"25.0","Cell RNA - RH-30 [nTPM]":"16.6","Cell RNA - RPMI-8226 [nTPM]":"131.7","Cell RNA - RPTEC TERT1 [nTPM]":"136.3","Cell RNA - RT4 [nTPM]":"9.9","Cell RNA - SCLC-21H [nTPM]":"4.4","Cell RNA - SH-SY5Y [nTPM]":"28.7","Cell RNA - SiHa [nTPM]":"32.0","Cell RNA - SK-BR-3 [nTPM]":"100.4","Cell RNA - SK-MEL-30 [nTPM]":"8.3","Cell RNA - SuSa [nTPM]":"22.3","Cell RNA - T-47d [nTPM]":"13.1","Cell RNA - THP-1 [nTPM]":"497.9","Cell RNA - TIME [nTPM]":"19.3","Cell RNA - U-138 MG [nTPM]":"14.9","Cell RNA - U-2 OS [nTPM]":"9.8","Cell RNA - U-2197 [nTPM]":"43.7","Cell RNA - U-251 MG [nTPM]":"13.5","Cell RNA - U-266\/70 [nTPM]":"15.0","Cell RNA - U-266\/84 [nTPM]":"19.5","Cell RNA - U-698 [nTPM]":"1.4","Cell RNA - U-87 MG [nTPM]":"32.3","Cell RNA - U-937 [nTPM]":"149.2","Cell RNA - WM-115 [nTPM]":"10.3","Blood RNA - basophil [nTPM]":"116.9","Blood RNA - classical monocyte [nTPM]":"185.6","Blood RNA - eosinophil [nTPM]":"674.8","Blood RNA - gdT-cell [nTPM]":"29.1","Blood RNA - intermediate monocyte [nTPM]":"277.0","Blood RNA - MAIT T-cell [nTPM]":"53.4","Blood RNA - memory B-cell [nTPM]":"136.7","Blood RNA - memory CD4 T-cell [nTPM]":"159.9","Blood RNA - memory CD8 T-cell [nTPM]":"72.3","Blood RNA - myeloid DC [nTPM]":"226.4","Blood RNA - naive B-cell [nTPM]":"119.6","Blood RNA - naive CD4 T-cell [nTPM]":"128.4","Blood RNA - naive CD8 T-cell [nTPM]":"41.4","Blood RNA - neutrophil [nTPM]":"438.9","Blood RNA - NK-cell [nTPM]":"30.7","Blood RNA - non-classical monocyte [nTPM]":"368.8","Blood RNA - plasmacytoid DC [nTPM]":"369.3","Blood RNA - T-reg [nTPM]":"90.8","Blood RNA - total PBMC [nTPM]":"179.8","Brain RNA - amygdala [nTPM]":"50.1","Brain RNA - basal ganglia [nTPM]":"50.4","Brain RNA - cerebellum [nTPM]":"52.2","Brain RNA - cerebral cortex [nTPM]":"65.9","Brain RNA - hippocampal formation [nTPM]":"49.5","Brain RNA - hypothalamus [nTPM]":"53.5","Brain RNA - medulla oblongata [nTPM]":"68.2","Brain RNA - midbrain [nTPM]":"54.3","Brain RNA - pons [nTPM]":"66.2","Brain RNA - spinal cord [nTPM]":"61.9","Brain RNA - thalamus [nTPM]":"59.1","Brain RNA - white matter [nTPM]":"79.8","Single Cell Type RNA - Adipocytes [nTPM]":"21.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.3","Single Cell Type RNA - Astrocytes [nTPM]":"10.1","Single Cell Type RNA - B-cells [nTPM]":"270.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"43.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"116.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"45.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"72.3","Single Cell Type RNA - Bipolar cells [nTPM]":"10.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"97.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"95.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"47.1","Single Cell Type RNA - Club cells [nTPM]":"28.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"63.4","Single Cell Type RNA - dendritic cells [nTPM]":"286.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"133.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"59.2","Single Cell Type RNA - Early spermatids [nTPM]":"10.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"490.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"78.9","Single Cell Type RNA - Endothelial cells [nTPM]":"44.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"75.4","Single Cell Type RNA - Erythroid cells [nTPM]":"27.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"27.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"58.8","Single Cell Type RNA - Fibroblasts [nTPM]":"45.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"80.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"761.3","Single Cell Type RNA - granulocytes [nTPM]":"71.7","Single Cell Type RNA - Granulosa cells [nTPM]":"38.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.2","Single Cell Type RNA - Hepatocytes [nTPM]":"20.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"382.2","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"204.0","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"484.7","Single Cell Type RNA - Langerhans cells [nTPM]":"187.7","Single Cell Type RNA - Late spermatids [nTPM]":"11.3","Single Cell Type RNA - Leydig cells [nTPM]":"35.4","Single Cell Type RNA - Macrophages [nTPM]":"418.2","Single Cell Type RNA - Melanocytes [nTPM]":"58.7","Single Cell Type RNA - Microglial cells [nTPM]":"113.4","Single Cell Type RNA - monocytes [nTPM]":"146.1","Single Cell Type RNA - Muller glia cells [nTPM]":"24.4","Single Cell Type RNA - NK-cells [nTPM]":"64.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"74.1","Single Cell Type RNA - Paneth cells [nTPM]":"324.8","Single Cell Type RNA - Peritubular cells [nTPM]":"29.3","Single Cell Type RNA - Plasma cells [nTPM]":"158.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"61.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"178.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.1","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"31.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.6","Single Cell Type RNA - Spermatocytes [nTPM]":"10.0","Single Cell Type RNA - Spermatogonia [nTPM]":"23.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"58.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"34.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"27.8","Single Cell Type RNA - T-cells [nTPM]":"149.2","Single Cell Type RNA - Theca cells [nTPM]":"15.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"193.0","Single Cell Type RNA - Urothelial cells [nTPM]":"103.9"},{"Gene":"RNF113A","Gene synonym":["Cwc24","RNF113","ZNF183"],"Ensembl":"ENSG00000125352","Gene description":"Ring finger protein 113A","Uniprot":["O15541"],"Chromosome":"X","Position":"119870475-119871733","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","mRNA processing","mRNA splicing","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000160","HPA076658"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA000160":"AB_1079821","HPA076658":"AB_2732319"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.49e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.93e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.23e-4"},"Tissue RNA - adipose tissue [nTPM]":"11.0","Tissue RNA - adrenal gland [nTPM]":"9.6","Tissue RNA - amygdala [nTPM]":"11.5","Tissue RNA - appendix [nTPM]":"13.0","Tissue RNA - basal ganglia [nTPM]":"12.1","Tissue RNA - bone marrow [nTPM]":"35.3","Tissue RNA - breast [nTPM]":"10.2","Tissue RNA - cerebellum [nTPM]":"13.0","Tissue RNA - cerebral cortex [nTPM]":"14.4","Tissue RNA - cervix [nTPM]":"10.5","Tissue RNA - choroid plexus [nTPM]":"11.3","Tissue RNA - colon [nTPM]":"11.4","Tissue RNA - duodenum [nTPM]":"13.2","Tissue RNA - endometrium 1 [nTPM]":"9.8","Tissue RNA - epididymis [nTPM]":"9.6","Tissue RNA - esophagus [nTPM]":"11.3","Tissue RNA - fallopian tube [nTPM]":"10.2","Tissue RNA - gallbladder [nTPM]":"8.2","Tissue RNA - heart muscle [nTPM]":"12.7","Tissue RNA - hippocampal formation [nTPM]":"11.7","Tissue RNA - hypothalamus [nTPM]":"13.9","Tissue RNA - kidney [nTPM]":"9.2","Tissue RNA - liver [nTPM]":"17.7","Tissue RNA - lung [nTPM]":"11.0","Tissue RNA - lymph node [nTPM]":"24.7","Tissue RNA - medulla oblongata [nTPM]":"12.7","Tissue RNA - midbrain [nTPM]":"13.0","Tissue RNA - ovary [nTPM]":"13.4","Tissue RNA - pancreas [nTPM]":"19.1","Tissue RNA - parathyroid gland [nTPM]":"9.2","Tissue RNA - pituitary gland [nTPM]":"10.0","Tissue RNA - placenta [nTPM]":"9.0","Tissue RNA - pons [nTPM]":"13.1","Tissue RNA - prostate [nTPM]":"8.9","Tissue RNA - rectum [nTPM]":"9.5","Tissue RNA - retina [nTPM]":"15.6","Tissue RNA - salivary gland [nTPM]":"14.4","Tissue RNA - seminal vesicle [nTPM]":"8.8","Tissue RNA - skeletal muscle [nTPM]":"12.3","Tissue RNA - skin 1 [nTPM]":"17.1","Tissue RNA - small intestine [nTPM]":"17.5","Tissue RNA - smooth muscle [nTPM]":"7.5","Tissue RNA - spinal cord [nTPM]":"11.9","Tissue RNA - spleen [nTPM]":"24.3","Tissue RNA - stomach 1 [nTPM]":"12.1","Tissue RNA - testis [nTPM]":"3.4","Tissue RNA - thalamus [nTPM]":"13.1","Tissue RNA - thymus [nTPM]":"24.7","Tissue RNA - thyroid gland [nTPM]":"9.9","Tissue RNA - tongue [nTPM]":"10.6","Tissue RNA - tonsil [nTPM]":"19.0","Tissue RNA - urinary bladder [nTPM]":"10.8","Tissue RNA - vagina [nTPM]":"10.3","Tissue RNA - white matter [nTPM]":"12.6","Cell RNA - A-431 [nTPM]":"16.9","Cell RNA - A549 [nTPM]":"22.9","Cell RNA - AF22 [nTPM]":"11.0","Cell RNA - AN3-CA [nTPM]":"17.7","Cell RNA - ASC diff [nTPM]":"20.7","Cell RNA - ASC TERT1 [nTPM]":"14.9","Cell RNA - BEWO [nTPM]":"22.3","Cell RNA - BJ [nTPM]":"14.8","Cell RNA - BJ hTERT+ [nTPM]":"25.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.0","Cell RNA - CACO-2 [nTPM]":"19.7","Cell RNA - CAPAN-2 [nTPM]":"14.1","Cell RNA - Daudi [nTPM]":"28.0","Cell RNA - EFO-21 [nTPM]":"28.1","Cell RNA - fHDF\/TERT166 [nTPM]":"13.8","Cell RNA - GAMG [nTPM]":"25.1","Cell RNA - HaCaT [nTPM]":"20.4","Cell RNA - HAP1 [nTPM]":"24.4","Cell RNA - HBEC3-KT [nTPM]":"19.1","Cell RNA - HBF TERT88 [nTPM]":"13.1","Cell RNA - HDLM-2 [nTPM]":"21.9","Cell RNA - HEK 293 [nTPM]":"18.0","Cell RNA - HEL [nTPM]":"17.0","Cell RNA - HeLa [nTPM]":"25.8","Cell RNA - Hep G2 [nTPM]":"23.5","Cell RNA - HHSteC [nTPM]":"28.3","Cell RNA - HL-60 [nTPM]":"33.7","Cell RNA - HMC-1 [nTPM]":"28.3","Cell RNA - HSkMC [nTPM]":"18.4","Cell RNA - hTCEpi [nTPM]":"20.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"17.7","Cell RNA - hTERT-HME1 [nTPM]":"26.0","Cell RNA - hTERT-RPE1 [nTPM]":"20.7","Cell RNA - HUVEC TERT2 [nTPM]":"17.1","Cell RNA - JURKAT [nTPM]":"19.4","Cell RNA - K-562 [nTPM]":"12.2","Cell RNA - Karpas-707 [nTPM]":"38.4","Cell RNA - LHCN-M2 [nTPM]":"17.3","Cell RNA - MCF7 [nTPM]":"47.5","Cell RNA - MOLT-4 [nTPM]":"23.5","Cell RNA - NB-4 [nTPM]":"39.9","Cell RNA - NTERA-2 [nTPM]":"16.1","Cell RNA - OE19 [nTPM]":"29.5","Cell RNA - PC-3 [nTPM]":"32.8","Cell RNA - REH [nTPM]":"21.7","Cell RNA - RH-30 [nTPM]":"23.2","Cell RNA - RPMI-8226 [nTPM]":"45.3","Cell RNA - RPTEC TERT1 [nTPM]":"18.5","Cell RNA - RT4 [nTPM]":"20.6","Cell RNA - SCLC-21H [nTPM]":"14.7","Cell RNA - SH-SY5Y [nTPM]":"12.9","Cell RNA - SiHa [nTPM]":"23.1","Cell RNA - SK-BR-3 [nTPM]":"35.5","Cell RNA - SK-MEL-30 [nTPM]":"33.1","Cell RNA - SuSa [nTPM]":"12.9","Cell RNA - T-47d [nTPM]":"8.7","Cell RNA - THP-1 [nTPM]":"32.9","Cell RNA - TIME [nTPM]":"13.1","Cell RNA - U-138 MG [nTPM]":"18.6","Cell RNA - U-2 OS [nTPM]":"6.6","Cell RNA - U-2197 [nTPM]":"26.7","Cell RNA - U-251 MG [nTPM]":"29.7","Cell RNA - U-266\/70 [nTPM]":"43.2","Cell RNA - U-266\/84 [nTPM]":"36.0","Cell RNA - U-698 [nTPM]":"27.9","Cell RNA - U-87 MG [nTPM]":"16.8","Cell RNA - U-937 [nTPM]":"44.1","Cell RNA - WM-115 [nTPM]":"12.3","Blood RNA - basophil [nTPM]":"96.4","Blood RNA - classical monocyte [nTPM]":"59.5","Blood RNA - eosinophil [nTPM]":"109.5","Blood RNA - gdT-cell [nTPM]":"73.9","Blood RNA - intermediate monocyte [nTPM]":"60.3","Blood RNA - MAIT T-cell [nTPM]":"74.4","Blood RNA - memory B-cell [nTPM]":"83.6","Blood RNA - memory CD4 T-cell [nTPM]":"78.3","Blood RNA - memory CD8 T-cell [nTPM]":"79.0","Blood RNA - myeloid DC [nTPM]":"63.4","Blood RNA - naive B-cell [nTPM]":"88.6","Blood RNA - naive CD4 T-cell [nTPM]":"81.3","Blood RNA - naive CD8 T-cell [nTPM]":"73.1","Blood RNA - neutrophil [nTPM]":"27.5","Blood RNA - NK-cell [nTPM]":"65.9","Blood RNA - non-classical monocyte [nTPM]":"72.6","Blood RNA - plasmacytoid DC [nTPM]":"53.3","Blood RNA - T-reg [nTPM]":"96.6","Blood RNA - total PBMC [nTPM]":"73.6","Brain RNA - amygdala [nTPM]":"11.5","Brain RNA - basal ganglia [nTPM]":"12.1","Brain RNA - cerebellum [nTPM]":"13.0","Brain RNA - cerebral cortex [nTPM]":"14.4","Brain RNA - hippocampal formation [nTPM]":"11.7","Brain RNA - hypothalamus [nTPM]":"13.9","Brain RNA - medulla oblongata [nTPM]":"12.7","Brain RNA - midbrain [nTPM]":"13.0","Brain RNA - pons [nTPM]":"13.1","Brain RNA - spinal cord [nTPM]":"11.9","Brain RNA - thalamus [nTPM]":"13.1","Brain RNA - white matter [nTPM]":"12.6","Single Cell Type RNA - Adipocytes [nTPM]":"14.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.8","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"42.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"24.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"26.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"30.7","Single Cell Type RNA - Bipolar cells [nTPM]":"11.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"21.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.5","Single Cell Type RNA - dendritic cells [nTPM]":"51.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"18.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.8","Single Cell Type RNA - Endothelial cells [nTPM]":"17.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"10.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"37.6","Single Cell Type RNA - Fibroblasts [nTPM]":"15.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.5","Single Cell Type RNA - granulocytes [nTPM]":"26.5","Single Cell Type RNA - Granulosa cells [nTPM]":"14.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.2","Single Cell Type RNA - Hepatocytes [nTPM]":"13.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.4","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.8","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"17.6","Single Cell Type RNA - Langerhans cells [nTPM]":"23.1","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"12.2","Single Cell Type RNA - Macrophages [nTPM]":"17.0","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"17.2","Single Cell Type RNA - Muller glia cells [nTPM]":"16.5","Single Cell Type RNA - NK-cells [nTPM]":"39.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.5","Single Cell Type RNA - Paneth cells [nTPM]":"17.8","Single Cell Type RNA - Peritubular cells [nTPM]":"9.8","Single Cell Type RNA - Plasma cells [nTPM]":"59.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"34.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"25.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.3","Single Cell Type RNA - Spermatocytes [nTPM]":"2.9","Single Cell Type RNA - Spermatogonia [nTPM]":"5.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"26.4","Single Cell Type RNA - T-cells [nTPM]":"50.2","Single Cell Type RNA - Theca cells [nTPM]":"15.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.5","Single Cell Type RNA - Urothelial cells [nTPM]":"14.3"},{"Gene":"RNF125","Gene synonym":["FLJ20456"],"Ensembl":"ENSG00000101695","Gene description":"Ring finger protein 125","Uniprot":["Q96EQ8"],"Chromosome":"18","Position":"32018825-32073219","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Adaptive immunity","Immunity","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"18.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"169.6","Early spermatids":"90.7","NK-cells":"160.6","Oligodendrocytes":"64.3","T-cells":"114.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"8.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"51.5","SK-MEL-30":"13.2","U-937":"11.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041514"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA041514":"AB_10795596"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.06e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-3"},"Tissue RNA - adipose tissue [nTPM]":"10.2","Tissue RNA - adrenal gland [nTPM]":"1.3","Tissue RNA - amygdala [nTPM]":"2.0","Tissue RNA - appendix [nTPM]":"5.2","Tissue RNA - basal ganglia [nTPM]":"3.7","Tissue RNA - bone marrow [nTPM]":"18.4","Tissue RNA - breast [nTPM]":"6.3","Tissue RNA - cerebellum [nTPM]":"2.7","Tissue RNA - cerebral cortex [nTPM]":"2.7","Tissue RNA - cervix [nTPM]":"3.9","Tissue RNA - choroid plexus [nTPM]":"1.6","Tissue RNA - colon [nTPM]":"5.0","Tissue RNA - duodenum [nTPM]":"10.5","Tissue RNA - endometrium 1 [nTPM]":"2.9","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"2.5","Tissue RNA - fallopian tube [nTPM]":"3.4","Tissue RNA - gallbladder [nTPM]":"3.3","Tissue RNA - heart muscle [nTPM]":"2.6","Tissue RNA - hippocampal formation [nTPM]":"1.9","Tissue RNA - hypothalamus [nTPM]":"2.3","Tissue RNA - kidney [nTPM]":"1.0","Tissue RNA - liver [nTPM]":"12.5","Tissue RNA - lung [nTPM]":"4.7","Tissue RNA - lymph node [nTPM]":"7.0","Tissue RNA - medulla oblongata [nTPM]":"3.6","Tissue RNA - midbrain [nTPM]":"3.2","Tissue RNA - ovary [nTPM]":"1.4","Tissue RNA - pancreas [nTPM]":"3.1","Tissue RNA - parathyroid gland [nTPM]":"1.7","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"3.7","Tissue RNA - pons [nTPM]":"3.4","Tissue RNA - prostate [nTPM]":"1.8","Tissue RNA - rectum [nTPM]":"6.4","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"2.2","Tissue RNA - seminal vesicle [nTPM]":"1.4","Tissue RNA - skeletal muscle [nTPM]":"2.3","Tissue RNA - skin 1 [nTPM]":"4.9","Tissue RNA - small intestine [nTPM]":"11.3","Tissue RNA - smooth muscle [nTPM]":"3.3","Tissue RNA - spinal cord [nTPM]":"2.6","Tissue RNA - spleen [nTPM]":"5.9","Tissue RNA - stomach 1 [nTPM]":"3.4","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"3.8","Tissue RNA - thymus [nTPM]":"5.3","Tissue RNA - thyroid gland [nTPM]":"1.4","Tissue RNA - tongue [nTPM]":"2.9","Tissue RNA - tonsil [nTPM]":"4.0","Tissue RNA - urinary bladder [nTPM]":"3.0","Tissue RNA - vagina [nTPM]":"1.7","Tissue RNA - white matter [nTPM]":"6.2","Cell RNA - A-431 [nTPM]":"1.2","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"0.5","Cell RNA - ASC TERT1 [nTPM]":"0.8","Cell RNA - BEWO [nTPM]":"1.0","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"2.5","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"1.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"0.9","Cell RNA - HAP1 [nTPM]":"1.6","Cell RNA - HBEC3-KT [nTPM]":"1.2","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"6.6","Cell RNA - HEK 293 [nTPM]":"2.6","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"8.9","Cell RNA - HMC-1 [nTPM]":"51.5","Cell RNA - HSkMC [nTPM]":"1.6","Cell RNA - hTCEpi [nTPM]":"2.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"2.8","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.4","Cell RNA - JURKAT [nTPM]":"2.7","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"1.9","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"2.0","Cell RNA - MOLT-4 [nTPM]":"2.3","Cell RNA - NB-4 [nTPM]":"8.2","Cell RNA - NTERA-2 [nTPM]":"4.2","Cell RNA - OE19 [nTPM]":"8.9","Cell RNA - PC-3 [nTPM]":"1.5","Cell RNA - REH [nTPM]":"9.2","Cell RNA - RH-30 [nTPM]":"0.6","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.5","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.9","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"13.2","Cell RNA - SuSa [nTPM]":"1.6","Cell RNA - T-47d [nTPM]":"1.3","Cell RNA - THP-1 [nTPM]":"4.2","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"5.9","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.6","Cell RNA - U-937 [nTPM]":"11.5","Cell RNA - WM-115 [nTPM]":"6.9","Blood RNA - basophil [nTPM]":"13.3","Blood RNA - classical monocyte [nTPM]":"4.5","Blood RNA - eosinophil [nTPM]":"4.5","Blood RNA - gdT-cell [nTPM]":"15.0","Blood RNA - intermediate monocyte [nTPM]":"2.5","Blood RNA - MAIT T-cell [nTPM]":"9.9","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"12.0","Blood RNA - memory CD8 T-cell [nTPM]":"12.8","Blood RNA - myeloid DC [nTPM]":"4.2","Blood RNA - naive B-cell [nTPM]":"2.3","Blood RNA - naive CD4 T-cell [nTPM]":"9.5","Blood RNA - naive CD8 T-cell [nTPM]":"12.3","Blood RNA - neutrophil [nTPM]":"1.9","Blood RNA - NK-cell [nTPM]":"15.5","Blood RNA - non-classical monocyte [nTPM]":"2.8","Blood RNA - plasmacytoid DC [nTPM]":"4.3","Blood RNA - T-reg [nTPM]":"13.7","Blood RNA - total PBMC [nTPM]":"6.9","Brain RNA - amygdala [nTPM]":"2.0","Brain RNA - basal ganglia [nTPM]":"3.7","Brain RNA - cerebellum [nTPM]":"2.7","Brain RNA - cerebral cortex [nTPM]":"2.7","Brain RNA - hippocampal formation [nTPM]":"1.9","Brain RNA - hypothalamus [nTPM]":"2.3","Brain RNA - medulla oblongata [nTPM]":"3.6","Brain RNA - midbrain [nTPM]":"3.2","Brain RNA - pons [nTPM]":"3.4","Brain RNA - spinal cord [nTPM]":"2.6","Brain RNA - thalamus [nTPM]":"3.8","Brain RNA - white matter [nTPM]":"6.2","Single Cell Type RNA - Adipocytes [nTPM]":"62.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.8","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"16.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"3.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"169.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.0","Single Cell Type RNA - Early spermatids [nTPM]":"90.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.1","Single Cell Type RNA - Endothelial cells [nTPM]":"28.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"15.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"5.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.4","Single Cell Type RNA - granulocytes [nTPM]":"18.9","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.5","Single Cell Type RNA - Hepatocytes [nTPM]":"25.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"19.2","Single Cell Type RNA - Langerhans cells [nTPM]":"12.6","Single Cell Type RNA - Late spermatids [nTPM]":"17.4","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"18.4","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"30.9","Single Cell Type RNA - monocytes [nTPM]":"23.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.7","Single Cell Type RNA - NK-cells [nTPM]":"160.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"64.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.1","Single Cell Type RNA - Paneth cells [nTPM]":"4.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"49.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"41.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"114.8","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.7","Single Cell Type RNA - Urothelial cells [nTPM]":"2.4"},{"Gene":"RNF13","Gene synonym":["RZF"],"Ensembl":"ENSG00000082996","Gene description":"Ring finger protein 13","Uniprot":["O43567"],"Chromosome":"3","Position":"149812770-149962139","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"591.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"462.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064784"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA064784":"AB_2685350"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.00e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Tissue RNA - adipose tissue [nTPM]":"48.2","Tissue RNA - adrenal gland [nTPM]":"41.2","Tissue RNA - amygdala [nTPM]":"58.1","Tissue RNA - appendix [nTPM]":"40.4","Tissue RNA - basal ganglia [nTPM]":"95.2","Tissue RNA - bone marrow [nTPM]":"19.9","Tissue RNA - breast [nTPM]":"53.9","Tissue RNA - cerebellum [nTPM]":"88.1","Tissue RNA - cerebral cortex [nTPM]":"91.5","Tissue RNA - cervix [nTPM]":"33.6","Tissue RNA - choroid plexus [nTPM]":"63.7","Tissue RNA - colon [nTPM]":"35.0","Tissue RNA - duodenum [nTPM]":"28.9","Tissue RNA - endometrium 1 [nTPM]":"33.3","Tissue RNA - epididymis [nTPM]":"57.2","Tissue RNA - esophagus [nTPM]":"32.6","Tissue RNA - fallopian tube [nTPM]":"30.2","Tissue RNA - gallbladder [nTPM]":"40.6","Tissue RNA - heart muscle [nTPM]":"34.4","Tissue RNA - hippocampal formation [nTPM]":"55.0","Tissue RNA - hypothalamus [nTPM]":"77.3","Tissue RNA - kidney [nTPM]":"67.9","Tissue RNA - liver [nTPM]":"73.8","Tissue RNA - lung [nTPM]":"64.1","Tissue RNA - lymph node [nTPM]":"38.0","Tissue RNA - medulla oblongata [nTPM]":"101.8","Tissue RNA - midbrain [nTPM]":"83.9","Tissue RNA - ovary [nTPM]":"35.6","Tissue RNA - pancreas [nTPM]":"36.1","Tissue RNA - parathyroid gland [nTPM]":"52.3","Tissue RNA - pituitary gland [nTPM]":"18.3","Tissue RNA - placenta [nTPM]":"64.1","Tissue RNA - pons [nTPM]":"100.8","Tissue RNA - prostate [nTPM]":"46.6","Tissue RNA - rectum [nTPM]":"37.1","Tissue RNA - retina [nTPM]":"40.4","Tissue RNA - salivary gland [nTPM]":"75.5","Tissue RNA - seminal vesicle [nTPM]":"39.3","Tissue RNA - skeletal muscle [nTPM]":"36.5","Tissue RNA - skin 1 [nTPM]":"32.5","Tissue RNA - small intestine [nTPM]":"30.5","Tissue RNA - smooth muscle [nTPM]":"36.9","Tissue RNA - spinal cord [nTPM]":"85.6","Tissue RNA - spleen [nTPM]":"53.0","Tissue RNA - stomach 1 [nTPM]":"34.3","Tissue RNA - testis [nTPM]":"25.2","Tissue RNA - thalamus [nTPM]":"75.9","Tissue RNA - thymus [nTPM]":"32.0","Tissue RNA - thyroid gland [nTPM]":"64.0","Tissue RNA - tongue [nTPM]":"42.6","Tissue RNA - tonsil [nTPM]":"33.2","Tissue RNA - urinary bladder [nTPM]":"42.3","Tissue RNA - vagina [nTPM]":"28.9","Tissue RNA - white matter [nTPM]":"131.0","Cell RNA - A-431 [nTPM]":"60.6","Cell RNA - A549 [nTPM]":"39.4","Cell RNA - AF22 [nTPM]":"24.4","Cell RNA - AN3-CA [nTPM]":"29.0","Cell RNA - ASC diff [nTPM]":"92.2","Cell RNA - ASC TERT1 [nTPM]":"55.2","Cell RNA - BEWO [nTPM]":"40.3","Cell RNA - BJ [nTPM]":"32.2","Cell RNA - BJ hTERT+ [nTPM]":"86.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"32.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"47.4","Cell RNA - CACO-2 [nTPM]":"33.4","Cell RNA - CAPAN-2 [nTPM]":"84.4","Cell RNA - Daudi [nTPM]":"26.6","Cell RNA - EFO-21 [nTPM]":"48.7","Cell RNA - fHDF\/TERT166 [nTPM]":"42.0","Cell RNA - GAMG [nTPM]":"58.7","Cell RNA - HaCaT [nTPM]":"58.0","Cell RNA - HAP1 [nTPM]":"37.5","Cell RNA - HBEC3-KT [nTPM]":"41.5","Cell RNA - HBF TERT88 [nTPM]":"42.9","Cell RNA - HDLM-2 [nTPM]":"34.1","Cell RNA - HEK 293 [nTPM]":"24.6","Cell RNA - HEL [nTPM]":"35.8","Cell RNA - HeLa [nTPM]":"17.3","Cell RNA - Hep G2 [nTPM]":"31.2","Cell RNA - HHSteC [nTPM]":"61.5","Cell RNA - HL-60 [nTPM]":"35.0","Cell RNA - HMC-1 [nTPM]":"41.8","Cell RNA - HSkMC [nTPM]":"59.9","Cell RNA - hTCEpi [nTPM]":"73.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.5","Cell RNA - hTERT-HME1 [nTPM]":"71.8","Cell RNA - hTERT-RPE1 [nTPM]":"37.3","Cell RNA - HUVEC TERT2 [nTPM]":"37.0","Cell RNA - JURKAT [nTPM]":"24.9","Cell RNA - K-562 [nTPM]":"10.1","Cell RNA - Karpas-707 [nTPM]":"49.7","Cell RNA - LHCN-M2 [nTPM]":"28.0","Cell RNA - MCF7 [nTPM]":"34.5","Cell RNA - MOLT-4 [nTPM]":"26.2","Cell RNA - NB-4 [nTPM]":"18.8","Cell RNA - NTERA-2 [nTPM]":"16.8","Cell RNA - OE19 [nTPM]":"58.6","Cell RNA - PC-3 [nTPM]":"29.1","Cell RNA - REH [nTPM]":"19.0","Cell RNA - RH-30 [nTPM]":"26.7","Cell RNA - RPMI-8226 [nTPM]":"108.5","Cell RNA - RPTEC TERT1 [nTPM]":"54.2","Cell RNA - RT4 [nTPM]":"29.6","Cell RNA - SCLC-21H [nTPM]":"12.6","Cell RNA - SH-SY5Y [nTPM]":"37.6","Cell RNA - SiHa [nTPM]":"28.5","Cell RNA - SK-BR-3 [nTPM]":"39.9","Cell RNA - SK-MEL-30 [nTPM]":"110.3","Cell RNA - SuSa [nTPM]":"19.2","Cell RNA - T-47d [nTPM]":"79.2","Cell RNA - THP-1 [nTPM]":"34.0","Cell RNA - TIME [nTPM]":"37.8","Cell RNA - U-138 MG [nTPM]":"40.8","Cell RNA - U-2 OS [nTPM]":"16.5","Cell RNA - U-2197 [nTPM]":"45.6","Cell RNA - U-251 MG [nTPM]":"23.4","Cell RNA - U-266\/70 [nTPM]":"89.9","Cell RNA - U-266\/84 [nTPM]":"61.9","Cell RNA - U-698 [nTPM]":"51.5","Cell RNA - U-87 MG [nTPM]":"35.9","Cell RNA - U-937 [nTPM]":"30.1","Cell RNA - WM-115 [nTPM]":"23.6","Blood RNA - basophil [nTPM]":"98.2","Blood RNA - classical monocyte [nTPM]":"130.1","Blood RNA - eosinophil [nTPM]":"106.5","Blood RNA - gdT-cell [nTPM]":"37.4","Blood RNA - intermediate monocyte [nTPM]":"153.8","Blood RNA - MAIT T-cell [nTPM]":"48.8","Blood RNA - memory B-cell [nTPM]":"51.9","Blood RNA - memory CD4 T-cell [nTPM]":"41.5","Blood RNA - memory CD8 T-cell [nTPM]":"44.8","Blood RNA - myeloid DC [nTPM]":"93.1","Blood RNA - naive B-cell [nTPM]":"48.4","Blood RNA - naive CD4 T-cell [nTPM]":"38.0","Blood RNA - naive CD8 T-cell [nTPM]":"42.4","Blood RNA - neutrophil [nTPM]":"462.3","Blood RNA - NK-cell [nTPM]":"46.3","Blood RNA - non-classical monocyte [nTPM]":"207.8","Blood RNA - plasmacytoid DC [nTPM]":"68.3","Blood RNA - T-reg [nTPM]":"48.7","Blood RNA - total PBMC [nTPM]":"104.5","Brain RNA - amygdala [nTPM]":"58.1","Brain RNA - basal ganglia [nTPM]":"95.2","Brain RNA - cerebellum [nTPM]":"88.1","Brain RNA - cerebral cortex [nTPM]":"91.5","Brain RNA - hippocampal formation [nTPM]":"55.0","Brain RNA - hypothalamus [nTPM]":"77.3","Brain RNA - medulla oblongata [nTPM]":"101.8","Brain RNA - midbrain [nTPM]":"83.9","Brain RNA - pons [nTPM]":"100.8","Brain RNA - spinal cord [nTPM]":"85.6","Brain RNA - thalamus [nTPM]":"75.9","Brain RNA - white matter [nTPM]":"131.0","Single Cell Type RNA - Adipocytes [nTPM]":"100.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"109.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"72.3","Single Cell Type RNA - Astrocytes [nTPM]":"78.7","Single Cell Type RNA - B-cells [nTPM]":"55.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"73.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"68.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"84.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"74.0","Single Cell Type RNA - Bipolar cells [nTPM]":"44.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"54.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"51.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"27.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"48.6","Single Cell Type RNA - Club cells [nTPM]":"68.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"47.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"101.2","Single Cell Type RNA - dendritic cells [nTPM]":"61.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"30.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"43.0","Single Cell Type RNA - Ductal cells [nTPM]":"63.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"32.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"34.5","Single Cell Type RNA - Endothelial cells [nTPM]":"69.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.3","Single Cell Type RNA - Erythroid cells [nTPM]":"32.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"122.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"70.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"83.5","Single Cell Type RNA - Fibroblasts [nTPM]":"84.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"31.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"39.7","Single Cell Type RNA - granulocytes [nTPM]":"60.8","Single Cell Type RNA - Granulosa cells [nTPM]":"14.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"80.3","Single Cell Type RNA - Hepatocytes [nTPM]":"53.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"201.2","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"98.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"27.7","Single Cell Type RNA - Ionocytes [nTPM]":"67.1","Single Cell Type RNA - Kupffer cells [nTPM]":"183.9","Single Cell Type RNA - Langerhans cells [nTPM]":"173.7","Single Cell Type RNA - Late spermatids [nTPM]":"6.7","Single Cell Type RNA - Leydig cells [nTPM]":"76.1","Single Cell Type RNA - Macrophages [nTPM]":"177.6","Single Cell Type RNA - Melanocytes [nTPM]":"103.2","Single Cell Type RNA - Microglial cells [nTPM]":"92.8","Single Cell Type RNA - monocytes [nTPM]":"93.5","Single Cell Type RNA - Muller glia cells [nTPM]":"98.5","Single Cell Type RNA - NK-cells [nTPM]":"38.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"115.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"591.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"58.7","Single Cell Type RNA - Paneth cells [nTPM]":"33.6","Single Cell Type RNA - Peritubular cells [nTPM]":"88.0","Single Cell Type RNA - Plasma cells [nTPM]":"62.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"71.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"38.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"71.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"40.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"37.2","Single Cell Type RNA - Sertoli cells [nTPM]":"92.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"76.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"55.5","Single Cell Type RNA - Spermatocytes [nTPM]":"23.6","Single Cell Type RNA - Spermatogonia [nTPM]":"32.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"52.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"72.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"52.5","Single Cell Type RNA - T-cells [nTPM]":"49.8","Single Cell Type RNA - Theca cells [nTPM]":"38.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"27.7","Single Cell Type RNA - Urothelial cells [nTPM]":"55.8"},{"Gene":"RNF139","Gene synonym":["HRCA1","RCA1","TRC8"],"Ensembl":"ENSG00000170881","Gene description":"Ring finger protein 139","Uniprot":["Q8WU17"],"Chromosome":"8","Position":"124474880-124488618","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Receptor","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"93.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Early spermatids":"810.1","Late spermatids":"992.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001202"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA001202":"AB_1079824"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.54e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Tissue RNA - adipose tissue [nTPM]":"23.5","Tissue RNA - adrenal gland [nTPM]":"20.8","Tissue RNA - amygdala [nTPM]":"10.0","Tissue RNA - appendix [nTPM]":"15.9","Tissue RNA - basal ganglia [nTPM]":"11.1","Tissue RNA - bone marrow [nTPM]":"93.2","Tissue RNA - breast [nTPM]":"18.9","Tissue RNA - cerebellum [nTPM]":"14.8","Tissue RNA - cerebral cortex [nTPM]":"12.7","Tissue RNA - cervix [nTPM]":"16.6","Tissue RNA - choroid plexus [nTPM]":"11.2","Tissue RNA - colon [nTPM]":"15.6","Tissue RNA - duodenum [nTPM]":"9.2","Tissue RNA - endometrium 1 [nTPM]":"20.2","Tissue RNA - epididymis [nTPM]":"13.6","Tissue RNA - esophagus [nTPM]":"16.5","Tissue RNA - fallopian tube [nTPM]":"16.7","Tissue RNA - gallbladder [nTPM]":"16.8","Tissue RNA - heart muscle [nTPM]":"15.3","Tissue RNA - hippocampal formation [nTPM]":"11.0","Tissue RNA - hypothalamus [nTPM]":"11.0","Tissue RNA - kidney [nTPM]":"15.3","Tissue RNA - liver [nTPM]":"26.1","Tissue RNA - lung [nTPM]":"16.6","Tissue RNA - lymph node [nTPM]":"17.3","Tissue RNA - medulla oblongata [nTPM]":"11.0","Tissue RNA - midbrain [nTPM]":"10.8","Tissue RNA - ovary [nTPM]":"23.6","Tissue RNA - pancreas [nTPM]":"14.4","Tissue RNA - parathyroid gland [nTPM]":"11.8","Tissue RNA - pituitary gland [nTPM]":"10.2","Tissue RNA - placenta [nTPM]":"19.4","Tissue RNA - pons [nTPM]":"11.0","Tissue RNA - prostate [nTPM]":"14.9","Tissue RNA - rectum [nTPM]":"14.8","Tissue RNA - retina [nTPM]":"12.4","Tissue RNA - salivary gland [nTPM]":"16.5","Tissue RNA - seminal vesicle [nTPM]":"13.3","Tissue RNA - skeletal muscle [nTPM]":"20.3","Tissue RNA - skin 1 [nTPM]":"17.2","Tissue RNA - small intestine [nTPM]":"14.2","Tissue RNA - smooth muscle [nTPM]":"20.3","Tissue RNA - spinal cord [nTPM]":"11.8","Tissue RNA - spleen [nTPM]":"13.9","Tissue RNA - stomach 1 [nTPM]":"13.9","Tissue RNA - testis [nTPM]":"68.7","Tissue RNA - thalamus [nTPM]":"11.7","Tissue RNA - thymus [nTPM]":"19.3","Tissue RNA - thyroid gland [nTPM]":"16.3","Tissue RNA - tongue [nTPM]":"22.6","Tissue RNA - tonsil [nTPM]":"14.8","Tissue RNA - urinary bladder [nTPM]":"16.7","Tissue RNA - vagina [nTPM]":"12.4","Tissue RNA - white matter [nTPM]":"15.0","Cell RNA - A-431 [nTPM]":"26.6","Cell RNA - A549 [nTPM]":"17.1","Cell RNA - AF22 [nTPM]":"21.6","Cell RNA - AN3-CA [nTPM]":"20.3","Cell RNA - ASC diff [nTPM]":"43.2","Cell RNA - ASC TERT1 [nTPM]":"34.1","Cell RNA - BEWO [nTPM]":"16.6","Cell RNA - BJ [nTPM]":"23.5","Cell RNA - BJ hTERT+ [nTPM]":"44.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.7","Cell RNA - CACO-2 [nTPM]":"10.9","Cell RNA - CAPAN-2 [nTPM]":"21.6","Cell RNA - Daudi [nTPM]":"27.5","Cell RNA - EFO-21 [nTPM]":"27.8","Cell RNA - fHDF\/TERT166 [nTPM]":"31.7","Cell RNA - GAMG [nTPM]":"14.3","Cell RNA - HaCaT [nTPM]":"19.7","Cell RNA - HAP1 [nTPM]":"18.3","Cell RNA - HBEC3-KT [nTPM]":"28.4","Cell RNA - HBF TERT88 [nTPM]":"28.9","Cell RNA - HDLM-2 [nTPM]":"37.6","Cell RNA - HEK 293 [nTPM]":"24.5","Cell RNA - HEL [nTPM]":"41.1","Cell RNA - HeLa [nTPM]":"11.9","Cell RNA - Hep G2 [nTPM]":"22.9","Cell RNA - HHSteC [nTPM]":"33.3","Cell RNA - HL-60 [nTPM]":"19.6","Cell RNA - HMC-1 [nTPM]":"23.2","Cell RNA - HSkMC [nTPM]":"30.5","Cell RNA - hTCEpi [nTPM]":"41.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.5","Cell RNA - hTERT-HME1 [nTPM]":"55.9","Cell RNA - hTERT-RPE1 [nTPM]":"27.1","Cell RNA - HUVEC TERT2 [nTPM]":"26.2","Cell RNA - JURKAT [nTPM]":"26.8","Cell RNA - K-562 [nTPM]":"29.1","Cell RNA - Karpas-707 [nTPM]":"41.3","Cell RNA - LHCN-M2 [nTPM]":"22.2","Cell RNA - MCF7 [nTPM]":"70.2","Cell RNA - MOLT-4 [nTPM]":"32.9","Cell RNA - NB-4 [nTPM]":"13.6","Cell RNA - NTERA-2 [nTPM]":"14.3","Cell RNA - OE19 [nTPM]":"52.6","Cell RNA - PC-3 [nTPM]":"25.6","Cell RNA - REH [nTPM]":"13.2","Cell RNA - RH-30 [nTPM]":"14.9","Cell RNA - RPMI-8226 [nTPM]":"27.0","Cell RNA - RPTEC TERT1 [nTPM]":"35.3","Cell RNA - RT4 [nTPM]":"34.4","Cell RNA - SCLC-21H [nTPM]":"9.4","Cell RNA - SH-SY5Y [nTPM]":"22.3","Cell RNA - SiHa [nTPM]":"31.0","Cell RNA - SK-BR-3 [nTPM]":"76.5","Cell RNA - SK-MEL-30 [nTPM]":"33.4","Cell RNA - SuSa [nTPM]":"16.5","Cell RNA - T-47d [nTPM]":"35.7","Cell RNA - THP-1 [nTPM]":"20.7","Cell RNA - TIME [nTPM]":"20.6","Cell RNA - U-138 MG [nTPM]":"13.9","Cell RNA - U-2 OS [nTPM]":"29.7","Cell RNA - U-2197 [nTPM]":"22.2","Cell RNA - U-251 MG [nTPM]":"26.3","Cell RNA - U-266\/70 [nTPM]":"32.9","Cell RNA - U-266\/84 [nTPM]":"40.9","Cell RNA - U-698 [nTPM]":"28.6","Cell RNA - U-87 MG [nTPM]":"19.9","Cell RNA - U-937 [nTPM]":"31.7","Cell RNA - WM-115 [nTPM]":"13.9","Blood RNA - basophil [nTPM]":"2.7","Blood RNA - classical monocyte [nTPM]":"6.2","Blood RNA - eosinophil [nTPM]":"10.1","Blood RNA - gdT-cell [nTPM]":"8.7","Blood RNA - intermediate monocyte [nTPM]":"4.1","Blood RNA - MAIT T-cell [nTPM]":"11.0","Blood RNA - memory B-cell [nTPM]":"7.9","Blood RNA - memory CD4 T-cell [nTPM]":"7.8","Blood RNA - memory CD8 T-cell [nTPM]":"10.5","Blood RNA - myeloid DC [nTPM]":"8.4","Blood RNA - naive B-cell [nTPM]":"7.1","Blood RNA - naive CD4 T-cell [nTPM]":"8.1","Blood RNA - naive CD8 T-cell [nTPM]":"8.4","Blood RNA - neutrophil [nTPM]":"8.5","Blood RNA - NK-cell [nTPM]":"7.2","Blood RNA - non-classical monocyte [nTPM]":"11.4","Blood RNA - plasmacytoid DC [nTPM]":"4.0","Blood RNA - T-reg [nTPM]":"11.4","Blood RNA - total PBMC [nTPM]":"6.7","Brain RNA - amygdala [nTPM]":"10.0","Brain RNA - basal ganglia [nTPM]":"11.1","Brain RNA - cerebellum [nTPM]":"14.8","Brain RNA - cerebral cortex [nTPM]":"12.7","Brain RNA - hippocampal formation [nTPM]":"11.0","Brain RNA - hypothalamus [nTPM]":"11.0","Brain RNA - medulla oblongata [nTPM]":"11.0","Brain RNA - midbrain [nTPM]":"10.8","Brain RNA - pons [nTPM]":"11.0","Brain RNA - spinal cord [nTPM]":"11.8","Brain RNA - thalamus [nTPM]":"11.7","Brain RNA - white matter [nTPM]":"15.0","Single Cell Type RNA - Adipocytes [nTPM]":"21.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.4","Single Cell Type RNA - Astrocytes [nTPM]":"11.8","Single Cell Type RNA - B-cells [nTPM]":"66.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"66.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"62.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"27.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"58.6","Single Cell Type RNA - Bipolar cells [nTPM]":"14.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"31.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"19.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"34.3","Single Cell Type RNA - Club cells [nTPM]":"18.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"42.3","Single Cell Type RNA - dendritic cells [nTPM]":"58.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"22.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"19.9","Single Cell Type RNA - Early spermatids [nTPM]":"810.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"31.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.6","Single Cell Type RNA - Endothelial cells [nTPM]":"24.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.7","Single Cell Type RNA - Erythroid cells [nTPM]":"27.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"55.9","Single Cell Type RNA - Fibroblasts [nTPM]":"40.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"37.1","Single Cell Type RNA - granulocytes [nTPM]":"20.3","Single Cell Type RNA - Granulosa cells [nTPM]":"23.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.9","Single Cell Type RNA - Hepatocytes [nTPM]":"31.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.0","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.5","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"33.7","Single Cell Type RNA - Langerhans cells [nTPM]":"74.4","Single Cell Type RNA - Late spermatids [nTPM]":"992.2","Single Cell Type RNA - Leydig cells [nTPM]":"29.5","Single Cell Type RNA - Macrophages [nTPM]":"43.4","Single Cell Type RNA - Melanocytes [nTPM]":"35.6","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"26.5","Single Cell Type RNA - Muller glia cells [nTPM]":"21.3","Single Cell Type RNA - NK-cells [nTPM]":"26.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.5","Single Cell Type RNA - Paneth cells [nTPM]":"11.4","Single Cell Type RNA - Peritubular cells [nTPM]":"27.1","Single Cell Type RNA - Plasma cells [nTPM]":"35.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"41.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"22.7","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"39.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"49.2","Single Cell Type RNA - Spermatocytes [nTPM]":"62.3","Single Cell Type RNA - Spermatogonia [nTPM]":"24.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"46.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"70.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"75.5","Single Cell Type RNA - T-cells [nTPM]":"83.5","Single Cell Type RNA - Theca cells [nTPM]":"22.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.2","Single Cell Type RNA - Urothelial cells [nTPM]":"55.5"},{"Gene":"RNF146","Gene synonym":["dactylidin","dJ351K20.1","DKFZp434O1427"],"Ensembl":"ENSG00000118518","Gene description":"Ring finger protein 146","Uniprot":["Q9NTX7"],"Chromosome":"6","Position":"127266682-127288567","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway","Wnt signaling pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027158","HPA027209"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA027158":"AB_10600772","HPA027209":"AB_10602312"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.26e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.32e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Tissue RNA - adipose tissue [nTPM]":"52.9","Tissue RNA - adrenal gland [nTPM]":"37.0","Tissue RNA - amygdala [nTPM]":"49.5","Tissue RNA - appendix [nTPM]":"32.4","Tissue RNA - basal ganglia [nTPM]":"56.0","Tissue RNA - bone marrow [nTPM]":"10.6","Tissue RNA - breast [nTPM]":"42.7","Tissue RNA - cerebellum [nTPM]":"79.4","Tissue RNA - cerebral cortex [nTPM]":"61.2","Tissue RNA - cervix [nTPM]":"48.1","Tissue RNA - choroid plexus [nTPM]":"36.2","Tissue RNA - colon [nTPM]":"40.5","Tissue RNA - duodenum [nTPM]":"21.9","Tissue RNA - endometrium 1 [nTPM]":"57.4","Tissue RNA - epididymis [nTPM]":"60.8","Tissue RNA - esophagus [nTPM]":"25.3","Tissue RNA - fallopian tube [nTPM]":"42.4","Tissue RNA - gallbladder [nTPM]":"38.6","Tissue RNA - heart muscle [nTPM]":"46.9","Tissue RNA - hippocampal formation [nTPM]":"50.7","Tissue RNA - hypothalamus [nTPM]":"51.6","Tissue RNA - kidney [nTPM]":"37.1","Tissue RNA - liver [nTPM]":"31.8","Tissue RNA - lung [nTPM]":"38.7","Tissue RNA - lymph node [nTPM]":"35.1","Tissue RNA - medulla oblongata [nTPM]":"53.2","Tissue RNA - midbrain [nTPM]":"52.1","Tissue RNA - ovary [nTPM]":"49.5","Tissue RNA - pancreas [nTPM]":"23.3","Tissue RNA - parathyroid gland [nTPM]":"40.0","Tissue RNA - pituitary gland [nTPM]":"33.3","Tissue RNA - placenta [nTPM]":"51.8","Tissue RNA - pons [nTPM]":"56.8","Tissue RNA - prostate [nTPM]":"31.7","Tissue RNA - rectum [nTPM]":"30.9","Tissue RNA - retina [nTPM]":"48.1","Tissue RNA - salivary gland [nTPM]":"31.2","Tissue RNA - seminal vesicle [nTPM]":"34.5","Tissue RNA - skeletal muscle [nTPM]":"114.9","Tissue RNA - skin 1 [nTPM]":"29.5","Tissue RNA - small intestine [nTPM]":"31.1","Tissue RNA - smooth muscle [nTPM]":"45.9","Tissue RNA - spinal cord [nTPM]":"55.2","Tissue RNA - spleen [nTPM]":"47.1","Tissue RNA - stomach 1 [nTPM]":"29.9","Tissue RNA - testis [nTPM]":"31.3","Tissue RNA - thalamus [nTPM]":"52.5","Tissue RNA - thymus [nTPM]":"24.3","Tissue RNA - thyroid gland [nTPM]":"47.1","Tissue RNA - tongue [nTPM]":"91.5","Tissue RNA - tonsil [nTPM]":"33.3","Tissue RNA - urinary bladder [nTPM]":"36.9","Tissue RNA - vagina [nTPM]":"34.3","Tissue RNA - white matter [nTPM]":"61.5","Cell RNA - A-431 [nTPM]":"13.2","Cell RNA - A549 [nTPM]":"16.2","Cell RNA - AF22 [nTPM]":"60.3","Cell RNA - AN3-CA [nTPM]":"53.6","Cell RNA - ASC diff [nTPM]":"54.7","Cell RNA - ASC TERT1 [nTPM]":"54.3","Cell RNA - BEWO [nTPM]":"22.2","Cell RNA - BJ [nTPM]":"43.5","Cell RNA - BJ hTERT+ [nTPM]":"69.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"22.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"32.4","Cell RNA - CACO-2 [nTPM]":"21.3","Cell RNA - CAPAN-2 [nTPM]":"19.3","Cell RNA - Daudi [nTPM]":"23.6","Cell RNA - EFO-21 [nTPM]":"30.3","Cell RNA - fHDF\/TERT166 [nTPM]":"35.7","Cell RNA - GAMG [nTPM]":"36.2","Cell RNA - HaCaT [nTPM]":"16.4","Cell RNA - HAP1 [nTPM]":"18.1","Cell RNA - HBEC3-KT [nTPM]":"20.4","Cell RNA - HBF TERT88 [nTPM]":"32.9","Cell RNA - HDLM-2 [nTPM]":"27.6","Cell RNA - HEK 293 [nTPM]":"16.0","Cell RNA - HEL [nTPM]":"30.3","Cell RNA - HeLa [nTPM]":"21.8","Cell RNA - Hep G2 [nTPM]":"30.0","Cell RNA - HHSteC [nTPM]":"54.0","Cell RNA - HL-60 [nTPM]":"18.0","Cell RNA - HMC-1 [nTPM]":"20.6","Cell RNA - HSkMC [nTPM]":"47.6","Cell RNA - hTCEpi [nTPM]":"42.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.1","Cell RNA - hTERT-HME1 [nTPM]":"51.1","Cell RNA - hTERT-RPE1 [nTPM]":"52.5","Cell RNA - HUVEC TERT2 [nTPM]":"40.6","Cell RNA - JURKAT [nTPM]":"23.2","Cell RNA - K-562 [nTPM]":"33.0","Cell RNA - Karpas-707 [nTPM]":"22.5","Cell RNA - LHCN-M2 [nTPM]":"50.7","Cell RNA - MCF7 [nTPM]":"25.2","Cell RNA - MOLT-4 [nTPM]":"17.9","Cell RNA - NB-4 [nTPM]":"32.0","Cell RNA - NTERA-2 [nTPM]":"22.1","Cell RNA - OE19 [nTPM]":"8.1","Cell RNA - PC-3 [nTPM]":"17.1","Cell RNA - REH [nTPM]":"22.6","Cell RNA - RH-30 [nTPM]":"15.7","Cell RNA - RPMI-8226 [nTPM]":"12.1","Cell RNA - RPTEC TERT1 [nTPM]":"32.4","Cell RNA - RT4 [nTPM]":"14.3","Cell RNA - SCLC-21H [nTPM]":"36.0","Cell RNA - SH-SY5Y [nTPM]":"36.6","Cell RNA - SiHa [nTPM]":"17.1","Cell RNA - SK-BR-3 [nTPM]":"23.6","Cell RNA - SK-MEL-30 [nTPM]":"27.7","Cell RNA - SuSa [nTPM]":"35.5","Cell RNA - T-47d [nTPM]":"16.1","Cell RNA - THP-1 [nTPM]":"60.8","Cell RNA - TIME [nTPM]":"48.3","Cell RNA - U-138 MG [nTPM]":"39.7","Cell RNA - U-2 OS [nTPM]":"13.1","Cell RNA - U-2197 [nTPM]":"41.8","Cell RNA - U-251 MG [nTPM]":"31.7","Cell RNA - U-266\/70 [nTPM]":"32.3","Cell RNA - U-266\/84 [nTPM]":"22.0","Cell RNA - U-698 [nTPM]":"15.6","Cell RNA - U-87 MG [nTPM]":"30.5","Cell RNA - U-937 [nTPM]":"31.0","Cell RNA - WM-115 [nTPM]":"38.5","Blood RNA - basophil [nTPM]":"27.5","Blood RNA - classical monocyte [nTPM]":"30.0","Blood RNA - eosinophil [nTPM]":"26.6","Blood RNA - gdT-cell [nTPM]":"14.3","Blood RNA - intermediate monocyte [nTPM]":"32.4","Blood RNA - MAIT T-cell [nTPM]":"14.7","Blood RNA - memory B-cell [nTPM]":"17.4","Blood RNA - memory CD4 T-cell [nTPM]":"12.2","Blood RNA - memory CD8 T-cell [nTPM]":"16.3","Blood RNA - myeloid DC [nTPM]":"22.8","Blood RNA - naive B-cell [nTPM]":"17.9","Blood RNA - naive CD4 T-cell [nTPM]":"11.0","Blood RNA - naive CD8 T-cell [nTPM]":"15.5","Blood RNA - neutrophil [nTPM]":"37.0","Blood RNA - NK-cell [nTPM]":"19.8","Blood RNA - non-classical monocyte [nTPM]":"40.1","Blood RNA - plasmacytoid DC [nTPM]":"11.7","Blood RNA - T-reg [nTPM]":"15.0","Blood RNA - total PBMC [nTPM]":"16.1","Brain RNA - amygdala [nTPM]":"49.5","Brain RNA - basal ganglia [nTPM]":"56.0","Brain RNA - cerebellum [nTPM]":"79.4","Brain RNA - cerebral cortex [nTPM]":"61.2","Brain RNA - hippocampal formation [nTPM]":"50.7","Brain RNA - hypothalamus [nTPM]":"51.6","Brain RNA - medulla oblongata [nTPM]":"53.2","Brain RNA - midbrain [nTPM]":"52.1","Brain RNA - pons [nTPM]":"56.8","Brain RNA - spinal cord [nTPM]":"55.2","Brain RNA - thalamus [nTPM]":"52.5","Brain RNA - white matter [nTPM]":"61.5","Single Cell Type RNA - Adipocytes [nTPM]":"24.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.3","Single Cell Type RNA - Astrocytes [nTPM]":"35.6","Single Cell Type RNA - B-cells [nTPM]":"23.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Bipolar cells [nTPM]":"34.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"38.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"31.5","Single Cell Type RNA - Club cells [nTPM]":"16.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"29.0","Single Cell Type RNA - dendritic cells [nTPM]":"14.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"41.1","Single Cell Type RNA - Ductal cells [nTPM]":"28.0","Single Cell Type RNA - Early spermatids [nTPM]":"52.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.5","Single Cell Type RNA - Endothelial cells [nTPM]":"30.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.4","Single Cell Type RNA - Erythroid cells [nTPM]":"12.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"53.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"27.2","Single Cell Type RNA - Fibroblasts [nTPM]":"50.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.5","Single Cell Type RNA - granulocytes [nTPM]":"22.2","Single Cell Type RNA - Granulosa cells [nTPM]":"28.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"31.4","Single Cell Type RNA - Hepatocytes [nTPM]":"30.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"26.3","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"54.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.1","Single Cell Type RNA - Ionocytes [nTPM]":"38.7","Single Cell Type RNA - Kupffer cells [nTPM]":"68.4","Single Cell Type RNA - Langerhans cells [nTPM]":"24.6","Single Cell Type RNA - Late spermatids [nTPM]":"45.4","Single Cell Type RNA - Leydig cells [nTPM]":"69.6","Single Cell Type RNA - Macrophages [nTPM]":"29.9","Single Cell Type RNA - Melanocytes [nTPM]":"46.2","Single Cell Type RNA - Microglial cells [nTPM]":"42.2","Single Cell Type RNA - monocytes [nTPM]":"31.1","Single Cell Type RNA - Muller glia cells [nTPM]":"41.1","Single Cell Type RNA - NK-cells [nTPM]":"28.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"56.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"76.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.0","Single Cell Type RNA - Paneth cells [nTPM]":"17.0","Single Cell Type RNA - Peritubular cells [nTPM]":"66.5","Single Cell Type RNA - Plasma cells [nTPM]":"9.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"26.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"51.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"36.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"31.9","Single Cell Type RNA - Spermatocytes [nTPM]":"41.7","Single Cell Type RNA - Spermatogonia [nTPM]":"24.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"38.4","Single Cell Type RNA - T-cells [nTPM]":"20.8","Single Cell Type RNA - Theca cells [nTPM]":"36.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.9","Single Cell Type RNA - Urothelial cells [nTPM]":"25.9"},{"Gene":"RNF168","Gene synonym":["FLJ35794"],"Ensembl":"ENSG00000163961","Gene description":"Ring finger protein 168","Uniprot":["Q8IYW5"],"Chromosome":"3","Position":"196468783-196503768","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Ubl conjugation pathway"],"Molecular function":["Chromatin regulator","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"199.9","Late spermatids":"459.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046109"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA046109":"AB_2679540"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.21e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.29e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.81e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.31e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.6","Tissue RNA - adrenal gland [nTPM]":"4.8","Tissue RNA - amygdala [nTPM]":"3.9","Tissue RNA - appendix [nTPM]":"6.0","Tissue RNA - basal ganglia [nTPM]":"4.2","Tissue RNA - bone marrow [nTPM]":"20.6","Tissue RNA - breast [nTPM]":"6.8","Tissue RNA - cerebellum [nTPM]":"5.9","Tissue RNA - cerebral cortex [nTPM]":"4.3","Tissue RNA - cervix [nTPM]":"9.3","Tissue RNA - choroid plexus [nTPM]":"4.4","Tissue RNA - colon [nTPM]":"6.1","Tissue RNA - duodenum [nTPM]":"6.1","Tissue RNA - endometrium 1 [nTPM]":"6.0","Tissue RNA - epididymis [nTPM]":"4.0","Tissue RNA - esophagus [nTPM]":"7.9","Tissue RNA - fallopian tube [nTPM]":"5.9","Tissue RNA - gallbladder [nTPM]":"4.5","Tissue RNA - heart muscle [nTPM]":"6.8","Tissue RNA - hippocampal formation [nTPM]":"3.2","Tissue RNA - hypothalamus [nTPM]":"6.3","Tissue RNA - kidney [nTPM]":"4.7","Tissue RNA - liver [nTPM]":"10.4","Tissue RNA - lung [nTPM]":"8.1","Tissue RNA - lymph node [nTPM]":"7.2","Tissue RNA - medulla oblongata [nTPM]":"6.1","Tissue RNA - midbrain [nTPM]":"5.2","Tissue RNA - ovary [nTPM]":"7.4","Tissue RNA - pancreas [nTPM]":"4.8","Tissue RNA - parathyroid gland [nTPM]":"4.0","Tissue RNA - pituitary gland [nTPM]":"3.5","Tissue RNA - placenta [nTPM]":"5.4","Tissue RNA - pons [nTPM]":"6.5","Tissue RNA - prostate [nTPM]":"5.3","Tissue RNA - rectum [nTPM]":"5.7","Tissue RNA - retina [nTPM]":"4.9","Tissue RNA - salivary gland [nTPM]":"5.8","Tissue RNA - seminal vesicle [nTPM]":"4.1","Tissue RNA - skeletal muscle [nTPM]":"13.1","Tissue RNA - skin 1 [nTPM]":"11.5","Tissue RNA - small intestine [nTPM]":"5.6","Tissue RNA - smooth muscle [nTPM]":"5.3","Tissue RNA - spinal cord [nTPM]":"4.9","Tissue RNA - spleen [nTPM]":"6.8","Tissue RNA - stomach 1 [nTPM]":"5.8","Tissue RNA - testis [nTPM]":"10.7","Tissue RNA - thalamus [nTPM]":"6.0","Tissue RNA - thymus [nTPM]":"7.7","Tissue RNA - thyroid gland [nTPM]":"4.9","Tissue RNA - tongue [nTPM]":"8.3","Tissue RNA - tonsil [nTPM]":"8.7","Tissue RNA - urinary bladder [nTPM]":"6.7","Tissue RNA - vagina [nTPM]":"9.3","Tissue RNA - white matter [nTPM]":"6.0","Cell RNA - A-431 [nTPM]":"21.6","Cell RNA - A549 [nTPM]":"8.5","Cell RNA - AF22 [nTPM]":"14.8","Cell RNA - AN3-CA [nTPM]":"19.5","Cell RNA - ASC diff [nTPM]":"13.6","Cell RNA - ASC TERT1 [nTPM]":"9.8","Cell RNA - BEWO [nTPM]":"21.1","Cell RNA - BJ [nTPM]":"12.9","Cell RNA - BJ hTERT+ [nTPM]":"8.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.3","Cell RNA - CACO-2 [nTPM]":"16.6","Cell RNA - CAPAN-2 [nTPM]":"10.4","Cell RNA - Daudi [nTPM]":"22.7","Cell RNA - EFO-21 [nTPM]":"29.1","Cell RNA - fHDF\/TERT166 [nTPM]":"10.8","Cell RNA - GAMG [nTPM]":"11.9","Cell RNA - HaCaT [nTPM]":"21.3","Cell RNA - HAP1 [nTPM]":"21.0","Cell RNA - HBEC3-KT [nTPM]":"15.4","Cell RNA - HBF TERT88 [nTPM]":"13.0","Cell RNA - HDLM-2 [nTPM]":"10.9","Cell RNA - HEK 293 [nTPM]":"10.3","Cell RNA - HEL [nTPM]":"43.0","Cell RNA - HeLa [nTPM]":"22.2","Cell RNA - Hep G2 [nTPM]":"20.7","Cell RNA - HHSteC [nTPM]":"7.0","Cell RNA - HL-60 [nTPM]":"13.3","Cell RNA - HMC-1 [nTPM]":"10.3","Cell RNA - HSkMC [nTPM]":"9.8","Cell RNA - hTCEpi [nTPM]":"5.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.3","Cell RNA - hTERT-HME1 [nTPM]":"11.7","Cell RNA - hTERT-RPE1 [nTPM]":"6.0","Cell RNA - HUVEC TERT2 [nTPM]":"12.6","Cell RNA - JURKAT [nTPM]":"18.4","Cell RNA - K-562 [nTPM]":"13.1","Cell RNA - Karpas-707 [nTPM]":"23.1","Cell RNA - LHCN-M2 [nTPM]":"8.7","Cell RNA - MCF7 [nTPM]":"36.4","Cell RNA - MOLT-4 [nTPM]":"44.6","Cell RNA - NB-4 [nTPM]":"7.8","Cell RNA - NTERA-2 [nTPM]":"17.6","Cell RNA - OE19 [nTPM]":"11.6","Cell RNA - PC-3 [nTPM]":"10.8","Cell RNA - REH [nTPM]":"19.7","Cell RNA - RH-30 [nTPM]":"17.2","Cell RNA - RPMI-8226 [nTPM]":"18.4","Cell RNA - RPTEC TERT1 [nTPM]":"7.2","Cell RNA - RT4 [nTPM]":"29.2","Cell RNA - SCLC-21H [nTPM]":"12.3","Cell RNA - SH-SY5Y [nTPM]":"12.4","Cell RNA - SiHa [nTPM]":"14.6","Cell RNA - SK-BR-3 [nTPM]":"17.7","Cell RNA - SK-MEL-30 [nTPM]":"11.1","Cell RNA - SuSa [nTPM]":"10.9","Cell RNA - T-47d [nTPM]":"26.8","Cell RNA - THP-1 [nTPM]":"11.7","Cell RNA - TIME [nTPM]":"12.4","Cell RNA - U-138 MG [nTPM]":"14.6","Cell RNA - U-2 OS [nTPM]":"11.4","Cell RNA - U-2197 [nTPM]":"15.7","Cell RNA - U-251 MG [nTPM]":"17.2","Cell RNA - U-266\/70 [nTPM]":"19.6","Cell RNA - U-266\/84 [nTPM]":"19.7","Cell RNA - U-698 [nTPM]":"33.2","Cell RNA - U-87 MG [nTPM]":"14.3","Cell RNA - U-937 [nTPM]":"15.8","Cell RNA - WM-115 [nTPM]":"11.9","Blood RNA - basophil [nTPM]":"30.0","Blood RNA - classical monocyte [nTPM]":"7.3","Blood RNA - eosinophil [nTPM]":"8.8","Blood RNA - gdT-cell [nTPM]":"12.2","Blood RNA - intermediate monocyte [nTPM]":"8.0","Blood RNA - MAIT T-cell [nTPM]":"10.9","Blood RNA - memory B-cell [nTPM]":"6.3","Blood RNA - memory CD4 T-cell [nTPM]":"10.1","Blood RNA - memory CD8 T-cell [nTPM]":"8.8","Blood RNA - myeloid DC [nTPM]":"6.6","Blood RNA - naive B-cell [nTPM]":"6.6","Blood RNA - naive CD4 T-cell [nTPM]":"8.8","Blood RNA - naive CD8 T-cell [nTPM]":"9.4","Blood RNA - neutrophil [nTPM]":"8.0","Blood RNA - NK-cell [nTPM]":"8.7","Blood RNA - non-classical monocyte [nTPM]":"12.2","Blood RNA - plasmacytoid DC [nTPM]":"6.2","Blood RNA - T-reg [nTPM]":"7.0","Blood RNA - total PBMC [nTPM]":"7.5","Brain RNA - amygdala [nTPM]":"3.9","Brain RNA - basal ganglia [nTPM]":"4.2","Brain RNA - cerebellum [nTPM]":"5.9","Brain RNA - cerebral cortex [nTPM]":"4.3","Brain RNA - hippocampal formation [nTPM]":"3.2","Brain RNA - hypothalamus [nTPM]":"6.3","Brain RNA - medulla oblongata [nTPM]":"6.1","Brain RNA - midbrain [nTPM]":"5.2","Brain RNA - pons [nTPM]":"6.5","Brain RNA - spinal cord [nTPM]":"4.9","Brain RNA - thalamus [nTPM]":"6.0","Brain RNA - white matter [nTPM]":"6.0","Single Cell Type RNA - Adipocytes [nTPM]":"34.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"37.5","Single Cell Type RNA - Astrocytes [nTPM]":"16.0","Single Cell Type RNA - B-cells [nTPM]":"37.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"100.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"49.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"52.3","Single Cell Type RNA - Bipolar cells [nTPM]":"36.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"21.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"20.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"60.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.6","Single Cell Type RNA - dendritic cells [nTPM]":"76.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"25.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"14.0","Single Cell Type RNA - Early spermatids [nTPM]":"199.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.8","Single Cell Type RNA - Endothelial cells [nTPM]":"33.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.4","Single Cell Type RNA - Erythroid cells [nTPM]":"14.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"33.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.6","Single Cell Type RNA - Fibroblasts [nTPM]":"27.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.0","Single Cell Type RNA - granulocytes [nTPM]":"50.1","Single Cell Type RNA - Granulosa cells [nTPM]":"24.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"24.3","Single Cell Type RNA - Hepatocytes [nTPM]":"25.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.9","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"36.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.5","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"32.4","Single Cell Type RNA - Langerhans cells [nTPM]":"98.8","Single Cell Type RNA - Late spermatids [nTPM]":"459.7","Single Cell Type RNA - Leydig cells [nTPM]":"20.2","Single Cell Type RNA - Macrophages [nTPM]":"33.9","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"28.1","Single Cell Type RNA - monocytes [nTPM]":"38.2","Single Cell Type RNA - Muller glia cells [nTPM]":"12.7","Single Cell Type RNA - NK-cells [nTPM]":"42.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"25.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"27.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.5","Single Cell Type RNA - Paneth cells [nTPM]":"17.3","Single Cell Type RNA - Peritubular cells [nTPM]":"20.7","Single Cell Type RNA - Plasma cells [nTPM]":"37.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"27.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"39.8","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"25.7","Single Cell Type RNA - Spermatocytes [nTPM]":"13.8","Single Cell Type RNA - Spermatogonia [nTPM]":"54.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"55.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"126.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.7","Single Cell Type RNA - T-cells [nTPM]":"63.7","Single Cell Type RNA - Theca cells [nTPM]":"20.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"22.4","Single Cell Type RNA - Urothelial cells [nTPM]":"50.3"},{"Gene":"RNF170","Gene synonym":["ADSA","DKFZP564A022","SNAX1"],"Ensembl":"ENSG00000120925","Gene description":"Ring finger protein 170","Uniprot":["Q96K19"],"Chromosome":"8","Position":"42849637-42897290","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"89.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050931","HPA054621"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA050931":"AB_2681279","HPA054621":"AB_2682545"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.3","Tissue RNA - adrenal gland [nTPM]":"11.7","Tissue RNA - amygdala [nTPM]":"14.5","Tissue RNA - appendix [nTPM]":"7.5","Tissue RNA - basal ganglia [nTPM]":"15.6","Tissue RNA - bone marrow [nTPM]":"2.4","Tissue RNA - breast [nTPM]":"12.7","Tissue RNA - cerebellum [nTPM]":"16.3","Tissue RNA - cerebral cortex [nTPM]":"16.8","Tissue RNA - cervix [nTPM]":"7.9","Tissue RNA - choroid plexus [nTPM]":"11.5","Tissue RNA - colon [nTPM]":"11.1","Tissue RNA - duodenum [nTPM]":"10.3","Tissue RNA - endometrium 1 [nTPM]":"9.5","Tissue RNA - epididymis [nTPM]":"14.9","Tissue RNA - esophagus [nTPM]":"14.2","Tissue RNA - fallopian tube [nTPM]":"9.3","Tissue RNA - gallbladder [nTPM]":"9.2","Tissue RNA - heart muscle [nTPM]":"7.7","Tissue RNA - hippocampal formation [nTPM]":"14.1","Tissue RNA - hypothalamus [nTPM]":"15.8","Tissue RNA - kidney [nTPM]":"16.4","Tissue RNA - liver [nTPM]":"19.7","Tissue RNA - lung [nTPM]":"9.3","Tissue RNA - lymph node [nTPM]":"9.4","Tissue RNA - medulla oblongata [nTPM]":"15.9","Tissue RNA - midbrain [nTPM]":"15.5","Tissue RNA - ovary [nTPM]":"12.3","Tissue RNA - pancreas [nTPM]":"8.1","Tissue RNA - parathyroid gland [nTPM]":"13.5","Tissue RNA - pituitary gland [nTPM]":"9.5","Tissue RNA - placenta [nTPM]":"19.2","Tissue RNA - pons [nTPM]":"16.2","Tissue RNA - prostate [nTPM]":"11.0","Tissue RNA - rectum [nTPM]":"11.3","Tissue RNA - retina [nTPM]":"35.6","Tissue RNA - salivary gland [nTPM]":"11.0","Tissue RNA - seminal vesicle [nTPM]":"10.6","Tissue RNA - skeletal muscle [nTPM]":"11.9","Tissue RNA - skin 1 [nTPM]":"15.1","Tissue RNA - small intestine [nTPM]":"11.4","Tissue RNA - smooth muscle [nTPM]":"7.6","Tissue RNA - spinal cord [nTPM]":"15.0","Tissue RNA - spleen [nTPM]":"9.1","Tissue RNA - stomach 1 [nTPM]":"10.7","Tissue RNA - testis [nTPM]":"5.9","Tissue RNA - thalamus [nTPM]":"15.6","Tissue RNA - thymus [nTPM]":"6.1","Tissue RNA - thyroid gland [nTPM]":"28.8","Tissue RNA - tongue [nTPM]":"9.2","Tissue RNA - tonsil [nTPM]":"9.9","Tissue RNA - urinary bladder [nTPM]":"7.6","Tissue RNA - vagina [nTPM]":"8.5","Tissue RNA - white matter [nTPM]":"18.3","Cell RNA - A-431 [nTPM]":"11.4","Cell RNA - A549 [nTPM]":"18.1","Cell RNA - AF22 [nTPM]":"18.2","Cell RNA - AN3-CA [nTPM]":"9.2","Cell RNA - ASC diff [nTPM]":"29.4","Cell RNA - ASC TERT1 [nTPM]":"29.7","Cell RNA - BEWO [nTPM]":"10.8","Cell RNA - BJ [nTPM]":"13.3","Cell RNA - BJ hTERT+ [nTPM]":"18.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.2","Cell RNA - CACO-2 [nTPM]":"8.5","Cell RNA - CAPAN-2 [nTPM]":"36.0","Cell RNA - Daudi [nTPM]":"13.6","Cell RNA - EFO-21 [nTPM]":"15.7","Cell RNA - fHDF\/TERT166 [nTPM]":"12.8","Cell RNA - GAMG [nTPM]":"22.1","Cell RNA - HaCaT [nTPM]":"9.6","Cell RNA - HAP1 [nTPM]":"9.6","Cell RNA - HBEC3-KT [nTPM]":"13.2","Cell RNA - HBF TERT88 [nTPM]":"10.8","Cell RNA - HDLM-2 [nTPM]":"9.4","Cell RNA - HEK 293 [nTPM]":"10.4","Cell RNA - HEL [nTPM]":"15.9","Cell RNA - HeLa [nTPM]":"8.5","Cell RNA - Hep G2 [nTPM]":"9.3","Cell RNA - HHSteC [nTPM]":"16.1","Cell RNA - HL-60 [nTPM]":"2.0","Cell RNA - HMC-1 [nTPM]":"10.9","Cell RNA - HSkMC [nTPM]":"26.0","Cell RNA - hTCEpi [nTPM]":"20.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.3","Cell RNA - hTERT-HME1 [nTPM]":"18.8","Cell RNA - hTERT-RPE1 [nTPM]":"16.0","Cell RNA - HUVEC TERT2 [nTPM]":"13.3","Cell RNA - JURKAT [nTPM]":"15.0","Cell RNA - K-562 [nTPM]":"14.6","Cell RNA - Karpas-707 [nTPM]":"15.8","Cell RNA - LHCN-M2 [nTPM]":"19.9","Cell RNA - MCF7 [nTPM]":"3.4","Cell RNA - MOLT-4 [nTPM]":"17.0","Cell RNA - NB-4 [nTPM]":"9.5","Cell RNA - NTERA-2 [nTPM]":"8.6","Cell RNA - OE19 [nTPM]":"24.1","Cell RNA - PC-3 [nTPM]":"6.5","Cell RNA - REH [nTPM]":"8.7","Cell RNA - RH-30 [nTPM]":"24.2","Cell RNA - RPMI-8226 [nTPM]":"7.7","Cell RNA - RPTEC TERT1 [nTPM]":"19.6","Cell RNA - RT4 [nTPM]":"10.8","Cell RNA - SCLC-21H [nTPM]":"4.7","Cell RNA - SH-SY5Y [nTPM]":"14.3","Cell RNA - SiHa [nTPM]":"12.8","Cell RNA - SK-BR-3 [nTPM]":"8.9","Cell RNA - SK-MEL-30 [nTPM]":"23.0","Cell RNA - SuSa [nTPM]":"17.7","Cell RNA - T-47d [nTPM]":"23.1","Cell RNA - THP-1 [nTPM]":"9.5","Cell RNA - TIME [nTPM]":"19.5","Cell RNA - U-138 MG [nTPM]":"13.2","Cell RNA - U-2 OS [nTPM]":"5.8","Cell RNA - U-2197 [nTPM]":"17.8","Cell RNA - U-251 MG [nTPM]":"4.3","Cell RNA - U-266\/70 [nTPM]":"25.2","Cell RNA - U-266\/84 [nTPM]":"26.4","Cell RNA - U-698 [nTPM]":"15.7","Cell RNA - U-87 MG [nTPM]":"18.2","Cell RNA - U-937 [nTPM]":"6.7","Cell RNA - WM-115 [nTPM]":"13.6","Blood RNA - basophil [nTPM]":"1.4","Blood RNA - classical monocyte [nTPM]":"5.7","Blood RNA - eosinophil [nTPM]":"2.1","Blood RNA - gdT-cell [nTPM]":"2.9","Blood RNA - intermediate monocyte [nTPM]":"5.7","Blood RNA - MAIT T-cell [nTPM]":"4.2","Blood RNA - memory B-cell [nTPM]":"6.6","Blood RNA - memory CD4 T-cell [nTPM]":"4.8","Blood RNA - memory CD8 T-cell [nTPM]":"5.3","Blood RNA - myeloid DC [nTPM]":"8.8","Blood RNA - naive B-cell [nTPM]":"3.9","Blood RNA - naive CD4 T-cell [nTPM]":"5.6","Blood RNA - naive CD8 T-cell [nTPM]":"4.1","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"4.9","Blood RNA - non-classical monocyte [nTPM]":"5.5","Blood RNA - plasmacytoid DC [nTPM]":"8.9","Blood RNA - T-reg [nTPM]":"6.7","Blood RNA - total PBMC [nTPM]":"4.5","Brain RNA - amygdala [nTPM]":"14.5","Brain RNA - basal ganglia [nTPM]":"15.6","Brain RNA - cerebellum [nTPM]":"16.3","Brain RNA - cerebral cortex [nTPM]":"16.8","Brain RNA - hippocampal formation [nTPM]":"14.1","Brain RNA - hypothalamus [nTPM]":"15.8","Brain RNA - medulla oblongata [nTPM]":"15.9","Brain RNA - midbrain [nTPM]":"15.5","Brain RNA - pons [nTPM]":"16.2","Brain RNA - spinal cord [nTPM]":"15.0","Brain RNA - thalamus [nTPM]":"15.6","Brain RNA - white matter [nTPM]":"18.3","Single Cell Type RNA - Adipocytes [nTPM]":"13.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.5","Single Cell Type RNA - Astrocytes [nTPM]":"41.1","Single Cell Type RNA - B-cells [nTPM]":"16.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"44.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"29.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"89.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"41.6","Single Cell Type RNA - dendritic cells [nTPM]":"9.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"22.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"21.6","Single Cell Type RNA - Early spermatids [nTPM]":"1.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.5","Single Cell Type RNA - Endothelial cells [nTPM]":"15.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"5.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"36.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"27.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.4","Single Cell Type RNA - Fibroblasts [nTPM]":"20.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.3","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"25.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.8","Single Cell Type RNA - Hepatocytes [nTPM]":"21.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.9","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"43.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.3","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"18.5","Single Cell Type RNA - Langerhans cells [nTPM]":"9.2","Single Cell Type RNA - Late spermatids [nTPM]":"2.4","Single Cell Type RNA - Leydig cells [nTPM]":"15.2","Single Cell Type RNA - Macrophages [nTPM]":"15.4","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"21.9","Single Cell Type RNA - Muller glia cells [nTPM]":"31.8","Single Cell Type RNA - NK-cells [nTPM]":"30.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"36.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"75.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"32.2","Single Cell Type RNA - Paneth cells [nTPM]":"18.4","Single Cell Type RNA - Peritubular cells [nTPM]":"20.7","Single Cell Type RNA - Plasma cells [nTPM]":"10.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"34.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"72.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.1","Single Cell Type RNA - Spermatocytes [nTPM]":"14.9","Single Cell Type RNA - Spermatogonia [nTPM]":"19.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"31.2","Single Cell Type RNA - T-cells [nTPM]":"12.8","Single Cell Type RNA - Theca cells [nTPM]":"25.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.6","Single Cell Type RNA - Urothelial cells [nTPM]":"12.2"},{"Gene":"RNF213","Gene synonym":["ALO17","C17orf27","KIAA1554","KIAA1618","MYMY2","NET57"],"Ensembl":"ENSG00000173821","Gene description":"Ring finger protein 213","Uniprot":["Q63HN8"],"Chromosome":"17","Position":"80260866-80398786","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Angiogenesis","Ubl conjugation pathway"],"Molecular function":["Hydrolase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"396.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"90.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003347","HPA026790"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3500","Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA003347":"AB_1079204","HPA026790":"AB_10602296"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.97e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.65e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.4","Tissue RNA - adrenal gland [nTPM]":"9.9","Tissue RNA - amygdala [nTPM]":"6.8","Tissue RNA - appendix [nTPM]":"18.6","Tissue RNA - basal ganglia [nTPM]":"12.9","Tissue RNA - bone marrow [nTPM]":"25.6","Tissue RNA - breast [nTPM]":"7.0","Tissue RNA - cerebellum [nTPM]":"9.0","Tissue RNA - cerebral cortex [nTPM]":"11.3","Tissue RNA - cervix [nTPM]":"8.0","Tissue RNA - choroid plexus [nTPM]":"13.0","Tissue RNA - colon [nTPM]":"9.0","Tissue RNA - duodenum [nTPM]":"8.7","Tissue RNA - endometrium 1 [nTPM]":"7.8","Tissue RNA - epididymis [nTPM]":"8.7","Tissue RNA - esophagus [nTPM]":"7.1","Tissue RNA - fallopian tube [nTPM]":"8.6","Tissue RNA - gallbladder [nTPM]":"10.7","Tissue RNA - heart muscle [nTPM]":"6.5","Tissue RNA - hippocampal formation [nTPM]":"5.1","Tissue RNA - hypothalamus [nTPM]":"6.9","Tissue RNA - kidney [nTPM]":"10.5","Tissue RNA - liver [nTPM]":"6.2","Tissue RNA - lung [nTPM]":"13.2","Tissue RNA - lymph node [nTPM]":"17.9","Tissue RNA - medulla oblongata [nTPM]":"23.5","Tissue RNA - midbrain [nTPM]":"11.4","Tissue RNA - ovary [nTPM]":"9.0","Tissue RNA - pancreas [nTPM]":"7.8","Tissue RNA - parathyroid gland [nTPM]":"34.2","Tissue RNA - pituitary gland [nTPM]":"6.6","Tissue RNA - placenta [nTPM]":"10.0","Tissue RNA - pons [nTPM]":"18.3","Tissue RNA - prostate [nTPM]":"7.1","Tissue RNA - rectum [nTPM]":"7.8","Tissue RNA - retina [nTPM]":"12.0","Tissue RNA - salivary gland [nTPM]":"10.8","Tissue RNA - seminal vesicle [nTPM]":"6.8","Tissue RNA - skeletal muscle [nTPM]":"6.6","Tissue RNA - skin 1 [nTPM]":"8.8","Tissue RNA - small intestine [nTPM]":"10.6","Tissue RNA - smooth muscle [nTPM]":"9.1","Tissue RNA - spinal cord [nTPM]":"13.8","Tissue RNA - spleen [nTPM]":"18.7","Tissue RNA - stomach 1 [nTPM]":"11.1","Tissue RNA - testis [nTPM]":"3.4","Tissue RNA - thalamus [nTPM]":"16.5","Tissue RNA - thymus [nTPM]":"20.2","Tissue RNA - thyroid gland [nTPM]":"11.0","Tissue RNA - tongue [nTPM]":"7.6","Tissue RNA - tonsil [nTPM]":"14.5","Tissue RNA - urinary bladder [nTPM]":"11.0","Tissue RNA - vagina [nTPM]":"7.1","Tissue RNA - white matter [nTPM]":"17.3","Cell RNA - A-431 [nTPM]":"40.1","Cell RNA - A549 [nTPM]":"69.7","Cell RNA - AF22 [nTPM]":"6.9","Cell RNA - AN3-CA [nTPM]":"4.9","Cell RNA - ASC diff [nTPM]":"24.4","Cell RNA - ASC TERT1 [nTPM]":"37.0","Cell RNA - BEWO [nTPM]":"5.1","Cell RNA - BJ [nTPM]":"9.9","Cell RNA - BJ hTERT+ [nTPM]":"21.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"43.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"37.1","Cell RNA - CACO-2 [nTPM]":"7.5","Cell RNA - CAPAN-2 [nTPM]":"18.1","Cell RNA - Daudi [nTPM]":"2.6","Cell RNA - EFO-21 [nTPM]":"8.3","Cell RNA - fHDF\/TERT166 [nTPM]":"20.8","Cell RNA - GAMG [nTPM]":"46.6","Cell RNA - HaCaT [nTPM]":"22.7","Cell RNA - HAP1 [nTPM]":"9.3","Cell RNA - HBEC3-KT [nTPM]":"12.9","Cell RNA - HBF TERT88 [nTPM]":"14.7","Cell RNA - HDLM-2 [nTPM]":"90.8","Cell RNA - HEK 293 [nTPM]":"4.3","Cell RNA - HEL [nTPM]":"6.3","Cell RNA - HeLa [nTPM]":"29.9","Cell RNA - Hep G2 [nTPM]":"13.3","Cell RNA - HHSteC [nTPM]":"10.5","Cell RNA - HL-60 [nTPM]":"6.7","Cell RNA - HMC-1 [nTPM]":"6.2","Cell RNA - HSkMC [nTPM]":"20.5","Cell RNA - hTCEpi [nTPM]":"8.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"24.6","Cell RNA - hTERT-HME1 [nTPM]":"10.6","Cell RNA - hTERT-RPE1 [nTPM]":"13.7","Cell RNA - HUVEC TERT2 [nTPM]":"34.3","Cell RNA - JURKAT [nTPM]":"28.3","Cell RNA - K-562 [nTPM]":"11.8","Cell RNA - Karpas-707 [nTPM]":"14.5","Cell RNA - LHCN-M2 [nTPM]":"16.5","Cell RNA - MCF7 [nTPM]":"9.7","Cell RNA - MOLT-4 [nTPM]":"26.7","Cell RNA - NB-4 [nTPM]":"2.8","Cell RNA - NTERA-2 [nTPM]":"5.1","Cell RNA - OE19 [nTPM]":"7.5","Cell RNA - PC-3 [nTPM]":"16.0","Cell RNA - REH [nTPM]":"18.0","Cell RNA - RH-30 [nTPM]":"15.9","Cell RNA - RPMI-8226 [nTPM]":"3.1","Cell RNA - RPTEC TERT1 [nTPM]":"12.1","Cell RNA - RT4 [nTPM]":"34.1","Cell RNA - SCLC-21H [nTPM]":"6.6","Cell RNA - SH-SY5Y [nTPM]":"9.2","Cell RNA - SiHa [nTPM]":"24.1","Cell RNA - SK-BR-3 [nTPM]":"50.3","Cell RNA - SK-MEL-30 [nTPM]":"17.3","Cell RNA - SuSa [nTPM]":"15.3","Cell RNA - T-47d [nTPM]":"11.6","Cell RNA - THP-1 [nTPM]":"8.2","Cell RNA - TIME [nTPM]":"44.5","Cell RNA - U-138 MG [nTPM]":"24.2","Cell RNA - U-2 OS [nTPM]":"19.0","Cell RNA - U-2197 [nTPM]":"14.4","Cell RNA - U-251 MG [nTPM]":"10.3","Cell RNA - U-266\/70 [nTPM]":"6.3","Cell RNA - U-266\/84 [nTPM]":"6.3","Cell RNA - U-698 [nTPM]":"7.0","Cell RNA - U-87 MG [nTPM]":"18.2","Cell RNA - U-937 [nTPM]":"7.6","Cell RNA - WM-115 [nTPM]":"8.9","Blood RNA - basophil [nTPM]":"19.5","Blood RNA - classical monocyte [nTPM]":"20.8","Blood RNA - eosinophil [nTPM]":"10.4","Blood RNA - gdT-cell [nTPM]":"26.2","Blood RNA - intermediate monocyte [nTPM]":"18.5","Blood RNA - MAIT T-cell [nTPM]":"17.5","Blood RNA - memory B-cell [nTPM]":"15.3","Blood RNA - memory CD4 T-cell [nTPM]":"18.6","Blood RNA - memory CD8 T-cell [nTPM]":"21.6","Blood RNA - myeloid DC [nTPM]":"5.4","Blood RNA - naive B-cell [nTPM]":"15.5","Blood RNA - naive CD4 T-cell [nTPM]":"14.6","Blood RNA - naive CD8 T-cell [nTPM]":"18.2","Blood RNA - neutrophil [nTPM]":"84.5","Blood RNA - NK-cell [nTPM]":"26.1","Blood RNA - non-classical monocyte [nTPM]":"17.1","Blood RNA - plasmacytoid DC [nTPM]":"32.0","Blood RNA - T-reg [nTPM]":"15.4","Blood RNA - total PBMC [nTPM]":"4.8","Brain RNA - amygdala [nTPM]":"6.8","Brain RNA - basal ganglia [nTPM]":"12.9","Brain RNA - cerebellum [nTPM]":"9.0","Brain RNA - cerebral cortex [nTPM]":"11.3","Brain RNA - hippocampal formation [nTPM]":"5.1","Brain RNA - hypothalamus [nTPM]":"6.9","Brain RNA - medulla oblongata [nTPM]":"23.5","Brain RNA - midbrain [nTPM]":"11.4","Brain RNA - pons [nTPM]":"18.3","Brain RNA - spinal cord [nTPM]":"13.8","Brain RNA - thalamus [nTPM]":"16.5","Brain RNA - white matter [nTPM]":"17.3","Single Cell Type RNA - Adipocytes [nTPM]":"76.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"89.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"56.9","Single Cell Type RNA - Astrocytes [nTPM]":"56.8","Single Cell Type RNA - B-cells [nTPM]":"89.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"35.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"37.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"39.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"43.3","Single Cell Type RNA - Bipolar cells [nTPM]":"21.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"59.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"41.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"32.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"75.8","Single Cell Type RNA - Club cells [nTPM]":"50.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"101.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"50.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"21.0","Single Cell Type RNA - dendritic cells [nTPM]":"240.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"117.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"120.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"58.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"58.9","Single Cell Type RNA - Endothelial cells [nTPM]":"90.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"46.0","Single Cell Type RNA - Erythroid cells [nTPM]":"30.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"162.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"31.5","Single Cell Type RNA - Fibroblasts [nTPM]":"50.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"158.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"93.4","Single Cell Type RNA - granulocytes [nTPM]":"46.7","Single Cell Type RNA - Granulosa cells [nTPM]":"140.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"74.3","Single Cell Type RNA - Hepatocytes [nTPM]":"56.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"98.0","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"68.2","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"136.5","Single Cell Type RNA - Langerhans cells [nTPM]":"94.9","Single Cell Type RNA - Late spermatids [nTPM]":"3.7","Single Cell Type RNA - Leydig cells [nTPM]":"60.9","Single Cell Type RNA - Macrophages [nTPM]":"128.9","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"87.1","Single Cell Type RNA - monocytes [nTPM]":"194.6","Single Cell Type RNA - Muller glia cells [nTPM]":"26.1","Single Cell Type RNA - NK-cells [nTPM]":"396.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"32.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"70.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"166.1","Single Cell Type RNA - Paneth cells [nTPM]":"76.2","Single Cell Type RNA - Peritubular cells [nTPM]":"51.6","Single Cell Type RNA - Plasma cells [nTPM]":"167.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"100.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"116.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"92.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"66.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"68.5","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"52.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"53.7","Single Cell Type RNA - Spermatocytes [nTPM]":"1.4","Single Cell Type RNA - Spermatogonia [nTPM]":"8.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"43.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"34.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"21.8","Single Cell Type RNA - T-cells [nTPM]":"211.6","Single Cell Type RNA - Theca cells [nTPM]":"84.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"54.9","Single Cell Type RNA - Urothelial cells [nTPM]":"66.5"},{"Gene":"RNF216","Gene synonym":["TRIAD3","UBCE7IP1","ZIN"],"Ensembl":"ENSG00000011275","Gene description":"Ring finger protein 216","Uniprot":["Q9NWF9"],"Chromosome":"7","Position":"5620047-5781696","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Host-virus interaction","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Hypogonadotropic hypogonadism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"145.5","Late spermatids":"257.6","Spermatocytes":"159.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018955","HPA021123"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA018955":"AB_1858500","HPA021123":"AB_1858501"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.26e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.24e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-3"},"Tissue RNA - adipose tissue [nTPM]":"14.3","Tissue RNA - adrenal gland [nTPM]":"12.3","Tissue RNA - amygdala [nTPM]":"14.3","Tissue RNA - appendix [nTPM]":"12.8","Tissue RNA - basal ganglia [nTPM]":"15.9","Tissue RNA - bone marrow [nTPM]":"15.6","Tissue RNA - breast [nTPM]":"13.1","Tissue RNA - cerebellum [nTPM]":"12.6","Tissue RNA - cerebral cortex [nTPM]":"14.6","Tissue RNA - cervix [nTPM]":"13.2","Tissue RNA - choroid plexus [nTPM]":"10.0","Tissue RNA - colon [nTPM]":"25.5","Tissue RNA - duodenum [nTPM]":"8.1","Tissue RNA - endometrium 1 [nTPM]":"21.9","Tissue RNA - epididymis [nTPM]":"8.2","Tissue RNA - esophagus [nTPM]":"12.3","Tissue RNA - fallopian tube [nTPM]":"15.8","Tissue RNA - gallbladder [nTPM]":"8.7","Tissue RNA - heart muscle [nTPM]":"21.7","Tissue RNA - hippocampal formation [nTPM]":"13.8","Tissue RNA - hypothalamus [nTPM]":"17.5","Tissue RNA - kidney [nTPM]":"10.0","Tissue RNA - liver [nTPM]":"10.1","Tissue RNA - lung [nTPM]":"12.8","Tissue RNA - lymph node [nTPM]":"17.0","Tissue RNA - medulla oblongata [nTPM]":"14.9","Tissue RNA - midbrain [nTPM]":"15.4","Tissue RNA - ovary [nTPM]":"16.5","Tissue RNA - pancreas [nTPM]":"14.9","Tissue RNA - parathyroid gland [nTPM]":"13.9","Tissue RNA - pituitary gland [nTPM]":"15.4","Tissue RNA - placenta [nTPM]":"7.7","Tissue RNA - pons [nTPM]":"14.8","Tissue RNA - prostate [nTPM]":"14.6","Tissue RNA - rectum [nTPM]":"5.8","Tissue RNA - retina [nTPM]":"7.2","Tissue RNA - salivary gland [nTPM]":"11.4","Tissue RNA - seminal vesicle [nTPM]":"13.7","Tissue RNA - skeletal muscle [nTPM]":"19.6","Tissue RNA - skin 1 [nTPM]":"13.3","Tissue RNA - small intestine [nTPM]":"17.9","Tissue RNA - smooth muscle [nTPM]":"15.0","Tissue RNA - spinal cord [nTPM]":"12.8","Tissue RNA - spleen [nTPM]":"19.2","Tissue RNA - stomach 1 [nTPM]":"14.6","Tissue RNA - testis [nTPM]":"30.1","Tissue RNA - thalamus [nTPM]":"16.2","Tissue RNA - thymus [nTPM]":"12.8","Tissue RNA - thyroid gland [nTPM]":"12.7","Tissue RNA - tongue [nTPM]":"11.9","Tissue RNA - tonsil [nTPM]":"11.5","Tissue RNA - urinary bladder [nTPM]":"16.4","Tissue RNA - vagina [nTPM]":"10.9","Tissue RNA - white matter [nTPM]":"14.3","Cell RNA - A-431 [nTPM]":"22.0","Cell RNA - A549 [nTPM]":"23.6","Cell RNA - AF22 [nTPM]":"17.0","Cell RNA - AN3-CA [nTPM]":"32.8","Cell RNA - ASC diff [nTPM]":"21.6","Cell RNA - ASC TERT1 [nTPM]":"14.6","Cell RNA - BEWO [nTPM]":"11.5","Cell RNA - BJ [nTPM]":"20.7","Cell RNA - BJ hTERT+ [nTPM]":"19.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.8","Cell RNA - CACO-2 [nTPM]":"16.7","Cell RNA - CAPAN-2 [nTPM]":"12.3","Cell RNA - Daudi [nTPM]":"17.3","Cell RNA - EFO-21 [nTPM]":"11.4","Cell RNA - fHDF\/TERT166 [nTPM]":"22.0","Cell RNA - GAMG [nTPM]":"38.7","Cell RNA - HaCaT [nTPM]":"17.1","Cell RNA - HAP1 [nTPM]":"13.6","Cell RNA - HBEC3-KT [nTPM]":"15.3","Cell RNA - HBF TERT88 [nTPM]":"10.3","Cell RNA - HDLM-2 [nTPM]":"11.4","Cell RNA - HEK 293 [nTPM]":"19.3","Cell RNA - HEL [nTPM]":"12.5","Cell RNA - HeLa [nTPM]":"13.6","Cell RNA - Hep G2 [nTPM]":"18.0","Cell RNA - HHSteC [nTPM]":"27.7","Cell RNA - HL-60 [nTPM]":"19.5","Cell RNA - HMC-1 [nTPM]":"25.3","Cell RNA - HSkMC [nTPM]":"21.4","Cell RNA - hTCEpi [nTPM]":"20.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.2","Cell RNA - hTERT-HME1 [nTPM]":"14.6","Cell RNA - hTERT-RPE1 [nTPM]":"18.4","Cell RNA - HUVEC TERT2 [nTPM]":"15.0","Cell RNA - JURKAT [nTPM]":"19.2","Cell RNA - K-562 [nTPM]":"28.4","Cell RNA - Karpas-707 [nTPM]":"12.9","Cell RNA - LHCN-M2 [nTPM]":"18.9","Cell RNA - MCF7 [nTPM]":"35.2","Cell RNA - MOLT-4 [nTPM]":"8.8","Cell RNA - NB-4 [nTPM]":"44.7","Cell RNA - NTERA-2 [nTPM]":"25.7","Cell RNA - OE19 [nTPM]":"13.1","Cell RNA - PC-3 [nTPM]":"20.0","Cell RNA - REH [nTPM]":"26.1","Cell RNA - RH-30 [nTPM]":"23.4","Cell RNA - RPMI-8226 [nTPM]":"12.2","Cell RNA - RPTEC TERT1 [nTPM]":"13.9","Cell RNA - RT4 [nTPM]":"13.9","Cell RNA - SCLC-21H [nTPM]":"14.1","Cell RNA - SH-SY5Y [nTPM]":"25.3","Cell RNA - SiHa [nTPM]":"11.8","Cell RNA - SK-BR-3 [nTPM]":"33.9","Cell RNA - SK-MEL-30 [nTPM]":"13.2","Cell RNA - SuSa [nTPM]":"15.3","Cell RNA - T-47d [nTPM]":"14.2","Cell RNA - THP-1 [nTPM]":"28.2","Cell RNA - TIME [nTPM]":"20.5","Cell RNA - U-138 MG [nTPM]":"24.9","Cell RNA - U-2 OS [nTPM]":"39.9","Cell RNA - U-2197 [nTPM]":"25.2","Cell RNA - U-251 MG [nTPM]":"22.8","Cell RNA - U-266\/70 [nTPM]":"11.4","Cell RNA - U-266\/84 [nTPM]":"9.0","Cell RNA - U-698 [nTPM]":"16.0","Cell RNA - U-87 MG [nTPM]":"19.6","Cell RNA - U-937 [nTPM]":"21.7","Cell RNA - WM-115 [nTPM]":"37.4","Blood RNA - basophil [nTPM]":"3.5","Blood RNA - classical monocyte [nTPM]":"7.7","Blood RNA - eosinophil [nTPM]":"24.2","Blood RNA - gdT-cell [nTPM]":"10.1","Blood RNA - intermediate monocyte [nTPM]":"8.3","Blood RNA - MAIT T-cell [nTPM]":"9.4","Blood RNA - memory B-cell [nTPM]":"8.3","Blood RNA - memory CD4 T-cell [nTPM]":"9.3","Blood RNA - memory CD8 T-cell [nTPM]":"8.7","Blood RNA - myeloid DC [nTPM]":"6.3","Blood RNA - naive B-cell [nTPM]":"8.8","Blood RNA - naive CD4 T-cell [nTPM]":"10.9","Blood RNA - naive CD8 T-cell [nTPM]":"11.3","Blood RNA - neutrophil [nTPM]":"13.2","Blood RNA - NK-cell [nTPM]":"12.7","Blood RNA - non-classical monocyte [nTPM]":"8.7","Blood RNA - plasmacytoid DC [nTPM]":"7.1","Blood RNA - T-reg [nTPM]":"8.3","Blood RNA - total PBMC [nTPM]":"6.9","Brain RNA - amygdala [nTPM]":"14.3","Brain RNA - basal ganglia [nTPM]":"15.9","Brain RNA - cerebellum [nTPM]":"12.6","Brain RNA - cerebral cortex [nTPM]":"14.6","Brain RNA - hippocampal formation [nTPM]":"13.8","Brain RNA - hypothalamus [nTPM]":"17.5","Brain RNA - medulla oblongata [nTPM]":"14.9","Brain RNA - midbrain [nTPM]":"15.4","Brain RNA - pons [nTPM]":"14.8","Brain RNA - spinal cord [nTPM]":"12.8","Brain RNA - thalamus [nTPM]":"16.2","Brain RNA - white matter [nTPM]":"14.3","Single Cell Type RNA - Adipocytes [nTPM]":"33.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.9","Single Cell Type RNA - Astrocytes [nTPM]":"34.9","Single Cell Type RNA - B-cells [nTPM]":"33.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Bipolar cells [nTPM]":"36.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"33.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"13.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.1","Single Cell Type RNA - dendritic cells [nTPM]":"47.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"25.4","Single Cell Type RNA - Ductal cells [nTPM]":"17.6","Single Cell Type RNA - Early spermatids [nTPM]":"145.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"33.7","Single Cell Type RNA - Endothelial cells [nTPM]":"29.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"8.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"50.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.9","Single Cell Type RNA - Fibroblasts [nTPM]":"26.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.9","Single Cell Type RNA - granulocytes [nTPM]":"19.6","Single Cell Type RNA - Granulosa cells [nTPM]":"34.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.4","Single Cell Type RNA - Hepatocytes [nTPM]":"15.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.9","Single Cell Type RNA - Horizontal cells [nTPM]":"28.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"61.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.4","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"23.0","Single Cell Type RNA - Langerhans cells [nTPM]":"29.3","Single Cell Type RNA - Late spermatids [nTPM]":"257.6","Single Cell Type RNA - Leydig cells [nTPM]":"37.3","Single Cell Type RNA - Macrophages [nTPM]":"23.1","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"49.6","Single Cell Type RNA - monocytes [nTPM]":"37.0","Single Cell Type RNA - Muller glia cells [nTPM]":"30.2","Single Cell Type RNA - NK-cells [nTPM]":"56.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"46.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"64.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.6","Single Cell Type RNA - Paneth cells [nTPM]":"7.0","Single Cell Type RNA - Peritubular cells [nTPM]":"30.1","Single Cell Type RNA - Plasma cells [nTPM]":"20.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"24.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"48.5","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"46.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"30.0","Single Cell Type RNA - Spermatocytes [nTPM]":"159.8","Single Cell Type RNA - Spermatogonia [nTPM]":"124.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.2","Single Cell Type RNA - T-cells [nTPM]":"40.2","Single Cell Type RNA - Theca cells [nTPM]":"22.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.8","Single Cell Type RNA - Urothelial cells [nTPM]":"15.2"},{"Gene":"RNF43","Gene synonym":["DKFZp781H0392","FLJ20315","URCC"],"Ensembl":"ENSG00000108375","Gene description":"Ring finger protein 43","Uniprot":["Q68DV7"],"Chromosome":"17","Position":"58353676-58417595","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway","Wnt signaling pathway"],"Molecular function":["Developmental protein","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"22.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"67.7","Intestinal goblet cells":"41.6","Undifferentiated cells":"63.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"colorectal cancer":"41.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"17.0","CACO-2":"24.7","Hep G2":"49.4","OE19":"54.7"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008079"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA008079":"AB_1856371"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.04e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"10.9","Tissue RNA - amygdala [nTPM]":"1.7","Tissue RNA - appendix [nTPM]":"2.0","Tissue RNA - basal ganglia [nTPM]":"3.1","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"5.5","Tissue RNA - cerebellum [nTPM]":"9.6","Tissue RNA - cerebral cortex [nTPM]":"2.7","Tissue RNA - cervix [nTPM]":"2.6","Tissue RNA - choroid plexus [nTPM]":"1.5","Tissue RNA - colon [nTPM]":"13.4","Tissue RNA - duodenum [nTPM]":"22.7","Tissue RNA - endometrium 1 [nTPM]":"1.7","Tissue RNA - epididymis [nTPM]":"4.4","Tissue RNA - esophagus [nTPM]":"10.4","Tissue RNA - fallopian tube [nTPM]":"4.8","Tissue RNA - gallbladder [nTPM]":"2.7","Tissue RNA - heart muscle [nTPM]":"2.7","Tissue RNA - hippocampal formation [nTPM]":"2.0","Tissue RNA - hypothalamus [nTPM]":"1.3","Tissue RNA - kidney [nTPM]":"6.1","Tissue RNA - liver [nTPM]":"9.1","Tissue RNA - lung [nTPM]":"3.6","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"1.8","Tissue RNA - midbrain [nTPM]":"3.4","Tissue RNA - ovary [nTPM]":"0.9","Tissue RNA - pancreas [nTPM]":"8.2","Tissue RNA - parathyroid gland [nTPM]":"5.2","Tissue RNA - pituitary gland [nTPM]":"4.3","Tissue RNA - placenta [nTPM]":"4.8","Tissue RNA - pons [nTPM]":"1.9","Tissue RNA - prostate [nTPM]":"9.4","Tissue RNA - rectum [nTPM]":"19.3","Tissue RNA - retina [nTPM]":"1.2","Tissue RNA - salivary gland [nTPM]":"9.3","Tissue RNA - seminal vesicle [nTPM]":"4.8","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"11.3","Tissue RNA - small intestine [nTPM]":"16.9","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"1.4","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"5.8","Tissue RNA - testis [nTPM]":"3.4","Tissue RNA - thalamus [nTPM]":"2.3","Tissue RNA - thymus [nTPM]":"3.7","Tissue RNA - thyroid gland [nTPM]":"1.9","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"1.5","Tissue RNA - urinary bladder [nTPM]":"2.1","Tissue RNA - vagina [nTPM]":"5.2","Tissue RNA - white matter [nTPM]":"1.4","Cell RNA - A-431 [nTPM]":"1.1","Cell RNA - A549 [nTPM]":"17.0","Cell RNA - AF22 [nTPM]":"2.7","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"9.3","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"24.7","Cell RNA - CAPAN-2 [nTPM]":"8.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"8.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"1.9","Cell RNA - HaCaT [nTPM]":"4.6","Cell RNA - HAP1 [nTPM]":"0.6","Cell RNA - HBEC3-KT [nTPM]":"6.8","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"8.6","Cell RNA - HEK 293 [nTPM]":"11.3","Cell RNA - HEL [nTPM]":"1.9","Cell RNA - HeLa [nTPM]":"0.8","Cell RNA - Hep G2 [nTPM]":"49.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"13.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"2.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"54.7","Cell RNA - PC-3 [nTPM]":"1.0","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"2.2","Cell RNA - RPTEC TERT1 [nTPM]":"5.9","Cell RNA - RT4 [nTPM]":"9.0","Cell RNA - SCLC-21H [nTPM]":"1.6","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"1.6","Cell RNA - SK-BR-3 [nTPM]":"0.7","Cell RNA - SK-MEL-30 [nTPM]":"0.5","Cell RNA - SuSa [nTPM]":"5.4","Cell RNA - T-47d [nTPM]":"2.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.8","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.6","Cell RNA - U-266\/84 [nTPM]":"1.4","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"3.8","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.7","Brain RNA - basal ganglia [nTPM]":"3.1","Brain RNA - cerebellum [nTPM]":"9.6","Brain RNA - cerebral cortex [nTPM]":"2.7","Brain RNA - hippocampal formation [nTPM]":"2.0","Brain RNA - hypothalamus [nTPM]":"1.3","Brain RNA - medulla oblongata [nTPM]":"1.8","Brain RNA - midbrain [nTPM]":"3.4","Brain RNA - pons [nTPM]":"1.9","Brain RNA - spinal cord [nTPM]":"1.4","Brain RNA - thalamus [nTPM]":"2.3","Brain RNA - white matter [nTPM]":"1.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.9","Single Cell Type RNA - Astrocytes [nTPM]":"29.0","Single Cell Type RNA - B-cells [nTPM]":"2.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"67.7","Single Cell Type RNA - Bipolar cells [nTPM]":"2.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"5.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"26.0","Single Cell Type RNA - dendritic cells [nTPM]":"2.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"33.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"5.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.5","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"7.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"11.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.6","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"41.6","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.9","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"1.3","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"2.8","Single Cell Type RNA - Muller glia cells [nTPM]":"12.0","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.2","Single Cell Type RNA - Paneth cells [nTPM]":"21.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"1.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"28.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.9","Single Cell Type RNA - T-cells [nTPM]":"3.1","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"63.6","Single Cell Type RNA - Urothelial cells [nTPM]":"6.3"},{"Gene":"RNF6","Gene synonym":["DKFZp686P0776"],"Ensembl":"ENSG00000127870","Gene description":"Ring finger protein 6","Uniprot":["Q9Y252"],"Chromosome":"13","Position":"26132115-26222314","Protein class":["Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"99.1","Late spermatids":"191.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039343","HPA040048"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA039343":"AB_2676456","HPA040048":"AB_10672969"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.07e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.35e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.47e-2"},"Tissue RNA - adipose tissue [nTPM]":"18.9","Tissue RNA - adrenal gland [nTPM]":"17.3","Tissue RNA - amygdala [nTPM]":"12.4","Tissue RNA - appendix [nTPM]":"18.7","Tissue RNA - basal ganglia [nTPM]":"13.3","Tissue RNA - bone marrow [nTPM]":"32.5","Tissue RNA - breast [nTPM]":"17.9","Tissue RNA - cerebellum [nTPM]":"13.4","Tissue RNA - cerebral cortex [nTPM]":"18.4","Tissue RNA - cervix [nTPM]":"13.4","Tissue RNA - choroid plexus [nTPM]":"13.5","Tissue RNA - colon [nTPM]":"18.4","Tissue RNA - duodenum [nTPM]":"17.5","Tissue RNA - endometrium 1 [nTPM]":"12.4","Tissue RNA - epididymis [nTPM]":"13.7","Tissue RNA - esophagus [nTPM]":"18.5","Tissue RNA - fallopian tube [nTPM]":"14.5","Tissue RNA - gallbladder [nTPM]":"13.7","Tissue RNA - heart muscle [nTPM]":"13.7","Tissue RNA - hippocampal formation [nTPM]":"13.9","Tissue RNA - hypothalamus [nTPM]":"11.7","Tissue RNA - kidney [nTPM]":"18.2","Tissue RNA - liver [nTPM]":"16.6","Tissue RNA - lung [nTPM]":"16.2","Tissue RNA - lymph node [nTPM]":"22.4","Tissue RNA - medulla oblongata [nTPM]":"10.4","Tissue RNA - midbrain [nTPM]":"13.5","Tissue RNA - ovary [nTPM]":"11.5","Tissue RNA - pancreas [nTPM]":"14.1","Tissue RNA - parathyroid gland [nTPM]":"22.3","Tissue RNA - pituitary gland [nTPM]":"10.7","Tissue RNA - placenta [nTPM]":"19.9","Tissue RNA - pons [nTPM]":"11.5","Tissue RNA - prostate [nTPM]":"16.0","Tissue RNA - rectum [nTPM]":"18.5","Tissue RNA - retina [nTPM]":"26.6","Tissue RNA - salivary gland [nTPM]":"13.5","Tissue RNA - seminal vesicle [nTPM]":"13.9","Tissue RNA - skeletal muscle [nTPM]":"21.2","Tissue RNA - skin 1 [nTPM]":"17.3","Tissue RNA - small intestine [nTPM]":"18.8","Tissue RNA - smooth muscle [nTPM]":"15.7","Tissue RNA - spinal cord [nTPM]":"10.8","Tissue RNA - spleen [nTPM]":"19.7","Tissue RNA - stomach 1 [nTPM]":"17.2","Tissue RNA - testis [nTPM]":"33.6","Tissue RNA - thalamus [nTPM]":"13.7","Tissue RNA - thymus [nTPM]":"25.3","Tissue RNA - thyroid gland [nTPM]":"17.5","Tissue RNA - tongue [nTPM]":"15.3","Tissue RNA - tonsil [nTPM]":"23.8","Tissue RNA - urinary bladder [nTPM]":"18.3","Tissue RNA - vagina [nTPM]":"10.1","Tissue RNA - white matter [nTPM]":"11.5","Cell RNA - A-431 [nTPM]":"33.3","Cell RNA - A549 [nTPM]":"28.9","Cell RNA - AF22 [nTPM]":"10.7","Cell RNA - AN3-CA [nTPM]":"15.8","Cell RNA - ASC diff [nTPM]":"36.3","Cell RNA - ASC TERT1 [nTPM]":"28.2","Cell RNA - BEWO [nTPM]":"23.9","Cell RNA - BJ [nTPM]":"56.3","Cell RNA - BJ hTERT+ [nTPM]":"45.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"35.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.9","Cell RNA - CACO-2 [nTPM]":"36.4","Cell RNA - CAPAN-2 [nTPM]":"41.8","Cell RNA - Daudi [nTPM]":"59.5","Cell RNA - EFO-21 [nTPM]":"27.3","Cell RNA - fHDF\/TERT166 [nTPM]":"53.5","Cell RNA - GAMG [nTPM]":"31.5","Cell RNA - HaCaT [nTPM]":"43.7","Cell RNA - HAP1 [nTPM]":"30.2","Cell RNA - HBEC3-KT [nTPM]":"45.3","Cell RNA - HBF TERT88 [nTPM]":"58.4","Cell RNA - HDLM-2 [nTPM]":"57.7","Cell RNA - HEK 293 [nTPM]":"19.2","Cell RNA - HEL [nTPM]":"64.8","Cell RNA - HeLa [nTPM]":"23.9","Cell RNA - Hep G2 [nTPM]":"31.3","Cell RNA - HHSteC [nTPM]":"56.6","Cell RNA - HL-60 [nTPM]":"68.7","Cell RNA - HMC-1 [nTPM]":"65.4","Cell RNA - HSkMC [nTPM]":"26.8","Cell RNA - hTCEpi [nTPM]":"86.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"39.8","Cell RNA - hTERT-HME1 [nTPM]":"84.2","Cell RNA - hTERT-RPE1 [nTPM]":"34.3","Cell RNA - HUVEC TERT2 [nTPM]":"36.0","Cell RNA - JURKAT [nTPM]":"25.5","Cell RNA - K-562 [nTPM]":"25.6","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"55.3","Cell RNA - MCF7 [nTPM]":"30.0","Cell RNA - MOLT-4 [nTPM]":"38.5","Cell RNA - NB-4 [nTPM]":"39.8","Cell RNA - NTERA-2 [nTPM]":"8.7","Cell RNA - OE19 [nTPM]":"59.5","Cell RNA - PC-3 [nTPM]":"19.8","Cell RNA - REH [nTPM]":"30.4","Cell RNA - RH-30 [nTPM]":"41.5","Cell RNA - RPMI-8226 [nTPM]":"23.7","Cell RNA - RPTEC TERT1 [nTPM]":"43.6","Cell RNA - RT4 [nTPM]":"43.3","Cell RNA - SCLC-21H [nTPM]":"19.3","Cell RNA - SH-SY5Y [nTPM]":"11.9","Cell RNA - SiHa [nTPM]":"29.9","Cell RNA - SK-BR-3 [nTPM]":"54.0","Cell RNA - SK-MEL-30 [nTPM]":"54.1","Cell RNA - SuSa [nTPM]":"24.8","Cell RNA - T-47d [nTPM]":"20.7","Cell RNA - THP-1 [nTPM]":"66.3","Cell RNA - TIME [nTPM]":"47.6","Cell RNA - U-138 MG [nTPM]":"30.4","Cell RNA - U-2 OS [nTPM]":"18.6","Cell RNA - U-2197 [nTPM]":"41.1","Cell RNA - U-251 MG [nTPM]":"40.5","Cell RNA - U-266\/70 [nTPM]":"14.8","Cell RNA - U-266\/84 [nTPM]":"14.9","Cell RNA - U-698 [nTPM]":"34.9","Cell RNA - U-87 MG [nTPM]":"27.8","Cell RNA - U-937 [nTPM]":"38.4","Cell RNA - WM-115 [nTPM]":"40.7","Blood RNA - basophil [nTPM]":"46.6","Blood RNA - classical monocyte [nTPM]":"14.5","Blood RNA - eosinophil [nTPM]":"34.7","Blood RNA - gdT-cell [nTPM]":"15.6","Blood RNA - intermediate monocyte [nTPM]":"18.4","Blood RNA - MAIT T-cell [nTPM]":"17.1","Blood RNA - memory B-cell [nTPM]":"18.6","Blood RNA - memory CD4 T-cell [nTPM]":"17.1","Blood RNA - memory CD8 T-cell [nTPM]":"17.7","Blood RNA - myeloid DC [nTPM]":"17.6","Blood RNA - naive B-cell [nTPM]":"12.5","Blood RNA - naive CD4 T-cell [nTPM]":"16.8","Blood RNA - naive CD8 T-cell [nTPM]":"14.8","Blood RNA - neutrophil [nTPM]":"9.7","Blood RNA - NK-cell [nTPM]":"20.0","Blood RNA - non-classical monocyte [nTPM]":"23.3","Blood RNA - plasmacytoid DC [nTPM]":"9.1","Blood RNA - T-reg [nTPM]":"19.2","Blood RNA - total PBMC [nTPM]":"14.2","Brain RNA - amygdala [nTPM]":"12.4","Brain RNA - basal ganglia [nTPM]":"13.3","Brain RNA - cerebellum [nTPM]":"13.4","Brain RNA - cerebral cortex [nTPM]":"18.4","Brain RNA - hippocampal formation [nTPM]":"13.9","Brain RNA - hypothalamus [nTPM]":"11.7","Brain RNA - medulla oblongata [nTPM]":"10.4","Brain RNA - midbrain [nTPM]":"13.5","Brain RNA - pons [nTPM]":"11.5","Brain RNA - spinal cord [nTPM]":"10.8","Brain RNA - thalamus [nTPM]":"13.7","Brain RNA - white matter [nTPM]":"11.5","Single Cell Type RNA - Adipocytes [nTPM]":"20.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.8","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"26.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"22.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"19.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.2","Single Cell Type RNA - dendritic cells [nTPM]":"31.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"15.1","Single Cell Type RNA - Early spermatids [nTPM]":"99.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"37.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.9","Single Cell Type RNA - Endothelial cells [nTPM]":"23.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.4","Single Cell Type RNA - Erythroid cells [nTPM]":"24.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.8","Single Cell Type RNA - Fibroblasts [nTPM]":"16.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.9","Single Cell Type RNA - granulocytes [nTPM]":"26.6","Single Cell Type RNA - Granulosa cells [nTPM]":"12.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.5","Single Cell Type RNA - Hepatocytes [nTPM]":"12.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.5","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.5","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"22.4","Single Cell Type RNA - Langerhans cells [nTPM]":"19.9","Single Cell Type RNA - Late spermatids [nTPM]":"191.0","Single Cell Type RNA - Leydig cells [nTPM]":"14.6","Single Cell Type RNA - Macrophages [nTPM]":"23.0","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"21.6","Single Cell Type RNA - Muller glia cells [nTPM]":"24.9","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"24.4","Single Cell Type RNA - Paneth cells [nTPM]":"20.1","Single Cell Type RNA - Peritubular cells [nTPM]":"11.3","Single Cell Type RNA - Plasma cells [nTPM]":"18.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"22.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"21.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"40.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"43.2","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.5","Single Cell Type RNA - Spermatocytes [nTPM]":"83.5","Single Cell Type RNA - Spermatogonia [nTPM]":"29.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"29.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"42.1","Single Cell Type RNA - T-cells [nTPM]":"26.2","Single Cell Type RNA - Theca cells [nTPM]":"17.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.6","Single Cell Type RNA - Urothelial cells [nTPM]":"23.5"},{"Gene":"ROR1","Gene synonym":["NTRKR1"],"Ensembl":"ENSG00000185483","Gene description":"Receptor tyrosine kinase like orphan receptor 1","Uniprot":["Q01973"],"Chromosome":"1","Position":"63774017-64181498","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Kinase","Receptor","Transferase"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"26.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"51.3","Astrocytes":"81.0","Inhibitory neurons":"69.7","Microglial cells":"36.5","Oligodendrocytes":"109.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"40.5","ASC TERT1":"50.3","CACO-2":"36.8","HHSteC":"38.3","HSkMC":"41.6","NTERA-2":"43.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7700000","Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.11e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.4","Tissue RNA - adrenal gland [nTPM]":"1.1","Tissue RNA - amygdala [nTPM]":"0.6","Tissue RNA - appendix [nTPM]":"2.2","Tissue RNA - basal ganglia [nTPM]":"1.4","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"3.7","Tissue RNA - cerebellum [nTPM]":"3.0","Tissue RNA - cerebral cortex [nTPM]":"0.8","Tissue RNA - cervix [nTPM]":"7.5","Tissue RNA - choroid plexus [nTPM]":"4.6","Tissue RNA - colon [nTPM]":"4.5","Tissue RNA - duodenum [nTPM]":"2.2","Tissue RNA - endometrium 1 [nTPM]":"7.1","Tissue RNA - epididymis [nTPM]":"1.4","Tissue RNA - esophagus [nTPM]":"5.2","Tissue RNA - fallopian tube [nTPM]":"2.5","Tissue RNA - gallbladder [nTPM]":"5.2","Tissue RNA - heart muscle [nTPM]":"7.5","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"2.3","Tissue RNA - liver [nTPM]":"0.5","Tissue RNA - lung [nTPM]":"7.0","Tissue RNA - lymph node [nTPM]":"1.2","Tissue RNA - medulla oblongata [nTPM]":"0.7","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"8.3","Tissue RNA - pancreas [nTPM]":"5.5","Tissue RNA - parathyroid gland [nTPM]":"26.9","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"3.1","Tissue RNA - pons [nTPM]":"0.5","Tissue RNA - prostate [nTPM]":"5.4","Tissue RNA - rectum [nTPM]":"4.0","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"1.2","Tissue RNA - seminal vesicle [nTPM]":"6.4","Tissue RNA - skeletal muscle [nTPM]":"2.3","Tissue RNA - skin 1 [nTPM]":"2.3","Tissue RNA - small intestine [nTPM]":"1.7","Tissue RNA - smooth muscle [nTPM]":"7.7","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"3.2","Tissue RNA - stomach 1 [nTPM]":"6.4","Tissue RNA - testis [nTPM]":"1.5","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"2.5","Tissue RNA - thyroid gland [nTPM]":"1.4","Tissue RNA - tongue [nTPM]":"1.6","Tissue RNA - tonsil [nTPM]":"1.1","Tissue RNA - urinary bladder [nTPM]":"4.2","Tissue RNA - vagina [nTPM]":"2.3","Tissue RNA - white matter [nTPM]":"1.1","Cell RNA - A-431 [nTPM]":"15.5","Cell RNA - A549 [nTPM]":"12.2","Cell RNA - AF22 [nTPM]":"5.9","Cell RNA - AN3-CA [nTPM]":"0.8","Cell RNA - ASC diff [nTPM]":"40.5","Cell RNA - ASC TERT1 [nTPM]":"50.3","Cell RNA - BEWO [nTPM]":"4.0","Cell RNA - BJ [nTPM]":"2.9","Cell RNA - BJ hTERT+ [nTPM]":"8.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.3","Cell RNA - CACO-2 [nTPM]":"36.8","Cell RNA - CAPAN-2 [nTPM]":"4.9","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"6.6","Cell RNA - fHDF\/TERT166 [nTPM]":"7.2","Cell RNA - GAMG [nTPM]":"2.9","Cell RNA - HaCaT [nTPM]":"3.2","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"2.9","Cell RNA - HBF TERT88 [nTPM]":"1.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"3.7","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"1.6","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"38.3","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"41.6","Cell RNA - hTCEpi [nTPM]":"10.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.7","Cell RNA - hTERT-HME1 [nTPM]":"25.2","Cell RNA - hTERT-RPE1 [nTPM]":"8.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.7","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"11.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"43.0","Cell RNA - OE19 [nTPM]":"11.3","Cell RNA - PC-3 [nTPM]":"6.1","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"9.8","Cell RNA - RPTEC TERT1 [nTPM]":"8.7","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"3.4","Cell RNA - SH-SY5Y [nTPM]":"13.6","Cell RNA - SiHa [nTPM]":"0.8","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"6.4","Cell RNA - SuSa [nTPM]":"19.9","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"8.4","Cell RNA - U-138 MG [nTPM]":"3.3","Cell RNA - U-2 OS [nTPM]":"5.7","Cell RNA - U-2197 [nTPM]":"23.0","Cell RNA - U-251 MG [nTPM]":"6.2","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.6","Brain RNA - basal ganglia [nTPM]":"1.4","Brain RNA - cerebellum [nTPM]":"3.0","Brain RNA - cerebral cortex [nTPM]":"0.8","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"0.7","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"0.5","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"1.1","Single Cell Type RNA - Adipocytes [nTPM]":"1.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.5","Single Cell Type RNA - Astrocytes [nTPM]":"81.0","Single Cell Type RNA - B-cells [nTPM]":"1.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"29.0","Single Cell Type RNA - Bipolar cells [nTPM]":"4.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.6","Single Cell Type RNA - Early spermatids [nTPM]":"9.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.2","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.5","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.0","Single Cell Type RNA - Fibroblasts [nTPM]":"14.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"69.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.2","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"4.9","Single Cell Type RNA - Late spermatids [nTPM]":"8.1","Single Cell Type RNA - Leydig cells [nTPM]":"27.7","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"36.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"5.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"109.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.8","Single Cell Type RNA - Peritubular cells [nTPM]":"14.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.5","Single Cell Type RNA - Spermatocytes [nTPM]":"1.4","Single Cell Type RNA - Spermatogonia [nTPM]":"1.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"ROR2","Gene synonym":["BDB","BDB1","NTRKR2"],"Ensembl":"ENSG00000169071","Gene description":"Receptor tyrosine kinase like orphan receptor 2","Uniprot":["Q01974"],"Chromosome":"9","Position":"91563091-91950228","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Developmental protein","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"18.4","Endometrial stromal cells":"19.3","Fibroblasts":"14.4","Inhibitory neurons":"18.6","Microglial cells":"15.9","Oligodendrocyte precursor cells":"27.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"MAIT T-cell":"1.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"T-cells":"1.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"24.5","HHSteC":"63.1","HSkMC":"52.2","U-266\/70":"38.3","U-266\/84":"27.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"7","RNA pig brain regional specific nTPM":{"cerebellum":"7.2","spinal cord":"3.7"},"Antibody":["HPA021868"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA021868":"AB_1856406"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.48e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.86e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.28e-8"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.9","Tissue RNA - adrenal gland [nTPM]":"5.7","Tissue RNA - amygdala [nTPM]":"0.8","Tissue RNA - appendix [nTPM]":"3.9","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"4.4","Tissue RNA - cerebellum [nTPM]":"0.4","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"18.7","Tissue RNA - choroid plexus [nTPM]":"28.2","Tissue RNA - colon [nTPM]":"32.7","Tissue RNA - duodenum [nTPM]":"2.2","Tissue RNA - endometrium 1 [nTPM]":"23.7","Tissue RNA - epididymis [nTPM]":"1.5","Tissue RNA - esophagus [nTPM]":"8.2","Tissue RNA - fallopian tube [nTPM]":"11.6","Tissue RNA - gallbladder [nTPM]":"8.6","Tissue RNA - heart muscle [nTPM]":"11.1","Tissue RNA - hippocampal formation [nTPM]":"1.4","Tissue RNA - hypothalamus [nTPM]":"0.8","Tissue RNA - kidney [nTPM]":"1.4","Tissue RNA - liver [nTPM]":"0.5","Tissue RNA - lung [nTPM]":"5.5","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"1.7","Tissue RNA - midbrain [nTPM]":"2.1","Tissue RNA - ovary [nTPM]":"13.9","Tissue RNA - pancreas [nTPM]":"1.6","Tissue RNA - parathyroid gland [nTPM]":"16.6","Tissue RNA - pituitary gland [nTPM]":"1.6","Tissue RNA - placenta [nTPM]":"3.5","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"13.9","Tissue RNA - rectum [nTPM]":"2.2","Tissue RNA - retina [nTPM]":"1.0","Tissue RNA - salivary gland [nTPM]":"1.6","Tissue RNA - seminal vesicle [nTPM]":"13.3","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"4.2","Tissue RNA - small intestine [nTPM]":"7.7","Tissue RNA - smooth muscle [nTPM]":"11.0","Tissue RNA - spinal cord [nTPM]":"1.2","Tissue RNA - spleen [nTPM]":"3.3","Tissue RNA - stomach 1 [nTPM]":"12.8","Tissue RNA - testis [nTPM]":"3.4","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"3.0","Tissue RNA - thyroid gland [nTPM]":"5.6","Tissue RNA - tongue [nTPM]":"0.7","Tissue RNA - tonsil [nTPM]":"1.0","Tissue RNA - urinary bladder [nTPM]":"17.5","Tissue RNA - vagina [nTPM]":"10.6","Tissue RNA - white matter [nTPM]":"0.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"24.5","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"5.3","Cell RNA - ASC TERT1 [nTPM]":"0.5","Cell RNA - BEWO [nTPM]":"6.8","Cell RNA - BJ [nTPM]":"0.4","Cell RNA - BJ hTERT+ [nTPM]":"6.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.8","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.8","Cell RNA - GAMG [nTPM]":"3.9","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"5.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"1.7","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"4.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"18.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"63.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"52.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.6","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"14.7","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"3.6","Cell RNA - NTERA-2 [nTPM]":"3.8","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.0","Cell RNA - SH-SY5Y [nTPM]":"7.2","Cell RNA - SiHa [nTPM]":"0.6","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"5.0","Cell RNA - T-47d [nTPM]":"14.8","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"4.8","Cell RNA - U-2197 [nTPM]":"2.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"38.3","Cell RNA - U-266\/84 [nTPM]":"27.5","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.8","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"0.4","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"1.4","Brain RNA - hypothalamus [nTPM]":"0.8","Brain RNA - medulla oblongata [nTPM]":"1.7","Brain RNA - midbrain [nTPM]":"2.1","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"1.2","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"0.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"1.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.5","Single Cell Type RNA - Early spermatids [nTPM]":"4.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.3","Single Cell Type RNA - Endothelial cells [nTPM]":"1.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"14.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"4.8","Single Cell Type RNA - Late spermatids [nTPM]":"8.6","Single Cell Type RNA - Leydig cells [nTPM]":"5.9","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"1.6","Single Cell Type RNA - Muller glia cells [nTPM]":"7.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"27.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"1.6","Single Cell Type RNA - Peritubular cells [nTPM]":"9.1","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.9","Single Cell Type RNA - Spermatocytes [nTPM]":"2.3","Single Cell Type RNA - Spermatogonia [nTPM]":"14.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"0.7","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.8","Single Cell Type RNA - Urothelial cells [nTPM]":"5.3"},{"Gene":"RPIA","Gene synonym":[],"Ensembl":"ENSG00000153574","Gene description":"Ribose 5-phosphate isomerase A","Uniprot":["P49247"],"Chromosome":"2","Position":"88691673-88750929","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Isomerase"],"Disease involvement":["Disease variant","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"89.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"234.3","Erythroid cells":"167.9","Syncytiotrophoblasts":"225.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042620","HPA057954"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2500000","Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Nucleoplasm","Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA042620":"AB_10793980","HPA057954":"AB_2683563"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.46e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.53e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.79e-3"},"Tissue RNA - adipose tissue [nTPM]":"17.2","Tissue RNA - adrenal gland [nTPM]":"11.0","Tissue RNA - amygdala [nTPM]":"7.4","Tissue RNA - appendix [nTPM]":"19.6","Tissue RNA - basal ganglia [nTPM]":"7.6","Tissue RNA - bone marrow [nTPM]":"89.6","Tissue RNA - breast [nTPM]":"16.0","Tissue RNA - cerebellum [nTPM]":"8.3","Tissue RNA - cerebral cortex [nTPM]":"8.9","Tissue RNA - cervix [nTPM]":"13.4","Tissue RNA - choroid plexus [nTPM]":"8.0","Tissue RNA - colon [nTPM]":"22.7","Tissue RNA - duodenum [nTPM]":"22.1","Tissue RNA - endometrium 1 [nTPM]":"13.2","Tissue RNA - epididymis [nTPM]":"9.5","Tissue RNA - esophagus [nTPM]":"24.1","Tissue RNA - fallopian tube [nTPM]":"14.6","Tissue RNA - gallbladder [nTPM]":"11.7","Tissue RNA - heart muscle [nTPM]":"16.0","Tissue RNA - hippocampal formation [nTPM]":"7.3","Tissue RNA - hypothalamus [nTPM]":"8.2","Tissue RNA - kidney [nTPM]":"10.6","Tissue RNA - liver [nTPM]":"7.8","Tissue RNA - lung [nTPM]":"12.2","Tissue RNA - lymph node [nTPM]":"28.0","Tissue RNA - medulla oblongata [nTPM]":"7.8","Tissue RNA - midbrain [nTPM]":"7.5","Tissue RNA - ovary [nTPM]":"13.7","Tissue RNA - pancreas [nTPM]":"17.9","Tissue RNA - parathyroid gland [nTPM]":"7.4","Tissue RNA - pituitary gland [nTPM]":"8.2","Tissue RNA - placenta [nTPM]":"33.8","Tissue RNA - pons [nTPM]":"7.5","Tissue RNA - prostate [nTPM]":"8.9","Tissue RNA - rectum [nTPM]":"23.0","Tissue RNA - retina [nTPM]":"4.1","Tissue RNA - salivary gland [nTPM]":"15.9","Tissue RNA - seminal vesicle [nTPM]":"8.1","Tissue RNA - skeletal muscle [nTPM]":"29.9","Tissue RNA - skin 1 [nTPM]":"11.9","Tissue RNA - small intestine [nTPM]":"18.9","Tissue RNA - smooth muscle [nTPM]":"12.5","Tissue RNA - spinal cord [nTPM]":"7.8","Tissue RNA - spleen [nTPM]":"19.2","Tissue RNA - stomach 1 [nTPM]":"18.9","Tissue RNA - testis [nTPM]":"9.6","Tissue RNA - thalamus [nTPM]":"8.0","Tissue RNA - thymus [nTPM]":"40.4","Tissue RNA - thyroid gland [nTPM]":"9.7","Tissue RNA - tongue [nTPM]":"17.1","Tissue RNA - tonsil [nTPM]":"32.4","Tissue RNA - urinary bladder [nTPM]":"16.5","Tissue RNA - vagina [nTPM]":"12.5","Tissue RNA - white matter [nTPM]":"7.9","Cell RNA - A-431 [nTPM]":"29.7","Cell RNA - A549 [nTPM]":"17.0","Cell RNA - AF22 [nTPM]":"33.7","Cell RNA - AN3-CA [nTPM]":"26.9","Cell RNA - ASC diff [nTPM]":"23.4","Cell RNA - ASC TERT1 [nTPM]":"23.9","Cell RNA - BEWO [nTPM]":"73.8","Cell RNA - BJ [nTPM]":"16.1","Cell RNA - BJ hTERT+ [nTPM]":"15.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"26.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.8","Cell RNA - CACO-2 [nTPM]":"61.1","Cell RNA - CAPAN-2 [nTPM]":"38.2","Cell RNA - Daudi [nTPM]":"150.1","Cell RNA - EFO-21 [nTPM]":"34.3","Cell RNA - fHDF\/TERT166 [nTPM]":"18.7","Cell RNA - GAMG [nTPM]":"35.8","Cell RNA - HaCaT [nTPM]":"17.7","Cell RNA - HAP1 [nTPM]":"42.4","Cell RNA - HBEC3-KT [nTPM]":"13.5","Cell RNA - HBF TERT88 [nTPM]":"40.9","Cell RNA - HDLM-2 [nTPM]":"71.9","Cell RNA - HEK 293 [nTPM]":"55.3","Cell RNA - HEL [nTPM]":"60.2","Cell RNA - HeLa [nTPM]":"11.0","Cell RNA - Hep G2 [nTPM]":"60.7","Cell RNA - HHSteC [nTPM]":"23.7","Cell RNA - HL-60 [nTPM]":"111.5","Cell RNA - HMC-1 [nTPM]":"42.4","Cell RNA - HSkMC [nTPM]":"22.1","Cell RNA - hTCEpi [nTPM]":"11.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"23.3","Cell RNA - hTERT-HME1 [nTPM]":"35.9","Cell RNA - hTERT-RPE1 [nTPM]":"13.0","Cell RNA - HUVEC TERT2 [nTPM]":"37.4","Cell RNA - JURKAT [nTPM]":"78.7","Cell RNA - K-562 [nTPM]":"65.7","Cell RNA - Karpas-707 [nTPM]":"25.3","Cell RNA - LHCN-M2 [nTPM]":"24.8","Cell RNA - MCF7 [nTPM]":"46.5","Cell RNA - MOLT-4 [nTPM]":"123.4","Cell RNA - NB-4 [nTPM]":"97.2","Cell RNA - NTERA-2 [nTPM]":"30.7","Cell RNA - OE19 [nTPM]":"97.6","Cell RNA - PC-3 [nTPM]":"27.7","Cell RNA - REH [nTPM]":"63.5","Cell RNA - RH-30 [nTPM]":"40.1","Cell RNA - RPMI-8226 [nTPM]":"36.8","Cell RNA - RPTEC TERT1 [nTPM]":"21.7","Cell RNA - RT4 [nTPM]":"47.1","Cell RNA - SCLC-21H [nTPM]":"24.0","Cell RNA - SH-SY5Y [nTPM]":"27.4","Cell RNA - SiHa [nTPM]":"19.4","Cell RNA - SK-BR-3 [nTPM]":"24.8","Cell RNA - SK-MEL-30 [nTPM]":"39.3","Cell RNA - SuSa [nTPM]":"18.3","Cell RNA - T-47d [nTPM]":"13.5","Cell RNA - THP-1 [nTPM]":"45.3","Cell RNA - TIME [nTPM]":"21.4","Cell RNA - U-138 MG [nTPM]":"15.5","Cell RNA - U-2 OS [nTPM]":"40.7","Cell RNA - U-2197 [nTPM]":"51.2","Cell RNA - U-251 MG [nTPM]":"46.7","Cell RNA - U-266\/70 [nTPM]":"19.7","Cell RNA - U-266\/84 [nTPM]":"17.2","Cell RNA - U-698 [nTPM]":"149.3","Cell RNA - U-87 MG [nTPM]":"15.9","Cell RNA - U-937 [nTPM]":"99.4","Cell RNA - WM-115 [nTPM]":"22.5","Blood RNA - basophil [nTPM]":"10.6","Blood RNA - classical monocyte [nTPM]":"16.0","Blood RNA - eosinophil [nTPM]":"36.4","Blood RNA - gdT-cell [nTPM]":"16.9","Blood RNA - intermediate monocyte [nTPM]":"16.7","Blood RNA - MAIT T-cell [nTPM]":"21.4","Blood RNA - memory B-cell [nTPM]":"31.4","Blood RNA - memory CD4 T-cell [nTPM]":"23.5","Blood RNA - memory CD8 T-cell [nTPM]":"25.1","Blood RNA - myeloid DC [nTPM]":"22.7","Blood RNA - naive B-cell [nTPM]":"23.5","Blood RNA - naive CD4 T-cell [nTPM]":"33.4","Blood RNA - naive CD8 T-cell [nTPM]":"27.8","Blood RNA - neutrophil [nTPM]":"3.9","Blood RNA - NK-cell [nTPM]":"21.9","Blood RNA - non-classical monocyte [nTPM]":"21.9","Blood RNA - plasmacytoid DC [nTPM]":"10.9","Blood RNA - T-reg [nTPM]":"22.0","Blood RNA - total PBMC [nTPM]":"20.6","Brain RNA - amygdala [nTPM]":"7.4","Brain RNA - basal ganglia [nTPM]":"7.6","Brain RNA - cerebellum [nTPM]":"8.3","Brain RNA - cerebral cortex [nTPM]":"8.9","Brain RNA - hippocampal formation [nTPM]":"7.3","Brain RNA - hypothalamus [nTPM]":"8.2","Brain RNA - medulla oblongata [nTPM]":"7.8","Brain RNA - midbrain [nTPM]":"7.5","Brain RNA - pons [nTPM]":"7.5","Brain RNA - spinal cord [nTPM]":"7.8","Brain RNA - thalamus [nTPM]":"8.0","Brain RNA - white matter [nTPM]":"7.9","Single Cell Type RNA - Adipocytes [nTPM]":"38.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.2","Single Cell Type RNA - Astrocytes [nTPM]":"4.6","Single Cell Type RNA - B-cells [nTPM]":"43.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"37.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"31.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.6","Single Cell Type RNA - Bipolar cells [nTPM]":"8.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"22.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"234.3","Single Cell Type RNA - dendritic cells [nTPM]":"37.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"20.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"21.7","Single Cell Type RNA - Early spermatids [nTPM]":"8.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"28.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.3","Single Cell Type RNA - Endothelial cells [nTPM]":"35.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.2","Single Cell Type RNA - Erythroid cells [nTPM]":"167.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"34.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"98.9","Single Cell Type RNA - Fibroblasts [nTPM]":"23.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"31.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"43.2","Single Cell Type RNA - granulocytes [nTPM]":"21.6","Single Cell Type RNA - Granulosa cells [nTPM]":"30.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"24.3","Single Cell Type RNA - Hepatocytes [nTPM]":"7.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"43.8","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.9","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"23.1","Single Cell Type RNA - Langerhans cells [nTPM]":"33.9","Single Cell Type RNA - Late spermatids [nTPM]":"4.0","Single Cell Type RNA - Leydig cells [nTPM]":"19.9","Single Cell Type RNA - Macrophages [nTPM]":"23.7","Single Cell Type RNA - Melanocytes [nTPM]":"40.9","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"32.4","Single Cell Type RNA - Muller glia cells [nTPM]":"5.2","Single Cell Type RNA - NK-cells [nTPM]":"60.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"13.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.8","Single Cell Type RNA - Paneth cells [nTPM]":"28.1","Single Cell Type RNA - Peritubular cells [nTPM]":"18.8","Single Cell Type RNA - Plasma cells [nTPM]":"35.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"41.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.8","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.0","Single Cell Type RNA - Spermatocytes [nTPM]":"28.4","Single Cell Type RNA - Spermatogonia [nTPM]":"33.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"37.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"40.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"225.6","Single Cell Type RNA - T-cells [nTPM]":"38.8","Single Cell Type RNA - Theca cells [nTPM]":"37.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"58.5","Single Cell Type RNA - Urothelial cells [nTPM]":"43.7"},{"Gene":"RPS6KA3","Gene synonym":["CLS","HU-3","MRX19","RSK2"],"Ensembl":"ENSG00000177189","Gene description":"Ribosomal protein S6 kinase A3","Uniprot":["P51812"],"Chromosome":"X","Position":"20149911-20267519","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell cycle","Stress response"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"236.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003221","CAB003853","CAB013520"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli","Cytosol"],"Antibody RRID":{"CAB003853":"AB_562343","CAB013520":"AB_2533378","HPA003221":"AB_1853553"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Tissue RNA - adipose tissue [nTPM]":"21.1","Tissue RNA - adrenal gland [nTPM]":"18.8","Tissue RNA - amygdala [nTPM]":"6.9","Tissue RNA - appendix [nTPM]":"33.7","Tissue RNA - basal ganglia [nTPM]":"10.2","Tissue RNA - bone marrow [nTPM]":"16.2","Tissue RNA - breast [nTPM]":"14.8","Tissue RNA - cerebellum [nTPM]":"12.7","Tissue RNA - cerebral cortex [nTPM]":"12.8","Tissue RNA - cervix [nTPM]":"16.1","Tissue RNA - choroid plexus [nTPM]":"8.5","Tissue RNA - colon [nTPM]":"32.8","Tissue RNA - duodenum [nTPM]":"24.1","Tissue RNA - endometrium 1 [nTPM]":"17.5","Tissue RNA - epididymis [nTPM]":"8.5","Tissue RNA - esophagus [nTPM]":"18.7","Tissue RNA - fallopian tube [nTPM]":"15.1","Tissue RNA - gallbladder [nTPM]":"26.9","Tissue RNA - heart muscle [nTPM]":"21.1","Tissue RNA - hippocampal formation [nTPM]":"8.7","Tissue RNA - hypothalamus [nTPM]":"9.4","Tissue RNA - kidney [nTPM]":"19.5","Tissue RNA - liver [nTPM]":"45.0","Tissue RNA - lung [nTPM]":"32.3","Tissue RNA - lymph node [nTPM]":"31.3","Tissue RNA - medulla oblongata [nTPM]":"8.4","Tissue RNA - midbrain [nTPM]":"10.0","Tissue RNA - ovary [nTPM]":"10.6","Tissue RNA - pancreas [nTPM]":"17.2","Tissue RNA - parathyroid gland [nTPM]":"59.4","Tissue RNA - pituitary gland [nTPM]":"5.9","Tissue RNA - placenta [nTPM]":"19.5","Tissue RNA - pons [nTPM]":"8.5","Tissue RNA - prostate [nTPM]":"19.9","Tissue RNA - rectum [nTPM]":"31.8","Tissue RNA - retina [nTPM]":"15.7","Tissue RNA - salivary gland [nTPM]":"13.2","Tissue RNA - seminal vesicle [nTPM]":"18.0","Tissue RNA - skeletal muscle [nTPM]":"51.8","Tissue RNA - skin 1 [nTPM]":"15.0","Tissue RNA - small intestine [nTPM]":"27.6","Tissue RNA - smooth muscle [nTPM]":"27.8","Tissue RNA - spinal cord [nTPM]":"8.7","Tissue RNA - spleen [nTPM]":"29.2","Tissue RNA - stomach 1 [nTPM]":"21.1","Tissue RNA - testis [nTPM]":"5.5","Tissue RNA - thalamus [nTPM]":"10.6","Tissue RNA - thymus [nTPM]":"32.9","Tissue RNA - thyroid gland [nTPM]":"21.2","Tissue RNA - tongue [nTPM]":"40.3","Tissue RNA - tonsil [nTPM]":"32.6","Tissue RNA - urinary bladder [nTPM]":"34.2","Tissue RNA - vagina [nTPM]":"8.5","Tissue RNA - white matter [nTPM]":"8.0","Cell RNA - A-431 [nTPM]":"44.9","Cell RNA - A549 [nTPM]":"77.0","Cell RNA - AF22 [nTPM]":"28.4","Cell RNA - AN3-CA [nTPM]":"14.8","Cell RNA - ASC diff [nTPM]":"27.1","Cell RNA - ASC TERT1 [nTPM]":"47.3","Cell RNA - BEWO [nTPM]":"8.6","Cell RNA - BJ [nTPM]":"38.0","Cell RNA - BJ hTERT+ [nTPM]":"57.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"27.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"37.7","Cell RNA - CACO-2 [nTPM]":"87.7","Cell RNA - CAPAN-2 [nTPM]":"56.2","Cell RNA - Daudi [nTPM]":"29.3","Cell RNA - EFO-21 [nTPM]":"12.8","Cell RNA - fHDF\/TERT166 [nTPM]":"40.0","Cell RNA - GAMG [nTPM]":"40.5","Cell RNA - HaCaT [nTPM]":"30.9","Cell RNA - HAP1 [nTPM]":"32.8","Cell RNA - HBEC3-KT [nTPM]":"32.2","Cell RNA - HBF TERT88 [nTPM]":"51.1","Cell RNA - HDLM-2 [nTPM]":"24.8","Cell RNA - HEK 293 [nTPM]":"26.1","Cell RNA - HEL [nTPM]":"34.6","Cell RNA - HeLa [nTPM]":"46.2","Cell RNA - Hep G2 [nTPM]":"236.8","Cell RNA - HHSteC [nTPM]":"27.7","Cell RNA - HL-60 [nTPM]":"67.8","Cell RNA - HMC-1 [nTPM]":"34.2","Cell RNA - HSkMC [nTPM]":"30.3","Cell RNA - hTCEpi [nTPM]":"25.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"43.5","Cell RNA - hTERT-HME1 [nTPM]":"54.4","Cell RNA - hTERT-RPE1 [nTPM]":"24.3","Cell RNA - HUVEC TERT2 [nTPM]":"101.9","Cell RNA - JURKAT [nTPM]":"30.4","Cell RNA - K-562 [nTPM]":"23.1","Cell RNA - Karpas-707 [nTPM]":"81.0","Cell RNA - LHCN-M2 [nTPM]":"29.4","Cell RNA - MCF7 [nTPM]":"21.2","Cell RNA - MOLT-4 [nTPM]":"44.2","Cell RNA - NB-4 [nTPM]":"20.7","Cell RNA - NTERA-2 [nTPM]":"20.6","Cell RNA - OE19 [nTPM]":"57.8","Cell RNA - PC-3 [nTPM]":"45.9","Cell RNA - REH [nTPM]":"23.3","Cell RNA - RH-30 [nTPM]":"60.0","Cell RNA - RPMI-8226 [nTPM]":"33.8","Cell RNA - RPTEC TERT1 [nTPM]":"23.9","Cell RNA - RT4 [nTPM]":"36.9","Cell RNA - SCLC-21H [nTPM]":"13.1","Cell RNA - SH-SY5Y [nTPM]":"12.8","Cell RNA - SiHa [nTPM]":"51.1","Cell RNA - SK-BR-3 [nTPM]":"15.3","Cell RNA - SK-MEL-30 [nTPM]":"54.4","Cell RNA - SuSa [nTPM]":"35.3","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"20.0","Cell RNA - TIME [nTPM]":"57.3","Cell RNA - U-138 MG [nTPM]":"30.1","Cell RNA - U-2 OS [nTPM]":"20.8","Cell RNA - U-2197 [nTPM]":"96.3","Cell RNA - U-251 MG [nTPM]":"21.7","Cell RNA - U-266\/70 [nTPM]":"64.3","Cell RNA - U-266\/84 [nTPM]":"42.1","Cell RNA - U-698 [nTPM]":"32.1","Cell RNA - U-87 MG [nTPM]":"56.9","Cell RNA - U-937 [nTPM]":"33.1","Cell RNA - WM-115 [nTPM]":"72.6","Blood RNA - basophil [nTPM]":"11.9","Blood RNA - classical monocyte [nTPM]":"3.8","Blood RNA - eosinophil [nTPM]":"7.9","Blood RNA - gdT-cell [nTPM]":"4.7","Blood RNA - intermediate monocyte [nTPM]":"5.3","Blood RNA - MAIT T-cell [nTPM]":"8.3","Blood RNA - memory B-cell [nTPM]":"2.4","Blood RNA - memory CD4 T-cell [nTPM]":"5.4","Blood RNA - memory CD8 T-cell [nTPM]":"5.2","Blood RNA - myeloid DC [nTPM]":"5.6","Blood RNA - naive B-cell [nTPM]":"3.2","Blood RNA - naive CD4 T-cell [nTPM]":"3.7","Blood RNA - naive CD8 T-cell [nTPM]":"4.5","Blood RNA - neutrophil [nTPM]":"5.8","Blood RNA - NK-cell [nTPM]":"6.6","Blood RNA - non-classical monocyte [nTPM]":"6.0","Blood RNA - plasmacytoid DC [nTPM]":"6.7","Blood RNA - T-reg [nTPM]":"2.9","Blood RNA - total PBMC [nTPM]":"2.2","Brain RNA - amygdala [nTPM]":"6.9","Brain RNA - basal ganglia [nTPM]":"10.2","Brain RNA - cerebellum [nTPM]":"12.7","Brain RNA - cerebral cortex [nTPM]":"12.8","Brain RNA - hippocampal formation [nTPM]":"8.7","Brain RNA - hypothalamus [nTPM]":"9.4","Brain RNA - medulla oblongata [nTPM]":"8.4","Brain RNA - midbrain [nTPM]":"10.0","Brain RNA - pons [nTPM]":"8.5","Brain RNA - spinal cord [nTPM]":"8.7","Brain RNA - thalamus [nTPM]":"10.6","Brain RNA - white matter [nTPM]":"8.0","Single Cell Type RNA - Adipocytes [nTPM]":"60.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"67.5","Single Cell Type RNA - Astrocytes [nTPM]":"31.6","Single Cell Type RNA - B-cells [nTPM]":"34.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"54.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"37.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"37.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"20.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"22.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"34.3","Single Cell Type RNA - Club cells [nTPM]":"41.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.0","Single Cell Type RNA - dendritic cells [nTPM]":"70.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"63.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"26.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"24.0","Single Cell Type RNA - Endothelial cells [nTPM]":"61.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"25.0","Single Cell Type RNA - Erythroid cells [nTPM]":"19.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"142.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.7","Single Cell Type RNA - Fibroblasts [nTPM]":"31.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"24.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.1","Single Cell Type RNA - granulocytes [nTPM]":"44.3","Single Cell Type RNA - Granulosa cells [nTPM]":"8.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"34.6","Single Cell Type RNA - Hepatocytes [nTPM]":"65.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.6","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"108.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"59.1","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"40.8","Single Cell Type RNA - Langerhans cells [nTPM]":"104.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"13.1","Single Cell Type RNA - Macrophages [nTPM]":"62.6","Single Cell Type RNA - Melanocytes [nTPM]":"37.4","Single Cell Type RNA - Microglial cells [nTPM]":"126.5","Single Cell Type RNA - monocytes [nTPM]":"53.7","Single Cell Type RNA - Muller glia cells [nTPM]":"27.5","Single Cell Type RNA - NK-cells [nTPM]":"46.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"116.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"27.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"37.4","Single Cell Type RNA - Paneth cells [nTPM]":"57.9","Single Cell Type RNA - Peritubular cells [nTPM]":"21.1","Single Cell Type RNA - Plasma cells [nTPM]":"25.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"56.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"33.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"25.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.7","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"41.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.3","Single Cell Type RNA - Spermatocytes [nTPM]":"6.4","Single Cell Type RNA - Spermatogonia [nTPM]":"8.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"55.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.6","Single Cell Type RNA - T-cells [nTPM]":"66.0","Single Cell Type RNA - Theca cells [nTPM]":"14.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"61.1","Single Cell Type RNA - Urothelial cells [nTPM]":"63.8"},{"Gene":"RS1","Gene synonym":["RS","XLRS1"],"Ensembl":"ENSG00000102104","Gene description":"Retinoschisin 1","Uniprot":["O15537"],"Chromosome":"X","Position":"18639688-18672108","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted secreted proteins","Transporters"],"Biological process":["Cell adhesion","Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"207","RNA tissue specific nTPM":{"retina":"213.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"160.6","Rod photoreceptor cells":"162.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059546"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA059546":"AB_2684058"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.03e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-4"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"213.7","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"15.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"160.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"26.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"162.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.2","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"RTEL1","Gene synonym":["bK3184A7.3","C20orf41","DKFZP434C013","KIAA1088","NHL","RTEL"],"Ensembl":"ENSG00000258366","Gene description":"Regulator of telomere elongation helicase 1","Uniprot":["Q9NZ71"],"Chromosome":"20","Position":"63657810-63696253","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Disease variant","Dyskeratosis congenita"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"1.0","Erythroid cells":"3.8","Gastric mucus-secreting cells":"3.1","Plasma cells":"3.0","Squamous epithelial cells":"1.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020622","HPA067329","HPA078328"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Nuclear speckles","Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA020622":"AB_2732425","HPA067329":"AB_2685823","HPA078328":"AB_2732380"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.77e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.9","Tissue RNA - adrenal gland [nTPM]":"7.0","Tissue RNA - amygdala [nTPM]":"1.3","Tissue RNA - appendix [nTPM]":"6.1","Tissue RNA - basal ganglia [nTPM]":"1.6","Tissue RNA - bone marrow [nTPM]":"8.2","Tissue RNA - breast [nTPM]":"5.2","Tissue RNA - cerebellum [nTPM]":"5.7","Tissue RNA - cerebral cortex [nTPM]":"4.7","Tissue RNA - cervix [nTPM]":"6.8","Tissue RNA - choroid plexus [nTPM]":"0.5","Tissue RNA - colon [nTPM]":"8.5","Tissue RNA - duodenum [nTPM]":"4.8","Tissue RNA - endometrium 1 [nTPM]":"10.0","Tissue RNA - epididymis [nTPM]":"3.0","Tissue RNA - esophagus [nTPM]":"4.6","Tissue RNA - fallopian tube [nTPM]":"6.2","Tissue RNA - gallbladder [nTPM]":"3.0","Tissue RNA - heart muscle [nTPM]":"3.9","Tissue RNA - hippocampal formation [nTPM]":"1.2","Tissue RNA - hypothalamus [nTPM]":"0.9","Tissue RNA - kidney [nTPM]":"4.1","Tissue RNA - liver [nTPM]":"4.8","Tissue RNA - lung [nTPM]":"6.0","Tissue RNA - lymph node [nTPM]":"4.2","Tissue RNA - medulla oblongata [nTPM]":"2.9","Tissue RNA - midbrain [nTPM]":"0.6","Tissue RNA - ovary [nTPM]":"6.4","Tissue RNA - pancreas [nTPM]":"8.6","Tissue RNA - parathyroid gland [nTPM]":"2.8","Tissue RNA - pituitary gland [nTPM]":"12.2","Tissue RNA - placenta [nTPM]":"4.2","Tissue RNA - pons [nTPM]":"1.8","Tissue RNA - prostate [nTPM]":"6.7","Tissue RNA - rectum [nTPM]":"2.1","Tissue RNA - retina [nTPM]":"2.5","Tissue RNA - salivary gland [nTPM]":"6.3","Tissue RNA - seminal vesicle [nTPM]":"4.5","Tissue RNA - skeletal muscle [nTPM]":"5.4","Tissue RNA - skin 1 [nTPM]":"4.5","Tissue RNA - small intestine [nTPM]":"5.8","Tissue RNA - smooth muscle [nTPM]":"3.1","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"6.1","Tissue RNA - stomach 1 [nTPM]":"6.6","Tissue RNA - testis [nTPM]":"7.6","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"4.8","Tissue RNA - thyroid gland [nTPM]":"7.8","Tissue RNA - tongue [nTPM]":"2.3","Tissue RNA - tonsil [nTPM]":"2.4","Tissue RNA - urinary bladder [nTPM]":"6.5","Tissue RNA - vagina [nTPM]":"6.0","Tissue RNA - white matter [nTPM]":"1.5","Cell RNA - A-431 [nTPM]":"8.3","Cell RNA - A549 [nTPM]":"11.7","Cell RNA - AF22 [nTPM]":"7.9","Cell RNA - AN3-CA [nTPM]":"15.5","Cell RNA - ASC diff [nTPM]":"1.6","Cell RNA - ASC TERT1 [nTPM]":"1.7","Cell RNA - BEWO [nTPM]":"14.5","Cell RNA - BJ [nTPM]":"16.8","Cell RNA - BJ hTERT+ [nTPM]":"4.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"26.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.6","Cell RNA - CACO-2 [nTPM]":"22.2","Cell RNA - CAPAN-2 [nTPM]":"7.0","Cell RNA - Daudi [nTPM]":"11.0","Cell RNA - EFO-21 [nTPM]":"8.6","Cell RNA - fHDF\/TERT166 [nTPM]":"5.2","Cell RNA - GAMG [nTPM]":"9.8","Cell RNA - HaCaT [nTPM]":"15.3","Cell RNA - HAP1 [nTPM]":"5.5","Cell RNA - HBEC3-KT [nTPM]":"11.1","Cell RNA - HBF TERT88 [nTPM]":"6.1","Cell RNA - HDLM-2 [nTPM]":"5.5","Cell RNA - HEK 293 [nTPM]":"11.0","Cell RNA - HEL [nTPM]":"13.8","Cell RNA - HeLa [nTPM]":"21.2","Cell RNA - Hep G2 [nTPM]":"21.5","Cell RNA - HHSteC [nTPM]":"5.7","Cell RNA - HL-60 [nTPM]":"13.4","Cell RNA - HMC-1 [nTPM]":"24.1","Cell RNA - HSkMC [nTPM]":"2.2","Cell RNA - hTCEpi [nTPM]":"6.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.4","Cell RNA - hTERT-HME1 [nTPM]":"7.9","Cell RNA - hTERT-RPE1 [nTPM]":"4.9","Cell RNA - HUVEC TERT2 [nTPM]":"9.0","Cell RNA - JURKAT [nTPM]":"19.6","Cell RNA - K-562 [nTPM]":"17.4","Cell RNA - Karpas-707 [nTPM]":"10.4","Cell RNA - LHCN-M2 [nTPM]":"5.8","Cell RNA - MCF7 [nTPM]":"8.7","Cell RNA - MOLT-4 [nTPM]":"21.3","Cell RNA - NB-4 [nTPM]":"17.5","Cell RNA - NTERA-2 [nTPM]":"7.8","Cell RNA - OE19 [nTPM]":"7.1","Cell RNA - PC-3 [nTPM]":"22.3","Cell RNA - REH [nTPM]":"17.2","Cell RNA - RH-30 [nTPM]":"7.4","Cell RNA - RPMI-8226 [nTPM]":"11.6","Cell RNA - RPTEC TERT1 [nTPM]":"4.1","Cell RNA - RT4 [nTPM]":"9.7","Cell RNA - SCLC-21H [nTPM]":"15.7","Cell RNA - SH-SY5Y [nTPM]":"9.3","Cell RNA - SiHa [nTPM]":"9.3","Cell RNA - SK-BR-3 [nTPM]":"27.5","Cell RNA - SK-MEL-30 [nTPM]":"2.2","Cell RNA - SuSa [nTPM]":"3.6","Cell RNA - T-47d [nTPM]":"7.2","Cell RNA - THP-1 [nTPM]":"15.2","Cell RNA - TIME [nTPM]":"12.1","Cell RNA - U-138 MG [nTPM]":"29.4","Cell RNA - U-2 OS [nTPM]":"9.5","Cell RNA - U-2197 [nTPM]":"10.1","Cell RNA - U-251 MG [nTPM]":"13.2","Cell RNA - U-266\/70 [nTPM]":"9.4","Cell RNA - U-266\/84 [nTPM]":"4.2","Cell RNA - U-698 [nTPM]":"7.1","Cell RNA - U-87 MG [nTPM]":"7.1","Cell RNA - U-937 [nTPM]":"9.5","Cell RNA - WM-115 [nTPM]":"10.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.9","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"1.3","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.9","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"1.0","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"0.5","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"1.3","Brain RNA - basal ganglia [nTPM]":"1.6","Brain RNA - cerebellum [nTPM]":"5.7","Brain RNA - cerebral cortex [nTPM]":"4.7","Brain RNA - hippocampal formation [nTPM]":"1.2","Brain RNA - hypothalamus [nTPM]":"0.9","Brain RNA - medulla oblongata [nTPM]":"2.9","Brain RNA - midbrain [nTPM]":"0.6","Brain RNA - pons [nTPM]":"1.8","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"1.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"3.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.7","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"RXFP2","Gene synonym":["GPR106","GREAT","INSL3R","LGR8","RXFPR2"],"Ensembl":"ENSG00000133105","Gene description":"Relaxin family peptide receptor 2","Uniprot":["Q8WXD0"],"Chromosome":"13","Position":"31739526-31803389","Protein class":["Disease related genes","G-protein coupled receptors","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Early spermatids":"8.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"classical monocyte":"1.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"monocytes":"1.7"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"10","RNA pig brain regional specific nTPM":{"basal ganglia":"2.6"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 23: Spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.7","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.5","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.8","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.7","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.7","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"8.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"S1PR2","Gene synonym":["AGR16","DFNB68","EDG5","Gpcr13","H218"],"Ensembl":"ENSG00000267534","Gene description":"Sphingosine-1-phosphate receptor 2","Uniprot":["O95136"],"Chromosome":"19","Position":"10221433-10231331","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cytotrophoblasts":"92.9","Early spermatids":"92.3","Late spermatids":"184.9","Syncytiotrophoblasts":"68.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"45.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"45.0","T-cells":"12.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"29.4","Daudi":"54.1","U-266\/70":"38.9","U-698":"57.3","WM-115":"38.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014255","HPA014307"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nuclear speckles","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nuclear speckles"],"Antibody RRID":{"HPA014255":null,"HPA014307":"AB_1847989"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.36e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.7","Tissue RNA - adrenal gland [nTPM]":"2.5","Tissue RNA - amygdala [nTPM]":"1.9","Tissue RNA - appendix [nTPM]":"6.4","Tissue RNA - basal ganglia [nTPM]":"1.8","Tissue RNA - bone marrow [nTPM]":"1.2","Tissue RNA - breast [nTPM]":"5.5","Tissue RNA - cerebellum [nTPM]":"1.7","Tissue RNA - cerebral cortex [nTPM]":"1.8","Tissue RNA - cervix [nTPM]":"10.4","Tissue RNA - choroid plexus [nTPM]":"1.9","Tissue RNA - colon [nTPM]":"4.8","Tissue RNA - duodenum [nTPM]":"1.8","Tissue RNA - endometrium 1 [nTPM]":"8.3","Tissue RNA - epididymis [nTPM]":"2.7","Tissue RNA - esophagus [nTPM]":"3.3","Tissue RNA - fallopian tube [nTPM]":"8.4","Tissue RNA - gallbladder [nTPM]":"6.2","Tissue RNA - heart muscle [nTPM]":"6.6","Tissue RNA - hippocampal formation [nTPM]":"1.6","Tissue RNA - hypothalamus [nTPM]":"2.0","Tissue RNA - kidney [nTPM]":"3.1","Tissue RNA - liver [nTPM]":"5.6","Tissue RNA - lung [nTPM]":"13.7","Tissue RNA - lymph node [nTPM]":"10.9","Tissue RNA - medulla oblongata [nTPM]":"2.8","Tissue RNA - midbrain [nTPM]":"1.9","Tissue RNA - ovary [nTPM]":"5.6","Tissue RNA - pancreas [nTPM]":"2.9","Tissue RNA - parathyroid gland [nTPM]":"2.5","Tissue RNA - pituitary gland [nTPM]":"3.0","Tissue RNA - placenta [nTPM]":"18.5","Tissue RNA - pons [nTPM]":"2.2","Tissue RNA - prostate [nTPM]":"6.9","Tissue RNA - rectum [nTPM]":"2.4","Tissue RNA - retina [nTPM]":"1.2","Tissue RNA - salivary gland [nTPM]":"4.1","Tissue RNA - seminal vesicle [nTPM]":"2.3","Tissue RNA - skeletal muscle [nTPM]":"0.8","Tissue RNA - skin 1 [nTPM]":"5.4","Tissue RNA - small intestine [nTPM]":"4.8","Tissue RNA - smooth muscle [nTPM]":"4.2","Tissue RNA - spinal cord [nTPM]":"2.0","Tissue RNA - spleen [nTPM]":"1.9","Tissue RNA - stomach 1 [nTPM]":"4.3","Tissue RNA - testis [nTPM]":"13.2","Tissue RNA - thalamus [nTPM]":"2.1","Tissue RNA - thymus [nTPM]":"1.4","Tissue RNA - thyroid gland [nTPM]":"3.4","Tissue RNA - tongue [nTPM]":"1.3","Tissue RNA - tonsil [nTPM]":"10.9","Tissue RNA - urinary bladder [nTPM]":"8.3","Tissue RNA - vagina [nTPM]":"7.0","Tissue RNA - white matter [nTPM]":"2.9","Cell RNA - A-431 [nTPM]":"3.0","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"3.4","Cell RNA - AN3-CA [nTPM]":"6.9","Cell RNA - ASC diff [nTPM]":"18.2","Cell RNA - ASC TERT1 [nTPM]":"22.2","Cell RNA - BEWO [nTPM]":"29.4","Cell RNA - BJ [nTPM]":"4.4","Cell RNA - BJ hTERT+ [nTPM]":"8.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.1","Cell RNA - CACO-2 [nTPM]":"1.9","Cell RNA - CAPAN-2 [nTPM]":"1.7","Cell RNA - Daudi [nTPM]":"54.1","Cell RNA - EFO-21 [nTPM]":"5.1","Cell RNA - fHDF\/TERT166 [nTPM]":"8.2","Cell RNA - GAMG [nTPM]":"2.3","Cell RNA - HaCaT [nTPM]":"1.7","Cell RNA - HAP1 [nTPM]":"1.2","Cell RNA - HBEC3-KT [nTPM]":"2.1","Cell RNA - HBF TERT88 [nTPM]":"1.3","Cell RNA - HDLM-2 [nTPM]":"5.5","Cell RNA - HEK 293 [nTPM]":"2.7","Cell RNA - HEL [nTPM]":"1.2","Cell RNA - HeLa [nTPM]":"1.2","Cell RNA - Hep G2 [nTPM]":"1.3","Cell RNA - HHSteC [nTPM]":"6.1","Cell RNA - HL-60 [nTPM]":"1.4","Cell RNA - HMC-1 [nTPM]":"1.1","Cell RNA - HSkMC [nTPM]":"12.2","Cell RNA - hTCEpi [nTPM]":"1.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.8","Cell RNA - hTERT-HME1 [nTPM]":"1.3","Cell RNA - hTERT-RPE1 [nTPM]":"5.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"2.6","Cell RNA - K-562 [nTPM]":"1.3","Cell RNA - Karpas-707 [nTPM]":"11.1","Cell RNA - LHCN-M2 [nTPM]":"1.3","Cell RNA - MCF7 [nTPM]":"2.5","Cell RNA - MOLT-4 [nTPM]":"0.6","Cell RNA - NB-4 [nTPM]":"2.5","Cell RNA - NTERA-2 [nTPM]":"3.4","Cell RNA - OE19 [nTPM]":"0.9","Cell RNA - PC-3 [nTPM]":"1.7","Cell RNA - REH [nTPM]":"3.8","Cell RNA - RH-30 [nTPM]":"1.4","Cell RNA - RPMI-8226 [nTPM]":"2.0","Cell RNA - RPTEC TERT1 [nTPM]":"1.6","Cell RNA - RT4 [nTPM]":"2.5","Cell RNA - SCLC-21H [nTPM]":"2.4","Cell RNA - SH-SY5Y [nTPM]":"4.7","Cell RNA - SiHa [nTPM]":"2.5","Cell RNA - SK-BR-3 [nTPM]":"1.5","Cell RNA - SK-MEL-30 [nTPM]":"3.8","Cell RNA - SuSa [nTPM]":"2.6","Cell RNA - T-47d [nTPM]":"1.2","Cell RNA - THP-1 [nTPM]":"1.3","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"6.9","Cell RNA - U-2 OS [nTPM]":"2.2","Cell RNA - U-2197 [nTPM]":"15.9","Cell RNA - U-251 MG [nTPM]":"1.3","Cell RNA - U-266\/70 [nTPM]":"38.9","Cell RNA - U-266\/84 [nTPM]":"19.6","Cell RNA - U-698 [nTPM]":"57.3","Cell RNA - U-87 MG [nTPM]":"2.6","Cell RNA - U-937 [nTPM]":"2.7","Cell RNA - WM-115 [nTPM]":"38.6","Blood RNA - basophil [nTPM]":"45.0","Blood RNA - classical monocyte [nTPM]":"2.8","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"7.2","Blood RNA - intermediate monocyte [nTPM]":"2.4","Blood RNA - MAIT T-cell [nTPM]":"8.9","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"9.2","Blood RNA - memory CD8 T-cell [nTPM]":"7.0","Blood RNA - myeloid DC [nTPM]":"2.6","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"3.7","Blood RNA - naive CD8 T-cell [nTPM]":"3.8","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"3.6","Blood RNA - non-classical monocyte [nTPM]":"1.0","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"12.4","Blood RNA - total PBMC [nTPM]":"2.0","Brain RNA - amygdala [nTPM]":"1.9","Brain RNA - basal ganglia [nTPM]":"1.8","Brain RNA - cerebellum [nTPM]":"1.7","Brain RNA - cerebral cortex [nTPM]":"1.8","Brain RNA - hippocampal formation [nTPM]":"1.6","Brain RNA - hypothalamus [nTPM]":"2.0","Brain RNA - medulla oblongata [nTPM]":"2.8","Brain RNA - midbrain [nTPM]":"1.9","Brain RNA - pons [nTPM]":"2.2","Brain RNA - spinal cord [nTPM]":"2.0","Brain RNA - thalamus [nTPM]":"2.1","Brain RNA - white matter [nTPM]":"2.9","Single Cell Type RNA - Adipocytes [nTPM]":"2.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"2.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"92.9","Single Cell Type RNA - dendritic cells [nTPM]":"5.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.6","Single Cell Type RNA - Early spermatids [nTPM]":"92.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.5","Single Cell Type RNA - Endothelial cells [nTPM]":"2.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.1","Single Cell Type RNA - Fibroblasts [nTPM]":"17.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"7.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.1","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"184.9","Single Cell Type RNA - Leydig cells [nTPM]":"22.1","Single Cell Type RNA - Macrophages [nTPM]":"7.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"4.0","Single Cell Type RNA - Muller glia cells [nTPM]":"7.1","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"13.2","Single Cell Type RNA - Plasma cells [nTPM]":"2.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.6","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"68.4","Single Cell Type RNA - T-cells [nTPM]":"4.2","Single Cell Type RNA - Theca cells [nTPM]":"1.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"4.1"},{"Gene":"SARDH","Gene synonym":["DMGDHL1","SDH"],"Ensembl":"ENSG00000123453","Gene description":"Sarcosine dehydrogenase","Uniprot":["Q9UL12"],"Chromosome":"9","Position":"133663560-133739955","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"epididymis":"47.9","liver":"114.4","pancreas":"43.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Hepatocytes":"120.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"liver cancer":"18.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"memory CD4 T-cell":"3.3","naive CD4 T-cell":"6.7","T-reg":"8.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"16","RNA blood lineage specific nTPM":{"T-cells":"8.8"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AN3-CA":"17.4","Hep G2":"31.1","MOLT-4":"22.5","RH-30":"18.5","RPMI-8226":"39.1","SH-SY5Y":"14.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057267","HPA058086"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"230000","Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA057267":"AB_2683388","HPA058086":"AB_2683601"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.62e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.74e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.1","Tissue RNA - adrenal gland [nTPM]":"2.2","Tissue RNA - amygdala [nTPM]":"3.6","Tissue RNA - appendix [nTPM]":"2.5","Tissue RNA - basal ganglia [nTPM]":"3.5","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"0.8","Tissue RNA - cerebellum [nTPM]":"1.9","Tissue RNA - cerebral cortex [nTPM]":"3.9","Tissue RNA - cervix [nTPM]":"2.6","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"1.1","Tissue RNA - duodenum [nTPM]":"1.8","Tissue RNA - endometrium 1 [nTPM]":"2.0","Tissue RNA - epididymis [nTPM]":"47.9","Tissue RNA - esophagus [nTPM]":"0.6","Tissue RNA - fallopian tube [nTPM]":"1.9","Tissue RNA - gallbladder [nTPM]":"1.3","Tissue RNA - heart muscle [nTPM]":"2.4","Tissue RNA - hippocampal formation [nTPM]":"3.3","Tissue RNA - hypothalamus [nTPM]":"3.5","Tissue RNA - kidney [nTPM]":"12.0","Tissue RNA - liver [nTPM]":"114.4","Tissue RNA - lung [nTPM]":"2.6","Tissue RNA - lymph node [nTPM]":"4.1","Tissue RNA - medulla oblongata [nTPM]":"4.4","Tissue RNA - midbrain [nTPM]":"3.1","Tissue RNA - ovary [nTPM]":"3.0","Tissue RNA - pancreas [nTPM]":"43.2","Tissue RNA - parathyroid gland [nTPM]":"2.1","Tissue RNA - pituitary gland [nTPM]":"4.1","Tissue RNA - placenta [nTPM]":"0.9","Tissue RNA - pons [nTPM]":"3.4","Tissue RNA - prostate [nTPM]":"2.3","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"5.3","Tissue RNA - seminal vesicle [nTPM]":"1.8","Tissue RNA - skeletal muscle [nTPM]":"0.6","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"1.3","Tissue RNA - smooth muscle [nTPM]":"0.9","Tissue RNA - spinal cord [nTPM]":"2.9","Tissue RNA - spleen [nTPM]":"1.3","Tissue RNA - stomach 1 [nTPM]":"3.0","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"4.2","Tissue RNA - thymus [nTPM]":"4.3","Tissue RNA - thyroid gland [nTPM]":"1.6","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"2.4","Tissue RNA - urinary bladder [nTPM]":"1.1","Tissue RNA - vagina [nTPM]":"1.0","Tissue RNA - white matter [nTPM]":"3.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"1.4","Cell RNA - AN3-CA [nTPM]":"17.4","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.5","Cell RNA - BEWO [nTPM]":"2.3","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.1","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"2.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.3","Cell RNA - GAMG [nTPM]":"2.2","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"0.7","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"2.5","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"31.1","Cell RNA - HHSteC [nTPM]":"1.9","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"4.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"13.1","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"11.1","Cell RNA - MCF7 [nTPM]":"3.2","Cell RNA - MOLT-4 [nTPM]":"22.5","Cell RNA - NB-4 [nTPM]":"2.4","Cell RNA - NTERA-2 [nTPM]":"2.8","Cell RNA - OE19 [nTPM]":"1.7","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"1.6","Cell RNA - RH-30 [nTPM]":"18.5","Cell RNA - RPMI-8226 [nTPM]":"39.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"1.7","Cell RNA - SH-SY5Y [nTPM]":"14.7","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"3.9","Cell RNA - SuSa [nTPM]":"0.8","Cell RNA - T-47d [nTPM]":"2.4","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"3.3","Cell RNA - U-2 OS [nTPM]":"3.0","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"1.3","Cell RNA - U-87 MG [nTPM]":"2.1","Cell RNA - U-937 [nTPM]":"1.4","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"3.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"6.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.2","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"8.8","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"3.6","Brain RNA - basal ganglia [nTPM]":"3.5","Brain RNA - cerebellum [nTPM]":"1.9","Brain RNA - cerebral cortex [nTPM]":"3.9","Brain RNA - hippocampal formation [nTPM]":"3.3","Brain RNA - hypothalamus [nTPM]":"3.5","Brain RNA - medulla oblongata [nTPM]":"4.4","Brain RNA - midbrain [nTPM]":"3.1","Brain RNA - pons [nTPM]":"3.4","Brain RNA - spinal cord [nTPM]":"2.9","Brain RNA - thalamus [nTPM]":"4.2","Brain RNA - white matter [nTPM]":"3.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.9","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"5.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"2.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.9","Single Cell Type RNA - Hepatocytes [nTPM]":"120.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"4.7","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.2","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"21.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"4.2","Single Cell Type RNA - Theca cells [nTPM]":"1.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"SARS1","Gene synonym":["SARS","SERS"],"Ensembl":"ENSG00000031698","Gene description":"Seryl-tRNA synthetase 1","Uniprot":["P49591"],"Chromosome":"1","Position":"109213918-109238182","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis","Transcription","Transcription regulation"],"Molecular function":["Aminoacyl-tRNA synthetase","DNA-binding","Ligase"],"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cardiomyocytes":"98.8","Cytotrophoblasts":"186.0","Extravillous trophoblasts":"147.6","Hofbauer cells":"88.1","Syncytiotrophoblasts":"188.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016939","HPA064668"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"330000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA016939":"AB_1856585","HPA064668":"AB_2685316"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.47e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.75e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.13e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-3"},"Tissue RNA - adipose tissue [nTPM]":"86.9","Tissue RNA - adrenal gland [nTPM]":"89.4","Tissue RNA - amygdala [nTPM]":"78.6","Tissue RNA - appendix [nTPM]":"55.9","Tissue RNA - basal ganglia [nTPM]":"78.6","Tissue RNA - bone marrow [nTPM]":"35.7","Tissue RNA - breast [nTPM]":"80.5","Tissue RNA - cerebellum [nTPM]":"77.2","Tissue RNA - cerebral cortex [nTPM]":"98.1","Tissue RNA - cervix [nTPM]":"79.3","Tissue RNA - choroid plexus [nTPM]":"57.4","Tissue RNA - colon [nTPM]":"89.1","Tissue RNA - duodenum [nTPM]":"63.6","Tissue RNA - endometrium 1 [nTPM]":"85.8","Tissue RNA - epididymis [nTPM]":"64.2","Tissue RNA - esophagus [nTPM]":"97.1","Tissue RNA - fallopian tube [nTPM]":"71.5","Tissue RNA - gallbladder [nTPM]":"53.6","Tissue RNA - heart muscle [nTPM]":"96.0","Tissue RNA - hippocampal formation [nTPM]":"81.9","Tissue RNA - hypothalamus [nTPM]":"92.6","Tissue RNA - kidney [nTPM]":"77.4","Tissue RNA - liver [nTPM]":"102.4","Tissue RNA - lung [nTPM]":"102.3","Tissue RNA - lymph node [nTPM]":"60.9","Tissue RNA - medulla oblongata [nTPM]":"88.3","Tissue RNA - midbrain [nTPM]":"81.1","Tissue RNA - ovary [nTPM]":"78.5","Tissue RNA - pancreas [nTPM]":"150.1","Tissue RNA - parathyroid gland [nTPM]":"102.1","Tissue RNA - pituitary gland [nTPM]":"88.6","Tissue RNA - placenta [nTPM]":"76.2","Tissue RNA - pons [nTPM]":"91.1","Tissue RNA - prostate [nTPM]":"66.2","Tissue RNA - rectum [nTPM]":"74.8","Tissue RNA - retina [nTPM]":"68.0","Tissue RNA - salivary gland [nTPM]":"86.1","Tissue RNA - seminal vesicle [nTPM]":"73.9","Tissue RNA - skeletal muscle [nTPM]":"113.3","Tissue RNA - skin 1 [nTPM]":"111.9","Tissue RNA - small intestine [nTPM]":"69.9","Tissue RNA - smooth muscle [nTPM]":"79.3","Tissue RNA - spinal cord [nTPM]":"72.9","Tissue RNA - spleen [nTPM]":"64.5","Tissue RNA - stomach 1 [nTPM]":"112.4","Tissue RNA - testis [nTPM]":"46.3","Tissue RNA - thalamus [nTPM]":"78.1","Tissue RNA - thymus [nTPM]":"66.7","Tissue RNA - thyroid gland [nTPM]":"139.8","Tissue RNA - tongue [nTPM]":"87.9","Tissue RNA - tonsil [nTPM]":"76.4","Tissue RNA - urinary bladder [nTPM]":"88.3","Tissue RNA - vagina [nTPM]":"82.1","Tissue RNA - white matter [nTPM]":"90.9","Cell RNA - A-431 [nTPM]":"208.5","Cell RNA - A549 [nTPM]":"82.1","Cell RNA - AF22 [nTPM]":"152.3","Cell RNA - AN3-CA [nTPM]":"230.3","Cell RNA - ASC diff [nTPM]":"224.2","Cell RNA - ASC TERT1 [nTPM]":"201.4","Cell RNA - BEWO [nTPM]":"261.6","Cell RNA - BJ [nTPM]":"213.1","Cell RNA - BJ hTERT+ [nTPM]":"222.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"183.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"227.1","Cell RNA - CACO-2 [nTPM]":"161.4","Cell RNA - CAPAN-2 [nTPM]":"62.7","Cell RNA - Daudi [nTPM]":"224.1","Cell RNA - EFO-21 [nTPM]":"107.7","Cell RNA - fHDF\/TERT166 [nTPM]":"307.2","Cell RNA - GAMG [nTPM]":"102.8","Cell RNA - HaCaT [nTPM]":"111.6","Cell RNA - HAP1 [nTPM]":"241.1","Cell RNA - HBEC3-KT [nTPM]":"305.9","Cell RNA - HBF TERT88 [nTPM]":"212.4","Cell RNA - HDLM-2 [nTPM]":"159.0","Cell RNA - HEK 293 [nTPM]":"150.4","Cell RNA - HEL [nTPM]":"86.6","Cell RNA - HeLa [nTPM]":"96.3","Cell RNA - Hep G2 [nTPM]":"118.4","Cell RNA - HHSteC [nTPM]":"448.1","Cell RNA - HL-60 [nTPM]":"110.5","Cell RNA - HMC-1 [nTPM]":"93.7","Cell RNA - HSkMC [nTPM]":"249.4","Cell RNA - hTCEpi [nTPM]":"526.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"217.1","Cell RNA - hTERT-HME1 [nTPM]":"467.7","Cell RNA - hTERT-RPE1 [nTPM]":"155.9","Cell RNA - HUVEC TERT2 [nTPM]":"221.9","Cell RNA - JURKAT [nTPM]":"279.5","Cell RNA - K-562 [nTPM]":"201.9","Cell RNA - Karpas-707 [nTPM]":"273.2","Cell RNA - LHCN-M2 [nTPM]":"181.3","Cell RNA - MCF7 [nTPM]":"205.8","Cell RNA - MOLT-4 [nTPM]":"124.8","Cell RNA - NB-4 [nTPM]":"57.5","Cell RNA - NTERA-2 [nTPM]":"63.4","Cell RNA - OE19 [nTPM]":"125.6","Cell RNA - PC-3 [nTPM]":"193.5","Cell RNA - REH [nTPM]":"101.1","Cell RNA - RH-30 [nTPM]":"192.5","Cell RNA - RPMI-8226 [nTPM]":"102.6","Cell RNA - RPTEC TERT1 [nTPM]":"139.9","Cell RNA - RT4 [nTPM]":"111.0","Cell RNA - SCLC-21H [nTPM]":"210.0","Cell RNA - SH-SY5Y [nTPM]":"111.2","Cell RNA - SiHa [nTPM]":"102.5","Cell RNA - SK-BR-3 [nTPM]":"164.7","Cell RNA - SK-MEL-30 [nTPM]":"601.4","Cell RNA - SuSa [nTPM]":"114.9","Cell RNA - T-47d [nTPM]":"93.5","Cell RNA - THP-1 [nTPM]":"131.2","Cell RNA - TIME [nTPM]":"174.5","Cell RNA - U-138 MG [nTPM]":"108.3","Cell RNA - U-2 OS [nTPM]":"135.0","Cell RNA - U-2197 [nTPM]":"155.5","Cell RNA - U-251 MG [nTPM]":"151.8","Cell RNA - U-266\/70 [nTPM]":"205.6","Cell RNA - U-266\/84 [nTPM]":"89.6","Cell RNA - U-698 [nTPM]":"183.7","Cell RNA - U-87 MG [nTPM]":"341.3","Cell RNA - U-937 [nTPM]":"119.8","Cell RNA - WM-115 [nTPM]":"376.7","Blood RNA - basophil [nTPM]":"191.5","Blood RNA - classical monocyte [nTPM]":"193.9","Blood RNA - eosinophil [nTPM]":"219.6","Blood RNA - gdT-cell [nTPM]":"228.6","Blood RNA - intermediate monocyte [nTPM]":"212.2","Blood RNA - MAIT T-cell [nTPM]":"240.0","Blood RNA - memory B-cell [nTPM]":"235.8","Blood RNA - memory CD4 T-cell [nTPM]":"238.2","Blood RNA - memory CD8 T-cell [nTPM]":"227.3","Blood RNA - myeloid DC [nTPM]":"198.8","Blood RNA - naive B-cell [nTPM]":"252.4","Blood RNA - naive CD4 T-cell [nTPM]":"246.4","Blood RNA - naive CD8 T-cell [nTPM]":"229.4","Blood RNA - neutrophil [nTPM]":"89.7","Blood RNA - NK-cell [nTPM]":"193.5","Blood RNA - non-classical monocyte [nTPM]":"226.6","Blood RNA - plasmacytoid DC [nTPM]":"128.2","Blood RNA - T-reg [nTPM]":"300.9","Blood RNA - total PBMC [nTPM]":"460.5","Brain RNA - amygdala [nTPM]":"78.6","Brain RNA - basal ganglia [nTPM]":"78.6","Brain RNA - cerebellum [nTPM]":"77.2","Brain RNA - cerebral cortex [nTPM]":"98.1","Brain RNA - hippocampal formation [nTPM]":"81.9","Brain RNA - hypothalamus [nTPM]":"92.6","Brain RNA - medulla oblongata [nTPM]":"88.3","Brain RNA - midbrain [nTPM]":"81.1","Brain RNA - pons [nTPM]":"91.1","Brain RNA - spinal cord [nTPM]":"72.9","Brain RNA - thalamus [nTPM]":"78.1","Brain RNA - white matter [nTPM]":"90.9","Single Cell Type RNA - Adipocytes [nTPM]":"30.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"6.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"98.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"186.0","Single Cell Type RNA - dendritic cells [nTPM]":"28.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"9.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"147.6","Single Cell Type RNA - Fibroblasts [nTPM]":"23.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"88.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"4.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"15.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"188.4","Single Cell Type RNA - T-cells [nTPM]":"5.9","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SARS2","Gene synonym":["FLJ20450","mtSerRS","SARS","SARSM","SerRSmt","SERS","SYS"],"Ensembl":"ENSG00000104835","Gene description":"Seryl-tRNA synthetase 2, mitochondrial","Uniprot":["Q9NP81"],"Chromosome":"19","Position":"38915266-38930763","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"40.1","Late spermatids":"56.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052730","HPA056957"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA052730":"AB_2681929","HPA056957":"AB_2683286"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.3","Tissue RNA - adrenal gland [nTPM]":"17.3","Tissue RNA - amygdala [nTPM]":"4.2","Tissue RNA - appendix [nTPM]":"7.2","Tissue RNA - basal ganglia [nTPM]":"4.7","Tissue RNA - bone marrow [nTPM]":"9.3","Tissue RNA - breast [nTPM]":"8.2","Tissue RNA - cerebellum [nTPM]":"4.4","Tissue RNA - cerebral cortex [nTPM]":"6.8","Tissue RNA - cervix [nTPM]":"9.7","Tissue RNA - choroid plexus [nTPM]":"3.6","Tissue RNA - colon [nTPM]":"10.1","Tissue RNA - duodenum [nTPM]":"9.3","Tissue RNA - endometrium 1 [nTPM]":"9.3","Tissue RNA - epididymis [nTPM]":"2.8","Tissue RNA - esophagus [nTPM]":"14.3","Tissue RNA - fallopian tube [nTPM]":"8.5","Tissue RNA - gallbladder [nTPM]":"5.9","Tissue RNA - heart muscle [nTPM]":"12.4","Tissue RNA - hippocampal formation [nTPM]":"4.7","Tissue RNA - hypothalamus [nTPM]":"4.4","Tissue RNA - kidney [nTPM]":"14.6","Tissue RNA - liver [nTPM]":"18.7","Tissue RNA - lung [nTPM]":"6.6","Tissue RNA - lymph node [nTPM]":"9.8","Tissue RNA - medulla oblongata [nTPM]":"5.0","Tissue RNA - midbrain [nTPM]":"4.4","Tissue RNA - ovary [nTPM]":"9.8","Tissue RNA - pancreas [nTPM]":"15.9","Tissue RNA - parathyroid gland [nTPM]":"7.8","Tissue RNA - pituitary gland [nTPM]":"11.9","Tissue RNA - placenta [nTPM]":"7.6","Tissue RNA - pons [nTPM]":"5.3","Tissue RNA - prostate [nTPM]":"12.2","Tissue RNA - rectum [nTPM]":"5.3","Tissue RNA - retina [nTPM]":"2.3","Tissue RNA - salivary gland [nTPM]":"11.3","Tissue RNA - seminal vesicle [nTPM]":"6.2","Tissue RNA - skeletal muscle [nTPM]":"16.4","Tissue RNA - skin 1 [nTPM]":"12.3","Tissue RNA - small intestine [nTPM]":"10.2","Tissue RNA - smooth muscle [nTPM]":"5.1","Tissue RNA - spinal cord [nTPM]":"4.2","Tissue RNA - spleen [nTPM]":"12.0","Tissue RNA - stomach 1 [nTPM]":"11.9","Tissue RNA - testis [nTPM]":"10.7","Tissue RNA - thalamus [nTPM]":"4.4","Tissue RNA - thymus [nTPM]":"7.5","Tissue RNA - thyroid gland [nTPM]":"14.4","Tissue RNA - tongue [nTPM]":"11.5","Tissue RNA - tonsil [nTPM]":"6.6","Tissue RNA - urinary bladder [nTPM]":"9.4","Tissue RNA - vagina [nTPM]":"9.6","Tissue RNA - white matter [nTPM]":"5.4","Cell RNA - A-431 [nTPM]":"17.6","Cell RNA - A549 [nTPM]":"47.3","Cell RNA - AF22 [nTPM]":"15.5","Cell RNA - AN3-CA [nTPM]":"10.7","Cell RNA - ASC diff [nTPM]":"5.8","Cell RNA - ASC TERT1 [nTPM]":"13.3","Cell RNA - BEWO [nTPM]":"23.7","Cell RNA - BJ [nTPM]":"10.7","Cell RNA - BJ hTERT+ [nTPM]":"12.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.7","Cell RNA - CACO-2 [nTPM]":"36.0","Cell RNA - CAPAN-2 [nTPM]":"18.4","Cell RNA - Daudi [nTPM]":"17.2","Cell RNA - EFO-21 [nTPM]":"16.3","Cell RNA - fHDF\/TERT166 [nTPM]":"12.5","Cell RNA - GAMG [nTPM]":"9.7","Cell RNA - HaCaT [nTPM]":"13.9","Cell RNA - HAP1 [nTPM]":"14.7","Cell RNA - HBEC3-KT [nTPM]":"29.2","Cell RNA - HBF TERT88 [nTPM]":"5.3","Cell RNA - HDLM-2 [nTPM]":"12.7","Cell RNA - HEK 293 [nTPM]":"24.4","Cell RNA - HEL [nTPM]":"33.7","Cell RNA - HeLa [nTPM]":"17.7","Cell RNA - Hep G2 [nTPM]":"32.0","Cell RNA - HHSteC [nTPM]":"15.4","Cell RNA - HL-60 [nTPM]":"29.1","Cell RNA - HMC-1 [nTPM]":"31.9","Cell RNA - HSkMC [nTPM]":"20.7","Cell RNA - hTCEpi [nTPM]":"13.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.5","Cell RNA - hTERT-HME1 [nTPM]":"7.6","Cell RNA - hTERT-RPE1 [nTPM]":"9.5","Cell RNA - HUVEC TERT2 [nTPM]":"14.2","Cell RNA - JURKAT [nTPM]":"26.3","Cell RNA - K-562 [nTPM]":"29.9","Cell RNA - Karpas-707 [nTPM]":"14.2","Cell RNA - LHCN-M2 [nTPM]":"10.6","Cell RNA - MCF7 [nTPM]":"28.4","Cell RNA - MOLT-4 [nTPM]":"21.4","Cell RNA - NB-4 [nTPM]":"20.7","Cell RNA - NTERA-2 [nTPM]":"18.5","Cell RNA - OE19 [nTPM]":"21.6","Cell RNA - PC-3 [nTPM]":"8.5","Cell RNA - REH [nTPM]":"31.2","Cell RNA - RH-30 [nTPM]":"16.4","Cell RNA - RPMI-8226 [nTPM]":"18.6","Cell RNA - RPTEC TERT1 [nTPM]":"20.5","Cell RNA - RT4 [nTPM]":"36.2","Cell RNA - SCLC-21H [nTPM]":"29.1","Cell RNA - SH-SY5Y [nTPM]":"18.1","Cell RNA - SiHa [nTPM]":"14.2","Cell RNA - SK-BR-3 [nTPM]":"32.7","Cell RNA - SK-MEL-30 [nTPM]":"8.9","Cell RNA - SuSa [nTPM]":"4.6","Cell RNA - T-47d [nTPM]":"21.8","Cell RNA - THP-1 [nTPM]":"19.1","Cell RNA - TIME [nTPM]":"11.4","Cell RNA - U-138 MG [nTPM]":"13.7","Cell RNA - U-2 OS [nTPM]":"17.7","Cell RNA - U-2197 [nTPM]":"11.7","Cell RNA - U-251 MG [nTPM]":"15.1","Cell RNA - U-266\/70 [nTPM]":"11.0","Cell RNA - U-266\/84 [nTPM]":"7.1","Cell RNA - U-698 [nTPM]":"13.2","Cell RNA - U-87 MG [nTPM]":"10.9","Cell RNA - U-937 [nTPM]":"18.5","Cell RNA - WM-115 [nTPM]":"13.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"8.0","Blood RNA - eosinophil [nTPM]":"1.0","Blood RNA - gdT-cell [nTPM]":"14.2","Blood RNA - intermediate monocyte [nTPM]":"14.4","Blood RNA - MAIT T-cell [nTPM]":"11.5","Blood RNA - memory B-cell [nTPM]":"12.0","Blood RNA - memory CD4 T-cell [nTPM]":"10.7","Blood RNA - memory CD8 T-cell [nTPM]":"14.7","Blood RNA - myeloid DC [nTPM]":"25.2","Blood RNA - naive B-cell [nTPM]":"10.7","Blood RNA - naive CD4 T-cell [nTPM]":"7.5","Blood RNA - naive CD8 T-cell [nTPM]":"8.6","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"14.0","Blood RNA - non-classical monocyte [nTPM]":"13.7","Blood RNA - plasmacytoid DC [nTPM]":"9.9","Blood RNA - T-reg [nTPM]":"13.4","Blood RNA - total PBMC [nTPM]":"8.9","Brain RNA - amygdala [nTPM]":"4.2","Brain RNA - basal ganglia [nTPM]":"4.7","Brain RNA - cerebellum [nTPM]":"4.4","Brain RNA - cerebral cortex [nTPM]":"6.8","Brain RNA - hippocampal formation [nTPM]":"4.7","Brain RNA - hypothalamus [nTPM]":"4.4","Brain RNA - medulla oblongata [nTPM]":"5.0","Brain RNA - midbrain [nTPM]":"4.4","Brain RNA - pons [nTPM]":"5.3","Brain RNA - spinal cord [nTPM]":"4.2","Brain RNA - thalamus [nTPM]":"4.4","Brain RNA - white matter [nTPM]":"5.4","Single Cell Type RNA - Adipocytes [nTPM]":"2.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.9","Single Cell Type RNA - Astrocytes [nTPM]":"6.2","Single Cell Type RNA - B-cells [nTPM]":"8.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"8.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"6.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"40.1","Single Cell Type RNA - dendritic cells [nTPM]":"5.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"15.5","Single Cell Type RNA - Early spermatids [nTPM]":"15.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.6","Single Cell Type RNA - Endothelial cells [nTPM]":"3.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.4","Single Cell Type RNA - Erythroid cells [nTPM]":"13.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"23.0","Single Cell Type RNA - Fibroblasts [nTPM]":"4.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.9","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"7.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"10.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.9","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.2","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"6.7","Single Cell Type RNA - Langerhans cells [nTPM]":"4.2","Single Cell Type RNA - Late spermatids [nTPM]":"56.9","Single Cell Type RNA - Leydig cells [nTPM]":"4.7","Single Cell Type RNA - Macrophages [nTPM]":"4.8","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"7.7","Single Cell Type RNA - Muller glia cells [nTPM]":"3.1","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.4","Single Cell Type RNA - Paneth cells [nTPM]":"5.6","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"10.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.2","Single Cell Type RNA - Spermatocytes [nTPM]":"1.9","Single Cell Type RNA - Spermatogonia [nTPM]":"8.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"29.1","Single Cell Type RNA - T-cells [nTPM]":"7.4","Single Cell Type RNA - Theca cells [nTPM]":"10.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.8","Single Cell Type RNA - Urothelial cells [nTPM]":"3.2"},{"Gene":"SAT1","Gene synonym":["SAT","SSAT"],"Ensembl":"ENSG00000130066","Gene description":"Spermidine\/spermine N1-acetyltransferase 1","Uniprot":["P21673"],"Chromosome":"X","Position":"23783173-23786226","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"8151.3","Langerhans cells":"13855.3","Prostatic glandular cells":"7419.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"3422.0","non-classical monocyte":"2519.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"3422.0","monocytes":"2519.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HBEC3-KT":"551.5","hTERT-HME1":"821.9","RPTEC TERT1":"694.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB047343","HPA055312","CAB069914"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB047343":null,"CAB069914":"AB_830224","HPA055312":"AB_2682781"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.87e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.90e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.52e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.97e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Tissue RNA - adipose tissue [nTPM]":"843.8","Tissue RNA - adrenal gland [nTPM]":"307.2","Tissue RNA - amygdala [nTPM]":"171.6","Tissue RNA - appendix [nTPM]":"568.4","Tissue RNA - basal ganglia [nTPM]":"175.0","Tissue RNA - bone marrow [nTPM]":"1484.9","Tissue RNA - breast [nTPM]":"454.0","Tissue RNA - cerebellum [nTPM]":"167.0","Tissue RNA - cerebral cortex [nTPM]":"279.5","Tissue RNA - cervix [nTPM]":"337.8","Tissue RNA - choroid plexus [nTPM]":"219.7","Tissue RNA - colon [nTPM]":"339.0","Tissue RNA - duodenum [nTPM]":"630.9","Tissue RNA - endometrium 1 [nTPM]":"319.0","Tissue RNA - epididymis [nTPM]":"170.8","Tissue RNA - esophagus [nTPM]":"407.4","Tissue RNA - fallopian tube [nTPM]":"322.7","Tissue RNA - gallbladder [nTPM]":"600.8","Tissue RNA - heart muscle [nTPM]":"604.4","Tissue RNA - hippocampal formation [nTPM]":"171.8","Tissue RNA - hypothalamus [nTPM]":"202.0","Tissue RNA - kidney [nTPM]":"739.5","Tissue RNA - liver [nTPM]":"885.0","Tissue RNA - lung [nTPM]":"1252.9","Tissue RNA - lymph node [nTPM]":"431.3","Tissue RNA - medulla oblongata [nTPM]":"186.2","Tissue RNA - midbrain [nTPM]":"178.6","Tissue RNA - ovary [nTPM]":"197.9","Tissue RNA - pancreas [nTPM]":"229.3","Tissue RNA - parathyroid gland [nTPM]":"268.7","Tissue RNA - pituitary gland [nTPM]":"548.5","Tissue RNA - placenta [nTPM]":"603.5","Tissue RNA - pons [nTPM]":"188.6","Tissue RNA - prostate [nTPM]":"413.1","Tissue RNA - rectum [nTPM]":"364.3","Tissue RNA - retina [nTPM]":"108.3","Tissue RNA - salivary gland [nTPM]":"786.6","Tissue RNA - seminal vesicle [nTPM]":"342.2","Tissue RNA - skeletal muscle [nTPM]":"66.2","Tissue RNA - skin 1 [nTPM]":"200.1","Tissue RNA - small intestine [nTPM]":"509.5","Tissue RNA - smooth muscle [nTPM]":"175.4","Tissue RNA - spinal cord [nTPM]":"185.5","Tissue RNA - spleen [nTPM]":"706.6","Tissue RNA - stomach 1 [nTPM]":"562.6","Tissue RNA - testis [nTPM]":"116.2","Tissue RNA - thalamus [nTPM]":"197.7","Tissue RNA - thymus [nTPM]":"231.8","Tissue RNA - thyroid gland [nTPM]":"757.0","Tissue RNA - tongue [nTPM]":"79.0","Tissue RNA - tonsil [nTPM]":"333.4","Tissue RNA - urinary bladder [nTPM]":"536.2","Tissue RNA - vagina [nTPM]":"241.6","Tissue RNA - white matter [nTPM]":"206.6","Cell RNA - A-431 [nTPM]":"62.2","Cell RNA - A549 [nTPM]":"123.1","Cell RNA - AF22 [nTPM]":"30.8","Cell RNA - AN3-CA [nTPM]":"48.3","Cell RNA - ASC diff [nTPM]":"256.0","Cell RNA - ASC TERT1 [nTPM]":"103.8","Cell RNA - BEWO [nTPM]":"83.6","Cell RNA - BJ [nTPM]":"89.2","Cell RNA - BJ hTERT+ [nTPM]":"149.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"50.2","Cell RNA - CACO-2 [nTPM]":"59.0","Cell RNA - CAPAN-2 [nTPM]":"179.3","Cell RNA - Daudi [nTPM]":"102.7","Cell RNA - EFO-21 [nTPM]":"160.0","Cell RNA - fHDF\/TERT166 [nTPM]":"21.1","Cell RNA - GAMG [nTPM]":"172.4","Cell RNA - HaCaT [nTPM]":"91.9","Cell RNA - HAP1 [nTPM]":"16.4","Cell RNA - HBEC3-KT [nTPM]":"551.5","Cell RNA - HBF TERT88 [nTPM]":"78.8","Cell RNA - HDLM-2 [nTPM]":"34.1","Cell RNA - HEK 293 [nTPM]":"74.3","Cell RNA - HEL [nTPM]":"49.9","Cell RNA - HeLa [nTPM]":"60.0","Cell RNA - Hep G2 [nTPM]":"503.5","Cell RNA - HHSteC [nTPM]":"327.5","Cell RNA - HL-60 [nTPM]":"48.8","Cell RNA - HMC-1 [nTPM]":"46.1","Cell RNA - HSkMC [nTPM]":"216.2","Cell RNA - hTCEpi [nTPM]":"412.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"169.0","Cell RNA - hTERT-HME1 [nTPM]":"821.9","Cell RNA - hTERT-RPE1 [nTPM]":"197.2","Cell RNA - HUVEC TERT2 [nTPM]":"181.5","Cell RNA - JURKAT [nTPM]":"16.4","Cell RNA - K-562 [nTPM]":"21.4","Cell RNA - Karpas-707 [nTPM]":"88.4","Cell RNA - LHCN-M2 [nTPM]":"63.8","Cell RNA - MCF7 [nTPM]":"59.1","Cell RNA - MOLT-4 [nTPM]":"35.9","Cell RNA - NB-4 [nTPM]":"219.1","Cell RNA - NTERA-2 [nTPM]":"20.6","Cell RNA - OE19 [nTPM]":"455.2","Cell RNA - PC-3 [nTPM]":"56.3","Cell RNA - REH [nTPM]":"30.0","Cell RNA - RH-30 [nTPM]":"19.8","Cell RNA - RPMI-8226 [nTPM]":"126.1","Cell RNA - RPTEC TERT1 [nTPM]":"694.6","Cell RNA - RT4 [nTPM]":"126.0","Cell RNA - SCLC-21H [nTPM]":"8.7","Cell RNA - SH-SY5Y [nTPM]":"8.9","Cell RNA - SiHa [nTPM]":"91.2","Cell RNA - SK-BR-3 [nTPM]":"204.8","Cell RNA - SK-MEL-30 [nTPM]":"179.2","Cell RNA - SuSa [nTPM]":"222.3","Cell RNA - T-47d [nTPM]":"31.5","Cell RNA - THP-1 [nTPM]":"10.7","Cell RNA - TIME [nTPM]":"68.9","Cell RNA - U-138 MG [nTPM]":"175.6","Cell RNA - U-2 OS [nTPM]":"8.9","Cell RNA - U-2197 [nTPM]":"106.6","Cell RNA - U-251 MG [nTPM]":"44.7","Cell RNA - U-266\/70 [nTPM]":"37.1","Cell RNA - U-266\/84 [nTPM]":"9.6","Cell RNA - U-698 [nTPM]":"23.1","Cell RNA - U-87 MG [nTPM]":"104.8","Cell RNA - U-937 [nTPM]":"28.8","Cell RNA - WM-115 [nTPM]":"34.2","Blood RNA - basophil [nTPM]":"557.6","Blood RNA - classical monocyte [nTPM]":"720.4","Blood RNA - eosinophil [nTPM]":"478.9","Blood RNA - gdT-cell [nTPM]":"66.0","Blood RNA - intermediate monocyte [nTPM]":"1930.3","Blood RNA - MAIT T-cell [nTPM]":"41.6","Blood RNA - memory B-cell [nTPM]":"125.3","Blood RNA - memory CD4 T-cell [nTPM]":"77.4","Blood RNA - memory CD8 T-cell [nTPM]":"53.8","Blood RNA - myeloid DC [nTPM]":"324.8","Blood RNA - naive B-cell [nTPM]":"79.1","Blood RNA - naive CD4 T-cell [nTPM]":"45.9","Blood RNA - naive CD8 T-cell [nTPM]":"53.3","Blood RNA - neutrophil [nTPM]":"3422.0","Blood RNA - NK-cell [nTPM]":"33.8","Blood RNA - non-classical monocyte [nTPM]":"2519.0","Blood RNA - plasmacytoid DC [nTPM]":"161.2","Blood RNA - T-reg [nTPM]":"231.5","Blood RNA - total PBMC [nTPM]":"742.5","Brain RNA - amygdala [nTPM]":"171.6","Brain RNA - basal ganglia [nTPM]":"175.0","Brain RNA - cerebellum [nTPM]":"167.0","Brain RNA - cerebral cortex [nTPM]":"279.5","Brain RNA - hippocampal formation [nTPM]":"171.8","Brain RNA - hypothalamus [nTPM]":"202.0","Brain RNA - medulla oblongata [nTPM]":"186.2","Brain RNA - midbrain [nTPM]":"178.6","Brain RNA - pons [nTPM]":"188.6","Brain RNA - spinal cord [nTPM]":"185.5","Brain RNA - thalamus [nTPM]":"197.7","Brain RNA - white matter [nTPM]":"206.6","Single Cell Type RNA - Adipocytes [nTPM]":"798.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"734.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1585.4","Single Cell Type RNA - Astrocytes [nTPM]":"98.9","Single Cell Type RNA - B-cells [nTPM]":"875.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2435.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3753.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8151.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1203.6","Single Cell Type RNA - Bipolar cells [nTPM]":"54.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"895.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"574.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"454.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"574.7","Single Cell Type RNA - Club cells [nTPM]":"5509.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"829.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"116.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"853.1","Single Cell Type RNA - dendritic cells [nTPM]":"409.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"1249.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"1189.5","Single Cell Type RNA - Ductal cells [nTPM]":"5869.5","Single Cell Type RNA - Early spermatids [nTPM]":"17.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3940.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"859.6","Single Cell Type RNA - Endothelial cells [nTPM]":"1554.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"526.9","Single Cell Type RNA - Erythroid cells [nTPM]":"195.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"40.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3065.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1643.7","Single Cell Type RNA - Fibroblasts [nTPM]":"1211.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1347.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5651.2","Single Cell Type RNA - granulocytes [nTPM]":"870.6","Single Cell Type RNA - Granulosa cells [nTPM]":"110.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"558.3","Single Cell Type RNA - Hepatocytes [nTPM]":"994.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"2115.2","Single Cell Type RNA - Horizontal cells [nTPM]":"72.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"77.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"852.3","Single Cell Type RNA - Ionocytes [nTPM]":"3733.2","Single Cell Type RNA - Kupffer cells [nTPM]":"4693.0","Single Cell Type RNA - Langerhans cells [nTPM]":"13855.3","Single Cell Type RNA - Late spermatids [nTPM]":"55.2","Single Cell Type RNA - Leydig cells [nTPM]":"165.3","Single Cell Type RNA - Macrophages [nTPM]":"5207.7","Single Cell Type RNA - Melanocytes [nTPM]":"3922.0","Single Cell Type RNA - Microglial cells [nTPM]":"213.6","Single Cell Type RNA - monocytes [nTPM]":"5274.6","Single Cell Type RNA - Muller glia cells [nTPM]":"501.9","Single Cell Type RNA - NK-cells [nTPM]":"189.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"90.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2774.1","Single Cell Type RNA - Paneth cells [nTPM]":"1293.8","Single Cell Type RNA - Peritubular cells [nTPM]":"92.2","Single Cell Type RNA - Plasma cells [nTPM]":"1091.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7419.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1851.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2065.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4274.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"114.4","Single Cell Type RNA - Sertoli cells [nTPM]":"151.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"765.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"857.5","Single Cell Type RNA - Spermatocytes [nTPM]":"31.6","Single Cell Type RNA - Spermatogonia [nTPM]":"14.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1022.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1468.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2880.9","Single Cell Type RNA - T-cells [nTPM]":"899.3","Single Cell Type RNA - Theca cells [nTPM]":"260.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"804.4","Single Cell Type RNA - Urothelial cells [nTPM]":"6549.5"},{"Gene":"SC5D","Gene synonym":["SC5DL"],"Ensembl":"ENSG00000109929","Gene description":"Sterol-C5-desaturase","Uniprot":["O75845"],"Chromosome":"11","Position":"121292681-121313410","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"393.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatic stellate cells":"141.0","Hepatocytes":"307.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066283","HPA070248"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Endoplasmic reticulum","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":["Nucleoplasm","Endoplasmic reticulum"],"Subcellular additional location":["Plasma membrane","Cytosol"],"Antibody RRID":{"HPA066283":"AB_2685648","HPA070248":"AB_2686240"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.30e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.98e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.07e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Tissue RNA - adipose tissue [nTPM]":"28.6","Tissue RNA - adrenal gland [nTPM]":"35.3","Tissue RNA - amygdala [nTPM]":"18.4","Tissue RNA - appendix [nTPM]":"12.6","Tissue RNA - basal ganglia [nTPM]":"20.4","Tissue RNA - bone marrow [nTPM]":"5.7","Tissue RNA - breast [nTPM]":"56.6","Tissue RNA - cerebellum [nTPM]":"37.1","Tissue RNA - cerebral cortex [nTPM]":"29.3","Tissue RNA - cervix [nTPM]":"20.7","Tissue RNA - choroid plexus [nTPM]":"17.6","Tissue RNA - colon [nTPM]":"23.2","Tissue RNA - duodenum [nTPM]":"48.2","Tissue RNA - endometrium 1 [nTPM]":"15.1","Tissue RNA - epididymis [nTPM]":"73.2","Tissue RNA - esophagus [nTPM]":"39.6","Tissue RNA - fallopian tube [nTPM]":"16.5","Tissue RNA - gallbladder [nTPM]":"18.2","Tissue RNA - heart muscle [nTPM]":"22.0","Tissue RNA - hippocampal formation [nTPM]":"19.9","Tissue RNA - hypothalamus [nTPM]":"29.9","Tissue RNA - kidney [nTPM]":"49.1","Tissue RNA - liver [nTPM]":"393.6","Tissue RNA - lung [nTPM]":"24.6","Tissue RNA - lymph node [nTPM]":"13.5","Tissue RNA - medulla oblongata [nTPM]":"42.9","Tissue RNA - midbrain [nTPM]":"28.0","Tissue RNA - ovary [nTPM]":"16.9","Tissue RNA - pancreas [nTPM]":"21.5","Tissue RNA - parathyroid gland [nTPM]":"48.6","Tissue RNA - pituitary gland [nTPM]":"15.6","Tissue RNA - placenta [nTPM]":"14.7","Tissue RNA - pons [nTPM]":"39.1","Tissue RNA - prostate [nTPM]":"101.4","Tissue RNA - rectum [nTPM]":"19.9","Tissue RNA - retina [nTPM]":"29.5","Tissue RNA - salivary gland [nTPM]":"22.4","Tissue RNA - seminal vesicle [nTPM]":"56.6","Tissue RNA - skeletal muscle [nTPM]":"7.7","Tissue RNA - skin 1 [nTPM]":"13.8","Tissue RNA - small intestine [nTPM]":"24.7","Tissue RNA - smooth muscle [nTPM]":"16.2","Tissue RNA - spinal cord [nTPM]":"32.2","Tissue RNA - spleen [nTPM]":"8.8","Tissue RNA - stomach 1 [nTPM]":"21.7","Tissue RNA - testis [nTPM]":"24.3","Tissue RNA - thalamus [nTPM]":"24.6","Tissue RNA - thymus [nTPM]":"13.5","Tissue RNA - thyroid gland [nTPM]":"23.9","Tissue RNA - tongue [nTPM]":"13.0","Tissue RNA - tonsil [nTPM]":"19.5","Tissue RNA - urinary bladder [nTPM]":"21.5","Tissue RNA - vagina [nTPM]":"27.1","Tissue RNA - white matter [nTPM]":"36.5","Cell RNA - A-431 [nTPM]":"26.5","Cell RNA - A549 [nTPM]":"14.3","Cell RNA - AF22 [nTPM]":"184.8","Cell RNA - AN3-CA [nTPM]":"39.5","Cell RNA - ASC diff [nTPM]":"72.1","Cell RNA - ASC TERT1 [nTPM]":"59.9","Cell RNA - BEWO [nTPM]":"27.8","Cell RNA - BJ [nTPM]":"27.8","Cell RNA - BJ hTERT+ [nTPM]":"53.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"32.4","Cell RNA - CACO-2 [nTPM]":"83.1","Cell RNA - CAPAN-2 [nTPM]":"95.9","Cell RNA - Daudi [nTPM]":"25.4","Cell RNA - EFO-21 [nTPM]":"89.0","Cell RNA - fHDF\/TERT166 [nTPM]":"32.3","Cell RNA - GAMG [nTPM]":"156.6","Cell RNA - HaCaT [nTPM]":"100.8","Cell RNA - HAP1 [nTPM]":"59.2","Cell RNA - HBEC3-KT [nTPM]":"70.9","Cell RNA - HBF TERT88 [nTPM]":"18.1","Cell RNA - HDLM-2 [nTPM]":"12.5","Cell RNA - HEK 293 [nTPM]":"80.0","Cell RNA - HEL [nTPM]":"34.6","Cell RNA - HeLa [nTPM]":"73.4","Cell RNA - Hep G2 [nTPM]":"64.4","Cell RNA - HHSteC [nTPM]":"57.9","Cell RNA - HL-60 [nTPM]":"24.8","Cell RNA - HMC-1 [nTPM]":"12.5","Cell RNA - HSkMC [nTPM]":"51.0","Cell RNA - hTCEpi [nTPM]":"57.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"60.4","Cell RNA - hTERT-HME1 [nTPM]":"60.2","Cell RNA - hTERT-RPE1 [nTPM]":"15.6","Cell RNA - HUVEC TERT2 [nTPM]":"29.8","Cell RNA - JURKAT [nTPM]":"22.8","Cell RNA - K-562 [nTPM]":"25.0","Cell RNA - Karpas-707 [nTPM]":"34.6","Cell RNA - LHCN-M2 [nTPM]":"89.0","Cell RNA - MCF7 [nTPM]":"27.4","Cell RNA - MOLT-4 [nTPM]":"9.4","Cell RNA - NB-4 [nTPM]":"29.2","Cell RNA - NTERA-2 [nTPM]":"59.8","Cell RNA - OE19 [nTPM]":"74.4","Cell RNA - PC-3 [nTPM]":"39.7","Cell RNA - REH [nTPM]":"13.2","Cell RNA - RH-30 [nTPM]":"51.0","Cell RNA - RPMI-8226 [nTPM]":"21.6","Cell RNA - RPTEC TERT1 [nTPM]":"133.6","Cell RNA - RT4 [nTPM]":"116.5","Cell RNA - SCLC-21H [nTPM]":"51.1","Cell RNA - SH-SY5Y [nTPM]":"28.8","Cell RNA - SiHa [nTPM]":"73.4","Cell RNA - SK-BR-3 [nTPM]":"14.6","Cell RNA - SK-MEL-30 [nTPM]":"38.0","Cell RNA - SuSa [nTPM]":"125.4","Cell RNA - T-47d [nTPM]":"62.2","Cell RNA - THP-1 [nTPM]":"38.6","Cell RNA - TIME [nTPM]":"58.3","Cell RNA - U-138 MG [nTPM]":"19.0","Cell RNA - U-2 OS [nTPM]":"29.7","Cell RNA - U-2197 [nTPM]":"32.5","Cell RNA - U-251 MG [nTPM]":"14.0","Cell RNA - U-266\/70 [nTPM]":"6.4","Cell RNA - U-266\/84 [nTPM]":"11.2","Cell RNA - U-698 [nTPM]":"33.3","Cell RNA - U-87 MG [nTPM]":"7.0","Cell RNA - U-937 [nTPM]":"49.5","Cell RNA - WM-115 [nTPM]":"33.5","Blood RNA - basophil [nTPM]":"7.8","Blood RNA - classical monocyte [nTPM]":"3.7","Blood RNA - eosinophil [nTPM]":"1.0","Blood RNA - gdT-cell [nTPM]":"3.5","Blood RNA - intermediate monocyte [nTPM]":"4.9","Blood RNA - MAIT T-cell [nTPM]":"5.9","Blood RNA - memory B-cell [nTPM]":"4.4","Blood RNA - memory CD4 T-cell [nTPM]":"4.7","Blood RNA - memory CD8 T-cell [nTPM]":"4.2","Blood RNA - myeloid DC [nTPM]":"6.5","Blood RNA - naive B-cell [nTPM]":"4.1","Blood RNA - naive CD4 T-cell [nTPM]":"6.8","Blood RNA - naive CD8 T-cell [nTPM]":"6.7","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"5.3","Blood RNA - non-classical monocyte [nTPM]":"3.6","Blood RNA - plasmacytoid DC [nTPM]":"7.7","Blood RNA - T-reg [nTPM]":"5.5","Blood RNA - total PBMC [nTPM]":"2.6","Brain RNA - amygdala [nTPM]":"18.4","Brain RNA - basal ganglia [nTPM]":"20.4","Brain RNA - cerebellum [nTPM]":"37.1","Brain RNA - cerebral cortex [nTPM]":"29.3","Brain RNA - hippocampal formation [nTPM]":"19.9","Brain RNA - hypothalamus [nTPM]":"29.9","Brain RNA - medulla oblongata [nTPM]":"42.9","Brain RNA - midbrain [nTPM]":"28.0","Brain RNA - pons [nTPM]":"39.1","Brain RNA - spinal cord [nTPM]":"32.2","Brain RNA - thalamus [nTPM]":"24.6","Brain RNA - white matter [nTPM]":"36.5","Single Cell Type RNA - Adipocytes [nTPM]":"10.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.9","Single Cell Type RNA - Astrocytes [nTPM]":"23.8","Single Cell Type RNA - B-cells [nTPM]":"62.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"49.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"48.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"26.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"33.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"20.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"40.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.9","Single Cell Type RNA - dendritic cells [nTPM]":"47.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"26.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"24.1","Single Cell Type RNA - Early spermatids [nTPM]":"3.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.8","Single Cell Type RNA - Endothelial cells [nTPM]":"15.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.4","Single Cell Type RNA - Erythroid cells [nTPM]":"18.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"29.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"28.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"16.7","Single Cell Type RNA - Fibroblasts [nTPM]":"16.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.6","Single Cell Type RNA - granulocytes [nTPM]":"17.7","Single Cell Type RNA - Granulosa cells [nTPM]":"11.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"141.0","Single Cell Type RNA - Hepatocytes [nTPM]":"307.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"21.0","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"29.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.3","Single Cell Type RNA - Ionocytes [nTPM]":"59.0","Single Cell Type RNA - Kupffer cells [nTPM]":"22.1","Single Cell Type RNA - Langerhans cells [nTPM]":"17.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"19.3","Single Cell Type RNA - Macrophages [nTPM]":"17.6","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"15.6","Single Cell Type RNA - Muller glia cells [nTPM]":"38.7","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"27.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"34.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.3","Single Cell Type RNA - Paneth cells [nTPM]":"18.8","Single Cell Type RNA - Peritubular cells [nTPM]":"17.0","Single Cell Type RNA - Plasma cells [nTPM]":"20.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"50.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"28.3","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.7","Single Cell Type RNA - Spermatocytes [nTPM]":"6.7","Single Cell Type RNA - Spermatogonia [nTPM]":"12.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"36.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"18.6","Single Cell Type RNA - T-cells [nTPM]":"56.5","Single Cell Type RNA - Theca cells [nTPM]":"42.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.3","Single Cell Type RNA - Urothelial cells [nTPM]":"54.4"},{"Gene":"SCARB2","Gene synonym":["CD36L2","HLGP85","LIMP-2","LIMPII","SR-BII"],"Ensembl":"ENSG00000138760","Gene description":"Scavenger receptor class B member 2","Uniprot":["Q14108"],"Chromosome":"4","Position":"76158737-76234536","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"12.5","classical monocyte":"14.1","intermediate monocyte":"26.0","myeloid DC":"8.2","non-classical monocyte":"24.9","plasmacytoid DC":"28.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"28.9","granulocytes":"12.5","monocytes":"26.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"499.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015415","HPA018014"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9200","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 35: Glandular cells - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB015415":"AB_831511","HPA018014":"AB_1852881"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.82e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Tissue RNA - adipose tissue [nTPM]":"60.6","Tissue RNA - adrenal gland [nTPM]":"24.0","Tissue RNA - amygdala [nTPM]":"33.5","Tissue RNA - appendix [nTPM]":"27.7","Tissue RNA - basal ganglia [nTPM]":"63.5","Tissue RNA - bone marrow [nTPM]":"7.3","Tissue RNA - breast [nTPM]":"56.7","Tissue RNA - cerebellum [nTPM]":"58.9","Tissue RNA - cerebral cortex [nTPM]":"38.9","Tissue RNA - cervix [nTPM]":"60.8","Tissue RNA - choroid plexus [nTPM]":"18.9","Tissue RNA - colon [nTPM]":"61.6","Tissue RNA - duodenum [nTPM]":"39.2","Tissue RNA - endometrium 1 [nTPM]":"44.1","Tissue RNA - epididymis [nTPM]":"58.4","Tissue RNA - esophagus [nTPM]":"33.9","Tissue RNA - fallopian tube [nTPM]":"45.4","Tissue RNA - gallbladder [nTPM]":"60.0","Tissue RNA - heart muscle [nTPM]":"61.6","Tissue RNA - hippocampal formation [nTPM]":"29.6","Tissue RNA - hypothalamus [nTPM]":"48.6","Tissue RNA - kidney [nTPM]":"46.8","Tissue RNA - liver [nTPM]":"89.9","Tissue RNA - lung [nTPM]":"77.1","Tissue RNA - lymph node [nTPM]":"20.2","Tissue RNA - medulla oblongata [nTPM]":"62.2","Tissue RNA - midbrain [nTPM]":"49.6","Tissue RNA - ovary [nTPM]":"58.9","Tissue RNA - pancreas [nTPM]":"58.9","Tissue RNA - parathyroid gland [nTPM]":"63.6","Tissue RNA - pituitary gland [nTPM]":"11.1","Tissue RNA - placenta [nTPM]":"80.2","Tissue RNA - pons [nTPM]":"62.5","Tissue RNA - prostate [nTPM]":"72.3","Tissue RNA - rectum [nTPM]":"64.0","Tissue RNA - retina [nTPM]":"53.2","Tissue RNA - salivary gland [nTPM]":"80.5","Tissue RNA - seminal vesicle [nTPM]":"55.4","Tissue RNA - skeletal muscle [nTPM]":"89.8","Tissue RNA - skin 1 [nTPM]":"26.0","Tissue RNA - small intestine [nTPM]":"49.1","Tissue RNA - smooth muscle [nTPM]":"57.8","Tissue RNA - spinal cord [nTPM]":"60.1","Tissue RNA - spleen [nTPM]":"47.0","Tissue RNA - stomach 1 [nTPM]":"60.7","Tissue RNA - testis [nTPM]":"19.4","Tissue RNA - thalamus [nTPM]":"50.7","Tissue RNA - thymus [nTPM]":"21.3","Tissue RNA - thyroid gland [nTPM]":"65.9","Tissue RNA - tongue [nTPM]":"81.3","Tissue RNA - tonsil [nTPM]":"20.6","Tissue RNA - urinary bladder [nTPM]":"65.3","Tissue RNA - vagina [nTPM]":"25.1","Tissue RNA - white matter [nTPM]":"92.9","Cell RNA - A-431 [nTPM]":"39.8","Cell RNA - A549 [nTPM]":"38.4","Cell RNA - AF22 [nTPM]":"48.9","Cell RNA - AN3-CA [nTPM]":"97.1","Cell RNA - ASC diff [nTPM]":"499.7","Cell RNA - ASC TERT1 [nTPM]":"242.0","Cell RNA - BEWO [nTPM]":"35.8","Cell RNA - BJ [nTPM]":"131.5","Cell RNA - BJ hTERT+ [nTPM]":"250.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"114.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"178.2","Cell RNA - CACO-2 [nTPM]":"72.5","Cell RNA - CAPAN-2 [nTPM]":"112.3","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"85.1","Cell RNA - fHDF\/TERT166 [nTPM]":"262.3","Cell RNA - GAMG [nTPM]":"109.6","Cell RNA - HaCaT [nTPM]":"28.3","Cell RNA - HAP1 [nTPM]":"28.3","Cell RNA - HBEC3-KT [nTPM]":"78.9","Cell RNA - HBF TERT88 [nTPM]":"96.0","Cell RNA - HDLM-2 [nTPM]":"138.8","Cell RNA - HEK 293 [nTPM]":"30.1","Cell RNA - HEL [nTPM]":"3.2","Cell RNA - HeLa [nTPM]":"32.9","Cell RNA - Hep G2 [nTPM]":"25.3","Cell RNA - HHSteC [nTPM]":"129.9","Cell RNA - HL-60 [nTPM]":"19.0","Cell RNA - HMC-1 [nTPM]":"12.1","Cell RNA - HSkMC [nTPM]":"186.9","Cell RNA - hTCEpi [nTPM]":"72.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"117.3","Cell RNA - hTERT-HME1 [nTPM]":"54.5","Cell RNA - hTERT-RPE1 [nTPM]":"268.9","Cell RNA - HUVEC TERT2 [nTPM]":"200.6","Cell RNA - JURKAT [nTPM]":"10.0","Cell RNA - K-562 [nTPM]":"15.6","Cell RNA - Karpas-707 [nTPM]":"188.6","Cell RNA - LHCN-M2 [nTPM]":"159.2","Cell RNA - MCF7 [nTPM]":"58.2","Cell RNA - MOLT-4 [nTPM]":"1.6","Cell RNA - NB-4 [nTPM]":"4.0","Cell RNA - NTERA-2 [nTPM]":"9.7","Cell RNA - OE19 [nTPM]":"120.3","Cell RNA - PC-3 [nTPM]":"23.6","Cell RNA - REH [nTPM]":"23.3","Cell RNA - RH-30 [nTPM]":"82.7","Cell RNA - RPMI-8226 [nTPM]":"42.0","Cell RNA - RPTEC TERT1 [nTPM]":"64.4","Cell RNA - RT4 [nTPM]":"43.6","Cell RNA - SCLC-21H [nTPM]":"101.3","Cell RNA - SH-SY5Y [nTPM]":"110.2","Cell RNA - SiHa [nTPM]":"104.7","Cell RNA - SK-BR-3 [nTPM]":"61.3","Cell RNA - SK-MEL-30 [nTPM]":"115.5","Cell RNA - SuSa [nTPM]":"49.3","Cell RNA - T-47d [nTPM]":"34.6","Cell RNA - THP-1 [nTPM]":"17.1","Cell RNA - TIME [nTPM]":"131.3","Cell RNA - U-138 MG [nTPM]":"125.9","Cell RNA - U-2 OS [nTPM]":"48.5","Cell RNA - U-2197 [nTPM]":"104.7","Cell RNA - U-251 MG [nTPM]":"47.5","Cell RNA - U-266\/70 [nTPM]":"167.6","Cell RNA - U-266\/84 [nTPM]":"98.8","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"158.1","Cell RNA - U-937 [nTPM]":"22.2","Cell RNA - WM-115 [nTPM]":"170.9","Blood RNA - basophil [nTPM]":"12.5","Blood RNA - classical monocyte [nTPM]":"14.1","Blood RNA - eosinophil [nTPM]":"3.1","Blood RNA - gdT-cell [nTPM]":"2.8","Blood RNA - intermediate monocyte [nTPM]":"26.0","Blood RNA - MAIT T-cell [nTPM]":"2.6","Blood RNA - memory B-cell [nTPM]":"3.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.5","Blood RNA - myeloid DC [nTPM]":"8.2","Blood RNA - naive B-cell [nTPM]":"3.0","Blood RNA - naive CD4 T-cell [nTPM]":"2.6","Blood RNA - naive CD8 T-cell [nTPM]":"4.3","Blood RNA - neutrophil [nTPM]":"1.9","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"24.9","Blood RNA - plasmacytoid DC [nTPM]":"28.9","Blood RNA - T-reg [nTPM]":"3.0","Blood RNA - total PBMC [nTPM]":"6.1","Brain RNA - amygdala [nTPM]":"33.5","Brain RNA - basal ganglia [nTPM]":"63.5","Brain RNA - cerebellum [nTPM]":"58.9","Brain RNA - cerebral cortex [nTPM]":"38.9","Brain RNA - hippocampal formation [nTPM]":"29.6","Brain RNA - hypothalamus [nTPM]":"48.6","Brain RNA - medulla oblongata [nTPM]":"62.2","Brain RNA - midbrain [nTPM]":"49.6","Brain RNA - pons [nTPM]":"62.5","Brain RNA - spinal cord [nTPM]":"60.1","Brain RNA - thalamus [nTPM]":"50.7","Brain RNA - white matter [nTPM]":"92.9","Single Cell Type RNA - Adipocytes [nTPM]":"89.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"176.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"52.4","Single Cell Type RNA - Astrocytes [nTPM]":"47.3","Single Cell Type RNA - B-cells [nTPM]":"20.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"24.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"90.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"64.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"34.1","Single Cell Type RNA - Bipolar cells [nTPM]":"109.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"69.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"36.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"53.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"87.2","Single Cell Type RNA - Club cells [nTPM]":"52.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"99.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"60.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"35.3","Single Cell Type RNA - dendritic cells [nTPM]":"43.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"109.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"119.9","Single Cell Type RNA - Early spermatids [nTPM]":"7.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"50.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"74.0","Single Cell Type RNA - Endothelial cells [nTPM]":"69.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"102.4","Single Cell Type RNA - Erythroid cells [nTPM]":"28.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"57.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"72.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"47.5","Single Cell Type RNA - Fibroblasts [nTPM]":"108.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"40.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"88.8","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"84.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"79.6","Single Cell Type RNA - Hepatocytes [nTPM]":"108.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"143.4","Single Cell Type RNA - Horizontal cells [nTPM]":"60.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"55.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"77.1","Single Cell Type RNA - Ionocytes [nTPM]":"44.7","Single Cell Type RNA - Kupffer cells [nTPM]":"165.7","Single Cell Type RNA - Langerhans cells [nTPM]":"27.5","Single Cell Type RNA - Late spermatids [nTPM]":"5.6","Single Cell Type RNA - Leydig cells [nTPM]":"45.4","Single Cell Type RNA - Macrophages [nTPM]":"76.2","Single Cell Type RNA - Melanocytes [nTPM]":"67.6","Single Cell Type RNA - Microglial cells [nTPM]":"38.4","Single Cell Type RNA - monocytes [nTPM]":"43.5","Single Cell Type RNA - Muller glia cells [nTPM]":"87.2","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"106.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"201.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"78.0","Single Cell Type RNA - Paneth cells [nTPM]":"68.3","Single Cell Type RNA - Peritubular cells [nTPM]":"66.5","Single Cell Type RNA - Plasma cells [nTPM]":"82.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"133.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"103.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"27.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"54.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"81.7","Single Cell Type RNA - Sertoli cells [nTPM]":"92.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"91.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"68.1","Single Cell Type RNA - Spermatocytes [nTPM]":"18.2","Single Cell Type RNA - Spermatogonia [nTPM]":"16.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"34.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"33.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"59.4","Single Cell Type RNA - T-cells [nTPM]":"16.3","Single Cell Type RNA - Theca cells [nTPM]":"56.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"55.3","Single Cell Type RNA - Urothelial cells [nTPM]":"93.4"},{"Gene":"SCP2","Gene synonym":[],"Ensembl":"ENSG00000116171","Gene description":"Sterol carrier protein 2","Uniprot":["P22307"],"Chromosome":"1","Position":"52927276-53051698","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"1116.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"1240.7","Proximal enterocytes":"769.0","Proximal tubular cells":"881.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027101","HPA027135","HPA027317"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Peroxisomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"640000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Peroxisomes"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA027101":"AB_1856634","HPA027135":"AB_1856633","HPA027317":"AB_10610422"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.05e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.85e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Tissue RNA - adipose tissue [nTPM]":"203.7","Tissue RNA - adrenal gland [nTPM]":"125.5","Tissue RNA - amygdala [nTPM]":"68.5","Tissue RNA - appendix [nTPM]":"92.7","Tissue RNA - basal ganglia [nTPM]":"71.6","Tissue RNA - bone marrow [nTPM]":"111.2","Tissue RNA - breast [nTPM]":"196.6","Tissue RNA - cerebellum [nTPM]":"74.2","Tissue RNA - cerebral cortex [nTPM]":"90.1","Tissue RNA - cervix [nTPM]":"153.8","Tissue RNA - choroid plexus [nTPM]":"79.2","Tissue RNA - colon [nTPM]":"256.7","Tissue RNA - duodenum [nTPM]":"336.3","Tissue RNA - endometrium 1 [nTPM]":"94.6","Tissue RNA - epididymis [nTPM]":"165.5","Tissue RNA - esophagus [nTPM]":"140.2","Tissue RNA - fallopian tube [nTPM]":"119.7","Tissue RNA - gallbladder [nTPM]":"144.6","Tissue RNA - heart muscle [nTPM]":"162.4","Tissue RNA - hippocampal formation [nTPM]":"65.8","Tissue RNA - hypothalamus [nTPM]":"76.1","Tissue RNA - kidney [nTPM]":"319.8","Tissue RNA - liver [nTPM]":"1116.8","Tissue RNA - lung [nTPM]":"140.6","Tissue RNA - lymph node [nTPM]":"106.0","Tissue RNA - medulla oblongata [nTPM]":"75.4","Tissue RNA - midbrain [nTPM]":"72.3","Tissue RNA - ovary [nTPM]":"94.5","Tissue RNA - pancreas [nTPM]":"119.2","Tissue RNA - parathyroid gland [nTPM]":"130.9","Tissue RNA - pituitary gland [nTPM]":"64.7","Tissue RNA - placenta [nTPM]":"79.0","Tissue RNA - pons [nTPM]":"77.9","Tissue RNA - prostate [nTPM]":"150.9","Tissue RNA - rectum [nTPM]":"270.5","Tissue RNA - retina [nTPM]":"76.6","Tissue RNA - salivary gland [nTPM]":"114.0","Tissue RNA - seminal vesicle [nTPM]":"97.3","Tissue RNA - skeletal muscle [nTPM]":"142.0","Tissue RNA - skin 1 [nTPM]":"130.6","Tissue RNA - small intestine [nTPM]":"305.7","Tissue RNA - smooth muscle [nTPM]":"112.9","Tissue RNA - spinal cord [nTPM]":"75.6","Tissue RNA - spleen [nTPM]":"83.9","Tissue RNA - stomach 1 [nTPM]":"234.4","Tissue RNA - testis [nTPM]":"63.4","Tissue RNA - thalamus [nTPM]":"74.7","Tissue RNA - thymus [nTPM]":"131.9","Tissue RNA - thyroid gland [nTPM]":"140.9","Tissue RNA - tongue [nTPM]":"152.8","Tissue RNA - tonsil [nTPM]":"125.5","Tissue RNA - urinary bladder [nTPM]":"139.2","Tissue RNA - vagina [nTPM]":"76.9","Tissue RNA - white matter [nTPM]":"78.9","Cell RNA - A-431 [nTPM]":"120.6","Cell RNA - A549 [nTPM]":"64.8","Cell RNA - AF22 [nTPM]":"85.5","Cell RNA - AN3-CA [nTPM]":"157.9","Cell RNA - ASC diff [nTPM]":"273.6","Cell RNA - ASC TERT1 [nTPM]":"232.6","Cell RNA - BEWO [nTPM]":"92.7","Cell RNA - BJ [nTPM]":"140.0","Cell RNA - BJ hTERT+ [nTPM]":"208.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"90.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"129.2","Cell RNA - CACO-2 [nTPM]":"58.7","Cell RNA - CAPAN-2 [nTPM]":"127.5","Cell RNA - Daudi [nTPM]":"114.7","Cell RNA - EFO-21 [nTPM]":"147.6","Cell RNA - fHDF\/TERT166 [nTPM]":"206.6","Cell RNA - GAMG [nTPM]":"105.3","Cell RNA - HaCaT [nTPM]":"82.5","Cell RNA - HAP1 [nTPM]":"59.6","Cell RNA - HBEC3-KT [nTPM]":"131.0","Cell RNA - HBF TERT88 [nTPM]":"136.5","Cell RNA - HDLM-2 [nTPM]":"168.2","Cell RNA - HEK 293 [nTPM]":"86.4","Cell RNA - HEL [nTPM]":"123.4","Cell RNA - HeLa [nTPM]":"88.8","Cell RNA - Hep G2 [nTPM]":"122.1","Cell RNA - HHSteC [nTPM]":"182.0","Cell RNA - HL-60 [nTPM]":"179.9","Cell RNA - HMC-1 [nTPM]":"197.5","Cell RNA - HSkMC [nTPM]":"190.2","Cell RNA - hTCEpi [nTPM]":"175.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"107.1","Cell RNA - hTERT-HME1 [nTPM]":"52.9","Cell RNA - hTERT-RPE1 [nTPM]":"196.2","Cell RNA - HUVEC TERT2 [nTPM]":"260.0","Cell RNA - JURKAT [nTPM]":"132.6","Cell RNA - K-562 [nTPM]":"111.5","Cell RNA - Karpas-707 [nTPM]":"58.2","Cell RNA - LHCN-M2 [nTPM]":"184.7","Cell RNA - MCF7 [nTPM]":"70.1","Cell RNA - MOLT-4 [nTPM]":"200.7","Cell RNA - NB-4 [nTPM]":"155.2","Cell RNA - NTERA-2 [nTPM]":"94.6","Cell RNA - OE19 [nTPM]":"304.4","Cell RNA - PC-3 [nTPM]":"126.0","Cell RNA - REH [nTPM]":"101.9","Cell RNA - RH-30 [nTPM]":"150.9","Cell RNA - RPMI-8226 [nTPM]":"158.3","Cell RNA - RPTEC TERT1 [nTPM]":"252.2","Cell RNA - RT4 [nTPM]":"192.2","Cell RNA - SCLC-21H [nTPM]":"70.9","Cell RNA - SH-SY5Y [nTPM]":"85.3","Cell RNA - SiHa [nTPM]":"122.0","Cell RNA - SK-BR-3 [nTPM]":"246.3","Cell RNA - SK-MEL-30 [nTPM]":"121.6","Cell RNA - SuSa [nTPM]":"189.6","Cell RNA - T-47d [nTPM]":"125.9","Cell RNA - THP-1 [nTPM]":"201.4","Cell RNA - TIME [nTPM]":"203.8","Cell RNA - U-138 MG [nTPM]":"122.4","Cell RNA - U-2 OS [nTPM]":"63.4","Cell RNA - U-2197 [nTPM]":"213.2","Cell RNA - U-251 MG [nTPM]":"114.9","Cell RNA - U-266\/70 [nTPM]":"95.9","Cell RNA - U-266\/84 [nTPM]":"131.0","Cell RNA - U-698 [nTPM]":"134.2","Cell RNA - U-87 MG [nTPM]":"159.0","Cell RNA - U-937 [nTPM]":"175.7","Cell RNA - WM-115 [nTPM]":"113.8","Blood RNA - basophil [nTPM]":"285.6","Blood RNA - classical monocyte [nTPM]":"193.7","Blood RNA - eosinophil [nTPM]":"286.0","Blood RNA - gdT-cell [nTPM]":"185.9","Blood RNA - intermediate monocyte [nTPM]":"208.8","Blood RNA - MAIT T-cell [nTPM]":"152.1","Blood RNA - memory B-cell [nTPM]":"150.8","Blood RNA - memory CD4 T-cell [nTPM]":"144.9","Blood RNA - memory CD8 T-cell [nTPM]":"184.6","Blood RNA - myeloid DC [nTPM]":"230.5","Blood RNA - naive B-cell [nTPM]":"132.6","Blood RNA - naive CD4 T-cell [nTPM]":"120.8","Blood RNA - naive CD8 T-cell [nTPM]":"171.4","Blood RNA - neutrophil [nTPM]":"29.4","Blood RNA - NK-cell [nTPM]":"176.8","Blood RNA - non-classical monocyte [nTPM]":"204.2","Blood RNA - plasmacytoid DC [nTPM]":"150.9","Blood RNA - T-reg [nTPM]":"195.2","Blood RNA - total PBMC [nTPM]":"289.5","Brain RNA - amygdala [nTPM]":"68.5","Brain RNA - basal ganglia [nTPM]":"71.6","Brain RNA - cerebellum [nTPM]":"74.2","Brain RNA - cerebral cortex [nTPM]":"90.1","Brain RNA - hippocampal formation [nTPM]":"65.8","Brain RNA - hypothalamus [nTPM]":"76.1","Brain RNA - medulla oblongata [nTPM]":"75.4","Brain RNA - midbrain [nTPM]":"72.3","Brain RNA - pons [nTPM]":"77.9","Brain RNA - spinal cord [nTPM]":"75.6","Brain RNA - thalamus [nTPM]":"74.7","Brain RNA - white matter [nTPM]":"78.9","Single Cell Type RNA - Adipocytes [nTPM]":"167.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"134.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"198.4","Single Cell Type RNA - Astrocytes [nTPM]":"52.2","Single Cell Type RNA - B-cells [nTPM]":"91.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"150.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"123.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"222.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"110.4","Single Cell Type RNA - Bipolar cells [nTPM]":"37.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"189.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"86.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"157.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"258.7","Single Cell Type RNA - Club cells [nTPM]":"166.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"185.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"182.7","Single Cell Type RNA - dendritic cells [nTPM]":"128.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"512.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"473.5","Single Cell Type RNA - Ductal cells [nTPM]":"168.1","Single Cell Type RNA - Early spermatids [nTPM]":"57.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"150.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"81.6","Single Cell Type RNA - Endothelial cells [nTPM]":"126.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"235.1","Single Cell Type RNA - Erythroid cells [nTPM]":"93.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"45.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"162.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"156.5","Single Cell Type RNA - Fibroblasts [nTPM]":"124.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"180.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"125.3","Single Cell Type RNA - granulocytes [nTPM]":"138.4","Single Cell Type RNA - Granulosa cells [nTPM]":"54.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"146.7","Single Cell Type RNA - Hepatocytes [nTPM]":"1240.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"203.5","Single Cell Type RNA - Horizontal cells [nTPM]":"42.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"54.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"462.7","Single Cell Type RNA - Ionocytes [nTPM]":"250.3","Single Cell Type RNA - Kupffer cells [nTPM]":"230.1","Single Cell Type RNA - Langerhans cells [nTPM]":"173.1","Single Cell Type RNA - Late spermatids [nTPM]":"51.4","Single Cell Type RNA - Leydig cells [nTPM]":"184.2","Single Cell Type RNA - Macrophages [nTPM]":"148.8","Single Cell Type RNA - Melanocytes [nTPM]":"192.1","Single Cell Type RNA - Microglial cells [nTPM]":"42.2","Single Cell Type RNA - monocytes [nTPM]":"154.6","Single Cell Type RNA - Muller glia cells [nTPM]":"132.0","Single Cell Type RNA - NK-cells [nTPM]":"181.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"48.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"44.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"157.4","Single Cell Type RNA - Paneth cells [nTPM]":"503.4","Single Cell Type RNA - Peritubular cells [nTPM]":"171.9","Single Cell Type RNA - Plasma cells [nTPM]":"76.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"118.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"769.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"881.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"178.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"34.1","Single Cell Type RNA - Sertoli cells [nTPM]":"78.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"72.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"110.6","Single Cell Type RNA - Spermatocytes [nTPM]":"20.4","Single Cell Type RNA - Spermatogonia [nTPM]":"19.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"150.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"170.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"133.9","Single Cell Type RNA - T-cells [nTPM]":"132.9","Single Cell Type RNA - Theca cells [nTPM]":"110.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"336.4","Single Cell Type RNA - Urothelial cells [nTPM]":"187.8"},{"Gene":"SCYL1","Gene synonym":["GKLP","HT019","MGC78454","NKTL","NTKL","P105","TAPK","TEIF","TRAP"],"Ensembl":"ENSG00000142186","Gene description":"SCY1 like pseudokinase 1","Uniprot":["Q96KG9"],"Chromosome":"11","Position":"65525077-65538704","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["ER-Golgi transport","Transcription","Transcription regulation","Transport"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Mental retardation","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"138.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015015"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA015015":"AB_1856643"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.49e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-3"},"Tissue RNA - adipose tissue [nTPM]":"43.4","Tissue RNA - adrenal gland [nTPM]":"69.3","Tissue RNA - amygdala [nTPM]":"36.6","Tissue RNA - appendix [nTPM]":"26.4","Tissue RNA - basal ganglia [nTPM]":"37.4","Tissue RNA - bone marrow [nTPM]":"32.8","Tissue RNA - breast [nTPM]":"41.1","Tissue RNA - cerebellum [nTPM]":"33.1","Tissue RNA - cerebral cortex [nTPM]":"53.9","Tissue RNA - cervix [nTPM]":"46.8","Tissue RNA - choroid plexus [nTPM]":"37.1","Tissue RNA - colon [nTPM]":"46.7","Tissue RNA - duodenum [nTPM]":"28.0","Tissue RNA - endometrium 1 [nTPM]":"49.4","Tissue RNA - epididymis [nTPM]":"32.5","Tissue RNA - esophagus [nTPM]":"40.0","Tissue RNA - fallopian tube [nTPM]":"44.0","Tissue RNA - gallbladder [nTPM]":"26.3","Tissue RNA - heart muscle [nTPM]":"59.7","Tissue RNA - hippocampal formation [nTPM]":"39.2","Tissue RNA - hypothalamus [nTPM]":"34.1","Tissue RNA - kidney [nTPM]":"45.7","Tissue RNA - liver [nTPM]":"83.2","Tissue RNA - lung [nTPM]":"42.4","Tissue RNA - lymph node [nTPM]":"30.7","Tissue RNA - medulla oblongata [nTPM]":"36.0","Tissue RNA - midbrain [nTPM]":"35.2","Tissue RNA - ovary [nTPM]":"52.4","Tissue RNA - pancreas [nTPM]":"61.6","Tissue RNA - parathyroid gland [nTPM]":"35.5","Tissue RNA - pituitary gland [nTPM]":"44.7","Tissue RNA - placenta [nTPM]":"34.6","Tissue RNA - pons [nTPM]":"35.5","Tissue RNA - prostate [nTPM]":"47.3","Tissue RNA - rectum [nTPM]":"17.2","Tissue RNA - retina [nTPM]":"12.4","Tissue RNA - salivary gland [nTPM]":"48.5","Tissue RNA - seminal vesicle [nTPM]":"33.7","Tissue RNA - skeletal muscle [nTPM]":"104.5","Tissue RNA - skin 1 [nTPM]":"44.5","Tissue RNA - small intestine [nTPM]":"39.6","Tissue RNA - smooth muscle [nTPM]":"27.5","Tissue RNA - spinal cord [nTPM]":"30.9","Tissue RNA - spleen [nTPM]":"46.4","Tissue RNA - stomach 1 [nTPM]":"50.0","Tissue RNA - testis [nTPM]":"50.6","Tissue RNA - thalamus [nTPM]":"37.7","Tissue RNA - thymus [nTPM]":"23.4","Tissue RNA - thyroid gland [nTPM]":"48.8","Tissue RNA - tongue [nTPM]":"51.6","Tissue RNA - tonsil [nTPM]":"21.8","Tissue RNA - urinary bladder [nTPM]":"47.8","Tissue RNA - vagina [nTPM]":"39.5","Tissue RNA - white matter [nTPM]":"39.0","Cell RNA - A-431 [nTPM]":"55.0","Cell RNA - A549 [nTPM]":"45.9","Cell RNA - AF22 [nTPM]":"36.6","Cell RNA - AN3-CA [nTPM]":"50.9","Cell RNA - ASC diff [nTPM]":"65.4","Cell RNA - ASC TERT1 [nTPM]":"56.6","Cell RNA - BEWO [nTPM]":"50.0","Cell RNA - BJ [nTPM]":"66.6","Cell RNA - BJ hTERT+ [nTPM]":"89.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"77.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"60.4","Cell RNA - CACO-2 [nTPM]":"66.9","Cell RNA - CAPAN-2 [nTPM]":"32.2","Cell RNA - Daudi [nTPM]":"39.2","Cell RNA - EFO-21 [nTPM]":"65.7","Cell RNA - fHDF\/TERT166 [nTPM]":"86.9","Cell RNA - GAMG [nTPM]":"66.2","Cell RNA - HaCaT [nTPM]":"49.1","Cell RNA - HAP1 [nTPM]":"38.7","Cell RNA - HBEC3-KT [nTPM]":"50.1","Cell RNA - HBF TERT88 [nTPM]":"27.0","Cell RNA - HDLM-2 [nTPM]":"46.6","Cell RNA - HEK 293 [nTPM]":"49.7","Cell RNA - HEL [nTPM]":"46.4","Cell RNA - HeLa [nTPM]":"50.8","Cell RNA - Hep G2 [nTPM]":"78.3","Cell RNA - HHSteC [nTPM]":"92.8","Cell RNA - HL-60 [nTPM]":"30.8","Cell RNA - HMC-1 [nTPM]":"64.0","Cell RNA - HSkMC [nTPM]":"79.1","Cell RNA - hTCEpi [nTPM]":"48.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"66.9","Cell RNA - hTERT-HME1 [nTPM]":"49.4","Cell RNA - hTERT-RPE1 [nTPM]":"54.2","Cell RNA - HUVEC TERT2 [nTPM]":"51.6","Cell RNA - JURKAT [nTPM]":"39.7","Cell RNA - K-562 [nTPM]":"49.2","Cell RNA - Karpas-707 [nTPM]":"53.8","Cell RNA - LHCN-M2 [nTPM]":"49.0","Cell RNA - MCF7 [nTPM]":"118.9","Cell RNA - MOLT-4 [nTPM]":"41.4","Cell RNA - NB-4 [nTPM]":"70.4","Cell RNA - NTERA-2 [nTPM]":"35.3","Cell RNA - OE19 [nTPM]":"36.9","Cell RNA - PC-3 [nTPM]":"63.4","Cell RNA - REH [nTPM]":"41.4","Cell RNA - RH-30 [nTPM]":"28.5","Cell RNA - RPMI-8226 [nTPM]":"72.5","Cell RNA - RPTEC TERT1 [nTPM]":"48.1","Cell RNA - RT4 [nTPM]":"48.4","Cell RNA - SCLC-21H [nTPM]":"33.7","Cell RNA - SH-SY5Y [nTPM]":"35.7","Cell RNA - SiHa [nTPM]":"41.2","Cell RNA - SK-BR-3 [nTPM]":"89.6","Cell RNA - SK-MEL-30 [nTPM]":"74.5","Cell RNA - SuSa [nTPM]":"22.4","Cell RNA - T-47d [nTPM]":"88.8","Cell RNA - THP-1 [nTPM]":"38.4","Cell RNA - TIME [nTPM]":"51.4","Cell RNA - U-138 MG [nTPM]":"61.3","Cell RNA - U-2 OS [nTPM]":"41.0","Cell RNA - U-2197 [nTPM]":"100.7","Cell RNA - U-251 MG [nTPM]":"40.1","Cell RNA - U-266\/70 [nTPM]":"73.8","Cell RNA - U-266\/84 [nTPM]":"55.8","Cell RNA - U-698 [nTPM]":"41.4","Cell RNA - U-87 MG [nTPM]":"71.0","Cell RNA - U-937 [nTPM]":"25.3","Cell RNA - WM-115 [nTPM]":"43.7","Blood RNA - basophil [nTPM]":"2.9","Blood RNA - classical monocyte [nTPM]":"21.1","Blood RNA - eosinophil [nTPM]":"28.4","Blood RNA - gdT-cell [nTPM]":"20.7","Blood RNA - intermediate monocyte [nTPM]":"20.0","Blood RNA - MAIT T-cell [nTPM]":"16.6","Blood RNA - memory B-cell [nTPM]":"14.0","Blood RNA - memory CD4 T-cell [nTPM]":"19.6","Blood RNA - memory CD8 T-cell [nTPM]":"20.9","Blood RNA - myeloid DC [nTPM]":"23.5","Blood RNA - naive B-cell [nTPM]":"14.3","Blood RNA - naive CD4 T-cell [nTPM]":"15.2","Blood RNA - naive CD8 T-cell [nTPM]":"15.0","Blood RNA - neutrophil [nTPM]":"41.9","Blood RNA - NK-cell [nTPM]":"18.2","Blood RNA - non-classical monocyte [nTPM]":"13.6","Blood RNA - plasmacytoid DC [nTPM]":"17.0","Blood RNA - T-reg [nTPM]":"14.4","Blood RNA - total PBMC [nTPM]":"19.8","Brain RNA - amygdala [nTPM]":"36.6","Brain RNA - basal ganglia [nTPM]":"37.4","Brain RNA - cerebellum [nTPM]":"33.1","Brain RNA - cerebral cortex [nTPM]":"53.9","Brain RNA - hippocampal formation [nTPM]":"39.2","Brain RNA - hypothalamus [nTPM]":"34.1","Brain RNA - medulla oblongata [nTPM]":"36.0","Brain RNA - midbrain [nTPM]":"35.2","Brain RNA - pons [nTPM]":"35.5","Brain RNA - spinal cord [nTPM]":"30.9","Brain RNA - thalamus [nTPM]":"37.7","Brain RNA - white matter [nTPM]":"39.0","Single Cell Type RNA - Adipocytes [nTPM]":"22.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.7","Single Cell Type RNA - Astrocytes [nTPM]":"11.4","Single Cell Type RNA - B-cells [nTPM]":"25.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"21.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"29.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.0","Single Cell Type RNA - Bipolar cells [nTPM]":"25.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"26.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"64.6","Single Cell Type RNA - dendritic cells [nTPM]":"18.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"47.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"37.2","Single Cell Type RNA - Ductal cells [nTPM]":"37.5","Single Cell Type RNA - Early spermatids [nTPM]":"25.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.7","Single Cell Type RNA - Endothelial cells [nTPM]":"23.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"30.5","Single Cell Type RNA - Erythroid cells [nTPM]":"22.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"43.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"70.0","Single Cell Type RNA - Fibroblasts [nTPM]":"34.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"38.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.4","Single Cell Type RNA - granulocytes [nTPM]":"25.4","Single Cell Type RNA - Granulosa cells [nTPM]":"34.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.1","Single Cell Type RNA - Hepatocytes [nTPM]":"35.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"38.1","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"39.9","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"19.2","Single Cell Type RNA - Langerhans cells [nTPM]":"24.3","Single Cell Type RNA - Late spermatids [nTPM]":"25.2","Single Cell Type RNA - Leydig cells [nTPM]":"45.7","Single Cell Type RNA - Macrophages [nTPM]":"24.5","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"34.3","Single Cell Type RNA - Muller glia cells [nTPM]":"26.6","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"36.4","Single Cell Type RNA - Paneth cells [nTPM]":"31.4","Single Cell Type RNA - Peritubular cells [nTPM]":"45.5","Single Cell Type RNA - Plasma cells [nTPM]":"53.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"44.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"50.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"37.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"22.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"24.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"33.8","Single Cell Type RNA - Spermatocytes [nTPM]":"39.5","Single Cell Type RNA - Spermatogonia [nTPM]":"21.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"27.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"23.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"138.6","Single Cell Type RNA - T-cells [nTPM]":"23.2","Single Cell Type RNA - Theca cells [nTPM]":"44.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"36.2","Single Cell Type RNA - Urothelial cells [nTPM]":"38.5"},{"Gene":"SCYL2","Gene synonym":["CVAK104","KIAA1360"],"Ensembl":"ENSG00000136021","Gene description":"SCY1 like pseudokinase 2","Uniprot":["Q6P3W7"],"Chromosome":"12","Position":"100267140-100341715","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021050"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA021050":"AB_1846175"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Tissue RNA - adipose tissue [nTPM]":"13.4","Tissue RNA - adrenal gland [nTPM]":"13.4","Tissue RNA - amygdala [nTPM]":"6.2","Tissue RNA - appendix [nTPM]":"16.4","Tissue RNA - basal ganglia [nTPM]":"7.3","Tissue RNA - bone marrow [nTPM]":"21.5","Tissue RNA - breast [nTPM]":"16.8","Tissue RNA - cerebellum [nTPM]":"9.9","Tissue RNA - cerebral cortex [nTPM]":"8.2","Tissue RNA - cervix [nTPM]":"14.0","Tissue RNA - choroid plexus [nTPM]":"7.6","Tissue RNA - colon [nTPM]":"22.9","Tissue RNA - duodenum [nTPM]":"20.2","Tissue RNA - endometrium 1 [nTPM]":"14.5","Tissue RNA - epididymis [nTPM]":"20.9","Tissue RNA - esophagus [nTPM]":"22.1","Tissue RNA - fallopian tube [nTPM]":"10.9","Tissue RNA - gallbladder [nTPM]":"16.2","Tissue RNA - heart muscle [nTPM]":"14.9","Tissue RNA - hippocampal formation [nTPM]":"7.6","Tissue RNA - hypothalamus [nTPM]":"8.6","Tissue RNA - kidney [nTPM]":"21.2","Tissue RNA - liver [nTPM]":"28.7","Tissue RNA - lung [nTPM]":"17.2","Tissue RNA - lymph node [nTPM]":"15.0","Tissue RNA - medulla oblongata [nTPM]":"5.6","Tissue RNA - midbrain [nTPM]":"5.4","Tissue RNA - ovary [nTPM]":"8.8","Tissue RNA - pancreas [nTPM]":"17.9","Tissue RNA - parathyroid gland [nTPM]":"20.9","Tissue RNA - pituitary gland [nTPM]":"12.9","Tissue RNA - placenta [nTPM]":"21.0","Tissue RNA - pons [nTPM]":"6.3","Tissue RNA - prostate [nTPM]":"17.0","Tissue RNA - rectum [nTPM]":"26.9","Tissue RNA - retina [nTPM]":"16.7","Tissue RNA - salivary gland [nTPM]":"15.7","Tissue RNA - seminal vesicle [nTPM]":"15.9","Tissue RNA - skeletal muscle [nTPM]":"15.6","Tissue RNA - skin 1 [nTPM]":"13.7","Tissue RNA - small intestine [nTPM]":"17.0","Tissue RNA - smooth muscle [nTPM]":"17.4","Tissue RNA - spinal cord [nTPM]":"6.3","Tissue RNA - spleen [nTPM]":"14.7","Tissue RNA - stomach 1 [nTPM]":"16.4","Tissue RNA - testis [nTPM]":"14.6","Tissue RNA - thalamus [nTPM]":"7.5","Tissue RNA - thymus [nTPM]":"19.0","Tissue RNA - thyroid gland [nTPM]":"15.6","Tissue RNA - tongue [nTPM]":"19.1","Tissue RNA - tonsil [nTPM]":"19.8","Tissue RNA - urinary bladder [nTPM]":"21.5","Tissue RNA - vagina [nTPM]":"11.5","Tissue RNA - white matter [nTPM]":"7.2","Cell RNA - A-431 [nTPM]":"37.7","Cell RNA - A549 [nTPM]":"29.0","Cell RNA - AF22 [nTPM]":"45.8","Cell RNA - AN3-CA [nTPM]":"37.7","Cell RNA - ASC diff [nTPM]":"28.8","Cell RNA - ASC TERT1 [nTPM]":"31.1","Cell RNA - BEWO [nTPM]":"43.2","Cell RNA - BJ [nTPM]":"38.0","Cell RNA - BJ hTERT+ [nTPM]":"42.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"34.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"29.6","Cell RNA - CACO-2 [nTPM]":"28.1","Cell RNA - CAPAN-2 [nTPM]":"19.4","Cell RNA - Daudi [nTPM]":"23.4","Cell RNA - EFO-21 [nTPM]":"17.7","Cell RNA - fHDF\/TERT166 [nTPM]":"46.9","Cell RNA - GAMG [nTPM]":"23.7","Cell RNA - HaCaT [nTPM]":"32.1","Cell RNA - HAP1 [nTPM]":"36.4","Cell RNA - HBEC3-KT [nTPM]":"27.8","Cell RNA - HBF TERT88 [nTPM]":"40.6","Cell RNA - HDLM-2 [nTPM]":"36.5","Cell RNA - HEK 293 [nTPM]":"24.2","Cell RNA - HEL [nTPM]":"76.0","Cell RNA - HeLa [nTPM]":"18.5","Cell RNA - Hep G2 [nTPM]":"20.3","Cell RNA - HHSteC [nTPM]":"25.7","Cell RNA - HL-60 [nTPM]":"36.2","Cell RNA - HMC-1 [nTPM]":"72.8","Cell RNA - HSkMC [nTPM]":"23.1","Cell RNA - hTCEpi [nTPM]":"42.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"39.5","Cell RNA - hTERT-HME1 [nTPM]":"44.9","Cell RNA - hTERT-RPE1 [nTPM]":"41.3","Cell RNA - HUVEC TERT2 [nTPM]":"44.4","Cell RNA - JURKAT [nTPM]":"26.0","Cell RNA - K-562 [nTPM]":"40.8","Cell RNA - Karpas-707 [nTPM]":"19.7","Cell RNA - LHCN-M2 [nTPM]":"37.4","Cell RNA - MCF7 [nTPM]":"29.2","Cell RNA - MOLT-4 [nTPM]":"29.2","Cell RNA - NB-4 [nTPM]":"31.7","Cell RNA - NTERA-2 [nTPM]":"28.6","Cell RNA - OE19 [nTPM]":"21.7","Cell RNA - PC-3 [nTPM]":"32.6","Cell RNA - REH [nTPM]":"23.4","Cell RNA - RH-30 [nTPM]":"33.6","Cell RNA - RPMI-8226 [nTPM]":"22.7","Cell RNA - RPTEC TERT1 [nTPM]":"31.6","Cell RNA - RT4 [nTPM]":"61.1","Cell RNA - SCLC-21H [nTPM]":"28.3","Cell RNA - SH-SY5Y [nTPM]":"25.3","Cell RNA - SiHa [nTPM]":"43.0","Cell RNA - SK-BR-3 [nTPM]":"44.2","Cell RNA - SK-MEL-30 [nTPM]":"36.2","Cell RNA - SuSa [nTPM]":"48.2","Cell RNA - T-47d [nTPM]":"64.9","Cell RNA - THP-1 [nTPM]":"27.8","Cell RNA - TIME [nTPM]":"41.7","Cell RNA - U-138 MG [nTPM]":"29.7","Cell RNA - U-2 OS [nTPM]":"17.2","Cell RNA - U-2197 [nTPM]":"27.8","Cell RNA - U-251 MG [nTPM]":"24.8","Cell RNA - U-266\/70 [nTPM]":"22.6","Cell RNA - U-266\/84 [nTPM]":"32.1","Cell RNA - U-698 [nTPM]":"28.3","Cell RNA - U-87 MG [nTPM]":"14.6","Cell RNA - U-937 [nTPM]":"24.6","Cell RNA - WM-115 [nTPM]":"34.4","Blood RNA - basophil [nTPM]":"12.3","Blood RNA - classical monocyte [nTPM]":"5.2","Blood RNA - eosinophil [nTPM]":"10.0","Blood RNA - gdT-cell [nTPM]":"4.0","Blood RNA - intermediate monocyte [nTPM]":"6.5","Blood RNA - MAIT T-cell [nTPM]":"5.1","Blood RNA - memory B-cell [nTPM]":"3.3","Blood RNA - memory CD4 T-cell [nTPM]":"4.2","Blood RNA - memory CD8 T-cell [nTPM]":"3.8","Blood RNA - myeloid DC [nTPM]":"6.6","Blood RNA - naive B-cell [nTPM]":"2.3","Blood RNA - naive CD4 T-cell [nTPM]":"4.5","Blood RNA - naive CD8 T-cell [nTPM]":"4.9","Blood RNA - neutrophil [nTPM]":"6.7","Blood RNA - NK-cell [nTPM]":"8.6","Blood RNA - non-classical monocyte [nTPM]":"5.7","Blood RNA - plasmacytoid DC [nTPM]":"2.0","Blood RNA - T-reg [nTPM]":"6.2","Blood RNA - total PBMC [nTPM]":"4.0","Brain RNA - amygdala [nTPM]":"6.2","Brain RNA - basal ganglia [nTPM]":"7.3","Brain RNA - cerebellum [nTPM]":"9.9","Brain RNA - cerebral cortex [nTPM]":"8.2","Brain RNA - hippocampal formation [nTPM]":"7.6","Brain RNA - hypothalamus [nTPM]":"8.6","Brain RNA - medulla oblongata [nTPM]":"5.6","Brain RNA - midbrain [nTPM]":"5.4","Brain RNA - pons [nTPM]":"6.3","Brain RNA - spinal cord [nTPM]":"6.3","Brain RNA - thalamus [nTPM]":"7.5","Brain RNA - white matter [nTPM]":"7.2","Single Cell Type RNA - Adipocytes [nTPM]":"24.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"35.2","Single Cell Type RNA - Astrocytes [nTPM]":"37.9","Single Cell Type RNA - B-cells [nTPM]":"20.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"35.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"33.0","Single Cell Type RNA - Bipolar cells [nTPM]":"16.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"30.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"26.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"31.3","Single Cell Type RNA - dendritic cells [nTPM]":"22.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"16.8","Single Cell Type RNA - Early spermatids [nTPM]":"8.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"24.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.1","Single Cell Type RNA - Endothelial cells [nTPM]":"24.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.7","Single Cell Type RNA - Erythroid cells [nTPM]":"28.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"50.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"22.2","Single Cell Type RNA - Fibroblasts [nTPM]":"20.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"37.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"31.2","Single Cell Type RNA - granulocytes [nTPM]":"27.9","Single Cell Type RNA - Granulosa cells [nTPM]":"15.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.4","Single Cell Type RNA - Hepatocytes [nTPM]":"37.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.1","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"54.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"30.6","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"34.6","Single Cell Type RNA - Langerhans cells [nTPM]":"47.4","Single Cell Type RNA - Late spermatids [nTPM]":"4.7","Single Cell Type RNA - Leydig cells [nTPM]":"13.4","Single Cell Type RNA - Macrophages [nTPM]":"29.2","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"44.0","Single Cell Type RNA - monocytes [nTPM]":"27.5","Single Cell Type RNA - Muller glia cells [nTPM]":"10.9","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"64.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"47.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"24.0","Single Cell Type RNA - Paneth cells [nTPM]":"32.1","Single Cell Type RNA - Peritubular cells [nTPM]":"15.4","Single Cell Type RNA - Plasma cells [nTPM]":"22.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"36.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"16.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"26.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.9","Single Cell Type RNA - Spermatocytes [nTPM]":"24.9","Single Cell Type RNA - Spermatogonia [nTPM]":"12.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"36.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"34.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"59.4","Single Cell Type RNA - T-cells [nTPM]":"22.6","Single Cell Type RNA - Theca cells [nTPM]":"19.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"33.6","Single Cell Type RNA - Urothelial cells [nTPM]":"52.8"},{"Gene":"SDHB","Gene synonym":["SDH","SDH1"],"Ensembl":"ENSG00000117118","Gene description":"Succinate dehydrogenase complex iron sulfur subunit B","Uniprot":["P21912"],"Chromosome":"1","Position":"17018722-17054032","Protein class":["Cancer-related genes","Citric acid cycle related proteins","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Electron transport","Transport","Tricarboxylic acid cycle"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"491.5","tongue":"580.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"405.5","Proximal tubular cells":"449.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002868","CAB009822","CAB068233","CAB068234","CAB068235"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Mitochondria"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7900","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm","Plasma membrane"],"Antibody RRID":{"CAB009822":"AB_2183458","CAB068233":"AB_2665638","CAB068234":"AB_2665639","CAB068235":"AB_2665640","HPA002868":"AB_1079889"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.93e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Tissue RNA - adipose tissue [nTPM]":"85.8","Tissue RNA - adrenal gland [nTPM]":"95.7","Tissue RNA - amygdala [nTPM]":"68.0","Tissue RNA - appendix [nTPM]":"59.0","Tissue RNA - basal ganglia [nTPM]":"72.2","Tissue RNA - bone marrow [nTPM]":"94.6","Tissue RNA - breast [nTPM]":"68.7","Tissue RNA - cerebellum [nTPM]":"80.6","Tissue RNA - cerebral cortex [nTPM]":"84.3","Tissue RNA - cervix [nTPM]":"56.8","Tissue RNA - choroid plexus [nTPM]":"81.1","Tissue RNA - colon [nTPM]":"134.3","Tissue RNA - duodenum [nTPM]":"163.0","Tissue RNA - endometrium 1 [nTPM]":"56.0","Tissue RNA - epididymis [nTPM]":"71.0","Tissue RNA - esophagus [nTPM]":"77.4","Tissue RNA - fallopian tube [nTPM]":"59.8","Tissue RNA - gallbladder [nTPM]":"48.0","Tissue RNA - heart muscle [nTPM]":"302.8","Tissue RNA - hippocampal formation [nTPM]":"69.9","Tissue RNA - hypothalamus [nTPM]":"76.9","Tissue RNA - kidney [nTPM]":"228.0","Tissue RNA - liver [nTPM]":"336.1","Tissue RNA - lung [nTPM]":"56.1","Tissue RNA - lymph node [nTPM]":"75.3","Tissue RNA - medulla oblongata [nTPM]":"74.8","Tissue RNA - midbrain [nTPM]":"71.4","Tissue RNA - ovary [nTPM]":"44.4","Tissue RNA - pancreas [nTPM]":"80.3","Tissue RNA - parathyroid gland [nTPM]":"144.3","Tissue RNA - pituitary gland [nTPM]":"42.8","Tissue RNA - placenta [nTPM]":"57.6","Tissue RNA - pons [nTPM]":"73.8","Tissue RNA - prostate [nTPM]":"55.7","Tissue RNA - rectum [nTPM]":"132.4","Tissue RNA - retina [nTPM]":"62.9","Tissue RNA - salivary gland [nTPM]":"74.0","Tissue RNA - seminal vesicle [nTPM]":"60.5","Tissue RNA - skeletal muscle [nTPM]":"491.5","Tissue RNA - skin 1 [nTPM]":"55.6","Tissue RNA - small intestine [nTPM]":"121.9","Tissue RNA - smooth muscle [nTPM]":"70.4","Tissue RNA - spinal cord [nTPM]":"73.9","Tissue RNA - spleen [nTPM]":"60.5","Tissue RNA - stomach 1 [nTPM]":"92.8","Tissue RNA - testis [nTPM]":"64.4","Tissue RNA - thalamus [nTPM]":"74.9","Tissue RNA - thymus [nTPM]":"62.7","Tissue RNA - thyroid gland [nTPM]":"64.3","Tissue RNA - tongue [nTPM]":"580.6","Tissue RNA - tonsil [nTPM]":"84.2","Tissue RNA - urinary bladder [nTPM]":"71.3","Tissue RNA - vagina [nTPM]":"52.0","Tissue RNA - white matter [nTPM]":"78.9","Cell RNA - A-431 [nTPM]":"157.3","Cell RNA - A549 [nTPM]":"152.7","Cell RNA - AF22 [nTPM]":"72.2","Cell RNA - AN3-CA [nTPM]":"107.8","Cell RNA - ASC diff [nTPM]":"141.6","Cell RNA - ASC TERT1 [nTPM]":"135.2","Cell RNA - BEWO [nTPM]":"95.9","Cell RNA - BJ [nTPM]":"122.4","Cell RNA - BJ hTERT+ [nTPM]":"145.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"254.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"227.7","Cell RNA - CACO-2 [nTPM]":"216.8","Cell RNA - CAPAN-2 [nTPM]":"183.1","Cell RNA - Daudi [nTPM]":"206.8","Cell RNA - EFO-21 [nTPM]":"159.3","Cell RNA - fHDF\/TERT166 [nTPM]":"156.4","Cell RNA - GAMG [nTPM]":"176.1","Cell RNA - HaCaT [nTPM]":"180.1","Cell RNA - HAP1 [nTPM]":"290.7","Cell RNA - HBEC3-KT [nTPM]":"226.8","Cell RNA - HBF TERT88 [nTPM]":"284.8","Cell RNA - HDLM-2 [nTPM]":"128.7","Cell RNA - HEK 293 [nTPM]":"280.6","Cell RNA - HEL [nTPM]":"183.4","Cell RNA - HeLa [nTPM]":"149.2","Cell RNA - Hep G2 [nTPM]":"168.2","Cell RNA - HHSteC [nTPM]":"172.8","Cell RNA - HL-60 [nTPM]":"276.0","Cell RNA - HMC-1 [nTPM]":"135.6","Cell RNA - HSkMC [nTPM]":"140.4","Cell RNA - hTCEpi [nTPM]":"154.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"224.5","Cell RNA - hTERT-HME1 [nTPM]":"370.1","Cell RNA - hTERT-RPE1 [nTPM]":"138.7","Cell RNA - HUVEC TERT2 [nTPM]":"183.6","Cell RNA - JURKAT [nTPM]":"176.5","Cell RNA - K-562 [nTPM]":"165.2","Cell RNA - Karpas-707 [nTPM]":"236.9","Cell RNA - LHCN-M2 [nTPM]":"179.6","Cell RNA - MCF7 [nTPM]":"129.5","Cell RNA - MOLT-4 [nTPM]":"182.4","Cell RNA - NB-4 [nTPM]":"175.1","Cell RNA - NTERA-2 [nTPM]":"70.4","Cell RNA - OE19 [nTPM]":"224.6","Cell RNA - PC-3 [nTPM]":"302.6","Cell RNA - REH [nTPM]":"146.1","Cell RNA - RH-30 [nTPM]":"142.5","Cell RNA - RPMI-8226 [nTPM]":"265.4","Cell RNA - RPTEC TERT1 [nTPM]":"252.4","Cell RNA - RT4 [nTPM]":"88.7","Cell RNA - SCLC-21H [nTPM]":"157.5","Cell RNA - SH-SY5Y [nTPM]":"86.0","Cell RNA - SiHa [nTPM]":"172.3","Cell RNA - SK-BR-3 [nTPM]":"216.3","Cell RNA - SK-MEL-30 [nTPM]":"392.3","Cell RNA - SuSa [nTPM]":"76.4","Cell RNA - T-47d [nTPM]":"131.1","Cell RNA - THP-1 [nTPM]":"169.1","Cell RNA - TIME [nTPM]":"94.9","Cell RNA - U-138 MG [nTPM]":"115.8","Cell RNA - U-2 OS [nTPM]":"131.0","Cell RNA - U-2197 [nTPM]":"206.4","Cell RNA - U-251 MG [nTPM]":"176.0","Cell RNA - U-266\/70 [nTPM]":"98.9","Cell RNA - U-266\/84 [nTPM]":"133.3","Cell RNA - U-698 [nTPM]":"198.6","Cell RNA - U-87 MG [nTPM]":"170.4","Cell RNA - U-937 [nTPM]":"438.5","Cell RNA - WM-115 [nTPM]":"128.3","Blood RNA - basophil [nTPM]":"68.7","Blood RNA - classical monocyte [nTPM]":"149.8","Blood RNA - eosinophil [nTPM]":"149.5","Blood RNA - gdT-cell [nTPM]":"71.4","Blood RNA - intermediate monocyte [nTPM]":"206.5","Blood RNA - MAIT T-cell [nTPM]":"70.7","Blood RNA - memory B-cell [nTPM]":"89.9","Blood RNA - memory CD4 T-cell [nTPM]":"81.0","Blood RNA - memory CD8 T-cell [nTPM]":"77.5","Blood RNA - myeloid DC [nTPM]":"186.8","Blood RNA - naive B-cell [nTPM]":"81.1","Blood RNA - naive CD4 T-cell [nTPM]":"73.5","Blood RNA - naive CD8 T-cell [nTPM]":"74.8","Blood RNA - neutrophil [nTPM]":"174.3","Blood RNA - NK-cell [nTPM]":"85.3","Blood RNA - non-classical monocyte [nTPM]":"185.7","Blood RNA - plasmacytoid DC [nTPM]":"89.3","Blood RNA - T-reg [nTPM]":"113.8","Blood RNA - total PBMC [nTPM]":"116.1","Brain RNA - amygdala [nTPM]":"68.0","Brain RNA - basal ganglia [nTPM]":"72.2","Brain RNA - cerebellum [nTPM]":"80.6","Brain RNA - cerebral cortex [nTPM]":"84.3","Brain RNA - hippocampal formation [nTPM]":"69.9","Brain RNA - hypothalamus [nTPM]":"76.9","Brain RNA - medulla oblongata [nTPM]":"74.8","Brain RNA - midbrain [nTPM]":"71.4","Brain RNA - pons [nTPM]":"73.8","Brain RNA - spinal cord [nTPM]":"73.9","Brain RNA - thalamus [nTPM]":"74.9","Brain RNA - white matter [nTPM]":"78.9","Single Cell Type RNA - Adipocytes [nTPM]":"48.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"64.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"47.4","Single Cell Type RNA - Astrocytes [nTPM]":"20.9","Single Cell Type RNA - B-cells [nTPM]":"57.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"52.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"93.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"199.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"40.5","Single Cell Type RNA - Bipolar cells [nTPM]":"31.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"45.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"49.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"405.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"101.5","Single Cell Type RNA - Club cells [nTPM]":"97.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"47.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"107.1","Single Cell Type RNA - dendritic cells [nTPM]":"48.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"176.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"354.1","Single Cell Type RNA - Ductal cells [nTPM]":"134.3","Single Cell Type RNA - Early spermatids [nTPM]":"220.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"48.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"38.2","Single Cell Type RNA - Endothelial cells [nTPM]":"54.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"48.6","Single Cell Type RNA - Erythroid cells [nTPM]":"77.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"27.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"149.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"142.2","Single Cell Type RNA - Fibroblasts [nTPM]":"62.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"46.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"45.5","Single Cell Type RNA - granulocytes [nTPM]":"66.6","Single Cell Type RNA - Granulosa cells [nTPM]":"39.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"46.8","Single Cell Type RNA - Hepatocytes [nTPM]":"226.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"177.4","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"32.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"103.1","Single Cell Type RNA - Ionocytes [nTPM]":"116.0","Single Cell Type RNA - Kupffer cells [nTPM]":"88.7","Single Cell Type RNA - Langerhans cells [nTPM]":"67.9","Single Cell Type RNA - Late spermatids [nTPM]":"30.5","Single Cell Type RNA - Leydig cells [nTPM]":"57.8","Single Cell Type RNA - Macrophages [nTPM]":"78.4","Single Cell Type RNA - Melanocytes [nTPM]":"64.0","Single Cell Type RNA - Microglial cells [nTPM]":"29.0","Single Cell Type RNA - monocytes [nTPM]":"123.1","Single Cell Type RNA - Muller glia cells [nTPM]":"78.3","Single Cell Type RNA - NK-cells [nTPM]":"48.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"24.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"111.5","Single Cell Type RNA - Paneth cells [nTPM]":"218.3","Single Cell Type RNA - Peritubular cells [nTPM]":"67.7","Single Cell Type RNA - Plasma cells [nTPM]":"62.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"74.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"300.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"449.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"79.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"53.8","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"57.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"191.6","Single Cell Type RNA - Spermatocytes [nTPM]":"148.9","Single Cell Type RNA - Spermatogonia [nTPM]":"71.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"72.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"54.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"121.8","Single Cell Type RNA - T-cells [nTPM]":"46.8","Single Cell Type RNA - Theca cells [nTPM]":"69.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"162.0","Single Cell Type RNA - Urothelial cells [nTPM]":"110.9"},{"Gene":"SDHC","Gene synonym":["CYB560","cybL","PGL3"],"Ensembl":"ENSG00000143252","Gene description":"Succinate dehydrogenase complex subunit C","Uniprot":["Q99643"],"Chromosome":"1","Position":"161314381-161363206","Protein class":["Cancer-related genes","Citric acid cycle related proteins","Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Electron transport","Transport","Tricarboxylic acid cycle"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"776.7","Proximal tubular cells":"916.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.20e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Tissue RNA - adipose tissue [nTPM]":"128.9","Tissue RNA - adrenal gland [nTPM]":"143.7","Tissue RNA - amygdala [nTPM]":"73.7","Tissue RNA - appendix [nTPM]":"64.1","Tissue RNA - basal ganglia [nTPM]":"79.7","Tissue RNA - bone marrow [nTPM]":"60.5","Tissue RNA - breast [nTPM]":"100.3","Tissue RNA - cerebellum [nTPM]":"84.5","Tissue RNA - cerebral cortex [nTPM]":"85.1","Tissue RNA - cervix [nTPM]":"78.7","Tissue RNA - choroid plexus [nTPM]":"92.9","Tissue RNA - colon [nTPM]":"118.9","Tissue RNA - duodenum [nTPM]":"127.8","Tissue RNA - endometrium 1 [nTPM]":"70.9","Tissue RNA - epididymis [nTPM]":"76.0","Tissue RNA - esophagus [nTPM]":"109.7","Tissue RNA - fallopian tube [nTPM]":"98.6","Tissue RNA - gallbladder [nTPM]":"63.3","Tissue RNA - heart muscle [nTPM]":"154.1","Tissue RNA - hippocampal formation [nTPM]":"68.4","Tissue RNA - hypothalamus [nTPM]":"83.4","Tissue RNA - kidney [nTPM]":"285.7","Tissue RNA - liver [nTPM]":"319.4","Tissue RNA - lung [nTPM]":"65.5","Tissue RNA - lymph node [nTPM]":"74.7","Tissue RNA - medulla oblongata [nTPM]":"78.8","Tissue RNA - midbrain [nTPM]":"79.1","Tissue RNA - ovary [nTPM]":"69.2","Tissue RNA - pancreas [nTPM]":"62.5","Tissue RNA - parathyroid gland [nTPM]":"173.6","Tissue RNA - pituitary gland [nTPM]":"52.4","Tissue RNA - placenta [nTPM]":"73.1","Tissue RNA - pons [nTPM]":"76.7","Tissue RNA - prostate [nTPM]":"77.3","Tissue RNA - rectum [nTPM]":"132.2","Tissue RNA - retina [nTPM]":"84.3","Tissue RNA - salivary gland [nTPM]":"74.8","Tissue RNA - seminal vesicle [nTPM]":"84.7","Tissue RNA - skeletal muscle [nTPM]":"277.4","Tissue RNA - skin 1 [nTPM]":"69.8","Tissue RNA - small intestine [nTPM]":"101.4","Tissue RNA - smooth muscle [nTPM]":"101.4","Tissue RNA - spinal cord [nTPM]":"85.1","Tissue RNA - spleen [nTPM]":"62.8","Tissue RNA - stomach 1 [nTPM]":"89.9","Tissue RNA - testis [nTPM]":"52.7","Tissue RNA - thalamus [nTPM]":"84.8","Tissue RNA - thymus [nTPM]":"93.1","Tissue RNA - thyroid gland [nTPM]":"89.5","Tissue RNA - tongue [nTPM]":"288.4","Tissue RNA - tonsil [nTPM]":"105.1","Tissue RNA - urinary bladder [nTPM]":"88.4","Tissue RNA - vagina [nTPM]":"61.3","Tissue RNA - white matter [nTPM]":"85.6","Cell RNA - A-431 [nTPM]":"161.1","Cell RNA - A549 [nTPM]":"129.7","Cell RNA - AF22 [nTPM]":"157.5","Cell RNA - AN3-CA [nTPM]":"147.7","Cell RNA - ASC diff [nTPM]":"248.3","Cell RNA - ASC TERT1 [nTPM]":"213.3","Cell RNA - BEWO [nTPM]":"196.3","Cell RNA - BJ [nTPM]":"150.9","Cell RNA - BJ hTERT+ [nTPM]":"190.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"180.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"137.3","Cell RNA - CACO-2 [nTPM]":"185.4","Cell RNA - CAPAN-2 [nTPM]":"208.7","Cell RNA - Daudi [nTPM]":"53.7","Cell RNA - EFO-21 [nTPM]":"190.6","Cell RNA - fHDF\/TERT166 [nTPM]":"214.8","Cell RNA - GAMG [nTPM]":"121.6","Cell RNA - HaCaT [nTPM]":"178.5","Cell RNA - HAP1 [nTPM]":"244.3","Cell RNA - HBEC3-KT [nTPM]":"214.2","Cell RNA - HBF TERT88 [nTPM]":"193.2","Cell RNA - HDLM-2 [nTPM]":"185.6","Cell RNA - HEK 293 [nTPM]":"205.6","Cell RNA - HEL [nTPM]":"110.2","Cell RNA - HeLa [nTPM]":"106.6","Cell RNA - Hep G2 [nTPM]":"196.7","Cell RNA - HHSteC [nTPM]":"126.9","Cell RNA - HL-60 [nTPM]":"193.8","Cell RNA - HMC-1 [nTPM]":"109.1","Cell RNA - HSkMC [nTPM]":"211.5","Cell RNA - hTCEpi [nTPM]":"181.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"174.3","Cell RNA - hTERT-HME1 [nTPM]":"119.4","Cell RNA - hTERT-RPE1 [nTPM]":"167.9","Cell RNA - HUVEC TERT2 [nTPM]":"177.5","Cell RNA - JURKAT [nTPM]":"164.0","Cell RNA - K-562 [nTPM]":"178.9","Cell RNA - Karpas-707 [nTPM]":"43.8","Cell RNA - LHCN-M2 [nTPM]":"266.3","Cell RNA - MCF7 [nTPM]":"167.0","Cell RNA - MOLT-4 [nTPM]":"152.4","Cell RNA - NB-4 [nTPM]":"112.5","Cell RNA - NTERA-2 [nTPM]":"145.4","Cell RNA - OE19 [nTPM]":"376.3","Cell RNA - PC-3 [nTPM]":"123.7","Cell RNA - REH [nTPM]":"131.6","Cell RNA - RH-30 [nTPM]":"151.0","Cell RNA - RPMI-8226 [nTPM]":"217.1","Cell RNA - RPTEC TERT1 [nTPM]":"330.3","Cell RNA - RT4 [nTPM]":"167.8","Cell RNA - SCLC-21H [nTPM]":"118.3","Cell RNA - SH-SY5Y [nTPM]":"180.7","Cell RNA - SiHa [nTPM]":"211.0","Cell RNA - SK-BR-3 [nTPM]":"385.1","Cell RNA - SK-MEL-30 [nTPM]":"225.4","Cell RNA - SuSa [nTPM]":"207.9","Cell RNA - T-47d [nTPM]":"342.1","Cell RNA - THP-1 [nTPM]":"259.3","Cell RNA - TIME [nTPM]":"133.5","Cell RNA - U-138 MG [nTPM]":"103.7","Cell RNA - U-2 OS [nTPM]":"125.1","Cell RNA - U-2197 [nTPM]":"127.9","Cell RNA - U-251 MG [nTPM]":"147.3","Cell RNA - U-266\/70 [nTPM]":"173.3","Cell RNA - U-266\/84 [nTPM]":"287.8","Cell RNA - U-698 [nTPM]":"269.4","Cell RNA - U-87 MG [nTPM]":"140.3","Cell RNA - U-937 [nTPM]":"139.2","Cell RNA - WM-115 [nTPM]":"193.6","Blood RNA - basophil [nTPM]":"88.6","Blood RNA - classical monocyte [nTPM]":"111.0","Blood RNA - eosinophil [nTPM]":"65.7","Blood RNA - gdT-cell [nTPM]":"76.6","Blood RNA - intermediate monocyte [nTPM]":"99.6","Blood RNA - MAIT T-cell [nTPM]":"79.6","Blood RNA - memory B-cell [nTPM]":"68.6","Blood RNA - memory CD4 T-cell [nTPM]":"66.2","Blood RNA - memory CD8 T-cell [nTPM]":"75.4","Blood RNA - myeloid DC [nTPM]":"136.1","Blood RNA - naive B-cell [nTPM]":"65.7","Blood RNA - naive CD4 T-cell [nTPM]":"71.2","Blood RNA - naive CD8 T-cell [nTPM]":"71.0","Blood RNA - neutrophil [nTPM]":"52.0","Blood RNA - NK-cell [nTPM]":"66.9","Blood RNA - non-classical monocyte [nTPM]":"87.5","Blood RNA - plasmacytoid DC [nTPM]":"100.6","Blood RNA - T-reg [nTPM]":"78.3","Blood RNA - total PBMC [nTPM]":"130.0","Brain RNA - amygdala [nTPM]":"73.7","Brain RNA - basal ganglia [nTPM]":"79.7","Brain RNA - cerebellum [nTPM]":"84.5","Brain RNA - cerebral cortex [nTPM]":"85.1","Brain RNA - hippocampal formation [nTPM]":"68.4","Brain RNA - hypothalamus [nTPM]":"83.4","Brain RNA - medulla oblongata [nTPM]":"78.8","Brain RNA - midbrain [nTPM]":"79.1","Brain RNA - pons [nTPM]":"76.7","Brain RNA - spinal cord [nTPM]":"85.1","Brain RNA - thalamus [nTPM]":"84.8","Brain RNA - white matter [nTPM]":"85.6","Single Cell Type RNA - Adipocytes [nTPM]":"50.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"59.4","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"70.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"61.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"151.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"342.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"59.7","Single Cell Type RNA - Bipolar cells [nTPM]":"74.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"81.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"58.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"94.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"131.5","Single Cell Type RNA - Club cells [nTPM]":"163.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"150.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"64.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"248.0","Single Cell Type RNA - dendritic cells [nTPM]":"65.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"95.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"776.7","Single Cell Type RNA - Ductal cells [nTPM]":"218.4","Single Cell Type RNA - Early spermatids [nTPM]":"18.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"87.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"63.8","Single Cell Type RNA - Endothelial cells [nTPM]":"80.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"66.8","Single Cell Type RNA - Erythroid cells [nTPM]":"81.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"145.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"248.5","Single Cell Type RNA - Fibroblasts [nTPM]":"79.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"79.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"62.6","Single Cell Type RNA - granulocytes [nTPM]":"58.3","Single Cell Type RNA - Granulosa cells [nTPM]":"66.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"83.2","Single Cell Type RNA - Hepatocytes [nTPM]":"249.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"237.3","Single Cell Type RNA - Horizontal cells [nTPM]":"72.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"27.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"103.4","Single Cell Type RNA - Ionocytes [nTPM]":"215.7","Single Cell Type RNA - Kupffer cells [nTPM]":"100.6","Single Cell Type RNA - Langerhans cells [nTPM]":"74.4","Single Cell Type RNA - Late spermatids [nTPM]":"34.7","Single Cell Type RNA - Leydig cells [nTPM]":"102.9","Single Cell Type RNA - Macrophages [nTPM]":"94.6","Single Cell Type RNA - Melanocytes [nTPM]":"129.9","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"176.1","Single Cell Type RNA - Muller glia cells [nTPM]":"107.8","Single Cell Type RNA - NK-cells [nTPM]":"107.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"24.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"142.7","Single Cell Type RNA - Paneth cells [nTPM]":"89.5","Single Cell Type RNA - Peritubular cells [nTPM]":"109.1","Single Cell Type RNA - Plasma cells [nTPM]":"71.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"100.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"139.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"916.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"177.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"69.3","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"74.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"94.4","Single Cell Type RNA - Spermatocytes [nTPM]":"115.3","Single Cell Type RNA - Spermatogonia [nTPM]":"114.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"111.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"76.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"307.6","Single Cell Type RNA - T-cells [nTPM]":"72.0","Single Cell Type RNA - Theca cells [nTPM]":"215.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"154.2","Single Cell Type RNA - Urothelial cells [nTPM]":"155.0"},{"Gene":"SEC31A","Gene synonym":["ABP125","ABP130","KIAA0905","SEC31L1"],"Ensembl":"ENSG00000138674","Gene description":"SEC31 homolog A, COPII coat complex component","Uniprot":["O94979"],"Chromosome":"4","Position":"82818509-82901166","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["ER-Golgi transport","Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005457"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"40000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA005457":"AB_1079896"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.32e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.69e-4"},"Tissue RNA - adipose tissue [nTPM]":"98.7","Tissue RNA - adrenal gland [nTPM]":"103.3","Tissue RNA - amygdala [nTPM]":"52.2","Tissue RNA - appendix [nTPM]":"78.4","Tissue RNA - basal ganglia [nTPM]":"54.3","Tissue RNA - bone marrow [nTPM]":"119.4","Tissue RNA - breast [nTPM]":"111.4","Tissue RNA - cerebellum [nTPM]":"62.4","Tissue RNA - cerebral cortex [nTPM]":"70.1","Tissue RNA - cervix [nTPM]":"145.5","Tissue RNA - choroid plexus [nTPM]":"94.9","Tissue RNA - colon [nTPM]":"107.1","Tissue RNA - duodenum [nTPM]":"124.2","Tissue RNA - endometrium 1 [nTPM]":"119.7","Tissue RNA - epididymis [nTPM]":"162.1","Tissue RNA - esophagus [nTPM]":"92.6","Tissue RNA - fallopian tube [nTPM]":"90.9","Tissue RNA - gallbladder [nTPM]":"122.1","Tissue RNA - heart muscle [nTPM]":"110.7","Tissue RNA - hippocampal formation [nTPM]":"54.0","Tissue RNA - hypothalamus [nTPM]":"61.4","Tissue RNA - kidney [nTPM]":"133.6","Tissue RNA - liver [nTPM]":"174.8","Tissue RNA - lung [nTPM]":"96.2","Tissue RNA - lymph node [nTPM]":"88.2","Tissue RNA - medulla oblongata [nTPM]":"58.4","Tissue RNA - midbrain [nTPM]":"58.7","Tissue RNA - ovary [nTPM]":"152.8","Tissue RNA - pancreas [nTPM]":"192.6","Tissue RNA - parathyroid gland [nTPM]":"116.4","Tissue RNA - pituitary gland [nTPM]":"108.4","Tissue RNA - placenta [nTPM]":"143.2","Tissue RNA - pons [nTPM]":"58.7","Tissue RNA - prostate [nTPM]":"113.4","Tissue RNA - rectum [nTPM]":"127.2","Tissue RNA - retina [nTPM]":"87.9","Tissue RNA - salivary gland [nTPM]":"134.0","Tissue RNA - seminal vesicle [nTPM]":"111.3","Tissue RNA - skeletal muscle [nTPM]":"96.8","Tissue RNA - skin 1 [nTPM]":"107.8","Tissue RNA - small intestine [nTPM]":"111.0","Tissue RNA - smooth muscle [nTPM]":"131.5","Tissue RNA - spinal cord [nTPM]":"50.9","Tissue RNA - spleen [nTPM]":"76.5","Tissue RNA - stomach 1 [nTPM]":"110.1","Tissue RNA - testis [nTPM]":"77.8","Tissue RNA - thalamus [nTPM]":"54.4","Tissue RNA - thymus [nTPM]":"93.8","Tissue RNA - thyroid gland [nTPM]":"168.0","Tissue RNA - tongue [nTPM]":"85.6","Tissue RNA - tonsil [nTPM]":"102.1","Tissue RNA - urinary bladder [nTPM]":"113.1","Tissue RNA - vagina [nTPM]":"94.1","Tissue RNA - white matter [nTPM]":"63.9","Cell RNA - A-431 [nTPM]":"146.2","Cell RNA - A549 [nTPM]":"65.2","Cell RNA - AF22 [nTPM]":"183.6","Cell RNA - AN3-CA [nTPM]":"130.4","Cell RNA - ASC diff [nTPM]":"318.9","Cell RNA - ASC TERT1 [nTPM]":"394.5","Cell RNA - BEWO [nTPM]":"133.3","Cell RNA - BJ [nTPM]":"264.8","Cell RNA - BJ hTERT+ [nTPM]":"295.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"146.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"179.2","Cell RNA - CACO-2 [nTPM]":"113.2","Cell RNA - CAPAN-2 [nTPM]":"182.3","Cell RNA - Daudi [nTPM]":"188.3","Cell RNA - EFO-21 [nTPM]":"113.7","Cell RNA - fHDF\/TERT166 [nTPM]":"532.2","Cell RNA - GAMG [nTPM]":"84.6","Cell RNA - HaCaT [nTPM]":"68.1","Cell RNA - HAP1 [nTPM]":"183.3","Cell RNA - HBEC3-KT [nTPM]":"176.2","Cell RNA - HBF TERT88 [nTPM]":"200.4","Cell RNA - HDLM-2 [nTPM]":"193.4","Cell RNA - HEK 293 [nTPM]":"72.7","Cell RNA - HEL [nTPM]":"115.3","Cell RNA - HeLa [nTPM]":"110.5","Cell RNA - Hep G2 [nTPM]":"302.1","Cell RNA - HHSteC [nTPM]":"316.4","Cell RNA - HL-60 [nTPM]":"124.4","Cell RNA - HMC-1 [nTPM]":"140.7","Cell RNA - HSkMC [nTPM]":"380.5","Cell RNA - hTCEpi [nTPM]":"217.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"223.5","Cell RNA - hTERT-HME1 [nTPM]":"254.3","Cell RNA - hTERT-RPE1 [nTPM]":"251.2","Cell RNA - HUVEC TERT2 [nTPM]":"240.5","Cell RNA - JURKAT [nTPM]":"83.8","Cell RNA - K-562 [nTPM]":"178.4","Cell RNA - Karpas-707 [nTPM]":"181.1","Cell RNA - LHCN-M2 [nTPM]":"264.2","Cell RNA - MCF7 [nTPM]":"128.6","Cell RNA - MOLT-4 [nTPM]":"164.9","Cell RNA - NB-4 [nTPM]":"99.6","Cell RNA - NTERA-2 [nTPM]":"126.1","Cell RNA - OE19 [nTPM]":"154.0","Cell RNA - PC-3 [nTPM]":"58.3","Cell RNA - REH [nTPM]":"121.2","Cell RNA - RH-30 [nTPM]":"100.1","Cell RNA - RPMI-8226 [nTPM]":"140.3","Cell RNA - RPTEC TERT1 [nTPM]":"237.2","Cell RNA - RT4 [nTPM]":"83.0","Cell RNA - SCLC-21H [nTPM]":"118.6","Cell RNA - SH-SY5Y [nTPM]":"131.2","Cell RNA - SiHa [nTPM]":"105.7","Cell RNA - SK-BR-3 [nTPM]":"180.7","Cell RNA - SK-MEL-30 [nTPM]":"174.9","Cell RNA - SuSa [nTPM]":"184.8","Cell RNA - T-47d [nTPM]":"142.1","Cell RNA - THP-1 [nTPM]":"137.8","Cell RNA - TIME [nTPM]":"248.2","Cell RNA - U-138 MG [nTPM]":"190.7","Cell RNA - U-2 OS [nTPM]":"98.9","Cell RNA - U-2197 [nTPM]":"169.0","Cell RNA - U-251 MG [nTPM]":"168.8","Cell RNA - U-266\/70 [nTPM]":"135.1","Cell RNA - U-266\/84 [nTPM]":"62.4","Cell RNA - U-698 [nTPM]":"256.7","Cell RNA - U-87 MG [nTPM]":"190.6","Cell RNA - U-937 [nTPM]":"147.8","Cell RNA - WM-115 [nTPM]":"224.2","Blood RNA - basophil [nTPM]":"84.3","Blood RNA - classical monocyte [nTPM]":"66.9","Blood RNA - eosinophil [nTPM]":"51.2","Blood RNA - gdT-cell [nTPM]":"65.1","Blood RNA - intermediate monocyte [nTPM]":"74.0","Blood RNA - MAIT T-cell [nTPM]":"80.5","Blood RNA - memory B-cell [nTPM]":"60.0","Blood RNA - memory CD4 T-cell [nTPM]":"57.6","Blood RNA - memory CD8 T-cell [nTPM]":"64.3","Blood RNA - myeloid DC [nTPM]":"73.3","Blood RNA - naive B-cell [nTPM]":"50.0","Blood RNA - naive CD4 T-cell [nTPM]":"56.9","Blood RNA - naive CD8 T-cell [nTPM]":"54.6","Blood RNA - neutrophil [nTPM]":"19.2","Blood RNA - NK-cell [nTPM]":"89.9","Blood RNA - non-classical monocyte [nTPM]":"83.1","Blood RNA - plasmacytoid DC [nTPM]":"61.1","Blood RNA - T-reg [nTPM]":"52.7","Blood RNA - total PBMC [nTPM]":"71.8","Brain RNA - amygdala [nTPM]":"52.2","Brain RNA - basal ganglia [nTPM]":"54.3","Brain RNA - cerebellum [nTPM]":"62.4","Brain RNA - cerebral cortex [nTPM]":"70.1","Brain RNA - hippocampal formation [nTPM]":"54.0","Brain RNA - hypothalamus [nTPM]":"61.4","Brain RNA - medulla oblongata [nTPM]":"58.4","Brain RNA - midbrain [nTPM]":"58.7","Brain RNA - pons [nTPM]":"58.7","Brain RNA - spinal cord [nTPM]":"50.9","Brain RNA - thalamus [nTPM]":"54.4","Brain RNA - white matter [nTPM]":"63.9","Single Cell Type RNA - Adipocytes [nTPM]":"62.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"105.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"85.3","Single Cell Type RNA - Astrocytes [nTPM]":"50.9","Single Cell Type RNA - B-cells [nTPM]":"58.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"60.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"60.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"64.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"56.9","Single Cell Type RNA - Bipolar cells [nTPM]":"52.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"54.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"43.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"85.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"51.5","Single Cell Type RNA - Club cells [nTPM]":"109.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"47.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"54.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"57.3","Single Cell Type RNA - dendritic cells [nTPM]":"61.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"62.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"27.4","Single Cell Type RNA - Ductal cells [nTPM]":"65.8","Single Cell Type RNA - Early spermatids [nTPM]":"30.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"90.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"164.6","Single Cell Type RNA - Endothelial cells [nTPM]":"65.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"38.3","Single Cell Type RNA - Erythroid cells [nTPM]":"41.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"61.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"71.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"85.3","Single Cell Type RNA - Fibroblasts [nTPM]":"125.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"100.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"119.7","Single Cell Type RNA - granulocytes [nTPM]":"75.2","Single Cell Type RNA - Granulosa cells [nTPM]":"241.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"65.0","Single Cell Type RNA - Hepatocytes [nTPM]":"94.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"45.9","Single Cell Type RNA - Horizontal cells [nTPM]":"42.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"60.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"99.4","Single Cell Type RNA - Ionocytes [nTPM]":"50.8","Single Cell Type RNA - Kupffer cells [nTPM]":"51.2","Single Cell Type RNA - Langerhans cells [nTPM]":"55.3","Single Cell Type RNA - Late spermatids [nTPM]":"19.3","Single Cell Type RNA - Leydig cells [nTPM]":"139.1","Single Cell Type RNA - Macrophages [nTPM]":"63.8","Single Cell Type RNA - Melanocytes [nTPM]":"51.6","Single Cell Type RNA - Microglial cells [nTPM]":"67.5","Single Cell Type RNA - monocytes [nTPM]":"60.4","Single Cell Type RNA - Muller glia cells [nTPM]":"36.5","Single Cell Type RNA - NK-cells [nTPM]":"38.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"74.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"72.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"67.5","Single Cell Type RNA - Paneth cells [nTPM]":"46.3","Single Cell Type RNA - Peritubular cells [nTPM]":"126.0","Single Cell Type RNA - Plasma cells [nTPM]":"152.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"76.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"121.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"65.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"100.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"66.9","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"86.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"98.9","Single Cell Type RNA - Spermatocytes [nTPM]":"30.3","Single Cell Type RNA - Spermatogonia [nTPM]":"34.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"62.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"74.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"81.5","Single Cell Type RNA - T-cells [nTPM]":"55.4","Single Cell Type RNA - Theca cells [nTPM]":"78.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"54.9","Single Cell Type RNA - Urothelial cells [nTPM]":"101.1"},{"Gene":"SEC61A1","Gene synonym":[],"Ensembl":"ENSG00000058262","Gene description":"SEC61 translocon subunit alpha 1","Uniprot":["P61619"],"Chromosome":"3","Position":"128051641-128071683","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Translocation","Transport"],"Molecular function":["Chaperone"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022076"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB022076":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.82e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.07e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.84e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Tissue RNA - adipose tissue [nTPM]":"82.1","Tissue RNA - adrenal gland [nTPM]":"100.7","Tissue RNA - amygdala [nTPM]":"31.3","Tissue RNA - appendix [nTPM]":"88.3","Tissue RNA - basal ganglia [nTPM]":"33.4","Tissue RNA - bone marrow [nTPM]":"79.5","Tissue RNA - breast [nTPM]":"75.3","Tissue RNA - cerebellum [nTPM]":"33.5","Tissue RNA - cerebral cortex [nTPM]":"34.7","Tissue RNA - cervix [nTPM]":"144.5","Tissue RNA - choroid plexus [nTPM]":"52.4","Tissue RNA - colon [nTPM]":"90.7","Tissue RNA - duodenum [nTPM]":"81.9","Tissue RNA - endometrium 1 [nTPM]":"88.9","Tissue RNA - epididymis [nTPM]":"128.9","Tissue RNA - esophagus [nTPM]":"88.7","Tissue RNA - fallopian tube [nTPM]":"78.1","Tissue RNA - gallbladder [nTPM]":"81.7","Tissue RNA - heart muscle [nTPM]":"74.2","Tissue RNA - hippocampal formation [nTPM]":"32.3","Tissue RNA - hypothalamus [nTPM]":"39.6","Tissue RNA - kidney [nTPM]":"64.6","Tissue RNA - liver [nTPM]":"134.8","Tissue RNA - lung [nTPM]":"93.3","Tissue RNA - lymph node [nTPM]":"60.2","Tissue RNA - medulla oblongata [nTPM]":"40.9","Tissue RNA - midbrain [nTPM]":"37.6","Tissue RNA - ovary [nTPM]":"67.3","Tissue RNA - pancreas [nTPM]":"272.1","Tissue RNA - parathyroid gland [nTPM]":"111.7","Tissue RNA - pituitary gland [nTPM]":"93.5","Tissue RNA - placenta [nTPM]":"112.8","Tissue RNA - pons [nTPM]":"36.0","Tissue RNA - prostate [nTPM]":"90.0","Tissue RNA - rectum [nTPM]":"90.0","Tissue RNA - retina [nTPM]":"37.0","Tissue RNA - salivary gland [nTPM]":"176.3","Tissue RNA - seminal vesicle [nTPM]":"97.0","Tissue RNA - skeletal muscle [nTPM]":"70.5","Tissue RNA - skin 1 [nTPM]":"66.9","Tissue RNA - small intestine [nTPM]":"75.8","Tissue RNA - smooth muscle [nTPM]":"110.7","Tissue RNA - spinal cord [nTPM]":"36.6","Tissue RNA - spleen [nTPM]":"73.7","Tissue RNA - stomach 1 [nTPM]":"105.5","Tissue RNA - testis [nTPM]":"38.8","Tissue RNA - thalamus [nTPM]":"46.6","Tissue RNA - thymus [nTPM]":"61.4","Tissue RNA - thyroid gland [nTPM]":"104.8","Tissue RNA - tongue [nTPM]":"59.3","Tissue RNA - tonsil [nTPM]":"80.6","Tissue RNA - urinary bladder [nTPM]":"97.0","Tissue RNA - vagina [nTPM]":"68.7","Tissue RNA - white matter [nTPM]":"35.8","Cell RNA - A-431 [nTPM]":"272.8","Cell RNA - A549 [nTPM]":"136.5","Cell RNA - AF22 [nTPM]":"132.0","Cell RNA - AN3-CA [nTPM]":"240.3","Cell RNA - ASC diff [nTPM]":"367.9","Cell RNA - ASC TERT1 [nTPM]":"317.3","Cell RNA - BEWO [nTPM]":"256.9","Cell RNA - BJ [nTPM]":"426.9","Cell RNA - BJ hTERT+ [nTPM]":"470.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"349.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"371.2","Cell RNA - CACO-2 [nTPM]":"259.1","Cell RNA - CAPAN-2 [nTPM]":"186.9","Cell RNA - Daudi [nTPM]":"184.7","Cell RNA - EFO-21 [nTPM]":"259.5","Cell RNA - fHDF\/TERT166 [nTPM]":"534.8","Cell RNA - GAMG [nTPM]":"266.2","Cell RNA - HaCaT [nTPM]":"232.6","Cell RNA - HAP1 [nTPM]":"209.0","Cell RNA - HBEC3-KT [nTPM]":"291.3","Cell RNA - HBF TERT88 [nTPM]":"334.2","Cell RNA - HDLM-2 [nTPM]":"168.1","Cell RNA - HEK 293 [nTPM]":"126.2","Cell RNA - HEL [nTPM]":"213.5","Cell RNA - HeLa [nTPM]":"143.5","Cell RNA - Hep G2 [nTPM]":"273.6","Cell RNA - HHSteC [nTPM]":"542.9","Cell RNA - HL-60 [nTPM]":"264.1","Cell RNA - HMC-1 [nTPM]":"225.9","Cell RNA - HSkMC [nTPM]":"348.1","Cell RNA - hTCEpi [nTPM]":"345.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"329.3","Cell RNA - hTERT-HME1 [nTPM]":"422.4","Cell RNA - hTERT-RPE1 [nTPM]":"265.0","Cell RNA - HUVEC TERT2 [nTPM]":"314.3","Cell RNA - JURKAT [nTPM]":"122.2","Cell RNA - K-562 [nTPM]":"136.9","Cell RNA - Karpas-707 [nTPM]":"415.3","Cell RNA - LHCN-M2 [nTPM]":"412.8","Cell RNA - MCF7 [nTPM]":"237.7","Cell RNA - MOLT-4 [nTPM]":"135.1","Cell RNA - NB-4 [nTPM]":"87.5","Cell RNA - NTERA-2 [nTPM]":"184.6","Cell RNA - OE19 [nTPM]":"231.6","Cell RNA - PC-3 [nTPM]":"202.8","Cell RNA - REH [nTPM]":"144.2","Cell RNA - RH-30 [nTPM]":"125.5","Cell RNA - RPMI-8226 [nTPM]":"349.8","Cell RNA - RPTEC TERT1 [nTPM]":"181.4","Cell RNA - RT4 [nTPM]":"229.3","Cell RNA - SCLC-21H [nTPM]":"155.8","Cell RNA - SH-SY5Y [nTPM]":"162.4","Cell RNA - SiHa [nTPM]":"216.0","Cell RNA - SK-BR-3 [nTPM]":"193.5","Cell RNA - SK-MEL-30 [nTPM]":"270.7","Cell RNA - SuSa [nTPM]":"152.0","Cell RNA - T-47d [nTPM]":"184.2","Cell RNA - THP-1 [nTPM]":"215.1","Cell RNA - TIME [nTPM]":"327.3","Cell RNA - U-138 MG [nTPM]":"278.3","Cell RNA - U-2 OS [nTPM]":"164.7","Cell RNA - U-2197 [nTPM]":"333.7","Cell RNA - U-251 MG [nTPM]":"201.4","Cell RNA - U-266\/70 [nTPM]":"386.6","Cell RNA - U-266\/84 [nTPM]":"210.6","Cell RNA - U-698 [nTPM]":"265.8","Cell RNA - U-87 MG [nTPM]":"456.3","Cell RNA - U-937 [nTPM]":"166.2","Cell RNA - WM-115 [nTPM]":"369.1","Blood RNA - basophil [nTPM]":"160.3","Blood RNA - classical monocyte [nTPM]":"88.6","Blood RNA - eosinophil [nTPM]":"67.0","Blood RNA - gdT-cell [nTPM]":"89.0","Blood RNA - intermediate monocyte [nTPM]":"79.6","Blood RNA - MAIT T-cell [nTPM]":"120.0","Blood RNA - memory B-cell [nTPM]":"43.8","Blood RNA - memory CD4 T-cell [nTPM]":"62.9","Blood RNA - memory CD8 T-cell [nTPM]":"78.2","Blood RNA - myeloid DC [nTPM]":"82.6","Blood RNA - naive B-cell [nTPM]":"26.1","Blood RNA - naive CD4 T-cell [nTPM]":"38.8","Blood RNA - naive CD8 T-cell [nTPM]":"46.2","Blood RNA - neutrophil [nTPM]":"22.5","Blood RNA - NK-cell [nTPM]":"65.0","Blood RNA - non-classical monocyte [nTPM]":"84.2","Blood RNA - plasmacytoid DC [nTPM]":"114.0","Blood RNA - T-reg [nTPM]":"45.1","Blood RNA - total PBMC [nTPM]":"116.9","Brain RNA - amygdala [nTPM]":"31.3","Brain RNA - basal ganglia [nTPM]":"33.4","Brain RNA - cerebellum [nTPM]":"33.5","Brain RNA - cerebral cortex [nTPM]":"34.7","Brain RNA - hippocampal formation [nTPM]":"32.3","Brain RNA - hypothalamus [nTPM]":"39.6","Brain RNA - medulla oblongata [nTPM]":"40.9","Brain RNA - midbrain [nTPM]":"37.6","Brain RNA - pons [nTPM]":"36.0","Brain RNA - spinal cord [nTPM]":"36.6","Brain RNA - thalamus [nTPM]":"46.6","Brain RNA - white matter [nTPM]":"35.8","Single Cell Type RNA - Adipocytes [nTPM]":"31.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"33.1","Single Cell Type RNA - Astrocytes [nTPM]":"18.6","Single Cell Type RNA - B-cells [nTPM]":"46.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"37.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"25.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"44.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"30.7","Single Cell Type RNA - Bipolar cells [nTPM]":"17.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"63.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"41.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"37.1","Single Cell Type RNA - Club cells [nTPM]":"43.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"49.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"64.3","Single Cell Type RNA - dendritic cells [nTPM]":"59.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"107.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"81.0","Single Cell Type RNA - Early spermatids [nTPM]":"42.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"28.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"72.9","Single Cell Type RNA - Endothelial cells [nTPM]":"45.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"73.6","Single Cell Type RNA - Erythroid cells [nTPM]":"19.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"154.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"136.3","Single Cell Type RNA - Fibroblasts [nTPM]":"57.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"77.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"68.6","Single Cell Type RNA - granulocytes [nTPM]":"26.0","Single Cell Type RNA - Granulosa cells [nTPM]":"55.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"49.6","Single Cell Type RNA - Hepatocytes [nTPM]":"118.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"75.9","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"150.8","Single Cell Type RNA - Ionocytes [nTPM]":"38.7","Single Cell Type RNA - Kupffer cells [nTPM]":"34.8","Single Cell Type RNA - Langerhans cells [nTPM]":"32.1","Single Cell Type RNA - Late spermatids [nTPM]":"25.7","Single Cell Type RNA - Leydig cells [nTPM]":"41.0","Single Cell Type RNA - Macrophages [nTPM]":"38.2","Single Cell Type RNA - Melanocytes [nTPM]":"33.8","Single Cell Type RNA - Microglial cells [nTPM]":"26.2","Single Cell Type RNA - monocytes [nTPM]":"32.1","Single Cell Type RNA - Muller glia cells [nTPM]":"22.4","Single Cell Type RNA - NK-cells [nTPM]":"28.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"104.9","Single Cell Type RNA - Paneth cells [nTPM]":"50.2","Single Cell Type RNA - Peritubular cells [nTPM]":"43.6","Single Cell Type RNA - Plasma cells [nTPM]":"192.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"69.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"63.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"26.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"31.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.5","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"25.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"47.2","Single Cell Type RNA - Spermatocytes [nTPM]":"12.3","Single Cell Type RNA - Spermatogonia [nTPM]":"18.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"42.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"29.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"127.9","Single Cell Type RNA - T-cells [nTPM]":"32.4","Single Cell Type RNA - Theca cells [nTPM]":"52.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"100.4","Single Cell Type RNA - Urothelial cells [nTPM]":"44.6"},{"Gene":"SEC63","Gene synonym":["DNAJC23","ERdj2","PRO2507","SEC63L"],"Ensembl":"ENSG00000025796","Gene description":"SEC63 homolog, protein translocation regulator","Uniprot":["Q9UGP8"],"Chromosome":"6","Position":"107867756-107958208","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":["Chaperone"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Theca cells":"354.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053295","HPA060535"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA053295":"AB_2682105","HPA060535":"AB_2684312"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.32e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.01e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.16e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Tissue RNA - adipose tissue [nTPM]":"27.5","Tissue RNA - adrenal gland [nTPM]":"33.0","Tissue RNA - amygdala [nTPM]":"11.6","Tissue RNA - appendix [nTPM]":"22.0","Tissue RNA - basal ganglia [nTPM]":"14.3","Tissue RNA - bone marrow [nTPM]":"32.9","Tissue RNA - breast [nTPM]":"23.3","Tissue RNA - cerebellum [nTPM]":"14.4","Tissue RNA - cerebral cortex [nTPM]":"12.9","Tissue RNA - cervix [nTPM]":"30.2","Tissue RNA - choroid plexus [nTPM]":"25.7","Tissue RNA - colon [nTPM]":"19.2","Tissue RNA - duodenum [nTPM]":"16.8","Tissue RNA - endometrium 1 [nTPM]":"25.2","Tissue RNA - epididymis [nTPM]":"29.6","Tissue RNA - esophagus [nTPM]":"19.5","Tissue RNA - fallopian tube [nTPM]":"21.8","Tissue RNA - gallbladder [nTPM]":"22.0","Tissue RNA - heart muscle [nTPM]":"19.0","Tissue RNA - hippocampal formation [nTPM]":"12.4","Tissue RNA - hypothalamus [nTPM]":"15.3","Tissue RNA - kidney [nTPM]":"20.0","Tissue RNA - liver [nTPM]":"46.6","Tissue RNA - lung [nTPM]":"21.7","Tissue RNA - lymph node [nTPM]":"16.7","Tissue RNA - medulla oblongata [nTPM]":"13.3","Tissue RNA - midbrain [nTPM]":"12.0","Tissue RNA - ovary [nTPM]":"40.4","Tissue RNA - pancreas [nTPM]":"61.2","Tissue RNA - parathyroid gland [nTPM]":"31.7","Tissue RNA - pituitary gland [nTPM]":"14.4","Tissue RNA - placenta [nTPM]":"20.9","Tissue RNA - pons [nTPM]":"14.2","Tissue RNA - prostate [nTPM]":"27.7","Tissue RNA - rectum [nTPM]":"18.6","Tissue RNA - retina [nTPM]":"21.2","Tissue RNA - salivary gland [nTPM]":"77.8","Tissue RNA - seminal vesicle [nTPM]":"23.3","Tissue RNA - skeletal muscle [nTPM]":"14.3","Tissue RNA - skin 1 [nTPM]":"15.5","Tissue RNA - small intestine [nTPM]":"18.0","Tissue RNA - smooth muscle [nTPM]":"22.2","Tissue RNA - spinal cord [nTPM]":"12.3","Tissue RNA - spleen [nTPM]":"16.1","Tissue RNA - stomach 1 [nTPM]":"23.1","Tissue RNA - testis [nTPM]":"33.0","Tissue RNA - thalamus [nTPM]":"12.1","Tissue RNA - thymus [nTPM]":"22.6","Tissue RNA - thyroid gland [nTPM]":"52.1","Tissue RNA - tongue [nTPM]":"14.1","Tissue RNA - tonsil [nTPM]":"17.3","Tissue RNA - urinary bladder [nTPM]":"21.8","Tissue RNA - vagina [nTPM]":"14.0","Tissue RNA - white matter [nTPM]":"17.7","Cell RNA - A-431 [nTPM]":"28.5","Cell RNA - A549 [nTPM]":"17.1","Cell RNA - AF22 [nTPM]":"46.0","Cell RNA - AN3-CA [nTPM]":"57.6","Cell RNA - ASC diff [nTPM]":"47.1","Cell RNA - ASC TERT1 [nTPM]":"55.2","Cell RNA - BEWO [nTPM]":"41.4","Cell RNA - BJ [nTPM]":"59.2","Cell RNA - BJ hTERT+ [nTPM]":"65.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"27.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"39.2","Cell RNA - CACO-2 [nTPM]":"30.8","Cell RNA - CAPAN-2 [nTPM]":"34.6","Cell RNA - Daudi [nTPM]":"52.8","Cell RNA - EFO-21 [nTPM]":"49.4","Cell RNA - fHDF\/TERT166 [nTPM]":"53.7","Cell RNA - GAMG [nTPM]":"34.4","Cell RNA - HaCaT [nTPM]":"40.9","Cell RNA - HAP1 [nTPM]":"32.3","Cell RNA - HBEC3-KT [nTPM]":"38.3","Cell RNA - HBF TERT88 [nTPM]":"42.5","Cell RNA - HDLM-2 [nTPM]":"63.8","Cell RNA - HEK 293 [nTPM]":"35.7","Cell RNA - HEL [nTPM]":"57.2","Cell RNA - HeLa [nTPM]":"25.2","Cell RNA - Hep G2 [nTPM]":"31.6","Cell RNA - HHSteC [nTPM]":"73.2","Cell RNA - HL-60 [nTPM]":"65.9","Cell RNA - HMC-1 [nTPM]":"32.5","Cell RNA - HSkMC [nTPM]":"43.5","Cell RNA - hTCEpi [nTPM]":"61.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"44.5","Cell RNA - hTERT-HME1 [nTPM]":"97.6","Cell RNA - hTERT-RPE1 [nTPM]":"50.0","Cell RNA - HUVEC TERT2 [nTPM]":"39.3","Cell RNA - JURKAT [nTPM]":"31.7","Cell RNA - K-562 [nTPM]":"48.5","Cell RNA - Karpas-707 [nTPM]":"82.8","Cell RNA - LHCN-M2 [nTPM]":"57.7","Cell RNA - MCF7 [nTPM]":"22.7","Cell RNA - MOLT-4 [nTPM]":"20.6","Cell RNA - NB-4 [nTPM]":"29.5","Cell RNA - NTERA-2 [nTPM]":"36.4","Cell RNA - OE19 [nTPM]":"30.0","Cell RNA - PC-3 [nTPM]":"18.1","Cell RNA - REH [nTPM]":"65.2","Cell RNA - RH-30 [nTPM]":"54.4","Cell RNA - RPMI-8226 [nTPM]":"43.7","Cell RNA - RPTEC TERT1 [nTPM]":"33.5","Cell RNA - RT4 [nTPM]":"37.1","Cell RNA - SCLC-21H [nTPM]":"40.3","Cell RNA - SH-SY5Y [nTPM]":"45.7","Cell RNA - SiHa [nTPM]":"32.9","Cell RNA - SK-BR-3 [nTPM]":"48.8","Cell RNA - SK-MEL-30 [nTPM]":"59.1","Cell RNA - SuSa [nTPM]":"31.2","Cell RNA - T-47d [nTPM]":"34.9","Cell RNA - THP-1 [nTPM]":"95.8","Cell RNA - TIME [nTPM]":"42.5","Cell RNA - U-138 MG [nTPM]":"41.6","Cell RNA - U-2 OS [nTPM]":"25.8","Cell RNA - U-2197 [nTPM]":"42.2","Cell RNA - U-251 MG [nTPM]":"46.6","Cell RNA - U-266\/70 [nTPM]":"31.4","Cell RNA - U-266\/84 [nTPM]":"25.0","Cell RNA - U-698 [nTPM]":"52.9","Cell RNA - U-87 MG [nTPM]":"45.9","Cell RNA - U-937 [nTPM]":"56.4","Cell RNA - WM-115 [nTPM]":"48.7","Blood RNA - basophil [nTPM]":"5.6","Blood RNA - classical monocyte [nTPM]":"5.2","Blood RNA - eosinophil [nTPM]":"5.0","Blood RNA - gdT-cell [nTPM]":"4.8","Blood RNA - intermediate monocyte [nTPM]":"4.7","Blood RNA - MAIT T-cell [nTPM]":"7.5","Blood RNA - memory B-cell [nTPM]":"4.4","Blood RNA - memory CD4 T-cell [nTPM]":"3.9","Blood RNA - memory CD8 T-cell [nTPM]":"3.9","Blood RNA - myeloid DC [nTPM]":"5.4","Blood RNA - naive B-cell [nTPM]":"4.0","Blood RNA - naive CD4 T-cell [nTPM]":"4.3","Blood RNA - naive CD8 T-cell [nTPM]":"3.4","Blood RNA - neutrophil [nTPM]":"1.7","Blood RNA - NK-cell [nTPM]":"7.1","Blood RNA - non-classical monocyte [nTPM]":"9.8","Blood RNA - plasmacytoid DC [nTPM]":"6.9","Blood RNA - T-reg [nTPM]":"2.2","Blood RNA - total PBMC [nTPM]":"3.5","Brain RNA - amygdala [nTPM]":"11.6","Brain RNA - basal ganglia [nTPM]":"14.3","Brain RNA - cerebellum [nTPM]":"14.4","Brain RNA - cerebral cortex [nTPM]":"12.9","Brain RNA - hippocampal formation [nTPM]":"12.4","Brain RNA - hypothalamus [nTPM]":"15.3","Brain RNA - medulla oblongata [nTPM]":"13.3","Brain RNA - midbrain [nTPM]":"12.0","Brain RNA - pons [nTPM]":"14.2","Brain RNA - spinal cord [nTPM]":"12.3","Brain RNA - thalamus [nTPM]":"12.1","Brain RNA - white matter [nTPM]":"17.7","Single Cell Type RNA - Adipocytes [nTPM]":"55.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"118.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"143.3","Single Cell Type RNA - Astrocytes [nTPM]":"38.2","Single Cell Type RNA - B-cells [nTPM]":"64.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"85.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"70.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"90.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"42.7","Single Cell Type RNA - Bipolar cells [nTPM]":"57.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"67.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"54.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"78.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"81.5","Single Cell Type RNA - Club cells [nTPM]":"125.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"53.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"80.8","Single Cell Type RNA - dendritic cells [nTPM]":"71.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"39.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"86.0","Single Cell Type RNA - Early spermatids [nTPM]":"40.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"48.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"102.8","Single Cell Type RNA - Endothelial cells [nTPM]":"61.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"53.5","Single Cell Type RNA - Erythroid cells [nTPM]":"31.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"52.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"125.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"96.4","Single Cell Type RNA - Fibroblasts [nTPM]":"107.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"46.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"54.8","Single Cell Type RNA - granulocytes [nTPM]":"68.9","Single Cell Type RNA - Granulosa cells [nTPM]":"84.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"59.6","Single Cell Type RNA - Hepatocytes [nTPM]":"126.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"62.7","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"50.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"80.0","Single Cell Type RNA - Ionocytes [nTPM]":"83.4","Single Cell Type RNA - Kupffer cells [nTPM]":"56.7","Single Cell Type RNA - Langerhans cells [nTPM]":"78.9","Single Cell Type RNA - Late spermatids [nTPM]":"23.9","Single Cell Type RNA - Leydig cells [nTPM]":"106.2","Single Cell Type RNA - Macrophages [nTPM]":"54.8","Single Cell Type RNA - Melanocytes [nTPM]":"80.0","Single Cell Type RNA - Microglial cells [nTPM]":"42.2","Single Cell Type RNA - monocytes [nTPM]":"54.3","Single Cell Type RNA - Muller glia cells [nTPM]":"61.0","Single Cell Type RNA - NK-cells [nTPM]":"59.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"60.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"64.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"81.9","Single Cell Type RNA - Paneth cells [nTPM]":"53.5","Single Cell Type RNA - Peritubular cells [nTPM]":"118.8","Single Cell Type RNA - Plasma cells [nTPM]":"144.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"91.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"37.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"38.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"116.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"49.9","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"108.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"77.2","Single Cell Type RNA - Spermatocytes [nTPM]":"143.1","Single Cell Type RNA - Spermatogonia [nTPM]":"75.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"44.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"80.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"91.0","Single Cell Type RNA - T-cells [nTPM]":"52.3","Single Cell Type RNA - Theca cells [nTPM]":"354.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"60.8","Single Cell Type RNA - Urothelial cells [nTPM]":"73.8"},{"Gene":"SELENBP1","Gene synonym":["hSBP","hSP56","LPSB"],"Ensembl":"ENSG00000143416","Gene description":"Selenium binding protein 1","Uniprot":["Q13228"],"Chromosome":"1","Position":"151364304-151372707","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"509.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"525.6","Distal enterocytes":"1056.9","Erythroid cells":"590.9","Hepatocytes":"501.5","Paneth cells":"451.4","Undifferentiated cells":"452.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"2.4"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"dendritic cells":"2.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"144.9","HEL":"120.5","HSkMC":"75.9","OE19":"92.8","SK-BR-3":"274.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005741","CAB008366","HPA011731"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"59000000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"CAB008366":"AB_592677","HPA005741":"AB_1856662","HPA011731":"AB_1856663"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.52e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.25e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.63e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-3"},"Tissue RNA - adipose tissue [nTPM]":"128.3","Tissue RNA - adrenal gland [nTPM]":"18.7","Tissue RNA - amygdala [nTPM]":"49.8","Tissue RNA - appendix [nTPM]":"24.9","Tissue RNA - basal ganglia [nTPM]":"53.0","Tissue RNA - bone marrow [nTPM]":"95.9","Tissue RNA - breast [nTPM]":"76.3","Tissue RNA - cerebellum [nTPM]":"45.5","Tissue RNA - cerebral cortex [nTPM]":"54.8","Tissue RNA - cervix [nTPM]":"57.0","Tissue RNA - choroid plexus [nTPM]":"47.4","Tissue RNA - colon [nTPM]":"509.3","Tissue RNA - duodenum [nTPM]":"74.7","Tissue RNA - endometrium 1 [nTPM]":"31.3","Tissue RNA - epididymis [nTPM]":"43.4","Tissue RNA - esophagus [nTPM]":"31.8","Tissue RNA - fallopian tube [nTPM]":"132.7","Tissue RNA - gallbladder [nTPM]":"52.2","Tissue RNA - heart muscle [nTPM]":"69.1","Tissue RNA - hippocampal formation [nTPM]":"47.1","Tissue RNA - hypothalamus [nTPM]":"48.2","Tissue RNA - kidney [nTPM]":"77.2","Tissue RNA - liver [nTPM]":"261.7","Tissue RNA - lung [nTPM]":"181.0","Tissue RNA - lymph node [nTPM]":"10.9","Tissue RNA - medulla oblongata [nTPM]":"47.8","Tissue RNA - midbrain [nTPM]":"51.0","Tissue RNA - ovary [nTPM]":"49.4","Tissue RNA - pancreas [nTPM]":"29.0","Tissue RNA - parathyroid gland [nTPM]":"11.9","Tissue RNA - pituitary gland [nTPM]":"15.0","Tissue RNA - placenta [nTPM]":"20.4","Tissue RNA - pons [nTPM]":"46.5","Tissue RNA - prostate [nTPM]":"44.2","Tissue RNA - rectum [nTPM]":"471.7","Tissue RNA - retina [nTPM]":"3.9","Tissue RNA - salivary gland [nTPM]":"61.6","Tissue RNA - seminal vesicle [nTPM]":"48.8","Tissue RNA - skeletal muscle [nTPM]":"72.9","Tissue RNA - skin 1 [nTPM]":"25.2","Tissue RNA - small intestine [nTPM]":"94.2","Tissue RNA - smooth muscle [nTPM]":"49.5","Tissue RNA - spinal cord [nTPM]":"46.9","Tissue RNA - spleen [nTPM]":"51.1","Tissue RNA - stomach 1 [nTPM]":"126.4","Tissue RNA - testis [nTPM]":"6.1","Tissue RNA - thalamus [nTPM]":"51.0","Tissue RNA - thymus [nTPM]":"7.1","Tissue RNA - thyroid gland [nTPM]":"115.1","Tissue RNA - tongue [nTPM]":"138.1","Tissue RNA - tonsil [nTPM]":"6.8","Tissue RNA - urinary bladder [nTPM]":"58.3","Tissue RNA - vagina [nTPM]":"29.3","Tissue RNA - white matter [nTPM]":"45.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"17.2","Cell RNA - AF22 [nTPM]":"31.9","Cell RNA - AN3-CA [nTPM]":"1.8","Cell RNA - ASC diff [nTPM]":"144.9","Cell RNA - ASC TERT1 [nTPM]":"59.1","Cell RNA - BEWO [nTPM]":"8.4","Cell RNA - BJ [nTPM]":"5.9","Cell RNA - BJ hTERT+ [nTPM]":"2.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.5","Cell RNA - CACO-2 [nTPM]":"18.1","Cell RNA - CAPAN-2 [nTPM]":"5.4","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"30.7","Cell RNA - fHDF\/TERT166 [nTPM]":"10.7","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"2.8","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"14.8","Cell RNA - HEL [nTPM]":"120.5","Cell RNA - HeLa [nTPM]":"53.1","Cell RNA - Hep G2 [nTPM]":"28.9","Cell RNA - HHSteC [nTPM]":"30.5","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"75.9","Cell RNA - hTCEpi [nTPM]":"1.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.3","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.4","Cell RNA - HUVEC TERT2 [nTPM]":"19.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"12.4","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"8.0","Cell RNA - MCF7 [nTPM]":"13.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"26.6","Cell RNA - OE19 [nTPM]":"92.8","Cell RNA - PC-3 [nTPM]":"32.2","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"1.7","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"7.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.7","Cell RNA - SiHa [nTPM]":"0.5","Cell RNA - SK-BR-3 [nTPM]":"274.4","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"25.1","Cell RNA - T-47d [nTPM]":"49.4","Cell RNA - THP-1 [nTPM]":"1.8","Cell RNA - TIME [nTPM]":"1.8","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.1","Cell RNA - U-2197 [nTPM]":"16.8","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.6","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"2.4","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"2.2","Brain RNA - amygdala [nTPM]":"49.8","Brain RNA - basal ganglia [nTPM]":"53.0","Brain RNA - cerebellum [nTPM]":"45.5","Brain RNA - cerebral cortex [nTPM]":"54.8","Brain RNA - hippocampal formation [nTPM]":"47.1","Brain RNA - hypothalamus [nTPM]":"48.2","Brain RNA - medulla oblongata [nTPM]":"47.8","Brain RNA - midbrain [nTPM]":"51.0","Brain RNA - pons [nTPM]":"46.5","Brain RNA - spinal cord [nTPM]":"46.9","Brain RNA - thalamus [nTPM]":"51.0","Brain RNA - white matter [nTPM]":"45.7","Single Cell Type RNA - Adipocytes [nTPM]":"36.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"294.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"525.6","Single Cell Type RNA - Astrocytes [nTPM]":"38.2","Single Cell Type RNA - B-cells [nTPM]":"4.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"56.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"30.7","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"73.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"59.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"135.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"75.8","Single Cell Type RNA - Club cells [nTPM]":"123.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.4","Single Cell Type RNA - dendritic cells [nTPM]":"1.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"1056.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"115.4","Single Cell Type RNA - Ductal cells [nTPM]":"17.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"30.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.9","Single Cell Type RNA - Endothelial cells [nTPM]":"27.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"155.0","Single Cell Type RNA - Erythroid cells [nTPM]":"590.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.1","Single Cell Type RNA - Fibroblasts [nTPM]":"85.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"163.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.1","Single Cell Type RNA - granulocytes [nTPM]":"27.3","Single Cell Type RNA - Granulosa cells [nTPM]":"10.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.0","Single Cell Type RNA - Hepatocytes [nTPM]":"501.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"137.2","Single Cell Type RNA - Ionocytes [nTPM]":"79.3","Single Cell Type RNA - Kupffer cells [nTPM]":"39.6","Single Cell Type RNA - Langerhans cells [nTPM]":"12.4","Single Cell Type RNA - Late spermatids [nTPM]":"4.2","Single Cell Type RNA - Leydig cells [nTPM]":"66.5","Single Cell Type RNA - Macrophages [nTPM]":"3.9","Single Cell Type RNA - Melanocytes [nTPM]":"33.8","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"37.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.5","Single Cell Type RNA - Paneth cells [nTPM]":"451.4","Single Cell Type RNA - Peritubular cells [nTPM]":"80.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"25.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"251.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"148.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"101.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.4","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"102.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.0","Single Cell Type RNA - T-cells [nTPM]":"5.7","Single Cell Type RNA - Theca cells [nTPM]":"30.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"452.4","Single Cell Type RNA - Urothelial cells [nTPM]":"71.0"},{"Gene":"SELENOI","Gene synonym":["EPT1","KIAA1724","SELI","SEPI"],"Ensembl":"ENSG00000138018","Gene description":"Selenoprotein I","Uniprot":["Q9C0D9"],"Chromosome":"2","Position":"26308547-26395891","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"22.0","Endometrial ciliated cells":"16.3","Glandular and luminal cells":"15.3","Pancreatic endocrine cells":"13.6","Syncytiotrophoblasts":"16.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064125"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA064125":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.87e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.6","Tissue RNA - adrenal gland [nTPM]":"6.4","Tissue RNA - amygdala [nTPM]":"7.9","Tissue RNA - appendix [nTPM]":"5.5","Tissue RNA - basal ganglia [nTPM]":"8.4","Tissue RNA - bone marrow [nTPM]":"12.1","Tissue RNA - breast [nTPM]":"8.1","Tissue RNA - cerebellum [nTPM]":"11.2","Tissue RNA - cerebral cortex [nTPM]":"10.6","Tissue RNA - cervix [nTPM]":"5.4","Tissue RNA - choroid plexus [nTPM]":"5.0","Tissue RNA - colon [nTPM]":"8.6","Tissue RNA - duodenum [nTPM]":"12.3","Tissue RNA - endometrium 1 [nTPM]":"4.1","Tissue RNA - epididymis [nTPM]":"5.4","Tissue RNA - esophagus [nTPM]":"11.1","Tissue RNA - fallopian tube [nTPM]":"3.5","Tissue RNA - gallbladder [nTPM]":"4.0","Tissue RNA - heart muscle [nTPM]":"3.9","Tissue RNA - hippocampal formation [nTPM]":"10.3","Tissue RNA - hypothalamus [nTPM]":"9.3","Tissue RNA - kidney [nTPM]":"7.9","Tissue RNA - liver [nTPM]":"23.2","Tissue RNA - lung [nTPM]":"4.4","Tissue RNA - lymph node [nTPM]":"5.7","Tissue RNA - medulla oblongata [nTPM]":"6.8","Tissue RNA - midbrain [nTPM]":"7.3","Tissue RNA - ovary [nTPM]":"3.5","Tissue RNA - pancreas [nTPM]":"9.0","Tissue RNA - parathyroid gland [nTPM]":"17.2","Tissue RNA - pituitary gland [nTPM]":"4.5","Tissue RNA - placenta [nTPM]":"4.7","Tissue RNA - pons [nTPM]":"8.6","Tissue RNA - prostate [nTPM]":"6.2","Tissue RNA - rectum [nTPM]":"8.7","Tissue RNA - retina [nTPM]":"9.3","Tissue RNA - salivary gland [nTPM]":"6.2","Tissue RNA - seminal vesicle [nTPM]":"4.2","Tissue RNA - skeletal muscle [nTPM]":"7.0","Tissue RNA - skin 1 [nTPM]":"18.3","Tissue RNA - small intestine [nTPM]":"18.4","Tissue RNA - smooth muscle [nTPM]":"3.7","Tissue RNA - spinal cord [nTPM]":"9.7","Tissue RNA - spleen [nTPM]":"4.3","Tissue RNA - stomach 1 [nTPM]":"7.1","Tissue RNA - testis [nTPM]":"4.4","Tissue RNA - thalamus [nTPM]":"7.2","Tissue RNA - thymus [nTPM]":"6.3","Tissue RNA - thyroid gland [nTPM]":"7.1","Tissue RNA - tongue [nTPM]":"6.6","Tissue RNA - tonsil [nTPM]":"6.1","Tissue RNA - urinary bladder [nTPM]":"7.5","Tissue RNA - vagina [nTPM]":"7.1","Tissue RNA - white matter [nTPM]":"10.0","Cell RNA - A-431 [nTPM]":"42.7","Cell RNA - A549 [nTPM]":"25.7","Cell RNA - AF22 [nTPM]":"20.9","Cell RNA - AN3-CA [nTPM]":"21.0","Cell RNA - ASC diff [nTPM]":"12.8","Cell RNA - ASC TERT1 [nTPM]":"10.2","Cell RNA - BEWO [nTPM]":"32.0","Cell RNA - BJ [nTPM]":"20.3","Cell RNA - BJ hTERT+ [nTPM]":"9.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.2","Cell RNA - CACO-2 [nTPM]":"54.5","Cell RNA - CAPAN-2 [nTPM]":"26.6","Cell RNA - Daudi [nTPM]":"49.5","Cell RNA - EFO-21 [nTPM]":"24.2","Cell RNA - fHDF\/TERT166 [nTPM]":"9.5","Cell RNA - GAMG [nTPM]":"21.4","Cell RNA - HaCaT [nTPM]":"34.1","Cell RNA - HAP1 [nTPM]":"32.4","Cell RNA - HBEC3-KT [nTPM]":"17.9","Cell RNA - HBF TERT88 [nTPM]":"14.4","Cell RNA - HDLM-2 [nTPM]":"13.7","Cell RNA - HEK 293 [nTPM]":"15.4","Cell RNA - HEL [nTPM]":"31.3","Cell RNA - HeLa [nTPM]":"17.5","Cell RNA - Hep G2 [nTPM]":"32.3","Cell RNA - HHSteC [nTPM]":"12.2","Cell RNA - HL-60 [nTPM]":"41.9","Cell RNA - HMC-1 [nTPM]":"9.7","Cell RNA - HSkMC [nTPM]":"8.1","Cell RNA - hTCEpi [nTPM]":"15.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.3","Cell RNA - hTERT-HME1 [nTPM]":"21.9","Cell RNA - hTERT-RPE1 [nTPM]":"6.1","Cell RNA - HUVEC TERT2 [nTPM]":"9.4","Cell RNA - JURKAT [nTPM]":"17.6","Cell RNA - K-562 [nTPM]":"35.9","Cell RNA - Karpas-707 [nTPM]":"16.6","Cell RNA - LHCN-M2 [nTPM]":"13.5","Cell RNA - MCF7 [nTPM]":"18.4","Cell RNA - MOLT-4 [nTPM]":"25.1","Cell RNA - NB-4 [nTPM]":"20.7","Cell RNA - NTERA-2 [nTPM]":"26.8","Cell RNA - OE19 [nTPM]":"21.6","Cell RNA - PC-3 [nTPM]":"17.4","Cell RNA - REH [nTPM]":"22.6","Cell RNA - RH-30 [nTPM]":"49.2","Cell RNA - RPMI-8226 [nTPM]":"25.0","Cell RNA - RPTEC TERT1 [nTPM]":"19.3","Cell RNA - RT4 [nTPM]":"32.4","Cell RNA - SCLC-21H [nTPM]":"45.7","Cell RNA - SH-SY5Y [nTPM]":"19.4","Cell RNA - SiHa [nTPM]":"17.3","Cell RNA - SK-BR-3 [nTPM]":"36.2","Cell RNA - SK-MEL-30 [nTPM]":"16.4","Cell RNA - SuSa [nTPM]":"17.3","Cell RNA - T-47d [nTPM]":"17.4","Cell RNA - THP-1 [nTPM]":"12.4","Cell RNA - TIME [nTPM]":"15.1","Cell RNA - U-138 MG [nTPM]":"17.1","Cell RNA - U-2 OS [nTPM]":"22.0","Cell RNA - U-2197 [nTPM]":"22.7","Cell RNA - U-251 MG [nTPM]":"31.7","Cell RNA - U-266\/70 [nTPM]":"22.6","Cell RNA - U-266\/84 [nTPM]":"60.8","Cell RNA - U-698 [nTPM]":"65.8","Cell RNA - U-87 MG [nTPM]":"17.5","Cell RNA - U-937 [nTPM]":"25.4","Cell RNA - WM-115 [nTPM]":"15.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.7","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.9","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"0.9","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.2","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"2.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.9","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"1.8","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"7.9","Brain RNA - basal ganglia [nTPM]":"8.4","Brain RNA - cerebellum [nTPM]":"11.2","Brain RNA - cerebral cortex [nTPM]":"10.6","Brain RNA - hippocampal formation [nTPM]":"10.3","Brain RNA - hypothalamus [nTPM]":"9.3","Brain RNA - medulla oblongata [nTPM]":"6.8","Brain RNA - midbrain [nTPM]":"7.3","Brain RNA - pons [nTPM]":"8.6","Brain RNA - spinal cord [nTPM]":"9.7","Brain RNA - thalamus [nTPM]":"7.2","Brain RNA - white matter [nTPM]":"10.0","Single Cell Type RNA - Adipocytes [nTPM]":"9.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"3.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.1","Single Cell Type RNA - dendritic cells [nTPM]":"11.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"10.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.8","Single Cell Type RNA - Endothelial cells [nTPM]":"3.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.2","Single Cell Type RNA - Fibroblasts [nTPM]":"2.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.3","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"8.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"3.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"3.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.6","Single Cell Type RNA - T-cells [nTPM]":"4.7","Single Cell Type RNA - Theca cells [nTPM]":"11.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SELENOT","Gene synonym":["SELT"],"Ensembl":"ENSG00000198843","Gene description":"Selenoprotein T","Uniprot":["P62341"],"Chromosome":"3","Position":"150602875-150630445","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"215.1","Extravillous trophoblasts":"230.6","Hofbauer cells":"238.8","Pancreatic endocrine cells":"206.0","Proximal tubular cells":"176.8","Syncytiotrophoblasts":"489.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039780"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039780":"AB_10805594"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-2"},"Tissue RNA - adipose tissue [nTPM]":"49.2","Tissue RNA - adrenal gland [nTPM]":"73.5","Tissue RNA - amygdala [nTPM]":"44.0","Tissue RNA - appendix [nTPM]":"56.4","Tissue RNA - basal ganglia [nTPM]":"47.2","Tissue RNA - bone marrow [nTPM]":"100.0","Tissue RNA - breast [nTPM]":"47.8","Tissue RNA - cerebellum [nTPM]":"49.8","Tissue RNA - cerebral cortex [nTPM]":"58.9","Tissue RNA - cervix [nTPM]":"44.0","Tissue RNA - choroid plexus [nTPM]":"44.8","Tissue RNA - colon [nTPM]":"49.1","Tissue RNA - duodenum [nTPM]":"51.2","Tissue RNA - endometrium 1 [nTPM]":"39.2","Tissue RNA - epididymis [nTPM]":"62.7","Tissue RNA - esophagus [nTPM]":"41.0","Tissue RNA - fallopian tube [nTPM]":"49.1","Tissue RNA - gallbladder [nTPM]":"38.9","Tissue RNA - heart muscle [nTPM]":"51.9","Tissue RNA - hippocampal formation [nTPM]":"46.0","Tissue RNA - hypothalamus [nTPM]":"52.2","Tissue RNA - kidney [nTPM]":"75.4","Tissue RNA - liver [nTPM]":"72.4","Tissue RNA - lung [nTPM]":"51.0","Tissue RNA - lymph node [nTPM]":"80.5","Tissue RNA - medulla oblongata [nTPM]":"46.9","Tissue RNA - midbrain [nTPM]":"46.9","Tissue RNA - ovary [nTPM]":"36.0","Tissue RNA - pancreas [nTPM]":"45.4","Tissue RNA - parathyroid gland [nTPM]":"84.2","Tissue RNA - pituitary gland [nTPM]":"45.6","Tissue RNA - placenta [nTPM]":"60.6","Tissue RNA - pons [nTPM]":"49.9","Tissue RNA - prostate [nTPM]":"49.5","Tissue RNA - rectum [nTPM]":"56.6","Tissue RNA - retina [nTPM]":"69.7","Tissue RNA - salivary gland [nTPM]":"45.5","Tissue RNA - seminal vesicle [nTPM]":"48.8","Tissue RNA - skeletal muscle [nTPM]":"44.9","Tissue RNA - skin 1 [nTPM]":"28.3","Tissue RNA - small intestine [nTPM]":"50.3","Tissue RNA - smooth muscle [nTPM]":"54.1","Tissue RNA - spinal cord [nTPM]":"50.5","Tissue RNA - spleen [nTPM]":"46.4","Tissue RNA - stomach 1 [nTPM]":"45.1","Tissue RNA - testis [nTPM]":"39.7","Tissue RNA - thalamus [nTPM]":"47.7","Tissue RNA - thymus [nTPM]":"58.3","Tissue RNA - thyroid gland [nTPM]":"67.2","Tissue RNA - tongue [nTPM]":"54.0","Tissue RNA - tonsil [nTPM]":"73.2","Tissue RNA - urinary bladder [nTPM]":"63.4","Tissue RNA - vagina [nTPM]":"32.0","Tissue RNA - white matter [nTPM]":"53.9","Cell RNA - A-431 [nTPM]":"232.1","Cell RNA - A549 [nTPM]":"94.9","Cell RNA - AF22 [nTPM]":"57.1","Cell RNA - AN3-CA [nTPM]":"51.8","Cell RNA - ASC diff [nTPM]":"86.7","Cell RNA - ASC TERT1 [nTPM]":"84.0","Cell RNA - BEWO [nTPM]":"111.3","Cell RNA - BJ [nTPM]":"174.3","Cell RNA - BJ hTERT+ [nTPM]":"127.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"120.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"79.6","Cell RNA - CACO-2 [nTPM]":"145.9","Cell RNA - CAPAN-2 [nTPM]":"129.1","Cell RNA - Daudi [nTPM]":"125.6","Cell RNA - EFO-21 [nTPM]":"192.2","Cell RNA - fHDF\/TERT166 [nTPM]":"128.7","Cell RNA - GAMG [nTPM]":"107.5","Cell RNA - HaCaT [nTPM]":"76.1","Cell RNA - HAP1 [nTPM]":"89.6","Cell RNA - HBEC3-KT [nTPM]":"110.3","Cell RNA - HBF TERT88 [nTPM]":"177.7","Cell RNA - HDLM-2 [nTPM]":"124.8","Cell RNA - HEK 293 [nTPM]":"77.3","Cell RNA - HEL [nTPM]":"130.9","Cell RNA - HeLa [nTPM]":"48.4","Cell RNA - Hep G2 [nTPM]":"68.1","Cell RNA - HHSteC [nTPM]":"94.6","Cell RNA - HL-60 [nTPM]":"77.1","Cell RNA - HMC-1 [nTPM]":"102.5","Cell RNA - HSkMC [nTPM]":"74.1","Cell RNA - hTCEpi [nTPM]":"86.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"107.6","Cell RNA - hTERT-HME1 [nTPM]":"92.1","Cell RNA - hTERT-RPE1 [nTPM]":"86.7","Cell RNA - HUVEC TERT2 [nTPM]":"132.2","Cell RNA - JURKAT [nTPM]":"58.2","Cell RNA - K-562 [nTPM]":"31.0","Cell RNA - Karpas-707 [nTPM]":"359.9","Cell RNA - LHCN-M2 [nTPM]":"173.4","Cell RNA - MCF7 [nTPM]":"137.6","Cell RNA - MOLT-4 [nTPM]":"107.5","Cell RNA - NB-4 [nTPM]":"46.1","Cell RNA - NTERA-2 [nTPM]":"65.4","Cell RNA - OE19 [nTPM]":"134.2","Cell RNA - PC-3 [nTPM]":"99.0","Cell RNA - REH [nTPM]":"79.0","Cell RNA - RH-30 [nTPM]":"73.8","Cell RNA - RPMI-8226 [nTPM]":"215.4","Cell RNA - RPTEC TERT1 [nTPM]":"102.6","Cell RNA - RT4 [nTPM]":"132.7","Cell RNA - SCLC-21H [nTPM]":"64.2","Cell RNA - SH-SY5Y [nTPM]":"39.8","Cell RNA - SiHa [nTPM]":"106.4","Cell RNA - SK-BR-3 [nTPM]":"64.4","Cell RNA - SK-MEL-30 [nTPM]":"74.8","Cell RNA - SuSa [nTPM]":"71.2","Cell RNA - T-47d [nTPM]":"133.6","Cell RNA - THP-1 [nTPM]":"96.2","Cell RNA - TIME [nTPM]":"125.7","Cell RNA - U-138 MG [nTPM]":"65.1","Cell RNA - U-2 OS [nTPM]":"41.1","Cell RNA - U-2197 [nTPM]":"121.1","Cell RNA - U-251 MG [nTPM]":"172.6","Cell RNA - U-266\/70 [nTPM]":"261.3","Cell RNA - U-266\/84 [nTPM]":"151.4","Cell RNA - U-698 [nTPM]":"176.1","Cell RNA - U-87 MG [nTPM]":"88.8","Cell RNA - U-937 [nTPM]":"142.1","Cell RNA - WM-115 [nTPM]":"56.9","Blood RNA - basophil [nTPM]":"218.1","Blood RNA - classical monocyte [nTPM]":"163.8","Blood RNA - eosinophil [nTPM]":"142.5","Blood RNA - gdT-cell [nTPM]":"133.7","Blood RNA - intermediate monocyte [nTPM]":"138.4","Blood RNA - MAIT T-cell [nTPM]":"148.5","Blood RNA - memory B-cell [nTPM]":"119.6","Blood RNA - memory CD4 T-cell [nTPM]":"111.3","Blood RNA - memory CD8 T-cell [nTPM]":"125.4","Blood RNA - myeloid DC [nTPM]":"126.5","Blood RNA - naive B-cell [nTPM]":"102.3","Blood RNA - naive CD4 T-cell [nTPM]":"87.4","Blood RNA - naive CD8 T-cell [nTPM]":"110.1","Blood RNA - neutrophil [nTPM]":"198.8","Blood RNA - NK-cell [nTPM]":"106.3","Blood RNA - non-classical monocyte [nTPM]":"155.7","Blood RNA - plasmacytoid DC [nTPM]":"90.7","Blood RNA - T-reg [nTPM]":"132.3","Blood RNA - total PBMC [nTPM]":"324.7","Brain RNA - amygdala [nTPM]":"44.0","Brain RNA - basal ganglia [nTPM]":"47.2","Brain RNA - cerebellum [nTPM]":"49.8","Brain RNA - cerebral cortex [nTPM]":"58.9","Brain RNA - hippocampal formation [nTPM]":"46.0","Brain RNA - hypothalamus [nTPM]":"52.2","Brain RNA - medulla oblongata [nTPM]":"46.9","Brain RNA - midbrain [nTPM]":"46.9","Brain RNA - pons [nTPM]":"49.9","Brain RNA - spinal cord [nTPM]":"50.5","Brain RNA - thalamus [nTPM]":"47.7","Brain RNA - white matter [nTPM]":"53.9","Single Cell Type RNA - Adipocytes [nTPM]":"80.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"67.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"53.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"97.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"66.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"29.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"108.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"215.1","Single Cell Type RNA - dendritic cells [nTPM]":"114.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"97.8","Single Cell Type RNA - Ductal cells [nTPM]":"166.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"63.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"46.8","Single Cell Type RNA - Endothelial cells [nTPM]":"35.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"135.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"230.6","Single Cell Type RNA - Fibroblasts [nTPM]":"30.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"64.7","Single Cell Type RNA - granulocytes [nTPM]":"45.4","Single Cell Type RNA - Granulosa cells [nTPM]":"31.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"238.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"72.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"123.5","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"206.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"21.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"176.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"32.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"37.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"489.3","Single Cell Type RNA - T-cells [nTPM]":"48.1","Single Cell Type RNA - Theca cells [nTPM]":"63.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SEPSECS","Gene synonym":["SLA","SLA\/LP"],"Ensembl":"ENSG00000109618","Gene description":"Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase","Uniprot":["Q9HD40"],"Chromosome":"4","Position":"25120014-25160550","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["RNA-binding","Transferase","tRNA-binding"],"Disease involvement":["Disease variant","Epilepsy","Mental retardation","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"26.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"42.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070409"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA070409":"AB_2686265"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-3"},"Tissue RNA - adipose tissue [nTPM]":"4.7","Tissue RNA - adrenal gland [nTPM]":"3.5","Tissue RNA - amygdala [nTPM]":"2.1","Tissue RNA - appendix [nTPM]":"1.7","Tissue RNA - basal ganglia [nTPM]":"2.1","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"4.4","Tissue RNA - cerebellum [nTPM]":"2.0","Tissue RNA - cerebral cortex [nTPM]":"3.0","Tissue RNA - cervix [nTPM]":"4.2","Tissue RNA - choroid plexus [nTPM]":"1.6","Tissue RNA - colon [nTPM]":"5.3","Tissue RNA - duodenum [nTPM]":"4.8","Tissue RNA - endometrium 1 [nTPM]":"3.8","Tissue RNA - epididymis [nTPM]":"2.6","Tissue RNA - esophagus [nTPM]":"3.2","Tissue RNA - fallopian tube [nTPM]":"3.8","Tissue RNA - gallbladder [nTPM]":"2.5","Tissue RNA - heart muscle [nTPM]":"2.7","Tissue RNA - hippocampal formation [nTPM]":"2.0","Tissue RNA - hypothalamus [nTPM]":"2.1","Tissue RNA - kidney [nTPM]":"8.2","Tissue RNA - liver [nTPM]":"26.1","Tissue RNA - lung [nTPM]":"3.9","Tissue RNA - lymph node [nTPM]":"2.1","Tissue RNA - medulla oblongata [nTPM]":"2.2","Tissue RNA - midbrain [nTPM]":"2.0","Tissue RNA - ovary [nTPM]":"4.9","Tissue RNA - pancreas [nTPM]":"7.4","Tissue RNA - parathyroid gland [nTPM]":"3.3","Tissue RNA - pituitary gland [nTPM]":"3.0","Tissue RNA - placenta [nTPM]":"2.8","Tissue RNA - pons [nTPM]":"2.1","Tissue RNA - prostate [nTPM]":"3.4","Tissue RNA - rectum [nTPM]":"2.7","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"3.9","Tissue RNA - seminal vesicle [nTPM]":"2.0","Tissue RNA - skeletal muscle [nTPM]":"3.4","Tissue RNA - skin 1 [nTPM]":"5.2","Tissue RNA - small intestine [nTPM]":"7.6","Tissue RNA - smooth muscle [nTPM]":"1.3","Tissue RNA - spinal cord [nTPM]":"2.0","Tissue RNA - spleen [nTPM]":"5.6","Tissue RNA - stomach 1 [nTPM]":"5.0","Tissue RNA - testis [nTPM]":"4.0","Tissue RNA - thalamus [nTPM]":"2.1","Tissue RNA - thymus [nTPM]":"5.2","Tissue RNA - thyroid gland [nTPM]":"4.8","Tissue RNA - tongue [nTPM]":"2.6","Tissue RNA - tonsil [nTPM]":"2.0","Tissue RNA - urinary bladder [nTPM]":"3.8","Tissue RNA - vagina [nTPM]":"3.5","Tissue RNA - white matter [nTPM]":"2.3","Cell RNA - A-431 [nTPM]":"1.7","Cell RNA - A549 [nTPM]":"1.0","Cell RNA - AF22 [nTPM]":"3.0","Cell RNA - AN3-CA [nTPM]":"1.3","Cell RNA - ASC diff [nTPM]":"3.9","Cell RNA - ASC TERT1 [nTPM]":"4.9","Cell RNA - BEWO [nTPM]":"2.5","Cell RNA - BJ [nTPM]":"1.1","Cell RNA - BJ hTERT+ [nTPM]":"1.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.3","Cell RNA - CACO-2 [nTPM]":"0.6","Cell RNA - CAPAN-2 [nTPM]":"2.6","Cell RNA - Daudi [nTPM]":"2.9","Cell RNA - EFO-21 [nTPM]":"1.4","Cell RNA - fHDF\/TERT166 [nTPM]":"1.0","Cell RNA - GAMG [nTPM]":"2.6","Cell RNA - HaCaT [nTPM]":"1.3","Cell RNA - HAP1 [nTPM]":"3.5","Cell RNA - HBEC3-KT [nTPM]":"1.2","Cell RNA - HBF TERT88 [nTPM]":"2.0","Cell RNA - HDLM-2 [nTPM]":"1.9","Cell RNA - HEK 293 [nTPM]":"1.3","Cell RNA - HEL [nTPM]":"2.5","Cell RNA - HeLa [nTPM]":"1.0","Cell RNA - Hep G2 [nTPM]":"1.8","Cell RNA - HHSteC [nTPM]":"4.0","Cell RNA - HL-60 [nTPM]":"2.0","Cell RNA - HMC-1 [nTPM]":"3.3","Cell RNA - HSkMC [nTPM]":"4.0","Cell RNA - hTCEpi [nTPM]":"4.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.0","Cell RNA - hTERT-HME1 [nTPM]":"3.7","Cell RNA - hTERT-RPE1 [nTPM]":"3.1","Cell RNA - HUVEC TERT2 [nTPM]":"2.5","Cell RNA - JURKAT [nTPM]":"4.3","Cell RNA - K-562 [nTPM]":"7.0","Cell RNA - Karpas-707 [nTPM]":"2.5","Cell RNA - LHCN-M2 [nTPM]":"1.6","Cell RNA - MCF7 [nTPM]":"0.7","Cell RNA - MOLT-4 [nTPM]":"4.4","Cell RNA - NB-4 [nTPM]":"6.2","Cell RNA - NTERA-2 [nTPM]":"2.1","Cell RNA - OE19 [nTPM]":"1.8","Cell RNA - PC-3 [nTPM]":"2.5","Cell RNA - REH [nTPM]":"1.3","Cell RNA - RH-30 [nTPM]":"4.3","Cell RNA - RPMI-8226 [nTPM]":"1.7","Cell RNA - RPTEC TERT1 [nTPM]":"3.7","Cell RNA - RT4 [nTPM]":"0.7","Cell RNA - SCLC-21H [nTPM]":"1.6","Cell RNA - SH-SY5Y [nTPM]":"2.4","Cell RNA - SiHa [nTPM]":"1.3","Cell RNA - SK-BR-3 [nTPM]":"1.4","Cell RNA - SK-MEL-30 [nTPM]":"4.7","Cell RNA - SuSa [nTPM]":"1.9","Cell RNA - T-47d [nTPM]":"1.5","Cell RNA - THP-1 [nTPM]":"5.5","Cell RNA - TIME [nTPM]":"1.0","Cell RNA - U-138 MG [nTPM]":"1.4","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"0.7","Cell RNA - U-251 MG [nTPM]":"1.7","Cell RNA - U-266\/70 [nTPM]":"2.3","Cell RNA - U-266\/84 [nTPM]":"6.2","Cell RNA - U-698 [nTPM]":"1.6","Cell RNA - U-87 MG [nTPM]":"1.4","Cell RNA - U-937 [nTPM]":"5.4","Cell RNA - WM-115 [nTPM]":"1.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"2.1","Brain RNA - basal ganglia [nTPM]":"2.1","Brain RNA - cerebellum [nTPM]":"2.0","Brain RNA - cerebral cortex [nTPM]":"3.0","Brain RNA - hippocampal formation [nTPM]":"2.0","Brain RNA - hypothalamus [nTPM]":"2.1","Brain RNA - medulla oblongata [nTPM]":"2.2","Brain RNA - midbrain [nTPM]":"2.0","Brain RNA - pons [nTPM]":"2.1","Brain RNA - spinal cord [nTPM]":"2.0","Brain RNA - thalamus [nTPM]":"2.1","Brain RNA - white matter [nTPM]":"2.3","Single Cell Type RNA - Adipocytes [nTPM]":"5.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.2","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"6.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"3.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"4.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.5","Single Cell Type RNA - dendritic cells [nTPM]":"4.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.4","Single Cell Type RNA - Early spermatids [nTPM]":"30.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.2","Single Cell Type RNA - Endothelial cells [nTPM]":"6.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.1","Single Cell Type RNA - Erythroid cells [nTPM]":"8.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.5","Single Cell Type RNA - Fibroblasts [nTPM]":"4.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.4","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"7.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"42.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.1","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.7","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"8.1","Single Cell Type RNA - Langerhans cells [nTPM]":"4.5","Single Cell Type RNA - Late spermatids [nTPM]":"18.1","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"6.6","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"8.0","Single Cell Type RNA - Muller glia cells [nTPM]":"3.2","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.4","Single Cell Type RNA - Paneth cells [nTPM]":"6.0","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"6.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"20.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.4","Single Cell Type RNA - Spermatocytes [nTPM]":"26.0","Single Cell Type RNA - Spermatogonia [nTPM]":"18.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.9","Single Cell Type RNA - T-cells [nTPM]":"6.2","Single Cell Type RNA - Theca cells [nTPM]":"7.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.8","Single Cell Type RNA - Urothelial cells [nTPM]":"1.1"},{"Gene":"SETD1A","Gene synonym":["KIAA0339","KMT2F","Set1"],"Ensembl":"ENSG00000099381","Gene description":"SET domain containing 1A, histone lysine methyltransferase","Uniprot":["O15047"],"Chromosome":"16","Position":"30957754-30984664","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","Chromatin regulator","Methyltransferase","RNA-binding","Transferase"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020646","HPA058376"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA020646":"AB_1856752","HPA058376":"AB_2683695"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.47e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.2","Tissue RNA - adrenal gland [nTPM]":"10.0","Tissue RNA - amygdala [nTPM]":"6.0","Tissue RNA - appendix [nTPM]":"7.3","Tissue RNA - basal ganglia [nTPM]":"5.5","Tissue RNA - bone marrow [nTPM]":"20.1","Tissue RNA - breast [nTPM]":"10.0","Tissue RNA - cerebellum [nTPM]":"8.4","Tissue RNA - cerebral cortex [nTPM]":"8.3","Tissue RNA - cervix [nTPM]":"11.0","Tissue RNA - choroid plexus [nTPM]":"3.0","Tissue RNA - colon [nTPM]":"13.0","Tissue RNA - duodenum [nTPM]":"6.6","Tissue RNA - endometrium 1 [nTPM]":"13.0","Tissue RNA - epididymis [nTPM]":"2.8","Tissue RNA - esophagus [nTPM]":"9.0","Tissue RNA - fallopian tube [nTPM]":"10.5","Tissue RNA - gallbladder [nTPM]":"4.1","Tissue RNA - heart muscle [nTPM]":"8.5","Tissue RNA - hippocampal formation [nTPM]":"5.5","Tissue RNA - hypothalamus [nTPM]":"5.5","Tissue RNA - kidney [nTPM]":"8.4","Tissue RNA - liver [nTPM]":"10.4","Tissue RNA - lung [nTPM]":"8.2","Tissue RNA - lymph node [nTPM]":"8.6","Tissue RNA - medulla oblongata [nTPM]":"5.6","Tissue RNA - midbrain [nTPM]":"5.4","Tissue RNA - ovary [nTPM]":"12.4","Tissue RNA - pancreas [nTPM]":"10.6","Tissue RNA - parathyroid gland [nTPM]":"8.0","Tissue RNA - pituitary gland [nTPM]":"11.9","Tissue RNA - placenta [nTPM]":"5.0","Tissue RNA - pons [nTPM]":"5.4","Tissue RNA - prostate [nTPM]":"10.2","Tissue RNA - rectum [nTPM]":"3.3","Tissue RNA - retina [nTPM]":"3.1","Tissue RNA - salivary gland [nTPM]":"9.3","Tissue RNA - seminal vesicle [nTPM]":"6.1","Tissue RNA - skeletal muscle [nTPM]":"15.1","Tissue RNA - skin 1 [nTPM]":"12.3","Tissue RNA - small intestine [nTPM]":"10.5","Tissue RNA - smooth muscle [nTPM]":"6.3","Tissue RNA - spinal cord [nTPM]":"4.1","Tissue RNA - spleen [nTPM]":"11.8","Tissue RNA - stomach 1 [nTPM]":"10.0","Tissue RNA - testis [nTPM]":"20.8","Tissue RNA - thalamus [nTPM]":"6.0","Tissue RNA - thymus [nTPM]":"10.0","Tissue RNA - thyroid gland [nTPM]":"11.8","Tissue RNA - tongue [nTPM]":"7.1","Tissue RNA - tonsil [nTPM]":"5.1","Tissue RNA - urinary bladder [nTPM]":"10.2","Tissue RNA - vagina [nTPM]":"9.3","Tissue RNA - white matter [nTPM]":"6.9","Cell RNA - A-431 [nTPM]":"13.1","Cell RNA - A549 [nTPM]":"24.4","Cell RNA - AF22 [nTPM]":"15.9","Cell RNA - AN3-CA [nTPM]":"19.4","Cell RNA - ASC diff [nTPM]":"8.7","Cell RNA - ASC TERT1 [nTPM]":"6.3","Cell RNA - BEWO [nTPM]":"18.0","Cell RNA - BJ [nTPM]":"13.6","Cell RNA - BJ hTERT+ [nTPM]":"10.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.1","Cell RNA - CACO-2 [nTPM]":"20.2","Cell RNA - CAPAN-2 [nTPM]":"12.8","Cell RNA - Daudi [nTPM]":"34.2","Cell RNA - EFO-21 [nTPM]":"15.2","Cell RNA - fHDF\/TERT166 [nTPM]":"13.0","Cell RNA - GAMG [nTPM]":"12.0","Cell RNA - HaCaT [nTPM]":"16.4","Cell RNA - HAP1 [nTPM]":"15.0","Cell RNA - HBEC3-KT [nTPM]":"14.6","Cell RNA - HBF TERT88 [nTPM]":"9.3","Cell RNA - HDLM-2 [nTPM]":"18.5","Cell RNA - HEK 293 [nTPM]":"56.1","Cell RNA - HEL [nTPM]":"16.0","Cell RNA - HeLa [nTPM]":"47.1","Cell RNA - Hep G2 [nTPM]":"23.2","Cell RNA - HHSteC [nTPM]":"8.9","Cell RNA - HL-60 [nTPM]":"26.6","Cell RNA - HMC-1 [nTPM]":"26.2","Cell RNA - HSkMC [nTPM]":"11.0","Cell RNA - hTCEpi [nTPM]":"11.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"17.1","Cell RNA - hTERT-HME1 [nTPM]":"10.8","Cell RNA - hTERT-RPE1 [nTPM]":"9.2","Cell RNA - HUVEC TERT2 [nTPM]":"9.3","Cell RNA - JURKAT [nTPM]":"19.5","Cell RNA - K-562 [nTPM]":"32.3","Cell RNA - Karpas-707 [nTPM]":"19.0","Cell RNA - LHCN-M2 [nTPM]":"6.4","Cell RNA - MCF7 [nTPM]":"27.2","Cell RNA - MOLT-4 [nTPM]":"32.3","Cell RNA - NB-4 [nTPM]":"27.7","Cell RNA - NTERA-2 [nTPM]":"23.4","Cell RNA - OE19 [nTPM]":"9.0","Cell RNA - PC-3 [nTPM]":"15.4","Cell RNA - REH [nTPM]":"48.7","Cell RNA - RH-30 [nTPM]":"15.9","Cell RNA - RPMI-8226 [nTPM]":"21.9","Cell RNA - RPTEC TERT1 [nTPM]":"7.6","Cell RNA - RT4 [nTPM]":"13.9","Cell RNA - SCLC-21H [nTPM]":"17.6","Cell RNA - SH-SY5Y [nTPM]":"18.1","Cell RNA - SiHa [nTPM]":"18.7","Cell RNA - SK-BR-3 [nTPM]":"15.1","Cell RNA - SK-MEL-30 [nTPM]":"10.8","Cell RNA - SuSa [nTPM]":"8.7","Cell RNA - T-47d [nTPM]":"16.2","Cell RNA - THP-1 [nTPM]":"22.1","Cell RNA - TIME [nTPM]":"12.8","Cell RNA - U-138 MG [nTPM]":"17.7","Cell RNA - U-2 OS [nTPM]":"17.1","Cell RNA - U-2197 [nTPM]":"11.6","Cell RNA - U-251 MG [nTPM]":"14.9","Cell RNA - U-266\/70 [nTPM]":"28.0","Cell RNA - U-266\/84 [nTPM]":"36.2","Cell RNA - U-698 [nTPM]":"32.4","Cell RNA - U-87 MG [nTPM]":"14.3","Cell RNA - U-937 [nTPM]":"22.9","Cell RNA - WM-115 [nTPM]":"13.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"6.0","Brain RNA - basal ganglia [nTPM]":"5.5","Brain RNA - cerebellum [nTPM]":"8.4","Brain RNA - cerebral cortex [nTPM]":"8.3","Brain RNA - hippocampal formation [nTPM]":"5.5","Brain RNA - hypothalamus [nTPM]":"5.5","Brain RNA - medulla oblongata [nTPM]":"5.6","Brain RNA - midbrain [nTPM]":"5.4","Brain RNA - pons [nTPM]":"5.4","Brain RNA - spinal cord [nTPM]":"4.1","Brain RNA - thalamus [nTPM]":"6.0","Brain RNA - white matter [nTPM]":"6.9","Single Cell Type RNA - Adipocytes [nTPM]":"7.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.2","Single Cell Type RNA - Astrocytes [nTPM]":"9.1","Single Cell Type RNA - B-cells [nTPM]":"8.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Bipolar cells [nTPM]":"8.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"4.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.6","Single Cell Type RNA - dendritic cells [nTPM]":"11.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"4.2","Single Cell Type RNA - Early spermatids [nTPM]":"3.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.2","Single Cell Type RNA - Endothelial cells [nTPM]":"9.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.3","Single Cell Type RNA - Erythroid cells [nTPM]":"6.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.7","Single Cell Type RNA - Fibroblasts [nTPM]":"7.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.6","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"9.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"9.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.5","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.9","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.7","Single Cell Type RNA - Langerhans cells [nTPM]":"7.1","Single Cell Type RNA - Late spermatids [nTPM]":"2.9","Single Cell Type RNA - Leydig cells [nTPM]":"9.9","Single Cell Type RNA - Macrophages [nTPM]":"5.5","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"4.7","Single Cell Type RNA - Muller glia cells [nTPM]":"4.8","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.4","Single Cell Type RNA - Paneth cells [nTPM]":"4.8","Single Cell Type RNA - Peritubular cells [nTPM]":"11.7","Single Cell Type RNA - Plasma cells [nTPM]":"7.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.8","Single Cell Type RNA - Spermatocytes [nTPM]":"17.5","Single Cell Type RNA - Spermatogonia [nTPM]":"23.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.9","Single Cell Type RNA - T-cells [nTPM]":"8.6","Single Cell Type RNA - Theca cells [nTPM]":"10.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.9","Single Cell Type RNA - Urothelial cells [nTPM]":"4.8"},{"Gene":"SETD2","Gene synonym":["FLJ23184","HIF-1","HYPB","KIAA1732","KMT3A"],"Ensembl":"ENSG00000181555","Gene description":"SET domain containing 2, histone lysine methyltransferase","Uniprot":["Q9BYW2"],"Chromosome":"3","Position":"47016429-47164113","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Antiviral defense","Differentiation","DNA damage","DNA repair","Host-virus interaction","Immunity","Innate immunity","Transcription","Transcription regulation"],"Molecular function":["Activator","Chromatin regulator","Developmental protein","Methyltransferase","Transferase"],"Disease involvement":["Autism spectrum disorder","Cancer-related genes","Disease variant","Mental retardation","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042451"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA042451":"AB_10806239"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.19e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.99e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.9","Tissue RNA - adrenal gland [nTPM]":"6.5","Tissue RNA - amygdala [nTPM]":"8.2","Tissue RNA - appendix [nTPM]":"10.7","Tissue RNA - basal ganglia [nTPM]":"10.5","Tissue RNA - bone marrow [nTPM]":"23.8","Tissue RNA - breast [nTPM]":"10.3","Tissue RNA - cerebellum [nTPM]":"24.1","Tissue RNA - cerebral cortex [nTPM]":"8.3","Tissue RNA - cervix [nTPM]":"12.6","Tissue RNA - choroid plexus [nTPM]":"10.8","Tissue RNA - colon [nTPM]":"9.7","Tissue RNA - duodenum [nTPM]":"9.1","Tissue RNA - endometrium 1 [nTPM]":"13.3","Tissue RNA - epididymis [nTPM]":"6.1","Tissue RNA - esophagus [nTPM]":"9.8","Tissue RNA - fallopian tube [nTPM]":"11.0","Tissue RNA - gallbladder [nTPM]":"8.5","Tissue RNA - heart muscle [nTPM]":"7.2","Tissue RNA - hippocampal formation [nTPM]":"6.2","Tissue RNA - hypothalamus [nTPM]":"6.7","Tissue RNA - kidney [nTPM]":"10.8","Tissue RNA - liver [nTPM]":"10.0","Tissue RNA - lung [nTPM]":"9.4","Tissue RNA - lymph node [nTPM]":"13.5","Tissue RNA - medulla oblongata [nTPM]":"8.3","Tissue RNA - midbrain [nTPM]":"8.5","Tissue RNA - ovary [nTPM]":"15.3","Tissue RNA - pancreas [nTPM]":"13.3","Tissue RNA - parathyroid gland [nTPM]":"16.2","Tissue RNA - pituitary gland [nTPM]":"2.2","Tissue RNA - placenta [nTPM]":"11.4","Tissue RNA - pons [nTPM]":"8.4","Tissue RNA - prostate [nTPM]":"10.2","Tissue RNA - rectum [nTPM]":"11.0","Tissue RNA - retina [nTPM]":"10.6","Tissue RNA - salivary gland [nTPM]":"9.6","Tissue RNA - seminal vesicle [nTPM]":"9.7","Tissue RNA - skeletal muscle [nTPM]":"11.1","Tissue RNA - skin 1 [nTPM]":"9.0","Tissue RNA - small intestine [nTPM]":"10.3","Tissue RNA - smooth muscle [nTPM]":"11.9","Tissue RNA - spinal cord [nTPM]":"8.1","Tissue RNA - spleen [nTPM]":"11.4","Tissue RNA - stomach 1 [nTPM]":"10.7","Tissue RNA - testis [nTPM]":"13.1","Tissue RNA - thalamus [nTPM]":"7.9","Tissue RNA - thymus [nTPM]":"19.2","Tissue RNA - thyroid gland [nTPM]":"15.5","Tissue RNA - tongue [nTPM]":"14.5","Tissue RNA - tonsil [nTPM]":"13.3","Tissue RNA - urinary bladder [nTPM]":"9.8","Tissue RNA - vagina [nTPM]":"4.0","Tissue RNA - white matter [nTPM]":"12.8","Cell RNA - A-431 [nTPM]":"21.1","Cell RNA - A549 [nTPM]":"13.2","Cell RNA - AF22 [nTPM]":"25.4","Cell RNA - AN3-CA [nTPM]":"14.5","Cell RNA - ASC diff [nTPM]":"15.3","Cell RNA - ASC TERT1 [nTPM]":"18.9","Cell RNA - BEWO [nTPM]":"11.3","Cell RNA - BJ [nTPM]":"17.9","Cell RNA - BJ hTERT+ [nTPM]":"17.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.9","Cell RNA - CACO-2 [nTPM]":"15.4","Cell RNA - CAPAN-2 [nTPM]":"13.8","Cell RNA - Daudi [nTPM]":"43.5","Cell RNA - EFO-21 [nTPM]":"11.6","Cell RNA - fHDF\/TERT166 [nTPM]":"25.5","Cell RNA - GAMG [nTPM]":"20.0","Cell RNA - HaCaT [nTPM]":"12.4","Cell RNA - HAP1 [nTPM]":"29.5","Cell RNA - HBEC3-KT [nTPM]":"17.6","Cell RNA - HBF TERT88 [nTPM]":"27.6","Cell RNA - HDLM-2 [nTPM]":"27.5","Cell RNA - HEK 293 [nTPM]":"12.2","Cell RNA - HEL [nTPM]":"47.3","Cell RNA - HeLa [nTPM]":"24.8","Cell RNA - Hep G2 [nTPM]":"12.4","Cell RNA - HHSteC [nTPM]":"11.7","Cell RNA - HL-60 [nTPM]":"34.1","Cell RNA - HMC-1 [nTPM]":"26.5","Cell RNA - HSkMC [nTPM]":"15.2","Cell RNA - hTCEpi [nTPM]":"17.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.7","Cell RNA - hTERT-HME1 [nTPM]":"24.6","Cell RNA - hTERT-RPE1 [nTPM]":"15.3","Cell RNA - HUVEC TERT2 [nTPM]":"20.1","Cell RNA - JURKAT [nTPM]":"22.8","Cell RNA - K-562 [nTPM]":"29.9","Cell RNA - Karpas-707 [nTPM]":"16.6","Cell RNA - LHCN-M2 [nTPM]":"17.8","Cell RNA - MCF7 [nTPM]":"9.5","Cell RNA - MOLT-4 [nTPM]":"26.7","Cell RNA - NB-4 [nTPM]":"8.5","Cell RNA - NTERA-2 [nTPM]":"20.6","Cell RNA - OE19 [nTPM]":"9.4","Cell RNA - PC-3 [nTPM]":"15.4","Cell RNA - REH [nTPM]":"17.5","Cell RNA - RH-30 [nTPM]":"25.6","Cell RNA - RPMI-8226 [nTPM]":"23.2","Cell RNA - RPTEC TERT1 [nTPM]":"12.4","Cell RNA - RT4 [nTPM]":"26.6","Cell RNA - SCLC-21H [nTPM]":"10.9","Cell RNA - SH-SY5Y [nTPM]":"17.6","Cell RNA - SiHa [nTPM]":"29.5","Cell RNA - SK-BR-3 [nTPM]":"11.8","Cell RNA - SK-MEL-30 [nTPM]":"12.0","Cell RNA - SuSa [nTPM]":"17.2","Cell RNA - T-47d [nTPM]":"12.9","Cell RNA - THP-1 [nTPM]":"27.5","Cell RNA - TIME [nTPM]":"26.7","Cell RNA - U-138 MG [nTPM]":"24.6","Cell RNA - U-2 OS [nTPM]":"18.1","Cell RNA - U-2197 [nTPM]":"21.5","Cell RNA - U-251 MG [nTPM]":"29.9","Cell RNA - U-266\/70 [nTPM]":"22.0","Cell RNA - U-266\/84 [nTPM]":"25.4","Cell RNA - U-698 [nTPM]":"43.7","Cell RNA - U-87 MG [nTPM]":"14.2","Cell RNA - U-937 [nTPM]":"19.6","Cell RNA - WM-115 [nTPM]":"14.6","Blood RNA - basophil [nTPM]":"1.3","Blood RNA - classical monocyte [nTPM]":"1.2","Blood RNA - eosinophil [nTPM]":"2.9","Blood RNA - gdT-cell [nTPM]":"2.0","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"1.1","Blood RNA - memory B-cell [nTPM]":"2.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.2","Blood RNA - memory CD8 T-cell [nTPM]":"1.6","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"2.5","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.6","Blood RNA - neutrophil [nTPM]":"3.3","Blood RNA - NK-cell [nTPM]":"3.6","Blood RNA - non-classical monocyte [nTPM]":"1.1","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"8.2","Brain RNA - basal ganglia [nTPM]":"10.5","Brain RNA - cerebellum [nTPM]":"24.1","Brain RNA - cerebral cortex [nTPM]":"8.3","Brain RNA - hippocampal formation [nTPM]":"6.2","Brain RNA - hypothalamus [nTPM]":"6.7","Brain RNA - medulla oblongata [nTPM]":"8.3","Brain RNA - midbrain [nTPM]":"8.5","Brain RNA - pons [nTPM]":"8.4","Brain RNA - spinal cord [nTPM]":"8.1","Brain RNA - thalamus [nTPM]":"7.9","Brain RNA - white matter [nTPM]":"12.8","Single Cell Type RNA - Adipocytes [nTPM]":"50.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"58.8","Single Cell Type RNA - Astrocytes [nTPM]":"115.9","Single Cell Type RNA - B-cells [nTPM]":"58.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"33.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"54.1","Single Cell Type RNA - Bipolar cells [nTPM]":"40.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"31.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"29.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"67.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"53.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.3","Single Cell Type RNA - dendritic cells [nTPM]":"58.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"32.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"20.9","Single Cell Type RNA - Early spermatids [nTPM]":"26.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"62.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"63.0","Single Cell Type RNA - Endothelial cells [nTPM]":"41.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.1","Single Cell Type RNA - Erythroid cells [nTPM]":"38.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"131.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"22.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.7","Single Cell Type RNA - Fibroblasts [nTPM]":"39.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"56.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"66.2","Single Cell Type RNA - granulocytes [nTPM]":"58.8","Single Cell Type RNA - Granulosa cells [nTPM]":"68.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.6","Single Cell Type RNA - Hepatocytes [nTPM]":"29.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.8","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"129.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.2","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"28.8","Single Cell Type RNA - Langerhans cells [nTPM]":"26.5","Single Cell Type RNA - Late spermatids [nTPM]":"35.1","Single Cell Type RNA - Leydig cells [nTPM]":"30.4","Single Cell Type RNA - Macrophages [nTPM]":"42.7","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"148.9","Single Cell Type RNA - monocytes [nTPM]":"37.9","Single Cell Type RNA - Muller glia cells [nTPM]":"22.7","Single Cell Type RNA - NK-cells [nTPM]":"43.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"113.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"143.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"23.7","Single Cell Type RNA - Paneth cells [nTPM]":"22.3","Single Cell Type RNA - Peritubular cells [nTPM]":"33.1","Single Cell Type RNA - Plasma cells [nTPM]":"54.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"31.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"49.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"39.9","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"56.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"42.6","Single Cell Type RNA - Spermatocytes [nTPM]":"71.0","Single Cell Type RNA - Spermatogonia [nTPM]":"29.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"60.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"35.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"18.5","Single Cell Type RNA - T-cells [nTPM]":"65.3","Single Cell Type RNA - Theca cells [nTPM]":"57.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"29.5","Single Cell Type RNA - Urothelial cells [nTPM]":"34.7"},{"Gene":"SETD5","Gene synonym":["FLJ10707"],"Ensembl":"ENSG00000168137","Gene description":"SET domain containing 5","Uniprot":["Q9C0A6"],"Chromosome":"3","Position":"9397615-9479240","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","Methyltransferase","Transferase"],"Disease involvement":["Autism","Autism spectrum disorder","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"263.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017093","HPA035574"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 51: Non-specific - Unknown function","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB017093":null,"HPA035574":"AB_2674681"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.21e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.27e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-3"},"Tissue RNA - adipose tissue [nTPM]":"24.9","Tissue RNA - adrenal gland [nTPM]":"28.1","Tissue RNA - amygdala [nTPM]":"22.3","Tissue RNA - appendix [nTPM]":"19.3","Tissue RNA - basal ganglia [nTPM]":"22.0","Tissue RNA - bone marrow [nTPM]":"14.9","Tissue RNA - breast [nTPM]":"25.4","Tissue RNA - cerebellum [nTPM]":"33.7","Tissue RNA - cerebral cortex [nTPM]":"24.9","Tissue RNA - cervix [nTPM]":"29.5","Tissue RNA - choroid plexus [nTPM]":"20.9","Tissue RNA - colon [nTPM]":"30.5","Tissue RNA - duodenum [nTPM]":"15.2","Tissue RNA - endometrium 1 [nTPM]":"27.6","Tissue RNA - epididymis [nTPM]":"30.2","Tissue RNA - esophagus [nTPM]":"25.0","Tissue RNA - fallopian tube [nTPM]":"30.2","Tissue RNA - gallbladder [nTPM]":"18.8","Tissue RNA - heart muscle [nTPM]":"23.0","Tissue RNA - hippocampal formation [nTPM]":"23.5","Tissue RNA - hypothalamus [nTPM]":"22.3","Tissue RNA - kidney [nTPM]":"18.3","Tissue RNA - liver [nTPM]":"27.6","Tissue RNA - lung [nTPM]":"33.5","Tissue RNA - lymph node [nTPM]":"23.1","Tissue RNA - medulla oblongata [nTPM]":"20.5","Tissue RNA - midbrain [nTPM]":"20.3","Tissue RNA - ovary [nTPM]":"33.2","Tissue RNA - pancreas [nTPM]":"28.5","Tissue RNA - parathyroid gland [nTPM]":"18.0","Tissue RNA - pituitary gland [nTPM]":"26.5","Tissue RNA - placenta [nTPM]":"24.0","Tissue RNA - pons [nTPM]":"21.1","Tissue RNA - prostate [nTPM]":"25.6","Tissue RNA - rectum [nTPM]":"20.9","Tissue RNA - retina [nTPM]":"33.9","Tissue RNA - salivary gland [nTPM]":"28.3","Tissue RNA - seminal vesicle [nTPM]":"20.4","Tissue RNA - skeletal muscle [nTPM]":"23.9","Tissue RNA - skin 1 [nTPM]":"32.8","Tissue RNA - small intestine [nTPM]":"25.6","Tissue RNA - smooth muscle [nTPM]":"23.2","Tissue RNA - spinal cord [nTPM]":"18.6","Tissue RNA - spleen [nTPM]":"26.1","Tissue RNA - stomach 1 [nTPM]":"23.9","Tissue RNA - testis [nTPM]":"17.8","Tissue RNA - thalamus [nTPM]":"22.2","Tissue RNA - thymus [nTPM]":"25.5","Tissue RNA - thyroid gland [nTPM]":"30.5","Tissue RNA - tongue [nTPM]":"21.5","Tissue RNA - tonsil [nTPM]":"26.7","Tissue RNA - urinary bladder [nTPM]":"26.5","Tissue RNA - vagina [nTPM]":"28.1","Tissue RNA - white matter [nTPM]":"24.2","Cell RNA - A-431 [nTPM]":"25.3","Cell RNA - A549 [nTPM]":"28.6","Cell RNA - AF22 [nTPM]":"57.8","Cell RNA - AN3-CA [nTPM]":"27.0","Cell RNA - ASC diff [nTPM]":"36.5","Cell RNA - ASC TERT1 [nTPM]":"33.6","Cell RNA - BEWO [nTPM]":"138.5","Cell RNA - BJ [nTPM]":"24.9","Cell RNA - BJ hTERT+ [nTPM]":"30.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"31.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"35.4","Cell RNA - CACO-2 [nTPM]":"29.1","Cell RNA - CAPAN-2 [nTPM]":"30.2","Cell RNA - Daudi [nTPM]":"53.5","Cell RNA - EFO-21 [nTPM]":"14.3","Cell RNA - fHDF\/TERT166 [nTPM]":"33.4","Cell RNA - GAMG [nTPM]":"29.8","Cell RNA - HaCaT [nTPM]":"20.0","Cell RNA - HAP1 [nTPM]":"50.6","Cell RNA - HBEC3-KT [nTPM]":"29.8","Cell RNA - HBF TERT88 [nTPM]":"35.5","Cell RNA - HDLM-2 [nTPM]":"38.4","Cell RNA - HEK 293 [nTPM]":"27.6","Cell RNA - HEL [nTPM]":"50.6","Cell RNA - HeLa [nTPM]":"56.4","Cell RNA - Hep G2 [nTPM]":"29.8","Cell RNA - HHSteC [nTPM]":"36.7","Cell RNA - HL-60 [nTPM]":"42.0","Cell RNA - HMC-1 [nTPM]":"31.9","Cell RNA - HSkMC [nTPM]":"35.0","Cell RNA - hTCEpi [nTPM]":"52.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"49.3","Cell RNA - hTERT-HME1 [nTPM]":"55.1","Cell RNA - hTERT-RPE1 [nTPM]":"37.3","Cell RNA - HUVEC TERT2 [nTPM]":"35.7","Cell RNA - JURKAT [nTPM]":"35.6","Cell RNA - K-562 [nTPM]":"50.0","Cell RNA - Karpas-707 [nTPM]":"40.0","Cell RNA - LHCN-M2 [nTPM]":"32.6","Cell RNA - MCF7 [nTPM]":"36.4","Cell RNA - MOLT-4 [nTPM]":"35.7","Cell RNA - NB-4 [nTPM]":"38.1","Cell RNA - NTERA-2 [nTPM]":"42.2","Cell RNA - OE19 [nTPM]":"19.5","Cell RNA - PC-3 [nTPM]":"23.9","Cell RNA - REH [nTPM]":"37.7","Cell RNA - RH-30 [nTPM]":"47.6","Cell RNA - RPMI-8226 [nTPM]":"26.2","Cell RNA - RPTEC TERT1 [nTPM]":"29.6","Cell RNA - RT4 [nTPM]":"37.7","Cell RNA - SCLC-21H [nTPM]":"22.3","Cell RNA - SH-SY5Y [nTPM]":"34.6","Cell RNA - SiHa [nTPM]":"34.2","Cell RNA - SK-BR-3 [nTPM]":"29.8","Cell RNA - SK-MEL-30 [nTPM]":"22.6","Cell RNA - SuSa [nTPM]":"52.6","Cell RNA - T-47d [nTPM]":"39.7","Cell RNA - THP-1 [nTPM]":"30.8","Cell RNA - TIME [nTPM]":"41.6","Cell RNA - U-138 MG [nTPM]":"35.3","Cell RNA - U-2 OS [nTPM]":"41.6","Cell RNA - U-2197 [nTPM]":"21.0","Cell RNA - U-251 MG [nTPM]":"28.9","Cell RNA - U-266\/70 [nTPM]":"27.4","Cell RNA - U-266\/84 [nTPM]":"34.2","Cell RNA - U-698 [nTPM]":"83.6","Cell RNA - U-87 MG [nTPM]":"26.9","Cell RNA - U-937 [nTPM]":"30.4","Cell RNA - WM-115 [nTPM]":"33.2","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.9","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"22.3","Brain RNA - basal ganglia [nTPM]":"22.0","Brain RNA - cerebellum [nTPM]":"33.7","Brain RNA - cerebral cortex [nTPM]":"24.9","Brain RNA - hippocampal formation [nTPM]":"23.5","Brain RNA - hypothalamus [nTPM]":"22.3","Brain RNA - medulla oblongata [nTPM]":"20.5","Brain RNA - midbrain [nTPM]":"20.3","Brain RNA - pons [nTPM]":"21.1","Brain RNA - spinal cord [nTPM]":"18.6","Brain RNA - thalamus [nTPM]":"22.2","Brain RNA - white matter [nTPM]":"24.2","Single Cell Type RNA - Adipocytes [nTPM]":"51.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"50.6","Single Cell Type RNA - Astrocytes [nTPM]":"136.1","Single Cell Type RNA - B-cells [nTPM]":"53.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"93.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"54.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"28.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"86.6","Single Cell Type RNA - Bipolar cells [nTPM]":"110.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"45.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"26.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"41.5","Single Cell Type RNA - Club cells [nTPM]":"50.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"42.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"114.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"38.9","Single Cell Type RNA - dendritic cells [nTPM]":"50.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"39.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"37.3","Single Cell Type RNA - Early spermatids [nTPM]":"7.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"45.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"60.3","Single Cell Type RNA - Endothelial cells [nTPM]":"62.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"62.4","Single Cell Type RNA - Erythroid cells [nTPM]":"34.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"175.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"34.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"41.3","Single Cell Type RNA - Fibroblasts [nTPM]":"62.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"45.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"49.4","Single Cell Type RNA - granulocytes [nTPM]":"48.1","Single Cell Type RNA - Granulosa cells [nTPM]":"60.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"63.1","Single Cell Type RNA - Hepatocytes [nTPM]":"50.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.4","Single Cell Type RNA - Horizontal cells [nTPM]":"55.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"188.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"51.9","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"32.4","Single Cell Type RNA - Langerhans cells [nTPM]":"70.7","Single Cell Type RNA - Late spermatids [nTPM]":"11.7","Single Cell Type RNA - Leydig cells [nTPM]":"66.8","Single Cell Type RNA - Macrophages [nTPM]":"30.8","Single Cell Type RNA - Melanocytes [nTPM]":"44.4","Single Cell Type RNA - Microglial cells [nTPM]":"108.7","Single Cell Type RNA - monocytes [nTPM]":"39.7","Single Cell Type RNA - Muller glia cells [nTPM]":"33.4","Single Cell Type RNA - NK-cells [nTPM]":"39.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"263.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"131.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"44.2","Single Cell Type RNA - Paneth cells [nTPM]":"46.2","Single Cell Type RNA - Peritubular cells [nTPM]":"53.8","Single Cell Type RNA - Plasma cells [nTPM]":"67.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"88.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"39.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"52.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"60.9","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"65.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"52.8","Single Cell Type RNA - Spermatocytes [nTPM]":"50.6","Single Cell Type RNA - Spermatogonia [nTPM]":"37.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"75.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"91.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"57.3","Single Cell Type RNA - T-cells [nTPM]":"49.6","Single Cell Type RNA - Theca cells [nTPM]":"56.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"47.8","Single Cell Type RNA - Urothelial cells [nTPM]":"84.2"},{"Gene":"SFXN4","Gene synonym":["SLC56A4"],"Ensembl":"ENSG00000183605","Gene description":"Sideroflexin 4","Uniprot":["Q6P4A7"],"Chromosome":"10","Position":"119140767-119165714","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Transport"],"Molecular function":null,"Disease involvement":["Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018028","HPA020872"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA018028":"AB_1856792","HPA020872":"AB_1856793"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-3"},"Tissue RNA - adipose tissue [nTPM]":"13.3","Tissue RNA - adrenal gland [nTPM]":"35.9","Tissue RNA - amygdala [nTPM]":"9.9","Tissue RNA - appendix [nTPM]":"10.1","Tissue RNA - basal ganglia [nTPM]":"12.5","Tissue RNA - bone marrow [nTPM]":"16.4","Tissue RNA - breast [nTPM]":"14.1","Tissue RNA - cerebellum [nTPM]":"12.8","Tissue RNA - cerebral cortex [nTPM]":"13.6","Tissue RNA - cervix [nTPM]":"14.2","Tissue RNA - choroid plexus [nTPM]":"17.0","Tissue RNA - colon [nTPM]":"21.9","Tissue RNA - duodenum [nTPM]":"20.4","Tissue RNA - endometrium 1 [nTPM]":"11.1","Tissue RNA - epididymis [nTPM]":"13.5","Tissue RNA - esophagus [nTPM]":"19.1","Tissue RNA - fallopian tube [nTPM]":"14.3","Tissue RNA - gallbladder [nTPM]":"8.6","Tissue RNA - heart muscle [nTPM]":"33.1","Tissue RNA - hippocampal formation [nTPM]":"10.2","Tissue RNA - hypothalamus [nTPM]":"12.4","Tissue RNA - kidney [nTPM]":"24.5","Tissue RNA - liver [nTPM]":"36.4","Tissue RNA - lung [nTPM]":"8.5","Tissue RNA - lymph node [nTPM]":"14.4","Tissue RNA - medulla oblongata [nTPM]":"11.3","Tissue RNA - midbrain [nTPM]":"12.5","Tissue RNA - ovary [nTPM]":"16.0","Tissue RNA - pancreas [nTPM]":"33.7","Tissue RNA - parathyroid gland [nTPM]":"23.1","Tissue RNA - pituitary gland [nTPM]":"21.5","Tissue RNA - placenta [nTPM]":"8.8","Tissue RNA - pons [nTPM]":"11.6","Tissue RNA - prostate [nTPM]":"18.8","Tissue RNA - rectum [nTPM]":"22.7","Tissue RNA - retina [nTPM]":"5.7","Tissue RNA - salivary gland [nTPM]":"27.8","Tissue RNA - seminal vesicle [nTPM]":"13.2","Tissue RNA - skeletal muscle [nTPM]":"51.4","Tissue RNA - skin 1 [nTPM]":"11.5","Tissue RNA - small intestine [nTPM]":"17.3","Tissue RNA - smooth muscle [nTPM]":"12.2","Tissue RNA - spinal cord [nTPM]":"10.6","Tissue RNA - spleen [nTPM]":"20.9","Tissue RNA - stomach 1 [nTPM]":"17.3","Tissue RNA - testis [nTPM]":"11.9","Tissue RNA - thalamus [nTPM]":"11.3","Tissue RNA - thymus [nTPM]":"11.0","Tissue RNA - thyroid gland [nTPM]":"24.7","Tissue RNA - tongue [nTPM]":"59.3","Tissue RNA - tonsil [nTPM]":"17.8","Tissue RNA - urinary bladder [nTPM]":"16.4","Tissue RNA - vagina [nTPM]":"13.8","Tissue RNA - white matter [nTPM]":"12.5","Cell RNA - A-431 [nTPM]":"26.2","Cell RNA - A549 [nTPM]":"27.6","Cell RNA - AF22 [nTPM]":"8.7","Cell RNA - AN3-CA [nTPM]":"41.8","Cell RNA - ASC diff [nTPM]":"10.4","Cell RNA - ASC TERT1 [nTPM]":"19.7","Cell RNA - BEWO [nTPM]":"33.0","Cell RNA - BJ [nTPM]":"16.3","Cell RNA - BJ hTERT+ [nTPM]":"19.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.8","Cell RNA - CACO-2 [nTPM]":"45.9","Cell RNA - CAPAN-2 [nTPM]":"43.2","Cell RNA - Daudi [nTPM]":"62.6","Cell RNA - EFO-21 [nTPM]":"15.6","Cell RNA - fHDF\/TERT166 [nTPM]":"14.9","Cell RNA - GAMG [nTPM]":"22.4","Cell RNA - HaCaT [nTPM]":"48.2","Cell RNA - HAP1 [nTPM]":"57.5","Cell RNA - HBEC3-KT [nTPM]":"36.3","Cell RNA - HBF TERT88 [nTPM]":"24.3","Cell RNA - HDLM-2 [nTPM]":"33.1","Cell RNA - HEK 293 [nTPM]":"65.7","Cell RNA - HEL [nTPM]":"28.7","Cell RNA - HeLa [nTPM]":"18.4","Cell RNA - Hep G2 [nTPM]":"47.3","Cell RNA - HHSteC [nTPM]":"37.1","Cell RNA - HL-60 [nTPM]":"49.7","Cell RNA - HMC-1 [nTPM]":"28.8","Cell RNA - HSkMC [nTPM]":"21.1","Cell RNA - hTCEpi [nTPM]":"34.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.0","Cell RNA - hTERT-HME1 [nTPM]":"63.8","Cell RNA - hTERT-RPE1 [nTPM]":"19.5","Cell RNA - HUVEC TERT2 [nTPM]":"25.0","Cell RNA - JURKAT [nTPM]":"46.5","Cell RNA - K-562 [nTPM]":"45.2","Cell RNA - Karpas-707 [nTPM]":"17.5","Cell RNA - LHCN-M2 [nTPM]":"13.6","Cell RNA - MCF7 [nTPM]":"29.6","Cell RNA - MOLT-4 [nTPM]":"53.8","Cell RNA - NB-4 [nTPM]":"60.4","Cell RNA - NTERA-2 [nTPM]":"11.8","Cell RNA - OE19 [nTPM]":"50.2","Cell RNA - PC-3 [nTPM]":"32.5","Cell RNA - REH [nTPM]":"51.7","Cell RNA - RH-30 [nTPM]":"27.1","Cell RNA - RPMI-8226 [nTPM]":"49.0","Cell RNA - RPTEC TERT1 [nTPM]":"24.3","Cell RNA - RT4 [nTPM]":"17.3","Cell RNA - SCLC-21H [nTPM]":"25.2","Cell RNA - SH-SY5Y [nTPM]":"13.9","Cell RNA - SiHa [nTPM]":"10.8","Cell RNA - SK-BR-3 [nTPM]":"42.2","Cell RNA - SK-MEL-30 [nTPM]":"61.9","Cell RNA - SuSa [nTPM]":"11.1","Cell RNA - T-47d [nTPM]":"26.0","Cell RNA - THP-1 [nTPM]":"28.4","Cell RNA - TIME [nTPM]":"11.5","Cell RNA - U-138 MG [nTPM]":"10.6","Cell RNA - U-2 OS [nTPM]":"21.9","Cell RNA - U-2197 [nTPM]":"19.8","Cell RNA - U-251 MG [nTPM]":"37.6","Cell RNA - U-266\/70 [nTPM]":"42.6","Cell RNA - U-266\/84 [nTPM]":"53.0","Cell RNA - U-698 [nTPM]":"56.3","Cell RNA - U-87 MG [nTPM]":"16.2","Cell RNA - U-937 [nTPM]":"72.6","Cell RNA - WM-115 [nTPM]":"7.2","Blood RNA - basophil [nTPM]":"2.5","Blood RNA - classical monocyte [nTPM]":"18.1","Blood RNA - eosinophil [nTPM]":"1.9","Blood RNA - gdT-cell [nTPM]":"6.5","Blood RNA - intermediate monocyte [nTPM]":"19.5","Blood RNA - MAIT T-cell [nTPM]":"10.8","Blood RNA - memory B-cell [nTPM]":"12.5","Blood RNA - memory CD4 T-cell [nTPM]":"7.9","Blood RNA - memory CD8 T-cell [nTPM]":"7.1","Blood RNA - myeloid DC [nTPM]":"21.2","Blood RNA - naive B-cell [nTPM]":"7.0","Blood RNA - naive CD4 T-cell [nTPM]":"12.1","Blood RNA - naive CD8 T-cell [nTPM]":"9.8","Blood RNA - neutrophil [nTPM]":"2.2","Blood RNA - NK-cell [nTPM]":"7.3","Blood RNA - non-classical monocyte [nTPM]":"15.9","Blood RNA - plasmacytoid DC [nTPM]":"10.6","Blood RNA - T-reg [nTPM]":"6.0","Blood RNA - total PBMC [nTPM]":"11.1","Brain RNA - amygdala [nTPM]":"9.9","Brain RNA - basal ganglia [nTPM]":"12.5","Brain RNA - cerebellum [nTPM]":"12.8","Brain RNA - cerebral cortex [nTPM]":"13.6","Brain RNA - hippocampal formation [nTPM]":"10.2","Brain RNA - hypothalamus [nTPM]":"12.4","Brain RNA - medulla oblongata [nTPM]":"11.3","Brain RNA - midbrain [nTPM]":"12.5","Brain RNA - pons [nTPM]":"11.6","Brain RNA - spinal cord [nTPM]":"10.6","Brain RNA - thalamus [nTPM]":"11.3","Brain RNA - white matter [nTPM]":"12.5","Single Cell Type RNA - Adipocytes [nTPM]":"8.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.6","Single Cell Type RNA - Astrocytes [nTPM]":"29.0","Single Cell Type RNA - B-cells [nTPM]":"16.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"25.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"39.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.3","Single Cell Type RNA - Bipolar cells [nTPM]":"7.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"36.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"19.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"37.6","Single Cell Type RNA - dendritic cells [nTPM]":"6.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"58.7","Single Cell Type RNA - Ductal cells [nTPM]":"28.4","Single Cell Type RNA - Early spermatids [nTPM]":"27.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.9","Single Cell Type RNA - Endothelial cells [nTPM]":"8.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.0","Single Cell Type RNA - Erythroid cells [nTPM]":"33.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"25.8","Single Cell Type RNA - Fibroblasts [nTPM]":"12.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.9","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"28.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.1","Single Cell Type RNA - Hepatocytes [nTPM]":"31.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"29.2","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"29.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.7","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"17.6","Single Cell Type RNA - Langerhans cells [nTPM]":"5.0","Single Cell Type RNA - Late spermatids [nTPM]":"69.3","Single Cell Type RNA - Leydig cells [nTPM]":"8.7","Single Cell Type RNA - Macrophages [nTPM]":"13.1","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"11.3","Single Cell Type RNA - Muller glia cells [nTPM]":"7.7","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"22.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.6","Single Cell Type RNA - Paneth cells [nTPM]":"12.1","Single Cell Type RNA - Peritubular cells [nTPM]":"13.5","Single Cell Type RNA - Plasma cells [nTPM]":"31.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"28.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"29.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"65.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.6","Single Cell Type RNA - Spermatocytes [nTPM]":"27.7","Single Cell Type RNA - Spermatogonia [nTPM]":"15.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"21.9","Single Cell Type RNA - T-cells [nTPM]":"9.2","Single Cell Type RNA - Theca cells [nTPM]":"44.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"45.8","Single Cell Type RNA - Urothelial cells [nTPM]":"20.5"},{"Gene":"SGMS2","Gene synonym":["MGC26963","SMS2"],"Ensembl":"ENSG00000164023","Gene description":"Sphingomyelin synthase 2","Uniprot":["Q8NHU3"],"Chromosome":"4","Position":"107824563-107915047","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"126.6","Basal prostatic cells":"167.4","Endometrial ciliated cells":"172.1","Glandular and luminal cells":"147.8","Urothelial cells":"159.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"classical monocyte":"3.7","eosinophil":"2.4","intermediate monocyte":"1.5","myeloid DC":"4.2","non-classical monocyte":"1.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"35","RNA blood lineage specific nTPM":{"dendritic cells":"4.2","granulocytes":"2.4","monocytes":"3.7"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015076"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA015076":"AB_1857298"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.37e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-3"},"Tissue RNA - adipose tissue [nTPM]":"8.6","Tissue RNA - adrenal gland [nTPM]":"3.0","Tissue RNA - amygdala [nTPM]":"5.2","Tissue RNA - appendix [nTPM]":"9.0","Tissue RNA - basal ganglia [nTPM]":"15.3","Tissue RNA - bone marrow [nTPM]":"4.6","Tissue RNA - breast [nTPM]":"5.2","Tissue RNA - cerebellum [nTPM]":"10.1","Tissue RNA - cerebral cortex [nTPM]":"7.8","Tissue RNA - cervix [nTPM]":"12.7","Tissue RNA - choroid plexus [nTPM]":"36.7","Tissue RNA - colon [nTPM]":"12.3","Tissue RNA - duodenum [nTPM]":"19.5","Tissue RNA - endometrium 1 [nTPM]":"8.8","Tissue RNA - epididymis [nTPM]":"4.6","Tissue RNA - esophagus [nTPM]":"16.4","Tissue RNA - fallopian tube [nTPM]":"12.5","Tissue RNA - gallbladder [nTPM]":"39.6","Tissue RNA - heart muscle [nTPM]":"9.1","Tissue RNA - hippocampal formation [nTPM]":"3.3","Tissue RNA - hypothalamus [nTPM]":"6.5","Tissue RNA - kidney [nTPM]":"14.5","Tissue RNA - liver [nTPM]":"20.4","Tissue RNA - lung [nTPM]":"27.8","Tissue RNA - lymph node [nTPM]":"1.1","Tissue RNA - medulla oblongata [nTPM]":"13.9","Tissue RNA - midbrain [nTPM]":"14.3","Tissue RNA - ovary [nTPM]":"1.1","Tissue RNA - pancreas [nTPM]":"11.7","Tissue RNA - parathyroid gland [nTPM]":"3.6","Tissue RNA - pituitary gland [nTPM]":"4.7","Tissue RNA - placenta [nTPM]":"5.1","Tissue RNA - pons [nTPM]":"13.0","Tissue RNA - prostate [nTPM]":"9.6","Tissue RNA - rectum [nTPM]":"10.6","Tissue RNA - retina [nTPM]":"0.8","Tissue RNA - salivary gland [nTPM]":"9.2","Tissue RNA - seminal vesicle [nTPM]":"4.6","Tissue RNA - skeletal muscle [nTPM]":"2.5","Tissue RNA - skin 1 [nTPM]":"3.6","Tissue RNA - small intestine [nTPM]":"16.5","Tissue RNA - smooth muscle [nTPM]":"29.1","Tissue RNA - spinal cord [nTPM]":"10.2","Tissue RNA - spleen [nTPM]":"1.1","Tissue RNA - stomach 1 [nTPM]":"13.8","Tissue RNA - testis [nTPM]":"9.6","Tissue RNA - thalamus [nTPM]":"10.6","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"18.0","Tissue RNA - tongue [nTPM]":"3.4","Tissue RNA - tonsil [nTPM]":"2.9","Tissue RNA - urinary bladder [nTPM]":"13.9","Tissue RNA - vagina [nTPM]":"4.2","Tissue RNA - white matter [nTPM]":"21.6","Cell RNA - A-431 [nTPM]":"20.8","Cell RNA - A549 [nTPM]":"7.7","Cell RNA - AF22 [nTPM]":"1.1","Cell RNA - AN3-CA [nTPM]":"5.8","Cell RNA - ASC diff [nTPM]":"12.9","Cell RNA - ASC TERT1 [nTPM]":"29.9","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"25.0","Cell RNA - BJ hTERT+ [nTPM]":"18.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.1","Cell RNA - CACO-2 [nTPM]":"3.5","Cell RNA - CAPAN-2 [nTPM]":"42.1","Cell RNA - Daudi [nTPM]":"1.5","Cell RNA - EFO-21 [nTPM]":"9.7","Cell RNA - fHDF\/TERT166 [nTPM]":"40.0","Cell RNA - GAMG [nTPM]":"10.1","Cell RNA - HaCaT [nTPM]":"7.6","Cell RNA - HAP1 [nTPM]":"14.5","Cell RNA - HBEC3-KT [nTPM]":"22.1","Cell RNA - HBF TERT88 [nTPM]":"20.7","Cell RNA - HDLM-2 [nTPM]":"5.9","Cell RNA - HEK 293 [nTPM]":"5.7","Cell RNA - HEL [nTPM]":"0.9","Cell RNA - HeLa [nTPM]":"16.5","Cell RNA - Hep G2 [nTPM]":"1.2","Cell RNA - HHSteC [nTPM]":"14.8","Cell RNA - HL-60 [nTPM]":"14.2","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"10.4","Cell RNA - hTCEpi [nTPM]":"15.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.7","Cell RNA - hTERT-HME1 [nTPM]":"27.4","Cell RNA - hTERT-RPE1 [nTPM]":"24.2","Cell RNA - HUVEC TERT2 [nTPM]":"26.1","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"18.6","Cell RNA - MCF7 [nTPM]":"6.9","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.7","Cell RNA - OE19 [nTPM]":"12.1","Cell RNA - PC-3 [nTPM]":"8.6","Cell RNA - REH [nTPM]":"0.5","Cell RNA - RH-30 [nTPM]":"9.9","Cell RNA - RPMI-8226 [nTPM]":"2.9","Cell RNA - RPTEC TERT1 [nTPM]":"30.7","Cell RNA - RT4 [nTPM]":"10.0","Cell RNA - SCLC-21H [nTPM]":"2.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"19.1","Cell RNA - SK-BR-3 [nTPM]":"26.9","Cell RNA - SK-MEL-30 [nTPM]":"3.3","Cell RNA - SuSa [nTPM]":"3.0","Cell RNA - T-47d [nTPM]":"14.5","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"44.7","Cell RNA - U-138 MG [nTPM]":"13.9","Cell RNA - U-2 OS [nTPM]":"21.9","Cell RNA - U-2197 [nTPM]":"20.1","Cell RNA - U-251 MG [nTPM]":"11.7","Cell RNA - U-266\/70 [nTPM]":"1.4","Cell RNA - U-266\/84 [nTPM]":"0.5","Cell RNA - U-698 [nTPM]":"0.8","Cell RNA - U-87 MG [nTPM]":"18.7","Cell RNA - U-937 [nTPM]":"3.4","Cell RNA - WM-115 [nTPM]":"5.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"3.7","Blood RNA - eosinophil [nTPM]":"2.4","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"4.2","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"5.2","Brain RNA - basal ganglia [nTPM]":"15.3","Brain RNA - cerebellum [nTPM]":"10.1","Brain RNA - cerebral cortex [nTPM]":"7.8","Brain RNA - hippocampal formation [nTPM]":"3.3","Brain RNA - hypothalamus [nTPM]":"6.5","Brain RNA - medulla oblongata [nTPM]":"13.9","Brain RNA - midbrain [nTPM]":"14.3","Brain RNA - pons [nTPM]":"13.0","Brain RNA - spinal cord [nTPM]":"10.2","Brain RNA - thalamus [nTPM]":"10.6","Brain RNA - white matter [nTPM]":"21.6","Single Cell Type RNA - Adipocytes [nTPM]":"3.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"86.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"126.6","Single Cell Type RNA - Astrocytes [nTPM]":"7.2","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"56.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"167.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"20.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"28.6","Single Cell Type RNA - Club cells [nTPM]":"88.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - dendritic cells [nTPM]":"2.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"32.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"19.8","Single Cell Type RNA - Early spermatids [nTPM]":"71.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"172.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.5","Single Cell Type RNA - Endothelial cells [nTPM]":"10.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.9","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.9","Single Cell Type RNA - Fibroblasts [nTPM]":"26.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"58.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"147.8","Single Cell Type RNA - granulocytes [nTPM]":"10.1","Single Cell Type RNA - Granulosa cells [nTPM]":"2.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.4","Single Cell Type RNA - Hepatocytes [nTPM]":"25.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.5","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.0","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"22.1","Single Cell Type RNA - Langerhans cells [nTPM]":"43.0","Single Cell Type RNA - Late spermatids [nTPM]":"11.1","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"28.2","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"23.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"37.9","Single Cell Type RNA - Paneth cells [nTPM]":"60.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"96.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"33.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"104.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"46.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.9","Single Cell Type RNA - Spermatogonia [nTPM]":"3.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"38.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"72.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"13.8","Single Cell Type RNA - T-cells [nTPM]":"3.3","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"21.8","Single Cell Type RNA - Urothelial cells [nTPM]":"159.7"},{"Gene":"SGPL1","Gene synonym":["SPL"],"Ensembl":"ENSG00000166224","Gene description":"Sphingosine-1-phosphate lyase 1","Uniprot":["O95470"],"Chromosome":"10","Position":"70815948-70881184","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Lyase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RT4":"112.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021125","HPA023086"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA021125":"AB_1856803","HPA023086":"AB_1856804"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.52e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-3"},"Tissue RNA - adipose tissue [nTPM]":"12.0","Tissue RNA - adrenal gland [nTPM]":"12.7","Tissue RNA - amygdala [nTPM]":"15.8","Tissue RNA - appendix [nTPM]":"18.0","Tissue RNA - basal ganglia [nTPM]":"17.4","Tissue RNA - bone marrow [nTPM]":"6.8","Tissue RNA - breast [nTPM]":"13.0","Tissue RNA - cerebellum [nTPM]":"15.2","Tissue RNA - cerebral cortex [nTPM]":"16.3","Tissue RNA - cervix [nTPM]":"17.6","Tissue RNA - choroid plexus [nTPM]":"11.0","Tissue RNA - colon [nTPM]":"16.7","Tissue RNA - duodenum [nTPM]":"16.0","Tissue RNA - endometrium 1 [nTPM]":"14.4","Tissue RNA - epididymis [nTPM]":"18.8","Tissue RNA - esophagus [nTPM]":"27.9","Tissue RNA - fallopian tube [nTPM]":"15.3","Tissue RNA - gallbladder [nTPM]":"12.6","Tissue RNA - heart muscle [nTPM]":"6.4","Tissue RNA - hippocampal formation [nTPM]":"14.7","Tissue RNA - hypothalamus [nTPM]":"16.4","Tissue RNA - kidney [nTPM]":"15.5","Tissue RNA - liver [nTPM]":"22.9","Tissue RNA - lung [nTPM]":"10.7","Tissue RNA - lymph node [nTPM]":"18.1","Tissue RNA - medulla oblongata [nTPM]":"18.6","Tissue RNA - midbrain [nTPM]":"16.7","Tissue RNA - ovary [nTPM]":"9.0","Tissue RNA - pancreas [nTPM]":"18.5","Tissue RNA - parathyroid gland [nTPM]":"21.0","Tissue RNA - pituitary gland [nTPM]":"9.4","Tissue RNA - placenta [nTPM]":"10.0","Tissue RNA - pons [nTPM]":"17.4","Tissue RNA - prostate [nTPM]":"17.5","Tissue RNA - rectum [nTPM]":"17.9","Tissue RNA - retina [nTPM]":"10.8","Tissue RNA - salivary gland [nTPM]":"14.3","Tissue RNA - seminal vesicle [nTPM]":"12.4","Tissue RNA - skeletal muscle [nTPM]":"9.6","Tissue RNA - skin 1 [nTPM]":"30.4","Tissue RNA - small intestine [nTPM]":"22.8","Tissue RNA - smooth muscle [nTPM]":"13.9","Tissue RNA - spinal cord [nTPM]":"17.4","Tissue RNA - spleen [nTPM]":"16.1","Tissue RNA - stomach 1 [nTPM]":"12.3","Tissue RNA - testis [nTPM]":"14.0","Tissue RNA - thalamus [nTPM]":"17.7","Tissue RNA - thymus [nTPM]":"17.9","Tissue RNA - thyroid gland [nTPM]":"20.1","Tissue RNA - tongue [nTPM]":"6.0","Tissue RNA - tonsil [nTPM]":"20.1","Tissue RNA - urinary bladder [nTPM]":"25.0","Tissue RNA - vagina [nTPM]":"14.7","Tissue RNA - white matter [nTPM]":"19.8","Cell RNA - A-431 [nTPM]":"26.9","Cell RNA - A549 [nTPM]":"35.2","Cell RNA - AF22 [nTPM]":"33.2","Cell RNA - AN3-CA [nTPM]":"38.1","Cell RNA - ASC diff [nTPM]":"8.9","Cell RNA - ASC TERT1 [nTPM]":"11.5","Cell RNA - BEWO [nTPM]":"22.1","Cell RNA - BJ [nTPM]":"15.5","Cell RNA - BJ hTERT+ [nTPM]":"16.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.4","Cell RNA - CACO-2 [nTPM]":"38.4","Cell RNA - CAPAN-2 [nTPM]":"57.8","Cell RNA - Daudi [nTPM]":"24.2","Cell RNA - EFO-21 [nTPM]":"18.0","Cell RNA - fHDF\/TERT166 [nTPM]":"15.8","Cell RNA - GAMG [nTPM]":"15.9","Cell RNA - HaCaT [nTPM]":"44.1","Cell RNA - HAP1 [nTPM]":"28.8","Cell RNA - HBEC3-KT [nTPM]":"31.0","Cell RNA - HBF TERT88 [nTPM]":"23.5","Cell RNA - HDLM-2 [nTPM]":"39.1","Cell RNA - HEK 293 [nTPM]":"15.6","Cell RNA - HEL [nTPM]":"2.5","Cell RNA - HeLa [nTPM]":"17.5","Cell RNA - Hep G2 [nTPM]":"46.2","Cell RNA - HHSteC [nTPM]":"33.6","Cell RNA - HL-60 [nTPM]":"10.6","Cell RNA - HMC-1 [nTPM]":"20.9","Cell RNA - HSkMC [nTPM]":"21.8","Cell RNA - hTCEpi [nTPM]":"51.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.1","Cell RNA - hTERT-HME1 [nTPM]":"57.6","Cell RNA - hTERT-RPE1 [nTPM]":"34.6","Cell RNA - HUVEC TERT2 [nTPM]":"10.4","Cell RNA - JURKAT [nTPM]":"22.3","Cell RNA - K-562 [nTPM]":"7.2","Cell RNA - Karpas-707 [nTPM]":"20.4","Cell RNA - LHCN-M2 [nTPM]":"23.6","Cell RNA - MCF7 [nTPM]":"29.6","Cell RNA - MOLT-4 [nTPM]":"13.2","Cell RNA - NB-4 [nTPM]":"7.1","Cell RNA - NTERA-2 [nTPM]":"15.0","Cell RNA - OE19 [nTPM]":"35.4","Cell RNA - PC-3 [nTPM]":"19.5","Cell RNA - REH [nTPM]":"16.6","Cell RNA - RH-30 [nTPM]":"25.2","Cell RNA - RPMI-8226 [nTPM]":"9.1","Cell RNA - RPTEC TERT1 [nTPM]":"26.3","Cell RNA - RT4 [nTPM]":"112.1","Cell RNA - SCLC-21H [nTPM]":"22.6","Cell RNA - SH-SY5Y [nTPM]":"27.5","Cell RNA - SiHa [nTPM]":"30.9","Cell RNA - SK-BR-3 [nTPM]":"46.6","Cell RNA - SK-MEL-30 [nTPM]":"28.5","Cell RNA - SuSa [nTPM]":"25.9","Cell RNA - T-47d [nTPM]":"24.3","Cell RNA - THP-1 [nTPM]":"7.5","Cell RNA - TIME [nTPM]":"20.3","Cell RNA - U-138 MG [nTPM]":"14.8","Cell RNA - U-2 OS [nTPM]":"38.7","Cell RNA - U-2197 [nTPM]":"11.6","Cell RNA - U-251 MG [nTPM]":"30.1","Cell RNA - U-266\/70 [nTPM]":"8.4","Cell RNA - U-266\/84 [nTPM]":"12.6","Cell RNA - U-698 [nTPM]":"11.0","Cell RNA - U-87 MG [nTPM]":"14.7","Cell RNA - U-937 [nTPM]":"19.3","Cell RNA - WM-115 [nTPM]":"10.7","Blood RNA - basophil [nTPM]":"1.1","Blood RNA - classical monocyte [nTPM]":"18.2","Blood RNA - eosinophil [nTPM]":"14.0","Blood RNA - gdT-cell [nTPM]":"18.0","Blood RNA - intermediate monocyte [nTPM]":"34.6","Blood RNA - MAIT T-cell [nTPM]":"16.5","Blood RNA - memory B-cell [nTPM]":"7.2","Blood RNA - memory CD4 T-cell [nTPM]":"11.5","Blood RNA - memory CD8 T-cell [nTPM]":"14.7","Blood RNA - myeloid DC [nTPM]":"16.2","Blood RNA - naive B-cell [nTPM]":"8.7","Blood RNA - naive CD4 T-cell [nTPM]":"8.5","Blood RNA - naive CD8 T-cell [nTPM]":"13.5","Blood RNA - neutrophil [nTPM]":"15.0","Blood RNA - NK-cell [nTPM]":"18.8","Blood RNA - non-classical monocyte [nTPM]":"44.9","Blood RNA - plasmacytoid DC [nTPM]":"8.9","Blood RNA - T-reg [nTPM]":"11.8","Blood RNA - total PBMC [nTPM]":"12.4","Brain RNA - amygdala [nTPM]":"15.8","Brain RNA - basal ganglia [nTPM]":"17.4","Brain RNA - cerebellum [nTPM]":"15.2","Brain RNA - cerebral cortex [nTPM]":"16.3","Brain RNA - hippocampal formation [nTPM]":"14.7","Brain RNA - hypothalamus [nTPM]":"16.4","Brain RNA - medulla oblongata [nTPM]":"18.6","Brain RNA - midbrain [nTPM]":"16.7","Brain RNA - pons [nTPM]":"17.4","Brain RNA - spinal cord [nTPM]":"17.4","Brain RNA - thalamus [nTPM]":"17.7","Brain RNA - white matter [nTPM]":"19.8","Single Cell Type RNA - Adipocytes [nTPM]":"3.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.4","Single Cell Type RNA - Astrocytes [nTPM]":"32.3","Single Cell Type RNA - B-cells [nTPM]":"11.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"6.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"23.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"46.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.3","Single Cell Type RNA - dendritic cells [nTPM]":"16.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"41.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"36.2","Single Cell Type RNA - Early spermatids [nTPM]":"2.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"30.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.3","Single Cell Type RNA - Endothelial cells [nTPM]":"7.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"25.1","Single Cell Type RNA - Erythroid cells [nTPM]":"4.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"48.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"37.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.8","Single Cell Type RNA - Fibroblasts [nTPM]":"10.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"46.1","Single Cell Type RNA - granulocytes [nTPM]":"14.7","Single Cell Type RNA - Granulosa cells [nTPM]":"23.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.1","Single Cell Type RNA - Hepatocytes [nTPM]":"44.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"27.6","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"38.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.2","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"43.1","Single Cell Type RNA - Langerhans cells [nTPM]":"16.1","Single Cell Type RNA - Late spermatids [nTPM]":"5.2","Single Cell Type RNA - Leydig cells [nTPM]":"11.5","Single Cell Type RNA - Macrophages [nTPM]":"25.7","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"35.6","Single Cell Type RNA - monocytes [nTPM]":"22.7","Single Cell Type RNA - Muller glia cells [nTPM]":"9.8","Single Cell Type RNA - NK-cells [nTPM]":"25.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"41.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"43.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"55.6","Single Cell Type RNA - Paneth cells [nTPM]":"18.8","Single Cell Type RNA - Peritubular cells [nTPM]":"20.3","Single Cell Type RNA - Plasma cells [nTPM]":"5.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"26.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"53.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"26.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.0","Single Cell Type RNA - Spermatocytes [nTPM]":"20.0","Single Cell Type RNA - Spermatogonia [nTPM]":"34.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.3","Single Cell Type RNA - T-cells [nTPM]":"11.1","Single Cell Type RNA - Theca cells [nTPM]":"18.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.9","Single Cell Type RNA - Urothelial cells [nTPM]":"25.3"},{"Gene":"SGSH","Gene synonym":["HSS","MPS3A","SFMD"],"Ensembl":"ENSG00000181523","Gene description":"N-sulfoglucosamine sulfohydrolase","Uniprot":["P51688"],"Chromosome":"17","Position":"80206716-80220923","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Mucopolysaccharidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Theca cells":"32.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HHSteC":"62.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023436","HPA023451"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA023436":"AB_1856806","HPA023451":"AB_1856807"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.71e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.72e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.10e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.66e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.37e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Tissue RNA - adipose tissue [nTPM]":"16.6","Tissue RNA - adrenal gland [nTPM]":"45.9","Tissue RNA - amygdala [nTPM]":"1.7","Tissue RNA - appendix [nTPM]":"12.2","Tissue RNA - basal ganglia [nTPM]":"2.3","Tissue RNA - bone marrow [nTPM]":"3.6","Tissue RNA - breast [nTPM]":"17.2","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"5.2","Tissue RNA - cervix [nTPM]":"13.5","Tissue RNA - choroid plexus [nTPM]":"8.8","Tissue RNA - colon [nTPM]":"14.8","Tissue RNA - duodenum [nTPM]":"12.7","Tissue RNA - endometrium 1 [nTPM]":"17.2","Tissue RNA - epididymis [nTPM]":"4.6","Tissue RNA - esophagus [nTPM]":"11.0","Tissue RNA - fallopian tube [nTPM]":"16.0","Tissue RNA - gallbladder [nTPM]":"10.6","Tissue RNA - heart muscle [nTPM]":"9.9","Tissue RNA - hippocampal formation [nTPM]":"2.0","Tissue RNA - hypothalamus [nTPM]":"5.4","Tissue RNA - kidney [nTPM]":"15.7","Tissue RNA - liver [nTPM]":"9.5","Tissue RNA - lung [nTPM]":"18.1","Tissue RNA - lymph node [nTPM]":"13.4","Tissue RNA - medulla oblongata [nTPM]":"4.4","Tissue RNA - midbrain [nTPM]":"7.6","Tissue RNA - ovary [nTPM]":"12.3","Tissue RNA - pancreas [nTPM]":"20.4","Tissue RNA - parathyroid gland [nTPM]":"16.0","Tissue RNA - pituitary gland [nTPM]":"17.0","Tissue RNA - placenta [nTPM]":"12.4","Tissue RNA - pons [nTPM]":"4.2","Tissue RNA - prostate [nTPM]":"19.7","Tissue RNA - rectum [nTPM]":"6.5","Tissue RNA - retina [nTPM]":"2.8","Tissue RNA - salivary gland [nTPM]":"21.8","Tissue RNA - seminal vesicle [nTPM]":"11.1","Tissue RNA - skeletal muscle [nTPM]":"7.0","Tissue RNA - skin 1 [nTPM]":"18.9","Tissue RNA - small intestine [nTPM]":"16.7","Tissue RNA - smooth muscle [nTPM]":"10.6","Tissue RNA - spinal cord [nTPM]":"2.5","Tissue RNA - spleen [nTPM]":"28.4","Tissue RNA - stomach 1 [nTPM]":"17.8","Tissue RNA - testis [nTPM]":"3.9","Tissue RNA - thalamus [nTPM]":"5.3","Tissue RNA - thymus [nTPM]":"4.2","Tissue RNA - thyroid gland [nTPM]":"21.2","Tissue RNA - tongue [nTPM]":"4.6","Tissue RNA - tonsil [nTPM]":"6.9","Tissue RNA - urinary bladder [nTPM]":"15.5","Tissue RNA - vagina [nTPM]":"11.5","Tissue RNA - white matter [nTPM]":"1.8","Cell RNA - A-431 [nTPM]":"2.6","Cell RNA - A549 [nTPM]":"7.9","Cell RNA - AF22 [nTPM]":"9.8","Cell RNA - AN3-CA [nTPM]":"15.6","Cell RNA - ASC diff [nTPM]":"22.5","Cell RNA - ASC TERT1 [nTPM]":"20.2","Cell RNA - BEWO [nTPM]":"10.4","Cell RNA - BJ [nTPM]":"16.0","Cell RNA - BJ hTERT+ [nTPM]":"40.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"27.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.2","Cell RNA - CACO-2 [nTPM]":"9.0","Cell RNA - CAPAN-2 [nTPM]":"9.5","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"25.7","Cell RNA - fHDF\/TERT166 [nTPM]":"24.9","Cell RNA - GAMG [nTPM]":"13.2","Cell RNA - HaCaT [nTPM]":"9.9","Cell RNA - HAP1 [nTPM]":"6.2","Cell RNA - HBEC3-KT [nTPM]":"11.7","Cell RNA - HBF TERT88 [nTPM]":"4.7","Cell RNA - HDLM-2 [nTPM]":"5.3","Cell RNA - HEK 293 [nTPM]":"9.6","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"22.3","Cell RNA - Hep G2 [nTPM]":"25.0","Cell RNA - HHSteC [nTPM]":"62.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"5.9","Cell RNA - HSkMC [nTPM]":"33.9","Cell RNA - hTCEpi [nTPM]":"12.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.9","Cell RNA - hTERT-HME1 [nTPM]":"10.5","Cell RNA - hTERT-RPE1 [nTPM]":"5.8","Cell RNA - HUVEC TERT2 [nTPM]":"50.7","Cell RNA - JURKAT [nTPM]":"4.7","Cell RNA - K-562 [nTPM]":"7.1","Cell RNA - Karpas-707 [nTPM]":"26.2","Cell RNA - LHCN-M2 [nTPM]":"17.9","Cell RNA - MCF7 [nTPM]":"16.2","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"3.3","Cell RNA - OE19 [nTPM]":"10.0","Cell RNA - PC-3 [nTPM]":"13.2","Cell RNA - REH [nTPM]":"1.4","Cell RNA - RH-30 [nTPM]":"3.7","Cell RNA - RPMI-8226 [nTPM]":"21.1","Cell RNA - RPTEC TERT1 [nTPM]":"20.2","Cell RNA - RT4 [nTPM]":"18.5","Cell RNA - SCLC-21H [nTPM]":"2.0","Cell RNA - SH-SY5Y [nTPM]":"11.7","Cell RNA - SiHa [nTPM]":"18.4","Cell RNA - SK-BR-3 [nTPM]":"44.1","Cell RNA - SK-MEL-30 [nTPM]":"10.6","Cell RNA - SuSa [nTPM]":"4.9","Cell RNA - T-47d [nTPM]":"32.8","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"32.5","Cell RNA - U-138 MG [nTPM]":"31.9","Cell RNA - U-2 OS [nTPM]":"7.0","Cell RNA - U-2197 [nTPM]":"11.4","Cell RNA - U-251 MG [nTPM]":"7.4","Cell RNA - U-266\/70 [nTPM]":"26.1","Cell RNA - U-266\/84 [nTPM]":"3.6","Cell RNA - U-698 [nTPM]":"3.9","Cell RNA - U-87 MG [nTPM]":"13.6","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"16.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"20.6","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"12.1","Blood RNA - intermediate monocyte [nTPM]":"8.0","Blood RNA - MAIT T-cell [nTPM]":"16.0","Blood RNA - memory B-cell [nTPM]":"3.5","Blood RNA - memory CD4 T-cell [nTPM]":"10.5","Blood RNA - memory CD8 T-cell [nTPM]":"11.3","Blood RNA - myeloid DC [nTPM]":"20.4","Blood RNA - naive B-cell [nTPM]":"3.8","Blood RNA - naive CD4 T-cell [nTPM]":"8.2","Blood RNA - naive CD8 T-cell [nTPM]":"6.7","Blood RNA - neutrophil [nTPM]":"2.1","Blood RNA - NK-cell [nTPM]":"9.3","Blood RNA - non-classical monocyte [nTPM]":"8.0","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"13.5","Blood RNA - total PBMC [nTPM]":"12.7","Brain RNA - amygdala [nTPM]":"1.7","Brain RNA - basal ganglia [nTPM]":"2.3","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"5.2","Brain RNA - hippocampal formation [nTPM]":"2.0","Brain RNA - hypothalamus [nTPM]":"5.4","Brain RNA - medulla oblongata [nTPM]":"4.4","Brain RNA - midbrain [nTPM]":"7.6","Brain RNA - pons [nTPM]":"4.2","Brain RNA - spinal cord [nTPM]":"2.5","Brain RNA - thalamus [nTPM]":"5.3","Brain RNA - white matter [nTPM]":"1.8","Single Cell Type RNA - Adipocytes [nTPM]":"7.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.8","Single Cell Type RNA - Astrocytes [nTPM]":"4.2","Single Cell Type RNA - B-cells [nTPM]":"5.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"3.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"7.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.2","Single Cell Type RNA - dendritic cells [nTPM]":"5.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"8.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.2","Single Cell Type RNA - Endothelial cells [nTPM]":"10.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.7","Single Cell Type RNA - Fibroblasts [nTPM]":"10.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"13.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.7","Single Cell Type RNA - Hepatocytes [nTPM]":"4.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.3","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"18.2","Single Cell Type RNA - Langerhans cells [nTPM]":"7.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"11.5","Single Cell Type RNA - Macrophages [nTPM]":"13.0","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"8.4","Single Cell Type RNA - Muller glia cells [nTPM]":"4.1","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.8","Single Cell Type RNA - Paneth cells [nTPM]":"6.0","Single Cell Type RNA - Peritubular cells [nTPM]":"14.3","Single Cell Type RNA - Plasma cells [nTPM]":"5.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.9","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"27.0","Single Cell Type RNA - T-cells [nTPM]":"7.2","Single Cell Type RNA - Theca cells [nTPM]":"32.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.0","Single Cell Type RNA - Urothelial cells [nTPM]":"2.9"},{"Gene":"SHPK","Gene synonym":["CARKL","SHK"],"Ensembl":"ENSG00000197417","Gene description":"Sedoheptulokinase","Uniprot":["Q9UHJ6"],"Chromosome":"17","Position":"3608240-3636250","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"19.1","Proximal enterocytes":"18.9","Rod photoreceptor cells":"18.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024361","HPA064939"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"350000","Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Nucleoplasm","Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA024361":"AB_1846030","HPA064939":"AB_2685388"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.4","Tissue RNA - adrenal gland [nTPM]":"9.9","Tissue RNA - amygdala [nTPM]":"3.5","Tissue RNA - appendix [nTPM]":"3.9","Tissue RNA - basal ganglia [nTPM]":"5.0","Tissue RNA - bone marrow [nTPM]":"4.8","Tissue RNA - breast [nTPM]":"6.9","Tissue RNA - cerebellum [nTPM]":"4.1","Tissue RNA - cerebral cortex [nTPM]":"4.4","Tissue RNA - cervix [nTPM]":"9.8","Tissue RNA - choroid plexus [nTPM]":"3.1","Tissue RNA - colon [nTPM]":"6.4","Tissue RNA - duodenum [nTPM]":"13.5","Tissue RNA - endometrium 1 [nTPM]":"4.8","Tissue RNA - epididymis [nTPM]":"2.9","Tissue RNA - esophagus [nTPM]":"9.4","Tissue RNA - fallopian tube [nTPM]":"6.2","Tissue RNA - gallbladder [nTPM]":"3.6","Tissue RNA - heart muscle [nTPM]":"4.5","Tissue RNA - hippocampal formation [nTPM]":"3.4","Tissue RNA - hypothalamus [nTPM]":"3.5","Tissue RNA - kidney [nTPM]":"10.2","Tissue RNA - liver [nTPM]":"23.3","Tissue RNA - lung [nTPM]":"4.7","Tissue RNA - lymph node [nTPM]":"3.9","Tissue RNA - medulla oblongata [nTPM]":"3.9","Tissue RNA - midbrain [nTPM]":"4.8","Tissue RNA - ovary [nTPM]":"7.5","Tissue RNA - pancreas [nTPM]":"10.9","Tissue RNA - parathyroid gland [nTPM]":"8.6","Tissue RNA - pituitary gland [nTPM]":"4.5","Tissue RNA - placenta [nTPM]":"6.2","Tissue RNA - pons [nTPM]":"4.2","Tissue RNA - prostate [nTPM]":"5.7","Tissue RNA - rectum [nTPM]":"6.0","Tissue RNA - retina [nTPM]":"7.1","Tissue RNA - salivary gland [nTPM]":"7.0","Tissue RNA - seminal vesicle [nTPM]":"5.4","Tissue RNA - skeletal muscle [nTPM]":"3.3","Tissue RNA - skin 1 [nTPM]":"9.7","Tissue RNA - small intestine [nTPM]":"11.5","Tissue RNA - smooth muscle [nTPM]":"3.5","Tissue RNA - spinal cord [nTPM]":"3.0","Tissue RNA - spleen [nTPM]":"4.4","Tissue RNA - stomach 1 [nTPM]":"8.4","Tissue RNA - testis [nTPM]":"4.2","Tissue RNA - thalamus [nTPM]":"4.3","Tissue RNA - thymus [nTPM]":"4.5","Tissue RNA - thyroid gland [nTPM]":"5.5","Tissue RNA - tongue [nTPM]":"3.3","Tissue RNA - tonsil [nTPM]":"5.3","Tissue RNA - urinary bladder [nTPM]":"5.6","Tissue RNA - vagina [nTPM]":"7.8","Tissue RNA - white matter [nTPM]":"8.7","Cell RNA - A-431 [nTPM]":"6.7","Cell RNA - A549 [nTPM]":"13.5","Cell RNA - AF22 [nTPM]":"14.0","Cell RNA - AN3-CA [nTPM]":"9.1","Cell RNA - ASC diff [nTPM]":"5.7","Cell RNA - ASC TERT1 [nTPM]":"5.7","Cell RNA - BEWO [nTPM]":"7.8","Cell RNA - BJ [nTPM]":"4.4","Cell RNA - BJ hTERT+ [nTPM]":"4.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.0","Cell RNA - CACO-2 [nTPM]":"23.3","Cell RNA - CAPAN-2 [nTPM]":"6.2","Cell RNA - Daudi [nTPM]":"7.9","Cell RNA - EFO-21 [nTPM]":"9.5","Cell RNA - fHDF\/TERT166 [nTPM]":"8.6","Cell RNA - GAMG [nTPM]":"7.9","Cell RNA - HaCaT [nTPM]":"12.8","Cell RNA - HAP1 [nTPM]":"18.8","Cell RNA - HBEC3-KT [nTPM]":"14.3","Cell RNA - HBF TERT88 [nTPM]":"6.1","Cell RNA - HDLM-2 [nTPM]":"12.8","Cell RNA - HEK 293 [nTPM]":"18.3","Cell RNA - HEL [nTPM]":"8.6","Cell RNA - HeLa [nTPM]":"11.6","Cell RNA - Hep G2 [nTPM]":"17.0","Cell RNA - HHSteC [nTPM]":"6.9","Cell RNA - HL-60 [nTPM]":"7.6","Cell RNA - HMC-1 [nTPM]":"11.8","Cell RNA - HSkMC [nTPM]":"9.7","Cell RNA - hTCEpi [nTPM]":"6.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.4","Cell RNA - hTERT-HME1 [nTPM]":"6.3","Cell RNA - hTERT-RPE1 [nTPM]":"7.2","Cell RNA - HUVEC TERT2 [nTPM]":"16.1","Cell RNA - JURKAT [nTPM]":"6.2","Cell RNA - K-562 [nTPM]":"11.6","Cell RNA - Karpas-707 [nTPM]":"9.8","Cell RNA - LHCN-M2 [nTPM]":"8.3","Cell RNA - MCF7 [nTPM]":"12.0","Cell RNA - MOLT-4 [nTPM]":"9.8","Cell RNA - NB-4 [nTPM]":"5.9","Cell RNA - NTERA-2 [nTPM]":"7.0","Cell RNA - OE19 [nTPM]":"15.3","Cell RNA - PC-3 [nTPM]":"8.9","Cell RNA - REH [nTPM]":"13.3","Cell RNA - RH-30 [nTPM]":"7.3","Cell RNA - RPMI-8226 [nTPM]":"12.6","Cell RNA - RPTEC TERT1 [nTPM]":"12.0","Cell RNA - RT4 [nTPM]":"8.5","Cell RNA - SCLC-21H [nTPM]":"4.1","Cell RNA - SH-SY5Y [nTPM]":"10.7","Cell RNA - SiHa [nTPM]":"16.2","Cell RNA - SK-BR-3 [nTPM]":"14.7","Cell RNA - SK-MEL-30 [nTPM]":"4.6","Cell RNA - SuSa [nTPM]":"8.4","Cell RNA - T-47d [nTPM]":"13.2","Cell RNA - THP-1 [nTPM]":"4.4","Cell RNA - TIME [nTPM]":"11.6","Cell RNA - U-138 MG [nTPM]":"12.8","Cell RNA - U-2 OS [nTPM]":"6.1","Cell RNA - U-2197 [nTPM]":"12.5","Cell RNA - U-251 MG [nTPM]":"10.9","Cell RNA - U-266\/70 [nTPM]":"3.3","Cell RNA - U-266\/84 [nTPM]":"4.5","Cell RNA - U-698 [nTPM]":"5.2","Cell RNA - U-87 MG [nTPM]":"13.9","Cell RNA - U-937 [nTPM]":"6.7","Cell RNA - WM-115 [nTPM]":"6.7","Blood RNA - basophil [nTPM]":"1.5","Blood RNA - classical monocyte [nTPM]":"2.2","Blood RNA - eosinophil [nTPM]":"2.5","Blood RNA - gdT-cell [nTPM]":"1.9","Blood RNA - intermediate monocyte [nTPM]":"2.3","Blood RNA - MAIT T-cell [nTPM]":"2.0","Blood RNA - memory B-cell [nTPM]":"2.1","Blood RNA - memory CD4 T-cell [nTPM]":"1.8","Blood RNA - memory CD8 T-cell [nTPM]":"1.6","Blood RNA - myeloid DC [nTPM]":"3.0","Blood RNA - naive B-cell [nTPM]":"1.5","Blood RNA - naive CD4 T-cell [nTPM]":"3.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"3.2","Blood RNA - non-classical monocyte [nTPM]":"1.8","Blood RNA - plasmacytoid DC [nTPM]":"3.2","Blood RNA - T-reg [nTPM]":"1.6","Blood RNA - total PBMC [nTPM]":"2.5","Brain RNA - amygdala [nTPM]":"3.5","Brain RNA - basal ganglia [nTPM]":"5.0","Brain RNA - cerebellum [nTPM]":"4.1","Brain RNA - cerebral cortex [nTPM]":"4.4","Brain RNA - hippocampal formation [nTPM]":"3.4","Brain RNA - hypothalamus [nTPM]":"3.5","Brain RNA - medulla oblongata [nTPM]":"3.9","Brain RNA - midbrain [nTPM]":"4.8","Brain RNA - pons [nTPM]":"4.2","Brain RNA - spinal cord [nTPM]":"3.0","Brain RNA - thalamus [nTPM]":"4.3","Brain RNA - white matter [nTPM]":"8.7","Single Cell Type RNA - Adipocytes [nTPM]":"2.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.2","Single Cell Type RNA - Astrocytes [nTPM]":"11.1","Single Cell Type RNA - B-cells [nTPM]":"2.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"5.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"0.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.5","Single Cell Type RNA - Endothelial cells [nTPM]":"2.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.5","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.1","Single Cell Type RNA - Fibroblasts [nTPM]":"3.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"5.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"19.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.4","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.2","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.4","Single Cell Type RNA - Leydig cells [nTPM]":"4.1","Single Cell Type RNA - Macrophages [nTPM]":"2.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"2.7","Single Cell Type RNA - Muller glia cells [nTPM]":"2.5","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.3","Single Cell Type RNA - Paneth cells [nTPM]":"6.7","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"2.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.6","Single Cell Type RNA - T-cells [nTPM]":"2.1","Single Cell Type RNA - Theca cells [nTPM]":"16.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.5","Single Cell Type RNA - Urothelial cells [nTPM]":"1.8"},{"Gene":"SIAE","Gene synonym":["CSE-C","LSE","MGC87009","YSG2"],"Ensembl":"ENSG00000110013","Gene description":"Sialic acid acetylesterase","Uniprot":["Q9HAT2"],"Chromosome":"11","Position":"124633113-124695707","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Serine esterase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"104.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"58.0","Cardiomyocytes":"59.5","Distal enterocytes":"102.4","Paneth cells":"53.0","Proximal enterocytes":"51.6","Undifferentiated cells":"63.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"7.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"88.6","ASC TERT1":"91.3","HSkMC":"98.9","OE19":"97.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038052","HPA038053"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2200000","Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038052":"AB_10671518","HPA038053":"AB_10673039"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.66e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.42e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Tissue RNA - adipose tissue [nTPM]":"18.7","Tissue RNA - adrenal gland [nTPM]":"17.3","Tissue RNA - amygdala [nTPM]":"16.8","Tissue RNA - appendix [nTPM]":"11.8","Tissue RNA - basal ganglia [nTPM]":"21.6","Tissue RNA - bone marrow [nTPM]":"3.7","Tissue RNA - breast [nTPM]":"15.9","Tissue RNA - cerebellum [nTPM]":"26.9","Tissue RNA - cerebral cortex [nTPM]":"19.8","Tissue RNA - cervix [nTPM]":"13.0","Tissue RNA - choroid plexus [nTPM]":"38.9","Tissue RNA - colon [nTPM]":"97.8","Tissue RNA - duodenum [nTPM]":"34.3","Tissue RNA - endometrium 1 [nTPM]":"7.1","Tissue RNA - epididymis [nTPM]":"34.3","Tissue RNA - esophagus [nTPM]":"13.6","Tissue RNA - fallopian tube [nTPM]":"19.3","Tissue RNA - gallbladder [nTPM]":"16.7","Tissue RNA - heart muscle [nTPM]":"43.8","Tissue RNA - hippocampal formation [nTPM]":"16.1","Tissue RNA - hypothalamus [nTPM]":"27.1","Tissue RNA - kidney [nTPM]":"62.1","Tissue RNA - liver [nTPM]":"43.4","Tissue RNA - lung [nTPM]":"20.6","Tissue RNA - lymph node [nTPM]":"5.8","Tissue RNA - medulla oblongata [nTPM]":"25.3","Tissue RNA - midbrain [nTPM]":"23.7","Tissue RNA - ovary [nTPM]":"5.7","Tissue RNA - pancreas [nTPM]":"17.3","Tissue RNA - parathyroid gland [nTPM]":"45.3","Tissue RNA - pituitary gland [nTPM]":"14.4","Tissue RNA - placenta [nTPM]":"11.8","Tissue RNA - pons [nTPM]":"24.7","Tissue RNA - prostate [nTPM]":"20.4","Tissue RNA - rectum [nTPM]":"104.4","Tissue RNA - retina [nTPM]":"6.2","Tissue RNA - salivary gland [nTPM]":"18.4","Tissue RNA - seminal vesicle [nTPM]":"15.3","Tissue RNA - skeletal muscle [nTPM]":"26.7","Tissue RNA - skin 1 [nTPM]":"13.0","Tissue RNA - small intestine [nTPM]":"35.8","Tissue RNA - smooth muscle [nTPM]":"10.4","Tissue RNA - spinal cord [nTPM]":"23.0","Tissue RNA - spleen [nTPM]":"9.1","Tissue RNA - stomach 1 [nTPM]":"19.0","Tissue RNA - testis [nTPM]":"10.3","Tissue RNA - thalamus [nTPM]":"24.9","Tissue RNA - thymus [nTPM]":"3.7","Tissue RNA - thyroid gland [nTPM]":"54.0","Tissue RNA - tongue [nTPM]":"33.3","Tissue RNA - tonsil [nTPM]":"6.7","Tissue RNA - urinary bladder [nTPM]":"16.8","Tissue RNA - vagina [nTPM]":"7.8","Tissue RNA - white matter [nTPM]":"26.3","Cell RNA - A-431 [nTPM]":"8.9","Cell RNA - A549 [nTPM]":"14.0","Cell RNA - AF22 [nTPM]":"8.0","Cell RNA - AN3-CA [nTPM]":"34.6","Cell RNA - ASC diff [nTPM]":"88.6","Cell RNA - ASC TERT1 [nTPM]":"91.3","Cell RNA - BEWO [nTPM]":"20.9","Cell RNA - BJ [nTPM]":"16.8","Cell RNA - BJ hTERT+ [nTPM]":"24.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.6","Cell RNA - CACO-2 [nTPM]":"10.9","Cell RNA - CAPAN-2 [nTPM]":"61.4","Cell RNA - Daudi [nTPM]":"5.5","Cell RNA - EFO-21 [nTPM]":"24.2","Cell RNA - fHDF\/TERT166 [nTPM]":"21.5","Cell RNA - GAMG [nTPM]":"9.4","Cell RNA - HaCaT [nTPM]":"17.3","Cell RNA - HAP1 [nTPM]":"12.8","Cell RNA - HBEC3-KT [nTPM]":"18.7","Cell RNA - HBF TERT88 [nTPM]":"4.2","Cell RNA - HDLM-2 [nTPM]":"26.0","Cell RNA - HEK 293 [nTPM]":"3.9","Cell RNA - HEL [nTPM]":"8.6","Cell RNA - HeLa [nTPM]":"3.7","Cell RNA - Hep G2 [nTPM]":"11.1","Cell RNA - HHSteC [nTPM]":"41.8","Cell RNA - HL-60 [nTPM]":"0.7","Cell RNA - HMC-1 [nTPM]":"7.2","Cell RNA - HSkMC [nTPM]":"98.9","Cell RNA - hTCEpi [nTPM]":"24.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.4","Cell RNA - hTERT-HME1 [nTPM]":"17.3","Cell RNA - hTERT-RPE1 [nTPM]":"58.5","Cell RNA - HUVEC TERT2 [nTPM]":"30.6","Cell RNA - JURKAT [nTPM]":"11.0","Cell RNA - K-562 [nTPM]":"7.1","Cell RNA - Karpas-707 [nTPM]":"37.5","Cell RNA - LHCN-M2 [nTPM]":"14.8","Cell RNA - MCF7 [nTPM]":"16.5","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"5.0","Cell RNA - OE19 [nTPM]":"97.7","Cell RNA - PC-3 [nTPM]":"28.5","Cell RNA - REH [nTPM]":"3.2","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"8.4","Cell RNA - RPTEC TERT1 [nTPM]":"51.4","Cell RNA - RT4 [nTPM]":"12.1","Cell RNA - SCLC-21H [nTPM]":"2.4","Cell RNA - SH-SY5Y [nTPM]":"5.1","Cell RNA - SiHa [nTPM]":"46.5","Cell RNA - SK-BR-3 [nTPM]":"18.6","Cell RNA - SK-MEL-30 [nTPM]":"8.0","Cell RNA - SuSa [nTPM]":"24.0","Cell RNA - T-47d [nTPM]":"36.8","Cell RNA - THP-1 [nTPM]":"3.2","Cell RNA - TIME [nTPM]":"34.1","Cell RNA - U-138 MG [nTPM]":"23.6","Cell RNA - U-2 OS [nTPM]":"4.3","Cell RNA - U-2197 [nTPM]":"26.5","Cell RNA - U-251 MG [nTPM]":"4.0","Cell RNA - U-266\/70 [nTPM]":"9.4","Cell RNA - U-266\/84 [nTPM]":"7.5","Cell RNA - U-698 [nTPM]":"0.7","Cell RNA - U-87 MG [nTPM]":"8.3","Cell RNA - U-937 [nTPM]":"4.6","Cell RNA - WM-115 [nTPM]":"9.8","Blood RNA - basophil [nTPM]":"7.6","Blood RNA - classical monocyte [nTPM]":"2.9","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"2.1","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"1.9","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.1","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"3.7","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"1.8","Brain RNA - amygdala [nTPM]":"16.8","Brain RNA - basal ganglia [nTPM]":"21.6","Brain RNA - cerebellum [nTPM]":"26.9","Brain RNA - cerebral cortex [nTPM]":"19.8","Brain RNA - hippocampal formation [nTPM]":"16.1","Brain RNA - hypothalamus [nTPM]":"27.1","Brain RNA - medulla oblongata [nTPM]":"25.3","Brain RNA - midbrain [nTPM]":"23.7","Brain RNA - pons [nTPM]":"24.7","Brain RNA - spinal cord [nTPM]":"23.0","Brain RNA - thalamus [nTPM]":"24.9","Brain RNA - white matter [nTPM]":"26.3","Single Cell Type RNA - Adipocytes [nTPM]":"4.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"58.0","Single Cell Type RNA - Astrocytes [nTPM]":"11.8","Single Cell Type RNA - B-cells [nTPM]":"2.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"6.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"59.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"9.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"102.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"15.2","Single Cell Type RNA - Early spermatids [nTPM]":"14.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.3","Single Cell Type RNA - Endothelial cells [nTPM]":"6.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.5","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.8","Single Cell Type RNA - Fibroblasts [nTPM]":"7.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"3.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.9","Single Cell Type RNA - Hepatocytes [nTPM]":"30.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.5","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"3.5","Single Cell Type RNA - Langerhans cells [nTPM]":"1.6","Single Cell Type RNA - Late spermatids [nTPM]":"12.0","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"4.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"4.5","Single Cell Type RNA - Muller glia cells [nTPM]":"1.9","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.2","Single Cell Type RNA - Paneth cells [nTPM]":"53.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"3.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"51.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"26.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.9","Single Cell Type RNA - Spermatocytes [nTPM]":"14.8","Single Cell Type RNA - Spermatogonia [nTPM]":"9.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.7","Single Cell Type RNA - T-cells [nTPM]":"2.0","Single Cell Type RNA - Theca cells [nTPM]":"8.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"63.6","Single Cell Type RNA - Urothelial cells [nTPM]":"7.1"},{"Gene":"SIK1","Gene synonym":["msk","SNF1LK"],"Ensembl":"ENSG00000142178","Gene description":"Salt inducible kinase 1","Uniprot":["P57059"],"Chromosome":"21","Position":"43414483-43427131","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Biological rhythms","Cell cycle","Differentiation"],"Molecular function":["Developmental protein","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Epilepsy","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"88.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"302.0","Basal respiratory cells":"123.5","Langerhans cells":"141.9","Suprabasal keratinocytes":"422.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HBEC3-KT":"35.3","HeLa":"63.1","hTCEpi":"45.4","LHCN-M2":"45.5","U-266\/84":"37.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB023801","HPA038211","HPA078064"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 28: Keratinocytes - Keratinization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB023801":null,"HPA038211":"AB_2675894","HPA078064":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Tissue RNA - adipose tissue [nTPM]":"24.5","Tissue RNA - adrenal gland [nTPM]":"8.3","Tissue RNA - amygdala [nTPM]":"0.7","Tissue RNA - appendix [nTPM]":"6.2","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"10.5","Tissue RNA - breast [nTPM]":"19.5","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"1.8","Tissue RNA - cervix [nTPM]":"17.5","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"7.0","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"4.4","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"18.5","Tissue RNA - fallopian tube [nTPM]":"18.6","Tissue RNA - gallbladder [nTPM]":"15.1","Tissue RNA - heart muscle [nTPM]":"16.0","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"5.1","Tissue RNA - liver [nTPM]":"20.9","Tissue RNA - lung [nTPM]":"12.7","Tissue RNA - lymph node [nTPM]":"4.3","Tissue RNA - medulla oblongata [nTPM]":"1.0","Tissue RNA - midbrain [nTPM]":"1.0","Tissue RNA - ovary [nTPM]":"26.9","Tissue RNA - pancreas [nTPM]":"11.8","Tissue RNA - parathyroid gland [nTPM]":"5.9","Tissue RNA - pituitary gland [nTPM]":"12.5","Tissue RNA - placenta [nTPM]":"12.5","Tissue RNA - pons [nTPM]":"0.8","Tissue RNA - prostate [nTPM]":"9.2","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"8.5","Tissue RNA - salivary gland [nTPM]":"12.1","Tissue RNA - seminal vesicle [nTPM]":"13.3","Tissue RNA - skeletal muscle [nTPM]":"13.0","Tissue RNA - skin 1 [nTPM]":"88.0","Tissue RNA - small intestine [nTPM]":"5.4","Tissue RNA - smooth muscle [nTPM]":"5.3","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"7.2","Tissue RNA - stomach 1 [nTPM]":"12.2","Tissue RNA - testis [nTPM]":"3.0","Tissue RNA - thalamus [nTPM]":"0.7","Tissue RNA - thymus [nTPM]":"11.0","Tissue RNA - thyroid gland [nTPM]":"6.2","Tissue RNA - tongue [nTPM]":"1.3","Tissue RNA - tonsil [nTPM]":"4.6","Tissue RNA - urinary bladder [nTPM]":"16.9","Tissue RNA - vagina [nTPM]":"14.4","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"1.2","Cell RNA - A549 [nTPM]":"3.4","Cell RNA - AF22 [nTPM]":"4.3","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.3","Cell RNA - ASC TERT1 [nTPM]":"1.6","Cell RNA - BEWO [nTPM]":"1.7","Cell RNA - BJ [nTPM]":"2.0","Cell RNA - BJ hTERT+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.7","Cell RNA - CACO-2 [nTPM]":"5.1","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"5.4","Cell RNA - EFO-21 [nTPM]":"1.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"19.8","Cell RNA - HaCaT [nTPM]":"23.6","Cell RNA - HAP1 [nTPM]":"3.5","Cell RNA - HBEC3-KT [nTPM]":"35.3","Cell RNA - HBF TERT88 [nTPM]":"2.0","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"1.1","Cell RNA - HEL [nTPM]":"1.6","Cell RNA - HeLa [nTPM]":"63.1","Cell RNA - Hep G2 [nTPM]":"2.0","Cell RNA - HHSteC [nTPM]":"4.8","Cell RNA - HL-60 [nTPM]":"1.7","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"2.1","Cell RNA - hTCEpi [nTPM]":"45.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.9","Cell RNA - hTERT-HME1 [nTPM]":"10.7","Cell RNA - hTERT-RPE1 [nTPM]":"20.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.7","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"45.5","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.9","Cell RNA - NB-4 [nTPM]":"3.9","Cell RNA - NTERA-2 [nTPM]":"1.9","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"3.4","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.8","Cell RNA - RPMI-8226 [nTPM]":"5.7","Cell RNA - RPTEC TERT1 [nTPM]":"4.0","Cell RNA - RT4 [nTPM]":"13.3","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"24.2","Cell RNA - SK-BR-3 [nTPM]":"4.0","Cell RNA - SK-MEL-30 [nTPM]":"0.8","Cell RNA - SuSa [nTPM]":"0.7","Cell RNA - T-47d [nTPM]":"2.3","Cell RNA - THP-1 [nTPM]":"0.6","Cell RNA - TIME [nTPM]":"8.1","Cell RNA - U-138 MG [nTPM]":"0.9","Cell RNA - U-2 OS [nTPM]":"4.2","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"9.5","Cell RNA - U-266\/84 [nTPM]":"37.7","Cell RNA - U-698 [nTPM]":"1.0","Cell RNA - U-87 MG [nTPM]":"10.0","Cell RNA - U-937 [nTPM]":"4.6","Cell RNA - WM-115 [nTPM]":"0.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.7","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"1.8","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"1.0","Brain RNA - midbrain [nTPM]":"1.0","Brain RNA - pons [nTPM]":"0.8","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.7","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"23.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"77.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"18.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"302.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"123.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.7","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"68.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - dendritic cells [nTPM]":"13.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.8","Single Cell Type RNA - Endothelial cells [nTPM]":"18.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"27.6","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.3","Single Cell Type RNA - Fibroblasts [nTPM]":"11.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"29.1","Single Cell Type RNA - granulocytes [nTPM]":"19.6","Single Cell Type RNA - Granulosa cells [nTPM]":"2.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.2","Single Cell Type RNA - Hepatocytes [nTPM]":"7.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.5","Single Cell Type RNA - Ionocytes [nTPM]":"85.5","Single Cell Type RNA - Kupffer cells [nTPM]":"3.8","Single Cell Type RNA - Langerhans cells [nTPM]":"141.9","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"10.1","Single Cell Type RNA - Melanocytes [nTPM]":"96.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.6","Single Cell Type RNA - Muller glia cells [nTPM]":"1.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.3","Single Cell Type RNA - Paneth cells [nTPM]":"24.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"36.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"50.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"35.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"422.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - T-cells [nTPM]":"16.4","Single Cell Type RNA - Theca cells [nTPM]":"0.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.3","Single Cell Type RNA - Urothelial cells [nTPM]":"1.2"},{"Gene":"SIK3","Gene synonym":["FLJ12240","KIAA0999","L19","QSK"],"Ensembl":"ENSG00000160584","Gene description":"SIK family kinase 3","Uniprot":["Q9Y2K2"],"Chromosome":"11","Position":"116843402-117098437","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"375.5","Excitatory neurons":"384.4","Inhibitory neurons":"399.6","Oligodendrocyte precursor cells":"457.9","Oligodendrocytes":"1679.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045245","HPA048161"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA045245":"AB_2679270","HPA048161":"AB_2680293"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.12e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.1","Tissue RNA - adrenal gland [nTPM]":"7.2","Tissue RNA - amygdala [nTPM]":"19.3","Tissue RNA - appendix [nTPM]":"11.4","Tissue RNA - basal ganglia [nTPM]":"36.6","Tissue RNA - bone marrow [nTPM]":"12.7","Tissue RNA - breast [nTPM]":"9.2","Tissue RNA - cerebellum [nTPM]":"15.0","Tissue RNA - cerebral cortex [nTPM]":"34.3","Tissue RNA - cervix [nTPM]":"9.6","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"11.7","Tissue RNA - duodenum [nTPM]":"8.5","Tissue RNA - endometrium 1 [nTPM]":"12.6","Tissue RNA - epididymis [nTPM]":"7.2","Tissue RNA - esophagus [nTPM]":"10.4","Tissue RNA - fallopian tube [nTPM]":"12.4","Tissue RNA - gallbladder [nTPM]":"9.8","Tissue RNA - heart muscle [nTPM]":"12.8","Tissue RNA - hippocampal formation [nTPM]":"19.7","Tissue RNA - hypothalamus [nTPM]":"19.4","Tissue RNA - kidney [nTPM]":"10.3","Tissue RNA - liver [nTPM]":"13.8","Tissue RNA - lung [nTPM]":"9.7","Tissue RNA - lymph node [nTPM]":"9.9","Tissue RNA - medulla oblongata [nTPM]":"22.0","Tissue RNA - midbrain [nTPM]":"23.1","Tissue RNA - ovary [nTPM]":"16.5","Tissue RNA - pancreas [nTPM]":"15.4","Tissue RNA - parathyroid gland [nTPM]":"17.7","Tissue RNA - pituitary gland [nTPM]":"10.0","Tissue RNA - placenta [nTPM]":"12.1","Tissue RNA - pons [nTPM]":"22.5","Tissue RNA - prostate [nTPM]":"8.2","Tissue RNA - rectum [nTPM]":"8.8","Tissue RNA - retina [nTPM]":"19.1","Tissue RNA - salivary gland [nTPM]":"9.8","Tissue RNA - seminal vesicle [nTPM]":"11.3","Tissue RNA - skeletal muscle [nTPM]":"19.5","Tissue RNA - skin 1 [nTPM]":"7.5","Tissue RNA - small intestine [nTPM]":"8.7","Tissue RNA - smooth muscle [nTPM]":"14.1","Tissue RNA - spinal cord [nTPM]":"11.5","Tissue RNA - spleen [nTPM]":"11.8","Tissue RNA - stomach 1 [nTPM]":"9.7","Tissue RNA - testis [nTPM]":"21.4","Tissue RNA - thalamus [nTPM]":"36.1","Tissue RNA - thymus [nTPM]":"12.3","Tissue RNA - thyroid gland [nTPM]":"17.1","Tissue RNA - tongue [nTPM]":"14.4","Tissue RNA - tonsil [nTPM]":"10.4","Tissue RNA - urinary bladder [nTPM]":"10.1","Tissue RNA - vagina [nTPM]":"7.5","Tissue RNA - white matter [nTPM]":"41.1","Cell RNA - A-431 [nTPM]":"11.8","Cell RNA - A549 [nTPM]":"8.9","Cell RNA - AF22 [nTPM]":"13.9","Cell RNA - AN3-CA [nTPM]":"14.7","Cell RNA - ASC diff [nTPM]":"11.7","Cell RNA - ASC TERT1 [nTPM]":"12.6","Cell RNA - BEWO [nTPM]":"22.2","Cell RNA - BJ [nTPM]":"8.8","Cell RNA - BJ hTERT+ [nTPM]":"15.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.6","Cell RNA - CACO-2 [nTPM]":"21.8","Cell RNA - CAPAN-2 [nTPM]":"13.3","Cell RNA - Daudi [nTPM]":"13.9","Cell RNA - EFO-21 [nTPM]":"14.0","Cell RNA - fHDF\/TERT166 [nTPM]":"16.3","Cell RNA - GAMG [nTPM]":"15.0","Cell RNA - HaCaT [nTPM]":"18.1","Cell RNA - HAP1 [nTPM]":"11.6","Cell RNA - HBEC3-KT [nTPM]":"12.7","Cell RNA - HBF TERT88 [nTPM]":"9.4","Cell RNA - HDLM-2 [nTPM]":"38.5","Cell RNA - HEK 293 [nTPM]":"7.4","Cell RNA - HEL [nTPM]":"31.2","Cell RNA - HeLa [nTPM]":"9.7","Cell RNA - Hep G2 [nTPM]":"13.6","Cell RNA - HHSteC [nTPM]":"10.9","Cell RNA - HL-60 [nTPM]":"11.2","Cell RNA - HMC-1 [nTPM]":"11.8","Cell RNA - HSkMC [nTPM]":"13.9","Cell RNA - hTCEpi [nTPM]":"7.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.5","Cell RNA - hTERT-HME1 [nTPM]":"23.3","Cell RNA - hTERT-RPE1 [nTPM]":"8.7","Cell RNA - HUVEC TERT2 [nTPM]":"9.2","Cell RNA - JURKAT [nTPM]":"9.0","Cell RNA - K-562 [nTPM]":"15.2","Cell RNA - Karpas-707 [nTPM]":"10.1","Cell RNA - LHCN-M2 [nTPM]":"9.4","Cell RNA - MCF7 [nTPM]":"4.0","Cell RNA - MOLT-4 [nTPM]":"10.2","Cell RNA - NB-4 [nTPM]":"12.1","Cell RNA - NTERA-2 [nTPM]":"7.7","Cell RNA - OE19 [nTPM]":"8.0","Cell RNA - PC-3 [nTPM]":"6.6","Cell RNA - REH [nTPM]":"12.9","Cell RNA - RH-30 [nTPM]":"8.0","Cell RNA - RPMI-8226 [nTPM]":"11.1","Cell RNA - RPTEC TERT1 [nTPM]":"9.3","Cell RNA - RT4 [nTPM]":"2.2","Cell RNA - SCLC-21H [nTPM]":"13.5","Cell RNA - SH-SY5Y [nTPM]":"10.8","Cell RNA - SiHa [nTPM]":"23.7","Cell RNA - SK-BR-3 [nTPM]":"10.3","Cell RNA - SK-MEL-30 [nTPM]":"4.4","Cell RNA - SuSa [nTPM]":"10.5","Cell RNA - T-47d [nTPM]":"6.8","Cell RNA - THP-1 [nTPM]":"11.8","Cell RNA - TIME [nTPM]":"10.6","Cell RNA - U-138 MG [nTPM]":"8.3","Cell RNA - U-2 OS [nTPM]":"10.4","Cell RNA - U-2197 [nTPM]":"14.0","Cell RNA - U-251 MG [nTPM]":"8.9","Cell RNA - U-266\/70 [nTPM]":"7.1","Cell RNA - U-266\/84 [nTPM]":"5.6","Cell RNA - U-698 [nTPM]":"17.5","Cell RNA - U-87 MG [nTPM]":"7.7","Cell RNA - U-937 [nTPM]":"18.2","Cell RNA - WM-115 [nTPM]":"11.4","Blood RNA - basophil [nTPM]":"2.0","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"1.5","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"19.3","Brain RNA - basal ganglia [nTPM]":"36.6","Brain RNA - cerebellum [nTPM]":"15.0","Brain RNA - cerebral cortex [nTPM]":"34.3","Brain RNA - hippocampal formation [nTPM]":"19.7","Brain RNA - hypothalamus [nTPM]":"19.4","Brain RNA - medulla oblongata [nTPM]":"22.0","Brain RNA - midbrain [nTPM]":"23.1","Brain RNA - pons [nTPM]":"22.5","Brain RNA - spinal cord [nTPM]":"11.5","Brain RNA - thalamus [nTPM]":"36.1","Brain RNA - white matter [nTPM]":"41.1","Single Cell Type RNA - Adipocytes [nTPM]":"25.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"22.1","Single Cell Type RNA - Astrocytes [nTPM]":"375.5","Single Cell Type RNA - B-cells [nTPM]":"34.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"26.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"26.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"42.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"22.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"12.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"112.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.7","Single Cell Type RNA - dendritic cells [nTPM]":"47.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.6","Single Cell Type RNA - Early spermatids [nTPM]":"89.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"64.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"27.9","Single Cell Type RNA - Endothelial cells [nTPM]":"20.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.3","Single Cell Type RNA - Erythroid cells [nTPM]":"12.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"384.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.8","Single Cell Type RNA - Fibroblasts [nTPM]":"22.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"71.5","Single Cell Type RNA - granulocytes [nTPM]":"17.2","Single Cell Type RNA - Granulosa cells [nTPM]":"37.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.2","Single Cell Type RNA - Hepatocytes [nTPM]":"26.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.7","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"399.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.1","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"21.7","Single Cell Type RNA - Langerhans cells [nTPM]":"45.1","Single Cell Type RNA - Late spermatids [nTPM]":"214.9","Single Cell Type RNA - Leydig cells [nTPM]":"10.2","Single Cell Type RNA - Macrophages [nTPM]":"31.4","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"161.1","Single Cell Type RNA - monocytes [nTPM]":"25.6","Single Cell Type RNA - Muller glia cells [nTPM]":"36.3","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"457.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1679.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.2","Single Cell Type RNA - Paneth cells [nTPM]":"8.2","Single Cell Type RNA - Peritubular cells [nTPM]":"14.3","Single Cell Type RNA - Plasma cells [nTPM]":"28.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"22.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"63.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"35.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.2","Single Cell Type RNA - Spermatocytes [nTPM]":"18.0","Single Cell Type RNA - Spermatogonia [nTPM]":"14.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"29.7","Single Cell Type RNA - T-cells [nTPM]":"44.2","Single Cell Type RNA - Theca cells [nTPM]":"14.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.4","Single Cell Type RNA - Urothelial cells [nTPM]":"30.0"},{"Gene":"SLC10A7","Gene synonym":["C4orf13","DKFZp313H0531","DKFZp566M114","DKFZp779O2438","MGC25043"],"Ensembl":"ENSG00000120519","Gene description":"Solute carrier family 10 member 7","Uniprot":["Q0GE19"],"Chromosome":"4","Position":"146253975-146521964","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Amelogenesis imperfecta","Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"44.4","Microglial cells":"50.6","Oligodendrocyte precursor cells":"62.4","Oligodendrocytes":"82.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039996"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039996":"AB_10673266"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.57e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.4","Tissue RNA - adrenal gland [nTPM]":"4.6","Tissue RNA - amygdala [nTPM]":"2.6","Tissue RNA - appendix [nTPM]":"4.9","Tissue RNA - basal ganglia [nTPM]":"4.0","Tissue RNA - bone marrow [nTPM]":"6.0","Tissue RNA - breast [nTPM]":"6.0","Tissue RNA - cerebellum [nTPM]":"3.2","Tissue RNA - cerebral cortex [nTPM]":"2.6","Tissue RNA - cervix [nTPM]":"7.2","Tissue RNA - choroid plexus [nTPM]":"1.7","Tissue RNA - colon [nTPM]":"7.0","Tissue RNA - duodenum [nTPM]":"4.6","Tissue RNA - endometrium 1 [nTPM]":"4.9","Tissue RNA - epididymis [nTPM]":"12.0","Tissue RNA - esophagus [nTPM]":"5.8","Tissue RNA - fallopian tube [nTPM]":"4.4","Tissue RNA - gallbladder [nTPM]":"5.6","Tissue RNA - heart muscle [nTPM]":"2.9","Tissue RNA - hippocampal formation [nTPM]":"2.9","Tissue RNA - hypothalamus [nTPM]":"3.6","Tissue RNA - kidney [nTPM]":"3.8","Tissue RNA - liver [nTPM]":"7.2","Tissue RNA - lung [nTPM]":"5.9","Tissue RNA - lymph node [nTPM]":"5.6","Tissue RNA - medulla oblongata [nTPM]":"4.6","Tissue RNA - midbrain [nTPM]":"3.8","Tissue RNA - ovary [nTPM]":"5.6","Tissue RNA - pancreas [nTPM]":"6.5","Tissue RNA - parathyroid gland [nTPM]":"3.7","Tissue RNA - pituitary gland [nTPM]":"3.6","Tissue RNA - placenta [nTPM]":"8.9","Tissue RNA - pons [nTPM]":"4.9","Tissue RNA - prostate [nTPM]":"6.3","Tissue RNA - rectum [nTPM]":"9.2","Tissue RNA - retina [nTPM]":"3.9","Tissue RNA - salivary gland [nTPM]":"6.9","Tissue RNA - seminal vesicle [nTPM]":"3.3","Tissue RNA - skeletal muscle [nTPM]":"2.2","Tissue RNA - skin 1 [nTPM]":"3.7","Tissue RNA - small intestine [nTPM]":"5.4","Tissue RNA - smooth muscle [nTPM]":"5.9","Tissue RNA - spinal cord [nTPM]":"3.8","Tissue RNA - spleen [nTPM]":"5.3","Tissue RNA - stomach 1 [nTPM]":"9.7","Tissue RNA - testis [nTPM]":"3.4","Tissue RNA - thalamus [nTPM]":"3.5","Tissue RNA - thymus [nTPM]":"6.5","Tissue RNA - thyroid gland [nTPM]":"7.0","Tissue RNA - tongue [nTPM]":"3.2","Tissue RNA - tonsil [nTPM]":"5.9","Tissue RNA - urinary bladder [nTPM]":"4.7","Tissue RNA - vagina [nTPM]":"4.8","Tissue RNA - white matter [nTPM]":"5.1","Cell RNA - A-431 [nTPM]":"5.2","Cell RNA - A549 [nTPM]":"1.7","Cell RNA - AF22 [nTPM]":"12.2","Cell RNA - AN3-CA [nTPM]":"5.0","Cell RNA - ASC diff [nTPM]":"8.6","Cell RNA - ASC TERT1 [nTPM]":"10.3","Cell RNA - BEWO [nTPM]":"5.8","Cell RNA - BJ [nTPM]":"6.3","Cell RNA - BJ hTERT+ [nTPM]":"8.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.8","Cell RNA - CACO-2 [nTPM]":"4.7","Cell RNA - CAPAN-2 [nTPM]":"21.6","Cell RNA - Daudi [nTPM]":"9.6","Cell RNA - EFO-21 [nTPM]":"4.4","Cell RNA - fHDF\/TERT166 [nTPM]":"6.9","Cell RNA - GAMG [nTPM]":"3.6","Cell RNA - HaCaT [nTPM]":"5.2","Cell RNA - HAP1 [nTPM]":"7.2","Cell RNA - HBEC3-KT [nTPM]":"8.6","Cell RNA - HBF TERT88 [nTPM]":"6.8","Cell RNA - HDLM-2 [nTPM]":"11.1","Cell RNA - HEK 293 [nTPM]":"3.5","Cell RNA - HEL [nTPM]":"11.8","Cell RNA - HeLa [nTPM]":"4.2","Cell RNA - Hep G2 [nTPM]":"8.5","Cell RNA - HHSteC [nTPM]":"5.5","Cell RNA - HL-60 [nTPM]":"20.5","Cell RNA - HMC-1 [nTPM]":"18.3","Cell RNA - HSkMC [nTPM]":"4.9","Cell RNA - hTCEpi [nTPM]":"6.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.9","Cell RNA - hTERT-HME1 [nTPM]":"8.7","Cell RNA - hTERT-RPE1 [nTPM]":"3.1","Cell RNA - HUVEC TERT2 [nTPM]":"10.2","Cell RNA - JURKAT [nTPM]":"10.2","Cell RNA - K-562 [nTPM]":"13.2","Cell RNA - Karpas-707 [nTPM]":"25.6","Cell RNA - LHCN-M2 [nTPM]":"4.3","Cell RNA - MCF7 [nTPM]":"3.6","Cell RNA - MOLT-4 [nTPM]":"15.6","Cell RNA - NB-4 [nTPM]":"5.2","Cell RNA - NTERA-2 [nTPM]":"2.2","Cell RNA - OE19 [nTPM]":"11.4","Cell RNA - PC-3 [nTPM]":"8.6","Cell RNA - REH [nTPM]":"8.6","Cell RNA - RH-30 [nTPM]":"8.9","Cell RNA - RPMI-8226 [nTPM]":"13.7","Cell RNA - RPTEC TERT1 [nTPM]":"4.0","Cell RNA - RT4 [nTPM]":"3.8","Cell RNA - SCLC-21H [nTPM]":"3.7","Cell RNA - SH-SY5Y [nTPM]":"3.1","Cell RNA - SiHa [nTPM]":"4.3","Cell RNA - SK-BR-3 [nTPM]":"12.8","Cell RNA - SK-MEL-30 [nTPM]":"5.3","Cell RNA - SuSa [nTPM]":"6.4","Cell RNA - T-47d [nTPM]":"7.5","Cell RNA - THP-1 [nTPM]":"8.1","Cell RNA - TIME [nTPM]":"5.8","Cell RNA - U-138 MG [nTPM]":"5.1","Cell RNA - U-2 OS [nTPM]":"5.4","Cell RNA - U-2197 [nTPM]":"7.8","Cell RNA - U-251 MG [nTPM]":"4.4","Cell RNA - U-266\/70 [nTPM]":"20.7","Cell RNA - U-266\/84 [nTPM]":"24.9","Cell RNA - U-698 [nTPM]":"13.4","Cell RNA - U-87 MG [nTPM]":"7.0","Cell RNA - U-937 [nTPM]":"8.2","Cell RNA - WM-115 [nTPM]":"7.4","Blood RNA - basophil [nTPM]":"10.9","Blood RNA - classical monocyte [nTPM]":"3.0","Blood RNA - eosinophil [nTPM]":"4.5","Blood RNA - gdT-cell [nTPM]":"3.7","Blood RNA - intermediate monocyte [nTPM]":"4.8","Blood RNA - MAIT T-cell [nTPM]":"3.8","Blood RNA - memory B-cell [nTPM]":"3.9","Blood RNA - memory CD4 T-cell [nTPM]":"3.7","Blood RNA - memory CD8 T-cell [nTPM]":"3.3","Blood RNA - myeloid DC [nTPM]":"4.0","Blood RNA - naive B-cell [nTPM]":"2.8","Blood RNA - naive CD4 T-cell [nTPM]":"3.5","Blood RNA - naive CD8 T-cell [nTPM]":"3.4","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"5.1","Blood RNA - non-classical monocyte [nTPM]":"3.9","Blood RNA - plasmacytoid DC [nTPM]":"2.7","Blood RNA - T-reg [nTPM]":"4.9","Blood RNA - total PBMC [nTPM]":"2.2","Brain RNA - amygdala [nTPM]":"2.6","Brain RNA - basal ganglia [nTPM]":"4.0","Brain RNA - cerebellum [nTPM]":"3.2","Brain RNA - cerebral cortex [nTPM]":"2.6","Brain RNA - hippocampal formation [nTPM]":"2.9","Brain RNA - hypothalamus [nTPM]":"3.6","Brain RNA - medulla oblongata [nTPM]":"4.6","Brain RNA - midbrain [nTPM]":"3.8","Brain RNA - pons [nTPM]":"4.9","Brain RNA - spinal cord [nTPM]":"3.8","Brain RNA - thalamus [nTPM]":"3.5","Brain RNA - white matter [nTPM]":"5.1","Single Cell Type RNA - Adipocytes [nTPM]":"10.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.9","Single Cell Type RNA - Astrocytes [nTPM]":"44.4","Single Cell Type RNA - B-cells [nTPM]":"7.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"6.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"3.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.4","Single Cell Type RNA - dendritic cells [nTPM]":"8.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.2","Single Cell Type RNA - Endothelial cells [nTPM]":"5.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"9.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"34.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.2","Single Cell Type RNA - Fibroblasts [nTPM]":"6.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.0","Single Cell Type RNA - granulocytes [nTPM]":"22.9","Single Cell Type RNA - Granulosa cells [nTPM]":"5.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.9","Single Cell Type RNA - Hepatocytes [nTPM]":"10.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.8","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.7","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"7.3","Single Cell Type RNA - Langerhans cells [nTPM]":"3.1","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"7.5","Single Cell Type RNA - Macrophages [nTPM]":"6.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"50.6","Single Cell Type RNA - monocytes [nTPM]":"4.9","Single Cell Type RNA - Muller glia cells [nTPM]":"3.4","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"62.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"82.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.6","Single Cell Type RNA - Paneth cells [nTPM]":"3.4","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"15.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.5","Single Cell Type RNA - Spermatocytes [nTPM]":"7.0","Single Cell Type RNA - Spermatogonia [nTPM]":"4.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.2","Single Cell Type RNA - T-cells [nTPM]":"8.6","Single Cell Type RNA - Theca cells [nTPM]":"2.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.6","Single Cell Type RNA - Urothelial cells [nTPM]":"4.1"},{"Gene":"SLC11A2","Gene synonym":["DCT1","DMT1","NRAMP2"],"Ensembl":"ENSG00000110911","Gene description":"Solute carrier family 11 member 2","Uniprot":["P49281"],"Chromosome":"12","Position":"50979401-51028566","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Iron transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Respiratory ciliated cells":"109.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032139","HPA032140"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA032139":"AB_10964213","HPA032140":"AB_10962932"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.07e-6"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Tissue RNA - adipose tissue [nTPM]":"12.1","Tissue RNA - adrenal gland [nTPM]":"17.0","Tissue RNA - amygdala [nTPM]":"12.8","Tissue RNA - appendix [nTPM]":"14.0","Tissue RNA - basal ganglia [nTPM]":"21.6","Tissue RNA - bone marrow [nTPM]":"15.9","Tissue RNA - breast [nTPM]":"30.3","Tissue RNA - cerebellum [nTPM]":"19.6","Tissue RNA - cerebral cortex [nTPM]":"18.1","Tissue RNA - cervix [nTPM]":"29.3","Tissue RNA - choroid plexus [nTPM]":"12.7","Tissue RNA - colon [nTPM]":"16.4","Tissue RNA - duodenum [nTPM]":"53.8","Tissue RNA - endometrium 1 [nTPM]":"15.7","Tissue RNA - epididymis [nTPM]":"17.6","Tissue RNA - esophagus [nTPM]":"23.9","Tissue RNA - fallopian tube [nTPM]":"21.4","Tissue RNA - gallbladder [nTPM]":"17.7","Tissue RNA - heart muscle [nTPM]":"14.7","Tissue RNA - hippocampal formation [nTPM]":"13.2","Tissue RNA - hypothalamus [nTPM]":"16.5","Tissue RNA - kidney [nTPM]":"22.5","Tissue RNA - liver [nTPM]":"25.6","Tissue RNA - lung [nTPM]":"23.2","Tissue RNA - lymph node [nTPM]":"10.3","Tissue RNA - medulla oblongata [nTPM]":"22.8","Tissue RNA - midbrain [nTPM]":"18.3","Tissue RNA - ovary [nTPM]":"12.8","Tissue RNA - pancreas [nTPM]":"22.6","Tissue RNA - parathyroid gland [nTPM]":"42.5","Tissue RNA - pituitary gland [nTPM]":"10.9","Tissue RNA - placenta [nTPM]":"23.7","Tissue RNA - pons [nTPM]":"22.9","Tissue RNA - prostate [nTPM]":"24.4","Tissue RNA - rectum [nTPM]":"16.2","Tissue RNA - retina [nTPM]":"23.1","Tissue RNA - salivary gland [nTPM]":"31.2","Tissue RNA - seminal vesicle [nTPM]":"19.3","Tissue RNA - skeletal muscle [nTPM]":"18.4","Tissue RNA - skin 1 [nTPM]":"20.3","Tissue RNA - small intestine [nTPM]":"13.8","Tissue RNA - smooth muscle [nTPM]":"15.3","Tissue RNA - spinal cord [nTPM]":"19.1","Tissue RNA - spleen [nTPM]":"8.7","Tissue RNA - stomach 1 [nTPM]":"17.8","Tissue RNA - testis [nTPM]":"13.3","Tissue RNA - thalamus [nTPM]":"18.5","Tissue RNA - thymus [nTPM]":"19.2","Tissue RNA - thyroid gland [nTPM]":"41.6","Tissue RNA - tongue [nTPM]":"20.3","Tissue RNA - tonsil [nTPM]":"17.2","Tissue RNA - urinary bladder [nTPM]":"20.4","Tissue RNA - vagina [nTPM]":"13.9","Tissue RNA - white matter [nTPM]":"31.1","Cell RNA - A-431 [nTPM]":"19.0","Cell RNA - A549 [nTPM]":"22.4","Cell RNA - AF22 [nTPM]":"31.4","Cell RNA - AN3-CA [nTPM]":"28.7","Cell RNA - ASC diff [nTPM]":"33.5","Cell RNA - ASC TERT1 [nTPM]":"28.6","Cell RNA - BEWO [nTPM]":"106.3","Cell RNA - BJ [nTPM]":"19.7","Cell RNA - BJ hTERT+ [nTPM]":"73.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.8","Cell RNA - CACO-2 [nTPM]":"30.6","Cell RNA - CAPAN-2 [nTPM]":"35.3","Cell RNA - Daudi [nTPM]":"11.8","Cell RNA - EFO-21 [nTPM]":"38.8","Cell RNA - fHDF\/TERT166 [nTPM]":"22.8","Cell RNA - GAMG [nTPM]":"35.7","Cell RNA - HaCaT [nTPM]":"25.3","Cell RNA - HAP1 [nTPM]":"26.6","Cell RNA - HBEC3-KT [nTPM]":"19.2","Cell RNA - HBF TERT88 [nTPM]":"21.9","Cell RNA - HDLM-2 [nTPM]":"17.1","Cell RNA - HEK 293 [nTPM]":"17.4","Cell RNA - HEL [nTPM]":"27.4","Cell RNA - HeLa [nTPM]":"29.2","Cell RNA - Hep G2 [nTPM]":"35.5","Cell RNA - HHSteC [nTPM]":"35.7","Cell RNA - HL-60 [nTPM]":"19.0","Cell RNA - HMC-1 [nTPM]":"54.5","Cell RNA - HSkMC [nTPM]":"31.6","Cell RNA - hTCEpi [nTPM]":"24.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.7","Cell RNA - hTERT-HME1 [nTPM]":"35.1","Cell RNA - hTERT-RPE1 [nTPM]":"45.6","Cell RNA - HUVEC TERT2 [nTPM]":"22.8","Cell RNA - JURKAT [nTPM]":"23.6","Cell RNA - K-562 [nTPM]":"24.4","Cell RNA - Karpas-707 [nTPM]":"5.6","Cell RNA - LHCN-M2 [nTPM]":"22.4","Cell RNA - MCF7 [nTPM]":"21.7","Cell RNA - MOLT-4 [nTPM]":"21.8","Cell RNA - NB-4 [nTPM]":"12.9","Cell RNA - NTERA-2 [nTPM]":"46.6","Cell RNA - OE19 [nTPM]":"19.8","Cell RNA - PC-3 [nTPM]":"15.5","Cell RNA - REH [nTPM]":"14.7","Cell RNA - RH-30 [nTPM]":"28.6","Cell RNA - RPMI-8226 [nTPM]":"21.1","Cell RNA - RPTEC TERT1 [nTPM]":"23.4","Cell RNA - RT4 [nTPM]":"27.7","Cell RNA - SCLC-21H [nTPM]":"21.6","Cell RNA - SH-SY5Y [nTPM]":"19.0","Cell RNA - SiHa [nTPM]":"16.3","Cell RNA - SK-BR-3 [nTPM]":"47.1","Cell RNA - SK-MEL-30 [nTPM]":"20.9","Cell RNA - SuSa [nTPM]":"36.2","Cell RNA - T-47d [nTPM]":"50.8","Cell RNA - THP-1 [nTPM]":"12.6","Cell RNA - TIME [nTPM]":"26.8","Cell RNA - U-138 MG [nTPM]":"19.2","Cell RNA - U-2 OS [nTPM]":"15.8","Cell RNA - U-2197 [nTPM]":"21.5","Cell RNA - U-251 MG [nTPM]":"10.9","Cell RNA - U-266\/70 [nTPM]":"14.1","Cell RNA - U-266\/84 [nTPM]":"20.4","Cell RNA - U-698 [nTPM]":"4.7","Cell RNA - U-87 MG [nTPM]":"54.1","Cell RNA - U-937 [nTPM]":"10.2","Cell RNA - WM-115 [nTPM]":"8.3","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"4.7","Blood RNA - eosinophil [nTPM]":"1.9","Blood RNA - gdT-cell [nTPM]":"4.2","Blood RNA - intermediate monocyte [nTPM]":"6.8","Blood RNA - MAIT T-cell [nTPM]":"3.7","Blood RNA - memory B-cell [nTPM]":"2.6","Blood RNA - memory CD4 T-cell [nTPM]":"3.3","Blood RNA - memory CD8 T-cell [nTPM]":"4.3","Blood RNA - myeloid DC [nTPM]":"7.0","Blood RNA - naive B-cell [nTPM]":"3.3","Blood RNA - naive CD4 T-cell [nTPM]":"4.6","Blood RNA - naive CD8 T-cell [nTPM]":"4.3","Blood RNA - neutrophil [nTPM]":"2.3","Blood RNA - NK-cell [nTPM]":"6.0","Blood RNA - non-classical monocyte [nTPM]":"4.8","Blood RNA - plasmacytoid DC [nTPM]":"2.9","Blood RNA - T-reg [nTPM]":"2.9","Blood RNA - total PBMC [nTPM]":"3.4","Brain RNA - amygdala [nTPM]":"12.8","Brain RNA - basal ganglia [nTPM]":"21.6","Brain RNA - cerebellum [nTPM]":"19.6","Brain RNA - cerebral cortex [nTPM]":"18.1","Brain RNA - hippocampal formation [nTPM]":"13.2","Brain RNA - hypothalamus [nTPM]":"16.5","Brain RNA - medulla oblongata [nTPM]":"22.8","Brain RNA - midbrain [nTPM]":"18.3","Brain RNA - pons [nTPM]":"22.9","Brain RNA - spinal cord [nTPM]":"19.1","Brain RNA - thalamus [nTPM]":"18.5","Brain RNA - white matter [nTPM]":"31.1","Single Cell Type RNA - Adipocytes [nTPM]":"9.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"46.1","Single Cell Type RNA - Astrocytes [nTPM]":"32.7","Single Cell Type RNA - B-cells [nTPM]":"6.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"84.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.2","Single Cell Type RNA - Bipolar cells [nTPM]":"26.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"37.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"69.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"57.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.0","Single Cell Type RNA - dendritic cells [nTPM]":"11.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"30.6","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"31.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.6","Single Cell Type RNA - Endothelial cells [nTPM]":"13.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.4","Single Cell Type RNA - Erythroid cells [nTPM]":"64.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"33.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"28.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"22.5","Single Cell Type RNA - Fibroblasts [nTPM]":"17.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"43.6","Single Cell Type RNA - granulocytes [nTPM]":"71.4","Single Cell Type RNA - Granulosa cells [nTPM]":"20.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.4","Single Cell Type RNA - Hepatocytes [nTPM]":"41.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"35.2","Single Cell Type RNA - Horizontal cells [nTPM]":"28.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"38.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.3","Single Cell Type RNA - Ionocytes [nTPM]":"42.7","Single Cell Type RNA - Kupffer cells [nTPM]":"16.9","Single Cell Type RNA - Langerhans cells [nTPM]":"25.4","Single Cell Type RNA - Late spermatids [nTPM]":"1.7","Single Cell Type RNA - Leydig cells [nTPM]":"9.6","Single Cell Type RNA - Macrophages [nTPM]":"30.1","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"26.2","Single Cell Type RNA - monocytes [nTPM]":"15.7","Single Cell Type RNA - Muller glia cells [nTPM]":"26.5","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"51.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"94.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.6","Single Cell Type RNA - Paneth cells [nTPM]":"15.0","Single Cell Type RNA - Peritubular cells [nTPM]":"8.6","Single Cell Type RNA - Plasma cells [nTPM]":"8.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"47.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"109.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.2","Single Cell Type RNA - Spermatocytes [nTPM]":"9.0","Single Cell Type RNA - Spermatogonia [nTPM]":"12.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"19.4","Single Cell Type RNA - T-cells [nTPM]":"10.7","Single Cell Type RNA - Theca cells [nTPM]":"10.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.0","Single Cell Type RNA - Urothelial cells [nTPM]":"23.1"},{"Gene":"SLC12A6","Gene synonym":["ACCPN","KCC3"],"Ensembl":"ENSG00000140199","Gene description":"Solute carrier family 12 member 6","Uniprot":["Q9UHW9"],"Chromosome":"15","Position":"34229784-34338060","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"85.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"15.2","neutrophil":"23.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"23.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"44.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034563"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA034563":"AB_10603887"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.33e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.4","Tissue RNA - adrenal gland [nTPM]":"4.0","Tissue RNA - amygdala [nTPM]":"5.9","Tissue RNA - appendix [nTPM]":"11.5","Tissue RNA - basal ganglia [nTPM]":"7.4","Tissue RNA - bone marrow [nTPM]":"26.8","Tissue RNA - breast [nTPM]":"5.5","Tissue RNA - cerebellum [nTPM]":"7.2","Tissue RNA - cerebral cortex [nTPM]":"7.9","Tissue RNA - cervix [nTPM]":"11.9","Tissue RNA - choroid plexus [nTPM]":"2.5","Tissue RNA - colon [nTPM]":"5.5","Tissue RNA - duodenum [nTPM]":"7.3","Tissue RNA - endometrium 1 [nTPM]":"5.2","Tissue RNA - epididymis [nTPM]":"7.0","Tissue RNA - esophagus [nTPM]":"18.8","Tissue RNA - fallopian tube [nTPM]":"4.6","Tissue RNA - gallbladder [nTPM]":"5.2","Tissue RNA - heart muscle [nTPM]":"7.3","Tissue RNA - hippocampal formation [nTPM]":"6.5","Tissue RNA - hypothalamus [nTPM]":"7.3","Tissue RNA - kidney [nTPM]":"15.9","Tissue RNA - liver [nTPM]":"3.9","Tissue RNA - lung [nTPM]":"9.1","Tissue RNA - lymph node [nTPM]":"10.1","Tissue RNA - medulla oblongata [nTPM]":"8.9","Tissue RNA - midbrain [nTPM]":"7.3","Tissue RNA - ovary [nTPM]":"4.2","Tissue RNA - pancreas [nTPM]":"3.5","Tissue RNA - parathyroid gland [nTPM]":"3.1","Tissue RNA - pituitary gland [nTPM]":"5.6","Tissue RNA - placenta [nTPM]":"4.3","Tissue RNA - pons [nTPM]":"9.3","Tissue RNA - prostate [nTPM]":"3.5","Tissue RNA - rectum [nTPM]":"6.1","Tissue RNA - retina [nTPM]":"31.1","Tissue RNA - salivary gland [nTPM]":"6.4","Tissue RNA - seminal vesicle [nTPM]":"3.8","Tissue RNA - skeletal muscle [nTPM]":"10.6","Tissue RNA - skin 1 [nTPM]":"7.6","Tissue RNA - small intestine [nTPM]":"9.1","Tissue RNA - smooth muscle [nTPM]":"4.9","Tissue RNA - spinal cord [nTPM]":"6.6","Tissue RNA - spleen [nTPM]":"12.9","Tissue RNA - stomach 1 [nTPM]":"6.7","Tissue RNA - testis [nTPM]":"25.9","Tissue RNA - thalamus [nTPM]":"7.7","Tissue RNA - thymus [nTPM]":"15.5","Tissue RNA - thyroid gland [nTPM]":"9.0","Tissue RNA - tongue [nTPM]":"10.9","Tissue RNA - tonsil [nTPM]":"11.6","Tissue RNA - urinary bladder [nTPM]":"8.3","Tissue RNA - vagina [nTPM]":"17.6","Tissue RNA - white matter [nTPM]":"8.4","Cell RNA - A-431 [nTPM]":"4.4","Cell RNA - A549 [nTPM]":"5.2","Cell RNA - AF22 [nTPM]":"3.1","Cell RNA - AN3-CA [nTPM]":"4.7","Cell RNA - ASC diff [nTPM]":"10.0","Cell RNA - ASC TERT1 [nTPM]":"11.4","Cell RNA - BEWO [nTPM]":"2.4","Cell RNA - BJ [nTPM]":"5.9","Cell RNA - BJ hTERT+ [nTPM]":"15.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.1","Cell RNA - CACO-2 [nTPM]":"3.1","Cell RNA - CAPAN-2 [nTPM]":"7.2","Cell RNA - Daudi [nTPM]":"3.1","Cell RNA - EFO-21 [nTPM]":"5.9","Cell RNA - fHDF\/TERT166 [nTPM]":"7.2","Cell RNA - GAMG [nTPM]":"4.3","Cell RNA - HaCaT [nTPM]":"44.0","Cell RNA - HAP1 [nTPM]":"7.9","Cell RNA - HBEC3-KT [nTPM]":"5.3","Cell RNA - HBF TERT88 [nTPM]":"5.8","Cell RNA - HDLM-2 [nTPM]":"1.2","Cell RNA - HEK 293 [nTPM]":"5.1","Cell RNA - HEL [nTPM]":"24.6","Cell RNA - HeLa [nTPM]":"14.0","Cell RNA - Hep G2 [nTPM]":"7.0","Cell RNA - HHSteC [nTPM]":"6.4","Cell RNA - HL-60 [nTPM]":"14.5","Cell RNA - HMC-1 [nTPM]":"24.6","Cell RNA - HSkMC [nTPM]":"6.9","Cell RNA - hTCEpi [nTPM]":"9.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.1","Cell RNA - hTERT-HME1 [nTPM]":"29.1","Cell RNA - hTERT-RPE1 [nTPM]":"10.9","Cell RNA - HUVEC TERT2 [nTPM]":"14.9","Cell RNA - JURKAT [nTPM]":"6.8","Cell RNA - K-562 [nTPM]":"5.4","Cell RNA - Karpas-707 [nTPM]":"6.8","Cell RNA - LHCN-M2 [nTPM]":"6.7","Cell RNA - MCF7 [nTPM]":"1.6","Cell RNA - MOLT-4 [nTPM]":"1.6","Cell RNA - NB-4 [nTPM]":"11.0","Cell RNA - NTERA-2 [nTPM]":"2.4","Cell RNA - OE19 [nTPM]":"3.8","Cell RNA - PC-3 [nTPM]":"5.7","Cell RNA - REH [nTPM]":"7.1","Cell RNA - RH-30 [nTPM]":"5.5","Cell RNA - RPMI-8226 [nTPM]":"3.3","Cell RNA - RPTEC TERT1 [nTPM]":"5.5","Cell RNA - RT4 [nTPM]":"11.2","Cell RNA - SCLC-21H [nTPM]":"7.2","Cell RNA - SH-SY5Y [nTPM]":"5.0","Cell RNA - SiHa [nTPM]":"7.1","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"1.5","Cell RNA - SuSa [nTPM]":"7.1","Cell RNA - T-47d [nTPM]":"2.8","Cell RNA - THP-1 [nTPM]":"4.8","Cell RNA - TIME [nTPM]":"9.4","Cell RNA - U-138 MG [nTPM]":"5.9","Cell RNA - U-2 OS [nTPM]":"4.2","Cell RNA - U-2197 [nTPM]":"21.0","Cell RNA - U-251 MG [nTPM]":"1.4","Cell RNA - U-266\/70 [nTPM]":"6.4","Cell RNA - U-266\/84 [nTPM]":"6.8","Cell RNA - U-698 [nTPM]":"1.9","Cell RNA - U-87 MG [nTPM]":"6.6","Cell RNA - U-937 [nTPM]":"10.5","Cell RNA - WM-115 [nTPM]":"2.2","Blood RNA - basophil [nTPM]":"15.2","Blood RNA - classical monocyte [nTPM]":"1.4","Blood RNA - eosinophil [nTPM]":"2.6","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"1.8","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"1.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"0.9","Blood RNA - naive B-cell [nTPM]":"2.4","Blood RNA - naive CD4 T-cell [nTPM]":"1.6","Blood RNA - naive CD8 T-cell [nTPM]":"1.4","Blood RNA - neutrophil [nTPM]":"23.4","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"0.8","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"3.2","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"5.9","Brain RNA - basal ganglia [nTPM]":"7.4","Brain RNA - cerebellum [nTPM]":"7.2","Brain RNA - cerebral cortex [nTPM]":"7.9","Brain RNA - hippocampal formation [nTPM]":"6.5","Brain RNA - hypothalamus [nTPM]":"7.3","Brain RNA - medulla oblongata [nTPM]":"8.9","Brain RNA - midbrain [nTPM]":"7.3","Brain RNA - pons [nTPM]":"9.3","Brain RNA - spinal cord [nTPM]":"6.6","Brain RNA - thalamus [nTPM]":"7.7","Brain RNA - white matter [nTPM]":"8.4","Single Cell Type RNA - Adipocytes [nTPM]":"16.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.0","Single Cell Type RNA - Astrocytes [nTPM]":"30.0","Single Cell Type RNA - B-cells [nTPM]":"32.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"15.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"4.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"85.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.2","Single Cell Type RNA - dendritic cells [nTPM]":"11.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.6","Single Cell Type RNA - Early spermatids [nTPM]":"15.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.4","Single Cell Type RNA - Endothelial cells [nTPM]":"17.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"35.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"47.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.6","Single Cell Type RNA - Fibroblasts [nTPM]":"7.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"22.4","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"8.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.1","Single Cell Type RNA - Hepatocytes [nTPM]":"7.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.2","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"52.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"37.1","Single Cell Type RNA - Langerhans cells [nTPM]":"3.8","Single Cell Type RNA - Late spermatids [nTPM]":"8.3","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"25.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"50.6","Single Cell Type RNA - monocytes [nTPM]":"34.5","Single Cell Type RNA - Muller glia cells [nTPM]":"8.7","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"40.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"58.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.1","Single Cell Type RNA - Paneth cells [nTPM]":"9.7","Single Cell Type RNA - Peritubular cells [nTPM]":"8.6","Single Cell Type RNA - Plasma cells [nTPM]":"29.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"56.6","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.0","Single Cell Type RNA - Spermatocytes [nTPM]":"39.9","Single Cell Type RNA - Spermatogonia [nTPM]":"21.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - T-cells [nTPM]":"18.0","Single Cell Type RNA - Theca cells [nTPM]":"4.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.4","Single Cell Type RNA - Urothelial cells [nTPM]":"43.6"},{"Gene":"SLC12A8","Gene synonym":["CCC9"],"Ensembl":"ENSG00000221955","Gene description":"Solute carrier family 12 member 8","Uniprot":["A0AV02"],"Chromosome":"3","Position":"125082636-125212864","Protein class":["Disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"thyroid gland":"22.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"23.9","Excitatory neurons":"38.4","granulocytes":"17.8","Inhibitory neurons":"27.8","Intestinal goblet cells":"36.6","Oligodendrocyte precursor cells":"31.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"19.6","HHSteC":"33.6","OE19":"27.6","U-2197":"67.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031123"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 27: Mucus-secreting cells - Mucin production","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA031123":"AB_2301872"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.56e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.5","Tissue RNA - adrenal gland [nTPM]":"1.1","Tissue RNA - amygdala [nTPM]":"2.9","Tissue RNA - appendix [nTPM]":"1.2","Tissue RNA - basal ganglia [nTPM]":"3.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"2.3","Tissue RNA - cerebellum [nTPM]":"1.0","Tissue RNA - cerebral cortex [nTPM]":"3.1","Tissue RNA - cervix [nTPM]":"1.4","Tissue RNA - choroid plexus [nTPM]":"11.7","Tissue RNA - colon [nTPM]":"3.5","Tissue RNA - duodenum [nTPM]":"5.6","Tissue RNA - endometrium 1 [nTPM]":"0.6","Tissue RNA - epididymis [nTPM]":"3.6","Tissue RNA - esophagus [nTPM]":"4.1","Tissue RNA - fallopian tube [nTPM]":"2.0","Tissue RNA - gallbladder [nTPM]":"8.3","Tissue RNA - heart muscle [nTPM]":"0.6","Tissue RNA - hippocampal formation [nTPM]":"3.4","Tissue RNA - hypothalamus [nTPM]":"2.4","Tissue RNA - kidney [nTPM]":"3.2","Tissue RNA - liver [nTPM]":"6.8","Tissue RNA - lung [nTPM]":"2.2","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"1.6","Tissue RNA - midbrain [nTPM]":"2.0","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"10.0","Tissue RNA - parathyroid gland [nTPM]":"4.3","Tissue RNA - pituitary gland [nTPM]":"2.2","Tissue RNA - placenta [nTPM]":"2.7","Tissue RNA - pons [nTPM]":"1.9","Tissue RNA - prostate [nTPM]":"2.8","Tissue RNA - rectum [nTPM]":"4.2","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"11.9","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"1.3","Tissue RNA - small intestine [nTPM]":"3.6","Tissue RNA - smooth muscle [nTPM]":"0.7","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"4.1","Tissue RNA - testis [nTPM]":"2.3","Tissue RNA - thalamus [nTPM]":"2.0","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"22.9","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.9","Tissue RNA - urinary bladder [nTPM]":"2.1","Tissue RNA - vagina [nTPM]":"2.2","Tissue RNA - white matter [nTPM]":"2.0","Cell RNA - A-431 [nTPM]":"14.7","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"2.7","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"3.3","Cell RNA - ASC TERT1 [nTPM]":"4.6","Cell RNA - BEWO [nTPM]":"6.7","Cell RNA - BJ [nTPM]":"0.8","Cell RNA - BJ hTERT+ [nTPM]":"2.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.7","Cell RNA - CACO-2 [nTPM]":"19.6","Cell RNA - CAPAN-2 [nTPM]":"6.8","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.9","Cell RNA - fHDF\/TERT166 [nTPM]":"5.6","Cell RNA - GAMG [nTPM]":"2.8","Cell RNA - HaCaT [nTPM]":"8.5","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.5","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"7.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"33.6","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.0","Cell RNA - HSkMC [nTPM]":"8.7","Cell RNA - hTCEpi [nTPM]":"8.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.9","Cell RNA - hTERT-HME1 [nTPM]":"0.9","Cell RNA - hTERT-RPE1 [nTPM]":"16.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.6","Cell RNA - LHCN-M2 [nTPM]":"1.3","Cell RNA - MCF7 [nTPM]":"3.9","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"9.3","Cell RNA - OE19 [nTPM]":"27.6","Cell RNA - PC-3 [nTPM]":"0.7","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"6.8","Cell RNA - RT4 [nTPM]":"1.3","Cell RNA - SCLC-21H [nTPM]":"4.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"7.0","Cell RNA - SK-BR-3 [nTPM]":"8.4","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.9","Cell RNA - T-47d [nTPM]":"15.6","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"1.3","Cell RNA - U-2197 [nTPM]":"67.9","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"1.9","Cell RNA - U-698 [nTPM]":"5.0","Cell RNA - U-87 MG [nTPM]":"3.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.4","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.9","Brain RNA - basal ganglia [nTPM]":"3.2","Brain RNA - cerebellum [nTPM]":"1.0","Brain RNA - cerebral cortex [nTPM]":"3.1","Brain RNA - hippocampal formation [nTPM]":"3.4","Brain RNA - hypothalamus [nTPM]":"2.4","Brain RNA - medulla oblongata [nTPM]":"1.6","Brain RNA - midbrain [nTPM]":"2.0","Brain RNA - pons [nTPM]":"1.9","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"2.0","Brain RNA - white matter [nTPM]":"2.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"7.2","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"2.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"38.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.5","Single Cell Type RNA - Fibroblasts [nTPM]":"2.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.7","Single Cell Type RNA - granulocytes [nTPM]":"17.8","Single Cell Type RNA - Granulosa cells [nTPM]":"1.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"9.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"27.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"36.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"2.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"31.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.9","Single Cell Type RNA - Paneth cells [nTPM]":"3.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.0","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.6","Single Cell Type RNA - Urothelial cells [nTPM]":"1.0"},{"Gene":"SLC13A3","Gene synonym":["NADC3","SDCT2"],"Ensembl":"ENSG00000158296","Gene description":"Solute carrier family 13 member 3","Uniprot":["Q8WWT9"],"Chromosome":"20","Position":"46557823-46684467","Protein class":["Disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"kidney":"407.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"53.8","Cytotrophoblasts":"106.6","Excitatory neurons":"65.0","Oligodendrocytes":"178.1","Proximal tubular cells":"245.9","Syncytiotrophoblasts":"79.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"11.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"16.1","EFO-21":"18.8","Hep G2":"56.1","HHSteC":"18.4","K-562":"15.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014333","HPA014353","HPA014736"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA014333":"AB_2732407","HPA014353":"AB_1856968","HPA014736":"AB_1856970"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.3","Tissue RNA - adrenal gland [nTPM]":"2.4","Tissue RNA - amygdala [nTPM]":"12.5","Tissue RNA - appendix [nTPM]":"0.7","Tissue RNA - basal ganglia [nTPM]":"22.8","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"1.9","Tissue RNA - cerebellum [nTPM]":"16.5","Tissue RNA - cerebral cortex [nTPM]":"16.1","Tissue RNA - cervix [nTPM]":"2.0","Tissue RNA - choroid plexus [nTPM]":"4.9","Tissue RNA - colon [nTPM]":"0.8","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"1.8","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"0.9","Tissue RNA - fallopian tube [nTPM]":"2.4","Tissue RNA - gallbladder [nTPM]":"1.9","Tissue RNA - heart muscle [nTPM]":"1.0","Tissue RNA - hippocampal formation [nTPM]":"10.1","Tissue RNA - hypothalamus [nTPM]":"16.2","Tissue RNA - kidney [nTPM]":"407.6","Tissue RNA - liver [nTPM]":"21.7","Tissue RNA - lung [nTPM]":"1.4","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"18.3","Tissue RNA - midbrain [nTPM]":"19.5","Tissue RNA - ovary [nTPM]":"4.5","Tissue RNA - pancreas [nTPM]":"9.0","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"2.6","Tissue RNA - placenta [nTPM]":"43.2","Tissue RNA - pons [nTPM]":"19.0","Tissue RNA - prostate [nTPM]":"6.3","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"1.1","Tissue RNA - salivary gland [nTPM]":"4.9","Tissue RNA - seminal vesicle [nTPM]":"0.8","Tissue RNA - skeletal muscle [nTPM]":"1.0","Tissue RNA - skin 1 [nTPM]":"2.2","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"1.9","Tissue RNA - spinal cord [nTPM]":"12.5","Tissue RNA - spleen [nTPM]":"0.6","Tissue RNA - stomach 1 [nTPM]":"4.7","Tissue RNA - testis [nTPM]":"8.7","Tissue RNA - thalamus [nTPM]":"19.9","Tissue RNA - thymus [nTPM]":"1.1","Tissue RNA - thyroid gland [nTPM]":"1.4","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"0.7","Tissue RNA - urinary bladder [nTPM]":"1.8","Tissue RNA - vagina [nTPM]":"1.4","Tissue RNA - white matter [nTPM]":"37.4","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"1.6","Cell RNA - AN3-CA [nTPM]":"5.6","Cell RNA - ASC diff [nTPM]":"8.3","Cell RNA - ASC TERT1 [nTPM]":"7.7","Cell RNA - BEWO [nTPM]":"16.1","Cell RNA - BJ [nTPM]":"3.5","Cell RNA - BJ hTERT+ [nTPM]":"2.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.4","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"18.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"2.1","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"2.6","Cell RNA - HBF TERT88 [nTPM]":"4.5","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"6.8","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"56.1","Cell RNA - HHSteC [nTPM]":"18.4","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"4.8","Cell RNA - HSkMC [nTPM]":"10.5","Cell RNA - hTCEpi [nTPM]":"7.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.9","Cell RNA - hTERT-HME1 [nTPM]":"5.4","Cell RNA - hTERT-RPE1 [nTPM]":"5.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"15.3","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.6","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.7","Cell RNA - NTERA-2 [nTPM]":"10.3","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"1.2","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"4.0","Cell RNA - SK-MEL-30 [nTPM]":"0.8","Cell RNA - SuSa [nTPM]":"1.0","Cell RNA - T-47d [nTPM]":"2.9","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"4.0","Cell RNA - U-2197 [nTPM]":"8.7","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"1.2","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.6","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"12.5","Brain RNA - basal ganglia [nTPM]":"22.8","Brain RNA - cerebellum [nTPM]":"16.5","Brain RNA - cerebral cortex [nTPM]":"16.1","Brain RNA - hippocampal formation [nTPM]":"10.1","Brain RNA - hypothalamus [nTPM]":"16.2","Brain RNA - medulla oblongata [nTPM]":"18.3","Brain RNA - midbrain [nTPM]":"19.5","Brain RNA - pons [nTPM]":"19.0","Brain RNA - spinal cord [nTPM]":"12.5","Brain RNA - thalamus [nTPM]":"19.9","Brain RNA - white matter [nTPM]":"37.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.2","Single Cell Type RNA - Astrocytes [nTPM]":"53.8","Single Cell Type RNA - B-cells [nTPM]":"3.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"106.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"23.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"65.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.1","Single Cell Type RNA - Fibroblasts [nTPM]":"2.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"17.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"40.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"27.8","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"2.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"24.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"178.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"1.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"245.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.0","Single Cell Type RNA - Spermatocytes [nTPM]":"6.6","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"79.4","Single Cell Type RNA - T-cells [nTPM]":"1.5","Single Cell Type RNA - Theca cells [nTPM]":"2.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"SLC13A5","Gene synonym":["INDY","NACT"],"Ensembl":"ENSG00000141485","Gene description":"Solute carrier family 13 member 5","Uniprot":["Q86YT5"],"Chromosome":"17","Position":"6684719-6713377","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Amelogenesis imperfecta","Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"liver":"414.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"Hepatocytes":"381.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"15","RNA cancer specific FPKM":{"liver cancer":"27.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"79","RNA cell line specific nTPM":{"Hep G2":"58.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044343"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA044343":"AB_10961771"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.79e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"2.7","Tissue RNA - amygdala [nTPM]":"4.8","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"7.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"4.8","Tissue RNA - cerebral cortex [nTPM]":"8.0","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"2.7","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"1.1","Tissue RNA - fallopian tube [nTPM]":"2.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"5.3","Tissue RNA - hypothalamus [nTPM]":"7.9","Tissue RNA - kidney [nTPM]":"0.7","Tissue RNA - liver [nTPM]":"414.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"6.8","Tissue RNA - midbrain [nTPM]":"6.1","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"5.4","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"1.7","Tissue RNA - salivary gland [nTPM]":"38.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"4.8","Tissue RNA - spleen [nTPM]":"3.3","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"2.3","Tissue RNA - thalamus [nTPM]":"8.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"3.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.5","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"58.0","Cell RNA - HHSteC [nTPM]":"0.5","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.7","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.8","Brain RNA - basal ganglia [nTPM]":"7.0","Brain RNA - cerebellum [nTPM]":"4.8","Brain RNA - cerebral cortex [nTPM]":"8.0","Brain RNA - hippocampal formation [nTPM]":"5.3","Brain RNA - hypothalamus [nTPM]":"7.9","Brain RNA - medulla oblongata [nTPM]":"6.8","Brain RNA - midbrain [nTPM]":"6.1","Brain RNA - pons [nTPM]":"5.4","Brain RNA - spinal cord [nTPM]":"4.8","Brain RNA - thalamus [nTPM]":"8.4","Brain RNA - white matter [nTPM]":"3.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"24.8","Single Cell Type RNA - B-cells [nTPM]":"4.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"24.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.8","Single Cell Type RNA - Hepatocytes [nTPM]":"381.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"23.2","Single Cell Type RNA - Langerhans cells [nTPM]":"1.1","Single Cell Type RNA - Late spermatids [nTPM]":"0.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"7.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"2.4","Single Cell Type RNA - Spermatogonia [nTPM]":"2.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"7.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"SLC16A1","Gene synonym":["MCT","MCT1"],"Ensembl":"ENSG00000155380","Gene description":"Solute carrier family 16 member 1","Uniprot":["P53985"],"Chromosome":"1","Position":"112911847-112957593","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"158.4","Granulosa cells":"322.8","Muller glia cells":"184.8","Rod photoreceptor cells":"277.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"6.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003324","CAB017489","HPA071055","CAB079035"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"CAB017489":"AB_2189197","CAB079035":null,"HPA003324":"AB_1856982","HPA071055":"AB_2686337"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.37e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.05e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.10e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.78e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-3"},"Tissue RNA - adipose tissue [nTPM]":"20.7","Tissue RNA - adrenal gland [nTPM]":"10.4","Tissue RNA - amygdala [nTPM]":"35.7","Tissue RNA - appendix [nTPM]":"11.8","Tissue RNA - basal ganglia [nTPM]":"36.1","Tissue RNA - bone marrow [nTPM]":"4.3","Tissue RNA - breast [nTPM]":"7.5","Tissue RNA - cerebellum [nTPM]":"37.8","Tissue RNA - cerebral cortex [nTPM]":"99.4","Tissue RNA - cervix [nTPM]":"7.1","Tissue RNA - choroid plexus [nTPM]":"37.8","Tissue RNA - colon [nTPM]":"46.8","Tissue RNA - duodenum [nTPM]":"32.5","Tissue RNA - endometrium 1 [nTPM]":"28.6","Tissue RNA - epididymis [nTPM]":"22.8","Tissue RNA - esophagus [nTPM]":"15.3","Tissue RNA - fallopian tube [nTPM]":"13.1","Tissue RNA - gallbladder [nTPM]":"14.8","Tissue RNA - heart muscle [nTPM]":"67.9","Tissue RNA - hippocampal formation [nTPM]":"33.5","Tissue RNA - hypothalamus [nTPM]":"35.2","Tissue RNA - kidney [nTPM]":"11.4","Tissue RNA - liver [nTPM]":"55.6","Tissue RNA - lung [nTPM]":"4.9","Tissue RNA - lymph node [nTPM]":"9.5","Tissue RNA - medulla oblongata [nTPM]":"38.6","Tissue RNA - midbrain [nTPM]":"35.9","Tissue RNA - ovary [nTPM]":"7.9","Tissue RNA - pancreas [nTPM]":"2.0","Tissue RNA - parathyroid gland [nTPM]":"10.0","Tissue RNA - pituitary gland [nTPM]":"5.2","Tissue RNA - placenta [nTPM]":"34.0","Tissue RNA - pons [nTPM]":"37.0","Tissue RNA - prostate [nTPM]":"14.4","Tissue RNA - rectum [nTPM]":"35.3","Tissue RNA - retina [nTPM]":"68.9","Tissue RNA - salivary gland [nTPM]":"3.5","Tissue RNA - seminal vesicle [nTPM]":"11.2","Tissue RNA - skeletal muscle [nTPM]":"67.5","Tissue RNA - skin 1 [nTPM]":"13.0","Tissue RNA - small intestine [nTPM]":"16.6","Tissue RNA - smooth muscle [nTPM]":"39.2","Tissue RNA - spinal cord [nTPM]":"37.0","Tissue RNA - spleen [nTPM]":"6.6","Tissue RNA - stomach 1 [nTPM]":"26.6","Tissue RNA - testis [nTPM]":"29.8","Tissue RNA - thalamus [nTPM]":"38.3","Tissue RNA - thymus [nTPM]":"11.7","Tissue RNA - thyroid gland [nTPM]":"8.6","Tissue RNA - tongue [nTPM]":"59.6","Tissue RNA - tonsil [nTPM]":"11.6","Tissue RNA - urinary bladder [nTPM]":"11.9","Tissue RNA - vagina [nTPM]":"7.1","Tissue RNA - white matter [nTPM]":"38.2","Cell RNA - A-431 [nTPM]":"111.1","Cell RNA - A549 [nTPM]":"24.0","Cell RNA - AF22 [nTPM]":"86.9","Cell RNA - AN3-CA [nTPM]":"74.3","Cell RNA - ASC diff [nTPM]":"61.9","Cell RNA - ASC TERT1 [nTPM]":"52.1","Cell RNA - BEWO [nTPM]":"272.7","Cell RNA - BJ [nTPM]":"64.6","Cell RNA - BJ hTERT+ [nTPM]":"51.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"52.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"80.9","Cell RNA - CACO-2 [nTPM]":"85.4","Cell RNA - CAPAN-2 [nTPM]":"67.1","Cell RNA - Daudi [nTPM]":"113.8","Cell RNA - EFO-21 [nTPM]":"82.3","Cell RNA - fHDF\/TERT166 [nTPM]":"61.6","Cell RNA - GAMG [nTPM]":"32.6","Cell RNA - HaCaT [nTPM]":"113.1","Cell RNA - HAP1 [nTPM]":"126.3","Cell RNA - HBEC3-KT [nTPM]":"124.8","Cell RNA - HBF TERT88 [nTPM]":"96.8","Cell RNA - HDLM-2 [nTPM]":"75.6","Cell RNA - HEK 293 [nTPM]":"105.2","Cell RNA - HEL [nTPM]":"108.9","Cell RNA - HeLa [nTPM]":"63.4","Cell RNA - Hep G2 [nTPM]":"112.9","Cell RNA - HHSteC [nTPM]":"104.6","Cell RNA - HL-60 [nTPM]":"123.2","Cell RNA - HMC-1 [nTPM]":"9.9","Cell RNA - HSkMC [nTPM]":"72.2","Cell RNA - hTCEpi [nTPM]":"144.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"75.7","Cell RNA - hTERT-HME1 [nTPM]":"146.4","Cell RNA - hTERT-RPE1 [nTPM]":"79.2","Cell RNA - HUVEC TERT2 [nTPM]":"131.4","Cell RNA - JURKAT [nTPM]":"53.8","Cell RNA - K-562 [nTPM]":"131.3","Cell RNA - Karpas-707 [nTPM]":"78.0","Cell RNA - LHCN-M2 [nTPM]":"61.9","Cell RNA - MCF7 [nTPM]":"19.9","Cell RNA - MOLT-4 [nTPM]":"70.2","Cell RNA - NB-4 [nTPM]":"70.1","Cell RNA - NTERA-2 [nTPM]":"271.4","Cell RNA - OE19 [nTPM]":"36.7","Cell RNA - PC-3 [nTPM]":"74.5","Cell RNA - REH [nTPM]":"67.9","Cell RNA - RH-30 [nTPM]":"130.7","Cell RNA - RPMI-8226 [nTPM]":"92.8","Cell RNA - RPTEC TERT1 [nTPM]":"67.3","Cell RNA - RT4 [nTPM]":"1.9","Cell RNA - SCLC-21H [nTPM]":"86.9","Cell RNA - SH-SY5Y [nTPM]":"46.5","Cell RNA - SiHa [nTPM]":"121.8","Cell RNA - SK-BR-3 [nTPM]":"3.8","Cell RNA - SK-MEL-30 [nTPM]":"97.5","Cell RNA - SuSa [nTPM]":"130.0","Cell RNA - T-47d [nTPM]":"3.7","Cell RNA - THP-1 [nTPM]":"48.9","Cell RNA - TIME [nTPM]":"80.9","Cell RNA - U-138 MG [nTPM]":"45.4","Cell RNA - U-2 OS [nTPM]":"72.0","Cell RNA - U-2197 [nTPM]":"89.3","Cell RNA - U-251 MG [nTPM]":"93.1","Cell RNA - U-266\/70 [nTPM]":"39.7","Cell RNA - U-266\/84 [nTPM]":"33.9","Cell RNA - U-698 [nTPM]":"116.7","Cell RNA - U-87 MG [nTPM]":"137.1","Cell RNA - U-937 [nTPM]":"78.5","Cell RNA - WM-115 [nTPM]":"56.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.4","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"1.6","Blood RNA - MAIT T-cell [nTPM]":"1.7","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.8","Blood RNA - memory CD8 T-cell [nTPM]":"2.0","Blood RNA - myeloid DC [nTPM]":"2.5","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"6.1","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"35.7","Brain RNA - basal ganglia [nTPM]":"36.1","Brain RNA - cerebellum [nTPM]":"37.8","Brain RNA - cerebral cortex [nTPM]":"99.4","Brain RNA - hippocampal formation [nTPM]":"33.5","Brain RNA - hypothalamus [nTPM]":"35.2","Brain RNA - medulla oblongata [nTPM]":"38.6","Brain RNA - midbrain [nTPM]":"35.9","Brain RNA - pons [nTPM]":"37.0","Brain RNA - spinal cord [nTPM]":"37.0","Brain RNA - thalamus [nTPM]":"38.3","Brain RNA - white matter [nTPM]":"38.2","Single Cell Type RNA - Adipocytes [nTPM]":"15.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.6","Single Cell Type RNA - Astrocytes [nTPM]":"8.5","Single Cell Type RNA - B-cells [nTPM]":"16.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"89.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"39.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"87.6","Single Cell Type RNA - Bipolar cells [nTPM]":"16.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"126.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"5.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"158.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"77.4","Single Cell Type RNA - dendritic cells [nTPM]":"20.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"99.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.5","Single Cell Type RNA - Early spermatids [nTPM]":"107.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"70.7","Single Cell Type RNA - Endothelial cells [nTPM]":"22.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.5","Single Cell Type RNA - Erythroid cells [nTPM]":"20.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"67.6","Single Cell Type RNA - Fibroblasts [nTPM]":"32.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"67.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"35.8","Single Cell Type RNA - granulocytes [nTPM]":"8.9","Single Cell Type RNA - Granulosa cells [nTPM]":"322.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"37.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.4","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.3","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"9.0","Single Cell Type RNA - Langerhans cells [nTPM]":"15.7","Single Cell Type RNA - Late spermatids [nTPM]":"118.3","Single Cell Type RNA - Leydig cells [nTPM]":"11.8","Single Cell Type RNA - Macrophages [nTPM]":"12.8","Single Cell Type RNA - Melanocytes [nTPM]":"39.2","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"4.3","Single Cell Type RNA - Muller glia cells [nTPM]":"184.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"23.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.4","Single Cell Type RNA - Paneth cells [nTPM]":"7.7","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"25.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"277.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"38.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.1","Single Cell Type RNA - Spermatocytes [nTPM]":"45.3","Single Cell Type RNA - Spermatogonia [nTPM]":"23.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"29.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"39.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"46.0","Single Cell Type RNA - T-cells [nTPM]":"20.9","Single Cell Type RNA - Theca cells [nTPM]":"49.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.3","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"SLC16A11","Gene synonym":["FLJ90193","MCT11"],"Ensembl":"ENSG00000174326","Gene description":"Solute carrier family 16 member 11","Uniprot":["Q8NCK7"],"Chromosome":"17","Position":"7041621-7044092","Protein class":["Disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Lipid metabolism","Symport","Transport"],"Molecular function":null,"Disease involvement":["Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"thyroid gland":"13.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"12.8","Muller glia cells":"32.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"12.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"B-cells":"1.0","T-cells":"1.5"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 5: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.56e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.45e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.19e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.5","Tissue RNA - adrenal gland [nTPM]":"0.7","Tissue RNA - amygdala [nTPM]":"1.4","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"1.4","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"3.7","Tissue RNA - cerebellum [nTPM]":"2.2","Tissue RNA - cerebral cortex [nTPM]":"1.9","Tissue RNA - cervix [nTPM]":"1.9","Tissue RNA - choroid plexus [nTPM]":"7.1","Tissue RNA - colon [nTPM]":"1.3","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"1.3","Tissue RNA - epididymis [nTPM]":"1.4","Tissue RNA - esophagus [nTPM]":"2.3","Tissue RNA - fallopian tube [nTPM]":"12.8","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"3.0","Tissue RNA - hippocampal formation [nTPM]":"1.4","Tissue RNA - hypothalamus [nTPM]":"2.0","Tissue RNA - kidney [nTPM]":"4.7","Tissue RNA - liver [nTPM]":"9.6","Tissue RNA - lung [nTPM]":"2.8","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"1.6","Tissue RNA - midbrain [nTPM]":"1.8","Tissue RNA - ovary [nTPM]":"2.6","Tissue RNA - pancreas [nTPM]":"4.0","Tissue RNA - parathyroid gland [nTPM]":"5.4","Tissue RNA - pituitary gland [nTPM]":"4.8","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"2.0","Tissue RNA - prostate [nTPM]":"3.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"10.4","Tissue RNA - seminal vesicle [nTPM]":"1.9","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"6.0","Tissue RNA - small intestine [nTPM]":"1.8","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"2.1","Tissue RNA - spleen [nTPM]":"1.8","Tissue RNA - stomach 1 [nTPM]":"1.3","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"1.1","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"13.5","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.9","Tissue RNA - vagina [nTPM]":"1.8","Tissue RNA - white matter [nTPM]":"1.8","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.9","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"1.4","Brain RNA - basal ganglia [nTPM]":"1.4","Brain RNA - cerebellum [nTPM]":"2.2","Brain RNA - cerebral cortex [nTPM]":"1.9","Brain RNA - hippocampal formation [nTPM]":"1.4","Brain RNA - hypothalamus [nTPM]":"2.0","Brain RNA - medulla oblongata [nTPM]":"1.6","Brain RNA - midbrain [nTPM]":"1.8","Brain RNA - pons [nTPM]":"2.0","Brain RNA - spinal cord [nTPM]":"2.1","Brain RNA - thalamus [nTPM]":"1.1","Brain RNA - white matter [nTPM]":"1.8","Single Cell Type RNA - Adipocytes [nTPM]":"9.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.4","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"5.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"8.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"3.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"4.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"5.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.2","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"6.8","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.4","Single Cell Type RNA - Muller glia cells [nTPM]":"32.0","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"1.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"3.9","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.4","Single Cell Type RNA - Urothelial cells [nTPM]":"7.9"},{"Gene":"SLC16A12","Gene synonym":["MCT12"],"Ensembl":"ENSG00000152779","Gene description":"Solute carrier family 16 member 12","Uniprot":["Q6ZSM3"],"Chromosome":"10","Position":"89430299-89556641","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Symport","Transport"],"Molecular function":null,"Disease involvement":["Cataract"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"choroid plexus":"92.2","epididymis":"51.8","kidney":"85.2","pancreas":"25.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Enteroendocrine cells":"18.1","Leydig cells":"27.1","Peritubular cells":"26.7","Proximal tubular cells":"69.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"10","RNA cancer specific FPKM":{"renal cancer":"18.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"ASC TERT1":"23.0","HSkMC":"8.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037587"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA037587":"AB_2732475"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.50e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-3"},"Tissue RNA - adipose tissue [nTPM]":"1.8","Tissue RNA - adrenal gland [nTPM]":"2.5","Tissue RNA - amygdala [nTPM]":"0.8","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"1.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.9","Tissue RNA - cerebellum [nTPM]":"1.0","Tissue RNA - cerebral cortex [nTPM]":"2.7","Tissue RNA - cervix [nTPM]":"9.2","Tissue RNA - choroid plexus [nTPM]":"92.2","Tissue RNA - colon [nTPM]":"0.8","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"1.4","Tissue RNA - epididymis [nTPM]":"51.8","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"4.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"4.9","Tissue RNA - hippocampal formation [nTPM]":"2.9","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"85.2","Tissue RNA - liver [nTPM]":"2.0","Tissue RNA - lung [nTPM]":"2.5","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"1.6","Tissue RNA - ovary [nTPM]":"1.3","Tissue RNA - pancreas [nTPM]":"25.3","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"3.4","Tissue RNA - placenta [nTPM]":"11.6","Tissue RNA - pons [nTPM]":"0.6","Tissue RNA - prostate [nTPM]":"0.6","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"14.1","Tissue RNA - skeletal muscle [nTPM]":"1.6","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"1.2","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"1.0","Tissue RNA - testis [nTPM]":"3.3","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"6.2","Tissue RNA - tongue [nTPM]":"2.5","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"3.0","Cell RNA - ASC TERT1 [nTPM]":"23.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"1.2","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"0.5","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"3.7","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"8.2","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.2","Cell RNA - hTERT-HME1 [nTPM]":"1.5","Cell RNA - hTERT-RPE1 [nTPM]":"2.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"1.3","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.8","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"2.8","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.9","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.8","Brain RNA - basal ganglia [nTPM]":"1.1","Brain RNA - cerebellum [nTPM]":"1.0","Brain RNA - cerebral cortex [nTPM]":"2.7","Brain RNA - hippocampal formation [nTPM]":"2.9","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"1.6","Brain RNA - pons [nTPM]":"0.6","Brain RNA - spinal cord [nTPM]":"1.2","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.9","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"2.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"8.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.8","Single Cell Type RNA - Endothelial cells [nTPM]":"1.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.1","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.1","Single Cell Type RNA - Fibroblasts [nTPM]":"2.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"2.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.2","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.9","Single Cell Type RNA - Late spermatids [nTPM]":"4.8","Single Cell Type RNA - Leydig cells [nTPM]":"27.1","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"26.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"69.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.0","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.8"},{"Gene":"SLC16A13","Gene synonym":["MCT13"],"Ensembl":"ENSG00000174327","Gene description":"Solute carrier family 16 member 13","Uniprot":["Q7RTY0"],"Chromosome":"17","Position":"7036015-7040117","Protein class":["Disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Symport","Transport"],"Molecular function":null,"Disease involvement":["Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"36.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"8.2","NK-cells":"6.2","Squamous epithelial cells":"7.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"22.8","GAMG":"26.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065245"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA065245":"AB_2685443"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.50e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.31e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.70e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.4","Tissue RNA - adrenal gland [nTPM]":"1.0","Tissue RNA - amygdala [nTPM]":"1.1","Tissue RNA - appendix [nTPM]":"2.1","Tissue RNA - basal ganglia [nTPM]":"0.8","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"1.4","Tissue RNA - cerebellum [nTPM]":"1.8","Tissue RNA - cerebral cortex [nTPM]":"1.1","Tissue RNA - cervix [nTPM]":"1.8","Tissue RNA - choroid plexus [nTPM]":"1.0","Tissue RNA - colon [nTPM]":"2.2","Tissue RNA - duodenum [nTPM]":"9.2","Tissue RNA - endometrium 1 [nTPM]":"0.8","Tissue RNA - epididymis [nTPM]":"1.3","Tissue RNA - esophagus [nTPM]":"5.3","Tissue RNA - fallopian tube [nTPM]":"1.8","Tissue RNA - gallbladder [nTPM]":"3.7","Tissue RNA - heart muscle [nTPM]":"1.6","Tissue RNA - hippocampal formation [nTPM]":"0.9","Tissue RNA - hypothalamus [nTPM]":"1.0","Tissue RNA - kidney [nTPM]":"6.8","Tissue RNA - liver [nTPM]":"36.1","Tissue RNA - lung [nTPM]":"2.4","Tissue RNA - lymph node [nTPM]":"2.8","Tissue RNA - medulla oblongata [nTPM]":"1.2","Tissue RNA - midbrain [nTPM]":"1.2","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"1.2","Tissue RNA - parathyroid gland [nTPM]":"2.9","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"1.5","Tissue RNA - pons [nTPM]":"1.0","Tissue RNA - prostate [nTPM]":"1.4","Tissue RNA - rectum [nTPM]":"1.6","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"3.3","Tissue RNA - seminal vesicle [nTPM]":"0.8","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"5.3","Tissue RNA - small intestine [nTPM]":"5.5","Tissue RNA - smooth muscle [nTPM]":"0.9","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"3.5","Tissue RNA - stomach 1 [nTPM]":"1.9","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"1.8","Tissue RNA - thyroid gland [nTPM]":"3.3","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"2.5","Tissue RNA - urinary bladder [nTPM]":"1.2","Tissue RNA - vagina [nTPM]":"2.6","Tissue RNA - white matter [nTPM]":"0.8","Cell RNA - A-431 [nTPM]":"13.1","Cell RNA - A549 [nTPM]":"22.8","Cell RNA - AF22 [nTPM]":"5.3","Cell RNA - AN3-CA [nTPM]":"3.2","Cell RNA - ASC diff [nTPM]":"3.2","Cell RNA - ASC TERT1 [nTPM]":"1.8","Cell RNA - BEWO [nTPM]":"2.2","Cell RNA - BJ [nTPM]":"1.3","Cell RNA - BJ hTERT+ [nTPM]":"3.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.5","Cell RNA - CACO-2 [nTPM]":"7.4","Cell RNA - CAPAN-2 [nTPM]":"14.3","Cell RNA - Daudi [nTPM]":"8.3","Cell RNA - EFO-21 [nTPM]":"2.2","Cell RNA - fHDF\/TERT166 [nTPM]":"2.1","Cell RNA - GAMG [nTPM]":"26.2","Cell RNA - HaCaT [nTPM]":"20.1","Cell RNA - HAP1 [nTPM]":"4.1","Cell RNA - HBEC3-KT [nTPM]":"7.0","Cell RNA - HBF TERT88 [nTPM]":"1.2","Cell RNA - HDLM-2 [nTPM]":"10.3","Cell RNA - HEK 293 [nTPM]":"2.9","Cell RNA - HEL [nTPM]":"3.4","Cell RNA - HeLa [nTPM]":"1.8","Cell RNA - Hep G2 [nTPM]":"18.0","Cell RNA - HHSteC [nTPM]":"3.6","Cell RNA - HL-60 [nTPM]":"1.2","Cell RNA - HMC-1 [nTPM]":"7.6","Cell RNA - HSkMC [nTPM]":"2.1","Cell RNA - hTCEpi [nTPM]":"7.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.3","Cell RNA - hTERT-HME1 [nTPM]":"3.5","Cell RNA - hTERT-RPE1 [nTPM]":"3.9","Cell RNA - HUVEC TERT2 [nTPM]":"11.9","Cell RNA - JURKAT [nTPM]":"7.4","Cell RNA - K-562 [nTPM]":"4.0","Cell RNA - Karpas-707 [nTPM]":"2.3","Cell RNA - LHCN-M2 [nTPM]":"3.1","Cell RNA - MCF7 [nTPM]":"6.5","Cell RNA - MOLT-4 [nTPM]":"5.1","Cell RNA - NB-4 [nTPM]":"2.1","Cell RNA - NTERA-2 [nTPM]":"2.2","Cell RNA - OE19 [nTPM]":"6.6","Cell RNA - PC-3 [nTPM]":"1.8","Cell RNA - REH [nTPM]":"2.4","Cell RNA - RH-30 [nTPM]":"1.8","Cell RNA - RPMI-8226 [nTPM]":"1.4","Cell RNA - RPTEC TERT1 [nTPM]":"2.7","Cell RNA - RT4 [nTPM]":"3.6","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"1.4","Cell RNA - SiHa [nTPM]":"4.0","Cell RNA - SK-BR-3 [nTPM]":"2.2","Cell RNA - SK-MEL-30 [nTPM]":"1.8","Cell RNA - SuSa [nTPM]":"7.8","Cell RNA - T-47d [nTPM]":"6.1","Cell RNA - THP-1 [nTPM]":"1.8","Cell RNA - TIME [nTPM]":"4.5","Cell RNA - U-138 MG [nTPM]":"1.8","Cell RNA - U-2 OS [nTPM]":"4.1","Cell RNA - U-2197 [nTPM]":"3.0","Cell RNA - U-251 MG [nTPM]":"1.9","Cell RNA - U-266\/70 [nTPM]":"4.0","Cell RNA - U-266\/84 [nTPM]":"8.9","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"5.4","Cell RNA - U-937 [nTPM]":"3.0","Cell RNA - WM-115 [nTPM]":"0.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.8","Blood RNA - eosinophil [nTPM]":"1.0","Blood RNA - gdT-cell [nTPM]":"1.2","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"0.9","Blood RNA - memory B-cell [nTPM]":"1.1","Blood RNA - memory CD4 T-cell [nTPM]":"1.0","Blood RNA - memory CD8 T-cell [nTPM]":"1.5","Blood RNA - myeloid DC [nTPM]":"0.8","Blood RNA - naive B-cell [nTPM]":"2.5","Blood RNA - naive CD4 T-cell [nTPM]":"1.1","Blood RNA - naive CD8 T-cell [nTPM]":"1.1","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"1.2","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"1.1","Brain RNA - basal ganglia [nTPM]":"0.8","Brain RNA - cerebellum [nTPM]":"1.8","Brain RNA - cerebral cortex [nTPM]":"1.1","Brain RNA - hippocampal formation [nTPM]":"0.9","Brain RNA - hypothalamus [nTPM]":"1.0","Brain RNA - medulla oblongata [nTPM]":"1.2","Brain RNA - midbrain [nTPM]":"1.2","Brain RNA - pons [nTPM]":"1.0","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"0.8","Single Cell Type RNA - Adipocytes [nTPM]":"2.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"5.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - dendritic cells [nTPM]":"2.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"2.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"1.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"8.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.5","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.2","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"3.1","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"1.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"1.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.9","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - T-cells [nTPM]":"4.7","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.0"},{"Gene":"SLC16A2","Gene synonym":["AHDS","DXS128","MCT7","MCT8","MRX22","XPCT"],"Ensembl":"ENSG00000147100","Gene description":"Solute carrier family 16 member 2","Uniprot":["P36021"],"Chromosome":"X","Position":"74421493-74533917","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"40.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"22.2","Hepatocytes":"63.7","Inhibitory neurons":"21.6","Oligodendrocyte precursor cells":"23.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ":"83.9","GAMG":"70.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072719"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA072719":"AB_2686552"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.88e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.83e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.16e-4"},"Tissue RNA - adipose tissue [nTPM]":"13.8","Tissue RNA - adrenal gland [nTPM]":"24.7","Tissue RNA - amygdala [nTPM]":"4.6","Tissue RNA - appendix [nTPM]":"4.8","Tissue RNA - basal ganglia [nTPM]":"5.8","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"5.4","Tissue RNA - cerebellum [nTPM]":"1.7","Tissue RNA - cerebral cortex [nTPM]":"5.7","Tissue RNA - cervix [nTPM]":"9.4","Tissue RNA - choroid plexus [nTPM]":"1.2","Tissue RNA - colon [nTPM]":"7.0","Tissue RNA - duodenum [nTPM]":"3.3","Tissue RNA - endometrium 1 [nTPM]":"10.3","Tissue RNA - epididymis [nTPM]":"1.7","Tissue RNA - esophagus [nTPM]":"2.9","Tissue RNA - fallopian tube [nTPM]":"9.3","Tissue RNA - gallbladder [nTPM]":"6.0","Tissue RNA - heart muscle [nTPM]":"10.4","Tissue RNA - hippocampal formation [nTPM]":"7.7","Tissue RNA - hypothalamus [nTPM]":"4.9","Tissue RNA - kidney [nTPM]":"7.9","Tissue RNA - liver [nTPM]":"40.7","Tissue RNA - lung [nTPM]":"7.5","Tissue RNA - lymph node [nTPM]":"0.9","Tissue RNA - medulla oblongata [nTPM]":"5.6","Tissue RNA - midbrain [nTPM]":"3.9","Tissue RNA - ovary [nTPM]":"12.8","Tissue RNA - pancreas [nTPM]":"5.5","Tissue RNA - parathyroid gland [nTPM]":"11.7","Tissue RNA - pituitary gland [nTPM]":"9.8","Tissue RNA - placenta [nTPM]":"9.2","Tissue RNA - pons [nTPM]":"1.8","Tissue RNA - prostate [nTPM]":"6.2","Tissue RNA - rectum [nTPM]":"1.8","Tissue RNA - retina [nTPM]":"1.1","Tissue RNA - salivary gland [nTPM]":"5.0","Tissue RNA - seminal vesicle [nTPM]":"5.8","Tissue RNA - skeletal muscle [nTPM]":"2.7","Tissue RNA - skin 1 [nTPM]":"2.5","Tissue RNA - small intestine [nTPM]":"3.1","Tissue RNA - smooth muscle [nTPM]":"6.9","Tissue RNA - spinal cord [nTPM]":"3.5","Tissue RNA - spleen [nTPM]":"1.2","Tissue RNA - stomach 1 [nTPM]":"4.7","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"8.1","Tissue RNA - thymus [nTPM]":"5.7","Tissue RNA - thyroid gland [nTPM]":"12.6","Tissue RNA - tongue [nTPM]":"3.7","Tissue RNA - tonsil [nTPM]":"1.8","Tissue RNA - urinary bladder [nTPM]":"6.6","Tissue RNA - vagina [nTPM]":"6.2","Tissue RNA - white matter [nTPM]":"3.0","Cell RNA - A-431 [nTPM]":"8.4","Cell RNA - A549 [nTPM]":"10.4","Cell RNA - AF22 [nTPM]":"7.2","Cell RNA - AN3-CA [nTPM]":"43.1","Cell RNA - ASC diff [nTPM]":"20.8","Cell RNA - ASC TERT1 [nTPM]":"11.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"83.9","Cell RNA - BJ hTERT+ [nTPM]":"29.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"38.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.6","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.9","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.3","Cell RNA - fHDF\/TERT166 [nTPM]":"37.5","Cell RNA - GAMG [nTPM]":"70.8","Cell RNA - HaCaT [nTPM]":"1.7","Cell RNA - HAP1 [nTPM]":"1.1","Cell RNA - HBEC3-KT [nTPM]":"40.2","Cell RNA - HBF TERT88 [nTPM]":"22.1","Cell RNA - HDLM-2 [nTPM]":"6.1","Cell RNA - HEK 293 [nTPM]":"3.6","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"1.5","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"16.5","Cell RNA - hTCEpi [nTPM]":"9.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.3","Cell RNA - hTERT-HME1 [nTPM]":"23.3","Cell RNA - hTERT-RPE1 [nTPM]":"14.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"9.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"2.7","Cell RNA - NTERA-2 [nTPM]":"27.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"7.8","Cell RNA - REH [nTPM]":"17.4","Cell RNA - RH-30 [nTPM]":"19.9","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"18.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"1.9","Cell RNA - SH-SY5Y [nTPM]":"12.0","Cell RNA - SiHa [nTPM]":"9.6","Cell RNA - SK-BR-3 [nTPM]":"50.2","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"2.5","Cell RNA - T-47d [nTPM]":"0.6","Cell RNA - THP-1 [nTPM]":"1.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"32.5","Cell RNA - U-2 OS [nTPM]":"8.8","Cell RNA - U-2197 [nTPM]":"35.7","Cell RNA - U-251 MG [nTPM]":"41.9","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"34.7","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.6","Brain RNA - basal ganglia [nTPM]":"5.8","Brain RNA - cerebellum [nTPM]":"1.7","Brain RNA - cerebral cortex [nTPM]":"5.7","Brain RNA - hippocampal formation [nTPM]":"7.7","Brain RNA - hypothalamus [nTPM]":"4.9","Brain RNA - medulla oblongata [nTPM]":"5.6","Brain RNA - midbrain [nTPM]":"3.9","Brain RNA - pons [nTPM]":"1.8","Brain RNA - spinal cord [nTPM]":"3.5","Brain RNA - thalamus [nTPM]":"8.1","Brain RNA - white matter [nTPM]":"3.0","Single Cell Type RNA - Adipocytes [nTPM]":"5.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"22.2","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"5.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"2.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.7","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.8","Single Cell Type RNA - Endothelial cells [nTPM]":"6.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.9","Single Cell Type RNA - Fibroblasts [nTPM]":"11.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"1.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"63.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"15.2","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"6.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"23.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"20.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.1","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"1.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"4.9"},{"Gene":"SLC17A5","Gene synonym":["AST","ISSD","NSD","SD","SIALIN","SIASD","SLD"],"Ensembl":"ENSG00000119899","Gene description":"Solute carrier family 17 member 5","Uniprot":["Q9NRA2"],"Chromosome":"6","Position":"73593379-73653992","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"parathyroid gland":"310.5"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"47.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"99.9","ASC TERT1":"74.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044479"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 27: Mucus-secreting cells - Mucin production","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA044479":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.52e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.4","Tissue RNA - adrenal gland [nTPM]":"10.5","Tissue RNA - amygdala [nTPM]":"5.9","Tissue RNA - appendix [nTPM]":"6.4","Tissue RNA - basal ganglia [nTPM]":"6.0","Tissue RNA - bone marrow [nTPM]":"6.8","Tissue RNA - breast [nTPM]":"13.8","Tissue RNA - cerebellum [nTPM]":"6.2","Tissue RNA - cerebral cortex [nTPM]":"7.0","Tissue RNA - cervix [nTPM]":"10.7","Tissue RNA - choroid plexus [nTPM]":"5.9","Tissue RNA - colon [nTPM]":"20.4","Tissue RNA - duodenum [nTPM]":"16.4","Tissue RNA - endometrium 1 [nTPM]":"9.4","Tissue RNA - epididymis [nTPM]":"44.6","Tissue RNA - esophagus [nTPM]":"8.4","Tissue RNA - fallopian tube [nTPM]":"5.3","Tissue RNA - gallbladder [nTPM]":"10.4","Tissue RNA - heart muscle [nTPM]":"8.5","Tissue RNA - hippocampal formation [nTPM]":"6.5","Tissue RNA - hypothalamus [nTPM]":"8.5","Tissue RNA - kidney [nTPM]":"31.9","Tissue RNA - liver [nTPM]":"17.6","Tissue RNA - lung [nTPM]":"13.2","Tissue RNA - lymph node [nTPM]":"5.3","Tissue RNA - medulla oblongata [nTPM]":"6.5","Tissue RNA - midbrain [nTPM]":"7.0","Tissue RNA - ovary [nTPM]":"4.0","Tissue RNA - pancreas [nTPM]":"11.6","Tissue RNA - parathyroid gland [nTPM]":"310.5","Tissue RNA - pituitary gland [nTPM]":"9.9","Tissue RNA - placenta [nTPM]":"21.7","Tissue RNA - pons [nTPM]":"7.8","Tissue RNA - prostate [nTPM]":"16.8","Tissue RNA - rectum [nTPM]":"22.1","Tissue RNA - retina [nTPM]":"18.3","Tissue RNA - salivary gland [nTPM]":"30.3","Tissue RNA - seminal vesicle [nTPM]":"14.7","Tissue RNA - skeletal muscle [nTPM]":"5.4","Tissue RNA - skin 1 [nTPM]":"7.1","Tissue RNA - small intestine [nTPM]":"21.1","Tissue RNA - smooth muscle [nTPM]":"10.6","Tissue RNA - spinal cord [nTPM]":"5.7","Tissue RNA - spleen [nTPM]":"7.0","Tissue RNA - stomach 1 [nTPM]":"14.4","Tissue RNA - testis [nTPM]":"6.1","Tissue RNA - thalamus [nTPM]":"7.1","Tissue RNA - thymus [nTPM]":"4.5","Tissue RNA - thyroid gland [nTPM]":"43.5","Tissue RNA - tongue [nTPM]":"6.2","Tissue RNA - tonsil [nTPM]":"5.6","Tissue RNA - urinary bladder [nTPM]":"12.6","Tissue RNA - vagina [nTPM]":"6.3","Tissue RNA - white matter [nTPM]":"7.6","Cell RNA - A-431 [nTPM]":"7.4","Cell RNA - A549 [nTPM]":"9.9","Cell RNA - AF22 [nTPM]":"9.7","Cell RNA - AN3-CA [nTPM]":"15.6","Cell RNA - ASC diff [nTPM]":"99.9","Cell RNA - ASC TERT1 [nTPM]":"74.2","Cell RNA - BEWO [nTPM]":"12.8","Cell RNA - BJ [nTPM]":"23.8","Cell RNA - BJ hTERT+ [nTPM]":"59.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"22.0","Cell RNA - CACO-2 [nTPM]":"6.6","Cell RNA - CAPAN-2 [nTPM]":"17.6","Cell RNA - Daudi [nTPM]":"6.8","Cell RNA - EFO-21 [nTPM]":"11.2","Cell RNA - fHDF\/TERT166 [nTPM]":"32.9","Cell RNA - GAMG [nTPM]":"14.8","Cell RNA - HaCaT [nTPM]":"12.6","Cell RNA - HAP1 [nTPM]":"13.7","Cell RNA - HBEC3-KT [nTPM]":"5.9","Cell RNA - HBF TERT88 [nTPM]":"11.2","Cell RNA - HDLM-2 [nTPM]":"4.8","Cell RNA - HEK 293 [nTPM]":"15.5","Cell RNA - HEL [nTPM]":"2.8","Cell RNA - HeLa [nTPM]":"5.1","Cell RNA - Hep G2 [nTPM]":"15.4","Cell RNA - HHSteC [nTPM]":"19.4","Cell RNA - HL-60 [nTPM]":"5.6","Cell RNA - HMC-1 [nTPM]":"10.8","Cell RNA - HSkMC [nTPM]":"34.2","Cell RNA - hTCEpi [nTPM]":"8.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.2","Cell RNA - hTERT-HME1 [nTPM]":"9.7","Cell RNA - hTERT-RPE1 [nTPM]":"26.4","Cell RNA - HUVEC TERT2 [nTPM]":"16.2","Cell RNA - JURKAT [nTPM]":"9.0","Cell RNA - K-562 [nTPM]":"7.1","Cell RNA - Karpas-707 [nTPM]":"7.2","Cell RNA - LHCN-M2 [nTPM]":"22.3","Cell RNA - MCF7 [nTPM]":"4.9","Cell RNA - MOLT-4 [nTPM]":"2.3","Cell RNA - NB-4 [nTPM]":"3.3","Cell RNA - NTERA-2 [nTPM]":"7.1","Cell RNA - OE19 [nTPM]":"30.9","Cell RNA - PC-3 [nTPM]":"5.7","Cell RNA - REH [nTPM]":"5.0","Cell RNA - RH-30 [nTPM]":"12.1","Cell RNA - RPMI-8226 [nTPM]":"28.5","Cell RNA - RPTEC TERT1 [nTPM]":"16.0","Cell RNA - RT4 [nTPM]":"20.2","Cell RNA - SCLC-21H [nTPM]":"3.8","Cell RNA - SH-SY5Y [nTPM]":"6.7","Cell RNA - SiHa [nTPM]":"4.8","Cell RNA - SK-BR-3 [nTPM]":"14.0","Cell RNA - SK-MEL-30 [nTPM]":"14.4","Cell RNA - SuSa [nTPM]":"14.0","Cell RNA - T-47d [nTPM]":"6.3","Cell RNA - THP-1 [nTPM]":"34.1","Cell RNA - TIME [nTPM]":"23.5","Cell RNA - U-138 MG [nTPM]":"3.0","Cell RNA - U-2 OS [nTPM]":"2.8","Cell RNA - U-2197 [nTPM]":"12.1","Cell RNA - U-251 MG [nTPM]":"5.7","Cell RNA - U-266\/70 [nTPM]":"20.4","Cell RNA - U-266\/84 [nTPM]":"30.6","Cell RNA - U-698 [nTPM]":"1.9","Cell RNA - U-87 MG [nTPM]":"10.5","Cell RNA - U-937 [nTPM]":"11.6","Cell RNA - WM-115 [nTPM]":"9.0","Blood RNA - basophil [nTPM]":"13.3","Blood RNA - classical monocyte [nTPM]":"7.9","Blood RNA - eosinophil [nTPM]":"3.3","Blood RNA - gdT-cell [nTPM]":"6.0","Blood RNA - intermediate monocyte [nTPM]":"7.4","Blood RNA - MAIT T-cell [nTPM]":"5.8","Blood RNA - memory B-cell [nTPM]":"3.9","Blood RNA - memory CD4 T-cell [nTPM]":"6.6","Blood RNA - memory CD8 T-cell [nTPM]":"5.8","Blood RNA - myeloid DC [nTPM]":"7.6","Blood RNA - naive B-cell [nTPM]":"2.4","Blood RNA - naive CD4 T-cell [nTPM]":"5.4","Blood RNA - naive CD8 T-cell [nTPM]":"6.0","Blood RNA - neutrophil [nTPM]":"5.7","Blood RNA - NK-cell [nTPM]":"8.9","Blood RNA - non-classical monocyte [nTPM]":"4.8","Blood RNA - plasmacytoid DC [nTPM]":"5.5","Blood RNA - T-reg [nTPM]":"6.6","Blood RNA - total PBMC [nTPM]":"4.9","Brain RNA - amygdala [nTPM]":"5.9","Brain RNA - basal ganglia [nTPM]":"6.0","Brain RNA - cerebellum [nTPM]":"6.2","Brain RNA - cerebral cortex [nTPM]":"7.0","Brain RNA - hippocampal formation [nTPM]":"6.5","Brain RNA - hypothalamus [nTPM]":"8.5","Brain RNA - medulla oblongata [nTPM]":"6.5","Brain RNA - midbrain [nTPM]":"7.0","Brain RNA - pons [nTPM]":"7.8","Brain RNA - spinal cord [nTPM]":"5.7","Brain RNA - thalamus [nTPM]":"7.1","Brain RNA - white matter [nTPM]":"7.6","Single Cell Type RNA - Adipocytes [nTPM]":"8.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.7","Single Cell Type RNA - Astrocytes [nTPM]":"16.3","Single Cell Type RNA - B-cells [nTPM]":"8.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"8.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"17.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"51.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.4","Single Cell Type RNA - dendritic cells [nTPM]":"11.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"46.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"14.2","Single Cell Type RNA - Early spermatids [nTPM]":"36.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.8","Single Cell Type RNA - Endothelial cells [nTPM]":"13.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.1","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"47.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.5","Single Cell Type RNA - Fibroblasts [nTPM]":"25.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.6","Single Cell Type RNA - granulocytes [nTPM]":"14.5","Single Cell Type RNA - Granulosa cells [nTPM]":"3.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.9","Single Cell Type RNA - Hepatocytes [nTPM]":"32.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"64.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"46.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"47.7","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"24.8","Single Cell Type RNA - Langerhans cells [nTPM]":"22.7","Single Cell Type RNA - Late spermatids [nTPM]":"48.3","Single Cell Type RNA - Leydig cells [nTPM]":"7.5","Single Cell Type RNA - Macrophages [nTPM]":"25.4","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"11.2","Single Cell Type RNA - Muller glia cells [nTPM]":"8.3","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.2","Single Cell Type RNA - Paneth cells [nTPM]":"17.5","Single Cell Type RNA - Peritubular cells [nTPM]":"11.3","Single Cell Type RNA - Plasma cells [nTPM]":"20.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"29.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"36.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"28.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.1","Single Cell Type RNA - Spermatocytes [nTPM]":"8.4","Single Cell Type RNA - Spermatogonia [nTPM]":"3.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.8","Single Cell Type RNA - T-cells [nTPM]":"11.0","Single Cell Type RNA - Theca cells [nTPM]":"2.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.2","Single Cell Type RNA - Urothelial cells [nTPM]":"30.7"},{"Gene":"SLC17A8","Gene synonym":["DFNA25","VGLUT3"],"Ensembl":"ENSG00000179520","Gene description":"Solute carrier family 17 member 8","Uniprot":["Q8NDX2"],"Chromosome":"12","Position":"100357074-100422055","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Hearing","Ion transport","Neurotransmitter transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"11.3","intestine":"5.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Endometrial ciliated cells":"13.3","Proximal enterocytes":"43.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"0.5"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"basal ganglia":"11.3","midbrain":"8.3","pons":"6.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB079058"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB079058":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-3"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"11.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"1.6","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"1.3","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.5","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"8.3","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"6.5","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"1.2","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"5.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"1.6","Tissue RNA - thymus [nTPM]":"1.4","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"11.3","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"1.6","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"1.3","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"8.3","Brain RNA - pons [nTPM]":"6.5","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"1.6","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.9","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.2","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"1.7","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"43.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SLC17A9","Gene synonym":["C20orf59","FLJ23412","VNUT"],"Ensembl":"ENSG00000101194","Gene description":"Solute carrier family 17 member 9","Uniprot":["Q9BYT1"],"Chromosome":"20","Position":"62952707-62969585","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Exocytosis","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"43.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"18.2","Gastric mucus-secreting cells":"29.0","Hepatocytes":"48.8","Hofbauer cells":"18.0","Intestinal goblet cells":"19.7","Plasma cells":"38.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"4.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ":"35.7","CACO-2":"32.9","Hep G2":"69.5","NB-4":"39.0","RPMI-8226":"36.1","U-937":"43.8"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047470"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA047470":"AB_2680060"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.78e-15"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.3","Tissue RNA - adrenal gland [nTPM]":"1.0","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"5.8","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"11.4","Tissue RNA - breast [nTPM]":"1.3","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"0.7","Tissue RNA - cervix [nTPM]":"1.9","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"3.7","Tissue RNA - duodenum [nTPM]":"5.5","Tissue RNA - endometrium 1 [nTPM]":"1.5","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.8","Tissue RNA - fallopian tube [nTPM]":"1.9","Tissue RNA - gallbladder [nTPM]":"1.3","Tissue RNA - heart muscle [nTPM]":"1.3","Tissue RNA - hippocampal formation [nTPM]":"0.6","Tissue RNA - hypothalamus [nTPM]":"0.8","Tissue RNA - kidney [nTPM]":"0.9","Tissue RNA - liver [nTPM]":"43.0","Tissue RNA - lung [nTPM]":"3.5","Tissue RNA - lymph node [nTPM]":"5.2","Tissue RNA - medulla oblongata [nTPM]":"1.2","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"1.7","Tissue RNA - pancreas [nTPM]":"1.4","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"2.2","Tissue RNA - placenta [nTPM]":"1.7","Tissue RNA - pons [nTPM]":"1.3","Tissue RNA - prostate [nTPM]":"1.3","Tissue RNA - rectum [nTPM]":"3.1","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"4.0","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"1.0","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"4.2","Tissue RNA - smooth muscle [nTPM]":"1.4","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"11.1","Tissue RNA - stomach 1 [nTPM]":"9.5","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"0.7","Tissue RNA - thyroid gland [nTPM]":"1.2","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"4.2","Tissue RNA - urinary bladder [nTPM]":"2.7","Tissue RNA - vagina [nTPM]":"1.7","Tissue RNA - white matter [nTPM]":"2.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.3","Cell RNA - ASC TERT1 [nTPM]":"3.1","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"35.7","Cell RNA - BJ hTERT+ [nTPM]":"10.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"18.0","Cell RNA - CACO-2 [nTPM]":"32.9","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"25.9","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"28.3","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"5.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"2.8","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"11.5","Cell RNA - HeLa [nTPM]":"0.9","Cell RNA - Hep G2 [nTPM]":"69.5","Cell RNA - HHSteC [nTPM]":"7.7","Cell RNA - HL-60 [nTPM]":"20.9","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"2.5","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.6","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"7.6","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"14.6","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.9","Cell RNA - NB-4 [nTPM]":"39.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"12.9","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"26.9","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"36.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"19.4","Cell RNA - TIME [nTPM]":"2.6","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"1.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"5.0","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"14.2","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"43.8","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.9","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"1.7","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"2.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"2.6","Blood RNA - naive B-cell [nTPM]":"1.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"4.9","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"0.7","Brain RNA - hippocampal formation [nTPM]":"0.6","Brain RNA - hypothalamus [nTPM]":"0.8","Brain RNA - medulla oblongata [nTPM]":"1.2","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"1.3","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"2.0","Single Cell Type RNA - Adipocytes [nTPM]":"1.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"18.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"1.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"5.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.3","Single Cell Type RNA - Endothelial cells [nTPM]":"1.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.9","Single Cell Type RNA - Fibroblasts [nTPM]":"4.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"29.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.5","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"2.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"48.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"5.1","Single Cell Type RNA - Langerhans cells [nTPM]":"12.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"7.2","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"1.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.7","Single Cell Type RNA - Paneth cells [nTPM]":"3.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"38.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"3.6","Single Cell Type RNA - Theca cells [nTPM]":"3.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"SLC18A3","Gene synonym":["VACHT"],"Ensembl":"ENSG00000187714","Gene description":"Solute carrier family 18 member A3","Uniprot":["Q16572"],"Chromosome":"10","Position":"49610310-49612720","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Neurotransmitter transport","Transport"],"Molecular function":null,"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"21","RNA tissue specific nTPM":{"brain":"25.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Fibroblasts":"7.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"SH-SY5Y":"7.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"spinal cord":"78.1"},"Antibody":["CAB079011"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB079011":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.7","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"2.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"19.7","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.1","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"4.9","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"18.9","Tissue RNA - midbrain [nTPM]":"8.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.2","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"25.6","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"3.6","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.7","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.7","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"6.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.8","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.7","Cell RNA - SH-SY5Y [nTPM]":"7.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.5","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.7","Brain RNA - basal ganglia [nTPM]":"2.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"19.7","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"4.9","Brain RNA - medulla oblongata [nTPM]":"18.9","Brain RNA - midbrain [nTPM]":"8.0","Brain RNA - pons [nTPM]":"25.6","Brain RNA - spinal cord [nTPM]":"3.6","Brain RNA - thalamus [nTPM]":"0.7","Brain RNA - white matter [nTPM]":"6.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"7.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SLC19A2","Gene synonym":["THTR1","TRMA"],"Ensembl":"ENSG00000117479","Gene description":"Solute carrier family 19 member 2","Uniprot":["O60779"],"Chromosome":"1","Position":"169463909-169485944","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Deafness","Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"124.1","tongue":"84.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Skeletal myocytes":"84.5","Syncytiotrophoblasts":"156.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006119","HPA016599"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA006119":"AB_1079996","HPA016599":"AB_1857005"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.41e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.90e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.70e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Tissue RNA - adipose tissue [nTPM]":"42.2","Tissue RNA - adrenal gland [nTPM]":"17.8","Tissue RNA - amygdala [nTPM]":"3.0","Tissue RNA - appendix [nTPM]":"8.3","Tissue RNA - basal ganglia [nTPM]":"3.1","Tissue RNA - bone marrow [nTPM]":"8.7","Tissue RNA - breast [nTPM]":"20.9","Tissue RNA - cerebellum [nTPM]":"5.1","Tissue RNA - cerebral cortex [nTPM]":"4.2","Tissue RNA - cervix [nTPM]":"10.5","Tissue RNA - choroid plexus [nTPM]":"9.3","Tissue RNA - colon [nTPM]":"11.8","Tissue RNA - duodenum [nTPM]":"3.5","Tissue RNA - endometrium 1 [nTPM]":"8.6","Tissue RNA - epididymis [nTPM]":"6.1","Tissue RNA - esophagus [nTPM]":"11.3","Tissue RNA - fallopian tube [nTPM]":"21.3","Tissue RNA - gallbladder [nTPM]":"25.8","Tissue RNA - heart muscle [nTPM]":"31.2","Tissue RNA - hippocampal formation [nTPM]":"4.0","Tissue RNA - hypothalamus [nTPM]":"3.6","Tissue RNA - kidney [nTPM]":"13.0","Tissue RNA - liver [nTPM]":"37.1","Tissue RNA - lung [nTPM]":"19.5","Tissue RNA - lymph node [nTPM]":"2.6","Tissue RNA - medulla oblongata [nTPM]":"4.9","Tissue RNA - midbrain [nTPM]":"3.7","Tissue RNA - ovary [nTPM]":"20.5","Tissue RNA - pancreas [nTPM]":"22.2","Tissue RNA - parathyroid gland [nTPM]":"24.8","Tissue RNA - pituitary gland [nTPM]":"19.0","Tissue RNA - placenta [nTPM]":"18.1","Tissue RNA - pons [nTPM]":"4.0","Tissue RNA - prostate [nTPM]":"10.5","Tissue RNA - rectum [nTPM]":"4.3","Tissue RNA - retina [nTPM]":"7.5","Tissue RNA - salivary gland [nTPM]":"12.5","Tissue RNA - seminal vesicle [nTPM]":"3.8","Tissue RNA - skeletal muscle [nTPM]":"124.1","Tissue RNA - skin 1 [nTPM]":"16.5","Tissue RNA - small intestine [nTPM]":"11.4","Tissue RNA - smooth muscle [nTPM]":"6.1","Tissue RNA - spinal cord [nTPM]":"3.7","Tissue RNA - spleen [nTPM]":"2.8","Tissue RNA - stomach 1 [nTPM]":"19.2","Tissue RNA - testis [nTPM]":"7.8","Tissue RNA - thalamus [nTPM]":"4.2","Tissue RNA - thymus [nTPM]":"4.1","Tissue RNA - thyroid gland [nTPM]":"15.7","Tissue RNA - tongue [nTPM]":"84.9","Tissue RNA - tonsil [nTPM]":"2.8","Tissue RNA - urinary bladder [nTPM]":"18.1","Tissue RNA - vagina [nTPM]":"12.9","Tissue RNA - white matter [nTPM]":"3.5","Cell RNA - A-431 [nTPM]":"7.4","Cell RNA - A549 [nTPM]":"5.1","Cell RNA - AF22 [nTPM]":"11.4","Cell RNA - AN3-CA [nTPM]":"9.0","Cell RNA - ASC diff [nTPM]":"34.4","Cell RNA - ASC TERT1 [nTPM]":"12.7","Cell RNA - BEWO [nTPM]":"25.0","Cell RNA - BJ [nTPM]":"5.8","Cell RNA - BJ hTERT+ [nTPM]":"4.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.5","Cell RNA - CACO-2 [nTPM]":"20.9","Cell RNA - CAPAN-2 [nTPM]":"7.6","Cell RNA - Daudi [nTPM]":"6.5","Cell RNA - EFO-21 [nTPM]":"6.4","Cell RNA - fHDF\/TERT166 [nTPM]":"3.9","Cell RNA - GAMG [nTPM]":"8.5","Cell RNA - HaCaT [nTPM]":"7.7","Cell RNA - HAP1 [nTPM]":"13.9","Cell RNA - HBEC3-KT [nTPM]":"8.5","Cell RNA - HBF TERT88 [nTPM]":"5.1","Cell RNA - HDLM-2 [nTPM]":"18.8","Cell RNA - HEK 293 [nTPM]":"13.0","Cell RNA - HEL [nTPM]":"6.2","Cell RNA - HeLa [nTPM]":"16.7","Cell RNA - Hep G2 [nTPM]":"19.3","Cell RNA - HHSteC [nTPM]":"18.7","Cell RNA - HL-60 [nTPM]":"15.8","Cell RNA - HMC-1 [nTPM]":"5.9","Cell RNA - HSkMC [nTPM]":"15.0","Cell RNA - hTCEpi [nTPM]":"12.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.4","Cell RNA - hTERT-HME1 [nTPM]":"18.8","Cell RNA - hTERT-RPE1 [nTPM]":"6.4","Cell RNA - HUVEC TERT2 [nTPM]":"7.0","Cell RNA - JURKAT [nTPM]":"11.3","Cell RNA - K-562 [nTPM]":"25.3","Cell RNA - Karpas-707 [nTPM]":"4.1","Cell RNA - LHCN-M2 [nTPM]":"7.9","Cell RNA - MCF7 [nTPM]":"5.0","Cell RNA - MOLT-4 [nTPM]":"8.2","Cell RNA - NB-4 [nTPM]":"7.1","Cell RNA - NTERA-2 [nTPM]":"25.8","Cell RNA - OE19 [nTPM]":"14.1","Cell RNA - PC-3 [nTPM]":"7.7","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"24.6","Cell RNA - RPMI-8226 [nTPM]":"7.5","Cell RNA - RPTEC TERT1 [nTPM]":"12.2","Cell RNA - RT4 [nTPM]":"15.5","Cell RNA - SCLC-21H [nTPM]":"9.9","Cell RNA - SH-SY5Y [nTPM]":"13.3","Cell RNA - SiHa [nTPM]":"8.0","Cell RNA - SK-BR-3 [nTPM]":"13.6","Cell RNA - SK-MEL-30 [nTPM]":"29.2","Cell RNA - SuSa [nTPM]":"12.8","Cell RNA - T-47d [nTPM]":"8.5","Cell RNA - THP-1 [nTPM]":"10.1","Cell RNA - TIME [nTPM]":"5.8","Cell RNA - U-138 MG [nTPM]":"5.5","Cell RNA - U-2 OS [nTPM]":"7.7","Cell RNA - U-2197 [nTPM]":"6.9","Cell RNA - U-251 MG [nTPM]":"11.4","Cell RNA - U-266\/70 [nTPM]":"5.6","Cell RNA - U-266\/84 [nTPM]":"5.6","Cell RNA - U-698 [nTPM]":"2.1","Cell RNA - U-87 MG [nTPM]":"8.1","Cell RNA - U-937 [nTPM]":"6.0","Cell RNA - WM-115 [nTPM]":"7.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"1.1","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"1.1","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.0","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.9","Blood RNA - non-classical monocyte [nTPM]":"2.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"3.0","Brain RNA - basal ganglia [nTPM]":"3.1","Brain RNA - cerebellum [nTPM]":"5.1","Brain RNA - cerebral cortex [nTPM]":"4.2","Brain RNA - hippocampal formation [nTPM]":"4.0","Brain RNA - hypothalamus [nTPM]":"3.6","Brain RNA - medulla oblongata [nTPM]":"4.9","Brain RNA - midbrain [nTPM]":"3.7","Brain RNA - pons [nTPM]":"4.0","Brain RNA - spinal cord [nTPM]":"3.7","Brain RNA - thalamus [nTPM]":"4.2","Brain RNA - white matter [nTPM]":"3.5","Single Cell Type RNA - Adipocytes [nTPM]":"13.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.3","Single Cell Type RNA - Astrocytes [nTPM]":"11.8","Single Cell Type RNA - B-cells [nTPM]":"7.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"29.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"43.9","Single Cell Type RNA - Bipolar cells [nTPM]":"5.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"34.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"27.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"11.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"26.9","Single Cell Type RNA - dendritic cells [nTPM]":"11.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"7.4","Single Cell Type RNA - Early spermatids [nTPM]":"4.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.7","Single Cell Type RNA - Endothelial cells [nTPM]":"3.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.5","Single Cell Type RNA - Fibroblasts [nTPM]":"52.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"49.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"42.7","Single Cell Type RNA - granulocytes [nTPM]":"10.2","Single Cell Type RNA - Granulosa cells [nTPM]":"4.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"29.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.0","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.4","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"2.9","Single Cell Type RNA - Langerhans cells [nTPM]":"8.8","Single Cell Type RNA - Late spermatids [nTPM]":"2.7","Single Cell Type RNA - Leydig cells [nTPM]":"6.8","Single Cell Type RNA - Macrophages [nTPM]":"18.3","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.5","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.6","Single Cell Type RNA - Paneth cells [nTPM]":"5.4","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"14.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"84.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.2","Single Cell Type RNA - Spermatocytes [nTPM]":"6.7","Single Cell Type RNA - Spermatogonia [nTPM]":"4.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"35.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"50.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"156.4","Single Cell Type RNA - T-cells [nTPM]":"7.5","Single Cell Type RNA - Theca cells [nTPM]":"3.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.7","Single Cell Type RNA - Urothelial cells [nTPM]":"28.9"},{"Gene":"SLC19A3","Gene synonym":["THTR2"],"Ensembl":"ENSG00000135917","Gene description":"Solute carrier family 19 member 3","Uniprot":["Q9BZV2"],"Chromosome":"2","Position":"227683763-227718028","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"46.7","breast":"28.4","placenta":"24.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cytotrophoblasts":"65.4","Syncytiotrophoblasts":"160.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"6.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"13.9","BEWO":"6.2","CACO-2":"20.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038898"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Plasma membrane","Cytosol"],"Antibody RRID":{"HPA038898":"AB_10673481"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-3"},"Tissue RNA - adipose tissue [nTPM]":"46.7","Tissue RNA - adrenal gland [nTPM]":"0.6","Tissue RNA - amygdala [nTPM]":"5.0","Tissue RNA - appendix [nTPM]":"1.9","Tissue RNA - basal ganglia [nTPM]":"3.3","Tissue RNA - bone marrow [nTPM]":"1.2","Tissue RNA - breast [nTPM]":"28.4","Tissue RNA - cerebellum [nTPM]":"4.7","Tissue RNA - cerebral cortex [nTPM]":"4.3","Tissue RNA - cervix [nTPM]":"0.5","Tissue RNA - choroid plexus [nTPM]":"1.0","Tissue RNA - colon [nTPM]":"2.6","Tissue RNA - duodenum [nTPM]":"9.1","Tissue RNA - endometrium 1 [nTPM]":"0.5","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.7","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"5.7","Tissue RNA - heart muscle [nTPM]":"0.7","Tissue RNA - hippocampal formation [nTPM]":"3.4","Tissue RNA - hypothalamus [nTPM]":"4.4","Tissue RNA - kidney [nTPM]":"2.2","Tissue RNA - liver [nTPM]":"13.8","Tissue RNA - lung [nTPM]":"4.1","Tissue RNA - lymph node [nTPM]":"0.8","Tissue RNA - medulla oblongata [nTPM]":"5.2","Tissue RNA - midbrain [nTPM]":"4.2","Tissue RNA - ovary [nTPM]":"0.9","Tissue RNA - pancreas [nTPM]":"1.7","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"24.1","Tissue RNA - pons [nTPM]":"5.4","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"1.8","Tissue RNA - retina [nTPM]":"2.2","Tissue RNA - salivary gland [nTPM]":"1.1","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.9","Tissue RNA - skin 1 [nTPM]":"1.6","Tissue RNA - small intestine [nTPM]":"5.6","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"4.4","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"5.7","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"0.8","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"1.0","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"4.0","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.9","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.8","Cell RNA - ASC diff [nTPM]":"13.9","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"6.2","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.6","Cell RNA - CACO-2 [nTPM]":"20.2","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"4.6","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"0.6","Cell RNA - HBEC3-KT [nTPM]":"0.5","Cell RNA - HBF TERT88 [nTPM]":"0.8","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"1.1","Cell RNA - Hep G2 [nTPM]":"0.8","Cell RNA - HHSteC [nTPM]":"1.8","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"3.4","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.8","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.6","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.6","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"3.0","Cell RNA - OE19 [nTPM]":"0.7","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.9","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"1.9","Cell RNA - SK-MEL-30 [nTPM]":"0.5","Cell RNA - SuSa [nTPM]":"2.6","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.6","Cell RNA - U-138 MG [nTPM]":"0.4","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"4.1","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.6","Cell RNA - U-87 MG [nTPM]":"1.4","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"6.8","Blood RNA - classical monocyte [nTPM]":"0.8","Blood RNA - eosinophil [nTPM]":"1.0","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"1.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"3.3","Blood RNA - NK-cell [nTPM]":"2.2","Blood RNA - non-classical monocyte [nTPM]":"0.7","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"5.0","Brain RNA - basal ganglia [nTPM]":"3.3","Brain RNA - cerebellum [nTPM]":"4.7","Brain RNA - cerebral cortex [nTPM]":"4.3","Brain RNA - hippocampal formation [nTPM]":"3.4","Brain RNA - hypothalamus [nTPM]":"4.4","Brain RNA - medulla oblongata [nTPM]":"5.2","Brain RNA - midbrain [nTPM]":"4.2","Brain RNA - pons [nTPM]":"5.4","Brain RNA - spinal cord [nTPM]":"4.4","Brain RNA - thalamus [nTPM]":"5.7","Brain RNA - white matter [nTPM]":"4.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.1","Single Cell Type RNA - Astrocytes [nTPM]":"2.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"5.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"65.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"2.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.4","Single Cell Type RNA - Fibroblasts [nTPM]":"3.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"13.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"25.3","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"1.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"160.6","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"SLC1A1","Gene synonym":["EAAC1","EAAT3"],"Ensembl":"ENSG00000106688","Gene description":"Solute carrier family 1 member 1","Uniprot":["P43005"],"Chromosome":"9","Position":"4490468-4587469","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Schizophrenia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"45.0","intestine":"64.7","kidney":"51.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"163.5","Glandular and luminal cells":"98.7","Hepatocytes":"68.4","Microglial cells":"67.5","Oligodendrocyte precursor cells":"161.4","Proximal enterocytes":"110.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC TERT1":"29.1","HDLM-2":"70.9","HUVEC TERT2":"32.5","RPTEC TERT1":"66.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062356"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA062356":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.83e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.86e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Tissue RNA - adipose tissue [nTPM]":"4.6","Tissue RNA - adrenal gland [nTPM]":"1.7","Tissue RNA - amygdala [nTPM]":"13.2","Tissue RNA - appendix [nTPM]":"2.3","Tissue RNA - basal ganglia [nTPM]":"15.4","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"4.1","Tissue RNA - cerebellum [nTPM]":"9.5","Tissue RNA - cerebral cortex [nTPM]":"14.8","Tissue RNA - cervix [nTPM]":"5.8","Tissue RNA - choroid plexus [nTPM]":"12.9","Tissue RNA - colon [nTPM]":"12.4","Tissue RNA - duodenum [nTPM]":"34.8","Tissue RNA - endometrium 1 [nTPM]":"3.7","Tissue RNA - epididymis [nTPM]":"45.0","Tissue RNA - esophagus [nTPM]":"2.3","Tissue RNA - fallopian tube [nTPM]":"2.6","Tissue RNA - gallbladder [nTPM]":"25.5","Tissue RNA - heart muscle [nTPM]":"2.8","Tissue RNA - hippocampal formation [nTPM]":"16.5","Tissue RNA - hypothalamus [nTPM]":"12.6","Tissue RNA - kidney [nTPM]":"51.0","Tissue RNA - liver [nTPM]":"41.2","Tissue RNA - lung [nTPM]":"20.9","Tissue RNA - lymph node [nTPM]":"2.6","Tissue RNA - medulla oblongata [nTPM]":"10.8","Tissue RNA - midbrain [nTPM]":"13.0","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"2.1","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"6.8","Tissue RNA - placenta [nTPM]":"8.1","Tissue RNA - pons [nTPM]":"13.6","Tissue RNA - prostate [nTPM]":"6.3","Tissue RNA - rectum [nTPM]":"10.2","Tissue RNA - retina [nTPM]":"6.0","Tissue RNA - salivary gland [nTPM]":"4.8","Tissue RNA - seminal vesicle [nTPM]":"3.2","Tissue RNA - skeletal muscle [nTPM]":"1.4","Tissue RNA - skin 1 [nTPM]":"1.5","Tissue RNA - small intestine [nTPM]":"64.7","Tissue RNA - smooth muscle [nTPM]":"3.2","Tissue RNA - spinal cord [nTPM]":"10.9","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"5.2","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"13.9","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"29.5","Tissue RNA - tongue [nTPM]":"1.3","Tissue RNA - tonsil [nTPM]":"8.2","Tissue RNA - urinary bladder [nTPM]":"5.6","Tissue RNA - vagina [nTPM]":"1.5","Tissue RNA - white matter [nTPM]":"10.1","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"2.0","Cell RNA - AF22 [nTPM]":"1.6","Cell RNA - AN3-CA [nTPM]":"9.5","Cell RNA - ASC diff [nTPM]":"24.3","Cell RNA - ASC TERT1 [nTPM]":"29.1","Cell RNA - BEWO [nTPM]":"8.3","Cell RNA - BJ [nTPM]":"10.4","Cell RNA - BJ hTERT+ [nTPM]":"21.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.1","Cell RNA - CACO-2 [nTPM]":"17.2","Cell RNA - CAPAN-2 [nTPM]":"0.5","Cell RNA - Daudi [nTPM]":"13.7","Cell RNA - EFO-21 [nTPM]":"0.6","Cell RNA - fHDF\/TERT166 [nTPM]":"5.4","Cell RNA - GAMG [nTPM]":"3.9","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"3.6","Cell RNA - HBEC3-KT [nTPM]":"5.7","Cell RNA - HBF TERT88 [nTPM]":"2.9","Cell RNA - HDLM-2 [nTPM]":"70.9","Cell RNA - HEK 293 [nTPM]":"4.5","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"13.6","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.8","Cell RNA - HL-60 [nTPM]":"0.9","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"2.0","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"1.6","Cell RNA - HUVEC TERT2 [nTPM]":"32.5","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"2.2","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"4.2","Cell RNA - OE19 [nTPM]":"10.5","Cell RNA - PC-3 [nTPM]":"1.8","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"66.4","Cell RNA - RT4 [nTPM]":"6.1","Cell RNA - SCLC-21H [nTPM]":"2.2","Cell RNA - SH-SY5Y [nTPM]":"2.0","Cell RNA - SiHa [nTPM]":"0.8","Cell RNA - SK-BR-3 [nTPM]":"3.8","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"7.7","Cell RNA - T-47d [nTPM]":"1.4","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"17.6","Cell RNA - U-138 MG [nTPM]":"4.9","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"9.5","Cell RNA - U-251 MG [nTPM]":"3.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"23.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"13.2","Brain RNA - basal ganglia [nTPM]":"15.4","Brain RNA - cerebellum [nTPM]":"9.5","Brain RNA - cerebral cortex [nTPM]":"14.8","Brain RNA - hippocampal formation [nTPM]":"16.5","Brain RNA - hypothalamus [nTPM]":"12.6","Brain RNA - medulla oblongata [nTPM]":"10.8","Brain RNA - midbrain [nTPM]":"13.0","Brain RNA - pons [nTPM]":"13.6","Brain RNA - spinal cord [nTPM]":"10.9","Brain RNA - thalamus [nTPM]":"13.9","Brain RNA - white matter [nTPM]":"10.1","Single Cell Type RNA - Adipocytes [nTPM]":"12.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"163.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.2","Single Cell Type RNA - Astrocytes [nTPM]":"4.2","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"3.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"28.6","Single Cell Type RNA - Club cells [nTPM]":"6.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"52.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.1","Single Cell Type RNA - Early spermatids [nTPM]":"4.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.3","Single Cell Type RNA - Endothelial cells [nTPM]":"10.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"48.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"98.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"68.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"50.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"11.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"1.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"67.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"161.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.3","Single Cell Type RNA - Paneth cells [nTPM]":"10.6","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"110.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"43.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"1.4","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.5","Single Cell Type RNA - Urothelial cells [nTPM]":"1.8"},{"Gene":"SLC1A2","Gene synonym":["EAAT2","GLT-1"],"Ensembl":"ENSG00000110436","Gene description":"Solute carrier family 1 member 2","Uniprot":["P43004"],"Chromosome":"11","Position":"35251205-35420063","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"782.3","choroid plexus":"202.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Astrocytes":"4607.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"28.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"1.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC TERT1":"2.1","BJ hTERT+":"2.4","fHDF\/TERT166":"1.7","Hep G2":"2.9","NTERA-2":"3.1","SCLC-21H":"1.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002574","HPA009172","HPA067499"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002574":"AB_564087","HPA009172":"AB_1849764","HPA067499":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.6","Tissue RNA - adrenal gland [nTPM]":"4.6","Tissue RNA - amygdala [nTPM]":"546.9","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"731.2","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"3.8","Tissue RNA - cerebellum [nTPM]":"388.1","Tissue RNA - cerebral cortex [nTPM]":"782.3","Tissue RNA - cervix [nTPM]":"1.2","Tissue RNA - choroid plexus [nTPM]":"202.7","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"1.0","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"0.9","Tissue RNA - hippocampal formation [nTPM]":"631.1","Tissue RNA - hypothalamus [nTPM]":"432.5","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"34.9","Tissue RNA - lung [nTPM]":"0.6","Tissue RNA - lymph node [nTPM]":"1.9","Tissue RNA - medulla oblongata [nTPM]":"450.6","Tissue RNA - midbrain [nTPM]":"533.6","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"9.5","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"2.6","Tissue RNA - placenta [nTPM]":"1.1","Tissue RNA - pons [nTPM]":"384.2","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"60.1","Tissue RNA - salivary gland [nTPM]":"4.6","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"1.3","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"409.7","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"2.1","Tissue RNA - testis [nTPM]":"1.7","Tissue RNA - thalamus [nTPM]":"498.7","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.5","Tissue RNA - tonsil [nTPM]":"1.6","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"453.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"2.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.5","Cell RNA - BJ hTERT+ [nTPM]":"2.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"1.7","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"2.9","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.4","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"3.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"1.6","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"1.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.5","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.5","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"1.3","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"546.9","Brain RNA - basal ganglia [nTPM]":"731.2","Brain RNA - cerebellum [nTPM]":"388.1","Brain RNA - cerebral cortex [nTPM]":"782.3","Brain RNA - hippocampal formation [nTPM]":"631.1","Brain RNA - hypothalamus [nTPM]":"432.5","Brain RNA - medulla oblongata [nTPM]":"450.6","Brain RNA - midbrain [nTPM]":"533.6","Brain RNA - pons [nTPM]":"384.2","Brain RNA - spinal cord [nTPM]":"409.7","Brain RNA - thalamus [nTPM]":"498.7","Brain RNA - white matter [nTPM]":"453.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"4607.2","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"109.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"148.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"96.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.7","Single Cell Type RNA - Endothelial cells [nTPM]":"1.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"83.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.0","Single Cell Type RNA - Fibroblasts [nTPM]":"3.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"6.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.3","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"81.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"3.0","Single Cell Type RNA - Late spermatids [nTPM]":"97.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"194.9","Single Cell Type RNA - monocytes [nTPM]":"31.6","Single Cell Type RNA - Muller glia cells [nTPM]":"10.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"634.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"161.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"269.4","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"SLC1A3","Gene synonym":["EA6","EAAT1","GLAST"],"Ensembl":"ENSG00000079215","Gene description":"Solute carrier family 1 member 3","Uniprot":["P43003"],"Chromosome":"5","Position":"36596588-36688334","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"brain":"776.8","choroid plexus":"400.6","retina":"221.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"1735.2","Microglial cells":"332.6","Muller glia cells":"472.6","Oligodendrocyte precursor cells":"237.7","Oligodendrocytes":"249.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"21","RNA cancer specific FPKM":{"glioma":"168.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"classical monocyte":"1.5","intermediate monocyte":"1.2","myeloid DC":"1.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"16","RNA blood lineage specific nTPM":{"dendritic cells":"1.6","monocytes":"1.5"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"50.0","CACO-2":"112.6","HaCaT":"71.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002573","HPA037467","HPA037468"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":["Nucleoli","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB002573":"AB_564088","HPA037467":"AB_10795027","HPA037468":"AB_10671371"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Tissue RNA - adipose tissue [nTPM]":"30.7","Tissue RNA - adrenal gland [nTPM]":"16.4","Tissue RNA - amygdala [nTPM]":"500.4","Tissue RNA - appendix [nTPM]":"7.4","Tissue RNA - basal ganglia [nTPM]":"544.2","Tissue RNA - bone marrow [nTPM]":"3.3","Tissue RNA - breast [nTPM]":"17.7","Tissue RNA - cerebellum [nTPM]":"549.4","Tissue RNA - cerebral cortex [nTPM]":"776.8","Tissue RNA - cervix [nTPM]":"8.7","Tissue RNA - choroid plexus [nTPM]":"400.6","Tissue RNA - colon [nTPM]":"3.0","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"1.6","Tissue RNA - epididymis [nTPM]":"1.1","Tissue RNA - esophagus [nTPM]":"10.5","Tissue RNA - fallopian tube [nTPM]":"6.0","Tissue RNA - gallbladder [nTPM]":"8.0","Tissue RNA - heart muscle [nTPM]":"45.4","Tissue RNA - hippocampal formation [nTPM]":"514.6","Tissue RNA - hypothalamus [nTPM]":"502.5","Tissue RNA - kidney [nTPM]":"2.2","Tissue RNA - liver [nTPM]":"3.8","Tissue RNA - lung [nTPM]":"10.2","Tissue RNA - lymph node [nTPM]":"17.4","Tissue RNA - medulla oblongata [nTPM]":"477.6","Tissue RNA - midbrain [nTPM]":"510.1","Tissue RNA - ovary [nTPM]":"12.6","Tissue RNA - pancreas [nTPM]":"5.0","Tissue RNA - parathyroid gland [nTPM]":"2.2","Tissue RNA - pituitary gland [nTPM]":"18.1","Tissue RNA - placenta [nTPM]":"20.3","Tissue RNA - pons [nTPM]":"502.4","Tissue RNA - prostate [nTPM]":"3.2","Tissue RNA - rectum [nTPM]":"1.1","Tissue RNA - retina [nTPM]":"221.1","Tissue RNA - salivary gland [nTPM]":"4.7","Tissue RNA - seminal vesicle [nTPM]":"4.7","Tissue RNA - skeletal muscle [nTPM]":"14.1","Tissue RNA - skin 1 [nTPM]":"6.0","Tissue RNA - small intestine [nTPM]":"3.2","Tissue RNA - smooth muscle [nTPM]":"4.1","Tissue RNA - spinal cord [nTPM]":"495.4","Tissue RNA - spleen [nTPM]":"9.3","Tissue RNA - stomach 1 [nTPM]":"2.2","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"532.8","Tissue RNA - thymus [nTPM]":"3.6","Tissue RNA - thyroid gland [nTPM]":"3.4","Tissue RNA - tongue [nTPM]":"9.2","Tissue RNA - tonsil [nTPM]":"5.4","Tissue RNA - urinary bladder [nTPM]":"7.0","Tissue RNA - vagina [nTPM]":"5.3","Tissue RNA - white matter [nTPM]":"494.9","Cell RNA - A-431 [nTPM]":"1.3","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"50.0","Cell RNA - AN3-CA [nTPM]":"5.3","Cell RNA - ASC diff [nTPM]":"5.9","Cell RNA - ASC TERT1 [nTPM]":"14.3","Cell RNA - BEWO [nTPM]":"37.7","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.9","Cell RNA - CACO-2 [nTPM]":"112.6","Cell RNA - CAPAN-2 [nTPM]":"5.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"27.8","Cell RNA - fHDF\/TERT166 [nTPM]":"2.3","Cell RNA - GAMG [nTPM]":"1.0","Cell RNA - HaCaT [nTPM]":"71.4","Cell RNA - HAP1 [nTPM]":"16.9","Cell RNA - HBEC3-KT [nTPM]":"9.1","Cell RNA - HBF TERT88 [nTPM]":"2.2","Cell RNA - HDLM-2 [nTPM]":"1.8","Cell RNA - HEK 293 [nTPM]":"33.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"2.5","Cell RNA - HL-60 [nTPM]":"1.3","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"26.9","Cell RNA - hTCEpi [nTPM]":"34.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.4","Cell RNA - hTERT-HME1 [nTPM]":"5.3","Cell RNA - hTERT-RPE1 [nTPM]":"1.8","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"1.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"8.7","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"6.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"5.9","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.5","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"3.1","Cell RNA - SCLC-21H [nTPM]":"4.7","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"5.1","Cell RNA - SK-BR-3 [nTPM]":"14.6","Cell RNA - SK-MEL-30 [nTPM]":"2.1","Cell RNA - SuSa [nTPM]":"24.4","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"3.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"6.2","Cell RNA - U-2 OS [nTPM]":"10.3","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"20.7","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"21.7","Cell RNA - U-937 [nTPM]":"37.7","Cell RNA - WM-115 [nTPM]":"12.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.5","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"1.6","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"500.4","Brain RNA - basal ganglia [nTPM]":"544.2","Brain RNA - cerebellum [nTPM]":"549.4","Brain RNA - cerebral cortex [nTPM]":"776.8","Brain RNA - hippocampal formation [nTPM]":"514.6","Brain RNA - hypothalamus [nTPM]":"502.5","Brain RNA - medulla oblongata [nTPM]":"477.6","Brain RNA - midbrain [nTPM]":"510.1","Brain RNA - pons [nTPM]":"502.4","Brain RNA - spinal cord [nTPM]":"495.4","Brain RNA - thalamus [nTPM]":"532.8","Brain RNA - white matter [nTPM]":"494.9","Single Cell Type RNA - Adipocytes [nTPM]":"1.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"1735.2","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"19.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"83.1","Single Cell Type RNA - Bipolar cells [nTPM]":"7.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"36.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"32.9","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.2","Single Cell Type RNA - Endothelial cells [nTPM]":"8.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.9","Single Cell Type RNA - Fibroblasts [nTPM]":"7.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"41.2","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"77.6","Single Cell Type RNA - Langerhans cells [nTPM]":"5.9","Single Cell Type RNA - Late spermatids [nTPM]":"4.1","Single Cell Type RNA - Leydig cells [nTPM]":"4.4","Single Cell Type RNA - Macrophages [nTPM]":"59.6","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"332.6","Single Cell Type RNA - monocytes [nTPM]":"3.3","Single Cell Type RNA - Muller glia cells [nTPM]":"472.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"237.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"249.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"32.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.2","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"20.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"3.6"},{"Gene":"SLC1A4","Gene synonym":["ASCT1","SATT"],"Ensembl":"ENSG00000115902","Gene description":"Solute carrier family 1 member 4","Uniprot":["P43007"],"Chromosome":"2","Position":"64988477-65023865","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"59.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"69.9","Granulosa cells":"49.2","Melanocytes":"85.4","Plasma cells":"65.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SK-MEL-30":"294.5","U-266\/70":"132.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034963","HPA034964"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 65: Plasmacytoid DCs - Unknown function","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA034963":"AB_2797223","HPA034964":"AB_2674386"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.59e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.23e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.87e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.3","Tissue RNA - adrenal gland [nTPM]":"26.4","Tissue RNA - amygdala [nTPM]":"49.1","Tissue RNA - appendix [nTPM]":"9.1","Tissue RNA - basal ganglia [nTPM]":"46.8","Tissue RNA - bone marrow [nTPM]":"13.4","Tissue RNA - breast [nTPM]":"13.6","Tissue RNA - cerebellum [nTPM]":"32.1","Tissue RNA - cerebral cortex [nTPM]":"48.6","Tissue RNA - cervix [nTPM]":"14.0","Tissue RNA - choroid plexus [nTPM]":"18.0","Tissue RNA - colon [nTPM]":"9.4","Tissue RNA - duodenum [nTPM]":"6.1","Tissue RNA - endometrium 1 [nTPM]":"12.8","Tissue RNA - epididymis [nTPM]":"8.2","Tissue RNA - esophagus [nTPM]":"7.5","Tissue RNA - fallopian tube [nTPM]":"4.8","Tissue RNA - gallbladder [nTPM]":"3.9","Tissue RNA - heart muscle [nTPM]":"6.2","Tissue RNA - hippocampal formation [nTPM]":"43.4","Tissue RNA - hypothalamus [nTPM]":"56.6","Tissue RNA - kidney [nTPM]":"1.9","Tissue RNA - liver [nTPM]":"9.0","Tissue RNA - lung [nTPM]":"4.9","Tissue RNA - lymph node [nTPM]":"10.7","Tissue RNA - medulla oblongata [nTPM]":"37.2","Tissue RNA - midbrain [nTPM]":"43.1","Tissue RNA - ovary [nTPM]":"13.2","Tissue RNA - pancreas [nTPM]":"29.6","Tissue RNA - parathyroid gland [nTPM]":"5.5","Tissue RNA - pituitary gland [nTPM]":"13.7","Tissue RNA - placenta [nTPM]":"6.6","Tissue RNA - pons [nTPM]":"52.1","Tissue RNA - prostate [nTPM]":"9.6","Tissue RNA - rectum [nTPM]":"8.4","Tissue RNA - retina [nTPM]":"19.3","Tissue RNA - salivary gland [nTPM]":"7.5","Tissue RNA - seminal vesicle [nTPM]":"7.1","Tissue RNA - skeletal muscle [nTPM]":"40.1","Tissue RNA - skin 1 [nTPM]":"18.6","Tissue RNA - small intestine [nTPM]":"5.6","Tissue RNA - smooth muscle [nTPM]":"12.3","Tissue RNA - spinal cord [nTPM]":"29.5","Tissue RNA - spleen [nTPM]":"7.5","Tissue RNA - stomach 1 [nTPM]":"8.1","Tissue RNA - testis [nTPM]":"11.7","Tissue RNA - thalamus [nTPM]":"59.9","Tissue RNA - thymus [nTPM]":"20.5","Tissue RNA - thyroid gland [nTPM]":"5.7","Tissue RNA - tongue [nTPM]":"17.0","Tissue RNA - tonsil [nTPM]":"19.0","Tissue RNA - urinary bladder [nTPM]":"4.8","Tissue RNA - vagina [nTPM]":"6.2","Tissue RNA - white matter [nTPM]":"30.3","Cell RNA - A-431 [nTPM]":"15.3","Cell RNA - A549 [nTPM]":"11.6","Cell RNA - AF22 [nTPM]":"6.6","Cell RNA - AN3-CA [nTPM]":"34.9","Cell RNA - ASC diff [nTPM]":"14.7","Cell RNA - ASC TERT1 [nTPM]":"9.5","Cell RNA - BEWO [nTPM]":"9.4","Cell RNA - BJ [nTPM]":"28.5","Cell RNA - BJ hTERT+ [nTPM]":"14.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.8","Cell RNA - CACO-2 [nTPM]":"3.2","Cell RNA - CAPAN-2 [nTPM]":"2.2","Cell RNA - Daudi [nTPM]":"49.7","Cell RNA - EFO-21 [nTPM]":"6.5","Cell RNA - fHDF\/TERT166 [nTPM]":"44.8","Cell RNA - GAMG [nTPM]":"14.7","Cell RNA - HaCaT [nTPM]":"43.2","Cell RNA - HAP1 [nTPM]":"13.7","Cell RNA - HBEC3-KT [nTPM]":"3.6","Cell RNA - HBF TERT88 [nTPM]":"12.0","Cell RNA - HDLM-2 [nTPM]":"20.1","Cell RNA - HEK 293 [nTPM]":"5.4","Cell RNA - HEL [nTPM]":"26.0","Cell RNA - HeLa [nTPM]":"13.1","Cell RNA - Hep G2 [nTPM]":"30.9","Cell RNA - HHSteC [nTPM]":"31.0","Cell RNA - HL-60 [nTPM]":"43.8","Cell RNA - HMC-1 [nTPM]":"23.1","Cell RNA - HSkMC [nTPM]":"4.4","Cell RNA - hTCEpi [nTPM]":"73.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.8","Cell RNA - hTERT-HME1 [nTPM]":"24.2","Cell RNA - hTERT-RPE1 [nTPM]":"3.9","Cell RNA - HUVEC TERT2 [nTPM]":"7.3","Cell RNA - JURKAT [nTPM]":"49.1","Cell RNA - K-562 [nTPM]":"20.7","Cell RNA - Karpas-707 [nTPM]":"122.0","Cell RNA - LHCN-M2 [nTPM]":"8.4","Cell RNA - MCF7 [nTPM]":"13.5","Cell RNA - MOLT-4 [nTPM]":"37.7","Cell RNA - NB-4 [nTPM]":"29.1","Cell RNA - NTERA-2 [nTPM]":"4.7","Cell RNA - OE19 [nTPM]":"20.1","Cell RNA - PC-3 [nTPM]":"13.9","Cell RNA - REH [nTPM]":"13.5","Cell RNA - RH-30 [nTPM]":"1.9","Cell RNA - RPMI-8226 [nTPM]":"125.5","Cell RNA - RPTEC TERT1 [nTPM]":"4.9","Cell RNA - RT4 [nTPM]":"7.7","Cell RNA - SCLC-21H [nTPM]":"29.3","Cell RNA - SH-SY5Y [nTPM]":"14.1","Cell RNA - SiHa [nTPM]":"17.9","Cell RNA - SK-BR-3 [nTPM]":"16.1","Cell RNA - SK-MEL-30 [nTPM]":"294.5","Cell RNA - SuSa [nTPM]":"3.0","Cell RNA - T-47d [nTPM]":"19.3","Cell RNA - THP-1 [nTPM]":"47.8","Cell RNA - TIME [nTPM]":"1.6","Cell RNA - U-138 MG [nTPM]":"16.0","Cell RNA - U-2 OS [nTPM]":"19.0","Cell RNA - U-2197 [nTPM]":"31.2","Cell RNA - U-251 MG [nTPM]":"17.5","Cell RNA - U-266\/70 [nTPM]":"132.8","Cell RNA - U-266\/84 [nTPM]":"71.2","Cell RNA - U-698 [nTPM]":"118.8","Cell RNA - U-87 MG [nTPM]":"23.6","Cell RNA - U-937 [nTPM]":"86.5","Cell RNA - WM-115 [nTPM]":"86.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.1","Blood RNA - eosinophil [nTPM]":"1.8","Blood RNA - gdT-cell [nTPM]":"0.9","Blood RNA - intermediate monocyte [nTPM]":"4.8","Blood RNA - MAIT T-cell [nTPM]":"1.2","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.5","Blood RNA - myeloid DC [nTPM]":"3.9","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.8","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"5.1","Blood RNA - non-classical monocyte [nTPM]":"9.4","Blood RNA - plasmacytoid DC [nTPM]":"7.2","Blood RNA - T-reg [nTPM]":"3.5","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"49.1","Brain RNA - basal ganglia [nTPM]":"46.8","Brain RNA - cerebellum [nTPM]":"32.1","Brain RNA - cerebral cortex [nTPM]":"48.6","Brain RNA - hippocampal formation [nTPM]":"43.4","Brain RNA - hypothalamus [nTPM]":"56.6","Brain RNA - medulla oblongata [nTPM]":"37.2","Brain RNA - midbrain [nTPM]":"43.1","Brain RNA - pons [nTPM]":"52.1","Brain RNA - spinal cord [nTPM]":"29.5","Brain RNA - thalamus [nTPM]":"59.9","Brain RNA - white matter [nTPM]":"30.3","Single Cell Type RNA - Adipocytes [nTPM]":"3.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.7","Single Cell Type RNA - Astrocytes [nTPM]":"69.9","Single Cell Type RNA - B-cells [nTPM]":"13.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"46.1","Single Cell Type RNA - Bipolar cells [nTPM]":"6.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"1.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.4","Single Cell Type RNA - dendritic cells [nTPM]":"20.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.0","Single Cell Type RNA - Early spermatids [nTPM]":"32.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.2","Single Cell Type RNA - Endothelial cells [nTPM]":"5.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"6.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"20.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.3","Single Cell Type RNA - Fibroblasts [nTPM]":"4.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.6","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"49.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"13.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.7","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"6.8","Single Cell Type RNA - Langerhans cells [nTPM]":"11.8","Single Cell Type RNA - Late spermatids [nTPM]":"47.5","Single Cell Type RNA - Leydig cells [nTPM]":"11.1","Single Cell Type RNA - Macrophages [nTPM]":"11.1","Single Cell Type RNA - Melanocytes [nTPM]":"85.4","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"5.1","Single Cell Type RNA - Muller glia cells [nTPM]":"14.6","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.8","Single Cell Type RNA - Peritubular cells [nTPM]":"29.7","Single Cell Type RNA - Plasma cells [nTPM]":"65.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.3","Single Cell Type RNA - Spermatocytes [nTPM]":"2.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - T-cells [nTPM]":"10.9","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.8","Single Cell Type RNA - Urothelial cells [nTPM]":"1.0"},{"Gene":"SLC20A2","Gene synonym":["Glvr-2","GLVR2","MLVAR","PiT-2","Ram-1"],"Ensembl":"ENSG00000168575","Gene description":"Solute carrier family 20 member 2","Uniprot":["Q08357"],"Chromosome":"8","Position":"42416475-42541926","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction","Ion transport","Phosphate transport","Sodium transport","Symport","Transport"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"130.6","skeletal muscle":"131.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"250.2","Oligodendrocytes":"151.7","Urothelial cells":"170.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"132.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026540"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026540":"AB_1855408"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.67e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.01e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.9","Tissue RNA - adrenal gland [nTPM]":"8.0","Tissue RNA - amygdala [nTPM]":"33.4","Tissue RNA - appendix [nTPM]":"9.8","Tissue RNA - basal ganglia [nTPM]":"45.3","Tissue RNA - bone marrow [nTPM]":"3.0","Tissue RNA - breast [nTPM]":"12.1","Tissue RNA - cerebellum [nTPM]":"55.4","Tissue RNA - cerebral cortex [nTPM]":"37.1","Tissue RNA - cervix [nTPM]":"15.8","Tissue RNA - choroid plexus [nTPM]":"130.6","Tissue RNA - colon [nTPM]":"22.8","Tissue RNA - duodenum [nTPM]":"46.7","Tissue RNA - endometrium 1 [nTPM]":"18.5","Tissue RNA - epididymis [nTPM]":"9.9","Tissue RNA - esophagus [nTPM]":"32.7","Tissue RNA - fallopian tube [nTPM]":"24.5","Tissue RNA - gallbladder [nTPM]":"15.1","Tissue RNA - heart muscle [nTPM]":"63.2","Tissue RNA - hippocampal formation [nTPM]":"30.1","Tissue RNA - hypothalamus [nTPM]":"48.7","Tissue RNA - kidney [nTPM]":"17.5","Tissue RNA - liver [nTPM]":"39.7","Tissue RNA - lung [nTPM]":"15.1","Tissue RNA - lymph node [nTPM]":"6.5","Tissue RNA - medulla oblongata [nTPM]":"46.5","Tissue RNA - midbrain [nTPM]":"56.5","Tissue RNA - ovary [nTPM]":"8.1","Tissue RNA - pancreas [nTPM]":"51.6","Tissue RNA - parathyroid gland [nTPM]":"15.0","Tissue RNA - pituitary gland [nTPM]":"10.5","Tissue RNA - placenta [nTPM]":"13.5","Tissue RNA - pons [nTPM]":"47.5","Tissue RNA - prostate [nTPM]":"13.6","Tissue RNA - rectum [nTPM]":"19.0","Tissue RNA - retina [nTPM]":"7.5","Tissue RNA - salivary gland [nTPM]":"87.9","Tissue RNA - seminal vesicle [nTPM]":"17.6","Tissue RNA - skeletal muscle [nTPM]":"131.2","Tissue RNA - skin 1 [nTPM]":"23.3","Tissue RNA - small intestine [nTPM]":"18.8","Tissue RNA - smooth muscle [nTPM]":"17.9","Tissue RNA - spinal cord [nTPM]":"42.7","Tissue RNA - spleen [nTPM]":"7.4","Tissue RNA - stomach 1 [nTPM]":"15.1","Tissue RNA - testis [nTPM]":"15.9","Tissue RNA - thalamus [nTPM]":"67.8","Tissue RNA - thymus [nTPM]":"11.9","Tissue RNA - thyroid gland [nTPM]":"82.8","Tissue RNA - tongue [nTPM]":"57.6","Tissue RNA - tonsil [nTPM]":"9.1","Tissue RNA - urinary bladder [nTPM]":"22.0","Tissue RNA - vagina [nTPM]":"21.7","Tissue RNA - white matter [nTPM]":"52.8","Cell RNA - A-431 [nTPM]":"52.7","Cell RNA - A549 [nTPM]":"14.3","Cell RNA - AF22 [nTPM]":"19.0","Cell RNA - AN3-CA [nTPM]":"16.0","Cell RNA - ASC diff [nTPM]":"10.4","Cell RNA - ASC TERT1 [nTPM]":"8.8","Cell RNA - BEWO [nTPM]":"41.1","Cell RNA - BJ [nTPM]":"46.9","Cell RNA - BJ hTERT+ [nTPM]":"80.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"58.7","Cell RNA - CACO-2 [nTPM]":"38.9","Cell RNA - CAPAN-2 [nTPM]":"132.9","Cell RNA - Daudi [nTPM]":"17.4","Cell RNA - EFO-21 [nTPM]":"53.6","Cell RNA - fHDF\/TERT166 [nTPM]":"42.1","Cell RNA - GAMG [nTPM]":"13.5","Cell RNA - HaCaT [nTPM]":"81.1","Cell RNA - HAP1 [nTPM]":"11.4","Cell RNA - HBEC3-KT [nTPM]":"45.2","Cell RNA - HBF TERT88 [nTPM]":"41.6","Cell RNA - HDLM-2 [nTPM]":"4.3","Cell RNA - HEK 293 [nTPM]":"8.7","Cell RNA - HEL [nTPM]":"27.8","Cell RNA - HeLa [nTPM]":"4.8","Cell RNA - Hep G2 [nTPM]":"22.0","Cell RNA - HHSteC [nTPM]":"14.9","Cell RNA - HL-60 [nTPM]":"9.9","Cell RNA - HMC-1 [nTPM]":"12.3","Cell RNA - HSkMC [nTPM]":"9.5","Cell RNA - hTCEpi [nTPM]":"40.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"24.7","Cell RNA - hTERT-HME1 [nTPM]":"22.7","Cell RNA - hTERT-RPE1 [nTPM]":"16.7","Cell RNA - HUVEC TERT2 [nTPM]":"12.0","Cell RNA - JURKAT [nTPM]":"13.7","Cell RNA - K-562 [nTPM]":"27.2","Cell RNA - Karpas-707 [nTPM]":"14.0","Cell RNA - LHCN-M2 [nTPM]":"47.3","Cell RNA - MCF7 [nTPM]":"14.4","Cell RNA - MOLT-4 [nTPM]":"18.1","Cell RNA - NB-4 [nTPM]":"16.1","Cell RNA - NTERA-2 [nTPM]":"19.2","Cell RNA - OE19 [nTPM]":"50.5","Cell RNA - PC-3 [nTPM]":"8.8","Cell RNA - REH [nTPM]":"14.9","Cell RNA - RH-30 [nTPM]":"20.9","Cell RNA - RPMI-8226 [nTPM]":"18.5","Cell RNA - RPTEC TERT1 [nTPM]":"21.4","Cell RNA - RT4 [nTPM]":"47.5","Cell RNA - SCLC-21H [nTPM]":"5.1","Cell RNA - SH-SY5Y [nTPM]":"19.2","Cell RNA - SiHa [nTPM]":"12.8","Cell RNA - SK-BR-3 [nTPM]":"21.8","Cell RNA - SK-MEL-30 [nTPM]":"12.8","Cell RNA - SuSa [nTPM]":"15.0","Cell RNA - T-47d [nTPM]":"17.5","Cell RNA - THP-1 [nTPM]":"17.3","Cell RNA - TIME [nTPM]":"34.9","Cell RNA - U-138 MG [nTPM]":"50.0","Cell RNA - U-2 OS [nTPM]":"17.4","Cell RNA - U-2197 [nTPM]":"12.3","Cell RNA - U-251 MG [nTPM]":"25.7","Cell RNA - U-266\/70 [nTPM]":"9.0","Cell RNA - U-266\/84 [nTPM]":"22.2","Cell RNA - U-698 [nTPM]":"12.6","Cell RNA - U-87 MG [nTPM]":"15.8","Cell RNA - U-937 [nTPM]":"19.5","Cell RNA - WM-115 [nTPM]":"28.3","Blood RNA - basophil [nTPM]":"3.2","Blood RNA - classical monocyte [nTPM]":"2.2","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"3.6","Blood RNA - intermediate monocyte [nTPM]":"1.6","Blood RNA - MAIT T-cell [nTPM]":"4.3","Blood RNA - memory B-cell [nTPM]":"2.1","Blood RNA - memory CD4 T-cell [nTPM]":"4.0","Blood RNA - memory CD8 T-cell [nTPM]":"3.5","Blood RNA - myeloid DC [nTPM]":"3.7","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"4.8","Blood RNA - naive CD8 T-cell [nTPM]":"3.7","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"6.8","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"2.0","Blood RNA - T-reg [nTPM]":"4.1","Blood RNA - total PBMC [nTPM]":"3.1","Brain RNA - amygdala [nTPM]":"33.4","Brain RNA - basal ganglia [nTPM]":"45.3","Brain RNA - cerebellum [nTPM]":"55.4","Brain RNA - cerebral cortex [nTPM]":"37.1","Brain RNA - hippocampal formation [nTPM]":"30.1","Brain RNA - hypothalamus [nTPM]":"48.7","Brain RNA - medulla oblongata [nTPM]":"46.5","Brain RNA - midbrain [nTPM]":"56.5","Brain RNA - pons [nTPM]":"47.5","Brain RNA - spinal cord [nTPM]":"42.7","Brain RNA - thalamus [nTPM]":"67.8","Brain RNA - white matter [nTPM]":"52.8","Single Cell Type RNA - Adipocytes [nTPM]":"11.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.6","Single Cell Type RNA - Astrocytes [nTPM]":"51.6","Single Cell Type RNA - B-cells [nTPM]":"9.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"98.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"250.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"96.2","Single Cell Type RNA - Bipolar cells [nTPM]":"13.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"60.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"21.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.9","Single Cell Type RNA - dendritic cells [nTPM]":"14.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"76.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"29.6","Single Cell Type RNA - Early spermatids [nTPM]":"10.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"79.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.8","Single Cell Type RNA - Endothelial cells [nTPM]":"18.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.0","Single Cell Type RNA - Erythroid cells [nTPM]":"6.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"88.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"31.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"23.7","Single Cell Type RNA - Fibroblasts [nTPM]":"15.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"61.2","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"17.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"30.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.2","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"88.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.5","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"7.7","Single Cell Type RNA - Langerhans cells [nTPM]":"12.2","Single Cell Type RNA - Late spermatids [nTPM]":"10.0","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"10.2","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"78.7","Single Cell Type RNA - monocytes [nTPM]":"7.3","Single Cell Type RNA - Muller glia cells [nTPM]":"14.4","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"63.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"151.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"47.4","Single Cell Type RNA - Paneth cells [nTPM]":"35.8","Single Cell Type RNA - Peritubular cells [nTPM]":"11.7","Single Cell Type RNA - Plasma cells [nTPM]":"8.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"76.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"57.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"28.3","Single Cell Type RNA - Spermatocytes [nTPM]":"5.2","Single Cell Type RNA - Spermatogonia [nTPM]":"7.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"73.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"74.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"25.4","Single Cell Type RNA - T-cells [nTPM]":"14.2","Single Cell Type RNA - Theca cells [nTPM]":"23.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.5","Single Cell Type RNA - Urothelial cells [nTPM]":"170.3"},{"Gene":"SLC22A18","Gene synonym":["BWR1A","BWSCR1A","IMPT1","ITM","ORCTL2","SLC22A1L","TSSC5"],"Ensembl":"ENSG00000110628","Gene description":"Solute carrier family 22 member 18","Uniprot":["Q96BI1"],"Chromosome":"11","Position":"2899721-2925246","Protein class":["Disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"42.3","liver":"45.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"368.4","Late spermatids":"499.1","Paneth cells":"385.7","Proximal enterocytes":"730.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"33.4","Karpas-707":"29.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067812","HPA071461"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA067812":"AB_2685902","HPA071461":"AB_2686401"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.9","Tissue RNA - adrenal gland [nTPM]":"3.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"2.1","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"1.5","Tissue RNA - breast [nTPM]":"6.7","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"1.2","Tissue RNA - cervix [nTPM]":"6.5","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"27.8","Tissue RNA - duodenum [nTPM]":"42.3","Tissue RNA - endometrium 1 [nTPM]":"6.8","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"13.3","Tissue RNA - fallopian tube [nTPM]":"8.2","Tissue RNA - gallbladder [nTPM]":"4.0","Tissue RNA - heart muscle [nTPM]":"16.7","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"1.0","Tissue RNA - kidney [nTPM]":"16.7","Tissue RNA - liver [nTPM]":"45.2","Tissue RNA - lung [nTPM]":"6.8","Tissue RNA - lymph node [nTPM]":"2.3","Tissue RNA - medulla oblongata [nTPM]":"0.6","Tissue RNA - midbrain [nTPM]":"0.5","Tissue RNA - ovary [nTPM]":"4.8","Tissue RNA - pancreas [nTPM]":"6.4","Tissue RNA - parathyroid gland [nTPM]":"1.7","Tissue RNA - pituitary gland [nTPM]":"3.2","Tissue RNA - placenta [nTPM]":"5.4","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"8.0","Tissue RNA - rectum [nTPM]":"4.2","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"10.3","Tissue RNA - seminal vesicle [nTPM]":"2.8","Tissue RNA - skeletal muscle [nTPM]":"1.7","Tissue RNA - skin 1 [nTPM]":"16.1","Tissue RNA - small intestine [nTPM]":"28.0","Tissue RNA - smooth muscle [nTPM]":"0.9","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"9.1","Tissue RNA - stomach 1 [nTPM]":"11.3","Tissue RNA - testis [nTPM]":"2.1","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"0.7","Tissue RNA - thyroid gland [nTPM]":"12.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"1.1","Tissue RNA - urinary bladder [nTPM]":"6.5","Tissue RNA - vagina [nTPM]":"9.7","Tissue RNA - white matter [nTPM]":"0.8","Cell RNA - A-431 [nTPM]":"2.3","Cell RNA - A549 [nTPM]":"14.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"7.2","Cell RNA - ASC diff [nTPM]":"1.3","Cell RNA - ASC TERT1 [nTPM]":"2.0","Cell RNA - BEWO [nTPM]":"5.8","Cell RNA - BJ [nTPM]":"4.4","Cell RNA - BJ hTERT+ [nTPM]":"7.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.2","Cell RNA - CACO-2 [nTPM]":"8.0","Cell RNA - CAPAN-2 [nTPM]":"33.4","Cell RNA - Daudi [nTPM]":"1.0","Cell RNA - EFO-21 [nTPM]":"14.1","Cell RNA - fHDF\/TERT166 [nTPM]":"5.8","Cell RNA - GAMG [nTPM]":"5.6","Cell RNA - HaCaT [nTPM]":"7.3","Cell RNA - HAP1 [nTPM]":"0.4","Cell RNA - HBEC3-KT [nTPM]":"0.7","Cell RNA - HBF TERT88 [nTPM]":"0.5","Cell RNA - HDLM-2 [nTPM]":"6.8","Cell RNA - HEK 293 [nTPM]":"1.3","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"3.3","Cell RNA - Hep G2 [nTPM]":"7.4","Cell RNA - HHSteC [nTPM]":"13.5","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"6.2","Cell RNA - HSkMC [nTPM]":"5.7","Cell RNA - hTCEpi [nTPM]":"1.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.1","Cell RNA - hTERT-HME1 [nTPM]":"0.4","Cell RNA - hTERT-RPE1 [nTPM]":"2.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"4.5","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"29.1","Cell RNA - LHCN-M2 [nTPM]":"1.4","Cell RNA - MCF7 [nTPM]":"6.8","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"0.7","Cell RNA - OE19 [nTPM]":"10.6","Cell RNA - PC-3 [nTPM]":"3.3","Cell RNA - REH [nTPM]":"2.6","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"4.7","Cell RNA - RPTEC TERT1 [nTPM]":"1.1","Cell RNA - RT4 [nTPM]":"4.2","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"2.5","Cell RNA - SiHa [nTPM]":"1.8","Cell RNA - SK-BR-3 [nTPM]":"17.6","Cell RNA - SK-MEL-30 [nTPM]":"15.7","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"3.6","Cell RNA - THP-1 [nTPM]":"3.8","Cell RNA - TIME [nTPM]":"0.5","Cell RNA - U-138 MG [nTPM]":"1.9","Cell RNA - U-2 OS [nTPM]":"4.2","Cell RNA - U-2197 [nTPM]":"6.1","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"5.5","Cell RNA - U-266\/84 [nTPM]":"1.4","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"7.7","Cell RNA - U-937 [nTPM]":"3.9","Cell RNA - WM-115 [nTPM]":"7.5","Blood RNA - basophil [nTPM]":"32.1","Blood RNA - classical monocyte [nTPM]":"28.7","Blood RNA - eosinophil [nTPM]":"27.4","Blood RNA - gdT-cell [nTPM]":"6.8","Blood RNA - intermediate monocyte [nTPM]":"28.2","Blood RNA - MAIT T-cell [nTPM]":"3.7","Blood RNA - memory B-cell [nTPM]":"4.2","Blood RNA - memory CD4 T-cell [nTPM]":"5.1","Blood RNA - memory CD8 T-cell [nTPM]":"4.8","Blood RNA - myeloid DC [nTPM]":"17.9","Blood RNA - naive B-cell [nTPM]":"3.0","Blood RNA - naive CD4 T-cell [nTPM]":"2.7","Blood RNA - naive CD8 T-cell [nTPM]":"4.0","Blood RNA - neutrophil [nTPM]":"42.3","Blood RNA - NK-cell [nTPM]":"6.3","Blood RNA - non-classical monocyte [nTPM]":"22.9","Blood RNA - plasmacytoid DC [nTPM]":"13.2","Blood RNA - T-reg [nTPM]":"9.4","Blood RNA - total PBMC [nTPM]":"13.5","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"1.2","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"1.0","Brain RNA - medulla oblongata [nTPM]":"0.6","Brain RNA - midbrain [nTPM]":"0.5","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"0.8","Single Cell Type RNA - Adipocytes [nTPM]":"1.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.6","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"5.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"48.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"1.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"54.3","Single Cell Type RNA - Club cells [nTPM]":"29.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"102.6","Single Cell Type RNA - dendritic cells [nTPM]":"9.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"368.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"31.4","Single Cell Type RNA - Early spermatids [nTPM]":"161.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.3","Single Cell Type RNA - Endothelial cells [nTPM]":"2.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.8","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.9","Single Cell Type RNA - Fibroblasts [nTPM]":"9.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"47.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.1","Single Cell Type RNA - granulocytes [nTPM]":"15.9","Single Cell Type RNA - Granulosa cells [nTPM]":"7.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"158.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"46.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"93.2","Single Cell Type RNA - Ionocytes [nTPM]":"52.9","Single Cell Type RNA - Kupffer cells [nTPM]":"33.0","Single Cell Type RNA - Langerhans cells [nTPM]":"16.7","Single Cell Type RNA - Late spermatids [nTPM]":"499.1","Single Cell Type RNA - Leydig cells [nTPM]":"10.5","Single Cell Type RNA - Macrophages [nTPM]":"23.5","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"18.8","Single Cell Type RNA - Muller glia cells [nTPM]":"6.9","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.5","Single Cell Type RNA - Paneth cells [nTPM]":"385.7","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"3.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"730.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"122.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"26.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.2","Single Cell Type RNA - Spermatocytes [nTPM]":"5.8","Single Cell Type RNA - Spermatogonia [nTPM]":"4.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"181.3","Single Cell Type RNA - T-cells [nTPM]":"13.7","Single Cell Type RNA - Theca cells [nTPM]":"7.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"121.3","Single Cell Type RNA - Urothelial cells [nTPM]":"20.3"},{"Gene":"SLC22A5","Gene synonym":["CDSP","OCTN2","SCD"],"Ensembl":"ENSG00000197375","Gene description":"Solute carrier family 22 member 5","Uniprot":["O76082"],"Chromosome":"5","Position":"132369710-132395613","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"56.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"63.9","Proximal enterocytes":"56.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"8.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"34.7","SiHa":"37.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063062"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA063062":"AB_2684934"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.87e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.36e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.36e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.3","Tissue RNA - adrenal gland [nTPM]":"6.6","Tissue RNA - amygdala [nTPM]":"7.5","Tissue RNA - appendix [nTPM]":"2.0","Tissue RNA - basal ganglia [nTPM]":"7.9","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"4.9","Tissue RNA - cerebellum [nTPM]":"7.8","Tissue RNA - cerebral cortex [nTPM]":"7.8","Tissue RNA - cervix [nTPM]":"5.0","Tissue RNA - choroid plexus [nTPM]":"14.4","Tissue RNA - colon [nTPM]":"12.4","Tissue RNA - duodenum [nTPM]":"13.7","Tissue RNA - endometrium 1 [nTPM]":"4.0","Tissue RNA - epididymis [nTPM]":"11.1","Tissue RNA - esophagus [nTPM]":"3.9","Tissue RNA - fallopian tube [nTPM]":"8.4","Tissue RNA - gallbladder [nTPM]":"4.1","Tissue RNA - heart muscle [nTPM]":"14.2","Tissue RNA - hippocampal formation [nTPM]":"7.3","Tissue RNA - hypothalamus [nTPM]":"8.0","Tissue RNA - kidney [nTPM]":"26.7","Tissue RNA - liver [nTPM]":"7.8","Tissue RNA - lung [nTPM]":"3.2","Tissue RNA - lymph node [nTPM]":"1.2","Tissue RNA - medulla oblongata [nTPM]":"7.8","Tissue RNA - midbrain [nTPM]":"7.8","Tissue RNA - ovary [nTPM]":"5.6","Tissue RNA - pancreas [nTPM]":"8.2","Tissue RNA - parathyroid gland [nTPM]":"17.9","Tissue RNA - pituitary gland [nTPM]":"11.0","Tissue RNA - placenta [nTPM]":"4.2","Tissue RNA - pons [nTPM]":"7.4","Tissue RNA - prostate [nTPM]":"9.1","Tissue RNA - rectum [nTPM]":"9.4","Tissue RNA - retina [nTPM]":"3.7","Tissue RNA - salivary gland [nTPM]":"6.4","Tissue RNA - seminal vesicle [nTPM]":"11.2","Tissue RNA - skeletal muscle [nTPM]":"56.1","Tissue RNA - skin 1 [nTPM]":"6.0","Tissue RNA - small intestine [nTPM]":"16.9","Tissue RNA - smooth muscle [nTPM]":"2.5","Tissue RNA - spinal cord [nTPM]":"7.5","Tissue RNA - spleen [nTPM]":"2.5","Tissue RNA - stomach 1 [nTPM]":"6.0","Tissue RNA - testis [nTPM]":"3.8","Tissue RNA - thalamus [nTPM]":"8.0","Tissue RNA - thymus [nTPM]":"2.1","Tissue RNA - thyroid gland [nTPM]":"5.4","Tissue RNA - tongue [nTPM]":"22.3","Tissue RNA - tonsil [nTPM]":"1.8","Tissue RNA - urinary bladder [nTPM]":"5.0","Tissue RNA - vagina [nTPM]":"5.0","Tissue RNA - white matter [nTPM]":"7.8","Cell RNA - A-431 [nTPM]":"6.1","Cell RNA - A549 [nTPM]":"14.4","Cell RNA - AF22 [nTPM]":"0.9","Cell RNA - AN3-CA [nTPM]":"11.3","Cell RNA - ASC diff [nTPM]":"4.4","Cell RNA - ASC TERT1 [nTPM]":"2.1","Cell RNA - BEWO [nTPM]":"19.3","Cell RNA - BJ [nTPM]":"2.7","Cell RNA - BJ hTERT+ [nTPM]":"2.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.2","Cell RNA - CACO-2 [nTPM]":"10.7","Cell RNA - CAPAN-2 [nTPM]":"12.2","Cell RNA - Daudi [nTPM]":"2.9","Cell RNA - EFO-21 [nTPM]":"6.0","Cell RNA - fHDF\/TERT166 [nTPM]":"2.6","Cell RNA - GAMG [nTPM]":"13.1","Cell RNA - HaCaT [nTPM]":"14.3","Cell RNA - HAP1 [nTPM]":"9.4","Cell RNA - HBEC3-KT [nTPM]":"7.0","Cell RNA - HBF TERT88 [nTPM]":"5.3","Cell RNA - HDLM-2 [nTPM]":"3.6","Cell RNA - HEK 293 [nTPM]":"11.6","Cell RNA - HEL [nTPM]":"1.5","Cell RNA - HeLa [nTPM]":"34.7","Cell RNA - Hep G2 [nTPM]":"4.9","Cell RNA - HHSteC [nTPM]":"7.3","Cell RNA - HL-60 [nTPM]":"2.4","Cell RNA - HMC-1 [nTPM]":"2.4","Cell RNA - HSkMC [nTPM]":"2.0","Cell RNA - hTCEpi [nTPM]":"12.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.1","Cell RNA - hTERT-HME1 [nTPM]":"15.8","Cell RNA - hTERT-RPE1 [nTPM]":"7.6","Cell RNA - HUVEC TERT2 [nTPM]":"1.2","Cell RNA - JURKAT [nTPM]":"5.2","Cell RNA - K-562 [nTPM]":"6.8","Cell RNA - Karpas-707 [nTPM]":"1.8","Cell RNA - LHCN-M2 [nTPM]":"4.4","Cell RNA - MCF7 [nTPM]":"10.4","Cell RNA - MOLT-4 [nTPM]":"3.6","Cell RNA - NB-4 [nTPM]":"2.4","Cell RNA - NTERA-2 [nTPM]":"1.0","Cell RNA - OE19 [nTPM]":"10.5","Cell RNA - PC-3 [nTPM]":"6.2","Cell RNA - REH [nTPM]":"1.3","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"15.9","Cell RNA - RPTEC TERT1 [nTPM]":"13.5","Cell RNA - RT4 [nTPM]":"15.2","Cell RNA - SCLC-21H [nTPM]":"4.8","Cell RNA - SH-SY5Y [nTPM]":"3.3","Cell RNA - SiHa [nTPM]":"37.8","Cell RNA - SK-BR-3 [nTPM]":"28.9","Cell RNA - SK-MEL-30 [nTPM]":"7.6","Cell RNA - SuSa [nTPM]":"2.9","Cell RNA - T-47d [nTPM]":"13.5","Cell RNA - THP-1 [nTPM]":"3.1","Cell RNA - TIME [nTPM]":"0.7","Cell RNA - U-138 MG [nTPM]":"0.7","Cell RNA - U-2 OS [nTPM]":"3.9","Cell RNA - U-2197 [nTPM]":"9.5","Cell RNA - U-251 MG [nTPM]":"3.3","Cell RNA - U-266\/70 [nTPM]":"6.0","Cell RNA - U-266\/84 [nTPM]":"12.8","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"2.9","Cell RNA - U-937 [nTPM]":"5.9","Cell RNA - WM-115 [nTPM]":"2.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.1","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"1.2","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"3.1","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"1.1","Blood RNA - naive CD8 T-cell [nTPM]":"1.4","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"2.1","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"7.5","Brain RNA - basal ganglia [nTPM]":"7.9","Brain RNA - cerebellum [nTPM]":"7.8","Brain RNA - cerebral cortex [nTPM]":"7.8","Brain RNA - hippocampal formation [nTPM]":"7.3","Brain RNA - hypothalamus [nTPM]":"8.0","Brain RNA - medulla oblongata [nTPM]":"7.8","Brain RNA - midbrain [nTPM]":"7.8","Brain RNA - pons [nTPM]":"7.4","Brain RNA - spinal cord [nTPM]":"7.5","Brain RNA - thalamus [nTPM]":"8.0","Brain RNA - white matter [nTPM]":"7.8","Single Cell Type RNA - Adipocytes [nTPM]":"3.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.2","Single Cell Type RNA - Astrocytes [nTPM]":"23.5","Single Cell Type RNA - B-cells [nTPM]":"3.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Bipolar cells [nTPM]":"6.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"5.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.6","Single Cell Type RNA - dendritic cells [nTPM]":"3.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"63.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.8","Single Cell Type RNA - Early spermatids [nTPM]":"2.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.3","Single Cell Type RNA - Endothelial cells [nTPM]":"2.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.5","Single Cell Type RNA - Fibroblasts [nTPM]":"5.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"6.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.9","Single Cell Type RNA - Hepatocytes [nTPM]":"8.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.2","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.3","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"6.7","Single Cell Type RNA - Langerhans cells [nTPM]":"1.6","Single Cell Type RNA - Late spermatids [nTPM]":"2.8","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"5.9","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"1.3","Single Cell Type RNA - Muller glia cells [nTPM]":"9.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.4","Single Cell Type RNA - Paneth cells [nTPM]":"26.3","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"4.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"56.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.8","Single Cell Type RNA - Spermatocytes [nTPM]":"8.4","Single Cell Type RNA - Spermatogonia [nTPM]":"2.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.2","Single Cell Type RNA - T-cells [nTPM]":"4.0","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.0","Single Cell Type RNA - Urothelial cells [nTPM]":"9.0"},{"Gene":"SLC24A1","Gene synonym":["CSNB1D","HsT17412","KIAA0702","NCKX","NCKX1","RODX"],"Ensembl":"ENSG00000074621","Gene description":"Solute carrier family 24 member 1","Uniprot":["O60721"],"Chromosome":"15","Position":"65611366-65660995","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Calcium transport","Ion transport","Sensory transduction","Symport","Transport","Vision"],"Molecular function":null,"Disease involvement":["Congenital stationary night blindness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"34","RNA tissue specific nTPM":{"retina":"193.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Rod photoreceptor cells":"338.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"2.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039370"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA039370":"AB_10960279"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.33e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.0","Tissue RNA - adrenal gland [nTPM]":"3.0","Tissue RNA - amygdala [nTPM]":"2.4","Tissue RNA - appendix [nTPM]":"1.9","Tissue RNA - basal ganglia [nTPM]":"2.2","Tissue RNA - bone marrow [nTPM]":"1.8","Tissue RNA - breast [nTPM]":"4.9","Tissue RNA - cerebellum [nTPM]":"5.7","Tissue RNA - cerebral cortex [nTPM]":"2.7","Tissue RNA - cervix [nTPM]":"4.8","Tissue RNA - choroid plexus [nTPM]":"2.5","Tissue RNA - colon [nTPM]":"2.6","Tissue RNA - duodenum [nTPM]":"2.2","Tissue RNA - endometrium 1 [nTPM]":"3.8","Tissue RNA - epididymis [nTPM]":"4.7","Tissue RNA - esophagus [nTPM]":"2.4","Tissue RNA - fallopian tube [nTPM]":"5.1","Tissue RNA - gallbladder [nTPM]":"3.8","Tissue RNA - heart muscle [nTPM]":"1.6","Tissue RNA - hippocampal formation [nTPM]":"2.1","Tissue RNA - hypothalamus [nTPM]":"2.1","Tissue RNA - kidney [nTPM]":"5.1","Tissue RNA - liver [nTPM]":"2.9","Tissue RNA - lung [nTPM]":"3.1","Tissue RNA - lymph node [nTPM]":"3.3","Tissue RNA - medulla oblongata [nTPM]":"2.3","Tissue RNA - midbrain [nTPM]":"2.3","Tissue RNA - ovary [nTPM]":"5.4","Tissue RNA - pancreas [nTPM]":"2.9","Tissue RNA - parathyroid gland [nTPM]":"3.8","Tissue RNA - pituitary gland [nTPM]":"2.7","Tissue RNA - placenta [nTPM]":"3.6","Tissue RNA - pons [nTPM]":"2.3","Tissue RNA - prostate [nTPM]":"3.2","Tissue RNA - rectum [nTPM]":"2.4","Tissue RNA - retina [nTPM]":"193.5","Tissue RNA - salivary gland [nTPM]":"2.6","Tissue RNA - seminal vesicle [nTPM]":"3.1","Tissue RNA - skeletal muscle [nTPM]":"1.0","Tissue RNA - skin 1 [nTPM]":"5.1","Tissue RNA - small intestine [nTPM]":"3.0","Tissue RNA - smooth muscle [nTPM]":"2.9","Tissue RNA - spinal cord [nTPM]":"2.3","Tissue RNA - spleen [nTPM]":"3.9","Tissue RNA - stomach 1 [nTPM]":"2.5","Tissue RNA - testis [nTPM]":"4.1","Tissue RNA - thalamus [nTPM]":"2.1","Tissue RNA - thymus [nTPM]":"2.4","Tissue RNA - thyroid gland [nTPM]":"5.1","Tissue RNA - tongue [nTPM]":"1.3","Tissue RNA - tonsil [nTPM]":"1.8","Tissue RNA - urinary bladder [nTPM]":"3.0","Tissue RNA - vagina [nTPM]":"3.2","Tissue RNA - white matter [nTPM]":"2.5","Cell RNA - A-431 [nTPM]":"1.5","Cell RNA - A549 [nTPM]":"3.0","Cell RNA - AF22 [nTPM]":"3.2","Cell RNA - AN3-CA [nTPM]":"2.9","Cell RNA - ASC diff [nTPM]":"4.7","Cell RNA - ASC TERT1 [nTPM]":"7.9","Cell RNA - BEWO [nTPM]":"4.0","Cell RNA - BJ [nTPM]":"3.7","Cell RNA - BJ hTERT+ [nTPM]":"4.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.4","Cell RNA - CACO-2 [nTPM]":"1.4","Cell RNA - CAPAN-2 [nTPM]":"6.5","Cell RNA - Daudi [nTPM]":"2.1","Cell RNA - EFO-21 [nTPM]":"12.4","Cell RNA - fHDF\/TERT166 [nTPM]":"3.7","Cell RNA - GAMG [nTPM]":"1.3","Cell RNA - HaCaT [nTPM]":"4.1","Cell RNA - HAP1 [nTPM]":"3.9","Cell RNA - HBEC3-KT [nTPM]":"4.2","Cell RNA - HBF TERT88 [nTPM]":"2.1","Cell RNA - HDLM-2 [nTPM]":"2.2","Cell RNA - HEK 293 [nTPM]":"2.8","Cell RNA - HEL [nTPM]":"4.6","Cell RNA - HeLa [nTPM]":"2.5","Cell RNA - Hep G2 [nTPM]":"6.8","Cell RNA - HHSteC [nTPM]":"6.8","Cell RNA - HL-60 [nTPM]":"3.1","Cell RNA - HMC-1 [nTPM]":"6.0","Cell RNA - HSkMC [nTPM]":"6.7","Cell RNA - hTCEpi [nTPM]":"5.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.1","Cell RNA - hTERT-HME1 [nTPM]":"12.3","Cell RNA - hTERT-RPE1 [nTPM]":"5.1","Cell RNA - HUVEC TERT2 [nTPM]":"6.4","Cell RNA - JURKAT [nTPM]":"4.8","Cell RNA - K-562 [nTPM]":"5.0","Cell RNA - Karpas-707 [nTPM]":"7.0","Cell RNA - LHCN-M2 [nTPM]":"6.0","Cell RNA - MCF7 [nTPM]":"6.4","Cell RNA - MOLT-4 [nTPM]":"2.0","Cell RNA - NB-4 [nTPM]":"2.8","Cell RNA - NTERA-2 [nTPM]":"4.1","Cell RNA - OE19 [nTPM]":"13.5","Cell RNA - PC-3 [nTPM]":"1.2","Cell RNA - REH [nTPM]":"2.0","Cell RNA - RH-30 [nTPM]":"1.0","Cell RNA - RPMI-8226 [nTPM]":"1.4","Cell RNA - RPTEC TERT1 [nTPM]":"5.6","Cell RNA - RT4 [nTPM]":"6.0","Cell RNA - SCLC-21H [nTPM]":"1.5","Cell RNA - SH-SY5Y [nTPM]":"2.1","Cell RNA - SiHa [nTPM]":"1.0","Cell RNA - SK-BR-3 [nTPM]":"2.8","Cell RNA - SK-MEL-30 [nTPM]":"8.0","Cell RNA - SuSa [nTPM]":"4.4","Cell RNA - T-47d [nTPM]":"6.0","Cell RNA - THP-1 [nTPM]":"4.2","Cell RNA - TIME [nTPM]":"9.3","Cell RNA - U-138 MG [nTPM]":"3.7","Cell RNA - U-2 OS [nTPM]":"3.7","Cell RNA - U-2197 [nTPM]":"1.4","Cell RNA - U-251 MG [nTPM]":"2.6","Cell RNA - U-266\/70 [nTPM]":"2.8","Cell RNA - U-266\/84 [nTPM]":"5.5","Cell RNA - U-698 [nTPM]":"2.4","Cell RNA - U-87 MG [nTPM]":"3.9","Cell RNA - U-937 [nTPM]":"6.4","Cell RNA - WM-115 [nTPM]":"3.1","Blood RNA - basophil [nTPM]":"2.6","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"2.4","Brain RNA - basal ganglia [nTPM]":"2.2","Brain RNA - cerebellum [nTPM]":"5.7","Brain RNA - cerebral cortex [nTPM]":"2.7","Brain RNA - hippocampal formation [nTPM]":"2.1","Brain RNA - hypothalamus [nTPM]":"2.1","Brain RNA - medulla oblongata [nTPM]":"2.3","Brain RNA - midbrain [nTPM]":"2.3","Brain RNA - pons [nTPM]":"2.3","Brain RNA - spinal cord [nTPM]":"2.3","Brain RNA - thalamus [nTPM]":"2.1","Brain RNA - white matter [nTPM]":"2.5","Single Cell Type RNA - Adipocytes [nTPM]":"4.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.1","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"3.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"29.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.2","Single Cell Type RNA - dendritic cells [nTPM]":"1.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.5","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.4","Single Cell Type RNA - Endothelial cells [nTPM]":"15.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.7","Single Cell Type RNA - Fibroblasts [nTPM]":"2.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.9","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"4.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"1.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.9","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.5","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.1","Single Cell Type RNA - Langerhans cells [nTPM]":"1.6","Single Cell Type RNA - Late spermatids [nTPM]":"2.5","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"2.7","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"1.2","Single Cell Type RNA - Muller glia cells [nTPM]":"26.1","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.5","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"3.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"338.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.5","Single Cell Type RNA - Spermatocytes [nTPM]":"20.3","Single Cell Type RNA - Spermatogonia [nTPM]":"10.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - T-cells [nTPM]":"2.5","Single Cell Type RNA - Theca cells [nTPM]":"8.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.9"},{"Gene":"SLC24A4","Gene synonym":["NCKX4"],"Ensembl":"ENSG00000140090","Gene description":"Solute carrier family 24 member 4","Uniprot":["Q8NFF2"],"Chromosome":"14","Position":"92322581-92501481","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Calcium transport","Ion transport","Olfaction","Potassium transport","Sensory transduction","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Amelogenesis imperfecta","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"choroid plexus":"92.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Bipolar cells":"251.6","Cone photoreceptor cells":"200.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"0.5","melanoma":"0.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"11.1","intermediate monocyte":"14.7","non-classical monocyte":"11.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"monocytes":"14.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SCLC-21H":"1.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063206"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA063206":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"7.1","Tissue RNA - appendix [nTPM]":"1.4","Tissue RNA - basal ganglia [nTPM]":"10.3","Tissue RNA - bone marrow [nTPM]":"3.5","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"17.5","Tissue RNA - cerebral cortex [nTPM]":"8.1","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"92.6","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.6","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"7.2","Tissue RNA - hypothalamus [nTPM]":"5.3","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.8","Tissue RNA - lymph node [nTPM]":"1.2","Tissue RNA - medulla oblongata [nTPM]":"22.7","Tissue RNA - midbrain [nTPM]":"14.1","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.4","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"19.1","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"12.3","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.8","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"14.7","Tissue RNA - spleen [nTPM]":"2.7","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"1.1","Tissue RNA - thalamus [nTPM]":"16.5","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"1.0","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"12.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.7","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.3","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"11.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"14.7","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"3.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"1.5","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"11.6","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"2.7","Brain RNA - amygdala [nTPM]":"7.1","Brain RNA - basal ganglia [nTPM]":"10.3","Brain RNA - cerebellum [nTPM]":"17.5","Brain RNA - cerebral cortex [nTPM]":"8.1","Brain RNA - hippocampal formation [nTPM]":"7.2","Brain RNA - hypothalamus [nTPM]":"5.3","Brain RNA - medulla oblongata [nTPM]":"22.7","Brain RNA - midbrain [nTPM]":"14.1","Brain RNA - pons [nTPM]":"19.1","Brain RNA - spinal cord [nTPM]":"14.7","Brain RNA - thalamus [nTPM]":"16.5","Brain RNA - white matter [nTPM]":"12.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.9","Single Cell Type RNA - Astrocytes [nTPM]":"47.0","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"251.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"200.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"4.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"28.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"22.2","Single Cell Type RNA - Langerhans cells [nTPM]":"1.8","Single Cell Type RNA - Late spermatids [nTPM]":"5.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"16.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"44.3","Single Cell Type RNA - Muller glia cells [nTPM]":"4.1","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"1.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"SLC24A5","Gene synonym":["JSX","OCA6"],"Ensembl":"ENSG00000188467","Gene description":"Solute carrier family 24 member 5","Uniprot":["Q71RS6"],"Chromosome":"15","Position":"48120990-48142672","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Calcium transport","Ion transport","Potassium transport","Sensory transduction","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Albinism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"skin 1":"8.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Early spermatids":"20.7","Melanocytes":"76.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"162","RNA cancer specific FPKM":{"melanoma":"8.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"800","RNA cell line specific nTPM":{"SK-MEL-30":"251.8"},"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"hippocampal formation":"3.0","pons and medulla":"4.1","thalamus":"1.5"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-3"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.5","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.4","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"8.2","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"1.7","Tissue RNA - thalamus [nTPM]":"0.9","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"251.8","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.5","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.9","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"6.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"20.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"6.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"76.5","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SLC25A1","Gene synonym":["CTP","SLC20A3"],"Ensembl":"ENSG00000100075","Gene description":"Solute carrier family 25 member 1","Uniprot":["P53007"],"Chromosome":"22","Position":"19175581-19178739","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"197.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"221.1","Proximal enterocytes":"304.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"101.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-2"},"Tissue RNA - adipose tissue [nTPM]":"113.3","Tissue RNA - adrenal gland [nTPM]":"76.3","Tissue RNA - amygdala [nTPM]":"45.8","Tissue RNA - appendix [nTPM]":"22.3","Tissue RNA - basal ganglia [nTPM]":"46.9","Tissue RNA - bone marrow [nTPM]":"14.2","Tissue RNA - breast [nTPM]":"90.3","Tissue RNA - cerebellum [nTPM]":"49.5","Tissue RNA - cerebral cortex [nTPM]":"58.6","Tissue RNA - cervix [nTPM]":"43.5","Tissue RNA - choroid plexus [nTPM]":"47.6","Tissue RNA - colon [nTPM]":"63.9","Tissue RNA - duodenum [nTPM]":"114.1","Tissue RNA - endometrium 1 [nTPM]":"40.0","Tissue RNA - epididymis [nTPM]":"16.2","Tissue RNA - esophagus [nTPM]":"59.2","Tissue RNA - fallopian tube [nTPM]":"34.7","Tissue RNA - gallbladder [nTPM]":"21.5","Tissue RNA - heart muscle [nTPM]":"27.3","Tissue RNA - hippocampal formation [nTPM]":"41.5","Tissue RNA - hypothalamus [nTPM]":"65.8","Tissue RNA - kidney [nTPM]":"86.8","Tissue RNA - liver [nTPM]":"197.7","Tissue RNA - lung [nTPM]":"33.6","Tissue RNA - lymph node [nTPM]":"21.4","Tissue RNA - medulla oblongata [nTPM]":"61.0","Tissue RNA - midbrain [nTPM]":"58.3","Tissue RNA - ovary [nTPM]":"43.6","Tissue RNA - pancreas [nTPM]":"54.8","Tissue RNA - parathyroid gland [nTPM]":"33.1","Tissue RNA - pituitary gland [nTPM]":"39.3","Tissue RNA - placenta [nTPM]":"27.4","Tissue RNA - pons [nTPM]":"73.0","Tissue RNA - prostate [nTPM]":"53.9","Tissue RNA - rectum [nTPM]":"33.9","Tissue RNA - retina [nTPM]":"5.6","Tissue RNA - salivary gland [nTPM]":"39.5","Tissue RNA - seminal vesicle [nTPM]":"30.0","Tissue RNA - skeletal muscle [nTPM]":"17.3","Tissue RNA - skin 1 [nTPM]":"49.1","Tissue RNA - small intestine [nTPM]":"92.4","Tissue RNA - smooth muscle [nTPM]":"21.0","Tissue RNA - spinal cord [nTPM]":"49.4","Tissue RNA - spleen [nTPM]":"31.4","Tissue RNA - stomach 1 [nTPM]":"52.9","Tissue RNA - testis [nTPM]":"36.3","Tissue RNA - thalamus [nTPM]":"51.8","Tissue RNA - thymus [nTPM]":"16.3","Tissue RNA - thyroid gland [nTPM]":"46.1","Tissue RNA - tongue [nTPM]":"7.7","Tissue RNA - tonsil [nTPM]":"25.5","Tissue RNA - urinary bladder [nTPM]":"43.9","Tissue RNA - vagina [nTPM]":"40.8","Tissue RNA - white matter [nTPM]":"55.2","Cell RNA - A-431 [nTPM]":"111.9","Cell RNA - A549 [nTPM]":"114.3","Cell RNA - AF22 [nTPM]":"85.9","Cell RNA - AN3-CA [nTPM]":"73.6","Cell RNA - ASC diff [nTPM]":"209.1","Cell RNA - ASC TERT1 [nTPM]":"102.5","Cell RNA - BEWO [nTPM]":"91.2","Cell RNA - BJ [nTPM]":"77.5","Cell RNA - BJ hTERT+ [nTPM]":"96.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"65.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"90.4","Cell RNA - CACO-2 [nTPM]":"136.4","Cell RNA - CAPAN-2 [nTPM]":"77.2","Cell RNA - Daudi [nTPM]":"66.9","Cell RNA - EFO-21 [nTPM]":"38.8","Cell RNA - fHDF\/TERT166 [nTPM]":"110.5","Cell RNA - GAMG [nTPM]":"70.5","Cell RNA - HaCaT [nTPM]":"95.4","Cell RNA - HAP1 [nTPM]":"82.9","Cell RNA - HBEC3-KT [nTPM]":"138.1","Cell RNA - HBF TERT88 [nTPM]":"37.2","Cell RNA - HDLM-2 [nTPM]":"59.6","Cell RNA - HEK 293 [nTPM]":"164.1","Cell RNA - HEL [nTPM]":"35.5","Cell RNA - HeLa [nTPM]":"97.7","Cell RNA - Hep G2 [nTPM]":"278.4","Cell RNA - HHSteC [nTPM]":"148.2","Cell RNA - HL-60 [nTPM]":"67.3","Cell RNA - HMC-1 [nTPM]":"107.5","Cell RNA - HSkMC [nTPM]":"145.1","Cell RNA - hTCEpi [nTPM]":"81.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"75.7","Cell RNA - hTERT-HME1 [nTPM]":"58.4","Cell RNA - hTERT-RPE1 [nTPM]":"73.3","Cell RNA - HUVEC TERT2 [nTPM]":"62.8","Cell RNA - JURKAT [nTPM]":"53.4","Cell RNA - K-562 [nTPM]":"184.6","Cell RNA - Karpas-707 [nTPM]":"61.9","Cell RNA - LHCN-M2 [nTPM]":"74.7","Cell RNA - MCF7 [nTPM]":"288.1","Cell RNA - MOLT-4 [nTPM]":"37.0","Cell RNA - NB-4 [nTPM]":"80.8","Cell RNA - NTERA-2 [nTPM]":"57.5","Cell RNA - OE19 [nTPM]":"173.5","Cell RNA - PC-3 [nTPM]":"70.0","Cell RNA - REH [nTPM]":"70.4","Cell RNA - RH-30 [nTPM]":"44.6","Cell RNA - RPMI-8226 [nTPM]":"29.9","Cell RNA - RPTEC TERT1 [nTPM]":"196.2","Cell RNA - RT4 [nTPM]":"135.8","Cell RNA - SCLC-21H [nTPM]":"55.5","Cell RNA - SH-SY5Y [nTPM]":"71.2","Cell RNA - SiHa [nTPM]":"83.1","Cell RNA - SK-BR-3 [nTPM]":"163.0","Cell RNA - SK-MEL-30 [nTPM]":"48.6","Cell RNA - SuSa [nTPM]":"52.6","Cell RNA - T-47d [nTPM]":"122.6","Cell RNA - THP-1 [nTPM]":"171.7","Cell RNA - TIME [nTPM]":"63.6","Cell RNA - U-138 MG [nTPM]":"80.3","Cell RNA - U-2 OS [nTPM]":"69.3","Cell RNA - U-2197 [nTPM]":"62.0","Cell RNA - U-251 MG [nTPM]":"53.2","Cell RNA - U-266\/70 [nTPM]":"78.2","Cell RNA - U-266\/84 [nTPM]":"39.9","Cell RNA - U-698 [nTPM]":"35.4","Cell RNA - U-87 MG [nTPM]":"82.5","Cell RNA - U-937 [nTPM]":"31.5","Cell RNA - WM-115 [nTPM]":"41.4","Blood RNA - basophil [nTPM]":"11.6","Blood RNA - classical monocyte [nTPM]":"15.7","Blood RNA - eosinophil [nTPM]":"101.9","Blood RNA - gdT-cell [nTPM]":"16.6","Blood RNA - intermediate monocyte [nTPM]":"17.9","Blood RNA - MAIT T-cell [nTPM]":"10.6","Blood RNA - memory B-cell [nTPM]":"33.3","Blood RNA - memory CD4 T-cell [nTPM]":"18.7","Blood RNA - memory CD8 T-cell [nTPM]":"18.2","Blood RNA - myeloid DC [nTPM]":"13.7","Blood RNA - naive B-cell [nTPM]":"43.5","Blood RNA - naive CD4 T-cell [nTPM]":"16.7","Blood RNA - naive CD8 T-cell [nTPM]":"14.3","Blood RNA - neutrophil [nTPM]":"8.1","Blood RNA - NK-cell [nTPM]":"13.7","Blood RNA - non-classical monocyte [nTPM]":"23.8","Blood RNA - plasmacytoid DC [nTPM]":"10.5","Blood RNA - T-reg [nTPM]":"19.6","Blood RNA - total PBMC [nTPM]":"10.6","Brain RNA - amygdala [nTPM]":"45.8","Brain RNA - basal ganglia [nTPM]":"46.9","Brain RNA - cerebellum [nTPM]":"49.5","Brain RNA - cerebral cortex [nTPM]":"58.6","Brain RNA - hippocampal formation [nTPM]":"41.5","Brain RNA - hypothalamus [nTPM]":"65.8","Brain RNA - medulla oblongata [nTPM]":"61.0","Brain RNA - midbrain [nTPM]":"58.3","Brain RNA - pons [nTPM]":"73.0","Brain RNA - spinal cord [nTPM]":"49.4","Brain RNA - thalamus [nTPM]":"51.8","Brain RNA - white matter [nTPM]":"55.2","Single Cell Type RNA - Adipocytes [nTPM]":"18.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.9","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"35.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"22.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.9","Single Cell Type RNA - Bipolar cells [nTPM]":"7.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"44.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"41.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"17.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"135.6","Single Cell Type RNA - dendritic cells [nTPM]":"18.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"178.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"50.9","Single Cell Type RNA - Ductal cells [nTPM]":"33.5","Single Cell Type RNA - Early spermatids [nTPM]":"30.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"41.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"37.0","Single Cell Type RNA - Endothelial cells [nTPM]":"16.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"41.0","Single Cell Type RNA - Erythroid cells [nTPM]":"21.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"45.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"139.5","Single Cell Type RNA - Fibroblasts [nTPM]":"27.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"50.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"83.7","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"67.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.4","Single Cell Type RNA - Hepatocytes [nTPM]":"221.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"47.5","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"107.3","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"30.5","Single Cell Type RNA - Langerhans cells [nTPM]":"18.2","Single Cell Type RNA - Late spermatids [nTPM]":"98.8","Single Cell Type RNA - Leydig cells [nTPM]":"28.9","Single Cell Type RNA - Macrophages [nTPM]":"32.6","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"29.6","Single Cell Type RNA - Muller glia cells [nTPM]":"27.7","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"39.7","Single Cell Type RNA - Paneth cells [nTPM]":"128.1","Single Cell Type RNA - Peritubular cells [nTPM]":"29.3","Single Cell Type RNA - Plasma cells [nTPM]":"38.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"28.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"304.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"127.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"37.8","Single Cell Type RNA - Spermatocytes [nTPM]":"15.3","Single Cell Type RNA - Spermatogonia [nTPM]":"29.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"60.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"30.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"127.7","Single Cell Type RNA - T-cells [nTPM]":"24.6","Single Cell Type RNA - Theca cells [nTPM]":"55.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"108.3","Single Cell Type RNA - Urothelial cells [nTPM]":"30.4"},{"Gene":"SLC25A11","Gene synonym":["OGC","SLC20A4"],"Ensembl":"ENSG00000108528","Gene description":"Solute carrier family 25 member 11","Uniprot":["Q02978"],"Chromosome":"17","Position":"4937130-4940053","Protein class":["Disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"heart muscle":"233.6","skeletal muscle":"314.5","tongue":"450.4"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021167"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"25000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA021167":"AB_1857021"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.41e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.84e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Tissue RNA - adipose tissue [nTPM]":"35.6","Tissue RNA - adrenal gland [nTPM]":"52.5","Tissue RNA - amygdala [nTPM]":"69.2","Tissue RNA - appendix [nTPM]":"33.8","Tissue RNA - basal ganglia [nTPM]":"70.7","Tissue RNA - bone marrow [nTPM]":"31.7","Tissue RNA - breast [nTPM]":"32.0","Tissue RNA - cerebellum [nTPM]":"77.7","Tissue RNA - cerebral cortex [nTPM]":"79.8","Tissue RNA - cervix [nTPM]":"35.3","Tissue RNA - choroid plexus [nTPM]":"70.8","Tissue RNA - colon [nTPM]":"46.7","Tissue RNA - duodenum [nTPM]":"47.5","Tissue RNA - endometrium 1 [nTPM]":"36.7","Tissue RNA - epididymis [nTPM]":"22.1","Tissue RNA - esophagus [nTPM]":"50.5","Tissue RNA - fallopian tube [nTPM]":"41.6","Tissue RNA - gallbladder [nTPM]":"30.7","Tissue RNA - heart muscle [nTPM]":"233.6","Tissue RNA - hippocampal formation [nTPM]":"76.8","Tissue RNA - hypothalamus [nTPM]":"73.6","Tissue RNA - kidney [nTPM]":"66.6","Tissue RNA - liver [nTPM]":"66.7","Tissue RNA - lung [nTPM]":"30.0","Tissue RNA - lymph node [nTPM]":"40.7","Tissue RNA - medulla oblongata [nTPM]":"69.2","Tissue RNA - midbrain [nTPM]":"72.7","Tissue RNA - ovary [nTPM]":"30.7","Tissue RNA - pancreas [nTPM]":"27.9","Tissue RNA - parathyroid gland [nTPM]":"70.8","Tissue RNA - pituitary gland [nTPM]":"36.4","Tissue RNA - placenta [nTPM]":"27.6","Tissue RNA - pons [nTPM]":"69.6","Tissue RNA - prostate [nTPM]":"34.0","Tissue RNA - rectum [nTPM]":"36.1","Tissue RNA - retina [nTPM]":"23.2","Tissue RNA - salivary gland [nTPM]":"41.6","Tissue RNA - seminal vesicle [nTPM]":"38.4","Tissue RNA - skeletal muscle [nTPM]":"314.5","Tissue RNA - skin 1 [nTPM]":"48.7","Tissue RNA - small intestine [nTPM]":"40.2","Tissue RNA - smooth muscle [nTPM]":"33.4","Tissue RNA - spinal cord [nTPM]":"70.2","Tissue RNA - spleen [nTPM]":"37.5","Tissue RNA - stomach 1 [nTPM]":"39.9","Tissue RNA - testis [nTPM]":"10.9","Tissue RNA - thalamus [nTPM]":"77.0","Tissue RNA - thymus [nTPM]":"45.1","Tissue RNA - thyroid gland [nTPM]":"38.5","Tissue RNA - tongue [nTPM]":"450.4","Tissue RNA - tonsil [nTPM]":"33.9","Tissue RNA - urinary bladder [nTPM]":"38.5","Tissue RNA - vagina [nTPM]":"33.3","Tissue RNA - white matter [nTPM]":"71.5","Cell RNA - A-431 [nTPM]":"51.1","Cell RNA - A549 [nTPM]":"134.6","Cell RNA - AF22 [nTPM]":"67.3","Cell RNA - AN3-CA [nTPM]":"66.3","Cell RNA - ASC diff [nTPM]":"64.7","Cell RNA - ASC TERT1 [nTPM]":"39.9","Cell RNA - BEWO [nTPM]":"47.3","Cell RNA - BJ [nTPM]":"56.2","Cell RNA - BJ hTERT+ [nTPM]":"57.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"96.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"79.3","Cell RNA - CACO-2 [nTPM]":"85.1","Cell RNA - CAPAN-2 [nTPM]":"24.7","Cell RNA - Daudi [nTPM]":"78.3","Cell RNA - EFO-21 [nTPM]":"74.5","Cell RNA - fHDF\/TERT166 [nTPM]":"55.3","Cell RNA - GAMG [nTPM]":"46.8","Cell RNA - HaCaT [nTPM]":"99.6","Cell RNA - HAP1 [nTPM]":"88.1","Cell RNA - HBEC3-KT [nTPM]":"101.5","Cell RNA - HBF TERT88 [nTPM]":"37.8","Cell RNA - HDLM-2 [nTPM]":"99.6","Cell RNA - HEK 293 [nTPM]":"113.8","Cell RNA - HEL [nTPM]":"86.4","Cell RNA - HeLa [nTPM]":"70.9","Cell RNA - Hep G2 [nTPM]":"74.5","Cell RNA - HHSteC [nTPM]":"66.0","Cell RNA - HL-60 [nTPM]":"37.6","Cell RNA - HMC-1 [nTPM]":"100.7","Cell RNA - HSkMC [nTPM]":"57.7","Cell RNA - hTCEpi [nTPM]":"65.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"85.4","Cell RNA - hTERT-HME1 [nTPM]":"71.7","Cell RNA - hTERT-RPE1 [nTPM]":"46.7","Cell RNA - HUVEC TERT2 [nTPM]":"67.8","Cell RNA - JURKAT [nTPM]":"83.2","Cell RNA - K-562 [nTPM]":"38.7","Cell RNA - Karpas-707 [nTPM]":"74.1","Cell RNA - LHCN-M2 [nTPM]":"82.7","Cell RNA - MCF7 [nTPM]":"91.2","Cell RNA - MOLT-4 [nTPM]":"121.6","Cell RNA - NB-4 [nTPM]":"38.3","Cell RNA - NTERA-2 [nTPM]":"35.6","Cell RNA - OE19 [nTPM]":"56.1","Cell RNA - PC-3 [nTPM]":"89.6","Cell RNA - REH [nTPM]":"108.6","Cell RNA - RH-30 [nTPM]":"41.4","Cell RNA - RPMI-8226 [nTPM]":"71.0","Cell RNA - RPTEC TERT1 [nTPM]":"74.8","Cell RNA - RT4 [nTPM]":"52.6","Cell RNA - SCLC-21H [nTPM]":"59.9","Cell RNA - SH-SY5Y [nTPM]":"62.1","Cell RNA - SiHa [nTPM]":"70.9","Cell RNA - SK-BR-3 [nTPM]":"79.0","Cell RNA - SK-MEL-30 [nTPM]":"65.2","Cell RNA - SuSa [nTPM]":"33.6","Cell RNA - T-47d [nTPM]":"73.3","Cell RNA - THP-1 [nTPM]":"58.7","Cell RNA - TIME [nTPM]":"46.0","Cell RNA - U-138 MG [nTPM]":"43.0","Cell RNA - U-2 OS [nTPM]":"28.1","Cell RNA - U-2197 [nTPM]":"58.8","Cell RNA - U-251 MG [nTPM]":"109.7","Cell RNA - U-266\/70 [nTPM]":"39.3","Cell RNA - U-266\/84 [nTPM]":"25.4","Cell RNA - U-698 [nTPM]":"30.7","Cell RNA - U-87 MG [nTPM]":"84.8","Cell RNA - U-937 [nTPM]":"62.6","Cell RNA - WM-115 [nTPM]":"108.4","Blood RNA - basophil [nTPM]":"126.0","Blood RNA - classical monocyte [nTPM]":"170.3","Blood RNA - eosinophil [nTPM]":"132.3","Blood RNA - gdT-cell [nTPM]":"98.8","Blood RNA - intermediate monocyte [nTPM]":"176.8","Blood RNA - MAIT T-cell [nTPM]":"90.8","Blood RNA - memory B-cell [nTPM]":"87.5","Blood RNA - memory CD4 T-cell [nTPM]":"75.1","Blood RNA - memory CD8 T-cell [nTPM]":"87.8","Blood RNA - myeloid DC [nTPM]":"160.4","Blood RNA - naive B-cell [nTPM]":"74.3","Blood RNA - naive CD4 T-cell [nTPM]":"74.1","Blood RNA - naive CD8 T-cell [nTPM]":"81.2","Blood RNA - neutrophil [nTPM]":"111.8","Blood RNA - NK-cell [nTPM]":"151.6","Blood RNA - non-classical monocyte [nTPM]":"165.1","Blood RNA - plasmacytoid DC [nTPM]":"107.0","Blood RNA - T-reg [nTPM]":"97.3","Blood RNA - total PBMC [nTPM]":"186.2","Brain RNA - amygdala [nTPM]":"69.2","Brain RNA - basal ganglia [nTPM]":"70.7","Brain RNA - cerebellum [nTPM]":"77.7","Brain RNA - cerebral cortex [nTPM]":"79.8","Brain RNA - hippocampal formation [nTPM]":"76.8","Brain RNA - hypothalamus [nTPM]":"73.6","Brain RNA - medulla oblongata [nTPM]":"69.2","Brain RNA - midbrain [nTPM]":"72.7","Brain RNA - pons [nTPM]":"69.6","Brain RNA - spinal cord [nTPM]":"70.2","Brain RNA - thalamus [nTPM]":"77.0","Brain RNA - white matter [nTPM]":"71.5","Single Cell Type RNA - Adipocytes [nTPM]":"39.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.3","Single Cell Type RNA - Astrocytes [nTPM]":"12.7","Single Cell Type RNA - B-cells [nTPM]":"32.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"38.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"47.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"92.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.6","Single Cell Type RNA - Bipolar cells [nTPM]":"60.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"47.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"51.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"150.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"51.5","Single Cell Type RNA - Club cells [nTPM]":"40.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"66.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"132.2","Single Cell Type RNA - dendritic cells [nTPM]":"39.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"67.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"185.9","Single Cell Type RNA - Ductal cells [nTPM]":"60.7","Single Cell Type RNA - Early spermatids [nTPM]":"15.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"30.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.7","Single Cell Type RNA - Endothelial cells [nTPM]":"41.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"27.6","Single Cell Type RNA - Erythroid cells [nTPM]":"50.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"53.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"138.7","Single Cell Type RNA - Fibroblasts [nTPM]":"40.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"30.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"28.2","Single Cell Type RNA - granulocytes [nTPM]":"39.3","Single Cell Type RNA - Granulosa cells [nTPM]":"45.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"33.5","Single Cell Type RNA - Hepatocytes [nTPM]":"61.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"109.1","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"51.6","Single Cell Type RNA - Ionocytes [nTPM]":"99.7","Single Cell Type RNA - Kupffer cells [nTPM]":"45.3","Single Cell Type RNA - Langerhans cells [nTPM]":"44.4","Single Cell Type RNA - Late spermatids [nTPM]":"19.6","Single Cell Type RNA - Leydig cells [nTPM]":"30.4","Single Cell Type RNA - Macrophages [nTPM]":"56.2","Single Cell Type RNA - Melanocytes [nTPM]":"51.6","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"106.9","Single Cell Type RNA - Muller glia cells [nTPM]":"59.2","Single Cell Type RNA - NK-cells [nTPM]":"47.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"47.4","Single Cell Type RNA - Paneth cells [nTPM]":"58.7","Single Cell Type RNA - Peritubular cells [nTPM]":"38.4","Single Cell Type RNA - Plasma cells [nTPM]":"45.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"43.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"99.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"202.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"26.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"56.0","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"43.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"48.4","Single Cell Type RNA - Spermatocytes [nTPM]":"15.1","Single Cell Type RNA - Spermatogonia [nTPM]":"31.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"46.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"44.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"102.5","Single Cell Type RNA - T-cells [nTPM]":"38.4","Single Cell Type RNA - Theca cells [nTPM]":"57.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"88.3","Single Cell Type RNA - Urothelial cells [nTPM]":"42.1"},{"Gene":"SLC25A12","Gene synonym":["Aralar"],"Ensembl":"ENSG00000115840","Gene description":"Solute carrier family 25 member 12","Uniprot":["O75746"],"Chromosome":"2","Position":"171783405-171999859","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"97.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"97.7","Excitatory neurons":"148.5","Inhibitory neurons":"175.2","Oligodendrocyte precursor cells":"111.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035333","HPA035334"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nuclear speckles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9100","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA035333":"AB_10603028","HPA035334":"AB_2674577"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.86e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.91e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.64e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Tissue RNA - adipose tissue [nTPM]":"11.1","Tissue RNA - adrenal gland [nTPM]":"11.5","Tissue RNA - amygdala [nTPM]":"8.5","Tissue RNA - appendix [nTPM]":"4.0","Tissue RNA - basal ganglia [nTPM]":"9.0","Tissue RNA - bone marrow [nTPM]":"2.8","Tissue RNA - breast [nTPM]":"11.6","Tissue RNA - cerebellum [nTPM]":"9.3","Tissue RNA - cerebral cortex [nTPM]":"12.3","Tissue RNA - cervix [nTPM]":"11.5","Tissue RNA - choroid plexus [nTPM]":"6.1","Tissue RNA - colon [nTPM]":"25.2","Tissue RNA - duodenum [nTPM]":"2.2","Tissue RNA - endometrium 1 [nTPM]":"13.4","Tissue RNA - epididymis [nTPM]":"4.3","Tissue RNA - esophagus [nTPM]":"12.7","Tissue RNA - fallopian tube [nTPM]":"11.7","Tissue RNA - gallbladder [nTPM]":"3.7","Tissue RNA - heart muscle [nTPM]":"62.7","Tissue RNA - hippocampal formation [nTPM]":"8.9","Tissue RNA - hypothalamus [nTPM]":"9.0","Tissue RNA - kidney [nTPM]":"13.4","Tissue RNA - liver [nTPM]":"1.8","Tissue RNA - lung [nTPM]":"7.1","Tissue RNA - lymph node [nTPM]":"4.4","Tissue RNA - medulla oblongata [nTPM]":"6.9","Tissue RNA - midbrain [nTPM]":"6.7","Tissue RNA - ovary [nTPM]":"14.5","Tissue RNA - pancreas [nTPM]":"3.9","Tissue RNA - parathyroid gland [nTPM]":"12.0","Tissue RNA - pituitary gland [nTPM]":"17.1","Tissue RNA - placenta [nTPM]":"3.2","Tissue RNA - pons [nTPM]":"6.8","Tissue RNA - prostate [nTPM]":"13.7","Tissue RNA - rectum [nTPM]":"6.1","Tissue RNA - retina [nTPM]":"15.8","Tissue RNA - salivary gland [nTPM]":"16.8","Tissue RNA - seminal vesicle [nTPM]":"9.5","Tissue RNA - skeletal muscle [nTPM]":"97.0","Tissue RNA - skin 1 [nTPM]":"14.5","Tissue RNA - small intestine [nTPM]":"10.7","Tissue RNA - smooth muscle [nTPM]":"8.5","Tissue RNA - spinal cord [nTPM]":"5.8","Tissue RNA - spleen [nTPM]":"8.9","Tissue RNA - stomach 1 [nTPM]":"16.4","Tissue RNA - testis [nTPM]":"6.1","Tissue RNA - thalamus [nTPM]":"7.4","Tissue RNA - thymus [nTPM]":"5.6","Tissue RNA - thyroid gland [nTPM]":"15.1","Tissue RNA - tongue [nTPM]":"51.1","Tissue RNA - tonsil [nTPM]":"5.2","Tissue RNA - urinary bladder [nTPM]":"16.2","Tissue RNA - vagina [nTPM]":"12.4","Tissue RNA - white matter [nTPM]":"8.4","Cell RNA - A-431 [nTPM]":"4.9","Cell RNA - A549 [nTPM]":"3.0","Cell RNA - AF22 [nTPM]":"4.2","Cell RNA - AN3-CA [nTPM]":"8.0","Cell RNA - ASC diff [nTPM]":"9.5","Cell RNA - ASC TERT1 [nTPM]":"11.7","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"5.3","Cell RNA - BJ hTERT+ [nTPM]":"11.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.3","Cell RNA - CACO-2 [nTPM]":"2.2","Cell RNA - CAPAN-2 [nTPM]":"3.2","Cell RNA - Daudi [nTPM]":"14.5","Cell RNA - EFO-21 [nTPM]":"2.6","Cell RNA - fHDF\/TERT166 [nTPM]":"7.5","Cell RNA - GAMG [nTPM]":"4.3","Cell RNA - HaCaT [nTPM]":"4.3","Cell RNA - HAP1 [nTPM]":"7.9","Cell RNA - HBEC3-KT [nTPM]":"8.5","Cell RNA - HBF TERT88 [nTPM]":"10.7","Cell RNA - HDLM-2 [nTPM]":"6.3","Cell RNA - HEK 293 [nTPM]":"10.4","Cell RNA - HEL [nTPM]":"6.9","Cell RNA - HeLa [nTPM]":"4.4","Cell RNA - Hep G2 [nTPM]":"5.5","Cell RNA - HHSteC [nTPM]":"3.8","Cell RNA - HL-60 [nTPM]":"14.8","Cell RNA - HMC-1 [nTPM]":"4.9","Cell RNA - HSkMC [nTPM]":"12.6","Cell RNA - hTCEpi [nTPM]":"7.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.0","Cell RNA - hTERT-HME1 [nTPM]":"2.3","Cell RNA - hTERT-RPE1 [nTPM]":"4.1","Cell RNA - HUVEC TERT2 [nTPM]":"8.0","Cell RNA - JURKAT [nTPM]":"7.0","Cell RNA - K-562 [nTPM]":"5.0","Cell RNA - Karpas-707 [nTPM]":"5.2","Cell RNA - LHCN-M2 [nTPM]":"4.4","Cell RNA - MCF7 [nTPM]":"3.2","Cell RNA - MOLT-4 [nTPM]":"9.7","Cell RNA - NB-4 [nTPM]":"6.5","Cell RNA - NTERA-2 [nTPM]":"3.0","Cell RNA - OE19 [nTPM]":"3.8","Cell RNA - PC-3 [nTPM]":"4.7","Cell RNA - REH [nTPM]":"9.6","Cell RNA - RH-30 [nTPM]":"4.7","Cell RNA - RPMI-8226 [nTPM]":"7.4","Cell RNA - RPTEC TERT1 [nTPM]":"8.0","Cell RNA - RT4 [nTPM]":"4.5","Cell RNA - SCLC-21H [nTPM]":"5.1","Cell RNA - SH-SY5Y [nTPM]":"1.6","Cell RNA - SiHa [nTPM]":"2.6","Cell RNA - SK-BR-3 [nTPM]":"8.5","Cell RNA - SK-MEL-30 [nTPM]":"4.0","Cell RNA - SuSa [nTPM]":"2.5","Cell RNA - T-47d [nTPM]":"2.8","Cell RNA - THP-1 [nTPM]":"3.1","Cell RNA - TIME [nTPM]":"6.4","Cell RNA - U-138 MG [nTPM]":"6.2","Cell RNA - U-2 OS [nTPM]":"2.0","Cell RNA - U-2197 [nTPM]":"6.0","Cell RNA - U-251 MG [nTPM]":"3.2","Cell RNA - U-266\/70 [nTPM]":"8.8","Cell RNA - U-266\/84 [nTPM]":"4.2","Cell RNA - U-698 [nTPM]":"13.6","Cell RNA - U-87 MG [nTPM]":"9.1","Cell RNA - U-937 [nTPM]":"7.5","Cell RNA - WM-115 [nTPM]":"2.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.9","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.9","Blood RNA - non-classical monocyte [nTPM]":"0.7","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"8.5","Brain RNA - basal ganglia [nTPM]":"9.0","Brain RNA - cerebellum [nTPM]":"9.3","Brain RNA - cerebral cortex [nTPM]":"12.3","Brain RNA - hippocampal formation [nTPM]":"8.9","Brain RNA - hypothalamus [nTPM]":"9.0","Brain RNA - medulla oblongata [nTPM]":"6.9","Brain RNA - midbrain [nTPM]":"6.7","Brain RNA - pons [nTPM]":"6.8","Brain RNA - spinal cord [nTPM]":"5.8","Brain RNA - thalamus [nTPM]":"7.4","Brain RNA - white matter [nTPM]":"8.4","Single Cell Type RNA - Adipocytes [nTPM]":"9.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.8","Single Cell Type RNA - Astrocytes [nTPM]":"71.2","Single Cell Type RNA - B-cells [nTPM]":"11.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.9","Single Cell Type RNA - Bipolar cells [nTPM]":"25.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"97.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"18.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.5","Single Cell Type RNA - dendritic cells [nTPM]":"10.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"1.7","Single Cell Type RNA - Early spermatids [nTPM]":"3.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.3","Single Cell Type RNA - Endothelial cells [nTPM]":"8.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.4","Single Cell Type RNA - Erythroid cells [nTPM]":"6.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"148.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.8","Single Cell Type RNA - Fibroblasts [nTPM]":"15.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.1","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"7.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.5","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"175.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.1","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"8.4","Single Cell Type RNA - Langerhans cells [nTPM]":"5.4","Single Cell Type RNA - Late spermatids [nTPM]":"2.1","Single Cell Type RNA - Leydig cells [nTPM]":"12.5","Single Cell Type RNA - Macrophages [nTPM]":"7.2","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"25.3","Single Cell Type RNA - monocytes [nTPM]":"9.7","Single Cell Type RNA - Muller glia cells [nTPM]":"19.8","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"111.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"44.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.0","Single Cell Type RNA - Paneth cells [nTPM]":"4.7","Single Cell Type RNA - Peritubular cells [nTPM]":"24.5","Single Cell Type RNA - Plasma cells [nTPM]":"19.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"25.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.6","Single Cell Type RNA - Spermatocytes [nTPM]":"7.8","Single Cell Type RNA - Spermatogonia [nTPM]":"9.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - T-cells [nTPM]":"15.0","Single Cell Type RNA - Theca cells [nTPM]":"11.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.6","Single Cell Type RNA - Urothelial cells [nTPM]":"8.3"},{"Gene":"SLC25A13","Gene synonym":["ARALAR2","CITRIN","CTLN2"],"Ensembl":"ENSG00000004864","Gene description":"Solute carrier family 25 member 13","Uniprot":["Q9UJS0"],"Chromosome":"7","Position":"96120220-96322147","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Intrahepatic cholestasis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"liver":"150.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"153.4","Oligodendrocytes":"439.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018997"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"21000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA018997":"AB_1857023"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.14e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.2","Tissue RNA - adrenal gland [nTPM]":"14.3","Tissue RNA - amygdala [nTPM]":"7.0","Tissue RNA - appendix [nTPM]":"8.9","Tissue RNA - basal ganglia [nTPM]":"13.7","Tissue RNA - bone marrow [nTPM]":"8.0","Tissue RNA - breast [nTPM]":"10.3","Tissue RNA - cerebellum [nTPM]":"13.7","Tissue RNA - cerebral cortex [nTPM]":"10.0","Tissue RNA - cervix [nTPM]":"8.0","Tissue RNA - choroid plexus [nTPM]":"15.1","Tissue RNA - colon [nTPM]":"16.3","Tissue RNA - duodenum [nTPM]":"16.0","Tissue RNA - endometrium 1 [nTPM]":"7.6","Tissue RNA - epididymis [nTPM]":"10.2","Tissue RNA - esophagus [nTPM]":"9.6","Tissue RNA - fallopian tube [nTPM]":"9.5","Tissue RNA - gallbladder [nTPM]":"9.9","Tissue RNA - heart muscle [nTPM]":"6.6","Tissue RNA - hippocampal formation [nTPM]":"6.7","Tissue RNA - hypothalamus [nTPM]":"9.9","Tissue RNA - kidney [nTPM]":"32.3","Tissue RNA - liver [nTPM]":"150.1","Tissue RNA - lung [nTPM]":"7.9","Tissue RNA - lymph node [nTPM]":"7.1","Tissue RNA - medulla oblongata [nTPM]":"13.6","Tissue RNA - midbrain [nTPM]":"12.2","Tissue RNA - ovary [nTPM]":"7.8","Tissue RNA - pancreas [nTPM]":"9.6","Tissue RNA - parathyroid gland [nTPM]":"13.8","Tissue RNA - pituitary gland [nTPM]":"8.3","Tissue RNA - placenta [nTPM]":"16.1","Tissue RNA - pons [nTPM]":"13.0","Tissue RNA - prostate [nTPM]":"8.2","Tissue RNA - rectum [nTPM]":"17.8","Tissue RNA - retina [nTPM]":"19.4","Tissue RNA - salivary gland [nTPM]":"7.7","Tissue RNA - seminal vesicle [nTPM]":"12.5","Tissue RNA - skeletal muscle [nTPM]":"7.0","Tissue RNA - skin 1 [nTPM]":"12.3","Tissue RNA - small intestine [nTPM]":"13.4","Tissue RNA - smooth muscle [nTPM]":"6.7","Tissue RNA - spinal cord [nTPM]":"10.1","Tissue RNA - spleen [nTPM]":"10.0","Tissue RNA - stomach 1 [nTPM]":"14.4","Tissue RNA - testis [nTPM]":"7.4","Tissue RNA - thalamus [nTPM]":"11.3","Tissue RNA - thymus [nTPM]":"3.9","Tissue RNA - thyroid gland [nTPM]":"13.7","Tissue RNA - tongue [nTPM]":"3.3","Tissue RNA - tonsil [nTPM]":"8.7","Tissue RNA - urinary bladder [nTPM]":"11.0","Tissue RNA - vagina [nTPM]":"7.6","Tissue RNA - white matter [nTPM]":"20.2","Cell RNA - A-431 [nTPM]":"45.3","Cell RNA - A549 [nTPM]":"39.2","Cell RNA - AF22 [nTPM]":"44.2","Cell RNA - AN3-CA [nTPM]":"15.5","Cell RNA - ASC diff [nTPM]":"7.5","Cell RNA - ASC TERT1 [nTPM]":"6.0","Cell RNA - BEWO [nTPM]":"61.8","Cell RNA - BJ [nTPM]":"11.2","Cell RNA - BJ hTERT+ [nTPM]":"8.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"26.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"26.7","Cell RNA - CACO-2 [nTPM]":"70.7","Cell RNA - CAPAN-2 [nTPM]":"41.2","Cell RNA - Daudi [nTPM]":"20.2","Cell RNA - EFO-21 [nTPM]":"51.9","Cell RNA - fHDF\/TERT166 [nTPM]":"7.2","Cell RNA - GAMG [nTPM]":"57.8","Cell RNA - HaCaT [nTPM]":"26.3","Cell RNA - HAP1 [nTPM]":"50.1","Cell RNA - HBEC3-KT [nTPM]":"16.2","Cell RNA - HBF TERT88 [nTPM]":"31.0","Cell RNA - HDLM-2 [nTPM]":"8.0","Cell RNA - HEK 293 [nTPM]":"33.0","Cell RNA - HEL [nTPM]":"23.0","Cell RNA - HeLa [nTPM]":"34.4","Cell RNA - Hep G2 [nTPM]":"55.4","Cell RNA - HHSteC [nTPM]":"17.4","Cell RNA - HL-60 [nTPM]":"29.5","Cell RNA - HMC-1 [nTPM]":"17.4","Cell RNA - HSkMC [nTPM]":"15.8","Cell RNA - hTCEpi [nTPM]":"16.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.7","Cell RNA - hTERT-HME1 [nTPM]":"20.4","Cell RNA - hTERT-RPE1 [nTPM]":"10.1","Cell RNA - HUVEC TERT2 [nTPM]":"31.0","Cell RNA - JURKAT [nTPM]":"3.0","Cell RNA - K-562 [nTPM]":"65.9","Cell RNA - Karpas-707 [nTPM]":"7.6","Cell RNA - LHCN-M2 [nTPM]":"13.0","Cell RNA - MCF7 [nTPM]":"49.6","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"27.6","Cell RNA - NTERA-2 [nTPM]":"78.0","Cell RNA - OE19 [nTPM]":"47.8","Cell RNA - PC-3 [nTPM]":"24.0","Cell RNA - REH [nTPM]":"11.6","Cell RNA - RH-30 [nTPM]":"26.3","Cell RNA - RPMI-8226 [nTPM]":"46.8","Cell RNA - RPTEC TERT1 [nTPM]":"63.7","Cell RNA - RT4 [nTPM]":"42.1","Cell RNA - SCLC-21H [nTPM]":"21.1","Cell RNA - SH-SY5Y [nTPM]":"69.0","Cell RNA - SiHa [nTPM]":"38.8","Cell RNA - SK-BR-3 [nTPM]":"81.1","Cell RNA - SK-MEL-30 [nTPM]":"67.3","Cell RNA - SuSa [nTPM]":"72.9","Cell RNA - T-47d [nTPM]":"24.2","Cell RNA - THP-1 [nTPM]":"22.4","Cell RNA - TIME [nTPM]":"18.2","Cell RNA - U-138 MG [nTPM]":"19.6","Cell RNA - U-2 OS [nTPM]":"43.6","Cell RNA - U-2197 [nTPM]":"46.8","Cell RNA - U-251 MG [nTPM]":"34.5","Cell RNA - U-266\/70 [nTPM]":"15.2","Cell RNA - U-266\/84 [nTPM]":"40.8","Cell RNA - U-698 [nTPM]":"12.7","Cell RNA - U-87 MG [nTPM]":"24.1","Cell RNA - U-937 [nTPM]":"28.0","Cell RNA - WM-115 [nTPM]":"32.9","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"3.1","Blood RNA - eosinophil [nTPM]":"2.2","Blood RNA - gdT-cell [nTPM]":"1.4","Blood RNA - intermediate monocyte [nTPM]":"4.5","Blood RNA - MAIT T-cell [nTPM]":"1.5","Blood RNA - memory B-cell [nTPM]":"2.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.3","Blood RNA - myeloid DC [nTPM]":"6.1","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"2.0","Blood RNA - non-classical monocyte [nTPM]":"5.1","Blood RNA - plasmacytoid DC [nTPM]":"3.1","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"7.0","Brain RNA - basal ganglia [nTPM]":"13.7","Brain RNA - cerebellum [nTPM]":"13.7","Brain RNA - cerebral cortex [nTPM]":"10.0","Brain RNA - hippocampal formation [nTPM]":"6.7","Brain RNA - hypothalamus [nTPM]":"9.9","Brain RNA - medulla oblongata [nTPM]":"13.6","Brain RNA - midbrain [nTPM]":"12.2","Brain RNA - pons [nTPM]":"13.0","Brain RNA - spinal cord [nTPM]":"10.1","Brain RNA - thalamus [nTPM]":"11.3","Brain RNA - white matter [nTPM]":"20.2","Single Cell Type RNA - Adipocytes [nTPM]":"31.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.6","Single Cell Type RNA - Astrocytes [nTPM]":"60.7","Single Cell Type RNA - B-cells [nTPM]":"19.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"16.5","Single Cell Type RNA - Bipolar cells [nTPM]":"36.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"9.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"54.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"29.2","Single Cell Type RNA - dendritic cells [nTPM]":"8.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"32.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"27.4","Single Cell Type RNA - Ductal cells [nTPM]":"19.8","Single Cell Type RNA - Early spermatids [nTPM]":"11.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"44.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.2","Single Cell Type RNA - Endothelial cells [nTPM]":"20.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"37.8","Single Cell Type RNA - Erythroid cells [nTPM]":"15.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"26.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.5","Single Cell Type RNA - Fibroblasts [nTPM]":"18.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"44.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"34.2","Single Cell Type RNA - granulocytes [nTPM]":"14.5","Single Cell Type RNA - Granulosa cells [nTPM]":"30.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"153.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.2","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"43.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"22.3","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"23.8","Single Cell Type RNA - Langerhans cells [nTPM]":"10.0","Single Cell Type RNA - Late spermatids [nTPM]":"11.1","Single Cell Type RNA - Leydig cells [nTPM]":"13.1","Single Cell Type RNA - Macrophages [nTPM]":"21.5","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"82.4","Single Cell Type RNA - monocytes [nTPM]":"13.2","Single Cell Type RNA - Muller glia cells [nTPM]":"17.6","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"53.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"439.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.6","Single Cell Type RNA - Paneth cells [nTPM]":"23.7","Single Cell Type RNA - Peritubular cells [nTPM]":"15.8","Single Cell Type RNA - Plasma cells [nTPM]":"12.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"27.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"74.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"47.3","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.9","Single Cell Type RNA - Spermatocytes [nTPM]":"7.0","Single Cell Type RNA - Spermatogonia [nTPM]":"14.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.0","Single Cell Type RNA - T-cells [nTPM]":"7.9","Single Cell Type RNA - Theca cells [nTPM]":"21.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"25.5","Single Cell Type RNA - Urothelial cells [nTPM]":"15.4"},{"Gene":"SLC25A15","Gene synonym":["D13S327","HHH","ORC1","ORNT1"],"Ensembl":"ENSG00000102743","Gene description":"Solute carrier family 25 member 15","Uniprot":["Q9Y619"],"Chromosome":"13","Position":"40789412-40812460","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"37.6","liver":"88.3","pancreas":"52.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"44.5","Hepatocytes":"39.8","Proximal enterocytes":"19.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042146"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042146":"AB_2677874"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.16e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.74e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.46e-4"},"Tissue RNA - adipose tissue [nTPM]":"2.3","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"2.0","Tissue RNA - appendix [nTPM]":"4.1","Tissue RNA - basal ganglia [nTPM]":"2.2","Tissue RNA - bone marrow [nTPM]":"5.6","Tissue RNA - breast [nTPM]":"4.6","Tissue RNA - cerebellum [nTPM]":"2.3","Tissue RNA - cerebral cortex [nTPM]":"2.5","Tissue RNA - cervix [nTPM]":"2.1","Tissue RNA - choroid plexus [nTPM]":"2.3","Tissue RNA - colon [nTPM]":"5.9","Tissue RNA - duodenum [nTPM]":"37.6","Tissue RNA - endometrium 1 [nTPM]":"3.1","Tissue RNA - epididymis [nTPM]":"1.1","Tissue RNA - esophagus [nTPM]":"3.2","Tissue RNA - fallopian tube [nTPM]":"2.6","Tissue RNA - gallbladder [nTPM]":"5.0","Tissue RNA - heart muscle [nTPM]":"2.8","Tissue RNA - hippocampal formation [nTPM]":"1.9","Tissue RNA - hypothalamus [nTPM]":"2.6","Tissue RNA - kidney [nTPM]":"5.6","Tissue RNA - liver [nTPM]":"88.3","Tissue RNA - lung [nTPM]":"2.3","Tissue RNA - lymph node [nTPM]":"4.8","Tissue RNA - medulla oblongata [nTPM]":"2.6","Tissue RNA - midbrain [nTPM]":"2.3","Tissue RNA - ovary [nTPM]":"2.9","Tissue RNA - pancreas [nTPM]":"52.1","Tissue RNA - parathyroid gland [nTPM]":"3.4","Tissue RNA - pituitary gland [nTPM]":"1.3","Tissue RNA - placenta [nTPM]":"2.8","Tissue RNA - pons [nTPM]":"2.5","Tissue RNA - prostate [nTPM]":"2.8","Tissue RNA - rectum [nTPM]":"6.5","Tissue RNA - retina [nTPM]":"2.8","Tissue RNA - salivary gland [nTPM]":"3.4","Tissue RNA - seminal vesicle [nTPM]":"1.8","Tissue RNA - skeletal muscle [nTPM]":"5.9","Tissue RNA - skin 1 [nTPM]":"3.7","Tissue RNA - small intestine [nTPM]":"26.7","Tissue RNA - smooth muscle [nTPM]":"3.4","Tissue RNA - spinal cord [nTPM]":"2.1","Tissue RNA - spleen [nTPM]":"2.5","Tissue RNA - stomach 1 [nTPM]":"5.5","Tissue RNA - testis [nTPM]":"9.4","Tissue RNA - thalamus [nTPM]":"2.4","Tissue RNA - thymus [nTPM]":"5.3","Tissue RNA - thyroid gland [nTPM]":"17.3","Tissue RNA - tongue [nTPM]":"6.0","Tissue RNA - tonsil [nTPM]":"5.3","Tissue RNA - urinary bladder [nTPM]":"2.6","Tissue RNA - vagina [nTPM]":"1.6","Tissue RNA - white matter [nTPM]":"2.9","Cell RNA - A-431 [nTPM]":"7.4","Cell RNA - A549 [nTPM]":"14.7","Cell RNA - AF22 [nTPM]":"16.5","Cell RNA - AN3-CA [nTPM]":"21.3","Cell RNA - ASC diff [nTPM]":"6.5","Cell RNA - ASC TERT1 [nTPM]":"8.2","Cell RNA - BEWO [nTPM]":"17.3","Cell RNA - BJ [nTPM]":"5.6","Cell RNA - BJ hTERT+ [nTPM]":"2.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.9","Cell RNA - CACO-2 [nTPM]":"17.6","Cell RNA - CAPAN-2 [nTPM]":"15.2","Cell RNA - Daudi [nTPM]":"48.0","Cell RNA - EFO-21 [nTPM]":"6.4","Cell RNA - fHDF\/TERT166 [nTPM]":"10.3","Cell RNA - GAMG [nTPM]":"12.7","Cell RNA - HaCaT [nTPM]":"12.6","Cell RNA - HAP1 [nTPM]":"26.6","Cell RNA - HBEC3-KT [nTPM]":"15.5","Cell RNA - HBF TERT88 [nTPM]":"7.0","Cell RNA - HDLM-2 [nTPM]":"11.9","Cell RNA - HEK 293 [nTPM]":"12.4","Cell RNA - HEL [nTPM]":"37.0","Cell RNA - HeLa [nTPM]":"8.6","Cell RNA - Hep G2 [nTPM]":"26.6","Cell RNA - HHSteC [nTPM]":"12.7","Cell RNA - HL-60 [nTPM]":"15.0","Cell RNA - HMC-1 [nTPM]":"5.3","Cell RNA - HSkMC [nTPM]":"9.0","Cell RNA - hTCEpi [nTPM]":"8.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.6","Cell RNA - hTERT-HME1 [nTPM]":"21.9","Cell RNA - hTERT-RPE1 [nTPM]":"4.6","Cell RNA - HUVEC TERT2 [nTPM]":"11.2","Cell RNA - JURKAT [nTPM]":"23.8","Cell RNA - K-562 [nTPM]":"18.1","Cell RNA - Karpas-707 [nTPM]":"7.8","Cell RNA - LHCN-M2 [nTPM]":"11.8","Cell RNA - MCF7 [nTPM]":"28.2","Cell RNA - MOLT-4 [nTPM]":"10.2","Cell RNA - NB-4 [nTPM]":"9.9","Cell RNA - NTERA-2 [nTPM]":"33.2","Cell RNA - OE19 [nTPM]":"32.7","Cell RNA - PC-3 [nTPM]":"7.9","Cell RNA - REH [nTPM]":"25.5","Cell RNA - RH-30 [nTPM]":"12.0","Cell RNA - RPMI-8226 [nTPM]":"10.6","Cell RNA - RPTEC TERT1 [nTPM]":"11.7","Cell RNA - RT4 [nTPM]":"7.0","Cell RNA - SCLC-21H [nTPM]":"7.7","Cell RNA - SH-SY5Y [nTPM]":"20.1","Cell RNA - SiHa [nTPM]":"10.2","Cell RNA - SK-BR-3 [nTPM]":"18.4","Cell RNA - SK-MEL-30 [nTPM]":"10.1","Cell RNA - SuSa [nTPM]":"11.5","Cell RNA - T-47d [nTPM]":"13.6","Cell RNA - THP-1 [nTPM]":"23.2","Cell RNA - TIME [nTPM]":"8.4","Cell RNA - U-138 MG [nTPM]":"8.4","Cell RNA - U-2 OS [nTPM]":"12.1","Cell RNA - U-2197 [nTPM]":"12.7","Cell RNA - U-251 MG [nTPM]":"17.0","Cell RNA - U-266\/70 [nTPM]":"8.9","Cell RNA - U-266\/84 [nTPM]":"9.6","Cell RNA - U-698 [nTPM]":"27.9","Cell RNA - U-87 MG [nTPM]":"8.4","Cell RNA - U-937 [nTPM]":"11.4","Cell RNA - WM-115 [nTPM]":"16.4","Blood RNA - basophil [nTPM]":"1.3","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"1.0","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"1.1","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"2.0","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"1.4","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.9","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"2.0","Brain RNA - basal ganglia [nTPM]":"2.2","Brain RNA - cerebellum [nTPM]":"2.3","Brain RNA - cerebral cortex [nTPM]":"2.5","Brain RNA - hippocampal formation [nTPM]":"1.9","Brain RNA - hypothalamus [nTPM]":"2.6","Brain RNA - medulla oblongata [nTPM]":"2.6","Brain RNA - midbrain [nTPM]":"2.3","Brain RNA - pons [nTPM]":"2.5","Brain RNA - spinal cord [nTPM]":"2.1","Brain RNA - thalamus [nTPM]":"2.4","Brain RNA - white matter [nTPM]":"2.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"3.9","Single Cell Type RNA - B-cells [nTPM]":"1.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"1.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.2","Single Cell Type RNA - dendritic cells [nTPM]":"1.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.1","Single Cell Type RNA - Early spermatids [nTPM]":"4.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"9.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"44.5","Single Cell Type RNA - Fibroblasts [nTPM]":"1.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"39.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.6","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"6.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.7","Single Cell Type RNA - Paneth cells [nTPM]":"2.7","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"6.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"19.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.1","Single Cell Type RNA - Spermatocytes [nTPM]":"5.4","Single Cell Type RNA - Spermatogonia [nTPM]":"9.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - T-cells [nTPM]":"3.2","Single Cell Type RNA - Theca cells [nTPM]":"4.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"SLC25A19","Gene synonym":["DNC","MCPHA","MUP1","TPC"],"Ensembl":"ENSG00000125454","Gene description":"Solute carrier family 25 member 19","Uniprot":["Q9HC21"],"Chromosome":"17","Position":"75272981-75289510","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"82.2","Langerhans cells":"160.3","Spermatocytes":"79.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021936"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA021936":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.05e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.72e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.21e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.9","Tissue RNA - adrenal gland [nTPM]":"31.2","Tissue RNA - amygdala [nTPM]":"11.6","Tissue RNA - appendix [nTPM]":"16.0","Tissue RNA - basal ganglia [nTPM]":"12.4","Tissue RNA - bone marrow [nTPM]":"8.0","Tissue RNA - breast [nTPM]":"6.4","Tissue RNA - cerebellum [nTPM]":"13.1","Tissue RNA - cerebral cortex [nTPM]":"13.3","Tissue RNA - cervix [nTPM]":"7.3","Tissue RNA - choroid plexus [nTPM]":"12.4","Tissue RNA - colon [nTPM]":"9.8","Tissue RNA - duodenum [nTPM]":"9.4","Tissue RNA - endometrium 1 [nTPM]":"6.7","Tissue RNA - epididymis [nTPM]":"2.4","Tissue RNA - esophagus [nTPM]":"8.6","Tissue RNA - fallopian tube [nTPM]":"6.3","Tissue RNA - gallbladder [nTPM]":"6.2","Tissue RNA - heart muscle [nTPM]":"10.6","Tissue RNA - hippocampal formation [nTPM]":"11.7","Tissue RNA - hypothalamus [nTPM]":"12.6","Tissue RNA - kidney [nTPM]":"10.9","Tissue RNA - liver [nTPM]":"8.8","Tissue RNA - lung [nTPM]":"11.7","Tissue RNA - lymph node [nTPM]":"22.9","Tissue RNA - medulla oblongata [nTPM]":"14.9","Tissue RNA - midbrain [nTPM]":"12.6","Tissue RNA - ovary [nTPM]":"6.2","Tissue RNA - pancreas [nTPM]":"8.8","Tissue RNA - parathyroid gland [nTPM]":"8.1","Tissue RNA - pituitary gland [nTPM]":"4.8","Tissue RNA - placenta [nTPM]":"12.1","Tissue RNA - pons [nTPM]":"13.2","Tissue RNA - prostate [nTPM]":"6.1","Tissue RNA - rectum [nTPM]":"8.8","Tissue RNA - retina [nTPM]":"3.1","Tissue RNA - salivary gland [nTPM]":"6.2","Tissue RNA - seminal vesicle [nTPM]":"3.7","Tissue RNA - skeletal muscle [nTPM]":"14.5","Tissue RNA - skin 1 [nTPM]":"4.9","Tissue RNA - small intestine [nTPM]":"8.5","Tissue RNA - smooth muscle [nTPM]":"7.1","Tissue RNA - spinal cord [nTPM]":"13.0","Tissue RNA - spleen [nTPM]":"14.6","Tissue RNA - stomach 1 [nTPM]":"10.9","Tissue RNA - testis [nTPM]":"33.0","Tissue RNA - thalamus [nTPM]":"14.7","Tissue RNA - thymus [nTPM]":"8.6","Tissue RNA - thyroid gland [nTPM]":"6.0","Tissue RNA - tongue [nTPM]":"16.7","Tissue RNA - tonsil [nTPM]":"18.8","Tissue RNA - urinary bladder [nTPM]":"11.5","Tissue RNA - vagina [nTPM]":"5.7","Tissue RNA - white matter [nTPM]":"14.7","Cell RNA - A-431 [nTPM]":"28.3","Cell RNA - A549 [nTPM]":"34.8","Cell RNA - AF22 [nTPM]":"6.2","Cell RNA - AN3-CA [nTPM]":"18.4","Cell RNA - ASC diff [nTPM]":"13.6","Cell RNA - ASC TERT1 [nTPM]":"7.0","Cell RNA - BEWO [nTPM]":"20.0","Cell RNA - BJ [nTPM]":"18.1","Cell RNA - BJ hTERT+ [nTPM]":"7.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.5","Cell RNA - CACO-2 [nTPM]":"59.8","Cell RNA - CAPAN-2 [nTPM]":"17.4","Cell RNA - Daudi [nTPM]":"89.8","Cell RNA - EFO-21 [nTPM]":"12.8","Cell RNA - fHDF\/TERT166 [nTPM]":"6.4","Cell RNA - GAMG [nTPM]":"17.7","Cell RNA - HaCaT [nTPM]":"24.7","Cell RNA - HAP1 [nTPM]":"43.5","Cell RNA - HBEC3-KT [nTPM]":"20.9","Cell RNA - HBF TERT88 [nTPM]":"25.3","Cell RNA - HDLM-2 [nTPM]":"26.5","Cell RNA - HEK 293 [nTPM]":"70.5","Cell RNA - HEL [nTPM]":"41.1","Cell RNA - HeLa [nTPM]":"40.4","Cell RNA - Hep G2 [nTPM]":"58.4","Cell RNA - HHSteC [nTPM]":"11.5","Cell RNA - HL-60 [nTPM]":"58.7","Cell RNA - HMC-1 [nTPM]":"44.9","Cell RNA - HSkMC [nTPM]":"6.1","Cell RNA - hTCEpi [nTPM]":"11.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"31.5","Cell RNA - hTERT-HME1 [nTPM]":"25.2","Cell RNA - hTERT-RPE1 [nTPM]":"4.7","Cell RNA - HUVEC TERT2 [nTPM]":"33.9","Cell RNA - JURKAT [nTPM]":"44.9","Cell RNA - K-562 [nTPM]":"51.0","Cell RNA - Karpas-707 [nTPM]":"41.9","Cell RNA - LHCN-M2 [nTPM]":"6.5","Cell RNA - MCF7 [nTPM]":"59.3","Cell RNA - MOLT-4 [nTPM]":"61.8","Cell RNA - NB-4 [nTPM]":"59.3","Cell RNA - NTERA-2 [nTPM]":"13.5","Cell RNA - OE19 [nTPM]":"55.3","Cell RNA - PC-3 [nTPM]":"67.8","Cell RNA - REH [nTPM]":"47.4","Cell RNA - RH-30 [nTPM]":"19.8","Cell RNA - RPMI-8226 [nTPM]":"85.1","Cell RNA - RPTEC TERT1 [nTPM]":"14.1","Cell RNA - RT4 [nTPM]":"19.7","Cell RNA - SCLC-21H [nTPM]":"60.7","Cell RNA - SH-SY5Y [nTPM]":"15.3","Cell RNA - SiHa [nTPM]":"19.3","Cell RNA - SK-BR-3 [nTPM]":"51.4","Cell RNA - SK-MEL-30 [nTPM]":"22.2","Cell RNA - SuSa [nTPM]":"10.2","Cell RNA - T-47d [nTPM]":"32.1","Cell RNA - THP-1 [nTPM]":"47.3","Cell RNA - TIME [nTPM]":"12.0","Cell RNA - U-138 MG [nTPM]":"12.1","Cell RNA - U-2 OS [nTPM]":"24.1","Cell RNA - U-2197 [nTPM]":"23.5","Cell RNA - U-251 MG [nTPM]":"49.0","Cell RNA - U-266\/70 [nTPM]":"102.7","Cell RNA - U-266\/84 [nTPM]":"53.4","Cell RNA - U-698 [nTPM]":"95.8","Cell RNA - U-87 MG [nTPM]":"9.5","Cell RNA - U-937 [nTPM]":"66.9","Cell RNA - WM-115 [nTPM]":"15.5","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"21.0","Blood RNA - eosinophil [nTPM]":"2.3","Blood RNA - gdT-cell [nTPM]":"16.2","Blood RNA - intermediate monocyte [nTPM]":"25.2","Blood RNA - MAIT T-cell [nTPM]":"16.6","Blood RNA - memory B-cell [nTPM]":"36.3","Blood RNA - memory CD4 T-cell [nTPM]":"12.7","Blood RNA - memory CD8 T-cell [nTPM]":"15.4","Blood RNA - myeloid DC [nTPM]":"24.9","Blood RNA - naive B-cell [nTPM]":"29.7","Blood RNA - naive CD4 T-cell [nTPM]":"14.2","Blood RNA - naive CD8 T-cell [nTPM]":"14.7","Blood RNA - neutrophil [nTPM]":"1.7","Blood RNA - NK-cell [nTPM]":"10.0","Blood RNA - non-classical monocyte [nTPM]":"14.8","Blood RNA - plasmacytoid DC [nTPM]":"31.0","Blood RNA - T-reg [nTPM]":"17.7","Blood RNA - total PBMC [nTPM]":"14.5","Brain RNA - amygdala [nTPM]":"11.6","Brain RNA - basal ganglia [nTPM]":"12.4","Brain RNA - cerebellum [nTPM]":"13.1","Brain RNA - cerebral cortex [nTPM]":"13.3","Brain RNA - hippocampal formation [nTPM]":"11.7","Brain RNA - hypothalamus [nTPM]":"12.6","Brain RNA - medulla oblongata [nTPM]":"14.9","Brain RNA - midbrain [nTPM]":"12.6","Brain RNA - pons [nTPM]":"13.2","Brain RNA - spinal cord [nTPM]":"13.0","Brain RNA - thalamus [nTPM]":"14.7","Brain RNA - white matter [nTPM]":"14.7","Single Cell Type RNA - Adipocytes [nTPM]":"5.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.7","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"27.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"1.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"6.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.5","Single Cell Type RNA - dendritic cells [nTPM]":"13.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"6.5","Single Cell Type RNA - Early spermatids [nTPM]":"18.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.7","Single Cell Type RNA - Endothelial cells [nTPM]":"6.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"11.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"82.2","Single Cell Type RNA - Fibroblasts [nTPM]":"8.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.5","Single Cell Type RNA - granulocytes [nTPM]":"11.4","Single Cell Type RNA - Granulosa cells [nTPM]":"2.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"2.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"44.1","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.2","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"9.5","Single Cell Type RNA - Langerhans cells [nTPM]":"160.3","Single Cell Type RNA - Late spermatids [nTPM]":"24.1","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"31.5","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"38.8","Single Cell Type RNA - Muller glia cells [nTPM]":"1.6","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.1","Single Cell Type RNA - Paneth cells [nTPM]":"8.6","Single Cell Type RNA - Peritubular cells [nTPM]":"3.4","Single Cell Type RNA - Plasma cells [nTPM]":"26.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.0","Single Cell Type RNA - Spermatocytes [nTPM]":"79.6","Single Cell Type RNA - Spermatogonia [nTPM]":"11.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.9","Single Cell Type RNA - T-cells [nTPM]":"12.5","Single Cell Type RNA - Theca cells [nTPM]":"11.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.0","Single Cell Type RNA - Urothelial cells [nTPM]":"9.7"},{"Gene":"SLC25A20","Gene synonym":["CAC","CACT"],"Ensembl":"ENSG00000178537","Gene description":"Solute carrier family 25 member 20","Uniprot":["O43772"],"Chromosome":"3","Position":"48856926-48898904","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"148.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"42.2","Hepatocytes":"64.2","Proximal enterocytes":"51.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"96.1","RPMI-8226":"138.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016862","HPA029863"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Mitochondria","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA016862":"AB_1857028","HPA029863":"AB_10602893"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Tissue RNA - adipose tissue [nTPM]":"20.7","Tissue RNA - adrenal gland [nTPM]":"29.9","Tissue RNA - amygdala [nTPM]":"16.3","Tissue RNA - appendix [nTPM]":"11.9","Tissue RNA - basal ganglia [nTPM]":"18.2","Tissue RNA - bone marrow [nTPM]":"10.7","Tissue RNA - breast [nTPM]":"17.9","Tissue RNA - cerebellum [nTPM]":"18.6","Tissue RNA - cerebral cortex [nTPM]":"16.4","Tissue RNA - cervix [nTPM]":"8.3","Tissue RNA - choroid plexus [nTPM]":"15.3","Tissue RNA - colon [nTPM]":"26.5","Tissue RNA - duodenum [nTPM]":"65.6","Tissue RNA - endometrium 1 [nTPM]":"10.4","Tissue RNA - epididymis [nTPM]":"4.6","Tissue RNA - esophagus [nTPM]":"9.1","Tissue RNA - fallopian tube [nTPM]":"12.8","Tissue RNA - gallbladder [nTPM]":"15.7","Tissue RNA - heart muscle [nTPM]":"62.8","Tissue RNA - hippocampal formation [nTPM]":"15.5","Tissue RNA - hypothalamus [nTPM]":"17.9","Tissue RNA - kidney [nTPM]":"25.6","Tissue RNA - liver [nTPM]":"148.3","Tissue RNA - lung [nTPM]":"15.6","Tissue RNA - lymph node [nTPM]":"14.6","Tissue RNA - medulla oblongata [nTPM]":"17.7","Tissue RNA - midbrain [nTPM]":"17.4","Tissue RNA - ovary [nTPM]":"5.9","Tissue RNA - pancreas [nTPM]":"30.4","Tissue RNA - parathyroid gland [nTPM]":"17.3","Tissue RNA - pituitary gland [nTPM]":"11.6","Tissue RNA - placenta [nTPM]":"7.3","Tissue RNA - pons [nTPM]":"17.8","Tissue RNA - prostate [nTPM]":"11.7","Tissue RNA - rectum [nTPM]":"23.5","Tissue RNA - retina [nTPM]":"4.5","Tissue RNA - salivary gland [nTPM]":"19.9","Tissue RNA - seminal vesicle [nTPM]":"9.0","Tissue RNA - skeletal muscle [nTPM]":"66.5","Tissue RNA - skin 1 [nTPM]":"10.4","Tissue RNA - small intestine [nTPM]":"52.7","Tissue RNA - smooth muscle [nTPM]":"15.1","Tissue RNA - spinal cord [nTPM]":"17.4","Tissue RNA - spleen [nTPM]":"20.6","Tissue RNA - stomach 1 [nTPM]":"21.0","Tissue RNA - testis [nTPM]":"9.1","Tissue RNA - thalamus [nTPM]":"17.5","Tissue RNA - thymus [nTPM]":"17.3","Tissue RNA - thyroid gland [nTPM]":"11.4","Tissue RNA - tongue [nTPM]":"61.1","Tissue RNA - tonsil [nTPM]":"16.1","Tissue RNA - urinary bladder [nTPM]":"11.3","Tissue RNA - vagina [nTPM]":"8.4","Tissue RNA - white matter [nTPM]":"18.4","Cell RNA - A-431 [nTPM]":"4.1","Cell RNA - A549 [nTPM]":"12.8","Cell RNA - AF22 [nTPM]":"9.7","Cell RNA - AN3-CA [nTPM]":"13.8","Cell RNA - ASC diff [nTPM]":"30.1","Cell RNA - ASC TERT1 [nTPM]":"11.8","Cell RNA - BEWO [nTPM]":"1.9","Cell RNA - BJ [nTPM]":"22.3","Cell RNA - BJ hTERT+ [nTPM]":"11.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.8","Cell RNA - CACO-2 [nTPM]":"16.3","Cell RNA - CAPAN-2 [nTPM]":"19.1","Cell RNA - Daudi [nTPM]":"19.0","Cell RNA - EFO-21 [nTPM]":"15.6","Cell RNA - fHDF\/TERT166 [nTPM]":"35.1","Cell RNA - GAMG [nTPM]":"18.7","Cell RNA - HaCaT [nTPM]":"4.1","Cell RNA - HAP1 [nTPM]":"24.5","Cell RNA - HBEC3-KT [nTPM]":"9.8","Cell RNA - HBF TERT88 [nTPM]":"11.6","Cell RNA - HDLM-2 [nTPM]":"47.9","Cell RNA - HEK 293 [nTPM]":"11.8","Cell RNA - HEL [nTPM]":"26.4","Cell RNA - HeLa [nTPM]":"19.2","Cell RNA - Hep G2 [nTPM]":"20.4","Cell RNA - HHSteC [nTPM]":"14.0","Cell RNA - HL-60 [nTPM]":"27.8","Cell RNA - HMC-1 [nTPM]":"48.1","Cell RNA - HSkMC [nTPM]":"14.9","Cell RNA - hTCEpi [nTPM]":"11.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.6","Cell RNA - hTERT-HME1 [nTPM]":"3.8","Cell RNA - hTERT-RPE1 [nTPM]":"6.1","Cell RNA - HUVEC TERT2 [nTPM]":"20.2","Cell RNA - JURKAT [nTPM]":"28.1","Cell RNA - K-562 [nTPM]":"24.1","Cell RNA - Karpas-707 [nTPM]":"96.1","Cell RNA - LHCN-M2 [nTPM]":"20.2","Cell RNA - MCF7 [nTPM]":"10.9","Cell RNA - MOLT-4 [nTPM]":"30.4","Cell RNA - NB-4 [nTPM]":"13.7","Cell RNA - NTERA-2 [nTPM]":"5.1","Cell RNA - OE19 [nTPM]":"22.9","Cell RNA - PC-3 [nTPM]":"27.6","Cell RNA - REH [nTPM]":"10.6","Cell RNA - RH-30 [nTPM]":"5.9","Cell RNA - RPMI-8226 [nTPM]":"138.4","Cell RNA - RPTEC TERT1 [nTPM]":"16.4","Cell RNA - RT4 [nTPM]":"10.1","Cell RNA - SCLC-21H [nTPM]":"3.9","Cell RNA - SH-SY5Y [nTPM]":"13.6","Cell RNA - SiHa [nTPM]":"20.7","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"11.4","Cell RNA - SuSa [nTPM]":"13.6","Cell RNA - T-47d [nTPM]":"30.5","Cell RNA - THP-1 [nTPM]":"12.9","Cell RNA - TIME [nTPM]":"16.6","Cell RNA - U-138 MG [nTPM]":"17.2","Cell RNA - U-2 OS [nTPM]":"3.2","Cell RNA - U-2197 [nTPM]":"25.5","Cell RNA - U-251 MG [nTPM]":"16.4","Cell RNA - U-266\/70 [nTPM]":"35.6","Cell RNA - U-266\/84 [nTPM]":"27.0","Cell RNA - U-698 [nTPM]":"21.8","Cell RNA - U-87 MG [nTPM]":"24.5","Cell RNA - U-937 [nTPM]":"19.5","Cell RNA - WM-115 [nTPM]":"23.3","Blood RNA - basophil [nTPM]":"60.8","Blood RNA - classical monocyte [nTPM]":"101.1","Blood RNA - eosinophil [nTPM]":"215.2","Blood RNA - gdT-cell [nTPM]":"97.4","Blood RNA - intermediate monocyte [nTPM]":"79.7","Blood RNA - MAIT T-cell [nTPM]":"62.2","Blood RNA - memory B-cell [nTPM]":"36.8","Blood RNA - memory CD4 T-cell [nTPM]":"53.1","Blood RNA - memory CD8 T-cell [nTPM]":"71.2","Blood RNA - myeloid DC [nTPM]":"97.5","Blood RNA - naive B-cell [nTPM]":"33.0","Blood RNA - naive CD4 T-cell [nTPM]":"41.2","Blood RNA - naive CD8 T-cell [nTPM]":"69.1","Blood RNA - neutrophil [nTPM]":"48.6","Blood RNA - NK-cell [nTPM]":"64.6","Blood RNA - non-classical monocyte [nTPM]":"83.7","Blood RNA - plasmacytoid DC [nTPM]":"120.5","Blood RNA - T-reg [nTPM]":"60.7","Blood RNA - total PBMC [nTPM]":"112.3","Brain RNA - amygdala [nTPM]":"16.3","Brain RNA - basal ganglia [nTPM]":"18.2","Brain RNA - cerebellum [nTPM]":"18.6","Brain RNA - cerebral cortex [nTPM]":"16.4","Brain RNA - hippocampal formation [nTPM]":"15.5","Brain RNA - hypothalamus [nTPM]":"17.9","Brain RNA - medulla oblongata [nTPM]":"17.7","Brain RNA - midbrain [nTPM]":"17.4","Brain RNA - pons [nTPM]":"17.8","Brain RNA - spinal cord [nTPM]":"17.4","Brain RNA - thalamus [nTPM]":"17.5","Brain RNA - white matter [nTPM]":"18.4","Single Cell Type RNA - Adipocytes [nTPM]":"7.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.7","Single Cell Type RNA - Astrocytes [nTPM]":"13.1","Single Cell Type RNA - B-cells [nTPM]":"7.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"1.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"42.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"4.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.3","Single Cell Type RNA - dendritic cells [nTPM]":"13.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"28.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.5","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.6","Single Cell Type RNA - Endothelial cells [nTPM]":"5.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.3","Single Cell Type RNA - Erythroid cells [nTPM]":"16.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.3","Single Cell Type RNA - Fibroblasts [nTPM]":"6.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"3.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"64.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.7","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"13.4","Single Cell Type RNA - Langerhans cells [nTPM]":"4.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.8","Single Cell Type RNA - Leydig cells [nTPM]":"10.5","Single Cell Type RNA - Macrophages [nTPM]":"10.0","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"31.3","Single Cell Type RNA - Muller glia cells [nTPM]":"2.9","Single Cell Type RNA - NK-cells [nTPM]":"32.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.7","Single Cell Type RNA - Paneth cells [nTPM]":"16.4","Single Cell Type RNA - Peritubular cells [nTPM]":"12.4","Single Cell Type RNA - Plasma cells [nTPM]":"12.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"51.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.3","Single Cell Type RNA - Spermatocytes [nTPM]":"8.3","Single Cell Type RNA - Spermatogonia [nTPM]":"7.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - T-cells [nTPM]":"14.4","Single Cell Type RNA - Theca cells [nTPM]":"27.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.6","Single Cell Type RNA - Urothelial cells [nTPM]":"2.9"},{"Gene":"SLC25A21","Gene synonym":["ODC","ODC1"],"Ensembl":"ENSG00000183032","Gene description":"Solute carrier family 25 member 21","Uniprot":["Q9BQT8"],"Chromosome":"14","Position":"36677921-37172606","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"6.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"27.8","Excitatory neurons":"14.1","Exocrine glandular cells":"10.0","Inhibitory neurons":"10.4","Oligodendrocyte precursor cells":"11.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"K-562":"26.4","Karpas-707":"54.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000662"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA000662":"AB_1080000"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.09e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.9","Tissue RNA - adrenal gland [nTPM]":"1.2","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"6.3","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"0.6","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.6","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"1.3","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"1.2","Tissue RNA - fallopian tube [nTPM]":"0.7","Tissue RNA - gallbladder [nTPM]":"0.6","Tissue RNA - heart muscle [nTPM]":"1.3","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.4","Tissue RNA - kidney [nTPM]":"1.6","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"0.5","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"2.0","Tissue RNA - pancreas [nTPM]":"2.8","Tissue RNA - parathyroid gland [nTPM]":"0.9","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"1.6","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"1.0","Tissue RNA - salivary gland [nTPM]":"1.6","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"1.2","Tissue RNA - smooth muscle [nTPM]":"0.7","Tissue RNA - spinal cord [nTPM]":"0.4","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"0.8","Tissue RNA - testis [nTPM]":"3.9","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"1.5","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.6","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"1.3","Cell RNA - A549 [nTPM]":"1.0","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"3.2","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"1.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.7","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.9","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"1.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"1.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.7","Cell RNA - HBF TERT88 [nTPM]":"0.6","Cell RNA - HDLM-2 [nTPM]":"0.8","Cell RNA - HEK 293 [nTPM]":"9.5","Cell RNA - HEL [nTPM]":"0.9","Cell RNA - HeLa [nTPM]":"0.8","Cell RNA - Hep G2 [nTPM]":"0.8","Cell RNA - HHSteC [nTPM]":"1.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.7","Cell RNA - hTCEpi [nTPM]":"1.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.5","Cell RNA - hTERT-RPE1 [nTPM]":"0.9","Cell RNA - HUVEC TERT2 [nTPM]":"3.9","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"26.4","Cell RNA - Karpas-707 [nTPM]":"54.4","Cell RNA - LHCN-M2 [nTPM]":"0.8","Cell RNA - MCF7 [nTPM]":"2.7","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"2.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"4.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.8","Cell RNA - RT4 [nTPM]":"3.9","Cell RNA - SCLC-21H [nTPM]":"2.6","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"2.6","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"1.3","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"2.9","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"1.9","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.6","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"2.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.4","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.4","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.3","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.9","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"27.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.5","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.1","Single Cell Type RNA - Spermatocytes [nTPM]":"3.1","Single Cell Type RNA - Spermatogonia [nTPM]":"3.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"1.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"SLC25A22","Gene synonym":["EIEE3","FLJ13044","GC1","NET44"],"Ensembl":"ENSG00000177542","Gene description":"Solute carrier family 25 member 22","Uniprot":["Q9H936"],"Chromosome":"11","Position":"790475-798281","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"83.1","pancreas":"83.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"143.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014662"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA014662":"AB_10600808"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Tissue RNA - adipose tissue [nTPM]":"15.8","Tissue RNA - adrenal gland [nTPM]":"13.6","Tissue RNA - amygdala [nTPM]":"49.1","Tissue RNA - appendix [nTPM]":"11.0","Tissue RNA - basal ganglia [nTPM]":"59.8","Tissue RNA - bone marrow [nTPM]":"7.5","Tissue RNA - breast [nTPM]":"11.2","Tissue RNA - cerebellum [nTPM]":"17.9","Tissue RNA - cerebral cortex [nTPM]":"83.1","Tissue RNA - cervix [nTPM]":"9.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"10.0","Tissue RNA - duodenum [nTPM]":"12.9","Tissue RNA - endometrium 1 [nTPM]":"9.6","Tissue RNA - epididymis [nTPM]":"2.1","Tissue RNA - esophagus [nTPM]":"15.2","Tissue RNA - fallopian tube [nTPM]":"10.4","Tissue RNA - gallbladder [nTPM]":"4.1","Tissue RNA - heart muscle [nTPM]":"7.7","Tissue RNA - hippocampal formation [nTPM]":"74.2","Tissue RNA - hypothalamus [nTPM]":"7.9","Tissue RNA - kidney [nTPM]":"15.1","Tissue RNA - liver [nTPM]":"40.2","Tissue RNA - lung [nTPM]":"15.1","Tissue RNA - lymph node [nTPM]":"10.1","Tissue RNA - medulla oblongata [nTPM]":"24.5","Tissue RNA - midbrain [nTPM]":"11.1","Tissue RNA - ovary [nTPM]":"12.7","Tissue RNA - pancreas [nTPM]":"83.4","Tissue RNA - parathyroid gland [nTPM]":"4.0","Tissue RNA - pituitary gland [nTPM]":"48.7","Tissue RNA - placenta [nTPM]":"5.0","Tissue RNA - pons [nTPM]":"25.4","Tissue RNA - prostate [nTPM]":"13.9","Tissue RNA - rectum [nTPM]":"3.0","Tissue RNA - retina [nTPM]":"16.1","Tissue RNA - salivary gland [nTPM]":"14.4","Tissue RNA - seminal vesicle [nTPM]":"4.3","Tissue RNA - skeletal muscle [nTPM]":"2.0","Tissue RNA - skin 1 [nTPM]":"14.2","Tissue RNA - small intestine [nTPM]":"12.2","Tissue RNA - smooth muscle [nTPM]":"3.7","Tissue RNA - spinal cord [nTPM]":"2.4","Tissue RNA - spleen [nTPM]":"13.9","Tissue RNA - stomach 1 [nTPM]":"13.5","Tissue RNA - testis [nTPM]":"19.1","Tissue RNA - thalamus [nTPM]":"19.1","Tissue RNA - thymus [nTPM]":"6.3","Tissue RNA - thyroid gland [nTPM]":"9.4","Tissue RNA - tongue [nTPM]":"0.5","Tissue RNA - tonsil [nTPM]":"6.2","Tissue RNA - urinary bladder [nTPM]":"10.3","Tissue RNA - vagina [nTPM]":"10.3","Tissue RNA - white matter [nTPM]":"40.2","Cell RNA - A-431 [nTPM]":"56.2","Cell RNA - A549 [nTPM]":"35.7","Cell RNA - AF22 [nTPM]":"20.4","Cell RNA - AN3-CA [nTPM]":"18.6","Cell RNA - ASC diff [nTPM]":"8.3","Cell RNA - ASC TERT1 [nTPM]":"14.8","Cell RNA - BEWO [nTPM]":"19.4","Cell RNA - BJ [nTPM]":"26.3","Cell RNA - BJ hTERT+ [nTPM]":"21.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"28.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.7","Cell RNA - CACO-2 [nTPM]":"34.9","Cell RNA - CAPAN-2 [nTPM]":"37.1","Cell RNA - Daudi [nTPM]":"16.8","Cell RNA - EFO-21 [nTPM]":"19.2","Cell RNA - fHDF\/TERT166 [nTPM]":"21.6","Cell RNA - GAMG [nTPM]":"31.9","Cell RNA - HaCaT [nTPM]":"48.8","Cell RNA - HAP1 [nTPM]":"22.4","Cell RNA - HBEC3-KT [nTPM]":"31.1","Cell RNA - HBF TERT88 [nTPM]":"6.3","Cell RNA - HDLM-2 [nTPM]":"31.9","Cell RNA - HEK 293 [nTPM]":"41.4","Cell RNA - HEL [nTPM]":"15.4","Cell RNA - HeLa [nTPM]":"18.2","Cell RNA - Hep G2 [nTPM]":"21.9","Cell RNA - HHSteC [nTPM]":"35.8","Cell RNA - HL-60 [nTPM]":"24.7","Cell RNA - HMC-1 [nTPM]":"25.0","Cell RNA - HSkMC [nTPM]":"14.9","Cell RNA - hTCEpi [nTPM]":"18.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.4","Cell RNA - hTERT-HME1 [nTPM]":"22.6","Cell RNA - hTERT-RPE1 [nTPM]":"8.8","Cell RNA - HUVEC TERT2 [nTPM]":"13.0","Cell RNA - JURKAT [nTPM]":"19.3","Cell RNA - K-562 [nTPM]":"31.8","Cell RNA - Karpas-707 [nTPM]":"25.3","Cell RNA - LHCN-M2 [nTPM]":"12.7","Cell RNA - MCF7 [nTPM]":"33.9","Cell RNA - MOLT-4 [nTPM]":"26.3","Cell RNA - NB-4 [nTPM]":"23.5","Cell RNA - NTERA-2 [nTPM]":"44.8","Cell RNA - OE19 [nTPM]":"33.9","Cell RNA - PC-3 [nTPM]":"53.7","Cell RNA - REH [nTPM]":"30.9","Cell RNA - RH-30 [nTPM]":"11.2","Cell RNA - RPMI-8226 [nTPM]":"38.9","Cell RNA - RPTEC TERT1 [nTPM]":"16.8","Cell RNA - RT4 [nTPM]":"9.2","Cell RNA - SCLC-21H [nTPM]":"100.3","Cell RNA - SH-SY5Y [nTPM]":"45.3","Cell RNA - SiHa [nTPM]":"15.0","Cell RNA - SK-BR-3 [nTPM]":"35.9","Cell RNA - SK-MEL-30 [nTPM]":"18.7","Cell RNA - SuSa [nTPM]":"3.1","Cell RNA - T-47d [nTPM]":"17.4","Cell RNA - THP-1 [nTPM]":"12.5","Cell RNA - TIME [nTPM]":"13.0","Cell RNA - U-138 MG [nTPM]":"32.1","Cell RNA - U-2 OS [nTPM]":"21.5","Cell RNA - U-2197 [nTPM]":"14.8","Cell RNA - U-251 MG [nTPM]":"25.0","Cell RNA - U-266\/70 [nTPM]":"22.1","Cell RNA - U-266\/84 [nTPM]":"14.3","Cell RNA - U-698 [nTPM]":"21.5","Cell RNA - U-87 MG [nTPM]":"37.8","Cell RNA - U-937 [nTPM]":"22.2","Cell RNA - WM-115 [nTPM]":"19.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.6","Blood RNA - eosinophil [nTPM]":"2.5","Blood RNA - gdT-cell [nTPM]":"3.7","Blood RNA - intermediate monocyte [nTPM]":"3.3","Blood RNA - MAIT T-cell [nTPM]":"2.2","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"2.3","Blood RNA - memory CD8 T-cell [nTPM]":"3.9","Blood RNA - myeloid DC [nTPM]":"1.8","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"2.3","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"2.0","Blood RNA - non-classical monocyte [nTPM]":"3.4","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"1.3","Blood RNA - total PBMC [nTPM]":"1.6","Brain RNA - amygdala [nTPM]":"49.1","Brain RNA - basal ganglia [nTPM]":"59.8","Brain RNA - cerebellum [nTPM]":"17.9","Brain RNA - cerebral cortex [nTPM]":"83.1","Brain RNA - hippocampal formation [nTPM]":"74.2","Brain RNA - hypothalamus [nTPM]":"7.9","Brain RNA - medulla oblongata [nTPM]":"24.5","Brain RNA - midbrain [nTPM]":"11.1","Brain RNA - pons [nTPM]":"25.4","Brain RNA - spinal cord [nTPM]":"2.4","Brain RNA - thalamus [nTPM]":"19.1","Brain RNA - white matter [nTPM]":"40.2","Single Cell Type RNA - Adipocytes [nTPM]":"5.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.6","Single Cell Type RNA - Astrocytes [nTPM]":"7.8","Single Cell Type RNA - B-cells [nTPM]":"8.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"143.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"5.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.1","Single Cell Type RNA - dendritic cells [nTPM]":"8.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"22.0","Single Cell Type RNA - Early spermatids [nTPM]":"12.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.0","Single Cell Type RNA - Endothelial cells [nTPM]":"7.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"2.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.3","Single Cell Type RNA - Fibroblasts [nTPM]":"5.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.2","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"7.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"17.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.3","Single Cell Type RNA - Horizontal cells [nTPM]":"43.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.6","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.8","Single Cell Type RNA - Langerhans cells [nTPM]":"4.6","Single Cell Type RNA - Late spermatids [nTPM]":"7.7","Single Cell Type RNA - Leydig cells [nTPM]":"4.7","Single Cell Type RNA - Macrophages [nTPM]":"4.1","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"6.6","Single Cell Type RNA - Muller glia cells [nTPM]":"16.0","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.1","Single Cell Type RNA - Paneth cells [nTPM]":"7.8","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"13.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"32.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.7","Single Cell Type RNA - Spermatocytes [nTPM]":"1.8","Single Cell Type RNA - Spermatogonia [nTPM]":"10.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.1","Single Cell Type RNA - T-cells [nTPM]":"8.2","Single Cell Type RNA - Theca cells [nTPM]":"13.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.9","Single Cell Type RNA - Urothelial cells [nTPM]":"8.8"},{"Gene":"SLC25A24","Gene synonym":["APC1","DKFZp586G0123"],"Ensembl":"ENSG00000085491","Gene description":"Solute carrier family 25 member 24","Uniprot":["Q6NUK1"],"Chromosome":"1","Position":"108134043-108200849","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"126.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028519","HPA063636"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"19000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA028519":"AB_10603890","HPA063636":"AB_2685068"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.01e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.54e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.0","Tissue RNA - adrenal gland [nTPM]":"6.2","Tissue RNA - amygdala [nTPM]":"0.8","Tissue RNA - appendix [nTPM]":"5.3","Tissue RNA - basal ganglia [nTPM]":"0.7","Tissue RNA - bone marrow [nTPM]":"3.8","Tissue RNA - breast [nTPM]":"8.2","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"1.3","Tissue RNA - cervix [nTPM]":"12.5","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"13.5","Tissue RNA - duodenum [nTPM]":"11.4","Tissue RNA - endometrium 1 [nTPM]":"6.6","Tissue RNA - epididymis [nTPM]":"3.2","Tissue RNA - esophagus [nTPM]":"6.0","Tissue RNA - fallopian tube [nTPM]":"6.7","Tissue RNA - gallbladder [nTPM]":"6.8","Tissue RNA - heart muscle [nTPM]":"4.9","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"0.8","Tissue RNA - kidney [nTPM]":"6.3","Tissue RNA - liver [nTPM]":"1.6","Tissue RNA - lung [nTPM]":"9.1","Tissue RNA - lymph node [nTPM]":"5.1","Tissue RNA - medulla oblongata [nTPM]":"0.8","Tissue RNA - midbrain [nTPM]":"0.7","Tissue RNA - ovary [nTPM]":"5.9","Tissue RNA - pancreas [nTPM]":"4.2","Tissue RNA - parathyroid gland [nTPM]":"8.2","Tissue RNA - pituitary gland [nTPM]":"2.8","Tissue RNA - placenta [nTPM]":"9.4","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"4.0","Tissue RNA - rectum [nTPM]":"16.0","Tissue RNA - retina [nTPM]":"6.7","Tissue RNA - salivary gland [nTPM]":"6.7","Tissue RNA - seminal vesicle [nTPM]":"4.6","Tissue RNA - skeletal muscle [nTPM]":"3.7","Tissue RNA - skin 1 [nTPM]":"4.3","Tissue RNA - small intestine [nTPM]":"12.3","Tissue RNA - smooth muscle [nTPM]":"8.7","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"5.7","Tissue RNA - stomach 1 [nTPM]":"6.9","Tissue RNA - testis [nTPM]":"3.2","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"5.0","Tissue RNA - thyroid gland [nTPM]":"7.1","Tissue RNA - tongue [nTPM]":"4.5","Tissue RNA - tonsil [nTPM]":"4.9","Tissue RNA - urinary bladder [nTPM]":"10.1","Tissue RNA - vagina [nTPM]":"7.0","Tissue RNA - white matter [nTPM]":"0.7","Cell RNA - A-431 [nTPM]":"38.2","Cell RNA - A549 [nTPM]":"8.9","Cell RNA - AF22 [nTPM]":"28.8","Cell RNA - AN3-CA [nTPM]":"8.6","Cell RNA - ASC diff [nTPM]":"17.9","Cell RNA - ASC TERT1 [nTPM]":"23.4","Cell RNA - BEWO [nTPM]":"11.4","Cell RNA - BJ [nTPM]":"13.0","Cell RNA - BJ hTERT+ [nTPM]":"17.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"25.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"27.4","Cell RNA - CACO-2 [nTPM]":"11.3","Cell RNA - CAPAN-2 [nTPM]":"12.9","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"10.3","Cell RNA - fHDF\/TERT166 [nTPM]":"28.7","Cell RNA - GAMG [nTPM]":"10.9","Cell RNA - HaCaT [nTPM]":"14.1","Cell RNA - HAP1 [nTPM]":"7.9","Cell RNA - HBEC3-KT [nTPM]":"24.0","Cell RNA - HBF TERT88 [nTPM]":"35.1","Cell RNA - HDLM-2 [nTPM]":"7.9","Cell RNA - HEK 293 [nTPM]":"4.4","Cell RNA - HEL [nTPM]":"2.4","Cell RNA - HeLa [nTPM]":"13.4","Cell RNA - Hep G2 [nTPM]":"5.2","Cell RNA - HHSteC [nTPM]":"14.9","Cell RNA - HL-60 [nTPM]":"6.1","Cell RNA - HMC-1 [nTPM]":"4.9","Cell RNA - HSkMC [nTPM]":"17.6","Cell RNA - hTCEpi [nTPM]":"17.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.0","Cell RNA - hTERT-HME1 [nTPM]":"18.5","Cell RNA - hTERT-RPE1 [nTPM]":"16.8","Cell RNA - HUVEC TERT2 [nTPM]":"19.6","Cell RNA - JURKAT [nTPM]":"5.7","Cell RNA - K-562 [nTPM]":"6.2","Cell RNA - Karpas-707 [nTPM]":"13.0","Cell RNA - LHCN-M2 [nTPM]":"32.2","Cell RNA - MCF7 [nTPM]":"28.7","Cell RNA - MOLT-4 [nTPM]":"3.7","Cell RNA - NB-4 [nTPM]":"1.4","Cell RNA - NTERA-2 [nTPM]":"14.3","Cell RNA - OE19 [nTPM]":"17.3","Cell RNA - PC-3 [nTPM]":"8.1","Cell RNA - REH [nTPM]":"5.7","Cell RNA - RH-30 [nTPM]":"33.9","Cell RNA - RPMI-8226 [nTPM]":"12.6","Cell RNA - RPTEC TERT1 [nTPM]":"16.9","Cell RNA - RT4 [nTPM]":"22.8","Cell RNA - SCLC-21H [nTPM]":"5.0","Cell RNA - SH-SY5Y [nTPM]":"8.7","Cell RNA - SiHa [nTPM]":"17.4","Cell RNA - SK-BR-3 [nTPM]":"14.9","Cell RNA - SK-MEL-30 [nTPM]":"17.5","Cell RNA - SuSa [nTPM]":"27.5","Cell RNA - T-47d [nTPM]":"13.3","Cell RNA - THP-1 [nTPM]":"10.7","Cell RNA - TIME [nTPM]":"10.5","Cell RNA - U-138 MG [nTPM]":"13.8","Cell RNA - U-2 OS [nTPM]":"6.2","Cell RNA - U-2197 [nTPM]":"23.2","Cell RNA - U-251 MG [nTPM]":"15.0","Cell RNA - U-266\/70 [nTPM]":"3.0","Cell RNA - U-266\/84 [nTPM]":"2.3","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"5.0","Cell RNA - U-937 [nTPM]":"11.8","Cell RNA - WM-115 [nTPM]":"8.2","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.7","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.8","Brain RNA - basal ganglia [nTPM]":"0.7","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"1.3","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"0.8","Brain RNA - medulla oblongata [nTPM]":"0.8","Brain RNA - midbrain [nTPM]":"0.7","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"0.7","Single Cell Type RNA - Adipocytes [nTPM]":"33.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"54.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.8","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"24.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"20.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Bipolar cells [nTPM]":"14.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"33.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.1","Single Cell Type RNA - dendritic cells [nTPM]":"16.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"126.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"31.2","Single Cell Type RNA - Early spermatids [nTPM]":"3.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"62.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"46.7","Single Cell Type RNA - Endothelial cells [nTPM]":"28.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.1","Single Cell Type RNA - Erythroid cells [nTPM]":"6.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"36.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"60.2","Single Cell Type RNA - Fibroblasts [nTPM]":"23.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"40.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"61.7","Single Cell Type RNA - granulocytes [nTPM]":"22.2","Single Cell Type RNA - Granulosa cells [nTPM]":"20.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"29.6","Single Cell Type RNA - Hepatocytes [nTPM]":"1.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"54.1","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"43.2","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"51.8","Single Cell Type RNA - Langerhans cells [nTPM]":"32.8","Single Cell Type RNA - Late spermatids [nTPM]":"2.9","Single Cell Type RNA - Leydig cells [nTPM]":"19.6","Single Cell Type RNA - Macrophages [nTPM]":"50.0","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"44.7","Single Cell Type RNA - Muller glia cells [nTPM]":"12.7","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"67.6","Single Cell Type RNA - Paneth cells [nTPM]":"51.2","Single Cell Type RNA - Peritubular cells [nTPM]":"18.0","Single Cell Type RNA - Plasma cells [nTPM]":"9.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"54.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"24.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"55.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"33.9","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.5","Single Cell Type RNA - Spermatocytes [nTPM]":"6.2","Single Cell Type RNA - Spermatogonia [nTPM]":"2.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"24.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.2","Single Cell Type RNA - T-cells [nTPM]":"23.9","Single Cell Type RNA - Theca cells [nTPM]":"41.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"59.1","Single Cell Type RNA - Urothelial cells [nTPM]":"33.8"},{"Gene":"SLC25A26","Gene synonym":[],"Ensembl":"ENSG00000144741","Gene description":"Solute carrier family 25 member 26","Uniprot":["Q70HW3"],"Chromosome":"3","Position":"66133610-66388116","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026887"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA026887":"AB_2189921"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.73e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Tissue RNA - adipose tissue [nTPM]":"15.8","Tissue RNA - adrenal gland [nTPM]":"16.0","Tissue RNA - amygdala [nTPM]":"9.6","Tissue RNA - appendix [nTPM]":"5.6","Tissue RNA - basal ganglia [nTPM]":"9.9","Tissue RNA - bone marrow [nTPM]":"12.9","Tissue RNA - breast [nTPM]":"15.0","Tissue RNA - cerebellum [nTPM]":"8.7","Tissue RNA - cerebral cortex [nTPM]":"11.0","Tissue RNA - cervix [nTPM]":"12.7","Tissue RNA - choroid plexus [nTPM]":"6.8","Tissue RNA - colon [nTPM]":"18.1","Tissue RNA - duodenum [nTPM]":"7.8","Tissue RNA - endometrium 1 [nTPM]":"13.3","Tissue RNA - epididymis [nTPM]":"9.4","Tissue RNA - esophagus [nTPM]":"15.9","Tissue RNA - fallopian tube [nTPM]":"12.7","Tissue RNA - gallbladder [nTPM]":"7.8","Tissue RNA - heart muscle [nTPM]":"28.3","Tissue RNA - hippocampal formation [nTPM]":"10.1","Tissue RNA - hypothalamus [nTPM]":"8.7","Tissue RNA - kidney [nTPM]":"18.5","Tissue RNA - liver [nTPM]":"25.9","Tissue RNA - lung [nTPM]":"11.6","Tissue RNA - lymph node [nTPM]":"10.7","Tissue RNA - medulla oblongata [nTPM]":"9.1","Tissue RNA - midbrain [nTPM]":"9.3","Tissue RNA - ovary [nTPM]":"16.5","Tissue RNA - pancreas [nTPM]":"15.5","Tissue RNA - parathyroid gland [nTPM]":"14.9","Tissue RNA - pituitary gland [nTPM]":"10.2","Tissue RNA - placenta [nTPM]":"7.7","Tissue RNA - pons [nTPM]":"9.2","Tissue RNA - prostate [nTPM]":"13.5","Tissue RNA - rectum [nTPM]":"9.5","Tissue RNA - retina [nTPM]":"8.5","Tissue RNA - salivary gland [nTPM]":"16.1","Tissue RNA - seminal vesicle [nTPM]":"9.0","Tissue RNA - skeletal muscle [nTPM]":"42.4","Tissue RNA - skin 1 [nTPM]":"22.0","Tissue RNA - small intestine [nTPM]":"13.3","Tissue RNA - smooth muscle [nTPM]":"7.8","Tissue RNA - spinal cord [nTPM]":"9.3","Tissue RNA - spleen [nTPM]":"13.5","Tissue RNA - stomach 1 [nTPM]":"17.4","Tissue RNA - testis [nTPM]":"14.3","Tissue RNA - thalamus [nTPM]":"11.1","Tissue RNA - thymus [nTPM]":"8.6","Tissue RNA - thyroid gland [nTPM]":"15.8","Tissue RNA - tongue [nTPM]":"21.0","Tissue RNA - tonsil [nTPM]":"9.6","Tissue RNA - urinary bladder [nTPM]":"17.5","Tissue RNA - vagina [nTPM]":"14.1","Tissue RNA - white matter [nTPM]":"11.3","Cell RNA - A-431 [nTPM]":"10.7","Cell RNA - A549 [nTPM]":"10.4","Cell RNA - AF22 [nTPM]":"6.5","Cell RNA - AN3-CA [nTPM]":"12.4","Cell RNA - ASC diff [nTPM]":"13.9","Cell RNA - ASC TERT1 [nTPM]":"13.1","Cell RNA - BEWO [nTPM]":"13.9","Cell RNA - BJ [nTPM]":"9.0","Cell RNA - BJ hTERT+ [nTPM]":"15.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.2","Cell RNA - CACO-2 [nTPM]":"13.5","Cell RNA - CAPAN-2 [nTPM]":"13.9","Cell RNA - Daudi [nTPM]":"12.3","Cell RNA - EFO-21 [nTPM]":"5.5","Cell RNA - fHDF\/TERT166 [nTPM]":"15.1","Cell RNA - GAMG [nTPM]":"14.3","Cell RNA - HaCaT [nTPM]":"7.6","Cell RNA - HAP1 [nTPM]":"7.3","Cell RNA - HBEC3-KT [nTPM]":"15.8","Cell RNA - HBF TERT88 [nTPM]":"11.7","Cell RNA - HDLM-2 [nTPM]":"11.5","Cell RNA - HEK 293 [nTPM]":"16.8","Cell RNA - HEL [nTPM]":"16.3","Cell RNA - HeLa [nTPM]":"8.1","Cell RNA - Hep G2 [nTPM]":"19.2","Cell RNA - HHSteC [nTPM]":"14.7","Cell RNA - HL-60 [nTPM]":"22.5","Cell RNA - HMC-1 [nTPM]":"13.4","Cell RNA - HSkMC [nTPM]":"17.7","Cell RNA - hTCEpi [nTPM]":"29.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.4","Cell RNA - hTERT-HME1 [nTPM]":"21.3","Cell RNA - hTERT-RPE1 [nTPM]":"11.2","Cell RNA - HUVEC TERT2 [nTPM]":"8.9","Cell RNA - JURKAT [nTPM]":"21.5","Cell RNA - K-562 [nTPM]":"9.2","Cell RNA - Karpas-707 [nTPM]":"12.8","Cell RNA - LHCN-M2 [nTPM]":"12.9","Cell RNA - MCF7 [nTPM]":"12.5","Cell RNA - MOLT-4 [nTPM]":"9.9","Cell RNA - NB-4 [nTPM]":"28.3","Cell RNA - NTERA-2 [nTPM]":"20.8","Cell RNA - OE19 [nTPM]":"23.2","Cell RNA - PC-3 [nTPM]":"6.8","Cell RNA - REH [nTPM]":"10.0","Cell RNA - RH-30 [nTPM]":"11.7","Cell RNA - RPMI-8226 [nTPM]":"19.4","Cell RNA - RPTEC TERT1 [nTPM]":"10.1","Cell RNA - RT4 [nTPM]":"8.3","Cell RNA - SCLC-21H [nTPM]":"5.4","Cell RNA - SH-SY5Y [nTPM]":"14.6","Cell RNA - SiHa [nTPM]":"12.4","Cell RNA - SK-BR-3 [nTPM]":"11.8","Cell RNA - SK-MEL-30 [nTPM]":"21.4","Cell RNA - SuSa [nTPM]":"10.9","Cell RNA - T-47d [nTPM]":"9.8","Cell RNA - THP-1 [nTPM]":"19.7","Cell RNA - TIME [nTPM]":"10.4","Cell RNA - U-138 MG [nTPM]":"12.7","Cell RNA - U-2 OS [nTPM]":"11.0","Cell RNA - U-2197 [nTPM]":"15.9","Cell RNA - U-251 MG [nTPM]":"16.6","Cell RNA - U-266\/70 [nTPM]":"21.1","Cell RNA - U-266\/84 [nTPM]":"30.6","Cell RNA - U-698 [nTPM]":"15.1","Cell RNA - U-87 MG [nTPM]":"17.4","Cell RNA - U-937 [nTPM]":"21.1","Cell RNA - WM-115 [nTPM]":"14.7","Blood RNA - basophil [nTPM]":"1.8","Blood RNA - classical monocyte [nTPM]":"9.9","Blood RNA - eosinophil [nTPM]":"6.1","Blood RNA - gdT-cell [nTPM]":"15.4","Blood RNA - intermediate monocyte [nTPM]":"10.8","Blood RNA - MAIT T-cell [nTPM]":"14.5","Blood RNA - memory B-cell [nTPM]":"19.3","Blood RNA - memory CD4 T-cell [nTPM]":"16.9","Blood RNA - memory CD8 T-cell [nTPM]":"16.4","Blood RNA - myeloid DC [nTPM]":"18.3","Blood RNA - naive B-cell [nTPM]":"16.2","Blood RNA - naive CD4 T-cell [nTPM]":"20.5","Blood RNA - naive CD8 T-cell [nTPM]":"17.5","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"18.1","Blood RNA - non-classical monocyte [nTPM]":"6.7","Blood RNA - plasmacytoid DC [nTPM]":"17.5","Blood RNA - T-reg [nTPM]":"17.7","Blood RNA - total PBMC [nTPM]":"13.4","Brain RNA - amygdala [nTPM]":"9.6","Brain RNA - basal ganglia [nTPM]":"9.9","Brain RNA - cerebellum [nTPM]":"8.7","Brain RNA - cerebral cortex [nTPM]":"11.0","Brain RNA - hippocampal formation [nTPM]":"10.1","Brain RNA - hypothalamus [nTPM]":"8.7","Brain RNA - medulla oblongata [nTPM]":"9.1","Brain RNA - midbrain [nTPM]":"9.3","Brain RNA - pons [nTPM]":"9.2","Brain RNA - spinal cord [nTPM]":"9.3","Brain RNA - thalamus [nTPM]":"11.1","Brain RNA - white matter [nTPM]":"11.3","Single Cell Type RNA - Adipocytes [nTPM]":"11.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"22.2","Single Cell Type RNA - Astrocytes [nTPM]":"22.9","Single Cell Type RNA - B-cells [nTPM]":"29.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"35.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"38.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"45.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"28.5","Single Cell Type RNA - Bipolar cells [nTPM]":"17.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"36.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"34.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"106.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"25.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"36.8","Single Cell Type RNA - dendritic cells [nTPM]":"27.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"28.8","Single Cell Type RNA - Early spermatids [nTPM]":"33.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.6","Single Cell Type RNA - Endothelial cells [nTPM]":"20.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.6","Single Cell Type RNA - Erythroid cells [nTPM]":"9.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"55.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"45.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"44.6","Single Cell Type RNA - Fibroblasts [nTPM]":"26.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.1","Single Cell Type RNA - granulocytes [nTPM]":"19.6","Single Cell Type RNA - Granulosa cells [nTPM]":"21.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.2","Single Cell Type RNA - Hepatocytes [nTPM]":"39.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.3","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"51.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"29.2","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"22.3","Single Cell Type RNA - Langerhans cells [nTPM]":"26.5","Single Cell Type RNA - Late spermatids [nTPM]":"28.6","Single Cell Type RNA - Leydig cells [nTPM]":"16.1","Single Cell Type RNA - Macrophages [nTPM]":"15.8","Single Cell Type RNA - Melanocytes [nTPM]":"37.4","Single Cell Type RNA - Microglial cells [nTPM]":"31.9","Single Cell Type RNA - monocytes [nTPM]":"21.4","Single Cell Type RNA - Muller glia cells [nTPM]":"26.5","Single Cell Type RNA - NK-cells [nTPM]":"32.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"32.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"63.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"27.6","Single Cell Type RNA - Paneth cells [nTPM]":"20.8","Single Cell Type RNA - Peritubular cells [nTPM]":"21.8","Single Cell Type RNA - Plasma cells [nTPM]":"18.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"49.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"30.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"57.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.5","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"31.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.1","Single Cell Type RNA - Spermatocytes [nTPM]":"29.4","Single Cell Type RNA - Spermatogonia [nTPM]":"32.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"36.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"32.7","Single Cell Type RNA - T-cells [nTPM]":"39.6","Single Cell Type RNA - Theca cells [nTPM]":"22.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"33.3","Single Cell Type RNA - Urothelial cells [nTPM]":"37.8"},{"Gene":"SLC25A3","Gene synonym":["PHC"],"Ensembl":"ENSG00000075415","Gene description":"Solute carrier family 25 member 3","Uniprot":["Q00325"],"Chromosome":"12","Position":"98593591-98606379","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"1537.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"1748.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045709"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"83000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA045709":"AB_10965843"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.11e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.66e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"},"Tissue RNA - adipose tissue [nTPM]":"300.9","Tissue RNA - adrenal gland [nTPM]":"550.7","Tissue RNA - amygdala [nTPM]":"131.2","Tissue RNA - appendix [nTPM]":"184.7","Tissue RNA - basal ganglia [nTPM]":"136.0","Tissue RNA - bone marrow [nTPM]":"209.2","Tissue RNA - breast [nTPM]":"267.5","Tissue RNA - cerebellum [nTPM]":"159.3","Tissue RNA - cerebral cortex [nTPM]":"146.5","Tissue RNA - cervix [nTPM]":"224.3","Tissue RNA - choroid plexus [nTPM]":"209.3","Tissue RNA - colon [nTPM]":"418.9","Tissue RNA - duodenum [nTPM]":"396.4","Tissue RNA - endometrium 1 [nTPM]":"283.5","Tissue RNA - epididymis [nTPM]":"226.1","Tissue RNA - esophagus [nTPM]":"437.7","Tissue RNA - fallopian tube [nTPM]":"248.9","Tissue RNA - gallbladder [nTPM]":"136.2","Tissue RNA - heart muscle [nTPM]":"1237.8","Tissue RNA - hippocampal formation [nTPM]":"132.6","Tissue RNA - hypothalamus [nTPM]":"160.4","Tissue RNA - kidney [nTPM]":"419.8","Tissue RNA - liver [nTPM]":"370.1","Tissue RNA - lung [nTPM]":"255.7","Tissue RNA - lymph node [nTPM]":"201.7","Tissue RNA - medulla oblongata [nTPM]":"148.9","Tissue RNA - midbrain [nTPM]":"149.6","Tissue RNA - ovary [nTPM]":"290.2","Tissue RNA - pancreas [nTPM]":"392.2","Tissue RNA - parathyroid gland [nTPM]":"499.7","Tissue RNA - pituitary gland [nTPM]":"216.9","Tissue RNA - placenta [nTPM]":"192.4","Tissue RNA - pons [nTPM]":"153.0","Tissue RNA - prostate [nTPM]":"209.9","Tissue RNA - rectum [nTPM]":"347.6","Tissue RNA - retina [nTPM]":"167.2","Tissue RNA - salivary gland [nTPM]":"302.7","Tissue RNA - seminal vesicle [nTPM]":"220.9","Tissue RNA - skeletal muscle [nTPM]":"1537.4","Tissue RNA - skin 1 [nTPM]":"275.7","Tissue RNA - small intestine [nTPM]":"321.2","Tissue RNA - smooth muscle [nTPM]":"257.4","Tissue RNA - spinal cord [nTPM]":"150.4","Tissue RNA - spleen [nTPM]":"235.1","Tissue RNA - stomach 1 [nTPM]":"423.5","Tissue RNA - testis [nTPM]":"90.8","Tissue RNA - thalamus [nTPM]":"159.0","Tissue RNA - thymus [nTPM]":"205.7","Tissue RNA - thyroid gland [nTPM]":"225.1","Tissue RNA - tongue [nTPM]":"1233.2","Tissue RNA - tonsil [nTPM]":"312.8","Tissue RNA - urinary bladder [nTPM]":"294.7","Tissue RNA - vagina [nTPM]":"264.6","Tissue RNA - white matter [nTPM]":"135.4","Cell RNA - A-431 [nTPM]":"731.4","Cell RNA - A549 [nTPM]":"447.1","Cell RNA - AF22 [nTPM]":"620.0","Cell RNA - AN3-CA [nTPM]":"509.6","Cell RNA - ASC diff [nTPM]":"534.1","Cell RNA - ASC TERT1 [nTPM]":"891.5","Cell RNA - BEWO [nTPM]":"1005.3","Cell RNA - BJ [nTPM]":"622.8","Cell RNA - BJ hTERT+ [nTPM]":"724.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"704.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"573.4","Cell RNA - CACO-2 [nTPM]":"787.6","Cell RNA - CAPAN-2 [nTPM]":"316.4","Cell RNA - Daudi [nTPM]":"1003.2","Cell RNA - EFO-21 [nTPM]":"376.9","Cell RNA - fHDF\/TERT166 [nTPM]":"633.0","Cell RNA - GAMG [nTPM]":"320.3","Cell RNA - HaCaT [nTPM]":"573.7","Cell RNA - HAP1 [nTPM]":"616.9","Cell RNA - HBEC3-KT [nTPM]":"741.3","Cell RNA - HBF TERT88 [nTPM]":"680.6","Cell RNA - HDLM-2 [nTPM]":"402.9","Cell RNA - HEK 293 [nTPM]":"651.8","Cell RNA - HEL [nTPM]":"589.5","Cell RNA - HeLa [nTPM]":"297.4","Cell RNA - Hep G2 [nTPM]":"563.3","Cell RNA - HHSteC [nTPM]":"683.0","Cell RNA - HL-60 [nTPM]":"665.7","Cell RNA - HMC-1 [nTPM]":"416.6","Cell RNA - HSkMC [nTPM]":"857.3","Cell RNA - hTCEpi [nTPM]":"616.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"494.2","Cell RNA - hTERT-HME1 [nTPM]":"681.2","Cell RNA - hTERT-RPE1 [nTPM]":"994.3","Cell RNA - HUVEC TERT2 [nTPM]":"990.8","Cell RNA - JURKAT [nTPM]":"488.8","Cell RNA - K-562 [nTPM]":"654.9","Cell RNA - Karpas-707 [nTPM]":"240.5","Cell RNA - LHCN-M2 [nTPM]":"782.7","Cell RNA - MCF7 [nTPM]":"436.5","Cell RNA - MOLT-4 [nTPM]":"642.5","Cell RNA - NB-4 [nTPM]":"724.2","Cell RNA - NTERA-2 [nTPM]":"605.4","Cell RNA - OE19 [nTPM]":"540.6","Cell RNA - PC-3 [nTPM]":"988.5","Cell RNA - REH [nTPM]":"703.0","Cell RNA - RH-30 [nTPM]":"730.3","Cell RNA - RPMI-8226 [nTPM]":"1075.0","Cell RNA - RPTEC TERT1 [nTPM]":"858.8","Cell RNA - RT4 [nTPM]":"559.6","Cell RNA - SCLC-21H [nTPM]":"355.5","Cell RNA - SH-SY5Y [nTPM]":"506.1","Cell RNA - SiHa [nTPM]":"740.1","Cell RNA - SK-BR-3 [nTPM]":"565.5","Cell RNA - SK-MEL-30 [nTPM]":"1009.8","Cell RNA - SuSa [nTPM]":"504.4","Cell RNA - T-47d [nTPM]":"771.0","Cell RNA - THP-1 [nTPM]":"676.3","Cell RNA - TIME [nTPM]":"782.0","Cell RNA - U-138 MG [nTPM]":"371.2","Cell RNA - U-2 OS [nTPM]":"390.0","Cell RNA - U-2197 [nTPM]":"442.8","Cell RNA - U-251 MG [nTPM]":"603.4","Cell RNA - U-266\/70 [nTPM]":"486.5","Cell RNA - U-266\/84 [nTPM]":"648.5","Cell RNA - U-698 [nTPM]":"678.1","Cell RNA - U-87 MG [nTPM]":"295.6","Cell RNA - U-937 [nTPM]":"368.3","Cell RNA - WM-115 [nTPM]":"494.9","Blood RNA - basophil [nTPM]":"184.7","Blood RNA - classical monocyte [nTPM]":"408.9","Blood RNA - eosinophil [nTPM]":"223.2","Blood RNA - gdT-cell [nTPM]":"244.7","Blood RNA - intermediate monocyte [nTPM]":"520.2","Blood RNA - MAIT T-cell [nTPM]":"285.6","Blood RNA - memory B-cell [nTPM]":"298.5","Blood RNA - memory CD4 T-cell [nTPM]":"270.8","Blood RNA - memory CD8 T-cell [nTPM]":"271.4","Blood RNA - myeloid DC [nTPM]":"534.7","Blood RNA - naive B-cell [nTPM]":"222.6","Blood RNA - naive CD4 T-cell [nTPM]":"281.3","Blood RNA - naive CD8 T-cell [nTPM]":"269.8","Blood RNA - neutrophil [nTPM]":"166.6","Blood RNA - NK-cell [nTPM]":"288.5","Blood RNA - non-classical monocyte [nTPM]":"545.2","Blood RNA - plasmacytoid DC [nTPM]":"321.7","Blood RNA - T-reg [nTPM]":"377.4","Blood RNA - total PBMC [nTPM]":"637.0","Brain RNA - amygdala [nTPM]":"131.2","Brain RNA - basal ganglia [nTPM]":"136.0","Brain RNA - cerebellum [nTPM]":"159.3","Brain RNA - cerebral cortex [nTPM]":"146.5","Brain RNA - hippocampal formation [nTPM]":"132.6","Brain RNA - hypothalamus [nTPM]":"160.4","Brain RNA - medulla oblongata [nTPM]":"148.9","Brain RNA - midbrain [nTPM]":"149.6","Brain RNA - pons [nTPM]":"153.0","Brain RNA - spinal cord [nTPM]":"150.4","Brain RNA - thalamus [nTPM]":"159.0","Brain RNA - white matter [nTPM]":"135.4","Single Cell Type RNA - Adipocytes [nTPM]":"319.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"214.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"294.8","Single Cell Type RNA - Astrocytes [nTPM]":"46.0","Single Cell Type RNA - B-cells [nTPM]":"392.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"376.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"590.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"751.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"495.1","Single Cell Type RNA - Bipolar cells [nTPM]":"223.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"442.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"549.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1748.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"370.3","Single Cell Type RNA - Club cells [nTPM]":"384.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"215.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"79.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"785.9","Single Cell Type RNA - dendritic cells [nTPM]":"480.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"727.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"874.6","Single Cell Type RNA - Ductal cells [nTPM]":"512.1","Single Cell Type RNA - Early spermatids [nTPM]":"41.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"217.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"275.3","Single Cell Type RNA - Endothelial cells [nTPM]":"328.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"312.4","Single Cell Type RNA - Erythroid cells [nTPM]":"413.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"44.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"879.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"946.2","Single Cell Type RNA - Fibroblasts [nTPM]":"393.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"390.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"288.7","Single Cell Type RNA - granulocytes [nTPM]":"210.4","Single Cell Type RNA - Granulosa cells [nTPM]":"477.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"278.1","Single Cell Type RNA - Hepatocytes [nTPM]":"416.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"589.4","Single Cell Type RNA - Horizontal cells [nTPM]":"292.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"49.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"470.7","Single Cell Type RNA - Ionocytes [nTPM]":"370.2","Single Cell Type RNA - Kupffer cells [nTPM]":"467.9","Single Cell Type RNA - Langerhans cells [nTPM]":"280.7","Single Cell Type RNA - Late spermatids [nTPM]":"29.0","Single Cell Type RNA - Leydig cells [nTPM]":"255.1","Single Cell Type RNA - Macrophages [nTPM]":"449.1","Single Cell Type RNA - Melanocytes [nTPM]":"437.6","Single Cell Type RNA - Microglial cells [nTPM]":"34.7","Single Cell Type RNA - monocytes [nTPM]":"593.5","Single Cell Type RNA - Muller glia cells [nTPM]":"317.3","Single Cell Type RNA - NK-cells [nTPM]":"294.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"32.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"42.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"632.9","Single Cell Type RNA - Paneth cells [nTPM]":"602.7","Single Cell Type RNA - Peritubular cells [nTPM]":"256.5","Single Cell Type RNA - Plasma cells [nTPM]":"442.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"652.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"945.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1029.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"201.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"230.2","Single Cell Type RNA - Sertoli cells [nTPM]":"302.4","Single Cell Type RNA - Skeletal myocytes [nTPM]":"470.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"733.5","Single Cell Type RNA - Spermatocytes [nTPM]":"126.1","Single Cell Type RNA - Spermatogonia [nTPM]":"169.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"796.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"362.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"814.7","Single Cell Type RNA - T-cells [nTPM]":"356.3","Single Cell Type RNA - Theca cells [nTPM]":"536.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"729.1","Single Cell Type RNA - Urothelial cells [nTPM]":"769.9"},{"Gene":"SLC25A32","Gene synonym":["MFTC"],"Ensembl":"ENSG00000164933","Gene description":"Solute carrier family 25 member 32","Uniprot":["Q9H2D1"],"Chromosome":"8","Position":"103398635-103415189","Protein class":["Disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024763","HPA047402"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA024763":null,"HPA047402":"AB_2680032"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.23e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.09e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.53e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Tissue RNA - adipose tissue [nTPM]":"13.5","Tissue RNA - adrenal gland [nTPM]":"7.2","Tissue RNA - amygdala [nTPM]":"3.1","Tissue RNA - appendix [nTPM]":"12.5","Tissue RNA - basal ganglia [nTPM]":"3.9","Tissue RNA - bone marrow [nTPM]":"14.6","Tissue RNA - breast [nTPM]":"11.2","Tissue RNA - cerebellum [nTPM]":"4.1","Tissue RNA - cerebral cortex [nTPM]":"4.8","Tissue RNA - cervix [nTPM]":"8.6","Tissue RNA - choroid plexus [nTPM]":"2.9","Tissue RNA - colon [nTPM]":"7.7","Tissue RNA - duodenum [nTPM]":"6.8","Tissue RNA - endometrium 1 [nTPM]":"10.7","Tissue RNA - epididymis [nTPM]":"7.5","Tissue RNA - esophagus [nTPM]":"7.3","Tissue RNA - fallopian tube [nTPM]":"9.3","Tissue RNA - gallbladder [nTPM]":"11.5","Tissue RNA - heart muscle [nTPM]":"9.7","Tissue RNA - hippocampal formation [nTPM]":"4.1","Tissue RNA - hypothalamus [nTPM]":"4.5","Tissue RNA - kidney [nTPM]":"9.6","Tissue RNA - liver [nTPM]":"17.9","Tissue RNA - lung [nTPM]":"8.5","Tissue RNA - lymph node [nTPM]":"16.9","Tissue RNA - medulla oblongata [nTPM]":"4.7","Tissue RNA - midbrain [nTPM]":"4.6","Tissue RNA - ovary [nTPM]":"9.6","Tissue RNA - pancreas [nTPM]":"8.5","Tissue RNA - parathyroid gland [nTPM]":"8.8","Tissue RNA - pituitary gland [nTPM]":"11.3","Tissue RNA - placenta [nTPM]":"10.1","Tissue RNA - pons [nTPM]":"4.6","Tissue RNA - prostate [nTPM]":"8.0","Tissue RNA - rectum [nTPM]":"7.7","Tissue RNA - retina [nTPM]":"1.4","Tissue RNA - salivary gland [nTPM]":"6.4","Tissue RNA - seminal vesicle [nTPM]":"7.5","Tissue RNA - skeletal muscle [nTPM]":"9.6","Tissue RNA - skin 1 [nTPM]":"6.9","Tissue RNA - small intestine [nTPM]":"7.6","Tissue RNA - smooth muscle [nTPM]":"10.9","Tissue RNA - spinal cord [nTPM]":"4.6","Tissue RNA - spleen [nTPM]":"12.7","Tissue RNA - stomach 1 [nTPM]":"7.0","Tissue RNA - testis [nTPM]":"6.4","Tissue RNA - thalamus [nTPM]":"4.0","Tissue RNA - thymus [nTPM]":"8.7","Tissue RNA - thyroid gland [nTPM]":"7.1","Tissue RNA - tongue [nTPM]":"9.2","Tissue RNA - tonsil [nTPM]":"12.8","Tissue RNA - urinary bladder [nTPM]":"15.0","Tissue RNA - vagina [nTPM]":"7.0","Tissue RNA - white matter [nTPM]":"5.3","Cell RNA - A-431 [nTPM]":"33.7","Cell RNA - A549 [nTPM]":"11.5","Cell RNA - AF22 [nTPM]":"10.5","Cell RNA - AN3-CA [nTPM]":"18.3","Cell RNA - ASC diff [nTPM]":"21.3","Cell RNA - ASC TERT1 [nTPM]":"23.3","Cell RNA - BEWO [nTPM]":"10.3","Cell RNA - BJ [nTPM]":"27.4","Cell RNA - BJ hTERT+ [nTPM]":"39.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"30.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"31.4","Cell RNA - CACO-2 [nTPM]":"14.0","Cell RNA - CAPAN-2 [nTPM]":"19.6","Cell RNA - Daudi [nTPM]":"73.8","Cell RNA - EFO-21 [nTPM]":"25.8","Cell RNA - fHDF\/TERT166 [nTPM]":"29.5","Cell RNA - GAMG [nTPM]":"17.7","Cell RNA - HaCaT [nTPM]":"20.4","Cell RNA - HAP1 [nTPM]":"22.5","Cell RNA - HBEC3-KT [nTPM]":"22.5","Cell RNA - HBF TERT88 [nTPM]":"47.0","Cell RNA - HDLM-2 [nTPM]":"45.5","Cell RNA - HEK 293 [nTPM]":"16.1","Cell RNA - HEL [nTPM]":"53.5","Cell RNA - HeLa [nTPM]":"8.5","Cell RNA - Hep G2 [nTPM]":"18.3","Cell RNA - HHSteC [nTPM]":"37.4","Cell RNA - HL-60 [nTPM]":"26.5","Cell RNA - HMC-1 [nTPM]":"23.1","Cell RNA - HSkMC [nTPM]":"23.1","Cell RNA - hTCEpi [nTPM]":"17.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"34.5","Cell RNA - hTERT-HME1 [nTPM]":"51.2","Cell RNA - hTERT-RPE1 [nTPM]":"8.6","Cell RNA - HUVEC TERT2 [nTPM]":"32.5","Cell RNA - JURKAT [nTPM]":"19.4","Cell RNA - K-562 [nTPM]":"33.9","Cell RNA - Karpas-707 [nTPM]":"25.9","Cell RNA - LHCN-M2 [nTPM]":"30.5","Cell RNA - MCF7 [nTPM]":"13.5","Cell RNA - MOLT-4 [nTPM]":"45.0","Cell RNA - NB-4 [nTPM]":"21.6","Cell RNA - NTERA-2 [nTPM]":"17.1","Cell RNA - OE19 [nTPM]":"39.3","Cell RNA - PC-3 [nTPM]":"23.6","Cell RNA - REH [nTPM]":"33.6","Cell RNA - RH-30 [nTPM]":"16.3","Cell RNA - RPMI-8226 [nTPM]":"50.8","Cell RNA - RPTEC TERT1 [nTPM]":"20.8","Cell RNA - RT4 [nTPM]":"12.7","Cell RNA - SCLC-21H [nTPM]":"28.0","Cell RNA - SH-SY5Y [nTPM]":"17.2","Cell RNA - SiHa [nTPM]":"13.6","Cell RNA - SK-BR-3 [nTPM]":"22.3","Cell RNA - SK-MEL-30 [nTPM]":"48.9","Cell RNA - SuSa [nTPM]":"10.5","Cell RNA - T-47d [nTPM]":"19.3","Cell RNA - THP-1 [nTPM]":"18.5","Cell RNA - TIME [nTPM]":"22.6","Cell RNA - U-138 MG [nTPM]":"36.7","Cell RNA - U-2 OS [nTPM]":"24.9","Cell RNA - U-2197 [nTPM]":"44.2","Cell RNA - U-251 MG [nTPM]":"36.2","Cell RNA - U-266\/70 [nTPM]":"19.2","Cell RNA - U-266\/84 [nTPM]":"19.7","Cell RNA - U-698 [nTPM]":"76.8","Cell RNA - U-87 MG [nTPM]":"31.0","Cell RNA - U-937 [nTPM]":"38.1","Cell RNA - WM-115 [nTPM]":"27.5","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"3.3","Blood RNA - eosinophil [nTPM]":"1.6","Blood RNA - gdT-cell [nTPM]":"6.0","Blood RNA - intermediate monocyte [nTPM]":"3.7","Blood RNA - MAIT T-cell [nTPM]":"7.3","Blood RNA - memory B-cell [nTPM]":"7.0","Blood RNA - memory CD4 T-cell [nTPM]":"6.4","Blood RNA - memory CD8 T-cell [nTPM]":"6.9","Blood RNA - myeloid DC [nTPM]":"4.1","Blood RNA - naive B-cell [nTPM]":"4.8","Blood RNA - naive CD4 T-cell [nTPM]":"6.5","Blood RNA - naive CD8 T-cell [nTPM]":"6.7","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"5.2","Blood RNA - non-classical monocyte [nTPM]":"4.3","Blood RNA - plasmacytoid DC [nTPM]":"3.5","Blood RNA - T-reg [nTPM]":"5.5","Blood RNA - total PBMC [nTPM]":"5.7","Brain RNA - amygdala [nTPM]":"3.1","Brain RNA - basal ganglia [nTPM]":"3.9","Brain RNA - cerebellum [nTPM]":"4.1","Brain RNA - cerebral cortex [nTPM]":"4.8","Brain RNA - hippocampal formation [nTPM]":"4.1","Brain RNA - hypothalamus [nTPM]":"4.5","Brain RNA - medulla oblongata [nTPM]":"4.7","Brain RNA - midbrain [nTPM]":"4.6","Brain RNA - pons [nTPM]":"4.6","Brain RNA - spinal cord [nTPM]":"4.6","Brain RNA - thalamus [nTPM]":"4.0","Brain RNA - white matter [nTPM]":"5.3","Single Cell Type RNA - Adipocytes [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.3","Single Cell Type RNA - Astrocytes [nTPM]":"10.1","Single Cell Type RNA - B-cells [nTPM]":"46.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"23.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"32.5","Single Cell Type RNA - Bipolar cells [nTPM]":"9.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"5.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.9","Single Cell Type RNA - dendritic cells [nTPM]":"20.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.8","Single Cell Type RNA - Early spermatids [nTPM]":"4.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.0","Single Cell Type RNA - Endothelial cells [nTPM]":"22.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.4","Single Cell Type RNA - Erythroid cells [nTPM]":"16.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"30.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.6","Single Cell Type RNA - Fibroblasts [nTPM]":"19.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"27.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.1","Single Cell Type RNA - granulocytes [nTPM]":"8.9","Single Cell Type RNA - Granulosa cells [nTPM]":"8.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.0","Single Cell Type RNA - Hepatocytes [nTPM]":"15.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.2","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.1","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"7.3","Single Cell Type RNA - Langerhans cells [nTPM]":"11.6","Single Cell Type RNA - Late spermatids [nTPM]":"4.7","Single Cell Type RNA - Leydig cells [nTPM]":"9.3","Single Cell Type RNA - Macrophages [nTPM]":"16.2","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"24.4","Single Cell Type RNA - monocytes [nTPM]":"9.9","Single Cell Type RNA - Muller glia cells [nTPM]":"7.6","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"25.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"46.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.0","Single Cell Type RNA - Paneth cells [nTPM]":"3.1","Single Cell Type RNA - Peritubular cells [nTPM]":"8.6","Single Cell Type RNA - Plasma cells [nTPM]":"56.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.1","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.7","Single Cell Type RNA - Spermatocytes [nTPM]":"22.9","Single Cell Type RNA - Spermatogonia [nTPM]":"17.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"32.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"25.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.0","Single Cell Type RNA - T-cells [nTPM]":"27.7","Single Cell Type RNA - Theca cells [nTPM]":"9.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.5","Single Cell Type RNA - Urothelial cells [nTPM]":"15.1"},{"Gene":"SLC25A38","Gene synonym":["FLJ20551"],"Ensembl":"ENSG00000144659","Gene description":"Solute carrier family 25 member 38","Uniprot":["Q96DW6"],"Chromosome":"3","Position":"39383370-39397351","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"73.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041027"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041027":"AB_10794403"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.58e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.29e-4"},"Tissue RNA - adipose tissue [nTPM]":"19.1","Tissue RNA - adrenal gland [nTPM]":"35.4","Tissue RNA - amygdala [nTPM]":"22.2","Tissue RNA - appendix [nTPM]":"18.8","Tissue RNA - basal ganglia [nTPM]":"23.3","Tissue RNA - bone marrow [nTPM]":"70.0","Tissue RNA - breast [nTPM]":"21.0","Tissue RNA - cerebellum [nTPM]":"25.9","Tissue RNA - cerebral cortex [nTPM]":"26.8","Tissue RNA - cervix [nTPM]":"23.8","Tissue RNA - choroid plexus [nTPM]":"33.6","Tissue RNA - colon [nTPM]":"28.1","Tissue RNA - duodenum [nTPM]":"25.3","Tissue RNA - endometrium 1 [nTPM]":"27.3","Tissue RNA - epididymis [nTPM]":"27.6","Tissue RNA - esophagus [nTPM]":"14.5","Tissue RNA - fallopian tube [nTPM]":"27.3","Tissue RNA - gallbladder [nTPM]":"19.4","Tissue RNA - heart muscle [nTPM]":"20.7","Tissue RNA - hippocampal formation [nTPM]":"22.9","Tissue RNA - hypothalamus [nTPM]":"26.3","Tissue RNA - kidney [nTPM]":"28.7","Tissue RNA - liver [nTPM]":"58.0","Tissue RNA - lung [nTPM]":"21.0","Tissue RNA - lymph node [nTPM]":"36.2","Tissue RNA - medulla oblongata [nTPM]":"24.2","Tissue RNA - midbrain [nTPM]":"24.1","Tissue RNA - ovary [nTPM]":"44.1","Tissue RNA - pancreas [nTPM]":"45.6","Tissue RNA - parathyroid gland [nTPM]":"38.7","Tissue RNA - pituitary gland [nTPM]":"30.7","Tissue RNA - placenta [nTPM]":"15.4","Tissue RNA - pons [nTPM]":"25.3","Tissue RNA - prostate [nTPM]":"29.2","Tissue RNA - rectum [nTPM]":"36.9","Tissue RNA - retina [nTPM]":"23.0","Tissue RNA - salivary gland [nTPM]":"22.5","Tissue RNA - seminal vesicle [nTPM]":"23.9","Tissue RNA - skeletal muscle [nTPM]":"48.2","Tissue RNA - skin 1 [nTPM]":"16.7","Tissue RNA - small intestine [nTPM]":"25.2","Tissue RNA - smooth muscle [nTPM]":"20.3","Tissue RNA - spinal cord [nTPM]":"22.6","Tissue RNA - spleen [nTPM]":"27.2","Tissue RNA - stomach 1 [nTPM]":"33.8","Tissue RNA - testis [nTPM]":"18.7","Tissue RNA - thalamus [nTPM]":"26.0","Tissue RNA - thymus [nTPM]":"33.6","Tissue RNA - thyroid gland [nTPM]":"52.0","Tissue RNA - tongue [nTPM]":"35.7","Tissue RNA - tonsil [nTPM]":"35.4","Tissue RNA - urinary bladder [nTPM]":"27.8","Tissue RNA - vagina [nTPM]":"19.1","Tissue RNA - white matter [nTPM]":"23.3","Cell RNA - A-431 [nTPM]":"24.3","Cell RNA - A549 [nTPM]":"38.3","Cell RNA - AF22 [nTPM]":"24.3","Cell RNA - AN3-CA [nTPM]":"41.2","Cell RNA - ASC diff [nTPM]":"56.4","Cell RNA - ASC TERT1 [nTPM]":"46.4","Cell RNA - BEWO [nTPM]":"30.8","Cell RNA - BJ [nTPM]":"33.6","Cell RNA - BJ hTERT+ [nTPM]":"46.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"48.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"43.7","Cell RNA - CACO-2 [nTPM]":"26.3","Cell RNA - CAPAN-2 [nTPM]":"5.6","Cell RNA - Daudi [nTPM]":"67.8","Cell RNA - EFO-21 [nTPM]":"19.6","Cell RNA - fHDF\/TERT166 [nTPM]":"31.6","Cell RNA - GAMG [nTPM]":"40.7","Cell RNA - HaCaT [nTPM]":"18.4","Cell RNA - HAP1 [nTPM]":"55.2","Cell RNA - HBEC3-KT [nTPM]":"40.1","Cell RNA - HBF TERT88 [nTPM]":"36.0","Cell RNA - HDLM-2 [nTPM]":"43.6","Cell RNA - HEK 293 [nTPM]":"45.0","Cell RNA - HEL [nTPM]":"52.0","Cell RNA - HeLa [nTPM]":"33.5","Cell RNA - Hep G2 [nTPM]":"40.2","Cell RNA - HHSteC [nTPM]":"75.6","Cell RNA - HL-60 [nTPM]":"37.7","Cell RNA - HMC-1 [nTPM]":"33.9","Cell RNA - HSkMC [nTPM]":"58.8","Cell RNA - hTCEpi [nTPM]":"46.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"46.2","Cell RNA - hTERT-HME1 [nTPM]":"93.2","Cell RNA - hTERT-RPE1 [nTPM]":"44.6","Cell RNA - HUVEC TERT2 [nTPM]":"31.5","Cell RNA - JURKAT [nTPM]":"52.8","Cell RNA - K-562 [nTPM]":"47.7","Cell RNA - Karpas-707 [nTPM]":"40.6","Cell RNA - LHCN-M2 [nTPM]":"36.4","Cell RNA - MCF7 [nTPM]":"35.2","Cell RNA - MOLT-4 [nTPM]":"44.7","Cell RNA - NB-4 [nTPM]":"67.0","Cell RNA - NTERA-2 [nTPM]":"66.2","Cell RNA - OE19 [nTPM]":"35.9","Cell RNA - PC-3 [nTPM]":"44.3","Cell RNA - REH [nTPM]":"16.2","Cell RNA - RH-30 [nTPM]":"26.4","Cell RNA - RPMI-8226 [nTPM]":"47.7","Cell RNA - RPTEC TERT1 [nTPM]":"37.5","Cell RNA - RT4 [nTPM]":"45.4","Cell RNA - SCLC-21H [nTPM]":"24.3","Cell RNA - SH-SY5Y [nTPM]":"31.1","Cell RNA - SiHa [nTPM]":"11.9","Cell RNA - SK-BR-3 [nTPM]":"65.9","Cell RNA - SK-MEL-30 [nTPM]":"34.0","Cell RNA - SuSa [nTPM]":"44.5","Cell RNA - T-47d [nTPM]":"33.5","Cell RNA - THP-1 [nTPM]":"35.0","Cell RNA - TIME [nTPM]":"26.9","Cell RNA - U-138 MG [nTPM]":"38.3","Cell RNA - U-2 OS [nTPM]":"26.4","Cell RNA - U-2197 [nTPM]":"56.2","Cell RNA - U-251 MG [nTPM]":"48.9","Cell RNA - U-266\/70 [nTPM]":"54.7","Cell RNA - U-266\/84 [nTPM]":"93.1","Cell RNA - U-698 [nTPM]":"41.9","Cell RNA - U-87 MG [nTPM]":"29.3","Cell RNA - U-937 [nTPM]":"48.3","Cell RNA - WM-115 [nTPM]":"24.7","Blood RNA - basophil [nTPM]":"30.7","Blood RNA - classical monocyte [nTPM]":"9.6","Blood RNA - eosinophil [nTPM]":"18.1","Blood RNA - gdT-cell [nTPM]":"38.8","Blood RNA - intermediate monocyte [nTPM]":"5.7","Blood RNA - MAIT T-cell [nTPM]":"44.7","Blood RNA - memory B-cell [nTPM]":"50.8","Blood RNA - memory CD4 T-cell [nTPM]":"39.1","Blood RNA - memory CD8 T-cell [nTPM]":"43.3","Blood RNA - myeloid DC [nTPM]":"14.9","Blood RNA - naive B-cell [nTPM]":"37.8","Blood RNA - naive CD4 T-cell [nTPM]":"41.7","Blood RNA - naive CD8 T-cell [nTPM]":"40.5","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"57.0","Blood RNA - non-classical monocyte [nTPM]":"8.4","Blood RNA - plasmacytoid DC [nTPM]":"18.5","Blood RNA - T-reg [nTPM]":"55.3","Blood RNA - total PBMC [nTPM]":"29.2","Brain RNA - amygdala [nTPM]":"22.2","Brain RNA - basal ganglia [nTPM]":"23.3","Brain RNA - cerebellum [nTPM]":"25.9","Brain RNA - cerebral cortex [nTPM]":"26.8","Brain RNA - hippocampal formation [nTPM]":"22.9","Brain RNA - hypothalamus [nTPM]":"26.3","Brain RNA - medulla oblongata [nTPM]":"24.2","Brain RNA - midbrain [nTPM]":"24.1","Brain RNA - pons [nTPM]":"25.3","Brain RNA - spinal cord [nTPM]":"22.6","Brain RNA - thalamus [nTPM]":"26.0","Brain RNA - white matter [nTPM]":"23.3","Single Cell Type RNA - Adipocytes [nTPM]":"10.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.4","Single Cell Type RNA - Astrocytes [nTPM]":"8.5","Single Cell Type RNA - B-cells [nTPM]":"35.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"28.5","Single Cell Type RNA - Bipolar cells [nTPM]":"13.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"22.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"9.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"35.2","Single Cell Type RNA - dendritic cells [nTPM]":"33.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"21.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"15.7","Single Cell Type RNA - Early spermatids [nTPM]":"6.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"26.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.3","Single Cell Type RNA - Endothelial cells [nTPM]":"11.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.6","Single Cell Type RNA - Erythroid cells [nTPM]":"73.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"32.6","Single Cell Type RNA - Fibroblasts [nTPM]":"13.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"38.5","Single Cell Type RNA - granulocytes [nTPM]":"22.2","Single Cell Type RNA - Granulosa cells [nTPM]":"24.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.7","Single Cell Type RNA - Hepatocytes [nTPM]":"27.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.2","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"25.6","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"7.0","Single Cell Type RNA - Langerhans cells [nTPM]":"13.7","Single Cell Type RNA - Late spermatids [nTPM]":"12.9","Single Cell Type RNA - Leydig cells [nTPM]":"15.5","Single Cell Type RNA - Macrophages [nTPM]":"9.8","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"11.2","Single Cell Type RNA - Muller glia cells [nTPM]":"18.9","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.4","Single Cell Type RNA - Paneth cells [nTPM]":"22.2","Single Cell Type RNA - Peritubular cells [nTPM]":"13.5","Single Cell Type RNA - Plasma cells [nTPM]":"23.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"31.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.9","Single Cell Type RNA - Spermatocytes [nTPM]":"11.0","Single Cell Type RNA - Spermatogonia [nTPM]":"7.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"19.4","Single Cell Type RNA - T-cells [nTPM]":"36.6","Single Cell Type RNA - Theca cells [nTPM]":"32.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.7","Single Cell Type RNA - Urothelial cells [nTPM]":"8.4"},{"Gene":"SLC25A42","Gene synonym":["MGC26694"],"Ensembl":"ENSG00000181035","Gene description":"Solute carrier family 25 member 42","Uniprot":["Q86VD7"],"Chromosome":"19","Position":"19063994-19113030","Protein class":["Disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"82.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"67.7","Hepatocytes":"52.1","Proximal tubular cells":"39.6","Rod photoreceptor cells":"41.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"gdT-cell":"2.7","MAIT T-cell":"1.4","memory B-cell":"3.3","memory CD4 T-cell":"1.5","memory CD8 T-cell":"2.4","naive B-cell":"3.2","naive CD4 T-cell":"1.0","naive CD8 T-cell":"1.4","NK-cell":"1.8","T-reg":"1.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"B-cells":"3.3","NK-cells":"1.8","T-cells":"2.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"K-562":"20.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049449"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA049449":"AB_2680772"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.04e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.11e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.5","Tissue RNA - adrenal gland [nTPM]":"7.5","Tissue RNA - amygdala [nTPM]":"17.2","Tissue RNA - appendix [nTPM]":"4.3","Tissue RNA - basal ganglia [nTPM]":"16.9","Tissue RNA - bone marrow [nTPM]":"8.3","Tissue RNA - breast [nTPM]":"7.9","Tissue RNA - cerebellum [nTPM]":"14.5","Tissue RNA - cerebral cortex [nTPM]":"18.3","Tissue RNA - cervix [nTPM]":"13.1","Tissue RNA - choroid plexus [nTPM]":"16.7","Tissue RNA - colon [nTPM]":"8.4","Tissue RNA - duodenum [nTPM]":"5.1","Tissue RNA - endometrium 1 [nTPM]":"10.1","Tissue RNA - epididymis [nTPM]":"3.7","Tissue RNA - esophagus [nTPM]":"5.2","Tissue RNA - fallopian tube [nTPM]":"12.5","Tissue RNA - gallbladder [nTPM]":"3.5","Tissue RNA - heart muscle [nTPM]":"15.8","Tissue RNA - hippocampal formation [nTPM]":"17.9","Tissue RNA - hypothalamus [nTPM]":"16.9","Tissue RNA - kidney [nTPM]":"34.1","Tissue RNA - liver [nTPM]":"82.0","Tissue RNA - lung [nTPM]":"6.6","Tissue RNA - lymph node [nTPM]":"9.0","Tissue RNA - medulla oblongata [nTPM]":"14.9","Tissue RNA - midbrain [nTPM]":"15.2","Tissue RNA - ovary [nTPM]":"16.9","Tissue RNA - pancreas [nTPM]":"11.3","Tissue RNA - parathyroid gland [nTPM]":"6.0","Tissue RNA - pituitary gland [nTPM]":"14.4","Tissue RNA - placenta [nTPM]":"2.6","Tissue RNA - pons [nTPM]":"14.7","Tissue RNA - prostate [nTPM]":"9.9","Tissue RNA - rectum [nTPM]":"2.4","Tissue RNA - retina [nTPM]":"8.4","Tissue RNA - salivary gland [nTPM]":"9.2","Tissue RNA - seminal vesicle [nTPM]":"5.2","Tissue RNA - skeletal muscle [nTPM]":"46.5","Tissue RNA - skin 1 [nTPM]":"6.7","Tissue RNA - small intestine [nTPM]":"9.3","Tissue RNA - smooth muscle [nTPM]":"4.9","Tissue RNA - spinal cord [nTPM]":"13.9","Tissue RNA - spleen [nTPM]":"12.7","Tissue RNA - stomach 1 [nTPM]":"8.3","Tissue RNA - testis [nTPM]":"7.0","Tissue RNA - thalamus [nTPM]":"18.0","Tissue RNA - thymus [nTPM]":"8.1","Tissue RNA - thyroid gland [nTPM]":"25.6","Tissue RNA - tongue [nTPM]":"32.6","Tissue RNA - tonsil [nTPM]":"7.5","Tissue RNA - urinary bladder [nTPM]":"9.6","Tissue RNA - vagina [nTPM]":"9.1","Tissue RNA - white matter [nTPM]":"13.9","Cell RNA - A-431 [nTPM]":"7.3","Cell RNA - A549 [nTPM]":"1.0","Cell RNA - AF22 [nTPM]":"1.8","Cell RNA - AN3-CA [nTPM]":"3.2","Cell RNA - ASC diff [nTPM]":"6.8","Cell RNA - ASC TERT1 [nTPM]":"5.6","Cell RNA - BEWO [nTPM]":"2.8","Cell RNA - BJ [nTPM]":"3.5","Cell RNA - BJ hTERT+ [nTPM]":"5.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.0","Cell RNA - CACO-2 [nTPM]":"1.4","Cell RNA - CAPAN-2 [nTPM]":"14.3","Cell RNA - Daudi [nTPM]":"5.2","Cell RNA - EFO-21 [nTPM]":"8.0","Cell RNA - fHDF\/TERT166 [nTPM]":"3.3","Cell RNA - GAMG [nTPM]":"5.3","Cell RNA - HaCaT [nTPM]":"1.3","Cell RNA - HAP1 [nTPM]":"3.7","Cell RNA - HBEC3-KT [nTPM]":"2.9","Cell RNA - HBF TERT88 [nTPM]":"3.0","Cell RNA - HDLM-2 [nTPM]":"1.3","Cell RNA - HEK 293 [nTPM]":"7.0","Cell RNA - HEL [nTPM]":"1.8","Cell RNA - HeLa [nTPM]":"2.0","Cell RNA - Hep G2 [nTPM]":"11.8","Cell RNA - HHSteC [nTPM]":"5.4","Cell RNA - HL-60 [nTPM]":"0.8","Cell RNA - HMC-1 [nTPM]":"3.6","Cell RNA - HSkMC [nTPM]":"5.6","Cell RNA - hTCEpi [nTPM]":"2.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.0","Cell RNA - hTERT-HME1 [nTPM]":"2.4","Cell RNA - hTERT-RPE1 [nTPM]":"4.3","Cell RNA - HUVEC TERT2 [nTPM]":"2.4","Cell RNA - JURKAT [nTPM]":"16.8","Cell RNA - K-562 [nTPM]":"20.9","Cell RNA - Karpas-707 [nTPM]":"9.2","Cell RNA - LHCN-M2 [nTPM]":"2.8","Cell RNA - MCF7 [nTPM]":"6.6","Cell RNA - MOLT-4 [nTPM]":"9.0","Cell RNA - NB-4 [nTPM]":"8.4","Cell RNA - NTERA-2 [nTPM]":"1.0","Cell RNA - OE19 [nTPM]":"2.0","Cell RNA - PC-3 [nTPM]":"7.4","Cell RNA - REH [nTPM]":"6.8","Cell RNA - RH-30 [nTPM]":"3.2","Cell RNA - RPMI-8226 [nTPM]":"10.2","Cell RNA - RPTEC TERT1 [nTPM]":"2.1","Cell RNA - RT4 [nTPM]":"1.3","Cell RNA - SCLC-21H [nTPM]":"2.0","Cell RNA - SH-SY5Y [nTPM]":"1.5","Cell RNA - SiHa [nTPM]":"3.7","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"1.6","Cell RNA - SuSa [nTPM]":"2.4","Cell RNA - T-47d [nTPM]":"6.5","Cell RNA - THP-1 [nTPM]":"4.1","Cell RNA - TIME [nTPM]":"2.2","Cell RNA - U-138 MG [nTPM]":"3.9","Cell RNA - U-2 OS [nTPM]":"2.2","Cell RNA - U-2197 [nTPM]":"8.2","Cell RNA - U-251 MG [nTPM]":"3.4","Cell RNA - U-266\/70 [nTPM]":"10.7","Cell RNA - U-266\/84 [nTPM]":"6.2","Cell RNA - U-698 [nTPM]":"4.1","Cell RNA - U-87 MG [nTPM]":"4.1","Cell RNA - U-937 [nTPM]":"11.2","Cell RNA - WM-115 [nTPM]":"2.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"2.7","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"1.4","Blood RNA - memory B-cell [nTPM]":"3.3","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"2.4","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"3.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.4","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"1.7","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"17.2","Brain RNA - basal ganglia [nTPM]":"16.9","Brain RNA - cerebellum [nTPM]":"14.5","Brain RNA - cerebral cortex [nTPM]":"18.3","Brain RNA - hippocampal formation [nTPM]":"17.9","Brain RNA - hypothalamus [nTPM]":"16.9","Brain RNA - medulla oblongata [nTPM]":"14.9","Brain RNA - midbrain [nTPM]":"15.2","Brain RNA - pons [nTPM]":"14.7","Brain RNA - spinal cord [nTPM]":"13.9","Brain RNA - thalamus [nTPM]":"18.0","Brain RNA - white matter [nTPM]":"13.9","Single Cell Type RNA - Adipocytes [nTPM]":"4.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.1","Single Cell Type RNA - Astrocytes [nTPM]":"12.4","Single Cell Type RNA - B-cells [nTPM]":"14.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"67.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"4.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.7","Single Cell Type RNA - dendritic cells [nTPM]":"16.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"1.5","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.4","Single Cell Type RNA - Endothelial cells [nTPM]":"4.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"13.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.8","Single Cell Type RNA - Fibroblasts [nTPM]":"5.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.6","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"8.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"52.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.8","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.8","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"1.9","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"1.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"1.3","Single Cell Type RNA - Muller glia cells [nTPM]":"12.5","Single Cell Type RNA - NK-cells [nTPM]":"32.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.5","Single Cell Type RNA - Paneth cells [nTPM]":"4.6","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"16.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"39.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"41.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.8","Single Cell Type RNA - Spermatocytes [nTPM]":"10.6","Single Cell Type RNA - Spermatogonia [nTPM]":"7.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.7","Single Cell Type RNA - T-cells [nTPM]":"10.9","Single Cell Type RNA - Theca cells [nTPM]":"8.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.1","Single Cell Type RNA - Urothelial cells [nTPM]":"1.7"},{"Gene":"SLC25A46","Gene synonym":[],"Ensembl":"ENSG00000164209","Gene description":"Solute carrier family 25 member 46","Uniprot":["Q96AG3"],"Chromosome":"5","Position":"110738136-110765161","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"238.9","Late spermatids":"448.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039601","HPA071582"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA039601":"AB_2676592","HPA071582":"AB_2686422"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.41e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.52e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Tissue RNA - adipose tissue [nTPM]":"22.9","Tissue RNA - adrenal gland [nTPM]":"15.9","Tissue RNA - amygdala [nTPM]":"10.4","Tissue RNA - appendix [nTPM]":"19.9","Tissue RNA - basal ganglia [nTPM]":"11.8","Tissue RNA - bone marrow [nTPM]":"17.6","Tissue RNA - breast [nTPM]":"16.4","Tissue RNA - cerebellum [nTPM]":"12.7","Tissue RNA - cerebral cortex [nTPM]":"16.7","Tissue RNA - cervix [nTPM]":"18.5","Tissue RNA - choroid plexus [nTPM]":"7.8","Tissue RNA - colon [nTPM]":"22.1","Tissue RNA - duodenum [nTPM]":"23.8","Tissue RNA - endometrium 1 [nTPM]":"14.7","Tissue RNA - epididymis [nTPM]":"10.5","Tissue RNA - esophagus [nTPM]":"21.2","Tissue RNA - fallopian tube [nTPM]":"10.7","Tissue RNA - gallbladder [nTPM]":"15.8","Tissue RNA - heart muscle [nTPM]":"31.1","Tissue RNA - hippocampal formation [nTPM]":"12.2","Tissue RNA - hypothalamus [nTPM]":"12.2","Tissue RNA - kidney [nTPM]":"29.7","Tissue RNA - liver [nTPM]":"30.0","Tissue RNA - lung [nTPM]":"16.7","Tissue RNA - lymph node [nTPM]":"22.5","Tissue RNA - medulla oblongata [nTPM]":"12.4","Tissue RNA - midbrain [nTPM]":"10.2","Tissue RNA - ovary [nTPM]":"11.7","Tissue RNA - pancreas [nTPM]":"15.4","Tissue RNA - parathyroid gland [nTPM]":"20.6","Tissue RNA - pituitary gland [nTPM]":"4.9","Tissue RNA - placenta [nTPM]":"17.0","Tissue RNA - pons [nTPM]":"13.2","Tissue RNA - prostate [nTPM]":"15.7","Tissue RNA - rectum [nTPM]":"21.6","Tissue RNA - retina [nTPM]":"18.8","Tissue RNA - salivary gland [nTPM]":"13.3","Tissue RNA - seminal vesicle [nTPM]":"16.0","Tissue RNA - skeletal muscle [nTPM]":"55.8","Tissue RNA - skin 1 [nTPM]":"14.9","Tissue RNA - small intestine [nTPM]":"20.9","Tissue RNA - smooth muscle [nTPM]":"20.8","Tissue RNA - spinal cord [nTPM]":"10.3","Tissue RNA - spleen [nTPM]":"15.7","Tissue RNA - stomach 1 [nTPM]":"20.1","Tissue RNA - testis [nTPM]":"21.9","Tissue RNA - thalamus [nTPM]":"11.2","Tissue RNA - thymus [nTPM]":"24.8","Tissue RNA - thyroid gland [nTPM]":"19.8","Tissue RNA - tongue [nTPM]":"60.2","Tissue RNA - tonsil [nTPM]":"26.8","Tissue RNA - urinary bladder [nTPM]":"19.0","Tissue RNA - vagina [nTPM]":"6.6","Tissue RNA - white matter [nTPM]":"14.1","Cell RNA - A-431 [nTPM]":"36.2","Cell RNA - A549 [nTPM]":"27.7","Cell RNA - AF22 [nTPM]":"25.7","Cell RNA - AN3-CA [nTPM]":"20.7","Cell RNA - ASC diff [nTPM]":"65.2","Cell RNA - ASC TERT1 [nTPM]":"60.2","Cell RNA - BEWO [nTPM]":"9.9","Cell RNA - BJ [nTPM]":"44.3","Cell RNA - BJ hTERT+ [nTPM]":"55.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"47.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"59.3","Cell RNA - CACO-2 [nTPM]":"37.6","Cell RNA - CAPAN-2 [nTPM]":"28.7","Cell RNA - Daudi [nTPM]":"96.8","Cell RNA - EFO-21 [nTPM]":"44.8","Cell RNA - fHDF\/TERT166 [nTPM]":"50.1","Cell RNA - GAMG [nTPM]":"61.9","Cell RNA - HaCaT [nTPM]":"29.6","Cell RNA - HAP1 [nTPM]":"41.0","Cell RNA - HBEC3-KT [nTPM]":"71.2","Cell RNA - HBF TERT88 [nTPM]":"54.3","Cell RNA - HDLM-2 [nTPM]":"61.8","Cell RNA - HEK 293 [nTPM]":"20.8","Cell RNA - HEL [nTPM]":"40.1","Cell RNA - HeLa [nTPM]":"35.2","Cell RNA - Hep G2 [nTPM]":"25.6","Cell RNA - HHSteC [nTPM]":"53.1","Cell RNA - HL-60 [nTPM]":"37.3","Cell RNA - HMC-1 [nTPM]":"40.2","Cell RNA - HSkMC [nTPM]":"49.9","Cell RNA - hTCEpi [nTPM]":"25.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"55.5","Cell RNA - hTERT-HME1 [nTPM]":"39.6","Cell RNA - hTERT-RPE1 [nTPM]":"29.5","Cell RNA - HUVEC TERT2 [nTPM]":"31.9","Cell RNA - JURKAT [nTPM]":"37.2","Cell RNA - K-562 [nTPM]":"31.4","Cell RNA - Karpas-707 [nTPM]":"56.4","Cell RNA - LHCN-M2 [nTPM]":"54.1","Cell RNA - MCF7 [nTPM]":"27.3","Cell RNA - MOLT-4 [nTPM]":"54.0","Cell RNA - NB-4 [nTPM]":"17.2","Cell RNA - NTERA-2 [nTPM]":"18.1","Cell RNA - OE19 [nTPM]":"25.7","Cell RNA - PC-3 [nTPM]":"24.7","Cell RNA - REH [nTPM]":"26.0","Cell RNA - RH-30 [nTPM]":"57.0","Cell RNA - RPMI-8226 [nTPM]":"71.5","Cell RNA - RPTEC TERT1 [nTPM]":"35.1","Cell RNA - RT4 [nTPM]":"39.2","Cell RNA - SCLC-21H [nTPM]":"46.7","Cell RNA - SH-SY5Y [nTPM]":"33.5","Cell RNA - SiHa [nTPM]":"37.7","Cell RNA - SK-BR-3 [nTPM]":"29.7","Cell RNA - SK-MEL-30 [nTPM]":"49.7","Cell RNA - SuSa [nTPM]":"23.7","Cell RNA - T-47d [nTPM]":"30.9","Cell RNA - THP-1 [nTPM]":"35.3","Cell RNA - TIME [nTPM]":"42.5","Cell RNA - U-138 MG [nTPM]":"43.6","Cell RNA - U-2 OS [nTPM]":"21.0","Cell RNA - U-2197 [nTPM]":"40.7","Cell RNA - U-251 MG [nTPM]":"54.4","Cell RNA - U-266\/70 [nTPM]":"111.8","Cell RNA - U-266\/84 [nTPM]":"76.2","Cell RNA - U-698 [nTPM]":"68.4","Cell RNA - U-87 MG [nTPM]":"48.0","Cell RNA - U-937 [nTPM]":"43.8","Cell RNA - WM-115 [nTPM]":"24.0","Blood RNA - basophil [nTPM]":"29.2","Blood RNA - classical monocyte [nTPM]":"16.0","Blood RNA - eosinophil [nTPM]":"13.2","Blood RNA - gdT-cell [nTPM]":"12.3","Blood RNA - intermediate monocyte [nTPM]":"19.0","Blood RNA - MAIT T-cell [nTPM]":"12.5","Blood RNA - memory B-cell [nTPM]":"14.4","Blood RNA - memory CD4 T-cell [nTPM]":"13.7","Blood RNA - memory CD8 T-cell [nTPM]":"12.9","Blood RNA - myeloid DC [nTPM]":"17.0","Blood RNA - naive B-cell [nTPM]":"14.5","Blood RNA - naive CD4 T-cell [nTPM]":"14.5","Blood RNA - naive CD8 T-cell [nTPM]":"14.8","Blood RNA - neutrophil [nTPM]":"6.6","Blood RNA - NK-cell [nTPM]":"20.9","Blood RNA - non-classical monocyte [nTPM]":"17.7","Blood RNA - plasmacytoid DC [nTPM]":"11.1","Blood RNA - T-reg [nTPM]":"18.2","Blood RNA - total PBMC [nTPM]":"17.4","Brain RNA - amygdala [nTPM]":"10.4","Brain RNA - basal ganglia [nTPM]":"11.8","Brain RNA - cerebellum [nTPM]":"12.7","Brain RNA - cerebral cortex [nTPM]":"16.7","Brain RNA - hippocampal formation [nTPM]":"12.2","Brain RNA - hypothalamus [nTPM]":"12.2","Brain RNA - medulla oblongata [nTPM]":"12.4","Brain RNA - midbrain [nTPM]":"10.2","Brain RNA - pons [nTPM]":"13.2","Brain RNA - spinal cord [nTPM]":"10.3","Brain RNA - thalamus [nTPM]":"11.2","Brain RNA - white matter [nTPM]":"14.1","Single Cell Type RNA - Adipocytes [nTPM]":"21.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"24.8","Single Cell Type RNA - Astrocytes [nTPM]":"40.8","Single Cell Type RNA - B-cells [nTPM]":"26.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"22.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.9","Single Cell Type RNA - Bipolar cells [nTPM]":"16.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"63.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"12.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"21.7","Single Cell Type RNA - dendritic cells [nTPM]":"18.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"34.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"18.1","Single Cell Type RNA - Early spermatids [nTPM]":"238.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.1","Single Cell Type RNA - Endothelial cells [nTPM]":"18.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"23.4","Single Cell Type RNA - Erythroid cells [nTPM]":"29.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"73.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.2","Single Cell Type RNA - Fibroblasts [nTPM]":"22.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"34.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.1","Single Cell Type RNA - granulocytes [nTPM]":"19.0","Single Cell Type RNA - Granulosa cells [nTPM]":"16.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.7","Single Cell Type RNA - Hepatocytes [nTPM]":"43.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"27.2","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"63.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.3","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"26.1","Single Cell Type RNA - Langerhans cells [nTPM]":"21.0","Single Cell Type RNA - Late spermatids [nTPM]":"448.2","Single Cell Type RNA - Leydig cells [nTPM]":"21.1","Single Cell Type RNA - Macrophages [nTPM]":"23.9","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"31.9","Single Cell Type RNA - monocytes [nTPM]":"28.1","Single Cell Type RNA - Muller glia cells [nTPM]":"21.9","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"49.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"91.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.9","Single Cell Type RNA - Paneth cells [nTPM]":"22.8","Single Cell Type RNA - Peritubular cells [nTPM]":"22.2","Single Cell Type RNA - Plasma cells [nTPM]":"73.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"26.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"41.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.1","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.6","Single Cell Type RNA - Spermatocytes [nTPM]":"23.3","Single Cell Type RNA - Spermatogonia [nTPM]":"14.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"30.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"26.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.5","Single Cell Type RNA - T-cells [nTPM]":"23.9","Single Cell Type RNA - Theca cells [nTPM]":"22.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.0","Single Cell Type RNA - Urothelial cells [nTPM]":"6.8"},{"Gene":"SLC26A1","Gene synonym":["EDM4","SAT-1"],"Ensembl":"ENSG00000145217","Gene description":"Solute carrier family 26 member 1","Uniprot":["Q9H2B4"],"Chromosome":"4","Position":"979073-993440","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Anion exchange","Antiport","Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"16.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"6.2","Excitatory neurons":"4.4","Hepatocytes":"10.4","Inhibitory neurons":"4.4","Oligodendrocyte precursor cells":"5.5","Proximal enterocytes":"6.4","Proximal tubular cells":"9.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"5.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"5.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"5.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"13.8","HMC-1":"8.7","T-47d":"9.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041654"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA041654":"AB_10796350"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.19e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-3"},"Tissue RNA - adipose tissue [nTPM]":"1.8","Tissue RNA - adrenal gland [nTPM]":"7.0","Tissue RNA - amygdala [nTPM]":"2.5","Tissue RNA - appendix [nTPM]":"1.5","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"1.4","Tissue RNA - breast [nTPM]":"2.7","Tissue RNA - cerebellum [nTPM]":"5.4","Tissue RNA - cerebral cortex [nTPM]":"3.3","Tissue RNA - cervix [nTPM]":"2.9","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"2.2","Tissue RNA - duodenum [nTPM]":"5.2","Tissue RNA - endometrium 1 [nTPM]":"2.1","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"1.6","Tissue RNA - fallopian tube [nTPM]":"2.1","Tissue RNA - gallbladder [nTPM]":"1.2","Tissue RNA - heart muscle [nTPM]":"1.2","Tissue RNA - hippocampal formation [nTPM]":"2.9","Tissue RNA - hypothalamus [nTPM]":"2.0","Tissue RNA - kidney [nTPM]":"5.8","Tissue RNA - liver [nTPM]":"16.8","Tissue RNA - lung [nTPM]":"2.0","Tissue RNA - lymph node [nTPM]":"1.5","Tissue RNA - medulla oblongata [nTPM]":"3.9","Tissue RNA - midbrain [nTPM]":"2.5","Tissue RNA - ovary [nTPM]":"2.5","Tissue RNA - pancreas [nTPM]":"3.3","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"3.3","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"3.2","Tissue RNA - prostate [nTPM]":"3.0","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"3.2","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"1.4","Tissue RNA - skin 1 [nTPM]":"2.5","Tissue RNA - small intestine [nTPM]":"4.5","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"2.4","Tissue RNA - stomach 1 [nTPM]":"3.1","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"2.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"3.2","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"1.8","Tissue RNA - vagina [nTPM]":"1.9","Tissue RNA - white matter [nTPM]":"2.6","Cell RNA - A-431 [nTPM]":"1.3","Cell RNA - A549 [nTPM]":"2.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"1.6","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"4.1","Cell RNA - BJ [nTPM]":"1.7","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"4.6","Cell RNA - CAPAN-2 [nTPM]":"2.7","Cell RNA - Daudi [nTPM]":"0.7","Cell RNA - EFO-21 [nTPM]":"2.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"1.6","Cell RNA - HaCaT [nTPM]":"1.3","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"2.7","Cell RNA - HEK 293 [nTPM]":"0.8","Cell RNA - HEL [nTPM]":"3.0","Cell RNA - HeLa [nTPM]":"3.3","Cell RNA - Hep G2 [nTPM]":"13.8","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"2.1","Cell RNA - HMC-1 [nTPM]":"8.7","Cell RNA - HSkMC [nTPM]":"0.5","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"1.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"2.6","Cell RNA - K-562 [nTPM]":"3.3","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.3","Cell RNA - MCF7 [nTPM]":"2.8","Cell RNA - MOLT-4 [nTPM]":"1.4","Cell RNA - NB-4 [nTPM]":"3.5","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"1.6","Cell RNA - PC-3 [nTPM]":"7.2","Cell RNA - REH [nTPM]":"6.9","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.7","Cell RNA - RT4 [nTPM]":"4.5","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"1.2","Cell RNA - SiHa [nTPM]":"0.4","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"1.2","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"9.1","Cell RNA - THP-1 [nTPM]":"1.3","Cell RNA - TIME [nTPM]":"2.0","Cell RNA - U-138 MG [nTPM]":"4.4","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"4.8","Cell RNA - U-251 MG [nTPM]":"1.3","Cell RNA - U-266\/70 [nTPM]":"6.5","Cell RNA - U-266\/84 [nTPM]":"3.2","Cell RNA - U-698 [nTPM]":"1.0","Cell RNA - U-87 MG [nTPM]":"1.4","Cell RNA - U-937 [nTPM]":"4.1","Cell RNA - WM-115 [nTPM]":"2.1","Blood RNA - basophil [nTPM]":"5.4","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"2.5","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"5.4","Brain RNA - cerebral cortex [nTPM]":"3.3","Brain RNA - hippocampal formation [nTPM]":"2.9","Brain RNA - hypothalamus [nTPM]":"2.0","Brain RNA - medulla oblongata [nTPM]":"3.9","Brain RNA - midbrain [nTPM]":"2.5","Brain RNA - pons [nTPM]":"3.2","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"2.0","Brain RNA - white matter [nTPM]":"2.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"6.2","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.6","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.8","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"10.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"1.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.7","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"SLC26A2","Gene synonym":["DTD","DTDST"],"Ensembl":"ENSG00000155850","Gene description":"Solute carrier family 26 member 2","Uniprot":["P50443"],"Chromosome":"5","Position":"149960758-149993455","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"intestine":"212.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Distal enterocytes":"2026.2","Glandular and luminal cells":"684.5","Syncytiotrophoblasts":"808.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"4.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"66.1","RPTEC TERT1":"151.7","TIME":"80.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041957","HPA058090"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA041957":"AB_10795646","HPA058090":"AB_2683602"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.29e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.66e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.27e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.2","Tissue RNA - adrenal gland [nTPM]":"30.7","Tissue RNA - amygdala [nTPM]":"2.2","Tissue RNA - appendix [nTPM]":"7.8","Tissue RNA - basal ganglia [nTPM]":"2.3","Tissue RNA - bone marrow [nTPM]":"2.5","Tissue RNA - breast [nTPM]":"9.2","Tissue RNA - cerebellum [nTPM]":"9.5","Tissue RNA - cerebral cortex [nTPM]":"3.8","Tissue RNA - cervix [nTPM]":"6.3","Tissue RNA - choroid plexus [nTPM]":"4.0","Tissue RNA - colon [nTPM]":"212.0","Tissue RNA - duodenum [nTPM]":"12.9","Tissue RNA - endometrium 1 [nTPM]":"9.3","Tissue RNA - epididymis [nTPM]":"22.8","Tissue RNA - esophagus [nTPM]":"10.7","Tissue RNA - fallopian tube [nTPM]":"5.0","Tissue RNA - gallbladder [nTPM]":"5.5","Tissue RNA - heart muscle [nTPM]":"2.8","Tissue RNA - hippocampal formation [nTPM]":"2.2","Tissue RNA - hypothalamus [nTPM]":"3.5","Tissue RNA - kidney [nTPM]":"4.9","Tissue RNA - liver [nTPM]":"1.7","Tissue RNA - lung [nTPM]":"7.3","Tissue RNA - lymph node [nTPM]":"4.0","Tissue RNA - medulla oblongata [nTPM]":"3.8","Tissue RNA - midbrain [nTPM]":"3.4","Tissue RNA - ovary [nTPM]":"4.8","Tissue RNA - pancreas [nTPM]":"3.4","Tissue RNA - parathyroid gland [nTPM]":"37.7","Tissue RNA - pituitary gland [nTPM]":"7.1","Tissue RNA - placenta [nTPM]":"34.0","Tissue RNA - pons [nTPM]":"3.5","Tissue RNA - prostate [nTPM]":"12.2","Tissue RNA - rectum [nTPM]":"189.6","Tissue RNA - retina [nTPM]":"20.8","Tissue RNA - salivary gland [nTPM]":"35.8","Tissue RNA - seminal vesicle [nTPM]":"18.4","Tissue RNA - skeletal muscle [nTPM]":"3.9","Tissue RNA - skin 1 [nTPM]":"7.8","Tissue RNA - small intestine [nTPM]":"16.1","Tissue RNA - smooth muscle [nTPM]":"9.3","Tissue RNA - spinal cord [nTPM]":"3.8","Tissue RNA - spleen [nTPM]":"3.7","Tissue RNA - stomach 1 [nTPM]":"3.3","Tissue RNA - testis [nTPM]":"4.2","Tissue RNA - thalamus [nTPM]":"3.9","Tissue RNA - thymus [nTPM]":"4.2","Tissue RNA - thyroid gland [nTPM]":"4.5","Tissue RNA - tongue [nTPM]":"3.7","Tissue RNA - tonsil [nTPM]":"5.9","Tissue RNA - urinary bladder [nTPM]":"4.7","Tissue RNA - vagina [nTPM]":"3.0","Tissue RNA - white matter [nTPM]":"3.4","Cell RNA - A-431 [nTPM]":"9.5","Cell RNA - A549 [nTPM]":"8.6","Cell RNA - AF22 [nTPM]":"10.5","Cell RNA - AN3-CA [nTPM]":"17.3","Cell RNA - ASC diff [nTPM]":"12.6","Cell RNA - ASC TERT1 [nTPM]":"8.8","Cell RNA - BEWO [nTPM]":"2.5","Cell RNA - BJ [nTPM]":"8.9","Cell RNA - BJ hTERT+ [nTPM]":"8.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.5","Cell RNA - CACO-2 [nTPM]":"44.7","Cell RNA - CAPAN-2 [nTPM]":"5.1","Cell RNA - Daudi [nTPM]":"7.4","Cell RNA - EFO-21 [nTPM]":"66.1","Cell RNA - fHDF\/TERT166 [nTPM]":"9.5","Cell RNA - GAMG [nTPM]":"16.8","Cell RNA - HaCaT [nTPM]":"6.8","Cell RNA - HAP1 [nTPM]":"10.0","Cell RNA - HBEC3-KT [nTPM]":"20.5","Cell RNA - HBF TERT88 [nTPM]":"12.4","Cell RNA - HDLM-2 [nTPM]":"6.0","Cell RNA - HEK 293 [nTPM]":"6.4","Cell RNA - HEL [nTPM]":"9.3","Cell RNA - HeLa [nTPM]":"6.7","Cell RNA - Hep G2 [nTPM]":"5.2","Cell RNA - HHSteC [nTPM]":"9.4","Cell RNA - HL-60 [nTPM]":"17.3","Cell RNA - HMC-1 [nTPM]":"15.2","Cell RNA - HSkMC [nTPM]":"9.8","Cell RNA - hTCEpi [nTPM]":"11.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.7","Cell RNA - hTERT-HME1 [nTPM]":"15.2","Cell RNA - hTERT-RPE1 [nTPM]":"17.3","Cell RNA - HUVEC TERT2 [nTPM]":"16.8","Cell RNA - JURKAT [nTPM]":"9.0","Cell RNA - K-562 [nTPM]":"2.4","Cell RNA - Karpas-707 [nTPM]":"7.1","Cell RNA - LHCN-M2 [nTPM]":"29.6","Cell RNA - MCF7 [nTPM]":"3.0","Cell RNA - MOLT-4 [nTPM]":"6.6","Cell RNA - NB-4 [nTPM]":"9.1","Cell RNA - NTERA-2 [nTPM]":"3.2","Cell RNA - OE19 [nTPM]":"3.2","Cell RNA - PC-3 [nTPM]":"13.5","Cell RNA - REH [nTPM]":"9.5","Cell RNA - RH-30 [nTPM]":"16.3","Cell RNA - RPMI-8226 [nTPM]":"3.9","Cell RNA - RPTEC TERT1 [nTPM]":"151.7","Cell RNA - RT4 [nTPM]":"41.6","Cell RNA - SCLC-21H [nTPM]":"3.2","Cell RNA - SH-SY5Y [nTPM]":"8.1","Cell RNA - SiHa [nTPM]":"15.6","Cell RNA - SK-BR-3 [nTPM]":"3.6","Cell RNA - SK-MEL-30 [nTPM]":"27.2","Cell RNA - SuSa [nTPM]":"8.1","Cell RNA - T-47d [nTPM]":"7.3","Cell RNA - THP-1 [nTPM]":"10.0","Cell RNA - TIME [nTPM]":"80.4","Cell RNA - U-138 MG [nTPM]":"16.0","Cell RNA - U-2 OS [nTPM]":"11.8","Cell RNA - U-2197 [nTPM]":"14.2","Cell RNA - U-251 MG [nTPM]":"10.7","Cell RNA - U-266\/70 [nTPM]":"5.2","Cell RNA - U-266\/84 [nTPM]":"7.3","Cell RNA - U-698 [nTPM]":"4.3","Cell RNA - U-87 MG [nTPM]":"14.7","Cell RNA - U-937 [nTPM]":"20.6","Cell RNA - WM-115 [nTPM]":"23.5","Blood RNA - basophil [nTPM]":"4.9","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.9","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"1.1","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"1.6","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"1.1","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"2.2","Brain RNA - basal ganglia [nTPM]":"2.3","Brain RNA - cerebellum [nTPM]":"9.5","Brain RNA - cerebral cortex [nTPM]":"3.8","Brain RNA - hippocampal formation [nTPM]":"2.2","Brain RNA - hypothalamus [nTPM]":"3.5","Brain RNA - medulla oblongata [nTPM]":"3.8","Brain RNA - midbrain [nTPM]":"3.4","Brain RNA - pons [nTPM]":"3.5","Brain RNA - spinal cord [nTPM]":"3.8","Brain RNA - thalamus [nTPM]":"3.9","Brain RNA - white matter [nTPM]":"3.4","Single Cell Type RNA - Adipocytes [nTPM]":"47.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.3","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"8.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"17.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"24.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"219.2","Single Cell Type RNA - dendritic cells [nTPM]":"11.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"2026.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.1","Single Cell Type RNA - Early spermatids [nTPM]":"32.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"237.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"92.3","Single Cell Type RNA - Endothelial cells [nTPM]":"29.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.1","Single Cell Type RNA - Erythroid cells [nTPM]":"16.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.7","Single Cell Type RNA - Fibroblasts [nTPM]":"21.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"684.5","Single Cell Type RNA - granulocytes [nTPM]":"90.0","Single Cell Type RNA - Granulosa cells [nTPM]":"29.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.2","Single Cell Type RNA - Hepatocytes [nTPM]":"2.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.4","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"52.5","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"15.3","Single Cell Type RNA - Langerhans cells [nTPM]":"11.8","Single Cell Type RNA - Late spermatids [nTPM]":"15.7","Single Cell Type RNA - Leydig cells [nTPM]":"17.4","Single Cell Type RNA - Macrophages [nTPM]":"17.4","Single Cell Type RNA - Melanocytes [nTPM]":"90.7","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"19.6","Single Cell Type RNA - Muller glia cells [nTPM]":"15.2","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.1","Single Cell Type RNA - Paneth cells [nTPM]":"177.4","Single Cell Type RNA - Peritubular cells [nTPM]":"12.4","Single Cell Type RNA - Plasma cells [nTPM]":"15.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"91.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"26.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"84.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.9","Single Cell Type RNA - Spermatocytes [nTPM]":"8.7","Single Cell Type RNA - Spermatogonia [nTPM]":"11.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"73.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"808.9","Single Cell Type RNA - T-cells [nTPM]":"14.0","Single Cell Type RNA - Theca cells [nTPM]":"26.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"208.9","Single Cell Type RNA - Urothelial cells [nTPM]":"5.5"},{"Gene":"SLC26A3","Gene synonym":["CLD","DRA"],"Ensembl":"ENSG00000091138","Gene description":"Solute carrier family 26 member 3","Uniprot":["P40879"],"Chromosome":"7","Position":"107765467-107803225","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"intestine":"1120.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Distal enterocytes":"2328.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"14","RNA cancer specific FPKM":{"colorectal cancer":"52.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RPMI-8226":"2.9"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036055"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036055":"AB_10602401"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-3"},"Tissue RNA - adipose tissue [nTPM]":"1.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"19.7","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"59.5","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1120.4","Tissue RNA - duodenum [nTPM]":"576.9","Tissue RNA - endometrium 1 [nTPM]":"0.9","Tissue RNA - epididymis [nTPM]":"15.3","Tissue RNA - esophagus [nTPM]":"0.5","Tissue RNA - fallopian tube [nTPM]":"0.8","Tissue RNA - gallbladder [nTPM]":"17.8","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.8","Tissue RNA - liver [nTPM]":"0.5","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"1.1","Tissue RNA - rectum [nTPM]":"878.8","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"129.9","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"118.5","Tissue RNA - smooth muscle [nTPM]":"15.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"1.3","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.8","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.7","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"2.9","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"165.9","Single Cell Type RNA - B-cells [nTPM]":"4.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"51.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"41.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"34.3","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"2328.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"6.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.3","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"110.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"26.7","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"114.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"32.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"89.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"101.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"182.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"503.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"388.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"2.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"86.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"SLC26A4","Gene synonym":["DFNB4","PDS"],"Ensembl":"ENSG00000091137","Gene description":"Solute carrier family 26 member 4","Uniprot":["O43511"],"Chromosome":"7","Position":"107660828-107717809","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"22","RNA tissue specific nTPM":{"thyroid gland":"263.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Club cells":"19.0","Excitatory neurons":"29.3","Inhibitory neurons":"53.9","Ionocytes":"54.9","Prostatic glandular cells":"17.3","Urothelial cells":"19.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"thyroid cancer":"37.6"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"88","RNA brain regional specific nTPM":{"amygdala":"4.0","basal ganglia":"10.2","cerebral cortex":"11.8","hippocampal formation":"8.8"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"naive B-cell":"1.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"B-cells":"1.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"1.6","hTERT-RPE1":"3.7","LHCN-M2":"2.1"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"hippocampal formation":"9.7"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"hippocampal formation":"4.8"},"Antibody":["HPA042860"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042860":"AB_10796680"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"4.0","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"10.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.8","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"11.8","Tissue RNA - cervix [nTPM]":"1.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.5","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.6","Tissue RNA - hippocampal formation [nTPM]":"8.8","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"6.4","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.5","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"3.9","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"3.8","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.7","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"263.7","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"1.5","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.3","Cell RNA - ASC TERT1 [nTPM]":"0.6","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"1.6","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"3.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"2.1","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.5","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.8","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"1.3","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.0","Brain RNA - basal ganglia [nTPM]":"10.2","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"11.8","Brain RNA - hippocampal formation [nTPM]":"8.8","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"1.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.7","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"6.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"19.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"3.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"4.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.3","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"29.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.8","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"53.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"54.9","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"2.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"1.2","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.6","Single Cell Type RNA - Spermatocytes [nTPM]":"2.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.7","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.5","Single Cell Type RNA - Urothelial cells [nTPM]":"19.9"},{"Gene":"SLC26A5","Gene synonym":["DFNB61","PRES"],"Ensembl":"ENSG00000170615","Gene description":"Solute carrier family 26 member 5","Uniprot":["P58743"],"Chromosome":"7","Position":"103352730-103446207","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Cell shape","Hearing"],"Molecular function":["Motor protein"],"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"2.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"6.4","Astrocytes":"5.5","Excitatory neurons":"4.1","Gastric mucus-secreting cells":"7.1","Hepatic stellate cells":"5.3","Inhibitory neurons":"3.5","Microglial cells":"6.5","Oligodendrocytes":"4.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"2.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"basal ganglia":"10.4"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.7","Tissue RNA - cerebellum [nTPM]":"2.2","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.4","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"0.5","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.4","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.6","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.5","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"2.2","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.4","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"0.5","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.4","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.6","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"SLC26A8","Gene synonym":[],"Ensembl":"ENSG00000112053","Gene description":"Solute carrier family 26 member 8","Uniprot":["Q96RN1"],"Chromosome":"6","Position":"35943516-36024868","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Anion exchange","Differentiation","Ion transport","Meiosis","Spermatogenesis","Transport"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"testis":"44.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"54.1","Excitatory neurons":"15.8","Inhibitory neurons":"12.1","Late spermatids":"12.0","Spermatocytes":"64.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"11","RNA blood cell specific nTPM":{"neutrophil":"2.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"granulocytes":"2.3"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038081"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038081":"AB_10670653"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-8"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.6","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"4.8","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.8","Tissue RNA - cerebral cortex [nTPM]":"0.8","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.9","Tissue RNA - midbrain [nTPM]":"0.6","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"1.1","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"1.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"44.0","Tissue RNA - thalamus [nTPM]":"0.9","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"2.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.6","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"0.8","Brain RNA - cerebral cortex [nTPM]":"0.8","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"0.9","Brain RNA - midbrain [nTPM]":"0.6","Brain RNA - pons [nTPM]":"1.1","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"0.9","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"54.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.2","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"12.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"64.8","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"SLC27A4","Gene synonym":["ACSVL4","FATP4"],"Ensembl":"ENSG00000167114","Gene description":"Solute carrier family 27 member 4","Uniprot":["Q6P1M0"],"Chromosome":"9","Position":"128340527-128361470","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Fatty acid metabolism","Lipid metabolism","Lipid transport","Transport"],"Molecular function":["Ligase"],"Disease involvement":["Disease variant","Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"53.7","Proximal enterocytes":"100.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007293","CAB009771"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB009771":"AB_2270540","HPA007293":"AB_1857062"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.61e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-3"},"Tissue RNA - adipose tissue [nTPM]":"11.4","Tissue RNA - adrenal gland [nTPM]":"14.7","Tissue RNA - amygdala [nTPM]":"22.5","Tissue RNA - appendix [nTPM]":"8.5","Tissue RNA - basal ganglia [nTPM]":"23.7","Tissue RNA - bone marrow [nTPM]":"2.7","Tissue RNA - breast [nTPM]":"11.6","Tissue RNA - cerebellum [nTPM]":"25.4","Tissue RNA - cerebral cortex [nTPM]":"30.3","Tissue RNA - cervix [nTPM]":"17.2","Tissue RNA - choroid plexus [nTPM]":"12.4","Tissue RNA - colon [nTPM]":"22.8","Tissue RNA - duodenum [nTPM]":"66.9","Tissue RNA - endometrium 1 [nTPM]":"14.4","Tissue RNA - epididymis [nTPM]":"6.3","Tissue RNA - esophagus [nTPM]":"61.8","Tissue RNA - fallopian tube [nTPM]":"10.4","Tissue RNA - gallbladder [nTPM]":"7.3","Tissue RNA - heart muscle [nTPM]":"20.4","Tissue RNA - hippocampal formation [nTPM]":"22.7","Tissue RNA - hypothalamus [nTPM]":"25.9","Tissue RNA - kidney [nTPM]":"28.8","Tissue RNA - liver [nTPM]":"40.0","Tissue RNA - lung [nTPM]":"11.8","Tissue RNA - lymph node [nTPM]":"6.4","Tissue RNA - medulla oblongata [nTPM]":"29.4","Tissue RNA - midbrain [nTPM]":"23.9","Tissue RNA - ovary [nTPM]":"8.3","Tissue RNA - pancreas [nTPM]":"21.6","Tissue RNA - parathyroid gland [nTPM]":"15.5","Tissue RNA - pituitary gland [nTPM]":"12.1","Tissue RNA - placenta [nTPM]":"5.6","Tissue RNA - pons [nTPM]":"28.8","Tissue RNA - prostate [nTPM]":"13.1","Tissue RNA - rectum [nTPM]":"9.4","Tissue RNA - retina [nTPM]":"6.8","Tissue RNA - salivary gland [nTPM]":"16.4","Tissue RNA - seminal vesicle [nTPM]":"7.5","Tissue RNA - skeletal muscle [nTPM]":"16.1","Tissue RNA - skin 1 [nTPM]":"41.8","Tissue RNA - small intestine [nTPM]":"41.1","Tissue RNA - smooth muscle [nTPM]":"9.3","Tissue RNA - spinal cord [nTPM]":"19.7","Tissue RNA - spleen [nTPM]":"11.6","Tissue RNA - stomach 1 [nTPM]":"16.4","Tissue RNA - testis [nTPM]":"25.8","Tissue RNA - thalamus [nTPM]":"27.1","Tissue RNA - thymus [nTPM]":"5.8","Tissue RNA - thyroid gland [nTPM]":"15.5","Tissue RNA - tongue [nTPM]":"6.2","Tissue RNA - tonsil [nTPM]":"9.6","Tissue RNA - urinary bladder [nTPM]":"15.5","Tissue RNA - vagina [nTPM]":"23.5","Tissue RNA - white matter [nTPM]":"24.1","Cell RNA - A-431 [nTPM]":"20.8","Cell RNA - A549 [nTPM]":"41.8","Cell RNA - AF22 [nTPM]":"21.1","Cell RNA - AN3-CA [nTPM]":"28.1","Cell RNA - ASC diff [nTPM]":"31.5","Cell RNA - ASC TERT1 [nTPM]":"9.8","Cell RNA - BEWO [nTPM]":"23.3","Cell RNA - BJ [nTPM]":"16.7","Cell RNA - BJ hTERT+ [nTPM]":"11.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.5","Cell RNA - CACO-2 [nTPM]":"30.1","Cell RNA - CAPAN-2 [nTPM]":"20.7","Cell RNA - Daudi [nTPM]":"19.1","Cell RNA - EFO-21 [nTPM]":"13.5","Cell RNA - fHDF\/TERT166 [nTPM]":"19.8","Cell RNA - GAMG [nTPM]":"24.8","Cell RNA - HaCaT [nTPM]":"70.6","Cell RNA - HAP1 [nTPM]":"25.5","Cell RNA - HBEC3-KT [nTPM]":"20.7","Cell RNA - HBF TERT88 [nTPM]":"6.7","Cell RNA - HDLM-2 [nTPM]":"19.5","Cell RNA - HEK 293 [nTPM]":"37.2","Cell RNA - HEL [nTPM]":"11.4","Cell RNA - HeLa [nTPM]":"35.6","Cell RNA - Hep G2 [nTPM]":"28.5","Cell RNA - HHSteC [nTPM]":"17.1","Cell RNA - HL-60 [nTPM]":"21.0","Cell RNA - HMC-1 [nTPM]":"17.8","Cell RNA - HSkMC [nTPM]":"12.7","Cell RNA - hTCEpi [nTPM]":"29.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.2","Cell RNA - hTERT-HME1 [nTPM]":"17.0","Cell RNA - hTERT-RPE1 [nTPM]":"9.4","Cell RNA - HUVEC TERT2 [nTPM]":"23.1","Cell RNA - JURKAT [nTPM]":"26.3","Cell RNA - K-562 [nTPM]":"27.5","Cell RNA - Karpas-707 [nTPM]":"13.7","Cell RNA - LHCN-M2 [nTPM]":"20.2","Cell RNA - MCF7 [nTPM]":"56.2","Cell RNA - MOLT-4 [nTPM]":"26.0","Cell RNA - NB-4 [nTPM]":"22.7","Cell RNA - NTERA-2 [nTPM]":"9.2","Cell RNA - OE19 [nTPM]":"51.6","Cell RNA - PC-3 [nTPM]":"63.0","Cell RNA - REH [nTPM]":"30.4","Cell RNA - RH-30 [nTPM]":"19.6","Cell RNA - RPMI-8226 [nTPM]":"36.4","Cell RNA - RPTEC TERT1 [nTPM]":"38.1","Cell RNA - RT4 [nTPM]":"32.0","Cell RNA - SCLC-21H [nTPM]":"34.8","Cell RNA - SH-SY5Y [nTPM]":"19.2","Cell RNA - SiHa [nTPM]":"27.6","Cell RNA - SK-BR-3 [nTPM]":"57.0","Cell RNA - SK-MEL-30 [nTPM]":"20.3","Cell RNA - SuSa [nTPM]":"11.3","Cell RNA - T-47d [nTPM]":"26.7","Cell RNA - THP-1 [nTPM]":"8.8","Cell RNA - TIME [nTPM]":"32.4","Cell RNA - U-138 MG [nTPM]":"23.7","Cell RNA - U-2 OS [nTPM]":"22.9","Cell RNA - U-2197 [nTPM]":"26.6","Cell RNA - U-251 MG [nTPM]":"22.0","Cell RNA - U-266\/70 [nTPM]":"11.4","Cell RNA - U-266\/84 [nTPM]":"17.4","Cell RNA - U-698 [nTPM]":"6.5","Cell RNA - U-87 MG [nTPM]":"24.3","Cell RNA - U-937 [nTPM]":"13.0","Cell RNA - WM-115 [nTPM]":"27.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.5","Blood RNA - eosinophil [nTPM]":"1.7","Blood RNA - gdT-cell [nTPM]":"4.7","Blood RNA - intermediate monocyte [nTPM]":"3.3","Blood RNA - MAIT T-cell [nTPM]":"3.4","Blood RNA - memory B-cell [nTPM]":"2.1","Blood RNA - memory CD4 T-cell [nTPM]":"2.9","Blood RNA - memory CD8 T-cell [nTPM]":"3.6","Blood RNA - myeloid DC [nTPM]":"4.4","Blood RNA - naive B-cell [nTPM]":"0.9","Blood RNA - naive CD4 T-cell [nTPM]":"2.3","Blood RNA - naive CD8 T-cell [nTPM]":"2.4","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"1.4","Blood RNA - non-classical monocyte [nTPM]":"4.3","Blood RNA - plasmacytoid DC [nTPM]":"3.9","Blood RNA - T-reg [nTPM]":"2.2","Blood RNA - total PBMC [nTPM]":"2.4","Brain RNA - amygdala [nTPM]":"22.5","Brain RNA - basal ganglia [nTPM]":"23.7","Brain RNA - cerebellum [nTPM]":"25.4","Brain RNA - cerebral cortex [nTPM]":"30.3","Brain RNA - hippocampal formation [nTPM]":"22.7","Brain RNA - hypothalamus [nTPM]":"25.9","Brain RNA - medulla oblongata [nTPM]":"29.4","Brain RNA - midbrain [nTPM]":"23.9","Brain RNA - pons [nTPM]":"28.8","Brain RNA - spinal cord [nTPM]":"19.7","Brain RNA - thalamus [nTPM]":"27.1","Brain RNA - white matter [nTPM]":"24.1","Single Cell Type RNA - Adipocytes [nTPM]":"4.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"12.7","Single Cell Type RNA - B-cells [nTPM]":"2.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"9.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"2.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.1","Single Cell Type RNA - dendritic cells [nTPM]":"2.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"53.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"13.1","Single Cell Type RNA - Early spermatids [nTPM]":"4.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.2","Single Cell Type RNA - Endothelial cells [nTPM]":"5.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"4.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"27.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.8","Single Cell Type RNA - Fibroblasts [nTPM]":"3.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.3","Single Cell Type RNA - granulocytes [nTPM]":"8.9","Single Cell Type RNA - Granulosa cells [nTPM]":"5.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"20.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.3","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"29.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.6","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"6.1","Single Cell Type RNA - Langerhans cells [nTPM]":"1.9","Single Cell Type RNA - Late spermatids [nTPM]":"5.4","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"5.4","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"10.0","Single Cell Type RNA - Muller glia cells [nTPM]":"5.0","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"26.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"26.4","Single Cell Type RNA - Paneth cells [nTPM]":"30.0","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"3.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"100.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.4","Single Cell Type RNA - Spermatocytes [nTPM]":"11.8","Single Cell Type RNA - Spermatogonia [nTPM]":"7.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.2","Single Cell Type RNA - T-cells [nTPM]":"2.4","Single Cell Type RNA - Theca cells [nTPM]":"7.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"25.7","Single Cell Type RNA - Urothelial cells [nTPM]":"2.8"},{"Gene":"SLC28A1","Gene synonym":["CNT1"],"Ensembl":"ENSG00000156222","Gene description":"Solute carrier family 28 member 1","Uniprot":["O00337"],"Chromosome":"15","Position":"84884654-84945798","Protein class":["Disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"21","RNA tissue specific nTPM":{"intestine":"49.1","kidney":"48.2","liver":"111.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Hepatocytes":"38.6","Hofbauer cells":"54.3","Proximal enterocytes":"86.9","Proximal tubular cells":"93.4"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"63","RNA cancer specific FPKM":{"liver cancer":"10.9","renal cancer":"33.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019551","HPA056247"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear speckles","Cytosol"],"Antibody RRID":{"HPA019551":"AB_2670187","HPA056247":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.72e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"37.9","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.7","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"1.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"48.2","Tissue RNA - liver [nTPM]":"111.3","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"0.9","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"1.2","Tissue RNA - pons [nTPM]":"0.7","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"1.5","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"49.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.4","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"3.3","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.7","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.9","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.7","Brain RNA - spinal cord [nTPM]":"0.4","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"3.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"38.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"54.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"2.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"86.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"93.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"SLC29A3","Gene synonym":["ENT3","FLJ11160"],"Ensembl":"ENSG00000198246","Gene description":"Solute carrier family 29 member 3","Uniprot":["Q9BZD2"],"Chromosome":"10","Position":"71319259-71381423","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"46.1","Extravillous trophoblasts":"45.3","Hofbauer cells":"34.7","Syncytiotrophoblasts":"31.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"31.8","Hep G2":"35.9","RT4":"29.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046085","HPA054976","HPA057905"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA046085":"AB_2679531","HPA054976":"AB_2682659","HPA057905":"AB_2683550"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.07e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.53e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.16e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-3"},"Tissue RNA - adipose tissue [nTPM]":"4.7","Tissue RNA - adrenal gland [nTPM]":"2.6","Tissue RNA - amygdala [nTPM]":"3.1","Tissue RNA - appendix [nTPM]":"4.1","Tissue RNA - basal ganglia [nTPM]":"3.9","Tissue RNA - bone marrow [nTPM]":"1.1","Tissue RNA - breast [nTPM]":"4.8","Tissue RNA - cerebellum [nTPM]":"3.7","Tissue RNA - cerebral cortex [nTPM]":"3.7","Tissue RNA - cervix [nTPM]":"7.3","Tissue RNA - choroid plexus [nTPM]":"2.7","Tissue RNA - colon [nTPM]":"4.4","Tissue RNA - duodenum [nTPM]":"2.1","Tissue RNA - endometrium 1 [nTPM]":"6.8","Tissue RNA - epididymis [nTPM]":"2.5","Tissue RNA - esophagus [nTPM]":"2.2","Tissue RNA - fallopian tube [nTPM]":"5.8","Tissue RNA - gallbladder [nTPM]":"4.4","Tissue RNA - heart muscle [nTPM]":"2.4","Tissue RNA - hippocampal formation [nTPM]":"3.0","Tissue RNA - hypothalamus [nTPM]":"3.6","Tissue RNA - kidney [nTPM]":"2.5","Tissue RNA - liver [nTPM]":"9.4","Tissue RNA - lung [nTPM]":"6.7","Tissue RNA - lymph node [nTPM]":"7.1","Tissue RNA - medulla oblongata [nTPM]":"4.7","Tissue RNA - midbrain [nTPM]":"3.7","Tissue RNA - ovary [nTPM]":"9.7","Tissue RNA - pancreas [nTPM]":"5.2","Tissue RNA - parathyroid gland [nTPM]":"3.5","Tissue RNA - pituitary gland [nTPM]":"1.7","Tissue RNA - placenta [nTPM]":"11.2","Tissue RNA - pons [nTPM]":"4.2","Tissue RNA - prostate [nTPM]":"5.1","Tissue RNA - rectum [nTPM]":"3.5","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"4.9","Tissue RNA - seminal vesicle [nTPM]":"2.9","Tissue RNA - skeletal muscle [nTPM]":"1.4","Tissue RNA - skin 1 [nTPM]":"2.6","Tissue RNA - small intestine [nTPM]":"3.7","Tissue RNA - smooth muscle [nTPM]":"5.1","Tissue RNA - spinal cord [nTPM]":"4.2","Tissue RNA - spleen [nTPM]":"6.5","Tissue RNA - stomach 1 [nTPM]":"6.1","Tissue RNA - testis [nTPM]":"3.7","Tissue RNA - thalamus [nTPM]":"4.4","Tissue RNA - thymus [nTPM]":"3.7","Tissue RNA - thyroid gland [nTPM]":"3.8","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"3.8","Tissue RNA - urinary bladder [nTPM]":"9.8","Tissue RNA - vagina [nTPM]":"4.4","Tissue RNA - white matter [nTPM]":"5.0","Cell RNA - A-431 [nTPM]":"2.1","Cell RNA - A549 [nTPM]":"12.3","Cell RNA - AF22 [nTPM]":"1.8","Cell RNA - AN3-CA [nTPM]":"7.8","Cell RNA - ASC diff [nTPM]":"6.8","Cell RNA - ASC TERT1 [nTPM]":"5.3","Cell RNA - BEWO [nTPM]":"31.8","Cell RNA - BJ [nTPM]":"2.3","Cell RNA - BJ hTERT+ [nTPM]":"2.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"13.8","Cell RNA - CAPAN-2 [nTPM]":"8.8","Cell RNA - Daudi [nTPM]":"7.4","Cell RNA - EFO-21 [nTPM]":"6.4","Cell RNA - fHDF\/TERT166 [nTPM]":"4.7","Cell RNA - GAMG [nTPM]":"3.2","Cell RNA - HaCaT [nTPM]":"18.3","Cell RNA - HAP1 [nTPM]":"5.7","Cell RNA - HBEC3-KT [nTPM]":"2.9","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"5.6","Cell RNA - HEK 293 [nTPM]":"5.6","Cell RNA - HEL [nTPM]":"2.2","Cell RNA - HeLa [nTPM]":"1.0","Cell RNA - Hep G2 [nTPM]":"35.9","Cell RNA - HHSteC [nTPM]":"3.3","Cell RNA - HL-60 [nTPM]":"1.8","Cell RNA - HMC-1 [nTPM]":"4.5","Cell RNA - HSkMC [nTPM]":"5.2","Cell RNA - hTCEpi [nTPM]":"12.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.3","Cell RNA - hTERT-HME1 [nTPM]":"0.6","Cell RNA - hTERT-RPE1 [nTPM]":"1.5","Cell RNA - HUVEC TERT2 [nTPM]":"3.2","Cell RNA - JURKAT [nTPM]":"8.5","Cell RNA - K-562 [nTPM]":"6.5","Cell RNA - Karpas-707 [nTPM]":"6.8","Cell RNA - LHCN-M2 [nTPM]":"0.9","Cell RNA - MCF7 [nTPM]":"19.1","Cell RNA - MOLT-4 [nTPM]":"4.2","Cell RNA - NB-4 [nTPM]":"3.8","Cell RNA - NTERA-2 [nTPM]":"4.2","Cell RNA - OE19 [nTPM]":"19.2","Cell RNA - PC-3 [nTPM]":"4.5","Cell RNA - REH [nTPM]":"5.7","Cell RNA - RH-30 [nTPM]":"0.6","Cell RNA - RPMI-8226 [nTPM]":"5.9","Cell RNA - RPTEC TERT1 [nTPM]":"2.3","Cell RNA - RT4 [nTPM]":"29.5","Cell RNA - SCLC-21H [nTPM]":"8.5","Cell RNA - SH-SY5Y [nTPM]":"9.6","Cell RNA - SiHa [nTPM]":"6.4","Cell RNA - SK-BR-3 [nTPM]":"20.3","Cell RNA - SK-MEL-30 [nTPM]":"1.7","Cell RNA - SuSa [nTPM]":"5.2","Cell RNA - T-47d [nTPM]":"3.2","Cell RNA - THP-1 [nTPM]":"4.0","Cell RNA - TIME [nTPM]":"5.2","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"3.8","Cell RNA - U-2197 [nTPM]":"2.3","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"1.8","Cell RNA - U-266\/84 [nTPM]":"3.1","Cell RNA - U-698 [nTPM]":"4.0","Cell RNA - U-87 MG [nTPM]":"7.6","Cell RNA - U-937 [nTPM]":"24.0","Cell RNA - WM-115 [nTPM]":"1.3","Blood RNA - basophil [nTPM]":"4.2","Blood RNA - classical monocyte [nTPM]":"19.3","Blood RNA - eosinophil [nTPM]":"2.2","Blood RNA - gdT-cell [nTPM]":"5.4","Blood RNA - intermediate monocyte [nTPM]":"15.3","Blood RNA - MAIT T-cell [nTPM]":"4.6","Blood RNA - memory B-cell [nTPM]":"4.9","Blood RNA - memory CD4 T-cell [nTPM]":"4.5","Blood RNA - memory CD8 T-cell [nTPM]":"5.1","Blood RNA - myeloid DC [nTPM]":"29.1","Blood RNA - naive B-cell [nTPM]":"1.9","Blood RNA - naive CD4 T-cell [nTPM]":"3.5","Blood RNA - naive CD8 T-cell [nTPM]":"5.0","Blood RNA - neutrophil [nTPM]":"1.5","Blood RNA - NK-cell [nTPM]":"9.4","Blood RNA - non-classical monocyte [nTPM]":"10.3","Blood RNA - plasmacytoid DC [nTPM]":"20.2","Blood RNA - T-reg [nTPM]":"5.5","Blood RNA - total PBMC [nTPM]":"9.5","Brain RNA - amygdala [nTPM]":"3.1","Brain RNA - basal ganglia [nTPM]":"3.9","Brain RNA - cerebellum [nTPM]":"3.7","Brain RNA - cerebral cortex [nTPM]":"3.7","Brain RNA - hippocampal formation [nTPM]":"3.0","Brain RNA - hypothalamus [nTPM]":"3.6","Brain RNA - medulla oblongata [nTPM]":"4.7","Brain RNA - midbrain [nTPM]":"3.7","Brain RNA - pons [nTPM]":"4.2","Brain RNA - spinal cord [nTPM]":"4.2","Brain RNA - thalamus [nTPM]":"4.4","Brain RNA - white matter [nTPM]":"5.0","Single Cell Type RNA - Adipocytes [nTPM]":"2.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"3.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"2.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"3.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"46.1","Single Cell Type RNA - dendritic cells [nTPM]":"6.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.1","Single Cell Type RNA - Early spermatids [nTPM]":"3.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.2","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"4.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"45.3","Single Cell Type RNA - Fibroblasts [nTPM]":"4.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.4","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"10.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"5.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"34.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.5","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"11.8","Single Cell Type RNA - Langerhans cells [nTPM]":"4.4","Single Cell Type RNA - Late spermatids [nTPM]":"15.2","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"10.9","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"8.5","Single Cell Type RNA - Muller glia cells [nTPM]":"3.0","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.9","Single Cell Type RNA - Paneth cells [nTPM]":"13.1","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"6.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"5.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"31.7","Single Cell Type RNA - T-cells [nTPM]":"2.9","Single Cell Type RNA - Theca cells [nTPM]":"10.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.5","Single Cell Type RNA - Urothelial cells [nTPM]":"1.7"},{"Gene":"SLC2A1","Gene synonym":["CSE","DYT18","DYT9","GLUT","GLUT1","HTLVR"],"Ensembl":"ENSG00000117394","Gene description":"Solute carrier family 2 member 1","Uniprot":["P11166"],"Chromosome":"1","Position":"42925353-42958893","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Cataract","Disease variant","Dystonia","Epilepsy","Hereditary hemolytic anemia","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"98.7","skin 1":"79.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"833.8","Erythroid cells":"520.4","Extravillous trophoblasts":"536.4","Syncytiotrophoblasts":"2482.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"241.0","CACO-2":"219.9","Hep G2":"157.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002759","HPA031345","HPA058494"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2000000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB002759":null,"HPA031345":"AB_2673835","HPA058494":"AB_2683734"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.65e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.09e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.39e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.55e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.05e-4"},"Tissue RNA - adipose tissue [nTPM]":"6.9","Tissue RNA - adrenal gland [nTPM]":"3.6","Tissue RNA - amygdala [nTPM]":"24.1","Tissue RNA - appendix [nTPM]":"2.5","Tissue RNA - basal ganglia [nTPM]":"26.1","Tissue RNA - bone marrow [nTPM]":"41.6","Tissue RNA - breast [nTPM]":"7.8","Tissue RNA - cerebellum [nTPM]":"33.7","Tissue RNA - cerebral cortex [nTPM]":"27.7","Tissue RNA - cervix [nTPM]":"28.6","Tissue RNA - choroid plexus [nTPM]":"43.6","Tissue RNA - colon [nTPM]":"6.1","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"5.1","Tissue RNA - epididymis [nTPM]":"1.4","Tissue RNA - esophagus [nTPM]":"54.1","Tissue RNA - fallopian tube [nTPM]":"8.2","Tissue RNA - gallbladder [nTPM]":"1.7","Tissue RNA - heart muscle [nTPM]":"10.0","Tissue RNA - hippocampal formation [nTPM]":"20.6","Tissue RNA - hypothalamus [nTPM]":"28.5","Tissue RNA - kidney [nTPM]":"14.2","Tissue RNA - liver [nTPM]":"1.7","Tissue RNA - lung [nTPM]":"3.3","Tissue RNA - lymph node [nTPM]":"1.0","Tissue RNA - medulla oblongata [nTPM]":"31.9","Tissue RNA - midbrain [nTPM]":"29.3","Tissue RNA - ovary [nTPM]":"5.5","Tissue RNA - pancreas [nTPM]":"2.1","Tissue RNA - parathyroid gland [nTPM]":"4.5","Tissue RNA - pituitary gland [nTPM]":"4.8","Tissue RNA - placenta [nTPM]":"98.7","Tissue RNA - pons [nTPM]":"34.5","Tissue RNA - prostate [nTPM]":"6.0","Tissue RNA - rectum [nTPM]":"1.0","Tissue RNA - retina [nTPM]":"24.6","Tissue RNA - salivary gland [nTPM]":"17.6","Tissue RNA - seminal vesicle [nTPM]":"5.1","Tissue RNA - skeletal muscle [nTPM]":"2.0","Tissue RNA - skin 1 [nTPM]":"79.8","Tissue RNA - small intestine [nTPM]":"4.6","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"24.7","Tissue RNA - spleen [nTPM]":"7.5","Tissue RNA - stomach 1 [nTPM]":"8.4","Tissue RNA - testis [nTPM]":"2.1","Tissue RNA - thalamus [nTPM]":"41.2","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"3.0","Tissue RNA - tongue [nTPM]":"1.5","Tissue RNA - tonsil [nTPM]":"2.1","Tissue RNA - urinary bladder [nTPM]":"19.3","Tissue RNA - vagina [nTPM]":"54.2","Tissue RNA - white matter [nTPM]":"29.4","Cell RNA - A-431 [nTPM]":"60.5","Cell RNA - A549 [nTPM]":"52.9","Cell RNA - AF22 [nTPM]":"66.3","Cell RNA - AN3-CA [nTPM]":"6.2","Cell RNA - ASC diff [nTPM]":"3.5","Cell RNA - ASC TERT1 [nTPM]":"1.2","Cell RNA - BEWO [nTPM]":"241.0","Cell RNA - BJ [nTPM]":"47.8","Cell RNA - BJ hTERT+ [nTPM]":"36.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"27.8","Cell RNA - CACO-2 [nTPM]":"219.9","Cell RNA - CAPAN-2 [nTPM]":"96.3","Cell RNA - Daudi [nTPM]":"22.2","Cell RNA - EFO-21 [nTPM]":"138.9","Cell RNA - fHDF\/TERT166 [nTPM]":"6.0","Cell RNA - GAMG [nTPM]":"26.5","Cell RNA - HaCaT [nTPM]":"43.6","Cell RNA - HAP1 [nTPM]":"12.5","Cell RNA - HBEC3-KT [nTPM]":"52.3","Cell RNA - HBF TERT88 [nTPM]":"14.8","Cell RNA - HDLM-2 [nTPM]":"16.4","Cell RNA - HEK 293 [nTPM]":"10.3","Cell RNA - HEL [nTPM]":"29.8","Cell RNA - HeLa [nTPM]":"20.9","Cell RNA - Hep G2 [nTPM]":"157.4","Cell RNA - HHSteC [nTPM]":"12.9","Cell RNA - HL-60 [nTPM]":"16.8","Cell RNA - HMC-1 [nTPM]":"8.1","Cell RNA - HSkMC [nTPM]":"3.3","Cell RNA - hTCEpi [nTPM]":"21.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.3","Cell RNA - hTERT-HME1 [nTPM]":"20.5","Cell RNA - hTERT-RPE1 [nTPM]":"96.7","Cell RNA - HUVEC TERT2 [nTPM]":"2.9","Cell RNA - JURKAT [nTPM]":"12.8","Cell RNA - K-562 [nTPM]":"81.2","Cell RNA - Karpas-707 [nTPM]":"1.5","Cell RNA - LHCN-M2 [nTPM]":"11.7","Cell RNA - MCF7 [nTPM]":"46.6","Cell RNA - MOLT-4 [nTPM]":"7.4","Cell RNA - NB-4 [nTPM]":"11.7","Cell RNA - NTERA-2 [nTPM]":"35.1","Cell RNA - OE19 [nTPM]":"22.1","Cell RNA - PC-3 [nTPM]":"17.9","Cell RNA - REH [nTPM]":"8.4","Cell RNA - RH-30 [nTPM]":"20.6","Cell RNA - RPMI-8226 [nTPM]":"23.3","Cell RNA - RPTEC TERT1 [nTPM]":"21.7","Cell RNA - RT4 [nTPM]":"17.9","Cell RNA - SCLC-21H [nTPM]":"27.0","Cell RNA - SH-SY5Y [nTPM]":"23.8","Cell RNA - SiHa [nTPM]":"47.7","Cell RNA - SK-BR-3 [nTPM]":"95.6","Cell RNA - SK-MEL-30 [nTPM]":"11.0","Cell RNA - SuSa [nTPM]":"70.0","Cell RNA - T-47d [nTPM]":"3.8","Cell RNA - THP-1 [nTPM]":"16.9","Cell RNA - TIME [nTPM]":"14.9","Cell RNA - U-138 MG [nTPM]":"25.6","Cell RNA - U-2 OS [nTPM]":"28.6","Cell RNA - U-2197 [nTPM]":"6.1","Cell RNA - U-251 MG [nTPM]":"83.8","Cell RNA - U-266\/70 [nTPM]":"5.3","Cell RNA - U-266\/84 [nTPM]":"6.5","Cell RNA - U-698 [nTPM]":"11.5","Cell RNA - U-87 MG [nTPM]":"57.1","Cell RNA - U-937 [nTPM]":"8.2","Cell RNA - WM-115 [nTPM]":"25.5","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"1.2","Blood RNA - gdT-cell [nTPM]":"10.6","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"8.5","Blood RNA - memory B-cell [nTPM]":"10.9","Blood RNA - memory CD4 T-cell [nTPM]":"5.1","Blood RNA - memory CD8 T-cell [nTPM]":"6.7","Blood RNA - myeloid DC [nTPM]":"3.7","Blood RNA - naive B-cell [nTPM]":"8.3","Blood RNA - naive CD4 T-cell [nTPM]":"3.8","Blood RNA - naive CD8 T-cell [nTPM]":"4.8","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"4.3","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"18.4","Blood RNA - T-reg [nTPM]":"6.2","Blood RNA - total PBMC [nTPM]":"4.0","Brain RNA - amygdala [nTPM]":"24.1","Brain RNA - basal ganglia [nTPM]":"26.1","Brain RNA - cerebellum [nTPM]":"33.7","Brain RNA - cerebral cortex [nTPM]":"27.7","Brain RNA - hippocampal formation [nTPM]":"20.6","Brain RNA - hypothalamus [nTPM]":"28.5","Brain RNA - medulla oblongata [nTPM]":"31.9","Brain RNA - midbrain [nTPM]":"29.3","Brain RNA - pons [nTPM]":"34.5","Brain RNA - spinal cord [nTPM]":"24.7","Brain RNA - thalamus [nTPM]":"41.2","Brain RNA - white matter [nTPM]":"29.4","Single Cell Type RNA - Adipocytes [nTPM]":"3.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.8","Single Cell Type RNA - Astrocytes [nTPM]":"12.7","Single Cell Type RNA - B-cells [nTPM]":"25.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"286.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"48.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"286.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"66.0","Single Cell Type RNA - Bipolar cells [nTPM]":"15.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"41.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"26.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"159.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"66.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"833.8","Single Cell Type RNA - dendritic cells [nTPM]":"33.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"53.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"53.2","Single Cell Type RNA - Early spermatids [nTPM]":"4.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"112.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"46.0","Single Cell Type RNA - Endothelial cells [nTPM]":"100.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.4","Single Cell Type RNA - Erythroid cells [nTPM]":"520.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"536.4","Single Cell Type RNA - Fibroblasts [nTPM]":"25.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"118.9","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"6.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"2.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"84.8","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"22.4","Single Cell Type RNA - Ionocytes [nTPM]":"65.1","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"34.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"7.8","Single Cell Type RNA - Macrophages [nTPM]":"5.0","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"71.2","Single Cell Type RNA - monocytes [nTPM]":"36.0","Single Cell Type RNA - Muller glia cells [nTPM]":"350.1","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"120.3","Single Cell Type RNA - Paneth cells [nTPM]":"51.9","Single Cell Type RNA - Peritubular cells [nTPM]":"14.7","Single Cell Type RNA - Plasma cells [nTPM]":"11.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"31.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"118.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"32.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"2.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"99.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"238.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2482.5","Single Cell Type RNA - T-cells [nTPM]":"20.8","Single Cell Type RNA - Theca cells [nTPM]":"5.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.8","Single Cell Type RNA - Urothelial cells [nTPM]":"105.8"},{"Gene":"SLC2A10","Gene synonym":["GLUT10"],"Ensembl":"ENSG00000197496","Gene description":"Solute carrier family 2 member 10","Uniprot":["O95528"],"Chromosome":"20","Position":"46709649-46736347","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"43.6","Intestinal goblet cells":"56.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"75","RNA blood cell specific nTPM":{"basophil":"20.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"75","RNA blood lineage specific nTPM":{"granulocytes":"20.9"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"45.8","HSkMC":"56.6","OE19":"49.8","SK-MEL-30":"60.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041015","HPA055673"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 27: Mucus-secreting cells - Mucin production","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA041015":"AB_2677252","HPA055673":"AB_2682879"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.0","Tissue RNA - adrenal gland [nTPM]":"5.9","Tissue RNA - amygdala [nTPM]":"4.0","Tissue RNA - appendix [nTPM]":"3.5","Tissue RNA - basal ganglia [nTPM]":"4.1","Tissue RNA - bone marrow [nTPM]":"1.2","Tissue RNA - breast [nTPM]":"15.3","Tissue RNA - cerebellum [nTPM]":"3.4","Tissue RNA - cerebral cortex [nTPM]":"3.9","Tissue RNA - cervix [nTPM]":"19.4","Tissue RNA - choroid plexus [nTPM]":"18.9","Tissue RNA - colon [nTPM]":"12.7","Tissue RNA - duodenum [nTPM]":"5.4","Tissue RNA - endometrium 1 [nTPM]":"7.9","Tissue RNA - epididymis [nTPM]":"8.7","Tissue RNA - esophagus [nTPM]":"5.1","Tissue RNA - fallopian tube [nTPM]":"9.9","Tissue RNA - gallbladder [nTPM]":"10.3","Tissue RNA - heart muscle [nTPM]":"5.2","Tissue RNA - hippocampal formation [nTPM]":"3.8","Tissue RNA - hypothalamus [nTPM]":"3.7","Tissue RNA - kidney [nTPM]":"3.5","Tissue RNA - liver [nTPM]":"41.4","Tissue RNA - lung [nTPM]":"6.9","Tissue RNA - lymph node [nTPM]":"1.7","Tissue RNA - medulla oblongata [nTPM]":"5.2","Tissue RNA - midbrain [nTPM]":"4.7","Tissue RNA - ovary [nTPM]":"9.9","Tissue RNA - pancreas [nTPM]":"17.4","Tissue RNA - parathyroid gland [nTPM]":"19.5","Tissue RNA - pituitary gland [nTPM]":"6.3","Tissue RNA - placenta [nTPM]":"11.6","Tissue RNA - pons [nTPM]":"4.0","Tissue RNA - prostate [nTPM]":"31.3","Tissue RNA - rectum [nTPM]":"16.0","Tissue RNA - retina [nTPM]":"1.6","Tissue RNA - salivary gland [nTPM]":"24.0","Tissue RNA - seminal vesicle [nTPM]":"9.9","Tissue RNA - skeletal muscle [nTPM]":"1.5","Tissue RNA - skin 1 [nTPM]":"3.6","Tissue RNA - small intestine [nTPM]":"5.3","Tissue RNA - smooth muscle [nTPM]":"8.5","Tissue RNA - spinal cord [nTPM]":"3.8","Tissue RNA - spleen [nTPM]":"2.6","Tissue RNA - stomach 1 [nTPM]":"22.8","Tissue RNA - testis [nTPM]":"2.6","Tissue RNA - thalamus [nTPM]":"4.0","Tissue RNA - thymus [nTPM]":"1.6","Tissue RNA - thyroid gland [nTPM]":"19.5","Tissue RNA - tongue [nTPM]":"2.7","Tissue RNA - tonsil [nTPM]":"2.1","Tissue RNA - urinary bladder [nTPM]":"9.3","Tissue RNA - vagina [nTPM]":"8.4","Tissue RNA - white matter [nTPM]":"3.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"11.3","Cell RNA - AN3-CA [nTPM]":"11.7","Cell RNA - ASC diff [nTPM]":"45.8","Cell RNA - ASC TERT1 [nTPM]":"38.9","Cell RNA - BEWO [nTPM]":"34.2","Cell RNA - BJ [nTPM]":"22.2","Cell RNA - BJ hTERT+ [nTPM]":"30.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.0","Cell RNA - CACO-2 [nTPM]":"0.9","Cell RNA - CAPAN-2 [nTPM]":"38.9","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"16.3","Cell RNA - fHDF\/TERT166 [nTPM]":"40.6","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"1.1","Cell RNA - HBF TERT88 [nTPM]":"4.8","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"3.3","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"18.6","Cell RNA - HHSteC [nTPM]":"32.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"56.6","Cell RNA - hTCEpi [nTPM]":"1.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"11.8","Cell RNA - HUVEC TERT2 [nTPM]":"4.2","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"17.5","Cell RNA - MCF7 [nTPM]":"41.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"1.2","Cell RNA - NTERA-2 [nTPM]":"4.3","Cell RNA - OE19 [nTPM]":"49.8","Cell RNA - PC-3 [nTPM]":"2.9","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"1.6","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"10.6","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"1.8","Cell RNA - SiHa [nTPM]":"4.3","Cell RNA - SK-BR-3 [nTPM]":"7.2","Cell RNA - SK-MEL-30 [nTPM]":"60.3","Cell RNA - SuSa [nTPM]":"8.1","Cell RNA - T-47d [nTPM]":"5.4","Cell RNA - THP-1 [nTPM]":"9.2","Cell RNA - TIME [nTPM]":"2.6","Cell RNA - U-138 MG [nTPM]":"21.7","Cell RNA - U-2 OS [nTPM]":"9.1","Cell RNA - U-2197 [nTPM]":"17.2","Cell RNA - U-251 MG [nTPM]":"2.9","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"4.6","Blood RNA - basophil [nTPM]":"20.9","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.0","Brain RNA - basal ganglia [nTPM]":"4.1","Brain RNA - cerebellum [nTPM]":"3.4","Brain RNA - cerebral cortex [nTPM]":"3.9","Brain RNA - hippocampal formation [nTPM]":"3.8","Brain RNA - hypothalamus [nTPM]":"3.7","Brain RNA - medulla oblongata [nTPM]":"5.2","Brain RNA - midbrain [nTPM]":"4.7","Brain RNA - pons [nTPM]":"4.0","Brain RNA - spinal cord [nTPM]":"3.8","Brain RNA - thalamus [nTPM]":"4.0","Brain RNA - white matter [nTPM]":"3.4","Single Cell Type RNA - Adipocytes [nTPM]":"4.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.3","Single Cell Type RNA - Astrocytes [nTPM]":"12.4","Single Cell Type RNA - B-cells [nTPM]":"0.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"15.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.7","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"7.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.8","Single Cell Type RNA - Endothelial cells [nTPM]":"4.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"6.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"16.3","Single Cell Type RNA - Fibroblasts [nTPM]":"16.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.0","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"10.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.6","Single Cell Type RNA - Hepatocytes [nTPM]":"43.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"56.6","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"1.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"26.4","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"5.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.1","Single Cell Type RNA - Paneth cells [nTPM]":"10.3","Single Cell Type RNA - Peritubular cells [nTPM]":"17.3","Single Cell Type RNA - Plasma cells [nTPM]":"2.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"27.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.1","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"3.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.6","Single Cell Type RNA - Urothelial cells [nTPM]":"10.9"},{"Gene":"SLC2A2","Gene synonym":["GLUT2"],"Ensembl":"ENSG00000163581","Gene description":"Solute carrier family 2 member 2","Uniprot":["P11168"],"Chromosome":"3","Position":"170996347-171026743","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"liver":"836.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hepatocytes":"457.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"liver cancer":"105.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"55","RNA cell line specific nTPM":{"CACO-2":"7.7","Hep G2":"27.6"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010444","HPA028997"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB010444":"AB_641068","HPA028997":"AB_2672860"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.63e-5"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.8","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"66.1","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"5.2","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"30.8","Tissue RNA - liver [nTPM]":"836.1","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"2.4","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.8","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"48.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.4","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"2.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"7.7","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"27.6","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.8","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.8","Brain RNA - spinal cord [nTPM]":"0.4","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"2.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"90.1","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"6.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"457.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"10.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"2.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"105.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"63.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.8","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SLC2A4","Gene synonym":["GLUT4"],"Ensembl":"ENSG00000181856","Gene description":"Solute carrier family 2 member 4","Uniprot":["P14672"],"Chromosome":"17","Position":"7281718-7288257","Protein class":["Disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":["Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"98.8","skeletal muscle":"223.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cardiomyocytes":"135.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Hep G2":"2.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016544"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB016544":"AB_629533"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Tissue RNA - adipose tissue [nTPM]":"16.9","Tissue RNA - adrenal gland [nTPM]":"5.2","Tissue RNA - amygdala [nTPM]":"1.4","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"1.7","Tissue RNA - bone marrow [nTPM]":"1.1","Tissue RNA - breast [nTPM]":"11.2","Tissue RNA - cerebellum [nTPM]":"0.9","Tissue RNA - cerebral cortex [nTPM]":"1.5","Tissue RNA - cervix [nTPM]":"9.2","Tissue RNA - choroid plexus [nTPM]":"0.9","Tissue RNA - colon [nTPM]":"53.1","Tissue RNA - duodenum [nTPM]":"0.8","Tissue RNA - endometrium 1 [nTPM]":"9.3","Tissue RNA - epididymis [nTPM]":"1.2","Tissue RNA - esophagus [nTPM]":"5.9","Tissue RNA - fallopian tube [nTPM]":"11.3","Tissue RNA - gallbladder [nTPM]":"0.7","Tissue RNA - heart muscle [nTPM]":"98.8","Tissue RNA - hippocampal formation [nTPM]":"1.3","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"2.6","Tissue RNA - liver [nTPM]":"3.7","Tissue RNA - lung [nTPM]":"2.1","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"1.0","Tissue RNA - midbrain [nTPM]":"1.5","Tissue RNA - ovary [nTPM]":"3.2","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"3.4","Tissue RNA - pituitary gland [nTPM]":"4.4","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"1.2","Tissue RNA - prostate [nTPM]":"9.9","Tissue RNA - rectum [nTPM]":"1.1","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"6.3","Tissue RNA - seminal vesicle [nTPM]":"3.3","Tissue RNA - skeletal muscle [nTPM]":"223.6","Tissue RNA - skin 1 [nTPM]":"4.1","Tissue RNA - small intestine [nTPM]":"9.7","Tissue RNA - smooth muscle [nTPM]":"4.3","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"11.7","Tissue RNA - testis [nTPM]":"3.3","Tissue RNA - thalamus [nTPM]":"1.3","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"4.5","Tissue RNA - tongue [nTPM]":"63.2","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"27.0","Tissue RNA - vagina [nTPM]":"5.6","Tissue RNA - white matter [nTPM]":"1.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"2.8","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.6","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.4","Brain RNA - basal ganglia [nTPM]":"1.7","Brain RNA - cerebellum [nTPM]":"0.9","Brain RNA - cerebral cortex [nTPM]":"1.5","Brain RNA - hippocampal formation [nTPM]":"1.3","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"1.0","Brain RNA - midbrain [nTPM]":"1.5","Brain RNA - pons [nTPM]":"1.2","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"1.3","Brain RNA - white matter [nTPM]":"1.1","Single Cell Type RNA - Adipocytes [nTPM]":"1.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"135.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"16.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"3.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"10.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"4.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"2.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"4.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"6.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"8.6","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.8","Single Cell Type RNA - Spermatocytes [nTPM]":"1.7","Single Cell Type RNA - Spermatogonia [nTPM]":"2.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"SLC2A9","Gene synonym":["Glut9","GLUTX","URATv1"],"Ensembl":"ENSG00000109667","Gene description":"Solute carrier family 2 member 9","Uniprot":["Q9NRM0"],"Chromosome":"4","Position":"9771153-10054936","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"29.3","liver":"21.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"27.4","Proximal tubular cells":"72.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"6.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"36.9","myeloid DC":"30.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"30","RNA blood lineage specific nTPM":{"dendritic cells":"30.5","monocytes":"36.9"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HBEC3-KT":"48.1","Hep G2":"23.6","hTCEpi":"19.9","THP-1":"20.5","U-937":"13.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066229","HPA075669"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA066229":"AB_2685639","HPA075669":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.32e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.6","Tissue RNA - adrenal gland [nTPM]":"2.6","Tissue RNA - amygdala [nTPM]":"1.0","Tissue RNA - appendix [nTPM]":"2.0","Tissue RNA - basal ganglia [nTPM]":"1.2","Tissue RNA - bone marrow [nTPM]":"2.1","Tissue RNA - breast [nTPM]":"4.2","Tissue RNA - cerebellum [nTPM]":"1.3","Tissue RNA - cerebral cortex [nTPM]":"1.2","Tissue RNA - cervix [nTPM]":"2.5","Tissue RNA - choroid plexus [nTPM]":"2.7","Tissue RNA - colon [nTPM]":"1.8","Tissue RNA - duodenum [nTPM]":"10.7","Tissue RNA - endometrium 1 [nTPM]":"1.4","Tissue RNA - epididymis [nTPM]":"2.4","Tissue RNA - esophagus [nTPM]":"5.2","Tissue RNA - fallopian tube [nTPM]":"3.5","Tissue RNA - gallbladder [nTPM]":"2.4","Tissue RNA - heart muscle [nTPM]":"2.3","Tissue RNA - hippocampal formation [nTPM]":"1.1","Tissue RNA - hypothalamus [nTPM]":"1.6","Tissue RNA - kidney [nTPM]":"29.3","Tissue RNA - liver [nTPM]":"21.4","Tissue RNA - lung [nTPM]":"4.2","Tissue RNA - lymph node [nTPM]":"2.0","Tissue RNA - medulla oblongata [nTPM]":"2.3","Tissue RNA - midbrain [nTPM]":"1.5","Tissue RNA - ovary [nTPM]":"1.6","Tissue RNA - pancreas [nTPM]":"1.0","Tissue RNA - parathyroid gland [nTPM]":"2.4","Tissue RNA - pituitary gland [nTPM]":"1.4","Tissue RNA - placenta [nTPM]":"7.6","Tissue RNA - pons [nTPM]":"2.0","Tissue RNA - prostate [nTPM]":"3.5","Tissue RNA - rectum [nTPM]":"1.6","Tissue RNA - retina [nTPM]":"1.2","Tissue RNA - salivary gland [nTPM]":"16.6","Tissue RNA - seminal vesicle [nTPM]":"18.8","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"2.2","Tissue RNA - small intestine [nTPM]":"8.4","Tissue RNA - smooth muscle [nTPM]":"2.0","Tissue RNA - spinal cord [nTPM]":"1.8","Tissue RNA - spleen [nTPM]":"1.8","Tissue RNA - stomach 1 [nTPM]":"1.0","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"2.0","Tissue RNA - thymus [nTPM]":"4.2","Tissue RNA - thyroid gland [nTPM]":"2.7","Tissue RNA - tongue [nTPM]":"0.5","Tissue RNA - tonsil [nTPM]":"1.4","Tissue RNA - urinary bladder [nTPM]":"6.4","Tissue RNA - vagina [nTPM]":"4.0","Tissue RNA - white matter [nTPM]":"3.0","Cell RNA - A-431 [nTPM]":"1.3","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.6","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"2.4","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"3.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.7","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"7.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"48.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"8.2","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"23.6","Cell RNA - HHSteC [nTPM]":"1.6","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"6.3","Cell RNA - HSkMC [nTPM]":"3.4","Cell RNA - hTCEpi [nTPM]":"19.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"4.8","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.8","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"2.4","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.4","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"1.5","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"20.5","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"13.5","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"36.9","Blood RNA - eosinophil [nTPM]":"0.9","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"7.6","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"30.5","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"12.2","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"9.1","Brain RNA - amygdala [nTPM]":"1.0","Brain RNA - basal ganglia [nTPM]":"1.2","Brain RNA - cerebellum [nTPM]":"1.3","Brain RNA - cerebral cortex [nTPM]":"1.2","Brain RNA - hippocampal formation [nTPM]":"1.1","Brain RNA - hypothalamus [nTPM]":"1.6","Brain RNA - medulla oblongata [nTPM]":"2.3","Brain RNA - midbrain [nTPM]":"1.5","Brain RNA - pons [nTPM]":"2.0","Brain RNA - spinal cord [nTPM]":"1.8","Brain RNA - thalamus [nTPM]":"2.0","Brain RNA - white matter [nTPM]":"3.0","Single Cell Type RNA - Adipocytes [nTPM]":"1.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"8.1","Single Cell Type RNA - B-cells [nTPM]":"1.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"27.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"5.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.7","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.5","Single Cell Type RNA - Early spermatids [nTPM]":"5.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.8","Single Cell Type RNA - Fibroblasts [nTPM]":"1.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"5.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.9","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"8.7","Single Cell Type RNA - Langerhans cells [nTPM]":"3.7","Single Cell Type RNA - Late spermatids [nTPM]":"3.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"8.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"4.4","Single Cell Type RNA - Muller glia cells [nTPM]":"1.2","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"72.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.6","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"1.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.5","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"0.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.5","Single Cell Type RNA - Urothelial cells [nTPM]":"7.7"},{"Gene":"SLC30A10","Gene synonym":["DKFZp547M236","ZnT-10","ZNT8","ZRC1"],"Ensembl":"ENSG00000196660","Gene description":"Solute carrier family 30 member 10","Uniprot":["Q6XR72"],"Chromosome":"1","Position":"219685427-219958647","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":["Disease variant","Dystonia","Neurodegeneration","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"23.9","liver":"33.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"20.2","Distal enterocytes":"44.3","Early spermatids":"38.3","Hepatocytes":"21.1","Late spermatids":"36.1","Paneth cells":"14.4","Proximal enterocytes":"13.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"14","RNA cancer specific FPKM":{"liver cancer":"7.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEK 293":"2.0","HEL":"1.5","K-562":"1.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064547"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA064547":"AB_2732715"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.19e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"6.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"6.1","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"4.4","Tissue RNA - cerebral cortex [nTPM]":"7.6","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"7.4","Tissue RNA - colon [nTPM]":"3.8","Tissue RNA - duodenum [nTPM]":"23.9","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"5.9","Tissue RNA - hypothalamus [nTPM]":"5.7","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"33.5","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"5.4","Tissue RNA - midbrain [nTPM]":"5.9","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"5.6","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"5.0","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"8.9","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"4.5","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"6.5","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"4.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"2.0","Cell RNA - HEL [nTPM]":"1.5","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"1.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.9","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"6.0","Brain RNA - basal ganglia [nTPM]":"6.1","Brain RNA - cerebellum [nTPM]":"4.4","Brain RNA - cerebral cortex [nTPM]":"7.6","Brain RNA - hippocampal formation [nTPM]":"5.9","Brain RNA - hypothalamus [nTPM]":"5.7","Brain RNA - medulla oblongata [nTPM]":"5.4","Brain RNA - midbrain [nTPM]":"5.9","Brain RNA - pons [nTPM]":"5.6","Brain RNA - spinal cord [nTPM]":"4.5","Brain RNA - thalamus [nTPM]":"6.5","Brain RNA - white matter [nTPM]":"4.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"20.2","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"38.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"21.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"36.1","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"3.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"14.4","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.8","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"1.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.8","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SLC30A2","Gene synonym":["ZNT2"],"Ensembl":"ENSG00000158014","Gene description":"Solute carrier family 30 member 2","Uniprot":["Q9BRI3"],"Chromosome":"1","Position":"26037252-26046118","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"pancreas":"99.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"31.0","Endometrial ciliated cells":"30.5","Glandular and luminal cells":"93.7","Proximal tubular cells":"36.2","Syncytiotrophoblasts":"85.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"19.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"BEWO":"2.1","RPTEC TERT1":"4.5","WM-115":"3.5"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"olfactory bulb":"1.2"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017979"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA017979":"AB_1857085"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.86e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"1.2","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"1.1","Tissue RNA - cerebellum [nTPM]":"1.9","Tissue RNA - cerebral cortex [nTPM]":"1.0","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"0.5","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"0.5","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"6.7","Tissue RNA - heart muscle [nTPM]":"6.3","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"20.2","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"99.8","Tissue RNA - parathyroid gland [nTPM]":"2.2","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"4.5","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"1.6","Tissue RNA - seminal vesicle [nTPM]":"2.3","Tissue RNA - skeletal muscle [nTPM]":"3.8","Tissue RNA - skin 1 [nTPM]":"1.0","Tissue RNA - small intestine [nTPM]":"0.8","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"19.8","Tissue RNA - tongue [nTPM]":"0.7","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.5","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"2.1","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"4.5","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.7","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"3.5","Blood RNA - basophil [nTPM]":"0.9","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"1.9","Brain RNA - cerebral cortex [nTPM]":"1.0","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"4.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"31.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"30.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.7","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.8","Single Cell Type RNA - Fibroblasts [nTPM]":"0.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"93.7","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.9","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"36.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"85.1","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"SLC30A9","Gene synonym":["C4orf1","GAC63","HUEL","ZNT9"],"Ensembl":"ENSG00000014824","Gene description":"Solute carrier family 30 member 9","Uniprot":["Q6PML9"],"Chromosome":"4","Position":"41990502-42090461","Protein class":["Disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transcription","Transcription regulation","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004014"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA004014":"AB_1080005"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.86e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.8","Tissue RNA - adrenal gland [nTPM]":"15.4","Tissue RNA - amygdala [nTPM]":"11.4","Tissue RNA - appendix [nTPM]":"6.9","Tissue RNA - basal ganglia [nTPM]":"12.4","Tissue RNA - bone marrow [nTPM]":"5.8","Tissue RNA - breast [nTPM]":"13.8","Tissue RNA - cerebellum [nTPM]":"12.0","Tissue RNA - cerebral cortex [nTPM]":"16.1","Tissue RNA - cervix [nTPM]":"11.8","Tissue RNA - choroid plexus [nTPM]":"12.2","Tissue RNA - colon [nTPM]":"13.4","Tissue RNA - duodenum [nTPM]":"12.6","Tissue RNA - endometrium 1 [nTPM]":"10.3","Tissue RNA - epididymis [nTPM]":"16.0","Tissue RNA - esophagus [nTPM]":"9.3","Tissue RNA - fallopian tube [nTPM]":"9.9","Tissue RNA - gallbladder [nTPM]":"8.6","Tissue RNA - heart muscle [nTPM]":"21.1","Tissue RNA - hippocampal formation [nTPM]":"12.8","Tissue RNA - hypothalamus [nTPM]":"11.9","Tissue RNA - kidney [nTPM]":"30.5","Tissue RNA - liver [nTPM]":"14.2","Tissue RNA - lung [nTPM]":"8.9","Tissue RNA - lymph node [nTPM]":"7.4","Tissue RNA - medulla oblongata [nTPM]":"11.1","Tissue RNA - midbrain [nTPM]":"11.3","Tissue RNA - ovary [nTPM]":"11.1","Tissue RNA - pancreas [nTPM]":"12.9","Tissue RNA - parathyroid gland [nTPM]":"22.7","Tissue RNA - pituitary gland [nTPM]":"14.6","Tissue RNA - placenta [nTPM]":"9.4","Tissue RNA - pons [nTPM]":"11.6","Tissue RNA - prostate [nTPM]":"13.6","Tissue RNA - rectum [nTPM]":"13.9","Tissue RNA - retina [nTPM]":"19.8","Tissue RNA - salivary gland [nTPM]":"12.2","Tissue RNA - seminal vesicle [nTPM]":"10.0","Tissue RNA - skeletal muscle [nTPM]":"14.7","Tissue RNA - skin 1 [nTPM]":"9.6","Tissue RNA - small intestine [nTPM]":"11.6","Tissue RNA - smooth muscle [nTPM]":"8.5","Tissue RNA - spinal cord [nTPM]":"10.9","Tissue RNA - spleen [nTPM]":"7.9","Tissue RNA - stomach 1 [nTPM]":"12.9","Tissue RNA - testis [nTPM]":"6.8","Tissue RNA - thalamus [nTPM]":"11.5","Tissue RNA - thymus [nTPM]":"9.1","Tissue RNA - thyroid gland [nTPM]":"17.3","Tissue RNA - tongue [nTPM]":"20.5","Tissue RNA - tonsil [nTPM]":"7.8","Tissue RNA - urinary bladder [nTPM]":"9.5","Tissue RNA - vagina [nTPM]":"8.0","Tissue RNA - white matter [nTPM]":"11.7","Cell RNA - A-431 [nTPM]":"12.7","Cell RNA - A549 [nTPM]":"6.2","Cell RNA - AF22 [nTPM]":"20.3","Cell RNA - AN3-CA [nTPM]":"23.2","Cell RNA - ASC diff [nTPM]":"15.3","Cell RNA - ASC TERT1 [nTPM]":"21.3","Cell RNA - BEWO [nTPM]":"11.4","Cell RNA - BJ [nTPM]":"17.3","Cell RNA - BJ hTERT+ [nTPM]":"20.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.5","Cell RNA - CACO-2 [nTPM]":"6.4","Cell RNA - CAPAN-2 [nTPM]":"16.2","Cell RNA - Daudi [nTPM]":"13.0","Cell RNA - EFO-21 [nTPM]":"12.2","Cell RNA - fHDF\/TERT166 [nTPM]":"20.0","Cell RNA - GAMG [nTPM]":"19.1","Cell RNA - HaCaT [nTPM]":"6.3","Cell RNA - HAP1 [nTPM]":"17.3","Cell RNA - HBEC3-KT [nTPM]":"14.3","Cell RNA - HBF TERT88 [nTPM]":"21.1","Cell RNA - HDLM-2 [nTPM]":"4.4","Cell RNA - HEK 293 [nTPM]":"10.2","Cell RNA - HEL [nTPM]":"14.9","Cell RNA - HeLa [nTPM]":"10.7","Cell RNA - Hep G2 [nTPM]":"10.9","Cell RNA - HHSteC [nTPM]":"27.1","Cell RNA - HL-60 [nTPM]":"20.8","Cell RNA - HMC-1 [nTPM]":"10.3","Cell RNA - HSkMC [nTPM]":"17.0","Cell RNA - hTCEpi [nTPM]":"14.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.7","Cell RNA - hTERT-HME1 [nTPM]":"16.5","Cell RNA - hTERT-RPE1 [nTPM]":"23.8","Cell RNA - HUVEC TERT2 [nTPM]":"16.3","Cell RNA - JURKAT [nTPM]":"12.9","Cell RNA - K-562 [nTPM]":"20.4","Cell RNA - Karpas-707 [nTPM]":"6.0","Cell RNA - LHCN-M2 [nTPM]":"26.2","Cell RNA - MCF7 [nTPM]":"6.1","Cell RNA - MOLT-4 [nTPM]":"12.0","Cell RNA - NB-4 [nTPM]":"19.6","Cell RNA - NTERA-2 [nTPM]":"15.6","Cell RNA - OE19 [nTPM]":"19.7","Cell RNA - PC-3 [nTPM]":"8.5","Cell RNA - REH [nTPM]":"5.9","Cell RNA - RH-30 [nTPM]":"18.4","Cell RNA - RPMI-8226 [nTPM]":"10.8","Cell RNA - RPTEC TERT1 [nTPM]":"30.2","Cell RNA - RT4 [nTPM]":"10.6","Cell RNA - SCLC-21H [nTPM]":"22.5","Cell RNA - SH-SY5Y [nTPM]":"25.3","Cell RNA - SiHa [nTPM]":"12.3","Cell RNA - SK-BR-3 [nTPM]":"13.5","Cell RNA - SK-MEL-30 [nTPM]":"15.9","Cell RNA - SuSa [nTPM]":"14.3","Cell RNA - T-47d [nTPM]":"17.2","Cell RNA - THP-1 [nTPM]":"15.5","Cell RNA - TIME [nTPM]":"17.7","Cell RNA - U-138 MG [nTPM]":"17.4","Cell RNA - U-2 OS [nTPM]":"10.1","Cell RNA - U-2197 [nTPM]":"17.6","Cell RNA - U-251 MG [nTPM]":"20.3","Cell RNA - U-266\/70 [nTPM]":"11.9","Cell RNA - U-266\/84 [nTPM]":"9.5","Cell RNA - U-698 [nTPM]":"12.3","Cell RNA - U-87 MG [nTPM]":"23.8","Cell RNA - U-937 [nTPM]":"17.4","Cell RNA - WM-115 [nTPM]":"15.5","Blood RNA - basophil [nTPM]":"3.1","Blood RNA - classical monocyte [nTPM]":"1.8","Blood RNA - eosinophil [nTPM]":"1.0","Blood RNA - gdT-cell [nTPM]":"1.2","Blood RNA - intermediate monocyte [nTPM]":"2.3","Blood RNA - MAIT T-cell [nTPM]":"1.3","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"1.5","Blood RNA - myeloid DC [nTPM]":"2.5","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.4","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"2.1","Blood RNA - non-classical monocyte [nTPM]":"1.9","Blood RNA - plasmacytoid DC [nTPM]":"1.8","Blood RNA - T-reg [nTPM]":"1.6","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"11.4","Brain RNA - basal ganglia [nTPM]":"12.4","Brain RNA - cerebellum [nTPM]":"12.0","Brain RNA - cerebral cortex [nTPM]":"16.1","Brain RNA - hippocampal formation [nTPM]":"12.8","Brain RNA - hypothalamus [nTPM]":"11.9","Brain RNA - medulla oblongata [nTPM]":"11.1","Brain RNA - midbrain [nTPM]":"11.3","Brain RNA - pons [nTPM]":"11.6","Brain RNA - spinal cord [nTPM]":"10.9","Brain RNA - thalamus [nTPM]":"11.5","Brain RNA - white matter [nTPM]":"11.7","Single Cell Type RNA - Adipocytes [nTPM]":"19.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"44.5","Single Cell Type RNA - Astrocytes [nTPM]":"48.3","Single Cell Type RNA - B-cells [nTPM]":"26.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"24.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"34.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"30.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"90.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"33.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"44.4","Single Cell Type RNA - dendritic cells [nTPM]":"11.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"33.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"103.7","Single Cell Type RNA - Ductal cells [nTPM]":"35.9","Single Cell Type RNA - Early spermatids [nTPM]":"7.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.2","Single Cell Type RNA - Endothelial cells [nTPM]":"22.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"33.5","Single Cell Type RNA - Erythroid cells [nTPM]":"32.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"70.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"36.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"34.0","Single Cell Type RNA - Fibroblasts [nTPM]":"27.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"37.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.8","Single Cell Type RNA - granulocytes [nTPM]":"34.2","Single Cell Type RNA - Granulosa cells [nTPM]":"33.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.4","Single Cell Type RNA - Hepatocytes [nTPM]":"25.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.2","Single Cell Type RNA - Horizontal cells [nTPM]":"50.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"74.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"36.7","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"22.2","Single Cell Type RNA - Langerhans cells [nTPM]":"21.1","Single Cell Type RNA - Late spermatids [nTPM]":"8.7","Single Cell Type RNA - Leydig cells [nTPM]":"20.8","Single Cell Type RNA - Macrophages [nTPM]":"23.8","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"43.1","Single Cell Type RNA - monocytes [nTPM]":"28.0","Single Cell Type RNA - Muller glia cells [nTPM]":"29.7","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"63.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"84.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"34.3","Single Cell Type RNA - Paneth cells [nTPM]":"17.4","Single Cell Type RNA - Peritubular cells [nTPM]":"22.6","Single Cell Type RNA - Plasma cells [nTPM]":"35.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"27.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"25.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"111.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"43.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"39.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"29.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"28.1","Single Cell Type RNA - Spermatocytes [nTPM]":"16.1","Single Cell Type RNA - Spermatogonia [nTPM]":"18.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"40.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"49.4","Single Cell Type RNA - T-cells [nTPM]":"21.2","Single Cell Type RNA - Theca cells [nTPM]":"44.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"38.3","Single Cell Type RNA - Urothelial cells [nTPM]":"24.2"},{"Gene":"SLC33A1","Gene synonym":["ACATN","AT-1","AT1","SPG42"],"Ensembl":"ENSG00000169359","Gene description":"Solute carrier family 33 member 1","Uniprot":["O00400"],"Chromosome":"3","Position":"155821024-155854456","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Cataract","Deafness","Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042430"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA042430":"AB_10806238"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.8","Tissue RNA - adrenal gland [nTPM]":"11.0","Tissue RNA - amygdala [nTPM]":"3.9","Tissue RNA - appendix [nTPM]":"4.9","Tissue RNA - basal ganglia [nTPM]":"4.8","Tissue RNA - bone marrow [nTPM]":"2.9","Tissue RNA - breast [nTPM]":"8.4","Tissue RNA - cerebellum [nTPM]":"4.6","Tissue RNA - cerebral cortex [nTPM]":"4.7","Tissue RNA - cervix [nTPM]":"12.3","Tissue RNA - choroid plexus [nTPM]":"9.2","Tissue RNA - colon [nTPM]":"7.2","Tissue RNA - duodenum [nTPM]":"6.9","Tissue RNA - endometrium 1 [nTPM]":"8.8","Tissue RNA - epididymis [nTPM]":"12.9","Tissue RNA - esophagus [nTPM]":"8.0","Tissue RNA - fallopian tube [nTPM]":"9.5","Tissue RNA - gallbladder [nTPM]":"7.8","Tissue RNA - heart muscle [nTPM]":"7.6","Tissue RNA - hippocampal formation [nTPM]":"4.6","Tissue RNA - hypothalamus [nTPM]":"5.3","Tissue RNA - kidney [nTPM]":"10.4","Tissue RNA - liver [nTPM]":"17.2","Tissue RNA - lung [nTPM]":"8.4","Tissue RNA - lymph node [nTPM]":"5.0","Tissue RNA - medulla oblongata [nTPM]":"4.4","Tissue RNA - midbrain [nTPM]":"4.2","Tissue RNA - ovary [nTPM]":"8.0","Tissue RNA - pancreas [nTPM]":"30.9","Tissue RNA - parathyroid gland [nTPM]":"11.6","Tissue RNA - pituitary gland [nTPM]":"5.9","Tissue RNA - placenta [nTPM]":"6.6","Tissue RNA - pons [nTPM]":"4.6","Tissue RNA - prostate [nTPM]":"8.3","Tissue RNA - rectum [nTPM]":"6.4","Tissue RNA - retina [nTPM]":"6.8","Tissue RNA - salivary gland [nTPM]":"11.2","Tissue RNA - seminal vesicle [nTPM]":"11.0","Tissue RNA - skeletal muscle [nTPM]":"4.7","Tissue RNA - skin 1 [nTPM]":"6.4","Tissue RNA - small intestine [nTPM]":"7.7","Tissue RNA - smooth muscle [nTPM]":"7.1","Tissue RNA - spinal cord [nTPM]":"5.2","Tissue RNA - spleen [nTPM]":"5.8","Tissue RNA - stomach 1 [nTPM]":"8.8","Tissue RNA - testis [nTPM]":"5.4","Tissue RNA - thalamus [nTPM]":"5.2","Tissue RNA - thymus [nTPM]":"7.1","Tissue RNA - thyroid gland [nTPM]":"18.8","Tissue RNA - tongue [nTPM]":"4.8","Tissue RNA - tonsil [nTPM]":"6.2","Tissue RNA - urinary bladder [nTPM]":"6.8","Tissue RNA - vagina [nTPM]":"7.9","Tissue RNA - white matter [nTPM]":"7.3","Cell RNA - A-431 [nTPM]":"18.9","Cell RNA - A549 [nTPM]":"17.7","Cell RNA - AF22 [nTPM]":"7.3","Cell RNA - AN3-CA [nTPM]":"8.3","Cell RNA - ASC diff [nTPM]":"24.4","Cell RNA - ASC TERT1 [nTPM]":"23.5","Cell RNA - BEWO [nTPM]":"12.9","Cell RNA - BJ [nTPM]":"13.1","Cell RNA - BJ hTERT+ [nTPM]":"21.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"18.7","Cell RNA - CACO-2 [nTPM]":"8.5","Cell RNA - CAPAN-2 [nTPM]":"22.0","Cell RNA - Daudi [nTPM]":"9.9","Cell RNA - EFO-21 [nTPM]":"24.1","Cell RNA - fHDF\/TERT166 [nTPM]":"13.1","Cell RNA - GAMG [nTPM]":"19.8","Cell RNA - HaCaT [nTPM]":"17.1","Cell RNA - HAP1 [nTPM]":"14.3","Cell RNA - HBEC3-KT [nTPM]":"15.2","Cell RNA - HBF TERT88 [nTPM]":"20.8","Cell RNA - HDLM-2 [nTPM]":"16.5","Cell RNA - HEK 293 [nTPM]":"13.3","Cell RNA - HEL [nTPM]":"11.3","Cell RNA - HeLa [nTPM]":"6.5","Cell RNA - Hep G2 [nTPM]":"15.8","Cell RNA - HHSteC [nTPM]":"41.5","Cell RNA - HL-60 [nTPM]":"13.3","Cell RNA - HMC-1 [nTPM]":"8.9","Cell RNA - HSkMC [nTPM]":"18.4","Cell RNA - hTCEpi [nTPM]":"26.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.7","Cell RNA - hTERT-HME1 [nTPM]":"49.5","Cell RNA - hTERT-RPE1 [nTPM]":"20.5","Cell RNA - HUVEC TERT2 [nTPM]":"19.8","Cell RNA - JURKAT [nTPM]":"12.4","Cell RNA - K-562 [nTPM]":"8.6","Cell RNA - Karpas-707 [nTPM]":"27.8","Cell RNA - LHCN-M2 [nTPM]":"14.3","Cell RNA - MCF7 [nTPM]":"14.3","Cell RNA - MOLT-4 [nTPM]":"5.0","Cell RNA - NB-4 [nTPM]":"3.7","Cell RNA - NTERA-2 [nTPM]":"6.8","Cell RNA - OE19 [nTPM]":"17.7","Cell RNA - PC-3 [nTPM]":"14.9","Cell RNA - REH [nTPM]":"5.6","Cell RNA - RH-30 [nTPM]":"8.1","Cell RNA - RPMI-8226 [nTPM]":"29.1","Cell RNA - RPTEC TERT1 [nTPM]":"9.7","Cell RNA - RT4 [nTPM]":"11.8","Cell RNA - SCLC-21H [nTPM]":"7.9","Cell RNA - SH-SY5Y [nTPM]":"5.9","Cell RNA - SiHa [nTPM]":"11.1","Cell RNA - SK-BR-3 [nTPM]":"24.5","Cell RNA - SK-MEL-30 [nTPM]":"21.4","Cell RNA - SuSa [nTPM]":"11.3","Cell RNA - T-47d [nTPM]":"8.1","Cell RNA - THP-1 [nTPM]":"11.2","Cell RNA - TIME [nTPM]":"21.4","Cell RNA - U-138 MG [nTPM]":"10.1","Cell RNA - U-2 OS [nTPM]":"4.9","Cell RNA - U-2197 [nTPM]":"17.9","Cell RNA - U-251 MG [nTPM]":"13.1","Cell RNA - U-266\/70 [nTPM]":"33.2","Cell RNA - U-266\/84 [nTPM]":"14.4","Cell RNA - U-698 [nTPM]":"12.3","Cell RNA - U-87 MG [nTPM]":"14.6","Cell RNA - U-937 [nTPM]":"8.8","Cell RNA - WM-115 [nTPM]":"14.0","Blood RNA - basophil [nTPM]":"12.7","Blood RNA - classical monocyte [nTPM]":"8.4","Blood RNA - eosinophil [nTPM]":"6.2","Blood RNA - gdT-cell [nTPM]":"8.9","Blood RNA - intermediate monocyte [nTPM]":"6.3","Blood RNA - MAIT T-cell [nTPM]":"9.6","Blood RNA - memory B-cell [nTPM]":"5.4","Blood RNA - memory CD4 T-cell [nTPM]":"6.0","Blood RNA - memory CD8 T-cell [nTPM]":"6.8","Blood RNA - myeloid DC [nTPM]":"10.4","Blood RNA - naive B-cell [nTPM]":"3.5","Blood RNA - naive CD4 T-cell [nTPM]":"5.4","Blood RNA - naive CD8 T-cell [nTPM]":"5.5","Blood RNA - neutrophil [nTPM]":"1.7","Blood RNA - NK-cell [nTPM]":"6.6","Blood RNA - non-classical monocyte [nTPM]":"6.5","Blood RNA - plasmacytoid DC [nTPM]":"16.1","Blood RNA - T-reg [nTPM]":"5.7","Blood RNA - total PBMC [nTPM]":"5.9","Brain RNA - amygdala [nTPM]":"3.9","Brain RNA - basal ganglia [nTPM]":"4.8","Brain RNA - cerebellum [nTPM]":"4.6","Brain RNA - cerebral cortex [nTPM]":"4.7","Brain RNA - hippocampal formation [nTPM]":"4.6","Brain RNA - hypothalamus [nTPM]":"5.3","Brain RNA - medulla oblongata [nTPM]":"4.4","Brain RNA - midbrain [nTPM]":"4.2","Brain RNA - pons [nTPM]":"4.6","Brain RNA - spinal cord [nTPM]":"5.2","Brain RNA - thalamus [nTPM]":"5.2","Brain RNA - white matter [nTPM]":"7.3","Single Cell Type RNA - Adipocytes [nTPM]":"9.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.0","Single Cell Type RNA - Astrocytes [nTPM]":"16.0","Single Cell Type RNA - B-cells [nTPM]":"14.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"20.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.2","Single Cell Type RNA - Bipolar cells [nTPM]":"17.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"23.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"21.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.2","Single Cell Type RNA - dendritic cells [nTPM]":"21.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"15.3","Single Cell Type RNA - Early spermatids [nTPM]":"13.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.3","Single Cell Type RNA - Endothelial cells [nTPM]":"13.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.5","Single Cell Type RNA - Erythroid cells [nTPM]":"8.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"28.3","Single Cell Type RNA - Fibroblasts [nTPM]":"19.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.6","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"12.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.4","Single Cell Type RNA - Hepatocytes [nTPM]":"64.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.5","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.1","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"14.7","Single Cell Type RNA - Langerhans cells [nTPM]":"15.8","Single Cell Type RNA - Late spermatids [nTPM]":"13.2","Single Cell Type RNA - Leydig cells [nTPM]":"18.6","Single Cell Type RNA - Macrophages [nTPM]":"15.2","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"19.0","Single Cell Type RNA - Muller glia cells [nTPM]":"15.4","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.4","Single Cell Type RNA - Paneth cells [nTPM]":"5.3","Single Cell Type RNA - Peritubular cells [nTPM]":"21.4","Single Cell Type RNA - Plasma cells [nTPM]":"33.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.0","Single Cell Type RNA - Spermatocytes [nTPM]":"19.5","Single Cell Type RNA - Spermatogonia [nTPM]":"9.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"37.6","Single Cell Type RNA - T-cells [nTPM]":"15.3","Single Cell Type RNA - Theca cells [nTPM]":"10.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.9","Single Cell Type RNA - Urothelial cells [nTPM]":"10.9"},{"Gene":"SLC34A1","Gene synonym":["NAPI-3","NPT2","NPTIIa","SLC11","SLC17A2"],"Ensembl":"ENSG00000131183","Gene description":"Solute carrier family 34 member 1","Uniprot":["Q06495"],"Chromosome":"5","Position":"177379235-177398848","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"54","RNA tissue specific nTPM":{"kidney":"155.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"14","RNA single cell type specific nTPM":{"Proximal tubular cells":"143.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"renal cancer":"1.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"12","RNA cell line specific nTPM":{"HEL":"2.4","U-937":"1.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051255","HPA077175"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear speckles","Plasma membrane","Mitotic spindle","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Nuclear speckles","Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Mitotic spindle","Cytosol"],"Antibody RRID":{"HPA051255":"AB_2681409","HPA077175":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"155.4","Tissue RNA - liver [nTPM]":"1.9","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"2.8","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"2.4","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"1.5","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"1.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"143.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"SLC34A2","Gene synonym":["NAPI-3B"],"Ensembl":"ENSG00000157765","Gene description":"Solute carrier family 34 member 2","Uniprot":["O95436"],"Chromosome":"4","Position":"25648011-25678748","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"lung":"753.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"477.5","Alveolar cells type 2":"1315.9","Club cells":"179.9","Glandular and luminal cells":"241.3","Respiratory ciliated cells":"217.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"lung cancer":"252.6","ovarian cancer":"191.7","thyroid cancer":"585.2"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"cerebellum":"2.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"82","RNA cell line specific nTPM":{"BEWO":"32.2","EFO-21":"121.0","RPTEC TERT1":"86.8"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037989","HPA066474"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 19: Lung - Lung function","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 11: Alveolar cells - Smell perception","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA037989":"AB_10670536","HPA066474":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"0.8","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"19.1","Tissue RNA - cerebellum [nTPM]":"2.1","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"66.6","Tissue RNA - choroid plexus [nTPM]":"6.9","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"16.4","Tissue RNA - endometrium 1 [nTPM]":"34.6","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"1.5","Tissue RNA - fallopian tube [nTPM]":"69.8","Tissue RNA - gallbladder [nTPM]":"9.0","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"16.7","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"753.0","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"1.3","Tissue RNA - pancreas [nTPM]":"7.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"4.8","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"1.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"90.2","Tissue RNA - seminal vesicle [nTPM]":"16.8","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"2.6","Tissue RNA - small intestine [nTPM]":"4.3","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.7","Tissue RNA - stomach 1 [nTPM]":"2.5","Tissue RNA - testis [nTPM]":"2.7","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"2.1","Tissue RNA - thyroid gland [nTPM]":"33.6","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"7.4","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"32.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"121.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.7","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"86.8","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"0.9","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"2.1","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"477.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1315.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"79.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"41.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"34.3","Single Cell Type RNA - Club cells [nTPM]":"179.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"72.2","Single Cell Type RNA - Early spermatids [nTPM]":"5.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"78.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"30.3","Single Cell Type RNA - Endothelial cells [nTPM]":"2.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"241.3","Single Cell Type RNA - granulocytes [nTPM]":"29.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.2","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"20.8","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"3.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.8","Single Cell Type RNA - Paneth cells [nTPM]":"2.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"217.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.8","Single Cell Type RNA - Spermatocytes [nTPM]":"2.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"4.8","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.8","Single Cell Type RNA - Urothelial cells [nTPM]":"4.0"},{"Gene":"SLC34A3","Gene synonym":["FLJ38680","NPTIIc"],"Ensembl":"ENSG00000198569","Gene description":"Solute carrier family 34 member 3","Uniprot":["Q8N130"],"Chromosome":"9","Position":"137230757-137236555","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"intestine":"9.7","kidney":"13.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Proximal enterocytes":"83.7","Proximal tubular cells":"40.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"4.0","HDLM-2":"2.8","HeLa":"3.3","MCF7":"7.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023776"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA023776":"AB_1857102"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"2.9","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"13.6","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"1.8","Tissue RNA - midbrain [nTPM]":"2.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.6","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.2","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.5","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"1.6","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"9.7","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"0.8","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"1.1","Cell RNA - A-431 [nTPM]":"0.6","Cell RNA - A549 [nTPM]":"1.2","Cell RNA - AF22 [nTPM]":"0.7","Cell RNA - AN3-CA [nTPM]":"1.5","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.4","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"4.0","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"1.8","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"2.8","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"3.3","Cell RNA - Hep G2 [nTPM]":"1.5","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.6","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"7.6","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.7","Cell RNA - PC-3 [nTPM]":"0.8","Cell RNA - REH [nTPM]":"0.9","Cell RNA - RH-30 [nTPM]":"0.5","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.6","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"1.3","Cell RNA - SiHa [nTPM]":"0.4","Cell RNA - SK-BR-3 [nTPM]":"0.9","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.6","Cell RNA - T-47d [nTPM]":"2.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"1.5","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"0.7","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"1.8","Brain RNA - midbrain [nTPM]":"2.0","Brain RNA - pons [nTPM]":"0.5","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"0.8","Brain RNA - white matter [nTPM]":"1.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"6.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"83.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"40.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SLC35A1","Gene synonym":["CMPST","hCST"],"Ensembl":"ENSG00000164414","Gene description":"Solute carrier family 35 member A1","Uniprot":["P78382"],"Chromosome":"6","Position":"87470623-87512336","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":["Congenital disorder of glycosylation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"103.0","Inhibitory neurons":"87.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 27: Mucus-secreting cells - Mucin production","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.70e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Tissue RNA - adipose tissue [nTPM]":"16.4","Tissue RNA - adrenal gland [nTPM]":"24.0","Tissue RNA - amygdala [nTPM]":"24.6","Tissue RNA - appendix [nTPM]":"15.6","Tissue RNA - basal ganglia [nTPM]":"25.4","Tissue RNA - bone marrow [nTPM]":"11.2","Tissue RNA - breast [nTPM]":"30.9","Tissue RNA - cerebellum [nTPM]":"28.3","Tissue RNA - cerebral cortex [nTPM]":"31.6","Tissue RNA - cervix [nTPM]":"27.8","Tissue RNA - choroid plexus [nTPM]":"28.5","Tissue RNA - colon [nTPM]":"39.6","Tissue RNA - duodenum [nTPM]":"18.8","Tissue RNA - endometrium 1 [nTPM]":"24.9","Tissue RNA - epididymis [nTPM]":"22.1","Tissue RNA - esophagus [nTPM]":"13.9","Tissue RNA - fallopian tube [nTPM]":"20.2","Tissue RNA - gallbladder [nTPM]":"19.5","Tissue RNA - heart muscle [nTPM]":"16.0","Tissue RNA - hippocampal formation [nTPM]":"26.0","Tissue RNA - hypothalamus [nTPM]":"25.5","Tissue RNA - kidney [nTPM]":"21.2","Tissue RNA - liver [nTPM]":"32.9","Tissue RNA - lung [nTPM]":"37.6","Tissue RNA - lymph node [nTPM]":"17.9","Tissue RNA - medulla oblongata [nTPM]":"24.3","Tissue RNA - midbrain [nTPM]":"24.1","Tissue RNA - ovary [nTPM]":"23.1","Tissue RNA - pancreas [nTPM]":"15.8","Tissue RNA - parathyroid gland [nTPM]":"23.7","Tissue RNA - pituitary gland [nTPM]":"18.9","Tissue RNA - placenta [nTPM]":"19.7","Tissue RNA - pons [nTPM]":"24.4","Tissue RNA - prostate [nTPM]":"36.8","Tissue RNA - rectum [nTPM]":"47.6","Tissue RNA - retina [nTPM]":"14.4","Tissue RNA - salivary gland [nTPM]":"31.6","Tissue RNA - seminal vesicle [nTPM]":"16.5","Tissue RNA - skeletal muscle [nTPM]":"13.8","Tissue RNA - skin 1 [nTPM]":"24.9","Tissue RNA - small intestine [nTPM]":"21.5","Tissue RNA - smooth muscle [nTPM]":"22.0","Tissue RNA - spinal cord [nTPM]":"24.5","Tissue RNA - spleen [nTPM]":"19.0","Tissue RNA - stomach 1 [nTPM]":"29.2","Tissue RNA - testis [nTPM]":"13.2","Tissue RNA - thalamus [nTPM]":"24.9","Tissue RNA - thymus [nTPM]":"16.3","Tissue RNA - thyroid gland [nTPM]":"16.9","Tissue RNA - tongue [nTPM]":"15.7","Tissue RNA - tonsil [nTPM]":"16.3","Tissue RNA - urinary bladder [nTPM]":"21.5","Tissue RNA - vagina [nTPM]":"16.7","Tissue RNA - white matter [nTPM]":"25.4","Cell RNA - A-431 [nTPM]":"4.8","Cell RNA - A549 [nTPM]":"11.5","Cell RNA - AF22 [nTPM]":"20.4","Cell RNA - AN3-CA [nTPM]":"24.1","Cell RNA - ASC diff [nTPM]":"54.4","Cell RNA - ASC TERT1 [nTPM]":"49.3","Cell RNA - BEWO [nTPM]":"16.4","Cell RNA - BJ [nTPM]":"13.9","Cell RNA - BJ hTERT+ [nTPM]":"12.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.6","Cell RNA - CACO-2 [nTPM]":"9.9","Cell RNA - CAPAN-2 [nTPM]":"86.0","Cell RNA - Daudi [nTPM]":"17.6","Cell RNA - EFO-21 [nTPM]":"16.8","Cell RNA - fHDF\/TERT166 [nTPM]":"17.3","Cell RNA - GAMG [nTPM]":"31.7","Cell RNA - HaCaT [nTPM]":"18.5","Cell RNA - HAP1 [nTPM]":"24.8","Cell RNA - HBEC3-KT [nTPM]":"11.3","Cell RNA - HBF TERT88 [nTPM]":"14.6","Cell RNA - HDLM-2 [nTPM]":"25.3","Cell RNA - HEK 293 [nTPM]":"18.4","Cell RNA - HEL [nTPM]":"20.0","Cell RNA - HeLa [nTPM]":"14.7","Cell RNA - Hep G2 [nTPM]":"17.8","Cell RNA - HHSteC [nTPM]":"35.7","Cell RNA - HL-60 [nTPM]":"26.3","Cell RNA - HMC-1 [nTPM]":"13.3","Cell RNA - HSkMC [nTPM]":"25.3","Cell RNA - hTCEpi [nTPM]":"26.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.5","Cell RNA - hTERT-HME1 [nTPM]":"26.1","Cell RNA - hTERT-RPE1 [nTPM]":"26.8","Cell RNA - HUVEC TERT2 [nTPM]":"27.5","Cell RNA - JURKAT [nTPM]":"25.5","Cell RNA - K-562 [nTPM]":"26.1","Cell RNA - Karpas-707 [nTPM]":"28.4","Cell RNA - LHCN-M2 [nTPM]":"17.0","Cell RNA - MCF7 [nTPM]":"44.6","Cell RNA - MOLT-4 [nTPM]":"7.3","Cell RNA - NB-4 [nTPM]":"39.6","Cell RNA - NTERA-2 [nTPM]":"11.0","Cell RNA - OE19 [nTPM]":"60.4","Cell RNA - PC-3 [nTPM]":"18.6","Cell RNA - REH [nTPM]":"22.4","Cell RNA - RH-30 [nTPM]":"19.9","Cell RNA - RPMI-8226 [nTPM]":"19.0","Cell RNA - RPTEC TERT1 [nTPM]":"35.6","Cell RNA - RT4 [nTPM]":"20.4","Cell RNA - SCLC-21H [nTPM]":"13.3","Cell RNA - SH-SY5Y [nTPM]":"14.6","Cell RNA - SiHa [nTPM]":"25.7","Cell RNA - SK-BR-3 [nTPM]":"47.4","Cell RNA - SK-MEL-30 [nTPM]":"23.2","Cell RNA - SuSa [nTPM]":"23.3","Cell RNA - T-47d [nTPM]":"42.2","Cell RNA - THP-1 [nTPM]":"53.0","Cell RNA - TIME [nTPM]":"26.0","Cell RNA - U-138 MG [nTPM]":"16.4","Cell RNA - U-2 OS [nTPM]":"11.1","Cell RNA - U-2197 [nTPM]":"18.2","Cell RNA - U-251 MG [nTPM]":"11.3","Cell RNA - U-266\/70 [nTPM]":"21.1","Cell RNA - U-266\/84 [nTPM]":"32.7","Cell RNA - U-698 [nTPM]":"6.5","Cell RNA - U-87 MG [nTPM]":"13.7","Cell RNA - U-937 [nTPM]":"46.2","Cell RNA - WM-115 [nTPM]":"23.7","Blood RNA - basophil [nTPM]":"52.1","Blood RNA - classical monocyte [nTPM]":"54.1","Blood RNA - eosinophil [nTPM]":"22.8","Blood RNA - gdT-cell [nTPM]":"17.5","Blood RNA - intermediate monocyte [nTPM]":"42.8","Blood RNA - MAIT T-cell [nTPM]":"27.1","Blood RNA - memory B-cell [nTPM]":"17.8","Blood RNA - memory CD4 T-cell [nTPM]":"18.7","Blood RNA - memory CD8 T-cell [nTPM]":"21.5","Blood RNA - myeloid DC [nTPM]":"46.9","Blood RNA - naive B-cell [nTPM]":"16.7","Blood RNA - naive CD4 T-cell [nTPM]":"23.7","Blood RNA - naive CD8 T-cell [nTPM]":"22.3","Blood RNA - neutrophil [nTPM]":"13.2","Blood RNA - NK-cell [nTPM]":"17.5","Blood RNA - non-classical monocyte [nTPM]":"44.2","Blood RNA - plasmacytoid DC [nTPM]":"17.3","Blood RNA - T-reg [nTPM]":"26.8","Blood RNA - total PBMC [nTPM]":"36.9","Brain RNA - amygdala [nTPM]":"24.6","Brain RNA - basal ganglia [nTPM]":"25.4","Brain RNA - cerebellum [nTPM]":"28.3","Brain RNA - cerebral cortex [nTPM]":"31.6","Brain RNA - hippocampal formation [nTPM]":"26.0","Brain RNA - hypothalamus [nTPM]":"25.5","Brain RNA - medulla oblongata [nTPM]":"24.3","Brain RNA - midbrain [nTPM]":"24.1","Brain RNA - pons [nTPM]":"24.4","Brain RNA - spinal cord [nTPM]":"24.5","Brain RNA - thalamus [nTPM]":"24.9","Brain RNA - white matter [nTPM]":"25.4","Single Cell Type RNA - Adipocytes [nTPM]":"14.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"33.6","Single Cell Type RNA - Astrocytes [nTPM]":"19.2","Single Cell Type RNA - B-cells [nTPM]":"11.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"37.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Bipolar cells [nTPM]":"6.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"25.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.0","Single Cell Type RNA - dendritic cells [nTPM]":"16.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"27.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"10.1","Single Cell Type RNA - Early spermatids [nTPM]":"10.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.9","Single Cell Type RNA - Endothelial cells [nTPM]":"15.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.0","Single Cell Type RNA - Erythroid cells [nTPM]":"8.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"103.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.7","Single Cell Type RNA - Fibroblasts [nTPM]":"19.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.8","Single Cell Type RNA - granulocytes [nTPM]":"21.6","Single Cell Type RNA - Granulosa cells [nTPM]":"14.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"42.8","Single Cell Type RNA - Hepatocytes [nTPM]":"20.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.6","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"87.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"73.5","Single Cell Type RNA - Ionocytes [nTPM]":"48.8","Single Cell Type RNA - Kupffer cells [nTPM]":"28.2","Single Cell Type RNA - Langerhans cells [nTPM]":"11.1","Single Cell Type RNA - Late spermatids [nTPM]":"7.1","Single Cell Type RNA - Leydig cells [nTPM]":"16.4","Single Cell Type RNA - Macrophages [nTPM]":"15.8","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"24.4","Single Cell Type RNA - monocytes [nTPM]":"27.4","Single Cell Type RNA - Muller glia cells [nTPM]":"17.3","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"42.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"26.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.5","Single Cell Type RNA - Paneth cells [nTPM]":"19.0","Single Cell Type RNA - Peritubular cells [nTPM]":"19.2","Single Cell Type RNA - Plasma cells [nTPM]":"9.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"25.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.0","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.9","Single Cell Type RNA - Spermatocytes [nTPM]":"9.6","Single Cell Type RNA - Spermatogonia [nTPM]":"14.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"27.5","Single Cell Type RNA - T-cells [nTPM]":"14.9","Single Cell Type RNA - Theca cells [nTPM]":"12.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"32.7","Single Cell Type RNA - Urothelial cells [nTPM]":"8.9"},{"Gene":"SLC35A2","Gene synonym":["UGALT","UGAT","UGT","UGT1","UGT2","UGTL"],"Ensembl":"ENSG00000102100","Gene description":"Solute carrier family 35 member A2","Uniprot":["P78381"],"Chromosome":"X","Position":"48903180-48911958","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":["Congenital disorder of glycosylation","Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036087"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 30: Mammary glandular cells - Lactation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA036087":"AB_10604093"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.16e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.64e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.23e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.8","Tissue RNA - adrenal gland [nTPM]":"20.5","Tissue RNA - amygdala [nTPM]":"13.7","Tissue RNA - appendix [nTPM]":"12.7","Tissue RNA - basal ganglia [nTPM]":"14.3","Tissue RNA - bone marrow [nTPM]":"15.9","Tissue RNA - breast [nTPM]":"14.9","Tissue RNA - cerebellum [nTPM]":"14.3","Tissue RNA - cerebral cortex [nTPM]":"14.8","Tissue RNA - cervix [nTPM]":"18.7","Tissue RNA - choroid plexus [nTPM]":"19.4","Tissue RNA - colon [nTPM]":"29.3","Tissue RNA - duodenum [nTPM]":"17.3","Tissue RNA - endometrium 1 [nTPM]":"13.1","Tissue RNA - epididymis [nTPM]":"28.4","Tissue RNA - esophagus [nTPM]":"24.7","Tissue RNA - fallopian tube [nTPM]":"32.6","Tissue RNA - gallbladder [nTPM]":"15.2","Tissue RNA - heart muscle [nTPM]":"15.0","Tissue RNA - hippocampal formation [nTPM]":"14.5","Tissue RNA - hypothalamus [nTPM]":"15.8","Tissue RNA - kidney [nTPM]":"19.8","Tissue RNA - liver [nTPM]":"31.8","Tissue RNA - lung [nTPM]":"18.2","Tissue RNA - lymph node [nTPM]":"11.4","Tissue RNA - medulla oblongata [nTPM]":"14.6","Tissue RNA - midbrain [nTPM]":"15.0","Tissue RNA - ovary [nTPM]":"9.3","Tissue RNA - pancreas [nTPM]":"30.0","Tissue RNA - parathyroid gland [nTPM]":"24.7","Tissue RNA - pituitary gland [nTPM]":"21.3","Tissue RNA - placenta [nTPM]":"19.9","Tissue RNA - pons [nTPM]":"15.4","Tissue RNA - prostate [nTPM]":"17.1","Tissue RNA - rectum [nTPM]":"28.2","Tissue RNA - retina [nTPM]":"3.1","Tissue RNA - salivary gland [nTPM]":"23.8","Tissue RNA - seminal vesicle [nTPM]":"14.8","Tissue RNA - skeletal muscle [nTPM]":"14.0","Tissue RNA - skin 1 [nTPM]":"21.9","Tissue RNA - small intestine [nTPM]":"18.0","Tissue RNA - smooth muscle [nTPM]":"11.7","Tissue RNA - spinal cord [nTPM]":"14.4","Tissue RNA - spleen [nTPM]":"14.7","Tissue RNA - stomach 1 [nTPM]":"25.0","Tissue RNA - testis [nTPM]":"7.1","Tissue RNA - thalamus [nTPM]":"15.9","Tissue RNA - thymus [nTPM]":"11.8","Tissue RNA - thyroid gland [nTPM]":"15.4","Tissue RNA - tongue [nTPM]":"7.2","Tissue RNA - tonsil [nTPM]":"14.7","Tissue RNA - urinary bladder [nTPM]":"19.8","Tissue RNA - vagina [nTPM]":"15.4","Tissue RNA - white matter [nTPM]":"15.9","Cell RNA - A-431 [nTPM]":"48.8","Cell RNA - A549 [nTPM]":"55.2","Cell RNA - AF22 [nTPM]":"18.8","Cell RNA - AN3-CA [nTPM]":"27.3","Cell RNA - ASC diff [nTPM]":"36.5","Cell RNA - ASC TERT1 [nTPM]":"31.6","Cell RNA - BEWO [nTPM]":"29.7","Cell RNA - BJ [nTPM]":"49.7","Cell RNA - BJ hTERT+ [nTPM]":"54.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"51.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"59.9","Cell RNA - CACO-2 [nTPM]":"64.0","Cell RNA - CAPAN-2 [nTPM]":"84.5","Cell RNA - Daudi [nTPM]":"18.8","Cell RNA - EFO-21 [nTPM]":"22.2","Cell RNA - fHDF\/TERT166 [nTPM]":"54.2","Cell RNA - GAMG [nTPM]":"64.4","Cell RNA - HaCaT [nTPM]":"67.0","Cell RNA - HAP1 [nTPM]":"51.7","Cell RNA - HBEC3-KT [nTPM]":"40.0","Cell RNA - HBF TERT88 [nTPM]":"39.7","Cell RNA - HDLM-2 [nTPM]":"27.9","Cell RNA - HEK 293 [nTPM]":"34.0","Cell RNA - HEL [nTPM]":"20.5","Cell RNA - HeLa [nTPM]":"33.1","Cell RNA - Hep G2 [nTPM]":"49.6","Cell RNA - HHSteC [nTPM]":"47.8","Cell RNA - HL-60 [nTPM]":"38.7","Cell RNA - HMC-1 [nTPM]":"40.9","Cell RNA - HSkMC [nTPM]":"35.7","Cell RNA - hTCEpi [nTPM]":"69.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"48.6","Cell RNA - hTERT-HME1 [nTPM]":"39.8","Cell RNA - hTERT-RPE1 [nTPM]":"28.9","Cell RNA - HUVEC TERT2 [nTPM]":"30.6","Cell RNA - JURKAT [nTPM]":"25.9","Cell RNA - K-562 [nTPM]":"38.7","Cell RNA - Karpas-707 [nTPM]":"29.8","Cell RNA - LHCN-M2 [nTPM]":"37.6","Cell RNA - MCF7 [nTPM]":"47.1","Cell RNA - MOLT-4 [nTPM]":"20.5","Cell RNA - NB-4 [nTPM]":"35.0","Cell RNA - NTERA-2 [nTPM]":"39.7","Cell RNA - OE19 [nTPM]":"55.3","Cell RNA - PC-3 [nTPM]":"67.7","Cell RNA - REH [nTPM]":"22.3","Cell RNA - RH-30 [nTPM]":"35.5","Cell RNA - RPMI-8226 [nTPM]":"61.1","Cell RNA - RPTEC TERT1 [nTPM]":"44.4","Cell RNA - RT4 [nTPM]":"39.1","Cell RNA - SCLC-21H [nTPM]":"21.8","Cell RNA - SH-SY5Y [nTPM]":"36.1","Cell RNA - SiHa [nTPM]":"52.9","Cell RNA - SK-BR-3 [nTPM]":"54.5","Cell RNA - SK-MEL-30 [nTPM]":"28.7","Cell RNA - SuSa [nTPM]":"35.1","Cell RNA - T-47d [nTPM]":"80.8","Cell RNA - THP-1 [nTPM]":"30.7","Cell RNA - TIME [nTPM]":"28.2","Cell RNA - U-138 MG [nTPM]":"30.3","Cell RNA - U-2 OS [nTPM]":"30.6","Cell RNA - U-2197 [nTPM]":"55.4","Cell RNA - U-251 MG [nTPM]":"27.5","Cell RNA - U-266\/70 [nTPM]":"45.1","Cell RNA - U-266\/84 [nTPM]":"32.8","Cell RNA - U-698 [nTPM]":"19.6","Cell RNA - U-87 MG [nTPM]":"38.4","Cell RNA - U-937 [nTPM]":"34.1","Cell RNA - WM-115 [nTPM]":"40.3","Blood RNA - basophil [nTPM]":"18.1","Blood RNA - classical monocyte [nTPM]":"22.3","Blood RNA - eosinophil [nTPM]":"40.0","Blood RNA - gdT-cell [nTPM]":"15.3","Blood RNA - intermediate monocyte [nTPM]":"23.4","Blood RNA - MAIT T-cell [nTPM]":"15.8","Blood RNA - memory B-cell [nTPM]":"10.7","Blood RNA - memory CD4 T-cell [nTPM]":"12.6","Blood RNA - memory CD8 T-cell [nTPM]":"13.9","Blood RNA - myeloid DC [nTPM]":"27.7","Blood RNA - naive B-cell [nTPM]":"9.9","Blood RNA - naive CD4 T-cell [nTPM]":"8.3","Blood RNA - naive CD8 T-cell [nTPM]":"14.6","Blood RNA - neutrophil [nTPM]":"24.2","Blood RNA - NK-cell [nTPM]":"13.8","Blood RNA - non-classical monocyte [nTPM]":"17.5","Blood RNA - plasmacytoid DC [nTPM]":"27.7","Blood RNA - T-reg [nTPM]":"13.1","Blood RNA - total PBMC [nTPM]":"11.9","Brain RNA - amygdala [nTPM]":"13.7","Brain RNA - basal ganglia [nTPM]":"14.3","Brain RNA - cerebellum [nTPM]":"14.3","Brain RNA - cerebral cortex [nTPM]":"14.8","Brain RNA - hippocampal formation [nTPM]":"14.5","Brain RNA - hypothalamus [nTPM]":"15.8","Brain RNA - medulla oblongata [nTPM]":"14.6","Brain RNA - midbrain [nTPM]":"15.0","Brain RNA - pons [nTPM]":"15.4","Brain RNA - spinal cord [nTPM]":"14.4","Brain RNA - thalamus [nTPM]":"15.9","Brain RNA - white matter [nTPM]":"15.9","Single Cell Type RNA - Adipocytes [nTPM]":"16.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.0","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"13.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"4.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"23.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"31.0","Single Cell Type RNA - dendritic cells [nTPM]":"15.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"27.4","Single Cell Type RNA - Early spermatids [nTPM]":"3.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"24.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.0","Single Cell Type RNA - Endothelial cells [nTPM]":"13.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.7","Single Cell Type RNA - Erythroid cells [nTPM]":"19.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"32.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"30.6","Single Cell Type RNA - Fibroblasts [nTPM]":"14.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.8","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"8.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"15.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.4","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.5","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"10.1","Single Cell Type RNA - Langerhans cells [nTPM]":"14.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"9.9","Single Cell Type RNA - Macrophages [nTPM]":"12.3","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"21.9","Single Cell Type RNA - Muller glia cells [nTPM]":"9.4","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"27.1","Single Cell Type RNA - Paneth cells [nTPM]":"19.7","Single Cell Type RNA - Peritubular cells [nTPM]":"10.9","Single Cell Type RNA - Plasma cells [nTPM]":"19.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"50.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.4","Single Cell Type RNA - Spermatocytes [nTPM]":"10.3","Single Cell Type RNA - Spermatogonia [nTPM]":"6.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"48.0","Single Cell Type RNA - T-cells [nTPM]":"13.8","Single Cell Type RNA - Theca cells [nTPM]":"12.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"21.7","Single Cell Type RNA - Urothelial cells [nTPM]":"23.4"},{"Gene":"SLC35A3","Gene synonym":[],"Ensembl":"ENSG00000117620","Gene description":"Solute carrier family 35 member A3","Uniprot":["Q9Y2D2"],"Chromosome":"1","Position":"99969351-100035634","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":["Autism spectrum disorder","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"211.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015253"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA015253":"AB_1857106"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.34e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.6","Tissue RNA - adrenal gland [nTPM]":"7.3","Tissue RNA - amygdala [nTPM]":"4.3","Tissue RNA - appendix [nTPM]":"10.4","Tissue RNA - basal ganglia [nTPM]":"5.1","Tissue RNA - bone marrow [nTPM]":"11.4","Tissue RNA - breast [nTPM]":"18.3","Tissue RNA - cerebellum [nTPM]":"6.6","Tissue RNA - cerebral cortex [nTPM]":"5.8","Tissue RNA - cervix [nTPM]":"19.1","Tissue RNA - choroid plexus [nTPM]":"10.0","Tissue RNA - colon [nTPM]":"53.3","Tissue RNA - duodenum [nTPM]":"49.7","Tissue RNA - endometrium 1 [nTPM]":"9.6","Tissue RNA - epididymis [nTPM]":"11.4","Tissue RNA - esophagus [nTPM]":"14.4","Tissue RNA - fallopian tube [nTPM]":"13.1","Tissue RNA - gallbladder [nTPM]":"13.5","Tissue RNA - heart muscle [nTPM]":"5.5","Tissue RNA - hippocampal formation [nTPM]":"4.1","Tissue RNA - hypothalamus [nTPM]":"4.7","Tissue RNA - kidney [nTPM]":"21.3","Tissue RNA - liver [nTPM]":"37.3","Tissue RNA - lung [nTPM]":"11.5","Tissue RNA - lymph node [nTPM]":"8.0","Tissue RNA - medulla oblongata [nTPM]":"4.7","Tissue RNA - midbrain [nTPM]":"4.6","Tissue RNA - ovary [nTPM]":"8.1","Tissue RNA - pancreas [nTPM]":"11.5","Tissue RNA - parathyroid gland [nTPM]":"19.8","Tissue RNA - pituitary gland [nTPM]":"4.8","Tissue RNA - placenta [nTPM]":"10.2","Tissue RNA - pons [nTPM]":"5.1","Tissue RNA - prostate [nTPM]":"23.0","Tissue RNA - rectum [nTPM]":"53.8","Tissue RNA - retina [nTPM]":"6.9","Tissue RNA - salivary gland [nTPM]":"22.0","Tissue RNA - seminal vesicle [nTPM]":"11.6","Tissue RNA - skeletal muscle [nTPM]":"4.9","Tissue RNA - skin 1 [nTPM]":"10.8","Tissue RNA - small intestine [nTPM]":"41.4","Tissue RNA - smooth muscle [nTPM]":"8.8","Tissue RNA - spinal cord [nTPM]":"4.5","Tissue RNA - spleen [nTPM]":"7.9","Tissue RNA - stomach 1 [nTPM]":"33.4","Tissue RNA - testis [nTPM]":"2.8","Tissue RNA - thalamus [nTPM]":"4.9","Tissue RNA - thymus [nTPM]":"18.9","Tissue RNA - thyroid gland [nTPM]":"24.9","Tissue RNA - tongue [nTPM]":"6.1","Tissue RNA - tonsil [nTPM]":"8.9","Tissue RNA - urinary bladder [nTPM]":"10.5","Tissue RNA - vagina [nTPM]":"10.2","Tissue RNA - white matter [nTPM]":"6.3","Cell RNA - A-431 [nTPM]":"28.3","Cell RNA - A549 [nTPM]":"7.6","Cell RNA - AF22 [nTPM]":"6.7","Cell RNA - AN3-CA [nTPM]":"7.1","Cell RNA - ASC diff [nTPM]":"14.8","Cell RNA - ASC TERT1 [nTPM]":"12.9","Cell RNA - BEWO [nTPM]":"26.7","Cell RNA - BJ [nTPM]":"24.5","Cell RNA - BJ hTERT+ [nTPM]":"14.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.6","Cell RNA - CACO-2 [nTPM]":"4.9","Cell RNA - CAPAN-2 [nTPM]":"15.1","Cell RNA - Daudi [nTPM]":"15.1","Cell RNA - EFO-21 [nTPM]":"30.0","Cell RNA - fHDF\/TERT166 [nTPM]":"14.3","Cell RNA - GAMG [nTPM]":"13.3","Cell RNA - HaCaT [nTPM]":"16.0","Cell RNA - HAP1 [nTPM]":"12.7","Cell RNA - HBEC3-KT [nTPM]":"11.0","Cell RNA - HBF TERT88 [nTPM]":"21.6","Cell RNA - HDLM-2 [nTPM]":"18.7","Cell RNA - HEK 293 [nTPM]":"9.4","Cell RNA - HEL [nTPM]":"13.7","Cell RNA - HeLa [nTPM]":"10.7","Cell RNA - Hep G2 [nTPM]":"11.8","Cell RNA - HHSteC [nTPM]":"9.2","Cell RNA - HL-60 [nTPM]":"22.1","Cell RNA - HMC-1 [nTPM]":"1.6","Cell RNA - HSkMC [nTPM]":"6.8","Cell RNA - hTCEpi [nTPM]":"12.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.5","Cell RNA - hTERT-HME1 [nTPM]":"22.2","Cell RNA - hTERT-RPE1 [nTPM]":"11.3","Cell RNA - HUVEC TERT2 [nTPM]":"11.1","Cell RNA - JURKAT [nTPM]":"11.9","Cell RNA - K-562 [nTPM]":"23.0","Cell RNA - Karpas-707 [nTPM]":"21.9","Cell RNA - LHCN-M2 [nTPM]":"19.3","Cell RNA - MCF7 [nTPM]":"7.1","Cell RNA - MOLT-4 [nTPM]":"14.6","Cell RNA - NB-4 [nTPM]":"11.4","Cell RNA - NTERA-2 [nTPM]":"8.2","Cell RNA - OE19 [nTPM]":"16.0","Cell RNA - PC-3 [nTPM]":"24.9","Cell RNA - REH [nTPM]":"4.5","Cell RNA - RH-30 [nTPM]":"20.4","Cell RNA - RPMI-8226 [nTPM]":"9.4","Cell RNA - RPTEC TERT1 [nTPM]":"17.1","Cell RNA - RT4 [nTPM]":"16.0","Cell RNA - SCLC-21H [nTPM]":"8.6","Cell RNA - SH-SY5Y [nTPM]":"4.8","Cell RNA - SiHa [nTPM]":"17.0","Cell RNA - SK-BR-3 [nTPM]":"32.3","Cell RNA - SK-MEL-30 [nTPM]":"13.7","Cell RNA - SuSa [nTPM]":"6.2","Cell RNA - T-47d [nTPM]":"19.7","Cell RNA - THP-1 [nTPM]":"16.6","Cell RNA - TIME [nTPM]":"13.0","Cell RNA - U-138 MG [nTPM]":"14.3","Cell RNA - U-2 OS [nTPM]":"13.0","Cell RNA - U-2197 [nTPM]":"32.0","Cell RNA - U-251 MG [nTPM]":"13.3","Cell RNA - U-266\/70 [nTPM]":"12.9","Cell RNA - U-266\/84 [nTPM]":"16.2","Cell RNA - U-698 [nTPM]":"11.2","Cell RNA - U-87 MG [nTPM]":"23.0","Cell RNA - U-937 [nTPM]":"13.5","Cell RNA - WM-115 [nTPM]":"6.1","Blood RNA - basophil [nTPM]":"4.4","Blood RNA - classical monocyte [nTPM]":"2.1","Blood RNA - eosinophil [nTPM]":"1.1","Blood RNA - gdT-cell [nTPM]":"2.2","Blood RNA - intermediate monocyte [nTPM]":"2.1","Blood RNA - MAIT T-cell [nTPM]":"2.5","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"2.2","Blood RNA - memory CD8 T-cell [nTPM]":"2.6","Blood RNA - myeloid DC [nTPM]":"1.7","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"2.7","Blood RNA - naive CD8 T-cell [nTPM]":"2.3","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"4.3","Blood RNA - non-classical monocyte [nTPM]":"1.7","Blood RNA - plasmacytoid DC [nTPM]":"5.0","Blood RNA - T-reg [nTPM]":"2.8","Blood RNA - total PBMC [nTPM]":"1.9","Brain RNA - amygdala [nTPM]":"4.3","Brain RNA - basal ganglia [nTPM]":"5.1","Brain RNA - cerebellum [nTPM]":"6.6","Brain RNA - cerebral cortex [nTPM]":"5.8","Brain RNA - hippocampal formation [nTPM]":"4.1","Brain RNA - hypothalamus [nTPM]":"4.7","Brain RNA - medulla oblongata [nTPM]":"4.7","Brain RNA - midbrain [nTPM]":"4.6","Brain RNA - pons [nTPM]":"5.1","Brain RNA - spinal cord [nTPM]":"4.5","Brain RNA - thalamus [nTPM]":"4.9","Brain RNA - white matter [nTPM]":"6.3","Single Cell Type RNA - Adipocytes [nTPM]":"23.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"80.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"28.6","Single Cell Type RNA - Astrocytes [nTPM]":"12.4","Single Cell Type RNA - B-cells [nTPM]":"17.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"25.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Bipolar cells [nTPM]":"15.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"33.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"50.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"55.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.4","Single Cell Type RNA - dendritic cells [nTPM]":"51.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"211.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"18.1","Single Cell Type RNA - Early spermatids [nTPM]":"4.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"49.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.4","Single Cell Type RNA - Endothelial cells [nTPM]":"20.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.8","Single Cell Type RNA - Erythroid cells [nTPM]":"9.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"24.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"30.5","Single Cell Type RNA - Fibroblasts [nTPM]":"17.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"43.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"46.3","Single Cell Type RNA - granulocytes [nTPM]":"17.1","Single Cell Type RNA - Granulosa cells [nTPM]":"19.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.7","Single Cell Type RNA - Hepatocytes [nTPM]":"49.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.2","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"26.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"110.6","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"17.8","Single Cell Type RNA - Langerhans cells [nTPM]":"17.1","Single Cell Type RNA - Late spermatids [nTPM]":"2.1","Single Cell Type RNA - Leydig cells [nTPM]":"13.4","Single Cell Type RNA - Macrophages [nTPM]":"14.2","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"18.0","Single Cell Type RNA - Muller glia cells [nTPM]":"19.0","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"30.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"46.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.7","Single Cell Type RNA - Paneth cells [nTPM]":"82.8","Single Cell Type RNA - Peritubular cells [nTPM]":"13.2","Single Cell Type RNA - Plasma cells [nTPM]":"25.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"43.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"112.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"25.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"92.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"25.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.7","Single Cell Type RNA - Spermatocytes [nTPM]":"16.2","Single Cell Type RNA - Spermatogonia [nTPM]":"8.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"29.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.3","Single Cell Type RNA - T-cells [nTPM]":"23.8","Single Cell Type RNA - Theca cells [nTPM]":"12.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"116.4","Single Cell Type RNA - Urothelial cells [nTPM]":"48.4"},{"Gene":"SLC35C1","Gene synonym":["FLJ11320","FUCT1"],"Ensembl":"ENSG00000181830","Gene description":"Solute carrier family 35 member C1","Uniprot":["Q96A29"],"Chromosome":"11","Position":"45804072-45813016","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"84.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"50.6","Distal enterocytes":"54.6","Pancreatic endocrine cells":"50.6","Paneth cells":"54.0","Proximal enterocytes":"58.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064001"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 27: Mucus-secreting cells - Mucin production","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA064001":"AB_2685171"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.68e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.64e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Tissue RNA - adipose tissue [nTPM]":"28.2","Tissue RNA - adrenal gland [nTPM]":"7.3","Tissue RNA - amygdala [nTPM]":"6.6","Tissue RNA - appendix [nTPM]":"10.7","Tissue RNA - basal ganglia [nTPM]":"6.3","Tissue RNA - bone marrow [nTPM]":"2.4","Tissue RNA - breast [nTPM]":"19.8","Tissue RNA - cerebellum [nTPM]":"7.0","Tissue RNA - cerebral cortex [nTPM]":"7.0","Tissue RNA - cervix [nTPM]":"9.6","Tissue RNA - choroid plexus [nTPM]":"6.1","Tissue RNA - colon [nTPM]":"19.8","Tissue RNA - duodenum [nTPM]":"24.4","Tissue RNA - endometrium 1 [nTPM]":"8.8","Tissue RNA - epididymis [nTPM]":"2.3","Tissue RNA - esophagus [nTPM]":"41.5","Tissue RNA - fallopian tube [nTPM]":"7.3","Tissue RNA - gallbladder [nTPM]":"12.2","Tissue RNA - heart muscle [nTPM]":"9.0","Tissue RNA - hippocampal formation [nTPM]":"6.2","Tissue RNA - hypothalamus [nTPM]":"7.2","Tissue RNA - kidney [nTPM]":"7.0","Tissue RNA - liver [nTPM]":"84.5","Tissue RNA - lung [nTPM]":"10.2","Tissue RNA - lymph node [nTPM]":"6.6","Tissue RNA - medulla oblongata [nTPM]":"8.2","Tissue RNA - midbrain [nTPM]":"7.9","Tissue RNA - ovary [nTPM]":"6.3","Tissue RNA - pancreas [nTPM]":"13.4","Tissue RNA - parathyroid gland [nTPM]":"5.6","Tissue RNA - pituitary gland [nTPM]":"10.4","Tissue RNA - placenta [nTPM]":"15.0","Tissue RNA - pons [nTPM]":"7.7","Tissue RNA - prostate [nTPM]":"9.9","Tissue RNA - rectum [nTPM]":"14.3","Tissue RNA - retina [nTPM]":"1.6","Tissue RNA - salivary gland [nTPM]":"26.1","Tissue RNA - seminal vesicle [nTPM]":"5.9","Tissue RNA - skeletal muscle [nTPM]":"6.8","Tissue RNA - skin 1 [nTPM]":"5.1","Tissue RNA - small intestine [nTPM]":"24.1","Tissue RNA - smooth muscle [nTPM]":"9.9","Tissue RNA - spinal cord [nTPM]":"6.5","Tissue RNA - spleen [nTPM]":"8.4","Tissue RNA - stomach 1 [nTPM]":"18.5","Tissue RNA - testis [nTPM]":"5.2","Tissue RNA - thalamus [nTPM]":"8.8","Tissue RNA - thymus [nTPM]":"4.5","Tissue RNA - thyroid gland [nTPM]":"6.6","Tissue RNA - tongue [nTPM]":"6.9","Tissue RNA - tonsil [nTPM]":"10.0","Tissue RNA - urinary bladder [nTPM]":"13.8","Tissue RNA - vagina [nTPM]":"14.9","Tissue RNA - white matter [nTPM]":"6.3","Cell RNA - A-431 [nTPM]":"10.3","Cell RNA - A549 [nTPM]":"25.8","Cell RNA - AF22 [nTPM]":"6.3","Cell RNA - AN3-CA [nTPM]":"16.3","Cell RNA - ASC diff [nTPM]":"19.9","Cell RNA - ASC TERT1 [nTPM]":"19.8","Cell RNA - BEWO [nTPM]":"19.5","Cell RNA - BJ [nTPM]":"22.1","Cell RNA - BJ hTERT+ [nTPM]":"20.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.4","Cell RNA - CACO-2 [nTPM]":"10.7","Cell RNA - CAPAN-2 [nTPM]":"15.2","Cell RNA - Daudi [nTPM]":"10.4","Cell RNA - EFO-21 [nTPM]":"9.9","Cell RNA - fHDF\/TERT166 [nTPM]":"27.3","Cell RNA - GAMG [nTPM]":"19.4","Cell RNA - HaCaT [nTPM]":"26.0","Cell RNA - HAP1 [nTPM]":"13.4","Cell RNA - HBEC3-KT [nTPM]":"13.6","Cell RNA - HBF TERT88 [nTPM]":"6.5","Cell RNA - HDLM-2 [nTPM]":"24.8","Cell RNA - HEK 293 [nTPM]":"14.5","Cell RNA - HEL [nTPM]":"5.9","Cell RNA - HeLa [nTPM]":"20.4","Cell RNA - Hep G2 [nTPM]":"20.6","Cell RNA - HHSteC [nTPM]":"42.6","Cell RNA - HL-60 [nTPM]":"11.4","Cell RNA - HMC-1 [nTPM]":"16.2","Cell RNA - HSkMC [nTPM]":"23.8","Cell RNA - hTCEpi [nTPM]":"16.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.2","Cell RNA - hTERT-HME1 [nTPM]":"11.1","Cell RNA - hTERT-RPE1 [nTPM]":"16.2","Cell RNA - HUVEC TERT2 [nTPM]":"17.6","Cell RNA - JURKAT [nTPM]":"10.3","Cell RNA - K-562 [nTPM]":"13.3","Cell RNA - Karpas-707 [nTPM]":"13.8","Cell RNA - LHCN-M2 [nTPM]":"14.4","Cell RNA - MCF7 [nTPM]":"21.8","Cell RNA - MOLT-4 [nTPM]":"5.9","Cell RNA - NB-4 [nTPM]":"9.0","Cell RNA - NTERA-2 [nTPM]":"27.5","Cell RNA - OE19 [nTPM]":"39.9","Cell RNA - PC-3 [nTPM]":"34.6","Cell RNA - REH [nTPM]":"7.2","Cell RNA - RH-30 [nTPM]":"10.5","Cell RNA - RPMI-8226 [nTPM]":"21.5","Cell RNA - RPTEC TERT1 [nTPM]":"15.1","Cell RNA - RT4 [nTPM]":"25.4","Cell RNA - SCLC-21H [nTPM]":"6.0","Cell RNA - SH-SY5Y [nTPM]":"8.6","Cell RNA - SiHa [nTPM]":"16.6","Cell RNA - SK-BR-3 [nTPM]":"16.3","Cell RNA - SK-MEL-30 [nTPM]":"9.5","Cell RNA - SuSa [nTPM]":"6.6","Cell RNA - T-47d [nTPM]":"13.7","Cell RNA - THP-1 [nTPM]":"6.0","Cell RNA - TIME [nTPM]":"25.7","Cell RNA - U-138 MG [nTPM]":"25.0","Cell RNA - U-2 OS [nTPM]":"14.7","Cell RNA - U-2197 [nTPM]":"46.1","Cell RNA - U-251 MG [nTPM]":"15.6","Cell RNA - U-266\/70 [nTPM]":"9.8","Cell RNA - U-266\/84 [nTPM]":"26.9","Cell RNA - U-698 [nTPM]":"4.9","Cell RNA - U-87 MG [nTPM]":"18.5","Cell RNA - U-937 [nTPM]":"14.4","Cell RNA - WM-115 [nTPM]":"14.2","Blood RNA - basophil [nTPM]":"9.7","Blood RNA - classical monocyte [nTPM]":"11.6","Blood RNA - eosinophil [nTPM]":"12.5","Blood RNA - gdT-cell [nTPM]":"11.0","Blood RNA - intermediate monocyte [nTPM]":"11.9","Blood RNA - MAIT T-cell [nTPM]":"12.3","Blood RNA - memory B-cell [nTPM]":"5.0","Blood RNA - memory CD4 T-cell [nTPM]":"18.0","Blood RNA - memory CD8 T-cell [nTPM]":"14.7","Blood RNA - myeloid DC [nTPM]":"9.6","Blood RNA - naive B-cell [nTPM]":"3.7","Blood RNA - naive CD4 T-cell [nTPM]":"9.3","Blood RNA - naive CD8 T-cell [nTPM]":"8.0","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"5.6","Blood RNA - non-classical monocyte [nTPM]":"8.7","Blood RNA - plasmacytoid DC [nTPM]":"8.2","Blood RNA - T-reg [nTPM]":"13.0","Blood RNA - total PBMC [nTPM]":"10.1","Brain RNA - amygdala [nTPM]":"6.6","Brain RNA - basal ganglia [nTPM]":"6.3","Brain RNA - cerebellum [nTPM]":"7.0","Brain RNA - cerebral cortex [nTPM]":"7.0","Brain RNA - hippocampal formation [nTPM]":"6.2","Brain RNA - hypothalamus [nTPM]":"7.2","Brain RNA - medulla oblongata [nTPM]":"8.2","Brain RNA - midbrain [nTPM]":"7.9","Brain RNA - pons [nTPM]":"7.7","Brain RNA - spinal cord [nTPM]":"6.5","Brain RNA - thalamus [nTPM]":"8.8","Brain RNA - white matter [nTPM]":"6.3","Single Cell Type RNA - Adipocytes [nTPM]":"5.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.2","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"6.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"1.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"50.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"26.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.8","Single Cell Type RNA - dendritic cells [nTPM]":"6.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"54.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"18.4","Single Cell Type RNA - Early spermatids [nTPM]":"4.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.7","Single Cell Type RNA - Endothelial cells [nTPM]":"10.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"3.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"41.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.0","Single Cell Type RNA - Fibroblasts [nTPM]":"10.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.4","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"5.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"42.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.7","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"40.6","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"9.3","Single Cell Type RNA - Langerhans cells [nTPM]":"4.8","Single Cell Type RNA - Late spermatids [nTPM]":"6.0","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"6.3","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"9.5","Single Cell Type RNA - Muller glia cells [nTPM]":"2.8","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"50.6","Single Cell Type RNA - Paneth cells [nTPM]":"54.0","Single Cell Type RNA - Peritubular cells [nTPM]":"5.7","Single Cell Type RNA - Plasma cells [nTPM]":"13.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"58.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.7","Single Cell Type RNA - Spermatocytes [nTPM]":"4.0","Single Cell Type RNA - Spermatogonia [nTPM]":"4.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.3","Single Cell Type RNA - T-cells [nTPM]":"6.5","Single Cell Type RNA - Theca cells [nTPM]":"5.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.4","Single Cell Type RNA - Urothelial cells [nTPM]":"20.1"},{"Gene":"SLC35D1","Gene synonym":["KIAA0260","UGTREL7"],"Ensembl":"ENSG00000116704","Gene description":"Solute carrier family 35 member D1","Uniprot":["Q9NTN3"],"Chromosome":"1","Position":"66999350-67054148","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":["Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"74.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"75.6","Early spermatids":"73.5","Hepatocytes":"114.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"8.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.47e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.55e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Tissue RNA - adipose tissue [nTPM]":"4.9","Tissue RNA - adrenal gland [nTPM]":"6.6","Tissue RNA - amygdala [nTPM]":"4.0","Tissue RNA - appendix [nTPM]":"7.8","Tissue RNA - basal ganglia [nTPM]":"4.6","Tissue RNA - bone marrow [nTPM]":"8.9","Tissue RNA - breast [nTPM]":"5.2","Tissue RNA - cerebellum [nTPM]":"4.1","Tissue RNA - cerebral cortex [nTPM]":"4.2","Tissue RNA - cervix [nTPM]":"7.6","Tissue RNA - choroid plexus [nTPM]":"9.9","Tissue RNA - colon [nTPM]":"26.0","Tissue RNA - duodenum [nTPM]":"15.9","Tissue RNA - endometrium 1 [nTPM]":"5.7","Tissue RNA - epididymis [nTPM]":"4.9","Tissue RNA - esophagus [nTPM]":"5.3","Tissue RNA - fallopian tube [nTPM]":"5.0","Tissue RNA - gallbladder [nTPM]":"6.4","Tissue RNA - heart muscle [nTPM]":"3.7","Tissue RNA - hippocampal formation [nTPM]":"3.8","Tissue RNA - hypothalamus [nTPM]":"4.2","Tissue RNA - kidney [nTPM]":"12.5","Tissue RNA - liver [nTPM]":"74.7","Tissue RNA - lung [nTPM]":"3.7","Tissue RNA - lymph node [nTPM]":"7.5","Tissue RNA - medulla oblongata [nTPM]":"4.7","Tissue RNA - midbrain [nTPM]":"6.1","Tissue RNA - ovary [nTPM]":"7.8","Tissue RNA - pancreas [nTPM]":"7.5","Tissue RNA - parathyroid gland [nTPM]":"8.1","Tissue RNA - pituitary gland [nTPM]":"5.6","Tissue RNA - placenta [nTPM]":"9.5","Tissue RNA - pons [nTPM]":"4.8","Tissue RNA - prostate [nTPM]":"7.2","Tissue RNA - rectum [nTPM]":"26.8","Tissue RNA - retina [nTPM]":"12.3","Tissue RNA - salivary gland [nTPM]":"4.4","Tissue RNA - seminal vesicle [nTPM]":"5.7","Tissue RNA - skeletal muscle [nTPM]":"7.5","Tissue RNA - skin 1 [nTPM]":"9.8","Tissue RNA - small intestine [nTPM]":"16.3","Tissue RNA - smooth muscle [nTPM]":"6.9","Tissue RNA - spinal cord [nTPM]":"4.0","Tissue RNA - spleen [nTPM]":"4.2","Tissue RNA - stomach 1 [nTPM]":"12.9","Tissue RNA - testis [nTPM]":"6.2","Tissue RNA - thalamus [nTPM]":"5.8","Tissue RNA - thymus [nTPM]":"10.1","Tissue RNA - thyroid gland [nTPM]":"6.4","Tissue RNA - tongue [nTPM]":"5.0","Tissue RNA - tonsil [nTPM]":"8.6","Tissue RNA - urinary bladder [nTPM]":"7.3","Tissue RNA - vagina [nTPM]":"6.8","Tissue RNA - white matter [nTPM]":"7.0","Cell RNA - A-431 [nTPM]":"8.3","Cell RNA - A549 [nTPM]":"4.7","Cell RNA - AF22 [nTPM]":"14.2","Cell RNA - AN3-CA [nTPM]":"12.0","Cell RNA - ASC diff [nTPM]":"14.4","Cell RNA - ASC TERT1 [nTPM]":"16.6","Cell RNA - BEWO [nTPM]":"16.8","Cell RNA - BJ [nTPM]":"18.4","Cell RNA - BJ hTERT+ [nTPM]":"24.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.1","Cell RNA - CACO-2 [nTPM]":"10.2","Cell RNA - CAPAN-2 [nTPM]":"2.0","Cell RNA - Daudi [nTPM]":"25.7","Cell RNA - EFO-21 [nTPM]":"7.9","Cell RNA - fHDF\/TERT166 [nTPM]":"14.6","Cell RNA - GAMG [nTPM]":"15.4","Cell RNA - HaCaT [nTPM]":"12.5","Cell RNA - HAP1 [nTPM]":"9.9","Cell RNA - HBEC3-KT [nTPM]":"11.6","Cell RNA - HBF TERT88 [nTPM]":"16.4","Cell RNA - HDLM-2 [nTPM]":"25.8","Cell RNA - HEK 293 [nTPM]":"4.6","Cell RNA - HEL [nTPM]":"19.2","Cell RNA - HeLa [nTPM]":"9.8","Cell RNA - Hep G2 [nTPM]":"20.2","Cell RNA - HHSteC [nTPM]":"12.1","Cell RNA - HL-60 [nTPM]":"22.0","Cell RNA - HMC-1 [nTPM]":"12.2","Cell RNA - HSkMC [nTPM]":"16.3","Cell RNA - hTCEpi [nTPM]":"25.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.4","Cell RNA - hTERT-HME1 [nTPM]":"10.9","Cell RNA - hTERT-RPE1 [nTPM]":"21.0","Cell RNA - HUVEC TERT2 [nTPM]":"5.1","Cell RNA - JURKAT [nTPM]":"10.6","Cell RNA - K-562 [nTPM]":"11.8","Cell RNA - Karpas-707 [nTPM]":"13.3","Cell RNA - LHCN-M2 [nTPM]":"32.0","Cell RNA - MCF7 [nTPM]":"2.8","Cell RNA - MOLT-4 [nTPM]":"13.6","Cell RNA - NB-4 [nTPM]":"6.8","Cell RNA - NTERA-2 [nTPM]":"5.9","Cell RNA - OE19 [nTPM]":"22.5","Cell RNA - PC-3 [nTPM]":"6.4","Cell RNA - REH [nTPM]":"10.4","Cell RNA - RH-30 [nTPM]":"29.3","Cell RNA - RPMI-8226 [nTPM]":"2.9","Cell RNA - RPTEC TERT1 [nTPM]":"6.0","Cell RNA - RT4 [nTPM]":"15.6","Cell RNA - SCLC-21H [nTPM]":"1.7","Cell RNA - SH-SY5Y [nTPM]":"6.3","Cell RNA - SiHa [nTPM]":"27.8","Cell RNA - SK-BR-3 [nTPM]":"8.5","Cell RNA - SK-MEL-30 [nTPM]":"11.9","Cell RNA - SuSa [nTPM]":"7.9","Cell RNA - T-47d [nTPM]":"7.0","Cell RNA - THP-1 [nTPM]":"16.2","Cell RNA - TIME [nTPM]":"5.6","Cell RNA - U-138 MG [nTPM]":"24.2","Cell RNA - U-2 OS [nTPM]":"5.7","Cell RNA - U-2197 [nTPM]":"15.0","Cell RNA - U-251 MG [nTPM]":"17.9","Cell RNA - U-266\/70 [nTPM]":"27.6","Cell RNA - U-266\/84 [nTPM]":"15.4","Cell RNA - U-698 [nTPM]":"14.1","Cell RNA - U-87 MG [nTPM]":"17.2","Cell RNA - U-937 [nTPM]":"3.3","Cell RNA - WM-115 [nTPM]":"10.4","Blood RNA - basophil [nTPM]":"8.5","Blood RNA - classical monocyte [nTPM]":"0.9","Blood RNA - eosinophil [nTPM]":"2.6","Blood RNA - gdT-cell [nTPM]":"2.0","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"2.4","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"1.6","Blood RNA - myeloid DC [nTPM]":"1.1","Blood RNA - naive B-cell [nTPM]":"0.9","Blood RNA - naive CD4 T-cell [nTPM]":"2.1","Blood RNA - naive CD8 T-cell [nTPM]":"2.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"3.5","Blood RNA - non-classical monocyte [nTPM]":"1.7","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"2.8","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"4.0","Brain RNA - basal ganglia [nTPM]":"4.6","Brain RNA - cerebellum [nTPM]":"4.1","Brain RNA - cerebral cortex [nTPM]":"4.2","Brain RNA - hippocampal formation [nTPM]":"3.8","Brain RNA - hypothalamus [nTPM]":"4.2","Brain RNA - medulla oblongata [nTPM]":"4.7","Brain RNA - midbrain [nTPM]":"6.1","Brain RNA - pons [nTPM]":"4.8","Brain RNA - spinal cord [nTPM]":"4.0","Brain RNA - thalamus [nTPM]":"5.8","Brain RNA - white matter [nTPM]":"7.0","Single Cell Type RNA - Adipocytes [nTPM]":"4.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.2","Single Cell Type RNA - Astrocytes [nTPM]":"34.6","Single Cell Type RNA - B-cells [nTPM]":"12.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Bipolar cells [nTPM]":"6.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"4.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"40.5","Single Cell Type RNA - dendritic cells [nTPM]":"18.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"75.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.1","Single Cell Type RNA - Early spermatids [nTPM]":"73.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.9","Single Cell Type RNA - Endothelial cells [nTPM]":"4.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.0","Single Cell Type RNA - Erythroid cells [nTPM]":"9.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.7","Single Cell Type RNA - Fibroblasts [nTPM]":"8.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.7","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"13.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"114.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.9","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"28.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.9","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"8.8","Single Cell Type RNA - Langerhans cells [nTPM]":"4.6","Single Cell Type RNA - Late spermatids [nTPM]":"13.7","Single Cell Type RNA - Leydig cells [nTPM]":"6.2","Single Cell Type RNA - Macrophages [nTPM]":"5.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"3.1","Single Cell Type RNA - Muller glia cells [nTPM]":"17.8","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"37.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"51.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.3","Single Cell Type RNA - Paneth cells [nTPM]":"20.8","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"9.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.5","Single Cell Type RNA - Spermatocytes [nTPM]":"7.7","Single Cell Type RNA - Spermatogonia [nTPM]":"6.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.3","Single Cell Type RNA - T-cells [nTPM]":"12.8","Single Cell Type RNA - Theca cells [nTPM]":"11.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"21.7","Single Cell Type RNA - Urothelial cells [nTPM]":"8.8"},{"Gene":"SLC36A2","Gene synonym":["PAT2","TRAMD1","tramdorin"],"Ensembl":"ENSG00000186335","Gene description":"Solute carrier family 36 member 2","Uniprot":["Q495M3"],"Chromosome":"5","Position":"151314972-151347590","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"60","RNA tissue specific nTPM":{"kidney":"67.6","skeletal muscle":"80.2","tongue":"29.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Proximal tubular cells":"53.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"renal cancer":"0.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044002","HPA062229"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044002":"AB_10964214","HPA062229":"AB_2684717"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.8","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"0.8","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"67.6","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"0.9","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"80.2","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"29.8","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"1.1","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.8","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"6.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"5.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"53.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"SLC38A8","Gene synonym":[],"Ensembl":"ENSG00000166558","Gene description":"Solute carrier family 38 member 8","Uniprot":["A6NNN8"],"Chromosome":"16","Position":"84009667-84042795","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Ion transport","Sodium transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"3.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"16.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"14","RNA cancer specific FPKM":{"melanoma":"6.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SCLC-21H":"2.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"3.7","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"3.9","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"1.3","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.7","Tissue RNA - hippocampal formation [nTPM]":"1.0","Tissue RNA - hypothalamus [nTPM]":"0.8","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"1.1","Tissue RNA - midbrain [nTPM]":"1.6","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.7","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"3.0","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"1.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.8","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"2.5","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.7","Brain RNA - basal ganglia [nTPM]":"3.9","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"1.3","Brain RNA - hippocampal formation [nTPM]":"1.0","Brain RNA - hypothalamus [nTPM]":"0.8","Brain RNA - medulla oblongata [nTPM]":"1.1","Brain RNA - midbrain [nTPM]":"1.6","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"3.0","Brain RNA - white matter [nTPM]":"1.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"16.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"1.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SLC39A13","Gene synonym":["FLJ25785"],"Ensembl":"ENSG00000165915","Gene description":"Solute carrier family 39 member 13","Uniprot":["Q96H72"],"Chromosome":"11","Position":"47407132-47416496","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":["Ehlers-Danlos syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Early spermatids":"298.2","Late spermatids":"905.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043971"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043971":"AB_10959744"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.60e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.73e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.96e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-1"},"Tissue RNA - adipose tissue [nTPM]":"40.9","Tissue RNA - adrenal gland [nTPM]":"42.4","Tissue RNA - amygdala [nTPM]":"28.3","Tissue RNA - appendix [nTPM]":"24.2","Tissue RNA - basal ganglia [nTPM]":"31.4","Tissue RNA - bone marrow [nTPM]":"8.3","Tissue RNA - breast [nTPM]":"37.5","Tissue RNA - cerebellum [nTPM]":"30.6","Tissue RNA - cerebral cortex [nTPM]":"36.3","Tissue RNA - cervix [nTPM]":"51.1","Tissue RNA - choroid plexus [nTPM]":"30.4","Tissue RNA - colon [nTPM]":"53.4","Tissue RNA - duodenum [nTPM]":"14.0","Tissue RNA - endometrium 1 [nTPM]":"77.9","Tissue RNA - epididymis [nTPM]":"8.8","Tissue RNA - esophagus [nTPM]":"21.8","Tissue RNA - fallopian tube [nTPM]":"48.1","Tissue RNA - gallbladder [nTPM]":"20.2","Tissue RNA - heart muscle [nTPM]":"59.5","Tissue RNA - hippocampal formation [nTPM]":"26.0","Tissue RNA - hypothalamus [nTPM]":"27.3","Tissue RNA - kidney [nTPM]":"80.4","Tissue RNA - liver [nTPM]":"26.7","Tissue RNA - lung [nTPM]":"61.4","Tissue RNA - lymph node [nTPM]":"18.2","Tissue RNA - medulla oblongata [nTPM]":"33.0","Tissue RNA - midbrain [nTPM]":"29.7","Tissue RNA - ovary [nTPM]":"50.9","Tissue RNA - pancreas [nTPM]":"42.3","Tissue RNA - parathyroid gland [nTPM]":"27.2","Tissue RNA - pituitary gland [nTPM]":"51.3","Tissue RNA - placenta [nTPM]":"40.6","Tissue RNA - pons [nTPM]":"30.4","Tissue RNA - prostate [nTPM]":"52.7","Tissue RNA - rectum [nTPM]":"6.8","Tissue RNA - retina [nTPM]":"11.0","Tissue RNA - salivary gland [nTPM]":"31.3","Tissue RNA - seminal vesicle [nTPM]":"26.2","Tissue RNA - skeletal muscle [nTPM]":"31.4","Tissue RNA - skin 1 [nTPM]":"32.4","Tissue RNA - small intestine [nTPM]":"31.8","Tissue RNA - smooth muscle [nTPM]":"26.6","Tissue RNA - spinal cord [nTPM]":"26.8","Tissue RNA - spleen [nTPM]":"36.5","Tissue RNA - stomach 1 [nTPM]":"41.2","Tissue RNA - testis [nTPM]":"73.4","Tissue RNA - thalamus [nTPM]":"35.0","Tissue RNA - thymus [nTPM]":"12.3","Tissue RNA - thyroid gland [nTPM]":"46.8","Tissue RNA - tongue [nTPM]":"12.6","Tissue RNA - tonsil [nTPM]":"8.7","Tissue RNA - urinary bladder [nTPM]":"45.6","Tissue RNA - vagina [nTPM]":"37.4","Tissue RNA - white matter [nTPM]":"28.5","Cell RNA - A-431 [nTPM]":"23.3","Cell RNA - A549 [nTPM]":"20.4","Cell RNA - AF22 [nTPM]":"23.5","Cell RNA - AN3-CA [nTPM]":"26.7","Cell RNA - ASC diff [nTPM]":"56.3","Cell RNA - ASC TERT1 [nTPM]":"78.2","Cell RNA - BEWO [nTPM]":"6.8","Cell RNA - BJ [nTPM]":"89.7","Cell RNA - BJ hTERT+ [nTPM]":"66.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"50.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"57.0","Cell RNA - CACO-2 [nTPM]":"8.1","Cell RNA - CAPAN-2 [nTPM]":"15.7","Cell RNA - Daudi [nTPM]":"8.8","Cell RNA - EFO-21 [nTPM]":"22.9","Cell RNA - fHDF\/TERT166 [nTPM]":"69.6","Cell RNA - GAMG [nTPM]":"49.6","Cell RNA - HaCaT [nTPM]":"38.3","Cell RNA - HAP1 [nTPM]":"7.1","Cell RNA - HBEC3-KT [nTPM]":"61.7","Cell RNA - HBF TERT88 [nTPM]":"13.9","Cell RNA - HDLM-2 [nTPM]":"25.7","Cell RNA - HEK 293 [nTPM]":"25.9","Cell RNA - HEL [nTPM]":"4.7","Cell RNA - HeLa [nTPM]":"52.7","Cell RNA - Hep G2 [nTPM]":"16.7","Cell RNA - HHSteC [nTPM]":"84.3","Cell RNA - HL-60 [nTPM]":"8.1","Cell RNA - HMC-1 [nTPM]":"11.0","Cell RNA - HSkMC [nTPM]":"65.4","Cell RNA - hTCEpi [nTPM]":"43.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"31.9","Cell RNA - hTERT-HME1 [nTPM]":"26.1","Cell RNA - hTERT-RPE1 [nTPM]":"62.9","Cell RNA - HUVEC TERT2 [nTPM]":"53.4","Cell RNA - JURKAT [nTPM]":"16.9","Cell RNA - K-562 [nTPM]":"4.5","Cell RNA - Karpas-707 [nTPM]":"19.6","Cell RNA - LHCN-M2 [nTPM]":"54.8","Cell RNA - MCF7 [nTPM]":"20.7","Cell RNA - MOLT-4 [nTPM]":"17.4","Cell RNA - NB-4 [nTPM]":"11.5","Cell RNA - NTERA-2 [nTPM]":"11.0","Cell RNA - OE19 [nTPM]":"19.8","Cell RNA - PC-3 [nTPM]":"28.2","Cell RNA - REH [nTPM]":"20.6","Cell RNA - RH-30 [nTPM]":"33.6","Cell RNA - RPMI-8226 [nTPM]":"8.9","Cell RNA - RPTEC TERT1 [nTPM]":"86.1","Cell RNA - RT4 [nTPM]":"11.1","Cell RNA - SCLC-21H [nTPM]":"19.9","Cell RNA - SH-SY5Y [nTPM]":"37.0","Cell RNA - SiHa [nTPM]":"26.9","Cell RNA - SK-BR-3 [nTPM]":"49.1","Cell RNA - SK-MEL-30 [nTPM]":"26.2","Cell RNA - SuSa [nTPM]":"8.7","Cell RNA - T-47d [nTPM]":"32.8","Cell RNA - THP-1 [nTPM]":"11.7","Cell RNA - TIME [nTPM]":"76.0","Cell RNA - U-138 MG [nTPM]":"76.6","Cell RNA - U-2 OS [nTPM]":"34.6","Cell RNA - U-2197 [nTPM]":"88.1","Cell RNA - U-251 MG [nTPM]":"42.7","Cell RNA - U-266\/70 [nTPM]":"14.9","Cell RNA - U-266\/84 [nTPM]":"5.2","Cell RNA - U-698 [nTPM]":"4.1","Cell RNA - U-87 MG [nTPM]":"85.2","Cell RNA - U-937 [nTPM]":"11.2","Cell RNA - WM-115 [nTPM]":"57.3","Blood RNA - basophil [nTPM]":"2.1","Blood RNA - classical monocyte [nTPM]":"3.6","Blood RNA - eosinophil [nTPM]":"3.2","Blood RNA - gdT-cell [nTPM]":"12.4","Blood RNA - intermediate monocyte [nTPM]":"13.3","Blood RNA - MAIT T-cell [nTPM]":"8.5","Blood RNA - memory B-cell [nTPM]":"4.1","Blood RNA - memory CD4 T-cell [nTPM]":"8.2","Blood RNA - memory CD8 T-cell [nTPM]":"8.9","Blood RNA - myeloid DC [nTPM]":"4.6","Blood RNA - naive B-cell [nTPM]":"5.1","Blood RNA - naive CD4 T-cell [nTPM]":"7.5","Blood RNA - naive CD8 T-cell [nTPM]":"6.4","Blood RNA - neutrophil [nTPM]":"6.6","Blood RNA - NK-cell [nTPM]":"7.4","Blood RNA - non-classical monocyte [nTPM]":"15.3","Blood RNA - plasmacytoid DC [nTPM]":"4.9","Blood RNA - T-reg [nTPM]":"4.5","Blood RNA - total PBMC [nTPM]":"5.9","Brain RNA - amygdala [nTPM]":"28.3","Brain RNA - basal ganglia [nTPM]":"31.4","Brain RNA - cerebellum [nTPM]":"30.6","Brain RNA - cerebral cortex [nTPM]":"36.3","Brain RNA - hippocampal formation [nTPM]":"26.0","Brain RNA - hypothalamus [nTPM]":"27.3","Brain RNA - medulla oblongata [nTPM]":"33.0","Brain RNA - midbrain [nTPM]":"29.7","Brain RNA - pons [nTPM]":"30.4","Brain RNA - spinal cord [nTPM]":"26.8","Brain RNA - thalamus [nTPM]":"35.0","Brain RNA - white matter [nTPM]":"28.5","Single Cell Type RNA - Adipocytes [nTPM]":"20.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.4","Single Cell Type RNA - Astrocytes [nTPM]":"18.6","Single Cell Type RNA - B-cells [nTPM]":"6.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"23.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Bipolar cells [nTPM]":"24.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"8.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.1","Single Cell Type RNA - dendritic cells [nTPM]":"11.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"32.9","Single Cell Type RNA - Early spermatids [nTPM]":"298.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.3","Single Cell Type RNA - Endothelial cells [nTPM]":"20.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"4.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"20.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"16.4","Single Cell Type RNA - Fibroblasts [nTPM]":"37.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.1","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"15.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.8","Single Cell Type RNA - Hepatocytes [nTPM]":"6.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.9","Single Cell Type RNA - Horizontal cells [nTPM]":"32.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.9","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.3","Single Cell Type RNA - Langerhans cells [nTPM]":"12.2","Single Cell Type RNA - Late spermatids [nTPM]":"905.5","Single Cell Type RNA - Leydig cells [nTPM]":"32.9","Single Cell Type RNA - Macrophages [nTPM]":"9.3","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"26.6","Single Cell Type RNA - Muller glia cells [nTPM]":"16.7","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"35.5","Single Cell Type RNA - Paneth cells [nTPM]":"8.3","Single Cell Type RNA - Peritubular cells [nTPM]":"40.3","Single Cell Type RNA - Plasma cells [nTPM]":"8.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.0","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"36.2","Single Cell Type RNA - Spermatocytes [nTPM]":"12.7","Single Cell Type RNA - Spermatogonia [nTPM]":"6.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"19.6","Single Cell Type RNA - T-cells [nTPM]":"9.6","Single Cell Type RNA - Theca cells [nTPM]":"36.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.7","Single Cell Type RNA - Urothelial cells [nTPM]":"8.3"},{"Gene":"SLC39A14","Gene synonym":["KIAA0062","NET34","ZIP14"],"Ensembl":"ENSG00000104635","Gene description":"Solute carrier family 39 member 14","Uniprot":["Q15043"],"Chromosome":"8","Position":"22367278-22434129","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":["Disease variant","Dystonia","Neurodegeneration","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"551.3","pancreas":"252.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Glandular and luminal cells":"266.7","Hepatocytes":"611.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+":"321.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016508","HPA056732"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1100000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":["Endoplasmic reticulum","Golgi apparatus","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA016508":"AB_1857148","HPA056732":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.00e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.83e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.79e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-3"},"Tissue RNA - adipose tissue [nTPM]":"63.5","Tissue RNA - adrenal gland [nTPM]":"72.4","Tissue RNA - amygdala [nTPM]":"13.0","Tissue RNA - appendix [nTPM]":"35.5","Tissue RNA - basal ganglia [nTPM]":"11.0","Tissue RNA - bone marrow [nTPM]":"1.4","Tissue RNA - breast [nTPM]":"39.8","Tissue RNA - cerebellum [nTPM]":"11.9","Tissue RNA - cerebral cortex [nTPM]":"13.1","Tissue RNA - cervix [nTPM]":"17.3","Tissue RNA - choroid plexus [nTPM]":"39.7","Tissue RNA - colon [nTPM]":"48.2","Tissue RNA - duodenum [nTPM]":"142.2","Tissue RNA - endometrium 1 [nTPM]":"30.2","Tissue RNA - epididymis [nTPM]":"6.2","Tissue RNA - esophagus [nTPM]":"11.6","Tissue RNA - fallopian tube [nTPM]":"25.9","Tissue RNA - gallbladder [nTPM]":"32.0","Tissue RNA - heart muscle [nTPM]":"76.7","Tissue RNA - hippocampal formation [nTPM]":"14.5","Tissue RNA - hypothalamus [nTPM]":"22.9","Tissue RNA - kidney [nTPM]":"30.8","Tissue RNA - liver [nTPM]":"551.3","Tissue RNA - lung [nTPM]":"23.9","Tissue RNA - lymph node [nTPM]":"7.6","Tissue RNA - medulla oblongata [nTPM]":"43.0","Tissue RNA - midbrain [nTPM]":"30.4","Tissue RNA - ovary [nTPM]":"27.7","Tissue RNA - pancreas [nTPM]":"252.7","Tissue RNA - parathyroid gland [nTPM]":"12.9","Tissue RNA - pituitary gland [nTPM]":"21.5","Tissue RNA - placenta [nTPM]":"19.0","Tissue RNA - pons [nTPM]":"25.7","Tissue RNA - prostate [nTPM]":"22.3","Tissue RNA - rectum [nTPM]":"50.3","Tissue RNA - retina [nTPM]":"18.6","Tissue RNA - salivary gland [nTPM]":"21.8","Tissue RNA - seminal vesicle [nTPM]":"18.7","Tissue RNA - skeletal muscle [nTPM]":"43.0","Tissue RNA - skin 1 [nTPM]":"20.0","Tissue RNA - small intestine [nTPM]":"84.9","Tissue RNA - smooth muscle [nTPM]":"33.0","Tissue RNA - spinal cord [nTPM]":"13.3","Tissue RNA - spleen [nTPM]":"8.1","Tissue RNA - stomach 1 [nTPM]":"80.5","Tissue RNA - testis [nTPM]":"26.5","Tissue RNA - thalamus [nTPM]":"25.3","Tissue RNA - thymus [nTPM]":"6.0","Tissue RNA - thyroid gland [nTPM]":"87.7","Tissue RNA - tongue [nTPM]":"17.4","Tissue RNA - tonsil [nTPM]":"6.9","Tissue RNA - urinary bladder [nTPM]":"56.0","Tissue RNA - vagina [nTPM]":"14.5","Tissue RNA - white matter [nTPM]":"14.8","Cell RNA - A-431 [nTPM]":"51.8","Cell RNA - A549 [nTPM]":"68.3","Cell RNA - AF22 [nTPM]":"18.4","Cell RNA - AN3-CA [nTPM]":"37.6","Cell RNA - ASC diff [nTPM]":"65.1","Cell RNA - ASC TERT1 [nTPM]":"54.7","Cell RNA - BEWO [nTPM]":"40.1","Cell RNA - BJ [nTPM]":"72.8","Cell RNA - BJ hTERT+ [nTPM]":"321.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"111.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"173.5","Cell RNA - CACO-2 [nTPM]":"226.9","Cell RNA - CAPAN-2 [nTPM]":"47.9","Cell RNA - Daudi [nTPM]":"51.1","Cell RNA - EFO-21 [nTPM]":"39.9","Cell RNA - fHDF\/TERT166 [nTPM]":"86.1","Cell RNA - GAMG [nTPM]":"288.9","Cell RNA - HaCaT [nTPM]":"55.6","Cell RNA - HAP1 [nTPM]":"92.8","Cell RNA - HBEC3-KT [nTPM]":"91.1","Cell RNA - HBF TERT88 [nTPM]":"181.9","Cell RNA - HDLM-2 [nTPM]":"53.1","Cell RNA - HEK 293 [nTPM]":"49.2","Cell RNA - HEL [nTPM]":"40.8","Cell RNA - HeLa [nTPM]":"51.0","Cell RNA - Hep G2 [nTPM]":"230.7","Cell RNA - HHSteC [nTPM]":"154.3","Cell RNA - HL-60 [nTPM]":"28.5","Cell RNA - HMC-1 [nTPM]":"43.2","Cell RNA - HSkMC [nTPM]":"58.4","Cell RNA - hTCEpi [nTPM]":"72.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"198.0","Cell RNA - hTERT-HME1 [nTPM]":"136.9","Cell RNA - hTERT-RPE1 [nTPM]":"56.3","Cell RNA - HUVEC TERT2 [nTPM]":"50.5","Cell RNA - JURKAT [nTPM]":"36.5","Cell RNA - K-562 [nTPM]":"36.2","Cell RNA - Karpas-707 [nTPM]":"51.2","Cell RNA - LHCN-M2 [nTPM]":"57.3","Cell RNA - MCF7 [nTPM]":"24.0","Cell RNA - MOLT-4 [nTPM]":"43.4","Cell RNA - NB-4 [nTPM]":"18.2","Cell RNA - NTERA-2 [nTPM]":"113.4","Cell RNA - OE19 [nTPM]":"81.9","Cell RNA - PC-3 [nTPM]":"49.8","Cell RNA - REH [nTPM]":"60.1","Cell RNA - RH-30 [nTPM]":"34.9","Cell RNA - RPMI-8226 [nTPM]":"110.8","Cell RNA - RPTEC TERT1 [nTPM]":"40.8","Cell RNA - RT4 [nTPM]":"22.3","Cell RNA - SCLC-21H [nTPM]":"31.3","Cell RNA - SH-SY5Y [nTPM]":"48.7","Cell RNA - SiHa [nTPM]":"74.3","Cell RNA - SK-BR-3 [nTPM]":"31.3","Cell RNA - SK-MEL-30 [nTPM]":"151.4","Cell RNA - SuSa [nTPM]":"39.7","Cell RNA - T-47d [nTPM]":"25.1","Cell RNA - THP-1 [nTPM]":"39.4","Cell RNA - TIME [nTPM]":"28.0","Cell RNA - U-138 MG [nTPM]":"137.3","Cell RNA - U-2 OS [nTPM]":"69.2","Cell RNA - U-2197 [nTPM]":"87.4","Cell RNA - U-251 MG [nTPM]":"75.7","Cell RNA - U-266\/70 [nTPM]":"29.2","Cell RNA - U-266\/84 [nTPM]":"28.7","Cell RNA - U-698 [nTPM]":"66.9","Cell RNA - U-87 MG [nTPM]":"194.3","Cell RNA - U-937 [nTPM]":"37.7","Cell RNA - WM-115 [nTPM]":"81.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"2.1","Blood RNA - gdT-cell [nTPM]":"6.7","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"7.2","Blood RNA - memory B-cell [nTPM]":"4.0","Blood RNA - memory CD4 T-cell [nTPM]":"3.8","Blood RNA - memory CD8 T-cell [nTPM]":"5.0","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"1.9","Blood RNA - naive CD4 T-cell [nTPM]":"4.3","Blood RNA - naive CD8 T-cell [nTPM]":"5.9","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"2.7","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"3.4","Blood RNA - total PBMC [nTPM]":"3.4","Brain RNA - amygdala [nTPM]":"13.0","Brain RNA - basal ganglia [nTPM]":"11.0","Brain RNA - cerebellum [nTPM]":"11.9","Brain RNA - cerebral cortex [nTPM]":"13.1","Brain RNA - hippocampal formation [nTPM]":"14.5","Brain RNA - hypothalamus [nTPM]":"22.9","Brain RNA - medulla oblongata [nTPM]":"43.0","Brain RNA - midbrain [nTPM]":"30.4","Brain RNA - pons [nTPM]":"25.7","Brain RNA - spinal cord [nTPM]":"13.3","Brain RNA - thalamus [nTPM]":"25.3","Brain RNA - white matter [nTPM]":"14.8","Single Cell Type RNA - Adipocytes [nTPM]":"12.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.7","Single Cell Type RNA - Astrocytes [nTPM]":"11.4","Single Cell Type RNA - B-cells [nTPM]":"9.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"33.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Bipolar cells [nTPM]":"7.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"20.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"66.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"41.5","Single Cell Type RNA - Club cells [nTPM]":"3.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"3.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"91.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"47.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"136.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"58.3","Single Cell Type RNA - Endothelial cells [nTPM]":"32.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"33.4","Single Cell Type RNA - Erythroid cells [nTPM]":"10.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"26.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"74.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.7","Single Cell Type RNA - Fibroblasts [nTPM]":"58.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"47.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"266.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"20.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"29.6","Single Cell Type RNA - Hepatocytes [nTPM]":"611.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.8","Single Cell Type RNA - Horizontal cells [nTPM]":"48.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"60.6","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"15.4","Single Cell Type RNA - Langerhans cells [nTPM]":"25.8","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"23.9","Single Cell Type RNA - Macrophages [nTPM]":"2.9","Single Cell Type RNA - Melanocytes [nTPM]":"44.4","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"2.7","Single Cell Type RNA - Muller glia cells [nTPM]":"5.2","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"47.3","Single Cell Type RNA - Paneth cells [nTPM]":"39.1","Single Cell Type RNA - Peritubular cells [nTPM]":"41.8","Single Cell Type RNA - Plasma cells [nTPM]":"13.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"26.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"75.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"24.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"47.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"3.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"7.4","Single Cell Type RNA - Theca cells [nTPM]":"14.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"43.5","Single Cell Type RNA - Urothelial cells [nTPM]":"9.4"},{"Gene":"SLC39A4","Gene synonym":["AEZ","AWMS2","ZIP4"],"Ensembl":"ENSG00000147804","Gene description":"Solute carrier family 39 member 4","Uniprot":["Q6P5W5"],"Chromosome":"8","Position":"144409742-144416844","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"88.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"406.4","Proximal tubular cells":"230.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"CAPAN-2":"36.4","Hep G2":"97.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.04e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.04e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"1.4","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.7","Tissue RNA - cervix [nTPM]":"0.7","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"33.1","Tissue RNA - duodenum [nTPM]":"88.1","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"18.4","Tissue RNA - liver [nTPM]":"1.3","Tissue RNA - lung [nTPM]":"3.1","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"3.3","Tissue RNA - pancreas [nTPM]":"1.4","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"1.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"1.3","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"1.2","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"74.9","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.7","Tissue RNA - stomach 1 [nTPM]":"2.9","Tissue RNA - testis [nTPM]":"1.3","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"3.9","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.6","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"2.3","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"2.5","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"2.1","Cell RNA - CAPAN-2 [nTPM]":"36.4","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"6.4","Cell RNA - HEK 293 [nTPM]":"0.8","Cell RNA - HEL [nTPM]":"1.6","Cell RNA - HeLa [nTPM]":"0.6","Cell RNA - Hep G2 [nTPM]":"97.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"2.5","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"1.5","Cell RNA - Karpas-707 [nTPM]":"2.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.7","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.5","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"0.9","Cell RNA - SH-SY5Y [nTPM]":"1.9","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"1.7","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.7","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"12.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"24.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"21.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"36.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"46.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"38.7","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"45.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"50.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"24.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"42.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"17.0","Single Cell Type RNA - dendritic cells [nTPM]":"15.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"112.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"50.9","Single Cell Type RNA - Ductal cells [nTPM]":"40.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"41.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.9","Single Cell Type RNA - Endothelial cells [nTPM]":"10.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"42.6","Single Cell Type RNA - Erythroid cells [nTPM]":"26.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"42.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"69.7","Single Cell Type RNA - Fibroblasts [nTPM]":"16.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"29.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"51.9","Single Cell Type RNA - granulocytes [nTPM]":"37.4","Single Cell Type RNA - Granulosa cells [nTPM]":"8.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.9","Single Cell Type RNA - Hepatocytes [nTPM]":"27.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"32.1","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"95.0","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"18.2","Single Cell Type RNA - Langerhans cells [nTPM]":"21.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.0","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"23.5","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"25.9","Single Cell Type RNA - Muller glia cells [nTPM]":"11.3","Single Cell Type RNA - NK-cells [nTPM]":"23.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"75.6","Single Cell Type RNA - Paneth cells [nTPM]":"135.0","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"31.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"60.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"406.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"230.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"26.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.1","Single Cell Type RNA - Spermatocytes [nTPM]":"2.9","Single Cell Type RNA - Spermatogonia [nTPM]":"33.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"46.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"30.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.2","Single Cell Type RNA - T-cells [nTPM]":"15.4","Single Cell Type RNA - Theca cells [nTPM]":"23.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"98.2","Single Cell Type RNA - Urothelial cells [nTPM]":"46.3"},{"Gene":"SLC39A5","Gene synonym":[],"Ensembl":"ENSG00000139540","Gene description":"Solute carrier family 39 member 5","Uniprot":["Q6ZMH5"],"Chromosome":"12","Position":"56230049-56237846","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"32","RNA tissue specific nTPM":{"intestine":"237.4","kidney":"110.0","liver":"171.1","pancreas":"306.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Proximal enterocytes":"798.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"30.6","liver cancer":"36.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"53","RNA cell line specific nTPM":{"CACO-2":"39.9","Hep G2":"58.5"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"1.1"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018423"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA018423":"AB_1857154"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-7"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.05e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-4"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"5.5","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"73.7","Tissue RNA - duodenum [nTPM]":"237.4","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"6.5","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"110.0","Tissue RNA - liver [nTPM]":"171.1","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"306.8","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"45.9","Tissue RNA - retina [nTPM]":"6.4","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"219.0","Tissue RNA - smooth muscle [nTPM]":"2.6","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"1.4","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"39.9","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.6","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"58.5","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.9","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.5","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"0.4","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"116.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"171.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"25.3","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"20.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"138.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"112.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.4","Single Cell Type RNA - Paneth cells [nTPM]":"192.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"798.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"169.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"168.7","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SLC39A8","Gene synonym":["BIGM103"],"Ensembl":"ENSG00000138821","Gene description":"Solute carrier family 39 member 8","Uniprot":["Q9C0K1"],"Chromosome":"4","Position":"102251041-102431258","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":["Congenital disorder of glycosylation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"171.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Alveolar cells type 1":"778.8","Alveolar cells type 2":"305.6","Extravillous trophoblasts":"217.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+":"158.9","HL-60":"120.9","Karpas-707":"171.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038832","HPA038833"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 19: Lung - Lung function","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 11: Alveolar cells - Smell perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038832":"AB_2676226","HPA038833":"AB_10670910"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.69e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.34e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.34e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.13e-3"},"Tissue RNA - adipose tissue [nTPM]":"45.5","Tissue RNA - adrenal gland [nTPM]":"3.5","Tissue RNA - amygdala [nTPM]":"9.6","Tissue RNA - appendix [nTPM]":"28.9","Tissue RNA - basal ganglia [nTPM]":"10.7","Tissue RNA - bone marrow [nTPM]":"36.5","Tissue RNA - breast [nTPM]":"18.1","Tissue RNA - cerebellum [nTPM]":"10.2","Tissue RNA - cerebral cortex [nTPM]":"12.1","Tissue RNA - cervix [nTPM]":"84.7","Tissue RNA - choroid plexus [nTPM]":"9.9","Tissue RNA - colon [nTPM]":"37.8","Tissue RNA - duodenum [nTPM]":"6.7","Tissue RNA - endometrium 1 [nTPM]":"11.0","Tissue RNA - epididymis [nTPM]":"5.7","Tissue RNA - esophagus [nTPM]":"3.0","Tissue RNA - fallopian tube [nTPM]":"11.9","Tissue RNA - gallbladder [nTPM]":"7.8","Tissue RNA - heart muscle [nTPM]":"30.4","Tissue RNA - hippocampal formation [nTPM]":"8.3","Tissue RNA - hypothalamus [nTPM]":"10.5","Tissue RNA - kidney [nTPM]":"18.3","Tissue RNA - liver [nTPM]":"40.0","Tissue RNA - lung [nTPM]":"171.1","Tissue RNA - lymph node [nTPM]":"13.3","Tissue RNA - medulla oblongata [nTPM]":"14.6","Tissue RNA - midbrain [nTPM]":"10.7","Tissue RNA - ovary [nTPM]":"14.0","Tissue RNA - pancreas [nTPM]":"54.5","Tissue RNA - parathyroid gland [nTPM]":"42.0","Tissue RNA - pituitary gland [nTPM]":"8.0","Tissue RNA - placenta [nTPM]":"13.0","Tissue RNA - pons [nTPM]":"14.4","Tissue RNA - prostate [nTPM]":"8.4","Tissue RNA - rectum [nTPM]":"43.0","Tissue RNA - retina [nTPM]":"6.4","Tissue RNA - salivary gland [nTPM]":"89.3","Tissue RNA - seminal vesicle [nTPM]":"6.6","Tissue RNA - skeletal muscle [nTPM]":"1.1","Tissue RNA - skin 1 [nTPM]":"9.4","Tissue RNA - small intestine [nTPM]":"7.3","Tissue RNA - smooth muscle [nTPM]":"9.1","Tissue RNA - spinal cord [nTPM]":"14.2","Tissue RNA - spleen [nTPM]":"6.7","Tissue RNA - stomach 1 [nTPM]":"7.8","Tissue RNA - testis [nTPM]":"2.6","Tissue RNA - thalamus [nTPM]":"13.5","Tissue RNA - thymus [nTPM]":"14.4","Tissue RNA - thyroid gland [nTPM]":"12.3","Tissue RNA - tongue [nTPM]":"2.0","Tissue RNA - tonsil [nTPM]":"12.3","Tissue RNA - urinary bladder [nTPM]":"20.8","Tissue RNA - vagina [nTPM]":"6.8","Tissue RNA - white matter [nTPM]":"11.6","Cell RNA - A-431 [nTPM]":"20.2","Cell RNA - A549 [nTPM]":"19.5","Cell RNA - AF22 [nTPM]":"4.4","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"15.8","Cell RNA - ASC TERT1 [nTPM]":"35.4","Cell RNA - BEWO [nTPM]":"10.1","Cell RNA - BJ [nTPM]":"2.2","Cell RNA - BJ hTERT+ [nTPM]":"158.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.3","Cell RNA - CACO-2 [nTPM]":"0.9","Cell RNA - CAPAN-2 [nTPM]":"72.5","Cell RNA - Daudi [nTPM]":"19.3","Cell RNA - EFO-21 [nTPM]":"21.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.6","Cell RNA - GAMG [nTPM]":"20.0","Cell RNA - HaCaT [nTPM]":"1.4","Cell RNA - HAP1 [nTPM]":"13.5","Cell RNA - HBEC3-KT [nTPM]":"4.4","Cell RNA - HBF TERT88 [nTPM]":"3.4","Cell RNA - HDLM-2 [nTPM]":"34.1","Cell RNA - HEK 293 [nTPM]":"39.5","Cell RNA - HEL [nTPM]":"51.0","Cell RNA - HeLa [nTPM]":"37.5","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"6.3","Cell RNA - HL-60 [nTPM]":"120.9","Cell RNA - HMC-1 [nTPM]":"16.8","Cell RNA - HSkMC [nTPM]":"19.1","Cell RNA - hTCEpi [nTPM]":"5.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.1","Cell RNA - hTERT-HME1 [nTPM]":"9.1","Cell RNA - hTERT-RPE1 [nTPM]":"15.4","Cell RNA - HUVEC TERT2 [nTPM]":"2.1","Cell RNA - JURKAT [nTPM]":"47.1","Cell RNA - K-562 [nTPM]":"51.6","Cell RNA - Karpas-707 [nTPM]":"171.2","Cell RNA - LHCN-M2 [nTPM]":"30.7","Cell RNA - MCF7 [nTPM]":"13.4","Cell RNA - MOLT-4 [nTPM]":"43.7","Cell RNA - NB-4 [nTPM]":"55.9","Cell RNA - NTERA-2 [nTPM]":"13.0","Cell RNA - OE19 [nTPM]":"26.8","Cell RNA - PC-3 [nTPM]":"19.0","Cell RNA - REH [nTPM]":"11.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"63.8","Cell RNA - RPTEC TERT1 [nTPM]":"33.3","Cell RNA - RT4 [nTPM]":"7.4","Cell RNA - SCLC-21H [nTPM]":"5.6","Cell RNA - SH-SY5Y [nTPM]":"14.0","Cell RNA - SiHa [nTPM]":"55.0","Cell RNA - SK-BR-3 [nTPM]":"1.0","Cell RNA - SK-MEL-30 [nTPM]":"5.3","Cell RNA - SuSa [nTPM]":"3.8","Cell RNA - T-47d [nTPM]":"13.4","Cell RNA - THP-1 [nTPM]":"44.4","Cell RNA - TIME [nTPM]":"11.3","Cell RNA - U-138 MG [nTPM]":"19.3","Cell RNA - U-2 OS [nTPM]":"7.3","Cell RNA - U-2197 [nTPM]":"39.1","Cell RNA - U-251 MG [nTPM]":"31.6","Cell RNA - U-266\/70 [nTPM]":"76.3","Cell RNA - U-266\/84 [nTPM]":"34.1","Cell RNA - U-698 [nTPM]":"90.4","Cell RNA - U-87 MG [nTPM]":"31.0","Cell RNA - U-937 [nTPM]":"77.4","Cell RNA - WM-115 [nTPM]":"18.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.8","Blood RNA - eosinophil [nTPM]":"1.4","Blood RNA - gdT-cell [nTPM]":"6.3","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"10.9","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"11.7","Blood RNA - memory CD8 T-cell [nTPM]":"10.0","Blood RNA - myeloid DC [nTPM]":"3.3","Blood RNA - naive B-cell [nTPM]":"3.9","Blood RNA - naive CD4 T-cell [nTPM]":"8.6","Blood RNA - naive CD8 T-cell [nTPM]":"5.9","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"13.7","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"5.0","Blood RNA - total PBMC [nTPM]":"4.2","Brain RNA - amygdala [nTPM]":"9.6","Brain RNA - basal ganglia [nTPM]":"10.7","Brain RNA - cerebellum [nTPM]":"10.2","Brain RNA - cerebral cortex [nTPM]":"12.1","Brain RNA - hippocampal formation [nTPM]":"8.3","Brain RNA - hypothalamus [nTPM]":"10.5","Brain RNA - medulla oblongata [nTPM]":"14.6","Brain RNA - midbrain [nTPM]":"10.7","Brain RNA - pons [nTPM]":"14.4","Brain RNA - spinal cord [nTPM]":"14.2","Brain RNA - thalamus [nTPM]":"13.5","Brain RNA - white matter [nTPM]":"11.6","Single Cell Type RNA - Adipocytes [nTPM]":"16.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"778.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"305.6","Single Cell Type RNA - Astrocytes [nTPM]":"15.7","Single Cell Type RNA - B-cells [nTPM]":"14.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"35.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"2.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"42.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"21.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"23.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.2","Single Cell Type RNA - dendritic cells [nTPM]":"14.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"20.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"1.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.2","Single Cell Type RNA - Endothelial cells [nTPM]":"19.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"24.0","Single Cell Type RNA - Erythroid cells [nTPM]":"46.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"32.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"217.5","Single Cell Type RNA - Fibroblasts [nTPM]":"17.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"40.9","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"32.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.7","Single Cell Type RNA - Hepatocytes [nTPM]":"26.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"42.9","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"74.1","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"29.8","Single Cell Type RNA - Langerhans cells [nTPM]":"79.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"28.9","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"60.9","Single Cell Type RNA - monocytes [nTPM]":"10.8","Single Cell Type RNA - Muller glia cells [nTPM]":"5.2","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.8","Single Cell Type RNA - Paneth cells [nTPM]":"26.2","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"56.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.8","Single Cell Type RNA - Spermatocytes [nTPM]":"2.3","Single Cell Type RNA - Spermatogonia [nTPM]":"6.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"60.6","Single Cell Type RNA - T-cells [nTPM]":"23.6","Single Cell Type RNA - Theca cells [nTPM]":"31.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"64.3","Single Cell Type RNA - Urothelial cells [nTPM]":"6.8"},{"Gene":"SLC3A1","Gene synonym":["ATR1","CSNU1","D2H","NBAT","RBAT"],"Ensembl":"ENSG00000138079","Gene description":"Solute carrier family 3 member 1","Uniprot":["Q07837"],"Chromosome":"2","Position":"44275458-44321494","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Transport"],"Molecular function":null,"Disease involvement":["Cystinuria","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"136.2","kidney":"649.3","pancreas":"217.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"74.4","Glandular and luminal cells":"128.9","Proximal enterocytes":"258.9","Proximal tubular cells":"363.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"renal cancer":"61.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"22","RNA cell line specific nTPM":{"RPTEC TERT1":"106.1"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038360","HPA071102"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA038360":"AB_2675975","HPA071102":"AB_2732171"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.67e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-4"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"1.2","Tissue RNA - appendix [nTPM]":"1.1","Tissue RNA - basal ganglia [nTPM]":"1.7","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"6.8","Tissue RNA - cerebral cortex [nTPM]":"3.4","Tissue RNA - cervix [nTPM]":"1.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"22.4","Tissue RNA - duodenum [nTPM]":"113.9","Tissue RNA - endometrium 1 [nTPM]":"1.4","Tissue RNA - epididymis [nTPM]":"1.9","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.6","Tissue RNA - gallbladder [nTPM]":"51.5","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"1.6","Tissue RNA - hypothalamus [nTPM]":"1.3","Tissue RNA - kidney [nTPM]":"649.3","Tissue RNA - liver [nTPM]":"36.6","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"0.6","Tissue RNA - midbrain [nTPM]":"0.6","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"217.5","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.7","Tissue RNA - prostate [nTPM]":"1.0","Tissue RNA - rectum [nTPM]":"22.7","Tissue RNA - retina [nTPM]":"3.5","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"1.0","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"136.2","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"0.9","Tissue RNA - testis [nTPM]":"1.7","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"1.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"1.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"4.9","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"4.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"1.2","Cell RNA - PC-3 [nTPM]":"0.5","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"106.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"1.2","Brain RNA - basal ganglia [nTPM]":"1.7","Brain RNA - cerebellum [nTPM]":"6.8","Brain RNA - cerebral cortex [nTPM]":"3.4","Brain RNA - hippocampal formation [nTPM]":"1.6","Brain RNA - hypothalamus [nTPM]":"1.3","Brain RNA - medulla oblongata [nTPM]":"0.6","Brain RNA - midbrain [nTPM]":"0.6","Brain RNA - pons [nTPM]":"0.7","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"1.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"6.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"12.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"74.4","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"42.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"62.6","Single Cell Type RNA - Ductal cells [nTPM]":"37.0","Single Cell Type RNA - Early spermatids [nTPM]":"12.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"62.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"128.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"4.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"8.5","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"3.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"1.6","Single Cell Type RNA - Muller glia cells [nTPM]":"1.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.8","Single Cell Type RNA - Paneth cells [nTPM]":"18.6","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"1.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"258.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"363.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"2.8","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.7","Single Cell Type RNA - Urothelial cells [nTPM]":"1.2"},{"Gene":"SLC40A1","Gene synonym":["FPN1","HFE4","IREG1","MTP1","SLC11A3"],"Ensembl":"ENSG00000138449","Gene description":"Solute carrier family 40 member 1","Uniprot":["Q9NP59"],"Chromosome":"2","Position":"189560590-189583758","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Iron transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"489.8","Kupffer cells":"1340.2","Syncytiotrophoblasts":"2463.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"326.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"509.0","CACO-2":"123.1","HEL":"430.0","HMC-1":"110.5","T-47d":"207.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065634"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 14: B-cells - Humoral immune response","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA065634":"AB_2685524"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.00e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.55e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Tissue RNA - adipose tissue [nTPM]":"59.6","Tissue RNA - adrenal gland [nTPM]":"333.5","Tissue RNA - amygdala [nTPM]":"9.3","Tissue RNA - appendix [nTPM]":"52.6","Tissue RNA - basal ganglia [nTPM]":"11.9","Tissue RNA - bone marrow [nTPM]":"45.8","Tissue RNA - breast [nTPM]":"97.7","Tissue RNA - cerebellum [nTPM]":"9.6","Tissue RNA - cerebral cortex [nTPM]":"9.8","Tissue RNA - cervix [nTPM]":"156.3","Tissue RNA - choroid plexus [nTPM]":"10.4","Tissue RNA - colon [nTPM]":"124.7","Tissue RNA - duodenum [nTPM]":"289.3","Tissue RNA - endometrium 1 [nTPM]":"95.4","Tissue RNA - epididymis [nTPM]":"61.6","Tissue RNA - esophagus [nTPM]":"30.5","Tissue RNA - fallopian tube [nTPM]":"214.2","Tissue RNA - gallbladder [nTPM]":"148.7","Tissue RNA - heart muscle [nTPM]":"52.6","Tissue RNA - hippocampal formation [nTPM]":"7.2","Tissue RNA - hypothalamus [nTPM]":"12.0","Tissue RNA - kidney [nTPM]":"79.9","Tissue RNA - liver [nTPM]":"251.5","Tissue RNA - lung [nTPM]":"122.9","Tissue RNA - lymph node [nTPM]":"172.6","Tissue RNA - medulla oblongata [nTPM]":"15.6","Tissue RNA - midbrain [nTPM]":"15.7","Tissue RNA - ovary [nTPM]":"317.2","Tissue RNA - pancreas [nTPM]":"53.2","Tissue RNA - parathyroid gland [nTPM]":"91.8","Tissue RNA - pituitary gland [nTPM]":"19.0","Tissue RNA - placenta [nTPM]":"250.1","Tissue RNA - pons [nTPM]":"12.8","Tissue RNA - prostate [nTPM]":"39.5","Tissue RNA - rectum [nTPM]":"130.8","Tissue RNA - retina [nTPM]":"29.5","Tissue RNA - salivary gland [nTPM]":"58.7","Tissue RNA - seminal vesicle [nTPM]":"53.1","Tissue RNA - skeletal muscle [nTPM]":"64.2","Tissue RNA - skin 1 [nTPM]":"12.2","Tissue RNA - small intestine [nTPM]":"127.9","Tissue RNA - smooth muscle [nTPM]":"69.3","Tissue RNA - spinal cord [nTPM]":"15.5","Tissue RNA - spleen [nTPM]":"368.1","Tissue RNA - stomach 1 [nTPM]":"96.8","Tissue RNA - testis [nTPM]":"33.2","Tissue RNA - thalamus [nTPM]":"13.9","Tissue RNA - thymus [nTPM]":"62.6","Tissue RNA - thyroid gland [nTPM]":"68.0","Tissue RNA - tongue [nTPM]":"60.3","Tissue RNA - tonsil [nTPM]":"59.1","Tissue RNA - urinary bladder [nTPM]":"53.1","Tissue RNA - vagina [nTPM]":"21.8","Tissue RNA - white matter [nTPM]":"11.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"7.4","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"509.0","Cell RNA - ASC TERT1 [nTPM]":"3.3","Cell RNA - BEWO [nTPM]":"25.4","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"6.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.1","Cell RNA - CACO-2 [nTPM]":"123.1","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"1.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"1.4","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"2.4","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"1.6","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"1.7","Cell RNA - HEL [nTPM]":"430.0","Cell RNA - HeLa [nTPM]":"1.7","Cell RNA - Hep G2 [nTPM]":"45.8","Cell RNA - HHSteC [nTPM]":"1.9","Cell RNA - HL-60 [nTPM]":"1.5","Cell RNA - HMC-1 [nTPM]":"110.5","Cell RNA - HSkMC [nTPM]":"35.9","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"11.7","Cell RNA - HUVEC TERT2 [nTPM]":"13.0","Cell RNA - JURKAT [nTPM]":"16.4","Cell RNA - K-562 [nTPM]":"44.6","Cell RNA - Karpas-707 [nTPM]":"1.1","Cell RNA - LHCN-M2 [nTPM]":"6.3","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"18.2","Cell RNA - NB-4 [nTPM]":"28.8","Cell RNA - NTERA-2 [nTPM]":"1.5","Cell RNA - OE19 [nTPM]":"92.7","Cell RNA - PC-3 [nTPM]":"1.7","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"5.0","Cell RNA - RPMI-8226 [nTPM]":"2.5","Cell RNA - RPTEC TERT1 [nTPM]":"5.3","Cell RNA - RT4 [nTPM]":"18.1","Cell RNA - SCLC-21H [nTPM]":"1.0","Cell RNA - SH-SY5Y [nTPM]":"5.4","Cell RNA - SiHa [nTPM]":"0.8","Cell RNA - SK-BR-3 [nTPM]":"35.4","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"39.5","Cell RNA - T-47d [nTPM]":"207.6","Cell RNA - THP-1 [nTPM]":"6.2","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.8","Cell RNA - U-2 OS [nTPM]":"11.7","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"1.1","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"129.8","Blood RNA - classical monocyte [nTPM]":"101.5","Blood RNA - eosinophil [nTPM]":"172.1","Blood RNA - gdT-cell [nTPM]":"2.2","Blood RNA - intermediate monocyte [nTPM]":"23.7","Blood RNA - MAIT T-cell [nTPM]":"3.2","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"54.4","Blood RNA - memory CD8 T-cell [nTPM]":"4.9","Blood RNA - myeloid DC [nTPM]":"115.6","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"80.2","Blood RNA - naive CD8 T-cell [nTPM]":"17.8","Blood RNA - neutrophil [nTPM]":"326.2","Blood RNA - NK-cell [nTPM]":"4.6","Blood RNA - non-classical monocyte [nTPM]":"2.6","Blood RNA - plasmacytoid DC [nTPM]":"18.8","Blood RNA - T-reg [nTPM]":"5.3","Blood RNA - total PBMC [nTPM]":"105.8","Brain RNA - amygdala [nTPM]":"9.3","Brain RNA - basal ganglia [nTPM]":"11.9","Brain RNA - cerebellum [nTPM]":"9.6","Brain RNA - cerebral cortex [nTPM]":"9.8","Brain RNA - hippocampal formation [nTPM]":"7.2","Brain RNA - hypothalamus [nTPM]":"12.0","Brain RNA - medulla oblongata [nTPM]":"15.6","Brain RNA - midbrain [nTPM]":"15.7","Brain RNA - pons [nTPM]":"12.8","Brain RNA - spinal cord [nTPM]":"15.5","Brain RNA - thalamus [nTPM]":"13.9","Brain RNA - white matter [nTPM]":"11.3","Single Cell Type RNA - Adipocytes [nTPM]":"44.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"125.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"40.3","Single Cell Type RNA - Astrocytes [nTPM]":"3.6","Single Cell Type RNA - B-cells [nTPM]":"12.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"51.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.9","Single Cell Type RNA - Bipolar cells [nTPM]":"4.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"83.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"48.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"138.7","Single Cell Type RNA - Club cells [nTPM]":"31.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"489.8","Single Cell Type RNA - dendritic cells [nTPM]":"5.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"328.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"49.0","Single Cell Type RNA - Ductal cells [nTPM]":"54.7","Single Cell Type RNA - Early spermatids [nTPM]":"10.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"39.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"38.2","Single Cell Type RNA - Endothelial cells [nTPM]":"39.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.6","Single Cell Type RNA - Erythroid cells [nTPM]":"253.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"71.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.3","Single Cell Type RNA - Fibroblasts [nTPM]":"81.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"76.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"129.5","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"12.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"245.9","Single Cell Type RNA - Hepatocytes [nTPM]":"259.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"86.4","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"60.8","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"1340.2","Single Cell Type RNA - Langerhans cells [nTPM]":"26.8","Single Cell Type RNA - Late spermatids [nTPM]":"9.2","Single Cell Type RNA - Leydig cells [nTPM]":"121.2","Single Cell Type RNA - Macrophages [nTPM]":"172.7","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"34.7","Single Cell Type RNA - monocytes [nTPM]":"41.7","Single Cell Type RNA - Muller glia cells [nTPM]":"17.5","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"71.5","Single Cell Type RNA - Paneth cells [nTPM]":"86.2","Single Cell Type RNA - Peritubular cells [nTPM]":"58.6","Single Cell Type RNA - Plasma cells [nTPM]":"4.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"26.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"163.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"150.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"34.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"48.4","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"49.1","Single Cell Type RNA - Spermatocytes [nTPM]":"7.4","Single Cell Type RNA - Spermatogonia [nTPM]":"3.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2463.5","Single Cell Type RNA - T-cells [nTPM]":"11.9","Single Cell Type RNA - Theca cells [nTPM]":"84.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"48.9","Single Cell Type RNA - Urothelial cells [nTPM]":"27.7"},{"Gene":"SLC44A1","Gene synonym":["CD92","CDW92","CHTL1","CTL1"],"Ensembl":"ENSG00000070214","Gene description":"Solute carrier family 44 member 1","Uniprot":["Q8WWI5"],"Chromosome":"9","Position":"105244622-105439171","Protein class":["CD markers","Disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"284.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Oligodendrocytes":"2444.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"285.9","ASC TERT1":"224.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064714","HPA074007"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"99000","Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA064714":"AB_2685334","HPA074007":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.49e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.85e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Tissue RNA - adipose tissue [nTPM]":"16.9","Tissue RNA - adrenal gland [nTPM]":"13.3","Tissue RNA - amygdala [nTPM]":"112.9","Tissue RNA - appendix [nTPM]":"12.9","Tissue RNA - basal ganglia [nTPM]":"204.4","Tissue RNA - bone marrow [nTPM]":"11.4","Tissue RNA - breast [nTPM]":"26.2","Tissue RNA - cerebellum [nTPM]":"166.7","Tissue RNA - cerebral cortex [nTPM]":"138.7","Tissue RNA - cervix [nTPM]":"16.7","Tissue RNA - choroid plexus [nTPM]":"79.4","Tissue RNA - colon [nTPM]":"50.2","Tissue RNA - duodenum [nTPM]":"22.6","Tissue RNA - endometrium 1 [nTPM]":"15.9","Tissue RNA - epididymis [nTPM]":"32.4","Tissue RNA - esophagus [nTPM]":"18.4","Tissue RNA - fallopian tube [nTPM]":"15.2","Tissue RNA - gallbladder [nTPM]":"20.2","Tissue RNA - heart muscle [nTPM]":"12.7","Tissue RNA - hippocampal formation [nTPM]":"116.2","Tissue RNA - hypothalamus [nTPM]":"136.1","Tissue RNA - kidney [nTPM]":"21.8","Tissue RNA - liver [nTPM]":"38.0","Tissue RNA - lung [nTPM]":"18.4","Tissue RNA - lymph node [nTPM]":"9.7","Tissue RNA - medulla oblongata [nTPM]":"204.3","Tissue RNA - midbrain [nTPM]":"167.7","Tissue RNA - ovary [nTPM]":"14.1","Tissue RNA - pancreas [nTPM]":"15.1","Tissue RNA - parathyroid gland [nTPM]":"23.2","Tissue RNA - pituitary gland [nTPM]":"5.3","Tissue RNA - placenta [nTPM]":"23.3","Tissue RNA - pons [nTPM]":"205.5","Tissue RNA - prostate [nTPM]":"11.8","Tissue RNA - rectum [nTPM]":"49.0","Tissue RNA - retina [nTPM]":"14.1","Tissue RNA - salivary gland [nTPM]":"9.6","Tissue RNA - seminal vesicle [nTPM]":"25.0","Tissue RNA - skeletal muscle [nTPM]":"9.4","Tissue RNA - skin 1 [nTPM]":"21.5","Tissue RNA - small intestine [nTPM]":"27.0","Tissue RNA - smooth muscle [nTPM]":"17.3","Tissue RNA - spinal cord [nTPM]":"161.1","Tissue RNA - spleen [nTPM]":"9.5","Tissue RNA - stomach 1 [nTPM]":"35.2","Tissue RNA - testis [nTPM]":"3.5","Tissue RNA - thalamus [nTPM]":"150.8","Tissue RNA - thymus [nTPM]":"13.6","Tissue RNA - thyroid gland [nTPM]":"43.6","Tissue RNA - tongue [nTPM]":"20.2","Tissue RNA - tonsil [nTPM]":"15.5","Tissue RNA - urinary bladder [nTPM]":"21.8","Tissue RNA - vagina [nTPM]":"15.6","Tissue RNA - white matter [nTPM]":"284.9","Cell RNA - A-431 [nTPM]":"29.0","Cell RNA - A549 [nTPM]":"23.8","Cell RNA - AF22 [nTPM]":"6.4","Cell RNA - AN3-CA [nTPM]":"7.9","Cell RNA - ASC diff [nTPM]":"285.9","Cell RNA - ASC TERT1 [nTPM]":"224.1","Cell RNA - BEWO [nTPM]":"20.3","Cell RNA - BJ [nTPM]":"23.9","Cell RNA - BJ hTERT+ [nTPM]":"61.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.2","Cell RNA - CACO-2 [nTPM]":"25.6","Cell RNA - CAPAN-2 [nTPM]":"74.8","Cell RNA - Daudi [nTPM]":"38.4","Cell RNA - EFO-21 [nTPM]":"12.0","Cell RNA - fHDF\/TERT166 [nTPM]":"90.2","Cell RNA - GAMG [nTPM]":"17.1","Cell RNA - HaCaT [nTPM]":"56.1","Cell RNA - HAP1 [nTPM]":"19.3","Cell RNA - HBEC3-KT [nTPM]":"34.4","Cell RNA - HBF TERT88 [nTPM]":"25.7","Cell RNA - HDLM-2 [nTPM]":"34.0","Cell RNA - HEK 293 [nTPM]":"15.7","Cell RNA - HEL [nTPM]":"47.8","Cell RNA - HeLa [nTPM]":"15.8","Cell RNA - Hep G2 [nTPM]":"32.0","Cell RNA - HHSteC [nTPM]":"19.3","Cell RNA - HL-60 [nTPM]":"9.6","Cell RNA - HMC-1 [nTPM]":"23.7","Cell RNA - HSkMC [nTPM]":"125.3","Cell RNA - hTCEpi [nTPM]":"27.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"29.0","Cell RNA - hTERT-HME1 [nTPM]":"26.1","Cell RNA - hTERT-RPE1 [nTPM]":"38.8","Cell RNA - HUVEC TERT2 [nTPM]":"48.6","Cell RNA - JURKAT [nTPM]":"19.7","Cell RNA - K-562 [nTPM]":"1.4","Cell RNA - Karpas-707 [nTPM]":"77.1","Cell RNA - LHCN-M2 [nTPM]":"17.3","Cell RNA - MCF7 [nTPM]":"40.8","Cell RNA - MOLT-4 [nTPM]":"38.8","Cell RNA - NB-4 [nTPM]":"10.9","Cell RNA - NTERA-2 [nTPM]":"35.9","Cell RNA - OE19 [nTPM]":"51.1","Cell RNA - PC-3 [nTPM]":"22.9","Cell RNA - REH [nTPM]":"8.0","Cell RNA - RH-30 [nTPM]":"24.7","Cell RNA - RPMI-8226 [nTPM]":"29.3","Cell RNA - RPTEC TERT1 [nTPM]":"20.9","Cell RNA - RT4 [nTPM]":"66.6","Cell RNA - SCLC-21H [nTPM]":"30.6","Cell RNA - SH-SY5Y [nTPM]":"12.0","Cell RNA - SiHa [nTPM]":"33.4","Cell RNA - SK-BR-3 [nTPM]":"36.5","Cell RNA - SK-MEL-30 [nTPM]":"33.3","Cell RNA - SuSa [nTPM]":"37.8","Cell RNA - T-47d [nTPM]":"36.2","Cell RNA - THP-1 [nTPM]":"28.7","Cell RNA - TIME [nTPM]":"41.9","Cell RNA - U-138 MG [nTPM]":"15.1","Cell RNA - U-2 OS [nTPM]":"13.5","Cell RNA - U-2197 [nTPM]":"16.5","Cell RNA - U-251 MG [nTPM]":"17.7","Cell RNA - U-266\/70 [nTPM]":"59.1","Cell RNA - U-266\/84 [nTPM]":"41.7","Cell RNA - U-698 [nTPM]":"28.4","Cell RNA - U-87 MG [nTPM]":"29.2","Cell RNA - U-937 [nTPM]":"20.6","Cell RNA - WM-115 [nTPM]":"20.2","Blood RNA - basophil [nTPM]":"1.7","Blood RNA - classical monocyte [nTPM]":"3.3","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"1.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.7","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"2.2","Blood RNA - naive B-cell [nTPM]":"2.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"5.3","Blood RNA - non-classical monocyte [nTPM]":"0.7","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"112.9","Brain RNA - basal ganglia [nTPM]":"204.4","Brain RNA - cerebellum [nTPM]":"166.7","Brain RNA - cerebral cortex [nTPM]":"138.7","Brain RNA - hippocampal formation [nTPM]":"116.2","Brain RNA - hypothalamus [nTPM]":"136.1","Brain RNA - medulla oblongata [nTPM]":"204.3","Brain RNA - midbrain [nTPM]":"167.7","Brain RNA - pons [nTPM]":"205.5","Brain RNA - spinal cord [nTPM]":"161.1","Brain RNA - thalamus [nTPM]":"150.8","Brain RNA - white matter [nTPM]":"284.9","Single Cell Type RNA - Adipocytes [nTPM]":"48.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.5","Single Cell Type RNA - Astrocytes [nTPM]":"83.2","Single Cell Type RNA - B-cells [nTPM]":"22.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"70.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"36.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"28.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"75.1","Single Cell Type RNA - Bipolar cells [nTPM]":"10.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"76.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"27.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"67.2","Single Cell Type RNA - Club cells [nTPM]":"19.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"106.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"235.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"53.3","Single Cell Type RNA - dendritic cells [nTPM]":"7.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"296.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"17.5","Single Cell Type RNA - Early spermatids [nTPM]":"2.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"59.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"40.3","Single Cell Type RNA - Endothelial cells [nTPM]":"45.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"157.2","Single Cell Type RNA - Erythroid cells [nTPM]":"20.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"174.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"36.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.1","Single Cell Type RNA - Fibroblasts [nTPM]":"64.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"84.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"175.2","Single Cell Type RNA - granulocytes [nTPM]":"100.1","Single Cell Type RNA - Granulosa cells [nTPM]":"16.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"48.9","Single Cell Type RNA - Hepatocytes [nTPM]":"170.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"21.3","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"108.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"160.0","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"46.5","Single Cell Type RNA - Langerhans cells [nTPM]":"46.5","Single Cell Type RNA - Late spermatids [nTPM]":"6.1","Single Cell Type RNA - Leydig cells [nTPM]":"110.0","Single Cell Type RNA - Macrophages [nTPM]":"48.6","Single Cell Type RNA - Melanocytes [nTPM]":"74.7","Single Cell Type RNA - Microglial cells [nTPM]":"81.5","Single Cell Type RNA - monocytes [nTPM]":"91.0","Single Cell Type RNA - Muller glia cells [nTPM]":"9.0","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"257.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2444.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"36.9","Single Cell Type RNA - Paneth cells [nTPM]":"161.2","Single Cell Type RNA - Peritubular cells [nTPM]":"79.7","Single Cell Type RNA - Plasma cells [nTPM]":"162.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"95.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"27.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"31.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"53.3","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"43.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"34.9","Single Cell Type RNA - Spermatocytes [nTPM]":"2.3","Single Cell Type RNA - Spermatogonia [nTPM]":"4.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"86.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"74.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"70.6","Single Cell Type RNA - T-cells [nTPM]":"20.3","Single Cell Type RNA - Theca cells [nTPM]":"12.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"199.1","Single Cell Type RNA - Urothelial cells [nTPM]":"34.8"},{"Gene":"SLC44A4","Gene synonym":["C6orf29","CTL4","DFNA72","FLJ14491","NG22","TPPT"],"Ensembl":"ENSG00000204385","Gene description":"Solute carrier family 44 member 4","Uniprot":["Q53GD3"],"Chromosome":"6","Position":"31863192-31879046","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"132.0","prostate":"83.0","stomach 1":"83.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"546.0","Exocrine glandular cells":"213.4","Intestinal goblet cells":"327.8","Paneth cells":"299.3","Proximal enterocytes":"267.7","Respiratory ciliated cells":"406.7","Undifferentiated cells":"259.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"222.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"OE19":"14.6"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046977","HPA054176"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046977":"AB_2679887","HPA054176":"AB_2682404"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.54e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.06e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.06e-4"},"Tissue RNA - adipose tissue [nTPM]":"0.8","Tissue RNA - adrenal gland [nTPM]":"8.2","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"2.5","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"1.0","Tissue RNA - breast [nTPM]":"5.3","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"22.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"132.0","Tissue RNA - duodenum [nTPM]":"100.8","Tissue RNA - endometrium 1 [nTPM]":"5.9","Tissue RNA - epididymis [nTPM]":"2.5","Tissue RNA - esophagus [nTPM]":"2.0","Tissue RNA - fallopian tube [nTPM]":"46.9","Tissue RNA - gallbladder [nTPM]":"18.8","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"32.1","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"14.9","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"1.6","Tissue RNA - pancreas [nTPM]":"8.9","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"16.1","Tissue RNA - placenta [nTPM]":"3.5","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"83.0","Tissue RNA - rectum [nTPM]":"30.3","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"42.6","Tissue RNA - seminal vesicle [nTPM]":"3.9","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"1.1","Tissue RNA - small intestine [nTPM]":"86.8","Tissue RNA - smooth muscle [nTPM]":"2.9","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"1.6","Tissue RNA - stomach 1 [nTPM]":"83.4","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"1.9","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.7","Tissue RNA - urinary bladder [nTPM]":"11.0","Tissue RNA - vagina [nTPM]":"1.8","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"1.3","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"1.7","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"14.6","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.7","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.7","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"3.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"36.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"3.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"71.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"180.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"66.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"546.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"111.2","Single Cell Type RNA - Early spermatids [nTPM]":"2.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"127.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.9","Single Cell Type RNA - Endothelial cells [nTPM]":"6.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"46.7","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"213.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"2.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"208.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"67.5","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"1.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"327.8","Single Cell Type RNA - Ionocytes [nTPM]":"91.6","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"2.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"184.0","Single Cell Type RNA - Paneth cells [nTPM]":"299.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"142.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"267.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"61.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"406.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"2.3","Single Cell Type RNA - Theca cells [nTPM]":"5.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"259.6","Single Cell Type RNA - Urothelial cells [nTPM]":"139.4"},{"Gene":"SLC45A1","Gene synonym":["DNB5"],"Ensembl":"ENSG00000162426","Gene description":"Solute carrier family 45 member 1","Uniprot":["Q9Y2W3"],"Chromosome":"1","Position":"8318114-8344167","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"10.0","Horizontal cells":"10.1","Inhibitory neurons":"11.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"4.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"non-classical monocyte":"3.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"monocytes":"3.9"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"3.7","GAMG":"2.7","HHSteC":"4.9","U-87 MG":"6.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078818"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA078818":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-3"},"Tissue RNA - adipose tissue [nTPM]":"2.2","Tissue RNA - adrenal gland [nTPM]":"1.8","Tissue RNA - amygdala [nTPM]":"3.4","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"3.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"2.1","Tissue RNA - cerebellum [nTPM]":"2.6","Tissue RNA - cerebral cortex [nTPM]":"5.6","Tissue RNA - cervix [nTPM]":"3.5","Tissue RNA - choroid plexus [nTPM]":"1.9","Tissue RNA - colon [nTPM]":"4.0","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"5.1","Tissue RNA - epididymis [nTPM]":"0.8","Tissue RNA - esophagus [nTPM]":"0.9","Tissue RNA - fallopian tube [nTPM]":"4.3","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"1.9","Tissue RNA - hippocampal formation [nTPM]":"3.4","Tissue RNA - hypothalamus [nTPM]":"3.7","Tissue RNA - kidney [nTPM]":"4.2","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.9","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"5.0","Tissue RNA - midbrain [nTPM]":"3.3","Tissue RNA - ovary [nTPM]":"3.0","Tissue RNA - pancreas [nTPM]":"1.0","Tissue RNA - parathyroid gland [nTPM]":"1.1","Tissue RNA - pituitary gland [nTPM]":"6.7","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"6.0","Tissue RNA - prostate [nTPM]":"2.9","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"1.6","Tissue RNA - salivary gland [nTPM]":"0.9","Tissue RNA - seminal vesicle [nTPM]":"2.1","Tissue RNA - skeletal muscle [nTPM]":"1.2","Tissue RNA - skin 1 [nTPM]":"0.8","Tissue RNA - small intestine [nTPM]":"1.9","Tissue RNA - smooth muscle [nTPM]":"1.1","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"1.4","Tissue RNA - stomach 1 [nTPM]":"1.7","Tissue RNA - testis [nTPM]":"1.4","Tissue RNA - thalamus [nTPM]":"3.9","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"1.4","Tissue RNA - tongue [nTPM]":"1.3","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"3.0","Tissue RNA - vagina [nTPM]":"2.6","Tissue RNA - white matter [nTPM]":"2.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"1.8","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.8","Cell RNA - ASC diff [nTPM]":"3.7","Cell RNA - ASC TERT1 [nTPM]":"2.6","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.5","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.5","Cell RNA - GAMG [nTPM]":"2.7","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"1.5","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"4.9","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.4","Cell RNA - HSkMC [nTPM]":"1.2","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.6","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.4","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.9","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.9","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"1.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.8","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.3","Cell RNA - SH-SY5Y [nTPM]":"1.8","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"1.7","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"1.5","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"6.5","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"3.9","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"3.4","Brain RNA - basal ganglia [nTPM]":"3.3","Brain RNA - cerebellum [nTPM]":"2.6","Brain RNA - cerebral cortex [nTPM]":"5.6","Brain RNA - hippocampal formation [nTPM]":"3.4","Brain RNA - hypothalamus [nTPM]":"3.7","Brain RNA - medulla oblongata [nTPM]":"5.0","Brain RNA - midbrain [nTPM]":"3.3","Brain RNA - pons [nTPM]":"6.0","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"3.9","Brain RNA - white matter [nTPM]":"2.9","Single Cell Type RNA - Adipocytes [nTPM]":"6.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"7.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.6","Single Cell Type RNA - Early spermatids [nTPM]":"2.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.4","Single Cell Type RNA - Endothelial cells [nTPM]":"2.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"3.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1.5","Single Cell Type RNA - Late spermatids [nTPM]":"5.4","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"6.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"5.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"1.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"SLC45A2","Gene synonym":["AIM-1","MATP","OCA4"],"Ensembl":"ENSG00000164175","Gene description":"Solute carrier family 45 member 2","Uniprot":["Q9UMX9"],"Chromosome":"5","Position":"33944623-33984693","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Melanin biosynthesis","Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Albinism","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"1.2","skin 1":"1.0","testis":"1.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"3.1","Excitatory neurons":"4.1","Inhibitory neurons":"5.4","Late spermatids":"5.1","Melanocytes":"12.4","Oligodendrocyte precursor cells":"2.5","Oligodendrocytes":"4.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"18","RNA cancer specific FPKM":{"melanoma":"47.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"28","RNA cell line specific nTPM":{"SK-MEL-30":"60.3"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"1.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"2.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"60.3","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"1.5","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"3.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"5.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SLC46A1","Gene synonym":["HCP1","MGC9564","PCFT"],"Ensembl":"ENSG00000076351","Gene description":"Solute carrier family 46 member 1","Uniprot":["Q96NT5"],"Chromosome":"17","Position":"28394642-28407197","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"93.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"26.6","Hepatocytes":"27.8","Hofbauer cells":"25.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"CACO-2":"205.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011614"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB011614":"AB_2270597"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.62e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.7","Tissue RNA - adrenal gland [nTPM]":"24.8","Tissue RNA - amygdala [nTPM]":"8.1","Tissue RNA - appendix [nTPM]":"5.7","Tissue RNA - basal ganglia [nTPM]":"10.6","Tissue RNA - bone marrow [nTPM]":"3.4","Tissue RNA - breast [nTPM]":"5.7","Tissue RNA - cerebellum [nTPM]":"14.7","Tissue RNA - cerebral cortex [nTPM]":"9.2","Tissue RNA - cervix [nTPM]":"5.6","Tissue RNA - choroid plexus [nTPM]":"26.7","Tissue RNA - colon [nTPM]":"5.7","Tissue RNA - duodenum [nTPM]":"93.9","Tissue RNA - endometrium 1 [nTPM]":"4.6","Tissue RNA - epididymis [nTPM]":"8.5","Tissue RNA - esophagus [nTPM]":"2.4","Tissue RNA - fallopian tube [nTPM]":"13.4","Tissue RNA - gallbladder [nTPM]":"4.6","Tissue RNA - heart muscle [nTPM]":"4.6","Tissue RNA - hippocampal formation [nTPM]":"8.0","Tissue RNA - hypothalamus [nTPM]":"8.4","Tissue RNA - kidney [nTPM]":"7.5","Tissue RNA - liver [nTPM]":"27.3","Tissue RNA - lung [nTPM]":"6.9","Tissue RNA - lymph node [nTPM]":"5.5","Tissue RNA - medulla oblongata [nTPM]":"11.2","Tissue RNA - midbrain [nTPM]":"9.7","Tissue RNA - ovary [nTPM]":"8.7","Tissue RNA - pancreas [nTPM]":"11.2","Tissue RNA - parathyroid gland [nTPM]":"15.0","Tissue RNA - pituitary gland [nTPM]":"15.5","Tissue RNA - placenta [nTPM]":"8.2","Tissue RNA - pons [nTPM]":"10.4","Tissue RNA - prostate [nTPM]":"7.4","Tissue RNA - rectum [nTPM]":"5.6","Tissue RNA - retina [nTPM]":"8.7","Tissue RNA - salivary gland [nTPM]":"12.5","Tissue RNA - seminal vesicle [nTPM]":"9.0","Tissue RNA - skeletal muscle [nTPM]":"3.6","Tissue RNA - skin 1 [nTPM]":"2.3","Tissue RNA - small intestine [nTPM]":"40.5","Tissue RNA - smooth muscle [nTPM]":"5.5","Tissue RNA - spinal cord [nTPM]":"9.8","Tissue RNA - spleen [nTPM]":"11.1","Tissue RNA - stomach 1 [nTPM]":"5.5","Tissue RNA - testis [nTPM]":"3.1","Tissue RNA - thalamus [nTPM]":"10.0","Tissue RNA - thymus [nTPM]":"23.4","Tissue RNA - thyroid gland [nTPM]":"6.4","Tissue RNA - tongue [nTPM]":"2.8","Tissue RNA - tonsil [nTPM]":"2.1","Tissue RNA - urinary bladder [nTPM]":"5.0","Tissue RNA - vagina [nTPM]":"2.6","Tissue RNA - white matter [nTPM]":"12.1","Cell RNA - A-431 [nTPM]":"5.4","Cell RNA - A549 [nTPM]":"22.5","Cell RNA - AF22 [nTPM]":"7.4","Cell RNA - AN3-CA [nTPM]":"12.2","Cell RNA - ASC diff [nTPM]":"5.9","Cell RNA - ASC TERT1 [nTPM]":"1.3","Cell RNA - BEWO [nTPM]":"22.9","Cell RNA - BJ [nTPM]":"6.3","Cell RNA - BJ hTERT+ [nTPM]":"4.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.7","Cell RNA - CACO-2 [nTPM]":"205.4","Cell RNA - CAPAN-2 [nTPM]":"6.4","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"3.6","Cell RNA - fHDF\/TERT166 [nTPM]":"3.4","Cell RNA - GAMG [nTPM]":"14.8","Cell RNA - HaCaT [nTPM]":"17.3","Cell RNA - HAP1 [nTPM]":"8.4","Cell RNA - HBEC3-KT [nTPM]":"14.1","Cell RNA - HBF TERT88 [nTPM]":"4.3","Cell RNA - HDLM-2 [nTPM]":"13.1","Cell RNA - HEK 293 [nTPM]":"19.6","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"14.0","Cell RNA - Hep G2 [nTPM]":"17.6","Cell RNA - HHSteC [nTPM]":"2.1","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"10.1","Cell RNA - HSkMC [nTPM]":"2.8","Cell RNA - hTCEpi [nTPM]":"25.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.3","Cell RNA - hTERT-HME1 [nTPM]":"15.8","Cell RNA - hTERT-RPE1 [nTPM]":"7.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.4","Cell RNA - JURKAT [nTPM]":"1.8","Cell RNA - K-562 [nTPM]":"8.9","Cell RNA - Karpas-707 [nTPM]":"1.2","Cell RNA - LHCN-M2 [nTPM]":"0.9","Cell RNA - MCF7 [nTPM]":"7.2","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"4.4","Cell RNA - OE19 [nTPM]":"5.2","Cell RNA - PC-3 [nTPM]":"2.9","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"6.0","Cell RNA - RPMI-8226 [nTPM]":"2.7","Cell RNA - RPTEC TERT1 [nTPM]":"4.0","Cell RNA - RT4 [nTPM]":"11.8","Cell RNA - SCLC-21H [nTPM]":"19.4","Cell RNA - SH-SY5Y [nTPM]":"10.2","Cell RNA - SiHa [nTPM]":"43.6","Cell RNA - SK-BR-3 [nTPM]":"20.1","Cell RNA - SK-MEL-30 [nTPM]":"2.4","Cell RNA - SuSa [nTPM]":"10.1","Cell RNA - T-47d [nTPM]":"15.6","Cell RNA - THP-1 [nTPM]":"3.4","Cell RNA - TIME [nTPM]":"0.6","Cell RNA - U-138 MG [nTPM]":"0.8","Cell RNA - U-2 OS [nTPM]":"8.6","Cell RNA - U-2197 [nTPM]":"1.2","Cell RNA - U-251 MG [nTPM]":"6.6","Cell RNA - U-266\/70 [nTPM]":"9.0","Cell RNA - U-266\/84 [nTPM]":"11.1","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"1.2","Cell RNA - U-937 [nTPM]":"1.3","Cell RNA - WM-115 [nTPM]":"4.7","Blood RNA - basophil [nTPM]":"5.2","Blood RNA - classical monocyte [nTPM]":"0.9","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"3.0","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"1.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"0.8","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.8","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"1.6","Blood RNA - non-classical monocyte [nTPM]":"2.6","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.9","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"8.1","Brain RNA - basal ganglia [nTPM]":"10.6","Brain RNA - cerebellum [nTPM]":"14.7","Brain RNA - cerebral cortex [nTPM]":"9.2","Brain RNA - hippocampal formation [nTPM]":"8.0","Brain RNA - hypothalamus [nTPM]":"8.4","Brain RNA - medulla oblongata [nTPM]":"11.2","Brain RNA - midbrain [nTPM]":"9.7","Brain RNA - pons [nTPM]":"10.4","Brain RNA - spinal cord [nTPM]":"9.8","Brain RNA - thalamus [nTPM]":"10.0","Brain RNA - white matter [nTPM]":"12.1","Single Cell Type RNA - Adipocytes [nTPM]":"1.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.3","Single Cell Type RNA - Astrocytes [nTPM]":"7.5","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"26.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"2.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.8","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.5","Single Cell Type RNA - Early spermatids [nTPM]":"3.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.8","Single Cell Type RNA - Endothelial cells [nTPM]":"1.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.7","Single Cell Type RNA - Fibroblasts [nTPM]":"3.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"4.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"27.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.7","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"21.5","Single Cell Type RNA - Langerhans cells [nTPM]":"1.0","Single Cell Type RNA - Late spermatids [nTPM]":"19.5","Single Cell Type RNA - Leydig cells [nTPM]":"4.1","Single Cell Type RNA - Macrophages [nTPM]":"8.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"2.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.8","Single Cell Type RNA - Paneth cells [nTPM]":"3.6","Single Cell Type RNA - Peritubular cells [nTPM]":"3.4","Single Cell Type RNA - Plasma cells [nTPM]":"3.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.4","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"5.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.3","Single Cell Type RNA - Urothelial cells [nTPM]":"1.6"},{"Gene":"SLC49A4","Gene synonym":["DIRC2","FLJ14784","RCC4"],"Ensembl":"ENSG00000138463","Gene description":"Solute carrier family 49 member 4","Uniprot":["Q96SL1"],"Chromosome":"3","Position":"122795069-122881139","Protein class":["Disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"44.0","Extravillous trophoblasts":"61.2","Syncytiotrophoblasts":"226.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072579"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA072579":"AB_2686536"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.53e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.48e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.81e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.81e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.13e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.4","Tissue RNA - adrenal gland [nTPM]":"5.0","Tissue RNA - amygdala [nTPM]":"4.9","Tissue RNA - appendix [nTPM]":"2.7","Tissue RNA - basal ganglia [nTPM]":"5.1","Tissue RNA - bone marrow [nTPM]":"5.9","Tissue RNA - breast [nTPM]":"3.1","Tissue RNA - cerebellum [nTPM]":"4.9","Tissue RNA - cerebral cortex [nTPM]":"5.3","Tissue RNA - cervix [nTPM]":"3.0","Tissue RNA - choroid plexus [nTPM]":"6.2","Tissue RNA - colon [nTPM]":"4.1","Tissue RNA - duodenum [nTPM]":"1.9","Tissue RNA - endometrium 1 [nTPM]":"2.6","Tissue RNA - epididymis [nTPM]":"3.8","Tissue RNA - esophagus [nTPM]":"5.6","Tissue RNA - fallopian tube [nTPM]":"3.1","Tissue RNA - gallbladder [nTPM]":"3.7","Tissue RNA - heart muscle [nTPM]":"6.4","Tissue RNA - hippocampal formation [nTPM]":"5.7","Tissue RNA - hypothalamus [nTPM]":"5.9","Tissue RNA - kidney [nTPM]":"4.6","Tissue RNA - liver [nTPM]":"3.5","Tissue RNA - lung [nTPM]":"5.2","Tissue RNA - lymph node [nTPM]":"2.0","Tissue RNA - medulla oblongata [nTPM]":"4.8","Tissue RNA - midbrain [nTPM]":"5.6","Tissue RNA - ovary [nTPM]":"2.2","Tissue RNA - pancreas [nTPM]":"6.5","Tissue RNA - parathyroid gland [nTPM]":"12.7","Tissue RNA - pituitary gland [nTPM]":"2.4","Tissue RNA - placenta [nTPM]":"7.6","Tissue RNA - pons [nTPM]":"5.6","Tissue RNA - prostate [nTPM]":"4.9","Tissue RNA - rectum [nTPM]":"4.5","Tissue RNA - retina [nTPM]":"5.7","Tissue RNA - salivary gland [nTPM]":"3.7","Tissue RNA - seminal vesicle [nTPM]":"3.6","Tissue RNA - skeletal muscle [nTPM]":"15.9","Tissue RNA - skin 1 [nTPM]":"6.6","Tissue RNA - small intestine [nTPM]":"2.6","Tissue RNA - smooth muscle [nTPM]":"2.7","Tissue RNA - spinal cord [nTPM]":"5.2","Tissue RNA - spleen [nTPM]":"2.8","Tissue RNA - stomach 1 [nTPM]":"3.1","Tissue RNA - testis [nTPM]":"2.5","Tissue RNA - thalamus [nTPM]":"5.6","Tissue RNA - thymus [nTPM]":"1.9","Tissue RNA - thyroid gland [nTPM]":"5.2","Tissue RNA - tongue [nTPM]":"14.0","Tissue RNA - tonsil [nTPM]":"2.5","Tissue RNA - urinary bladder [nTPM]":"4.0","Tissue RNA - vagina [nTPM]":"2.6","Tissue RNA - white matter [nTPM]":"5.9","Cell RNA - A-431 [nTPM]":"7.4","Cell RNA - A549 [nTPM]":"6.1","Cell RNA - AF22 [nTPM]":"5.9","Cell RNA - AN3-CA [nTPM]":"3.3","Cell RNA - ASC diff [nTPM]":"7.5","Cell RNA - ASC TERT1 [nTPM]":"6.1","Cell RNA - BEWO [nTPM]":"19.6","Cell RNA - BJ [nTPM]":"3.1","Cell RNA - BJ hTERT+ [nTPM]":"6.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.0","Cell RNA - CACO-2 [nTPM]":"14.4","Cell RNA - CAPAN-2 [nTPM]":"8.0","Cell RNA - Daudi [nTPM]":"1.0","Cell RNA - EFO-21 [nTPM]":"3.9","Cell RNA - fHDF\/TERT166 [nTPM]":"3.5","Cell RNA - GAMG [nTPM]":"10.9","Cell RNA - HaCaT [nTPM]":"10.5","Cell RNA - HAP1 [nTPM]":"4.3","Cell RNA - HBEC3-KT [nTPM]":"5.6","Cell RNA - HBF TERT88 [nTPM]":"4.7","Cell RNA - HDLM-2 [nTPM]":"1.6","Cell RNA - HEK 293 [nTPM]":"3.2","Cell RNA - HEL [nTPM]":"1.2","Cell RNA - HeLa [nTPM]":"3.3","Cell RNA - Hep G2 [nTPM]":"6.2","Cell RNA - HHSteC [nTPM]":"5.5","Cell RNA - HL-60 [nTPM]":"0.7","Cell RNA - HMC-1 [nTPM]":"0.7","Cell RNA - HSkMC [nTPM]":"5.0","Cell RNA - hTCEpi [nTPM]":"15.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.5","Cell RNA - hTERT-HME1 [nTPM]":"5.9","Cell RNA - hTERT-RPE1 [nTPM]":"7.6","Cell RNA - HUVEC TERT2 [nTPM]":"5.6","Cell RNA - JURKAT [nTPM]":"2.0","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"1.3","Cell RNA - LHCN-M2 [nTPM]":"6.3","Cell RNA - MCF7 [nTPM]":"3.3","Cell RNA - MOLT-4 [nTPM]":"0.9","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"5.3","Cell RNA - OE19 [nTPM]":"2.5","Cell RNA - PC-3 [nTPM]":"9.8","Cell RNA - REH [nTPM]":"2.0","Cell RNA - RH-30 [nTPM]":"13.3","Cell RNA - RPMI-8226 [nTPM]":"1.5","Cell RNA - RPTEC TERT1 [nTPM]":"7.0","Cell RNA - RT4 [nTPM]":"8.4","Cell RNA - SCLC-21H [nTPM]":"6.1","Cell RNA - SH-SY5Y [nTPM]":"4.6","Cell RNA - SiHa [nTPM]":"9.1","Cell RNA - SK-BR-3 [nTPM]":"4.1","Cell RNA - SK-MEL-30 [nTPM]":"8.4","Cell RNA - SuSa [nTPM]":"3.7","Cell RNA - T-47d [nTPM]":"4.8","Cell RNA - THP-1 [nTPM]":"1.6","Cell RNA - TIME [nTPM]":"8.0","Cell RNA - U-138 MG [nTPM]":"7.6","Cell RNA - U-2 OS [nTPM]":"2.8","Cell RNA - U-2197 [nTPM]":"4.6","Cell RNA - U-251 MG [nTPM]":"2.6","Cell RNA - U-266\/70 [nTPM]":"1.3","Cell RNA - U-266\/84 [nTPM]":"1.2","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"3.8","Cell RNA - U-937 [nTPM]":"1.3","Cell RNA - WM-115 [nTPM]":"4.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.9","Brain RNA - basal ganglia [nTPM]":"5.1","Brain RNA - cerebellum [nTPM]":"4.9","Brain RNA - cerebral cortex [nTPM]":"5.3","Brain RNA - hippocampal formation [nTPM]":"5.7","Brain RNA - hypothalamus [nTPM]":"5.9","Brain RNA - medulla oblongata [nTPM]":"4.8","Brain RNA - midbrain [nTPM]":"5.6","Brain RNA - pons [nTPM]":"5.6","Brain RNA - spinal cord [nTPM]":"5.2","Brain RNA - thalamus [nTPM]":"5.6","Brain RNA - white matter [nTPM]":"5.9","Single Cell Type RNA - Adipocytes [nTPM]":"3.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"44.0","Single Cell Type RNA - dendritic cells [nTPM]":"2.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"61.2","Single Cell Type RNA - Fibroblasts [nTPM]":"2.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"2.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"226.6","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SLC4A1","Gene synonym":["AE1","CD233","DI","EPB3","FR","RTA1A","SW","WD","WR"],"Ensembl":"ENSG00000004939","Gene description":"Solute carrier family 4 member 1 (Diego blood group)","Uniprot":["P02730"],"Chromosome":"17","Position":"44248390-44268141","Protein class":["Blood group antigen proteins","CD markers","Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Anion exchange","Ion transport","Transport"],"Molecular function":["Blood group antigen"],"Disease involvement":["Disease variant","Elliptocytosis","Hereditary hemolytic anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"bone marrow":"407.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"80","RNA single cell type specific nTPM":{"Erythroid cells":"1629.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"91","RNA cancer specific FPKM":{"renal cancer":"16.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"3.0","neutrophil":"2.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"K-562":"1.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015584","CAB034438","HPA063911"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"22000000","Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB034438":"AB_2123479","HPA015584":"AB_1844824","HPA063911":"AB_2685151"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.72e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"0.7","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"0.7","Tissue RNA - bone marrow [nTPM]":"407.2","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"2.2","Tissue RNA - cerebral cortex [nTPM]":"1.4","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"1.7","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.9","Tissue RNA - hippocampal formation [nTPM]":"0.6","Tissue RNA - hypothalamus [nTPM]":"0.5","Tissue RNA - kidney [nTPM]":"72.1","Tissue RNA - liver [nTPM]":"2.2","Tissue RNA - lung [nTPM]":"1.8","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"0.8","Tissue RNA - midbrain [nTPM]":"0.6","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.6","Tissue RNA - placenta [nTPM]":"10.9","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.7","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"2.2","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"12.8","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"1.1","Tissue RNA - thymus [nTPM]":"0.7","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"1.5","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"1.7","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.6","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"0.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"1.4","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.6","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.6","Cell RNA - THP-1 [nTPM]":"0.6","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"0.5","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"3.0","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"2.7","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"0.7","Brain RNA - basal ganglia [nTPM]":"0.7","Brain RNA - cerebellum [nTPM]":"2.2","Brain RNA - cerebral cortex [nTPM]":"1.4","Brain RNA - hippocampal formation [nTPM]":"0.6","Brain RNA - hypothalamus [nTPM]":"0.5","Brain RNA - medulla oblongata [nTPM]":"0.8","Brain RNA - midbrain [nTPM]":"0.6","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"1.1","Brain RNA - white matter [nTPM]":"1.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"2.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1629.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.6","Single Cell Type RNA - Fibroblasts [nTPM]":"0.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"1.5","Single Cell Type RNA - Theca cells [nTPM]":"0.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"SLC4A11","Gene synonym":["BTR1","CDPD1","CHED2","dJ794I6.2","FECD4","NaBC1"],"Ensembl":"ENSG00000088836","Gene description":"Solute carrier family 4 member 11","Uniprot":["Q8NBS3"],"Chromosome":"20","Position":"3227417-3239559","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Anion exchange","Ion transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Corneal dystrophy","Deafness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"51.3","salivary gland":"54.0","thyroid gland":"60.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Club cells":"25.5","Collecting duct cells":"112.2","Ionocytes":"79.3","Respiratory ciliated cells":"48.1","Sertoli cells":"26.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"70.6","Hep G2":"43.0","RT4":"30.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018120","HPA058377"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA018120":"AB_1857186","HPA058377":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.03e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.66e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.21e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-3"},"Tissue RNA - adipose tissue [nTPM]":"2.4","Tissue RNA - adrenal gland [nTPM]":"6.9","Tissue RNA - amygdala [nTPM]":"4.5","Tissue RNA - appendix [nTPM]":"0.7","Tissue RNA - basal ganglia [nTPM]":"3.5","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"3.4","Tissue RNA - cerebellum [nTPM]":"2.3","Tissue RNA - cerebral cortex [nTPM]":"3.1","Tissue RNA - cervix [nTPM]":"10.9","Tissue RNA - choroid plexus [nTPM]":"5.6","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.5","Tissue RNA - epididymis [nTPM]":"2.6","Tissue RNA - esophagus [nTPM]":"16.5","Tissue RNA - fallopian tube [nTPM]":"1.7","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"0.8","Tissue RNA - hippocampal formation [nTPM]":"2.9","Tissue RNA - hypothalamus [nTPM]":"1.4","Tissue RNA - kidney [nTPM]":"51.3","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"2.0","Tissue RNA - lymph node [nTPM]":"1.4","Tissue RNA - medulla oblongata [nTPM]":"2.0","Tissue RNA - midbrain [nTPM]":"2.3","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.5","Tissue RNA - parathyroid gland [nTPM]":"0.6","Tissue RNA - pituitary gland [nTPM]":"4.3","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"2.6","Tissue RNA - prostate [nTPM]":"5.4","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"54.0","Tissue RNA - seminal vesicle [nTPM]":"7.0","Tissue RNA - skeletal muscle [nTPM]":"5.2","Tissue RNA - skin 1 [nTPM]":"12.8","Tissue RNA - small intestine [nTPM]":"0.6","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"0.7","Tissue RNA - stomach 1 [nTPM]":"2.5","Tissue RNA - testis [nTPM]":"5.9","Tissue RNA - thalamus [nTPM]":"4.3","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"60.9","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"1.8","Tissue RNA - urinary bladder [nTPM]":"3.4","Tissue RNA - vagina [nTPM]":"5.8","Tissue RNA - white matter [nTPM]":"1.9","Cell RNA - A-431 [nTPM]":"11.0","Cell RNA - A549 [nTPM]":"15.5","Cell RNA - AF22 [nTPM]":"1.8","Cell RNA - AN3-CA [nTPM]":"7.9","Cell RNA - ASC diff [nTPM]":"5.1","Cell RNA - ASC TERT1 [nTPM]":"1.3","Cell RNA - BEWO [nTPM]":"21.1","Cell RNA - BJ [nTPM]":"5.4","Cell RNA - BJ hTERT+ [nTPM]":"3.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.6","Cell RNA - CACO-2 [nTPM]":"1.1","Cell RNA - CAPAN-2 [nTPM]":"14.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"6.1","Cell RNA - fHDF\/TERT166 [nTPM]":"1.9","Cell RNA - GAMG [nTPM]":"6.6","Cell RNA - HaCaT [nTPM]":"70.6","Cell RNA - HAP1 [nTPM]":"8.3","Cell RNA - HBEC3-KT [nTPM]":"16.8","Cell RNA - HBF TERT88 [nTPM]":"0.5","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"3.2","Cell RNA - HEL [nTPM]":"0.7","Cell RNA - HeLa [nTPM]":"7.5","Cell RNA - Hep G2 [nTPM]":"43.0","Cell RNA - HHSteC [nTPM]":"3.2","Cell RNA - HL-60 [nTPM]":"4.0","Cell RNA - HMC-1 [nTPM]":"13.6","Cell RNA - HSkMC [nTPM]":"0.7","Cell RNA - hTCEpi [nTPM]":"6.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.4","Cell RNA - hTERT-HME1 [nTPM]":"3.2","Cell RNA - hTERT-RPE1 [nTPM]":"2.3","Cell RNA - HUVEC TERT2 [nTPM]":"7.0","Cell RNA - JURKAT [nTPM]":"9.8","Cell RNA - K-562 [nTPM]":"1.6","Cell RNA - Karpas-707 [nTPM]":"9.7","Cell RNA - LHCN-M2 [nTPM]":"2.9","Cell RNA - MCF7 [nTPM]":"7.2","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"12.1","Cell RNA - OE19 [nTPM]":"13.6","Cell RNA - PC-3 [nTPM]":"20.7","Cell RNA - REH [nTPM]":"2.6","Cell RNA - RH-30 [nTPM]":"10.3","Cell RNA - RPMI-8226 [nTPM]":"3.5","Cell RNA - RPTEC TERT1 [nTPM]":"16.9","Cell RNA - RT4 [nTPM]":"30.7","Cell RNA - SCLC-21H [nTPM]":"0.9","Cell RNA - SH-SY5Y [nTPM]":"4.9","Cell RNA - SiHa [nTPM]":"2.7","Cell RNA - SK-BR-3 [nTPM]":"17.5","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"5.4","Cell RNA - T-47d [nTPM]":"6.7","Cell RNA - THP-1 [nTPM]":"7.0","Cell RNA - TIME [nTPM]":"12.1","Cell RNA - U-138 MG [nTPM]":"2.1","Cell RNA - U-2 OS [nTPM]":"7.0","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"2.7","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"2.8","Cell RNA - WM-115 [nTPM]":"0.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.5","Brain RNA - basal ganglia [nTPM]":"3.5","Brain RNA - cerebellum [nTPM]":"2.3","Brain RNA - cerebral cortex [nTPM]":"3.1","Brain RNA - hippocampal formation [nTPM]":"2.9","Brain RNA - hypothalamus [nTPM]":"1.4","Brain RNA - medulla oblongata [nTPM]":"2.0","Brain RNA - midbrain [nTPM]":"2.3","Brain RNA - pons [nTPM]":"2.6","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"4.3","Brain RNA - white matter [nTPM]":"1.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"25.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"112.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.7","Single Cell Type RNA - Early spermatids [nTPM]":"5.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"79.3","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.0","Single Cell Type RNA - Paneth cells [nTPM]":"1.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"48.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.8","Single Cell Type RNA - Spermatocytes [nTPM]":"3.0","Single Cell Type RNA - Spermatogonia [nTPM]":"4.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"5.7"},{"Gene":"SLC4A4","Gene synonym":["hhNMC","HNBC1","NBC1","NBC2","pNBC","SLC4A5"],"Ensembl":"ENSG00000080493","Gene description":"Solute carrier family 4 member 4","Uniprot":["Q9Y6R1"],"Chromosome":"4","Position":"71062667-71572087","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"119.5","pancreas":"260.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"819.1","Cholangiocytes":"133.0","Distal enterocytes":"282.9","Ductal cells":"129.2","Proximal tubular cells":"211.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"23.9","pancreatic cancer":"22.5","prostate cancer":"47.4","renal cancer":"19.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ":"13.0","fHDF\/TERT166":"6.1","HBF TERT88":"5.7","hTERT-RPE1":"6.0","RPTEC TERT1":"15.4","U-138 MG":"7.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022493","HPA035628","HPA035629","HPA079220"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022493":null,"HPA035628":"AB_2674708","HPA035629":"AB_2674709","HPA079220":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.69e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.18e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.1","Tissue RNA - adrenal gland [nTPM]":"0.7","Tissue RNA - amygdala [nTPM]":"30.0","Tissue RNA - appendix [nTPM]":"2.2","Tissue RNA - basal ganglia [nTPM]":"43.6","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"1.0","Tissue RNA - cerebellum [nTPM]":"47.0","Tissue RNA - cerebral cortex [nTPM]":"32.5","Tissue RNA - cervix [nTPM]":"11.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"41.1","Tissue RNA - duodenum [nTPM]":"54.3","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"1.2","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"29.4","Tissue RNA - heart muscle [nTPM]":"6.2","Tissue RNA - hippocampal formation [nTPM]":"21.5","Tissue RNA - hypothalamus [nTPM]":"37.9","Tissue RNA - kidney [nTPM]":"119.5","Tissue RNA - liver [nTPM]":"21.7","Tissue RNA - lung [nTPM]":"6.9","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"38.6","Tissue RNA - midbrain [nTPM]":"28.0","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"260.3","Tissue RNA - parathyroid gland [nTPM]":"17.2","Tissue RNA - pituitary gland [nTPM]":"5.8","Tissue RNA - placenta [nTPM]":"2.7","Tissue RNA - pons [nTPM]":"24.8","Tissue RNA - prostate [nTPM]":"34.7","Tissue RNA - rectum [nTPM]":"41.2","Tissue RNA - retina [nTPM]":"5.1","Tissue RNA - salivary gland [nTPM]":"2.5","Tissue RNA - seminal vesicle [nTPM]":"1.1","Tissue RNA - skeletal muscle [nTPM]":"2.2","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"14.6","Tissue RNA - smooth muscle [nTPM]":"1.7","Tissue RNA - spinal cord [nTPM]":"38.2","Tissue RNA - spleen [nTPM]":"0.8","Tissue RNA - stomach 1 [nTPM]":"18.6","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"38.5","Tissue RNA - thymus [nTPM]":"3.5","Tissue RNA - thyroid gland [nTPM]":"22.0","Tissue RNA - tongue [nTPM]":"3.5","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"4.5","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"33.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"3.5","Cell RNA - AF22 [nTPM]":"1.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"13.0","Cell RNA - BJ hTERT+ [nTPM]":"1.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.6","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"6.1","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"5.7","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.7","Cell RNA - HEL [nTPM]":"0.9","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"6.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"1.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"4.8","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.9","Cell RNA - RPTEC TERT1 [nTPM]":"15.4","Cell RNA - RT4 [nTPM]":"4.1","Cell RNA - SCLC-21H [nTPM]":"0.9","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"1.3","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"7.7","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"5.5","Cell RNA - U-251 MG [nTPM]":"0.6","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"5.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"30.0","Brain RNA - basal ganglia [nTPM]":"43.6","Brain RNA - cerebellum [nTPM]":"47.0","Brain RNA - cerebral cortex [nTPM]":"32.5","Brain RNA - hippocampal formation [nTPM]":"21.5","Brain RNA - hypothalamus [nTPM]":"37.9","Brain RNA - medulla oblongata [nTPM]":"38.6","Brain RNA - midbrain [nTPM]":"28.0","Brain RNA - pons [nTPM]":"24.8","Brain RNA - spinal cord [nTPM]":"38.2","Brain RNA - thalamus [nTPM]":"38.5","Brain RNA - white matter [nTPM]":"33.2","Single Cell Type RNA - Adipocytes [nTPM]":"1.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"37.1","Single Cell Type RNA - Astrocytes [nTPM]":"819.1","Single Cell Type RNA - B-cells [nTPM]":"2.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"3.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"24.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"133.0","Single Cell Type RNA - Club cells [nTPM]":"31.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"7.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"282.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"129.2","Single Cell Type RNA - Early spermatids [nTPM]":"11.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"1.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.5","Single Cell Type RNA - Erythroid cells [nTPM]":"4.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"51.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"24.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"4.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"33.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.8","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"35.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"93.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"65.6","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.2","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"2.3","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"34.7","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"3.9","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"29.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.2","Single Cell Type RNA - Paneth cells [nTPM]":"60.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"40.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"31.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"211.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"6.8","Single Cell Type RNA - Theca cells [nTPM]":"2.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"68.1","Single Cell Type RNA - Urothelial cells [nTPM]":"12.3"},{"Gene":"SLC52A3","Gene synonym":["bA371L19.1","C20orf54","hRFT2","RFVT3"],"Ensembl":"ENSG00000101276","Gene description":"Solute carrier family 52 member 3","Uniprot":["Q9NQ40"],"Chromosome":"20","Position":"760080-776015","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"19.2","testis":"40.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"23.9","Cytotrophoblasts":"32.8","Distal enterocytes":"18.8","Glandular and luminal cells":"21.3","Paneth cells":"21.7","Proximal enterocytes":"35.5","Syncytiotrophoblasts":"52.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"2.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"2.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"42.1","OE19":"31.8","RT4":"12.3","SK-BR-3":"15.4","T-47d":"20.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049391","HPA059078"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049391":"AB_2680743","HPA059078":"AB_2732630"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.03e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.51e-6"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Tissue RNA - adipose tissue [nTPM]":"2.1","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"11.0","Tissue RNA - appendix [nTPM]":"1.5","Tissue RNA - basal ganglia [nTPM]":"8.9","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"2.6","Tissue RNA - cerebellum [nTPM]":"9.5","Tissue RNA - cerebral cortex [nTPM]":"11.4","Tissue RNA - cervix [nTPM]":"2.3","Tissue RNA - choroid plexus [nTPM]":"5.5","Tissue RNA - colon [nTPM]":"11.5","Tissue RNA - duodenum [nTPM]":"14.4","Tissue RNA - endometrium 1 [nTPM]":"2.0","Tissue RNA - epididymis [nTPM]":"2.0","Tissue RNA - esophagus [nTPM]":"4.9","Tissue RNA - fallopian tube [nTPM]":"1.8","Tissue RNA - gallbladder [nTPM]":"2.6","Tissue RNA - heart muscle [nTPM]":"5.7","Tissue RNA - hippocampal formation [nTPM]":"9.0","Tissue RNA - hypothalamus [nTPM]":"11.1","Tissue RNA - kidney [nTPM]":"9.4","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"1.2","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"12.9","Tissue RNA - midbrain [nTPM]":"9.8","Tissue RNA - ovary [nTPM]":"0.9","Tissue RNA - pancreas [nTPM]":"1.6","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"4.3","Tissue RNA - pons [nTPM]":"12.3","Tissue RNA - prostate [nTPM]":"8.0","Tissue RNA - rectum [nTPM]":"7.1","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"6.1","Tissue RNA - seminal vesicle [nTPM]":"4.0","Tissue RNA - skeletal muscle [nTPM]":"0.6","Tissue RNA - skin 1 [nTPM]":"1.8","Tissue RNA - small intestine [nTPM]":"19.2","Tissue RNA - smooth muscle [nTPM]":"1.7","Tissue RNA - spinal cord [nTPM]":"9.8","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"5.6","Tissue RNA - testis [nTPM]":"40.1","Tissue RNA - thalamus [nTPM]":"12.5","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.5","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"0.8","Tissue RNA - urinary bladder [nTPM]":"4.9","Tissue RNA - vagina [nTPM]":"2.5","Tissue RNA - white matter [nTPM]":"9.7","Cell RNA - A-431 [nTPM]":"6.6","Cell RNA - A549 [nTPM]":"2.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"3.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"4.6","Cell RNA - CAPAN-2 [nTPM]":"42.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"7.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"6.9","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"6.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.8","Cell RNA - HeLa [nTPM]":"0.7","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"1.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"31.8","Cell RNA - PC-3 [nTPM]":"4.5","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"12.3","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"7.2","Cell RNA - SK-BR-3 [nTPM]":"15.4","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.8","Cell RNA - T-47d [nTPM]":"20.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"2.1","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"11.0","Brain RNA - basal ganglia [nTPM]":"8.9","Brain RNA - cerebellum [nTPM]":"9.5","Brain RNA - cerebral cortex [nTPM]":"11.4","Brain RNA - hippocampal formation [nTPM]":"9.0","Brain RNA - hypothalamus [nTPM]":"11.1","Brain RNA - medulla oblongata [nTPM]":"12.9","Brain RNA - midbrain [nTPM]":"9.8","Brain RNA - pons [nTPM]":"12.3","Brain RNA - spinal cord [nTPM]":"9.8","Brain RNA - thalamus [nTPM]":"12.5","Brain RNA - white matter [nTPM]":"9.7","Single Cell Type RNA - Adipocytes [nTPM]":"3.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"5.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"32.8","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.6","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.1","Single Cell Type RNA - Endothelial cells [nTPM]":"10.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.9","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"5.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.3","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.2","Single Cell Type RNA - Paneth cells [nTPM]":"21.7","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"35.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"52.1","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"1.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.8","Single Cell Type RNA - Urothelial cells [nTPM]":"5.8"},{"Gene":"SLC5A1","Gene synonym":["D22S675","NAGT","SGLT1"],"Ensembl":"ENSG00000100170","Gene description":"Solute carrier family 5 member 1","Uniprot":["P13866"],"Chromosome":"22","Position":"32043261-32113029","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Sugar transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"intestine":"528.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Proximal enterocytes":"768.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"20.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"13","RNA cell line specific nTPM":{"OE19":"34.2"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"26","RNA mouse brain regional specific nTPM":{"cerebellum":"7.6"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015467","HPA051805","HPA055106"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":["Nuclear membrane","Cytosol"],"Antibody RRID":{"CAB015467":null,"HPA051805":"AB_2681618","HPA055106":"AB_2682695"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.59e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.97e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"4.2","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"9.7","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"12.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"10.7","Tissue RNA - duodenum [nTPM]":"528.1","Tissue RNA - endometrium 1 [nTPM]":"0.5","Tissue RNA - epididymis [nTPM]":"3.5","Tissue RNA - esophagus [nTPM]":"5.1","Tissue RNA - fallopian tube [nTPM]":"1.1","Tissue RNA - gallbladder [nTPM]":"26.9","Tissue RNA - heart muscle [nTPM]":"75.2","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"6.6","Tissue RNA - liver [nTPM]":"1.7","Tissue RNA - lung [nTPM]":"2.1","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"1.6","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"1.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"3.0","Tissue RNA - rectum [nTPM]":"9.7","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"19.0","Tissue RNA - seminal vesicle [nTPM]":"2.4","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"13.5","Tissue RNA - small intestine [nTPM]":"302.4","Tissue RNA - smooth muscle [nTPM]":"0.7","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"2.9","Tissue RNA - stomach 1 [nTPM]":"7.2","Tissue RNA - testis [nTPM]":"2.3","Tissue RNA - thalamus [nTPM]":"0.5","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"4.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"6.2","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.6","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"2.6","Cell RNA - CAPAN-2 [nTPM]":"0.5","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"1.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"34.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"2.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"1.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.5","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"115.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"115.8","Single Cell Type RNA - Club cells [nTPM]":"8.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"19.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.0","Single Cell Type RNA - Early spermatids [nTPM]":"38.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.4","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"25.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"34.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"71.3","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.9","Single Cell Type RNA - Paneth cells [nTPM]":"32.6","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"768.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"10.1","Single Cell Type RNA - Spermatogonia [nTPM]":"4.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"41.2","Single Cell Type RNA - Urothelial cells [nTPM]":"6.7"},{"Gene":"SLC5A7","Gene synonym":["CHT1","hCHT"],"Ensembl":"ENSG00000115665","Gene description":"Solute carrier family 5 member 7","Uniprot":["Q9GZV3"],"Chromosome":"2","Position":"107986523-108013994","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Neurotransmitter biosynthesis","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Congenital myasthenic syndrome","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"brain":"32.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"3.2","Club cells":"3.1","Respiratory ciliated cells":"1.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"0.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"20","RNA cell line specific nTPM":{"RT4":"3.6","SCLC-21H":"1.0"},"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"basal ganglia":"23.1","hypothalamus":"9.0","midbrain":"9.4","pons and medulla":"14.4","thalamus":"6.2"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"basal ganglia":"20.4","pons":"26.5","spinal cord":"46.7"},"Antibody":["HPA046105"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies","Cell Junctions","Intermediate filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Subcellular main location":["Cell Junctions","Intermediate filaments"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA046105":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.7","Tissue RNA - amygdala [nTPM]":"1.1","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"3.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"10.3","Tissue RNA - cervix [nTPM]":"0.7","Tissue RNA - choroid plexus [nTPM]":"1.0","Tissue RNA - colon [nTPM]":"2.6","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"5.3","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"20.2","Tissue RNA - midbrain [nTPM]":"21.2","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"32.9","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"0.9","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"1.1","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.8","Tissue RNA - smooth muscle [nTPM]":"0.7","Tissue RNA - spinal cord [nTPM]":"2.8","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"1.6","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"1.2","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"1.3","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"7.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"3.6","Cell RNA - SCLC-21H [nTPM]":"1.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.1","Brain RNA - basal ganglia [nTPM]":"3.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"10.3","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"5.3","Brain RNA - medulla oblongata [nTPM]":"20.2","Brain RNA - midbrain [nTPM]":"21.2","Brain RNA - pons [nTPM]":"32.9","Brain RNA - spinal cord [nTPM]":"2.8","Brain RNA - thalamus [nTPM]":"1.6","Brain RNA - white matter [nTPM]":"7.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"SLC6A14","Gene synonym":[],"Ensembl":"ENSG00000268104","Gene description":"Solute carrier family 6 member 14","Uniprot":["Q9UN76"],"Chromosome":"X","Position":"116436606-116461458","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"16.0","salivary gland":"20.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Alveolar cells type 2":"115.7","Basal respiratory cells":"94.9","Club cells":"225.6","Pancreatic endocrine cells":"170.4","Respiratory ciliated cells":"58.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"1.7","Hep G2":"3.4","OE19":"1.2"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003193"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA003193":"AB_2190122"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.74e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"2.2","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"7.7","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"7.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.4","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"2.3","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"16.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"1.0","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"20.6","Tissue RNA - seminal vesicle [nTPM]":"1.3","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"3.2","Tissue RNA - small intestine [nTPM]":"0.6","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"3.8","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"1.1","Tissue RNA - urinary bladder [nTPM]":"1.6","Tissue RNA - vagina [nTPM]":"5.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"1.7","Cell RNA - Hep G2 [nTPM]":"3.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"1.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"115.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"94.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"225.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"17.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"32.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"170.4","Single Cell Type RNA - Paneth cells [nTPM]":"10.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"58.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.9","Single Cell Type RNA - Urothelial cells [nTPM]":"23.4"},{"Gene":"SLC6A17","Gene synonym":[],"Ensembl":"ENSG00000197106","Gene description":"Solute carrier family 6 member 17","Uniprot":["Q9H1V8"],"Chromosome":"1","Position":"110150494-110202202","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Neurotransmitter transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"52.9","pituitary gland":"25.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Excitatory neurons":"60.6","Inhibitory neurons":"59.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"melanoma":"17.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"SK-MEL-30":"36.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008043","HPA008044"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA008043":null,"HPA008044":"AB_1857192"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"5.9","Tissue RNA - amygdala [nTPM]":"21.6","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"26.3","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"1.2","Tissue RNA - cerebral cortex [nTPM]":"52.9","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"20.1","Tissue RNA - hypothalamus [nTPM]":"9.6","Tissue RNA - kidney [nTPM]":"1.3","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"13.7","Tissue RNA - midbrain [nTPM]":"8.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"1.4","Tissue RNA - parathyroid gland [nTPM]":"8.8","Tissue RNA - pituitary gland [nTPM]":"25.3","Tissue RNA - placenta [nTPM]":"0.8","Tissue RNA - pons [nTPM]":"10.5","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"6.0","Tissue RNA - salivary gland [nTPM]":"0.6","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"6.2","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.7","Tissue RNA - testis [nTPM]":"1.8","Tissue RNA - thalamus [nTPM]":"24.8","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"15.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"1.5","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"5.5","Cell RNA - BJ hTERT+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"1.9","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"1.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"2.9","Cell RNA - SH-SY5Y [nTPM]":"0.8","Cell RNA - SiHa [nTPM]":"6.2","Cell RNA - SK-BR-3 [nTPM]":"1.9","Cell RNA - SK-MEL-30 [nTPM]":"36.0","Cell RNA - SuSa [nTPM]":"1.0","Cell RNA - T-47d [nTPM]":"0.9","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.6","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"7.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"3.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"21.6","Brain RNA - basal ganglia [nTPM]":"26.3","Brain RNA - cerebellum [nTPM]":"1.2","Brain RNA - cerebral cortex [nTPM]":"52.9","Brain RNA - hippocampal formation [nTPM]":"20.1","Brain RNA - hypothalamus [nTPM]":"9.6","Brain RNA - medulla oblongata [nTPM]":"13.7","Brain RNA - midbrain [nTPM]":"8.2","Brain RNA - pons [nTPM]":"10.5","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"24.8","Brain RNA - white matter [nTPM]":"15.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"5.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"60.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"59.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"1.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SLC6A18","Gene synonym":["FLJ31236","Xtrp2"],"Ensembl":"ENSG00000164363","Gene description":"Solute carrier family 6 member 18","Uniprot":["Q96N87"],"Chromosome":"5","Position":"1225381-1246189","Protein class":["Disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Neurotransmitter transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"76","RNA tissue specific nTPM":{"kidney":"8.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Proximal tubular cells":"55.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"44","RNA cancer specific FPKM":{"renal cancer":"4.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011885"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA011885":"AB_1857198"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"8.2","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"55.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SLC6A19","Gene synonym":[],"Ensembl":"ENSG00000174358","Gene description":"Solute carrier family 6 member 19","Uniprot":["Q695T7"],"Chromosome":"5","Position":"1201595-1225111","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"35","RNA tissue specific nTPM":{"intestine":"142.4","kidney":"88.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Proximal enterocytes":"561.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"renal cancer":"7.9","stomach cancer":"5.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"BEWO":"14.3","HEL":"18.3","OE19":"5.0"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037415","HPA043207"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA037415":"AB_10672346","HPA043207":"AB_2678363"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.14e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"5.1","Tissue RNA - duodenum [nTPM]":"139.7","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"3.3","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"88.7","Tissue RNA - liver [nTPM]":"0.9","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.7","Tissue RNA - rectum [nTPM]":"5.6","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"142.4","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"1.3","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"14.3","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"18.3","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"2.7","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"5.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.9","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.3","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"64.3","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"104.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.6","Single Cell Type RNA - Fibroblasts [nTPM]":"1.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"28.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"561.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"76.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.7","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SLC6A20","Gene synonym":["IMINO","SIT1","XT3","Xtrp3"],"Ensembl":"ENSG00000163817","Gene description":"Solute carrier family 6 member 20","Uniprot":["Q9NP91"],"Chromosome":"3","Position":"45755449-45796536","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"choroid plexus":"59.2","intestine":"24.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Proximal enterocytes":"74.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"4.7"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"1.7","OE19":"3.9","SuSa":"1.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.55e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"0.7","Tissue RNA - basal ganglia [nTPM]":"1.7","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"1.8","Tissue RNA - cerebral cortex [nTPM]":"4.7","Tissue RNA - cervix [nTPM]":"1.3","Tissue RNA - choroid plexus [nTPM]":"59.2","Tissue RNA - colon [nTPM]":"0.5","Tissue RNA - duodenum [nTPM]":"24.2","Tissue RNA - endometrium 1 [nTPM]":"0.8","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"6.9","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"2.0","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"1.9","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"1.9","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"3.0","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"1.3","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"0.7","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.8","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"17.6","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"5.2","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"0.7","Tissue RNA - thymus [nTPM]":"0.9","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.5","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.9","Cell RNA - CAPAN-2 [nTPM]":"0.7","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"1.7","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.7","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"3.9","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.8","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.1","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"1.7","Brain RNA - cerebellum [nTPM]":"1.8","Brain RNA - cerebral cortex [nTPM]":"4.7","Brain RNA - hippocampal formation [nTPM]":"2.0","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"0.7","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"2.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"13.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.4","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"74.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.0","Single Cell Type RNA - Urothelial cells [nTPM]":"4.2"},{"Gene":"SLC6A5","Gene synonym":["GLYT2","NET1"],"Ensembl":"ENSG00000165970","Gene description":"Solute carrier family 6 member 5","Uniprot":["Q9Y345"],"Chromosome":"11","Position":"20599594-20659285","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Neurotransmitter transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"23","RNA tissue specific nTPM":{"brain":"22.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"39","RNA single cell type specific nTPM":{"Early spermatids":"20.6","Late spermatids":"66.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"medulla oblongata":"22.2","pons":"20.0","spinal cord":"7.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"9","RNA mouse brain regional specific nTPM":{"pons and medulla":"49.3"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"8","RNA pig brain regional specific nTPM":{"medulla oblongata":"30.5","spinal cord":"18.3"},"Antibody":["CAB079052"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB079052":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"1.2","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"1.3","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.9","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"22.2","Tissue RNA - midbrain [nTPM]":"1.3","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.6","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"20.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"7.6","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"3.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.2","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"1.3","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"22.2","Brain RNA - midbrain [nTPM]":"1.3","Brain RNA - pons [nTPM]":"20.0","Brain RNA - spinal cord [nTPM]":"7.6","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"3.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"20.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"66.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SLC6A6","Gene synonym":["TAUT"],"Ensembl":"ENSG00000131389","Gene description":"Solute carrier family 6 member 6","Uniprot":["P31641"],"Chromosome":"3","Position":"14402576-14489349","Protein class":["Disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Neurotransmitter transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"68.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"571.3","Rod photoreceptor cells":"547.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"neutrophil":"59.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"59.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"66.6","RPTEC TERT1":"111.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015028","HPA016488"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cell Junctions","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Cell Junctions","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA015028":"AB_1857200","HPA016488":"AB_1857202"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.22e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.75e-8"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.78e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.9","Tissue RNA - adrenal gland [nTPM]":"25.6","Tissue RNA - amygdala [nTPM]":"1.7","Tissue RNA - appendix [nTPM]":"8.4","Tissue RNA - basal ganglia [nTPM]":"6.9","Tissue RNA - bone marrow [nTPM]":"54.7","Tissue RNA - breast [nTPM]":"8.5","Tissue RNA - cerebellum [nTPM]":"5.0","Tissue RNA - cerebral cortex [nTPM]":"7.7","Tissue RNA - cervix [nTPM]":"11.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"3.9","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"10.4","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"6.7","Tissue RNA - fallopian tube [nTPM]":"6.7","Tissue RNA - gallbladder [nTPM]":"9.4","Tissue RNA - heart muscle [nTPM]":"24.4","Tissue RNA - hippocampal formation [nTPM]":"3.5","Tissue RNA - hypothalamus [nTPM]":"3.8","Tissue RNA - kidney [nTPM]":"12.2","Tissue RNA - liver [nTPM]":"1.5","Tissue RNA - lung [nTPM]":"20.5","Tissue RNA - lymph node [nTPM]":"7.5","Tissue RNA - medulla oblongata [nTPM]":"9.6","Tissue RNA - midbrain [nTPM]":"6.6","Tissue RNA - ovary [nTPM]":"28.9","Tissue RNA - pancreas [nTPM]":"2.3","Tissue RNA - parathyroid gland [nTPM]":"2.5","Tissue RNA - pituitary gland [nTPM]":"7.4","Tissue RNA - placenta [nTPM]":"7.9","Tissue RNA - pons [nTPM]":"6.7","Tissue RNA - prostate [nTPM]":"4.3","Tissue RNA - rectum [nTPM]":"2.4","Tissue RNA - retina [nTPM]":"68.5","Tissue RNA - salivary gland [nTPM]":"17.1","Tissue RNA - seminal vesicle [nTPM]":"7.2","Tissue RNA - skeletal muscle [nTPM]":"30.9","Tissue RNA - skin 1 [nTPM]":"18.3","Tissue RNA - small intestine [nTPM]":"17.1","Tissue RNA - smooth muscle [nTPM]":"6.9","Tissue RNA - spinal cord [nTPM]":"1.7","Tissue RNA - spleen [nTPM]":"15.6","Tissue RNA - stomach 1 [nTPM]":"9.4","Tissue RNA - testis [nTPM]":"3.7","Tissue RNA - thalamus [nTPM]":"11.0","Tissue RNA - thymus [nTPM]":"4.5","Tissue RNA - thyroid gland [nTPM]":"9.3","Tissue RNA - tongue [nTPM]":"8.7","Tissue RNA - tonsil [nTPM]":"9.1","Tissue RNA - urinary bladder [nTPM]":"8.1","Tissue RNA - vagina [nTPM]":"6.1","Tissue RNA - white matter [nTPM]":"6.8","Cell RNA - A-431 [nTPM]":"4.1","Cell RNA - A549 [nTPM]":"18.4","Cell RNA - AF22 [nTPM]":"4.6","Cell RNA - AN3-CA [nTPM]":"10.1","Cell RNA - ASC diff [nTPM]":"11.6","Cell RNA - ASC TERT1 [nTPM]":"5.7","Cell RNA - BEWO [nTPM]":"15.9","Cell RNA - BJ [nTPM]":"4.3","Cell RNA - BJ hTERT+ [nTPM]":"26.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.2","Cell RNA - CACO-2 [nTPM]":"8.8","Cell RNA - CAPAN-2 [nTPM]":"5.6","Cell RNA - Daudi [nTPM]":"12.6","Cell RNA - EFO-21 [nTPM]":"4.5","Cell RNA - fHDF\/TERT166 [nTPM]":"10.9","Cell RNA - GAMG [nTPM]":"11.7","Cell RNA - HaCaT [nTPM]":"4.3","Cell RNA - HAP1 [nTPM]":"4.5","Cell RNA - HBEC3-KT [nTPM]":"10.1","Cell RNA - HBF TERT88 [nTPM]":"16.5","Cell RNA - HDLM-2 [nTPM]":"3.7","Cell RNA - HEK 293 [nTPM]":"9.7","Cell RNA - HEL [nTPM]":"8.8","Cell RNA - HeLa [nTPM]":"66.6","Cell RNA - Hep G2 [nTPM]":"24.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"3.7","Cell RNA - HMC-1 [nTPM]":"22.3","Cell RNA - HSkMC [nTPM]":"1.9","Cell RNA - hTCEpi [nTPM]":"2.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.8","Cell RNA - hTERT-HME1 [nTPM]":"1.6","Cell RNA - hTERT-RPE1 [nTPM]":"7.7","Cell RNA - HUVEC TERT2 [nTPM]":"14.5","Cell RNA - JURKAT [nTPM]":"6.2","Cell RNA - K-562 [nTPM]":"10.1","Cell RNA - Karpas-707 [nTPM]":"3.5","Cell RNA - LHCN-M2 [nTPM]":"18.6","Cell RNA - MCF7 [nTPM]":"8.1","Cell RNA - MOLT-4 [nTPM]":"9.4","Cell RNA - NB-4 [nTPM]":"20.3","Cell RNA - NTERA-2 [nTPM]":"6.1","Cell RNA - OE19 [nTPM]":"7.1","Cell RNA - PC-3 [nTPM]":"10.8","Cell RNA - REH [nTPM]":"6.1","Cell RNA - RH-30 [nTPM]":"7.3","Cell RNA - RPMI-8226 [nTPM]":"24.9","Cell RNA - RPTEC TERT1 [nTPM]":"111.8","Cell RNA - RT4 [nTPM]":"28.5","Cell RNA - SCLC-21H [nTPM]":"7.2","Cell RNA - SH-SY5Y [nTPM]":"4.6","Cell RNA - SiHa [nTPM]":"3.1","Cell RNA - SK-BR-3 [nTPM]":"3.2","Cell RNA - SK-MEL-30 [nTPM]":"0.6","Cell RNA - SuSa [nTPM]":"36.8","Cell RNA - T-47d [nTPM]":"11.5","Cell RNA - THP-1 [nTPM]":"4.5","Cell RNA - TIME [nTPM]":"15.3","Cell RNA - U-138 MG [nTPM]":"9.7","Cell RNA - U-2 OS [nTPM]":"3.9","Cell RNA - U-2197 [nTPM]":"5.2","Cell RNA - U-251 MG [nTPM]":"6.2","Cell RNA - U-266\/70 [nTPM]":"3.9","Cell RNA - U-266\/84 [nTPM]":"6.0","Cell RNA - U-698 [nTPM]":"7.1","Cell RNA - U-87 MG [nTPM]":"19.3","Cell RNA - U-937 [nTPM]":"6.6","Cell RNA - WM-115 [nTPM]":"23.2","Blood RNA - basophil [nTPM]":"5.6","Blood RNA - classical monocyte [nTPM]":"9.2","Blood RNA - eosinophil [nTPM]":"8.6","Blood RNA - gdT-cell [nTPM]":"2.5","Blood RNA - intermediate monocyte [nTPM]":"7.3","Blood RNA - MAIT T-cell [nTPM]":"1.3","Blood RNA - memory B-cell [nTPM]":"4.0","Blood RNA - memory CD4 T-cell [nTPM]":"2.7","Blood RNA - memory CD8 T-cell [nTPM]":"3.0","Blood RNA - myeloid DC [nTPM]":"2.8","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"59.2","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"9.4","Blood RNA - plasmacytoid DC [nTPM]":"1.4","Blood RNA - T-reg [nTPM]":"8.7","Blood RNA - total PBMC [nTPM]":"4.6","Brain RNA - amygdala [nTPM]":"1.7","Brain RNA - basal ganglia [nTPM]":"6.9","Brain RNA - cerebellum [nTPM]":"5.0","Brain RNA - cerebral cortex [nTPM]":"7.7","Brain RNA - hippocampal formation [nTPM]":"3.5","Brain RNA - hypothalamus [nTPM]":"3.8","Brain RNA - medulla oblongata [nTPM]":"9.6","Brain RNA - midbrain [nTPM]":"6.6","Brain RNA - pons [nTPM]":"6.7","Brain RNA - spinal cord [nTPM]":"1.7","Brain RNA - thalamus [nTPM]":"11.0","Brain RNA - white matter [nTPM]":"6.8","Single Cell Type RNA - Adipocytes [nTPM]":"42.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.5","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"16.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"49.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"51.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"43.9","Single Cell Type RNA - Bipolar cells [nTPM]":"126.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"52.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"571.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.0","Single Cell Type RNA - dendritic cells [nTPM]":"14.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"12.0","Single Cell Type RNA - Early spermatids [nTPM]":"19.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"82.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.0","Single Cell Type RNA - Endothelial cells [nTPM]":"29.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.4","Single Cell Type RNA - Erythroid cells [nTPM]":"9.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.8","Single Cell Type RNA - Fibroblasts [nTPM]":"13.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"29.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"126.9","Single Cell Type RNA - granulocytes [nTPM]":"13.3","Single Cell Type RNA - Granulosa cells [nTPM]":"2.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"27.2","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.5","Single Cell Type RNA - Ionocytes [nTPM]":"46.8","Single Cell Type RNA - Kupffer cells [nTPM]":"60.1","Single Cell Type RNA - Langerhans cells [nTPM]":"59.5","Single Cell Type RNA - Late spermatids [nTPM]":"16.6","Single Cell Type RNA - Leydig cells [nTPM]":"17.4","Single Cell Type RNA - Macrophages [nTPM]":"58.8","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"32.8","Single Cell Type RNA - monocytes [nTPM]":"110.9","Single Cell Type RNA - Muller glia cells [nTPM]":"30.8","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"23.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"31.1","Single Cell Type RNA - Paneth cells [nTPM]":"12.6","Single Cell Type RNA - Peritubular cells [nTPM]":"17.3","Single Cell Type RNA - Plasma cells [nTPM]":"13.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"51.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"69.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"547.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"23.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.1","Single Cell Type RNA - T-cells [nTPM]":"25.5","Single Cell Type RNA - Theca cells [nTPM]":"46.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.6","Single Cell Type RNA - Urothelial cells [nTPM]":"16.8"},{"Gene":"SLC6A9","Gene synonym":["GLYT1"],"Ensembl":"ENSG00000196517","Gene description":"Solute carrier family 6 member 9","Uniprot":["P48067"],"Chromosome":"1","Position":"43991500-44031467","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Neurotransmitter transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"72.4","skin 1":"46.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"30.7","Distal enterocytes":"17.8","Erythroid cells":"33.1","Ionocytes":"20.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"18.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"62.3","hTCEpi":"106.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013977"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA013977":"AB_1849835"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.50e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.83e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.93e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.9","Tissue RNA - adrenal gland [nTPM]":"31.0","Tissue RNA - amygdala [nTPM]":"21.7","Tissue RNA - appendix [nTPM]":"4.9","Tissue RNA - basal ganglia [nTPM]":"45.5","Tissue RNA - bone marrow [nTPM]":"10.8","Tissue RNA - breast [nTPM]":"4.6","Tissue RNA - cerebellum [nTPM]":"53.2","Tissue RNA - cerebral cortex [nTPM]":"24.2","Tissue RNA - cervix [nTPM]":"12.1","Tissue RNA - choroid plexus [nTPM]":"6.3","Tissue RNA - colon [nTPM]":"11.0","Tissue RNA - duodenum [nTPM]":"2.3","Tissue RNA - endometrium 1 [nTPM]":"7.4","Tissue RNA - epididymis [nTPM]":"1.1","Tissue RNA - esophagus [nTPM]":"23.1","Tissue RNA - fallopian tube [nTPM]":"9.5","Tissue RNA - gallbladder [nTPM]":"4.8","Tissue RNA - heart muscle [nTPM]":"2.1","Tissue RNA - hippocampal formation [nTPM]":"16.1","Tissue RNA - hypothalamus [nTPM]":"31.3","Tissue RNA - kidney [nTPM]":"4.3","Tissue RNA - liver [nTPM]":"2.3","Tissue RNA - lung [nTPM]":"11.6","Tissue RNA - lymph node [nTPM]":"1.1","Tissue RNA - medulla oblongata [nTPM]":"66.3","Tissue RNA - midbrain [nTPM]":"43.5","Tissue RNA - ovary [nTPM]":"2.9","Tissue RNA - pancreas [nTPM]":"8.2","Tissue RNA - parathyroid gland [nTPM]":"2.8","Tissue RNA - pituitary gland [nTPM]":"1.7","Tissue RNA - placenta [nTPM]":"1.4","Tissue RNA - pons [nTPM]":"63.6","Tissue RNA - prostate [nTPM]":"3.9","Tissue RNA - rectum [nTPM]":"6.3","Tissue RNA - retina [nTPM]":"17.2","Tissue RNA - salivary gland [nTPM]":"11.5","Tissue RNA - seminal vesicle [nTPM]":"5.5","Tissue RNA - skeletal muscle [nTPM]":"1.1","Tissue RNA - skin 1 [nTPM]":"46.6","Tissue RNA - small intestine [nTPM]":"6.0","Tissue RNA - smooth muscle [nTPM]":"9.1","Tissue RNA - spinal cord [nTPM]":"45.6","Tissue RNA - spleen [nTPM]":"1.9","Tissue RNA - stomach 1 [nTPM]":"7.4","Tissue RNA - testis [nTPM]":"1.1","Tissue RNA - thalamus [nTPM]":"45.9","Tissue RNA - thymus [nTPM]":"1.4","Tissue RNA - thyroid gland [nTPM]":"5.3","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"4.3","Tissue RNA - urinary bladder [nTPM]":"12.3","Tissue RNA - vagina [nTPM]":"25.1","Tissue RNA - white matter [nTPM]":"72.4","Cell RNA - A-431 [nTPM]":"19.7","Cell RNA - A549 [nTPM]":"13.7","Cell RNA - AF22 [nTPM]":"7.1","Cell RNA - AN3-CA [nTPM]":"18.0","Cell RNA - ASC diff [nTPM]":"11.2","Cell RNA - ASC TERT1 [nTPM]":"3.7","Cell RNA - BEWO [nTPM]":"15.6","Cell RNA - BJ [nTPM]":"14.7","Cell RNA - BJ hTERT+ [nTPM]":"41.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"30.1","Cell RNA - CACO-2 [nTPM]":"4.8","Cell RNA - CAPAN-2 [nTPM]":"7.5","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"1.6","Cell RNA - fHDF\/TERT166 [nTPM]":"42.9","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"62.3","Cell RNA - HAP1 [nTPM]":"11.0","Cell RNA - HBEC3-KT [nTPM]":"12.5","Cell RNA - HBF TERT88 [nTPM]":"5.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"1.8","Cell RNA - HEL [nTPM]":"17.1","Cell RNA - HeLa [nTPM]":"33.9","Cell RNA - Hep G2 [nTPM]":"5.8","Cell RNA - HHSteC [nTPM]":"50.3","Cell RNA - HL-60 [nTPM]":"3.8","Cell RNA - HMC-1 [nTPM]":"0.7","Cell RNA - HSkMC [nTPM]":"11.3","Cell RNA - hTCEpi [nTPM]":"106.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.9","Cell RNA - hTERT-HME1 [nTPM]":"28.5","Cell RNA - hTERT-RPE1 [nTPM]":"15.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.6","Cell RNA - JURKAT [nTPM]":"12.3","Cell RNA - K-562 [nTPM]":"13.0","Cell RNA - Karpas-707 [nTPM]":"48.5","Cell RNA - LHCN-M2 [nTPM]":"1.0","Cell RNA - MCF7 [nTPM]":"10.4","Cell RNA - MOLT-4 [nTPM]":"2.9","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"5.4","Cell RNA - OE19 [nTPM]":"7.4","Cell RNA - PC-3 [nTPM]":"19.1","Cell RNA - REH [nTPM]":"2.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"22.9","Cell RNA - RPTEC TERT1 [nTPM]":"2.3","Cell RNA - RT4 [nTPM]":"2.2","Cell RNA - SCLC-21H [nTPM]":"4.4","Cell RNA - SH-SY5Y [nTPM]":"4.2","Cell RNA - SiHa [nTPM]":"7.4","Cell RNA - SK-BR-3 [nTPM]":"35.3","Cell RNA - SK-MEL-30 [nTPM]":"7.0","Cell RNA - SuSa [nTPM]":"1.7","Cell RNA - T-47d [nTPM]":"9.1","Cell RNA - THP-1 [nTPM]":"10.3","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"2.8","Cell RNA - U-2 OS [nTPM]":"11.0","Cell RNA - U-2197 [nTPM]":"2.4","Cell RNA - U-251 MG [nTPM]":"8.0","Cell RNA - U-266\/70 [nTPM]":"53.1","Cell RNA - U-266\/84 [nTPM]":"39.2","Cell RNA - U-698 [nTPM]":"4.4","Cell RNA - U-87 MG [nTPM]":"9.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"3.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"21.7","Brain RNA - basal ganglia [nTPM]":"45.5","Brain RNA - cerebellum [nTPM]":"53.2","Brain RNA - cerebral cortex [nTPM]":"24.2","Brain RNA - hippocampal formation [nTPM]":"16.1","Brain RNA - hypothalamus [nTPM]":"31.3","Brain RNA - medulla oblongata [nTPM]":"66.3","Brain RNA - midbrain [nTPM]":"43.5","Brain RNA - pons [nTPM]":"63.6","Brain RNA - spinal cord [nTPM]":"45.6","Brain RNA - thalamus [nTPM]":"45.9","Brain RNA - white matter [nTPM]":"72.4","Single Cell Type RNA - Adipocytes [nTPM]":"1.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.0","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"30.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"2.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.7","Single Cell Type RNA - Early spermatids [nTPM]":"5.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"33.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.7","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.2","Single Cell Type RNA - Paneth cells [nTPM]":"3.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"1.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"1.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.6","Single Cell Type RNA - Urothelial cells [nTPM]":"3.2"},{"Gene":"SLC7A14","Gene synonym":["KIAA1613","PPP1R142"],"Ensembl":"ENSG00000013293","Gene description":"Solute carrier family 7 member 14","Uniprot":["Q8TBB6"],"Chromosome":"3","Position":"170459548-170586075","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Transport"],"Molecular function":null,"Disease involvement":["Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"15.9","pituitary gland":"7.3","retina":"6.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Bipolar cells":"28.4","Excitatory neurons":"61.9","Horizontal cells":"28.6","Inhibitory neurons":"90.2","Oligodendrocytes":"67.4"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"glioma":"0.8","pancreatic cancer":"0.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"LHCN-M2":"3.2","SCLC-21H":"3.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045929"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":["Nucleoplasm","Plasma membrane"],"Antibody RRID":{"HPA045929":"AB_2679501"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"2.3","Tissue RNA - amygdala [nTPM]":"8.9","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"8.1","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"5.5","Tissue RNA - cerebral cortex [nTPM]":"8.8","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.5","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"7.9","Tissue RNA - hypothalamus [nTPM]":"15.9","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"15.6","Tissue RNA - midbrain [nTPM]":"6.4","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.7","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"7.3","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"14.9","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"6.1","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"4.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"8.9","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"7.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.5","Cell RNA - ASC TERT1 [nTPM]":"0.9","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.3","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.8","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.5","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"3.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"3.1","Cell RNA - SH-SY5Y [nTPM]":"0.9","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"8.9","Brain RNA - basal ganglia [nTPM]":"8.1","Brain RNA - cerebellum [nTPM]":"5.5","Brain RNA - cerebral cortex [nTPM]":"8.8","Brain RNA - hippocampal formation [nTPM]":"7.9","Brain RNA - hypothalamus [nTPM]":"15.9","Brain RNA - medulla oblongata [nTPM]":"15.6","Brain RNA - midbrain [nTPM]":"6.4","Brain RNA - pons [nTPM]":"14.9","Brain RNA - spinal cord [nTPM]":"4.0","Brain RNA - thalamus [nTPM]":"8.9","Brain RNA - white matter [nTPM]":"7.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.2","Single Cell Type RNA - Astrocytes [nTPM]":"4.6","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"28.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"61.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"28.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"90.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"67.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"SLC7A9","Gene synonym":["CSNU3"],"Ensembl":"ENSG00000021488","Gene description":"Solute carrier family 7 member 9","Uniprot":["P82251"],"Chromosome":"19","Position":"32830509-32869767","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Transport"],"Molecular function":null,"Disease involvement":["Cystinuria","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"intestine":"124.6","kidney":"68.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Proximal enterocytes":"772.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"liver cancer":"6.6","renal cancer":"5.2","stomach cancer":"1.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"16","RNA cell line specific nTPM":{"BEWO":"3.4","CACO-2":"8.2","Hep G2":"8.0"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042591"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042591":"AB_10962500"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-5"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.7","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.7","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"0.9","Tissue RNA - cervix [nTPM]":"0.8","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"0.8","Tissue RNA - duodenum [nTPM]":"78.3","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"1.4","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"0.7","Tissue RNA - kidney [nTPM]":"68.2","Tissue RNA - liver [nTPM]":"17.3","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.7","Tissue RNA - midbrain [nTPM]":"0.7","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.7","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.7","Tissue RNA - prostate [nTPM]":"1.0","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"1.0","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"124.6","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"0.7","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.8","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"0.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"3.4","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"8.2","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"8.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.7","Brain RNA - basal ganglia [nTPM]":"0.7","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"0.9","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"0.7","Brain RNA - medulla oblongata [nTPM]":"0.7","Brain RNA - midbrain [nTPM]":"0.7","Brain RNA - pons [nTPM]":"0.7","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"0.7","Brain RNA - white matter [nTPM]":"0.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.3","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.8","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"12.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"27.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"772.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"97.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.7","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SLC9A1","Gene synonym":["APNH","NHE1","PPP1R143"],"Ensembl":"ENSG00000090020","Gene description":"Solute carrier family 9 member A1","Uniprot":["P19634"],"Chromosome":"1","Position":"27098809-27166981","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Ion transport","Sodium transport","Transport"],"Molecular function":["Calmodulin-binding"],"Disease involvement":["Deafness","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"76.5","stomach 1":"65.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"81.5","Gastric mucus-secreting cells":"160.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022371","HPA048532","HPA052891"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"21000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB022371":null,"HPA048532":"AB_2680431","HPA052891":"AB_2681981"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.47e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.10e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.6","Tissue RNA - adrenal gland [nTPM]":"10.7","Tissue RNA - amygdala [nTPM]":"6.1","Tissue RNA - appendix [nTPM]":"10.4","Tissue RNA - basal ganglia [nTPM]":"14.7","Tissue RNA - bone marrow [nTPM]":"11.5","Tissue RNA - breast [nTPM]":"9.0","Tissue RNA - cerebellum [nTPM]":"2.8","Tissue RNA - cerebral cortex [nTPM]":"10.8","Tissue RNA - cervix [nTPM]":"10.9","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"18.6","Tissue RNA - duodenum [nTPM]":"29.3","Tissue RNA - endometrium 1 [nTPM]":"10.9","Tissue RNA - epididymis [nTPM]":"8.0","Tissue RNA - esophagus [nTPM]":"11.0","Tissue RNA - fallopian tube [nTPM]":"7.6","Tissue RNA - gallbladder [nTPM]":"16.9","Tissue RNA - heart muscle [nTPM]":"13.7","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"5.3","Tissue RNA - kidney [nTPM]":"5.8","Tissue RNA - liver [nTPM]":"2.4","Tissue RNA - lung [nTPM]":"13.2","Tissue RNA - lymph node [nTPM]":"7.0","Tissue RNA - medulla oblongata [nTPM]":"13.8","Tissue RNA - midbrain [nTPM]":"4.7","Tissue RNA - ovary [nTPM]":"7.0","Tissue RNA - pancreas [nTPM]":"8.6","Tissue RNA - parathyroid gland [nTPM]":"20.7","Tissue RNA - pituitary gland [nTPM]":"8.2","Tissue RNA - placenta [nTPM]":"21.9","Tissue RNA - pons [nTPM]":"11.2","Tissue RNA - prostate [nTPM]":"9.0","Tissue RNA - rectum [nTPM]":"13.6","Tissue RNA - retina [nTPM]":"4.5","Tissue RNA - salivary gland [nTPM]":"76.5","Tissue RNA - seminal vesicle [nTPM]":"19.4","Tissue RNA - skeletal muscle [nTPM]":"4.6","Tissue RNA - skin 1 [nTPM]":"10.5","Tissue RNA - small intestine [nTPM]":"19.0","Tissue RNA - smooth muscle [nTPM]":"10.7","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"11.6","Tissue RNA - stomach 1 [nTPM]":"65.9","Tissue RNA - testis [nTPM]":"10.1","Tissue RNA - thalamus [nTPM]":"10.4","Tissue RNA - thymus [nTPM]":"6.3","Tissue RNA - thyroid gland [nTPM]":"9.5","Tissue RNA - tongue [nTPM]":"4.9","Tissue RNA - tonsil [nTPM]":"6.7","Tissue RNA - urinary bladder [nTPM]":"15.1","Tissue RNA - vagina [nTPM]":"9.2","Tissue RNA - white matter [nTPM]":"2.4","Cell RNA - A-431 [nTPM]":"32.3","Cell RNA - A549 [nTPM]":"10.7","Cell RNA - AF22 [nTPM]":"9.9","Cell RNA - AN3-CA [nTPM]":"10.1","Cell RNA - ASC diff [nTPM]":"21.8","Cell RNA - ASC TERT1 [nTPM]":"15.7","Cell RNA - BEWO [nTPM]":"60.8","Cell RNA - BJ [nTPM]":"25.9","Cell RNA - BJ hTERT+ [nTPM]":"38.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.5","Cell RNA - CACO-2 [nTPM]":"13.0","Cell RNA - CAPAN-2 [nTPM]":"20.0","Cell RNA - Daudi [nTPM]":"14.4","Cell RNA - EFO-21 [nTPM]":"21.9","Cell RNA - fHDF\/TERT166 [nTPM]":"33.4","Cell RNA - GAMG [nTPM]":"10.5","Cell RNA - HaCaT [nTPM]":"38.9","Cell RNA - HAP1 [nTPM]":"9.8","Cell RNA - HBEC3-KT [nTPM]":"62.4","Cell RNA - HBF TERT88 [nTPM]":"13.4","Cell RNA - HDLM-2 [nTPM]":"17.4","Cell RNA - HEK 293 [nTPM]":"9.4","Cell RNA - HEL [nTPM]":"21.9","Cell RNA - HeLa [nTPM]":"7.1","Cell RNA - Hep G2 [nTPM]":"5.5","Cell RNA - HHSteC [nTPM]":"66.1","Cell RNA - HL-60 [nTPM]":"13.1","Cell RNA - HMC-1 [nTPM]":"16.0","Cell RNA - HSkMC [nTPM]":"19.7","Cell RNA - hTCEpi [nTPM]":"29.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"36.5","Cell RNA - hTERT-HME1 [nTPM]":"50.7","Cell RNA - hTERT-RPE1 [nTPM]":"15.8","Cell RNA - HUVEC TERT2 [nTPM]":"36.3","Cell RNA - JURKAT [nTPM]":"9.8","Cell RNA - K-562 [nTPM]":"6.3","Cell RNA - Karpas-707 [nTPM]":"13.4","Cell RNA - LHCN-M2 [nTPM]":"32.3","Cell RNA - MCF7 [nTPM]":"18.7","Cell RNA - MOLT-4 [nTPM]":"6.8","Cell RNA - NB-4 [nTPM]":"6.4","Cell RNA - NTERA-2 [nTPM]":"14.0","Cell RNA - OE19 [nTPM]":"38.2","Cell RNA - PC-3 [nTPM]":"21.9","Cell RNA - REH [nTPM]":"11.8","Cell RNA - RH-30 [nTPM]":"9.0","Cell RNA - RPMI-8226 [nTPM]":"6.7","Cell RNA - RPTEC TERT1 [nTPM]":"10.9","Cell RNA - RT4 [nTPM]":"46.3","Cell RNA - SCLC-21H [nTPM]":"11.4","Cell RNA - SH-SY5Y [nTPM]":"3.7","Cell RNA - SiHa [nTPM]":"21.5","Cell RNA - SK-BR-3 [nTPM]":"28.4","Cell RNA - SK-MEL-30 [nTPM]":"12.6","Cell RNA - SuSa [nTPM]":"10.0","Cell RNA - T-47d [nTPM]":"13.3","Cell RNA - THP-1 [nTPM]":"7.9","Cell RNA - TIME [nTPM]":"39.9","Cell RNA - U-138 MG [nTPM]":"23.0","Cell RNA - U-2 OS [nTPM]":"9.4","Cell RNA - U-2197 [nTPM]":"21.7","Cell RNA - U-251 MG [nTPM]":"14.5","Cell RNA - U-266\/70 [nTPM]":"12.6","Cell RNA - U-266\/84 [nTPM]":"8.6","Cell RNA - U-698 [nTPM]":"4.3","Cell RNA - U-87 MG [nTPM]":"24.6","Cell RNA - U-937 [nTPM]":"14.1","Cell RNA - WM-115 [nTPM]":"13.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"1.5","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"2.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"6.1","Brain RNA - basal ganglia [nTPM]":"14.7","Brain RNA - cerebellum [nTPM]":"2.8","Brain RNA - cerebral cortex [nTPM]":"10.8","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"5.3","Brain RNA - medulla oblongata [nTPM]":"13.8","Brain RNA - midbrain [nTPM]":"4.7","Brain RNA - pons [nTPM]":"11.2","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"10.4","Brain RNA - white matter [nTPM]":"2.4","Single Cell Type RNA - Adipocytes [nTPM]":"13.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.8","Single Cell Type RNA - Astrocytes [nTPM]":"6.5","Single Cell Type RNA - B-cells [nTPM]":"7.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"31.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Bipolar cells [nTPM]":"7.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"8.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"40.3","Single Cell Type RNA - dendritic cells [nTPM]":"11.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"81.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"9.1","Single Cell Type RNA - Early spermatids [nTPM]":"26.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.9","Single Cell Type RNA - Endothelial cells [nTPM]":"9.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.5","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.4","Single Cell Type RNA - Fibroblasts [nTPM]":"12.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"160.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.5","Single Cell Type RNA - granulocytes [nTPM]":"27.3","Single Cell Type RNA - Granulosa cells [nTPM]":"7.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"1.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.9","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"5.7","Single Cell Type RNA - Langerhans cells [nTPM]":"5.1","Single Cell Type RNA - Late spermatids [nTPM]":"14.4","Single Cell Type RNA - Leydig cells [nTPM]":"9.3","Single Cell Type RNA - Macrophages [nTPM]":"12.7","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"4.3","Single Cell Type RNA - Muller glia cells [nTPM]":"8.2","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"28.1","Single Cell Type RNA - Paneth cells [nTPM]":"43.1","Single Cell Type RNA - Peritubular cells [nTPM]":"13.2","Single Cell Type RNA - Plasma cells [nTPM]":"4.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"38.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.8","Single Cell Type RNA - Spermatocytes [nTPM]":"3.6","Single Cell Type RNA - Spermatogonia [nTPM]":"4.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"25.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"52.9","Single Cell Type RNA - T-cells [nTPM]":"9.8","Single Cell Type RNA - Theca cells [nTPM]":"4.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.3","Single Cell Type RNA - Urothelial cells [nTPM]":"18.3"},{"Gene":"SLC9A3R1","Gene synonym":["EBP50","NHERF","NHERF1"],"Ensembl":"ENSG00000109062","Gene description":"SLC9A3 regulator 1","Uniprot":["O14745"],"Chromosome":"17","Position":"74748628-74769353","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Wnt signaling pathway"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"352.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"295.8","Proximal enterocytes":"536.9","Proximal tubular cells":"433.0","Squamous epithelial cells":"303.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"572.4","SK-BR-3":"450.7","T-47d":"873.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB001962","HPA009672","HPA027247"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Centriolar satellite"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"940000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles","Centriolar satellite"],"Antibody RRID":{"CAB001962":null,"HPA009672":"AB_1857215","HPA027247":"AB_10601162"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.83e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.81e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Tissue RNA - adipose tissue [nTPM]":"27.0","Tissue RNA - adrenal gland [nTPM]":"146.3","Tissue RNA - amygdala [nTPM]":"98.9","Tissue RNA - appendix [nTPM]":"43.7","Tissue RNA - basal ganglia [nTPM]":"103.0","Tissue RNA - bone marrow [nTPM]":"115.7","Tissue RNA - breast [nTPM]":"64.1","Tissue RNA - cerebellum [nTPM]":"105.6","Tissue RNA - cerebral cortex [nTPM]":"118.1","Tissue RNA - cervix [nTPM]":"58.3","Tissue RNA - choroid plexus [nTPM]":"127.5","Tissue RNA - colon [nTPM]":"85.1","Tissue RNA - duodenum [nTPM]":"257.8","Tissue RNA - endometrium 1 [nTPM]":"22.6","Tissue RNA - epididymis [nTPM]":"26.0","Tissue RNA - esophagus [nTPM]":"352.8","Tissue RNA - fallopian tube [nTPM]":"89.7","Tissue RNA - gallbladder [nTPM]":"96.6","Tissue RNA - heart muscle [nTPM]":"24.3","Tissue RNA - hippocampal formation [nTPM]":"98.3","Tissue RNA - hypothalamus [nTPM]":"91.0","Tissue RNA - kidney [nTPM]":"203.5","Tissue RNA - liver [nTPM]":"269.2","Tissue RNA - lung [nTPM]":"26.5","Tissue RNA - lymph node [nTPM]":"67.9","Tissue RNA - medulla oblongata [nTPM]":"100.2","Tissue RNA - midbrain [nTPM]":"97.6","Tissue RNA - ovary [nTPM]":"11.1","Tissue RNA - pancreas [nTPM]":"85.4","Tissue RNA - parathyroid gland [nTPM]":"110.3","Tissue RNA - pituitary gland [nTPM]":"20.8","Tissue RNA - placenta [nTPM]":"33.6","Tissue RNA - pons [nTPM]":"95.6","Tissue RNA - prostate [nTPM]":"43.9","Tissue RNA - rectum [nTPM]":"59.3","Tissue RNA - retina [nTPM]":"13.0","Tissue RNA - salivary gland [nTPM]":"192.2","Tissue RNA - seminal vesicle [nTPM]":"71.1","Tissue RNA - skeletal muscle [nTPM]":"5.2","Tissue RNA - skin 1 [nTPM]":"51.1","Tissue RNA - small intestine [nTPM]":"274.4","Tissue RNA - smooth muscle [nTPM]":"11.6","Tissue RNA - spinal cord [nTPM]":"92.2","Tissue RNA - spleen [nTPM]":"61.1","Tissue RNA - stomach 1 [nTPM]":"78.2","Tissue RNA - testis [nTPM]":"22.5","Tissue RNA - thalamus [nTPM]":"102.0","Tissue RNA - thymus [nTPM]":"57.7","Tissue RNA - thyroid gland [nTPM]":"21.4","Tissue RNA - tongue [nTPM]":"10.0","Tissue RNA - tonsil [nTPM]":"89.2","Tissue RNA - urinary bladder [nTPM]":"25.7","Tissue RNA - vagina [nTPM]":"103.3","Tissue RNA - white matter [nTPM]":"106.1","Cell RNA - A-431 [nTPM]":"102.1","Cell RNA - A549 [nTPM]":"82.6","Cell RNA - AF22 [nTPM]":"40.4","Cell RNA - AN3-CA [nTPM]":"42.1","Cell RNA - ASC diff [nTPM]":"23.9","Cell RNA - ASC TERT1 [nTPM]":"17.5","Cell RNA - BEWO [nTPM]":"179.9","Cell RNA - BJ [nTPM]":"24.1","Cell RNA - BJ hTERT+ [nTPM]":"22.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"60.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"58.2","Cell RNA - CACO-2 [nTPM]":"259.6","Cell RNA - CAPAN-2 [nTPM]":"59.6","Cell RNA - Daudi [nTPM]":"22.2","Cell RNA - EFO-21 [nTPM]":"23.9","Cell RNA - fHDF\/TERT166 [nTPM]":"51.4","Cell RNA - GAMG [nTPM]":"32.3","Cell RNA - HaCaT [nTPM]":"142.2","Cell RNA - HAP1 [nTPM]":"69.8","Cell RNA - HBEC3-KT [nTPM]":"46.4","Cell RNA - HBF TERT88 [nTPM]":"28.3","Cell RNA - HDLM-2 [nTPM]":"25.9","Cell RNA - HEK 293 [nTPM]":"66.2","Cell RNA - HEL [nTPM]":"167.4","Cell RNA - HeLa [nTPM]":"210.9","Cell RNA - Hep G2 [nTPM]":"350.8","Cell RNA - HHSteC [nTPM]":"48.6","Cell RNA - HL-60 [nTPM]":"110.3","Cell RNA - HMC-1 [nTPM]":"108.9","Cell RNA - HSkMC [nTPM]":"14.4","Cell RNA - hTCEpi [nTPM]":"25.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"48.0","Cell RNA - hTERT-HME1 [nTPM]":"20.6","Cell RNA - hTERT-RPE1 [nTPM]":"124.9","Cell RNA - HUVEC TERT2 [nTPM]":"50.2","Cell RNA - JURKAT [nTPM]":"65.8","Cell RNA - K-562 [nTPM]":"54.0","Cell RNA - Karpas-707 [nTPM]":"115.9","Cell RNA - LHCN-M2 [nTPM]":"93.8","Cell RNA - MCF7 [nTPM]":"572.4","Cell RNA - MOLT-4 [nTPM]":"262.5","Cell RNA - NB-4 [nTPM]":"246.7","Cell RNA - NTERA-2 [nTPM]":"36.1","Cell RNA - OE19 [nTPM]":"286.3","Cell RNA - PC-3 [nTPM]":"47.6","Cell RNA - REH [nTPM]":"28.0","Cell RNA - RH-30 [nTPM]":"45.4","Cell RNA - RPMI-8226 [nTPM]":"100.6","Cell RNA - RPTEC TERT1 [nTPM]":"83.5","Cell RNA - RT4 [nTPM]":"71.7","Cell RNA - SCLC-21H [nTPM]":"34.6","Cell RNA - SH-SY5Y [nTPM]":"45.3","Cell RNA - SiHa [nTPM]":"25.2","Cell RNA - SK-BR-3 [nTPM]":"450.7","Cell RNA - SK-MEL-30 [nTPM]":"51.9","Cell RNA - SuSa [nTPM]":"110.4","Cell RNA - T-47d [nTPM]":"873.8","Cell RNA - THP-1 [nTPM]":"87.3","Cell RNA - TIME [nTPM]":"17.0","Cell RNA - U-138 MG [nTPM]":"18.7","Cell RNA - U-2 OS [nTPM]":"53.5","Cell RNA - U-2197 [nTPM]":"43.8","Cell RNA - U-251 MG [nTPM]":"40.2","Cell RNA - U-266\/70 [nTPM]":"200.0","Cell RNA - U-266\/84 [nTPM]":"98.9","Cell RNA - U-698 [nTPM]":"40.9","Cell RNA - U-87 MG [nTPM]":"30.2","Cell RNA - U-937 [nTPM]":"145.4","Cell RNA - WM-115 [nTPM]":"11.2","Blood RNA - basophil [nTPM]":"581.6","Blood RNA - classical monocyte [nTPM]":"91.9","Blood RNA - eosinophil [nTPM]":"440.8","Blood RNA - gdT-cell [nTPM]":"421.5","Blood RNA - intermediate monocyte [nTPM]":"133.0","Blood RNA - MAIT T-cell [nTPM]":"279.8","Blood RNA - memory B-cell [nTPM]":"58.6","Blood RNA - memory CD4 T-cell [nTPM]":"255.5","Blood RNA - memory CD8 T-cell [nTPM]":"360.4","Blood RNA - myeloid DC [nTPM]":"87.8","Blood RNA - naive B-cell [nTPM]":"52.1","Blood RNA - naive CD4 T-cell [nTPM]":"147.5","Blood RNA - naive CD8 T-cell [nTPM]":"266.1","Blood RNA - neutrophil [nTPM]":"318.8","Blood RNA - NK-cell [nTPM]":"308.8","Blood RNA - non-classical monocyte [nTPM]":"172.1","Blood RNA - plasmacytoid DC [nTPM]":"90.8","Blood RNA - T-reg [nTPM]":"309.0","Blood RNA - total PBMC [nTPM]":"345.9","Brain RNA - amygdala [nTPM]":"98.9","Brain RNA - basal ganglia [nTPM]":"103.0","Brain RNA - cerebellum [nTPM]":"105.6","Brain RNA - cerebral cortex [nTPM]":"118.1","Brain RNA - hippocampal formation [nTPM]":"98.3","Brain RNA - hypothalamus [nTPM]":"91.0","Brain RNA - medulla oblongata [nTPM]":"100.2","Brain RNA - midbrain [nTPM]":"97.6","Brain RNA - pons [nTPM]":"95.6","Brain RNA - spinal cord [nTPM]":"92.2","Brain RNA - thalamus [nTPM]":"102.0","Brain RNA - white matter [nTPM]":"106.1","Single Cell Type RNA - Adipocytes [nTPM]":"12.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.2","Single Cell Type RNA - Astrocytes [nTPM]":"29.0","Single Cell Type RNA - B-cells [nTPM]":"41.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"46.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"128.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"50.1","Single Cell Type RNA - Bipolar cells [nTPM]":"2.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"135.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"78.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"163.0","Single Cell Type RNA - Club cells [nTPM]":"120.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"74.5","Single Cell Type RNA - dendritic cells [nTPM]":"122.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"295.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"66.5","Single Cell Type RNA - Ductal cells [nTPM]":"194.9","Single Cell Type RNA - Early spermatids [nTPM]":"15.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"61.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.8","Single Cell Type RNA - Endothelial cells [nTPM]":"12.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.7","Single Cell Type RNA - Erythroid cells [nTPM]":"24.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"99.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"56.6","Single Cell Type RNA - Fibroblasts [nTPM]":"24.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"45.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"85.0","Single Cell Type RNA - granulocytes [nTPM]":"25.3","Single Cell Type RNA - Granulosa cells [nTPM]":"7.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"190.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"85.4","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"58.0","Single Cell Type RNA - Ionocytes [nTPM]":"105.8","Single Cell Type RNA - Kupffer cells [nTPM]":"25.7","Single Cell Type RNA - Langerhans cells [nTPM]":"18.8","Single Cell Type RNA - Late spermatids [nTPM]":"9.9","Single Cell Type RNA - Leydig cells [nTPM]":"8.7","Single Cell Type RNA - Macrophages [nTPM]":"43.5","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"27.0","Single Cell Type RNA - Muller glia cells [nTPM]":"86.2","Single Cell Type RNA - NK-cells [nTPM]":"203.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"76.5","Single Cell Type RNA - Paneth cells [nTPM]":"143.8","Single Cell Type RNA - Peritubular cells [nTPM]":"41.8","Single Cell Type RNA - Plasma cells [nTPM]":"151.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"27.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"536.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"433.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"76.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.0","Single Cell Type RNA - Spermatocytes [nTPM]":"22.5","Single Cell Type RNA - Spermatogonia [nTPM]":"19.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"303.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"57.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"111.5","Single Cell Type RNA - T-cells [nTPM]":"126.1","Single Cell Type RNA - Theca cells [nTPM]":"17.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"57.1","Single Cell Type RNA - Urothelial cells [nTPM]":"34.6"},{"Gene":"SLC9A6","Gene synonym":["KIAA0267","NHE6"],"Ensembl":"ENSG00000198689","Gene description":"Solute carrier family 9 member A6","Uniprot":["Q92581"],"Chromosome":"X","Position":"135973841-136047269","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Ion transport","Sodium transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"40.3","Horizontal cells":"48.8","Inhibitory neurons":"42.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059445","HPA059590"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 62: Horizontal cells - Visual perception","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA059445":"AB_2684021","HPA059590":"AB_2684075"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.1","Tissue RNA - adrenal gland [nTPM]":"6.3","Tissue RNA - amygdala [nTPM]":"11.6","Tissue RNA - appendix [nTPM]":"5.6","Tissue RNA - basal ganglia [nTPM]":"11.9","Tissue RNA - bone marrow [nTPM]":"4.6","Tissue RNA - breast [nTPM]":"3.3","Tissue RNA - cerebellum [nTPM]":"1.2","Tissue RNA - cerebral cortex [nTPM]":"15.7","Tissue RNA - cervix [nTPM]":"5.6","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"6.0","Tissue RNA - duodenum [nTPM]":"8.5","Tissue RNA - endometrium 1 [nTPM]":"6.4","Tissue RNA - epididymis [nTPM]":"3.3","Tissue RNA - esophagus [nTPM]":"6.3","Tissue RNA - fallopian tube [nTPM]":"5.7","Tissue RNA - gallbladder [nTPM]":"5.5","Tissue RNA - heart muscle [nTPM]":"8.6","Tissue RNA - hippocampal formation [nTPM]":"12.7","Tissue RNA - hypothalamus [nTPM]":"19.0","Tissue RNA - kidney [nTPM]":"6.9","Tissue RNA - liver [nTPM]":"4.5","Tissue RNA - lung [nTPM]":"6.7","Tissue RNA - lymph node [nTPM]":"5.7","Tissue RNA - medulla oblongata [nTPM]":"7.8","Tissue RNA - midbrain [nTPM]":"4.4","Tissue RNA - ovary [nTPM]":"8.0","Tissue RNA - pancreas [nTPM]":"3.8","Tissue RNA - parathyroid gland [nTPM]":"10.4","Tissue RNA - pituitary gland [nTPM]":"2.2","Tissue RNA - placenta [nTPM]":"4.7","Tissue RNA - pons [nTPM]":"8.9","Tissue RNA - prostate [nTPM]":"4.0","Tissue RNA - rectum [nTPM]":"6.1","Tissue RNA - retina [nTPM]":"14.4","Tissue RNA - salivary gland [nTPM]":"4.1","Tissue RNA - seminal vesicle [nTPM]":"4.9","Tissue RNA - skeletal muscle [nTPM]":"7.5","Tissue RNA - skin 1 [nTPM]":"4.7","Tissue RNA - small intestine [nTPM]":"7.8","Tissue RNA - smooth muscle [nTPM]":"7.4","Tissue RNA - spinal cord [nTPM]":"3.4","Tissue RNA - spleen [nTPM]":"5.7","Tissue RNA - stomach 1 [nTPM]":"5.8","Tissue RNA - testis [nTPM]":"5.8","Tissue RNA - thalamus [nTPM]":"15.3","Tissue RNA - thymus [nTPM]":"5.6","Tissue RNA - thyroid gland [nTPM]":"6.7","Tissue RNA - tongue [nTPM]":"7.1","Tissue RNA - tonsil [nTPM]":"6.6","Tissue RNA - urinary bladder [nTPM]":"5.6","Tissue RNA - vagina [nTPM]":"1.6","Tissue RNA - white matter [nTPM]":"4.2","Cell RNA - A-431 [nTPM]":"20.0","Cell RNA - A549 [nTPM]":"10.5","Cell RNA - AF22 [nTPM]":"9.1","Cell RNA - AN3-CA [nTPM]":"3.8","Cell RNA - ASC diff [nTPM]":"14.8","Cell RNA - ASC TERT1 [nTPM]":"14.2","Cell RNA - BEWO [nTPM]":"17.3","Cell RNA - BJ [nTPM]":"15.9","Cell RNA - BJ hTERT+ [nTPM]":"16.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"27.9","Cell RNA - CACO-2 [nTPM]":"9.2","Cell RNA - CAPAN-2 [nTPM]":"15.5","Cell RNA - Daudi [nTPM]":"14.8","Cell RNA - EFO-21 [nTPM]":"35.2","Cell RNA - fHDF\/TERT166 [nTPM]":"18.4","Cell RNA - GAMG [nTPM]":"19.8","Cell RNA - HaCaT [nTPM]":"11.6","Cell RNA - HAP1 [nTPM]":"14.3","Cell RNA - HBEC3-KT [nTPM]":"14.0","Cell RNA - HBF TERT88 [nTPM]":"19.1","Cell RNA - HDLM-2 [nTPM]":"11.7","Cell RNA - HEK 293 [nTPM]":"12.9","Cell RNA - HEL [nTPM]":"4.0","Cell RNA - HeLa [nTPM]":"15.3","Cell RNA - Hep G2 [nTPM]":"5.3","Cell RNA - HHSteC [nTPM]":"7.9","Cell RNA - HL-60 [nTPM]":"11.6","Cell RNA - HMC-1 [nTPM]":"13.3","Cell RNA - HSkMC [nTPM]":"7.7","Cell RNA - hTCEpi [nTPM]":"11.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.0","Cell RNA - hTERT-HME1 [nTPM]":"10.8","Cell RNA - hTERT-RPE1 [nTPM]":"9.4","Cell RNA - HUVEC TERT2 [nTPM]":"11.2","Cell RNA - JURKAT [nTPM]":"12.5","Cell RNA - K-562 [nTPM]":"7.5","Cell RNA - Karpas-707 [nTPM]":"20.5","Cell RNA - LHCN-M2 [nTPM]":"14.9","Cell RNA - MCF7 [nTPM]":"8.7","Cell RNA - MOLT-4 [nTPM]":"15.5","Cell RNA - NB-4 [nTPM]":"3.4","Cell RNA - NTERA-2 [nTPM]":"6.0","Cell RNA - OE19 [nTPM]":"7.1","Cell RNA - PC-3 [nTPM]":"14.0","Cell RNA - REH [nTPM]":"10.4","Cell RNA - RH-30 [nTPM]":"16.0","Cell RNA - RPMI-8226 [nTPM]":"15.2","Cell RNA - RPTEC TERT1 [nTPM]":"9.4","Cell RNA - RT4 [nTPM]":"9.8","Cell RNA - SCLC-21H [nTPM]":"9.5","Cell RNA - SH-SY5Y [nTPM]":"7.2","Cell RNA - SiHa [nTPM]":"11.4","Cell RNA - SK-BR-3 [nTPM]":"1.2","Cell RNA - SK-MEL-30 [nTPM]":"8.9","Cell RNA - SuSa [nTPM]":"8.8","Cell RNA - T-47d [nTPM]":"4.5","Cell RNA - THP-1 [nTPM]":"8.7","Cell RNA - TIME [nTPM]":"16.4","Cell RNA - U-138 MG [nTPM]":"16.5","Cell RNA - U-2 OS [nTPM]":"10.9","Cell RNA - U-2197 [nTPM]":"24.5","Cell RNA - U-251 MG [nTPM]":"20.7","Cell RNA - U-266\/70 [nTPM]":"9.6","Cell RNA - U-266\/84 [nTPM]":"23.8","Cell RNA - U-698 [nTPM]":"12.7","Cell RNA - U-87 MG [nTPM]":"10.0","Cell RNA - U-937 [nTPM]":"19.4","Cell RNA - WM-115 [nTPM]":"9.4","Blood RNA - basophil [nTPM]":"2.0","Blood RNA - classical monocyte [nTPM]":"5.0","Blood RNA - eosinophil [nTPM]":"3.0","Blood RNA - gdT-cell [nTPM]":"6.4","Blood RNA - intermediate monocyte [nTPM]":"7.0","Blood RNA - MAIT T-cell [nTPM]":"11.1","Blood RNA - memory B-cell [nTPM]":"4.1","Blood RNA - memory CD4 T-cell [nTPM]":"7.1","Blood RNA - memory CD8 T-cell [nTPM]":"5.9","Blood RNA - myeloid DC [nTPM]":"5.8","Blood RNA - naive B-cell [nTPM]":"2.6","Blood RNA - naive CD4 T-cell [nTPM]":"7.6","Blood RNA - naive CD8 T-cell [nTPM]":"5.7","Blood RNA - neutrophil [nTPM]":"2.0","Blood RNA - NK-cell [nTPM]":"5.1","Blood RNA - non-classical monocyte [nTPM]":"6.0","Blood RNA - plasmacytoid DC [nTPM]":"3.5","Blood RNA - T-reg [nTPM]":"6.9","Blood RNA - total PBMC [nTPM]":"5.4","Brain RNA - amygdala [nTPM]":"11.6","Brain RNA - basal ganglia [nTPM]":"11.9","Brain RNA - cerebellum [nTPM]":"1.2","Brain RNA - cerebral cortex [nTPM]":"15.7","Brain RNA - hippocampal formation [nTPM]":"12.7","Brain RNA - hypothalamus [nTPM]":"19.0","Brain RNA - medulla oblongata [nTPM]":"7.8","Brain RNA - midbrain [nTPM]":"4.4","Brain RNA - pons [nTPM]":"8.9","Brain RNA - spinal cord [nTPM]":"3.4","Brain RNA - thalamus [nTPM]":"15.3","Brain RNA - white matter [nTPM]":"4.2","Single Cell Type RNA - Adipocytes [nTPM]":"4.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.4","Single Cell Type RNA - Astrocytes [nTPM]":"22.9","Single Cell Type RNA - B-cells [nTPM]":"5.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"14.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"4.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - dendritic cells [nTPM]":"6.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"4.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.1","Single Cell Type RNA - Endothelial cells [nTPM]":"4.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.7","Single Cell Type RNA - Erythroid cells [nTPM]":"5.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"40.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.4","Single Cell Type RNA - Fibroblasts [nTPM]":"5.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.8","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"4.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.2","Single Cell Type RNA - Hepatocytes [nTPM]":"9.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.9","Single Cell Type RNA - Horizontal cells [nTPM]":"48.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"42.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.0","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"13.0","Single Cell Type RNA - Langerhans cells [nTPM]":"7.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"5.6","Single Cell Type RNA - Macrophages [nTPM]":"9.8","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"8.2","Single Cell Type RNA - Muller glia cells [nTPM]":"12.9","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"22.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.1","Single Cell Type RNA - Paneth cells [nTPM]":"6.0","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"3.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.4","Single Cell Type RNA - Spermatocytes [nTPM]":"9.0","Single Cell Type RNA - Spermatogonia [nTPM]":"11.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.9","Single Cell Type RNA - T-cells [nTPM]":"8.9","Single Cell Type RNA - Theca cells [nTPM]":"3.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.0","Single Cell Type RNA - Urothelial cells [nTPM]":"3.1"},{"Gene":"SLC9A7","Gene synonym":["NHE7"],"Ensembl":"ENSG00000065923","Gene description":"Solute carrier family 9 member A7","Uniprot":["Q96T83"],"Chromosome":"X","Position":"46599251-46759118","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Ion transport","Potassium transport","Sodium transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"41.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"43.3","Inhibitory neurons":"66.8","Oligodendrocyte precursor cells":"69.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"2.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048938","HPA075385"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA048938":"AB_2680565","HPA075385":"AB_2686747"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.58e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.14e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"5.0","Tissue RNA - amygdala [nTPM]":"9.1","Tissue RNA - appendix [nTPM]":"2.4","Tissue RNA - basal ganglia [nTPM]":"41.6","Tissue RNA - bone marrow [nTPM]":"3.6","Tissue RNA - breast [nTPM]":"5.8","Tissue RNA - cerebellum [nTPM]":"6.3","Tissue RNA - cerebral cortex [nTPM]":"14.6","Tissue RNA - cervix [nTPM]":"1.2","Tissue RNA - choroid plexus [nTPM]":"0.5","Tissue RNA - colon [nTPM]":"0.6","Tissue RNA - duodenum [nTPM]":"1.2","Tissue RNA - endometrium 1 [nTPM]":"0.8","Tissue RNA - epididymis [nTPM]":"2.6","Tissue RNA - esophagus [nTPM]":"1.9","Tissue RNA - fallopian tube [nTPM]":"1.7","Tissue RNA - gallbladder [nTPM]":"1.6","Tissue RNA - heart muscle [nTPM]":"1.1","Tissue RNA - hippocampal formation [nTPM]":"8.6","Tissue RNA - hypothalamus [nTPM]":"17.0","Tissue RNA - kidney [nTPM]":"2.6","Tissue RNA - liver [nTPM]":"3.1","Tissue RNA - lung [nTPM]":"1.3","Tissue RNA - lymph node [nTPM]":"6.3","Tissue RNA - medulla oblongata [nTPM]":"13.9","Tissue RNA - midbrain [nTPM]":"7.5","Tissue RNA - ovary [nTPM]":"4.3","Tissue RNA - pancreas [nTPM]":"3.4","Tissue RNA - parathyroid gland [nTPM]":"8.9","Tissue RNA - pituitary gland [nTPM]":"9.2","Tissue RNA - placenta [nTPM]":"1.1","Tissue RNA - pons [nTPM]":"14.2","Tissue RNA - prostate [nTPM]":"4.6","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"4.9","Tissue RNA - salivary gland [nTPM]":"6.0","Tissue RNA - seminal vesicle [nTPM]":"2.0","Tissue RNA - skeletal muscle [nTPM]":"5.7","Tissue RNA - skin 1 [nTPM]":"2.1","Tissue RNA - small intestine [nTPM]":"2.2","Tissue RNA - smooth muscle [nTPM]":"0.7","Tissue RNA - spinal cord [nTPM]":"6.7","Tissue RNA - spleen [nTPM]":"3.7","Tissue RNA - stomach 1 [nTPM]":"6.3","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"14.5","Tissue RNA - thymus [nTPM]":"3.2","Tissue RNA - thyroid gland [nTPM]":"4.3","Tissue RNA - tongue [nTPM]":"2.5","Tissue RNA - tonsil [nTPM]":"6.3","Tissue RNA - urinary bladder [nTPM]":"1.8","Tissue RNA - vagina [nTPM]":"1.3","Tissue RNA - white matter [nTPM]":"5.1","Cell RNA - A-431 [nTPM]":"10.4","Cell RNA - A549 [nTPM]":"7.7","Cell RNA - AF22 [nTPM]":"1.1","Cell RNA - AN3-CA [nTPM]":"3.3","Cell RNA - ASC diff [nTPM]":"1.2","Cell RNA - ASC TERT1 [nTPM]":"7.4","Cell RNA - BEWO [nTPM]":"4.3","Cell RNA - BJ [nTPM]":"9.6","Cell RNA - BJ hTERT+ [nTPM]":"12.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.5","Cell RNA - CACO-2 [nTPM]":"7.9","Cell RNA - CAPAN-2 [nTPM]":"10.9","Cell RNA - Daudi [nTPM]":"22.7","Cell RNA - EFO-21 [nTPM]":"2.9","Cell RNA - fHDF\/TERT166 [nTPM]":"15.6","Cell RNA - GAMG [nTPM]":"11.0","Cell RNA - HaCaT [nTPM]":"4.6","Cell RNA - HAP1 [nTPM]":"7.4","Cell RNA - HBEC3-KT [nTPM]":"10.9","Cell RNA - HBF TERT88 [nTPM]":"10.3","Cell RNA - HDLM-2 [nTPM]":"11.9","Cell RNA - HEK 293 [nTPM]":"3.9","Cell RNA - HEL [nTPM]":"2.3","Cell RNA - HeLa [nTPM]":"3.1","Cell RNA - Hep G2 [nTPM]":"3.3","Cell RNA - HHSteC [nTPM]":"4.6","Cell RNA - HL-60 [nTPM]":"1.0","Cell RNA - HMC-1 [nTPM]":"17.9","Cell RNA - HSkMC [nTPM]":"4.6","Cell RNA - hTCEpi [nTPM]":"1.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.1","Cell RNA - hTERT-HME1 [nTPM]":"10.6","Cell RNA - hTERT-RPE1 [nTPM]":"26.8","Cell RNA - HUVEC TERT2 [nTPM]":"8.2","Cell RNA - JURKAT [nTPM]":"7.7","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"7.9","Cell RNA - MCF7 [nTPM]":"15.7","Cell RNA - MOLT-4 [nTPM]":"2.6","Cell RNA - NB-4 [nTPM]":"1.2","Cell RNA - NTERA-2 [nTPM]":"5.3","Cell RNA - OE19 [nTPM]":"5.0","Cell RNA - PC-3 [nTPM]":"9.2","Cell RNA - REH [nTPM]":"10.0","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"4.4","Cell RNA - RT4 [nTPM]":"11.4","Cell RNA - SCLC-21H [nTPM]":"8.2","Cell RNA - SH-SY5Y [nTPM]":"1.0","Cell RNA - SiHa [nTPM]":"4.9","Cell RNA - SK-BR-3 [nTPM]":"7.3","Cell RNA - SK-MEL-30 [nTPM]":"2.1","Cell RNA - SuSa [nTPM]":"9.2","Cell RNA - T-47d [nTPM]":"9.7","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"12.0","Cell RNA - U-2 OS [nTPM]":"4.0","Cell RNA - U-2197 [nTPM]":"1.8","Cell RNA - U-251 MG [nTPM]":"5.7","Cell RNA - U-266\/70 [nTPM]":"2.3","Cell RNA - U-266\/84 [nTPM]":"0.5","Cell RNA - U-698 [nTPM]":"11.2","Cell RNA - U-87 MG [nTPM]":"17.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"4.0","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"1.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"1.1","Blood RNA - naive B-cell [nTPM]":"1.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"2.8","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"9.1","Brain RNA - basal ganglia [nTPM]":"41.6","Brain RNA - cerebellum [nTPM]":"6.3","Brain RNA - cerebral cortex [nTPM]":"14.6","Brain RNA - hippocampal formation [nTPM]":"8.6","Brain RNA - hypothalamus [nTPM]":"17.0","Brain RNA - medulla oblongata [nTPM]":"13.9","Brain RNA - midbrain [nTPM]":"7.5","Brain RNA - pons [nTPM]":"14.2","Brain RNA - spinal cord [nTPM]":"6.7","Brain RNA - thalamus [nTPM]":"14.5","Brain RNA - white matter [nTPM]":"5.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.2","Single Cell Type RNA - Astrocytes [nTPM]":"11.4","Single Cell Type RNA - B-cells [nTPM]":"21.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"13.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"2.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.9","Single Cell Type RNA - dendritic cells [nTPM]":"24.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"17.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"5.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"43.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"2.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"4.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"6.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.4","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"66.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"6.3","Single Cell Type RNA - Langerhans cells [nTPM]":"8.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"9.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"8.0","Single Cell Type RNA - Muller glia cells [nTPM]":"6.1","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"69.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"2.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"21.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"1.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.3","Single Cell Type RNA - T-cells [nTPM]":"2.9","Single Cell Type RNA - Theca cells [nTPM]":"1.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.9","Single Cell Type RNA - Urothelial cells [nTPM]":"11.5"},{"Gene":"SLC9A9","Gene synonym":["FLJ35613","NHE9"],"Ensembl":"ENSG00000181804","Gene description":"Solute carrier family 9 member A9","Uniprot":["Q8IVB4"],"Chromosome":"3","Position":"143265222-143848485","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Ion transport","Sodium transport","Transport"],"Molecular function":null,"Disease involvement":["Autism","Autism spectrum disorder"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Astrocytes":"149.8","Inhibitory neurons":"159.5","Microglial cells":"396.3","Oligodendrocyte precursor cells":"272.9","Oligodendrocytes":"431.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"19.3","ASC TERT1":"24.9","HSkMC":"17.6","Karpas-707":"62.8","RPMI-8226":"30.4","U-266\/70":"29.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058234"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"280000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA058234":"AB_2683648"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.23e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.18e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.57e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Tissue RNA - adipose tissue [nTPM]":"12.8","Tissue RNA - adrenal gland [nTPM]":"5.1","Tissue RNA - amygdala [nTPM]":"9.7","Tissue RNA - appendix [nTPM]":"8.8","Tissue RNA - basal ganglia [nTPM]":"14.4","Tissue RNA - bone marrow [nTPM]":"2.0","Tissue RNA - breast [nTPM]":"5.3","Tissue RNA - cerebellum [nTPM]":"12.5","Tissue RNA - cerebral cortex [nTPM]":"11.3","Tissue RNA - cervix [nTPM]":"6.9","Tissue RNA - choroid plexus [nTPM]":"6.9","Tissue RNA - colon [nTPM]":"7.3","Tissue RNA - duodenum [nTPM]":"3.0","Tissue RNA - endometrium 1 [nTPM]":"4.2","Tissue RNA - epididymis [nTPM]":"3.7","Tissue RNA - esophagus [nTPM]":"12.8","Tissue RNA - fallopian tube [nTPM]":"6.8","Tissue RNA - gallbladder [nTPM]":"9.6","Tissue RNA - heart muscle [nTPM]":"5.4","Tissue RNA - hippocampal formation [nTPM]":"9.9","Tissue RNA - hypothalamus [nTPM]":"16.3","Tissue RNA - kidney [nTPM]":"2.3","Tissue RNA - liver [nTPM]":"7.1","Tissue RNA - lung [nTPM]":"5.9","Tissue RNA - lymph node [nTPM]":"14.7","Tissue RNA - medulla oblongata [nTPM]":"20.4","Tissue RNA - midbrain [nTPM]":"13.5","Tissue RNA - ovary [nTPM]":"7.9","Tissue RNA - pancreas [nTPM]":"1.0","Tissue RNA - parathyroid gland [nTPM]":"3.0","Tissue RNA - pituitary gland [nTPM]":"3.4","Tissue RNA - placenta [nTPM]":"15.9","Tissue RNA - pons [nTPM]":"19.5","Tissue RNA - prostate [nTPM]":"8.8","Tissue RNA - rectum [nTPM]":"5.8","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"4.5","Tissue RNA - seminal vesicle [nTPM]":"8.5","Tissue RNA - skeletal muscle [nTPM]":"2.1","Tissue RNA - skin 1 [nTPM]":"7.7","Tissue RNA - small intestine [nTPM]":"7.0","Tissue RNA - smooth muscle [nTPM]":"8.0","Tissue RNA - spinal cord [nTPM]":"14.4","Tissue RNA - spleen [nTPM]":"13.1","Tissue RNA - stomach 1 [nTPM]":"5.0","Tissue RNA - testis [nTPM]":"1.8","Tissue RNA - thalamus [nTPM]":"13.8","Tissue RNA - thymus [nTPM]":"15.5","Tissue RNA - thyroid gland [nTPM]":"3.5","Tissue RNA - tongue [nTPM]":"5.0","Tissue RNA - tonsil [nTPM]":"13.5","Tissue RNA - urinary bladder [nTPM]":"11.4","Tissue RNA - vagina [nTPM]":"7.7","Tissue RNA - white matter [nTPM]":"18.2","Cell RNA - A-431 [nTPM]":"0.5","Cell RNA - A549 [nTPM]":"0.5","Cell RNA - AF22 [nTPM]":"0.8","Cell RNA - AN3-CA [nTPM]":"1.0","Cell RNA - ASC diff [nTPM]":"19.3","Cell RNA - ASC TERT1 [nTPM]":"24.9","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"1.0","Cell RNA - BJ hTERT+ [nTPM]":"6.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"3.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"2.9","Cell RNA - GAMG [nTPM]":"1.5","Cell RNA - HaCaT [nTPM]":"0.7","Cell RNA - HAP1 [nTPM]":"0.9","Cell RNA - HBEC3-KT [nTPM]":"1.9","Cell RNA - HBF TERT88 [nTPM]":"0.8","Cell RNA - HDLM-2 [nTPM]":"12.8","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"1.6","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"2.2","Cell RNA - HL-60 [nTPM]":"0.8","Cell RNA - HMC-1 [nTPM]":"1.3","Cell RNA - HSkMC [nTPM]":"17.6","Cell RNA - hTCEpi [nTPM]":"5.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.7","Cell RNA - hTERT-HME1 [nTPM]":"0.9","Cell RNA - hTERT-RPE1 [nTPM]":"1.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"2.3","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"62.8","Cell RNA - LHCN-M2 [nTPM]":"4.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"1.5","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.5","Cell RNA - REH [nTPM]":"2.6","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"30.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"1.5","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.6","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"2.4","Cell RNA - U-2 OS [nTPM]":"0.6","Cell RNA - U-2197 [nTPM]":"2.8","Cell RNA - U-251 MG [nTPM]":"1.4","Cell RNA - U-266\/70 [nTPM]":"29.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"4.3","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"1.2","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"6.2","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"4.7","Blood RNA - intermediate monocyte [nTPM]":"10.6","Blood RNA - MAIT T-cell [nTPM]":"4.0","Blood RNA - memory B-cell [nTPM]":"3.3","Blood RNA - memory CD4 T-cell [nTPM]":"4.9","Blood RNA - memory CD8 T-cell [nTPM]":"7.5","Blood RNA - myeloid DC [nTPM]":"8.4","Blood RNA - naive B-cell [nTPM]":"3.7","Blood RNA - naive CD4 T-cell [nTPM]":"2.7","Blood RNA - naive CD8 T-cell [nTPM]":"4.0","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"4.2","Blood RNA - non-classical monocyte [nTPM]":"9.0","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"9.3","Blood RNA - total PBMC [nTPM]":"4.8","Brain RNA - amygdala [nTPM]":"9.7","Brain RNA - basal ganglia [nTPM]":"14.4","Brain RNA - cerebellum [nTPM]":"12.5","Brain RNA - cerebral cortex [nTPM]":"11.3","Brain RNA - hippocampal formation [nTPM]":"9.9","Brain RNA - hypothalamus [nTPM]":"16.3","Brain RNA - medulla oblongata [nTPM]":"20.4","Brain RNA - midbrain [nTPM]":"13.5","Brain RNA - pons [nTPM]":"19.5","Brain RNA - spinal cord [nTPM]":"14.4","Brain RNA - thalamus [nTPM]":"13.8","Brain RNA - white matter [nTPM]":"18.2","Single Cell Type RNA - Adipocytes [nTPM]":"4.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"149.8","Single Cell Type RNA - B-cells [nTPM]":"13.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"10.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.0","Single Cell Type RNA - Early spermatids [nTPM]":"4.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.1","Single Cell Type RNA - Endothelial cells [nTPM]":"4.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"9.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"26.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"55.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"159.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"30.5","Single Cell Type RNA - Langerhans cells [nTPM]":"9.9","Single Cell Type RNA - Late spermatids [nTPM]":"4.4","Single Cell Type RNA - Leydig cells [nTPM]":"9.3","Single Cell Type RNA - Macrophages [nTPM]":"31.0","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"396.3","Single Cell Type RNA - monocytes [nTPM]":"24.3","Single Cell Type RNA - Muller glia cells [nTPM]":"2.8","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"272.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"431.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"10.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - T-cells [nTPM]":"19.7","Single Cell Type RNA - Theca cells [nTPM]":"3.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"3.9"},{"Gene":"SLCO1B1","Gene synonym":["LST-1","OATP-C","OATP1B1","SLC21A6"],"Ensembl":"ENSG00000134538","Gene description":"Solute carrier organic anion transporter family member 1B1","Uniprot":["Q9Y6L6"],"Chromosome":"12","Position":"21131194-21239796","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"614","RNA tissue specific nTPM":{"liver":"537.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Hepatocytes":"83.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"96","RNA cancer specific FPKM":{"liver cancer":"52.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"1.1","NTERA-2":"1.3","RPMI-8226":"1.8","SuSa":"2.2"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050892","HPA073093"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA050892":"AB_2681265","HPA073093":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.8","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.4","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"537.2","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"0.7","Cell RNA - A549 [nTPM]":"0.5","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"1.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"1.8","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"2.2","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"83.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.2","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SLCO1B3","Gene synonym":["OATP1B3","OATP8","SLC21A8"],"Ensembl":"ENSG00000111700","Gene description":"Solute carrier organic anion transporter family member 1B3","Uniprot":["Q9NPD5"],"Chromosome":"12","Position":"20810702-20916911","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"16","RNA tissue specific nTPM":{"liver":"265.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"26","RNA single cell type specific nTPM":{"Hepatocytes":"203.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"liver cancer":"5.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"65.3","A549":"17.5","CAPAN-2":"12.6","GAMG":"13.6","HeLa":"14.2","PC-3":"17.3","U-2 OS":"14.7"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004943","HPA050892"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA004943":"AB_1854758","HPA050892":"AB_2681265"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-3"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"13.0","Tissue RNA - choroid plexus [nTPM]":"16.2","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"265.1","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.8","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"65.3","Cell RNA - A549 [nTPM]":"17.5","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"12.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"4.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"13.6","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.5","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"14.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"2.9","Cell RNA - hTERT-RPE1 [nTPM]":"1.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"17.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"14.7","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"1.3","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"4.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"203.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"7.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"SLCO2A1","Gene synonym":["MATR1","OATP2A1","PGT","SLC21A2"],"Ensembl":"ENSG00000174640","Gene description":"Solute carrier organic anion transporter family member 2A1","Uniprot":["Q92959"],"Chromosome":"3","Position":"133932701-134052184","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"123.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Distal enterocytes":"47.1","Endothelial cells":"65.2","Hepatic stellate cells":"146.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"EFO-21":"90.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013742"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA013742":"AB_2668877"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.69e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.24e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.25e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Tissue RNA - adipose tissue [nTPM]":"30.4","Tissue RNA - adrenal gland [nTPM]":"42.5","Tissue RNA - amygdala [nTPM]":"1.6","Tissue RNA - appendix [nTPM]":"16.8","Tissue RNA - basal ganglia [nTPM]":"1.6","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"18.1","Tissue RNA - cerebellum [nTPM]":"1.3","Tissue RNA - cerebral cortex [nTPM]":"2.7","Tissue RNA - cervix [nTPM]":"30.9","Tissue RNA - choroid plexus [nTPM]":"9.1","Tissue RNA - colon [nTPM]":"24.7","Tissue RNA - duodenum [nTPM]":"10.2","Tissue RNA - endometrium 1 [nTPM]":"46.3","Tissue RNA - epididymis [nTPM]":"6.1","Tissue RNA - esophagus [nTPM]":"18.8","Tissue RNA - fallopian tube [nTPM]":"28.3","Tissue RNA - gallbladder [nTPM]":"18.8","Tissue RNA - heart muscle [nTPM]":"26.4","Tissue RNA - hippocampal formation [nTPM]":"1.5","Tissue RNA - hypothalamus [nTPM]":"1.6","Tissue RNA - kidney [nTPM]":"52.8","Tissue RNA - liver [nTPM]":"2.4","Tissue RNA - lung [nTPM]":"123.7","Tissue RNA - lymph node [nTPM]":"9.2","Tissue RNA - medulla oblongata [nTPM]":"2.0","Tissue RNA - midbrain [nTPM]":"1.6","Tissue RNA - ovary [nTPM]":"5.2","Tissue RNA - pancreas [nTPM]":"20.8","Tissue RNA - parathyroid gland [nTPM]":"28.7","Tissue RNA - pituitary gland [nTPM]":"15.8","Tissue RNA - placenta [nTPM]":"23.4","Tissue RNA - pons [nTPM]":"2.2","Tissue RNA - prostate [nTPM]":"36.5","Tissue RNA - rectum [nTPM]":"18.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"20.8","Tissue RNA - seminal vesicle [nTPM]":"84.7","Tissue RNA - skeletal muscle [nTPM]":"2.1","Tissue RNA - skin 1 [nTPM]":"13.5","Tissue RNA - small intestine [nTPM]":"29.3","Tissue RNA - smooth muscle [nTPM]":"33.5","Tissue RNA - spinal cord [nTPM]":"1.9","Tissue RNA - spleen [nTPM]":"24.2","Tissue RNA - stomach 1 [nTPM]":"23.6","Tissue RNA - testis [nTPM]":"1.3","Tissue RNA - thalamus [nTPM]":"2.3","Tissue RNA - thymus [nTPM]":"8.4","Tissue RNA - thyroid gland [nTPM]":"89.3","Tissue RNA - tongue [nTPM]":"3.4","Tissue RNA - tonsil [nTPM]":"9.6","Tissue RNA - urinary bladder [nTPM]":"21.3","Tissue RNA - vagina [nTPM]":"20.3","Tissue RNA - white matter [nTPM]":"1.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"3.5","Cell RNA - BJ hTERT+ [nTPM]":"4.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"90.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.9","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"11.2","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"5.8","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"2.4","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"3.4","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"1.5","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.5","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.7","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"6.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"8.7","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"4.6","Cell RNA - SK-BR-3 [nTPM]":"1.5","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"3.7","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"22.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"4.5","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"2.4","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.6","Brain RNA - basal ganglia [nTPM]":"1.6","Brain RNA - cerebellum [nTPM]":"1.3","Brain RNA - cerebral cortex [nTPM]":"2.7","Brain RNA - hippocampal formation [nTPM]":"1.5","Brain RNA - hypothalamus [nTPM]":"1.6","Brain RNA - medulla oblongata [nTPM]":"2.0","Brain RNA - midbrain [nTPM]":"1.6","Brain RNA - pons [nTPM]":"2.2","Brain RNA - spinal cord [nTPM]":"1.9","Brain RNA - thalamus [nTPM]":"2.3","Brain RNA - white matter [nTPM]":"1.7","Single Cell Type RNA - Adipocytes [nTPM]":"19.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"1.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"47.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.8","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"65.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.0","Single Cell Type RNA - Fibroblasts [nTPM]":"8.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.6","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"146.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.2","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.0","Single Cell Type RNA - Paneth cells [nTPM]":"15.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"2.2"},{"Gene":"SLURP1","Gene synonym":["ANUP","ARS","ArsB","LY6-MT","LY6LS","MDM"],"Ensembl":"ENSG00000126233","Gene description":"Secreted LY6\/PLAUR domain containing 1","Uniprot":["P55000"],"Chromosome":"8","Position":"142740949-142742406","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted secreted proteins","Transporters"],"Biological process":null,"Molecular function":["Cytokine"],"Disease involvement":["Disease variant","Palmoplantar keratoderma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"esophagus":"1039.2","skin 1":"858.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"Squamous epithelial cells":"20.8","Suprabasal keratinocytes":"65.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"66.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"1.3","MCF7":"1.5","RT4":"1.1","T-47d":"2.6"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050967"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7700000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 61: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA050967":"AB_2681293"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.9","Tissue RNA - adrenal gland [nTPM]":"0.6","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"11.3","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"105.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"1039.2","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.5","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.6","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"70.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"1.4","Tissue RNA - skin 1 [nTPM]":"858.5","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.8","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.9","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"17.4","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"206.7","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"1.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.5","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"1.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"2.6","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"65.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"SMARCAD1","Gene synonym":["DKFZP762K2015","ETL1","KIAA1122"],"Ensembl":"ENSG00000163104","Gene description":"SWI\/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD\/H box 1","Uniprot":["Q9H4L7"],"Chromosome":"4","Position":"94207611-94291292","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["Chromatin regulator","DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Ectodermal dysplasia","Palmoplantar keratoderma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"86.5","Inhibitory neurons":"82.5","Oligodendrocyte precursor cells":"86.5","Oligodendrocytes":"99.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016737"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA016737":"AB_1857271"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.41e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.08e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.22e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-3"},"Tissue RNA - adipose tissue [nTPM]":"10.0","Tissue RNA - adrenal gland [nTPM]":"9.5","Tissue RNA - amygdala [nTPM]":"7.1","Tissue RNA - appendix [nTPM]":"11.2","Tissue RNA - basal ganglia [nTPM]":"7.8","Tissue RNA - bone marrow [nTPM]":"7.5","Tissue RNA - breast [nTPM]":"15.2","Tissue RNA - cerebellum [nTPM]":"12.0","Tissue RNA - cerebral cortex [nTPM]":"8.5","Tissue RNA - cervix [nTPM]":"10.6","Tissue RNA - choroid plexus [nTPM]":"7.5","Tissue RNA - colon [nTPM]":"9.4","Tissue RNA - duodenum [nTPM]":"9.7","Tissue RNA - endometrium 1 [nTPM]":"14.5","Tissue RNA - epididymis [nTPM]":"12.6","Tissue RNA - esophagus [nTPM]":"10.5","Tissue RNA - fallopian tube [nTPM]":"10.7","Tissue RNA - gallbladder [nTPM]":"10.3","Tissue RNA - heart muscle [nTPM]":"7.6","Tissue RNA - hippocampal formation [nTPM]":"7.3","Tissue RNA - hypothalamus [nTPM]":"8.6","Tissue RNA - kidney [nTPM]":"11.7","Tissue RNA - liver [nTPM]":"9.8","Tissue RNA - lung [nTPM]":"9.7","Tissue RNA - lymph node [nTPM]":"16.0","Tissue RNA - medulla oblongata [nTPM]":"7.2","Tissue RNA - midbrain [nTPM]":"7.4","Tissue RNA - ovary [nTPM]":"14.2","Tissue RNA - pancreas [nTPM]":"8.7","Tissue RNA - parathyroid gland [nTPM]":"11.7","Tissue RNA - pituitary gland [nTPM]":"11.0","Tissue RNA - placenta [nTPM]":"14.1","Tissue RNA - pons [nTPM]":"7.7","Tissue RNA - prostate [nTPM]":"11.1","Tissue RNA - rectum [nTPM]":"12.3","Tissue RNA - retina [nTPM]":"14.6","Tissue RNA - salivary gland [nTPM]":"8.9","Tissue RNA - seminal vesicle [nTPM]":"10.0","Tissue RNA - skeletal muscle [nTPM]":"7.3","Tissue RNA - skin 1 [nTPM]":"20.8","Tissue RNA - small intestine [nTPM]":"9.5","Tissue RNA - smooth muscle [nTPM]":"11.8","Tissue RNA - spinal cord [nTPM]":"7.7","Tissue RNA - spleen [nTPM]":"11.9","Tissue RNA - stomach 1 [nTPM]":"10.8","Tissue RNA - testis [nTPM]":"12.2","Tissue RNA - thalamus [nTPM]":"8.2","Tissue RNA - thymus [nTPM]":"18.6","Tissue RNA - thyroid gland [nTPM]":"15.0","Tissue RNA - tongue [nTPM]":"6.8","Tissue RNA - tonsil [nTPM]":"14.2","Tissue RNA - urinary bladder [nTPM]":"11.2","Tissue RNA - vagina [nTPM]":"9.7","Tissue RNA - white matter [nTPM]":"9.9","Cell RNA - A-431 [nTPM]":"15.0","Cell RNA - A549 [nTPM]":"18.6","Cell RNA - AF22 [nTPM]":"59.1","Cell RNA - AN3-CA [nTPM]":"38.1","Cell RNA - ASC diff [nTPM]":"16.5","Cell RNA - ASC TERT1 [nTPM]":"26.6","Cell RNA - BEWO [nTPM]":"30.1","Cell RNA - BJ [nTPM]":"26.8","Cell RNA - BJ hTERT+ [nTPM]":"24.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.3","Cell RNA - CACO-2 [nTPM]":"18.2","Cell RNA - CAPAN-2 [nTPM]":"23.7","Cell RNA - Daudi [nTPM]":"37.8","Cell RNA - EFO-21 [nTPM]":"17.7","Cell RNA - fHDF\/TERT166 [nTPM]":"23.1","Cell RNA - GAMG [nTPM]":"19.8","Cell RNA - HaCaT [nTPM]":"12.9","Cell RNA - HAP1 [nTPM]":"42.3","Cell RNA - HBEC3-KT [nTPM]":"22.4","Cell RNA - HBF TERT88 [nTPM]":"30.7","Cell RNA - HDLM-2 [nTPM]":"29.8","Cell RNA - HEK 293 [nTPM]":"18.7","Cell RNA - HEL [nTPM]":"27.5","Cell RNA - HeLa [nTPM]":"20.5","Cell RNA - Hep G2 [nTPM]":"27.2","Cell RNA - HHSteC [nTPM]":"24.4","Cell RNA - HL-60 [nTPM]":"41.2","Cell RNA - HMC-1 [nTPM]":"28.9","Cell RNA - HSkMC [nTPM]":"27.8","Cell RNA - hTCEpi [nTPM]":"17.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"27.3","Cell RNA - hTERT-HME1 [nTPM]":"34.9","Cell RNA - hTERT-RPE1 [nTPM]":"27.0","Cell RNA - HUVEC TERT2 [nTPM]":"33.7","Cell RNA - JURKAT [nTPM]":"33.3","Cell RNA - K-562 [nTPM]":"46.7","Cell RNA - Karpas-707 [nTPM]":"15.5","Cell RNA - LHCN-M2 [nTPM]":"32.4","Cell RNA - MCF7 [nTPM]":"12.3","Cell RNA - MOLT-4 [nTPM]":"69.1","Cell RNA - NB-4 [nTPM]":"21.3","Cell RNA - NTERA-2 [nTPM]":"40.1","Cell RNA - OE19 [nTPM]":"19.1","Cell RNA - PC-3 [nTPM]":"9.4","Cell RNA - REH [nTPM]":"40.1","Cell RNA - RH-30 [nTPM]":"33.6","Cell RNA - RPMI-8226 [nTPM]":"19.6","Cell RNA - RPTEC TERT1 [nTPM]":"24.6","Cell RNA - RT4 [nTPM]":"18.4","Cell RNA - SCLC-21H [nTPM]":"33.8","Cell RNA - SH-SY5Y [nTPM]":"49.9","Cell RNA - SiHa [nTPM]":"20.1","Cell RNA - SK-BR-3 [nTPM]":"32.8","Cell RNA - SK-MEL-30 [nTPM]":"28.6","Cell RNA - SuSa [nTPM]":"36.7","Cell RNA - T-47d [nTPM]":"17.1","Cell RNA - THP-1 [nTPM]":"26.9","Cell RNA - TIME [nTPM]":"32.3","Cell RNA - U-138 MG [nTPM]":"27.6","Cell RNA - U-2 OS [nTPM]":"29.9","Cell RNA - U-2197 [nTPM]":"17.1","Cell RNA - U-251 MG [nTPM]":"20.3","Cell RNA - U-266\/70 [nTPM]":"21.8","Cell RNA - U-266\/84 [nTPM]":"34.8","Cell RNA - U-698 [nTPM]":"45.1","Cell RNA - U-87 MG [nTPM]":"25.7","Cell RNA - U-937 [nTPM]":"21.2","Cell RNA - WM-115 [nTPM]":"34.8","Blood RNA - basophil [nTPM]":"2.7","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"2.3","Blood RNA - intermediate monocyte [nTPM]":"1.7","Blood RNA - MAIT T-cell [nTPM]":"2.5","Blood RNA - memory B-cell [nTPM]":"2.9","Blood RNA - memory CD4 T-cell [nTPM]":"2.6","Blood RNA - memory CD8 T-cell [nTPM]":"2.6","Blood RNA - myeloid DC [nTPM]":"2.4","Blood RNA - naive B-cell [nTPM]":"2.4","Blood RNA - naive CD4 T-cell [nTPM]":"2.8","Blood RNA - naive CD8 T-cell [nTPM]":"3.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"4.5","Blood RNA - non-classical monocyte [nTPM]":"1.7","Blood RNA - plasmacytoid DC [nTPM]":"2.1","Blood RNA - T-reg [nTPM]":"2.3","Blood RNA - total PBMC [nTPM]":"1.3","Brain RNA - amygdala [nTPM]":"7.1","Brain RNA - basal ganglia [nTPM]":"7.8","Brain RNA - cerebellum [nTPM]":"12.0","Brain RNA - cerebral cortex [nTPM]":"8.5","Brain RNA - hippocampal formation [nTPM]":"7.3","Brain RNA - hypothalamus [nTPM]":"8.6","Brain RNA - medulla oblongata [nTPM]":"7.2","Brain RNA - midbrain [nTPM]":"7.4","Brain RNA - pons [nTPM]":"7.7","Brain RNA - spinal cord [nTPM]":"7.7","Brain RNA - thalamus [nTPM]":"8.2","Brain RNA - white matter [nTPM]":"9.9","Single Cell Type RNA - Adipocytes [nTPM]":"19.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.3","Single Cell Type RNA - Astrocytes [nTPM]":"56.2","Single Cell Type RNA - B-cells [nTPM]":"16.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.6","Single Cell Type RNA - Bipolar cells [nTPM]":"20.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"24.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.5","Single Cell Type RNA - dendritic cells [nTPM]":"20.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"12.4","Single Cell Type RNA - Early spermatids [nTPM]":"2.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"32.3","Single Cell Type RNA - Endothelial cells [nTPM]":"17.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.0","Single Cell Type RNA - Erythroid cells [nTPM]":"25.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"86.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.8","Single Cell Type RNA - Fibroblasts [nTPM]":"19.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.9","Single Cell Type RNA - granulocytes [nTPM]":"24.0","Single Cell Type RNA - Granulosa cells [nTPM]":"29.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.2","Single Cell Type RNA - Hepatocytes [nTPM]":"13.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.8","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"82.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.9","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"14.6","Single Cell Type RNA - Langerhans cells [nTPM]":"5.4","Single Cell Type RNA - Late spermatids [nTPM]":"3.1","Single Cell Type RNA - Leydig cells [nTPM]":"14.3","Single Cell Type RNA - Macrophages [nTPM]":"13.7","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"47.8","Single Cell Type RNA - monocytes [nTPM]":"12.6","Single Cell Type RNA - Muller glia cells [nTPM]":"8.1","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"86.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"99.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.0","Single Cell Type RNA - Paneth cells [nTPM]":"6.3","Single Cell Type RNA - Peritubular cells [nTPM]":"18.4","Single Cell Type RNA - Plasma cells [nTPM]":"16.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"26.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.2","Single Cell Type RNA - Spermatocytes [nTPM]":"25.9","Single Cell Type RNA - Spermatogonia [nTPM]":"34.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.6","Single Cell Type RNA - T-cells [nTPM]":"17.3","Single Cell Type RNA - Theca cells [nTPM]":"26.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.6","Single Cell Type RNA - Urothelial cells [nTPM]":"5.8"},{"Gene":"SMPD1","Gene synonym":["ASM"],"Ensembl":"ENSG00000166311","Gene description":"Sphingomyelin phosphodiesterase 1","Uniprot":["P17405"],"Chromosome":"11","Position":"6390440-6394998","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant","Neurodegeneration","Niemann-Pick disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"131.3","Late spermatids":"200.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"139.1","fHDF\/TERT166":"144.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2700000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.72e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.47e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.57e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Tissue RNA - adipose tissue [nTPM]":"21.8","Tissue RNA - adrenal gland [nTPM]":"36.5","Tissue RNA - amygdala [nTPM]":"38.8","Tissue RNA - appendix [nTPM]":"13.9","Tissue RNA - basal ganglia [nTPM]":"44.7","Tissue RNA - bone marrow [nTPM]":"7.3","Tissue RNA - breast [nTPM]":"20.1","Tissue RNA - cerebellum [nTPM]":"45.1","Tissue RNA - cerebral cortex [nTPM]":"43.0","Tissue RNA - cervix [nTPM]":"21.2","Tissue RNA - choroid plexus [nTPM]":"33.9","Tissue RNA - colon [nTPM]":"25.3","Tissue RNA - duodenum [nTPM]":"16.8","Tissue RNA - endometrium 1 [nTPM]":"20.9","Tissue RNA - epididymis [nTPM]":"14.4","Tissue RNA - esophagus [nTPM]":"20.6","Tissue RNA - fallopian tube [nTPM]":"14.6","Tissue RNA - gallbladder [nTPM]":"21.5","Tissue RNA - heart muscle [nTPM]":"55.8","Tissue RNA - hippocampal formation [nTPM]":"39.1","Tissue RNA - hypothalamus [nTPM]":"43.0","Tissue RNA - kidney [nTPM]":"73.7","Tissue RNA - liver [nTPM]":"95.3","Tissue RNA - lung [nTPM]":"31.3","Tissue RNA - lymph node [nTPM]":"14.6","Tissue RNA - medulla oblongata [nTPM]":"42.7","Tissue RNA - midbrain [nTPM]":"42.6","Tissue RNA - ovary [nTPM]":"17.9","Tissue RNA - pancreas [nTPM]":"32.8","Tissue RNA - parathyroid gland [nTPM]":"34.2","Tissue RNA - pituitary gland [nTPM]":"41.9","Tissue RNA - placenta [nTPM]":"21.6","Tissue RNA - pons [nTPM]":"43.3","Tissue RNA - prostate [nTPM]":"29.4","Tissue RNA - rectum [nTPM]":"14.9","Tissue RNA - retina [nTPM]":"8.5","Tissue RNA - salivary gland [nTPM]":"29.0","Tissue RNA - seminal vesicle [nTPM]":"20.0","Tissue RNA - skeletal muscle [nTPM]":"37.9","Tissue RNA - skin 1 [nTPM]":"37.9","Tissue RNA - small intestine [nTPM]":"23.8","Tissue RNA - smooth muscle [nTPM]":"17.6","Tissue RNA - spinal cord [nTPM]":"40.9","Tissue RNA - spleen [nTPM]":"21.1","Tissue RNA - stomach 1 [nTPM]":"25.4","Tissue RNA - testis [nTPM]":"14.0","Tissue RNA - thalamus [nTPM]":"47.5","Tissue RNA - thymus [nTPM]":"17.8","Tissue RNA - thyroid gland [nTPM]":"34.0","Tissue RNA - tongue [nTPM]":"29.4","Tissue RNA - tonsil [nTPM]":"11.0","Tissue RNA - urinary bladder [nTPM]":"23.6","Tissue RNA - vagina [nTPM]":"21.0","Tissue RNA - white matter [nTPM]":"46.8","Cell RNA - A-431 [nTPM]":"16.4","Cell RNA - A549 [nTPM]":"13.1","Cell RNA - AF22 [nTPM]":"10.1","Cell RNA - AN3-CA [nTPM]":"26.5","Cell RNA - ASC diff [nTPM]":"139.1","Cell RNA - ASC TERT1 [nTPM]":"72.2","Cell RNA - BEWO [nTPM]":"17.1","Cell RNA - BJ [nTPM]":"60.4","Cell RNA - BJ hTERT+ [nTPM]":"95.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"27.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"33.0","Cell RNA - CACO-2 [nTPM]":"22.0","Cell RNA - CAPAN-2 [nTPM]":"11.9","Cell RNA - Daudi [nTPM]":"4.7","Cell RNA - EFO-21 [nTPM]":"27.4","Cell RNA - fHDF\/TERT166 [nTPM]":"144.0","Cell RNA - GAMG [nTPM]":"59.3","Cell RNA - HaCaT [nTPM]":"7.4","Cell RNA - HAP1 [nTPM]":"8.4","Cell RNA - HBEC3-KT [nTPM]":"12.7","Cell RNA - HBF TERT88 [nTPM]":"13.0","Cell RNA - HDLM-2 [nTPM]":"21.0","Cell RNA - HEK 293 [nTPM]":"9.6","Cell RNA - HEL [nTPM]":"5.1","Cell RNA - HeLa [nTPM]":"19.5","Cell RNA - Hep G2 [nTPM]":"6.0","Cell RNA - HHSteC [nTPM]":"62.3","Cell RNA - HL-60 [nTPM]":"3.7","Cell RNA - HMC-1 [nTPM]":"37.4","Cell RNA - HSkMC [nTPM]":"96.0","Cell RNA - hTCEpi [nTPM]":"23.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.9","Cell RNA - hTERT-HME1 [nTPM]":"17.7","Cell RNA - hTERT-RPE1 [nTPM]":"100.9","Cell RNA - HUVEC TERT2 [nTPM]":"61.6","Cell RNA - JURKAT [nTPM]":"1.7","Cell RNA - K-562 [nTPM]":"9.1","Cell RNA - Karpas-707 [nTPM]":"30.5","Cell RNA - LHCN-M2 [nTPM]":"58.9","Cell RNA - MCF7 [nTPM]":"17.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"6.5","Cell RNA - NTERA-2 [nTPM]":"3.9","Cell RNA - OE19 [nTPM]":"23.2","Cell RNA - PC-3 [nTPM]":"22.3","Cell RNA - REH [nTPM]":"1.2","Cell RNA - RH-30 [nTPM]":"5.5","Cell RNA - RPMI-8226 [nTPM]":"7.0","Cell RNA - RPTEC TERT1 [nTPM]":"23.9","Cell RNA - RT4 [nTPM]":"6.2","Cell RNA - SCLC-21H [nTPM]":"17.0","Cell RNA - SH-SY5Y [nTPM]":"9.7","Cell RNA - SiHa [nTPM]":"27.6","Cell RNA - SK-BR-3 [nTPM]":"19.5","Cell RNA - SK-MEL-30 [nTPM]":"38.5","Cell RNA - SuSa [nTPM]":"12.9","Cell RNA - T-47d [nTPM]":"7.3","Cell RNA - THP-1 [nTPM]":"7.0","Cell RNA - TIME [nTPM]":"53.9","Cell RNA - U-138 MG [nTPM]":"103.0","Cell RNA - U-2 OS [nTPM]":"10.9","Cell RNA - U-2197 [nTPM]":"59.1","Cell RNA - U-251 MG [nTPM]":"15.4","Cell RNA - U-266\/70 [nTPM]":"37.6","Cell RNA - U-266\/84 [nTPM]":"44.0","Cell RNA - U-698 [nTPM]":"3.5","Cell RNA - U-87 MG [nTPM]":"93.7","Cell RNA - U-937 [nTPM]":"10.8","Cell RNA - WM-115 [nTPM]":"47.1","Blood RNA - basophil [nTPM]":"1.9","Blood RNA - classical monocyte [nTPM]":"2.5","Blood RNA - eosinophil [nTPM]":"3.4","Blood RNA - gdT-cell [nTPM]":"6.4","Blood RNA - intermediate monocyte [nTPM]":"2.1","Blood RNA - MAIT T-cell [nTPM]":"5.0","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"5.5","Blood RNA - memory CD8 T-cell [nTPM]":"5.0","Blood RNA - myeloid DC [nTPM]":"1.3","Blood RNA - naive B-cell [nTPM]":"3.1","Blood RNA - naive CD4 T-cell [nTPM]":"10.0","Blood RNA - naive CD8 T-cell [nTPM]":"10.1","Blood RNA - neutrophil [nTPM]":"2.5","Blood RNA - NK-cell [nTPM]":"6.6","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"1.7","Blood RNA - T-reg [nTPM]":"4.7","Blood RNA - total PBMC [nTPM]":"3.2","Brain RNA - amygdala [nTPM]":"38.8","Brain RNA - basal ganglia [nTPM]":"44.7","Brain RNA - cerebellum [nTPM]":"45.1","Brain RNA - cerebral cortex [nTPM]":"43.0","Brain RNA - hippocampal formation [nTPM]":"39.1","Brain RNA - hypothalamus [nTPM]":"43.0","Brain RNA - medulla oblongata [nTPM]":"42.7","Brain RNA - midbrain [nTPM]":"42.6","Brain RNA - pons [nTPM]":"43.3","Brain RNA - spinal cord [nTPM]":"40.9","Brain RNA - thalamus [nTPM]":"47.5","Brain RNA - white matter [nTPM]":"46.8","Single Cell Type RNA - Adipocytes [nTPM]":"14.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.4","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"12.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"12.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"37.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"12.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"38.8","Single Cell Type RNA - dendritic cells [nTPM]":"11.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"131.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"53.4","Single Cell Type RNA - Early spermatids [nTPM]":"50.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.0","Single Cell Type RNA - Endothelial cells [nTPM]":"18.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"23.8","Single Cell Type RNA - Erythroid cells [nTPM]":"9.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"38.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.4","Single Cell Type RNA - Fibroblasts [nTPM]":"31.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.0","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"9.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.7","Single Cell Type RNA - Hepatocytes [nTPM]":"88.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"34.1","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.3","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"15.5","Single Cell Type RNA - Langerhans cells [nTPM]":"6.2","Single Cell Type RNA - Late spermatids [nTPM]":"200.7","Single Cell Type RNA - Leydig cells [nTPM]":"11.5","Single Cell Type RNA - Macrophages [nTPM]":"15.8","Single Cell Type RNA - Melanocytes [nTPM]":"55.2","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"7.8","Single Cell Type RNA - Muller glia cells [nTPM]":"16.4","Single Cell Type RNA - NK-cells [nTPM]":"36.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"24.7","Single Cell Type RNA - Paneth cells [nTPM]":"83.1","Single Cell Type RNA - Peritubular cells [nTPM]":"13.5","Single Cell Type RNA - Plasma cells [nTPM]":"23.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"26.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"51.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"75.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.4","Single Cell Type RNA - Spermatogonia [nTPM]":"3.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"34.3","Single Cell Type RNA - T-cells [nTPM]":"23.3","Single Cell Type RNA - Theca cells [nTPM]":"10.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.0","Single Cell Type RNA - Urothelial cells [nTPM]":"15.4"},{"Gene":"SMPD4","Gene synonym":["FLJ20297","FLJ20756","KIAA1418","NET13","nSMase-3","NSMASE3"],"Ensembl":"ENSG00000136699","Gene description":"Sphingomyelin phosphodiesterase 4","Uniprot":["Q9NXE4"],"Chromosome":"2","Position":"130151392-130182750","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046279","HPA049426"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA046279":"AB_2679611","HPA049426":"AB_2680762"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.61e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.47e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.37e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.73e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.16e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.9","Tissue RNA - adrenal gland [nTPM]":"10.8","Tissue RNA - amygdala [nTPM]":"4.2","Tissue RNA - appendix [nTPM]":"11.1","Tissue RNA - basal ganglia [nTPM]":"4.9","Tissue RNA - bone marrow [nTPM]":"25.4","Tissue RNA - breast [nTPM]":"10.9","Tissue RNA - cerebellum [nTPM]":"5.3","Tissue RNA - cerebral cortex [nTPM]":"6.2","Tissue RNA - cervix [nTPM]":"15.5","Tissue RNA - choroid plexus [nTPM]":"3.1","Tissue RNA - colon [nTPM]":"12.1","Tissue RNA - duodenum [nTPM]":"9.5","Tissue RNA - endometrium 1 [nTPM]":"15.5","Tissue RNA - epididymis [nTPM]":"5.0","Tissue RNA - esophagus [nTPM]":"13.8","Tissue RNA - fallopian tube [nTPM]":"15.9","Tissue RNA - gallbladder [nTPM]":"9.2","Tissue RNA - heart muscle [nTPM]":"11.7","Tissue RNA - hippocampal formation [nTPM]":"4.0","Tissue RNA - hypothalamus [nTPM]":"7.0","Tissue RNA - kidney [nTPM]":"8.6","Tissue RNA - liver [nTPM]":"9.2","Tissue RNA - lung [nTPM]":"10.6","Tissue RNA - lymph node [nTPM]":"15.7","Tissue RNA - medulla oblongata [nTPM]":"7.5","Tissue RNA - midbrain [nTPM]":"5.0","Tissue RNA - ovary [nTPM]":"14.6","Tissue RNA - pancreas [nTPM]":"13.3","Tissue RNA - parathyroid gland [nTPM]":"15.2","Tissue RNA - pituitary gland [nTPM]":"22.7","Tissue RNA - placenta [nTPM]":"14.9","Tissue RNA - pons [nTPM]":"6.3","Tissue RNA - prostate [nTPM]":"11.8","Tissue RNA - rectum [nTPM]":"11.1","Tissue RNA - retina [nTPM]":"4.7","Tissue RNA - salivary gland [nTPM]":"12.9","Tissue RNA - seminal vesicle [nTPM]":"11.7","Tissue RNA - skeletal muscle [nTPM]":"13.3","Tissue RNA - skin 1 [nTPM]":"13.5","Tissue RNA - small intestine [nTPM]":"11.5","Tissue RNA - smooth muscle [nTPM]":"12.9","Tissue RNA - spinal cord [nTPM]":"2.4","Tissue RNA - spleen [nTPM]":"11.2","Tissue RNA - stomach 1 [nTPM]":"10.3","Tissue RNA - testis [nTPM]":"17.7","Tissue RNA - thalamus [nTPM]":"6.0","Tissue RNA - thymus [nTPM]":"19.8","Tissue RNA - thyroid gland [nTPM]":"16.0","Tissue RNA - tongue [nTPM]":"12.0","Tissue RNA - tonsil [nTPM]":"15.7","Tissue RNA - urinary bladder [nTPM]":"11.8","Tissue RNA - vagina [nTPM]":"12.3","Tissue RNA - white matter [nTPM]":"10.0","Cell RNA - A-431 [nTPM]":"89.1","Cell RNA - A549 [nTPM]":"41.5","Cell RNA - AF22 [nTPM]":"46.2","Cell RNA - AN3-CA [nTPM]":"39.2","Cell RNA - ASC diff [nTPM]":"29.1","Cell RNA - ASC TERT1 [nTPM]":"21.8","Cell RNA - BEWO [nTPM]":"58.7","Cell RNA - BJ [nTPM]":"41.5","Cell RNA - BJ hTERT+ [nTPM]":"42.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"76.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"62.8","Cell RNA - CACO-2 [nTPM]":"119.2","Cell RNA - CAPAN-2 [nTPM]":"47.0","Cell RNA - Daudi [nTPM]":"56.2","Cell RNA - EFO-21 [nTPM]":"41.2","Cell RNA - fHDF\/TERT166 [nTPM]":"49.9","Cell RNA - GAMG [nTPM]":"36.3","Cell RNA - HaCaT [nTPM]":"43.8","Cell RNA - HAP1 [nTPM]":"64.0","Cell RNA - HBEC3-KT [nTPM]":"64.4","Cell RNA - HBF TERT88 [nTPM]":"40.4","Cell RNA - HDLM-2 [nTPM]":"72.7","Cell RNA - HEK 293 [nTPM]":"61.2","Cell RNA - HEL [nTPM]":"60.5","Cell RNA - HeLa [nTPM]":"36.2","Cell RNA - Hep G2 [nTPM]":"90.1","Cell RNA - HHSteC [nTPM]":"31.2","Cell RNA - HL-60 [nTPM]":"68.5","Cell RNA - HMC-1 [nTPM]":"34.7","Cell RNA - HSkMC [nTPM]":"25.6","Cell RNA - hTCEpi [nTPM]":"39.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"77.0","Cell RNA - hTERT-HME1 [nTPM]":"27.2","Cell RNA - hTERT-RPE1 [nTPM]":"21.1","Cell RNA - HUVEC TERT2 [nTPM]":"44.9","Cell RNA - JURKAT [nTPM]":"51.4","Cell RNA - K-562 [nTPM]":"82.2","Cell RNA - Karpas-707 [nTPM]":"40.8","Cell RNA - LHCN-M2 [nTPM]":"40.7","Cell RNA - MCF7 [nTPM]":"44.3","Cell RNA - MOLT-4 [nTPM]":"72.2","Cell RNA - NB-4 [nTPM]":"32.0","Cell RNA - NTERA-2 [nTPM]":"77.0","Cell RNA - OE19 [nTPM]":"40.1","Cell RNA - PC-3 [nTPM]":"56.4","Cell RNA - REH [nTPM]":"74.3","Cell RNA - RH-30 [nTPM]":"44.2","Cell RNA - RPMI-8226 [nTPM]":"59.0","Cell RNA - RPTEC TERT1 [nTPM]":"27.0","Cell RNA - RT4 [nTPM]":"38.6","Cell RNA - SCLC-21H [nTPM]":"66.8","Cell RNA - SH-SY5Y [nTPM]":"36.3","Cell RNA - SiHa [nTPM]":"42.8","Cell RNA - SK-BR-3 [nTPM]":"54.5","Cell RNA - SK-MEL-30 [nTPM]":"22.7","Cell RNA - SuSa [nTPM]":"24.9","Cell RNA - T-47d [nTPM]":"37.8","Cell RNA - THP-1 [nTPM]":"34.8","Cell RNA - TIME [nTPM]":"32.8","Cell RNA - U-138 MG [nTPM]":"57.0","Cell RNA - U-2 OS [nTPM]":"49.3","Cell RNA - U-2197 [nTPM]":"33.0","Cell RNA - U-251 MG [nTPM]":"49.4","Cell RNA - U-266\/70 [nTPM]":"34.3","Cell RNA - U-266\/84 [nTPM]":"44.0","Cell RNA - U-698 [nTPM]":"79.2","Cell RNA - U-87 MG [nTPM]":"51.4","Cell RNA - U-937 [nTPM]":"38.7","Cell RNA - WM-115 [nTPM]":"44.0","Blood RNA - basophil [nTPM]":"1.8","Blood RNA - classical monocyte [nTPM]":"9.2","Blood RNA - eosinophil [nTPM]":"14.8","Blood RNA - gdT-cell [nTPM]":"12.9","Blood RNA - intermediate monocyte [nTPM]":"11.2","Blood RNA - MAIT T-cell [nTPM]":"14.3","Blood RNA - memory B-cell [nTPM]":"8.9","Blood RNA - memory CD4 T-cell [nTPM]":"9.6","Blood RNA - memory CD8 T-cell [nTPM]":"11.6","Blood RNA - myeloid DC [nTPM]":"9.6","Blood RNA - naive B-cell [nTPM]":"9.1","Blood RNA - naive CD4 T-cell [nTPM]":"9.0","Blood RNA - naive CD8 T-cell [nTPM]":"10.5","Blood RNA - neutrophil [nTPM]":"4.3","Blood RNA - NK-cell [nTPM]":"12.1","Blood RNA - non-classical monocyte [nTPM]":"8.1","Blood RNA - plasmacytoid DC [nTPM]":"6.0","Blood RNA - T-reg [nTPM]":"9.2","Blood RNA - total PBMC [nTPM]":"10.4","Brain RNA - amygdala [nTPM]":"4.2","Brain RNA - basal ganglia [nTPM]":"4.9","Brain RNA - cerebellum [nTPM]":"5.3","Brain RNA - cerebral cortex [nTPM]":"6.2","Brain RNA - hippocampal formation [nTPM]":"4.0","Brain RNA - hypothalamus [nTPM]":"7.0","Brain RNA - medulla oblongata [nTPM]":"7.5","Brain RNA - midbrain [nTPM]":"5.0","Brain RNA - pons [nTPM]":"6.3","Brain RNA - spinal cord [nTPM]":"2.4","Brain RNA - thalamus [nTPM]":"6.0","Brain RNA - white matter [nTPM]":"10.0","Single Cell Type RNA - Adipocytes [nTPM]":"17.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.3","Single Cell Type RNA - Astrocytes [nTPM]":"4.9","Single Cell Type RNA - B-cells [nTPM]":"20.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.0","Single Cell Type RNA - Bipolar cells [nTPM]":"19.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"8.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.8","Single Cell Type RNA - dendritic cells [nTPM]":"16.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"9.2","Single Cell Type RNA - Early spermatids [nTPM]":"22.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.7","Single Cell Type RNA - Endothelial cells [nTPM]":"12.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"21.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.5","Single Cell Type RNA - Fibroblasts [nTPM]":"12.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.3","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"29.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.4","Single Cell Type RNA - Hepatocytes [nTPM]":"17.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.1","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.8","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"13.2","Single Cell Type RNA - Langerhans cells [nTPM]":"7.7","Single Cell Type RNA - Late spermatids [nTPM]":"41.7","Single Cell Type RNA - Leydig cells [nTPM]":"14.6","Single Cell Type RNA - Macrophages [nTPM]":"10.2","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"8.8","Single Cell Type RNA - Muller glia cells [nTPM]":"9.9","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.8","Single Cell Type RNA - Paneth cells [nTPM]":"10.5","Single Cell Type RNA - Peritubular cells [nTPM]":"18.4","Single Cell Type RNA - Plasma cells [nTPM]":"27.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.8","Single Cell Type RNA - Spermatocytes [nTPM]":"25.0","Single Cell Type RNA - Spermatogonia [nTPM]":"25.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.6","Single Cell Type RNA - T-cells [nTPM]":"15.6","Single Cell Type RNA - Theca cells [nTPM]":"16.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.2","Single Cell Type RNA - Urothelial cells [nTPM]":"9.6"},{"Gene":"SNCA","Gene synonym":["NACP","PARK1","PARK4","PD1"],"Ensembl":"ENSG00000145335","Gene description":"Synuclein alpha","Uniprot":["P37840"],"Chromosome":"4","Position":"89700345-89838315","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Alzheimer disease","Disease variant","Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"bone marrow":"273.6","brain":"128.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"1225.0","Excitatory neurons":"251.5","Melanocytes":"352.2","Oligodendrocytes":"195.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"melanoma":"37.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"102.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"102.9","granulocytes":"51.5","monocytes":"66.9"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"221.5","HUVEC TERT2":"269.8","RT4":"137.3","SK-MEL-30":"271.6","TIME":"311.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005459","CAB010877"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"28000000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB010877":"AB_261518","HPA005459":"AB_2667324"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-3"},"Tissue RNA - adipose tissue [nTPM]":"16.0","Tissue RNA - adrenal gland [nTPM]":"9.9","Tissue RNA - amygdala [nTPM]":"91.5","Tissue RNA - appendix [nTPM]":"10.0","Tissue RNA - basal ganglia [nTPM]":"112.2","Tissue RNA - bone marrow [nTPM]":"273.6","Tissue RNA - breast [nTPM]":"7.8","Tissue RNA - cerebellum [nTPM]":"47.2","Tissue RNA - cerebral cortex [nTPM]":"128.2","Tissue RNA - cervix [nTPM]":"26.1","Tissue RNA - choroid plexus [nTPM]":"16.1","Tissue RNA - colon [nTPM]":"28.5","Tissue RNA - duodenum [nTPM]":"3.3","Tissue RNA - endometrium 1 [nTPM]":"34.3","Tissue RNA - epididymis [nTPM]":"3.4","Tissue RNA - esophagus [nTPM]":"8.5","Tissue RNA - fallopian tube [nTPM]":"11.2","Tissue RNA - gallbladder [nTPM]":"5.4","Tissue RNA - heart muscle [nTPM]":"20.9","Tissue RNA - hippocampal formation [nTPM]":"115.2","Tissue RNA - hypothalamus [nTPM]":"69.1","Tissue RNA - kidney [nTPM]":"12.4","Tissue RNA - liver [nTPM]":"2.9","Tissue RNA - lung [nTPM]":"16.6","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"97.5","Tissue RNA - midbrain [nTPM]":"88.3","Tissue RNA - ovary [nTPM]":"29.3","Tissue RNA - pancreas [nTPM]":"2.2","Tissue RNA - parathyroid gland [nTPM]":"1.1","Tissue RNA - pituitary gland [nTPM]":"28.7","Tissue RNA - placenta [nTPM]":"28.3","Tissue RNA - pons [nTPM]":"89.9","Tissue RNA - prostate [nTPM]":"17.3","Tissue RNA - rectum [nTPM]":"6.9","Tissue RNA - retina [nTPM]":"20.3","Tissue RNA - salivary gland [nTPM]":"15.9","Tissue RNA - seminal vesicle [nTPM]":"9.7","Tissue RNA - skeletal muscle [nTPM]":"1.2","Tissue RNA - skin 1 [nTPM]":"16.4","Tissue RNA - small intestine [nTPM]":"8.6","Tissue RNA - smooth muscle [nTPM]":"33.3","Tissue RNA - spinal cord [nTPM]":"36.0","Tissue RNA - spleen [nTPM]":"15.2","Tissue RNA - stomach 1 [nTPM]":"6.4","Tissue RNA - testis [nTPM]":"3.2","Tissue RNA - thalamus [nTPM]":"76.2","Tissue RNA - thymus [nTPM]":"5.3","Tissue RNA - thyroid gland [nTPM]":"10.2","Tissue RNA - tongue [nTPM]":"8.5","Tissue RNA - tonsil [nTPM]":"4.8","Tissue RNA - urinary bladder [nTPM]":"9.3","Tissue RNA - vagina [nTPM]":"23.2","Tissue RNA - white matter [nTPM]":"107.0","Cell RNA - A-431 [nTPM]":"0.5","Cell RNA - A549 [nTPM]":"1.0","Cell RNA - AF22 [nTPM]":"40.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.7","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.6","Cell RNA - BJ [nTPM]":"0.4","Cell RNA - BJ hTERT+ [nTPM]":"44.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"12.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"9.3","Cell RNA - HAP1 [nTPM]":"53.6","Cell RNA - HBEC3-KT [nTPM]":"97.7","Cell RNA - HBF TERT88 [nTPM]":"1.5","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"22.6","Cell RNA - HEL [nTPM]":"221.5","Cell RNA - HeLa [nTPM]":"115.4","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"84.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.4","Cell RNA - HSkMC [nTPM]":"2.1","Cell RNA - hTCEpi [nTPM]":"38.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"109.5","Cell RNA - hTERT-RPE1 [nTPM]":"117.3","Cell RNA - HUVEC TERT2 [nTPM]":"269.8","Cell RNA - JURKAT [nTPM]":"2.2","Cell RNA - K-562 [nTPM]":"2.0","Cell RNA - Karpas-707 [nTPM]":"0.6","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"2.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"10.6","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"4.8","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"15.8","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.3","Cell RNA - RT4 [nTPM]":"137.3","Cell RNA - SCLC-21H [nTPM]":"23.2","Cell RNA - SH-SY5Y [nTPM]":"15.6","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"271.6","Cell RNA - SuSa [nTPM]":"29.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"311.4","Cell RNA - U-138 MG [nTPM]":"1.3","Cell RNA - U-2 OS [nTPM]":"8.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.8","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"8.8","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"87.4","Blood RNA - basophil [nTPM]":"51.5","Blood RNA - classical monocyte [nTPM]":"66.9","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"27.7","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"4.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.9","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"84.6","Blood RNA - naive B-cell [nTPM]":"1.7","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"11.1","Blood RNA - NK-cell [nTPM]":"17.3","Blood RNA - non-classical monocyte [nTPM]":"8.2","Blood RNA - plasmacytoid DC [nTPM]":"102.9","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"63.7","Brain RNA - amygdala [nTPM]":"91.5","Brain RNA - basal ganglia [nTPM]":"112.2","Brain RNA - cerebellum [nTPM]":"47.2","Brain RNA - cerebral cortex [nTPM]":"128.2","Brain RNA - hippocampal formation [nTPM]":"115.2","Brain RNA - hypothalamus [nTPM]":"69.1","Brain RNA - medulla oblongata [nTPM]":"97.5","Brain RNA - midbrain [nTPM]":"88.3","Brain RNA - pons [nTPM]":"89.9","Brain RNA - spinal cord [nTPM]":"36.0","Brain RNA - thalamus [nTPM]":"76.2","Brain RNA - white matter [nTPM]":"107.0","Single Cell Type RNA - Adipocytes [nTPM]":"1.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"40.1","Single Cell Type RNA - B-cells [nTPM]":"2.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"76.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"173.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"101.3","Single Cell Type RNA - Bipolar cells [nTPM]":"10.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"21.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.1","Single Cell Type RNA - dendritic cells [nTPM]":"10.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.1","Single Cell Type RNA - Endothelial cells [nTPM]":"19.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"1225.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"251.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.9","Single Cell Type RNA - Fibroblasts [nTPM]":"32.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"23.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"0.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"62.3","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"53.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"44.7","Single Cell Type RNA - Kupffer cells [nTPM]":"17.2","Single Cell Type RNA - Langerhans cells [nTPM]":"64.2","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"100.7","Single Cell Type RNA - Melanocytes [nTPM]":"352.2","Single Cell Type RNA - Microglial cells [nTPM]":"76.8","Single Cell Type RNA - monocytes [nTPM]":"24.4","Single Cell Type RNA - Muller glia cells [nTPM]":"19.4","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"95.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"195.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.4","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.3","Single Cell Type RNA - Spermatocytes [nTPM]":"19.6","Single Cell Type RNA - Spermatogonia [nTPM]":"16.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - T-cells [nTPM]":"3.8","Single Cell Type RNA - Theca cells [nTPM]":"43.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"3.4"},{"Gene":"SNRNP200","Gene synonym":["ASCC3L1","BRR2","HELIC2","KIAA0788","RP33","U5-200KD"],"Ensembl":"ENSG00000144028","Gene description":"Small nuclear ribonucleoprotein U5 subunit 200","Uniprot":["O75643"],"Chromosome":"2","Position":"96274338-96321271","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":["Helicase","Hydrolase"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029321"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"78000","Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA029321":"AB_10604096"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.89e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Tissue RNA - adipose tissue [nTPM]":"26.5","Tissue RNA - adrenal gland [nTPM]":"21.8","Tissue RNA - amygdala [nTPM]":"11.2","Tissue RNA - appendix [nTPM]":"38.1","Tissue RNA - basal ganglia [nTPM]":"11.3","Tissue RNA - bone marrow [nTPM]":"58.8","Tissue RNA - breast [nTPM]":"38.6","Tissue RNA - cerebellum [nTPM]":"16.9","Tissue RNA - cerebral cortex [nTPM]":"12.1","Tissue RNA - cervix [nTPM]":"31.9","Tissue RNA - choroid plexus [nTPM]":"25.5","Tissue RNA - colon [nTPM]":"29.6","Tissue RNA - duodenum [nTPM]":"29.4","Tissue RNA - endometrium 1 [nTPM]":"41.0","Tissue RNA - epididymis [nTPM]":"20.2","Tissue RNA - esophagus [nTPM]":"29.5","Tissue RNA - fallopian tube [nTPM]":"39.8","Tissue RNA - gallbladder [nTPM]":"25.8","Tissue RNA - heart muscle [nTPM]":"26.9","Tissue RNA - hippocampal formation [nTPM]":"9.9","Tissue RNA - hypothalamus [nTPM]":"11.1","Tissue RNA - kidney [nTPM]":"28.8","Tissue RNA - liver [nTPM]":"29.3","Tissue RNA - lung [nTPM]":"29.3","Tissue RNA - lymph node [nTPM]":"43.2","Tissue RNA - medulla oblongata [nTPM]":"13.1","Tissue RNA - midbrain [nTPM]":"10.3","Tissue RNA - ovary [nTPM]":"53.2","Tissue RNA - pancreas [nTPM]":"34.3","Tissue RNA - parathyroid gland [nTPM]":"52.4","Tissue RNA - pituitary gland [nTPM]":"19.7","Tissue RNA - placenta [nTPM]":"39.2","Tissue RNA - pons [nTPM]":"12.0","Tissue RNA - prostate [nTPM]":"31.6","Tissue RNA - rectum [nTPM]":"34.6","Tissue RNA - retina [nTPM]":"67.6","Tissue RNA - salivary gland [nTPM]":"35.1","Tissue RNA - seminal vesicle [nTPM]":"33.0","Tissue RNA - skeletal muscle [nTPM]":"47.4","Tissue RNA - skin 1 [nTPM]":"30.8","Tissue RNA - small intestine [nTPM]":"30.3","Tissue RNA - smooth muscle [nTPM]":"38.5","Tissue RNA - spinal cord [nTPM]":"12.2","Tissue RNA - spleen [nTPM]":"36.5","Tissue RNA - stomach 1 [nTPM]":"30.6","Tissue RNA - testis [nTPM]":"40.4","Tissue RNA - thalamus [nTPM]":"9.8","Tissue RNA - thymus [nTPM]":"73.5","Tissue RNA - thyroid gland [nTPM]":"37.4","Tissue RNA - tongue [nTPM]":"38.7","Tissue RNA - tonsil [nTPM]":"52.3","Tissue RNA - urinary bladder [nTPM]":"30.1","Tissue RNA - vagina [nTPM]":"21.6","Tissue RNA - white matter [nTPM]":"14.6","Cell RNA - A-431 [nTPM]":"97.8","Cell RNA - A549 [nTPM]":"107.7","Cell RNA - AF22 [nTPM]":"144.1","Cell RNA - AN3-CA [nTPM]":"106.1","Cell RNA - ASC diff [nTPM]":"63.1","Cell RNA - ASC TERT1 [nTPM]":"57.1","Cell RNA - BEWO [nTPM]":"131.5","Cell RNA - BJ [nTPM]":"67.3","Cell RNA - BJ hTERT+ [nTPM]":"80.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"119.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"112.9","Cell RNA - CACO-2 [nTPM]":"197.3","Cell RNA - CAPAN-2 [nTPM]":"69.3","Cell RNA - Daudi [nTPM]":"169.3","Cell RNA - EFO-21 [nTPM]":"101.3","Cell RNA - fHDF\/TERT166 [nTPM]":"83.3","Cell RNA - GAMG [nTPM]":"178.9","Cell RNA - HaCaT [nTPM]":"74.9","Cell RNA - HAP1 [nTPM]":"264.4","Cell RNA - HBEC3-KT [nTPM]":"88.8","Cell RNA - HBF TERT88 [nTPM]":"130.8","Cell RNA - HDLM-2 [nTPM]":"94.3","Cell RNA - HEK 293 [nTPM]":"139.4","Cell RNA - HEL [nTPM]":"221.6","Cell RNA - HeLa [nTPM]":"169.8","Cell RNA - Hep G2 [nTPM]":"106.7","Cell RNA - HHSteC [nTPM]":"40.9","Cell RNA - HL-60 [nTPM]":"171.2","Cell RNA - HMC-1 [nTPM]":"92.4","Cell RNA - HSkMC [nTPM]":"58.1","Cell RNA - hTCEpi [nTPM]":"53.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"133.2","Cell RNA - hTERT-HME1 [nTPM]":"112.0","Cell RNA - hTERT-RPE1 [nTPM]":"61.3","Cell RNA - HUVEC TERT2 [nTPM]":"97.3","Cell RNA - JURKAT [nTPM]":"98.3","Cell RNA - K-562 [nTPM]":"198.2","Cell RNA - Karpas-707 [nTPM]":"112.3","Cell RNA - LHCN-M2 [nTPM]":"68.3","Cell RNA - MCF7 [nTPM]":"82.3","Cell RNA - MOLT-4 [nTPM]":"158.8","Cell RNA - NB-4 [nTPM]":"49.4","Cell RNA - NTERA-2 [nTPM]":"182.8","Cell RNA - OE19 [nTPM]":"77.9","Cell RNA - PC-3 [nTPM]":"102.4","Cell RNA - REH [nTPM]":"185.0","Cell RNA - RH-30 [nTPM]":"139.3","Cell RNA - RPMI-8226 [nTPM]":"107.4","Cell RNA - RPTEC TERT1 [nTPM]":"43.8","Cell RNA - RT4 [nTPM]":"145.4","Cell RNA - SCLC-21H [nTPM]":"159.8","Cell RNA - SH-SY5Y [nTPM]":"150.5","Cell RNA - SiHa [nTPM]":"107.7","Cell RNA - SK-BR-3 [nTPM]":"88.7","Cell RNA - SK-MEL-30 [nTPM]":"65.4","Cell RNA - SuSa [nTPM]":"165.0","Cell RNA - T-47d [nTPM]":"86.4","Cell RNA - THP-1 [nTPM]":"100.5","Cell RNA - TIME [nTPM]":"86.2","Cell RNA - U-138 MG [nTPM]":"98.3","Cell RNA - U-2 OS [nTPM]":"117.2","Cell RNA - U-2197 [nTPM]":"101.3","Cell RNA - U-251 MG [nTPM]":"96.2","Cell RNA - U-266\/70 [nTPM]":"101.0","Cell RNA - U-266\/84 [nTPM]":"134.0","Cell RNA - U-698 [nTPM]":"207.6","Cell RNA - U-87 MG [nTPM]":"66.2","Cell RNA - U-937 [nTPM]":"109.0","Cell RNA - WM-115 [nTPM]":"106.2","Blood RNA - basophil [nTPM]":"16.7","Blood RNA - classical monocyte [nTPM]":"4.7","Blood RNA - eosinophil [nTPM]":"6.0","Blood RNA - gdT-cell [nTPM]":"7.9","Blood RNA - intermediate monocyte [nTPM]":"5.0","Blood RNA - MAIT T-cell [nTPM]":"8.9","Blood RNA - memory B-cell [nTPM]":"5.7","Blood RNA - memory CD4 T-cell [nTPM]":"6.0","Blood RNA - memory CD8 T-cell [nTPM]":"9.5","Blood RNA - myeloid DC [nTPM]":"5.6","Blood RNA - naive B-cell [nTPM]":"6.1","Blood RNA - naive CD4 T-cell [nTPM]":"5.2","Blood RNA - naive CD8 T-cell [nTPM]":"7.1","Blood RNA - neutrophil [nTPM]":"4.7","Blood RNA - NK-cell [nTPM]":"7.3","Blood RNA - non-classical monocyte [nTPM]":"6.1","Blood RNA - plasmacytoid DC [nTPM]":"5.8","Blood RNA - T-reg [nTPM]":"6.8","Blood RNA - total PBMC [nTPM]":"5.5","Brain RNA - amygdala [nTPM]":"11.2","Brain RNA - basal ganglia [nTPM]":"11.3","Brain RNA - cerebellum [nTPM]":"16.9","Brain RNA - cerebral cortex [nTPM]":"12.1","Brain RNA - hippocampal formation [nTPM]":"9.9","Brain RNA - hypothalamus [nTPM]":"11.1","Brain RNA - medulla oblongata [nTPM]":"13.1","Brain RNA - midbrain [nTPM]":"10.3","Brain RNA - pons [nTPM]":"12.0","Brain RNA - spinal cord [nTPM]":"12.2","Brain RNA - thalamus [nTPM]":"9.8","Brain RNA - white matter [nTPM]":"14.6","Single Cell Type RNA - Adipocytes [nTPM]":"47.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"53.9","Single Cell Type RNA - Astrocytes [nTPM]":"21.9","Single Cell Type RNA - B-cells [nTPM]":"57.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"29.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"35.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"38.1","Single Cell Type RNA - Bipolar cells [nTPM]":"79.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"40.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"42.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"35.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"54.3","Single Cell Type RNA - Club cells [nTPM]":"46.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"51.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"104.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"43.2","Single Cell Type RNA - dendritic cells [nTPM]":"64.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"43.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"42.6","Single Cell Type RNA - Early spermatids [nTPM]":"29.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"42.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"48.7","Single Cell Type RNA - Endothelial cells [nTPM]":"44.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"46.7","Single Cell Type RNA - Erythroid cells [nTPM]":"54.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"21.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"46.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"36.1","Single Cell Type RNA - Fibroblasts [nTPM]":"37.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"52.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"48.8","Single Cell Type RNA - granulocytes [nTPM]":"25.3","Single Cell Type RNA - Granulosa cells [nTPM]":"79.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"40.4","Single Cell Type RNA - Hepatocytes [nTPM]":"49.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"35.1","Single Cell Type RNA - Horizontal cells [nTPM]":"87.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"40.6","Single Cell Type RNA - Ionocytes [nTPM]":"34.6","Single Cell Type RNA - Kupffer cells [nTPM]":"31.9","Single Cell Type RNA - Langerhans cells [nTPM]":"33.2","Single Cell Type RNA - Late spermatids [nTPM]":"18.2","Single Cell Type RNA - Leydig cells [nTPM]":"57.5","Single Cell Type RNA - Macrophages [nTPM]":"35.2","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"45.2","Single Cell Type RNA - Muller glia cells [nTPM]":"79.1","Single Cell Type RNA - NK-cells [nTPM]":"73.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"46.1","Single Cell Type RNA - Paneth cells [nTPM]":"30.7","Single Cell Type RNA - Peritubular cells [nTPM]":"55.3","Single Cell Type RNA - Plasma cells [nTPM]":"68.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"34.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"47.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"50.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"135.2","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"54.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"45.5","Single Cell Type RNA - Spermatocytes [nTPM]":"77.6","Single Cell Type RNA - Spermatogonia [nTPM]":"56.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"38.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"33.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"44.6","Single Cell Type RNA - T-cells [nTPM]":"71.6","Single Cell Type RNA - Theca cells [nTPM]":"53.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"49.4","Single Cell Type RNA - Urothelial cells [nTPM]":"30.3"},{"Gene":"SNX3","Gene synonym":["Grd19"],"Ensembl":"ENSG00000112335","Gene description":"Sorting nexin 3","Uniprot":["O60493"],"Chromosome":"6","Position":"108211222-108261246","Protein class":["Disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Microphthalmia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"270000","Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.37e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.74e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.30e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Tissue RNA - adipose tissue [nTPM]":"224.3","Tissue RNA - adrenal gland [nTPM]":"220.8","Tissue RNA - amygdala [nTPM]":"217.3","Tissue RNA - appendix [nTPM]":"131.3","Tissue RNA - basal ganglia [nTPM]":"220.4","Tissue RNA - bone marrow [nTPM]":"296.3","Tissue RNA - breast [nTPM]":"182.6","Tissue RNA - cerebellum [nTPM]":"216.5","Tissue RNA - cerebral cortex [nTPM]":"304.6","Tissue RNA - cervix [nTPM]":"169.5","Tissue RNA - choroid plexus [nTPM]":"208.3","Tissue RNA - colon [nTPM]":"167.6","Tissue RNA - duodenum [nTPM]":"119.4","Tissue RNA - endometrium 1 [nTPM]":"137.9","Tissue RNA - epididymis [nTPM]":"152.8","Tissue RNA - esophagus [nTPM]":"172.4","Tissue RNA - fallopian tube [nTPM]":"144.5","Tissue RNA - gallbladder [nTPM]":"132.0","Tissue RNA - heart muscle [nTPM]":"266.6","Tissue RNA - hippocampal formation [nTPM]":"224.3","Tissue RNA - hypothalamus [nTPM]":"219.6","Tissue RNA - kidney [nTPM]":"168.6","Tissue RNA - liver [nTPM]":"199.0","Tissue RNA - lung [nTPM]":"147.3","Tissue RNA - lymph node [nTPM]":"184.0","Tissue RNA - medulla oblongata [nTPM]":"214.2","Tissue RNA - midbrain [nTPM]":"219.8","Tissue RNA - ovary [nTPM]":"187.5","Tissue RNA - pancreas [nTPM]":"123.6","Tissue RNA - parathyroid gland [nTPM]":"124.4","Tissue RNA - pituitary gland [nTPM]":"95.4","Tissue RNA - placenta [nTPM]":"199.3","Tissue RNA - pons [nTPM]":"215.8","Tissue RNA - prostate [nTPM]":"104.6","Tissue RNA - rectum [nTPM]":"112.9","Tissue RNA - retina [nTPM]":"88.3","Tissue RNA - salivary gland [nTPM]":"134.5","Tissue RNA - seminal vesicle [nTPM]":"119.4","Tissue RNA - skeletal muscle [nTPM]":"323.0","Tissue RNA - skin 1 [nTPM]":"129.0","Tissue RNA - small intestine [nTPM]":"125.2","Tissue RNA - smooth muscle [nTPM]":"157.0","Tissue RNA - spinal cord [nTPM]":"221.1","Tissue RNA - spleen [nTPM]":"145.1","Tissue RNA - stomach 1 [nTPM]":"122.0","Tissue RNA - testis [nTPM]":"109.8","Tissue RNA - thalamus [nTPM]":"218.9","Tissue RNA - thymus [nTPM]":"123.4","Tissue RNA - thyroid gland [nTPM]":"123.2","Tissue RNA - tongue [nTPM]":"285.3","Tissue RNA - tonsil [nTPM]":"163.6","Tissue RNA - urinary bladder [nTPM]":"166.5","Tissue RNA - vagina [nTPM]":"147.8","Tissue RNA - white matter [nTPM]":"234.9","Cell RNA - A-431 [nTPM]":"164.9","Cell RNA - A549 [nTPM]":"98.2","Cell RNA - AF22 [nTPM]":"94.9","Cell RNA - AN3-CA [nTPM]":"314.3","Cell RNA - ASC diff [nTPM]":"505.0","Cell RNA - ASC TERT1 [nTPM]":"377.9","Cell RNA - BEWO [nTPM]":"147.6","Cell RNA - BJ [nTPM]":"241.3","Cell RNA - BJ hTERT+ [nTPM]":"240.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"187.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"231.2","Cell RNA - CACO-2 [nTPM]":"155.0","Cell RNA - CAPAN-2 [nTPM]":"118.8","Cell RNA - Daudi [nTPM]":"138.5","Cell RNA - EFO-21 [nTPM]":"232.8","Cell RNA - fHDF\/TERT166 [nTPM]":"315.3","Cell RNA - GAMG [nTPM]":"328.8","Cell RNA - HaCaT [nTPM]":"128.6","Cell RNA - HAP1 [nTPM]":"212.5","Cell RNA - HBEC3-KT [nTPM]":"207.9","Cell RNA - HBF TERT88 [nTPM]":"254.6","Cell RNA - HDLM-2 [nTPM]":"161.2","Cell RNA - HEK 293 [nTPM]":"136.7","Cell RNA - HEL [nTPM]":"268.1","Cell RNA - HeLa [nTPM]":"110.2","Cell RNA - Hep G2 [nTPM]":"182.6","Cell RNA - HHSteC [nTPM]":"272.9","Cell RNA - HL-60 [nTPM]":"183.9","Cell RNA - HMC-1 [nTPM]":"175.3","Cell RNA - HSkMC [nTPM]":"324.4","Cell RNA - hTCEpi [nTPM]":"279.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"180.1","Cell RNA - hTERT-HME1 [nTPM]":"202.1","Cell RNA - hTERT-RPE1 [nTPM]":"296.9","Cell RNA - HUVEC TERT2 [nTPM]":"312.9","Cell RNA - JURKAT [nTPM]":"131.0","Cell RNA - K-562 [nTPM]":"261.6","Cell RNA - Karpas-707 [nTPM]":"161.1","Cell RNA - LHCN-M2 [nTPM]":"263.1","Cell RNA - MCF7 [nTPM]":"156.6","Cell RNA - MOLT-4 [nTPM]":"70.4","Cell RNA - NB-4 [nTPM]":"403.7","Cell RNA - NTERA-2 [nTPM]":"80.1","Cell RNA - OE19 [nTPM]":"199.1","Cell RNA - PC-3 [nTPM]":"166.2","Cell RNA - REH [nTPM]":"76.2","Cell RNA - RH-30 [nTPM]":"229.7","Cell RNA - RPMI-8226 [nTPM]":"145.4","Cell RNA - RPTEC TERT1 [nTPM]":"300.0","Cell RNA - RT4 [nTPM]":"225.1","Cell RNA - SCLC-21H [nTPM]":"111.0","Cell RNA - SH-SY5Y [nTPM]":"154.9","Cell RNA - SiHa [nTPM]":"155.5","Cell RNA - SK-BR-3 [nTPM]":"197.7","Cell RNA - SK-MEL-30 [nTPM]":"260.4","Cell RNA - SuSa [nTPM]":"212.2","Cell RNA - T-47d [nTPM]":"100.6","Cell RNA - THP-1 [nTPM]":"623.8","Cell RNA - TIME [nTPM]":"235.8","Cell RNA - U-138 MG [nTPM]":"161.0","Cell RNA - U-2 OS [nTPM]":"108.2","Cell RNA - U-2197 [nTPM]":"218.0","Cell RNA - U-251 MG [nTPM]":"319.7","Cell RNA - U-266\/70 [nTPM]":"65.0","Cell RNA - U-266\/84 [nTPM]":"90.7","Cell RNA - U-698 [nTPM]":"148.9","Cell RNA - U-87 MG [nTPM]":"284.2","Cell RNA - U-937 [nTPM]":"332.5","Cell RNA - WM-115 [nTPM]":"197.2","Blood RNA - basophil [nTPM]":"118.5","Blood RNA - classical monocyte [nTPM]":"75.9","Blood RNA - eosinophil [nTPM]":"169.1","Blood RNA - gdT-cell [nTPM]":"37.4","Blood RNA - intermediate monocyte [nTPM]":"70.5","Blood RNA - MAIT T-cell [nTPM]":"48.2","Blood RNA - memory B-cell [nTPM]":"215.3","Blood RNA - memory CD4 T-cell [nTPM]":"43.8","Blood RNA - memory CD8 T-cell [nTPM]":"39.5","Blood RNA - myeloid DC [nTPM]":"109.8","Blood RNA - naive B-cell [nTPM]":"181.6","Blood RNA - naive CD4 T-cell [nTPM]":"44.6","Blood RNA - naive CD8 T-cell [nTPM]":"37.0","Blood RNA - neutrophil [nTPM]":"48.4","Blood RNA - NK-cell [nTPM]":"64.5","Blood RNA - non-classical monocyte [nTPM]":"68.6","Blood RNA - plasmacytoid DC [nTPM]":"132.1","Blood RNA - T-reg [nTPM]":"48.8","Blood RNA - total PBMC [nTPM]":"70.4","Brain RNA - amygdala [nTPM]":"217.3","Brain RNA - basal ganglia [nTPM]":"220.4","Brain RNA - cerebellum [nTPM]":"216.5","Brain RNA - cerebral cortex [nTPM]":"304.6","Brain RNA - hippocampal formation [nTPM]":"224.3","Brain RNA - hypothalamus [nTPM]":"219.6","Brain RNA - medulla oblongata [nTPM]":"214.2","Brain RNA - midbrain [nTPM]":"219.8","Brain RNA - pons [nTPM]":"215.8","Brain RNA - spinal cord [nTPM]":"221.1","Brain RNA - thalamus [nTPM]":"218.9","Brain RNA - white matter [nTPM]":"234.9","Single Cell Type RNA - Adipocytes [nTPM]":"329.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"105.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"70.0","Single Cell Type RNA - Astrocytes [nTPM]":"39.2","Single Cell Type RNA - B-cells [nTPM]":"332.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"378.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"328.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"264.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"231.1","Single Cell Type RNA - Bipolar cells [nTPM]":"44.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"254.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"244.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"395.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"161.5","Single Cell Type RNA - Club cells [nTPM]":"160.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"191.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"685.3","Single Cell Type RNA - dendritic cells [nTPM]":"219.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"199.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"643.7","Single Cell Type RNA - Ductal cells [nTPM]":"307.1","Single Cell Type RNA - Early spermatids [nTPM]":"387.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"144.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"161.1","Single Cell Type RNA - Endothelial cells [nTPM]":"352.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"128.0","Single Cell Type RNA - Erythroid cells [nTPM]":"611.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"55.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"253.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"581.2","Single Cell Type RNA - Fibroblasts [nTPM]":"323.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"101.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"120.0","Single Cell Type RNA - granulocytes [nTPM]":"167.1","Single Cell Type RNA - Granulosa cells [nTPM]":"127.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"275.9","Single Cell Type RNA - Hepatocytes [nTPM]":"240.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"974.2","Single Cell Type RNA - Horizontal cells [nTPM]":"43.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"43.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"154.7","Single Cell Type RNA - Ionocytes [nTPM]":"189.2","Single Cell Type RNA - Kupffer cells [nTPM]":"451.6","Single Cell Type RNA - Langerhans cells [nTPM]":"786.3","Single Cell Type RNA - Late spermatids [nTPM]":"496.6","Single Cell Type RNA - Leydig cells [nTPM]":"288.6","Single Cell Type RNA - Macrophages [nTPM]":"415.7","Single Cell Type RNA - Melanocytes [nTPM]":"368.2","Single Cell Type RNA - Microglial cells [nTPM]":"31.9","Single Cell Type RNA - monocytes [nTPM]":"409.1","Single Cell Type RNA - Muller glia cells [nTPM]":"325.7","Single Cell Type RNA - NK-cells [nTPM]":"209.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"27.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"39.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"260.1","Single Cell Type RNA - Paneth cells [nTPM]":"200.9","Single Cell Type RNA - Peritubular cells [nTPM]":"266.7","Single Cell Type RNA - Plasma cells [nTPM]":"187.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"247.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"321.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"697.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"198.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"53.7","Single Cell Type RNA - Sertoli cells [nTPM]":"256.4","Single Cell Type RNA - Skeletal myocytes [nTPM]":"186.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"304.1","Single Cell Type RNA - Spermatocytes [nTPM]":"316.5","Single Cell Type RNA - Spermatogonia [nTPM]":"173.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"354.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"440.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"618.3","Single Cell Type RNA - T-cells [nTPM]":"181.0","Single Cell Type RNA - Theca cells [nTPM]":"259.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"180.6","Single Cell Type RNA - Urothelial cells [nTPM]":"337.9"},{"Gene":"SOD1","Gene synonym":["ALS","ALS1","IPOA"],"Ensembl":"ENSG00000142168","Gene description":"Superoxide dismutase 1","Uniprot":["P00441"],"Chromosome":"21","Position":"31659666-31668931","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Antioxidant","Oxidoreductase"],"Disease involvement":["Amyotrophic lateral sclerosis","Cancer-related genes","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"1645.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"3357.9","Proximal tubular cells":"3285.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001401","CAB008670"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":44900000,"Blood concentration - Conc. blood MS [pg\/L]":"50000000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Nucleoplasm","Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB008670":"AB_1623312","HPA001401":"AB_1080132"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.59e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Tissue RNA - adipose tissue [nTPM]":"257.6","Tissue RNA - adrenal gland [nTPM]":"597.1","Tissue RNA - amygdala [nTPM]":"558.0","Tissue RNA - appendix [nTPM]":"118.4","Tissue RNA - basal ganglia [nTPM]":"577.4","Tissue RNA - bone marrow [nTPM]":"166.4","Tissue RNA - breast [nTPM]":"233.5","Tissue RNA - cerebellum [nTPM]":"605.2","Tissue RNA - cerebral cortex [nTPM]":"805.1","Tissue RNA - cervix [nTPM]":"206.6","Tissue RNA - choroid plexus [nTPM]":"586.6","Tissue RNA - colon [nTPM]":"251.0","Tissue RNA - duodenum [nTPM]":"360.3","Tissue RNA - endometrium 1 [nTPM]":"179.5","Tissue RNA - epididymis [nTPM]":"228.4","Tissue RNA - esophagus [nTPM]":"221.1","Tissue RNA - fallopian tube [nTPM]":"197.1","Tissue RNA - gallbladder [nTPM]":"206.0","Tissue RNA - heart muscle [nTPM]":"477.3","Tissue RNA - hippocampal formation [nTPM]":"575.1","Tissue RNA - hypothalamus [nTPM]":"619.9","Tissue RNA - kidney [nTPM]":"483.2","Tissue RNA - liver [nTPM]":"1645.6","Tissue RNA - lung [nTPM]":"153.9","Tissue RNA - lymph node [nTPM]":"169.6","Tissue RNA - medulla oblongata [nTPM]":"619.8","Tissue RNA - midbrain [nTPM]":"604.6","Tissue RNA - ovary [nTPM]":"302.1","Tissue RNA - pancreas [nTPM]":"117.1","Tissue RNA - parathyroid gland [nTPM]":"210.6","Tissue RNA - pituitary gland [nTPM]":"236.7","Tissue RNA - placenta [nTPM]":"155.8","Tissue RNA - pons [nTPM]":"653.1","Tissue RNA - prostate [nTPM]":"203.9","Tissue RNA - rectum [nTPM]":"180.5","Tissue RNA - retina [nTPM]":"248.6","Tissue RNA - salivary gland [nTPM]":"160.5","Tissue RNA - seminal vesicle [nTPM]":"204.2","Tissue RNA - skeletal muscle [nTPM]":"428.0","Tissue RNA - skin 1 [nTPM]":"152.1","Tissue RNA - small intestine [nTPM]":"266.7","Tissue RNA - smooth muscle [nTPM]":"136.6","Tissue RNA - spinal cord [nTPM]":"588.1","Tissue RNA - spleen [nTPM]":"147.5","Tissue RNA - stomach 1 [nTPM]":"210.4","Tissue RNA - testis [nTPM]":"132.1","Tissue RNA - thalamus [nTPM]":"585.8","Tissue RNA - thymus [nTPM]":"165.7","Tissue RNA - thyroid gland [nTPM]":"197.4","Tissue RNA - tongue [nTPM]":"355.9","Tissue RNA - tonsil [nTPM]":"151.7","Tissue RNA - urinary bladder [nTPM]":"232.1","Tissue RNA - vagina [nTPM]":"220.6","Tissue RNA - white matter [nTPM]":"634.7","Cell RNA - A-431 [nTPM]":"526.8","Cell RNA - A549 [nTPM]":"451.4","Cell RNA - AF22 [nTPM]":"309.2","Cell RNA - AN3-CA [nTPM]":"312.8","Cell RNA - ASC diff [nTPM]":"407.3","Cell RNA - ASC TERT1 [nTPM]":"282.1","Cell RNA - BEWO [nTPM]":"257.8","Cell RNA - BJ [nTPM]":"430.2","Cell RNA - BJ hTERT+ [nTPM]":"258.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"291.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"217.4","Cell RNA - CACO-2 [nTPM]":"593.6","Cell RNA - CAPAN-2 [nTPM]":"326.0","Cell RNA - Daudi [nTPM]":"628.2","Cell RNA - EFO-21 [nTPM]":"441.2","Cell RNA - fHDF\/TERT166 [nTPM]":"405.8","Cell RNA - GAMG [nTPM]":"517.7","Cell RNA - HaCaT [nTPM]":"186.1","Cell RNA - HAP1 [nTPM]":"453.3","Cell RNA - HBEC3-KT [nTPM]":"320.6","Cell RNA - HBF TERT88 [nTPM]":"239.9","Cell RNA - HDLM-2 [nTPM]":"463.3","Cell RNA - HEK 293 [nTPM]":"540.0","Cell RNA - HEL [nTPM]":"1008.2","Cell RNA - HeLa [nTPM]":"579.5","Cell RNA - Hep G2 [nTPM]":"866.3","Cell RNA - HHSteC [nTPM]":"267.4","Cell RNA - HL-60 [nTPM]":"451.7","Cell RNA - HMC-1 [nTPM]":"363.1","Cell RNA - HSkMC [nTPM]":"294.8","Cell RNA - hTCEpi [nTPM]":"240.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"406.5","Cell RNA - hTERT-HME1 [nTPM]":"225.2","Cell RNA - hTERT-RPE1 [nTPM]":"327.9","Cell RNA - HUVEC TERT2 [nTPM]":"331.2","Cell RNA - JURKAT [nTPM]":"469.0","Cell RNA - K-562 [nTPM]":"704.4","Cell RNA - Karpas-707 [nTPM]":"773.2","Cell RNA - LHCN-M2 [nTPM]":"357.4","Cell RNA - MCF7 [nTPM]":"860.0","Cell RNA - MOLT-4 [nTPM]":"489.0","Cell RNA - NB-4 [nTPM]":"454.5","Cell RNA - NTERA-2 [nTPM]":"466.1","Cell RNA - OE19 [nTPM]":"830.0","Cell RNA - PC-3 [nTPM]":"475.4","Cell RNA - REH [nTPM]":"413.0","Cell RNA - RH-30 [nTPM]":"622.0","Cell RNA - RPMI-8226 [nTPM]":"981.4","Cell RNA - RPTEC TERT1 [nTPM]":"579.4","Cell RNA - RT4 [nTPM]":"320.5","Cell RNA - SCLC-21H [nTPM]":"335.9","Cell RNA - SH-SY5Y [nTPM]":"281.4","Cell RNA - SiHa [nTPM]":"805.1","Cell RNA - SK-BR-3 [nTPM]":"419.4","Cell RNA - SK-MEL-30 [nTPM]":"438.3","Cell RNA - SuSa [nTPM]":"279.2","Cell RNA - T-47d [nTPM]":"484.3","Cell RNA - THP-1 [nTPM]":"393.4","Cell RNA - TIME [nTPM]":"387.4","Cell RNA - U-138 MG [nTPM]":"222.9","Cell RNA - U-2 OS [nTPM]":"489.2","Cell RNA - U-2197 [nTPM]":"304.7","Cell RNA - U-251 MG [nTPM]":"322.0","Cell RNA - U-266\/70 [nTPM]":"583.4","Cell RNA - U-266\/84 [nTPM]":"1374.2","Cell RNA - U-698 [nTPM]":"741.8","Cell RNA - U-87 MG [nTPM]":"455.7","Cell RNA - U-937 [nTPM]":"654.3","Cell RNA - WM-115 [nTPM]":"301.9","Blood RNA - basophil [nTPM]":"204.2","Blood RNA - classical monocyte [nTPM]":"159.7","Blood RNA - eosinophil [nTPM]":"194.0","Blood RNA - gdT-cell [nTPM]":"313.4","Blood RNA - intermediate monocyte [nTPM]":"234.0","Blood RNA - MAIT T-cell [nTPM]":"365.3","Blood RNA - memory B-cell [nTPM]":"427.1","Blood RNA - memory CD4 T-cell [nTPM]":"509.2","Blood RNA - memory CD8 T-cell [nTPM]":"402.4","Blood RNA - myeloid DC [nTPM]":"212.8","Blood RNA - naive B-cell [nTPM]":"310.1","Blood RNA - naive CD4 T-cell [nTPM]":"521.8","Blood RNA - naive CD8 T-cell [nTPM]":"412.1","Blood RNA - neutrophil [nTPM]":"37.8","Blood RNA - NK-cell [nTPM]":"241.4","Blood RNA - non-classical monocyte [nTPM]":"465.4","Blood RNA - plasmacytoid DC [nTPM]":"240.6","Blood RNA - T-reg [nTPM]":"746.0","Blood RNA - total PBMC [nTPM]":"474.5","Brain RNA - amygdala [nTPM]":"558.0","Brain RNA - basal ganglia [nTPM]":"577.4","Brain RNA - cerebellum [nTPM]":"605.2","Brain RNA - cerebral cortex [nTPM]":"805.1","Brain RNA - hippocampal formation [nTPM]":"575.1","Brain RNA - hypothalamus [nTPM]":"619.9","Brain RNA - medulla oblongata [nTPM]":"619.8","Brain RNA - midbrain [nTPM]":"604.6","Brain RNA - pons [nTPM]":"653.1","Brain RNA - spinal cord [nTPM]":"588.1","Brain RNA - thalamus [nTPM]":"585.8","Brain RNA - white matter [nTPM]":"634.7","Single Cell Type RNA - Adipocytes [nTPM]":"319.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"294.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"175.1","Single Cell Type RNA - Astrocytes [nTPM]":"38.2","Single Cell Type RNA - B-cells [nTPM]":"248.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"491.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"672.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"479.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"319.8","Single Cell Type RNA - Bipolar cells [nTPM]":"226.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"264.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"352.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"721.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"527.6","Single Cell Type RNA - Club cells [nTPM]":"294.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"391.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"47.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"703.4","Single Cell Type RNA - dendritic cells [nTPM]":"250.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"703.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1631.7","Single Cell Type RNA - Ductal cells [nTPM]":"426.3","Single Cell Type RNA - Early spermatids [nTPM]":"277.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"410.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"241.2","Single Cell Type RNA - Endothelial cells [nTPM]":"261.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"288.4","Single Cell Type RNA - Erythroid cells [nTPM]":"898.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"39.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"807.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"574.9","Single Cell Type RNA - Fibroblasts [nTPM]":"365.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"198.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"216.3","Single Cell Type RNA - granulocytes [nTPM]":"220.0","Single Cell Type RNA - Granulosa cells [nTPM]":"278.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"318.1","Single Cell Type RNA - Hepatocytes [nTPM]":"3357.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"363.3","Single Cell Type RNA - Horizontal cells [nTPM]":"282.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"45.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"402.7","Single Cell Type RNA - Ionocytes [nTPM]":"366.2","Single Cell Type RNA - Kupffer cells [nTPM]":"220.0","Single Cell Type RNA - Langerhans cells [nTPM]":"318.5","Single Cell Type RNA - Late spermatids [nTPM]":"952.2","Single Cell Type RNA - Leydig cells [nTPM]":"521.9","Single Cell Type RNA - Macrophages [nTPM]":"224.2","Single Cell Type RNA - Melanocytes [nTPM]":"419.8","Single Cell Type RNA - Microglial cells [nTPM]":"29.0","Single Cell Type RNA - monocytes [nTPM]":"313.1","Single Cell Type RNA - Muller glia cells [nTPM]":"598.5","Single Cell Type RNA - NK-cells [nTPM]":"239.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"28.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"68.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"322.8","Single Cell Type RNA - Paneth cells [nTPM]":"600.9","Single Cell Type RNA - Peritubular cells [nTPM]":"528.1","Single Cell Type RNA - Plasma cells [nTPM]":"178.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"567.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1158.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3285.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"638.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"216.5","Single Cell Type RNA - Sertoli cells [nTPM]":"440.4","Single Cell Type RNA - Skeletal myocytes [nTPM]":"313.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"404.5","Single Cell Type RNA - Spermatocytes [nTPM]":"211.7","Single Cell Type RNA - Spermatogonia [nTPM]":"506.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"379.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"349.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"725.9","Single Cell Type RNA - T-cells [nTPM]":"423.1","Single Cell Type RNA - Theca cells [nTPM]":"470.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"593.6","Single Cell Type RNA - Urothelial cells [nTPM]":"497.7"},{"Gene":"SOD2","Gene synonym":["GClnc1"],"Ensembl":"ENSG00000112096","Gene description":"Superoxide dismutase 2","Uniprot":["P04179"],"Chromosome":"6","Position":"159669069-159762529","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"bone marrow":"1083.7","skeletal muscle":"3230.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"2508.2","Prostatic glandular cells":"3524.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"neutrophil":"4470.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"granulocytes":"4470.5"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+":"1611.9","GAMG":"614.3","HSkMC":"688.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001814","CAB002013"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"55000000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB002013":null,"HPA001814":"AB_1080134"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.72e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Tissue RNA - adipose tissue [nTPM]":"324.8","Tissue RNA - adrenal gland [nTPM]":"245.9","Tissue RNA - amygdala [nTPM]":"66.8","Tissue RNA - appendix [nTPM]":"522.8","Tissue RNA - basal ganglia [nTPM]":"43.2","Tissue RNA - bone marrow [nTPM]":"1083.7","Tissue RNA - breast [nTPM]":"169.0","Tissue RNA - cerebellum [nTPM]":"37.8","Tissue RNA - cerebral cortex [nTPM]":"125.8","Tissue RNA - cervix [nTPM]":"92.6","Tissue RNA - choroid plexus [nTPM]":"99.7","Tissue RNA - colon [nTPM]":"126.4","Tissue RNA - duodenum [nTPM]":"60.5","Tissue RNA - endometrium 1 [nTPM]":"105.4","Tissue RNA - epididymis [nTPM]":"7.2","Tissue RNA - esophagus [nTPM]":"136.5","Tissue RNA - fallopian tube [nTPM]":"118.5","Tissue RNA - gallbladder [nTPM]":"121.8","Tissue RNA - heart muscle [nTPM]":"178.5","Tissue RNA - hippocampal formation [nTPM]":"37.0","Tissue RNA - hypothalamus [nTPM]":"101.0","Tissue RNA - kidney [nTPM]":"252.4","Tissue RNA - liver [nTPM]":"459.8","Tissue RNA - lung [nTPM]":"266.5","Tissue RNA - lymph node [nTPM]":"64.8","Tissue RNA - medulla oblongata [nTPM]":"250.0","Tissue RNA - midbrain [nTPM]":"96.1","Tissue RNA - ovary [nTPM]":"55.8","Tissue RNA - pancreas [nTPM]":"212.3","Tissue RNA - parathyroid gland [nTPM]":"69.1","Tissue RNA - pituitary gland [nTPM]":"42.7","Tissue RNA - placenta [nTPM]":"62.9","Tissue RNA - pons [nTPM]":"192.9","Tissue RNA - prostate [nTPM]":"130.8","Tissue RNA - rectum [nTPM]":"37.9","Tissue RNA - retina [nTPM]":"25.1","Tissue RNA - salivary gland [nTPM]":"328.8","Tissue RNA - seminal vesicle [nTPM]":"43.9","Tissue RNA - skeletal muscle [nTPM]":"3230.1","Tissue RNA - skin 1 [nTPM]":"90.0","Tissue RNA - small intestine [nTPM]":"83.7","Tissue RNA - smooth muscle [nTPM]":"108.4","Tissue RNA - spinal cord [nTPM]":"62.5","Tissue RNA - spleen [nTPM]":"81.4","Tissue RNA - stomach 1 [nTPM]":"120.4","Tissue RNA - testis [nTPM]":"39.6","Tissue RNA - thalamus [nTPM]":"153.1","Tissue RNA - thymus [nTPM]":"38.2","Tissue RNA - thyroid gland [nTPM]":"67.2","Tissue RNA - tongue [nTPM]":"312.6","Tissue RNA - tonsil [nTPM]":"65.0","Tissue RNA - urinary bladder [nTPM]":"514.9","Tissue RNA - vagina [nTPM]":"97.9","Tissue RNA - white matter [nTPM]":"85.4","Cell RNA - A-431 [nTPM]":"35.8","Cell RNA - A549 [nTPM]":"46.3","Cell RNA - AF22 [nTPM]":"37.3","Cell RNA - AN3-CA [nTPM]":"85.1","Cell RNA - ASC diff [nTPM]":"229.0","Cell RNA - ASC TERT1 [nTPM]":"378.7","Cell RNA - BEWO [nTPM]":"20.5","Cell RNA - BJ [nTPM]":"52.7","Cell RNA - BJ hTERT+ [nTPM]":"1611.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"57.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"131.1","Cell RNA - CACO-2 [nTPM]":"91.3","Cell RNA - CAPAN-2 [nTPM]":"19.4","Cell RNA - Daudi [nTPM]":"70.7","Cell RNA - EFO-21 [nTPM]":"144.5","Cell RNA - fHDF\/TERT166 [nTPM]":"54.1","Cell RNA - GAMG [nTPM]":"614.3","Cell RNA - HaCaT [nTPM]":"58.9","Cell RNA - HAP1 [nTPM]":"39.1","Cell RNA - HBEC3-KT [nTPM]":"42.5","Cell RNA - HBF TERT88 [nTPM]":"42.4","Cell RNA - HDLM-2 [nTPM]":"71.2","Cell RNA - HEK 293 [nTPM]":"87.2","Cell RNA - HEL [nTPM]":"74.5","Cell RNA - HeLa [nTPM]":"71.8","Cell RNA - Hep G2 [nTPM]":"152.3","Cell RNA - HHSteC [nTPM]":"169.5","Cell RNA - HL-60 [nTPM]":"74.0","Cell RNA - HMC-1 [nTPM]":"31.9","Cell RNA - HSkMC [nTPM]":"688.9","Cell RNA - hTCEpi [nTPM]":"68.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"180.9","Cell RNA - hTERT-HME1 [nTPM]":"133.6","Cell RNA - hTERT-RPE1 [nTPM]":"40.7","Cell RNA - HUVEC TERT2 [nTPM]":"30.0","Cell RNA - JURKAT [nTPM]":"44.9","Cell RNA - K-562 [nTPM]":"106.7","Cell RNA - Karpas-707 [nTPM]":"82.2","Cell RNA - LHCN-M2 [nTPM]":"55.4","Cell RNA - MCF7 [nTPM]":"37.6","Cell RNA - MOLT-4 [nTPM]":"60.3","Cell RNA - NB-4 [nTPM]":"46.6","Cell RNA - NTERA-2 [nTPM]":"63.3","Cell RNA - OE19 [nTPM]":"41.5","Cell RNA - PC-3 [nTPM]":"55.4","Cell RNA - REH [nTPM]":"79.6","Cell RNA - RH-30 [nTPM]":"50.3","Cell RNA - RPMI-8226 [nTPM]":"63.9","Cell RNA - RPTEC TERT1 [nTPM]":"106.2","Cell RNA - RT4 [nTPM]":"56.6","Cell RNA - SCLC-21H [nTPM]":"71.5","Cell RNA - SH-SY5Y [nTPM]":"29.5","Cell RNA - SiHa [nTPM]":"105.1","Cell RNA - SK-BR-3 [nTPM]":"52.4","Cell RNA - SK-MEL-30 [nTPM]":"21.4","Cell RNA - SuSa [nTPM]":"14.1","Cell RNA - T-47d [nTPM]":"33.1","Cell RNA - THP-1 [nTPM]":"33.7","Cell RNA - TIME [nTPM]":"30.4","Cell RNA - U-138 MG [nTPM]":"168.6","Cell RNA - U-2 OS [nTPM]":"62.1","Cell RNA - U-2197 [nTPM]":"92.5","Cell RNA - U-251 MG [nTPM]":"87.9","Cell RNA - U-266\/70 [nTPM]":"37.8","Cell RNA - U-266\/84 [nTPM]":"100.2","Cell RNA - U-698 [nTPM]":"86.5","Cell RNA - U-87 MG [nTPM]":"186.7","Cell RNA - U-937 [nTPM]":"57.4","Cell RNA - WM-115 [nTPM]":"23.6","Blood RNA - basophil [nTPM]":"146.3","Blood RNA - classical monocyte [nTPM]":"364.4","Blood RNA - eosinophil [nTPM]":"181.1","Blood RNA - gdT-cell [nTPM]":"38.8","Blood RNA - intermediate monocyte [nTPM]":"273.9","Blood RNA - MAIT T-cell [nTPM]":"43.4","Blood RNA - memory B-cell [nTPM]":"43.4","Blood RNA - memory CD4 T-cell [nTPM]":"54.9","Blood RNA - memory CD8 T-cell [nTPM]":"38.5","Blood RNA - myeloid DC [nTPM]":"105.2","Blood RNA - naive B-cell [nTPM]":"38.3","Blood RNA - naive CD4 T-cell [nTPM]":"45.0","Blood RNA - naive CD8 T-cell [nTPM]":"36.9","Blood RNA - neutrophil [nTPM]":"4470.5","Blood RNA - NK-cell [nTPM]":"19.1","Blood RNA - non-classical monocyte [nTPM]":"445.3","Blood RNA - plasmacytoid DC [nTPM]":"14.8","Blood RNA - T-reg [nTPM]":"87.9","Blood RNA - total PBMC [nTPM]":"340.0","Brain RNA - amygdala [nTPM]":"66.8","Brain RNA - basal ganglia [nTPM]":"43.2","Brain RNA - cerebellum [nTPM]":"37.8","Brain RNA - cerebral cortex [nTPM]":"125.8","Brain RNA - hippocampal formation [nTPM]":"37.0","Brain RNA - hypothalamus [nTPM]":"101.0","Brain RNA - medulla oblongata [nTPM]":"250.0","Brain RNA - midbrain [nTPM]":"96.1","Brain RNA - pons [nTPM]":"192.9","Brain RNA - spinal cord [nTPM]":"62.5","Brain RNA - thalamus [nTPM]":"153.1","Brain RNA - white matter [nTPM]":"85.4","Single Cell Type RNA - Adipocytes [nTPM]":"303.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"201.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"746.1","Single Cell Type RNA - Astrocytes [nTPM]":"13.4","Single Cell Type RNA - B-cells [nTPM]":"99.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"684.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1144.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2508.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"114.4","Single Cell Type RNA - Bipolar cells [nTPM]":"45.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"150.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"96.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"287.4","Single Cell Type RNA - Club cells [nTPM]":"613.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"237.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.3","Single Cell Type RNA - dendritic cells [nTPM]":"43.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"153.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"86.1","Single Cell Type RNA - Ductal cells [nTPM]":"1400.2","Single Cell Type RNA - Early spermatids [nTPM]":"318.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"281.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"649.8","Single Cell Type RNA - Endothelial cells [nTPM]":"593.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"79.6","Single Cell Type RNA - Erythroid cells [nTPM]":"101.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"31.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1389.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"51.2","Single Cell Type RNA - Fibroblasts [nTPM]":"1098.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"103.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1080.1","Single Cell Type RNA - granulocytes [nTPM]":"112.3","Single Cell Type RNA - Granulosa cells [nTPM]":"23.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"58.9","Single Cell Type RNA - Hepatocytes [nTPM]":"395.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"292.0","Single Cell Type RNA - Horizontal cells [nTPM]":"32.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"30.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"92.7","Single Cell Type RNA - Ionocytes [nTPM]":"339.7","Single Cell Type RNA - Kupffer cells [nTPM]":"333.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1425.8","Single Cell Type RNA - Late spermatids [nTPM]":"111.5","Single Cell Type RNA - Leydig cells [nTPM]":"58.1","Single Cell Type RNA - Macrophages [nTPM]":"1031.2","Single Cell Type RNA - Melanocytes [nTPM]":"521.2","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"339.9","Single Cell Type RNA - Muller glia cells [nTPM]":"50.4","Single Cell Type RNA - NK-cells [nTPM]":"35.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"581.6","Single Cell Type RNA - Paneth cells [nTPM]":"111.3","Single Cell Type RNA - Peritubular cells [nTPM]":"65.1","Single Cell Type RNA - Plasma cells [nTPM]":"101.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3524.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"128.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"530.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"269.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"61.8","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1164.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"407.3","Single Cell Type RNA - Spermatocytes [nTPM]":"91.7","Single Cell Type RNA - Spermatogonia [nTPM]":"51.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"258.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"681.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"27.2","Single Cell Type RNA - T-cells [nTPM]":"119.4","Single Cell Type RNA - Theca cells [nTPM]":"38.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"148.1","Single Cell Type RNA - Urothelial cells [nTPM]":"1195.7"},{"Gene":"SON","Gene synonym":["BASS1","C21orf50","DBP-5","FLJ21099","FLJ33914","KIAA1019","NREBP"],"Ensembl":"ENSG00000159140","Gene description":"SON DNA and RNA binding protein","Uniprot":["P18583"],"Chromosome":"21","Position":"33543038-33577481","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Cell cycle","mRNA processing","mRNA splicing"],"Molecular function":["DNA-binding","RNA-binding"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023535","HPA031755","HPA031756"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 43: Cardiomyocytes - Nuclear processes","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA023535":"AB_1857362","HPA031755":"AB_2674029","HPA031756":"AB_2674030"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.75e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Tissue RNA - adipose tissue [nTPM]":"69.1","Tissue RNA - adrenal gland [nTPM]":"62.5","Tissue RNA - amygdala [nTPM]":"45.6","Tissue RNA - appendix [nTPM]":"57.8","Tissue RNA - basal ganglia [nTPM]":"52.1","Tissue RNA - bone marrow [nTPM]":"161.9","Tissue RNA - breast [nTPM]":"65.0","Tissue RNA - cerebellum [nTPM]":"56.4","Tissue RNA - cerebral cortex [nTPM]":"58.6","Tissue RNA - cervix [nTPM]":"59.4","Tissue RNA - choroid plexus [nTPM]":"71.9","Tissue RNA - colon [nTPM]":"64.1","Tissue RNA - duodenum [nTPM]":"44.9","Tissue RNA - endometrium 1 [nTPM]":"66.9","Tissue RNA - epididymis [nTPM]":"61.5","Tissue RNA - esophagus [nTPM]":"60.7","Tissue RNA - fallopian tube [nTPM]":"68.5","Tissue RNA - gallbladder [nTPM]":"43.2","Tissue RNA - heart muscle [nTPM]":"60.3","Tissue RNA - hippocampal formation [nTPM]":"43.7","Tissue RNA - hypothalamus [nTPM]":"45.7","Tissue RNA - kidney [nTPM]":"49.4","Tissue RNA - liver [nTPM]":"60.3","Tissue RNA - lung [nTPM]":"65.2","Tissue RNA - lymph node [nTPM]":"81.0","Tissue RNA - medulla oblongata [nTPM]":"49.8","Tissue RNA - midbrain [nTPM]":"46.8","Tissue RNA - ovary [nTPM]":"76.7","Tissue RNA - pancreas [nTPM]":"63.4","Tissue RNA - parathyroid gland [nTPM]":"92.8","Tissue RNA - pituitary gland [nTPM]":"63.9","Tissue RNA - placenta [nTPM]":"60.9","Tissue RNA - pons [nTPM]":"51.3","Tissue RNA - prostate [nTPM]":"61.2","Tissue RNA - rectum [nTPM]":"56.4","Tissue RNA - retina [nTPM]":"91.8","Tissue RNA - salivary gland [nTPM]":"64.3","Tissue RNA - seminal vesicle [nTPM]":"52.6","Tissue RNA - skeletal muscle [nTPM]":"89.4","Tissue RNA - skin 1 [nTPM]":"64.1","Tissue RNA - small intestine [nTPM]":"67.8","Tissue RNA - smooth muscle [nTPM]":"51.1","Tissue RNA - spinal cord [nTPM]":"47.6","Tissue RNA - spleen [nTPM]":"71.5","Tissue RNA - stomach 1 [nTPM]":"66.8","Tissue RNA - testis [nTPM]":"48.0","Tissue RNA - thalamus [nTPM]":"47.8","Tissue RNA - thymus [nTPM]":"92.8","Tissue RNA - thyroid gland [nTPM]":"64.4","Tissue RNA - tongue [nTPM]":"53.8","Tissue RNA - tonsil [nTPM]":"76.2","Tissue RNA - urinary bladder [nTPM]":"62.9","Tissue RNA - vagina [nTPM]":"55.9","Tissue RNA - white matter [nTPM]":"65.8","Cell RNA - A-431 [nTPM]":"105.7","Cell RNA - A549 [nTPM]":"59.7","Cell RNA - AF22 [nTPM]":"126.1","Cell RNA - AN3-CA [nTPM]":"72.7","Cell RNA - ASC diff [nTPM]":"108.1","Cell RNA - ASC TERT1 [nTPM]":"98.3","Cell RNA - BEWO [nTPM]":"89.2","Cell RNA - BJ [nTPM]":"77.2","Cell RNA - BJ hTERT+ [nTPM]":"88.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"73.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"69.6","Cell RNA - CACO-2 [nTPM]":"89.5","Cell RNA - CAPAN-2 [nTPM]":"75.2","Cell RNA - Daudi [nTPM]":"163.8","Cell RNA - EFO-21 [nTPM]":"45.9","Cell RNA - fHDF\/TERT166 [nTPM]":"114.8","Cell RNA - GAMG [nTPM]":"86.6","Cell RNA - HaCaT [nTPM]":"76.4","Cell RNA - HAP1 [nTPM]":"152.4","Cell RNA - HBEC3-KT [nTPM]":"113.0","Cell RNA - HBF TERT88 [nTPM]":"109.7","Cell RNA - HDLM-2 [nTPM]":"85.4","Cell RNA - HEK 293 [nTPM]":"77.9","Cell RNA - HEL [nTPM]":"220.0","Cell RNA - HeLa [nTPM]":"78.2","Cell RNA - Hep G2 [nTPM]":"111.3","Cell RNA - HHSteC [nTPM]":"79.3","Cell RNA - HL-60 [nTPM]":"215.0","Cell RNA - HMC-1 [nTPM]":"110.8","Cell RNA - HSkMC [nTPM]":"100.6","Cell RNA - hTCEpi [nTPM]":"128.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"88.0","Cell RNA - hTERT-HME1 [nTPM]":"124.5","Cell RNA - hTERT-RPE1 [nTPM]":"91.3","Cell RNA - HUVEC TERT2 [nTPM]":"110.1","Cell RNA - JURKAT [nTPM]":"91.2","Cell RNA - K-562 [nTPM]":"172.9","Cell RNA - Karpas-707 [nTPM]":"150.9","Cell RNA - LHCN-M2 [nTPM]":"101.1","Cell RNA - MCF7 [nTPM]":"101.6","Cell RNA - MOLT-4 [nTPM]":"121.0","Cell RNA - NB-4 [nTPM]":"112.9","Cell RNA - NTERA-2 [nTPM]":"136.0","Cell RNA - OE19 [nTPM]":"108.5","Cell RNA - PC-3 [nTPM]":"60.7","Cell RNA - REH [nTPM]":"121.5","Cell RNA - RH-30 [nTPM]":"133.8","Cell RNA - RPMI-8226 [nTPM]":"118.1","Cell RNA - RPTEC TERT1 [nTPM]":"109.7","Cell RNA - RT4 [nTPM]":"102.1","Cell RNA - SCLC-21H [nTPM]":"84.1","Cell RNA - SH-SY5Y [nTPM]":"77.6","Cell RNA - SiHa [nTPM]":"124.2","Cell RNA - SK-BR-3 [nTPM]":"100.3","Cell RNA - SK-MEL-30 [nTPM]":"91.3","Cell RNA - SuSa [nTPM]":"103.6","Cell RNA - T-47d [nTPM]":"93.6","Cell RNA - THP-1 [nTPM]":"128.3","Cell RNA - TIME [nTPM]":"116.0","Cell RNA - U-138 MG [nTPM]":"83.4","Cell RNA - U-2 OS [nTPM]":"73.1","Cell RNA - U-2197 [nTPM]":"66.6","Cell RNA - U-251 MG [nTPM]":"87.0","Cell RNA - U-266\/70 [nTPM]":"144.8","Cell RNA - U-266\/84 [nTPM]":"143.2","Cell RNA - U-698 [nTPM]":"193.9","Cell RNA - U-87 MG [nTPM]":"84.7","Cell RNA - U-937 [nTPM]":"172.3","Cell RNA - WM-115 [nTPM]":"78.9","Blood RNA - basophil [nTPM]":"33.7","Blood RNA - classical monocyte [nTPM]":"20.3","Blood RNA - eosinophil [nTPM]":"28.7","Blood RNA - gdT-cell [nTPM]":"20.7","Blood RNA - intermediate monocyte [nTPM]":"18.4","Blood RNA - MAIT T-cell [nTPM]":"20.8","Blood RNA - memory B-cell [nTPM]":"30.4","Blood RNA - memory CD4 T-cell [nTPM]":"22.9","Blood RNA - memory CD8 T-cell [nTPM]":"22.1","Blood RNA - myeloid DC [nTPM]":"15.8","Blood RNA - naive B-cell [nTPM]":"28.2","Blood RNA - naive CD4 T-cell [nTPM]":"22.7","Blood RNA - naive CD8 T-cell [nTPM]":"22.3","Blood RNA - neutrophil [nTPM]":"37.4","Blood RNA - NK-cell [nTPM]":"22.3","Blood RNA - non-classical monocyte [nTPM]":"24.5","Blood RNA - plasmacytoid DC [nTPM]":"38.5","Blood RNA - T-reg [nTPM]":"22.1","Blood RNA - total PBMC [nTPM]":"15.8","Brain RNA - amygdala [nTPM]":"45.6","Brain RNA - basal ganglia [nTPM]":"52.1","Brain RNA - cerebellum [nTPM]":"56.4","Brain RNA - cerebral cortex [nTPM]":"58.6","Brain RNA - hippocampal formation [nTPM]":"43.7","Brain RNA - hypothalamus [nTPM]":"45.7","Brain RNA - medulla oblongata [nTPM]":"49.8","Brain RNA - midbrain [nTPM]":"46.8","Brain RNA - pons [nTPM]":"51.3","Brain RNA - spinal cord [nTPM]":"47.6","Brain RNA - thalamus [nTPM]":"47.8","Brain RNA - white matter [nTPM]":"65.8","Single Cell Type RNA - Adipocytes [nTPM]":"374.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"410.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"298.2","Single Cell Type RNA - Astrocytes [nTPM]":"201.4","Single Cell Type RNA - B-cells [nTPM]":"355.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"433.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"312.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"310.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"250.4","Single Cell Type RNA - Bipolar cells [nTPM]":"389.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"213.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"219.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"351.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"320.3","Single Cell Type RNA - Club cells [nTPM]":"298.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"301.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"221.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"224.1","Single Cell Type RNA - dendritic cells [nTPM]":"423.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"276.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"193.7","Single Cell Type RNA - Ductal cells [nTPM]":"209.7","Single Cell Type RNA - Early spermatids [nTPM]":"97.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"296.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"412.2","Single Cell Type RNA - Endothelial cells [nTPM]":"342.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"186.8","Single Cell Type RNA - Erythroid cells [nTPM]":"375.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"93.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"207.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"164.7","Single Cell Type RNA - Fibroblasts [nTPM]":"333.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"208.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"335.8","Single Cell Type RNA - granulocytes [nTPM]":"418.2","Single Cell Type RNA - Granulosa cells [nTPM]":"216.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"304.8","Single Cell Type RNA - Hepatocytes [nTPM]":"344.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"170.1","Single Cell Type RNA - Horizontal cells [nTPM]":"455.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"105.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"256.0","Single Cell Type RNA - Ionocytes [nTPM]":"219.7","Single Cell Type RNA - Kupffer cells [nTPM]":"237.2","Single Cell Type RNA - Langerhans cells [nTPM]":"307.4","Single Cell Type RNA - Late spermatids [nTPM]":"66.0","Single Cell Type RNA - Leydig cells [nTPM]":"393.9","Single Cell Type RNA - Macrophages [nTPM]":"261.0","Single Cell Type RNA - Melanocytes [nTPM]":"218.7","Single Cell Type RNA - Microglial cells [nTPM]":"146.1","Single Cell Type RNA - monocytes [nTPM]":"256.8","Single Cell Type RNA - Muller glia cells [nTPM]":"335.7","Single Cell Type RNA - NK-cells [nTPM]":"347.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"131.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"162.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"190.0","Single Cell Type RNA - Paneth cells [nTPM]":"217.2","Single Cell Type RNA - Peritubular cells [nTPM]":"393.4","Single Cell Type RNA - Plasma cells [nTPM]":"294.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"250.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"198.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"225.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"288.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"372.0","Single Cell Type RNA - Sertoli cells [nTPM]":"381.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"505.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"399.2","Single Cell Type RNA - Spermatocytes [nTPM]":"470.1","Single Cell Type RNA - Spermatogonia [nTPM]":"334.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"197.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"394.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"327.1","Single Cell Type RNA - T-cells [nTPM]":"378.2","Single Cell Type RNA - Theca cells [nTPM]":"183.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"246.3","Single Cell Type RNA - Urothelial cells [nTPM]":"226.5"},{"Gene":"SORD","Gene synonym":[],"Ensembl":"ENSG00000140263","Gene description":"Sorbitol dehydrogenase","Uniprot":["Q00796"],"Chromosome":"15","Position":"45023147-45077185","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"163.8","liver":"247.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Exocrine glandular cells":"138.7","Hepatocytes":"649.4","Prostatic glandular cells":"218.8","Proximal tubular cells":"270.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"liver cancer":"30.3","prostate cancer":"72.5","thyroid cancer":"30.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"basophil":"86.3","eosinophil":"55.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"granulocytes":"86.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SK-BR-3":"57.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040260","HPA040621"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2800000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA040260":"AB_10794872","HPA040621":"AB_10795384"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.14e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.04e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Tissue RNA - adipose tissue [nTPM]":"2.0","Tissue RNA - adrenal gland [nTPM]":"15.7","Tissue RNA - amygdala [nTPM]":"4.9","Tissue RNA - appendix [nTPM]":"3.1","Tissue RNA - basal ganglia [nTPM]":"3.8","Tissue RNA - bone marrow [nTPM]":"2.8","Tissue RNA - breast [nTPM]":"53.8","Tissue RNA - cerebellum [nTPM]":"7.4","Tissue RNA - cerebral cortex [nTPM]":"8.4","Tissue RNA - cervix [nTPM]":"163.8","Tissue RNA - choroid plexus [nTPM]":"1.9","Tissue RNA - colon [nTPM]":"5.3","Tissue RNA - duodenum [nTPM]":"7.5","Tissue RNA - endometrium 1 [nTPM]":"4.3","Tissue RNA - epididymis [nTPM]":"6.9","Tissue RNA - esophagus [nTPM]":"10.2","Tissue RNA - fallopian tube [nTPM]":"6.7","Tissue RNA - gallbladder [nTPM]":"8.2","Tissue RNA - heart muscle [nTPM]":"5.6","Tissue RNA - hippocampal formation [nTPM]":"5.0","Tissue RNA - hypothalamus [nTPM]":"4.5","Tissue RNA - kidney [nTPM]":"50.3","Tissue RNA - liver [nTPM]":"247.0","Tissue RNA - lung [nTPM]":"3.2","Tissue RNA - lymph node [nTPM]":"2.6","Tissue RNA - medulla oblongata [nTPM]":"4.3","Tissue RNA - midbrain [nTPM]":"3.7","Tissue RNA - ovary [nTPM]":"2.4","Tissue RNA - pancreas [nTPM]":"5.7","Tissue RNA - parathyroid gland [nTPM]":"4.4","Tissue RNA - pituitary gland [nTPM]":"3.1","Tissue RNA - placenta [nTPM]":"2.5","Tissue RNA - pons [nTPM]":"4.0","Tissue RNA - prostate [nTPM]":"87.9","Tissue RNA - rectum [nTPM]":"7.8","Tissue RNA - retina [nTPM]":"4.8","Tissue RNA - salivary gland [nTPM]":"5.3","Tissue RNA - seminal vesicle [nTPM]":"27.0","Tissue RNA - skeletal muscle [nTPM]":"2.2","Tissue RNA - skin 1 [nTPM]":"16.6","Tissue RNA - small intestine [nTPM]":"7.2","Tissue RNA - smooth muscle [nTPM]":"3.5","Tissue RNA - spinal cord [nTPM]":"4.2","Tissue RNA - spleen [nTPM]":"2.3","Tissue RNA - stomach 1 [nTPM]":"9.2","Tissue RNA - testis [nTPM]":"12.2","Tissue RNA - thalamus [nTPM]":"3.9","Tissue RNA - thymus [nTPM]":"3.7","Tissue RNA - thyroid gland [nTPM]":"89.4","Tissue RNA - tongue [nTPM]":"2.8","Tissue RNA - tonsil [nTPM]":"3.4","Tissue RNA - urinary bladder [nTPM]":"9.1","Tissue RNA - vagina [nTPM]":"6.9","Tissue RNA - white matter [nTPM]":"6.3","Cell RNA - A-431 [nTPM]":"12.3","Cell RNA - A549 [nTPM]":"12.2","Cell RNA - AF22 [nTPM]":"4.7","Cell RNA - AN3-CA [nTPM]":"20.8","Cell RNA - ASC diff [nTPM]":"4.4","Cell RNA - ASC TERT1 [nTPM]":"5.3","Cell RNA - BEWO [nTPM]":"5.9","Cell RNA - BJ [nTPM]":"1.8","Cell RNA - BJ hTERT+ [nTPM]":"3.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.0","Cell RNA - CACO-2 [nTPM]":"12.2","Cell RNA - CAPAN-2 [nTPM]":"5.8","Cell RNA - Daudi [nTPM]":"2.7","Cell RNA - EFO-21 [nTPM]":"8.0","Cell RNA - fHDF\/TERT166 [nTPM]":"5.4","Cell RNA - GAMG [nTPM]":"4.1","Cell RNA - HaCaT [nTPM]":"17.6","Cell RNA - HAP1 [nTPM]":"19.9","Cell RNA - HBEC3-KT [nTPM]":"19.1","Cell RNA - HBF TERT88 [nTPM]":"9.2","Cell RNA - HDLM-2 [nTPM]":"29.9","Cell RNA - HEK 293 [nTPM]":"12.3","Cell RNA - HEL [nTPM]":"13.5","Cell RNA - HeLa [nTPM]":"12.1","Cell RNA - Hep G2 [nTPM]":"50.3","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"18.0","Cell RNA - HMC-1 [nTPM]":"25.5","Cell RNA - HSkMC [nTPM]":"6.7","Cell RNA - hTCEpi [nTPM]":"18.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.6","Cell RNA - hTERT-HME1 [nTPM]":"9.5","Cell RNA - hTERT-RPE1 [nTPM]":"5.4","Cell RNA - HUVEC TERT2 [nTPM]":"12.5","Cell RNA - JURKAT [nTPM]":"15.1","Cell RNA - K-562 [nTPM]":"11.7","Cell RNA - Karpas-707 [nTPM]":"10.6","Cell RNA - LHCN-M2 [nTPM]":"14.9","Cell RNA - MCF7 [nTPM]":"8.1","Cell RNA - MOLT-4 [nTPM]":"18.4","Cell RNA - NB-4 [nTPM]":"38.3","Cell RNA - NTERA-2 [nTPM]":"39.0","Cell RNA - OE19 [nTPM]":"29.4","Cell RNA - PC-3 [nTPM]":"13.8","Cell RNA - REH [nTPM]":"0.9","Cell RNA - RH-30 [nTPM]":"16.6","Cell RNA - RPMI-8226 [nTPM]":"6.4","Cell RNA - RPTEC TERT1 [nTPM]":"16.8","Cell RNA - RT4 [nTPM]":"12.1","Cell RNA - SCLC-21H [nTPM]":"25.1","Cell RNA - SH-SY5Y [nTPM]":"12.2","Cell RNA - SiHa [nTPM]":"2.1","Cell RNA - SK-BR-3 [nTPM]":"57.3","Cell RNA - SK-MEL-30 [nTPM]":"5.9","Cell RNA - SuSa [nTPM]":"5.2","Cell RNA - T-47d [nTPM]":"16.4","Cell RNA - THP-1 [nTPM]":"22.5","Cell RNA - TIME [nTPM]":"4.7","Cell RNA - U-138 MG [nTPM]":"3.5","Cell RNA - U-2 OS [nTPM]":"38.0","Cell RNA - U-2197 [nTPM]":"1.6","Cell RNA - U-251 MG [nTPM]":"5.8","Cell RNA - U-266\/70 [nTPM]":"8.7","Cell RNA - U-266\/84 [nTPM]":"4.5","Cell RNA - U-698 [nTPM]":"4.4","Cell RNA - U-87 MG [nTPM]":"14.2","Cell RNA - U-937 [nTPM]":"18.6","Cell RNA - WM-115 [nTPM]":"10.6","Blood RNA - basophil [nTPM]":"86.3","Blood RNA - classical monocyte [nTPM]":"1.7","Blood RNA - eosinophil [nTPM]":"55.9","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"1.7","Blood RNA - memory B-cell [nTPM]":"5.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"1.6","Blood RNA - myeloid DC [nTPM]":"1.7","Blood RNA - naive B-cell [nTPM]":"6.9","Blood RNA - naive CD4 T-cell [nTPM]":"1.6","Blood RNA - naive CD8 T-cell [nTPM]":"1.4","Blood RNA - neutrophil [nTPM]":"3.8","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"2.1","Blood RNA - plasmacytoid DC [nTPM]":"2.4","Blood RNA - T-reg [nTPM]":"2.5","Blood RNA - total PBMC [nTPM]":"2.0","Brain RNA - amygdala [nTPM]":"4.9","Brain RNA - basal ganglia [nTPM]":"3.8","Brain RNA - cerebellum [nTPM]":"7.4","Brain RNA - cerebral cortex [nTPM]":"8.4","Brain RNA - hippocampal formation [nTPM]":"5.0","Brain RNA - hypothalamus [nTPM]":"4.5","Brain RNA - medulla oblongata [nTPM]":"4.3","Brain RNA - midbrain [nTPM]":"3.7","Brain RNA - pons [nTPM]":"4.0","Brain RNA - spinal cord [nTPM]":"4.2","Brain RNA - thalamus [nTPM]":"3.9","Brain RNA - white matter [nTPM]":"6.3","Single Cell Type RNA - Adipocytes [nTPM]":"3.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.1","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"11.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"26.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.6","Single Cell Type RNA - Bipolar cells [nTPM]":"10.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"24.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"28.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.3","Single Cell Type RNA - dendritic cells [nTPM]":"2.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"29.4","Single Cell Type RNA - Ductal cells [nTPM]":"68.2","Single Cell Type RNA - Early spermatids [nTPM]":"31.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"40.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.4","Single Cell Type RNA - Endothelial cells [nTPM]":"4.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"84.8","Single Cell Type RNA - Erythroid cells [nTPM]":"37.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"138.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.1","Single Cell Type RNA - Fibroblasts [nTPM]":"7.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"31.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"43.7","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"11.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.7","Single Cell Type RNA - Hepatocytes [nTPM]":"649.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"32.5","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"24.2","Single Cell Type RNA - Langerhans cells [nTPM]":"6.4","Single Cell Type RNA - Late spermatids [nTPM]":"24.1","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"12.2","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"13.3","Single Cell Type RNA - Muller glia cells [nTPM]":"9.0","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"89.0","Single Cell Type RNA - Paneth cells [nTPM]":"18.1","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"7.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"218.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"270.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"42.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.9","Single Cell Type RNA - Spermatocytes [nTPM]":"7.4","Single Cell Type RNA - Spermatogonia [nTPM]":"2.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"35.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"6.5","Single Cell Type RNA - Theca cells [nTPM]":"15.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"39.4","Single Cell Type RNA - Urothelial cells [nTPM]":"131.2"},{"Gene":"SORL1","Gene synonym":["C11orf32","gp250","LR11","LRP9","SorLA","SorLA-1"],"Ensembl":"ENSG00000137642","Gene description":"Sortilin related receptor 1","Uniprot":["Q92673"],"Chromosome":"11","Position":"121452314-121633763","Protein class":["Disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":["Endocytosis","Transport"],"Molecular function":["Receptor"],"Disease involvement":["Alzheimer disease","Amyloidosis","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"79.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"387.8","Excitatory neurons":"247.4","Microglial cells":"404.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"125.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"125.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"142.8","Daudi":"68.7","OE19":"93.5","RT4":"102.1","U-698":"139.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011500","HPA031321"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"79000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB011500":"AB_443414","HPA031321":"AB_2673826"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.80e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.0","Tissue RNA - adrenal gland [nTPM]":"6.1","Tissue RNA - amygdala [nTPM]":"29.1","Tissue RNA - appendix [nTPM]":"24.4","Tissue RNA - basal ganglia [nTPM]":"39.1","Tissue RNA - bone marrow [nTPM]":"47.4","Tissue RNA - breast [nTPM]":"13.9","Tissue RNA - cerebellum [nTPM]":"49.5","Tissue RNA - cerebral cortex [nTPM]":"35.5","Tissue RNA - cervix [nTPM]":"44.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"17.3","Tissue RNA - duodenum [nTPM]":"11.6","Tissue RNA - endometrium 1 [nTPM]":"5.4","Tissue RNA - epididymis [nTPM]":"8.9","Tissue RNA - esophagus [nTPM]":"5.4","Tissue RNA - fallopian tube [nTPM]":"40.1","Tissue RNA - gallbladder [nTPM]":"7.3","Tissue RNA - heart muscle [nTPM]":"2.4","Tissue RNA - hippocampal formation [nTPM]":"33.8","Tissue RNA - hypothalamus [nTPM]":"39.7","Tissue RNA - kidney [nTPM]":"19.0","Tissue RNA - liver [nTPM]":"58.2","Tissue RNA - lung [nTPM]":"10.4","Tissue RNA - lymph node [nTPM]":"21.1","Tissue RNA - medulla oblongata [nTPM]":"40.3","Tissue RNA - midbrain [nTPM]":"46.8","Tissue RNA - ovary [nTPM]":"9.0","Tissue RNA - pancreas [nTPM]":"8.0","Tissue RNA - parathyroid gland [nTPM]":"10.4","Tissue RNA - pituitary gland [nTPM]":"16.8","Tissue RNA - placenta [nTPM]":"2.3","Tissue RNA - pons [nTPM]":"47.0","Tissue RNA - prostate [nTPM]":"20.8","Tissue RNA - rectum [nTPM]":"16.9","Tissue RNA - retina [nTPM]":"20.3","Tissue RNA - salivary gland [nTPM]":"21.8","Tissue RNA - seminal vesicle [nTPM]":"25.4","Tissue RNA - skeletal muscle [nTPM]":"1.7","Tissue RNA - skin 1 [nTPM]":"3.4","Tissue RNA - small intestine [nTPM]":"18.1","Tissue RNA - smooth muscle [nTPM]":"4.5","Tissue RNA - spinal cord [nTPM]":"45.3","Tissue RNA - spleen [nTPM]":"21.8","Tissue RNA - stomach 1 [nTPM]":"10.3","Tissue RNA - testis [nTPM]":"5.1","Tissue RNA - thalamus [nTPM]":"38.8","Tissue RNA - thymus [nTPM]":"17.0","Tissue RNA - thyroid gland [nTPM]":"13.5","Tissue RNA - tongue [nTPM]":"4.0","Tissue RNA - tonsil [nTPM]":"23.0","Tissue RNA - urinary bladder [nTPM]":"15.7","Tissue RNA - vagina [nTPM]":"6.6","Tissue RNA - white matter [nTPM]":"79.1","Cell RNA - A-431 [nTPM]":"1.3","Cell RNA - A549 [nTPM]":"8.1","Cell RNA - AF22 [nTPM]":"7.3","Cell RNA - AN3-CA [nTPM]":"1.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"7.4","Cell RNA - BJ [nTPM]":"0.4","Cell RNA - BJ hTERT+ [nTPM]":"2.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"11.9","Cell RNA - CAPAN-2 [nTPM]":"142.8","Cell RNA - Daudi [nTPM]":"68.7","Cell RNA - EFO-21 [nTPM]":"8.5","Cell RNA - fHDF\/TERT166 [nTPM]":"1.8","Cell RNA - GAMG [nTPM]":"10.5","Cell RNA - HaCaT [nTPM]":"47.4","Cell RNA - HAP1 [nTPM]":"9.1","Cell RNA - HBEC3-KT [nTPM]":"7.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"2.6","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"10.3","Cell RNA - Hep G2 [nTPM]":"16.8","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"29.6","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"7.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"25.8","Cell RNA - hTERT-RPE1 [nTPM]":"4.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"8.7","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"9.7","Cell RNA - MOLT-4 [nTPM]":"7.1","Cell RNA - NB-4 [nTPM]":"15.3","Cell RNA - NTERA-2 [nTPM]":"8.8","Cell RNA - OE19 [nTPM]":"93.5","Cell RNA - PC-3 [nTPM]":"10.8","Cell RNA - REH [nTPM]":"7.7","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"1.6","Cell RNA - RPTEC TERT1 [nTPM]":"15.8","Cell RNA - RT4 [nTPM]":"102.1","Cell RNA - SCLC-21H [nTPM]":"5.1","Cell RNA - SH-SY5Y [nTPM]":"1.5","Cell RNA - SiHa [nTPM]":"15.2","Cell RNA - SK-BR-3 [nTPM]":"21.5","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"16.0","Cell RNA - T-47d [nTPM]":"21.0","Cell RNA - THP-1 [nTPM]":"9.5","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"4.9","Cell RNA - U-2197 [nTPM]":"1.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"139.8","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"38.6","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"44.3","Blood RNA - classical monocyte [nTPM]":"15.9","Blood RNA - eosinophil [nTPM]":"59.1","Blood RNA - gdT-cell [nTPM]":"22.1","Blood RNA - intermediate monocyte [nTPM]":"6.9","Blood RNA - MAIT T-cell [nTPM]":"29.3","Blood RNA - memory B-cell [nTPM]":"1.9","Blood RNA - memory CD4 T-cell [nTPM]":"24.6","Blood RNA - memory CD8 T-cell [nTPM]":"20.0","Blood RNA - myeloid DC [nTPM]":"6.6","Blood RNA - naive B-cell [nTPM]":"5.1","Blood RNA - naive CD4 T-cell [nTPM]":"23.1","Blood RNA - naive CD8 T-cell [nTPM]":"20.8","Blood RNA - neutrophil [nTPM]":"125.7","Blood RNA - NK-cell [nTPM]":"20.9","Blood RNA - non-classical monocyte [nTPM]":"9.4","Blood RNA - plasmacytoid DC [nTPM]":"16.4","Blood RNA - T-reg [nTPM]":"19.3","Blood RNA - total PBMC [nTPM]":"21.2","Brain RNA - amygdala [nTPM]":"29.1","Brain RNA - basal ganglia [nTPM]":"39.1","Brain RNA - cerebellum [nTPM]":"49.5","Brain RNA - cerebral cortex [nTPM]":"35.5","Brain RNA - hippocampal formation [nTPM]":"33.8","Brain RNA - hypothalamus [nTPM]":"39.7","Brain RNA - medulla oblongata [nTPM]":"40.3","Brain RNA - midbrain [nTPM]":"46.8","Brain RNA - pons [nTPM]":"47.0","Brain RNA - spinal cord [nTPM]":"45.3","Brain RNA - thalamus [nTPM]":"38.8","Brain RNA - white matter [nTPM]":"79.1","Single Cell Type RNA - Adipocytes [nTPM]":"1.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.3","Single Cell Type RNA - Astrocytes [nTPM]":"160.9","Single Cell Type RNA - B-cells [nTPM]":"20.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"42.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"23.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.2","Single Cell Type RNA - Bipolar cells [nTPM]":"68.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"44.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"22.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"36.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"79.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"387.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"130.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"132.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"10.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"21.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.9","Single Cell Type RNA - Endothelial cells [nTPM]":"10.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.1","Single Cell Type RNA - Erythroid cells [nTPM]":"8.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"247.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"5.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.7","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"20.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"34.6","Single Cell Type RNA - Hepatocytes [nTPM]":"114.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"39.1","Single Cell Type RNA - Horizontal cells [nTPM]":"50.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"80.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"54.6","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"62.4","Single Cell Type RNA - Langerhans cells [nTPM]":"16.9","Single Cell Type RNA - Late spermatids [nTPM]":"5.0","Single Cell Type RNA - Leydig cells [nTPM]":"77.9","Single Cell Type RNA - Macrophages [nTPM]":"67.0","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"404.7","Single Cell Type RNA - monocytes [nTPM]":"97.5","Single Cell Type RNA - Muller glia cells [nTPM]":"28.0","Single Cell Type RNA - NK-cells [nTPM]":"146.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"74.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"86.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.4","Single Cell Type RNA - Paneth cells [nTPM]":"81.1","Single Cell Type RNA - Peritubular cells [nTPM]":"57.9","Single Cell Type RNA - Plasma cells [nTPM]":"28.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"36.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"168.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"31.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.3","Single Cell Type RNA - Spermatocytes [nTPM]":"2.9","Single Cell Type RNA - Spermatogonia [nTPM]":"18.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"60.2","Single Cell Type RNA - Theca cells [nTPM]":"32.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"42.2","Single Cell Type RNA - Urothelial cells [nTPM]":"33.4"},{"Gene":"SORT1","Gene synonym":["Gp95","NT3"],"Ensembl":"ENSG00000134243","Gene description":"Sortilin 1","Uniprot":["Q99523"],"Chromosome":"1","Position":"109309568-109397918","Protein class":["Disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Differentiation","Endocytosis","Osteogenesis","Transport"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"285.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Oligodendrocytes":"447.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"9.2","non-classical monocyte":"10.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006889","CAB011498"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":7170000,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Golgi apparatus","Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB011498":"AB_2192606","HPA006889":"AB_1080056"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.74e-6"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.23e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-3"},"Tissue RNA - adipose tissue [nTPM]":"48.2","Tissue RNA - adrenal gland [nTPM]":"11.3","Tissue RNA - amygdala [nTPM]":"71.0","Tissue RNA - appendix [nTPM]":"12.0","Tissue RNA - basal ganglia [nTPM]":"168.3","Tissue RNA - bone marrow [nTPM]":"21.4","Tissue RNA - breast [nTPM]":"25.1","Tissue RNA - cerebellum [nTPM]":"124.3","Tissue RNA - cerebral cortex [nTPM]":"114.2","Tissue RNA - cervix [nTPM]":"17.7","Tissue RNA - choroid plexus [nTPM]":"21.5","Tissue RNA - colon [nTPM]":"29.5","Tissue RNA - duodenum [nTPM]":"22.1","Tissue RNA - endometrium 1 [nTPM]":"24.7","Tissue RNA - epididymis [nTPM]":"139.8","Tissue RNA - esophagus [nTPM]":"41.5","Tissue RNA - fallopian tube [nTPM]":"27.5","Tissue RNA - gallbladder [nTPM]":"17.8","Tissue RNA - heart muscle [nTPM]":"64.7","Tissue RNA - hippocampal formation [nTPM]":"131.8","Tissue RNA - hypothalamus [nTPM]":"90.0","Tissue RNA - kidney [nTPM]":"38.7","Tissue RNA - liver [nTPM]":"6.5","Tissue RNA - lung [nTPM]":"37.4","Tissue RNA - lymph node [nTPM]":"2.8","Tissue RNA - medulla oblongata [nTPM]":"151.9","Tissue RNA - midbrain [nTPM]":"133.8","Tissue RNA - ovary [nTPM]":"6.1","Tissue RNA - pancreas [nTPM]":"17.5","Tissue RNA - parathyroid gland [nTPM]":"46.5","Tissue RNA - pituitary gland [nTPM]":"11.3","Tissue RNA - placenta [nTPM]":"44.8","Tissue RNA - pons [nTPM]":"153.1","Tissue RNA - prostate [nTPM]":"18.3","Tissue RNA - rectum [nTPM]":"26.9","Tissue RNA - retina [nTPM]":"40.0","Tissue RNA - salivary gland [nTPM]":"25.2","Tissue RNA - seminal vesicle [nTPM]":"44.0","Tissue RNA - skeletal muscle [nTPM]":"85.0","Tissue RNA - skin 1 [nTPM]":"19.0","Tissue RNA - small intestine [nTPM]":"21.9","Tissue RNA - smooth muscle [nTPM]":"27.8","Tissue RNA - spinal cord [nTPM]":"102.8","Tissue RNA - spleen [nTPM]":"10.2","Tissue RNA - stomach 1 [nTPM]":"18.2","Tissue RNA - testis [nTPM]":"43.5","Tissue RNA - thalamus [nTPM]":"118.0","Tissue RNA - thymus [nTPM]":"6.4","Tissue RNA - thyroid gland [nTPM]":"42.7","Tissue RNA - tongue [nTPM]":"71.8","Tissue RNA - tonsil [nTPM]":"10.3","Tissue RNA - urinary bladder [nTPM]":"16.9","Tissue RNA - vagina [nTPM]":"18.0","Tissue RNA - white matter [nTPM]":"285.6","Cell RNA - A-431 [nTPM]":"38.8","Cell RNA - A549 [nTPM]":"15.3","Cell RNA - AF22 [nTPM]":"37.5","Cell RNA - AN3-CA [nTPM]":"45.8","Cell RNA - ASC diff [nTPM]":"107.0","Cell RNA - ASC TERT1 [nTPM]":"21.2","Cell RNA - BEWO [nTPM]":"107.3","Cell RNA - BJ [nTPM]":"28.2","Cell RNA - BJ hTERT+ [nTPM]":"44.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"27.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"29.0","Cell RNA - CACO-2 [nTPM]":"39.8","Cell RNA - CAPAN-2 [nTPM]":"14.0","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"35.2","Cell RNA - fHDF\/TERT166 [nTPM]":"11.9","Cell RNA - GAMG [nTPM]":"19.9","Cell RNA - HaCaT [nTPM]":"9.4","Cell RNA - HAP1 [nTPM]":"44.7","Cell RNA - HBEC3-KT [nTPM]":"22.3","Cell RNA - HBF TERT88 [nTPM]":"38.9","Cell RNA - HDLM-2 [nTPM]":"1.1","Cell RNA - HEK 293 [nTPM]":"21.2","Cell RNA - HEL [nTPM]":"10.7","Cell RNA - HeLa [nTPM]":"23.5","Cell RNA - Hep G2 [nTPM]":"43.1","Cell RNA - HHSteC [nTPM]":"41.8","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"33.5","Cell RNA - HSkMC [nTPM]":"53.2","Cell RNA - hTCEpi [nTPM]":"3.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"33.3","Cell RNA - hTERT-HME1 [nTPM]":"7.3","Cell RNA - hTERT-RPE1 [nTPM]":"72.6","Cell RNA - HUVEC TERT2 [nTPM]":"4.2","Cell RNA - JURKAT [nTPM]":"31.7","Cell RNA - K-562 [nTPM]":"81.3","Cell RNA - Karpas-707 [nTPM]":"4.0","Cell RNA - LHCN-M2 [nTPM]":"38.7","Cell RNA - MCF7 [nTPM]":"41.1","Cell RNA - MOLT-4 [nTPM]":"27.9","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"14.1","Cell RNA - OE19 [nTPM]":"17.5","Cell RNA - PC-3 [nTPM]":"6.3","Cell RNA - REH [nTPM]":"30.7","Cell RNA - RH-30 [nTPM]":"87.9","Cell RNA - RPMI-8226 [nTPM]":"18.9","Cell RNA - RPTEC TERT1 [nTPM]":"52.0","Cell RNA - RT4 [nTPM]":"27.8","Cell RNA - SCLC-21H [nTPM]":"38.3","Cell RNA - SH-SY5Y [nTPM]":"21.8","Cell RNA - SiHa [nTPM]":"16.6","Cell RNA - SK-BR-3 [nTPM]":"109.3","Cell RNA - SK-MEL-30 [nTPM]":"120.6","Cell RNA - SuSa [nTPM]":"53.1","Cell RNA - T-47d [nTPM]":"46.1","Cell RNA - THP-1 [nTPM]":"6.7","Cell RNA - TIME [nTPM]":"1.1","Cell RNA - U-138 MG [nTPM]":"5.8","Cell RNA - U-2 OS [nTPM]":"21.7","Cell RNA - U-2197 [nTPM]":"1.0","Cell RNA - U-251 MG [nTPM]":"47.6","Cell RNA - U-266\/70 [nTPM]":"37.0","Cell RNA - U-266\/84 [nTPM]":"32.2","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"9.8","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"24.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"7.1","Blood RNA - eosinophil [nTPM]":"2.5","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"9.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"4.5","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"10.8","Blood RNA - plasmacytoid DC [nTPM]":"1.6","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"2.0","Brain RNA - amygdala [nTPM]":"71.0","Brain RNA - basal ganglia [nTPM]":"168.3","Brain RNA - cerebellum [nTPM]":"124.3","Brain RNA - cerebral cortex [nTPM]":"114.2","Brain RNA - hippocampal formation [nTPM]":"131.8","Brain RNA - hypothalamus [nTPM]":"90.0","Brain RNA - medulla oblongata [nTPM]":"151.9","Brain RNA - midbrain [nTPM]":"133.8","Brain RNA - pons [nTPM]":"153.1","Brain RNA - spinal cord [nTPM]":"102.8","Brain RNA - thalamus [nTPM]":"118.0","Brain RNA - white matter [nTPM]":"285.6","Single Cell Type RNA - Adipocytes [nTPM]":"10.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"47.9","Single Cell Type RNA - Astrocytes [nTPM]":"54.5","Single Cell Type RNA - B-cells [nTPM]":"1.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"14.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"27.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"98.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"20.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"75.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"30.6","Single Cell Type RNA - dendritic cells [nTPM]":"3.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"70.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"23.9","Single Cell Type RNA - Early spermatids [nTPM]":"65.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"33.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.2","Single Cell Type RNA - Endothelial cells [nTPM]":"15.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.8","Single Cell Type RNA - Erythroid cells [nTPM]":"4.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"87.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"30.2","Single Cell Type RNA - Fibroblasts [nTPM]":"9.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"34.9","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"10.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"22.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.1","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"56.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"27.7","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"38.7","Single Cell Type RNA - Langerhans cells [nTPM]":"9.9","Single Cell Type RNA - Late spermatids [nTPM]":"79.7","Single Cell Type RNA - Leydig cells [nTPM]":"8.7","Single Cell Type RNA - Macrophages [nTPM]":"34.6","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"78.7","Single Cell Type RNA - monocytes [nTPM]":"37.7","Single Cell Type RNA - Muller glia cells [nTPM]":"21.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"48.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"447.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"25.6","Single Cell Type RNA - Paneth cells [nTPM]":"23.2","Single Cell Type RNA - Peritubular cells [nTPM]":"49.7","Single Cell Type RNA - Plasma cells [nTPM]":"1.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"64.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"50.7","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"25.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"53.6","Single Cell Type RNA - Spermatocytes [nTPM]":"46.3","Single Cell Type RNA - Spermatogonia [nTPM]":"21.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"36.8","Single Cell Type RNA - T-cells [nTPM]":"2.1","Single Cell Type RNA - Theca cells [nTPM]":"1.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"28.3","Single Cell Type RNA - Urothelial cells [nTPM]":"10.8"},{"Gene":"SPAST","Gene synonym":["ADPSP","FSP2","KIAA1083","SPG4"],"Ensembl":"ENSG00000021574","Gene description":"Spastin","Uniprot":["Q9UBP0"],"Chromosome":"2","Position":"32063556-32157637","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cell cycle","Cell division","Differentiation","Neurogenesis"],"Molecular function":["Allosteric enzyme","Developmental protein","Isomerase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"55.2","Oligodendrocyte precursor cells":"59.3","Oligodendrocytes":"62.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017311"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA017311":"AB_1857415"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.62e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.15e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.8","Tissue RNA - adrenal gland [nTPM]":"5.9","Tissue RNA - amygdala [nTPM]":"9.0","Tissue RNA - appendix [nTPM]":"7.2","Tissue RNA - basal ganglia [nTPM]":"12.7","Tissue RNA - bone marrow [nTPM]":"9.9","Tissue RNA - breast [nTPM]":"6.2","Tissue RNA - cerebellum [nTPM]":"10.8","Tissue RNA - cerebral cortex [nTPM]":"12.9","Tissue RNA - cervix [nTPM]":"8.6","Tissue RNA - choroid plexus [nTPM]":"1.6","Tissue RNA - colon [nTPM]":"7.1","Tissue RNA - duodenum [nTPM]":"7.4","Tissue RNA - endometrium 1 [nTPM]":"7.7","Tissue RNA - epididymis [nTPM]":"5.0","Tissue RNA - esophagus [nTPM]":"6.9","Tissue RNA - fallopian tube [nTPM]":"6.5","Tissue RNA - gallbladder [nTPM]":"6.5","Tissue RNA - heart muscle [nTPM]":"3.9","Tissue RNA - hippocampal formation [nTPM]":"9.0","Tissue RNA - hypothalamus [nTPM]":"10.6","Tissue RNA - kidney [nTPM]":"5.9","Tissue RNA - liver [nTPM]":"9.6","Tissue RNA - lung [nTPM]":"6.3","Tissue RNA - lymph node [nTPM]":"9.7","Tissue RNA - medulla oblongata [nTPM]":"10.8","Tissue RNA - midbrain [nTPM]":"11.2","Tissue RNA - ovary [nTPM]":"9.1","Tissue RNA - pancreas [nTPM]":"5.3","Tissue RNA - parathyroid gland [nTPM]":"6.2","Tissue RNA - pituitary gland [nTPM]":"4.4","Tissue RNA - placenta [nTPM]":"6.8","Tissue RNA - pons [nTPM]":"10.5","Tissue RNA - prostate [nTPM]":"6.3","Tissue RNA - rectum [nTPM]":"7.5","Tissue RNA - retina [nTPM]":"6.9","Tissue RNA - salivary gland [nTPM]":"4.2","Tissue RNA - seminal vesicle [nTPM]":"5.3","Tissue RNA - skeletal muscle [nTPM]":"7.8","Tissue RNA - skin 1 [nTPM]":"7.4","Tissue RNA - small intestine [nTPM]":"8.0","Tissue RNA - smooth muscle [nTPM]":"7.3","Tissue RNA - spinal cord [nTPM]":"11.6","Tissue RNA - spleen [nTPM]":"7.0","Tissue RNA - stomach 1 [nTPM]":"6.3","Tissue RNA - testis [nTPM]":"9.8","Tissue RNA - thalamus [nTPM]":"10.7","Tissue RNA - thymus [nTPM]":"14.1","Tissue RNA - thyroid gland [nTPM]":"8.5","Tissue RNA - tongue [nTPM]":"10.0","Tissue RNA - tonsil [nTPM]":"9.2","Tissue RNA - urinary bladder [nTPM]":"7.3","Tissue RNA - vagina [nTPM]":"4.4","Tissue RNA - white matter [nTPM]":"13.9","Cell RNA - A-431 [nTPM]":"17.5","Cell RNA - A549 [nTPM]":"12.2","Cell RNA - AF22 [nTPM]":"19.7","Cell RNA - AN3-CA [nTPM]":"19.5","Cell RNA - ASC diff [nTPM]":"12.0","Cell RNA - ASC TERT1 [nTPM]":"14.2","Cell RNA - BEWO [nTPM]":"17.8","Cell RNA - BJ [nTPM]":"9.4","Cell RNA - BJ hTERT+ [nTPM]":"13.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.6","Cell RNA - CACO-2 [nTPM]":"16.9","Cell RNA - CAPAN-2 [nTPM]":"14.8","Cell RNA - Daudi [nTPM]":"30.2","Cell RNA - EFO-21 [nTPM]":"8.5","Cell RNA - fHDF\/TERT166 [nTPM]":"13.1","Cell RNA - GAMG [nTPM]":"14.2","Cell RNA - HaCaT [nTPM]":"12.0","Cell RNA - HAP1 [nTPM]":"19.5","Cell RNA - HBEC3-KT [nTPM]":"9.6","Cell RNA - HBF TERT88 [nTPM]":"11.9","Cell RNA - HDLM-2 [nTPM]":"20.7","Cell RNA - HEK 293 [nTPM]":"11.8","Cell RNA - HEL [nTPM]":"33.3","Cell RNA - HeLa [nTPM]":"6.0","Cell RNA - Hep G2 [nTPM]":"20.5","Cell RNA - HHSteC [nTPM]":"11.0","Cell RNA - HL-60 [nTPM]":"23.2","Cell RNA - HMC-1 [nTPM]":"22.4","Cell RNA - HSkMC [nTPM]":"7.9","Cell RNA - hTCEpi [nTPM]":"12.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.4","Cell RNA - hTERT-HME1 [nTPM]":"11.6","Cell RNA - hTERT-RPE1 [nTPM]":"11.7","Cell RNA - HUVEC TERT2 [nTPM]":"21.5","Cell RNA - JURKAT [nTPM]":"9.6","Cell RNA - K-562 [nTPM]":"27.6","Cell RNA - Karpas-707 [nTPM]":"10.0","Cell RNA - LHCN-M2 [nTPM]":"10.7","Cell RNA - MCF7 [nTPM]":"7.4","Cell RNA - MOLT-4 [nTPM]":"37.8","Cell RNA - NB-4 [nTPM]":"19.4","Cell RNA - NTERA-2 [nTPM]":"20.5","Cell RNA - OE19 [nTPM]":"19.2","Cell RNA - PC-3 [nTPM]":"7.1","Cell RNA - REH [nTPM]":"19.8","Cell RNA - RH-30 [nTPM]":"27.9","Cell RNA - RPMI-8226 [nTPM]":"19.5","Cell RNA - RPTEC TERT1 [nTPM]":"13.0","Cell RNA - RT4 [nTPM]":"10.7","Cell RNA - SCLC-21H [nTPM]":"27.9","Cell RNA - SH-SY5Y [nTPM]":"29.9","Cell RNA - SiHa [nTPM]":"16.0","Cell RNA - SK-BR-3 [nTPM]":"13.2","Cell RNA - SK-MEL-30 [nTPM]":"15.9","Cell RNA - SuSa [nTPM]":"16.0","Cell RNA - T-47d [nTPM]":"8.7","Cell RNA - THP-1 [nTPM]":"15.8","Cell RNA - TIME [nTPM]":"18.8","Cell RNA - U-138 MG [nTPM]":"10.6","Cell RNA - U-2 OS [nTPM]":"16.2","Cell RNA - U-2197 [nTPM]":"9.5","Cell RNA - U-251 MG [nTPM]":"11.1","Cell RNA - U-266\/70 [nTPM]":"14.7","Cell RNA - U-266\/84 [nTPM]":"29.7","Cell RNA - U-698 [nTPM]":"23.8","Cell RNA - U-87 MG [nTPM]":"11.6","Cell RNA - U-937 [nTPM]":"19.9","Cell RNA - WM-115 [nTPM]":"13.0","Blood RNA - basophil [nTPM]":"1.8","Blood RNA - classical monocyte [nTPM]":"3.5","Blood RNA - eosinophil [nTPM]":"3.8","Blood RNA - gdT-cell [nTPM]":"1.8","Blood RNA - intermediate monocyte [nTPM]":"4.9","Blood RNA - MAIT T-cell [nTPM]":"2.5","Blood RNA - memory B-cell [nTPM]":"2.4","Blood RNA - memory CD4 T-cell [nTPM]":"2.8","Blood RNA - memory CD8 T-cell [nTPM]":"2.9","Blood RNA - myeloid DC [nTPM]":"3.9","Blood RNA - naive B-cell [nTPM]":"1.9","Blood RNA - naive CD4 T-cell [nTPM]":"2.9","Blood RNA - naive CD8 T-cell [nTPM]":"3.0","Blood RNA - neutrophil [nTPM]":"5.3","Blood RNA - NK-cell [nTPM]":"3.9","Blood RNA - non-classical monocyte [nTPM]":"3.8","Blood RNA - plasmacytoid DC [nTPM]":"1.7","Blood RNA - T-reg [nTPM]":"4.2","Blood RNA - total PBMC [nTPM]":"2.5","Brain RNA - amygdala [nTPM]":"9.0","Brain RNA - basal ganglia [nTPM]":"12.7","Brain RNA - cerebellum [nTPM]":"10.8","Brain RNA - cerebral cortex [nTPM]":"12.9","Brain RNA - hippocampal formation [nTPM]":"9.0","Brain RNA - hypothalamus [nTPM]":"10.6","Brain RNA - medulla oblongata [nTPM]":"10.8","Brain RNA - midbrain [nTPM]":"11.2","Brain RNA - pons [nTPM]":"10.5","Brain RNA - spinal cord [nTPM]":"11.6","Brain RNA - thalamus [nTPM]":"10.7","Brain RNA - white matter [nTPM]":"13.9","Single Cell Type RNA - Adipocytes [nTPM]":"15.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.4","Single Cell Type RNA - Astrocytes [nTPM]":"26.4","Single Cell Type RNA - B-cells [nTPM]":"12.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"15.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"7.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.6","Single Cell Type RNA - dendritic cells [nTPM]":"21.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.6","Single Cell Type RNA - Early spermatids [nTPM]":"4.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.8","Single Cell Type RNA - Endothelial cells [nTPM]":"11.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.8","Single Cell Type RNA - Erythroid cells [nTPM]":"10.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"38.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.4","Single Cell Type RNA - Fibroblasts [nTPM]":"8.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.7","Single Cell Type RNA - granulocytes [nTPM]":"10.1","Single Cell Type RNA - Granulosa cells [nTPM]":"16.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"12.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.7","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"55.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.8","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"17.5","Single Cell Type RNA - Langerhans cells [nTPM]":"9.9","Single Cell Type RNA - Late spermatids [nTPM]":"8.5","Single Cell Type RNA - Leydig cells [nTPM]":"8.7","Single Cell Type RNA - Macrophages [nTPM]":"17.6","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"36.5","Single Cell Type RNA - monocytes [nTPM]":"21.1","Single Cell Type RNA - Muller glia cells [nTPM]":"7.9","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"59.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"62.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.4","Single Cell Type RNA - Paneth cells [nTPM]":"9.8","Single Cell Type RNA - Peritubular cells [nTPM]":"10.1","Single Cell Type RNA - Plasma cells [nTPM]":"12.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.9","Single Cell Type RNA - Spermatocytes [nTPM]":"16.7","Single Cell Type RNA - Spermatogonia [nTPM]":"21.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.1","Single Cell Type RNA - T-cells [nTPM]":"13.3","Single Cell Type RNA - Theca cells [nTPM]":"10.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.4","Single Cell Type RNA - Urothelial cells [nTPM]":"7.2"},{"Gene":"SPATA5","Gene synonym":["AFG2","SPAF"],"Ensembl":"ENSG00000145375","Gene description":"Spermatogenesis associated 5","Uniprot":["Q8NB90"],"Chromosome":"4","Position":"122923070-123319433","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":["Chaperone","Developmental protein","Hydrolase"],"Disease involvement":["Deafness","Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"207.9","Inhibitory neurons":"59.0","Microglial cells":"104.0","Oligodendrocyte precursor cells":"79.9","Oligodendrocytes":"91.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036450","HPA036451"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 23: Spermatids - Flagellum & Golgi organization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA036450":"AB_2675131","HPA036451":"AB_10670107"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.3","Tissue RNA - adrenal gland [nTPM]":"0.8","Tissue RNA - amygdala [nTPM]":"0.8","Tissue RNA - appendix [nTPM]":"0.9","Tissue RNA - basal ganglia [nTPM]":"1.1","Tissue RNA - bone marrow [nTPM]":"1.4","Tissue RNA - breast [nTPM]":"1.6","Tissue RNA - cerebellum [nTPM]":"2.3","Tissue RNA - cerebral cortex [nTPM]":"1.0","Tissue RNA - cervix [nTPM]":"1.3","Tissue RNA - choroid plexus [nTPM]":"1.2","Tissue RNA - colon [nTPM]":"1.0","Tissue RNA - duodenum [nTPM]":"0.6","Tissue RNA - endometrium 1 [nTPM]":"1.3","Tissue RNA - epididymis [nTPM]":"0.8","Tissue RNA - esophagus [nTPM]":"1.0","Tissue RNA - fallopian tube [nTPM]":"1.0","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"0.9","Tissue RNA - hippocampal formation [nTPM]":"0.6","Tissue RNA - hypothalamus [nTPM]":"1.2","Tissue RNA - kidney [nTPM]":"1.1","Tissue RNA - liver [nTPM]":"1.1","Tissue RNA - lung [nTPM]":"0.9","Tissue RNA - lymph node [nTPM]":"1.2","Tissue RNA - medulla oblongata [nTPM]":"1.2","Tissue RNA - midbrain [nTPM]":"1.1","Tissue RNA - ovary [nTPM]":"1.2","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"1.5","Tissue RNA - pituitary gland [nTPM]":"0.7","Tissue RNA - placenta [nTPM]":"1.4","Tissue RNA - pons [nTPM]":"1.2","Tissue RNA - prostate [nTPM]":"1.1","Tissue RNA - rectum [nTPM]":"1.2","Tissue RNA - retina [nTPM]":"2.2","Tissue RNA - salivary gland [nTPM]":"1.0","Tissue RNA - seminal vesicle [nTPM]":"1.1","Tissue RNA - skeletal muscle [nTPM]":"1.3","Tissue RNA - skin 1 [nTPM]":"1.2","Tissue RNA - small intestine [nTPM]":"0.7","Tissue RNA - smooth muscle [nTPM]":"1.3","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"1.3","Tissue RNA - stomach 1 [nTPM]":"2.3","Tissue RNA - testis [nTPM]":"3.6","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"2.0","Tissue RNA - thyroid gland [nTPM]":"1.5","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"1.2","Tissue RNA - urinary bladder [nTPM]":"1.0","Tissue RNA - vagina [nTPM]":"1.1","Tissue RNA - white matter [nTPM]":"1.3","Cell RNA - A-431 [nTPM]":"2.3","Cell RNA - A549 [nTPM]":"3.2","Cell RNA - AF22 [nTPM]":"2.9","Cell RNA - AN3-CA [nTPM]":"7.1","Cell RNA - ASC diff [nTPM]":"2.4","Cell RNA - ASC TERT1 [nTPM]":"1.7","Cell RNA - BEWO [nTPM]":"1.9","Cell RNA - BJ [nTPM]":"4.0","Cell RNA - BJ hTERT+ [nTPM]":"1.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.3","Cell RNA - CACO-2 [nTPM]":"1.5","Cell RNA - CAPAN-2 [nTPM]":"3.2","Cell RNA - Daudi [nTPM]":"3.7","Cell RNA - EFO-21 [nTPM]":"2.4","Cell RNA - fHDF\/TERT166 [nTPM]":"2.4","Cell RNA - GAMG [nTPM]":"2.4","Cell RNA - HaCaT [nTPM]":"2.0","Cell RNA - HAP1 [nTPM]":"5.0","Cell RNA - HBEC3-KT [nTPM]":"2.2","Cell RNA - HBF TERT88 [nTPM]":"5.6","Cell RNA - HDLM-2 [nTPM]":"6.2","Cell RNA - HEK 293 [nTPM]":"0.9","Cell RNA - HEL [nTPM]":"3.8","Cell RNA - HeLa [nTPM]":"5.7","Cell RNA - Hep G2 [nTPM]":"2.5","Cell RNA - HHSteC [nTPM]":"1.1","Cell RNA - HL-60 [nTPM]":"5.2","Cell RNA - HMC-1 [nTPM]":"4.0","Cell RNA - HSkMC [nTPM]":"1.2","Cell RNA - hTCEpi [nTPM]":"1.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.8","Cell RNA - hTERT-HME1 [nTPM]":"3.3","Cell RNA - hTERT-RPE1 [nTPM]":"1.7","Cell RNA - HUVEC TERT2 [nTPM]":"3.4","Cell RNA - JURKAT [nTPM]":"2.4","Cell RNA - K-562 [nTPM]":"7.7","Cell RNA - Karpas-707 [nTPM]":"6.2","Cell RNA - LHCN-M2 [nTPM]":"4.6","Cell RNA - MCF7 [nTPM]":"2.4","Cell RNA - MOLT-4 [nTPM]":"10.1","Cell RNA - NB-4 [nTPM]":"3.2","Cell RNA - NTERA-2 [nTPM]":"2.1","Cell RNA - OE19 [nTPM]":"3.6","Cell RNA - PC-3 [nTPM]":"1.3","Cell RNA - REH [nTPM]":"3.3","Cell RNA - RH-30 [nTPM]":"7.2","Cell RNA - RPMI-8226 [nTPM]":"2.4","Cell RNA - RPTEC TERT1 [nTPM]":"1.9","Cell RNA - RT4 [nTPM]":"1.9","Cell RNA - SCLC-21H [nTPM]":"4.8","Cell RNA - SH-SY5Y [nTPM]":"3.1","Cell RNA - SiHa [nTPM]":"3.2","Cell RNA - SK-BR-3 [nTPM]":"2.3","Cell RNA - SK-MEL-30 [nTPM]":"1.7","Cell RNA - SuSa [nTPM]":"4.2","Cell RNA - T-47d [nTPM]":"2.2","Cell RNA - THP-1 [nTPM]":"2.0","Cell RNA - TIME [nTPM]":"2.6","Cell RNA - U-138 MG [nTPM]":"6.9","Cell RNA - U-2 OS [nTPM]":"5.2","Cell RNA - U-2197 [nTPM]":"4.6","Cell RNA - U-251 MG [nTPM]":"4.2","Cell RNA - U-266\/70 [nTPM]":"3.9","Cell RNA - U-266\/84 [nTPM]":"5.0","Cell RNA - U-698 [nTPM]":"3.3","Cell RNA - U-87 MG [nTPM]":"3.3","Cell RNA - U-937 [nTPM]":"4.4","Cell RNA - WM-115 [nTPM]":"6.2","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"0.8","Brain RNA - basal ganglia [nTPM]":"1.1","Brain RNA - cerebellum [nTPM]":"2.3","Brain RNA - cerebral cortex [nTPM]":"1.0","Brain RNA - hippocampal formation [nTPM]":"0.6","Brain RNA - hypothalamus [nTPM]":"1.2","Brain RNA - medulla oblongata [nTPM]":"1.2","Brain RNA - midbrain [nTPM]":"1.1","Brain RNA - pons [nTPM]":"1.2","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"1.3","Single Cell Type RNA - Adipocytes [nTPM]":"10.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.0","Single Cell Type RNA - Astrocytes [nTPM]":"34.6","Single Cell Type RNA - B-cells [nTPM]":"9.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"6.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"7.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.1","Single Cell Type RNA - dendritic cells [nTPM]":"6.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.1","Single Cell Type RNA - Early spermatids [nTPM]":"207.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.6","Single Cell Type RNA - Endothelial cells [nTPM]":"8.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"11.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"48.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.3","Single Cell Type RNA - Fibroblasts [nTPM]":"5.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.2","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"8.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.2","Single Cell Type RNA - Hepatocytes [nTPM]":"3.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.5","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"59.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.1","Single Cell Type RNA - Langerhans cells [nTPM]":"5.3","Single Cell Type RNA - Late spermatids [nTPM]":"25.0","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"5.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"104.0","Single Cell Type RNA - monocytes [nTPM]":"1.8","Single Cell Type RNA - Muller glia cells [nTPM]":"4.0","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"79.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"91.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.2","Single Cell Type RNA - Paneth cells [nTPM]":"2.1","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"10.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.6","Single Cell Type RNA - Spermatocytes [nTPM]":"14.7","Single Cell Type RNA - Spermatogonia [nTPM]":"10.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.2","Single Cell Type RNA - T-cells [nTPM]":"9.9","Single Cell Type RNA - Theca cells [nTPM]":"4.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.1","Single Cell Type RNA - Urothelial cells [nTPM]":"3.0"},{"Gene":"SPEG","Gene synonym":["APEG1","BPEG","KIAA1297","MGC12676","MYLK6","SPEGalpha","SPEGbeta"],"Ensembl":"ENSG00000072195","Gene description":"Striated muscle enriched protein kinase","Uniprot":["Q15772"],"Chromosome":"2","Position":"219434843-219493629","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Differentiation"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"174.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"45.7","Cardiomyocytes":"61.5","Late spermatids":"39.6","Sertoli cells":"46.0","Smooth muscle cells":"32.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTERT-RPE1":"45.9","U-87 MG":"23.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018904"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA018904":"AB_1844924"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.66e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-3"},"Tissue RNA - adipose tissue [nTPM]":"16.1","Tissue RNA - adrenal gland [nTPM]":"6.8","Tissue RNA - amygdala [nTPM]":"16.8","Tissue RNA - appendix [nTPM]":"7.7","Tissue RNA - basal ganglia [nTPM]":"18.7","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"15.3","Tissue RNA - cerebellum [nTPM]":"15.5","Tissue RNA - cerebral cortex [nTPM]":"20.7","Tissue RNA - cervix [nTPM]":"75.5","Tissue RNA - choroid plexus [nTPM]":"9.7","Tissue RNA - colon [nTPM]":"174.8","Tissue RNA - duodenum [nTPM]":"5.3","Tissue RNA - endometrium 1 [nTPM]":"89.5","Tissue RNA - epididymis [nTPM]":"6.2","Tissue RNA - esophagus [nTPM]":"15.6","Tissue RNA - fallopian tube [nTPM]":"70.0","Tissue RNA - gallbladder [nTPM]":"7.3","Tissue RNA - heart muscle [nTPM]":"48.5","Tissue RNA - hippocampal formation [nTPM]":"19.8","Tissue RNA - hypothalamus [nTPM]":"14.5","Tissue RNA - kidney [nTPM]":"4.1","Tissue RNA - liver [nTPM]":"1.3","Tissue RNA - lung [nTPM]":"8.7","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"16.1","Tissue RNA - midbrain [nTPM]":"15.8","Tissue RNA - ovary [nTPM]":"21.9","Tissue RNA - pancreas [nTPM]":"3.4","Tissue RNA - parathyroid gland [nTPM]":"4.4","Tissue RNA - pituitary gland [nTPM]":"34.3","Tissue RNA - placenta [nTPM]":"4.5","Tissue RNA - pons [nTPM]":"14.6","Tissue RNA - prostate [nTPM]":"58.8","Tissue RNA - rectum [nTPM]":"3.8","Tissue RNA - retina [nTPM]":"1.0","Tissue RNA - salivary gland [nTPM]":"10.0","Tissue RNA - seminal vesicle [nTPM]":"25.5","Tissue RNA - skeletal muscle [nTPM]":"118.0","Tissue RNA - skin 1 [nTPM]":"7.8","Tissue RNA - small intestine [nTPM]":"31.9","Tissue RNA - smooth muscle [nTPM]":"23.1","Tissue RNA - spinal cord [nTPM]":"15.3","Tissue RNA - spleen [nTPM]":"2.4","Tissue RNA - stomach 1 [nTPM]":"48.1","Tissue RNA - testis [nTPM]":"5.4","Tissue RNA - thalamus [nTPM]":"15.3","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"5.9","Tissue RNA - tongue [nTPM]":"21.7","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"87.7","Tissue RNA - vagina [nTPM]":"42.1","Tissue RNA - white matter [nTPM]":"15.6","Cell RNA - A-431 [nTPM]":"6.1","Cell RNA - A549 [nTPM]":"0.5","Cell RNA - AF22 [nTPM]":"3.1","Cell RNA - AN3-CA [nTPM]":"4.9","Cell RNA - ASC diff [nTPM]":"1.6","Cell RNA - ASC TERT1 [nTPM]":"4.7","Cell RNA - BEWO [nTPM]":"1.8","Cell RNA - BJ [nTPM]":"13.1","Cell RNA - BJ hTERT+ [nTPM]":"8.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.4","Cell RNA - CACO-2 [nTPM]":"4.5","Cell RNA - CAPAN-2 [nTPM]":"1.9","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"4.5","Cell RNA - fHDF\/TERT166 [nTPM]":"9.7","Cell RNA - GAMG [nTPM]":"4.3","Cell RNA - HaCaT [nTPM]":"7.2","Cell RNA - HAP1 [nTPM]":"2.5","Cell RNA - HBEC3-KT [nTPM]":"3.1","Cell RNA - HBF TERT88 [nTPM]":"3.4","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.7","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"6.1","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"2.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"13.2","Cell RNA - hTCEpi [nTPM]":"4.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.8","Cell RNA - hTERT-HME1 [nTPM]":"1.9","Cell RNA - hTERT-RPE1 [nTPM]":"45.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"3.2","Cell RNA - K-562 [nTPM]":"3.5","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"6.1","Cell RNA - MCF7 [nTPM]":"1.6","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"18.8","Cell RNA - NTERA-2 [nTPM]":"6.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"2.4","Cell RNA - REH [nTPM]":"2.8","Cell RNA - RH-30 [nTPM]":"7.0","Cell RNA - RPMI-8226 [nTPM]":"1.1","Cell RNA - RPTEC TERT1 [nTPM]":"8.5","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"3.4","Cell RNA - SH-SY5Y [nTPM]":"15.1","Cell RNA - SiHa [nTPM]":"0.6","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"14.3","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"20.6","Cell RNA - U-2 OS [nTPM]":"21.3","Cell RNA - U-2197 [nTPM]":"2.4","Cell RNA - U-251 MG [nTPM]":"21.1","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"23.3","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"1.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"16.8","Brain RNA - basal ganglia [nTPM]":"18.7","Brain RNA - cerebellum [nTPM]":"15.5","Brain RNA - cerebral cortex [nTPM]":"20.7","Brain RNA - hippocampal formation [nTPM]":"19.8","Brain RNA - hypothalamus [nTPM]":"14.5","Brain RNA - medulla oblongata [nTPM]":"16.1","Brain RNA - midbrain [nTPM]":"15.8","Brain RNA - pons [nTPM]":"14.6","Brain RNA - spinal cord [nTPM]":"15.3","Brain RNA - thalamus [nTPM]":"15.3","Brain RNA - white matter [nTPM]":"15.6","Single Cell Type RNA - Adipocytes [nTPM]":"2.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.2","Single Cell Type RNA - Astrocytes [nTPM]":"45.7","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"5.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"61.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.6","Single Cell Type RNA - dendritic cells [nTPM]":"1.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.5","Single Cell Type RNA - Early spermatids [nTPM]":"21.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.6","Single Cell Type RNA - Endothelial cells [nTPM]":"2.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"20.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.9","Single Cell Type RNA - Fibroblasts [nTPM]":"10.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.7","Single Cell Type RNA - Hepatocytes [nTPM]":"3.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.1","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"5.6","Single Cell Type RNA - Langerhans cells [nTPM]":"1.9","Single Cell Type RNA - Late spermatids [nTPM]":"39.6","Single Cell Type RNA - Leydig cells [nTPM]":"10.5","Single Cell Type RNA - Macrophages [nTPM]":"1.6","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"1.4","Single Cell Type RNA - Muller glia cells [nTPM]":"8.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"3.2","Single Cell Type RNA - Peritubular cells [nTPM]":"18.8","Single Cell Type RNA - Plasma cells [nTPM]":"0.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.9","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.4","Single Cell Type RNA - Spermatocytes [nTPM]":"11.6","Single Cell Type RNA - Spermatogonia [nTPM]":"3.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - T-cells [nTPM]":"1.2","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.5","Single Cell Type RNA - Urothelial cells [nTPM]":"5.3"},{"Gene":"SPG7","Gene synonym":["CAR","CMAR","SPG5C"],"Ensembl":"ENSG00000197912","Gene description":"SPG7 matrix AAA peptidase subunit, paraplegin","Uniprot":["Q9UQ90"],"Chromosome":"16","Position":"89490719-89557766","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration","Osteogenesis imperfecta"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.22e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.91e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.25e-4"},"Tissue RNA - adipose tissue [nTPM]":"29.8","Tissue RNA - adrenal gland [nTPM]":"44.8","Tissue RNA - amygdala [nTPM]":"19.3","Tissue RNA - appendix [nTPM]":"7.0","Tissue RNA - basal ganglia [nTPM]":"18.8","Tissue RNA - bone marrow [nTPM]":"8.2","Tissue RNA - breast [nTPM]":"27.9","Tissue RNA - cerebellum [nTPM]":"21.3","Tissue RNA - cerebral cortex [nTPM]":"28.6","Tissue RNA - cervix [nTPM]":"31.5","Tissue RNA - choroid plexus [nTPM]":"18.5","Tissue RNA - colon [nTPM]":"33.3","Tissue RNA - duodenum [nTPM]":"9.9","Tissue RNA - endometrium 1 [nTPM]":"31.8","Tissue RNA - epididymis [nTPM]":"4.0","Tissue RNA - esophagus [nTPM]":"28.2","Tissue RNA - fallopian tube [nTPM]":"26.4","Tissue RNA - gallbladder [nTPM]":"6.8","Tissue RNA - heart muscle [nTPM]":"52.3","Tissue RNA - hippocampal formation [nTPM]":"19.4","Tissue RNA - hypothalamus [nTPM]":"18.3","Tissue RNA - kidney [nTPM]":"32.4","Tissue RNA - liver [nTPM]":"47.0","Tissue RNA - lung [nTPM]":"24.9","Tissue RNA - lymph node [nTPM]":"8.9","Tissue RNA - medulla oblongata [nTPM]":"19.7","Tissue RNA - midbrain [nTPM]":"18.6","Tissue RNA - ovary [nTPM]":"39.0","Tissue RNA - pancreas [nTPM]":"31.9","Tissue RNA - parathyroid gland [nTPM]":"13.8","Tissue RNA - pituitary gland [nTPM]":"38.7","Tissue RNA - placenta [nTPM]":"5.9","Tissue RNA - pons [nTPM]":"20.3","Tissue RNA - prostate [nTPM]":"31.2","Tissue RNA - rectum [nTPM]":"8.1","Tissue RNA - retina [nTPM]":"9.9","Tissue RNA - salivary gland [nTPM]":"29.0","Tissue RNA - seminal vesicle [nTPM]":"9.7","Tissue RNA - skeletal muscle [nTPM]":"56.7","Tissue RNA - skin 1 [nTPM]":"31.3","Tissue RNA - small intestine [nTPM]":"35.5","Tissue RNA - smooth muscle [nTPM]":"9.0","Tissue RNA - spinal cord [nTPM]":"16.9","Tissue RNA - spleen [nTPM]":"34.1","Tissue RNA - stomach 1 [nTPM]":"31.1","Tissue RNA - testis [nTPM]":"31.9","Tissue RNA - thalamus [nTPM]":"18.7","Tissue RNA - thymus [nTPM]":"10.5","Tissue RNA - thyroid gland [nTPM]":"53.1","Tissue RNA - tongue [nTPM]":"31.0","Tissue RNA - tonsil [nTPM]":"8.0","Tissue RNA - urinary bladder [nTPM]":"30.1","Tissue RNA - vagina [nTPM]":"26.9","Tissue RNA - white matter [nTPM]":"20.0","Cell RNA - A-431 [nTPM]":"11.5","Cell RNA - A549 [nTPM]":"28.3","Cell RNA - AF22 [nTPM]":"17.3","Cell RNA - AN3-CA [nTPM]":"26.6","Cell RNA - ASC diff [nTPM]":"33.2","Cell RNA - ASC TERT1 [nTPM]":"24.2","Cell RNA - BEWO [nTPM]":"10.9","Cell RNA - BJ [nTPM]":"27.3","Cell RNA - BJ hTERT+ [nTPM]":"24.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.4","Cell RNA - CACO-2 [nTPM]":"23.0","Cell RNA - CAPAN-2 [nTPM]":"22.3","Cell RNA - Daudi [nTPM]":"16.5","Cell RNA - EFO-21 [nTPM]":"32.5","Cell RNA - fHDF\/TERT166 [nTPM]":"20.1","Cell RNA - GAMG [nTPM]":"16.2","Cell RNA - HaCaT [nTPM]":"30.5","Cell RNA - HAP1 [nTPM]":"21.5","Cell RNA - HBEC3-KT [nTPM]":"24.4","Cell RNA - HBF TERT88 [nTPM]":"14.7","Cell RNA - HDLM-2 [nTPM]":"11.7","Cell RNA - HEK 293 [nTPM]":"25.3","Cell RNA - HEL [nTPM]":"11.4","Cell RNA - HeLa [nTPM]":"12.0","Cell RNA - Hep G2 [nTPM]":"43.4","Cell RNA - HHSteC [nTPM]":"16.2","Cell RNA - HL-60 [nTPM]":"5.5","Cell RNA - HMC-1 [nTPM]":"10.3","Cell RNA - HSkMC [nTPM]":"15.2","Cell RNA - hTCEpi [nTPM]":"20.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.8","Cell RNA - hTERT-HME1 [nTPM]":"14.1","Cell RNA - hTERT-RPE1 [nTPM]":"27.9","Cell RNA - HUVEC TERT2 [nTPM]":"25.6","Cell RNA - JURKAT [nTPM]":"22.0","Cell RNA - K-562 [nTPM]":"23.1","Cell RNA - Karpas-707 [nTPM]":"5.5","Cell RNA - LHCN-M2 [nTPM]":"21.7","Cell RNA - MCF7 [nTPM]":"21.0","Cell RNA - MOLT-4 [nTPM]":"14.4","Cell RNA - NB-4 [nTPM]":"22.5","Cell RNA - NTERA-2 [nTPM]":"21.9","Cell RNA - OE19 [nTPM]":"23.8","Cell RNA - PC-3 [nTPM]":"21.4","Cell RNA - REH [nTPM]":"31.8","Cell RNA - RH-30 [nTPM]":"26.2","Cell RNA - RPMI-8226 [nTPM]":"10.8","Cell RNA - RPTEC TERT1 [nTPM]":"15.9","Cell RNA - RT4 [nTPM]":"17.3","Cell RNA - SCLC-21H [nTPM]":"16.4","Cell RNA - SH-SY5Y [nTPM]":"10.5","Cell RNA - SiHa [nTPM]":"44.9","Cell RNA - SK-BR-3 [nTPM]":"8.3","Cell RNA - SK-MEL-30 [nTPM]":"9.5","Cell RNA - SuSa [nTPM]":"15.2","Cell RNA - T-47d [nTPM]":"22.6","Cell RNA - THP-1 [nTPM]":"17.0","Cell RNA - TIME [nTPM]":"33.7","Cell RNA - U-138 MG [nTPM]":"13.9","Cell RNA - U-2 OS [nTPM]":"17.2","Cell RNA - U-2197 [nTPM]":"12.0","Cell RNA - U-251 MG [nTPM]":"12.2","Cell RNA - U-266\/70 [nTPM]":"13.7","Cell RNA - U-266\/84 [nTPM]":"19.8","Cell RNA - U-698 [nTPM]":"12.8","Cell RNA - U-87 MG [nTPM]":"17.7","Cell RNA - U-937 [nTPM]":"19.8","Cell RNA - WM-115 [nTPM]":"17.7","Blood RNA - basophil [nTPM]":"4.5","Blood RNA - classical monocyte [nTPM]":"2.5","Blood RNA - eosinophil [nTPM]":"3.9","Blood RNA - gdT-cell [nTPM]":"2.7","Blood RNA - intermediate monocyte [nTPM]":"2.4","Blood RNA - MAIT T-cell [nTPM]":"2.6","Blood RNA - memory B-cell [nTPM]":"1.6","Blood RNA - memory CD4 T-cell [nTPM]":"1.7","Blood RNA - memory CD8 T-cell [nTPM]":"1.3","Blood RNA - myeloid DC [nTPM]":"2.8","Blood RNA - naive B-cell [nTPM]":"3.4","Blood RNA - naive CD4 T-cell [nTPM]":"3.1","Blood RNA - naive CD8 T-cell [nTPM]":"2.0","Blood RNA - neutrophil [nTPM]":"2.9","Blood RNA - NK-cell [nTPM]":"3.7","Blood RNA - non-classical monocyte [nTPM]":"1.7","Blood RNA - plasmacytoid DC [nTPM]":"2.3","Blood RNA - T-reg [nTPM]":"1.8","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"19.3","Brain RNA - basal ganglia [nTPM]":"18.8","Brain RNA - cerebellum [nTPM]":"21.3","Brain RNA - cerebral cortex [nTPM]":"28.6","Brain RNA - hippocampal formation [nTPM]":"19.4","Brain RNA - hypothalamus [nTPM]":"18.3","Brain RNA - medulla oblongata [nTPM]":"19.7","Brain RNA - midbrain [nTPM]":"18.6","Brain RNA - pons [nTPM]":"20.3","Brain RNA - spinal cord [nTPM]":"16.9","Brain RNA - thalamus [nTPM]":"18.7","Brain RNA - white matter [nTPM]":"20.0","Single Cell Type RNA - Adipocytes [nTPM]":"53.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"49.4","Single Cell Type RNA - Astrocytes [nTPM]":"39.2","Single Cell Type RNA - B-cells [nTPM]":"45.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"44.9","Single Cell Type RNA - Bipolar cells [nTPM]":"57.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"31.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"37.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"45.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"41.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"35.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"95.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"39.9","Single Cell Type RNA - dendritic cells [nTPM]":"47.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"42.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"40.0","Single Cell Type RNA - Early spermatids [nTPM]":"66.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"50.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"41.7","Single Cell Type RNA - Endothelial cells [nTPM]":"49.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"37.2","Single Cell Type RNA - Erythroid cells [nTPM]":"27.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"58.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"28.8","Single Cell Type RNA - Fibroblasts [nTPM]":"35.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"67.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"54.1","Single Cell Type RNA - granulocytes [nTPM]":"21.5","Single Cell Type RNA - Granulosa cells [nTPM]":"95.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"51.0","Single Cell Type RNA - Hepatocytes [nTPM]":"38.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"32.2","Single Cell Type RNA - Horizontal cells [nTPM]":"40.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"53.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"43.8","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"34.8","Single Cell Type RNA - Langerhans cells [nTPM]":"21.8","Single Cell Type RNA - Late spermatids [nTPM]":"22.1","Single Cell Type RNA - Leydig cells [nTPM]":"42.9","Single Cell Type RNA - Macrophages [nTPM]":"35.2","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"35.6","Single Cell Type RNA - monocytes [nTPM]":"42.6","Single Cell Type RNA - Muller glia cells [nTPM]":"30.5","Single Cell Type RNA - NK-cells [nTPM]":"51.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"87.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"46.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"39.5","Single Cell Type RNA - Paneth cells [nTPM]":"39.5","Single Cell Type RNA - Peritubular cells [nTPM]":"33.4","Single Cell Type RNA - Plasma cells [nTPM]":"43.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"29.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"68.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"37.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"73.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"36.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"36.2","Single Cell Type RNA - Spermatocytes [nTPM]":"57.5","Single Cell Type RNA - Spermatogonia [nTPM]":"36.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"36.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"25.9","Single Cell Type RNA - T-cells [nTPM]":"45.5","Single Cell Type RNA - Theca cells [nTPM]":"68.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"51.0","Single Cell Type RNA - Urothelial cells [nTPM]":"28.7"},{"Gene":"SPHK2","Gene synonym":[],"Ensembl":"ENSG00000063176","Gene description":"Sphingosine kinase 2","Uniprot":["Q9NRA0"],"Chromosome":"19","Position":"48619291-48630717","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"68.5","Cone photoreceptor cells":"77.2","Rod photoreceptor cells":"79.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"NB-4":"64.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049062"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA049062":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.19e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.30e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.59e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.97e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.4","Tissue RNA - adrenal gland [nTPM]":"10.5","Tissue RNA - amygdala [nTPM]":"18.9","Tissue RNA - appendix [nTPM]":"6.8","Tissue RNA - basal ganglia [nTPM]":"20.6","Tissue RNA - bone marrow [nTPM]":"3.4","Tissue RNA - breast [nTPM]":"9.6","Tissue RNA - cerebellum [nTPM]":"23.5","Tissue RNA - cerebral cortex [nTPM]":"29.3","Tissue RNA - cervix [nTPM]":"9.4","Tissue RNA - choroid plexus [nTPM]":"9.1","Tissue RNA - colon [nTPM]":"16.5","Tissue RNA - duodenum [nTPM]":"22.1","Tissue RNA - endometrium 1 [nTPM]":"12.0","Tissue RNA - epididymis [nTPM]":"2.1","Tissue RNA - esophagus [nTPM]":"9.2","Tissue RNA - fallopian tube [nTPM]":"11.6","Tissue RNA - gallbladder [nTPM]":"3.1","Tissue RNA - heart muscle [nTPM]":"7.3","Tissue RNA - hippocampal formation [nTPM]":"25.9","Tissue RNA - hypothalamus [nTPM]":"19.4","Tissue RNA - kidney [nTPM]":"23.1","Tissue RNA - liver [nTPM]":"31.8","Tissue RNA - lung [nTPM]":"8.5","Tissue RNA - lymph node [nTPM]":"5.9","Tissue RNA - medulla oblongata [nTPM]":"36.0","Tissue RNA - midbrain [nTPM]":"30.5","Tissue RNA - ovary [nTPM]":"15.5","Tissue RNA - pancreas [nTPM]":"8.9","Tissue RNA - parathyroid gland [nTPM]":"7.4","Tissue RNA - pituitary gland [nTPM]":"16.5","Tissue RNA - placenta [nTPM]":"2.2","Tissue RNA - pons [nTPM]":"37.2","Tissue RNA - prostate [nTPM]":"13.3","Tissue RNA - rectum [nTPM]":"3.6","Tissue RNA - retina [nTPM]":"3.2","Tissue RNA - salivary gland [nTPM]":"7.6","Tissue RNA - seminal vesicle [nTPM]":"4.4","Tissue RNA - skeletal muscle [nTPM]":"7.8","Tissue RNA - skin 1 [nTPM]":"4.8","Tissue RNA - small intestine [nTPM]":"18.9","Tissue RNA - smooth muscle [nTPM]":"2.6","Tissue RNA - spinal cord [nTPM]":"21.2","Tissue RNA - spleen [nTPM]":"11.4","Tissue RNA - stomach 1 [nTPM]":"14.8","Tissue RNA - testis [nTPM]":"24.1","Tissue RNA - thalamus [nTPM]":"30.6","Tissue RNA - thymus [nTPM]":"5.3","Tissue RNA - thyroid gland [nTPM]":"16.0","Tissue RNA - tongue [nTPM]":"3.1","Tissue RNA - tonsil [nTPM]":"3.1","Tissue RNA - urinary bladder [nTPM]":"10.7","Tissue RNA - vagina [nTPM]":"7.3","Tissue RNA - white matter [nTPM]":"26.1","Cell RNA - A-431 [nTPM]":"8.4","Cell RNA - A549 [nTPM]":"22.3","Cell RNA - AF22 [nTPM]":"8.2","Cell RNA - AN3-CA [nTPM]":"15.3","Cell RNA - ASC diff [nTPM]":"8.5","Cell RNA - ASC TERT1 [nTPM]":"3.6","Cell RNA - BEWO [nTPM]":"16.3","Cell RNA - BJ [nTPM]":"8.5","Cell RNA - BJ hTERT+ [nTPM]":"6.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.1","Cell RNA - CACO-2 [nTPM]":"39.8","Cell RNA - CAPAN-2 [nTPM]":"10.4","Cell RNA - Daudi [nTPM]":"15.0","Cell RNA - EFO-21 [nTPM]":"5.9","Cell RNA - fHDF\/TERT166 [nTPM]":"5.3","Cell RNA - GAMG [nTPM]":"5.6","Cell RNA - HaCaT [nTPM]":"6.4","Cell RNA - HAP1 [nTPM]":"7.5","Cell RNA - HBEC3-KT [nTPM]":"6.9","Cell RNA - HBF TERT88 [nTPM]":"1.3","Cell RNA - HDLM-2 [nTPM]":"17.5","Cell RNA - HEK 293 [nTPM]":"19.4","Cell RNA - HEL [nTPM]":"16.9","Cell RNA - HeLa [nTPM]":"11.5","Cell RNA - Hep G2 [nTPM]":"13.7","Cell RNA - HHSteC [nTPM]":"13.5","Cell RNA - HL-60 [nTPM]":"11.1","Cell RNA - HMC-1 [nTPM]":"17.3","Cell RNA - HSkMC [nTPM]":"6.5","Cell RNA - hTCEpi [nTPM]":"3.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.5","Cell RNA - hTERT-HME1 [nTPM]":"4.4","Cell RNA - hTERT-RPE1 [nTPM]":"4.4","Cell RNA - HUVEC TERT2 [nTPM]":"5.2","Cell RNA - JURKAT [nTPM]":"20.9","Cell RNA - K-562 [nTPM]":"11.7","Cell RNA - Karpas-707 [nTPM]":"12.5","Cell RNA - LHCN-M2 [nTPM]":"4.7","Cell RNA - MCF7 [nTPM]":"8.3","Cell RNA - MOLT-4 [nTPM]":"27.2","Cell RNA - NB-4 [nTPM]":"64.7","Cell RNA - NTERA-2 [nTPM]":"11.2","Cell RNA - OE19 [nTPM]":"6.0","Cell RNA - PC-3 [nTPM]":"10.7","Cell RNA - REH [nTPM]":"23.3","Cell RNA - RH-30 [nTPM]":"6.5","Cell RNA - RPMI-8226 [nTPM]":"10.0","Cell RNA - RPTEC TERT1 [nTPM]":"4.3","Cell RNA - RT4 [nTPM]":"5.3","Cell RNA - SCLC-21H [nTPM]":"29.3","Cell RNA - SH-SY5Y [nTPM]":"23.1","Cell RNA - SiHa [nTPM]":"8.3","Cell RNA - SK-BR-3 [nTPM]":"12.7","Cell RNA - SK-MEL-30 [nTPM]":"8.3","Cell RNA - SuSa [nTPM]":"4.5","Cell RNA - T-47d [nTPM]":"7.1","Cell RNA - THP-1 [nTPM]":"6.9","Cell RNA - TIME [nTPM]":"8.5","Cell RNA - U-138 MG [nTPM]":"13.6","Cell RNA - U-2 OS [nTPM]":"7.7","Cell RNA - U-2197 [nTPM]":"10.9","Cell RNA - U-251 MG [nTPM]":"17.1","Cell RNA - U-266\/70 [nTPM]":"24.5","Cell RNA - U-266\/84 [nTPM]":"31.0","Cell RNA - U-698 [nTPM]":"16.4","Cell RNA - U-87 MG [nTPM]":"7.9","Cell RNA - U-937 [nTPM]":"12.2","Cell RNA - WM-115 [nTPM]":"12.6","Blood RNA - basophil [nTPM]":"11.7","Blood RNA - classical monocyte [nTPM]":"6.2","Blood RNA - eosinophil [nTPM]":"2.9","Blood RNA - gdT-cell [nTPM]":"4.3","Blood RNA - intermediate monocyte [nTPM]":"7.1","Blood RNA - MAIT T-cell [nTPM]":"4.0","Blood RNA - memory B-cell [nTPM]":"5.0","Blood RNA - memory CD4 T-cell [nTPM]":"3.4","Blood RNA - memory CD8 T-cell [nTPM]":"4.2","Blood RNA - myeloid DC [nTPM]":"5.5","Blood RNA - naive B-cell [nTPM]":"8.6","Blood RNA - naive CD4 T-cell [nTPM]":"4.8","Blood RNA - naive CD8 T-cell [nTPM]":"4.8","Blood RNA - neutrophil [nTPM]":"2.4","Blood RNA - NK-cell [nTPM]":"5.6","Blood RNA - non-classical monocyte [nTPM]":"6.2","Blood RNA - plasmacytoid DC [nTPM]":"5.4","Blood RNA - T-reg [nTPM]":"3.7","Blood RNA - total PBMC [nTPM]":"3.5","Brain RNA - amygdala [nTPM]":"18.9","Brain RNA - basal ganglia [nTPM]":"20.6","Brain RNA - cerebellum [nTPM]":"23.5","Brain RNA - cerebral cortex [nTPM]":"29.3","Brain RNA - hippocampal formation [nTPM]":"25.9","Brain RNA - hypothalamus [nTPM]":"19.4","Brain RNA - medulla oblongata [nTPM]":"36.0","Brain RNA - midbrain [nTPM]":"30.5","Brain RNA - pons [nTPM]":"37.2","Brain RNA - spinal cord [nTPM]":"21.2","Brain RNA - thalamus [nTPM]":"30.6","Brain RNA - white matter [nTPM]":"26.1","Single Cell Type RNA - Adipocytes [nTPM]":"3.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.7","Single Cell Type RNA - Astrocytes [nTPM]":"8.5","Single Cell Type RNA - B-cells [nTPM]":"13.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"68.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"6.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"77.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.8","Single Cell Type RNA - dendritic cells [nTPM]":"13.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"20.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.2","Single Cell Type RNA - Early spermatids [nTPM]":"11.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.1","Single Cell Type RNA - Endothelial cells [nTPM]":"6.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.2","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.3","Single Cell Type RNA - Fibroblasts [nTPM]":"5.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.9","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"14.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"19.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.3","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.3","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"12.3","Single Cell Type RNA - Langerhans cells [nTPM]":"7.3","Single Cell Type RNA - Late spermatids [nTPM]":"18.4","Single Cell Type RNA - Leydig cells [nTPM]":"16.4","Single Cell Type RNA - Macrophages [nTPM]":"6.5","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"11.4","Single Cell Type RNA - Muller glia cells [nTPM]":"20.8","Single Cell Type RNA - NK-cells [nTPM]":"33.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.8","Single Cell Type RNA - Paneth cells [nTPM]":"16.7","Single Cell Type RNA - Peritubular cells [nTPM]":"12.8","Single Cell Type RNA - Plasma cells [nTPM]":"7.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"44.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"79.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.4","Single Cell Type RNA - Spermatocytes [nTPM]":"18.1","Single Cell Type RNA - Spermatogonia [nTPM]":"6.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.5","Single Cell Type RNA - T-cells [nTPM]":"12.3","Single Cell Type RNA - Theca cells [nTPM]":"8.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.3","Single Cell Type RNA - Urothelial cells [nTPM]":"4.3"},{"Gene":"SPNS2","Gene synonym":["SLC62A2"],"Ensembl":"ENSG00000183018","Gene description":"Sphingolipid transporter 2","Uniprot":["Q8IVW8"],"Chromosome":"17","Position":"4498881-4539035","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"51.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"32.7","Endothelial cells":"34.5","Microglial cells":"37.5","Oligodendrocytes":"97.8","Urothelial cells":"39.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"31.0","RPTEC TERT1":"161.7","SK-BR-3":"76.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA068717"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA068717":"AB_2686021"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"},"Tissue RNA - adipose tissue [nTPM]":"17.3","Tissue RNA - adrenal gland [nTPM]":"2.6","Tissue RNA - amygdala [nTPM]":"13.1","Tissue RNA - appendix [nTPM]":"5.2","Tissue RNA - basal ganglia [nTPM]":"14.0","Tissue RNA - bone marrow [nTPM]":"7.9","Tissue RNA - breast [nTPM]":"14.7","Tissue RNA - cerebellum [nTPM]":"13.1","Tissue RNA - cerebral cortex [nTPM]":"18.2","Tissue RNA - cervix [nTPM]":"14.6","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"6.5","Tissue RNA - duodenum [nTPM]":"12.2","Tissue RNA - endometrium 1 [nTPM]":"8.6","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"51.0","Tissue RNA - fallopian tube [nTPM]":"7.8","Tissue RNA - gallbladder [nTPM]":"12.1","Tissue RNA - heart muscle [nTPM]":"10.7","Tissue RNA - hippocampal formation [nTPM]":"14.1","Tissue RNA - hypothalamus [nTPM]":"12.1","Tissue RNA - kidney [nTPM]":"28.6","Tissue RNA - liver [nTPM]":"3.8","Tissue RNA - lung [nTPM]":"28.3","Tissue RNA - lymph node [nTPM]":"4.9","Tissue RNA - medulla oblongata [nTPM]":"26.4","Tissue RNA - midbrain [nTPM]":"16.2","Tissue RNA - ovary [nTPM]":"1.8","Tissue RNA - pancreas [nTPM]":"10.0","Tissue RNA - parathyroid gland [nTPM]":"1.1","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"7.9","Tissue RNA - pons [nTPM]":"28.9","Tissue RNA - prostate [nTPM]":"5.3","Tissue RNA - rectum [nTPM]":"2.1","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"16.5","Tissue RNA - seminal vesicle [nTPM]":"2.0","Tissue RNA - skeletal muscle [nTPM]":"4.4","Tissue RNA - skin 1 [nTPM]":"24.8","Tissue RNA - small intestine [nTPM]":"10.8","Tissue RNA - smooth muscle [nTPM]":"4.8","Tissue RNA - spinal cord [nTPM]":"13.9","Tissue RNA - spleen [nTPM]":"11.4","Tissue RNA - stomach 1 [nTPM]":"21.0","Tissue RNA - testis [nTPM]":"1.3","Tissue RNA - thalamus [nTPM]":"15.5","Tissue RNA - thymus [nTPM]":"1.7","Tissue RNA - thyroid gland [nTPM]":"8.5","Tissue RNA - tongue [nTPM]":"3.9","Tissue RNA - tonsil [nTPM]":"13.3","Tissue RNA - urinary bladder [nTPM]":"6.6","Tissue RNA - vagina [nTPM]":"22.6","Tissue RNA - white matter [nTPM]":"25.1","Cell RNA - A-431 [nTPM]":"9.7","Cell RNA - A549 [nTPM]":"1.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"31.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"8.1","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"11.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.7","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"3.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"4.2","Cell RNA - JURKAT [nTPM]":"4.7","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"3.8","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"17.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"17.6","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.8","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"161.7","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"5.4","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"76.7","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"5.1","Cell RNA - T-47d [nTPM]":"2.7","Cell RNA - THP-1 [nTPM]":"7.5","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"8.2","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"13.1","Brain RNA - basal ganglia [nTPM]":"14.0","Brain RNA - cerebellum [nTPM]":"13.1","Brain RNA - cerebral cortex [nTPM]":"18.2","Brain RNA - hippocampal formation [nTPM]":"14.1","Brain RNA - hypothalamus [nTPM]":"12.1","Brain RNA - medulla oblongata [nTPM]":"26.4","Brain RNA - midbrain [nTPM]":"16.2","Brain RNA - pons [nTPM]":"28.9","Brain RNA - spinal cord [nTPM]":"13.9","Brain RNA - thalamus [nTPM]":"15.5","Brain RNA - white matter [nTPM]":"25.1","Single Cell Type RNA - Adipocytes [nTPM]":"32.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.6","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"16.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"16.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.0","Single Cell Type RNA - Endothelial cells [nTPM]":"34.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"3.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"30.5","Single Cell Type RNA - Fibroblasts [nTPM]":"1.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"26.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.5","Single Cell Type RNA - Hepatocytes [nTPM]":"6.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.1","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"26.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.7","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"1.9","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"37.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"97.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"1.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"24.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - T-cells [nTPM]":"1.6","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.1","Single Cell Type RNA - Urothelial cells [nTPM]":"39.8"},{"Gene":"SPR","Gene synonym":["SDR38C1"],"Ensembl":"ENSG00000116096","Gene description":"Sepiapterin reductase","Uniprot":["P35270"],"Chromosome":"2","Position":"72887382-72892158","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Dystonia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"85.3","Exocrine glandular cells":"81.1","Proximal tubular cells":"91.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"classical monocyte":"8.3","intermediate monocyte":"2.4","myeloid DC":"8.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"dendritic cells":"8.9","monocytes":"8.3"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039505"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"180000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 1: Pancreatic cells - Digestion","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA039505":"AB_10795466"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.72e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.50e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Tissue RNA - adipose tissue [nTPM]":"25.9","Tissue RNA - adrenal gland [nTPM]":"50.8","Tissue RNA - amygdala [nTPM]":"26.0","Tissue RNA - appendix [nTPM]":"7.6","Tissue RNA - basal ganglia [nTPM]":"27.2","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"20.0","Tissue RNA - cerebellum [nTPM]":"27.2","Tissue RNA - cerebral cortex [nTPM]":"61.4","Tissue RNA - cervix [nTPM]":"14.5","Tissue RNA - choroid plexus [nTPM]":"39.6","Tissue RNA - colon [nTPM]":"36.4","Tissue RNA - duodenum [nTPM]":"23.4","Tissue RNA - endometrium 1 [nTPM]":"13.4","Tissue RNA - epididymis [nTPM]":"36.9","Tissue RNA - esophagus [nTPM]":"19.7","Tissue RNA - fallopian tube [nTPM]":"26.3","Tissue RNA - gallbladder [nTPM]":"11.9","Tissue RNA - heart muscle [nTPM]":"44.4","Tissue RNA - hippocampal formation [nTPM]":"26.8","Tissue RNA - hypothalamus [nTPM]":"30.0","Tissue RNA - kidney [nTPM]":"44.2","Tissue RNA - liver [nTPM]":"99.8","Tissue RNA - lung [nTPM]":"15.9","Tissue RNA - lymph node [nTPM]":"3.2","Tissue RNA - medulla oblongata [nTPM]":"27.9","Tissue RNA - midbrain [nTPM]":"31.5","Tissue RNA - ovary [nTPM]":"12.2","Tissue RNA - pancreas [nTPM]":"63.5","Tissue RNA - parathyroid gland [nTPM]":"38.4","Tissue RNA - pituitary gland [nTPM]":"10.9","Tissue RNA - placenta [nTPM]":"6.8","Tissue RNA - pons [nTPM]":"29.8","Tissue RNA - prostate [nTPM]":"26.2","Tissue RNA - rectum [nTPM]":"32.5","Tissue RNA - retina [nTPM]":"3.1","Tissue RNA - salivary gland [nTPM]":"31.2","Tissue RNA - seminal vesicle [nTPM]":"16.7","Tissue RNA - skeletal muscle [nTPM]":"43.9","Tissue RNA - skin 1 [nTPM]":"9.1","Tissue RNA - small intestine [nTPM]":"22.0","Tissue RNA - smooth muscle [nTPM]":"11.5","Tissue RNA - spinal cord [nTPM]":"27.9","Tissue RNA - spleen [nTPM]":"9.6","Tissue RNA - stomach 1 [nTPM]":"42.1","Tissue RNA - testis [nTPM]":"7.3","Tissue RNA - thalamus [nTPM]":"28.5","Tissue RNA - thymus [nTPM]":"2.4","Tissue RNA - thyroid gland [nTPM]":"20.5","Tissue RNA - tongue [nTPM]":"25.4","Tissue RNA - tonsil [nTPM]":"5.1","Tissue RNA - urinary bladder [nTPM]":"25.2","Tissue RNA - vagina [nTPM]":"13.7","Tissue RNA - white matter [nTPM]":"28.0","Cell RNA - A-431 [nTPM]":"47.5","Cell RNA - A549 [nTPM]":"130.9","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"20.0","Cell RNA - ASC diff [nTPM]":"51.2","Cell RNA - ASC TERT1 [nTPM]":"18.5","Cell RNA - BEWO [nTPM]":"31.8","Cell RNA - BJ [nTPM]":"21.4","Cell RNA - BJ hTERT+ [nTPM]":"31.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.0","Cell RNA - CACO-2 [nTPM]":"84.0","Cell RNA - CAPAN-2 [nTPM]":"48.0","Cell RNA - Daudi [nTPM]":"34.5","Cell RNA - EFO-21 [nTPM]":"25.4","Cell RNA - fHDF\/TERT166 [nTPM]":"26.1","Cell RNA - GAMG [nTPM]":"80.6","Cell RNA - HaCaT [nTPM]":"43.9","Cell RNA - HAP1 [nTPM]":"58.1","Cell RNA - HBEC3-KT [nTPM]":"35.1","Cell RNA - HBF TERT88 [nTPM]":"13.3","Cell RNA - HDLM-2 [nTPM]":"10.0","Cell RNA - HEK 293 [nTPM]":"43.7","Cell RNA - HEL [nTPM]":"51.7","Cell RNA - HeLa [nTPM]":"30.8","Cell RNA - Hep G2 [nTPM]":"87.4","Cell RNA - HHSteC [nTPM]":"19.1","Cell RNA - HL-60 [nTPM]":"8.2","Cell RNA - HMC-1 [nTPM]":"13.6","Cell RNA - HSkMC [nTPM]":"16.7","Cell RNA - hTCEpi [nTPM]":"38.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"17.6","Cell RNA - hTERT-HME1 [nTPM]":"19.7","Cell RNA - hTERT-RPE1 [nTPM]":"32.7","Cell RNA - HUVEC TERT2 [nTPM]":"42.6","Cell RNA - JURKAT [nTPM]":"25.4","Cell RNA - K-562 [nTPM]":"54.0","Cell RNA - Karpas-707 [nTPM]":"6.8","Cell RNA - LHCN-M2 [nTPM]":"21.4","Cell RNA - MCF7 [nTPM]":"100.5","Cell RNA - MOLT-4 [nTPM]":"3.3","Cell RNA - NB-4 [nTPM]":"31.1","Cell RNA - NTERA-2 [nTPM]":"10.9","Cell RNA - OE19 [nTPM]":"139.9","Cell RNA - PC-3 [nTPM]":"118.7","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"82.8","Cell RNA - RPMI-8226 [nTPM]":"20.3","Cell RNA - RPTEC TERT1 [nTPM]":"85.8","Cell RNA - RT4 [nTPM]":"73.4","Cell RNA - SCLC-21H [nTPM]":"8.0","Cell RNA - SH-SY5Y [nTPM]":"14.6","Cell RNA - SiHa [nTPM]":"39.6","Cell RNA - SK-BR-3 [nTPM]":"89.7","Cell RNA - SK-MEL-30 [nTPM]":"31.0","Cell RNA - SuSa [nTPM]":"16.9","Cell RNA - T-47d [nTPM]":"40.4","Cell RNA - THP-1 [nTPM]":"9.9","Cell RNA - TIME [nTPM]":"52.8","Cell RNA - U-138 MG [nTPM]":"17.4","Cell RNA - U-2 OS [nTPM]":"42.2","Cell RNA - U-2197 [nTPM]":"30.5","Cell RNA - U-251 MG [nTPM]":"38.7","Cell RNA - U-266\/70 [nTPM]":"7.2","Cell RNA - U-266\/84 [nTPM]":"16.9","Cell RNA - U-698 [nTPM]":"2.3","Cell RNA - U-87 MG [nTPM]":"25.0","Cell RNA - U-937 [nTPM]":"17.6","Cell RNA - WM-115 [nTPM]":"31.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"8.3","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"2.4","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"8.9","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"2.4","Brain RNA - amygdala [nTPM]":"26.0","Brain RNA - basal ganglia [nTPM]":"27.2","Brain RNA - cerebellum [nTPM]":"27.2","Brain RNA - cerebral cortex [nTPM]":"61.4","Brain RNA - hippocampal formation [nTPM]":"26.8","Brain RNA - hypothalamus [nTPM]":"30.0","Brain RNA - medulla oblongata [nTPM]":"27.9","Brain RNA - midbrain [nTPM]":"31.5","Brain RNA - pons [nTPM]":"29.8","Brain RNA - spinal cord [nTPM]":"27.9","Brain RNA - thalamus [nTPM]":"28.5","Brain RNA - white matter [nTPM]":"28.0","Single Cell Type RNA - Adipocytes [nTPM]":"13.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"20.5","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"46.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"10.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"42.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"85.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"56.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.2","Single Cell Type RNA - Endothelial cells [nTPM]":"16.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.4","Single Cell Type RNA - Erythroid cells [nTPM]":"6.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"81.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.6","Single Cell Type RNA - Fibroblasts [nTPM]":"13.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"26.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.7","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"8.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.2","Single Cell Type RNA - Hepatocytes [nTPM]":"62.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"42.1","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"39.6","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"6.0","Single Cell Type RNA - Langerhans cells [nTPM]":"7.4","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"9.3","Single Cell Type RNA - Macrophages [nTPM]":"9.7","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"20.8","Single Cell Type RNA - Muller glia cells [nTPM]":"13.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"43.3","Single Cell Type RNA - Paneth cells [nTPM]":"50.4","Single Cell Type RNA - Peritubular cells [nTPM]":"5.7","Single Cell Type RNA - Plasma cells [nTPM]":"1.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"33.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"71.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"91.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"10.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.4","Single Cell Type RNA - T-cells [nTPM]":"1.9","Single Cell Type RNA - Theca cells [nTPM]":"8.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"57.8","Single Cell Type RNA - Urothelial cells [nTPM]":"15.6"},{"Gene":"SPTLC1","Gene synonym":["hLCB1","HSAN1","HSN1","LCB1","SPTI"],"Ensembl":"ENSG00000090054","Gene description":"Serine palmitoyltransferase long chain base subunit 1","Uniprot":["O15269"],"Chromosome":"9","Position":"92000087-92115413","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"94.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010860","CAB018747","HPA063907"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB018747":"AB_2195864","HPA010860":"AB_1080086","HPA063907":"AB_2685148"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.36e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Tissue RNA - adipose tissue [nTPM]":"35.6","Tissue RNA - adrenal gland [nTPM]":"32.6","Tissue RNA - amygdala [nTPM]":"24.0","Tissue RNA - appendix [nTPM]":"27.3","Tissue RNA - basal ganglia [nTPM]":"27.0","Tissue RNA - bone marrow [nTPM]":"23.3","Tissue RNA - breast [nTPM]":"44.1","Tissue RNA - cerebellum [nTPM]":"26.0","Tissue RNA - cerebral cortex [nTPM]":"34.2","Tissue RNA - cervix [nTPM]":"43.1","Tissue RNA - choroid plexus [nTPM]":"28.6","Tissue RNA - colon [nTPM]":"42.3","Tissue RNA - duodenum [nTPM]":"34.7","Tissue RNA - endometrium 1 [nTPM]":"40.4","Tissue RNA - epididymis [nTPM]":"41.3","Tissue RNA - esophagus [nTPM]":"54.3","Tissue RNA - fallopian tube [nTPM]":"36.7","Tissue RNA - gallbladder [nTPM]":"34.1","Tissue RNA - heart muscle [nTPM]":"21.5","Tissue RNA - hippocampal formation [nTPM]":"24.3","Tissue RNA - hypothalamus [nTPM]":"26.6","Tissue RNA - kidney [nTPM]":"42.8","Tissue RNA - liver [nTPM]":"23.4","Tissue RNA - lung [nTPM]":"33.6","Tissue RNA - lymph node [nTPM]":"25.7","Tissue RNA - medulla oblongata [nTPM]":"27.8","Tissue RNA - midbrain [nTPM]":"27.5","Tissue RNA - ovary [nTPM]":"43.8","Tissue RNA - pancreas [nTPM]":"26.5","Tissue RNA - parathyroid gland [nTPM]":"48.0","Tissue RNA - pituitary gland [nTPM]":"17.3","Tissue RNA - placenta [nTPM]":"42.4","Tissue RNA - pons [nTPM]":"28.0","Tissue RNA - prostate [nTPM]":"32.9","Tissue RNA - rectum [nTPM]":"44.1","Tissue RNA - retina [nTPM]":"19.8","Tissue RNA - salivary gland [nTPM]":"31.3","Tissue RNA - seminal vesicle [nTPM]":"28.1","Tissue RNA - skeletal muscle [nTPM]":"14.2","Tissue RNA - skin 1 [nTPM]":"41.3","Tissue RNA - small intestine [nTPM]":"37.9","Tissue RNA - smooth muscle [nTPM]":"31.4","Tissue RNA - spinal cord [nTPM]":"27.9","Tissue RNA - spleen [nTPM]":"26.3","Tissue RNA - stomach 1 [nTPM]":"37.1","Tissue RNA - testis [nTPM]":"26.5","Tissue RNA - thalamus [nTPM]":"25.6","Tissue RNA - thymus [nTPM]":"25.9","Tissue RNA - thyroid gland [nTPM]":"53.0","Tissue RNA - tongue [nTPM]":"18.6","Tissue RNA - tonsil [nTPM]":"34.4","Tissue RNA - urinary bladder [nTPM]":"37.2","Tissue RNA - vagina [nTPM]":"34.7","Tissue RNA - white matter [nTPM]":"31.6","Cell RNA - A-431 [nTPM]":"73.0","Cell RNA - A549 [nTPM]":"48.8","Cell RNA - AF22 [nTPM]":"46.8","Cell RNA - AN3-CA [nTPM]":"41.6","Cell RNA - ASC diff [nTPM]":"120.0","Cell RNA - ASC TERT1 [nTPM]":"92.0","Cell RNA - BEWO [nTPM]":"78.4","Cell RNA - BJ [nTPM]":"74.7","Cell RNA - BJ hTERT+ [nTPM]":"94.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"65.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"66.3","Cell RNA - CACO-2 [nTPM]":"31.5","Cell RNA - CAPAN-2 [nTPM]":"150.7","Cell RNA - Daudi [nTPM]":"38.6","Cell RNA - EFO-21 [nTPM]":"45.1","Cell RNA - fHDF\/TERT166 [nTPM]":"93.9","Cell RNA - GAMG [nTPM]":"78.3","Cell RNA - HaCaT [nTPM]":"198.4","Cell RNA - HAP1 [nTPM]":"49.7","Cell RNA - HBEC3-KT [nTPM]":"68.1","Cell RNA - HBF TERT88 [nTPM]":"73.0","Cell RNA - HDLM-2 [nTPM]":"39.8","Cell RNA - HEK 293 [nTPM]":"36.1","Cell RNA - HEL [nTPM]":"36.7","Cell RNA - HeLa [nTPM]":"32.7","Cell RNA - Hep G2 [nTPM]":"51.7","Cell RNA - HHSteC [nTPM]":"80.5","Cell RNA - HL-60 [nTPM]":"65.5","Cell RNA - HMC-1 [nTPM]":"49.9","Cell RNA - HSkMC [nTPM]":"82.6","Cell RNA - hTCEpi [nTPM]":"92.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"68.0","Cell RNA - hTERT-HME1 [nTPM]":"74.8","Cell RNA - hTERT-RPE1 [nTPM]":"72.3","Cell RNA - HUVEC TERT2 [nTPM]":"62.5","Cell RNA - JURKAT [nTPM]":"43.5","Cell RNA - K-562 [nTPM]":"83.8","Cell RNA - Karpas-707 [nTPM]":"46.6","Cell RNA - LHCN-M2 [nTPM]":"91.1","Cell RNA - MCF7 [nTPM]":"69.6","Cell RNA - MOLT-4 [nTPM]":"34.7","Cell RNA - NB-4 [nTPM]":"47.6","Cell RNA - NTERA-2 [nTPM]":"67.5","Cell RNA - OE19 [nTPM]":"97.4","Cell RNA - PC-3 [nTPM]":"57.9","Cell RNA - REH [nTPM]":"39.4","Cell RNA - RH-30 [nTPM]":"58.7","Cell RNA - RPMI-8226 [nTPM]":"33.3","Cell RNA - RPTEC TERT1 [nTPM]":"84.1","Cell RNA - RT4 [nTPM]":"37.9","Cell RNA - SCLC-21H [nTPM]":"35.0","Cell RNA - SH-SY5Y [nTPM]":"37.2","Cell RNA - SiHa [nTPM]":"104.4","Cell RNA - SK-BR-3 [nTPM]":"81.1","Cell RNA - SK-MEL-30 [nTPM]":"61.3","Cell RNA - SuSa [nTPM]":"62.4","Cell RNA - T-47d [nTPM]":"39.2","Cell RNA - THP-1 [nTPM]":"54.2","Cell RNA - TIME [nTPM]":"72.3","Cell RNA - U-138 MG [nTPM]":"58.8","Cell RNA - U-2 OS [nTPM]":"48.0","Cell RNA - U-2197 [nTPM]":"73.9","Cell RNA - U-251 MG [nTPM]":"56.8","Cell RNA - U-266\/70 [nTPM]":"33.2","Cell RNA - U-266\/84 [nTPM]":"44.4","Cell RNA - U-698 [nTPM]":"23.9","Cell RNA - U-87 MG [nTPM]":"74.2","Cell RNA - U-937 [nTPM]":"39.3","Cell RNA - WM-115 [nTPM]":"79.4","Blood RNA - basophil [nTPM]":"32.4","Blood RNA - classical monocyte [nTPM]":"33.1","Blood RNA - eosinophil [nTPM]":"20.2","Blood RNA - gdT-cell [nTPM]":"16.7","Blood RNA - intermediate monocyte [nTPM]":"36.1","Blood RNA - MAIT T-cell [nTPM]":"17.0","Blood RNA - memory B-cell [nTPM]":"15.4","Blood RNA - memory CD4 T-cell [nTPM]":"18.0","Blood RNA - memory CD8 T-cell [nTPM]":"17.4","Blood RNA - myeloid DC [nTPM]":"30.6","Blood RNA - naive B-cell [nTPM]":"15.5","Blood RNA - naive CD4 T-cell [nTPM]":"21.4","Blood RNA - naive CD8 T-cell [nTPM]":"16.6","Blood RNA - neutrophil [nTPM]":"33.3","Blood RNA - NK-cell [nTPM]":"18.5","Blood RNA - non-classical monocyte [nTPM]":"34.2","Blood RNA - plasmacytoid DC [nTPM]":"18.4","Blood RNA - T-reg [nTPM]":"25.7","Blood RNA - total PBMC [nTPM]":"25.5","Brain RNA - amygdala [nTPM]":"24.0","Brain RNA - basal ganglia [nTPM]":"27.0","Brain RNA - cerebellum [nTPM]":"26.0","Brain RNA - cerebral cortex [nTPM]":"34.2","Brain RNA - hippocampal formation [nTPM]":"24.3","Brain RNA - hypothalamus [nTPM]":"26.6","Brain RNA - medulla oblongata [nTPM]":"27.8","Brain RNA - midbrain [nTPM]":"27.5","Brain RNA - pons [nTPM]":"28.0","Brain RNA - spinal cord [nTPM]":"27.9","Brain RNA - thalamus [nTPM]":"25.6","Brain RNA - white matter [nTPM]":"31.6","Single Cell Type RNA - Adipocytes [nTPM]":"40.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"38.3","Single Cell Type RNA - Astrocytes [nTPM]":"27.7","Single Cell Type RNA - B-cells [nTPM]":"22.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.2","Single Cell Type RNA - Bipolar cells [nTPM]":"6.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"33.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"25.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.7","Single Cell Type RNA - dendritic cells [nTPM]":"24.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"53.4","Single Cell Type RNA - Early spermatids [nTPM]":"94.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"34.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"42.5","Single Cell Type RNA - Endothelial cells [nTPM]":"23.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"7.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"35.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"56.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.6","Single Cell Type RNA - Fibroblasts [nTPM]":"32.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"47.4","Single Cell Type RNA - granulocytes [nTPM]":"24.6","Single Cell Type RNA - Granulosa cells [nTPM]":"26.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"4.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.0","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"32.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.2","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.7","Single Cell Type RNA - Langerhans cells [nTPM]":"10.3","Single Cell Type RNA - Late spermatids [nTPM]":"26.1","Single Cell Type RNA - Leydig cells [nTPM]":"6.2","Single Cell Type RNA - Macrophages [nTPM]":"24.6","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"22.0","Single Cell Type RNA - Muller glia cells [nTPM]":"13.7","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"36.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"52.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"60.8","Single Cell Type RNA - Paneth cells [nTPM]":"7.1","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"26.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"28.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.5","Single Cell Type RNA - Spermatocytes [nTPM]":"35.3","Single Cell Type RNA - Spermatogonia [nTPM]":"25.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"27.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"21.8","Single Cell Type RNA - T-cells [nTPM]":"21.9","Single Cell Type RNA - Theca cells [nTPM]":"33.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.9","Single Cell Type RNA - Urothelial cells [nTPM]":"14.5"},{"Gene":"SPTLC2","Gene synonym":["hLCB2a","KIAA0526","LCB2","LCB2A"],"Ensembl":"ENSG00000100596","Gene description":"Serine palmitoyltransferase long chain base subunit 2","Uniprot":["O15270"],"Chromosome":"14","Position":"77505997-77616637","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"164.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.62e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.69e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Tissue RNA - adipose tissue [nTPM]":"17.6","Tissue RNA - adrenal gland [nTPM]":"12.2","Tissue RNA - amygdala [nTPM]":"14.6","Tissue RNA - appendix [nTPM]":"12.6","Tissue RNA - basal ganglia [nTPM]":"26.7","Tissue RNA - bone marrow [nTPM]":"33.7","Tissue RNA - breast [nTPM]":"18.3","Tissue RNA - cerebellum [nTPM]":"24.0","Tissue RNA - cerebral cortex [nTPM]":"19.4","Tissue RNA - cervix [nTPM]":"15.2","Tissue RNA - choroid plexus [nTPM]":"9.9","Tissue RNA - colon [nTPM]":"18.5","Tissue RNA - duodenum [nTPM]":"14.5","Tissue RNA - endometrium 1 [nTPM]":"10.5","Tissue RNA - epididymis [nTPM]":"7.6","Tissue RNA - esophagus [nTPM]":"22.8","Tissue RNA - fallopian tube [nTPM]":"14.2","Tissue RNA - gallbladder [nTPM]":"11.8","Tissue RNA - heart muscle [nTPM]":"6.7","Tissue RNA - hippocampal formation [nTPM]":"15.3","Tissue RNA - hypothalamus [nTPM]":"18.1","Tissue RNA - kidney [nTPM]":"17.6","Tissue RNA - liver [nTPM]":"7.7","Tissue RNA - lung [nTPM]":"13.1","Tissue RNA - lymph node [nTPM]":"12.0","Tissue RNA - medulla oblongata [nTPM]":"30.7","Tissue RNA - midbrain [nTPM]":"21.5","Tissue RNA - ovary [nTPM]":"10.4","Tissue RNA - pancreas [nTPM]":"5.7","Tissue RNA - parathyroid gland [nTPM]":"10.7","Tissue RNA - pituitary gland [nTPM]":"6.2","Tissue RNA - placenta [nTPM]":"20.4","Tissue RNA - pons [nTPM]":"31.5","Tissue RNA - prostate [nTPM]":"8.4","Tissue RNA - rectum [nTPM]":"19.8","Tissue RNA - retina [nTPM]":"14.2","Tissue RNA - salivary gland [nTPM]":"13.7","Tissue RNA - seminal vesicle [nTPM]":"8.8","Tissue RNA - skeletal muscle [nTPM]":"3.9","Tissue RNA - skin 1 [nTPM]":"12.2","Tissue RNA - small intestine [nTPM]":"17.4","Tissue RNA - smooth muscle [nTPM]":"11.6","Tissue RNA - spinal cord [nTPM]":"25.3","Tissue RNA - spleen [nTPM]":"19.6","Tissue RNA - stomach 1 [nTPM]":"20.4","Tissue RNA - testis [nTPM]":"5.0","Tissue RNA - thalamus [nTPM]":"21.7","Tissue RNA - thymus [nTPM]":"10.3","Tissue RNA - thyroid gland [nTPM]":"10.9","Tissue RNA - tongue [nTPM]":"6.1","Tissue RNA - tonsil [nTPM]":"13.3","Tissue RNA - urinary bladder [nTPM]":"15.0","Tissue RNA - vagina [nTPM]":"10.8","Tissue RNA - white matter [nTPM]":"52.7","Cell RNA - A-431 [nTPM]":"28.9","Cell RNA - A549 [nTPM]":"18.5","Cell RNA - AF22 [nTPM]":"14.1","Cell RNA - AN3-CA [nTPM]":"15.5","Cell RNA - ASC diff [nTPM]":"14.3","Cell RNA - ASC TERT1 [nTPM]":"17.8","Cell RNA - BEWO [nTPM]":"23.7","Cell RNA - BJ [nTPM]":"41.7","Cell RNA - BJ hTERT+ [nTPM]":"30.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"28.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"29.3","Cell RNA - CACO-2 [nTPM]":"23.7","Cell RNA - CAPAN-2 [nTPM]":"62.3","Cell RNA - Daudi [nTPM]":"28.8","Cell RNA - EFO-21 [nTPM]":"10.4","Cell RNA - fHDF\/TERT166 [nTPM]":"42.7","Cell RNA - GAMG [nTPM]":"14.5","Cell RNA - HaCaT [nTPM]":"34.7","Cell RNA - HAP1 [nTPM]":"38.1","Cell RNA - HBEC3-KT [nTPM]":"23.7","Cell RNA - HBF TERT88 [nTPM]":"42.5","Cell RNA - HDLM-2 [nTPM]":"12.6","Cell RNA - HEK 293 [nTPM]":"11.0","Cell RNA - HEL [nTPM]":"82.5","Cell RNA - HeLa [nTPM]":"13.4","Cell RNA - Hep G2 [nTPM]":"14.3","Cell RNA - HHSteC [nTPM]":"12.1","Cell RNA - HL-60 [nTPM]":"8.4","Cell RNA - HMC-1 [nTPM]":"25.8","Cell RNA - HSkMC [nTPM]":"11.7","Cell RNA - hTCEpi [nTPM]":"11.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.4","Cell RNA - hTERT-HME1 [nTPM]":"20.4","Cell RNA - hTERT-RPE1 [nTPM]":"16.3","Cell RNA - HUVEC TERT2 [nTPM]":"40.6","Cell RNA - JURKAT [nTPM]":"19.4","Cell RNA - K-562 [nTPM]":"16.2","Cell RNA - Karpas-707 [nTPM]":"13.5","Cell RNA - LHCN-M2 [nTPM]":"16.2","Cell RNA - MCF7 [nTPM]":"24.9","Cell RNA - MOLT-4 [nTPM]":"22.2","Cell RNA - NB-4 [nTPM]":"28.7","Cell RNA - NTERA-2 [nTPM]":"9.2","Cell RNA - OE19 [nTPM]":"45.4","Cell RNA - PC-3 [nTPM]":"16.8","Cell RNA - REH [nTPM]":"23.5","Cell RNA - RH-30 [nTPM]":"14.3","Cell RNA - RPMI-8226 [nTPM]":"10.0","Cell RNA - RPTEC TERT1 [nTPM]":"32.9","Cell RNA - RT4 [nTPM]":"63.4","Cell RNA - SCLC-21H [nTPM]":"13.6","Cell RNA - SH-SY5Y [nTPM]":"17.1","Cell RNA - SiHa [nTPM]":"15.0","Cell RNA - SK-BR-3 [nTPM]":"50.3","Cell RNA - SK-MEL-30 [nTPM]":"15.8","Cell RNA - SuSa [nTPM]":"24.7","Cell RNA - T-47d [nTPM]":"61.8","Cell RNA - THP-1 [nTPM]":"15.3","Cell RNA - TIME [nTPM]":"25.9","Cell RNA - U-138 MG [nTPM]":"25.7","Cell RNA - U-2 OS [nTPM]":"18.2","Cell RNA - U-2197 [nTPM]":"9.6","Cell RNA - U-251 MG [nTPM]":"9.7","Cell RNA - U-266\/70 [nTPM]":"7.6","Cell RNA - U-266\/84 [nTPM]":"13.4","Cell RNA - U-698 [nTPM]":"19.1","Cell RNA - U-87 MG [nTPM]":"17.3","Cell RNA - U-937 [nTPM]":"29.4","Cell RNA - WM-115 [nTPM]":"14.8","Blood RNA - basophil [nTPM]":"18.3","Blood RNA - classical monocyte [nTPM]":"31.3","Blood RNA - eosinophil [nTPM]":"27.1","Blood RNA - gdT-cell [nTPM]":"6.1","Blood RNA - intermediate monocyte [nTPM]":"24.2","Blood RNA - MAIT T-cell [nTPM]":"5.7","Blood RNA - memory B-cell [nTPM]":"6.7","Blood RNA - memory CD4 T-cell [nTPM]":"5.1","Blood RNA - memory CD8 T-cell [nTPM]":"6.8","Blood RNA - myeloid DC [nTPM]":"31.2","Blood RNA - naive B-cell [nTPM]":"7.9","Blood RNA - naive CD4 T-cell [nTPM]":"3.5","Blood RNA - naive CD8 T-cell [nTPM]":"5.8","Blood RNA - neutrophil [nTPM]":"19.1","Blood RNA - NK-cell [nTPM]":"17.7","Blood RNA - non-classical monocyte [nTPM]":"31.8","Blood RNA - plasmacytoid DC [nTPM]":"11.1","Blood RNA - T-reg [nTPM]":"6.0","Blood RNA - total PBMC [nTPM]":"13.4","Brain RNA - amygdala [nTPM]":"14.6","Brain RNA - basal ganglia [nTPM]":"26.7","Brain RNA - cerebellum [nTPM]":"24.0","Brain RNA - cerebral cortex [nTPM]":"19.4","Brain RNA - hippocampal formation [nTPM]":"15.3","Brain RNA - hypothalamus [nTPM]":"18.1","Brain RNA - medulla oblongata [nTPM]":"30.7","Brain RNA - midbrain [nTPM]":"21.5","Brain RNA - pons [nTPM]":"31.5","Brain RNA - spinal cord [nTPM]":"25.3","Brain RNA - thalamus [nTPM]":"21.7","Brain RNA - white matter [nTPM]":"52.7","Single Cell Type RNA - Adipocytes [nTPM]":"125.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.3","Single Cell Type RNA - Astrocytes [nTPM]":"24.8","Single Cell Type RNA - B-cells [nTPM]":"27.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"32.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"28.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"27.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Bipolar cells [nTPM]":"15.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"24.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"30.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"47.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.9","Single Cell Type RNA - dendritic cells [nTPM]":"28.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"37.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"24.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"44.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"36.0","Single Cell Type RNA - Endothelial cells [nTPM]":"53.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.2","Single Cell Type RNA - Erythroid cells [nTPM]":"51.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"31.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.3","Single Cell Type RNA - Fibroblasts [nTPM]":"18.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"43.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"36.0","Single Cell Type RNA - granulocytes [nTPM]":"51.3","Single Cell Type RNA - Granulosa cells [nTPM]":"37.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"68.2","Single Cell Type RNA - Hepatocytes [nTPM]":"7.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.1","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"29.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"39.3","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"75.9","Single Cell Type RNA - Langerhans cells [nTPM]":"19.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.7","Single Cell Type RNA - Leydig cells [nTPM]":"14.6","Single Cell Type RNA - Macrophages [nTPM]":"66.2","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"83.4","Single Cell Type RNA - monocytes [nTPM]":"51.3","Single Cell Type RNA - Muller glia cells [nTPM]":"8.8","Single Cell Type RNA - NK-cells [nTPM]":"32.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"59.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"164.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"35.0","Single Cell Type RNA - Paneth cells [nTPM]":"30.4","Single Cell Type RNA - Peritubular cells [nTPM]":"15.8","Single Cell Type RNA - Plasma cells [nTPM]":"11.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"27.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"28.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"20.0","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"25.5","Single Cell Type RNA - Spermatocytes [nTPM]":"7.3","Single Cell Type RNA - Spermatogonia [nTPM]":"19.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"37.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"29.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.6","Single Cell Type RNA - T-cells [nTPM]":"23.3","Single Cell Type RNA - Theca cells [nTPM]":"14.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"33.0","Single Cell Type RNA - Urothelial cells [nTPM]":"60.0"},{"Gene":"SRD5A3","Gene synonym":["FLJ13352","SRD5A2L","SRD5A2L1"],"Ensembl":"ENSG00000128039","Gene description":"Steroid 5 alpha-reductase 3","Uniprot":["Q9H8P0"],"Chromosome":"4","Position":"55346213-55373100","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Cataract","Congenital disorder of glycosylation","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"245.5","Club cells":"245.2","Pancreatic endocrine cells":"155.5","Respiratory ciliated cells":"195.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SK-BR-3":"79.6"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027006"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA027006":"AB_1857469"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.39e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.80e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.85e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.52e-2"},"Tissue RNA - adipose tissue [nTPM]":"12.5","Tissue RNA - adrenal gland [nTPM]":"12.0","Tissue RNA - amygdala [nTPM]":"10.4","Tissue RNA - appendix [nTPM]":"2.5","Tissue RNA - basal ganglia [nTPM]":"11.5","Tissue RNA - bone marrow [nTPM]":"3.7","Tissue RNA - breast [nTPM]":"12.2","Tissue RNA - cerebellum [nTPM]":"11.0","Tissue RNA - cerebral cortex [nTPM]":"12.4","Tissue RNA - cervix [nTPM]":"12.9","Tissue RNA - choroid plexus [nTPM]":"9.2","Tissue RNA - colon [nTPM]":"7.3","Tissue RNA - duodenum [nTPM]":"3.8","Tissue RNA - endometrium 1 [nTPM]":"6.8","Tissue RNA - epididymis [nTPM]":"4.2","Tissue RNA - esophagus [nTPM]":"26.1","Tissue RNA - fallopian tube [nTPM]":"5.6","Tissue RNA - gallbladder [nTPM]":"10.3","Tissue RNA - heart muscle [nTPM]":"9.3","Tissue RNA - hippocampal formation [nTPM]":"10.7","Tissue RNA - hypothalamus [nTPM]":"10.1","Tissue RNA - kidney [nTPM]":"9.6","Tissue RNA - liver [nTPM]":"14.5","Tissue RNA - lung [nTPM]":"10.5","Tissue RNA - lymph node [nTPM]":"2.5","Tissue RNA - medulla oblongata [nTPM]":"11.0","Tissue RNA - midbrain [nTPM]":"11.2","Tissue RNA - ovary [nTPM]":"3.1","Tissue RNA - pancreas [nTPM]":"20.2","Tissue RNA - parathyroid gland [nTPM]":"7.0","Tissue RNA - pituitary gland [nTPM]":"5.9","Tissue RNA - placenta [nTPM]":"4.0","Tissue RNA - pons [nTPM]":"10.8","Tissue RNA - prostate [nTPM]":"7.4","Tissue RNA - rectum [nTPM]":"4.1","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"16.4","Tissue RNA - seminal vesicle [nTPM]":"2.9","Tissue RNA - skeletal muscle [nTPM]":"6.3","Tissue RNA - skin 1 [nTPM]":"15.4","Tissue RNA - small intestine [nTPM]":"7.0","Tissue RNA - smooth muscle [nTPM]":"2.6","Tissue RNA - spinal cord [nTPM]":"10.9","Tissue RNA - spleen [nTPM]":"6.8","Tissue RNA - stomach 1 [nTPM]":"9.7","Tissue RNA - testis [nTPM]":"3.3","Tissue RNA - thalamus [nTPM]":"10.9","Tissue RNA - thymus [nTPM]":"6.0","Tissue RNA - thyroid gland [nTPM]":"7.6","Tissue RNA - tongue [nTPM]":"5.4","Tissue RNA - tonsil [nTPM]":"6.0","Tissue RNA - urinary bladder [nTPM]":"10.0","Tissue RNA - vagina [nTPM]":"14.7","Tissue RNA - white matter [nTPM]":"12.7","Cell RNA - A-431 [nTPM]":"9.7","Cell RNA - A549 [nTPM]":"4.3","Cell RNA - AF22 [nTPM]":"10.3","Cell RNA - AN3-CA [nTPM]":"10.1","Cell RNA - ASC diff [nTPM]":"29.4","Cell RNA - ASC TERT1 [nTPM]":"20.4","Cell RNA - BEWO [nTPM]":"5.6","Cell RNA - BJ [nTPM]":"10.4","Cell RNA - BJ hTERT+ [nTPM]":"9.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.4","Cell RNA - CACO-2 [nTPM]":"6.5","Cell RNA - CAPAN-2 [nTPM]":"19.5","Cell RNA - Daudi [nTPM]":"21.2","Cell RNA - EFO-21 [nTPM]":"11.7","Cell RNA - fHDF\/TERT166 [nTPM]":"11.0","Cell RNA - GAMG [nTPM]":"11.1","Cell RNA - HaCaT [nTPM]":"7.0","Cell RNA - HAP1 [nTPM]":"5.3","Cell RNA - HBEC3-KT [nTPM]":"7.9","Cell RNA - HBF TERT88 [nTPM]":"3.9","Cell RNA - HDLM-2 [nTPM]":"6.6","Cell RNA - HEK 293 [nTPM]":"17.1","Cell RNA - HEL [nTPM]":"12.3","Cell RNA - HeLa [nTPM]":"5.2","Cell RNA - Hep G2 [nTPM]":"15.8","Cell RNA - HHSteC [nTPM]":"9.2","Cell RNA - HL-60 [nTPM]":"23.7","Cell RNA - HMC-1 [nTPM]":"6.1","Cell RNA - HSkMC [nTPM]":"17.6","Cell RNA - hTCEpi [nTPM]":"14.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.4","Cell RNA - hTERT-HME1 [nTPM]":"5.3","Cell RNA - hTERT-RPE1 [nTPM]":"7.8","Cell RNA - HUVEC TERT2 [nTPM]":"14.4","Cell RNA - JURKAT [nTPM]":"38.5","Cell RNA - K-562 [nTPM]":"21.2","Cell RNA - Karpas-707 [nTPM]":"47.7","Cell RNA - LHCN-M2 [nTPM]":"21.1","Cell RNA - MCF7 [nTPM]":"10.8","Cell RNA - MOLT-4 [nTPM]":"36.0","Cell RNA - NB-4 [nTPM]":"10.3","Cell RNA - NTERA-2 [nTPM]":"13.0","Cell RNA - OE19 [nTPM]":"53.2","Cell RNA - PC-3 [nTPM]":"9.3","Cell RNA - REH [nTPM]":"11.4","Cell RNA - RH-30 [nTPM]":"3.3","Cell RNA - RPMI-8226 [nTPM]":"14.0","Cell RNA - RPTEC TERT1 [nTPM]":"12.8","Cell RNA - RT4 [nTPM]":"7.9","Cell RNA - SCLC-21H [nTPM]":"16.0","Cell RNA - SH-SY5Y [nTPM]":"9.1","Cell RNA - SiHa [nTPM]":"10.7","Cell RNA - SK-BR-3 [nTPM]":"79.6","Cell RNA - SK-MEL-30 [nTPM]":"8.3","Cell RNA - SuSa [nTPM]":"9.0","Cell RNA - T-47d [nTPM]":"9.4","Cell RNA - THP-1 [nTPM]":"17.9","Cell RNA - TIME [nTPM]":"8.3","Cell RNA - U-138 MG [nTPM]":"25.0","Cell RNA - U-2 OS [nTPM]":"4.7","Cell RNA - U-2197 [nTPM]":"2.0","Cell RNA - U-251 MG [nTPM]":"8.1","Cell RNA - U-266\/70 [nTPM]":"28.6","Cell RNA - U-266\/84 [nTPM]":"15.8","Cell RNA - U-698 [nTPM]":"7.9","Cell RNA - U-87 MG [nTPM]":"34.1","Cell RNA - U-937 [nTPM]":"29.5","Cell RNA - WM-115 [nTPM]":"25.9","Blood RNA - basophil [nTPM]":"25.6","Blood RNA - classical monocyte [nTPM]":"35.8","Blood RNA - eosinophil [nTPM]":"11.7","Blood RNA - gdT-cell [nTPM]":"16.1","Blood RNA - intermediate monocyte [nTPM]":"56.5","Blood RNA - MAIT T-cell [nTPM]":"18.6","Blood RNA - memory B-cell [nTPM]":"12.5","Blood RNA - memory CD4 T-cell [nTPM]":"12.0","Blood RNA - memory CD8 T-cell [nTPM]":"15.2","Blood RNA - myeloid DC [nTPM]":"30.2","Blood RNA - naive B-cell [nTPM]":"12.7","Blood RNA - naive CD4 T-cell [nTPM]":"10.2","Blood RNA - naive CD8 T-cell [nTPM]":"14.4","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"8.6","Blood RNA - non-classical monocyte [nTPM]":"59.5","Blood RNA - plasmacytoid DC [nTPM]":"61.7","Blood RNA - T-reg [nTPM]":"12.5","Blood RNA - total PBMC [nTPM]":"23.1","Brain RNA - amygdala [nTPM]":"10.4","Brain RNA - basal ganglia [nTPM]":"11.5","Brain RNA - cerebellum [nTPM]":"11.0","Brain RNA - cerebral cortex [nTPM]":"12.4","Brain RNA - hippocampal formation [nTPM]":"10.7","Brain RNA - hypothalamus [nTPM]":"10.1","Brain RNA - medulla oblongata [nTPM]":"11.0","Brain RNA - midbrain [nTPM]":"11.2","Brain RNA - pons [nTPM]":"10.8","Brain RNA - spinal cord [nTPM]":"10.9","Brain RNA - thalamus [nTPM]":"10.9","Brain RNA - white matter [nTPM]":"12.7","Single Cell Type RNA - Adipocytes [nTPM]":"25.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.9","Single Cell Type RNA - Astrocytes [nTPM]":"4.6","Single Cell Type RNA - B-cells [nTPM]":"7.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"245.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"4.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"43.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"29.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"34.3","Single Cell Type RNA - Club cells [nTPM]":"245.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.0","Single Cell Type RNA - dendritic cells [nTPM]":"21.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"93.4","Single Cell Type RNA - Early spermatids [nTPM]":"3.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"51.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"31.0","Single Cell Type RNA - Endothelial cells [nTPM]":"19.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.0","Single Cell Type RNA - Erythroid cells [nTPM]":"14.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"105.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"106.0","Single Cell Type RNA - Fibroblasts [nTPM]":"16.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"105.9","Single Cell Type RNA - granulocytes [nTPM]":"14.0","Single Cell Type RNA - Granulosa cells [nTPM]":"6.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.5","Single Cell Type RNA - Hepatocytes [nTPM]":"18.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"63.4","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"22.6","Single Cell Type RNA - Ionocytes [nTPM]":"57.0","Single Cell Type RNA - Kupffer cells [nTPM]":"32.4","Single Cell Type RNA - Langerhans cells [nTPM]":"34.1","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"27.6","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"31.3","Single Cell Type RNA - Muller glia cells [nTPM]":"21.9","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"23.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"155.5","Single Cell Type RNA - Paneth cells [nTPM]":"10.0","Single Cell Type RNA - Peritubular cells [nTPM]":"5.7","Single Cell Type RNA - Plasma cells [nTPM]":"16.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"195.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.9","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"28.2","Single Cell Type RNA - Spermatocytes [nTPM]":"3.5","Single Cell Type RNA - Spermatogonia [nTPM]":"20.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"32.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"29.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.5","Single Cell Type RNA - T-cells [nTPM]":"7.2","Single Cell Type RNA - Theca cells [nTPM]":"15.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.3","Single Cell Type RNA - Urothelial cells [nTPM]":"108.6"},{"Gene":"SRP54","Gene synonym":[],"Ensembl":"ENSG00000100883","Gene description":"Signal recognition particle 54","Uniprot":["P61011"],"Chromosome":"14","Position":"34981957-35029686","Protein class":["Disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":["Hydrolase","Ribonucleoprotein","RNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"327.3","Late spermatids":"901.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048977","HPA062044"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA048977":"AB_2680583","HPA062044":"AB_2684668"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-3"},"Tissue RNA - adipose tissue [nTPM]":"22.8","Tissue RNA - adrenal gland [nTPM]":"33.1","Tissue RNA - amygdala [nTPM]":"17.1","Tissue RNA - appendix [nTPM]":"30.2","Tissue RNA - basal ganglia [nTPM]":"18.1","Tissue RNA - bone marrow [nTPM]":"17.4","Tissue RNA - breast [nTPM]":"28.7","Tissue RNA - cerebellum [nTPM]":"19.3","Tissue RNA - cerebral cortex [nTPM]":"22.5","Tissue RNA - cervix [nTPM]":"32.5","Tissue RNA - choroid plexus [nTPM]":"20.9","Tissue RNA - colon [nTPM]":"28.1","Tissue RNA - duodenum [nTPM]":"25.8","Tissue RNA - endometrium 1 [nTPM]":"23.3","Tissue RNA - epididymis [nTPM]":"35.8","Tissue RNA - esophagus [nTPM]":"28.5","Tissue RNA - fallopian tube [nTPM]":"22.0","Tissue RNA - gallbladder [nTPM]":"23.2","Tissue RNA - heart muscle [nTPM]":"32.1","Tissue RNA - hippocampal formation [nTPM]":"17.6","Tissue RNA - hypothalamus [nTPM]":"21.3","Tissue RNA - kidney [nTPM]":"35.3","Tissue RNA - liver [nTPM]":"61.9","Tissue RNA - lung [nTPM]":"25.0","Tissue RNA - lymph node [nTPM]":"34.6","Tissue RNA - medulla oblongata [nTPM]":"19.8","Tissue RNA - midbrain [nTPM]":"19.2","Tissue RNA - ovary [nTPM]":"22.7","Tissue RNA - pancreas [nTPM]":"55.0","Tissue RNA - parathyroid gland [nTPM]":"39.7","Tissue RNA - pituitary gland [nTPM]":"36.2","Tissue RNA - placenta [nTPM]":"29.5","Tissue RNA - pons [nTPM]":"20.5","Tissue RNA - prostate [nTPM]":"31.2","Tissue RNA - rectum [nTPM]":"29.5","Tissue RNA - retina [nTPM]":"24.2","Tissue RNA - salivary gland [nTPM]":"60.3","Tissue RNA - seminal vesicle [nTPM]":"28.7","Tissue RNA - skeletal muscle [nTPM]":"39.8","Tissue RNA - skin 1 [nTPM]":"26.1","Tissue RNA - small intestine [nTPM]":"26.8","Tissue RNA - smooth muscle [nTPM]":"23.5","Tissue RNA - spinal cord [nTPM]":"20.0","Tissue RNA - spleen [nTPM]":"28.4","Tissue RNA - stomach 1 [nTPM]":"30.4","Tissue RNA - testis [nTPM]":"44.0","Tissue RNA - thalamus [nTPM]":"18.1","Tissue RNA - thymus [nTPM]":"35.5","Tissue RNA - thyroid gland [nTPM]":"30.9","Tissue RNA - tongue [nTPM]":"33.7","Tissue RNA - tonsil [nTPM]":"42.6","Tissue RNA - urinary bladder [nTPM]":"34.8","Tissue RNA - vagina [nTPM]":"23.1","Tissue RNA - white matter [nTPM]":"21.4","Cell RNA - A-431 [nTPM]":"59.3","Cell RNA - A549 [nTPM]":"66.9","Cell RNA - AF22 [nTPM]":"56.7","Cell RNA - AN3-CA [nTPM]":"54.9","Cell RNA - ASC diff [nTPM]":"62.8","Cell RNA - ASC TERT1 [nTPM]":"61.3","Cell RNA - BEWO [nTPM]":"67.8","Cell RNA - BJ [nTPM]":"83.2","Cell RNA - BJ hTERT+ [nTPM]":"78.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"87.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"107.0","Cell RNA - CACO-2 [nTPM]":"71.3","Cell RNA - CAPAN-2 [nTPM]":"62.8","Cell RNA - Daudi [nTPM]":"75.8","Cell RNA - EFO-21 [nTPM]":"77.5","Cell RNA - fHDF\/TERT166 [nTPM]":"81.4","Cell RNA - GAMG [nTPM]":"75.8","Cell RNA - HaCaT [nTPM]":"56.1","Cell RNA - HAP1 [nTPM]":"79.0","Cell RNA - HBEC3-KT [nTPM]":"66.7","Cell RNA - HBF TERT88 [nTPM]":"125.6","Cell RNA - HDLM-2 [nTPM]":"87.5","Cell RNA - HEK 293 [nTPM]":"37.8","Cell RNA - HEL [nTPM]":"70.9","Cell RNA - HeLa [nTPM]":"54.6","Cell RNA - Hep G2 [nTPM]":"184.6","Cell RNA - HHSteC [nTPM]":"92.7","Cell RNA - HL-60 [nTPM]":"70.5","Cell RNA - HMC-1 [nTPM]":"65.4","Cell RNA - HSkMC [nTPM]":"51.5","Cell RNA - hTCEpi [nTPM]":"64.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"63.5","Cell RNA - hTERT-HME1 [nTPM]":"102.3","Cell RNA - hTERT-RPE1 [nTPM]":"66.1","Cell RNA - HUVEC TERT2 [nTPM]":"88.8","Cell RNA - JURKAT [nTPM]":"64.9","Cell RNA - K-562 [nTPM]":"61.7","Cell RNA - Karpas-707 [nTPM]":"82.7","Cell RNA - LHCN-M2 [nTPM]":"93.1","Cell RNA - MCF7 [nTPM]":"98.8","Cell RNA - MOLT-4 [nTPM]":"81.9","Cell RNA - NB-4 [nTPM]":"42.4","Cell RNA - NTERA-2 [nTPM]":"45.0","Cell RNA - OE19 [nTPM]":"96.1","Cell RNA - PC-3 [nTPM]":"61.3","Cell RNA - REH [nTPM]":"58.5","Cell RNA - RH-30 [nTPM]":"72.2","Cell RNA - RPMI-8226 [nTPM]":"67.4","Cell RNA - RPTEC TERT1 [nTPM]":"104.9","Cell RNA - RT4 [nTPM]":"89.3","Cell RNA - SCLC-21H [nTPM]":"48.9","Cell RNA - SH-SY5Y [nTPM]":"59.4","Cell RNA - SiHa [nTPM]":"59.3","Cell RNA - SK-BR-3 [nTPM]":"76.7","Cell RNA - SK-MEL-30 [nTPM]":"74.6","Cell RNA - SuSa [nTPM]":"71.4","Cell RNA - T-47d [nTPM]":"99.4","Cell RNA - THP-1 [nTPM]":"49.7","Cell RNA - TIME [nTPM]":"66.6","Cell RNA - U-138 MG [nTPM]":"48.7","Cell RNA - U-2 OS [nTPM]":"51.0","Cell RNA - U-2197 [nTPM]":"62.8","Cell RNA - U-251 MG [nTPM]":"57.1","Cell RNA - U-266\/70 [nTPM]":"73.2","Cell RNA - U-266\/84 [nTPM]":"108.3","Cell RNA - U-698 [nTPM]":"101.1","Cell RNA - U-87 MG [nTPM]":"36.8","Cell RNA - U-937 [nTPM]":"45.9","Cell RNA - WM-115 [nTPM]":"63.5","Blood RNA - basophil [nTPM]":"23.8","Blood RNA - classical monocyte [nTPM]":"27.4","Blood RNA - eosinophil [nTPM]":"39.2","Blood RNA - gdT-cell [nTPM]":"31.0","Blood RNA - intermediate monocyte [nTPM]":"35.0","Blood RNA - MAIT T-cell [nTPM]":"39.6","Blood RNA - memory B-cell [nTPM]":"25.6","Blood RNA - memory CD4 T-cell [nTPM]":"31.4","Blood RNA - memory CD8 T-cell [nTPM]":"34.0","Blood RNA - myeloid DC [nTPM]":"32.8","Blood RNA - naive B-cell [nTPM]":"25.8","Blood RNA - naive CD4 T-cell [nTPM]":"28.7","Blood RNA - naive CD8 T-cell [nTPM]":"28.3","Blood RNA - neutrophil [nTPM]":"27.1","Blood RNA - NK-cell [nTPM]":"42.1","Blood RNA - non-classical monocyte [nTPM]":"47.0","Blood RNA - plasmacytoid DC [nTPM]":"21.9","Blood RNA - T-reg [nTPM]":"48.2","Blood RNA - total PBMC [nTPM]":"30.5","Brain RNA - amygdala [nTPM]":"17.1","Brain RNA - basal ganglia [nTPM]":"18.1","Brain RNA - cerebellum [nTPM]":"19.3","Brain RNA - cerebral cortex [nTPM]":"22.5","Brain RNA - hippocampal formation [nTPM]":"17.6","Brain RNA - hypothalamus [nTPM]":"21.3","Brain RNA - medulla oblongata [nTPM]":"19.8","Brain RNA - midbrain [nTPM]":"19.2","Brain RNA - pons [nTPM]":"20.5","Brain RNA - spinal cord [nTPM]":"20.0","Brain RNA - thalamus [nTPM]":"18.1","Brain RNA - white matter [nTPM]":"21.4","Single Cell Type RNA - Adipocytes [nTPM]":"40.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"49.3","Single Cell Type RNA - Astrocytes [nTPM]":"25.5","Single Cell Type RNA - B-cells [nTPM]":"63.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"40.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"56.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"74.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"37.5","Single Cell Type RNA - Bipolar cells [nTPM]":"37.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"40.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"29.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"41.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"34.3","Single Cell Type RNA - Club cells [nTPM]":"81.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"58.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"67.3","Single Cell Type RNA - dendritic cells [nTPM]":"59.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"39.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"64.6","Single Cell Type RNA - Ductal cells [nTPM]":"73.2","Single Cell Type RNA - Early spermatids [nTPM]":"327.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"53.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"43.9","Single Cell Type RNA - Endothelial cells [nTPM]":"40.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"44.9","Single Cell Type RNA - Erythroid cells [nTPM]":"36.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"79.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"75.6","Single Cell Type RNA - Fibroblasts [nTPM]":"45.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"38.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"64.3","Single Cell Type RNA - granulocytes [nTPM]":"47.5","Single Cell Type RNA - Granulosa cells [nTPM]":"37.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"36.4","Single Cell Type RNA - Hepatocytes [nTPM]":"110.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"49.7","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"26.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"48.7","Single Cell Type RNA - Ionocytes [nTPM]":"87.5","Single Cell Type RNA - Kupffer cells [nTPM]":"39.0","Single Cell Type RNA - Langerhans cells [nTPM]":"43.6","Single Cell Type RNA - Late spermatids [nTPM]":"901.8","Single Cell Type RNA - Leydig cells [nTPM]":"38.5","Single Cell Type RNA - Macrophages [nTPM]":"47.4","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"24.4","Single Cell Type RNA - monocytes [nTPM]":"56.1","Single Cell Type RNA - Muller glia cells [nTPM]":"44.3","Single Cell Type RNA - NK-cells [nTPM]":"41.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"27.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"54.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"55.1","Single Cell Type RNA - Paneth cells [nTPM]":"34.0","Single Cell Type RNA - Peritubular cells [nTPM]":"37.6","Single Cell Type RNA - Plasma cells [nTPM]":"133.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"60.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"39.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"79.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"93.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"50.1","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"38.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"46.1","Single Cell Type RNA - Spermatocytes [nTPM]":"95.4","Single Cell Type RNA - Spermatogonia [nTPM]":"76.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"36.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"50.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"94.0","Single Cell Type RNA - T-cells [nTPM]":"64.7","Single Cell Type RNA - Theca cells [nTPM]":"43.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"31.6","Single Cell Type RNA - Urothelial cells [nTPM]":"64.5"},{"Gene":"SRP72","Gene synonym":[],"Ensembl":"ENSG00000174780","Gene description":"Signal recognition particle 72","Uniprot":["O76094"],"Chromosome":"4","Position":"56467617-56503681","Protein class":["Disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":["Ribonucleoprotein"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034621"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"23000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA034621":"AB_10601593"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.83e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.25e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Tissue RNA - adipose tissue [nTPM]":"37.7","Tissue RNA - adrenal gland [nTPM]":"31.6","Tissue RNA - amygdala [nTPM]":"13.9","Tissue RNA - appendix [nTPM]":"41.2","Tissue RNA - basal ganglia [nTPM]":"15.0","Tissue RNA - bone marrow [nTPM]":"73.5","Tissue RNA - breast [nTPM]":"49.8","Tissue RNA - cerebellum [nTPM]":"15.1","Tissue RNA - cerebral cortex [nTPM]":"18.1","Tissue RNA - cervix [nTPM]":"41.4","Tissue RNA - choroid plexus [nTPM]":"20.5","Tissue RNA - colon [nTPM]":"39.1","Tissue RNA - duodenum [nTPM]":"29.3","Tissue RNA - endometrium 1 [nTPM]":"40.8","Tissue RNA - epididymis [nTPM]":"29.5","Tissue RNA - esophagus [nTPM]":"42.3","Tissue RNA - fallopian tube [nTPM]":"33.0","Tissue RNA - gallbladder [nTPM]":"33.5","Tissue RNA - heart muscle [nTPM]":"25.2","Tissue RNA - hippocampal formation [nTPM]":"14.2","Tissue RNA - hypothalamus [nTPM]":"19.1","Tissue RNA - kidney [nTPM]":"33.4","Tissue RNA - liver [nTPM]":"45.4","Tissue RNA - lung [nTPM]":"32.1","Tissue RNA - lymph node [nTPM]":"49.5","Tissue RNA - medulla oblongata [nTPM]":"14.9","Tissue RNA - midbrain [nTPM]":"18.8","Tissue RNA - ovary [nTPM]":"45.0","Tissue RNA - pancreas [nTPM]":"47.7","Tissue RNA - parathyroid gland [nTPM]":"43.4","Tissue RNA - pituitary gland [nTPM]":"16.4","Tissue RNA - placenta [nTPM]":"48.3","Tissue RNA - pons [nTPM]":"16.8","Tissue RNA - prostate [nTPM]":"31.1","Tissue RNA - rectum [nTPM]":"41.1","Tissue RNA - retina [nTPM]":"27.3","Tissue RNA - salivary gland [nTPM]":"43.8","Tissue RNA - seminal vesicle [nTPM]":"32.7","Tissue RNA - skeletal muscle [nTPM]":"33.3","Tissue RNA - skin 1 [nTPM]":"34.3","Tissue RNA - small intestine [nTPM]":"31.6","Tissue RNA - smooth muscle [nTPM]":"44.6","Tissue RNA - spinal cord [nTPM]":"15.9","Tissue RNA - spleen [nTPM]":"39.1","Tissue RNA - stomach 1 [nTPM]":"33.6","Tissue RNA - testis [nTPM]":"27.2","Tissue RNA - thalamus [nTPM]":"14.9","Tissue RNA - thymus [nTPM]":"52.8","Tissue RNA - thyroid gland [nTPM]":"54.3","Tissue RNA - tongue [nTPM]":"35.7","Tissue RNA - tonsil [nTPM]":"55.6","Tissue RNA - urinary bladder [nTPM]":"46.6","Tissue RNA - vagina [nTPM]":"23.7","Tissue RNA - white matter [nTPM]":"18.6","Cell RNA - A-431 [nTPM]":"109.1","Cell RNA - A549 [nTPM]":"82.0","Cell RNA - AF22 [nTPM]":"101.6","Cell RNA - AN3-CA [nTPM]":"98.7","Cell RNA - ASC diff [nTPM]":"63.2","Cell RNA - ASC TERT1 [nTPM]":"90.0","Cell RNA - BEWO [nTPM]":"98.0","Cell RNA - BJ [nTPM]":"157.2","Cell RNA - BJ hTERT+ [nTPM]":"125.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"129.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"102.7","Cell RNA - CACO-2 [nTPM]":"91.2","Cell RNA - CAPAN-2 [nTPM]":"120.5","Cell RNA - Daudi [nTPM]":"167.6","Cell RNA - EFO-21 [nTPM]":"105.6","Cell RNA - fHDF\/TERT166 [nTPM]":"132.2","Cell RNA - GAMG [nTPM]":"68.2","Cell RNA - HaCaT [nTPM]":"61.1","Cell RNA - HAP1 [nTPM]":"126.9","Cell RNA - HBEC3-KT [nTPM]":"133.4","Cell RNA - HBF TERT88 [nTPM]":"152.3","Cell RNA - HDLM-2 [nTPM]":"44.3","Cell RNA - HEK 293 [nTPM]":"74.0","Cell RNA - HEL [nTPM]":"146.4","Cell RNA - HeLa [nTPM]":"90.3","Cell RNA - Hep G2 [nTPM]":"86.0","Cell RNA - HHSteC [nTPM]":"115.7","Cell RNA - HL-60 [nTPM]":"284.4","Cell RNA - HMC-1 [nTPM]":"116.3","Cell RNA - HSkMC [nTPM]":"85.8","Cell RNA - hTCEpi [nTPM]":"175.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"138.0","Cell RNA - hTERT-HME1 [nTPM]":"243.3","Cell RNA - hTERT-RPE1 [nTPM]":"112.1","Cell RNA - HUVEC TERT2 [nTPM]":"117.1","Cell RNA - JURKAT [nTPM]":"126.4","Cell RNA - K-562 [nTPM]":"216.1","Cell RNA - Karpas-707 [nTPM]":"157.0","Cell RNA - LHCN-M2 [nTPM]":"124.9","Cell RNA - MCF7 [nTPM]":"84.2","Cell RNA - MOLT-4 [nTPM]":"168.6","Cell RNA - NB-4 [nTPM]":"73.9","Cell RNA - NTERA-2 [nTPM]":"88.2","Cell RNA - OE19 [nTPM]":"135.1","Cell RNA - PC-3 [nTPM]":"86.1","Cell RNA - REH [nTPM]":"149.2","Cell RNA - RH-30 [nTPM]":"81.9","Cell RNA - RPMI-8226 [nTPM]":"127.0","Cell RNA - RPTEC TERT1 [nTPM]":"88.5","Cell RNA - RT4 [nTPM]":"101.7","Cell RNA - SCLC-21H [nTPM]":"62.9","Cell RNA - SH-SY5Y [nTPM]":"104.5","Cell RNA - SiHa [nTPM]":"99.8","Cell RNA - SK-BR-3 [nTPM]":"193.4","Cell RNA - SK-MEL-30 [nTPM]":"88.5","Cell RNA - SuSa [nTPM]":"81.3","Cell RNA - T-47d [nTPM]":"77.0","Cell RNA - THP-1 [nTPM]":"102.3","Cell RNA - TIME [nTPM]":"142.7","Cell RNA - U-138 MG [nTPM]":"106.8","Cell RNA - U-2 OS [nTPM]":"143.3","Cell RNA - U-2197 [nTPM]":"110.4","Cell RNA - U-251 MG [nTPM]":"165.2","Cell RNA - U-266\/70 [nTPM]":"111.8","Cell RNA - U-266\/84 [nTPM]":"56.9","Cell RNA - U-698 [nTPM]":"181.2","Cell RNA - U-87 MG [nTPM]":"114.9","Cell RNA - U-937 [nTPM]":"148.3","Cell RNA - WM-115 [nTPM]":"132.2","Blood RNA - basophil [nTPM]":"43.0","Blood RNA - classical monocyte [nTPM]":"64.3","Blood RNA - eosinophil [nTPM]":"38.7","Blood RNA - gdT-cell [nTPM]":"50.4","Blood RNA - intermediate monocyte [nTPM]":"70.8","Blood RNA - MAIT T-cell [nTPM]":"65.1","Blood RNA - memory B-cell [nTPM]":"52.8","Blood RNA - memory CD4 T-cell [nTPM]":"50.9","Blood RNA - memory CD8 T-cell [nTPM]":"51.1","Blood RNA - myeloid DC [nTPM]":"82.1","Blood RNA - naive B-cell [nTPM]":"48.5","Blood RNA - naive CD4 T-cell [nTPM]":"49.4","Blood RNA - naive CD8 T-cell [nTPM]":"49.9","Blood RNA - neutrophil [nTPM]":"8.4","Blood RNA - NK-cell [nTPM]":"59.5","Blood RNA - non-classical monocyte [nTPM]":"57.5","Blood RNA - plasmacytoid DC [nTPM]":"61.4","Blood RNA - T-reg [nTPM]":"60.8","Blood RNA - total PBMC [nTPM]":"58.7","Brain RNA - amygdala [nTPM]":"13.9","Brain RNA - basal ganglia [nTPM]":"15.0","Brain RNA - cerebellum [nTPM]":"15.1","Brain RNA - cerebral cortex [nTPM]":"18.1","Brain RNA - hippocampal formation [nTPM]":"14.2","Brain RNA - hypothalamus [nTPM]":"19.1","Brain RNA - medulla oblongata [nTPM]":"14.9","Brain RNA - midbrain [nTPM]":"18.8","Brain RNA - pons [nTPM]":"16.8","Brain RNA - spinal cord [nTPM]":"15.9","Brain RNA - thalamus [nTPM]":"14.9","Brain RNA - white matter [nTPM]":"18.6","Single Cell Type RNA - Adipocytes [nTPM]":"78.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"73.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"72.5","Single Cell Type RNA - Astrocytes [nTPM]":"17.0","Single Cell Type RNA - B-cells [nTPM]":"84.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"97.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"93.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"103.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"47.3","Single Cell Type RNA - Bipolar cells [nTPM]":"61.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"65.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"80.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"45.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"54.3","Single Cell Type RNA - Club cells [nTPM]":"87.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"120.8","Single Cell Type RNA - dendritic cells [nTPM]":"97.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"30.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"66.5","Single Cell Type RNA - Ductal cells [nTPM]":"121.1","Single Cell Type RNA - Early spermatids [nTPM]":"86.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"38.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"87.2","Single Cell Type RNA - Endothelial cells [nTPM]":"83.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"53.2","Single Cell Type RNA - Erythroid cells [nTPM]":"113.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"30.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"131.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"197.3","Single Cell Type RNA - Fibroblasts [nTPM]":"84.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"39.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"73.3","Single Cell Type RNA - granulocytes [nTPM]":"101.9","Single Cell Type RNA - Granulosa cells [nTPM]":"94.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"63.9","Single Cell Type RNA - Hepatocytes [nTPM]":"80.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"100.4","Single Cell Type RNA - Horizontal cells [nTPM]":"57.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"32.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"94.8","Single Cell Type RNA - Ionocytes [nTPM]":"69.2","Single Cell Type RNA - Kupffer cells [nTPM]":"109.4","Single Cell Type RNA - Langerhans cells [nTPM]":"78.9","Single Cell Type RNA - Late spermatids [nTPM]":"116.1","Single Cell Type RNA - Leydig cells [nTPM]":"65.3","Single Cell Type RNA - Macrophages [nTPM]":"83.4","Single Cell Type RNA - Melanocytes [nTPM]":"58.7","Single Cell Type RNA - Microglial cells [nTPM]":"28.1","Single Cell Type RNA - monocytes [nTPM]":"122.4","Single Cell Type RNA - Muller glia cells [nTPM]":"54.5","Single Cell Type RNA - NK-cells [nTPM]":"72.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"29.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"35.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"111.8","Single Cell Type RNA - Paneth cells [nTPM]":"48.7","Single Cell Type RNA - Peritubular cells [nTPM]":"66.5","Single Cell Type RNA - Plasma cells [nTPM]":"156.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"131.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"43.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"71.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"54.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"37.7","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"92.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"106.7","Single Cell Type RNA - Spermatocytes [nTPM]":"48.2","Single Cell Type RNA - Spermatogonia [nTPM]":"86.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"73.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"100.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"166.5","Single Cell Type RNA - T-cells [nTPM]":"71.1","Single Cell Type RNA - Theca cells [nTPM]":"111.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"89.0","Single Cell Type RNA - Urothelial cells [nTPM]":"115.2"},{"Gene":"ST14","Gene synonym":["HAI","MT-SP1","PRSS14","SNC19","TMPRSS14"],"Ensembl":"ENSG00000149418","Gene description":"ST14 transmembrane serine protease matriptase","Uniprot":["Q9Y5Y6"],"Chromosome":"11","Position":"130159782-130210362","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Cancer-related genes","Disease variant","Hypotrichosis","Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"144.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"489.4","Paneth cells":"327.2","Proximal enterocytes":"251.9","Undifferentiated cells":"216.9","Urothelial cells":"286.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"thalamus":"10.0"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"plasmacytoid DC":"25.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"25.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"224.2","CAPAN-2":"443.0","HaCaT":"311.4","OE19":"240.4","RPMI-8226":"301.2","SK-BR-3":"203.1","T-47d":"308.3","U-698":"218.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047014","HPA056258"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1100000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA047014":"AB_2679902","HPA056258":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.03e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.3","Tissue RNA - adrenal gland [nTPM]":"3.9","Tissue RNA - amygdala [nTPM]":"0.8","Tissue RNA - appendix [nTPM]":"26.7","Tissue RNA - basal ganglia [nTPM]":"1.2","Tissue RNA - bone marrow [nTPM]":"4.3","Tissue RNA - breast [nTPM]":"17.7","Tissue RNA - cerebellum [nTPM]":"1.8","Tissue RNA - cerebral cortex [nTPM]":"2.9","Tissue RNA - cervix [nTPM]":"18.6","Tissue RNA - choroid plexus [nTPM]":"1.2","Tissue RNA - colon [nTPM]":"124.7","Tissue RNA - duodenum [nTPM]":"130.7","Tissue RNA - endometrium 1 [nTPM]":"5.7","Tissue RNA - epididymis [nTPM]":"21.8","Tissue RNA - esophagus [nTPM]":"104.5","Tissue RNA - fallopian tube [nTPM]":"37.1","Tissue RNA - gallbladder [nTPM]":"32.6","Tissue RNA - heart muscle [nTPM]":"0.9","Tissue RNA - hippocampal formation [nTPM]":"0.9","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"43.2","Tissue RNA - liver [nTPM]":"6.3","Tissue RNA - lung [nTPM]":"18.5","Tissue RNA - lymph node [nTPM]":"11.9","Tissue RNA - medulla oblongata [nTPM]":"1.8","Tissue RNA - midbrain [nTPM]":"1.7","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"59.2","Tissue RNA - parathyroid gland [nTPM]":"36.5","Tissue RNA - pituitary gland [nTPM]":"19.1","Tissue RNA - placenta [nTPM]":"15.1","Tissue RNA - pons [nTPM]":"3.1","Tissue RNA - prostate [nTPM]":"23.1","Tissue RNA - rectum [nTPM]":"60.1","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"58.7","Tissue RNA - seminal vesicle [nTPM]":"23.6","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"50.2","Tissue RNA - small intestine [nTPM]":"144.8","Tissue RNA - smooth muscle [nTPM]":"5.4","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"9.1","Tissue RNA - stomach 1 [nTPM]":"64.9","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"10.0","Tissue RNA - thymus [nTPM]":"10.5","Tissue RNA - thyroid gland [nTPM]":"28.6","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"20.9","Tissue RNA - urinary bladder [nTPM]":"34.8","Tissue RNA - vagina [nTPM]":"42.5","Tissue RNA - white matter [nTPM]":"2.7","Cell RNA - A-431 [nTPM]":"167.2","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.6","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"86.4","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"224.2","Cell RNA - CAPAN-2 [nTPM]":"443.0","Cell RNA - Daudi [nTPM]":"163.6","Cell RNA - EFO-21 [nTPM]":"16.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"311.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"99.3","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.9","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"22.0","Cell RNA - HMC-1 [nTPM]":"0.8","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"49.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"128.5","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"1.1","Cell RNA - NTERA-2 [nTPM]":"1.7","Cell RNA - OE19 [nTPM]":"240.4","Cell RNA - PC-3 [nTPM]":"0.9","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"301.2","Cell RNA - RPTEC TERT1 [nTPM]":"28.8","Cell RNA - RT4 [nTPM]":"134.2","Cell RNA - SCLC-21H [nTPM]":"17.8","Cell RNA - SH-SY5Y [nTPM]":"0.4","Cell RNA - SiHa [nTPM]":"1.5","Cell RNA - SK-BR-3 [nTPM]":"203.1","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"1.6","Cell RNA - T-47d [nTPM]":"308.3","Cell RNA - THP-1 [nTPM]":"32.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.4","Cell RNA - U-2 OS [nTPM]":"2.7","Cell RNA - U-2197 [nTPM]":"0.7","Cell RNA - U-251 MG [nTPM]":"0.7","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"218.5","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"50.4","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"3.6","Blood RNA - eosinophil [nTPM]":"3.4","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"2.2","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"5.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"6.2","Blood RNA - naive B-cell [nTPM]":"3.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"25.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"0.8","Brain RNA - basal ganglia [nTPM]":"1.2","Brain RNA - cerebellum [nTPM]":"1.8","Brain RNA - cerebral cortex [nTPM]":"2.9","Brain RNA - hippocampal formation [nTPM]":"0.9","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"1.8","Brain RNA - midbrain [nTPM]":"1.7","Brain RNA - pons [nTPM]":"3.1","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"10.0","Brain RNA - white matter [nTPM]":"2.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"28.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"18.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"40.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"51.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"45.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"36.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"77.2","Single Cell Type RNA - Club cells [nTPM]":"61.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"62.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"45.6","Single Cell Type RNA - dendritic cells [nTPM]":"26.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"489.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"115.8","Single Cell Type RNA - Early spermatids [nTPM]":"37.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"43.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.7","Single Cell Type RNA - Endothelial cells [nTPM]":"1.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"123.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"91.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.6","Single Cell Type RNA - Fibroblasts [nTPM]":"3.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"112.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"79.6","Single Cell Type RNA - granulocytes [nTPM]":"11.4","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"2.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"58.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"201.0","Single Cell Type RNA - Ionocytes [nTPM]":"148.5","Single Cell Type RNA - Kupffer cells [nTPM]":"22.7","Single Cell Type RNA - Langerhans cells [nTPM]":"13.2","Single Cell Type RNA - Late spermatids [nTPM]":"13.9","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"28.0","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"13.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"153.4","Single Cell Type RNA - Paneth cells [nTPM]":"327.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"5.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"108.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"251.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"76.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"61.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"43.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"39.7","Single Cell Type RNA - T-cells [nTPM]":"2.9","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"216.9","Single Cell Type RNA - Urothelial cells [nTPM]":"286.8"},{"Gene":"ST3GAL3","Gene synonym":["MRT12","SIAT6"],"Ensembl":"ENSG00000126091","Gene description":"ST3 beta-galactoside alpha-2,3-sialyltransferase 3","Uniprot":["Q11203"],"Chromosome":"1","Position":"43705824-43931165","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"88.0","tongue":"82.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"59.7","Excitatory neurons":"94.4","Granulosa cells":"52.5","Inhibitory neurons":"120.1","Microglial cells":"57.1","Oligodendrocyte precursor cells":"66.9","Oligodendrocytes":"66.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051102"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 29: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051102":"AB_2681344"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-2"},"Tissue RNA - adipose tissue [nTPM]":"12.9","Tissue RNA - adrenal gland [nTPM]":"14.7","Tissue RNA - amygdala [nTPM]":"28.5","Tissue RNA - appendix [nTPM]":"5.0","Tissue RNA - basal ganglia [nTPM]":"27.3","Tissue RNA - bone marrow [nTPM]":"11.0","Tissue RNA - breast [nTPM]":"11.0","Tissue RNA - cerebellum [nTPM]":"30.8","Tissue RNA - cerebral cortex [nTPM]":"32.5","Tissue RNA - cervix [nTPM]":"14.6","Tissue RNA - choroid plexus [nTPM]":"22.8","Tissue RNA - colon [nTPM]":"19.4","Tissue RNA - duodenum [nTPM]":"2.6","Tissue RNA - endometrium 1 [nTPM]":"16.7","Tissue RNA - epididymis [nTPM]":"9.8","Tissue RNA - esophagus [nTPM]":"8.3","Tissue RNA - fallopian tube [nTPM]":"12.8","Tissue RNA - gallbladder [nTPM]":"6.9","Tissue RNA - heart muscle [nTPM]":"26.1","Tissue RNA - hippocampal formation [nTPM]":"27.2","Tissue RNA - hypothalamus [nTPM]":"29.4","Tissue RNA - kidney [nTPM]":"9.9","Tissue RNA - liver [nTPM]":"13.5","Tissue RNA - lung [nTPM]":"8.7","Tissue RNA - lymph node [nTPM]":"6.1","Tissue RNA - medulla oblongata [nTPM]":"27.9","Tissue RNA - midbrain [nTPM]":"29.0","Tissue RNA - ovary [nTPM]":"14.9","Tissue RNA - pancreas [nTPM]":"8.0","Tissue RNA - parathyroid gland [nTPM]":"6.7","Tissue RNA - pituitary gland [nTPM]":"17.8","Tissue RNA - placenta [nTPM]":"6.5","Tissue RNA - pons [nTPM]":"29.2","Tissue RNA - prostate [nTPM]":"13.2","Tissue RNA - rectum [nTPM]":"4.4","Tissue RNA - retina [nTPM]":"24.5","Tissue RNA - salivary gland [nTPM]":"8.3","Tissue RNA - seminal vesicle [nTPM]":"13.3","Tissue RNA - skeletal muscle [nTPM]":"88.0","Tissue RNA - skin 1 [nTPM]":"7.0","Tissue RNA - small intestine [nTPM]":"6.6","Tissue RNA - smooth muscle [nTPM]":"13.1","Tissue RNA - spinal cord [nTPM]":"23.2","Tissue RNA - spleen [nTPM]":"7.6","Tissue RNA - stomach 1 [nTPM]":"9.6","Tissue RNA - testis [nTPM]":"22.6","Tissue RNA - thalamus [nTPM]":"30.8","Tissue RNA - thymus [nTPM]":"4.9","Tissue RNA - thyroid gland [nTPM]":"8.4","Tissue RNA - tongue [nTPM]":"82.9","Tissue RNA - tonsil [nTPM]":"3.7","Tissue RNA - urinary bladder [nTPM]":"16.7","Tissue RNA - vagina [nTPM]":"10.1","Tissue RNA - white matter [nTPM]":"28.1","Cell RNA - A-431 [nTPM]":"4.3","Cell RNA - A549 [nTPM]":"2.7","Cell RNA - AF22 [nTPM]":"23.4","Cell RNA - AN3-CA [nTPM]":"11.0","Cell RNA - ASC diff [nTPM]":"17.4","Cell RNA - ASC TERT1 [nTPM]":"21.9","Cell RNA - BEWO [nTPM]":"3.0","Cell RNA - BJ [nTPM]":"15.5","Cell RNA - BJ hTERT+ [nTPM]":"30.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.7","Cell RNA - CACO-2 [nTPM]":"2.6","Cell RNA - CAPAN-2 [nTPM]":"6.6","Cell RNA - Daudi [nTPM]":"7.0","Cell RNA - EFO-21 [nTPM]":"8.6","Cell RNA - fHDF\/TERT166 [nTPM]":"19.0","Cell RNA - GAMG [nTPM]":"7.7","Cell RNA - HaCaT [nTPM]":"3.8","Cell RNA - HAP1 [nTPM]":"2.8","Cell RNA - HBEC3-KT [nTPM]":"10.2","Cell RNA - HBF TERT88 [nTPM]":"15.7","Cell RNA - HDLM-2 [nTPM]":"8.7","Cell RNA - HEK 293 [nTPM]":"5.8","Cell RNA - HEL [nTPM]":"15.0","Cell RNA - HeLa [nTPM]":"10.6","Cell RNA - Hep G2 [nTPM]":"7.5","Cell RNA - HHSteC [nTPM]":"14.7","Cell RNA - HL-60 [nTPM]":"6.6","Cell RNA - HMC-1 [nTPM]":"7.1","Cell RNA - HSkMC [nTPM]":"12.1","Cell RNA - hTCEpi [nTPM]":"7.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.7","Cell RNA - hTERT-HME1 [nTPM]":"21.3","Cell RNA - hTERT-RPE1 [nTPM]":"26.1","Cell RNA - HUVEC TERT2 [nTPM]":"12.1","Cell RNA - JURKAT [nTPM]":"18.4","Cell RNA - K-562 [nTPM]":"8.8","Cell RNA - Karpas-707 [nTPM]":"13.1","Cell RNA - LHCN-M2 [nTPM]":"25.3","Cell RNA - MCF7 [nTPM]":"2.7","Cell RNA - MOLT-4 [nTPM]":"7.0","Cell RNA - NB-4 [nTPM]":"11.7","Cell RNA - NTERA-2 [nTPM]":"9.2","Cell RNA - OE19 [nTPM]":"1.0","Cell RNA - PC-3 [nTPM]":"8.1","Cell RNA - REH [nTPM]":"11.4","Cell RNA - RH-30 [nTPM]":"3.3","Cell RNA - RPMI-8226 [nTPM]":"6.1","Cell RNA - RPTEC TERT1 [nTPM]":"11.0","Cell RNA - RT4 [nTPM]":"2.4","Cell RNA - SCLC-21H [nTPM]":"9.3","Cell RNA - SH-SY5Y [nTPM]":"13.8","Cell RNA - SiHa [nTPM]":"5.5","Cell RNA - SK-BR-3 [nTPM]":"2.5","Cell RNA - SK-MEL-30 [nTPM]":"14.1","Cell RNA - SuSa [nTPM]":"9.6","Cell RNA - T-47d [nTPM]":"3.5","Cell RNA - THP-1 [nTPM]":"30.3","Cell RNA - TIME [nTPM]":"10.4","Cell RNA - U-138 MG [nTPM]":"8.3","Cell RNA - U-2 OS [nTPM]":"3.9","Cell RNA - U-2197 [nTPM]":"13.3","Cell RNA - U-251 MG [nTPM]":"15.4","Cell RNA - U-266\/70 [nTPM]":"10.4","Cell RNA - U-266\/84 [nTPM]":"6.1","Cell RNA - U-698 [nTPM]":"6.9","Cell RNA - U-87 MG [nTPM]":"11.7","Cell RNA - U-937 [nTPM]":"15.7","Cell RNA - WM-115 [nTPM]":"15.3","Blood RNA - basophil [nTPM]":"1.7","Blood RNA - classical monocyte [nTPM]":"2.1","Blood RNA - eosinophil [nTPM]":"1.2","Blood RNA - gdT-cell [nTPM]":"3.3","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"2.9","Blood RNA - memory B-cell [nTPM]":"2.2","Blood RNA - memory CD4 T-cell [nTPM]":"2.1","Blood RNA - memory CD8 T-cell [nTPM]":"2.5","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"2.8","Blood RNA - naive CD4 T-cell [nTPM]":"3.5","Blood RNA - naive CD8 T-cell [nTPM]":"2.6","Blood RNA - neutrophil [nTPM]":"2.4","Blood RNA - NK-cell [nTPM]":"2.2","Blood RNA - non-classical monocyte [nTPM]":"1.9","Blood RNA - plasmacytoid DC [nTPM]":"3.3","Blood RNA - T-reg [nTPM]":"2.9","Blood RNA - total PBMC [nTPM]":"3.3","Brain RNA - amygdala [nTPM]":"28.5","Brain RNA - basal ganglia [nTPM]":"27.3","Brain RNA - cerebellum [nTPM]":"30.8","Brain RNA - cerebral cortex [nTPM]":"32.5","Brain RNA - hippocampal formation [nTPM]":"27.2","Brain RNA - hypothalamus [nTPM]":"29.4","Brain RNA - medulla oblongata [nTPM]":"27.9","Brain RNA - midbrain [nTPM]":"29.0","Brain RNA - pons [nTPM]":"29.2","Brain RNA - spinal cord [nTPM]":"23.2","Brain RNA - thalamus [nTPM]":"30.8","Brain RNA - white matter [nTPM]":"28.1","Single Cell Type RNA - Adipocytes [nTPM]":"6.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.3","Single Cell Type RNA - Astrocytes [nTPM]":"59.7","Single Cell Type RNA - B-cells [nTPM]":"6.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"9.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"34.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"3.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.1","Single Cell Type RNA - dendritic cells [nTPM]":"2.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.6","Single Cell Type RNA - Early spermatids [nTPM]":"19.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.6","Single Cell Type RNA - Endothelial cells [nTPM]":"7.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"8.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"94.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.6","Single Cell Type RNA - Fibroblasts [nTPM]":"9.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.8","Single Cell Type RNA - granulocytes [nTPM]":"24.1","Single Cell Type RNA - Granulosa cells [nTPM]":"52.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.6","Single Cell Type RNA - Hepatocytes [nTPM]":"8.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.1","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"120.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.4","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"2.2","Single Cell Type RNA - Langerhans cells [nTPM]":"3.1","Single Cell Type RNA - Late spermatids [nTPM]":"14.5","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"4.5","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"57.1","Single Cell Type RNA - monocytes [nTPM]":"3.6","Single Cell Type RNA - Muller glia cells [nTPM]":"6.1","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"66.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"66.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.2","Single Cell Type RNA - Peritubular cells [nTPM]":"11.7","Single Cell Type RNA - Plasma cells [nTPM]":"4.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.8","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.8","Single Cell Type RNA - Spermatocytes [nTPM]":"8.5","Single Cell Type RNA - Spermatogonia [nTPM]":"5.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"6.0","Single Cell Type RNA - Theca cells [nTPM]":"15.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.7","Single Cell Type RNA - Urothelial cells [nTPM]":"10.0"},{"Gene":"ST3GAL5","Gene synonym":["SIAT9","SIATGM3S","ST3GalV"],"Ensembl":"ENSG00000115525","Gene description":"ST3 beta-galactoside alpha-2,3-sialyltransferase 5","Uniprot":["Q9UNP4"],"Chromosome":"2","Position":"85837120-85905199","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"47.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"112.8","Oligodendrocyte precursor cells":"94.0","Oligodendrocytes":"108.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"41.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AN3-CA":"54.4","RT4":"47.0","SK-MEL-30":"40.8","U-266\/84":"42.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034708","HPA040425","HPA068928"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 65: Plasmacytoid DCs - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA034708":"AB_10601594","HPA040425":"AB_2676978","HPA068928":"AB_2686060"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.25e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.99e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.48e-4"},"Tissue RNA - adipose tissue [nTPM]":"17.5","Tissue RNA - adrenal gland [nTPM]":"47.4","Tissue RNA - amygdala [nTPM]":"17.1","Tissue RNA - appendix [nTPM]":"4.6","Tissue RNA - basal ganglia [nTPM]":"26.9","Tissue RNA - bone marrow [nTPM]":"2.3","Tissue RNA - breast [nTPM]":"8.5","Tissue RNA - cerebellum [nTPM]":"16.4","Tissue RNA - cerebral cortex [nTPM]":"20.1","Tissue RNA - cervix [nTPM]":"5.4","Tissue RNA - choroid plexus [nTPM]":"7.9","Tissue RNA - colon [nTPM]":"5.0","Tissue RNA - duodenum [nTPM]":"1.0","Tissue RNA - endometrium 1 [nTPM]":"9.9","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"2.7","Tissue RNA - fallopian tube [nTPM]":"10.4","Tissue RNA - gallbladder [nTPM]":"8.1","Tissue RNA - heart muscle [nTPM]":"4.2","Tissue RNA - hippocampal formation [nTPM]":"16.0","Tissue RNA - hypothalamus [nTPM]":"24.7","Tissue RNA - kidney [nTPM]":"2.8","Tissue RNA - liver [nTPM]":"9.8","Tissue RNA - lung [nTPM]":"14.6","Tissue RNA - lymph node [nTPM]":"9.1","Tissue RNA - medulla oblongata [nTPM]":"24.7","Tissue RNA - midbrain [nTPM]":"22.6","Tissue RNA - ovary [nTPM]":"10.1","Tissue RNA - pancreas [nTPM]":"3.9","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"12.8","Tissue RNA - placenta [nTPM]":"17.7","Tissue RNA - pons [nTPM]":"23.1","Tissue RNA - prostate [nTPM]":"6.7","Tissue RNA - rectum [nTPM]":"2.6","Tissue RNA - retina [nTPM]":"31.0","Tissue RNA - salivary gland [nTPM]":"7.1","Tissue RNA - seminal vesicle [nTPM]":"0.5","Tissue RNA - skeletal muscle [nTPM]":"12.4","Tissue RNA - skin 1 [nTPM]":"6.1","Tissue RNA - small intestine [nTPM]":"6.9","Tissue RNA - smooth muscle [nTPM]":"3.5","Tissue RNA - spinal cord [nTPM]":"20.6","Tissue RNA - spleen [nTPM]":"20.0","Tissue RNA - stomach 1 [nTPM]":"5.6","Tissue RNA - testis [nTPM]":"10.8","Tissue RNA - thalamus [nTPM]":"23.6","Tissue RNA - thymus [nTPM]":"5.0","Tissue RNA - thyroid gland [nTPM]":"27.9","Tissue RNA - tongue [nTPM]":"3.5","Tissue RNA - tonsil [nTPM]":"4.4","Tissue RNA - urinary bladder [nTPM]":"20.8","Tissue RNA - vagina [nTPM]":"5.9","Tissue RNA - white matter [nTPM]":"41.6","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"27.0","Cell RNA - AF22 [nTPM]":"2.5","Cell RNA - AN3-CA [nTPM]":"54.4","Cell RNA - ASC diff [nTPM]":"22.0","Cell RNA - ASC TERT1 [nTPM]":"11.8","Cell RNA - BEWO [nTPM]":"8.0","Cell RNA - BJ [nTPM]":"5.9","Cell RNA - BJ hTERT+ [nTPM]":"18.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.0","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"19.6","Cell RNA - Daudi [nTPM]":"0.7","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"10.2","Cell RNA - GAMG [nTPM]":"2.5","Cell RNA - HaCaT [nTPM]":"1.0","Cell RNA - HAP1 [nTPM]":"3.6","Cell RNA - HBEC3-KT [nTPM]":"6.4","Cell RNA - HBF TERT88 [nTPM]":"7.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"3.2","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"1.1","Cell RNA - Hep G2 [nTPM]":"1.0","Cell RNA - HHSteC [nTPM]":"17.6","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"7.8","Cell RNA - HSkMC [nTPM]":"6.9","Cell RNA - hTCEpi [nTPM]":"0.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.1","Cell RNA - hTERT-HME1 [nTPM]":"0.8","Cell RNA - hTERT-RPE1 [nTPM]":"10.1","Cell RNA - HUVEC TERT2 [nTPM]":"13.7","Cell RNA - JURKAT [nTPM]":"7.4","Cell RNA - K-562 [nTPM]":"0.8","Cell RNA - Karpas-707 [nTPM]":"30.2","Cell RNA - LHCN-M2 [nTPM]":"18.3","Cell RNA - MCF7 [nTPM]":"1.8","Cell RNA - MOLT-4 [nTPM]":"1.9","Cell RNA - NB-4 [nTPM]":"3.1","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"9.6","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"3.5","Cell RNA - RH-30 [nTPM]":"17.0","Cell RNA - RPMI-8226 [nTPM]":"11.0","Cell RNA - RPTEC TERT1 [nTPM]":"2.9","Cell RNA - RT4 [nTPM]":"47.0","Cell RNA - SCLC-21H [nTPM]":"3.8","Cell RNA - SH-SY5Y [nTPM]":"3.8","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"40.8","Cell RNA - SuSa [nTPM]":"5.4","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"1.1","Cell RNA - TIME [nTPM]":"4.5","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"2.7","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"30.0","Cell RNA - U-266\/84 [nTPM]":"42.5","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"4.2","Cell RNA - U-937 [nTPM]":"5.6","Cell RNA - WM-115 [nTPM]":"27.7","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"0.8","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"3.0","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"1.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"2.4","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"17.1","Brain RNA - basal ganglia [nTPM]":"26.9","Brain RNA - cerebellum [nTPM]":"16.4","Brain RNA - cerebral cortex [nTPM]":"20.1","Brain RNA - hippocampal formation [nTPM]":"16.0","Brain RNA - hypothalamus [nTPM]":"24.7","Brain RNA - medulla oblongata [nTPM]":"24.7","Brain RNA - midbrain [nTPM]":"22.6","Brain RNA - pons [nTPM]":"23.1","Brain RNA - spinal cord [nTPM]":"20.6","Brain RNA - thalamus [nTPM]":"23.6","Brain RNA - white matter [nTPM]":"41.6","Single Cell Type RNA - Adipocytes [nTPM]":"8.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"86.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"112.8","Single Cell Type RNA - Astrocytes [nTPM]":"37.5","Single Cell Type RNA - B-cells [nTPM]":"29.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"20.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"56.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"40.0","Single Cell Type RNA - Club cells [nTPM]":"33.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"58.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"48.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"12.0","Single Cell Type RNA - Early spermatids [nTPM]":"12.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"27.8","Single Cell Type RNA - Endothelial cells [nTPM]":"8.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"46.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.1","Single Cell Type RNA - Fibroblasts [nTPM]":"21.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.5","Single Cell Type RNA - granulocytes [nTPM]":"34.8","Single Cell Type RNA - Granulosa cells [nTPM]":"35.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"29.6","Single Cell Type RNA - Hepatocytes [nTPM]":"21.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"35.6","Single Cell Type RNA - Horizontal cells [nTPM]":"72.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"60.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"45.4","Single Cell Type RNA - Langerhans cells [nTPM]":"18.1","Single Cell Type RNA - Late spermatids [nTPM]":"12.0","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"24.9","Single Cell Type RNA - Melanocytes [nTPM]":"32.0","Single Cell Type RNA - Microglial cells [nTPM]":"45.9","Single Cell Type RNA - monocytes [nTPM]":"20.1","Single Cell Type RNA - Muller glia cells [nTPM]":"56.0","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"94.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"108.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"19.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"45.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.0","Single Cell Type RNA - Spermatocytes [nTPM]":"8.4","Single Cell Type RNA - Spermatogonia [nTPM]":"16.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"28.9","Single Cell Type RNA - Theca cells [nTPM]":"6.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"8.3"},{"Gene":"STAMBP","Gene synonym":["AMSH"],"Ensembl":"ENSG00000124356","Gene description":"STAM binding protein","Uniprot":["O95630"],"Chromosome":"2","Position":"73828916-73873659","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"12","RNA cell line specific nTPM":{"LHCN-M2":"1108.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035800","HPA035801"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"18000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Plasma membrane","Cytosol"],"Antibody RRID":{"HPA035800":"AB_10670591","HPA035801":"AB_2732470"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.70e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.79e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Tissue RNA - adipose tissue [nTPM]":"15.6","Tissue RNA - adrenal gland [nTPM]":"11.6","Tissue RNA - amygdala [nTPM]":"21.7","Tissue RNA - appendix [nTPM]":"14.6","Tissue RNA - basal ganglia [nTPM]":"30.6","Tissue RNA - bone marrow [nTPM]":"13.3","Tissue RNA - breast [nTPM]":"20.2","Tissue RNA - cerebellum [nTPM]":"29.7","Tissue RNA - cerebral cortex [nTPM]":"23.8","Tissue RNA - cervix [nTPM]":"19.3","Tissue RNA - choroid plexus [nTPM]":"19.3","Tissue RNA - colon [nTPM]":"21.5","Tissue RNA - duodenum [nTPM]":"20.7","Tissue RNA - endometrium 1 [nTPM]":"20.6","Tissue RNA - epididymis [nTPM]":"15.5","Tissue RNA - esophagus [nTPM]":"25.4","Tissue RNA - fallopian tube [nTPM]":"18.3","Tissue RNA - gallbladder [nTPM]":"16.9","Tissue RNA - heart muscle [nTPM]":"22.3","Tissue RNA - hippocampal formation [nTPM]":"20.6","Tissue RNA - hypothalamus [nTPM]":"24.5","Tissue RNA - kidney [nTPM]":"21.9","Tissue RNA - liver [nTPM]":"19.0","Tissue RNA - lung [nTPM]":"15.7","Tissue RNA - lymph node [nTPM]":"19.3","Tissue RNA - medulla oblongata [nTPM]":"31.3","Tissue RNA - midbrain [nTPM]":"28.0","Tissue RNA - ovary [nTPM]":"17.7","Tissue RNA - pancreas [nTPM]":"12.2","Tissue RNA - parathyroid gland [nTPM]":"24.3","Tissue RNA - pituitary gland [nTPM]":"9.3","Tissue RNA - placenta [nTPM]":"17.3","Tissue RNA - pons [nTPM]":"30.4","Tissue RNA - prostate [nTPM]":"22.1","Tissue RNA - rectum [nTPM]":"23.2","Tissue RNA - retina [nTPM]":"14.6","Tissue RNA - salivary gland [nTPM]":"21.5","Tissue RNA - seminal vesicle [nTPM]":"15.6","Tissue RNA - skeletal muscle [nTPM]":"37.4","Tissue RNA - skin 1 [nTPM]":"16.7","Tissue RNA - small intestine [nTPM]":"20.4","Tissue RNA - smooth muscle [nTPM]":"21.3","Tissue RNA - spinal cord [nTPM]":"27.9","Tissue RNA - spleen [nTPM]":"14.9","Tissue RNA - stomach 1 [nTPM]":"18.2","Tissue RNA - testis [nTPM]":"15.8","Tissue RNA - thalamus [nTPM]":"27.1","Tissue RNA - thymus [nTPM]":"23.2","Tissue RNA - thyroid gland [nTPM]":"22.6","Tissue RNA - tongue [nTPM]":"42.8","Tissue RNA - tonsil [nTPM]":"21.6","Tissue RNA - urinary bladder [nTPM]":"16.8","Tissue RNA - vagina [nTPM]":"16.0","Tissue RNA - white matter [nTPM]":"38.6","Cell RNA - A-431 [nTPM]":"39.0","Cell RNA - A549 [nTPM]":"44.0","Cell RNA - AF22 [nTPM]":"34.0","Cell RNA - AN3-CA [nTPM]":"31.6","Cell RNA - ASC diff [nTPM]":"31.1","Cell RNA - ASC TERT1 [nTPM]":"37.2","Cell RNA - BEWO [nTPM]":"39.1","Cell RNA - BJ [nTPM]":"23.3","Cell RNA - BJ hTERT+ [nTPM]":"31.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"42.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"40.3","Cell RNA - CACO-2 [nTPM]":"73.7","Cell RNA - CAPAN-2 [nTPM]":"35.9","Cell RNA - Daudi [nTPM]":"32.2","Cell RNA - EFO-21 [nTPM]":"35.8","Cell RNA - fHDF\/TERT166 [nTPM]":"19.8","Cell RNA - GAMG [nTPM]":"55.7","Cell RNA - HaCaT [nTPM]":"30.0","Cell RNA - HAP1 [nTPM]":"36.6","Cell RNA - HBEC3-KT [nTPM]":"81.7","Cell RNA - HBF TERT88 [nTPM]":"47.6","Cell RNA - HDLM-2 [nTPM]":"56.6","Cell RNA - HEK 293 [nTPM]":"41.3","Cell RNA - HEL [nTPM]":"43.3","Cell RNA - HeLa [nTPM]":"29.1","Cell RNA - Hep G2 [nTPM]":"58.1","Cell RNA - HHSteC [nTPM]":"43.4","Cell RNA - HL-60 [nTPM]":"35.8","Cell RNA - HMC-1 [nTPM]":"50.0","Cell RNA - HSkMC [nTPM]":"30.1","Cell RNA - hTCEpi [nTPM]":"57.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"49.6","Cell RNA - hTERT-HME1 [nTPM]":"70.7","Cell RNA - hTERT-RPE1 [nTPM]":"53.5","Cell RNA - HUVEC TERT2 [nTPM]":"25.1","Cell RNA - JURKAT [nTPM]":"43.7","Cell RNA - K-562 [nTPM]":"47.9","Cell RNA - Karpas-707 [nTPM]":"47.8","Cell RNA - LHCN-M2 [nTPM]":"1108.9","Cell RNA - MCF7 [nTPM]":"46.8","Cell RNA - MOLT-4 [nTPM]":"55.9","Cell RNA - NB-4 [nTPM]":"32.4","Cell RNA - NTERA-2 [nTPM]":"54.9","Cell RNA - OE19 [nTPM]":"55.1","Cell RNA - PC-3 [nTPM]":"22.7","Cell RNA - REH [nTPM]":"38.6","Cell RNA - RH-30 [nTPM]":"89.4","Cell RNA - RPMI-8226 [nTPM]":"46.1","Cell RNA - RPTEC TERT1 [nTPM]":"45.2","Cell RNA - RT4 [nTPM]":"43.0","Cell RNA - SCLC-21H [nTPM]":"62.0","Cell RNA - SH-SY5Y [nTPM]":"45.8","Cell RNA - SiHa [nTPM]":"28.4","Cell RNA - SK-BR-3 [nTPM]":"34.6","Cell RNA - SK-MEL-30 [nTPM]":"49.1","Cell RNA - SuSa [nTPM]":"36.4","Cell RNA - T-47d [nTPM]":"32.3","Cell RNA - THP-1 [nTPM]":"21.4","Cell RNA - TIME [nTPM]":"22.0","Cell RNA - U-138 MG [nTPM]":"37.5","Cell RNA - U-2 OS [nTPM]":"44.5","Cell RNA - U-2197 [nTPM]":"22.9","Cell RNA - U-251 MG [nTPM]":"41.9","Cell RNA - U-266\/70 [nTPM]":"44.8","Cell RNA - U-266\/84 [nTPM]":"46.9","Cell RNA - U-698 [nTPM]":"24.9","Cell RNA - U-87 MG [nTPM]":"46.4","Cell RNA - U-937 [nTPM]":"38.1","Cell RNA - WM-115 [nTPM]":"44.7","Blood RNA - basophil [nTPM]":"30.7","Blood RNA - classical monocyte [nTPM]":"18.9","Blood RNA - eosinophil [nTPM]":"34.2","Blood RNA - gdT-cell [nTPM]":"15.9","Blood RNA - intermediate monocyte [nTPM]":"21.4","Blood RNA - MAIT T-cell [nTPM]":"17.2","Blood RNA - memory B-cell [nTPM]":"21.5","Blood RNA - memory CD4 T-cell [nTPM]":"18.3","Blood RNA - memory CD8 T-cell [nTPM]":"15.6","Blood RNA - myeloid DC [nTPM]":"19.9","Blood RNA - naive B-cell [nTPM]":"19.3","Blood RNA - naive CD4 T-cell [nTPM]":"18.9","Blood RNA - naive CD8 T-cell [nTPM]":"14.4","Blood RNA - neutrophil [nTPM]":"27.6","Blood RNA - NK-cell [nTPM]":"22.3","Blood RNA - non-classical monocyte [nTPM]":"19.9","Blood RNA - plasmacytoid DC [nTPM]":"19.5","Blood RNA - T-reg [nTPM]":"25.8","Blood RNA - total PBMC [nTPM]":"14.9","Brain RNA - amygdala [nTPM]":"21.7","Brain RNA - basal ganglia [nTPM]":"30.6","Brain RNA - cerebellum [nTPM]":"29.7","Brain RNA - cerebral cortex [nTPM]":"23.8","Brain RNA - hippocampal formation [nTPM]":"20.6","Brain RNA - hypothalamus [nTPM]":"24.5","Brain RNA - medulla oblongata [nTPM]":"31.3","Brain RNA - midbrain [nTPM]":"28.0","Brain RNA - pons [nTPM]":"30.4","Brain RNA - spinal cord [nTPM]":"27.9","Brain RNA - thalamus [nTPM]":"27.1","Brain RNA - white matter [nTPM]":"38.6","Single Cell Type RNA - Adipocytes [nTPM]":"22.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.7","Single Cell Type RNA - Astrocytes [nTPM]":"22.9","Single Cell Type RNA - B-cells [nTPM]":"21.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"28.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"61.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.3","Single Cell Type RNA - Bipolar cells [nTPM]":"22.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"28.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"27.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"41.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"28.6","Single Cell Type RNA - Club cells [nTPM]":"34.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"43.0","Single Cell Type RNA - dendritic cells [nTPM]":"27.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"48.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"49.0","Single Cell Type RNA - Ductal cells [nTPM]":"37.9","Single Cell Type RNA - Early spermatids [nTPM]":"80.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"35.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"37.3","Single Cell Type RNA - Endothelial cells [nTPM]":"21.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.3","Single Cell Type RNA - Erythroid cells [nTPM]":"34.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"36.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"32.5","Single Cell Type RNA - Fibroblasts [nTPM]":"26.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"45.8","Single Cell Type RNA - granulocytes [nTPM]":"52.6","Single Cell Type RNA - Granulosa cells [nTPM]":"21.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.5","Single Cell Type RNA - Hepatocytes [nTPM]":"41.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"33.0","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"36.4","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"27.7","Single Cell Type RNA - Langerhans cells [nTPM]":"16.2","Single Cell Type RNA - Late spermatids [nTPM]":"125.0","Single Cell Type RNA - Leydig cells [nTPM]":"32.6","Single Cell Type RNA - Macrophages [nTPM]":"25.2","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"34.1","Single Cell Type RNA - Muller glia cells [nTPM]":"24.9","Single Cell Type RNA - NK-cells [nTPM]":"25.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"26.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"67.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"44.5","Single Cell Type RNA - Paneth cells [nTPM]":"41.8","Single Cell Type RNA - Peritubular cells [nTPM]":"34.6","Single Cell Type RNA - Plasma cells [nTPM]":"21.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"40.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"57.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"68.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"24.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.0","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"28.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.2","Single Cell Type RNA - Spermatocytes [nTPM]":"33.1","Single Cell Type RNA - Spermatogonia [nTPM]":"44.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"44.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"44.5","Single Cell Type RNA - T-cells [nTPM]":"21.4","Single Cell Type RNA - Theca cells [nTPM]":"27.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"34.3","Single Cell Type RNA - Urothelial cells [nTPM]":"27.1"},{"Gene":"STEAP3","Gene synonym":["dudlin-2","STMP3","TSAP6"],"Ensembl":"ENSG00000115107","Gene description":"STEAP3 metalloreductase","Uniprot":["Q658P3"],"Chromosome":"2","Position":"119223831-119265652","Protein class":["Disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Cell cycle","Ion transport","Iron transport","Transport"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"189.5","parathyroid gland":"78.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"33.3","Exocrine glandular cells":"36.2","Hepatocytes":"91.6","Respiratory ciliated cells":"36.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"2.4","intermediate monocyte":"2.7","myeloid DC":"4.1","NK-cell":"1.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"4.1","monocytes":"2.7","NK-cells":"1.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-87 MG":"149.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050510"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA050510":"AB_2681151"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.1","Tissue RNA - adrenal gland [nTPM]":"6.3","Tissue RNA - amygdala [nTPM]":"4.3","Tissue RNA - appendix [nTPM]":"3.9","Tissue RNA - basal ganglia [nTPM]":"3.7","Tissue RNA - bone marrow [nTPM]":"16.9","Tissue RNA - breast [nTPM]":"14.5","Tissue RNA - cerebellum [nTPM]":"7.1","Tissue RNA - cerebral cortex [nTPM]":"4.6","Tissue RNA - cervix [nTPM]":"16.7","Tissue RNA - choroid plexus [nTPM]":"10.6","Tissue RNA - colon [nTPM]":"9.5","Tissue RNA - duodenum [nTPM]":"22.1","Tissue RNA - endometrium 1 [nTPM]":"3.6","Tissue RNA - epididymis [nTPM]":"5.3","Tissue RNA - esophagus [nTPM]":"15.8","Tissue RNA - fallopian tube [nTPM]":"7.7","Tissue RNA - gallbladder [nTPM]":"2.3","Tissue RNA - heart muscle [nTPM]":"9.5","Tissue RNA - hippocampal formation [nTPM]":"7.0","Tissue RNA - hypothalamus [nTPM]":"7.5","Tissue RNA - kidney [nTPM]":"6.9","Tissue RNA - liver [nTPM]":"189.5","Tissue RNA - lung [nTPM]":"9.1","Tissue RNA - lymph node [nTPM]":"0.9","Tissue RNA - medulla oblongata [nTPM]":"14.4","Tissue RNA - midbrain [nTPM]":"9.4","Tissue RNA - ovary [nTPM]":"4.4","Tissue RNA - pancreas [nTPM]":"27.1","Tissue RNA - parathyroid gland [nTPM]":"78.9","Tissue RNA - pituitary gland [nTPM]":"13.8","Tissue RNA - placenta [nTPM]":"11.3","Tissue RNA - pons [nTPM]":"12.8","Tissue RNA - prostate [nTPM]":"11.8","Tissue RNA - rectum [nTPM]":"6.9","Tissue RNA - retina [nTPM]":"0.7","Tissue RNA - salivary gland [nTPM]":"34.3","Tissue RNA - seminal vesicle [nTPM]":"7.5","Tissue RNA - skeletal muscle [nTPM]":"29.9","Tissue RNA - skin 1 [nTPM]":"9.0","Tissue RNA - small intestine [nTPM]":"10.9","Tissue RNA - smooth muscle [nTPM]":"3.1","Tissue RNA - spinal cord [nTPM]":"7.6","Tissue RNA - spleen [nTPM]":"1.8","Tissue RNA - stomach 1 [nTPM]":"22.5","Tissue RNA - testis [nTPM]":"1.9","Tissue RNA - thalamus [nTPM]":"7.2","Tissue RNA - thymus [nTPM]":"2.2","Tissue RNA - thyroid gland [nTPM]":"5.4","Tissue RNA - tongue [nTPM]":"12.5","Tissue RNA - tonsil [nTPM]":"3.1","Tissue RNA - urinary bladder [nTPM]":"7.0","Tissue RNA - vagina [nTPM]":"7.2","Tissue RNA - white matter [nTPM]":"12.7","Cell RNA - A-431 [nTPM]":"21.8","Cell RNA - A549 [nTPM]":"25.6","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"8.7","Cell RNA - ASC diff [nTPM]":"12.1","Cell RNA - ASC TERT1 [nTPM]":"112.9","Cell RNA - BEWO [nTPM]":"22.1","Cell RNA - BJ [nTPM]":"6.8","Cell RNA - BJ hTERT+ [nTPM]":"7.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.8","Cell RNA - CACO-2 [nTPM]":"19.5","Cell RNA - CAPAN-2 [nTPM]":"29.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"49.9","Cell RNA - fHDF\/TERT166 [nTPM]":"38.5","Cell RNA - GAMG [nTPM]":"94.1","Cell RNA - HaCaT [nTPM]":"35.9","Cell RNA - HAP1 [nTPM]":"11.1","Cell RNA - HBEC3-KT [nTPM]":"22.4","Cell RNA - HBF TERT88 [nTPM]":"14.9","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"35.9","Cell RNA - HEL [nTPM]":"42.1","Cell RNA - HeLa [nTPM]":"22.2","Cell RNA - Hep G2 [nTPM]":"38.8","Cell RNA - HHSteC [nTPM]":"30.0","Cell RNA - HL-60 [nTPM]":"10.5","Cell RNA - HMC-1 [nTPM]":"7.7","Cell RNA - HSkMC [nTPM]":"67.3","Cell RNA - hTCEpi [nTPM]":"38.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"78.0","Cell RNA - hTERT-HME1 [nTPM]":"27.7","Cell RNA - hTERT-RPE1 [nTPM]":"89.8","Cell RNA - HUVEC TERT2 [nTPM]":"11.4","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"20.9","Cell RNA - Karpas-707 [nTPM]":"4.2","Cell RNA - LHCN-M2 [nTPM]":"37.6","Cell RNA - MCF7 [nTPM]":"20.6","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"6.2","Cell RNA - NTERA-2 [nTPM]":"34.2","Cell RNA - OE19 [nTPM]":"33.3","Cell RNA - PC-3 [nTPM]":"52.7","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"14.7","Cell RNA - RPMI-8226 [nTPM]":"18.5","Cell RNA - RPTEC TERT1 [nTPM]":"16.2","Cell RNA - RT4 [nTPM]":"54.1","Cell RNA - SCLC-21H [nTPM]":"41.9","Cell RNA - SH-SY5Y [nTPM]":"7.7","Cell RNA - SiHa [nTPM]":"18.8","Cell RNA - SK-BR-3 [nTPM]":"64.1","Cell RNA - SK-MEL-30 [nTPM]":"4.9","Cell RNA - SuSa [nTPM]":"4.9","Cell RNA - T-47d [nTPM]":"12.7","Cell RNA - THP-1 [nTPM]":"13.7","Cell RNA - TIME [nTPM]":"49.6","Cell RNA - U-138 MG [nTPM]":"81.2","Cell RNA - U-2 OS [nTPM]":"46.8","Cell RNA - U-2197 [nTPM]":"17.4","Cell RNA - U-251 MG [nTPM]":"37.4","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"149.1","Cell RNA - U-937 [nTPM]":"26.2","Cell RNA - WM-115 [nTPM]":"17.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.4","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"2.7","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"4.1","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.3","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"4.3","Brain RNA - basal ganglia [nTPM]":"3.7","Brain RNA - cerebellum [nTPM]":"7.1","Brain RNA - cerebral cortex [nTPM]":"4.6","Brain RNA - hippocampal formation [nTPM]":"7.0","Brain RNA - hypothalamus [nTPM]":"7.5","Brain RNA - medulla oblongata [nTPM]":"14.4","Brain RNA - midbrain [nTPM]":"9.4","Brain RNA - pons [nTPM]":"12.8","Brain RNA - spinal cord [nTPM]":"7.6","Brain RNA - thalamus [nTPM]":"7.2","Brain RNA - white matter [nTPM]":"12.7","Single Cell Type RNA - Adipocytes [nTPM]":"9.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.9","Single Cell Type RNA - Astrocytes [nTPM]":"2.3","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"16.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"33.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"8.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.9","Single Cell Type RNA - Endothelial cells [nTPM]":"6.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"29.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"36.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.1","Single Cell Type RNA - Fibroblasts [nTPM]":"3.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.7","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"3.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"91.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.0","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.9","Single Cell Type RNA - Langerhans cells [nTPM]":"3.8","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"6.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"1.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.8","Single Cell Type RNA - Paneth cells [nTPM]":"7.7","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"36.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.7","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"13.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.6","Single Cell Type RNA - Urothelial cells [nTPM]":"8.9"},{"Gene":"STIM1","Gene synonym":["D11S4896E","GOK"],"Ensembl":"ENSG00000167323","Gene description":"Stromal interaction molecule 1","Uniprot":["Q13586"],"Chromosome":"11","Position":"3854527-4093210","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"77.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011088","HPA012123","CAB037128","CAB037288"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1900000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB037128":"AB_1079007","CAB037288":"AB_1079008","HPA011088":"AB_1849884","HPA012123":"AB_1849882"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.75e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Tissue RNA - adipose tissue [nTPM]":"40.6","Tissue RNA - adrenal gland [nTPM]":"18.4","Tissue RNA - amygdala [nTPM]":"32.9","Tissue RNA - appendix [nTPM]":"22.3","Tissue RNA - basal ganglia [nTPM]":"31.5","Tissue RNA - bone marrow [nTPM]":"46.4","Tissue RNA - breast [nTPM]":"33.1","Tissue RNA - cerebellum [nTPM]":"18.1","Tissue RNA - cerebral cortex [nTPM]":"34.5","Tissue RNA - cervix [nTPM]":"40.4","Tissue RNA - choroid plexus [nTPM]":"30.5","Tissue RNA - colon [nTPM]":"33.7","Tissue RNA - duodenum [nTPM]":"18.1","Tissue RNA - endometrium 1 [nTPM]":"39.3","Tissue RNA - epididymis [nTPM]":"18.2","Tissue RNA - esophagus [nTPM]":"65.6","Tissue RNA - fallopian tube [nTPM]":"39.0","Tissue RNA - gallbladder [nTPM]":"25.1","Tissue RNA - heart muscle [nTPM]":"24.0","Tissue RNA - hippocampal formation [nTPM]":"30.5","Tissue RNA - hypothalamus [nTPM]":"23.1","Tissue RNA - kidney [nTPM]":"20.0","Tissue RNA - liver [nTPM]":"38.0","Tissue RNA - lung [nTPM]":"26.8","Tissue RNA - lymph node [nTPM]":"29.8","Tissue RNA - medulla oblongata [nTPM]":"17.4","Tissue RNA - midbrain [nTPM]":"22.9","Tissue RNA - ovary [nTPM]":"41.2","Tissue RNA - pancreas [nTPM]":"30.1","Tissue RNA - parathyroid gland [nTPM]":"43.7","Tissue RNA - pituitary gland [nTPM]":"18.0","Tissue RNA - placenta [nTPM]":"17.5","Tissue RNA - pons [nTPM]":"18.9","Tissue RNA - prostate [nTPM]":"26.0","Tissue RNA - rectum [nTPM]":"24.6","Tissue RNA - retina [nTPM]":"11.4","Tissue RNA - salivary gland [nTPM]":"61.1","Tissue RNA - seminal vesicle [nTPM]":"24.3","Tissue RNA - skeletal muscle [nTPM]":"111.9","Tissue RNA - skin 1 [nTPM]":"47.1","Tissue RNA - small intestine [nTPM]":"31.3","Tissue RNA - smooth muscle [nTPM]":"34.3","Tissue RNA - spinal cord [nTPM]":"18.6","Tissue RNA - spleen [nTPM]":"31.5","Tissue RNA - stomach 1 [nTPM]":"32.2","Tissue RNA - testis [nTPM]":"25.4","Tissue RNA - thalamus [nTPM]":"26.9","Tissue RNA - thymus [nTPM]":"68.6","Tissue RNA - thyroid gland [nTPM]":"40.9","Tissue RNA - tongue [nTPM]":"49.7","Tissue RNA - tonsil [nTPM]":"29.7","Tissue RNA - urinary bladder [nTPM]":"32.2","Tissue RNA - vagina [nTPM]":"40.4","Tissue RNA - white matter [nTPM]":"22.4","Cell RNA - A-431 [nTPM]":"42.4","Cell RNA - A549 [nTPM]":"48.5","Cell RNA - AF22 [nTPM]":"14.1","Cell RNA - AN3-CA [nTPM]":"23.5","Cell RNA - ASC diff [nTPM]":"60.9","Cell RNA - ASC TERT1 [nTPM]":"55.4","Cell RNA - BEWO [nTPM]":"22.2","Cell RNA - BJ [nTPM]":"31.1","Cell RNA - BJ hTERT+ [nTPM]":"31.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"22.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"28.5","Cell RNA - CACO-2 [nTPM]":"24.3","Cell RNA - CAPAN-2 [nTPM]":"13.8","Cell RNA - Daudi [nTPM]":"44.7","Cell RNA - EFO-21 [nTPM]":"35.4","Cell RNA - fHDF\/TERT166 [nTPM]":"46.2","Cell RNA - GAMG [nTPM]":"50.9","Cell RNA - HaCaT [nTPM]":"74.3","Cell RNA - HAP1 [nTPM]":"20.1","Cell RNA - HBEC3-KT [nTPM]":"21.5","Cell RNA - HBF TERT88 [nTPM]":"19.3","Cell RNA - HDLM-2 [nTPM]":"36.7","Cell RNA - HEK 293 [nTPM]":"30.5","Cell RNA - HEL [nTPM]":"70.1","Cell RNA - HeLa [nTPM]":"19.2","Cell RNA - Hep G2 [nTPM]":"36.0","Cell RNA - HHSteC [nTPM]":"53.0","Cell RNA - HL-60 [nTPM]":"58.9","Cell RNA - HMC-1 [nTPM]":"40.1","Cell RNA - HSkMC [nTPM]":"56.8","Cell RNA - hTCEpi [nTPM]":"53.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.0","Cell RNA - hTERT-HME1 [nTPM]":"90.7","Cell RNA - hTERT-RPE1 [nTPM]":"28.2","Cell RNA - HUVEC TERT2 [nTPM]":"31.7","Cell RNA - JURKAT [nTPM]":"59.6","Cell RNA - K-562 [nTPM]":"44.2","Cell RNA - Karpas-707 [nTPM]":"80.1","Cell RNA - LHCN-M2 [nTPM]":"24.7","Cell RNA - MCF7 [nTPM]":"9.8","Cell RNA - MOLT-4 [nTPM]":"55.8","Cell RNA - NB-4 [nTPM]":"20.7","Cell RNA - NTERA-2 [nTPM]":"5.4","Cell RNA - OE19 [nTPM]":"23.3","Cell RNA - PC-3 [nTPM]":"18.1","Cell RNA - REH [nTPM]":"13.8","Cell RNA - RH-30 [nTPM]":"22.1","Cell RNA - RPMI-8226 [nTPM]":"41.7","Cell RNA - RPTEC TERT1 [nTPM]":"38.2","Cell RNA - RT4 [nTPM]":"23.7","Cell RNA - SCLC-21H [nTPM]":"3.4","Cell RNA - SH-SY5Y [nTPM]":"14.2","Cell RNA - SiHa [nTPM]":"51.2","Cell RNA - SK-BR-3 [nTPM]":"33.5","Cell RNA - SK-MEL-30 [nTPM]":"19.2","Cell RNA - SuSa [nTPM]":"22.5","Cell RNA - T-47d [nTPM]":"12.7","Cell RNA - THP-1 [nTPM]":"32.4","Cell RNA - TIME [nTPM]":"34.0","Cell RNA - U-138 MG [nTPM]":"40.2","Cell RNA - U-2 OS [nTPM]":"13.8","Cell RNA - U-2197 [nTPM]":"42.2","Cell RNA - U-251 MG [nTPM]":"25.1","Cell RNA - U-266\/70 [nTPM]":"88.0","Cell RNA - U-266\/84 [nTPM]":"71.9","Cell RNA - U-698 [nTPM]":"22.5","Cell RNA - U-87 MG [nTPM]":"33.4","Cell RNA - U-937 [nTPM]":"24.0","Cell RNA - WM-115 [nTPM]":"26.0","Blood RNA - basophil [nTPM]":"16.6","Blood RNA - classical monocyte [nTPM]":"11.2","Blood RNA - eosinophil [nTPM]":"20.0","Blood RNA - gdT-cell [nTPM]":"17.8","Blood RNA - intermediate monocyte [nTPM]":"14.8","Blood RNA - MAIT T-cell [nTPM]":"14.5","Blood RNA - memory B-cell [nTPM]":"7.9","Blood RNA - memory CD4 T-cell [nTPM]":"13.1","Blood RNA - memory CD8 T-cell [nTPM]":"19.5","Blood RNA - myeloid DC [nTPM]":"9.6","Blood RNA - naive B-cell [nTPM]":"11.4","Blood RNA - naive CD4 T-cell [nTPM]":"14.8","Blood RNA - naive CD8 T-cell [nTPM]":"13.3","Blood RNA - neutrophil [nTPM]":"16.7","Blood RNA - NK-cell [nTPM]":"20.8","Blood RNA - non-classical monocyte [nTPM]":"25.5","Blood RNA - plasmacytoid DC [nTPM]":"8.3","Blood RNA - T-reg [nTPM]":"14.7","Blood RNA - total PBMC [nTPM]":"17.1","Brain RNA - amygdala [nTPM]":"32.9","Brain RNA - basal ganglia [nTPM]":"31.5","Brain RNA - cerebellum [nTPM]":"18.1","Brain RNA - cerebral cortex [nTPM]":"34.5","Brain RNA - hippocampal formation [nTPM]":"30.5","Brain RNA - hypothalamus [nTPM]":"23.1","Brain RNA - medulla oblongata [nTPM]":"17.4","Brain RNA - midbrain [nTPM]":"22.9","Brain RNA - pons [nTPM]":"18.9","Brain RNA - spinal cord [nTPM]":"18.6","Brain RNA - thalamus [nTPM]":"26.9","Brain RNA - white matter [nTPM]":"22.4","Single Cell Type RNA - Adipocytes [nTPM]":"20.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.2","Single Cell Type RNA - Astrocytes [nTPM]":"53.8","Single Cell Type RNA - B-cells [nTPM]":"22.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.6","Single Cell Type RNA - Bipolar cells [nTPM]":"5.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"10.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.3","Single Cell Type RNA - dendritic cells [nTPM]":"35.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"27.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"12.4","Single Cell Type RNA - Early spermatids [nTPM]":"4.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"35.5","Single Cell Type RNA - Endothelial cells [nTPM]":"12.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.1","Single Cell Type RNA - Erythroid cells [nTPM]":"18.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"63.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.5","Single Cell Type RNA - Fibroblasts [nTPM]":"20.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.0","Single Cell Type RNA - granulocytes [nTPM]":"29.8","Single Cell Type RNA - Granulosa cells [nTPM]":"4.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.3","Single Cell Type RNA - Hepatocytes [nTPM]":"32.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.7","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"56.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.0","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"22.2","Single Cell Type RNA - Langerhans cells [nTPM]":"15.2","Single Cell Type RNA - Late spermatids [nTPM]":"9.2","Single Cell Type RNA - Leydig cells [nTPM]":"27.4","Single Cell Type RNA - Macrophages [nTPM]":"18.7","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"57.1","Single Cell Type RNA - monocytes [nTPM]":"11.0","Single Cell Type RNA - Muller glia cells [nTPM]":"16.5","Single Cell Type RNA - NK-cells [nTPM]":"36.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"77.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.3","Single Cell Type RNA - Paneth cells [nTPM]":"6.7","Single Cell Type RNA - Peritubular cells [nTPM]":"11.3","Single Cell Type RNA - Plasma cells [nTPM]":"14.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.9","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.4","Single Cell Type RNA - Spermatocytes [nTPM]":"21.4","Single Cell Type RNA - Spermatogonia [nTPM]":"13.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"50.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.4","Single Cell Type RNA - T-cells [nTPM]":"28.5","Single Cell Type RNA - Theca cells [nTPM]":"1.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.8","Single Cell Type RNA - Urothelial cells [nTPM]":"11.9"},{"Gene":"STK10","Gene synonym":["LOK","PRO2729"],"Ensembl":"ENSG00000072786","Gene description":"Serine\/threonine kinase 10","Uniprot":["O94804"],"Chromosome":"5","Position":"172042079-172188224","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"76.5","lymphoid tissue":"45.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"107.7","Kupffer cells":"91.4","NK-cells":"171.0","T-cells":"81.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"WM-115":"143.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015083","CAB020840"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"16000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB020840":null,"HPA015083":"AB_2669151"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.76e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.63e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Tissue RNA - adipose tissue [nTPM]":"14.9","Tissue RNA - adrenal gland [nTPM]":"5.7","Tissue RNA - amygdala [nTPM]":"3.1","Tissue RNA - appendix [nTPM]":"37.1","Tissue RNA - basal ganglia [nTPM]":"3.6","Tissue RNA - bone marrow [nTPM]":"76.5","Tissue RNA - breast [nTPM]":"11.4","Tissue RNA - cerebellum [nTPM]":"18.4","Tissue RNA - cerebral cortex [nTPM]":"5.6","Tissue RNA - cervix [nTPM]":"4.5","Tissue RNA - choroid plexus [nTPM]":"3.5","Tissue RNA - colon [nTPM]":"8.5","Tissue RNA - duodenum [nTPM]":"8.4","Tissue RNA - endometrium 1 [nTPM]":"4.9","Tissue RNA - epididymis [nTPM]":"1.7","Tissue RNA - esophagus [nTPM]":"5.6","Tissue RNA - fallopian tube [nTPM]":"4.7","Tissue RNA - gallbladder [nTPM]":"13.2","Tissue RNA - heart muscle [nTPM]":"7.6","Tissue RNA - hippocampal formation [nTPM]":"3.1","Tissue RNA - hypothalamus [nTPM]":"4.0","Tissue RNA - kidney [nTPM]":"5.9","Tissue RNA - liver [nTPM]":"6.2","Tissue RNA - lung [nTPM]":"18.4","Tissue RNA - lymph node [nTPM]":"44.1","Tissue RNA - medulla oblongata [nTPM]":"6.2","Tissue RNA - midbrain [nTPM]":"4.4","Tissue RNA - ovary [nTPM]":"2.5","Tissue RNA - pancreas [nTPM]":"7.2","Tissue RNA - parathyroid gland [nTPM]":"3.1","Tissue RNA - pituitary gland [nTPM]":"4.1","Tissue RNA - placenta [nTPM]":"17.2","Tissue RNA - pons [nTPM]":"5.8","Tissue RNA - prostate [nTPM]":"4.4","Tissue RNA - rectum [nTPM]":"6.9","Tissue RNA - retina [nTPM]":"1.2","Tissue RNA - salivary gland [nTPM]":"4.7","Tissue RNA - seminal vesicle [nTPM]":"3.5","Tissue RNA - skeletal muscle [nTPM]":"5.0","Tissue RNA - skin 1 [nTPM]":"14.2","Tissue RNA - small intestine [nTPM]":"16.0","Tissue RNA - smooth muscle [nTPM]":"7.8","Tissue RNA - spinal cord [nTPM]":"5.4","Tissue RNA - spleen [nTPM]":"45.2","Tissue RNA - stomach 1 [nTPM]":"11.1","Tissue RNA - testis [nTPM]":"14.0","Tissue RNA - thalamus [nTPM]":"6.4","Tissue RNA - thymus [nTPM]":"20.6","Tissue RNA - thyroid gland [nTPM]":"5.3","Tissue RNA - tongue [nTPM]":"5.5","Tissue RNA - tonsil [nTPM]":"25.0","Tissue RNA - urinary bladder [nTPM]":"14.9","Tissue RNA - vagina [nTPM]":"5.2","Tissue RNA - white matter [nTPM]":"7.0","Cell RNA - A-431 [nTPM]":"22.2","Cell RNA - A549 [nTPM]":"20.2","Cell RNA - AF22 [nTPM]":"12.7","Cell RNA - AN3-CA [nTPM]":"18.8","Cell RNA - ASC diff [nTPM]":"14.7","Cell RNA - ASC TERT1 [nTPM]":"18.1","Cell RNA - BEWO [nTPM]":"31.5","Cell RNA - BJ [nTPM]":"28.4","Cell RNA - BJ hTERT+ [nTPM]":"24.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"18.9","Cell RNA - CACO-2 [nTPM]":"10.6","Cell RNA - CAPAN-2 [nTPM]":"28.6","Cell RNA - Daudi [nTPM]":"26.8","Cell RNA - EFO-21 [nTPM]":"14.6","Cell RNA - fHDF\/TERT166 [nTPM]":"35.6","Cell RNA - GAMG [nTPM]":"42.3","Cell RNA - HaCaT [nTPM]":"25.4","Cell RNA - HAP1 [nTPM]":"5.7","Cell RNA - HBEC3-KT [nTPM]":"35.1","Cell RNA - HBF TERT88 [nTPM]":"13.5","Cell RNA - HDLM-2 [nTPM]":"35.0","Cell RNA - HEK 293 [nTPM]":"9.3","Cell RNA - HEL [nTPM]":"32.1","Cell RNA - HeLa [nTPM]":"8.2","Cell RNA - Hep G2 [nTPM]":"6.1","Cell RNA - HHSteC [nTPM]":"20.2","Cell RNA - HL-60 [nTPM]":"32.7","Cell RNA - HMC-1 [nTPM]":"36.4","Cell RNA - HSkMC [nTPM]":"17.4","Cell RNA - hTCEpi [nTPM]":"7.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"27.4","Cell RNA - hTERT-HME1 [nTPM]":"23.1","Cell RNA - hTERT-RPE1 [nTPM]":"7.5","Cell RNA - HUVEC TERT2 [nTPM]":"18.3","Cell RNA - JURKAT [nTPM]":"10.4","Cell RNA - K-562 [nTPM]":"3.0","Cell RNA - Karpas-707 [nTPM]":"36.2","Cell RNA - LHCN-M2 [nTPM]":"14.7","Cell RNA - MCF7 [nTPM]":"35.7","Cell RNA - MOLT-4 [nTPM]":"23.5","Cell RNA - NB-4 [nTPM]":"73.4","Cell RNA - NTERA-2 [nTPM]":"5.0","Cell RNA - OE19 [nTPM]":"11.3","Cell RNA - PC-3 [nTPM]":"16.1","Cell RNA - REH [nTPM]":"38.2","Cell RNA - RH-30 [nTPM]":"9.9","Cell RNA - RPMI-8226 [nTPM]":"17.7","Cell RNA - RPTEC TERT1 [nTPM]":"8.2","Cell RNA - RT4 [nTPM]":"27.6","Cell RNA - SCLC-21H [nTPM]":"8.3","Cell RNA - SH-SY5Y [nTPM]":"10.2","Cell RNA - SiHa [nTPM]":"16.4","Cell RNA - SK-BR-3 [nTPM]":"22.5","Cell RNA - SK-MEL-30 [nTPM]":"77.9","Cell RNA - SuSa [nTPM]":"15.6","Cell RNA - T-47d [nTPM]":"8.2","Cell RNA - THP-1 [nTPM]":"68.7","Cell RNA - TIME [nTPM]":"24.8","Cell RNA - U-138 MG [nTPM]":"22.3","Cell RNA - U-2 OS [nTPM]":"11.3","Cell RNA - U-2197 [nTPM]":"15.8","Cell RNA - U-251 MG [nTPM]":"15.5","Cell RNA - U-266\/70 [nTPM]":"30.2","Cell RNA - U-266\/84 [nTPM]":"48.4","Cell RNA - U-698 [nTPM]":"17.1","Cell RNA - U-87 MG [nTPM]":"29.4","Cell RNA - U-937 [nTPM]":"49.8","Cell RNA - WM-115 [nTPM]":"143.3","Blood RNA - basophil [nTPM]":"16.7","Blood RNA - classical monocyte [nTPM]":"26.5","Blood RNA - eosinophil [nTPM]":"23.4","Blood RNA - gdT-cell [nTPM]":"36.5","Blood RNA - intermediate monocyte [nTPM]":"46.3","Blood RNA - MAIT T-cell [nTPM]":"26.9","Blood RNA - memory B-cell [nTPM]":"10.0","Blood RNA - memory CD4 T-cell [nTPM]":"19.3","Blood RNA - memory CD8 T-cell [nTPM]":"26.3","Blood RNA - myeloid DC [nTPM]":"22.5","Blood RNA - naive B-cell [nTPM]":"8.1","Blood RNA - naive CD4 T-cell [nTPM]":"11.0","Blood RNA - naive CD8 T-cell [nTPM]":"20.0","Blood RNA - neutrophil [nTPM]":"48.9","Blood RNA - NK-cell [nTPM]":"16.9","Blood RNA - non-classical monocyte [nTPM]":"71.8","Blood RNA - plasmacytoid DC [nTPM]":"7.1","Blood RNA - T-reg [nTPM]":"26.7","Blood RNA - total PBMC [nTPM]":"44.0","Brain RNA - amygdala [nTPM]":"3.1","Brain RNA - basal ganglia [nTPM]":"3.6","Brain RNA - cerebellum [nTPM]":"18.4","Brain RNA - cerebral cortex [nTPM]":"5.6","Brain RNA - hippocampal formation [nTPM]":"3.1","Brain RNA - hypothalamus [nTPM]":"4.0","Brain RNA - medulla oblongata [nTPM]":"6.2","Brain RNA - midbrain [nTPM]":"4.4","Brain RNA - pons [nTPM]":"5.8","Brain RNA - spinal cord [nTPM]":"5.4","Brain RNA - thalamus [nTPM]":"6.4","Brain RNA - white matter [nTPM]":"7.0","Single Cell Type RNA - Adipocytes [nTPM]":"35.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.2","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"40.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"4.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"6.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.1","Single Cell Type RNA - dendritic cells [nTPM]":"107.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.5","Single Cell Type RNA - Early spermatids [nTPM]":"2.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.6","Single Cell Type RNA - Endothelial cells [nTPM]":"23.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.0","Single Cell Type RNA - Erythroid cells [nTPM]":"11.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"27.2","Single Cell Type RNA - Fibroblasts [nTPM]":"9.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.1","Single Cell Type RNA - granulocytes [nTPM]":"28.4","Single Cell Type RNA - Granulosa cells [nTPM]":"3.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.2","Single Cell Type RNA - Hepatocytes [nTPM]":"2.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"36.3","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.9","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"91.4","Single Cell Type RNA - Langerhans cells [nTPM]":"43.8","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"61.3","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"32.8","Single Cell Type RNA - monocytes [nTPM]":"49.8","Single Cell Type RNA - Muller glia cells [nTPM]":"2.1","Single Cell Type RNA - NK-cells [nTPM]":"171.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.7","Single Cell Type RNA - Paneth cells [nTPM]":"11.8","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"42.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.2","Single Cell Type RNA - Spermatocytes [nTPM]":"5.3","Single Cell Type RNA - Spermatogonia [nTPM]":"7.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.1","Single Cell Type RNA - T-cells [nTPM]":"81.4","Single Cell Type RNA - Theca cells [nTPM]":"11.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.3","Single Cell Type RNA - Urothelial cells [nTPM]":"10.7"},{"Gene":"STK11","Gene synonym":["LKB1","PJS"],"Ensembl":"ENSG00000118046","Gene description":"Serine\/threonine kinase 11","Uniprot":["Q15831"],"Chromosome":"19","Position":"1177558-1228431","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Autophagy","Cell cycle","Differentiation","DNA damage","Spermatogenesis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"154.9","Late spermatids":"338.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"9.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016231","HPA017254","CAB022105","HPA067481"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB016231":"AB_627890","CAB022105":null,"HPA017254":"AB_1852924","HPA067481":"AB_2685847"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.69e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.96e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-3"},"Tissue RNA - adipose tissue [nTPM]":"32.1","Tissue RNA - adrenal gland [nTPM]":"44.2","Tissue RNA - amygdala [nTPM]":"18.8","Tissue RNA - appendix [nTPM]":"18.2","Tissue RNA - basal ganglia [nTPM]":"15.5","Tissue RNA - bone marrow [nTPM]":"34.1","Tissue RNA - breast [nTPM]":"32.3","Tissue RNA - cerebellum [nTPM]":"24.8","Tissue RNA - cerebral cortex [nTPM]":"23.5","Tissue RNA - cervix [nTPM]":"35.4","Tissue RNA - choroid plexus [nTPM]":"24.7","Tissue RNA - colon [nTPM]":"38.7","Tissue RNA - duodenum [nTPM]":"25.6","Tissue RNA - endometrium 1 [nTPM]":"33.6","Tissue RNA - epididymis [nTPM]":"5.5","Tissue RNA - esophagus [nTPM]":"39.7","Tissue RNA - fallopian tube [nTPM]":"34.9","Tissue RNA - gallbladder [nTPM]":"11.8","Tissue RNA - heart muscle [nTPM]":"48.4","Tissue RNA - hippocampal formation [nTPM]":"18.3","Tissue RNA - hypothalamus [nTPM]":"14.7","Tissue RNA - kidney [nTPM]":"36.4","Tissue RNA - liver [nTPM]":"45.5","Tissue RNA - lung [nTPM]":"30.5","Tissue RNA - lymph node [nTPM]":"20.5","Tissue RNA - medulla oblongata [nTPM]":"19.2","Tissue RNA - midbrain [nTPM]":"19.4","Tissue RNA - ovary [nTPM]":"37.9","Tissue RNA - pancreas [nTPM]":"34.2","Tissue RNA - parathyroid gland [nTPM]":"16.1","Tissue RNA - pituitary gland [nTPM]":"36.8","Tissue RNA - placenta [nTPM]":"12.6","Tissue RNA - pons [nTPM]":"15.2","Tissue RNA - prostate [nTPM]":"39.3","Tissue RNA - rectum [nTPM]":"7.7","Tissue RNA - retina [nTPM]":"5.7","Tissue RNA - salivary gland [nTPM]":"29.7","Tissue RNA - seminal vesicle [nTPM]":"16.1","Tissue RNA - skeletal muscle [nTPM]":"108.2","Tissue RNA - skin 1 [nTPM]":"40.2","Tissue RNA - small intestine [nTPM]":"37.7","Tissue RNA - smooth muscle [nTPM]":"9.6","Tissue RNA - spinal cord [nTPM]":"16.3","Tissue RNA - spleen [nTPM]":"48.3","Tissue RNA - stomach 1 [nTPM]":"38.1","Tissue RNA - testis [nTPM]":"102.4","Tissue RNA - thalamus [nTPM]":"17.6","Tissue RNA - thymus [nTPM]":"15.0","Tissue RNA - thyroid gland [nTPM]":"34.3","Tissue RNA - tongue [nTPM]":"27.7","Tissue RNA - tonsil [nTPM]":"12.9","Tissue RNA - urinary bladder [nTPM]":"34.4","Tissue RNA - vagina [nTPM]":"35.0","Tissue RNA - white matter [nTPM]":"14.9","Cell RNA - A-431 [nTPM]":"50.0","Cell RNA - A549 [nTPM]":"25.8","Cell RNA - AF22 [nTPM]":"19.9","Cell RNA - AN3-CA [nTPM]":"35.9","Cell RNA - ASC diff [nTPM]":"18.6","Cell RNA - ASC TERT1 [nTPM]":"17.0","Cell RNA - BEWO [nTPM]":"35.5","Cell RNA - BJ [nTPM]":"24.0","Cell RNA - BJ hTERT+ [nTPM]":"27.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"25.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"25.4","Cell RNA - CACO-2 [nTPM]":"22.5","Cell RNA - CAPAN-2 [nTPM]":"37.1","Cell RNA - Daudi [nTPM]":"31.9","Cell RNA - EFO-21 [nTPM]":"24.8","Cell RNA - fHDF\/TERT166 [nTPM]":"27.8","Cell RNA - GAMG [nTPM]":"11.2","Cell RNA - HaCaT [nTPM]":"32.3","Cell RNA - HAP1 [nTPM]":"20.1","Cell RNA - HBEC3-KT [nTPM]":"41.9","Cell RNA - HBF TERT88 [nTPM]":"8.2","Cell RNA - HDLM-2 [nTPM]":"60.2","Cell RNA - HEK 293 [nTPM]":"37.8","Cell RNA - HEL [nTPM]":"34.8","Cell RNA - HeLa [nTPM]":"1.7","Cell RNA - Hep G2 [nTPM]":"26.4","Cell RNA - HHSteC [nTPM]":"38.1","Cell RNA - HL-60 [nTPM]":"36.6","Cell RNA - HMC-1 [nTPM]":"53.5","Cell RNA - HSkMC [nTPM]":"30.5","Cell RNA - hTCEpi [nTPM]":"28.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.4","Cell RNA - hTERT-HME1 [nTPM]":"29.2","Cell RNA - hTERT-RPE1 [nTPM]":"22.3","Cell RNA - HUVEC TERT2 [nTPM]":"25.2","Cell RNA - JURKAT [nTPM]":"28.1","Cell RNA - K-562 [nTPM]":"63.1","Cell RNA - Karpas-707 [nTPM]":"51.1","Cell RNA - LHCN-M2 [nTPM]":"13.9","Cell RNA - MCF7 [nTPM]":"39.3","Cell RNA - MOLT-4 [nTPM]":"31.9","Cell RNA - NB-4 [nTPM]":"27.7","Cell RNA - NTERA-2 [nTPM]":"33.0","Cell RNA - OE19 [nTPM]":"19.6","Cell RNA - PC-3 [nTPM]":"25.1","Cell RNA - REH [nTPM]":"50.0","Cell RNA - RH-30 [nTPM]":"20.0","Cell RNA - RPMI-8226 [nTPM]":"36.1","Cell RNA - RPTEC TERT1 [nTPM]":"21.1","Cell RNA - RT4 [nTPM]":"39.7","Cell RNA - SCLC-21H [nTPM]":"39.8","Cell RNA - SH-SY5Y [nTPM]":"26.6","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"19.7","Cell RNA - SK-MEL-30 [nTPM]":"24.2","Cell RNA - SuSa [nTPM]":"11.4","Cell RNA - T-47d [nTPM]":"30.3","Cell RNA - THP-1 [nTPM]":"55.2","Cell RNA - TIME [nTPM]":"33.7","Cell RNA - U-138 MG [nTPM]":"24.6","Cell RNA - U-2 OS [nTPM]":"25.0","Cell RNA - U-2197 [nTPM]":"45.2","Cell RNA - U-251 MG [nTPM]":"38.7","Cell RNA - U-266\/70 [nTPM]":"85.3","Cell RNA - U-266\/84 [nTPM]":"38.1","Cell RNA - U-698 [nTPM]":"25.7","Cell RNA - U-87 MG [nTPM]":"22.6","Cell RNA - U-937 [nTPM]":"48.1","Cell RNA - WM-115 [nTPM]":"25.5","Blood RNA - basophil [nTPM]":"1.7","Blood RNA - classical monocyte [nTPM]":"3.3","Blood RNA - eosinophil [nTPM]":"3.9","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"5.5","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"2.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"1.6","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"9.9","Blood RNA - NK-cell [nTPM]":"1.4","Blood RNA - non-classical monocyte [nTPM]":"5.7","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"18.8","Brain RNA - basal ganglia [nTPM]":"15.5","Brain RNA - cerebellum [nTPM]":"24.8","Brain RNA - cerebral cortex [nTPM]":"23.5","Brain RNA - hippocampal formation [nTPM]":"18.3","Brain RNA - hypothalamus [nTPM]":"14.7","Brain RNA - medulla oblongata [nTPM]":"19.2","Brain RNA - midbrain [nTPM]":"19.4","Brain RNA - pons [nTPM]":"15.2","Brain RNA - spinal cord [nTPM]":"16.3","Brain RNA - thalamus [nTPM]":"17.6","Brain RNA - white matter [nTPM]":"14.9","Single Cell Type RNA - Adipocytes [nTPM]":"24.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.7","Single Cell Type RNA - Astrocytes [nTPM]":"12.7","Single Cell Type RNA - B-cells [nTPM]":"10.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"25.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"9.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.5","Single Cell Type RNA - dendritic cells [nTPM]":"20.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.4","Single Cell Type RNA - Early spermatids [nTPM]":"154.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.1","Single Cell Type RNA - Endothelial cells [nTPM]":"15.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.0","Single Cell Type RNA - Erythroid cells [nTPM]":"27.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.3","Single Cell Type RNA - Fibroblasts [nTPM]":"13.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.8","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"80.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.4","Single Cell Type RNA - Hepatocytes [nTPM]":"31.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.2","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"33.1","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"18.3","Single Cell Type RNA - Langerhans cells [nTPM]":"26.4","Single Cell Type RNA - Late spermatids [nTPM]":"338.7","Single Cell Type RNA - Leydig cells [nTPM]":"24.5","Single Cell Type RNA - Macrophages [nTPM]":"20.7","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"20.4","Single Cell Type RNA - Muller glia cells [nTPM]":"21.2","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.7","Single Cell Type RNA - Paneth cells [nTPM]":"29.3","Single Cell Type RNA - Peritubular cells [nTPM]":"20.7","Single Cell Type RNA - Plasma cells [nTPM]":"10.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"27.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.7","Single Cell Type RNA - Spermatocytes [nTPM]":"85.5","Single Cell Type RNA - Spermatogonia [nTPM]":"20.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.8","Single Cell Type RNA - T-cells [nTPM]":"16.6","Single Cell Type RNA - Theca cells [nTPM]":"45.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"35.4","Single Cell Type RNA - Urothelial cells [nTPM]":"12.6"},{"Gene":"STK19","Gene synonym":["D6S60","G11","RP1"],"Ensembl":"ENSG00000204344","Gene description":"Serine\/threonine kinase 19","Uniprot":["P49842"],"Chromosome":"6","Position":"31971091-31982821","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Proximal tubular cells":"348.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"1.4","HEL":"1.5","HL-60":"1.6","REH":"1.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031511","HPA068559"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA031511":"AB_2673915","HPA068559":"AB_2686004"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.18e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.5","Tissue RNA - adrenal gland [nTPM]":"3.6","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.3","Tissue RNA - cerebellum [nTPM]":"0.4","Tissue RNA - cerebral cortex [nTPM]":"0.9","Tissue RNA - cervix [nTPM]":"2.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"2.5","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"1.4","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"1.9","Tissue RNA - fallopian tube [nTPM]":"1.0","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"1.2","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"1.5","Tissue RNA - liver [nTPM]":"2.2","Tissue RNA - lung [nTPM]":"1.3","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"1.1","Tissue RNA - pancreas [nTPM]":"1.1","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"1.4","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"2.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"0.9","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"1.3","Tissue RNA - skin 1 [nTPM]":"2.5","Tissue RNA - small intestine [nTPM]":"0.7","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"1.2","Tissue RNA - stomach 1 [nTPM]":"1.3","Tissue RNA - testis [nTPM]":"1.5","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"1.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"2.0","Tissue RNA - vagina [nTPM]":"1.5","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"1.1","Cell RNA - ASC TERT1 [nTPM]":"0.7","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.7","Cell RNA - Daudi [nTPM]":"0.6","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.5","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.6","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"1.4","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"1.5","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.5","Cell RNA - HL-60 [nTPM]":"1.6","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.6","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.3","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"1.7","Cell RNA - RH-30 [nTPM]":"1.1","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.7","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.9","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.7","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.8","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.4","Brain RNA - cerebral cortex [nTPM]":"0.9","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"21.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.5","Single Cell Type RNA - Astrocytes [nTPM]":"13.7","Single Cell Type RNA - B-cells [nTPM]":"16.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"23.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"11.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"27.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"24.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"37.2","Single Cell Type RNA - dendritic cells [nTPM]":"22.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"39.2","Single Cell Type RNA - Ductal cells [nTPM]":"26.3","Single Cell Type RNA - Early spermatids [nTPM]":"85.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"31.8","Single Cell Type RNA - Endothelial cells [nTPM]":"20.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.3","Single Cell Type RNA - Erythroid cells [nTPM]":"4.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"28.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.0","Single Cell Type RNA - Fibroblasts [nTPM]":"23.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.7","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"20.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.3","Single Cell Type RNA - Hepatocytes [nTPM]":"21.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.3","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.3","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"8.8","Single Cell Type RNA - Langerhans cells [nTPM]":"10.0","Single Cell Type RNA - Late spermatids [nTPM]":"76.0","Single Cell Type RNA - Leydig cells [nTPM]":"20.2","Single Cell Type RNA - Macrophages [nTPM]":"18.3","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"12.5","Single Cell Type RNA - Muller glia cells [nTPM]":"30.2","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"23.6","Single Cell Type RNA - Paneth cells [nTPM]":"16.4","Single Cell Type RNA - Peritubular cells [nTPM]":"18.4","Single Cell Type RNA - Plasma cells [nTPM]":"11.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"348.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"41.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.9","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.1","Single Cell Type RNA - Spermatocytes [nTPM]":"39.5","Single Cell Type RNA - Spermatogonia [nTPM]":"21.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"49.7","Single Cell Type RNA - T-cells [nTPM]":"19.8","Single Cell Type RNA - Theca cells [nTPM]":"45.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.1","Single Cell Type RNA - Urothelial cells [nTPM]":"11.8"},{"Gene":"STK4","Gene synonym":["KRS2","MST1","YSK3"],"Ensembl":"ENSG00000101109","Gene description":"Serine\/threonine kinase 4","Uniprot":["Q13043"],"Chromosome":"20","Position":"44966479-45080021","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["Apoptosis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"57.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"372.8","dendritic cells":"341.8","Langerhans cells":"606.9","monocytes":"367.5","Plasma cells":"336.2","T-cells":"414.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004038","HPA015270"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"45000","Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"CAB004038":"AB_2144632","HPA015270":"AB_1854150"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.49e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.04e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.84e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.0","Tissue RNA - adrenal gland [nTPM]":"8.5","Tissue RNA - amygdala [nTPM]":"6.9","Tissue RNA - appendix [nTPM]":"33.8","Tissue RNA - basal ganglia [nTPM]":"8.0","Tissue RNA - bone marrow [nTPM]":"57.7","Tissue RNA - breast [nTPM]":"9.1","Tissue RNA - cerebellum [nTPM]":"6.2","Tissue RNA - cerebral cortex [nTPM]":"10.8","Tissue RNA - cervix [nTPM]":"7.9","Tissue RNA - choroid plexus [nTPM]":"9.9","Tissue RNA - colon [nTPM]":"11.1","Tissue RNA - duodenum [nTPM]":"10.2","Tissue RNA - endometrium 1 [nTPM]":"8.5","Tissue RNA - epididymis [nTPM]":"7.6","Tissue RNA - esophagus [nTPM]":"9.1","Tissue RNA - fallopian tube [nTPM]":"6.2","Tissue RNA - gallbladder [nTPM]":"11.7","Tissue RNA - heart muscle [nTPM]":"4.6","Tissue RNA - hippocampal formation [nTPM]":"7.2","Tissue RNA - hypothalamus [nTPM]":"8.7","Tissue RNA - kidney [nTPM]":"6.0","Tissue RNA - liver [nTPM]":"9.2","Tissue RNA - lung [nTPM]":"15.9","Tissue RNA - lymph node [nTPM]":"43.1","Tissue RNA - medulla oblongata [nTPM]":"8.7","Tissue RNA - midbrain [nTPM]":"7.6","Tissue RNA - ovary [nTPM]":"7.0","Tissue RNA - pancreas [nTPM]":"6.0","Tissue RNA - parathyroid gland [nTPM]":"5.9","Tissue RNA - pituitary gland [nTPM]":"4.1","Tissue RNA - placenta [nTPM]":"10.4","Tissue RNA - pons [nTPM]":"9.2","Tissue RNA - prostate [nTPM]":"6.7","Tissue RNA - rectum [nTPM]":"13.0","Tissue RNA - retina [nTPM]":"7.3","Tissue RNA - salivary gland [nTPM]":"7.4","Tissue RNA - seminal vesicle [nTPM]":"8.0","Tissue RNA - skeletal muscle [nTPM]":"3.3","Tissue RNA - skin 1 [nTPM]":"11.2","Tissue RNA - small intestine [nTPM]":"13.5","Tissue RNA - smooth muscle [nTPM]":"9.3","Tissue RNA - spinal cord [nTPM]":"8.3","Tissue RNA - spleen [nTPM]":"30.4","Tissue RNA - stomach 1 [nTPM]":"12.7","Tissue RNA - testis [nTPM]":"9.7","Tissue RNA - thalamus [nTPM]":"7.5","Tissue RNA - thymus [nTPM]":"33.1","Tissue RNA - thyroid gland [nTPM]":"7.6","Tissue RNA - tongue [nTPM]":"4.9","Tissue RNA - tonsil [nTPM]":"41.7","Tissue RNA - urinary bladder [nTPM]":"15.0","Tissue RNA - vagina [nTPM]":"6.9","Tissue RNA - white matter [nTPM]":"10.3","Cell RNA - A-431 [nTPM]":"27.8","Cell RNA - A549 [nTPM]":"18.7","Cell RNA - AF22 [nTPM]":"23.3","Cell RNA - AN3-CA [nTPM]":"16.1","Cell RNA - ASC diff [nTPM]":"13.5","Cell RNA - ASC TERT1 [nTPM]":"16.9","Cell RNA - BEWO [nTPM]":"16.0","Cell RNA - BJ [nTPM]":"23.6","Cell RNA - BJ hTERT+ [nTPM]":"35.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"39.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"35.6","Cell RNA - CACO-2 [nTPM]":"52.7","Cell RNA - CAPAN-2 [nTPM]":"14.6","Cell RNA - Daudi [nTPM]":"66.6","Cell RNA - EFO-21 [nTPM]":"20.4","Cell RNA - fHDF\/TERT166 [nTPM]":"16.9","Cell RNA - GAMG [nTPM]":"33.4","Cell RNA - HaCaT [nTPM]":"28.5","Cell RNA - HAP1 [nTPM]":"24.3","Cell RNA - HBEC3-KT [nTPM]":"31.8","Cell RNA - HBF TERT88 [nTPM]":"49.7","Cell RNA - HDLM-2 [nTPM]":"30.8","Cell RNA - HEK 293 [nTPM]":"13.8","Cell RNA - HEL [nTPM]":"48.6","Cell RNA - HeLa [nTPM]":"27.8","Cell RNA - Hep G2 [nTPM]":"36.8","Cell RNA - HHSteC [nTPM]":"23.8","Cell RNA - HL-60 [nTPM]":"63.5","Cell RNA - HMC-1 [nTPM]":"66.4","Cell RNA - HSkMC [nTPM]":"13.8","Cell RNA - hTCEpi [nTPM]":"25.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"36.7","Cell RNA - hTERT-HME1 [nTPM]":"39.6","Cell RNA - hTERT-RPE1 [nTPM]":"19.4","Cell RNA - HUVEC TERT2 [nTPM]":"14.6","Cell RNA - JURKAT [nTPM]":"44.6","Cell RNA - K-562 [nTPM]":"23.5","Cell RNA - Karpas-707 [nTPM]":"37.0","Cell RNA - LHCN-M2 [nTPM]":"19.9","Cell RNA - MCF7 [nTPM]":"21.7","Cell RNA - MOLT-4 [nTPM]":"47.6","Cell RNA - NB-4 [nTPM]":"42.3","Cell RNA - NTERA-2 [nTPM]":"13.9","Cell RNA - OE19 [nTPM]":"17.7","Cell RNA - PC-3 [nTPM]":"12.5","Cell RNA - REH [nTPM]":"30.2","Cell RNA - RH-30 [nTPM]":"25.2","Cell RNA - RPMI-8226 [nTPM]":"31.2","Cell RNA - RPTEC TERT1 [nTPM]":"14.4","Cell RNA - RT4 [nTPM]":"18.7","Cell RNA - SCLC-21H [nTPM]":"10.9","Cell RNA - SH-SY5Y [nTPM]":"13.2","Cell RNA - SiHa [nTPM]":"35.6","Cell RNA - SK-BR-3 [nTPM]":"20.0","Cell RNA - SK-MEL-30 [nTPM]":"27.0","Cell RNA - SuSa [nTPM]":"17.2","Cell RNA - T-47d [nTPM]":"18.3","Cell RNA - THP-1 [nTPM]":"39.1","Cell RNA - TIME [nTPM]":"18.7","Cell RNA - U-138 MG [nTPM]":"29.2","Cell RNA - U-2 OS [nTPM]":"28.6","Cell RNA - U-2197 [nTPM]":"34.4","Cell RNA - U-251 MG [nTPM]":"27.8","Cell RNA - U-266\/70 [nTPM]":"48.4","Cell RNA - U-266\/84 [nTPM]":"41.7","Cell RNA - U-698 [nTPM]":"73.2","Cell RNA - U-87 MG [nTPM]":"28.6","Cell RNA - U-937 [nTPM]":"29.5","Cell RNA - WM-115 [nTPM]":"22.0","Blood RNA - basophil [nTPM]":"80.6","Blood RNA - classical monocyte [nTPM]":"19.7","Blood RNA - eosinophil [nTPM]":"54.8","Blood RNA - gdT-cell [nTPM]":"34.4","Blood RNA - intermediate monocyte [nTPM]":"19.9","Blood RNA - MAIT T-cell [nTPM]":"34.3","Blood RNA - memory B-cell [nTPM]":"26.2","Blood RNA - memory CD4 T-cell [nTPM]":"32.2","Blood RNA - memory CD8 T-cell [nTPM]":"32.0","Blood RNA - myeloid DC [nTPM]":"18.4","Blood RNA - naive B-cell [nTPM]":"26.9","Blood RNA - naive CD4 T-cell [nTPM]":"33.1","Blood RNA - naive CD8 T-cell [nTPM]":"28.0","Blood RNA - neutrophil [nTPM]":"101.8","Blood RNA - NK-cell [nTPM]":"28.5","Blood RNA - non-classical monocyte [nTPM]":"38.0","Blood RNA - plasmacytoid DC [nTPM]":"10.0","Blood RNA - T-reg [nTPM]":"34.3","Blood RNA - total PBMC [nTPM]":"22.3","Brain RNA - amygdala [nTPM]":"6.9","Brain RNA - basal ganglia [nTPM]":"8.0","Brain RNA - cerebellum [nTPM]":"6.2","Brain RNA - cerebral cortex [nTPM]":"10.8","Brain RNA - hippocampal formation [nTPM]":"7.2","Brain RNA - hypothalamus [nTPM]":"8.7","Brain RNA - medulla oblongata [nTPM]":"8.7","Brain RNA - midbrain [nTPM]":"7.6","Brain RNA - pons [nTPM]":"9.2","Brain RNA - spinal cord [nTPM]":"8.3","Brain RNA - thalamus [nTPM]":"7.5","Brain RNA - white matter [nTPM]":"10.3","Single Cell Type RNA - Adipocytes [nTPM]":"26.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"24.6","Single Cell Type RNA - Astrocytes [nTPM]":"18.9","Single Cell Type RNA - B-cells [nTPM]":"372.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"55.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"49.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"33.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"28.5","Single Cell Type RNA - Bipolar cells [nTPM]":"27.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"25.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"42.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"24.1","Single Cell Type RNA - dendritic cells [nTPM]":"341.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"16.3","Single Cell Type RNA - Early spermatids [nTPM]":"5.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"25.1","Single Cell Type RNA - Endothelial cells [nTPM]":"32.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"25.7","Single Cell Type RNA - Erythroid cells [nTPM]":"46.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"76.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"30.3","Single Cell Type RNA - Fibroblasts [nTPM]":"29.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"34.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.1","Single Cell Type RNA - granulocytes [nTPM]":"133.6","Single Cell Type RNA - Granulosa cells [nTPM]":"114.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.0","Single Cell Type RNA - Hepatocytes [nTPM]":"22.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"61.1","Single Cell Type RNA - Horizontal cells [nTPM]":"43.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"38.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.7","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"109.3","Single Cell Type RNA - Langerhans cells [nTPM]":"606.9","Single Cell Type RNA - Late spermatids [nTPM]":"5.0","Single Cell Type RNA - Leydig cells [nTPM]":"22.7","Single Cell Type RNA - Macrophages [nTPM]":"154.4","Single Cell Type RNA - Melanocytes [nTPM]":"133.4","Single Cell Type RNA - Microglial cells [nTPM]":"85.3","Single Cell Type RNA - monocytes [nTPM]":"367.5","Single Cell Type RNA - Muller glia cells [nTPM]":"20.2","Single Cell Type RNA - NK-cells [nTPM]":"278.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"34.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"48.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.6","Single Cell Type RNA - Paneth cells [nTPM]":"27.9","Single Cell Type RNA - Peritubular cells [nTPM]":"17.0","Single Cell Type RNA - Plasma cells [nTPM]":"336.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"32.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"26.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"69.9","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"25.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"29.2","Single Cell Type RNA - Spermatocytes [nTPM]":"44.2","Single Cell Type RNA - Spermatogonia [nTPM]":"42.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"53.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"19.4","Single Cell Type RNA - T-cells [nTPM]":"414.5","Single Cell Type RNA - Theca cells [nTPM]":"48.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.5","Single Cell Type RNA - Urothelial cells [nTPM]":"45.5"},{"Gene":"STRA6","Gene synonym":["FLJ12541"],"Ensembl":"ENSG00000137868","Gene description":"Signaling receptor and transporter of retinol STRA6","Uniprot":["Q9BX79"],"Chromosome":"15","Position":"74179466-74212267","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Receptor"],"Disease involvement":["Disease variant","Microphthalmia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"24.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Club cells":"17.6","Endometrial stromal cells":"43.1","Extravillous trophoblasts":"12.1","Fibroblasts":"16.1","Proximal tubular cells":"10.3","Syncytiotrophoblasts":"26.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"33.7","CAPAN-2":"94.5","SH-SY5Y":"59.2","WM-115":"142.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040839"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA040839":"AB_10794881"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"1.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.9","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"24.5","Tissue RNA - choroid plexus [nTPM]":"0.4","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"4.3","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"1.1","Tissue RNA - fallopian tube [nTPM]":"3.6","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"4.3","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.8","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"5.5","Tissue RNA - placenta [nTPM]":"7.6","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"5.2","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.7","Tissue RNA - seminal vesicle [nTPM]":"1.4","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"3.1","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"1.3","Tissue RNA - vagina [nTPM]":"2.4","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.5","Cell RNA - A549 [nTPM]":"33.7","Cell RNA - AF22 [nTPM]":"1.9","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"6.0","Cell RNA - BJ [nTPM]":"1.0","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"11.7","Cell RNA - CAPAN-2 [nTPM]":"94.5","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"22.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.7","Cell RNA - HaCaT [nTPM]":"3.4","Cell RNA - HAP1 [nTPM]":"1.8","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"3.0","Cell RNA - HeLa [nTPM]":"1.3","Cell RNA - Hep G2 [nTPM]":"2.5","Cell RNA - HHSteC [nTPM]":"0.5","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"6.1","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"2.9","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"2.9","Cell RNA - SCLC-21H [nTPM]":"17.4","Cell RNA - SH-SY5Y [nTPM]":"59.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"3.6","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"3.6","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"7.3","Cell RNA - U-2197 [nTPM]":"0.6","Cell RNA - U-251 MG [nTPM]":"1.6","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.6","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"142.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"17.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"43.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.1","Single Cell Type RNA - Fibroblasts [nTPM]":"16.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"6.8","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"26.4","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"STRADA","Gene synonym":["LYK5","NY-BR-96","Stlk","STRAD"],"Ensembl":"ENSG00000266173","Gene description":"STE20 related adaptor alpha","Uniprot":["Q7RTN6"],"Chromosome":"17","Position":"63682336-63741986","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"48.0","Excitatory neurons":"49.1","Inhibitory neurons":"47.5","Oligodendrocyte precursor cells":"33.2","Oligodendrocytes":"71.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031637"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA031637":"AB_10601718"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.56e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.79e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.34e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.08e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.43e-4"},"Tissue RNA - adipose tissue [nTPM]":"21.3","Tissue RNA - adrenal gland [nTPM]":"28.3","Tissue RNA - amygdala [nTPM]":"32.2","Tissue RNA - appendix [nTPM]":"12.7","Tissue RNA - basal ganglia [nTPM]":"32.9","Tissue RNA - bone marrow [nTPM]":"18.3","Tissue RNA - breast [nTPM]":"19.6","Tissue RNA - cerebellum [nTPM]":"31.9","Tissue RNA - cerebral cortex [nTPM]":"35.8","Tissue RNA - cervix [nTPM]":"23.9","Tissue RNA - choroid plexus [nTPM]":"30.0","Tissue RNA - colon [nTPM]":"23.0","Tissue RNA - duodenum [nTPM]":"8.8","Tissue RNA - endometrium 1 [nTPM]":"20.5","Tissue RNA - epididymis [nTPM]":"18.2","Tissue RNA - esophagus [nTPM]":"21.1","Tissue RNA - fallopian tube [nTPM]":"23.0","Tissue RNA - gallbladder [nTPM]":"13.4","Tissue RNA - heart muscle [nTPM]":"23.1","Tissue RNA - hippocampal formation [nTPM]":"32.9","Tissue RNA - hypothalamus [nTPM]":"32.6","Tissue RNA - kidney [nTPM]":"27.8","Tissue RNA - liver [nTPM]":"23.0","Tissue RNA - lung [nTPM]":"19.0","Tissue RNA - lymph node [nTPM]":"20.3","Tissue RNA - medulla oblongata [nTPM]":"34.3","Tissue RNA - midbrain [nTPM]":"31.8","Tissue RNA - ovary [nTPM]":"24.7","Tissue RNA - pancreas [nTPM]":"17.7","Tissue RNA - parathyroid gland [nTPM]":"19.1","Tissue RNA - pituitary gland [nTPM]":"26.4","Tissue RNA - placenta [nTPM]":"13.4","Tissue RNA - pons [nTPM]":"32.6","Tissue RNA - prostate [nTPM]":"22.5","Tissue RNA - rectum [nTPM]":"11.6","Tissue RNA - retina [nTPM]":"13.9","Tissue RNA - salivary gland [nTPM]":"15.6","Tissue RNA - seminal vesicle [nTPM]":"14.3","Tissue RNA - skeletal muscle [nTPM]":"14.6","Tissue RNA - skin 1 [nTPM]":"20.8","Tissue RNA - small intestine [nTPM]":"19.4","Tissue RNA - smooth muscle [nTPM]":"17.2","Tissue RNA - spinal cord [nTPM]":"31.0","Tissue RNA - spleen [nTPM]":"32.0","Tissue RNA - stomach 1 [nTPM]":"20.5","Tissue RNA - testis [nTPM]":"49.0","Tissue RNA - thalamus [nTPM]":"32.4","Tissue RNA - thymus [nTPM]":"20.1","Tissue RNA - thyroid gland [nTPM]":"20.0","Tissue RNA - tongue [nTPM]":"10.1","Tissue RNA - tonsil [nTPM]":"20.4","Tissue RNA - urinary bladder [nTPM]":"22.6","Tissue RNA - vagina [nTPM]":"20.0","Tissue RNA - white matter [nTPM]":"32.8","Cell RNA - A-431 [nTPM]":"12.7","Cell RNA - A549 [nTPM]":"37.5","Cell RNA - AF22 [nTPM]":"31.9","Cell RNA - AN3-CA [nTPM]":"32.3","Cell RNA - ASC diff [nTPM]":"30.8","Cell RNA - ASC TERT1 [nTPM]":"22.8","Cell RNA - BEWO [nTPM]":"12.4","Cell RNA - BJ [nTPM]":"23.8","Cell RNA - BJ hTERT+ [nTPM]":"21.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"33.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"29.8","Cell RNA - CACO-2 [nTPM]":"9.9","Cell RNA - CAPAN-2 [nTPM]":"14.4","Cell RNA - Daudi [nTPM]":"19.5","Cell RNA - EFO-21 [nTPM]":"14.4","Cell RNA - fHDF\/TERT166 [nTPM]":"20.3","Cell RNA - GAMG [nTPM]":"16.7","Cell RNA - HaCaT [nTPM]":"10.5","Cell RNA - HAP1 [nTPM]":"21.4","Cell RNA - HBEC3-KT [nTPM]":"23.1","Cell RNA - HBF TERT88 [nTPM]":"33.0","Cell RNA - HDLM-2 [nTPM]":"21.5","Cell RNA - HEK 293 [nTPM]":"20.7","Cell RNA - HEL [nTPM]":"38.4","Cell RNA - HeLa [nTPM]":"25.9","Cell RNA - Hep G2 [nTPM]":"23.7","Cell RNA - HHSteC [nTPM]":"21.8","Cell RNA - HL-60 [nTPM]":"36.7","Cell RNA - HMC-1 [nTPM]":"26.5","Cell RNA - HSkMC [nTPM]":"23.9","Cell RNA - hTCEpi [nTPM]":"19.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"38.2","Cell RNA - hTERT-HME1 [nTPM]":"22.1","Cell RNA - hTERT-RPE1 [nTPM]":"22.3","Cell RNA - HUVEC TERT2 [nTPM]":"37.6","Cell RNA - JURKAT [nTPM]":"30.0","Cell RNA - K-562 [nTPM]":"24.9","Cell RNA - Karpas-707 [nTPM]":"20.0","Cell RNA - LHCN-M2 [nTPM]":"32.2","Cell RNA - MCF7 [nTPM]":"23.6","Cell RNA - MOLT-4 [nTPM]":"43.4","Cell RNA - NB-4 [nTPM]":"25.0","Cell RNA - NTERA-2 [nTPM]":"16.0","Cell RNA - OE19 [nTPM]":"10.7","Cell RNA - PC-3 [nTPM]":"21.2","Cell RNA - REH [nTPM]":"27.9","Cell RNA - RH-30 [nTPM]":"50.8","Cell RNA - RPMI-8226 [nTPM]":"23.8","Cell RNA - RPTEC TERT1 [nTPM]":"30.2","Cell RNA - RT4 [nTPM]":"24.9","Cell RNA - SCLC-21H [nTPM]":"36.0","Cell RNA - SH-SY5Y [nTPM]":"39.4","Cell RNA - SiHa [nTPM]":"16.3","Cell RNA - SK-BR-3 [nTPM]":"26.3","Cell RNA - SK-MEL-30 [nTPM]":"26.1","Cell RNA - SuSa [nTPM]":"32.9","Cell RNA - T-47d [nTPM]":"19.7","Cell RNA - THP-1 [nTPM]":"26.4","Cell RNA - TIME [nTPM]":"30.5","Cell RNA - U-138 MG [nTPM]":"31.7","Cell RNA - U-2 OS [nTPM]":"22.5","Cell RNA - U-2197 [nTPM]":"25.8","Cell RNA - U-251 MG [nTPM]":"20.0","Cell RNA - U-266\/70 [nTPM]":"19.9","Cell RNA - U-266\/84 [nTPM]":"22.9","Cell RNA - U-698 [nTPM]":"24.3","Cell RNA - U-87 MG [nTPM]":"23.4","Cell RNA - U-937 [nTPM]":"21.8","Cell RNA - WM-115 [nTPM]":"25.7","Blood RNA - basophil [nTPM]":"19.2","Blood RNA - classical monocyte [nTPM]":"9.5","Blood RNA - eosinophil [nTPM]":"8.8","Blood RNA - gdT-cell [nTPM]":"9.6","Blood RNA - intermediate monocyte [nTPM]":"6.9","Blood RNA - MAIT T-cell [nTPM]":"8.8","Blood RNA - memory B-cell [nTPM]":"10.3","Blood RNA - memory CD4 T-cell [nTPM]":"8.7","Blood RNA - memory CD8 T-cell [nTPM]":"10.7","Blood RNA - myeloid DC [nTPM]":"15.8","Blood RNA - naive B-cell [nTPM]":"7.5","Blood RNA - naive CD4 T-cell [nTPM]":"8.5","Blood RNA - naive CD8 T-cell [nTPM]":"7.6","Blood RNA - neutrophil [nTPM]":"10.8","Blood RNA - NK-cell [nTPM]":"16.8","Blood RNA - non-classical monocyte [nTPM]":"10.7","Blood RNA - plasmacytoid DC [nTPM]":"13.3","Blood RNA - T-reg [nTPM]":"7.3","Blood RNA - total PBMC [nTPM]":"8.0","Brain RNA - amygdala [nTPM]":"32.2","Brain RNA - basal ganglia [nTPM]":"32.9","Brain RNA - cerebellum [nTPM]":"31.9","Brain RNA - cerebral cortex [nTPM]":"35.8","Brain RNA - hippocampal formation [nTPM]":"32.9","Brain RNA - hypothalamus [nTPM]":"32.6","Brain RNA - medulla oblongata [nTPM]":"34.3","Brain RNA - midbrain [nTPM]":"31.8","Brain RNA - pons [nTPM]":"32.6","Brain RNA - spinal cord [nTPM]":"31.0","Brain RNA - thalamus [nTPM]":"32.4","Brain RNA - white matter [nTPM]":"32.8","Single Cell Type RNA - Adipocytes [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.3","Single Cell Type RNA - Astrocytes [nTPM]":"48.0","Single Cell Type RNA - B-cells [nTPM]":"12.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"2.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.1","Single Cell Type RNA - dendritic cells [nTPM]":"9.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"7.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.4","Single Cell Type RNA - Endothelial cells [nTPM]":"3.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"3.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"49.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.9","Single Cell Type RNA - Fibroblasts [nTPM]":"4.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.2","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"12.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.5","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"47.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.2","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1.4","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"6.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"27.2","Single Cell Type RNA - monocytes [nTPM]":"17.9","Single Cell Type RNA - Muller glia cells [nTPM]":"1.2","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"33.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"71.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.8","Single Cell Type RNA - Paneth cells [nTPM]":"2.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"10.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.1","Single Cell Type RNA - Spermatocytes [nTPM]":"3.1","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - T-cells [nTPM]":"9.1","Single Cell Type RNA - Theca cells [nTPM]":"9.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"STS","Gene synonym":["ARSC","ARSC1"],"Ensembl":"ENSG00000101846","Gene description":"Steroid sulfatase","Uniprot":["P08842"],"Chromosome":"X","Position":"7147237-7804358","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Pregnancy","Steroid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"26.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"41.8","Excitatory neurons":"32.2","Inhibitory neurons":"39.3","Syncytiotrophoblasts":"94.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"48.5","RPMI-8226":"69.8","U-266\/70":"110.2","U-698":"47.2"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002904"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA002904":"AB_1080116"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.47e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Tissue RNA - adipose tissue [nTPM]":"18.2","Tissue RNA - adrenal gland [nTPM]":"4.6","Tissue RNA - amygdala [nTPM]":"3.7","Tissue RNA - appendix [nTPM]":"4.5","Tissue RNA - basal ganglia [nTPM]":"4.8","Tissue RNA - bone marrow [nTPM]":"2.1","Tissue RNA - breast [nTPM]":"5.8","Tissue RNA - cerebellum [nTPM]":"4.0","Tissue RNA - cerebral cortex [nTPM]":"12.1","Tissue RNA - cervix [nTPM]":"5.6","Tissue RNA - choroid plexus [nTPM]":"1.3","Tissue RNA - colon [nTPM]":"6.8","Tissue RNA - duodenum [nTPM]":"2.8","Tissue RNA - endometrium 1 [nTPM]":"4.3","Tissue RNA - epididymis [nTPM]":"2.4","Tissue RNA - esophagus [nTPM]":"3.1","Tissue RNA - fallopian tube [nTPM]":"4.8","Tissue RNA - gallbladder [nTPM]":"7.3","Tissue RNA - heart muscle [nTPM]":"6.6","Tissue RNA - hippocampal formation [nTPM]":"4.2","Tissue RNA - hypothalamus [nTPM]":"3.7","Tissue RNA - kidney [nTPM]":"4.8","Tissue RNA - liver [nTPM]":"8.7","Tissue RNA - lung [nTPM]":"8.7","Tissue RNA - lymph node [nTPM]":"4.1","Tissue RNA - medulla oblongata [nTPM]":"5.8","Tissue RNA - midbrain [nTPM]":"6.1","Tissue RNA - ovary [nTPM]":"4.7","Tissue RNA - pancreas [nTPM]":"3.0","Tissue RNA - parathyroid gland [nTPM]":"2.8","Tissue RNA - pituitary gland [nTPM]":"1.2","Tissue RNA - placenta [nTPM]":"26.6","Tissue RNA - pons [nTPM]":"5.5","Tissue RNA - prostate [nTPM]":"5.2","Tissue RNA - rectum [nTPM]":"5.9","Tissue RNA - retina [nTPM]":"6.1","Tissue RNA - salivary gland [nTPM]":"3.1","Tissue RNA - seminal vesicle [nTPM]":"5.6","Tissue RNA - skeletal muscle [nTPM]":"5.2","Tissue RNA - skin 1 [nTPM]":"4.9","Tissue RNA - small intestine [nTPM]":"3.2","Tissue RNA - smooth muscle [nTPM]":"6.8","Tissue RNA - spinal cord [nTPM]":"1.3","Tissue RNA - spleen [nTPM]":"4.7","Tissue RNA - stomach 1 [nTPM]":"12.0","Tissue RNA - testis [nTPM]":"2.4","Tissue RNA - thalamus [nTPM]":"12.1","Tissue RNA - thymus [nTPM]":"4.4","Tissue RNA - thyroid gland [nTPM]":"3.9","Tissue RNA - tongue [nTPM]":"6.6","Tissue RNA - tonsil [nTPM]":"3.6","Tissue RNA - urinary bladder [nTPM]":"9.4","Tissue RNA - vagina [nTPM]":"3.9","Tissue RNA - white matter [nTPM]":"7.8","Cell RNA - A-431 [nTPM]":"11.5","Cell RNA - A549 [nTPM]":"3.7","Cell RNA - AF22 [nTPM]":"7.5","Cell RNA - AN3-CA [nTPM]":"3.0","Cell RNA - ASC diff [nTPM]":"48.5","Cell RNA - ASC TERT1 [nTPM]":"24.9","Cell RNA - BEWO [nTPM]":"37.5","Cell RNA - BJ [nTPM]":"22.3","Cell RNA - BJ hTERT+ [nTPM]":"7.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.3","Cell RNA - CACO-2 [nTPM]":"19.2","Cell RNA - CAPAN-2 [nTPM]":"11.2","Cell RNA - Daudi [nTPM]":"21.4","Cell RNA - EFO-21 [nTPM]":"5.0","Cell RNA - fHDF\/TERT166 [nTPM]":"15.5","Cell RNA - GAMG [nTPM]":"5.0","Cell RNA - HaCaT [nTPM]":"3.0","Cell RNA - HAP1 [nTPM]":"5.4","Cell RNA - HBEC3-KT [nTPM]":"3.9","Cell RNA - HBF TERT88 [nTPM]":"5.8","Cell RNA - HDLM-2 [nTPM]":"3.3","Cell RNA - HEK 293 [nTPM]":"8.6","Cell RNA - HEL [nTPM]":"1.8","Cell RNA - HeLa [nTPM]":"12.7","Cell RNA - Hep G2 [nTPM]":"5.7","Cell RNA - HHSteC [nTPM]":"2.7","Cell RNA - HL-60 [nTPM]":"3.8","Cell RNA - HMC-1 [nTPM]":"11.5","Cell RNA - HSkMC [nTPM]":"8.3","Cell RNA - hTCEpi [nTPM]":"0.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.8","Cell RNA - hTERT-HME1 [nTPM]":"2.3","Cell RNA - hTERT-RPE1 [nTPM]":"4.0","Cell RNA - HUVEC TERT2 [nTPM]":"8.8","Cell RNA - JURKAT [nTPM]":"2.0","Cell RNA - K-562 [nTPM]":"1.4","Cell RNA - Karpas-707 [nTPM]":"23.5","Cell RNA - LHCN-M2 [nTPM]":"15.2","Cell RNA - MCF7 [nTPM]":"2.9","Cell RNA - MOLT-4 [nTPM]":"2.2","Cell RNA - NB-4 [nTPM]":"3.1","Cell RNA - NTERA-2 [nTPM]":"3.3","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"4.8","Cell RNA - REH [nTPM]":"3.9","Cell RNA - RH-30 [nTPM]":"4.8","Cell RNA - RPMI-8226 [nTPM]":"69.8","Cell RNA - RPTEC TERT1 [nTPM]":"14.2","Cell RNA - RT4 [nTPM]":"16.0","Cell RNA - SCLC-21H [nTPM]":"5.6","Cell RNA - SH-SY5Y [nTPM]":"4.8","Cell RNA - SiHa [nTPM]":"4.7","Cell RNA - SK-BR-3 [nTPM]":"8.3","Cell RNA - SK-MEL-30 [nTPM]":"3.0","Cell RNA - SuSa [nTPM]":"11.8","Cell RNA - T-47d [nTPM]":"3.8","Cell RNA - THP-1 [nTPM]":"1.6","Cell RNA - TIME [nTPM]":"15.8","Cell RNA - U-138 MG [nTPM]":"22.5","Cell RNA - U-2 OS [nTPM]":"2.2","Cell RNA - U-2197 [nTPM]":"30.0","Cell RNA - U-251 MG [nTPM]":"4.4","Cell RNA - U-266\/70 [nTPM]":"110.2","Cell RNA - U-266\/84 [nTPM]":"0.8","Cell RNA - U-698 [nTPM]":"47.2","Cell RNA - U-87 MG [nTPM]":"5.9","Cell RNA - U-937 [nTPM]":"3.0","Cell RNA - WM-115 [nTPM]":"6.5","Blood RNA - basophil [nTPM]":"0.9","Blood RNA - classical monocyte [nTPM]":"1.7","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"2.0","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.9","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"3.7","Brain RNA - basal ganglia [nTPM]":"4.8","Brain RNA - cerebellum [nTPM]":"4.0","Brain RNA - cerebral cortex [nTPM]":"12.1","Brain RNA - hippocampal formation [nTPM]":"4.2","Brain RNA - hypothalamus [nTPM]":"3.7","Brain RNA - medulla oblongata [nTPM]":"5.8","Brain RNA - midbrain [nTPM]":"6.1","Brain RNA - pons [nTPM]":"5.5","Brain RNA - spinal cord [nTPM]":"1.3","Brain RNA - thalamus [nTPM]":"12.1","Brain RNA - white matter [nTPM]":"7.8","Single Cell Type RNA - Adipocytes [nTPM]":"10.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.2","Single Cell Type RNA - Astrocytes [nTPM]":"10.4","Single Cell Type RNA - B-cells [nTPM]":"1.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"3.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"8.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"41.8","Single Cell Type RNA - dendritic cells [nTPM]":"1.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"8.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.5","Single Cell Type RNA - Endothelial cells [nTPM]":"4.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"3.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"32.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.9","Single Cell Type RNA - Fibroblasts [nTPM]":"6.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.2","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"6.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"8.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.7","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"39.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.6","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"7.5","Single Cell Type RNA - Langerhans cells [nTPM]":"1.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.4","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"2.8","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"4.7","Single Cell Type RNA - Muller glia cells [nTPM]":"2.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.2","Single Cell Type RNA - Paneth cells [nTPM]":"6.5","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"1.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"94.0","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"4.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.3","Single Cell Type RNA - Urothelial cells [nTPM]":"8.9"},{"Gene":"STT3A","Gene synonym":["ITM1","MGC9042","STT3-A","TMC"],"Ensembl":"ENSG00000134910","Gene description":"STT3 oligosaccharyltransferase complex catalytic subunit A","Uniprot":["P46977"],"Chromosome":"11","Position":"125591712-125625215","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"391.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"91.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030735"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"23000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA030735":"AB_10603342"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.32e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.57e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.96e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Tissue RNA - adipose tissue [nTPM]":"38.5","Tissue RNA - adrenal gland [nTPM]":"39.2","Tissue RNA - amygdala [nTPM]":"14.6","Tissue RNA - appendix [nTPM]":"44.6","Tissue RNA - basal ganglia [nTPM]":"17.7","Tissue RNA - bone marrow [nTPM]":"31.8","Tissue RNA - breast [nTPM]":"55.8","Tissue RNA - cerebellum [nTPM]":"17.9","Tissue RNA - cerebral cortex [nTPM]":"16.9","Tissue RNA - cervix [nTPM]":"84.9","Tissue RNA - choroid plexus [nTPM]":"29.8","Tissue RNA - colon [nTPM]":"54.0","Tissue RNA - duodenum [nTPM]":"42.2","Tissue RNA - endometrium 1 [nTPM]":"60.8","Tissue RNA - epididymis [nTPM]":"140.4","Tissue RNA - esophagus [nTPM]":"30.2","Tissue RNA - fallopian tube [nTPM]":"56.3","Tissue RNA - gallbladder [nTPM]":"39.5","Tissue RNA - heart muscle [nTPM]":"38.5","Tissue RNA - hippocampal formation [nTPM]":"15.0","Tissue RNA - hypothalamus [nTPM]":"20.1","Tissue RNA - kidney [nTPM]":"45.8","Tissue RNA - liver [nTPM]":"69.0","Tissue RNA - lung [nTPM]":"39.0","Tissue RNA - lymph node [nTPM]":"32.9","Tissue RNA - medulla oblongata [nTPM]":"19.4","Tissue RNA - midbrain [nTPM]":"18.4","Tissue RNA - ovary [nTPM]":"68.0","Tissue RNA - pancreas [nTPM]":"69.0","Tissue RNA - parathyroid gland [nTPM]":"391.8","Tissue RNA - pituitary gland [nTPM]":"29.0","Tissue RNA - placenta [nTPM]":"63.8","Tissue RNA - pons [nTPM]":"19.6","Tissue RNA - prostate [nTPM]":"56.2","Tissue RNA - rectum [nTPM]":"59.5","Tissue RNA - retina [nTPM]":"40.0","Tissue RNA - salivary gland [nTPM]":"80.1","Tissue RNA - seminal vesicle [nTPM]":"77.2","Tissue RNA - skeletal muscle [nTPM]":"18.4","Tissue RNA - skin 1 [nTPM]":"31.6","Tissue RNA - small intestine [nTPM]":"42.1","Tissue RNA - smooth muscle [nTPM]":"58.9","Tissue RNA - spinal cord [nTPM]":"17.5","Tissue RNA - spleen [nTPM]":"34.4","Tissue RNA - stomach 1 [nTPM]":"51.4","Tissue RNA - testis [nTPM]":"44.5","Tissue RNA - thalamus [nTPM]":"17.5","Tissue RNA - thymus [nTPM]":"34.8","Tissue RNA - thyroid gland [nTPM]":"83.9","Tissue RNA - tongue [nTPM]":"24.4","Tissue RNA - tonsil [nTPM]":"48.8","Tissue RNA - urinary bladder [nTPM]":"50.4","Tissue RNA - vagina [nTPM]":"33.3","Tissue RNA - white matter [nTPM]":"23.1","Cell RNA - A-431 [nTPM]":"113.1","Cell RNA - A549 [nTPM]":"99.5","Cell RNA - AF22 [nTPM]":"123.7","Cell RNA - AN3-CA [nTPM]":"173.6","Cell RNA - ASC diff [nTPM]":"230.1","Cell RNA - ASC TERT1 [nTPM]":"176.4","Cell RNA - BEWO [nTPM]":"133.8","Cell RNA - BJ [nTPM]":"198.5","Cell RNA - BJ hTERT+ [nTPM]":"238.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"158.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"196.6","Cell RNA - CACO-2 [nTPM]":"304.2","Cell RNA - CAPAN-2 [nTPM]":"294.3","Cell RNA - Daudi [nTPM]":"143.6","Cell RNA - EFO-21 [nTPM]":"236.2","Cell RNA - fHDF\/TERT166 [nTPM]":"297.3","Cell RNA - GAMG [nTPM]":"222.4","Cell RNA - HaCaT [nTPM]":"202.7","Cell RNA - HAP1 [nTPM]":"173.5","Cell RNA - HBEC3-KT [nTPM]":"176.2","Cell RNA - HBF TERT88 [nTPM]":"208.5","Cell RNA - HDLM-2 [nTPM]":"114.8","Cell RNA - HEK 293 [nTPM]":"90.0","Cell RNA - HEL [nTPM]":"341.0","Cell RNA - HeLa [nTPM]":"63.7","Cell RNA - Hep G2 [nTPM]":"215.1","Cell RNA - HHSteC [nTPM]":"254.4","Cell RNA - HL-60 [nTPM]":"208.4","Cell RNA - HMC-1 [nTPM]":"153.6","Cell RNA - HSkMC [nTPM]":"138.4","Cell RNA - hTCEpi [nTPM]":"125.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"219.5","Cell RNA - hTERT-HME1 [nTPM]":"424.5","Cell RNA - hTERT-RPE1 [nTPM]":"186.1","Cell RNA - HUVEC TERT2 [nTPM]":"182.2","Cell RNA - JURKAT [nTPM]":"63.9","Cell RNA - K-562 [nTPM]":"147.1","Cell RNA - Karpas-707 [nTPM]":"210.6","Cell RNA - LHCN-M2 [nTPM]":"205.4","Cell RNA - MCF7 [nTPM]":"82.7","Cell RNA - MOLT-4 [nTPM]":"84.4","Cell RNA - NB-4 [nTPM]":"65.6","Cell RNA - NTERA-2 [nTPM]":"78.6","Cell RNA - OE19 [nTPM]":"221.8","Cell RNA - PC-3 [nTPM]":"106.0","Cell RNA - REH [nTPM]":"98.9","Cell RNA - RH-30 [nTPM]":"107.1","Cell RNA - RPMI-8226 [nTPM]":"221.5","Cell RNA - RPTEC TERT1 [nTPM]":"173.7","Cell RNA - RT4 [nTPM]":"170.1","Cell RNA - SCLC-21H [nTPM]":"77.5","Cell RNA - SH-SY5Y [nTPM]":"66.2","Cell RNA - SiHa [nTPM]":"142.9","Cell RNA - SK-BR-3 [nTPM]":"229.3","Cell RNA - SK-MEL-30 [nTPM]":"72.5","Cell RNA - SuSa [nTPM]":"144.9","Cell RNA - T-47d [nTPM]":"267.8","Cell RNA - THP-1 [nTPM]":"148.1","Cell RNA - TIME [nTPM]":"164.5","Cell RNA - U-138 MG [nTPM]":"227.7","Cell RNA - U-2 OS [nTPM]":"82.0","Cell RNA - U-2197 [nTPM]":"97.6","Cell RNA - U-251 MG [nTPM]":"159.7","Cell RNA - U-266\/70 [nTPM]":"66.3","Cell RNA - U-266\/84 [nTPM]":"82.4","Cell RNA - U-698 [nTPM]":"109.6","Cell RNA - U-87 MG [nTPM]":"87.4","Cell RNA - U-937 [nTPM]":"206.3","Cell RNA - WM-115 [nTPM]":"184.7","Blood RNA - basophil [nTPM]":"96.2","Blood RNA - classical monocyte [nTPM]":"46.7","Blood RNA - eosinophil [nTPM]":"36.6","Blood RNA - gdT-cell [nTPM]":"56.1","Blood RNA - intermediate monocyte [nTPM]":"45.4","Blood RNA - MAIT T-cell [nTPM]":"77.9","Blood RNA - memory B-cell [nTPM]":"42.8","Blood RNA - memory CD4 T-cell [nTPM]":"53.7","Blood RNA - memory CD8 T-cell [nTPM]":"52.0","Blood RNA - myeloid DC [nTPM]":"65.2","Blood RNA - naive B-cell [nTPM]":"32.1","Blood RNA - naive CD4 T-cell [nTPM]":"37.1","Blood RNA - naive CD8 T-cell [nTPM]":"44.4","Blood RNA - neutrophil [nTPM]":"15.7","Blood RNA - NK-cell [nTPM]":"52.8","Blood RNA - non-classical monocyte [nTPM]":"41.8","Blood RNA - plasmacytoid DC [nTPM]":"158.3","Blood RNA - T-reg [nTPM]":"44.0","Blood RNA - total PBMC [nTPM]":"47.5","Brain RNA - amygdala [nTPM]":"14.6","Brain RNA - basal ganglia [nTPM]":"17.7","Brain RNA - cerebellum [nTPM]":"17.9","Brain RNA - cerebral cortex [nTPM]":"16.9","Brain RNA - hippocampal formation [nTPM]":"15.0","Brain RNA - hypothalamus [nTPM]":"20.1","Brain RNA - medulla oblongata [nTPM]":"19.4","Brain RNA - midbrain [nTPM]":"18.4","Brain RNA - pons [nTPM]":"19.6","Brain RNA - spinal cord [nTPM]":"17.5","Brain RNA - thalamus [nTPM]":"17.5","Brain RNA - white matter [nTPM]":"23.1","Single Cell Type RNA - Adipocytes [nTPM]":"17.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.0","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"20.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"40.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Bipolar cells [nTPM]":"11.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"23.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"29.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"45.4","Single Cell Type RNA - dendritic cells [nTPM]":"21.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"30.1","Single Cell Type RNA - Early spermatids [nTPM]":"10.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"51.0","Single Cell Type RNA - Endothelial cells [nTPM]":"17.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.6","Single Cell Type RNA - Erythroid cells [nTPM]":"19.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"27.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"73.4","Single Cell Type RNA - Fibroblasts [nTPM]":"33.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"26.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"57.0","Single Cell Type RNA - granulocytes [nTPM]":"17.1","Single Cell Type RNA - Granulosa cells [nTPM]":"29.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.2","Single Cell Type RNA - Hepatocytes [nTPM]":"38.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.7","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"37.3","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"23.6","Single Cell Type RNA - Langerhans cells [nTPM]":"31.9","Single Cell Type RNA - Late spermatids [nTPM]":"5.4","Single Cell Type RNA - Leydig cells [nTPM]":"21.5","Single Cell Type RNA - Macrophages [nTPM]":"17.3","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"12.6","Single Cell Type RNA - Muller glia cells [nTPM]":"13.2","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"28.6","Single Cell Type RNA - Paneth cells [nTPM]":"12.2","Single Cell Type RNA - Peritubular cells [nTPM]":"18.8","Single Cell Type RNA - Plasma cells [nTPM]":"91.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.1","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.8","Single Cell Type RNA - Spermatocytes [nTPM]":"33.5","Single Cell Type RNA - Spermatogonia [nTPM]":"13.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"45.6","Single Cell Type RNA - T-cells [nTPM]":"14.6","Single Cell Type RNA - Theca cells [nTPM]":"22.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.9","Single Cell Type RNA - Urothelial cells [nTPM]":"13.9"},{"Gene":"STT3B","Gene synonym":["FLJ90106","SIMP","STT3-B"],"Ensembl":"ENSG00000163527","Gene description":"STT3 oligosaccharyltransferase complex catalytic subunit B","Uniprot":["Q8TCJ2"],"Chromosome":"3","Position":"31532638-31637616","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"264.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036448","HPA036646"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"17000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA036448":"AB_2675129","HPA036646":"AB_10673472"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.91e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Tissue RNA - adipose tissue [nTPM]":"42.8","Tissue RNA - adrenal gland [nTPM]":"59.9","Tissue RNA - amygdala [nTPM]":"21.1","Tissue RNA - appendix [nTPM]":"52.2","Tissue RNA - basal ganglia [nTPM]":"29.5","Tissue RNA - bone marrow [nTPM]":"63.7","Tissue RNA - breast [nTPM]":"57.1","Tissue RNA - cerebellum [nTPM]":"23.3","Tissue RNA - cerebral cortex [nTPM]":"27.0","Tissue RNA - cervix [nTPM]":"62.1","Tissue RNA - choroid plexus [nTPM]":"30.9","Tissue RNA - colon [nTPM]":"59.7","Tissue RNA - duodenum [nTPM]":"47.9","Tissue RNA - endometrium 1 [nTPM]":"51.8","Tissue RNA - epididymis [nTPM]":"90.3","Tissue RNA - esophagus [nTPM]":"44.8","Tissue RNA - fallopian tube [nTPM]":"45.3","Tissue RNA - gallbladder [nTPM]":"60.2","Tissue RNA - heart muscle [nTPM]":"49.4","Tissue RNA - hippocampal formation [nTPM]":"22.6","Tissue RNA - hypothalamus [nTPM]":"30.7","Tissue RNA - kidney [nTPM]":"49.6","Tissue RNA - liver [nTPM]":"74.8","Tissue RNA - lung [nTPM]":"49.3","Tissue RNA - lymph node [nTPM]":"59.9","Tissue RNA - medulla oblongata [nTPM]":"24.3","Tissue RNA - midbrain [nTPM]":"23.1","Tissue RNA - ovary [nTPM]":"105.5","Tissue RNA - pancreas [nTPM]":"45.7","Tissue RNA - parathyroid gland [nTPM]":"76.6","Tissue RNA - pituitary gland [nTPM]":"24.8","Tissue RNA - placenta [nTPM]":"60.3","Tissue RNA - pons [nTPM]":"23.9","Tissue RNA - prostate [nTPM]":"56.3","Tissue RNA - rectum [nTPM]":"61.4","Tissue RNA - retina [nTPM]":"38.6","Tissue RNA - salivary gland [nTPM]":"49.9","Tissue RNA - seminal vesicle [nTPM]":"51.3","Tissue RNA - skeletal muscle [nTPM]":"62.1","Tissue RNA - skin 1 [nTPM]":"44.7","Tissue RNA - small intestine [nTPM]":"49.1","Tissue RNA - smooth muscle [nTPM]":"57.7","Tissue RNA - spinal cord [nTPM]":"25.4","Tissue RNA - spleen [nTPM]":"44.2","Tissue RNA - stomach 1 [nTPM]":"55.1","Tissue RNA - testis [nTPM]":"94.3","Tissue RNA - thalamus [nTPM]":"26.1","Tissue RNA - thymus [nTPM]":"71.8","Tissue RNA - thyroid gland [nTPM]":"80.7","Tissue RNA - tongue [nTPM]":"57.8","Tissue RNA - tonsil [nTPM]":"58.8","Tissue RNA - urinary bladder [nTPM]":"56.6","Tissue RNA - vagina [nTPM]":"32.1","Tissue RNA - white matter [nTPM]":"27.6","Cell RNA - A-431 [nTPM]":"77.9","Cell RNA - A549 [nTPM]":"128.0","Cell RNA - AF22 [nTPM]":"115.4","Cell RNA - AN3-CA [nTPM]":"121.7","Cell RNA - ASC diff [nTPM]":"142.0","Cell RNA - ASC TERT1 [nTPM]":"142.3","Cell RNA - BEWO [nTPM]":"249.7","Cell RNA - BJ [nTPM]":"142.3","Cell RNA - BJ hTERT+ [nTPM]":"124.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"104.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"119.9","Cell RNA - CACO-2 [nTPM]":"117.7","Cell RNA - CAPAN-2 [nTPM]":"164.5","Cell RNA - Daudi [nTPM]":"134.0","Cell RNA - EFO-21 [nTPM]":"67.8","Cell RNA - fHDF\/TERT166 [nTPM]":"130.0","Cell RNA - GAMG [nTPM]":"85.8","Cell RNA - HaCaT [nTPM]":"63.9","Cell RNA - HAP1 [nTPM]":"108.1","Cell RNA - HBEC3-KT [nTPM]":"123.5","Cell RNA - HBF TERT88 [nTPM]":"135.9","Cell RNA - HDLM-2 [nTPM]":"377.1","Cell RNA - HEK 293 [nTPM]":"70.2","Cell RNA - HEL [nTPM]":"115.0","Cell RNA - HeLa [nTPM]":"120.7","Cell RNA - Hep G2 [nTPM]":"126.4","Cell RNA - HHSteC [nTPM]":"109.4","Cell RNA - HL-60 [nTPM]":"252.0","Cell RNA - HMC-1 [nTPM]":"131.1","Cell RNA - HSkMC [nTPM]":"109.8","Cell RNA - hTCEpi [nTPM]":"129.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"148.8","Cell RNA - hTERT-HME1 [nTPM]":"186.7","Cell RNA - hTERT-RPE1 [nTPM]":"160.7","Cell RNA - HUVEC TERT2 [nTPM]":"107.1","Cell RNA - JURKAT [nTPM]":"168.3","Cell RNA - K-562 [nTPM]":"62.8","Cell RNA - Karpas-707 [nTPM]":"209.6","Cell RNA - LHCN-M2 [nTPM]":"144.0","Cell RNA - MCF7 [nTPM]":"44.4","Cell RNA - MOLT-4 [nTPM]":"246.8","Cell RNA - NB-4 [nTPM]":"154.8","Cell RNA - NTERA-2 [nTPM]":"92.9","Cell RNA - OE19 [nTPM]":"129.6","Cell RNA - PC-3 [nTPM]":"70.7","Cell RNA - REH [nTPM]":"252.3","Cell RNA - RH-30 [nTPM]":"62.6","Cell RNA - RPMI-8226 [nTPM]":"196.0","Cell RNA - RPTEC TERT1 [nTPM]":"122.0","Cell RNA - RT4 [nTPM]":"110.7","Cell RNA - SCLC-21H [nTPM]":"48.7","Cell RNA - SH-SY5Y [nTPM]":"59.4","Cell RNA - SiHa [nTPM]":"141.3","Cell RNA - SK-BR-3 [nTPM]":"207.2","Cell RNA - SK-MEL-30 [nTPM]":"84.5","Cell RNA - SuSa [nTPM]":"98.3","Cell RNA - T-47d [nTPM]":"93.4","Cell RNA - THP-1 [nTPM]":"132.8","Cell RNA - TIME [nTPM]":"209.3","Cell RNA - U-138 MG [nTPM]":"139.8","Cell RNA - U-2 OS [nTPM]":"88.6","Cell RNA - U-2197 [nTPM]":"139.7","Cell RNA - U-251 MG [nTPM]":"127.3","Cell RNA - U-266\/70 [nTPM]":"129.0","Cell RNA - U-266\/84 [nTPM]":"166.4","Cell RNA - U-698 [nTPM]":"111.4","Cell RNA - U-87 MG [nTPM]":"126.9","Cell RNA - U-937 [nTPM]":"170.0","Cell RNA - WM-115 [nTPM]":"117.6","Blood RNA - basophil [nTPM]":"2.1","Blood RNA - classical monocyte [nTPM]":"3.3","Blood RNA - eosinophil [nTPM]":"6.2","Blood RNA - gdT-cell [nTPM]":"3.1","Blood RNA - intermediate monocyte [nTPM]":"3.9","Blood RNA - MAIT T-cell [nTPM]":"5.0","Blood RNA - memory B-cell [nTPM]":"2.4","Blood RNA - memory CD4 T-cell [nTPM]":"5.6","Blood RNA - memory CD8 T-cell [nTPM]":"4.4","Blood RNA - myeloid DC [nTPM]":"2.9","Blood RNA - naive B-cell [nTPM]":"2.7","Blood RNA - naive CD4 T-cell [nTPM]":"5.3","Blood RNA - naive CD8 T-cell [nTPM]":"4.3","Blood RNA - neutrophil [nTPM]":"1.2","Blood RNA - NK-cell [nTPM]":"6.1","Blood RNA - non-classical monocyte [nTPM]":"2.9","Blood RNA - plasmacytoid DC [nTPM]":"5.5","Blood RNA - T-reg [nTPM]":"3.0","Blood RNA - total PBMC [nTPM]":"2.0","Brain RNA - amygdala [nTPM]":"21.1","Brain RNA - basal ganglia [nTPM]":"29.5","Brain RNA - cerebellum [nTPM]":"23.3","Brain RNA - cerebral cortex [nTPM]":"27.0","Brain RNA - hippocampal formation [nTPM]":"22.6","Brain RNA - hypothalamus [nTPM]":"30.7","Brain RNA - medulla oblongata [nTPM]":"24.3","Brain RNA - midbrain [nTPM]":"23.1","Brain RNA - pons [nTPM]":"23.9","Brain RNA - spinal cord [nTPM]":"25.4","Brain RNA - thalamus [nTPM]":"26.1","Brain RNA - white matter [nTPM]":"27.6","Single Cell Type RNA - Adipocytes [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"86.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"57.7","Single Cell Type RNA - Astrocytes [nTPM]":"34.6","Single Cell Type RNA - B-cells [nTPM]":"69.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"68.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"58.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"34.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"74.6","Single Cell Type RNA - Bipolar cells [nTPM]":"51.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"57.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"29.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"71.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"54.3","Single Cell Type RNA - Club cells [nTPM]":"76.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"68.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"67.3","Single Cell Type RNA - dendritic cells [nTPM]":"65.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"41.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"34.1","Single Cell Type RNA - Early spermatids [nTPM]":"162.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"65.9","Single Cell Type RNA - Endothelial cells [nTPM]":"42.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"45.1","Single Cell Type RNA - Erythroid cells [nTPM]":"50.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"61.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"45.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"100.5","Single Cell Type RNA - Fibroblasts [nTPM]":"49.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"45.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"43.5","Single Cell Type RNA - granulocytes [nTPM]":"31.1","Single Cell Type RNA - Granulosa cells [nTPM]":"43.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"37.9","Single Cell Type RNA - Hepatocytes [nTPM]":"68.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"54.8","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"59.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"57.5","Single Cell Type RNA - Ionocytes [nTPM]":"36.7","Single Cell Type RNA - Kupffer cells [nTPM]":"58.0","Single Cell Type RNA - Langerhans cells [nTPM]":"76.0","Single Cell Type RNA - Late spermatids [nTPM]":"264.9","Single Cell Type RNA - Leydig cells [nTPM]":"36.4","Single Cell Type RNA - Macrophages [nTPM]":"71.5","Single Cell Type RNA - Melanocytes [nTPM]":"51.6","Single Cell Type RNA - Microglial cells [nTPM]":"53.4","Single Cell Type RNA - monocytes [nTPM]":"49.1","Single Cell Type RNA - Muller glia cells [nTPM]":"34.2","Single Cell Type RNA - NK-cells [nTPM]":"56.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"60.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"73.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"36.5","Single Cell Type RNA - Paneth cells [nTPM]":"50.0","Single Cell Type RNA - Peritubular cells [nTPM]":"32.7","Single Cell Type RNA - Plasma cells [nTPM]":"144.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"74.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"50.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"31.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"42.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"37.4","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"39.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"53.3","Single Cell Type RNA - Spermatocytes [nTPM]":"90.9","Single Cell Type RNA - Spermatogonia [nTPM]":"55.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"65.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"61.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"95.4","Single Cell Type RNA - T-cells [nTPM]":"78.3","Single Cell Type RNA - Theca cells [nTPM]":"68.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"66.1","Single Cell Type RNA - Urothelial cells [nTPM]":"69.4"},{"Gene":"STUB1","Gene synonym":["CHIP","HSPABP2","NY-CO-7","SDCCAG7","UBOX1"],"Ensembl":"ENSG00000103266","Gene description":"STIP1 homology and U-box containing protein 1","Uniprot":["Q9UNE7"],"Chromosome":"16","Position":"680224-682870","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037202","CAB037209","HPA041222","HPA043531"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB037202":"AB_1840759","CAB037209":"AB_1840757","HPA041222":"AB_2677368","HPA043531":"AB_2678533"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.49e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Tissue RNA - adipose tissue [nTPM]":"80.2","Tissue RNA - adrenal gland [nTPM]":"126.3","Tissue RNA - amygdala [nTPM]":"185.5","Tissue RNA - appendix [nTPM]":"35.6","Tissue RNA - basal ganglia [nTPM]":"186.9","Tissue RNA - bone marrow [nTPM]":"48.9","Tissue RNA - breast [nTPM]":"76.0","Tissue RNA - cerebellum [nTPM]":"183.8","Tissue RNA - cerebral cortex [nTPM]":"242.7","Tissue RNA - cervix [nTPM]":"74.8","Tissue RNA - choroid plexus [nTPM]":"173.1","Tissue RNA - colon [nTPM]":"100.3","Tissue RNA - duodenum [nTPM]":"50.7","Tissue RNA - endometrium 1 [nTPM]":"67.0","Tissue RNA - epididymis [nTPM]":"60.3","Tissue RNA - esophagus [nTPM]":"86.8","Tissue RNA - fallopian tube [nTPM]":"65.3","Tissue RNA - gallbladder [nTPM]":"42.1","Tissue RNA - heart muscle [nTPM]":"151.1","Tissue RNA - hippocampal formation [nTPM]":"187.3","Tissue RNA - hypothalamus [nTPM]":"185.3","Tissue RNA - kidney [nTPM]":"91.4","Tissue RNA - liver [nTPM]":"100.7","Tissue RNA - lung [nTPM]":"65.0","Tissue RNA - lymph node [nTPM]":"52.5","Tissue RNA - medulla oblongata [nTPM]":"188.2","Tissue RNA - midbrain [nTPM]":"184.2","Tissue RNA - ovary [nTPM]":"65.7","Tissue RNA - pancreas [nTPM]":"93.7","Tissue RNA - parathyroid gland [nTPM]":"90.6","Tissue RNA - pituitary gland [nTPM]":"93.7","Tissue RNA - placenta [nTPM]":"23.9","Tissue RNA - pons [nTPM]":"187.9","Tissue RNA - prostate [nTPM]":"80.2","Tissue RNA - rectum [nTPM]":"32.6","Tissue RNA - retina [nTPM]":"33.2","Tissue RNA - salivary gland [nTPM]":"86.6","Tissue RNA - seminal vesicle [nTPM]":"53.5","Tissue RNA - skeletal muscle [nTPM]":"201.8","Tissue RNA - skin 1 [nTPM]":"111.7","Tissue RNA - small intestine [nTPM]":"63.1","Tissue RNA - smooth muscle [nTPM]":"40.1","Tissue RNA - spinal cord [nTPM]":"180.6","Tissue RNA - spleen [nTPM]":"70.0","Tissue RNA - stomach 1 [nTPM]":"86.2","Tissue RNA - testis [nTPM]":"45.1","Tissue RNA - thalamus [nTPM]":"193.5","Tissue RNA - thymus [nTPM]":"42.3","Tissue RNA - thyroid gland [nTPM]":"72.9","Tissue RNA - tongue [nTPM]":"125.2","Tissue RNA - tonsil [nTPM]":"38.2","Tissue RNA - urinary bladder [nTPM]":"80.7","Tissue RNA - vagina [nTPM]":"69.1","Tissue RNA - white matter [nTPM]":"188.0","Cell RNA - A-431 [nTPM]":"81.6","Cell RNA - A549 [nTPM]":"107.6","Cell RNA - AF22 [nTPM]":"59.4","Cell RNA - AN3-CA [nTPM]":"108.0","Cell RNA - ASC diff [nTPM]":"123.4","Cell RNA - ASC TERT1 [nTPM]":"102.5","Cell RNA - BEWO [nTPM]":"43.8","Cell RNA - BJ [nTPM]":"112.8","Cell RNA - BJ hTERT+ [nTPM]":"95.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"100.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"90.5","Cell RNA - CACO-2 [nTPM]":"131.0","Cell RNA - CAPAN-2 [nTPM]":"97.1","Cell RNA - Daudi [nTPM]":"83.0","Cell RNA - EFO-21 [nTPM]":"78.2","Cell RNA - fHDF\/TERT166 [nTPM]":"147.5","Cell RNA - GAMG [nTPM]":"69.1","Cell RNA - HaCaT [nTPM]":"69.7","Cell RNA - HAP1 [nTPM]":"73.0","Cell RNA - HBEC3-KT [nTPM]":"137.3","Cell RNA - HBF TERT88 [nTPM]":"42.9","Cell RNA - HDLM-2 [nTPM]":"93.6","Cell RNA - HEK 293 [nTPM]":"318.8","Cell RNA - HEL [nTPM]":"53.4","Cell RNA - HeLa [nTPM]":"154.1","Cell RNA - Hep G2 [nTPM]":"104.7","Cell RNA - HHSteC [nTPM]":"183.7","Cell RNA - HL-60 [nTPM]":"85.9","Cell RNA - HMC-1 [nTPM]":"96.4","Cell RNA - HSkMC [nTPM]":"141.1","Cell RNA - hTCEpi [nTPM]":"134.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"118.2","Cell RNA - hTERT-HME1 [nTPM]":"71.4","Cell RNA - hTERT-RPE1 [nTPM]":"76.3","Cell RNA - HUVEC TERT2 [nTPM]":"106.2","Cell RNA - JURKAT [nTPM]":"72.3","Cell RNA - K-562 [nTPM]":"87.1","Cell RNA - Karpas-707 [nTPM]":"119.2","Cell RNA - LHCN-M2 [nTPM]":"149.3","Cell RNA - MCF7 [nTPM]":"318.4","Cell RNA - MOLT-4 [nTPM]":"90.1","Cell RNA - NB-4 [nTPM]":"85.4","Cell RNA - NTERA-2 [nTPM]":"76.4","Cell RNA - OE19 [nTPM]":"107.1","Cell RNA - PC-3 [nTPM]":"127.5","Cell RNA - REH [nTPM]":"143.5","Cell RNA - RH-30 [nTPM]":"46.8","Cell RNA - RPMI-8226 [nTPM]":"200.6","Cell RNA - RPTEC TERT1 [nTPM]":"132.5","Cell RNA - RT4 [nTPM]":"72.6","Cell RNA - SCLC-21H [nTPM]":"121.1","Cell RNA - SH-SY5Y [nTPM]":"103.4","Cell RNA - SiHa [nTPM]":"89.4","Cell RNA - SK-BR-3 [nTPM]":"165.8","Cell RNA - SK-MEL-30 [nTPM]":"137.1","Cell RNA - SuSa [nTPM]":"35.9","Cell RNA - T-47d [nTPM]":"114.1","Cell RNA - THP-1 [nTPM]":"147.8","Cell RNA - TIME [nTPM]":"108.7","Cell RNA - U-138 MG [nTPM]":"104.3","Cell RNA - U-2 OS [nTPM]":"99.8","Cell RNA - U-2197 [nTPM]":"94.3","Cell RNA - U-251 MG [nTPM]":"125.9","Cell RNA - U-266\/70 [nTPM]":"137.6","Cell RNA - U-266\/84 [nTPM]":"150.2","Cell RNA - U-698 [nTPM]":"132.3","Cell RNA - U-87 MG [nTPM]":"83.8","Cell RNA - U-937 [nTPM]":"73.9","Cell RNA - WM-115 [nTPM]":"122.0","Blood RNA - basophil [nTPM]":"17.7","Blood RNA - classical monocyte [nTPM]":"13.6","Blood RNA - eosinophil [nTPM]":"21.7","Blood RNA - gdT-cell [nTPM]":"15.7","Blood RNA - intermediate monocyte [nTPM]":"12.9","Blood RNA - MAIT T-cell [nTPM]":"14.5","Blood RNA - memory B-cell [nTPM]":"19.6","Blood RNA - memory CD4 T-cell [nTPM]":"13.5","Blood RNA - memory CD8 T-cell [nTPM]":"13.8","Blood RNA - myeloid DC [nTPM]":"12.1","Blood RNA - naive B-cell [nTPM]":"21.0","Blood RNA - naive CD4 T-cell [nTPM]":"12.8","Blood RNA - naive CD8 T-cell [nTPM]":"11.6","Blood RNA - neutrophil [nTPM]":"13.4","Blood RNA - NK-cell [nTPM]":"11.2","Blood RNA - non-classical monocyte [nTPM]":"13.9","Blood RNA - plasmacytoid DC [nTPM]":"20.7","Blood RNA - T-reg [nTPM]":"13.2","Blood RNA - total PBMC [nTPM]":"7.2","Brain RNA - amygdala [nTPM]":"185.5","Brain RNA - basal ganglia [nTPM]":"186.9","Brain RNA - cerebellum [nTPM]":"183.8","Brain RNA - cerebral cortex [nTPM]":"242.7","Brain RNA - hippocampal formation [nTPM]":"187.3","Brain RNA - hypothalamus [nTPM]":"185.3","Brain RNA - medulla oblongata [nTPM]":"188.2","Brain RNA - midbrain [nTPM]":"184.2","Brain RNA - pons [nTPM]":"187.9","Brain RNA - spinal cord [nTPM]":"180.6","Brain RNA - thalamus [nTPM]":"193.5","Brain RNA - white matter [nTPM]":"188.0","Single Cell Type RNA - Adipocytes [nTPM]":"96.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.9","Single Cell Type RNA - Astrocytes [nTPM]":"24.5","Single Cell Type RNA - B-cells [nTPM]":"88.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"114.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"107.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"63.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"83.1","Single Cell Type RNA - Bipolar cells [nTPM]":"93.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"137.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"158.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"104.4","Single Cell Type RNA - Club cells [nTPM]":"52.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"130.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"80.1","Single Cell Type RNA - dendritic cells [nTPM]":"101.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"142.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"285.7","Single Cell Type RNA - Ductal cells [nTPM]":"139.6","Single Cell Type RNA - Early spermatids [nTPM]":"8.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"82.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"69.6","Single Cell Type RNA - Endothelial cells [nTPM]":"71.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"76.0","Single Cell Type RNA - Erythroid cells [nTPM]":"68.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"169.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"93.8","Single Cell Type RNA - Fibroblasts [nTPM]":"85.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"68.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"65.0","Single Cell Type RNA - granulocytes [nTPM]":"21.0","Single Cell Type RNA - Granulosa cells [nTPM]":"97.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"80.3","Single Cell Type RNA - Hepatocytes [nTPM]":"122.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"113.1","Single Cell Type RNA - Horizontal cells [nTPM]":"84.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"101.4","Single Cell Type RNA - Ionocytes [nTPM]":"85.5","Single Cell Type RNA - Kupffer cells [nTPM]":"69.4","Single Cell Type RNA - Langerhans cells [nTPM]":"94.9","Single Cell Type RNA - Late spermatids [nTPM]":"16.7","Single Cell Type RNA - Leydig cells [nTPM]":"109.0","Single Cell Type RNA - Macrophages [nTPM]":"79.0","Single Cell Type RNA - Melanocytes [nTPM]":"117.4","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"154.4","Single Cell Type RNA - Muller glia cells [nTPM]":"184.3","Single Cell Type RNA - NK-cells [nTPM]":"110.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"24.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"190.2","Single Cell Type RNA - Paneth cells [nTPM]":"110.8","Single Cell Type RNA - Peritubular cells [nTPM]":"112.1","Single Cell Type RNA - Plasma cells [nTPM]":"108.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"160.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"165.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"324.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"61.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"83.9","Single Cell Type RNA - Sertoli cells [nTPM]":"72.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"82.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"129.7","Single Cell Type RNA - Spermatocytes [nTPM]":"50.4","Single Cell Type RNA - Spermatogonia [nTPM]":"62.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"107.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"120.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"100.7","Single Cell Type RNA - T-cells [nTPM]":"96.2","Single Cell Type RNA - Theca cells [nTPM]":"132.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"109.3","Single Cell Type RNA - Urothelial cells [nTPM]":"118.8"},{"Gene":"STXBP1","Gene synonym":["hUNC18","MUNC18-1","rbSec1","UNC18"],"Ensembl":"ENSG00000136854","Gene description":"Syntaxin binding protein 1","Uniprot":["P61764"],"Chromosome":"9","Position":"127579370-127696027","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"174.5","pituitary gland":"66.4","retina":"214.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"131.0","Cone photoreceptor cells":"156.4","Excitatory neurons":"243.2","Inhibitory neurons":"157.5","Rod photoreceptor cells":"155.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"39.6"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"174.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SCLC-21H":"144.1","SK-MEL-30":"131.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008209","HPA023483","CAB034434"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"29000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB034434":"AB_2196699","HPA008209":"AB_1857624","HPA023483":"AB_1857625"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.78e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.47e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.73e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.81e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-3"},"Tissue RNA - adipose tissue [nTPM]":"27.5","Tissue RNA - adrenal gland [nTPM]":"28.8","Tissue RNA - amygdala [nTPM]":"22.8","Tissue RNA - appendix [nTPM]":"7.8","Tissue RNA - basal ganglia [nTPM]":"33.2","Tissue RNA - bone marrow [nTPM]":"1.1","Tissue RNA - breast [nTPM]":"21.0","Tissue RNA - cerebellum [nTPM]":"38.6","Tissue RNA - cerebral cortex [nTPM]":"174.5","Tissue RNA - cervix [nTPM]":"21.8","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"15.9","Tissue RNA - duodenum [nTPM]":"5.5","Tissue RNA - endometrium 1 [nTPM]":"24.1","Tissue RNA - epididymis [nTPM]":"7.1","Tissue RNA - esophagus [nTPM]":"10.4","Tissue RNA - fallopian tube [nTPM]":"32.3","Tissue RNA - gallbladder [nTPM]":"11.4","Tissue RNA - heart muscle [nTPM]":"24.0","Tissue RNA - hippocampal formation [nTPM]":"48.3","Tissue RNA - hypothalamus [nTPM]":"12.2","Tissue RNA - kidney [nTPM]":"14.1","Tissue RNA - liver [nTPM]":"3.1","Tissue RNA - lung [nTPM]":"32.1","Tissue RNA - lymph node [nTPM]":"6.0","Tissue RNA - medulla oblongata [nTPM]":"48.7","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"25.2","Tissue RNA - pancreas [nTPM]":"24.8","Tissue RNA - parathyroid gland [nTPM]":"15.0","Tissue RNA - pituitary gland [nTPM]":"66.4","Tissue RNA - placenta [nTPM]":"14.1","Tissue RNA - pons [nTPM]":"33.1","Tissue RNA - prostate [nTPM]":"10.5","Tissue RNA - rectum [nTPM]":"8.4","Tissue RNA - retina [nTPM]":"214.2","Tissue RNA - salivary gland [nTPM]":"15.6","Tissue RNA - seminal vesicle [nTPM]":"10.4","Tissue RNA - skeletal muscle [nTPM]":"9.0","Tissue RNA - skin 1 [nTPM]":"11.4","Tissue RNA - small intestine [nTPM]":"9.3","Tissue RNA - smooth muscle [nTPM]":"21.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"10.4","Tissue RNA - stomach 1 [nTPM]":"13.3","Tissue RNA - testis [nTPM]":"9.1","Tissue RNA - thalamus [nTPM]":"6.8","Tissue RNA - thymus [nTPM]":"5.8","Tissue RNA - thyroid gland [nTPM]":"20.1","Tissue RNA - tongue [nTPM]":"9.2","Tissue RNA - tonsil [nTPM]":"7.0","Tissue RNA - urinary bladder [nTPM]":"15.4","Tissue RNA - vagina [nTPM]":"16.4","Tissue RNA - white matter [nTPM]":"27.2","Cell RNA - A-431 [nTPM]":"13.2","Cell RNA - A549 [nTPM]":"27.1","Cell RNA - AF22 [nTPM]":"25.5","Cell RNA - AN3-CA [nTPM]":"28.8","Cell RNA - ASC diff [nTPM]":"56.6","Cell RNA - ASC TERT1 [nTPM]":"48.3","Cell RNA - BEWO [nTPM]":"23.2","Cell RNA - BJ [nTPM]":"45.0","Cell RNA - BJ hTERT+ [nTPM]":"22.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"26.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.3","Cell RNA - CACO-2 [nTPM]":"1.5","Cell RNA - CAPAN-2 [nTPM]":"15.4","Cell RNA - Daudi [nTPM]":"13.1","Cell RNA - EFO-21 [nTPM]":"24.2","Cell RNA - fHDF\/TERT166 [nTPM]":"29.7","Cell RNA - GAMG [nTPM]":"74.2","Cell RNA - HaCaT [nTPM]":"4.7","Cell RNA - HAP1 [nTPM]":"22.6","Cell RNA - HBEC3-KT [nTPM]":"28.1","Cell RNA - HBF TERT88 [nTPM]":"32.7","Cell RNA - HDLM-2 [nTPM]":"29.8","Cell RNA - HEK 293 [nTPM]":"15.4","Cell RNA - HEL [nTPM]":"17.1","Cell RNA - HeLa [nTPM]":"69.7","Cell RNA - Hep G2 [nTPM]":"4.9","Cell RNA - HHSteC [nTPM]":"28.5","Cell RNA - HL-60 [nTPM]":"1.8","Cell RNA - HMC-1 [nTPM]":"14.6","Cell RNA - HSkMC [nTPM]":"36.6","Cell RNA - hTCEpi [nTPM]":"15.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"70.0","Cell RNA - hTERT-HME1 [nTPM]":"33.7","Cell RNA - hTERT-RPE1 [nTPM]":"42.6","Cell RNA - HUVEC TERT2 [nTPM]":"32.2","Cell RNA - JURKAT [nTPM]":"43.4","Cell RNA - K-562 [nTPM]":"17.8","Cell RNA - Karpas-707 [nTPM]":"19.6","Cell RNA - LHCN-M2 [nTPM]":"45.5","Cell RNA - MCF7 [nTPM]":"24.5","Cell RNA - MOLT-4 [nTPM]":"12.5","Cell RNA - NB-4 [nTPM]":"5.2","Cell RNA - NTERA-2 [nTPM]":"21.5","Cell RNA - OE19 [nTPM]":"21.4","Cell RNA - PC-3 [nTPM]":"35.9","Cell RNA - REH [nTPM]":"7.5","Cell RNA - RH-30 [nTPM]":"12.1","Cell RNA - RPMI-8226 [nTPM]":"31.3","Cell RNA - RPTEC TERT1 [nTPM]":"22.0","Cell RNA - RT4 [nTPM]":"0.6","Cell RNA - SCLC-21H [nTPM]":"144.1","Cell RNA - SH-SY5Y [nTPM]":"69.9","Cell RNA - SiHa [nTPM]":"72.9","Cell RNA - SK-BR-3 [nTPM]":"37.2","Cell RNA - SK-MEL-30 [nTPM]":"131.9","Cell RNA - SuSa [nTPM]":"22.5","Cell RNA - T-47d [nTPM]":"5.8","Cell RNA - THP-1 [nTPM]":"5.6","Cell RNA - TIME [nTPM]":"47.5","Cell RNA - U-138 MG [nTPM]":"30.0","Cell RNA - U-2 OS [nTPM]":"15.1","Cell RNA - U-2197 [nTPM]":"59.9","Cell RNA - U-251 MG [nTPM]":"17.4","Cell RNA - U-266\/70 [nTPM]":"40.2","Cell RNA - U-266\/84 [nTPM]":"73.2","Cell RNA - U-698 [nTPM]":"17.4","Cell RNA - U-87 MG [nTPM]":"59.2","Cell RNA - U-937 [nTPM]":"18.9","Cell RNA - WM-115 [nTPM]":"28.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"22.8","Brain RNA - basal ganglia [nTPM]":"33.2","Brain RNA - cerebellum [nTPM]":"38.6","Brain RNA - cerebral cortex [nTPM]":"174.5","Brain RNA - hippocampal formation [nTPM]":"48.3","Brain RNA - hypothalamus [nTPM]":"12.2","Brain RNA - medulla oblongata [nTPM]":"48.7","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"33.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"6.8","Brain RNA - white matter [nTPM]":"27.2","Single Cell Type RNA - Adipocytes [nTPM]":"24.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"70.7","Single Cell Type RNA - Astrocytes [nTPM]":"34.0","Single Cell Type RNA - B-cells [nTPM]":"1.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Bipolar cells [nTPM]":"131.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"9.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"156.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.7","Single Cell Type RNA - dendritic cells [nTPM]":"1.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"13.1","Single Cell Type RNA - Early spermatids [nTPM]":"2.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.7","Single Cell Type RNA - Endothelial cells [nTPM]":"28.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"45.6","Single Cell Type RNA - Erythroid cells [nTPM]":"4.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"243.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.9","Single Cell Type RNA - Fibroblasts [nTPM]":"18.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.0","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"5.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.7","Single Cell Type RNA - Hepatocytes [nTPM]":"1.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.4","Single Cell Type RNA - Horizontal cells [nTPM]":"84.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"157.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.2","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"2.5","Single Cell Type RNA - Langerhans cells [nTPM]":"5.6","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"20.5","Single Cell Type RNA - Macrophages [nTPM]":"3.0","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"45.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"27.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"61.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"39.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"44.4","Single Cell Type RNA - Plasma cells [nTPM]":"1.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"155.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.2","Single Cell Type RNA - Spermatocytes [nTPM]":"40.6","Single Cell Type RNA - Spermatogonia [nTPM]":"16.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"24.5","Single Cell Type RNA - T-cells [nTPM]":"2.3","Single Cell Type RNA - Theca cells [nTPM]":"17.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.9","Single Cell Type RNA - Urothelial cells [nTPM]":"7.1"},{"Gene":"SUCLA2","Gene synonym":["LINC00444"],"Ensembl":"ENSG00000136143","Gene description":"Succinate-CoA ligase ADP-forming subunit beta","Uniprot":["Q9P2R7"],"Chromosome":"13","Position":"47745736-48037968","Protein class":["Citric acid cycle related proteins","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Tricarboxylic acid cycle"],"Molecular function":["Ligase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"232.2","tongue":"271.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"256.2","Late spermatids":"314.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039435","HPA039536","HPA061528"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA039435":"AB_10673144","HPA039536":"AB_2676561","HPA061528":"AB_2684553"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.59e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.22e-4"},"Tissue RNA - adipose tissue [nTPM]":"53.9","Tissue RNA - adrenal gland [nTPM]":"40.6","Tissue RNA - amygdala [nTPM]":"28.4","Tissue RNA - appendix [nTPM]":"20.2","Tissue RNA - basal ganglia [nTPM]":"30.8","Tissue RNA - bone marrow [nTPM]":"13.6","Tissue RNA - breast [nTPM]":"38.7","Tissue RNA - cerebellum [nTPM]":"36.6","Tissue RNA - cerebral cortex [nTPM]":"39.2","Tissue RNA - cervix [nTPM]":"32.4","Tissue RNA - choroid plexus [nTPM]":"33.6","Tissue RNA - colon [nTPM]":"37.1","Tissue RNA - duodenum [nTPM]":"58.2","Tissue RNA - endometrium 1 [nTPM]":"27.2","Tissue RNA - epididymis [nTPM]":"24.8","Tissue RNA - esophagus [nTPM]":"33.1","Tissue RNA - fallopian tube [nTPM]":"24.7","Tissue RNA - gallbladder [nTPM]":"20.3","Tissue RNA - heart muscle [nTPM]":"100.2","Tissue RNA - hippocampal formation [nTPM]":"30.7","Tissue RNA - hypothalamus [nTPM]":"38.2","Tissue RNA - kidney [nTPM]":"77.5","Tissue RNA - liver [nTPM]":"29.0","Tissue RNA - lung [nTPM]":"18.2","Tissue RNA - lymph node [nTPM]":"22.0","Tissue RNA - medulla oblongata [nTPM]":"30.6","Tissue RNA - midbrain [nTPM]":"30.0","Tissue RNA - ovary [nTPM]":"30.9","Tissue RNA - pancreas [nTPM]":"25.4","Tissue RNA - parathyroid gland [nTPM]":"71.2","Tissue RNA - pituitary gland [nTPM]":"20.4","Tissue RNA - placenta [nTPM]":"28.1","Tissue RNA - pons [nTPM]":"32.3","Tissue RNA - prostate [nTPM]":"35.8","Tissue RNA - rectum [nTPM]":"36.3","Tissue RNA - retina [nTPM]":"44.2","Tissue RNA - salivary gland [nTPM]":"33.9","Tissue RNA - seminal vesicle [nTPM]":"31.3","Tissue RNA - skeletal muscle [nTPM]":"232.2","Tissue RNA - skin 1 [nTPM]":"20.5","Tissue RNA - small intestine [nTPM]":"44.7","Tissue RNA - smooth muscle [nTPM]":"33.1","Tissue RNA - spinal cord [nTPM]":"30.6","Tissue RNA - spleen [nTPM]":"19.9","Tissue RNA - stomach 1 [nTPM]":"29.7","Tissue RNA - testis [nTPM]":"17.9","Tissue RNA - thalamus [nTPM]":"33.8","Tissue RNA - thymus [nTPM]":"30.7","Tissue RNA - thyroid gland [nTPM]":"36.4","Tissue RNA - tongue [nTPM]":"271.9","Tissue RNA - tonsil [nTPM]":"23.9","Tissue RNA - urinary bladder [nTPM]":"26.0","Tissue RNA - vagina [nTPM]":"25.3","Tissue RNA - white matter [nTPM]":"35.1","Cell RNA - A-431 [nTPM]":"44.9","Cell RNA - A549 [nTPM]":"49.5","Cell RNA - AF22 [nTPM]":"60.6","Cell RNA - AN3-CA [nTPM]":"37.1","Cell RNA - ASC diff [nTPM]":"68.4","Cell RNA - ASC TERT1 [nTPM]":"51.3","Cell RNA - BEWO [nTPM]":"38.9","Cell RNA - BJ [nTPM]":"64.8","Cell RNA - BJ hTERT+ [nTPM]":"72.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"66.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"44.5","Cell RNA - CACO-2 [nTPM]":"91.3","Cell RNA - CAPAN-2 [nTPM]":"47.9","Cell RNA - Daudi [nTPM]":"61.3","Cell RNA - EFO-21 [nTPM]":"49.3","Cell RNA - fHDF\/TERT166 [nTPM]":"63.9","Cell RNA - GAMG [nTPM]":"39.9","Cell RNA - HaCaT [nTPM]":"60.0","Cell RNA - HAP1 [nTPM]":"81.9","Cell RNA - HBEC3-KT [nTPM]":"61.9","Cell RNA - HBF TERT88 [nTPM]":"81.6","Cell RNA - HDLM-2 [nTPM]":"59.8","Cell RNA - HEK 293 [nTPM]":"75.9","Cell RNA - HEL [nTPM]":"69.2","Cell RNA - HeLa [nTPM]":"45.8","Cell RNA - Hep G2 [nTPM]":"58.0","Cell RNA - HHSteC [nTPM]":"47.6","Cell RNA - HL-60 [nTPM]":"69.9","Cell RNA - HMC-1 [nTPM]":"38.9","Cell RNA - HSkMC [nTPM]":"48.4","Cell RNA - hTCEpi [nTPM]":"71.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"45.3","Cell RNA - hTERT-HME1 [nTPM]":"52.6","Cell RNA - hTERT-RPE1 [nTPM]":"54.4","Cell RNA - HUVEC TERT2 [nTPM]":"49.0","Cell RNA - JURKAT [nTPM]":"70.7","Cell RNA - K-562 [nTPM]":"47.7","Cell RNA - Karpas-707 [nTPM]":"21.1","Cell RNA - LHCN-M2 [nTPM]":"65.8","Cell RNA - MCF7 [nTPM]":"31.4","Cell RNA - MOLT-4 [nTPM]":"73.1","Cell RNA - NB-4 [nTPM]":"80.8","Cell RNA - NTERA-2 [nTPM]":"64.4","Cell RNA - OE19 [nTPM]":"150.2","Cell RNA - PC-3 [nTPM]":"64.7","Cell RNA - REH [nTPM]":"60.9","Cell RNA - RH-30 [nTPM]":"55.4","Cell RNA - RPMI-8226 [nTPM]":"49.3","Cell RNA - RPTEC TERT1 [nTPM]":"94.4","Cell RNA - RT4 [nTPM]":"41.9","Cell RNA - SCLC-21H [nTPM]":"34.7","Cell RNA - SH-SY5Y [nTPM]":"41.2","Cell RNA - SiHa [nTPM]":"54.5","Cell RNA - SK-BR-3 [nTPM]":"49.3","Cell RNA - SK-MEL-30 [nTPM]":"39.1","Cell RNA - SuSa [nTPM]":"66.5","Cell RNA - T-47d [nTPM]":"43.8","Cell RNA - THP-1 [nTPM]":"60.8","Cell RNA - TIME [nTPM]":"39.0","Cell RNA - U-138 MG [nTPM]":"36.2","Cell RNA - U-2 OS [nTPM]":"24.1","Cell RNA - U-2197 [nTPM]":"53.0","Cell RNA - U-251 MG [nTPM]":"45.7","Cell RNA - U-266\/70 [nTPM]":"23.0","Cell RNA - U-266\/84 [nTPM]":"37.4","Cell RNA - U-698 [nTPM]":"72.7","Cell RNA - U-87 MG [nTPM]":"22.8","Cell RNA - U-937 [nTPM]":"50.9","Cell RNA - WM-115 [nTPM]":"54.8","Blood RNA - basophil [nTPM]":"12.6","Blood RNA - classical monocyte [nTPM]":"50.2","Blood RNA - eosinophil [nTPM]":"27.8","Blood RNA - gdT-cell [nTPM]":"34.4","Blood RNA - intermediate monocyte [nTPM]":"53.7","Blood RNA - MAIT T-cell [nTPM]":"41.9","Blood RNA - memory B-cell [nTPM]":"34.6","Blood RNA - memory CD4 T-cell [nTPM]":"38.0","Blood RNA - memory CD8 T-cell [nTPM]":"42.2","Blood RNA - myeloid DC [nTPM]":"62.5","Blood RNA - naive B-cell [nTPM]":"33.1","Blood RNA - naive CD4 T-cell [nTPM]":"47.7","Blood RNA - naive CD8 T-cell [nTPM]":"47.5","Blood RNA - neutrophil [nTPM]":"8.8","Blood RNA - NK-cell [nTPM]":"51.8","Blood RNA - non-classical monocyte [nTPM]":"46.1","Blood RNA - plasmacytoid DC [nTPM]":"49.8","Blood RNA - T-reg [nTPM]":"46.6","Blood RNA - total PBMC [nTPM]":"36.5","Brain RNA - amygdala [nTPM]":"28.4","Brain RNA - basal ganglia [nTPM]":"30.8","Brain RNA - cerebellum [nTPM]":"36.6","Brain RNA - cerebral cortex [nTPM]":"39.2","Brain RNA - hippocampal formation [nTPM]":"30.7","Brain RNA - hypothalamus [nTPM]":"38.2","Brain RNA - medulla oblongata [nTPM]":"30.6","Brain RNA - midbrain [nTPM]":"30.0","Brain RNA - pons [nTPM]":"32.3","Brain RNA - spinal cord [nTPM]":"30.6","Brain RNA - thalamus [nTPM]":"33.8","Brain RNA - white matter [nTPM]":"35.1","Single Cell Type RNA - Adipocytes [nTPM]":"20.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.8","Single Cell Type RNA - Astrocytes [nTPM]":"17.6","Single Cell Type RNA - B-cells [nTPM]":"20.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"32.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"37.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"57.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.1","Single Cell Type RNA - Bipolar cells [nTPM]":"44.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"28.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"26.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"148.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"40.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"48.7","Single Cell Type RNA - dendritic cells [nTPM]":"18.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"29.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"164.4","Single Cell Type RNA - Ductal cells [nTPM]":"32.3","Single Cell Type RNA - Early spermatids [nTPM]":"256.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"50.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"32.0","Single Cell Type RNA - Endothelial cells [nTPM]":"22.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.2","Single Cell Type RNA - Erythroid cells [nTPM]":"21.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"37.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"42.7","Single Cell Type RNA - Fibroblasts [nTPM]":"37.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"52.6","Single Cell Type RNA - granulocytes [nTPM]":"33.7","Single Cell Type RNA - Granulosa cells [nTPM]":"25.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.1","Single Cell Type RNA - Hepatocytes [nTPM]":"14.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"29.9","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"39.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.5","Single Cell Type RNA - Ionocytes [nTPM]":"71.2","Single Cell Type RNA - Kupffer cells [nTPM]":"16.7","Single Cell Type RNA - Langerhans cells [nTPM]":"20.4","Single Cell Type RNA - Late spermatids [nTPM]":"314.2","Single Cell Type RNA - Leydig cells [nTPM]":"37.0","Single Cell Type RNA - Macrophages [nTPM]":"21.7","Single Cell Type RNA - Melanocytes [nTPM]":"42.7","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"24.9","Single Cell Type RNA - Muller glia cells [nTPM]":"43.3","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"26.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"38.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.2","Single Cell Type RNA - Paneth cells [nTPM]":"30.6","Single Cell Type RNA - Peritubular cells [nTPM]":"46.3","Single Cell Type RNA - Plasma cells [nTPM]":"22.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"35.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"62.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"127.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"42.4","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"33.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"50.0","Single Cell Type RNA - Spermatocytes [nTPM]":"36.3","Single Cell Type RNA - Spermatogonia [nTPM]":"29.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"31.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"52.1","Single Cell Type RNA - T-cells [nTPM]":"19.7","Single Cell Type RNA - Theca cells [nTPM]":"47.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"30.4","Single Cell Type RNA - Urothelial cells [nTPM]":"39.0"},{"Gene":"SUCLG1","Gene synonym":[],"Ensembl":"ENSG00000163541","Gene description":"Succinate-CoA ligase GDP\/ADP-forming subunit alpha","Uniprot":["P53597"],"Chromosome":"2","Position":"84423528-84460045","Protein class":["Citric acid cycle related proteins","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Tricarboxylic acid cycle"],"Molecular function":["Ligase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"554.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"935.2","Proximal enterocytes":"647.5","Proximal tubular cells":"2949.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036683","HPA036684"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Mitochondria","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"350000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Plasma membrane","Cytosol"],"Antibody RRID":{"HPA036683":"AB_10671708","HPA036684":"AB_2675248"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.16e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.23e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.21e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Tissue RNA - adipose tissue [nTPM]":"118.7","Tissue RNA - adrenal gland [nTPM]":"73.3","Tissue RNA - amygdala [nTPM]":"70.6","Tissue RNA - appendix [nTPM]":"43.1","Tissue RNA - basal ganglia [nTPM]":"73.2","Tissue RNA - bone marrow [nTPM]":"48.2","Tissue RNA - breast [nTPM]":"80.0","Tissue RNA - cerebellum [nTPM]":"76.2","Tissue RNA - cerebral cortex [nTPM]":"92.5","Tissue RNA - cervix [nTPM]":"49.9","Tissue RNA - choroid plexus [nTPM]":"91.1","Tissue RNA - colon [nTPM]":"156.9","Tissue RNA - duodenum [nTPM]":"231.1","Tissue RNA - endometrium 1 [nTPM]":"42.4","Tissue RNA - epididymis [nTPM]":"78.8","Tissue RNA - esophagus [nTPM]":"86.9","Tissue RNA - fallopian tube [nTPM]":"54.6","Tissue RNA - gallbladder [nTPM]":"41.9","Tissue RNA - heart muscle [nTPM]":"258.1","Tissue RNA - hippocampal formation [nTPM]":"71.1","Tissue RNA - hypothalamus [nTPM]":"74.5","Tissue RNA - kidney [nTPM]":"554.0","Tissue RNA - liver [nTPM]":"193.0","Tissue RNA - lung [nTPM]":"41.6","Tissue RNA - lymph node [nTPM]":"47.8","Tissue RNA - medulla oblongata [nTPM]":"71.7","Tissue RNA - midbrain [nTPM]":"70.2","Tissue RNA - ovary [nTPM]":"45.7","Tissue RNA - pancreas [nTPM]":"93.6","Tissue RNA - parathyroid gland [nTPM]":"244.2","Tissue RNA - pituitary gland [nTPM]":"46.8","Tissue RNA - placenta [nTPM]":"48.8","Tissue RNA - pons [nTPM]":"72.9","Tissue RNA - prostate [nTPM]":"54.3","Tissue RNA - rectum [nTPM]":"165.9","Tissue RNA - retina [nTPM]":"38.4","Tissue RNA - salivary gland [nTPM]":"120.6","Tissue RNA - seminal vesicle [nTPM]":"66.6","Tissue RNA - skeletal muscle [nTPM]":"274.1","Tissue RNA - skin 1 [nTPM]":"55.4","Tissue RNA - small intestine [nTPM]":"195.4","Tissue RNA - smooth muscle [nTPM]":"63.5","Tissue RNA - spinal cord [nTPM]":"73.8","Tissue RNA - spleen [nTPM]":"39.6","Tissue RNA - stomach 1 [nTPM]":"81.1","Tissue RNA - testis [nTPM]":"36.9","Tissue RNA - thalamus [nTPM]":"73.3","Tissue RNA - thymus [nTPM]":"61.7","Tissue RNA - thyroid gland [nTPM]":"97.6","Tissue RNA - tongue [nTPM]":"368.1","Tissue RNA - tonsil [nTPM]":"63.1","Tissue RNA - urinary bladder [nTPM]":"66.4","Tissue RNA - vagina [nTPM]":"58.5","Tissue RNA - white matter [nTPM]":"76.9","Cell RNA - A-431 [nTPM]":"90.2","Cell RNA - A549 [nTPM]":"94.9","Cell RNA - AF22 [nTPM]":"73.8","Cell RNA - AN3-CA [nTPM]":"91.1","Cell RNA - ASC diff [nTPM]":"137.8","Cell RNA - ASC TERT1 [nTPM]":"91.2","Cell RNA - BEWO [nTPM]":"127.7","Cell RNA - BJ [nTPM]":"98.4","Cell RNA - BJ hTERT+ [nTPM]":"85.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"126.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"91.2","Cell RNA - CACO-2 [nTPM]":"224.5","Cell RNA - CAPAN-2 [nTPM]":"72.0","Cell RNA - Daudi [nTPM]":"122.4","Cell RNA - EFO-21 [nTPM]":"67.0","Cell RNA - fHDF\/TERT166 [nTPM]":"119.8","Cell RNA - GAMG [nTPM]":"100.2","Cell RNA - HaCaT [nTPM]":"126.8","Cell RNA - HAP1 [nTPM]":"156.7","Cell RNA - HBEC3-KT [nTPM]":"118.4","Cell RNA - HBF TERT88 [nTPM]":"149.8","Cell RNA - HDLM-2 [nTPM]":"119.3","Cell RNA - HEK 293 [nTPM]":"141.4","Cell RNA - HEL [nTPM]":"105.9","Cell RNA - HeLa [nTPM]":"75.4","Cell RNA - Hep G2 [nTPM]":"129.2","Cell RNA - HHSteC [nTPM]":"116.0","Cell RNA - HL-60 [nTPM]":"110.6","Cell RNA - HMC-1 [nTPM]":"82.7","Cell RNA - HSkMC [nTPM]":"109.1","Cell RNA - hTCEpi [nTPM]":"95.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"106.3","Cell RNA - hTERT-HME1 [nTPM]":"143.7","Cell RNA - hTERT-RPE1 [nTPM]":"76.7","Cell RNA - HUVEC TERT2 [nTPM]":"115.1","Cell RNA - JURKAT [nTPM]":"97.9","Cell RNA - K-562 [nTPM]":"110.1","Cell RNA - Karpas-707 [nTPM]":"98.1","Cell RNA - LHCN-M2 [nTPM]":"117.5","Cell RNA - MCF7 [nTPM]":"137.4","Cell RNA - MOLT-4 [nTPM]":"158.2","Cell RNA - NB-4 [nTPM]":"101.1","Cell RNA - NTERA-2 [nTPM]":"39.4","Cell RNA - OE19 [nTPM]":"334.1","Cell RNA - PC-3 [nTPM]":"170.0","Cell RNA - REH [nTPM]":"98.3","Cell RNA - RH-30 [nTPM]":"172.6","Cell RNA - RPMI-8226 [nTPM]":"134.5","Cell RNA - RPTEC TERT1 [nTPM]":"172.2","Cell RNA - RT4 [nTPM]":"106.4","Cell RNA - SCLC-21H [nTPM]":"89.8","Cell RNA - SH-SY5Y [nTPM]":"49.3","Cell RNA - SiHa [nTPM]":"78.9","Cell RNA - SK-BR-3 [nTPM]":"163.7","Cell RNA - SK-MEL-30 [nTPM]":"162.3","Cell RNA - SuSa [nTPM]":"69.0","Cell RNA - T-47d [nTPM]":"99.8","Cell RNA - THP-1 [nTPM]":"85.4","Cell RNA - TIME [nTPM]":"93.1","Cell RNA - U-138 MG [nTPM]":"96.6","Cell RNA - U-2 OS [nTPM]":"94.6","Cell RNA - U-2197 [nTPM]":"119.9","Cell RNA - U-251 MG [nTPM]":"124.9","Cell RNA - U-266\/70 [nTPM]":"84.2","Cell RNA - U-266\/84 [nTPM]":"131.0","Cell RNA - U-698 [nTPM]":"107.8","Cell RNA - U-87 MG [nTPM]":"113.9","Cell RNA - U-937 [nTPM]":"150.4","Cell RNA - WM-115 [nTPM]":"88.0","Blood RNA - basophil [nTPM]":"101.6","Blood RNA - classical monocyte [nTPM]":"91.0","Blood RNA - eosinophil [nTPM]":"80.8","Blood RNA - gdT-cell [nTPM]":"79.0","Blood RNA - intermediate monocyte [nTPM]":"110.2","Blood RNA - MAIT T-cell [nTPM]":"88.5","Blood RNA - memory B-cell [nTPM]":"70.2","Blood RNA - memory CD4 T-cell [nTPM]":"72.0","Blood RNA - memory CD8 T-cell [nTPM]":"88.4","Blood RNA - myeloid DC [nTPM]":"115.4","Blood RNA - naive B-cell [nTPM]":"55.4","Blood RNA - naive CD4 T-cell [nTPM]":"79.1","Blood RNA - naive CD8 T-cell [nTPM]":"84.3","Blood RNA - neutrophil [nTPM]":"49.7","Blood RNA - NK-cell [nTPM]":"102.3","Blood RNA - non-classical monocyte [nTPM]":"114.3","Blood RNA - plasmacytoid DC [nTPM]":"63.2","Blood RNA - T-reg [nTPM]":"107.7","Blood RNA - total PBMC [nTPM]":"142.7","Brain RNA - amygdala [nTPM]":"70.6","Brain RNA - basal ganglia [nTPM]":"73.2","Brain RNA - cerebellum [nTPM]":"76.2","Brain RNA - cerebral cortex [nTPM]":"92.5","Brain RNA - hippocampal formation [nTPM]":"71.1","Brain RNA - hypothalamus [nTPM]":"74.5","Brain RNA - medulla oblongata [nTPM]":"71.7","Brain RNA - midbrain [nTPM]":"70.2","Brain RNA - pons [nTPM]":"72.9","Brain RNA - spinal cord [nTPM]":"73.8","Brain RNA - thalamus [nTPM]":"73.3","Brain RNA - white matter [nTPM]":"76.9","Single Cell Type RNA - Adipocytes [nTPM]":"52.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"64.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"96.5","Single Cell Type RNA - Astrocytes [nTPM]":"32.7","Single Cell Type RNA - B-cells [nTPM]":"61.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"35.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"108.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"129.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"44.3","Single Cell Type RNA - Bipolar cells [nTPM]":"33.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"105.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"109.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"408.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"131.5","Single Cell Type RNA - Club cells [nTPM]":"115.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"141.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"232.3","Single Cell Type RNA - dendritic cells [nTPM]":"49.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"218.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"935.2","Single Cell Type RNA - Ductal cells [nTPM]":"131.8","Single Cell Type RNA - Early spermatids [nTPM]":"49.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"67.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"56.9","Single Cell Type RNA - Endothelial cells [nTPM]":"57.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"106.3","Single Cell Type RNA - Erythroid cells [nTPM]":"68.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"45.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"113.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"129.3","Single Cell Type RNA - Fibroblasts [nTPM]":"69.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"79.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"80.8","Single Cell Type RNA - granulocytes [nTPM]":"91.3","Single Cell Type RNA - Granulosa cells [nTPM]":"46.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"57.5","Single Cell Type RNA - Hepatocytes [nTPM]":"210.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"131.7","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"43.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"202.1","Single Cell Type RNA - Ionocytes [nTPM]":"105.8","Single Cell Type RNA - Kupffer cells [nTPM]":"71.3","Single Cell Type RNA - Langerhans cells [nTPM]":"46.0","Single Cell Type RNA - Late spermatids [nTPM]":"35.9","Single Cell Type RNA - Leydig cells [nTPM]":"54.7","Single Cell Type RNA - Macrophages [nTPM]":"82.2","Single Cell Type RNA - Melanocytes [nTPM]":"119.2","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"89.8","Single Cell Type RNA - Muller glia cells [nTPM]":"68.2","Single Cell Type RNA - NK-cells [nTPM]":"58.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"28.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"46.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"67.1","Single Cell Type RNA - Paneth cells [nTPM]":"215.4","Single Cell Type RNA - Peritubular cells [nTPM]":"74.1","Single Cell Type RNA - Plasma cells [nTPM]":"57.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"64.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"647.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2949.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"83.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"36.1","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"61.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"98.3","Single Cell Type RNA - Spermatocytes [nTPM]":"138.9","Single Cell Type RNA - Spermatogonia [nTPM]":"54.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"111.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"41.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"188.4","Single Cell Type RNA - T-cells [nTPM]":"64.4","Single Cell Type RNA - Theca cells [nTPM]":"90.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"388.7","Single Cell Type RNA - Urothelial cells [nTPM]":"111.0"},{"Gene":"SUGCT","Gene synonym":["C7orf10","DERP13","FLJ11808","ORF19"],"Ensembl":"ENSG00000175600","Gene description":"Succinyl-CoA:glutarate-CoA transferase","Uniprot":["Q9HAC7"],"Chromosome":"7","Position":"40135005-40860763","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Glutaricaciduria"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"44.4","liver":"28.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"76.0","Inhibitory neurons":"38.5","Oligodendrocyte precursor cells":"58.3","Proximal tubular cells":"81.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"1.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HBEC3-KT":"43.9","LHCN-M2":"26.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026698","HPA026704","HPA026705"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026698":"AB_10600191","HPA026704":"AB_10600230","HPA026705":"AB_10601003"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.93e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.53e-4"},"Tissue RNA - adipose tissue [nTPM]":"2.4","Tissue RNA - adrenal gland [nTPM]":"9.0","Tissue RNA - amygdala [nTPM]":"1.7","Tissue RNA - appendix [nTPM]":"0.9","Tissue RNA - basal ganglia [nTPM]":"1.8","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"2.3","Tissue RNA - cerebellum [nTPM]":"1.7","Tissue RNA - cerebral cortex [nTPM]":"2.2","Tissue RNA - cervix [nTPM]":"2.2","Tissue RNA - choroid plexus [nTPM]":"4.4","Tissue RNA - colon [nTPM]":"4.5","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"2.2","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"2.1","Tissue RNA - fallopian tube [nTPM]":"1.7","Tissue RNA - gallbladder [nTPM]":"2.8","Tissue RNA - heart muscle [nTPM]":"3.9","Tissue RNA - hippocampal formation [nTPM]":"1.7","Tissue RNA - hypothalamus [nTPM]":"2.0","Tissue RNA - kidney [nTPM]":"44.4","Tissue RNA - liver [nTPM]":"28.4","Tissue RNA - lung [nTPM]":"0.6","Tissue RNA - lymph node [nTPM]":"0.8","Tissue RNA - medulla oblongata [nTPM]":"2.0","Tissue RNA - midbrain [nTPM]":"2.1","Tissue RNA - ovary [nTPM]":"4.1","Tissue RNA - pancreas [nTPM]":"2.3","Tissue RNA - parathyroid gland [nTPM]":"4.1","Tissue RNA - pituitary gland [nTPM]":"0.9","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"1.9","Tissue RNA - prostate [nTPM]":"2.0","Tissue RNA - rectum [nTPM]":"2.4","Tissue RNA - retina [nTPM]":"2.0","Tissue RNA - salivary gland [nTPM]":"1.4","Tissue RNA - seminal vesicle [nTPM]":"1.8","Tissue RNA - skeletal muscle [nTPM]":"10.3","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"5.3","Tissue RNA - smooth muscle [nTPM]":"2.2","Tissue RNA - spinal cord [nTPM]":"1.8","Tissue RNA - spleen [nTPM]":"0.8","Tissue RNA - stomach 1 [nTPM]":"1.0","Tissue RNA - testis [nTPM]":"2.8","Tissue RNA - thalamus [nTPM]":"1.8","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"1.8","Tissue RNA - tongue [nTPM]":"8.2","Tissue RNA - tonsil [nTPM]":"1.0","Tissue RNA - urinary bladder [nTPM]":"2.0","Tissue RNA - vagina [nTPM]":"1.6","Tissue RNA - white matter [nTPM]":"1.8","Cell RNA - A-431 [nTPM]":"0.8","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"4.8","Cell RNA - AN3-CA [nTPM]":"3.4","Cell RNA - ASC diff [nTPM]":"5.0","Cell RNA - ASC TERT1 [nTPM]":"11.5","Cell RNA - BEWO [nTPM]":"1.8","Cell RNA - BJ [nTPM]":"2.5","Cell RNA - BJ hTERT+ [nTPM]":"4.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.8","Cell RNA - CACO-2 [nTPM]":"2.0","Cell RNA - CAPAN-2 [nTPM]":"1.0","Cell RNA - Daudi [nTPM]":"3.1","Cell RNA - EFO-21 [nTPM]":"1.2","Cell RNA - fHDF\/TERT166 [nTPM]":"3.5","Cell RNA - GAMG [nTPM]":"3.4","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"1.4","Cell RNA - HBEC3-KT [nTPM]":"43.9","Cell RNA - HBF TERT88 [nTPM]":"5.3","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"2.1","Cell RNA - HEL [nTPM]":"2.8","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"7.3","Cell RNA - HHSteC [nTPM]":"6.2","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"14.6","Cell RNA - hTCEpi [nTPM]":"9.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.7","Cell RNA - hTERT-HME1 [nTPM]":"2.2","Cell RNA - hTERT-RPE1 [nTPM]":"6.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.9","Cell RNA - JURKAT [nTPM]":"1.2","Cell RNA - K-562 [nTPM]":"3.9","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"26.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"8.1","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"3.7","Cell RNA - REH [nTPM]":"2.9","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"7.4","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"2.7","Cell RNA - SiHa [nTPM]":"4.0","Cell RNA - SK-BR-3 [nTPM]":"1.8","Cell RNA - SK-MEL-30 [nTPM]":"5.8","Cell RNA - SuSa [nTPM]":"7.9","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.7","Cell RNA - TIME [nTPM]":"3.7","Cell RNA - U-138 MG [nTPM]":"14.6","Cell RNA - U-2 OS [nTPM]":"4.2","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"1.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"2.8","Cell RNA - U-937 [nTPM]":"1.2","Cell RNA - WM-115 [nTPM]":"3.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.7","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"1.7","Brain RNA - basal ganglia [nTPM]":"1.8","Brain RNA - cerebellum [nTPM]":"1.7","Brain RNA - cerebral cortex [nTPM]":"2.2","Brain RNA - hippocampal formation [nTPM]":"1.7","Brain RNA - hypothalamus [nTPM]":"2.0","Brain RNA - medulla oblongata [nTPM]":"2.0","Brain RNA - midbrain [nTPM]":"2.1","Brain RNA - pons [nTPM]":"1.9","Brain RNA - spinal cord [nTPM]":"1.8","Brain RNA - thalamus [nTPM]":"1.8","Brain RNA - white matter [nTPM]":"1.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"76.0","Single Cell Type RNA - B-cells [nTPM]":"1.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"26.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"1.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"4.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"1.2","Single Cell Type RNA - Early spermatids [nTPM]":"31.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.5","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.4","Single Cell Type RNA - Fibroblasts [nTPM]":"3.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"21.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"38.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1.0","Single Cell Type RNA - Late spermatids [nTPM]":"16.7","Single Cell Type RNA - Leydig cells [nTPM]":"6.2","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"5.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"58.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"22.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"5.6","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"81.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.3","Single Cell Type RNA - Spermatocytes [nTPM]":"2.7","Single Cell Type RNA - Spermatogonia [nTPM]":"3.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"0.7","Single Cell Type RNA - Theca cells [nTPM]":"7.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"SULT2B1","Gene synonym":["HSST2"],"Ensembl":"ENSG00000088002","Gene description":"Sulfotransferase family 2B member 1","Uniprot":["O00204"],"Chromosome":"19","Position":"48552172-48599425","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid metabolism","Steroid metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"286.0","skin 1":"186.5","vagina":"145.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Prostatic glandular cells":"62.3","Proximal enterocytes":"75.9","Squamous epithelial cells":"56.0","Suprabasal keratinocytes":"137.4","Urothelial cells":"114.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"CAPAN-2":"74.2","MCF7":"46.8","OE19":"122.9","T-47d":"36.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041724","HPA043539","HPA076510"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA041724":"AB_2677638","HPA043539":"AB_2678540","HPA076510":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"11.5","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"0.8","Tissue RNA - cervix [nTPM]":"74.4","Tissue RNA - choroid plexus [nTPM]":"0.4","Tissue RNA - colon [nTPM]":"0.8","Tissue RNA - duodenum [nTPM]":"9.3","Tissue RNA - endometrium 1 [nTPM]":"0.5","Tissue RNA - epididymis [nTPM]":"6.8","Tissue RNA - esophagus [nTPM]":"286.0","Tissue RNA - fallopian tube [nTPM]":"1.2","Tissue RNA - gallbladder [nTPM]":"2.7","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.5","Tissue RNA - kidney [nTPM]":"13.0","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"9.4","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.7","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.7","Tissue RNA - parathyroid gland [nTPM]":"7.9","Tissue RNA - pituitary gland [nTPM]":"0.4","Tissue RNA - placenta [nTPM]":"1.5","Tissue RNA - pons [nTPM]":"0.5","Tissue RNA - prostate [nTPM]":"22.6","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"53.6","Tissue RNA - seminal vesicle [nTPM]":"3.7","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"186.5","Tissue RNA - small intestine [nTPM]":"18.2","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.4","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"3.5","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"0.9","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"1.9","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"28.3","Tissue RNA - urinary bladder [nTPM]":"0.7","Tissue RNA - vagina [nTPM]":"145.9","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"12.6","Cell RNA - A549 [nTPM]":"15.8","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.9","Cell RNA - CAPAN-2 [nTPM]":"74.2","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.7","Cell RNA - HaCaT [nTPM]":"3.9","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.5","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"7.2","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"2.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.8","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"46.8","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"122.9","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"3.5","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"6.2","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"36.7","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"0.8","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.5","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.7","Brain RNA - pons [nTPM]":"0.5","Brain RNA - spinal cord [nTPM]":"0.4","Brain RNA - thalamus [nTPM]":"0.9","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"24.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"30.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"40.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"12.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.6","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"4.8","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.5","Single Cell Type RNA - Paneth cells [nTPM]":"7.9","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"62.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"75.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"11.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"56.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"137.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"2.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.2","Single Cell Type RNA - Urothelial cells [nTPM]":"114.6"},{"Gene":"SUMF1","Gene synonym":["FGE","UNQ3037"],"Ensembl":"ENSG00000144455","Gene description":"Sulfatase modifying factor 1","Uniprot":["Q8NBK3"],"Chromosome":"3","Position":"3700814-4467273","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Ichthyosis","Leukodystrophy","Metachromatic leukodystrophy","Mucopolysaccharidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"85.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"116.4","hTERT-RPE1":"117.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038025"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2800000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038025":"AB_10675624"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.79e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-2"},"Tissue RNA - adipose tissue [nTPM]":"20.7","Tissue RNA - adrenal gland [nTPM]":"19.5","Tissue RNA - amygdala [nTPM]":"10.4","Tissue RNA - appendix [nTPM]":"13.1","Tissue RNA - basal ganglia [nTPM]":"12.0","Tissue RNA - bone marrow [nTPM]":"10.2","Tissue RNA - breast [nTPM]":"29.2","Tissue RNA - cerebellum [nTPM]":"10.9","Tissue RNA - cerebral cortex [nTPM]":"12.2","Tissue RNA - cervix [nTPM]":"21.3","Tissue RNA - choroid plexus [nTPM]":"15.6","Tissue RNA - colon [nTPM]":"23.9","Tissue RNA - duodenum [nTPM]":"13.3","Tissue RNA - endometrium 1 [nTPM]":"15.8","Tissue RNA - epididymis [nTPM]":"26.8","Tissue RNA - esophagus [nTPM]":"28.7","Tissue RNA - fallopian tube [nTPM]":"25.6","Tissue RNA - gallbladder [nTPM]":"19.7","Tissue RNA - heart muscle [nTPM]":"12.5","Tissue RNA - hippocampal formation [nTPM]":"10.2","Tissue RNA - hypothalamus [nTPM]":"12.2","Tissue RNA - kidney [nTPM]":"39.3","Tissue RNA - liver [nTPM]":"27.4","Tissue RNA - lung [nTPM]":"23.0","Tissue RNA - lymph node [nTPM]":"12.6","Tissue RNA - medulla oblongata [nTPM]":"12.2","Tissue RNA - midbrain [nTPM]":"11.7","Tissue RNA - ovary [nTPM]":"17.4","Tissue RNA - pancreas [nTPM]":"18.9","Tissue RNA - parathyroid gland [nTPM]":"46.8","Tissue RNA - pituitary gland [nTPM]":"14.5","Tissue RNA - placenta [nTPM]":"18.8","Tissue RNA - pons [nTPM]":"11.4","Tissue RNA - prostate [nTPM]":"22.1","Tissue RNA - rectum [nTPM]":"29.6","Tissue RNA - retina [nTPM]":"3.4","Tissue RNA - salivary gland [nTPM]":"22.8","Tissue RNA - seminal vesicle [nTPM]":"17.7","Tissue RNA - skeletal muscle [nTPM]":"4.3","Tissue RNA - skin 1 [nTPM]":"20.3","Tissue RNA - small intestine [nTPM]":"14.1","Tissue RNA - smooth muscle [nTPM]":"20.5","Tissue RNA - spinal cord [nTPM]":"11.4","Tissue RNA - spleen [nTPM]":"16.8","Tissue RNA - stomach 1 [nTPM]":"23.8","Tissue RNA - testis [nTPM]":"5.1","Tissue RNA - thalamus [nTPM]":"13.1","Tissue RNA - thymus [nTPM]":"10.6","Tissue RNA - thyroid gland [nTPM]":"28.4","Tissue RNA - tongue [nTPM]":"7.6","Tissue RNA - tonsil [nTPM]":"13.4","Tissue RNA - urinary bladder [nTPM]":"20.0","Tissue RNA - vagina [nTPM]":"18.5","Tissue RNA - white matter [nTPM]":"13.1","Cell RNA - A-431 [nTPM]":"25.0","Cell RNA - A549 [nTPM]":"20.6","Cell RNA - AF22 [nTPM]":"11.4","Cell RNA - AN3-CA [nTPM]":"6.3","Cell RNA - ASC diff [nTPM]":"116.4","Cell RNA - ASC TERT1 [nTPM]":"61.3","Cell RNA - BEWO [nTPM]":"21.9","Cell RNA - BJ [nTPM]":"34.4","Cell RNA - BJ hTERT+ [nTPM]":"53.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"18.2","Cell RNA - CACO-2 [nTPM]":"9.6","Cell RNA - CAPAN-2 [nTPM]":"78.9","Cell RNA - Daudi [nTPM]":"3.7","Cell RNA - EFO-21 [nTPM]":"20.3","Cell RNA - fHDF\/TERT166 [nTPM]":"63.0","Cell RNA - GAMG [nTPM]":"24.3","Cell RNA - HaCaT [nTPM]":"13.3","Cell RNA - HAP1 [nTPM]":"5.0","Cell RNA - HBEC3-KT [nTPM]":"39.0","Cell RNA - HBF TERT88 [nTPM]":"25.2","Cell RNA - HDLM-2 [nTPM]":"12.0","Cell RNA - HEK 293 [nTPM]":"10.1","Cell RNA - HEL [nTPM]":"5.4","Cell RNA - HeLa [nTPM]":"18.9","Cell RNA - Hep G2 [nTPM]":"26.2","Cell RNA - HHSteC [nTPM]":"30.0","Cell RNA - HL-60 [nTPM]":"6.1","Cell RNA - HMC-1 [nTPM]":"14.4","Cell RNA - HSkMC [nTPM]":"56.6","Cell RNA - hTCEpi [nTPM]":"43.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.2","Cell RNA - hTERT-HME1 [nTPM]":"5.3","Cell RNA - hTERT-RPE1 [nTPM]":"117.9","Cell RNA - HUVEC TERT2 [nTPM]":"44.8","Cell RNA - JURKAT [nTPM]":"8.9","Cell RNA - K-562 [nTPM]":"9.1","Cell RNA - Karpas-707 [nTPM]":"8.4","Cell RNA - LHCN-M2 [nTPM]":"45.8","Cell RNA - MCF7 [nTPM]":"40.2","Cell RNA - MOLT-4 [nTPM]":"3.4","Cell RNA - NB-4 [nTPM]":"9.1","Cell RNA - NTERA-2 [nTPM]":"12.0","Cell RNA - OE19 [nTPM]":"22.8","Cell RNA - PC-3 [nTPM]":"23.4","Cell RNA - REH [nTPM]":"6.3","Cell RNA - RH-30 [nTPM]":"17.0","Cell RNA - RPMI-8226 [nTPM]":"16.0","Cell RNA - RPTEC TERT1 [nTPM]":"86.6","Cell RNA - RT4 [nTPM]":"28.0","Cell RNA - SCLC-21H [nTPM]":"2.2","Cell RNA - SH-SY5Y [nTPM]":"12.6","Cell RNA - SiHa [nTPM]":"24.6","Cell RNA - SK-BR-3 [nTPM]":"56.8","Cell RNA - SK-MEL-30 [nTPM]":"20.4","Cell RNA - SuSa [nTPM]":"19.5","Cell RNA - T-47d [nTPM]":"75.7","Cell RNA - THP-1 [nTPM]":"15.6","Cell RNA - TIME [nTPM]":"41.4","Cell RNA - U-138 MG [nTPM]":"32.5","Cell RNA - U-2 OS [nTPM]":"4.2","Cell RNA - U-2197 [nTPM]":"25.3","Cell RNA - U-251 MG [nTPM]":"21.0","Cell RNA - U-266\/70 [nTPM]":"10.4","Cell RNA - U-266\/84 [nTPM]":"22.8","Cell RNA - U-698 [nTPM]":"1.7","Cell RNA - U-87 MG [nTPM]":"63.2","Cell RNA - U-937 [nTPM]":"13.5","Cell RNA - WM-115 [nTPM]":"24.7","Blood RNA - basophil [nTPM]":"66.1","Blood RNA - classical monocyte [nTPM]":"100.5","Blood RNA - eosinophil [nTPM]":"35.6","Blood RNA - gdT-cell [nTPM]":"38.9","Blood RNA - intermediate monocyte [nTPM]":"81.8","Blood RNA - MAIT T-cell [nTPM]":"35.2","Blood RNA - memory B-cell [nTPM]":"26.6","Blood RNA - memory CD4 T-cell [nTPM]":"31.2","Blood RNA - memory CD8 T-cell [nTPM]":"32.9","Blood RNA - myeloid DC [nTPM]":"86.6","Blood RNA - naive B-cell [nTPM]":"30.7","Blood RNA - naive CD4 T-cell [nTPM]":"39.4","Blood RNA - naive CD8 T-cell [nTPM]":"32.0","Blood RNA - neutrophil [nTPM]":"36.2","Blood RNA - NK-cell [nTPM]":"42.0","Blood RNA - non-classical monocyte [nTPM]":"78.2","Blood RNA - plasmacytoid DC [nTPM]":"45.9","Blood RNA - T-reg [nTPM]":"16.9","Blood RNA - total PBMC [nTPM]":"90.2","Brain RNA - amygdala [nTPM]":"10.4","Brain RNA - basal ganglia [nTPM]":"12.0","Brain RNA - cerebellum [nTPM]":"10.9","Brain RNA - cerebral cortex [nTPM]":"12.2","Brain RNA - hippocampal formation [nTPM]":"10.2","Brain RNA - hypothalamus [nTPM]":"12.2","Brain RNA - medulla oblongata [nTPM]":"12.2","Brain RNA - midbrain [nTPM]":"11.7","Brain RNA - pons [nTPM]":"11.4","Brain RNA - spinal cord [nTPM]":"11.4","Brain RNA - thalamus [nTPM]":"13.1","Brain RNA - white matter [nTPM]":"13.1","Single Cell Type RNA - Adipocytes [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.1","Single Cell Type RNA - Astrocytes [nTPM]":"36.9","Single Cell Type RNA - B-cells [nTPM]":"13.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"32.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.1","Single Cell Type RNA - Bipolar cells [nTPM]":"5.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"16.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"29.8","Single Cell Type RNA - dendritic cells [nTPM]":"9.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"39.3","Single Cell Type RNA - Early spermatids [nTPM]":"26.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.1","Single Cell Type RNA - Endothelial cells [nTPM]":"13.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"11.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"53.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"23.3","Single Cell Type RNA - Fibroblasts [nTPM]":"25.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.9","Single Cell Type RNA - granulocytes [nTPM]":"17.1","Single Cell Type RNA - Granulosa cells [nTPM]":"10.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.5","Single Cell Type RNA - Hepatocytes [nTPM]":"18.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.2","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"57.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.7","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"37.1","Single Cell Type RNA - Langerhans cells [nTPM]":"12.0","Single Cell Type RNA - Late spermatids [nTPM]":"10.7","Single Cell Type RNA - Leydig cells [nTPM]":"16.4","Single Cell Type RNA - Macrophages [nTPM]":"24.3","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"62.8","Single Cell Type RNA - monocytes [nTPM]":"43.9","Single Cell Type RNA - Muller glia cells [nTPM]":"6.8","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"56.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"85.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.0","Single Cell Type RNA - Paneth cells [nTPM]":"16.4","Single Cell Type RNA - Peritubular cells [nTPM]":"17.3","Single Cell Type RNA - Plasma cells [nTPM]":"11.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.5","Single Cell Type RNA - Spermatocytes [nTPM]":"4.8","Single Cell Type RNA - Spermatogonia [nTPM]":"5.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"24.4","Single Cell Type RNA - T-cells [nTPM]":"11.6","Single Cell Type RNA - Theca cells [nTPM]":"11.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"25.6","Single Cell Type RNA - Urothelial cells [nTPM]":"18.3"},{"Gene":"SUOX","Gene synonym":[],"Ensembl":"ENSG00000139531","Gene description":"Sulfite oxidase","Uniprot":["P51687"],"Chromosome":"12","Position":"55997180-56006641","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"49.6","Proximal tubular cells":"35.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"T-47d":"72.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038208","HPA038209"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"44000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038208":"AB_2675892","HPA038209":"AB_10672738"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.72e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.28e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.77e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.32e-5"},"Tissue RNA - adipose tissue [nTPM]":"19.2","Tissue RNA - adrenal gland [nTPM]":"35.2","Tissue RNA - amygdala [nTPM]":"19.3","Tissue RNA - appendix [nTPM]":"9.5","Tissue RNA - basal ganglia [nTPM]":"20.2","Tissue RNA - bone marrow [nTPM]":"12.8","Tissue RNA - breast [nTPM]":"18.2","Tissue RNA - cerebellum [nTPM]":"21.0","Tissue RNA - cerebral cortex [nTPM]":"22.6","Tissue RNA - cervix [nTPM]":"16.7","Tissue RNA - choroid plexus [nTPM]":"22.2","Tissue RNA - colon [nTPM]":"20.6","Tissue RNA - duodenum [nTPM]":"19.3","Tissue RNA - endometrium 1 [nTPM]":"17.6","Tissue RNA - epididymis [nTPM]":"33.0","Tissue RNA - esophagus [nTPM]":"21.5","Tissue RNA - fallopian tube [nTPM]":"22.9","Tissue RNA - gallbladder [nTPM]":"16.7","Tissue RNA - heart muscle [nTPM]":"29.4","Tissue RNA - hippocampal formation [nTPM]":"19.6","Tissue RNA - hypothalamus [nTPM]":"19.9","Tissue RNA - kidney [nTPM]":"40.8","Tissue RNA - liver [nTPM]":"72.3","Tissue RNA - lung [nTPM]":"15.6","Tissue RNA - lymph node [nTPM]":"8.3","Tissue RNA - medulla oblongata [nTPM]":"20.7","Tissue RNA - midbrain [nTPM]":"20.0","Tissue RNA - ovary [nTPM]":"22.1","Tissue RNA - pancreas [nTPM]":"17.4","Tissue RNA - parathyroid gland [nTPM]":"48.6","Tissue RNA - pituitary gland [nTPM]":"16.6","Tissue RNA - placenta [nTPM]":"11.5","Tissue RNA - pons [nTPM]":"20.6","Tissue RNA - prostate [nTPM]":"25.2","Tissue RNA - rectum [nTPM]":"17.1","Tissue RNA - retina [nTPM]":"13.8","Tissue RNA - salivary gland [nTPM]":"20.2","Tissue RNA - seminal vesicle [nTPM]":"24.5","Tissue RNA - skeletal muscle [nTPM]":"45.6","Tissue RNA - skin 1 [nTPM]":"10.4","Tissue RNA - small intestine [nTPM]":"15.6","Tissue RNA - smooth muscle [nTPM]":"17.4","Tissue RNA - spinal cord [nTPM]":"20.1","Tissue RNA - spleen [nTPM]":"13.6","Tissue RNA - stomach 1 [nTPM]":"21.3","Tissue RNA - testis [nTPM]":"8.3","Tissue RNA - thalamus [nTPM]":"21.7","Tissue RNA - thymus [nTPM]":"6.7","Tissue RNA - thyroid gland [nTPM]":"18.2","Tissue RNA - tongue [nTPM]":"28.8","Tissue RNA - tonsil [nTPM]":"12.0","Tissue RNA - urinary bladder [nTPM]":"21.2","Tissue RNA - vagina [nTPM]":"14.3","Tissue RNA - white matter [nTPM]":"24.0","Cell RNA - A-431 [nTPM]":"10.2","Cell RNA - A549 [nTPM]":"29.8","Cell RNA - AF22 [nTPM]":"18.5","Cell RNA - AN3-CA [nTPM]":"30.2","Cell RNA - ASC diff [nTPM]":"29.6","Cell RNA - ASC TERT1 [nTPM]":"12.2","Cell RNA - BEWO [nTPM]":"40.1","Cell RNA - BJ [nTPM]":"11.5","Cell RNA - BJ hTERT+ [nTPM]":"12.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.1","Cell RNA - CACO-2 [nTPM]":"28.8","Cell RNA - CAPAN-2 [nTPM]":"22.1","Cell RNA - Daudi [nTPM]":"1.2","Cell RNA - EFO-21 [nTPM]":"19.8","Cell RNA - fHDF\/TERT166 [nTPM]":"14.0","Cell RNA - GAMG [nTPM]":"10.6","Cell RNA - HaCaT [nTPM]":"13.2","Cell RNA - HAP1 [nTPM]":"13.7","Cell RNA - HBEC3-KT [nTPM]":"14.5","Cell RNA - HBF TERT88 [nTPM]":"8.2","Cell RNA - HDLM-2 [nTPM]":"45.8","Cell RNA - HEK 293 [nTPM]":"9.0","Cell RNA - HEL [nTPM]":"15.7","Cell RNA - HeLa [nTPM]":"19.4","Cell RNA - Hep G2 [nTPM]":"34.9","Cell RNA - HHSteC [nTPM]":"10.9","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"25.9","Cell RNA - HSkMC [nTPM]":"19.0","Cell RNA - hTCEpi [nTPM]":"5.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.1","Cell RNA - hTERT-HME1 [nTPM]":"6.8","Cell RNA - hTERT-RPE1 [nTPM]":"23.0","Cell RNA - HUVEC TERT2 [nTPM]":"38.9","Cell RNA - JURKAT [nTPM]":"1.6","Cell RNA - K-562 [nTPM]":"28.2","Cell RNA - Karpas-707 [nTPM]":"19.0","Cell RNA - LHCN-M2 [nTPM]":"16.2","Cell RNA - MCF7 [nTPM]":"25.1","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"10.0","Cell RNA - NTERA-2 [nTPM]":"9.9","Cell RNA - OE19 [nTPM]":"15.6","Cell RNA - PC-3 [nTPM]":"21.4","Cell RNA - REH [nTPM]":"13.6","Cell RNA - RH-30 [nTPM]":"7.7","Cell RNA - RPMI-8226 [nTPM]":"22.4","Cell RNA - RPTEC TERT1 [nTPM]":"17.8","Cell RNA - RT4 [nTPM]":"20.4","Cell RNA - SCLC-21H [nTPM]":"9.2","Cell RNA - SH-SY5Y [nTPM]":"12.3","Cell RNA - SiHa [nTPM]":"21.1","Cell RNA - SK-BR-3 [nTPM]":"42.6","Cell RNA - SK-MEL-30 [nTPM]":"17.4","Cell RNA - SuSa [nTPM]":"17.2","Cell RNA - T-47d [nTPM]":"72.2","Cell RNA - THP-1 [nTPM]":"14.9","Cell RNA - TIME [nTPM]":"20.6","Cell RNA - U-138 MG [nTPM]":"8.5","Cell RNA - U-2 OS [nTPM]":"10.4","Cell RNA - U-2197 [nTPM]":"10.8","Cell RNA - U-251 MG [nTPM]":"8.2","Cell RNA - U-266\/70 [nTPM]":"22.0","Cell RNA - U-266\/84 [nTPM]":"21.3","Cell RNA - U-698 [nTPM]":"1.6","Cell RNA - U-87 MG [nTPM]":"13.7","Cell RNA - U-937 [nTPM]":"10.2","Cell RNA - WM-115 [nTPM]":"12.7","Blood RNA - basophil [nTPM]":"11.1","Blood RNA - classical monocyte [nTPM]":"12.6","Blood RNA - eosinophil [nTPM]":"29.6","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"18.7","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"16.1","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.9","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"5.1","Blood RNA - NK-cell [nTPM]":"16.5","Blood RNA - non-classical monocyte [nTPM]":"16.2","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"7.9","Blood RNA - total PBMC [nTPM]":"11.8","Brain RNA - amygdala [nTPM]":"19.3","Brain RNA - basal ganglia [nTPM]":"20.2","Brain RNA - cerebellum [nTPM]":"21.0","Brain RNA - cerebral cortex [nTPM]":"22.6","Brain RNA - hippocampal formation [nTPM]":"19.6","Brain RNA - hypothalamus [nTPM]":"19.9","Brain RNA - medulla oblongata [nTPM]":"20.7","Brain RNA - midbrain [nTPM]":"20.0","Brain RNA - pons [nTPM]":"20.6","Brain RNA - spinal cord [nTPM]":"20.1","Brain RNA - thalamus [nTPM]":"21.7","Brain RNA - white matter [nTPM]":"24.0","Single Cell Type RNA - Adipocytes [nTPM]":"4.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.9","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"5.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"21.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"12.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"29.7","Single Cell Type RNA - dendritic cells [nTPM]":"0.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"5.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.7","Single Cell Type RNA - Endothelial cells [nTPM]":"7.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"6.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.1","Single Cell Type RNA - Fibroblasts [nTPM]":"6.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.4","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"6.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.9","Single Cell Type RNA - Hepatocytes [nTPM]":"49.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.5","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"8.9","Single Cell Type RNA - Langerhans cells [nTPM]":"4.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"4.4","Single Cell Type RNA - Macrophages [nTPM]":"4.3","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"10.0","Single Cell Type RNA - Muller glia cells [nTPM]":"8.5","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.3","Single Cell Type RNA - Paneth cells [nTPM]":"7.4","Single Cell Type RNA - Peritubular cells [nTPM]":"9.1","Single Cell Type RNA - Plasma cells [nTPM]":"3.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"35.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.4","Single Cell Type RNA - Spermatocytes [nTPM]":"2.4","Single Cell Type RNA - Spermatogonia [nTPM]":"1.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"30.8","Single Cell Type RNA - T-cells [nTPM]":"1.6","Single Cell Type RNA - Theca cells [nTPM]":"6.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.7","Single Cell Type RNA - Urothelial cells [nTPM]":"3.0"},{"Gene":"SYNJ1","Gene synonym":["INPP5G","PARK20"],"Ensembl":"ENSG00000159082","Gene description":"Synaptojanin 1","Uniprot":["O43426"],"Chromosome":"21","Position":"32628759-32728040","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Endocytosis"],"Molecular function":["Hydrolase","RNA-binding"],"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"45.9","retina":"48.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"110.9","Inhibitory neurons":"91.5","Oligodendrocytes":"61.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011916"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"HPA011916":"AB_1857692"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.43e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.58e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.6","Tissue RNA - adrenal gland [nTPM]":"6.9","Tissue RNA - amygdala [nTPM]":"15.0","Tissue RNA - appendix [nTPM]":"5.3","Tissue RNA - basal ganglia [nTPM]":"22.8","Tissue RNA - bone marrow [nTPM]":"23.8","Tissue RNA - breast [nTPM]":"6.5","Tissue RNA - cerebellum [nTPM]":"1.1","Tissue RNA - cerebral cortex [nTPM]":"45.9","Tissue RNA - cervix [nTPM]":"6.2","Tissue RNA - choroid plexus [nTPM]":"3.5","Tissue RNA - colon [nTPM]":"5.6","Tissue RNA - duodenum [nTPM]":"4.0","Tissue RNA - endometrium 1 [nTPM]":"5.1","Tissue RNA - epididymis [nTPM]":"5.1","Tissue RNA - esophagus [nTPM]":"4.6","Tissue RNA - fallopian tube [nTPM]":"5.0","Tissue RNA - gallbladder [nTPM]":"5.2","Tissue RNA - heart muscle [nTPM]":"6.4","Tissue RNA - hippocampal formation [nTPM]":"22.1","Tissue RNA - hypothalamus [nTPM]":"9.8","Tissue RNA - kidney [nTPM]":"7.4","Tissue RNA - liver [nTPM]":"5.7","Tissue RNA - lung [nTPM]":"8.0","Tissue RNA - lymph node [nTPM]":"6.3","Tissue RNA - medulla oblongata [nTPM]":"19.5","Tissue RNA - midbrain [nTPM]":"5.6","Tissue RNA - ovary [nTPM]":"4.8","Tissue RNA - pancreas [nTPM]":"4.8","Tissue RNA - parathyroid gland [nTPM]":"8.4","Tissue RNA - pituitary gland [nTPM]":"13.8","Tissue RNA - placenta [nTPM]":"9.8","Tissue RNA - pons [nTPM]":"14.8","Tissue RNA - prostate [nTPM]":"4.5","Tissue RNA - rectum [nTPM]":"5.4","Tissue RNA - retina [nTPM]":"48.4","Tissue RNA - salivary gland [nTPM]":"4.7","Tissue RNA - seminal vesicle [nTPM]":"3.7","Tissue RNA - skeletal muscle [nTPM]":"7.7","Tissue RNA - skin 1 [nTPM]":"5.1","Tissue RNA - small intestine [nTPM]":"6.3","Tissue RNA - smooth muscle [nTPM]":"4.9","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"7.9","Tissue RNA - stomach 1 [nTPM]":"5.0","Tissue RNA - testis [nTPM]":"10.2","Tissue RNA - thalamus [nTPM]":"8.7","Tissue RNA - thymus [nTPM]":"7.1","Tissue RNA - thyroid gland [nTPM]":"7.3","Tissue RNA - tongue [nTPM]":"6.4","Tissue RNA - tonsil [nTPM]":"4.8","Tissue RNA - urinary bladder [nTPM]":"5.5","Tissue RNA - vagina [nTPM]":"5.4","Tissue RNA - white matter [nTPM]":"25.9","Cell RNA - A-431 [nTPM]":"5.5","Cell RNA - A549 [nTPM]":"2.9","Cell RNA - AF22 [nTPM]":"5.0","Cell RNA - AN3-CA [nTPM]":"5.7","Cell RNA - ASC diff [nTPM]":"8.9","Cell RNA - ASC TERT1 [nTPM]":"7.1","Cell RNA - BEWO [nTPM]":"10.3","Cell RNA - BJ [nTPM]":"11.3","Cell RNA - BJ hTERT+ [nTPM]":"6.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.7","Cell RNA - CACO-2 [nTPM]":"6.1","Cell RNA - CAPAN-2 [nTPM]":"2.6","Cell RNA - Daudi [nTPM]":"2.0","Cell RNA - EFO-21 [nTPM]":"3.8","Cell RNA - fHDF\/TERT166 [nTPM]":"6.9","Cell RNA - GAMG [nTPM]":"8.9","Cell RNA - HaCaT [nTPM]":"5.0","Cell RNA - HAP1 [nTPM]":"8.9","Cell RNA - HBEC3-KT [nTPM]":"6.8","Cell RNA - HBF TERT88 [nTPM]":"8.4","Cell RNA - HDLM-2 [nTPM]":"6.8","Cell RNA - HEK 293 [nTPM]":"8.1","Cell RNA - HEL [nTPM]":"13.8","Cell RNA - HeLa [nTPM]":"8.7","Cell RNA - Hep G2 [nTPM]":"3.5","Cell RNA - HHSteC [nTPM]":"4.8","Cell RNA - HL-60 [nTPM]":"5.6","Cell RNA - HMC-1 [nTPM]":"11.7","Cell RNA - HSkMC [nTPM]":"4.1","Cell RNA - hTCEpi [nTPM]":"4.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.0","Cell RNA - hTERT-HME1 [nTPM]":"6.1","Cell RNA - hTERT-RPE1 [nTPM]":"5.8","Cell RNA - HUVEC TERT2 [nTPM]":"10.8","Cell RNA - JURKAT [nTPM]":"7.3","Cell RNA - K-562 [nTPM]":"10.6","Cell RNA - Karpas-707 [nTPM]":"11.6","Cell RNA - LHCN-M2 [nTPM]":"9.0","Cell RNA - MCF7 [nTPM]":"5.5","Cell RNA - MOLT-4 [nTPM]":"5.5","Cell RNA - NB-4 [nTPM]":"5.1","Cell RNA - NTERA-2 [nTPM]":"3.4","Cell RNA - OE19 [nTPM]":"6.4","Cell RNA - PC-3 [nTPM]":"6.0","Cell RNA - REH [nTPM]":"6.1","Cell RNA - RH-30 [nTPM]":"11.1","Cell RNA - RPMI-8226 [nTPM]":"7.4","Cell RNA - RPTEC TERT1 [nTPM]":"7.5","Cell RNA - RT4 [nTPM]":"4.3","Cell RNA - SCLC-21H [nTPM]":"5.6","Cell RNA - SH-SY5Y [nTPM]":"4.5","Cell RNA - SiHa [nTPM]":"14.0","Cell RNA - SK-BR-3 [nTPM]":"8.4","Cell RNA - SK-MEL-30 [nTPM]":"5.6","Cell RNA - SuSa [nTPM]":"6.9","Cell RNA - T-47d [nTPM]":"7.8","Cell RNA - THP-1 [nTPM]":"7.2","Cell RNA - TIME [nTPM]":"11.2","Cell RNA - U-138 MG [nTPM]":"10.0","Cell RNA - U-2 OS [nTPM]":"5.3","Cell RNA - U-2197 [nTPM]":"8.2","Cell RNA - U-251 MG [nTPM]":"6.4","Cell RNA - U-266\/70 [nTPM]":"6.0","Cell RNA - U-266\/84 [nTPM]":"7.8","Cell RNA - U-698 [nTPM]":"4.4","Cell RNA - U-87 MG [nTPM]":"8.0","Cell RNA - U-937 [nTPM]":"10.7","Cell RNA - WM-115 [nTPM]":"8.7","Blood RNA - basophil [nTPM]":"3.4","Blood RNA - classical monocyte [nTPM]":"2.9","Blood RNA - eosinophil [nTPM]":"6.9","Blood RNA - gdT-cell [nTPM]":"1.2","Blood RNA - intermediate monocyte [nTPM]":"5.2","Blood RNA - MAIT T-cell [nTPM]":"2.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"1.9","Blood RNA - memory CD8 T-cell [nTPM]":"2.0","Blood RNA - myeloid DC [nTPM]":"2.5","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"2.2","Blood RNA - naive CD8 T-cell [nTPM]":"2.2","Blood RNA - neutrophil [nTPM]":"9.1","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"4.7","Blood RNA - plasmacytoid DC [nTPM]":"1.4","Blood RNA - T-reg [nTPM]":"2.6","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"15.0","Brain RNA - basal ganglia [nTPM]":"22.8","Brain RNA - cerebellum [nTPM]":"1.1","Brain RNA - cerebral cortex [nTPM]":"45.9","Brain RNA - hippocampal formation [nTPM]":"22.1","Brain RNA - hypothalamus [nTPM]":"9.8","Brain RNA - medulla oblongata [nTPM]":"19.5","Brain RNA - midbrain [nTPM]":"5.6","Brain RNA - pons [nTPM]":"14.8","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"8.7","Brain RNA - white matter [nTPM]":"25.9","Single Cell Type RNA - Adipocytes [nTPM]":"10.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.4","Single Cell Type RNA - Astrocytes [nTPM]":"22.9","Single Cell Type RNA - B-cells [nTPM]":"3.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"24.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"4.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"17.7","Single Cell Type RNA - dendritic cells [nTPM]":"7.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.0","Single Cell Type RNA - Early spermatids [nTPM]":"19.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.7","Single Cell Type RNA - Endothelial cells [nTPM]":"11.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"110.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.8","Single Cell Type RNA - Fibroblasts [nTPM]":"5.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.6","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"2.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"4.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.1","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"91.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"18.6","Single Cell Type RNA - Langerhans cells [nTPM]":"5.7","Single Cell Type RNA - Late spermatids [nTPM]":"11.3","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"15.7","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"31.9","Single Cell Type RNA - monocytes [nTPM]":"6.5","Single Cell Type RNA - Muller glia cells [nTPM]":"21.8","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"49.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"61.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.8","Single Cell Type RNA - Paneth cells [nTPM]":"5.3","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"8.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"45.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.8","Single Cell Type RNA - Spermatocytes [nTPM]":"22.1","Single Cell Type RNA - Spermatogonia [nTPM]":"13.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"38.0","Single Cell Type RNA - T-cells [nTPM]":"9.9","Single Cell Type RNA - Theca cells [nTPM]":"2.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.4","Single Cell Type RNA - Urothelial cells [nTPM]":"4.3"},{"Gene":"SYP","Gene synonym":["MRX96"],"Ensembl":"ENSG00000102003","Gene description":"Synaptophysin","Uniprot":["P08247"],"Chromosome":"X","Position":"49187815-49200199","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"259.4","pituitary gland":"106.8","retina":"316.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Bipolar cells":"529.2","Cone photoreceptor cells":"546.3","Rod photoreceptor cells":"594.4"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"12.8","pancreatic cancer":"5.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"K-562":"20.3","SCLC-21H":"102.6","SH-SY5Y":"36.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000076","HPA002858","CAB055505","CAB078999","HPA079659"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB000076":"AB_2315411","CAB055505":"AB_564017","CAB078999":null,"HPA002858":"AB_1080153","HPA079659":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.52e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Tissue RNA - adipose tissue [nTPM]":"2.6","Tissue RNA - adrenal gland [nTPM]":"40.1","Tissue RNA - amygdala [nTPM]":"115.7","Tissue RNA - appendix [nTPM]":"3.6","Tissue RNA - basal ganglia [nTPM]":"132.0","Tissue RNA - bone marrow [nTPM]":"0.8","Tissue RNA - breast [nTPM]":"1.9","Tissue RNA - cerebellum [nTPM]":"26.0","Tissue RNA - cerebral cortex [nTPM]":"259.4","Tissue RNA - cervix [nTPM]":"1.8","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"7.4","Tissue RNA - duodenum [nTPM]":"12.4","Tissue RNA - endometrium 1 [nTPM]":"1.5","Tissue RNA - epididymis [nTPM]":"2.0","Tissue RNA - esophagus [nTPM]":"1.2","Tissue RNA - fallopian tube [nTPM]":"1.7","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"3.1","Tissue RNA - hippocampal formation [nTPM]":"144.0","Tissue RNA - hypothalamus [nTPM]":"137.9","Tissue RNA - kidney [nTPM]":"5.0","Tissue RNA - liver [nTPM]":"0.8","Tissue RNA - lung [nTPM]":"3.0","Tissue RNA - lymph node [nTPM]":"0.9","Tissue RNA - medulla oblongata [nTPM]":"89.5","Tissue RNA - midbrain [nTPM]":"25.8","Tissue RNA - ovary [nTPM]":"1.7","Tissue RNA - pancreas [nTPM]":"7.6","Tissue RNA - parathyroid gland [nTPM]":"3.3","Tissue RNA - pituitary gland [nTPM]":"106.8","Tissue RNA - placenta [nTPM]":"0.8","Tissue RNA - pons [nTPM]":"76.2","Tissue RNA - prostate [nTPM]":"1.6","Tissue RNA - rectum [nTPM]":"3.9","Tissue RNA - retina [nTPM]":"316.3","Tissue RNA - salivary gland [nTPM]":"1.3","Tissue RNA - seminal vesicle [nTPM]":"1.1","Tissue RNA - skeletal muscle [nTPM]":"1.9","Tissue RNA - skin 1 [nTPM]":"1.8","Tissue RNA - small intestine [nTPM]":"13.9","Tissue RNA - smooth muscle [nTPM]":"1.9","Tissue RNA - spinal cord [nTPM]":"4.7","Tissue RNA - spleen [nTPM]":"2.0","Tissue RNA - stomach 1 [nTPM]":"5.3","Tissue RNA - testis [nTPM]":"1.7","Tissue RNA - thalamus [nTPM]":"86.0","Tissue RNA - thymus [nTPM]":"4.2","Tissue RNA - thyroid gland [nTPM]":"2.3","Tissue RNA - tongue [nTPM]":"1.4","Tissue RNA - tonsil [nTPM]":"0.7","Tissue RNA - urinary bladder [nTPM]":"1.5","Tissue RNA - vagina [nTPM]":"2.2","Tissue RNA - white matter [nTPM]":"116.9","Cell RNA - A-431 [nTPM]":"0.9","Cell RNA - A549 [nTPM]":"3.9","Cell RNA - AF22 [nTPM]":"2.9","Cell RNA - AN3-CA [nTPM]":"5.8","Cell RNA - ASC diff [nTPM]":"3.2","Cell RNA - ASC TERT1 [nTPM]":"0.5","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.8","Cell RNA - CACO-2 [nTPM]":"3.6","Cell RNA - CAPAN-2 [nTPM]":"2.1","Cell RNA - Daudi [nTPM]":"3.2","Cell RNA - EFO-21 [nTPM]":"0.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"4.4","Cell RNA - HaCaT [nTPM]":"2.9","Cell RNA - HAP1 [nTPM]":"3.1","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"0.7","Cell RNA - HDLM-2 [nTPM]":"6.5","Cell RNA - HEK 293 [nTPM]":"3.5","Cell RNA - HEL [nTPM]":"4.9","Cell RNA - HeLa [nTPM]":"1.4","Cell RNA - Hep G2 [nTPM]":"1.1","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.6","Cell RNA - HMC-1 [nTPM]":"10.5","Cell RNA - HSkMC [nTPM]":"0.4","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.5","Cell RNA - hTERT-HME1 [nTPM]":"0.7","Cell RNA - hTERT-RPE1 [nTPM]":"0.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"2.7","Cell RNA - K-562 [nTPM]":"20.3","Cell RNA - Karpas-707 [nTPM]":"7.6","Cell RNA - LHCN-M2 [nTPM]":"0.6","Cell RNA - MCF7 [nTPM]":"1.1","Cell RNA - MOLT-4 [nTPM]":"1.7","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"9.6","Cell RNA - OE19 [nTPM]":"2.5","Cell RNA - PC-3 [nTPM]":"0.8","Cell RNA - REH [nTPM]":"0.6","Cell RNA - RH-30 [nTPM]":"0.6","Cell RNA - RPMI-8226 [nTPM]":"1.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"102.6","Cell RNA - SH-SY5Y [nTPM]":"36.8","Cell RNA - SiHa [nTPM]":"1.1","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"1.5","Cell RNA - SuSa [nTPM]":"0.9","Cell RNA - T-47d [nTPM]":"1.9","Cell RNA - THP-1 [nTPM]":"1.8","Cell RNA - TIME [nTPM]":"0.6","Cell RNA - U-138 MG [nTPM]":"0.6","Cell RNA - U-2 OS [nTPM]":"3.2","Cell RNA - U-2197 [nTPM]":"1.0","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"6.7","Cell RNA - U-698 [nTPM]":"0.8","Cell RNA - U-87 MG [nTPM]":"1.7","Cell RNA - U-937 [nTPM]":"1.3","Cell RNA - WM-115 [nTPM]":"3.2","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"1.9","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"115.7","Brain RNA - basal ganglia [nTPM]":"132.0","Brain RNA - cerebellum [nTPM]":"26.0","Brain RNA - cerebral cortex [nTPM]":"259.4","Brain RNA - hippocampal formation [nTPM]":"144.0","Brain RNA - hypothalamus [nTPM]":"137.9","Brain RNA - medulla oblongata [nTPM]":"89.5","Brain RNA - midbrain [nTPM]":"25.8","Brain RNA - pons [nTPM]":"76.2","Brain RNA - spinal cord [nTPM]":"4.7","Brain RNA - thalamus [nTPM]":"86.0","Brain RNA - white matter [nTPM]":"116.9","Single Cell Type RNA - Adipocytes [nTPM]":"7.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.9","Single Cell Type RNA - Astrocytes [nTPM]":"24.2","Single Cell Type RNA - B-cells [nTPM]":"6.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"529.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"2.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"546.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - dendritic cells [nTPM]":"1.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.9","Single Cell Type RNA - Early spermatids [nTPM]":"10.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.1","Single Cell Type RNA - Endothelial cells [nTPM]":"6.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"116.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"115.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.6","Single Cell Type RNA - Fibroblasts [nTPM]":"3.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.1","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"3.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"1.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.2","Single Cell Type RNA - Horizontal cells [nTPM]":"122.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"118.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"37.7","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"4.9","Single Cell Type RNA - Late spermatids [nTPM]":"12.6","Single Cell Type RNA - Leydig cells [nTPM]":"4.1","Single Cell Type RNA - Macrophages [nTPM]":"3.6","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"2.7","Single Cell Type RNA - Muller glia cells [nTPM]":"54.4","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"28.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"33.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.2","Single Cell Type RNA - Paneth cells [nTPM]":"2.1","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"1.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"16.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"594.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.8","Single Cell Type RNA - Spermatocytes [nTPM]":"2.4","Single Cell Type RNA - Spermatogonia [nTPM]":"2.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - T-cells [nTPM]":"3.5","Single Cell Type RNA - Theca cells [nTPM]":"41.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.8","Single Cell Type RNA - Urothelial cells [nTPM]":"1.0"},{"Gene":"SYT1","Gene synonym":["P65","SVP65","SYT"],"Ensembl":"ENSG00000067715","Gene description":"Synaptotagmin 1","Uniprot":["P21579"],"Chromosome":"12","Position":"78863993-79452008","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Differentiation"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"brain":"403.3","retina":"197.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"1287.6","Cone photoreceptor cells":"894.5","Excitatory neurons":"3753.2","Inhibitory neurons":"2910.4","Rod photoreceptor cells":"905.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"10","RNA brain regional specific nTPM":{"amygdala":"113.1","basal ganglia":"153.7","cerebral cortex":"403.3","hippocampal formation":"134.2","white matter":"146.0"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"1.0","naive B-cell":"1.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTERT-HME1":"39.4","hTERT-RPE1":"37.1","LHCN-M2":"31.9","SH-SY5Y":"30.9","WM-115":"29.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008394","HPA064788"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA008394":"AB_1857696","HPA064788":"AB_2685351"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"21.7","Tissue RNA - amygdala [nTPM]":"113.1","Tissue RNA - appendix [nTPM]":"2.2","Tissue RNA - basal ganglia [nTPM]":"153.7","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"0.7","Tissue RNA - cerebellum [nTPM]":"19.7","Tissue RNA - cerebral cortex [nTPM]":"403.3","Tissue RNA - cervix [nTPM]":"1.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"4.4","Tissue RNA - duodenum [nTPM]":"1.5","Tissue RNA - endometrium 1 [nTPM]":"9.9","Tissue RNA - epididymis [nTPM]":"0.7","Tissue RNA - esophagus [nTPM]":"0.7","Tissue RNA - fallopian tube [nTPM]":"0.8","Tissue RNA - gallbladder [nTPM]":"1.3","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"134.2","Tissue RNA - hypothalamus [nTPM]":"2.0","Tissue RNA - kidney [nTPM]":"1.9","Tissue RNA - liver [nTPM]":"1.9","Tissue RNA - lung [nTPM]":"0.9","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"5.2","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"6.4","Tissue RNA - placenta [nTPM]":"2.6","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"6.6","Tissue RNA - rectum [nTPM]":"2.8","Tissue RNA - retina [nTPM]":"197.7","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"5.5","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"3.4","Tissue RNA - smooth muscle [nTPM]":"25.2","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"2.6","Tissue RNA - stomach 1 [nTPM]":"1.3","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"12.5","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.5","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"1.6","Tissue RNA - vagina [nTPM]":"2.5","Tissue RNA - white matter [nTPM]":"146.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"19.2","Cell RNA - AF22 [nTPM]":"14.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"1.4","Cell RNA - ASC TERT1 [nTPM]":"4.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"1.4","Cell RNA - BJ hTERT+ [nTPM]":"1.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.1","Cell RNA - CACO-2 [nTPM]":"1.0","Cell RNA - CAPAN-2 [nTPM]":"0.5","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"2.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"5.0","Cell RNA - HaCaT [nTPM]":"0.6","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"2.2","Cell RNA - HBF TERT88 [nTPM]":"1.6","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"0.7","Cell RNA - HEL [nTPM]":"1.0","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"3.6","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"1.1","Cell RNA - hTCEpi [nTPM]":"1.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.2","Cell RNA - hTERT-HME1 [nTPM]":"39.4","Cell RNA - hTERT-RPE1 [nTPM]":"37.1","Cell RNA - HUVEC TERT2 [nTPM]":"13.6","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"2.2","Cell RNA - LHCN-M2 [nTPM]":"31.9","Cell RNA - MCF7 [nTPM]":"3.1","Cell RNA - MOLT-4 [nTPM]":"1.8","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"10.3","Cell RNA - OE19 [nTPM]":"2.1","Cell RNA - PC-3 [nTPM]":"5.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"14.3","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"5.5","Cell RNA - SCLC-21H [nTPM]":"18.8","Cell RNA - SH-SY5Y [nTPM]":"30.9","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"2.4","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"9.5","Cell RNA - T-47d [nTPM]":"6.8","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"5.4","Cell RNA - U-138 MG [nTPM]":"2.0","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"6.2","Cell RNA - U-266\/70 [nTPM]":"3.4","Cell RNA - U-266\/84 [nTPM]":"8.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"4.5","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"29.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.7","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"1.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"1.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"113.1","Brain RNA - basal ganglia [nTPM]":"153.7","Brain RNA - cerebellum [nTPM]":"19.7","Brain RNA - cerebral cortex [nTPM]":"403.3","Brain RNA - hippocampal formation [nTPM]":"134.2","Brain RNA - hypothalamus [nTPM]":"2.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"12.5","Brain RNA - white matter [nTPM]":"146.0","Single Cell Type RNA - Adipocytes [nTPM]":"2.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"124.7","Single Cell Type RNA - B-cells [nTPM]":"9.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1287.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"894.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.2","Single Cell Type RNA - Endothelial cells [nTPM]":"10.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"96.9","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"3753.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.2","Single Cell Type RNA - Fibroblasts [nTPM]":"5.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.9","Single Cell Type RNA - Horizontal cells [nTPM]":"62.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2910.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.7","Single Cell Type RNA - Langerhans cells [nTPM]":"7.2","Single Cell Type RNA - Late spermatids [nTPM]":"2.9","Single Cell Type RNA - Leydig cells [nTPM]":"69.3","Single Cell Type RNA - Macrophages [nTPM]":"1.6","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"137.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"337.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"126.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"105.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"7.6","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"8.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"905.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.7","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"5.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.9","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"1.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"SYVN1","Gene synonym":["DER3","HRD1"],"Ensembl":"ENSG00000162298","Gene description":"Synoviolin 1","Uniprot":["Q86TM6"],"Chromosome":"11","Position":"65121780-65134532","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Stress response","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"72.9","Plasma cells":"90.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-698":"205.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005480","HPA024300","CAB037030"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Endoplasmic reticulum","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Endoplasmic reticulum","Plasma membrane"],"Antibody RRID":{"CAB037030":"AB_1840939","HPA005480":"AB_1079084","HPA024300":"AB_1851073"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.88e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Tissue RNA - adipose tissue [nTPM]":"29.2","Tissue RNA - adrenal gland [nTPM]":"40.3","Tissue RNA - amygdala [nTPM]":"19.3","Tissue RNA - appendix [nTPM]":"37.1","Tissue RNA - basal ganglia [nTPM]":"25.6","Tissue RNA - bone marrow [nTPM]":"31.0","Tissue RNA - breast [nTPM]":"27.6","Tissue RNA - cerebellum [nTPM]":"23.2","Tissue RNA - cerebral cortex [nTPM]":"21.4","Tissue RNA - cervix [nTPM]":"30.7","Tissue RNA - choroid plexus [nTPM]":"26.7","Tissue RNA - colon [nTPM]":"29.2","Tissue RNA - duodenum [nTPM]":"26.1","Tissue RNA - endometrium 1 [nTPM]":"29.1","Tissue RNA - epididymis [nTPM]":"38.8","Tissue RNA - esophagus [nTPM]":"28.4","Tissue RNA - fallopian tube [nTPM]":"30.6","Tissue RNA - gallbladder [nTPM]":"19.7","Tissue RNA - heart muscle [nTPM]":"25.3","Tissue RNA - hippocampal formation [nTPM]":"18.6","Tissue RNA - hypothalamus [nTPM]":"21.2","Tissue RNA - kidney [nTPM]":"24.5","Tissue RNA - liver [nTPM]":"117.5","Tissue RNA - lung [nTPM]":"27.0","Tissue RNA - lymph node [nTPM]":"60.9","Tissue RNA - medulla oblongata [nTPM]":"27.9","Tissue RNA - midbrain [nTPM]":"25.6","Tissue RNA - ovary [nTPM]":"30.9","Tissue RNA - pancreas [nTPM]":"90.9","Tissue RNA - parathyroid gland [nTPM]":"35.0","Tissue RNA - pituitary gland [nTPM]":"38.2","Tissue RNA - placenta [nTPM]":"26.2","Tissue RNA - pons [nTPM]":"24.6","Tissue RNA - prostate [nTPM]":"28.5","Tissue RNA - rectum [nTPM]":"29.0","Tissue RNA - retina [nTPM]":"18.7","Tissue RNA - salivary gland [nTPM]":"55.9","Tissue RNA - seminal vesicle [nTPM]":"30.3","Tissue RNA - skeletal muscle [nTPM]":"34.2","Tissue RNA - skin 1 [nTPM]":"29.3","Tissue RNA - small intestine [nTPM]":"39.4","Tissue RNA - smooth muscle [nTPM]":"25.9","Tissue RNA - spinal cord [nTPM]":"22.8","Tissue RNA - spleen [nTPM]":"51.2","Tissue RNA - stomach 1 [nTPM]":"39.4","Tissue RNA - testis [nTPM]":"24.3","Tissue RNA - thalamus [nTPM]":"23.4","Tissue RNA - thymus [nTPM]":"18.3","Tissue RNA - thyroid gland [nTPM]":"43.4","Tissue RNA - tongue [nTPM]":"19.0","Tissue RNA - tonsil [nTPM]":"81.1","Tissue RNA - urinary bladder [nTPM]":"25.8","Tissue RNA - vagina [nTPM]":"24.8","Tissue RNA - white matter [nTPM]":"25.9","Cell RNA - A-431 [nTPM]":"32.4","Cell RNA - A549 [nTPM]":"40.6","Cell RNA - AF22 [nTPM]":"24.0","Cell RNA - AN3-CA [nTPM]":"32.5","Cell RNA - ASC diff [nTPM]":"59.8","Cell RNA - ASC TERT1 [nTPM]":"33.8","Cell RNA - BEWO [nTPM]":"23.8","Cell RNA - BJ [nTPM]":"32.8","Cell RNA - BJ hTERT+ [nTPM]":"33.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"40.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"28.8","Cell RNA - CACO-2 [nTPM]":"22.2","Cell RNA - CAPAN-2 [nTPM]":"55.0","Cell RNA - Daudi [nTPM]":"181.0","Cell RNA - EFO-21 [nTPM]":"43.8","Cell RNA - fHDF\/TERT166 [nTPM]":"42.4","Cell RNA - GAMG [nTPM]":"53.8","Cell RNA - HaCaT [nTPM]":"48.8","Cell RNA - HAP1 [nTPM]":"26.4","Cell RNA - HBEC3-KT [nTPM]":"33.3","Cell RNA - HBF TERT88 [nTPM]":"33.6","Cell RNA - HDLM-2 [nTPM]":"28.4","Cell RNA - HEK 293 [nTPM]":"20.0","Cell RNA - HEL [nTPM]":"28.6","Cell RNA - HeLa [nTPM]":"46.8","Cell RNA - Hep G2 [nTPM]":"50.2","Cell RNA - HHSteC [nTPM]":"72.3","Cell RNA - HL-60 [nTPM]":"43.3","Cell RNA - HMC-1 [nTPM]":"49.6","Cell RNA - HSkMC [nTPM]":"43.3","Cell RNA - hTCEpi [nTPM]":"59.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"36.1","Cell RNA - hTERT-HME1 [nTPM]":"81.0","Cell RNA - hTERT-RPE1 [nTPM]":"36.4","Cell RNA - HUVEC TERT2 [nTPM]":"27.0","Cell RNA - JURKAT [nTPM]":"19.0","Cell RNA - K-562 [nTPM]":"36.4","Cell RNA - Karpas-707 [nTPM]":"90.1","Cell RNA - LHCN-M2 [nTPM]":"24.3","Cell RNA - MCF7 [nTPM]":"47.9","Cell RNA - MOLT-4 [nTPM]":"19.1","Cell RNA - NB-4 [nTPM]":"31.2","Cell RNA - NTERA-2 [nTPM]":"26.1","Cell RNA - OE19 [nTPM]":"33.6","Cell RNA - PC-3 [nTPM]":"28.0","Cell RNA - REH [nTPM]":"31.9","Cell RNA - RH-30 [nTPM]":"20.3","Cell RNA - RPMI-8226 [nTPM]":"74.0","Cell RNA - RPTEC TERT1 [nTPM]":"25.7","Cell RNA - RT4 [nTPM]":"31.5","Cell RNA - SCLC-21H [nTPM]":"15.6","Cell RNA - SH-SY5Y [nTPM]":"32.0","Cell RNA - SiHa [nTPM]":"30.4","Cell RNA - SK-BR-3 [nTPM]":"74.1","Cell RNA - SK-MEL-30 [nTPM]":"53.3","Cell RNA - SuSa [nTPM]":"21.0","Cell RNA - T-47d [nTPM]":"55.4","Cell RNA - THP-1 [nTPM]":"28.2","Cell RNA - TIME [nTPM]":"25.9","Cell RNA - U-138 MG [nTPM]":"28.3","Cell RNA - U-2 OS [nTPM]":"18.6","Cell RNA - U-2197 [nTPM]":"51.2","Cell RNA - U-251 MG [nTPM]":"22.4","Cell RNA - U-266\/70 [nTPM]":"178.1","Cell RNA - U-266\/84 [nTPM]":"134.2","Cell RNA - U-698 [nTPM]":"205.9","Cell RNA - U-87 MG [nTPM]":"38.1","Cell RNA - U-937 [nTPM]":"21.8","Cell RNA - WM-115 [nTPM]":"32.3","Blood RNA - basophil [nTPM]":"16.8","Blood RNA - classical monocyte [nTPM]":"7.4","Blood RNA - eosinophil [nTPM]":"14.0","Blood RNA - gdT-cell [nTPM]":"7.4","Blood RNA - intermediate monocyte [nTPM]":"4.7","Blood RNA - MAIT T-cell [nTPM]":"6.5","Blood RNA - memory B-cell [nTPM]":"21.9","Blood RNA - memory CD4 T-cell [nTPM]":"5.2","Blood RNA - memory CD8 T-cell [nTPM]":"6.9","Blood RNA - myeloid DC [nTPM]":"4.4","Blood RNA - naive B-cell [nTPM]":"22.6","Blood RNA - naive CD4 T-cell [nTPM]":"3.7","Blood RNA - naive CD8 T-cell [nTPM]":"3.9","Blood RNA - neutrophil [nTPM]":"7.0","Blood RNA - NK-cell [nTPM]":"3.5","Blood RNA - non-classical monocyte [nTPM]":"4.7","Blood RNA - plasmacytoid DC [nTPM]":"18.4","Blood RNA - T-reg [nTPM]":"5.3","Blood RNA - total PBMC [nTPM]":"6.6","Brain RNA - amygdala [nTPM]":"19.3","Brain RNA - basal ganglia [nTPM]":"25.6","Brain RNA - cerebellum [nTPM]":"23.2","Brain RNA - cerebral cortex [nTPM]":"21.4","Brain RNA - hippocampal formation [nTPM]":"18.6","Brain RNA - hypothalamus [nTPM]":"21.2","Brain RNA - medulla oblongata [nTPM]":"27.9","Brain RNA - midbrain [nTPM]":"25.6","Brain RNA - pons [nTPM]":"24.6","Brain RNA - spinal cord [nTPM]":"22.8","Brain RNA - thalamus [nTPM]":"23.4","Brain RNA - white matter [nTPM]":"25.9","Single Cell Type RNA - Adipocytes [nTPM]":"11.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.4","Single Cell Type RNA - Astrocytes [nTPM]":"11.1","Single Cell Type RNA - B-cells [nTPM]":"43.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.0","Single Cell Type RNA - Bipolar cells [nTPM]":"10.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"20.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.5","Single Cell Type RNA - dendritic cells [nTPM]":"16.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"13.6","Single Cell Type RNA - Early spermatids [nTPM]":"6.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.2","Single Cell Type RNA - Endothelial cells [nTPM]":"11.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"13.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"16.5","Single Cell Type RNA - Fibroblasts [nTPM]":"14.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"22.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"10.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.0","Single Cell Type RNA - Hepatocytes [nTPM]":"72.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.1","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"33.6","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"15.3","Single Cell Type RNA - Langerhans cells [nTPM]":"13.2","Single Cell Type RNA - Late spermatids [nTPM]":"4.1","Single Cell Type RNA - Leydig cells [nTPM]":"20.5","Single Cell Type RNA - Macrophages [nTPM]":"10.8","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"10.5","Single Cell Type RNA - Muller glia cells [nTPM]":"11.0","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.2","Single Cell Type RNA - Paneth cells [nTPM]":"11.7","Single Cell Type RNA - Peritubular cells [nTPM]":"13.2","Single Cell Type RNA - Plasma cells [nTPM]":"90.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.7","Single Cell Type RNA - Spermatocytes [nTPM]":"19.3","Single Cell Type RNA - Spermatogonia [nTPM]":"13.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"42.8","Single Cell Type RNA - T-cells [nTPM]":"11.7","Single Cell Type RNA - Theca cells [nTPM]":"13.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.6","Single Cell Type RNA - Urothelial cells [nTPM]":"13.8"},{"Gene":"TACR3","Gene synonym":["NK3R","NKR","TAC3R"],"Ensembl":"ENSG00000169836","Gene description":"Tachykinin receptor 3","Uniprot":["P29371"],"Chromosome":"4","Position":"103586031-103719985","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","Hypogonadotropic hypogonadism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"8.4","retina":"2.7","urinary bladder":"1.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Bipolar cells":"13.1","Excitatory neurons":"6.7","Extravillous trophoblasts":"4.5","Oligodendrocytes":"10.5","Skeletal myocytes":"11.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"pons":"8.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"BEWO":"7.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009418"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA009418":"AB_1857727"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"2.7","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"2.4","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"1.4","Tissue RNA - midbrain [nTPM]":"1.5","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"8.4","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"2.7","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"1.7","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.9","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"1.9","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"1.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"7.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.6","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.7","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"2.4","Brain RNA - medulla oblongata [nTPM]":"1.4","Brain RNA - midbrain [nTPM]":"1.5","Brain RNA - pons [nTPM]":"8.4","Brain RNA - spinal cord [nTPM]":"1.7","Brain RNA - thalamus [nTPM]":"0.9","Brain RNA - white matter [nTPM]":"1.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"13.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.5","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"TAF1","Gene synonym":["BA2R","CCG1","CCGS","DYT3","DYT3\/TAF1","KAT4","NSCL2","TAF2A","TAFII250"],"Ensembl":"ENSG00000147133","Gene description":"TATA-box binding protein associated factor 1","Uniprot":["P21675"],"Chromosome":"X","Position":"71366264-71532374","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transcription factors"],"Biological process":["Cell cycle","Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Acyltransferase","DNA-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Dystonia","Mental retardation","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"81.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001075","CAB016283"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB016283":"AB_671202","HPA001075":"AB_1080179"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.54e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.03e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.9","Tissue RNA - adrenal gland [nTPM]":"8.6","Tissue RNA - amygdala [nTPM]":"10.3","Tissue RNA - appendix [nTPM]":"11.4","Tissue RNA - basal ganglia [nTPM]":"12.7","Tissue RNA - bone marrow [nTPM]":"12.8","Tissue RNA - breast [nTPM]":"12.3","Tissue RNA - cerebellum [nTPM]":"13.7","Tissue RNA - cerebral cortex [nTPM]":"11.1","Tissue RNA - cervix [nTPM]":"11.1","Tissue RNA - choroid plexus [nTPM]":"10.2","Tissue RNA - colon [nTPM]":"10.0","Tissue RNA - duodenum [nTPM]":"6.6","Tissue RNA - endometrium 1 [nTPM]":"13.8","Tissue RNA - epididymis [nTPM]":"12.9","Tissue RNA - esophagus [nTPM]":"7.5","Tissue RNA - fallopian tube [nTPM]":"11.1","Tissue RNA - gallbladder [nTPM]":"7.8","Tissue RNA - heart muscle [nTPM]":"7.0","Tissue RNA - hippocampal formation [nTPM]":"9.3","Tissue RNA - hypothalamus [nTPM]":"14.1","Tissue RNA - kidney [nTPM]":"7.5","Tissue RNA - liver [nTPM]":"7.8","Tissue RNA - lung [nTPM]":"9.1","Tissue RNA - lymph node [nTPM]":"14.1","Tissue RNA - medulla oblongata [nTPM]":"11.5","Tissue RNA - midbrain [nTPM]":"11.3","Tissue RNA - ovary [nTPM]":"14.4","Tissue RNA - pancreas [nTPM]":"9.8","Tissue RNA - parathyroid gland [nTPM]":"12.2","Tissue RNA - pituitary gland [nTPM]":"8.4","Tissue RNA - placenta [nTPM]":"10.0","Tissue RNA - pons [nTPM]":"10.9","Tissue RNA - prostate [nTPM]":"10.0","Tissue RNA - rectum [nTPM]":"10.0","Tissue RNA - retina [nTPM]":"27.3","Tissue RNA - salivary gland [nTPM]":"7.7","Tissue RNA - seminal vesicle [nTPM]":"10.1","Tissue RNA - skeletal muscle [nTPM]":"10.5","Tissue RNA - skin 1 [nTPM]":"13.3","Tissue RNA - small intestine [nTPM]":"9.3","Tissue RNA - smooth muscle [nTPM]":"10.9","Tissue RNA - spinal cord [nTPM]":"8.2","Tissue RNA - spleen [nTPM]":"15.4","Tissue RNA - stomach 1 [nTPM]":"10.6","Tissue RNA - testis [nTPM]":"7.2","Tissue RNA - thalamus [nTPM]":"12.5","Tissue RNA - thymus [nTPM]":"14.8","Tissue RNA - thyroid gland [nTPM]":"12.7","Tissue RNA - tongue [nTPM]":"10.3","Tissue RNA - tonsil [nTPM]":"12.4","Tissue RNA - urinary bladder [nTPM]":"9.2","Tissue RNA - vagina [nTPM]":"8.6","Tissue RNA - white matter [nTPM]":"16.8","Cell RNA - A-431 [nTPM]":"18.6","Cell RNA - A549 [nTPM]":"15.9","Cell RNA - AF22 [nTPM]":"18.2","Cell RNA - AN3-CA [nTPM]":"12.4","Cell RNA - ASC diff [nTPM]":"14.6","Cell RNA - ASC TERT1 [nTPM]":"23.2","Cell RNA - BEWO [nTPM]":"11.0","Cell RNA - BJ [nTPM]":"13.3","Cell RNA - BJ hTERT+ [nTPM]":"12.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.1","Cell RNA - CACO-2 [nTPM]":"12.3","Cell RNA - CAPAN-2 [nTPM]":"11.3","Cell RNA - Daudi [nTPM]":"17.6","Cell RNA - EFO-21 [nTPM]":"11.5","Cell RNA - fHDF\/TERT166 [nTPM]":"14.9","Cell RNA - GAMG [nTPM]":"12.3","Cell RNA - HaCaT [nTPM]":"17.5","Cell RNA - HAP1 [nTPM]":"24.1","Cell RNA - HBEC3-KT [nTPM]":"11.0","Cell RNA - HBF TERT88 [nTPM]":"17.0","Cell RNA - HDLM-2 [nTPM]":"11.2","Cell RNA - HEK 293 [nTPM]":"21.9","Cell RNA - HEL [nTPM]":"20.1","Cell RNA - HeLa [nTPM]":"22.1","Cell RNA - Hep G2 [nTPM]":"13.1","Cell RNA - HHSteC [nTPM]":"11.1","Cell RNA - HL-60 [nTPM]":"39.7","Cell RNA - HMC-1 [nTPM]":"19.4","Cell RNA - HSkMC [nTPM]":"14.1","Cell RNA - hTCEpi [nTPM]":"11.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.2","Cell RNA - hTERT-HME1 [nTPM]":"27.2","Cell RNA - hTERT-RPE1 [nTPM]":"12.8","Cell RNA - HUVEC TERT2 [nTPM]":"14.7","Cell RNA - JURKAT [nTPM]":"13.2","Cell RNA - K-562 [nTPM]":"28.2","Cell RNA - Karpas-707 [nTPM]":"41.1","Cell RNA - LHCN-M2 [nTPM]":"14.4","Cell RNA - MCF7 [nTPM]":"14.5","Cell RNA - MOLT-4 [nTPM]":"22.4","Cell RNA - NB-4 [nTPM]":"25.4","Cell RNA - NTERA-2 [nTPM]":"20.9","Cell RNA - OE19 [nTPM]":"23.5","Cell RNA - PC-3 [nTPM]":"20.8","Cell RNA - REH [nTPM]":"19.8","Cell RNA - RH-30 [nTPM]":"35.8","Cell RNA - RPMI-8226 [nTPM]":"21.6","Cell RNA - RPTEC TERT1 [nTPM]":"11.1","Cell RNA - RT4 [nTPM]":"25.0","Cell RNA - SCLC-21H [nTPM]":"9.0","Cell RNA - SH-SY5Y [nTPM]":"14.5","Cell RNA - SiHa [nTPM]":"37.7","Cell RNA - SK-BR-3 [nTPM]":"13.6","Cell RNA - SK-MEL-30 [nTPM]":"18.7","Cell RNA - SuSa [nTPM]":"14.3","Cell RNA - T-47d [nTPM]":"9.6","Cell RNA - THP-1 [nTPM]":"22.9","Cell RNA - TIME [nTPM]":"18.6","Cell RNA - U-138 MG [nTPM]":"16.5","Cell RNA - U-2 OS [nTPM]":"14.2","Cell RNA - U-2197 [nTPM]":"13.4","Cell RNA - U-251 MG [nTPM]":"9.7","Cell RNA - U-266\/70 [nTPM]":"17.5","Cell RNA - U-266\/84 [nTPM]":"17.4","Cell RNA - U-698 [nTPM]":"21.4","Cell RNA - U-87 MG [nTPM]":"9.0","Cell RNA - U-937 [nTPM]":"33.2","Cell RNA - WM-115 [nTPM]":"12.5","Blood RNA - basophil [nTPM]":"1.6","Blood RNA - classical monocyte [nTPM]":"1.4","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"1.4","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"1.3","Blood RNA - memory B-cell [nTPM]":"1.0","Blood RNA - memory CD4 T-cell [nTPM]":"1.4","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"1.5","Blood RNA - naive CD4 T-cell [nTPM]":"1.6","Blood RNA - naive CD8 T-cell [nTPM]":"1.8","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"1.6","Blood RNA - plasmacytoid DC [nTPM]":"1.4","Blood RNA - T-reg [nTPM]":"1.0","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"10.3","Brain RNA - basal ganglia [nTPM]":"12.7","Brain RNA - cerebellum [nTPM]":"13.7","Brain RNA - cerebral cortex [nTPM]":"11.1","Brain RNA - hippocampal formation [nTPM]":"9.3","Brain RNA - hypothalamus [nTPM]":"14.1","Brain RNA - medulla oblongata [nTPM]":"11.5","Brain RNA - midbrain [nTPM]":"11.3","Brain RNA - pons [nTPM]":"10.9","Brain RNA - spinal cord [nTPM]":"8.2","Brain RNA - thalamus [nTPM]":"12.5","Brain RNA - white matter [nTPM]":"16.8","Single Cell Type RNA - Adipocytes [nTPM]":"26.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.7","Single Cell Type RNA - Astrocytes [nTPM]":"44.7","Single Cell Type RNA - B-cells [nTPM]":"21.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.2","Single Cell Type RNA - Bipolar cells [nTPM]":"37.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"23.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"81.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.6","Single Cell Type RNA - dendritic cells [nTPM]":"21.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.3","Single Cell Type RNA - Early spermatids [nTPM]":"2.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.4","Single Cell Type RNA - Endothelial cells [nTPM]":"24.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.4","Single Cell Type RNA - Erythroid cells [nTPM]":"28.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"54.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.9","Single Cell Type RNA - Fibroblasts [nTPM]":"17.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.9","Single Cell Type RNA - granulocytes [nTPM]":"23.4","Single Cell Type RNA - Granulosa cells [nTPM]":"23.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.9","Single Cell Type RNA - Hepatocytes [nTPM]":"12.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.8","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"52.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.6","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"16.2","Single Cell Type RNA - Langerhans cells [nTPM]":"20.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.6","Single Cell Type RNA - Leydig cells [nTPM]":"22.1","Single Cell Type RNA - Macrophages [nTPM]":"20.4","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"47.8","Single Cell Type RNA - monocytes [nTPM]":"23.9","Single Cell Type RNA - Muller glia cells [nTPM]":"17.0","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"49.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"79.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.6","Single Cell Type RNA - Paneth cells [nTPM]":"13.3","Single Cell Type RNA - Peritubular cells [nTPM]":"22.2","Single Cell Type RNA - Plasma cells [nTPM]":"18.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"67.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.0","Single Cell Type RNA - Spermatocytes [nTPM]":"9.3","Single Cell Type RNA - Spermatogonia [nTPM]":"10.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.7","Single Cell Type RNA - T-cells [nTPM]":"23.8","Single Cell Type RNA - Theca cells [nTPM]":"25.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.6","Single Cell Type RNA - Urothelial cells [nTPM]":"9.6"},{"Gene":"TALDO1","Gene synonym":[],"Ensembl":"ENSG00000177156","Gene description":"Transaldolase 1","Uniprot":["P37837"],"Chromosome":"11","Position":"747415-765012","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Pentose shunt"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"monocytes":"820.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"2870.4","neutrophil":"3726.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048089"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"29000000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 3: Monocytes - Immune response regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA048089":"AB_2680260"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.65e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.29e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-3"},"Tissue RNA - adipose tissue [nTPM]":"139.5","Tissue RNA - adrenal gland [nTPM]":"80.7","Tissue RNA - amygdala [nTPM]":"108.0","Tissue RNA - appendix [nTPM]":"121.8","Tissue RNA - basal ganglia [nTPM]":"128.8","Tissue RNA - bone marrow [nTPM]":"464.8","Tissue RNA - breast [nTPM]":"121.0","Tissue RNA - cerebellum [nTPM]":"129.3","Tissue RNA - cerebral cortex [nTPM]":"119.3","Tissue RNA - cervix [nTPM]":"101.9","Tissue RNA - choroid plexus [nTPM]":"105.2","Tissue RNA - colon [nTPM]":"99.6","Tissue RNA - duodenum [nTPM]":"116.0","Tissue RNA - endometrium 1 [nTPM]":"68.4","Tissue RNA - epididymis [nTPM]":"66.4","Tissue RNA - esophagus [nTPM]":"330.6","Tissue RNA - fallopian tube [nTPM]":"79.1","Tissue RNA - gallbladder [nTPM]":"100.0","Tissue RNA - heart muscle [nTPM]":"95.5","Tissue RNA - hippocampal formation [nTPM]":"108.0","Tissue RNA - hypothalamus [nTPM]":"113.8","Tissue RNA - kidney [nTPM]":"111.6","Tissue RNA - liver [nTPM]":"136.2","Tissue RNA - lung [nTPM]":"109.1","Tissue RNA - lymph node [nTPM]":"107.8","Tissue RNA - medulla oblongata [nTPM]":"135.8","Tissue RNA - midbrain [nTPM]":"119.3","Tissue RNA - ovary [nTPM]":"77.0","Tissue RNA - pancreas [nTPM]":"107.5","Tissue RNA - parathyroid gland [nTPM]":"49.3","Tissue RNA - pituitary gland [nTPM]":"53.0","Tissue RNA - placenta [nTPM]":"88.0","Tissue RNA - pons [nTPM]":"130.0","Tissue RNA - prostate [nTPM]":"91.9","Tissue RNA - rectum [nTPM]":"78.4","Tissue RNA - retina [nTPM]":"34.2","Tissue RNA - salivary gland [nTPM]":"132.8","Tissue RNA - seminal vesicle [nTPM]":"60.1","Tissue RNA - skeletal muscle [nTPM]":"120.7","Tissue RNA - skin 1 [nTPM]":"132.7","Tissue RNA - small intestine [nTPM]":"101.0","Tissue RNA - smooth muscle [nTPM]":"60.8","Tissue RNA - spinal cord [nTPM]":"124.0","Tissue RNA - spleen [nTPM]":"152.6","Tissue RNA - stomach 1 [nTPM]":"132.5","Tissue RNA - testis [nTPM]":"40.4","Tissue RNA - thalamus [nTPM]":"120.1","Tissue RNA - thymus [nTPM]":"109.9","Tissue RNA - thyroid gland [nTPM]":"140.3","Tissue RNA - tongue [nTPM]":"107.1","Tissue RNA - tonsil [nTPM]":"115.8","Tissue RNA - urinary bladder [nTPM]":"160.8","Tissue RNA - vagina [nTPM]":"142.1","Tissue RNA - white matter [nTPM]":"148.2","Cell RNA - A-431 [nTPM]":"331.0","Cell RNA - A549 [nTPM]":"405.5","Cell RNA - AF22 [nTPM]":"115.4","Cell RNA - AN3-CA [nTPM]":"218.1","Cell RNA - ASC diff [nTPM]":"235.8","Cell RNA - ASC TERT1 [nTPM]":"136.5","Cell RNA - BEWO [nTPM]":"338.0","Cell RNA - BJ [nTPM]":"242.2","Cell RNA - BJ hTERT+ [nTPM]":"313.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"238.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"194.5","Cell RNA - CACO-2 [nTPM]":"176.6","Cell RNA - CAPAN-2 [nTPM]":"694.8","Cell RNA - Daudi [nTPM]":"179.5","Cell RNA - EFO-21 [nTPM]":"323.1","Cell RNA - fHDF\/TERT166 [nTPM]":"324.7","Cell RNA - GAMG [nTPM]":"181.9","Cell RNA - HaCaT [nTPM]":"345.5","Cell RNA - HAP1 [nTPM]":"185.6","Cell RNA - HBEC3-KT [nTPM]":"263.5","Cell RNA - HBF TERT88 [nTPM]":"122.8","Cell RNA - HDLM-2 [nTPM]":"238.9","Cell RNA - HEK 293 [nTPM]":"372.5","Cell RNA - HEL [nTPM]":"310.9","Cell RNA - HeLa [nTPM]":"146.0","Cell RNA - Hep G2 [nTPM]":"616.4","Cell RNA - HHSteC [nTPM]":"250.3","Cell RNA - HL-60 [nTPM]":"498.4","Cell RNA - HMC-1 [nTPM]":"449.0","Cell RNA - HSkMC [nTPM]":"112.0","Cell RNA - hTCEpi [nTPM]":"210.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"159.6","Cell RNA - hTERT-HME1 [nTPM]":"129.0","Cell RNA - hTERT-RPE1 [nTPM]":"170.4","Cell RNA - HUVEC TERT2 [nTPM]":"331.6","Cell RNA - JURKAT [nTPM]":"224.0","Cell RNA - K-562 [nTPM]":"413.5","Cell RNA - Karpas-707 [nTPM]":"294.3","Cell RNA - LHCN-M2 [nTPM]":"224.5","Cell RNA - MCF7 [nTPM]":"318.0","Cell RNA - MOLT-4 [nTPM]":"296.4","Cell RNA - NB-4 [nTPM]":"601.2","Cell RNA - NTERA-2 [nTPM]":"183.9","Cell RNA - OE19 [nTPM]":"478.9","Cell RNA - PC-3 [nTPM]":"326.0","Cell RNA - REH [nTPM]":"243.5","Cell RNA - RH-30 [nTPM]":"131.5","Cell RNA - RPMI-8226 [nTPM]":"656.4","Cell RNA - RPTEC TERT1 [nTPM]":"437.9","Cell RNA - RT4 [nTPM]":"185.4","Cell RNA - SCLC-21H [nTPM]":"284.2","Cell RNA - SH-SY5Y [nTPM]":"100.1","Cell RNA - SiHa [nTPM]":"224.9","Cell RNA - SK-BR-3 [nTPM]":"466.1","Cell RNA - SK-MEL-30 [nTPM]":"243.3","Cell RNA - SuSa [nTPM]":"102.4","Cell RNA - T-47d [nTPM]":"220.0","Cell RNA - THP-1 [nTPM]":"383.9","Cell RNA - TIME [nTPM]":"434.1","Cell RNA - U-138 MG [nTPM]":"107.9","Cell RNA - U-2 OS [nTPM]":"99.5","Cell RNA - U-2197 [nTPM]":"86.0","Cell RNA - U-251 MG [nTPM]":"232.9","Cell RNA - U-266\/70 [nTPM]":"122.9","Cell RNA - U-266\/84 [nTPM]":"132.1","Cell RNA - U-698 [nTPM]":"223.5","Cell RNA - U-87 MG [nTPM]":"238.5","Cell RNA - U-937 [nTPM]":"440.5","Cell RNA - WM-115 [nTPM]":"444.7","Blood RNA - basophil [nTPM]":"1456.7","Blood RNA - classical monocyte [nTPM]":"1203.5","Blood RNA - eosinophil [nTPM]":"2870.4","Blood RNA - gdT-cell [nTPM]":"94.1","Blood RNA - intermediate monocyte [nTPM]":"432.7","Blood RNA - MAIT T-cell [nTPM]":"102.3","Blood RNA - memory B-cell [nTPM]":"145.5","Blood RNA - memory CD4 T-cell [nTPM]":"125.7","Blood RNA - memory CD8 T-cell [nTPM]":"115.5","Blood RNA - myeloid DC [nTPM]":"654.2","Blood RNA - naive B-cell [nTPM]":"127.2","Blood RNA - naive CD4 T-cell [nTPM]":"100.9","Blood RNA - naive CD8 T-cell [nTPM]":"94.9","Blood RNA - neutrophil [nTPM]":"3726.6","Blood RNA - NK-cell [nTPM]":"112.2","Blood RNA - non-classical monocyte [nTPM]":"457.8","Blood RNA - plasmacytoid DC [nTPM]":"267.0","Blood RNA - T-reg [nTPM]":"192.7","Blood RNA - total PBMC [nTPM]":"1066.0","Brain RNA - amygdala [nTPM]":"108.0","Brain RNA - basal ganglia [nTPM]":"128.8","Brain RNA - cerebellum [nTPM]":"129.3","Brain RNA - cerebral cortex [nTPM]":"119.3","Brain RNA - hippocampal formation [nTPM]":"108.0","Brain RNA - hypothalamus [nTPM]":"113.8","Brain RNA - medulla oblongata [nTPM]":"135.8","Brain RNA - midbrain [nTPM]":"119.3","Brain RNA - pons [nTPM]":"130.0","Brain RNA - spinal cord [nTPM]":"124.0","Brain RNA - thalamus [nTPM]":"120.1","Brain RNA - white matter [nTPM]":"148.2","Single Cell Type RNA - Adipocytes [nTPM]":"90.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"141.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"117.2","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"91.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"73.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"199.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"354.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"61.5","Single Cell Type RNA - Bipolar cells [nTPM]":"50.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"113.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"122.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"46.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"100.1","Single Cell Type RNA - Club cells [nTPM]":"253.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"150.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"419.8","Single Cell Type RNA - dendritic cells [nTPM]":"83.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"151.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"250.5","Single Cell Type RNA - Ductal cells [nTPM]":"230.4","Single Cell Type RNA - Early spermatids [nTPM]":"82.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"156.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"85.4","Single Cell Type RNA - Endothelial cells [nTPM]":"85.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"101.5","Single Cell Type RNA - Erythroid cells [nTPM]":"507.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"272.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"427.6","Single Cell Type RNA - Fibroblasts [nTPM]":"97.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"144.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"216.7","Single Cell Type RNA - granulocytes [nTPM]":"161.4","Single Cell Type RNA - Granulosa cells [nTPM]":"86.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"93.5","Single Cell Type RNA - Hepatocytes [nTPM]":"149.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"418.3","Single Cell Type RNA - Horizontal cells [nTPM]":"50.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"186.0","Single Cell Type RNA - Ionocytes [nTPM]":"268.5","Single Cell Type RNA - Kupffer cells [nTPM]":"271.8","Single Cell Type RNA - Langerhans cells [nTPM]":"169.4","Single Cell Type RNA - Late spermatids [nTPM]":"21.2","Single Cell Type RNA - Leydig cells [nTPM]":"117.8","Single Cell Type RNA - Macrophages [nTPM]":"352.8","Single Cell Type RNA - Melanocytes [nTPM]":"140.5","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"820.0","Single Cell Type RNA - Muller glia cells [nTPM]":"142.1","Single Cell Type RNA - NK-cells [nTPM]":"84.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"54.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"257.6","Single Cell Type RNA - Paneth cells [nTPM]":"200.3","Single Cell Type RNA - Peritubular cells [nTPM]":"104.2","Single Cell Type RNA - Plasma cells [nTPM]":"129.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"361.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"197.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"309.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"232.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"61.7","Single Cell Type RNA - Sertoli cells [nTPM]":"72.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"59.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"115.0","Single Cell Type RNA - Spermatocytes [nTPM]":"143.2","Single Cell Type RNA - Spermatogonia [nTPM]":"140.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"257.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"83.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"526.6","Single Cell Type RNA - T-cells [nTPM]":"86.8","Single Cell Type RNA - Theca cells [nTPM]":"77.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"215.1","Single Cell Type RNA - Urothelial cells [nTPM]":"342.6"},{"Gene":"TAP1","Gene synonym":["ABCB2","D6S114E","PSF1","RING4"],"Ensembl":"ENSG00000168394","Gene description":"Transporter 1, ATP binding cassette subfamily B member","Uniprot":["Q03518"],"Chromosome":"6","Position":"32845209-32853816","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity","Peptide transport","Protein transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"126.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009516","HPA072354"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Centriolar satellite"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Endoplasmic reticulum","Centriolar satellite"],"Subcellular additional location":null,"Antibody RRID":{"CAB009516":"AB_2303048","HPA072354":"AB_2686513"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.01e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.07e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.58e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Tissue RNA - adipose tissue [nTPM]":"28.4","Tissue RNA - adrenal gland [nTPM]":"24.9","Tissue RNA - amygdala [nTPM]":"16.1","Tissue RNA - appendix [nTPM]":"50.1","Tissue RNA - basal ganglia [nTPM]":"16.2","Tissue RNA - bone marrow [nTPM]":"13.7","Tissue RNA - breast [nTPM]":"20.7","Tissue RNA - cerebellum [nTPM]":"15.8","Tissue RNA - cerebral cortex [nTPM]":"20.3","Tissue RNA - cervix [nTPM]":"21.6","Tissue RNA - choroid plexus [nTPM]":"16.2","Tissue RNA - colon [nTPM]":"30.3","Tissue RNA - duodenum [nTPM]":"36.0","Tissue RNA - endometrium 1 [nTPM]":"20.5","Tissue RNA - epididymis [nTPM]":"2.5","Tissue RNA - esophagus [nTPM]":"31.6","Tissue RNA - fallopian tube [nTPM]":"17.8","Tissue RNA - gallbladder [nTPM]":"12.7","Tissue RNA - heart muscle [nTPM]":"25.4","Tissue RNA - hippocampal formation [nTPM]":"14.7","Tissue RNA - hypothalamus [nTPM]":"16.2","Tissue RNA - kidney [nTPM]":"21.8","Tissue RNA - liver [nTPM]":"19.3","Tissue RNA - lung [nTPM]":"52.7","Tissue RNA - lymph node [nTPM]":"50.0","Tissue RNA - medulla oblongata [nTPM]":"24.0","Tissue RNA - midbrain [nTPM]":"16.1","Tissue RNA - ovary [nTPM]":"12.1","Tissue RNA - pancreas [nTPM]":"14.5","Tissue RNA - parathyroid gland [nTPM]":"7.0","Tissue RNA - pituitary gland [nTPM]":"11.6","Tissue RNA - placenta [nTPM]":"12.1","Tissue RNA - pons [nTPM]":"21.2","Tissue RNA - prostate [nTPM]":"21.9","Tissue RNA - rectum [nTPM]":"12.5","Tissue RNA - retina [nTPM]":"1.7","Tissue RNA - salivary gland [nTPM]":"25.9","Tissue RNA - seminal vesicle [nTPM]":"7.0","Tissue RNA - skeletal muscle [nTPM]":"16.3","Tissue RNA - skin 1 [nTPM]":"51.2","Tissue RNA - small intestine [nTPM]":"42.6","Tissue RNA - smooth muscle [nTPM]":"11.5","Tissue RNA - spinal cord [nTPM]":"18.6","Tissue RNA - spleen [nTPM]":"73.0","Tissue RNA - stomach 1 [nTPM]":"33.4","Tissue RNA - testis [nTPM]":"11.5","Tissue RNA - thalamus [nTPM]":"19.4","Tissue RNA - thymus [nTPM]":"25.5","Tissue RNA - thyroid gland [nTPM]":"17.0","Tissue RNA - tongue [nTPM]":"7.4","Tissue RNA - tonsil [nTPM]":"21.3","Tissue RNA - urinary bladder [nTPM]":"23.9","Tissue RNA - vagina [nTPM]":"24.4","Tissue RNA - white matter [nTPM]":"17.4","Cell RNA - A-431 [nTPM]":"22.9","Cell RNA - A549 [nTPM]":"13.7","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"16.1","Cell RNA - ASC diff [nTPM]":"8.8","Cell RNA - ASC TERT1 [nTPM]":"11.4","Cell RNA - BEWO [nTPM]":"126.2","Cell RNA - BJ [nTPM]":"8.1","Cell RNA - BJ hTERT+ [nTPM]":"34.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"59.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"86.5","Cell RNA - CACO-2 [nTPM]":"2.0","Cell RNA - CAPAN-2 [nTPM]":"27.3","Cell RNA - Daudi [nTPM]":"41.8","Cell RNA - EFO-21 [nTPM]":"25.0","Cell RNA - fHDF\/TERT166 [nTPM]":"12.6","Cell RNA - GAMG [nTPM]":"48.9","Cell RNA - HaCaT [nTPM]":"45.8","Cell RNA - HAP1 [nTPM]":"4.5","Cell RNA - HBEC3-KT [nTPM]":"20.6","Cell RNA - HBF TERT88 [nTPM]":"5.3","Cell RNA - HDLM-2 [nTPM]":"81.0","Cell RNA - HEK 293 [nTPM]":"6.1","Cell RNA - HEL [nTPM]":"26.5","Cell RNA - HeLa [nTPM]":"4.1","Cell RNA - Hep G2 [nTPM]":"10.8","Cell RNA - HHSteC [nTPM]":"42.3","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"17.5","Cell RNA - HSkMC [nTPM]":"15.0","Cell RNA - hTCEpi [nTPM]":"17.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"17.1","Cell RNA - hTERT-HME1 [nTPM]":"10.4","Cell RNA - hTERT-RPE1 [nTPM]":"8.6","Cell RNA - HUVEC TERT2 [nTPM]":"15.4","Cell RNA - JURKAT [nTPM]":"8.4","Cell RNA - K-562 [nTPM]":"1.9","Cell RNA - Karpas-707 [nTPM]":"55.0","Cell RNA - LHCN-M2 [nTPM]":"10.6","Cell RNA - MCF7 [nTPM]":"10.5","Cell RNA - MOLT-4 [nTPM]":"17.7","Cell RNA - NB-4 [nTPM]":"27.4","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"3.1","Cell RNA - PC-3 [nTPM]":"11.1","Cell RNA - REH [nTPM]":"47.6","Cell RNA - RH-30 [nTPM]":"5.2","Cell RNA - RPMI-8226 [nTPM]":"32.8","Cell RNA - RPTEC TERT1 [nTPM]":"25.0","Cell RNA - RT4 [nTPM]":"10.5","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"1.2","Cell RNA - SiHa [nTPM]":"6.7","Cell RNA - SK-BR-3 [nTPM]":"38.0","Cell RNA - SK-MEL-30 [nTPM]":"33.4","Cell RNA - SuSa [nTPM]":"1.7","Cell RNA - T-47d [nTPM]":"30.9","Cell RNA - THP-1 [nTPM]":"37.4","Cell RNA - TIME [nTPM]":"9.7","Cell RNA - U-138 MG [nTPM]":"21.5","Cell RNA - U-2 OS [nTPM]":"8.1","Cell RNA - U-2197 [nTPM]":"53.1","Cell RNA - U-251 MG [nTPM]":"11.4","Cell RNA - U-266\/70 [nTPM]":"59.9","Cell RNA - U-266\/84 [nTPM]":"82.6","Cell RNA - U-698 [nTPM]":"12.6","Cell RNA - U-87 MG [nTPM]":"16.6","Cell RNA - U-937 [nTPM]":"16.6","Cell RNA - WM-115 [nTPM]":"16.4","Blood RNA - basophil [nTPM]":"176.8","Blood RNA - classical monocyte [nTPM]":"99.5","Blood RNA - eosinophil [nTPM]":"270.1","Blood RNA - gdT-cell [nTPM]":"155.8","Blood RNA - intermediate monocyte [nTPM]":"101.6","Blood RNA - MAIT T-cell [nTPM]":"133.8","Blood RNA - memory B-cell [nTPM]":"137.3","Blood RNA - memory CD4 T-cell [nTPM]":"125.2","Blood RNA - memory CD8 T-cell [nTPM]":"153.7","Blood RNA - myeloid DC [nTPM]":"95.0","Blood RNA - naive B-cell [nTPM]":"107.5","Blood RNA - naive CD4 T-cell [nTPM]":"120.9","Blood RNA - naive CD8 T-cell [nTPM]":"124.6","Blood RNA - neutrophil [nTPM]":"295.6","Blood RNA - NK-cell [nTPM]":"132.9","Blood RNA - non-classical monocyte [nTPM]":"94.6","Blood RNA - plasmacytoid DC [nTPM]":"94.8","Blood RNA - T-reg [nTPM]":"213.8","Blood RNA - total PBMC [nTPM]":"221.2","Brain RNA - amygdala [nTPM]":"16.1","Brain RNA - basal ganglia [nTPM]":"16.2","Brain RNA - cerebellum [nTPM]":"15.8","Brain RNA - cerebral cortex [nTPM]":"20.3","Brain RNA - hippocampal formation [nTPM]":"14.7","Brain RNA - hypothalamus [nTPM]":"16.2","Brain RNA - medulla oblongata [nTPM]":"24.0","Brain RNA - midbrain [nTPM]":"16.1","Brain RNA - pons [nTPM]":"21.2","Brain RNA - spinal cord [nTPM]":"18.6","Brain RNA - thalamus [nTPM]":"19.4","Brain RNA - white matter [nTPM]":"17.4","Single Cell Type RNA - Adipocytes [nTPM]":"72.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"24.0","Single Cell Type RNA - Astrocytes [nTPM]":"9.1","Single Cell Type RNA - B-cells [nTPM]":"62.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"74.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"47.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"54.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"27.3","Single Cell Type RNA - Bipolar cells [nTPM]":"4.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"33.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.6","Single Cell Type RNA - dendritic cells [nTPM]":"108.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"78.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"81.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"31.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"39.3","Single Cell Type RNA - Endothelial cells [nTPM]":"63.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.8","Single Cell Type RNA - Erythroid cells [nTPM]":"12.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"75.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"95.0","Single Cell Type RNA - Fibroblasts [nTPM]":"26.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"42.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"77.9","Single Cell Type RNA - granulocytes [nTPM]":"26.6","Single Cell Type RNA - Granulosa cells [nTPM]":"13.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"27.1","Single Cell Type RNA - Hepatocytes [nTPM]":"11.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"45.9","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"55.9","Single Cell Type RNA - Ionocytes [nTPM]":"57.0","Single Cell Type RNA - Kupffer cells [nTPM]":"31.9","Single Cell Type RNA - Langerhans cells [nTPM]":"90.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"13.1","Single Cell Type RNA - Macrophages [nTPM]":"43.9","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"115.9","Single Cell Type RNA - Muller glia cells [nTPM]":"25.1","Single Cell Type RNA - NK-cells [nTPM]":"149.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"91.3","Single Cell Type RNA - Paneth cells [nTPM]":"38.8","Single Cell Type RNA - Peritubular cells [nTPM]":"10.5","Single Cell Type RNA - Plasma cells [nTPM]":"84.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"70.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"84.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.8","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"76.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.8","Single Cell Type RNA - T-cells [nTPM]":"92.3","Single Cell Type RNA - Theca cells [nTPM]":"18.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"54.5","Single Cell Type RNA - Urothelial cells [nTPM]":"52.1"},{"Gene":"TAP2","Gene synonym":["ABCB3","D6S217E","PSF2","RING11"],"Ensembl":"ENSG00000204267","Gene description":"Transporter 2, ATP binding cassette subfamily B member","Uniprot":["Q03519"],"Chromosome":"6","Position":"32821833-32838770","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity","Peptide transport","Protein transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"monocytes":"69.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HBEC3-KT":"61.4","U-251 MG":"52.0"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001312"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Nuclear speckles"],"Antibody RRID":{"HPA001312":"AB_1080206"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.51e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.22e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Tissue RNA - adipose tissue [nTPM]":"17.1","Tissue RNA - adrenal gland [nTPM]":"11.7","Tissue RNA - amygdala [nTPM]":"1.0","Tissue RNA - appendix [nTPM]":"4.3","Tissue RNA - basal ganglia [nTPM]":"1.0","Tissue RNA - bone marrow [nTPM]":"8.8","Tissue RNA - breast [nTPM]":"14.7","Tissue RNA - cerebellum [nTPM]":"0.8","Tissue RNA - cerebral cortex [nTPM]":"1.2","Tissue RNA - cervix [nTPM]":"16.3","Tissue RNA - choroid plexus [nTPM]":"0.5","Tissue RNA - colon [nTPM]":"14.6","Tissue RNA - duodenum [nTPM]":"10.2","Tissue RNA - endometrium 1 [nTPM]":"13.7","Tissue RNA - epididymis [nTPM]":"1.1","Tissue RNA - esophagus [nTPM]":"26.0","Tissue RNA - fallopian tube [nTPM]":"11.9","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"14.4","Tissue RNA - hippocampal formation [nTPM]":"1.2","Tissue RNA - hypothalamus [nTPM]":"2.0","Tissue RNA - kidney [nTPM]":"12.4","Tissue RNA - liver [nTPM]":"11.5","Tissue RNA - lung [nTPM]":"25.7","Tissue RNA - lymph node [nTPM]":"7.9","Tissue RNA - medulla oblongata [nTPM]":"1.6","Tissue RNA - midbrain [nTPM]":"1.1","Tissue RNA - ovary [nTPM]":"9.2","Tissue RNA - pancreas [nTPM]":"9.0","Tissue RNA - parathyroid gland [nTPM]":"3.7","Tissue RNA - pituitary gland [nTPM]":"8.2","Tissue RNA - placenta [nTPM]":"3.1","Tissue RNA - pons [nTPM]":"1.5","Tissue RNA - prostate [nTPM]":"9.9","Tissue RNA - rectum [nTPM]":"5.5","Tissue RNA - retina [nTPM]":"2.5","Tissue RNA - salivary gland [nTPM]":"11.2","Tissue RNA - seminal vesicle [nTPM]":"2.1","Tissue RNA - skeletal muscle [nTPM]":"8.6","Tissue RNA - skin 1 [nTPM]":"14.5","Tissue RNA - small intestine [nTPM]":"25.2","Tissue RNA - smooth muscle [nTPM]":"4.1","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"29.8","Tissue RNA - stomach 1 [nTPM]":"11.4","Tissue RNA - testis [nTPM]":"2.5","Tissue RNA - thalamus [nTPM]":"1.8","Tissue RNA - thymus [nTPM]":"9.7","Tissue RNA - thyroid gland [nTPM]":"12.3","Tissue RNA - tongue [nTPM]":"5.8","Tissue RNA - tonsil [nTPM]":"8.1","Tissue RNA - urinary bladder [nTPM]":"10.6","Tissue RNA - vagina [nTPM]":"17.2","Tissue RNA - white matter [nTPM]":"1.7","Cell RNA - A-431 [nTPM]":"4.4","Cell RNA - A549 [nTPM]":"2.0","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"5.0","Cell RNA - ASC diff [nTPM]":"6.1","Cell RNA - ASC TERT1 [nTPM]":"6.5","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"2.3","Cell RNA - BJ hTERT+ [nTPM]":"3.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.7","Cell RNA - CACO-2 [nTPM]":"3.9","Cell RNA - CAPAN-2 [nTPM]":"41.0","Cell RNA - Daudi [nTPM]":"36.5","Cell RNA - EFO-21 [nTPM]":"7.5","Cell RNA - fHDF\/TERT166 [nTPM]":"9.1","Cell RNA - GAMG [nTPM]":"37.1","Cell RNA - HaCaT [nTPM]":"38.8","Cell RNA - HAP1 [nTPM]":"15.8","Cell RNA - HBEC3-KT [nTPM]":"61.4","Cell RNA - HBF TERT88 [nTPM]":"6.9","Cell RNA - HDLM-2 [nTPM]":"43.8","Cell RNA - HEK 293 [nTPM]":"1.9","Cell RNA - HEL [nTPM]":"20.3","Cell RNA - HeLa [nTPM]":"11.6","Cell RNA - Hep G2 [nTPM]":"1.3","Cell RNA - HHSteC [nTPM]":"8.5","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"29.5","Cell RNA - HSkMC [nTPM]":"0.6","Cell RNA - hTCEpi [nTPM]":"2.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.3","Cell RNA - hTERT-HME1 [nTPM]":"24.8","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"12.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"20.0","Cell RNA - Karpas-707 [nTPM]":"12.2","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"1.6","Cell RNA - MOLT-4 [nTPM]":"5.8","Cell RNA - NB-4 [nTPM]":"2.4","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"11.7","Cell RNA - REH [nTPM]":"25.8","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"12.8","Cell RNA - RPTEC TERT1 [nTPM]":"10.9","Cell RNA - RT4 [nTPM]":"1.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"16.0","Cell RNA - SK-BR-3 [nTPM]":"37.3","Cell RNA - SK-MEL-30 [nTPM]":"4.1","Cell RNA - SuSa [nTPM]":"1.0","Cell RNA - T-47d [nTPM]":"7.4","Cell RNA - THP-1 [nTPM]":"1.9","Cell RNA - TIME [nTPM]":"5.7","Cell RNA - U-138 MG [nTPM]":"25.7","Cell RNA - U-2 OS [nTPM]":"6.9","Cell RNA - U-2197 [nTPM]":"3.9","Cell RNA - U-251 MG [nTPM]":"52.0","Cell RNA - U-266\/70 [nTPM]":"17.9","Cell RNA - U-266\/84 [nTPM]":"31.4","Cell RNA - U-698 [nTPM]":"33.3","Cell RNA - U-87 MG [nTPM]":"19.5","Cell RNA - U-937 [nTPM]":"25.7","Cell RNA - WM-115 [nTPM]":"10.9","Blood RNA - basophil [nTPM]":"1.8","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"1.6","Blood RNA - gdT-cell [nTPM]":"3.0","Blood RNA - intermediate monocyte [nTPM]":"3.2","Blood RNA - MAIT T-cell [nTPM]":"1.7","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"0.8","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"3.8","Blood RNA - NK-cell [nTPM]":"1.9","Blood RNA - non-classical monocyte [nTPM]":"2.8","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"1.0","Brain RNA - basal ganglia [nTPM]":"1.0","Brain RNA - cerebellum [nTPM]":"0.8","Brain RNA - cerebral cortex [nTPM]":"1.2","Brain RNA - hippocampal formation [nTPM]":"1.2","Brain RNA - hypothalamus [nTPM]":"2.0","Brain RNA - medulla oblongata [nTPM]":"1.6","Brain RNA - midbrain [nTPM]":"1.1","Brain RNA - pons [nTPM]":"1.5","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"1.8","Brain RNA - white matter [nTPM]":"1.7","Single Cell Type RNA - Adipocytes [nTPM]":"48.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.5","Single Cell Type RNA - Astrocytes [nTPM]":"7.5","Single Cell Type RNA - B-cells [nTPM]":"20.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"5.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"3.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - dendritic cells [nTPM]":"37.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"21.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"34.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.4","Single Cell Type RNA - Endothelial cells [nTPM]":"32.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"4.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"33.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"45.8","Single Cell Type RNA - Fibroblasts [nTPM]":"8.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"41.9","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"8.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.4","Single Cell Type RNA - Hepatocytes [nTPM]":"8.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.9","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"18.9","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"5.6","Single Cell Type RNA - Macrophages [nTPM]":"20.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"69.3","Single Cell Type RNA - Muller glia cells [nTPM]":"17.7","Single Cell Type RNA - NK-cells [nTPM]":"47.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"35.1","Single Cell Type RNA - Paneth cells [nTPM]":"12.6","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"18.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"29.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"55.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"2.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.6","Single Cell Type RNA - T-cells [nTPM]":"24.0","Single Cell Type RNA - Theca cells [nTPM]":"20.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.3","Single Cell Type RNA - Urothelial cells [nTPM]":"16.7"},{"Gene":"TAPBP","Gene synonym":["TAPA"],"Ensembl":"ENSG00000231925","Gene description":"TAP binding protein","Uniprot":["O15533"],"Chromosome":"6","Position":"33299694-33314387","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"168.7","Karpas-707":"140.8","U-266\/70":"140.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007066"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"20000","Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 1: Pancreatic cells - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA007066":"AB_1857769"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.76e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.29e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-3"},"Tissue RNA - adipose tissue [nTPM]":"47.3","Tissue RNA - adrenal gland [nTPM]":"73.1","Tissue RNA - amygdala [nTPM]":"2.4","Tissue RNA - appendix [nTPM]":"28.5","Tissue RNA - basal ganglia [nTPM]":"4.8","Tissue RNA - bone marrow [nTPM]":"25.0","Tissue RNA - breast [nTPM]":"43.1","Tissue RNA - cerebellum [nTPM]":"1.9","Tissue RNA - cerebral cortex [nTPM]":"2.8","Tissue RNA - cervix [nTPM]":"40.1","Tissue RNA - choroid plexus [nTPM]":"1.2","Tissue RNA - colon [nTPM]":"66.7","Tissue RNA - duodenum [nTPM]":"52.3","Tissue RNA - endometrium 1 [nTPM]":"38.2","Tissue RNA - epididymis [nTPM]":"13.3","Tissue RNA - esophagus [nTPM]":"57.3","Tissue RNA - fallopian tube [nTPM]":"43.8","Tissue RNA - gallbladder [nTPM]":"10.5","Tissue RNA - heart muscle [nTPM]":"63.7","Tissue RNA - hippocampal formation [nTPM]":"2.9","Tissue RNA - hypothalamus [nTPM]":"1.8","Tissue RNA - kidney [nTPM]":"67.4","Tissue RNA - liver [nTPM]":"107.5","Tissue RNA - lung [nTPM]":"82.1","Tissue RNA - lymph node [nTPM]":"21.2","Tissue RNA - medulla oblongata [nTPM]":"2.7","Tissue RNA - midbrain [nTPM]":"3.2","Tissue RNA - ovary [nTPM]":"33.3","Tissue RNA - pancreas [nTPM]":"48.2","Tissue RNA - parathyroid gland [nTPM]":"14.9","Tissue RNA - pituitary gland [nTPM]":"38.8","Tissue RNA - placenta [nTPM]":"18.7","Tissue RNA - pons [nTPM]":"2.0","Tissue RNA - prostate [nTPM]":"64.3","Tissue RNA - rectum [nTPM]":"19.6","Tissue RNA - retina [nTPM]":"4.1","Tissue RNA - salivary gland [nTPM]":"61.9","Tissue RNA - seminal vesicle [nTPM]":"17.2","Tissue RNA - skeletal muscle [nTPM]":"26.7","Tissue RNA - skin 1 [nTPM]":"54.0","Tissue RNA - small intestine [nTPM]":"81.9","Tissue RNA - smooth muscle [nTPM]":"23.1","Tissue RNA - spinal cord [nTPM]":"1.9","Tissue RNA - spleen [nTPM]":"129.0","Tissue RNA - stomach 1 [nTPM]":"52.1","Tissue RNA - testis [nTPM]":"16.2","Tissue RNA - thalamus [nTPM]":"2.0","Tissue RNA - thymus [nTPM]":"24.4","Tissue RNA - thyroid gland [nTPM]":"59.1","Tissue RNA - tongue [nTPM]":"6.5","Tissue RNA - tonsil [nTPM]":"36.7","Tissue RNA - urinary bladder [nTPM]":"45.0","Tissue RNA - vagina [nTPM]":"43.4","Tissue RNA - white matter [nTPM]":"2.4","Cell RNA - A-431 [nTPM]":"3.3","Cell RNA - A549 [nTPM]":"1.2","Cell RNA - AF22 [nTPM]":"6.3","Cell RNA - AN3-CA [nTPM]":"26.1","Cell RNA - ASC diff [nTPM]":"20.3","Cell RNA - ASC TERT1 [nTPM]":"25.6","Cell RNA - BEWO [nTPM]":"92.9","Cell RNA - BJ [nTPM]":"18.5","Cell RNA - BJ hTERT+ [nTPM]":"88.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"42.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"57.1","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"168.7","Cell RNA - Daudi [nTPM]":"48.1","Cell RNA - EFO-21 [nTPM]":"38.1","Cell RNA - fHDF\/TERT166 [nTPM]":"41.3","Cell RNA - GAMG [nTPM]":"92.2","Cell RNA - HaCaT [nTPM]":"2.9","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"30.3","Cell RNA - HBF TERT88 [nTPM]":"15.8","Cell RNA - HDLM-2 [nTPM]":"125.5","Cell RNA - HEK 293 [nTPM]":"4.1","Cell RNA - HEL [nTPM]":"19.1","Cell RNA - HeLa [nTPM]":"9.9","Cell RNA - Hep G2 [nTPM]":"24.8","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"20.4","Cell RNA - HMC-1 [nTPM]":"63.0","Cell RNA - HSkMC [nTPM]":"51.7","Cell RNA - hTCEpi [nTPM]":"20.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.8","Cell RNA - hTERT-HME1 [nTPM]":"8.2","Cell RNA - hTERT-RPE1 [nTPM]":"37.8","Cell RNA - HUVEC TERT2 [nTPM]":"0.4","Cell RNA - JURKAT [nTPM]":"16.0","Cell RNA - K-562 [nTPM]":"1.5","Cell RNA - Karpas-707 [nTPM]":"140.8","Cell RNA - LHCN-M2 [nTPM]":"14.7","Cell RNA - MCF7 [nTPM]":"19.6","Cell RNA - MOLT-4 [nTPM]":"51.9","Cell RNA - NB-4 [nTPM]":"44.1","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"6.3","Cell RNA - REH [nTPM]":"2.8","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"1.3","Cell RNA - RPTEC TERT1 [nTPM]":"35.5","Cell RNA - RT4 [nTPM]":"1.2","Cell RNA - SCLC-21H [nTPM]":"8.6","Cell RNA - SH-SY5Y [nTPM]":"0.6","Cell RNA - SiHa [nTPM]":"0.6","Cell RNA - SK-BR-3 [nTPM]":"2.4","Cell RNA - SK-MEL-30 [nTPM]":"23.7","Cell RNA - SuSa [nTPM]":"3.7","Cell RNA - T-47d [nTPM]":"1.4","Cell RNA - THP-1 [nTPM]":"0.9","Cell RNA - TIME [nTPM]":"45.5","Cell RNA - U-138 MG [nTPM]":"89.4","Cell RNA - U-2 OS [nTPM]":"18.6","Cell RNA - U-2197 [nTPM]":"1.3","Cell RNA - U-251 MG [nTPM]":"2.0","Cell RNA - U-266\/70 [nTPM]":"140.5","Cell RNA - U-266\/84 [nTPM]":"117.4","Cell RNA - U-698 [nTPM]":"46.2","Cell RNA - U-87 MG [nTPM]":"58.6","Cell RNA - U-937 [nTPM]":"38.8","Cell RNA - WM-115 [nTPM]":"58.8","Blood RNA - basophil [nTPM]":"159.7","Blood RNA - classical monocyte [nTPM]":"87.9","Blood RNA - eosinophil [nTPM]":"172.1","Blood RNA - gdT-cell [nTPM]":"137.3","Blood RNA - intermediate monocyte [nTPM]":"121.6","Blood RNA - MAIT T-cell [nTPM]":"117.0","Blood RNA - memory B-cell [nTPM]":"97.1","Blood RNA - memory CD4 T-cell [nTPM]":"99.7","Blood RNA - memory CD8 T-cell [nTPM]":"114.3","Blood RNA - myeloid DC [nTPM]":"90.0","Blood RNA - naive B-cell [nTPM]":"86.0","Blood RNA - naive CD4 T-cell [nTPM]":"76.2","Blood RNA - naive CD8 T-cell [nTPM]":"109.9","Blood RNA - neutrophil [nTPM]":"151.3","Blood RNA - NK-cell [nTPM]":"159.6","Blood RNA - non-classical monocyte [nTPM]":"139.0","Blood RNA - plasmacytoid DC [nTPM]":"102.9","Blood RNA - T-reg [nTPM]":"85.9","Blood RNA - total PBMC [nTPM]":"150.5","Brain RNA - amygdala [nTPM]":"2.4","Brain RNA - basal ganglia [nTPM]":"4.8","Brain RNA - cerebellum [nTPM]":"1.9","Brain RNA - cerebral cortex [nTPM]":"2.8","Brain RNA - hippocampal formation [nTPM]":"2.9","Brain RNA - hypothalamus [nTPM]":"1.8","Brain RNA - medulla oblongata [nTPM]":"2.7","Brain RNA - midbrain [nTPM]":"3.2","Brain RNA - pons [nTPM]":"2.0","Brain RNA - spinal cord [nTPM]":"1.9","Brain RNA - thalamus [nTPM]":"2.0","Brain RNA - white matter [nTPM]":"2.4","Single Cell Type RNA - Adipocytes [nTPM]":"116.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"125.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"102.1","Single Cell Type RNA - Astrocytes [nTPM]":"22.5","Single Cell Type RNA - B-cells [nTPM]":"186.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"77.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"93.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"148.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"66.6","Single Cell Type RNA - Bipolar cells [nTPM]":"34.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"82.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"64.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"73.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"84.4","Single Cell Type RNA - Club cells [nTPM]":"105.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"71.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"46.9","Single Cell Type RNA - dendritic cells [nTPM]":"223.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"259.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"256.4","Single Cell Type RNA - Early spermatids [nTPM]":"1.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"64.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"52.4","Single Cell Type RNA - Endothelial cells [nTPM]":"99.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"84.6","Single Cell Type RNA - Erythroid cells [nTPM]":"58.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"282.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"85.9","Single Cell Type RNA - Fibroblasts [nTPM]":"63.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"105.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"78.4","Single Cell Type RNA - granulocytes [nTPM]":"91.9","Single Cell Type RNA - Granulosa cells [nTPM]":"65.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"75.0","Single Cell Type RNA - Hepatocytes [nTPM]":"143.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"119.7","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"174.6","Single Cell Type RNA - Ionocytes [nTPM]":"83.4","Single Cell Type RNA - Kupffer cells [nTPM]":"124.3","Single Cell Type RNA - Langerhans cells [nTPM]":"128.0","Single Cell Type RNA - Late spermatids [nTPM]":"9.2","Single Cell Type RNA - Leydig cells [nTPM]":"33.2","Single Cell Type RNA - Macrophages [nTPM]":"131.9","Single Cell Type RNA - Melanocytes [nTPM]":"119.2","Single Cell Type RNA - Microglial cells [nTPM]":"30.9","Single Cell Type RNA - monocytes [nTPM]":"229.3","Single Cell Type RNA - Muller glia cells [nTPM]":"34.7","Single Cell Type RNA - NK-cells [nTPM]":"195.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"23.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"215.5","Single Cell Type RNA - Paneth cells [nTPM]":"172.4","Single Cell Type RNA - Peritubular cells [nTPM]":"32.0","Single Cell Type RNA - Plasma cells [nTPM]":"194.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"130.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"283.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"33.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"113.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"30.4","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"39.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"57.6","Single Cell Type RNA - Spermatocytes [nTPM]":"1.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"53.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"56.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"49.1","Single Cell Type RNA - T-cells [nTPM]":"163.7","Single Cell Type RNA - Theca cells [nTPM]":"66.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"162.3","Single Cell Type RNA - Urothelial cells [nTPM]":"141.0"},{"Gene":"TARS1","Gene synonym":["TARS"],"Ensembl":"ENSG00000113407","Gene description":"Threonyl-tRNA synthetase 1","Uniprot":["P26639"],"Chromosome":"5","Position":"33440696-33468091","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase","RNA-binding","tRNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"63.4","Cytotrophoblasts":"36.6","dendritic cells":"15.9","Extravillous trophoblasts":"42.1","Hofbauer cells":"32.1","Syncytiotrophoblasts":"52.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037425"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"580000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":["Actin filaments"],"Antibody RRID":{"HPA037425":"AB_10672279"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.14e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.17e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.88e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.63e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"},"Tissue RNA - adipose tissue [nTPM]":"29.0","Tissue RNA - adrenal gland [nTPM]":"32.2","Tissue RNA - amygdala [nTPM]":"13.7","Tissue RNA - appendix [nTPM]":"33.8","Tissue RNA - basal ganglia [nTPM]":"16.2","Tissue RNA - bone marrow [nTPM]":"45.0","Tissue RNA - breast [nTPM]":"26.8","Tissue RNA - cerebellum [nTPM]":"20.0","Tissue RNA - cerebral cortex [nTPM]":"20.1","Tissue RNA - cervix [nTPM]":"24.0","Tissue RNA - choroid plexus [nTPM]":"17.1","Tissue RNA - colon [nTPM]":"42.6","Tissue RNA - duodenum [nTPM]":"30.7","Tissue RNA - endometrium 1 [nTPM]":"24.7","Tissue RNA - epididymis [nTPM]":"35.8","Tissue RNA - esophagus [nTPM]":"40.9","Tissue RNA - fallopian tube [nTPM]":"17.4","Tissue RNA - gallbladder [nTPM]":"19.9","Tissue RNA - heart muscle [nTPM]":"38.7","Tissue RNA - hippocampal formation [nTPM]":"13.8","Tissue RNA - hypothalamus [nTPM]":"17.9","Tissue RNA - kidney [nTPM]":"32.4","Tissue RNA - liver [nTPM]":"68.6","Tissue RNA - lung [nTPM]":"24.1","Tissue RNA - lymph node [nTPM]":"29.9","Tissue RNA - medulla oblongata [nTPM]":"22.4","Tissue RNA - midbrain [nTPM]":"18.5","Tissue RNA - ovary [nTPM]":"17.9","Tissue RNA - pancreas [nTPM]":"68.1","Tissue RNA - parathyroid gland [nTPM]":"33.8","Tissue RNA - pituitary gland [nTPM]":"9.9","Tissue RNA - placenta [nTPM]":"37.1","Tissue RNA - pons [nTPM]":"18.3","Tissue RNA - prostate [nTPM]":"27.6","Tissue RNA - rectum [nTPM]":"42.8","Tissue RNA - retina [nTPM]":"40.7","Tissue RNA - salivary gland [nTPM]":"36.8","Tissue RNA - seminal vesicle [nTPM]":"26.4","Tissue RNA - skeletal muscle [nTPM]":"38.4","Tissue RNA - skin 1 [nTPM]":"19.1","Tissue RNA - small intestine [nTPM]":"29.8","Tissue RNA - smooth muscle [nTPM]":"37.2","Tissue RNA - spinal cord [nTPM]":"18.4","Tissue RNA - spleen [nTPM]":"21.7","Tissue RNA - stomach 1 [nTPM]":"40.0","Tissue RNA - testis [nTPM]":"18.7","Tissue RNA - thalamus [nTPM]":"18.3","Tissue RNA - thymus [nTPM]":"31.7","Tissue RNA - thyroid gland [nTPM]":"37.6","Tissue RNA - tongue [nTPM]":"28.4","Tissue RNA - tonsil [nTPM]":"40.1","Tissue RNA - urinary bladder [nTPM]":"42.9","Tissue RNA - vagina [nTPM]":"10.8","Tissue RNA - white matter [nTPM]":"22.6","Cell RNA - A-431 [nTPM]":"253.0","Cell RNA - A549 [nTPM]":"136.1","Cell RNA - AF22 [nTPM]":"132.7","Cell RNA - AN3-CA [nTPM]":"189.5","Cell RNA - ASC diff [nTPM]":"80.2","Cell RNA - ASC TERT1 [nTPM]":"129.9","Cell RNA - BEWO [nTPM]":"230.1","Cell RNA - BJ [nTPM]":"237.5","Cell RNA - BJ hTERT+ [nTPM]":"172.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"152.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"163.7","Cell RNA - CACO-2 [nTPM]":"176.6","Cell RNA - CAPAN-2 [nTPM]":"128.7","Cell RNA - Daudi [nTPM]":"96.0","Cell RNA - EFO-21 [nTPM]":"84.8","Cell RNA - fHDF\/TERT166 [nTPM]":"176.5","Cell RNA - GAMG [nTPM]":"271.8","Cell RNA - HaCaT [nTPM]":"151.1","Cell RNA - HAP1 [nTPM]":"261.1","Cell RNA - HBEC3-KT [nTPM]":"207.1","Cell RNA - HBF TERT88 [nTPM]":"267.4","Cell RNA - HDLM-2 [nTPM]":"158.9","Cell RNA - HEK 293 [nTPM]":"140.5","Cell RNA - HEL [nTPM]":"151.1","Cell RNA - HeLa [nTPM]":"332.9","Cell RNA - Hep G2 [nTPM]":"108.5","Cell RNA - HHSteC [nTPM]":"256.7","Cell RNA - HL-60 [nTPM]":"225.6","Cell RNA - HMC-1 [nTPM]":"141.0","Cell RNA - HSkMC [nTPM]":"133.7","Cell RNA - hTCEpi [nTPM]":"287.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"217.5","Cell RNA - hTERT-HME1 [nTPM]":"273.9","Cell RNA - hTERT-RPE1 [nTPM]":"102.4","Cell RNA - HUVEC TERT2 [nTPM]":"144.3","Cell RNA - JURKAT [nTPM]":"191.8","Cell RNA - K-562 [nTPM]":"236.3","Cell RNA - Karpas-707 [nTPM]":"204.6","Cell RNA - LHCN-M2 [nTPM]":"191.5","Cell RNA - MCF7 [nTPM]":"105.7","Cell RNA - MOLT-4 [nTPM]":"166.3","Cell RNA - NB-4 [nTPM]":"104.7","Cell RNA - NTERA-2 [nTPM]":"159.2","Cell RNA - OE19 [nTPM]":"181.5","Cell RNA - PC-3 [nTPM]":"168.4","Cell RNA - REH [nTPM]":"137.1","Cell RNA - RH-30 [nTPM]":"237.9","Cell RNA - RPMI-8226 [nTPM]":"123.4","Cell RNA - RPTEC TERT1 [nTPM]":"170.8","Cell RNA - RT4 [nTPM]":"119.8","Cell RNA - SCLC-21H [nTPM]":"81.0","Cell RNA - SH-SY5Y [nTPM]":"102.7","Cell RNA - SiHa [nTPM]":"245.6","Cell RNA - SK-BR-3 [nTPM]":"175.8","Cell RNA - SK-MEL-30 [nTPM]":"195.5","Cell RNA - SuSa [nTPM]":"103.8","Cell RNA - T-47d [nTPM]":"85.9","Cell RNA - THP-1 [nTPM]":"236.3","Cell RNA - TIME [nTPM]":"123.0","Cell RNA - U-138 MG [nTPM]":"132.8","Cell RNA - U-2 OS [nTPM]":"211.9","Cell RNA - U-2197 [nTPM]":"102.5","Cell RNA - U-251 MG [nTPM]":"196.3","Cell RNA - U-266\/70 [nTPM]":"135.4","Cell RNA - U-266\/84 [nTPM]":"258.4","Cell RNA - U-698 [nTPM]":"132.6","Cell RNA - U-87 MG [nTPM]":"156.2","Cell RNA - U-937 [nTPM]":"302.6","Cell RNA - WM-115 [nTPM]":"148.3","Blood RNA - basophil [nTPM]":"34.2","Blood RNA - classical monocyte [nTPM]":"22.0","Blood RNA - eosinophil [nTPM]":"22.6","Blood RNA - gdT-cell [nTPM]":"27.4","Blood RNA - intermediate monocyte [nTPM]":"24.5","Blood RNA - MAIT T-cell [nTPM]":"27.6","Blood RNA - memory B-cell [nTPM]":"28.7","Blood RNA - memory CD4 T-cell [nTPM]":"25.2","Blood RNA - memory CD8 T-cell [nTPM]":"26.6","Blood RNA - myeloid DC [nTPM]":"32.6","Blood RNA - naive B-cell [nTPM]":"23.9","Blood RNA - naive CD4 T-cell [nTPM]":"21.5","Blood RNA - naive CD8 T-cell [nTPM]":"27.5","Blood RNA - neutrophil [nTPM]":"2.6","Blood RNA - NK-cell [nTPM]":"46.2","Blood RNA - non-classical monocyte [nTPM]":"18.3","Blood RNA - plasmacytoid DC [nTPM]":"18.3","Blood RNA - T-reg [nTPM]":"24.2","Blood RNA - total PBMC [nTPM]":"20.6","Brain RNA - amygdala [nTPM]":"13.7","Brain RNA - basal ganglia [nTPM]":"16.2","Brain RNA - cerebellum [nTPM]":"20.0","Brain RNA - cerebral cortex [nTPM]":"20.1","Brain RNA - hippocampal formation [nTPM]":"13.8","Brain RNA - hypothalamus [nTPM]":"17.9","Brain RNA - medulla oblongata [nTPM]":"22.4","Brain RNA - midbrain [nTPM]":"18.5","Brain RNA - pons [nTPM]":"18.3","Brain RNA - spinal cord [nTPM]":"18.4","Brain RNA - thalamus [nTPM]":"18.3","Brain RNA - white matter [nTPM]":"22.6","Single Cell Type RNA - Adipocytes [nTPM]":"12.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"63.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"36.6","Single Cell Type RNA - dendritic cells [nTPM]":"15.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"3.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"42.1","Single Cell Type RNA - Fibroblasts [nTPM]":"11.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"32.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"2.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"6.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"52.1","Single Cell Type RNA - T-cells [nTPM]":"2.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"TARS2","Gene synonym":["FLJ12528","TARSL1"],"Ensembl":"ENSG00000143374","Gene description":"Threonyl-tRNA synthetase 2, mitochondrial","Uniprot":["Q9BW92"],"Chromosome":"1","Position":"150487364-150507609","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028626"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA028626":"AB_10601719"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.8","Tissue RNA - adrenal gland [nTPM]":"16.5","Tissue RNA - amygdala [nTPM]":"11.8","Tissue RNA - appendix [nTPM]":"10.6","Tissue RNA - basal ganglia [nTPM]":"11.4","Tissue RNA - bone marrow [nTPM]":"10.0","Tissue RNA - breast [nTPM]":"10.3","Tissue RNA - cerebellum [nTPM]":"11.2","Tissue RNA - cerebral cortex [nTPM]":"12.5","Tissue RNA - cervix [nTPM]":"9.5","Tissue RNA - choroid plexus [nTPM]":"10.9","Tissue RNA - colon [nTPM]":"10.3","Tissue RNA - duodenum [nTPM]":"8.9","Tissue RNA - endometrium 1 [nTPM]":"8.9","Tissue RNA - epididymis [nTPM]":"13.0","Tissue RNA - esophagus [nTPM]":"13.4","Tissue RNA - fallopian tube [nTPM]":"11.7","Tissue RNA - gallbladder [nTPM]":"7.7","Tissue RNA - heart muscle [nTPM]":"20.3","Tissue RNA - hippocampal formation [nTPM]":"11.3","Tissue RNA - hypothalamus [nTPM]":"11.5","Tissue RNA - kidney [nTPM]":"14.3","Tissue RNA - liver [nTPM]":"25.3","Tissue RNA - lung [nTPM]":"8.6","Tissue RNA - lymph node [nTPM]":"14.7","Tissue RNA - medulla oblongata [nTPM]":"12.0","Tissue RNA - midbrain [nTPM]":"11.5","Tissue RNA - ovary [nTPM]":"11.7","Tissue RNA - pancreas [nTPM]":"8.4","Tissue RNA - parathyroid gland [nTPM]":"17.7","Tissue RNA - pituitary gland [nTPM]":"9.3","Tissue RNA - placenta [nTPM]":"8.9","Tissue RNA - pons [nTPM]":"12.7","Tissue RNA - prostate [nTPM]":"8.7","Tissue RNA - rectum [nTPM]":"11.3","Tissue RNA - retina [nTPM]":"14.7","Tissue RNA - salivary gland [nTPM]":"9.7","Tissue RNA - seminal vesicle [nTPM]":"9.3","Tissue RNA - skeletal muscle [nTPM]":"31.9","Tissue RNA - skin 1 [nTPM]":"11.8","Tissue RNA - small intestine [nTPM]":"9.6","Tissue RNA - smooth muscle [nTPM]":"10.0","Tissue RNA - spinal cord [nTPM]":"10.4","Tissue RNA - spleen [nTPM]":"12.5","Tissue RNA - stomach 1 [nTPM]":"12.0","Tissue RNA - testis [nTPM]":"11.0","Tissue RNA - thalamus [nTPM]":"11.9","Tissue RNA - thymus [nTPM]":"12.6","Tissue RNA - thyroid gland [nTPM]":"11.2","Tissue RNA - tongue [nTPM]":"31.1","Tissue RNA - tonsil [nTPM]":"15.4","Tissue RNA - urinary bladder [nTPM]":"9.6","Tissue RNA - vagina [nTPM]":"9.4","Tissue RNA - white matter [nTPM]":"12.8","Cell RNA - A-431 [nTPM]":"33.5","Cell RNA - A549 [nTPM]":"27.4","Cell RNA - AF22 [nTPM]":"18.1","Cell RNA - AN3-CA [nTPM]":"27.4","Cell RNA - ASC diff [nTPM]":"19.9","Cell RNA - ASC TERT1 [nTPM]":"18.2","Cell RNA - BEWO [nTPM]":"34.1","Cell RNA - BJ [nTPM]":"15.9","Cell RNA - BJ hTERT+ [nTPM]":"17.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"30.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"30.8","Cell RNA - CACO-2 [nTPM]":"22.4","Cell RNA - CAPAN-2 [nTPM]":"30.3","Cell RNA - Daudi [nTPM]":"48.0","Cell RNA - EFO-21 [nTPM]":"34.2","Cell RNA - fHDF\/TERT166 [nTPM]":"12.0","Cell RNA - GAMG [nTPM]":"21.1","Cell RNA - HaCaT [nTPM]":"33.8","Cell RNA - HAP1 [nTPM]":"44.2","Cell RNA - HBEC3-KT [nTPM]":"36.8","Cell RNA - HBF TERT88 [nTPM]":"23.5","Cell RNA - HDLM-2 [nTPM]":"29.2","Cell RNA - HEK 293 [nTPM]":"38.4","Cell RNA - HEL [nTPM]":"22.7","Cell RNA - HeLa [nTPM]":"25.2","Cell RNA - Hep G2 [nTPM]":"22.7","Cell RNA - HHSteC [nTPM]":"19.7","Cell RNA - HL-60 [nTPM]":"31.4","Cell RNA - HMC-1 [nTPM]":"33.4","Cell RNA - HSkMC [nTPM]":"16.2","Cell RNA - hTCEpi [nTPM]":"30.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"23.4","Cell RNA - hTERT-HME1 [nTPM]":"31.6","Cell RNA - hTERT-RPE1 [nTPM]":"19.9","Cell RNA - HUVEC TERT2 [nTPM]":"20.1","Cell RNA - JURKAT [nTPM]":"26.4","Cell RNA - K-562 [nTPM]":"40.3","Cell RNA - Karpas-707 [nTPM]":"32.6","Cell RNA - LHCN-M2 [nTPM]":"21.8","Cell RNA - MCF7 [nTPM]":"40.4","Cell RNA - MOLT-4 [nTPM]":"27.0","Cell RNA - NB-4 [nTPM]":"26.0","Cell RNA - NTERA-2 [nTPM]":"22.3","Cell RNA - OE19 [nTPM]":"46.0","Cell RNA - PC-3 [nTPM]":"40.2","Cell RNA - REH [nTPM]":"27.5","Cell RNA - RH-30 [nTPM]":"23.0","Cell RNA - RPMI-8226 [nTPM]":"59.8","Cell RNA - RPTEC TERT1 [nTPM]":"20.9","Cell RNA - RT4 [nTPM]":"15.7","Cell RNA - SCLC-21H [nTPM]":"25.5","Cell RNA - SH-SY5Y [nTPM]":"29.8","Cell RNA - SiHa [nTPM]":"24.1","Cell RNA - SK-BR-3 [nTPM]":"52.5","Cell RNA - SK-MEL-30 [nTPM]":"38.7","Cell RNA - SuSa [nTPM]":"25.4","Cell RNA - T-47d [nTPM]":"42.3","Cell RNA - THP-1 [nTPM]":"48.9","Cell RNA - TIME [nTPM]":"11.9","Cell RNA - U-138 MG [nTPM]":"17.8","Cell RNA - U-2 OS [nTPM]":"18.8","Cell RNA - U-2197 [nTPM]":"14.9","Cell RNA - U-251 MG [nTPM]":"27.2","Cell RNA - U-266\/70 [nTPM]":"31.2","Cell RNA - U-266\/84 [nTPM]":"39.6","Cell RNA - U-698 [nTPM]":"36.2","Cell RNA - U-87 MG [nTPM]":"26.6","Cell RNA - U-937 [nTPM]":"36.3","Cell RNA - WM-115 [nTPM]":"17.6","Blood RNA - basophil [nTPM]":"30.5","Blood RNA - classical monocyte [nTPM]":"15.4","Blood RNA - eosinophil [nTPM]":"30.5","Blood RNA - gdT-cell [nTPM]":"21.0","Blood RNA - intermediate monocyte [nTPM]":"27.0","Blood RNA - MAIT T-cell [nTPM]":"21.3","Blood RNA - memory B-cell [nTPM]":"28.7","Blood RNA - memory CD4 T-cell [nTPM]":"20.5","Blood RNA - memory CD8 T-cell [nTPM]":"21.2","Blood RNA - myeloid DC [nTPM]":"25.0","Blood RNA - naive B-cell [nTPM]":"25.3","Blood RNA - naive CD4 T-cell [nTPM]":"19.6","Blood RNA - naive CD8 T-cell [nTPM]":"20.7","Blood RNA - neutrophil [nTPM]":"2.4","Blood RNA - NK-cell [nTPM]":"33.2","Blood RNA - non-classical monocyte [nTPM]":"29.3","Blood RNA - plasmacytoid DC [nTPM]":"16.7","Blood RNA - T-reg [nTPM]":"31.4","Blood RNA - total PBMC [nTPM]":"18.3","Brain RNA - amygdala [nTPM]":"11.8","Brain RNA - basal ganglia [nTPM]":"11.4","Brain RNA - cerebellum [nTPM]":"11.2","Brain RNA - cerebral cortex [nTPM]":"12.5","Brain RNA - hippocampal formation [nTPM]":"11.3","Brain RNA - hypothalamus [nTPM]":"11.5","Brain RNA - medulla oblongata [nTPM]":"12.0","Brain RNA - midbrain [nTPM]":"11.5","Brain RNA - pons [nTPM]":"12.7","Brain RNA - spinal cord [nTPM]":"10.4","Brain RNA - thalamus [nTPM]":"11.9","Brain RNA - white matter [nTPM]":"12.8","Single Cell Type RNA - Adipocytes [nTPM]":"6.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.8","Single Cell Type RNA - Astrocytes [nTPM]":"6.2","Single Cell Type RNA - B-cells [nTPM]":"13.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"15.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"22.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"11.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"24.5","Single Cell Type RNA - dendritic cells [nTPM]":"8.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"11.5","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.8","Single Cell Type RNA - Endothelial cells [nTPM]":"7.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"11.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.3","Single Cell Type RNA - Fibroblasts [nTPM]":"8.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.7","Single Cell Type RNA - granulocytes [nTPM]":"22.2","Single Cell Type RNA - Granulosa cells [nTPM]":"11.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"22.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.2","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.6","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"7.7","Single Cell Type RNA - Langerhans cells [nTPM]":"5.2","Single Cell Type RNA - Late spermatids [nTPM]":"2.5","Single Cell Type RNA - Leydig cells [nTPM]":"8.4","Single Cell Type RNA - Macrophages [nTPM]":"8.8","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"12.5","Single Cell Type RNA - Muller glia cells [nTPM]":"7.6","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.9","Single Cell Type RNA - Paneth cells [nTPM]":"3.5","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"9.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.3","Single Cell Type RNA - Spermatocytes [nTPM]":"18.2","Single Cell Type RNA - Spermatogonia [nTPM]":"12.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.1","Single Cell Type RNA - T-cells [nTPM]":"10.6","Single Cell Type RNA - Theca cells [nTPM]":"15.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.6","Single Cell Type RNA - Urothelial cells [nTPM]":"4.8"},{"Gene":"TAT","Gene synonym":[],"Ensembl":"ENSG00000198650","Gene description":"Tyrosine aminotransferase","Uniprot":["P17735"],"Chromosome":"16","Position":"71565660-71577092","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Phenylalanine catabolism","Tyrosine catabolism"],"Molecular function":["Aminotransferase","Transferase"],"Disease involvement":["Disease variant","Mental retardation","Palmoplantar keratoderma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"22","RNA tissue specific nTPM":{"liver":"1272.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"43","RNA single cell type specific nTPM":{"Hepatocytes":"4164.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"10","RNA cancer specific FPKM":{"liver cancer":"152.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"2.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.51e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"58.9","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.7","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"1272.2","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.6","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.8","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"1.8","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.8","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"2.5","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"6.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"95.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"72.9","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"3.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"45.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"49.6","Single Cell Type RNA - Hepatocytes [nTPM]":"4164.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"72.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"3.9","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"TBC1D4","Gene synonym":["AS160","DKFZp779C0666","KIAA0603"],"Ensembl":"ENSG00000136111","Gene description":"TBC1 domain family member 4","Uniprot":["O60343"],"Chromosome":"13","Position":"75283503-75482169","Protein class":["Disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":["Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"82.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"157.7","Microglial cells":"307.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"25.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"84.7","HUVEC TERT2":"61.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040145","HPA059885"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA040145":"AB_2676860","HPA059885":"AB_2684152"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.07e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Tissue RNA - adipose tissue [nTPM]":"14.8","Tissue RNA - adrenal gland [nTPM]":"70.6","Tissue RNA - amygdala [nTPM]":"13.2","Tissue RNA - appendix [nTPM]":"15.7","Tissue RNA - basal ganglia [nTPM]":"12.5","Tissue RNA - bone marrow [nTPM]":"3.4","Tissue RNA - breast [nTPM]":"20.1","Tissue RNA - cerebellum [nTPM]":"12.5","Tissue RNA - cerebral cortex [nTPM]":"15.1","Tissue RNA - cervix [nTPM]":"10.0","Tissue RNA - choroid plexus [nTPM]":"7.1","Tissue RNA - colon [nTPM]":"8.7","Tissue RNA - duodenum [nTPM]":"4.6","Tissue RNA - endometrium 1 [nTPM]":"8.5","Tissue RNA - epididymis [nTPM]":"18.4","Tissue RNA - esophagus [nTPM]":"9.4","Tissue RNA - fallopian tube [nTPM]":"10.7","Tissue RNA - gallbladder [nTPM]":"14.1","Tissue RNA - heart muscle [nTPM]":"33.8","Tissue RNA - hippocampal formation [nTPM]":"10.5","Tissue RNA - hypothalamus [nTPM]":"13.8","Tissue RNA - kidney [nTPM]":"25.2","Tissue RNA - liver [nTPM]":"11.7","Tissue RNA - lung [nTPM]":"11.9","Tissue RNA - lymph node [nTPM]":"34.2","Tissue RNA - medulla oblongata [nTPM]":"15.9","Tissue RNA - midbrain [nTPM]":"12.0","Tissue RNA - ovary [nTPM]":"44.8","Tissue RNA - pancreas [nTPM]":"15.0","Tissue RNA - parathyroid gland [nTPM]":"22.1","Tissue RNA - pituitary gland [nTPM]":"5.3","Tissue RNA - placenta [nTPM]":"20.7","Tissue RNA - pons [nTPM]":"16.7","Tissue RNA - prostate [nTPM]":"12.3","Tissue RNA - rectum [nTPM]":"10.4","Tissue RNA - retina [nTPM]":"1.6","Tissue RNA - salivary gland [nTPM]":"27.6","Tissue RNA - seminal vesicle [nTPM]":"4.3","Tissue RNA - skeletal muscle [nTPM]":"82.8","Tissue RNA - skin 1 [nTPM]":"21.4","Tissue RNA - small intestine [nTPM]":"10.3","Tissue RNA - smooth muscle [nTPM]":"10.2","Tissue RNA - spinal cord [nTPM]":"12.0","Tissue RNA - spleen [nTPM]":"21.0","Tissue RNA - stomach 1 [nTPM]":"11.0","Tissue RNA - testis [nTPM]":"5.3","Tissue RNA - thalamus [nTPM]":"20.0","Tissue RNA - thymus [nTPM]":"10.7","Tissue RNA - thyroid gland [nTPM]":"24.3","Tissue RNA - tongue [nTPM]":"54.9","Tissue RNA - tonsil [nTPM]":"32.6","Tissue RNA - urinary bladder [nTPM]":"8.4","Tissue RNA - vagina [nTPM]":"9.2","Tissue RNA - white matter [nTPM]":"10.5","Cell RNA - A-431 [nTPM]":"12.9","Cell RNA - A549 [nTPM]":"14.9","Cell RNA - AF22 [nTPM]":"9.2","Cell RNA - AN3-CA [nTPM]":"0.6","Cell RNA - ASC diff [nTPM]":"21.3","Cell RNA - ASC TERT1 [nTPM]":"22.8","Cell RNA - BEWO [nTPM]":"12.0","Cell RNA - BJ [nTPM]":"11.0","Cell RNA - BJ hTERT+ [nTPM]":"5.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.6","Cell RNA - CACO-2 [nTPM]":"84.7","Cell RNA - CAPAN-2 [nTPM]":"15.5","Cell RNA - Daudi [nTPM]":"2.7","Cell RNA - EFO-21 [nTPM]":"2.4","Cell RNA - fHDF\/TERT166 [nTPM]":"15.7","Cell RNA - GAMG [nTPM]":"4.2","Cell RNA - HaCaT [nTPM]":"12.0","Cell RNA - HAP1 [nTPM]":"23.4","Cell RNA - HBEC3-KT [nTPM]":"11.0","Cell RNA - HBF TERT88 [nTPM]":"9.0","Cell RNA - HDLM-2 [nTPM]":"42.6","Cell RNA - HEK 293 [nTPM]":"24.3","Cell RNA - HEL [nTPM]":"41.5","Cell RNA - HeLa [nTPM]":"19.8","Cell RNA - Hep G2 [nTPM]":"25.9","Cell RNA - HHSteC [nTPM]":"5.4","Cell RNA - HL-60 [nTPM]":"20.0","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"25.0","Cell RNA - hTCEpi [nTPM]":"19.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.7","Cell RNA - hTERT-HME1 [nTPM]":"22.4","Cell RNA - hTERT-RPE1 [nTPM]":"14.9","Cell RNA - HUVEC TERT2 [nTPM]":"61.6","Cell RNA - JURKAT [nTPM]":"46.0","Cell RNA - K-562 [nTPM]":"12.0","Cell RNA - Karpas-707 [nTPM]":"1.3","Cell RNA - LHCN-M2 [nTPM]":"10.0","Cell RNA - MCF7 [nTPM]":"6.2","Cell RNA - MOLT-4 [nTPM]":"29.4","Cell RNA - NB-4 [nTPM]":"3.6","Cell RNA - NTERA-2 [nTPM]":"12.9","Cell RNA - OE19 [nTPM]":"24.7","Cell RNA - PC-3 [nTPM]":"8.8","Cell RNA - REH [nTPM]":"26.4","Cell RNA - RH-30 [nTPM]":"8.7","Cell RNA - RPMI-8226 [nTPM]":"15.2","Cell RNA - RPTEC TERT1 [nTPM]":"8.5","Cell RNA - RT4 [nTPM]":"9.3","Cell RNA - SCLC-21H [nTPM]":"16.9","Cell RNA - SH-SY5Y [nTPM]":"5.2","Cell RNA - SiHa [nTPM]":"4.8","Cell RNA - SK-BR-3 [nTPM]":"14.6","Cell RNA - SK-MEL-30 [nTPM]":"8.0","Cell RNA - SuSa [nTPM]":"4.8","Cell RNA - T-47d [nTPM]":"5.0","Cell RNA - THP-1 [nTPM]":"0.7","Cell RNA - TIME [nTPM]":"26.2","Cell RNA - U-138 MG [nTPM]":"9.8","Cell RNA - U-2 OS [nTPM]":"12.1","Cell RNA - U-2197 [nTPM]":"5.2","Cell RNA - U-251 MG [nTPM]":"13.0","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"17.4","Cell RNA - U-937 [nTPM]":"18.5","Cell RNA - WM-115 [nTPM]":"14.7","Blood RNA - basophil [nTPM]":"5.0","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"11.2","Blood RNA - memory CD8 T-cell [nTPM]":"2.5","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"10.4","Blood RNA - naive CD8 T-cell [nTPM]":"4.9","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"9.9","Blood RNA - T-reg [nTPM]":"25.0","Blood RNA - total PBMC [nTPM]":"2.3","Brain RNA - amygdala [nTPM]":"13.2","Brain RNA - basal ganglia [nTPM]":"12.5","Brain RNA - cerebellum [nTPM]":"12.5","Brain RNA - cerebral cortex [nTPM]":"15.1","Brain RNA - hippocampal formation [nTPM]":"10.5","Brain RNA - hypothalamus [nTPM]":"13.8","Brain RNA - medulla oblongata [nTPM]":"15.9","Brain RNA - midbrain [nTPM]":"12.0","Brain RNA - pons [nTPM]":"16.7","Brain RNA - spinal cord [nTPM]":"12.0","Brain RNA - thalamus [nTPM]":"20.0","Brain RNA - white matter [nTPM]":"10.5","Single Cell Type RNA - Adipocytes [nTPM]":"17.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.1","Single Cell Type RNA - Astrocytes [nTPM]":"32.3","Single Cell Type RNA - B-cells [nTPM]":"2.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"36.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.9","Single Cell Type RNA - Bipolar cells [nTPM]":"1.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"33.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"41.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"81.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"6.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.8","Single Cell Type RNA - dendritic cells [nTPM]":"32.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"12.3","Single Cell Type RNA - Early spermatids [nTPM]":"25.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.7","Single Cell Type RNA - Endothelial cells [nTPM]":"32.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"78.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.7","Single Cell Type RNA - Fibroblasts [nTPM]":"17.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.7","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"81.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.0","Single Cell Type RNA - Hepatocytes [nTPM]":"19.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"26.6","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"157.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.7","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"24.8","Single Cell Type RNA - Langerhans cells [nTPM]":"25.8","Single Cell Type RNA - Late spermatids [nTPM]":"5.2","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"12.9","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"307.3","Single Cell Type RNA - monocytes [nTPM]":"33.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"40.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.9","Single Cell Type RNA - Paneth cells [nTPM]":"2.9","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"2.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"24.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.6","Single Cell Type RNA - Spermatocytes [nTPM]":"2.4","Single Cell Type RNA - Spermatogonia [nTPM]":"7.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"24.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"44.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.9","Single Cell Type RNA - T-cells [nTPM]":"25.2","Single Cell Type RNA - Theca cells [nTPM]":"8.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.5","Single Cell Type RNA - Urothelial cells [nTPM]":"10.6"},{"Gene":"TBCK","Gene synonym":["HSPC302","MGC16169"],"Ensembl":"ENSG00000145348","Gene description":"TBC1 domain containing kinase","Uniprot":["Q8TEA7"],"Chromosome":"4","Position":"106041599-106316683","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"134.8","Excitatory neurons":"196.6","Inhibitory neurons":"221.1","Microglial cells":"128.4","Oligodendrocyte precursor cells":"147.2","Oligodendrocytes":"188.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+ SV40 Large T+":"44.0","BJ hTERT+ SV40 Large T+ RasG12V":"81.7","HBF TERT88":"59.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039951","HPA051611"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm","Nucleoli fibrillar center"],"Subcellular additional location":null,"Antibody RRID":{"HPA039951":"AB_10795300","HPA051611":"AB_2681550"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.20e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.4","Tissue RNA - adrenal gland [nTPM]":"5.2","Tissue RNA - amygdala [nTPM]":"5.6","Tissue RNA - appendix [nTPM]":"3.0","Tissue RNA - basal ganglia [nTPM]":"5.3","Tissue RNA - bone marrow [nTPM]":"1.3","Tissue RNA - breast [nTPM]":"3.4","Tissue RNA - cerebellum [nTPM]":"11.0","Tissue RNA - cerebral cortex [nTPM]":"6.1","Tissue RNA - cervix [nTPM]":"4.5","Tissue RNA - choroid plexus [nTPM]":"8.3","Tissue RNA - colon [nTPM]":"3.2","Tissue RNA - duodenum [nTPM]":"2.3","Tissue RNA - endometrium 1 [nTPM]":"4.3","Tissue RNA - epididymis [nTPM]":"6.0","Tissue RNA - esophagus [nTPM]":"4.2","Tissue RNA - fallopian tube [nTPM]":"5.3","Tissue RNA - gallbladder [nTPM]":"5.6","Tissue RNA - heart muscle [nTPM]":"2.8","Tissue RNA - hippocampal formation [nTPM]":"6.1","Tissue RNA - hypothalamus [nTPM]":"7.0","Tissue RNA - kidney [nTPM]":"6.3","Tissue RNA - liver [nTPM]":"4.4","Tissue RNA - lung [nTPM]":"4.1","Tissue RNA - lymph node [nTPM]":"3.0","Tissue RNA - medulla oblongata [nTPM]":"5.2","Tissue RNA - midbrain [nTPM]":"5.3","Tissue RNA - ovary [nTPM]":"6.4","Tissue RNA - pancreas [nTPM]":"5.8","Tissue RNA - parathyroid gland [nTPM]":"4.8","Tissue RNA - pituitary gland [nTPM]":"3.9","Tissue RNA - placenta [nTPM]":"5.5","Tissue RNA - pons [nTPM]":"6.0","Tissue RNA - prostate [nTPM]":"4.7","Tissue RNA - rectum [nTPM]":"3.1","Tissue RNA - retina [nTPM]":"7.6","Tissue RNA - salivary gland [nTPM]":"3.6","Tissue RNA - seminal vesicle [nTPM]":"6.0","Tissue RNA - skeletal muscle [nTPM]":"1.6","Tissue RNA - skin 1 [nTPM]":"4.1","Tissue RNA - small intestine [nTPM]":"3.3","Tissue RNA - smooth muscle [nTPM]":"4.7","Tissue RNA - spinal cord [nTPM]":"3.5","Tissue RNA - spleen [nTPM]":"3.6","Tissue RNA - stomach 1 [nTPM]":"3.5","Tissue RNA - testis [nTPM]":"6.1","Tissue RNA - thalamus [nTPM]":"6.9","Tissue RNA - thymus [nTPM]":"4.7","Tissue RNA - thyroid gland [nTPM]":"5.5","Tissue RNA - tongue [nTPM]":"4.3","Tissue RNA - tonsil [nTPM]":"2.6","Tissue RNA - urinary bladder [nTPM]":"5.2","Tissue RNA - vagina [nTPM]":"3.0","Tissue RNA - white matter [nTPM]":"10.1","Cell RNA - A-431 [nTPM]":"1.4","Cell RNA - A549 [nTPM]":"5.9","Cell RNA - AF22 [nTPM]":"9.0","Cell RNA - AN3-CA [nTPM]":"2.7","Cell RNA - ASC diff [nTPM]":"36.7","Cell RNA - ASC TERT1 [nTPM]":"19.1","Cell RNA - BEWO [nTPM]":"1.1","Cell RNA - BJ [nTPM]":"8.1","Cell RNA - BJ hTERT+ [nTPM]":"8.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"44.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"81.7","Cell RNA - CACO-2 [nTPM]":"10.9","Cell RNA - CAPAN-2 [nTPM]":"6.4","Cell RNA - Daudi [nTPM]":"2.3","Cell RNA - EFO-21 [nTPM]":"13.0","Cell RNA - fHDF\/TERT166 [nTPM]":"28.0","Cell RNA - GAMG [nTPM]":"7.0","Cell RNA - HaCaT [nTPM]":"5.4","Cell RNA - HAP1 [nTPM]":"5.7","Cell RNA - HBEC3-KT [nTPM]":"8.1","Cell RNA - HBF TERT88 [nTPM]":"59.3","Cell RNA - HDLM-2 [nTPM]":"5.1","Cell RNA - HEK 293 [nTPM]":"1.8","Cell RNA - HEL [nTPM]":"14.1","Cell RNA - HeLa [nTPM]":"4.5","Cell RNA - Hep G2 [nTPM]":"10.3","Cell RNA - HHSteC [nTPM]":"9.7","Cell RNA - HL-60 [nTPM]":"2.7","Cell RNA - HMC-1 [nTPM]":"6.3","Cell RNA - HSkMC [nTPM]":"20.9","Cell RNA - hTCEpi [nTPM]":"5.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.1","Cell RNA - hTERT-HME1 [nTPM]":"7.1","Cell RNA - hTERT-RPE1 [nTPM]":"14.5","Cell RNA - HUVEC TERT2 [nTPM]":"11.1","Cell RNA - JURKAT [nTPM]":"6.0","Cell RNA - K-562 [nTPM]":"7.2","Cell RNA - Karpas-707 [nTPM]":"3.8","Cell RNA - LHCN-M2 [nTPM]":"10.2","Cell RNA - MCF7 [nTPM]":"7.7","Cell RNA - MOLT-4 [nTPM]":"5.2","Cell RNA - NB-4 [nTPM]":"3.7","Cell RNA - NTERA-2 [nTPM]":"2.0","Cell RNA - OE19 [nTPM]":"14.4","Cell RNA - PC-3 [nTPM]":"2.0","Cell RNA - REH [nTPM]":"4.1","Cell RNA - RH-30 [nTPM]":"3.7","Cell RNA - RPMI-8226 [nTPM]":"6.8","Cell RNA - RPTEC TERT1 [nTPM]":"11.1","Cell RNA - RT4 [nTPM]":"9.0","Cell RNA - SCLC-21H [nTPM]":"4.4","Cell RNA - SH-SY5Y [nTPM]":"4.1","Cell RNA - SiHa [nTPM]":"8.2","Cell RNA - SK-BR-3 [nTPM]":"4.0","Cell RNA - SK-MEL-30 [nTPM]":"5.6","Cell RNA - SuSa [nTPM]":"7.6","Cell RNA - T-47d [nTPM]":"4.8","Cell RNA - THP-1 [nTPM]":"8.5","Cell RNA - TIME [nTPM]":"8.3","Cell RNA - U-138 MG [nTPM]":"7.7","Cell RNA - U-2 OS [nTPM]":"4.3","Cell RNA - U-2197 [nTPM]":"2.4","Cell RNA - U-251 MG [nTPM]":"4.4","Cell RNA - U-266\/70 [nTPM]":"2.5","Cell RNA - U-266\/84 [nTPM]":"6.1","Cell RNA - U-698 [nTPM]":"6.8","Cell RNA - U-87 MG [nTPM]":"10.1","Cell RNA - U-937 [nTPM]":"5.6","Cell RNA - WM-115 [nTPM]":"5.0","Blood RNA - basophil [nTPM]":"14.1","Blood RNA - classical monocyte [nTPM]":"5.1","Blood RNA - eosinophil [nTPM]":"5.1","Blood RNA - gdT-cell [nTPM]":"4.7","Blood RNA - intermediate monocyte [nTPM]":"5.7","Blood RNA - MAIT T-cell [nTPM]":"5.6","Blood RNA - memory B-cell [nTPM]":"4.8","Blood RNA - memory CD4 T-cell [nTPM]":"4.9","Blood RNA - memory CD8 T-cell [nTPM]":"6.4","Blood RNA - myeloid DC [nTPM]":"4.8","Blood RNA - naive B-cell [nTPM]":"7.9","Blood RNA - naive CD4 T-cell [nTPM]":"5.6","Blood RNA - naive CD8 T-cell [nTPM]":"5.2","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"5.2","Blood RNA - non-classical monocyte [nTPM]":"3.8","Blood RNA - plasmacytoid DC [nTPM]":"4.4","Blood RNA - T-reg [nTPM]":"5.5","Blood RNA - total PBMC [nTPM]":"4.0","Brain RNA - amygdala [nTPM]":"5.6","Brain RNA - basal ganglia [nTPM]":"5.3","Brain RNA - cerebellum [nTPM]":"11.0","Brain RNA - cerebral cortex [nTPM]":"6.1","Brain RNA - hippocampal formation [nTPM]":"6.1","Brain RNA - hypothalamus [nTPM]":"7.0","Brain RNA - medulla oblongata [nTPM]":"5.2","Brain RNA - midbrain [nTPM]":"5.3","Brain RNA - pons [nTPM]":"6.0","Brain RNA - spinal cord [nTPM]":"3.5","Brain RNA - thalamus [nTPM]":"6.9","Brain RNA - white matter [nTPM]":"10.1","Single Cell Type RNA - Adipocytes [nTPM]":"7.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.2","Single Cell Type RNA - Astrocytes [nTPM]":"134.8","Single Cell Type RNA - B-cells [nTPM]":"13.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Bipolar cells [nTPM]":"20.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"15.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.5","Single Cell Type RNA - dendritic cells [nTPM]":"9.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.3","Single Cell Type RNA - Early spermatids [nTPM]":"45.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.9","Single Cell Type RNA - Endothelial cells [nTPM]":"8.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"9.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"196.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.6","Single Cell Type RNA - Fibroblasts [nTPM]":"12.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.1","Single Cell Type RNA - granulocytes [nTPM]":"11.4","Single Cell Type RNA - Granulosa cells [nTPM]":"21.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.6","Single Cell Type RNA - Hepatocytes [nTPM]":"4.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.8","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"221.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.7","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"6.2","Single Cell Type RNA - Langerhans cells [nTPM]":"1.6","Single Cell Type RNA - Late spermatids [nTPM]":"28.2","Single Cell Type RNA - Leydig cells [nTPM]":"11.1","Single Cell Type RNA - Macrophages [nTPM]":"7.7","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"128.4","Single Cell Type RNA - monocytes [nTPM]":"4.6","Single Cell Type RNA - Muller glia cells [nTPM]":"8.1","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"147.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"188.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.2","Single Cell Type RNA - Paneth cells [nTPM]":"8.0","Single Cell Type RNA - Peritubular cells [nTPM]":"12.8","Single Cell Type RNA - Plasma cells [nTPM]":"10.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.6","Single Cell Type RNA - Spermatocytes [nTPM]":"14.5","Single Cell Type RNA - Spermatogonia [nTPM]":"8.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.4","Single Cell Type RNA - T-cells [nTPM]":"10.6","Single Cell Type RNA - Theca cells [nTPM]":"13.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.5","Single Cell Type RNA - Urothelial cells [nTPM]":"4.5"},{"Gene":"TBK1","Gene synonym":["NAK"],"Ensembl":"ENSG00000183735","Gene description":"TANK binding kinase 1","Uniprot":["Q9UHD2"],"Chromosome":"12","Position":"64452090-64502114","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["Antiviral defense","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Amyotrophic lateral sclerosis","Disease variant","Glaucoma","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045797","HPA060211"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA045797":"AB_2679457","HPA060211":"AB_2684222"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.30e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.48e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.20e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-3"},"Tissue RNA - adipose tissue [nTPM]":"11.6","Tissue RNA - adrenal gland [nTPM]":"15.3","Tissue RNA - amygdala [nTPM]":"6.0","Tissue RNA - appendix [nTPM]":"10.1","Tissue RNA - basal ganglia [nTPM]":"6.1","Tissue RNA - bone marrow [nTPM]":"16.9","Tissue RNA - breast [nTPM]":"11.4","Tissue RNA - cerebellum [nTPM]":"5.6","Tissue RNA - cerebral cortex [nTPM]":"6.9","Tissue RNA - cervix [nTPM]":"10.6","Tissue RNA - choroid plexus [nTPM]":"5.3","Tissue RNA - colon [nTPM]":"10.5","Tissue RNA - duodenum [nTPM]":"15.1","Tissue RNA - endometrium 1 [nTPM]":"11.0","Tissue RNA - epididymis [nTPM]":"6.7","Tissue RNA - esophagus [nTPM]":"11.3","Tissue RNA - fallopian tube [nTPM]":"9.5","Tissue RNA - gallbladder [nTPM]":"10.1","Tissue RNA - heart muscle [nTPM]":"9.4","Tissue RNA - hippocampal formation [nTPM]":"5.8","Tissue RNA - hypothalamus [nTPM]":"5.6","Tissue RNA - kidney [nTPM]":"11.8","Tissue RNA - liver [nTPM]":"17.4","Tissue RNA - lung [nTPM]":"12.9","Tissue RNA - lymph node [nTPM]":"14.6","Tissue RNA - medulla oblongata [nTPM]":"6.5","Tissue RNA - midbrain [nTPM]":"6.9","Tissue RNA - ovary [nTPM]":"9.6","Tissue RNA - pancreas [nTPM]":"7.5","Tissue RNA - parathyroid gland [nTPM]":"11.6","Tissue RNA - pituitary gland [nTPM]":"9.8","Tissue RNA - placenta [nTPM]":"13.7","Tissue RNA - pons [nTPM]":"6.1","Tissue RNA - prostate [nTPM]":"10.6","Tissue RNA - rectum [nTPM]":"8.5","Tissue RNA - retina [nTPM]":"6.3","Tissue RNA - salivary gland [nTPM]":"10.2","Tissue RNA - seminal vesicle [nTPM]":"9.0","Tissue RNA - skeletal muscle [nTPM]":"18.4","Tissue RNA - skin 1 [nTPM]":"8.6","Tissue RNA - small intestine [nTPM]":"11.4","Tissue RNA - smooth muscle [nTPM]":"10.8","Tissue RNA - spinal cord [nTPM]":"5.3","Tissue RNA - spleen [nTPM]":"13.4","Tissue RNA - stomach 1 [nTPM]":"10.2","Tissue RNA - testis [nTPM]":"23.5","Tissue RNA - thalamus [nTPM]":"6.7","Tissue RNA - thymus [nTPM]":"6.8","Tissue RNA - thyroid gland [nTPM]":"8.5","Tissue RNA - tongue [nTPM]":"14.9","Tissue RNA - tonsil [nTPM]":"12.9","Tissue RNA - urinary bladder [nTPM]":"16.0","Tissue RNA - vagina [nTPM]":"10.2","Tissue RNA - white matter [nTPM]":"7.1","Cell RNA - A-431 [nTPM]":"23.3","Cell RNA - A549 [nTPM]":"24.2","Cell RNA - AF22 [nTPM]":"11.1","Cell RNA - AN3-CA [nTPM]":"10.6","Cell RNA - ASC diff [nTPM]":"24.7","Cell RNA - ASC TERT1 [nTPM]":"26.1","Cell RNA - BEWO [nTPM]":"29.0","Cell RNA - BJ [nTPM]":"22.9","Cell RNA - BJ hTERT+ [nTPM]":"37.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"22.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.1","Cell RNA - CACO-2 [nTPM]":"14.9","Cell RNA - CAPAN-2 [nTPM]":"12.4","Cell RNA - Daudi [nTPM]":"31.5","Cell RNA - EFO-21 [nTPM]":"21.4","Cell RNA - fHDF\/TERT166 [nTPM]":"26.8","Cell RNA - GAMG [nTPM]":"34.4","Cell RNA - HaCaT [nTPM]":"19.0","Cell RNA - HAP1 [nTPM]":"19.4","Cell RNA - HBEC3-KT [nTPM]":"20.0","Cell RNA - HBF TERT88 [nTPM]":"26.4","Cell RNA - HDLM-2 [nTPM]":"29.5","Cell RNA - HEK 293 [nTPM]":"17.1","Cell RNA - HEL [nTPM]":"33.0","Cell RNA - HeLa [nTPM]":"15.3","Cell RNA - Hep G2 [nTPM]":"19.1","Cell RNA - HHSteC [nTPM]":"30.2","Cell RNA - HL-60 [nTPM]":"35.2","Cell RNA - HMC-1 [nTPM]":"36.4","Cell RNA - HSkMC [nTPM]":"18.5","Cell RNA - hTCEpi [nTPM]":"19.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"23.1","Cell RNA - hTERT-HME1 [nTPM]":"23.6","Cell RNA - hTERT-RPE1 [nTPM]":"42.3","Cell RNA - HUVEC TERT2 [nTPM]":"32.4","Cell RNA - JURKAT [nTPM]":"11.0","Cell RNA - K-562 [nTPM]":"27.9","Cell RNA - Karpas-707 [nTPM]":"38.7","Cell RNA - LHCN-M2 [nTPM]":"31.6","Cell RNA - MCF7 [nTPM]":"27.0","Cell RNA - MOLT-4 [nTPM]":"0.9","Cell RNA - NB-4 [nTPM]":"17.0","Cell RNA - NTERA-2 [nTPM]":"29.9","Cell RNA - OE19 [nTPM]":"22.9","Cell RNA - PC-3 [nTPM]":"13.8","Cell RNA - REH [nTPM]":"14.9","Cell RNA - RH-30 [nTPM]":"15.3","Cell RNA - RPMI-8226 [nTPM]":"31.8","Cell RNA - RPTEC TERT1 [nTPM]":"25.1","Cell RNA - RT4 [nTPM]":"36.9","Cell RNA - SCLC-21H [nTPM]":"9.8","Cell RNA - SH-SY5Y [nTPM]":"14.7","Cell RNA - SiHa [nTPM]":"33.3","Cell RNA - SK-BR-3 [nTPM]":"36.0","Cell RNA - SK-MEL-30 [nTPM]":"23.5","Cell RNA - SuSa [nTPM]":"23.5","Cell RNA - T-47d [nTPM]":"33.1","Cell RNA - THP-1 [nTPM]":"24.9","Cell RNA - TIME [nTPM]":"25.9","Cell RNA - U-138 MG [nTPM]":"20.2","Cell RNA - U-2 OS [nTPM]":"18.1","Cell RNA - U-2197 [nTPM]":"14.9","Cell RNA - U-251 MG [nTPM]":"24.0","Cell RNA - U-266\/70 [nTPM]":"25.4","Cell RNA - U-266\/84 [nTPM]":"54.3","Cell RNA - U-698 [nTPM]":"30.3","Cell RNA - U-87 MG [nTPM]":"28.1","Cell RNA - U-937 [nTPM]":"18.6","Cell RNA - WM-115 [nTPM]":"26.1","Blood RNA - basophil [nTPM]":"41.8","Blood RNA - classical monocyte [nTPM]":"10.1","Blood RNA - eosinophil [nTPM]":"24.3","Blood RNA - gdT-cell [nTPM]":"13.9","Blood RNA - intermediate monocyte [nTPM]":"17.7","Blood RNA - MAIT T-cell [nTPM]":"16.3","Blood RNA - memory B-cell [nTPM]":"12.8","Blood RNA - memory CD4 T-cell [nTPM]":"10.1","Blood RNA - memory CD8 T-cell [nTPM]":"15.2","Blood RNA - myeloid DC [nTPM]":"12.2","Blood RNA - naive B-cell [nTPM]":"10.1","Blood RNA - naive CD4 T-cell [nTPM]":"2.8","Blood RNA - naive CD8 T-cell [nTPM]":"8.7","Blood RNA - neutrophil [nTPM]":"17.8","Blood RNA - NK-cell [nTPM]":"26.6","Blood RNA - non-classical monocyte [nTPM]":"15.5","Blood RNA - plasmacytoid DC [nTPM]":"2.1","Blood RNA - T-reg [nTPM]":"13.6","Blood RNA - total PBMC [nTPM]":"10.0","Brain RNA - amygdala [nTPM]":"6.0","Brain RNA - basal ganglia [nTPM]":"6.1","Brain RNA - cerebellum [nTPM]":"5.6","Brain RNA - cerebral cortex [nTPM]":"6.9","Brain RNA - hippocampal formation [nTPM]":"5.8","Brain RNA - hypothalamus [nTPM]":"5.6","Brain RNA - medulla oblongata [nTPM]":"6.5","Brain RNA - midbrain [nTPM]":"6.9","Brain RNA - pons [nTPM]":"6.1","Brain RNA - spinal cord [nTPM]":"5.3","Brain RNA - thalamus [nTPM]":"6.7","Brain RNA - white matter [nTPM]":"7.1","Single Cell Type RNA - Adipocytes [nTPM]":"23.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.5","Single Cell Type RNA - Astrocytes [nTPM]":"28.4","Single Cell Type RNA - B-cells [nTPM]":"21.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"25.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"20.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Bipolar cells [nTPM]":"17.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"23.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"28.8","Single Cell Type RNA - dendritic cells [nTPM]":"30.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"19.3","Single Cell Type RNA - Early spermatids [nTPM]":"34.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.9","Single Cell Type RNA - Endothelial cells [nTPM]":"28.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.3","Single Cell Type RNA - Erythroid cells [nTPM]":"18.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"50.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"32.6","Single Cell Type RNA - Fibroblasts [nTPM]":"21.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"30.2","Single Cell Type RNA - granulocytes [nTPM]":"43.1","Single Cell Type RNA - Granulosa cells [nTPM]":"17.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.8","Single Cell Type RNA - Hepatocytes [nTPM]":"17.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.2","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"42.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.5","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"23.0","Single Cell Type RNA - Langerhans cells [nTPM]":"30.2","Single Cell Type RNA - Late spermatids [nTPM]":"29.2","Single Cell Type RNA - Leydig cells [nTPM]":"19.3","Single Cell Type RNA - Macrophages [nTPM]":"31.1","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"46.9","Single Cell Type RNA - monocytes [nTPM]":"31.4","Single Cell Type RNA - Muller glia cells [nTPM]":"12.7","Single Cell Type RNA - NK-cells [nTPM]":"33.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"39.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"52.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.9","Single Cell Type RNA - Paneth cells [nTPM]":"10.9","Single Cell Type RNA - Peritubular cells [nTPM]":"20.7","Single Cell Type RNA - Plasma cells [nTPM]":"25.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"43.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.3","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.7","Single Cell Type RNA - Spermatocytes [nTPM]":"68.9","Single Cell Type RNA - Spermatogonia [nTPM]":"12.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"92.6","Single Cell Type RNA - T-cells [nTPM]":"27.1","Single Cell Type RNA - Theca cells [nTPM]":"11.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.1","Single Cell Type RNA - Urothelial cells [nTPM]":"41.6"},{"Gene":"TDO2","Gene synonym":["TDO","TPH2"],"Ensembl":"ENSG00000151790","Gene description":"Tryptophan 2,3-dioxygenase","Uniprot":["P48775"],"Chromosome":"4","Position":"155854738-155920406","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Tryptophan catabolism"],"Molecular function":["Dioxygenase","Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"47","RNA tissue specific nTPM":{"liver":"797.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Hepatocytes":"1174.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"18","RNA cancer specific FPKM":{"liver cancer":"35.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"EFO-21":"9.6","HDLM-2":"22.0","U-87 MG":"11.3"},"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"7","RNA mouse brain regional specific nTPM":{"cerebellum":"6.3","hippocampal formation":"5.3","white matter":"1.9"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039611"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA039611":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"1.6","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"16.8","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"1.2","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"1.2","Tissue RNA - duodenum [nTPM]":"3.5","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"0.7","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"1.9","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"797.8","Tissue RNA - lung [nTPM]":"3.2","Tissue RNA - lymph node [nTPM]":"3.1","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"1.1","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"4.0","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"1.4","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"5.9","Tissue RNA - smooth muscle [nTPM]":"2.5","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"1.9","Tissue RNA - stomach 1 [nTPM]":"1.6","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"2.6","Tissue RNA - urinary bladder [nTPM]":"7.6","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"1.9","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"1.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"9.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"22.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"1.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"3.5","Cell RNA - LHCN-M2 [nTPM]":"0.3","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.9","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"1.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"1.2","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"3.4","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"11.3","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"1.2","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"1.1","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"2.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"158.7","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.1","Single Cell Type RNA - Endothelial cells [nTPM]":"2.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"32.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"29.6","Single Cell Type RNA - Hepatocytes [nTPM]":"1174.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"31.7","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"1.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"2.3","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"TDRD9","Gene synonym":["C14orf75","DKFZp434N0820","FLJ36164","NET54"],"Ensembl":"ENSG00000156414","Gene description":"Tudor domain containing 9","Uniprot":["Q8NDG6"],"Chromosome":"14","Position":"103928456-104052667","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Differentiation","Meiosis","RNA-mediated gene silencing","Spermatogenesis"],"Molecular function":["Developmental protein","Helicase","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"parathyroid gland":"30.6","testis":"40.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"43.2","Spermatocytes":"63.2","Spermatogonia":"38.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"classical monocyte":"1.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"monocytes":"1.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"24.4","HeLa":"21.5","HMC-1":"94.2","RPTEC TERT1":"25.5","SK-MEL-30":"13.3"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.52e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"0.9","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"0.8","Tissue RNA - bone marrow [nTPM]":"1.7","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"1.3","Tissue RNA - cerebral cortex [nTPM]":"0.9","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"1.2","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"0.9","Tissue RNA - heart muscle [nTPM]":"0.6","Tissue RNA - hippocampal formation [nTPM]":"0.8","Tissue RNA - hypothalamus [nTPM]":"0.8","Tissue RNA - kidney [nTPM]":"2.1","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"1.7","Tissue RNA - midbrain [nTPM]":"1.0","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.5","Tissue RNA - parathyroid gland [nTPM]":"30.6","Tissue RNA - pituitary gland [nTPM]":"1.0","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"2.0","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"3.5","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.5","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"3.0","Tissue RNA - stomach 1 [nTPM]":"0.8","Tissue RNA - testis [nTPM]":"40.7","Tissue RNA - thalamus [nTPM]":"1.1","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"5.4","Tissue RNA - tongue [nTPM]":"0.5","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"1.3","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"3.8","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"24.4","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"21.5","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"94.2","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.6","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"1.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"25.5","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"8.7","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"13.3","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.6","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"0.9","Brain RNA - basal ganglia [nTPM]":"0.8","Brain RNA - cerebellum [nTPM]":"1.3","Brain RNA - cerebral cortex [nTPM]":"0.9","Brain RNA - hippocampal formation [nTPM]":"0.8","Brain RNA - hypothalamus [nTPM]":"0.8","Brain RNA - medulla oblongata [nTPM]":"1.7","Brain RNA - midbrain [nTPM]":"1.0","Brain RNA - pons [nTPM]":"2.0","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"1.1","Brain RNA - white matter [nTPM]":"1.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"4.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.6","Single Cell Type RNA - Early spermatids [nTPM]":"13.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"43.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.5","Single Cell Type RNA - Endothelial cells [nTPM]":"0.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.9","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"7.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"1.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"2.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.8","Single Cell Type RNA - Spermatocytes [nTPM]":"63.2","Single Cell Type RNA - Spermatogonia [nTPM]":"38.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"11.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"TECR","Gene synonym":["GPSN2","MRT14","SC2","TER"],"Ensembl":"ENSG00000099797","Gene description":"Trans-2,3-enoyl-CoA reductase","Uniprot":["Q9NZ01"],"Chromosome":"19","Position":"14517085-14565980","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"1013.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029780","HPA056488"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"10000","Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA029780":"AB_10603348","HPA056488":"AB_2683149"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.60e-4"},"Tissue RNA - adipose tissue [nTPM]":"102.7","Tissue RNA - adrenal gland [nTPM]":"162.6","Tissue RNA - amygdala [nTPM]":"189.0","Tissue RNA - appendix [nTPM]":"43.1","Tissue RNA - basal ganglia [nTPM]":"201.7","Tissue RNA - bone marrow [nTPM]":"74.2","Tissue RNA - breast [nTPM]":"100.4","Tissue RNA - cerebellum [nTPM]":"220.8","Tissue RNA - cerebral cortex [nTPM]":"237.5","Tissue RNA - cervix [nTPM]":"156.8","Tissue RNA - choroid plexus [nTPM]":"216.5","Tissue RNA - colon [nTPM]":"78.5","Tissue RNA - duodenum [nTPM]":"106.1","Tissue RNA - endometrium 1 [nTPM]":"53.2","Tissue RNA - epididymis [nTPM]":"103.2","Tissue RNA - esophagus [nTPM]":"373.2","Tissue RNA - fallopian tube [nTPM]":"87.1","Tissue RNA - gallbladder [nTPM]":"49.7","Tissue RNA - heart muscle [nTPM]":"78.4","Tissue RNA - hippocampal formation [nTPM]":"180.1","Tissue RNA - hypothalamus [nTPM]":"200.0","Tissue RNA - kidney [nTPM]":"112.2","Tissue RNA - liver [nTPM]":"133.9","Tissue RNA - lung [nTPM]":"67.8","Tissue RNA - lymph node [nTPM]":"55.7","Tissue RNA - medulla oblongata [nTPM]":"209.6","Tissue RNA - midbrain [nTPM]":"191.2","Tissue RNA - ovary [nTPM]":"80.9","Tissue RNA - pancreas [nTPM]":"105.5","Tissue RNA - parathyroid gland [nTPM]":"306.1","Tissue RNA - pituitary gland [nTPM]":"78.7","Tissue RNA - placenta [nTPM]":"68.0","Tissue RNA - pons [nTPM]":"212.2","Tissue RNA - prostate [nTPM]":"85.7","Tissue RNA - rectum [nTPM]":"59.3","Tissue RNA - retina [nTPM]":"82.8","Tissue RNA - salivary gland [nTPM]":"222.3","Tissue RNA - seminal vesicle [nTPM]":"83.5","Tissue RNA - skeletal muscle [nTPM]":"366.3","Tissue RNA - skin 1 [nTPM]":"263.5","Tissue RNA - small intestine [nTPM]":"95.9","Tissue RNA - smooth muscle [nTPM]":"36.7","Tissue RNA - spinal cord [nTPM]":"207.6","Tissue RNA - spleen [nTPM]":"75.4","Tissue RNA - stomach 1 [nTPM]":"81.7","Tissue RNA - testis [nTPM]":"182.7","Tissue RNA - thalamus [nTPM]":"199.9","Tissue RNA - thymus [nTPM]":"65.8","Tissue RNA - thyroid gland [nTPM]":"92.7","Tissue RNA - tongue [nTPM]":"209.6","Tissue RNA - tonsil [nTPM]":"85.3","Tissue RNA - urinary bladder [nTPM]":"51.6","Tissue RNA - vagina [nTPM]":"185.9","Tissue RNA - white matter [nTPM]":"230.2","Cell RNA - A-431 [nTPM]":"220.5","Cell RNA - A549 [nTPM]":"162.1","Cell RNA - AF22 [nTPM]":"149.5","Cell RNA - AN3-CA [nTPM]":"169.6","Cell RNA - ASC diff [nTPM]":"214.7","Cell RNA - ASC TERT1 [nTPM]":"97.2","Cell RNA - BEWO [nTPM]":"156.9","Cell RNA - BJ [nTPM]":"62.8","Cell RNA - BJ hTERT+ [nTPM]":"175.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"196.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"242.9","Cell RNA - CACO-2 [nTPM]":"225.3","Cell RNA - CAPAN-2 [nTPM]":"246.2","Cell RNA - Daudi [nTPM]":"113.8","Cell RNA - EFO-21 [nTPM]":"127.4","Cell RNA - fHDF\/TERT166 [nTPM]":"134.2","Cell RNA - GAMG [nTPM]":"152.4","Cell RNA - HaCaT [nTPM]":"328.8","Cell RNA - HAP1 [nTPM]":"158.1","Cell RNA - HBEC3-KT [nTPM]":"254.3","Cell RNA - HBF TERT88 [nTPM]":"84.0","Cell RNA - HDLM-2 [nTPM]":"192.3","Cell RNA - HEK 293 [nTPM]":"165.9","Cell RNA - HEL [nTPM]":"193.7","Cell RNA - HeLa [nTPM]":"225.4","Cell RNA - Hep G2 [nTPM]":"254.6","Cell RNA - HHSteC [nTPM]":"129.7","Cell RNA - HL-60 [nTPM]":"139.5","Cell RNA - HMC-1 [nTPM]":"143.7","Cell RNA - HSkMC [nTPM]":"144.9","Cell RNA - hTCEpi [nTPM]":"201.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"174.3","Cell RNA - hTERT-HME1 [nTPM]":"96.1","Cell RNA - hTERT-RPE1 [nTPM]":"98.4","Cell RNA - HUVEC TERT2 [nTPM]":"93.7","Cell RNA - JURKAT [nTPM]":"169.2","Cell RNA - K-562 [nTPM]":"128.9","Cell RNA - Karpas-707 [nTPM]":"391.5","Cell RNA - LHCN-M2 [nTPM]":"104.0","Cell RNA - MCF7 [nTPM]":"289.3","Cell RNA - MOLT-4 [nTPM]":"170.1","Cell RNA - NB-4 [nTPM]":"248.3","Cell RNA - NTERA-2 [nTPM]":"155.6","Cell RNA - OE19 [nTPM]":"556.1","Cell RNA - PC-3 [nTPM]":"227.6","Cell RNA - REH [nTPM]":"154.4","Cell RNA - RH-30 [nTPM]":"96.1","Cell RNA - RPMI-8226 [nTPM]":"521.1","Cell RNA - RPTEC TERT1 [nTPM]":"275.1","Cell RNA - RT4 [nTPM]":"115.8","Cell RNA - SCLC-21H [nTPM]":"183.2","Cell RNA - SH-SY5Y [nTPM]":"113.0","Cell RNA - SiHa [nTPM]":"103.1","Cell RNA - SK-BR-3 [nTPM]":"278.4","Cell RNA - SK-MEL-30 [nTPM]":"139.6","Cell RNA - SuSa [nTPM]":"77.2","Cell RNA - T-47d [nTPM]":"151.3","Cell RNA - THP-1 [nTPM]":"274.4","Cell RNA - TIME [nTPM]":"55.2","Cell RNA - U-138 MG [nTPM]":"160.5","Cell RNA - U-2 OS [nTPM]":"66.8","Cell RNA - U-2197 [nTPM]":"141.0","Cell RNA - U-251 MG [nTPM]":"212.6","Cell RNA - U-266\/70 [nTPM]":"118.4","Cell RNA - U-266\/84 [nTPM]":"119.8","Cell RNA - U-698 [nTPM]":"122.7","Cell RNA - U-87 MG [nTPM]":"163.8","Cell RNA - U-937 [nTPM]":"212.6","Cell RNA - WM-115 [nTPM]":"162.2","Blood RNA - basophil [nTPM]":"55.6","Blood RNA - classical monocyte [nTPM]":"72.7","Blood RNA - eosinophil [nTPM]":"52.5","Blood RNA - gdT-cell [nTPM]":"137.8","Blood RNA - intermediate monocyte [nTPM]":"106.4","Blood RNA - MAIT T-cell [nTPM]":"148.8","Blood RNA - memory B-cell [nTPM]":"100.1","Blood RNA - memory CD4 T-cell [nTPM]":"180.1","Blood RNA - memory CD8 T-cell [nTPM]":"159.1","Blood RNA - myeloid DC [nTPM]":"124.2","Blood RNA - naive B-cell [nTPM]":"99.1","Blood RNA - naive CD4 T-cell [nTPM]":"207.1","Blood RNA - naive CD8 T-cell [nTPM]":"164.5","Blood RNA - neutrophil [nTPM]":"32.7","Blood RNA - NK-cell [nTPM]":"183.7","Blood RNA - non-classical monocyte [nTPM]":"83.9","Blood RNA - plasmacytoid DC [nTPM]":"137.1","Blood RNA - T-reg [nTPM]":"290.1","Blood RNA - total PBMC [nTPM]":"170.9","Brain RNA - amygdala [nTPM]":"189.0","Brain RNA - basal ganglia [nTPM]":"201.7","Brain RNA - cerebellum [nTPM]":"220.8","Brain RNA - cerebral cortex [nTPM]":"237.5","Brain RNA - hippocampal formation [nTPM]":"180.1","Brain RNA - hypothalamus [nTPM]":"200.0","Brain RNA - medulla oblongata [nTPM]":"209.6","Brain RNA - midbrain [nTPM]":"191.2","Brain RNA - pons [nTPM]":"212.2","Brain RNA - spinal cord [nTPM]":"207.6","Brain RNA - thalamus [nTPM]":"199.9","Brain RNA - white matter [nTPM]":"230.2","Single Cell Type RNA - Adipocytes [nTPM]":"60.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"73.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"71.1","Single Cell Type RNA - Astrocytes [nTPM]":"47.7","Single Cell Type RNA - B-cells [nTPM]":"87.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"169.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"227.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"297.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"125.7","Single Cell Type RNA - Bipolar cells [nTPM]":"90.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"161.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"155.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"52.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"120.1","Single Cell Type RNA - Club cells [nTPM]":"221.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"165.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"123.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"509.5","Single Cell Type RNA - dendritic cells [nTPM]":"88.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"159.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"56.7","Single Cell Type RNA - Ductal cells [nTPM]":"166.2","Single Cell Type RNA - Early spermatids [nTPM]":"443.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"102.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"40.1","Single Cell Type RNA - Endothelial cells [nTPM]":"64.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"100.0","Single Cell Type RNA - Erythroid cells [nTPM]":"80.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"225.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"525.5","Single Cell Type RNA - Fibroblasts [nTPM]":"81.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"89.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"64.2","Single Cell Type RNA - granulocytes [nTPM]":"36.1","Single Cell Type RNA - Granulosa cells [nTPM]":"90.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"73.2","Single Cell Type RNA - Hepatocytes [nTPM]":"143.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"188.0","Single Cell Type RNA - Horizontal cells [nTPM]":"112.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"19.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"144.0","Single Cell Type RNA - Ionocytes [nTPM]":"199.4","Single Cell Type RNA - Kupffer cells [nTPM]":"113.8","Single Cell Type RNA - Langerhans cells [nTPM]":"99.3","Single Cell Type RNA - Late spermatids [nTPM]":"1013.1","Single Cell Type RNA - Leydig cells [nTPM]":"72.7","Single Cell Type RNA - Macrophages [nTPM]":"77.8","Single Cell Type RNA - Melanocytes [nTPM]":"163.7","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"61.6","Single Cell Type RNA - Muller glia cells [nTPM]":"577.9","Single Cell Type RNA - NK-cells [nTPM]":"103.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"46.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"104.8","Single Cell Type RNA - Paneth cells [nTPM]":"128.2","Single Cell Type RNA - Peritubular cells [nTPM]":"60.2","Single Cell Type RNA - Plasma cells [nTPM]":"206.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"110.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"343.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"202.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"213.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"177.5","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"68.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"286.7","Single Cell Type RNA - Spermatocytes [nTPM]":"215.0","Single Cell Type RNA - Spermatogonia [nTPM]":"134.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"255.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"239.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"486.2","Single Cell Type RNA - T-cells [nTPM]":"117.7","Single Cell Type RNA - Theca cells [nTPM]":"116.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"216.2","Single Cell Type RNA - Urothelial cells [nTPM]":"196.5"},{"Gene":"TERT","Gene synonym":["EST2","hEST2","TCS1","TP2","TRT"],"Ensembl":"ENSG00000164362","Gene description":"Telomerase reverse transcriptase","Uniprot":["O14746"],"Chromosome":"5","Position":"1253147-1295068","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["DNA-binding","Nucleotidyltransferase","Ribonucleoprotein","RNA-directed DNA polymerase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Dyskeratosis congenita"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"1.4","Intestinal goblet cells":"1.0","Plasma cells":"2.8","Spermatocytes":"1.5","Spermatogonia":"4.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC TERT1":"438.0","fHDF\/TERT166":"429.4","HBEC3-KT":"929.2","hTEC\/SVTERT24-B":"560.1","LHCN-M2":"252.2","TIME":"799.9"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054641","HPA065897"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear speckles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear speckles","Cytosol"],"Antibody RRID":{"HPA054641":"AB_2682554","HPA065897":"AB_2685576"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.5","Cell RNA - ASC diff [nTPM]":"213.2","Cell RNA - ASC TERT1 [nTPM]":"438.0","Cell RNA - BEWO [nTPM]":"3.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"173.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"31.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"59.4","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"3.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"429.4","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"1.0","Cell RNA - HBEC3-KT [nTPM]":"929.2","Cell RNA - HBF TERT88 [nTPM]":"29.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.7","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.4","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"1.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"22.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"560.1","Cell RNA - hTERT-HME1 [nTPM]":"6.8","Cell RNA - hTERT-RPE1 [nTPM]":"1.3","Cell RNA - HUVEC TERT2 [nTPM]":"1.5","Cell RNA - JURKAT [nTPM]":"1.8","Cell RNA - K-562 [nTPM]":"2.9","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"252.2","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"9.4","Cell RNA - NTERA-2 [nTPM]":"2.9","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"1.3","Cell RNA - REH [nTPM]":"2.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"5.4","Cell RNA - RPTEC TERT1 [nTPM]":"23.9","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"2.1","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"799.9","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"0.5","Cell RNA - U-698 [nTPM]":"0.7","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"4.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"TET1","Gene synonym":["bA119F7.1","CXXC6","KIAA1676","LCX"],"Ensembl":"ENSG00000138336","Gene description":"Tet methylcytosine dioxygenase 1","Uniprot":["Q8NFU7"],"Chromosome":"10","Position":"68560337-68694487","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","Chromatin regulator","Dioxygenase","DNA-binding","Oxidoreductase","Repressor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"4.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"54.5","Extravillous trophoblasts":"79.9","Oligodendrocyte precursor cells":"44.7","Oligodendrocytes":"45.3","Theca cells":"43.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"15","RNA cancer specific FPKM":{"testis cancer":"10.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"17.7","HAP1":"20.4","K-562":"12.0","NTERA-2":"11.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019032","HPA057273"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear membrane"],"Antibody RRID":{"HPA019032":"AB_1847363","HPA057273":"AB_2683391"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.90e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.52e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.6","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"1.2","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"4.9","Tissue RNA - cerebral cortex [nTPM]":"0.7","Tissue RNA - cervix [nTPM]":"0.7","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.9","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.9","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"0.9","Tissue RNA - midbrain [nTPM]":"1.3","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"1.2","Tissue RNA - pons [nTPM]":"1.1","Tissue RNA - prostate [nTPM]":"0.6","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"1.0","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.9","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"1.1","Tissue RNA - thymus [nTPM]":"2.0","Tissue RNA - thyroid gland [nTPM]":"0.5","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"2.2","Cell RNA - A-431 [nTPM]":"0.7","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"8.0","Cell RNA - AN3-CA [nTPM]":"9.0","Cell RNA - ASC diff [nTPM]":"0.8","Cell RNA - ASC TERT1 [nTPM]":"0.7","Cell RNA - BEWO [nTPM]":"17.7","Cell RNA - BJ [nTPM]":"0.4","Cell RNA - BJ hTERT+ [nTPM]":"1.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.2","Cell RNA - CACO-2 [nTPM]":"5.5","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.8","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"20.4","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.8","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"3.3","Cell RNA - HEL [nTPM]":"2.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"4.9","Cell RNA - HHSteC [nTPM]":"1.2","Cell RNA - HL-60 [nTPM]":"1.9","Cell RNA - HMC-1 [nTPM]":"1.0","Cell RNA - HSkMC [nTPM]":"1.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.5","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"1.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"3.5","Cell RNA - K-562 [nTPM]":"12.0","Cell RNA - Karpas-707 [nTPM]":"1.4","Cell RNA - LHCN-M2 [nTPM]":"0.7","Cell RNA - MCF7 [nTPM]":"0.6","Cell RNA - MOLT-4 [nTPM]":"3.3","Cell RNA - NB-4 [nTPM]":"1.4","Cell RNA - NTERA-2 [nTPM]":"11.9","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"1.1","Cell RNA - REH [nTPM]":"3.2","Cell RNA - RH-30 [nTPM]":"2.5","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.4","Cell RNA - RT4 [nTPM]":"0.8","Cell RNA - SCLC-21H [nTPM]":"2.2","Cell RNA - SH-SY5Y [nTPM]":"3.5","Cell RNA - SiHa [nTPM]":"0.4","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"1.6","Cell RNA - SuSa [nTPM]":"7.9","Cell RNA - T-47d [nTPM]":"1.0","Cell RNA - THP-1 [nTPM]":"1.5","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.7","Cell RNA - U-2 OS [nTPM]":"1.6","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.6","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"3.2","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.5","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.6","Brain RNA - basal ganglia [nTPM]":"1.2","Brain RNA - cerebellum [nTPM]":"4.9","Brain RNA - cerebral cortex [nTPM]":"0.7","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.9","Brain RNA - medulla oblongata [nTPM]":"0.9","Brain RNA - midbrain [nTPM]":"1.3","Brain RNA - pons [nTPM]":"1.1","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"1.1","Brain RNA - white matter [nTPM]":"2.2","Single Cell Type RNA - Adipocytes [nTPM]":"6.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.2","Single Cell Type RNA - Astrocytes [nTPM]":"54.5","Single Cell Type RNA - B-cells [nTPM]":"2.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"2.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"2.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"21.0","Single Cell Type RNA - dendritic cells [nTPM]":"3.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"34.2","Single Cell Type RNA - Endothelial cells [nTPM]":"4.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.8","Single Cell Type RNA - Erythroid cells [nTPM]":"2.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"79.9","Single Cell Type RNA - Fibroblasts [nTPM]":"15.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"13.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.7","Single Cell Type RNA - Hepatocytes [nTPM]":"2.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.9","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.7","Single Cell Type RNA - Leydig cells [nTPM]":"25.7","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"0.4","Single Cell Type RNA - Muller glia cells [nTPM]":"16.1","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"44.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"45.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"20.7","Single Cell Type RNA - Plasma cells [nTPM]":"7.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"27.9","Single Cell Type RNA - T-cells [nTPM]":"2.6","Single Cell Type RNA - Theca cells [nTPM]":"43.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"TET2","Gene synonym":["FLJ20032","KIAA1546"],"Ensembl":"ENSG00000168769","Gene description":"Tet methylcytosine dioxygenase 2","Uniprot":["Q6N021"],"Chromosome":"4","Position":"105145875-105279816","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle"],"Molecular function":["Chromatin regulator","Dioxygenase","DNA-binding","Oxidoreductase"],"Disease involvement":["Cancer-related genes","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"112.6","Oligodendrocytes":"128.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"55.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"55.5"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043135"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA043135":"AB_10794177"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.3","Tissue RNA - adrenal gland [nTPM]":"3.1","Tissue RNA - amygdala [nTPM]":"2.9","Tissue RNA - appendix [nTPM]":"10.1","Tissue RNA - basal ganglia [nTPM]":"4.4","Tissue RNA - bone marrow [nTPM]":"22.4","Tissue RNA - breast [nTPM]":"5.4","Tissue RNA - cerebellum [nTPM]":"2.5","Tissue RNA - cerebral cortex [nTPM]":"2.7","Tissue RNA - cervix [nTPM]":"6.3","Tissue RNA - choroid plexus [nTPM]":"5.8","Tissue RNA - colon [nTPM]":"5.2","Tissue RNA - duodenum [nTPM]":"6.1","Tissue RNA - endometrium 1 [nTPM]":"7.2","Tissue RNA - epididymis [nTPM]":"6.0","Tissue RNA - esophagus [nTPM]":"7.7","Tissue RNA - fallopian tube [nTPM]":"4.9","Tissue RNA - gallbladder [nTPM]":"5.0","Tissue RNA - heart muscle [nTPM]":"3.3","Tissue RNA - hippocampal formation [nTPM]":"2.1","Tissue RNA - hypothalamus [nTPM]":"4.6","Tissue RNA - kidney [nTPM]":"4.1","Tissue RNA - liver [nTPM]":"4.2","Tissue RNA - lung [nTPM]":"5.4","Tissue RNA - lymph node [nTPM]":"5.6","Tissue RNA - medulla oblongata [nTPM]":"5.3","Tissue RNA - midbrain [nTPM]":"4.4","Tissue RNA - ovary [nTPM]":"4.3","Tissue RNA - pancreas [nTPM]":"3.7","Tissue RNA - parathyroid gland [nTPM]":"4.6","Tissue RNA - pituitary gland [nTPM]":"1.8","Tissue RNA - placenta [nTPM]":"10.2","Tissue RNA - pons [nTPM]":"5.3","Tissue RNA - prostate [nTPM]":"4.4","Tissue RNA - rectum [nTPM]":"5.9","Tissue RNA - retina [nTPM]":"6.6","Tissue RNA - salivary gland [nTPM]":"4.7","Tissue RNA - seminal vesicle [nTPM]":"3.3","Tissue RNA - skeletal muscle [nTPM]":"2.8","Tissue RNA - skin 1 [nTPM]":"11.0","Tissue RNA - small intestine [nTPM]":"6.0","Tissue RNA - smooth muscle [nTPM]":"5.7","Tissue RNA - spinal cord [nTPM]":"2.9","Tissue RNA - spleen [nTPM]":"7.2","Tissue RNA - stomach 1 [nTPM]":"5.3","Tissue RNA - testis [nTPM]":"1.3","Tissue RNA - thalamus [nTPM]":"4.1","Tissue RNA - thymus [nTPM]":"5.4","Tissue RNA - thyroid gland [nTPM]":"4.2","Tissue RNA - tongue [nTPM]":"5.2","Tissue RNA - tonsil [nTPM]":"7.0","Tissue RNA - urinary bladder [nTPM]":"5.5","Tissue RNA - vagina [nTPM]":"4.5","Tissue RNA - white matter [nTPM]":"5.6","Cell RNA - A-431 [nTPM]":"5.1","Cell RNA - A549 [nTPM]":"3.1","Cell RNA - AF22 [nTPM]":"10.9","Cell RNA - AN3-CA [nTPM]":"11.1","Cell RNA - ASC diff [nTPM]":"2.1","Cell RNA - ASC TERT1 [nTPM]":"3.7","Cell RNA - BEWO [nTPM]":"4.2","Cell RNA - BJ [nTPM]":"3.1","Cell RNA - BJ hTERT+ [nTPM]":"4.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.7","Cell RNA - CACO-2 [nTPM]":"3.1","Cell RNA - CAPAN-2 [nTPM]":"6.4","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"4.0","Cell RNA - fHDF\/TERT166 [nTPM]":"4.0","Cell RNA - GAMG [nTPM]":"2.1","Cell RNA - HaCaT [nTPM]":"4.9","Cell RNA - HAP1 [nTPM]":"9.3","Cell RNA - HBEC3-KT [nTPM]":"6.1","Cell RNA - HBF TERT88 [nTPM]":"5.3","Cell RNA - HDLM-2 [nTPM]":"6.7","Cell RNA - HEK 293 [nTPM]":"2.9","Cell RNA - HEL [nTPM]":"7.0","Cell RNA - HeLa [nTPM]":"6.5","Cell RNA - Hep G2 [nTPM]":"1.6","Cell RNA - HHSteC [nTPM]":"4.9","Cell RNA - HL-60 [nTPM]":"15.5","Cell RNA - HMC-1 [nTPM]":"11.8","Cell RNA - HSkMC [nTPM]":"3.8","Cell RNA - hTCEpi [nTPM]":"7.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.5","Cell RNA - hTERT-HME1 [nTPM]":"5.6","Cell RNA - hTERT-RPE1 [nTPM]":"8.6","Cell RNA - HUVEC TERT2 [nTPM]":"6.4","Cell RNA - JURKAT [nTPM]":"4.1","Cell RNA - K-562 [nTPM]":"7.7","Cell RNA - Karpas-707 [nTPM]":"13.6","Cell RNA - LHCN-M2 [nTPM]":"4.4","Cell RNA - MCF7 [nTPM]":"3.1","Cell RNA - MOLT-4 [nTPM]":"2.5","Cell RNA - NB-4 [nTPM]":"4.7","Cell RNA - NTERA-2 [nTPM]":"2.5","Cell RNA - OE19 [nTPM]":"6.2","Cell RNA - PC-3 [nTPM]":"2.2","Cell RNA - REH [nTPM]":"8.4","Cell RNA - RH-30 [nTPM]":"4.7","Cell RNA - RPMI-8226 [nTPM]":"1.0","Cell RNA - RPTEC TERT1 [nTPM]":"4.7","Cell RNA - RT4 [nTPM]":"9.4","Cell RNA - SCLC-21H [nTPM]":"7.5","Cell RNA - SH-SY5Y [nTPM]":"5.9","Cell RNA - SiHa [nTPM]":"4.2","Cell RNA - SK-BR-3 [nTPM]":"9.1","Cell RNA - SK-MEL-30 [nTPM]":"0.8","Cell RNA - SuSa [nTPM]":"5.9","Cell RNA - T-47d [nTPM]":"4.5","Cell RNA - THP-1 [nTPM]":"11.8","Cell RNA - TIME [nTPM]":"9.1","Cell RNA - U-138 MG [nTPM]":"7.8","Cell RNA - U-2 OS [nTPM]":"6.7","Cell RNA - U-2197 [nTPM]":"2.1","Cell RNA - U-251 MG [nTPM]":"5.3","Cell RNA - U-266\/70 [nTPM]":"9.5","Cell RNA - U-266\/84 [nTPM]":"6.8","Cell RNA - U-698 [nTPM]":"6.8","Cell RNA - U-87 MG [nTPM]":"4.8","Cell RNA - U-937 [nTPM]":"3.8","Cell RNA - WM-115 [nTPM]":"7.2","Blood RNA - basophil [nTPM]":"30.1","Blood RNA - classical monocyte [nTPM]":"13.6","Blood RNA - eosinophil [nTPM]":"14.7","Blood RNA - gdT-cell [nTPM]":"3.9","Blood RNA - intermediate monocyte [nTPM]":"10.4","Blood RNA - MAIT T-cell [nTPM]":"1.6","Blood RNA - memory B-cell [nTPM]":"5.3","Blood RNA - memory CD4 T-cell [nTPM]":"2.3","Blood RNA - memory CD8 T-cell [nTPM]":"2.2","Blood RNA - myeloid DC [nTPM]":"10.2","Blood RNA - naive B-cell [nTPM]":"6.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.9","Blood RNA - naive CD8 T-cell [nTPM]":"2.9","Blood RNA - neutrophil [nTPM]":"55.5","Blood RNA - NK-cell [nTPM]":"5.9","Blood RNA - non-classical monocyte [nTPM]":"13.6","Blood RNA - plasmacytoid DC [nTPM]":"8.9","Blood RNA - T-reg [nTPM]":"3.1","Blood RNA - total PBMC [nTPM]":"3.3","Brain RNA - amygdala [nTPM]":"2.9","Brain RNA - basal ganglia [nTPM]":"4.4","Brain RNA - cerebellum [nTPM]":"2.5","Brain RNA - cerebral cortex [nTPM]":"2.7","Brain RNA - hippocampal formation [nTPM]":"2.1","Brain RNA - hypothalamus [nTPM]":"4.6","Brain RNA - medulla oblongata [nTPM]":"5.3","Brain RNA - midbrain [nTPM]":"4.4","Brain RNA - pons [nTPM]":"5.3","Brain RNA - spinal cord [nTPM]":"2.9","Brain RNA - thalamus [nTPM]":"4.1","Brain RNA - white matter [nTPM]":"5.6","Single Cell Type RNA - Adipocytes [nTPM]":"24.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.1","Single Cell Type RNA - Astrocytes [nTPM]":"58.8","Single Cell Type RNA - B-cells [nTPM]":"28.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Bipolar cells [nTPM]":"22.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"27.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"23.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.1","Single Cell Type RNA - dendritic cells [nTPM]":"34.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"19.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"38.3","Single Cell Type RNA - Endothelial cells [nTPM]":"20.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"23.3","Single Cell Type RNA - Erythroid cells [nTPM]":"10.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"48.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.7","Single Cell Type RNA - Fibroblasts [nTPM]":"18.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"33.2","Single Cell Type RNA - granulocytes [nTPM]":"27.8","Single Cell Type RNA - Granulosa cells [nTPM]":"15.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"8.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.5","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"89.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.8","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"48.8","Single Cell Type RNA - Langerhans cells [nTPM]":"93.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"98.3","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"90.9","Single Cell Type RNA - monocytes [nTPM]":"48.1","Single Cell Type RNA - Muller glia cells [nTPM]":"5.8","Single Cell Type RNA - NK-cells [nTPM]":"34.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"112.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"128.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.2","Single Cell Type RNA - Paneth cells [nTPM]":"18.7","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"22.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"16.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.3","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"47.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"35.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"34.2","Single Cell Type RNA - T-cells [nTPM]":"18.9","Single Cell Type RNA - Theca cells [nTPM]":"24.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.0","Single Cell Type RNA - Urothelial cells [nTPM]":"27.5"},{"Gene":"TET3","Gene synonym":["hCG_40738","MGC22014"],"Ensembl":"ENSG00000187605","Gene description":"Tet methylcytosine dioxygenase 3","Uniprot":["O43151"],"Chromosome":"2","Position":"73984910-74108176","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Chromatin regulator","Developmental protein","Dioxygenase","DNA-binding","Oxidoreductase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"19.7","skin 1":"16.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"88.5","Oligodendrocytes":"86.7","Suprabasal keratinocytes":"68.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050845"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"HPA050845":"AB_2681256"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.58e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Tissue RNA - adipose tissue [nTPM]":"2.2","Tissue RNA - adrenal gland [nTPM]":"1.6","Tissue RNA - amygdala [nTPM]":"3.7","Tissue RNA - appendix [nTPM]":"5.2","Tissue RNA - basal ganglia [nTPM]":"2.4","Tissue RNA - bone marrow [nTPM]":"19.7","Tissue RNA - breast [nTPM]":"3.0","Tissue RNA - cerebellum [nTPM]":"6.3","Tissue RNA - cerebral cortex [nTPM]":"13.7","Tissue RNA - cervix [nTPM]":"2.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"4.1","Tissue RNA - duodenum [nTPM]":"5.4","Tissue RNA - endometrium 1 [nTPM]":"2.0","Tissue RNA - epididymis [nTPM]":"1.4","Tissue RNA - esophagus [nTPM]":"7.6","Tissue RNA - fallopian tube [nTPM]":"1.9","Tissue RNA - gallbladder [nTPM]":"2.5","Tissue RNA - heart muscle [nTPM]":"1.2","Tissue RNA - hippocampal formation [nTPM]":"9.3","Tissue RNA - hypothalamus [nTPM]":"1.7","Tissue RNA - kidney [nTPM]":"1.6","Tissue RNA - liver [nTPM]":"3.9","Tissue RNA - lung [nTPM]":"4.1","Tissue RNA - lymph node [nTPM]":"3.7","Tissue RNA - medulla oblongata [nTPM]":"2.0","Tissue RNA - midbrain [nTPM]":"1.5","Tissue RNA - ovary [nTPM]":"1.5","Tissue RNA - pancreas [nTPM]":"2.6","Tissue RNA - parathyroid gland [nTPM]":"2.0","Tissue RNA - pituitary gland [nTPM]":"1.5","Tissue RNA - placenta [nTPM]":"4.6","Tissue RNA - pons [nTPM]":"2.2","Tissue RNA - prostate [nTPM]":"2.5","Tissue RNA - rectum [nTPM]":"4.3","Tissue RNA - retina [nTPM]":"3.6","Tissue RNA - salivary gland [nTPM]":"4.2","Tissue RNA - seminal vesicle [nTPM]":"1.1","Tissue RNA - skeletal muscle [nTPM]":"1.2","Tissue RNA - skin 1 [nTPM]":"16.2","Tissue RNA - small intestine [nTPM]":"6.0","Tissue RNA - smooth muscle [nTPM]":"2.1","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"3.8","Tissue RNA - stomach 1 [nTPM]":"4.3","Tissue RNA - testis [nTPM]":"1.6","Tissue RNA - thalamus [nTPM]":"2.7","Tissue RNA - thymus [nTPM]":"5.8","Tissue RNA - thyroid gland [nTPM]":"2.3","Tissue RNA - tongue [nTPM]":"1.3","Tissue RNA - tonsil [nTPM]":"4.1","Tissue RNA - urinary bladder [nTPM]":"3.4","Tissue RNA - vagina [nTPM]":"4.0","Tissue RNA - white matter [nTPM]":"5.8","Cell RNA - A-431 [nTPM]":"9.0","Cell RNA - A549 [nTPM]":"8.0","Cell RNA - AF22 [nTPM]":"14.5","Cell RNA - AN3-CA [nTPM]":"8.9","Cell RNA - ASC diff [nTPM]":"1.2","Cell RNA - ASC TERT1 [nTPM]":"1.3","Cell RNA - BEWO [nTPM]":"26.4","Cell RNA - BJ [nTPM]":"1.8","Cell RNA - BJ hTERT+ [nTPM]":"2.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.7","Cell RNA - CACO-2 [nTPM]":"16.6","Cell RNA - CAPAN-2 [nTPM]":"8.1","Cell RNA - Daudi [nTPM]":"14.9","Cell RNA - EFO-21 [nTPM]":"3.5","Cell RNA - fHDF\/TERT166 [nTPM]":"2.4","Cell RNA - GAMG [nTPM]":"1.6","Cell RNA - HaCaT [nTPM]":"9.4","Cell RNA - HAP1 [nTPM]":"13.0","Cell RNA - HBEC3-KT [nTPM]":"5.2","Cell RNA - HBF TERT88 [nTPM]":"3.6","Cell RNA - HDLM-2 [nTPM]":"6.7","Cell RNA - HEK 293 [nTPM]":"5.2","Cell RNA - HEL [nTPM]":"19.2","Cell RNA - HeLa [nTPM]":"7.0","Cell RNA - Hep G2 [nTPM]":"5.6","Cell RNA - HHSteC [nTPM]":"5.1","Cell RNA - HL-60 [nTPM]":"20.2","Cell RNA - HMC-1 [nTPM]":"11.3","Cell RNA - HSkMC [nTPM]":"2.0","Cell RNA - hTCEpi [nTPM]":"13.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.2","Cell RNA - hTERT-HME1 [nTPM]":"9.9","Cell RNA - hTERT-RPE1 [nTPM]":"4.3","Cell RNA - HUVEC TERT2 [nTPM]":"5.3","Cell RNA - JURKAT [nTPM]":"10.3","Cell RNA - K-562 [nTPM]":"13.4","Cell RNA - Karpas-707 [nTPM]":"4.8","Cell RNA - LHCN-M2 [nTPM]":"2.0","Cell RNA - MCF7 [nTPM]":"14.6","Cell RNA - MOLT-4 [nTPM]":"10.0","Cell RNA - NB-4 [nTPM]":"13.0","Cell RNA - NTERA-2 [nTPM]":"8.1","Cell RNA - OE19 [nTPM]":"7.7","Cell RNA - PC-3 [nTPM]":"2.7","Cell RNA - REH [nTPM]":"15.4","Cell RNA - RH-30 [nTPM]":"9.1","Cell RNA - RPMI-8226 [nTPM]":"5.2","Cell RNA - RPTEC TERT1 [nTPM]":"3.8","Cell RNA - RT4 [nTPM]":"16.5","Cell RNA - SCLC-21H [nTPM]":"18.1","Cell RNA - SH-SY5Y [nTPM]":"15.5","Cell RNA - SiHa [nTPM]":"4.0","Cell RNA - SK-BR-3 [nTPM]":"10.3","Cell RNA - SK-MEL-30 [nTPM]":"4.9","Cell RNA - SuSa [nTPM]":"5.7","Cell RNA - T-47d [nTPM]":"6.6","Cell RNA - THP-1 [nTPM]":"16.1","Cell RNA - TIME [nTPM]":"6.7","Cell RNA - U-138 MG [nTPM]":"3.7","Cell RNA - U-2 OS [nTPM]":"15.4","Cell RNA - U-2197 [nTPM]":"1.8","Cell RNA - U-251 MG [nTPM]":"6.8","Cell RNA - U-266\/70 [nTPM]":"4.2","Cell RNA - U-266\/84 [nTPM]":"2.0","Cell RNA - U-698 [nTPM]":"12.7","Cell RNA - U-87 MG [nTPM]":"2.4","Cell RNA - U-937 [nTPM]":"13.9","Cell RNA - WM-115 [nTPM]":"4.9","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"3.7","Brain RNA - basal ganglia [nTPM]":"2.4","Brain RNA - cerebellum [nTPM]":"6.3","Brain RNA - cerebral cortex [nTPM]":"13.7","Brain RNA - hippocampal formation [nTPM]":"9.3","Brain RNA - hypothalamus [nTPM]":"1.7","Brain RNA - medulla oblongata [nTPM]":"2.0","Brain RNA - midbrain [nTPM]":"1.5","Brain RNA - pons [nTPM]":"2.2","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"2.7","Brain RNA - white matter [nTPM]":"5.8","Single Cell Type RNA - Adipocytes [nTPM]":"4.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.0","Single Cell Type RNA - Astrocytes [nTPM]":"31.3","Single Cell Type RNA - B-cells [nTPM]":"6.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"49.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"16.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"8.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.0","Single Cell Type RNA - dendritic cells [nTPM]":"7.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.5","Single Cell Type RNA - Early spermatids [nTPM]":"4.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.9","Single Cell Type RNA - Endothelial cells [nTPM]":"6.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"24.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"88.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"30.1","Single Cell Type RNA - Fibroblasts [nTPM]":"3.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"29.6","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"6.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"6.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.1","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"45.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.0","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"26.9","Single Cell Type RNA - Langerhans cells [nTPM]":"23.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"26.9","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"54.4","Single Cell Type RNA - monocytes [nTPM]":"27.1","Single Cell Type RNA - Muller glia cells [nTPM]":"1.5","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"41.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"86.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.2","Single Cell Type RNA - Paneth cells [nTPM]":"7.7","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"4.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"2.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"24.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"68.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - T-cells [nTPM]":"5.5","Single Cell Type RNA - Theca cells [nTPM]":"2.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.9","Single Cell Type RNA - Urothelial cells [nTPM]":"7.0"},{"Gene":"TEX14","Gene synonym":["CT113"],"Ensembl":"ENSG00000121101","Gene description":"Testis expressed 14, intercellular bridge forming factor","Uniprot":["Q8IWB6"],"Chromosome":"17","Position":"58556678-58692055","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Cell cycle","Cell division","Mitosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"15","RNA tissue specific nTPM":{"testis":"27.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"23.3","Spermatocytes":"56.4","Spermatogonia":"16.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"0.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"6.3","Karpas-707":"7.9","MCF7":"3.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030620","HPA077020"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles","Plasma membrane"],"Antibody RRID":{"HPA030620":"AB_10601598","HPA077020":"AB_2732327"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"1.7","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"1.1","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"0.5","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.5","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.5","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"1.1","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"27.0","Tissue RNA - thalamus [nTPM]":"0.5","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"1.7","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"6.3","Cell RNA - HEK 293 [nTPM]":"0.9","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.8","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"7.9","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"3.3","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"1.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.9","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"1.4","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.7","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"1.1","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"0.5","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.5","Brain RNA - pons [nTPM]":"0.5","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"0.5","Brain RNA - white matter [nTPM]":"0.8","Single Cell Type RNA - Adipocytes [nTPM]":"4.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.9","Single Cell Type RNA - B-cells [nTPM]":"5.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"1.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"23.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"1.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.8","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.5","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"2.3","Single Cell Type RNA - Late spermatids [nTPM]":"6.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"4.6","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.6","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"4.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.5","Single Cell Type RNA - Spermatocytes [nTPM]":"56.4","Single Cell Type RNA - Spermatogonia [nTPM]":"16.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - T-cells [nTPM]":"0.7","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"TGDS","Gene synonym":["SDR2E1","TDPGD"],"Ensembl":"ENSG00000088451","Gene description":"TDP-glucose 4,6-dehydratase","Uniprot":["O95455"],"Chromosome":"13","Position":"94574054-94596242","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Lyase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HL-60":"75.2","U-698":"97.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039927","HPA040857"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli","Cytosol"],"Antibody RRID":{"HPA039927":"AB_10795238","HPA040857":"AB_10794867"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.48e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.4","Tissue RNA - adrenal gland [nTPM]":"9.4","Tissue RNA - amygdala [nTPM]":"5.3","Tissue RNA - appendix [nTPM]":"8.2","Tissue RNA - basal ganglia [nTPM]":"5.5","Tissue RNA - bone marrow [nTPM]":"6.0","Tissue RNA - breast [nTPM]":"12.4","Tissue RNA - cerebellum [nTPM]":"5.6","Tissue RNA - cerebral cortex [nTPM]":"8.2","Tissue RNA - cervix [nTPM]":"10.4","Tissue RNA - choroid plexus [nTPM]":"6.3","Tissue RNA - colon [nTPM]":"8.0","Tissue RNA - duodenum [nTPM]":"10.2","Tissue RNA - endometrium 1 [nTPM]":"8.0","Tissue RNA - epididymis [nTPM]":"11.8","Tissue RNA - esophagus [nTPM]":"6.9","Tissue RNA - fallopian tube [nTPM]":"9.2","Tissue RNA - gallbladder [nTPM]":"6.8","Tissue RNA - heart muscle [nTPM]":"5.4","Tissue RNA - hippocampal formation [nTPM]":"4.9","Tissue RNA - hypothalamus [nTPM]":"5.6","Tissue RNA - kidney [nTPM]":"10.9","Tissue RNA - liver [nTPM]":"30.0","Tissue RNA - lung [nTPM]":"7.1","Tissue RNA - lymph node [nTPM]":"12.9","Tissue RNA - medulla oblongata [nTPM]":"5.6","Tissue RNA - midbrain [nTPM]":"5.4","Tissue RNA - ovary [nTPM]":"12.1","Tissue RNA - pancreas [nTPM]":"10.0","Tissue RNA - parathyroid gland [nTPM]":"8.1","Tissue RNA - pituitary gland [nTPM]":"8.4","Tissue RNA - placenta [nTPM]":"10.1","Tissue RNA - pons [nTPM]":"5.9","Tissue RNA - prostate [nTPM]":"7.9","Tissue RNA - rectum [nTPM]":"9.5","Tissue RNA - retina [nTPM]":"6.9","Tissue RNA - salivary gland [nTPM]":"7.7","Tissue RNA - seminal vesicle [nTPM]":"7.6","Tissue RNA - skeletal muscle [nTPM]":"4.1","Tissue RNA - skin 1 [nTPM]":"7.5","Tissue RNA - small intestine [nTPM]":"9.2","Tissue RNA - smooth muscle [nTPM]":"6.7","Tissue RNA - spinal cord [nTPM]":"5.6","Tissue RNA - spleen [nTPM]":"9.2","Tissue RNA - stomach 1 [nTPM]":"9.1","Tissue RNA - testis [nTPM]":"6.0","Tissue RNA - thalamus [nTPM]":"5.3","Tissue RNA - thymus [nTPM]":"14.1","Tissue RNA - thyroid gland [nTPM]":"13.3","Tissue RNA - tongue [nTPM]":"4.3","Tissue RNA - tonsil [nTPM]":"11.0","Tissue RNA - urinary bladder [nTPM]":"9.1","Tissue RNA - vagina [nTPM]":"6.4","Tissue RNA - white matter [nTPM]":"6.6","Cell RNA - A-431 [nTPM]":"16.7","Cell RNA - A549 [nTPM]":"7.2","Cell RNA - AF22 [nTPM]":"11.6","Cell RNA - AN3-CA [nTPM]":"10.6","Cell RNA - ASC diff [nTPM]":"17.2","Cell RNA - ASC TERT1 [nTPM]":"13.5","Cell RNA - BEWO [nTPM]":"14.1","Cell RNA - BJ [nTPM]":"15.3","Cell RNA - BJ hTERT+ [nTPM]":"14.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.4","Cell RNA - CACO-2 [nTPM]":"18.9","Cell RNA - CAPAN-2 [nTPM]":"15.9","Cell RNA - Daudi [nTPM]":"26.0","Cell RNA - EFO-21 [nTPM]":"14.8","Cell RNA - fHDF\/TERT166 [nTPM]":"10.9","Cell RNA - GAMG [nTPM]":"8.8","Cell RNA - HaCaT [nTPM]":"10.4","Cell RNA - HAP1 [nTPM]":"20.1","Cell RNA - HBEC3-KT [nTPM]":"11.9","Cell RNA - HBF TERT88 [nTPM]":"14.9","Cell RNA - HDLM-2 [nTPM]":"20.3","Cell RNA - HEK 293 [nTPM]":"7.7","Cell RNA - HEL [nTPM]":"20.7","Cell RNA - HeLa [nTPM]":"8.1","Cell RNA - Hep G2 [nTPM]":"18.1","Cell RNA - HHSteC [nTPM]":"21.0","Cell RNA - HL-60 [nTPM]":"75.2","Cell RNA - HMC-1 [nTPM]":"13.8","Cell RNA - HSkMC [nTPM]":"14.9","Cell RNA - hTCEpi [nTPM]":"9.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.0","Cell RNA - hTERT-HME1 [nTPM]":"22.8","Cell RNA - hTERT-RPE1 [nTPM]":"11.1","Cell RNA - HUVEC TERT2 [nTPM]":"13.2","Cell RNA - JURKAT [nTPM]":"18.9","Cell RNA - K-562 [nTPM]":"21.3","Cell RNA - Karpas-707 [nTPM]":"8.9","Cell RNA - LHCN-M2 [nTPM]":"13.3","Cell RNA - MCF7 [nTPM]":"10.8","Cell RNA - MOLT-4 [nTPM]":"20.6","Cell RNA - NB-4 [nTPM]":"38.4","Cell RNA - NTERA-2 [nTPM]":"15.2","Cell RNA - OE19 [nTPM]":"26.8","Cell RNA - PC-3 [nTPM]":"8.3","Cell RNA - REH [nTPM]":"17.1","Cell RNA - RH-30 [nTPM]":"11.4","Cell RNA - RPMI-8226 [nTPM]":"15.9","Cell RNA - RPTEC TERT1 [nTPM]":"18.3","Cell RNA - RT4 [nTPM]":"7.4","Cell RNA - SCLC-21H [nTPM]":"15.9","Cell RNA - SH-SY5Y [nTPM]":"8.9","Cell RNA - SiHa [nTPM]":"11.6","Cell RNA - SK-BR-3 [nTPM]":"24.2","Cell RNA - SK-MEL-30 [nTPM]":"43.5","Cell RNA - SuSa [nTPM]":"19.1","Cell RNA - T-47d [nTPM]":"10.2","Cell RNA - THP-1 [nTPM]":"39.8","Cell RNA - TIME [nTPM]":"12.2","Cell RNA - U-138 MG [nTPM]":"5.6","Cell RNA - U-2 OS [nTPM]":"14.5","Cell RNA - U-2197 [nTPM]":"8.6","Cell RNA - U-251 MG [nTPM]":"12.6","Cell RNA - U-266\/70 [nTPM]":"20.0","Cell RNA - U-266\/84 [nTPM]":"11.4","Cell RNA - U-698 [nTPM]":"97.5","Cell RNA - U-87 MG [nTPM]":"14.9","Cell RNA - U-937 [nTPM]":"26.5","Cell RNA - WM-115 [nTPM]":"15.5","Blood RNA - basophil [nTPM]":"14.7","Blood RNA - classical monocyte [nTPM]":"5.5","Blood RNA - eosinophil [nTPM]":"10.8","Blood RNA - gdT-cell [nTPM]":"9.6","Blood RNA - intermediate monocyte [nTPM]":"6.6","Blood RNA - MAIT T-cell [nTPM]":"14.9","Blood RNA - memory B-cell [nTPM]":"9.5","Blood RNA - memory CD4 T-cell [nTPM]":"11.6","Blood RNA - memory CD8 T-cell [nTPM]":"10.7","Blood RNA - myeloid DC [nTPM]":"8.7","Blood RNA - naive B-cell [nTPM]":"7.1","Blood RNA - naive CD4 T-cell [nTPM]":"16.8","Blood RNA - naive CD8 T-cell [nTPM]":"12.5","Blood RNA - neutrophil [nTPM]":"1.6","Blood RNA - NK-cell [nTPM]":"12.1","Blood RNA - non-classical monocyte [nTPM]":"8.3","Blood RNA - plasmacytoid DC [nTPM]":"7.6","Blood RNA - T-reg [nTPM]":"13.8","Blood RNA - total PBMC [nTPM]":"6.9","Brain RNA - amygdala [nTPM]":"5.3","Brain RNA - basal ganglia [nTPM]":"5.5","Brain RNA - cerebellum [nTPM]":"5.6","Brain RNA - cerebral cortex [nTPM]":"8.2","Brain RNA - hippocampal formation [nTPM]":"4.9","Brain RNA - hypothalamus [nTPM]":"5.6","Brain RNA - medulla oblongata [nTPM]":"5.6","Brain RNA - midbrain [nTPM]":"5.4","Brain RNA - pons [nTPM]":"5.9","Brain RNA - spinal cord [nTPM]":"5.6","Brain RNA - thalamus [nTPM]":"5.3","Brain RNA - white matter [nTPM]":"6.6","Single Cell Type RNA - Adipocytes [nTPM]":"7.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.8","Single Cell Type RNA - Astrocytes [nTPM]":"8.1","Single Cell Type RNA - B-cells [nTPM]":"12.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"4.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"11.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.7","Single Cell Type RNA - dendritic cells [nTPM]":"12.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"11.9","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.9","Single Cell Type RNA - Endothelial cells [nTPM]":"7.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"3.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.7","Single Cell Type RNA - Fibroblasts [nTPM]":"12.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.0","Single Cell Type RNA - granulocytes [nTPM]":"11.4","Single Cell Type RNA - Granulosa cells [nTPM]":"7.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"21.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.2","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.7","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"8.8","Single Cell Type RNA - Langerhans cells [nTPM]":"7.2","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"14.3","Single Cell Type RNA - Macrophages [nTPM]":"7.5","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"11.1","Single Cell Type RNA - Muller glia cells [nTPM]":"7.0","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.9","Single Cell Type RNA - Paneth cells [nTPM]":"6.6","Single Cell Type RNA - Peritubular cells [nTPM]":"8.2","Single Cell Type RNA - Plasma cells [nTPM]":"10.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.7","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.1","Single Cell Type RNA - Spermatocytes [nTPM]":"11.9","Single Cell Type RNA - Spermatogonia [nTPM]":"12.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.4","Single Cell Type RNA - T-cells [nTPM]":"11.0","Single Cell Type RNA - Theca cells [nTPM]":"9.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.1","Single Cell Type RNA - Urothelial cells [nTPM]":"9.7"},{"Gene":"TGFBR1","Gene synonym":["ACVRLK4","ALK-5","ALK5","ESS1","MSSE","TBR-i","TBRI"],"Ensembl":"ENSG00000106799","Gene description":"Transforming growth factor beta receptor 1","Uniprot":["P36897"],"Chromosome":"9","Position":"99104038-99154192","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Differentiation","Growth regulation"],"Molecular function":["Kinase","Receptor","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Aortic aneurysm","Craniosynostosis","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"128.4","Late spermatids":"101.7","Microglial cells":"116.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RH-30":"253.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002441","CAB031481","HPA056473"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 65: Plasmacytoid DCs - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB002441":"AB_564029","CAB031481":"AB_2202455","HPA056473":"AB_2683144"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.9","Tissue RNA - adrenal gland [nTPM]":"9.9","Tissue RNA - amygdala [nTPM]":"9.8","Tissue RNA - appendix [nTPM]":"18.2","Tissue RNA - basal ganglia [nTPM]":"9.3","Tissue RNA - bone marrow [nTPM]":"33.7","Tissue RNA - breast [nTPM]":"15.4","Tissue RNA - cerebellum [nTPM]":"13.2","Tissue RNA - cerebral cortex [nTPM]":"8.9","Tissue RNA - cervix [nTPM]":"19.4","Tissue RNA - choroid plexus [nTPM]":"11.8","Tissue RNA - colon [nTPM]":"18.8","Tissue RNA - duodenum [nTPM]":"11.7","Tissue RNA - endometrium 1 [nTPM]":"20.6","Tissue RNA - epididymis [nTPM]":"8.8","Tissue RNA - esophagus [nTPM]":"15.0","Tissue RNA - fallopian tube [nTPM]":"8.5","Tissue RNA - gallbladder [nTPM]":"21.7","Tissue RNA - heart muscle [nTPM]":"8.2","Tissue RNA - hippocampal formation [nTPM]":"6.8","Tissue RNA - hypothalamus [nTPM]":"11.3","Tissue RNA - kidney [nTPM]":"22.6","Tissue RNA - liver [nTPM]":"14.8","Tissue RNA - lung [nTPM]":"16.3","Tissue RNA - lymph node [nTPM]":"13.8","Tissue RNA - medulla oblongata [nTPM]":"18.4","Tissue RNA - midbrain [nTPM]":"14.5","Tissue RNA - ovary [nTPM]":"13.0","Tissue RNA - pancreas [nTPM]":"8.3","Tissue RNA - parathyroid gland [nTPM]":"8.5","Tissue RNA - pituitary gland [nTPM]":"7.6","Tissue RNA - placenta [nTPM]":"48.8","Tissue RNA - pons [nTPM]":"20.0","Tissue RNA - prostate [nTPM]":"17.1","Tissue RNA - rectum [nTPM]":"13.4","Tissue RNA - retina [nTPM]":"4.7","Tissue RNA - salivary gland [nTPM]":"8.3","Tissue RNA - seminal vesicle [nTPM]":"16.8","Tissue RNA - skeletal muscle [nTPM]":"8.7","Tissue RNA - skin 1 [nTPM]":"6.2","Tissue RNA - small intestine [nTPM]":"9.3","Tissue RNA - smooth muscle [nTPM]":"33.0","Tissue RNA - spinal cord [nTPM]":"18.0","Tissue RNA - spleen [nTPM]":"16.5","Tissue RNA - stomach 1 [nTPM]":"18.4","Tissue RNA - testis [nTPM]":"18.3","Tissue RNA - thalamus [nTPM]":"17.5","Tissue RNA - thymus [nTPM]":"11.2","Tissue RNA - thyroid gland [nTPM]":"11.2","Tissue RNA - tongue [nTPM]":"13.2","Tissue RNA - tonsil [nTPM]":"13.6","Tissue RNA - urinary bladder [nTPM]":"22.5","Tissue RNA - vagina [nTPM]":"8.4","Tissue RNA - white matter [nTPM]":"27.9","Cell RNA - A-431 [nTPM]":"13.7","Cell RNA - A549 [nTPM]":"19.5","Cell RNA - AF22 [nTPM]":"115.5","Cell RNA - AN3-CA [nTPM]":"36.1","Cell RNA - ASC diff [nTPM]":"26.2","Cell RNA - ASC TERT1 [nTPM]":"19.3","Cell RNA - BEWO [nTPM]":"17.4","Cell RNA - BJ [nTPM]":"44.1","Cell RNA - BJ hTERT+ [nTPM]":"47.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"40.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"44.9","Cell RNA - CACO-2 [nTPM]":"19.9","Cell RNA - CAPAN-2 [nTPM]":"9.3","Cell RNA - Daudi [nTPM]":"29.7","Cell RNA - EFO-21 [nTPM]":"13.4","Cell RNA - fHDF\/TERT166 [nTPM]":"34.6","Cell RNA - GAMG [nTPM]":"32.1","Cell RNA - HaCaT [nTPM]":"30.4","Cell RNA - HAP1 [nTPM]":"39.6","Cell RNA - HBEC3-KT [nTPM]":"34.1","Cell RNA - HBF TERT88 [nTPM]":"54.0","Cell RNA - HDLM-2 [nTPM]":"77.1","Cell RNA - HEK 293 [nTPM]":"12.3","Cell RNA - HEL [nTPM]":"43.9","Cell RNA - HeLa [nTPM]":"20.7","Cell RNA - Hep G2 [nTPM]":"17.8","Cell RNA - HHSteC [nTPM]":"43.2","Cell RNA - HL-60 [nTPM]":"27.2","Cell RNA - HMC-1 [nTPM]":"102.8","Cell RNA - HSkMC [nTPM]":"40.2","Cell RNA - hTCEpi [nTPM]":"35.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"62.8","Cell RNA - hTERT-HME1 [nTPM]":"29.5","Cell RNA - hTERT-RPE1 [nTPM]":"25.2","Cell RNA - HUVEC TERT2 [nTPM]":"7.4","Cell RNA - JURKAT [nTPM]":"10.9","Cell RNA - K-562 [nTPM]":"62.4","Cell RNA - Karpas-707 [nTPM]":"12.1","Cell RNA - LHCN-M2 [nTPM]":"55.4","Cell RNA - MCF7 [nTPM]":"20.3","Cell RNA - MOLT-4 [nTPM]":"4.0","Cell RNA - NB-4 [nTPM]":"31.0","Cell RNA - NTERA-2 [nTPM]":"24.7","Cell RNA - OE19 [nTPM]":"12.2","Cell RNA - PC-3 [nTPM]":"11.5","Cell RNA - REH [nTPM]":"11.0","Cell RNA - RH-30 [nTPM]":"253.1","Cell RNA - RPMI-8226 [nTPM]":"12.5","Cell RNA - RPTEC TERT1 [nTPM]":"9.9","Cell RNA - RT4 [nTPM]":"3.8","Cell RNA - SCLC-21H [nTPM]":"31.1","Cell RNA - SH-SY5Y [nTPM]":"36.2","Cell RNA - SiHa [nTPM]":"34.3","Cell RNA - SK-BR-3 [nTPM]":"150.2","Cell RNA - SK-MEL-30 [nTPM]":"46.4","Cell RNA - SuSa [nTPM]":"47.3","Cell RNA - T-47d [nTPM]":"28.1","Cell RNA - THP-1 [nTPM]":"36.6","Cell RNA - TIME [nTPM]":"13.6","Cell RNA - U-138 MG [nTPM]":"29.8","Cell RNA - U-2 OS [nTPM]":"25.5","Cell RNA - U-2197 [nTPM]":"129.3","Cell RNA - U-251 MG [nTPM]":"27.3","Cell RNA - U-266\/70 [nTPM]":"12.1","Cell RNA - U-266\/84 [nTPM]":"13.4","Cell RNA - U-698 [nTPM]":"20.0","Cell RNA - U-87 MG [nTPM]":"62.5","Cell RNA - U-937 [nTPM]":"45.9","Cell RNA - WM-115 [nTPM]":"26.2","Blood RNA - basophil [nTPM]":"16.2","Blood RNA - classical monocyte [nTPM]":"2.4","Blood RNA - eosinophil [nTPM]":"9.5","Blood RNA - gdT-cell [nTPM]":"7.8","Blood RNA - intermediate monocyte [nTPM]":"1.6","Blood RNA - MAIT T-cell [nTPM]":"6.7","Blood RNA - memory B-cell [nTPM]":"1.6","Blood RNA - memory CD4 T-cell [nTPM]":"3.3","Blood RNA - memory CD8 T-cell [nTPM]":"5.8","Blood RNA - myeloid DC [nTPM]":"2.0","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"3.2","Blood RNA - naive CD8 T-cell [nTPM]":"6.2","Blood RNA - neutrophil [nTPM]":"4.9","Blood RNA - NK-cell [nTPM]":"4.3","Blood RNA - non-classical monocyte [nTPM]":"2.0","Blood RNA - plasmacytoid DC [nTPM]":"1.4","Blood RNA - T-reg [nTPM]":"2.4","Blood RNA - total PBMC [nTPM]":"2.2","Brain RNA - amygdala [nTPM]":"9.8","Brain RNA - basal ganglia [nTPM]":"9.3","Brain RNA - cerebellum [nTPM]":"13.2","Brain RNA - cerebral cortex [nTPM]":"8.9","Brain RNA - hippocampal formation [nTPM]":"6.8","Brain RNA - hypothalamus [nTPM]":"11.3","Brain RNA - medulla oblongata [nTPM]":"18.4","Brain RNA - midbrain [nTPM]":"14.5","Brain RNA - pons [nTPM]":"20.0","Brain RNA - spinal cord [nTPM]":"18.0","Brain RNA - thalamus [nTPM]":"17.5","Brain RNA - white matter [nTPM]":"27.9","Single Cell Type RNA - Adipocytes [nTPM]":"13.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.8","Single Cell Type RNA - Astrocytes [nTPM]":"18.9","Single Cell Type RNA - B-cells [nTPM]":"18.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"23.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"19.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"44.3","Single Cell Type RNA - Bipolar cells [nTPM]":"8.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"12.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"60.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.0","Single Cell Type RNA - dendritic cells [nTPM]":"37.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"18.8","Single Cell Type RNA - Early spermatids [nTPM]":"128.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.7","Single Cell Type RNA - Endothelial cells [nTPM]":"17.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"31.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.7","Single Cell Type RNA - Fibroblasts [nTPM]":"36.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.3","Single Cell Type RNA - granulocytes [nTPM]":"29.9","Single Cell Type RNA - Granulosa cells [nTPM]":"19.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"12.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"49.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.3","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"32.4","Single Cell Type RNA - Langerhans cells [nTPM]":"52.5","Single Cell Type RNA - Late spermatids [nTPM]":"101.7","Single Cell Type RNA - Leydig cells [nTPM]":"9.6","Single Cell Type RNA - Macrophages [nTPM]":"39.7","Single Cell Type RNA - Melanocytes [nTPM]":"35.6","Single Cell Type RNA - Microglial cells [nTPM]":"116.2","Single Cell Type RNA - monocytes [nTPM]":"24.3","Single Cell Type RNA - Muller glia cells [nTPM]":"3.1","Single Cell Type RNA - NK-cells [nTPM]":"35.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"45.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"33.8","Single Cell Type RNA - Paneth cells [nTPM]":"4.2","Single Cell Type RNA - Peritubular cells [nTPM]":"13.5","Single Cell Type RNA - Plasma cells [nTPM]":"11.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.0","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.9","Single Cell Type RNA - Spermatocytes [nTPM]":"11.0","Single Cell Type RNA - Spermatogonia [nTPM]":"12.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"19.4","Single Cell Type RNA - T-cells [nTPM]":"25.4","Single Cell Type RNA - Theca cells [nTPM]":"7.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.3","Single Cell Type RNA - Urothelial cells [nTPM]":"11.5"},{"Gene":"TGM1","Gene synonym":["ICR2","LI","LI1","TGASE","TGK"],"Ensembl":"ENSG00000092295","Gene description":"Transglutaminase 1","Uniprot":["P22735"],"Chromosome":"14","Position":"24249114-24264432","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Keratinization"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant","Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"esophagus":"713.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"12.8","Basal respiratory cells":"63.6","Club cells":"18.8","Distal tubular cells":"29.4","Squamous epithelial cells":"34.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"cervical cancer":"30.8","head and neck cancer":"78.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"17.5","HaCaT":"24.2","HeLa":"16.2","MCF7":"17.5","SK-BR-3":"21.7"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015159","HPA040171","HPA070372"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"530000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB015159":"AB_2202870","HPA040171":"AB_2676869","HPA070372":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Tissue RNA - adipose tissue [nTPM]":"25.7","Tissue RNA - adrenal gland [nTPM]":"1.3","Tissue RNA - amygdala [nTPM]":"0.6","Tissue RNA - appendix [nTPM]":"0.9","Tissue RNA - basal ganglia [nTPM]":"0.8","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"2.2","Tissue RNA - cerebellum [nTPM]":"3.7","Tissue RNA - cerebral cortex [nTPM]":"2.0","Tissue RNA - cervix [nTPM]":"78.7","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"1.4","Tissue RNA - duodenum [nTPM]":"0.8","Tissue RNA - endometrium 1 [nTPM]":"1.0","Tissue RNA - epididymis [nTPM]":"1.6","Tissue RNA - esophagus [nTPM]":"713.5","Tissue RNA - fallopian tube [nTPM]":"4.4","Tissue RNA - gallbladder [nTPM]":"0.6","Tissue RNA - heart muscle [nTPM]":"5.1","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"2.5","Tissue RNA - liver [nTPM]":"1.7","Tissue RNA - lung [nTPM]":"5.3","Tissue RNA - lymph node [nTPM]":"1.5","Tissue RNA - medulla oblongata [nTPM]":"1.5","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"3.0","Tissue RNA - pancreas [nTPM]":"3.2","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"3.3","Tissue RNA - placenta [nTPM]":"1.2","Tissue RNA - pons [nTPM]":"1.4","Tissue RNA - prostate [nTPM]":"4.1","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"1.7","Tissue RNA - salivary gland [nTPM]":"89.7","Tissue RNA - seminal vesicle [nTPM]":"4.4","Tissue RNA - skeletal muscle [nTPM]":"1.1","Tissue RNA - skin 1 [nTPM]":"73.2","Tissue RNA - small intestine [nTPM]":"1.9","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"0.4","Tissue RNA - spleen [nTPM]":"2.6","Tissue RNA - stomach 1 [nTPM]":"1.8","Tissue RNA - testis [nTPM]":"2.9","Tissue RNA - thalamus [nTPM]":"0.9","Tissue RNA - thymus [nTPM]":"1.3","Tissue RNA - thyroid gland [nTPM]":"2.7","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"40.4","Tissue RNA - urinary bladder [nTPM]":"1.3","Tissue RNA - vagina [nTPM]":"144.2","Tissue RNA - white matter [nTPM]":"0.9","Cell RNA - A-431 [nTPM]":"1.1","Cell RNA - A549 [nTPM]":"2.0","Cell RNA - AF22 [nTPM]":"1.1","Cell RNA - AN3-CA [nTPM]":"1.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.8","Cell RNA - BEWO [nTPM]":"17.5","Cell RNA - BJ [nTPM]":"0.4","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.6","Cell RNA - CACO-2 [nTPM]":"1.2","Cell RNA - CAPAN-2 [nTPM]":"1.7","Cell RNA - Daudi [nTPM]":"1.0","Cell RNA - EFO-21 [nTPM]":"2.3","Cell RNA - fHDF\/TERT166 [nTPM]":"1.3","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"24.2","Cell RNA - HAP1 [nTPM]":"2.8","Cell RNA - HBEC3-KT [nTPM]":"2.0","Cell RNA - HBF TERT88 [nTPM]":"0.6","Cell RNA - HDLM-2 [nTPM]":"2.0","Cell RNA - HEK 293 [nTPM]":"3.3","Cell RNA - HEL [nTPM]":"1.4","Cell RNA - HeLa [nTPM]":"16.2","Cell RNA - Hep G2 [nTPM]":"5.7","Cell RNA - HHSteC [nTPM]":"0.8","Cell RNA - HL-60 [nTPM]":"0.9","Cell RNA - HMC-1 [nTPM]":"1.5","Cell RNA - HSkMC [nTPM]":"1.5","Cell RNA - hTCEpi [nTPM]":"9.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.5","Cell RNA - hTERT-HME1 [nTPM]":"2.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.7","Cell RNA - JURKAT [nTPM]":"3.4","Cell RNA - K-562 [nTPM]":"1.0","Cell RNA - Karpas-707 [nTPM]":"1.0","Cell RNA - LHCN-M2 [nTPM]":"0.7","Cell RNA - MCF7 [nTPM]":"17.5","Cell RNA - MOLT-4 [nTPM]":"0.7","Cell RNA - NB-4 [nTPM]":"1.9","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"1.1","Cell RNA - PC-3 [nTPM]":"2.2","Cell RNA - REH [nTPM]":"1.1","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"1.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.6","Cell RNA - RT4 [nTPM]":"2.1","Cell RNA - SCLC-21H [nTPM]":"1.2","Cell RNA - SH-SY5Y [nTPM]":"1.6","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"21.7","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"1.4","Cell RNA - T-47d [nTPM]":"1.5","Cell RNA - THP-1 [nTPM]":"1.1","Cell RNA - TIME [nTPM]":"0.8","Cell RNA - U-138 MG [nTPM]":"1.1","Cell RNA - U-2 OS [nTPM]":"4.8","Cell RNA - U-2197 [nTPM]":"2.0","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"1.5","Cell RNA - U-266\/84 [nTPM]":"1.8","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"2.1","Cell RNA - WM-115 [nTPM]":"1.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.6","Brain RNA - basal ganglia [nTPM]":"0.8","Brain RNA - cerebellum [nTPM]":"3.7","Brain RNA - cerebral cortex [nTPM]":"2.0","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"1.5","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"1.4","Brain RNA - spinal cord [nTPM]":"0.4","Brain RNA - thalamus [nTPM]":"0.9","Brain RNA - white matter [nTPM]":"0.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"63.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"18.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"29.4","Single Cell Type RNA - Ductal cells [nTPM]":"2.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.8","Single Cell Type RNA - Fibroblasts [nTPM]":"3.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.6","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"34.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"1.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"6.2"},{"Gene":"TGM2","Gene synonym":["TGC"],"Ensembl":"ENSG00000198959","Gene description":"Transglutaminase 2","Uniprot":["P21980"],"Chromosome":"20","Position":"38127385-38166578","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Hydrolase","Protease","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"432.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"204.5","Cytotrophoblasts":"311.1","Ductal cells":"226.7","Endometrial stromal cells":"459.1","Hepatic stellate cells":"408.0","Hepatocytes":"205.7","Pancreatic endocrine cells":"326.5","Syncytiotrophoblasts":"374.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"CAPAN-2":"1546.7","EFO-21":"505.5","hTERT-RPE1":"994.3","HUVEC TERT2":"695.3","TIME":"924.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002598","HPA021019","HPA029518"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1700000","Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 36: Stromal cells - Cell proliferation","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB002598":null,"HPA021019":"AB_1858247","HPA029518":"AB_10603133"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.78e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.97e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.67e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-2"},"Tissue RNA - adipose tissue [nTPM]":"105.9","Tissue RNA - adrenal gland [nTPM]":"45.1","Tissue RNA - amygdala [nTPM]":"23.0","Tissue RNA - appendix [nTPM]":"68.4","Tissue RNA - basal ganglia [nTPM]":"22.3","Tissue RNA - bone marrow [nTPM]":"3.2","Tissue RNA - breast [nTPM]":"30.3","Tissue RNA - cerebellum [nTPM]":"22.9","Tissue RNA - cerebral cortex [nTPM]":"29.5","Tissue RNA - cervix [nTPM]":"432.0","Tissue RNA - choroid plexus [nTPM]":"53.0","Tissue RNA - colon [nTPM]":"30.6","Tissue RNA - duodenum [nTPM]":"29.8","Tissue RNA - endometrium 1 [nTPM]":"266.3","Tissue RNA - epididymis [nTPM]":"28.3","Tissue RNA - esophagus [nTPM]":"37.3","Tissue RNA - fallopian tube [nTPM]":"217.7","Tissue RNA - gallbladder [nTPM]":"127.7","Tissue RNA - heart muscle [nTPM]":"394.9","Tissue RNA - hippocampal formation [nTPM]":"21.4","Tissue RNA - hypothalamus [nTPM]":"23.0","Tissue RNA - kidney [nTPM]":"76.7","Tissue RNA - liver [nTPM]":"244.1","Tissue RNA - lung [nTPM]":"288.5","Tissue RNA - lymph node [nTPM]":"18.0","Tissue RNA - medulla oblongata [nTPM]":"25.4","Tissue RNA - midbrain [nTPM]":"22.5","Tissue RNA - ovary [nTPM]":"40.6","Tissue RNA - pancreas [nTPM]":"25.6","Tissue RNA - parathyroid gland [nTPM]":"19.3","Tissue RNA - pituitary gland [nTPM]":"95.9","Tissue RNA - placenta [nTPM]":"234.3","Tissue RNA - pons [nTPM]":"26.0","Tissue RNA - prostate [nTPM]":"88.7","Tissue RNA - rectum [nTPM]":"20.8","Tissue RNA - retina [nTPM]":"2.1","Tissue RNA - salivary gland [nTPM]":"9.8","Tissue RNA - seminal vesicle [nTPM]":"56.6","Tissue RNA - skeletal muscle [nTPM]":"63.9","Tissue RNA - skin 1 [nTPM]":"4.0","Tissue RNA - small intestine [nTPM]":"63.7","Tissue RNA - smooth muscle [nTPM]":"159.0","Tissue RNA - spinal cord [nTPM]":"24.4","Tissue RNA - spleen [nTPM]":"32.7","Tissue RNA - stomach 1 [nTPM]":"62.3","Tissue RNA - testis [nTPM]":"3.9","Tissue RNA - thalamus [nTPM]":"30.6","Tissue RNA - thymus [nTPM]":"15.4","Tissue RNA - thyroid gland [nTPM]":"36.3","Tissue RNA - tongue [nTPM]":"33.4","Tissue RNA - tonsil [nTPM]":"10.3","Tissue RNA - urinary bladder [nTPM]":"154.2","Tissue RNA - vagina [nTPM]":"87.8","Tissue RNA - white matter [nTPM]":"24.8","Cell RNA - A-431 [nTPM]":"65.0","Cell RNA - A549 [nTPM]":"47.5","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"1.8","Cell RNA - ASC diff [nTPM]":"47.3","Cell RNA - ASC TERT1 [nTPM]":"5.1","Cell RNA - BEWO [nTPM]":"24.0","Cell RNA - BJ [nTPM]":"95.5","Cell RNA - BJ hTERT+ [nTPM]":"45.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.8","Cell RNA - CACO-2 [nTPM]":"78.4","Cell RNA - CAPAN-2 [nTPM]":"1546.7","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"505.5","Cell RNA - fHDF\/TERT166 [nTPM]":"1.0","Cell RNA - GAMG [nTPM]":"105.4","Cell RNA - HaCaT [nTPM]":"1.7","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"221.7","Cell RNA - HBF TERT88 [nTPM]":"3.4","Cell RNA - HDLM-2 [nTPM]":"0.7","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"10.3","Cell RNA - HeLa [nTPM]":"2.6","Cell RNA - Hep G2 [nTPM]":"35.0","Cell RNA - HHSteC [nTPM]":"191.9","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"5.2","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"40.2","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"994.3","Cell RNA - HUVEC TERT2 [nTPM]":"695.3","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"21.4","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"16.0","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"0.9","Cell RNA - PC-3 [nTPM]":"4.6","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"69.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"1.3","Cell RNA - SiHa [nTPM]":"224.4","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"7.6","Cell RNA - SuSa [nTPM]":"31.6","Cell RNA - T-47d [nTPM]":"2.2","Cell RNA - THP-1 [nTPM]":"0.6","Cell RNA - TIME [nTPM]":"924.2","Cell RNA - U-138 MG [nTPM]":"1.6","Cell RNA - U-2 OS [nTPM]":"57.6","Cell RNA - U-2197 [nTPM]":"7.8","Cell RNA - U-251 MG [nTPM]":"46.3","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"0.8","Cell RNA - U-87 MG [nTPM]":"60.7","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"18.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"23.0","Brain RNA - basal ganglia [nTPM]":"22.3","Brain RNA - cerebellum [nTPM]":"22.9","Brain RNA - cerebral cortex [nTPM]":"29.5","Brain RNA - hippocampal formation [nTPM]":"21.4","Brain RNA - hypothalamus [nTPM]":"23.0","Brain RNA - medulla oblongata [nTPM]":"25.4","Brain RNA - midbrain [nTPM]":"22.5","Brain RNA - pons [nTPM]":"26.0","Brain RNA - spinal cord [nTPM]":"24.4","Brain RNA - thalamus [nTPM]":"30.6","Brain RNA - white matter [nTPM]":"24.8","Single Cell Type RNA - Adipocytes [nTPM]":"58.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"7.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"41.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"204.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"31.5","Single Cell Type RNA - Club cells [nTPM]":"55.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"311.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"226.7","Single Cell Type RNA - Early spermatids [nTPM]":"3.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"459.1","Single Cell Type RNA - Endothelial cells [nTPM]":"183.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"74.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"145.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"38.6","Single Cell Type RNA - Fibroblasts [nTPM]":"37.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.1","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"2.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"408.0","Single Cell Type RNA - Hepatocytes [nTPM]":"205.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"54.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.8","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"23.7","Single Cell Type RNA - Langerhans cells [nTPM]":"2.1","Single Cell Type RNA - Late spermatids [nTPM]":"5.0","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"35.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"28.1","Single Cell Type RNA - monocytes [nTPM]":"6.5","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"326.5","Single Cell Type RNA - Paneth cells [nTPM]":"1.1","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"68.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"63.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"27.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"49.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"4.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"374.2","Single Cell Type RNA - T-cells [nTPM]":"3.9","Single Cell Type RNA - Theca cells [nTPM]":"2.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.3","Single Cell Type RNA - Urothelial cells [nTPM]":"26.4"},{"Gene":"TGM3","Gene synonym":["TGE"],"Ensembl":"ENSG00000125780","Gene description":"Transglutaminase 3","Uniprot":["Q08188"],"Chromosome":"20","Position":"2296001-2341079","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Keratinization"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"esophagus":"1838.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Enteroendocrine cells":"46.2","Squamous epithelial cells":"22.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"head and neck cancer":"81.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"295","RNA blood cell specific nTPM":{"neutrophil":"30.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"303","RNA blood lineage specific nTPM":{"granulocytes":"30.3"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"14","RNA cell line specific nTPM":{"EFO-21":"5.2"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004728"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"14000000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 61: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA004728":"AB_1080360"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.67e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.6","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"1.4","Tissue RNA - breast [nTPM]":"3.9","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"54.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.8","Tissue RNA - esophagus [nTPM]":"1838.1","Tissue RNA - fallopian tube [nTPM]":"1.4","Tissue RNA - gallbladder [nTPM]":"2.2","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.8","Tissue RNA - lung [nTPM]":"0.5","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"1.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.6","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.6","Tissue RNA - rectum [nTPM]":"0.8","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"229.3","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"83.1","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"2.2","Tissue RNA - testis [nTPM]":"2.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"142.9","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"31.4","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"5.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"30.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"46.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"4.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"TGM5","Gene synonym":["TGMX","TGX"],"Ensembl":"ENSG00000104055","Gene description":"Transglutaminase 5","Uniprot":["O43548"],"Chromosome":"15","Position":"43232590-43266928","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"12.0","skin 1":"39.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"2.6","Club cells":"4.3","Early spermatids":"3.2","Late spermatids":"4.0","Suprabasal keratinocytes":"6.7","Urothelial cells":"12.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"2.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"HEL":"16.6"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"12","RNA mouse brain regional specific nTPM":{"cerebellum":"2.6"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-15"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.8","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"1.7","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"3.9","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"12.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"1.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"4.3","Tissue RNA - seminal vesicle [nTPM]":"1.2","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"39.3","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"2.3","Tissue RNA - urinary bladder [nTPM]":"0.5","Tissue RNA - vagina [nTPM]":"7.7","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"16.6","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.7","Cell RNA - HMC-1 [nTPM]":"2.3","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"2.5","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"2.4","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"1.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"4.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"3.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"4.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"12.1"},{"Gene":"TGM6","Gene synonym":["dJ734P14.3","SCA35","TGM3L","TGY"],"Ensembl":"ENSG00000166948","Gene description":"Transglutaminase 6","Uniprot":["O95932"],"Chromosome":"20","Position":"2380901-2432753","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"10","RNA pig brain regional specific nTPM":{"cerebellum":"1.0"},"Antibody":["HPA059196"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA059196":"AB_2683943"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"THG1L","Gene synonym":["FLJ11601","FLJ20546","hTHG1","ICF45","IHG-1"],"Ensembl":"ENSG00000113272","Gene description":"TRNA-histidine guanylyltransferase 1 like","Uniprot":["Q9NWX6"],"Chromosome":"5","Position":"157731420-157741449","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["tRNA processing"],"Molecular function":["Nucleotidyltransferase","Transferase"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035877","HPA035878"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 32: Non-specific - Translation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035877":"AB_10669979","HPA035878":"AB_10672993"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.93e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.8","Tissue RNA - adrenal gland [nTPM]":"4.9","Tissue RNA - amygdala [nTPM]":"2.3","Tissue RNA - appendix [nTPM]":"4.0","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"5.9","Tissue RNA - breast [nTPM]":"5.3","Tissue RNA - cerebellum [nTPM]":"2.7","Tissue RNA - cerebral cortex [nTPM]":"2.7","Tissue RNA - cervix [nTPM]":"5.2","Tissue RNA - choroid plexus [nTPM]":"2.2","Tissue RNA - colon [nTPM]":"6.9","Tissue RNA - duodenum [nTPM]":"5.5","Tissue RNA - endometrium 1 [nTPM]":"6.8","Tissue RNA - epididymis [nTPM]":"5.9","Tissue RNA - esophagus [nTPM]":"5.0","Tissue RNA - fallopian tube [nTPM]":"6.4","Tissue RNA - gallbladder [nTPM]":"4.7","Tissue RNA - heart muscle [nTPM]":"3.4","Tissue RNA - hippocampal formation [nTPM]":"2.2","Tissue RNA - hypothalamus [nTPM]":"2.7","Tissue RNA - kidney [nTPM]":"3.5","Tissue RNA - liver [nTPM]":"5.1","Tissue RNA - lung [nTPM]":"3.0","Tissue RNA - lymph node [nTPM]":"5.4","Tissue RNA - medulla oblongata [nTPM]":"2.6","Tissue RNA - midbrain [nTPM]":"2.4","Tissue RNA - ovary [nTPM]":"7.6","Tissue RNA - pancreas [nTPM]":"4.7","Tissue RNA - parathyroid gland [nTPM]":"3.1","Tissue RNA - pituitary gland [nTPM]":"3.2","Tissue RNA - placenta [nTPM]":"4.3","Tissue RNA - pons [nTPM]":"2.6","Tissue RNA - prostate [nTPM]":"4.0","Tissue RNA - rectum [nTPM]":"7.7","Tissue RNA - retina [nTPM]":"3.4","Tissue RNA - salivary gland [nTPM]":"3.1","Tissue RNA - seminal vesicle [nTPM]":"5.3","Tissue RNA - skeletal muscle [nTPM]":"3.9","Tissue RNA - skin 1 [nTPM]":"5.4","Tissue RNA - small intestine [nTPM]":"4.9","Tissue RNA - smooth muscle [nTPM]":"5.7","Tissue RNA - spinal cord [nTPM]":"2.1","Tissue RNA - spleen [nTPM]":"4.1","Tissue RNA - stomach 1 [nTPM]":"5.4","Tissue RNA - testis [nTPM]":"4.9","Tissue RNA - thalamus [nTPM]":"2.6","Tissue RNA - thymus [nTPM]":"5.3","Tissue RNA - thyroid gland [nTPM]":"6.7","Tissue RNA - tongue [nTPM]":"2.8","Tissue RNA - tonsil [nTPM]":"6.0","Tissue RNA - urinary bladder [nTPM]":"6.4","Tissue RNA - vagina [nTPM]":"4.6","Tissue RNA - white matter [nTPM]":"3.0","Cell RNA - A-431 [nTPM]":"8.8","Cell RNA - A549 [nTPM]":"15.4","Cell RNA - AF22 [nTPM]":"7.2","Cell RNA - AN3-CA [nTPM]":"13.8","Cell RNA - ASC diff [nTPM]":"6.7","Cell RNA - ASC TERT1 [nTPM]":"19.6","Cell RNA - BEWO [nTPM]":"5.5","Cell RNA - BJ [nTPM]":"6.8","Cell RNA - BJ hTERT+ [nTPM]":"12.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"18.1","Cell RNA - CACO-2 [nTPM]":"21.4","Cell RNA - CAPAN-2 [nTPM]":"8.7","Cell RNA - Daudi [nTPM]":"21.8","Cell RNA - EFO-21 [nTPM]":"5.7","Cell RNA - fHDF\/TERT166 [nTPM]":"6.0","Cell RNA - GAMG [nTPM]":"8.3","Cell RNA - HaCaT [nTPM]":"9.1","Cell RNA - HAP1 [nTPM]":"9.0","Cell RNA - HBEC3-KT [nTPM]":"13.1","Cell RNA - HBF TERT88 [nTPM]":"15.2","Cell RNA - HDLM-2 [nTPM]":"8.9","Cell RNA - HEK 293 [nTPM]":"12.0","Cell RNA - HEL [nTPM]":"7.7","Cell RNA - HeLa [nTPM]":"10.2","Cell RNA - Hep G2 [nTPM]":"9.1","Cell RNA - HHSteC [nTPM]":"7.6","Cell RNA - HL-60 [nTPM]":"16.6","Cell RNA - HMC-1 [nTPM]":"8.0","Cell RNA - HSkMC [nTPM]":"17.8","Cell RNA - hTCEpi [nTPM]":"15.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.1","Cell RNA - hTERT-HME1 [nTPM]":"16.6","Cell RNA - hTERT-RPE1 [nTPM]":"13.0","Cell RNA - HUVEC TERT2 [nTPM]":"5.1","Cell RNA - JURKAT [nTPM]":"3.4","Cell RNA - K-562 [nTPM]":"13.8","Cell RNA - Karpas-707 [nTPM]":"6.9","Cell RNA - LHCN-M2 [nTPM]":"8.2","Cell RNA - MCF7 [nTPM]":"12.1","Cell RNA - MOLT-4 [nTPM]":"2.0","Cell RNA - NB-4 [nTPM]":"11.3","Cell RNA - NTERA-2 [nTPM]":"6.9","Cell RNA - OE19 [nTPM]":"3.9","Cell RNA - PC-3 [nTPM]":"14.8","Cell RNA - REH [nTPM]":"3.3","Cell RNA - RH-30 [nTPM]":"13.8","Cell RNA - RPMI-8226 [nTPM]":"12.6","Cell RNA - RPTEC TERT1 [nTPM]":"8.5","Cell RNA - RT4 [nTPM]":"11.0","Cell RNA - SCLC-21H [nTPM]":"9.1","Cell RNA - SH-SY5Y [nTPM]":"12.8","Cell RNA - SiHa [nTPM]":"5.5","Cell RNA - SK-BR-3 [nTPM]":"8.2","Cell RNA - SK-MEL-30 [nTPM]":"11.3","Cell RNA - SuSa [nTPM]":"5.2","Cell RNA - T-47d [nTPM]":"13.9","Cell RNA - THP-1 [nTPM]":"9.5","Cell RNA - TIME [nTPM]":"5.8","Cell RNA - U-138 MG [nTPM]":"10.9","Cell RNA - U-2 OS [nTPM]":"7.2","Cell RNA - U-2197 [nTPM]":"9.2","Cell RNA - U-251 MG [nTPM]":"18.5","Cell RNA - U-266\/70 [nTPM]":"6.0","Cell RNA - U-266\/84 [nTPM]":"7.1","Cell RNA - U-698 [nTPM]":"14.0","Cell RNA - U-87 MG [nTPM]":"4.8","Cell RNA - U-937 [nTPM]":"15.9","Cell RNA - WM-115 [nTPM]":"6.9","Blood RNA - basophil [nTPM]":"3.9","Blood RNA - classical monocyte [nTPM]":"7.8","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"3.3","Blood RNA - intermediate monocyte [nTPM]":"8.7","Blood RNA - MAIT T-cell [nTPM]":"3.9","Blood RNA - memory B-cell [nTPM]":"5.7","Blood RNA - memory CD4 T-cell [nTPM]":"4.3","Blood RNA - memory CD8 T-cell [nTPM]":"3.4","Blood RNA - myeloid DC [nTPM]":"7.0","Blood RNA - naive B-cell [nTPM]":"4.6","Blood RNA - naive CD4 T-cell [nTPM]":"6.3","Blood RNA - naive CD8 T-cell [nTPM]":"5.3","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"6.7","Blood RNA - non-classical monocyte [nTPM]":"8.7","Blood RNA - plasmacytoid DC [nTPM]":"4.5","Blood RNA - T-reg [nTPM]":"5.0","Blood RNA - total PBMC [nTPM]":"3.9","Brain RNA - amygdala [nTPM]":"2.3","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"2.7","Brain RNA - cerebral cortex [nTPM]":"2.7","Brain RNA - hippocampal formation [nTPM]":"2.2","Brain RNA - hypothalamus [nTPM]":"2.7","Brain RNA - medulla oblongata [nTPM]":"2.6","Brain RNA - midbrain [nTPM]":"2.4","Brain RNA - pons [nTPM]":"2.6","Brain RNA - spinal cord [nTPM]":"2.1","Brain RNA - thalamus [nTPM]":"2.6","Brain RNA - white matter [nTPM]":"3.0","Single Cell Type RNA - Adipocytes [nTPM]":"6.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.6","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"14.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"27.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"27.9","Single Cell Type RNA - Bipolar cells [nTPM]":"2.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"11.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"17.6","Single Cell Type RNA - dendritic cells [nTPM]":"10.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"17.1","Single Cell Type RNA - Early spermatids [nTPM]":"19.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.8","Single Cell Type RNA - Endothelial cells [nTPM]":"9.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"23.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.8","Single Cell Type RNA - Fibroblasts [nTPM]":"15.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.2","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"17.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"8.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.3","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"15.7","Single Cell Type RNA - Langerhans cells [nTPM]":"17.9","Single Cell Type RNA - Late spermatids [nTPM]":"8.6","Single Cell Type RNA - Leydig cells [nTPM]":"14.3","Single Cell Type RNA - Macrophages [nTPM]":"16.2","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"21.2","Single Cell Type RNA - Muller glia cells [nTPM]":"2.0","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.1","Single Cell Type RNA - Paneth cells [nTPM]":"19.6","Single Cell Type RNA - Peritubular cells [nTPM]":"15.4","Single Cell Type RNA - Plasma cells [nTPM]":"13.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"21.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.4","Single Cell Type RNA - Spermatocytes [nTPM]":"19.8","Single Cell Type RNA - Spermatogonia [nTPM]":"8.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"24.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"13.8","Single Cell Type RNA - T-cells [nTPM]":"11.2","Single Cell Type RNA - Theca cells [nTPM]":"38.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.1","Single Cell Type RNA - Urothelial cells [nTPM]":"28.4"},{"Gene":"TKFC","Gene synonym":["DAK","DKFZP586B1621","NET45"],"Ensembl":"ENSG00000149476","Gene description":"Triokinase and FMN cyclase","Uniprot":["Q3LXA3"],"Chromosome":"11","Position":"61333220-61353295","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Lyase","Multifunctional enzyme","Transferase"],"Disease involvement":["Cataract"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"192.8","liver":"115.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"115.9","Proximal enterocytes":"415.8","Proximal tubular cells":"91.2","Theca cells":"93.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"133.2","RPMI-8226":"140.7","T-47d":"135.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039486","HPA048186"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6800000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA039486":"AB_10795402","HPA048186":"AB_2680305"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.32e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.38e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.5","Tissue RNA - adrenal gland [nTPM]":"82.8","Tissue RNA - amygdala [nTPM]":"5.9","Tissue RNA - appendix [nTPM]":"9.4","Tissue RNA - basal ganglia [nTPM]":"6.0","Tissue RNA - bone marrow [nTPM]":"16.6","Tissue RNA - breast [nTPM]":"12.1","Tissue RNA - cerebellum [nTPM]":"5.8","Tissue RNA - cerebral cortex [nTPM]":"6.6","Tissue RNA - cervix [nTPM]":"9.5","Tissue RNA - choroid plexus [nTPM]":"5.7","Tissue RNA - colon [nTPM]":"12.5","Tissue RNA - duodenum [nTPM]":"192.8","Tissue RNA - endometrium 1 [nTPM]":"11.0","Tissue RNA - epididymis [nTPM]":"7.6","Tissue RNA - esophagus [nTPM]":"16.3","Tissue RNA - fallopian tube [nTPM]":"15.4","Tissue RNA - gallbladder [nTPM]":"9.2","Tissue RNA - heart muscle [nTPM]":"7.6","Tissue RNA - hippocampal formation [nTPM]":"6.4","Tissue RNA - hypothalamus [nTPM]":"5.1","Tissue RNA - kidney [nTPM]":"45.5","Tissue RNA - liver [nTPM]":"115.8","Tissue RNA - lung [nTPM]":"9.0","Tissue RNA - lymph node [nTPM]":"13.6","Tissue RNA - medulla oblongata [nTPM]":"6.8","Tissue RNA - midbrain [nTPM]":"6.3","Tissue RNA - ovary [nTPM]":"10.3","Tissue RNA - pancreas [nTPM]":"24.0","Tissue RNA - parathyroid gland [nTPM]":"6.7","Tissue RNA - pituitary gland [nTPM]":"14.0","Tissue RNA - placenta [nTPM]":"6.1","Tissue RNA - pons [nTPM]":"6.2","Tissue RNA - prostate [nTPM]":"12.2","Tissue RNA - rectum [nTPM]":"5.7","Tissue RNA - retina [nTPM]":"5.6","Tissue RNA - salivary gland [nTPM]":"16.2","Tissue RNA - seminal vesicle [nTPM]":"8.9","Tissue RNA - skeletal muscle [nTPM]":"10.9","Tissue RNA - skin 1 [nTPM]":"17.8","Tissue RNA - small intestine [nTPM]":"138.0","Tissue RNA - smooth muscle [nTPM]":"5.2","Tissue RNA - spinal cord [nTPM]":"6.5","Tissue RNA - spleen [nTPM]":"13.0","Tissue RNA - stomach 1 [nTPM]":"16.6","Tissue RNA - testis [nTPM]":"28.2","Tissue RNA - thalamus [nTPM]":"6.0","Tissue RNA - thymus [nTPM]":"7.5","Tissue RNA - thyroid gland [nTPM]":"14.7","Tissue RNA - tongue [nTPM]":"5.6","Tissue RNA - tonsil [nTPM]":"8.0","Tissue RNA - urinary bladder [nTPM]":"10.9","Tissue RNA - vagina [nTPM]":"11.0","Tissue RNA - white matter [nTPM]":"7.2","Cell RNA - A-431 [nTPM]":"19.9","Cell RNA - A549 [nTPM]":"51.3","Cell RNA - AF22 [nTPM]":"8.5","Cell RNA - AN3-CA [nTPM]":"30.0","Cell RNA - ASC diff [nTPM]":"10.7","Cell RNA - ASC TERT1 [nTPM]":"11.4","Cell RNA - BEWO [nTPM]":"24.2","Cell RNA - BJ [nTPM]":"11.7","Cell RNA - BJ hTERT+ [nTPM]":"12.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.9","Cell RNA - CACO-2 [nTPM]":"23.1","Cell RNA - CAPAN-2 [nTPM]":"47.1","Cell RNA - Daudi [nTPM]":"25.0","Cell RNA - EFO-21 [nTPM]":"39.3","Cell RNA - fHDF\/TERT166 [nTPM]":"8.5","Cell RNA - GAMG [nTPM]":"11.0","Cell RNA - HaCaT [nTPM]":"27.7","Cell RNA - HAP1 [nTPM]":"16.3","Cell RNA - HBEC3-KT [nTPM]":"21.8","Cell RNA - HBF TERT88 [nTPM]":"3.5","Cell RNA - HDLM-2 [nTPM]":"42.5","Cell RNA - HEK 293 [nTPM]":"21.7","Cell RNA - HEL [nTPM]":"15.7","Cell RNA - HeLa [nTPM]":"26.2","Cell RNA - Hep G2 [nTPM]":"133.2","Cell RNA - HHSteC [nTPM]":"17.9","Cell RNA - HL-60 [nTPM]":"13.4","Cell RNA - HMC-1 [nTPM]":"25.0","Cell RNA - HSkMC [nTPM]":"18.2","Cell RNA - hTCEpi [nTPM]":"14.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.9","Cell RNA - hTERT-HME1 [nTPM]":"35.4","Cell RNA - hTERT-RPE1 [nTPM]":"9.4","Cell RNA - HUVEC TERT2 [nTPM]":"10.7","Cell RNA - JURKAT [nTPM]":"17.1","Cell RNA - K-562 [nTPM]":"27.2","Cell RNA - Karpas-707 [nTPM]":"46.7","Cell RNA - LHCN-M2 [nTPM]":"7.9","Cell RNA - MCF7 [nTPM]":"91.8","Cell RNA - MOLT-4 [nTPM]":"11.9","Cell RNA - NB-4 [nTPM]":"11.9","Cell RNA - NTERA-2 [nTPM]":"23.8","Cell RNA - OE19 [nTPM]":"19.2","Cell RNA - PC-3 [nTPM]":"33.8","Cell RNA - REH [nTPM]":"20.0","Cell RNA - RH-30 [nTPM]":"13.8","Cell RNA - RPMI-8226 [nTPM]":"140.7","Cell RNA - RPTEC TERT1 [nTPM]":"17.1","Cell RNA - RT4 [nTPM]":"35.0","Cell RNA - SCLC-21H [nTPM]":"33.0","Cell RNA - SH-SY5Y [nTPM]":"29.6","Cell RNA - SiHa [nTPM]":"21.0","Cell RNA - SK-BR-3 [nTPM]":"36.4","Cell RNA - SK-MEL-30 [nTPM]":"19.3","Cell RNA - SuSa [nTPM]":"6.0","Cell RNA - T-47d [nTPM]":"135.4","Cell RNA - THP-1 [nTPM]":"9.2","Cell RNA - TIME [nTPM]":"13.0","Cell RNA - U-138 MG [nTPM]":"21.0","Cell RNA - U-2 OS [nTPM]":"21.6","Cell RNA - U-2197 [nTPM]":"16.6","Cell RNA - U-251 MG [nTPM]":"7.0","Cell RNA - U-266\/70 [nTPM]":"85.8","Cell RNA - U-266\/84 [nTPM]":"76.5","Cell RNA - U-698 [nTPM]":"22.9","Cell RNA - U-87 MG [nTPM]":"21.3","Cell RNA - U-937 [nTPM]":"12.3","Cell RNA - WM-115 [nTPM]":"19.7","Blood RNA - basophil [nTPM]":"2.6","Blood RNA - classical monocyte [nTPM]":"13.4","Blood RNA - eosinophil [nTPM]":"6.5","Blood RNA - gdT-cell [nTPM]":"7.1","Blood RNA - intermediate monocyte [nTPM]":"7.8","Blood RNA - MAIT T-cell [nTPM]":"9.6","Blood RNA - memory B-cell [nTPM]":"10.3","Blood RNA - memory CD4 T-cell [nTPM]":"8.3","Blood RNA - memory CD8 T-cell [nTPM]":"7.1","Blood RNA - myeloid DC [nTPM]":"21.2","Blood RNA - naive B-cell [nTPM]":"9.7","Blood RNA - naive CD4 T-cell [nTPM]":"5.8","Blood RNA - naive CD8 T-cell [nTPM]":"6.2","Blood RNA - neutrophil [nTPM]":"1.2","Blood RNA - NK-cell [nTPM]":"6.5","Blood RNA - non-classical monocyte [nTPM]":"6.5","Blood RNA - plasmacytoid DC [nTPM]":"10.1","Blood RNA - T-reg [nTPM]":"12.9","Blood RNA - total PBMC [nTPM]":"9.7","Brain RNA - amygdala [nTPM]":"5.9","Brain RNA - basal ganglia [nTPM]":"6.0","Brain RNA - cerebellum [nTPM]":"5.8","Brain RNA - cerebral cortex [nTPM]":"6.6","Brain RNA - hippocampal formation [nTPM]":"6.4","Brain RNA - hypothalamus [nTPM]":"5.1","Brain RNA - medulla oblongata [nTPM]":"6.8","Brain RNA - midbrain [nTPM]":"6.3","Brain RNA - pons [nTPM]":"6.2","Brain RNA - spinal cord [nTPM]":"6.5","Brain RNA - thalamus [nTPM]":"6.0","Brain RNA - white matter [nTPM]":"7.2","Single Cell Type RNA - Adipocytes [nTPM]":"8.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"9.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"12.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"6.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"31.2","Single Cell Type RNA - dendritic cells [nTPM]":"8.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"29.4","Single Cell Type RNA - Ductal cells [nTPM]":"19.6","Single Cell Type RNA - Early spermatids [nTPM]":"16.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.6","Single Cell Type RNA - Endothelial cells [nTPM]":"8.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.3","Single Cell Type RNA - Erythroid cells [nTPM]":"7.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.2","Single Cell Type RNA - Fibroblasts [nTPM]":"11.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.1","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"10.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"115.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.1","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"17.2","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"12.0","Single Cell Type RNA - Leydig cells [nTPM]":"15.2","Single Cell Type RNA - Macrophages [nTPM]":"8.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"21.2","Single Cell Type RNA - Muller glia cells [nTPM]":"10.0","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.2","Single Cell Type RNA - Paneth cells [nTPM]":"32.9","Single Cell Type RNA - Peritubular cells [nTPM]":"22.6","Single Cell Type RNA - Plasma cells [nTPM]":"11.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"415.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"91.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.6","Single Cell Type RNA - Spermatocytes [nTPM]":"37.5","Single Cell Type RNA - Spermatogonia [nTPM]":"14.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.2","Single Cell Type RNA - T-cells [nTPM]":"6.5","Single Cell Type RNA - Theca cells [nTPM]":"93.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"47.6","Single Cell Type RNA - Urothelial cells [nTPM]":"13.4"},{"Gene":"TKT","Gene synonym":[],"Ensembl":"ENSG00000163931","Gene description":"Transketolase","Uniprot":["P29401"],"Chromosome":"3","Position":"53224712-53256052","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"667.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Kupffer cells":"696.7","monocytes":"624.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"classical monocyte":"447.9","eosinophil":"274.4","intermediate monocyte":"199.0","myeloid DC":"203.8","neutrophil":"375.3","non-classical monocyte":"242.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"dendritic cells":"203.8","granulocytes":"375.3","monocytes":"447.9"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029480","HPA029481"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"150000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA029480":"AB_10599307","HPA029481":"AB_10601895"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.21e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.90e-3"},"Tissue RNA - adipose tissue [nTPM]":"152.2","Tissue RNA - adrenal gland [nTPM]":"93.2","Tissue RNA - amygdala [nTPM]":"78.0","Tissue RNA - appendix [nTPM]":"66.2","Tissue RNA - basal ganglia [nTPM]":"80.0","Tissue RNA - bone marrow [nTPM]":"667.0","Tissue RNA - breast [nTPM]":"71.9","Tissue RNA - cerebellum [nTPM]":"93.2","Tissue RNA - cerebral cortex [nTPM]":"82.3","Tissue RNA - cervix [nTPM]":"59.7","Tissue RNA - choroid plexus [nTPM]":"60.5","Tissue RNA - colon [nTPM]":"73.2","Tissue RNA - duodenum [nTPM]":"84.2","Tissue RNA - endometrium 1 [nTPM]":"44.7","Tissue RNA - epididymis [nTPM]":"19.2","Tissue RNA - esophagus [nTPM]":"168.5","Tissue RNA - fallopian tube [nTPM]":"53.7","Tissue RNA - gallbladder [nTPM]":"97.2","Tissue RNA - heart muscle [nTPM]":"27.4","Tissue RNA - hippocampal formation [nTPM]":"72.3","Tissue RNA - hypothalamus [nTPM]":"96.9","Tissue RNA - kidney [nTPM]":"68.2","Tissue RNA - liver [nTPM]":"58.1","Tissue RNA - lung [nTPM]":"93.4","Tissue RNA - lymph node [nTPM]":"69.2","Tissue RNA - medulla oblongata [nTPM]":"89.2","Tissue RNA - midbrain [nTPM]":"89.9","Tissue RNA - ovary [nTPM]":"87.7","Tissue RNA - pancreas [nTPM]":"154.0","Tissue RNA - parathyroid gland [nTPM]":"41.4","Tissue RNA - pituitary gland [nTPM]":"45.6","Tissue RNA - placenta [nTPM]":"61.2","Tissue RNA - pons [nTPM]":"93.8","Tissue RNA - prostate [nTPM]":"48.8","Tissue RNA - rectum [nTPM]":"48.8","Tissue RNA - retina [nTPM]":"21.7","Tissue RNA - salivary gland [nTPM]":"54.9","Tissue RNA - seminal vesicle [nTPM]":"50.9","Tissue RNA - skeletal muscle [nTPM]":"12.8","Tissue RNA - skin 1 [nTPM]":"47.0","Tissue RNA - small intestine [nTPM]":"58.1","Tissue RNA - smooth muscle [nTPM]":"51.6","Tissue RNA - spinal cord [nTPM]":"77.4","Tissue RNA - spleen [nTPM]":"99.8","Tissue RNA - stomach 1 [nTPM]":"66.1","Tissue RNA - testis [nTPM]":"20.2","Tissue RNA - thalamus [nTPM]":"87.9","Tissue RNA - thymus [nTPM]":"82.9","Tissue RNA - thyroid gland [nTPM]":"116.1","Tissue RNA - tongue [nTPM]":"15.2","Tissue RNA - tonsil [nTPM]":"67.4","Tissue RNA - urinary bladder [nTPM]":"130.9","Tissue RNA - vagina [nTPM]":"85.5","Tissue RNA - white matter [nTPM]":"97.2","Cell RNA - A-431 [nTPM]":"313.0","Cell RNA - A549 [nTPM]":"1542.9","Cell RNA - AF22 [nTPM]":"216.0","Cell RNA - AN3-CA [nTPM]":"241.5","Cell RNA - ASC diff [nTPM]":"470.8","Cell RNA - ASC TERT1 [nTPM]":"570.8","Cell RNA - BEWO [nTPM]":"439.5","Cell RNA - BJ [nTPM]":"206.2","Cell RNA - BJ hTERT+ [nTPM]":"353.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"348.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"330.8","Cell RNA - CACO-2 [nTPM]":"430.1","Cell RNA - CAPAN-2 [nTPM]":"779.3","Cell RNA - Daudi [nTPM]":"388.5","Cell RNA - EFO-21 [nTPM]":"96.8","Cell RNA - fHDF\/TERT166 [nTPM]":"302.9","Cell RNA - GAMG [nTPM]":"673.3","Cell RNA - HaCaT [nTPM]":"438.3","Cell RNA - HAP1 [nTPM]":"377.9","Cell RNA - HBEC3-KT [nTPM]":"775.8","Cell RNA - HBF TERT88 [nTPM]":"102.4","Cell RNA - HDLM-2 [nTPM]":"131.0","Cell RNA - HEK 293 [nTPM]":"210.3","Cell RNA - HEL [nTPM]":"259.6","Cell RNA - HeLa [nTPM]":"1022.2","Cell RNA - Hep G2 [nTPM]":"655.2","Cell RNA - HHSteC [nTPM]":"573.9","Cell RNA - HL-60 [nTPM]":"321.4","Cell RNA - HMC-1 [nTPM]":"168.1","Cell RNA - HSkMC [nTPM]":"416.0","Cell RNA - hTCEpi [nTPM]":"437.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"418.5","Cell RNA - hTERT-HME1 [nTPM]":"213.7","Cell RNA - hTERT-RPE1 [nTPM]":"949.2","Cell RNA - HUVEC TERT2 [nTPM]":"444.9","Cell RNA - JURKAT [nTPM]":"323.8","Cell RNA - K-562 [nTPM]":"188.3","Cell RNA - Karpas-707 [nTPM]":"164.7","Cell RNA - LHCN-M2 [nTPM]":"144.5","Cell RNA - MCF7 [nTPM]":"381.6","Cell RNA - MOLT-4 [nTPM]":"338.6","Cell RNA - NB-4 [nTPM]":"358.1","Cell RNA - NTERA-2 [nTPM]":"737.1","Cell RNA - OE19 [nTPM]":"603.0","Cell RNA - PC-3 [nTPM]":"367.9","Cell RNA - REH [nTPM]":"201.1","Cell RNA - RH-30 [nTPM]":"98.5","Cell RNA - RPMI-8226 [nTPM]":"726.2","Cell RNA - RPTEC TERT1 [nTPM]":"550.3","Cell RNA - RT4 [nTPM]":"520.2","Cell RNA - SCLC-21H [nTPM]":"139.6","Cell RNA - SH-SY5Y [nTPM]":"103.7","Cell RNA - SiHa [nTPM]":"383.4","Cell RNA - SK-BR-3 [nTPM]":"605.3","Cell RNA - SK-MEL-30 [nTPM]":"365.1","Cell RNA - SuSa [nTPM]":"656.7","Cell RNA - T-47d [nTPM]":"188.8","Cell RNA - THP-1 [nTPM]":"437.4","Cell RNA - TIME [nTPM]":"335.9","Cell RNA - U-138 MG [nTPM]":"107.2","Cell RNA - U-2 OS [nTPM]":"164.2","Cell RNA - U-2197 [nTPM]":"320.0","Cell RNA - U-251 MG [nTPM]":"401.9","Cell RNA - U-266\/70 [nTPM]":"94.5","Cell RNA - U-266\/84 [nTPM]":"190.3","Cell RNA - U-698 [nTPM]":"235.7","Cell RNA - U-87 MG [nTPM]":"234.4","Cell RNA - U-937 [nTPM]":"321.0","Cell RNA - WM-115 [nTPM]":"203.8","Blood RNA - basophil [nTPM]":"51.5","Blood RNA - classical monocyte [nTPM]":"447.9","Blood RNA - eosinophil [nTPM]":"274.4","Blood RNA - gdT-cell [nTPM]":"17.8","Blood RNA - intermediate monocyte [nTPM]":"199.0","Blood RNA - MAIT T-cell [nTPM]":"22.8","Blood RNA - memory B-cell [nTPM]":"39.7","Blood RNA - memory CD4 T-cell [nTPM]":"25.8","Blood RNA - memory CD8 T-cell [nTPM]":"20.6","Blood RNA - myeloid DC [nTPM]":"203.8","Blood RNA - naive B-cell [nTPM]":"21.1","Blood RNA - naive CD4 T-cell [nTPM]":"26.6","Blood RNA - naive CD8 T-cell [nTPM]":"20.7","Blood RNA - neutrophil [nTPM]":"375.3","Blood RNA - NK-cell [nTPM]":"30.8","Blood RNA - non-classical monocyte [nTPM]":"242.6","Blood RNA - plasmacytoid DC [nTPM]":"34.4","Blood RNA - T-reg [nTPM]":"36.7","Blood RNA - total PBMC [nTPM]":"312.4","Brain RNA - amygdala [nTPM]":"78.0","Brain RNA - basal ganglia [nTPM]":"80.0","Brain RNA - cerebellum [nTPM]":"93.2","Brain RNA - cerebral cortex [nTPM]":"82.3","Brain RNA - hippocampal formation [nTPM]":"72.3","Brain RNA - hypothalamus [nTPM]":"96.9","Brain RNA - medulla oblongata [nTPM]":"89.2","Brain RNA - midbrain [nTPM]":"89.9","Brain RNA - pons [nTPM]":"93.8","Brain RNA - spinal cord [nTPM]":"77.4","Brain RNA - thalamus [nTPM]":"87.9","Brain RNA - white matter [nTPM]":"97.2","Single Cell Type RNA - Adipocytes [nTPM]":"79.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"134.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"125.6","Single Cell Type RNA - Astrocytes [nTPM]":"46.7","Single Cell Type RNA - B-cells [nTPM]":"92.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"79.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"384.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"325.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"287.4","Single Cell Type RNA - Bipolar cells [nTPM]":"41.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"99.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"80.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"75.8","Single Cell Type RNA - Club cells [nTPM]":"149.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"62.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"349.0","Single Cell Type RNA - dendritic cells [nTPM]":"69.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"139.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"80.3","Single Cell Type RNA - Ductal cells [nTPM]":"197.7","Single Cell Type RNA - Early spermatids [nTPM]":"6.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"87.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"79.6","Single Cell Type RNA - Endothelial cells [nTPM]":"81.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"52.6","Single Cell Type RNA - Erythroid cells [nTPM]":"150.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"269.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"249.8","Single Cell Type RNA - Fibroblasts [nTPM]":"80.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"168.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"95.5","Single Cell Type RNA - granulocytes [nTPM]":"62.7","Single Cell Type RNA - Granulosa cells [nTPM]":"123.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"75.0","Single Cell Type RNA - Hepatocytes [nTPM]":"83.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"256.0","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"23.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"149.6","Single Cell Type RNA - Ionocytes [nTPM]":"142.4","Single Cell Type RNA - Kupffer cells [nTPM]":"696.7","Single Cell Type RNA - Langerhans cells [nTPM]":"110.5","Single Cell Type RNA - Late spermatids [nTPM]":"8.9","Single Cell Type RNA - Leydig cells [nTPM]":"157.2","Single Cell Type RNA - Macrophages [nTPM]":"333.3","Single Cell Type RNA - Melanocytes [nTPM]":"76.5","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"624.4","Single Cell Type RNA - Muller glia cells [nTPM]":"88.8","Single Cell Type RNA - NK-cells [nTPM]":"46.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"39.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"193.6","Single Cell Type RNA - Paneth cells [nTPM]":"81.4","Single Cell Type RNA - Peritubular cells [nTPM]":"106.8","Single Cell Type RNA - Plasma cells [nTPM]":"109.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"337.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"141.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"219.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"99.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"46.3","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"35.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"102.1","Single Cell Type RNA - Spermatocytes [nTPM]":"16.8","Single Cell Type RNA - Spermatogonia [nTPM]":"30.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"409.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"67.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"413.6","Single Cell Type RNA - T-cells [nTPM]":"78.8","Single Cell Type RNA - Theca cells [nTPM]":"427.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"276.7","Single Cell Type RNA - Urothelial cells [nTPM]":"413.6"},{"Gene":"TLK2","Gene synonym":["MGC44450","PKU-ALPHA"],"Ensembl":"ENSG00000146872","Gene description":"Tousled like kinase 2","Uniprot":["Q86UE8"],"Chromosome":"17","Position":"62458658-62615481","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA damage"],"Molecular function":["Chromatin regulator","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"173.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.40e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-2"},"Tissue RNA - adipose tissue [nTPM]":"19.9","Tissue RNA - adrenal gland [nTPM]":"16.9","Tissue RNA - amygdala [nTPM]":"7.5","Tissue RNA - appendix [nTPM]":"21.1","Tissue RNA - basal ganglia [nTPM]":"14.9","Tissue RNA - bone marrow [nTPM]":"36.1","Tissue RNA - breast [nTPM]":"11.8","Tissue RNA - cerebellum [nTPM]":"19.8","Tissue RNA - cerebral cortex [nTPM]":"12.0","Tissue RNA - cervix [nTPM]":"12.4","Tissue RNA - choroid plexus [nTPM]":"9.5","Tissue RNA - colon [nTPM]":"21.7","Tissue RNA - duodenum [nTPM]":"20.5","Tissue RNA - endometrium 1 [nTPM]":"22.9","Tissue RNA - epididymis [nTPM]":"8.7","Tissue RNA - esophagus [nTPM]":"23.6","Tissue RNA - fallopian tube [nTPM]":"13.2","Tissue RNA - gallbladder [nTPM]":"20.9","Tissue RNA - heart muscle [nTPM]":"22.6","Tissue RNA - hippocampal formation [nTPM]":"9.8","Tissue RNA - hypothalamus [nTPM]":"17.5","Tissue RNA - kidney [nTPM]":"15.2","Tissue RNA - liver [nTPM]":"12.5","Tissue RNA - lung [nTPM]":"16.2","Tissue RNA - lymph node [nTPM]":"25.5","Tissue RNA - medulla oblongata [nTPM]":"18.1","Tissue RNA - midbrain [nTPM]":"14.2","Tissue RNA - ovary [nTPM]":"21.6","Tissue RNA - pancreas [nTPM]":"18.0","Tissue RNA - parathyroid gland [nTPM]":"16.0","Tissue RNA - pituitary gland [nTPM]":"9.8","Tissue RNA - placenta [nTPM]":"17.4","Tissue RNA - pons [nTPM]":"14.4","Tissue RNA - prostate [nTPM]":"16.0","Tissue RNA - rectum [nTPM]":"14.8","Tissue RNA - retina [nTPM]":"43.4","Tissue RNA - salivary gland [nTPM]":"16.5","Tissue RNA - seminal vesicle [nTPM]":"11.4","Tissue RNA - skeletal muscle [nTPM]":"32.4","Tissue RNA - skin 1 [nTPM]":"23.7","Tissue RNA - small intestine [nTPM]":"20.5","Tissue RNA - smooth muscle [nTPM]":"16.1","Tissue RNA - spinal cord [nTPM]":"10.0","Tissue RNA - spleen [nTPM]":"21.4","Tissue RNA - stomach 1 [nTPM]":"18.6","Tissue RNA - testis [nTPM]":"52.1","Tissue RNA - thalamus [nTPM]":"12.8","Tissue RNA - thymus [nTPM]":"23.2","Tissue RNA - thyroid gland [nTPM]":"30.0","Tissue RNA - tongue [nTPM]":"21.8","Tissue RNA - tonsil [nTPM]":"17.2","Tissue RNA - urinary bladder [nTPM]":"19.1","Tissue RNA - vagina [nTPM]":"10.9","Tissue RNA - white matter [nTPM]":"25.5","Cell RNA - A-431 [nTPM]":"40.9","Cell RNA - A549 [nTPM]":"36.9","Cell RNA - AF22 [nTPM]":"62.2","Cell RNA - AN3-CA [nTPM]":"66.4","Cell RNA - ASC diff [nTPM]":"20.3","Cell RNA - ASC TERT1 [nTPM]":"26.0","Cell RNA - BEWO [nTPM]":"36.6","Cell RNA - BJ [nTPM]":"44.1","Cell RNA - BJ hTERT+ [nTPM]":"34.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"51.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"46.6","Cell RNA - CACO-2 [nTPM]":"39.0","Cell RNA - CAPAN-2 [nTPM]":"35.7","Cell RNA - Daudi [nTPM]":"79.0","Cell RNA - EFO-21 [nTPM]":"22.0","Cell RNA - fHDF\/TERT166 [nTPM]":"29.2","Cell RNA - GAMG [nTPM]":"45.1","Cell RNA - HaCaT [nTPM]":"27.2","Cell RNA - HAP1 [nTPM]":"45.1","Cell RNA - HBEC3-KT [nTPM]":"19.0","Cell RNA - HBF TERT88 [nTPM]":"48.9","Cell RNA - HDLM-2 [nTPM]":"42.3","Cell RNA - HEK 293 [nTPM]":"36.1","Cell RNA - HEL [nTPM]":"54.2","Cell RNA - HeLa [nTPM]":"33.6","Cell RNA - Hep G2 [nTPM]":"39.2","Cell RNA - HHSteC [nTPM]":"36.2","Cell RNA - HL-60 [nTPM]":"57.9","Cell RNA - HMC-1 [nTPM]":"33.1","Cell RNA - HSkMC [nTPM]":"22.7","Cell RNA - hTCEpi [nTPM]":"25.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"34.7","Cell RNA - hTERT-HME1 [nTPM]":"41.7","Cell RNA - hTERT-RPE1 [nTPM]":"31.2","Cell RNA - HUVEC TERT2 [nTPM]":"25.9","Cell RNA - JURKAT [nTPM]":"44.9","Cell RNA - K-562 [nTPM]":"54.4","Cell RNA - Karpas-707 [nTPM]":"36.0","Cell RNA - LHCN-M2 [nTPM]":"28.3","Cell RNA - MCF7 [nTPM]":"89.2","Cell RNA - MOLT-4 [nTPM]":"82.7","Cell RNA - NB-4 [nTPM]":"22.0","Cell RNA - NTERA-2 [nTPM]":"39.8","Cell RNA - OE19 [nTPM]":"24.4","Cell RNA - PC-3 [nTPM]":"30.9","Cell RNA - REH [nTPM]":"55.9","Cell RNA - RH-30 [nTPM]":"81.8","Cell RNA - RPMI-8226 [nTPM]":"25.7","Cell RNA - RPTEC TERT1 [nTPM]":"24.9","Cell RNA - RT4 [nTPM]":"40.7","Cell RNA - SCLC-21H [nTPM]":"66.9","Cell RNA - SH-SY5Y [nTPM]":"90.6","Cell RNA - SiHa [nTPM]":"37.6","Cell RNA - SK-BR-3 [nTPM]":"25.5","Cell RNA - SK-MEL-30 [nTPM]":"57.1","Cell RNA - SuSa [nTPM]":"52.0","Cell RNA - T-47d [nTPM]":"43.2","Cell RNA - THP-1 [nTPM]":"51.8","Cell RNA - TIME [nTPM]":"34.9","Cell RNA - U-138 MG [nTPM]":"71.2","Cell RNA - U-2 OS [nTPM]":"66.9","Cell RNA - U-2197 [nTPM]":"32.5","Cell RNA - U-251 MG [nTPM]":"50.6","Cell RNA - U-266\/70 [nTPM]":"40.1","Cell RNA - U-266\/84 [nTPM]":"54.5","Cell RNA - U-698 [nTPM]":"72.3","Cell RNA - U-87 MG [nTPM]":"29.4","Cell RNA - U-937 [nTPM]":"29.1","Cell RNA - WM-115 [nTPM]":"38.2","Blood RNA - basophil [nTPM]":"2.5","Blood RNA - classical monocyte [nTPM]":"1.4","Blood RNA - eosinophil [nTPM]":"4.9","Blood RNA - gdT-cell [nTPM]":"1.2","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"1.3","Blood RNA - memory B-cell [nTPM]":"2.2","Blood RNA - memory CD4 T-cell [nTPM]":"2.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.5","Blood RNA - myeloid DC [nTPM]":"1.3","Blood RNA - naive B-cell [nTPM]":"2.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"2.3","Blood RNA - neutrophil [nTPM]":"2.8","Blood RNA - NK-cell [nTPM]":"3.9","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"1.9","Blood RNA - T-reg [nTPM]":"2.8","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"7.5","Brain RNA - basal ganglia [nTPM]":"14.9","Brain RNA - cerebellum [nTPM]":"19.8","Brain RNA - cerebral cortex [nTPM]":"12.0","Brain RNA - hippocampal formation [nTPM]":"9.8","Brain RNA - hypothalamus [nTPM]":"17.5","Brain RNA - medulla oblongata [nTPM]":"18.1","Brain RNA - midbrain [nTPM]":"14.2","Brain RNA - pons [nTPM]":"14.4","Brain RNA - spinal cord [nTPM]":"10.0","Brain RNA - thalamus [nTPM]":"12.8","Brain RNA - white matter [nTPM]":"25.5","Single Cell Type RNA - Adipocytes [nTPM]":"27.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.7","Single Cell Type RNA - Astrocytes [nTPM]":"33.6","Single Cell Type RNA - B-cells [nTPM]":"22.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"22.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"62.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"27.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"11.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"83.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.5","Single Cell Type RNA - dendritic cells [nTPM]":"29.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"19.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"10.3","Single Cell Type RNA - Early spermatids [nTPM]":"107.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"28.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"34.4","Single Cell Type RNA - Endothelial cells [nTPM]":"22.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.0","Single Cell Type RNA - Erythroid cells [nTPM]":"23.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"37.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.0","Single Cell Type RNA - Fibroblasts [nTPM]":"19.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"36.4","Single Cell Type RNA - granulocytes [nTPM]":"20.8","Single Cell Type RNA - Granulosa cells [nTPM]":"27.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"10.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.5","Single Cell Type RNA - Horizontal cells [nTPM]":"28.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.0","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"18.2","Single Cell Type RNA - Langerhans cells [nTPM]":"19.7","Single Cell Type RNA - Late spermatids [nTPM]":"173.0","Single Cell Type RNA - Leydig cells [nTPM]":"21.1","Single Cell Type RNA - Macrophages [nTPM]":"22.0","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"37.5","Single Cell Type RNA - monocytes [nTPM]":"15.1","Single Cell Type RNA - Muller glia cells [nTPM]":"22.4","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"45.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"67.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.7","Single Cell Type RNA - Paneth cells [nTPM]":"21.8","Single Cell Type RNA - Peritubular cells [nTPM]":"17.7","Single Cell Type RNA - Plasma cells [nTPM]":"24.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"21.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"27.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"84.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.9","Single Cell Type RNA - Spermatocytes [nTPM]":"81.7","Single Cell Type RNA - Spermatogonia [nTPM]":"38.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.2","Single Cell Type RNA - T-cells [nTPM]":"21.4","Single Cell Type RNA - Theca cells [nTPM]":"30.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.8","Single Cell Type RNA - Urothelial cells [nTPM]":"21.3"},{"Gene":"TM4SF20","Gene synonym":["FLJ22800","TCCE518"],"Ensembl":"ENSG00000168955","Gene description":"Transmembrane 4 L six family member 20","Uniprot":["Q53R12"],"Chromosome":"2","Position":"227362038-227381995","Protein class":["Disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Autism spectrum disorder"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"76","RNA tissue specific nTPM":{"intestine":"266.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Proximal enterocytes":"703.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"colorectal cancer":"5.0","liver cancer":"4.7","pancreatic cancer":"5.5","stomach cancer":"11.8"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"1.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"2.6","RPMI-8226":"1.7"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051838","HPA063184","HPA065531"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Focal adhesion sites"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Plasma membrane","Focal adhesion sites"],"Subcellular additional location":null,"Antibody RRID":{"HPA051838":"AB_2681631","HPA063184":"AB_2684958","HPA065531":"AB_2685506"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-3"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"1.2","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.4","Tissue RNA - colon [nTPM]":"3.1","Tissue RNA - duodenum [nTPM]":"266.6","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"3.9","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"144.5","Tissue RNA - smooth muscle [nTPM]":"1.6","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"3.5","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"2.6","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.6","Cell RNA - SiHa [nTPM]":"0.4","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.7","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"1.2","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"48.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"77.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"157.9","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"703.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.8","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"TMC1","Gene synonym":["DFNA36","DFNB11","DFNB7"],"Ensembl":"ENSG00000165091","Gene description":"Transmembrane channel like 1","Uniprot":["Q8TDI8"],"Chromosome":"9","Position":"72521608-72838297","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Hearing","Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"1.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"19.2","Early spermatids":"7.9","Endometrial stromal cells":"5.5","Microglial cells":"5.6","Urothelial cells":"6.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"2.7","HAP1":"5.2","NTERA-2":"1.9","SuSa":"1.0","U-266\/70":"1.3","U-266\/84":"1.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"1.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.8","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"0.7","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.6","Tissue RNA - midbrain [nTPM]":"0.6","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"0.6","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"2.7","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"5.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.9","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"1.3","Cell RNA - U-266\/84 [nTPM]":"1.4","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"0.6","Brain RNA - midbrain [nTPM]":"0.6","Brain RNA - pons [nTPM]":"0.6","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"0.7","Single Cell Type RNA - Adipocytes [nTPM]":"1.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"19.2","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"7.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.5","Single Cell Type RNA - Endothelial cells [nTPM]":"1.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.8","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"1.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"2.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"1.8","Single Cell Type RNA - Spermatogonia [nTPM]":"3.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.6","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"6.8"},{"Gene":"TMC6","Gene synonym":["EVER1","EVIN1","LAK-4P","TNRC6C-AS1"],"Ensembl":"ENSG00000141524","Gene description":"Transmembrane channel like 6","Uniprot":["Q7Z403"],"Chromosome":"17","Position":"78107397-78132407","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"110.5"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"K-562":"108.7","SK-BR-3":"121.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051430"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051430":"AB_2681483"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.82e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.20e-4"},"Tissue RNA - adipose tissue [nTPM]":"29.5","Tissue RNA - adrenal gland [nTPM]":"6.8","Tissue RNA - amygdala [nTPM]":"19.2","Tissue RNA - appendix [nTPM]":"45.4","Tissue RNA - basal ganglia [nTPM]":"50.5","Tissue RNA - bone marrow [nTPM]":"72.7","Tissue RNA - breast [nTPM]":"25.2","Tissue RNA - cerebellum [nTPM]":"43.4","Tissue RNA - cerebral cortex [nTPM]":"33.5","Tissue RNA - cervix [nTPM]":"11.3","Tissue RNA - choroid plexus [nTPM]":"5.2","Tissue RNA - colon [nTPM]":"23.5","Tissue RNA - duodenum [nTPM]":"21.7","Tissue RNA - endometrium 1 [nTPM]":"7.6","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"25.4","Tissue RNA - fallopian tube [nTPM]":"14.1","Tissue RNA - gallbladder [nTPM]":"9.7","Tissue RNA - heart muscle [nTPM]":"35.9","Tissue RNA - hippocampal formation [nTPM]":"19.3","Tissue RNA - hypothalamus [nTPM]":"26.4","Tissue RNA - kidney [nTPM]":"20.6","Tissue RNA - liver [nTPM]":"9.1","Tissue RNA - lung [nTPM]":"40.3","Tissue RNA - lymph node [nTPM]":"69.7","Tissue RNA - medulla oblongata [nTPM]":"59.3","Tissue RNA - midbrain [nTPM]":"49.7","Tissue RNA - ovary [nTPM]":"3.8","Tissue RNA - pancreas [nTPM]":"14.6","Tissue RNA - parathyroid gland [nTPM]":"3.1","Tissue RNA - pituitary gland [nTPM]":"5.6","Tissue RNA - placenta [nTPM]":"8.8","Tissue RNA - pons [nTPM]":"55.9","Tissue RNA - prostate [nTPM]":"20.2","Tissue RNA - rectum [nTPM]":"6.6","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"29.3","Tissue RNA - seminal vesicle [nTPM]":"7.9","Tissue RNA - skeletal muscle [nTPM]":"3.5","Tissue RNA - skin 1 [nTPM]":"17.9","Tissue RNA - small intestine [nTPM]":"50.6","Tissue RNA - smooth muscle [nTPM]":"3.5","Tissue RNA - spinal cord [nTPM]":"35.8","Tissue RNA - spleen [nTPM]":"110.5","Tissue RNA - stomach 1 [nTPM]":"14.6","Tissue RNA - testis [nTPM]":"2.6","Tissue RNA - thalamus [nTPM]":"48.4","Tissue RNA - thymus [nTPM]":"26.3","Tissue RNA - thyroid gland [nTPM]":"12.9","Tissue RNA - tongue [nTPM]":"1.8","Tissue RNA - tonsil [nTPM]":"32.4","Tissue RNA - urinary bladder [nTPM]":"14.6","Tissue RNA - vagina [nTPM]":"18.4","Tissue RNA - white matter [nTPM]":"81.9","Cell RNA - A-431 [nTPM]":"17.9","Cell RNA - A549 [nTPM]":"14.0","Cell RNA - AF22 [nTPM]":"7.5","Cell RNA - AN3-CA [nTPM]":"6.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"15.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"25.2","Cell RNA - CAPAN-2 [nTPM]":"19.2","Cell RNA - Daudi [nTPM]":"19.7","Cell RNA - EFO-21 [nTPM]":"23.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"6.3","Cell RNA - HaCaT [nTPM]":"31.0","Cell RNA - HAP1 [nTPM]":"1.0","Cell RNA - HBEC3-KT [nTPM]":"5.9","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"2.0","Cell RNA - HEK 293 [nTPM]":"11.3","Cell RNA - HEL [nTPM]":"41.3","Cell RNA - HeLa [nTPM]":"4.2","Cell RNA - Hep G2 [nTPM]":"31.0","Cell RNA - HHSteC [nTPM]":"1.9","Cell RNA - HL-60 [nTPM]":"38.3","Cell RNA - HMC-1 [nTPM]":"67.0","Cell RNA - HSkMC [nTPM]":"1.1","Cell RNA - hTCEpi [nTPM]":"16.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"1.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"14.7","Cell RNA - JURKAT [nTPM]":"9.2","Cell RNA - K-562 [nTPM]":"108.7","Cell RNA - Karpas-707 [nTPM]":"73.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"36.1","Cell RNA - MOLT-4 [nTPM]":"18.9","Cell RNA - NB-4 [nTPM]":"65.4","Cell RNA - NTERA-2 [nTPM]":"5.9","Cell RNA - OE19 [nTPM]":"32.9","Cell RNA - PC-3 [nTPM]":"4.9","Cell RNA - REH [nTPM]":"8.4","Cell RNA - RH-30 [nTPM]":"0.6","Cell RNA - RPMI-8226 [nTPM]":"58.9","Cell RNA - RPTEC TERT1 [nTPM]":"11.4","Cell RNA - RT4 [nTPM]":"65.1","Cell RNA - SCLC-21H [nTPM]":"1.9","Cell RNA - SH-SY5Y [nTPM]":"4.9","Cell RNA - SiHa [nTPM]":"5.7","Cell RNA - SK-BR-3 [nTPM]":"121.0","Cell RNA - SK-MEL-30 [nTPM]":"33.2","Cell RNA - SuSa [nTPM]":"9.7","Cell RNA - T-47d [nTPM]":"68.7","Cell RNA - THP-1 [nTPM]":"57.6","Cell RNA - TIME [nTPM]":"5.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"8.7","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"57.6","Cell RNA - U-266\/84 [nTPM]":"27.3","Cell RNA - U-698 [nTPM]":"13.2","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"60.4","Cell RNA - WM-115 [nTPM]":"1.0","Blood RNA - basophil [nTPM]":"17.7","Blood RNA - classical monocyte [nTPM]":"11.6","Blood RNA - eosinophil [nTPM]":"23.2","Blood RNA - gdT-cell [nTPM]":"56.2","Blood RNA - intermediate monocyte [nTPM]":"38.3","Blood RNA - MAIT T-cell [nTPM]":"49.0","Blood RNA - memory B-cell [nTPM]":"28.5","Blood RNA - memory CD4 T-cell [nTPM]":"41.7","Blood RNA - memory CD8 T-cell [nTPM]":"46.2","Blood RNA - myeloid DC [nTPM]":"18.6","Blood RNA - naive B-cell [nTPM]":"21.7","Blood RNA - naive CD4 T-cell [nTPM]":"36.5","Blood RNA - naive CD8 T-cell [nTPM]":"39.6","Blood RNA - neutrophil [nTPM]":"15.3","Blood RNA - NK-cell [nTPM]":"35.8","Blood RNA - non-classical monocyte [nTPM]":"63.5","Blood RNA - plasmacytoid DC [nTPM]":"5.7","Blood RNA - T-reg [nTPM]":"38.0","Blood RNA - total PBMC [nTPM]":"33.5","Brain RNA - amygdala [nTPM]":"19.2","Brain RNA - basal ganglia [nTPM]":"50.5","Brain RNA - cerebellum [nTPM]":"43.4","Brain RNA - cerebral cortex [nTPM]":"33.5","Brain RNA - hippocampal formation [nTPM]":"19.3","Brain RNA - hypothalamus [nTPM]":"26.4","Brain RNA - medulla oblongata [nTPM]":"59.3","Brain RNA - midbrain [nTPM]":"49.7","Brain RNA - pons [nTPM]":"55.9","Brain RNA - spinal cord [nTPM]":"35.8","Brain RNA - thalamus [nTPM]":"48.4","Brain RNA - white matter [nTPM]":"81.9","Single Cell Type RNA - Adipocytes [nTPM]":"43.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.6","Single Cell Type RNA - Astrocytes [nTPM]":"8.1","Single Cell Type RNA - B-cells [nTPM]":"69.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"3.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"41.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - dendritic cells [nTPM]":"79.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"25.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"41.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.6","Single Cell Type RNA - Endothelial cells [nTPM]":"19.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.1","Single Cell Type RNA - Erythroid cells [nTPM]":"28.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.4","Single Cell Type RNA - Fibroblasts [nTPM]":"4.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.0","Single Cell Type RNA - granulocytes [nTPM]":"40.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.6","Single Cell Type RNA - Hepatocytes [nTPM]":"2.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"67.0","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.0","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"66.2","Single Cell Type RNA - Langerhans cells [nTPM]":"29.9","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"9.6","Single Cell Type RNA - Macrophages [nTPM]":"44.7","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"62.0","Single Cell Type RNA - Muller glia cells [nTPM]":"7.5","Single Cell Type RNA - NK-cells [nTPM]":"85.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"50.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"40.5","Single Cell Type RNA - Paneth cells [nTPM]":"53.7","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"62.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"31.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.8","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"2.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.7","Single Cell Type RNA - T-cells [nTPM]":"83.7","Single Cell Type RNA - Theca cells [nTPM]":"2.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"30.3","Single Cell Type RNA - Urothelial cells [nTPM]":"37.4"},{"Gene":"TMC8","Gene synonym":["EVER2","EVIN2"],"Ensembl":"ENSG00000167895","Gene description":"Transmembrane channel like 8","Uniprot":["Q8IU68"],"Chromosome":"17","Position":"78130770-78142968","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"bone marrow":"91.8","intestine":"54.6","lymphoid tissue":"117.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"44.9","dendritic cells":"52.3","granulocytes":"41.2","Langerhans cells":"44.6","NK-cells":"85.5","T-cells":"68.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"46.3","HL-60":"63.0","HMC-1":"119.9","Karpas-707":"103.9","RPMI-8226":"66.6","U-266\/70":"49.3","U-937":"51.9"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047387","HPA054429"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA047387":null,"HPA054429":"AB_2682485"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.45e-6"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.19e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.96e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.8","Tissue RNA - adrenal gland [nTPM]":"3.0","Tissue RNA - amygdala [nTPM]":"3.6","Tissue RNA - appendix [nTPM]":"56.0","Tissue RNA - basal ganglia [nTPM]":"4.4","Tissue RNA - bone marrow [nTPM]":"91.8","Tissue RNA - breast [nTPM]":"3.7","Tissue RNA - cerebellum [nTPM]":"3.7","Tissue RNA - cerebral cortex [nTPM]":"5.1","Tissue RNA - cervix [nTPM]":"3.7","Tissue RNA - choroid plexus [nTPM]":"3.5","Tissue RNA - colon [nTPM]":"8.2","Tissue RNA - duodenum [nTPM]":"10.3","Tissue RNA - endometrium 1 [nTPM]":"2.5","Tissue RNA - epididymis [nTPM]":"0.7","Tissue RNA - esophagus [nTPM]":"4.8","Tissue RNA - fallopian tube [nTPM]":"4.0","Tissue RNA - gallbladder [nTPM]":"7.4","Tissue RNA - heart muscle [nTPM]":"2.7","Tissue RNA - hippocampal formation [nTPM]":"3.6","Tissue RNA - hypothalamus [nTPM]":"4.8","Tissue RNA - kidney [nTPM]":"5.2","Tissue RNA - liver [nTPM]":"7.1","Tissue RNA - lung [nTPM]":"18.4","Tissue RNA - lymph node [nTPM]":"100.5","Tissue RNA - medulla oblongata [nTPM]":"5.8","Tissue RNA - midbrain [nTPM]":"4.7","Tissue RNA - ovary [nTPM]":"1.3","Tissue RNA - pancreas [nTPM]":"2.0","Tissue RNA - parathyroid gland [nTPM]":"0.5","Tissue RNA - pituitary gland [nTPM]":"2.2","Tissue RNA - placenta [nTPM]":"3.9","Tissue RNA - pons [nTPM]":"5.6","Tissue RNA - prostate [nTPM]":"4.9","Tissue RNA - rectum [nTPM]":"4.5","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"5.8","Tissue RNA - seminal vesicle [nTPM]":"1.3","Tissue RNA - skeletal muscle [nTPM]":"1.8","Tissue RNA - skin 1 [nTPM]":"3.6","Tissue RNA - small intestine [nTPM]":"54.6","Tissue RNA - smooth muscle [nTPM]":"2.4","Tissue RNA - spinal cord [nTPM]":"5.0","Tissue RNA - spleen [nTPM]":"117.0","Tissue RNA - stomach 1 [nTPM]":"10.4","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"7.8","Tissue RNA - thymus [nTPM]":"60.1","Tissue RNA - thyroid gland [nTPM]":"6.4","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"46.7","Tissue RNA - urinary bladder [nTPM]":"6.4","Tissue RNA - vagina [nTPM]":"5.0","Tissue RNA - white matter [nTPM]":"7.2","Cell RNA - A-431 [nTPM]":"0.5","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"1.3","Cell RNA - Daudi [nTPM]":"46.3","Cell RNA - EFO-21 [nTPM]":"2.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"3.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"16.4","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.8","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"63.0","Cell RNA - HMC-1 [nTPM]":"119.9","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"22.1","Cell RNA - K-562 [nTPM]":"4.0","Cell RNA - Karpas-707 [nTPM]":"103.9","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.3","Cell RNA - MOLT-4 [nTPM]":"20.9","Cell RNA - NB-4 [nTPM]":"2.8","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"3.5","Cell RNA - PC-3 [nTPM]":"0.5","Cell RNA - REH [nTPM]":"1.4","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"66.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"2.2","Cell RNA - SK-MEL-30 [nTPM]":"0.6","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"6.9","Cell RNA - THP-1 [nTPM]":"12.7","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"49.3","Cell RNA - U-266\/84 [nTPM]":"2.0","Cell RNA - U-698 [nTPM]":"4.6","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"51.9","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"2.6","Blood RNA - classical monocyte [nTPM]":"2.0","Blood RNA - eosinophil [nTPM]":"6.6","Blood RNA - gdT-cell [nTPM]":"13.4","Blood RNA - intermediate monocyte [nTPM]":"3.4","Blood RNA - MAIT T-cell [nTPM]":"9.7","Blood RNA - memory B-cell [nTPM]":"5.5","Blood RNA - memory CD4 T-cell [nTPM]":"10.8","Blood RNA - memory CD8 T-cell [nTPM]":"13.3","Blood RNA - myeloid DC [nTPM]":"2.3","Blood RNA - naive B-cell [nTPM]":"4.8","Blood RNA - naive CD4 T-cell [nTPM]":"9.4","Blood RNA - naive CD8 T-cell [nTPM]":"8.6","Blood RNA - neutrophil [nTPM]":"3.3","Blood RNA - NK-cell [nTPM]":"7.5","Blood RNA - non-classical monocyte [nTPM]":"7.9","Blood RNA - plasmacytoid DC [nTPM]":"2.1","Blood RNA - T-reg [nTPM]":"6.5","Blood RNA - total PBMC [nTPM]":"5.5","Brain RNA - amygdala [nTPM]":"3.6","Brain RNA - basal ganglia [nTPM]":"4.4","Brain RNA - cerebellum [nTPM]":"3.7","Brain RNA - cerebral cortex [nTPM]":"5.1","Brain RNA - hippocampal formation [nTPM]":"3.6","Brain RNA - hypothalamus [nTPM]":"4.8","Brain RNA - medulla oblongata [nTPM]":"5.8","Brain RNA - midbrain [nTPM]":"4.7","Brain RNA - pons [nTPM]":"5.6","Brain RNA - spinal cord [nTPM]":"5.0","Brain RNA - thalamus [nTPM]":"7.8","Brain RNA - white matter [nTPM]":"7.2","Single Cell Type RNA - Adipocytes [nTPM]":"3.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.2","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"44.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"6.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"52.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.6","Single Cell Type RNA - Endothelial cells [nTPM]":"3.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"17.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.4","Single Cell Type RNA - Fibroblasts [nTPM]":"2.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.8","Single Cell Type RNA - granulocytes [nTPM]":"41.2","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.4","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"28.2","Single Cell Type RNA - Langerhans cells [nTPM]":"44.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"22.0","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"24.4","Single Cell Type RNA - monocytes [nTPM]":"30.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"85.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"3.6","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"20.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"68.6","Single Cell Type RNA - Theca cells [nTPM]":"2.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.0","Single Cell Type RNA - Urothelial cells [nTPM]":"10.7"},{"Gene":"TMCO1","Gene synonym":["HP10122","TMCC4"],"Ensembl":"ENSG00000143183","Gene description":"Transmembrane and coiled-coil domains 1","Uniprot":["Q9UM00"],"Chromosome":"1","Position":"165724293-165827755","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel"],"Disease involvement":["Disease variant","Glaucoma","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054768","HPA078775"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA054768":"AB_2682597","HPA078775":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.17e-7"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.21e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.25e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Tissue RNA - adipose tissue [nTPM]":"67.5","Tissue RNA - adrenal gland [nTPM]":"92.5","Tissue RNA - amygdala [nTPM]":"46.4","Tissue RNA - appendix [nTPM]":"51.6","Tissue RNA - basal ganglia [nTPM]":"50.2","Tissue RNA - bone marrow [nTPM]":"48.4","Tissue RNA - breast [nTPM]":"91.1","Tissue RNA - cerebellum [nTPM]":"53.8","Tissue RNA - cerebral cortex [nTPM]":"63.5","Tissue RNA - cervix [nTPM]":"74.0","Tissue RNA - choroid plexus [nTPM]":"72.2","Tissue RNA - colon [nTPM]":"127.0","Tissue RNA - duodenum [nTPM]":"115.7","Tissue RNA - endometrium 1 [nTPM]":"55.9","Tissue RNA - epididymis [nTPM]":"111.5","Tissue RNA - esophagus [nTPM]":"58.5","Tissue RNA - fallopian tube [nTPM]":"65.9","Tissue RNA - gallbladder [nTPM]":"80.1","Tissue RNA - heart muscle [nTPM]":"56.4","Tissue RNA - hippocampal formation [nTPM]":"46.4","Tissue RNA - hypothalamus [nTPM]":"55.6","Tissue RNA - kidney [nTPM]":"110.3","Tissue RNA - liver [nTPM]":"162.5","Tissue RNA - lung [nTPM]":"55.0","Tissue RNA - lymph node [nTPM]":"62.4","Tissue RNA - medulla oblongata [nTPM]":"54.1","Tissue RNA - midbrain [nTPM]":"55.5","Tissue RNA - ovary [nTPM]":"59.5","Tissue RNA - pancreas [nTPM]":"73.5","Tissue RNA - parathyroid gland [nTPM]":"143.6","Tissue RNA - pituitary gland [nTPM]":"33.8","Tissue RNA - placenta [nTPM]":"57.4","Tissue RNA - pons [nTPM]":"55.0","Tissue RNA - prostate [nTPM]":"79.6","Tissue RNA - rectum [nTPM]":"128.7","Tissue RNA - retina [nTPM]":"74.3","Tissue RNA - salivary gland [nTPM]":"77.8","Tissue RNA - seminal vesicle [nTPM]":"69.9","Tissue RNA - skeletal muscle [nTPM]":"48.7","Tissue RNA - skin 1 [nTPM]":"39.3","Tissue RNA - small intestine [nTPM]":"108.9","Tissue RNA - smooth muscle [nTPM]":"61.4","Tissue RNA - spinal cord [nTPM]":"56.6","Tissue RNA - spleen [nTPM]":"46.5","Tissue RNA - stomach 1 [nTPM]":"80.7","Tissue RNA - testis [nTPM]":"75.4","Tissue RNA - thalamus [nTPM]":"49.8","Tissue RNA - thymus [nTPM]":"89.3","Tissue RNA - thyroid gland [nTPM]":"103.8","Tissue RNA - tongue [nTPM]":"48.0","Tissue RNA - tonsil [nTPM]":"70.8","Tissue RNA - urinary bladder [nTPM]":"97.7","Tissue RNA - vagina [nTPM]":"29.1","Tissue RNA - white matter [nTPM]":"60.6","Cell RNA - A-431 [nTPM]":"158.4","Cell RNA - A549 [nTPM]":"172.1","Cell RNA - AF22 [nTPM]":"132.2","Cell RNA - AN3-CA [nTPM]":"77.9","Cell RNA - ASC diff [nTPM]":"243.9","Cell RNA - ASC TERT1 [nTPM]":"120.7","Cell RNA - BEWO [nTPM]":"126.9","Cell RNA - BJ [nTPM]":"259.4","Cell RNA - BJ hTERT+ [nTPM]":"191.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"156.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"162.1","Cell RNA - CACO-2 [nTPM]":"249.9","Cell RNA - CAPAN-2 [nTPM]":"229.2","Cell RNA - Daudi [nTPM]":"99.1","Cell RNA - EFO-21 [nTPM]":"267.4","Cell RNA - fHDF\/TERT166 [nTPM]":"195.9","Cell RNA - GAMG [nTPM]":"67.1","Cell RNA - HaCaT [nTPM]":"214.7","Cell RNA - HAP1 [nTPM]":"171.8","Cell RNA - HBEC3-KT [nTPM]":"140.3","Cell RNA - HBF TERT88 [nTPM]":"175.1","Cell RNA - HDLM-2 [nTPM]":"252.0","Cell RNA - HEK 293 [nTPM]":"164.2","Cell RNA - HEL [nTPM]":"121.1","Cell RNA - HeLa [nTPM]":"180.3","Cell RNA - Hep G2 [nTPM]":"158.7","Cell RNA - HHSteC [nTPM]":"195.1","Cell RNA - HL-60 [nTPM]":"216.6","Cell RNA - HMC-1 [nTPM]":"154.1","Cell RNA - HSkMC [nTPM]":"159.0","Cell RNA - hTCEpi [nTPM]":"173.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"179.5","Cell RNA - hTERT-HME1 [nTPM]":"142.6","Cell RNA - hTERT-RPE1 [nTPM]":"148.4","Cell RNA - HUVEC TERT2 [nTPM]":"117.1","Cell RNA - JURKAT [nTPM]":"122.6","Cell RNA - K-562 [nTPM]":"329.7","Cell RNA - Karpas-707 [nTPM]":"186.0","Cell RNA - LHCN-M2 [nTPM]":"227.3","Cell RNA - MCF7 [nTPM]":"123.1","Cell RNA - MOLT-4 [nTPM]":"172.1","Cell RNA - NB-4 [nTPM]":"160.6","Cell RNA - NTERA-2 [nTPM]":"169.4","Cell RNA - OE19 [nTPM]":"527.6","Cell RNA - PC-3 [nTPM]":"197.3","Cell RNA - REH [nTPM]":"125.0","Cell RNA - RH-30 [nTPM]":"143.4","Cell RNA - RPMI-8226 [nTPM]":"256.1","Cell RNA - RPTEC TERT1 [nTPM]":"204.7","Cell RNA - RT4 [nTPM]":"198.4","Cell RNA - SCLC-21H [nTPM]":"133.5","Cell RNA - SH-SY5Y [nTPM]":"235.4","Cell RNA - SiHa [nTPM]":"201.3","Cell RNA - SK-BR-3 [nTPM]":"209.2","Cell RNA - SK-MEL-30 [nTPM]":"170.9","Cell RNA - SuSa [nTPM]":"195.0","Cell RNA - T-47d [nTPM]":"277.1","Cell RNA - THP-1 [nTPM]":"275.7","Cell RNA - TIME [nTPM]":"121.5","Cell RNA - U-138 MG [nTPM]":"138.9","Cell RNA - U-2 OS [nTPM]":"116.5","Cell RNA - U-2197 [nTPM]":"123.8","Cell RNA - U-251 MG [nTPM]":"248.3","Cell RNA - U-266\/70 [nTPM]":"357.4","Cell RNA - U-266\/84 [nTPM]":"521.1","Cell RNA - U-698 [nTPM]":"346.5","Cell RNA - U-87 MG [nTPM]":"111.4","Cell RNA - U-937 [nTPM]":"139.7","Cell RNA - WM-115 [nTPM]":"187.4","Blood RNA - basophil [nTPM]":"213.3","Blood RNA - classical monocyte [nTPM]":"172.2","Blood RNA - eosinophil [nTPM]":"172.9","Blood RNA - gdT-cell [nTPM]":"159.7","Blood RNA - intermediate monocyte [nTPM]":"169.4","Blood RNA - MAIT T-cell [nTPM]":"170.4","Blood RNA - memory B-cell [nTPM]":"151.8","Blood RNA - memory CD4 T-cell [nTPM]":"168.7","Blood RNA - memory CD8 T-cell [nTPM]":"173.1","Blood RNA - myeloid DC [nTPM]":"135.5","Blood RNA - naive B-cell [nTPM]":"132.6","Blood RNA - naive CD4 T-cell [nTPM]":"134.3","Blood RNA - naive CD8 T-cell [nTPM]":"156.5","Blood RNA - neutrophil [nTPM]":"132.1","Blood RNA - NK-cell [nTPM]":"156.6","Blood RNA - non-classical monocyte [nTPM]":"201.7","Blood RNA - plasmacytoid DC [nTPM]":"243.8","Blood RNA - T-reg [nTPM]":"207.1","Blood RNA - total PBMC [nTPM]":"290.3","Brain RNA - amygdala [nTPM]":"46.4","Brain RNA - basal ganglia [nTPM]":"50.2","Brain RNA - cerebellum [nTPM]":"53.8","Brain RNA - cerebral cortex [nTPM]":"63.5","Brain RNA - hippocampal formation [nTPM]":"46.4","Brain RNA - hypothalamus [nTPM]":"55.6","Brain RNA - medulla oblongata [nTPM]":"54.1","Brain RNA - midbrain [nTPM]":"55.5","Brain RNA - pons [nTPM]":"55.0","Brain RNA - spinal cord [nTPM]":"56.6","Brain RNA - thalamus [nTPM]":"49.8","Brain RNA - white matter [nTPM]":"60.6","Single Cell Type RNA - Adipocytes [nTPM]":"124.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"96.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"70.7","Single Cell Type RNA - Astrocytes [nTPM]":"23.8","Single Cell Type RNA - B-cells [nTPM]":"95.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"84.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"89.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"264.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"75.1","Single Cell Type RNA - Bipolar cells [nTPM]":"79.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"142.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"135.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"62.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"224.4","Single Cell Type RNA - Club cells [nTPM]":"181.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"213.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"68.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"136.1","Single Cell Type RNA - dendritic cells [nTPM]":"138.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"371.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"43.0","Single Cell Type RNA - Ductal cells [nTPM]":"202.3","Single Cell Type RNA - Early spermatids [nTPM]":"82.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"131.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"147.9","Single Cell Type RNA - Endothelial cells [nTPM]":"92.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"88.6","Single Cell Type RNA - Erythroid cells [nTPM]":"75.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"20.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"191.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"148.4","Single Cell Type RNA - Fibroblasts [nTPM]":"113.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"64.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"154.7","Single Cell Type RNA - granulocytes [nTPM]":"76.5","Single Cell Type RNA - Granulosa cells [nTPM]":"71.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"106.7","Single Cell Type RNA - Hepatocytes [nTPM]":"326.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"140.9","Single Cell Type RNA - Horizontal cells [nTPM]":"75.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"137.0","Single Cell Type RNA - Ionocytes [nTPM]":"227.9","Single Cell Type RNA - Kupffer cells [nTPM]":"106.4","Single Cell Type RNA - Langerhans cells [nTPM]":"76.0","Single Cell Type RNA - Late spermatids [nTPM]":"151.6","Single Cell Type RNA - Leydig cells [nTPM]":"123.6","Single Cell Type RNA - Macrophages [nTPM]":"92.7","Single Cell Type RNA - Melanocytes [nTPM]":"99.6","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"78.9","Single Cell Type RNA - Muller glia cells [nTPM]":"236.7","Single Cell Type RNA - NK-cells [nTPM]":"152.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"25.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"23.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"227.0","Single Cell Type RNA - Paneth cells [nTPM]":"215.7","Single Cell Type RNA - Peritubular cells [nTPM]":"129.4","Single Cell Type RNA - Plasma cells [nTPM]":"153.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"73.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"290.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"151.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"175.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"75.9","Single Cell Type RNA - Sertoli cells [nTPM]":"124.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"67.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"101.7","Single Cell Type RNA - Spermatocytes [nTPM]":"232.1","Single Cell Type RNA - Spermatogonia [nTPM]":"87.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"89.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"92.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"111.4","Single Cell Type RNA - T-cells [nTPM]":"109.2","Single Cell Type RNA - Theca cells [nTPM]":"117.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"143.6","Single Cell Type RNA - Urothelial cells [nTPM]":"94.5"},{"Gene":"TMEM106B","Gene synonym":["FLJ11273","MGC33727"],"Ensembl":"ENSG00000106460","Gene description":"Transmembrane protein 106B","Uniprot":["Q9NUM4"],"Chromosome":"7","Position":"12211270-12243367","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Amyotrophic lateral sclerosis","Disease variant","Leukodystrophy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058342"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endosomes","Lysosomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":["Endosomes","Lysosomes"],"Subcellular additional location":null,"Antibody RRID":{"HPA058342":"AB_2683684"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.9","Tissue RNA - adrenal gland [nTPM]":"26.1","Tissue RNA - amygdala [nTPM]":"6.0","Tissue RNA - appendix [nTPM]":"7.1","Tissue RNA - basal ganglia [nTPM]":"8.5","Tissue RNA - bone marrow [nTPM]":"7.2","Tissue RNA - breast [nTPM]":"10.9","Tissue RNA - cerebellum [nTPM]":"10.7","Tissue RNA - cerebral cortex [nTPM]":"9.1","Tissue RNA - cervix [nTPM]":"13.1","Tissue RNA - choroid plexus [nTPM]":"7.6","Tissue RNA - colon [nTPM]":"12.6","Tissue RNA - duodenum [nTPM]":"8.6","Tissue RNA - endometrium 1 [nTPM]":"14.7","Tissue RNA - epididymis [nTPM]":"12.2","Tissue RNA - esophagus [nTPM]":"10.3","Tissue RNA - fallopian tube [nTPM]":"11.2","Tissue RNA - gallbladder [nTPM]":"9.1","Tissue RNA - heart muscle [nTPM]":"11.4","Tissue RNA - hippocampal formation [nTPM]":"6.3","Tissue RNA - hypothalamus [nTPM]":"7.0","Tissue RNA - kidney [nTPM]":"17.8","Tissue RNA - liver [nTPM]":"18.8","Tissue RNA - lung [nTPM]":"7.7","Tissue RNA - lymph node [nTPM]":"7.9","Tissue RNA - medulla oblongata [nTPM]":"7.4","Tissue RNA - midbrain [nTPM]":"7.4","Tissue RNA - ovary [nTPM]":"12.0","Tissue RNA - pancreas [nTPM]":"10.1","Tissue RNA - parathyroid gland [nTPM]":"12.7","Tissue RNA - pituitary gland [nTPM]":"9.9","Tissue RNA - placenta [nTPM]":"14.0","Tissue RNA - pons [nTPM]":"8.1","Tissue RNA - prostate [nTPM]":"14.6","Tissue RNA - rectum [nTPM]":"11.5","Tissue RNA - retina [nTPM]":"14.6","Tissue RNA - salivary gland [nTPM]":"13.1","Tissue RNA - seminal vesicle [nTPM]":"13.9","Tissue RNA - skeletal muscle [nTPM]":"14.7","Tissue RNA - skin 1 [nTPM]":"9.0","Tissue RNA - small intestine [nTPM]":"10.2","Tissue RNA - smooth muscle [nTPM]":"12.7","Tissue RNA - spinal cord [nTPM]":"10.5","Tissue RNA - spleen [nTPM]":"8.4","Tissue RNA - stomach 1 [nTPM]":"8.9","Tissue RNA - testis [nTPM]":"7.0","Tissue RNA - thalamus [nTPM]":"7.4","Tissue RNA - thymus [nTPM]":"6.7","Tissue RNA - thyroid gland [nTPM]":"16.0","Tissue RNA - tongue [nTPM]":"12.2","Tissue RNA - tonsil [nTPM]":"6.8","Tissue RNA - urinary bladder [nTPM]":"10.7","Tissue RNA - vagina [nTPM]":"10.2","Tissue RNA - white matter [nTPM]":"14.5","Cell RNA - A-431 [nTPM]":"13.9","Cell RNA - A549 [nTPM]":"26.3","Cell RNA - AF22 [nTPM]":"14.8","Cell RNA - AN3-CA [nTPM]":"24.2","Cell RNA - ASC diff [nTPM]":"26.3","Cell RNA - ASC TERT1 [nTPM]":"21.3","Cell RNA - BEWO [nTPM]":"11.5","Cell RNA - BJ [nTPM]":"19.7","Cell RNA - BJ hTERT+ [nTPM]":"33.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.7","Cell RNA - CACO-2 [nTPM]":"8.6","Cell RNA - CAPAN-2 [nTPM]":"42.1","Cell RNA - Daudi [nTPM]":"3.7","Cell RNA - EFO-21 [nTPM]":"21.2","Cell RNA - fHDF\/TERT166 [nTPM]":"23.5","Cell RNA - GAMG [nTPM]":"30.0","Cell RNA - HaCaT [nTPM]":"14.6","Cell RNA - HAP1 [nTPM]":"11.9","Cell RNA - HBEC3-KT [nTPM]":"12.5","Cell RNA - HBF TERT88 [nTPM]":"10.5","Cell RNA - HDLM-2 [nTPM]":"7.2","Cell RNA - HEK 293 [nTPM]":"11.5","Cell RNA - HEL [nTPM]":"5.5","Cell RNA - HeLa [nTPM]":"14.5","Cell RNA - Hep G2 [nTPM]":"8.3","Cell RNA - HHSteC [nTPM]":"20.8","Cell RNA - HL-60 [nTPM]":"20.5","Cell RNA - HMC-1 [nTPM]":"8.6","Cell RNA - HSkMC [nTPM]":"22.1","Cell RNA - hTCEpi [nTPM]":"14.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.9","Cell RNA - hTERT-HME1 [nTPM]":"19.2","Cell RNA - hTERT-RPE1 [nTPM]":"57.5","Cell RNA - HUVEC TERT2 [nTPM]":"16.0","Cell RNA - JURKAT [nTPM]":"10.2","Cell RNA - K-562 [nTPM]":"16.1","Cell RNA - Karpas-707 [nTPM]":"11.1","Cell RNA - LHCN-M2 [nTPM]":"14.9","Cell RNA - MCF7 [nTPM]":"4.4","Cell RNA - MOLT-4 [nTPM]":"3.9","Cell RNA - NB-4 [nTPM]":"8.6","Cell RNA - NTERA-2 [nTPM]":"17.4","Cell RNA - OE19 [nTPM]":"17.5","Cell RNA - PC-3 [nTPM]":"13.9","Cell RNA - REH [nTPM]":"11.1","Cell RNA - RH-30 [nTPM]":"10.9","Cell RNA - RPMI-8226 [nTPM]":"10.1","Cell RNA - RPTEC TERT1 [nTPM]":"23.5","Cell RNA - RT4 [nTPM]":"12.4","Cell RNA - SCLC-21H [nTPM]":"15.4","Cell RNA - SH-SY5Y [nTPM]":"21.4","Cell RNA - SiHa [nTPM]":"18.8","Cell RNA - SK-BR-3 [nTPM]":"15.4","Cell RNA - SK-MEL-30 [nTPM]":"16.7","Cell RNA - SuSa [nTPM]":"20.0","Cell RNA - T-47d [nTPM]":"13.9","Cell RNA - THP-1 [nTPM]":"10.0","Cell RNA - TIME [nTPM]":"18.9","Cell RNA - U-138 MG [nTPM]":"14.0","Cell RNA - U-2 OS [nTPM]":"20.3","Cell RNA - U-2197 [nTPM]":"14.1","Cell RNA - U-251 MG [nTPM]":"16.2","Cell RNA - U-266\/70 [nTPM]":"15.0","Cell RNA - U-266\/84 [nTPM]":"28.6","Cell RNA - U-698 [nTPM]":"5.9","Cell RNA - U-87 MG [nTPM]":"19.6","Cell RNA - U-937 [nTPM]":"6.7","Cell RNA - WM-115 [nTPM]":"35.2","Blood RNA - basophil [nTPM]":"11.6","Blood RNA - classical monocyte [nTPM]":"4.3","Blood RNA - eosinophil [nTPM]":"5.3","Blood RNA - gdT-cell [nTPM]":"9.1","Blood RNA - intermediate monocyte [nTPM]":"5.2","Blood RNA - MAIT T-cell [nTPM]":"12.8","Blood RNA - memory B-cell [nTPM]":"6.1","Blood RNA - memory CD4 T-cell [nTPM]":"10.6","Blood RNA - memory CD8 T-cell [nTPM]":"10.6","Blood RNA - myeloid DC [nTPM]":"2.9","Blood RNA - naive B-cell [nTPM]":"7.8","Blood RNA - naive CD4 T-cell [nTPM]":"17.3","Blood RNA - naive CD8 T-cell [nTPM]":"13.2","Blood RNA - neutrophil [nTPM]":"2.8","Blood RNA - NK-cell [nTPM]":"14.4","Blood RNA - non-classical monocyte [nTPM]":"7.9","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"10.3","Blood RNA - total PBMC [nTPM]":"6.8","Brain RNA - amygdala [nTPM]":"6.0","Brain RNA - basal ganglia [nTPM]":"8.5","Brain RNA - cerebellum [nTPM]":"10.7","Brain RNA - cerebral cortex [nTPM]":"9.1","Brain RNA - hippocampal formation [nTPM]":"6.3","Brain RNA - hypothalamus [nTPM]":"7.0","Brain RNA - medulla oblongata [nTPM]":"7.4","Brain RNA - midbrain [nTPM]":"7.4","Brain RNA - pons [nTPM]":"8.1","Brain RNA - spinal cord [nTPM]":"10.5","Brain RNA - thalamus [nTPM]":"7.4","Brain RNA - white matter [nTPM]":"14.5","Single Cell Type RNA - Adipocytes [nTPM]":"45.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"73.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"40.3","Single Cell Type RNA - Astrocytes [nTPM]":"41.1","Single Cell Type RNA - B-cells [nTPM]":"34.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"36.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"42.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"38.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"62.6","Single Cell Type RNA - Bipolar cells [nTPM]":"55.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"46.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"46.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"49.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"66.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"54.0","Single Cell Type RNA - dendritic cells [nTPM]":"18.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"53.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"115.4","Single Cell Type RNA - Early spermatids [nTPM]":"5.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"29.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"56.3","Single Cell Type RNA - Endothelial cells [nTPM]":"34.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"57.6","Single Cell Type RNA - Erythroid cells [nTPM]":"24.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"60.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"58.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"36.0","Single Cell Type RNA - Fibroblasts [nTPM]":"65.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"36.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"37.8","Single Cell Type RNA - granulocytes [nTPM]":"14.5","Single Cell Type RNA - Granulosa cells [nTPM]":"53.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"41.7","Single Cell Type RNA - Hepatocytes [nTPM]":"85.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"33.3","Single Cell Type RNA - Horizontal cells [nTPM]":"65.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"78.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"37.9","Single Cell Type RNA - Ionocytes [nTPM]":"57.0","Single Cell Type RNA - Kupffer cells [nTPM]":"29.2","Single Cell Type RNA - Langerhans cells [nTPM]":"23.9","Single Cell Type RNA - Late spermatids [nTPM]":"4.3","Single Cell Type RNA - Leydig cells [nTPM]":"49.0","Single Cell Type RNA - Macrophages [nTPM]":"23.9","Single Cell Type RNA - Melanocytes [nTPM]":"37.4","Single Cell Type RNA - Microglial cells [nTPM]":"28.1","Single Cell Type RNA - monocytes [nTPM]":"19.1","Single Cell Type RNA - Muller glia cells [nTPM]":"95.2","Single Cell Type RNA - NK-cells [nTPM]":"39.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"66.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"82.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"75.3","Single Cell Type RNA - Paneth cells [nTPM]":"53.4","Single Cell Type RNA - Peritubular cells [nTPM]":"60.9","Single Cell Type RNA - Plasma cells [nTPM]":"39.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"85.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"57.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"67.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"47.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"51.8","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"49.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"41.6","Single Cell Type RNA - Spermatocytes [nTPM]":"40.1","Single Cell Type RNA - Spermatogonia [nTPM]":"31.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"56.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"43.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"135.6","Single Cell Type RNA - T-cells [nTPM]":"41.1","Single Cell Type RNA - Theca cells [nTPM]":"70.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"47.2","Single Cell Type RNA - Urothelial cells [nTPM]":"81.9"},{"Gene":"TMEM126A","Gene synonym":["DKFZp586C1924","OPA7"],"Ensembl":"ENSG00000171202","Gene description":"Transmembrane protein 126A","Uniprot":["Q9H061"],"Chromosome":"11","Position":"85647967-85656547","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046648"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA046648":"AB_2679737"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.60e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Tissue RNA - adipose tissue [nTPM]":"31.9","Tissue RNA - adrenal gland [nTPM]":"28.0","Tissue RNA - amygdala [nTPM]":"40.3","Tissue RNA - appendix [nTPM]":"23.1","Tissue RNA - basal ganglia [nTPM]":"41.5","Tissue RNA - bone marrow [nTPM]":"43.8","Tissue RNA - breast [nTPM]":"33.5","Tissue RNA - cerebellum [nTPM]":"41.4","Tissue RNA - cerebral cortex [nTPM]":"52.3","Tissue RNA - cervix [nTPM]":"21.8","Tissue RNA - choroid plexus [nTPM]":"39.5","Tissue RNA - colon [nTPM]":"28.0","Tissue RNA - duodenum [nTPM]":"32.6","Tissue RNA - endometrium 1 [nTPM]":"20.0","Tissue RNA - epididymis [nTPM]":"31.2","Tissue RNA - esophagus [nTPM]":"27.2","Tissue RNA - fallopian tube [nTPM]":"19.8","Tissue RNA - gallbladder [nTPM]":"19.9","Tissue RNA - heart muscle [nTPM]":"82.1","Tissue RNA - hippocampal formation [nTPM]":"41.4","Tissue RNA - hypothalamus [nTPM]":"42.3","Tissue RNA - kidney [nTPM]":"33.1","Tissue RNA - liver [nTPM]":"49.0","Tissue RNA - lung [nTPM]":"20.5","Tissue RNA - lymph node [nTPM]":"27.3","Tissue RNA - medulla oblongata [nTPM]":"40.7","Tissue RNA - midbrain [nTPM]":"40.6","Tissue RNA - ovary [nTPM]":"21.0","Tissue RNA - pancreas [nTPM]":"33.9","Tissue RNA - parathyroid gland [nTPM]":"26.3","Tissue RNA - pituitary gland [nTPM]":"22.2","Tissue RNA - placenta [nTPM]":"22.8","Tissue RNA - pons [nTPM]":"41.5","Tissue RNA - prostate [nTPM]":"23.5","Tissue RNA - rectum [nTPM]":"29.3","Tissue RNA - retina [nTPM]":"23.9","Tissue RNA - salivary gland [nTPM]":"31.3","Tissue RNA - seminal vesicle [nTPM]":"19.5","Tissue RNA - skeletal muscle [nTPM]":"81.6","Tissue RNA - skin 1 [nTPM]":"19.4","Tissue RNA - small intestine [nTPM]":"26.0","Tissue RNA - smooth muscle [nTPM]":"27.6","Tissue RNA - spinal cord [nTPM]":"41.1","Tissue RNA - spleen [nTPM]":"21.0","Tissue RNA - stomach 1 [nTPM]":"32.8","Tissue RNA - testis [nTPM]":"38.5","Tissue RNA - thalamus [nTPM]":"41.4","Tissue RNA - thymus [nTPM]":"24.2","Tissue RNA - thyroid gland [nTPM]":"26.6","Tissue RNA - tongue [nTPM]":"98.7","Tissue RNA - tonsil [nTPM]":"27.8","Tissue RNA - urinary bladder [nTPM]":"30.5","Tissue RNA - vagina [nTPM]":"20.1","Tissue RNA - white matter [nTPM]":"42.4","Cell RNA - A-431 [nTPM]":"46.7","Cell RNA - A549 [nTPM]":"53.2","Cell RNA - AF22 [nTPM]":"50.9","Cell RNA - AN3-CA [nTPM]":"33.0","Cell RNA - ASC diff [nTPM]":"67.2","Cell RNA - ASC TERT1 [nTPM]":"66.7","Cell RNA - BEWO [nTPM]":"38.0","Cell RNA - BJ [nTPM]":"55.9","Cell RNA - BJ hTERT+ [nTPM]":"60.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"82.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"77.6","Cell RNA - CACO-2 [nTPM]":"65.9","Cell RNA - CAPAN-2 [nTPM]":"67.5","Cell RNA - Daudi [nTPM]":"25.4","Cell RNA - EFO-21 [nTPM]":"61.3","Cell RNA - fHDF\/TERT166 [nTPM]":"69.2","Cell RNA - GAMG [nTPM]":"32.0","Cell RNA - HaCaT [nTPM]":"48.9","Cell RNA - HAP1 [nTPM]":"53.8","Cell RNA - HBEC3-KT [nTPM]":"59.5","Cell RNA - HBF TERT88 [nTPM]":"70.7","Cell RNA - HDLM-2 [nTPM]":"72.5","Cell RNA - HEK 293 [nTPM]":"31.0","Cell RNA - HEL [nTPM]":"72.5","Cell RNA - HeLa [nTPM]":"56.9","Cell RNA - Hep G2 [nTPM]":"73.7","Cell RNA - HHSteC [nTPM]":"82.4","Cell RNA - HL-60 [nTPM]":"89.0","Cell RNA - HMC-1 [nTPM]":"54.8","Cell RNA - HSkMC [nTPM]":"58.0","Cell RNA - hTCEpi [nTPM]":"65.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"73.1","Cell RNA - hTERT-HME1 [nTPM]":"78.0","Cell RNA - hTERT-RPE1 [nTPM]":"43.5","Cell RNA - HUVEC TERT2 [nTPM]":"71.6","Cell RNA - JURKAT [nTPM]":"72.2","Cell RNA - K-562 [nTPM]":"51.1","Cell RNA - Karpas-707 [nTPM]":"39.0","Cell RNA - LHCN-M2 [nTPM]":"86.2","Cell RNA - MCF7 [nTPM]":"57.5","Cell RNA - MOLT-4 [nTPM]":"48.6","Cell RNA - NB-4 [nTPM]":"112.3","Cell RNA - NTERA-2 [nTPM]":"48.1","Cell RNA - OE19 [nTPM]":"175.1","Cell RNA - PC-3 [nTPM]":"68.4","Cell RNA - REH [nTPM]":"48.3","Cell RNA - RH-30 [nTPM]":"49.5","Cell RNA - RPMI-8226 [nTPM]":"79.2","Cell RNA - RPTEC TERT1 [nTPM]":"54.5","Cell RNA - RT4 [nTPM]":"57.0","Cell RNA - SCLC-21H [nTPM]":"34.3","Cell RNA - SH-SY5Y [nTPM]":"34.7","Cell RNA - SiHa [nTPM]":"49.4","Cell RNA - SK-BR-3 [nTPM]":"72.9","Cell RNA - SK-MEL-30 [nTPM]":"44.7","Cell RNA - SuSa [nTPM]":"44.5","Cell RNA - T-47d [nTPM]":"88.1","Cell RNA - THP-1 [nTPM]":"64.4","Cell RNA - TIME [nTPM]":"42.8","Cell RNA - U-138 MG [nTPM]":"70.4","Cell RNA - U-2 OS [nTPM]":"52.7","Cell RNA - U-2197 [nTPM]":"134.6","Cell RNA - U-251 MG [nTPM]":"65.3","Cell RNA - U-266\/70 [nTPM]":"27.5","Cell RNA - U-266\/84 [nTPM]":"54.4","Cell RNA - U-698 [nTPM]":"70.4","Cell RNA - U-87 MG [nTPM]":"37.0","Cell RNA - U-937 [nTPM]":"63.6","Cell RNA - WM-115 [nTPM]":"85.2","Blood RNA - basophil [nTPM]":"6.6","Blood RNA - classical monocyte [nTPM]":"23.9","Blood RNA - eosinophil [nTPM]":"11.6","Blood RNA - gdT-cell [nTPM]":"21.2","Blood RNA - intermediate monocyte [nTPM]":"28.1","Blood RNA - MAIT T-cell [nTPM]":"26.0","Blood RNA - memory B-cell [nTPM]":"29.8","Blood RNA - memory CD4 T-cell [nTPM]":"26.4","Blood RNA - memory CD8 T-cell [nTPM]":"23.8","Blood RNA - myeloid DC [nTPM]":"32.9","Blood RNA - naive B-cell [nTPM]":"27.3","Blood RNA - naive CD4 T-cell [nTPM]":"24.4","Blood RNA - naive CD8 T-cell [nTPM]":"24.1","Blood RNA - neutrophil [nTPM]":"1.9","Blood RNA - NK-cell [nTPM]":"15.1","Blood RNA - non-classical monocyte [nTPM]":"23.4","Blood RNA - plasmacytoid DC [nTPM]":"24.7","Blood RNA - T-reg [nTPM]":"26.4","Blood RNA - total PBMC [nTPM]":"18.7","Brain RNA - amygdala [nTPM]":"40.3","Brain RNA - basal ganglia [nTPM]":"41.5","Brain RNA - cerebellum [nTPM]":"41.4","Brain RNA - cerebral cortex [nTPM]":"52.3","Brain RNA - hippocampal formation [nTPM]":"41.4","Brain RNA - hypothalamus [nTPM]":"42.3","Brain RNA - medulla oblongata [nTPM]":"40.7","Brain RNA - midbrain [nTPM]":"40.6","Brain RNA - pons [nTPM]":"41.5","Brain RNA - spinal cord [nTPM]":"41.1","Brain RNA - thalamus [nTPM]":"41.4","Brain RNA - white matter [nTPM]":"42.4","Single Cell Type RNA - Adipocytes [nTPM]":"40.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"24.3","Single Cell Type RNA - Astrocytes [nTPM]":"12.7","Single Cell Type RNA - B-cells [nTPM]":"39.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"31.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"55.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"87.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"29.6","Single Cell Type RNA - Bipolar cells [nTPM]":"14.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"45.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"62.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"110.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"28.6","Single Cell Type RNA - Club cells [nTPM]":"57.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"67.8","Single Cell Type RNA - dendritic cells [nTPM]":"38.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"146.8","Single Cell Type RNA - Ductal cells [nTPM]":"51.0","Single Cell Type RNA - Early spermatids [nTPM]":"147.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"26.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"32.8","Single Cell Type RNA - Endothelial cells [nTPM]":"36.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.7","Single Cell Type RNA - Erythroid cells [nTPM]":"46.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"93.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"73.3","Single Cell Type RNA - Fibroblasts [nTPM]":"40.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.2","Single Cell Type RNA - granulocytes [nTPM]":"37.4","Single Cell Type RNA - Granulosa cells [nTPM]":"33.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.7","Single Cell Type RNA - Hepatocytes [nTPM]":"68.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"94.6","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"46.6","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"54.4","Single Cell Type RNA - Langerhans cells [nTPM]":"43.3","Single Cell Type RNA - Late spermatids [nTPM]":"80.6","Single Cell Type RNA - Leydig cells [nTPM]":"29.5","Single Cell Type RNA - Macrophages [nTPM]":"48.4","Single Cell Type RNA - Melanocytes [nTPM]":"33.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"66.3","Single Cell Type RNA - Muller glia cells [nTPM]":"35.1","Single Cell Type RNA - NK-cells [nTPM]":"38.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"64.5","Single Cell Type RNA - Paneth cells [nTPM]":"34.8","Single Cell Type RNA - Peritubular cells [nTPM]":"26.7","Single Cell Type RNA - Plasma cells [nTPM]":"45.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"73.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"61.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"109.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"39.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.9","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"40.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"40.9","Single Cell Type RNA - Spermatocytes [nTPM]":"119.0","Single Cell Type RNA - Spermatogonia [nTPM]":"57.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"49.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"42.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"52.9","Single Cell Type RNA - T-cells [nTPM]":"42.1","Single Cell Type RNA - Theca cells [nTPM]":"42.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"57.1","Single Cell Type RNA - Urothelial cells [nTPM]":"71.2"},{"Gene":"TMEM126B","Gene synonym":["HT007"],"Ensembl":"ENSG00000171204","Gene description":"Transmembrane protein 126B","Uniprot":["Q8IUX1"],"Chromosome":"11","Position":"85628573-85636539","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014480","HPA019186"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA014480":"AB_1858083","HPA019186":"AB_1858084"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Tissue RNA - adipose tissue [nTPM]":"16.1","Tissue RNA - adrenal gland [nTPM]":"16.7","Tissue RNA - amygdala [nTPM]":"29.2","Tissue RNA - appendix [nTPM]":"13.0","Tissue RNA - basal ganglia [nTPM]":"29.4","Tissue RNA - bone marrow [nTPM]":"6.5","Tissue RNA - breast [nTPM]":"19.3","Tissue RNA - cerebellum [nTPM]":"28.9","Tissue RNA - cerebral cortex [nTPM]":"38.9","Tissue RNA - cervix [nTPM]":"18.2","Tissue RNA - choroid plexus [nTPM]":"25.9","Tissue RNA - colon [nTPM]":"21.4","Tissue RNA - duodenum [nTPM]":"19.6","Tissue RNA - endometrium 1 [nTPM]":"19.3","Tissue RNA - epididymis [nTPM]":"30.7","Tissue RNA - esophagus [nTPM]":"14.3","Tissue RNA - fallopian tube [nTPM]":"15.8","Tissue RNA - gallbladder [nTPM]":"17.3","Tissue RNA - heart muscle [nTPM]":"24.7","Tissue RNA - hippocampal formation [nTPM]":"30.4","Tissue RNA - hypothalamus [nTPM]":"31.7","Tissue RNA - kidney [nTPM]":"15.3","Tissue RNA - liver [nTPM]":"17.2","Tissue RNA - lung [nTPM]":"15.8","Tissue RNA - lymph node [nTPM]":"18.7","Tissue RNA - medulla oblongata [nTPM]":"29.7","Tissue RNA - midbrain [nTPM]":"30.0","Tissue RNA - ovary [nTPM]":"16.4","Tissue RNA - pancreas [nTPM]":"15.9","Tissue RNA - parathyroid gland [nTPM]":"11.0","Tissue RNA - pituitary gland [nTPM]":"20.8","Tissue RNA - placenta [nTPM]":"13.3","Tissue RNA - pons [nTPM]":"30.9","Tissue RNA - prostate [nTPM]":"17.0","Tissue RNA - rectum [nTPM]":"17.6","Tissue RNA - retina [nTPM]":"18.6","Tissue RNA - salivary gland [nTPM]":"15.7","Tissue RNA - seminal vesicle [nTPM]":"14.1","Tissue RNA - skeletal muscle [nTPM]":"16.2","Tissue RNA - skin 1 [nTPM]":"13.8","Tissue RNA - small intestine [nTPM]":"19.8","Tissue RNA - smooth muscle [nTPM]":"21.4","Tissue RNA - spinal cord [nTPM]":"30.1","Tissue RNA - spleen [nTPM]":"16.5","Tissue RNA - stomach 1 [nTPM]":"17.6","Tissue RNA - testis [nTPM]":"10.9","Tissue RNA - thalamus [nTPM]":"30.2","Tissue RNA - thymus [nTPM]":"16.0","Tissue RNA - thyroid gland [nTPM]":"16.8","Tissue RNA - tongue [nTPM]":"20.1","Tissue RNA - tonsil [nTPM]":"17.5","Tissue RNA - urinary bladder [nTPM]":"18.6","Tissue RNA - vagina [nTPM]":"14.8","Tissue RNA - white matter [nTPM]":"32.3","Cell RNA - A-431 [nTPM]":"37.9","Cell RNA - A549 [nTPM]":"29.8","Cell RNA - AF22 [nTPM]":"33.1","Cell RNA - AN3-CA [nTPM]":"16.0","Cell RNA - ASC diff [nTPM]":"60.2","Cell RNA - ASC TERT1 [nTPM]":"49.6","Cell RNA - BEWO [nTPM]":"10.6","Cell RNA - BJ [nTPM]":"33.1","Cell RNA - BJ hTERT+ [nTPM]":"36.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"25.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"38.1","Cell RNA - CACO-2 [nTPM]":"84.8","Cell RNA - CAPAN-2 [nTPM]":"37.1","Cell RNA - Daudi [nTPM]":"39.9","Cell RNA - EFO-21 [nTPM]":"72.2","Cell RNA - fHDF\/TERT166 [nTPM]":"27.1","Cell RNA - GAMG [nTPM]":"28.6","Cell RNA - HaCaT [nTPM]":"45.0","Cell RNA - HAP1 [nTPM]":"53.2","Cell RNA - HBEC3-KT [nTPM]":"33.0","Cell RNA - HBF TERT88 [nTPM]":"23.8","Cell RNA - HDLM-2 [nTPM]":"56.5","Cell RNA - HEK 293 [nTPM]":"49.7","Cell RNA - HEL [nTPM]":"30.1","Cell RNA - HeLa [nTPM]":"49.1","Cell RNA - Hep G2 [nTPM]":"36.1","Cell RNA - HHSteC [nTPM]":"35.6","Cell RNA - HL-60 [nTPM]":"75.4","Cell RNA - HMC-1 [nTPM]":"34.7","Cell RNA - HSkMC [nTPM]":"37.9","Cell RNA - hTCEpi [nTPM]":"38.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"38.6","Cell RNA - hTERT-HME1 [nTPM]":"47.0","Cell RNA - hTERT-RPE1 [nTPM]":"41.1","Cell RNA - HUVEC TERT2 [nTPM]":"38.6","Cell RNA - JURKAT [nTPM]":"49.5","Cell RNA - K-562 [nTPM]":"72.5","Cell RNA - Karpas-707 [nTPM]":"31.2","Cell RNA - LHCN-M2 [nTPM]":"58.8","Cell RNA - MCF7 [nTPM]":"47.9","Cell RNA - MOLT-4 [nTPM]":"29.4","Cell RNA - NB-4 [nTPM]":"91.3","Cell RNA - NTERA-2 [nTPM]":"36.1","Cell RNA - OE19 [nTPM]":"129.6","Cell RNA - PC-3 [nTPM]":"50.1","Cell RNA - REH [nTPM]":"25.0","Cell RNA - RH-30 [nTPM]":"25.4","Cell RNA - RPMI-8226 [nTPM]":"33.6","Cell RNA - RPTEC TERT1 [nTPM]":"49.5","Cell RNA - RT4 [nTPM]":"42.1","Cell RNA - SCLC-21H [nTPM]":"30.8","Cell RNA - SH-SY5Y [nTPM]":"19.1","Cell RNA - SiHa [nTPM]":"31.2","Cell RNA - SK-BR-3 [nTPM]":"24.9","Cell RNA - SK-MEL-30 [nTPM]":"31.9","Cell RNA - SuSa [nTPM]":"42.5","Cell RNA - T-47d [nTPM]":"50.1","Cell RNA - THP-1 [nTPM]":"45.4","Cell RNA - TIME [nTPM]":"20.5","Cell RNA - U-138 MG [nTPM]":"38.2","Cell RNA - U-2 OS [nTPM]":"26.5","Cell RNA - U-2197 [nTPM]":"96.9","Cell RNA - U-251 MG [nTPM]":"35.4","Cell RNA - U-266\/70 [nTPM]":"14.6","Cell RNA - U-266\/84 [nTPM]":"91.1","Cell RNA - U-698 [nTPM]":"47.7","Cell RNA - U-87 MG [nTPM]":"19.4","Cell RNA - U-937 [nTPM]":"60.4","Cell RNA - WM-115 [nTPM]":"20.6","Blood RNA - basophil [nTPM]":"21.5","Blood RNA - classical monocyte [nTPM]":"15.6","Blood RNA - eosinophil [nTPM]":"7.9","Blood RNA - gdT-cell [nTPM]":"19.0","Blood RNA - intermediate monocyte [nTPM]":"18.2","Blood RNA - MAIT T-cell [nTPM]":"24.8","Blood RNA - memory B-cell [nTPM]":"18.3","Blood RNA - memory CD4 T-cell [nTPM]":"23.4","Blood RNA - memory CD8 T-cell [nTPM]":"23.5","Blood RNA - myeloid DC [nTPM]":"20.1","Blood RNA - naive B-cell [nTPM]":"17.7","Blood RNA - naive CD4 T-cell [nTPM]":"23.3","Blood RNA - naive CD8 T-cell [nTPM]":"23.4","Blood RNA - neutrophil [nTPM]":"5.9","Blood RNA - NK-cell [nTPM]":"23.4","Blood RNA - non-classical monocyte [nTPM]":"14.5","Blood RNA - plasmacytoid DC [nTPM]":"18.4","Blood RNA - T-reg [nTPM]":"25.9","Blood RNA - total PBMC [nTPM]":"15.9","Brain RNA - amygdala [nTPM]":"29.2","Brain RNA - basal ganglia [nTPM]":"29.4","Brain RNA - cerebellum [nTPM]":"28.9","Brain RNA - cerebral cortex [nTPM]":"38.9","Brain RNA - hippocampal formation [nTPM]":"30.4","Brain RNA - hypothalamus [nTPM]":"31.7","Brain RNA - medulla oblongata [nTPM]":"29.7","Brain RNA - midbrain [nTPM]":"30.0","Brain RNA - pons [nTPM]":"30.9","Brain RNA - spinal cord [nTPM]":"30.1","Brain RNA - thalamus [nTPM]":"30.2","Brain RNA - white matter [nTPM]":"32.3","Single Cell Type RNA - Adipocytes [nTPM]":"44.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"40.7","Single Cell Type RNA - Astrocytes [nTPM]":"16.6","Single Cell Type RNA - B-cells [nTPM]":"34.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"26.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"80.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.8","Single Cell Type RNA - Bipolar cells [nTPM]":"32.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"36.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"31.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"87.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"54.3","Single Cell Type RNA - Club cells [nTPM]":"57.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"41.0","Single Cell Type RNA - dendritic cells [nTPM]":"54.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"33.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"168.3","Single Cell Type RNA - Ductal cells [nTPM]":"76.0","Single Cell Type RNA - Early spermatids [nTPM]":"5.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"39.2","Single Cell Type RNA - Endothelial cells [nTPM]":"46.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"34.6","Single Cell Type RNA - Erythroid cells [nTPM]":"34.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"49.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"54.5","Single Cell Type RNA - Fibroblasts [nTPM]":"45.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.8","Single Cell Type RNA - granulocytes [nTPM]":"42.5","Single Cell Type RNA - Granulosa cells [nTPM]":"27.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"42.5","Single Cell Type RNA - Hepatocytes [nTPM]":"43.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"84.1","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"41.3","Single Cell Type RNA - Ionocytes [nTPM]":"81.4","Single Cell Type RNA - Kupffer cells [nTPM]":"47.4","Single Cell Type RNA - Langerhans cells [nTPM]":"44.6","Single Cell Type RNA - Late spermatids [nTPM]":"8.3","Single Cell Type RNA - Leydig cells [nTPM]":"66.5","Single Cell Type RNA - Macrophages [nTPM]":"43.5","Single Cell Type RNA - Melanocytes [nTPM]":"72.9","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"48.8","Single Cell Type RNA - Muller glia cells [nTPM]":"79.0","Single Cell Type RNA - NK-cells [nTPM]":"80.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"29.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"51.5","Single Cell Type RNA - Paneth cells [nTPM]":"52.8","Single Cell Type RNA - Peritubular cells [nTPM]":"88.4","Single Cell Type RNA - Plasma cells [nTPM]":"22.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"35.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"56.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"162.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"51.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"31.2","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"43.8","Single Cell Type RNA - Spermatocytes [nTPM]":"34.4","Single Cell Type RNA - Spermatogonia [nTPM]":"46.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"36.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"25.2","Single Cell Type RNA - T-cells [nTPM]":"49.7","Single Cell Type RNA - Theca cells [nTPM]":"45.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"52.0","Single Cell Type RNA - Urothelial cells [nTPM]":"45.4"},{"Gene":"TMEM132E","Gene synonym":["DFNB99"],"Ensembl":"ENSG00000181291","Gene description":"Transmembrane protein 132E","Uniprot":["Q6IEE7"],"Chromosome":"17","Position":"34579487-34639318","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"17.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"4.1","Inhibitory neurons":"6.4","Oligodendrocyte precursor cells":"13.0","Proximal tubular cells":"11.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"7.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"RPMI-8226":"37.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070608"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000","Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":["Nuclear bodies","Cytosol"],"Antibody RRID":{"HPA070608":"AB_2686286"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.55e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"4.6","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"3.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"6.1","Tissue RNA - cerebral cortex [nTPM]":"6.4","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"1.2","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"2.6","Tissue RNA - hypothalamus [nTPM]":"6.2","Tissue RNA - kidney [nTPM]":"3.6","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"17.9","Tissue RNA - midbrain [nTPM]":"5.1","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"10.2","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.7","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"8.7","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"1.9","Tissue RNA - thalamus [nTPM]":"6.5","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"11.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"1.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.1","Cell RNA - HEL [nTPM]":"4.3","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"3.6","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"37.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.6","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.6","Brain RNA - basal ganglia [nTPM]":"3.0","Brain RNA - cerebellum [nTPM]":"6.1","Brain RNA - cerebral cortex [nTPM]":"6.4","Brain RNA - hippocampal formation [nTPM]":"2.6","Brain RNA - hypothalamus [nTPM]":"6.2","Brain RNA - medulla oblongata [nTPM]":"17.9","Brain RNA - midbrain [nTPM]":"5.1","Brain RNA - pons [nTPM]":"10.2","Brain RNA - spinal cord [nTPM]":"8.7","Brain RNA - thalamus [nTPM]":"6.5","Brain RNA - white matter [nTPM]":"11.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"2.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"1.2","Single Cell Type RNA - Spermatogonia [nTPM]":"2.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"TMEM165","Gene synonym":["GDT1","TMPT27","TPARL"],"Ensembl":"ENSG00000134851","Gene description":"Transmembrane protein 165","Uniprot":["Q9HC07"],"Chromosome":"4","Position":"55395957-55453397","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"1021.6","Urothelial cells":"601.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038299","HPA062424"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA038299":"AB_10675793","HPA062424":"AB_2732682"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.08e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.00e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.18e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Tissue RNA - adipose tissue [nTPM]":"53.4","Tissue RNA - adrenal gland [nTPM]":"61.3","Tissue RNA - amygdala [nTPM]":"39.2","Tissue RNA - appendix [nTPM]":"42.6","Tissue RNA - basal ganglia [nTPM]":"75.1","Tissue RNA - bone marrow [nTPM]":"11.3","Tissue RNA - breast [nTPM]":"35.2","Tissue RNA - cerebellum [nTPM]":"62.0","Tissue RNA - cerebral cortex [nTPM]":"70.8","Tissue RNA - cervix [nTPM]":"45.9","Tissue RNA - choroid plexus [nTPM]":"36.0","Tissue RNA - colon [nTPM]":"32.4","Tissue RNA - duodenum [nTPM]":"32.0","Tissue RNA - endometrium 1 [nTPM]":"34.0","Tissue RNA - epididymis [nTPM]":"31.1","Tissue RNA - esophagus [nTPM]":"55.8","Tissue RNA - fallopian tube [nTPM]":"31.6","Tissue RNA - gallbladder [nTPM]":"46.0","Tissue RNA - heart muscle [nTPM]":"37.3","Tissue RNA - hippocampal formation [nTPM]":"40.8","Tissue RNA - hypothalamus [nTPM]":"51.1","Tissue RNA - kidney [nTPM]":"41.6","Tissue RNA - liver [nTPM]":"19.3","Tissue RNA - lung [nTPM]":"52.7","Tissue RNA - lymph node [nTPM]":"32.6","Tissue RNA - medulla oblongata [nTPM]":"84.8","Tissue RNA - midbrain [nTPM]":"72.0","Tissue RNA - ovary [nTPM]":"22.3","Tissue RNA - pancreas [nTPM]":"40.1","Tissue RNA - parathyroid gland [nTPM]":"32.3","Tissue RNA - pituitary gland [nTPM]":"24.0","Tissue RNA - placenta [nTPM]":"60.5","Tissue RNA - pons [nTPM]":"78.9","Tissue RNA - prostate [nTPM]":"37.8","Tissue RNA - rectum [nTPM]":"33.3","Tissue RNA - retina [nTPM]":"15.0","Tissue RNA - salivary gland [nTPM]":"40.4","Tissue RNA - seminal vesicle [nTPM]":"30.6","Tissue RNA - skeletal muscle [nTPM]":"17.1","Tissue RNA - skin 1 [nTPM]":"26.2","Tissue RNA - small intestine [nTPM]":"27.9","Tissue RNA - smooth muscle [nTPM]":"40.0","Tissue RNA - spinal cord [nTPM]":"54.5","Tissue RNA - spleen [nTPM]":"37.0","Tissue RNA - stomach 1 [nTPM]":"39.2","Tissue RNA - testis [nTPM]":"13.7","Tissue RNA - thalamus [nTPM]":"65.8","Tissue RNA - thymus [nTPM]":"24.0","Tissue RNA - thyroid gland [nTPM]":"37.8","Tissue RNA - tongue [nTPM]":"17.2","Tissue RNA - tonsil [nTPM]":"42.5","Tissue RNA - urinary bladder [nTPM]":"78.8","Tissue RNA - vagina [nTPM]":"42.7","Tissue RNA - white matter [nTPM]":"117.4","Cell RNA - A-431 [nTPM]":"74.6","Cell RNA - A549 [nTPM]":"30.4","Cell RNA - AF22 [nTPM]":"47.1","Cell RNA - AN3-CA [nTPM]":"50.2","Cell RNA - ASC diff [nTPM]":"143.5","Cell RNA - ASC TERT1 [nTPM]":"105.4","Cell RNA - BEWO [nTPM]":"50.0","Cell RNA - BJ [nTPM]":"138.6","Cell RNA - BJ hTERT+ [nTPM]":"212.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"98.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"106.7","Cell RNA - CACO-2 [nTPM]":"34.2","Cell RNA - CAPAN-2 [nTPM]":"108.3","Cell RNA - Daudi [nTPM]":"76.9","Cell RNA - EFO-21 [nTPM]":"98.3","Cell RNA - fHDF\/TERT166 [nTPM]":"85.9","Cell RNA - GAMG [nTPM]":"56.2","Cell RNA - HaCaT [nTPM]":"53.8","Cell RNA - HAP1 [nTPM]":"50.0","Cell RNA - HBEC3-KT [nTPM]":"56.8","Cell RNA - HBF TERT88 [nTPM]":"98.9","Cell RNA - HDLM-2 [nTPM]":"43.8","Cell RNA - HEK 293 [nTPM]":"46.4","Cell RNA - HEL [nTPM]":"66.0","Cell RNA - HeLa [nTPM]":"50.1","Cell RNA - Hep G2 [nTPM]":"66.6","Cell RNA - HHSteC [nTPM]":"89.1","Cell RNA - HL-60 [nTPM]":"92.1","Cell RNA - HMC-1 [nTPM]":"75.1","Cell RNA - HSkMC [nTPM]":"109.1","Cell RNA - hTCEpi [nTPM]":"72.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"55.9","Cell RNA - hTERT-HME1 [nTPM]":"37.3","Cell RNA - hTERT-RPE1 [nTPM]":"82.4","Cell RNA - HUVEC TERT2 [nTPM]":"113.2","Cell RNA - JURKAT [nTPM]":"25.6","Cell RNA - K-562 [nTPM]":"112.8","Cell RNA - Karpas-707 [nTPM]":"47.8","Cell RNA - LHCN-M2 [nTPM]":"116.5","Cell RNA - MCF7 [nTPM]":"54.5","Cell RNA - MOLT-4 [nTPM]":"73.0","Cell RNA - NB-4 [nTPM]":"76.5","Cell RNA - NTERA-2 [nTPM]":"51.7","Cell RNA - OE19 [nTPM]":"97.8","Cell RNA - PC-3 [nTPM]":"70.6","Cell RNA - REH [nTPM]":"52.0","Cell RNA - RH-30 [nTPM]":"35.5","Cell RNA - RPMI-8226 [nTPM]":"42.1","Cell RNA - RPTEC TERT1 [nTPM]":"148.6","Cell RNA - RT4 [nTPM]":"70.2","Cell RNA - SCLC-21H [nTPM]":"48.3","Cell RNA - SH-SY5Y [nTPM]":"64.7","Cell RNA - SiHa [nTPM]":"69.8","Cell RNA - SK-BR-3 [nTPM]":"261.0","Cell RNA - SK-MEL-30 [nTPM]":"85.8","Cell RNA - SuSa [nTPM]":"46.3","Cell RNA - T-47d [nTPM]":"41.2","Cell RNA - THP-1 [nTPM]":"65.3","Cell RNA - TIME [nTPM]":"98.3","Cell RNA - U-138 MG [nTPM]":"83.1","Cell RNA - U-2 OS [nTPM]":"49.6","Cell RNA - U-2197 [nTPM]":"37.0","Cell RNA - U-251 MG [nTPM]":"102.5","Cell RNA - U-266\/70 [nTPM]":"44.4","Cell RNA - U-266\/84 [nTPM]":"38.5","Cell RNA - U-698 [nTPM]":"48.3","Cell RNA - U-87 MG [nTPM]":"98.9","Cell RNA - U-937 [nTPM]":"77.2","Cell RNA - WM-115 [nTPM]":"67.9","Blood RNA - basophil [nTPM]":"23.7","Blood RNA - classical monocyte [nTPM]":"40.4","Blood RNA - eosinophil [nTPM]":"26.0","Blood RNA - gdT-cell [nTPM]":"15.2","Blood RNA - intermediate monocyte [nTPM]":"35.7","Blood RNA - MAIT T-cell [nTPM]":"17.0","Blood RNA - memory B-cell [nTPM]":"19.0","Blood RNA - memory CD4 T-cell [nTPM]":"14.3","Blood RNA - memory CD8 T-cell [nTPM]":"17.8","Blood RNA - myeloid DC [nTPM]":"36.5","Blood RNA - naive B-cell [nTPM]":"11.5","Blood RNA - naive CD4 T-cell [nTPM]":"12.1","Blood RNA - naive CD8 T-cell [nTPM]":"14.4","Blood RNA - neutrophil [nTPM]":"28.6","Blood RNA - NK-cell [nTPM]":"18.1","Blood RNA - non-classical monocyte [nTPM]":"35.9","Blood RNA - plasmacytoid DC [nTPM]":"28.4","Blood RNA - T-reg [nTPM]":"18.3","Blood RNA - total PBMC [nTPM]":"30.2","Brain RNA - amygdala [nTPM]":"39.2","Brain RNA - basal ganglia [nTPM]":"75.1","Brain RNA - cerebellum [nTPM]":"62.0","Brain RNA - cerebral cortex [nTPM]":"70.8","Brain RNA - hippocampal formation [nTPM]":"40.8","Brain RNA - hypothalamus [nTPM]":"51.1","Brain RNA - medulla oblongata [nTPM]":"84.8","Brain RNA - midbrain [nTPM]":"72.0","Brain RNA - pons [nTPM]":"78.9","Brain RNA - spinal cord [nTPM]":"54.5","Brain RNA - thalamus [nTPM]":"65.8","Brain RNA - white matter [nTPM]":"117.4","Single Cell Type RNA - Adipocytes [nTPM]":"119.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"54.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"52.4","Single Cell Type RNA - Astrocytes [nTPM]":"42.7","Single Cell Type RNA - B-cells [nTPM]":"87.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"245.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"277.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"295.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"147.4","Single Cell Type RNA - Bipolar cells [nTPM]":"50.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"85.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"42.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"32.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"71.4","Single Cell Type RNA - Club cells [nTPM]":"214.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"79.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"81.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"112.5","Single Cell Type RNA - dendritic cells [nTPM]":"97.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"42.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"171.1","Single Cell Type RNA - Early spermatids [nTPM]":"32.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"123.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"99.1","Single Cell Type RNA - Endothelial cells [nTPM]":"108.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"50.4","Single Cell Type RNA - Erythroid cells [nTPM]":"79.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"58.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"163.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"157.2","Single Cell Type RNA - Fibroblasts [nTPM]":"110.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"76.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"173.8","Single Cell Type RNA - granulocytes [nTPM]":"21.0","Single Cell Type RNA - Granulosa cells [nTPM]":"57.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"113.8","Single Cell Type RNA - Hepatocytes [nTPM]":"18.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"105.7","Single Cell Type RNA - Horizontal cells [nTPM]":"28.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"71.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"69.4","Single Cell Type RNA - Ionocytes [nTPM]":"77.3","Single Cell Type RNA - Kupffer cells [nTPM]":"97.9","Single Cell Type RNA - Langerhans cells [nTPM]":"145.7","Single Cell Type RNA - Late spermatids [nTPM]":"24.7","Single Cell Type RNA - Leydig cells [nTPM]":"58.7","Single Cell Type RNA - Macrophages [nTPM]":"109.5","Single Cell Type RNA - Melanocytes [nTPM]":"88.9","Single Cell Type RNA - Microglial cells [nTPM]":"59.0","Single Cell Type RNA - monocytes [nTPM]":"117.5","Single Cell Type RNA - Muller glia cells [nTPM]":"53.2","Single Cell Type RNA - NK-cells [nTPM]":"123.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"71.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1021.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"248.0","Single Cell Type RNA - Paneth cells [nTPM]":"48.6","Single Cell Type RNA - Peritubular cells [nTPM]":"63.6","Single Cell Type RNA - Plasma cells [nTPM]":"117.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"239.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"51.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"50.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"125.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"91.9","Single Cell Type RNA - Sertoli cells [nTPM]":"98.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"92.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"129.0","Single Cell Type RNA - Spermatocytes [nTPM]":"37.8","Single Cell Type RNA - Spermatogonia [nTPM]":"24.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"169.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"268.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"80.6","Single Cell Type RNA - T-cells [nTPM]":"81.6","Single Cell Type RNA - Theca cells [nTPM]":"90.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"61.6","Single Cell Type RNA - Urothelial cells [nTPM]":"601.6"},{"Gene":"TMEM175","Gene synonym":["MGC4618"],"Ensembl":"ENSG00000127419","Gene description":"Transmembrane protein 175","Uniprot":["Q9BSA9"],"Chromosome":"4","Position":"932387-958656","Protein class":["Disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel"],"Disease involvement":["Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057160"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 62: Horizontal cells - Visual perception","Subcellular main location":["Nucleoplasm","Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA057160":"AB_2683356"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.61e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.85e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-3"},"Tissue RNA - adipose tissue [nTPM]":"17.5","Tissue RNA - adrenal gland [nTPM]":"28.2","Tissue RNA - amygdala [nTPM]":"13.0","Tissue RNA - appendix [nTPM]":"8.1","Tissue RNA - basal ganglia [nTPM]":"13.3","Tissue RNA - bone marrow [nTPM]":"12.9","Tissue RNA - breast [nTPM]":"17.5","Tissue RNA - cerebellum [nTPM]":"15.7","Tissue RNA - cerebral cortex [nTPM]":"24.6","Tissue RNA - cervix [nTPM]":"14.7","Tissue RNA - choroid plexus [nTPM]":"12.2","Tissue RNA - colon [nTPM]":"15.5","Tissue RNA - duodenum [nTPM]":"8.9","Tissue RNA - endometrium 1 [nTPM]":"17.3","Tissue RNA - epididymis [nTPM]":"6.0","Tissue RNA - esophagus [nTPM]":"14.2","Tissue RNA - fallopian tube [nTPM]":"14.9","Tissue RNA - gallbladder [nTPM]":"10.0","Tissue RNA - heart muscle [nTPM]":"19.6","Tissue RNA - hippocampal formation [nTPM]":"12.9","Tissue RNA - hypothalamus [nTPM]":"13.1","Tissue RNA - kidney [nTPM]":"16.4","Tissue RNA - liver [nTPM]":"33.5","Tissue RNA - lung [nTPM]":"16.1","Tissue RNA - lymph node [nTPM]":"16.1","Tissue RNA - medulla oblongata [nTPM]":"14.6","Tissue RNA - midbrain [nTPM]":"13.1","Tissue RNA - ovary [nTPM]":"12.2","Tissue RNA - pancreas [nTPM]":"23.3","Tissue RNA - parathyroid gland [nTPM]":"9.2","Tissue RNA - pituitary gland [nTPM]":"30.9","Tissue RNA - placenta [nTPM]":"7.4","Tissue RNA - pons [nTPM]":"14.5","Tissue RNA - prostate [nTPM]":"19.0","Tissue RNA - rectum [nTPM]":"3.6","Tissue RNA - retina [nTPM]":"10.2","Tissue RNA - salivary gland [nTPM]":"21.4","Tissue RNA - seminal vesicle [nTPM]":"8.7","Tissue RNA - skeletal muscle [nTPM]":"19.7","Tissue RNA - skin 1 [nTPM]":"17.0","Tissue RNA - small intestine [nTPM]":"17.5","Tissue RNA - smooth muscle [nTPM]":"6.4","Tissue RNA - spinal cord [nTPM]":"11.4","Tissue RNA - spleen [nTPM]":"26.1","Tissue RNA - stomach 1 [nTPM]":"19.3","Tissue RNA - testis [nTPM]":"13.2","Tissue RNA - thalamus [nTPM]":"12.7","Tissue RNA - thymus [nTPM]":"8.9","Tissue RNA - thyroid gland [nTPM]":"21.0","Tissue RNA - tongue [nTPM]":"4.5","Tissue RNA - tonsil [nTPM]":"6.1","Tissue RNA - urinary bladder [nTPM]":"16.1","Tissue RNA - vagina [nTPM]":"13.5","Tissue RNA - white matter [nTPM]":"13.5","Cell RNA - A-431 [nTPM]":"4.9","Cell RNA - A549 [nTPM]":"9.5","Cell RNA - AF22 [nTPM]":"5.1","Cell RNA - AN3-CA [nTPM]":"7.0","Cell RNA - ASC diff [nTPM]":"23.7","Cell RNA - ASC TERT1 [nTPM]":"12.3","Cell RNA - BEWO [nTPM]":"11.8","Cell RNA - BJ [nTPM]":"13.0","Cell RNA - BJ hTERT+ [nTPM]":"8.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.8","Cell RNA - CACO-2 [nTPM]":"4.2","Cell RNA - CAPAN-2 [nTPM]":"20.5","Cell RNA - Daudi [nTPM]":"4.0","Cell RNA - EFO-21 [nTPM]":"7.5","Cell RNA - fHDF\/TERT166 [nTPM]":"12.8","Cell RNA - GAMG [nTPM]":"12.8","Cell RNA - HaCaT [nTPM]":"8.4","Cell RNA - HAP1 [nTPM]":"4.7","Cell RNA - HBEC3-KT [nTPM]":"9.5","Cell RNA - HBF TERT88 [nTPM]":"3.1","Cell RNA - HDLM-2 [nTPM]":"9.2","Cell RNA - HEK 293 [nTPM]":"11.9","Cell RNA - HEL [nTPM]":"8.3","Cell RNA - HeLa [nTPM]":"14.9","Cell RNA - Hep G2 [nTPM]":"4.3","Cell RNA - HHSteC [nTPM]":"13.7","Cell RNA - HL-60 [nTPM]":"4.6","Cell RNA - HMC-1 [nTPM]":"14.8","Cell RNA - HSkMC [nTPM]":"17.5","Cell RNA - hTCEpi [nTPM]":"11.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.4","Cell RNA - hTERT-HME1 [nTPM]":"4.3","Cell RNA - hTERT-RPE1 [nTPM]":"5.1","Cell RNA - HUVEC TERT2 [nTPM]":"4.6","Cell RNA - JURKAT [nTPM]":"8.1","Cell RNA - K-562 [nTPM]":"8.2","Cell RNA - Karpas-707 [nTPM]":"30.0","Cell RNA - LHCN-M2 [nTPM]":"6.4","Cell RNA - MCF7 [nTPM]":"16.2","Cell RNA - MOLT-4 [nTPM]":"11.3","Cell RNA - NB-4 [nTPM]":"17.4","Cell RNA - NTERA-2 [nTPM]":"3.2","Cell RNA - OE19 [nTPM]":"5.8","Cell RNA - PC-3 [nTPM]":"24.8","Cell RNA - REH [nTPM]":"7.5","Cell RNA - RH-30 [nTPM]":"3.1","Cell RNA - RPMI-8226 [nTPM]":"11.5","Cell RNA - RPTEC TERT1 [nTPM]":"7.0","Cell RNA - RT4 [nTPM]":"5.0","Cell RNA - SCLC-21H [nTPM]":"14.0","Cell RNA - SH-SY5Y [nTPM]":"12.9","Cell RNA - SiHa [nTPM]":"8.6","Cell RNA - SK-BR-3 [nTPM]":"5.5","Cell RNA - SK-MEL-30 [nTPM]":"7.8","Cell RNA - SuSa [nTPM]":"2.5","Cell RNA - T-47d [nTPM]":"24.3","Cell RNA - THP-1 [nTPM]":"11.3","Cell RNA - TIME [nTPM]":"6.6","Cell RNA - U-138 MG [nTPM]":"13.7","Cell RNA - U-2 OS [nTPM]":"3.0","Cell RNA - U-2197 [nTPM]":"16.8","Cell RNA - U-251 MG [nTPM]":"9.1","Cell RNA - U-266\/70 [nTPM]":"23.0","Cell RNA - U-266\/84 [nTPM]":"5.9","Cell RNA - U-698 [nTPM]":"7.4","Cell RNA - U-87 MG [nTPM]":"13.2","Cell RNA - U-937 [nTPM]":"9.4","Cell RNA - WM-115 [nTPM]":"11.3","Blood RNA - basophil [nTPM]":"36.8","Blood RNA - classical monocyte [nTPM]":"32.2","Blood RNA - eosinophil [nTPM]":"27.2","Blood RNA - gdT-cell [nTPM]":"20.6","Blood RNA - intermediate monocyte [nTPM]":"41.1","Blood RNA - MAIT T-cell [nTPM]":"13.3","Blood RNA - memory B-cell [nTPM]":"19.4","Blood RNA - memory CD4 T-cell [nTPM]":"17.3","Blood RNA - memory CD8 T-cell [nTPM]":"15.5","Blood RNA - myeloid DC [nTPM]":"29.4","Blood RNA - naive B-cell [nTPM]":"21.6","Blood RNA - naive CD4 T-cell [nTPM]":"12.6","Blood RNA - naive CD8 T-cell [nTPM]":"17.6","Blood RNA - neutrophil [nTPM]":"27.8","Blood RNA - NK-cell [nTPM]":"17.0","Blood RNA - non-classical monocyte [nTPM]":"39.7","Blood RNA - plasmacytoid DC [nTPM]":"47.1","Blood RNA - T-reg [nTPM]":"18.5","Blood RNA - total PBMC [nTPM]":"21.2","Brain RNA - amygdala [nTPM]":"13.0","Brain RNA - basal ganglia [nTPM]":"13.3","Brain RNA - cerebellum [nTPM]":"15.7","Brain RNA - cerebral cortex [nTPM]":"24.6","Brain RNA - hippocampal formation [nTPM]":"12.9","Brain RNA - hypothalamus [nTPM]":"13.1","Brain RNA - medulla oblongata [nTPM]":"14.6","Brain RNA - midbrain [nTPM]":"13.1","Brain RNA - pons [nTPM]":"14.5","Brain RNA - spinal cord [nTPM]":"11.4","Brain RNA - thalamus [nTPM]":"12.7","Brain RNA - white matter [nTPM]":"13.5","Single Cell Type RNA - Adipocytes [nTPM]":"17.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.9","Single Cell Type RNA - Astrocytes [nTPM]":"26.8","Single Cell Type RNA - B-cells [nTPM]":"20.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Bipolar cells [nTPM]":"26.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"17.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"24.1","Single Cell Type RNA - dendritic cells [nTPM]":"19.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.8","Single Cell Type RNA - Early spermatids [nTPM]":"6.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.2","Single Cell Type RNA - Endothelial cells [nTPM]":"10.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.2","Single Cell Type RNA - Erythroid cells [nTPM]":"3.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"42.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.1","Single Cell Type RNA - Fibroblasts [nTPM]":"16.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.3","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"10.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.8","Single Cell Type RNA - Hepatocytes [nTPM]":"24.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.2","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.6","Single Cell Type RNA - Ionocytes [nTPM]":"34.6","Single Cell Type RNA - Kupffer cells [nTPM]":"14.5","Single Cell Type RNA - Langerhans cells [nTPM]":"9.1","Single Cell Type RNA - Late spermatids [nTPM]":"4.0","Single Cell Type RNA - Leydig cells [nTPM]":"12.5","Single Cell Type RNA - Macrophages [nTPM]":"15.8","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"9.6","Single Cell Type RNA - Muller glia cells [nTPM]":"38.6","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"25.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"29.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.9","Single Cell Type RNA - Paneth cells [nTPM]":"16.1","Single Cell Type RNA - Peritubular cells [nTPM]":"16.1","Single Cell Type RNA - Plasma cells [nTPM]":"16.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"16.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"28.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.3","Single Cell Type RNA - Spermatocytes [nTPM]":"24.0","Single Cell Type RNA - Spermatogonia [nTPM]":"14.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"18.9","Single Cell Type RNA - T-cells [nTPM]":"15.3","Single Cell Type RNA - Theca cells [nTPM]":"29.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.6","Single Cell Type RNA - Urothelial cells [nTPM]":"8.4"},{"Gene":"TMEM199","Gene synonym":["C17orf32","MGC45714","VMA12","VPH2"],"Ensembl":"ENSG00000244045","Gene description":"Transmembrane protein 199","Uniprot":["Q8N511"],"Chromosome":"17","Position":"28357642-28363683","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027051"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 3: Monocytes - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA027051":"AB_10600915"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.55e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.54e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.3","Tissue RNA - adrenal gland [nTPM]":"11.9","Tissue RNA - amygdala [nTPM]":"9.2","Tissue RNA - appendix [nTPM]":"10.3","Tissue RNA - basal ganglia [nTPM]":"10.4","Tissue RNA - bone marrow [nTPM]":"13.3","Tissue RNA - breast [nTPM]":"8.6","Tissue RNA - cerebellum [nTPM]":"10.1","Tissue RNA - cerebral cortex [nTPM]":"13.0","Tissue RNA - cervix [nTPM]":"9.1","Tissue RNA - choroid plexus [nTPM]":"9.6","Tissue RNA - colon [nTPM]":"9.0","Tissue RNA - duodenum [nTPM]":"7.4","Tissue RNA - endometrium 1 [nTPM]":"9.5","Tissue RNA - epididymis [nTPM]":"9.6","Tissue RNA - esophagus [nTPM]":"10.6","Tissue RNA - fallopian tube [nTPM]":"8.0","Tissue RNA - gallbladder [nTPM]":"6.2","Tissue RNA - heart muscle [nTPM]":"9.3","Tissue RNA - hippocampal formation [nTPM]":"9.5","Tissue RNA - hypothalamus [nTPM]":"10.5","Tissue RNA - kidney [nTPM]":"12.9","Tissue RNA - liver [nTPM]":"14.4","Tissue RNA - lung [nTPM]":"8.5","Tissue RNA - lymph node [nTPM]":"12.7","Tissue RNA - medulla oblongata [nTPM]":"10.2","Tissue RNA - midbrain [nTPM]":"10.1","Tissue RNA - ovary [nTPM]":"8.0","Tissue RNA - pancreas [nTPM]":"8.9","Tissue RNA - parathyroid gland [nTPM]":"15.5","Tissue RNA - pituitary gland [nTPM]":"11.7","Tissue RNA - placenta [nTPM]":"9.5","Tissue RNA - pons [nTPM]":"10.1","Tissue RNA - prostate [nTPM]":"9.8","Tissue RNA - rectum [nTPM]":"7.9","Tissue RNA - retina [nTPM]":"13.9","Tissue RNA - salivary gland [nTPM]":"9.5","Tissue RNA - seminal vesicle [nTPM]":"6.8","Tissue RNA - skeletal muscle [nTPM]":"7.2","Tissue RNA - skin 1 [nTPM]":"11.6","Tissue RNA - small intestine [nTPM]":"9.0","Tissue RNA - smooth muscle [nTPM]":"6.2","Tissue RNA - spinal cord [nTPM]":"9.5","Tissue RNA - spleen [nTPM]":"13.2","Tissue RNA - stomach 1 [nTPM]":"8.9","Tissue RNA - testis [nTPM]":"7.8","Tissue RNA - thalamus [nTPM]":"10.4","Tissue RNA - thymus [nTPM]":"12.8","Tissue RNA - thyroid gland [nTPM]":"10.8","Tissue RNA - tongue [nTPM]":"7.5","Tissue RNA - tonsil [nTPM]":"11.2","Tissue RNA - urinary bladder [nTPM]":"8.8","Tissue RNA - vagina [nTPM]":"8.8","Tissue RNA - white matter [nTPM]":"12.0","Cell RNA - A-431 [nTPM]":"12.2","Cell RNA - A549 [nTPM]":"20.4","Cell RNA - AF22 [nTPM]":"19.6","Cell RNA - AN3-CA [nTPM]":"16.7","Cell RNA - ASC diff [nTPM]":"7.9","Cell RNA - ASC TERT1 [nTPM]":"6.8","Cell RNA - BEWO [nTPM]":"16.5","Cell RNA - BJ [nTPM]":"14.8","Cell RNA - BJ hTERT+ [nTPM]":"9.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"18.5","Cell RNA - CACO-2 [nTPM]":"48.9","Cell RNA - CAPAN-2 [nTPM]":"9.6","Cell RNA - Daudi [nTPM]":"17.6","Cell RNA - EFO-21 [nTPM]":"14.8","Cell RNA - fHDF\/TERT166 [nTPM]":"11.0","Cell RNA - GAMG [nTPM]":"26.4","Cell RNA - HaCaT [nTPM]":"20.6","Cell RNA - HAP1 [nTPM]":"21.8","Cell RNA - HBEC3-KT [nTPM]":"13.9","Cell RNA - HBF TERT88 [nTPM]":"18.0","Cell RNA - HDLM-2 [nTPM]":"32.8","Cell RNA - HEK 293 [nTPM]":"19.6","Cell RNA - HEL [nTPM]":"13.0","Cell RNA - HeLa [nTPM]":"17.7","Cell RNA - Hep G2 [nTPM]":"23.6","Cell RNA - HHSteC [nTPM]":"15.9","Cell RNA - HL-60 [nTPM]":"18.7","Cell RNA - HMC-1 [nTPM]":"22.0","Cell RNA - HSkMC [nTPM]":"9.7","Cell RNA - hTCEpi [nTPM]":"12.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.6","Cell RNA - hTERT-HME1 [nTPM]":"13.0","Cell RNA - hTERT-RPE1 [nTPM]":"12.2","Cell RNA - HUVEC TERT2 [nTPM]":"10.2","Cell RNA - JURKAT [nTPM]":"16.1","Cell RNA - K-562 [nTPM]":"21.6","Cell RNA - Karpas-707 [nTPM]":"21.8","Cell RNA - LHCN-M2 [nTPM]":"15.4","Cell RNA - MCF7 [nTPM]":"24.1","Cell RNA - MOLT-4 [nTPM]":"21.3","Cell RNA - NB-4 [nTPM]":"25.6","Cell RNA - NTERA-2 [nTPM]":"16.2","Cell RNA - OE19 [nTPM]":"21.0","Cell RNA - PC-3 [nTPM]":"13.9","Cell RNA - REH [nTPM]":"17.2","Cell RNA - RH-30 [nTPM]":"24.4","Cell RNA - RPMI-8226 [nTPM]":"16.3","Cell RNA - RPTEC TERT1 [nTPM]":"15.5","Cell RNA - RT4 [nTPM]":"20.2","Cell RNA - SCLC-21H [nTPM]":"24.8","Cell RNA - SH-SY5Y [nTPM]":"26.0","Cell RNA - SiHa [nTPM]":"17.8","Cell RNA - SK-BR-3 [nTPM]":"45.6","Cell RNA - SK-MEL-30 [nTPM]":"27.1","Cell RNA - SuSa [nTPM]":"20.1","Cell RNA - T-47d [nTPM]":"28.7","Cell RNA - THP-1 [nTPM]":"16.9","Cell RNA - TIME [nTPM]":"14.0","Cell RNA - U-138 MG [nTPM]":"17.4","Cell RNA - U-2 OS [nTPM]":"13.5","Cell RNA - U-2197 [nTPM]":"15.0","Cell RNA - U-251 MG [nTPM]":"25.3","Cell RNA - U-266\/70 [nTPM]":"29.3","Cell RNA - U-266\/84 [nTPM]":"38.9","Cell RNA - U-698 [nTPM]":"16.2","Cell RNA - U-87 MG [nTPM]":"21.6","Cell RNA - U-937 [nTPM]":"11.4","Cell RNA - WM-115 [nTPM]":"22.2","Blood RNA - basophil [nTPM]":"28.5","Blood RNA - classical monocyte [nTPM]":"24.2","Blood RNA - eosinophil [nTPM]":"20.0","Blood RNA - gdT-cell [nTPM]":"15.1","Blood RNA - intermediate monocyte [nTPM]":"25.2","Blood RNA - MAIT T-cell [nTPM]":"16.6","Blood RNA - memory B-cell [nTPM]":"17.1","Blood RNA - memory CD4 T-cell [nTPM]":"13.1","Blood RNA - memory CD8 T-cell [nTPM]":"13.4","Blood RNA - myeloid DC [nTPM]":"20.0","Blood RNA - naive B-cell [nTPM]":"16.0","Blood RNA - naive CD4 T-cell [nTPM]":"16.4","Blood RNA - naive CD8 T-cell [nTPM]":"14.5","Blood RNA - neutrophil [nTPM]":"18.9","Blood RNA - NK-cell [nTPM]":"15.6","Blood RNA - non-classical monocyte [nTPM]":"23.0","Blood RNA - plasmacytoid DC [nTPM]":"14.0","Blood RNA - T-reg [nTPM]":"14.9","Blood RNA - total PBMC [nTPM]":"19.1","Brain RNA - amygdala [nTPM]":"9.2","Brain RNA - basal ganglia [nTPM]":"10.4","Brain RNA - cerebellum [nTPM]":"10.1","Brain RNA - cerebral cortex [nTPM]":"13.0","Brain RNA - hippocampal formation [nTPM]":"9.5","Brain RNA - hypothalamus [nTPM]":"10.5","Brain RNA - medulla oblongata [nTPM]":"10.2","Brain RNA - midbrain [nTPM]":"10.1","Brain RNA - pons [nTPM]":"10.1","Brain RNA - spinal cord [nTPM]":"9.5","Brain RNA - thalamus [nTPM]":"10.4","Brain RNA - white matter [nTPM]":"12.0","Single Cell Type RNA - Adipocytes [nTPM]":"12.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.6","Single Cell Type RNA - Astrocytes [nTPM]":"8.8","Single Cell Type RNA - B-cells [nTPM]":"21.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"34.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Bipolar cells [nTPM]":"13.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"23.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"40.2","Single Cell Type RNA - dendritic cells [nTPM]":"15.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"21.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"43.0","Single Cell Type RNA - Ductal cells [nTPM]":"40.2","Single Cell Type RNA - Early spermatids [nTPM]":"3.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.4","Single Cell Type RNA - Endothelial cells [nTPM]":"14.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.6","Single Cell Type RNA - Erythroid cells [nTPM]":"12.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"31.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"38.1","Single Cell Type RNA - Fibroblasts [nTPM]":"10.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.9","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"11.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.5","Single Cell Type RNA - Hepatocytes [nTPM]":"26.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"51.3","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.7","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"22.9","Single Cell Type RNA - Langerhans cells [nTPM]":"9.5","Single Cell Type RNA - Late spermatids [nTPM]":"4.5","Single Cell Type RNA - Leydig cells [nTPM]":"11.5","Single Cell Type RNA - Macrophages [nTPM]":"22.4","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"45.0","Single Cell Type RNA - Muller glia cells [nTPM]":"19.1","Single Cell Type RNA - NK-cells [nTPM]":"25.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"13.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"35.4","Single Cell Type RNA - Paneth cells [nTPM]":"19.4","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"15.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"54.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.2","Single Cell Type RNA - Spermatocytes [nTPM]":"26.5","Single Cell Type RNA - Spermatogonia [nTPM]":"35.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"48.4","Single Cell Type RNA - T-cells [nTPM]":"15.2","Single Cell Type RNA - Theca cells [nTPM]":"14.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.0","Single Cell Type RNA - Urothelial cells [nTPM]":"11.4"},{"Gene":"TMEM237","Gene synonym":["ALS2CR4","JBTS14"],"Ensembl":"ENSG00000155755","Gene description":"Transmembrane protein 237","Uniprot":["Q96Q45"],"Chromosome":"2","Position":"201620184-201643570","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":null,"Disease involvement":["Ciliopathy","Joubert syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"retina":"89.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"81.7","Rod photoreceptor cells":"160.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052596","HPA054732"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052596":"AB_2681879","HPA054732":"AB_2682587"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.51e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.33e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.96e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Tissue RNA - adipose tissue [nTPM]":"4.1","Tissue RNA - adrenal gland [nTPM]":"15.1","Tissue RNA - amygdala [nTPM]":"6.3","Tissue RNA - appendix [nTPM]":"1.7","Tissue RNA - basal ganglia [nTPM]":"6.5","Tissue RNA - bone marrow [nTPM]":"2.3","Tissue RNA - breast [nTPM]":"11.0","Tissue RNA - cerebellum [nTPM]":"7.1","Tissue RNA - cerebral cortex [nTPM]":"7.8","Tissue RNA - cervix [nTPM]":"5.0","Tissue RNA - choroid plexus [nTPM]":"6.0","Tissue RNA - colon [nTPM]":"3.0","Tissue RNA - duodenum [nTPM]":"0.8","Tissue RNA - endometrium 1 [nTPM]":"6.0","Tissue RNA - epididymis [nTPM]":"4.6","Tissue RNA - esophagus [nTPM]":"6.0","Tissue RNA - fallopian tube [nTPM]":"5.8","Tissue RNA - gallbladder [nTPM]":"4.1","Tissue RNA - heart muscle [nTPM]":"7.7","Tissue RNA - hippocampal formation [nTPM]":"6.8","Tissue RNA - hypothalamus [nTPM]":"6.7","Tissue RNA - kidney [nTPM]":"5.4","Tissue RNA - liver [nTPM]":"1.9","Tissue RNA - lung [nTPM]":"5.1","Tissue RNA - lymph node [nTPM]":"2.3","Tissue RNA - medulla oblongata [nTPM]":"6.9","Tissue RNA - midbrain [nTPM]":"6.9","Tissue RNA - ovary [nTPM]":"8.4","Tissue RNA - pancreas [nTPM]":"1.9","Tissue RNA - parathyroid gland [nTPM]":"5.0","Tissue RNA - pituitary gland [nTPM]":"3.0","Tissue RNA - placenta [nTPM]":"5.2","Tissue RNA - pons [nTPM]":"7.2","Tissue RNA - prostate [nTPM]":"7.8","Tissue RNA - rectum [nTPM]":"3.7","Tissue RNA - retina [nTPM]":"89.3","Tissue RNA - salivary gland [nTPM]":"5.1","Tissue RNA - seminal vesicle [nTPM]":"4.8","Tissue RNA - skeletal muscle [nTPM]":"7.7","Tissue RNA - skin 1 [nTPM]":"18.5","Tissue RNA - small intestine [nTPM]":"1.8","Tissue RNA - smooth muscle [nTPM]":"5.8","Tissue RNA - spinal cord [nTPM]":"7.1","Tissue RNA - spleen [nTPM]":"1.4","Tissue RNA - stomach 1 [nTPM]":"2.2","Tissue RNA - testis [nTPM]":"3.0","Tissue RNA - thalamus [nTPM]":"6.4","Tissue RNA - thymus [nTPM]":"7.0","Tissue RNA - thyroid gland [nTPM]":"4.6","Tissue RNA - tongue [nTPM]":"9.2","Tissue RNA - tonsil [nTPM]":"3.1","Tissue RNA - urinary bladder [nTPM]":"4.1","Tissue RNA - vagina [nTPM]":"3.4","Tissue RNA - white matter [nTPM]":"6.8","Cell RNA - A-431 [nTPM]":"3.7","Cell RNA - A549 [nTPM]":"7.2","Cell RNA - AF22 [nTPM]":"32.3","Cell RNA - AN3-CA [nTPM]":"16.4","Cell RNA - ASC diff [nTPM]":"7.8","Cell RNA - ASC TERT1 [nTPM]":"10.1","Cell RNA - BEWO [nTPM]":"3.1","Cell RNA - BJ [nTPM]":"22.6","Cell RNA - BJ hTERT+ [nTPM]":"9.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"28.4","Cell RNA - CACO-2 [nTPM]":"5.9","Cell RNA - CAPAN-2 [nTPM]":"5.3","Cell RNA - Daudi [nTPM]":"3.7","Cell RNA - EFO-21 [nTPM]":"6.9","Cell RNA - fHDF\/TERT166 [nTPM]":"21.9","Cell RNA - GAMG [nTPM]":"12.7","Cell RNA - HaCaT [nTPM]":"6.8","Cell RNA - HAP1 [nTPM]":"5.6","Cell RNA - HBEC3-KT [nTPM]":"24.4","Cell RNA - HBF TERT88 [nTPM]":"27.1","Cell RNA - HDLM-2 [nTPM]":"6.9","Cell RNA - HEK 293 [nTPM]":"20.6","Cell RNA - HEL [nTPM]":"10.7","Cell RNA - HeLa [nTPM]":"21.4","Cell RNA - Hep G2 [nTPM]":"19.4","Cell RNA - HHSteC [nTPM]":"15.1","Cell RNA - HL-60 [nTPM]":"10.4","Cell RNA - HMC-1 [nTPM]":"2.1","Cell RNA - HSkMC [nTPM]":"9.0","Cell RNA - hTCEpi [nTPM]":"5.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.4","Cell RNA - hTERT-HME1 [nTPM]":"5.1","Cell RNA - hTERT-RPE1 [nTPM]":"24.8","Cell RNA - HUVEC TERT2 [nTPM]":"25.5","Cell RNA - JURKAT [nTPM]":"23.4","Cell RNA - K-562 [nTPM]":"7.8","Cell RNA - Karpas-707 [nTPM]":"13.0","Cell RNA - LHCN-M2 [nTPM]":"29.8","Cell RNA - MCF7 [nTPM]":"5.2","Cell RNA - MOLT-4 [nTPM]":"29.7","Cell RNA - NB-4 [nTPM]":"16.3","Cell RNA - NTERA-2 [nTPM]":"32.7","Cell RNA - OE19 [nTPM]":"1.9","Cell RNA - PC-3 [nTPM]":"23.8","Cell RNA - REH [nTPM]":"43.9","Cell RNA - RH-30 [nTPM]":"30.8","Cell RNA - RPMI-8226 [nTPM]":"7.6","Cell RNA - RPTEC TERT1 [nTPM]":"12.2","Cell RNA - RT4 [nTPM]":"9.7","Cell RNA - SCLC-21H [nTPM]":"33.7","Cell RNA - SH-SY5Y [nTPM]":"47.4","Cell RNA - SiHa [nTPM]":"21.4","Cell RNA - SK-BR-3 [nTPM]":"8.4","Cell RNA - SK-MEL-30 [nTPM]":"12.6","Cell RNA - SuSa [nTPM]":"20.3","Cell RNA - T-47d [nTPM]":"12.5","Cell RNA - THP-1 [nTPM]":"18.7","Cell RNA - TIME [nTPM]":"6.8","Cell RNA - U-138 MG [nTPM]":"26.8","Cell RNA - U-2 OS [nTPM]":"7.3","Cell RNA - U-2197 [nTPM]":"8.6","Cell RNA - U-251 MG [nTPM]":"9.5","Cell RNA - U-266\/70 [nTPM]":"6.0","Cell RNA - U-266\/84 [nTPM]":"14.9","Cell RNA - U-698 [nTPM]":"11.4","Cell RNA - U-87 MG [nTPM]":"22.7","Cell RNA - U-937 [nTPM]":"9.7","Cell RNA - WM-115 [nTPM]":"17.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"0.9","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"1.0","Blood RNA - memory CD8 T-cell [nTPM]":"1.6","Blood RNA - myeloid DC [nTPM]":"1.3","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.1","Blood RNA - naive CD8 T-cell [nTPM]":"1.4","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.9","Blood RNA - non-classical monocyte [nTPM]":"0.7","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"1.8","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"6.3","Brain RNA - basal ganglia [nTPM]":"6.5","Brain RNA - cerebellum [nTPM]":"7.1","Brain RNA - cerebral cortex [nTPM]":"7.8","Brain RNA - hippocampal formation [nTPM]":"6.8","Brain RNA - hypothalamus [nTPM]":"6.7","Brain RNA - medulla oblongata [nTPM]":"6.9","Brain RNA - midbrain [nTPM]":"6.9","Brain RNA - pons [nTPM]":"7.2","Brain RNA - spinal cord [nTPM]":"7.1","Brain RNA - thalamus [nTPM]":"6.4","Brain RNA - white matter [nTPM]":"6.8","Single Cell Type RNA - Adipocytes [nTPM]":"6.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.6","Single Cell Type RNA - Astrocytes [nTPM]":"12.4","Single Cell Type RNA - B-cells [nTPM]":"1.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"71.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"81.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"46.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"50.7","Single Cell Type RNA - Bipolar cells [nTPM]":"33.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"41.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"20.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"18.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"21.0","Single Cell Type RNA - dendritic cells [nTPM]":"3.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"11.1","Single Cell Type RNA - Early spermatids [nTPM]":"8.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.9","Single Cell Type RNA - Endothelial cells [nTPM]":"11.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"8.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.8","Single Cell Type RNA - Fibroblasts [nTPM]":"25.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.7","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"19.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.4","Single Cell Type RNA - Hepatocytes [nTPM]":"2.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.4","Single Cell Type RNA - Horizontal cells [nTPM]":"32.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.5","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"2.2","Single Cell Type RNA - Langerhans cells [nTPM]":"12.2","Single Cell Type RNA - Late spermatids [nTPM]":"7.0","Single Cell Type RNA - Leydig cells [nTPM]":"21.8","Single Cell Type RNA - Macrophages [nTPM]":"2.9","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"5.7","Single Cell Type RNA - Muller glia cells [nTPM]":"38.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.5","Single Cell Type RNA - Paneth cells [nTPM]":"1.9","Single Cell Type RNA - Peritubular cells [nTPM]":"21.4","Single Cell Type RNA - Plasma cells [nTPM]":"3.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"36.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"160.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"33.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.6","Single Cell Type RNA - Spermatocytes [nTPM]":"33.3","Single Cell Type RNA - Spermatogonia [nTPM]":"22.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"30.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"45.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.1","Single Cell Type RNA - T-cells [nTPM]":"4.2","Single Cell Type RNA - Theca cells [nTPM]":"39.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.3","Single Cell Type RNA - Urothelial cells [nTPM]":"29.2"},{"Gene":"TMEM38B","Gene synonym":["bA219P18.1","C9orf87","D4Ertd89e","FLJ10493","TRIC-B"],"Ensembl":"ENSG00000095209","Gene description":"Transmembrane protein 38B","Uniprot":["Q9NVV0"],"Chromosome":"9","Position":"105694541-105776629","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel"],"Disease involvement":["Osteogenesis imperfecta"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"77.4","tongue":"62.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"267.0","Late spermatids":"488.4","Spermatocytes":"157.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018465"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018465":"AB_1858116"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.96e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.6","Tissue RNA - adrenal gland [nTPM]":"14.0","Tissue RNA - amygdala [nTPM]":"6.2","Tissue RNA - appendix [nTPM]":"7.1","Tissue RNA - basal ganglia [nTPM]":"11.6","Tissue RNA - bone marrow [nTPM]":"19.1","Tissue RNA - breast [nTPM]":"4.7","Tissue RNA - cerebellum [nTPM]":"19.5","Tissue RNA - cerebral cortex [nTPM]":"9.2","Tissue RNA - cervix [nTPM]":"7.6","Tissue RNA - choroid plexus [nTPM]":"6.3","Tissue RNA - colon [nTPM]":"12.5","Tissue RNA - duodenum [nTPM]":"6.4","Tissue RNA - endometrium 1 [nTPM]":"8.3","Tissue RNA - epididymis [nTPM]":"17.3","Tissue RNA - esophagus [nTPM]":"7.2","Tissue RNA - fallopian tube [nTPM]":"7.2","Tissue RNA - gallbladder [nTPM]":"6.8","Tissue RNA - heart muscle [nTPM]":"30.7","Tissue RNA - hippocampal formation [nTPM]":"7.4","Tissue RNA - hypothalamus [nTPM]":"12.9","Tissue RNA - kidney [nTPM]":"29.2","Tissue RNA - liver [nTPM]":"15.3","Tissue RNA - lung [nTPM]":"5.7","Tissue RNA - lymph node [nTPM]":"8.1","Tissue RNA - medulla oblongata [nTPM]":"8.3","Tissue RNA - midbrain [nTPM]":"8.4","Tissue RNA - ovary [nTPM]":"18.3","Tissue RNA - pancreas [nTPM]":"4.9","Tissue RNA - parathyroid gland [nTPM]":"9.2","Tissue RNA - pituitary gland [nTPM]":"5.8","Tissue RNA - placenta [nTPM]":"4.6","Tissue RNA - pons [nTPM]":"10.6","Tissue RNA - prostate [nTPM]":"8.0","Tissue RNA - rectum [nTPM]":"11.8","Tissue RNA - retina [nTPM]":"10.4","Tissue RNA - salivary gland [nTPM]":"4.0","Tissue RNA - seminal vesicle [nTPM]":"6.8","Tissue RNA - skeletal muscle [nTPM]":"77.4","Tissue RNA - skin 1 [nTPM]":"6.0","Tissue RNA - small intestine [nTPM]":"10.7","Tissue RNA - smooth muscle [nTPM]":"8.1","Tissue RNA - spinal cord [nTPM]":"5.9","Tissue RNA - spleen [nTPM]":"6.3","Tissue RNA - stomach 1 [nTPM]":"6.7","Tissue RNA - testis [nTPM]":"28.6","Tissue RNA - thalamus [nTPM]":"9.0","Tissue RNA - thymus [nTPM]":"4.9","Tissue RNA - thyroid gland [nTPM]":"28.8","Tissue RNA - tongue [nTPM]":"62.1","Tissue RNA - tonsil [nTPM]":"5.1","Tissue RNA - urinary bladder [nTPM]":"5.0","Tissue RNA - vagina [nTPM]":"4.0","Tissue RNA - white matter [nTPM]":"19.6","Cell RNA - A-431 [nTPM]":"16.7","Cell RNA - A549 [nTPM]":"25.6","Cell RNA - AF22 [nTPM]":"19.6","Cell RNA - AN3-CA [nTPM]":"30.9","Cell RNA - ASC diff [nTPM]":"110.5","Cell RNA - ASC TERT1 [nTPM]":"24.3","Cell RNA - BEWO [nTPM]":"40.8","Cell RNA - BJ [nTPM]":"23.4","Cell RNA - BJ hTERT+ [nTPM]":"15.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"22.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.3","Cell RNA - CACO-2 [nTPM]":"40.0","Cell RNA - CAPAN-2 [nTPM]":"22.5","Cell RNA - Daudi [nTPM]":"38.4","Cell RNA - EFO-21 [nTPM]":"11.8","Cell RNA - fHDF\/TERT166 [nTPM]":"8.5","Cell RNA - GAMG [nTPM]":"36.4","Cell RNA - HaCaT [nTPM]":"11.6","Cell RNA - HAP1 [nTPM]":"28.4","Cell RNA - HBEC3-KT [nTPM]":"13.5","Cell RNA - HBF TERT88 [nTPM]":"24.4","Cell RNA - HDLM-2 [nTPM]":"29.0","Cell RNA - HEK 293 [nTPM]":"37.8","Cell RNA - HEL [nTPM]":"15.8","Cell RNA - HeLa [nTPM]":"16.2","Cell RNA - Hep G2 [nTPM]":"24.7","Cell RNA - HHSteC [nTPM]":"15.1","Cell RNA - HL-60 [nTPM]":"48.1","Cell RNA - HMC-1 [nTPM]":"32.7","Cell RNA - HSkMC [nTPM]":"23.0","Cell RNA - hTCEpi [nTPM]":"11.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.5","Cell RNA - hTERT-HME1 [nTPM]":"21.6","Cell RNA - hTERT-RPE1 [nTPM]":"7.1","Cell RNA - HUVEC TERT2 [nTPM]":"9.1","Cell RNA - JURKAT [nTPM]":"26.6","Cell RNA - K-562 [nTPM]":"84.3","Cell RNA - Karpas-707 [nTPM]":"33.2","Cell RNA - LHCN-M2 [nTPM]":"14.0","Cell RNA - MCF7 [nTPM]":"46.4","Cell RNA - MOLT-4 [nTPM]":"33.6","Cell RNA - NB-4 [nTPM]":"14.5","Cell RNA - NTERA-2 [nTPM]":"15.1","Cell RNA - OE19 [nTPM]":"48.7","Cell RNA - PC-3 [nTPM]":"27.1","Cell RNA - REH [nTPM]":"22.3","Cell RNA - RH-30 [nTPM]":"61.4","Cell RNA - RPMI-8226 [nTPM]":"18.4","Cell RNA - RPTEC TERT1 [nTPM]":"10.3","Cell RNA - RT4 [nTPM]":"13.2","Cell RNA - SCLC-21H [nTPM]":"34.1","Cell RNA - SH-SY5Y [nTPM]":"8.3","Cell RNA - SiHa [nTPM]":"24.2","Cell RNA - SK-BR-3 [nTPM]":"39.4","Cell RNA - SK-MEL-30 [nTPM]":"17.9","Cell RNA - SuSa [nTPM]":"13.0","Cell RNA - T-47d [nTPM]":"49.2","Cell RNA - THP-1 [nTPM]":"33.5","Cell RNA - TIME [nTPM]":"4.9","Cell RNA - U-138 MG [nTPM]":"20.5","Cell RNA - U-2 OS [nTPM]":"20.2","Cell RNA - U-2197 [nTPM]":"78.9","Cell RNA - U-251 MG [nTPM]":"24.7","Cell RNA - U-266\/70 [nTPM]":"40.7","Cell RNA - U-266\/84 [nTPM]":"109.8","Cell RNA - U-698 [nTPM]":"19.1","Cell RNA - U-87 MG [nTPM]":"38.2","Cell RNA - U-937 [nTPM]":"52.2","Cell RNA - WM-115 [nTPM]":"41.7","Blood RNA - basophil [nTPM]":"15.6","Blood RNA - classical monocyte [nTPM]":"20.2","Blood RNA - eosinophil [nTPM]":"53.8","Blood RNA - gdT-cell [nTPM]":"13.2","Blood RNA - intermediate monocyte [nTPM]":"29.6","Blood RNA - MAIT T-cell [nTPM]":"17.7","Blood RNA - memory B-cell [nTPM]":"56.6","Blood RNA - memory CD4 T-cell [nTPM]":"18.3","Blood RNA - memory CD8 T-cell [nTPM]":"15.8","Blood RNA - myeloid DC [nTPM]":"23.3","Blood RNA - naive B-cell [nTPM]":"56.6","Blood RNA - naive CD4 T-cell [nTPM]":"38.9","Blood RNA - naive CD8 T-cell [nTPM]":"24.9","Blood RNA - neutrophil [nTPM]":"3.1","Blood RNA - NK-cell [nTPM]":"28.2","Blood RNA - non-classical monocyte [nTPM]":"26.8","Blood RNA - plasmacytoid DC [nTPM]":"51.7","Blood RNA - T-reg [nTPM]":"18.0","Blood RNA - total PBMC [nTPM]":"24.2","Brain RNA - amygdala [nTPM]":"6.2","Brain RNA - basal ganglia [nTPM]":"11.6","Brain RNA - cerebellum [nTPM]":"19.5","Brain RNA - cerebral cortex [nTPM]":"9.2","Brain RNA - hippocampal formation [nTPM]":"7.4","Brain RNA - hypothalamus [nTPM]":"12.9","Brain RNA - medulla oblongata [nTPM]":"8.3","Brain RNA - midbrain [nTPM]":"8.4","Brain RNA - pons [nTPM]":"10.6","Brain RNA - spinal cord [nTPM]":"5.9","Brain RNA - thalamus [nTPM]":"9.0","Brain RNA - white matter [nTPM]":"19.6","Single Cell Type RNA - Adipocytes [nTPM]":"9.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.7","Single Cell Type RNA - Astrocytes [nTPM]":"7.5","Single Cell Type RNA - B-cells [nTPM]":"27.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Bipolar cells [nTPM]":"12.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"55.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"8.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.0","Single Cell Type RNA - dendritic cells [nTPM]":"16.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"19.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"66.5","Single Cell Type RNA - Ductal cells [nTPM]":"8.9","Single Cell Type RNA - Early spermatids [nTPM]":"267.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.2","Single Cell Type RNA - Endothelial cells [nTPM]":"9.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"31.8","Single Cell Type RNA - Erythroid cells [nTPM]":"7.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.0","Single Cell Type RNA - Fibroblasts [nTPM]":"24.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.0","Single Cell Type RNA - granulocytes [nTPM]":"15.8","Single Cell Type RNA - Granulosa cells [nTPM]":"11.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"24.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.9","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"28.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.9","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"7.9","Single Cell Type RNA - Langerhans cells [nTPM]":"33.2","Single Cell Type RNA - Late spermatids [nTPM]":"488.4","Single Cell Type RNA - Leydig cells [nTPM]":"85.1","Single Cell Type RNA - Macrophages [nTPM]":"21.4","Single Cell Type RNA - Melanocytes [nTPM]":"32.0","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"18.3","Single Cell Type RNA - Muller glia cells [nTPM]":"30.6","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"65.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"30.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.3","Single Cell Type RNA - Paneth cells [nTPM]":"12.2","Single Cell Type RNA - Peritubular cells [nTPM]":"44.8","Single Cell Type RNA - Plasma cells [nTPM]":"20.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"55.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"47.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.3","Single Cell Type RNA - Sertoli cells [nTPM]":"118.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"58.1","Single Cell Type RNA - Spermatocytes [nTPM]":"157.8","Single Cell Type RNA - Spermatogonia [nTPM]":"47.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"32.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"21.2","Single Cell Type RNA - T-cells [nTPM]":"13.8","Single Cell Type RNA - Theca cells [nTPM]":"39.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.0","Single Cell Type RNA - Urothelial cells [nTPM]":"20.2"},{"Gene":"TMEM67","Gene synonym":["JBTS6","MGC26979","MKS3","NPHP11"],"Ensembl":"ENSG00000164953","Gene description":"Transmembrane protein 67","Uniprot":["Q5HYA8"],"Chromosome":"8","Position":"93754844-93819234","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":null,"Disease involvement":["Bardet-Biedl syndrome","Ciliopathy","Deafness","Disease variant","Joubert syndrome","Meckel syndrome","Mental retardation","Nephronophthisis","Obesity","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"66.7","Excitatory neurons":"59.8","Respiratory ciliated cells":"95.8","Rod photoreceptor cells":"83.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.62e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Tissue RNA - adipose tissue [nTPM]":"2.4","Tissue RNA - adrenal gland [nTPM]":"2.5","Tissue RNA - amygdala [nTPM]":"1.7","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"2.7","Tissue RNA - bone marrow [nTPM]":"1.4","Tissue RNA - breast [nTPM]":"3.5","Tissue RNA - cerebellum [nTPM]":"2.8","Tissue RNA - cerebral cortex [nTPM]":"2.7","Tissue RNA - cervix [nTPM]":"3.6","Tissue RNA - choroid plexus [nTPM]":"10.3","Tissue RNA - colon [nTPM]":"2.1","Tissue RNA - duodenum [nTPM]":"1.4","Tissue RNA - endometrium 1 [nTPM]":"4.2","Tissue RNA - epididymis [nTPM]":"6.3","Tissue RNA - esophagus [nTPM]":"1.8","Tissue RNA - fallopian tube [nTPM]":"13.3","Tissue RNA - gallbladder [nTPM]":"2.8","Tissue RNA - heart muscle [nTPM]":"5.0","Tissue RNA - hippocampal formation [nTPM]":"2.5","Tissue RNA - hypothalamus [nTPM]":"3.0","Tissue RNA - kidney [nTPM]":"3.1","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"3.6","Tissue RNA - lymph node [nTPM]":"1.4","Tissue RNA - medulla oblongata [nTPM]":"6.5","Tissue RNA - midbrain [nTPM]":"6.8","Tissue RNA - ovary [nTPM]":"4.2","Tissue RNA - pancreas [nTPM]":"2.6","Tissue RNA - parathyroid gland [nTPM]":"4.7","Tissue RNA - pituitary gland [nTPM]":"5.8","Tissue RNA - placenta [nTPM]":"2.1","Tissue RNA - pons [nTPM]":"3.1","Tissue RNA - prostate [nTPM]":"2.8","Tissue RNA - rectum [nTPM]":"2.2","Tissue RNA - retina [nTPM]":"6.1","Tissue RNA - salivary gland [nTPM]":"1.9","Tissue RNA - seminal vesicle [nTPM]":"3.2","Tissue RNA - skeletal muscle [nTPM]":"1.2","Tissue RNA - skin 1 [nTPM]":"3.7","Tissue RNA - small intestine [nTPM]":"1.3","Tissue RNA - smooth muscle [nTPM]":"2.4","Tissue RNA - spinal cord [nTPM]":"3.5","Tissue RNA - spleen [nTPM]":"1.9","Tissue RNA - stomach 1 [nTPM]":"2.0","Tissue RNA - testis [nTPM]":"6.8","Tissue RNA - thalamus [nTPM]":"3.1","Tissue RNA - thymus [nTPM]":"1.4","Tissue RNA - thyroid gland [nTPM]":"6.0","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"1.7","Tissue RNA - urinary bladder [nTPM]":"2.5","Tissue RNA - vagina [nTPM]":"2.2","Tissue RNA - white matter [nTPM]":"3.9","Cell RNA - A-431 [nTPM]":"5.8","Cell RNA - A549 [nTPM]":"3.7","Cell RNA - AF22 [nTPM]":"5.2","Cell RNA - AN3-CA [nTPM]":"4.1","Cell RNA - ASC diff [nTPM]":"4.4","Cell RNA - ASC TERT1 [nTPM]":"9.8","Cell RNA - BEWO [nTPM]":"3.1","Cell RNA - BJ [nTPM]":"3.3","Cell RNA - BJ hTERT+ [nTPM]":"5.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.5","Cell RNA - CACO-2 [nTPM]":"2.1","Cell RNA - CAPAN-2 [nTPM]":"13.0","Cell RNA - Daudi [nTPM]":"1.5","Cell RNA - EFO-21 [nTPM]":"6.9","Cell RNA - fHDF\/TERT166 [nTPM]":"3.6","Cell RNA - GAMG [nTPM]":"6.9","Cell RNA - HaCaT [nTPM]":"5.9","Cell RNA - HAP1 [nTPM]":"1.9","Cell RNA - HBEC3-KT [nTPM]":"3.3","Cell RNA - HBF TERT88 [nTPM]":"5.6","Cell RNA - HDLM-2 [nTPM]":"1.1","Cell RNA - HEK 293 [nTPM]":"4.3","Cell RNA - HEL [nTPM]":"3.6","Cell RNA - HeLa [nTPM]":"4.8","Cell RNA - Hep G2 [nTPM]":"1.8","Cell RNA - HHSteC [nTPM]":"4.0","Cell RNA - HL-60 [nTPM]":"2.7","Cell RNA - HMC-1 [nTPM]":"1.5","Cell RNA - HSkMC [nTPM]":"4.2","Cell RNA - hTCEpi [nTPM]":"3.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.8","Cell RNA - hTERT-HME1 [nTPM]":"3.0","Cell RNA - hTERT-RPE1 [nTPM]":"7.1","Cell RNA - HUVEC TERT2 [nTPM]":"4.0","Cell RNA - JURKAT [nTPM]":"6.1","Cell RNA - K-562 [nTPM]":"2.5","Cell RNA - Karpas-707 [nTPM]":"0.9","Cell RNA - LHCN-M2 [nTPM]":"4.0","Cell RNA - MCF7 [nTPM]":"1.4","Cell RNA - MOLT-4 [nTPM]":"4.5","Cell RNA - NB-4 [nTPM]":"2.0","Cell RNA - NTERA-2 [nTPM]":"4.3","Cell RNA - OE19 [nTPM]":"2.3","Cell RNA - PC-3 [nTPM]":"3.4","Cell RNA - REH [nTPM]":"1.6","Cell RNA - RH-30 [nTPM]":"1.7","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"4.7","Cell RNA - RT4 [nTPM]":"2.5","Cell RNA - SCLC-21H [nTPM]":"3.4","Cell RNA - SH-SY5Y [nTPM]":"5.7","Cell RNA - SiHa [nTPM]":"3.3","Cell RNA - SK-BR-3 [nTPM]":"0.9","Cell RNA - SK-MEL-30 [nTPM]":"5.6","Cell RNA - SuSa [nTPM]":"4.6","Cell RNA - T-47d [nTPM]":"6.8","Cell RNA - THP-1 [nTPM]":"1.4","Cell RNA - TIME [nTPM]":"2.1","Cell RNA - U-138 MG [nTPM]":"4.1","Cell RNA - U-2 OS [nTPM]":"1.7","Cell RNA - U-2197 [nTPM]":"5.7","Cell RNA - U-251 MG [nTPM]":"3.0","Cell RNA - U-266\/70 [nTPM]":"1.8","Cell RNA - U-266\/84 [nTPM]":"5.5","Cell RNA - U-698 [nTPM]":"1.6","Cell RNA - U-87 MG [nTPM]":"7.4","Cell RNA - U-937 [nTPM]":"0.8","Cell RNA - WM-115 [nTPM]":"3.9","Blood RNA - basophil [nTPM]":"1.7","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"1.2","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"1.3","Blood RNA - myeloid DC [nTPM]":"1.0","Blood RNA - naive B-cell [nTPM]":"1.5","Blood RNA - naive CD4 T-cell [nTPM]":"1.5","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"1.7","Brain RNA - basal ganglia [nTPM]":"2.7","Brain RNA - cerebellum [nTPM]":"2.8","Brain RNA - cerebral cortex [nTPM]":"2.7","Brain RNA - hippocampal formation [nTPM]":"2.5","Brain RNA - hypothalamus [nTPM]":"3.0","Brain RNA - medulla oblongata [nTPM]":"6.5","Brain RNA - midbrain [nTPM]":"6.8","Brain RNA - pons [nTPM]":"3.1","Brain RNA - spinal cord [nTPM]":"3.5","Brain RNA - thalamus [nTPM]":"3.1","Brain RNA - white matter [nTPM]":"3.9","Single Cell Type RNA - Adipocytes [nTPM]":"5.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.7","Single Cell Type RNA - Astrocytes [nTPM]":"27.4","Single Cell Type RNA - B-cells [nTPM]":"6.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"14.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"31.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"12.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"66.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - dendritic cells [nTPM]":"5.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.4","Single Cell Type RNA - Early spermatids [nTPM]":"24.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"50.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.1","Single Cell Type RNA - Endothelial cells [nTPM]":"6.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.0","Single Cell Type RNA - Erythroid cells [nTPM]":"4.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"59.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.6","Single Cell Type RNA - Fibroblasts [nTPM]":"9.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.9","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"16.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.0","Single Cell Type RNA - Hepatocytes [nTPM]":"1.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.2","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"34.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.4","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"2.9","Single Cell Type RNA - Langerhans cells [nTPM]":"2.6","Single Cell Type RNA - Late spermatids [nTPM]":"7.7","Single Cell Type RNA - Leydig cells [nTPM]":"16.1","Single Cell Type RNA - Macrophages [nTPM]":"1.8","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"1.5","Single Cell Type RNA - Muller glia cells [nTPM]":"9.3","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.5","Single Cell Type RNA - Peritubular cells [nTPM]":"10.5","Single Cell Type RNA - Plasma cells [nTPM]":"2.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"95.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"83.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.9","Single Cell Type RNA - Spermatocytes [nTPM]":"47.6","Single Cell Type RNA - Spermatogonia [nTPM]":"16.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.3","Single Cell Type RNA - T-cells [nTPM]":"5.6","Single Cell Type RNA - Theca cells [nTPM]":"13.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.8","Single Cell Type RNA - Urothelial cells [nTPM]":"1.6"},{"Gene":"TMEM70","Gene synonym":["FLJ20533"],"Ensembl":"ENSG00000175606","Gene description":"Transmembrane protein 70","Uniprot":["Q9BUB7"],"Chromosome":"8","Position":"73972437-73982783","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"skeletal muscle":"100.7"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SK-BR-3":"78.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023187","CAB034226"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB034226":"AB_2205189","HPA023187":"AB_2671101"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Tissue RNA - adipose tissue [nTPM]":"18.1","Tissue RNA - adrenal gland [nTPM]":"18.2","Tissue RNA - amygdala [nTPM]":"9.2","Tissue RNA - appendix [nTPM]":"9.8","Tissue RNA - basal ganglia [nTPM]":"9.7","Tissue RNA - bone marrow [nTPM]":"10.4","Tissue RNA - breast [nTPM]":"11.3","Tissue RNA - cerebellum [nTPM]":"10.5","Tissue RNA - cerebral cortex [nTPM]":"12.3","Tissue RNA - cervix [nTPM]":"8.0","Tissue RNA - choroid plexus [nTPM]":"9.5","Tissue RNA - colon [nTPM]":"12.6","Tissue RNA - duodenum [nTPM]":"5.8","Tissue RNA - endometrium 1 [nTPM]":"8.9","Tissue RNA - epididymis [nTPM]":"10.6","Tissue RNA - esophagus [nTPM]":"9.3","Tissue RNA - fallopian tube [nTPM]":"11.3","Tissue RNA - gallbladder [nTPM]":"8.9","Tissue RNA - heart muscle [nTPM]":"19.3","Tissue RNA - hippocampal formation [nTPM]":"10.3","Tissue RNA - hypothalamus [nTPM]":"10.2","Tissue RNA - kidney [nTPM]":"12.0","Tissue RNA - liver [nTPM]":"24.4","Tissue RNA - lung [nTPM]":"9.0","Tissue RNA - lymph node [nTPM]":"10.1","Tissue RNA - medulla oblongata [nTPM]":"9.6","Tissue RNA - midbrain [nTPM]":"9.1","Tissue RNA - ovary [nTPM]":"10.5","Tissue RNA - pancreas [nTPM]":"25.0","Tissue RNA - parathyroid gland [nTPM]":"8.3","Tissue RNA - pituitary gland [nTPM]":"7.6","Tissue RNA - placenta [nTPM]":"10.3","Tissue RNA - pons [nTPM]":"10.1","Tissue RNA - prostate [nTPM]":"7.4","Tissue RNA - rectum [nTPM]":"9.7","Tissue RNA - retina [nTPM]":"6.1","Tissue RNA - salivary gland [nTPM]":"9.9","Tissue RNA - seminal vesicle [nTPM]":"5.9","Tissue RNA - skeletal muscle [nTPM]":"100.7","Tissue RNA - skin 1 [nTPM]":"7.7","Tissue RNA - small intestine [nTPM]":"9.5","Tissue RNA - smooth muscle [nTPM]":"9.1","Tissue RNA - spinal cord [nTPM]":"9.5","Tissue RNA - spleen [nTPM]":"9.6","Tissue RNA - stomach 1 [nTPM]":"17.8","Tissue RNA - testis [nTPM]":"9.8","Tissue RNA - thalamus [nTPM]":"9.5","Tissue RNA - thymus [nTPM]":"11.0","Tissue RNA - thyroid gland [nTPM]":"6.0","Tissue RNA - tongue [nTPM]":"20.5","Tissue RNA - tonsil [nTPM]":"10.3","Tissue RNA - urinary bladder [nTPM]":"11.3","Tissue RNA - vagina [nTPM]":"7.4","Tissue RNA - white matter [nTPM]":"10.1","Cell RNA - A-431 [nTPM]":"21.2","Cell RNA - A549 [nTPM]":"16.4","Cell RNA - AF22 [nTPM]":"13.1","Cell RNA - AN3-CA [nTPM]":"13.8","Cell RNA - ASC diff [nTPM]":"14.9","Cell RNA - ASC TERT1 [nTPM]":"12.7","Cell RNA - BEWO [nTPM]":"13.6","Cell RNA - BJ [nTPM]":"17.6","Cell RNA - BJ hTERT+ [nTPM]":"15.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.3","Cell RNA - CACO-2 [nTPM]":"15.8","Cell RNA - CAPAN-2 [nTPM]":"11.9","Cell RNA - Daudi [nTPM]":"28.4","Cell RNA - EFO-21 [nTPM]":"15.0","Cell RNA - fHDF\/TERT166 [nTPM]":"12.0","Cell RNA - GAMG [nTPM]":"16.4","Cell RNA - HaCaT [nTPM]":"19.1","Cell RNA - HAP1 [nTPM]":"24.9","Cell RNA - HBEC3-KT [nTPM]":"16.8","Cell RNA - HBF TERT88 [nTPM]":"21.4","Cell RNA - HDLM-2 [nTPM]":"18.9","Cell RNA - HEK 293 [nTPM]":"17.5","Cell RNA - HEL [nTPM]":"28.3","Cell RNA - HeLa [nTPM]":"10.0","Cell RNA - Hep G2 [nTPM]":"21.2","Cell RNA - HHSteC [nTPM]":"14.7","Cell RNA - HL-60 [nTPM]":"15.5","Cell RNA - HMC-1 [nTPM]":"14.5","Cell RNA - HSkMC [nTPM]":"11.8","Cell RNA - hTCEpi [nTPM]":"15.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.2","Cell RNA - hTERT-HME1 [nTPM]":"6.4","Cell RNA - hTERT-RPE1 [nTPM]":"7.3","Cell RNA - HUVEC TERT2 [nTPM]":"16.4","Cell RNA - JURKAT [nTPM]":"14.2","Cell RNA - K-562 [nTPM]":"22.0","Cell RNA - Karpas-707 [nTPM]":"13.5","Cell RNA - LHCN-M2 [nTPM]":"20.5","Cell RNA - MCF7 [nTPM]":"15.9","Cell RNA - MOLT-4 [nTPM]":"35.8","Cell RNA - NB-4 [nTPM]":"29.6","Cell RNA - NTERA-2 [nTPM]":"12.3","Cell RNA - OE19 [nTPM]":"26.6","Cell RNA - PC-3 [nTPM]":"20.6","Cell RNA - REH [nTPM]":"25.4","Cell RNA - RH-30 [nTPM]":"12.8","Cell RNA - RPMI-8226 [nTPM]":"24.2","Cell RNA - RPTEC TERT1 [nTPM]":"20.5","Cell RNA - RT4 [nTPM]":"20.0","Cell RNA - SCLC-21H [nTPM]":"29.7","Cell RNA - SH-SY5Y [nTPM]":"13.1","Cell RNA - SiHa [nTPM]":"11.0","Cell RNA - SK-BR-3 [nTPM]":"78.0","Cell RNA - SK-MEL-30 [nTPM]":"23.3","Cell RNA - SuSa [nTPM]":"10.2","Cell RNA - T-47d [nTPM]":"16.0","Cell RNA - THP-1 [nTPM]":"14.1","Cell RNA - TIME [nTPM]":"10.6","Cell RNA - U-138 MG [nTPM]":"11.1","Cell RNA - U-2 OS [nTPM]":"13.7","Cell RNA - U-2197 [nTPM]":"20.7","Cell RNA - U-251 MG [nTPM]":"16.9","Cell RNA - U-266\/70 [nTPM]":"19.9","Cell RNA - U-266\/84 [nTPM]":"18.7","Cell RNA - U-698 [nTPM]":"28.1","Cell RNA - U-87 MG [nTPM]":"16.4","Cell RNA - U-937 [nTPM]":"12.1","Cell RNA - WM-115 [nTPM]":"12.5","Blood RNA - basophil [nTPM]":"6.3","Blood RNA - classical monocyte [nTPM]":"9.1","Blood RNA - eosinophil [nTPM]":"6.7","Blood RNA - gdT-cell [nTPM]":"8.0","Blood RNA - intermediate monocyte [nTPM]":"10.2","Blood RNA - MAIT T-cell [nTPM]":"9.1","Blood RNA - memory B-cell [nTPM]":"17.7","Blood RNA - memory CD4 T-cell [nTPM]":"9.0","Blood RNA - memory CD8 T-cell [nTPM]":"9.3","Blood RNA - myeloid DC [nTPM]":"9.6","Blood RNA - naive B-cell [nTPM]":"10.9","Blood RNA - naive CD4 T-cell [nTPM]":"10.3","Blood RNA - naive CD8 T-cell [nTPM]":"9.6","Blood RNA - neutrophil [nTPM]":"6.7","Blood RNA - NK-cell [nTPM]":"5.8","Blood RNA - non-classical monocyte [nTPM]":"7.9","Blood RNA - plasmacytoid DC [nTPM]":"11.0","Blood RNA - T-reg [nTPM]":"7.9","Blood RNA - total PBMC [nTPM]":"12.0","Brain RNA - amygdala [nTPM]":"9.2","Brain RNA - basal ganglia [nTPM]":"9.7","Brain RNA - cerebellum [nTPM]":"10.5","Brain RNA - cerebral cortex [nTPM]":"12.3","Brain RNA - hippocampal formation [nTPM]":"10.3","Brain RNA - hypothalamus [nTPM]":"10.2","Brain RNA - medulla oblongata [nTPM]":"9.6","Brain RNA - midbrain [nTPM]":"9.1","Brain RNA - pons [nTPM]":"10.1","Brain RNA - spinal cord [nTPM]":"9.5","Brain RNA - thalamus [nTPM]":"9.5","Brain RNA - white matter [nTPM]":"10.1","Single Cell Type RNA - Adipocytes [nTPM]":"136.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"30.1","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"37.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"67.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"43.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"54.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"23.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"22.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"46.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"35.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"71.2","Single Cell Type RNA - dendritic cells [nTPM]":"48.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"69.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"66.5","Single Cell Type RNA - Ductal cells [nTPM]":"36.6","Single Cell Type RNA - Early spermatids [nTPM]":"20.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"40.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.2","Single Cell Type RNA - Endothelial cells [nTPM]":"96.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.8","Single Cell Type RNA - Erythroid cells [nTPM]":"26.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"63.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"59.6","Single Cell Type RNA - Fibroblasts [nTPM]":"50.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.1","Single Cell Type RNA - granulocytes [nTPM]":"39.9","Single Cell Type RNA - Granulosa cells [nTPM]":"17.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.5","Single Cell Type RNA - Hepatocytes [nTPM]":"50.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"132.4","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.7","Single Cell Type RNA - Ionocytes [nTPM]":"42.7","Single Cell Type RNA - Kupffer cells [nTPM]":"70.0","Single Cell Type RNA - Langerhans cells [nTPM]":"74.5","Single Cell Type RNA - Late spermatids [nTPM]":"12.1","Single Cell Type RNA - Leydig cells [nTPM]":"29.8","Single Cell Type RNA - Macrophages [nTPM]":"73.2","Single Cell Type RNA - Melanocytes [nTPM]":"40.9","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"38.9","Single Cell Type RNA - Muller glia cells [nTPM]":"23.1","Single Cell Type RNA - NK-cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"43.6","Single Cell Type RNA - Paneth cells [nTPM]":"37.9","Single Cell Type RNA - Peritubular cells [nTPM]":"29.0","Single Cell Type RNA - Plasma cells [nTPM]":"68.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"42.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"28.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"75.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"58.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.5","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"61.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"40.8","Single Cell Type RNA - Spermatocytes [nTPM]":"70.6","Single Cell Type RNA - Spermatogonia [nTPM]":"29.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"59.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"70.3","Single Cell Type RNA - T-cells [nTPM]":"39.8","Single Cell Type RNA - Theca cells [nTPM]":"52.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"34.1","Single Cell Type RNA - Urothelial cells [nTPM]":"26.2"},{"Gene":"TMEM94","Gene synonym":["KIAA0195"],"Ensembl":"ENSG00000177728","Gene description":"Transmembrane protein 94","Uniprot":["Q12767"],"Chromosome":"17","Position":"75441159-75500452","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"43.0","Granulosa cells":"41.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008423","HPA050660"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 23: AN3-CA - Transcription regulation","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA008423":"AB_1852283","HPA050660":"AB_2681207"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.26e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Tissue RNA - adipose tissue [nTPM]":"21.3","Tissue RNA - adrenal gland [nTPM]":"55.9","Tissue RNA - amygdala [nTPM]":"50.3","Tissue RNA - appendix [nTPM]":"13.9","Tissue RNA - basal ganglia [nTPM]":"46.4","Tissue RNA - bone marrow [nTPM]":"18.4","Tissue RNA - breast [nTPM]":"21.7","Tissue RNA - cerebellum [nTPM]":"27.7","Tissue RNA - cerebral cortex [nTPM]":"54.9","Tissue RNA - cervix [nTPM]":"21.9","Tissue RNA - choroid plexus [nTPM]":"30.5","Tissue RNA - colon [nTPM]":"25.1","Tissue RNA - duodenum [nTPM]":"18.8","Tissue RNA - endometrium 1 [nTPM]":"24.4","Tissue RNA - epididymis [nTPM]":"5.4","Tissue RNA - esophagus [nTPM]":"21.1","Tissue RNA - fallopian tube [nTPM]":"30.7","Tissue RNA - gallbladder [nTPM]":"15.8","Tissue RNA - heart muscle [nTPM]":"27.8","Tissue RNA - hippocampal formation [nTPM]":"40.7","Tissue RNA - hypothalamus [nTPM]":"31.5","Tissue RNA - kidney [nTPM]":"29.7","Tissue RNA - liver [nTPM]":"20.2","Tissue RNA - lung [nTPM]":"25.6","Tissue RNA - lymph node [nTPM]":"14.1","Tissue RNA - medulla oblongata [nTPM]":"40.1","Tissue RNA - midbrain [nTPM]":"36.8","Tissue RNA - ovary [nTPM]":"27.7","Tissue RNA - pancreas [nTPM]":"23.7","Tissue RNA - parathyroid gland [nTPM]":"20.3","Tissue RNA - pituitary gland [nTPM]":"30.1","Tissue RNA - placenta [nTPM]":"14.2","Tissue RNA - pons [nTPM]":"30.5","Tissue RNA - prostate [nTPM]":"19.9","Tissue RNA - rectum [nTPM]":"13.6","Tissue RNA - retina [nTPM]":"27.7","Tissue RNA - salivary gland [nTPM]":"21.1","Tissue RNA - seminal vesicle [nTPM]":"13.2","Tissue RNA - skeletal muscle [nTPM]":"63.4","Tissue RNA - skin 1 [nTPM]":"22.9","Tissue RNA - small intestine [nTPM]":"28.2","Tissue RNA - smooth muscle [nTPM]":"10.7","Tissue RNA - spinal cord [nTPM]":"34.8","Tissue RNA - spleen [nTPM]":"29.7","Tissue RNA - stomach 1 [nTPM]":"25.0","Tissue RNA - testis [nTPM]":"27.1","Tissue RNA - thalamus [nTPM]":"47.1","Tissue RNA - thymus [nTPM]":"18.0","Tissue RNA - thyroid gland [nTPM]":"27.4","Tissue RNA - tongue [nTPM]":"25.8","Tissue RNA - tonsil [nTPM]":"8.6","Tissue RNA - urinary bladder [nTPM]":"20.5","Tissue RNA - vagina [nTPM]":"15.3","Tissue RNA - white matter [nTPM]":"35.8","Cell RNA - A-431 [nTPM]":"15.3","Cell RNA - A549 [nTPM]":"40.7","Cell RNA - AF22 [nTPM]":"33.6","Cell RNA - AN3-CA [nTPM]":"52.6","Cell RNA - ASC diff [nTPM]":"16.1","Cell RNA - ASC TERT1 [nTPM]":"18.8","Cell RNA - BEWO [nTPM]":"45.6","Cell RNA - BJ [nTPM]":"9.2","Cell RNA - BJ hTERT+ [nTPM]":"20.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.4","Cell RNA - CACO-2 [nTPM]":"13.7","Cell RNA - CAPAN-2 [nTPM]":"22.6","Cell RNA - Daudi [nTPM]":"20.6","Cell RNA - EFO-21 [nTPM]":"30.3","Cell RNA - fHDF\/TERT166 [nTPM]":"15.9","Cell RNA - GAMG [nTPM]":"23.6","Cell RNA - HaCaT [nTPM]":"19.9","Cell RNA - HAP1 [nTPM]":"15.8","Cell RNA - HBEC3-KT [nTPM]":"25.6","Cell RNA - HBF TERT88 [nTPM]":"8.8","Cell RNA - HDLM-2 [nTPM]":"19.4","Cell RNA - HEK 293 [nTPM]":"23.1","Cell RNA - HEL [nTPM]":"22.0","Cell RNA - HeLa [nTPM]":"18.4","Cell RNA - Hep G2 [nTPM]":"22.9","Cell RNA - HHSteC [nTPM]":"21.2","Cell RNA - HL-60 [nTPM]":"23.7","Cell RNA - HMC-1 [nTPM]":"45.2","Cell RNA - HSkMC [nTPM]":"30.9","Cell RNA - hTCEpi [nTPM]":"14.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.0","Cell RNA - hTERT-HME1 [nTPM]":"13.4","Cell RNA - hTERT-RPE1 [nTPM]":"13.9","Cell RNA - HUVEC TERT2 [nTPM]":"28.1","Cell RNA - JURKAT [nTPM]":"18.3","Cell RNA - K-562 [nTPM]":"22.6","Cell RNA - Karpas-707 [nTPM]":"24.4","Cell RNA - LHCN-M2 [nTPM]":"20.7","Cell RNA - MCF7 [nTPM]":"19.1","Cell RNA - MOLT-4 [nTPM]":"53.3","Cell RNA - NB-4 [nTPM]":"18.8","Cell RNA - NTERA-2 [nTPM]":"14.4","Cell RNA - OE19 [nTPM]":"19.3","Cell RNA - PC-3 [nTPM]":"16.2","Cell RNA - REH [nTPM]":"36.2","Cell RNA - RH-30 [nTPM]":"37.2","Cell RNA - RPMI-8226 [nTPM]":"19.2","Cell RNA - RPTEC TERT1 [nTPM]":"16.0","Cell RNA - RT4 [nTPM]":"40.7","Cell RNA - SCLC-21H [nTPM]":"28.1","Cell RNA - SH-SY5Y [nTPM]":"30.5","Cell RNA - SiHa [nTPM]":"10.2","Cell RNA - SK-BR-3 [nTPM]":"47.4","Cell RNA - SK-MEL-30 [nTPM]":"28.7","Cell RNA - SuSa [nTPM]":"25.3","Cell RNA - T-47d [nTPM]":"29.8","Cell RNA - THP-1 [nTPM]":"29.3","Cell RNA - TIME [nTPM]":"16.0","Cell RNA - U-138 MG [nTPM]":"16.5","Cell RNA - U-2 OS [nTPM]":"19.0","Cell RNA - U-2197 [nTPM]":"16.5","Cell RNA - U-251 MG [nTPM]":"13.8","Cell RNA - U-266\/70 [nTPM]":"53.2","Cell RNA - U-266\/84 [nTPM]":"17.2","Cell RNA - U-698 [nTPM]":"12.2","Cell RNA - U-87 MG [nTPM]":"17.2","Cell RNA - U-937 [nTPM]":"23.8","Cell RNA - WM-115 [nTPM]":"20.8","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"2.6","Blood RNA - eosinophil [nTPM]":"3.0","Blood RNA - gdT-cell [nTPM]":"3.5","Blood RNA - intermediate monocyte [nTPM]":"1.6","Blood RNA - MAIT T-cell [nTPM]":"2.6","Blood RNA - memory B-cell [nTPM]":"1.0","Blood RNA - memory CD4 T-cell [nTPM]":"1.6","Blood RNA - memory CD8 T-cell [nTPM]":"2.5","Blood RNA - myeloid DC [nTPM]":"2.5","Blood RNA - naive B-cell [nTPM]":"2.5","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"2.2","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"2.4","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"3.3","Blood RNA - T-reg [nTPM]":"2.1","Blood RNA - total PBMC [nTPM]":"2.9","Brain RNA - amygdala [nTPM]":"50.3","Brain RNA - basal ganglia [nTPM]":"46.4","Brain RNA - cerebellum [nTPM]":"27.7","Brain RNA - cerebral cortex [nTPM]":"54.9","Brain RNA - hippocampal formation [nTPM]":"40.7","Brain RNA - hypothalamus [nTPM]":"31.5","Brain RNA - medulla oblongata [nTPM]":"40.1","Brain RNA - midbrain [nTPM]":"36.8","Brain RNA - pons [nTPM]":"30.5","Brain RNA - spinal cord [nTPM]":"34.8","Brain RNA - thalamus [nTPM]":"47.1","Brain RNA - white matter [nTPM]":"35.8","Single Cell Type RNA - Adipocytes [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"5.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"43.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"6.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.1","Single Cell Type RNA - dendritic cells [nTPM]":"8.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"8.1","Single Cell Type RNA - Early spermatids [nTPM]":"4.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.8","Single Cell Type RNA - Endothelial cells [nTPM]":"8.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.3","Single Cell Type RNA - Erythroid cells [nTPM]":"10.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.0","Single Cell Type RNA - Fibroblasts [nTPM]":"4.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"28.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.6","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"41.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.9","Single Cell Type RNA - Hepatocytes [nTPM]":"8.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.4","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"12.4","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.9","Single Cell Type RNA - Leydig cells [nTPM]":"6.8","Single Cell Type RNA - Macrophages [nTPM]":"8.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"5.6","Single Cell Type RNA - Muller glia cells [nTPM]":"15.2","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.0","Single Cell Type RNA - Paneth cells [nTPM]":"9.1","Single Cell Type RNA - Peritubular cells [nTPM]":"9.1","Single Cell Type RNA - Plasma cells [nTPM]":"8.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"19.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"33.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.0","Single Cell Type RNA - Spermatocytes [nTPM]":"14.9","Single Cell Type RNA - Spermatogonia [nTPM]":"8.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.1","Single Cell Type RNA - T-cells [nTPM]":"6.9","Single Cell Type RNA - Theca cells [nTPM]":"19.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.3","Single Cell Type RNA - Urothelial cells [nTPM]":"3.1"},{"Gene":"TMIE","Gene synonym":["DFNB6"],"Ensembl":"ENSG00000181585","Gene description":"Transmembrane inner ear","Uniprot":["Q8NEW7"],"Chromosome":"3","Position":"46694528-46710886","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"19.6","choroid plexus":"10.5","pituitary gland":"9.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"3.8","Spermatocytes":"2.6","Spermatogonia":"3.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"6.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"2.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"15","RNA blood lineage specific nTPM":{"T-cells":"2.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"3.1","EFO-21":"2.7","JURKAT":"10.7","SH-SY5Y":"2.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038298"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA038298":"AB_10675792"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.7","Tissue RNA - adrenal gland [nTPM]":"6.2","Tissue RNA - amygdala [nTPM]":"14.2","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"14.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"14.0","Tissue RNA - cerebral cortex [nTPM]":"18.0","Tissue RNA - cervix [nTPM]":"0.7","Tissue RNA - choroid plexus [nTPM]":"10.5","Tissue RNA - colon [nTPM]":"1.0","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"0.5","Tissue RNA - epididymis [nTPM]":"0.7","Tissue RNA - esophagus [nTPM]":"1.5","Tissue RNA - fallopian tube [nTPM]":"0.6","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"0.7","Tissue RNA - hippocampal formation [nTPM]":"14.1","Tissue RNA - hypothalamus [nTPM]":"19.3","Tissue RNA - kidney [nTPM]":"2.3","Tissue RNA - liver [nTPM]":"0.8","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"0.8","Tissue RNA - medulla oblongata [nTPM]":"19.6","Tissue RNA - midbrain [nTPM]":"15.7","Tissue RNA - ovary [nTPM]":"1.5","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"9.9","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"19.2","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"0.7","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"3.6","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"16.0","Tissue RNA - spleen [nTPM]":"0.7","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"1.5","Tissue RNA - thalamus [nTPM]":"18.7","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"0.9","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"0.8","Tissue RNA - urinary bladder [nTPM]":"0.6","Tissue RNA - vagina [nTPM]":"0.9","Tissue RNA - white matter [nTPM]":"14.9","Cell RNA - A-431 [nTPM]":"1.0","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"3.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"2.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.8","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.8","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"1.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"1.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.5","Cell RNA - JURKAT [nTPM]":"10.7","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.7","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"1.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"2.3","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.7","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"2.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"14.2","Brain RNA - basal ganglia [nTPM]":"14.1","Brain RNA - cerebellum [nTPM]":"14.0","Brain RNA - cerebral cortex [nTPM]":"18.0","Brain RNA - hippocampal formation [nTPM]":"14.1","Brain RNA - hypothalamus [nTPM]":"19.3","Brain RNA - medulla oblongata [nTPM]":"19.6","Brain RNA - midbrain [nTPM]":"15.7","Brain RNA - pons [nTPM]":"19.2","Brain RNA - spinal cord [nTPM]":"16.0","Brain RNA - thalamus [nTPM]":"18.7","Brain RNA - white matter [nTPM]":"14.9","Single Cell Type RNA - Adipocytes [nTPM]":"1.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"3.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"1.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.0","Single Cell Type RNA - Spermatocytes [nTPM]":"2.6","Single Cell Type RNA - Spermatogonia [nTPM]":"3.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"TMLHE","Gene synonym":["BBOX2","FLJ10727","TMLH","XAP130"],"Ensembl":"ENSG00000185973","Gene description":"Trimethyllysine hydroxylase, epsilon","Uniprot":["Q9NVH6"],"Chromosome":"X","Position":"155489011-155719098","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carnitine biosynthesis"],"Molecular function":["Dioxygenase","Oxidoreductase"],"Disease involvement":["Autism","Autism spectrum disorder","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Microglial cells":"51.5","Oligodendrocyte precursor cells":"47.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034589","HPA040331"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA034589":"AB_10670571","HPA040331":"AB_2676929"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.68e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.7","Tissue RNA - adrenal gland [nTPM]":"10.2","Tissue RNA - amygdala [nTPM]":"7.1","Tissue RNA - appendix [nTPM]":"6.6","Tissue RNA - basal ganglia [nTPM]":"7.4","Tissue RNA - bone marrow [nTPM]":"8.4","Tissue RNA - breast [nTPM]":"11.3","Tissue RNA - cerebellum [nTPM]":"9.0","Tissue RNA - cerebral cortex [nTPM]":"8.0","Tissue RNA - cervix [nTPM]":"11.3","Tissue RNA - choroid plexus [nTPM]":"8.1","Tissue RNA - colon [nTPM]":"11.6","Tissue RNA - duodenum [nTPM]":"11.8","Tissue RNA - endometrium 1 [nTPM]":"9.4","Tissue RNA - epididymis [nTPM]":"10.4","Tissue RNA - esophagus [nTPM]":"10.3","Tissue RNA - fallopian tube [nTPM]":"9.9","Tissue RNA - gallbladder [nTPM]":"8.0","Tissue RNA - heart muscle [nTPM]":"25.3","Tissue RNA - hippocampal formation [nTPM]":"6.7","Tissue RNA - hypothalamus [nTPM]":"7.7","Tissue RNA - kidney [nTPM]":"16.7","Tissue RNA - liver [nTPM]":"18.8","Tissue RNA - lung [nTPM]":"5.6","Tissue RNA - lymph node [nTPM]":"7.0","Tissue RNA - medulla oblongata [nTPM]":"8.5","Tissue RNA - midbrain [nTPM]":"8.2","Tissue RNA - ovary [nTPM]":"12.0","Tissue RNA - pancreas [nTPM]":"9.5","Tissue RNA - parathyroid gland [nTPM]":"18.9","Tissue RNA - pituitary gland [nTPM]":"5.4","Tissue RNA - placenta [nTPM]":"8.4","Tissue RNA - pons [nTPM]":"8.5","Tissue RNA - prostate [nTPM]":"6.6","Tissue RNA - rectum [nTPM]":"12.5","Tissue RNA - retina [nTPM]":"10.9","Tissue RNA - salivary gland [nTPM]":"12.7","Tissue RNA - seminal vesicle [nTPM]":"9.7","Tissue RNA - skeletal muscle [nTPM]":"32.0","Tissue RNA - skin 1 [nTPM]":"5.9","Tissue RNA - small intestine [nTPM]":"11.2","Tissue RNA - smooth muscle [nTPM]":"12.3","Tissue RNA - spinal cord [nTPM]":"8.3","Tissue RNA - spleen [nTPM]":"8.7","Tissue RNA - stomach 1 [nTPM]":"9.1","Tissue RNA - testis [nTPM]":"2.9","Tissue RNA - thalamus [nTPM]":"7.3","Tissue RNA - thymus [nTPM]":"8.9","Tissue RNA - thyroid gland [nTPM]":"10.5","Tissue RNA - tongue [nTPM]":"33.4","Tissue RNA - tonsil [nTPM]":"7.6","Tissue RNA - urinary bladder [nTPM]":"8.2","Tissue RNA - vagina [nTPM]":"6.6","Tissue RNA - white matter [nTPM]":"9.8","Cell RNA - A-431 [nTPM]":"25.0","Cell RNA - A549 [nTPM]":"11.9","Cell RNA - AF22 [nTPM]":"9.8","Cell RNA - AN3-CA [nTPM]":"28.6","Cell RNA - ASC diff [nTPM]":"11.8","Cell RNA - ASC TERT1 [nTPM]":"18.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"9.9","Cell RNA - BJ hTERT+ [nTPM]":"14.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"32.4","Cell RNA - CACO-2 [nTPM]":"8.7","Cell RNA - CAPAN-2 [nTPM]":"13.9","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"38.9","Cell RNA - fHDF\/TERT166 [nTPM]":"17.6","Cell RNA - GAMG [nTPM]":"28.2","Cell RNA - HaCaT [nTPM]":"13.4","Cell RNA - HAP1 [nTPM]":"21.2","Cell RNA - HBEC3-KT [nTPM]":"9.7","Cell RNA - HBF TERT88 [nTPM]":"13.9","Cell RNA - HDLM-2 [nTPM]":"10.3","Cell RNA - HEK 293 [nTPM]":"14.3","Cell RNA - HEL [nTPM]":"11.3","Cell RNA - HeLa [nTPM]":"19.5","Cell RNA - Hep G2 [nTPM]":"10.2","Cell RNA - HHSteC [nTPM]":"16.4","Cell RNA - HL-60 [nTPM]":"10.5","Cell RNA - HMC-1 [nTPM]":"7.6","Cell RNA - HSkMC [nTPM]":"19.5","Cell RNA - hTCEpi [nTPM]":"20.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.6","Cell RNA - hTERT-HME1 [nTPM]":"20.8","Cell RNA - hTERT-RPE1 [nTPM]":"18.2","Cell RNA - HUVEC TERT2 [nTPM]":"19.5","Cell RNA - JURKAT [nTPM]":"15.5","Cell RNA - K-562 [nTPM]":"15.8","Cell RNA - Karpas-707 [nTPM]":"9.0","Cell RNA - LHCN-M2 [nTPM]":"20.5","Cell RNA - MCF7 [nTPM]":"9.3","Cell RNA - MOLT-4 [nTPM]":"12.8","Cell RNA - NB-4 [nTPM]":"11.8","Cell RNA - NTERA-2 [nTPM]":"3.0","Cell RNA - OE19 [nTPM]":"21.6","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"12.7","Cell RNA - RH-30 [nTPM]":"15.5","Cell RNA - RPMI-8226 [nTPM]":"9.4","Cell RNA - RPTEC TERT1 [nTPM]":"15.0","Cell RNA - RT4 [nTPM]":"8.5","Cell RNA - SCLC-21H [nTPM]":"9.2","Cell RNA - SH-SY5Y [nTPM]":"13.7","Cell RNA - SiHa [nTPM]":"9.3","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"11.2","Cell RNA - SuSa [nTPM]":"10.5","Cell RNA - T-47d [nTPM]":"10.6","Cell RNA - THP-1 [nTPM]":"11.9","Cell RNA - TIME [nTPM]":"16.5","Cell RNA - U-138 MG [nTPM]":"10.3","Cell RNA - U-2 OS [nTPM]":"9.7","Cell RNA - U-2197 [nTPM]":"20.4","Cell RNA - U-251 MG [nTPM]":"12.4","Cell RNA - U-266\/70 [nTPM]":"11.0","Cell RNA - U-266\/84 [nTPM]":"12.6","Cell RNA - U-698 [nTPM]":"9.6","Cell RNA - U-87 MG [nTPM]":"12.4","Cell RNA - U-937 [nTPM]":"16.4","Cell RNA - WM-115 [nTPM]":"9.6","Blood RNA - basophil [nTPM]":"3.4","Blood RNA - classical monocyte [nTPM]":"12.6","Blood RNA - eosinophil [nTPM]":"14.7","Blood RNA - gdT-cell [nTPM]":"4.6","Blood RNA - intermediate monocyte [nTPM]":"14.9","Blood RNA - MAIT T-cell [nTPM]":"3.5","Blood RNA - memory B-cell [nTPM]":"8.1","Blood RNA - memory CD4 T-cell [nTPM]":"5.0","Blood RNA - memory CD8 T-cell [nTPM]":"3.9","Blood RNA - myeloid DC [nTPM]":"13.1","Blood RNA - naive B-cell [nTPM]":"10.6","Blood RNA - naive CD4 T-cell [nTPM]":"6.5","Blood RNA - naive CD8 T-cell [nTPM]":"5.7","Blood RNA - neutrophil [nTPM]":"18.2","Blood RNA - NK-cell [nTPM]":"6.2","Blood RNA - non-classical monocyte [nTPM]":"21.5","Blood RNA - plasmacytoid DC [nTPM]":"6.1","Blood RNA - T-reg [nTPM]":"5.5","Blood RNA - total PBMC [nTPM]":"5.8","Brain RNA - amygdala [nTPM]":"7.1","Brain RNA - basal ganglia [nTPM]":"7.4","Brain RNA - cerebellum [nTPM]":"9.0","Brain RNA - cerebral cortex [nTPM]":"8.0","Brain RNA - hippocampal formation [nTPM]":"6.7","Brain RNA - hypothalamus [nTPM]":"7.7","Brain RNA - medulla oblongata [nTPM]":"8.5","Brain RNA - midbrain [nTPM]":"8.2","Brain RNA - pons [nTPM]":"8.5","Brain RNA - spinal cord [nTPM]":"8.3","Brain RNA - thalamus [nTPM]":"7.3","Brain RNA - white matter [nTPM]":"9.8","Single Cell Type RNA - Adipocytes [nTPM]":"6.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.3","Single Cell Type RNA - Astrocytes [nTPM]":"27.1","Single Cell Type RNA - B-cells [nTPM]":"10.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"4.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"9.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.8","Single Cell Type RNA - dendritic cells [nTPM]":"6.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"10.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.4","Single Cell Type RNA - Endothelial cells [nTPM]":"6.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.1","Single Cell Type RNA - Erythroid cells [nTPM]":"14.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.8","Single Cell Type RNA - Fibroblasts [nTPM]":"10.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.3","Single Cell Type RNA - granulocytes [nTPM]":"10.1","Single Cell Type RNA - Granulosa cells [nTPM]":"8.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.2","Single Cell Type RNA - Hepatocytes [nTPM]":"12.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"29.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.3","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"16.1","Single Cell Type RNA - Langerhans cells [nTPM]":"10.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"8.4","Single Cell Type RNA - Macrophages [nTPM]":"12.1","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"51.5","Single Cell Type RNA - monocytes [nTPM]":"13.1","Single Cell Type RNA - Muller glia cells [nTPM]":"7.6","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"47.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"25.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.5","Single Cell Type RNA - Paneth cells [nTPM]":"7.3","Single Cell Type RNA - Peritubular cells [nTPM]":"5.7","Single Cell Type RNA - Plasma cells [nTPM]":"5.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"2.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.7","Single Cell Type RNA - T-cells [nTPM]":"8.0","Single Cell Type RNA - Theca cells [nTPM]":"10.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.5","Single Cell Type RNA - Urothelial cells [nTPM]":"11.0"},{"Gene":"TMPRSS15","Gene synonym":["ENTK","MGC133046","PRSS7"],"Ensembl":"ENSG00000154646","Gene description":"Transmembrane serine protease 15","Uniprot":["P98073"],"Chromosome":"21","Position":"18269116-18485879","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"512","RNA tissue specific nTPM":{"intestine":"979.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Proximal enterocytes":"28.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"liver cancer":"0.7","pancreatic cancer":"1.5","stomach cancer":"1.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"19","RNA cell line specific nTPM":{"U-138 MG":"50.8","U-87 MG":"141.3"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"olfactory bulb":"5.0","spinal cord":"1.8"},"Antibody":["HPA015611","HPA034857","HPA072934"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA015611":"AB_1855791","HPA034857":null,"HPA072934":"AB_2732214"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.9","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.7","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"1.9","Tissue RNA - cerebral cortex [nTPM]":"1.7","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"979.8","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.7","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.6","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"21.8","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"1.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"1.8","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"4.8","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"3.9","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"4.9","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"4.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"50.8","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"141.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.9","Brain RNA - basal ganglia [nTPM]":"0.7","Brain RNA - cerebellum [nTPM]":"1.9","Brain RNA - cerebral cortex [nTPM]":"1.7","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.6","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"1.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"5.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"28.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"TMPRSS3","Gene synonym":["DFNB10","DFNB8"],"Ensembl":"ENSG00000160183","Gene description":"Transmembrane serine protease 3","Uniprot":["P57727"],"Chromosome":"21","Position":"42371887-42396091","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Cancer-related genes","Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"fallopian tube":"23.7","stomach 1":"14.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"17.7","Cholangiocytes":"24.3","Ductal cells":"16.1","Endometrial ciliated cells":"17.1","Gastric mucus-secreting cells":"23.4","Ionocytes":"16.2","Muller glia cells":"20.4","Respiratory ciliated cells":"39.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"16.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"3.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"T-cells":"3.1"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"U-266\/84":"274.7"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.47e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.64e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.24e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"3.8","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"4.0","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"8.7","Tissue RNA - cerebellum [nTPM]":"4.0","Tissue RNA - cerebral cortex [nTPM]":"3.7","Tissue RNA - cervix [nTPM]":"6.3","Tissue RNA - choroid plexus [nTPM]":"2.0","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"1.3","Tissue RNA - endometrium 1 [nTPM]":"0.7","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"23.7","Tissue RNA - gallbladder [nTPM]":"8.6","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"3.4","Tissue RNA - hypothalamus [nTPM]":"4.1","Tissue RNA - kidney [nTPM]":"2.4","Tissue RNA - liver [nTPM]":"0.5","Tissue RNA - lung [nTPM]":"3.4","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"4.9","Tissue RNA - midbrain [nTPM]":"4.7","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"3.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.5","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"3.7","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"3.9","Tissue RNA - salivary gland [nTPM]":"9.2","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"1.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"3.5","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"14.5","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"4.7","Tissue RNA - thymus [nTPM]":"0.9","Tissue RNA - thyroid gland [nTPM]":"2.9","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"1.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"2.7","Cell RNA - A-431 [nTPM]":"4.5","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"12.5","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"32.9","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"66.2","Cell RNA - HeLa [nTPM]":"26.5","Cell RNA - Hep G2 [nTPM]":"0.7","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"8.6","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"14.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.5","Cell RNA - MOLT-4 [nTPM]":"3.5","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"1.0","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"2.8","Cell RNA - RT4 [nTPM]":"1.5","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"33.9","Cell RNA - SK-BR-3 [nTPM]":"1.6","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"3.2","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.7","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"274.7","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"3.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"1.7","Blood RNA - memory CD8 T-cell [nTPM]":"1.8","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"3.8","Brain RNA - basal ganglia [nTPM]":"4.0","Brain RNA - cerebellum [nTPM]":"4.0","Brain RNA - cerebral cortex [nTPM]":"3.7","Brain RNA - hippocampal formation [nTPM]":"3.4","Brain RNA - hypothalamus [nTPM]":"4.1","Brain RNA - medulla oblongata [nTPM]":"4.9","Brain RNA - midbrain [nTPM]":"4.7","Brain RNA - pons [nTPM]":"3.7","Brain RNA - spinal cord [nTPM]":"3.5","Brain RNA - thalamus [nTPM]":"4.7","Brain RNA - white matter [nTPM]":"2.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.7","Single Cell Type RNA - Astrocytes [nTPM]":"2.3","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"10.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"16.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.0","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"20.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.8","Single Cell Type RNA - Paneth cells [nTPM]":"1.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"39.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.4","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.5","Single Cell Type RNA - Urothelial cells [nTPM]":"5.0"},{"Gene":"TMPRSS5","Gene synonym":["MGC141886","MGC148044"],"Ensembl":"ENSG00000166682","Gene description":"Transmembrane serine protease 5","Uniprot":["Q9H3S3"],"Chromosome":"11","Position":"113687547-113706373","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"50.6","choroid plexus":"20.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"26.4","Excitatory neurons":"5.4","Horizontal cells":"5.0","Oligodendrocytes":"15.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"5.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"2.0","CAPAN-2":"3.2","OE19":"2.0","WM-115":"2.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010992"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA010992":"AB_1858152"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-3"},"Tissue RNA - adipose tissue [nTPM]":"1.3","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"28.1","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"34.7","Tissue RNA - bone marrow [nTPM]":"1.4","Tissue RNA - breast [nTPM]":"2.0","Tissue RNA - cerebellum [nTPM]":"24.9","Tissue RNA - cerebral cortex [nTPM]":"39.0","Tissue RNA - cervix [nTPM]":"0.8","Tissue RNA - choroid plexus [nTPM]":"20.8","Tissue RNA - colon [nTPM]":"0.7","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.5","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.5","Tissue RNA - fallopian tube [nTPM]":"0.7","Tissue RNA - gallbladder [nTPM]":"0.7","Tissue RNA - heart muscle [nTPM]":"1.0","Tissue RNA - hippocampal formation [nTPM]":"28.2","Tissue RNA - hypothalamus [nTPM]":"27.0","Tissue RNA - kidney [nTPM]":"1.0","Tissue RNA - liver [nTPM]":"1.0","Tissue RNA - lung [nTPM]":"0.7","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"34.0","Tissue RNA - midbrain [nTPM]":"29.8","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"0.5","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.6","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"33.1","Tissue RNA - prostate [nTPM]":"0.8","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"1.1","Tissue RNA - salivary gland [nTPM]":"9.6","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"2.6","Tissue RNA - skin 1 [nTPM]":"2.1","Tissue RNA - small intestine [nTPM]":"0.7","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"28.5","Tissue RNA - spleen [nTPM]":"0.8","Tissue RNA - stomach 1 [nTPM]":"0.8","Tissue RNA - testis [nTPM]":"2.1","Tissue RNA - thalamus [nTPM]":"32.1","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"0.6","Tissue RNA - tongue [nTPM]":"0.5","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"0.7","Tissue RNA - vagina [nTPM]":"1.0","Tissue RNA - white matter [nTPM]":"50.6","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"2.0","Cell RNA - AN3-CA [nTPM]":"1.1","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.5","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"1.1","Cell RNA - CAPAN-2 [nTPM]":"3.2","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"1.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.5","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"2.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.3","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"0.4","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"1.6","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.4","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"2.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"28.1","Brain RNA - basal ganglia [nTPM]":"34.7","Brain RNA - cerebellum [nTPM]":"24.9","Brain RNA - cerebral cortex [nTPM]":"39.0","Brain RNA - hippocampal formation [nTPM]":"28.2","Brain RNA - hypothalamus [nTPM]":"27.0","Brain RNA - medulla oblongata [nTPM]":"34.0","Brain RNA - midbrain [nTPM]":"29.8","Brain RNA - pons [nTPM]":"33.1","Brain RNA - spinal cord [nTPM]":"28.5","Brain RNA - thalamus [nTPM]":"32.1","Brain RNA - white matter [nTPM]":"50.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"26.4","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"3.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"TMPRSS6","Gene synonym":["FLJ30744","MT2"],"Ensembl":"ENSG00000187045","Gene description":"Transmembrane serine protease 6","Uniprot":["Q8IU80"],"Chromosome":"22","Position":"37065436-37109713","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"liver":"128.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Early spermatids":"61.0","Hepatocytes":"99.9","Late spermatids":"143.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"14","RNA cancer specific FPKM":{"liver cancer":"51.3","thyroid cancer":"14.1"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"basal ganglia":"4.4","thalamus":"1.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Hep G2":"5.0","SCLC-21H":"8.1"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"basal ganglia":"3.3"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.16e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-5"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"4.4","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.6","Tissue RNA - duodenum [nTPM]":"2.2","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.8","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"0.9","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"128.4","Tissue RNA - lung [nTPM]":"0.7","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"1.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"13.0","Tissue RNA - placenta [nTPM]":"0.7","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"2.2","Tissue RNA - small intestine [nTPM]":"1.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"3.6","Tissue RNA - testis [nTPM]":"7.7","Tissue RNA - thalamus [nTPM]":"1.3","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.6","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"1.3","Cell RNA - HEK 293 [nTPM]":"1.5","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"5.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.9","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"8.1","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"1.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"1.0","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"4.4","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"1.3","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"61.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.3","Single Cell Type RNA - Erythroid cells [nTPM]":"8.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.6","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"99.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.2","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"143.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"1.6","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"TMTC3","Gene synonym":["FLJ90492","SMILE"],"Ensembl":"ENSG00000139324","Gene description":"Transmembrane O-mannosyltransferase targeting cadherins 3","Uniprot":["Q6ZXV5"],"Chromosome":"12","Position":"88142296-88199887","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Lissencephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ionocytes":"75.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038550"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 61: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038550":"AB_10672715"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.9","Tissue RNA - adrenal gland [nTPM]":"4.4","Tissue RNA - amygdala [nTPM]":"3.6","Tissue RNA - appendix [nTPM]":"3.8","Tissue RNA - basal ganglia [nTPM]":"3.8","Tissue RNA - bone marrow [nTPM]":"1.7","Tissue RNA - breast [nTPM]":"6.7","Tissue RNA - cerebellum [nTPM]":"5.8","Tissue RNA - cerebral cortex [nTPM]":"4.7","Tissue RNA - cervix [nTPM]":"5.6","Tissue RNA - choroid plexus [nTPM]":"2.1","Tissue RNA - colon [nTPM]":"4.5","Tissue RNA - duodenum [nTPM]":"5.4","Tissue RNA - endometrium 1 [nTPM]":"6.4","Tissue RNA - epididymis [nTPM]":"5.2","Tissue RNA - esophagus [nTPM]":"9.1","Tissue RNA - fallopian tube [nTPM]":"3.9","Tissue RNA - gallbladder [nTPM]":"5.7","Tissue RNA - heart muscle [nTPM]":"3.8","Tissue RNA - hippocampal formation [nTPM]":"3.9","Tissue RNA - hypothalamus [nTPM]":"4.6","Tissue RNA - kidney [nTPM]":"8.1","Tissue RNA - liver [nTPM]":"9.0","Tissue RNA - lung [nTPM]":"5.2","Tissue RNA - lymph node [nTPM]":"2.9","Tissue RNA - medulla oblongata [nTPM]":"3.4","Tissue RNA - midbrain [nTPM]":"3.9","Tissue RNA - ovary [nTPM]":"5.3","Tissue RNA - pancreas [nTPM]":"3.2","Tissue RNA - parathyroid gland [nTPM]":"6.2","Tissue RNA - pituitary gland [nTPM]":"2.8","Tissue RNA - placenta [nTPM]":"10.2","Tissue RNA - pons [nTPM]":"4.1","Tissue RNA - prostate [nTPM]":"7.4","Tissue RNA - rectum [nTPM]":"4.7","Tissue RNA - retina [nTPM]":"7.9","Tissue RNA - salivary gland [nTPM]":"3.8","Tissue RNA - seminal vesicle [nTPM]":"6.3","Tissue RNA - skeletal muscle [nTPM]":"1.7","Tissue RNA - skin 1 [nTPM]":"12.5","Tissue RNA - small intestine [nTPM]":"4.4","Tissue RNA - smooth muscle [nTPM]":"9.2","Tissue RNA - spinal cord [nTPM]":"3.2","Tissue RNA - spleen [nTPM]":"3.9","Tissue RNA - stomach 1 [nTPM]":"3.8","Tissue RNA - testis [nTPM]":"4.1","Tissue RNA - thalamus [nTPM]":"3.6","Tissue RNA - thymus [nTPM]":"4.0","Tissue RNA - thyroid gland [nTPM]":"6.3","Tissue RNA - tongue [nTPM]":"4.3","Tissue RNA - tonsil [nTPM]":"4.5","Tissue RNA - urinary bladder [nTPM]":"6.8","Tissue RNA - vagina [nTPM]":"4.7","Tissue RNA - white matter [nTPM]":"4.1","Cell RNA - A-431 [nTPM]":"13.2","Cell RNA - A549 [nTPM]":"14.0","Cell RNA - AF22 [nTPM]":"12.6","Cell RNA - AN3-CA [nTPM]":"11.9","Cell RNA - ASC diff [nTPM]":"28.8","Cell RNA - ASC TERT1 [nTPM]":"25.4","Cell RNA - BEWO [nTPM]":"22.5","Cell RNA - BJ [nTPM]":"28.1","Cell RNA - BJ hTERT+ [nTPM]":"26.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.9","Cell RNA - CACO-2 [nTPM]":"20.3","Cell RNA - CAPAN-2 [nTPM]":"9.2","Cell RNA - Daudi [nTPM]":"4.1","Cell RNA - EFO-21 [nTPM]":"5.0","Cell RNA - fHDF\/TERT166 [nTPM]":"25.8","Cell RNA - GAMG [nTPM]":"9.6","Cell RNA - HaCaT [nTPM]":"28.9","Cell RNA - HAP1 [nTPM]":"13.5","Cell RNA - HBEC3-KT [nTPM]":"22.4","Cell RNA - HBF TERT88 [nTPM]":"26.5","Cell RNA - HDLM-2 [nTPM]":"2.4","Cell RNA - HEK 293 [nTPM]":"10.2","Cell RNA - HEL [nTPM]":"4.0","Cell RNA - HeLa [nTPM]":"9.5","Cell RNA - Hep G2 [nTPM]":"9.3","Cell RNA - HHSteC [nTPM]":"15.0","Cell RNA - HL-60 [nTPM]":"4.3","Cell RNA - HMC-1 [nTPM]":"2.5","Cell RNA - HSkMC [nTPM]":"21.7","Cell RNA - hTCEpi [nTPM]":"12.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"30.5","Cell RNA - hTERT-HME1 [nTPM]":"12.0","Cell RNA - hTERT-RPE1 [nTPM]":"16.2","Cell RNA - HUVEC TERT2 [nTPM]":"24.9","Cell RNA - JURKAT [nTPM]":"3.4","Cell RNA - K-562 [nTPM]":"8.9","Cell RNA - Karpas-707 [nTPM]":"1.4","Cell RNA - LHCN-M2 [nTPM]":"17.8","Cell RNA - MCF7 [nTPM]":"7.9","Cell RNA - MOLT-4 [nTPM]":"3.0","Cell RNA - NB-4 [nTPM]":"5.5","Cell RNA - NTERA-2 [nTPM]":"9.7","Cell RNA - OE19 [nTPM]":"5.0","Cell RNA - PC-3 [nTPM]":"7.3","Cell RNA - REH [nTPM]":"2.6","Cell RNA - RH-30 [nTPM]":"27.4","Cell RNA - RPMI-8226 [nTPM]":"4.1","Cell RNA - RPTEC TERT1 [nTPM]":"13.7","Cell RNA - RT4 [nTPM]":"21.3","Cell RNA - SCLC-21H [nTPM]":"10.7","Cell RNA - SH-SY5Y [nTPM]":"10.6","Cell RNA - SiHa [nTPM]":"22.8","Cell RNA - SK-BR-3 [nTPM]":"16.1","Cell RNA - SK-MEL-30 [nTPM]":"7.3","Cell RNA - SuSa [nTPM]":"13.3","Cell RNA - T-47d [nTPM]":"25.9","Cell RNA - THP-1 [nTPM]":"4.3","Cell RNA - TIME [nTPM]":"26.4","Cell RNA - U-138 MG [nTPM]":"21.8","Cell RNA - U-2 OS [nTPM]":"12.0","Cell RNA - U-2197 [nTPM]":"19.4","Cell RNA - U-251 MG [nTPM]":"13.7","Cell RNA - U-266\/70 [nTPM]":"4.5","Cell RNA - U-266\/84 [nTPM]":"6.3","Cell RNA - U-698 [nTPM]":"4.7","Cell RNA - U-87 MG [nTPM]":"6.8","Cell RNA - U-937 [nTPM]":"5.0","Cell RNA - WM-115 [nTPM]":"16.5","Blood RNA - basophil [nTPM]":"7.4","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"2.3","Blood RNA - gdT-cell [nTPM]":"1.8","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"2.2","Blood RNA - memory B-cell [nTPM]":"2.3","Blood RNA - memory CD4 T-cell [nTPM]":"2.0","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"0.9","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"2.4","Blood RNA - naive CD8 T-cell [nTPM]":"2.0","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"1.2","Blood RNA - non-classical monocyte [nTPM]":"1.6","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"1.7","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"3.6","Brain RNA - basal ganglia [nTPM]":"3.8","Brain RNA - cerebellum [nTPM]":"5.8","Brain RNA - cerebral cortex [nTPM]":"4.7","Brain RNA - hippocampal formation [nTPM]":"3.9","Brain RNA - hypothalamus [nTPM]":"4.6","Brain RNA - medulla oblongata [nTPM]":"3.4","Brain RNA - midbrain [nTPM]":"3.9","Brain RNA - pons [nTPM]":"4.1","Brain RNA - spinal cord [nTPM]":"3.2","Brain RNA - thalamus [nTPM]":"3.6","Brain RNA - white matter [nTPM]":"4.1","Single Cell Type RNA - Adipocytes [nTPM]":"15.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.2","Single Cell Type RNA - Astrocytes [nTPM]":"19.6","Single Cell Type RNA - B-cells [nTPM]":"6.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"34.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"12.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"20.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"29.6","Single Cell Type RNA - dendritic cells [nTPM]":"3.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"14.5","Single Cell Type RNA - Early spermatids [nTPM]":"26.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.2","Single Cell Type RNA - Endothelial cells [nTPM]":"16.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"9.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"51.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.2","Single Cell Type RNA - Fibroblasts [nTPM]":"23.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.9","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"12.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.7","Single Cell Type RNA - Hepatocytes [nTPM]":"19.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.2","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"46.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.9","Single Cell Type RNA - Ionocytes [nTPM]":"75.3","Single Cell Type RNA - Kupffer cells [nTPM]":"5.9","Single Cell Type RNA - Langerhans cells [nTPM]":"6.0","Single Cell Type RNA - Late spermatids [nTPM]":"18.2","Single Cell Type RNA - Leydig cells [nTPM]":"20.2","Single Cell Type RNA - Macrophages [nTPM]":"3.7","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"2.8","Single Cell Type RNA - Muller glia cells [nTPM]":"8.3","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"28.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"42.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.4","Single Cell Type RNA - Paneth cells [nTPM]":"4.9","Single Cell Type RNA - Peritubular cells [nTPM]":"19.5","Single Cell Type RNA - Plasma cells [nTPM]":"4.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"34.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.4","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.3","Single Cell Type RNA - Spermatocytes [nTPM]":"12.0","Single Cell Type RNA - Spermatogonia [nTPM]":"8.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"32.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"40.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.8","Single Cell Type RNA - T-cells [nTPM]":"5.2","Single Cell Type RNA - Theca cells [nTPM]":"14.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.1","Single Cell Type RNA - Urothelial cells [nTPM]":"14.4"},{"Gene":"TMX2","Gene synonym":["PDIA12","TXNDC14"],"Ensembl":"ENSG00000213593","Gene description":"Thioredoxin related transmembrane protein 2","Uniprot":["Q9Y320"],"Chromosome":"11","Position":"57712593-57740973","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Lissencephaly","Mental retardation","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040282","HPA063763"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA040282":"AB_10697715","HPA063763":"AB_2685116"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.64e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.11e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.55e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.37e-4"},"Tissue RNA - adipose tissue [nTPM]":"52.9","Tissue RNA - adrenal gland [nTPM]":"75.1","Tissue RNA - amygdala [nTPM]":"77.7","Tissue RNA - appendix [nTPM]":"37.3","Tissue RNA - basal ganglia [nTPM]":"83.0","Tissue RNA - bone marrow [nTPM]":"27.0","Tissue RNA - breast [nTPM]":"50.5","Tissue RNA - cerebellum [nTPM]":"87.4","Tissue RNA - cerebral cortex [nTPM]":"101.9","Tissue RNA - cervix [nTPM]":"43.6","Tissue RNA - choroid plexus [nTPM]":"103.3","Tissue RNA - colon [nTPM]":"70.0","Tissue RNA - duodenum [nTPM]":"56.4","Tissue RNA - endometrium 1 [nTPM]":"39.4","Tissue RNA - epididymis [nTPM]":"58.2","Tissue RNA - esophagus [nTPM]":"62.8","Tissue RNA - fallopian tube [nTPM]":"42.7","Tissue RNA - gallbladder [nTPM]":"33.2","Tissue RNA - heart muscle [nTPM]":"71.5","Tissue RNA - hippocampal formation [nTPM]":"75.0","Tissue RNA - hypothalamus [nTPM]":"84.1","Tissue RNA - kidney [nTPM]":"78.7","Tissue RNA - liver [nTPM]":"83.4","Tissue RNA - lung [nTPM]":"45.0","Tissue RNA - lymph node [nTPM]":"31.5","Tissue RNA - medulla oblongata [nTPM]":"81.7","Tissue RNA - midbrain [nTPM]":"81.5","Tissue RNA - ovary [nTPM]":"40.9","Tissue RNA - pancreas [nTPM]":"57.7","Tissue RNA - parathyroid gland [nTPM]":"84.9","Tissue RNA - pituitary gland [nTPM]":"43.1","Tissue RNA - placenta [nTPM]":"44.0","Tissue RNA - pons [nTPM]":"83.5","Tissue RNA - prostate [nTPM]":"50.1","Tissue RNA - rectum [nTPM]":"80.8","Tissue RNA - retina [nTPM]":"64.7","Tissue RNA - salivary gland [nTPM]":"49.6","Tissue RNA - seminal vesicle [nTPM]":"53.8","Tissue RNA - skeletal muscle [nTPM]":"44.7","Tissue RNA - skin 1 [nTPM]":"45.1","Tissue RNA - small intestine [nTPM]":"58.3","Tissue RNA - smooth muscle [nTPM]":"43.1","Tissue RNA - spinal cord [nTPM]":"84.3","Tissue RNA - spleen [nTPM]":"44.9","Tissue RNA - stomach 1 [nTPM]":"60.9","Tissue RNA - testis [nTPM]":"30.6","Tissue RNA - thalamus [nTPM]":"85.5","Tissue RNA - thymus [nTPM]":"34.9","Tissue RNA - thyroid gland [nTPM]":"57.1","Tissue RNA - tongue [nTPM]":"41.3","Tissue RNA - tonsil [nTPM]":"47.6","Tissue RNA - urinary bladder [nTPM]":"48.2","Tissue RNA - vagina [nTPM]":"43.8","Tissue RNA - white matter [nTPM]":"90.6","Cell RNA - A-431 [nTPM]":"122.7","Cell RNA - A549 [nTPM]":"141.4","Cell RNA - AF22 [nTPM]":"78.5","Cell RNA - AN3-CA [nTPM]":"143.4","Cell RNA - ASC diff [nTPM]":"144.8","Cell RNA - ASC TERT1 [nTPM]":"77.2","Cell RNA - BEWO [nTPM]":"86.6","Cell RNA - BJ [nTPM]":"144.2","Cell RNA - BJ hTERT+ [nTPM]":"111.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"140.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"117.9","Cell RNA - CACO-2 [nTPM]":"135.3","Cell RNA - CAPAN-2 [nTPM]":"205.6","Cell RNA - Daudi [nTPM]":"115.1","Cell RNA - EFO-21 [nTPM]":"156.6","Cell RNA - fHDF\/TERT166 [nTPM]":"116.3","Cell RNA - GAMG [nTPM]":"207.1","Cell RNA - HaCaT [nTPM]":"220.0","Cell RNA - HAP1 [nTPM]":"203.5","Cell RNA - HBEC3-KT [nTPM]":"115.4","Cell RNA - HBF TERT88 [nTPM]":"146.3","Cell RNA - HDLM-2 [nTPM]":"83.3","Cell RNA - HEK 293 [nTPM]":"88.9","Cell RNA - HEL [nTPM]":"110.2","Cell RNA - HeLa [nTPM]":"105.7","Cell RNA - Hep G2 [nTPM]":"136.8","Cell RNA - HHSteC [nTPM]":"119.3","Cell RNA - HL-60 [nTPM]":"156.6","Cell RNA - HMC-1 [nTPM]":"145.5","Cell RNA - HSkMC [nTPM]":"94.8","Cell RNA - hTCEpi [nTPM]":"166.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"154.8","Cell RNA - hTERT-HME1 [nTPM]":"243.2","Cell RNA - hTERT-RPE1 [nTPM]":"76.3","Cell RNA - HUVEC TERT2 [nTPM]":"80.6","Cell RNA - JURKAT [nTPM]":"95.3","Cell RNA - K-562 [nTPM]":"194.4","Cell RNA - Karpas-707 [nTPM]":"130.9","Cell RNA - LHCN-M2 [nTPM]":"157.7","Cell RNA - MCF7 [nTPM]":"62.7","Cell RNA - MOLT-4 [nTPM]":"93.0","Cell RNA - NB-4 [nTPM]":"177.1","Cell RNA - NTERA-2 [nTPM]":"153.8","Cell RNA - OE19 [nTPM]":"227.7","Cell RNA - PC-3 [nTPM]":"191.5","Cell RNA - REH [nTPM]":"124.7","Cell RNA - RH-30 [nTPM]":"97.9","Cell RNA - RPMI-8226 [nTPM]":"242.5","Cell RNA - RPTEC TERT1 [nTPM]":"174.4","Cell RNA - RT4 [nTPM]":"136.4","Cell RNA - SCLC-21H [nTPM]":"90.3","Cell RNA - SH-SY5Y [nTPM]":"129.3","Cell RNA - SiHa [nTPM]":"110.2","Cell RNA - SK-BR-3 [nTPM]":"255.7","Cell RNA - SK-MEL-30 [nTPM]":"168.3","Cell RNA - SuSa [nTPM]":"76.7","Cell RNA - T-47d [nTPM]":"228.5","Cell RNA - THP-1 [nTPM]":"102.2","Cell RNA - TIME [nTPM]":"66.7","Cell RNA - U-138 MG [nTPM]":"130.5","Cell RNA - U-2 OS [nTPM]":"84.8","Cell RNA - U-2197 [nTPM]":"176.1","Cell RNA - U-251 MG [nTPM]":"152.1","Cell RNA - U-266\/70 [nTPM]":"127.9","Cell RNA - U-266\/84 [nTPM]":"269.5","Cell RNA - U-698 [nTPM]":"115.3","Cell RNA - U-87 MG [nTPM]":"146.6","Cell RNA - U-937 [nTPM]":"109.3","Cell RNA - WM-115 [nTPM]":"198.3","Blood RNA - basophil [nTPM]":"37.8","Blood RNA - classical monocyte [nTPM]":"41.5","Blood RNA - eosinophil [nTPM]":"40.0","Blood RNA - gdT-cell [nTPM]":"34.6","Blood RNA - intermediate monocyte [nTPM]":"72.4","Blood RNA - MAIT T-cell [nTPM]":"44.0","Blood RNA - memory B-cell [nTPM]":"36.8","Blood RNA - memory CD4 T-cell [nTPM]":"34.4","Blood RNA - memory CD8 T-cell [nTPM]":"40.9","Blood RNA - myeloid DC [nTPM]":"40.6","Blood RNA - naive B-cell [nTPM]":"34.9","Blood RNA - naive CD4 T-cell [nTPM]":"43.1","Blood RNA - naive CD8 T-cell [nTPM]":"43.8","Blood RNA - neutrophil [nTPM]":"11.2","Blood RNA - NK-cell [nTPM]":"37.8","Blood RNA - non-classical monocyte [nTPM]":"86.0","Blood RNA - plasmacytoid DC [nTPM]":"49.7","Blood RNA - T-reg [nTPM]":"32.0","Blood RNA - total PBMC [nTPM]":"45.0","Brain RNA - amygdala [nTPM]":"77.7","Brain RNA - basal ganglia [nTPM]":"83.0","Brain RNA - cerebellum [nTPM]":"87.4","Brain RNA - cerebral cortex [nTPM]":"101.9","Brain RNA - hippocampal formation [nTPM]":"75.0","Brain RNA - hypothalamus [nTPM]":"84.1","Brain RNA - medulla oblongata [nTPM]":"81.7","Brain RNA - midbrain [nTPM]":"81.5","Brain RNA - pons [nTPM]":"83.5","Brain RNA - spinal cord [nTPM]":"84.3","Brain RNA - thalamus [nTPM]":"85.5","Brain RNA - white matter [nTPM]":"90.6","Single Cell Type RNA - Adipocytes [nTPM]":"37.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"34.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"32.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"32.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"44.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"108.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.9","Single Cell Type RNA - Bipolar cells [nTPM]":"43.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"35.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"28.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"42.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"60.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"49.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"108.0","Single Cell Type RNA - dendritic cells [nTPM]":"29.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"39.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"43.0","Single Cell Type RNA - Ductal cells [nTPM]":"72.4","Single Cell Type RNA - Early spermatids [nTPM]":"2.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"27.4","Single Cell Type RNA - Endothelial cells [nTPM]":"36.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"28.8","Single Cell Type RNA - Erythroid cells [nTPM]":"37.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"43.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"85.6","Single Cell Type RNA - Fibroblasts [nTPM]":"38.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.7","Single Cell Type RNA - granulocytes [nTPM]":"43.1","Single Cell Type RNA - Granulosa cells [nTPM]":"29.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"31.8","Single Cell Type RNA - Hepatocytes [nTPM]":"48.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"62.0","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"49.6","Single Cell Type RNA - Ionocytes [nTPM]":"81.4","Single Cell Type RNA - Kupffer cells [nTPM]":"30.8","Single Cell Type RNA - Langerhans cells [nTPM]":"21.4","Single Cell Type RNA - Late spermatids [nTPM]":"3.6","Single Cell Type RNA - Leydig cells [nTPM]":"48.7","Single Cell Type RNA - Macrophages [nTPM]":"31.9","Single Cell Type RNA - Melanocytes [nTPM]":"48.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"37.8","Single Cell Type RNA - Muller glia cells [nTPM]":"91.1","Single Cell Type RNA - NK-cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"54.5","Single Cell Type RNA - Paneth cells [nTPM]":"32.0","Single Cell Type RNA - Peritubular cells [nTPM]":"43.6","Single Cell Type RNA - Plasma cells [nTPM]":"32.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"49.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"51.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"41.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"37.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"66.7","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"36.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"34.5","Single Cell Type RNA - Spermatocytes [nTPM]":"60.7","Single Cell Type RNA - Spermatogonia [nTPM]":"62.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"33.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"32.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"99.6","Single Cell Type RNA - T-cells [nTPM]":"26.6","Single Cell Type RNA - Theca cells [nTPM]":"46.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"75.2","Single Cell Type RNA - Urothelial cells [nTPM]":"43.6"},{"Gene":"TNFAIP3","Gene synonym":["A20","OTUD7C"],"Ensembl":"ENSG00000118503","Gene description":"TNF alpha induced protein 3","Uniprot":["P21580"],"Chromosome":"6","Position":"137867214-137883312","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Inflammatory response","Ubl conjugation pathway"],"Molecular function":["DNA-binding","Hydrolase","Multifunctional enzyme","Protease","Thiol protease","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"519.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"774.9","Endometrial ciliated cells":"605.2","Glandular and luminal cells":"1498.3","Macrophages":"596.6","Suprabasal keratinocytes":"745.7","T-cells":"624.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"GAMG":"106.5","Karpas-707":"161.3","REH":"151.5","U-266\/84":"131.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002116"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Centrosome","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA002116":"AB_1858162"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.05e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"},"Tissue RNA - adipose tissue [nTPM]":"57.0","Tissue RNA - adrenal gland [nTPM]":"15.6","Tissue RNA - amygdala [nTPM]":"4.4","Tissue RNA - appendix [nTPM]":"114.6","Tissue RNA - basal ganglia [nTPM]":"3.8","Tissue RNA - bone marrow [nTPM]":"519.5","Tissue RNA - breast [nTPM]":"23.3","Tissue RNA - cerebellum [nTPM]":"2.9","Tissue RNA - cerebral cortex [nTPM]":"23.9","Tissue RNA - cervix [nTPM]":"27.5","Tissue RNA - choroid plexus [nTPM]":"12.0","Tissue RNA - colon [nTPM]":"22.6","Tissue RNA - duodenum [nTPM]":"21.4","Tissue RNA - endometrium 1 [nTPM]":"31.3","Tissue RNA - epididymis [nTPM]":"5.2","Tissue RNA - esophagus [nTPM]":"26.6","Tissue RNA - fallopian tube [nTPM]":"23.4","Tissue RNA - gallbladder [nTPM]":"47.8","Tissue RNA - heart muscle [nTPM]":"23.0","Tissue RNA - hippocampal formation [nTPM]":"3.2","Tissue RNA - hypothalamus [nTPM]":"2.8","Tissue RNA - kidney [nTPM]":"13.8","Tissue RNA - liver [nTPM]":"27.4","Tissue RNA - lung [nTPM]":"56.2","Tissue RNA - lymph node [nTPM]":"76.8","Tissue RNA - medulla oblongata [nTPM]":"6.1","Tissue RNA - midbrain [nTPM]":"3.9","Tissue RNA - ovary [nTPM]":"73.2","Tissue RNA - pancreas [nTPM]":"25.8","Tissue RNA - parathyroid gland [nTPM]":"25.8","Tissue RNA - pituitary gland [nTPM]":"7.5","Tissue RNA - placenta [nTPM]":"28.9","Tissue RNA - pons [nTPM]":"6.7","Tissue RNA - prostate [nTPM]":"17.3","Tissue RNA - rectum [nTPM]":"24.7","Tissue RNA - retina [nTPM]":"19.1","Tissue RNA - salivary gland [nTPM]":"16.1","Tissue RNA - seminal vesicle [nTPM]":"10.3","Tissue RNA - skeletal muscle [nTPM]":"8.6","Tissue RNA - skin 1 [nTPM]":"50.5","Tissue RNA - small intestine [nTPM]":"30.7","Tissue RNA - smooth muscle [nTPM]":"33.5","Tissue RNA - spinal cord [nTPM]":"6.6","Tissue RNA - spleen [nTPM]":"46.1","Tissue RNA - stomach 1 [nTPM]":"22.8","Tissue RNA - testis [nTPM]":"8.3","Tissue RNA - thalamus [nTPM]":"9.5","Tissue RNA - thymus [nTPM]":"71.1","Tissue RNA - thyroid gland [nTPM]":"11.7","Tissue RNA - tongue [nTPM]":"3.8","Tissue RNA - tonsil [nTPM]":"55.7","Tissue RNA - urinary bladder [nTPM]":"171.1","Tissue RNA - vagina [nTPM]":"14.6","Tissue RNA - white matter [nTPM]":"6.2","Cell RNA - A-431 [nTPM]":"32.6","Cell RNA - A549 [nTPM]":"4.8","Cell RNA - AF22 [nTPM]":"1.8","Cell RNA - AN3-CA [nTPM]":"2.8","Cell RNA - ASC diff [nTPM]":"10.1","Cell RNA - ASC TERT1 [nTPM]":"16.9","Cell RNA - BEWO [nTPM]":"7.8","Cell RNA - BJ [nTPM]":"18.8","Cell RNA - BJ hTERT+ [nTPM]":"67.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.7","Cell RNA - CACO-2 [nTPM]":"34.9","Cell RNA - CAPAN-2 [nTPM]":"8.8","Cell RNA - Daudi [nTPM]":"7.3","Cell RNA - EFO-21 [nTPM]":"43.1","Cell RNA - fHDF\/TERT166 [nTPM]":"20.0","Cell RNA - GAMG [nTPM]":"106.5","Cell RNA - HaCaT [nTPM]":"22.6","Cell RNA - HAP1 [nTPM]":"1.1","Cell RNA - HBEC3-KT [nTPM]":"50.4","Cell RNA - HBF TERT88 [nTPM]":"8.9","Cell RNA - HDLM-2 [nTPM]":"46.8","Cell RNA - HEK 293 [nTPM]":"2.2","Cell RNA - HEL [nTPM]":"7.5","Cell RNA - HeLa [nTPM]":"19.8","Cell RNA - Hep G2 [nTPM]":"21.1","Cell RNA - HHSteC [nTPM]":"11.2","Cell RNA - HL-60 [nTPM]":"10.3","Cell RNA - HMC-1 [nTPM]":"12.8","Cell RNA - HSkMC [nTPM]":"15.6","Cell RNA - hTCEpi [nTPM]":"7.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"56.4","Cell RNA - hTERT-HME1 [nTPM]":"53.6","Cell RNA - hTERT-RPE1 [nTPM]":"5.6","Cell RNA - HUVEC TERT2 [nTPM]":"2.9","Cell RNA - JURKAT [nTPM]":"21.2","Cell RNA - K-562 [nTPM]":"17.4","Cell RNA - Karpas-707 [nTPM]":"161.3","Cell RNA - LHCN-M2 [nTPM]":"8.4","Cell RNA - MCF7 [nTPM]":"1.8","Cell RNA - MOLT-4 [nTPM]":"56.2","Cell RNA - NB-4 [nTPM]":"41.4","Cell RNA - NTERA-2 [nTPM]":"1.5","Cell RNA - OE19 [nTPM]":"2.1","Cell RNA - PC-3 [nTPM]":"1.4","Cell RNA - REH [nTPM]":"151.5","Cell RNA - RH-30 [nTPM]":"39.4","Cell RNA - RPMI-8226 [nTPM]":"6.1","Cell RNA - RPTEC TERT1 [nTPM]":"14.8","Cell RNA - RT4 [nTPM]":"15.1","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"3.6","Cell RNA - SK-BR-3 [nTPM]":"5.3","Cell RNA - SK-MEL-30 [nTPM]":"16.9","Cell RNA - SuSa [nTPM]":"7.0","Cell RNA - T-47d [nTPM]":"3.4","Cell RNA - THP-1 [nTPM]":"11.7","Cell RNA - TIME [nTPM]":"14.8","Cell RNA - U-138 MG [nTPM]":"46.9","Cell RNA - U-2 OS [nTPM]":"6.8","Cell RNA - U-2197 [nTPM]":"46.0","Cell RNA - U-251 MG [nTPM]":"9.6","Cell RNA - U-266\/70 [nTPM]":"48.7","Cell RNA - U-266\/84 [nTPM]":"131.4","Cell RNA - U-698 [nTPM]":"14.0","Cell RNA - U-87 MG [nTPM]":"16.9","Cell RNA - U-937 [nTPM]":"13.1","Cell RNA - WM-115 [nTPM]":"6.1","Blood RNA - basophil [nTPM]":"7.3","Blood RNA - classical monocyte [nTPM]":"12.6","Blood RNA - eosinophil [nTPM]":"9.6","Blood RNA - gdT-cell [nTPM]":"19.6","Blood RNA - intermediate monocyte [nTPM]":"9.3","Blood RNA - MAIT T-cell [nTPM]":"27.9","Blood RNA - memory B-cell [nTPM]":"7.4","Blood RNA - memory CD4 T-cell [nTPM]":"19.4","Blood RNA - memory CD8 T-cell [nTPM]":"18.0","Blood RNA - myeloid DC [nTPM]":"14.3","Blood RNA - naive B-cell [nTPM]":"7.8","Blood RNA - naive CD4 T-cell [nTPM]":"13.1","Blood RNA - naive CD8 T-cell [nTPM]":"10.1","Blood RNA - neutrophil [nTPM]":"13.6","Blood RNA - NK-cell [nTPM]":"11.1","Blood RNA - non-classical monocyte [nTPM]":"5.1","Blood RNA - plasmacytoid DC [nTPM]":"26.2","Blood RNA - T-reg [nTPM]":"19.2","Blood RNA - total PBMC [nTPM]":"14.8","Brain RNA - amygdala [nTPM]":"4.4","Brain RNA - basal ganglia [nTPM]":"3.8","Brain RNA - cerebellum [nTPM]":"2.9","Brain RNA - cerebral cortex [nTPM]":"23.9","Brain RNA - hippocampal formation [nTPM]":"3.2","Brain RNA - hypothalamus [nTPM]":"2.8","Brain RNA - medulla oblongata [nTPM]":"6.1","Brain RNA - midbrain [nTPM]":"3.9","Brain RNA - pons [nTPM]":"6.7","Brain RNA - spinal cord [nTPM]":"6.6","Brain RNA - thalamus [nTPM]":"9.5","Brain RNA - white matter [nTPM]":"6.2","Single Cell Type RNA - Adipocytes [nTPM]":"71.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"76.3","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"94.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"774.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"150.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"102.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"384.7","Single Cell Type RNA - Bipolar cells [nTPM]":"1.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"42.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"53.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.1","Single Cell Type RNA - dendritic cells [nTPM]":"395.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"53.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"60.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"605.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"365.9","Single Cell Type RNA - Endothelial cells [nTPM]":"114.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.9","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"104.8","Single Cell Type RNA - Fibroblasts [nTPM]":"110.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"111.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1498.3","Single Cell Type RNA - granulocytes [nTPM]":"255.9","Single Cell Type RNA - Granulosa cells [nTPM]":"2.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"48.5","Single Cell Type RNA - Hepatocytes [nTPM]":"13.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"45.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"38.6","Single Cell Type RNA - Ionocytes [nTPM]":"67.1","Single Cell Type RNA - Kupffer cells [nTPM]":"125.2","Single Cell Type RNA - Langerhans cells [nTPM]":"461.8","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"6.8","Single Cell Type RNA - Macrophages [nTPM]":"596.6","Single Cell Type RNA - Melanocytes [nTPM]":"129.9","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"59.1","Single Cell Type RNA - Muller glia cells [nTPM]":"1.7","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"30.5","Single Cell Type RNA - Paneth cells [nTPM]":"29.5","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"331.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"170.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"37.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"84.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"29.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"94.9","Single Cell Type RNA - Spermatocytes [nTPM]":"2.7","Single Cell Type RNA - Spermatogonia [nTPM]":"2.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"367.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"745.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.1","Single Cell Type RNA - T-cells [nTPM]":"624.2","Single Cell Type RNA - Theca cells [nTPM]":"14.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.9","Single Cell Type RNA - Urothelial cells [nTPM]":"78.1"},{"Gene":"TNIK","Gene synonym":["KIAA0551"],"Ensembl":"ENSG00000154310","Gene description":"TRAF2 and NCK interacting kinase","Uniprot":["Q9UKE5"],"Chromosome":"3","Position":"171058414-171460408","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Neurogenesis","Wnt signaling pathway"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"33.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"1074.4","Excitatory neurons":"248.4","Inhibitory neurons":"360.8","Oligodendrocyte precursor cells":"374.5","Oligodendrocytes":"205.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"65.2","HMC-1":"71.3","WM-115":"52.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012128","HPA012297"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"160000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA012128":"AB_1858226","HPA012297":"AB_1858225"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.4","Tissue RNA - adrenal gland [nTPM]":"4.4","Tissue RNA - amygdala [nTPM]":"25.7","Tissue RNA - appendix [nTPM]":"6.2","Tissue RNA - basal ganglia [nTPM]":"33.7","Tissue RNA - bone marrow [nTPM]":"4.4","Tissue RNA - breast [nTPM]":"2.1","Tissue RNA - cerebellum [nTPM]":"4.1","Tissue RNA - cerebral cortex [nTPM]":"17.5","Tissue RNA - cervix [nTPM]":"1.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"8.2","Tissue RNA - duodenum [nTPM]":"21.0","Tissue RNA - endometrium 1 [nTPM]":"3.4","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"4.1","Tissue RNA - fallopian tube [nTPM]":"2.8","Tissue RNA - gallbladder [nTPM]":"5.1","Tissue RNA - heart muscle [nTPM]":"9.4","Tissue RNA - hippocampal formation [nTPM]":"20.8","Tissue RNA - hypothalamus [nTPM]":"15.7","Tissue RNA - kidney [nTPM]":"3.8","Tissue RNA - liver [nTPM]":"3.1","Tissue RNA - lung [nTPM]":"8.9","Tissue RNA - lymph node [nTPM]":"6.7","Tissue RNA - medulla oblongata [nTPM]":"25.5","Tissue RNA - midbrain [nTPM]":"18.7","Tissue RNA - ovary [nTPM]":"1.5","Tissue RNA - pancreas [nTPM]":"3.7","Tissue RNA - parathyroid gland [nTPM]":"0.5","Tissue RNA - pituitary gland [nTPM]":"8.4","Tissue RNA - placenta [nTPM]":"1.9","Tissue RNA - pons [nTPM]":"6.3","Tissue RNA - prostate [nTPM]":"3.5","Tissue RNA - rectum [nTPM]":"6.7","Tissue RNA - retina [nTPM]":"19.4","Tissue RNA - salivary gland [nTPM]":"1.9","Tissue RNA - seminal vesicle [nTPM]":"4.6","Tissue RNA - skeletal muscle [nTPM]":"23.2","Tissue RNA - skin 1 [nTPM]":"1.0","Tissue RNA - small intestine [nTPM]":"21.3","Tissue RNA - smooth muscle [nTPM]":"4.3","Tissue RNA - spinal cord [nTPM]":"19.0","Tissue RNA - spleen [nTPM]":"4.5","Tissue RNA - stomach 1 [nTPM]":"7.0","Tissue RNA - testis [nTPM]":"7.7","Tissue RNA - thalamus [nTPM]":"20.1","Tissue RNA - thymus [nTPM]":"7.0","Tissue RNA - thyroid gland [nTPM]":"6.3","Tissue RNA - tongue [nTPM]":"23.6","Tissue RNA - tonsil [nTPM]":"5.3","Tissue RNA - urinary bladder [nTPM]":"4.8","Tissue RNA - vagina [nTPM]":"2.1","Tissue RNA - white matter [nTPM]":"10.7","Cell RNA - A-431 [nTPM]":"0.9","Cell RNA - A549 [nTPM]":"1.2","Cell RNA - AF22 [nTPM]":"43.4","Cell RNA - AN3-CA [nTPM]":"4.7","Cell RNA - ASC diff [nTPM]":"0.8","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"10.4","Cell RNA - BJ [nTPM]":"9.3","Cell RNA - BJ hTERT+ [nTPM]":"2.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.8","Cell RNA - CACO-2 [nTPM]":"41.5","Cell RNA - CAPAN-2 [nTPM]":"16.9","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"3.4","Cell RNA - fHDF\/TERT166 [nTPM]":"9.0","Cell RNA - GAMG [nTPM]":"6.9","Cell RNA - HaCaT [nTPM]":"14.1","Cell RNA - HAP1 [nTPM]":"6.3","Cell RNA - HBEC3-KT [nTPM]":"2.6","Cell RNA - HBF TERT88 [nTPM]":"7.3","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"9.8","Cell RNA - HEL [nTPM]":"65.2","Cell RNA - HeLa [nTPM]":"3.7","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"19.0","Cell RNA - HL-60 [nTPM]":"13.0","Cell RNA - HMC-1 [nTPM]":"71.3","Cell RNA - HSkMC [nTPM]":"6.1","Cell RNA - hTCEpi [nTPM]":"5.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.3","Cell RNA - hTERT-HME1 [nTPM]":"0.9","Cell RNA - hTERT-RPE1 [nTPM]":"15.7","Cell RNA - HUVEC TERT2 [nTPM]":"43.6","Cell RNA - JURKAT [nTPM]":"10.5","Cell RNA - K-562 [nTPM]":"23.3","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"1.1","Cell RNA - MCF7 [nTPM]":"1.1","Cell RNA - MOLT-4 [nTPM]":"4.1","Cell RNA - NB-4 [nTPM]":"13.5","Cell RNA - NTERA-2 [nTPM]":"18.2","Cell RNA - OE19 [nTPM]":"30.6","Cell RNA - PC-3 [nTPM]":"17.9","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"11.8","Cell RNA - RPMI-8226 [nTPM]":"16.6","Cell RNA - RPTEC TERT1 [nTPM]":"12.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"2.1","Cell RNA - SH-SY5Y [nTPM]":"2.3","Cell RNA - SiHa [nTPM]":"5.8","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"9.6","Cell RNA - SuSa [nTPM]":"4.1","Cell RNA - T-47d [nTPM]":"20.4","Cell RNA - THP-1 [nTPM]":"2.9","Cell RNA - TIME [nTPM]":"0.5","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"7.9","Cell RNA - U-2197 [nTPM]":"20.5","Cell RNA - U-251 MG [nTPM]":"7.1","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"1.8","Cell RNA - U-937 [nTPM]":"13.8","Cell RNA - WM-115 [nTPM]":"52.1","Blood RNA - basophil [nTPM]":"4.6","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"10.5","Blood RNA - gdT-cell [nTPM]":"3.5","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"4.4","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"4.2","Blood RNA - memory CD8 T-cell [nTPM]":"3.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"5.8","Blood RNA - naive CD8 T-cell [nTPM]":"3.1","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"2.4","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"5.3","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"25.7","Brain RNA - basal ganglia [nTPM]":"33.7","Brain RNA - cerebellum [nTPM]":"4.1","Brain RNA - cerebral cortex [nTPM]":"17.5","Brain RNA - hippocampal formation [nTPM]":"20.8","Brain RNA - hypothalamus [nTPM]":"15.7","Brain RNA - medulla oblongata [nTPM]":"25.5","Brain RNA - midbrain [nTPM]":"18.7","Brain RNA - pons [nTPM]":"6.3","Brain RNA - spinal cord [nTPM]":"19.0","Brain RNA - thalamus [nTPM]":"20.1","Brain RNA - white matter [nTPM]":"10.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"50.4","Single Cell Type RNA - Astrocytes [nTPM]":"1074.4","Single Cell Type RNA - B-cells [nTPM]":"4.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"19.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"28.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"7.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.3","Single Cell Type RNA - dendritic cells [nTPM]":"32.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"19.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"12.1","Single Cell Type RNA - Early spermatids [nTPM]":"48.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.5","Single Cell Type RNA - Endothelial cells [nTPM]":"1.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.2","Single Cell Type RNA - Erythroid cells [nTPM]":"13.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"248.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.3","Single Cell Type RNA - Fibroblasts [nTPM]":"9.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"83.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"8.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"360.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"6.5","Single Cell Type RNA - Langerhans cells [nTPM]":"1.9","Single Cell Type RNA - Late spermatids [nTPM]":"38.0","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"10.4","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"57.1","Single Cell Type RNA - monocytes [nTPM]":"1.6","Single Cell Type RNA - Muller glia cells [nTPM]":"65.0","Single Cell Type RNA - NK-cells [nTPM]":"51.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"374.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"205.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.1","Single Cell Type RNA - Paneth cells [nTPM]":"21.6","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"11.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"56.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"28.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.2","Single Cell Type RNA - Spermatocytes [nTPM]":"3.1","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - T-cells [nTPM]":"47.4","Single Cell Type RNA - Theca cells [nTPM]":"9.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.6","Single Cell Type RNA - Urothelial cells [nTPM]":"3.2"},{"Gene":"TNNI3K","Gene synonym":["CARK"],"Ensembl":"ENSG00000116783","Gene description":"TNNI3 interacting kinase","Uniprot":["Q59H18"],"Chromosome":"1","Position":"74235387-74544428","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cardiomyopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"heart muscle":"58.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"27.0","Early spermatids":"32.0","Late spermatids":"6.6","Proximal tubular cells":"8.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"1.0"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.77e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.8","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"3.6","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"3.6","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"1.4","Tissue RNA - cerebellum [nTPM]":"4.9","Tissue RNA - cerebral cortex [nTPM]":"7.2","Tissue RNA - cervix [nTPM]":"1.0","Tissue RNA - choroid plexus [nTPM]":"2.0","Tissue RNA - colon [nTPM]":"2.0","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"1.3","Tissue RNA - epididymis [nTPM]":"2.5","Tissue RNA - esophagus [nTPM]":"0.6","Tissue RNA - fallopian tube [nTPM]":"1.5","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"58.7","Tissue RNA - hippocampal formation [nTPM]":"3.7","Tissue RNA - hypothalamus [nTPM]":"3.9","Tissue RNA - kidney [nTPM]":"3.4","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"0.9","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"3.3","Tissue RNA - midbrain [nTPM]":"3.2","Tissue RNA - ovary [nTPM]":"1.5","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"2.3","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"3.6","Tissue RNA - prostate [nTPM]":"1.1","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"5.2","Tissue RNA - salivary gland [nTPM]":"0.8","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"1.5","Tissue RNA - skin 1 [nTPM]":"1.6","Tissue RNA - small intestine [nTPM]":"0.8","Tissue RNA - smooth muscle [nTPM]":"0.9","Tissue RNA - spinal cord [nTPM]":"3.5","Tissue RNA - spleen [nTPM]":"1.4","Tissue RNA - stomach 1 [nTPM]":"1.1","Tissue RNA - testis [nTPM]":"4.0","Tissue RNA - thalamus [nTPM]":"3.5","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"1.0","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"1.4","Tissue RNA - vagina [nTPM]":"0.9","Tissue RNA - white matter [nTPM]":"4.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"1.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.7","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.3","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.8","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.7","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.6","Brain RNA - basal ganglia [nTPM]":"3.6","Brain RNA - cerebellum [nTPM]":"4.9","Brain RNA - cerebral cortex [nTPM]":"7.2","Brain RNA - hippocampal formation [nTPM]":"3.7","Brain RNA - hypothalamus [nTPM]":"3.9","Brain RNA - medulla oblongata [nTPM]":"3.3","Brain RNA - midbrain [nTPM]":"3.2","Brain RNA - pons [nTPM]":"3.6","Brain RNA - spinal cord [nTPM]":"3.5","Brain RNA - thalamus [nTPM]":"3.5","Brain RNA - white matter [nTPM]":"4.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"27.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"32.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"6.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"TOP3A","Gene synonym":["TOP3","ZGRF7"],"Ensembl":"ENSG00000177302","Gene description":"DNA topoisomerase III alpha","Uniprot":["Q13472"],"Chromosome":"17","Position":"18271428-18315007","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["DNA-binding","Isomerase","Topoisomerase"],"Disease involvement":["Cancer-related genes","Disease variant","Dwarfism","Primary mitochondrial disease","Progressive external ophthalmoplegia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"39.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002449"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002449":"AB_564037"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.24e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.39e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.59e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.4","Tissue RNA - adrenal gland [nTPM]":"8.0","Tissue RNA - amygdala [nTPM]":"1.9","Tissue RNA - appendix [nTPM]":"3.3","Tissue RNA - basal ganglia [nTPM]":"1.8","Tissue RNA - bone marrow [nTPM]":"5.7","Tissue RNA - breast [nTPM]":"8.6","Tissue RNA - cerebellum [nTPM]":"3.1","Tissue RNA - cerebral cortex [nTPM]":"2.6","Tissue RNA - cervix [nTPM]":"8.6","Tissue RNA - choroid plexus [nTPM]":"2.1","Tissue RNA - colon [nTPM]":"7.8","Tissue RNA - duodenum [nTPM]":"2.3","Tissue RNA - endometrium 1 [nTPM]":"8.4","Tissue RNA - epididymis [nTPM]":"1.6","Tissue RNA - esophagus [nTPM]":"8.6","Tissue RNA - fallopian tube [nTPM]":"8.5","Tissue RNA - gallbladder [nTPM]":"2.1","Tissue RNA - heart muscle [nTPM]":"6.0","Tissue RNA - hippocampal formation [nTPM]":"1.8","Tissue RNA - hypothalamus [nTPM]":"1.8","Tissue RNA - kidney [nTPM]":"7.0","Tissue RNA - liver [nTPM]":"11.2","Tissue RNA - lung [nTPM]":"7.7","Tissue RNA - lymph node [nTPM]":"3.6","Tissue RNA - medulla oblongata [nTPM]":"1.7","Tissue RNA - midbrain [nTPM]":"1.6","Tissue RNA - ovary [nTPM]":"7.5","Tissue RNA - pancreas [nTPM]":"7.7","Tissue RNA - parathyroid gland [nTPM]":"2.6","Tissue RNA - pituitary gland [nTPM]":"8.9","Tissue RNA - placenta [nTPM]":"2.5","Tissue RNA - pons [nTPM]":"1.7","Tissue RNA - prostate [nTPM]":"7.7","Tissue RNA - rectum [nTPM]":"2.4","Tissue RNA - retina [nTPM]":"2.1","Tissue RNA - salivary gland [nTPM]":"8.1","Tissue RNA - seminal vesicle [nTPM]":"1.7","Tissue RNA - skeletal muscle [nTPM]":"10.0","Tissue RNA - skin 1 [nTPM]":"11.3","Tissue RNA - small intestine [nTPM]":"8.2","Tissue RNA - smooth muscle [nTPM]":"2.6","Tissue RNA - spinal cord [nTPM]":"1.4","Tissue RNA - spleen [nTPM]":"11.4","Tissue RNA - stomach 1 [nTPM]":"7.6","Tissue RNA - testis [nTPM]":"11.7","Tissue RNA - thalamus [nTPM]":"2.0","Tissue RNA - thymus [nTPM]":"4.2","Tissue RNA - thyroid gland [nTPM]":"6.7","Tissue RNA - tongue [nTPM]":"2.5","Tissue RNA - tonsil [nTPM]":"3.3","Tissue RNA - urinary bladder [nTPM]":"8.5","Tissue RNA - vagina [nTPM]":"7.8","Tissue RNA - white matter [nTPM]":"2.0","Cell RNA - A-431 [nTPM]":"9.3","Cell RNA - A549 [nTPM]":"14.2","Cell RNA - AF22 [nTPM]":"9.4","Cell RNA - AN3-CA [nTPM]":"11.1","Cell RNA - ASC diff [nTPM]":"3.8","Cell RNA - ASC TERT1 [nTPM]":"4.6","Cell RNA - BEWO [nTPM]":"10.9","Cell RNA - BJ [nTPM]":"9.4","Cell RNA - BJ hTERT+ [nTPM]":"4.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.8","Cell RNA - CACO-2 [nTPM]":"22.4","Cell RNA - CAPAN-2 [nTPM]":"3.4","Cell RNA - Daudi [nTPM]":"13.7","Cell RNA - EFO-21 [nTPM]":"6.0","Cell RNA - fHDF\/TERT166 [nTPM]":"6.5","Cell RNA - GAMG [nTPM]":"6.6","Cell RNA - HaCaT [nTPM]":"11.7","Cell RNA - HAP1 [nTPM]":"12.6","Cell RNA - HBEC3-KT [nTPM]":"6.7","Cell RNA - HBF TERT88 [nTPM]":"11.5","Cell RNA - HDLM-2 [nTPM]":"11.6","Cell RNA - HEK 293 [nTPM]":"11.4","Cell RNA - HEL [nTPM]":"13.1","Cell RNA - HeLa [nTPM]":"15.2","Cell RNA - Hep G2 [nTPM]":"7.9","Cell RNA - HHSteC [nTPM]":"4.3","Cell RNA - HL-60 [nTPM]":"5.8","Cell RNA - HMC-1 [nTPM]":"11.9","Cell RNA - HSkMC [nTPM]":"2.9","Cell RNA - hTCEpi [nTPM]":"4.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.0","Cell RNA - hTERT-HME1 [nTPM]":"8.7","Cell RNA - hTERT-RPE1 [nTPM]":"2.9","Cell RNA - HUVEC TERT2 [nTPM]":"7.3","Cell RNA - JURKAT [nTPM]":"11.5","Cell RNA - K-562 [nTPM]":"11.3","Cell RNA - Karpas-707 [nTPM]":"5.7","Cell RNA - LHCN-M2 [nTPM]":"6.1","Cell RNA - MCF7 [nTPM]":"6.4","Cell RNA - MOLT-4 [nTPM]":"15.2","Cell RNA - NB-4 [nTPM]":"5.9","Cell RNA - NTERA-2 [nTPM]":"8.7","Cell RNA - OE19 [nTPM]":"13.8","Cell RNA - PC-3 [nTPM]":"6.8","Cell RNA - REH [nTPM]":"17.4","Cell RNA - RH-30 [nTPM]":"22.6","Cell RNA - RPMI-8226 [nTPM]":"14.8","Cell RNA - RPTEC TERT1 [nTPM]":"3.2","Cell RNA - RT4 [nTPM]":"8.1","Cell RNA - SCLC-21H [nTPM]":"7.7","Cell RNA - SH-SY5Y [nTPM]":"13.6","Cell RNA - SiHa [nTPM]":"12.6","Cell RNA - SK-BR-3 [nTPM]":"8.3","Cell RNA - SK-MEL-30 [nTPM]":"8.4","Cell RNA - SuSa [nTPM]":"24.5","Cell RNA - T-47d [nTPM]":"16.1","Cell RNA - THP-1 [nTPM]":"6.5","Cell RNA - TIME [nTPM]":"6.5","Cell RNA - U-138 MG [nTPM]":"10.6","Cell RNA - U-2 OS [nTPM]":"8.1","Cell RNA - U-2197 [nTPM]":"18.2","Cell RNA - U-251 MG [nTPM]":"15.4","Cell RNA - U-266\/70 [nTPM]":"5.8","Cell RNA - U-266\/84 [nTPM]":"13.7","Cell RNA - U-698 [nTPM]":"10.4","Cell RNA - U-87 MG [nTPM]":"6.6","Cell RNA - U-937 [nTPM]":"8.0","Cell RNA - WM-115 [nTPM]":"10.5","Blood RNA - basophil [nTPM]":"1.1","Blood RNA - classical monocyte [nTPM]":"3.1","Blood RNA - eosinophil [nTPM]":"3.4","Blood RNA - gdT-cell [nTPM]":"1.8","Blood RNA - intermediate monocyte [nTPM]":"2.7","Blood RNA - MAIT T-cell [nTPM]":"1.3","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"1.6","Blood RNA - myeloid DC [nTPM]":"1.3","Blood RNA - naive B-cell [nTPM]":"0.8","Blood RNA - naive CD4 T-cell [nTPM]":"1.1","Blood RNA - naive CD8 T-cell [nTPM]":"1.2","Blood RNA - neutrophil [nTPM]":"4.2","Blood RNA - NK-cell [nTPM]":"2.2","Blood RNA - non-classical monocyte [nTPM]":"1.5","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"2.0","Brain RNA - amygdala [nTPM]":"1.9","Brain RNA - basal ganglia [nTPM]":"1.8","Brain RNA - cerebellum [nTPM]":"3.1","Brain RNA - cerebral cortex [nTPM]":"2.6","Brain RNA - hippocampal formation [nTPM]":"1.8","Brain RNA - hypothalamus [nTPM]":"1.8","Brain RNA - medulla oblongata [nTPM]":"1.7","Brain RNA - midbrain [nTPM]":"1.6","Brain RNA - pons [nTPM]":"1.7","Brain RNA - spinal cord [nTPM]":"1.4","Brain RNA - thalamus [nTPM]":"2.0","Brain RNA - white matter [nTPM]":"2.0","Single Cell Type RNA - Adipocytes [nTPM]":"5.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"6.5","Single Cell Type RNA - B-cells [nTPM]":"9.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"20.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"7.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.4","Single Cell Type RNA - dendritic cells [nTPM]":"11.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.2","Single Cell Type RNA - Early spermatids [nTPM]":"7.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.7","Single Cell Type RNA - Endothelial cells [nTPM]":"6.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"9.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.9","Single Cell Type RNA - Fibroblasts [nTPM]":"6.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.3","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"12.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"7.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.4","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.2","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"12.4","Single Cell Type RNA - Langerhans cells [nTPM]":"6.3","Single Cell Type RNA - Late spermatids [nTPM]":"7.9","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"11.6","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"13.9","Single Cell Type RNA - Muller glia cells [nTPM]":"6.4","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.6","Single Cell Type RNA - Paneth cells [nTPM]":"2.8","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"12.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"22.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.6","Single Cell Type RNA - Spermatocytes [nTPM]":"26.7","Single Cell Type RNA - Spermatogonia [nTPM]":"25.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.4","Single Cell Type RNA - T-cells [nTPM]":"9.0","Single Cell Type RNA - Theca cells [nTPM]":"13.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.9","Single Cell Type RNA - Urothelial cells [nTPM]":"5.0"},{"Gene":"TOPORS","Gene synonym":["LUN","RP31","TP53BPL"],"Ensembl":"ENSG00000197579","Gene description":"TOP1 binding arginine\/serine rich protein, E3 ubiquitin ligase","Uniprot":["Q9NS56"],"Chromosome":"9","Position":"32540544-32552586","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"169.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"67.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"67.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"90.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060640","HPA065661"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA060640":"AB_2684334","HPA065661":"AB_2685527"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.07e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.64e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.8","Tissue RNA - adrenal gland [nTPM]":"9.8","Tissue RNA - amygdala [nTPM]":"5.4","Tissue RNA - appendix [nTPM]":"8.4","Tissue RNA - basal ganglia [nTPM]":"6.3","Tissue RNA - bone marrow [nTPM]":"25.2","Tissue RNA - breast [nTPM]":"12.4","Tissue RNA - cerebellum [nTPM]":"10.5","Tissue RNA - cerebral cortex [nTPM]":"8.5","Tissue RNA - cervix [nTPM]":"10.3","Tissue RNA - choroid plexus [nTPM]":"7.3","Tissue RNA - colon [nTPM]":"9.2","Tissue RNA - duodenum [nTPM]":"8.3","Tissue RNA - endometrium 1 [nTPM]":"11.4","Tissue RNA - epididymis [nTPM]":"10.0","Tissue RNA - esophagus [nTPM]":"9.9","Tissue RNA - fallopian tube [nTPM]":"7.6","Tissue RNA - gallbladder [nTPM]":"8.7","Tissue RNA - heart muscle [nTPM]":"6.8","Tissue RNA - hippocampal formation [nTPM]":"5.4","Tissue RNA - hypothalamus [nTPM]":"6.6","Tissue RNA - kidney [nTPM]":"13.2","Tissue RNA - liver [nTPM]":"16.2","Tissue RNA - lung [nTPM]":"9.3","Tissue RNA - lymph node [nTPM]":"9.3","Tissue RNA - medulla oblongata [nTPM]":"6.1","Tissue RNA - midbrain [nTPM]":"6.1","Tissue RNA - ovary [nTPM]":"15.3","Tissue RNA - pancreas [nTPM]":"8.6","Tissue RNA - parathyroid gland [nTPM]":"14.0","Tissue RNA - pituitary gland [nTPM]":"6.9","Tissue RNA - placenta [nTPM]":"10.0","Tissue RNA - pons [nTPM]":"6.2","Tissue RNA - prostate [nTPM]":"11.2","Tissue RNA - rectum [nTPM]":"9.3","Tissue RNA - retina [nTPM]":"11.5","Tissue RNA - salivary gland [nTPM]":"7.6","Tissue RNA - seminal vesicle [nTPM]":"9.3","Tissue RNA - skeletal muscle [nTPM]":"7.2","Tissue RNA - skin 1 [nTPM]":"9.6","Tissue RNA - small intestine [nTPM]":"8.8","Tissue RNA - smooth muscle [nTPM]":"11.2","Tissue RNA - spinal cord [nTPM]":"5.9","Tissue RNA - spleen [nTPM]":"10.5","Tissue RNA - stomach 1 [nTPM]":"8.9","Tissue RNA - testis [nTPM]":"14.8","Tissue RNA - thalamus [nTPM]":"6.6","Tissue RNA - thymus [nTPM]":"14.5","Tissue RNA - thyroid gland [nTPM]":"14.1","Tissue RNA - tongue [nTPM]":"10.4","Tissue RNA - tonsil [nTPM]":"10.1","Tissue RNA - urinary bladder [nTPM]":"10.3","Tissue RNA - vagina [nTPM]":"7.2","Tissue RNA - white matter [nTPM]":"8.3","Cell RNA - A-431 [nTPM]":"16.6","Cell RNA - A549 [nTPM]":"15.1","Cell RNA - AF22 [nTPM]":"20.4","Cell RNA - AN3-CA [nTPM]":"17.9","Cell RNA - ASC diff [nTPM]":"24.4","Cell RNA - ASC TERT1 [nTPM]":"21.8","Cell RNA - BEWO [nTPM]":"12.9","Cell RNA - BJ [nTPM]":"20.7","Cell RNA - BJ hTERT+ [nTPM]":"19.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.5","Cell RNA - CACO-2 [nTPM]":"9.5","Cell RNA - CAPAN-2 [nTPM]":"8.3","Cell RNA - Daudi [nTPM]":"26.8","Cell RNA - EFO-21 [nTPM]":"11.7","Cell RNA - fHDF\/TERT166 [nTPM]":"20.8","Cell RNA - GAMG [nTPM]":"14.8","Cell RNA - HaCaT [nTPM]":"10.9","Cell RNA - HAP1 [nTPM]":"24.2","Cell RNA - HBEC3-KT [nTPM]":"23.5","Cell RNA - HBF TERT88 [nTPM]":"23.6","Cell RNA - HDLM-2 [nTPM]":"22.5","Cell RNA - HEK 293 [nTPM]":"13.3","Cell RNA - HEL [nTPM]":"90.8","Cell RNA - HeLa [nTPM]":"25.2","Cell RNA - Hep G2 [nTPM]":"11.9","Cell RNA - HHSteC [nTPM]":"15.1","Cell RNA - HL-60 [nTPM]":"26.1","Cell RNA - HMC-1 [nTPM]":"24.0","Cell RNA - HSkMC [nTPM]":"17.9","Cell RNA - hTCEpi [nTPM]":"25.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"24.4","Cell RNA - hTERT-HME1 [nTPM]":"17.1","Cell RNA - hTERT-RPE1 [nTPM]":"20.9","Cell RNA - HUVEC TERT2 [nTPM]":"20.8","Cell RNA - JURKAT [nTPM]":"20.1","Cell RNA - K-562 [nTPM]":"16.1","Cell RNA - Karpas-707 [nTPM]":"13.6","Cell RNA - LHCN-M2 [nTPM]":"27.9","Cell RNA - MCF7 [nTPM]":"8.9","Cell RNA - MOLT-4 [nTPM]":"23.5","Cell RNA - NB-4 [nTPM]":"47.6","Cell RNA - NTERA-2 [nTPM]":"27.2","Cell RNA - OE19 [nTPM]":"12.3","Cell RNA - PC-3 [nTPM]":"15.2","Cell RNA - REH [nTPM]":"23.9","Cell RNA - RH-30 [nTPM]":"18.1","Cell RNA - RPMI-8226 [nTPM]":"12.2","Cell RNA - RPTEC TERT1 [nTPM]":"22.5","Cell RNA - RT4 [nTPM]":"17.2","Cell RNA - SCLC-21H [nTPM]":"10.1","Cell RNA - SH-SY5Y [nTPM]":"16.1","Cell RNA - SiHa [nTPM]":"20.7","Cell RNA - SK-BR-3 [nTPM]":"11.2","Cell RNA - SK-MEL-30 [nTPM]":"13.8","Cell RNA - SuSa [nTPM]":"22.9","Cell RNA - T-47d [nTPM]":"11.3","Cell RNA - THP-1 [nTPM]":"14.7","Cell RNA - TIME [nTPM]":"22.0","Cell RNA - U-138 MG [nTPM]":"18.4","Cell RNA - U-2 OS [nTPM]":"18.6","Cell RNA - U-2197 [nTPM]":"9.6","Cell RNA - U-251 MG [nTPM]":"15.5","Cell RNA - U-266\/70 [nTPM]":"9.5","Cell RNA - U-266\/84 [nTPM]":"16.2","Cell RNA - U-698 [nTPM]":"28.5","Cell RNA - U-87 MG [nTPM]":"17.0","Cell RNA - U-937 [nTPM]":"14.8","Cell RNA - WM-115 [nTPM]":"8.4","Blood RNA - basophil [nTPM]":"38.8","Blood RNA - classical monocyte [nTPM]":"10.0","Blood RNA - eosinophil [nTPM]":"21.3","Blood RNA - gdT-cell [nTPM]":"9.6","Blood RNA - intermediate monocyte [nTPM]":"9.8","Blood RNA - MAIT T-cell [nTPM]":"10.3","Blood RNA - memory B-cell [nTPM]":"9.4","Blood RNA - memory CD4 T-cell [nTPM]":"10.4","Blood RNA - memory CD8 T-cell [nTPM]":"11.4","Blood RNA - myeloid DC [nTPM]":"10.2","Blood RNA - naive B-cell [nTPM]":"10.8","Blood RNA - naive CD4 T-cell [nTPM]":"13.9","Blood RNA - naive CD8 T-cell [nTPM]":"13.8","Blood RNA - neutrophil [nTPM]":"67.6","Blood RNA - NK-cell [nTPM]":"15.0","Blood RNA - non-classical monocyte [nTPM]":"13.6","Blood RNA - plasmacytoid DC [nTPM]":"8.2","Blood RNA - T-reg [nTPM]":"13.5","Blood RNA - total PBMC [nTPM]":"7.3","Brain RNA - amygdala [nTPM]":"5.4","Brain RNA - basal ganglia [nTPM]":"6.3","Brain RNA - cerebellum [nTPM]":"10.5","Brain RNA - cerebral cortex [nTPM]":"8.5","Brain RNA - hippocampal formation [nTPM]":"5.4","Brain RNA - hypothalamus [nTPM]":"6.6","Brain RNA - medulla oblongata [nTPM]":"6.1","Brain RNA - midbrain [nTPM]":"6.1","Brain RNA - pons [nTPM]":"6.2","Brain RNA - spinal cord [nTPM]":"5.9","Brain RNA - thalamus [nTPM]":"6.6","Brain RNA - white matter [nTPM]":"8.3","Single Cell Type RNA - Adipocytes [nTPM]":"69.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"54.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"32.0","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"49.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"47.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"45.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"33.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"61.5","Single Cell Type RNA - Bipolar cells [nTPM]":"46.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"32.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"28.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"37.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"31.9","Single Cell Type RNA - dendritic cells [nTPM]":"63.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"26.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"25.1","Single Cell Type RNA - Early spermatids [nTPM]":"169.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"36.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"38.1","Single Cell Type RNA - Endothelial cells [nTPM]":"48.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"45.9","Single Cell Type RNA - Erythroid cells [nTPM]":"66.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"16.9","Single Cell Type RNA - Fibroblasts [nTPM]":"42.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"25.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"45.5","Single Cell Type RNA - granulocytes [nTPM]":"41.8","Single Cell Type RNA - Granulosa cells [nTPM]":"43.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.4","Single Cell Type RNA - Hepatocytes [nTPM]":"24.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.7","Single Cell Type RNA - Horizontal cells [nTPM]":"55.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"22.9","Single Cell Type RNA - Ionocytes [nTPM]":"44.7","Single Cell Type RNA - Kupffer cells [nTPM]":"19.1","Single Cell Type RNA - Langerhans cells [nTPM]":"35.3","Single Cell Type RNA - Late spermatids [nTPM]":"21.8","Single Cell Type RNA - Leydig cells [nTPM]":"33.2","Single Cell Type RNA - Macrophages [nTPM]":"31.8","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"30.4","Single Cell Type RNA - Muller glia cells [nTPM]":"43.5","Single Cell Type RNA - NK-cells [nTPM]":"36.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"22.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.1","Single Cell Type RNA - Paneth cells [nTPM]":"24.3","Single Cell Type RNA - Peritubular cells [nTPM]":"32.7","Single Cell Type RNA - Plasma cells [nTPM]":"39.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"39.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"42.0","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"54.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"48.2","Single Cell Type RNA - Spermatocytes [nTPM]":"54.4","Single Cell Type RNA - Spermatogonia [nTPM]":"53.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"39.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"47.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"50.8","Single Cell Type RNA - T-cells [nTPM]":"55.4","Single Cell Type RNA - Theca cells [nTPM]":"43.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.0","Single Cell Type RNA - Urothelial cells [nTPM]":"49.8"},{"Gene":"TP53","Gene synonym":["LFS1","p53"],"Ensembl":"ENSG00000141510","Gene description":"Tumor protein p53","Uniprot":["P04637"],"Chromosome":"17","Position":"7661779-7687538","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transcription factors","Transporters"],"Biological process":["Apoptosis","Biological rhythms","Cell cycle","Host-virus interaction","Necrosis","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant","Li-Fraumeni syndrome","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002973","CAB039238","CAB039239","HPA051244","HPA063532","CAB072876","CAB079965"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 14: REH - Unknown function","Single cell expression cluster":"Cluster 32: Non-specific - Translation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Mitochondria","Cytosol"],"Antibody RRID":{"CAB002973":"AB_2206626","CAB039238":null,"CAB039239":null,"CAB072876":"AB_2665731","CAB079965":null,"HPA051244":"AB_2681403","HPA063532":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.35e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.01e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Tissue RNA - adipose tissue [nTPM]":"19.3","Tissue RNA - adrenal gland [nTPM]":"13.8","Tissue RNA - amygdala [nTPM]":"10.4","Tissue RNA - appendix [nTPM]":"27.1","Tissue RNA - basal ganglia [nTPM]":"12.6","Tissue RNA - bone marrow [nTPM]":"19.6","Tissue RNA - breast [nTPM]":"22.5","Tissue RNA - cerebellum [nTPM]":"10.4","Tissue RNA - cerebral cortex [nTPM]":"16.5","Tissue RNA - cervix [nTPM]":"19.9","Tissue RNA - choroid plexus [nTPM]":"10.3","Tissue RNA - colon [nTPM]":"29.0","Tissue RNA - duodenum [nTPM]":"18.9","Tissue RNA - endometrium 1 [nTPM]":"24.5","Tissue RNA - epididymis [nTPM]":"12.8","Tissue RNA - esophagus [nTPM]":"28.8","Tissue RNA - fallopian tube [nTPM]":"31.3","Tissue RNA - gallbladder [nTPM]":"13.2","Tissue RNA - heart muscle [nTPM]":"11.1","Tissue RNA - hippocampal formation [nTPM]":"10.1","Tissue RNA - hypothalamus [nTPM]":"11.4","Tissue RNA - kidney [nTPM]":"14.9","Tissue RNA - liver [nTPM]":"16.5","Tissue RNA - lung [nTPM]":"15.1","Tissue RNA - lymph node [nTPM]":"34.6","Tissue RNA - medulla oblongata [nTPM]":"18.7","Tissue RNA - midbrain [nTPM]":"13.6","Tissue RNA - ovary [nTPM]":"27.3","Tissue RNA - pancreas [nTPM]":"18.3","Tissue RNA - parathyroid gland [nTPM]":"9.4","Tissue RNA - pituitary gland [nTPM]":"7.3","Tissue RNA - placenta [nTPM]":"23.5","Tissue RNA - pons [nTPM]":"12.5","Tissue RNA - prostate [nTPM]":"17.7","Tissue RNA - rectum [nTPM]":"27.5","Tissue RNA - retina [nTPM]":"4.1","Tissue RNA - salivary gland [nTPM]":"18.9","Tissue RNA - seminal vesicle [nTPM]":"15.3","Tissue RNA - skeletal muscle [nTPM]":"12.3","Tissue RNA - skin 1 [nTPM]":"37.4","Tissue RNA - small intestine [nTPM]":"20.4","Tissue RNA - smooth muscle [nTPM]":"24.6","Tissue RNA - spinal cord [nTPM]":"12.6","Tissue RNA - spleen [nTPM]":"31.1","Tissue RNA - stomach 1 [nTPM]":"22.6","Tissue RNA - testis [nTPM]":"10.4","Tissue RNA - thalamus [nTPM]":"12.3","Tissue RNA - thymus [nTPM]":"47.2","Tissue RNA - thyroid gland [nTPM]":"17.4","Tissue RNA - tongue [nTPM]":"6.1","Tissue RNA - tonsil [nTPM]":"45.4","Tissue RNA - urinary bladder [nTPM]":"20.8","Tissue RNA - vagina [nTPM]":"19.9","Tissue RNA - white matter [nTPM]":"13.3","Cell RNA - A-431 [nTPM]":"81.5","Cell RNA - A549 [nTPM]":"145.3","Cell RNA - AF22 [nTPM]":"81.1","Cell RNA - AN3-CA [nTPM]":"57.3","Cell RNA - ASC diff [nTPM]":"37.3","Cell RNA - ASC TERT1 [nTPM]":"43.9","Cell RNA - BEWO [nTPM]":"82.8","Cell RNA - BJ [nTPM]":"28.4","Cell RNA - BJ hTERT+ [nTPM]":"66.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"78.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"100.2","Cell RNA - CACO-2 [nTPM]":"4.2","Cell RNA - CAPAN-2 [nTPM]":"40.6","Cell RNA - Daudi [nTPM]":"190.5","Cell RNA - EFO-21 [nTPM]":"126.9","Cell RNA - fHDF\/TERT166 [nTPM]":"58.7","Cell RNA - GAMG [nTPM]":"77.6","Cell RNA - HaCaT [nTPM]":"174.9","Cell RNA - HAP1 [nTPM]":"119.7","Cell RNA - HBEC3-KT [nTPM]":"80.4","Cell RNA - HBF TERT88 [nTPM]":"72.8","Cell RNA - HDLM-2 [nTPM]":"42.7","Cell RNA - HEK 293 [nTPM]":"76.5","Cell RNA - HEL [nTPM]":"77.6","Cell RNA - HeLa [nTPM]":"76.8","Cell RNA - Hep G2 [nTPM]":"70.9","Cell RNA - HHSteC [nTPM]":"111.5","Cell RNA - HL-60 [nTPM]":"1.6","Cell RNA - HMC-1 [nTPM]":"37.0","Cell RNA - HSkMC [nTPM]":"55.7","Cell RNA - hTCEpi [nTPM]":"93.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"38.9","Cell RNA - hTERT-HME1 [nTPM]":"106.5","Cell RNA - hTERT-RPE1 [nTPM]":"45.6","Cell RNA - HUVEC TERT2 [nTPM]":"79.4","Cell RNA - JURKAT [nTPM]":"24.7","Cell RNA - K-562 [nTPM]":"3.8","Cell RNA - Karpas-707 [nTPM]":"6.9","Cell RNA - LHCN-M2 [nTPM]":"41.5","Cell RNA - MCF7 [nTPM]":"145.1","Cell RNA - MOLT-4 [nTPM]":"130.0","Cell RNA - NB-4 [nTPM]":"96.3","Cell RNA - NTERA-2 [nTPM]":"80.2","Cell RNA - OE19 [nTPM]":"10.4","Cell RNA - PC-3 [nTPM]":"2.4","Cell RNA - REH [nTPM]":"252.2","Cell RNA - RH-30 [nTPM]":"56.1","Cell RNA - RPMI-8226 [nTPM]":"66.2","Cell RNA - RPTEC TERT1 [nTPM]":"59.4","Cell RNA - RT4 [nTPM]":"87.3","Cell RNA - SCLC-21H [nTPM]":"46.0","Cell RNA - SH-SY5Y [nTPM]":"80.5","Cell RNA - SiHa [nTPM]":"94.1","Cell RNA - SK-BR-3 [nTPM]":"62.6","Cell RNA - SK-MEL-30 [nTPM]":"24.3","Cell RNA - SuSa [nTPM]":"39.4","Cell RNA - T-47d [nTPM]":"109.2","Cell RNA - THP-1 [nTPM]":"7.4","Cell RNA - TIME [nTPM]":"100.7","Cell RNA - U-138 MG [nTPM]":"91.6","Cell RNA - U-2 OS [nTPM]":"30.2","Cell RNA - U-2197 [nTPM]":"1.0","Cell RNA - U-251 MG [nTPM]":"48.3","Cell RNA - U-266\/70 [nTPM]":"47.6","Cell RNA - U-266\/84 [nTPM]":"37.9","Cell RNA - U-698 [nTPM]":"82.5","Cell RNA - U-87 MG [nTPM]":"23.6","Cell RNA - U-937 [nTPM]":"9.7","Cell RNA - WM-115 [nTPM]":"80.1","Blood RNA - basophil [nTPM]":"1.2","Blood RNA - classical monocyte [nTPM]":"21.2","Blood RNA - eosinophil [nTPM]":"3.4","Blood RNA - gdT-cell [nTPM]":"13.0","Blood RNA - intermediate monocyte [nTPM]":"21.7","Blood RNA - MAIT T-cell [nTPM]":"15.9","Blood RNA - memory B-cell [nTPM]":"21.5","Blood RNA - memory CD4 T-cell [nTPM]":"13.3","Blood RNA - memory CD8 T-cell [nTPM]":"14.6","Blood RNA - myeloid DC [nTPM]":"30.3","Blood RNA - naive B-cell [nTPM]":"19.1","Blood RNA - naive CD4 T-cell [nTPM]":"13.7","Blood RNA - naive CD8 T-cell [nTPM]":"15.4","Blood RNA - neutrophil [nTPM]":"2.4","Blood RNA - NK-cell [nTPM]":"17.5","Blood RNA - non-classical monocyte [nTPM]":"19.3","Blood RNA - plasmacytoid DC [nTPM]":"27.3","Blood RNA - T-reg [nTPM]":"17.3","Blood RNA - total PBMC [nTPM]":"14.7","Brain RNA - amygdala [nTPM]":"10.4","Brain RNA - basal ganglia [nTPM]":"12.6","Brain RNA - cerebellum [nTPM]":"10.4","Brain RNA - cerebral cortex [nTPM]":"16.5","Brain RNA - hippocampal formation [nTPM]":"10.1","Brain RNA - hypothalamus [nTPM]":"11.4","Brain RNA - medulla oblongata [nTPM]":"18.7","Brain RNA - midbrain [nTPM]":"13.6","Brain RNA - pons [nTPM]":"12.5","Brain RNA - spinal cord [nTPM]":"12.6","Brain RNA - thalamus [nTPM]":"12.3","Brain RNA - white matter [nTPM]":"13.3","Single Cell Type RNA - Adipocytes [nTPM]":"21.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.8","Single Cell Type RNA - Astrocytes [nTPM]":"16.3","Single Cell Type RNA - B-cells [nTPM]":"26.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"28.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"24.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"2.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"36.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"15.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"36.9","Single Cell Type RNA - dendritic cells [nTPM]":"24.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"24.8","Single Cell Type RNA - Early spermatids [nTPM]":"12.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.0","Single Cell Type RNA - Endothelial cells [nTPM]":"24.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"30.7","Single Cell Type RNA - Erythroid cells [nTPM]":"21.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"39.6","Single Cell Type RNA - Fibroblasts [nTPM]":"17.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"31.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.1","Single Cell Type RNA - Hepatocytes [nTPM]":"18.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"43.0","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"27.8","Single Cell Type RNA - Langerhans cells [nTPM]":"20.1","Single Cell Type RNA - Late spermatids [nTPM]":"3.8","Single Cell Type RNA - Leydig cells [nTPM]":"23.0","Single Cell Type RNA - Macrophages [nTPM]":"19.3","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"31.9","Single Cell Type RNA - Muller glia cells [nTPM]":"4.9","Single Cell Type RNA - NK-cells [nTPM]":"25.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.8","Single Cell Type RNA - Paneth cells [nTPM]":"16.4","Single Cell Type RNA - Peritubular cells [nTPM]":"17.0","Single Cell Type RNA - Plasma cells [nTPM]":"7.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"25.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"4.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"32.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.4","Single Cell Type RNA - T-cells [nTPM]":"16.5","Single Cell Type RNA - Theca cells [nTPM]":"27.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"54.1","Single Cell Type RNA - Urothelial cells [nTPM]":"11.5"},{"Gene":"TP53RK","Gene synonym":["BUD32","C20orf64","dJ101A2.2","Nori-2p","prpk","TPRKB"],"Ensembl":"ENSG00000172315","Gene description":"TP53 regulating kinase","Uniprot":["Q96S44"],"Chromosome":"20","Position":"46684365-46689444","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["tRNA processing"],"Molecular function":["Hydrolase","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"214.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"212.4","SK-MEL-30":"90.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004688","HPA015837"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB004688":"AB_426116","HPA015837":"AB_1855776"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.70e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.27e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.16e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.5","Tissue RNA - adrenal gland [nTPM]":"7.7","Tissue RNA - amygdala [nTPM]":"6.0","Tissue RNA - appendix [nTPM]":"7.3","Tissue RNA - basal ganglia [nTPM]":"5.3","Tissue RNA - bone marrow [nTPM]":"6.3","Tissue RNA - breast [nTPM]":"8.9","Tissue RNA - cerebellum [nTPM]":"4.7","Tissue RNA - cerebral cortex [nTPM]":"6.1","Tissue RNA - cervix [nTPM]":"6.9","Tissue RNA - choroid plexus [nTPM]":"2.6","Tissue RNA - colon [nTPM]":"6.5","Tissue RNA - duodenum [nTPM]":"4.8","Tissue RNA - endometrium 1 [nTPM]":"7.0","Tissue RNA - epididymis [nTPM]":"4.6","Tissue RNA - esophagus [nTPM]":"8.8","Tissue RNA - fallopian tube [nTPM]":"6.3","Tissue RNA - gallbladder [nTPM]":"5.7","Tissue RNA - heart muscle [nTPM]":"5.1","Tissue RNA - hippocampal formation [nTPM]":"5.0","Tissue RNA - hypothalamus [nTPM]":"6.1","Tissue RNA - kidney [nTPM]":"6.8","Tissue RNA - liver [nTPM]":"7.0","Tissue RNA - lung [nTPM]":"5.7","Tissue RNA - lymph node [nTPM]":"11.2","Tissue RNA - medulla oblongata [nTPM]":"5.1","Tissue RNA - midbrain [nTPM]":"5.3","Tissue RNA - ovary [nTPM]":"6.2","Tissue RNA - pancreas [nTPM]":"5.4","Tissue RNA - parathyroid gland [nTPM]":"7.4","Tissue RNA - pituitary gland [nTPM]":"6.2","Tissue RNA - placenta [nTPM]":"6.0","Tissue RNA - pons [nTPM]":"5.0","Tissue RNA - prostate [nTPM]":"7.9","Tissue RNA - rectum [nTPM]":"6.0","Tissue RNA - retina [nTPM]":"6.4","Tissue RNA - salivary gland [nTPM]":"7.1","Tissue RNA - seminal vesicle [nTPM]":"6.1","Tissue RNA - skeletal muscle [nTPM]":"6.7","Tissue RNA - skin 1 [nTPM]":"9.6","Tissue RNA - small intestine [nTPM]":"5.9","Tissue RNA - smooth muscle [nTPM]":"6.8","Tissue RNA - spinal cord [nTPM]":"4.8","Tissue RNA - spleen [nTPM]":"7.0","Tissue RNA - stomach 1 [nTPM]":"7.0","Tissue RNA - testis [nTPM]":"12.1","Tissue RNA - thalamus [nTPM]":"6.9","Tissue RNA - thymus [nTPM]":"13.2","Tissue RNA - thyroid gland [nTPM]":"8.0","Tissue RNA - tongue [nTPM]":"5.3","Tissue RNA - tonsil [nTPM]":"11.9","Tissue RNA - urinary bladder [nTPM]":"10.6","Tissue RNA - vagina [nTPM]":"6.8","Tissue RNA - white matter [nTPM]":"6.5","Cell RNA - A-431 [nTPM]":"12.7","Cell RNA - A549 [nTPM]":"8.7","Cell RNA - AF22 [nTPM]":"17.9","Cell RNA - AN3-CA [nTPM]":"15.9","Cell RNA - ASC diff [nTPM]":"18.5","Cell RNA - ASC TERT1 [nTPM]":"15.1","Cell RNA - BEWO [nTPM]":"16.6","Cell RNA - BJ [nTPM]":"17.7","Cell RNA - BJ hTERT+ [nTPM]":"16.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"22.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.4","Cell RNA - CACO-2 [nTPM]":"24.7","Cell RNA - CAPAN-2 [nTPM]":"8.0","Cell RNA - Daudi [nTPM]":"32.2","Cell RNA - EFO-21 [nTPM]":"26.1","Cell RNA - fHDF\/TERT166 [nTPM]":"14.6","Cell RNA - GAMG [nTPM]":"20.3","Cell RNA - HaCaT [nTPM]":"19.6","Cell RNA - HAP1 [nTPM]":"23.1","Cell RNA - HBEC3-KT [nTPM]":"20.3","Cell RNA - HBF TERT88 [nTPM]":"19.6","Cell RNA - HDLM-2 [nTPM]":"7.9","Cell RNA - HEK 293 [nTPM]":"12.0","Cell RNA - HEL [nTPM]":"31.0","Cell RNA - HeLa [nTPM]":"8.4","Cell RNA - Hep G2 [nTPM]":"22.4","Cell RNA - HHSteC [nTPM]":"24.3","Cell RNA - HL-60 [nTPM]":"20.2","Cell RNA - HMC-1 [nTPM]":"212.4","Cell RNA - HSkMC [nTPM]":"20.3","Cell RNA - hTCEpi [nTPM]":"24.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.8","Cell RNA - hTERT-HME1 [nTPM]":"15.4","Cell RNA - hTERT-RPE1 [nTPM]":"10.6","Cell RNA - HUVEC TERT2 [nTPM]":"15.3","Cell RNA - JURKAT [nTPM]":"12.7","Cell RNA - K-562 [nTPM]":"21.5","Cell RNA - Karpas-707 [nTPM]":"13.1","Cell RNA - LHCN-M2 [nTPM]":"19.6","Cell RNA - MCF7 [nTPM]":"19.1","Cell RNA - MOLT-4 [nTPM]":"31.0","Cell RNA - NB-4 [nTPM]":"35.5","Cell RNA - NTERA-2 [nTPM]":"14.6","Cell RNA - OE19 [nTPM]":"18.1","Cell RNA - PC-3 [nTPM]":"29.8","Cell RNA - REH [nTPM]":"17.9","Cell RNA - RH-30 [nTPM]":"16.2","Cell RNA - RPMI-8226 [nTPM]":"19.1","Cell RNA - RPTEC TERT1 [nTPM]":"15.2","Cell RNA - RT4 [nTPM]":"14.1","Cell RNA - SCLC-21H [nTPM]":"21.6","Cell RNA - SH-SY5Y [nTPM]":"11.5","Cell RNA - SiHa [nTPM]":"21.3","Cell RNA - SK-BR-3 [nTPM]":"42.1","Cell RNA - SK-MEL-30 [nTPM]":"90.7","Cell RNA - SuSa [nTPM]":"9.3","Cell RNA - T-47d [nTPM]":"15.4","Cell RNA - THP-1 [nTPM]":"21.8","Cell RNA - TIME [nTPM]":"15.7","Cell RNA - U-138 MG [nTPM]":"26.3","Cell RNA - U-2 OS [nTPM]":"15.5","Cell RNA - U-2197 [nTPM]":"17.5","Cell RNA - U-251 MG [nTPM]":"19.8","Cell RNA - U-266\/70 [nTPM]":"14.5","Cell RNA - U-266\/84 [nTPM]":"19.6","Cell RNA - U-698 [nTPM]":"24.7","Cell RNA - U-87 MG [nTPM]":"15.2","Cell RNA - U-937 [nTPM]":"15.2","Cell RNA - WM-115 [nTPM]":"12.6","Blood RNA - basophil [nTPM]":"36.6","Blood RNA - classical monocyte [nTPM]":"16.1","Blood RNA - eosinophil [nTPM]":"28.4","Blood RNA - gdT-cell [nTPM]":"16.9","Blood RNA - intermediate monocyte [nTPM]":"15.8","Blood RNA - MAIT T-cell [nTPM]":"19.5","Blood RNA - memory B-cell [nTPM]":"19.9","Blood RNA - memory CD4 T-cell [nTPM]":"18.2","Blood RNA - memory CD8 T-cell [nTPM]":"19.4","Blood RNA - myeloid DC [nTPM]":"16.7","Blood RNA - naive B-cell [nTPM]":"19.3","Blood RNA - naive CD4 T-cell [nTPM]":"19.9","Blood RNA - naive CD8 T-cell [nTPM]":"17.1","Blood RNA - neutrophil [nTPM]":"2.7","Blood RNA - NK-cell [nTPM]":"22.5","Blood RNA - non-classical monocyte [nTPM]":"14.6","Blood RNA - plasmacytoid DC [nTPM]":"25.4","Blood RNA - T-reg [nTPM]":"25.5","Blood RNA - total PBMC [nTPM]":"17.4","Brain RNA - amygdala [nTPM]":"6.0","Brain RNA - basal ganglia [nTPM]":"5.3","Brain RNA - cerebellum [nTPM]":"4.7","Brain RNA - cerebral cortex [nTPM]":"6.1","Brain RNA - hippocampal formation [nTPM]":"5.0","Brain RNA - hypothalamus [nTPM]":"6.1","Brain RNA - medulla oblongata [nTPM]":"5.1","Brain RNA - midbrain [nTPM]":"5.3","Brain RNA - pons [nTPM]":"5.0","Brain RNA - spinal cord [nTPM]":"4.8","Brain RNA - thalamus [nTPM]":"6.9","Brain RNA - white matter [nTPM]":"6.5","Single Cell Type RNA - Adipocytes [nTPM]":"12.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.1","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"14.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"50.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"54.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"45.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"39.9","Single Cell Type RNA - Bipolar cells [nTPM]":"9.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"27.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"42.6","Single Cell Type RNA - dendritic cells [nTPM]":"23.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"27.4","Single Cell Type RNA - Ductal cells [nTPM]":"28.9","Single Cell Type RNA - Early spermatids [nTPM]":"214.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"25.6","Single Cell Type RNA - Endothelial cells [nTPM]":"17.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"16.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"73.6","Single Cell Type RNA - Fibroblasts [nTPM]":"29.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.2","Single Cell Type RNA - granulocytes [nTPM]":"22.9","Single Cell Type RNA - Granulosa cells [nTPM]":"14.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"12.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.8","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.5","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"14.4","Single Cell Type RNA - Langerhans cells [nTPM]":"28.5","Single Cell Type RNA - Late spermatids [nTPM]":"49.9","Single Cell Type RNA - Leydig cells [nTPM]":"22.1","Single Cell Type RNA - Macrophages [nTPM]":"13.1","Single Cell Type RNA - Melanocytes [nTPM]":"37.4","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"17.9","Single Cell Type RNA - Muller glia cells [nTPM]":"8.1","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"34.7","Single Cell Type RNA - Paneth cells [nTPM]":"4.9","Single Cell Type RNA - Peritubular cells [nTPM]":"16.1","Single Cell Type RNA - Plasma cells [nTPM]":"8.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"62.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"31.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.1","Single Cell Type RNA - Spermatocytes [nTPM]":"87.6","Single Cell Type RNA - Spermatogonia [nTPM]":"15.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"35.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"61.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"88.7","Single Cell Type RNA - T-cells [nTPM]":"19.4","Single Cell Type RNA - Theca cells [nTPM]":"26.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.1","Single Cell Type RNA - Urothelial cells [nTPM]":"59.9"},{"Gene":"TPI1","Gene synonym":[],"Ensembl":"ENSG00000111669","Gene description":"Triosephosphate isomerase 1","Uniprot":["P60174"],"Chromosome":"12","Position":"6867119-6870948","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Gluconeogenesis","Glycolysis"],"Molecular function":["Isomerase","Lyase"],"Disease involvement":["Cancer-related genes","Disease variant","Hereditary hemolytic anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"2470.8","tongue":"2005.8"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050924","HPA053568"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 16: Pancreatic endocrine cells - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA050924":"AB_2681276","HPA053568":"AB_2682193"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.04e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.54e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Tissue RNA - adipose tissue [nTPM]":"340.4","Tissue RNA - adrenal gland [nTPM]":"588.6","Tissue RNA - amygdala [nTPM]":"446.2","Tissue RNA - appendix [nTPM]":"269.7","Tissue RNA - basal ganglia [nTPM]":"480.2","Tissue RNA - bone marrow [nTPM]":"334.8","Tissue RNA - breast [nTPM]":"274.5","Tissue RNA - cerebellum [nTPM]":"476.5","Tissue RNA - cerebral cortex [nTPM]":"541.9","Tissue RNA - cervix [nTPM]":"314.1","Tissue RNA - choroid plexus [nTPM]":"446.9","Tissue RNA - colon [nTPM]":"425.6","Tissue RNA - duodenum [nTPM]":"421.0","Tissue RNA - endometrium 1 [nTPM]":"240.5","Tissue RNA - epididymis [nTPM]":"220.2","Tissue RNA - esophagus [nTPM]":"764.4","Tissue RNA - fallopian tube [nTPM]":"248.2","Tissue RNA - gallbladder [nTPM]":"216.8","Tissue RNA - heart muscle [nTPM]":"819.8","Tissue RNA - hippocampal formation [nTPM]":"481.0","Tissue RNA - hypothalamus [nTPM]":"462.0","Tissue RNA - kidney [nTPM]":"609.0","Tissue RNA - liver [nTPM]":"536.1","Tissue RNA - lung [nTPM]":"308.6","Tissue RNA - lymph node [nTPM]":"253.9","Tissue RNA - medulla oblongata [nTPM]":"459.2","Tissue RNA - midbrain [nTPM]":"460.4","Tissue RNA - ovary [nTPM]":"269.9","Tissue RNA - pancreas [nTPM]":"238.1","Tissue RNA - parathyroid gland [nTPM]":"496.4","Tissue RNA - pituitary gland [nTPM]":"236.8","Tissue RNA - placenta [nTPM]":"287.2","Tissue RNA - pons [nTPM]":"467.2","Tissue RNA - prostate [nTPM]":"272.1","Tissue RNA - rectum [nTPM]":"435.3","Tissue RNA - retina [nTPM]":"625.0","Tissue RNA - salivary gland [nTPM]":"377.6","Tissue RNA - seminal vesicle [nTPM]":"273.3","Tissue RNA - skeletal muscle [nTPM]":"2470.8","Tissue RNA - skin 1 [nTPM]":"410.1","Tissue RNA - small intestine [nTPM]":"404.5","Tissue RNA - smooth muscle [nTPM]":"301.5","Tissue RNA - spinal cord [nTPM]":"429.7","Tissue RNA - spleen [nTPM]":"291.4","Tissue RNA - stomach 1 [nTPM]":"329.0","Tissue RNA - testis [nTPM]":"239.8","Tissue RNA - thalamus [nTPM]":"503.5","Tissue RNA - thymus [nTPM]":"200.3","Tissue RNA - thyroid gland [nTPM]":"269.1","Tissue RNA - tongue [nTPM]":"2005.8","Tissue RNA - tonsil [nTPM]":"410.4","Tissue RNA - urinary bladder [nTPM]":"363.8","Tissue RNA - vagina [nTPM]":"440.6","Tissue RNA - white matter [nTPM]":"454.4","Cell RNA - A-431 [nTPM]":"1556.8","Cell RNA - A549 [nTPM]":"1350.5","Cell RNA - AF22 [nTPM]":"706.1","Cell RNA - AN3-CA [nTPM]":"1094.6","Cell RNA - ASC diff [nTPM]":"666.5","Cell RNA - ASC TERT1 [nTPM]":"696.6","Cell RNA - BEWO [nTPM]":"1236.3","Cell RNA - BJ [nTPM]":"1097.5","Cell RNA - BJ hTERT+ [nTPM]":"1184.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1999.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2407.5","Cell RNA - CACO-2 [nTPM]":"1409.9","Cell RNA - CAPAN-2 [nTPM]":"823.0","Cell RNA - Daudi [nTPM]":"903.4","Cell RNA - EFO-21 [nTPM]":"212.7","Cell RNA - fHDF\/TERT166 [nTPM]":"1069.7","Cell RNA - GAMG [nTPM]":"1042.4","Cell RNA - HaCaT [nTPM]":"748.8","Cell RNA - HAP1 [nTPM]":"1671.0","Cell RNA - HBEC3-KT [nTPM]":"1812.3","Cell RNA - HBF TERT88 [nTPM]":"2189.4","Cell RNA - HDLM-2 [nTPM]":"1196.4","Cell RNA - HEK 293 [nTPM]":"1265.1","Cell RNA - HEL [nTPM]":"1172.0","Cell RNA - HeLa [nTPM]":"924.4","Cell RNA - Hep G2 [nTPM]":"926.2","Cell RNA - HHSteC [nTPM]":"496.8","Cell RNA - HL-60 [nTPM]":"1351.5","Cell RNA - HMC-1 [nTPM]":"924.0","Cell RNA - HSkMC [nTPM]":"764.0","Cell RNA - hTCEpi [nTPM]":"739.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1537.8","Cell RNA - hTERT-HME1 [nTPM]":"1305.0","Cell RNA - hTERT-RPE1 [nTPM]":"2816.1","Cell RNA - HUVEC TERT2 [nTPM]":"1233.3","Cell RNA - JURKAT [nTPM]":"451.0","Cell RNA - K-562 [nTPM]":"615.0","Cell RNA - Karpas-707 [nTPM]":"336.5","Cell RNA - LHCN-M2 [nTPM]":"1554.5","Cell RNA - MCF7 [nTPM]":"1130.0","Cell RNA - MOLT-4 [nTPM]":"709.6","Cell RNA - NB-4 [nTPM]":"1119.5","Cell RNA - NTERA-2 [nTPM]":"1741.0","Cell RNA - OE19 [nTPM]":"1302.3","Cell RNA - PC-3 [nTPM]":"855.9","Cell RNA - REH [nTPM]":"413.5","Cell RNA - RH-30 [nTPM]":"1156.1","Cell RNA - RPMI-8226 [nTPM]":"930.7","Cell RNA - RPTEC TERT1 [nTPM]":"1261.4","Cell RNA - RT4 [nTPM]":"1061.1","Cell RNA - SCLC-21H [nTPM]":"497.2","Cell RNA - SH-SY5Y [nTPM]":"830.0","Cell RNA - SiHa [nTPM]":"953.3","Cell RNA - SK-BR-3 [nTPM]":"977.8","Cell RNA - SK-MEL-30 [nTPM]":"542.7","Cell RNA - SuSa [nTPM]":"1452.6","Cell RNA - T-47d [nTPM]":"224.4","Cell RNA - THP-1 [nTPM]":"1003.2","Cell RNA - TIME [nTPM]":"778.2","Cell RNA - U-138 MG [nTPM]":"1068.0","Cell RNA - U-2 OS [nTPM]":"914.6","Cell RNA - U-2197 [nTPM]":"703.1","Cell RNA - U-251 MG [nTPM]":"1631.7","Cell RNA - U-266\/70 [nTPM]":"653.4","Cell RNA - U-266\/84 [nTPM]":"285.7","Cell RNA - U-698 [nTPM]":"1327.8","Cell RNA - U-87 MG [nTPM]":"2153.1","Cell RNA - U-937 [nTPM]":"821.2","Cell RNA - WM-115 [nTPM]":"784.9","Blood RNA - basophil [nTPM]":"1708.8","Blood RNA - classical monocyte [nTPM]":"2304.1","Blood RNA - eosinophil [nTPM]":"2375.2","Blood RNA - gdT-cell [nTPM]":"824.6","Blood RNA - intermediate monocyte [nTPM]":"2402.3","Blood RNA - MAIT T-cell [nTPM]":"845.7","Blood RNA - memory B-cell [nTPM]":"863.3","Blood RNA - memory CD4 T-cell [nTPM]":"820.0","Blood RNA - memory CD8 T-cell [nTPM]":"808.0","Blood RNA - myeloid DC [nTPM]":"2656.1","Blood RNA - naive B-cell [nTPM]":"800.9","Blood RNA - naive CD4 T-cell [nTPM]":"570.5","Blood RNA - naive CD8 T-cell [nTPM]":"703.0","Blood RNA - neutrophil [nTPM]":"934.3","Blood RNA - NK-cell [nTPM]":"1387.7","Blood RNA - non-classical monocyte [nTPM]":"2165.7","Blood RNA - plasmacytoid DC [nTPM]":"482.0","Blood RNA - T-reg [nTPM]":"1106.3","Blood RNA - total PBMC [nTPM]":"4679.5","Brain RNA - amygdala [nTPM]":"446.2","Brain RNA - basal ganglia [nTPM]":"480.2","Brain RNA - cerebellum [nTPM]":"476.5","Brain RNA - cerebral cortex [nTPM]":"541.9","Brain RNA - hippocampal formation [nTPM]":"481.0","Brain RNA - hypothalamus [nTPM]":"462.0","Brain RNA - medulla oblongata [nTPM]":"459.2","Brain RNA - midbrain [nTPM]":"460.4","Brain RNA - pons [nTPM]":"467.2","Brain RNA - spinal cord [nTPM]":"429.7","Brain RNA - thalamus [nTPM]":"503.5","Brain RNA - white matter [nTPM]":"454.4","Single Cell Type RNA - Adipocytes [nTPM]":"311.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"134.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"204.2","Single Cell Type RNA - Astrocytes [nTPM]":"34.6","Single Cell Type RNA - B-cells [nTPM]":"290.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"684.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"553.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1756.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"414.9","Single Cell Type RNA - Bipolar cells [nTPM]":"284.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"294.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"303.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"552.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"391.7","Single Cell Type RNA - Club cells [nTPM]":"673.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"389.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"110.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1017.0","Single Cell Type RNA - dendritic cells [nTPM]":"278.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"850.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1508.5","Single Cell Type RNA - Ductal cells [nTPM]":"1361.5","Single Cell Type RNA - Early spermatids [nTPM]":"203.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"280.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"307.0","Single Cell Type RNA - Endothelial cells [nTPM]":"352.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"425.5","Single Cell Type RNA - Erythroid cells [nTPM]":"243.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"38.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"786.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1824.0","Single Cell Type RNA - Fibroblasts [nTPM]":"386.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"408.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"343.9","Single Cell Type RNA - granulocytes [nTPM]":"362.8","Single Cell Type RNA - Granulosa cells [nTPM]":"364.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"276.6","Single Cell Type RNA - Hepatocytes [nTPM]":"547.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"937.3","Single Cell Type RNA - Horizontal cells [nTPM]":"297.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"33.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"567.2","Single Cell Type RNA - Ionocytes [nTPM]":"1151.5","Single Cell Type RNA - Kupffer cells [nTPM]":"386.7","Single Cell Type RNA - Langerhans cells [nTPM]":"750.4","Single Cell Type RNA - Late spermatids [nTPM]":"683.5","Single Cell Type RNA - Leydig cells [nTPM]":"279.0","Single Cell Type RNA - Macrophages [nTPM]":"482.8","Single Cell Type RNA - Melanocytes [nTPM]":"674.1","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"1129.8","Single Cell Type RNA - Muller glia cells [nTPM]":"739.6","Single Cell Type RNA - NK-cells [nTPM]":"312.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"26.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1081.5","Single Cell Type RNA - Paneth cells [nTPM]":"889.4","Single Cell Type RNA - Peritubular cells [nTPM]":"263.3","Single Cell Type RNA - Plasma cells [nTPM]":"427.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"556.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1595.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1642.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"401.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"298.0","Single Cell Type RNA - Sertoli cells [nTPM]":"197.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"270.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"551.3","Single Cell Type RNA - Spermatocytes [nTPM]":"14.9","Single Cell Type RNA - Spermatogonia [nTPM]":"79.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"690.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"615.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1530.4","Single Cell Type RNA - T-cells [nTPM]":"352.9","Single Cell Type RNA - Theca cells [nTPM]":"869.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"827.0","Single Cell Type RNA - Urothelial cells [nTPM]":"652.5"},{"Gene":"TPP1","Gene synonym":["CLN2","LPIC","SCAR7","TPP-1"],"Ensembl":"ENSG00000166340","Gene description":"Tripeptidyl peptidase 1","Uniprot":["O14773"],"Chromosome":"11","Position":"6612768-6619448","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration","Neuronal ceroid lipofuscinosis","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"261.6","Kupffer cells":"376.5","Macrophages":"219.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037709","HPA044868"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9500000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA037709":"AB_10672913","HPA044868":"AB_2679122"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.27e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.31e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.11e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.46e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Tissue RNA - adipose tissue [nTPM]":"74.7","Tissue RNA - adrenal gland [nTPM]":"145.9","Tissue RNA - amygdala [nTPM]":"71.0","Tissue RNA - appendix [nTPM]":"74.6","Tissue RNA - basal ganglia [nTPM]":"81.0","Tissue RNA - bone marrow [nTPM]":"111.7","Tissue RNA - breast [nTPM]":"44.3","Tissue RNA - cerebellum [nTPM]":"80.3","Tissue RNA - cerebral cortex [nTPM]":"81.4","Tissue RNA - cervix [nTPM]":"53.8","Tissue RNA - choroid plexus [nTPM]":"120.1","Tissue RNA - colon [nTPM]":"59.1","Tissue RNA - duodenum [nTPM]":"59.9","Tissue RNA - endometrium 1 [nTPM]":"74.0","Tissue RNA - epididymis [nTPM]":"43.1","Tissue RNA - esophagus [nTPM]":"39.5","Tissue RNA - fallopian tube [nTPM]":"47.1","Tissue RNA - gallbladder [nTPM]":"65.1","Tissue RNA - heart muscle [nTPM]":"56.3","Tissue RNA - hippocampal formation [nTPM]":"70.6","Tissue RNA - hypothalamus [nTPM]":"78.4","Tissue RNA - kidney [nTPM]":"71.6","Tissue RNA - liver [nTPM]":"92.7","Tissue RNA - lung [nTPM]":"81.5","Tissue RNA - lymph node [nTPM]":"77.7","Tissue RNA - medulla oblongata [nTPM]":"85.2","Tissue RNA - midbrain [nTPM]":"82.6","Tissue RNA - ovary [nTPM]":"49.7","Tissue RNA - pancreas [nTPM]":"36.2","Tissue RNA - parathyroid gland [nTPM]":"54.2","Tissue RNA - pituitary gland [nTPM]":"63.6","Tissue RNA - placenta [nTPM]":"94.2","Tissue RNA - pons [nTPM]":"81.0","Tissue RNA - prostate [nTPM]":"38.9","Tissue RNA - rectum [nTPM]":"59.7","Tissue RNA - retina [nTPM]":"48.5","Tissue RNA - salivary gland [nTPM]":"42.5","Tissue RNA - seminal vesicle [nTPM]":"57.5","Tissue RNA - skeletal muscle [nTPM]":"31.4","Tissue RNA - skin 1 [nTPM]":"39.5","Tissue RNA - small intestine [nTPM]":"73.3","Tissue RNA - smooth muscle [nTPM]":"92.0","Tissue RNA - spinal cord [nTPM]":"74.7","Tissue RNA - spleen [nTPM]":"135.0","Tissue RNA - stomach 1 [nTPM]":"48.4","Tissue RNA - testis [nTPM]":"20.0","Tissue RNA - thalamus [nTPM]":"83.3","Tissue RNA - thymus [nTPM]":"47.4","Tissue RNA - thyroid gland [nTPM]":"45.7","Tissue RNA - tongue [nTPM]":"39.0","Tissue RNA - tonsil [nTPM]":"60.9","Tissue RNA - urinary bladder [nTPM]":"68.4","Tissue RNA - vagina [nTPM]":"42.8","Tissue RNA - white matter [nTPM]":"90.4","Cell RNA - A-431 [nTPM]":"26.1","Cell RNA - A549 [nTPM]":"48.1","Cell RNA - AF22 [nTPM]":"25.9","Cell RNA - AN3-CA [nTPM]":"50.5","Cell RNA - ASC diff [nTPM]":"309.9","Cell RNA - ASC TERT1 [nTPM]":"160.1","Cell RNA - BEWO [nTPM]":"21.8","Cell RNA - BJ [nTPM]":"50.9","Cell RNA - BJ hTERT+ [nTPM]":"220.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"36.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"62.0","Cell RNA - CACO-2 [nTPM]":"20.1","Cell RNA - CAPAN-2 [nTPM]":"122.5","Cell RNA - Daudi [nTPM]":"37.4","Cell RNA - EFO-21 [nTPM]":"32.6","Cell RNA - fHDF\/TERT166 [nTPM]":"136.6","Cell RNA - GAMG [nTPM]":"220.2","Cell RNA - HaCaT [nTPM]":"85.8","Cell RNA - HAP1 [nTPM]":"48.3","Cell RNA - HBEC3-KT [nTPM]":"68.7","Cell RNA - HBF TERT88 [nTPM]":"57.9","Cell RNA - HDLM-2 [nTPM]":"37.3","Cell RNA - HEK 293 [nTPM]":"27.6","Cell RNA - HEL [nTPM]":"32.2","Cell RNA - HeLa [nTPM]":"23.8","Cell RNA - Hep G2 [nTPM]":"54.9","Cell RNA - HHSteC [nTPM]":"210.9","Cell RNA - HL-60 [nTPM]":"45.8","Cell RNA - HMC-1 [nTPM]":"182.6","Cell RNA - HSkMC [nTPM]":"231.8","Cell RNA - hTCEpi [nTPM]":"104.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"45.9","Cell RNA - hTERT-HME1 [nTPM]":"102.6","Cell RNA - hTERT-RPE1 [nTPM]":"240.4","Cell RNA - HUVEC TERT2 [nTPM]":"158.8","Cell RNA - JURKAT [nTPM]":"32.9","Cell RNA - K-562 [nTPM]":"59.8","Cell RNA - Karpas-707 [nTPM]":"124.6","Cell RNA - LHCN-M2 [nTPM]":"110.4","Cell RNA - MCF7 [nTPM]":"30.2","Cell RNA - MOLT-4 [nTPM]":"16.6","Cell RNA - NB-4 [nTPM]":"52.4","Cell RNA - NTERA-2 [nTPM]":"18.0","Cell RNA - OE19 [nTPM]":"61.5","Cell RNA - PC-3 [nTPM]":"57.1","Cell RNA - REH [nTPM]":"36.1","Cell RNA - RH-30 [nTPM]":"21.6","Cell RNA - RPMI-8226 [nTPM]":"77.0","Cell RNA - RPTEC TERT1 [nTPM]":"62.8","Cell RNA - RT4 [nTPM]":"38.2","Cell RNA - SCLC-21H [nTPM]":"4.5","Cell RNA - SH-SY5Y [nTPM]":"20.4","Cell RNA - SiHa [nTPM]":"52.6","Cell RNA - SK-BR-3 [nTPM]":"44.6","Cell RNA - SK-MEL-30 [nTPM]":"91.0","Cell RNA - SuSa [nTPM]":"76.5","Cell RNA - T-47d [nTPM]":"30.8","Cell RNA - THP-1 [nTPM]":"79.7","Cell RNA - TIME [nTPM]":"188.0","Cell RNA - U-138 MG [nTPM]":"119.7","Cell RNA - U-2 OS [nTPM]":"33.1","Cell RNA - U-2197 [nTPM]":"101.1","Cell RNA - U-251 MG [nTPM]":"19.8","Cell RNA - U-266\/70 [nTPM]":"92.3","Cell RNA - U-266\/84 [nTPM]":"95.3","Cell RNA - U-698 [nTPM]":"14.0","Cell RNA - U-87 MG [nTPM]":"139.8","Cell RNA - U-937 [nTPM]":"101.7","Cell RNA - WM-115 [nTPM]":"64.5","Blood RNA - basophil [nTPM]":"67.0","Blood RNA - classical monocyte [nTPM]":"167.1","Blood RNA - eosinophil [nTPM]":"38.2","Blood RNA - gdT-cell [nTPM]":"39.9","Blood RNA - intermediate monocyte [nTPM]":"171.2","Blood RNA - MAIT T-cell [nTPM]":"30.0","Blood RNA - memory B-cell [nTPM]":"35.1","Blood RNA - memory CD4 T-cell [nTPM]":"31.4","Blood RNA - memory CD8 T-cell [nTPM]":"41.0","Blood RNA - myeloid DC [nTPM]":"185.9","Blood RNA - naive B-cell [nTPM]":"37.0","Blood RNA - naive CD4 T-cell [nTPM]":"20.1","Blood RNA - naive CD8 T-cell [nTPM]":"27.2","Blood RNA - neutrophil [nTPM]":"27.5","Blood RNA - NK-cell [nTPM]":"29.1","Blood RNA - non-classical monocyte [nTPM]":"125.1","Blood RNA - plasmacytoid DC [nTPM]":"93.1","Blood RNA - T-reg [nTPM]":"60.3","Blood RNA - total PBMC [nTPM]":"138.8","Brain RNA - amygdala [nTPM]":"71.0","Brain RNA - basal ganglia [nTPM]":"81.0","Brain RNA - cerebellum [nTPM]":"80.3","Brain RNA - cerebral cortex [nTPM]":"81.4","Brain RNA - hippocampal formation [nTPM]":"70.6","Brain RNA - hypothalamus [nTPM]":"78.4","Brain RNA - medulla oblongata [nTPM]":"85.2","Brain RNA - midbrain [nTPM]":"82.6","Brain RNA - pons [nTPM]":"81.0","Brain RNA - spinal cord [nTPM]":"74.7","Brain RNA - thalamus [nTPM]":"83.3","Brain RNA - white matter [nTPM]":"90.4","Single Cell Type RNA - Adipocytes [nTPM]":"32.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"37.3","Single Cell Type RNA - Astrocytes [nTPM]":"31.6","Single Cell Type RNA - B-cells [nTPM]":"53.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"23.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"28.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Bipolar cells [nTPM]":"24.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"41.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"50.1","Single Cell Type RNA - Club cells [nTPM]":"26.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"35.4","Single Cell Type RNA - dendritic cells [nTPM]":"71.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"55.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"42.2","Single Cell Type RNA - Early spermatids [nTPM]":"11.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"30.2","Single Cell Type RNA - Endothelial cells [nTPM]":"40.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.7","Single Cell Type RNA - Erythroid cells [nTPM]":"37.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"45.3","Single Cell Type RNA - Fibroblasts [nTPM]":"40.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.8","Single Cell Type RNA - granulocytes [nTPM]":"62.2","Single Cell Type RNA - Granulosa cells [nTPM]":"25.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"75.7","Single Cell Type RNA - Hepatocytes [nTPM]":"81.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"261.6","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.3","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"376.5","Single Cell Type RNA - Langerhans cells [nTPM]":"126.5","Single Cell Type RNA - Late spermatids [nTPM]":"11.2","Single Cell Type RNA - Leydig cells [nTPM]":"27.1","Single Cell Type RNA - Macrophages [nTPM]":"219.8","Single Cell Type RNA - Melanocytes [nTPM]":"90.7","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"156.0","Single Cell Type RNA - Muller glia cells [nTPM]":"37.9","Single Cell Type RNA - NK-cells [nTPM]":"49.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.4","Single Cell Type RNA - Paneth cells [nTPM]":"44.1","Single Cell Type RNA - Peritubular cells [nTPM]":"26.4","Single Cell Type RNA - Plasma cells [nTPM]":"26.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"99.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"51.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"1.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"27.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"88.0","Single Cell Type RNA - T-cells [nTPM]":"42.2","Single Cell Type RNA - Theca cells [nTPM]":"24.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"32.5","Single Cell Type RNA - Urothelial cells [nTPM]":"26.5"},{"Gene":"TPR","Gene synonym":[],"Ensembl":"ENSG00000047410","Gene description":"Translocated promoter region, nuclear basket protein","Uniprot":["P12270"],"Chromosome":"1","Position":"186311652-186375693","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Cell cycle","Cell division","Mitosis","mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"772.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019661","HPA019663","HPA024336"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"30000000","Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA019661":"AB_1858215","HPA019663":"AB_1858216","HPA024336":"AB_1858217"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.87e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.88e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.71e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.06e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Tissue RNA - adipose tissue [nTPM]":"19.8","Tissue RNA - adrenal gland [nTPM]":"14.5","Tissue RNA - amygdala [nTPM]":"12.2","Tissue RNA - appendix [nTPM]":"23.4","Tissue RNA - basal ganglia [nTPM]":"14.1","Tissue RNA - bone marrow [nTPM]":"28.9","Tissue RNA - breast [nTPM]":"19.7","Tissue RNA - cerebellum [nTPM]":"14.4","Tissue RNA - cerebral cortex [nTPM]":"10.9","Tissue RNA - cervix [nTPM]":"17.6","Tissue RNA - choroid plexus [nTPM]":"18.4","Tissue RNA - colon [nTPM]":"17.6","Tissue RNA - duodenum [nTPM]":"15.5","Tissue RNA - endometrium 1 [nTPM]":"20.3","Tissue RNA - epididymis [nTPM]":"19.7","Tissue RNA - esophagus [nTPM]":"14.8","Tissue RNA - fallopian tube [nTPM]":"15.0","Tissue RNA - gallbladder [nTPM]":"16.1","Tissue RNA - heart muscle [nTPM]":"17.1","Tissue RNA - hippocampal formation [nTPM]":"9.5","Tissue RNA - hypothalamus [nTPM]":"12.9","Tissue RNA - kidney [nTPM]":"16.0","Tissue RNA - liver [nTPM]":"15.4","Tissue RNA - lung [nTPM]":"18.0","Tissue RNA - lymph node [nTPM]":"26.0","Tissue RNA - medulla oblongata [nTPM]":"13.6","Tissue RNA - midbrain [nTPM]":"12.0","Tissue RNA - ovary [nTPM]":"23.1","Tissue RNA - pancreas [nTPM]":"15.5","Tissue RNA - parathyroid gland [nTPM]":"34.2","Tissue RNA - pituitary gland [nTPM]":"13.4","Tissue RNA - placenta [nTPM]":"26.7","Tissue RNA - pons [nTPM]":"13.8","Tissue RNA - prostate [nTPM]":"17.2","Tissue RNA - rectum [nTPM]":"20.0","Tissue RNA - retina [nTPM]":"19.8","Tissue RNA - salivary gland [nTPM]":"15.8","Tissue RNA - seminal vesicle [nTPM]":"17.6","Tissue RNA - skeletal muscle [nTPM]":"20.4","Tissue RNA - skin 1 [nTPM]":"24.2","Tissue RNA - small intestine [nTPM]":"19.3","Tissue RNA - smooth muscle [nTPM]":"17.6","Tissue RNA - spinal cord [nTPM]":"12.2","Tissue RNA - spleen [nTPM]":"22.9","Tissue RNA - stomach 1 [nTPM]":"19.1","Tissue RNA - testis [nTPM]":"43.8","Tissue RNA - thalamus [nTPM]":"13.3","Tissue RNA - thymus [nTPM]":"31.0","Tissue RNA - thyroid gland [nTPM]":"22.7","Tissue RNA - tongue [nTPM]":"22.3","Tissue RNA - tonsil [nTPM]":"26.0","Tissue RNA - urinary bladder [nTPM]":"19.6","Tissue RNA - vagina [nTPM]":"14.5","Tissue RNA - white matter [nTPM]":"15.1","Cell RNA - A-431 [nTPM]":"55.9","Cell RNA - A549 [nTPM]":"46.7","Cell RNA - AF22 [nTPM]":"68.2","Cell RNA - AN3-CA [nTPM]":"39.8","Cell RNA - ASC diff [nTPM]":"53.4","Cell RNA - ASC TERT1 [nTPM]":"47.4","Cell RNA - BEWO [nTPM]":"73.2","Cell RNA - BJ [nTPM]":"62.0","Cell RNA - BJ hTERT+ [nTPM]":"41.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"42.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"40.4","Cell RNA - CACO-2 [nTPM]":"70.5","Cell RNA - CAPAN-2 [nTPM]":"45.9","Cell RNA - Daudi [nTPM]":"64.0","Cell RNA - EFO-21 [nTPM]":"47.1","Cell RNA - fHDF\/TERT166 [nTPM]":"42.1","Cell RNA - GAMG [nTPM]":"29.4","Cell RNA - HaCaT [nTPM]":"70.9","Cell RNA - HAP1 [nTPM]":"51.9","Cell RNA - HBEC3-KT [nTPM]":"42.4","Cell RNA - HBF TERT88 [nTPM]":"52.1","Cell RNA - HDLM-2 [nTPM]":"51.8","Cell RNA - HEK 293 [nTPM]":"58.6","Cell RNA - HEL [nTPM]":"86.8","Cell RNA - HeLa [nTPM]":"78.3","Cell RNA - Hep G2 [nTPM]":"49.7","Cell RNA - HHSteC [nTPM]":"28.7","Cell RNA - HL-60 [nTPM]":"93.1","Cell RNA - HMC-1 [nTPM]":"53.5","Cell RNA - HSkMC [nTPM]":"36.4","Cell RNA - hTCEpi [nTPM]":"25.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"64.4","Cell RNA - hTERT-HME1 [nTPM]":"49.4","Cell RNA - hTERT-RPE1 [nTPM]":"39.3","Cell RNA - HUVEC TERT2 [nTPM]":"51.3","Cell RNA - JURKAT [nTPM]":"36.5","Cell RNA - K-562 [nTPM]":"106.0","Cell RNA - Karpas-707 [nTPM]":"57.3","Cell RNA - LHCN-M2 [nTPM]":"45.8","Cell RNA - MCF7 [nTPM]":"47.5","Cell RNA - MOLT-4 [nTPM]":"46.2","Cell RNA - NB-4 [nTPM]":"24.5","Cell RNA - NTERA-2 [nTPM]":"76.1","Cell RNA - OE19 [nTPM]":"49.9","Cell RNA - PC-3 [nTPM]":"16.0","Cell RNA - REH [nTPM]":"54.3","Cell RNA - RH-30 [nTPM]":"54.3","Cell RNA - RPMI-8226 [nTPM]":"56.5","Cell RNA - RPTEC TERT1 [nTPM]":"34.8","Cell RNA - RT4 [nTPM]":"65.0","Cell RNA - SCLC-21H [nTPM]":"37.7","Cell RNA - SH-SY5Y [nTPM]":"59.5","Cell RNA - SiHa [nTPM]":"72.9","Cell RNA - SK-BR-3 [nTPM]":"47.1","Cell RNA - SK-MEL-30 [nTPM]":"37.6","Cell RNA - SuSa [nTPM]":"92.5","Cell RNA - T-47d [nTPM]":"53.1","Cell RNA - THP-1 [nTPM]":"58.0","Cell RNA - TIME [nTPM]":"73.0","Cell RNA - U-138 MG [nTPM]":"42.5","Cell RNA - U-2 OS [nTPM]":"40.6","Cell RNA - U-2197 [nTPM]":"47.7","Cell RNA - U-251 MG [nTPM]":"76.6","Cell RNA - U-266\/70 [nTPM]":"63.2","Cell RNA - U-266\/84 [nTPM]":"77.6","Cell RNA - U-698 [nTPM]":"57.0","Cell RNA - U-87 MG [nTPM]":"27.5","Cell RNA - U-937 [nTPM]":"45.8","Cell RNA - WM-115 [nTPM]":"38.7","Blood RNA - basophil [nTPM]":"121.4","Blood RNA - classical monocyte [nTPM]":"34.1","Blood RNA - eosinophil [nTPM]":"69.0","Blood RNA - gdT-cell [nTPM]":"43.8","Blood RNA - intermediate monocyte [nTPM]":"30.0","Blood RNA - MAIT T-cell [nTPM]":"37.7","Blood RNA - memory B-cell [nTPM]":"48.9","Blood RNA - memory CD4 T-cell [nTPM]":"38.6","Blood RNA - memory CD8 T-cell [nTPM]":"36.8","Blood RNA - myeloid DC [nTPM]":"20.6","Blood RNA - naive B-cell [nTPM]":"55.4","Blood RNA - naive CD4 T-cell [nTPM]":"47.3","Blood RNA - naive CD8 T-cell [nTPM]":"32.8","Blood RNA - neutrophil [nTPM]":"145.7","Blood RNA - NK-cell [nTPM]":"33.0","Blood RNA - non-classical monocyte [nTPM]":"50.4","Blood RNA - plasmacytoid DC [nTPM]":"58.7","Blood RNA - T-reg [nTPM]":"49.1","Blood RNA - total PBMC [nTPM]":"17.3","Brain RNA - amygdala [nTPM]":"12.2","Brain RNA - basal ganglia [nTPM]":"14.1","Brain RNA - cerebellum [nTPM]":"14.4","Brain RNA - cerebral cortex [nTPM]":"10.9","Brain RNA - hippocampal formation [nTPM]":"9.5","Brain RNA - hypothalamus [nTPM]":"12.9","Brain RNA - medulla oblongata [nTPM]":"13.6","Brain RNA - midbrain [nTPM]":"12.0","Brain RNA - pons [nTPM]":"13.8","Brain RNA - spinal cord [nTPM]":"12.2","Brain RNA - thalamus [nTPM]":"13.3","Brain RNA - white matter [nTPM]":"15.1","Single Cell Type RNA - Adipocytes [nTPM]":"126.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"218.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"119.6","Single Cell Type RNA - Astrocytes [nTPM]":"43.1","Single Cell Type RNA - B-cells [nTPM]":"122.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"101.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"105.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"98.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"114.9","Single Cell Type RNA - Bipolar cells [nTPM]":"89.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"65.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"79.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"180.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"54.3","Single Cell Type RNA - Club cells [nTPM]":"110.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"58.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"79.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"136.9","Single Cell Type RNA - dendritic cells [nTPM]":"136.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"51.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"107.1","Single Cell Type RNA - Early spermatids [nTPM]":"199.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"129.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"151.7","Single Cell Type RNA - Endothelial cells [nTPM]":"123.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"67.7","Single Cell Type RNA - Erythroid cells [nTPM]":"102.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"42.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"74.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"99.9","Single Cell Type RNA - Fibroblasts [nTPM]":"126.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"80.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"134.4","Single Cell Type RNA - granulocytes [nTPM]":"81.0","Single Cell Type RNA - Granulosa cells [nTPM]":"134.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"74.6","Single Cell Type RNA - Hepatocytes [nTPM]":"40.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"72.8","Single Cell Type RNA - Horizontal cells [nTPM]":"99.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"42.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"61.9","Single Cell Type RNA - Ionocytes [nTPM]":"93.6","Single Cell Type RNA - Kupffer cells [nTPM]":"64.2","Single Cell Type RNA - Langerhans cells [nTPM]":"79.3","Single Cell Type RNA - Late spermatids [nTPM]":"50.4","Single Cell Type RNA - Leydig cells [nTPM]":"125.6","Single Cell Type RNA - Macrophages [nTPM]":"92.6","Single Cell Type RNA - Melanocytes [nTPM]":"55.2","Single Cell Type RNA - Microglial cells [nTPM]":"39.4","Single Cell Type RNA - monocytes [nTPM]":"137.3","Single Cell Type RNA - Muller glia cells [nTPM]":"101.1","Single Cell Type RNA - NK-cells [nTPM]":"139.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"48.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"62.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"90.1","Single Cell Type RNA - Paneth cells [nTPM]":"56.7","Single Cell Type RNA - Peritubular cells [nTPM]":"117.4","Single Cell Type RNA - Plasma cells [nTPM]":"113.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"95.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"52.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"27.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"120.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"111.4","Single Cell Type RNA - Sertoli cells [nTPM]":"131.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"172.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"152.1","Single Cell Type RNA - Spermatocytes [nTPM]":"772.9","Single Cell Type RNA - Spermatogonia [nTPM]":"250.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"85.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"99.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"150.8","Single Cell Type RNA - T-cells [nTPM]":"145.8","Single Cell Type RNA - Theca cells [nTPM]":"160.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"77.7","Single Cell Type RNA - Urothelial cells [nTPM]":"96.0"},{"Gene":"TPSAB1","Gene synonym":["TPS1","TPS2","TPSB1"],"Ensembl":"ENSG00000172236","Gene description":"Tryptase alpha\/beta 1","Uniprot":["Q15661"],"Chromosome":"16","Position":"1240379-1242554","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"granulocytes":"5873.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"893","RNA blood cell specific nTPM":{"basophil":"89.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"893","RNA blood lineage specific nTPM":{"granulocytes":"89.3"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"166","RNA cell line specific nTPM":{"HMC-1":"3813.2"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016369","CAB022175","HPA049153","HPA049554"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 60: Granulocytes - Receptor signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB016369":"AB_628406","CAB022175":null,"HPA049153":"AB_2680656","HPA049554":"AB_2680815"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.31e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.62e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Tissue RNA - adipose tissue [nTPM]":"96.6","Tissue RNA - adrenal gland [nTPM]":"2.9","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"23.6","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"2.4","Tissue RNA - breast [nTPM]":"47.2","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"0.9","Tissue RNA - cervix [nTPM]":"53.7","Tissue RNA - choroid plexus [nTPM]":"0.9","Tissue RNA - colon [nTPM]":"83.0","Tissue RNA - duodenum [nTPM]":"71.6","Tissue RNA - endometrium 1 [nTPM]":"73.3","Tissue RNA - epididymis [nTPM]":"6.0","Tissue RNA - esophagus [nTPM]":"64.3","Tissue RNA - fallopian tube [nTPM]":"26.6","Tissue RNA - gallbladder [nTPM]":"129.7","Tissue RNA - heart muscle [nTPM]":"14.7","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"0.4","Tissue RNA - kidney [nTPM]":"13.9","Tissue RNA - liver [nTPM]":"12.2","Tissue RNA - lung [nTPM]":"128.5","Tissue RNA - lymph node [nTPM]":"21.3","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"3.2","Tissue RNA - pancreas [nTPM]":"18.9","Tissue RNA - parathyroid gland [nTPM]":"2.3","Tissue RNA - pituitary gland [nTPM]":"3.5","Tissue RNA - placenta [nTPM]":"1.2","Tissue RNA - pons [nTPM]":"0.6","Tissue RNA - prostate [nTPM]":"65.9","Tissue RNA - rectum [nTPM]":"34.6","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"60.2","Tissue RNA - seminal vesicle [nTPM]":"22.5","Tissue RNA - skeletal muscle [nTPM]":"10.1","Tissue RNA - skin 1 [nTPM]":"122.7","Tissue RNA - small intestine [nTPM]":"148.7","Tissue RNA - smooth muscle [nTPM]":"17.9","Tissue RNA - spinal cord [nTPM]":"0.4","Tissue RNA - spleen [nTPM]":"5.9","Tissue RNA - stomach 1 [nTPM]":"104.0","Tissue RNA - testis [nTPM]":"8.9","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"14.2","Tissue RNA - thyroid gland [nTPM]":"4.7","Tissue RNA - tongue [nTPM]":"13.0","Tissue RNA - tonsil [nTPM]":"13.2","Tissue RNA - urinary bladder [nTPM]":"113.5","Tissue RNA - vagina [nTPM]":"52.6","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"2.7","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"19.3","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"1.3","Cell RNA - HMC-1 [nTPM]":"3813.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"7.7","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"2.1","Cell RNA - NB-4 [nTPM]":"6.1","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.4","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.4","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"1.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"2.8","Cell RNA - U-937 [nTPM]":"22.9","Cell RNA - WM-115 [nTPM]":"2.0","Blood RNA - basophil [nTPM]":"89.3","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.7","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"0.9","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"0.4","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.6","Brain RNA - spinal cord [nTPM]":"0.4","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"135.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"8.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"4.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"7.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"5873.9","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"25.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"7.7","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"2.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"11.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"440.9","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.5","Single Cell Type RNA - Urothelial cells [nTPM]":"5.6"},{"Gene":"TRAF3","Gene synonym":["CAP-1","CD40bp","CRAF1","LAP1","RNF118"],"Ensembl":"ENSG00000131323","Gene description":"TNF receptor associated factor 3","Uniprot":["Q13114"],"Chromosome":"14","Position":"102777449-102911500","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Immunity","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"108.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002933"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA002933":"AB_1080352"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.02e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.42e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.6","Tissue RNA - adrenal gland [nTPM]":"4.2","Tissue RNA - amygdala [nTPM]":"8.3","Tissue RNA - appendix [nTPM]":"18.8","Tissue RNA - basal ganglia [nTPM]":"8.7","Tissue RNA - bone marrow [nTPM]":"20.5","Tissue RNA - breast [nTPM]":"4.8","Tissue RNA - cerebellum [nTPM]":"6.3","Tissue RNA - cerebral cortex [nTPM]":"14.5","Tissue RNA - cervix [nTPM]":"3.9","Tissue RNA - choroid plexus [nTPM]":"7.6","Tissue RNA - colon [nTPM]":"7.9","Tissue RNA - duodenum [nTPM]":"7.7","Tissue RNA - endometrium 1 [nTPM]":"5.8","Tissue RNA - epididymis [nTPM]":"2.3","Tissue RNA - esophagus [nTPM]":"6.6","Tissue RNA - fallopian tube [nTPM]":"6.8","Tissue RNA - gallbladder [nTPM]":"6.2","Tissue RNA - heart muscle [nTPM]":"6.3","Tissue RNA - hippocampal formation [nTPM]":"15.6","Tissue RNA - hypothalamus [nTPM]":"12.1","Tissue RNA - kidney [nTPM]":"5.4","Tissue RNA - liver [nTPM]":"6.4","Tissue RNA - lung [nTPM]":"7.3","Tissue RNA - lymph node [nTPM]":"20.9","Tissue RNA - medulla oblongata [nTPM]":"9.8","Tissue RNA - midbrain [nTPM]":"9.9","Tissue RNA - ovary [nTPM]":"3.3","Tissue RNA - pancreas [nTPM]":"4.5","Tissue RNA - parathyroid gland [nTPM]":"7.2","Tissue RNA - pituitary gland [nTPM]":"8.4","Tissue RNA - placenta [nTPM]":"3.9","Tissue RNA - pons [nTPM]":"9.5","Tissue RNA - prostate [nTPM]":"5.0","Tissue RNA - rectum [nTPM]":"6.3","Tissue RNA - retina [nTPM]":"4.4","Tissue RNA - salivary gland [nTPM]":"4.8","Tissue RNA - seminal vesicle [nTPM]":"5.7","Tissue RNA - skeletal muscle [nTPM]":"5.6","Tissue RNA - skin 1 [nTPM]":"6.8","Tissue RNA - small intestine [nTPM]":"10.7","Tissue RNA - smooth muscle [nTPM]":"6.4","Tissue RNA - spinal cord [nTPM]":"8.1","Tissue RNA - spleen [nTPM]":"12.0","Tissue RNA - stomach 1 [nTPM]":"6.7","Tissue RNA - testis [nTPM]":"10.7","Tissue RNA - thalamus [nTPM]":"12.8","Tissue RNA - thymus [nTPM]":"9.4","Tissue RNA - thyroid gland [nTPM]":"6.1","Tissue RNA - tongue [nTPM]":"3.3","Tissue RNA - tonsil [nTPM]":"15.9","Tissue RNA - urinary bladder [nTPM]":"8.8","Tissue RNA - vagina [nTPM]":"4.7","Tissue RNA - white matter [nTPM]":"8.0","Cell RNA - A-431 [nTPM]":"25.3","Cell RNA - A549 [nTPM]":"26.4","Cell RNA - AF22 [nTPM]":"14.8","Cell RNA - AN3-CA [nTPM]":"9.7","Cell RNA - ASC diff [nTPM]":"7.5","Cell RNA - ASC TERT1 [nTPM]":"11.4","Cell RNA - BEWO [nTPM]":"23.4","Cell RNA - BJ [nTPM]":"19.1","Cell RNA - BJ hTERT+ [nTPM]":"19.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.7","Cell RNA - CACO-2 [nTPM]":"13.3","Cell RNA - CAPAN-2 [nTPM]":"36.7","Cell RNA - Daudi [nTPM]":"18.6","Cell RNA - EFO-21 [nTPM]":"22.5","Cell RNA - fHDF\/TERT166 [nTPM]":"19.2","Cell RNA - GAMG [nTPM]":"25.8","Cell RNA - HaCaT [nTPM]":"14.9","Cell RNA - HAP1 [nTPM]":"20.4","Cell RNA - HBEC3-KT [nTPM]":"20.4","Cell RNA - HBF TERT88 [nTPM]":"19.1","Cell RNA - HDLM-2 [nTPM]":"50.2","Cell RNA - HEK 293 [nTPM]":"13.9","Cell RNA - HEL [nTPM]":"18.2","Cell RNA - HeLa [nTPM]":"11.7","Cell RNA - Hep G2 [nTPM]":"10.3","Cell RNA - HHSteC [nTPM]":"12.0","Cell RNA - HL-60 [nTPM]":"21.4","Cell RNA - HMC-1 [nTPM]":"54.5","Cell RNA - HSkMC [nTPM]":"11.4","Cell RNA - hTCEpi [nTPM]":"13.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.1","Cell RNA - hTERT-HME1 [nTPM]":"18.3","Cell RNA - hTERT-RPE1 [nTPM]":"10.9","Cell RNA - HUVEC TERT2 [nTPM]":"13.9","Cell RNA - JURKAT [nTPM]":"27.8","Cell RNA - K-562 [nTPM]":"18.2","Cell RNA - Karpas-707 [nTPM]":"57.4","Cell RNA - LHCN-M2 [nTPM]":"11.8","Cell RNA - MCF7 [nTPM]":"23.6","Cell RNA - MOLT-4 [nTPM]":"46.2","Cell RNA - NB-4 [nTPM]":"12.6","Cell RNA - NTERA-2 [nTPM]":"8.0","Cell RNA - OE19 [nTPM]":"10.7","Cell RNA - PC-3 [nTPM]":"19.2","Cell RNA - REH [nTPM]":"25.5","Cell RNA - RH-30 [nTPM]":"19.8","Cell RNA - RPMI-8226 [nTPM]":"11.7","Cell RNA - RPTEC TERT1 [nTPM]":"16.8","Cell RNA - RT4 [nTPM]":"29.3","Cell RNA - SCLC-21H [nTPM]":"38.3","Cell RNA - SH-SY5Y [nTPM]":"13.8","Cell RNA - SiHa [nTPM]":"19.8","Cell RNA - SK-BR-3 [nTPM]":"14.1","Cell RNA - SK-MEL-30 [nTPM]":"13.0","Cell RNA - SuSa [nTPM]":"6.6","Cell RNA - T-47d [nTPM]":"13.1","Cell RNA - THP-1 [nTPM]":"24.2","Cell RNA - TIME [nTPM]":"29.9","Cell RNA - U-138 MG [nTPM]":"18.0","Cell RNA - U-2 OS [nTPM]":"14.8","Cell RNA - U-2197 [nTPM]":"48.0","Cell RNA - U-251 MG [nTPM]":"27.8","Cell RNA - U-266\/70 [nTPM]":"42.2","Cell RNA - U-266\/84 [nTPM]":"51.7","Cell RNA - U-698 [nTPM]":"36.0","Cell RNA - U-87 MG [nTPM]":"20.5","Cell RNA - U-937 [nTPM]":"10.8","Cell RNA - WM-115 [nTPM]":"21.8","Blood RNA - basophil [nTPM]":"3.3","Blood RNA - classical monocyte [nTPM]":"5.1","Blood RNA - eosinophil [nTPM]":"1.8","Blood RNA - gdT-cell [nTPM]":"2.9","Blood RNA - intermediate monocyte [nTPM]":"4.0","Blood RNA - MAIT T-cell [nTPM]":"2.4","Blood RNA - memory B-cell [nTPM]":"10.0","Blood RNA - memory CD4 T-cell [nTPM]":"4.2","Blood RNA - memory CD8 T-cell [nTPM]":"2.6","Blood RNA - myeloid DC [nTPM]":"3.6","Blood RNA - naive B-cell [nTPM]":"9.5","Blood RNA - naive CD4 T-cell [nTPM]":"3.0","Blood RNA - naive CD8 T-cell [nTPM]":"2.1","Blood RNA - neutrophil [nTPM]":"3.8","Blood RNA - NK-cell [nTPM]":"2.4","Blood RNA - non-classical monocyte [nTPM]":"2.5","Blood RNA - plasmacytoid DC [nTPM]":"5.9","Blood RNA - T-reg [nTPM]":"3.8","Blood RNA - total PBMC [nTPM]":"5.0","Brain RNA - amygdala [nTPM]":"8.3","Brain RNA - basal ganglia [nTPM]":"8.7","Brain RNA - cerebellum [nTPM]":"6.3","Brain RNA - cerebral cortex [nTPM]":"14.5","Brain RNA - hippocampal formation [nTPM]":"15.6","Brain RNA - hypothalamus [nTPM]":"12.1","Brain RNA - medulla oblongata [nTPM]":"9.8","Brain RNA - midbrain [nTPM]":"9.9","Brain RNA - pons [nTPM]":"9.5","Brain RNA - spinal cord [nTPM]":"8.1","Brain RNA - thalamus [nTPM]":"12.8","Brain RNA - white matter [nTPM]":"8.0","Single Cell Type RNA - Adipocytes [nTPM]":"4.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.9","Single Cell Type RNA - Astrocytes [nTPM]":"54.5","Single Cell Type RNA - B-cells [nTPM]":"43.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"20.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.2","Single Cell Type RNA - Bipolar cells [nTPM]":"42.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"13.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.3","Single Cell Type RNA - dendritic cells [nTPM]":"12.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"15.8","Single Cell Type RNA - Early spermatids [nTPM]":"9.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.5","Single Cell Type RNA - Endothelial cells [nTPM]":"8.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.4","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"108.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.7","Single Cell Type RNA - Fibroblasts [nTPM]":"11.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.2","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"3.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"5.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.9","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"63.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.8","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"8.7","Single Cell Type RNA - Langerhans cells [nTPM]":"29.5","Single Cell Type RNA - Late spermatids [nTPM]":"7.6","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"20.3","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"18.1","Single Cell Type RNA - Muller glia cells [nTPM]":"5.4","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"63.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"43.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.6","Single Cell Type RNA - Paneth cells [nTPM]":"5.9","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"42.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"28.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"16.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.4","Single Cell Type RNA - Spermatocytes [nTPM]":"14.2","Single Cell Type RNA - Spermatogonia [nTPM]":"33.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - T-cells [nTPM]":"21.9","Single Cell Type RNA - Theca cells [nTPM]":"1.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.3","Single Cell Type RNA - Urothelial cells [nTPM]":"24.9"},{"Gene":"TRAF3IP2","Gene synonym":["ACT1","C6orf2","C6orf4","C6orf5","C6orf6","CIKS","DKFZP586G0522"],"Ensembl":"ENSG00000056972","Gene description":"TRAF3 interacting protein 2","Uniprot":["O43734"],"Chromosome":"6","Position":"111555381-111606906","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Inflammatory response","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"61.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-2197":"149.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036352"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA036352":"AB_10672085"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.21e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.73e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.93e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.16e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Tissue RNA - adipose tissue [nTPM]":"19.7","Tissue RNA - adrenal gland [nTPM]":"16.3","Tissue RNA - amygdala [nTPM]":"24.8","Tissue RNA - appendix [nTPM]":"19.5","Tissue RNA - basal ganglia [nTPM]":"24.8","Tissue RNA - bone marrow [nTPM]":"32.4","Tissue RNA - breast [nTPM]":"19.9","Tissue RNA - cerebellum [nTPM]":"24.3","Tissue RNA - cerebral cortex [nTPM]":"29.4","Tissue RNA - cervix [nTPM]":"24.9","Tissue RNA - choroid plexus [nTPM]":"23.7","Tissue RNA - colon [nTPM]":"34.0","Tissue RNA - duodenum [nTPM]":"28.6","Tissue RNA - endometrium 1 [nTPM]":"36.2","Tissue RNA - epididymis [nTPM]":"47.2","Tissue RNA - esophagus [nTPM]":"26.5","Tissue RNA - fallopian tube [nTPM]":"34.7","Tissue RNA - gallbladder [nTPM]":"14.2","Tissue RNA - heart muscle [nTPM]":"8.3","Tissue RNA - hippocampal formation [nTPM]":"24.4","Tissue RNA - hypothalamus [nTPM]":"26.0","Tissue RNA - kidney [nTPM]":"9.3","Tissue RNA - liver [nTPM]":"8.6","Tissue RNA - lung [nTPM]":"17.5","Tissue RNA - lymph node [nTPM]":"16.3","Tissue RNA - medulla oblongata [nTPM]":"27.2","Tissue RNA - midbrain [nTPM]":"28.2","Tissue RNA - ovary [nTPM]":"13.9","Tissue RNA - pancreas [nTPM]":"21.6","Tissue RNA - parathyroid gland [nTPM]":"13.6","Tissue RNA - pituitary gland [nTPM]":"9.3","Tissue RNA - placenta [nTPM]":"14.2","Tissue RNA - pons [nTPM]":"25.6","Tissue RNA - prostate [nTPM]":"19.2","Tissue RNA - rectum [nTPM]":"26.4","Tissue RNA - retina [nTPM]":"5.9","Tissue RNA - salivary gland [nTPM]":"25.3","Tissue RNA - seminal vesicle [nTPM]":"30.8","Tissue RNA - skeletal muscle [nTPM]":"11.4","Tissue RNA - skin 1 [nTPM]":"35.0","Tissue RNA - small intestine [nTPM]":"25.1","Tissue RNA - smooth muscle [nTPM]":"22.1","Tissue RNA - spinal cord [nTPM]":"21.7","Tissue RNA - spleen [nTPM]":"6.8","Tissue RNA - stomach 1 [nTPM]":"35.5","Tissue RNA - testis [nTPM]":"3.0","Tissue RNA - thalamus [nTPM]":"28.7","Tissue RNA - thymus [nTPM]":"21.0","Tissue RNA - thyroid gland [nTPM]":"14.8","Tissue RNA - tongue [nTPM]":"14.8","Tissue RNA - tonsil [nTPM]":"22.5","Tissue RNA - urinary bladder [nTPM]":"26.5","Tissue RNA - vagina [nTPM]":"18.1","Tissue RNA - white matter [nTPM]":"22.9","Cell RNA - A-431 [nTPM]":"32.2","Cell RNA - A549 [nTPM]":"11.0","Cell RNA - AF22 [nTPM]":"6.8","Cell RNA - AN3-CA [nTPM]":"15.7","Cell RNA - ASC diff [nTPM]":"35.9","Cell RNA - ASC TERT1 [nTPM]":"39.0","Cell RNA - BEWO [nTPM]":"15.6","Cell RNA - BJ [nTPM]":"39.8","Cell RNA - BJ hTERT+ [nTPM]":"62.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.1","Cell RNA - CACO-2 [nTPM]":"8.7","Cell RNA - CAPAN-2 [nTPM]":"14.1","Cell RNA - Daudi [nTPM]":"6.2","Cell RNA - EFO-21 [nTPM]":"13.2","Cell RNA - fHDF\/TERT166 [nTPM]":"33.5","Cell RNA - GAMG [nTPM]":"35.5","Cell RNA - HaCaT [nTPM]":"58.2","Cell RNA - HAP1 [nTPM]":"8.0","Cell RNA - HBEC3-KT [nTPM]":"86.2","Cell RNA - HBF TERT88 [nTPM]":"18.4","Cell RNA - HDLM-2 [nTPM]":"43.2","Cell RNA - HEK 293 [nTPM]":"11.6","Cell RNA - HEL [nTPM]":"12.7","Cell RNA - HeLa [nTPM]":"10.6","Cell RNA - Hep G2 [nTPM]":"11.9","Cell RNA - HHSteC [nTPM]":"13.9","Cell RNA - HL-60 [nTPM]":"6.9","Cell RNA - HMC-1 [nTPM]":"22.6","Cell RNA - HSkMC [nTPM]":"47.1","Cell RNA - hTCEpi [nTPM]":"57.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"29.9","Cell RNA - hTERT-HME1 [nTPM]":"110.1","Cell RNA - hTERT-RPE1 [nTPM]":"24.9","Cell RNA - HUVEC TERT2 [nTPM]":"20.0","Cell RNA - JURKAT [nTPM]":"15.2","Cell RNA - K-562 [nTPM]":"13.6","Cell RNA - Karpas-707 [nTPM]":"1.9","Cell RNA - LHCN-M2 [nTPM]":"13.2","Cell RNA - MCF7 [nTPM]":"22.0","Cell RNA - MOLT-4 [nTPM]":"51.2","Cell RNA - NB-4 [nTPM]":"19.4","Cell RNA - NTERA-2 [nTPM]":"9.0","Cell RNA - OE19 [nTPM]":"30.6","Cell RNA - PC-3 [nTPM]":"8.8","Cell RNA - REH [nTPM]":"53.3","Cell RNA - RH-30 [nTPM]":"12.4","Cell RNA - RPMI-8226 [nTPM]":"2.7","Cell RNA - RPTEC TERT1 [nTPM]":"29.5","Cell RNA - RT4 [nTPM]":"52.4","Cell RNA - SCLC-21H [nTPM]":"27.3","Cell RNA - SH-SY5Y [nTPM]":"6.9","Cell RNA - SiHa [nTPM]":"12.1","Cell RNA - SK-BR-3 [nTPM]":"71.8","Cell RNA - SK-MEL-30 [nTPM]":"47.8","Cell RNA - SuSa [nTPM]":"12.7","Cell RNA - T-47d [nTPM]":"31.6","Cell RNA - THP-1 [nTPM]":"18.0","Cell RNA - TIME [nTPM]":"9.2","Cell RNA - U-138 MG [nTPM]":"19.2","Cell RNA - U-2 OS [nTPM]":"7.6","Cell RNA - U-2197 [nTPM]":"149.7","Cell RNA - U-251 MG [nTPM]":"35.5","Cell RNA - U-266\/70 [nTPM]":"0.8","Cell RNA - U-266\/84 [nTPM]":"12.4","Cell RNA - U-698 [nTPM]":"16.8","Cell RNA - U-87 MG [nTPM]":"45.8","Cell RNA - U-937 [nTPM]":"10.8","Cell RNA - WM-115 [nTPM]":"50.1","Blood RNA - basophil [nTPM]":"25.8","Blood RNA - classical monocyte [nTPM]":"2.5","Blood RNA - eosinophil [nTPM]":"5.3","Blood RNA - gdT-cell [nTPM]":"3.8","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"12.7","Blood RNA - memory B-cell [nTPM]":"6.4","Blood RNA - memory CD4 T-cell [nTPM]":"7.6","Blood RNA - memory CD8 T-cell [nTPM]":"5.6","Blood RNA - myeloid DC [nTPM]":"2.6","Blood RNA - naive B-cell [nTPM]":"8.6","Blood RNA - naive CD4 T-cell [nTPM]":"7.6","Blood RNA - naive CD8 T-cell [nTPM]":"7.4","Blood RNA - neutrophil [nTPM]":"3.5","Blood RNA - NK-cell [nTPM]":"5.7","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"17.9","Blood RNA - total PBMC [nTPM]":"3.1","Brain RNA - amygdala [nTPM]":"24.8","Brain RNA - basal ganglia [nTPM]":"24.8","Brain RNA - cerebellum [nTPM]":"24.3","Brain RNA - cerebral cortex [nTPM]":"29.4","Brain RNA - hippocampal formation [nTPM]":"24.4","Brain RNA - hypothalamus [nTPM]":"26.0","Brain RNA - medulla oblongata [nTPM]":"27.2","Brain RNA - midbrain [nTPM]":"28.2","Brain RNA - pons [nTPM]":"25.6","Brain RNA - spinal cord [nTPM]":"21.7","Brain RNA - thalamus [nTPM]":"28.7","Brain RNA - white matter [nTPM]":"22.9","Single Cell Type RNA - Adipocytes [nTPM]":"24.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.8","Single Cell Type RNA - Astrocytes [nTPM]":"26.1","Single Cell Type RNA - B-cells [nTPM]":"10.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"61.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"46.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"7.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"21.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.3","Single Cell Type RNA - dendritic cells [nTPM]":"3.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"30.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"35.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.5","Single Cell Type RNA - Endothelial cells [nTPM]":"18.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.2","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"31.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"28.8","Single Cell Type RNA - Fibroblasts [nTPM]":"14.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"32.7","Single Cell Type RNA - granulocytes [nTPM]":"20.2","Single Cell Type RNA - Granulosa cells [nTPM]":"7.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"5.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.0","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.9","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"10.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"5.8","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"6.2","Single Cell Type RNA - Muller glia cells [nTPM]":"14.2","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.2","Single Cell Type RNA - Paneth cells [nTPM]":"26.3","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"4.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"42.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"2.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.9","Single Cell Type RNA - T-cells [nTPM]":"7.9","Single Cell Type RNA - Theca cells [nTPM]":"4.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"21.9","Single Cell Type RNA - Urothelial cells [nTPM]":"45.0"},{"Gene":"TRAF7","Gene synonym":["DKFZp586I021","MGC7807","RFWD1","RNF119"],"Ensembl":"ENSG00000131653","Gene description":"TNF receptor associated factor 7","Uniprot":["Q6Q0C0"],"Chromosome":"16","Position":"2155698-2178129","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041229"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Vesicles"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA041229":"AB_10794194"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-2"},"Tissue RNA - adipose tissue [nTPM]":"29.1","Tissue RNA - adrenal gland [nTPM]":"29.4","Tissue RNA - amygdala [nTPM]":"16.5","Tissue RNA - appendix [nTPM]":"24.4","Tissue RNA - basal ganglia [nTPM]":"15.1","Tissue RNA - bone marrow [nTPM]":"35.0","Tissue RNA - breast [nTPM]":"28.2","Tissue RNA - cerebellum [nTPM]":"18.2","Tissue RNA - cerebral cortex [nTPM]":"23.0","Tissue RNA - cervix [nTPM]":"32.1","Tissue RNA - choroid plexus [nTPM]":"17.0","Tissue RNA - colon [nTPM]":"38.0","Tissue RNA - duodenum [nTPM]":"40.0","Tissue RNA - endometrium 1 [nTPM]":"31.2","Tissue RNA - epididymis [nTPM]":"11.6","Tissue RNA - esophagus [nTPM]":"54.6","Tissue RNA - fallopian tube [nTPM]":"30.4","Tissue RNA - gallbladder [nTPM]":"22.2","Tissue RNA - heart muscle [nTPM]":"21.3","Tissue RNA - hippocampal formation [nTPM]":"17.9","Tissue RNA - hypothalamus [nTPM]":"14.6","Tissue RNA - kidney [nTPM]":"28.1","Tissue RNA - liver [nTPM]":"51.5","Tissue RNA - lung [nTPM]":"33.2","Tissue RNA - lymph node [nTPM]":"22.9","Tissue RNA - medulla oblongata [nTPM]":"17.8","Tissue RNA - midbrain [nTPM]":"15.3","Tissue RNA - ovary [nTPM]":"23.5","Tissue RNA - pancreas [nTPM]":"37.4","Tissue RNA - parathyroid gland [nTPM]":"14.6","Tissue RNA - pituitary gland [nTPM]":"32.1","Tissue RNA - placenta [nTPM]":"20.6","Tissue RNA - pons [nTPM]":"14.8","Tissue RNA - prostate [nTPM]":"27.0","Tissue RNA - rectum [nTPM]":"17.4","Tissue RNA - retina [nTPM]":"8.5","Tissue RNA - salivary gland [nTPM]":"34.7","Tissue RNA - seminal vesicle [nTPM]":"16.5","Tissue RNA - skeletal muscle [nTPM]":"30.4","Tissue RNA - skin 1 [nTPM]":"47.7","Tissue RNA - small intestine [nTPM]":"35.2","Tissue RNA - smooth muscle [nTPM]":"18.8","Tissue RNA - spinal cord [nTPM]":"14.2","Tissue RNA - spleen [nTPM]":"34.5","Tissue RNA - stomach 1 [nTPM]":"35.6","Tissue RNA - testis [nTPM]":"14.8","Tissue RNA - thalamus [nTPM]":"17.7","Tissue RNA - thymus [nTPM]":"19.1","Tissue RNA - thyroid gland [nTPM]":"25.6","Tissue RNA - tongue [nTPM]":"9.9","Tissue RNA - tonsil [nTPM]":"18.6","Tissue RNA - urinary bladder [nTPM]":"34.5","Tissue RNA - vagina [nTPM]":"34.8","Tissue RNA - white matter [nTPM]":"14.3","Cell RNA - A-431 [nTPM]":"57.7","Cell RNA - A549 [nTPM]":"72.2","Cell RNA - AF22 [nTPM]":"40.3","Cell RNA - AN3-CA [nTPM]":"72.5","Cell RNA - ASC diff [nTPM]":"40.8","Cell RNA - ASC TERT1 [nTPM]":"76.5","Cell RNA - BEWO [nTPM]":"47.4","Cell RNA - BJ [nTPM]":"43.4","Cell RNA - BJ hTERT+ [nTPM]":"53.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"49.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"44.6","Cell RNA - CACO-2 [nTPM]":"88.2","Cell RNA - CAPAN-2 [nTPM]":"72.1","Cell RNA - Daudi [nTPM]":"36.6","Cell RNA - EFO-21 [nTPM]":"50.2","Cell RNA - fHDF\/TERT166 [nTPM]":"55.4","Cell RNA - GAMG [nTPM]":"31.8","Cell RNA - HaCaT [nTPM]":"65.9","Cell RNA - HAP1 [nTPM]":"38.1","Cell RNA - HBEC3-KT [nTPM]":"76.8","Cell RNA - HBF TERT88 [nTPM]":"18.8","Cell RNA - HDLM-2 [nTPM]":"58.3","Cell RNA - HEK 293 [nTPM]":"48.8","Cell RNA - HEL [nTPM]":"52.4","Cell RNA - HeLa [nTPM]":"98.5","Cell RNA - Hep G2 [nTPM]":"68.3","Cell RNA - HHSteC [nTPM]":"53.8","Cell RNA - HL-60 [nTPM]":"56.3","Cell RNA - HMC-1 [nTPM]":"72.7","Cell RNA - HSkMC [nTPM]":"76.2","Cell RNA - hTCEpi [nTPM]":"62.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"48.1","Cell RNA - hTERT-HME1 [nTPM]":"62.6","Cell RNA - hTERT-RPE1 [nTPM]":"41.0","Cell RNA - HUVEC TERT2 [nTPM]":"97.4","Cell RNA - JURKAT [nTPM]":"70.6","Cell RNA - K-562 [nTPM]":"57.1","Cell RNA - Karpas-707 [nTPM]":"47.9","Cell RNA - LHCN-M2 [nTPM]":"48.2","Cell RNA - MCF7 [nTPM]":"131.1","Cell RNA - MOLT-4 [nTPM]":"58.3","Cell RNA - NB-4 [nTPM]":"65.2","Cell RNA - NTERA-2 [nTPM]":"79.7","Cell RNA - OE19 [nTPM]":"78.7","Cell RNA - PC-3 [nTPM]":"34.8","Cell RNA - REH [nTPM]":"107.4","Cell RNA - RH-30 [nTPM]":"66.7","Cell RNA - RPMI-8226 [nTPM]":"74.2","Cell RNA - RPTEC TERT1 [nTPM]":"40.2","Cell RNA - RT4 [nTPM]":"30.4","Cell RNA - SCLC-21H [nTPM]":"80.9","Cell RNA - SH-SY5Y [nTPM]":"67.2","Cell RNA - SiHa [nTPM]":"36.3","Cell RNA - SK-BR-3 [nTPM]":"68.5","Cell RNA - SK-MEL-30 [nTPM]":"48.6","Cell RNA - SuSa [nTPM]":"20.9","Cell RNA - T-47d [nTPM]":"78.1","Cell RNA - THP-1 [nTPM]":"68.2","Cell RNA - TIME [nTPM]":"74.3","Cell RNA - U-138 MG [nTPM]":"60.2","Cell RNA - U-2 OS [nTPM]":"83.9","Cell RNA - U-2197 [nTPM]":"56.7","Cell RNA - U-251 MG [nTPM]":"48.2","Cell RNA - U-266\/70 [nTPM]":"69.2","Cell RNA - U-266\/84 [nTPM]":"55.0","Cell RNA - U-698 [nTPM]":"48.4","Cell RNA - U-87 MG [nTPM]":"34.4","Cell RNA - U-937 [nTPM]":"35.9","Cell RNA - WM-115 [nTPM]":"47.8","Blood RNA - basophil [nTPM]":"4.0","Blood RNA - classical monocyte [nTPM]":"9.1","Blood RNA - eosinophil [nTPM]":"7.3","Blood RNA - gdT-cell [nTPM]":"4.5","Blood RNA - intermediate monocyte [nTPM]":"12.4","Blood RNA - MAIT T-cell [nTPM]":"4.3","Blood RNA - memory B-cell [nTPM]":"5.5","Blood RNA - memory CD4 T-cell [nTPM]":"4.4","Blood RNA - memory CD8 T-cell [nTPM]":"4.7","Blood RNA - myeloid DC [nTPM]":"11.2","Blood RNA - naive B-cell [nTPM]":"3.9","Blood RNA - naive CD4 T-cell [nTPM]":"3.1","Blood RNA - naive CD8 T-cell [nTPM]":"3.8","Blood RNA - neutrophil [nTPM]":"6.2","Blood RNA - NK-cell [nTPM]":"2.9","Blood RNA - non-classical monocyte [nTPM]":"8.9","Blood RNA - plasmacytoid DC [nTPM]":"5.3","Blood RNA - T-reg [nTPM]":"6.5","Blood RNA - total PBMC [nTPM]":"5.3","Brain RNA - amygdala [nTPM]":"16.5","Brain RNA - basal ganglia [nTPM]":"15.1","Brain RNA - cerebellum [nTPM]":"18.2","Brain RNA - cerebral cortex [nTPM]":"23.0","Brain RNA - hippocampal formation [nTPM]":"17.9","Brain RNA - hypothalamus [nTPM]":"14.6","Brain RNA - medulla oblongata [nTPM]":"17.8","Brain RNA - midbrain [nTPM]":"15.3","Brain RNA - pons [nTPM]":"14.8","Brain RNA - spinal cord [nTPM]":"14.2","Brain RNA - thalamus [nTPM]":"17.7","Brain RNA - white matter [nTPM]":"14.3","Single Cell Type RNA - Adipocytes [nTPM]":"18.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.2","Single Cell Type RNA - Astrocytes [nTPM]":"12.4","Single Cell Type RNA - B-cells [nTPM]":"18.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"28.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"34.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.8","Single Cell Type RNA - Bipolar cells [nTPM]":"15.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"31.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"27.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"20.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.5","Single Cell Type RNA - dendritic cells [nTPM]":"17.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"56.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"39.0","Single Cell Type RNA - Early spermatids [nTPM]":"5.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"34.6","Single Cell Type RNA - Endothelial cells [nTPM]":"26.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"34.0","Single Cell Type RNA - Erythroid cells [nTPM]":"33.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"59.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"36.3","Single Cell Type RNA - Fibroblasts [nTPM]":"19.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"38.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"27.9","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"22.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.0","Single Cell Type RNA - Hepatocytes [nTPM]":"32.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"42.2","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"38.7","Single Cell Type RNA - Ionocytes [nTPM]":"34.6","Single Cell Type RNA - Kupffer cells [nTPM]":"41.8","Single Cell Type RNA - Langerhans cells [nTPM]":"21.3","Single Cell Type RNA - Late spermatids [nTPM]":"13.1","Single Cell Type RNA - Leydig cells [nTPM]":"24.8","Single Cell Type RNA - Macrophages [nTPM]":"26.8","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"33.9","Single Cell Type RNA - Muller glia cells [nTPM]":"12.6","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"53.0","Single Cell Type RNA - Paneth cells [nTPM]":"43.6","Single Cell Type RNA - Peritubular cells [nTPM]":"22.2","Single Cell Type RNA - Plasma cells [nTPM]":"24.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"33.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"80.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"29.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.3","Single Cell Type RNA - Spermatocytes [nTPM]":"8.5","Single Cell Type RNA - Spermatogonia [nTPM]":"25.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"50.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"32.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"26.7","Single Cell Type RNA - T-cells [nTPM]":"16.0","Single Cell Type RNA - Theca cells [nTPM]":"29.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"42.5","Single Cell Type RNA - Urothelial cells [nTPM]":"38.5"},{"Gene":"TRAIP","Gene synonym":["RNF206","TRIP"],"Ensembl":"ENSG00000183763","Gene description":"TRAF interacting protein","Uniprot":["Q9BWF2"],"Chromosome":"3","Position":"49828601-49856574","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Dwarfism","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"8.2","Spermatocytes":"15.6","Spermatogonia":"9.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"basal ganglia":"10.8"},"Antibody":["HPA036261","HPA036262"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA036261":"AB_10673348","HPA036262":"AB_2675029"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.77e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.5","Tissue RNA - adrenal gland [nTPM]":"1.0","Tissue RNA - amygdala [nTPM]":"1.6","Tissue RNA - appendix [nTPM]":"1.8","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"6.8","Tissue RNA - breast [nTPM]":"1.9","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"1.8","Tissue RNA - cervix [nTPM]":"2.0","Tissue RNA - choroid plexus [nTPM]":"0.4","Tissue RNA - colon [nTPM]":"2.3","Tissue RNA - duodenum [nTPM]":"1.5","Tissue RNA - endometrium 1 [nTPM]":"1.7","Tissue RNA - epididymis [nTPM]":"1.4","Tissue RNA - esophagus [nTPM]":"2.9","Tissue RNA - fallopian tube [nTPM]":"1.8","Tissue RNA - gallbladder [nTPM]":"1.0","Tissue RNA - heart muscle [nTPM]":"0.9","Tissue RNA - hippocampal formation [nTPM]":"1.6","Tissue RNA - hypothalamus [nTPM]":"0.9","Tissue RNA - kidney [nTPM]":"0.8","Tissue RNA - liver [nTPM]":"0.8","Tissue RNA - lung [nTPM]":"0.9","Tissue RNA - lymph node [nTPM]":"4.6","Tissue RNA - medulla oblongata [nTPM]":"0.6","Tissue RNA - midbrain [nTPM]":"0.6","Tissue RNA - ovary [nTPM]":"2.1","Tissue RNA - pancreas [nTPM]":"1.0","Tissue RNA - parathyroid gland [nTPM]":"0.8","Tissue RNA - pituitary gland [nTPM]":"1.2","Tissue RNA - placenta [nTPM]":"1.6","Tissue RNA - pons [nTPM]":"0.7","Tissue RNA - prostate [nTPM]":"1.4","Tissue RNA - rectum [nTPM]":"2.9","Tissue RNA - retina [nTPM]":"2.3","Tissue RNA - salivary gland [nTPM]":"1.2","Tissue RNA - seminal vesicle [nTPM]":"0.9","Tissue RNA - skeletal muscle [nTPM]":"2.0","Tissue RNA - skin 1 [nTPM]":"4.2","Tissue RNA - small intestine [nTPM]":"2.0","Tissue RNA - smooth muscle [nTPM]":"2.1","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"1.9","Tissue RNA - stomach 1 [nTPM]":"1.2","Tissue RNA - testis [nTPM]":"7.9","Tissue RNA - thalamus [nTPM]":"1.3","Tissue RNA - thymus [nTPM]":"5.3","Tissue RNA - thyroid gland [nTPM]":"1.4","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"4.4","Tissue RNA - urinary bladder [nTPM]":"1.3","Tissue RNA - vagina [nTPM]":"1.9","Tissue RNA - white matter [nTPM]":"0.9","Cell RNA - A-431 [nTPM]":"10.4","Cell RNA - A549 [nTPM]":"12.4","Cell RNA - AF22 [nTPM]":"17.4","Cell RNA - AN3-CA [nTPM]":"17.6","Cell RNA - ASC diff [nTPM]":"1.6","Cell RNA - ASC TERT1 [nTPM]":"2.4","Cell RNA - BEWO [nTPM]":"14.4","Cell RNA - BJ [nTPM]":"12.4","Cell RNA - BJ hTERT+ [nTPM]":"5.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"25.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.0","Cell RNA - CACO-2 [nTPM]":"15.2","Cell RNA - CAPAN-2 [nTPM]":"11.6","Cell RNA - Daudi [nTPM]":"25.5","Cell RNA - EFO-21 [nTPM]":"8.5","Cell RNA - fHDF\/TERT166 [nTPM]":"7.1","Cell RNA - GAMG [nTPM]":"17.7","Cell RNA - HaCaT [nTPM]":"13.4","Cell RNA - HAP1 [nTPM]":"18.5","Cell RNA - HBEC3-KT [nTPM]":"14.0","Cell RNA - HBF TERT88 [nTPM]":"18.8","Cell RNA - HDLM-2 [nTPM]":"14.7","Cell RNA - HEK 293 [nTPM]":"12.2","Cell RNA - HEL [nTPM]":"19.2","Cell RNA - HeLa [nTPM]":"16.3","Cell RNA - Hep G2 [nTPM]":"13.6","Cell RNA - HHSteC [nTPM]":"0.7","Cell RNA - HL-60 [nTPM]":"15.8","Cell RNA - HMC-1 [nTPM]":"15.4","Cell RNA - HSkMC [nTPM]":"1.6","Cell RNA - hTCEpi [nTPM]":"2.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.4","Cell RNA - hTERT-HME1 [nTPM]":"10.7","Cell RNA - hTERT-RPE1 [nTPM]":"3.0","Cell RNA - HUVEC TERT2 [nTPM]":"6.7","Cell RNA - JURKAT [nTPM]":"22.3","Cell RNA - K-562 [nTPM]":"14.0","Cell RNA - Karpas-707 [nTPM]":"17.8","Cell RNA - LHCN-M2 [nTPM]":"11.4","Cell RNA - MCF7 [nTPM]":"15.1","Cell RNA - MOLT-4 [nTPM]":"26.5","Cell RNA - NB-4 [nTPM]":"20.1","Cell RNA - NTERA-2 [nTPM]":"14.0","Cell RNA - OE19 [nTPM]":"12.3","Cell RNA - PC-3 [nTPM]":"20.3","Cell RNA - REH [nTPM]":"14.4","Cell RNA - RH-30 [nTPM]":"11.7","Cell RNA - RPMI-8226 [nTPM]":"14.8","Cell RNA - RPTEC TERT1 [nTPM]":"4.6","Cell RNA - RT4 [nTPM]":"14.2","Cell RNA - SCLC-21H [nTPM]":"8.4","Cell RNA - SH-SY5Y [nTPM]":"14.4","Cell RNA - SiHa [nTPM]":"13.6","Cell RNA - SK-BR-3 [nTPM]":"11.3","Cell RNA - SK-MEL-30 [nTPM]":"8.8","Cell RNA - SuSa [nTPM]":"12.4","Cell RNA - T-47d [nTPM]":"10.2","Cell RNA - THP-1 [nTPM]":"22.4","Cell RNA - TIME [nTPM]":"5.2","Cell RNA - U-138 MG [nTPM]":"16.1","Cell RNA - U-2 OS [nTPM]":"19.0","Cell RNA - U-2197 [nTPM]":"22.5","Cell RNA - U-251 MG [nTPM]":"24.4","Cell RNA - U-266\/70 [nTPM]":"13.0","Cell RNA - U-266\/84 [nTPM]":"33.7","Cell RNA - U-698 [nTPM]":"27.3","Cell RNA - U-87 MG [nTPM]":"8.1","Cell RNA - U-937 [nTPM]":"21.2","Cell RNA - WM-115 [nTPM]":"14.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.9","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.9","Blood RNA - memory B-cell [nTPM]":"2.9","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"2.1","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"1.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.1","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"1.2","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"1.6","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"1.8","Brain RNA - hippocampal formation [nTPM]":"1.6","Brain RNA - hypothalamus [nTPM]":"0.9","Brain RNA - medulla oblongata [nTPM]":"0.6","Brain RNA - midbrain [nTPM]":"0.6","Brain RNA - pons [nTPM]":"0.7","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"1.3","Brain RNA - white matter [nTPM]":"0.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"1.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"2.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.2","Single Cell Type RNA - dendritic cells [nTPM]":"1.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.0","Single Cell Type RNA - Early spermatids [nTPM]":"4.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.9","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.2","Single Cell Type RNA - Fibroblasts [nTPM]":"2.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"5.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"4.8","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"1.8","Single Cell Type RNA - Muller glia cells [nTPM]":"1.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"4.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.7","Single Cell Type RNA - Spermatocytes [nTPM]":"15.6","Single Cell Type RNA - Spermatogonia [nTPM]":"9.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"1.2","Single Cell Type RNA - Theca cells [nTPM]":"1.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"TRDN","Gene synonym":["TRISK"],"Ensembl":"ENSG00000186439","Gene description":"Triadin","Uniprot":["Q13061"],"Chromosome":"6","Position":"123216339-123637093","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"421.6","skeletal muscle":"1944.1","tongue":"1018.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Cardiomyocytes":"1145.1","Muller glia cells":"765.7","Skeletal myocytes":"398.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"head and neck cancer":"2.2","prostate cancer":"0.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"1.9"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"10","RNA mouse brain regional specific nTPM":{"olfactory bulb":"11.0"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"23","RNA pig brain regional specific nTPM":{"olfactory bulb":"28.9"},"Antibody":["HPA038226","HPA058226"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA038226":"AB_10795574","HPA058226":"AB_2683643"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.93e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Tissue RNA - adipose tissue [nTPM]":"16.3","Tissue RNA - adrenal gland [nTPM]":"2.6","Tissue RNA - amygdala [nTPM]":"4.2","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"3.7","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"2.0","Tissue RNA - cerebellum [nTPM]":"4.0","Tissue RNA - cerebral cortex [nTPM]":"5.8","Tissue RNA - cervix [nTPM]":"0.7","Tissue RNA - choroid plexus [nTPM]":"3.1","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"1.7","Tissue RNA - epididymis [nTPM]":"10.4","Tissue RNA - esophagus [nTPM]":"18.5","Tissue RNA - fallopian tube [nTPM]":"12.5","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"421.6","Tissue RNA - hippocampal formation [nTPM]":"3.0","Tissue RNA - hypothalamus [nTPM]":"12.5","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"6.7","Tissue RNA - midbrain [nTPM]":"7.0","Tissue RNA - ovary [nTPM]":"1.3","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"15.3","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"7.9","Tissue RNA - prostate [nTPM]":"17.0","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"83.5","Tissue RNA - salivary gland [nTPM]":"13.1","Tissue RNA - seminal vesicle [nTPM]":"0.9","Tissue RNA - skeletal muscle [nTPM]":"1944.1","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"1.0","Tissue RNA - spinal cord [nTPM]":"9.2","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"5.1","Tissue RNA - thalamus [nTPM]":"10.2","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"1018.2","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"6.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.5","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.9","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.8","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.8","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.2","Brain RNA - basal ganglia [nTPM]":"3.7","Brain RNA - cerebellum [nTPM]":"4.0","Brain RNA - cerebral cortex [nTPM]":"5.8","Brain RNA - hippocampal formation [nTPM]":"3.0","Brain RNA - hypothalamus [nTPM]":"12.5","Brain RNA - medulla oblongata [nTPM]":"6.7","Brain RNA - midbrain [nTPM]":"7.0","Brain RNA - pons [nTPM]":"7.9","Brain RNA - spinal cord [nTPM]":"9.2","Brain RNA - thalamus [nTPM]":"10.2","Brain RNA - white matter [nTPM]":"6.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"4.2","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"7.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1145.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"68.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"6.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"38.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"35.5","Single Cell Type RNA - Leydig cells [nTPM]":"13.1","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"765.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"11.3","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"398.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"TREH","Gene synonym":["MGC129621","TRE","TREA"],"Ensembl":"ENSG00000118094","Gene description":"Trehalase","Uniprot":["O43280"],"Chromosome":"11","Position":"118657316-118679690","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"66.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Late spermatids":"315.7","Proximal enterocytes":"186.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"1.6"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039913","HPA042045"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA039913":"AB_10674988","HPA042045":"AB_2677817"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.76e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.33e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.7","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"1.6","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"3.7","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"3.8","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.6","Tissue RNA - duodenum [nTPM]":"60.0","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"1.6","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"2.6","Tissue RNA - heart muscle [nTPM]":"1.0","Tissue RNA - hippocampal formation [nTPM]":"1.1","Tissue RNA - hypothalamus [nTPM]":"2.7","Tissue RNA - kidney [nTPM]":"13.4","Tissue RNA - liver [nTPM]":"6.1","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"2.1","Tissue RNA - midbrain [nTPM]":"2.0","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"1.8","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"1.9","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"1.3","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"66.3","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"1.7","Tissue RNA - testis [nTPM]":"1.8","Tissue RNA - thalamus [nTPM]":"2.5","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"6.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"1.6","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.6","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.5","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.6","Brain RNA - basal ganglia [nTPM]":"3.7","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"3.8","Brain RNA - hippocampal formation [nTPM]":"1.1","Brain RNA - hypothalamus [nTPM]":"2.7","Brain RNA - medulla oblongata [nTPM]":"2.1","Brain RNA - midbrain [nTPM]":"2.0","Brain RNA - pons [nTPM]":"1.9","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"2.5","Brain RNA - white matter [nTPM]":"6.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"45.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"315.7","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.9","Single Cell Type RNA - Paneth cells [nTPM]":"6.3","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"186.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"32.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"1.7","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.7","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"TREX1","Gene synonym":["AGS1","DRN3"],"Ensembl":"ENSG00000213689","Gene description":"Three prime repair exonuclease 1","Uniprot":["Q9NSU2"],"Chromosome":"3","Position":"48465811-48467645","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Exonuclease","Hydrolase","Nuclease"],"Disease involvement":["Aicardi-Goutieres syndrome","Disease variant","Neurodegeneration","Systemic lupus erythematosus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"53.6","Club cells":"24.5","Ionocytes":"40.7","Langerhans cells":"22.6","Melanocytes":"24.9","Respiratory ciliated cells":"29.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+ SV40 Large T+ RasG12V":"67.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035437","HPA046721"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA035437":"AB_10672092","HPA046721":"AB_2732531"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"9.9","Tissue RNA - adrenal gland [nTPM]":"14.3","Tissue RNA - amygdala [nTPM]":"32.7","Tissue RNA - appendix [nTPM]":"16.5","Tissue RNA - basal ganglia [nTPM]":"33.4","Tissue RNA - bone marrow [nTPM]":"28.7","Tissue RNA - breast [nTPM]":"12.2","Tissue RNA - cerebellum [nTPM]":"33.2","Tissue RNA - cerebral cortex [nTPM]":"42.1","Tissue RNA - cervix [nTPM]":"13.8","Tissue RNA - choroid plexus [nTPM]":"39.8","Tissue RNA - colon [nTPM]":"12.4","Tissue RNA - duodenum [nTPM]":"11.1","Tissue RNA - endometrium 1 [nTPM]":"7.7","Tissue RNA - epididymis [nTPM]":"11.4","Tissue RNA - esophagus [nTPM]":"19.2","Tissue RNA - fallopian tube [nTPM]":"15.5","Tissue RNA - gallbladder [nTPM]":"13.8","Tissue RNA - heart muscle [nTPM]":"10.7","Tissue RNA - hippocampal formation [nTPM]":"33.0","Tissue RNA - hypothalamus [nTPM]":"32.7","Tissue RNA - kidney [nTPM]":"12.2","Tissue RNA - liver [nTPM]":"12.8","Tissue RNA - lung [nTPM]":"13.8","Tissue RNA - lymph node [nTPM]":"26.6","Tissue RNA - medulla oblongata [nTPM]":"33.0","Tissue RNA - midbrain [nTPM]":"34.2","Tissue RNA - ovary [nTPM]":"7.4","Tissue RNA - pancreas [nTPM]":"13.1","Tissue RNA - parathyroid gland [nTPM]":"11.3","Tissue RNA - pituitary gland [nTPM]":"20.6","Tissue RNA - placenta [nTPM]":"8.4","Tissue RNA - pons [nTPM]":"34.3","Tissue RNA - prostate [nTPM]":"16.6","Tissue RNA - rectum [nTPM]":"9.9","Tissue RNA - retina [nTPM]":"1.9","Tissue RNA - salivary gland [nTPM]":"36.5","Tissue RNA - seminal vesicle [nTPM]":"15.4","Tissue RNA - skeletal muscle [nTPM]":"9.7","Tissue RNA - skin 1 [nTPM]":"26.4","Tissue RNA - small intestine [nTPM]":"12.0","Tissue RNA - smooth muscle [nTPM]":"7.0","Tissue RNA - spinal cord [nTPM]":"33.8","Tissue RNA - spleen [nTPM]":"25.0","Tissue RNA - stomach 1 [nTPM]":"13.7","Tissue RNA - testis [nTPM]":"4.0","Tissue RNA - thalamus [nTPM]":"33.5","Tissue RNA - thymus [nTPM]":"18.1","Tissue RNA - thyroid gland [nTPM]":"8.4","Tissue RNA - tongue [nTPM]":"13.8","Tissue RNA - tonsil [nTPM]":"18.1","Tissue RNA - urinary bladder [nTPM]":"13.1","Tissue RNA - vagina [nTPM]":"10.4","Tissue RNA - white matter [nTPM]":"33.7","Cell RNA - A-431 [nTPM]":"19.2","Cell RNA - A549 [nTPM]":"18.1","Cell RNA - AF22 [nTPM]":"13.3","Cell RNA - AN3-CA [nTPM]":"10.3","Cell RNA - ASC diff [nTPM]":"18.1","Cell RNA - ASC TERT1 [nTPM]":"17.5","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"6.7","Cell RNA - BJ hTERT+ [nTPM]":"29.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"46.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"67.5","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"21.8","Cell RNA - Daudi [nTPM]":"23.8","Cell RNA - EFO-21 [nTPM]":"11.7","Cell RNA - fHDF\/TERT166 [nTPM]":"24.4","Cell RNA - GAMG [nTPM]":"44.8","Cell RNA - HaCaT [nTPM]":"21.4","Cell RNA - HAP1 [nTPM]":"0.9","Cell RNA - HBEC3-KT [nTPM]":"27.2","Cell RNA - HBF TERT88 [nTPM]":"6.7","Cell RNA - HDLM-2 [nTPM]":"19.9","Cell RNA - HEK 293 [nTPM]":"1.6","Cell RNA - HEL [nTPM]":"13.5","Cell RNA - HeLa [nTPM]":"58.1","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"20.1","Cell RNA - HL-60 [nTPM]":"12.8","Cell RNA - HMC-1 [nTPM]":"9.3","Cell RNA - HSkMC [nTPM]":"16.2","Cell RNA - hTCEpi [nTPM]":"2.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.9","Cell RNA - hTERT-HME1 [nTPM]":"9.8","Cell RNA - hTERT-RPE1 [nTPM]":"9.8","Cell RNA - HUVEC TERT2 [nTPM]":"20.4","Cell RNA - JURKAT [nTPM]":"16.9","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"32.6","Cell RNA - LHCN-M2 [nTPM]":"20.7","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"17.3","Cell RNA - NB-4 [nTPM]":"8.6","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"11.0","Cell RNA - PC-3 [nTPM]":"11.2","Cell RNA - REH [nTPM]":"14.4","Cell RNA - RH-30 [nTPM]":"4.9","Cell RNA - RPMI-8226 [nTPM]":"43.2","Cell RNA - RPTEC TERT1 [nTPM]":"13.4","Cell RNA - RT4 [nTPM]":"3.8","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"8.1","Cell RNA - SiHa [nTPM]":"21.8","Cell RNA - SK-BR-3 [nTPM]":"29.6","Cell RNA - SK-MEL-30 [nTPM]":"15.4","Cell RNA - SuSa [nTPM]":"0.9","Cell RNA - T-47d [nTPM]":"0.8","Cell RNA - THP-1 [nTPM]":"20.3","Cell RNA - TIME [nTPM]":"22.2","Cell RNA - U-138 MG [nTPM]":"8.5","Cell RNA - U-2 OS [nTPM]":"9.2","Cell RNA - U-2197 [nTPM]":"21.8","Cell RNA - U-251 MG [nTPM]":"14.2","Cell RNA - U-266\/70 [nTPM]":"26.4","Cell RNA - U-266\/84 [nTPM]":"16.9","Cell RNA - U-698 [nTPM]":"10.4","Cell RNA - U-87 MG [nTPM]":"21.5","Cell RNA - U-937 [nTPM]":"25.4","Cell RNA - WM-115 [nTPM]":"7.5","Blood RNA - basophil [nTPM]":"7.7","Blood RNA - classical monocyte [nTPM]":"142.3","Blood RNA - eosinophil [nTPM]":"11.0","Blood RNA - gdT-cell [nTPM]":"32.6","Blood RNA - intermediate monocyte [nTPM]":"119.2","Blood RNA - MAIT T-cell [nTPM]":"18.7","Blood RNA - memory B-cell [nTPM]":"86.8","Blood RNA - memory CD4 T-cell [nTPM]":"43.0","Blood RNA - memory CD8 T-cell [nTPM]":"31.4","Blood RNA - myeloid DC [nTPM]":"125.9","Blood RNA - naive B-cell [nTPM]":"87.5","Blood RNA - naive CD4 T-cell [nTPM]":"40.3","Blood RNA - naive CD8 T-cell [nTPM]":"33.8","Blood RNA - neutrophil [nTPM]":"82.2","Blood RNA - NK-cell [nTPM]":"30.9","Blood RNA - non-classical monocyte [nTPM]":"94.6","Blood RNA - plasmacytoid DC [nTPM]":"99.1","Blood RNA - T-reg [nTPM]":"43.3","Blood RNA - total PBMC [nTPM]":"78.6","Brain RNA - amygdala [nTPM]":"32.7","Brain RNA - basal ganglia [nTPM]":"33.4","Brain RNA - cerebellum [nTPM]":"33.2","Brain RNA - cerebral cortex [nTPM]":"42.1","Brain RNA - hippocampal formation [nTPM]":"33.0","Brain RNA - hypothalamus [nTPM]":"32.7","Brain RNA - medulla oblongata [nTPM]":"33.0","Brain RNA - midbrain [nTPM]":"34.2","Brain RNA - pons [nTPM]":"34.3","Brain RNA - spinal cord [nTPM]":"33.8","Brain RNA - thalamus [nTPM]":"33.5","Brain RNA - white matter [nTPM]":"33.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"2.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"53.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"24.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"4.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"4.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.8","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"22.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"2.0","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"1.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"3.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"2.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"TRIM2","Gene synonym":["CMT2R","KIAA0517","RNF86"],"Ensembl":"ENSG00000109654","Gene description":"Tripartite motif containing 2","Uniprot":["Q9C040"],"Chromosome":"4","Position":"153152163-153339319","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"116.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Oligodendrocytes":"1132.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory CD4 T-cell":"1.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"47.0","SK-MEL-30":"46.8"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035853","HPA035854"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA035853":"AB_10669533","HPA035854":"AB_10669659"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.58e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.8","Tissue RNA - adrenal gland [nTPM]":"11.8","Tissue RNA - amygdala [nTPM]":"29.5","Tissue RNA - appendix [nTPM]":"4.8","Tissue RNA - basal ganglia [nTPM]":"64.4","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"11.8","Tissue RNA - cerebellum [nTPM]":"38.6","Tissue RNA - cerebral cortex [nTPM]":"46.2","Tissue RNA - cervix [nTPM]":"23.6","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"21.6","Tissue RNA - duodenum [nTPM]":"17.4","Tissue RNA - endometrium 1 [nTPM]":"9.9","Tissue RNA - epididymis [nTPM]":"8.0","Tissue RNA - esophagus [nTPM]":"10.7","Tissue RNA - fallopian tube [nTPM]":"15.2","Tissue RNA - gallbladder [nTPM]":"12.6","Tissue RNA - heart muscle [nTPM]":"8.4","Tissue RNA - hippocampal formation [nTPM]":"48.0","Tissue RNA - hypothalamus [nTPM]":"34.8","Tissue RNA - kidney [nTPM]":"24.2","Tissue RNA - liver [nTPM]":"7.9","Tissue RNA - lung [nTPM]":"7.2","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"40.1","Tissue RNA - midbrain [nTPM]":"33.2","Tissue RNA - ovary [nTPM]":"12.8","Tissue RNA - pancreas [nTPM]":"12.7","Tissue RNA - parathyroid gland [nTPM]":"1.0","Tissue RNA - pituitary gland [nTPM]":"21.6","Tissue RNA - placenta [nTPM]":"2.5","Tissue RNA - pons [nTPM]":"56.3","Tissue RNA - prostate [nTPM]":"13.1","Tissue RNA - rectum [nTPM]":"19.3","Tissue RNA - retina [nTPM]":"19.4","Tissue RNA - salivary gland [nTPM]":"42.9","Tissue RNA - seminal vesicle [nTPM]":"13.4","Tissue RNA - skeletal muscle [nTPM]":"2.1","Tissue RNA - skin 1 [nTPM]":"7.1","Tissue RNA - small intestine [nTPM]":"17.3","Tissue RNA - smooth muscle [nTPM]":"7.0","Tissue RNA - spinal cord [nTPM]":"35.3","Tissue RNA - spleen [nTPM]":"10.6","Tissue RNA - stomach 1 [nTPM]":"27.4","Tissue RNA - testis [nTPM]":"1.9","Tissue RNA - thalamus [nTPM]":"37.9","Tissue RNA - thymus [nTPM]":"2.9","Tissue RNA - thyroid gland [nTPM]":"50.6","Tissue RNA - tongue [nTPM]":"3.0","Tissue RNA - tonsil [nTPM]":"3.9","Tissue RNA - urinary bladder [nTPM]":"12.0","Tissue RNA - vagina [nTPM]":"11.5","Tissue RNA - white matter [nTPM]":"116.2","Cell RNA - A-431 [nTPM]":"10.2","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"47.0","Cell RNA - AN3-CA [nTPM]":"24.2","Cell RNA - ASC diff [nTPM]":"22.0","Cell RNA - ASC TERT1 [nTPM]":"27.2","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"12.7","Cell RNA - BJ hTERT+ [nTPM]":"15.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.5","Cell RNA - CACO-2 [nTPM]":"4.1","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"7.7","Cell RNA - fHDF\/TERT166 [nTPM]":"21.7","Cell RNA - GAMG [nTPM]":"8.5","Cell RNA - HaCaT [nTPM]":"6.4","Cell RNA - HAP1 [nTPM]":"24.7","Cell RNA - HBEC3-KT [nTPM]":"4.7","Cell RNA - HBF TERT88 [nTPM]":"3.2","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"5.4","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"4.6","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"24.7","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"13.5","Cell RNA - hTCEpi [nTPM]":"2.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.4","Cell RNA - hTERT-HME1 [nTPM]":"4.7","Cell RNA - hTERT-RPE1 [nTPM]":"12.9","Cell RNA - HUVEC TERT2 [nTPM]":"3.4","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"4.9","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"2.4","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"37.4","Cell RNA - OE19 [nTPM]":"27.5","Cell RNA - PC-3 [nTPM]":"8.8","Cell RNA - REH [nTPM]":"1.0","Cell RNA - RH-30 [nTPM]":"9.4","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"37.0","Cell RNA - RT4 [nTPM]":"11.8","Cell RNA - SCLC-21H [nTPM]":"14.5","Cell RNA - SH-SY5Y [nTPM]":"27.3","Cell RNA - SiHa [nTPM]":"4.4","Cell RNA - SK-BR-3 [nTPM]":"2.7","Cell RNA - SK-MEL-30 [nTPM]":"46.8","Cell RNA - SuSa [nTPM]":"6.9","Cell RNA - T-47d [nTPM]":"1.7","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"2.8","Cell RNA - U-138 MG [nTPM]":"12.7","Cell RNA - U-2 OS [nTPM]":"3.0","Cell RNA - U-2197 [nTPM]":"10.8","Cell RNA - U-251 MG [nTPM]":"3.9","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"20.9","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"20.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"1.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"29.5","Brain RNA - basal ganglia [nTPM]":"64.4","Brain RNA - cerebellum [nTPM]":"38.6","Brain RNA - cerebral cortex [nTPM]":"46.2","Brain RNA - hippocampal formation [nTPM]":"48.0","Brain RNA - hypothalamus [nTPM]":"34.8","Brain RNA - medulla oblongata [nTPM]":"40.1","Brain RNA - midbrain [nTPM]":"33.2","Brain RNA - pons [nTPM]":"56.3","Brain RNA - spinal cord [nTPM]":"35.3","Brain RNA - thalamus [nTPM]":"37.9","Brain RNA - white matter [nTPM]":"116.2","Single Cell Type RNA - Adipocytes [nTPM]":"11.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"33.7","Single Cell Type RNA - Astrocytes [nTPM]":"189.0","Single Cell Type RNA - B-cells [nTPM]":"2.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"40.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"67.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"40.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"29.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"39.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"82.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"58.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"59.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"101.8","Single Cell Type RNA - Ductal cells [nTPM]":"9.6","Single Cell Type RNA - Early spermatids [nTPM]":"3.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"113.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.3","Single Cell Type RNA - Endothelial cells [nTPM]":"17.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"62.3","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"266.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"22.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"80.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"95.6","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"4.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.0","Single Cell Type RNA - Hepatocytes [nTPM]":"12.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.4","Single Cell Type RNA - Horizontal cells [nTPM]":"111.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"211.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"64.1","Single Cell Type RNA - Ionocytes [nTPM]":"54.9","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"7.7","Single Cell Type RNA - Late spermatids [nTPM]":"2.4","Single Cell Type RNA - Leydig cells [nTPM]":"29.5","Single Cell Type RNA - Macrophages [nTPM]":"2.2","Single Cell Type RNA - Melanocytes [nTPM]":"64.0","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"3.2","Single Cell Type RNA - Muller glia cells [nTPM]":"86.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"237.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1132.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.5","Single Cell Type RNA - Paneth cells [nTPM]":"41.4","Single Cell Type RNA - Peritubular cells [nTPM]":"32.7","Single Cell Type RNA - Plasma cells [nTPM]":"1.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"62.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"106.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.4","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"2.8","Single Cell Type RNA - Theca cells [nTPM]":"8.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"90.8","Single Cell Type RNA - Urothelial cells [nTPM]":"33.7"},{"Gene":"TRIM24","Gene synonym":["hTIF1","RNF82","TIF1","Tif1a"],"Ensembl":"ENSG00000122779","Gene description":"Tripartite motif containing 24","Uniprot":["O15164"],"Chromosome":"7","Position":"138460259-138589996","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["DNA-binding","Repressor","Transferase"],"Disease involvement":["Cancer-related genes","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"146.5","HMC-1":"196.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043495","HPA061717"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA043495":"AB_10962915","HPA061717":"AB_2684592"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.94e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.57e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.5","Tissue RNA - adrenal gland [nTPM]":"25.7","Tissue RNA - amygdala [nTPM]":"6.0","Tissue RNA - appendix [nTPM]":"6.9","Tissue RNA - basal ganglia [nTPM]":"6.8","Tissue RNA - bone marrow [nTPM]":"10.6","Tissue RNA - breast [nTPM]":"9.1","Tissue RNA - cerebellum [nTPM]":"5.8","Tissue RNA - cerebral cortex [nTPM]":"7.0","Tissue RNA - cervix [nTPM]":"6.4","Tissue RNA - choroid plexus [nTPM]":"5.2","Tissue RNA - colon [nTPM]":"8.1","Tissue RNA - duodenum [nTPM]":"10.0","Tissue RNA - endometrium 1 [nTPM]":"8.8","Tissue RNA - epididymis [nTPM]":"8.4","Tissue RNA - esophagus [nTPM]":"9.0","Tissue RNA - fallopian tube [nTPM]":"5.7","Tissue RNA - gallbladder [nTPM]":"5.3","Tissue RNA - heart muscle [nTPM]":"10.4","Tissue RNA - hippocampal formation [nTPM]":"6.0","Tissue RNA - hypothalamus [nTPM]":"7.1","Tissue RNA - kidney [nTPM]":"8.0","Tissue RNA - liver [nTPM]":"23.1","Tissue RNA - lung [nTPM]":"11.4","Tissue RNA - lymph node [nTPM]":"8.0","Tissue RNA - medulla oblongata [nTPM]":"6.8","Tissue RNA - midbrain [nTPM]":"6.4","Tissue RNA - ovary [nTPM]":"30.0","Tissue RNA - pancreas [nTPM]":"10.8","Tissue RNA - parathyroid gland [nTPM]":"14.2","Tissue RNA - pituitary gland [nTPM]":"3.8","Tissue RNA - placenta [nTPM]":"12.3","Tissue RNA - pons [nTPM]":"6.3","Tissue RNA - prostate [nTPM]":"11.7","Tissue RNA - rectum [nTPM]":"9.2","Tissue RNA - retina [nTPM]":"12.2","Tissue RNA - salivary gland [nTPM]":"8.3","Tissue RNA - seminal vesicle [nTPM]":"5.2","Tissue RNA - skeletal muscle [nTPM]":"13.9","Tissue RNA - skin 1 [nTPM]":"8.6","Tissue RNA - small intestine [nTPM]":"9.7","Tissue RNA - smooth muscle [nTPM]":"7.6","Tissue RNA - spinal cord [nTPM]":"6.2","Tissue RNA - spleen [nTPM]":"7.2","Tissue RNA - stomach 1 [nTPM]":"11.6","Tissue RNA - testis [nTPM]":"27.3","Tissue RNA - thalamus [nTPM]":"8.2","Tissue RNA - thymus [nTPM]":"17.3","Tissue RNA - thyroid gland [nTPM]":"9.1","Tissue RNA - tongue [nTPM]":"16.4","Tissue RNA - tonsil [nTPM]":"7.8","Tissue RNA - urinary bladder [nTPM]":"7.5","Tissue RNA - vagina [nTPM]":"6.1","Tissue RNA - white matter [nTPM]":"9.0","Cell RNA - A-431 [nTPM]":"15.0","Cell RNA - A549 [nTPM]":"18.1","Cell RNA - AF22 [nTPM]":"146.5","Cell RNA - AN3-CA [nTPM]":"42.7","Cell RNA - ASC diff [nTPM]":"9.6","Cell RNA - ASC TERT1 [nTPM]":"8.9","Cell RNA - BEWO [nTPM]":"11.4","Cell RNA - BJ [nTPM]":"13.7","Cell RNA - BJ hTERT+ [nTPM]":"14.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.2","Cell RNA - CACO-2 [nTPM]":"28.7","Cell RNA - CAPAN-2 [nTPM]":"13.6","Cell RNA - Daudi [nTPM]":"28.7","Cell RNA - EFO-21 [nTPM]":"13.2","Cell RNA - fHDF\/TERT166 [nTPM]":"13.2","Cell RNA - GAMG [nTPM]":"21.5","Cell RNA - HaCaT [nTPM]":"7.9","Cell RNA - HAP1 [nTPM]":"71.9","Cell RNA - HBEC3-KT [nTPM]":"11.4","Cell RNA - HBF TERT88 [nTPM]":"15.4","Cell RNA - HDLM-2 [nTPM]":"22.1","Cell RNA - HEK 293 [nTPM]":"17.7","Cell RNA - HEL [nTPM]":"63.1","Cell RNA - HeLa [nTPM]":"13.1","Cell RNA - Hep G2 [nTPM]":"88.9","Cell RNA - HHSteC [nTPM]":"13.1","Cell RNA - HL-60 [nTPM]":"49.8","Cell RNA - HMC-1 [nTPM]":"196.8","Cell RNA - HSkMC [nTPM]":"7.9","Cell RNA - hTCEpi [nTPM]":"11.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.8","Cell RNA - hTERT-HME1 [nTPM]":"13.9","Cell RNA - hTERT-RPE1 [nTPM]":"7.3","Cell RNA - HUVEC TERT2 [nTPM]":"25.0","Cell RNA - JURKAT [nTPM]":"15.4","Cell RNA - K-562 [nTPM]":"72.6","Cell RNA - Karpas-707 [nTPM]":"17.1","Cell RNA - LHCN-M2 [nTPM]":"12.7","Cell RNA - MCF7 [nTPM]":"29.2","Cell RNA - MOLT-4 [nTPM]":"85.2","Cell RNA - NB-4 [nTPM]":"44.8","Cell RNA - NTERA-2 [nTPM]":"56.3","Cell RNA - OE19 [nTPM]":"77.6","Cell RNA - PC-3 [nTPM]":"16.0","Cell RNA - REH [nTPM]":"66.5","Cell RNA - RH-30 [nTPM]":"17.3","Cell RNA - RPMI-8226 [nTPM]":"24.2","Cell RNA - RPTEC TERT1 [nTPM]":"23.6","Cell RNA - RT4 [nTPM]":"43.9","Cell RNA - SCLC-21H [nTPM]":"30.3","Cell RNA - SH-SY5Y [nTPM]":"68.8","Cell RNA - SiHa [nTPM]":"25.5","Cell RNA - SK-BR-3 [nTPM]":"22.6","Cell RNA - SK-MEL-30 [nTPM]":"7.5","Cell RNA - SuSa [nTPM]":"50.6","Cell RNA - T-47d [nTPM]":"15.5","Cell RNA - THP-1 [nTPM]":"32.3","Cell RNA - TIME [nTPM]":"10.7","Cell RNA - U-138 MG [nTPM]":"12.1","Cell RNA - U-2 OS [nTPM]":"9.9","Cell RNA - U-2197 [nTPM]":"21.4","Cell RNA - U-251 MG [nTPM]":"19.1","Cell RNA - U-266\/70 [nTPM]":"15.6","Cell RNA - U-266\/84 [nTPM]":"18.2","Cell RNA - U-698 [nTPM]":"47.8","Cell RNA - U-87 MG [nTPM]":"20.1","Cell RNA - U-937 [nTPM]":"32.1","Cell RNA - WM-115 [nTPM]":"18.0","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"1.0","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"6.0","Brain RNA - basal ganglia [nTPM]":"6.8","Brain RNA - cerebellum [nTPM]":"5.8","Brain RNA - cerebral cortex [nTPM]":"7.0","Brain RNA - hippocampal formation [nTPM]":"6.0","Brain RNA - hypothalamus [nTPM]":"7.1","Brain RNA - medulla oblongata [nTPM]":"6.8","Brain RNA - midbrain [nTPM]":"6.4","Brain RNA - pons [nTPM]":"6.3","Brain RNA - spinal cord [nTPM]":"6.2","Brain RNA - thalamus [nTPM]":"8.2","Brain RNA - white matter [nTPM]":"9.0","Single Cell Type RNA - Adipocytes [nTPM]":"29.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"46.9","Single Cell Type RNA - Astrocytes [nTPM]":"26.1","Single Cell Type RNA - B-cells [nTPM]":"9.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"13.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"39.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"18.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"28.4","Single Cell Type RNA - dendritic cells [nTPM]":"14.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.1","Single Cell Type RNA - Early spermatids [nTPM]":"70.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.9","Single Cell Type RNA - Endothelial cells [nTPM]":"18.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.1","Single Cell Type RNA - Erythroid cells [nTPM]":"31.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"27.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.2","Single Cell Type RNA - Fibroblasts [nTPM]":"16.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.2","Single Cell Type RNA - granulocytes [nTPM]":"40.4","Single Cell Type RNA - Granulosa cells [nTPM]":"85.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.3","Single Cell Type RNA - Hepatocytes [nTPM]":"31.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.3","Single Cell Type RNA - Horizontal cells [nTPM]":"40.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"46.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.9","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"9.5","Single Cell Type RNA - Langerhans cells [nTPM]":"14.9","Single Cell Type RNA - Late spermatids [nTPM]":"38.7","Single Cell Type RNA - Leydig cells [nTPM]":"14.0","Single Cell Type RNA - Macrophages [nTPM]":"13.8","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"12.2","Single Cell Type RNA - Muller glia cells [nTPM]":"23.3","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"64.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"67.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.5","Single Cell Type RNA - Paneth cells [nTPM]":"9.5","Single Cell Type RNA - Peritubular cells [nTPM]":"16.1","Single Cell Type RNA - Plasma cells [nTPM]":"13.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"22.4","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.6","Single Cell Type RNA - Spermatocytes [nTPM]":"72.8","Single Cell Type RNA - Spermatogonia [nTPM]":"14.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.2","Single Cell Type RNA - T-cells [nTPM]":"15.8","Single Cell Type RNA - Theca cells [nTPM]":"34.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.4","Single Cell Type RNA - Urothelial cells [nTPM]":"12.8"},{"Gene":"TRIM27","Gene synonym":["RFP","RNF76"],"Ensembl":"ENSG00000204713","Gene description":"Tripartite motif containing 27","Uniprot":["P14373"],"Chromosome":"6","Position":"28903002-28923988","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation","Transport","Ubl conjugation pathway"],"Molecular function":["DNA-binding","Repressor","Transferase"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RPMI-8226":"49.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048684","HPA053408"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA048684":"AB_2680493","HPA053408":"AB_2682139"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.50e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.71e-4"},"Tissue RNA - adipose tissue [nTPM]":"23.8","Tissue RNA - adrenal gland [nTPM]":"28.1","Tissue RNA - amygdala [nTPM]":"1.8","Tissue RNA - appendix [nTPM]":"7.2","Tissue RNA - basal ganglia [nTPM]":"1.7","Tissue RNA - bone marrow [nTPM]":"1.1","Tissue RNA - breast [nTPM]":"23.3","Tissue RNA - cerebellum [nTPM]":"1.1","Tissue RNA - cerebral cortex [nTPM]":"2.6","Tissue RNA - cervix [nTPM]":"33.0","Tissue RNA - choroid plexus [nTPM]":"2.2","Tissue RNA - colon [nTPM]":"23.0","Tissue RNA - duodenum [nTPM]":"8.7","Tissue RNA - endometrium 1 [nTPM]":"24.5","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"20.5","Tissue RNA - fallopian tube [nTPM]":"31.0","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"24.3","Tissue RNA - hippocampal formation [nTPM]":"1.6","Tissue RNA - hypothalamus [nTPM]":"1.3","Tissue RNA - kidney [nTPM]":"32.7","Tissue RNA - liver [nTPM]":"59.5","Tissue RNA - lung [nTPM]":"26.8","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"2.2","Tissue RNA - midbrain [nTPM]":"2.1","Tissue RNA - ovary [nTPM]":"30.8","Tissue RNA - pancreas [nTPM]":"53.0","Tissue RNA - parathyroid gland [nTPM]":"0.6","Tissue RNA - pituitary gland [nTPM]":"33.8","Tissue RNA - placenta [nTPM]":"4.5","Tissue RNA - pons [nTPM]":"1.8","Tissue RNA - prostate [nTPM]":"35.1","Tissue RNA - rectum [nTPM]":"0.6","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"25.8","Tissue RNA - seminal vesicle [nTPM]":"6.5","Tissue RNA - skeletal muscle [nTPM]":"21.2","Tissue RNA - skin 1 [nTPM]":"17.6","Tissue RNA - small intestine [nTPM]":"26.8","Tissue RNA - smooth muscle [nTPM]":"2.3","Tissue RNA - spinal cord [nTPM]":"1.5","Tissue RNA - spleen [nTPM]":"45.8","Tissue RNA - stomach 1 [nTPM]":"27.3","Tissue RNA - testis [nTPM]":"14.4","Tissue RNA - thalamus [nTPM]":"2.0","Tissue RNA - thymus [nTPM]":"0.9","Tissue RNA - thyroid gland [nTPM]":"26.3","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"1.0","Tissue RNA - urinary bladder [nTPM]":"28.7","Tissue RNA - vagina [nTPM]":"22.6","Tissue RNA - white matter [nTPM]":"2.0","Cell RNA - A-431 [nTPM]":"2.4","Cell RNA - A549 [nTPM]":"8.2","Cell RNA - AF22 [nTPM]":"1.2","Cell RNA - AN3-CA [nTPM]":"21.7","Cell RNA - ASC diff [nTPM]":"2.8","Cell RNA - ASC TERT1 [nTPM]":"6.2","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"16.1","Cell RNA - BJ hTERT+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.2","Cell RNA - CACO-2 [nTPM]":"6.1","Cell RNA - CAPAN-2 [nTPM]":"1.7","Cell RNA - Daudi [nTPM]":"1.6","Cell RNA - EFO-21 [nTPM]":"1.1","Cell RNA - fHDF\/TERT166 [nTPM]":"4.8","Cell RNA - GAMG [nTPM]":"1.3","Cell RNA - HaCaT [nTPM]":"17.5","Cell RNA - HAP1 [nTPM]":"4.0","Cell RNA - HBEC3-KT [nTPM]":"9.2","Cell RNA - HBF TERT88 [nTPM]":"0.5","Cell RNA - HDLM-2 [nTPM]":"1.3","Cell RNA - HEK 293 [nTPM]":"2.6","Cell RNA - HEL [nTPM]":"20.3","Cell RNA - HeLa [nTPM]":"2.5","Cell RNA - Hep G2 [nTPM]":"9.3","Cell RNA - HHSteC [nTPM]":"4.3","Cell RNA - HL-60 [nTPM]":"2.0","Cell RNA - HMC-1 [nTPM]":"5.7","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"1.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.1","Cell RNA - hTERT-HME1 [nTPM]":"1.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.6","Cell RNA - HUVEC TERT2 [nTPM]":"4.5","Cell RNA - JURKAT [nTPM]":"5.8","Cell RNA - K-562 [nTPM]":"2.1","Cell RNA - Karpas-707 [nTPM]":"12.1","Cell RNA - LHCN-M2 [nTPM]":"1.3","Cell RNA - MCF7 [nTPM]":"4.9","Cell RNA - MOLT-4 [nTPM]":"11.1","Cell RNA - NB-4 [nTPM]":"0.9","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"3.4","Cell RNA - PC-3 [nTPM]":"13.5","Cell RNA - REH [nTPM]":"20.1","Cell RNA - RH-30 [nTPM]":"4.6","Cell RNA - RPMI-8226 [nTPM]":"49.7","Cell RNA - RPTEC TERT1 [nTPM]":"3.9","Cell RNA - RT4 [nTPM]":"2.3","Cell RNA - SCLC-21H [nTPM]":"4.9","Cell RNA - SH-SY5Y [nTPM]":"18.7","Cell RNA - SiHa [nTPM]":"19.9","Cell RNA - SK-BR-3 [nTPM]":"11.6","Cell RNA - SK-MEL-30 [nTPM]":"4.1","Cell RNA - SuSa [nTPM]":"0.6","Cell RNA - T-47d [nTPM]":"11.6","Cell RNA - THP-1 [nTPM]":"12.2","Cell RNA - TIME [nTPM]":"13.1","Cell RNA - U-138 MG [nTPM]":"6.3","Cell RNA - U-2 OS [nTPM]":"9.3","Cell RNA - U-2197 [nTPM]":"14.7","Cell RNA - U-251 MG [nTPM]":"5.1","Cell RNA - U-266\/70 [nTPM]":"31.7","Cell RNA - U-266\/84 [nTPM]":"2.7","Cell RNA - U-698 [nTPM]":"17.9","Cell RNA - U-87 MG [nTPM]":"6.8","Cell RNA - U-937 [nTPM]":"24.8","Cell RNA - WM-115 [nTPM]":"20.0","Blood RNA - basophil [nTPM]":"5.2","Blood RNA - classical monocyte [nTPM]":"4.4","Blood RNA - eosinophil [nTPM]":"2.5","Blood RNA - gdT-cell [nTPM]":"7.0","Blood RNA - intermediate monocyte [nTPM]":"12.5","Blood RNA - MAIT T-cell [nTPM]":"11.3","Blood RNA - memory B-cell [nTPM]":"7.0","Blood RNA - memory CD4 T-cell [nTPM]":"10.6","Blood RNA - memory CD8 T-cell [nTPM]":"5.5","Blood RNA - myeloid DC [nTPM]":"8.5","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"4.1","Blood RNA - naive CD8 T-cell [nTPM]":"7.6","Blood RNA - neutrophil [nTPM]":"2.7","Blood RNA - NK-cell [nTPM]":"6.4","Blood RNA - non-classical monocyte [nTPM]":"7.0","Blood RNA - plasmacytoid DC [nTPM]":"5.6","Blood RNA - T-reg [nTPM]":"5.2","Blood RNA - total PBMC [nTPM]":"9.9","Brain RNA - amygdala [nTPM]":"1.8","Brain RNA - basal ganglia [nTPM]":"1.7","Brain RNA - cerebellum [nTPM]":"1.1","Brain RNA - cerebral cortex [nTPM]":"2.6","Brain RNA - hippocampal formation [nTPM]":"1.6","Brain RNA - hypothalamus [nTPM]":"1.3","Brain RNA - medulla oblongata [nTPM]":"2.2","Brain RNA - midbrain [nTPM]":"2.1","Brain RNA - pons [nTPM]":"1.8","Brain RNA - spinal cord [nTPM]":"1.5","Brain RNA - thalamus [nTPM]":"2.0","Brain RNA - white matter [nTPM]":"2.0","Single Cell Type RNA - Adipocytes [nTPM]":"21.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"24.8","Single Cell Type RNA - Astrocytes [nTPM]":"11.8","Single Cell Type RNA - B-cells [nTPM]":"32.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"28.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"41.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"27.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"33.6","Single Cell Type RNA - Bipolar cells [nTPM]":"11.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"32.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"24.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"46.4","Single Cell Type RNA - dendritic cells [nTPM]":"25.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"39.5","Single Cell Type RNA - Early spermatids [nTPM]":"12.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"27.0","Single Cell Type RNA - Endothelial cells [nTPM]":"32.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"27.6","Single Cell Type RNA - Erythroid cells [nTPM]":"24.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"43.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"55.5","Single Cell Type RNA - Fibroblasts [nTPM]":"25.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"26.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"27.2","Single Cell Type RNA - granulocytes [nTPM]":"21.5","Single Cell Type RNA - Granulosa cells [nTPM]":"36.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"27.8","Single Cell Type RNA - Hepatocytes [nTPM]":"42.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"41.1","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"38.5","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"28.3","Single Cell Type RNA - Langerhans cells [nTPM]":"23.5","Single Cell Type RNA - Late spermatids [nTPM]":"6.8","Single Cell Type RNA - Leydig cells [nTPM]":"23.9","Single Cell Type RNA - Macrophages [nTPM]":"29.0","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"46.5","Single Cell Type RNA - Muller glia cells [nTPM]":"10.4","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"48.9","Single Cell Type RNA - Paneth cells [nTPM]":"18.7","Single Cell Type RNA - Peritubular cells [nTPM]":"18.4","Single Cell Type RNA - Plasma cells [nTPM]":"51.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"53.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"19.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"27.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.6","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"31.0","Single Cell Type RNA - Spermatocytes [nTPM]":"8.0","Single Cell Type RNA - Spermatogonia [nTPM]":"16.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"19.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"45.6","Single Cell Type RNA - T-cells [nTPM]":"28.9","Single Cell Type RNA - Theca cells [nTPM]":"43.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"28.3","Single Cell Type RNA - Urothelial cells [nTPM]":"30.9"},{"Gene":"TRIM32","Gene synonym":["BBS11","HT2A","LGMD2H","TATIP"],"Ensembl":"ENSG00000119401","Gene description":"Tripartite motif containing 32","Uniprot":["Q13049"],"Chromosome":"9","Position":"116687305-116701300","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Bardet-Biedl syndrome","Ciliopathy","Disease variant","Limb-girdle muscular dystrophy","Mental retardation","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050060"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Intermediate filaments"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Intermediate filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA050060":"AB_2681000"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.53e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.72e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.77e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.7","Tissue RNA - adrenal gland [nTPM]":"7.2","Tissue RNA - amygdala [nTPM]":"4.6","Tissue RNA - appendix [nTPM]":"5.4","Tissue RNA - basal ganglia [nTPM]":"4.5","Tissue RNA - bone marrow [nTPM]":"1.0","Tissue RNA - breast [nTPM]":"6.8","Tissue RNA - cerebellum [nTPM]":"16.4","Tissue RNA - cerebral cortex [nTPM]":"5.4","Tissue RNA - cervix [nTPM]":"10.1","Tissue RNA - choroid plexus [nTPM]":"15.2","Tissue RNA - colon [nTPM]":"6.0","Tissue RNA - duodenum [nTPM]":"5.9","Tissue RNA - endometrium 1 [nTPM]":"10.6","Tissue RNA - epididymis [nTPM]":"6.5","Tissue RNA - esophagus [nTPM]":"7.4","Tissue RNA - fallopian tube [nTPM]":"13.1","Tissue RNA - gallbladder [nTPM]":"6.4","Tissue RNA - heart muscle [nTPM]":"7.9","Tissue RNA - hippocampal formation [nTPM]":"4.7","Tissue RNA - hypothalamus [nTPM]":"6.1","Tissue RNA - kidney [nTPM]":"5.2","Tissue RNA - liver [nTPM]":"3.8","Tissue RNA - lung [nTPM]":"5.5","Tissue RNA - lymph node [nTPM]":"8.1","Tissue RNA - medulla oblongata [nTPM]":"3.6","Tissue RNA - midbrain [nTPM]":"2.8","Tissue RNA - ovary [nTPM]":"10.1","Tissue RNA - pancreas [nTPM]":"6.2","Tissue RNA - parathyroid gland [nTPM]":"8.6","Tissue RNA - pituitary gland [nTPM]":"3.5","Tissue RNA - placenta [nTPM]":"6.1","Tissue RNA - pons [nTPM]":"3.9","Tissue RNA - prostate [nTPM]":"6.9","Tissue RNA - rectum [nTPM]":"6.2","Tissue RNA - retina [nTPM]":"7.2","Tissue RNA - salivary gland [nTPM]":"5.2","Tissue RNA - seminal vesicle [nTPM]":"7.3","Tissue RNA - skeletal muscle [nTPM]":"18.6","Tissue RNA - skin 1 [nTPM]":"4.6","Tissue RNA - small intestine [nTPM]":"7.2","Tissue RNA - smooth muscle [nTPM]":"10.7","Tissue RNA - spinal cord [nTPM]":"2.1","Tissue RNA - spleen [nTPM]":"6.2","Tissue RNA - stomach 1 [nTPM]":"5.4","Tissue RNA - testis [nTPM]":"5.2","Tissue RNA - thalamus [nTPM]":"4.5","Tissue RNA - thymus [nTPM]":"7.5","Tissue RNA - thyroid gland [nTPM]":"6.3","Tissue RNA - tongue [nTPM]":"12.5","Tissue RNA - tonsil [nTPM]":"7.4","Tissue RNA - urinary bladder [nTPM]":"7.6","Tissue RNA - vagina [nTPM]":"5.7","Tissue RNA - white matter [nTPM]":"3.4","Cell RNA - A-431 [nTPM]":"10.9","Cell RNA - A549 [nTPM]":"24.5","Cell RNA - AF22 [nTPM]":"14.3","Cell RNA - AN3-CA [nTPM]":"15.7","Cell RNA - ASC diff [nTPM]":"28.3","Cell RNA - ASC TERT1 [nTPM]":"20.1","Cell RNA - BEWO [nTPM]":"10.8","Cell RNA - BJ [nTPM]":"19.9","Cell RNA - BJ hTERT+ [nTPM]":"21.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"22.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"18.4","Cell RNA - CACO-2 [nTPM]":"16.4","Cell RNA - CAPAN-2 [nTPM]":"11.7","Cell RNA - Daudi [nTPM]":"11.3","Cell RNA - EFO-21 [nTPM]":"8.6","Cell RNA - fHDF\/TERT166 [nTPM]":"30.7","Cell RNA - GAMG [nTPM]":"16.5","Cell RNA - HaCaT [nTPM]":"22.8","Cell RNA - HAP1 [nTPM]":"17.5","Cell RNA - HBEC3-KT [nTPM]":"22.4","Cell RNA - HBF TERT88 [nTPM]":"20.0","Cell RNA - HDLM-2 [nTPM]":"9.9","Cell RNA - HEK 293 [nTPM]":"8.5","Cell RNA - HEL [nTPM]":"6.1","Cell RNA - HeLa [nTPM]":"15.4","Cell RNA - Hep G2 [nTPM]":"10.2","Cell RNA - HHSteC [nTPM]":"14.7","Cell RNA - HL-60 [nTPM]":"4.1","Cell RNA - HMC-1 [nTPM]":"19.1","Cell RNA - HSkMC [nTPM]":"17.4","Cell RNA - hTCEpi [nTPM]":"19.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.0","Cell RNA - hTERT-HME1 [nTPM]":"12.3","Cell RNA - hTERT-RPE1 [nTPM]":"24.4","Cell RNA - HUVEC TERT2 [nTPM]":"14.6","Cell RNA - JURKAT [nTPM]":"12.4","Cell RNA - K-562 [nTPM]":"8.6","Cell RNA - Karpas-707 [nTPM]":"9.3","Cell RNA - LHCN-M2 [nTPM]":"26.3","Cell RNA - MCF7 [nTPM]":"13.9","Cell RNA - MOLT-4 [nTPM]":"11.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"13.0","Cell RNA - OE19 [nTPM]":"26.2","Cell RNA - PC-3 [nTPM]":"14.6","Cell RNA - REH [nTPM]":"12.7","Cell RNA - RH-30 [nTPM]":"38.2","Cell RNA - RPMI-8226 [nTPM]":"7.4","Cell RNA - RPTEC TERT1 [nTPM]":"9.0","Cell RNA - RT4 [nTPM]":"25.1","Cell RNA - SCLC-21H [nTPM]":"14.2","Cell RNA - SH-SY5Y [nTPM]":"7.2","Cell RNA - SiHa [nTPM]":"15.7","Cell RNA - SK-BR-3 [nTPM]":"10.8","Cell RNA - SK-MEL-30 [nTPM]":"11.4","Cell RNA - SuSa [nTPM]":"14.3","Cell RNA - T-47d [nTPM]":"29.8","Cell RNA - THP-1 [nTPM]":"4.0","Cell RNA - TIME [nTPM]":"18.2","Cell RNA - U-138 MG [nTPM]":"20.4","Cell RNA - U-2 OS [nTPM]":"16.2","Cell RNA - U-2197 [nTPM]":"15.3","Cell RNA - U-251 MG [nTPM]":"15.2","Cell RNA - U-266\/70 [nTPM]":"15.1","Cell RNA - U-266\/84 [nTPM]":"4.3","Cell RNA - U-698 [nTPM]":"17.7","Cell RNA - U-87 MG [nTPM]":"17.0","Cell RNA - U-937 [nTPM]":"2.7","Cell RNA - WM-115 [nTPM]":"20.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.7","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"10.9","Blood RNA - intermediate monocyte [nTPM]":"3.3","Blood RNA - MAIT T-cell [nTPM]":"8.4","Blood RNA - memory B-cell [nTPM]":"7.3","Blood RNA - memory CD4 T-cell [nTPM]":"9.5","Blood RNA - memory CD8 T-cell [nTPM]":"8.7","Blood RNA - myeloid DC [nTPM]":"2.3","Blood RNA - naive B-cell [nTPM]":"5.1","Blood RNA - naive CD4 T-cell [nTPM]":"9.6","Blood RNA - naive CD8 T-cell [nTPM]":"9.8","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"7.0","Blood RNA - non-classical monocyte [nTPM]":"3.0","Blood RNA - plasmacytoid DC [nTPM]":"4.3","Blood RNA - T-reg [nTPM]":"20.9","Blood RNA - total PBMC [nTPM]":"6.0","Brain RNA - amygdala [nTPM]":"4.6","Brain RNA - basal ganglia [nTPM]":"4.5","Brain RNA - cerebellum [nTPM]":"16.4","Brain RNA - cerebral cortex [nTPM]":"5.4","Brain RNA - hippocampal formation [nTPM]":"4.7","Brain RNA - hypothalamus [nTPM]":"6.1","Brain RNA - medulla oblongata [nTPM]":"3.6","Brain RNA - midbrain [nTPM]":"2.8","Brain RNA - pons [nTPM]":"3.9","Brain RNA - spinal cord [nTPM]":"2.1","Brain RNA - thalamus [nTPM]":"4.5","Brain RNA - white matter [nTPM]":"3.4","Single Cell Type RNA - Adipocytes [nTPM]":"2.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"4.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"11.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"7.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.7","Single Cell Type RNA - dendritic cells [nTPM]":"2.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.5","Single Cell Type RNA - Early spermatids [nTPM]":"3.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.7","Single Cell Type RNA - Endothelial cells [nTPM]":"3.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.6","Single Cell Type RNA - Fibroblasts [nTPM]":"6.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.3","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"4.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.9","Single Cell Type RNA - Hepatocytes [nTPM]":"4.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.2","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.0","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"2.4","Single Cell Type RNA - Langerhans cells [nTPM]":"4.7","Single Cell Type RNA - Late spermatids [nTPM]":"2.1","Single Cell Type RNA - Leydig cells [nTPM]":"5.3","Single Cell Type RNA - Macrophages [nTPM]":"2.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.8","Single Cell Type RNA - Muller glia cells [nTPM]":"4.0","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.0","Single Cell Type RNA - Paneth cells [nTPM]":"2.6","Single Cell Type RNA - Peritubular cells [nTPM]":"12.0","Single Cell Type RNA - Plasma cells [nTPM]":"3.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.6","Single Cell Type RNA - Spermatocytes [nTPM]":"17.7","Single Cell Type RNA - Spermatogonia [nTPM]":"13.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.4","Single Cell Type RNA - T-cells [nTPM]":"4.7","Single Cell Type RNA - Theca cells [nTPM]":"5.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.3","Single Cell Type RNA - Urothelial cells [nTPM]":"4.8"},{"Gene":"TRIM33","Gene synonym":["FLJ11429","KIAA1113","PTC7","RFG7","TF1G","TIF1G","TIF1GAMMA","TIFGAMMA"],"Ensembl":"ENSG00000197323","Gene description":"Tripartite motif containing 33","Uniprot":["Q9UPN9"],"Chromosome":"1","Position":"114392790-114511203","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["DNA-binding","Repressor","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"237.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"13.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"115.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004345"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA004345":"AB_1858287"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.20e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.93e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.3","Tissue RNA - adrenal gland [nTPM]":"8.1","Tissue RNA - amygdala [nTPM]":"10.1","Tissue RNA - appendix [nTPM]":"10.7","Tissue RNA - basal ganglia [nTPM]":"11.3","Tissue RNA - bone marrow [nTPM]":"25.4","Tissue RNA - breast [nTPM]":"13.5","Tissue RNA - cerebellum [nTPM]":"18.3","Tissue RNA - cerebral cortex [nTPM]":"16.9","Tissue RNA - cervix [nTPM]":"12.5","Tissue RNA - choroid plexus [nTPM]":"8.2","Tissue RNA - colon [nTPM]":"9.5","Tissue RNA - duodenum [nTPM]":"8.8","Tissue RNA - endometrium 1 [nTPM]":"15.2","Tissue RNA - epididymis [nTPM]":"29.8","Tissue RNA - esophagus [nTPM]":"11.7","Tissue RNA - fallopian tube [nTPM]":"9.1","Tissue RNA - gallbladder [nTPM]":"10.9","Tissue RNA - heart muscle [nTPM]":"8.9","Tissue RNA - hippocampal formation [nTPM]":"11.5","Tissue RNA - hypothalamus [nTPM]":"9.9","Tissue RNA - kidney [nTPM]":"13.5","Tissue RNA - liver [nTPM]":"12.2","Tissue RNA - lung [nTPM]":"10.9","Tissue RNA - lymph node [nTPM]":"13.3","Tissue RNA - medulla oblongata [nTPM]":"8.0","Tissue RNA - midbrain [nTPM]":"9.1","Tissue RNA - ovary [nTPM]":"14.4","Tissue RNA - pancreas [nTPM]":"12.2","Tissue RNA - parathyroid gland [nTPM]":"15.3","Tissue RNA - pituitary gland [nTPM]":"7.3","Tissue RNA - placenta [nTPM]":"16.0","Tissue RNA - pons [nTPM]":"8.2","Tissue RNA - prostate [nTPM]":"12.6","Tissue RNA - rectum [nTPM]":"10.1","Tissue RNA - retina [nTPM]":"18.8","Tissue RNA - salivary gland [nTPM]":"10.7","Tissue RNA - seminal vesicle [nTPM]":"11.0","Tissue RNA - skeletal muscle [nTPM]":"8.8","Tissue RNA - skin 1 [nTPM]":"14.8","Tissue RNA - small intestine [nTPM]":"8.9","Tissue RNA - smooth muscle [nTPM]":"11.8","Tissue RNA - spinal cord [nTPM]":"8.1","Tissue RNA - spleen [nTPM]":"12.7","Tissue RNA - stomach 1 [nTPM]":"11.2","Tissue RNA - testis [nTPM]":"25.3","Tissue RNA - thalamus [nTPM]":"9.5","Tissue RNA - thymus [nTPM]":"17.8","Tissue RNA - thyroid gland [nTPM]":"14.2","Tissue RNA - tongue [nTPM]":"10.7","Tissue RNA - tonsil [nTPM]":"12.8","Tissue RNA - urinary bladder [nTPM]":"11.5","Tissue RNA - vagina [nTPM]":"9.8","Tissue RNA - white matter [nTPM]":"11.3","Cell RNA - A-431 [nTPM]":"30.9","Cell RNA - A549 [nTPM]":"16.3","Cell RNA - AF22 [nTPM]":"30.1","Cell RNA - AN3-CA [nTPM]":"22.6","Cell RNA - ASC diff [nTPM]":"12.5","Cell RNA - ASC TERT1 [nTPM]":"13.1","Cell RNA - BEWO [nTPM]":"51.0","Cell RNA - BJ [nTPM]":"15.4","Cell RNA - BJ hTERT+ [nTPM]":"16.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"22.1","Cell RNA - CACO-2 [nTPM]":"18.5","Cell RNA - CAPAN-2 [nTPM]":"12.8","Cell RNA - Daudi [nTPM]":"32.8","Cell RNA - EFO-21 [nTPM]":"15.5","Cell RNA - fHDF\/TERT166 [nTPM]":"18.1","Cell RNA - GAMG [nTPM]":"13.6","Cell RNA - HaCaT [nTPM]":"17.4","Cell RNA - HAP1 [nTPM]":"27.6","Cell RNA - HBEC3-KT [nTPM]":"18.0","Cell RNA - HBF TERT88 [nTPM]":"28.6","Cell RNA - HDLM-2 [nTPM]":"24.9","Cell RNA - HEK 293 [nTPM]":"16.4","Cell RNA - HEL [nTPM]":"31.6","Cell RNA - HeLa [nTPM]":"21.7","Cell RNA - Hep G2 [nTPM]":"21.6","Cell RNA - HHSteC [nTPM]":"13.8","Cell RNA - HL-60 [nTPM]":"40.3","Cell RNA - HMC-1 [nTPM]":"25.3","Cell RNA - HSkMC [nTPM]":"12.5","Cell RNA - hTCEpi [nTPM]":"12.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"24.9","Cell RNA - hTERT-HME1 [nTPM]":"25.2","Cell RNA - hTERT-RPE1 [nTPM]":"16.0","Cell RNA - HUVEC TERT2 [nTPM]":"17.8","Cell RNA - JURKAT [nTPM]":"27.3","Cell RNA - K-562 [nTPM]":"40.1","Cell RNA - Karpas-707 [nTPM]":"22.5","Cell RNA - LHCN-M2 [nTPM]":"20.2","Cell RNA - MCF7 [nTPM]":"115.4","Cell RNA - MOLT-4 [nTPM]":"40.9","Cell RNA - NB-4 [nTPM]":"17.0","Cell RNA - NTERA-2 [nTPM]":"40.7","Cell RNA - OE19 [nTPM]":"11.7","Cell RNA - PC-3 [nTPM]":"16.3","Cell RNA - REH [nTPM]":"34.8","Cell RNA - RH-30 [nTPM]":"45.9","Cell RNA - RPMI-8226 [nTPM]":"10.8","Cell RNA - RPTEC TERT1 [nTPM]":"14.9","Cell RNA - RT4 [nTPM]":"47.7","Cell RNA - SCLC-21H [nTPM]":"20.8","Cell RNA - SH-SY5Y [nTPM]":"21.9","Cell RNA - SiHa [nTPM]":"29.2","Cell RNA - SK-BR-3 [nTPM]":"34.7","Cell RNA - SK-MEL-30 [nTPM]":"27.4","Cell RNA - SuSa [nTPM]":"19.3","Cell RNA - T-47d [nTPM]":"15.8","Cell RNA - THP-1 [nTPM]":"21.7","Cell RNA - TIME [nTPM]":"20.1","Cell RNA - U-138 MG [nTPM]":"14.5","Cell RNA - U-2 OS [nTPM]":"23.4","Cell RNA - U-2197 [nTPM]":"33.8","Cell RNA - U-251 MG [nTPM]":"21.7","Cell RNA - U-266\/70 [nTPM]":"15.7","Cell RNA - U-266\/84 [nTPM]":"15.6","Cell RNA - U-698 [nTPM]":"33.4","Cell RNA - U-87 MG [nTPM]":"20.4","Cell RNA - U-937 [nTPM]":"23.0","Cell RNA - WM-115 [nTPM]":"42.0","Blood RNA - basophil [nTPM]":"13.2","Blood RNA - classical monocyte [nTPM]":"1.2","Blood RNA - eosinophil [nTPM]":"6.1","Blood RNA - gdT-cell [nTPM]":"2.5","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"2.2","Blood RNA - memory B-cell [nTPM]":"3.0","Blood RNA - memory CD4 T-cell [nTPM]":"2.6","Blood RNA - memory CD8 T-cell [nTPM]":"2.7","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"1.4","Blood RNA - naive CD4 T-cell [nTPM]":"2.0","Blood RNA - naive CD8 T-cell [nTPM]":"3.1","Blood RNA - neutrophil [nTPM]":"3.6","Blood RNA - NK-cell [nTPM]":"4.1","Blood RNA - non-classical monocyte [nTPM]":"2.4","Blood RNA - plasmacytoid DC [nTPM]":"3.0","Blood RNA - T-reg [nTPM]":"1.6","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"10.1","Brain RNA - basal ganglia [nTPM]":"11.3","Brain RNA - cerebellum [nTPM]":"18.3","Brain RNA - cerebral cortex [nTPM]":"16.9","Brain RNA - hippocampal formation [nTPM]":"11.5","Brain RNA - hypothalamus [nTPM]":"9.9","Brain RNA - medulla oblongata [nTPM]":"8.0","Brain RNA - midbrain [nTPM]":"9.1","Brain RNA - pons [nTPM]":"8.2","Brain RNA - spinal cord [nTPM]":"8.1","Brain RNA - thalamus [nTPM]":"9.5","Brain RNA - white matter [nTPM]":"11.3","Single Cell Type RNA - Adipocytes [nTPM]":"31.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"33.3","Single Cell Type RNA - Astrocytes [nTPM]":"70.5","Single Cell Type RNA - B-cells [nTPM]":"35.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"52.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"28.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"28.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.6","Single Cell Type RNA - Bipolar cells [nTPM]":"75.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"35.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"29.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"32.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"55.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"98.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"64.9","Single Cell Type RNA - dendritic cells [nTPM]":"53.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"33.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"21.0","Single Cell Type RNA - Early spermatids [nTPM]":"237.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"50.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"37.5","Single Cell Type RNA - Endothelial cells [nTPM]":"33.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"52.1","Single Cell Type RNA - Erythroid cells [nTPM]":"37.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"120.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"34.0","Single Cell Type RNA - Fibroblasts [nTPM]":"28.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"30.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"90.0","Single Cell Type RNA - granulocytes [nTPM]":"37.4","Single Cell Type RNA - Granulosa cells [nTPM]":"55.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"40.7","Single Cell Type RNA - Hepatocytes [nTPM]":"44.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"29.6","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"108.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"30.4","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"50.3","Single Cell Type RNA - Langerhans cells [nTPM]":"47.9","Single Cell Type RNA - Late spermatids [nTPM]":"97.9","Single Cell Type RNA - Leydig cells [nTPM]":"49.0","Single Cell Type RNA - Macrophages [nTPM]":"37.2","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"79.6","Single Cell Type RNA - monocytes [nTPM]":"42.9","Single Cell Type RNA - Muller glia cells [nTPM]":"31.5","Single Cell Type RNA - NK-cells [nTPM]":"54.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"116.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"101.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"31.4","Single Cell Type RNA - Paneth cells [nTPM]":"34.9","Single Cell Type RNA - Peritubular cells [nTPM]":"36.9","Single Cell Type RNA - Plasma cells [nTPM]":"31.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"47.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"26.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"31.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"58.3","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"38.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.5","Single Cell Type RNA - Spermatocytes [nTPM]":"60.0","Single Cell Type RNA - Spermatogonia [nTPM]":"31.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"31.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"55.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"87.7","Single Cell Type RNA - T-cells [nTPM]":"42.8","Single Cell Type RNA - Theca cells [nTPM]":"48.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"31.2","Single Cell Type RNA - Urothelial cells [nTPM]":"55.3"},{"Gene":"TRIM36","Gene synonym":["HAPRIN","RBCC728","RNF98"],"Ensembl":"ENSG00000152503","Gene description":"Tripartite motif containing 36","Uniprot":["Q9NQ86"],"Chromosome":"5","Position":"115124762-115180546","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"retina":"44.2","testis":"174.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"26","RNA single cell type specific nTPM":{"Early spermatids":"2120.7","Late spermatids":"4980.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"9.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"5.8","non-classical monocyte":"6.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"48","RNA blood lineage specific nTPM":{"dendritic cells":"5.8","granulocytes":"3.2","monocytes":"6.5"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RH-30":"24.5","SCLC-21H":"28.3","SH-SY5Y":"19.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA061321"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA061321":"AB_2684479"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"1.3","Tissue RNA - amygdala [nTPM]":"13.2","Tissue RNA - appendix [nTPM]":"1.6","Tissue RNA - basal ganglia [nTPM]":"16.7","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"4.4","Tissue RNA - cerebellum [nTPM]":"3.9","Tissue RNA - cerebral cortex [nTPM]":"14.2","Tissue RNA - cervix [nTPM]":"2.4","Tissue RNA - choroid plexus [nTPM]":"8.7","Tissue RNA - colon [nTPM]":"7.5","Tissue RNA - duodenum [nTPM]":"14.1","Tissue RNA - endometrium 1 [nTPM]":"0.9","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"2.2","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"16.1","Tissue RNA - hypothalamus [nTPM]":"15.7","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"1.8","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"17.0","Tissue RNA - midbrain [nTPM]":"10.5","Tissue RNA - ovary [nTPM]":"4.7","Tissue RNA - pancreas [nTPM]":"1.6","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"13.4","Tissue RNA - placenta [nTPM]":"1.1","Tissue RNA - pons [nTPM]":"16.1","Tissue RNA - prostate [nTPM]":"10.0","Tissue RNA - rectum [nTPM]":"7.5","Tissue RNA - retina [nTPM]":"44.2","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"13.8","Tissue RNA - smooth muscle [nTPM]":"0.8","Tissue RNA - spinal cord [nTPM]":"10.2","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"4.6","Tissue RNA - testis [nTPM]":"174.3","Tissue RNA - thalamus [nTPM]":"12.7","Tissue RNA - thymus [nTPM]":"0.7","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"1.3","Tissue RNA - white matter [nTPM]":"20.0","Cell RNA - A-431 [nTPM]":"3.6","Cell RNA - A549 [nTPM]":"0.9","Cell RNA - AF22 [nTPM]":"1.6","Cell RNA - AN3-CA [nTPM]":"8.4","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"2.0","Cell RNA - BJ [nTPM]":"0.7","Cell RNA - BJ hTERT+ [nTPM]":"2.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.7","Cell RNA - CACO-2 [nTPM]":"1.2","Cell RNA - CAPAN-2 [nTPM]":"1.7","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"11.9","Cell RNA - HaCaT [nTPM]":"1.1","Cell RNA - HAP1 [nTPM]":"7.9","Cell RNA - HBEC3-KT [nTPM]":"1.5","Cell RNA - HBF TERT88 [nTPM]":"1.1","Cell RNA - HDLM-2 [nTPM]":"0.6","Cell RNA - HEK 293 [nTPM]":"2.7","Cell RNA - HEL [nTPM]":"6.0","Cell RNA - HeLa [nTPM]":"3.3","Cell RNA - Hep G2 [nTPM]":"1.7","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"6.0","Cell RNA - HMC-1 [nTPM]":"4.8","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"1.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.7","Cell RNA - hTERT-HME1 [nTPM]":"2.0","Cell RNA - hTERT-RPE1 [nTPM]":"1.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"11.2","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"7.9","Cell RNA - LHCN-M2 [nTPM]":"2.3","Cell RNA - MCF7 [nTPM]":"4.6","Cell RNA - MOLT-4 [nTPM]":"1.6","Cell RNA - NB-4 [nTPM]":"5.4","Cell RNA - NTERA-2 [nTPM]":"6.7","Cell RNA - OE19 [nTPM]":"0.6","Cell RNA - PC-3 [nTPM]":"3.8","Cell RNA - REH [nTPM]":"1.3","Cell RNA - RH-30 [nTPM]":"24.5","Cell RNA - RPMI-8226 [nTPM]":"1.9","Cell RNA - RPTEC TERT1 [nTPM]":"0.9","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"28.3","Cell RNA - SH-SY5Y [nTPM]":"19.6","Cell RNA - SiHa [nTPM]":"5.3","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"3.2","Cell RNA - SuSa [nTPM]":"0.8","Cell RNA - T-47d [nTPM]":"5.8","Cell RNA - THP-1 [nTPM]":"7.4","Cell RNA - TIME [nTPM]":"0.7","Cell RNA - U-138 MG [nTPM]":"2.3","Cell RNA - U-2 OS [nTPM]":"1.8","Cell RNA - U-2197 [nTPM]":"1.7","Cell RNA - U-251 MG [nTPM]":"2.7","Cell RNA - U-266\/70 [nTPM]":"1.2","Cell RNA - U-266\/84 [nTPM]":"0.8","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"2.5","Cell RNA - U-937 [nTPM]":"3.4","Cell RNA - WM-115 [nTPM]":"1.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.2","Blood RNA - eosinophil [nTPM]":"3.2","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"1.3","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"5.8","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"6.5","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"13.2","Brain RNA - basal ganglia [nTPM]":"16.7","Brain RNA - cerebellum [nTPM]":"3.9","Brain RNA - cerebral cortex [nTPM]":"14.2","Brain RNA - hippocampal formation [nTPM]":"16.1","Brain RNA - hypothalamus [nTPM]":"15.7","Brain RNA - medulla oblongata [nTPM]":"17.0","Brain RNA - midbrain [nTPM]":"10.5","Brain RNA - pons [nTPM]":"16.1","Brain RNA - spinal cord [nTPM]":"10.2","Brain RNA - thalamus [nTPM]":"12.7","Brain RNA - white matter [nTPM]":"20.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.4","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"5.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"56.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"27.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"2120.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"2.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.5","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"39.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"1.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.8","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.8","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"18.1","Single Cell Type RNA - Late spermatids [nTPM]":"4980.3","Single Cell Type RNA - Leydig cells [nTPM]":"14.9","Single Cell Type RNA - Macrophages [nTPM]":"6.0","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"29.0","Single Cell Type RNA - monocytes [nTPM]":"3.4","Single Cell Type RNA - Muller glia cells [nTPM]":"6.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"53.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.5","Single Cell Type RNA - Paneth cells [nTPM]":"20.4","Single Cell Type RNA - Peritubular cells [nTPM]":"12.8","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"28.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"76.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.3","Single Cell Type RNA - Spermatocytes [nTPM]":"136.2","Single Cell Type RNA - Spermatogonia [nTPM]":"26.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.7","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.8","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"TRIM37","Gene synonym":["KIAA0898","MUL","POB1","TEF3"],"Ensembl":"ENSG00000108395","Gene description":"Tripartite motif containing 37","Uniprot":["O94972"],"Chromosome":"17","Position":"58982638-59106921","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Ubl conjugation pathway"],"Molecular function":["Repressor","Transferase"],"Disease involvement":["Dwarfism","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"62.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"129.2","Excitatory neurons":"96.7","Inhibitory neurons":"105.2","Late spermatids":"88.8","Spermatocytes":"133.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"30.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"30.4","T-cells":"8.3"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"MCF7":"242.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021911"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA021911":"AB_10964487"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.99e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.8","Tissue RNA - adrenal gland [nTPM]":"12.3","Tissue RNA - amygdala [nTPM]":"16.2","Tissue RNA - appendix [nTPM]":"9.5","Tissue RNA - basal ganglia [nTPM]":"19.3","Tissue RNA - bone marrow [nTPM]":"6.8","Tissue RNA - breast [nTPM]":"8.2","Tissue RNA - cerebellum [nTPM]":"24.8","Tissue RNA - cerebral cortex [nTPM]":"31.4","Tissue RNA - cervix [nTPM]":"7.9","Tissue RNA - choroid plexus [nTPM]":"5.2","Tissue RNA - colon [nTPM]":"9.0","Tissue RNA - duodenum [nTPM]":"6.7","Tissue RNA - endometrium 1 [nTPM]":"8.8","Tissue RNA - epididymis [nTPM]":"10.7","Tissue RNA - esophagus [nTPM]":"8.4","Tissue RNA - fallopian tube [nTPM]":"9.7","Tissue RNA - gallbladder [nTPM]":"8.9","Tissue RNA - heart muscle [nTPM]":"11.5","Tissue RNA - hippocampal formation [nTPM]":"19.5","Tissue RNA - hypothalamus [nTPM]":"13.8","Tissue RNA - kidney [nTPM]":"7.6","Tissue RNA - liver [nTPM]":"8.2","Tissue RNA - lung [nTPM]":"8.9","Tissue RNA - lymph node [nTPM]":"9.0","Tissue RNA - medulla oblongata [nTPM]":"21.4","Tissue RNA - midbrain [nTPM]":"15.2","Tissue RNA - ovary [nTPM]":"6.1","Tissue RNA - pancreas [nTPM]":"7.7","Tissue RNA - parathyroid gland [nTPM]":"8.6","Tissue RNA - pituitary gland [nTPM]":"10.3","Tissue RNA - placenta [nTPM]":"9.4","Tissue RNA - pons [nTPM]":"23.0","Tissue RNA - prostate [nTPM]":"9.4","Tissue RNA - rectum [nTPM]":"7.0","Tissue RNA - retina [nTPM]":"32.9","Tissue RNA - salivary gland [nTPM]":"5.8","Tissue RNA - seminal vesicle [nTPM]":"9.2","Tissue RNA - skeletal muscle [nTPM]":"11.1","Tissue RNA - skin 1 [nTPM]":"7.4","Tissue RNA - small intestine [nTPM]":"6.2","Tissue RNA - smooth muscle [nTPM]":"10.8","Tissue RNA - spinal cord [nTPM]":"9.4","Tissue RNA - spleen [nTPM]":"8.6","Tissue RNA - stomach 1 [nTPM]":"6.5","Tissue RNA - testis [nTPM]":"62.3","Tissue RNA - thalamus [nTPM]":"18.2","Tissue RNA - thymus [nTPM]":"12.1","Tissue RNA - thyroid gland [nTPM]":"13.3","Tissue RNA - tongue [nTPM]":"12.7","Tissue RNA - tonsil [nTPM]":"8.4","Tissue RNA - urinary bladder [nTPM]":"9.0","Tissue RNA - vagina [nTPM]":"6.5","Tissue RNA - white matter [nTPM]":"18.7","Cell RNA - A-431 [nTPM]":"21.4","Cell RNA - A549 [nTPM]":"33.3","Cell RNA - AF22 [nTPM]":"21.9","Cell RNA - AN3-CA [nTPM]":"27.5","Cell RNA - ASC diff [nTPM]":"20.5","Cell RNA - ASC TERT1 [nTPM]":"19.0","Cell RNA - BEWO [nTPM]":"35.3","Cell RNA - BJ [nTPM]":"24.0","Cell RNA - BJ hTERT+ [nTPM]":"36.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"25.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"41.4","Cell RNA - CACO-2 [nTPM]":"19.6","Cell RNA - CAPAN-2 [nTPM]":"14.4","Cell RNA - Daudi [nTPM]":"21.1","Cell RNA - EFO-21 [nTPM]":"36.1","Cell RNA - fHDF\/TERT166 [nTPM]":"25.3","Cell RNA - GAMG [nTPM]":"43.3","Cell RNA - HaCaT [nTPM]":"19.0","Cell RNA - HAP1 [nTPM]":"31.5","Cell RNA - HBEC3-KT [nTPM]":"17.7","Cell RNA - HBF TERT88 [nTPM]":"40.5","Cell RNA - HDLM-2 [nTPM]":"41.8","Cell RNA - HEK 293 [nTPM]":"30.4","Cell RNA - HEL [nTPM]":"32.6","Cell RNA - HeLa [nTPM]":"28.9","Cell RNA - Hep G2 [nTPM]":"27.1","Cell RNA - HHSteC [nTPM]":"36.1","Cell RNA - HL-60 [nTPM]":"16.8","Cell RNA - HMC-1 [nTPM]":"15.8","Cell RNA - HSkMC [nTPM]":"15.4","Cell RNA - hTCEpi [nTPM]":"16.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.5","Cell RNA - hTERT-HME1 [nTPM]":"40.8","Cell RNA - hTERT-RPE1 [nTPM]":"25.8","Cell RNA - HUVEC TERT2 [nTPM]":"33.0","Cell RNA - JURKAT [nTPM]":"19.1","Cell RNA - K-562 [nTPM]":"25.4","Cell RNA - Karpas-707 [nTPM]":"29.7","Cell RNA - LHCN-M2 [nTPM]":"24.9","Cell RNA - MCF7 [nTPM]":"242.4","Cell RNA - MOLT-4 [nTPM]":"34.0","Cell RNA - NB-4 [nTPM]":"9.5","Cell RNA - NTERA-2 [nTPM]":"31.5","Cell RNA - OE19 [nTPM]":"28.9","Cell RNA - PC-3 [nTPM]":"22.0","Cell RNA - REH [nTPM]":"15.0","Cell RNA - RH-30 [nTPM]":"57.1","Cell RNA - RPMI-8226 [nTPM]":"13.7","Cell RNA - RPTEC TERT1 [nTPM]":"24.0","Cell RNA - RT4 [nTPM]":"29.7","Cell RNA - SCLC-21H [nTPM]":"51.7","Cell RNA - SH-SY5Y [nTPM]":"29.9","Cell RNA - SiHa [nTPM]":"24.8","Cell RNA - SK-BR-3 [nTPM]":"10.2","Cell RNA - SK-MEL-30 [nTPM]":"23.2","Cell RNA - SuSa [nTPM]":"26.4","Cell RNA - T-47d [nTPM]":"30.4","Cell RNA - THP-1 [nTPM]":"7.8","Cell RNA - TIME [nTPM]":"25.9","Cell RNA - U-138 MG [nTPM]":"39.5","Cell RNA - U-2 OS [nTPM]":"47.6","Cell RNA - U-2197 [nTPM]":"36.5","Cell RNA - U-251 MG [nTPM]":"27.6","Cell RNA - U-266\/70 [nTPM]":"30.5","Cell RNA - U-266\/84 [nTPM]":"48.5","Cell RNA - U-698 [nTPM]":"18.5","Cell RNA - U-87 MG [nTPM]":"26.8","Cell RNA - U-937 [nTPM]":"17.5","Cell RNA - WM-115 [nTPM]":"18.7","Blood RNA - basophil [nTPM]":"30.4","Blood RNA - classical monocyte [nTPM]":"3.7","Blood RNA - eosinophil [nTPM]":"4.5","Blood RNA - gdT-cell [nTPM]":"7.2","Blood RNA - intermediate monocyte [nTPM]":"2.7","Blood RNA - MAIT T-cell [nTPM]":"6.7","Blood RNA - memory B-cell [nTPM]":"3.6","Blood RNA - memory CD4 T-cell [nTPM]":"4.7","Blood RNA - memory CD8 T-cell [nTPM]":"4.6","Blood RNA - myeloid DC [nTPM]":"4.0","Blood RNA - naive B-cell [nTPM]":"3.9","Blood RNA - naive CD4 T-cell [nTPM]":"4.0","Blood RNA - naive CD8 T-cell [nTPM]":"5.4","Blood RNA - neutrophil [nTPM]":"5.3","Blood RNA - NK-cell [nTPM]":"3.4","Blood RNA - non-classical monocyte [nTPM]":"2.8","Blood RNA - plasmacytoid DC [nTPM]":"3.0","Blood RNA - T-reg [nTPM]":"8.3","Blood RNA - total PBMC [nTPM]":"3.1","Brain RNA - amygdala [nTPM]":"16.2","Brain RNA - basal ganglia [nTPM]":"19.3","Brain RNA - cerebellum [nTPM]":"24.8","Brain RNA - cerebral cortex [nTPM]":"31.4","Brain RNA - hippocampal formation [nTPM]":"19.5","Brain RNA - hypothalamus [nTPM]":"13.8","Brain RNA - medulla oblongata [nTPM]":"21.4","Brain RNA - midbrain [nTPM]":"15.2","Brain RNA - pons [nTPM]":"23.0","Brain RNA - spinal cord [nTPM]":"9.4","Brain RNA - thalamus [nTPM]":"18.2","Brain RNA - white matter [nTPM]":"18.7","Single Cell Type RNA - Adipocytes [nTPM]":"10.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.0","Single Cell Type RNA - Astrocytes [nTPM]":"44.4","Single Cell Type RNA - B-cells [nTPM]":"13.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Bipolar cells [nTPM]":"19.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"24.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"15.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.1","Single Cell Type RNA - dendritic cells [nTPM]":"7.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"10.3","Single Cell Type RNA - Early spermatids [nTPM]":"129.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"30.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.8","Single Cell Type RNA - Endothelial cells [nTPM]":"13.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.0","Single Cell Type RNA - Erythroid cells [nTPM]":"12.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"96.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.6","Single Cell Type RNA - Fibroblasts [nTPM]":"14.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.5","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"18.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.1","Single Cell Type RNA - Hepatocytes [nTPM]":"18.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.7","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"105.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.2","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"9.1","Single Cell Type RNA - Langerhans cells [nTPM]":"6.9","Single Cell Type RNA - Late spermatids [nTPM]":"88.8","Single Cell Type RNA - Leydig cells [nTPM]":"9.9","Single Cell Type RNA - Macrophages [nTPM]":"9.3","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"7.2","Single Cell Type RNA - Muller glia cells [nTPM]":"19.9","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"36.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"43.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.2","Single Cell Type RNA - Paneth cells [nTPM]":"11.3","Single Cell Type RNA - Peritubular cells [nTPM]":"17.7","Single Cell Type RNA - Plasma cells [nTPM]":"15.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"38.8","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.3","Single Cell Type RNA - Spermatocytes [nTPM]":"133.1","Single Cell Type RNA - Spermatogonia [nTPM]":"45.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.8","Single Cell Type RNA - T-cells [nTPM]":"14.7","Single Cell Type RNA - Theca cells [nTPM]":"19.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.1","Single Cell Type RNA - Urothelial cells [nTPM]":"6.8"},{"Gene":"TRIM71","Gene synonym":["LIN-41","LIN41"],"Ensembl":"ENSG00000206557","Gene description":"Tripartite motif containing 71","Uniprot":["Q2Q1W2"],"Chromosome":"3","Position":"32817997-32897824","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["RNA-mediated gene silencing","Ubl conjugation pathway"],"Molecular function":["Developmental protein","RNA-binding","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"testis":"4.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"9.6","Extravillous trophoblasts":"15.6","Inhibitory neurons":"4.5","Oligodendrocyte precursor cells":"4.5","Spermatogonia":"13.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"28","RNA cancer specific FPKM":{"testis cancer":"28.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"31.4","BEWO":"94.5","Hep G2":"63.8","NTERA-2":"84.3","SuSa":"76.3"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038141","HPA038142"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Actin filaments","Focal adhesion sites"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":["Plasma membrane","Actin filaments","Focal adhesion sites"],"Subcellular additional location":null,"Antibody RRID":{"HPA038141":"AB_2675857","HPA038142":"AB_10697240"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"1.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"1.0","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.8","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.9","Tissue RNA - hypothalamus [nTPM]":"0.8","Tissue RNA - kidney [nTPM]":"0.9","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.7","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"4.8","Tissue RNA - thalamus [nTPM]":"0.8","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"31.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"94.5","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"23.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"8.4","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"1.6","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"63.8","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"1.8","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"1.3","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.6","Cell RNA - NB-4 [nTPM]":"6.9","Cell RNA - NTERA-2 [nTPM]":"84.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.6","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"76.3","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.6","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"3.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.0","Brain RNA - basal ganglia [nTPM]":"1.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.8","Brain RNA - hippocampal formation [nTPM]":"0.9","Brain RNA - hypothalamus [nTPM]":"0.8","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.8","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"3.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.9","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.6","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"13.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"TRIO","Gene synonym":["ARHGEF23"],"Ensembl":"ENSG00000038382","Gene description":"Trio Rho guanine nucleotide exchange factor","Uniprot":["O75962"],"Chromosome":"5","Position":"14143342-14532128","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Guanine-nucleotide releasing factor","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"205.7","Excitatory neurons":"400.9","Inhibitory neurons":"443.4","Microglial cells":"308.2","Oligodendrocyte precursor cells":"476.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-87 MG":"215.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008157","HPA064664"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA008157":"AB_1858327","HPA064664":"AB_2685315"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.90e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.11e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Tissue RNA - adipose tissue [nTPM]":"35.3","Tissue RNA - adrenal gland [nTPM]":"20.5","Tissue RNA - amygdala [nTPM]":"31.7","Tissue RNA - appendix [nTPM]":"11.6","Tissue RNA - basal ganglia [nTPM]":"33.3","Tissue RNA - bone marrow [nTPM]":"5.5","Tissue RNA - breast [nTPM]":"31.8","Tissue RNA - cerebellum [nTPM]":"32.2","Tissue RNA - cerebral cortex [nTPM]":"38.6","Tissue RNA - cervix [nTPM]":"23.4","Tissue RNA - choroid plexus [nTPM]":"34.5","Tissue RNA - colon [nTPM]":"36.6","Tissue RNA - duodenum [nTPM]":"6.8","Tissue RNA - endometrium 1 [nTPM]":"38.9","Tissue RNA - epididymis [nTPM]":"15.5","Tissue RNA - esophagus [nTPM]":"14.5","Tissue RNA - fallopian tube [nTPM]":"21.2","Tissue RNA - gallbladder [nTPM]":"18.8","Tissue RNA - heart muscle [nTPM]":"31.9","Tissue RNA - hippocampal formation [nTPM]":"37.2","Tissue RNA - hypothalamus [nTPM]":"33.6","Tissue RNA - kidney [nTPM]":"24.9","Tissue RNA - liver [nTPM]":"22.1","Tissue RNA - lung [nTPM]":"25.7","Tissue RNA - lymph node [nTPM]":"10.2","Tissue RNA - medulla oblongata [nTPM]":"28.1","Tissue RNA - midbrain [nTPM]":"28.1","Tissue RNA - ovary [nTPM]":"52.8","Tissue RNA - pancreas [nTPM]":"20.6","Tissue RNA - parathyroid gland [nTPM]":"9.1","Tissue RNA - pituitary gland [nTPM]":"28.9","Tissue RNA - placenta [nTPM]":"11.6","Tissue RNA - pons [nTPM]":"26.6","Tissue RNA - prostate [nTPM]":"28.2","Tissue RNA - rectum [nTPM]":"13.6","Tissue RNA - retina [nTPM]":"10.2","Tissue RNA - salivary gland [nTPM]":"17.4","Tissue RNA - seminal vesicle [nTPM]":"11.1","Tissue RNA - skeletal muscle [nTPM]":"20.9","Tissue RNA - skin 1 [nTPM]":"18.7","Tissue RNA - small intestine [nTPM]":"27.8","Tissue RNA - smooth muscle [nTPM]":"19.2","Tissue RNA - spinal cord [nTPM]":"26.4","Tissue RNA - spleen [nTPM]":"38.9","Tissue RNA - stomach 1 [nTPM]":"22.9","Tissue RNA - testis [nTPM]":"17.2","Tissue RNA - thalamus [nTPM]":"31.4","Tissue RNA - thymus [nTPM]":"13.3","Tissue RNA - thyroid gland [nTPM]":"17.0","Tissue RNA - tongue [nTPM]":"17.4","Tissue RNA - tonsil [nTPM]":"10.6","Tissue RNA - urinary bladder [nTPM]":"27.1","Tissue RNA - vagina [nTPM]":"20.5","Tissue RNA - white matter [nTPM]":"27.2","Cell RNA - A-431 [nTPM]":"43.7","Cell RNA - A549 [nTPM]":"15.9","Cell RNA - AF22 [nTPM]":"37.2","Cell RNA - AN3-CA [nTPM]":"18.0","Cell RNA - ASC diff [nTPM]":"78.6","Cell RNA - ASC TERT1 [nTPM]":"101.0","Cell RNA - BEWO [nTPM]":"41.3","Cell RNA - BJ [nTPM]":"40.4","Cell RNA - BJ hTERT+ [nTPM]":"49.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"32.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"36.9","Cell RNA - CACO-2 [nTPM]":"10.3","Cell RNA - CAPAN-2 [nTPM]":"17.4","Cell RNA - Daudi [nTPM]":"10.4","Cell RNA - EFO-21 [nTPM]":"28.0","Cell RNA - fHDF\/TERT166 [nTPM]":"56.6","Cell RNA - GAMG [nTPM]":"79.6","Cell RNA - HaCaT [nTPM]":"13.0","Cell RNA - HAP1 [nTPM]":"6.5","Cell RNA - HBEC3-KT [nTPM]":"19.4","Cell RNA - HBF TERT88 [nTPM]":"66.6","Cell RNA - HDLM-2 [nTPM]":"25.8","Cell RNA - HEK 293 [nTPM]":"8.0","Cell RNA - HEL [nTPM]":"5.5","Cell RNA - HeLa [nTPM]":"46.1","Cell RNA - Hep G2 [nTPM]":"13.2","Cell RNA - HHSteC [nTPM]":"40.0","Cell RNA - HL-60 [nTPM]":"13.9","Cell RNA - HMC-1 [nTPM]":"14.8","Cell RNA - HSkMC [nTPM]":"47.6","Cell RNA - hTCEpi [nTPM]":"19.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"114.4","Cell RNA - hTERT-HME1 [nTPM]":"36.4","Cell RNA - hTERT-RPE1 [nTPM]":"30.3","Cell RNA - HUVEC TERT2 [nTPM]":"28.8","Cell RNA - JURKAT [nTPM]":"6.8","Cell RNA - K-562 [nTPM]":"1.4","Cell RNA - Karpas-707 [nTPM]":"6.8","Cell RNA - LHCN-M2 [nTPM]":"78.7","Cell RNA - MCF7 [nTPM]":"8.3","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"9.5","Cell RNA - NTERA-2 [nTPM]":"9.3","Cell RNA - OE19 [nTPM]":"4.8","Cell RNA - PC-3 [nTPM]":"13.7","Cell RNA - REH [nTPM]":"9.9","Cell RNA - RH-30 [nTPM]":"22.9","Cell RNA - RPMI-8226 [nTPM]":"34.2","Cell RNA - RPTEC TERT1 [nTPM]":"31.6","Cell RNA - RT4 [nTPM]":"20.5","Cell RNA - SCLC-21H [nTPM]":"17.1","Cell RNA - SH-SY5Y [nTPM]":"67.5","Cell RNA - SiHa [nTPM]":"34.3","Cell RNA - SK-BR-3 [nTPM]":"9.0","Cell RNA - SK-MEL-30 [nTPM]":"18.9","Cell RNA - SuSa [nTPM]":"47.1","Cell RNA - T-47d [nTPM]":"5.3","Cell RNA - THP-1 [nTPM]":"2.0","Cell RNA - TIME [nTPM]":"66.4","Cell RNA - U-138 MG [nTPM]":"61.4","Cell RNA - U-2 OS [nTPM]":"38.3","Cell RNA - U-2197 [nTPM]":"44.7","Cell RNA - U-251 MG [nTPM]":"48.4","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"2.2","Cell RNA - U-698 [nTPM]":"12.9","Cell RNA - U-87 MG [nTPM]":"215.1","Cell RNA - U-937 [nTPM]":"8.8","Cell RNA - WM-115 [nTPM]":"14.8","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.6","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"31.7","Brain RNA - basal ganglia [nTPM]":"33.3","Brain RNA - cerebellum [nTPM]":"32.2","Brain RNA - cerebral cortex [nTPM]":"38.6","Brain RNA - hippocampal formation [nTPM]":"37.2","Brain RNA - hypothalamus [nTPM]":"33.6","Brain RNA - medulla oblongata [nTPM]":"28.1","Brain RNA - midbrain [nTPM]":"28.1","Brain RNA - pons [nTPM]":"26.6","Brain RNA - spinal cord [nTPM]":"26.4","Brain RNA - thalamus [nTPM]":"31.4","Brain RNA - white matter [nTPM]":"27.2","Single Cell Type RNA - Adipocytes [nTPM]":"33.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.9","Single Cell Type RNA - Astrocytes [nTPM]":"205.7","Single Cell Type RNA - B-cells [nTPM]":"16.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Bipolar cells [nTPM]":"30.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"21.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.7","Single Cell Type RNA - dendritic cells [nTPM]":"5.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"21.2","Single Cell Type RNA - Early spermatids [nTPM]":"2.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"24.8","Single Cell Type RNA - Endothelial cells [nTPM]":"28.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.0","Single Cell Type RNA - Erythroid cells [nTPM]":"6.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"400.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"22.0","Single Cell Type RNA - Fibroblasts [nTPM]":"38.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"34.2","Single Cell Type RNA - granulocytes [nTPM]":"17.7","Single Cell Type RNA - Granulosa cells [nTPM]":"17.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"17.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.2","Single Cell Type RNA - Horizontal cells [nTPM]":"28.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"443.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.6","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"15.4","Single Cell Type RNA - Langerhans cells [nTPM]":"22.1","Single Cell Type RNA - Late spermatids [nTPM]":"6.6","Single Cell Type RNA - Leydig cells [nTPM]":"78.6","Single Cell Type RNA - Macrophages [nTPM]":"20.2","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"308.2","Single Cell Type RNA - monocytes [nTPM]":"12.1","Single Cell Type RNA - Muller glia cells [nTPM]":"7.3","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"476.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"80.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"38.5","Single Cell Type RNA - Paneth cells [nTPM]":"14.9","Single Cell Type RNA - Peritubular cells [nTPM]":"42.9","Single Cell Type RNA - Plasma cells [nTPM]":"29.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"52.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.0","Single Cell Type RNA - Spermatocytes [nTPM]":"3.5","Single Cell Type RNA - Spermatogonia [nTPM]":"6.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.2","Single Cell Type RNA - T-cells [nTPM]":"3.8","Single Cell Type RNA - Theca cells [nTPM]":"11.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.4","Single Cell Type RNA - Urothelial cells [nTPM]":"20.3"},{"Gene":"TRIP12","Gene synonym":["KIAA0045","TRIPC","ULF"],"Ensembl":"ENSG00000153827","Gene description":"Thyroid hormone receptor interactor 12","Uniprot":["Q14669"],"Chromosome":"2","Position":"229763837-229923239","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Autism spectrum disorder","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"251.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036835","HPA045893"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA036835":"AB_2675340","HPA045893":"AB_2679486"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.60e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Tissue RNA - adipose tissue [nTPM]":"48.2","Tissue RNA - adrenal gland [nTPM]":"32.3","Tissue RNA - amygdala [nTPM]":"20.2","Tissue RNA - appendix [nTPM]":"47.1","Tissue RNA - basal ganglia [nTPM]":"26.7","Tissue RNA - bone marrow [nTPM]":"53.9","Tissue RNA - breast [nTPM]":"33.6","Tissue RNA - cerebellum [nTPM]":"20.2","Tissue RNA - cerebral cortex [nTPM]":"31.4","Tissue RNA - cervix [nTPM]":"34.8","Tissue RNA - choroid plexus [nTPM]":"15.7","Tissue RNA - colon [nTPM]":"40.8","Tissue RNA - duodenum [nTPM]":"25.6","Tissue RNA - endometrium 1 [nTPM]":"30.8","Tissue RNA - epididymis [nTPM]":"33.4","Tissue RNA - esophagus [nTPM]":"47.6","Tissue RNA - fallopian tube [nTPM]":"28.1","Tissue RNA - gallbladder [nTPM]":"33.9","Tissue RNA - heart muscle [nTPM]":"41.5","Tissue RNA - hippocampal formation [nTPM]":"16.0","Tissue RNA - hypothalamus [nTPM]":"25.4","Tissue RNA - kidney [nTPM]":"41.3","Tissue RNA - liver [nTPM]":"42.8","Tissue RNA - lung [nTPM]":"33.3","Tissue RNA - lymph node [nTPM]":"48.2","Tissue RNA - medulla oblongata [nTPM]":"20.7","Tissue RNA - midbrain [nTPM]":"20.8","Tissue RNA - ovary [nTPM]":"32.7","Tissue RNA - pancreas [nTPM]":"29.3","Tissue RNA - parathyroid gland [nTPM]":"45.0","Tissue RNA - pituitary gland [nTPM]":"24.8","Tissue RNA - placenta [nTPM]":"44.6","Tissue RNA - pons [nTPM]":"22.1","Tissue RNA - prostate [nTPM]":"39.9","Tissue RNA - rectum [nTPM]":"33.9","Tissue RNA - retina [nTPM]":"34.8","Tissue RNA - salivary gland [nTPM]":"30.2","Tissue RNA - seminal vesicle [nTPM]":"33.0","Tissue RNA - skeletal muscle [nTPM]":"81.7","Tissue RNA - skin 1 [nTPM]":"29.3","Tissue RNA - small intestine [nTPM]":"27.6","Tissue RNA - smooth muscle [nTPM]":"38.2","Tissue RNA - spinal cord [nTPM]":"17.9","Tissue RNA - spleen [nTPM]":"41.1","Tissue RNA - stomach 1 [nTPM]":"39.1","Tissue RNA - testis [nTPM]":"127.7","Tissue RNA - thalamus [nTPM]":"21.5","Tissue RNA - thymus [nTPM]":"60.3","Tissue RNA - thyroid gland [nTPM]":"44.5","Tissue RNA - tongue [nTPM]":"59.0","Tissue RNA - tonsil [nTPM]":"56.3","Tissue RNA - urinary bladder [nTPM]":"46.3","Tissue RNA - vagina [nTPM]":"26.5","Tissue RNA - white matter [nTPM]":"30.0","Cell RNA - A-431 [nTPM]":"97.1","Cell RNA - A549 [nTPM]":"100.7","Cell RNA - AF22 [nTPM]":"96.2","Cell RNA - AN3-CA [nTPM]":"79.0","Cell RNA - ASC diff [nTPM]":"94.9","Cell RNA - ASC TERT1 [nTPM]":"106.2","Cell RNA - BEWO [nTPM]":"88.3","Cell RNA - BJ [nTPM]":"144.5","Cell RNA - BJ hTERT+ [nTPM]":"103.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"106.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"118.7","Cell RNA - CACO-2 [nTPM]":"80.5","Cell RNA - CAPAN-2 [nTPM]":"75.3","Cell RNA - Daudi [nTPM]":"37.8","Cell RNA - EFO-21 [nTPM]":"96.2","Cell RNA - fHDF\/TERT166 [nTPM]":"135.6","Cell RNA - GAMG [nTPM]":"129.5","Cell RNA - HaCaT [nTPM]":"76.3","Cell RNA - HAP1 [nTPM]":"140.5","Cell RNA - HBEC3-KT [nTPM]":"105.9","Cell RNA - HBF TERT88 [nTPM]":"159.3","Cell RNA - HDLM-2 [nTPM]":"132.4","Cell RNA - HEK 293 [nTPM]":"52.9","Cell RNA - HEL [nTPM]":"264.1","Cell RNA - HeLa [nTPM]":"84.4","Cell RNA - Hep G2 [nTPM]":"78.3","Cell RNA - HHSteC [nTPM]":"76.4","Cell RNA - HL-60 [nTPM]":"195.8","Cell RNA - HMC-1 [nTPM]":"163.2","Cell RNA - HSkMC [nTPM]":"88.1","Cell RNA - hTCEpi [nTPM]":"80.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"174.9","Cell RNA - hTERT-HME1 [nTPM]":"108.5","Cell RNA - hTERT-RPE1 [nTPM]":"74.9","Cell RNA - HUVEC TERT2 [nTPM]":"145.1","Cell RNA - JURKAT [nTPM]":"88.2","Cell RNA - K-562 [nTPM]":"188.2","Cell RNA - Karpas-707 [nTPM]":"38.2","Cell RNA - LHCN-M2 [nTPM]":"122.5","Cell RNA - MCF7 [nTPM]":"72.5","Cell RNA - MOLT-4 [nTPM]":"105.3","Cell RNA - NB-4 [nTPM]":"68.5","Cell RNA - NTERA-2 [nTPM]":"77.0","Cell RNA - OE19 [nTPM]":"50.3","Cell RNA - PC-3 [nTPM]":"47.7","Cell RNA - REH [nTPM]":"94.8","Cell RNA - RH-30 [nTPM]":"189.8","Cell RNA - RPMI-8226 [nTPM]":"33.6","Cell RNA - RPTEC TERT1 [nTPM]":"75.7","Cell RNA - RT4 [nTPM]":"156.4","Cell RNA - SCLC-21H [nTPM]":"94.4","Cell RNA - SH-SY5Y [nTPM]":"67.5","Cell RNA - SiHa [nTPM]":"1.6","Cell RNA - SK-BR-3 [nTPM]":"51.9","Cell RNA - SK-MEL-30 [nTPM]":"97.7","Cell RNA - SuSa [nTPM]":"85.1","Cell RNA - T-47d [nTPM]":"48.2","Cell RNA - THP-1 [nTPM]":"118.3","Cell RNA - TIME [nTPM]":"188.8","Cell RNA - U-138 MG [nTPM]":"133.9","Cell RNA - U-2 OS [nTPM]":"94.7","Cell RNA - U-2197 [nTPM]":"84.9","Cell RNA - U-251 MG [nTPM]":"115.5","Cell RNA - U-266\/70 [nTPM]":"66.4","Cell RNA - U-266\/84 [nTPM]":"79.3","Cell RNA - U-698 [nTPM]":"119.0","Cell RNA - U-87 MG [nTPM]":"103.8","Cell RNA - U-937 [nTPM]":"77.0","Cell RNA - WM-115 [nTPM]":"116.6","Blood RNA - basophil [nTPM]":"34.0","Blood RNA - classical monocyte [nTPM]":"14.2","Blood RNA - eosinophil [nTPM]":"23.6","Blood RNA - gdT-cell [nTPM]":"12.9","Blood RNA - intermediate monocyte [nTPM]":"16.2","Blood RNA - MAIT T-cell [nTPM]":"13.1","Blood RNA - memory B-cell [nTPM]":"9.6","Blood RNA - memory CD4 T-cell [nTPM]":"12.0","Blood RNA - memory CD8 T-cell [nTPM]":"12.7","Blood RNA - myeloid DC [nTPM]":"13.4","Blood RNA - naive B-cell [nTPM]":"8.9","Blood RNA - naive CD4 T-cell [nTPM]":"9.5","Blood RNA - naive CD8 T-cell [nTPM]":"9.7","Blood RNA - neutrophil [nTPM]":"36.0","Blood RNA - NK-cell [nTPM]":"13.9","Blood RNA - non-classical monocyte [nTPM]":"18.7","Blood RNA - plasmacytoid DC [nTPM]":"12.6","Blood RNA - T-reg [nTPM]":"19.5","Blood RNA - total PBMC [nTPM]":"9.8","Brain RNA - amygdala [nTPM]":"20.2","Brain RNA - basal ganglia [nTPM]":"26.7","Brain RNA - cerebellum [nTPM]":"20.2","Brain RNA - cerebral cortex [nTPM]":"31.4","Brain RNA - hippocampal formation [nTPM]":"16.0","Brain RNA - hypothalamus [nTPM]":"25.4","Brain RNA - medulla oblongata [nTPM]":"20.7","Brain RNA - midbrain [nTPM]":"20.8","Brain RNA - pons [nTPM]":"22.1","Brain RNA - spinal cord [nTPM]":"17.9","Brain RNA - thalamus [nTPM]":"21.5","Brain RNA - white matter [nTPM]":"30.0","Single Cell Type RNA - Adipocytes [nTPM]":"78.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"89.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"51.2","Single Cell Type RNA - Astrocytes [nTPM]":"85.8","Single Cell Type RNA - B-cells [nTPM]":"43.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"31.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"36.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.6","Single Cell Type RNA - Bipolar cells [nTPM]":"31.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"41.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"29.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"91.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"34.3","Single Cell Type RNA - Club cells [nTPM]":"52.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.0","Single Cell Type RNA - dendritic cells [nTPM]":"60.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"57.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"37.5","Single Cell Type RNA - Early spermatids [nTPM]":"119.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"63.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"65.2","Single Cell Type RNA - Endothelial cells [nTPM]":"59.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.6","Single Cell Type RNA - Erythroid cells [nTPM]":"40.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"147.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"45.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"25.1","Single Cell Type RNA - Fibroblasts [nTPM]":"43.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"56.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"73.5","Single Cell Type RNA - granulocytes [nTPM]":"39.2","Single Cell Type RNA - Granulosa cells [nTPM]":"53.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"50.0","Single Cell Type RNA - Hepatocytes [nTPM]":"54.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"35.1","Single Cell Type RNA - Horizontal cells [nTPM]":"42.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"130.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"32.5","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"89.6","Single Cell Type RNA - Langerhans cells [nTPM]":"32.2","Single Cell Type RNA - Late spermatids [nTPM]":"102.1","Single Cell Type RNA - Leydig cells [nTPM]":"34.8","Single Cell Type RNA - Macrophages [nTPM]":"70.8","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"122.7","Single Cell Type RNA - monocytes [nTPM]":"63.9","Single Cell Type RNA - Muller glia cells [nTPM]":"25.8","Single Cell Type RNA - NK-cells [nTPM]":"56.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"127.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"251.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"57.8","Single Cell Type RNA - Paneth cells [nTPM]":"35.0","Single Cell Type RNA - Peritubular cells [nTPM]":"45.5","Single Cell Type RNA - Plasma cells [nTPM]":"52.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"44.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"25.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"34.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"73.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"32.1","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"57.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"45.0","Single Cell Type RNA - Spermatocytes [nTPM]":"137.2","Single Cell Type RNA - Spermatogonia [nTPM]":"59.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"43.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"36.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"42.4","Single Cell Type RNA - T-cells [nTPM]":"47.0","Single Cell Type RNA - Theca cells [nTPM]":"60.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"31.9","Single Cell Type RNA - Urothelial cells [nTPM]":"54.5"},{"Gene":"TRIT1","Gene synonym":["FLJ20061","IPT"],"Ensembl":"ENSG00000043514","Gene description":"TRNA isopentenyltransferase 1","Uniprot":["Q9H3H1"],"Chromosome":"1","Position":"39838110-39883511","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["tRNA processing"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024174","HPA027330"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA024174":"AB_1858346","HPA027330":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.80e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.34e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.08e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.0","Tissue RNA - adrenal gland [nTPM]":"9.9","Tissue RNA - amygdala [nTPM]":"13.1","Tissue RNA - appendix [nTPM]":"7.0","Tissue RNA - basal ganglia [nTPM]":"13.1","Tissue RNA - bone marrow [nTPM]":"5.6","Tissue RNA - breast [nTPM]":"12.9","Tissue RNA - cerebellum [nTPM]":"14.7","Tissue RNA - cerebral cortex [nTPM]":"16.1","Tissue RNA - cervix [nTPM]":"15.6","Tissue RNA - choroid plexus [nTPM]":"12.8","Tissue RNA - colon [nTPM]":"13.6","Tissue RNA - duodenum [nTPM]":"6.3","Tissue RNA - endometrium 1 [nTPM]":"14.7","Tissue RNA - epididymis [nTPM]":"15.3","Tissue RNA - esophagus [nTPM]":"18.5","Tissue RNA - fallopian tube [nTPM]":"13.1","Tissue RNA - gallbladder [nTPM]":"6.0","Tissue RNA - heart muscle [nTPM]":"15.2","Tissue RNA - hippocampal formation [nTPM]":"13.1","Tissue RNA - hypothalamus [nTPM]":"14.0","Tissue RNA - kidney [nTPM]":"15.3","Tissue RNA - liver [nTPM]":"13.0","Tissue RNA - lung [nTPM]":"9.2","Tissue RNA - lymph node [nTPM]":"8.4","Tissue RNA - medulla oblongata [nTPM]":"12.1","Tissue RNA - midbrain [nTPM]":"12.1","Tissue RNA - ovary [nTPM]":"14.3","Tissue RNA - pancreas [nTPM]":"21.5","Tissue RNA - parathyroid gland [nTPM]":"9.7","Tissue RNA - pituitary gland [nTPM]":"16.7","Tissue RNA - placenta [nTPM]":"11.8","Tissue RNA - pons [nTPM]":"12.6","Tissue RNA - prostate [nTPM]":"19.9","Tissue RNA - rectum [nTPM]":"10.5","Tissue RNA - retina [nTPM]":"14.7","Tissue RNA - salivary gland [nTPM]":"13.6","Tissue RNA - seminal vesicle [nTPM]":"10.9","Tissue RNA - skeletal muscle [nTPM]":"9.5","Tissue RNA - skin 1 [nTPM]":"21.6","Tissue RNA - small intestine [nTPM]":"11.1","Tissue RNA - smooth muscle [nTPM]":"10.0","Tissue RNA - spinal cord [nTPM]":"12.0","Tissue RNA - spleen [nTPM]":"12.6","Tissue RNA - stomach 1 [nTPM]":"12.0","Tissue RNA - testis [nTPM]":"11.9","Tissue RNA - thalamus [nTPM]":"13.9","Tissue RNA - thymus [nTPM]":"11.8","Tissue RNA - thyroid gland [nTPM]":"16.8","Tissue RNA - tongue [nTPM]":"4.4","Tissue RNA - tonsil [nTPM]":"9.9","Tissue RNA - urinary bladder [nTPM]":"15.3","Tissue RNA - vagina [nTPM]":"16.8","Tissue RNA - white matter [nTPM]":"14.3","Cell RNA - A-431 [nTPM]":"20.5","Cell RNA - A549 [nTPM]":"9.4","Cell RNA - AF22 [nTPM]":"23.0","Cell RNA - AN3-CA [nTPM]":"18.4","Cell RNA - ASC diff [nTPM]":"10.6","Cell RNA - ASC TERT1 [nTPM]":"16.5","Cell RNA - BEWO [nTPM]":"29.8","Cell RNA - BJ [nTPM]":"11.1","Cell RNA - BJ hTERT+ [nTPM]":"17.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"22.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.8","Cell RNA - CACO-2 [nTPM]":"20.0","Cell RNA - CAPAN-2 [nTPM]":"20.6","Cell RNA - Daudi [nTPM]":"11.5","Cell RNA - EFO-21 [nTPM]":"17.4","Cell RNA - fHDF\/TERT166 [nTPM]":"11.3","Cell RNA - GAMG [nTPM]":"12.2","Cell RNA - HaCaT [nTPM]":"18.9","Cell RNA - HAP1 [nTPM]":"29.4","Cell RNA - HBEC3-KT [nTPM]":"22.7","Cell RNA - HBF TERT88 [nTPM]":"29.7","Cell RNA - HDLM-2 [nTPM]":"17.0","Cell RNA - HEK 293 [nTPM]":"15.6","Cell RNA - HEL [nTPM]":"25.6","Cell RNA - HeLa [nTPM]":"22.8","Cell RNA - Hep G2 [nTPM]":"13.5","Cell RNA - HHSteC [nTPM]":"21.8","Cell RNA - HL-60 [nTPM]":"21.0","Cell RNA - HMC-1 [nTPM]":"14.4","Cell RNA - HSkMC [nTPM]":"13.3","Cell RNA - hTCEpi [nTPM]":"21.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.0","Cell RNA - hTERT-HME1 [nTPM]":"26.9","Cell RNA - hTERT-RPE1 [nTPM]":"25.9","Cell RNA - HUVEC TERT2 [nTPM]":"18.0","Cell RNA - JURKAT [nTPM]":"27.1","Cell RNA - K-562 [nTPM]":"31.7","Cell RNA - Karpas-707 [nTPM]":"14.1","Cell RNA - LHCN-M2 [nTPM]":"13.8","Cell RNA - MCF7 [nTPM]":"11.5","Cell RNA - MOLT-4 [nTPM]":"14.3","Cell RNA - NB-4 [nTPM]":"30.7","Cell RNA - NTERA-2 [nTPM]":"31.6","Cell RNA - OE19 [nTPM]":"17.4","Cell RNA - PC-3 [nTPM]":"6.2","Cell RNA - REH [nTPM]":"21.1","Cell RNA - RH-30 [nTPM]":"21.6","Cell RNA - RPMI-8226 [nTPM]":"23.3","Cell RNA - RPTEC TERT1 [nTPM]":"21.1","Cell RNA - RT4 [nTPM]":"27.3","Cell RNA - SCLC-21H [nTPM]":"21.9","Cell RNA - SH-SY5Y [nTPM]":"16.6","Cell RNA - SiHa [nTPM]":"15.2","Cell RNA - SK-BR-3 [nTPM]":"10.3","Cell RNA - SK-MEL-30 [nTPM]":"17.7","Cell RNA - SuSa [nTPM]":"23.0","Cell RNA - T-47d [nTPM]":"12.5","Cell RNA - THP-1 [nTPM]":"37.5","Cell RNA - TIME [nTPM]":"11.0","Cell RNA - U-138 MG [nTPM]":"12.8","Cell RNA - U-2 OS [nTPM]":"18.2","Cell RNA - U-2197 [nTPM]":"21.1","Cell RNA - U-251 MG [nTPM]":"21.3","Cell RNA - U-266\/70 [nTPM]":"19.4","Cell RNA - U-266\/84 [nTPM]":"13.2","Cell RNA - U-698 [nTPM]":"22.5","Cell RNA - U-87 MG [nTPM]":"14.2","Cell RNA - U-937 [nTPM]":"24.6","Cell RNA - WM-115 [nTPM]":"12.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"5.4","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"2.0","Blood RNA - intermediate monocyte [nTPM]":"3.9","Blood RNA - MAIT T-cell [nTPM]":"3.7","Blood RNA - memory B-cell [nTPM]":"2.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.8","Blood RNA - memory CD8 T-cell [nTPM]":"2.2","Blood RNA - myeloid DC [nTPM]":"10.4","Blood RNA - naive B-cell [nTPM]":"2.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.9","Blood RNA - naive CD8 T-cell [nTPM]":"2.7","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"2.0","Blood RNA - non-classical monocyte [nTPM]":"5.3","Blood RNA - plasmacytoid DC [nTPM]":"10.1","Blood RNA - T-reg [nTPM]":"2.3","Blood RNA - total PBMC [nTPM]":"2.4","Brain RNA - amygdala [nTPM]":"13.1","Brain RNA - basal ganglia [nTPM]":"13.1","Brain RNA - cerebellum [nTPM]":"14.7","Brain RNA - cerebral cortex [nTPM]":"16.1","Brain RNA - hippocampal formation [nTPM]":"13.1","Brain RNA - hypothalamus [nTPM]":"14.0","Brain RNA - medulla oblongata [nTPM]":"12.1","Brain RNA - midbrain [nTPM]":"12.1","Brain RNA - pons [nTPM]":"12.6","Brain RNA - spinal cord [nTPM]":"12.0","Brain RNA - thalamus [nTPM]":"13.9","Brain RNA - white matter [nTPM]":"14.3","Single Cell Type RNA - Adipocytes [nTPM]":"4.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.8","Single Cell Type RNA - Astrocytes [nTPM]":"16.6","Single Cell Type RNA - B-cells [nTPM]":"8.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"4.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"11.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"34.1","Single Cell Type RNA - dendritic cells [nTPM]":"10.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"12.2","Single Cell Type RNA - Early spermatids [nTPM]":"5.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.8","Single Cell Type RNA - Endothelial cells [nTPM]":"6.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.2","Single Cell Type RNA - Erythroid cells [nTPM]":"13.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"31.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"32.8","Single Cell Type RNA - Fibroblasts [nTPM]":"9.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.1","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"9.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.9","Single Cell Type RNA - Hepatocytes [nTPM]":"7.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.2","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"26.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.8","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.9","Single Cell Type RNA - Langerhans cells [nTPM]":"5.1","Single Cell Type RNA - Late spermatids [nTPM]":"3.1","Single Cell Type RNA - Leydig cells [nTPM]":"9.6","Single Cell Type RNA - Macrophages [nTPM]":"7.3","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"26.2","Single Cell Type RNA - monocytes [nTPM]":"12.3","Single Cell Type RNA - Muller glia cells [nTPM]":"4.9","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"34.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"31.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.5","Single Cell Type RNA - Paneth cells [nTPM]":"5.8","Single Cell Type RNA - Peritubular cells [nTPM]":"11.3","Single Cell Type RNA - Plasma cells [nTPM]":"3.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"25.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.9","Single Cell Type RNA - Spermatocytes [nTPM]":"24.9","Single Cell Type RNA - Spermatogonia [nTPM]":"16.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.6","Single Cell Type RNA - T-cells [nTPM]":"6.1","Single Cell Type RNA - Theca cells [nTPM]":"10.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.0","Single Cell Type RNA - Urothelial cells [nTPM]":"11.2"},{"Gene":"TRMT1","Gene synonym":["FLJ20244","TRM1"],"Ensembl":"ENSG00000104907","Gene description":"TRNA methyltransferase 1","Uniprot":["Q9NXH9"],"Chromosome":"19","Position":"13104902-13117567","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["tRNA processing"],"Molecular function":["Methyltransferase","RNA-binding","Transferase","tRNA-binding"],"Disease involvement":["Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Kupffer cells":"80.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041130","HPA041380"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA041130":"AB_10803995","HPA041380":"AB_10793873"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.87e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Tissue RNA - adipose tissue [nTPM]":"22.0","Tissue RNA - adrenal gland [nTPM]":"19.8","Tissue RNA - amygdala [nTPM]":"16.5","Tissue RNA - appendix [nTPM]":"16.2","Tissue RNA - basal ganglia [nTPM]":"15.3","Tissue RNA - bone marrow [nTPM]":"21.1","Tissue RNA - breast [nTPM]":"21.0","Tissue RNA - cerebellum [nTPM]":"14.7","Tissue RNA - cerebral cortex [nTPM]":"22.1","Tissue RNA - cervix [nTPM]":"24.3","Tissue RNA - choroid plexus [nTPM]":"14.8","Tissue RNA - colon [nTPM]":"20.0","Tissue RNA - duodenum [nTPM]":"11.8","Tissue RNA - endometrium 1 [nTPM]":"22.9","Tissue RNA - epididymis [nTPM]":"6.3","Tissue RNA - esophagus [nTPM]":"22.3","Tissue RNA - fallopian tube [nTPM]":"23.6","Tissue RNA - gallbladder [nTPM]":"8.9","Tissue RNA - heart muscle [nTPM]":"17.3","Tissue RNA - hippocampal formation [nTPM]":"15.5","Tissue RNA - hypothalamus [nTPM]":"14.7","Tissue RNA - kidney [nTPM]":"18.0","Tissue RNA - liver [nTPM]":"22.1","Tissue RNA - lung [nTPM]":"17.3","Tissue RNA - lymph node [nTPM]":"23.2","Tissue RNA - medulla oblongata [nTPM]":"16.0","Tissue RNA - midbrain [nTPM]":"14.8","Tissue RNA - ovary [nTPM]":"28.7","Tissue RNA - pancreas [nTPM]":"25.4","Tissue RNA - parathyroid gland [nTPM]":"10.0","Tissue RNA - pituitary gland [nTPM]":"17.2","Tissue RNA - placenta [nTPM]":"11.3","Tissue RNA - pons [nTPM]":"16.8","Tissue RNA - prostate [nTPM]":"23.0","Tissue RNA - rectum [nTPM]":"10.9","Tissue RNA - retina [nTPM]":"6.5","Tissue RNA - salivary gland [nTPM]":"17.0","Tissue RNA - seminal vesicle [nTPM]":"11.4","Tissue RNA - skeletal muscle [nTPM]":"28.8","Tissue RNA - skin 1 [nTPM]":"23.4","Tissue RNA - small intestine [nTPM]":"21.7","Tissue RNA - smooth muscle [nTPM]":"12.5","Tissue RNA - spinal cord [nTPM]":"14.2","Tissue RNA - spleen [nTPM]":"30.6","Tissue RNA - stomach 1 [nTPM]":"18.9","Tissue RNA - testis [nTPM]":"16.8","Tissue RNA - thalamus [nTPM]":"16.2","Tissue RNA - thymus [nTPM]":"11.6","Tissue RNA - thyroid gland [nTPM]":"19.2","Tissue RNA - tongue [nTPM]":"10.5","Tissue RNA - tonsil [nTPM]":"15.9","Tissue RNA - urinary bladder [nTPM]":"22.3","Tissue RNA - vagina [nTPM]":"22.2","Tissue RNA - white matter [nTPM]":"17.6","Cell RNA - A-431 [nTPM]":"38.6","Cell RNA - A549 [nTPM]":"25.3","Cell RNA - AF22 [nTPM]":"26.9","Cell RNA - AN3-CA [nTPM]":"46.0","Cell RNA - ASC diff [nTPM]":"26.7","Cell RNA - ASC TERT1 [nTPM]":"34.1","Cell RNA - BEWO [nTPM]":"38.7","Cell RNA - BJ [nTPM]":"42.1","Cell RNA - BJ hTERT+ [nTPM]":"20.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"45.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"39.1","Cell RNA - CACO-2 [nTPM]":"27.4","Cell RNA - CAPAN-2 [nTPM]":"30.8","Cell RNA - Daudi [nTPM]":"47.7","Cell RNA - EFO-21 [nTPM]":"53.6","Cell RNA - fHDF\/TERT166 [nTPM]":"22.9","Cell RNA - GAMG [nTPM]":"23.7","Cell RNA - HaCaT [nTPM]":"34.8","Cell RNA - HAP1 [nTPM]":"45.2","Cell RNA - HBEC3-KT [nTPM]":"37.3","Cell RNA - HBF TERT88 [nTPM]":"20.9","Cell RNA - HDLM-2 [nTPM]":"31.3","Cell RNA - HEK 293 [nTPM]":"62.8","Cell RNA - HEL [nTPM]":"38.0","Cell RNA - HeLa [nTPM]":"68.7","Cell RNA - Hep G2 [nTPM]":"46.5","Cell RNA - HHSteC [nTPM]":"48.7","Cell RNA - HL-60 [nTPM]":"77.2","Cell RNA - HMC-1 [nTPM]":"43.1","Cell RNA - HSkMC [nTPM]":"48.4","Cell RNA - hTCEpi [nTPM]":"48.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"47.3","Cell RNA - hTERT-HME1 [nTPM]":"44.1","Cell RNA - hTERT-RPE1 [nTPM]":"28.9","Cell RNA - HUVEC TERT2 [nTPM]":"33.8","Cell RNA - JURKAT [nTPM]":"35.2","Cell RNA - K-562 [nTPM]":"83.7","Cell RNA - Karpas-707 [nTPM]":"14.9","Cell RNA - LHCN-M2 [nTPM]":"28.6","Cell RNA - MCF7 [nTPM]":"42.6","Cell RNA - MOLT-4 [nTPM]":"31.7","Cell RNA - NB-4 [nTPM]":"83.3","Cell RNA - NTERA-2 [nTPM]":"64.0","Cell RNA - OE19 [nTPM]":"24.2","Cell RNA - PC-3 [nTPM]":"57.5","Cell RNA - REH [nTPM]":"52.5","Cell RNA - RH-30 [nTPM]":"34.6","Cell RNA - RPMI-8226 [nTPM]":"65.8","Cell RNA - RPTEC TERT1 [nTPM]":"28.3","Cell RNA - RT4 [nTPM]":"38.2","Cell RNA - SCLC-21H [nTPM]":"63.5","Cell RNA - SH-SY5Y [nTPM]":"28.9","Cell RNA - SiHa [nTPM]":"26.2","Cell RNA - SK-BR-3 [nTPM]":"53.7","Cell RNA - SK-MEL-30 [nTPM]":"44.8","Cell RNA - SuSa [nTPM]":"19.4","Cell RNA - T-47d [nTPM]":"21.0","Cell RNA - THP-1 [nTPM]":"42.8","Cell RNA - TIME [nTPM]":"38.2","Cell RNA - U-138 MG [nTPM]":"65.1","Cell RNA - U-2 OS [nTPM]":"25.5","Cell RNA - U-2197 [nTPM]":"39.8","Cell RNA - U-251 MG [nTPM]":"75.1","Cell RNA - U-266\/70 [nTPM]":"25.6","Cell RNA - U-266\/84 [nTPM]":"53.4","Cell RNA - U-698 [nTPM]":"44.1","Cell RNA - U-87 MG [nTPM]":"30.3","Cell RNA - U-937 [nTPM]":"80.7","Cell RNA - WM-115 [nTPM]":"34.7","Blood RNA - basophil [nTPM]":"1.8","Blood RNA - classical monocyte [nTPM]":"18.9","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"8.9","Blood RNA - intermediate monocyte [nTPM]":"15.0","Blood RNA - MAIT T-cell [nTPM]":"8.6","Blood RNA - memory B-cell [nTPM]":"12.4","Blood RNA - memory CD4 T-cell [nTPM]":"9.6","Blood RNA - memory CD8 T-cell [nTPM]":"8.6","Blood RNA - myeloid DC [nTPM]":"18.2","Blood RNA - naive B-cell [nTPM]":"12.9","Blood RNA - naive CD4 T-cell [nTPM]":"11.1","Blood RNA - naive CD8 T-cell [nTPM]":"8.5","Blood RNA - neutrophil [nTPM]":"3.7","Blood RNA - NK-cell [nTPM]":"5.6","Blood RNA - non-classical monocyte [nTPM]":"9.9","Blood RNA - plasmacytoid DC [nTPM]":"10.6","Blood RNA - T-reg [nTPM]":"6.9","Blood RNA - total PBMC [nTPM]":"10.7","Brain RNA - amygdala [nTPM]":"16.5","Brain RNA - basal ganglia [nTPM]":"15.3","Brain RNA - cerebellum [nTPM]":"14.7","Brain RNA - cerebral cortex [nTPM]":"22.1","Brain RNA - hippocampal formation [nTPM]":"15.5","Brain RNA - hypothalamus [nTPM]":"14.7","Brain RNA - medulla oblongata [nTPM]":"16.0","Brain RNA - midbrain [nTPM]":"14.8","Brain RNA - pons [nTPM]":"16.8","Brain RNA - spinal cord [nTPM]":"14.2","Brain RNA - thalamus [nTPM]":"16.2","Brain RNA - white matter [nTPM]":"17.6","Single Cell Type RNA - Adipocytes [nTPM]":"15.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.1","Single Cell Type RNA - Astrocytes [nTPM]":"8.5","Single Cell Type RNA - B-cells [nTPM]":"47.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"24.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.8","Single Cell Type RNA - Bipolar cells [nTPM]":"8.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"9.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"21.7","Single Cell Type RNA - dendritic cells [nTPM]":"19.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"17.3","Single Cell Type RNA - Early spermatids [nTPM]":"22.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.7","Single Cell Type RNA - Endothelial cells [nTPM]":"17.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"13.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"22.6","Single Cell Type RNA - Fibroblasts [nTPM]":"14.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.8","Single Cell Type RNA - granulocytes [nTPM]":"29.8","Single Cell Type RNA - Granulosa cells [nTPM]":"19.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"10.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"47.7","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.1","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"80.0","Single Cell Type RNA - Langerhans cells [nTPM]":"51.0","Single Cell Type RNA - Late spermatids [nTPM]":"47.9","Single Cell Type RNA - Leydig cells [nTPM]":"14.0","Single Cell Type RNA - Macrophages [nTPM]":"57.4","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"64.8","Single Cell Type RNA - Muller glia cells [nTPM]":"6.1","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.8","Single Cell Type RNA - Paneth cells [nTPM]":"6.8","Single Cell Type RNA - Peritubular cells [nTPM]":"12.8","Single Cell Type RNA - Plasma cells [nTPM]":"24.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"29.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.1","Single Cell Type RNA - Spermatocytes [nTPM]":"21.1","Single Cell Type RNA - Spermatogonia [nTPM]":"20.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.5","Single Cell Type RNA - T-cells [nTPM]":"24.4","Single Cell Type RNA - Theca cells [nTPM]":"14.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"22.5","Single Cell Type RNA - Urothelial cells [nTPM]":"20.3"},{"Gene":"TRMT10A","Gene synonym":["MGC27034","RG9MTD2","TRM10"],"Ensembl":"ENSG00000145331","Gene description":"TRNA methyltransferase 10A","Uniprot":["Q8TBZ6"],"Chromosome":"4","Position":"99546709-99564039","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":["Diabetes mellitus","Disease variant","Dwarfism","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"99.5","Spermatogonia":"55.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047601","HPA058241"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":["Nucleoplasm","Nucleoli","Actin filaments"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA047601":"AB_2680099","HPA058241":"AB_2683651"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.49e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.14e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.3","Tissue RNA - adrenal gland [nTPM]":"3.7","Tissue RNA - amygdala [nTPM]":"2.0","Tissue RNA - appendix [nTPM]":"3.1","Tissue RNA - basal ganglia [nTPM]":"2.6","Tissue RNA - bone marrow [nTPM]":"2.2","Tissue RNA - breast [nTPM]":"4.4","Tissue RNA - cerebellum [nTPM]":"2.6","Tissue RNA - cerebral cortex [nTPM]":"2.9","Tissue RNA - cervix [nTPM]":"1.9","Tissue RNA - choroid plexus [nTPM]":"1.5","Tissue RNA - colon [nTPM]":"3.6","Tissue RNA - duodenum [nTPM]":"4.3","Tissue RNA - endometrium 1 [nTPM]":"2.7","Tissue RNA - epididymis [nTPM]":"3.9","Tissue RNA - esophagus [nTPM]":"3.6","Tissue RNA - fallopian tube [nTPM]":"5.8","Tissue RNA - gallbladder [nTPM]":"3.4","Tissue RNA - heart muscle [nTPM]":"2.3","Tissue RNA - hippocampal formation [nTPM]":"1.8","Tissue RNA - hypothalamus [nTPM]":"2.5","Tissue RNA - kidney [nTPM]":"4.9","Tissue RNA - liver [nTPM]":"9.8","Tissue RNA - lung [nTPM]":"2.4","Tissue RNA - lymph node [nTPM]":"4.4","Tissue RNA - medulla oblongata [nTPM]":"2.6","Tissue RNA - midbrain [nTPM]":"2.5","Tissue RNA - ovary [nTPM]":"3.3","Tissue RNA - pancreas [nTPM]":"5.9","Tissue RNA - parathyroid gland [nTPM]":"3.7","Tissue RNA - pituitary gland [nTPM]":"2.3","Tissue RNA - placenta [nTPM]":"3.7","Tissue RNA - pons [nTPM]":"2.9","Tissue RNA - prostate [nTPM]":"4.1","Tissue RNA - rectum [nTPM]":"3.6","Tissue RNA - retina [nTPM]":"2.8","Tissue RNA - salivary gland [nTPM]":"3.9","Tissue RNA - seminal vesicle [nTPM]":"2.2","Tissue RNA - skeletal muscle [nTPM]":"3.9","Tissue RNA - skin 1 [nTPM]":"3.7","Tissue RNA - small intestine [nTPM]":"4.5","Tissue RNA - smooth muscle [nTPM]":"2.7","Tissue RNA - spinal cord [nTPM]":"2.7","Tissue RNA - spleen [nTPM]":"3.5","Tissue RNA - stomach 1 [nTPM]":"4.4","Tissue RNA - testis [nTPM]":"9.9","Tissue RNA - thalamus [nTPM]":"2.4","Tissue RNA - thymus [nTPM]":"4.3","Tissue RNA - thyroid gland [nTPM]":"6.1","Tissue RNA - tongue [nTPM]":"2.7","Tissue RNA - tonsil [nTPM]":"4.4","Tissue RNA - urinary bladder [nTPM]":"2.9","Tissue RNA - vagina [nTPM]":"2.0","Tissue RNA - white matter [nTPM]":"4.3","Cell RNA - A-431 [nTPM]":"8.2","Cell RNA - A549 [nTPM]":"5.4","Cell RNA - AF22 [nTPM]":"10.1","Cell RNA - AN3-CA [nTPM]":"5.7","Cell RNA - ASC diff [nTPM]":"6.0","Cell RNA - ASC TERT1 [nTPM]":"8.4","Cell RNA - BEWO [nTPM]":"7.8","Cell RNA - BJ [nTPM]":"9.6","Cell RNA - BJ hTERT+ [nTPM]":"3.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.1","Cell RNA - CACO-2 [nTPM]":"4.9","Cell RNA - CAPAN-2 [nTPM]":"9.4","Cell RNA - Daudi [nTPM]":"10.9","Cell RNA - EFO-21 [nTPM]":"3.7","Cell RNA - fHDF\/TERT166 [nTPM]":"5.6","Cell RNA - GAMG [nTPM]":"5.9","Cell RNA - HaCaT [nTPM]":"4.4","Cell RNA - HAP1 [nTPM]":"10.9","Cell RNA - HBEC3-KT [nTPM]":"5.1","Cell RNA - HBF TERT88 [nTPM]":"8.6","Cell RNA - HDLM-2 [nTPM]":"13.7","Cell RNA - HEK 293 [nTPM]":"5.4","Cell RNA - HEL [nTPM]":"8.0","Cell RNA - HeLa [nTPM]":"4.4","Cell RNA - Hep G2 [nTPM]":"7.6","Cell RNA - HHSteC [nTPM]":"5.5","Cell RNA - HL-60 [nTPM]":"19.6","Cell RNA - HMC-1 [nTPM]":"7.8","Cell RNA - HSkMC [nTPM]":"5.4","Cell RNA - hTCEpi [nTPM]":"14.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.7","Cell RNA - hTERT-HME1 [nTPM]":"14.0","Cell RNA - hTERT-RPE1 [nTPM]":"3.0","Cell RNA - HUVEC TERT2 [nTPM]":"6.4","Cell RNA - JURKAT [nTPM]":"10.0","Cell RNA - K-562 [nTPM]":"17.5","Cell RNA - Karpas-707 [nTPM]":"9.4","Cell RNA - LHCN-M2 [nTPM]":"4.5","Cell RNA - MCF7 [nTPM]":"9.4","Cell RNA - MOLT-4 [nTPM]":"16.4","Cell RNA - NB-4 [nTPM]":"3.5","Cell RNA - NTERA-2 [nTPM]":"6.5","Cell RNA - OE19 [nTPM]":"13.8","Cell RNA - PC-3 [nTPM]":"5.0","Cell RNA - REH [nTPM]":"9.5","Cell RNA - RH-30 [nTPM]":"10.2","Cell RNA - RPMI-8226 [nTPM]":"7.2","Cell RNA - RPTEC TERT1 [nTPM]":"8.5","Cell RNA - RT4 [nTPM]":"6.8","Cell RNA - SCLC-21H [nTPM]":"6.3","Cell RNA - SH-SY5Y [nTPM]":"5.8","Cell RNA - SiHa [nTPM]":"5.3","Cell RNA - SK-BR-3 [nTPM]":"28.3","Cell RNA - SK-MEL-30 [nTPM]":"9.9","Cell RNA - SuSa [nTPM]":"8.5","Cell RNA - T-47d [nTPM]":"9.3","Cell RNA - THP-1 [nTPM]":"7.8","Cell RNA - TIME [nTPM]":"4.9","Cell RNA - U-138 MG [nTPM]":"6.9","Cell RNA - U-2 OS [nTPM]":"7.2","Cell RNA - U-2197 [nTPM]":"5.5","Cell RNA - U-251 MG [nTPM]":"11.1","Cell RNA - U-266\/70 [nTPM]":"7.0","Cell RNA - U-266\/84 [nTPM]":"12.4","Cell RNA - U-698 [nTPM]":"10.0","Cell RNA - U-87 MG [nTPM]":"4.9","Cell RNA - U-937 [nTPM]":"10.9","Cell RNA - WM-115 [nTPM]":"4.7","Blood RNA - basophil [nTPM]":"2.7","Blood RNA - classical monocyte [nTPM]":"3.9","Blood RNA - eosinophil [nTPM]":"2.1","Blood RNA - gdT-cell [nTPM]":"1.8","Blood RNA - intermediate monocyte [nTPM]":"3.8","Blood RNA - MAIT T-cell [nTPM]":"1.7","Blood RNA - memory B-cell [nTPM]":"3.5","Blood RNA - memory CD4 T-cell [nTPM]":"3.3","Blood RNA - memory CD8 T-cell [nTPM]":"3.3","Blood RNA - myeloid DC [nTPM]":"5.2","Blood RNA - naive B-cell [nTPM]":"5.8","Blood RNA - naive CD4 T-cell [nTPM]":"3.5","Blood RNA - naive CD8 T-cell [nTPM]":"3.2","Blood RNA - neutrophil [nTPM]":"4.9","Blood RNA - NK-cell [nTPM]":"3.3","Blood RNA - non-classical monocyte [nTPM]":"3.4","Blood RNA - plasmacytoid DC [nTPM]":"3.0","Blood RNA - T-reg [nTPM]":"3.9","Blood RNA - total PBMC [nTPM]":"1.9","Brain RNA - amygdala [nTPM]":"2.0","Brain RNA - basal ganglia [nTPM]":"2.6","Brain RNA - cerebellum [nTPM]":"2.6","Brain RNA - cerebral cortex [nTPM]":"2.9","Brain RNA - hippocampal formation [nTPM]":"1.8","Brain RNA - hypothalamus [nTPM]":"2.5","Brain RNA - medulla oblongata [nTPM]":"2.6","Brain RNA - midbrain [nTPM]":"2.5","Brain RNA - pons [nTPM]":"2.9","Brain RNA - spinal cord [nTPM]":"2.7","Brain RNA - thalamus [nTPM]":"2.4","Brain RNA - white matter [nTPM]":"4.3","Single Cell Type RNA - Adipocytes [nTPM]":"7.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.3","Single Cell Type RNA - Astrocytes [nTPM]":"8.8","Single Cell Type RNA - B-cells [nTPM]":"8.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"4.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"6.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.8","Single Cell Type RNA - dendritic cells [nTPM]":"6.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"43.0","Single Cell Type RNA - Ductal cells [nTPM]":"13.8","Single Cell Type RNA - Early spermatids [nTPM]":"46.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"33.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.1","Single Cell Type RNA - Endothelial cells [nTPM]":"7.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"16.4","Single Cell Type RNA - Fibroblasts [nTPM]":"6.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.6","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"11.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.2","Single Cell Type RNA - Hepatocytes [nTPM]":"32.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.5","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.1","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"8.1","Single Cell Type RNA - Langerhans cells [nTPM]":"4.1","Single Cell Type RNA - Late spermatids [nTPM]":"17.0","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"5.0","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"8.4","Single Cell Type RNA - Muller glia cells [nTPM]":"8.7","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.1","Single Cell Type RNA - Paneth cells [nTPM]":"11.0","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"10.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"19.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"31.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.9","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.1","Single Cell Type RNA - Spermatocytes [nTPM]":"99.5","Single Cell Type RNA - Spermatogonia [nTPM]":"55.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.5","Single Cell Type RNA - T-cells [nTPM]":"5.5","Single Cell Type RNA - Theca cells [nTPM]":"8.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.6","Single Cell Type RNA - Urothelial cells [nTPM]":"6.6"},{"Gene":"TRMT10C","Gene synonym":["FLJ20432","MRPP1","RG9MTD1"],"Ensembl":"ENSG00000174173","Gene description":"TRNA methyltransferase 10C, mitochondrial RNase P subunit","Uniprot":["Q7L0Y3"],"Chromosome":"3","Position":"101561868-101566446","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["tRNA processing"],"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036671"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA036671":"AB_10602085"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.08e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.56e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.32e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Tissue RNA - adipose tissue [nTPM]":"16.6","Tissue RNA - adrenal gland [nTPM]":"17.4","Tissue RNA - amygdala [nTPM]":"6.9","Tissue RNA - appendix [nTPM]":"14.8","Tissue RNA - basal ganglia [nTPM]":"7.9","Tissue RNA - bone marrow [nTPM]":"18.2","Tissue RNA - breast [nTPM]":"20.8","Tissue RNA - cerebellum [nTPM]":"9.1","Tissue RNA - cerebral cortex [nTPM]":"9.7","Tissue RNA - cervix [nTPM]":"12.2","Tissue RNA - choroid plexus [nTPM]":"8.5","Tissue RNA - colon [nTPM]":"15.4","Tissue RNA - duodenum [nTPM]":"12.7","Tissue RNA - endometrium 1 [nTPM]":"14.1","Tissue RNA - epididymis [nTPM]":"13.4","Tissue RNA - esophagus [nTPM]":"18.9","Tissue RNA - fallopian tube [nTPM]":"14.5","Tissue RNA - gallbladder [nTPM]":"11.4","Tissue RNA - heart muscle [nTPM]":"21.6","Tissue RNA - hippocampal formation [nTPM]":"7.8","Tissue RNA - hypothalamus [nTPM]":"7.9","Tissue RNA - kidney [nTPM]":"19.2","Tissue RNA - liver [nTPM]":"25.2","Tissue RNA - lung [nTPM]":"10.3","Tissue RNA - lymph node [nTPM]":"20.5","Tissue RNA - medulla oblongata [nTPM]":"7.4","Tissue RNA - midbrain [nTPM]":"7.4","Tissue RNA - ovary [nTPM]":"15.7","Tissue RNA - pancreas [nTPM]":"10.4","Tissue RNA - parathyroid gland [nTPM]":"15.6","Tissue RNA - pituitary gland [nTPM]":"6.4","Tissue RNA - placenta [nTPM]":"14.0","Tissue RNA - pons [nTPM]":"7.9","Tissue RNA - prostate [nTPM]":"11.9","Tissue RNA - rectum [nTPM]":"14.7","Tissue RNA - retina [nTPM]":"7.8","Tissue RNA - salivary gland [nTPM]":"13.0","Tissue RNA - seminal vesicle [nTPM]":"9.9","Tissue RNA - skeletal muscle [nTPM]":"27.6","Tissue RNA - skin 1 [nTPM]":"12.7","Tissue RNA - small intestine [nTPM]":"13.1","Tissue RNA - smooth muscle [nTPM]":"16.0","Tissue RNA - spinal cord [nTPM]":"7.4","Tissue RNA - spleen [nTPM]":"12.5","Tissue RNA - stomach 1 [nTPM]":"12.1","Tissue RNA - testis [nTPM]":"11.8","Tissue RNA - thalamus [nTPM]":"7.5","Tissue RNA - thymus [nTPM]":"17.5","Tissue RNA - thyroid gland [nTPM]":"15.4","Tissue RNA - tongue [nTPM]":"30.2","Tissue RNA - tonsil [nTPM]":"20.7","Tissue RNA - urinary bladder [nTPM]":"26.6","Tissue RNA - vagina [nTPM]":"8.6","Tissue RNA - white matter [nTPM]":"7.5","Cell RNA - A-431 [nTPM]":"58.9","Cell RNA - A549 [nTPM]":"28.2","Cell RNA - AF22 [nTPM]":"36.6","Cell RNA - AN3-CA [nTPM]":"37.1","Cell RNA - ASC diff [nTPM]":"33.0","Cell RNA - ASC TERT1 [nTPM]":"28.0","Cell RNA - BEWO [nTPM]":"34.1","Cell RNA - BJ [nTPM]":"34.2","Cell RNA - BJ hTERT+ [nTPM]":"33.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"43.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"48.5","Cell RNA - CACO-2 [nTPM]":"43.2","Cell RNA - CAPAN-2 [nTPM]":"38.6","Cell RNA - Daudi [nTPM]":"121.3","Cell RNA - EFO-21 [nTPM]":"43.4","Cell RNA - fHDF\/TERT166 [nTPM]":"21.6","Cell RNA - GAMG [nTPM]":"35.4","Cell RNA - HaCaT [nTPM]":"57.9","Cell RNA - HAP1 [nTPM]":"71.5","Cell RNA - HBEC3-KT [nTPM]":"52.5","Cell RNA - HBF TERT88 [nTPM]":"59.7","Cell RNA - HDLM-2 [nTPM]":"43.8","Cell RNA - HEK 293 [nTPM]":"35.3","Cell RNA - HEL [nTPM]":"81.6","Cell RNA - HeLa [nTPM]":"20.5","Cell RNA - Hep G2 [nTPM]":"31.6","Cell RNA - HHSteC [nTPM]":"25.4","Cell RNA - HL-60 [nTPM]":"72.5","Cell RNA - HMC-1 [nTPM]":"33.1","Cell RNA - HSkMC [nTPM]":"32.9","Cell RNA - hTCEpi [nTPM]":"53.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"38.3","Cell RNA - hTERT-HME1 [nTPM]":"35.4","Cell RNA - hTERT-RPE1 [nTPM]":"23.2","Cell RNA - HUVEC TERT2 [nTPM]":"43.1","Cell RNA - JURKAT [nTPM]":"45.4","Cell RNA - K-562 [nTPM]":"70.3","Cell RNA - Karpas-707 [nTPM]":"26.3","Cell RNA - LHCN-M2 [nTPM]":"47.6","Cell RNA - MCF7 [nTPM]":"40.4","Cell RNA - MOLT-4 [nTPM]":"58.2","Cell RNA - NB-4 [nTPM]":"52.9","Cell RNA - NTERA-2 [nTPM]":"68.2","Cell RNA - OE19 [nTPM]":"75.9","Cell RNA - PC-3 [nTPM]":"60.4","Cell RNA - REH [nTPM]":"42.9","Cell RNA - RH-30 [nTPM]":"29.8","Cell RNA - RPMI-8226 [nTPM]":"54.3","Cell RNA - RPTEC TERT1 [nTPM]":"56.2","Cell RNA - RT4 [nTPM]":"49.0","Cell RNA - SCLC-21H [nTPM]":"90.9","Cell RNA - SH-SY5Y [nTPM]":"51.8","Cell RNA - SiHa [nTPM]":"26.7","Cell RNA - SK-BR-3 [nTPM]":"56.0","Cell RNA - SK-MEL-30 [nTPM]":"78.1","Cell RNA - SuSa [nTPM]":"31.9","Cell RNA - T-47d [nTPM]":"74.0","Cell RNA - THP-1 [nTPM]":"78.9","Cell RNA - TIME [nTPM]":"28.7","Cell RNA - U-138 MG [nTPM]":"23.6","Cell RNA - U-2 OS [nTPM]":"45.0","Cell RNA - U-2197 [nTPM]":"15.8","Cell RNA - U-251 MG [nTPM]":"36.5","Cell RNA - U-266\/70 [nTPM]":"30.4","Cell RNA - U-266\/84 [nTPM]":"59.4","Cell RNA - U-698 [nTPM]":"117.5","Cell RNA - U-87 MG [nTPM]":"40.0","Cell RNA - U-937 [nTPM]":"51.5","Cell RNA - WM-115 [nTPM]":"36.2","Blood RNA - basophil [nTPM]":"56.6","Blood RNA - classical monocyte [nTPM]":"18.2","Blood RNA - eosinophil [nTPM]":"12.8","Blood RNA - gdT-cell [nTPM]":"21.1","Blood RNA - intermediate monocyte [nTPM]":"24.7","Blood RNA - MAIT T-cell [nTPM]":"29.8","Blood RNA - memory B-cell [nTPM]":"35.7","Blood RNA - memory CD4 T-cell [nTPM]":"26.2","Blood RNA - memory CD8 T-cell [nTPM]":"25.1","Blood RNA - myeloid DC [nTPM]":"22.7","Blood RNA - naive B-cell [nTPM]":"34.2","Blood RNA - naive CD4 T-cell [nTPM]":"35.0","Blood RNA - naive CD8 T-cell [nTPM]":"33.2","Blood RNA - neutrophil [nTPM]":"8.1","Blood RNA - NK-cell [nTPM]":"21.4","Blood RNA - non-classical monocyte [nTPM]":"27.4","Blood RNA - plasmacytoid DC [nTPM]":"25.8","Blood RNA - T-reg [nTPM]":"26.2","Blood RNA - total PBMC [nTPM]":"19.5","Brain RNA - amygdala [nTPM]":"6.9","Brain RNA - basal ganglia [nTPM]":"7.9","Brain RNA - cerebellum [nTPM]":"9.1","Brain RNA - cerebral cortex [nTPM]":"9.7","Brain RNA - hippocampal formation [nTPM]":"7.8","Brain RNA - hypothalamus [nTPM]":"7.9","Brain RNA - medulla oblongata [nTPM]":"7.4","Brain RNA - midbrain [nTPM]":"7.4","Brain RNA - pons [nTPM]":"7.9","Brain RNA - spinal cord [nTPM]":"7.4","Brain RNA - thalamus [nTPM]":"7.5","Brain RNA - white matter [nTPM]":"7.5","Single Cell Type RNA - Adipocytes [nTPM]":"33.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"24.0","Single Cell Type RNA - Astrocytes [nTPM]":"4.9","Single Cell Type RNA - B-cells [nTPM]":"47.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"94.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"153.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"106.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"63.7","Single Cell Type RNA - Bipolar cells [nTPM]":"30.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"39.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"52.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"51.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"69.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"65.7","Single Cell Type RNA - dendritic cells [nTPM]":"50.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"21.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"52.8","Single Cell Type RNA - Ductal cells [nTPM]":"48.5","Single Cell Type RNA - Early spermatids [nTPM]":"49.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"54.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"54.0","Single Cell Type RNA - Endothelial cells [nTPM]":"39.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"35.8","Single Cell Type RNA - Erythroid cells [nTPM]":"65.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"33.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"47.0","Single Cell Type RNA - Fibroblasts [nTPM]":"38.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"28.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"63.5","Single Cell Type RNA - granulocytes [nTPM]":"46.3","Single Cell Type RNA - Granulosa cells [nTPM]":"47.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"31.4","Single Cell Type RNA - Hepatocytes [nTPM]":"56.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"31.1","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.5","Single Cell Type RNA - Ionocytes [nTPM]":"69.2","Single Cell Type RNA - Kupffer cells [nTPM]":"27.3","Single Cell Type RNA - Langerhans cells [nTPM]":"31.9","Single Cell Type RNA - Late spermatids [nTPM]":"13.7","Single Cell Type RNA - Leydig cells [nTPM]":"37.3","Single Cell Type RNA - Macrophages [nTPM]":"23.7","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"42.1","Single Cell Type RNA - Muller glia cells [nTPM]":"29.8","Single Cell Type RNA - NK-cells [nTPM]":"37.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"37.2","Single Cell Type RNA - Paneth cells [nTPM]":"17.9","Single Cell Type RNA - Peritubular cells [nTPM]":"37.6","Single Cell Type RNA - Plasma cells [nTPM]":"21.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"85.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"72.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"53.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"33.9","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"58.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"41.3","Single Cell Type RNA - Spermatocytes [nTPM]":"77.7","Single Cell Type RNA - Spermatogonia [nTPM]":"55.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"55.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"105.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"65.5","Single Cell Type RNA - T-cells [nTPM]":"46.4","Single Cell Type RNA - Theca cells [nTPM]":"57.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"47.0","Single Cell Type RNA - Urothelial cells [nTPM]":"127.4"},{"Gene":"TRMT5","Gene synonym":["KIAA1393","TRM5"],"Ensembl":"ENSG00000126814","Gene description":"TRNA methyltransferase 5","Uniprot":["Q32P41"],"Chromosome":"14","Position":"60971441-60981170","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["tRNA processing"],"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"221.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000943"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA000943":"AB_1080388"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.70e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.3","Tissue RNA - adrenal gland [nTPM]":"5.5","Tissue RNA - amygdala [nTPM]":"3.5","Tissue RNA - appendix [nTPM]":"4.4","Tissue RNA - basal ganglia [nTPM]":"3.8","Tissue RNA - bone marrow [nTPM]":"4.8","Tissue RNA - breast [nTPM]":"9.8","Tissue RNA - cerebellum [nTPM]":"6.0","Tissue RNA - cerebral cortex [nTPM]":"4.1","Tissue RNA - cervix [nTPM]":"6.5","Tissue RNA - choroid plexus [nTPM]":"3.1","Tissue RNA - colon [nTPM]":"6.7","Tissue RNA - duodenum [nTPM]":"5.7","Tissue RNA - endometrium 1 [nTPM]":"7.0","Tissue RNA - epididymis [nTPM]":"7.8","Tissue RNA - esophagus [nTPM]":"7.6","Tissue RNA - fallopian tube [nTPM]":"7.4","Tissue RNA - gallbladder [nTPM]":"5.1","Tissue RNA - heart muscle [nTPM]":"4.2","Tissue RNA - hippocampal formation [nTPM]":"3.4","Tissue RNA - hypothalamus [nTPM]":"4.6","Tissue RNA - kidney [nTPM]":"6.9","Tissue RNA - liver [nTPM]":"6.8","Tissue RNA - lung [nTPM]":"5.0","Tissue RNA - lymph node [nTPM]":"6.0","Tissue RNA - medulla oblongata [nTPM]":"2.5","Tissue RNA - midbrain [nTPM]":"3.4","Tissue RNA - ovary [nTPM]":"9.9","Tissue RNA - pancreas [nTPM]":"6.7","Tissue RNA - parathyroid gland [nTPM]":"10.5","Tissue RNA - pituitary gland [nTPM]":"3.5","Tissue RNA - placenta [nTPM]":"7.0","Tissue RNA - pons [nTPM]":"2.8","Tissue RNA - prostate [nTPM]":"6.9","Tissue RNA - rectum [nTPM]":"6.0","Tissue RNA - retina [nTPM]":"5.2","Tissue RNA - salivary gland [nTPM]":"7.6","Tissue RNA - seminal vesicle [nTPM]":"4.8","Tissue RNA - skeletal muscle [nTPM]":"7.5","Tissue RNA - skin 1 [nTPM]":"6.7","Tissue RNA - small intestine [nTPM]":"4.5","Tissue RNA - smooth muscle [nTPM]":"7.0","Tissue RNA - spinal cord [nTPM]":"3.1","Tissue RNA - spleen [nTPM]":"4.7","Tissue RNA - stomach 1 [nTPM]":"5.8","Tissue RNA - testis [nTPM]":"17.3","Tissue RNA - thalamus [nTPM]":"4.0","Tissue RNA - thymus [nTPM]":"6.1","Tissue RNA - thyroid gland [nTPM]":"7.2","Tissue RNA - tongue [nTPM]":"7.2","Tissue RNA - tonsil [nTPM]":"5.8","Tissue RNA - urinary bladder [nTPM]":"6.7","Tissue RNA - vagina [nTPM]":"3.9","Tissue RNA - white matter [nTPM]":"3.8","Cell RNA - A-431 [nTPM]":"49.7","Cell RNA - A549 [nTPM]":"12.5","Cell RNA - AF22 [nTPM]":"17.9","Cell RNA - AN3-CA [nTPM]":"25.0","Cell RNA - ASC diff [nTPM]":"15.5","Cell RNA - ASC TERT1 [nTPM]":"23.6","Cell RNA - BEWO [nTPM]":"19.4","Cell RNA - BJ [nTPM]":"18.2","Cell RNA - BJ hTERT+ [nTPM]":"14.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.2","Cell RNA - CACO-2 [nTPM]":"9.8","Cell RNA - CAPAN-2 [nTPM]":"28.7","Cell RNA - Daudi [nTPM]":"25.2","Cell RNA - EFO-21 [nTPM]":"19.9","Cell RNA - fHDF\/TERT166 [nTPM]":"13.3","Cell RNA - GAMG [nTPM]":"14.3","Cell RNA - HaCaT [nTPM]":"22.3","Cell RNA - HAP1 [nTPM]":"22.9","Cell RNA - HBEC3-KT [nTPM]":"26.4","Cell RNA - HBF TERT88 [nTPM]":"25.0","Cell RNA - HDLM-2 [nTPM]":"25.3","Cell RNA - HEK 293 [nTPM]":"11.5","Cell RNA - HEL [nTPM]":"18.6","Cell RNA - HeLa [nTPM]":"8.1","Cell RNA - Hep G2 [nTPM]":"10.2","Cell RNA - HHSteC [nTPM]":"25.1","Cell RNA - HL-60 [nTPM]":"33.2","Cell RNA - HMC-1 [nTPM]":"9.9","Cell RNA - HSkMC [nTPM]":"18.3","Cell RNA - hTCEpi [nTPM]":"25.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"17.4","Cell RNA - hTERT-HME1 [nTPM]":"25.4","Cell RNA - hTERT-RPE1 [nTPM]":"17.0","Cell RNA - HUVEC TERT2 [nTPM]":"17.0","Cell RNA - JURKAT [nTPM]":"21.6","Cell RNA - K-562 [nTPM]":"24.5","Cell RNA - Karpas-707 [nTPM]":"8.8","Cell RNA - LHCN-M2 [nTPM]":"28.3","Cell RNA - MCF7 [nTPM]":"18.7","Cell RNA - MOLT-4 [nTPM]":"17.1","Cell RNA - NB-4 [nTPM]":"16.8","Cell RNA - NTERA-2 [nTPM]":"16.4","Cell RNA - OE19 [nTPM]":"19.4","Cell RNA - PC-3 [nTPM]":"20.3","Cell RNA - REH [nTPM]":"5.4","Cell RNA - RH-30 [nTPM]":"41.5","Cell RNA - RPMI-8226 [nTPM]":"21.4","Cell RNA - RPTEC TERT1 [nTPM]":"16.3","Cell RNA - RT4 [nTPM]":"16.7","Cell RNA - SCLC-21H [nTPM]":"22.1","Cell RNA - SH-SY5Y [nTPM]":"21.6","Cell RNA - SiHa [nTPM]":"20.2","Cell RNA - SK-BR-3 [nTPM]":"20.1","Cell RNA - SK-MEL-30 [nTPM]":"16.6","Cell RNA - SuSa [nTPM]":"15.4","Cell RNA - T-47d [nTPM]":"33.5","Cell RNA - THP-1 [nTPM]":"19.7","Cell RNA - TIME [nTPM]":"16.1","Cell RNA - U-138 MG [nTPM]":"22.1","Cell RNA - U-2 OS [nTPM]":"26.7","Cell RNA - U-2197 [nTPM]":"15.7","Cell RNA - U-251 MG [nTPM]":"17.5","Cell RNA - U-266\/70 [nTPM]":"5.3","Cell RNA - U-266\/84 [nTPM]":"10.8","Cell RNA - U-698 [nTPM]":"11.6","Cell RNA - U-87 MG [nTPM]":"15.6","Cell RNA - U-937 [nTPM]":"7.2","Cell RNA - WM-115 [nTPM]":"21.0","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"3.2","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"2.4","Blood RNA - intermediate monocyte [nTPM]":"5.5","Blood RNA - MAIT T-cell [nTPM]":"3.3","Blood RNA - memory B-cell [nTPM]":"4.9","Blood RNA - memory CD4 T-cell [nTPM]":"3.4","Blood RNA - memory CD8 T-cell [nTPM]":"3.5","Blood RNA - myeloid DC [nTPM]":"3.0","Blood RNA - naive B-cell [nTPM]":"4.1","Blood RNA - naive CD4 T-cell [nTPM]":"3.8","Blood RNA - naive CD8 T-cell [nTPM]":"3.4","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"1.4","Blood RNA - non-classical monocyte [nTPM]":"5.9","Blood RNA - plasmacytoid DC [nTPM]":"5.2","Blood RNA - T-reg [nTPM]":"4.5","Blood RNA - total PBMC [nTPM]":"2.5","Brain RNA - amygdala [nTPM]":"3.5","Brain RNA - basal ganglia [nTPM]":"3.8","Brain RNA - cerebellum [nTPM]":"6.0","Brain RNA - cerebral cortex [nTPM]":"4.1","Brain RNA - hippocampal formation [nTPM]":"3.4","Brain RNA - hypothalamus [nTPM]":"4.6","Brain RNA - medulla oblongata [nTPM]":"2.5","Brain RNA - midbrain [nTPM]":"3.4","Brain RNA - pons [nTPM]":"2.8","Brain RNA - spinal cord [nTPM]":"3.1","Brain RNA - thalamus [nTPM]":"4.0","Brain RNA - white matter [nTPM]":"3.8","Single Cell Type RNA - Adipocytes [nTPM]":"7.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.9","Single Cell Type RNA - Astrocytes [nTPM]":"3.9","Single Cell Type RNA - B-cells [nTPM]":"4.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"19.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"5.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"19.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.8","Single Cell Type RNA - dendritic cells [nTPM]":"5.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.7","Single Cell Type RNA - Early spermatids [nTPM]":"221.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.4","Single Cell Type RNA - Endothelial cells [nTPM]":"9.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"10.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.4","Single Cell Type RNA - Fibroblasts [nTPM]":"12.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.1","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"12.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.6","Single Cell Type RNA - Hepatocytes [nTPM]":"7.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.9","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.3","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"6.2","Single Cell Type RNA - Langerhans cells [nTPM]":"7.6","Single Cell Type RNA - Late spermatids [nTPM]":"50.2","Single Cell Type RNA - Leydig cells [nTPM]":"11.1","Single Cell Type RNA - Macrophages [nTPM]":"6.0","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"4.1","Single Cell Type RNA - Muller glia cells [nTPM]":"12.2","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.2","Single Cell Type RNA - Paneth cells [nTPM]":"4.8","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"4.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.4","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.5","Single Cell Type RNA - Spermatocytes [nTPM]":"23.3","Single Cell Type RNA - Spermatogonia [nTPM]":"12.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"19.2","Single Cell Type RNA - T-cells [nTPM]":"5.2","Single Cell Type RNA - Theca cells [nTPM]":"14.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.6","Single Cell Type RNA - Urothelial cells [nTPM]":"10.6"},{"Gene":"TRMU","Gene synonym":["FLJ10140","MTO2","MTU1","TRMT"],"Ensembl":"ENSG00000100416","Gene description":"TRNA mitochondrial 2-thiouridylase","Uniprot":["O75648"],"Chromosome":"22","Position":"46330875-46357340","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["tRNA processing"],"Molecular function":["RNA-binding","Transferase","tRNA-binding"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000824","HPA035273","HPA043300"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA000824":"AB_2732393","HPA035273":"AB_10602901","HPA043300":"AB_2678415"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.04e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.86e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.63e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.44e-3"},"Tissue RNA - adipose tissue [nTPM]":"4.2","Tissue RNA - adrenal gland [nTPM]":"7.5","Tissue RNA - amygdala [nTPM]":"7.7","Tissue RNA - appendix [nTPM]":"2.3","Tissue RNA - basal ganglia [nTPM]":"7.8","Tissue RNA - bone marrow [nTPM]":"2.9","Tissue RNA - breast [nTPM]":"4.0","Tissue RNA - cerebellum [nTPM]":"8.3","Tissue RNA - cerebral cortex [nTPM]":"9.6","Tissue RNA - cervix [nTPM]":"4.3","Tissue RNA - choroid plexus [nTPM]":"8.3","Tissue RNA - colon [nTPM]":"4.5","Tissue RNA - duodenum [nTPM]":"4.7","Tissue RNA - endometrium 1 [nTPM]":"3.6","Tissue RNA - epididymis [nTPM]":"7.5","Tissue RNA - esophagus [nTPM]":"5.6","Tissue RNA - fallopian tube [nTPM]":"3.4","Tissue RNA - gallbladder [nTPM]":"2.6","Tissue RNA - heart muscle [nTPM]":"11.2","Tissue RNA - hippocampal formation [nTPM]":"7.6","Tissue RNA - hypothalamus [nTPM]":"8.5","Tissue RNA - kidney [nTPM]":"9.1","Tissue RNA - liver [nTPM]":"8.8","Tissue RNA - lung [nTPM]":"3.5","Tissue RNA - lymph node [nTPM]":"5.0","Tissue RNA - medulla oblongata [nTPM]":"8.5","Tissue RNA - midbrain [nTPM]":"8.6","Tissue RNA - ovary [nTPM]":"4.0","Tissue RNA - pancreas [nTPM]":"10.2","Tissue RNA - parathyroid gland [nTPM]":"8.0","Tissue RNA - pituitary gland [nTPM]":"5.3","Tissue RNA - placenta [nTPM]":"4.1","Tissue RNA - pons [nTPM]":"8.5","Tissue RNA - prostate [nTPM]":"4.4","Tissue RNA - rectum [nTPM]":"4.1","Tissue RNA - retina [nTPM]":"2.8","Tissue RNA - salivary gland [nTPM]":"5.5","Tissue RNA - seminal vesicle [nTPM]":"4.7","Tissue RNA - skeletal muscle [nTPM]":"6.9","Tissue RNA - skin 1 [nTPM]":"4.8","Tissue RNA - small intestine [nTPM]":"4.0","Tissue RNA - smooth muscle [nTPM]":"3.9","Tissue RNA - spinal cord [nTPM]":"7.9","Tissue RNA - spleen [nTPM]":"4.2","Tissue RNA - stomach 1 [nTPM]":"4.3","Tissue RNA - testis [nTPM]":"2.3","Tissue RNA - thalamus [nTPM]":"8.5","Tissue RNA - thymus [nTPM]":"3.0","Tissue RNA - thyroid gland [nTPM]":"4.6","Tissue RNA - tongue [nTPM]":"8.4","Tissue RNA - tonsil [nTPM]":"4.3","Tissue RNA - urinary bladder [nTPM]":"4.2","Tissue RNA - vagina [nTPM]":"4.1","Tissue RNA - white matter [nTPM]":"7.8","Cell RNA - A-431 [nTPM]":"17.8","Cell RNA - A549 [nTPM]":"16.0","Cell RNA - AF22 [nTPM]":"6.6","Cell RNA - AN3-CA [nTPM]":"15.1","Cell RNA - ASC diff [nTPM]":"12.2","Cell RNA - ASC TERT1 [nTPM]":"8.6","Cell RNA - BEWO [nTPM]":"16.6","Cell RNA - BJ [nTPM]":"18.1","Cell RNA - BJ hTERT+ [nTPM]":"12.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.2","Cell RNA - CACO-2 [nTPM]":"22.7","Cell RNA - CAPAN-2 [nTPM]":"4.5","Cell RNA - Daudi [nTPM]":"11.5","Cell RNA - EFO-21 [nTPM]":"12.5","Cell RNA - fHDF\/TERT166 [nTPM]":"16.2","Cell RNA - GAMG [nTPM]":"10.9","Cell RNA - HaCaT [nTPM]":"15.3","Cell RNA - HAP1 [nTPM]":"28.5","Cell RNA - HBEC3-KT [nTPM]":"16.0","Cell RNA - HBF TERT88 [nTPM]":"21.1","Cell RNA - HDLM-2 [nTPM]":"7.5","Cell RNA - HEK 293 [nTPM]":"38.4","Cell RNA - HEL [nTPM]":"13.6","Cell RNA - HeLa [nTPM]":"25.0","Cell RNA - Hep G2 [nTPM]":"27.1","Cell RNA - HHSteC [nTPM]":"10.4","Cell RNA - HL-60 [nTPM]":"26.5","Cell RNA - HMC-1 [nTPM]":"9.0","Cell RNA - HSkMC [nTPM]":"8.2","Cell RNA - hTCEpi [nTPM]":"17.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.8","Cell RNA - hTERT-HME1 [nTPM]":"8.1","Cell RNA - hTERT-RPE1 [nTPM]":"10.3","Cell RNA - HUVEC TERT2 [nTPM]":"16.2","Cell RNA - JURKAT [nTPM]":"5.8","Cell RNA - K-562 [nTPM]":"19.3","Cell RNA - Karpas-707 [nTPM]":"2.7","Cell RNA - LHCN-M2 [nTPM]":"15.3","Cell RNA - MCF7 [nTPM]":"19.1","Cell RNA - MOLT-4 [nTPM]":"10.4","Cell RNA - NB-4 [nTPM]":"21.5","Cell RNA - NTERA-2 [nTPM]":"25.5","Cell RNA - OE19 [nTPM]":"10.6","Cell RNA - PC-3 [nTPM]":"27.5","Cell RNA - REH [nTPM]":"12.2","Cell RNA - RH-30 [nTPM]":"14.4","Cell RNA - RPMI-8226 [nTPM]":"21.2","Cell RNA - RPTEC TERT1 [nTPM]":"12.5","Cell RNA - RT4 [nTPM]":"12.1","Cell RNA - SCLC-21H [nTPM]":"15.9","Cell RNA - SH-SY5Y [nTPM]":"19.0","Cell RNA - SiHa [nTPM]":"16.0","Cell RNA - SK-BR-3 [nTPM]":"18.5","Cell RNA - SK-MEL-30 [nTPM]":"31.7","Cell RNA - SuSa [nTPM]":"8.2","Cell RNA - T-47d [nTPM]":"10.7","Cell RNA - THP-1 [nTPM]":"10.9","Cell RNA - TIME [nTPM]":"11.9","Cell RNA - U-138 MG [nTPM]":"11.1","Cell RNA - U-2 OS [nTPM]":"19.8","Cell RNA - U-2197 [nTPM]":"15.8","Cell RNA - U-251 MG [nTPM]":"20.7","Cell RNA - U-266\/70 [nTPM]":"6.5","Cell RNA - U-266\/84 [nTPM]":"7.8","Cell RNA - U-698 [nTPM]":"12.6","Cell RNA - U-87 MG [nTPM]":"15.7","Cell RNA - U-937 [nTPM]":"19.1","Cell RNA - WM-115 [nTPM]":"22.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"6.2","Blood RNA - eosinophil [nTPM]":"3.8","Blood RNA - gdT-cell [nTPM]":"9.4","Blood RNA - intermediate monocyte [nTPM]":"9.0","Blood RNA - MAIT T-cell [nTPM]":"8.3","Blood RNA - memory B-cell [nTPM]":"5.4","Blood RNA - memory CD4 T-cell [nTPM]":"8.2","Blood RNA - memory CD8 T-cell [nTPM]":"8.9","Blood RNA - myeloid DC [nTPM]":"7.1","Blood RNA - naive B-cell [nTPM]":"5.5","Blood RNA - naive CD4 T-cell [nTPM]":"7.3","Blood RNA - naive CD8 T-cell [nTPM]":"6.9","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"8.0","Blood RNA - non-classical monocyte [nTPM]":"9.8","Blood RNA - plasmacytoid DC [nTPM]":"5.8","Blood RNA - T-reg [nTPM]":"11.0","Blood RNA - total PBMC [nTPM]":"5.9","Brain RNA - amygdala [nTPM]":"7.7","Brain RNA - basal ganglia [nTPM]":"7.8","Brain RNA - cerebellum [nTPM]":"8.3","Brain RNA - cerebral cortex [nTPM]":"9.6","Brain RNA - hippocampal formation [nTPM]":"7.6","Brain RNA - hypothalamus [nTPM]":"8.5","Brain RNA - medulla oblongata [nTPM]":"8.5","Brain RNA - midbrain [nTPM]":"8.6","Brain RNA - pons [nTPM]":"8.5","Brain RNA - spinal cord [nTPM]":"7.9","Brain RNA - thalamus [nTPM]":"8.5","Brain RNA - white matter [nTPM]":"7.8","Single Cell Type RNA - Adipocytes [nTPM]":"12.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.1","Single Cell Type RNA - Astrocytes [nTPM]":"22.9","Single Cell Type RNA - B-cells [nTPM]":"13.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"26.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"10.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"24.9","Single Cell Type RNA - dendritic cells [nTPM]":"16.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"27.4","Single Cell Type RNA - Ductal cells [nTPM]":"20.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.2","Single Cell Type RNA - Endothelial cells [nTPM]":"14.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.5","Single Cell Type RNA - Erythroid cells [nTPM]":"14.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.0","Single Cell Type RNA - Fibroblasts [nTPM]":"11.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.6","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"26.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.9","Single Cell Type RNA - Hepatocytes [nTPM]":"16.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.9","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.3","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"9.9","Single Cell Type RNA - Langerhans cells [nTPM]":"4.0","Single Cell Type RNA - Late spermatids [nTPM]":"3.3","Single Cell Type RNA - Leydig cells [nTPM]":"15.2","Single Cell Type RNA - Macrophages [nTPM]":"8.8","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"14.9","Single Cell Type RNA - Muller glia cells [nTPM]":"11.9","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.5","Single Cell Type RNA - Paneth cells [nTPM]":"9.9","Single Cell Type RNA - Peritubular cells [nTPM]":"17.0","Single Cell Type RNA - Plasma cells [nTPM]":"13.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"27.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"26.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.4","Single Cell Type RNA - Spermatocytes [nTPM]":"18.5","Single Cell Type RNA - Spermatogonia [nTPM]":"12.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.3","Single Cell Type RNA - T-cells [nTPM]":"13.1","Single Cell Type RNA - Theca cells [nTPM]":"21.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.3","Single Cell Type RNA - Urothelial cells [nTPM]":"9.9"},{"Gene":"TRNT1","Gene synonym":["CCA1","CGI-47","MtCCA"],"Ensembl":"ENSG00000072756","Gene description":"TRNA nucleotidyl transferase 1","Uniprot":["Q96Q11"],"Chromosome":"3","Position":"3126933-3150879","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["tRNA processing"],"Molecular function":["Nucleotidyltransferase","RNA-binding","Transferase"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036938"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA036938":"AB_10670566"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.7","Tissue RNA - adrenal gland [nTPM]":"10.0","Tissue RNA - amygdala [nTPM]":"7.2","Tissue RNA - appendix [nTPM]":"8.9","Tissue RNA - basal ganglia [nTPM]":"7.2","Tissue RNA - bone marrow [nTPM]":"3.5","Tissue RNA - breast [nTPM]":"8.5","Tissue RNA - cerebellum [nTPM]":"7.9","Tissue RNA - cerebral cortex [nTPM]":"8.0","Tissue RNA - cervix [nTPM]":"7.8","Tissue RNA - choroid plexus [nTPM]":"7.0","Tissue RNA - colon [nTPM]":"8.1","Tissue RNA - duodenum [nTPM]":"4.4","Tissue RNA - endometrium 1 [nTPM]":"8.8","Tissue RNA - epididymis [nTPM]":"5.5","Tissue RNA - esophagus [nTPM]":"9.4","Tissue RNA - fallopian tube [nTPM]":"7.6","Tissue RNA - gallbladder [nTPM]":"8.3","Tissue RNA - heart muscle [nTPM]":"8.4","Tissue RNA - hippocampal formation [nTPM]":"7.4","Tissue RNA - hypothalamus [nTPM]":"7.2","Tissue RNA - kidney [nTPM]":"17.2","Tissue RNA - liver [nTPM]":"10.0","Tissue RNA - lung [nTPM]":"8.4","Tissue RNA - lymph node [nTPM]":"9.7","Tissue RNA - medulla oblongata [nTPM]":"7.1","Tissue RNA - midbrain [nTPM]":"7.3","Tissue RNA - ovary [nTPM]":"8.3","Tissue RNA - pancreas [nTPM]":"8.4","Tissue RNA - parathyroid gland [nTPM]":"8.3","Tissue RNA - pituitary gland [nTPM]":"10.3","Tissue RNA - placenta [nTPM]":"10.5","Tissue RNA - pons [nTPM]":"7.1","Tissue RNA - prostate [nTPM]":"11.3","Tissue RNA - rectum [nTPM]":"7.6","Tissue RNA - retina [nTPM]":"4.0","Tissue RNA - salivary gland [nTPM]":"7.7","Tissue RNA - seminal vesicle [nTPM]":"6.3","Tissue RNA - skeletal muscle [nTPM]":"9.3","Tissue RNA - skin 1 [nTPM]":"6.4","Tissue RNA - small intestine [nTPM]":"7.9","Tissue RNA - smooth muscle [nTPM]":"8.3","Tissue RNA - spinal cord [nTPM]":"7.3","Tissue RNA - spleen [nTPM]":"10.7","Tissue RNA - stomach 1 [nTPM]":"9.1","Tissue RNA - testis [nTPM]":"6.5","Tissue RNA - thalamus [nTPM]":"7.4","Tissue RNA - thymus [nTPM]":"9.8","Tissue RNA - thyroid gland [nTPM]":"11.3","Tissue RNA - tongue [nTPM]":"7.6","Tissue RNA - tonsil [nTPM]":"10.9","Tissue RNA - urinary bladder [nTPM]":"13.1","Tissue RNA - vagina [nTPM]":"7.9","Tissue RNA - white matter [nTPM]":"8.0","Cell RNA - A-431 [nTPM]":"20.0","Cell RNA - A549 [nTPM]":"29.6","Cell RNA - AF22 [nTPM]":"18.2","Cell RNA - AN3-CA [nTPM]":"9.8","Cell RNA - ASC diff [nTPM]":"24.1","Cell RNA - ASC TERT1 [nTPM]":"21.5","Cell RNA - BEWO [nTPM]":"20.5","Cell RNA - BJ [nTPM]":"19.9","Cell RNA - BJ hTERT+ [nTPM]":"17.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.9","Cell RNA - CACO-2 [nTPM]":"25.0","Cell RNA - CAPAN-2 [nTPM]":"20.9","Cell RNA - Daudi [nTPM]":"35.6","Cell RNA - EFO-21 [nTPM]":"12.8","Cell RNA - fHDF\/TERT166 [nTPM]":"22.4","Cell RNA - GAMG [nTPM]":"32.0","Cell RNA - HaCaT [nTPM]":"12.6","Cell RNA - HAP1 [nTPM]":"24.6","Cell RNA - HBEC3-KT [nTPM]":"18.6","Cell RNA - HBF TERT88 [nTPM]":"26.5","Cell RNA - HDLM-2 [nTPM]":"24.6","Cell RNA - HEK 293 [nTPM]":"13.3","Cell RNA - HEL [nTPM]":"28.7","Cell RNA - HeLa [nTPM]":"25.3","Cell RNA - Hep G2 [nTPM]":"24.9","Cell RNA - HHSteC [nTPM]":"31.4","Cell RNA - HL-60 [nTPM]":"32.2","Cell RNA - HMC-1 [nTPM]":"20.8","Cell RNA - HSkMC [nTPM]":"17.9","Cell RNA - hTCEpi [nTPM]":"25.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.2","Cell RNA - hTERT-HME1 [nTPM]":"6.8","Cell RNA - hTERT-RPE1 [nTPM]":"15.0","Cell RNA - HUVEC TERT2 [nTPM]":"21.0","Cell RNA - JURKAT [nTPM]":"24.1","Cell RNA - K-562 [nTPM]":"25.1","Cell RNA - Karpas-707 [nTPM]":"9.8","Cell RNA - LHCN-M2 [nTPM]":"35.9","Cell RNA - MCF7 [nTPM]":"37.2","Cell RNA - MOLT-4 [nTPM]":"22.0","Cell RNA - NB-4 [nTPM]":"21.4","Cell RNA - NTERA-2 [nTPM]":"15.2","Cell RNA - OE19 [nTPM]":"29.2","Cell RNA - PC-3 [nTPM]":"19.0","Cell RNA - REH [nTPM]":"20.5","Cell RNA - RH-30 [nTPM]":"28.1","Cell RNA - RPMI-8226 [nTPM]":"32.5","Cell RNA - RPTEC TERT1 [nTPM]":"26.1","Cell RNA - RT4 [nTPM]":"25.8","Cell RNA - SCLC-21H [nTPM]":"10.8","Cell RNA - SH-SY5Y [nTPM]":"15.9","Cell RNA - SiHa [nTPM]":"31.6","Cell RNA - SK-BR-3 [nTPM]":"20.6","Cell RNA - SK-MEL-30 [nTPM]":"18.5","Cell RNA - SuSa [nTPM]":"26.3","Cell RNA - T-47d [nTPM]":"18.7","Cell RNA - THP-1 [nTPM]":"16.3","Cell RNA - TIME [nTPM]":"14.8","Cell RNA - U-138 MG [nTPM]":"22.8","Cell RNA - U-2 OS [nTPM]":"18.7","Cell RNA - U-2197 [nTPM]":"23.6","Cell RNA - U-251 MG [nTPM]":"25.7","Cell RNA - U-266\/70 [nTPM]":"12.6","Cell RNA - U-266\/84 [nTPM]":"31.4","Cell RNA - U-698 [nTPM]":"43.4","Cell RNA - U-87 MG [nTPM]":"17.2","Cell RNA - U-937 [nTPM]":"27.6","Cell RNA - WM-115 [nTPM]":"25.0","Blood RNA - basophil [nTPM]":"49.4","Blood RNA - classical monocyte [nTPM]":"12.4","Blood RNA - eosinophil [nTPM]":"36.4","Blood RNA - gdT-cell [nTPM]":"16.4","Blood RNA - intermediate monocyte [nTPM]":"18.1","Blood RNA - MAIT T-cell [nTPM]":"16.0","Blood RNA - memory B-cell [nTPM]":"25.8","Blood RNA - memory CD4 T-cell [nTPM]":"20.8","Blood RNA - memory CD8 T-cell [nTPM]":"18.1","Blood RNA - myeloid DC [nTPM]":"16.8","Blood RNA - naive B-cell [nTPM]":"15.7","Blood RNA - naive CD4 T-cell [nTPM]":"22.7","Blood RNA - naive CD8 T-cell [nTPM]":"20.1","Blood RNA - neutrophil [nTPM]":"16.6","Blood RNA - NK-cell [nTPM]":"19.8","Blood RNA - non-classical monocyte [nTPM]":"19.0","Blood RNA - plasmacytoid DC [nTPM]":"15.6","Blood RNA - T-reg [nTPM]":"18.6","Blood RNA - total PBMC [nTPM]":"11.2","Brain RNA - amygdala [nTPM]":"7.2","Brain RNA - basal ganglia [nTPM]":"7.2","Brain RNA - cerebellum [nTPM]":"7.9","Brain RNA - cerebral cortex [nTPM]":"8.0","Brain RNA - hippocampal formation [nTPM]":"7.4","Brain RNA - hypothalamus [nTPM]":"7.2","Brain RNA - medulla oblongata [nTPM]":"7.1","Brain RNA - midbrain [nTPM]":"7.3","Brain RNA - pons [nTPM]":"7.1","Brain RNA - spinal cord [nTPM]":"7.3","Brain RNA - thalamus [nTPM]":"7.4","Brain RNA - white matter [nTPM]":"8.0","Single Cell Type RNA - Adipocytes [nTPM]":"20.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.4","Single Cell Type RNA - Astrocytes [nTPM]":"15.3","Single Cell Type RNA - B-cells [nTPM]":"30.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"29.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"19.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"13.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"16.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.8","Single Cell Type RNA - dendritic cells [nTPM]":"23.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"45.0","Single Cell Type RNA - Ductal cells [nTPM]":"19.1","Single Cell Type RNA - Early spermatids [nTPM]":"2.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.0","Single Cell Type RNA - Endothelial cells [nTPM]":"21.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"16.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.8","Single Cell Type RNA - Fibroblasts [nTPM]":"19.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.0","Single Cell Type RNA - granulocytes [nTPM]":"22.8","Single Cell Type RNA - Granulosa cells [nTPM]":"20.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.5","Single Cell Type RNA - Hepatocytes [nTPM]":"9.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.3","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"27.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.7","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"11.0","Single Cell Type RNA - Langerhans cells [nTPM]":"13.3","Single Cell Type RNA - Late spermatids [nTPM]":"2.9","Single Cell Type RNA - Leydig cells [nTPM]":"10.8","Single Cell Type RNA - Macrophages [nTPM]":"13.3","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"20.3","Single Cell Type RNA - Muller glia cells [nTPM]":"17.1","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"23.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"34.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.6","Single Cell Type RNA - Paneth cells [nTPM]":"9.2","Single Cell Type RNA - Peritubular cells [nTPM]":"8.6","Single Cell Type RNA - Plasma cells [nTPM]":"30.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"32.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.4","Single Cell Type RNA - Spermatocytes [nTPM]":"20.8","Single Cell Type RNA - Spermatogonia [nTPM]":"17.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"28.3","Single Cell Type RNA - T-cells [nTPM]":"22.0","Single Cell Type RNA - Theca cells [nTPM]":"24.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.5","Single Cell Type RNA - Urothelial cells [nTPM]":"23.9"},{"Gene":"TRPC3","Gene synonym":[],"Ensembl":"ENSG00000138741","Gene description":"Transient receptor potential cation channel subfamily C member 3","Uniprot":["Q13507"],"Chromosome":"4","Position":"121874481-121952060","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel"],"Disease involvement":["Disease variant","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"10.4","pituitary gland":"7.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"18.1","Inhibitory neurons":"82.7","Oligodendrocyte precursor cells":"33.7","Rod photoreceptor cells":"32.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"2.3","Karpas-707":"2.6","U-2 OS":"1.5","U-251 MG":"1.5"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebellum":"57.8"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"2.3","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"4.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"4.6","Tissue RNA - cerebral cortex [nTPM]":"5.8","Tissue RNA - cervix [nTPM]":"0.8","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.8","Tissue RNA - hypothalamus [nTPM]":"3.2","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.9","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"10.4","Tissue RNA - midbrain [nTPM]":"2.8","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"7.4","Tissue RNA - placenta [nTPM]":"1.1","Tissue RNA - pons [nTPM]":"2.2","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"3.9","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"2.6","Tissue RNA - spinal cord [nTPM]":"1.6","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"4.6","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"1.7","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"1.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.8","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.4","Cell RNA - BJ hTERT+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.5","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.4","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.3","Cell RNA - HEL [nTPM]":"2.3","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.7","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"1.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"2.6","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.8","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.1","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"1.2","Cell RNA - U-2 OS [nTPM]":"1.5","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"1.5","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.3","Brain RNA - basal ganglia [nTPM]":"4.0","Brain RNA - cerebellum [nTPM]":"4.6","Brain RNA - cerebral cortex [nTPM]":"5.8","Brain RNA - hippocampal formation [nTPM]":"0.8","Brain RNA - hypothalamus [nTPM]":"3.2","Brain RNA - medulla oblongata [nTPM]":"10.4","Brain RNA - midbrain [nTPM]":"2.8","Brain RNA - pons [nTPM]":"2.2","Brain RNA - spinal cord [nTPM]":"1.6","Brain RNA - thalamus [nTPM]":"4.6","Brain RNA - white matter [nTPM]":"1.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"6.5","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"2.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"82.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"4.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"33.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"32.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"TRPC6","Gene synonym":["FSGS2","TRP6"],"Ensembl":"ENSG00000137672","Gene description":"Transient receptor potential cation channel subfamily C member 6","Uniprot":["Q9Y210"],"Chromosome":"11","Position":"101451564-101872562","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"13.3","placenta":"20.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Club cells":"10.5","Excitatory neurons":"19.3","Inhibitory neurons":"47.2","Microglial cells":"12.2","Smooth muscle cells":"20.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"eosinophil":"2.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"2.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"4.9","ASC diff":"8.8","BJ hTERT+":"4.9","HEL":"4.8","RPTEC TERT1":"21.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045098"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045098":"AB_10959600"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.71e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.3","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"1.2","Tissue RNA - appendix [nTPM]":"0.7","Tissue RNA - basal ganglia [nTPM]":"1.5","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"3.3","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"1.3","Tissue RNA - cervix [nTPM]":"3.4","Tissue RNA - choroid plexus [nTPM]":"5.8","Tissue RNA - colon [nTPM]":"2.8","Tissue RNA - duodenum [nTPM]":"1.2","Tissue RNA - endometrium 1 [nTPM]":"4.8","Tissue RNA - epididymis [nTPM]":"1.6","Tissue RNA - esophagus [nTPM]":"5.7","Tissue RNA - fallopian tube [nTPM]":"5.4","Tissue RNA - gallbladder [nTPM]":"2.3","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"1.5","Tissue RNA - hypothalamus [nTPM]":"1.9","Tissue RNA - kidney [nTPM]":"1.4","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"13.3","Tissue RNA - lymph node [nTPM]":"1.1","Tissue RNA - medulla oblongata [nTPM]":"1.8","Tissue RNA - midbrain [nTPM]":"3.4","Tissue RNA - ovary [nTPM]":"1.2","Tissue RNA - pancreas [nTPM]":"0.7","Tissue RNA - parathyroid gland [nTPM]":"0.9","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"20.8","Tissue RNA - pons [nTPM]":"1.2","Tissue RNA - prostate [nTPM]":"2.2","Tissue RNA - rectum [nTPM]":"1.6","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"0.9","Tissue RNA - seminal vesicle [nTPM]":"5.4","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"1.9","Tissue RNA - small intestine [nTPM]":"1.2","Tissue RNA - smooth muscle [nTPM]":"4.0","Tissue RNA - spinal cord [nTPM]":"1.6","Tissue RNA - spleen [nTPM]":"2.2","Tissue RNA - stomach 1 [nTPM]":"1.6","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"2.0","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"9.4","Tissue RNA - tongue [nTPM]":"1.0","Tissue RNA - tonsil [nTPM]":"0.8","Tissue RNA - urinary bladder [nTPM]":"1.8","Tissue RNA - vagina [nTPM]":"2.0","Tissue RNA - white matter [nTPM]":"1.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"4.9","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"8.8","Cell RNA - ASC TERT1 [nTPM]":"2.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"3.2","Cell RNA - BJ hTERT+ [nTPM]":"4.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"4.8","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"2.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"21.5","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"2.1","Cell RNA - T-47d [nTPM]":"0.5","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"2.3","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"1.2","Brain RNA - basal ganglia [nTPM]":"1.5","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"1.3","Brain RNA - hippocampal formation [nTPM]":"1.5","Brain RNA - hypothalamus [nTPM]":"1.9","Brain RNA - medulla oblongata [nTPM]":"1.8","Brain RNA - midbrain [nTPM]":"3.4","Brain RNA - pons [nTPM]":"1.2","Brain RNA - spinal cord [nTPM]":"1.6","Brain RNA - thalamus [nTPM]":"2.0","Brain RNA - white matter [nTPM]":"1.2","Single Cell Type RNA - Adipocytes [nTPM]":"3.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.6","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"10.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"3.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"47.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"5.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"6.2","Single Cell Type RNA - Macrophages [nTPM]":"1.8","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"5.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"2.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.5"},{"Gene":"TRPM1","Gene synonym":["CSNB1C","LTRPC1","MLSN1"],"Ensembl":"ENSG00000134160","Gene description":"Transient receptor potential cation channel subfamily M member 1","Uniprot":["Q7Z4N2"],"Chromosome":"15","Position":"31001061-31161273","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Sensory transduction","Transport","Vision"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Congenital stationary night blindness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"retina":"9.4","skin 1":"4.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Bipolar cells":"627.4","Melanocytes":"158.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"179","RNA cancer specific FPKM":{"melanoma":"14.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"112","RNA cell line specific nTPM":{"SK-MEL-30":"12.1"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014779","HPA071139"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus","Plasma membrane","Centriolar satellite"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Centriolar satellite"],"Subcellular additional location":["Golgi apparatus","Plasma membrane"],"Antibody RRID":{"HPA014779":"AB_2669090","HPA071139":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"9.4","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"4.1","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"1.4","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"12.1","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"627.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"50.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.0","Single Cell Type RNA - Late spermatids [nTPM]":"6.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"158.3","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"11.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"22.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"10.1","Single Cell Type RNA - Spermatogonia [nTPM]":"4.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"TRPM4","Gene synonym":["FLJ20041"],"Ensembl":"ENSG00000130529","Gene description":"Transient receptor potential cation channel subfamily M member 4","Uniprot":["Q8TD43"],"Chromosome":"19","Position":"49157741-49211836","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Adaptive immunity","Immunity","Ion transport","Transport"],"Molecular function":["Calmodulin-binding","Ion channel"],"Disease involvement":["Disease variant","Palmoplantar keratoderma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"179.2","Hepatocytes":"81.7","Intestinal goblet cells":"114.8","Paneth cells":"77.1","Undifferentiated cells":"88.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"prostate cancer":"85.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"dendritic cells":"3.3","granulocytes":"2.8","monocytes":"4.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"OE19":"32.7","RT4":"60.8","SK-BR-3":"38.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041169"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA041169":"AB_2677343"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.20e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.88e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.53e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.8","Tissue RNA - adrenal gland [nTPM]":"6.1","Tissue RNA - amygdala [nTPM]":"5.8","Tissue RNA - appendix [nTPM]":"6.1","Tissue RNA - basal ganglia [nTPM]":"5.4","Tissue RNA - bone marrow [nTPM]":"4.6","Tissue RNA - breast [nTPM]":"13.5","Tissue RNA - cerebellum [nTPM]":"8.5","Tissue RNA - cerebral cortex [nTPM]":"7.0","Tissue RNA - cervix [nTPM]":"11.5","Tissue RNA - choroid plexus [nTPM]":"4.8","Tissue RNA - colon [nTPM]":"46.1","Tissue RNA - duodenum [nTPM]":"25.3","Tissue RNA - endometrium 1 [nTPM]":"9.9","Tissue RNA - epididymis [nTPM]":"2.5","Tissue RNA - esophagus [nTPM]":"13.1","Tissue RNA - fallopian tube [nTPM]":"9.2","Tissue RNA - gallbladder [nTPM]":"7.4","Tissue RNA - heart muscle [nTPM]":"23.0","Tissue RNA - hippocampal formation [nTPM]":"5.9","Tissue RNA - hypothalamus [nTPM]":"4.5","Tissue RNA - kidney [nTPM]":"22.8","Tissue RNA - liver [nTPM]":"15.4","Tissue RNA - lung [nTPM]":"16.0","Tissue RNA - lymph node [nTPM]":"1.8","Tissue RNA - medulla oblongata [nTPM]":"6.2","Tissue RNA - midbrain [nTPM]":"7.4","Tissue RNA - ovary [nTPM]":"3.3","Tissue RNA - pancreas [nTPM]":"10.1","Tissue RNA - parathyroid gland [nTPM]":"3.7","Tissue RNA - pituitary gland [nTPM]":"5.6","Tissue RNA - placenta [nTPM]":"5.3","Tissue RNA - pons [nTPM]":"6.9","Tissue RNA - prostate [nTPM]":"35.7","Tissue RNA - rectum [nTPM]":"12.9","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"27.3","Tissue RNA - seminal vesicle [nTPM]":"6.2","Tissue RNA - skeletal muscle [nTPM]":"14.0","Tissue RNA - skin 1 [nTPM]":"26.6","Tissue RNA - small intestine [nTPM]":"22.9","Tissue RNA - smooth muscle [nTPM]":"3.4","Tissue RNA - spinal cord [nTPM]":"4.2","Tissue RNA - spleen [nTPM]":"5.5","Tissue RNA - stomach 1 [nTPM]":"20.6","Tissue RNA - testis [nTPM]":"5.4","Tissue RNA - thalamus [nTPM]":"6.6","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"17.3","Tissue RNA - tongue [nTPM]":"5.3","Tissue RNA - tonsil [nTPM]":"1.9","Tissue RNA - urinary bladder [nTPM]":"13.7","Tissue RNA - vagina [nTPM]":"14.4","Tissue RNA - white matter [nTPM]":"5.1","Cell RNA - A-431 [nTPM]":"11.9","Cell RNA - A549 [nTPM]":"9.0","Cell RNA - AF22 [nTPM]":"2.1","Cell RNA - AN3-CA [nTPM]":"9.5","Cell RNA - ASC diff [nTPM]":"7.7","Cell RNA - ASC TERT1 [nTPM]":"6.6","Cell RNA - BEWO [nTPM]":"6.6","Cell RNA - BJ [nTPM]":"10.0","Cell RNA - BJ hTERT+ [nTPM]":"6.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.7","Cell RNA - CACO-2 [nTPM]":"6.1","Cell RNA - CAPAN-2 [nTPM]":"18.7","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"2.7","Cell RNA - fHDF\/TERT166 [nTPM]":"6.8","Cell RNA - GAMG [nTPM]":"3.6","Cell RNA - HaCaT [nTPM]":"15.7","Cell RNA - HAP1 [nTPM]":"1.3","Cell RNA - HBEC3-KT [nTPM]":"3.0","Cell RNA - HBF TERT88 [nTPM]":"1.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"3.4","Cell RNA - HEL [nTPM]":"1.9","Cell RNA - HeLa [nTPM]":"4.0","Cell RNA - Hep G2 [nTPM]":"3.7","Cell RNA - HHSteC [nTPM]":"6.6","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"11.7","Cell RNA - HSkMC [nTPM]":"9.3","Cell RNA - hTCEpi [nTPM]":"13.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.3","Cell RNA - hTERT-HME1 [nTPM]":"2.6","Cell RNA - hTERT-RPE1 [nTPM]":"3.3","Cell RNA - HUVEC TERT2 [nTPM]":"4.6","Cell RNA - JURKAT [nTPM]":"1.0","Cell RNA - K-562 [nTPM]":"4.9","Cell RNA - Karpas-707 [nTPM]":"2.1","Cell RNA - LHCN-M2 [nTPM]":"6.9","Cell RNA - MCF7 [nTPM]":"17.4","Cell RNA - MOLT-4 [nTPM]":"0.8","Cell RNA - NB-4 [nTPM]":"0.9","Cell RNA - NTERA-2 [nTPM]":"1.0","Cell RNA - OE19 [nTPM]":"32.7","Cell RNA - PC-3 [nTPM]":"13.3","Cell RNA - REH [nTPM]":"4.1","Cell RNA - RH-30 [nTPM]":"2.0","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"4.6","Cell RNA - RT4 [nTPM]":"60.8","Cell RNA - SCLC-21H [nTPM]":"0.8","Cell RNA - SH-SY5Y [nTPM]":"2.2","Cell RNA - SiHa [nTPM]":"4.1","Cell RNA - SK-BR-3 [nTPM]":"38.6","Cell RNA - SK-MEL-30 [nTPM]":"2.2","Cell RNA - SuSa [nTPM]":"0.7","Cell RNA - T-47d [nTPM]":"22.6","Cell RNA - THP-1 [nTPM]":"3.7","Cell RNA - TIME [nTPM]":"11.8","Cell RNA - U-138 MG [nTPM]":"14.4","Cell RNA - U-2 OS [nTPM]":"7.8","Cell RNA - U-2197 [nTPM]":"7.9","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"3.9","Cell RNA - U-266\/84 [nTPM]":"4.3","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"7.9","Cell RNA - U-937 [nTPM]":"7.4","Cell RNA - WM-115 [nTPM]":"5.3","Blood RNA - basophil [nTPM]":"2.2","Blood RNA - classical monocyte [nTPM]":"4.3","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"2.5","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"3.3","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"2.8","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"1.0","Blood RNA - plasmacytoid DC [nTPM]":"3.1","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"5.8","Brain RNA - basal ganglia [nTPM]":"5.4","Brain RNA - cerebellum [nTPM]":"8.5","Brain RNA - cerebral cortex [nTPM]":"7.0","Brain RNA - hippocampal formation [nTPM]":"5.9","Brain RNA - hypothalamus [nTPM]":"4.5","Brain RNA - medulla oblongata [nTPM]":"6.2","Brain RNA - midbrain [nTPM]":"7.4","Brain RNA - pons [nTPM]":"6.9","Brain RNA - spinal cord [nTPM]":"4.2","Brain RNA - thalamus [nTPM]":"6.6","Brain RNA - white matter [nTPM]":"5.1","Single Cell Type RNA - Adipocytes [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.6","Single Cell Type RNA - Astrocytes [nTPM]":"9.8","Single Cell Type RNA - B-cells [nTPM]":"3.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"2.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"12.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"179.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"7.9","Single Cell Type RNA - Early spermatids [nTPM]":"2.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.2","Single Cell Type RNA - Endothelial cells [nTPM]":"11.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.7","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.8","Single Cell Type RNA - Fibroblasts [nTPM]":"6.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"71.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"36.2","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"2.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.4","Single Cell Type RNA - Hepatocytes [nTPM]":"81.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"114.8","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"9.8","Single Cell Type RNA - Langerhans cells [nTPM]":"19.0","Single Cell Type RNA - Late spermatids [nTPM]":"3.1","Single Cell Type RNA - Leydig cells [nTPM]":"6.8","Single Cell Type RNA - Macrophages [nTPM]":"8.5","Single Cell Type RNA - Melanocytes [nTPM]":"39.2","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"12.8","Single Cell Type RNA - Muller glia cells [nTPM]":"6.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"32.9","Single Cell Type RNA - Paneth cells [nTPM]":"77.1","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"7.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"35.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"55.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.6","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.5","Single Cell Type RNA - Spermatocytes [nTPM]":"6.1","Single Cell Type RNA - Spermatogonia [nTPM]":"15.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - T-cells [nTPM]":"1.9","Single Cell Type RNA - Theca cells [nTPM]":"4.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"88.9","Single Cell Type RNA - Urothelial cells [nTPM]":"33.1"},{"Gene":"TRPM6","Gene synonym":["CHAK2","FLJ22628","HOMG","HSH"],"Ensembl":"ENSG00000119121","Gene description":"Transient receptor potential cation channel subfamily M member 6","Uniprot":["Q9BX84"],"Chromosome":"9","Position":"74722495-74888094","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Primary hypomagnesemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"6.6","intestine":"16.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"128.9","Glandular and luminal cells":"36.5","Microglial cells":"39.4","Oligodendrocytes":"81.1","Proximal enterocytes":"23.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"1.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"23.1","neutrophil":"7.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"41","RNA blood lineage specific nTPM":{"granulocytes":"23.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"3.8","HeLa":"2.4","Karpas-707":"1.3","RT4":"3.8","U-266\/70":"1.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.6","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"2.1","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"3.5","Tissue RNA - bone marrow [nTPM]":"2.6","Tissue RNA - breast [nTPM]":"0.6","Tissue RNA - cerebellum [nTPM]":"3.0","Tissue RNA - cerebral cortex [nTPM]":"2.4","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"13.2","Tissue RNA - duodenum [nTPM]":"7.0","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"1.6","Tissue RNA - hypothalamus [nTPM]":"2.8","Tissue RNA - kidney [nTPM]":"1.9","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"4.2","Tissue RNA - midbrain [nTPM]":"3.4","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"1.4","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"4.1","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"16.6","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"7.9","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"2.7","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"1.4","Tissue RNA - thalamus [nTPM]":"3.1","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"6.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"3.8","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"1.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"2.4","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"1.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.5","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"3.8","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"1.4","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"23.1","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"2.4","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"7.5","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"2.1","Brain RNA - basal ganglia [nTPM]":"3.5","Brain RNA - cerebellum [nTPM]":"3.0","Brain RNA - cerebral cortex [nTPM]":"2.4","Brain RNA - hippocampal formation [nTPM]":"1.6","Brain RNA - hypothalamus [nTPM]":"2.8","Brain RNA - medulla oblongata [nTPM]":"4.2","Brain RNA - midbrain [nTPM]":"3.4","Brain RNA - pons [nTPM]":"4.1","Brain RNA - spinal cord [nTPM]":"2.7","Brain RNA - thalamus [nTPM]":"3.1","Brain RNA - white matter [nTPM]":"6.6","Single Cell Type RNA - Adipocytes [nTPM]":"3.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.7","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"128.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"4.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.4","Single Cell Type RNA - Endothelial cells [nTPM]":"3.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"36.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"39.4","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"81.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"13.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"1.6","Single Cell Type RNA - Spermatogonia [nTPM]":"2.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"TRPM7","Gene synonym":["CHAK1","LTRPC7","TRP-PLIK"],"Ensembl":"ENSG00000092439","Gene description":"Transient receptor potential cation channel subfamily M member 7","Uniprot":["Q96QT4"],"Chromosome":"15","Position":"50552473-50686797","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Necrosis","Transport"],"Molecular function":["Calcium channel","Ion channel","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Amyotrophic lateral sclerosis","Neurodegeneration","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"108.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"122.2","Oligodendrocytes":"109.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-2197":"122.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035522","HPA052173"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"HPA035522":null,"HPA052173":"AB_2681749"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Tissue RNA - adipose tissue [nTPM]":"11.5","Tissue RNA - adrenal gland [nTPM]":"9.6","Tissue RNA - amygdala [nTPM]":"4.3","Tissue RNA - appendix [nTPM]":"13.3","Tissue RNA - basal ganglia [nTPM]":"6.5","Tissue RNA - bone marrow [nTPM]":"21.4","Tissue RNA - breast [nTPM]":"13.6","Tissue RNA - cerebellum [nTPM]":"15.4","Tissue RNA - cerebral cortex [nTPM]":"6.7","Tissue RNA - cervix [nTPM]":"10.3","Tissue RNA - choroid plexus [nTPM]":"29.3","Tissue RNA - colon [nTPM]":"13.8","Tissue RNA - duodenum [nTPM]":"14.4","Tissue RNA - endometrium 1 [nTPM]":"12.7","Tissue RNA - epididymis [nTPM]":"14.6","Tissue RNA - esophagus [nTPM]":"8.6","Tissue RNA - fallopian tube [nTPM]":"9.4","Tissue RNA - gallbladder [nTPM]":"11.1","Tissue RNA - heart muscle [nTPM]":"15.5","Tissue RNA - hippocampal formation [nTPM]":"4.8","Tissue RNA - hypothalamus [nTPM]":"3.5","Tissue RNA - kidney [nTPM]":"22.9","Tissue RNA - liver [nTPM]":"25.3","Tissue RNA - lung [nTPM]":"11.6","Tissue RNA - lymph node [nTPM]":"16.6","Tissue RNA - medulla oblongata [nTPM]":"4.9","Tissue RNA - midbrain [nTPM]":"3.9","Tissue RNA - ovary [nTPM]":"16.4","Tissue RNA - pancreas [nTPM]":"12.2","Tissue RNA - parathyroid gland [nTPM]":"108.9","Tissue RNA - pituitary gland [nTPM]":"5.3","Tissue RNA - placenta [nTPM]":"13.3","Tissue RNA - pons [nTPM]":"5.9","Tissue RNA - prostate [nTPM]":"10.9","Tissue RNA - rectum [nTPM]":"14.4","Tissue RNA - retina [nTPM]":"10.5","Tissue RNA - salivary gland [nTPM]":"10.9","Tissue RNA - seminal vesicle [nTPM]":"10.6","Tissue RNA - skeletal muscle [nTPM]":"7.8","Tissue RNA - skin 1 [nTPM]":"16.6","Tissue RNA - small intestine [nTPM]":"13.1","Tissue RNA - smooth muscle [nTPM]":"11.4","Tissue RNA - spinal cord [nTPM]":"3.2","Tissue RNA - spleen [nTPM]":"12.2","Tissue RNA - stomach 1 [nTPM]":"13.6","Tissue RNA - testis [nTPM]":"9.9","Tissue RNA - thalamus [nTPM]":"6.4","Tissue RNA - thymus [nTPM]":"15.5","Tissue RNA - thyroid gland [nTPM]":"17.3","Tissue RNA - tongue [nTPM]":"9.1","Tissue RNA - tonsil [nTPM]":"14.4","Tissue RNA - urinary bladder [nTPM]":"11.4","Tissue RNA - vagina [nTPM]":"8.1","Tissue RNA - white matter [nTPM]":"10.4","Cell RNA - A-431 [nTPM]":"21.4","Cell RNA - A549 [nTPM]":"21.0","Cell RNA - AF22 [nTPM]":"17.2","Cell RNA - AN3-CA [nTPM]":"19.1","Cell RNA - ASC diff [nTPM]":"48.5","Cell RNA - ASC TERT1 [nTPM]":"36.2","Cell RNA - BEWO [nTPM]":"20.9","Cell RNA - BJ [nTPM]":"26.4","Cell RNA - BJ hTERT+ [nTPM]":"36.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.6","Cell RNA - CACO-2 [nTPM]":"29.1","Cell RNA - CAPAN-2 [nTPM]":"11.6","Cell RNA - Daudi [nTPM]":"46.4","Cell RNA - EFO-21 [nTPM]":"12.7","Cell RNA - fHDF\/TERT166 [nTPM]":"30.8","Cell RNA - GAMG [nTPM]":"42.5","Cell RNA - HaCaT [nTPM]":"35.1","Cell RNA - HAP1 [nTPM]":"23.3","Cell RNA - HBEC3-KT [nTPM]":"19.5","Cell RNA - HBF TERT88 [nTPM]":"23.4","Cell RNA - HDLM-2 [nTPM]":"26.0","Cell RNA - HEK 293 [nTPM]":"13.7","Cell RNA - HEL [nTPM]":"37.1","Cell RNA - HeLa [nTPM]":"31.5","Cell RNA - Hep G2 [nTPM]":"15.4","Cell RNA - HHSteC [nTPM]":"44.0","Cell RNA - HL-60 [nTPM]":"38.8","Cell RNA - HMC-1 [nTPM]":"27.6","Cell RNA - HSkMC [nTPM]":"33.9","Cell RNA - hTCEpi [nTPM]":"22.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.8","Cell RNA - hTERT-HME1 [nTPM]":"35.0","Cell RNA - hTERT-RPE1 [nTPM]":"24.0","Cell RNA - HUVEC TERT2 [nTPM]":"13.5","Cell RNA - JURKAT [nTPM]":"28.8","Cell RNA - K-562 [nTPM]":"42.6","Cell RNA - Karpas-707 [nTPM]":"34.5","Cell RNA - LHCN-M2 [nTPM]":"30.4","Cell RNA - MCF7 [nTPM]":"33.7","Cell RNA - MOLT-4 [nTPM]":"25.1","Cell RNA - NB-4 [nTPM]":"18.8","Cell RNA - NTERA-2 [nTPM]":"13.0","Cell RNA - OE19 [nTPM]":"29.4","Cell RNA - PC-3 [nTPM]":"12.8","Cell RNA - REH [nTPM]":"27.2","Cell RNA - RH-30 [nTPM]":"23.7","Cell RNA - RPMI-8226 [nTPM]":"22.7","Cell RNA - RPTEC TERT1 [nTPM]":"23.0","Cell RNA - RT4 [nTPM]":"49.9","Cell RNA - SCLC-21H [nTPM]":"14.2","Cell RNA - SH-SY5Y [nTPM]":"18.1","Cell RNA - SiHa [nTPM]":"18.2","Cell RNA - SK-BR-3 [nTPM]":"28.7","Cell RNA - SK-MEL-30 [nTPM]":"35.8","Cell RNA - SuSa [nTPM]":"30.1","Cell RNA - T-47d [nTPM]":"18.0","Cell RNA - THP-1 [nTPM]":"41.6","Cell RNA - TIME [nTPM]":"20.7","Cell RNA - U-138 MG [nTPM]":"26.1","Cell RNA - U-2 OS [nTPM]":"12.4","Cell RNA - U-2197 [nTPM]":"122.4","Cell RNA - U-251 MG [nTPM]":"30.8","Cell RNA - U-266\/70 [nTPM]":"23.3","Cell RNA - U-266\/84 [nTPM]":"54.9","Cell RNA - U-698 [nTPM]":"44.0","Cell RNA - U-87 MG [nTPM]":"28.4","Cell RNA - U-937 [nTPM]":"77.5","Cell RNA - WM-115 [nTPM]":"24.8","Blood RNA - basophil [nTPM]":"1.8","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"1.6","Blood RNA - gdT-cell [nTPM]":"2.5","Blood RNA - intermediate monocyte [nTPM]":"1.3","Blood RNA - MAIT T-cell [nTPM]":"2.9","Blood RNA - memory B-cell [nTPM]":"2.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.8","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"2.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.6","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"1.7","Blood RNA - NK-cell [nTPM]":"2.4","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"1.9","Blood RNA - T-reg [nTPM]":"2.0","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"4.3","Brain RNA - basal ganglia [nTPM]":"6.5","Brain RNA - cerebellum [nTPM]":"15.4","Brain RNA - cerebral cortex [nTPM]":"6.7","Brain RNA - hippocampal formation [nTPM]":"4.8","Brain RNA - hypothalamus [nTPM]":"3.5","Brain RNA - medulla oblongata [nTPM]":"4.9","Brain RNA - midbrain [nTPM]":"3.9","Brain RNA - pons [nTPM]":"5.9","Brain RNA - spinal cord [nTPM]":"3.2","Brain RNA - thalamus [nTPM]":"6.4","Brain RNA - white matter [nTPM]":"10.4","Single Cell Type RNA - Adipocytes [nTPM]":"23.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.3","Single Cell Type RNA - Astrocytes [nTPM]":"73.1","Single Cell Type RNA - B-cells [nTPM]":"36.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"31.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"44.9","Single Cell Type RNA - Bipolar cells [nTPM]":"21.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"8.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.0","Single Cell Type RNA - dendritic cells [nTPM]":"38.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.7","Single Cell Type RNA - Early spermatids [nTPM]":"33.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"21.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"27.1","Single Cell Type RNA - Endothelial cells [nTPM]":"19.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.5","Single Cell Type RNA - Erythroid cells [nTPM]":"29.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"122.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.4","Single Cell Type RNA - Fibroblasts [nTPM]":"26.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"37.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"23.1","Single Cell Type RNA - granulocytes [nTPM]":"17.7","Single Cell Type RNA - Granulosa cells [nTPM]":"26.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"43.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.6","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"92.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.5","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"22.4","Single Cell Type RNA - Langerhans cells [nTPM]":"19.8","Single Cell Type RNA - Late spermatids [nTPM]":"26.0","Single Cell Type RNA - Leydig cells [nTPM]":"26.4","Single Cell Type RNA - Macrophages [nTPM]":"26.5","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"66.5","Single Cell Type RNA - monocytes [nTPM]":"24.2","Single Cell Type RNA - Muller glia cells [nTPM]":"8.5","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"80.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"109.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.5","Single Cell Type RNA - Paneth cells [nTPM]":"13.9","Single Cell Type RNA - Peritubular cells [nTPM]":"20.3","Single Cell Type RNA - Plasma cells [nTPM]":"33.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"24.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"22.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.0","Single Cell Type RNA - Spermatocytes [nTPM]":"23.1","Single Cell Type RNA - Spermatogonia [nTPM]":"23.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.3","Single Cell Type RNA - T-cells [nTPM]":"34.5","Single Cell Type RNA - Theca cells [nTPM]":"22.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.4","Single Cell Type RNA - Urothelial cells [nTPM]":"11.1"},{"Gene":"TRPV4","Gene synonym":["CMT2C","OTRPC4","TRP12","VR-OAC","VRL-2","VROAC"],"Ensembl":"ENSG00000111199","Gene description":"Transient receptor potential cation channel subfamily V member 4","Uniprot":["Q9HBA0"],"Chromosome":"12","Position":"109783087-109833406","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Calmodulin-binding","Ion channel"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Dwarfism","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"50.8","salivary gland":"19.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"17.1","Cholangiocytes":"20.0","Cytotrophoblasts":"20.0","Kupffer cells":"19.6","Respiratory ciliated cells":"28.2","Syncytiotrophoblasts":"21.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"hippocampal formation":"4.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"7.9","BJ hTERT+":"9.5","EFO-21":"7.2","HaCaT":"14.2","HUVEC TERT2":"8.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007150"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA007150":"AB_1080393"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.10e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.12e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.0","Tissue RNA - adrenal gland [nTPM]":"0.8","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.9","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"1.9","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"2.0","Tissue RNA - choroid plexus [nTPM]":"50.8","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"0.6","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"10.3","Tissue RNA - fallopian tube [nTPM]":"4.7","Tissue RNA - gallbladder [nTPM]":"1.4","Tissue RNA - heart muscle [nTPM]":"0.8","Tissue RNA - hippocampal formation [nTPM]":"4.2","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"14.7","Tissue RNA - liver [nTPM]":"8.6","Tissue RNA - lung [nTPM]":"2.2","Tissue RNA - lymph node [nTPM]":"0.8","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"4.4","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"5.2","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"6.8","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"19.2","Tissue RNA - seminal vesicle [nTPM]":"0.8","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"7.5","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.7","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"2.8","Tissue RNA - stomach 1 [nTPM]":"0.7","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"0.8","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.9","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.9","Tissue RNA - urinary bladder [nTPM]":"1.8","Tissue RNA - vagina [nTPM]":"2.2","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"2.4","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"2.0","Cell RNA - ASC TERT1 [nTPM]":"1.2","Cell RNA - BEWO [nTPM]":"7.9","Cell RNA - BJ [nTPM]":"4.2","Cell RNA - BJ hTERT+ [nTPM]":"9.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"6.4","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"7.2","Cell RNA - fHDF\/TERT166 [nTPM]":"5.8","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"14.2","Cell RNA - HAP1 [nTPM]":"1.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.8","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"3.7","Cell RNA - HHSteC [nTPM]":"0.6","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"3.4","Cell RNA - hTCEpi [nTPM]":"2.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.7","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.6","Cell RNA - HUVEC TERT2 [nTPM]":"8.7","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.5","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"5.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.5","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"4.9","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"2.6","Cell RNA - SuSa [nTPM]":"3.5","Cell RNA - T-47d [nTPM]":"1.1","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"4.5","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"2.6","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"5.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"4.2","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.8","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"12.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.3","Single Cell Type RNA - Fibroblasts [nTPM]":"1.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"7.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"19.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"2.6","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"21.1","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"3.3"},{"Gene":"TRPV6","Gene synonym":["CaT1","ECAC2"],"Ensembl":"ENSG00000165125","Gene description":"Transient receptor potential cation channel subfamily V member 6","Uniprot":["Q9H1D0"],"Chromosome":"7","Position":"142871208-142885745","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Calmodulin-binding","Ion channel"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"38.3","prostate":"23.5","salivary gland":"69.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"18.6","Collecting duct cells":"27.6","Cytotrophoblasts":"17.0","Ductal cells":"80.1","Early spermatids":"25.9","Late spermatids":"37.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"prostate cancer":"16.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"9.6","HaCaT":"18.0","RT4":"30.7","SK-BR-3":"23.5","T-47d":"52.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062864"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 1: Pancreatic cells - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA062864":"AB_2684885"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.39e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"4.2","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"1.1","Tissue RNA - cervix [nTPM]":"0.5","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"8.1","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"2.7","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"8.2","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"5.2","Tissue RNA - liver [nTPM]":"0.9","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.6","Tissue RNA - midbrain [nTPM]":"0.6","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"38.3","Tissue RNA - parathyroid gland [nTPM]":"1.5","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"11.9","Tissue RNA - pons [nTPM]":"0.8","Tissue RNA - prostate [nTPM]":"23.5","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"69.3","Tissue RNA - seminal vesicle [nTPM]":"1.6","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"6.4","Tissue RNA - small intestine [nTPM]":"2.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"4.5","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"1.8","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"1.4","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"9.6","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"18.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"30.7","Cell RNA - SCLC-21H [nTPM]":"1.9","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"23.5","Cell RNA - SK-MEL-30 [nTPM]":"0.6","Cell RNA - SuSa [nTPM]":"0.9","Cell RNA - T-47d [nTPM]":"52.8","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"1.1","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"0.6","Brain RNA - midbrain [nTPM]":"0.6","Brain RNA - pons [nTPM]":"0.8","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"1.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"17.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"80.1","Single Cell Type RNA - Early spermatids [nTPM]":"25.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.8","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.6","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"37.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"2.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"3.1"},{"Gene":"TSEN2","Gene synonym":["MGC2776","SEN2","SEN2L"],"Ensembl":"ENSG00000154743","Gene description":"TRNA splicing endonuclease subunit 2","Uniprot":["Q8NCE0"],"Chromosome":"3","Position":"12484421-12541549","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["mRNA processing","tRNA processing"],"Molecular function":["Lyase"],"Disease involvement":["Neurodegeneration","Pontocerebellar hypoplasia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"43.8","Excitatory neurons":"42.8","Inhibitory neurons":"46.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027120","HPA027125","HPA027268"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Centrosome","Cytosol"],"Antibody RRID":{"HPA027120":"AB_10600197","HPA027125":"AB_10601896","HPA027268":"AB_10601347"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.13e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.49e-4"},"Tissue RNA - adipose tissue [nTPM]":"8.9","Tissue RNA - adrenal gland [nTPM]":"9.4","Tissue RNA - amygdala [nTPM]":"3.4","Tissue RNA - appendix [nTPM]":"1.1","Tissue RNA - basal ganglia [nTPM]":"3.9","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"8.9","Tissue RNA - cerebellum [nTPM]":"4.4","Tissue RNA - cerebral cortex [nTPM]":"4.8","Tissue RNA - cervix [nTPM]":"11.5","Tissue RNA - choroid plexus [nTPM]":"3.7","Tissue RNA - colon [nTPM]":"11.5","Tissue RNA - duodenum [nTPM]":"1.4","Tissue RNA - endometrium 1 [nTPM]":"10.9","Tissue RNA - epididymis [nTPM]":"2.6","Tissue RNA - esophagus [nTPM]":"8.6","Tissue RNA - fallopian tube [nTPM]":"12.0","Tissue RNA - gallbladder [nTPM]":"1.8","Tissue RNA - heart muscle [nTPM]":"15.5","Tissue RNA - hippocampal formation [nTPM]":"3.5","Tissue RNA - hypothalamus [nTPM]":"3.7","Tissue RNA - kidney [nTPM]":"10.2","Tissue RNA - liver [nTPM]":"8.5","Tissue RNA - lung [nTPM]":"6.0","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"3.6","Tissue RNA - midbrain [nTPM]":"3.5","Tissue RNA - ovary [nTPM]":"14.2","Tissue RNA - pancreas [nTPM]":"12.1","Tissue RNA - parathyroid gland [nTPM]":"3.2","Tissue RNA - pituitary gland [nTPM]":"10.9","Tissue RNA - placenta [nTPM]":"0.9","Tissue RNA - pons [nTPM]":"3.6","Tissue RNA - prostate [nTPM]":"10.0","Tissue RNA - rectum [nTPM]":"2.3","Tissue RNA - retina [nTPM]":"3.4","Tissue RNA - salivary gland [nTPM]":"6.7","Tissue RNA - seminal vesicle [nTPM]":"3.2","Tissue RNA - skeletal muscle [nTPM]":"15.9","Tissue RNA - skin 1 [nTPM]":"8.3","Tissue RNA - small intestine [nTPM]":"6.9","Tissue RNA - smooth muscle [nTPM]":"3.2","Tissue RNA - spinal cord [nTPM]":"3.3","Tissue RNA - spleen [nTPM]":"6.6","Tissue RNA - stomach 1 [nTPM]":"9.7","Tissue RNA - testis [nTPM]":"6.7","Tissue RNA - thalamus [nTPM]":"3.9","Tissue RNA - thymus [nTPM]":"2.6","Tissue RNA - thyroid gland [nTPM]":"9.0","Tissue RNA - tongue [nTPM]":"3.8","Tissue RNA - tonsil [nTPM]":"2.2","Tissue RNA - urinary bladder [nTPM]":"11.5","Tissue RNA - vagina [nTPM]":"9.7","Tissue RNA - white matter [nTPM]":"3.8","Cell RNA - A-431 [nTPM]":"6.2","Cell RNA - A549 [nTPM]":"11.8","Cell RNA - AF22 [nTPM]":"5.5","Cell RNA - AN3-CA [nTPM]":"7.4","Cell RNA - ASC diff [nTPM]":"6.3","Cell RNA - ASC TERT1 [nTPM]":"7.7","Cell RNA - BEWO [nTPM]":"7.6","Cell RNA - BJ [nTPM]":"5.8","Cell RNA - BJ hTERT+ [nTPM]":"4.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.1","Cell RNA - CACO-2 [nTPM]":"4.2","Cell RNA - CAPAN-2 [nTPM]":"5.2","Cell RNA - Daudi [nTPM]":"5.5","Cell RNA - EFO-21 [nTPM]":"3.3","Cell RNA - fHDF\/TERT166 [nTPM]":"4.0","Cell RNA - GAMG [nTPM]":"5.8","Cell RNA - HaCaT [nTPM]":"5.8","Cell RNA - HAP1 [nTPM]":"7.8","Cell RNA - HBEC3-KT [nTPM]":"9.4","Cell RNA - HBF TERT88 [nTPM]":"5.4","Cell RNA - HDLM-2 [nTPM]":"5.5","Cell RNA - HEK 293 [nTPM]":"9.8","Cell RNA - HEL [nTPM]":"5.1","Cell RNA - HeLa [nTPM]":"9.1","Cell RNA - Hep G2 [nTPM]":"5.7","Cell RNA - HHSteC [nTPM]":"5.4","Cell RNA - HL-60 [nTPM]":"9.3","Cell RNA - HMC-1 [nTPM]":"2.1","Cell RNA - HSkMC [nTPM]":"4.9","Cell RNA - hTCEpi [nTPM]":"11.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.1","Cell RNA - hTERT-HME1 [nTPM]":"9.7","Cell RNA - hTERT-RPE1 [nTPM]":"3.3","Cell RNA - HUVEC TERT2 [nTPM]":"4.7","Cell RNA - JURKAT [nTPM]":"8.8","Cell RNA - K-562 [nTPM]":"10.7","Cell RNA - Karpas-707 [nTPM]":"3.4","Cell RNA - LHCN-M2 [nTPM]":"6.5","Cell RNA - MCF7 [nTPM]":"11.9","Cell RNA - MOLT-4 [nTPM]":"9.6","Cell RNA - NB-4 [nTPM]":"6.1","Cell RNA - NTERA-2 [nTPM]":"6.5","Cell RNA - OE19 [nTPM]":"10.5","Cell RNA - PC-3 [nTPM]":"13.5","Cell RNA - REH [nTPM]":"4.6","Cell RNA - RH-30 [nTPM]":"2.3","Cell RNA - RPMI-8226 [nTPM]":"13.5","Cell RNA - RPTEC TERT1 [nTPM]":"9.9","Cell RNA - RT4 [nTPM]":"4.8","Cell RNA - SCLC-21H [nTPM]":"1.5","Cell RNA - SH-SY5Y [nTPM]":"4.5","Cell RNA - SiHa [nTPM]":"6.7","Cell RNA - SK-BR-3 [nTPM]":"5.0","Cell RNA - SK-MEL-30 [nTPM]":"4.8","Cell RNA - SuSa [nTPM]":"3.1","Cell RNA - T-47d [nTPM]":"10.1","Cell RNA - THP-1 [nTPM]":"5.1","Cell RNA - TIME [nTPM]":"4.5","Cell RNA - U-138 MG [nTPM]":"4.2","Cell RNA - U-2 OS [nTPM]":"3.9","Cell RNA - U-2197 [nTPM]":"4.7","Cell RNA - U-251 MG [nTPM]":"9.7","Cell RNA - U-266\/70 [nTPM]":"3.1","Cell RNA - U-266\/84 [nTPM]":"8.6","Cell RNA - U-698 [nTPM]":"6.2","Cell RNA - U-87 MG [nTPM]":"5.6","Cell RNA - U-937 [nTPM]":"11.8","Cell RNA - WM-115 [nTPM]":"5.4","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"1.9","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"2.7","Blood RNA - intermediate monocyte [nTPM]":"1.6","Blood RNA - MAIT T-cell [nTPM]":"4.4","Blood RNA - memory B-cell [nTPM]":"3.7","Blood RNA - memory CD4 T-cell [nTPM]":"4.6","Blood RNA - memory CD8 T-cell [nTPM]":"3.8","Blood RNA - myeloid DC [nTPM]":"2.3","Blood RNA - naive B-cell [nTPM]":"3.2","Blood RNA - naive CD4 T-cell [nTPM]":"6.2","Blood RNA - naive CD8 T-cell [nTPM]":"5.1","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"2.5","Blood RNA - non-classical monocyte [nTPM]":"1.7","Blood RNA - plasmacytoid DC [nTPM]":"3.4","Blood RNA - T-reg [nTPM]":"1.6","Blood RNA - total PBMC [nTPM]":"2.6","Brain RNA - amygdala [nTPM]":"3.4","Brain RNA - basal ganglia [nTPM]":"3.9","Brain RNA - cerebellum [nTPM]":"4.4","Brain RNA - cerebral cortex [nTPM]":"4.8","Brain RNA - hippocampal formation [nTPM]":"3.5","Brain RNA - hypothalamus [nTPM]":"3.7","Brain RNA - medulla oblongata [nTPM]":"3.6","Brain RNA - midbrain [nTPM]":"3.5","Brain RNA - pons [nTPM]":"3.6","Brain RNA - spinal cord [nTPM]":"3.3","Brain RNA - thalamus [nTPM]":"3.9","Brain RNA - white matter [nTPM]":"3.8","Single Cell Type RNA - Adipocytes [nTPM]":"5.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.3","Single Cell Type RNA - Astrocytes [nTPM]":"26.1","Single Cell Type RNA - B-cells [nTPM]":"8.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Bipolar cells [nTPM]":"28.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"3.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"43.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.8","Single Cell Type RNA - dendritic cells [nTPM]":"2.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.4","Single Cell Type RNA - Endothelial cells [nTPM]":"6.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"8.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"42.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.3","Single Cell Type RNA - Fibroblasts [nTPM]":"5.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.7","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"17.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"5.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.6","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"46.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.2","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"3.5","Single Cell Type RNA - Langerhans cells [nTPM]":"1.7","Single Cell Type RNA - Late spermatids [nTPM]":"2.8","Single Cell Type RNA - Leydig cells [nTPM]":"9.0","Single Cell Type RNA - Macrophages [nTPM]":"3.6","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"2.4","Single Cell Type RNA - Muller glia cells [nTPM]":"8.0","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"31.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.5","Single Cell Type RNA - Paneth cells [nTPM]":"5.0","Single Cell Type RNA - Peritubular cells [nTPM]":"10.1","Single Cell Type RNA - Plasma cells [nTPM]":"3.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"34.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.3","Single Cell Type RNA - Spermatocytes [nTPM]":"14.0","Single Cell Type RNA - Spermatogonia [nTPM]":"23.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - T-cells [nTPM]":"4.6","Single Cell Type RNA - Theca cells [nTPM]":"15.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.4","Single Cell Type RNA - Urothelial cells [nTPM]":"8.0"},{"Gene":"TSEN34","Gene synonym":["LENG5","SEN34","SEN34L"],"Ensembl":"ENSG00000170892","Gene description":"TRNA splicing endonuclease subunit 34","Uniprot":["Q9BSV6"],"Chromosome":"19","Position":"54189938-54194536","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["mRNA processing","tRNA processing"],"Molecular function":["Lyase"],"Disease involvement":["Disease variant","Neurodegeneration","Pontocerebellar hypoplasia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"5.0","eosinophil":"1.9","neutrophil":"4.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"5.0"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041111","HPA048208"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA041111":"AB_10794263","HPA048208":"AB_2680313"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.44e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Tissue RNA - adipose tissue [nTPM]":"28.5","Tissue RNA - adrenal gland [nTPM]":"68.2","Tissue RNA - amygdala [nTPM]":"2.2","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"1.8","Tissue RNA - bone marrow [nTPM]":"1.3","Tissue RNA - breast [nTPM]":"29.5","Tissue RNA - cerebellum [nTPM]":"2.4","Tissue RNA - cerebral cortex [nTPM]":"2.4","Tissue RNA - cervix [nTPM]":"38.8","Tissue RNA - choroid plexus [nTPM]":"1.8","Tissue RNA - colon [nTPM]":"34.7","Tissue RNA - duodenum [nTPM]":"1.1","Tissue RNA - endometrium 1 [nTPM]":"37.1","Tissue RNA - epididymis [nTPM]":"1.9","Tissue RNA - esophagus [nTPM]":"41.0","Tissue RNA - fallopian tube [nTPM]":"37.8","Tissue RNA - gallbladder [nTPM]":"1.5","Tissue RNA - heart muscle [nTPM]":"26.3","Tissue RNA - hippocampal formation [nTPM]":"2.1","Tissue RNA - hypothalamus [nTPM]":"1.7","Tissue RNA - kidney [nTPM]":"39.1","Tissue RNA - liver [nTPM]":"41.3","Tissue RNA - lung [nTPM]":"31.5","Tissue RNA - lymph node [nTPM]":"1.3","Tissue RNA - medulla oblongata [nTPM]":"2.2","Tissue RNA - midbrain [nTPM]":"1.7","Tissue RNA - ovary [nTPM]":"47.9","Tissue RNA - pancreas [nTPM]":"43.0","Tissue RNA - parathyroid gland [nTPM]":"1.8","Tissue RNA - pituitary gland [nTPM]":"36.0","Tissue RNA - placenta [nTPM]":"1.3","Tissue RNA - pons [nTPM]":"2.0","Tissue RNA - prostate [nTPM]":"36.2","Tissue RNA - rectum [nTPM]":"1.3","Tissue RNA - retina [nTPM]":"2.0","Tissue RNA - salivary gland [nTPM]":"34.0","Tissue RNA - seminal vesicle [nTPM]":"1.9","Tissue RNA - skeletal muscle [nTPM]":"26.7","Tissue RNA - skin 1 [nTPM]":"40.5","Tissue RNA - small intestine [nTPM]":"27.7","Tissue RNA - smooth muscle [nTPM]":"1.2","Tissue RNA - spinal cord [nTPM]":"1.3","Tissue RNA - spleen [nTPM]":"44.1","Tissue RNA - stomach 1 [nTPM]":"34.3","Tissue RNA - testis [nTPM]":"45.0","Tissue RNA - thalamus [nTPM]":"1.7","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"30.9","Tissue RNA - tongue [nTPM]":"1.8","Tissue RNA - tonsil [nTPM]":"0.7","Tissue RNA - urinary bladder [nTPM]":"38.9","Tissue RNA - vagina [nTPM]":"34.2","Tissue RNA - white matter [nTPM]":"2.2","Cell RNA - A-431 [nTPM]":"3.3","Cell RNA - A549 [nTPM]":"1.7","Cell RNA - AF22 [nTPM]":"2.5","Cell RNA - AN3-CA [nTPM]":"3.1","Cell RNA - ASC diff [nTPM]":"1.3","Cell RNA - ASC TERT1 [nTPM]":"2.0","Cell RNA - BEWO [nTPM]":"3.9","Cell RNA - BJ [nTPM]":"0.6","Cell RNA - BJ hTERT+ [nTPM]":"1.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.7","Cell RNA - CACO-2 [nTPM]":"2.1","Cell RNA - CAPAN-2 [nTPM]":"1.1","Cell RNA - Daudi [nTPM]":"1.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.9","Cell RNA - GAMG [nTPM]":"2.5","Cell RNA - HaCaT [nTPM]":"2.5","Cell RNA - HAP1 [nTPM]":"2.6","Cell RNA - HBEC3-KT [nTPM]":"2.3","Cell RNA - HBF TERT88 [nTPM]":"1.4","Cell RNA - HDLM-2 [nTPM]":"1.1","Cell RNA - HEK 293 [nTPM]":"6.2","Cell RNA - HEL [nTPM]":"1.0","Cell RNA - HeLa [nTPM]":"1.1","Cell RNA - Hep G2 [nTPM]":"2.0","Cell RNA - HHSteC [nTPM]":"0.5","Cell RNA - HL-60 [nTPM]":"1.1","Cell RNA - HMC-1 [nTPM]":"1.1","Cell RNA - HSkMC [nTPM]":"1.9","Cell RNA - hTCEpi [nTPM]":"1.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.0","Cell RNA - hTERT-HME1 [nTPM]":"1.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.9","Cell RNA - HUVEC TERT2 [nTPM]":"1.3","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"1.7","Cell RNA - Karpas-707 [nTPM]":"0.9","Cell RNA - LHCN-M2 [nTPM]":"2.4","Cell RNA - MCF7 [nTPM]":"1.4","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"1.5","Cell RNA - OE19 [nTPM]":"2.9","Cell RNA - PC-3 [nTPM]":"1.1","Cell RNA - REH [nTPM]":"1.4","Cell RNA - RH-30 [nTPM]":"2.6","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"3.4","Cell RNA - RT4 [nTPM]":"2.4","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"1.7","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"3.5","Cell RNA - SK-MEL-30 [nTPM]":"3.0","Cell RNA - SuSa [nTPM]":"2.5","Cell RNA - T-47d [nTPM]":"2.6","Cell RNA - THP-1 [nTPM]":"3.1","Cell RNA - TIME [nTPM]":"1.1","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"2.8","Cell RNA - U-2197 [nTPM]":"2.7","Cell RNA - U-251 MG [nTPM]":"3.4","Cell RNA - U-266\/70 [nTPM]":"1.4","Cell RNA - U-266\/84 [nTPM]":"1.9","Cell RNA - U-698 [nTPM]":"0.9","Cell RNA - U-87 MG [nTPM]":"2.6","Cell RNA - U-937 [nTPM]":"1.3","Cell RNA - WM-115 [nTPM]":"1.2","Blood RNA - basophil [nTPM]":"5.0","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"1.9","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"4.8","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"2.2","Brain RNA - basal ganglia [nTPM]":"1.8","Brain RNA - cerebellum [nTPM]":"2.4","Brain RNA - cerebral cortex [nTPM]":"2.4","Brain RNA - hippocampal formation [nTPM]":"2.1","Brain RNA - hypothalamus [nTPM]":"1.7","Brain RNA - medulla oblongata [nTPM]":"2.2","Brain RNA - midbrain [nTPM]":"1.7","Brain RNA - pons [nTPM]":"2.0","Brain RNA - spinal cord [nTPM]":"1.3","Brain RNA - thalamus [nTPM]":"1.7","Brain RNA - white matter [nTPM]":"2.2","Single Cell Type RNA - Adipocytes [nTPM]":"33.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.7","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"28.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"73.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"92.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"137.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"67.2","Single Cell Type RNA - Bipolar cells [nTPM]":"35.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"62.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"60.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"52.9","Single Cell Type RNA - Club cells [nTPM]":"60.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"102.5","Single Cell Type RNA - dendritic cells [nTPM]":"45.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"58.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"95.9","Single Cell Type RNA - Ductal cells [nTPM]":"68.7","Single Cell Type RNA - Early spermatids [nTPM]":"24.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"39.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"37.0","Single Cell Type RNA - Endothelial cells [nTPM]":"32.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"76.8","Single Cell Type RNA - Erythroid cells [nTPM]":"13.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"59.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"98.2","Single Cell Type RNA - Fibroblasts [nTPM]":"47.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"35.3","Single Cell Type RNA - granulocytes [nTPM]":"26.6","Single Cell Type RNA - Granulosa cells [nTPM]":"47.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"35.7","Single Cell Type RNA - Hepatocytes [nTPM]":"40.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"57.8","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"103.7","Single Cell Type RNA - Ionocytes [nTPM]":"122.1","Single Cell Type RNA - Kupffer cells [nTPM]":"37.0","Single Cell Type RNA - Langerhans cells [nTPM]":"53.6","Single Cell Type RNA - Late spermatids [nTPM]":"17.2","Single Cell Type RNA - Leydig cells [nTPM]":"67.7","Single Cell Type RNA - Macrophages [nTPM]":"45.0","Single Cell Type RNA - Melanocytes [nTPM]":"46.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"51.8","Single Cell Type RNA - Muller glia cells [nTPM]":"81.9","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"50.4","Single Cell Type RNA - Paneth cells [nTPM]":"55.9","Single Cell Type RNA - Peritubular cells [nTPM]":"66.5","Single Cell Type RNA - Plasma cells [nTPM]":"27.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"79.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"57.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"110.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"70.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"48.9","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"38.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"60.8","Single Cell Type RNA - Spermatocytes [nTPM]":"40.1","Single Cell Type RNA - Spermatogonia [nTPM]":"77.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"56.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"70.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"111.0","Single Cell Type RNA - T-cells [nTPM]":"32.8","Single Cell Type RNA - Theca cells [nTPM]":"100.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"66.5","Single Cell Type RNA - Urothelial cells [nTPM]":"62.3"},{"Gene":"TSPAN12","Gene synonym":["NET-2","TM4SF12"],"Ensembl":"ENSG00000106025","Gene description":"Tetraspanin 12","Uniprot":["O95859"],"Chromosome":"7","Position":"120787320-120858402","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Angiogenesis"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"91.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"118.6","Collecting duct cells":"103.0","Distal tubular cells":"189.8","Glandular and luminal cells":"87.5","Proximal tubular cells":"111.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"44.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEK 293":"53.0","HUVEC TERT2":"58.3","RH-30":"52.2","RPTEC TERT1":"90.5","RT4":"65.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051570","HPA058244"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Microtubules"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA051570":null,"HPA058244":"AB_2683652"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.34e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Tissue RNA - adipose tissue [nTPM]":"11.9","Tissue RNA - adrenal gland [nTPM]":"65.9","Tissue RNA - amygdala [nTPM]":"4.1","Tissue RNA - appendix [nTPM]":"5.3","Tissue RNA - basal ganglia [nTPM]":"4.4","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"8.7","Tissue RNA - cerebellum [nTPM]":"5.2","Tissue RNA - cerebral cortex [nTPM]":"5.2","Tissue RNA - cervix [nTPM]":"21.4","Tissue RNA - choroid plexus [nTPM]":"2.8","Tissue RNA - colon [nTPM]":"24.0","Tissue RNA - duodenum [nTPM]":"39.4","Tissue RNA - endometrium 1 [nTPM]":"10.5","Tissue RNA - epididymis [nTPM]":"14.9","Tissue RNA - esophagus [nTPM]":"5.0","Tissue RNA - fallopian tube [nTPM]":"10.9","Tissue RNA - gallbladder [nTPM]":"20.4","Tissue RNA - heart muscle [nTPM]":"47.7","Tissue RNA - hippocampal formation [nTPM]":"3.3","Tissue RNA - hypothalamus [nTPM]":"4.7","Tissue RNA - kidney [nTPM]":"91.6","Tissue RNA - liver [nTPM]":"35.8","Tissue RNA - lung [nTPM]":"45.8","Tissue RNA - lymph node [nTPM]":"4.5","Tissue RNA - medulla oblongata [nTPM]":"8.0","Tissue RNA - midbrain [nTPM]":"6.2","Tissue RNA - ovary [nTPM]":"1.7","Tissue RNA - pancreas [nTPM]":"17.4","Tissue RNA - parathyroid gland [nTPM]":"10.7","Tissue RNA - pituitary gland [nTPM]":"7.5","Tissue RNA - placenta [nTPM]":"20.3","Tissue RNA - pons [nTPM]":"5.2","Tissue RNA - prostate [nTPM]":"6.8","Tissue RNA - rectum [nTPM]":"20.4","Tissue RNA - retina [nTPM]":"1.8","Tissue RNA - salivary gland [nTPM]":"46.8","Tissue RNA - seminal vesicle [nTPM]":"22.4","Tissue RNA - skeletal muscle [nTPM]":"3.3","Tissue RNA - skin 1 [nTPM]":"1.6","Tissue RNA - small intestine [nTPM]":"42.0","Tissue RNA - smooth muscle [nTPM]":"11.9","Tissue RNA - spinal cord [nTPM]":"4.6","Tissue RNA - spleen [nTPM]":"28.2","Tissue RNA - stomach 1 [nTPM]":"22.1","Tissue RNA - testis [nTPM]":"3.9","Tissue RNA - thalamus [nTPM]":"8.1","Tissue RNA - thymus [nTPM]":"2.7","Tissue RNA - thyroid gland [nTPM]":"23.4","Tissue RNA - tongue [nTPM]":"5.5","Tissue RNA - tonsil [nTPM]":"4.3","Tissue RNA - urinary bladder [nTPM]":"17.5","Tissue RNA - vagina [nTPM]":"4.0","Tissue RNA - white matter [nTPM]":"3.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"1.4","Cell RNA - AF22 [nTPM]":"15.1","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"3.1","Cell RNA - ASC TERT1 [nTPM]":"1.0","Cell RNA - BEWO [nTPM]":"14.7","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.0","Cell RNA - CACO-2 [nTPM]":"2.5","Cell RNA - CAPAN-2 [nTPM]":"4.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"10.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"1.8","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"7.7","Cell RNA - HBEC3-KT [nTPM]":"1.6","Cell RNA - HBF TERT88 [nTPM]":"1.9","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"53.0","Cell RNA - HEL [nTPM]":"2.8","Cell RNA - HeLa [nTPM]":"14.5","Cell RNA - Hep G2 [nTPM]":"2.2","Cell RNA - HHSteC [nTPM]":"8.1","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"2.5","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.4","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"2.1","Cell RNA - HUVEC TERT2 [nTPM]":"58.3","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"1.8","Cell RNA - LHCN-M2 [nTPM]":"6.8","Cell RNA - MCF7 [nTPM]":"2.0","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"24.5","Cell RNA - OE19 [nTPM]":"11.1","Cell RNA - PC-3 [nTPM]":"9.4","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"52.2","Cell RNA - RPMI-8226 [nTPM]":"2.0","Cell RNA - RPTEC TERT1 [nTPM]":"90.5","Cell RNA - RT4 [nTPM]":"65.4","Cell RNA - SCLC-21H [nTPM]":"12.5","Cell RNA - SH-SY5Y [nTPM]":"7.4","Cell RNA - SiHa [nTPM]":"0.7","Cell RNA - SK-BR-3 [nTPM]":"1.3","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"20.0","Cell RNA - T-47d [nTPM]":"8.0","Cell RNA - THP-1 [nTPM]":"1.9","Cell RNA - TIME [nTPM]":"2.5","Cell RNA - U-138 MG [nTPM]":"12.3","Cell RNA - U-2 OS [nTPM]":"3.8","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"6.5","Cell RNA - U-266\/70 [nTPM]":"15.8","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"1.7","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"5.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.1","Brain RNA - basal ganglia [nTPM]":"4.4","Brain RNA - cerebellum [nTPM]":"5.2","Brain RNA - cerebral cortex [nTPM]":"5.2","Brain RNA - hippocampal formation [nTPM]":"3.3","Brain RNA - hypothalamus [nTPM]":"4.7","Brain RNA - medulla oblongata [nTPM]":"8.0","Brain RNA - midbrain [nTPM]":"6.2","Brain RNA - pons [nTPM]":"5.2","Brain RNA - spinal cord [nTPM]":"4.6","Brain RNA - thalamus [nTPM]":"8.1","Brain RNA - white matter [nTPM]":"3.6","Single Cell Type RNA - Adipocytes [nTPM]":"40.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"118.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"45.0","Single Cell Type RNA - Astrocytes [nTPM]":"18.6","Single Cell Type RNA - B-cells [nTPM]":"1.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"62.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"64.3","Single Cell Type RNA - Club cells [nTPM]":"19.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"103.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"40.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"189.8","Single Cell Type RNA - Ductal cells [nTPM]":"6.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"63.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.0","Single Cell Type RNA - Endothelial cells [nTPM]":"38.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"53.5","Single Cell Type RNA - Fibroblasts [nTPM]":"10.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"87.5","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"1.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.2","Single Cell Type RNA - Hepatocytes [nTPM]":"32.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.9","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"3.6","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"4.1","Single Cell Type RNA - Macrophages [nTPM]":"1.5","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.7","Single Cell Type RNA - Paneth cells [nTPM]":"30.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"2.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"68.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"111.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"8.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"24.2","Single Cell Type RNA - T-cells [nTPM]":"1.9","Single Cell Type RNA - Theca cells [nTPM]":"9.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"35.5","Single Cell Type RNA - Urothelial cells [nTPM]":"28.3"},{"Gene":"TSPAN7","Gene synonym":["A15","CD231","DXS1692E","MRX58","MXS1","TALLA-1","TM4SF2"],"Ensembl":"ENSG00000156298","Gene description":"Tetraspanin 7","Uniprot":["P41732"],"Chromosome":"X","Position":"38561542-38688920","Protein class":["CD markers","Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":null,"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"542.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"274.9","Excitatory neurons":"215.6","Hepatic stellate cells":"407.3","Inhibitory neurons":"249.8","Oligodendrocyte precursor cells":"353.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"71.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"109.5","JURKAT":"380.9","MOLT-4":"239.7","SCLC-21H":"129.0","U-266\/70":"163.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003140","CAB062566","CAB068245"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB062566":"AB_2665608","CAB068245":"AB_2665609","HPA003140":"AB_1078454"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.40e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.70e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.48e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-3"},"Tissue RNA - adipose tissue [nTPM]":"56.1","Tissue RNA - adrenal gland [nTPM]":"125.6","Tissue RNA - amygdala [nTPM]":"355.5","Tissue RNA - appendix [nTPM]":"17.2","Tissue RNA - basal ganglia [nTPM]":"433.8","Tissue RNA - bone marrow [nTPM]":"1.3","Tissue RNA - breast [nTPM]":"33.5","Tissue RNA - cerebellum [nTPM]":"369.5","Tissue RNA - cerebral cortex [nTPM]":"542.1","Tissue RNA - cervix [nTPM]":"42.6","Tissue RNA - choroid plexus [nTPM]":"271.3","Tissue RNA - colon [nTPM]":"68.1","Tissue RNA - duodenum [nTPM]":"36.3","Tissue RNA - endometrium 1 [nTPM]":"43.8","Tissue RNA - epididymis [nTPM]":"37.6","Tissue RNA - esophagus [nTPM]":"33.6","Tissue RNA - fallopian tube [nTPM]":"36.5","Tissue RNA - gallbladder [nTPM]":"25.8","Tissue RNA - heart muscle [nTPM]":"70.3","Tissue RNA - hippocampal formation [nTPM]":"413.7","Tissue RNA - hypothalamus [nTPM]":"334.3","Tissue RNA - kidney [nTPM]":"56.2","Tissue RNA - liver [nTPM]":"45.0","Tissue RNA - lung [nTPM]":"67.4","Tissue RNA - lymph node [nTPM]":"41.1","Tissue RNA - medulla oblongata [nTPM]":"290.3","Tissue RNA - midbrain [nTPM]":"298.8","Tissue RNA - ovary [nTPM]":"19.6","Tissue RNA - pancreas [nTPM]":"19.8","Tissue RNA - parathyroid gland [nTPM]":"13.9","Tissue RNA - pituitary gland [nTPM]":"28.0","Tissue RNA - placenta [nTPM]":"25.1","Tissue RNA - pons [nTPM]":"283.6","Tissue RNA - prostate [nTPM]":"18.8","Tissue RNA - rectum [nTPM]":"64.6","Tissue RNA - retina [nTPM]":"286.9","Tissue RNA - salivary gland [nTPM]":"12.5","Tissue RNA - seminal vesicle [nTPM]":"26.8","Tissue RNA - skeletal muscle [nTPM]":"153.9","Tissue RNA - skin 1 [nTPM]":"19.4","Tissue RNA - small intestine [nTPM]":"34.0","Tissue RNA - smooth muscle [nTPM]":"51.1","Tissue RNA - spinal cord [nTPM]":"291.7","Tissue RNA - spleen [nTPM]":"96.3","Tissue RNA - stomach 1 [nTPM]":"14.5","Tissue RNA - testis [nTPM]":"4.8","Tissue RNA - thalamus [nTPM]":"331.7","Tissue RNA - thymus [nTPM]":"15.7","Tissue RNA - thyroid gland [nTPM]":"51.3","Tissue RNA - tongue [nTPM]":"232.3","Tissue RNA - tonsil [nTPM]":"28.9","Tissue RNA - urinary bladder [nTPM]":"29.7","Tissue RNA - vagina [nTPM]":"16.9","Tissue RNA - white matter [nTPM]":"384.6","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"2.9","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.4","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.8","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"3.8","Cell RNA - HBEC3-KT [nTPM]":"1.6","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"109.5","Cell RNA - HEK 293 [nTPM]":"14.9","Cell RNA - HEL [nTPM]":"0.5","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"67.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"1.2","Cell RNA - HSkMC [nTPM]":"1.5","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"380.9","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"1.7","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"239.7","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"11.2","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"14.6","Cell RNA - RH-30 [nTPM]":"4.6","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"11.0","Cell RNA - RT4 [nTPM]":"1.4","Cell RNA - SCLC-21H [nTPM]":"129.0","Cell RNA - SH-SY5Y [nTPM]":"14.4","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"4.3","Cell RNA - SuSa [nTPM]":"6.5","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"3.1","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"1.0","Cell RNA - U-266\/70 [nTPM]":"163.2","Cell RNA - U-266\/84 [nTPM]":"54.8","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"5.4","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"2.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"355.5","Brain RNA - basal ganglia [nTPM]":"433.8","Brain RNA - cerebellum [nTPM]":"369.5","Brain RNA - cerebral cortex [nTPM]":"542.1","Brain RNA - hippocampal formation [nTPM]":"413.7","Brain RNA - hypothalamus [nTPM]":"334.3","Brain RNA - medulla oblongata [nTPM]":"290.3","Brain RNA - midbrain [nTPM]":"298.8","Brain RNA - pons [nTPM]":"283.6","Brain RNA - spinal cord [nTPM]":"291.7","Brain RNA - thalamus [nTPM]":"331.7","Brain RNA - white matter [nTPM]":"384.6","Single Cell Type RNA - Adipocytes [nTPM]":"116.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.8","Single Cell Type RNA - Astrocytes [nTPM]":"274.9","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"92.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"34.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"4.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"43.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"69.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.6","Single Cell Type RNA - Endothelial cells [nTPM]":"153.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.7","Single Cell Type RNA - Erythroid cells [nTPM]":"5.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"215.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"14.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.6","Single Cell Type RNA - granulocytes [nTPM]":"10.1","Single Cell Type RNA - Granulosa cells [nTPM]":"108.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"407.3","Single Cell Type RNA - Hepatocytes [nTPM]":"4.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"45.1","Single Cell Type RNA - Horizontal cells [nTPM]":"97.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"249.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"15.0","Single Cell Type RNA - Langerhans cells [nTPM]":"10.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"1.5","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"46.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"102.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"353.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"50.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.9","Single Cell Type RNA - Paneth cells [nTPM]":"21.9","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"40.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"107.4","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"26.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"3.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"2.6","Single Cell Type RNA - Theca cells [nTPM]":"27.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"35.7","Single Cell Type RNA - Urothelial cells [nTPM]":"0.9"},{"Gene":"TTBK2","Gene synonym":["KIAA0847","SCA11"],"Ensembl":"ENSG00000128881","Gene description":"Tau tubulin kinase 2","Uniprot":["Q6IQ55"],"Chromosome":"15","Position":"42738730-42920809","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"33.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"153.8","Inhibitory neurons":"185.1","Late spermatids":"146.2","Oligodendrocytes":"125.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018113","HPA049866"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Intermediate filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Intermediate filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA018113":"AB_1858421","HPA049866":"AB_2680923"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.3","Tissue RNA - adrenal gland [nTPM]":"4.2","Tissue RNA - amygdala [nTPM]":"7.7","Tissue RNA - appendix [nTPM]":"3.0","Tissue RNA - basal ganglia [nTPM]":"9.9","Tissue RNA - bone marrow [nTPM]":"5.2","Tissue RNA - breast [nTPM]":"4.4","Tissue RNA - cerebellum [nTPM]":"11.3","Tissue RNA - cerebral cortex [nTPM]":"20.0","Tissue RNA - cervix [nTPM]":"6.0","Tissue RNA - choroid plexus [nTPM]":"2.1","Tissue RNA - colon [nTPM]":"6.7","Tissue RNA - duodenum [nTPM]":"1.6","Tissue RNA - endometrium 1 [nTPM]":"5.3","Tissue RNA - epididymis [nTPM]":"3.9","Tissue RNA - esophagus [nTPM]":"2.6","Tissue RNA - fallopian tube [nTPM]":"5.5","Tissue RNA - gallbladder [nTPM]":"3.7","Tissue RNA - heart muscle [nTPM]":"7.2","Tissue RNA - hippocampal formation [nTPM]":"6.9","Tissue RNA - hypothalamus [nTPM]":"13.9","Tissue RNA - kidney [nTPM]":"3.4","Tissue RNA - liver [nTPM]":"3.1","Tissue RNA - lung [nTPM]":"4.8","Tissue RNA - lymph node [nTPM]":"3.4","Tissue RNA - medulla oblongata [nTPM]":"17.4","Tissue RNA - midbrain [nTPM]":"9.1","Tissue RNA - ovary [nTPM]":"6.4","Tissue RNA - pancreas [nTPM]":"2.5","Tissue RNA - parathyroid gland [nTPM]":"4.6","Tissue RNA - pituitary gland [nTPM]":"5.6","Tissue RNA - placenta [nTPM]":"4.0","Tissue RNA - pons [nTPM]":"18.9","Tissue RNA - prostate [nTPM]":"4.7","Tissue RNA - rectum [nTPM]":"3.0","Tissue RNA - retina [nTPM]":"17.7","Tissue RNA - salivary gland [nTPM]":"3.2","Tissue RNA - seminal vesicle [nTPM]":"3.8","Tissue RNA - skeletal muscle [nTPM]":"10.4","Tissue RNA - skin 1 [nTPM]":"3.1","Tissue RNA - small intestine [nTPM]":"3.9","Tissue RNA - smooth muscle [nTPM]":"5.0","Tissue RNA - spinal cord [nTPM]":"6.3","Tissue RNA - spleen [nTPM]":"4.3","Tissue RNA - stomach 1 [nTPM]":"3.4","Tissue RNA - testis [nTPM]":"33.4","Tissue RNA - thalamus [nTPM]":"16.9","Tissue RNA - thymus [nTPM]":"5.2","Tissue RNA - thyroid gland [nTPM]":"3.8","Tissue RNA - tongue [nTPM]":"6.3","Tissue RNA - tonsil [nTPM]":"3.1","Tissue RNA - urinary bladder [nTPM]":"5.3","Tissue RNA - vagina [nTPM]":"4.7","Tissue RNA - white matter [nTPM]":"13.8","Cell RNA - A-431 [nTPM]":"5.7","Cell RNA - A549 [nTPM]":"3.8","Cell RNA - AF22 [nTPM]":"8.4","Cell RNA - AN3-CA [nTPM]":"4.2","Cell RNA - ASC diff [nTPM]":"6.5","Cell RNA - ASC TERT1 [nTPM]":"6.6","Cell RNA - BEWO [nTPM]":"1.8","Cell RNA - BJ [nTPM]":"4.6","Cell RNA - BJ hTERT+ [nTPM]":"7.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.9","Cell RNA - CACO-2 [nTPM]":"4.3","Cell RNA - CAPAN-2 [nTPM]":"1.3","Cell RNA - Daudi [nTPM]":"3.3","Cell RNA - EFO-21 [nTPM]":"6.1","Cell RNA - fHDF\/TERT166 [nTPM]":"4.7","Cell RNA - GAMG [nTPM]":"9.2","Cell RNA - HaCaT [nTPM]":"3.9","Cell RNA - HAP1 [nTPM]":"8.1","Cell RNA - HBEC3-KT [nTPM]":"6.7","Cell RNA - HBF TERT88 [nTPM]":"6.8","Cell RNA - HDLM-2 [nTPM]":"13.0","Cell RNA - HEK 293 [nTPM]":"3.6","Cell RNA - HEL [nTPM]":"4.8","Cell RNA - HeLa [nTPM]":"6.9","Cell RNA - Hep G2 [nTPM]":"1.6","Cell RNA - HHSteC [nTPM]":"5.0","Cell RNA - HL-60 [nTPM]":"6.7","Cell RNA - HMC-1 [nTPM]":"7.8","Cell RNA - HSkMC [nTPM]":"4.7","Cell RNA - hTCEpi [nTPM]":"6.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.9","Cell RNA - hTERT-HME1 [nTPM]":"21.1","Cell RNA - hTERT-RPE1 [nTPM]":"9.9","Cell RNA - HUVEC TERT2 [nTPM]":"5.2","Cell RNA - JURKAT [nTPM]":"5.1","Cell RNA - K-562 [nTPM]":"7.0","Cell RNA - Karpas-707 [nTPM]":"4.9","Cell RNA - LHCN-M2 [nTPM]":"4.5","Cell RNA - MCF7 [nTPM]":"0.9","Cell RNA - MOLT-4 [nTPM]":"4.1","Cell RNA - NB-4 [nTPM]":"4.3","Cell RNA - NTERA-2 [nTPM]":"2.3","Cell RNA - OE19 [nTPM]":"1.7","Cell RNA - PC-3 [nTPM]":"3.8","Cell RNA - REH [nTPM]":"7.2","Cell RNA - RH-30 [nTPM]":"9.1","Cell RNA - RPMI-8226 [nTPM]":"1.7","Cell RNA - RPTEC TERT1 [nTPM]":"5.8","Cell RNA - RT4 [nTPM]":"4.0","Cell RNA - SCLC-21H [nTPM]":"6.6","Cell RNA - SH-SY5Y [nTPM]":"6.5","Cell RNA - SiHa [nTPM]":"12.6","Cell RNA - SK-BR-3 [nTPM]":"0.9","Cell RNA - SK-MEL-30 [nTPM]":"2.5","Cell RNA - SuSa [nTPM]":"5.8","Cell RNA - T-47d [nTPM]":"2.6","Cell RNA - THP-1 [nTPM]":"8.7","Cell RNA - TIME [nTPM]":"5.8","Cell RNA - U-138 MG [nTPM]":"5.1","Cell RNA - U-2 OS [nTPM]":"4.7","Cell RNA - U-2197 [nTPM]":"5.7","Cell RNA - U-251 MG [nTPM]":"6.0","Cell RNA - U-266\/70 [nTPM]":"7.1","Cell RNA - U-266\/84 [nTPM]":"11.3","Cell RNA - U-698 [nTPM]":"5.5","Cell RNA - U-87 MG [nTPM]":"3.9","Cell RNA - U-937 [nTPM]":"5.8","Cell RNA - WM-115 [nTPM]":"3.0","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"7.7","Brain RNA - basal ganglia [nTPM]":"9.9","Brain RNA - cerebellum [nTPM]":"11.3","Brain RNA - cerebral cortex [nTPM]":"20.0","Brain RNA - hippocampal formation [nTPM]":"6.9","Brain RNA - hypothalamus [nTPM]":"13.9","Brain RNA - medulla oblongata [nTPM]":"17.4","Brain RNA - midbrain [nTPM]":"9.1","Brain RNA - pons [nTPM]":"18.9","Brain RNA - spinal cord [nTPM]":"6.3","Brain RNA - thalamus [nTPM]":"16.9","Brain RNA - white matter [nTPM]":"13.8","Single Cell Type RNA - Adipocytes [nTPM]":"16.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.8","Single Cell Type RNA - Astrocytes [nTPM]":"75.7","Single Cell Type RNA - B-cells [nTPM]":"11.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.2","Single Cell Type RNA - Bipolar cells [nTPM]":"36.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"10.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.1","Single Cell Type RNA - dendritic cells [nTPM]":"9.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.7","Single Cell Type RNA - Early spermatids [nTPM]":"80.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"24.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.7","Single Cell Type RNA - Endothelial cells [nTPM]":"17.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.3","Single Cell Type RNA - Erythroid cells [nTPM]":"17.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"153.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.2","Single Cell Type RNA - Fibroblasts [nTPM]":"15.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.6","Single Cell Type RNA - granulocytes [nTPM]":"19.0","Single Cell Type RNA - Granulosa cells [nTPM]":"16.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.5","Single Cell Type RNA - Hepatocytes [nTPM]":"9.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.4","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"185.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.1","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"16.0","Single Cell Type RNA - Langerhans cells [nTPM]":"25.9","Single Cell Type RNA - Late spermatids [nTPM]":"146.2","Single Cell Type RNA - Leydig cells [nTPM]":"16.8","Single Cell Type RNA - Macrophages [nTPM]":"16.4","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"69.3","Single Cell Type RNA - monocytes [nTPM]":"16.9","Single Cell Type RNA - Muller glia cells [nTPM]":"16.5","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"97.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"125.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.5","Single Cell Type RNA - Paneth cells [nTPM]":"2.6","Single Cell Type RNA - Peritubular cells [nTPM]":"20.3","Single Cell Type RNA - Plasma cells [nTPM]":"6.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"40.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"39.4","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"24.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.3","Single Cell Type RNA - Spermatocytes [nTPM]":"34.5","Single Cell Type RNA - Spermatogonia [nTPM]":"10.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.1","Single Cell Type RNA - T-cells [nTPM]":"13.4","Single Cell Type RNA - Theca cells [nTPM]":"11.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.3","Single Cell Type RNA - Urothelial cells [nTPM]":"7.4"},{"Gene":"TTN","Gene synonym":["CMD1G","CMH9","CMPD4","FLJ32040","LGMD2J","MYLK5","TMD"],"Ensembl":"ENSG00000155657","Gene description":"Titin","Uniprot":["Q8WZ42"],"Chromosome":"2","Position":"178525989-178830802","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Calmodulin-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cardiomyopathy","Disease variant","Limb-girdle muscular dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"167.2","skeletal muscle":"920.6","tongue":"369.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"Cardiomyocytes":"24394.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"head and neck cancer":"1.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RH-30":"1.9"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007042","CAB022682","HPA030048"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"16000000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022682":null,"HPA007042":"AB_1080292","HPA030048":"AB_2732451"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.6","Tissue RNA - adrenal gland [nTPM]":"0.4","Tissue RNA - amygdala [nTPM]":"2.7","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"2.4","Tissue RNA - bone marrow [nTPM]":"4.3","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"2.8","Tissue RNA - cerebral cortex [nTPM]":"4.9","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"2.7","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.7","Tissue RNA - heart muscle [nTPM]":"167.2","Tissue RNA - hippocampal formation [nTPM]":"1.9","Tissue RNA - hypothalamus [nTPM]":"3.4","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"1.2","Tissue RNA - lymph node [nTPM]":"1.4","Tissue RNA - medulla oblongata [nTPM]":"11.2","Tissue RNA - midbrain [nTPM]":"4.4","Tissue RNA - ovary [nTPM]":"0.7","Tissue RNA - pancreas [nTPM]":"1.7","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"6.6","Tissue RNA - prostate [nTPM]":"2.7","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"1.9","Tissue RNA - salivary gland [nTPM]":"7.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"920.6","Tissue RNA - skin 1 [nTPM]":"0.8","Tissue RNA - small intestine [nTPM]":"0.6","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"3.2","Tissue RNA - spleen [nTPM]":"0.7","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"1.6","Tissue RNA - thalamus [nTPM]":"4.8","Tissue RNA - thymus [nTPM]":"0.7","Tissue RNA - thyroid gland [nTPM]":"0.6","Tissue RNA - tongue [nTPM]":"369.5","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"5.3","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.7","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"1.4","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.7","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"1.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.7","Cell RNA - HaCaT [nTPM]":"0.7","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"1.0","Cell RNA - HEK 293 [nTPM]":"0.8","Cell RNA - HEL [nTPM]":"1.5","Cell RNA - HeLa [nTPM]":"1.3","Cell RNA - Hep G2 [nTPM]":"0.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.9","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.6","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.9","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.7","Cell RNA - NB-4 [nTPM]":"1.0","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.7","Cell RNA - REH [nTPM]":"0.5","Cell RNA - RH-30 [nTPM]":"1.9","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.7","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.6","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"1.0","Cell RNA - TIME [nTPM]":"0.7","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"1.4","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"1.4","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.5","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"1.8","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"6.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"5.7","Blood RNA - naive CD4 T-cell [nTPM]":"2.0","Blood RNA - naive CD8 T-cell [nTPM]":"2.6","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"3.6","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"6.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"2.7","Brain RNA - basal ganglia [nTPM]":"2.4","Brain RNA - cerebellum [nTPM]":"2.8","Brain RNA - cerebral cortex [nTPM]":"4.9","Brain RNA - hippocampal formation [nTPM]":"1.9","Brain RNA - hypothalamus [nTPM]":"3.4","Brain RNA - medulla oblongata [nTPM]":"11.2","Brain RNA - midbrain [nTPM]":"4.4","Brain RNA - pons [nTPM]":"6.6","Brain RNA - spinal cord [nTPM]":"3.2","Brain RNA - thalamus [nTPM]":"4.8","Brain RNA - white matter [nTPM]":"5.3","Single Cell Type RNA - Adipocytes [nTPM]":"10.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"173.4","Single Cell Type RNA - Astrocytes [nTPM]":"43.8","Single Cell Type RNA - B-cells [nTPM]":"32.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"102.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"24394.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"6.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - dendritic cells [nTPM]":"6.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"14.1","Single Cell Type RNA - Early spermatids [nTPM]":"43.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.8","Single Cell Type RNA - Endothelial cells [nTPM]":"99.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"3.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"28.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"502.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.2","Single Cell Type RNA - granulocytes [nTPM]":"10.1","Single Cell Type RNA - Granulosa cells [nTPM]":"0.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"31.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"6.4","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"26.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"25.3","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"12.0","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"10.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"27.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1466.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"104.7","Single Cell Type RNA - Spermatocytes [nTPM]":"9.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"24.3","Single Cell Type RNA - Theca cells [nTPM]":"2.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"TUSC3","Gene synonym":["MagT2","MGC13453","MRT22","MRT7","N33","OST3A","SLC58A2"],"Ensembl":"ENSG00000104723","Gene description":"Tumor suppressor candidate 3","Uniprot":["Q13454"],"Chromosome":"8","Position":"15417215-15766649","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"472.9","Extravillous trophoblasts":"321.8","Syncytiotrophoblasts":"783.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049851","HPA049974"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049851":"AB_2680913","HPA049974":"AB_2680976"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.86e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Tissue RNA - adipose tissue [nTPM]":"23.3","Tissue RNA - adrenal gland [nTPM]":"68.8","Tissue RNA - amygdala [nTPM]":"18.7","Tissue RNA - appendix [nTPM]":"8.4","Tissue RNA - basal ganglia [nTPM]":"18.4","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"28.3","Tissue RNA - cerebellum [nTPM]":"22.3","Tissue RNA - cerebral cortex [nTPM]":"17.1","Tissue RNA - cervix [nTPM]":"25.0","Tissue RNA - choroid plexus [nTPM]":"46.6","Tissue RNA - colon [nTPM]":"14.5","Tissue RNA - duodenum [nTPM]":"9.3","Tissue RNA - endometrium 1 [nTPM]":"31.9","Tissue RNA - epididymis [nTPM]":"100.8","Tissue RNA - esophagus [nTPM]":"11.8","Tissue RNA - fallopian tube [nTPM]":"57.6","Tissue RNA - gallbladder [nTPM]":"16.7","Tissue RNA - heart muscle [nTPM]":"34.9","Tissue RNA - hippocampal formation [nTPM]":"17.1","Tissue RNA - hypothalamus [nTPM]":"48.2","Tissue RNA - kidney [nTPM]":"25.2","Tissue RNA - liver [nTPM]":"6.9","Tissue RNA - lung [nTPM]":"18.4","Tissue RNA - lymph node [nTPM]":"6.8","Tissue RNA - medulla oblongata [nTPM]":"8.9","Tissue RNA - midbrain [nTPM]":"11.6","Tissue RNA - ovary [nTPM]":"73.6","Tissue RNA - pancreas [nTPM]":"35.0","Tissue RNA - parathyroid gland [nTPM]":"54.0","Tissue RNA - pituitary gland [nTPM]":"69.6","Tissue RNA - placenta [nTPM]":"80.5","Tissue RNA - pons [nTPM]":"8.9","Tissue RNA - prostate [nTPM]":"46.4","Tissue RNA - rectum [nTPM]":"15.5","Tissue RNA - retina [nTPM]":"40.9","Tissue RNA - salivary gland [nTPM]":"12.1","Tissue RNA - seminal vesicle [nTPM]":"29.7","Tissue RNA - skeletal muscle [nTPM]":"4.5","Tissue RNA - skin 1 [nTPM]":"8.2","Tissue RNA - small intestine [nTPM]":"8.2","Tissue RNA - smooth muscle [nTPM]":"32.5","Tissue RNA - spinal cord [nTPM]":"7.7","Tissue RNA - spleen [nTPM]":"5.3","Tissue RNA - stomach 1 [nTPM]":"10.8","Tissue RNA - testis [nTPM]":"23.2","Tissue RNA - thalamus [nTPM]":"21.0","Tissue RNA - thymus [nTPM]":"7.5","Tissue RNA - thyroid gland [nTPM]":"9.5","Tissue RNA - tongue [nTPM]":"5.7","Tissue RNA - tonsil [nTPM]":"5.6","Tissue RNA - urinary bladder [nTPM]":"34.0","Tissue RNA - vagina [nTPM]":"13.0","Tissue RNA - white matter [nTPM]":"8.0","Cell RNA - A-431 [nTPM]":"52.1","Cell RNA - A549 [nTPM]":"38.4","Cell RNA - AF22 [nTPM]":"104.3","Cell RNA - AN3-CA [nTPM]":"96.7","Cell RNA - ASC diff [nTPM]":"125.2","Cell RNA - ASC TERT1 [nTPM]":"126.7","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"74.9","Cell RNA - BJ hTERT+ [nTPM]":"168.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"85.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"139.3","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.7","Cell RNA - EFO-21 [nTPM]":"24.5","Cell RNA - fHDF\/TERT166 [nTPM]":"105.9","Cell RNA - GAMG [nTPM]":"92.4","Cell RNA - HaCaT [nTPM]":"39.3","Cell RNA - HAP1 [nTPM]":"37.5","Cell RNA - HBEC3-KT [nTPM]":"76.1","Cell RNA - HBF TERT88 [nTPM]":"116.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"49.8","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"30.1","Cell RNA - Hep G2 [nTPM]":"6.0","Cell RNA - HHSteC [nTPM]":"51.9","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"5.6","Cell RNA - HSkMC [nTPM]":"111.8","Cell RNA - hTCEpi [nTPM]":"22.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"121.0","Cell RNA - hTERT-HME1 [nTPM]":"43.1","Cell RNA - hTERT-RPE1 [nTPM]":"113.7","Cell RNA - HUVEC TERT2 [nTPM]":"6.9","Cell RNA - JURKAT [nTPM]":"15.9","Cell RNA - K-562 [nTPM]":"70.9","Cell RNA - Karpas-707 [nTPM]":"15.6","Cell RNA - LHCN-M2 [nTPM]":"123.2","Cell RNA - MCF7 [nTPM]":"41.2","Cell RNA - MOLT-4 [nTPM]":"20.6","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"49.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"33.5","Cell RNA - REH [nTPM]":"24.8","Cell RNA - RH-30 [nTPM]":"88.7","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"108.3","Cell RNA - RT4 [nTPM]":"127.1","Cell RNA - SCLC-21H [nTPM]":"40.7","Cell RNA - SH-SY5Y [nTPM]":"74.6","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"40.6","Cell RNA - SK-MEL-30 [nTPM]":"56.5","Cell RNA - SuSa [nTPM]":"76.2","Cell RNA - T-47d [nTPM]":"49.8","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"29.0","Cell RNA - U-138 MG [nTPM]":"71.9","Cell RNA - U-2 OS [nTPM]":"71.3","Cell RNA - U-2197 [nTPM]":"31.3","Cell RNA - U-251 MG [nTPM]":"36.5","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"10.0","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"1.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"102.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"18.7","Brain RNA - basal ganglia [nTPM]":"18.4","Brain RNA - cerebellum [nTPM]":"22.3","Brain RNA - cerebral cortex [nTPM]":"17.1","Brain RNA - hippocampal formation [nTPM]":"17.1","Brain RNA - hypothalamus [nTPM]":"48.2","Brain RNA - medulla oblongata [nTPM]":"8.9","Brain RNA - midbrain [nTPM]":"11.6","Brain RNA - pons [nTPM]":"8.9","Brain RNA - spinal cord [nTPM]":"7.7","Brain RNA - thalamus [nTPM]":"21.0","Brain RNA - white matter [nTPM]":"8.0","Single Cell Type RNA - Adipocytes [nTPM]":"88.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.3","Single Cell Type RNA - Astrocytes [nTPM]":"13.4","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"61.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"123.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"63.7","Single Cell Type RNA - Bipolar cells [nTPM]":"50.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"40.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"52.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"47.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"47.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"79.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"472.9","Single Cell Type RNA - dendritic cells [nTPM]":"0.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"179.0","Single Cell Type RNA - Early spermatids [nTPM]":"11.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"100.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"48.6","Single Cell Type RNA - Endothelial cells [nTPM]":"36.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"95.7","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"141.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"321.8","Single Cell Type RNA - Fibroblasts [nTPM]":"53.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"35.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"39.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"41.8","Single Cell Type RNA - Horizontal cells [nTPM]":"32.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"155.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.3","Single Cell Type RNA - Ionocytes [nTPM]":"95.6","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"6.3","Single Cell Type RNA - Late spermatids [nTPM]":"7.6","Single Cell Type RNA - Leydig cells [nTPM]":"34.8","Single Cell Type RNA - Macrophages [nTPM]":"1.5","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"24.4","Single Cell Type RNA - monocytes [nTPM]":"1.6","Single Cell Type RNA - Muller glia cells [nTPM]":"35.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"61.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"23.8","Single Cell Type RNA - Paneth cells [nTPM]":"4.1","Single Cell Type RNA - Peritubular cells [nTPM]":"23.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"63.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"172.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"28.1","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"49.7","Single Cell Type RNA - Spermatocytes [nTPM]":"60.9","Single Cell Type RNA - Spermatogonia [nTPM]":"47.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"783.8","Single Cell Type RNA - T-cells [nTPM]":"1.6","Single Cell Type RNA - Theca cells [nTPM]":"46.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.8","Single Cell Type RNA - Urothelial cells [nTPM]":"51.4"},{"Gene":"TWNK","Gene synonym":["C10orf2","FLJ21832","IOSCA","PEO","PEO1","TWINKLE","TWINL"],"Ensembl":"ENSG00000107815","Gene description":"Twinkle mtDNA helicase","Uniprot":["Q96RR1"],"Chromosome":"10","Position":"100987367-100994403","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA replication"],"Molecular function":["Helicase","Hydrolase"],"Disease involvement":["Deafness","Disease variant","Neurodegeneration","Neuropathy","Primary mitochondrial disease","Progressive external ophthalmoplegia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"6.8","Breast myoepithelial cells":"6.6","Ductal cells":"5.4","Endometrial stromal cells":"7.2","Granulosa cells":"7.1","Theca cells":"9.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002532"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA002532":"AB_1078311"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.82e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Tissue RNA - adipose tissue [nTPM]":"4.9","Tissue RNA - adrenal gland [nTPM]":"7.0","Tissue RNA - amygdala [nTPM]":"3.7","Tissue RNA - appendix [nTPM]":"5.5","Tissue RNA - basal ganglia [nTPM]":"3.7","Tissue RNA - bone marrow [nTPM]":"3.0","Tissue RNA - breast [nTPM]":"7.5","Tissue RNA - cerebellum [nTPM]":"3.6","Tissue RNA - cerebral cortex [nTPM]":"3.5","Tissue RNA - cervix [nTPM]":"3.8","Tissue RNA - choroid plexus [nTPM]":"3.2","Tissue RNA - colon [nTPM]":"4.4","Tissue RNA - duodenum [nTPM]":"3.3","Tissue RNA - endometrium 1 [nTPM]":"4.6","Tissue RNA - epididymis [nTPM]":"5.3","Tissue RNA - esophagus [nTPM]":"5.5","Tissue RNA - fallopian tube [nTPM]":"6.6","Tissue RNA - gallbladder [nTPM]":"2.6","Tissue RNA - heart muscle [nTPM]":"5.0","Tissue RNA - hippocampal formation [nTPM]":"3.4","Tissue RNA - hypothalamus [nTPM]":"3.6","Tissue RNA - kidney [nTPM]":"5.9","Tissue RNA - liver [nTPM]":"6.0","Tissue RNA - lung [nTPM]":"2.1","Tissue RNA - lymph node [nTPM]":"6.1","Tissue RNA - medulla oblongata [nTPM]":"3.9","Tissue RNA - midbrain [nTPM]":"4.0","Tissue RNA - ovary [nTPM]":"5.1","Tissue RNA - pancreas [nTPM]":"5.2","Tissue RNA - parathyroid gland [nTPM]":"4.8","Tissue RNA - pituitary gland [nTPM]":"2.4","Tissue RNA - placenta [nTPM]":"3.8","Tissue RNA - pons [nTPM]":"3.8","Tissue RNA - prostate [nTPM]":"4.0","Tissue RNA - rectum [nTPM]":"4.8","Tissue RNA - retina [nTPM]":"1.6","Tissue RNA - salivary gland [nTPM]":"4.0","Tissue RNA - seminal vesicle [nTPM]":"3.4","Tissue RNA - skeletal muscle [nTPM]":"11.6","Tissue RNA - skin 1 [nTPM]":"5.5","Tissue RNA - small intestine [nTPM]":"3.8","Tissue RNA - smooth muscle [nTPM]":"4.5","Tissue RNA - spinal cord [nTPM]":"3.7","Tissue RNA - spleen [nTPM]":"4.6","Tissue RNA - stomach 1 [nTPM]":"3.9","Tissue RNA - testis [nTPM]":"8.3","Tissue RNA - thalamus [nTPM]":"4.0","Tissue RNA - thymus [nTPM]":"8.1","Tissue RNA - thyroid gland [nTPM]":"4.1","Tissue RNA - tongue [nTPM]":"12.6","Tissue RNA - tonsil [nTPM]":"8.3","Tissue RNA - urinary bladder [nTPM]":"6.6","Tissue RNA - vagina [nTPM]":"3.5","Tissue RNA - white matter [nTPM]":"3.5","Cell RNA - A-431 [nTPM]":"15.5","Cell RNA - A549 [nTPM]":"32.0","Cell RNA - AF22 [nTPM]":"12.5","Cell RNA - AN3-CA [nTPM]":"39.7","Cell RNA - ASC diff [nTPM]":"11.1","Cell RNA - ASC TERT1 [nTPM]":"7.2","Cell RNA - BEWO [nTPM]":"14.7","Cell RNA - BJ [nTPM]":"11.4","Cell RNA - BJ hTERT+ [nTPM]":"14.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.6","Cell RNA - CACO-2 [nTPM]":"52.6","Cell RNA - CAPAN-2 [nTPM]":"13.1","Cell RNA - Daudi [nTPM]":"55.4","Cell RNA - EFO-21 [nTPM]":"21.1","Cell RNA - fHDF\/TERT166 [nTPM]":"7.0","Cell RNA - GAMG [nTPM]":"10.4","Cell RNA - HaCaT [nTPM]":"25.0","Cell RNA - HAP1 [nTPM]":"52.2","Cell RNA - HBEC3-KT [nTPM]":"27.7","Cell RNA - HBF TERT88 [nTPM]":"21.1","Cell RNA - HDLM-2 [nTPM]":"25.5","Cell RNA - HEK 293 [nTPM]":"31.0","Cell RNA - HEL [nTPM]":"42.1","Cell RNA - HeLa [nTPM]":"17.4","Cell RNA - Hep G2 [nTPM]":"40.2","Cell RNA - HHSteC [nTPM]":"19.1","Cell RNA - HL-60 [nTPM]":"54.8","Cell RNA - HMC-1 [nTPM]":"16.7","Cell RNA - HSkMC [nTPM]":"14.9","Cell RNA - hTCEpi [nTPM]":"30.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.5","Cell RNA - hTERT-HME1 [nTPM]":"77.6","Cell RNA - hTERT-RPE1 [nTPM]":"15.8","Cell RNA - HUVEC TERT2 [nTPM]":"10.6","Cell RNA - JURKAT [nTPM]":"26.3","Cell RNA - K-562 [nTPM]":"45.9","Cell RNA - Karpas-707 [nTPM]":"15.0","Cell RNA - LHCN-M2 [nTPM]":"12.3","Cell RNA - MCF7 [nTPM]":"21.2","Cell RNA - MOLT-4 [nTPM]":"37.0","Cell RNA - NB-4 [nTPM]":"18.8","Cell RNA - NTERA-2 [nTPM]":"35.8","Cell RNA - OE19 [nTPM]":"28.2","Cell RNA - PC-3 [nTPM]":"25.9","Cell RNA - REH [nTPM]":"35.5","Cell RNA - RH-30 [nTPM]":"27.5","Cell RNA - RPMI-8226 [nTPM]":"33.2","Cell RNA - RPTEC TERT1 [nTPM]":"10.7","Cell RNA - RT4 [nTPM]":"15.4","Cell RNA - SCLC-21H [nTPM]":"20.1","Cell RNA - SH-SY5Y [nTPM]":"38.5","Cell RNA - SiHa [nTPM]":"12.0","Cell RNA - SK-BR-3 [nTPM]":"16.0","Cell RNA - SK-MEL-30 [nTPM]":"37.8","Cell RNA - SuSa [nTPM]":"13.8","Cell RNA - T-47d [nTPM]":"20.9","Cell RNA - THP-1 [nTPM]":"16.0","Cell RNA - TIME [nTPM]":"12.4","Cell RNA - U-138 MG [nTPM]":"8.6","Cell RNA - U-2 OS [nTPM]":"17.4","Cell RNA - U-2197 [nTPM]":"10.6","Cell RNA - U-251 MG [nTPM]":"32.5","Cell RNA - U-266\/70 [nTPM]":"28.0","Cell RNA - U-266\/84 [nTPM]":"31.3","Cell RNA - U-698 [nTPM]":"46.0","Cell RNA - U-87 MG [nTPM]":"10.6","Cell RNA - U-937 [nTPM]":"47.8","Cell RNA - WM-115 [nTPM]":"9.8","Blood RNA - basophil [nTPM]":"1.2","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"1.2","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"3.7","Blood RNA - memory B-cell [nTPM]":"2.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.8","Blood RNA - memory CD8 T-cell [nTPM]":"2.7","Blood RNA - myeloid DC [nTPM]":"1.2","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"2.0","Blood RNA - naive CD8 T-cell [nTPM]":"2.2","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"2.5","Blood RNA - non-classical monocyte [nTPM]":"0.8","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"3.7","Brain RNA - basal ganglia [nTPM]":"3.7","Brain RNA - cerebellum [nTPM]":"3.6","Brain RNA - cerebral cortex [nTPM]":"3.5","Brain RNA - hippocampal formation [nTPM]":"3.4","Brain RNA - hypothalamus [nTPM]":"3.6","Brain RNA - medulla oblongata [nTPM]":"3.9","Brain RNA - midbrain [nTPM]":"4.0","Brain RNA - pons [nTPM]":"3.8","Brain RNA - spinal cord [nTPM]":"3.7","Brain RNA - thalamus [nTPM]":"4.0","Brain RNA - white matter [nTPM]":"3.5","Single Cell Type RNA - Adipocytes [nTPM]":"3.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.2","Single Cell Type RNA - dendritic cells [nTPM]":"1.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.2","Single Cell Type RNA - Endothelial cells [nTPM]":"2.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.7","Single Cell Type RNA - Fibroblasts [nTPM]":"1.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.8","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"7.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.6","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"9.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"TXNRD2","Gene synonym":["SELZ","TR","TR3","TRXR2"],"Ensembl":"ENSG00000184470","Gene description":"Thioredoxin reductase 2","Uniprot":["Q9NNW7"],"Chromosome":"22","Position":"19875517-19941820","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-2 OS":"139.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002007","HPA003323"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2800000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Mitochondria","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB002007":null,"HPA003323":"AB_1080396"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.71e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.10e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.5","Tissue RNA - adrenal gland [nTPM]":"44.4","Tissue RNA - amygdala [nTPM]":"11.9","Tissue RNA - appendix [nTPM]":"8.9","Tissue RNA - basal ganglia [nTPM]":"12.0","Tissue RNA - bone marrow [nTPM]":"14.5","Tissue RNA - breast [nTPM]":"12.3","Tissue RNA - cerebellum [nTPM]":"18.1","Tissue RNA - cerebral cortex [nTPM]":"19.3","Tissue RNA - cervix [nTPM]":"11.7","Tissue RNA - choroid plexus [nTPM]":"21.2","Tissue RNA - colon [nTPM]":"14.9","Tissue RNA - duodenum [nTPM]":"10.3","Tissue RNA - endometrium 1 [nTPM]":"10.6","Tissue RNA - epididymis [nTPM]":"6.2","Tissue RNA - esophagus [nTPM]":"10.2","Tissue RNA - fallopian tube [nTPM]":"10.6","Tissue RNA - gallbladder [nTPM]":"6.2","Tissue RNA - heart muscle [nTPM]":"30.0","Tissue RNA - hippocampal formation [nTPM]":"12.9","Tissue RNA - hypothalamus [nTPM]":"11.9","Tissue RNA - kidney [nTPM]":"24.8","Tissue RNA - liver [nTPM]":"65.4","Tissue RNA - lung [nTPM]":"13.6","Tissue RNA - lymph node [nTPM]":"9.1","Tissue RNA - medulla oblongata [nTPM]":"11.8","Tissue RNA - midbrain [nTPM]":"12.1","Tissue RNA - ovary [nTPM]":"16.5","Tissue RNA - pancreas [nTPM]":"15.9","Tissue RNA - parathyroid gland [nTPM]":"13.5","Tissue RNA - pituitary gland [nTPM]":"14.4","Tissue RNA - placenta [nTPM]":"9.8","Tissue RNA - pons [nTPM]":"11.5","Tissue RNA - prostate [nTPM]":"26.8","Tissue RNA - rectum [nTPM]":"4.6","Tissue RNA - retina [nTPM]":"4.4","Tissue RNA - salivary gland [nTPM]":"15.4","Tissue RNA - seminal vesicle [nTPM]":"8.2","Tissue RNA - skeletal muscle [nTPM]":"23.0","Tissue RNA - skin 1 [nTPM]":"10.9","Tissue RNA - small intestine [nTPM]":"12.0","Tissue RNA - smooth muscle [nTPM]":"5.1","Tissue RNA - spinal cord [nTPM]":"11.3","Tissue RNA - spleen [nTPM]":"16.9","Tissue RNA - stomach 1 [nTPM]":"26.4","Tissue RNA - testis [nTPM]":"14.6","Tissue RNA - thalamus [nTPM]":"12.4","Tissue RNA - thymus [nTPM]":"4.9","Tissue RNA - thyroid gland [nTPM]":"15.2","Tissue RNA - tongue [nTPM]":"16.1","Tissue RNA - tonsil [nTPM]":"6.1","Tissue RNA - urinary bladder [nTPM]":"11.8","Tissue RNA - vagina [nTPM]":"10.4","Tissue RNA - white matter [nTPM]":"11.8","Cell RNA - A-431 [nTPM]":"19.4","Cell RNA - A549 [nTPM]":"39.2","Cell RNA - AF22 [nTPM]":"3.5","Cell RNA - AN3-CA [nTPM]":"14.9","Cell RNA - ASC diff [nTPM]":"6.9","Cell RNA - ASC TERT1 [nTPM]":"9.6","Cell RNA - BEWO [nTPM]":"8.8","Cell RNA - BJ [nTPM]":"18.8","Cell RNA - BJ hTERT+ [nTPM]":"21.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"31.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.4","Cell RNA - CACO-2 [nTPM]":"36.7","Cell RNA - CAPAN-2 [nTPM]":"19.4","Cell RNA - Daudi [nTPM]":"10.9","Cell RNA - EFO-21 [nTPM]":"43.2","Cell RNA - fHDF\/TERT166 [nTPM]":"19.0","Cell RNA - GAMG [nTPM]":"32.7","Cell RNA - HaCaT [nTPM]":"33.2","Cell RNA - HAP1 [nTPM]":"17.8","Cell RNA - HBEC3-KT [nTPM]":"25.2","Cell RNA - HBF TERT88 [nTPM]":"12.1","Cell RNA - HDLM-2 [nTPM]":"21.6","Cell RNA - HEK 293 [nTPM]":"46.5","Cell RNA - HEL [nTPM]":"18.8","Cell RNA - HeLa [nTPM]":"34.4","Cell RNA - Hep G2 [nTPM]":"22.4","Cell RNA - HHSteC [nTPM]":"12.9","Cell RNA - HL-60 [nTPM]":"21.1","Cell RNA - HMC-1 [nTPM]":"8.4","Cell RNA - HSkMC [nTPM]":"9.2","Cell RNA - hTCEpi [nTPM]":"18.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.2","Cell RNA - hTERT-HME1 [nTPM]":"13.8","Cell RNA - hTERT-RPE1 [nTPM]":"12.9","Cell RNA - HUVEC TERT2 [nTPM]":"91.3","Cell RNA - JURKAT [nTPM]":"2.2","Cell RNA - K-562 [nTPM]":"106.4","Cell RNA - Karpas-707 [nTPM]":"17.4","Cell RNA - LHCN-M2 [nTPM]":"24.8","Cell RNA - MCF7 [nTPM]":"47.1","Cell RNA - MOLT-4 [nTPM]":"7.2","Cell RNA - NB-4 [nTPM]":"30.1","Cell RNA - NTERA-2 [nTPM]":"17.7","Cell RNA - OE19 [nTPM]":"46.9","Cell RNA - PC-3 [nTPM]":"27.6","Cell RNA - REH [nTPM]":"10.5","Cell RNA - RH-30 [nTPM]":"85.2","Cell RNA - RPMI-8226 [nTPM]":"10.0","Cell RNA - RPTEC TERT1 [nTPM]":"19.3","Cell RNA - RT4 [nTPM]":"21.0","Cell RNA - SCLC-21H [nTPM]":"19.1","Cell RNA - SH-SY5Y [nTPM]":"16.4","Cell RNA - SiHa [nTPM]":"32.0","Cell RNA - SK-BR-3 [nTPM]":"39.9","Cell RNA - SK-MEL-30 [nTPM]":"21.8","Cell RNA - SuSa [nTPM]":"5.8","Cell RNA - T-47d [nTPM]":"33.7","Cell RNA - THP-1 [nTPM]":"27.6","Cell RNA - TIME [nTPM]":"52.2","Cell RNA - U-138 MG [nTPM]":"23.0","Cell RNA - U-2 OS [nTPM]":"139.5","Cell RNA - U-2197 [nTPM]":"19.8","Cell RNA - U-251 MG [nTPM]":"38.4","Cell RNA - U-266\/70 [nTPM]":"17.6","Cell RNA - U-266\/84 [nTPM]":"14.0","Cell RNA - U-698 [nTPM]":"6.9","Cell RNA - U-87 MG [nTPM]":"22.4","Cell RNA - U-937 [nTPM]":"15.5","Cell RNA - WM-115 [nTPM]":"30.3","Blood RNA - basophil [nTPM]":"2.7","Blood RNA - classical monocyte [nTPM]":"10.5","Blood RNA - eosinophil [nTPM]":"5.8","Blood RNA - gdT-cell [nTPM]":"3.5","Blood RNA - intermediate monocyte [nTPM]":"8.2","Blood RNA - MAIT T-cell [nTPM]":"2.6","Blood RNA - memory B-cell [nTPM]":"3.9","Blood RNA - memory CD4 T-cell [nTPM]":"3.0","Blood RNA - memory CD8 T-cell [nTPM]":"3.2","Blood RNA - myeloid DC [nTPM]":"7.8","Blood RNA - naive B-cell [nTPM]":"2.6","Blood RNA - naive CD4 T-cell [nTPM]":"3.9","Blood RNA - naive CD8 T-cell [nTPM]":"3.2","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"3.8","Blood RNA - non-classical monocyte [nTPM]":"7.9","Blood RNA - plasmacytoid DC [nTPM]":"2.9","Blood RNA - T-reg [nTPM]":"2.1","Blood RNA - total PBMC [nTPM]":"4.6","Brain RNA - amygdala [nTPM]":"11.9","Brain RNA - basal ganglia [nTPM]":"12.0","Brain RNA - cerebellum [nTPM]":"18.1","Brain RNA - cerebral cortex [nTPM]":"19.3","Brain RNA - hippocampal formation [nTPM]":"12.9","Brain RNA - hypothalamus [nTPM]":"11.9","Brain RNA - medulla oblongata [nTPM]":"11.8","Brain RNA - midbrain [nTPM]":"12.1","Brain RNA - pons [nTPM]":"11.5","Brain RNA - spinal cord [nTPM]":"11.3","Brain RNA - thalamus [nTPM]":"12.4","Brain RNA - white matter [nTPM]":"11.8","Single Cell Type RNA - Adipocytes [nTPM]":"5.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.6","Single Cell Type RNA - Astrocytes [nTPM]":"11.1","Single Cell Type RNA - B-cells [nTPM]":"10.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"22.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"15.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"60.7","Single Cell Type RNA - dendritic cells [nTPM]":"8.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"58.7","Single Cell Type RNA - Ductal cells [nTPM]":"22.0","Single Cell Type RNA - Early spermatids [nTPM]":"26.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.4","Single Cell Type RNA - Endothelial cells [nTPM]":"14.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"33.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"32.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"24.3","Single Cell Type RNA - Fibroblasts [nTPM]":"12.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"27.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.9","Single Cell Type RNA - Hepatocytes [nTPM]":"49.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.9","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.9","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"22.0","Single Cell Type RNA - Langerhans cells [nTPM]":"7.8","Single Cell Type RNA - Late spermatids [nTPM]":"18.2","Single Cell Type RNA - Leydig cells [nTPM]":"15.5","Single Cell Type RNA - Macrophages [nTPM]":"14.6","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"27.2","Single Cell Type RNA - Muller glia cells [nTPM]":"18.7","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.3","Single Cell Type RNA - Paneth cells [nTPM]":"13.9","Single Cell Type RNA - Peritubular cells [nTPM]":"9.1","Single Cell Type RNA - Plasma cells [nTPM]":"12.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"52.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.3","Single Cell Type RNA - Spermatocytes [nTPM]":"10.9","Single Cell Type RNA - Spermatogonia [nTPM]":"14.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"42.0","Single Cell Type RNA - T-cells [nTPM]":"11.4","Single Cell Type RNA - Theca cells [nTPM]":"36.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.4","Single Cell Type RNA - Urothelial cells [nTPM]":"15.7"},{"Gene":"TYK2","Gene synonym":["JTK1"],"Ensembl":"ENSG00000105397","Gene description":"Tyrosine kinase 2","Uniprot":["P29597"],"Chromosome":"19","Position":"10350529-10380572","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"52.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"NB-4":"206.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005157"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA005157":"AB_1858480"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.62e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.05e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.02e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.43e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.16e-4"},"Tissue RNA - adipose tissue [nTPM]":"53.0","Tissue RNA - adrenal gland [nTPM]":"60.5","Tissue RNA - amygdala [nTPM]":"69.9","Tissue RNA - appendix [nTPM]":"37.0","Tissue RNA - basal ganglia [nTPM]":"71.9","Tissue RNA - bone marrow [nTPM]":"82.6","Tissue RNA - breast [nTPM]":"52.5","Tissue RNA - cerebellum [nTPM]":"70.7","Tissue RNA - cerebral cortex [nTPM]":"82.3","Tissue RNA - cervix [nTPM]":"55.8","Tissue RNA - choroid plexus [nTPM]":"72.2","Tissue RNA - colon [nTPM]":"51.5","Tissue RNA - duodenum [nTPM]":"29.4","Tissue RNA - endometrium 1 [nTPM]":"44.8","Tissue RNA - epididymis [nTPM]":"22.6","Tissue RNA - esophagus [nTPM]":"46.2","Tissue RNA - fallopian tube [nTPM]":"49.0","Tissue RNA - gallbladder [nTPM]":"26.2","Tissue RNA - heart muscle [nTPM]":"65.0","Tissue RNA - hippocampal formation [nTPM]":"69.6","Tissue RNA - hypothalamus [nTPM]":"68.8","Tissue RNA - kidney [nTPM]":"77.3","Tissue RNA - liver [nTPM]":"111.2","Tissue RNA - lung [nTPM]":"72.6","Tissue RNA - lymph node [nTPM]":"51.5","Tissue RNA - medulla oblongata [nTPM]":"75.1","Tissue RNA - midbrain [nTPM]":"71.4","Tissue RNA - ovary [nTPM]":"56.4","Tissue RNA - pancreas [nTPM]":"65.1","Tissue RNA - parathyroid gland [nTPM]":"28.6","Tissue RNA - pituitary gland [nTPM]":"66.2","Tissue RNA - placenta [nTPM]":"20.1","Tissue RNA - pons [nTPM]":"71.5","Tissue RNA - prostate [nTPM]":"64.5","Tissue RNA - rectum [nTPM]":"25.7","Tissue RNA - retina [nTPM]":"25.2","Tissue RNA - salivary gland [nTPM]":"50.8","Tissue RNA - seminal vesicle [nTPM]":"20.6","Tissue RNA - skeletal muscle [nTPM]":"41.3","Tissue RNA - skin 1 [nTPM]":"51.1","Tissue RNA - small intestine [nTPM]":"73.9","Tissue RNA - smooth muscle [nTPM]":"23.5","Tissue RNA - spinal cord [nTPM]":"70.2","Tissue RNA - spleen [nTPM]":"140.8","Tissue RNA - stomach 1 [nTPM]":"54.6","Tissue RNA - testis [nTPM]":"16.6","Tissue RNA - thalamus [nTPM]":"71.8","Tissue RNA - thymus [nTPM]":"54.4","Tissue RNA - thyroid gland [nTPM]":"60.2","Tissue RNA - tongue [nTPM]":"33.7","Tissue RNA - tonsil [nTPM]":"51.8","Tissue RNA - urinary bladder [nTPM]":"49.3","Tissue RNA - vagina [nTPM]":"46.0","Tissue RNA - white matter [nTPM]":"76.4","Cell RNA - A-431 [nTPM]":"29.1","Cell RNA - A549 [nTPM]":"41.1","Cell RNA - AF22 [nTPM]":"24.1","Cell RNA - AN3-CA [nTPM]":"38.0","Cell RNA - ASC diff [nTPM]":"31.9","Cell RNA - ASC TERT1 [nTPM]":"44.2","Cell RNA - BEWO [nTPM]":"23.5","Cell RNA - BJ [nTPM]":"38.9","Cell RNA - BJ hTERT+ [nTPM]":"39.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"48.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"52.2","Cell RNA - CACO-2 [nTPM]":"31.5","Cell RNA - CAPAN-2 [nTPM]":"18.7","Cell RNA - Daudi [nTPM]":"44.5","Cell RNA - EFO-21 [nTPM]":"44.5","Cell RNA - fHDF\/TERT166 [nTPM]":"43.4","Cell RNA - GAMG [nTPM]":"32.8","Cell RNA - HaCaT [nTPM]":"28.4","Cell RNA - HAP1 [nTPM]":"29.4","Cell RNA - HBEC3-KT [nTPM]":"45.5","Cell RNA - HBF TERT88 [nTPM]":"24.2","Cell RNA - HDLM-2 [nTPM]":"78.0","Cell RNA - HEK 293 [nTPM]":"45.5","Cell RNA - HEL [nTPM]":"81.4","Cell RNA - HeLa [nTPM]":"90.5","Cell RNA - Hep G2 [nTPM]":"80.2","Cell RNA - HHSteC [nTPM]":"49.4","Cell RNA - HL-60 [nTPM]":"34.4","Cell RNA - HMC-1 [nTPM]":"89.4","Cell RNA - HSkMC [nTPM]":"43.2","Cell RNA - hTCEpi [nTPM]":"31.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"54.5","Cell RNA - hTERT-HME1 [nTPM]":"32.2","Cell RNA - hTERT-RPE1 [nTPM]":"29.9","Cell RNA - HUVEC TERT2 [nTPM]":"46.5","Cell RNA - JURKAT [nTPM]":"56.6","Cell RNA - K-562 [nTPM]":"35.0","Cell RNA - Karpas-707 [nTPM]":"116.1","Cell RNA - LHCN-M2 [nTPM]":"42.3","Cell RNA - MCF7 [nTPM]":"90.1","Cell RNA - MOLT-4 [nTPM]":"50.7","Cell RNA - NB-4 [nTPM]":"206.9","Cell RNA - NTERA-2 [nTPM]":"7.7","Cell RNA - OE19 [nTPM]":"28.4","Cell RNA - PC-3 [nTPM]":"71.8","Cell RNA - REH [nTPM]":"49.9","Cell RNA - RH-30 [nTPM]":"21.1","Cell RNA - RPMI-8226 [nTPM]":"45.1","Cell RNA - RPTEC TERT1 [nTPM]":"40.0","Cell RNA - RT4 [nTPM]":"90.1","Cell RNA - SCLC-21H [nTPM]":"22.4","Cell RNA - SH-SY5Y [nTPM]":"28.0","Cell RNA - SiHa [nTPM]":"37.6","Cell RNA - SK-BR-3 [nTPM]":"38.6","Cell RNA - SK-MEL-30 [nTPM]":"28.1","Cell RNA - SuSa [nTPM]":"18.4","Cell RNA - T-47d [nTPM]":"21.5","Cell RNA - THP-1 [nTPM]":"57.2","Cell RNA - TIME [nTPM]":"41.1","Cell RNA - U-138 MG [nTPM]":"61.7","Cell RNA - U-2 OS [nTPM]":"22.7","Cell RNA - U-2197 [nTPM]":"74.1","Cell RNA - U-251 MG [nTPM]":"45.9","Cell RNA - U-266\/70 [nTPM]":"97.2","Cell RNA - U-266\/84 [nTPM]":"81.4","Cell RNA - U-698 [nTPM]":"40.2","Cell RNA - U-87 MG [nTPM]":"32.4","Cell RNA - U-937 [nTPM]":"70.8","Cell RNA - WM-115 [nTPM]":"36.6","Blood RNA - basophil [nTPM]":"9.8","Blood RNA - classical monocyte [nTPM]":"20.8","Blood RNA - eosinophil [nTPM]":"27.2","Blood RNA - gdT-cell [nTPM]":"12.8","Blood RNA - intermediate monocyte [nTPM]":"15.2","Blood RNA - MAIT T-cell [nTPM]":"7.9","Blood RNA - memory B-cell [nTPM]":"7.5","Blood RNA - memory CD4 T-cell [nTPM]":"7.6","Blood RNA - memory CD8 T-cell [nTPM]":"11.6","Blood RNA - myeloid DC [nTPM]":"23.5","Blood RNA - naive B-cell [nTPM]":"8.0","Blood RNA - naive CD4 T-cell [nTPM]":"5.0","Blood RNA - naive CD8 T-cell [nTPM]":"7.1","Blood RNA - neutrophil [nTPM]":"33.0","Blood RNA - NK-cell [nTPM]":"8.6","Blood RNA - non-classical monocyte [nTPM]":"15.7","Blood RNA - plasmacytoid DC [nTPM]":"13.0","Blood RNA - T-reg [nTPM]":"10.1","Blood RNA - total PBMC [nTPM]":"13.0","Brain RNA - amygdala [nTPM]":"69.9","Brain RNA - basal ganglia [nTPM]":"71.9","Brain RNA - cerebellum [nTPM]":"70.7","Brain RNA - cerebral cortex [nTPM]":"82.3","Brain RNA - hippocampal formation [nTPM]":"69.6","Brain RNA - hypothalamus [nTPM]":"68.8","Brain RNA - medulla oblongata [nTPM]":"75.1","Brain RNA - midbrain [nTPM]":"71.4","Brain RNA - pons [nTPM]":"71.5","Brain RNA - spinal cord [nTPM]":"70.2","Brain RNA - thalamus [nTPM]":"71.8","Brain RNA - white matter [nTPM]":"76.4","Single Cell Type RNA - Adipocytes [nTPM]":"18.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.9","Single Cell Type RNA - Astrocytes [nTPM]":"13.1","Single Cell Type RNA - B-cells [nTPM]":"17.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Bipolar cells [nTPM]":"9.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"11.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.0","Single Cell Type RNA - dendritic cells [nTPM]":"23.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"52.8","Single Cell Type RNA - Ductal cells [nTPM]":"7.6","Single Cell Type RNA - Early spermatids [nTPM]":"2.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.6","Single Cell Type RNA - Endothelial cells [nTPM]":"12.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"8.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.7","Single Cell Type RNA - Fibroblasts [nTPM]":"11.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"27.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.0","Single Cell Type RNA - granulocytes [nTPM]":"19.6","Single Cell Type RNA - Granulosa cells [nTPM]":"17.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.4","Single Cell Type RNA - Hepatocytes [nTPM]":"27.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.7","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"28.2","Single Cell Type RNA - Langerhans cells [nTPM]":"14.6","Single Cell Type RNA - Late spermatids [nTPM]":"8.8","Single Cell Type RNA - Leydig cells [nTPM]":"7.5","Single Cell Type RNA - Macrophages [nTPM]":"30.8","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"25.3","Single Cell Type RNA - Muller glia cells [nTPM]":"8.7","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.8","Single Cell Type RNA - Paneth cells [nTPM]":"12.9","Single Cell Type RNA - Peritubular cells [nTPM]":"9.8","Single Cell Type RNA - Plasma cells [nTPM]":"19.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"29.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.6","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"4.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.7","Single Cell Type RNA - T-cells [nTPM]":"19.4","Single Cell Type RNA - Theca cells [nTPM]":"13.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.1","Single Cell Type RNA - Urothelial cells [nTPM]":"6.3"},{"Gene":"TYROBP","Gene synonym":["DAP12","KARAP","PLO-SL","PLOSL"],"Ensembl":"ENSG00000011600","Gene description":"Transmembrane immune signaling adaptor TYROBP","Uniprot":["O43914"],"Chromosome":"19","Position":"35904401-35908295","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"596.8","lymphoid tissue":"423.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"3777.1","Kupffer cells":"3698.1","Langerhans cells":"1990.8","Macrophages":"2837.1","monocytes":"3371.2","NK-cells":"1772.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"6415.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"HMC-1":"678.1","THP-1":"390.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009493","HPA041899"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB009493":"AB_638987","HPA041899":"AB_10795266"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.05e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-2"},"Tissue RNA - adipose tissue [nTPM]":"126.3","Tissue RNA - adrenal gland [nTPM]":"76.1","Tissue RNA - amygdala [nTPM]":"55.8","Tissue RNA - appendix [nTPM]":"234.3","Tissue RNA - basal ganglia [nTPM]":"54.3","Tissue RNA - bone marrow [nTPM]":"596.8","Tissue RNA - breast [nTPM]":"59.1","Tissue RNA - cerebellum [nTPM]":"58.6","Tissue RNA - cerebral cortex [nTPM]":"116.8","Tissue RNA - cervix [nTPM]":"44.3","Tissue RNA - choroid plexus [nTPM]":"61.4","Tissue RNA - colon [nTPM]":"62.0","Tissue RNA - duodenum [nTPM]":"70.6","Tissue RNA - endometrium 1 [nTPM]":"25.9","Tissue RNA - epididymis [nTPM]":"15.0","Tissue RNA - esophagus [nTPM]":"28.1","Tissue RNA - fallopian tube [nTPM]":"43.7","Tissue RNA - gallbladder [nTPM]":"105.0","Tissue RNA - heart muscle [nTPM]":"39.7","Tissue RNA - hippocampal formation [nTPM]":"53.0","Tissue RNA - hypothalamus [nTPM]":"66.4","Tissue RNA - kidney [nTPM]":"34.4","Tissue RNA - liver [nTPM]":"85.5","Tissue RNA - lung [nTPM]":"261.5","Tissue RNA - lymph node [nTPM]":"161.0","Tissue RNA - medulla oblongata [nTPM]":"81.7","Tissue RNA - midbrain [nTPM]":"64.0","Tissue RNA - ovary [nTPM]":"18.3","Tissue RNA - pancreas [nTPM]":"24.7","Tissue RNA - parathyroid gland [nTPM]":"22.0","Tissue RNA - pituitary gland [nTPM]":"27.0","Tissue RNA - placenta [nTPM]":"124.7","Tissue RNA - pons [nTPM]":"74.8","Tissue RNA - prostate [nTPM]":"31.7","Tissue RNA - rectum [nTPM]":"49.8","Tissue RNA - retina [nTPM]":"3.9","Tissue RNA - salivary gland [nTPM]":"38.3","Tissue RNA - seminal vesicle [nTPM]":"26.7","Tissue RNA - skeletal muscle [nTPM]":"10.6","Tissue RNA - skin 1 [nTPM]":"21.5","Tissue RNA - small intestine [nTPM]":"78.8","Tissue RNA - smooth muscle [nTPM]":"68.0","Tissue RNA - spinal cord [nTPM]":"74.1","Tissue RNA - spleen [nTPM]":"423.3","Tissue RNA - stomach 1 [nTPM]":"43.1","Tissue RNA - testis [nTPM]":"15.0","Tissue RNA - thalamus [nTPM]":"74.0","Tissue RNA - thymus [nTPM]":"52.5","Tissue RNA - thyroid gland [nTPM]":"21.9","Tissue RNA - tongue [nTPM]":"31.6","Tissue RNA - tonsil [nTPM]":"36.6","Tissue RNA - urinary bladder [nTPM]":"131.7","Tissue RNA - vagina [nTPM]":"21.5","Tissue RNA - white matter [nTPM]":"114.4","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"56.7","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.5","Cell RNA - HL-60 [nTPM]":"33.2","Cell RNA - HMC-1 [nTPM]":"678.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"1.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"49.1","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.5","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.9","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"390.6","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.8","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"1.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"10.8","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"974.2","Blood RNA - classical monocyte [nTPM]":"4983.5","Blood RNA - eosinophil [nTPM]":"2573.9","Blood RNA - gdT-cell [nTPM]":"468.0","Blood RNA - intermediate monocyte [nTPM]":"3367.8","Blood RNA - MAIT T-cell [nTPM]":"246.5","Blood RNA - memory B-cell [nTPM]":"22.4","Blood RNA - memory CD4 T-cell [nTPM]":"9.5","Blood RNA - memory CD8 T-cell [nTPM]":"64.2","Blood RNA - myeloid DC [nTPM]":"1912.0","Blood RNA - naive B-cell [nTPM]":"8.4","Blood RNA - naive CD4 T-cell [nTPM]":"11.7","Blood RNA - naive CD8 T-cell [nTPM]":"51.2","Blood RNA - neutrophil [nTPM]":"6415.4","Blood RNA - NK-cell [nTPM]":"1664.1","Blood RNA - non-classical monocyte [nTPM]":"3413.8","Blood RNA - plasmacytoid DC [nTPM]":"1653.1","Blood RNA - T-reg [nTPM]":"9.5","Blood RNA - total PBMC [nTPM]":"5260.2","Brain RNA - amygdala [nTPM]":"55.8","Brain RNA - basal ganglia [nTPM]":"54.3","Brain RNA - cerebellum [nTPM]":"58.6","Brain RNA - cerebral cortex [nTPM]":"116.8","Brain RNA - hippocampal formation [nTPM]":"53.0","Brain RNA - hypothalamus [nTPM]":"66.4","Brain RNA - medulla oblongata [nTPM]":"81.7","Brain RNA - midbrain [nTPM]":"64.0","Brain RNA - pons [nTPM]":"74.8","Brain RNA - spinal cord [nTPM]":"74.1","Brain RNA - thalamus [nTPM]":"74.0","Brain RNA - white matter [nTPM]":"114.4","Single Cell Type RNA - Adipocytes [nTPM]":"24.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"57.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"168.4","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"50.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"55.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"43.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"34.3","Single Cell Type RNA - Club cells [nTPM]":"43.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.8","Single Cell Type RNA - dendritic cells [nTPM]":"987.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.1","Single Cell Type RNA - Early spermatids [nTPM]":"3.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.4","Single Cell Type RNA - Endothelial cells [nTPM]":"47.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"87.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"28.0","Single Cell Type RNA - Fibroblasts [nTPM]":"24.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.5","Single Cell Type RNA - granulocytes [nTPM]":"753.7","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"73.2","Single Cell Type RNA - Hepatocytes [nTPM]":"25.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"3777.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3698.1","Single Cell Type RNA - Langerhans cells [nTPM]":"1990.8","Single Cell Type RNA - Late spermatids [nTPM]":"11.6","Single Cell Type RNA - Leydig cells [nTPM]":"9.3","Single Cell Type RNA - Macrophages [nTPM]":"2837.1","Single Cell Type RNA - Melanocytes [nTPM]":"56.9","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"3371.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.6","Single Cell Type RNA - NK-cells [nTPM]":"1772.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.3","Single Cell Type RNA - Paneth cells [nTPM]":"2.3","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"19.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.8","Single Cell Type RNA - Sertoli cells [nTPM]":"78.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.9","Single Cell Type RNA - Spermatogonia [nTPM]":"3.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"44.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"38.9","Single Cell Type RNA - T-cells [nTPM]":"236.5","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.5","Single Cell Type RNA - Urothelial cells [nTPM]":"1.8"},{"Gene":"UBA1","Gene synonym":["A1S9T","CFAP124","GXP1","POC20","UBE1","UBE1X"],"Ensembl":"ENSG00000130985","Gene description":"Ubiquitin like modifier activating enzyme 1","Uniprot":["P22314"],"Chromosome":"X","Position":"47190861-47215128","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Ligase"],"Disease involvement":["Cancer-related genes","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000289","HPA001506","CAB019435","CAB073410"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"14000000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB019435":"AB_2211440","CAB073410":null,"HPA000289":"AB_1080443","HPA001506":"AB_2756305"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.10e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.50e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.78e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Tissue RNA - adipose tissue [nTPM]":"98.4","Tissue RNA - adrenal gland [nTPM]":"157.9","Tissue RNA - amygdala [nTPM]":"102.9","Tissue RNA - appendix [nTPM]":"98.3","Tissue RNA - basal ganglia [nTPM]":"113.2","Tissue RNA - bone marrow [nTPM]":"94.3","Tissue RNA - breast [nTPM]":"98.6","Tissue RNA - cerebellum [nTPM]":"103.4","Tissue RNA - cerebral cortex [nTPM]":"115.5","Tissue RNA - cervix [nTPM]":"127.9","Tissue RNA - choroid plexus [nTPM]":"133.9","Tissue RNA - colon [nTPM]":"101.1","Tissue RNA - duodenum [nTPM]":"71.3","Tissue RNA - endometrium 1 [nTPM]":"127.1","Tissue RNA - epididymis [nTPM]":"64.3","Tissue RNA - esophagus [nTPM]":"155.3","Tissue RNA - fallopian tube [nTPM]":"119.3","Tissue RNA - gallbladder [nTPM]":"64.9","Tissue RNA - heart muscle [nTPM]":"117.4","Tissue RNA - hippocampal formation [nTPM]":"106.2","Tissue RNA - hypothalamus [nTPM]":"102.0","Tissue RNA - kidney [nTPM]":"131.2","Tissue RNA - liver [nTPM]":"114.7","Tissue RNA - lung [nTPM]":"109.5","Tissue RNA - lymph node [nTPM]":"105.0","Tissue RNA - medulla oblongata [nTPM]":"106.9","Tissue RNA - midbrain [nTPM]":"104.2","Tissue RNA - ovary [nTPM]":"136.5","Tissue RNA - pancreas [nTPM]":"89.0","Tissue RNA - parathyroid gland [nTPM]":"107.5","Tissue RNA - pituitary gland [nTPM]":"135.2","Tissue RNA - placenta [nTPM]":"67.4","Tissue RNA - pons [nTPM]":"109.3","Tissue RNA - prostate [nTPM]":"103.2","Tissue RNA - rectum [nTPM]":"68.5","Tissue RNA - retina [nTPM]":"95.6","Tissue RNA - salivary gland [nTPM]":"119.5","Tissue RNA - seminal vesicle [nTPM]":"78.9","Tissue RNA - skeletal muscle [nTPM]":"201.1","Tissue RNA - skin 1 [nTPM]":"119.5","Tissue RNA - small intestine [nTPM]":"100.4","Tissue RNA - smooth muscle [nTPM]":"117.4","Tissue RNA - spinal cord [nTPM]":"94.4","Tissue RNA - spleen [nTPM]":"131.9","Tissue RNA - stomach 1 [nTPM]":"98.6","Tissue RNA - testis [nTPM]":"98.7","Tissue RNA - thalamus [nTPM]":"110.0","Tissue RNA - thymus [nTPM]":"119.7","Tissue RNA - thyroid gland [nTPM]":"160.1","Tissue RNA - tongue [nTPM]":"114.1","Tissue RNA - tonsil [nTPM]":"110.8","Tissue RNA - urinary bladder [nTPM]":"101.1","Tissue RNA - vagina [nTPM]":"124.8","Tissue RNA - white matter [nTPM]":"121.3","Cell RNA - A-431 [nTPM]":"269.1","Cell RNA - A549 [nTPM]":"273.2","Cell RNA - AF22 [nTPM]":"307.7","Cell RNA - AN3-CA [nTPM]":"471.9","Cell RNA - ASC diff [nTPM]":"207.4","Cell RNA - ASC TERT1 [nTPM]":"186.8","Cell RNA - BEWO [nTPM]":"135.0","Cell RNA - BJ [nTPM]":"175.1","Cell RNA - BJ hTERT+ [nTPM]":"187.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"248.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"200.5","Cell RNA - CACO-2 [nTPM]":"219.3","Cell RNA - CAPAN-2 [nTPM]":"201.3","Cell RNA - Daudi [nTPM]":"201.6","Cell RNA - EFO-21 [nTPM]":"111.8","Cell RNA - fHDF\/TERT166 [nTPM]":"357.0","Cell RNA - GAMG [nTPM]":"361.5","Cell RNA - HaCaT [nTPM]":"254.9","Cell RNA - HAP1 [nTPM]":"392.9","Cell RNA - HBEC3-KT [nTPM]":"375.7","Cell RNA - HBF TERT88 [nTPM]":"180.9","Cell RNA - HDLM-2 [nTPM]":"163.4","Cell RNA - HEK 293 [nTPM]":"391.7","Cell RNA - HEL [nTPM]":"126.1","Cell RNA - HeLa [nTPM]":"295.2","Cell RNA - Hep G2 [nTPM]":"180.0","Cell RNA - HHSteC [nTPM]":"145.1","Cell RNA - HL-60 [nTPM]":"215.2","Cell RNA - HMC-1 [nTPM]":"258.8","Cell RNA - HSkMC [nTPM]":"177.4","Cell RNA - hTCEpi [nTPM]":"193.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"362.7","Cell RNA - hTERT-HME1 [nTPM]":"279.4","Cell RNA - hTERT-RPE1 [nTPM]":"176.7","Cell RNA - HUVEC TERT2 [nTPM]":"330.2","Cell RNA - JURKAT [nTPM]":"236.1","Cell RNA - K-562 [nTPM]":"138.9","Cell RNA - Karpas-707 [nTPM]":"173.7","Cell RNA - LHCN-M2 [nTPM]":"250.4","Cell RNA - MCF7 [nTPM]":"343.4","Cell RNA - MOLT-4 [nTPM]":"203.3","Cell RNA - NB-4 [nTPM]":"188.5","Cell RNA - NTERA-2 [nTPM]":"329.6","Cell RNA - OE19 [nTPM]":"163.2","Cell RNA - PC-3 [nTPM]":"417.1","Cell RNA - REH [nTPM]":"233.1","Cell RNA - RH-30 [nTPM]":"215.3","Cell RNA - RPMI-8226 [nTPM]":"343.7","Cell RNA - RPTEC TERT1 [nTPM]":"198.7","Cell RNA - RT4 [nTPM]":"287.0","Cell RNA - SCLC-21H [nTPM]":"197.4","Cell RNA - SH-SY5Y [nTPM]":"148.1","Cell RNA - SiHa [nTPM]":"520.8","Cell RNA - SK-BR-3 [nTPM]":"250.9","Cell RNA - SK-MEL-30 [nTPM]":"116.9","Cell RNA - SuSa [nTPM]":"329.9","Cell RNA - T-47d [nTPM]":"349.5","Cell RNA - THP-1 [nTPM]":"130.3","Cell RNA - TIME [nTPM]":"241.6","Cell RNA - U-138 MG [nTPM]":"183.1","Cell RNA - U-2 OS [nTPM]":"210.7","Cell RNA - U-2197 [nTPM]":"266.4","Cell RNA - U-251 MG [nTPM]":"166.1","Cell RNA - U-266\/70 [nTPM]":"117.6","Cell RNA - U-266\/84 [nTPM]":"132.8","Cell RNA - U-698 [nTPM]":"286.3","Cell RNA - U-87 MG [nTPM]":"189.4","Cell RNA - U-937 [nTPM]":"150.8","Cell RNA - WM-115 [nTPM]":"224.9","Blood RNA - basophil [nTPM]":"31.0","Blood RNA - classical monocyte [nTPM]":"39.7","Blood RNA - eosinophil [nTPM]":"40.7","Blood RNA - gdT-cell [nTPM]":"39.4","Blood RNA - intermediate monocyte [nTPM]":"51.1","Blood RNA - MAIT T-cell [nTPM]":"34.0","Blood RNA - memory B-cell [nTPM]":"39.8","Blood RNA - memory CD4 T-cell [nTPM]":"31.8","Blood RNA - memory CD8 T-cell [nTPM]":"35.0","Blood RNA - myeloid DC [nTPM]":"43.2","Blood RNA - naive B-cell [nTPM]":"29.9","Blood RNA - naive CD4 T-cell [nTPM]":"24.7","Blood RNA - naive CD8 T-cell [nTPM]":"31.1","Blood RNA - neutrophil [nTPM]":"44.8","Blood RNA - NK-cell [nTPM]":"38.1","Blood RNA - non-classical monocyte [nTPM]":"49.7","Blood RNA - plasmacytoid DC [nTPM]":"29.3","Blood RNA - T-reg [nTPM]":"40.3","Blood RNA - total PBMC [nTPM]":"39.9","Brain RNA - amygdala [nTPM]":"102.9","Brain RNA - basal ganglia [nTPM]":"113.2","Brain RNA - cerebellum [nTPM]":"103.4","Brain RNA - cerebral cortex [nTPM]":"115.5","Brain RNA - hippocampal formation [nTPM]":"106.2","Brain RNA - hypothalamus [nTPM]":"102.0","Brain RNA - medulla oblongata [nTPM]":"106.9","Brain RNA - midbrain [nTPM]":"104.2","Brain RNA - pons [nTPM]":"109.3","Brain RNA - spinal cord [nTPM]":"94.4","Brain RNA - thalamus [nTPM]":"110.0","Brain RNA - white matter [nTPM]":"121.3","Single Cell Type RNA - Adipocytes [nTPM]":"37.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"34.7","Single Cell Type RNA - Astrocytes [nTPM]":"45.1","Single Cell Type RNA - B-cells [nTPM]":"37.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"33.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"38.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"55.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.2","Single Cell Type RNA - Bipolar cells [nTPM]":"24.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"48.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"39.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"51.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"51.5","Single Cell Type RNA - Club cells [nTPM]":"50.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"82.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"46.3","Single Cell Type RNA - dendritic cells [nTPM]":"34.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"133.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"77.5","Single Cell Type RNA - Early spermatids [nTPM]":"29.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"84.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"56.3","Single Cell Type RNA - Endothelial cells [nTPM]":"40.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"57.5","Single Cell Type RNA - Erythroid cells [nTPM]":"33.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"27.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"90.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"68.7","Single Cell Type RNA - Fibroblasts [nTPM]":"45.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"74.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"97.5","Single Cell Type RNA - granulocytes [nTPM]":"18.3","Single Cell Type RNA - Granulosa cells [nTPM]":"60.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"43.5","Single Cell Type RNA - Hepatocytes [nTPM]":"51.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"60.0","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"35.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"78.6","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"49.0","Single Cell Type RNA - Langerhans cells [nTPM]":"37.8","Single Cell Type RNA - Late spermatids [nTPM]":"61.6","Single Cell Type RNA - Leydig cells [nTPM]":"42.3","Single Cell Type RNA - Macrophages [nTPM]":"51.4","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"31.9","Single Cell Type RNA - monocytes [nTPM]":"57.7","Single Cell Type RNA - Muller glia cells [nTPM]":"20.7","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"32.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"46.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"147.9","Single Cell Type RNA - Paneth cells [nTPM]":"74.7","Single Cell Type RNA - Peritubular cells [nTPM]":"65.8","Single Cell Type RNA - Plasma cells [nTPM]":"44.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"55.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"82.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"61.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"56.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"25.1","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"38.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"56.6","Single Cell Type RNA - Spermatocytes [nTPM]":"10.5","Single Cell Type RNA - Spermatogonia [nTPM]":"34.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"51.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"42.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"71.1","Single Cell Type RNA - T-cells [nTPM]":"34.6","Single Cell Type RNA - Theca cells [nTPM]":"56.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"68.2","Single Cell Type RNA - Urothelial cells [nTPM]":"55.4"},{"Gene":"UBE2A","Gene synonym":["HHR6A","HR6A","RAD6A","UBC2"],"Ensembl":"ENSG00000077721","Gene description":"Ubiquitin conjugating enzyme E2 A","Uniprot":["P49459"],"Chromosome":"X","Position":"119574536-119591083","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Ubl conjugation pathway"],"Molecular function":["Chromatin regulator","Transferase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"508.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003875","HPA051765","HPA065898"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"HPA003875":"AB_2667061","HPA051765":"AB_2681597","HPA065898":"AB_2685577"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.16e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.07e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.20e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Tissue RNA - adipose tissue [nTPM]":"40.0","Tissue RNA - adrenal gland [nTPM]":"27.4","Tissue RNA - amygdala [nTPM]":"30.1","Tissue RNA - appendix [nTPM]":"39.1","Tissue RNA - basal ganglia [nTPM]":"30.6","Tissue RNA - bone marrow [nTPM]":"29.8","Tissue RNA - breast [nTPM]":"29.4","Tissue RNA - cerebellum [nTPM]":"34.1","Tissue RNA - cerebral cortex [nTPM]":"38.8","Tissue RNA - cervix [nTPM]":"34.1","Tissue RNA - choroid plexus [nTPM]":"27.1","Tissue RNA - colon [nTPM]":"52.3","Tissue RNA - duodenum [nTPM]":"37.5","Tissue RNA - endometrium 1 [nTPM]":"32.0","Tissue RNA - epididymis [nTPM]":"38.2","Tissue RNA - esophagus [nTPM]":"53.4","Tissue RNA - fallopian tube [nTPM]":"27.3","Tissue RNA - gallbladder [nTPM]":"32.6","Tissue RNA - heart muscle [nTPM]":"63.2","Tissue RNA - hippocampal formation [nTPM]":"29.6","Tissue RNA - hypothalamus [nTPM]":"32.2","Tissue RNA - kidney [nTPM]":"41.0","Tissue RNA - liver [nTPM]":"30.1","Tissue RNA - lung [nTPM]":"32.9","Tissue RNA - lymph node [nTPM]":"46.9","Tissue RNA - medulla oblongata [nTPM]":"34.4","Tissue RNA - midbrain [nTPM]":"32.5","Tissue RNA - ovary [nTPM]":"20.1","Tissue RNA - pancreas [nTPM]":"29.2","Tissue RNA - parathyroid gland [nTPM]":"39.2","Tissue RNA - pituitary gland [nTPM]":"18.9","Tissue RNA - placenta [nTPM]":"56.8","Tissue RNA - pons [nTPM]":"34.4","Tissue RNA - prostate [nTPM]":"31.0","Tissue RNA - rectum [nTPM]":"45.0","Tissue RNA - retina [nTPM]":"27.1","Tissue RNA - salivary gland [nTPM]":"30.9","Tissue RNA - seminal vesicle [nTPM]":"33.0","Tissue RNA - skeletal muscle [nTPM]":"71.9","Tissue RNA - skin 1 [nTPM]":"30.7","Tissue RNA - small intestine [nTPM]":"39.1","Tissue RNA - smooth muscle [nTPM]":"43.0","Tissue RNA - spinal cord [nTPM]":"32.1","Tissue RNA - spleen [nTPM]":"26.8","Tissue RNA - stomach 1 [nTPM]":"30.5","Tissue RNA - testis [nTPM]":"17.6","Tissue RNA - thalamus [nTPM]":"32.1","Tissue RNA - thymus [nTPM]":"46.1","Tissue RNA - thyroid gland [nTPM]":"30.5","Tissue RNA - tongue [nTPM]":"55.0","Tissue RNA - tonsil [nTPM]":"50.4","Tissue RNA - urinary bladder [nTPM]":"46.9","Tissue RNA - vagina [nTPM]":"32.8","Tissue RNA - white matter [nTPM]":"35.1","Cell RNA - A-431 [nTPM]":"129.5","Cell RNA - A549 [nTPM]":"104.1","Cell RNA - AF22 [nTPM]":"60.8","Cell RNA - AN3-CA [nTPM]":"54.1","Cell RNA - ASC diff [nTPM]":"103.0","Cell RNA - ASC TERT1 [nTPM]":"125.6","Cell RNA - BEWO [nTPM]":"63.9","Cell RNA - BJ [nTPM]":"122.6","Cell RNA - BJ hTERT+ [nTPM]":"106.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"141.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"130.3","Cell RNA - CACO-2 [nTPM]":"50.8","Cell RNA - CAPAN-2 [nTPM]":"84.0","Cell RNA - Daudi [nTPM]":"96.4","Cell RNA - EFO-21 [nTPM]":"126.4","Cell RNA - fHDF\/TERT166 [nTPM]":"133.9","Cell RNA - GAMG [nTPM]":"240.6","Cell RNA - HaCaT [nTPM]":"86.4","Cell RNA - HAP1 [nTPM]":"86.3","Cell RNA - HBEC3-KT [nTPM]":"65.7","Cell RNA - HBF TERT88 [nTPM]":"128.6","Cell RNA - HDLM-2 [nTPM]":"142.3","Cell RNA - HEK 293 [nTPM]":"60.6","Cell RNA - HEL [nTPM]":"42.7","Cell RNA - HeLa [nTPM]":"71.9","Cell RNA - Hep G2 [nTPM]":"47.1","Cell RNA - HHSteC [nTPM]":"96.6","Cell RNA - HL-60 [nTPM]":"105.9","Cell RNA - HMC-1 [nTPM]":"72.1","Cell RNA - HSkMC [nTPM]":"86.9","Cell RNA - hTCEpi [nTPM]":"90.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"134.0","Cell RNA - hTERT-HME1 [nTPM]":"58.3","Cell RNA - hTERT-RPE1 [nTPM]":"98.1","Cell RNA - HUVEC TERT2 [nTPM]":"99.4","Cell RNA - JURKAT [nTPM]":"86.5","Cell RNA - K-562 [nTPM]":"57.0","Cell RNA - Karpas-707 [nTPM]":"83.6","Cell RNA - LHCN-M2 [nTPM]":"160.1","Cell RNA - MCF7 [nTPM]":"134.5","Cell RNA - MOLT-4 [nTPM]":"166.6","Cell RNA - NB-4 [nTPM]":"99.9","Cell RNA - NTERA-2 [nTPM]":"106.3","Cell RNA - OE19 [nTPM]":"125.7","Cell RNA - PC-3 [nTPM]":"126.9","Cell RNA - REH [nTPM]":"84.2","Cell RNA - RH-30 [nTPM]":"64.0","Cell RNA - RPMI-8226 [nTPM]":"91.6","Cell RNA - RPTEC TERT1 [nTPM]":"113.1","Cell RNA - RT4 [nTPM]":"76.6","Cell RNA - SCLC-21H [nTPM]":"48.9","Cell RNA - SH-SY5Y [nTPM]":"51.3","Cell RNA - SiHa [nTPM]":"171.2","Cell RNA - SK-BR-3 [nTPM]":"75.0","Cell RNA - SK-MEL-30 [nTPM]":"93.7","Cell RNA - SuSa [nTPM]":"73.2","Cell RNA - T-47d [nTPM]":"65.8","Cell RNA - THP-1 [nTPM]":"92.6","Cell RNA - TIME [nTPM]":"101.5","Cell RNA - U-138 MG [nTPM]":"92.4","Cell RNA - U-2 OS [nTPM]":"42.0","Cell RNA - U-2197 [nTPM]":"184.3","Cell RNA - U-251 MG [nTPM]":"142.5","Cell RNA - U-266\/70 [nTPM]":"83.6","Cell RNA - U-266\/84 [nTPM]":"147.1","Cell RNA - U-698 [nTPM]":"92.4","Cell RNA - U-87 MG [nTPM]":"99.1","Cell RNA - U-937 [nTPM]":"136.3","Cell RNA - WM-115 [nTPM]":"74.6","Blood RNA - basophil [nTPM]":"46.8","Blood RNA - classical monocyte [nTPM]":"58.5","Blood RNA - eosinophil [nTPM]":"92.5","Blood RNA - gdT-cell [nTPM]":"43.0","Blood RNA - intermediate monocyte [nTPM]":"92.1","Blood RNA - MAIT T-cell [nTPM]":"34.8","Blood RNA - memory B-cell [nTPM]":"52.6","Blood RNA - memory CD4 T-cell [nTPM]":"37.9","Blood RNA - memory CD8 T-cell [nTPM]":"38.5","Blood RNA - myeloid DC [nTPM]":"74.6","Blood RNA - naive B-cell [nTPM]":"48.7","Blood RNA - naive CD4 T-cell [nTPM]":"23.7","Blood RNA - naive CD8 T-cell [nTPM]":"33.9","Blood RNA - neutrophil [nTPM]":"78.0","Blood RNA - NK-cell [nTPM]":"35.0","Blood RNA - non-classical monocyte [nTPM]":"101.1","Blood RNA - plasmacytoid DC [nTPM]":"58.5","Blood RNA - T-reg [nTPM]":"56.8","Blood RNA - total PBMC [nTPM]":"51.1","Brain RNA - amygdala [nTPM]":"30.1","Brain RNA - basal ganglia [nTPM]":"30.6","Brain RNA - cerebellum [nTPM]":"34.1","Brain RNA - cerebral cortex [nTPM]":"38.8","Brain RNA - hippocampal formation [nTPM]":"29.6","Brain RNA - hypothalamus [nTPM]":"32.2","Brain RNA - medulla oblongata [nTPM]":"34.4","Brain RNA - midbrain [nTPM]":"32.5","Brain RNA - pons [nTPM]":"34.4","Brain RNA - spinal cord [nTPM]":"32.1","Brain RNA - thalamus [nTPM]":"32.1","Brain RNA - white matter [nTPM]":"35.1","Single Cell Type RNA - Adipocytes [nTPM]":"67.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"102.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"40.9","Single Cell Type RNA - Astrocytes [nTPM]":"12.7","Single Cell Type RNA - B-cells [nTPM]":"79.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"124.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"91.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"129.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"51.8","Single Cell Type RNA - Bipolar cells [nTPM]":"17.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"60.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"43.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"66.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"44.3","Single Cell Type RNA - Club cells [nTPM]":"80.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"179.8","Single Cell Type RNA - dendritic cells [nTPM]":"93.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"168.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"101.8","Single Cell Type RNA - Ductal cells [nTPM]":"95.4","Single Cell Type RNA - Early spermatids [nTPM]":"51.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"75.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"55.3","Single Cell Type RNA - Endothelial cells [nTPM]":"62.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"45.5","Single Cell Type RNA - Erythroid cells [nTPM]":"70.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"102.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"176.2","Single Cell Type RNA - Fibroblasts [nTPM]":"67.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"37.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"63.0","Single Cell Type RNA - granulocytes [nTPM]":"57.0","Single Cell Type RNA - Granulosa cells [nTPM]":"35.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"46.4","Single Cell Type RNA - Hepatocytes [nTPM]":"35.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"131.3","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"49.7","Single Cell Type RNA - Ionocytes [nTPM]":"103.7","Single Cell Type RNA - Kupffer cells [nTPM]":"59.1","Single Cell Type RNA - Langerhans cells [nTPM]":"183.9","Single Cell Type RNA - Late spermatids [nTPM]":"15.3","Single Cell Type RNA - Leydig cells [nTPM]":"37.0","Single Cell Type RNA - Macrophages [nTPM]":"97.3","Single Cell Type RNA - Melanocytes [nTPM]":"83.6","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"129.0","Single Cell Type RNA - Muller glia cells [nTPM]":"49.8","Single Cell Type RNA - NK-cells [nTPM]":"41.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"137.6","Single Cell Type RNA - Paneth cells [nTPM]":"132.5","Single Cell Type RNA - Peritubular cells [nTPM]":"40.6","Single Cell Type RNA - Plasma cells [nTPM]":"92.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"98.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"85.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"125.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"107.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"35.0","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"56.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"101.1","Single Cell Type RNA - Spermatocytes [nTPM]":"44.1","Single Cell Type RNA - Spermatogonia [nTPM]":"32.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"74.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"127.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"508.5","Single Cell Type RNA - T-cells [nTPM]":"94.8","Single Cell Type RNA - Theca cells [nTPM]":"36.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"54.5","Single Cell Type RNA - Urothelial cells [nTPM]":"120.3"},{"Gene":"UBE2QL1","Gene synonym":["FLJ25076"],"Ensembl":"ENSG00000215218","Gene description":"Ubiquitin conjugating enzyme E2 Q family like 1","Uniprot":["A1L167"],"Chromosome":"5","Position":"6448859-6496723","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"26.1","heart muscle":"16.8","retina":"28.3","skeletal muscle":"54.5","tongue":"13.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"30.0","Cardiomyocytes":"27.6","Excitatory neurons":"47.8","Granulosa cells":"45.5","Horizontal cells":"45.4","Inhibitory neurons":"35.3","Rod photoreceptor cells":"63.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"5.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"29.7","PC-3":"24.6","SCLC-21H":"23.1","U-266\/70":"54.4","U-266\/84":"52.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057414"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA057414":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.81e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.2","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"14.3","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"14.6","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.1","Tissue RNA - cerebellum [nTPM]":"16.5","Tissue RNA - cerebral cortex [nTPM]":"26.1","Tissue RNA - cervix [nTPM]":"2.1","Tissue RNA - choroid plexus [nTPM]":"1.8","Tissue RNA - colon [nTPM]":"5.3","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.8","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.7","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"16.8","Tissue RNA - hippocampal formation [nTPM]":"17.9","Tissue RNA - hypothalamus [nTPM]":"11.4","Tissue RNA - kidney [nTPM]":"3.4","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"12.0","Tissue RNA - midbrain [nTPM]":"7.9","Tissue RNA - ovary [nTPM]":"2.6","Tissue RNA - pancreas [nTPM]":"0.6","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"3.2","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"11.6","Tissue RNA - prostate [nTPM]":"3.5","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"28.3","Tissue RNA - salivary gland [nTPM]":"0.8","Tissue RNA - seminal vesicle [nTPM]":"5.5","Tissue RNA - skeletal muscle [nTPM]":"54.5","Tissue RNA - skin 1 [nTPM]":"1.5","Tissue RNA - small intestine [nTPM]":"1.4","Tissue RNA - smooth muscle [nTPM]":"0.7","Tissue RNA - spinal cord [nTPM]":"5.6","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"2.9","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"10.1","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"1.2","Tissue RNA - tongue [nTPM]":"13.9","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"1.3","Tissue RNA - white matter [nTPM]":"17.7","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"29.7","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"5.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"24.6","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"11.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"23.1","Cell RNA - SH-SY5Y [nTPM]":"4.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"54.4","Cell RNA - U-266\/84 [nTPM]":"52.2","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"14.3","Brain RNA - basal ganglia [nTPM]":"14.6","Brain RNA - cerebellum [nTPM]":"16.5","Brain RNA - cerebral cortex [nTPM]":"26.1","Brain RNA - hippocampal formation [nTPM]":"17.9","Brain RNA - hypothalamus [nTPM]":"11.4","Brain RNA - medulla oblongata [nTPM]":"12.0","Brain RNA - midbrain [nTPM]":"7.9","Brain RNA - pons [nTPM]":"11.6","Brain RNA - spinal cord [nTPM]":"5.6","Brain RNA - thalamus [nTPM]":"10.1","Brain RNA - white matter [nTPM]":"17.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"30.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"27.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"47.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"3.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"45.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"1.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"35.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"4.1","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"9.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"1.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"63.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"UBE2T","Gene synonym":["FANCT","HSPC150"],"Ensembl":"ENSG00000077152","Gene description":"Ubiquitin conjugating enzyme E2 T","Uniprot":["Q9NPD8"],"Chromosome":"1","Position":"202331657-202341980","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Fanconi anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"47.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"74.5","Erythroid cells":"134.3","Extravillous trophoblasts":"103.4","Spermatocytes":"114.1","Spermatogonia":"113.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002831"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA002831":"AB_1080445"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.79e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.90e-6"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.22e-16"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.3","Tissue RNA - adrenal gland [nTPM]":"3.7","Tissue RNA - amygdala [nTPM]":"6.6","Tissue RNA - appendix [nTPM]":"10.4","Tissue RNA - basal ganglia [nTPM]":"6.5","Tissue RNA - bone marrow [nTPM]":"28.7","Tissue RNA - breast [nTPM]":"4.5","Tissue RNA - cerebellum [nTPM]":"5.8","Tissue RNA - cerebral cortex [nTPM]":"13.7","Tissue RNA - cervix [nTPM]":"4.1","Tissue RNA - choroid plexus [nTPM]":"5.0","Tissue RNA - colon [nTPM]":"13.1","Tissue RNA - duodenum [nTPM]":"8.7","Tissue RNA - endometrium 1 [nTPM]":"4.5","Tissue RNA - epididymis [nTPM]":"4.4","Tissue RNA - esophagus [nTPM]":"10.6","Tissue RNA - fallopian tube [nTPM]":"3.3","Tissue RNA - gallbladder [nTPM]":"2.5","Tissue RNA - heart muscle [nTPM]":"11.3","Tissue RNA - hippocampal formation [nTPM]":"6.8","Tissue RNA - hypothalamus [nTPM]":"7.4","Tissue RNA - kidney [nTPM]":"3.5","Tissue RNA - liver [nTPM]":"3.2","Tissue RNA - lung [nTPM]":"3.0","Tissue RNA - lymph node [nTPM]":"19.0","Tissue RNA - medulla oblongata [nTPM]":"6.5","Tissue RNA - midbrain [nTPM]":"6.6","Tissue RNA - ovary [nTPM]":"1.0","Tissue RNA - pancreas [nTPM]":"0.7","Tissue RNA - parathyroid gland [nTPM]":"4.4","Tissue RNA - pituitary gland [nTPM]":"3.0","Tissue RNA - placenta [nTPM]":"10.1","Tissue RNA - pons [nTPM]":"6.9","Tissue RNA - prostate [nTPM]":"2.1","Tissue RNA - rectum [nTPM]":"15.5","Tissue RNA - retina [nTPM]":"2.5","Tissue RNA - salivary gland [nTPM]":"2.7","Tissue RNA - seminal vesicle [nTPM]":"3.1","Tissue RNA - skeletal muscle [nTPM]":"17.2","Tissue RNA - skin 1 [nTPM]":"5.3","Tissue RNA - small intestine [nTPM]":"8.2","Tissue RNA - smooth muscle [nTPM]":"9.4","Tissue RNA - spinal cord [nTPM]":"6.0","Tissue RNA - spleen [nTPM]":"6.2","Tissue RNA - stomach 1 [nTPM]":"4.7","Tissue RNA - testis [nTPM]":"19.3","Tissue RNA - thalamus [nTPM]":"6.7","Tissue RNA - thymus [nTPM]":"47.1","Tissue RNA - thyroid gland [nTPM]":"2.9","Tissue RNA - tongue [nTPM]":"13.0","Tissue RNA - tonsil [nTPM]":"18.6","Tissue RNA - urinary bladder [nTPM]":"6.3","Tissue RNA - vagina [nTPM]":"5.0","Tissue RNA - white matter [nTPM]":"6.1","Cell RNA - A-431 [nTPM]":"123.3","Cell RNA - A549 [nTPM]":"111.6","Cell RNA - AF22 [nTPM]":"167.1","Cell RNA - AN3-CA [nTPM]":"79.8","Cell RNA - ASC diff [nTPM]":"15.4","Cell RNA - ASC TERT1 [nTPM]":"27.9","Cell RNA - BEWO [nTPM]":"94.2","Cell RNA - BJ [nTPM]":"130.2","Cell RNA - BJ hTERT+ [nTPM]":"72.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"146.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"102.6","Cell RNA - CACO-2 [nTPM]":"79.9","Cell RNA - CAPAN-2 [nTPM]":"147.1","Cell RNA - Daudi [nTPM]":"140.4","Cell RNA - EFO-21 [nTPM]":"50.0","Cell RNA - fHDF\/TERT166 [nTPM]":"47.0","Cell RNA - GAMG [nTPM]":"108.4","Cell RNA - HaCaT [nTPM]":"98.6","Cell RNA - HAP1 [nTPM]":"154.1","Cell RNA - HBEC3-KT [nTPM]":"76.7","Cell RNA - HBF TERT88 [nTPM]":"131.2","Cell RNA - HDLM-2 [nTPM]":"128.1","Cell RNA - HEK 293 [nTPM]":"87.2","Cell RNA - HEL [nTPM]":"85.6","Cell RNA - HeLa [nTPM]":"54.0","Cell RNA - Hep G2 [nTPM]":"93.8","Cell RNA - HHSteC [nTPM]":"6.9","Cell RNA - HL-60 [nTPM]":"105.2","Cell RNA - HMC-1 [nTPM]":"102.0","Cell RNA - HSkMC [nTPM]":"9.8","Cell RNA - hTCEpi [nTPM]":"18.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"114.0","Cell RNA - hTERT-HME1 [nTPM]":"47.2","Cell RNA - hTERT-RPE1 [nTPM]":"34.3","Cell RNA - HUVEC TERT2 [nTPM]":"85.8","Cell RNA - JURKAT [nTPM]":"157.4","Cell RNA - K-562 [nTPM]":"111.0","Cell RNA - Karpas-707 [nTPM]":"114.0","Cell RNA - LHCN-M2 [nTPM]":"116.4","Cell RNA - MCF7 [nTPM]":"113.3","Cell RNA - MOLT-4 [nTPM]":"190.8","Cell RNA - NB-4 [nTPM]":"135.1","Cell RNA - NTERA-2 [nTPM]":"65.4","Cell RNA - OE19 [nTPM]":"126.9","Cell RNA - PC-3 [nTPM]":"57.4","Cell RNA - REH [nTPM]":"145.0","Cell RNA - RH-30 [nTPM]":"176.2","Cell RNA - RPMI-8226 [nTPM]":"122.9","Cell RNA - RPTEC TERT1 [nTPM]":"57.1","Cell RNA - RT4 [nTPM]":"58.1","Cell RNA - SCLC-21H [nTPM]":"131.3","Cell RNA - SH-SY5Y [nTPM]":"132.8","Cell RNA - SiHa [nTPM]":"90.2","Cell RNA - SK-BR-3 [nTPM]":"112.1","Cell RNA - SK-MEL-30 [nTPM]":"44.8","Cell RNA - SuSa [nTPM]":"49.8","Cell RNA - T-47d [nTPM]":"117.1","Cell RNA - THP-1 [nTPM]":"64.6","Cell RNA - TIME [nTPM]":"41.8","Cell RNA - U-138 MG [nTPM]":"65.7","Cell RNA - U-2 OS [nTPM]":"104.6","Cell RNA - U-2197 [nTPM]":"116.1","Cell RNA - U-251 MG [nTPM]":"159.6","Cell RNA - U-266\/70 [nTPM]":"57.8","Cell RNA - U-266\/84 [nTPM]":"120.1","Cell RNA - U-698 [nTPM]":"182.9","Cell RNA - U-87 MG [nTPM]":"64.5","Cell RNA - U-937 [nTPM]":"107.0","Cell RNA - WM-115 [nTPM]":"139.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.7","Blood RNA - eosinophil [nTPM]":"1.7","Blood RNA - gdT-cell [nTPM]":"3.3","Blood RNA - intermediate monocyte [nTPM]":"2.3","Blood RNA - MAIT T-cell [nTPM]":"2.5","Blood RNA - memory B-cell [nTPM]":"8.5","Blood RNA - memory CD4 T-cell [nTPM]":"4.5","Blood RNA - memory CD8 T-cell [nTPM]":"3.3","Blood RNA - myeloid DC [nTPM]":"1.7","Blood RNA - naive B-cell [nTPM]":"6.6","Blood RNA - naive CD4 T-cell [nTPM]":"6.4","Blood RNA - naive CD8 T-cell [nTPM]":"7.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.2","Blood RNA - non-classical monocyte [nTPM]":"8.9","Blood RNA - plasmacytoid DC [nTPM]":"3.4","Blood RNA - T-reg [nTPM]":"10.8","Blood RNA - total PBMC [nTPM]":"2.4","Brain RNA - amygdala [nTPM]":"6.6","Brain RNA - basal ganglia [nTPM]":"6.5","Brain RNA - cerebellum [nTPM]":"5.8","Brain RNA - cerebral cortex [nTPM]":"13.7","Brain RNA - hippocampal formation [nTPM]":"6.8","Brain RNA - hypothalamus [nTPM]":"7.4","Brain RNA - medulla oblongata [nTPM]":"6.5","Brain RNA - midbrain [nTPM]":"6.6","Brain RNA - pons [nTPM]":"6.9","Brain RNA - spinal cord [nTPM]":"6.0","Brain RNA - thalamus [nTPM]":"6.7","Brain RNA - white matter [nTPM]":"6.1","Single Cell Type RNA - Adipocytes [nTPM]":"1.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.2","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"13.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"6.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"12.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"74.5","Single Cell Type RNA - dendritic cells [nTPM]":"5.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"10.9","Single Cell Type RNA - Early spermatids [nTPM]":"24.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.6","Single Cell Type RNA - Endothelial cells [nTPM]":"5.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"134.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"103.4","Single Cell Type RNA - Fibroblasts [nTPM]":"11.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.7","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"32.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"2.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"27.7","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.4","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"5.4","Single Cell Type RNA - Late spermatids [nTPM]":"8.2","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"5.8","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"2.6","Single Cell Type RNA - Muller glia cells [nTPM]":"1.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.3","Single Cell Type RNA - Paneth cells [nTPM]":"2.9","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"32.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.3","Single Cell Type RNA - Spermatocytes [nTPM]":"114.1","Single Cell Type RNA - Spermatogonia [nTPM]":"113.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.4","Single Cell Type RNA - T-cells [nTPM]":"9.3","Single Cell Type RNA - Theca cells [nTPM]":"12.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"30.5","Single Cell Type RNA - Urothelial cells [nTPM]":"11.3"},{"Gene":"UBE3A","Gene synonym":["ANCR","AS","E6-AP","EPVE6AP","FLJ26981","HPVE6A"],"Ensembl":"ENSG00000114062","Gene description":"Ubiquitin protein ligase E3A","Uniprot":["Q05086"],"Chromosome":"15","Position":"25333728-25439051","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Biological rhythms","Host-virus interaction","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009723","HPA039410","HPA040380"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB009723":"AB_639982","HPA039410":"AB_10671997","HPA040380":"AB_2676952"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-2"},"Tissue RNA - adipose tissue [nTPM]":"29.1","Tissue RNA - adrenal gland [nTPM]":"29.0","Tissue RNA - amygdala [nTPM]":"28.0","Tissue RNA - appendix [nTPM]":"27.6","Tissue RNA - basal ganglia [nTPM]":"30.3","Tissue RNA - bone marrow [nTPM]":"32.4","Tissue RNA - breast [nTPM]":"32.6","Tissue RNA - cerebellum [nTPM]":"42.8","Tissue RNA - cerebral cortex [nTPM]":"41.7","Tissue RNA - cervix [nTPM]":"33.5","Tissue RNA - choroid plexus [nTPM]":"14.0","Tissue RNA - colon [nTPM]":"33.5","Tissue RNA - duodenum [nTPM]":"22.9","Tissue RNA - endometrium 1 [nTPM]":"32.9","Tissue RNA - epididymis [nTPM]":"29.5","Tissue RNA - esophagus [nTPM]":"32.9","Tissue RNA - fallopian tube [nTPM]":"29.9","Tissue RNA - gallbladder [nTPM]":"24.5","Tissue RNA - heart muscle [nTPM]":"40.6","Tissue RNA - hippocampal formation [nTPM]":"31.0","Tissue RNA - hypothalamus [nTPM]":"28.2","Tissue RNA - kidney [nTPM]":"32.6","Tissue RNA - liver [nTPM]":"42.2","Tissue RNA - lung [nTPM]":"24.9","Tissue RNA - lymph node [nTPM]":"33.3","Tissue RNA - medulla oblongata [nTPM]":"22.3","Tissue RNA - midbrain [nTPM]":"23.6","Tissue RNA - ovary [nTPM]":"37.1","Tissue RNA - pancreas [nTPM]":"27.2","Tissue RNA - parathyroid gland [nTPM]":"38.4","Tissue RNA - pituitary gland [nTPM]":"15.3","Tissue RNA - placenta [nTPM]":"28.4","Tissue RNA - pons [nTPM]":"24.0","Tissue RNA - prostate [nTPM]":"31.8","Tissue RNA - rectum [nTPM]":"28.9","Tissue RNA - retina [nTPM]":"32.8","Tissue RNA - salivary gland [nTPM]":"23.3","Tissue RNA - seminal vesicle [nTPM]":"28.4","Tissue RNA - skeletal muscle [nTPM]":"109.2","Tissue RNA - skin 1 [nTPM]":"26.8","Tissue RNA - small intestine [nTPM]":"29.5","Tissue RNA - smooth muscle [nTPM]":"30.9","Tissue RNA - spinal cord [nTPM]":"19.9","Tissue RNA - spleen [nTPM]":"26.9","Tissue RNA - stomach 1 [nTPM]":"26.1","Tissue RNA - testis [nTPM]":"45.6","Tissue RNA - thalamus [nTPM]":"28.1","Tissue RNA - thymus [nTPM]":"41.7","Tissue RNA - thyroid gland [nTPM]":"41.5","Tissue RNA - tongue [nTPM]":"92.0","Tissue RNA - tonsil [nTPM]":"34.2","Tissue RNA - urinary bladder [nTPM]":"32.8","Tissue RNA - vagina [nTPM]":"20.0","Tissue RNA - white matter [nTPM]":"29.2","Cell RNA - A-431 [nTPM]":"55.9","Cell RNA - A549 [nTPM]":"33.6","Cell RNA - AF22 [nTPM]":"77.7","Cell RNA - AN3-CA [nTPM]":"46.1","Cell RNA - ASC diff [nTPM]":"45.0","Cell RNA - ASC TERT1 [nTPM]":"56.4","Cell RNA - BEWO [nTPM]":"38.4","Cell RNA - BJ [nTPM]":"84.8","Cell RNA - BJ hTERT+ [nTPM]":"54.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"59.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"55.6","Cell RNA - CACO-2 [nTPM]":"76.0","Cell RNA - CAPAN-2 [nTPM]":"27.6","Cell RNA - Daudi [nTPM]":"103.4","Cell RNA - EFO-21 [nTPM]":"61.2","Cell RNA - fHDF\/TERT166 [nTPM]":"68.2","Cell RNA - GAMG [nTPM]":"57.8","Cell RNA - HaCaT [nTPM]":"51.2","Cell RNA - HAP1 [nTPM]":"106.8","Cell RNA - HBEC3-KT [nTPM]":"62.2","Cell RNA - HBF TERT88 [nTPM]":"75.2","Cell RNA - HDLM-2 [nTPM]":"54.1","Cell RNA - HEK 293 [nTPM]":"32.7","Cell RNA - HEL [nTPM]":"85.8","Cell RNA - HeLa [nTPM]":"49.0","Cell RNA - Hep G2 [nTPM]":"43.1","Cell RNA - HHSteC [nTPM]":"65.5","Cell RNA - HL-60 [nTPM]":"107.0","Cell RNA - HMC-1 [nTPM]":"60.2","Cell RNA - HSkMC [nTPM]":"60.6","Cell RNA - hTCEpi [nTPM]":"56.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"58.3","Cell RNA - hTERT-HME1 [nTPM]":"71.6","Cell RNA - hTERT-RPE1 [nTPM]":"60.0","Cell RNA - HUVEC TERT2 [nTPM]":"47.6","Cell RNA - JURKAT [nTPM]":"87.0","Cell RNA - K-562 [nTPM]":"89.0","Cell RNA - Karpas-707 [nTPM]":"71.1","Cell RNA - LHCN-M2 [nTPM]":"95.1","Cell RNA - MCF7 [nTPM]":"32.3","Cell RNA - MOLT-4 [nTPM]":"84.0","Cell RNA - NB-4 [nTPM]":"29.1","Cell RNA - NTERA-2 [nTPM]":"50.3","Cell RNA - OE19 [nTPM]":"62.1","Cell RNA - PC-3 [nTPM]":"46.6","Cell RNA - REH [nTPM]":"88.6","Cell RNA - RH-30 [nTPM]":"117.8","Cell RNA - RPMI-8226 [nTPM]":"45.6","Cell RNA - RPTEC TERT1 [nTPM]":"51.7","Cell RNA - RT4 [nTPM]":"91.1","Cell RNA - SCLC-21H [nTPM]":"80.0","Cell RNA - SH-SY5Y [nTPM]":"59.6","Cell RNA - SiHa [nTPM]":"72.1","Cell RNA - SK-BR-3 [nTPM]":"72.1","Cell RNA - SK-MEL-30 [nTPM]":"102.1","Cell RNA - SuSa [nTPM]":"51.3","Cell RNA - T-47d [nTPM]":"57.9","Cell RNA - THP-1 [nTPM]":"56.7","Cell RNA - TIME [nTPM]":"59.2","Cell RNA - U-138 MG [nTPM]":"102.1","Cell RNA - U-2 OS [nTPM]":"84.7","Cell RNA - U-2197 [nTPM]":"52.1","Cell RNA - U-251 MG [nTPM]":"64.5","Cell RNA - U-266\/70 [nTPM]":"77.5","Cell RNA - U-266\/84 [nTPM]":"103.4","Cell RNA - U-698 [nTPM]":"139.5","Cell RNA - U-87 MG [nTPM]":"60.4","Cell RNA - U-937 [nTPM]":"56.6","Cell RNA - WM-115 [nTPM]":"55.3","Blood RNA - basophil [nTPM]":"14.4","Blood RNA - classical monocyte [nTPM]":"12.7","Blood RNA - eosinophil [nTPM]":"17.2","Blood RNA - gdT-cell [nTPM]":"17.0","Blood RNA - intermediate monocyte [nTPM]":"11.2","Blood RNA - MAIT T-cell [nTPM]":"19.9","Blood RNA - memory B-cell [nTPM]":"17.3","Blood RNA - memory CD4 T-cell [nTPM]":"18.5","Blood RNA - memory CD8 T-cell [nTPM]":"20.8","Blood RNA - myeloid DC [nTPM]":"16.7","Blood RNA - naive B-cell [nTPM]":"22.8","Blood RNA - naive CD4 T-cell [nTPM]":"20.8","Blood RNA - naive CD8 T-cell [nTPM]":"18.7","Blood RNA - neutrophil [nTPM]":"2.2","Blood RNA - NK-cell [nTPM]":"29.6","Blood RNA - non-classical monocyte [nTPM]":"22.3","Blood RNA - plasmacytoid DC [nTPM]":"15.2","Blood RNA - T-reg [nTPM]":"15.8","Blood RNA - total PBMC [nTPM]":"9.7","Brain RNA - amygdala [nTPM]":"28.0","Brain RNA - basal ganglia [nTPM]":"30.3","Brain RNA - cerebellum [nTPM]":"42.8","Brain RNA - cerebral cortex [nTPM]":"41.7","Brain RNA - hippocampal formation [nTPM]":"31.0","Brain RNA - hypothalamus [nTPM]":"28.2","Brain RNA - medulla oblongata [nTPM]":"22.3","Brain RNA - midbrain [nTPM]":"23.6","Brain RNA - pons [nTPM]":"24.0","Brain RNA - spinal cord [nTPM]":"19.9","Brain RNA - thalamus [nTPM]":"28.1","Brain RNA - white matter [nTPM]":"29.2","Single Cell Type RNA - Adipocytes [nTPM]":"56.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"96.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"80.5","Single Cell Type RNA - Astrocytes [nTPM]":"112.6","Single Cell Type RNA - B-cells [nTPM]":"74.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"71.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"83.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"40.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"84.2","Single Cell Type RNA - Bipolar cells [nTPM]":"82.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"59.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"42.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"175.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"42.9","Single Cell Type RNA - Club cells [nTPM]":"58.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"56.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"52.3","Single Cell Type RNA - dendritic cells [nTPM]":"74.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"43.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"51.6","Single Cell Type RNA - Early spermatids [nTPM]":"139.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"53.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"75.2","Single Cell Type RNA - Endothelial cells [nTPM]":"58.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"68.7","Single Cell Type RNA - Erythroid cells [nTPM]":"64.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"187.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"49.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"49.6","Single Cell Type RNA - Fibroblasts [nTPM]":"64.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"52.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"63.8","Single Cell Type RNA - granulocytes [nTPM]":"62.8","Single Cell Type RNA - Granulosa cells [nTPM]":"84.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"44.3","Single Cell Type RNA - Hepatocytes [nTPM]":"58.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"46.0","Single Cell Type RNA - Horizontal cells [nTPM]":"80.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"196.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"55.0","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"60.9","Single Cell Type RNA - Langerhans cells [nTPM]":"41.1","Single Cell Type RNA - Late spermatids [nTPM]":"61.6","Single Cell Type RNA - Leydig cells [nTPM]":"56.8","Single Cell Type RNA - Macrophages [nTPM]":"64.4","Single Cell Type RNA - Melanocytes [nTPM]":"53.4","Single Cell Type RNA - Microglial cells [nTPM]":"87.1","Single Cell Type RNA - monocytes [nTPM]":"53.3","Single Cell Type RNA - Muller glia cells [nTPM]":"54.5","Single Cell Type RNA - NK-cells [nTPM]":"54.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"126.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"124.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"59.8","Single Cell Type RNA - Paneth cells [nTPM]":"41.5","Single Cell Type RNA - Peritubular cells [nTPM]":"64.7","Single Cell Type RNA - Plasma cells [nTPM]":"95.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"102.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"51.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"50.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"59.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"59.2","Single Cell Type RNA - Sertoli cells [nTPM]":"78.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"119.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"80.5","Single Cell Type RNA - Spermatocytes [nTPM]":"146.1","Single Cell Type RNA - Spermatogonia [nTPM]":"88.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"78.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"90.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"74.0","Single Cell Type RNA - T-cells [nTPM]":"63.3","Single Cell Type RNA - Theca cells [nTPM]":"65.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"52.6","Single Cell Type RNA - Urothelial cells [nTPM]":"98.6"},{"Gene":"UBE3B","Gene synonym":[],"Ensembl":"ENSG00000151148","Gene description":"Ubiquitin protein ligase E3B","Uniprot":["Q7Z3V4"],"Chromosome":"12","Position":"109477402-109536705","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041012"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 51: Myeloid cells - Hemostasis","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"HPA041012":"AB_10964435"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.49e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Tissue RNA - adipose tissue [nTPM]":"13.8","Tissue RNA - adrenal gland [nTPM]":"16.5","Tissue RNA - amygdala [nTPM]":"14.4","Tissue RNA - appendix [nTPM]":"10.7","Tissue RNA - basal ganglia [nTPM]":"16.1","Tissue RNA - bone marrow [nTPM]":"9.2","Tissue RNA - breast [nTPM]":"13.7","Tissue RNA - cerebellum [nTPM]":"13.3","Tissue RNA - cerebral cortex [nTPM]":"15.6","Tissue RNA - cervix [nTPM]":"14.4","Tissue RNA - choroid plexus [nTPM]":"16.5","Tissue RNA - colon [nTPM]":"17.8","Tissue RNA - duodenum [nTPM]":"12.9","Tissue RNA - endometrium 1 [nTPM]":"14.1","Tissue RNA - epididymis [nTPM]":"13.4","Tissue RNA - esophagus [nTPM]":"18.6","Tissue RNA - fallopian tube [nTPM]":"16.2","Tissue RNA - gallbladder [nTPM]":"12.1","Tissue RNA - heart muscle [nTPM]":"26.2","Tissue RNA - hippocampal formation [nTPM]":"14.4","Tissue RNA - hypothalamus [nTPM]":"12.4","Tissue RNA - kidney [nTPM]":"16.7","Tissue RNA - liver [nTPM]":"16.0","Tissue RNA - lung [nTPM]":"13.6","Tissue RNA - lymph node [nTPM]":"12.6","Tissue RNA - medulla oblongata [nTPM]":"13.7","Tissue RNA - midbrain [nTPM]":"14.6","Tissue RNA - ovary [nTPM]":"15.8","Tissue RNA - pancreas [nTPM]":"14.3","Tissue RNA - parathyroid gland [nTPM]":"22.6","Tissue RNA - pituitary gland [nTPM]":"13.6","Tissue RNA - placenta [nTPM]":"13.1","Tissue RNA - pons [nTPM]":"14.8","Tissue RNA - prostate [nTPM]":"15.4","Tissue RNA - rectum [nTPM]":"18.1","Tissue RNA - retina [nTPM]":"14.9","Tissue RNA - salivary gland [nTPM]":"14.4","Tissue RNA - seminal vesicle [nTPM]":"14.1","Tissue RNA - skeletal muscle [nTPM]":"34.0","Tissue RNA - skin 1 [nTPM]":"19.2","Tissue RNA - small intestine [nTPM]":"15.8","Tissue RNA - smooth muscle [nTPM]":"14.7","Tissue RNA - spinal cord [nTPM]":"12.5","Tissue RNA - spleen [nTPM]":"15.8","Tissue RNA - stomach 1 [nTPM]":"16.5","Tissue RNA - testis [nTPM]":"12.9","Tissue RNA - thalamus [nTPM]":"16.1","Tissue RNA - thymus [nTPM]":"12.6","Tissue RNA - thyroid gland [nTPM]":"18.2","Tissue RNA - tongue [nTPM]":"29.7","Tissue RNA - tonsil [nTPM]":"13.5","Tissue RNA - urinary bladder [nTPM]":"17.0","Tissue RNA - vagina [nTPM]":"14.5","Tissue RNA - white matter [nTPM]":"20.3","Cell RNA - A-431 [nTPM]":"17.1","Cell RNA - A549 [nTPM]":"26.4","Cell RNA - AF22 [nTPM]":"20.4","Cell RNA - AN3-CA [nTPM]":"14.8","Cell RNA - ASC diff [nTPM]":"33.9","Cell RNA - ASC TERT1 [nTPM]":"27.1","Cell RNA - BEWO [nTPM]":"17.9","Cell RNA - BJ [nTPM]":"22.1","Cell RNA - BJ hTERT+ [nTPM]":"25.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"26.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.4","Cell RNA - CACO-2 [nTPM]":"28.0","Cell RNA - CAPAN-2 [nTPM]":"17.1","Cell RNA - Daudi [nTPM]":"10.6","Cell RNA - EFO-21 [nTPM]":"16.0","Cell RNA - fHDF\/TERT166 [nTPM]":"36.3","Cell RNA - GAMG [nTPM]":"22.5","Cell RNA - HaCaT [nTPM]":"21.5","Cell RNA - HAP1 [nTPM]":"20.9","Cell RNA - HBEC3-KT [nTPM]":"28.3","Cell RNA - HBF TERT88 [nTPM]":"25.1","Cell RNA - HDLM-2 [nTPM]":"23.4","Cell RNA - HEK 293 [nTPM]":"14.7","Cell RNA - HEL [nTPM]":"20.3","Cell RNA - HeLa [nTPM]":"17.6","Cell RNA - Hep G2 [nTPM]":"25.5","Cell RNA - HHSteC [nTPM]":"21.7","Cell RNA - HL-60 [nTPM]":"16.7","Cell RNA - HMC-1 [nTPM]":"16.2","Cell RNA - HSkMC [nTPM]":"31.0","Cell RNA - hTCEpi [nTPM]":"25.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.4","Cell RNA - hTERT-HME1 [nTPM]":"30.2","Cell RNA - hTERT-RPE1 [nTPM]":"39.5","Cell RNA - HUVEC TERT2 [nTPM]":"28.7","Cell RNA - JURKAT [nTPM]":"24.8","Cell RNA - K-562 [nTPM]":"22.7","Cell RNA - Karpas-707 [nTPM]":"9.7","Cell RNA - LHCN-M2 [nTPM]":"30.2","Cell RNA - MCF7 [nTPM]":"26.6","Cell RNA - MOLT-4 [nTPM]":"11.5","Cell RNA - NB-4 [nTPM]":"24.2","Cell RNA - NTERA-2 [nTPM]":"21.0","Cell RNA - OE19 [nTPM]":"19.1","Cell RNA - PC-3 [nTPM]":"31.6","Cell RNA - REH [nTPM]":"18.8","Cell RNA - RH-30 [nTPM]":"19.2","Cell RNA - RPMI-8226 [nTPM]":"20.9","Cell RNA - RPTEC TERT1 [nTPM]":"22.4","Cell RNA - RT4 [nTPM]":"30.2","Cell RNA - SCLC-21H [nTPM]":"19.1","Cell RNA - SH-SY5Y [nTPM]":"34.9","Cell RNA - SiHa [nTPM]":"25.8","Cell RNA - SK-BR-3 [nTPM]":"34.6","Cell RNA - SK-MEL-30 [nTPM]":"17.3","Cell RNA - SuSa [nTPM]":"23.7","Cell RNA - T-47d [nTPM]":"35.3","Cell RNA - THP-1 [nTPM]":"17.6","Cell RNA - TIME [nTPM]":"26.5","Cell RNA - U-138 MG [nTPM]":"32.3","Cell RNA - U-2 OS [nTPM]":"9.2","Cell RNA - U-2197 [nTPM]":"16.8","Cell RNA - U-251 MG [nTPM]":"16.0","Cell RNA - U-266\/70 [nTPM]":"21.8","Cell RNA - U-266\/84 [nTPM]":"19.4","Cell RNA - U-698 [nTPM]":"18.6","Cell RNA - U-87 MG [nTPM]":"32.1","Cell RNA - U-937 [nTPM]":"13.7","Cell RNA - WM-115 [nTPM]":"27.4","Blood RNA - basophil [nTPM]":"22.9","Blood RNA - classical monocyte [nTPM]":"12.9","Blood RNA - eosinophil [nTPM]":"12.8","Blood RNA - gdT-cell [nTPM]":"12.6","Blood RNA - intermediate monocyte [nTPM]":"14.5","Blood RNA - MAIT T-cell [nTPM]":"12.4","Blood RNA - memory B-cell [nTPM]":"13.6","Blood RNA - memory CD4 T-cell [nTPM]":"12.1","Blood RNA - memory CD8 T-cell [nTPM]":"9.0","Blood RNA - myeloid DC [nTPM]":"12.4","Blood RNA - naive B-cell [nTPM]":"10.0","Blood RNA - naive CD4 T-cell [nTPM]":"10.0","Blood RNA - naive CD8 T-cell [nTPM]":"13.3","Blood RNA - neutrophil [nTPM]":"16.1","Blood RNA - NK-cell [nTPM]":"13.1","Blood RNA - non-classical monocyte [nTPM]":"12.0","Blood RNA - plasmacytoid DC [nTPM]":"11.4","Blood RNA - T-reg [nTPM]":"16.2","Blood RNA - total PBMC [nTPM]":"10.7","Brain RNA - amygdala [nTPM]":"14.4","Brain RNA - basal ganglia [nTPM]":"16.1","Brain RNA - cerebellum [nTPM]":"13.3","Brain RNA - cerebral cortex [nTPM]":"15.6","Brain RNA - hippocampal formation [nTPM]":"14.4","Brain RNA - hypothalamus [nTPM]":"12.4","Brain RNA - medulla oblongata [nTPM]":"13.7","Brain RNA - midbrain [nTPM]":"14.6","Brain RNA - pons [nTPM]":"14.8","Brain RNA - spinal cord [nTPM]":"12.5","Brain RNA - thalamus [nTPM]":"16.1","Brain RNA - white matter [nTPM]":"20.3","Single Cell Type RNA - Adipocytes [nTPM]":"11.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.1","Single Cell Type RNA - Astrocytes [nTPM]":"34.0","Single Cell Type RNA - B-cells [nTPM]":"9.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"19.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"35.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"17.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"17.9","Single Cell Type RNA - dendritic cells [nTPM]":"12.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"21.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"17.7","Single Cell Type RNA - Early spermatids [nTPM]":"15.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.5","Single Cell Type RNA - Endothelial cells [nTPM]":"14.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.0","Single Cell Type RNA - Erythroid cells [nTPM]":"13.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"24.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.5","Single Cell Type RNA - Fibroblasts [nTPM]":"11.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.2","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"20.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"18.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.5","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"23.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.9","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"19.2","Single Cell Type RNA - Langerhans cells [nTPM]":"6.1","Single Cell Type RNA - Late spermatids [nTPM]":"32.0","Single Cell Type RNA - Leydig cells [nTPM]":"12.5","Single Cell Type RNA - Macrophages [nTPM]":"14.2","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"17.7","Single Cell Type RNA - Muller glia cells [nTPM]":"13.6","Single Cell Type RNA - NK-cells [nTPM]":"32.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"21.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"38.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"25.3","Single Cell Type RNA - Paneth cells [nTPM]":"13.7","Single Cell Type RNA - Peritubular cells [nTPM]":"9.8","Single Cell Type RNA - Plasma cells [nTPM]":"15.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"19.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.0","Single Cell Type RNA - Spermatocytes [nTPM]":"10.4","Single Cell Type RNA - Spermatogonia [nTPM]":"13.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.7","Single Cell Type RNA - T-cells [nTPM]":"10.7","Single Cell Type RNA - Theca cells [nTPM]":"17.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.8","Single Cell Type RNA - Urothelial cells [nTPM]":"18.4"},{"Gene":"UBQLN4","Gene synonym":["A1U","C1orf6","UBIN"],"Ensembl":"ENSG00000160803","Gene description":"Ubiquilin 4","Uniprot":["Q9NRR5"],"Chromosome":"1","Position":"156035299-156053798","Protein class":["Disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Autophagy","DNA damage","DNA repair"],"Molecular function":null,"Disease involvement":["Amyotrophic lateral sclerosis","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"9.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"9.7"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA061797"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA061797":"AB_2684613"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Tissue RNA - adipose tissue [nTPM]":"18.9","Tissue RNA - adrenal gland [nTPM]":"19.4","Tissue RNA - amygdala [nTPM]":"39.9","Tissue RNA - appendix [nTPM]":"14.6","Tissue RNA - basal ganglia [nTPM]":"47.9","Tissue RNA - bone marrow [nTPM]":"9.1","Tissue RNA - breast [nTPM]":"19.1","Tissue RNA - cerebellum [nTPM]":"34.3","Tissue RNA - cerebral cortex [nTPM]":"52.5","Tissue RNA - cervix [nTPM]":"31.6","Tissue RNA - choroid plexus [nTPM]":"27.3","Tissue RNA - colon [nTPM]":"24.5","Tissue RNA - duodenum [nTPM]":"13.6","Tissue RNA - endometrium 1 [nTPM]":"24.3","Tissue RNA - epididymis [nTPM]":"15.3","Tissue RNA - esophagus [nTPM]":"33.7","Tissue RNA - fallopian tube [nTPM]":"26.7","Tissue RNA - gallbladder [nTPM]":"11.5","Tissue RNA - heart muscle [nTPM]":"26.7","Tissue RNA - hippocampal formation [nTPM]":"40.8","Tissue RNA - hypothalamus [nTPM]":"40.2","Tissue RNA - kidney [nTPM]":"25.7","Tissue RNA - liver [nTPM]":"31.7","Tissue RNA - lung [nTPM]":"20.8","Tissue RNA - lymph node [nTPM]":"15.0","Tissue RNA - medulla oblongata [nTPM]":"38.1","Tissue RNA - midbrain [nTPM]":"38.3","Tissue RNA - ovary [nTPM]":"21.1","Tissue RNA - pancreas [nTPM]":"32.2","Tissue RNA - parathyroid gland [nTPM]":"25.6","Tissue RNA - pituitary gland [nTPM]":"11.3","Tissue RNA - placenta [nTPM]":"15.5","Tissue RNA - pons [nTPM]":"37.7","Tissue RNA - prostate [nTPM]":"25.4","Tissue RNA - rectum [nTPM]":"15.5","Tissue RNA - retina [nTPM]":"18.3","Tissue RNA - salivary gland [nTPM]":"23.3","Tissue RNA - seminal vesicle [nTPM]":"19.6","Tissue RNA - skeletal muscle [nTPM]":"59.7","Tissue RNA - skin 1 [nTPM]":"27.0","Tissue RNA - small intestine [nTPM]":"18.8","Tissue RNA - smooth muscle [nTPM]":"22.9","Tissue RNA - spinal cord [nTPM]":"37.1","Tissue RNA - spleen [nTPM]":"20.2","Tissue RNA - stomach 1 [nTPM]":"28.2","Tissue RNA - testis [nTPM]":"19.8","Tissue RNA - thalamus [nTPM]":"40.0","Tissue RNA - thymus [nTPM]":"14.1","Tissue RNA - thyroid gland [nTPM]":"17.7","Tissue RNA - tongue [nTPM]":"39.5","Tissue RNA - tonsil [nTPM]":"17.0","Tissue RNA - urinary bladder [nTPM]":"26.1","Tissue RNA - vagina [nTPM]":"26.0","Tissue RNA - white matter [nTPM]":"39.8","Cell RNA - A-431 [nTPM]":"45.9","Cell RNA - A549 [nTPM]":"54.1","Cell RNA - AF22 [nTPM]":"50.8","Cell RNA - AN3-CA [nTPM]":"50.1","Cell RNA - ASC diff [nTPM]":"34.1","Cell RNA - ASC TERT1 [nTPM]":"21.0","Cell RNA - BEWO [nTPM]":"50.0","Cell RNA - BJ [nTPM]":"37.8","Cell RNA - BJ hTERT+ [nTPM]":"20.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"37.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"27.8","Cell RNA - CACO-2 [nTPM]":"49.0","Cell RNA - CAPAN-2 [nTPM]":"40.5","Cell RNA - Daudi [nTPM]":"77.7","Cell RNA - EFO-21 [nTPM]":"33.9","Cell RNA - fHDF\/TERT166 [nTPM]":"34.7","Cell RNA - GAMG [nTPM]":"20.1","Cell RNA - HaCaT [nTPM]":"50.2","Cell RNA - HAP1 [nTPM]":"51.8","Cell RNA - HBEC3-KT [nTPM]":"40.8","Cell RNA - HBF TERT88 [nTPM]":"35.2","Cell RNA - HDLM-2 [nTPM]":"65.9","Cell RNA - HEK 293 [nTPM]":"54.9","Cell RNA - HEL [nTPM]":"42.8","Cell RNA - HeLa [nTPM]":"31.5","Cell RNA - Hep G2 [nTPM]":"47.7","Cell RNA - HHSteC [nTPM]":"21.9","Cell RNA - HL-60 [nTPM]":"46.4","Cell RNA - HMC-1 [nTPM]":"77.3","Cell RNA - HSkMC [nTPM]":"15.9","Cell RNA - hTCEpi [nTPM]":"51.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"51.3","Cell RNA - hTERT-HME1 [nTPM]":"41.5","Cell RNA - hTERT-RPE1 [nTPM]":"32.6","Cell RNA - HUVEC TERT2 [nTPM]":"44.8","Cell RNA - JURKAT [nTPM]":"24.4","Cell RNA - K-562 [nTPM]":"81.4","Cell RNA - Karpas-707 [nTPM]":"42.1","Cell RNA - LHCN-M2 [nTPM]":"34.0","Cell RNA - MCF7 [nTPM]":"56.3","Cell RNA - MOLT-4 [nTPM]":"51.4","Cell RNA - NB-4 [nTPM]":"46.5","Cell RNA - NTERA-2 [nTPM]":"69.8","Cell RNA - OE19 [nTPM]":"117.2","Cell RNA - PC-3 [nTPM]":"49.8","Cell RNA - REH [nTPM]":"64.8","Cell RNA - RH-30 [nTPM]":"37.4","Cell RNA - RPMI-8226 [nTPM]":"76.9","Cell RNA - RPTEC TERT1 [nTPM]":"30.2","Cell RNA - RT4 [nTPM]":"45.7","Cell RNA - SCLC-21H [nTPM]":"37.3","Cell RNA - SH-SY5Y [nTPM]":"108.0","Cell RNA - SiHa [nTPM]":"38.0","Cell RNA - SK-BR-3 [nTPM]":"93.2","Cell RNA - SK-MEL-30 [nTPM]":"38.7","Cell RNA - SuSa [nTPM]":"49.0","Cell RNA - T-47d [nTPM]":"90.1","Cell RNA - THP-1 [nTPM]":"50.4","Cell RNA - TIME [nTPM]":"43.7","Cell RNA - U-138 MG [nTPM]":"34.3","Cell RNA - U-2 OS [nTPM]":"44.9","Cell RNA - U-2197 [nTPM]":"35.3","Cell RNA - U-251 MG [nTPM]":"41.4","Cell RNA - U-266\/70 [nTPM]":"92.7","Cell RNA - U-266\/84 [nTPM]":"79.4","Cell RNA - U-698 [nTPM]":"83.2","Cell RNA - U-87 MG [nTPM]":"21.0","Cell RNA - U-937 [nTPM]":"45.9","Cell RNA - WM-115 [nTPM]":"49.1","Blood RNA - basophil [nTPM]":"9.7","Blood RNA - classical monocyte [nTPM]":"0.7","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"1.9","Blood RNA - memory B-cell [nTPM]":"1.1","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.6","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"0.8","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.2","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.2","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"1.0","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"39.9","Brain RNA - basal ganglia [nTPM]":"47.9","Brain RNA - cerebellum [nTPM]":"34.3","Brain RNA - cerebral cortex [nTPM]":"52.5","Brain RNA - hippocampal formation [nTPM]":"40.8","Brain RNA - hypothalamus [nTPM]":"40.2","Brain RNA - medulla oblongata [nTPM]":"38.1","Brain RNA - midbrain [nTPM]":"38.3","Brain RNA - pons [nTPM]":"37.7","Brain RNA - spinal cord [nTPM]":"37.1","Brain RNA - thalamus [nTPM]":"40.0","Brain RNA - white matter [nTPM]":"39.8","Single Cell Type RNA - Adipocytes [nTPM]":"8.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.3","Single Cell Type RNA - Astrocytes [nTPM]":"9.8","Single Cell Type RNA - B-cells [nTPM]":"8.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.2","Single Cell Type RNA - Bipolar cells [nTPM]":"6.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"8.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.1","Single Cell Type RNA - dendritic cells [nTPM]":"8.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.2","Single Cell Type RNA - Endothelial cells [nTPM]":"9.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.7","Single Cell Type RNA - Erythroid cells [nTPM]":"6.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.1","Single Cell Type RNA - Fibroblasts [nTPM]":"7.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.9","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"13.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"22.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.9","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.8","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"8.4","Single Cell Type RNA - Langerhans cells [nTPM]":"7.2","Single Cell Type RNA - Late spermatids [nTPM]":"4.9","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"8.3","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"15.6","Single Cell Type RNA - Muller glia cells [nTPM]":"7.3","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.1","Single Cell Type RNA - Paneth cells [nTPM]":"6.9","Single Cell Type RNA - Peritubular cells [nTPM]":"9.1","Single Cell Type RNA - Plasma cells [nTPM]":"13.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"25.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.8","Single Cell Type RNA - Spermatocytes [nTPM]":"4.9","Single Cell Type RNA - Spermatogonia [nTPM]":"5.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.2","Single Cell Type RNA - T-cells [nTPM]":"7.7","Single Cell Type RNA - Theca cells [nTPM]":"4.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.0","Single Cell Type RNA - Urothelial cells [nTPM]":"14.3"},{"Gene":"UBR1","Gene synonym":[],"Ensembl":"ENSG00000159459","Gene description":"Ubiquitin protein ligase E3 component n-recognin 1","Uniprot":["Q8IWV7"],"Chromosome":"15","Position":"42942897-43106113","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"48.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"108.9","Inhibitory neurons":"108.8","Oligodendrocyte precursor cells":"102.1","Oligodendrocytes":"127.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038838","HPA038839"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA038838":"AB_10673120","HPA038839":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.1","Tissue RNA - adrenal gland [nTPM]":"7.9","Tissue RNA - amygdala [nTPM]":"12.5","Tissue RNA - appendix [nTPM]":"8.8","Tissue RNA - basal ganglia [nTPM]":"29.4","Tissue RNA - bone marrow [nTPM]":"24.9","Tissue RNA - breast [nTPM]":"9.3","Tissue RNA - cerebellum [nTPM]":"11.7","Tissue RNA - cerebral cortex [nTPM]":"17.4","Tissue RNA - cervix [nTPM]":"9.9","Tissue RNA - choroid plexus [nTPM]":"4.8","Tissue RNA - colon [nTPM]":"8.6","Tissue RNA - duodenum [nTPM]":"7.8","Tissue RNA - endometrium 1 [nTPM]":"10.7","Tissue RNA - epididymis [nTPM]":"7.4","Tissue RNA - esophagus [nTPM]":"5.8","Tissue RNA - fallopian tube [nTPM]":"8.0","Tissue RNA - gallbladder [nTPM]":"8.6","Tissue RNA - heart muscle [nTPM]":"13.7","Tissue RNA - hippocampal formation [nTPM]":"11.6","Tissue RNA - hypothalamus [nTPM]":"31.5","Tissue RNA - kidney [nTPM]":"9.2","Tissue RNA - liver [nTPM]":"7.1","Tissue RNA - lung [nTPM]":"8.6","Tissue RNA - lymph node [nTPM]":"10.9","Tissue RNA - medulla oblongata [nTPM]":"24.2","Tissue RNA - midbrain [nTPM]":"18.3","Tissue RNA - ovary [nTPM]":"7.7","Tissue RNA - pancreas [nTPM]":"9.5","Tissue RNA - parathyroid gland [nTPM]":"14.3","Tissue RNA - pituitary gland [nTPM]":"6.6","Tissue RNA - placenta [nTPM]":"10.5","Tissue RNA - pons [nTPM]":"21.6","Tissue RNA - prostate [nTPM]":"10.0","Tissue RNA - rectum [nTPM]":"8.0","Tissue RNA - retina [nTPM]":"14.3","Tissue RNA - salivary gland [nTPM]":"6.3","Tissue RNA - seminal vesicle [nTPM]":"10.5","Tissue RNA - skeletal muscle [nTPM]":"12.0","Tissue RNA - skin 1 [nTPM]":"5.6","Tissue RNA - small intestine [nTPM]":"7.8","Tissue RNA - smooth muscle [nTPM]":"9.6","Tissue RNA - spinal cord [nTPM]":"8.5","Tissue RNA - spleen [nTPM]":"9.5","Tissue RNA - stomach 1 [nTPM]":"7.2","Tissue RNA - testis [nTPM]":"10.1","Tissue RNA - thalamus [nTPM]":"21.2","Tissue RNA - thymus [nTPM]":"13.3","Tissue RNA - thyroid gland [nTPM]":"12.6","Tissue RNA - tongue [nTPM]":"14.0","Tissue RNA - tonsil [nTPM]":"8.7","Tissue RNA - urinary bladder [nTPM]":"9.1","Tissue RNA - vagina [nTPM]":"5.8","Tissue RNA - white matter [nTPM]":"48.6","Cell RNA - A-431 [nTPM]":"7.4","Cell RNA - A549 [nTPM]":"10.2","Cell RNA - AF22 [nTPM]":"11.6","Cell RNA - AN3-CA [nTPM]":"9.6","Cell RNA - ASC diff [nTPM]":"17.1","Cell RNA - ASC TERT1 [nTPM]":"14.7","Cell RNA - BEWO [nTPM]":"10.7","Cell RNA - BJ [nTPM]":"17.6","Cell RNA - BJ hTERT+ [nTPM]":"19.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.2","Cell RNA - CACO-2 [nTPM]":"13.3","Cell RNA - CAPAN-2 [nTPM]":"5.5","Cell RNA - Daudi [nTPM]":"8.6","Cell RNA - EFO-21 [nTPM]":"10.1","Cell RNA - fHDF\/TERT166 [nTPM]":"18.4","Cell RNA - GAMG [nTPM]":"18.9","Cell RNA - HaCaT [nTPM]":"12.4","Cell RNA - HAP1 [nTPM]":"17.1","Cell RNA - HBEC3-KT [nTPM]":"15.5","Cell RNA - HBF TERT88 [nTPM]":"18.1","Cell RNA - HDLM-2 [nTPM]":"18.0","Cell RNA - HEK 293 [nTPM]":"8.4","Cell RNA - HEL [nTPM]":"33.1","Cell RNA - HeLa [nTPM]":"20.4","Cell RNA - Hep G2 [nTPM]":"6.3","Cell RNA - HHSteC [nTPM]":"12.3","Cell RNA - HL-60 [nTPM]":"23.0","Cell RNA - HMC-1 [nTPM]":"14.4","Cell RNA - HSkMC [nTPM]":"15.3","Cell RNA - hTCEpi [nTPM]":"8.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.8","Cell RNA - hTERT-HME1 [nTPM]":"14.8","Cell RNA - hTERT-RPE1 [nTPM]":"14.6","Cell RNA - HUVEC TERT2 [nTPM]":"17.0","Cell RNA - JURKAT [nTPM]":"16.7","Cell RNA - K-562 [nTPM]":"19.6","Cell RNA - Karpas-707 [nTPM]":"12.3","Cell RNA - LHCN-M2 [nTPM]":"18.7","Cell RNA - MCF7 [nTPM]":"4.5","Cell RNA - MOLT-4 [nTPM]":"12.7","Cell RNA - NB-4 [nTPM]":"6.8","Cell RNA - NTERA-2 [nTPM]":"6.5","Cell RNA - OE19 [nTPM]":"18.9","Cell RNA - PC-3 [nTPM]":"10.6","Cell RNA - REH [nTPM]":"16.4","Cell RNA - RH-30 [nTPM]":"15.7","Cell RNA - RPMI-8226 [nTPM]":"6.4","Cell RNA - RPTEC TERT1 [nTPM]":"14.9","Cell RNA - RT4 [nTPM]":"16.6","Cell RNA - SCLC-21H [nTPM]":"12.0","Cell RNA - SH-SY5Y [nTPM]":"10.3","Cell RNA - SiHa [nTPM]":"22.7","Cell RNA - SK-BR-3 [nTPM]":"12.0","Cell RNA - SK-MEL-30 [nTPM]":"7.7","Cell RNA - SuSa [nTPM]":"13.1","Cell RNA - T-47d [nTPM]":"10.9","Cell RNA - THP-1 [nTPM]":"12.2","Cell RNA - TIME [nTPM]":"24.3","Cell RNA - U-138 MG [nTPM]":"17.9","Cell RNA - U-2 OS [nTPM]":"11.1","Cell RNA - U-2197 [nTPM]":"16.7","Cell RNA - U-251 MG [nTPM]":"18.0","Cell RNA - U-266\/70 [nTPM]":"14.6","Cell RNA - U-266\/84 [nTPM]":"26.4","Cell RNA - U-698 [nTPM]":"23.6","Cell RNA - U-87 MG [nTPM]":"12.2","Cell RNA - U-937 [nTPM]":"14.6","Cell RNA - WM-115 [nTPM]":"16.6","Blood RNA - basophil [nTPM]":"3.7","Blood RNA - classical monocyte [nTPM]":"1.5","Blood RNA - eosinophil [nTPM]":"2.5","Blood RNA - gdT-cell [nTPM]":"2.4","Blood RNA - intermediate monocyte [nTPM]":"1.8","Blood RNA - MAIT T-cell [nTPM]":"2.9","Blood RNA - memory B-cell [nTPM]":"1.9","Blood RNA - memory CD4 T-cell [nTPM]":"2.6","Blood RNA - memory CD8 T-cell [nTPM]":"2.9","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"2.3","Blood RNA - naive CD4 T-cell [nTPM]":"2.6","Blood RNA - naive CD8 T-cell [nTPM]":"3.2","Blood RNA - neutrophil [nTPM]":"2.9","Blood RNA - NK-cell [nTPM]":"3.2","Blood RNA - non-classical monocyte [nTPM]":"1.7","Blood RNA - plasmacytoid DC [nTPM]":"2.2","Blood RNA - T-reg [nTPM]":"1.9","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"12.5","Brain RNA - basal ganglia [nTPM]":"29.4","Brain RNA - cerebellum [nTPM]":"11.7","Brain RNA - cerebral cortex [nTPM]":"17.4","Brain RNA - hippocampal formation [nTPM]":"11.6","Brain RNA - hypothalamus [nTPM]":"31.5","Brain RNA - medulla oblongata [nTPM]":"24.2","Brain RNA - midbrain [nTPM]":"18.3","Brain RNA - pons [nTPM]":"21.6","Brain RNA - spinal cord [nTPM]":"8.5","Brain RNA - thalamus [nTPM]":"21.2","Brain RNA - white matter [nTPM]":"48.6","Single Cell Type RNA - Adipocytes [nTPM]":"46.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"30.7","Single Cell Type RNA - Astrocytes [nTPM]":"73.1","Single Cell Type RNA - B-cells [nTPM]":"28.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Bipolar cells [nTPM]":"27.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"28.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"19.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.7","Single Cell Type RNA - dendritic cells [nTPM]":"35.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"10.8","Single Cell Type RNA - Early spermatids [nTPM]":"16.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"27.4","Single Cell Type RNA - Endothelial cells [nTPM]":"24.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.4","Single Cell Type RNA - Erythroid cells [nTPM]":"23.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"108.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.7","Single Cell Type RNA - Fibroblasts [nTPM]":"25.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.2","Single Cell Type RNA - granulocytes [nTPM]":"28.5","Single Cell Type RNA - Granulosa cells [nTPM]":"22.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.2","Single Cell Type RNA - Hepatocytes [nTPM]":"9.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.1","Single Cell Type RNA - Horizontal cells [nTPM]":"32.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"108.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.9","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"16.4","Single Cell Type RNA - Langerhans cells [nTPM]":"10.6","Single Cell Type RNA - Late spermatids [nTPM]":"16.9","Single Cell Type RNA - Leydig cells [nTPM]":"16.1","Single Cell Type RNA - Macrophages [nTPM]":"17.1","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"73.1","Single Cell Type RNA - monocytes [nTPM]":"15.6","Single Cell Type RNA - Muller glia cells [nTPM]":"13.5","Single Cell Type RNA - NK-cells [nTPM]":"23.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"102.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"127.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.3","Single Cell Type RNA - Paneth cells [nTPM]":"8.2","Single Cell Type RNA - Peritubular cells [nTPM]":"20.7","Single Cell Type RNA - Plasma cells [nTPM]":"33.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"38.8","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"34.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"36.5","Single Cell Type RNA - Spermatocytes [nTPM]":"27.0","Single Cell Type RNA - Spermatogonia [nTPM]":"17.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"36.9","Single Cell Type RNA - T-cells [nTPM]":"31.4","Single Cell Type RNA - Theca cells [nTPM]":"16.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.6","Single Cell Type RNA - Urothelial cells [nTPM]":"9.8"},{"Gene":"UCHL1","Gene synonym":["PARK5","PGP9.5","Uch-L1"],"Ensembl":"ENSG00000154277","Gene description":"Ubiquitin C-terminal hydrolase L1","Uniprot":["P09936"],"Chromosome":"4","Position":"41256413-41268455","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"692.7","pituitary gland":"285.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"115.8","Distal tubular cells":"258.2","Excitatory neurons":"147.1","Horizontal cells":"146.4","Inhibitory neurons":"118.4","Spermatogonia":"88.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"129.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"1142.2","SCLC-21H":"1160.6","U-251 MG":"1162.6","U-266\/84":"1138.4","U-87 MG":"1209.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002580","HPA005993","CAB079024"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"500000","Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB002580":"AB_563981","CAB079024":null,"HPA005993":"AB_1858560"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.08e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.77e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.93e-4"},"Tissue RNA - adipose tissue [nTPM]":"30.1","Tissue RNA - adrenal gland [nTPM]":"104.4","Tissue RNA - amygdala [nTPM]":"211.4","Tissue RNA - appendix [nTPM]":"19.2","Tissue RNA - basal ganglia [nTPM]":"188.8","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"13.6","Tissue RNA - cerebellum [nTPM]":"83.4","Tissue RNA - cerebral cortex [nTPM]":"342.7","Tissue RNA - cervix [nTPM]":"18.9","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"49.0","Tissue RNA - duodenum [nTPM]":"9.0","Tissue RNA - endometrium 1 [nTPM]":"13.2","Tissue RNA - epididymis [nTPM]":"3.3","Tissue RNA - esophagus [nTPM]":"3.3","Tissue RNA - fallopian tube [nTPM]":"9.7","Tissue RNA - gallbladder [nTPM]":"12.3","Tissue RNA - heart muscle [nTPM]":"26.9","Tissue RNA - hippocampal formation [nTPM]":"229.7","Tissue RNA - hypothalamus [nTPM]":"692.7","Tissue RNA - kidney [nTPM]":"62.7","Tissue RNA - liver [nTPM]":"1.6","Tissue RNA - lung [nTPM]":"8.2","Tissue RNA - lymph node [nTPM]":"12.9","Tissue RNA - medulla oblongata [nTPM]":"255.7","Tissue RNA - midbrain [nTPM]":"205.2","Tissue RNA - ovary [nTPM]":"35.6","Tissue RNA - pancreas [nTPM]":"11.6","Tissue RNA - parathyroid gland [nTPM]":"0.6","Tissue RNA - pituitary gland [nTPM]":"285.4","Tissue RNA - placenta [nTPM]":"2.5","Tissue RNA - pons [nTPM]":"446.7","Tissue RNA - prostate [nTPM]":"12.3","Tissue RNA - rectum [nTPM]":"6.9","Tissue RNA - retina [nTPM]":"38.3","Tissue RNA - salivary gland [nTPM]":"3.7","Tissue RNA - seminal vesicle [nTPM]":"5.8","Tissue RNA - skeletal muscle [nTPM]":"27.5","Tissue RNA - skin 1 [nTPM]":"4.7","Tissue RNA - small intestine [nTPM]":"18.9","Tissue RNA - smooth muscle [nTPM]":"9.2","Tissue RNA - spinal cord [nTPM]":"122.2","Tissue RNA - spleen [nTPM]":"2.7","Tissue RNA - stomach 1 [nTPM]":"14.5","Tissue RNA - testis [nTPM]":"16.5","Tissue RNA - thalamus [nTPM]":"150.3","Tissue RNA - thymus [nTPM]":"4.1","Tissue RNA - thyroid gland [nTPM]":"9.8","Tissue RNA - tongue [nTPM]":"7.7","Tissue RNA - tonsil [nTPM]":"7.3","Tissue RNA - urinary bladder [nTPM]":"31.7","Tissue RNA - vagina [nTPM]":"29.1","Tissue RNA - white matter [nTPM]":"231.2","Cell RNA - A-431 [nTPM]":"3.3","Cell RNA - A549 [nTPM]":"712.8","Cell RNA - AF22 [nTPM]":"146.8","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"18.9","Cell RNA - ASC TERT1 [nTPM]":"19.7","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"681.4","Cell RNA - BJ hTERT+ [nTPM]":"352.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"236.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"243.4","Cell RNA - CACO-2 [nTPM]":"149.0","Cell RNA - CAPAN-2 [nTPM]":"0.9","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1142.2","Cell RNA - fHDF\/TERT166 [nTPM]":"384.4","Cell RNA - GAMG [nTPM]":"356.7","Cell RNA - HaCaT [nTPM]":"1.1","Cell RNA - HAP1 [nTPM]":"262.8","Cell RNA - HBEC3-KT [nTPM]":"0.6","Cell RNA - HBF TERT88 [nTPM]":"116.4","Cell RNA - HDLM-2 [nTPM]":"1.5","Cell RNA - HEK 293 [nTPM]":"97.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"6.9","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"529.3","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"1.2","Cell RNA - HSkMC [nTPM]":"127.4","Cell RNA - hTCEpi [nTPM]":"3.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"197.9","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"413.7","Cell RNA - HUVEC TERT2 [nTPM]":"2.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"2.3","Cell RNA - LHCN-M2 [nTPM]":"122.6","Cell RNA - MCF7 [nTPM]":"0.6","Cell RNA - MOLT-4 [nTPM]":"1.0","Cell RNA - NB-4 [nTPM]":"12.3","Cell RNA - NTERA-2 [nTPM]":"435.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"714.1","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"297.2","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"386.3","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"1160.6","Cell RNA - SH-SY5Y [nTPM]":"765.7","Cell RNA - SiHa [nTPM]":"5.1","Cell RNA - SK-BR-3 [nTPM]":"2.8","Cell RNA - SK-MEL-30 [nTPM]":"1.8","Cell RNA - SuSa [nTPM]":"165.4","Cell RNA - T-47d [nTPM]":"0.8","Cell RNA - THP-1 [nTPM]":"5.0","Cell RNA - TIME [nTPM]":"3.3","Cell RNA - U-138 MG [nTPM]":"16.8","Cell RNA - U-2 OS [nTPM]":"5.2","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"1162.6","Cell RNA - U-266\/70 [nTPM]":"583.1","Cell RNA - U-266\/84 [nTPM]":"1138.4","Cell RNA - U-698 [nTPM]":"3.1","Cell RNA - U-87 MG [nTPM]":"1209.3","Cell RNA - U-937 [nTPM]":"1.1","Cell RNA - WM-115 [nTPM]":"1.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"211.4","Brain RNA - basal ganglia [nTPM]":"188.8","Brain RNA - cerebellum [nTPM]":"83.4","Brain RNA - cerebral cortex [nTPM]":"342.7","Brain RNA - hippocampal formation [nTPM]":"229.7","Brain RNA - hypothalamus [nTPM]":"692.7","Brain RNA - medulla oblongata [nTPM]":"255.7","Brain RNA - midbrain [nTPM]":"205.2","Brain RNA - pons [nTPM]":"446.7","Brain RNA - spinal cord [nTPM]":"122.2","Brain RNA - thalamus [nTPM]":"150.3","Brain RNA - white matter [nTPM]":"231.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.1","Single Cell Type RNA - Astrocytes [nTPM]":"29.0","Single Cell Type RNA - B-cells [nTPM]":"2.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"25.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"115.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"258.2","Single Cell Type RNA - Ductal cells [nTPM]":"4.3","Single Cell Type RNA - Early spermatids [nTPM]":"3.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.8","Single Cell Type RNA - Endothelial cells [nTPM]":"3.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"147.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.8","Single Cell Type RNA - Fibroblasts [nTPM]":"35.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"46.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.9","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.7","Single Cell Type RNA - Horizontal cells [nTPM]":"146.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"118.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"3.4","Single Cell Type RNA - Late spermatids [nTPM]":"6.0","Single Cell Type RNA - Leydig cells [nTPM]":"37.0","Single Cell Type RNA - Macrophages [nTPM]":"2.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"35.6","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"21.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"55.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"54.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"17.3","Single Cell Type RNA - Plasma cells [nTPM]":"9.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"61.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"35.7","Single Cell Type RNA - Spermatocytes [nTPM]":"10.4","Single Cell Type RNA - Spermatogonia [nTPM]":"88.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - T-cells [nTPM]":"1.3","Single Cell Type RNA - Theca cells [nTPM]":"20.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"1.0"},{"Gene":"UCP3","Gene synonym":["SLC25A9"],"Ensembl":"ENSG00000175564","Gene description":"Uncoupling protein 3","Uniprot":["P55916"],"Chromosome":"11","Position":"74000277-74009085","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Diabetes mellitus","Disease variant","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"80","RNA tissue specific nTPM":{"skeletal muscle":"393.2","tongue":"263.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"15.4","Late spermatids":"14.0","NK-cells":"6.2","Skeletal myocytes":"6.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"HDLM-2":"15.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010771","HPA072225"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 37: Myocytes - Muscle contraction","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB010771":"AB_261839","HPA072225":"AB_2686498"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-4"},"Tissue RNA - adipose tissue [nTPM]":"1.2","Tissue RNA - adrenal gland [nTPM]":"1.7","Tissue RNA - amygdala [nTPM]":"2.5","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"2.6","Tissue RNA - bone marrow [nTPM]":"2.2","Tissue RNA - breast [nTPM]":"1.3","Tissue RNA - cerebellum [nTPM]":"3.9","Tissue RNA - cerebral cortex [nTPM]":"3.0","Tissue RNA - cervix [nTPM]":"1.4","Tissue RNA - choroid plexus [nTPM]":"2.3","Tissue RNA - colon [nTPM]":"1.7","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"1.4","Tissue RNA - epididymis [nTPM]":"2.0","Tissue RNA - esophagus [nTPM]":"2.9","Tissue RNA - fallopian tube [nTPM]":"1.5","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"2.4","Tissue RNA - hippocampal formation [nTPM]":"2.7","Tissue RNA - hypothalamus [nTPM]":"2.1","Tissue RNA - kidney [nTPM]":"1.7","Tissue RNA - liver [nTPM]":"1.3","Tissue RNA - lung [nTPM]":"1.4","Tissue RNA - lymph node [nTPM]":"1.3","Tissue RNA - medulla oblongata [nTPM]":"2.4","Tissue RNA - midbrain [nTPM]":"2.1","Tissue RNA - ovary [nTPM]":"1.1","Tissue RNA - pancreas [nTPM]":"1.1","Tissue RNA - parathyroid gland [nTPM]":"0.9","Tissue RNA - pituitary gland [nTPM]":"2.7","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"2.3","Tissue RNA - prostate [nTPM]":"1.8","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"4.0","Tissue RNA - salivary gland [nTPM]":"3.7","Tissue RNA - seminal vesicle [nTPM]":"0.7","Tissue RNA - skeletal muscle [nTPM]":"393.2","Tissue RNA - skin 1 [nTPM]":"1.4","Tissue RNA - small intestine [nTPM]":"1.7","Tissue RNA - smooth muscle [nTPM]":"0.8","Tissue RNA - spinal cord [nTPM]":"1.8","Tissue RNA - spleen [nTPM]":"3.1","Tissue RNA - stomach 1 [nTPM]":"1.2","Tissue RNA - testis [nTPM]":"3.9","Tissue RNA - thalamus [nTPM]":"2.4","Tissue RNA - thymus [nTPM]":"1.6","Tissue RNA - thyroid gland [nTPM]":"2.6","Tissue RNA - tongue [nTPM]":"263.1","Tissue RNA - tonsil [nTPM]":"0.7","Tissue RNA - urinary bladder [nTPM]":"1.4","Tissue RNA - vagina [nTPM]":"0.9","Tissue RNA - white matter [nTPM]":"2.8","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"1.8","Cell RNA - AF22 [nTPM]":"1.7","Cell RNA - AN3-CA [nTPM]":"1.5","Cell RNA - ASC diff [nTPM]":"0.7","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.5","Cell RNA - BJ hTERT+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"0.9","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.3","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"1.9","Cell RNA - HAP1 [nTPM]":"0.7","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"0.7","Cell RNA - HDLM-2 [nTPM]":"15.8","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"2.4","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.5","Cell RNA - HL-60 [nTPM]":"1.1","Cell RNA - HMC-1 [nTPM]":"1.4","Cell RNA - HSkMC [nTPM]":"0.4","Cell RNA - hTCEpi [nTPM]":"1.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.1","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.5","Cell RNA - JURKAT [nTPM]":"0.9","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"1.2","Cell RNA - LHCN-M2 [nTPM]":"0.6","Cell RNA - MCF7 [nTPM]":"1.0","Cell RNA - MOLT-4 [nTPM]":"0.7","Cell RNA - NB-4 [nTPM]":"1.4","Cell RNA - NTERA-2 [nTPM]":"0.9","Cell RNA - OE19 [nTPM]":"1.4","Cell RNA - PC-3 [nTPM]":"1.1","Cell RNA - REH [nTPM]":"1.4","Cell RNA - RH-30 [nTPM]":"3.6","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.9","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.9","Cell RNA - SH-SY5Y [nTPM]":"1.0","Cell RNA - SiHa [nTPM]":"0.4","Cell RNA - SK-BR-3 [nTPM]":"0.7","Cell RNA - SK-MEL-30 [nTPM]":"0.6","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"1.0","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"1.1","Cell RNA - U-2197 [nTPM]":"0.6","Cell RNA - U-251 MG [nTPM]":"1.1","Cell RNA - U-266\/70 [nTPM]":"1.4","Cell RNA - U-266\/84 [nTPM]":"1.5","Cell RNA - U-698 [nTPM]":"0.7","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"1.0","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.5","Brain RNA - basal ganglia [nTPM]":"2.6","Brain RNA - cerebellum [nTPM]":"3.9","Brain RNA - cerebral cortex [nTPM]":"3.0","Brain RNA - hippocampal formation [nTPM]":"2.7","Brain RNA - hypothalamus [nTPM]":"2.1","Brain RNA - medulla oblongata [nTPM]":"2.4","Brain RNA - midbrain [nTPM]":"2.1","Brain RNA - pons [nTPM]":"2.3","Brain RNA - spinal cord [nTPM]":"1.8","Brain RNA - thalamus [nTPM]":"2.4","Brain RNA - white matter [nTPM]":"2.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"0.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"2.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"2.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"15.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.5","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"14.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"1.5","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"UFSP2","Gene synonym":["C4orf20","FLJ11200"],"Ensembl":"ENSG00000109775","Gene description":"UFM1 specific peptidase 2","Uniprot":["Q9NUQ7"],"Chromosome":"4","Position":"185399537-185425979","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"190.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039985","HPA043298"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA039985":"AB_10794206","HPA043298":"AB_10795037"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.07e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-3"},"Tissue RNA - adipose tissue [nTPM]":"21.2","Tissue RNA - adrenal gland [nTPM]":"24.9","Tissue RNA - amygdala [nTPM]":"19.9","Tissue RNA - appendix [nTPM]":"9.5","Tissue RNA - basal ganglia [nTPM]":"21.7","Tissue RNA - bone marrow [nTPM]":"5.7","Tissue RNA - breast [nTPM]":"24.3","Tissue RNA - cerebellum [nTPM]":"25.2","Tissue RNA - cerebral cortex [nTPM]":"24.1","Tissue RNA - cervix [nTPM]":"21.6","Tissue RNA - choroid plexus [nTPM]":"29.6","Tissue RNA - colon [nTPM]":"19.5","Tissue RNA - duodenum [nTPM]":"13.0","Tissue RNA - endometrium 1 [nTPM]":"19.9","Tissue RNA - epididymis [nTPM]":"28.1","Tissue RNA - esophagus [nTPM]":"25.8","Tissue RNA - fallopian tube [nTPM]":"17.7","Tissue RNA - gallbladder [nTPM]":"15.6","Tissue RNA - heart muscle [nTPM]":"32.1","Tissue RNA - hippocampal formation [nTPM]":"20.4","Tissue RNA - hypothalamus [nTPM]":"21.9","Tissue RNA - kidney [nTPM]":"37.3","Tissue RNA - liver [nTPM]":"24.1","Tissue RNA - lung [nTPM]":"17.1","Tissue RNA - lymph node [nTPM]":"11.9","Tissue RNA - medulla oblongata [nTPM]":"20.4","Tissue RNA - midbrain [nTPM]":"20.2","Tissue RNA - ovary [nTPM]":"31.4","Tissue RNA - pancreas [nTPM]":"19.7","Tissue RNA - parathyroid gland [nTPM]":"23.8","Tissue RNA - pituitary gland [nTPM]":"10.0","Tissue RNA - placenta [nTPM]":"14.0","Tissue RNA - pons [nTPM]":"20.9","Tissue RNA - prostate [nTPM]":"19.8","Tissue RNA - rectum [nTPM]":"15.3","Tissue RNA - retina [nTPM]":"56.4","Tissue RNA - salivary gland [nTPM]":"20.3","Tissue RNA - seminal vesicle [nTPM]":"19.2","Tissue RNA - skeletal muscle [nTPM]":"48.5","Tissue RNA - skin 1 [nTPM]":"21.6","Tissue RNA - small intestine [nTPM]":"12.0","Tissue RNA - smooth muscle [nTPM]":"20.2","Tissue RNA - spinal cord [nTPM]":"20.7","Tissue RNA - spleen [nTPM]":"14.5","Tissue RNA - stomach 1 [nTPM]":"17.5","Tissue RNA - testis [nTPM]":"21.0","Tissue RNA - thalamus [nTPM]":"21.3","Tissue RNA - thymus [nTPM]":"14.3","Tissue RNA - thyroid gland [nTPM]":"25.9","Tissue RNA - tongue [nTPM]":"40.6","Tissue RNA - tonsil [nTPM]":"16.1","Tissue RNA - urinary bladder [nTPM]":"16.2","Tissue RNA - vagina [nTPM]":"10.1","Tissue RNA - white matter [nTPM]":"25.3","Cell RNA - A-431 [nTPM]":"17.5","Cell RNA - A549 [nTPM]":"11.9","Cell RNA - AF22 [nTPM]":"28.8","Cell RNA - AN3-CA [nTPM]":"24.3","Cell RNA - ASC diff [nTPM]":"25.8","Cell RNA - ASC TERT1 [nTPM]":"25.6","Cell RNA - BEWO [nTPM]":"15.3","Cell RNA - BJ [nTPM]":"20.3","Cell RNA - BJ hTERT+ [nTPM]":"20.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.3","Cell RNA - CACO-2 [nTPM]":"18.4","Cell RNA - CAPAN-2 [nTPM]":"23.2","Cell RNA - Daudi [nTPM]":"17.9","Cell RNA - EFO-21 [nTPM]":"9.0","Cell RNA - fHDF\/TERT166 [nTPM]":"19.7","Cell RNA - GAMG [nTPM]":"14.7","Cell RNA - HaCaT [nTPM]":"16.1","Cell RNA - HAP1 [nTPM]":"20.4","Cell RNA - HBEC3-KT [nTPM]":"32.2","Cell RNA - HBF TERT88 [nTPM]":"17.4","Cell RNA - HDLM-2 [nTPM]":"21.8","Cell RNA - HEK 293 [nTPM]":"12.4","Cell RNA - HEL [nTPM]":"11.8","Cell RNA - HeLa [nTPM]":"13.0","Cell RNA - Hep G2 [nTPM]":"23.3","Cell RNA - HHSteC [nTPM]":"30.2","Cell RNA - HL-60 [nTPM]":"15.3","Cell RNA - HMC-1 [nTPM]":"12.3","Cell RNA - HSkMC [nTPM]":"14.7","Cell RNA - hTCEpi [nTPM]":"26.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.5","Cell RNA - hTERT-HME1 [nTPM]":"16.7","Cell RNA - hTERT-RPE1 [nTPM]":"26.7","Cell RNA - HUVEC TERT2 [nTPM]":"35.7","Cell RNA - JURKAT [nTPM]":"21.9","Cell RNA - K-562 [nTPM]":"24.8","Cell RNA - Karpas-707 [nTPM]":"34.3","Cell RNA - LHCN-M2 [nTPM]":"28.2","Cell RNA - MCF7 [nTPM]":"16.3","Cell RNA - MOLT-4 [nTPM]":"22.0","Cell RNA - NB-4 [nTPM]":"16.4","Cell RNA - NTERA-2 [nTPM]":"8.7","Cell RNA - OE19 [nTPM]":"11.8","Cell RNA - PC-3 [nTPM]":"16.7","Cell RNA - REH [nTPM]":"20.2","Cell RNA - RH-30 [nTPM]":"11.5","Cell RNA - RPMI-8226 [nTPM]":"20.4","Cell RNA - RPTEC TERT1 [nTPM]":"31.9","Cell RNA - RT4 [nTPM]":"11.4","Cell RNA - SCLC-21H [nTPM]":"18.6","Cell RNA - SH-SY5Y [nTPM]":"14.8","Cell RNA - SiHa [nTPM]":"11.3","Cell RNA - SK-BR-3 [nTPM]":"25.6","Cell RNA - SK-MEL-30 [nTPM]":"23.1","Cell RNA - SuSa [nTPM]":"17.6","Cell RNA - T-47d [nTPM]":"15.4","Cell RNA - THP-1 [nTPM]":"13.6","Cell RNA - TIME [nTPM]":"27.3","Cell RNA - U-138 MG [nTPM]":"9.5","Cell RNA - U-2 OS [nTPM]":"16.8","Cell RNA - U-2197 [nTPM]":"7.5","Cell RNA - U-251 MG [nTPM]":"17.2","Cell RNA - U-266\/70 [nTPM]":"34.6","Cell RNA - U-266\/84 [nTPM]":"14.8","Cell RNA - U-698 [nTPM]":"9.5","Cell RNA - U-87 MG [nTPM]":"30.5","Cell RNA - U-937 [nTPM]":"11.0","Cell RNA - WM-115 [nTPM]":"25.3","Blood RNA - basophil [nTPM]":"10.8","Blood RNA - classical monocyte [nTPM]":"12.3","Blood RNA - eosinophil [nTPM]":"7.6","Blood RNA - gdT-cell [nTPM]":"21.2","Blood RNA - intermediate monocyte [nTPM]":"10.4","Blood RNA - MAIT T-cell [nTPM]":"25.7","Blood RNA - memory B-cell [nTPM]":"22.0","Blood RNA - memory CD4 T-cell [nTPM]":"21.7","Blood RNA - memory CD8 T-cell [nTPM]":"24.1","Blood RNA - myeloid DC [nTPM]":"14.1","Blood RNA - naive B-cell [nTPM]":"15.4","Blood RNA - naive CD4 T-cell [nTPM]":"23.2","Blood RNA - naive CD8 T-cell [nTPM]":"22.9","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"21.5","Blood RNA - non-classical monocyte [nTPM]":"11.1","Blood RNA - plasmacytoid DC [nTPM]":"19.9","Blood RNA - T-reg [nTPM]":"20.6","Blood RNA - total PBMC [nTPM]":"12.5","Brain RNA - amygdala [nTPM]":"19.9","Brain RNA - basal ganglia [nTPM]":"21.7","Brain RNA - cerebellum [nTPM]":"25.2","Brain RNA - cerebral cortex [nTPM]":"24.1","Brain RNA - hippocampal formation [nTPM]":"20.4","Brain RNA - hypothalamus [nTPM]":"21.9","Brain RNA - medulla oblongata [nTPM]":"20.4","Brain RNA - midbrain [nTPM]":"20.2","Brain RNA - pons [nTPM]":"20.9","Brain RNA - spinal cord [nTPM]":"20.7","Brain RNA - thalamus [nTPM]":"21.3","Brain RNA - white matter [nTPM]":"25.3","Single Cell Type RNA - Adipocytes [nTPM]":"33.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.9","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"30.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"22.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"28.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"35.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"33.0","Single Cell Type RNA - Bipolar cells [nTPM]":"47.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"20.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"25.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"27.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"31.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"66.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"26.0","Single Cell Type RNA - dendritic cells [nTPM]":"23.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"111.6","Single Cell Type RNA - Ductal cells [nTPM]":"28.3","Single Cell Type RNA - Early spermatids [nTPM]":"190.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"28.9","Single Cell Type RNA - Endothelial cells [nTPM]":"24.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.3","Single Cell Type RNA - Erythroid cells [nTPM]":"24.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"33.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"29.7","Single Cell Type RNA - Fibroblasts [nTPM]":"34.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.2","Single Cell Type RNA - granulocytes [nTPM]":"29.7","Single Cell Type RNA - Granulosa cells [nTPM]":"21.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.8","Single Cell Type RNA - Hepatocytes [nTPM]":"17.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"27.2","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.6","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"22.1","Single Cell Type RNA - Langerhans cells [nTPM]":"18.8","Single Cell Type RNA - Late spermatids [nTPM]":"52.9","Single Cell Type RNA - Leydig cells [nTPM]":"35.4","Single Cell Type RNA - Macrophages [nTPM]":"18.5","Single Cell Type RNA - Melanocytes [nTPM]":"35.6","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"17.3","Single Cell Type RNA - Muller glia cells [nTPM]":"71.8","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"23.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"33.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.7","Single Cell Type RNA - Paneth cells [nTPM]":"14.6","Single Cell Type RNA - Peritubular cells [nTPM]":"42.2","Single Cell Type RNA - Plasma cells [nTPM]":"53.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"100.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"87.9","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"31.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"38.9","Single Cell Type RNA - Spermatocytes [nTPM]":"89.3","Single Cell Type RNA - Spermatogonia [nTPM]":"56.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"41.9","Single Cell Type RNA - T-cells [nTPM]":"27.1","Single Cell Type RNA - Theca cells [nTPM]":"35.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.8","Single Cell Type RNA - Urothelial cells [nTPM]":"19.6"},{"Gene":"UGDH","Gene synonym":[],"Ensembl":"ENSG00000109814","Gene description":"UDP-glucose 6-dehydrogenase","Uniprot":["O60701"],"Chromosome":"4","Position":"39498755-39528311","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism"],"Molecular function":["Allosteric enzyme","Oxidoreductase"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"137.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Exocrine glandular cells":"345.5","Hepatocytes":"231.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"509.6","Hep G2":"595.9","U-2197":"375.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034444","HPA036656","HPA036657"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1300000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 1: Pancreatic cells - Digestion","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB034444":"AB_2019602","HPA036656":"AB_10671706","HPA036657":"AB_10672360"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.51e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Tissue RNA - adipose tissue [nTPM]":"48.5","Tissue RNA - adrenal gland [nTPM]":"27.8","Tissue RNA - amygdala [nTPM]":"6.2","Tissue RNA - appendix [nTPM]":"29.5","Tissue RNA - basal ganglia [nTPM]":"7.3","Tissue RNA - bone marrow [nTPM]":"2.4","Tissue RNA - breast [nTPM]":"32.0","Tissue RNA - cerebellum [nTPM]":"9.4","Tissue RNA - cerebral cortex [nTPM]":"9.2","Tissue RNA - cervix [nTPM]":"31.5","Tissue RNA - choroid plexus [nTPM]":"18.1","Tissue RNA - colon [nTPM]":"96.5","Tissue RNA - duodenum [nTPM]":"45.3","Tissue RNA - endometrium 1 [nTPM]":"29.1","Tissue RNA - epididymis [nTPM]":"10.6","Tissue RNA - esophagus [nTPM]":"34.1","Tissue RNA - fallopian tube [nTPM]":"29.6","Tissue RNA - gallbladder [nTPM]":"40.5","Tissue RNA - heart muscle [nTPM]":"16.0","Tissue RNA - hippocampal formation [nTPM]":"5.9","Tissue RNA - hypothalamus [nTPM]":"8.3","Tissue RNA - kidney [nTPM]":"37.5","Tissue RNA - liver [nTPM]":"137.7","Tissue RNA - lung [nTPM]":"19.0","Tissue RNA - lymph node [nTPM]":"13.3","Tissue RNA - medulla oblongata [nTPM]":"7.4","Tissue RNA - midbrain [nTPM]":"7.7","Tissue RNA - ovary [nTPM]":"30.0","Tissue RNA - pancreas [nTPM]":"33.7","Tissue RNA - parathyroid gland [nTPM]":"23.1","Tissue RNA - pituitary gland [nTPM]":"7.8","Tissue RNA - placenta [nTPM]":"38.4","Tissue RNA - pons [nTPM]":"8.0","Tissue RNA - prostate [nTPM]":"35.6","Tissue RNA - rectum [nTPM]":"73.3","Tissue RNA - retina [nTPM]":"14.3","Tissue RNA - salivary gland [nTPM]":"16.8","Tissue RNA - seminal vesicle [nTPM]":"14.0","Tissue RNA - skeletal muscle [nTPM]":"6.7","Tissue RNA - skin 1 [nTPM]":"9.9","Tissue RNA - small intestine [nTPM]":"41.1","Tissue RNA - smooth muscle [nTPM]":"23.5","Tissue RNA - spinal cord [nTPM]":"7.6","Tissue RNA - spleen [nTPM]":"11.5","Tissue RNA - stomach 1 [nTPM]":"47.4","Tissue RNA - testis [nTPM]":"6.8","Tissue RNA - thalamus [nTPM]":"8.4","Tissue RNA - thymus [nTPM]":"10.3","Tissue RNA - thyroid gland [nTPM]":"27.8","Tissue RNA - tongue [nTPM]":"9.5","Tissue RNA - tonsil [nTPM]":"14.5","Tissue RNA - urinary bladder [nTPM]":"54.4","Tissue RNA - vagina [nTPM]":"17.1","Tissue RNA - white matter [nTPM]":"9.7","Cell RNA - A-431 [nTPM]":"36.0","Cell RNA - A549 [nTPM]":"509.6","Cell RNA - AF22 [nTPM]":"58.4","Cell RNA - AN3-CA [nTPM]":"76.2","Cell RNA - ASC diff [nTPM]":"181.5","Cell RNA - ASC TERT1 [nTPM]":"185.3","Cell RNA - BEWO [nTPM]":"51.3","Cell RNA - BJ [nTPM]":"102.7","Cell RNA - BJ hTERT+ [nTPM]":"113.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"94.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"84.8","Cell RNA - CACO-2 [nTPM]":"76.2","Cell RNA - CAPAN-2 [nTPM]":"115.5","Cell RNA - Daudi [nTPM]":"25.4","Cell RNA - EFO-21 [nTPM]":"63.0","Cell RNA - fHDF\/TERT166 [nTPM]":"133.3","Cell RNA - GAMG [nTPM]":"94.5","Cell RNA - HaCaT [nTPM]":"33.5","Cell RNA - HAP1 [nTPM]":"56.0","Cell RNA - HBEC3-KT [nTPM]":"29.5","Cell RNA - HBF TERT88 [nTPM]":"95.8","Cell RNA - HDLM-2 [nTPM]":"32.1","Cell RNA - HEK 293 [nTPM]":"13.0","Cell RNA - HEL [nTPM]":"26.2","Cell RNA - HeLa [nTPM]":"65.4","Cell RNA - Hep G2 [nTPM]":"595.9","Cell RNA - HHSteC [nTPM]":"72.7","Cell RNA - HL-60 [nTPM]":"34.1","Cell RNA - HMC-1 [nTPM]":"25.3","Cell RNA - HSkMC [nTPM]":"64.4","Cell RNA - hTCEpi [nTPM]":"14.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"160.2","Cell RNA - hTERT-HME1 [nTPM]":"49.8","Cell RNA - hTERT-RPE1 [nTPM]":"78.9","Cell RNA - HUVEC TERT2 [nTPM]":"59.3","Cell RNA - JURKAT [nTPM]":"20.9","Cell RNA - K-562 [nTPM]":"34.1","Cell RNA - Karpas-707 [nTPM]":"17.3","Cell RNA - LHCN-M2 [nTPM]":"67.9","Cell RNA - MCF7 [nTPM]":"89.8","Cell RNA - MOLT-4 [nTPM]":"29.4","Cell RNA - NB-4 [nTPM]":"34.4","Cell RNA - NTERA-2 [nTPM]":"53.1","Cell RNA - OE19 [nTPM]":"194.0","Cell RNA - PC-3 [nTPM]":"46.4","Cell RNA - REH [nTPM]":"48.3","Cell RNA - RH-30 [nTPM]":"95.0","Cell RNA - RPMI-8226 [nTPM]":"22.0","Cell RNA - RPTEC TERT1 [nTPM]":"53.7","Cell RNA - RT4 [nTPM]":"120.0","Cell RNA - SCLC-21H [nTPM]":"31.2","Cell RNA - SH-SY5Y [nTPM]":"46.7","Cell RNA - SiHa [nTPM]":"69.2","Cell RNA - SK-BR-3 [nTPM]":"37.9","Cell RNA - SK-MEL-30 [nTPM]":"45.3","Cell RNA - SuSa [nTPM]":"41.4","Cell RNA - T-47d [nTPM]":"21.0","Cell RNA - THP-1 [nTPM]":"27.0","Cell RNA - TIME [nTPM]":"85.9","Cell RNA - U-138 MG [nTPM]":"97.9","Cell RNA - U-2 OS [nTPM]":"49.1","Cell RNA - U-2197 [nTPM]":"375.8","Cell RNA - U-251 MG [nTPM]":"54.2","Cell RNA - U-266\/70 [nTPM]":"42.1","Cell RNA - U-266\/84 [nTPM]":"33.3","Cell RNA - U-698 [nTPM]":"23.3","Cell RNA - U-87 MG [nTPM]":"86.9","Cell RNA - U-937 [nTPM]":"25.8","Cell RNA - WM-115 [nTPM]":"56.6","Blood RNA - basophil [nTPM]":"30.0","Blood RNA - classical monocyte [nTPM]":"20.9","Blood RNA - eosinophil [nTPM]":"19.7","Blood RNA - gdT-cell [nTPM]":"23.2","Blood RNA - intermediate monocyte [nTPM]":"18.4","Blood RNA - MAIT T-cell [nTPM]":"37.8","Blood RNA - memory B-cell [nTPM]":"18.8","Blood RNA - memory CD4 T-cell [nTPM]":"18.8","Blood RNA - memory CD8 T-cell [nTPM]":"24.9","Blood RNA - myeloid DC [nTPM]":"19.0","Blood RNA - naive B-cell [nTPM]":"18.4","Blood RNA - naive CD4 T-cell [nTPM]":"16.1","Blood RNA - naive CD8 T-cell [nTPM]":"19.4","Blood RNA - neutrophil [nTPM]":"3.8","Blood RNA - NK-cell [nTPM]":"42.3","Blood RNA - non-classical monocyte [nTPM]":"11.2","Blood RNA - plasmacytoid DC [nTPM]":"22.5","Blood RNA - T-reg [nTPM]":"13.5","Blood RNA - total PBMC [nTPM]":"18.8","Brain RNA - amygdala [nTPM]":"6.2","Brain RNA - basal ganglia [nTPM]":"7.3","Brain RNA - cerebellum [nTPM]":"9.4","Brain RNA - cerebral cortex [nTPM]":"9.2","Brain RNA - hippocampal formation [nTPM]":"5.9","Brain RNA - hypothalamus [nTPM]":"8.3","Brain RNA - medulla oblongata [nTPM]":"7.4","Brain RNA - midbrain [nTPM]":"7.7","Brain RNA - pons [nTPM]":"8.0","Brain RNA - spinal cord [nTPM]":"7.6","Brain RNA - thalamus [nTPM]":"8.4","Brain RNA - white matter [nTPM]":"9.7","Single Cell Type RNA - Adipocytes [nTPM]":"19.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.6","Single Cell Type RNA - Astrocytes [nTPM]":"4.6","Single Cell Type RNA - B-cells [nTPM]":"14.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"116.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"73.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"19.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"43.9","Single Cell Type RNA - Bipolar cells [nTPM]":"7.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"115.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"62.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"25.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"21.3","Single Cell Type RNA - dendritic cells [nTPM]":"12.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"207.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"70.5","Single Cell Type RNA - Ductal cells [nTPM]":"54.7","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"78.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"53.8","Single Cell Type RNA - Endothelial cells [nTPM]":"25.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"113.3","Single Cell Type RNA - Erythroid cells [nTPM]":"9.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"345.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"78.8","Single Cell Type RNA - Fibroblasts [nTPM]":"145.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"184.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"64.8","Single Cell Type RNA - granulocytes [nTPM]":"35.5","Single Cell Type RNA - Granulosa cells [nTPM]":"11.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.7","Single Cell Type RNA - Hepatocytes [nTPM]":"231.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.8","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"114.5","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"20.2","Single Cell Type RNA - Langerhans cells [nTPM]":"33.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"33.2","Single Cell Type RNA - Macrophages [nTPM]":"12.7","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"19.9","Single Cell Type RNA - Muller glia cells [nTPM]":"7.3","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"46.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"195.8","Single Cell Type RNA - Paneth cells [nTPM]":"112.2","Single Cell Type RNA - Peritubular cells [nTPM]":"29.0","Single Cell Type RNA - Plasma cells [nTPM]":"21.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"127.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"81.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"79.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"65.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.2","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"39.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"57.5","Single Cell Type RNA - Spermatocytes [nTPM]":"6.5","Single Cell Type RNA - Spermatogonia [nTPM]":"5.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"102.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"40.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"29.0","Single Cell Type RNA - T-cells [nTPM]":"11.7","Single Cell Type RNA - Theca cells [nTPM]":"12.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"152.4","Single Cell Type RNA - Urothelial cells [nTPM]":"86.4"},{"Gene":"UGP2","Gene synonym":["SVUGP2","UGP1","UGPP1"],"Ensembl":"ENSG00000169764","Gene description":"UDP-glucose pyrophosphorylase 2","Uniprot":["Q16851"],"Chromosome":"2","Position":"63840952-63891562","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Nucleotidyltransferase","Transferase"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"858.6","tongue":"756.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"849.9","Hepatocytes":"559.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"417.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034696","HPA034697","HPA064836"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Centrosome","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"13000000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 30: Mammary glandular cells - Lactation","Subcellular main location":["Centrosome","Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA034696":"AB_10670171","HPA034697":"AB_2674287","HPA064836":"AB_2685365"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.50e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-2"},"Tissue RNA - adipose tissue [nTPM]":"267.3","Tissue RNA - adrenal gland [nTPM]":"72.0","Tissue RNA - amygdala [nTPM]":"79.8","Tissue RNA - appendix [nTPM]":"65.8","Tissue RNA - basal ganglia [nTPM]":"89.3","Tissue RNA - bone marrow [nTPM]":"40.1","Tissue RNA - breast [nTPM]":"119.7","Tissue RNA - cerebellum [nTPM]":"72.7","Tissue RNA - cerebral cortex [nTPM]":"109.8","Tissue RNA - cervix [nTPM]":"65.9","Tissue RNA - choroid plexus [nTPM]":"78.8","Tissue RNA - colon [nTPM]":"177.9","Tissue RNA - duodenum [nTPM]":"66.0","Tissue RNA - endometrium 1 [nTPM]":"75.2","Tissue RNA - epididymis [nTPM]":"50.6","Tissue RNA - esophagus [nTPM]":"97.5","Tissue RNA - fallopian tube [nTPM]":"68.9","Tissue RNA - gallbladder [nTPM]":"60.7","Tissue RNA - heart muscle [nTPM]":"232.5","Tissue RNA - hippocampal formation [nTPM]":"87.9","Tissue RNA - hypothalamus [nTPM]":"81.4","Tissue RNA - kidney [nTPM]":"105.4","Tissue RNA - liver [nTPM]":"858.6","Tissue RNA - lung [nTPM]":"65.4","Tissue RNA - lymph node [nTPM]":"65.7","Tissue RNA - medulla oblongata [nTPM]":"77.7","Tissue RNA - midbrain [nTPM]":"77.0","Tissue RNA - ovary [nTPM]":"47.0","Tissue RNA - pancreas [nTPM]":"74.4","Tissue RNA - parathyroid gland [nTPM]":"113.3","Tissue RNA - pituitary gland [nTPM]":"49.8","Tissue RNA - placenta [nTPM]":"137.8","Tissue RNA - pons [nTPM]":"77.6","Tissue RNA - prostate [nTPM]":"57.4","Tissue RNA - rectum [nTPM]":"159.3","Tissue RNA - retina [nTPM]":"36.8","Tissue RNA - salivary gland [nTPM]":"92.9","Tissue RNA - seminal vesicle [nTPM]":"66.2","Tissue RNA - skeletal muscle [nTPM]":"498.0","Tissue RNA - skin 1 [nTPM]":"59.1","Tissue RNA - small intestine [nTPM]":"67.6","Tissue RNA - smooth muscle [nTPM]":"78.5","Tissue RNA - spinal cord [nTPM]":"73.2","Tissue RNA - spleen [nTPM]":"50.8","Tissue RNA - stomach 1 [nTPM]":"69.5","Tissue RNA - testis [nTPM]":"38.3","Tissue RNA - thalamus [nTPM]":"83.3","Tissue RNA - thymus [nTPM]":"106.2","Tissue RNA - thyroid gland [nTPM]":"64.5","Tissue RNA - tongue [nTPM]":"756.1","Tissue RNA - tonsil [nTPM]":"73.7","Tissue RNA - urinary bladder [nTPM]":"88.4","Tissue RNA - vagina [nTPM]":"63.7","Tissue RNA - white matter [nTPM]":"91.8","Cell RNA - A-431 [nTPM]":"122.3","Cell RNA - A549 [nTPM]":"77.6","Cell RNA - AF22 [nTPM]":"63.1","Cell RNA - AN3-CA [nTPM]":"42.0","Cell RNA - ASC diff [nTPM]":"176.1","Cell RNA - ASC TERT1 [nTPM]":"222.4","Cell RNA - BEWO [nTPM]":"220.6","Cell RNA - BJ [nTPM]":"129.1","Cell RNA - BJ hTERT+ [nTPM]":"116.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"82.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"89.4","Cell RNA - CACO-2 [nTPM]":"170.0","Cell RNA - CAPAN-2 [nTPM]":"104.5","Cell RNA - Daudi [nTPM]":"149.5","Cell RNA - EFO-21 [nTPM]":"48.3","Cell RNA - fHDF\/TERT166 [nTPM]":"165.6","Cell RNA - GAMG [nTPM]":"79.9","Cell RNA - HaCaT [nTPM]":"57.4","Cell RNA - HAP1 [nTPM]":"73.4","Cell RNA - HBEC3-KT [nTPM]":"102.6","Cell RNA - HBF TERT88 [nTPM]":"137.0","Cell RNA - HDLM-2 [nTPM]":"99.2","Cell RNA - HEK 293 [nTPM]":"35.7","Cell RNA - HEL [nTPM]":"86.5","Cell RNA - HeLa [nTPM]":"50.4","Cell RNA - Hep G2 [nTPM]":"117.9","Cell RNA - HHSteC [nTPM]":"87.0","Cell RNA - HL-60 [nTPM]":"79.1","Cell RNA - HMC-1 [nTPM]":"73.9","Cell RNA - HSkMC [nTPM]":"148.1","Cell RNA - hTCEpi [nTPM]":"175.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"76.1","Cell RNA - hTERT-HME1 [nTPM]":"80.3","Cell RNA - hTERT-RPE1 [nTPM]":"108.4","Cell RNA - HUVEC TERT2 [nTPM]":"119.4","Cell RNA - JURKAT [nTPM]":"38.9","Cell RNA - K-562 [nTPM]":"48.2","Cell RNA - Karpas-707 [nTPM]":"58.1","Cell RNA - LHCN-M2 [nTPM]":"327.8","Cell RNA - MCF7 [nTPM]":"56.7","Cell RNA - MOLT-4 [nTPM]":"104.6","Cell RNA - NB-4 [nTPM]":"75.2","Cell RNA - NTERA-2 [nTPM]":"122.9","Cell RNA - OE19 [nTPM]":"207.7","Cell RNA - PC-3 [nTPM]":"50.1","Cell RNA - REH [nTPM]":"80.4","Cell RNA - RH-30 [nTPM]":"117.9","Cell RNA - RPMI-8226 [nTPM]":"84.5","Cell RNA - RPTEC TERT1 [nTPM]":"147.4","Cell RNA - RT4 [nTPM]":"77.7","Cell RNA - SCLC-21H [nTPM]":"36.5","Cell RNA - SH-SY5Y [nTPM]":"29.6","Cell RNA - SiHa [nTPM]":"103.3","Cell RNA - SK-BR-3 [nTPM]":"149.8","Cell RNA - SK-MEL-30 [nTPM]":"64.3","Cell RNA - SuSa [nTPM]":"162.6","Cell RNA - T-47d [nTPM]":"51.7","Cell RNA - THP-1 [nTPM]":"59.2","Cell RNA - TIME [nTPM]":"144.3","Cell RNA - U-138 MG [nTPM]":"84.4","Cell RNA - U-2 OS [nTPM]":"125.9","Cell RNA - U-2197 [nTPM]":"113.8","Cell RNA - U-251 MG [nTPM]":"90.5","Cell RNA - U-266\/70 [nTPM]":"101.3","Cell RNA - U-266\/84 [nTPM]":"51.4","Cell RNA - U-698 [nTPM]":"174.9","Cell RNA - U-87 MG [nTPM]":"99.2","Cell RNA - U-937 [nTPM]":"122.7","Cell RNA - WM-115 [nTPM]":"225.7","Blood RNA - basophil [nTPM]":"417.1","Blood RNA - classical monocyte [nTPM]":"33.0","Blood RNA - eosinophil [nTPM]":"53.1","Blood RNA - gdT-cell [nTPM]":"48.0","Blood RNA - intermediate monocyte [nTPM]":"40.7","Blood RNA - MAIT T-cell [nTPM]":"51.8","Blood RNA - memory B-cell [nTPM]":"33.0","Blood RNA - memory CD4 T-cell [nTPM]":"53.6","Blood RNA - memory CD8 T-cell [nTPM]":"50.1","Blood RNA - myeloid DC [nTPM]":"27.9","Blood RNA - naive B-cell [nTPM]":"31.8","Blood RNA - naive CD4 T-cell [nTPM]":"57.6","Blood RNA - naive CD8 T-cell [nTPM]":"53.6","Blood RNA - neutrophil [nTPM]":"45.4","Blood RNA - NK-cell [nTPM]":"70.0","Blood RNA - non-classical monocyte [nTPM]":"39.5","Blood RNA - plasmacytoid DC [nTPM]":"29.7","Blood RNA - T-reg [nTPM]":"127.2","Blood RNA - total PBMC [nTPM]":"62.0","Brain RNA - amygdala [nTPM]":"79.8","Brain RNA - basal ganglia [nTPM]":"89.3","Brain RNA - cerebellum [nTPM]":"72.7","Brain RNA - cerebral cortex [nTPM]":"109.8","Brain RNA - hippocampal formation [nTPM]":"87.9","Brain RNA - hypothalamus [nTPM]":"81.4","Brain RNA - medulla oblongata [nTPM]":"77.7","Brain RNA - midbrain [nTPM]":"77.0","Brain RNA - pons [nTPM]":"77.6","Brain RNA - spinal cord [nTPM]":"73.2","Brain RNA - thalamus [nTPM]":"83.3","Brain RNA - white matter [nTPM]":"91.8","Single Cell Type RNA - Adipocytes [nTPM]":"73.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"54.0","Single Cell Type RNA - Astrocytes [nTPM]":"107.4","Single Cell Type RNA - B-cells [nTPM]":"65.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"75.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"87.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"245.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"34.7","Single Cell Type RNA - Bipolar cells [nTPM]":"49.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"360.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"87.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"264.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"104.4","Single Cell Type RNA - Club cells [nTPM]":"171.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"47.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"64.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"414.3","Single Cell Type RNA - dendritic cells [nTPM]":"81.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"849.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"242.6","Single Cell Type RNA - Ductal cells [nTPM]":"140.6","Single Cell Type RNA - Early spermatids [nTPM]":"91.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"53.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"106.3","Single Cell Type RNA - Endothelial cells [nTPM]":"69.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"44.5","Single Cell Type RNA - Erythroid cells [nTPM]":"56.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"86.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"103.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"445.5","Single Cell Type RNA - Fibroblasts [nTPM]":"159.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"79.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"49.5","Single Cell Type RNA - granulocytes [nTPM]":"67.8","Single Cell Type RNA - Granulosa cells [nTPM]":"42.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"63.5","Single Cell Type RNA - Hepatocytes [nTPM]":"559.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"120.9","Single Cell Type RNA - Horizontal cells [nTPM]":"87.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"78.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"179.8","Single Cell Type RNA - Ionocytes [nTPM]":"144.5","Single Cell Type RNA - Kupffer cells [nTPM]":"102.4","Single Cell Type RNA - Langerhans cells [nTPM]":"90.2","Single Cell Type RNA - Late spermatids [nTPM]":"86.1","Single Cell Type RNA - Leydig cells [nTPM]":"79.2","Single Cell Type RNA - Macrophages [nTPM]":"89.1","Single Cell Type RNA - Melanocytes [nTPM]":"96.0","Single Cell Type RNA - Microglial cells [nTPM]":"62.8","Single Cell Type RNA - monocytes [nTPM]":"139.7","Single Cell Type RNA - Muller glia cells [nTPM]":"58.8","Single Cell Type RNA - NK-cells [nTPM]":"154.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"37.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"79.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"91.6","Single Cell Type RNA - Paneth cells [nTPM]":"313.9","Single Cell Type RNA - Peritubular cells [nTPM]":"77.5","Single Cell Type RNA - Plasma cells [nTPM]":"60.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"81.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"176.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"284.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"139.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"57.3","Single Cell Type RNA - Sertoli cells [nTPM]":"72.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"50.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"129.2","Single Cell Type RNA - Spermatocytes [nTPM]":"84.9","Single Cell Type RNA - Spermatogonia [nTPM]":"54.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"50.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"57.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"472.8","Single Cell Type RNA - T-cells [nTPM]":"143.1","Single Cell Type RNA - Theca cells [nTPM]":"90.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"189.5","Single Cell Type RNA - Urothelial cells [nTPM]":"109.1"},{"Gene":"UGT1A1","Gene synonym":["GNT1","UGT1","UGT1A"],"Ensembl":"ENSG00000241635","Gene description":"UDP glucuronosyltransferase family 1 member A1","Uniprot":["P22309"],"Chromosome":"2","Position":"233760270-233773300","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"26","RNA tissue specific nTPM":{"intestine":"201.2","liver":"322.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Hepatocytes":"105.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"19","RNA cancer specific FPKM":{"liver cancer":"16.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"1.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"14.0","OE19":"64.5","RT4":"34.7"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-4"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.6","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"1.5","Tissue RNA - cerebral cortex [nTPM]":"0.8","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"3.0","Tissue RNA - duodenum [nTPM]":"201.2","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"3.5","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"1.0","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"0.8","Tissue RNA - kidney [nTPM]":"4.0","Tissue RNA - liver [nTPM]":"322.4","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"2.4","Tissue RNA - retina [nTPM]":"0.9","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"1.8","Tissue RNA - small intestine [nTPM]":"79.2","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"2.4","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"10.0","Tissue RNA - vagina [nTPM]":"0.9","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"1.1","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.6","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"5.4","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"2.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"14.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.6","Cell RNA - Hep G2 [nTPM]":"1.6","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.6","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.8","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"64.5","Cell RNA - PC-3 [nTPM]":"6.5","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"34.7","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.4","Cell RNA - SiHa [nTPM]":"2.6","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.7","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.9","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"1.4","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.6","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"1.5","Brain RNA - cerebral cortex [nTPM]":"0.8","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"0.8","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"2.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"105.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.4","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"1.6","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.7","Single Cell Type RNA - Urothelial cells [nTPM]":"7.3"},{"Gene":"UHRF1","Gene synonym":["FLJ21925","ICBP90","Np95","RNF106","TDRD22"],"Ensembl":"ENSG00000276043","Gene description":"Ubiquitin like with PHD and ring finger domains 1","Uniprot":["Q96T88"],"Chromosome":"19","Position":"4903080-4962154","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA damage","DNA repair","Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["Chromatin regulator","DNA-binding","Repressor","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"bone marrow":"27.0","lymphoid tissue":"67.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"49.7","Plasma cells":"21.0","Squamous epithelial cells":"15.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"4.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"4.8","T-cells":"2.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MOLT-4":"450.9","REH":"1004.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049408","HPA055446"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 14: REH - Unknown function","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA049408":"AB_2756317","HPA055446":"AB_2732597"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.83e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.63e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.81e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.52e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.0","Tissue RNA - adrenal gland [nTPM]":"0.9","Tissue RNA - amygdala [nTPM]":"2.1","Tissue RNA - appendix [nTPM]":"9.6","Tissue RNA - basal ganglia [nTPM]":"2.7","Tissue RNA - bone marrow [nTPM]":"27.0","Tissue RNA - breast [nTPM]":"1.7","Tissue RNA - cerebellum [nTPM]":"2.1","Tissue RNA - cerebral cortex [nTPM]":"2.3","Tissue RNA - cervix [nTPM]":"1.6","Tissue RNA - choroid plexus [nTPM]":"1.8","Tissue RNA - colon [nTPM]":"2.9","Tissue RNA - duodenum [nTPM]":"3.7","Tissue RNA - endometrium 1 [nTPM]":"1.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"6.5","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"2.0","Tissue RNA - hypothalamus [nTPM]":"2.2","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"0.9","Tissue RNA - lung [nTPM]":"1.3","Tissue RNA - lymph node [nTPM]":"15.8","Tissue RNA - medulla oblongata [nTPM]":"2.8","Tissue RNA - midbrain [nTPM]":"2.8","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.6","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"2.1","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"0.6","Tissue RNA - rectum [nTPM]":"2.6","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"1.5","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"1.2","Tissue RNA - skin 1 [nTPM]":"3.4","Tissue RNA - small intestine [nTPM]":"3.9","Tissue RNA - smooth muscle [nTPM]":"1.9","Tissue RNA - spinal cord [nTPM]":"1.9","Tissue RNA - spleen [nTPM]":"3.7","Tissue RNA - stomach 1 [nTPM]":"3.3","Tissue RNA - testis [nTPM]":"5.2","Tissue RNA - thalamus [nTPM]":"3.5","Tissue RNA - thymus [nTPM]":"67.2","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"10.3","Tissue RNA - urinary bladder [nTPM]":"1.6","Tissue RNA - vagina [nTPM]":"2.5","Tissue RNA - white matter [nTPM]":"4.6","Cell RNA - A-431 [nTPM]":"111.3","Cell RNA - A549 [nTPM]":"78.7","Cell RNA - AF22 [nTPM]":"116.6","Cell RNA - AN3-CA [nTPM]":"83.4","Cell RNA - ASC diff [nTPM]":"3.3","Cell RNA - ASC TERT1 [nTPM]":"13.3","Cell RNA - BEWO [nTPM]":"18.5","Cell RNA - BJ [nTPM]":"88.3","Cell RNA - BJ hTERT+ [nTPM]":"42.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"89.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"86.8","Cell RNA - CACO-2 [nTPM]":"94.6","Cell RNA - CAPAN-2 [nTPM]":"54.9","Cell RNA - Daudi [nTPM]":"62.7","Cell RNA - EFO-21 [nTPM]":"21.1","Cell RNA - fHDF\/TERT166 [nTPM]":"39.4","Cell RNA - GAMG [nTPM]":"32.7","Cell RNA - HaCaT [nTPM]":"54.1","Cell RNA - HAP1 [nTPM]":"81.2","Cell RNA - HBEC3-KT [nTPM]":"47.7","Cell RNA - HBF TERT88 [nTPM]":"63.0","Cell RNA - HDLM-2 [nTPM]":"102.7","Cell RNA - HEK 293 [nTPM]":"92.2","Cell RNA - HEL [nTPM]":"54.3","Cell RNA - HeLa [nTPM]":"74.3","Cell RNA - Hep G2 [nTPM]":"102.4","Cell RNA - HHSteC [nTPM]":"1.3","Cell RNA - HL-60 [nTPM]":"135.1","Cell RNA - HMC-1 [nTPM]":"78.9","Cell RNA - HSkMC [nTPM]":"6.5","Cell RNA - hTCEpi [nTPM]":"3.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"48.9","Cell RNA - hTERT-HME1 [nTPM]":"12.6","Cell RNA - hTERT-RPE1 [nTPM]":"14.1","Cell RNA - HUVEC TERT2 [nTPM]":"27.2","Cell RNA - JURKAT [nTPM]":"97.2","Cell RNA - K-562 [nTPM]":"79.3","Cell RNA - Karpas-707 [nTPM]":"70.5","Cell RNA - LHCN-M2 [nTPM]":"54.5","Cell RNA - MCF7 [nTPM]":"86.7","Cell RNA - MOLT-4 [nTPM]":"450.9","Cell RNA - NB-4 [nTPM]":"82.5","Cell RNA - NTERA-2 [nTPM]":"52.5","Cell RNA - OE19 [nTPM]":"40.0","Cell RNA - PC-3 [nTPM]":"84.3","Cell RNA - REH [nTPM]":"1004.5","Cell RNA - RH-30 [nTPM]":"259.7","Cell RNA - RPMI-8226 [nTPM]":"45.4","Cell RNA - RPTEC TERT1 [nTPM]":"24.9","Cell RNA - RT4 [nTPM]":"80.1","Cell RNA - SCLC-21H [nTPM]":"86.0","Cell RNA - SH-SY5Y [nTPM]":"68.5","Cell RNA - SiHa [nTPM]":"69.2","Cell RNA - SK-BR-3 [nTPM]":"37.7","Cell RNA - SK-MEL-30 [nTPM]":"12.1","Cell RNA - SuSa [nTPM]":"18.8","Cell RNA - T-47d [nTPM]":"68.2","Cell RNA - THP-1 [nTPM]":"127.6","Cell RNA - TIME [nTPM]":"34.2","Cell RNA - U-138 MG [nTPM]":"94.6","Cell RNA - U-2 OS [nTPM]":"76.7","Cell RNA - U-2197 [nTPM]":"124.3","Cell RNA - U-251 MG [nTPM]":"108.3","Cell RNA - U-266\/70 [nTPM]":"29.8","Cell RNA - U-266\/84 [nTPM]":"33.1","Cell RNA - U-698 [nTPM]":"183.5","Cell RNA - U-87 MG [nTPM]":"54.8","Cell RNA - U-937 [nTPM]":"129.7","Cell RNA - WM-115 [nTPM]":"123.3","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"1.0","Blood RNA - myeloid DC [nTPM]":"1.3","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.8","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"4.8","Blood RNA - T-reg [nTPM]":"2.3","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"2.1","Brain RNA - basal ganglia [nTPM]":"2.7","Brain RNA - cerebellum [nTPM]":"2.1","Brain RNA - cerebral cortex [nTPM]":"2.3","Brain RNA - hippocampal formation [nTPM]":"2.0","Brain RNA - hypothalamus [nTPM]":"2.2","Brain RNA - medulla oblongata [nTPM]":"2.8","Brain RNA - midbrain [nTPM]":"2.8","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"1.9","Brain RNA - thalamus [nTPM]":"3.5","Brain RNA - white matter [nTPM]":"4.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"2.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"2.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.6","Single Cell Type RNA - dendritic cells [nTPM]":"6.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.2","Single Cell Type RNA - Early spermatids [nTPM]":"2.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.8","Single Cell Type RNA - Endothelial cells [nTPM]":"2.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"49.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.8","Single Cell Type RNA - Fibroblasts [nTPM]":"4.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"10.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.9","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"3.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"2.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.6","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.2","Single Cell Type RNA - Paneth cells [nTPM]":"1.9","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"21.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.1","Single Cell Type RNA - Spermatocytes [nTPM]":"6.1","Single Cell Type RNA - Spermatogonia [nTPM]":"11.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - T-cells [nTPM]":"3.7","Single Cell Type RNA - Theca cells [nTPM]":"1.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.3","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"UHRF2","Gene synonym":["MGC33463","NIRF","RNF107","TDRD23","URF2"],"Ensembl":"ENSG00000147854","Gene description":"Ubiquitin like with PHD and ring finger domains 2","Uniprot":["Q96PU4"],"Chromosome":"9","Position":"6413151-6507054","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","Ubl conjugation pathway"],"Molecular function":["DNA-binding","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"78.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026633","HPA026697"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 43: Cardiomyocytes - Nuclear processes","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA026633":"AB_2732431","HPA026697":"AB_2732432"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.0","Tissue RNA - adrenal gland [nTPM]":"8.1","Tissue RNA - amygdala [nTPM]":"8.2","Tissue RNA - appendix [nTPM]":"9.9","Tissue RNA - basal ganglia [nTPM]":"10.3","Tissue RNA - bone marrow [nTPM]":"44.6","Tissue RNA - breast [nTPM]":"9.7","Tissue RNA - cerebellum [nTPM]":"14.9","Tissue RNA - cerebral cortex [nTPM]":"10.4","Tissue RNA - cervix [nTPM]":"12.9","Tissue RNA - choroid plexus [nTPM]":"10.4","Tissue RNA - colon [nTPM]":"11.6","Tissue RNA - duodenum [nTPM]":"6.2","Tissue RNA - endometrium 1 [nTPM]":"12.9","Tissue RNA - epididymis [nTPM]":"10.0","Tissue RNA - esophagus [nTPM]":"8.3","Tissue RNA - fallopian tube [nTPM]":"9.9","Tissue RNA - gallbladder [nTPM]":"7.9","Tissue RNA - heart muscle [nTPM]":"7.2","Tissue RNA - hippocampal formation [nTPM]":"8.7","Tissue RNA - hypothalamus [nTPM]":"9.2","Tissue RNA - kidney [nTPM]":"8.1","Tissue RNA - liver [nTPM]":"7.9","Tissue RNA - lung [nTPM]":"7.8","Tissue RNA - lymph node [nTPM]":"17.3","Tissue RNA - medulla oblongata [nTPM]":"9.4","Tissue RNA - midbrain [nTPM]":"8.6","Tissue RNA - ovary [nTPM]":"12.4","Tissue RNA - pancreas [nTPM]":"10.7","Tissue RNA - parathyroid gland [nTPM]":"9.7","Tissue RNA - pituitary gland [nTPM]":"5.4","Tissue RNA - placenta [nTPM]":"12.1","Tissue RNA - pons [nTPM]":"9.4","Tissue RNA - prostate [nTPM]":"15.3","Tissue RNA - rectum [nTPM]":"9.2","Tissue RNA - retina [nTPM]":"9.2","Tissue RNA - salivary gland [nTPM]":"8.5","Tissue RNA - seminal vesicle [nTPM]":"12.6","Tissue RNA - skeletal muscle [nTPM]":"11.0","Tissue RNA - skin 1 [nTPM]":"7.7","Tissue RNA - small intestine [nTPM]":"8.5","Tissue RNA - smooth muscle [nTPM]":"14.0","Tissue RNA - spinal cord [nTPM]":"8.8","Tissue RNA - spleen [nTPM]":"10.4","Tissue RNA - stomach 1 [nTPM]":"8.3","Tissue RNA - testis [nTPM]":"8.4","Tissue RNA - thalamus [nTPM]":"10.0","Tissue RNA - thymus [nTPM]":"21.2","Tissue RNA - thyroid gland [nTPM]":"8.1","Tissue RNA - tongue [nTPM]":"11.9","Tissue RNA - tonsil [nTPM]":"16.6","Tissue RNA - urinary bladder [nTPM]":"11.4","Tissue RNA - vagina [nTPM]":"10.1","Tissue RNA - white matter [nTPM]":"14.3","Cell RNA - A-431 [nTPM]":"18.1","Cell RNA - A549 [nTPM]":"18.8","Cell RNA - AF22 [nTPM]":"26.7","Cell RNA - AN3-CA [nTPM]":"11.9","Cell RNA - ASC diff [nTPM]":"21.4","Cell RNA - ASC TERT1 [nTPM]":"30.7","Cell RNA - BEWO [nTPM]":"20.5","Cell RNA - BJ [nTPM]":"43.9","Cell RNA - BJ hTERT+ [nTPM]":"23.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"41.2","Cell RNA - CACO-2 [nTPM]":"12.4","Cell RNA - CAPAN-2 [nTPM]":"12.0","Cell RNA - Daudi [nTPM]":"26.9","Cell RNA - EFO-21 [nTPM]":"9.2","Cell RNA - fHDF\/TERT166 [nTPM]":"19.2","Cell RNA - GAMG [nTPM]":"21.8","Cell RNA - HaCaT [nTPM]":"11.9","Cell RNA - HAP1 [nTPM]":"24.6","Cell RNA - HBEC3-KT [nTPM]":"22.5","Cell RNA - HBF TERT88 [nTPM]":"36.0","Cell RNA - HDLM-2 [nTPM]":"53.6","Cell RNA - HEK 293 [nTPM]":"14.9","Cell RNA - HEL [nTPM]":"46.3","Cell RNA - HeLa [nTPM]":"36.2","Cell RNA - Hep G2 [nTPM]":"19.7","Cell RNA - HHSteC [nTPM]":"17.8","Cell RNA - HL-60 [nTPM]":"19.3","Cell RNA - HMC-1 [nTPM]":"16.1","Cell RNA - HSkMC [nTPM]":"13.5","Cell RNA - hTCEpi [nTPM]":"14.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.4","Cell RNA - hTERT-HME1 [nTPM]":"44.5","Cell RNA - hTERT-RPE1 [nTPM]":"44.4","Cell RNA - HUVEC TERT2 [nTPM]":"93.2","Cell RNA - JURKAT [nTPM]":"25.4","Cell RNA - K-562 [nTPM]":"5.1","Cell RNA - Karpas-707 [nTPM]":"24.0","Cell RNA - LHCN-M2 [nTPM]":"56.0","Cell RNA - MCF7 [nTPM]":"5.9","Cell RNA - MOLT-4 [nTPM]":"37.0","Cell RNA - NB-4 [nTPM]":"79.2","Cell RNA - NTERA-2 [nTPM]":"10.8","Cell RNA - OE19 [nTPM]":"24.8","Cell RNA - PC-3 [nTPM]":"14.8","Cell RNA - REH [nTPM]":"43.1","Cell RNA - RH-30 [nTPM]":"12.4","Cell RNA - RPMI-8226 [nTPM]":"8.7","Cell RNA - RPTEC TERT1 [nTPM]":"17.2","Cell RNA - RT4 [nTPM]":"11.3","Cell RNA - SCLC-21H [nTPM]":"24.8","Cell RNA - SH-SY5Y [nTPM]":"9.4","Cell RNA - SiHa [nTPM]":"16.6","Cell RNA - SK-BR-3 [nTPM]":"11.0","Cell RNA - SK-MEL-30 [nTPM]":"25.6","Cell RNA - SuSa [nTPM]":"32.1","Cell RNA - T-47d [nTPM]":"14.0","Cell RNA - THP-1 [nTPM]":"41.9","Cell RNA - TIME [nTPM]":"78.6","Cell RNA - U-138 MG [nTPM]":"25.2","Cell RNA - U-2 OS [nTPM]":"10.0","Cell RNA - U-2197 [nTPM]":"11.0","Cell RNA - U-251 MG [nTPM]":"34.4","Cell RNA - U-266\/70 [nTPM]":"7.2","Cell RNA - U-266\/84 [nTPM]":"23.2","Cell RNA - U-698 [nTPM]":"30.4","Cell RNA - U-87 MG [nTPM]":"12.4","Cell RNA - U-937 [nTPM]":"18.2","Cell RNA - WM-115 [nTPM]":"10.2","Blood RNA - basophil [nTPM]":"4.0","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"2.7","Blood RNA - gdT-cell [nTPM]":"1.2","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.8","Blood RNA - memory CD8 T-cell [nTPM]":"1.0","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"2.9","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.2","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"1.9","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"8.2","Brain RNA - basal ganglia [nTPM]":"10.3","Brain RNA - cerebellum [nTPM]":"14.9","Brain RNA - cerebral cortex [nTPM]":"10.4","Brain RNA - hippocampal formation [nTPM]":"8.7","Brain RNA - hypothalamus [nTPM]":"9.2","Brain RNA - medulla oblongata [nTPM]":"9.4","Brain RNA - midbrain [nTPM]":"8.6","Brain RNA - pons [nTPM]":"9.4","Brain RNA - spinal cord [nTPM]":"8.8","Brain RNA - thalamus [nTPM]":"10.0","Brain RNA - white matter [nTPM]":"14.3","Single Cell Type RNA - Adipocytes [nTPM]":"27.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.4","Single Cell Type RNA - Astrocytes [nTPM]":"24.2","Single Cell Type RNA - B-cells [nTPM]":"33.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"21.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.0","Single Cell Type RNA - Bipolar cells [nTPM]":"22.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"59.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"8.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.2","Single Cell Type RNA - dendritic cells [nTPM]":"31.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.2","Single Cell Type RNA - Early spermatids [nTPM]":"23.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.9","Single Cell Type RNA - Endothelial cells [nTPM]":"24.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.1","Single Cell Type RNA - Erythroid cells [nTPM]":"34.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"44.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.9","Single Cell Type RNA - Fibroblasts [nTPM]":"16.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.5","Single Cell Type RNA - granulocytes [nTPM]":"17.7","Single Cell Type RNA - Granulosa cells [nTPM]":"27.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.8","Single Cell Type RNA - Hepatocytes [nTPM]":"14.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.7","Single Cell Type RNA - Horizontal cells [nTPM]":"28.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"53.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.8","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"12.6","Single Cell Type RNA - Langerhans cells [nTPM]":"9.3","Single Cell Type RNA - Late spermatids [nTPM]":"8.1","Single Cell Type RNA - Leydig cells [nTPM]":"19.3","Single Cell Type RNA - Macrophages [nTPM]":"15.6","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"51.5","Single Cell Type RNA - monocytes [nTPM]":"12.5","Single Cell Type RNA - Muller glia cells [nTPM]":"6.4","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"46.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"78.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.2","Single Cell Type RNA - Paneth cells [nTPM]":"14.4","Single Cell Type RNA - Peritubular cells [nTPM]":"14.7","Single Cell Type RNA - Plasma cells [nTPM]":"30.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"34.8","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.8","Single Cell Type RNA - Spermatocytes [nTPM]":"46.2","Single Cell Type RNA - Spermatogonia [nTPM]":"23.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"19.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.9","Single Cell Type RNA - T-cells [nTPM]":"29.0","Single Cell Type RNA - Theca cells [nTPM]":"13.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.6","Single Cell Type RNA - Urothelial cells [nTPM]":"9.8"},{"Gene":"ULK4","Gene synonym":["FAM7C1","FLJ20574","REC01035"],"Ensembl":"ENSG00000168038","Gene description":"Unc-51 like kinase 4","Uniprot":["Q96C45"],"Chromosome":"3","Position":"41246599-41962130","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"23.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"352.3","Excitatory neurons":"108.6","Inhibitory neurons":"99.2","Late spermatids":"405.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017930"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":["Nucleoplasm","Mitochondria","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA017930":"AB_1858615"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.72e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.7","Tissue RNA - adrenal gland [nTPM]":"3.1","Tissue RNA - amygdala [nTPM]":"1.6","Tissue RNA - appendix [nTPM]":"2.9","Tissue RNA - basal ganglia [nTPM]":"2.1","Tissue RNA - bone marrow [nTPM]":"8.5","Tissue RNA - breast [nTPM]":"2.5","Tissue RNA - cerebellum [nTPM]":"0.4","Tissue RNA - cerebral cortex [nTPM]":"1.7","Tissue RNA - cervix [nTPM]":"8.5","Tissue RNA - choroid plexus [nTPM]":"16.9","Tissue RNA - colon [nTPM]":"1.6","Tissue RNA - duodenum [nTPM]":"1.2","Tissue RNA - endometrium 1 [nTPM]":"6.6","Tissue RNA - epididymis [nTPM]":"4.5","Tissue RNA - esophagus [nTPM]":"1.5","Tissue RNA - fallopian tube [nTPM]":"9.0","Tissue RNA - gallbladder [nTPM]":"1.9","Tissue RNA - heart muscle [nTPM]":"8.6","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"2.5","Tissue RNA - kidney [nTPM]":"3.9","Tissue RNA - liver [nTPM]":"2.1","Tissue RNA - lung [nTPM]":"3.5","Tissue RNA - lymph node [nTPM]":"3.0","Tissue RNA - medulla oblongata [nTPM]":"6.9","Tissue RNA - midbrain [nTPM]":"7.6","Tissue RNA - ovary [nTPM]":"2.1","Tissue RNA - pancreas [nTPM]":"2.0","Tissue RNA - parathyroid gland [nTPM]":"8.0","Tissue RNA - pituitary gland [nTPM]":"2.9","Tissue RNA - placenta [nTPM]":"2.7","Tissue RNA - pons [nTPM]":"3.9","Tissue RNA - prostate [nTPM]":"2.2","Tissue RNA - rectum [nTPM]":"1.7","Tissue RNA - retina [nTPM]":"6.0","Tissue RNA - salivary gland [nTPM]":"1.7","Tissue RNA - seminal vesicle [nTPM]":"2.4","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"2.1","Tissue RNA - small intestine [nTPM]":"2.0","Tissue RNA - smooth muscle [nTPM]":"3.5","Tissue RNA - spinal cord [nTPM]":"5.6","Tissue RNA - spleen [nTPM]":"2.0","Tissue RNA - stomach 1 [nTPM]":"2.4","Tissue RNA - testis [nTPM]":"23.4","Tissue RNA - thalamus [nTPM]":"2.5","Tissue RNA - thymus [nTPM]":"3.0","Tissue RNA - thyroid gland [nTPM]":"4.9","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"2.7","Tissue RNA - urinary bladder [nTPM]":"1.9","Tissue RNA - vagina [nTPM]":"3.7","Tissue RNA - white matter [nTPM]":"2.1","Cell RNA - A-431 [nTPM]":"8.3","Cell RNA - A549 [nTPM]":"2.9","Cell RNA - AF22 [nTPM]":"2.8","Cell RNA - AN3-CA [nTPM]":"3.8","Cell RNA - ASC diff [nTPM]":"1.1","Cell RNA - ASC TERT1 [nTPM]":"1.7","Cell RNA - BEWO [nTPM]":"4.8","Cell RNA - BJ [nTPM]":"2.7","Cell RNA - BJ hTERT+ [nTPM]":"2.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.0","Cell RNA - CACO-2 [nTPM]":"1.0","Cell RNA - CAPAN-2 [nTPM]":"2.3","Cell RNA - Daudi [nTPM]":"9.5","Cell RNA - EFO-21 [nTPM]":"1.6","Cell RNA - fHDF\/TERT166 [nTPM]":"6.3","Cell RNA - GAMG [nTPM]":"3.5","Cell RNA - HaCaT [nTPM]":"4.1","Cell RNA - HAP1 [nTPM]":"3.7","Cell RNA - HBEC3-KT [nTPM]":"2.1","Cell RNA - HBF TERT88 [nTPM]":"2.9","Cell RNA - HDLM-2 [nTPM]":"1.5","Cell RNA - HEK 293 [nTPM]":"1.0","Cell RNA - HEL [nTPM]":"2.1","Cell RNA - HeLa [nTPM]":"5.7","Cell RNA - Hep G2 [nTPM]":"3.3","Cell RNA - HHSteC [nTPM]":"4.1","Cell RNA - HL-60 [nTPM]":"6.5","Cell RNA - HMC-1 [nTPM]":"1.8","Cell RNA - HSkMC [nTPM]":"1.6","Cell RNA - hTCEpi [nTPM]":"2.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.1","Cell RNA - hTERT-HME1 [nTPM]":"3.2","Cell RNA - hTERT-RPE1 [nTPM]":"4.4","Cell RNA - HUVEC TERT2 [nTPM]":"2.2","Cell RNA - JURKAT [nTPM]":"6.4","Cell RNA - K-562 [nTPM]":"2.1","Cell RNA - Karpas-707 [nTPM]":"7.5","Cell RNA - LHCN-M2 [nTPM]":"2.3","Cell RNA - MCF7 [nTPM]":"6.4","Cell RNA - MOLT-4 [nTPM]":"8.1","Cell RNA - NB-4 [nTPM]":"4.9","Cell RNA - NTERA-2 [nTPM]":"3.4","Cell RNA - OE19 [nTPM]":"2.1","Cell RNA - PC-3 [nTPM]":"3.4","Cell RNA - REH [nTPM]":"1.7","Cell RNA - RH-30 [nTPM]":"9.1","Cell RNA - RPMI-8226 [nTPM]":"4.5","Cell RNA - RPTEC TERT1 [nTPM]":"7.2","Cell RNA - RT4 [nTPM]":"7.6","Cell RNA - SCLC-21H [nTPM]":"1.6","Cell RNA - SH-SY5Y [nTPM]":"10.3","Cell RNA - SiHa [nTPM]":"3.1","Cell RNA - SK-BR-3 [nTPM]":"1.3","Cell RNA - SK-MEL-30 [nTPM]":"2.8","Cell RNA - SuSa [nTPM]":"1.8","Cell RNA - T-47d [nTPM]":"3.1","Cell RNA - THP-1 [nTPM]":"2.0","Cell RNA - TIME [nTPM]":"6.6","Cell RNA - U-138 MG [nTPM]":"2.0","Cell RNA - U-2 OS [nTPM]":"2.4","Cell RNA - U-2197 [nTPM]":"14.2","Cell RNA - U-251 MG [nTPM]":"2.5","Cell RNA - U-266\/70 [nTPM]":"4.5","Cell RNA - U-266\/84 [nTPM]":"9.0","Cell RNA - U-698 [nTPM]":"3.9","Cell RNA - U-87 MG [nTPM]":"11.5","Cell RNA - U-937 [nTPM]":"6.3","Cell RNA - WM-115 [nTPM]":"2.5","Blood RNA - basophil [nTPM]":"3.7","Blood RNA - classical monocyte [nTPM]":"3.7","Blood RNA - eosinophil [nTPM]":"4.0","Blood RNA - gdT-cell [nTPM]":"5.0","Blood RNA - intermediate monocyte [nTPM]":"4.3","Blood RNA - MAIT T-cell [nTPM]":"4.1","Blood RNA - memory B-cell [nTPM]":"3.7","Blood RNA - memory CD4 T-cell [nTPM]":"5.3","Blood RNA - memory CD8 T-cell [nTPM]":"4.5","Blood RNA - myeloid DC [nTPM]":"3.3","Blood RNA - naive B-cell [nTPM]":"4.7","Blood RNA - naive CD4 T-cell [nTPM]":"4.0","Blood RNA - naive CD8 T-cell [nTPM]":"5.7","Blood RNA - neutrophil [nTPM]":"6.6","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"2.3","Blood RNA - plasmacytoid DC [nTPM]":"3.3","Blood RNA - T-reg [nTPM]":"7.7","Blood RNA - total PBMC [nTPM]":"3.0","Brain RNA - amygdala [nTPM]":"1.6","Brain RNA - basal ganglia [nTPM]":"2.1","Brain RNA - cerebellum [nTPM]":"0.4","Brain RNA - cerebral cortex [nTPM]":"1.7","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"2.5","Brain RNA - medulla oblongata [nTPM]":"6.9","Brain RNA - midbrain [nTPM]":"7.6","Brain RNA - pons [nTPM]":"3.9","Brain RNA - spinal cord [nTPM]":"5.6","Brain RNA - thalamus [nTPM]":"2.5","Brain RNA - white matter [nTPM]":"2.1","Single Cell Type RNA - Adipocytes [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.9","Single Cell Type RNA - Astrocytes [nTPM]":"84.9","Single Cell Type RNA - B-cells [nTPM]":"11.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"5.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"5.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"54.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.1","Single Cell Type RNA - dendritic cells [nTPM]":"9.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.4","Single Cell Type RNA - Early spermatids [nTPM]":"352.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"45.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"27.4","Single Cell Type RNA - Endothelial cells [nTPM]":"6.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"108.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.1","Single Cell Type RNA - Fibroblasts [nTPM]":"8.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"49.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"6.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.3","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"99.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.2","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.1","Single Cell Type RNA - Langerhans cells [nTPM]":"4.0","Single Cell Type RNA - Late spermatids [nTPM]":"405.2","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"6.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"80.6","Single Cell Type RNA - monocytes [nTPM]":"5.9","Single Cell Type RNA - Muller glia cells [nTPM]":"10.4","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"49.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"62.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.7","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"5.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"47.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"26.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.5","Single Cell Type RNA - Spermatocytes [nTPM]":"38.9","Single Cell Type RNA - Spermatogonia [nTPM]":"9.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.2","Single Cell Type RNA - T-cells [nTPM]":"10.8","Single Cell Type RNA - Theca cells [nTPM]":"3.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.9","Single Cell Type RNA - Urothelial cells [nTPM]":"1.2"},{"Gene":"UMPS","Gene synonym":[],"Ensembl":"ENSG00000114491","Gene description":"Uridine monophosphate synthetase","Uniprot":["P11172"],"Chromosome":"3","Position":"124730433-124749273","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Pyrimidine biosynthesis"],"Molecular function":["Decarboxylase","Glycosyltransferase","Lyase","Multifunctional enzyme","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"109.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036178","HPA036179"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9200","Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA036178":"AB_10673002","HPA036179":"AB_10673615"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.20e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.3","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"2.5","Tissue RNA - appendix [nTPM]":"1.2","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"1.3","Tissue RNA - breast [nTPM]":"1.8","Tissue RNA - cerebellum [nTPM]":"2.8","Tissue RNA - cerebral cortex [nTPM]":"2.9","Tissue RNA - cervix [nTPM]":"1.0","Tissue RNA - choroid plexus [nTPM]":"1.1","Tissue RNA - colon [nTPM]":"2.3","Tissue RNA - duodenum [nTPM]":"2.0","Tissue RNA - endometrium 1 [nTPM]":"1.3","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"2.0","Tissue RNA - fallopian tube [nTPM]":"1.8","Tissue RNA - gallbladder [nTPM]":"0.7","Tissue RNA - heart muscle [nTPM]":"0.8","Tissue RNA - hippocampal formation [nTPM]":"2.6","Tissue RNA - hypothalamus [nTPM]":"1.8","Tissue RNA - kidney [nTPM]":"1.8","Tissue RNA - liver [nTPM]":"2.6","Tissue RNA - lung [nTPM]":"0.9","Tissue RNA - lymph node [nTPM]":"1.4","Tissue RNA - medulla oblongata [nTPM]":"2.8","Tissue RNA - midbrain [nTPM]":"2.1","Tissue RNA - ovary [nTPM]":"1.9","Tissue RNA - pancreas [nTPM]":"2.1","Tissue RNA - parathyroid gland [nTPM]":"1.5","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"0.7","Tissue RNA - pons [nTPM]":"2.3","Tissue RNA - prostate [nTPM]":"1.4","Tissue RNA - rectum [nTPM]":"1.6","Tissue RNA - retina [nTPM]":"1.8","Tissue RNA - salivary gland [nTPM]":"1.3","Tissue RNA - seminal vesicle [nTPM]":"0.7","Tissue RNA - skeletal muscle [nTPM]":"3.1","Tissue RNA - skin 1 [nTPM]":"2.3","Tissue RNA - small intestine [nTPM]":"2.1","Tissue RNA - smooth muscle [nTPM]":"1.1","Tissue RNA - spinal cord [nTPM]":"2.0","Tissue RNA - spleen [nTPM]":"2.6","Tissue RNA - stomach 1 [nTPM]":"1.8","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"2.3","Tissue RNA - thymus [nTPM]":"1.8","Tissue RNA - thyroid gland [nTPM]":"1.1","Tissue RNA - tongue [nTPM]":"0.7","Tissue RNA - tonsil [nTPM]":"1.7","Tissue RNA - urinary bladder [nTPM]":"0.8","Tissue RNA - vagina [nTPM]":"1.0","Tissue RNA - white matter [nTPM]":"3.5","Cell RNA - A-431 [nTPM]":"1.4","Cell RNA - A549 [nTPM]":"4.4","Cell RNA - AF22 [nTPM]":"5.1","Cell RNA - AN3-CA [nTPM]":"2.1","Cell RNA - ASC diff [nTPM]":"2.9","Cell RNA - ASC TERT1 [nTPM]":"3.4","Cell RNA - BEWO [nTPM]":"5.4","Cell RNA - BJ [nTPM]":"7.9","Cell RNA - BJ hTERT+ [nTPM]":"2.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.6","Cell RNA - CACO-2 [nTPM]":"3.8","Cell RNA - CAPAN-2 [nTPM]":"2.1","Cell RNA - Daudi [nTPM]":"4.0","Cell RNA - EFO-21 [nTPM]":"8.2","Cell RNA - fHDF\/TERT166 [nTPM]":"3.0","Cell RNA - GAMG [nTPM]":"7.9","Cell RNA - HaCaT [nTPM]":"9.0","Cell RNA - HAP1 [nTPM]":"7.1","Cell RNA - HBEC3-KT [nTPM]":"2.4","Cell RNA - HBF TERT88 [nTPM]":"5.0","Cell RNA - HDLM-2 [nTPM]":"4.4","Cell RNA - HEK 293 [nTPM]":"4.2","Cell RNA - HEL [nTPM]":"8.2","Cell RNA - HeLa [nTPM]":"3.0","Cell RNA - Hep G2 [nTPM]":"2.7","Cell RNA - HHSteC [nTPM]":"2.6","Cell RNA - HL-60 [nTPM]":"8.7","Cell RNA - HMC-1 [nTPM]":"6.0","Cell RNA - HSkMC [nTPM]":"3.8","Cell RNA - hTCEpi [nTPM]":"2.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.8","Cell RNA - hTERT-HME1 [nTPM]":"3.9","Cell RNA - hTERT-RPE1 [nTPM]":"1.9","Cell RNA - HUVEC TERT2 [nTPM]":"1.2","Cell RNA - JURKAT [nTPM]":"8.2","Cell RNA - K-562 [nTPM]":"3.7","Cell RNA - Karpas-707 [nTPM]":"1.9","Cell RNA - LHCN-M2 [nTPM]":"2.3","Cell RNA - MCF7 [nTPM]":"3.5","Cell RNA - MOLT-4 [nTPM]":"10.8","Cell RNA - NB-4 [nTPM]":"1.7","Cell RNA - NTERA-2 [nTPM]":"12.1","Cell RNA - OE19 [nTPM]":"3.9","Cell RNA - PC-3 [nTPM]":"2.7","Cell RNA - REH [nTPM]":"7.4","Cell RNA - RH-30 [nTPM]":"6.0","Cell RNA - RPMI-8226 [nTPM]":"3.3","Cell RNA - RPTEC TERT1 [nTPM]":"2.4","Cell RNA - RT4 [nTPM]":"2.5","Cell RNA - SCLC-21H [nTPM]":"4.0","Cell RNA - SH-SY5Y [nTPM]":"2.6","Cell RNA - SiHa [nTPM]":"11.3","Cell RNA - SK-BR-3 [nTPM]":"4.2","Cell RNA - SK-MEL-30 [nTPM]":"4.3","Cell RNA - SuSa [nTPM]":"3.7","Cell RNA - T-47d [nTPM]":"4.1","Cell RNA - THP-1 [nTPM]":"3.1","Cell RNA - TIME [nTPM]":"15.4","Cell RNA - U-138 MG [nTPM]":"2.5","Cell RNA - U-2 OS [nTPM]":"5.2","Cell RNA - U-2197 [nTPM]":"7.4","Cell RNA - U-251 MG [nTPM]":"3.2","Cell RNA - U-266\/70 [nTPM]":"8.0","Cell RNA - U-266\/84 [nTPM]":"12.5","Cell RNA - U-698 [nTPM]":"12.1","Cell RNA - U-87 MG [nTPM]":"2.8","Cell RNA - U-937 [nTPM]":"3.4","Cell RNA - WM-115 [nTPM]":"2.6","Blood RNA - basophil [nTPM]":"5.9","Blood RNA - classical monocyte [nTPM]":"10.3","Blood RNA - eosinophil [nTPM]":"5.5","Blood RNA - gdT-cell [nTPM]":"14.0","Blood RNA - intermediate monocyte [nTPM]":"11.3","Blood RNA - MAIT T-cell [nTPM]":"12.4","Blood RNA - memory B-cell [nTPM]":"17.0","Blood RNA - memory CD4 T-cell [nTPM]":"9.2","Blood RNA - memory CD8 T-cell [nTPM]":"12.1","Blood RNA - myeloid DC [nTPM]":"14.6","Blood RNA - naive B-cell [nTPM]":"24.3","Blood RNA - naive CD4 T-cell [nTPM]":"13.9","Blood RNA - naive CD8 T-cell [nTPM]":"10.8","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"12.8","Blood RNA - non-classical monocyte [nTPM]":"9.3","Blood RNA - plasmacytoid DC [nTPM]":"11.0","Blood RNA - T-reg [nTPM]":"12.4","Blood RNA - total PBMC [nTPM]":"11.9","Brain RNA - amygdala [nTPM]":"2.5","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"2.8","Brain RNA - cerebral cortex [nTPM]":"2.9","Brain RNA - hippocampal formation [nTPM]":"2.6","Brain RNA - hypothalamus [nTPM]":"1.8","Brain RNA - medulla oblongata [nTPM]":"2.8","Brain RNA - midbrain [nTPM]":"2.1","Brain RNA - pons [nTPM]":"2.3","Brain RNA - spinal cord [nTPM]":"2.0","Brain RNA - thalamus [nTPM]":"2.3","Brain RNA - white matter [nTPM]":"3.5","Single Cell Type RNA - Adipocytes [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.5","Single Cell Type RNA - Astrocytes [nTPM]":"6.5","Single Cell Type RNA - B-cells [nTPM]":"11.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"41.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Bipolar cells [nTPM]":"8.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"22.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"66.8","Single Cell Type RNA - dendritic cells [nTPM]":"13.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"29.4","Single Cell Type RNA - Ductal cells [nTPM]":"29.8","Single Cell Type RNA - Early spermatids [nTPM]":"3.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.2","Single Cell Type RNA - Endothelial cells [nTPM]":"15.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"16.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"35.0","Single Cell Type RNA - Fibroblasts [nTPM]":"12.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.1","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"22.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"31.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.0","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.3","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"7.0","Single Cell Type RNA - Langerhans cells [nTPM]":"5.9","Single Cell Type RNA - Late spermatids [nTPM]":"4.4","Single Cell Type RNA - Leydig cells [nTPM]":"13.7","Single Cell Type RNA - Macrophages [nTPM]":"8.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"18.0","Single Cell Type RNA - Muller glia cells [nTPM]":"11.0","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"23.4","Single Cell Type RNA - Paneth cells [nTPM]":"8.6","Single Cell Type RNA - Peritubular cells [nTPM]":"13.9","Single Cell Type RNA - Plasma cells [nTPM]":"10.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"25.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.1","Single Cell Type RNA - Spermatocytes [nTPM]":"23.2","Single Cell Type RNA - Spermatogonia [nTPM]":"32.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"19.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"109.2","Single Cell Type RNA - T-cells [nTPM]":"11.0","Single Cell Type RNA - Theca cells [nTPM]":"29.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.8","Single Cell Type RNA - Urothelial cells [nTPM]":"21.1"},{"Gene":"UNC80","Gene synonym":["C2orf21","FLJ33496","KIAA1843","UNC-80"],"Ensembl":"ENSG00000144406","Gene description":"Unc-80 homolog, NALCN channel complex subunit","Uniprot":["Q8N2C7"],"Chromosome":"2","Position":"209771832-209999300","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"21.0","pituitary gland":"13.6","retina":"18.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"117.7","Excitatory neurons":"432.0","Inhibitory neurons":"354.7","Oligodendrocyte precursor cells":"290.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"0.8","prostate cancer":"0.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"AF22":"2.5","SCLC-21H":"4.0","SH-SY5Y":"2.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042472","HPA050959"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA042472":"AB_10965318","HPA050959":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.91e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"3.9","Tissue RNA - amygdala [nTPM]":"6.4","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"9.9","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"15.6","Tissue RNA - cerebral cortex [nTPM]":"21.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"6.9","Tissue RNA - hypothalamus [nTPM]":"4.9","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"6.7","Tissue RNA - midbrain [nTPM]":"1.5","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"1.0","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"13.6","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"5.8","Tissue RNA - prostate [nTPM]":"0.9","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"18.9","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"3.5","Tissue RNA - thalamus [nTPM]":"2.6","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"5.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"2.5","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.5","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"4.0","Cell RNA - SH-SY5Y [nTPM]":"2.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"6.4","Brain RNA - basal ganglia [nTPM]":"9.9","Brain RNA - cerebellum [nTPM]":"15.6","Brain RNA - cerebral cortex [nTPM]":"21.0","Brain RNA - hippocampal formation [nTPM]":"6.9","Brain RNA - hypothalamus [nTPM]":"4.9","Brain RNA - medulla oblongata [nTPM]":"6.7","Brain RNA - midbrain [nTPM]":"1.5","Brain RNA - pons [nTPM]":"5.8","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"2.6","Brain RNA - white matter [nTPM]":"5.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"49.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"117.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"66.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"31.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.7","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"432.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"52.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"354.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"10.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"26.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"290.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"75.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"7.5","Single Cell Type RNA - Spermatogonia [nTPM]":"3.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"15.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"UNC93B1","Gene synonym":["UNC93"],"Ensembl":"ENSG00000110057","Gene description":"Unc-93 homolog B1, TLR signaling regulator","Uniprot":["Q9H1C4"],"Chromosome":"11","Position":"67991100-68004982","Protein class":["Disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Adaptive immunity","Antiviral defense","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"76.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"96.2","Kupffer cells":"78.3","Macrophages":"85.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"14.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"CAPAN-2":"128.9","RPMI-8226":"368.2","SK-BR-3":"95.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038716","HPA038717","HPA042803"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA038716":"AB_2676169","HPA038717":"AB_10674836","HPA042803":"AB_2678176"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.73e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.38e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.05e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-3"},"Tissue RNA - adipose tissue [nTPM]":"18.7","Tissue RNA - adrenal gland [nTPM]":"17.7","Tissue RNA - amygdala [nTPM]":"4.9","Tissue RNA - appendix [nTPM]":"19.9","Tissue RNA - basal ganglia [nTPM]":"5.6","Tissue RNA - bone marrow [nTPM]":"19.9","Tissue RNA - breast [nTPM]":"15.4","Tissue RNA - cerebellum [nTPM]":"5.0","Tissue RNA - cerebral cortex [nTPM]":"7.5","Tissue RNA - cervix [nTPM]":"19.0","Tissue RNA - choroid plexus [nTPM]":"6.4","Tissue RNA - colon [nTPM]":"20.2","Tissue RNA - duodenum [nTPM]":"22.5","Tissue RNA - endometrium 1 [nTPM]":"7.7","Tissue RNA - epididymis [nTPM]":"0.8","Tissue RNA - esophagus [nTPM]":"20.5","Tissue RNA - fallopian tube [nTPM]":"15.7","Tissue RNA - gallbladder [nTPM]":"9.8","Tissue RNA - heart muscle [nTPM]":"7.3","Tissue RNA - hippocampal formation [nTPM]":"4.9","Tissue RNA - hypothalamus [nTPM]":"5.0","Tissue RNA - kidney [nTPM]":"16.4","Tissue RNA - liver [nTPM]":"15.3","Tissue RNA - lung [nTPM]":"29.5","Tissue RNA - lymph node [nTPM]":"29.5","Tissue RNA - medulla oblongata [nTPM]":"10.7","Tissue RNA - midbrain [nTPM]":"6.5","Tissue RNA - ovary [nTPM]":"6.2","Tissue RNA - pancreas [nTPM]":"17.1","Tissue RNA - parathyroid gland [nTPM]":"2.6","Tissue RNA - pituitary gland [nTPM]":"6.7","Tissue RNA - placenta [nTPM]":"6.4","Tissue RNA - pons [nTPM]":"8.1","Tissue RNA - prostate [nTPM]":"16.4","Tissue RNA - rectum [nTPM]":"3.1","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"27.9","Tissue RNA - seminal vesicle [nTPM]":"8.8","Tissue RNA - skeletal muscle [nTPM]":"3.5","Tissue RNA - skin 1 [nTPM]":"16.3","Tissue RNA - small intestine [nTPM]":"35.8","Tissue RNA - smooth muscle [nTPM]":"3.1","Tissue RNA - spinal cord [nTPM]":"7.9","Tissue RNA - spleen [nTPM]":"76.7","Tissue RNA - stomach 1 [nTPM]":"20.6","Tissue RNA - testis [nTPM]":"1.7","Tissue RNA - thalamus [nTPM]":"6.8","Tissue RNA - thymus [nTPM]":"3.5","Tissue RNA - thyroid gland [nTPM]":"14.8","Tissue RNA - tongue [nTPM]":"1.5","Tissue RNA - tonsil [nTPM]":"7.3","Tissue RNA - urinary bladder [nTPM]":"20.6","Tissue RNA - vagina [nTPM]":"15.0","Tissue RNA - white matter [nTPM]":"10.2","Cell RNA - A-431 [nTPM]":"18.9","Cell RNA - A549 [nTPM]":"34.1","Cell RNA - AF22 [nTPM]":"2.5","Cell RNA - AN3-CA [nTPM]":"13.8","Cell RNA - ASC diff [nTPM]":"7.2","Cell RNA - ASC TERT1 [nTPM]":"2.7","Cell RNA - BEWO [nTPM]":"28.2","Cell RNA - BJ [nTPM]":"8.3","Cell RNA - BJ hTERT+ [nTPM]":"7.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.8","Cell RNA - CACO-2 [nTPM]":"2.8","Cell RNA - CAPAN-2 [nTPM]":"128.9","Cell RNA - Daudi [nTPM]":"40.9","Cell RNA - EFO-21 [nTPM]":"30.8","Cell RNA - fHDF\/TERT166 [nTPM]":"4.0","Cell RNA - GAMG [nTPM]":"11.0","Cell RNA - HaCaT [nTPM]":"44.9","Cell RNA - HAP1 [nTPM]":"1.0","Cell RNA - HBEC3-KT [nTPM]":"7.0","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"14.1","Cell RNA - HEK 293 [nTPM]":"9.3","Cell RNA - HEL [nTPM]":"4.2","Cell RNA - HeLa [nTPM]":"11.1","Cell RNA - Hep G2 [nTPM]":"6.4","Cell RNA - HHSteC [nTPM]":"11.2","Cell RNA - HL-60 [nTPM]":"30.0","Cell RNA - HMC-1 [nTPM]":"22.7","Cell RNA - HSkMC [nTPM]":"6.0","Cell RNA - hTCEpi [nTPM]":"7.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.8","Cell RNA - hTERT-HME1 [nTPM]":"1.5","Cell RNA - hTERT-RPE1 [nTPM]":"5.0","Cell RNA - HUVEC TERT2 [nTPM]":"2.6","Cell RNA - JURKAT [nTPM]":"6.4","Cell RNA - K-562 [nTPM]":"3.0","Cell RNA - Karpas-707 [nTPM]":"19.3","Cell RNA - LHCN-M2 [nTPM]":"2.0","Cell RNA - MCF7 [nTPM]":"18.7","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"23.9","Cell RNA - NTERA-2 [nTPM]":"6.2","Cell RNA - OE19 [nTPM]":"46.8","Cell RNA - PC-3 [nTPM]":"16.7","Cell RNA - REH [nTPM]":"24.5","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"368.2","Cell RNA - RPTEC TERT1 [nTPM]":"11.8","Cell RNA - RT4 [nTPM]":"10.7","Cell RNA - SCLC-21H [nTPM]":"3.9","Cell RNA - SH-SY5Y [nTPM]":"5.5","Cell RNA - SiHa [nTPM]":"14.0","Cell RNA - SK-BR-3 [nTPM]":"95.6","Cell RNA - SK-MEL-30 [nTPM]":"19.3","Cell RNA - SuSa [nTPM]":"1.0","Cell RNA - T-47d [nTPM]":"35.4","Cell RNA - THP-1 [nTPM]":"39.0","Cell RNA - TIME [nTPM]":"9.2","Cell RNA - U-138 MG [nTPM]":"8.6","Cell RNA - U-2 OS [nTPM]":"12.2","Cell RNA - U-2197 [nTPM]":"12.8","Cell RNA - U-251 MG [nTPM]":"0.8","Cell RNA - U-266\/70 [nTPM]":"13.2","Cell RNA - U-266\/84 [nTPM]":"18.8","Cell RNA - U-698 [nTPM]":"7.0","Cell RNA - U-87 MG [nTPM]":"16.0","Cell RNA - U-937 [nTPM]":"30.7","Cell RNA - WM-115 [nTPM]":"10.5","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"3.8","Blood RNA - eosinophil [nTPM]":"6.6","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"7.2","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"5.1","Blood RNA - naive B-cell [nTPM]":"2.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"3.2","Blood RNA - NK-cell [nTPM]":"2.1","Blood RNA - non-classical monocyte [nTPM]":"7.7","Blood RNA - plasmacytoid DC [nTPM]":"14.8","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"4.9","Brain RNA - basal ganglia [nTPM]":"5.6","Brain RNA - cerebellum [nTPM]":"5.0","Brain RNA - cerebral cortex [nTPM]":"7.5","Brain RNA - hippocampal formation [nTPM]":"4.9","Brain RNA - hypothalamus [nTPM]":"5.0","Brain RNA - medulla oblongata [nTPM]":"10.7","Brain RNA - midbrain [nTPM]":"6.5","Brain RNA - pons [nTPM]":"8.1","Brain RNA - spinal cord [nTPM]":"7.9","Brain RNA - thalamus [nTPM]":"6.8","Brain RNA - white matter [nTPM]":"10.2","Single Cell Type RNA - Adipocytes [nTPM]":"12.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.1","Single Cell Type RNA - Astrocytes [nTPM]":"4.6","Single Cell Type RNA - B-cells [nTPM]":"45.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"40.0","Single Cell Type RNA - Club cells [nTPM]":"21.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.3","Single Cell Type RNA - dendritic cells [nTPM]":"63.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"36.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"32.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.9","Single Cell Type RNA - Endothelial cells [nTPM]":"10.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"3.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"47.8","Single Cell Type RNA - Fibroblasts [nTPM]":"8.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.2","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"9.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.0","Single Cell Type RNA - Hepatocytes [nTPM]":"5.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"96.2","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.2","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"78.3","Single Cell Type RNA - Langerhans cells [nTPM]":"28.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"4.4","Single Cell Type RNA - Macrophages [nTPM]":"85.3","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"57.5","Single Cell Type RNA - Muller glia cells [nTPM]":"4.7","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"49.7","Single Cell Type RNA - Paneth cells [nTPM]":"25.6","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"33.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"27.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"31.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"57.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"1.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.3","Single Cell Type RNA - T-cells [nTPM]":"10.5","Single Cell Type RNA - Theca cells [nTPM]":"2.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.1","Single Cell Type RNA - Urothelial cells [nTPM]":"37.7"},{"Gene":"UNG","Gene synonym":["DGU","HIGM4","UDG","UNG1","UNG2"],"Ensembl":"ENSG00000076248","Gene description":"Uracil DNA glycosylase","Uniprot":["P13051"],"Chromosome":"12","Position":"109097597-109110992","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Host-virus interaction"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"64.9","Spermatogonia":"74.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011605"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB011605":"AB_778737"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.40e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.06e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-2"},"Tissue RNA - adipose tissue [nTPM]":"19.8","Tissue RNA - adrenal gland [nTPM]":"56.7","Tissue RNA - amygdala [nTPM]":"32.4","Tissue RNA - appendix [nTPM]":"14.7","Tissue RNA - basal ganglia [nTPM]":"32.4","Tissue RNA - bone marrow [nTPM]":"16.0","Tissue RNA - breast [nTPM]":"23.1","Tissue RNA - cerebellum [nTPM]":"30.1","Tissue RNA - cerebral cortex [nTPM]":"34.8","Tissue RNA - cervix [nTPM]":"16.6","Tissue RNA - choroid plexus [nTPM]":"27.7","Tissue RNA - colon [nTPM]":"28.0","Tissue RNA - duodenum [nTPM]":"17.1","Tissue RNA - endometrium 1 [nTPM]":"14.5","Tissue RNA - epididymis [nTPM]":"12.7","Tissue RNA - esophagus [nTPM]":"29.7","Tissue RNA - fallopian tube [nTPM]":"15.6","Tissue RNA - gallbladder [nTPM]":"10.4","Tissue RNA - heart muscle [nTPM]":"21.1","Tissue RNA - hippocampal formation [nTPM]":"29.2","Tissue RNA - hypothalamus [nTPM]":"34.9","Tissue RNA - kidney [nTPM]":"27.5","Tissue RNA - liver [nTPM]":"32.2","Tissue RNA - lung [nTPM]":"9.6","Tissue RNA - lymph node [nTPM]":"18.0","Tissue RNA - medulla oblongata [nTPM]":"32.2","Tissue RNA - midbrain [nTPM]":"31.4","Tissue RNA - ovary [nTPM]":"15.7","Tissue RNA - pancreas [nTPM]":"12.4","Tissue RNA - parathyroid gland [nTPM]":"33.2","Tissue RNA - pituitary gland [nTPM]":"10.9","Tissue RNA - placenta [nTPM]":"17.8","Tissue RNA - pons [nTPM]":"34.1","Tissue RNA - prostate [nTPM]":"13.6","Tissue RNA - rectum [nTPM]":"29.3","Tissue RNA - retina [nTPM]":"6.8","Tissue RNA - salivary gland [nTPM]":"17.7","Tissue RNA - seminal vesicle [nTPM]":"17.6","Tissue RNA - skeletal muscle [nTPM]":"43.0","Tissue RNA - skin 1 [nTPM]":"32.7","Tissue RNA - small intestine [nTPM]":"18.8","Tissue RNA - smooth muscle [nTPM]":"14.5","Tissue RNA - spinal cord [nTPM]":"31.6","Tissue RNA - spleen [nTPM]":"16.1","Tissue RNA - stomach 1 [nTPM]":"17.7","Tissue RNA - testis [nTPM]":"24.3","Tissue RNA - thalamus [nTPM]":"33.5","Tissue RNA - thymus [nTPM]":"22.8","Tissue RNA - thyroid gland [nTPM]":"22.2","Tissue RNA - tongue [nTPM]":"33.5","Tissue RNA - tonsil [nTPM]":"27.0","Tissue RNA - urinary bladder [nTPM]":"13.5","Tissue RNA - vagina [nTPM]":"20.1","Tissue RNA - white matter [nTPM]":"30.8","Cell RNA - A-431 [nTPM]":"77.1","Cell RNA - A549 [nTPM]":"77.5","Cell RNA - AF22 [nTPM]":"72.8","Cell RNA - AN3-CA [nTPM]":"66.6","Cell RNA - ASC diff [nTPM]":"118.6","Cell RNA - ASC TERT1 [nTPM]":"33.8","Cell RNA - BEWO [nTPM]":"69.5","Cell RNA - BJ [nTPM]":"44.4","Cell RNA - BJ hTERT+ [nTPM]":"30.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"68.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"52.3","Cell RNA - CACO-2 [nTPM]":"61.7","Cell RNA - CAPAN-2 [nTPM]":"51.6","Cell RNA - Daudi [nTPM]":"100.3","Cell RNA - EFO-21 [nTPM]":"65.1","Cell RNA - fHDF\/TERT166 [nTPM]":"40.2","Cell RNA - GAMG [nTPM]":"35.9","Cell RNA - HaCaT [nTPM]":"47.6","Cell RNA - HAP1 [nTPM]":"81.4","Cell RNA - HBEC3-KT [nTPM]":"46.0","Cell RNA - HBF TERT88 [nTPM]":"66.4","Cell RNA - HDLM-2 [nTPM]":"85.6","Cell RNA - HEK 293 [nTPM]":"150.9","Cell RNA - HEL [nTPM]":"98.1","Cell RNA - HeLa [nTPM]":"41.1","Cell RNA - Hep G2 [nTPM]":"105.5","Cell RNA - HHSteC [nTPM]":"17.7","Cell RNA - HL-60 [nTPM]":"147.6","Cell RNA - HMC-1 [nTPM]":"58.2","Cell RNA - HSkMC [nTPM]":"30.7","Cell RNA - hTCEpi [nTPM]":"41.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"33.0","Cell RNA - hTERT-HME1 [nTPM]":"18.3","Cell RNA - hTERT-RPE1 [nTPM]":"54.6","Cell RNA - HUVEC TERT2 [nTPM]":"50.4","Cell RNA - JURKAT [nTPM]":"117.8","Cell RNA - K-562 [nTPM]":"80.9","Cell RNA - Karpas-707 [nTPM]":"32.5","Cell RNA - LHCN-M2 [nTPM]":"47.0","Cell RNA - MCF7 [nTPM]":"96.2","Cell RNA - MOLT-4 [nTPM]":"136.8","Cell RNA - NB-4 [nTPM]":"173.6","Cell RNA - NTERA-2 [nTPM]":"130.0","Cell RNA - OE19 [nTPM]":"124.2","Cell RNA - PC-3 [nTPM]":"117.7","Cell RNA - REH [nTPM]":"123.9","Cell RNA - RH-30 [nTPM]":"109.8","Cell RNA - RPMI-8226 [nTPM]":"85.9","Cell RNA - RPTEC TERT1 [nTPM]":"43.4","Cell RNA - RT4 [nTPM]":"95.6","Cell RNA - SCLC-21H [nTPM]":"103.3","Cell RNA - SH-SY5Y [nTPM]":"57.4","Cell RNA - SiHa [nTPM]":"79.6","Cell RNA - SK-BR-3 [nTPM]":"67.8","Cell RNA - SK-MEL-30 [nTPM]":"39.5","Cell RNA - SuSa [nTPM]":"94.2","Cell RNA - T-47d [nTPM]":"126.2","Cell RNA - THP-1 [nTPM]":"68.2","Cell RNA - TIME [nTPM]":"26.0","Cell RNA - U-138 MG [nTPM]":"59.1","Cell RNA - U-2 OS [nTPM]":"52.7","Cell RNA - U-2197 [nTPM]":"39.3","Cell RNA - U-251 MG [nTPM]":"62.5","Cell RNA - U-266\/70 [nTPM]":"62.6","Cell RNA - U-266\/84 [nTPM]":"145.0","Cell RNA - U-698 [nTPM]":"190.5","Cell RNA - U-87 MG [nTPM]":"44.8","Cell RNA - U-937 [nTPM]":"97.7","Cell RNA - WM-115 [nTPM]":"73.8","Blood RNA - basophil [nTPM]":"12.9","Blood RNA - classical monocyte [nTPM]":"2.7","Blood RNA - eosinophil [nTPM]":"5.0","Blood RNA - gdT-cell [nTPM]":"22.4","Blood RNA - intermediate monocyte [nTPM]":"5.3","Blood RNA - MAIT T-cell [nTPM]":"31.6","Blood RNA - memory B-cell [nTPM]":"16.0","Blood RNA - memory CD4 T-cell [nTPM]":"25.5","Blood RNA - memory CD8 T-cell [nTPM]":"25.6","Blood RNA - myeloid DC [nTPM]":"6.8","Blood RNA - naive B-cell [nTPM]":"17.2","Blood RNA - naive CD4 T-cell [nTPM]":"16.4","Blood RNA - naive CD8 T-cell [nTPM]":"18.4","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"16.5","Blood RNA - non-classical monocyte [nTPM]":"5.5","Blood RNA - plasmacytoid DC [nTPM]":"4.9","Blood RNA - T-reg [nTPM]":"25.5","Blood RNA - total PBMC [nTPM]":"14.4","Brain RNA - amygdala [nTPM]":"32.4","Brain RNA - basal ganglia [nTPM]":"32.4","Brain RNA - cerebellum [nTPM]":"30.1","Brain RNA - cerebral cortex [nTPM]":"34.8","Brain RNA - hippocampal formation [nTPM]":"29.2","Brain RNA - hypothalamus [nTPM]":"34.9","Brain RNA - medulla oblongata [nTPM]":"32.2","Brain RNA - midbrain [nTPM]":"31.4","Brain RNA - pons [nTPM]":"34.1","Brain RNA - spinal cord [nTPM]":"31.6","Brain RNA - thalamus [nTPM]":"33.5","Brain RNA - white matter [nTPM]":"30.8","Single Cell Type RNA - Adipocytes [nTPM]":"26.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"16.0","Single Cell Type RNA - B-cells [nTPM]":"9.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.0","Single Cell Type RNA - Bipolar cells [nTPM]":"2.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"5.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"42.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"64.9","Single Cell Type RNA - dendritic cells [nTPM]":"12.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"14.4","Single Cell Type RNA - Early spermatids [nTPM]":"3.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.0","Single Cell Type RNA - Endothelial cells [nTPM]":"17.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"32.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"38.1","Single Cell Type RNA - Fibroblasts [nTPM]":"12.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.9","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"24.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.3","Single Cell Type RNA - Hepatocytes [nTPM]":"20.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.3","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.4","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"3.8","Single Cell Type RNA - Langerhans cells [nTPM]":"5.4","Single Cell Type RNA - Late spermatids [nTPM]":"4.2","Single Cell Type RNA - Leydig cells [nTPM]":"14.0","Single Cell Type RNA - Macrophages [nTPM]":"5.5","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"3.8","Single Cell Type RNA - Muller glia cells [nTPM]":"15.8","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.0","Single Cell Type RNA - Paneth cells [nTPM]":"10.3","Single Cell Type RNA - Peritubular cells [nTPM]":"14.7","Single Cell Type RNA - Plasma cells [nTPM]":"16.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"20.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.5","Single Cell Type RNA - Spermatocytes [nTPM]":"21.9","Single Cell Type RNA - Spermatogonia [nTPM]":"74.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"37.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.4","Single Cell Type RNA - T-cells [nTPM]":"15.3","Single Cell Type RNA - Theca cells [nTPM]":"25.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"40.4","Single Cell Type RNA - Urothelial cells [nTPM]":"9.7"},{"Gene":"UPB1","Gene synonym":["BUP1"],"Ensembl":"ENSG00000100024","Gene description":"Beta-ureidopropionase 1","Uniprot":["Q9UBR1"],"Chromosome":"22","Position":"24494107-24528390","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"liver":"216.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Hepatocytes":"146.5","Proximal tubular cells":"68.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"liver cancer":"25.4"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"1.8"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"14","RNA blood cell specific nTPM":{"basophil":"2.1","neutrophil":"2.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"14","RNA blood lineage specific nTPM":{"granulocytes":"2.1"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"CACO-2":"3.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000728","HPA076321"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1400000","Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA000728":"AB_1080471","HPA076321":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.30e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"2.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"1.8","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"1.2","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"1.9","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"25.7","Tissue RNA - liver [nTPM]":"216.0","Tissue RNA - lung [nTPM]":"0.8","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.4","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"1.1","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.8","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"3.0","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"0.6","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"3.3","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"2.1","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"2.1","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"1.8","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"4.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.6","Single Cell Type RNA - Endothelial cells [nTPM]":"1.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"5.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"146.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"5.1","Single Cell Type RNA - Langerhans cells [nTPM]":"2.7","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"21.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"68.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.7","Single Cell Type RNA - Spermatocytes [nTPM]":"12.8","Single Cell Type RNA - Spermatogonia [nTPM]":"6.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"1.1"},{"Gene":"UPK3A","Gene synonym":["UPK3"],"Ensembl":"ENSG00000100373","Gene description":"Uroplakin 3A","Uniprot":["O75631"],"Chromosome":"22","Position":"45284949-45295874","Protein class":["Disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"prostate":"21.3","skeletal muscle":"35.0","urinary bladder":"48.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"15.0","monocytes":"22.6","Prostatic glandular cells":"54.1","Proximal enterocytes":"29.8","Urothelial cells":"24.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"prostate cancer":"35.3","urothelial cancer":"78.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"86.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"16","RNA blood lineage specific nTPM":{"dendritic cells":"86.6","monocytes":"32.0"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Hep G2":"29.9","RT4":"48.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018407","HPA018415"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nuclear membrane","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 35: Glandular cells - Unknown function","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA018407":"AB_1858641","HPA018415":"AB_1858640"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"1.5","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"1.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.9","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.9","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"4.9","Tissue RNA - pituitary gland [nTPM]":"0.7","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"21.3","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"2.8","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"35.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"1.3","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"1.1","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.7","Tissue RNA - thyroid gland [nTPM]":"2.3","Tissue RNA - tongue [nTPM]":"4.5","Tissue RNA - tonsil [nTPM]":"0.8","Tissue RNA - urinary bladder [nTPM]":"48.0","Tissue RNA - vagina [nTPM]":"1.1","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"1.2","Cell RNA - CAPAN-2 [nTPM]":"0.9","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"29.9","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"4.7","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"8.5","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"4.6","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"48.9","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.8","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"5.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"2.5","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"21.2","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"25.8","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"1.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"86.6","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"3.6","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"32.0","Blood RNA - plasmacytoid DC [nTPM]":"32.9","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"7.4","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"1.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"4.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.8","Single Cell Type RNA - Langerhans cells [nTPM]":"8.7","Single Cell Type RNA - Late spermatids [nTPM]":"1.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"6.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"22.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"9.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"54.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"29.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.4","Single Cell Type RNA - Urothelial cells [nTPM]":"24.5"},{"Gene":"UQCRC2","Gene synonym":["QCR2","UQCR2"],"Ensembl":"ENSG00000140740","Gene description":"Ubiquinol-cytochrome c reductase core protein 2","Uniprot":["P22695"],"Chromosome":"16","Position":"21953288-21983660","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"722.2","tongue":"933.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"556.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007998","HPA019146"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"180000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA007998":"AB_1858648","HPA019146":"AB_1858649"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.58e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.78e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-2"},"Tissue RNA - adipose tissue [nTPM]":"158.8","Tissue RNA - adrenal gland [nTPM]":"117.7","Tissue RNA - amygdala [nTPM]":"69.0","Tissue RNA - appendix [nTPM]":"103.1","Tissue RNA - basal ganglia [nTPM]":"71.2","Tissue RNA - bone marrow [nTPM]":"127.7","Tissue RNA - breast [nTPM]":"108.4","Tissue RNA - cerebellum [nTPM]":"75.5","Tissue RNA - cerebral cortex [nTPM]":"90.0","Tissue RNA - cervix [nTPM]":"90.8","Tissue RNA - choroid plexus [nTPM]":"113.9","Tissue RNA - colon [nTPM]":"259.8","Tissue RNA - duodenum [nTPM]":"292.5","Tissue RNA - endometrium 1 [nTPM]":"98.2","Tissue RNA - epididymis [nTPM]":"72.7","Tissue RNA - esophagus [nTPM]":"157.4","Tissue RNA - fallopian tube [nTPM]":"109.7","Tissue RNA - gallbladder [nTPM]":"99.5","Tissue RNA - heart muscle [nTPM]":"559.4","Tissue RNA - hippocampal formation [nTPM]":"72.4","Tissue RNA - hypothalamus [nTPM]":"73.7","Tissue RNA - kidney [nTPM]":"240.0","Tissue RNA - liver [nTPM]":"245.1","Tissue RNA - lung [nTPM]":"75.4","Tissue RNA - lymph node [nTPM]":"120.0","Tissue RNA - medulla oblongata [nTPM]":"74.1","Tissue RNA - midbrain [nTPM]":"69.5","Tissue RNA - ovary [nTPM]":"114.5","Tissue RNA - pancreas [nTPM]":"89.7","Tissue RNA - parathyroid gland [nTPM]":"257.2","Tissue RNA - pituitary gland [nTPM]":"39.8","Tissue RNA - placenta [nTPM]":"96.5","Tissue RNA - pons [nTPM]":"72.7","Tissue RNA - prostate [nTPM]":"95.6","Tissue RNA - rectum [nTPM]":"262.8","Tissue RNA - retina [nTPM]":"142.3","Tissue RNA - salivary gland [nTPM]":"133.8","Tissue RNA - seminal vesicle [nTPM]":"104.3","Tissue RNA - skeletal muscle [nTPM]":"722.2","Tissue RNA - skin 1 [nTPM]":"85.4","Tissue RNA - small intestine [nTPM]":"233.6","Tissue RNA - smooth muscle [nTPM]":"121.2","Tissue RNA - spinal cord [nTPM]":"65.8","Tissue RNA - spleen [nTPM]":"80.9","Tissue RNA - stomach 1 [nTPM]":"153.2","Tissue RNA - testis [nTPM]":"55.8","Tissue RNA - thalamus [nTPM]":"76.5","Tissue RNA - thymus [nTPM]":"131.3","Tissue RNA - thyroid gland [nTPM]":"107.9","Tissue RNA - tongue [nTPM]":"933.2","Tissue RNA - tonsil [nTPM]":"149.3","Tissue RNA - urinary bladder [nTPM]":"153.6","Tissue RNA - vagina [nTPM]":"59.8","Tissue RNA - white matter [nTPM]":"73.3","Cell RNA - A-431 [nTPM]":"173.9","Cell RNA - A549 [nTPM]":"193.1","Cell RNA - AF22 [nTPM]":"116.5","Cell RNA - AN3-CA [nTPM]":"66.4","Cell RNA - ASC diff [nTPM]":"154.3","Cell RNA - ASC TERT1 [nTPM]":"186.8","Cell RNA - BEWO [nTPM]":"169.1","Cell RNA - BJ [nTPM]":"163.8","Cell RNA - BJ hTERT+ [nTPM]":"160.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"177.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"174.5","Cell RNA - CACO-2 [nTPM]":"347.9","Cell RNA - CAPAN-2 [nTPM]":"177.7","Cell RNA - Daudi [nTPM]":"338.9","Cell RNA - EFO-21 [nTPM]":"144.3","Cell RNA - fHDF\/TERT166 [nTPM]":"170.4","Cell RNA - GAMG [nTPM]":"129.8","Cell RNA - HaCaT [nTPM]":"324.6","Cell RNA - HAP1 [nTPM]":"222.3","Cell RNA - HBEC3-KT [nTPM]":"212.7","Cell RNA - HBF TERT88 [nTPM]":"193.7","Cell RNA - HDLM-2 [nTPM]":"151.4","Cell RNA - HEK 293 [nTPM]":"178.4","Cell RNA - HEL [nTPM]":"185.9","Cell RNA - HeLa [nTPM]":"166.1","Cell RNA - Hep G2 [nTPM]":"494.3","Cell RNA - HHSteC [nTPM]":"164.6","Cell RNA - HL-60 [nTPM]":"249.1","Cell RNA - HMC-1 [nTPM]":"501.2","Cell RNA - HSkMC [nTPM]":"232.3","Cell RNA - hTCEpi [nTPM]":"229.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"130.3","Cell RNA - hTERT-HME1 [nTPM]":"186.2","Cell RNA - hTERT-RPE1 [nTPM]":"169.4","Cell RNA - HUVEC TERT2 [nTPM]":"248.1","Cell RNA - JURKAT [nTPM]":"224.1","Cell RNA - K-562 [nTPM]":"217.9","Cell RNA - Karpas-707 [nTPM]":"159.1","Cell RNA - LHCN-M2 [nTPM]":"177.2","Cell RNA - MCF7 [nTPM]":"230.6","Cell RNA - MOLT-4 [nTPM]":"288.6","Cell RNA - NB-4 [nTPM]":"175.0","Cell RNA - NTERA-2 [nTPM]":"124.6","Cell RNA - OE19 [nTPM]":"261.1","Cell RNA - PC-3 [nTPM]":"148.8","Cell RNA - REH [nTPM]":"310.9","Cell RNA - RH-30 [nTPM]":"263.6","Cell RNA - RPMI-8226 [nTPM]":"390.0","Cell RNA - RPTEC TERT1 [nTPM]":"285.8","Cell RNA - RT4 [nTPM]":"214.6","Cell RNA - SCLC-21H [nTPM]":"154.4","Cell RNA - SH-SY5Y [nTPM]":"114.9","Cell RNA - SiHa [nTPM]":"237.2","Cell RNA - SK-BR-3 [nTPM]":"318.6","Cell RNA - SK-MEL-30 [nTPM]":"190.3","Cell RNA - SuSa [nTPM]":"151.6","Cell RNA - T-47d [nTPM]":"354.4","Cell RNA - THP-1 [nTPM]":"264.1","Cell RNA - TIME [nTPM]":"179.3","Cell RNA - U-138 MG [nTPM]":"103.3","Cell RNA - U-2 OS [nTPM]":"98.1","Cell RNA - U-2197 [nTPM]":"104.0","Cell RNA - U-251 MG [nTPM]":"148.0","Cell RNA - U-266\/70 [nTPM]":"126.3","Cell RNA - U-266\/84 [nTPM]":"87.2","Cell RNA - U-698 [nTPM]":"302.7","Cell RNA - U-87 MG [nTPM]":"188.7","Cell RNA - U-937 [nTPM]":"239.8","Cell RNA - WM-115 [nTPM]":"126.4","Blood RNA - basophil [nTPM]":"80.1","Blood RNA - classical monocyte [nTPM]":"128.7","Blood RNA - eosinophil [nTPM]":"71.4","Blood RNA - gdT-cell [nTPM]":"80.0","Blood RNA - intermediate monocyte [nTPM]":"147.8","Blood RNA - MAIT T-cell [nTPM]":"103.3","Blood RNA - memory B-cell [nTPM]":"96.0","Blood RNA - memory CD4 T-cell [nTPM]":"98.3","Blood RNA - memory CD8 T-cell [nTPM]":"89.3","Blood RNA - myeloid DC [nTPM]":"153.9","Blood RNA - naive B-cell [nTPM]":"77.9","Blood RNA - naive CD4 T-cell [nTPM]":"106.8","Blood RNA - naive CD8 T-cell [nTPM]":"97.6","Blood RNA - neutrophil [nTPM]":"45.9","Blood RNA - NK-cell [nTPM]":"101.8","Blood RNA - non-classical monocyte [nTPM]":"148.1","Blood RNA - plasmacytoid DC [nTPM]":"67.6","Blood RNA - T-reg [nTPM]":"134.8","Blood RNA - total PBMC [nTPM]":"157.3","Brain RNA - amygdala [nTPM]":"69.0","Brain RNA - basal ganglia [nTPM]":"71.2","Brain RNA - cerebellum [nTPM]":"75.5","Brain RNA - cerebral cortex [nTPM]":"90.0","Brain RNA - hippocampal formation [nTPM]":"72.4","Brain RNA - hypothalamus [nTPM]":"73.7","Brain RNA - medulla oblongata [nTPM]":"74.1","Brain RNA - midbrain [nTPM]":"69.5","Brain RNA - pons [nTPM]":"72.7","Brain RNA - spinal cord [nTPM]":"65.8","Brain RNA - thalamus [nTPM]":"76.5","Brain RNA - white matter [nTPM]":"73.3","Single Cell Type RNA - Adipocytes [nTPM]":"105.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"64.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"52.5","Single Cell Type RNA - Astrocytes [nTPM]":"81.9","Single Cell Type RNA - B-cells [nTPM]":"81.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"90.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"190.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"444.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"74.6","Single Cell Type RNA - Bipolar cells [nTPM]":"109.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"91.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"79.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"556.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"84.4","Single Cell Type RNA - Club cells [nTPM]":"194.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"71.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"87.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"238.3","Single Cell Type RNA - dendritic cells [nTPM]":"82.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"233.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"455.9","Single Cell Type RNA - Ductal cells [nTPM]":"124.5","Single Cell Type RNA - Early spermatids [nTPM]":"88.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"72.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"55.7","Single Cell Type RNA - Endothelial cells [nTPM]":"91.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"113.8","Single Cell Type RNA - Erythroid cells [nTPM]":"92.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"65.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"109.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"157.6","Single Cell Type RNA - Fibroblasts [nTPM]":"89.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"144.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"65.8","Single Cell Type RNA - granulocytes [nTPM]":"92.6","Single Cell Type RNA - Granulosa cells [nTPM]":"99.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"84.3","Single Cell Type RNA - Hepatocytes [nTPM]":"122.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"195.5","Single Cell Type RNA - Horizontal cells [nTPM]":"69.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"74.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"224.4","Single Cell Type RNA - Ionocytes [nTPM]":"238.0","Single Cell Type RNA - Kupffer cells [nTPM]":"145.1","Single Cell Type RNA - Langerhans cells [nTPM]":"100.6","Single Cell Type RNA - Late spermatids [nTPM]":"89.9","Single Cell Type RNA - Leydig cells [nTPM]":"68.3","Single Cell Type RNA - Macrophages [nTPM]":"104.6","Single Cell Type RNA - Melanocytes [nTPM]":"131.6","Single Cell Type RNA - Microglial cells [nTPM]":"27.2","Single Cell Type RNA - monocytes [nTPM]":"162.1","Single Cell Type RNA - Muller glia cells [nTPM]":"108.0","Single Cell Type RNA - NK-cells [nTPM]":"91.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"60.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"50.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"97.2","Single Cell Type RNA - Paneth cells [nTPM]":"214.0","Single Cell Type RNA - Peritubular cells [nTPM]":"97.0","Single Cell Type RNA - Plasma cells [nTPM]":"72.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"114.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"378.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"306.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"110.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"152.6","Single Cell Type RNA - Sertoli cells [nTPM]":"78.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"94.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"109.5","Single Cell Type RNA - Spermatocytes [nTPM]":"68.9","Single Cell Type RNA - Spermatogonia [nTPM]":"56.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"132.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"88.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"278.3","Single Cell Type RNA - T-cells [nTPM]":"91.3","Single Cell Type RNA - Theca cells [nTPM]":"170.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"358.7","Single Cell Type RNA - Urothelial cells [nTPM]":"204.3"},{"Gene":"UQCRFS1","Gene synonym":["RIP1","RIS1","RISP","UQCR5"],"Ensembl":"ENSG00000169021","Gene description":"Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1","Uniprot":["P47985"],"Chromosome":"19","Position":"29205320-29213151","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"231.6","tongue":"285.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"1474.9","Distal tubular cells":"1035.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041863","HPA050339"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA041863":"AB_10794638","HPA050339":"AB_2681095"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.29e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.84e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.92e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Tissue RNA - adipose tissue [nTPM]":"28.7","Tissue RNA - adrenal gland [nTPM]":"50.1","Tissue RNA - amygdala [nTPM]":"25.6","Tissue RNA - appendix [nTPM]":"17.4","Tissue RNA - basal ganglia [nTPM]":"26.7","Tissue RNA - bone marrow [nTPM]":"52.8","Tissue RNA - breast [nTPM]":"24.7","Tissue RNA - cerebellum [nTPM]":"29.4","Tissue RNA - cerebral cortex [nTPM]":"31.1","Tissue RNA - cervix [nTPM]":"18.3","Tissue RNA - choroid plexus [nTPM]":"33.6","Tissue RNA - colon [nTPM]":"49.0","Tissue RNA - duodenum [nTPM]":"43.2","Tissue RNA - endometrium 1 [nTPM]":"19.2","Tissue RNA - epididymis [nTPM]":"23.1","Tissue RNA - esophagus [nTPM]":"33.2","Tissue RNA - fallopian tube [nTPM]":"19.3","Tissue RNA - gallbladder [nTPM]":"13.2","Tissue RNA - heart muscle [nTPM]":"138.3","Tissue RNA - hippocampal formation [nTPM]":"27.2","Tissue RNA - hypothalamus [nTPM]":"28.4","Tissue RNA - kidney [nTPM]":"62.5","Tissue RNA - liver [nTPM]":"50.9","Tissue RNA - lung [nTPM]":"17.6","Tissue RNA - lymph node [nTPM]":"17.2","Tissue RNA - medulla oblongata [nTPM]":"27.0","Tissue RNA - midbrain [nTPM]":"27.4","Tissue RNA - ovary [nTPM]":"15.4","Tissue RNA - pancreas [nTPM]":"29.4","Tissue RNA - parathyroid gland [nTPM]":"47.3","Tissue RNA - pituitary gland [nTPM]":"19.9","Tissue RNA - placenta [nTPM]":"17.3","Tissue RNA - pons [nTPM]":"26.1","Tissue RNA - prostate [nTPM]":"18.8","Tissue RNA - rectum [nTPM]":"52.6","Tissue RNA - retina [nTPM]":"26.6","Tissue RNA - salivary gland [nTPM]":"26.7","Tissue RNA - seminal vesicle [nTPM]":"21.9","Tissue RNA - skeletal muscle [nTPM]":"231.6","Tissue RNA - skin 1 [nTPM]":"27.9","Tissue RNA - small intestine [nTPM]":"34.0","Tissue RNA - smooth muscle [nTPM]":"24.8","Tissue RNA - spinal cord [nTPM]":"26.4","Tissue RNA - spleen [nTPM]":"21.1","Tissue RNA - stomach 1 [nTPM]":"39.3","Tissue RNA - testis [nTPM]":"25.9","Tissue RNA - thalamus [nTPM]":"29.3","Tissue RNA - thymus [nTPM]":"26.0","Tissue RNA - thyroid gland [nTPM]":"16.8","Tissue RNA - tongue [nTPM]":"285.9","Tissue RNA - tonsil [nTPM]":"25.9","Tissue RNA - urinary bladder [nTPM]":"25.7","Tissue RNA - vagina [nTPM]":"20.3","Tissue RNA - white matter [nTPM]":"26.0","Cell RNA - A-431 [nTPM]":"63.0","Cell RNA - A549 [nTPM]":"103.7","Cell RNA - AF22 [nTPM]":"37.7","Cell RNA - AN3-CA [nTPM]":"34.1","Cell RNA - ASC diff [nTPM]":"60.6","Cell RNA - ASC TERT1 [nTPM]":"45.9","Cell RNA - BEWO [nTPM]":"41.8","Cell RNA - BJ [nTPM]":"47.8","Cell RNA - BJ hTERT+ [nTPM]":"49.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"64.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"71.1","Cell RNA - CACO-2 [nTPM]":"63.3","Cell RNA - CAPAN-2 [nTPM]":"37.7","Cell RNA - Daudi [nTPM]":"56.7","Cell RNA - EFO-21 [nTPM]":"49.2","Cell RNA - fHDF\/TERT166 [nTPM]":"54.4","Cell RNA - GAMG [nTPM]":"52.7","Cell RNA - HaCaT [nTPM]":"64.8","Cell RNA - HAP1 [nTPM]":"83.4","Cell RNA - HBEC3-KT [nTPM]":"56.9","Cell RNA - HBF TERT88 [nTPM]":"77.6","Cell RNA - HDLM-2 [nTPM]":"38.7","Cell RNA - HEK 293 [nTPM]":"83.2","Cell RNA - HEL [nTPM]":"80.2","Cell RNA - HeLa [nTPM]":"39.2","Cell RNA - Hep G2 [nTPM]":"58.1","Cell RNA - HHSteC [nTPM]":"51.3","Cell RNA - HL-60 [nTPM]":"77.2","Cell RNA - HMC-1 [nTPM]":"67.5","Cell RNA - HSkMC [nTPM]":"55.5","Cell RNA - hTCEpi [nTPM]":"60.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"44.2","Cell RNA - hTERT-HME1 [nTPM]":"66.9","Cell RNA - hTERT-RPE1 [nTPM]":"38.0","Cell RNA - HUVEC TERT2 [nTPM]":"52.4","Cell RNA - JURKAT [nTPM]":"69.0","Cell RNA - K-562 [nTPM]":"58.0","Cell RNA - Karpas-707 [nTPM]":"34.5","Cell RNA - LHCN-M2 [nTPM]":"70.2","Cell RNA - MCF7 [nTPM]":"58.0","Cell RNA - MOLT-4 [nTPM]":"54.5","Cell RNA - NB-4 [nTPM]":"57.6","Cell RNA - NTERA-2 [nTPM]":"39.6","Cell RNA - OE19 [nTPM]":"132.2","Cell RNA - PC-3 [nTPM]":"39.7","Cell RNA - REH [nTPM]":"48.9","Cell RNA - RH-30 [nTPM]":"50.3","Cell RNA - RPMI-8226 [nTPM]":"43.1","Cell RNA - RPTEC TERT1 [nTPM]":"80.9","Cell RNA - RT4 [nTPM]":"74.4","Cell RNA - SCLC-21H [nTPM]":"45.8","Cell RNA - SH-SY5Y [nTPM]":"22.4","Cell RNA - SiHa [nTPM]":"43.5","Cell RNA - SK-BR-3 [nTPM]":"84.9","Cell RNA - SK-MEL-30 [nTPM]":"58.2","Cell RNA - SuSa [nTPM]":"42.0","Cell RNA - T-47d [nTPM]":"39.6","Cell RNA - THP-1 [nTPM]":"63.4","Cell RNA - TIME [nTPM]":"33.4","Cell RNA - U-138 MG [nTPM]":"43.5","Cell RNA - U-2 OS [nTPM]":"66.4","Cell RNA - U-2197 [nTPM]":"30.2","Cell RNA - U-251 MG [nTPM]":"50.4","Cell RNA - U-266\/70 [nTPM]":"16.4","Cell RNA - U-266\/84 [nTPM]":"33.3","Cell RNA - U-698 [nTPM]":"52.5","Cell RNA - U-87 MG [nTPM]":"38.4","Cell RNA - U-937 [nTPM]":"66.4","Cell RNA - WM-115 [nTPM]":"31.7","Blood RNA - basophil [nTPM]":"51.4","Blood RNA - classical monocyte [nTPM]":"90.7","Blood RNA - eosinophil [nTPM]":"43.8","Blood RNA - gdT-cell [nTPM]":"50.0","Blood RNA - intermediate monocyte [nTPM]":"90.9","Blood RNA - MAIT T-cell [nTPM]":"50.3","Blood RNA - memory B-cell [nTPM]":"54.8","Blood RNA - memory CD4 T-cell [nTPM]":"53.2","Blood RNA - memory CD8 T-cell [nTPM]":"51.9","Blood RNA - myeloid DC [nTPM]":"106.6","Blood RNA - naive B-cell [nTPM]":"48.0","Blood RNA - naive CD4 T-cell [nTPM]":"56.1","Blood RNA - naive CD8 T-cell [nTPM]":"53.6","Blood RNA - neutrophil [nTPM]":"27.3","Blood RNA - NK-cell [nTPM]":"49.2","Blood RNA - non-classical monocyte [nTPM]":"78.3","Blood RNA - plasmacytoid DC [nTPM]":"59.3","Blood RNA - T-reg [nTPM]":"68.4","Blood RNA - total PBMC [nTPM]":"166.2","Brain RNA - amygdala [nTPM]":"25.6","Brain RNA - basal ganglia [nTPM]":"26.7","Brain RNA - cerebellum [nTPM]":"29.4","Brain RNA - cerebral cortex [nTPM]":"31.1","Brain RNA - hippocampal formation [nTPM]":"27.2","Brain RNA - hypothalamus [nTPM]":"28.4","Brain RNA - medulla oblongata [nTPM]":"27.0","Brain RNA - midbrain [nTPM]":"27.4","Brain RNA - pons [nTPM]":"26.1","Brain RNA - spinal cord [nTPM]":"26.4","Brain RNA - thalamus [nTPM]":"29.3","Brain RNA - white matter [nTPM]":"26.0","Single Cell Type RNA - Adipocytes [nTPM]":"69.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"54.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"46.6","Single Cell Type RNA - Astrocytes [nTPM]":"16.6","Single Cell Type RNA - B-cells [nTPM]":"104.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"147.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"279.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"466.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"105.9","Single Cell Type RNA - Bipolar cells [nTPM]":"71.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"119.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"128.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1474.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"161.5","Single Cell Type RNA - Club cells [nTPM]":"201.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"114.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"282.0","Single Cell Type RNA - dendritic cells [nTPM]":"116.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"321.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1035.0","Single Cell Type RNA - Ductal cells [nTPM]":"245.2","Single Cell Type RNA - Early spermatids [nTPM]":"258.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"106.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"66.8","Single Cell Type RNA - Endothelial cells [nTPM]":"106.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"160.0","Single Cell Type RNA - Erythroid cells [nTPM]":"147.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"235.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"271.7","Single Cell Type RNA - Fibroblasts [nTPM]":"126.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"139.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"88.5","Single Cell Type RNA - granulocytes [nTPM]":"90.7","Single Cell Type RNA - Granulosa cells [nTPM]":"114.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"83.9","Single Cell Type RNA - Hepatocytes [nTPM]":"272.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"266.1","Single Cell Type RNA - Horizontal cells [nTPM]":"52.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"19.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"293.6","Single Cell Type RNA - Ionocytes [nTPM]":"317.3","Single Cell Type RNA - Kupffer cells [nTPM]":"160.6","Single Cell Type RNA - Langerhans cells [nTPM]":"109.6","Single Cell Type RNA - Late spermatids [nTPM]":"146.0","Single Cell Type RNA - Leydig cells [nTPM]":"92.2","Single Cell Type RNA - Macrophages [nTPM]":"136.6","Single Cell Type RNA - Melanocytes [nTPM]":"165.4","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"206.6","Single Cell Type RNA - Muller glia cells [nTPM]":"124.6","Single Cell Type RNA - NK-cells [nTPM]":"132.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"205.0","Single Cell Type RNA - Paneth cells [nTPM]":"225.8","Single Cell Type RNA - Peritubular cells [nTPM]":"81.6","Single Cell Type RNA - Plasma cells [nTPM]":"159.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"257.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"338.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"758.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"132.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"84.1","Single Cell Type RNA - Sertoli cells [nTPM]":"98.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"107.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"131.0","Single Cell Type RNA - Spermatocytes [nTPM]":"348.8","Single Cell Type RNA - Spermatogonia [nTPM]":"80.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"203.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"160.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"381.9","Single Cell Type RNA - T-cells [nTPM]":"109.5","Single Cell Type RNA - Theca cells [nTPM]":"209.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"407.4","Single Cell Type RNA - Urothelial cells [nTPM]":"372.1"},{"Gene":"UROC1","Gene synonym":["FLJ31300","HMFN0320"],"Ensembl":"ENSG00000159650","Gene description":"Urocanate hydratase 1","Uniprot":["Q96N76"],"Chromosome":"3","Position":"126481166-126517773","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Histidine metabolism"],"Molecular function":["Lyase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"336","RNA tissue specific nTPM":{"liver":"116.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hepatocytes":"62.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"100","RNA cancer specific FPKM":{"liver cancer":"12.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"NB-4":"4.0"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069863"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"670000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA069863":"AB_2732143"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.71e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.97e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"116.6","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"4.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"13.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"62.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"UROD","Gene synonym":[],"Ensembl":"ENSG00000126088","Gene description":"Uroporphyrinogen decarboxylase","Uniprot":["P06132"],"Chromosome":"1","Position":"45010950-45015575","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Heme biosynthesis","Porphyrin biosynthesis"],"Molecular function":["Decarboxylase","Lyase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Erythroid cells":"806.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"K-562":"420.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027468","HPA028668","HPA030350"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2600000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA027468":"AB_1858654","HPA028668":"AB_10603458","HPA030350":"AB_2673440"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.48e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.72e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-2"},"Tissue RNA - adipose tissue [nTPM]":"51.7","Tissue RNA - adrenal gland [nTPM]":"120.1","Tissue RNA - amygdala [nTPM]":"72.0","Tissue RNA - appendix [nTPM]":"25.5","Tissue RNA - basal ganglia [nTPM]":"73.9","Tissue RNA - bone marrow [nTPM]":"199.0","Tissue RNA - breast [nTPM]":"48.2","Tissue RNA - cerebellum [nTPM]":"72.0","Tissue RNA - cerebral cortex [nTPM]":"79.3","Tissue RNA - cervix [nTPM]":"40.8","Tissue RNA - choroid plexus [nTPM]":"77.2","Tissue RNA - colon [nTPM]":"49.3","Tissue RNA - duodenum [nTPM]":"29.2","Tissue RNA - endometrium 1 [nTPM]":"46.9","Tissue RNA - epididymis [nTPM]":"54.7","Tissue RNA - esophagus [nTPM]":"34.2","Tissue RNA - fallopian tube [nTPM]":"49.2","Tissue RNA - gallbladder [nTPM]":"30.8","Tissue RNA - heart muscle [nTPM]":"70.6","Tissue RNA - hippocampal formation [nTPM]":"73.1","Tissue RNA - hypothalamus [nTPM]":"74.5","Tissue RNA - kidney [nTPM]":"58.0","Tissue RNA - liver [nTPM]":"100.9","Tissue RNA - lung [nTPM]":"34.8","Tissue RNA - lymph node [nTPM]":"35.2","Tissue RNA - medulla oblongata [nTPM]":"72.1","Tissue RNA - midbrain [nTPM]":"73.4","Tissue RNA - ovary [nTPM]":"51.1","Tissue RNA - pancreas [nTPM]":"45.1","Tissue RNA - parathyroid gland [nTPM]":"115.0","Tissue RNA - pituitary gland [nTPM]":"42.6","Tissue RNA - placenta [nTPM]":"39.4","Tissue RNA - pons [nTPM]":"73.6","Tissue RNA - prostate [nTPM]":"35.1","Tissue RNA - rectum [nTPM]":"30.1","Tissue RNA - retina [nTPM]":"24.7","Tissue RNA - salivary gland [nTPM]":"61.4","Tissue RNA - seminal vesicle [nTPM]":"44.2","Tissue RNA - skeletal muscle [nTPM]":"75.9","Tissue RNA - skin 1 [nTPM]":"31.7","Tissue RNA - small intestine [nTPM]":"30.7","Tissue RNA - smooth muscle [nTPM]":"54.7","Tissue RNA - spinal cord [nTPM]":"72.9","Tissue RNA - spleen [nTPM]":"37.8","Tissue RNA - stomach 1 [nTPM]":"38.5","Tissue RNA - testis [nTPM]":"44.8","Tissue RNA - thalamus [nTPM]":"73.6","Tissue RNA - thymus [nTPM]":"44.0","Tissue RNA - thyroid gland [nTPM]":"54.0","Tissue RNA - tongue [nTPM]":"83.8","Tissue RNA - tonsil [nTPM]":"36.1","Tissue RNA - urinary bladder [nTPM]":"40.3","Tissue RNA - vagina [nTPM]":"32.7","Tissue RNA - white matter [nTPM]":"73.8","Cell RNA - A-431 [nTPM]":"66.0","Cell RNA - A549 [nTPM]":"42.5","Cell RNA - AF22 [nTPM]":"67.0","Cell RNA - AN3-CA [nTPM]":"89.1","Cell RNA - ASC diff [nTPM]":"113.4","Cell RNA - ASC TERT1 [nTPM]":"107.7","Cell RNA - BEWO [nTPM]":"31.8","Cell RNA - BJ [nTPM]":"87.4","Cell RNA - BJ hTERT+ [nTPM]":"209.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"163.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"125.2","Cell RNA - CACO-2 [nTPM]":"59.9","Cell RNA - CAPAN-2 [nTPM]":"32.3","Cell RNA - Daudi [nTPM]":"46.4","Cell RNA - EFO-21 [nTPM]":"82.3","Cell RNA - fHDF\/TERT166 [nTPM]":"122.8","Cell RNA - GAMG [nTPM]":"116.3","Cell RNA - HaCaT [nTPM]":"31.1","Cell RNA - HAP1 [nTPM]":"127.2","Cell RNA - HBEC3-KT [nTPM]":"153.6","Cell RNA - HBF TERT88 [nTPM]":"116.9","Cell RNA - HDLM-2 [nTPM]":"42.9","Cell RNA - HEK 293 [nTPM]":"133.4","Cell RNA - HEL [nTPM]":"245.4","Cell RNA - HeLa [nTPM]":"95.4","Cell RNA - Hep G2 [nTPM]":"200.7","Cell RNA - HHSteC [nTPM]":"132.4","Cell RNA - HL-60 [nTPM]":"79.0","Cell RNA - HMC-1 [nTPM]":"42.6","Cell RNA - HSkMC [nTPM]":"115.1","Cell RNA - hTCEpi [nTPM]":"97.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"154.1","Cell RNA - hTERT-HME1 [nTPM]":"132.3","Cell RNA - hTERT-RPE1 [nTPM]":"121.8","Cell RNA - HUVEC TERT2 [nTPM]":"208.9","Cell RNA - JURKAT [nTPM]":"92.9","Cell RNA - K-562 [nTPM]":"420.8","Cell RNA - Karpas-707 [nTPM]":"48.5","Cell RNA - LHCN-M2 [nTPM]":"157.6","Cell RNA - MCF7 [nTPM]":"53.5","Cell RNA - MOLT-4 [nTPM]":"49.9","Cell RNA - NB-4 [nTPM]":"62.9","Cell RNA - NTERA-2 [nTPM]":"104.1","Cell RNA - OE19 [nTPM]":"51.5","Cell RNA - PC-3 [nTPM]":"145.9","Cell RNA - REH [nTPM]":"76.5","Cell RNA - RH-30 [nTPM]":"96.5","Cell RNA - RPMI-8226 [nTPM]":"69.9","Cell RNA - RPTEC TERT1 [nTPM]":"141.7","Cell RNA - RT4 [nTPM]":"54.4","Cell RNA - SCLC-21H [nTPM]":"73.9","Cell RNA - SH-SY5Y [nTPM]":"57.3","Cell RNA - SiHa [nTPM]":"89.1","Cell RNA - SK-BR-3 [nTPM]":"63.9","Cell RNA - SK-MEL-30 [nTPM]":"134.3","Cell RNA - SuSa [nTPM]":"73.7","Cell RNA - T-47d [nTPM]":"50.8","Cell RNA - THP-1 [nTPM]":"77.6","Cell RNA - TIME [nTPM]":"137.5","Cell RNA - U-138 MG [nTPM]":"96.9","Cell RNA - U-2 OS [nTPM]":"71.6","Cell RNA - U-2197 [nTPM]":"34.2","Cell RNA - U-251 MG [nTPM]":"130.5","Cell RNA - U-266\/70 [nTPM]":"49.4","Cell RNA - U-266\/84 [nTPM]":"60.1","Cell RNA - U-698 [nTPM]":"38.1","Cell RNA - U-87 MG [nTPM]":"141.0","Cell RNA - U-937 [nTPM]":"117.6","Cell RNA - WM-115 [nTPM]":"47.2","Blood RNA - basophil [nTPM]":"72.3","Blood RNA - classical monocyte [nTPM]":"111.9","Blood RNA - eosinophil [nTPM]":"65.5","Blood RNA - gdT-cell [nTPM]":"57.4","Blood RNA - intermediate monocyte [nTPM]":"81.5","Blood RNA - MAIT T-cell [nTPM]":"58.8","Blood RNA - memory B-cell [nTPM]":"84.9","Blood RNA - memory CD4 T-cell [nTPM]":"69.2","Blood RNA - memory CD8 T-cell [nTPM]":"56.7","Blood RNA - myeloid DC [nTPM]":"149.7","Blood RNA - naive B-cell [nTPM]":"81.9","Blood RNA - naive CD4 T-cell [nTPM]":"63.6","Blood RNA - naive CD8 T-cell [nTPM]":"58.0","Blood RNA - neutrophil [nTPM]":"20.1","Blood RNA - NK-cell [nTPM]":"87.4","Blood RNA - non-classical monocyte [nTPM]":"50.9","Blood RNA - plasmacytoid DC [nTPM]":"102.3","Blood RNA - T-reg [nTPM]":"88.7","Blood RNA - total PBMC [nTPM]":"122.1","Brain RNA - amygdala [nTPM]":"72.0","Brain RNA - basal ganglia [nTPM]":"73.9","Brain RNA - cerebellum [nTPM]":"72.0","Brain RNA - cerebral cortex [nTPM]":"79.3","Brain RNA - hippocampal formation [nTPM]":"73.1","Brain RNA - hypothalamus [nTPM]":"74.5","Brain RNA - medulla oblongata [nTPM]":"72.1","Brain RNA - midbrain [nTPM]":"73.4","Brain RNA - pons [nTPM]":"73.6","Brain RNA - spinal cord [nTPM]":"72.9","Brain RNA - thalamus [nTPM]":"73.6","Brain RNA - white matter [nTPM]":"73.8","Single Cell Type RNA - Adipocytes [nTPM]":"25.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"38.0","Single Cell Type RNA - Astrocytes [nTPM]":"7.8","Single Cell Type RNA - B-cells [nTPM]":"25.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"22.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"35.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"101.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"43.9","Single Cell Type RNA - Bipolar cells [nTPM]":"27.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"31.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"37.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"74.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"41.5","Single Cell Type RNA - Club cells [nTPM]":"45.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"98.6","Single Cell Type RNA - dendritic cells [nTPM]":"22.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"21.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"90.1","Single Cell Type RNA - Ductal cells [nTPM]":"73.5","Single Cell Type RNA - Early spermatids [nTPM]":"8.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"30.7","Single Cell Type RNA - Endothelial cells [nTPM]":"42.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.0","Single Cell Type RNA - Erythroid cells [nTPM]":"806.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"63.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"54.6","Single Cell Type RNA - Fibroblasts [nTPM]":"57.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.2","Single Cell Type RNA - granulocytes [nTPM]":"52.6","Single Cell Type RNA - Granulosa cells [nTPM]":"20.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"38.6","Single Cell Type RNA - Hepatocytes [nTPM]":"98.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"101.8","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.2","Single Cell Type RNA - Ionocytes [nTPM]":"73.2","Single Cell Type RNA - Kupffer cells [nTPM]":"37.9","Single Cell Type RNA - Langerhans cells [nTPM]":"29.4","Single Cell Type RNA - Late spermatids [nTPM]":"16.2","Single Cell Type RNA - Leydig cells [nTPM]":"79.6","Single Cell Type RNA - Macrophages [nTPM]":"38.5","Single Cell Type RNA - Melanocytes [nTPM]":"48.0","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"103.6","Single Cell Type RNA - Muller glia cells [nTPM]":"89.7","Single Cell Type RNA - NK-cells [nTPM]":"24.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"51.2","Single Cell Type RNA - Paneth cells [nTPM]":"23.7","Single Cell Type RNA - Peritubular cells [nTPM]":"56.1","Single Cell Type RNA - Plasma cells [nTPM]":"36.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"32.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"134.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"32.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"25.3","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"29.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"75.0","Single Cell Type RNA - Spermatocytes [nTPM]":"37.3","Single Cell Type RNA - Spermatogonia [nTPM]":"42.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"31.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"49.8","Single Cell Type RNA - T-cells [nTPM]":"23.3","Single Cell Type RNA - Theca cells [nTPM]":"72.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.9","Single Cell Type RNA - Urothelial cells [nTPM]":"29.1"},{"Gene":"UROS","Gene synonym":[],"Ensembl":"ENSG00000188690","Gene description":"Uroporphyrinogen III synthase","Uniprot":["P10746"],"Chromosome":"10","Position":"125784980-125823258","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Heme biosynthesis","Porphyrin biosynthesis"],"Molecular function":["Lyase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"231.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044038"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"69000","Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA044038":"AB_10966692"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.27e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-1"},"Tissue RNA - adipose tissue [nTPM]":"27.9","Tissue RNA - adrenal gland [nTPM]":"41.3","Tissue RNA - amygdala [nTPM]":"54.1","Tissue RNA - appendix [nTPM]":"13.4","Tissue RNA - basal ganglia [nTPM]":"55.3","Tissue RNA - bone marrow [nTPM]":"67.5","Tissue RNA - breast [nTPM]":"26.9","Tissue RNA - cerebellum [nTPM]":"40.6","Tissue RNA - cerebral cortex [nTPM]":"64.5","Tissue RNA - cervix [nTPM]":"15.9","Tissue RNA - choroid plexus [nTPM]":"33.0","Tissue RNA - colon [nTPM]":"29.9","Tissue RNA - duodenum [nTPM]":"20.9","Tissue RNA - endometrium 1 [nTPM]":"21.4","Tissue RNA - epididymis [nTPM]":"56.9","Tissue RNA - esophagus [nTPM]":"24.9","Tissue RNA - fallopian tube [nTPM]":"19.3","Tissue RNA - gallbladder [nTPM]":"15.6","Tissue RNA - heart muscle [nTPM]":"73.2","Tissue RNA - hippocampal formation [nTPM]":"56.3","Tissue RNA - hypothalamus [nTPM]":"45.8","Tissue RNA - kidney [nTPM]":"40.7","Tissue RNA - liver [nTPM]":"59.7","Tissue RNA - lung [nTPM]":"20.5","Tissue RNA - lymph node [nTPM]":"18.8","Tissue RNA - medulla oblongata [nTPM]":"41.6","Tissue RNA - midbrain [nTPM]":"48.1","Tissue RNA - ovary [nTPM]":"22.5","Tissue RNA - pancreas [nTPM]":"32.9","Tissue RNA - parathyroid gland [nTPM]":"30.0","Tissue RNA - pituitary gland [nTPM]":"29.9","Tissue RNA - placenta [nTPM]":"11.3","Tissue RNA - pons [nTPM]":"43.5","Tissue RNA - prostate [nTPM]":"27.4","Tissue RNA - rectum [nTPM]":"16.5","Tissue RNA - retina [nTPM]":"26.2","Tissue RNA - salivary gland [nTPM]":"29.6","Tissue RNA - seminal vesicle [nTPM]":"19.1","Tissue RNA - skeletal muscle [nTPM]":"83.8","Tissue RNA - skin 1 [nTPM]":"23.0","Tissue RNA - small intestine [nTPM]":"24.2","Tissue RNA - smooth muscle [nTPM]":"18.1","Tissue RNA - spinal cord [nTPM]":"40.2","Tissue RNA - spleen [nTPM]":"28.0","Tissue RNA - stomach 1 [nTPM]":"29.6","Tissue RNA - testis [nTPM]":"31.2","Tissue RNA - thalamus [nTPM]":"51.8","Tissue RNA - thymus [nTPM]":"18.6","Tissue RNA - thyroid gland [nTPM]":"32.5","Tissue RNA - tongue [nTPM]":"80.0","Tissue RNA - tonsil [nTPM]":"19.1","Tissue RNA - urinary bladder [nTPM]":"27.3","Tissue RNA - vagina [nTPM]":"17.0","Tissue RNA - white matter [nTPM]":"47.8","Cell RNA - A-431 [nTPM]":"45.5","Cell RNA - A549 [nTPM]":"56.3","Cell RNA - AF22 [nTPM]":"29.8","Cell RNA - AN3-CA [nTPM]":"74.9","Cell RNA - ASC diff [nTPM]":"38.5","Cell RNA - ASC TERT1 [nTPM]":"42.2","Cell RNA - BEWO [nTPM]":"51.9","Cell RNA - BJ [nTPM]":"51.4","Cell RNA - BJ hTERT+ [nTPM]":"94.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"39.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"34.6","Cell RNA - CACO-2 [nTPM]":"22.9","Cell RNA - CAPAN-2 [nTPM]":"54.0","Cell RNA - Daudi [nTPM]":"58.4","Cell RNA - EFO-21 [nTPM]":"24.7","Cell RNA - fHDF\/TERT166 [nTPM]":"72.9","Cell RNA - GAMG [nTPM]":"24.3","Cell RNA - HaCaT [nTPM]":"23.5","Cell RNA - HAP1 [nTPM]":"18.5","Cell RNA - HBEC3-KT [nTPM]":"43.1","Cell RNA - HBF TERT88 [nTPM]":"31.3","Cell RNA - HDLM-2 [nTPM]":"78.1","Cell RNA - HEK 293 [nTPM]":"39.9","Cell RNA - HEL [nTPM]":"125.3","Cell RNA - HeLa [nTPM]":"27.9","Cell RNA - Hep G2 [nTPM]":"40.1","Cell RNA - HHSteC [nTPM]":"67.3","Cell RNA - HL-60 [nTPM]":"50.7","Cell RNA - HMC-1 [nTPM]":"29.7","Cell RNA - HSkMC [nTPM]":"59.3","Cell RNA - hTCEpi [nTPM]":"20.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.8","Cell RNA - hTERT-HME1 [nTPM]":"66.0","Cell RNA - hTERT-RPE1 [nTPM]":"47.5","Cell RNA - HUVEC TERT2 [nTPM]":"34.4","Cell RNA - JURKAT [nTPM]":"48.5","Cell RNA - K-562 [nTPM]":"24.4","Cell RNA - Karpas-707 [nTPM]":"54.1","Cell RNA - LHCN-M2 [nTPM]":"63.5","Cell RNA - MCF7 [nTPM]":"65.2","Cell RNA - MOLT-4 [nTPM]":"51.2","Cell RNA - NB-4 [nTPM]":"72.8","Cell RNA - NTERA-2 [nTPM]":"37.7","Cell RNA - OE19 [nTPM]":"31.8","Cell RNA - PC-3 [nTPM]":"54.0","Cell RNA - REH [nTPM]":"33.1","Cell RNA - RH-30 [nTPM]":"34.1","Cell RNA - RPMI-8226 [nTPM]":"37.3","Cell RNA - RPTEC TERT1 [nTPM]":"53.9","Cell RNA - RT4 [nTPM]":"28.2","Cell RNA - SCLC-21H [nTPM]":"26.2","Cell RNA - SH-SY5Y [nTPM]":"46.8","Cell RNA - SiHa [nTPM]":"51.6","Cell RNA - SK-BR-3 [nTPM]":"41.8","Cell RNA - SK-MEL-30 [nTPM]":"80.7","Cell RNA - SuSa [nTPM]":"30.8","Cell RNA - T-47d [nTPM]":"40.4","Cell RNA - THP-1 [nTPM]":"59.1","Cell RNA - TIME [nTPM]":"33.8","Cell RNA - U-138 MG [nTPM]":"52.3","Cell RNA - U-2 OS [nTPM]":"19.6","Cell RNA - U-2197 [nTPM]":"38.1","Cell RNA - U-251 MG [nTPM]":"48.2","Cell RNA - U-266\/70 [nTPM]":"50.7","Cell RNA - U-266\/84 [nTPM]":"36.8","Cell RNA - U-698 [nTPM]":"40.6","Cell RNA - U-87 MG [nTPM]":"75.6","Cell RNA - U-937 [nTPM]":"23.1","Cell RNA - WM-115 [nTPM]":"26.3","Blood RNA - basophil [nTPM]":"4.9","Blood RNA - classical monocyte [nTPM]":"31.9","Blood RNA - eosinophil [nTPM]":"4.6","Blood RNA - gdT-cell [nTPM]":"30.1","Blood RNA - intermediate monocyte [nTPM]":"33.1","Blood RNA - MAIT T-cell [nTPM]":"33.9","Blood RNA - memory B-cell [nTPM]":"30.1","Blood RNA - memory CD4 T-cell [nTPM]":"29.3","Blood RNA - memory CD8 T-cell [nTPM]":"38.6","Blood RNA - myeloid DC [nTPM]":"53.5","Blood RNA - naive B-cell [nTPM]":"37.5","Blood RNA - naive CD4 T-cell [nTPM]":"38.1","Blood RNA - naive CD8 T-cell [nTPM]":"29.6","Blood RNA - neutrophil [nTPM]":"2.1","Blood RNA - NK-cell [nTPM]":"53.6","Blood RNA - non-classical monocyte [nTPM]":"31.9","Blood RNA - plasmacytoid DC [nTPM]":"25.3","Blood RNA - T-reg [nTPM]":"29.8","Blood RNA - total PBMC [nTPM]":"38.1","Brain RNA - amygdala [nTPM]":"54.1","Brain RNA - basal ganglia [nTPM]":"55.3","Brain RNA - cerebellum [nTPM]":"40.6","Brain RNA - cerebral cortex [nTPM]":"64.5","Brain RNA - hippocampal formation [nTPM]":"56.3","Brain RNA - hypothalamus [nTPM]":"45.8","Brain RNA - medulla oblongata [nTPM]":"41.6","Brain RNA - midbrain [nTPM]":"48.1","Brain RNA - pons [nTPM]":"43.5","Brain RNA - spinal cord [nTPM]":"40.2","Brain RNA - thalamus [nTPM]":"51.8","Brain RNA - white matter [nTPM]":"47.8","Single Cell Type RNA - Adipocytes [nTPM]":"19.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.1","Single Cell Type RNA - Astrocytes [nTPM]":"20.5","Single Cell Type RNA - B-cells [nTPM]":"34.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"31.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"49.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"36.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"39.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"70.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"40.0","Single Cell Type RNA - Club cells [nTPM]":"28.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"60.8","Single Cell Type RNA - dendritic cells [nTPM]":"36.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"19.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"101.8","Single Cell Type RNA - Ductal cells [nTPM]":"59.7","Single Cell Type RNA - Early spermatids [nTPM]":"57.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"25.5","Single Cell Type RNA - Endothelial cells [nTPM]":"22.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.5","Single Cell Type RNA - Erythroid cells [nTPM]":"231.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"59.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"47.4","Single Cell Type RNA - Fibroblasts [nTPM]":"33.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.9","Single Cell Type RNA - granulocytes [nTPM]":"11.4","Single Cell Type RNA - Granulosa cells [nTPM]":"112.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.2","Single Cell Type RNA - Hepatocytes [nTPM]":"53.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"79.3","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"25.6","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"47.8","Single Cell Type RNA - Langerhans cells [nTPM]":"20.8","Single Cell Type RNA - Late spermatids [nTPM]":"123.7","Single Cell Type RNA - Leydig cells [nTPM]":"35.8","Single Cell Type RNA - Macrophages [nTPM]":"31.6","Single Cell Type RNA - Melanocytes [nTPM]":"62.2","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"58.7","Single Cell Type RNA - Muller glia cells [nTPM]":"77.0","Single Cell Type RNA - NK-cells [nTPM]":"69.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"29.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"42.7","Single Cell Type RNA - Paneth cells [nTPM]":"15.8","Single Cell Type RNA - Peritubular cells [nTPM]":"40.6","Single Cell Type RNA - Plasma cells [nTPM]":"46.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"27.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"52.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"142.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"42.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"36.7","Single Cell Type RNA - Spermatocytes [nTPM]":"55.7","Single Cell Type RNA - Spermatogonia [nTPM]":"100.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.0","Single Cell Type RNA - T-cells [nTPM]":"37.8","Single Cell Type RNA - Theca cells [nTPM]":"55.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"38.8","Single Cell Type RNA - Urothelial cells [nTPM]":"21.3"},{"Gene":"USP16","Gene synonym":["Ubp-M"],"Ensembl":"ENSG00000156256","Gene description":"Ubiquitin specific peptidase 16","Uniprot":["Q9Y5T5"],"Chromosome":"21","Position":"29024629-29054488","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Mitosis","Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["Activator","Chromatin regulator","Hydrolase","Protease","Thiol protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"514.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021140"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA021140":"AB_1858668"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Tissue RNA - adipose tissue [nTPM]":"27.0","Tissue RNA - adrenal gland [nTPM]":"23.0","Tissue RNA - amygdala [nTPM]":"18.8","Tissue RNA - appendix [nTPM]":"23.4","Tissue RNA - basal ganglia [nTPM]":"23.2","Tissue RNA - bone marrow [nTPM]":"29.3","Tissue RNA - breast [nTPM]":"27.4","Tissue RNA - cerebellum [nTPM]":"21.3","Tissue RNA - cerebral cortex [nTPM]":"20.4","Tissue RNA - cervix [nTPM]":"22.7","Tissue RNA - choroid plexus [nTPM]":"19.1","Tissue RNA - colon [nTPM]":"24.6","Tissue RNA - duodenum [nTPM]":"25.1","Tissue RNA - endometrium 1 [nTPM]":"25.2","Tissue RNA - epididymis [nTPM]":"25.2","Tissue RNA - esophagus [nTPM]":"25.2","Tissue RNA - fallopian tube [nTPM]":"19.9","Tissue RNA - gallbladder [nTPM]":"20.4","Tissue RNA - heart muscle [nTPM]":"29.3","Tissue RNA - hippocampal formation [nTPM]":"17.5","Tissue RNA - hypothalamus [nTPM]":"20.5","Tissue RNA - kidney [nTPM]":"22.1","Tissue RNA - liver [nTPM]":"30.7","Tissue RNA - lung [nTPM]":"20.9","Tissue RNA - lymph node [nTPM]":"27.9","Tissue RNA - medulla oblongata [nTPM]":"20.5","Tissue RNA - midbrain [nTPM]":"20.8","Tissue RNA - ovary [nTPM]":"22.3","Tissue RNA - pancreas [nTPM]":"26.0","Tissue RNA - parathyroid gland [nTPM]":"34.3","Tissue RNA - pituitary gland [nTPM]":"16.7","Tissue RNA - placenta [nTPM]":"24.2","Tissue RNA - pons [nTPM]":"21.7","Tissue RNA - prostate [nTPM]":"25.7","Tissue RNA - rectum [nTPM]":"26.4","Tissue RNA - retina [nTPM]":"42.3","Tissue RNA - salivary gland [nTPM]":"24.7","Tissue RNA - seminal vesicle [nTPM]":"23.6","Tissue RNA - skeletal muscle [nTPM]":"34.7","Tissue RNA - skin 1 [nTPM]":"19.9","Tissue RNA - small intestine [nTPM]":"22.8","Tissue RNA - smooth muscle [nTPM]":"22.6","Tissue RNA - spinal cord [nTPM]":"20.2","Tissue RNA - spleen [nTPM]":"21.9","Tissue RNA - stomach 1 [nTPM]":"23.4","Tissue RNA - testis [nTPM]":"25.7","Tissue RNA - thalamus [nTPM]":"20.3","Tissue RNA - thymus [nTPM]":"30.0","Tissue RNA - thyroid gland [nTPM]":"33.8","Tissue RNA - tongue [nTPM]":"37.5","Tissue RNA - tonsil [nTPM]":"32.3","Tissue RNA - urinary bladder [nTPM]":"27.1","Tissue RNA - vagina [nTPM]":"14.1","Tissue RNA - white matter [nTPM]":"27.5","Cell RNA - A-431 [nTPM]":"59.9","Cell RNA - A549 [nTPM]":"23.4","Cell RNA - AF22 [nTPM]":"36.5","Cell RNA - AN3-CA [nTPM]":"33.0","Cell RNA - ASC diff [nTPM]":"25.4","Cell RNA - ASC TERT1 [nTPM]":"41.5","Cell RNA - BEWO [nTPM]":"34.2","Cell RNA - BJ [nTPM]":"56.9","Cell RNA - BJ hTERT+ [nTPM]":"37.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"38.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"36.4","Cell RNA - CACO-2 [nTPM]":"29.5","Cell RNA - CAPAN-2 [nTPM]":"38.3","Cell RNA - Daudi [nTPM]":"60.5","Cell RNA - EFO-21 [nTPM]":"16.8","Cell RNA - fHDF\/TERT166 [nTPM]":"54.8","Cell RNA - GAMG [nTPM]":"58.7","Cell RNA - HaCaT [nTPM]":"26.5","Cell RNA - HAP1 [nTPM]":"45.6","Cell RNA - HBEC3-KT [nTPM]":"41.5","Cell RNA - HBF TERT88 [nTPM]":"50.1","Cell RNA - HDLM-2 [nTPM]":"58.6","Cell RNA - HEK 293 [nTPM]":"48.4","Cell RNA - HEL [nTPM]":"80.9","Cell RNA - HeLa [nTPM]":"27.3","Cell RNA - Hep G2 [nTPM]":"33.1","Cell RNA - HHSteC [nTPM]":"37.6","Cell RNA - HL-60 [nTPM]":"80.3","Cell RNA - HMC-1 [nTPM]":"43.0","Cell RNA - HSkMC [nTPM]":"35.9","Cell RNA - hTCEpi [nTPM]":"42.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"50.3","Cell RNA - hTERT-HME1 [nTPM]":"46.4","Cell RNA - hTERT-RPE1 [nTPM]":"28.7","Cell RNA - HUVEC TERT2 [nTPM]":"37.5","Cell RNA - JURKAT [nTPM]":"33.9","Cell RNA - K-562 [nTPM]":"67.7","Cell RNA - Karpas-707 [nTPM]":"103.8","Cell RNA - LHCN-M2 [nTPM]":"45.3","Cell RNA - MCF7 [nTPM]":"27.3","Cell RNA - MOLT-4 [nTPM]":"49.7","Cell RNA - NB-4 [nTPM]":"29.3","Cell RNA - NTERA-2 [nTPM]":"39.2","Cell RNA - OE19 [nTPM]":"48.4","Cell RNA - PC-3 [nTPM]":"29.9","Cell RNA - REH [nTPM]":"33.0","Cell RNA - RH-30 [nTPM]":"89.7","Cell RNA - RPMI-8226 [nTPM]":"69.6","Cell RNA - RPTEC TERT1 [nTPM]":"31.7","Cell RNA - RT4 [nTPM]":"42.5","Cell RNA - SCLC-21H [nTPM]":"39.4","Cell RNA - SH-SY5Y [nTPM]":"41.9","Cell RNA - SiHa [nTPM]":"36.8","Cell RNA - SK-BR-3 [nTPM]":"58.1","Cell RNA - SK-MEL-30 [nTPM]":"51.1","Cell RNA - SuSa [nTPM]":"24.9","Cell RNA - T-47d [nTPM]":"40.2","Cell RNA - THP-1 [nTPM]":"54.2","Cell RNA - TIME [nTPM]":"38.0","Cell RNA - U-138 MG [nTPM]":"44.8","Cell RNA - U-2 OS [nTPM]":"55.7","Cell RNA - U-2197 [nTPM]":"41.8","Cell RNA - U-251 MG [nTPM]":"59.3","Cell RNA - U-266\/70 [nTPM]":"87.8","Cell RNA - U-266\/84 [nTPM]":"129.3","Cell RNA - U-698 [nTPM]":"62.5","Cell RNA - U-87 MG [nTPM]":"46.8","Cell RNA - U-937 [nTPM]":"57.3","Cell RNA - WM-115 [nTPM]":"45.6","Blood RNA - basophil [nTPM]":"37.4","Blood RNA - classical monocyte [nTPM]":"24.1","Blood RNA - eosinophil [nTPM]":"33.6","Blood RNA - gdT-cell [nTPM]":"36.3","Blood RNA - intermediate monocyte [nTPM]":"24.9","Blood RNA - MAIT T-cell [nTPM]":"28.6","Blood RNA - memory B-cell [nTPM]":"40.7","Blood RNA - memory CD4 T-cell [nTPM]":"34.1","Blood RNA - memory CD8 T-cell [nTPM]":"33.6","Blood RNA - myeloid DC [nTPM]":"23.1","Blood RNA - naive B-cell [nTPM]":"46.0","Blood RNA - naive CD4 T-cell [nTPM]":"36.9","Blood RNA - naive CD8 T-cell [nTPM]":"35.8","Blood RNA - neutrophil [nTPM]":"23.5","Blood RNA - NK-cell [nTPM]":"31.5","Blood RNA - non-classical monocyte [nTPM]":"34.0","Blood RNA - plasmacytoid DC [nTPM]":"36.2","Blood RNA - T-reg [nTPM]":"38.9","Blood RNA - total PBMC [nTPM]":"17.2","Brain RNA - amygdala [nTPM]":"18.8","Brain RNA - basal ganglia [nTPM]":"23.2","Brain RNA - cerebellum [nTPM]":"21.3","Brain RNA - cerebral cortex [nTPM]":"20.4","Brain RNA - hippocampal formation [nTPM]":"17.5","Brain RNA - hypothalamus [nTPM]":"20.5","Brain RNA - medulla oblongata [nTPM]":"20.5","Brain RNA - midbrain [nTPM]":"20.8","Brain RNA - pons [nTPM]":"21.7","Brain RNA - spinal cord [nTPM]":"20.2","Brain RNA - thalamus [nTPM]":"20.3","Brain RNA - white matter [nTPM]":"27.5","Single Cell Type RNA - Adipocytes [nTPM]":"60.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"86.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"91.9","Single Cell Type RNA - Astrocytes [nTPM]":"27.4","Single Cell Type RNA - B-cells [nTPM]":"114.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"57.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"132.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"68.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"55.2","Single Cell Type RNA - Bipolar cells [nTPM]":"161.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"65.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"58.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"84.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"64.3","Single Cell Type RNA - Club cells [nTPM]":"83.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"53.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"89.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"81.7","Single Cell Type RNA - dendritic cells [nTPM]":"108.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"90.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"133.1","Single Cell Type RNA - Ductal cells [nTPM]":"77.9","Single Cell Type RNA - Early spermatids [nTPM]":"514.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"85.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"82.6","Single Cell Type RNA - Endothelial cells [nTPM]":"55.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"82.6","Single Cell Type RNA - Erythroid cells [nTPM]":"40.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"119.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"79.7","Single Cell Type RNA - Fibroblasts [nTPM]":"68.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"55.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"107.7","Single Cell Type RNA - granulocytes [nTPM]":"141.8","Single Cell Type RNA - Granulosa cells [nTPM]":"61.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"45.7","Single Cell Type RNA - Hepatocytes [nTPM]":"86.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"59.9","Single Cell Type RNA - Horizontal cells [nTPM]":"72.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"27.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"100.4","Single Cell Type RNA - Ionocytes [nTPM]":"44.7","Single Cell Type RNA - Kupffer cells [nTPM]":"62.0","Single Cell Type RNA - Langerhans cells [nTPM]":"53.1","Single Cell Type RNA - Late spermatids [nTPM]":"117.0","Single Cell Type RNA - Leydig cells [nTPM]":"87.7","Single Cell Type RNA - Macrophages [nTPM]":"69.4","Single Cell Type RNA - Melanocytes [nTPM]":"62.2","Single Cell Type RNA - Microglial cells [nTPM]":"25.3","Single Cell Type RNA - monocytes [nTPM]":"117.3","Single Cell Type RNA - Muller glia cells [nTPM]":"94.1","Single Cell Type RNA - NK-cells [nTPM]":"96.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"28.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"47.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"94.0","Single Cell Type RNA - Paneth cells [nTPM]":"99.2","Single Cell Type RNA - Peritubular cells [nTPM]":"86.9","Single Cell Type RNA - Plasma cells [nTPM]":"106.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"100.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"74.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"91.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"94.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"183.5","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"133.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"83.2","Single Cell Type RNA - Spermatocytes [nTPM]":"100.4","Single Cell Type RNA - Spermatogonia [nTPM]":"82.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"68.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"64.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"162.0","Single Cell Type RNA - T-cells [nTPM]":"105.3","Single Cell Type RNA - Theca cells [nTPM]":"72.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"90.6","Single Cell Type RNA - Urothelial cells [nTPM]":"141.9"},{"Gene":"USP18","Gene synonym":[],"Ensembl":"ENSG00000184979","Gene description":"Ubiquitin specific peptidase 18","Uniprot":["Q9UMW8"],"Chromosome":"22","Position":"18150170-18177397","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"46.9","Extravillous trophoblasts":"31.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+ SV40 Large T+":"181.8","BJ hTERT+ SV40 Large T+ RasG12V":"196.2"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044768"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA044768":"AB_10963697"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.8","Tissue RNA - adrenal gland [nTPM]":"5.0","Tissue RNA - amygdala [nTPM]":"3.6","Tissue RNA - appendix [nTPM]":"5.1","Tissue RNA - basal ganglia [nTPM]":"3.8","Tissue RNA - bone marrow [nTPM]":"8.1","Tissue RNA - breast [nTPM]":"8.3","Tissue RNA - cerebellum [nTPM]":"3.3","Tissue RNA - cerebral cortex [nTPM]":"4.5","Tissue RNA - cervix [nTPM]":"4.0","Tissue RNA - choroid plexus [nTPM]":"4.0","Tissue RNA - colon [nTPM]":"5.0","Tissue RNA - duodenum [nTPM]":"6.0","Tissue RNA - endometrium 1 [nTPM]":"3.2","Tissue RNA - epididymis [nTPM]":"7.8","Tissue RNA - esophagus [nTPM]":"4.0","Tissue RNA - fallopian tube [nTPM]":"7.3","Tissue RNA - gallbladder [nTPM]":"6.6","Tissue RNA - heart muscle [nTPM]":"4.4","Tissue RNA - hippocampal formation [nTPM]":"3.7","Tissue RNA - hypothalamus [nTPM]":"3.9","Tissue RNA - kidney [nTPM]":"5.9","Tissue RNA - liver [nTPM]":"23.6","Tissue RNA - lung [nTPM]":"7.9","Tissue RNA - lymph node [nTPM]":"9.2","Tissue RNA - medulla oblongata [nTPM]":"5.1","Tissue RNA - midbrain [nTPM]":"3.9","Tissue RNA - ovary [nTPM]":"2.9","Tissue RNA - pancreas [nTPM]":"4.2","Tissue RNA - parathyroid gland [nTPM]":"3.6","Tissue RNA - pituitary gland [nTPM]":"5.7","Tissue RNA - placenta [nTPM]":"5.7","Tissue RNA - pons [nTPM]":"4.2","Tissue RNA - prostate [nTPM]":"5.3","Tissue RNA - rectum [nTPM]":"4.4","Tissue RNA - retina [nTPM]":"0.7","Tissue RNA - salivary gland [nTPM]":"14.0","Tissue RNA - seminal vesicle [nTPM]":"2.5","Tissue RNA - skeletal muscle [nTPM]":"3.8","Tissue RNA - skin 1 [nTPM]":"3.4","Tissue RNA - small intestine [nTPM]":"6.7","Tissue RNA - smooth muscle [nTPM]":"4.0","Tissue RNA - spinal cord [nTPM]":"7.0","Tissue RNA - spleen [nTPM]":"11.0","Tissue RNA - stomach 1 [nTPM]":"7.2","Tissue RNA - testis [nTPM]":"9.7","Tissue RNA - thalamus [nTPM]":"4.1","Tissue RNA - thymus [nTPM]":"15.0","Tissue RNA - thyroid gland [nTPM]":"7.3","Tissue RNA - tongue [nTPM]":"5.5","Tissue RNA - tonsil [nTPM]":"6.5","Tissue RNA - urinary bladder [nTPM]":"4.0","Tissue RNA - vagina [nTPM]":"3.6","Tissue RNA - white matter [nTPM]":"3.7","Cell RNA - A-431 [nTPM]":"14.4","Cell RNA - A549 [nTPM]":"14.6","Cell RNA - AF22 [nTPM]":"4.2","Cell RNA - AN3-CA [nTPM]":"18.2","Cell RNA - ASC diff [nTPM]":"18.2","Cell RNA - ASC TERT1 [nTPM]":"13.5","Cell RNA - BEWO [nTPM]":"18.4","Cell RNA - BJ [nTPM]":"7.3","Cell RNA - BJ hTERT+ [nTPM]":"17.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"181.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"196.2","Cell RNA - CACO-2 [nTPM]":"2.2","Cell RNA - CAPAN-2 [nTPM]":"20.1","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"10.8","Cell RNA - fHDF\/TERT166 [nTPM]":"4.0","Cell RNA - GAMG [nTPM]":"57.5","Cell RNA - HaCaT [nTPM]":"4.9","Cell RNA - HAP1 [nTPM]":"21.6","Cell RNA - HBEC3-KT [nTPM]":"6.4","Cell RNA - HBF TERT88 [nTPM]":"6.2","Cell RNA - HDLM-2 [nTPM]":"64.4","Cell RNA - HEK 293 [nTPM]":"29.4","Cell RNA - HEL [nTPM]":"28.3","Cell RNA - HeLa [nTPM]":"1.9","Cell RNA - Hep G2 [nTPM]":"27.0","Cell RNA - HHSteC [nTPM]":"2.1","Cell RNA - HL-60 [nTPM]":"6.9","Cell RNA - HMC-1 [nTPM]":"25.7","Cell RNA - HSkMC [nTPM]":"6.0","Cell RNA - hTCEpi [nTPM]":"2.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.8","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"1.0","Cell RNA - HUVEC TERT2 [nTPM]":"40.8","Cell RNA - JURKAT [nTPM]":"20.6","Cell RNA - K-562 [nTPM]":"1.4","Cell RNA - Karpas-707 [nTPM]":"1.7","Cell RNA - LHCN-M2 [nTPM]":"1.8","Cell RNA - MCF7 [nTPM]":"24.9","Cell RNA - MOLT-4 [nTPM]":"33.4","Cell RNA - NB-4 [nTPM]":"16.7","Cell RNA - NTERA-2 [nTPM]":"12.7","Cell RNA - OE19 [nTPM]":"15.6","Cell RNA - PC-3 [nTPM]":"11.0","Cell RNA - REH [nTPM]":"13.1","Cell RNA - RH-30 [nTPM]":"28.4","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"3.6","Cell RNA - RT4 [nTPM]":"12.4","Cell RNA - SCLC-21H [nTPM]":"15.2","Cell RNA - SH-SY5Y [nTPM]":"11.9","Cell RNA - SiHa [nTPM]":"8.8","Cell RNA - SK-BR-3 [nTPM]":"15.0","Cell RNA - SK-MEL-30 [nTPM]":"71.9","Cell RNA - SuSa [nTPM]":"16.3","Cell RNA - T-47d [nTPM]":"9.9","Cell RNA - THP-1 [nTPM]":"6.6","Cell RNA - TIME [nTPM]":"66.7","Cell RNA - U-138 MG [nTPM]":"1.3","Cell RNA - U-2 OS [nTPM]":"3.5","Cell RNA - U-2197 [nTPM]":"4.1","Cell RNA - U-251 MG [nTPM]":"7.5","Cell RNA - U-266\/70 [nTPM]":"3.4","Cell RNA - U-266\/84 [nTPM]":"45.4","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"16.3","Cell RNA - U-937 [nTPM]":"17.1","Cell RNA - WM-115 [nTPM]":"10.5","Blood RNA - basophil [nTPM]":"3.2","Blood RNA - classical monocyte [nTPM]":"3.9","Blood RNA - eosinophil [nTPM]":"8.3","Blood RNA - gdT-cell [nTPM]":"8.5","Blood RNA - intermediate monocyte [nTPM]":"11.0","Blood RNA - MAIT T-cell [nTPM]":"10.7","Blood RNA - memory B-cell [nTPM]":"5.3","Blood RNA - memory CD4 T-cell [nTPM]":"7.2","Blood RNA - memory CD8 T-cell [nTPM]":"11.1","Blood RNA - myeloid DC [nTPM]":"1.8","Blood RNA - naive B-cell [nTPM]":"3.4","Blood RNA - naive CD4 T-cell [nTPM]":"8.2","Blood RNA - naive CD8 T-cell [nTPM]":"9.6","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"13.3","Blood RNA - non-classical monocyte [nTPM]":"8.6","Blood RNA - plasmacytoid DC [nTPM]":"3.3","Blood RNA - T-reg [nTPM]":"13.1","Blood RNA - total PBMC [nTPM]":"5.3","Brain RNA - amygdala [nTPM]":"3.6","Brain RNA - basal ganglia [nTPM]":"3.8","Brain RNA - cerebellum [nTPM]":"3.3","Brain RNA - cerebral cortex [nTPM]":"4.5","Brain RNA - hippocampal formation [nTPM]":"3.7","Brain RNA - hypothalamus [nTPM]":"3.9","Brain RNA - medulla oblongata [nTPM]":"5.1","Brain RNA - midbrain [nTPM]":"3.9","Brain RNA - pons [nTPM]":"4.2","Brain RNA - spinal cord [nTPM]":"7.0","Brain RNA - thalamus [nTPM]":"4.1","Brain RNA - white matter [nTPM]":"3.7","Single Cell Type RNA - Adipocytes [nTPM]":"9.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"2.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"6.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.6","Single Cell Type RNA - dendritic cells [nTPM]":"3.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"46.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.9","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.5","Single Cell Type RNA - Endothelial cells [nTPM]":"8.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"31.9","Single Cell Type RNA - Fibroblasts [nTPM]":"7.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"8.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"5.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.5","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"6.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.7","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"3.8","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.6","Single Cell Type RNA - Muller glia cells [nTPM]":"5.1","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.4","Single Cell Type RNA - Paneth cells [nTPM]":"3.2","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"2.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.5","Single Cell Type RNA - Spermatocytes [nTPM]":"10.9","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - T-cells [nTPM]":"5.0","Single Cell Type RNA - Theca cells [nTPM]":"5.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.8","Single Cell Type RNA - Urothelial cells [nTPM]":"2.9"},{"Gene":"USP27X","Gene synonym":["USP27"],"Ensembl":"ENSG00000273820","Gene description":"Ubiquitin specific peptidase 27 X-linked","Uniprot":["A6NNY8"],"Chromosome":"X","Position":"49879484-49882558","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"14.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"19.2","Alveolar cells type 2":"15.5","Bipolar cells":"15.8","Cytotrophoblasts":"44.5","Syncytiotrophoblasts":"26.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SuSa":"12.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077264"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA077264":"AB_2686831"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.58e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.14e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.31e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.6","Tissue RNA - adrenal gland [nTPM]":"2.5","Tissue RNA - amygdala [nTPM]":"6.0","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"6.2","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"2.0","Tissue RNA - cerebellum [nTPM]":"8.0","Tissue RNA - cerebral cortex [nTPM]":"5.8","Tissue RNA - cervix [nTPM]":"3.0","Tissue RNA - choroid plexus [nTPM]":"3.1","Tissue RNA - colon [nTPM]":"3.2","Tissue RNA - duodenum [nTPM]":"1.0","Tissue RNA - endometrium 1 [nTPM]":"3.9","Tissue RNA - epididymis [nTPM]":"2.9","Tissue RNA - esophagus [nTPM]":"1.6","Tissue RNA - fallopian tube [nTPM]":"3.5","Tissue RNA - gallbladder [nTPM]":"1.6","Tissue RNA - heart muscle [nTPM]":"1.8","Tissue RNA - hippocampal formation [nTPM]":"5.3","Tissue RNA - hypothalamus [nTPM]":"14.4","Tissue RNA - kidney [nTPM]":"2.7","Tissue RNA - liver [nTPM]":"1.8","Tissue RNA - lung [nTPM]":"2.7","Tissue RNA - lymph node [nTPM]":"1.7","Tissue RNA - medulla oblongata [nTPM]":"4.9","Tissue RNA - midbrain [nTPM]":"8.4","Tissue RNA - ovary [nTPM]":"6.3","Tissue RNA - pancreas [nTPM]":"2.6","Tissue RNA - parathyroid gland [nTPM]":"3.0","Tissue RNA - pituitary gland [nTPM]":"7.3","Tissue RNA - placenta [nTPM]":"11.7","Tissue RNA - pons [nTPM]":"5.9","Tissue RNA - prostate [nTPM]":"3.0","Tissue RNA - rectum [nTPM]":"1.4","Tissue RNA - retina [nTPM]":"3.8","Tissue RNA - salivary gland [nTPM]":"1.6","Tissue RNA - seminal vesicle [nTPM]":"2.8","Tissue RNA - skeletal muscle [nTPM]":"4.4","Tissue RNA - skin 1 [nTPM]":"2.1","Tissue RNA - small intestine [nTPM]":"2.1","Tissue RNA - smooth muscle [nTPM]":"2.8","Tissue RNA - spinal cord [nTPM]":"3.6","Tissue RNA - spleen [nTPM]":"1.8","Tissue RNA - stomach 1 [nTPM]":"2.4","Tissue RNA - testis [nTPM]":"1.3","Tissue RNA - thalamus [nTPM]":"10.5","Tissue RNA - thymus [nTPM]":"2.6","Tissue RNA - thyroid gland [nTPM]":"2.4","Tissue RNA - tongue [nTPM]":"2.1","Tissue RNA - tonsil [nTPM]":"1.7","Tissue RNA - urinary bladder [nTPM]":"3.0","Tissue RNA - vagina [nTPM]":"2.2","Tissue RNA - white matter [nTPM]":"4.4","Cell RNA - A-431 [nTPM]":"1.6","Cell RNA - A549 [nTPM]":"3.8","Cell RNA - AF22 [nTPM]":"4.2","Cell RNA - AN3-CA [nTPM]":"4.8","Cell RNA - ASC diff [nTPM]":"3.8","Cell RNA - ASC TERT1 [nTPM]":"3.1","Cell RNA - BEWO [nTPM]":"3.6","Cell RNA - BJ [nTPM]":"1.6","Cell RNA - BJ hTERT+ [nTPM]":"2.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.4","Cell RNA - CACO-2 [nTPM]":"6.9","Cell RNA - CAPAN-2 [nTPM]":"1.6","Cell RNA - Daudi [nTPM]":"0.9","Cell RNA - EFO-21 [nTPM]":"1.6","Cell RNA - fHDF\/TERT166 [nTPM]":"4.2","Cell RNA - GAMG [nTPM]":"6.0","Cell RNA - HaCaT [nTPM]":"2.6","Cell RNA - HAP1 [nTPM]":"6.0","Cell RNA - HBEC3-KT [nTPM]":"4.0","Cell RNA - HBF TERT88 [nTPM]":"2.6","Cell RNA - HDLM-2 [nTPM]":"2.0","Cell RNA - HEK 293 [nTPM]":"3.1","Cell RNA - HEL [nTPM]":"1.6","Cell RNA - HeLa [nTPM]":"1.1","Cell RNA - Hep G2 [nTPM]":"6.2","Cell RNA - HHSteC [nTPM]":"2.6","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"3.4","Cell RNA - HSkMC [nTPM]":"4.4","Cell RNA - hTCEpi [nTPM]":"2.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.6","Cell RNA - hTERT-HME1 [nTPM]":"2.6","Cell RNA - hTERT-RPE1 [nTPM]":"4.4","Cell RNA - HUVEC TERT2 [nTPM]":"2.5","Cell RNA - JURKAT [nTPM]":"4.2","Cell RNA - K-562 [nTPM]":"3.4","Cell RNA - Karpas-707 [nTPM]":"1.5","Cell RNA - LHCN-M2 [nTPM]":"2.9","Cell RNA - MCF7 [nTPM]":"3.7","Cell RNA - MOLT-4 [nTPM]":"2.5","Cell RNA - NB-4 [nTPM]":"1.2","Cell RNA - NTERA-2 [nTPM]":"4.8","Cell RNA - OE19 [nTPM]":"2.7","Cell RNA - PC-3 [nTPM]":"2.7","Cell RNA - REH [nTPM]":"2.7","Cell RNA - RH-30 [nTPM]":"3.7","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"2.9","Cell RNA - RT4 [nTPM]":"1.4","Cell RNA - SCLC-21H [nTPM]":"1.1","Cell RNA - SH-SY5Y [nTPM]":"3.2","Cell RNA - SiHa [nTPM]":"3.4","Cell RNA - SK-BR-3 [nTPM]":"3.0","Cell RNA - SK-MEL-30 [nTPM]":"4.0","Cell RNA - SuSa [nTPM]":"12.9","Cell RNA - T-47d [nTPM]":"3.5","Cell RNA - THP-1 [nTPM]":"1.1","Cell RNA - TIME [nTPM]":"1.9","Cell RNA - U-138 MG [nTPM]":"2.1","Cell RNA - U-2 OS [nTPM]":"4.3","Cell RNA - U-2197 [nTPM]":"3.8","Cell RNA - U-251 MG [nTPM]":"0.7","Cell RNA - U-266\/70 [nTPM]":"1.6","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.6","Cell RNA - U-87 MG [nTPM]":"2.5","Cell RNA - U-937 [nTPM]":"1.4","Cell RNA - WM-115 [nTPM]":"2.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"6.0","Brain RNA - basal ganglia [nTPM]":"6.2","Brain RNA - cerebellum [nTPM]":"8.0","Brain RNA - cerebral cortex [nTPM]":"5.8","Brain RNA - hippocampal formation [nTPM]":"5.3","Brain RNA - hypothalamus [nTPM]":"14.4","Brain RNA - medulla oblongata [nTPM]":"4.9","Brain RNA - midbrain [nTPM]":"8.4","Brain RNA - pons [nTPM]":"5.9","Brain RNA - spinal cord [nTPM]":"3.6","Brain RNA - thalamus [nTPM]":"10.5","Brain RNA - white matter [nTPM]":"4.4","Single Cell Type RNA - Adipocytes [nTPM]":"3.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"2.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"15.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"7.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"44.5","Single Cell Type RNA - dendritic cells [nTPM]":"1.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.1","Single Cell Type RNA - Endothelial cells [nTPM]":"5.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.6","Single Cell Type RNA - Fibroblasts [nTPM]":"2.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.1","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"4.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"1.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.0","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"1.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"1.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.5","Single Cell Type RNA - Muller glia cells [nTPM]":"8.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.5","Single Cell Type RNA - Peritubular cells [nTPM]":"3.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"26.1","Single Cell Type RNA - T-cells [nTPM]":"2.0","Single Cell Type RNA - Theca cells [nTPM]":"8.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.6","Single Cell Type RNA - Urothelial cells [nTPM]":"1.7"},{"Gene":"USP45","Gene synonym":["MGC14793"],"Ensembl":"ENSG00000123552","Gene description":"Ubiquitin specific peptidase 45","Uniprot":["Q70EL2"],"Chromosome":"6","Position":"99432325-99521728","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Disease variant","Leber congenital amaurosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"53.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"47.1","Inhibitory neurons":"44.4","Oligodendrocytes":"39.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"cerebellum":"53.5"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029602","HPA029604"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA029602":"AB_10600418","HPA029604":"AB_10602283"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.1","Tissue RNA - adrenal gland [nTPM]":"4.4","Tissue RNA - amygdala [nTPM]":"5.2","Tissue RNA - appendix [nTPM]":"4.9","Tissue RNA - basal ganglia [nTPM]":"5.8","Tissue RNA - bone marrow [nTPM]":"4.4","Tissue RNA - breast [nTPM]":"4.6","Tissue RNA - cerebellum [nTPM]":"53.5","Tissue RNA - cerebral cortex [nTPM]":"9.4","Tissue RNA - cervix [nTPM]":"4.3","Tissue RNA - choroid plexus [nTPM]":"3.8","Tissue RNA - colon [nTPM]":"5.3","Tissue RNA - duodenum [nTPM]":"7.3","Tissue RNA - endometrium 1 [nTPM]":"5.1","Tissue RNA - epididymis [nTPM]":"4.8","Tissue RNA - esophagus [nTPM]":"5.3","Tissue RNA - fallopian tube [nTPM]":"4.0","Tissue RNA - gallbladder [nTPM]":"6.2","Tissue RNA - heart muscle [nTPM]":"6.2","Tissue RNA - hippocampal formation [nTPM]":"5.8","Tissue RNA - hypothalamus [nTPM]":"6.3","Tissue RNA - kidney [nTPM]":"6.3","Tissue RNA - liver [nTPM]":"4.2","Tissue RNA - lung [nTPM]":"3.7","Tissue RNA - lymph node [nTPM]":"7.4","Tissue RNA - medulla oblongata [nTPM]":"6.0","Tissue RNA - midbrain [nTPM]":"7.7","Tissue RNA - ovary [nTPM]":"4.5","Tissue RNA - pancreas [nTPM]":"4.0","Tissue RNA - parathyroid gland [nTPM]":"4.5","Tissue RNA - pituitary gland [nTPM]":"3.6","Tissue RNA - placenta [nTPM]":"5.2","Tissue RNA - pons [nTPM]":"8.2","Tissue RNA - prostate [nTPM]":"5.1","Tissue RNA - rectum [nTPM]":"6.7","Tissue RNA - retina [nTPM]":"6.7","Tissue RNA - salivary gland [nTPM]":"4.0","Tissue RNA - seminal vesicle [nTPM]":"4.2","Tissue RNA - skeletal muscle [nTPM]":"6.0","Tissue RNA - skin 1 [nTPM]":"6.3","Tissue RNA - small intestine [nTPM]":"5.8","Tissue RNA - smooth muscle [nTPM]":"4.5","Tissue RNA - spinal cord [nTPM]":"5.3","Tissue RNA - spleen [nTPM]":"4.6","Tissue RNA - stomach 1 [nTPM]":"4.4","Tissue RNA - testis [nTPM]":"3.3","Tissue RNA - thalamus [nTPM]":"6.2","Tissue RNA - thymus [nTPM]":"3.1","Tissue RNA - thyroid gland [nTPM]":"5.3","Tissue RNA - tongue [nTPM]":"5.5","Tissue RNA - tonsil [nTPM]":"5.2","Tissue RNA - urinary bladder [nTPM]":"4.3","Tissue RNA - vagina [nTPM]":"3.8","Tissue RNA - white matter [nTPM]":"9.0","Cell RNA - A-431 [nTPM]":"5.9","Cell RNA - A549 [nTPM]":"4.0","Cell RNA - AF22 [nTPM]":"8.1","Cell RNA - AN3-CA [nTPM]":"11.2","Cell RNA - ASC diff [nTPM]":"14.3","Cell RNA - ASC TERT1 [nTPM]":"13.5","Cell RNA - BEWO [nTPM]":"8.7","Cell RNA - BJ [nTPM]":"10.3","Cell RNA - BJ hTERT+ [nTPM]":"11.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.7","Cell RNA - CACO-2 [nTPM]":"8.2","Cell RNA - CAPAN-2 [nTPM]":"6.4","Cell RNA - Daudi [nTPM]":"15.2","Cell RNA - EFO-21 [nTPM]":"7.3","Cell RNA - fHDF\/TERT166 [nTPM]":"10.3","Cell RNA - GAMG [nTPM]":"11.9","Cell RNA - HaCaT [nTPM]":"7.7","Cell RNA - HAP1 [nTPM]":"12.1","Cell RNA - HBEC3-KT [nTPM]":"9.8","Cell RNA - HBF TERT88 [nTPM]":"13.9","Cell RNA - HDLM-2 [nTPM]":"12.2","Cell RNA - HEK 293 [nTPM]":"12.0","Cell RNA - HEL [nTPM]":"15.2","Cell RNA - HeLa [nTPM]":"8.4","Cell RNA - Hep G2 [nTPM]":"6.7","Cell RNA - HHSteC [nTPM]":"11.4","Cell RNA - HL-60 [nTPM]":"14.2","Cell RNA - HMC-1 [nTPM]":"8.3","Cell RNA - HSkMC [nTPM]":"15.3","Cell RNA - hTCEpi [nTPM]":"7.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.2","Cell RNA - hTERT-HME1 [nTPM]":"15.5","Cell RNA - hTERT-RPE1 [nTPM]":"10.7","Cell RNA - HUVEC TERT2 [nTPM]":"15.4","Cell RNA - JURKAT [nTPM]":"13.8","Cell RNA - K-562 [nTPM]":"37.2","Cell RNA - Karpas-707 [nTPM]":"14.8","Cell RNA - LHCN-M2 [nTPM]":"9.6","Cell RNA - MCF7 [nTPM]":"5.5","Cell RNA - MOLT-4 [nTPM]":"4.5","Cell RNA - NB-4 [nTPM]":"13.3","Cell RNA - NTERA-2 [nTPM]":"12.8","Cell RNA - OE19 [nTPM]":"9.1","Cell RNA - PC-3 [nTPM]":"8.9","Cell RNA - REH [nTPM]":"6.8","Cell RNA - RH-30 [nTPM]":"5.9","Cell RNA - RPMI-8226 [nTPM]":"8.9","Cell RNA - RPTEC TERT1 [nTPM]":"13.8","Cell RNA - RT4 [nTPM]":"6.8","Cell RNA - SCLC-21H [nTPM]":"11.3","Cell RNA - SH-SY5Y [nTPM]":"9.2","Cell RNA - SiHa [nTPM]":"7.0","Cell RNA - SK-BR-3 [nTPM]":"9.1","Cell RNA - SK-MEL-30 [nTPM]":"7.8","Cell RNA - SuSa [nTPM]":"10.0","Cell RNA - T-47d [nTPM]":"4.9","Cell RNA - THP-1 [nTPM]":"6.8","Cell RNA - TIME [nTPM]":"15.5","Cell RNA - U-138 MG [nTPM]":"5.5","Cell RNA - U-2 OS [nTPM]":"7.1","Cell RNA - U-2197 [nTPM]":"8.1","Cell RNA - U-251 MG [nTPM]":"15.5","Cell RNA - U-266\/70 [nTPM]":"6.3","Cell RNA - U-266\/84 [nTPM]":"6.2","Cell RNA - U-698 [nTPM]":"29.1","Cell RNA - U-87 MG [nTPM]":"9.8","Cell RNA - U-937 [nTPM]":"13.1","Cell RNA - WM-115 [nTPM]":"10.1","Blood RNA - basophil [nTPM]":"2.9","Blood RNA - classical monocyte [nTPM]":"1.4","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"3.2","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"4.2","Blood RNA - memory B-cell [nTPM]":"5.3","Blood RNA - memory CD4 T-cell [nTPM]":"2.7","Blood RNA - memory CD8 T-cell [nTPM]":"4.0","Blood RNA - myeloid DC [nTPM]":"2.4","Blood RNA - naive B-cell [nTPM]":"6.7","Blood RNA - naive CD4 T-cell [nTPM]":"1.9","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"1.9","Blood RNA - non-classical monocyte [nTPM]":"2.0","Blood RNA - plasmacytoid DC [nTPM]":"3.6","Blood RNA - T-reg [nTPM]":"2.6","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"5.2","Brain RNA - basal ganglia [nTPM]":"5.8","Brain RNA - cerebellum [nTPM]":"53.5","Brain RNA - cerebral cortex [nTPM]":"9.4","Brain RNA - hippocampal formation [nTPM]":"5.8","Brain RNA - hypothalamus [nTPM]":"6.3","Brain RNA - medulla oblongata [nTPM]":"6.0","Brain RNA - midbrain [nTPM]":"7.7","Brain RNA - pons [nTPM]":"8.2","Brain RNA - spinal cord [nTPM]":"5.3","Brain RNA - thalamus [nTPM]":"6.2","Brain RNA - white matter [nTPM]":"9.0","Single Cell Type RNA - Adipocytes [nTPM]":"13.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.8","Single Cell Type RNA - Astrocytes [nTPM]":"22.5","Single Cell Type RNA - B-cells [nTPM]":"13.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"10.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"4.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.4","Single Cell Type RNA - dendritic cells [nTPM]":"7.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.3","Single Cell Type RNA - Early spermatids [nTPM]":"15.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.3","Single Cell Type RNA - Endothelial cells [nTPM]":"7.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"4.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"47.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.6","Single Cell Type RNA - Fibroblasts [nTPM]":"7.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.3","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"5.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"4.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.0","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"44.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.9","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"4.8","Single Cell Type RNA - Langerhans cells [nTPM]":"2.6","Single Cell Type RNA - Late spermatids [nTPM]":"10.2","Single Cell Type RNA - Leydig cells [nTPM]":"13.1","Single Cell Type RNA - Macrophages [nTPM]":"4.6","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"22.5","Single Cell Type RNA - monocytes [nTPM]":"10.0","Single Cell Type RNA - Muller glia cells [nTPM]":"5.4","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"32.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"39.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.0","Single Cell Type RNA - Paneth cells [nTPM]":"3.1","Single Cell Type RNA - Peritubular cells [nTPM]":"8.6","Single Cell Type RNA - Plasma cells [nTPM]":"6.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.7","Single Cell Type RNA - Spermatocytes [nTPM]":"1.9","Single Cell Type RNA - Spermatogonia [nTPM]":"7.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.4","Single Cell Type RNA - T-cells [nTPM]":"7.1","Single Cell Type RNA - Theca cells [nTPM]":"5.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.3","Single Cell Type RNA - Urothelial cells [nTPM]":"6.9"},{"Gene":"USP6","Gene synonym":["HRP1","Tre-2","TRE17","Tre2","TRESMCR"],"Ensembl":"ENSG00000129204","Gene description":"Ubiquitin specific peptidase 6","Uniprot":["P35125"],"Chromosome":"17","Position":"5116032-5175034","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Calmodulin-binding","Hydrolase","Protease","Thiol protease"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"skeletal muscle":"19.6","testis":"13.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"24.4","Spermatocytes":"26.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"14","RNA cancer specific FPKM":{"testis cancer":"2.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046969"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 37: Myocytes - Muscle contraction","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA046969":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.91e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-4"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.7","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"1.4","Tissue RNA - choroid plexus [nTPM]":"1.5","Tissue RNA - colon [nTPM]":"0.8","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.9","Tissue RNA - epididymis [nTPM]":"0.7","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"0.7","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"2.6","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.6","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"0.6","Tissue RNA - prostate [nTPM]":"0.6","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"2.5","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"19.6","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.9","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"13.4","Tissue RNA - thalamus [nTPM]":"0.5","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.9","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"0.9","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.7","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.6","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.5","Brain RNA - white matter [nTPM]":"0.9","Single Cell Type RNA - Adipocytes [nTPM]":"2.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"8.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"3.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.6","Single Cell Type RNA - dendritic cells [nTPM]":"1.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"24.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.1","Single Cell Type RNA - Endothelial cells [nTPM]":"3.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.8","Single Cell Type RNA - Fibroblasts [nTPM]":"1.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"3.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.7","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"5.4","Single Cell Type RNA - Langerhans cells [nTPM]":"6.4","Single Cell Type RNA - Late spermatids [nTPM]":"13.5","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"3.1","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"3.2","Single Cell Type RNA - Muller glia cells [nTPM]":"5.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.7","Single Cell Type RNA - Spermatocytes [nTPM]":"26.9","Single Cell Type RNA - Spermatogonia [nTPM]":"11.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"0.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"1.1"},{"Gene":"USP8","Gene synonym":["HumORF8","KIAA0055","SPG59","UBPY"],"Ensembl":"ENSG00000138592","Gene description":"Ubiquitin specific peptidase 8","Uniprot":["P40818"],"Chromosome":"15","Position":"50424380-50514421","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","Ubl conjugation pathway"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Cancer-related genes","Cushing syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050215"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA050215":"AB_2681054"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.29e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Tissue RNA - adipose tissue [nTPM]":"20.3","Tissue RNA - adrenal gland [nTPM]":"18.8","Tissue RNA - amygdala [nTPM]":"11.5","Tissue RNA - appendix [nTPM]":"21.1","Tissue RNA - basal ganglia [nTPM]":"11.0","Tissue RNA - bone marrow [nTPM]":"27.6","Tissue RNA - breast [nTPM]":"19.6","Tissue RNA - cerebellum [nTPM]":"14.4","Tissue RNA - cerebral cortex [nTPM]":"13.3","Tissue RNA - cervix [nTPM]":"20.5","Tissue RNA - choroid plexus [nTPM]":"18.1","Tissue RNA - colon [nTPM]":"21.5","Tissue RNA - duodenum [nTPM]":"26.7","Tissue RNA - endometrium 1 [nTPM]":"19.1","Tissue RNA - epididymis [nTPM]":"10.4","Tissue RNA - esophagus [nTPM]":"20.7","Tissue RNA - fallopian tube [nTPM]":"18.5","Tissue RNA - gallbladder [nTPM]":"16.4","Tissue RNA - heart muscle [nTPM]":"15.1","Tissue RNA - hippocampal formation [nTPM]":"9.1","Tissue RNA - hypothalamus [nTPM]":"14.6","Tissue RNA - kidney [nTPM]":"27.0","Tissue RNA - liver [nTPM]":"28.1","Tissue RNA - lung [nTPM]":"19.5","Tissue RNA - lymph node [nTPM]":"19.0","Tissue RNA - medulla oblongata [nTPM]":"14.1","Tissue RNA - midbrain [nTPM]":"13.1","Tissue RNA - ovary [nTPM]":"19.9","Tissue RNA - pancreas [nTPM]":"17.4","Tissue RNA - parathyroid gland [nTPM]":"45.1","Tissue RNA - pituitary gland [nTPM]":"10.6","Tissue RNA - placenta [nTPM]":"20.3","Tissue RNA - pons [nTPM]":"12.5","Tissue RNA - prostate [nTPM]":"17.0","Tissue RNA - rectum [nTPM]":"20.8","Tissue RNA - retina [nTPM]":"22.2","Tissue RNA - salivary gland [nTPM]":"19.8","Tissue RNA - seminal vesicle [nTPM]":"17.2","Tissue RNA - skeletal muscle [nTPM]":"17.6","Tissue RNA - skin 1 [nTPM]":"14.2","Tissue RNA - small intestine [nTPM]":"24.4","Tissue RNA - smooth muscle [nTPM]":"18.4","Tissue RNA - spinal cord [nTPM]":"11.5","Tissue RNA - spleen [nTPM]":"18.7","Tissue RNA - stomach 1 [nTPM]":"22.5","Tissue RNA - testis [nTPM]":"32.0","Tissue RNA - thalamus [nTPM]":"13.6","Tissue RNA - thymus [nTPM]":"20.9","Tissue RNA - thyroid gland [nTPM]":"25.4","Tissue RNA - tongue [nTPM]":"22.7","Tissue RNA - tonsil [nTPM]":"24.3","Tissue RNA - urinary bladder [nTPM]":"20.0","Tissue RNA - vagina [nTPM]":"12.6","Tissue RNA - white matter [nTPM]":"13.2","Cell RNA - A-431 [nTPM]":"30.6","Cell RNA - A549 [nTPM]":"35.8","Cell RNA - AF22 [nTPM]":"23.7","Cell RNA - AN3-CA [nTPM]":"41.1","Cell RNA - ASC diff [nTPM]":"32.3","Cell RNA - ASC TERT1 [nTPM]":"44.3","Cell RNA - BEWO [nTPM]":"31.0","Cell RNA - BJ [nTPM]":"45.7","Cell RNA - BJ hTERT+ [nTPM]":"43.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"35.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"40.4","Cell RNA - CACO-2 [nTPM]":"19.5","Cell RNA - CAPAN-2 [nTPM]":"17.7","Cell RNA - Daudi [nTPM]":"28.8","Cell RNA - EFO-21 [nTPM]":"35.0","Cell RNA - fHDF\/TERT166 [nTPM]":"43.5","Cell RNA - GAMG [nTPM]":"46.6","Cell RNA - HaCaT [nTPM]":"57.8","Cell RNA - HAP1 [nTPM]":"28.8","Cell RNA - HBEC3-KT [nTPM]":"28.3","Cell RNA - HBF TERT88 [nTPM]":"39.9","Cell RNA - HDLM-2 [nTPM]":"27.2","Cell RNA - HEK 293 [nTPM]":"19.3","Cell RNA - HEL [nTPM]":"52.9","Cell RNA - HeLa [nTPM]":"31.9","Cell RNA - Hep G2 [nTPM]":"27.3","Cell RNA - HHSteC [nTPM]":"35.9","Cell RNA - HL-60 [nTPM]":"34.3","Cell RNA - HMC-1 [nTPM]":"34.4","Cell RNA - HSkMC [nTPM]":"32.4","Cell RNA - hTCEpi [nTPM]":"36.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.0","Cell RNA - hTERT-HME1 [nTPM]":"55.8","Cell RNA - hTERT-RPE1 [nTPM]":"37.0","Cell RNA - HUVEC TERT2 [nTPM]":"36.3","Cell RNA - JURKAT [nTPM]":"23.3","Cell RNA - K-562 [nTPM]":"28.4","Cell RNA - Karpas-707 [nTPM]":"36.8","Cell RNA - LHCN-M2 [nTPM]":"32.9","Cell RNA - MCF7 [nTPM]":"45.9","Cell RNA - MOLT-4 [nTPM]":"26.6","Cell RNA - NB-4 [nTPM]":"12.0","Cell RNA - NTERA-2 [nTPM]":"28.5","Cell RNA - OE19 [nTPM]":"32.6","Cell RNA - PC-3 [nTPM]":"17.1","Cell RNA - REH [nTPM]":"24.1","Cell RNA - RH-30 [nTPM]":"39.1","Cell RNA - RPMI-8226 [nTPM]":"45.8","Cell RNA - RPTEC TERT1 [nTPM]":"29.5","Cell RNA - RT4 [nTPM]":"61.3","Cell RNA - SCLC-21H [nTPM]":"29.1","Cell RNA - SH-SY5Y [nTPM]":"23.8","Cell RNA - SiHa [nTPM]":"42.5","Cell RNA - SK-BR-3 [nTPM]":"55.9","Cell RNA - SK-MEL-30 [nTPM]":"57.4","Cell RNA - SuSa [nTPM]":"48.9","Cell RNA - T-47d [nTPM]":"35.8","Cell RNA - THP-1 [nTPM]":"36.9","Cell RNA - TIME [nTPM]":"45.0","Cell RNA - U-138 MG [nTPM]":"41.1","Cell RNA - U-2 OS [nTPM]":"24.1","Cell RNA - U-2197 [nTPM]":"122.7","Cell RNA - U-251 MG [nTPM]":"52.7","Cell RNA - U-266\/70 [nTPM]":"28.5","Cell RNA - U-266\/84 [nTPM]":"69.8","Cell RNA - U-698 [nTPM]":"32.4","Cell RNA - U-87 MG [nTPM]":"30.6","Cell RNA - U-937 [nTPM]":"65.6","Cell RNA - WM-115 [nTPM]":"40.1","Blood RNA - basophil [nTPM]":"114.6","Blood RNA - classical monocyte [nTPM]":"27.7","Blood RNA - eosinophil [nTPM]":"50.1","Blood RNA - gdT-cell [nTPM]":"21.4","Blood RNA - intermediate monocyte [nTPM]":"26.1","Blood RNA - MAIT T-cell [nTPM]":"22.1","Blood RNA - memory B-cell [nTPM]":"37.3","Blood RNA - memory CD4 T-cell [nTPM]":"22.9","Blood RNA - memory CD8 T-cell [nTPM]":"23.3","Blood RNA - myeloid DC [nTPM]":"22.7","Blood RNA - naive B-cell [nTPM]":"34.3","Blood RNA - naive CD4 T-cell [nTPM]":"24.0","Blood RNA - naive CD8 T-cell [nTPM]":"21.2","Blood RNA - neutrophil [nTPM]":"47.9","Blood RNA - NK-cell [nTPM]":"22.1","Blood RNA - non-classical monocyte [nTPM]":"35.0","Blood RNA - plasmacytoid DC [nTPM]":"20.5","Blood RNA - T-reg [nTPM]":"20.0","Blood RNA - total PBMC [nTPM]":"16.0","Brain RNA - amygdala [nTPM]":"11.5","Brain RNA - basal ganglia [nTPM]":"11.0","Brain RNA - cerebellum [nTPM]":"14.4","Brain RNA - cerebral cortex [nTPM]":"13.3","Brain RNA - hippocampal formation [nTPM]":"9.1","Brain RNA - hypothalamus [nTPM]":"14.6","Brain RNA - medulla oblongata [nTPM]":"14.1","Brain RNA - midbrain [nTPM]":"13.1","Brain RNA - pons [nTPM]":"12.5","Brain RNA - spinal cord [nTPM]":"11.5","Brain RNA - thalamus [nTPM]":"13.6","Brain RNA - white matter [nTPM]":"13.2","Single Cell Type RNA - Adipocytes [nTPM]":"63.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"96.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"130.8","Single Cell Type RNA - Astrocytes [nTPM]":"36.2","Single Cell Type RNA - B-cells [nTPM]":"101.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"28.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"40.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"47.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"35.9","Single Cell Type RNA - Bipolar cells [nTPM]":"54.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"41.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"40.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"69.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"51.5","Single Cell Type RNA - Club cells [nTPM]":"72.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"47.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"68.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"59.0","Single Cell Type RNA - dendritic cells [nTPM]":"92.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"79.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"25.4","Single Cell Type RNA - Ductal cells [nTPM]":"53.7","Single Cell Type RNA - Early spermatids [nTPM]":"153.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"91.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"79.7","Single Cell Type RNA - Endothelial cells [nTPM]":"53.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"53.3","Single Cell Type RNA - Erythroid cells [nTPM]":"36.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"41.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"51.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"45.4","Single Cell Type RNA - Fibroblasts [nTPM]":"55.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"58.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"65.6","Single Cell Type RNA - granulocytes [nTPM]":"86.7","Single Cell Type RNA - Granulosa cells [nTPM]":"48.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"51.0","Single Cell Type RNA - Hepatocytes [nTPM]":"56.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"45.4","Single Cell Type RNA - Horizontal cells [nTPM]":"33.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"44.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"68.7","Single Cell Type RNA - Ionocytes [nTPM]":"36.7","Single Cell Type RNA - Kupffer cells [nTPM]":"73.2","Single Cell Type RNA - Langerhans cells [nTPM]":"38.2","Single Cell Type RNA - Late spermatids [nTPM]":"28.4","Single Cell Type RNA - Leydig cells [nTPM]":"53.7","Single Cell Type RNA - Macrophages [nTPM]":"77.6","Single Cell Type RNA - Melanocytes [nTPM]":"40.9","Single Cell Type RNA - Microglial cells [nTPM]":"46.9","Single Cell Type RNA - monocytes [nTPM]":"85.3","Single Cell Type RNA - Muller glia cells [nTPM]":"45.5","Single Cell Type RNA - NK-cells [nTPM]":"72.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"34.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"46.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"57.3","Single Cell Type RNA - Paneth cells [nTPM]":"58.2","Single Cell Type RNA - Peritubular cells [nTPM]":"61.7","Single Cell Type RNA - Plasma cells [nTPM]":"87.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"51.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"88.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"49.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"114.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"74.2","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"108.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"56.2","Single Cell Type RNA - Spermatocytes [nTPM]":"140.5","Single Cell Type RNA - Spermatogonia [nTPM]":"54.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"39.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"41.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"105.2","Single Cell Type RNA - T-cells [nTPM]":"72.6","Single Cell Type RNA - Theca cells [nTPM]":"77.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"64.8","Single Cell Type RNA - Urothelial cells [nTPM]":"55.3"},{"Gene":"USP9X","Gene synonym":["DFFRX","FAF","MRX99"],"Ensembl":"ENSG00000124486","Gene description":"Ubiquitin specific peptidase 9 X-linked","Uniprot":["Q93008"],"Chromosome":"X","Position":"41085445-41236579","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Biological rhythms","Cell cycle","Cell division","Chromosome partition","Mitosis","Ubl conjugation pathway"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011618","HPA047417","CAB070164"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"24000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB011618":"AB_470860","CAB070164":"AB_10011071","HPA047417":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Tissue RNA - adipose tissue [nTPM]":"16.4","Tissue RNA - adrenal gland [nTPM]":"16.8","Tissue RNA - amygdala [nTPM]":"11.9","Tissue RNA - appendix [nTPM]":"14.3","Tissue RNA - basal ganglia [nTPM]":"13.9","Tissue RNA - bone marrow [nTPM]":"18.2","Tissue RNA - breast [nTPM]":"14.2","Tissue RNA - cerebellum [nTPM]":"12.7","Tissue RNA - cerebral cortex [nTPM]":"12.8","Tissue RNA - cervix [nTPM]":"15.3","Tissue RNA - choroid plexus [nTPM]":"14.3","Tissue RNA - colon [nTPM]":"14.8","Tissue RNA - duodenum [nTPM]":"13.6","Tissue RNA - endometrium 1 [nTPM]":"15.4","Tissue RNA - epididymis [nTPM]":"14.9","Tissue RNA - esophagus [nTPM]":"14.1","Tissue RNA - fallopian tube [nTPM]":"16.0","Tissue RNA - gallbladder [nTPM]":"13.0","Tissue RNA - heart muscle [nTPM]":"15.3","Tissue RNA - hippocampal formation [nTPM]":"14.3","Tissue RNA - hypothalamus [nTPM]":"13.2","Tissue RNA - kidney [nTPM]":"17.8","Tissue RNA - liver [nTPM]":"33.9","Tissue RNA - lung [nTPM]":"14.4","Tissue RNA - lymph node [nTPM]":"15.8","Tissue RNA - medulla oblongata [nTPM]":"12.2","Tissue RNA - midbrain [nTPM]":"13.1","Tissue RNA - ovary [nTPM]":"13.4","Tissue RNA - pancreas [nTPM]":"16.0","Tissue RNA - parathyroid gland [nTPM]":"30.0","Tissue RNA - pituitary gland [nTPM]":"10.2","Tissue RNA - placenta [nTPM]":"18.4","Tissue RNA - pons [nTPM]":"13.8","Tissue RNA - prostate [nTPM]":"12.3","Tissue RNA - rectum [nTPM]":"13.7","Tissue RNA - retina [nTPM]":"22.0","Tissue RNA - salivary gland [nTPM]":"11.5","Tissue RNA - seminal vesicle [nTPM]":"15.3","Tissue RNA - skeletal muscle [nTPM]":"39.1","Tissue RNA - skin 1 [nTPM]":"13.8","Tissue RNA - small intestine [nTPM]":"14.3","Tissue RNA - smooth muscle [nTPM]":"16.3","Tissue RNA - spinal cord [nTPM]":"12.5","Tissue RNA - spleen [nTPM]":"13.3","Tissue RNA - stomach 1 [nTPM]":"13.8","Tissue RNA - testis [nTPM]":"17.5","Tissue RNA - thalamus [nTPM]":"12.8","Tissue RNA - thymus [nTPM]":"18.8","Tissue RNA - thyroid gland [nTPM]":"19.5","Tissue RNA - tongue [nTPM]":"28.4","Tissue RNA - tonsil [nTPM]":"16.2","Tissue RNA - urinary bladder [nTPM]":"15.0","Tissue RNA - vagina [nTPM]":"12.6","Tissue RNA - white matter [nTPM]":"16.4","Cell RNA - A-431 [nTPM]":"38.6","Cell RNA - A549 [nTPM]":"44.2","Cell RNA - AF22 [nTPM]":"39.1","Cell RNA - AN3-CA [nTPM]":"40.2","Cell RNA - ASC diff [nTPM]":"33.0","Cell RNA - ASC TERT1 [nTPM]":"32.7","Cell RNA - BEWO [nTPM]":"8.8","Cell RNA - BJ [nTPM]":"21.5","Cell RNA - BJ hTERT+ [nTPM]":"28.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"27.5","Cell RNA - CACO-2 [nTPM]":"21.1","Cell RNA - CAPAN-2 [nTPM]":"16.9","Cell RNA - Daudi [nTPM]":"25.7","Cell RNA - EFO-21 [nTPM]":"11.5","Cell RNA - fHDF\/TERT166 [nTPM]":"48.5","Cell RNA - GAMG [nTPM]":"71.3","Cell RNA - HaCaT [nTPM]":"25.3","Cell RNA - HAP1 [nTPM]":"67.1","Cell RNA - HBEC3-KT [nTPM]":"39.7","Cell RNA - HBF TERT88 [nTPM]":"39.7","Cell RNA - HDLM-2 [nTPM]":"32.0","Cell RNA - HEK 293 [nTPM]":"50.5","Cell RNA - HEL [nTPM]":"29.3","Cell RNA - HeLa [nTPM]":"41.3","Cell RNA - Hep G2 [nTPM]":"19.9","Cell RNA - HHSteC [nTPM]":"27.6","Cell RNA - HL-60 [nTPM]":"26.4","Cell RNA - HMC-1 [nTPM]":"21.0","Cell RNA - HSkMC [nTPM]":"29.3","Cell RNA - hTCEpi [nTPM]":"17.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"56.4","Cell RNA - hTERT-HME1 [nTPM]":"53.4","Cell RNA - hTERT-RPE1 [nTPM]":"35.5","Cell RNA - HUVEC TERT2 [nTPM]":"37.2","Cell RNA - JURKAT [nTPM]":"17.1","Cell RNA - K-562 [nTPM]":"36.0","Cell RNA - Karpas-707 [nTPM]":"20.3","Cell RNA - LHCN-M2 [nTPM]":"38.6","Cell RNA - MCF7 [nTPM]":"29.1","Cell RNA - MOLT-4 [nTPM]":"18.8","Cell RNA - NB-4 [nTPM]":"12.7","Cell RNA - NTERA-2 [nTPM]":"42.6","Cell RNA - OE19 [nTPM]":"14.1","Cell RNA - PC-3 [nTPM]":"24.7","Cell RNA - REH [nTPM]":"20.3","Cell RNA - RH-30 [nTPM]":"51.8","Cell RNA - RPMI-8226 [nTPM]":"16.9","Cell RNA - RPTEC TERT1 [nTPM]":"24.7","Cell RNA - RT4 [nTPM]":"30.7","Cell RNA - SCLC-21H [nTPM]":"22.2","Cell RNA - SH-SY5Y [nTPM]":"20.8","Cell RNA - SiHa [nTPM]":"89.0","Cell RNA - SK-BR-3 [nTPM]":"26.7","Cell RNA - SK-MEL-30 [nTPM]":"26.0","Cell RNA - SuSa [nTPM]":"69.8","Cell RNA - T-47d [nTPM]":"24.3","Cell RNA - THP-1 [nTPM]":"16.2","Cell RNA - TIME [nTPM]":"40.2","Cell RNA - U-138 MG [nTPM]":"36.6","Cell RNA - U-2 OS [nTPM]":"27.6","Cell RNA - U-2197 [nTPM]":"34.6","Cell RNA - U-251 MG [nTPM]":"24.0","Cell RNA - U-266\/70 [nTPM]":"19.1","Cell RNA - U-266\/84 [nTPM]":"22.3","Cell RNA - U-698 [nTPM]":"30.9","Cell RNA - U-87 MG [nTPM]":"26.4","Cell RNA - U-937 [nTPM]":"12.1","Cell RNA - WM-115 [nTPM]":"18.5","Blood RNA - basophil [nTPM]":"1.7","Blood RNA - classical monocyte [nTPM]":"2.3","Blood RNA - eosinophil [nTPM]":"3.0","Blood RNA - gdT-cell [nTPM]":"2.5","Blood RNA - intermediate monocyte [nTPM]":"1.9","Blood RNA - MAIT T-cell [nTPM]":"3.6","Blood RNA - memory B-cell [nTPM]":"2.8","Blood RNA - memory CD4 T-cell [nTPM]":"3.0","Blood RNA - memory CD8 T-cell [nTPM]":"2.7","Blood RNA - myeloid DC [nTPM]":"2.6","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"3.0","Blood RNA - naive CD8 T-cell [nTPM]":"2.8","Blood RNA - neutrophil [nTPM]":"6.4","Blood RNA - NK-cell [nTPM]":"2.5","Blood RNA - non-classical monocyte [nTPM]":"2.5","Blood RNA - plasmacytoid DC [nTPM]":"2.1","Blood RNA - T-reg [nTPM]":"2.8","Blood RNA - total PBMC [nTPM]":"1.5","Brain RNA - amygdala [nTPM]":"11.9","Brain RNA - basal ganglia [nTPM]":"13.9","Brain RNA - cerebellum [nTPM]":"12.7","Brain RNA - cerebral cortex [nTPM]":"12.8","Brain RNA - hippocampal formation [nTPM]":"14.3","Brain RNA - hypothalamus [nTPM]":"13.2","Brain RNA - medulla oblongata [nTPM]":"12.2","Brain RNA - midbrain [nTPM]":"13.1","Brain RNA - pons [nTPM]":"13.8","Brain RNA - spinal cord [nTPM]":"12.5","Brain RNA - thalamus [nTPM]":"12.8","Brain RNA - white matter [nTPM]":"16.4","Single Cell Type RNA - Adipocytes [nTPM]":"38.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"35.1","Single Cell Type RNA - Astrocytes [nTPM]":"48.0","Single Cell Type RNA - B-cells [nTPM]":"42.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"48.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"30.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"55.2","Single Cell Type RNA - Bipolar cells [nTPM]":"38.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"41.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"29.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"83.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"54.3","Single Cell Type RNA - Club cells [nTPM]":"37.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"39.6","Single Cell Type RNA - dendritic cells [nTPM]":"46.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"58.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"28.4","Single Cell Type RNA - Early spermatids [nTPM]":"14.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"85.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"56.9","Single Cell Type RNA - Endothelial cells [nTPM]":"43.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"26.9","Single Cell Type RNA - Erythroid cells [nTPM]":"41.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"84.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"25.4","Single Cell Type RNA - Fibroblasts [nTPM]":"41.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"41.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"136.9","Single Cell Type RNA - granulocytes [nTPM]":"25.9","Single Cell Type RNA - Granulosa cells [nTPM]":"58.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"45.7","Single Cell Type RNA - Hepatocytes [nTPM]":"62.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"32.6","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"86.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"39.1","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"47.8","Single Cell Type RNA - Langerhans cells [nTPM]":"42.1","Single Cell Type RNA - Late spermatids [nTPM]":"15.4","Single Cell Type RNA - Leydig cells [nTPM]":"33.2","Single Cell Type RNA - Macrophages [nTPM]":"55.5","Single Cell Type RNA - Melanocytes [nTPM]":"33.8","Single Cell Type RNA - Microglial cells [nTPM]":"67.5","Single Cell Type RNA - monocytes [nTPM]":"44.6","Single Cell Type RNA - Muller glia cells [nTPM]":"31.3","Single Cell Type RNA - NK-cells [nTPM]":"30.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"74.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"108.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"32.6","Single Cell Type RNA - Paneth cells [nTPM]":"40.1","Single Cell Type RNA - Peritubular cells [nTPM]":"49.2","Single Cell Type RNA - Plasma cells [nTPM]":"38.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"35.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"47.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"35.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"31.2","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"70.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"48.3","Single Cell Type RNA - Spermatocytes [nTPM]":"86.4","Single Cell Type RNA - Spermatogonia [nTPM]":"82.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"55.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"55.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"46.7","Single Cell Type RNA - T-cells [nTPM]":"42.4","Single Cell Type RNA - Theca cells [nTPM]":"45.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"38.0","Single Cell Type RNA - Urothelial cells [nTPM]":"40.2"},{"Gene":"USP9Y","Gene synonym":["AZFA","DFFRY"],"Ensembl":"ENSG00000114374","Gene description":"Ubiquitin specific peptidase 9 Y-linked","Uniprot":["O00507"],"Chromosome":"Y","Position":"12537650-12860839","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"64.6","Excitatory neurons":"89.5","Inhibitory neurons":"69.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"5.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RPTEC TERT1":"21.5","RT4":"17.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057687"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA057687":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.6","Tissue RNA - adrenal gland [nTPM]":"5.2","Tissue RNA - amygdala [nTPM]":"1.3","Tissue RNA - appendix [nTPM]":"1.7","Tissue RNA - basal ganglia [nTPM]":"1.4","Tissue RNA - bone marrow [nTPM]":"2.6","Tissue RNA - breast [nTPM]":"3.3","Tissue RNA - cerebellum [nTPM]":"2.8","Tissue RNA - cerebral cortex [nTPM]":"5.2","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"2.5","Tissue RNA - colon [nTPM]":"4.5","Tissue RNA - duodenum [nTPM]":"1.7","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"7.2","Tissue RNA - esophagus [nTPM]":"5.2","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"4.6","Tissue RNA - heart muscle [nTPM]":"5.5","Tissue RNA - hippocampal formation [nTPM]":"1.3","Tissue RNA - hypothalamus [nTPM]":"1.4","Tissue RNA - kidney [nTPM]":"7.1","Tissue RNA - liver [nTPM]":"3.0","Tissue RNA - lung [nTPM]":"5.2","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"1.2","Tissue RNA - midbrain [nTPM]":"1.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"6.0","Tissue RNA - parathyroid gland [nTPM]":"3.5","Tissue RNA - pituitary gland [nTPM]":"8.8","Tissue RNA - placenta [nTPM]":"2.3","Tissue RNA - pons [nTPM]":"1.3","Tissue RNA - prostate [nTPM]":"9.7","Tissue RNA - rectum [nTPM]":"4.9","Tissue RNA - retina [nTPM]":"12.9","Tissue RNA - salivary gland [nTPM]":"4.9","Tissue RNA - seminal vesicle [nTPM]":"7.0","Tissue RNA - skeletal muscle [nTPM]":"5.2","Tissue RNA - skin 1 [nTPM]":"3.2","Tissue RNA - small intestine [nTPM]":"4.4","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"5.1","Tissue RNA - stomach 1 [nTPM]":"3.9","Tissue RNA - testis [nTPM]":"4.2","Tissue RNA - thalamus [nTPM]":"1.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"5.7","Tissue RNA - tongue [nTPM]":"9.7","Tissue RNA - tonsil [nTPM]":"5.6","Tissue RNA - urinary bladder [nTPM]":"4.5","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"2.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"4.7","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"5.3","Cell RNA - BJ [nTPM]":"14.2","Cell RNA - BJ hTERT+ [nTPM]":"14.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.5","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"7.7","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"12.2","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"8.6","Cell RNA - HDLM-2 [nTPM]":"8.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"7.3","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"9.5","Cell RNA - HHSteC [nTPM]":"5.8","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"9.7","Cell RNA - hTCEpi [nTPM]":"8.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"3.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"12.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"9.8","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"4.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"3.5","Cell RNA - RPMI-8226 [nTPM]":"2.1","Cell RNA - RPTEC TERT1 [nTPM]":"21.5","Cell RNA - RT4 [nTPM]":"17.4","Cell RNA - SCLC-21H [nTPM]":"7.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"4.4","Cell RNA - SuSa [nTPM]":"12.5","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"10.6","Cell RNA - U-138 MG [nTPM]":"9.5","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"7.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"9.7","Cell RNA - U-698 [nTPM]":"15.1","Cell RNA - U-87 MG [nTPM]":"0.5","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.9","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.7","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.3","Brain RNA - basal ganglia [nTPM]":"1.4","Brain RNA - cerebellum [nTPM]":"2.8","Brain RNA - cerebral cortex [nTPM]":"5.2","Brain RNA - hippocampal formation [nTPM]":"1.3","Brain RNA - hypothalamus [nTPM]":"1.4","Brain RNA - medulla oblongata [nTPM]":"1.2","Brain RNA - midbrain [nTPM]":"1.1","Brain RNA - pons [nTPM]":"1.3","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"1.4","Brain RNA - white matter [nTPM]":"2.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.5","Single Cell Type RNA - Astrocytes [nTPM]":"29.4","Single Cell Type RNA - B-cells [nTPM]":"11.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.2","Single Cell Type RNA - Bipolar cells [nTPM]":"23.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"26.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"12.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"64.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.3","Single Cell Type RNA - dendritic cells [nTPM]":"5.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"5.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"89.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.7","Single Cell Type RNA - Fibroblasts [nTPM]":"8.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"2.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.1","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"69.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.1","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.6","Single Cell Type RNA - Langerhans cells [nTPM]":"9.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.1","Single Cell Type RNA - Leydig cells [nTPM]":"12.5","Single Cell Type RNA - Macrophages [nTPM]":"3.6","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"31.9","Single Cell Type RNA - monocytes [nTPM]":"3.6","Single Cell Type RNA - Muller glia cells [nTPM]":"8.8","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"28.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"15.4","Single Cell Type RNA - Plasma cells [nTPM]":"4.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.4","Single Cell Type RNA - Spermatocytes [nTPM]":"2.8","Single Cell Type RNA - Spermatogonia [nTPM]":"2.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - T-cells [nTPM]":"14.7","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.5","Single Cell Type RNA - Urothelial cells [nTPM]":"11.9"},{"Gene":"VANGL1","Gene synonym":["STB2"],"Ensembl":"ENSG00000173218","Gene description":"VANGL planar cell polarity protein 1","Uniprot":["Q8TAA9"],"Chromosome":"1","Position":"115641970-115698224","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"39.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"6.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"dendritic cells":"2.3","NK-cells":"6.2","T-cells":"3.0"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA025235","CAB076375"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB076375":"AB_2665604","HPA025235":"AB_1858718"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.53e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.43e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.89e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.71e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.06e-3"},"Tissue RNA - adipose tissue [nTPM]":"4.9","Tissue RNA - adrenal gland [nTPM]":"3.9","Tissue RNA - amygdala [nTPM]":"2.1","Tissue RNA - appendix [nTPM]":"3.8","Tissue RNA - basal ganglia [nTPM]":"1.2","Tissue RNA - bone marrow [nTPM]":"2.5","Tissue RNA - breast [nTPM]":"3.2","Tissue RNA - cerebellum [nTPM]":"0.8","Tissue RNA - cerebral cortex [nTPM]":"1.1","Tissue RNA - cervix [nTPM]":"9.1","Tissue RNA - choroid plexus [nTPM]":"3.0","Tissue RNA - colon [nTPM]":"6.8","Tissue RNA - duodenum [nTPM]":"3.8","Tissue RNA - endometrium 1 [nTPM]":"5.5","Tissue RNA - epididymis [nTPM]":"4.9","Tissue RNA - esophagus [nTPM]":"10.4","Tissue RNA - fallopian tube [nTPM]":"12.0","Tissue RNA - gallbladder [nTPM]":"3.8","Tissue RNA - heart muscle [nTPM]":"5.4","Tissue RNA - hippocampal formation [nTPM]":"1.3","Tissue RNA - hypothalamus [nTPM]":"1.3","Tissue RNA - kidney [nTPM]":"5.3","Tissue RNA - liver [nTPM]":"3.0","Tissue RNA - lung [nTPM]":"4.1","Tissue RNA - lymph node [nTPM]":"2.1","Tissue RNA - medulla oblongata [nTPM]":"1.2","Tissue RNA - midbrain [nTPM]":"3.0","Tissue RNA - ovary [nTPM]":"4.4","Tissue RNA - pancreas [nTPM]":"5.0","Tissue RNA - parathyroid gland [nTPM]":"5.2","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"3.6","Tissue RNA - pons [nTPM]":"1.7","Tissue RNA - prostate [nTPM]":"4.4","Tissue RNA - rectum [nTPM]":"6.4","Tissue RNA - retina [nTPM]":"1.6","Tissue RNA - salivary gland [nTPM]":"6.4","Tissue RNA - seminal vesicle [nTPM]":"4.5","Tissue RNA - skeletal muscle [nTPM]":"0.9","Tissue RNA - skin 1 [nTPM]":"6.8","Tissue RNA - small intestine [nTPM]":"3.9","Tissue RNA - smooth muscle [nTPM]":"7.3","Tissue RNA - spinal cord [nTPM]":"1.2","Tissue RNA - spleen [nTPM]":"2.2","Tissue RNA - stomach 1 [nTPM]":"5.5","Tissue RNA - testis [nTPM]":"5.0","Tissue RNA - thalamus [nTPM]":"6.5","Tissue RNA - thymus [nTPM]":"7.3","Tissue RNA - thyroid gland [nTPM]":"7.6","Tissue RNA - tongue [nTPM]":"2.4","Tissue RNA - tonsil [nTPM]":"2.5","Tissue RNA - urinary bladder [nTPM]":"6.4","Tissue RNA - vagina [nTPM]":"4.4","Tissue RNA - white matter [nTPM]":"1.0","Cell RNA - A-431 [nTPM]":"49.6","Cell RNA - A549 [nTPM]":"20.7","Cell RNA - AF22 [nTPM]":"6.6","Cell RNA - AN3-CA [nTPM]":"8.9","Cell RNA - ASC diff [nTPM]":"24.1","Cell RNA - ASC TERT1 [nTPM]":"21.5","Cell RNA - BEWO [nTPM]":"13.1","Cell RNA - BJ [nTPM]":"18.8","Cell RNA - BJ hTERT+ [nTPM]":"13.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.1","Cell RNA - CACO-2 [nTPM]":"12.0","Cell RNA - CAPAN-2 [nTPM]":"24.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"31.5","Cell RNA - fHDF\/TERT166 [nTPM]":"21.9","Cell RNA - GAMG [nTPM]":"22.7","Cell RNA - HaCaT [nTPM]":"60.9","Cell RNA - HAP1 [nTPM]":"11.2","Cell RNA - HBEC3-KT [nTPM]":"33.3","Cell RNA - HBF TERT88 [nTPM]":"15.8","Cell RNA - HDLM-2 [nTPM]":"57.9","Cell RNA - HEK 293 [nTPM]":"13.7","Cell RNA - HEL [nTPM]":"27.4","Cell RNA - HeLa [nTPM]":"18.4","Cell RNA - Hep G2 [nTPM]":"9.8","Cell RNA - HHSteC [nTPM]":"8.8","Cell RNA - HL-60 [nTPM]":"8.2","Cell RNA - HMC-1 [nTPM]":"11.4","Cell RNA - HSkMC [nTPM]":"11.4","Cell RNA - hTCEpi [nTPM]":"23.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"17.2","Cell RNA - hTERT-HME1 [nTPM]":"18.2","Cell RNA - hTERT-RPE1 [nTPM]":"12.8","Cell RNA - HUVEC TERT2 [nTPM]":"24.1","Cell RNA - JURKAT [nTPM]":"45.9","Cell RNA - K-562 [nTPM]":"16.8","Cell RNA - Karpas-707 [nTPM]":"14.8","Cell RNA - LHCN-M2 [nTPM]":"24.5","Cell RNA - MCF7 [nTPM]":"65.7","Cell RNA - MOLT-4 [nTPM]":"41.0","Cell RNA - NB-4 [nTPM]":"3.4","Cell RNA - NTERA-2 [nTPM]":"16.7","Cell RNA - OE19 [nTPM]":"28.8","Cell RNA - PC-3 [nTPM]":"19.5","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"19.1","Cell RNA - RPMI-8226 [nTPM]":"14.3","Cell RNA - RPTEC TERT1 [nTPM]":"11.0","Cell RNA - RT4 [nTPM]":"32.8","Cell RNA - SCLC-21H [nTPM]":"5.9","Cell RNA - SH-SY5Y [nTPM]":"8.0","Cell RNA - SiHa [nTPM]":"33.9","Cell RNA - SK-BR-3 [nTPM]":"22.2","Cell RNA - SK-MEL-30 [nTPM]":"15.4","Cell RNA - SuSa [nTPM]":"12.4","Cell RNA - T-47d [nTPM]":"11.3","Cell RNA - THP-1 [nTPM]":"8.8","Cell RNA - TIME [nTPM]":"26.2","Cell RNA - U-138 MG [nTPM]":"16.5","Cell RNA - U-2 OS [nTPM]":"25.7","Cell RNA - U-2197 [nTPM]":"36.3","Cell RNA - U-251 MG [nTPM]":"34.6","Cell RNA - U-266\/70 [nTPM]":"2.1","Cell RNA - U-266\/84 [nTPM]":"2.3","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"22.3","Cell RNA - U-937 [nTPM]":"14.3","Cell RNA - WM-115 [nTPM]":"41.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.9","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.2","Blood RNA - memory CD8 T-cell [nTPM]":"1.9","Blood RNA - myeloid DC [nTPM]":"2.3","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"2.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"6.2","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"2.0","Blood RNA - T-reg [nTPM]":"3.0","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"2.1","Brain RNA - basal ganglia [nTPM]":"1.2","Brain RNA - cerebellum [nTPM]":"0.8","Brain RNA - cerebral cortex [nTPM]":"1.1","Brain RNA - hippocampal formation [nTPM]":"1.3","Brain RNA - hypothalamus [nTPM]":"1.3","Brain RNA - medulla oblongata [nTPM]":"1.2","Brain RNA - midbrain [nTPM]":"3.0","Brain RNA - pons [nTPM]":"1.7","Brain RNA - spinal cord [nTPM]":"1.2","Brain RNA - thalamus [nTPM]":"6.5","Brain RNA - white matter [nTPM]":"1.0","Single Cell Type RNA - Adipocytes [nTPM]":"9.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.2","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"5.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"9.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.0","Single Cell Type RNA - dendritic cells [nTPM]":"3.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"15.7","Single Cell Type RNA - Early spermatids [nTPM]":"6.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.7","Single Cell Type RNA - Endothelial cells [nTPM]":"10.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"13.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.3","Single Cell Type RNA - Fibroblasts [nTPM]":"10.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"5.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.9","Single Cell Type RNA - Hepatocytes [nTPM]":"2.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.6","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"1.4","Single Cell Type RNA - Late spermatids [nTPM]":"3.0","Single Cell Type RNA - Leydig cells [nTPM]":"5.9","Single Cell Type RNA - Macrophages [nTPM]":"2.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"11.1","Single Cell Type RNA - Muller glia cells [nTPM]":"4.7","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.8","Single Cell Type RNA - Paneth cells [nTPM]":"6.1","Single Cell Type RNA - Peritubular cells [nTPM]":"8.2","Single Cell Type RNA - Plasma cells [nTPM]":"1.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.5","Single Cell Type RNA - Spermatocytes [nTPM]":"5.5","Single Cell Type RNA - Spermatogonia [nTPM]":"7.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"3.1","Single Cell Type RNA - Theca cells [nTPM]":"3.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.3","Single Cell Type RNA - Urothelial cells [nTPM]":"6.5"},{"Gene":"VAPB","Gene synonym":["ALS8","VAP-B","VAP-C"],"Ensembl":"ENSG00000124164","Gene description":"VAMP associated protein B and C","Uniprot":["O95292"],"Chromosome":"20","Position":"58389229-58451101","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction","Unfolded protein response"],"Molecular function":null,"Disease involvement":["Amyotrophic lateral sclerosis","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013144","CAB013722"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"240000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB013722":null,"HPA013144":"AB_1858717"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.08e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.7","Tissue RNA - adrenal gland [nTPM]":"36.4","Tissue RNA - amygdala [nTPM]":"32.1","Tissue RNA - appendix [nTPM]":"11.2","Tissue RNA - basal ganglia [nTPM]":"30.4","Tissue RNA - bone marrow [nTPM]":"4.2","Tissue RNA - breast [nTPM]":"14.2","Tissue RNA - cerebellum [nTPM]":"29.6","Tissue RNA - cerebral cortex [nTPM]":"30.1","Tissue RNA - cervix [nTPM]":"13.7","Tissue RNA - choroid plexus [nTPM]":"20.3","Tissue RNA - colon [nTPM]":"24.2","Tissue RNA - duodenum [nTPM]":"19.6","Tissue RNA - endometrium 1 [nTPM]":"16.4","Tissue RNA - epididymis [nTPM]":"10.3","Tissue RNA - esophagus [nTPM]":"19.3","Tissue RNA - fallopian tube [nTPM]":"14.9","Tissue RNA - gallbladder [nTPM]":"9.7","Tissue RNA - heart muscle [nTPM]":"29.4","Tissue RNA - hippocampal formation [nTPM]":"28.8","Tissue RNA - hypothalamus [nTPM]":"33.5","Tissue RNA - kidney [nTPM]":"24.8","Tissue RNA - liver [nTPM]":"35.0","Tissue RNA - lung [nTPM]":"14.1","Tissue RNA - lymph node [nTPM]":"9.6","Tissue RNA - medulla oblongata [nTPM]":"34.6","Tissue RNA - midbrain [nTPM]":"34.0","Tissue RNA - ovary [nTPM]":"17.9","Tissue RNA - pancreas [nTPM]":"18.9","Tissue RNA - parathyroid gland [nTPM]":"27.9","Tissue RNA - pituitary gland [nTPM]":"21.0","Tissue RNA - placenta [nTPM]":"9.2","Tissue RNA - pons [nTPM]":"36.2","Tissue RNA - prostate [nTPM]":"17.8","Tissue RNA - rectum [nTPM]":"9.9","Tissue RNA - retina [nTPM]":"14.3","Tissue RNA - salivary gland [nTPM]":"16.2","Tissue RNA - seminal vesicle [nTPM]":"12.3","Tissue RNA - skeletal muscle [nTPM]":"46.4","Tissue RNA - skin 1 [nTPM]":"13.0","Tissue RNA - small intestine [nTPM]":"18.2","Tissue RNA - smooth muscle [nTPM]":"11.6","Tissue RNA - spinal cord [nTPM]":"36.4","Tissue RNA - spleen [nTPM]":"15.0","Tissue RNA - stomach 1 [nTPM]":"19.0","Tissue RNA - testis [nTPM]":"8.8","Tissue RNA - thalamus [nTPM]":"37.0","Tissue RNA - thymus [nTPM]":"12.2","Tissue RNA - thyroid gland [nTPM]":"23.3","Tissue RNA - tongue [nTPM]":"39.6","Tissue RNA - tonsil [nTPM]":"6.7","Tissue RNA - urinary bladder [nTPM]":"18.1","Tissue RNA - vagina [nTPM]":"12.9","Tissue RNA - white matter [nTPM]":"31.5","Cell RNA - A-431 [nTPM]":"31.0","Cell RNA - A549 [nTPM]":"30.4","Cell RNA - AF22 [nTPM]":"33.6","Cell RNA - AN3-CA [nTPM]":"18.0","Cell RNA - ASC diff [nTPM]":"30.3","Cell RNA - ASC TERT1 [nTPM]":"12.5","Cell RNA - BEWO [nTPM]":"29.5","Cell RNA - BJ [nTPM]":"27.0","Cell RNA - BJ hTERT+ [nTPM]":"11.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"41.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.1","Cell RNA - CACO-2 [nTPM]":"123.0","Cell RNA - CAPAN-2 [nTPM]":"29.0","Cell RNA - Daudi [nTPM]":"27.2","Cell RNA - EFO-21 [nTPM]":"37.7","Cell RNA - fHDF\/TERT166 [nTPM]":"18.3","Cell RNA - GAMG [nTPM]":"32.3","Cell RNA - HaCaT [nTPM]":"57.6","Cell RNA - HAP1 [nTPM]":"27.1","Cell RNA - HBEC3-KT [nTPM]":"38.9","Cell RNA - HBF TERT88 [nTPM]":"24.6","Cell RNA - HDLM-2 [nTPM]":"12.8","Cell RNA - HEK 293 [nTPM]":"20.2","Cell RNA - HEL [nTPM]":"16.5","Cell RNA - HeLa [nTPM]":"32.2","Cell RNA - Hep G2 [nTPM]":"38.9","Cell RNA - HHSteC [nTPM]":"30.2","Cell RNA - HL-60 [nTPM]":"15.5","Cell RNA - HMC-1 [nTPM]":"19.8","Cell RNA - HSkMC [nTPM]":"28.9","Cell RNA - hTCEpi [nTPM]":"44.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.8","Cell RNA - hTERT-HME1 [nTPM]":"18.7","Cell RNA - hTERT-RPE1 [nTPM]":"19.8","Cell RNA - HUVEC TERT2 [nTPM]":"20.5","Cell RNA - JURKAT [nTPM]":"26.7","Cell RNA - K-562 [nTPM]":"39.5","Cell RNA - Karpas-707 [nTPM]":"14.9","Cell RNA - LHCN-M2 [nTPM]":"20.0","Cell RNA - MCF7 [nTPM]":"96.7","Cell RNA - MOLT-4 [nTPM]":"24.5","Cell RNA - NB-4 [nTPM]":"30.6","Cell RNA - NTERA-2 [nTPM]":"17.7","Cell RNA - OE19 [nTPM]":"60.2","Cell RNA - PC-3 [nTPM]":"40.0","Cell RNA - REH [nTPM]":"24.2","Cell RNA - RH-30 [nTPM]":"31.3","Cell RNA - RPMI-8226 [nTPM]":"18.0","Cell RNA - RPTEC TERT1 [nTPM]":"31.6","Cell RNA - RT4 [nTPM]":"40.7","Cell RNA - SCLC-21H [nTPM]":"47.1","Cell RNA - SH-SY5Y [nTPM]":"32.6","Cell RNA - SiHa [nTPM]":"44.7","Cell RNA - SK-BR-3 [nTPM]":"117.0","Cell RNA - SK-MEL-30 [nTPM]":"48.0","Cell RNA - SuSa [nTPM]":"18.4","Cell RNA - T-47d [nTPM]":"48.0","Cell RNA - THP-1 [nTPM]":"23.2","Cell RNA - TIME [nTPM]":"28.6","Cell RNA - U-138 MG [nTPM]":"65.8","Cell RNA - U-2 OS [nTPM]":"31.9","Cell RNA - U-2197 [nTPM]":"33.3","Cell RNA - U-251 MG [nTPM]":"36.9","Cell RNA - U-266\/70 [nTPM]":"19.9","Cell RNA - U-266\/84 [nTPM]":"23.1","Cell RNA - U-698 [nTPM]":"31.4","Cell RNA - U-87 MG [nTPM]":"55.7","Cell RNA - U-937 [nTPM]":"16.8","Cell RNA - WM-115 [nTPM]":"33.8","Blood RNA - basophil [nTPM]":"2.1","Blood RNA - classical monocyte [nTPM]":"2.3","Blood RNA - eosinophil [nTPM]":"3.1","Blood RNA - gdT-cell [nTPM]":"3.9","Blood RNA - intermediate monocyte [nTPM]":"2.4","Blood RNA - MAIT T-cell [nTPM]":"4.5","Blood RNA - memory B-cell [nTPM]":"2.8","Blood RNA - memory CD4 T-cell [nTPM]":"4.6","Blood RNA - memory CD8 T-cell [nTPM]":"3.2","Blood RNA - myeloid DC [nTPM]":"2.3","Blood RNA - naive B-cell [nTPM]":"2.3","Blood RNA - naive CD4 T-cell [nTPM]":"3.3","Blood RNA - naive CD8 T-cell [nTPM]":"4.8","Blood RNA - neutrophil [nTPM]":"3.7","Blood RNA - NK-cell [nTPM]":"3.7","Blood RNA - non-classical monocyte [nTPM]":"3.0","Blood RNA - plasmacytoid DC [nTPM]":"2.3","Blood RNA - T-reg [nTPM]":"2.7","Blood RNA - total PBMC [nTPM]":"2.6","Brain RNA - amygdala [nTPM]":"32.1","Brain RNA - basal ganglia [nTPM]":"30.4","Brain RNA - cerebellum [nTPM]":"29.6","Brain RNA - cerebral cortex [nTPM]":"30.1","Brain RNA - hippocampal formation [nTPM]":"28.8","Brain RNA - hypothalamus [nTPM]":"33.5","Brain RNA - medulla oblongata [nTPM]":"34.6","Brain RNA - midbrain [nTPM]":"34.0","Brain RNA - pons [nTPM]":"36.2","Brain RNA - spinal cord [nTPM]":"36.4","Brain RNA - thalamus [nTPM]":"37.0","Brain RNA - white matter [nTPM]":"31.5","Single Cell Type RNA - Adipocytes [nTPM]":"22.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.8","Single Cell Type RNA - Astrocytes [nTPM]":"31.6","Single Cell Type RNA - B-cells [nTPM]":"18.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.9","Single Cell Type RNA - Bipolar cells [nTPM]":"29.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"46.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"16.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"34.8","Single Cell Type RNA - dendritic cells [nTPM]":"20.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"28.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"35.1","Single Cell Type RNA - Early spermatids [nTPM]":"5.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.9","Single Cell Type RNA - Endothelial cells [nTPM]":"23.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.7","Single Cell Type RNA - Erythroid cells [nTPM]":"18.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"34.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"50.3","Single Cell Type RNA - Fibroblasts [nTPM]":"24.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.0","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"23.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.7","Single Cell Type RNA - Hepatocytes [nTPM]":"40.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.1","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"34.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.4","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"18.5","Single Cell Type RNA - Langerhans cells [nTPM]":"10.0","Single Cell Type RNA - Late spermatids [nTPM]":"6.1","Single Cell Type RNA - Leydig cells [nTPM]":"18.6","Single Cell Type RNA - Macrophages [nTPM]":"17.3","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"40.3","Single Cell Type RNA - monocytes [nTPM]":"22.8","Single Cell Type RNA - Muller glia cells [nTPM]":"34.3","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"35.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"43.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"37.5","Single Cell Type RNA - Paneth cells [nTPM]":"22.4","Single Cell Type RNA - Peritubular cells [nTPM]":"25.2","Single Cell Type RNA - Plasma cells [nTPM]":"14.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"38.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"42.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"29.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.0","Single Cell Type RNA - Spermatocytes [nTPM]":"22.0","Single Cell Type RNA - Spermatogonia [nTPM]":"29.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"44.5","Single Cell Type RNA - T-cells [nTPM]":"20.5","Single Cell Type RNA - Theca cells [nTPM]":"37.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"27.6","Single Cell Type RNA - Urothelial cells [nTPM]":"16.6"},{"Gene":"VARS1","Gene synonym":["VARS","VARS2"],"Ensembl":"ENSG00000204394","Gene description":"Valyl-tRNA synthetase 1","Uniprot":["P26640"],"Chromosome":"6","Position":"31777518-31795752","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"10.1","Cytotrophoblasts":"23.2","Extravillous trophoblasts":"48.3","Hofbauer cells":"30.7","Syncytiotrophoblasts":"16.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-266\/84":"140.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046710"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA046710":"AB_2679765"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.25e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.86e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.90e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Tissue RNA - adipose tissue [nTPM]":"22.2","Tissue RNA - adrenal gland [nTPM]":"24.6","Tissue RNA - amygdala [nTPM]":"2.0","Tissue RNA - appendix [nTPM]":"6.6","Tissue RNA - basal ganglia [nTPM]":"1.6","Tissue RNA - bone marrow [nTPM]":"3.2","Tissue RNA - breast [nTPM]":"21.9","Tissue RNA - cerebellum [nTPM]":"0.4","Tissue RNA - cerebral cortex [nTPM]":"2.4","Tissue RNA - cervix [nTPM]":"20.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"21.0","Tissue RNA - duodenum [nTPM]":"5.6","Tissue RNA - endometrium 1 [nTPM]":"29.4","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"32.5","Tissue RNA - fallopian tube [nTPM]":"22.1","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"20.0","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"2.3","Tissue RNA - kidney [nTPM]":"19.2","Tissue RNA - liver [nTPM]":"29.3","Tissue RNA - lung [nTPM]":"19.8","Tissue RNA - lymph node [nTPM]":"3.0","Tissue RNA - medulla oblongata [nTPM]":"2.4","Tissue RNA - midbrain [nTPM]":"1.9","Tissue RNA - ovary [nTPM]":"19.7","Tissue RNA - pancreas [nTPM]":"37.3","Tissue RNA - parathyroid gland [nTPM]":"2.5","Tissue RNA - pituitary gland [nTPM]":"33.6","Tissue RNA - placenta [nTPM]":"2.2","Tissue RNA - pons [nTPM]":"2.2","Tissue RNA - prostate [nTPM]":"17.6","Tissue RNA - rectum [nTPM]":"1.7","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"20.6","Tissue RNA - seminal vesicle [nTPM]":"1.2","Tissue RNA - skeletal muscle [nTPM]":"58.2","Tissue RNA - skin 1 [nTPM]":"34.3","Tissue RNA - small intestine [nTPM]":"21.9","Tissue RNA - smooth muscle [nTPM]":"3.5","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"30.0","Tissue RNA - stomach 1 [nTPM]":"23.3","Tissue RNA - testis [nTPM]":"63.6","Tissue RNA - thalamus [nTPM]":"2.6","Tissue RNA - thymus [nTPM]":"3.0","Tissue RNA - thyroid gland [nTPM]":"18.5","Tissue RNA - tongue [nTPM]":"3.1","Tissue RNA - tonsil [nTPM]":"2.8","Tissue RNA - urinary bladder [nTPM]":"23.5","Tissue RNA - vagina [nTPM]":"20.7","Tissue RNA - white matter [nTPM]":"1.5","Cell RNA - A-431 [nTPM]":"36.2","Cell RNA - A549 [nTPM]":"11.6","Cell RNA - AF22 [nTPM]":"12.4","Cell RNA - AN3-CA [nTPM]":"36.9","Cell RNA - ASC diff [nTPM]":"9.1","Cell RNA - ASC TERT1 [nTPM]":"8.5","Cell RNA - BEWO [nTPM]":"84.0","Cell RNA - BJ [nTPM]":"52.2","Cell RNA - BJ hTERT+ [nTPM]":"10.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"25.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.3","Cell RNA - CACO-2 [nTPM]":"11.5","Cell RNA - CAPAN-2 [nTPM]":"9.9","Cell RNA - Daudi [nTPM]":"58.3","Cell RNA - EFO-21 [nTPM]":"60.2","Cell RNA - fHDF\/TERT166 [nTPM]":"18.4","Cell RNA - GAMG [nTPM]":"18.9","Cell RNA - HaCaT [nTPM]":"22.0","Cell RNA - HAP1 [nTPM]":"33.5","Cell RNA - HBEC3-KT [nTPM]":"32.4","Cell RNA - HBF TERT88 [nTPM]":"8.8","Cell RNA - HDLM-2 [nTPM]":"46.0","Cell RNA - HEK 293 [nTPM]":"74.0","Cell RNA - HEL [nTPM]":"31.7","Cell RNA - HeLa [nTPM]":"18.4","Cell RNA - Hep G2 [nTPM]":"21.3","Cell RNA - HHSteC [nTPM]":"18.3","Cell RNA - HL-60 [nTPM]":"75.7","Cell RNA - HMC-1 [nTPM]":"60.6","Cell RNA - HSkMC [nTPM]":"12.5","Cell RNA - hTCEpi [nTPM]":"8.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.8","Cell RNA - hTERT-HME1 [nTPM]":"16.5","Cell RNA - hTERT-RPE1 [nTPM]":"6.2","Cell RNA - HUVEC TERT2 [nTPM]":"13.5","Cell RNA - JURKAT [nTPM]":"22.9","Cell RNA - K-562 [nTPM]":"92.2","Cell RNA - Karpas-707 [nTPM]":"48.8","Cell RNA - LHCN-M2 [nTPM]":"12.7","Cell RNA - MCF7 [nTPM]":"13.2","Cell RNA - MOLT-4 [nTPM]":"51.0","Cell RNA - NB-4 [nTPM]":"16.2","Cell RNA - NTERA-2 [nTPM]":"35.0","Cell RNA - OE19 [nTPM]":"11.9","Cell RNA - PC-3 [nTPM]":"32.5","Cell RNA - REH [nTPM]":"55.5","Cell RNA - RH-30 [nTPM]":"20.5","Cell RNA - RPMI-8226 [nTPM]":"132.7","Cell RNA - RPTEC TERT1 [nTPM]":"13.0","Cell RNA - RT4 [nTPM]":"12.4","Cell RNA - SCLC-21H [nTPM]":"42.1","Cell RNA - SH-SY5Y [nTPM]":"26.2","Cell RNA - SiHa [nTPM]":"12.0","Cell RNA - SK-BR-3 [nTPM]":"31.0","Cell RNA - SK-MEL-30 [nTPM]":"19.5","Cell RNA - SuSa [nTPM]":"5.8","Cell RNA - T-47d [nTPM]":"23.2","Cell RNA - THP-1 [nTPM]":"34.0","Cell RNA - TIME [nTPM]":"31.2","Cell RNA - U-138 MG [nTPM]":"24.2","Cell RNA - U-2 OS [nTPM]":"37.8","Cell RNA - U-2197 [nTPM]":"28.2","Cell RNA - U-251 MG [nTPM]":"72.5","Cell RNA - U-266\/70 [nTPM]":"87.9","Cell RNA - U-266\/84 [nTPM]":"140.4","Cell RNA - U-698 [nTPM]":"44.1","Cell RNA - U-87 MG [nTPM]":"14.6","Cell RNA - U-937 [nTPM]":"31.1","Cell RNA - WM-115 [nTPM]":"29.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"2.0","Brain RNA - basal ganglia [nTPM]":"1.6","Brain RNA - cerebellum [nTPM]":"0.4","Brain RNA - cerebral cortex [nTPM]":"2.4","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"2.3","Brain RNA - medulla oblongata [nTPM]":"2.4","Brain RNA - midbrain [nTPM]":"1.9","Brain RNA - pons [nTPM]":"2.2","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"2.6","Brain RNA - white matter [nTPM]":"1.5","Single Cell Type RNA - Adipocytes [nTPM]":"4.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.2","Single Cell Type RNA - dendritic cells [nTPM]":"1.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"48.3","Single Cell Type RNA - Fibroblasts [nTPM]":"3.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.6","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"VARS2","Gene synonym":["DKFZP434L1435","G7a","KIAA1885","VARS2L","VARSL"],"Ensembl":"ENSG00000137411","Gene description":"Valyl-tRNA synthetase 2, mitochondrial","Uniprot":["Q5ST30"],"Chromosome":"6","Position":"30914205-30926459","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062449","HPA070267"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 23: AN3-CA - Transcription regulation","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA062449":"AB_2684766","HPA070267":"AB_2686245"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.2","Tissue RNA - adrenal gland [nTPM]":"14.4","Tissue RNA - amygdala [nTPM]":"1.3","Tissue RNA - appendix [nTPM]":"2.1","Tissue RNA - basal ganglia [nTPM]":"1.5","Tissue RNA - bone marrow [nTPM]":"1.9","Tissue RNA - breast [nTPM]":"9.7","Tissue RNA - cerebellum [nTPM]":"1.5","Tissue RNA - cerebral cortex [nTPM]":"1.6","Tissue RNA - cervix [nTPM]":"12.5","Tissue RNA - choroid plexus [nTPM]":"0.4","Tissue RNA - colon [nTPM]":"10.5","Tissue RNA - duodenum [nTPM]":"1.2","Tissue RNA - endometrium 1 [nTPM]":"10.4","Tissue RNA - epididymis [nTPM]":"1.5","Tissue RNA - esophagus [nTPM]":"22.5","Tissue RNA - fallopian tube [nTPM]":"10.1","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"11.1","Tissue RNA - hippocampal formation [nTPM]":"1.4","Tissue RNA - hypothalamus [nTPM]":"1.3","Tissue RNA - kidney [nTPM]":"12.5","Tissue RNA - liver [nTPM]":"18.9","Tissue RNA - lung [nTPM]":"10.5","Tissue RNA - lymph node [nTPM]":"3.1","Tissue RNA - medulla oblongata [nTPM]":"1.3","Tissue RNA - midbrain [nTPM]":"1.6","Tissue RNA - ovary [nTPM]":"15.3","Tissue RNA - pancreas [nTPM]":"14.0","Tissue RNA - parathyroid gland [nTPM]":"2.3","Tissue RNA - pituitary gland [nTPM]":"17.1","Tissue RNA - placenta [nTPM]":"0.9","Tissue RNA - pons [nTPM]":"1.4","Tissue RNA - prostate [nTPM]":"10.2","Tissue RNA - rectum [nTPM]":"2.2","Tissue RNA - retina [nTPM]":"1.4","Tissue RNA - salivary gland [nTPM]":"10.9","Tissue RNA - seminal vesicle [nTPM]":"1.1","Tissue RNA - skeletal muscle [nTPM]":"20.9","Tissue RNA - skin 1 [nTPM]":"10.1","Tissue RNA - small intestine [nTPM]":"12.8","Tissue RNA - smooth muscle [nTPM]":"0.7","Tissue RNA - spinal cord [nTPM]":"1.2","Tissue RNA - spleen [nTPM]":"13.4","Tissue RNA - stomach 1 [nTPM]":"11.7","Tissue RNA - testis [nTPM]":"11.8","Tissue RNA - thalamus [nTPM]":"1.3","Tissue RNA - thymus [nTPM]":"4.1","Tissue RNA - thyroid gland [nTPM]":"15.0","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"2.3","Tissue RNA - urinary bladder [nTPM]":"10.5","Tissue RNA - vagina [nTPM]":"13.2","Tissue RNA - white matter [nTPM]":"1.3","Cell RNA - A-431 [nTPM]":"13.8","Cell RNA - A549 [nTPM]":"9.6","Cell RNA - AF22 [nTPM]":"5.5","Cell RNA - AN3-CA [nTPM]":"23.1","Cell RNA - ASC diff [nTPM]":"4.9","Cell RNA - ASC TERT1 [nTPM]":"4.4","Cell RNA - BEWO [nTPM]":"0.7","Cell RNA - BJ [nTPM]":"2.2","Cell RNA - BJ hTERT+ [nTPM]":"1.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.6","Cell RNA - CACO-2 [nTPM]":"12.6","Cell RNA - CAPAN-2 [nTPM]":"8.9","Cell RNA - Daudi [nTPM]":"11.9","Cell RNA - EFO-21 [nTPM]":"7.5","Cell RNA - fHDF\/TERT166 [nTPM]":"3.0","Cell RNA - GAMG [nTPM]":"9.4","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"21.3","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"2.4","Cell RNA - HDLM-2 [nTPM]":"4.6","Cell RNA - HEK 293 [nTPM]":"15.7","Cell RNA - HEL [nTPM]":"13.2","Cell RNA - HeLa [nTPM]":"10.2","Cell RNA - Hep G2 [nTPM]":"0.9","Cell RNA - HHSteC [nTPM]":"6.7","Cell RNA - HL-60 [nTPM]":"2.3","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"6.2","Cell RNA - hTCEpi [nTPM]":"8.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.9","Cell RNA - hTERT-HME1 [nTPM]":"1.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.9","Cell RNA - HUVEC TERT2 [nTPM]":"1.3","Cell RNA - JURKAT [nTPM]":"19.5","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"10.5","Cell RNA - LHCN-M2 [nTPM]":"5.4","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"4.6","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.7","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"1.2","Cell RNA - REH [nTPM]":"9.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"10.3","Cell RNA - RPTEC TERT1 [nTPM]":"18.3","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"8.5","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"6.6","Cell RNA - SK-MEL-30 [nTPM]":"5.4","Cell RNA - SuSa [nTPM]":"5.0","Cell RNA - T-47d [nTPM]":"16.3","Cell RNA - THP-1 [nTPM]":"7.4","Cell RNA - TIME [nTPM]":"2.2","Cell RNA - U-138 MG [nTPM]":"14.2","Cell RNA - U-2 OS [nTPM]":"1.4","Cell RNA - U-2197 [nTPM]":"1.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"10.0","Cell RNA - U-266\/84 [nTPM]":"17.1","Cell RNA - U-698 [nTPM]":"18.8","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.6","Cell RNA - WM-115 [nTPM]":"8.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"1.3","Brain RNA - basal ganglia [nTPM]":"1.5","Brain RNA - cerebellum [nTPM]":"1.5","Brain RNA - cerebral cortex [nTPM]":"1.6","Brain RNA - hippocampal formation [nTPM]":"1.4","Brain RNA - hypothalamus [nTPM]":"1.3","Brain RNA - medulla oblongata [nTPM]":"1.3","Brain RNA - midbrain [nTPM]":"1.6","Brain RNA - pons [nTPM]":"1.4","Brain RNA - spinal cord [nTPM]":"1.2","Brain RNA - thalamus [nTPM]":"1.3","Brain RNA - white matter [nTPM]":"1.3","Single Cell Type RNA - Adipocytes [nTPM]":"3.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.5","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"8.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"6.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"5.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.7","Single Cell Type RNA - dendritic cells [nTPM]":"4.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.7","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.2","Single Cell Type RNA - Endothelial cells [nTPM]":"3.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"3.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.6","Single Cell Type RNA - Fibroblasts [nTPM]":"4.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.6","Single Cell Type RNA - granulocytes [nTPM]":"12.7","Single Cell Type RNA - Granulosa cells [nTPM]":"12.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"22.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.2","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.4","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"6.9","Single Cell Type RNA - Langerhans cells [nTPM]":"3.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"4.1","Single Cell Type RNA - Macrophages [nTPM]":"5.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"7.9","Single Cell Type RNA - Muller glia cells [nTPM]":"2.8","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.9","Single Cell Type RNA - Paneth cells [nTPM]":"4.7","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"12.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.7","Single Cell Type RNA - Spermatocytes [nTPM]":"10.4","Single Cell Type RNA - Spermatogonia [nTPM]":"8.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - T-cells [nTPM]":"4.8","Single Cell Type RNA - Theca cells [nTPM]":"6.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.9","Single Cell Type RNA - Urothelial cells [nTPM]":"3.8"},{"Gene":"VCP","Gene synonym":["CDC48","IBMPFD","p97","TERA"],"Ensembl":"ENSG00000165280","Gene description":"Valosin containing protein","Uniprot":["P55072"],"Chromosome":"9","Position":"35053928-35072668","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Autophagy","DNA damage","DNA repair","Transport","Ubl conjugation pathway"],"Molecular function":["Hydrolase"],"Disease involvement":["Amyotrophic lateral sclerosis","Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"540.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005593","HPA012728","HPA012814"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"34000000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB005593":"AB_2214638","HPA012728":"AB_1858730","HPA012814":"AB_1858729"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.30e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.63e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-2"},"Tissue RNA - adipose tissue [nTPM]":"59.8","Tissue RNA - adrenal gland [nTPM]":"88.4","Tissue RNA - amygdala [nTPM]":"56.8","Tissue RNA - appendix [nTPM]":"33.7","Tissue RNA - basal ganglia [nTPM]":"59.0","Tissue RNA - bone marrow [nTPM]":"52.0","Tissue RNA - breast [nTPM]":"54.2","Tissue RNA - cerebellum [nTPM]":"58.9","Tissue RNA - cerebral cortex [nTPM]":"58.0","Tissue RNA - cervix [nTPM]":"57.8","Tissue RNA - choroid plexus [nTPM]":"72.0","Tissue RNA - colon [nTPM]":"51.8","Tissue RNA - duodenum [nTPM]":"33.8","Tissue RNA - endometrium 1 [nTPM]":"59.0","Tissue RNA - epididymis [nTPM]":"51.6","Tissue RNA - esophagus [nTPM]":"84.9","Tissue RNA - fallopian tube [nTPM]":"49.4","Tissue RNA - gallbladder [nTPM]":"35.3","Tissue RNA - heart muscle [nTPM]":"117.5","Tissue RNA - hippocampal formation [nTPM]":"60.4","Tissue RNA - hypothalamus [nTPM]":"66.2","Tissue RNA - kidney [nTPM]":"59.1","Tissue RNA - liver [nTPM]":"87.5","Tissue RNA - lung [nTPM]":"57.2","Tissue RNA - lymph node [nTPM]":"42.5","Tissue RNA - medulla oblongata [nTPM]":"64.4","Tissue RNA - midbrain [nTPM]":"62.0","Tissue RNA - ovary [nTPM]":"46.1","Tissue RNA - pancreas [nTPM]":"61.2","Tissue RNA - parathyroid gland [nTPM]":"65.7","Tissue RNA - pituitary gland [nTPM]":"57.3","Tissue RNA - placenta [nTPM]":"46.0","Tissue RNA - pons [nTPM]":"68.2","Tissue RNA - prostate [nTPM]":"54.5","Tissue RNA - rectum [nTPM]":"36.5","Tissue RNA - retina [nTPM]":"26.3","Tissue RNA - salivary gland [nTPM]":"63.2","Tissue RNA - seminal vesicle [nTPM]":"58.9","Tissue RNA - skeletal muscle [nTPM]":"176.0","Tissue RNA - skin 1 [nTPM]":"64.0","Tissue RNA - small intestine [nTPM]":"51.8","Tissue RNA - smooth muscle [nTPM]":"42.5","Tissue RNA - spinal cord [nTPM]":"62.3","Tissue RNA - spleen [nTPM]":"64.1","Tissue RNA - stomach 1 [nTPM]":"62.5","Tissue RNA - testis [nTPM]":"45.1","Tissue RNA - thalamus [nTPM]":"63.7","Tissue RNA - thymus [nTPM]":"59.6","Tissue RNA - thyroid gland [nTPM]":"49.7","Tissue RNA - tongue [nTPM]":"135.3","Tissue RNA - tonsil [nTPM]":"53.3","Tissue RNA - urinary bladder [nTPM]":"57.9","Tissue RNA - vagina [nTPM]":"55.3","Tissue RNA - white matter [nTPM]":"69.8","Cell RNA - A-431 [nTPM]":"167.6","Cell RNA - A549 [nTPM]":"223.8","Cell RNA - AF22 [nTPM]":"124.6","Cell RNA - AN3-CA [nTPM]":"57.5","Cell RNA - ASC diff [nTPM]":"187.4","Cell RNA - ASC TERT1 [nTPM]":"135.3","Cell RNA - BEWO [nTPM]":"98.3","Cell RNA - BJ [nTPM]":"153.8","Cell RNA - BJ hTERT+ [nTPM]":"215.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"244.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"197.6","Cell RNA - CACO-2 [nTPM]":"160.0","Cell RNA - CAPAN-2 [nTPM]":"60.1","Cell RNA - Daudi [nTPM]":"140.8","Cell RNA - EFO-21 [nTPM]":"137.2","Cell RNA - fHDF\/TERT166 [nTPM]":"242.9","Cell RNA - GAMG [nTPM]":"173.1","Cell RNA - HaCaT [nTPM]":"69.5","Cell RNA - HAP1 [nTPM]":"253.1","Cell RNA - HBEC3-KT [nTPM]":"230.7","Cell RNA - HBF TERT88 [nTPM]":"227.6","Cell RNA - HDLM-2 [nTPM]":"146.2","Cell RNA - HEK 293 [nTPM]":"126.0","Cell RNA - HEL [nTPM]":"95.3","Cell RNA - HeLa [nTPM]":"216.5","Cell RNA - Hep G2 [nTPM]":"238.0","Cell RNA - HHSteC [nTPM]":"146.5","Cell RNA - HL-60 [nTPM]":"92.4","Cell RNA - HMC-1 [nTPM]":"106.2","Cell RNA - HSkMC [nTPM]":"148.5","Cell RNA - hTCEpi [nTPM]":"136.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"239.2","Cell RNA - hTERT-HME1 [nTPM]":"115.6","Cell RNA - hTERT-RPE1 [nTPM]":"104.4","Cell RNA - HUVEC TERT2 [nTPM]":"276.2","Cell RNA - JURKAT [nTPM]":"56.3","Cell RNA - K-562 [nTPM]":"97.6","Cell RNA - Karpas-707 [nTPM]":"71.4","Cell RNA - LHCN-M2 [nTPM]":"219.2","Cell RNA - MCF7 [nTPM]":"154.7","Cell RNA - MOLT-4 [nTPM]":"114.3","Cell RNA - NB-4 [nTPM]":"234.9","Cell RNA - NTERA-2 [nTPM]":"152.2","Cell RNA - OE19 [nTPM]":"82.7","Cell RNA - PC-3 [nTPM]":"219.1","Cell RNA - REH [nTPM]":"80.7","Cell RNA - RH-30 [nTPM]":"111.8","Cell RNA - RPMI-8226 [nTPM]":"72.8","Cell RNA - RPTEC TERT1 [nTPM]":"204.1","Cell RNA - RT4 [nTPM]":"175.7","Cell RNA - SCLC-21H [nTPM]":"65.7","Cell RNA - SH-SY5Y [nTPM]":"84.1","Cell RNA - SiHa [nTPM]":"100.4","Cell RNA - SK-BR-3 [nTPM]":"81.2","Cell RNA - SK-MEL-30 [nTPM]":"45.1","Cell RNA - SuSa [nTPM]":"152.2","Cell RNA - T-47d [nTPM]":"71.5","Cell RNA - THP-1 [nTPM]":"60.3","Cell RNA - TIME [nTPM]":"215.5","Cell RNA - U-138 MG [nTPM]":"77.5","Cell RNA - U-2 OS [nTPM]":"112.5","Cell RNA - U-2197 [nTPM]":"63.7","Cell RNA - U-251 MG [nTPM]":"118.6","Cell RNA - U-266\/70 [nTPM]":"41.9","Cell RNA - U-266\/84 [nTPM]":"116.5","Cell RNA - U-698 [nTPM]":"104.3","Cell RNA - U-87 MG [nTPM]":"139.5","Cell RNA - U-937 [nTPM]":"67.0","Cell RNA - WM-115 [nTPM]":"105.4","Blood RNA - basophil [nTPM]":"142.0","Blood RNA - classical monocyte [nTPM]":"62.7","Blood RNA - eosinophil [nTPM]":"75.0","Blood RNA - gdT-cell [nTPM]":"58.8","Blood RNA - intermediate monocyte [nTPM]":"70.0","Blood RNA - MAIT T-cell [nTPM]":"62.4","Blood RNA - memory B-cell [nTPM]":"59.2","Blood RNA - memory CD4 T-cell [nTPM]":"59.0","Blood RNA - memory CD8 T-cell [nTPM]":"65.6","Blood RNA - myeloid DC [nTPM]":"75.3","Blood RNA - naive B-cell [nTPM]":"53.0","Blood RNA - naive CD4 T-cell [nTPM]":"42.3","Blood RNA - naive CD8 T-cell [nTPM]":"44.4","Blood RNA - neutrophil [nTPM]":"71.1","Blood RNA - NK-cell [nTPM]":"67.1","Blood RNA - non-classical monocyte [nTPM]":"80.4","Blood RNA - plasmacytoid DC [nTPM]":"49.8","Blood RNA - T-reg [nTPM]":"91.2","Blood RNA - total PBMC [nTPM]":"111.8","Brain RNA - amygdala [nTPM]":"56.8","Brain RNA - basal ganglia [nTPM]":"59.0","Brain RNA - cerebellum [nTPM]":"58.9","Brain RNA - cerebral cortex [nTPM]":"58.0","Brain RNA - hippocampal formation [nTPM]":"60.4","Brain RNA - hypothalamus [nTPM]":"66.2","Brain RNA - medulla oblongata [nTPM]":"64.4","Brain RNA - midbrain [nTPM]":"62.0","Brain RNA - pons [nTPM]":"68.2","Brain RNA - spinal cord [nTPM]":"62.3","Brain RNA - thalamus [nTPM]":"63.7","Brain RNA - white matter [nTPM]":"69.8","Single Cell Type RNA - Adipocytes [nTPM]":"86.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"80.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"73.7","Single Cell Type RNA - Astrocytes [nTPM]":"22.9","Single Cell Type RNA - B-cells [nTPM]":"124.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"77.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"120.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"147.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"111.5","Single Cell Type RNA - Bipolar cells [nTPM]":"86.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"66.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"47.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"220.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"47.1","Single Cell Type RNA - Club cells [nTPM]":"115.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"55.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"118.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"276.8","Single Cell Type RNA - dendritic cells [nTPM]":"91.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"111.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"74.3","Single Cell Type RNA - Ductal cells [nTPM]":"188.6","Single Cell Type RNA - Early spermatids [nTPM]":"43.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"97.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"85.6","Single Cell Type RNA - Endothelial cells [nTPM]":"127.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"84.2","Single Cell Type RNA - Erythroid cells [nTPM]":"137.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"27.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"187.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"164.7","Single Cell Type RNA - Fibroblasts [nTPM]":"109.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"133.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"105.8","Single Cell Type RNA - granulocytes [nTPM]":"62.1","Single Cell Type RNA - Granulosa cells [nTPM]":"106.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"111.0","Single Cell Type RNA - Hepatocytes [nTPM]":"126.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"133.1","Single Cell Type RNA - Horizontal cells [nTPM]":"74.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"27.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"108.3","Single Cell Type RNA - Ionocytes [nTPM]":"89.5","Single Cell Type RNA - Kupffer cells [nTPM]":"57.9","Single Cell Type RNA - Langerhans cells [nTPM]":"65.6","Single Cell Type RNA - Late spermatids [nTPM]":"47.0","Single Cell Type RNA - Leydig cells [nTPM]":"83.9","Single Cell Type RNA - Macrophages [nTPM]":"81.5","Single Cell Type RNA - Melanocytes [nTPM]":"76.5","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"159.6","Single Cell Type RNA - Muller glia cells [nTPM]":"88.7","Single Cell Type RNA - NK-cells [nTPM]":"54.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"31.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"247.9","Single Cell Type RNA - Paneth cells [nTPM]":"69.0","Single Cell Type RNA - Peritubular cells [nTPM]":"86.9","Single Cell Type RNA - Plasma cells [nTPM]":"267.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"118.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"77.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"113.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"102.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"90.0","Single Cell Type RNA - Sertoli cells [nTPM]":"138.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"74.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"154.9","Single Cell Type RNA - Spermatocytes [nTPM]":"144.5","Single Cell Type RNA - Spermatogonia [nTPM]":"118.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"126.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"90.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"540.6","Single Cell Type RNA - T-cells [nTPM]":"105.4","Single Cell Type RNA - Theca cells [nTPM]":"129.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"96.4","Single Cell Type RNA - Urothelial cells [nTPM]":"135.6"},{"Gene":"VEGFC","Gene synonym":["VEGF-C","VRP"],"Ensembl":"ENSG00000150630","Gene description":"Vascular endothelial growth factor C","Uniprot":["P49767"],"Chromosome":"4","Position":"176683538-176792922","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Potential drug targets","Predicted secreted proteins","RAS pathway related proteins","Transporters"],"Biological process":["Angiogenesis","Differentiation"],"Molecular function":["Developmental protein","Growth factor","Mitogen"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"39.3","Endothelial cells":"22.0","Leydig cells":"13.7","Microglial cells":"36.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"22.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ":"146.5","HBF TERT88":"114.4","hTEC\/SVTERT24-B":"116.5","LHCN-M2":"129.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"7.0"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":383000,"Blood concentration - Conc. blood MS [pg\/L]":"340000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.84e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.88e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.17e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Tissue RNA - adipose tissue [nTPM]":"25.0","Tissue RNA - adrenal gland [nTPM]":"6.9","Tissue RNA - amygdala [nTPM]":"2.6","Tissue RNA - appendix [nTPM]":"4.2","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"16.7","Tissue RNA - cerebellum [nTPM]":"2.7","Tissue RNA - cerebral cortex [nTPM]":"2.8","Tissue RNA - cervix [nTPM]":"9.7","Tissue RNA - choroid plexus [nTPM]":"2.1","Tissue RNA - colon [nTPM]":"4.7","Tissue RNA - duodenum [nTPM]":"2.4","Tissue RNA - endometrium 1 [nTPM]":"7.3","Tissue RNA - epididymis [nTPM]":"1.8","Tissue RNA - esophagus [nTPM]":"4.0","Tissue RNA - fallopian tube [nTPM]":"8.5","Tissue RNA - gallbladder [nTPM]":"6.8","Tissue RNA - heart muscle [nTPM]":"12.7","Tissue RNA - hippocampal formation [nTPM]":"2.4","Tissue RNA - hypothalamus [nTPM]":"2.4","Tissue RNA - kidney [nTPM]":"6.7","Tissue RNA - liver [nTPM]":"4.2","Tissue RNA - lung [nTPM]":"16.8","Tissue RNA - lymph node [nTPM]":"8.0","Tissue RNA - medulla oblongata [nTPM]":"3.1","Tissue RNA - midbrain [nTPM]":"2.8","Tissue RNA - ovary [nTPM]":"5.9","Tissue RNA - pancreas [nTPM]":"1.8","Tissue RNA - parathyroid gland [nTPM]":"2.7","Tissue RNA - pituitary gland [nTPM]":"1.5","Tissue RNA - placenta [nTPM]":"19.3","Tissue RNA - pons [nTPM]":"2.9","Tissue RNA - prostate [nTPM]":"5.1","Tissue RNA - rectum [nTPM]":"3.3","Tissue RNA - retina [nTPM]":"1.2","Tissue RNA - salivary gland [nTPM]":"7.4","Tissue RNA - seminal vesicle [nTPM]":"5.0","Tissue RNA - skeletal muscle [nTPM]":"3.1","Tissue RNA - skin 1 [nTPM]":"5.1","Tissue RNA - small intestine [nTPM]":"6.8","Tissue RNA - smooth muscle [nTPM]":"6.6","Tissue RNA - spinal cord [nTPM]":"2.6","Tissue RNA - spleen [nTPM]":"3.9","Tissue RNA - stomach 1 [nTPM]":"3.2","Tissue RNA - testis [nTPM]":"1.4","Tissue RNA - thalamus [nTPM]":"3.7","Tissue RNA - thymus [nTPM]":"1.1","Tissue RNA - thyroid gland [nTPM]":"27.7","Tissue RNA - tongue [nTPM]":"4.1","Tissue RNA - tonsil [nTPM]":"3.4","Tissue RNA - urinary bladder [nTPM]":"10.3","Tissue RNA - vagina [nTPM]":"7.6","Tissue RNA - white matter [nTPM]":"2.5","Cell RNA - A-431 [nTPM]":"5.9","Cell RNA - A549 [nTPM]":"2.8","Cell RNA - AF22 [nTPM]":"1.8","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"25.5","Cell RNA - ASC TERT1 [nTPM]":"25.3","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"146.5","Cell RNA - BJ hTERT+ [nTPM]":"87.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"79.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"62.5","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.7","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"82.7","Cell RNA - GAMG [nTPM]":"33.1","Cell RNA - HaCaT [nTPM]":"4.4","Cell RNA - HAP1 [nTPM]":"1.3","Cell RNA - HBEC3-KT [nTPM]":"54.8","Cell RNA - HBF TERT88 [nTPM]":"114.4","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"2.8","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"3.8","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"13.9","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"27.0","Cell RNA - hTCEpi [nTPM]":"2.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"116.5","Cell RNA - hTERT-HME1 [nTPM]":"80.5","Cell RNA - hTERT-RPE1 [nTPM]":"79.3","Cell RNA - HUVEC TERT2 [nTPM]":"49.7","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"129.9","Cell RNA - MCF7 [nTPM]":"2.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"47.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"8.4","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"3.3","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"2.3","Cell RNA - SK-BR-3 [nTPM]":"3.3","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.7","Cell RNA - T-47d [nTPM]":"0.7","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"24.2","Cell RNA - U-138 MG [nTPM]":"83.6","Cell RNA - U-2 OS [nTPM]":"9.2","Cell RNA - U-2197 [nTPM]":"20.8","Cell RNA - U-251 MG [nTPM]":"42.1","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"34.9","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"9.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.6","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"2.7","Brain RNA - cerebral cortex [nTPM]":"2.8","Brain RNA - hippocampal formation [nTPM]":"2.4","Brain RNA - hypothalamus [nTPM]":"2.4","Brain RNA - medulla oblongata [nTPM]":"3.1","Brain RNA - midbrain [nTPM]":"2.8","Brain RNA - pons [nTPM]":"2.9","Brain RNA - spinal cord [nTPM]":"2.6","Brain RNA - thalamus [nTPM]":"3.7","Brain RNA - white matter [nTPM]":"2.5","Single Cell Type RNA - Adipocytes [nTPM]":"39.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"10.1","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.5","Single Cell Type RNA - Early spermatids [nTPM]":"3.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.9","Single Cell Type RNA - Endothelial cells [nTPM]":"22.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"9.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"8.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"2.2","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"13.7","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"36.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"3.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"2.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"1.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"3.6"},{"Gene":"VPS13A","Gene synonym":["CHAC","KIAA0986"],"Ensembl":"ENSG00000197969","Gene description":"Vacuolar protein sorting 13 homolog A","Uniprot":["Q96RL7"],"Chromosome":"9","Position":"77177445-77421537","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"228.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021652","HPA021662"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA021652":"AB_1858759","HPA021662":"AB_1858760"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.1","Tissue RNA - adrenal gland [nTPM]":"7.6","Tissue RNA - amygdala [nTPM]":"2.6","Tissue RNA - appendix [nTPM]":"7.1","Tissue RNA - basal ganglia [nTPM]":"4.8","Tissue RNA - bone marrow [nTPM]":"17.6","Tissue RNA - breast [nTPM]":"7.3","Tissue RNA - cerebellum [nTPM]":"11.2","Tissue RNA - cerebral cortex [nTPM]":"9.6","Tissue RNA - cervix [nTPM]":"4.4","Tissue RNA - choroid plexus [nTPM]":"3.6","Tissue RNA - colon [nTPM]":"9.4","Tissue RNA - duodenum [nTPM]":"16.3","Tissue RNA - endometrium 1 [nTPM]":"6.0","Tissue RNA - epididymis [nTPM]":"8.0","Tissue RNA - esophagus [nTPM]":"7.6","Tissue RNA - fallopian tube [nTPM]":"4.7","Tissue RNA - gallbladder [nTPM]":"9.0","Tissue RNA - heart muscle [nTPM]":"9.5","Tissue RNA - hippocampal formation [nTPM]":"6.0","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"9.9","Tissue RNA - liver [nTPM]":"7.4","Tissue RNA - lung [nTPM]":"6.3","Tissue RNA - lymph node [nTPM]":"8.8","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"3.6","Tissue RNA - pancreas [nTPM]":"8.8","Tissue RNA - parathyroid gland [nTPM]":"9.3","Tissue RNA - pituitary gland [nTPM]":"6.5","Tissue RNA - placenta [nTPM]":"3.6","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"6.7","Tissue RNA - rectum [nTPM]":"11.4","Tissue RNA - retina [nTPM]":"7.2","Tissue RNA - salivary gland [nTPM]":"8.0","Tissue RNA - seminal vesicle [nTPM]":"6.6","Tissue RNA - skeletal muscle [nTPM]":"14.6","Tissue RNA - skin 1 [nTPM]":"15.6","Tissue RNA - small intestine [nTPM]":"13.8","Tissue RNA - smooth muscle [nTPM]":"7.2","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"10.6","Tissue RNA - stomach 1 [nTPM]":"12.3","Tissue RNA - testis [nTPM]":"16.8","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"10.3","Tissue RNA - thyroid gland [nTPM]":"8.5","Tissue RNA - tongue [nTPM]":"9.8","Tissue RNA - tonsil [nTPM]":"7.6","Tissue RNA - urinary bladder [nTPM]":"6.4","Tissue RNA - vagina [nTPM]":"6.2","Tissue RNA - white matter [nTPM]":"3.1","Cell RNA - A-431 [nTPM]":"21.0","Cell RNA - A549 [nTPM]":"10.4","Cell RNA - AF22 [nTPM]":"9.1","Cell RNA - AN3-CA [nTPM]":"7.9","Cell RNA - ASC diff [nTPM]":"8.5","Cell RNA - ASC TERT1 [nTPM]":"7.4","Cell RNA - BEWO [nTPM]":"13.7","Cell RNA - BJ [nTPM]":"11.4","Cell RNA - BJ hTERT+ [nTPM]":"10.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.1","Cell RNA - CACO-2 [nTPM]":"4.2","Cell RNA - CAPAN-2 [nTPM]":"9.3","Cell RNA - Daudi [nTPM]":"16.4","Cell RNA - EFO-21 [nTPM]":"5.2","Cell RNA - fHDF\/TERT166 [nTPM]":"10.6","Cell RNA - GAMG [nTPM]":"11.9","Cell RNA - HaCaT [nTPM]":"27.9","Cell RNA - HAP1 [nTPM]":"13.7","Cell RNA - HBEC3-KT [nTPM]":"11.3","Cell RNA - HBF TERT88 [nTPM]":"17.4","Cell RNA - HDLM-2 [nTPM]":"15.5","Cell RNA - HEK 293 [nTPM]":"11.0","Cell RNA - HEL [nTPM]":"21.7","Cell RNA - HeLa [nTPM]":"21.3","Cell RNA - Hep G2 [nTPM]":"10.3","Cell RNA - HHSteC [nTPM]":"8.3","Cell RNA - HL-60 [nTPM]":"28.3","Cell RNA - HMC-1 [nTPM]":"13.9","Cell RNA - HSkMC [nTPM]":"4.7","Cell RNA - hTCEpi [nTPM]":"16.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.5","Cell RNA - hTERT-HME1 [nTPM]":"17.7","Cell RNA - hTERT-RPE1 [nTPM]":"17.3","Cell RNA - HUVEC TERT2 [nTPM]":"14.1","Cell RNA - JURKAT [nTPM]":"15.7","Cell RNA - K-562 [nTPM]":"14.3","Cell RNA - Karpas-707 [nTPM]":"17.4","Cell RNA - LHCN-M2 [nTPM]":"6.0","Cell RNA - MCF7 [nTPM]":"9.8","Cell RNA - MOLT-4 [nTPM]":"21.7","Cell RNA - NB-4 [nTPM]":"9.7","Cell RNA - NTERA-2 [nTPM]":"10.2","Cell RNA - OE19 [nTPM]":"11.9","Cell RNA - PC-3 [nTPM]":"8.3","Cell RNA - REH [nTPM]":"15.7","Cell RNA - RH-30 [nTPM]":"17.4","Cell RNA - RPMI-8226 [nTPM]":"6.8","Cell RNA - RPTEC TERT1 [nTPM]":"14.1","Cell RNA - RT4 [nTPM]":"20.2","Cell RNA - SCLC-21H [nTPM]":"13.3","Cell RNA - SH-SY5Y [nTPM]":"13.3","Cell RNA - SiHa [nTPM]":"14.3","Cell RNA - SK-BR-3 [nTPM]":"9.2","Cell RNA - SK-MEL-30 [nTPM]":"6.3","Cell RNA - SuSa [nTPM]":"16.6","Cell RNA - T-47d [nTPM]":"6.3","Cell RNA - THP-1 [nTPM]":"6.3","Cell RNA - TIME [nTPM]":"18.6","Cell RNA - U-138 MG [nTPM]":"10.4","Cell RNA - U-2 OS [nTPM]":"11.3","Cell RNA - U-2197 [nTPM]":"14.4","Cell RNA - U-251 MG [nTPM]":"14.6","Cell RNA - U-266\/70 [nTPM]":"9.7","Cell RNA - U-266\/84 [nTPM]":"9.6","Cell RNA - U-698 [nTPM]":"8.4","Cell RNA - U-87 MG [nTPM]":"10.8","Cell RNA - U-937 [nTPM]":"13.2","Cell RNA - WM-115 [nTPM]":"4.2","Blood RNA - basophil [nTPM]":"3.8","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"2.0","Blood RNA - gdT-cell [nTPM]":"1.2","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"1.2","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.8","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"1.2","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"2.2","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"2.6","Brain RNA - basal ganglia [nTPM]":"4.8","Brain RNA - cerebellum [nTPM]":"11.2","Brain RNA - cerebral cortex [nTPM]":"9.6","Brain RNA - hippocampal formation [nTPM]":"6.0","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"3.1","Single Cell Type RNA - Adipocytes [nTPM]":"29.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"64.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"46.5","Single Cell Type RNA - Astrocytes [nTPM]":"48.3","Single Cell Type RNA - B-cells [nTPM]":"32.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"33.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"26.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"28.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"27.3","Single Cell Type RNA - Bipolar cells [nTPM]":"29.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"22.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"87.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"41.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"58.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.2","Single Cell Type RNA - dendritic cells [nTPM]":"42.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"78.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"18.2","Single Cell Type RNA - Early spermatids [nTPM]":"90.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"33.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"28.2","Single Cell Type RNA - Endothelial cells [nTPM]":"38.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"87.8","Single Cell Type RNA - Erythroid cells [nTPM]":"48.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"228.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.8","Single Cell Type RNA - Fibroblasts [nTPM]":"18.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"86.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"42.6","Single Cell Type RNA - granulocytes [nTPM]":"19.0","Single Cell Type RNA - Granulosa cells [nTPM]":"32.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"37.5","Single Cell Type RNA - Hepatocytes [nTPM]":"34.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.6","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"101.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"47.4","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"10.6","Single Cell Type RNA - Langerhans cells [nTPM]":"14.4","Single Cell Type RNA - Late spermatids [nTPM]":"55.0","Single Cell Type RNA - Leydig cells [nTPM]":"13.7","Single Cell Type RNA - Macrophages [nTPM]":"13.3","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"43.1","Single Cell Type RNA - monocytes [nTPM]":"11.9","Single Cell Type RNA - Muller glia cells [nTPM]":"16.4","Single Cell Type RNA - NK-cells [nTPM]":"41.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"72.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"23.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"46.2","Single Cell Type RNA - Paneth cells [nTPM]":"42.9","Single Cell Type RNA - Peritubular cells [nTPM]":"15.8","Single Cell Type RNA - Plasma cells [nTPM]":"42.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"31.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"98.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"21.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"38.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.2","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"33.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"30.5","Single Cell Type RNA - Spermatocytes [nTPM]":"74.3","Single Cell Type RNA - Spermatogonia [nTPM]":"64.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"36.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"31.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.9","Single Cell Type RNA - T-cells [nTPM]":"43.2","Single Cell Type RNA - Theca cells [nTPM]":"38.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"39.8","Single Cell Type RNA - Urothelial cells [nTPM]":"25.7"},{"Gene":"VPS35","Gene synonym":["FLJ10752","MEM3","PARK17"],"Ensembl":"ENSG00000069329","Gene description":"VPS35 retromer complex component","Uniprot":["Q96QK1"],"Chromosome":"16","Position":"46656132-46689518","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Host-virus interaction","Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040802"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endosomes","Lysosomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"500000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Endosomes","Lysosomes"],"Subcellular additional location":null,"Antibody RRID":{"HPA040802":"AB_2677142"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.74e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.10e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.75e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-3"},"Tissue RNA - adipose tissue [nTPM]":"5.4","Tissue RNA - adrenal gland [nTPM]":"4.2","Tissue RNA - amygdala [nTPM]":"2.9","Tissue RNA - appendix [nTPM]":"3.0","Tissue RNA - basal ganglia [nTPM]":"3.0","Tissue RNA - bone marrow [nTPM]":"9.5","Tissue RNA - breast [nTPM]":"4.6","Tissue RNA - cerebellum [nTPM]":"2.6","Tissue RNA - cerebral cortex [nTPM]":"3.2","Tissue RNA - cervix [nTPM]":"4.2","Tissue RNA - choroid plexus [nTPM]":"2.8","Tissue RNA - colon [nTPM]":"4.2","Tissue RNA - duodenum [nTPM]":"1.9","Tissue RNA - endometrium 1 [nTPM]":"4.3","Tissue RNA - epididymis [nTPM]":"1.9","Tissue RNA - esophagus [nTPM]":"4.7","Tissue RNA - fallopian tube [nTPM]":"4.0","Tissue RNA - gallbladder [nTPM]":"1.4","Tissue RNA - heart muscle [nTPM]":"6.1","Tissue RNA - hippocampal formation [nTPM]":"3.0","Tissue RNA - hypothalamus [nTPM]":"2.5","Tissue RNA - kidney [nTPM]":"3.7","Tissue RNA - liver [nTPM]":"1.7","Tissue RNA - lung [nTPM]":"4.1","Tissue RNA - lymph node [nTPM]":"2.9","Tissue RNA - medulla oblongata [nTPM]":"3.0","Tissue RNA - midbrain [nTPM]":"2.4","Tissue RNA - ovary [nTPM]":"4.7","Tissue RNA - pancreas [nTPM]":"4.4","Tissue RNA - parathyroid gland [nTPM]":"5.2","Tissue RNA - pituitary gland [nTPM]":"3.3","Tissue RNA - placenta [nTPM]":"2.1","Tissue RNA - pons [nTPM]":"3.2","Tissue RNA - prostate [nTPM]":"3.0","Tissue RNA - rectum [nTPM]":"1.8","Tissue RNA - retina [nTPM]":"4.1","Tissue RNA - salivary gland [nTPM]":"4.5","Tissue RNA - seminal vesicle [nTPM]":"2.4","Tissue RNA - skeletal muscle [nTPM]":"4.6","Tissue RNA - skin 1 [nTPM]":"6.1","Tissue RNA - small intestine [nTPM]":"4.9","Tissue RNA - smooth muscle [nTPM]":"1.7","Tissue RNA - spinal cord [nTPM]":"2.1","Tissue RNA - spleen [nTPM]":"4.2","Tissue RNA - stomach 1 [nTPM]":"4.5","Tissue RNA - testis [nTPM]":"2.7","Tissue RNA - thalamus [nTPM]":"2.8","Tissue RNA - thymus [nTPM]":"3.9","Tissue RNA - thyroid gland [nTPM]":"2.7","Tissue RNA - tongue [nTPM]":"2.7","Tissue RNA - tonsil [nTPM]":"1.8","Tissue RNA - urinary bladder [nTPM]":"4.5","Tissue RNA - vagina [nTPM]":"4.2","Tissue RNA - white matter [nTPM]":"3.4","Cell RNA - A-431 [nTPM]":"3.2","Cell RNA - A549 [nTPM]":"5.0","Cell RNA - AF22 [nTPM]":"4.1","Cell RNA - AN3-CA [nTPM]":"2.8","Cell RNA - ASC diff [nTPM]":"6.5","Cell RNA - ASC TERT1 [nTPM]":"7.3","Cell RNA - BEWO [nTPM]":"2.1","Cell RNA - BJ [nTPM]":"3.8","Cell RNA - BJ hTERT+ [nTPM]":"5.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.7","Cell RNA - CACO-2 [nTPM]":"4.3","Cell RNA - CAPAN-2 [nTPM]":"2.7","Cell RNA - Daudi [nTPM]":"4.2","Cell RNA - EFO-21 [nTPM]":"2.3","Cell RNA - fHDF\/TERT166 [nTPM]":"6.5","Cell RNA - GAMG [nTPM]":"3.3","Cell RNA - HaCaT [nTPM]":"3.9","Cell RNA - HAP1 [nTPM]":"7.5","Cell RNA - HBEC3-KT [nTPM]":"7.5","Cell RNA - HBF TERT88 [nTPM]":"9.1","Cell RNA - HDLM-2 [nTPM]":"1.6","Cell RNA - HEK 293 [nTPM]":"6.4","Cell RNA - HEL [nTPM]":"3.9","Cell RNA - HeLa [nTPM]":"3.8","Cell RNA - Hep G2 [nTPM]":"3.0","Cell RNA - HHSteC [nTPM]":"5.4","Cell RNA - HL-60 [nTPM]":"5.2","Cell RNA - HMC-1 [nTPM]":"5.8","Cell RNA - HSkMC [nTPM]":"5.8","Cell RNA - hTCEpi [nTPM]":"5.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.3","Cell RNA - hTERT-HME1 [nTPM]":"4.5","Cell RNA - hTERT-RPE1 [nTPM]":"6.3","Cell RNA - HUVEC TERT2 [nTPM]":"6.6","Cell RNA - JURKAT [nTPM]":"6.0","Cell RNA - K-562 [nTPM]":"3.1","Cell RNA - Karpas-707 [nTPM]":"1.8","Cell RNA - LHCN-M2 [nTPM]":"6.5","Cell RNA - MCF7 [nTPM]":"2.9","Cell RNA - MOLT-4 [nTPM]":"4.0","Cell RNA - NB-4 [nTPM]":"5.0","Cell RNA - NTERA-2 [nTPM]":"1.4","Cell RNA - OE19 [nTPM]":"3.0","Cell RNA - PC-3 [nTPM]":"6.6","Cell RNA - REH [nTPM]":"5.4","Cell RNA - RH-30 [nTPM]":"5.4","Cell RNA - RPMI-8226 [nTPM]":"5.2","Cell RNA - RPTEC TERT1 [nTPM]":"5.2","Cell RNA - RT4 [nTPM]":"4.4","Cell RNA - SCLC-21H [nTPM]":"1.8","Cell RNA - SH-SY5Y [nTPM]":"2.1","Cell RNA - SiHa [nTPM]":"4.1","Cell RNA - SK-BR-3 [nTPM]":"3.2","Cell RNA - SK-MEL-30 [nTPM]":"1.8","Cell RNA - SuSa [nTPM]":"4.5","Cell RNA - T-47d [nTPM]":"1.9","Cell RNA - THP-1 [nTPM]":"2.6","Cell RNA - TIME [nTPM]":"3.9","Cell RNA - U-138 MG [nTPM]":"1.9","Cell RNA - U-2 OS [nTPM]":"1.9","Cell RNA - U-2197 [nTPM]":"4.3","Cell RNA - U-251 MG [nTPM]":"2.7","Cell RNA - U-266\/70 [nTPM]":"2.3","Cell RNA - U-266\/84 [nTPM]":"3.2","Cell RNA - U-698 [nTPM]":"4.9","Cell RNA - U-87 MG [nTPM]":"3.4","Cell RNA - U-937 [nTPM]":"4.0","Cell RNA - WM-115 [nTPM]":"1.3","Blood RNA - basophil [nTPM]":"1.8","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"1.3","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"1.7","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.7","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"1.5","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"2.3","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"1.1","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"2.9","Brain RNA - basal ganglia [nTPM]":"3.0","Brain RNA - cerebellum [nTPM]":"2.6","Brain RNA - cerebral cortex [nTPM]":"3.2","Brain RNA - hippocampal formation [nTPM]":"3.0","Brain RNA - hypothalamus [nTPM]":"2.5","Brain RNA - medulla oblongata [nTPM]":"3.0","Brain RNA - midbrain [nTPM]":"2.4","Brain RNA - pons [nTPM]":"3.2","Brain RNA - spinal cord [nTPM]":"2.1","Brain RNA - thalamus [nTPM]":"2.8","Brain RNA - white matter [nTPM]":"3.4","Single Cell Type RNA - Adipocytes [nTPM]":"65.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"59.4","Single Cell Type RNA - Astrocytes [nTPM]":"20.5","Single Cell Type RNA - B-cells [nTPM]":"84.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"72.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"80.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"98.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"72.8","Single Cell Type RNA - Bipolar cells [nTPM]":"56.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"77.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"75.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"102.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"57.2","Single Cell Type RNA - Club cells [nTPM]":"83.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"68.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"60.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"134.5","Single Cell Type RNA - dendritic cells [nTPM]":"44.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"65.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"54.8","Single Cell Type RNA - Ductal cells [nTPM]":"111.7","Single Cell Type RNA - Early spermatids [nTPM]":"111.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"136.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"92.3","Single Cell Type RNA - Endothelial cells [nTPM]":"63.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"80.8","Single Cell Type RNA - Erythroid cells [nTPM]":"52.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"43.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"72.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"102.2","Single Cell Type RNA - Fibroblasts [nTPM]":"70.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"88.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"88.4","Single Cell Type RNA - granulocytes [nTPM]":"72.2","Single Cell Type RNA - Granulosa cells [nTPM]":"211.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"54.7","Single Cell Type RNA - Hepatocytes [nTPM]":"40.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"123.4","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"42.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"79.7","Single Cell Type RNA - Ionocytes [nTPM]":"107.8","Single Cell Type RNA - Kupffer cells [nTPM]":"108.3","Single Cell Type RNA - Langerhans cells [nTPM]":"87.9","Single Cell Type RNA - Late spermatids [nTPM]":"32.4","Single Cell Type RNA - Leydig cells [nTPM]":"77.9","Single Cell Type RNA - Macrophages [nTPM]":"113.6","Single Cell Type RNA - Melanocytes [nTPM]":"46.2","Single Cell Type RNA - Microglial cells [nTPM]":"30.0","Single Cell Type RNA - monocytes [nTPM]":"153.0","Single Cell Type RNA - Muller glia cells [nTPM]":"71.4","Single Cell Type RNA - NK-cells [nTPM]":"45.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"28.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"31.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"101.1","Single Cell Type RNA - Paneth cells [nTPM]":"101.9","Single Cell Type RNA - Peritubular cells [nTPM]":"72.2","Single Cell Type RNA - Plasma cells [nTPM]":"41.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"77.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"164.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"103.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"188.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"82.6","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"57.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"88.9","Single Cell Type RNA - Spermatocytes [nTPM]":"207.9","Single Cell Type RNA - Spermatogonia [nTPM]":"118.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"101.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"87.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"113.1","Single Cell Type RNA - T-cells [nTPM]":"51.5","Single Cell Type RNA - Theca cells [nTPM]":"95.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"97.6","Single Cell Type RNA - Urothelial cells [nTPM]":"84.5"},{"Gene":"VRK1","Gene synonym":[],"Ensembl":"ENSG00000100749","Gene description":"VRK serine\/threonine kinase 1","Uniprot":["Q99986"],"Chromosome":"14","Position":"96797304-96954846","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell cycle","Cell division","Mitosis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"50.4","testis":"37.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"198.9","Spermatogonia":"110.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000660","HPA017929"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA000660":"AB_1080579","HPA017929":"AB_1858770"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.15e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.9","Tissue RNA - adrenal gland [nTPM]":"5.2","Tissue RNA - amygdala [nTPM]":"5.9","Tissue RNA - appendix [nTPM]":"12.8","Tissue RNA - basal ganglia [nTPM]":"7.1","Tissue RNA - bone marrow [nTPM]":"50.4","Tissue RNA - breast [nTPM]":"11.5","Tissue RNA - cerebellum [nTPM]":"6.0","Tissue RNA - cerebral cortex [nTPM]":"7.9","Tissue RNA - cervix [nTPM]":"5.2","Tissue RNA - choroid plexus [nTPM]":"4.3","Tissue RNA - colon [nTPM]":"10.8","Tissue RNA - duodenum [nTPM]":"6.5","Tissue RNA - endometrium 1 [nTPM]":"6.5","Tissue RNA - epididymis [nTPM]":"6.9","Tissue RNA - esophagus [nTPM]":"8.9","Tissue RNA - fallopian tube [nTPM]":"9.2","Tissue RNA - gallbladder [nTPM]":"4.4","Tissue RNA - heart muscle [nTPM]":"5.2","Tissue RNA - hippocampal formation [nTPM]":"5.9","Tissue RNA - hypothalamus [nTPM]":"5.1","Tissue RNA - kidney [nTPM]":"4.9","Tissue RNA - liver [nTPM]":"5.5","Tissue RNA - lung [nTPM]":"4.9","Tissue RNA - lymph node [nTPM]":"27.1","Tissue RNA - medulla oblongata [nTPM]":"5.3","Tissue RNA - midbrain [nTPM]":"5.5","Tissue RNA - ovary [nTPM]":"6.0","Tissue RNA - pancreas [nTPM]":"3.2","Tissue RNA - parathyroid gland [nTPM]":"5.4","Tissue RNA - pituitary gland [nTPM]":"3.1","Tissue RNA - placenta [nTPM]":"7.6","Tissue RNA - pons [nTPM]":"5.4","Tissue RNA - prostate [nTPM]":"5.0","Tissue RNA - rectum [nTPM]":"12.3","Tissue RNA - retina [nTPM]":"4.4","Tissue RNA - salivary gland [nTPM]":"4.3","Tissue RNA - seminal vesicle [nTPM]":"5.0","Tissue RNA - skeletal muscle [nTPM]":"4.7","Tissue RNA - skin 1 [nTPM]":"7.4","Tissue RNA - small intestine [nTPM]":"7.2","Tissue RNA - smooth muscle [nTPM]":"6.7","Tissue RNA - spinal cord [nTPM]":"4.8","Tissue RNA - spleen [nTPM]":"11.3","Tissue RNA - stomach 1 [nTPM]":"6.5","Tissue RNA - testis [nTPM]":"37.1","Tissue RNA - thalamus [nTPM]":"5.9","Tissue RNA - thymus [nTPM]":"35.5","Tissue RNA - thyroid gland [nTPM]":"5.9","Tissue RNA - tongue [nTPM]":"4.6","Tissue RNA - tonsil [nTPM]":"27.9","Tissue RNA - urinary bladder [nTPM]":"7.7","Tissue RNA - vagina [nTPM]":"5.4","Tissue RNA - white matter [nTPM]":"7.0","Cell RNA - A-431 [nTPM]":"52.4","Cell RNA - A549 [nTPM]":"27.0","Cell RNA - AF22 [nTPM]":"78.5","Cell RNA - AN3-CA [nTPM]":"30.2","Cell RNA - ASC diff [nTPM]":"9.2","Cell RNA - ASC TERT1 [nTPM]":"14.9","Cell RNA - BEWO [nTPM]":"44.8","Cell RNA - BJ [nTPM]":"42.8","Cell RNA - BJ hTERT+ [nTPM]":"34.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"67.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"65.4","Cell RNA - CACO-2 [nTPM]":"36.0","Cell RNA - CAPAN-2 [nTPM]":"54.7","Cell RNA - Daudi [nTPM]":"139.2","Cell RNA - EFO-21 [nTPM]":"22.4","Cell RNA - fHDF\/TERT166 [nTPM]":"24.3","Cell RNA - GAMG [nTPM]":"39.2","Cell RNA - HaCaT [nTPM]":"56.5","Cell RNA - HAP1 [nTPM]":"75.5","Cell RNA - HBEC3-KT [nTPM]":"54.4","Cell RNA - HBF TERT88 [nTPM]":"90.5","Cell RNA - HDLM-2 [nTPM]":"73.4","Cell RNA - HEK 293 [nTPM]":"36.4","Cell RNA - HEL [nTPM]":"90.5","Cell RNA - HeLa [nTPM]":"18.7","Cell RNA - Hep G2 [nTPM]":"39.3","Cell RNA - HHSteC [nTPM]":"10.2","Cell RNA - HL-60 [nTPM]":"168.5","Cell RNA - HMC-1 [nTPM]":"49.2","Cell RNA - HSkMC [nTPM]":"8.5","Cell RNA - hTCEpi [nTPM]":"9.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"50.4","Cell RNA - hTERT-HME1 [nTPM]":"32.6","Cell RNA - hTERT-RPE1 [nTPM]":"12.8","Cell RNA - HUVEC TERT2 [nTPM]":"47.0","Cell RNA - JURKAT [nTPM]":"104.8","Cell RNA - K-562 [nTPM]":"76.6","Cell RNA - Karpas-707 [nTPM]":"79.0","Cell RNA - LHCN-M2 [nTPM]":"56.9","Cell RNA - MCF7 [nTPM]":"65.5","Cell RNA - MOLT-4 [nTPM]":"137.1","Cell RNA - NB-4 [nTPM]":"76.5","Cell RNA - NTERA-2 [nTPM]":"47.8","Cell RNA - OE19 [nTPM]":"39.9","Cell RNA - PC-3 [nTPM]":"59.3","Cell RNA - REH [nTPM]":"124.5","Cell RNA - RH-30 [nTPM]":"134.2","Cell RNA - RPMI-8226 [nTPM]":"48.6","Cell RNA - RPTEC TERT1 [nTPM]":"32.3","Cell RNA - RT4 [nTPM]":"59.3","Cell RNA - SCLC-21H [nTPM]":"53.2","Cell RNA - SH-SY5Y [nTPM]":"28.0","Cell RNA - SiHa [nTPM]":"34.2","Cell RNA - SK-BR-3 [nTPM]":"36.4","Cell RNA - SK-MEL-30 [nTPM]":"30.8","Cell RNA - SuSa [nTPM]":"36.0","Cell RNA - T-47d [nTPM]":"39.3","Cell RNA - THP-1 [nTPM]":"66.6","Cell RNA - TIME [nTPM]":"24.4","Cell RNA - U-138 MG [nTPM]":"27.9","Cell RNA - U-2 OS [nTPM]":"22.8","Cell RNA - U-2197 [nTPM]":"47.7","Cell RNA - U-251 MG [nTPM]":"37.3","Cell RNA - U-266\/70 [nTPM]":"37.7","Cell RNA - U-266\/84 [nTPM]":"53.5","Cell RNA - U-698 [nTPM]":"124.8","Cell RNA - U-87 MG [nTPM]":"44.7","Cell RNA - U-937 [nTPM]":"74.6","Cell RNA - WM-115 [nTPM]":"34.8","Blood RNA - basophil [nTPM]":"42.7","Blood RNA - classical monocyte [nTPM]":"12.3","Blood RNA - eosinophil [nTPM]":"26.2","Blood RNA - gdT-cell [nTPM]":"21.5","Blood RNA - intermediate monocyte [nTPM]":"15.5","Blood RNA - MAIT T-cell [nTPM]":"29.0","Blood RNA - memory B-cell [nTPM]":"31.3","Blood RNA - memory CD4 T-cell [nTPM]":"24.9","Blood RNA - memory CD8 T-cell [nTPM]":"26.4","Blood RNA - myeloid DC [nTPM]":"15.7","Blood RNA - naive B-cell [nTPM]":"32.7","Blood RNA - naive CD4 T-cell [nTPM]":"27.1","Blood RNA - naive CD8 T-cell [nTPM]":"27.3","Blood RNA - neutrophil [nTPM]":"6.5","Blood RNA - NK-cell [nTPM]":"45.6","Blood RNA - non-classical monocyte [nTPM]":"15.2","Blood RNA - plasmacytoid DC [nTPM]":"21.4","Blood RNA - T-reg [nTPM]":"34.9","Blood RNA - total PBMC [nTPM]":"19.4","Brain RNA - amygdala [nTPM]":"5.9","Brain RNA - basal ganglia [nTPM]":"7.1","Brain RNA - cerebellum [nTPM]":"6.0","Brain RNA - cerebral cortex [nTPM]":"7.9","Brain RNA - hippocampal formation [nTPM]":"5.9","Brain RNA - hypothalamus [nTPM]":"5.1","Brain RNA - medulla oblongata [nTPM]":"5.3","Brain RNA - midbrain [nTPM]":"5.5","Brain RNA - pons [nTPM]":"5.4","Brain RNA - spinal cord [nTPM]":"4.8","Brain RNA - thalamus [nTPM]":"5.9","Brain RNA - white matter [nTPM]":"7.0","Single Cell Type RNA - Adipocytes [nTPM]":"15.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.6","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"30.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"23.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"12.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"16.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"34.8","Single Cell Type RNA - dendritic cells [nTPM]":"24.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"13.5","Single Cell Type RNA - Early spermatids [nTPM]":"21.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"21.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.3","Single Cell Type RNA - Endothelial cells [nTPM]":"12.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"76.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"42.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"48.3","Single Cell Type RNA - Fibroblasts [nTPM]":"11.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.8","Single Cell Type RNA - granulocytes [nTPM]":"28.5","Single Cell Type RNA - Granulosa cells [nTPM]":"20.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.1","Single Cell Type RNA - Hepatocytes [nTPM]":"3.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.2","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"36.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.4","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"11.8","Single Cell Type RNA - Langerhans cells [nTPM]":"14.9","Single Cell Type RNA - Late spermatids [nTPM]":"11.5","Single Cell Type RNA - Leydig cells [nTPM]":"5.6","Single Cell Type RNA - Macrophages [nTPM]":"12.0","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"14.2","Single Cell Type RNA - Muller glia cells [nTPM]":"6.2","Single Cell Type RNA - NK-cells [nTPM]":"27.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.3","Single Cell Type RNA - Paneth cells [nTPM]":"2.2","Single Cell Type RNA - Peritubular cells [nTPM]":"9.8","Single Cell Type RNA - Plasma cells [nTPM]":"25.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"37.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.6","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.1","Single Cell Type RNA - Spermatocytes [nTPM]":"198.9","Single Cell Type RNA - Spermatogonia [nTPM]":"110.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.1","Single Cell Type RNA - T-cells [nTPM]":"26.8","Single Cell Type RNA - Theca cells [nTPM]":"9.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.1","Single Cell Type RNA - Urothelial cells [nTPM]":"10.4"},{"Gene":"WARS1","Gene synonym":["IFI53","IFP53","WARS"],"Ensembl":"ENSG00000140105","Gene description":"Tryptophanyl-tRNA synthetase 1","Uniprot":["P23381"],"Chromosome":"14","Position":"100333790-100376805","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Angiogenesis","Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"324.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"66.4","Cytotrophoblasts":"16.5","Endothelial cells":"38.5","Hofbauer cells":"43.1","Syncytiotrophoblasts":"16.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"1345.3","non-classical monocyte":"1608.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HHSteC":"908.5","SK-MEL-30":"1012.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005573","HPA018944"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"49000000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA005573":"AB_2667366","HPA018944":"AB_2669986"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.88e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.94e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-3"},"Tissue RNA - adipose tissue [nTPM]":"100.7","Tissue RNA - adrenal gland [nTPM]":"67.9","Tissue RNA - amygdala [nTPM]":"40.3","Tissue RNA - appendix [nTPM]":"185.6","Tissue RNA - basal ganglia [nTPM]":"44.4","Tissue RNA - bone marrow [nTPM]":"70.5","Tissue RNA - breast [nTPM]":"65.4","Tissue RNA - cerebellum [nTPM]":"40.1","Tissue RNA - cerebral cortex [nTPM]":"45.5","Tissue RNA - cervix [nTPM]":"35.9","Tissue RNA - choroid plexus [nTPM]":"45.2","Tissue RNA - colon [nTPM]":"67.8","Tissue RNA - duodenum [nTPM]":"44.8","Tissue RNA - endometrium 1 [nTPM]":"39.6","Tissue RNA - epididymis [nTPM]":"70.3","Tissue RNA - esophagus [nTPM]":"54.4","Tissue RNA - fallopian tube [nTPM]":"50.8","Tissue RNA - gallbladder [nTPM]":"48.7","Tissue RNA - heart muscle [nTPM]":"157.6","Tissue RNA - hippocampal formation [nTPM]":"44.2","Tissue RNA - hypothalamus [nTPM]":"56.0","Tissue RNA - kidney [nTPM]":"83.6","Tissue RNA - liver [nTPM]":"47.9","Tissue RNA - lung [nTPM]":"207.5","Tissue RNA - lymph node [nTPM]":"139.0","Tissue RNA - medulla oblongata [nTPM]":"72.0","Tissue RNA - midbrain [nTPM]":"52.6","Tissue RNA - ovary [nTPM]":"21.2","Tissue RNA - pancreas [nTPM]":"47.5","Tissue RNA - parathyroid gland [nTPM]":"39.2","Tissue RNA - pituitary gland [nTPM]":"63.4","Tissue RNA - placenta [nTPM]":"324.4","Tissue RNA - pons [nTPM]":"65.3","Tissue RNA - prostate [nTPM]":"49.1","Tissue RNA - rectum [nTPM]":"72.0","Tissue RNA - retina [nTPM]":"37.8","Tissue RNA - salivary gland [nTPM]":"49.5","Tissue RNA - seminal vesicle [nTPM]":"38.3","Tissue RNA - skeletal muscle [nTPM]":"74.7","Tissue RNA - skin 1 [nTPM]":"28.4","Tissue RNA - small intestine [nTPM]":"67.7","Tissue RNA - smooth muscle [nTPM]":"76.2","Tissue RNA - spinal cord [nTPM]":"47.6","Tissue RNA - spleen [nTPM]":"110.6","Tissue RNA - stomach 1 [nTPM]":"70.1","Tissue RNA - testis [nTPM]":"67.7","Tissue RNA - thalamus [nTPM]":"55.0","Tissue RNA - thymus [nTPM]":"61.7","Tissue RNA - thyroid gland [nTPM]":"159.9","Tissue RNA - tongue [nTPM]":"67.0","Tissue RNA - tonsil [nTPM]":"86.2","Tissue RNA - urinary bladder [nTPM]":"107.7","Tissue RNA - vagina [nTPM]":"30.7","Tissue RNA - white matter [nTPM]":"44.9","Cell RNA - A-431 [nTPM]":"91.2","Cell RNA - A549 [nTPM]":"85.7","Cell RNA - AF22 [nTPM]":"54.6","Cell RNA - AN3-CA [nTPM]":"319.1","Cell RNA - ASC diff [nTPM]":"78.7","Cell RNA - ASC TERT1 [nTPM]":"110.7","Cell RNA - BEWO [nTPM]":"87.3","Cell RNA - BJ [nTPM]":"117.4","Cell RNA - BJ hTERT+ [nTPM]":"220.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"232.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"301.4","Cell RNA - CACO-2 [nTPM]":"57.4","Cell RNA - CAPAN-2 [nTPM]":"80.2","Cell RNA - Daudi [nTPM]":"101.7","Cell RNA - EFO-21 [nTPM]":"105.5","Cell RNA - fHDF\/TERT166 [nTPM]":"277.4","Cell RNA - GAMG [nTPM]":"59.7","Cell RNA - HaCaT [nTPM]":"151.1","Cell RNA - HAP1 [nTPM]":"158.8","Cell RNA - HBEC3-KT [nTPM]":"130.3","Cell RNA - HBF TERT88 [nTPM]":"153.1","Cell RNA - HDLM-2 [nTPM]":"154.4","Cell RNA - HEK 293 [nTPM]":"48.3","Cell RNA - HEL [nTPM]":"64.1","Cell RNA - HeLa [nTPM]":"60.9","Cell RNA - Hep G2 [nTPM]":"72.3","Cell RNA - HHSteC [nTPM]":"908.5","Cell RNA - HL-60 [nTPM]":"184.9","Cell RNA - HMC-1 [nTPM]":"101.6","Cell RNA - HSkMC [nTPM]":"126.9","Cell RNA - hTCEpi [nTPM]":"186.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"141.3","Cell RNA - hTERT-HME1 [nTPM]":"290.1","Cell RNA - hTERT-RPE1 [nTPM]":"74.5","Cell RNA - HUVEC TERT2 [nTPM]":"225.0","Cell RNA - JURKAT [nTPM]":"66.1","Cell RNA - K-562 [nTPM]":"202.8","Cell RNA - Karpas-707 [nTPM]":"255.0","Cell RNA - LHCN-M2 [nTPM]":"107.5","Cell RNA - MCF7 [nTPM]":"178.0","Cell RNA - MOLT-4 [nTPM]":"64.3","Cell RNA - NB-4 [nTPM]":"87.1","Cell RNA - NTERA-2 [nTPM]":"55.4","Cell RNA - OE19 [nTPM]":"94.1","Cell RNA - PC-3 [nTPM]":"152.2","Cell RNA - REH [nTPM]":"51.4","Cell RNA - RH-30 [nTPM]":"86.5","Cell RNA - RPMI-8226 [nTPM]":"64.9","Cell RNA - RPTEC TERT1 [nTPM]":"119.3","Cell RNA - RT4 [nTPM]":"80.8","Cell RNA - SCLC-21H [nTPM]":"145.7","Cell RNA - SH-SY5Y [nTPM]":"84.9","Cell RNA - SiHa [nTPM]":"69.4","Cell RNA - SK-BR-3 [nTPM]":"58.7","Cell RNA - SK-MEL-30 [nTPM]":"1012.4","Cell RNA - SuSa [nTPM]":"70.5","Cell RNA - T-47d [nTPM]":"153.6","Cell RNA - THP-1 [nTPM]":"234.7","Cell RNA - TIME [nTPM]":"153.1","Cell RNA - U-138 MG [nTPM]":"25.7","Cell RNA - U-2 OS [nTPM]":"58.9","Cell RNA - U-2197 [nTPM]":"269.2","Cell RNA - U-251 MG [nTPM]":"61.3","Cell RNA - U-266\/70 [nTPM]":"446.4","Cell RNA - U-266\/84 [nTPM]":"277.1","Cell RNA - U-698 [nTPM]":"191.9","Cell RNA - U-87 MG [nTPM]":"295.0","Cell RNA - U-937 [nTPM]":"144.2","Cell RNA - WM-115 [nTPM]":"205.5","Blood RNA - basophil [nTPM]":"96.5","Blood RNA - classical monocyte [nTPM]":"471.7","Blood RNA - eosinophil [nTPM]":"610.4","Blood RNA - gdT-cell [nTPM]":"41.5","Blood RNA - intermediate monocyte [nTPM]":"1345.3","Blood RNA - MAIT T-cell [nTPM]":"38.4","Blood RNA - memory B-cell [nTPM]":"71.4","Blood RNA - memory CD4 T-cell [nTPM]":"34.5","Blood RNA - memory CD8 T-cell [nTPM]":"38.4","Blood RNA - myeloid DC [nTPM]":"337.9","Blood RNA - naive B-cell [nTPM]":"68.0","Blood RNA - naive CD4 T-cell [nTPM]":"24.8","Blood RNA - naive CD8 T-cell [nTPM]":"28.6","Blood RNA - neutrophil [nTPM]":"170.9","Blood RNA - NK-cell [nTPM]":"44.5","Blood RNA - non-classical monocyte [nTPM]":"1608.2","Blood RNA - plasmacytoid DC [nTPM]":"54.7","Blood RNA - T-reg [nTPM]":"44.8","Blood RNA - total PBMC [nTPM]":"672.7","Brain RNA - amygdala [nTPM]":"40.3","Brain RNA - basal ganglia [nTPM]":"44.4","Brain RNA - cerebellum [nTPM]":"40.1","Brain RNA - cerebral cortex [nTPM]":"45.5","Brain RNA - hippocampal formation [nTPM]":"44.2","Brain RNA - hypothalamus [nTPM]":"56.0","Brain RNA - medulla oblongata [nTPM]":"72.0","Brain RNA - midbrain [nTPM]":"52.6","Brain RNA - pons [nTPM]":"65.3","Brain RNA - spinal cord [nTPM]":"47.6","Brain RNA - thalamus [nTPM]":"55.0","Brain RNA - white matter [nTPM]":"44.9","Single Cell Type RNA - Adipocytes [nTPM]":"66.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.5","Single Cell Type RNA - dendritic cells [nTPM]":"3.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"38.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.5","Single Cell Type RNA - Fibroblasts [nTPM]":"5.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"43.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"9.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"4.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.6","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"WARS2","Gene synonym":["mtTrpRS"],"Ensembl":"ENSG00000116874","Gene description":"Tryptophanyl tRNA synthetase 2, mitochondrial","Uniprot":["Q9UGM6"],"Chromosome":"1","Position":"119031216-119140654","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"57.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028007","HPA069692"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA028007":null,"HPA069692":"AB_2686172"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.76e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.45e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.3","Tissue RNA - adrenal gland [nTPM]":"8.8","Tissue RNA - amygdala [nTPM]":"2.4","Tissue RNA - appendix [nTPM]":"4.1","Tissue RNA - basal ganglia [nTPM]":"2.4","Tissue RNA - bone marrow [nTPM]":"1.9","Tissue RNA - breast [nTPM]":"9.4","Tissue RNA - cerebellum [nTPM]":"2.4","Tissue RNA - cerebral cortex [nTPM]":"3.0","Tissue RNA - cervix [nTPM]":"6.9","Tissue RNA - choroid plexus [nTPM]":"6.5","Tissue RNA - colon [nTPM]":"7.3","Tissue RNA - duodenum [nTPM]":"7.7","Tissue RNA - endometrium 1 [nTPM]":"6.3","Tissue RNA - epididymis [nTPM]":"3.8","Tissue RNA - esophagus [nTPM]":"6.1","Tissue RNA - fallopian tube [nTPM]":"9.4","Tissue RNA - gallbladder [nTPM]":"4.9","Tissue RNA - heart muscle [nTPM]":"7.9","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"2.6","Tissue RNA - kidney [nTPM]":"9.6","Tissue RNA - liver [nTPM]":"6.1","Tissue RNA - lung [nTPM]":"5.0","Tissue RNA - lymph node [nTPM]":"4.7","Tissue RNA - medulla oblongata [nTPM]":"2.4","Tissue RNA - midbrain [nTPM]":"2.4","Tissue RNA - ovary [nTPM]":"8.2","Tissue RNA - pancreas [nTPM]":"8.9","Tissue RNA - parathyroid gland [nTPM]":"10.2","Tissue RNA - pituitary gland [nTPM]":"3.8","Tissue RNA - placenta [nTPM]":"6.3","Tissue RNA - pons [nTPM]":"2.4","Tissue RNA - prostate [nTPM]":"5.7","Tissue RNA - rectum [nTPM]":"8.0","Tissue RNA - retina [nTPM]":"6.0","Tissue RNA - salivary gland [nTPM]":"5.4","Tissue RNA - seminal vesicle [nTPM]":"3.5","Tissue RNA - skeletal muscle [nTPM]":"6.3","Tissue RNA - skin 1 [nTPM]":"5.2","Tissue RNA - small intestine [nTPM]":"5.1","Tissue RNA - smooth muscle [nTPM]":"5.2","Tissue RNA - spinal cord [nTPM]":"2.4","Tissue RNA - spleen [nTPM]":"3.0","Tissue RNA - stomach 1 [nTPM]":"7.2","Tissue RNA - testis [nTPM]":"4.6","Tissue RNA - thalamus [nTPM]":"2.3","Tissue RNA - thymus [nTPM]":"4.6","Tissue RNA - thyroid gland [nTPM]":"6.8","Tissue RNA - tongue [nTPM]":"6.5","Tissue RNA - tonsil [nTPM]":"5.1","Tissue RNA - urinary bladder [nTPM]":"6.8","Tissue RNA - vagina [nTPM]":"5.6","Tissue RNA - white matter [nTPM]":"2.8","Cell RNA - A-431 [nTPM]":"12.8","Cell RNA - A549 [nTPM]":"5.0","Cell RNA - AF22 [nTPM]":"7.5","Cell RNA - AN3-CA [nTPM]":"7.9","Cell RNA - ASC diff [nTPM]":"9.6","Cell RNA - ASC TERT1 [nTPM]":"21.6","Cell RNA - BEWO [nTPM]":"7.6","Cell RNA - BJ [nTPM]":"7.0","Cell RNA - BJ hTERT+ [nTPM]":"10.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.1","Cell RNA - CACO-2 [nTPM]":"14.4","Cell RNA - CAPAN-2 [nTPM]":"5.6","Cell RNA - Daudi [nTPM]":"19.0","Cell RNA - EFO-21 [nTPM]":"11.4","Cell RNA - fHDF\/TERT166 [nTPM]":"12.0","Cell RNA - GAMG [nTPM]":"4.2","Cell RNA - HaCaT [nTPM]":"8.2","Cell RNA - HAP1 [nTPM]":"13.9","Cell RNA - HBEC3-KT [nTPM]":"12.6","Cell RNA - HBF TERT88 [nTPM]":"11.7","Cell RNA - HDLM-2 [nTPM]":"9.8","Cell RNA - HEK 293 [nTPM]":"16.6","Cell RNA - HEL [nTPM]":"8.9","Cell RNA - HeLa [nTPM]":"12.8","Cell RNA - Hep G2 [nTPM]":"13.9","Cell RNA - HHSteC [nTPM]":"19.6","Cell RNA - HL-60 [nTPM]":"14.8","Cell RNA - HMC-1 [nTPM]":"4.8","Cell RNA - HSkMC [nTPM]":"16.1","Cell RNA - hTCEpi [nTPM]":"9.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.1","Cell RNA - hTERT-HME1 [nTPM]":"20.2","Cell RNA - hTERT-RPE1 [nTPM]":"10.0","Cell RNA - HUVEC TERT2 [nTPM]":"11.7","Cell RNA - JURKAT [nTPM]":"7.9","Cell RNA - K-562 [nTPM]":"14.1","Cell RNA - Karpas-707 [nTPM]":"13.4","Cell RNA - LHCN-M2 [nTPM]":"14.4","Cell RNA - MCF7 [nTPM]":"15.7","Cell RNA - MOLT-4 [nTPM]":"8.9","Cell RNA - NB-4 [nTPM]":"8.6","Cell RNA - NTERA-2 [nTPM]":"9.9","Cell RNA - OE19 [nTPM]":"9.8","Cell RNA - PC-3 [nTPM]":"10.6","Cell RNA - REH [nTPM]":"6.3","Cell RNA - RH-30 [nTPM]":"24.9","Cell RNA - RPMI-8226 [nTPM]":"9.9","Cell RNA - RPTEC TERT1 [nTPM]":"20.9","Cell RNA - RT4 [nTPM]":"17.5","Cell RNA - SCLC-21H [nTPM]":"10.7","Cell RNA - SH-SY5Y [nTPM]":"6.6","Cell RNA - SiHa [nTPM]":"11.3","Cell RNA - SK-BR-3 [nTPM]":"15.4","Cell RNA - SK-MEL-30 [nTPM]":"16.7","Cell RNA - SuSa [nTPM]":"13.1","Cell RNA - T-47d [nTPM]":"6.9","Cell RNA - THP-1 [nTPM]":"11.1","Cell RNA - TIME [nTPM]":"8.8","Cell RNA - U-138 MG [nTPM]":"7.8","Cell RNA - U-2 OS [nTPM]":"9.2","Cell RNA - U-2197 [nTPM]":"15.2","Cell RNA - U-251 MG [nTPM]":"13.8","Cell RNA - U-266\/70 [nTPM]":"6.4","Cell RNA - U-266\/84 [nTPM]":"4.6","Cell RNA - U-698 [nTPM]":"8.3","Cell RNA - U-87 MG [nTPM]":"9.6","Cell RNA - U-937 [nTPM]":"12.1","Cell RNA - WM-115 [nTPM]":"14.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"5.0","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"3.4","Blood RNA - intermediate monocyte [nTPM]":"3.6","Blood RNA - MAIT T-cell [nTPM]":"5.0","Blood RNA - memory B-cell [nTPM]":"4.6","Blood RNA - memory CD4 T-cell [nTPM]":"3.6","Blood RNA - memory CD8 T-cell [nTPM]":"4.5","Blood RNA - myeloid DC [nTPM]":"6.7","Blood RNA - naive B-cell [nTPM]":"6.2","Blood RNA - naive CD4 T-cell [nTPM]":"4.2","Blood RNA - naive CD8 T-cell [nTPM]":"4.2","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"4.2","Blood RNA - non-classical monocyte [nTPM]":"2.2","Blood RNA - plasmacytoid DC [nTPM]":"3.2","Blood RNA - T-reg [nTPM]":"4.5","Blood RNA - total PBMC [nTPM]":"3.4","Brain RNA - amygdala [nTPM]":"2.4","Brain RNA - basal ganglia [nTPM]":"2.4","Brain RNA - cerebellum [nTPM]":"2.4","Brain RNA - cerebral cortex [nTPM]":"3.0","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"2.6","Brain RNA - medulla oblongata [nTPM]":"2.4","Brain RNA - midbrain [nTPM]":"2.4","Brain RNA - pons [nTPM]":"2.4","Brain RNA - spinal cord [nTPM]":"2.4","Brain RNA - thalamus [nTPM]":"2.3","Brain RNA - white matter [nTPM]":"2.8","Single Cell Type RNA - Adipocytes [nTPM]":"7.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.3","Single Cell Type RNA - Astrocytes [nTPM]":"22.5","Single Cell Type RNA - B-cells [nTPM]":"10.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"6.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"11.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.9","Single Cell Type RNA - dendritic cells [nTPM]":"7.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"9.8","Single Cell Type RNA - Early spermatids [nTPM]":"57.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.6","Single Cell Type RNA - Endothelial cells [nTPM]":"7.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"18.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.3","Single Cell Type RNA - Fibroblasts [nTPM]":"15.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.8","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"9.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"7.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.5","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.2","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"10.0","Single Cell Type RNA - Langerhans cells [nTPM]":"6.9","Single Cell Type RNA - Late spermatids [nTPM]":"31.8","Single Cell Type RNA - Leydig cells [nTPM]":"9.9","Single Cell Type RNA - Macrophages [nTPM]":"8.2","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"13.0","Single Cell Type RNA - Muller glia cells [nTPM]":"5.0","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.7","Single Cell Type RNA - Paneth cells [nTPM]":"6.1","Single Cell Type RNA - Peritubular cells [nTPM]":"8.2","Single Cell Type RNA - Plasma cells [nTPM]":"9.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.1","Single Cell Type RNA - Spermatocytes [nTPM]":"5.4","Single Cell Type RNA - Spermatogonia [nTPM]":"6.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.0","Single Cell Type RNA - T-cells [nTPM]":"10.2","Single Cell Type RNA - Theca cells [nTPM]":"19.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.8","Single Cell Type RNA - Urothelial cells [nTPM]":"14.4"},{"Gene":"WASHC4","Gene synonym":["KIAA1033","SWIP"],"Ensembl":"ENSG00000136051","Gene description":"WASH complex subunit 4","Uniprot":["Q2M389"],"Chromosome":"12","Position":"105107324-105169130","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"44.1","Endometrial stromal cells":"48.3","Hofbauer cells":"51.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045666","HPA046737"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA045666":"AB_2679411","HPA046737":"AB_2679778"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.02e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Tissue RNA - adipose tissue [nTPM]":"22.4","Tissue RNA - adrenal gland [nTPM]":"21.1","Tissue RNA - amygdala [nTPM]":"9.4","Tissue RNA - appendix [nTPM]":"30.9","Tissue RNA - basal ganglia [nTPM]":"13.8","Tissue RNA - bone marrow [nTPM]":"23.8","Tissue RNA - breast [nTPM]":"20.8","Tissue RNA - cerebellum [nTPM]":"13.8","Tissue RNA - cerebral cortex [nTPM]":"12.2","Tissue RNA - cervix [nTPM]":"20.7","Tissue RNA - choroid plexus [nTPM]":"11.8","Tissue RNA - colon [nTPM]":"16.1","Tissue RNA - duodenum [nTPM]":"15.3","Tissue RNA - endometrium 1 [nTPM]":"20.1","Tissue RNA - epididymis [nTPM]":"19.9","Tissue RNA - esophagus [nTPM]":"15.1","Tissue RNA - fallopian tube [nTPM]":"13.1","Tissue RNA - gallbladder [nTPM]":"22.6","Tissue RNA - heart muscle [nTPM]":"14.3","Tissue RNA - hippocampal formation [nTPM]":"9.1","Tissue RNA - hypothalamus [nTPM]":"13.8","Tissue RNA - kidney [nTPM]":"23.5","Tissue RNA - liver [nTPM]":"29.7","Tissue RNA - lung [nTPM]":"20.2","Tissue RNA - lymph node [nTPM]":"44.0","Tissue RNA - medulla oblongata [nTPM]":"17.8","Tissue RNA - midbrain [nTPM]":"13.0","Tissue RNA - ovary [nTPM]":"22.8","Tissue RNA - pancreas [nTPM]":"18.3","Tissue RNA - parathyroid gland [nTPM]":"20.4","Tissue RNA - pituitary gland [nTPM]":"8.5","Tissue RNA - placenta [nTPM]":"30.5","Tissue RNA - pons [nTPM]":"18.4","Tissue RNA - prostate [nTPM]":"19.2","Tissue RNA - rectum [nTPM]":"18.4","Tissue RNA - retina [nTPM]":"15.4","Tissue RNA - salivary gland [nTPM]":"16.1","Tissue RNA - seminal vesicle [nTPM]":"15.8","Tissue RNA - skeletal muscle [nTPM]":"12.2","Tissue RNA - skin 1 [nTPM]":"31.2","Tissue RNA - small intestine [nTPM]":"18.4","Tissue RNA - smooth muscle [nTPM]":"19.8","Tissue RNA - spinal cord [nTPM]":"15.2","Tissue RNA - spleen [nTPM]":"32.9","Tissue RNA - stomach 1 [nTPM]":"17.9","Tissue RNA - testis [nTPM]":"12.1","Tissue RNA - thalamus [nTPM]":"14.5","Tissue RNA - thymus [nTPM]":"18.0","Tissue RNA - thyroid gland [nTPM]":"22.1","Tissue RNA - tongue [nTPM]":"14.2","Tissue RNA - tonsil [nTPM]":"39.5","Tissue RNA - urinary bladder [nTPM]":"17.6","Tissue RNA - vagina [nTPM]":"12.6","Tissue RNA - white matter [nTPM]":"22.1","Cell RNA - A-431 [nTPM]":"24.0","Cell RNA - A549 [nTPM]":"28.2","Cell RNA - AF22 [nTPM]":"24.6","Cell RNA - AN3-CA [nTPM]":"18.2","Cell RNA - ASC diff [nTPM]":"56.3","Cell RNA - ASC TERT1 [nTPM]":"56.6","Cell RNA - BEWO [nTPM]":"29.5","Cell RNA - BJ [nTPM]":"36.5","Cell RNA - BJ hTERT+ [nTPM]":"41.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"41.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"38.0","Cell RNA - CACO-2 [nTPM]":"20.2","Cell RNA - CAPAN-2 [nTPM]":"13.5","Cell RNA - Daudi [nTPM]":"53.4","Cell RNA - EFO-21 [nTPM]":"19.8","Cell RNA - fHDF\/TERT166 [nTPM]":"61.0","Cell RNA - GAMG [nTPM]":"26.5","Cell RNA - HaCaT [nTPM]":"21.9","Cell RNA - HAP1 [nTPM]":"21.5","Cell RNA - HBEC3-KT [nTPM]":"22.3","Cell RNA - HBF TERT88 [nTPM]":"33.5","Cell RNA - HDLM-2 [nTPM]":"19.2","Cell RNA - HEK 293 [nTPM]":"15.3","Cell RNA - HEL [nTPM]":"11.1","Cell RNA - HeLa [nTPM]":"25.6","Cell RNA - Hep G2 [nTPM]":"16.8","Cell RNA - HHSteC [nTPM]":"38.4","Cell RNA - HL-60 [nTPM]":"30.9","Cell RNA - HMC-1 [nTPM]":"20.5","Cell RNA - HSkMC [nTPM]":"45.7","Cell RNA - hTCEpi [nTPM]":"25.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"37.3","Cell RNA - hTERT-HME1 [nTPM]":"30.4","Cell RNA - hTERT-RPE1 [nTPM]":"45.1","Cell RNA - HUVEC TERT2 [nTPM]":"68.7","Cell RNA - JURKAT [nTPM]":"18.1","Cell RNA - K-562 [nTPM]":"22.1","Cell RNA - Karpas-707 [nTPM]":"18.6","Cell RNA - LHCN-M2 [nTPM]":"45.9","Cell RNA - MCF7 [nTPM]":"12.1","Cell RNA - MOLT-4 [nTPM]":"17.1","Cell RNA - NB-4 [nTPM]":"32.6","Cell RNA - NTERA-2 [nTPM]":"30.1","Cell RNA - OE19 [nTPM]":"16.8","Cell RNA - PC-3 [nTPM]":"23.5","Cell RNA - REH [nTPM]":"32.7","Cell RNA - RH-30 [nTPM]":"32.8","Cell RNA - RPMI-8226 [nTPM]":"16.6","Cell RNA - RPTEC TERT1 [nTPM]":"55.6","Cell RNA - RT4 [nTPM]":"27.5","Cell RNA - SCLC-21H [nTPM]":"15.4","Cell RNA - SH-SY5Y [nTPM]":"19.0","Cell RNA - SiHa [nTPM]":"37.7","Cell RNA - SK-BR-3 [nTPM]":"26.4","Cell RNA - SK-MEL-30 [nTPM]":"37.9","Cell RNA - SuSa [nTPM]":"31.0","Cell RNA - T-47d [nTPM]":"19.6","Cell RNA - THP-1 [nTPM]":"32.9","Cell RNA - TIME [nTPM]":"84.1","Cell RNA - U-138 MG [nTPM]":"49.8","Cell RNA - U-2 OS [nTPM]":"13.6","Cell RNA - U-2197 [nTPM]":"32.1","Cell RNA - U-251 MG [nTPM]":"23.9","Cell RNA - U-266\/70 [nTPM]":"23.3","Cell RNA - U-266\/84 [nTPM]":"23.9","Cell RNA - U-698 [nTPM]":"42.7","Cell RNA - U-87 MG [nTPM]":"35.4","Cell RNA - U-937 [nTPM]":"26.1","Cell RNA - WM-115 [nTPM]":"51.4","Blood RNA - basophil [nTPM]":"21.3","Blood RNA - classical monocyte [nTPM]":"15.1","Blood RNA - eosinophil [nTPM]":"9.2","Blood RNA - gdT-cell [nTPM]":"3.0","Blood RNA - intermediate monocyte [nTPM]":"18.4","Blood RNA - MAIT T-cell [nTPM]":"4.4","Blood RNA - memory B-cell [nTPM]":"16.2","Blood RNA - memory CD4 T-cell [nTPM]":"4.7","Blood RNA - memory CD8 T-cell [nTPM]":"4.1","Blood RNA - myeloid DC [nTPM]":"11.9","Blood RNA - naive B-cell [nTPM]":"12.9","Blood RNA - naive CD4 T-cell [nTPM]":"4.9","Blood RNA - naive CD8 T-cell [nTPM]":"4.7","Blood RNA - neutrophil [nTPM]":"16.7","Blood RNA - NK-cell [nTPM]":"8.0","Blood RNA - non-classical monocyte [nTPM]":"34.2","Blood RNA - plasmacytoid DC [nTPM]":"5.8","Blood RNA - T-reg [nTPM]":"3.5","Blood RNA - total PBMC [nTPM]":"6.9","Brain RNA - amygdala [nTPM]":"9.4","Brain RNA - basal ganglia [nTPM]":"13.8","Brain RNA - cerebellum [nTPM]":"13.8","Brain RNA - cerebral cortex [nTPM]":"12.2","Brain RNA - hippocampal formation [nTPM]":"9.1","Brain RNA - hypothalamus [nTPM]":"13.8","Brain RNA - medulla oblongata [nTPM]":"17.8","Brain RNA - midbrain [nTPM]":"13.0","Brain RNA - pons [nTPM]":"18.4","Brain RNA - spinal cord [nTPM]":"15.2","Brain RNA - thalamus [nTPM]":"14.5","Brain RNA - white matter [nTPM]":"22.1","Single Cell Type RNA - Adipocytes [nTPM]":"37.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"24.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"25.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"11.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"24.1","Single Cell Type RNA - dendritic cells [nTPM]":"17.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"25.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"48.3","Single Cell Type RNA - Endothelial cells [nTPM]":"18.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"22.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"28.0","Single Cell Type RNA - Fibroblasts [nTPM]":"14.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"31.7","Single Cell Type RNA - granulocytes [nTPM]":"26.5","Single Cell Type RNA - Granulosa cells [nTPM]":"30.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"51.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"36.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"26.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"24.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"5.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"41.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"32.0","Single Cell Type RNA - T-cells [nTPM]":"8.9","Single Cell Type RNA - Theca cells [nTPM]":"29.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"WEE2","Gene synonym":["FLJ16107","WEE1B"],"Ensembl":"ENSG00000214102","Gene description":"WEE2 oocyte meiosis inhibiting kinase","Uniprot":["P0C1S8"],"Chromosome":"7","Position":"141708353-141731271","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Meiosis"],"Molecular function":["Kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Distal tubular cells":"1.9","Proximal tubular cells":"2.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"CACO-2":"3.1"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027418","HPA054280"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA027418":"AB_10603144","HPA054280":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"3.1","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.6","Cell RNA - SiHa [nTPM]":"0.4","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.6","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"WFS1","Gene synonym":["DFNA14","DFNA38","DFNA6","DIDMOAD","WFS"],"Ensembl":"ENSG00000109501","Gene description":"Wolframin ER transmembrane glycoprotein","Uniprot":["O76024"],"Chromosome":"4","Position":"6269849-6303265","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cataract","Deafness","Diabetes insipidus","Diabetes mellitus","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"131.4","Extravillous trophoblasts":"120.2","Granulosa cells":"71.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"100.4","Hep G2":"83.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029128"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029128":"AB_10603460"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.13e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.13e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Tissue RNA - adipose tissue [nTPM]":"39.4","Tissue RNA - adrenal gland [nTPM]":"20.2","Tissue RNA - amygdala [nTPM]":"43.7","Tissue RNA - appendix [nTPM]":"6.8","Tissue RNA - basal ganglia [nTPM]":"71.2","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"36.0","Tissue RNA - cerebellum [nTPM]":"34.3","Tissue RNA - cerebral cortex [nTPM]":"47.2","Tissue RNA - cervix [nTPM]":"51.9","Tissue RNA - choroid plexus [nTPM]":"34.5","Tissue RNA - colon [nTPM]":"44.8","Tissue RNA - duodenum [nTPM]":"12.2","Tissue RNA - endometrium 1 [nTPM]":"75.4","Tissue RNA - epididymis [nTPM]":"14.0","Tissue RNA - esophagus [nTPM]":"11.3","Tissue RNA - fallopian tube [nTPM]":"58.6","Tissue RNA - gallbladder [nTPM]":"12.4","Tissue RNA - heart muscle [nTPM]":"64.3","Tissue RNA - hippocampal formation [nTPM]":"35.9","Tissue RNA - hypothalamus [nTPM]":"36.8","Tissue RNA - kidney [nTPM]":"16.8","Tissue RNA - liver [nTPM]":"17.1","Tissue RNA - lung [nTPM]":"43.8","Tissue RNA - lymph node [nTPM]":"5.9","Tissue RNA - medulla oblongata [nTPM]":"34.4","Tissue RNA - midbrain [nTPM]":"43.7","Tissue RNA - ovary [nTPM]":"87.1","Tissue RNA - pancreas [nTPM]":"20.1","Tissue RNA - parathyroid gland [nTPM]":"7.2","Tissue RNA - pituitary gland [nTPM]":"50.2","Tissue RNA - placenta [nTPM]":"16.6","Tissue RNA - pons [nTPM]":"36.6","Tissue RNA - prostate [nTPM]":"34.6","Tissue RNA - rectum [nTPM]":"3.4","Tissue RNA - retina [nTPM]":"6.9","Tissue RNA - salivary gland [nTPM]":"14.6","Tissue RNA - seminal vesicle [nTPM]":"36.3","Tissue RNA - skeletal muscle [nTPM]":"16.0","Tissue RNA - skin 1 [nTPM]":"26.8","Tissue RNA - small intestine [nTPM]":"22.0","Tissue RNA - smooth muscle [nTPM]":"17.0","Tissue RNA - spinal cord [nTPM]":"33.7","Tissue RNA - spleen [nTPM]":"29.3","Tissue RNA - stomach 1 [nTPM]":"29.1","Tissue RNA - testis [nTPM]":"31.8","Tissue RNA - thalamus [nTPM]":"44.1","Tissue RNA - thymus [nTPM]":"2.9","Tissue RNA - thyroid gland [nTPM]":"48.1","Tissue RNA - tongue [nTPM]":"7.5","Tissue RNA - tonsil [nTPM]":"2.3","Tissue RNA - urinary bladder [nTPM]":"57.8","Tissue RNA - vagina [nTPM]":"29.1","Tissue RNA - white matter [nTPM]":"32.1","Cell RNA - A-431 [nTPM]":"14.1","Cell RNA - A549 [nTPM]":"35.3","Cell RNA - AF22 [nTPM]":"9.1","Cell RNA - AN3-CA [nTPM]":"33.9","Cell RNA - ASC diff [nTPM]":"37.2","Cell RNA - ASC TERT1 [nTPM]":"10.2","Cell RNA - BEWO [nTPM]":"100.4","Cell RNA - BJ [nTPM]":"23.0","Cell RNA - BJ hTERT+ [nTPM]":"32.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.6","Cell RNA - CACO-2 [nTPM]":"24.8","Cell RNA - CAPAN-2 [nTPM]":"37.2","Cell RNA - Daudi [nTPM]":"5.5","Cell RNA - EFO-21 [nTPM]":"34.3","Cell RNA - fHDF\/TERT166 [nTPM]":"26.3","Cell RNA - GAMG [nTPM]":"74.8","Cell RNA - HaCaT [nTPM]":"8.0","Cell RNA - HAP1 [nTPM]":"6.8","Cell RNA - HBEC3-KT [nTPM]":"14.2","Cell RNA - HBF TERT88 [nTPM]":"6.4","Cell RNA - HDLM-2 [nTPM]":"5.7","Cell RNA - HEK 293 [nTPM]":"14.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"11.0","Cell RNA - Hep G2 [nTPM]":"83.0","Cell RNA - HHSteC [nTPM]":"34.5","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.1","Cell RNA - HSkMC [nTPM]":"33.7","Cell RNA - hTCEpi [nTPM]":"18.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.0","Cell RNA - hTERT-HME1 [nTPM]":"13.6","Cell RNA - hTERT-RPE1 [nTPM]":"12.3","Cell RNA - HUVEC TERT2 [nTPM]":"25.3","Cell RNA - JURKAT [nTPM]":"2.5","Cell RNA - K-562 [nTPM]":"0.6","Cell RNA - Karpas-707 [nTPM]":"24.3","Cell RNA - LHCN-M2 [nTPM]":"9.7","Cell RNA - MCF7 [nTPM]":"28.0","Cell RNA - MOLT-4 [nTPM]":"1.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"13.5","Cell RNA - OE19 [nTPM]":"20.3","Cell RNA - PC-3 [nTPM]":"38.0","Cell RNA - REH [nTPM]":"3.4","Cell RNA - RH-30 [nTPM]":"9.6","Cell RNA - RPMI-8226 [nTPM]":"7.5","Cell RNA - RPTEC TERT1 [nTPM]":"6.7","Cell RNA - RT4 [nTPM]":"52.4","Cell RNA - SCLC-21H [nTPM]":"6.1","Cell RNA - SH-SY5Y [nTPM]":"15.4","Cell RNA - SiHa [nTPM]":"12.2","Cell RNA - SK-BR-3 [nTPM]":"17.4","Cell RNA - SK-MEL-30 [nTPM]":"13.1","Cell RNA - SuSa [nTPM]":"9.6","Cell RNA - T-47d [nTPM]":"31.5","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"19.9","Cell RNA - U-138 MG [nTPM]":"19.8","Cell RNA - U-2 OS [nTPM]":"22.8","Cell RNA - U-2197 [nTPM]":"19.1","Cell RNA - U-251 MG [nTPM]":"14.8","Cell RNA - U-266\/70 [nTPM]":"26.0","Cell RNA - U-266\/84 [nTPM]":"10.1","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"23.9","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"18.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.7","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"2.7","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"3.9","Blood RNA - memory B-cell [nTPM]":"2.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"2.1","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"1.1","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"43.7","Brain RNA - basal ganglia [nTPM]":"71.2","Brain RNA - cerebellum [nTPM]":"34.3","Brain RNA - cerebral cortex [nTPM]":"47.2","Brain RNA - hippocampal formation [nTPM]":"35.9","Brain RNA - hypothalamus [nTPM]":"36.8","Brain RNA - medulla oblongata [nTPM]":"34.4","Brain RNA - midbrain [nTPM]":"43.7","Brain RNA - pons [nTPM]":"36.6","Brain RNA - spinal cord [nTPM]":"33.7","Brain RNA - thalamus [nTPM]":"44.1","Brain RNA - white matter [nTPM]":"32.1","Single Cell Type RNA - Adipocytes [nTPM]":"38.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"131.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.4","Single Cell Type RNA - Astrocytes [nTPM]":"40.5","Single Cell Type RNA - B-cells [nTPM]":"3.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"4.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"42.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"5.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"22.2","Single Cell Type RNA - dendritic cells [nTPM]":"1.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.5","Single Cell Type RNA - Early spermatids [nTPM]":"10.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.6","Single Cell Type RNA - Endothelial cells [nTPM]":"21.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"33.5","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"120.2","Single Cell Type RNA - Fibroblasts [nTPM]":"15.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"71.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.4","Single Cell Type RNA - Hepatocytes [nTPM]":"10.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.7","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"2.4","Single Cell Type RNA - Late spermatids [nTPM]":"19.1","Single Cell Type RNA - Leydig cells [nTPM]":"40.0","Single Cell Type RNA - Macrophages [nTPM]":"2.5","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"31.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.9","Single Cell Type RNA - Paneth cells [nTPM]":"1.6","Single Cell Type RNA - Peritubular cells [nTPM]":"57.9","Single Cell Type RNA - Plasma cells [nTPM]":"19.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.1","Single Cell Type RNA - Spermatocytes [nTPM]":"10.8","Single Cell Type RNA - Spermatogonia [nTPM]":"14.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"39.7","Single Cell Type RNA - T-cells [nTPM]":"1.6","Single Cell Type RNA - Theca cells [nTPM]":"11.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.7","Single Cell Type RNA - Urothelial cells [nTPM]":"2.1"},{"Gene":"WNK1","Gene synonym":["HSAN2","HSN2","PPP1R167","PRKWNK1"],"Ensembl":"ENSG00000060237","Gene description":"WNK lysine deficient protein kinase 1","Uniprot":["Q9H4A3"],"Chromosome":"12","Position":"752579-911452","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Protein kinase inhibitor","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"293.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"336.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046541","HPA059157"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"92000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA046541":"AB_2679690","HPA059157":"AB_2683935"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.67e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Tissue RNA - adipose tissue [nTPM]":"56.7","Tissue RNA - adrenal gland [nTPM]":"20.6","Tissue RNA - amygdala [nTPM]":"190.8","Tissue RNA - appendix [nTPM]":"36.4","Tissue RNA - basal ganglia [nTPM]":"236.8","Tissue RNA - bone marrow [nTPM]":"54.2","Tissue RNA - breast [nTPM]":"33.5","Tissue RNA - cerebellum [nTPM]":"179.4","Tissue RNA - cerebral cortex [nTPM]":"166.1","Tissue RNA - cervix [nTPM]":"32.8","Tissue RNA - choroid plexus [nTPM]":"110.8","Tissue RNA - colon [nTPM]":"22.8","Tissue RNA - duodenum [nTPM]":"14.4","Tissue RNA - endometrium 1 [nTPM]":"26.7","Tissue RNA - epididymis [nTPM]":"30.4","Tissue RNA - esophagus [nTPM]":"72.1","Tissue RNA - fallopian tube [nTPM]":"29.4","Tissue RNA - gallbladder [nTPM]":"27.1","Tissue RNA - heart muscle [nTPM]":"63.8","Tissue RNA - hippocampal formation [nTPM]":"132.3","Tissue RNA - hypothalamus [nTPM]":"161.1","Tissue RNA - kidney [nTPM]":"84.0","Tissue RNA - liver [nTPM]":"31.6","Tissue RNA - lung [nTPM]":"44.6","Tissue RNA - lymph node [nTPM]":"39.2","Tissue RNA - medulla oblongata [nTPM]":"232.3","Tissue RNA - midbrain [nTPM]":"238.4","Tissue RNA - ovary [nTPM]":"30.1","Tissue RNA - pancreas [nTPM]":"22.5","Tissue RNA - parathyroid gland [nTPM]":"51.1","Tissue RNA - pituitary gland [nTPM]":"17.0","Tissue RNA - placenta [nTPM]":"36.0","Tissue RNA - pons [nTPM]":"217.0","Tissue RNA - prostate [nTPM]":"29.7","Tissue RNA - rectum [nTPM]":"24.2","Tissue RNA - retina [nTPM]":"87.4","Tissue RNA - salivary gland [nTPM]":"24.0","Tissue RNA - seminal vesicle [nTPM]":"33.4","Tissue RNA - skeletal muscle [nTPM]":"79.7","Tissue RNA - skin 1 [nTPM]":"52.0","Tissue RNA - small intestine [nTPM]":"17.4","Tissue RNA - smooth muscle [nTPM]":"36.1","Tissue RNA - spinal cord [nTPM]":"225.4","Tissue RNA - spleen [nTPM]":"30.2","Tissue RNA - stomach 1 [nTPM]":"27.6","Tissue RNA - testis [nTPM]":"48.3","Tissue RNA - thalamus [nTPM]":"238.0","Tissue RNA - thymus [nTPM]":"61.3","Tissue RNA - thyroid gland [nTPM]":"27.7","Tissue RNA - tongue [nTPM]":"79.8","Tissue RNA - tonsil [nTPM]":"46.9","Tissue RNA - urinary bladder [nTPM]":"35.8","Tissue RNA - vagina [nTPM]":"43.8","Tissue RNA - white matter [nTPM]":"293.0","Cell RNA - A-431 [nTPM]":"53.9","Cell RNA - A549 [nTPM]":"97.5","Cell RNA - AF22 [nTPM]":"131.8","Cell RNA - AN3-CA [nTPM]":"11.3","Cell RNA - ASC diff [nTPM]":"88.1","Cell RNA - ASC TERT1 [nTPM]":"80.0","Cell RNA - BEWO [nTPM]":"52.2","Cell RNA - BJ [nTPM]":"48.3","Cell RNA - BJ hTERT+ [nTPM]":"61.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"58.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"51.3","Cell RNA - CACO-2 [nTPM]":"59.4","Cell RNA - CAPAN-2 [nTPM]":"55.7","Cell RNA - Daudi [nTPM]":"71.0","Cell RNA - EFO-21 [nTPM]":"16.8","Cell RNA - fHDF\/TERT166 [nTPM]":"107.8","Cell RNA - GAMG [nTPM]":"73.5","Cell RNA - HaCaT [nTPM]":"39.8","Cell RNA - HAP1 [nTPM]":"93.8","Cell RNA - HBEC3-KT [nTPM]":"56.7","Cell RNA - HBF TERT88 [nTPM]":"84.3","Cell RNA - HDLM-2 [nTPM]":"124.7","Cell RNA - HEK 293 [nTPM]":"51.4","Cell RNA - HEL [nTPM]":"169.4","Cell RNA - HeLa [nTPM]":"122.2","Cell RNA - Hep G2 [nTPM]":"46.1","Cell RNA - HHSteC [nTPM]":"66.7","Cell RNA - HL-60 [nTPM]":"86.9","Cell RNA - HMC-1 [nTPM]":"68.2","Cell RNA - HSkMC [nTPM]":"64.0","Cell RNA - hTCEpi [nTPM]":"82.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"97.6","Cell RNA - hTERT-HME1 [nTPM]":"164.4","Cell RNA - hTERT-RPE1 [nTPM]":"61.6","Cell RNA - HUVEC TERT2 [nTPM]":"73.4","Cell RNA - JURKAT [nTPM]":"68.0","Cell RNA - K-562 [nTPM]":"76.4","Cell RNA - Karpas-707 [nTPM]":"158.2","Cell RNA - LHCN-M2 [nTPM]":"77.8","Cell RNA - MCF7 [nTPM]":"54.1","Cell RNA - MOLT-4 [nTPM]":"154.6","Cell RNA - NB-4 [nTPM]":"15.6","Cell RNA - NTERA-2 [nTPM]":"105.8","Cell RNA - OE19 [nTPM]":"47.8","Cell RNA - PC-3 [nTPM]":"24.3","Cell RNA - REH [nTPM]":"78.0","Cell RNA - RH-30 [nTPM]":"138.8","Cell RNA - RPMI-8226 [nTPM]":"20.8","Cell RNA - RPTEC TERT1 [nTPM]":"80.6","Cell RNA - RT4 [nTPM]":"96.8","Cell RNA - SCLC-21H [nTPM]":"35.1","Cell RNA - SH-SY5Y [nTPM]":"40.7","Cell RNA - SiHa [nTPM]":"121.8","Cell RNA - SK-BR-3 [nTPM]":"82.9","Cell RNA - SK-MEL-30 [nTPM]":"33.6","Cell RNA - SuSa [nTPM]":"183.3","Cell RNA - T-47d [nTPM]":"86.8","Cell RNA - THP-1 [nTPM]":"97.2","Cell RNA - TIME [nTPM]":"78.3","Cell RNA - U-138 MG [nTPM]":"67.1","Cell RNA - U-2 OS [nTPM]":"77.3","Cell RNA - U-2197 [nTPM]":"86.2","Cell RNA - U-251 MG [nTPM]":"70.8","Cell RNA - U-266\/70 [nTPM]":"23.8","Cell RNA - U-266\/84 [nTPM]":"43.1","Cell RNA - U-698 [nTPM]":"103.8","Cell RNA - U-87 MG [nTPM]":"59.4","Cell RNA - U-937 [nTPM]":"44.6","Cell RNA - WM-115 [nTPM]":"53.2","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"1.8","Blood RNA - eosinophil [nTPM]":"1.6","Blood RNA - gdT-cell [nTPM]":"1.9","Blood RNA - intermediate monocyte [nTPM]":"2.1","Blood RNA - MAIT T-cell [nTPM]":"1.9","Blood RNA - memory B-cell [nTPM]":"1.7","Blood RNA - memory CD4 T-cell [nTPM]":"1.9","Blood RNA - memory CD8 T-cell [nTPM]":"2.1","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"5.6","Blood RNA - NK-cell [nTPM]":"1.4","Blood RNA - non-classical monocyte [nTPM]":"4.7","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"3.4","Blood RNA - total PBMC [nTPM]":"1.6","Brain RNA - amygdala [nTPM]":"190.8","Brain RNA - basal ganglia [nTPM]":"236.8","Brain RNA - cerebellum [nTPM]":"179.4","Brain RNA - cerebral cortex [nTPM]":"166.1","Brain RNA - hippocampal formation [nTPM]":"132.3","Brain RNA - hypothalamus [nTPM]":"161.1","Brain RNA - medulla oblongata [nTPM]":"232.3","Brain RNA - midbrain [nTPM]":"238.4","Brain RNA - pons [nTPM]":"217.0","Brain RNA - spinal cord [nTPM]":"225.4","Brain RNA - thalamus [nTPM]":"238.0","Brain RNA - white matter [nTPM]":"293.0","Single Cell Type RNA - Adipocytes [nTPM]":"261.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"102.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"141.6","Single Cell Type RNA - Astrocytes [nTPM]":"77.1","Single Cell Type RNA - B-cells [nTPM]":"65.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"112.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"42.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"38.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"85.4","Single Cell Type RNA - Bipolar cells [nTPM]":"87.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"50.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"39.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"241.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"50.1","Single Cell Type RNA - Club cells [nTPM]":"47.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"90.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"150.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"32.5","Single Cell Type RNA - dendritic cells [nTPM]":"83.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"27.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"86.1","Single Cell Type RNA - Ductal cells [nTPM]":"28.0","Single Cell Type RNA - Early spermatids [nTPM]":"29.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"63.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"68.6","Single Cell Type RNA - Endothelial cells [nTPM]":"106.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"58.7","Single Cell Type RNA - Erythroid cells [nTPM]":"304.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"182.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"24.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"32.9","Single Cell Type RNA - Fibroblasts [nTPM]":"58.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"37.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"70.2","Single Cell Type RNA - granulocytes [nTPM]":"52.6","Single Cell Type RNA - Granulosa cells [nTPM]":"46.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"52.5","Single Cell Type RNA - Hepatocytes [nTPM]":"71.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"57.3","Single Cell Type RNA - Horizontal cells [nTPM]":"84.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"165.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.3","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"121.4","Single Cell Type RNA - Langerhans cells [nTPM]":"80.8","Single Cell Type RNA - Late spermatids [nTPM]":"21.2","Single Cell Type RNA - Leydig cells [nTPM]":"61.8","Single Cell Type RNA - Macrophages [nTPM]":"96.7","Single Cell Type RNA - Melanocytes [nTPM]":"37.4","Single Cell Type RNA - Microglial cells [nTPM]":"114.3","Single Cell Type RNA - monocytes [nTPM]":"95.7","Single Cell Type RNA - Muller glia cells [nTPM]":"64.0","Single Cell Type RNA - NK-cells [nTPM]":"61.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"126.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"336.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"41.7","Single Cell Type RNA - Paneth cells [nTPM]":"34.8","Single Cell Type RNA - Peritubular cells [nTPM]":"55.7","Single Cell Type RNA - Plasma cells [nTPM]":"76.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"59.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"21.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"64.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"96.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"69.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"63.8","Single Cell Type RNA - Spermatocytes [nTPM]":"186.5","Single Cell Type RNA - Spermatogonia [nTPM]":"74.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"147.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"136.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"28.5","Single Cell Type RNA - T-cells [nTPM]":"112.9","Single Cell Type RNA - Theca cells [nTPM]":"33.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"25.8","Single Cell Type RNA - Urothelial cells [nTPM]":"55.2"},{"Gene":"WNK4","Gene synonym":["PRKWNK4"],"Ensembl":"ENSG00000126562","Gene description":"WNK lysine deficient protein kinase 4","Uniprot":["Q96J92"],"Chromosome":"17","Position":"42780610-42797066","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"11.0","kidney":"37.6","prostate":"11.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Distal tubular cells":"160.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"fHDF\/TERT166":"32.6","K-562":"36.8","TIME":"34.1","WM-115":"23.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016500"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA016500":"AB_10962984"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.99e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.3","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.7","Tissue RNA - appendix [nTPM]":"1.1","Tissue RNA - basal ganglia [nTPM]":"0.9","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"2.8","Tissue RNA - cerebellum [nTPM]":"0.8","Tissue RNA - cerebral cortex [nTPM]":"3.3","Tissue RNA - cervix [nTPM]":"0.6","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"9.8","Tissue RNA - duodenum [nTPM]":"1.9","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.7","Tissue RNA - esophagus [nTPM]":"8.9","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"1.7","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"37.6","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"1.1","Tissue RNA - midbrain [nTPM]":"0.7","Tissue RNA - ovary [nTPM]":"4.3","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.2","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.7","Tissue RNA - prostate [nTPM]":"11.6","Tissue RNA - rectum [nTPM]":"11.0","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"1.8","Tissue RNA - seminal vesicle [nTPM]":"1.1","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"3.7","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"3.4","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"1.0","Cell RNA - A-431 [nTPM]":"2.1","Cell RNA - A549 [nTPM]":"1.2","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.7","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"4.8","Cell RNA - BJ [nTPM]":"11.9","Cell RNA - BJ hTERT+ [nTPM]":"4.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.3","Cell RNA - CACO-2 [nTPM]":"0.7","Cell RNA - CAPAN-2 [nTPM]":"1.0","Cell RNA - Daudi [nTPM]":"0.6","Cell RNA - EFO-21 [nTPM]":"6.8","Cell RNA - fHDF\/TERT166 [nTPM]":"32.6","Cell RNA - GAMG [nTPM]":"1.2","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"8.6","Cell RNA - HDLM-2 [nTPM]":"0.6","Cell RNA - HEK 293 [nTPM]":"1.8","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"4.7","Cell RNA - HHSteC [nTPM]":"7.4","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.7","Cell RNA - HSkMC [nTPM]":"3.9","Cell RNA - hTCEpi [nTPM]":"1.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.4","Cell RNA - hTERT-HME1 [nTPM]":"2.1","Cell RNA - hTERT-RPE1 [nTPM]":"2.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"36.8","Cell RNA - Karpas-707 [nTPM]":"1.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"1.1","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"2.0","Cell RNA - PC-3 [nTPM]":"8.2","Cell RNA - REH [nTPM]":"0.6","Cell RNA - RH-30 [nTPM]":"1.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"1.7","Cell RNA - SuSa [nTPM]":"4.1","Cell RNA - T-47d [nTPM]":"2.4","Cell RNA - THP-1 [nTPM]":"2.7","Cell RNA - TIME [nTPM]":"34.1","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"3.1","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"6.2","Cell RNA - U-266\/84 [nTPM]":"5.3","Cell RNA - U-698 [nTPM]":"1.2","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"2.1","Cell RNA - WM-115 [nTPM]":"23.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.7","Brain RNA - basal ganglia [nTPM]":"0.9","Brain RNA - cerebellum [nTPM]":"0.8","Brain RNA - cerebral cortex [nTPM]":"3.3","Brain RNA - hippocampal formation [nTPM]":"1.7","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"1.1","Brain RNA - midbrain [nTPM]":"0.7","Brain RNA - pons [nTPM]":"0.7","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"1.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"160.4","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.7","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"40.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"3.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"WRN","Gene synonym":["RECQ3","RECQL2"],"Ensembl":"ENSG00000165392","Gene description":"WRN RecQ like helicase","Uniprot":["Q14191"],"Chromosome":"8","Position":"31033788-31176138","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["DNA-binding","Exonuclease","Helicase","Hydrolase","Multifunctional enzyme","Nuclease"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"74.7","Early spermatids":"116.3","Oligodendrocytes":"88.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028661"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA028661":"AB_10602255"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.0","Tissue RNA - adrenal gland [nTPM]":"3.6","Tissue RNA - amygdala [nTPM]":"1.7","Tissue RNA - appendix [nTPM]":"3.2","Tissue RNA - basal ganglia [nTPM]":"1.7","Tissue RNA - bone marrow [nTPM]":"8.2","Tissue RNA - breast [nTPM]":"4.8","Tissue RNA - cerebellum [nTPM]":"4.1","Tissue RNA - cerebral cortex [nTPM]":"2.4","Tissue RNA - cervix [nTPM]":"3.0","Tissue RNA - choroid plexus [nTPM]":"2.6","Tissue RNA - colon [nTPM]":"3.5","Tissue RNA - duodenum [nTPM]":"1.5","Tissue RNA - endometrium 1 [nTPM]":"6.4","Tissue RNA - epididymis [nTPM]":"3.2","Tissue RNA - esophagus [nTPM]":"2.7","Tissue RNA - fallopian tube [nTPM]":"2.9","Tissue RNA - gallbladder [nTPM]":"2.4","Tissue RNA - heart muscle [nTPM]":"1.7","Tissue RNA - hippocampal formation [nTPM]":"1.6","Tissue RNA - hypothalamus [nTPM]":"1.7","Tissue RNA - kidney [nTPM]":"2.1","Tissue RNA - liver [nTPM]":"2.5","Tissue RNA - lung [nTPM]":"2.4","Tissue RNA - lymph node [nTPM]":"2.5","Tissue RNA - medulla oblongata [nTPM]":"1.8","Tissue RNA - midbrain [nTPM]":"2.1","Tissue RNA - ovary [nTPM]":"5.2","Tissue RNA - pancreas [nTPM]":"2.6","Tissue RNA - parathyroid gland [nTPM]":"2.0","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"3.6","Tissue RNA - pons [nTPM]":"1.8","Tissue RNA - prostate [nTPM]":"3.5","Tissue RNA - rectum [nTPM]":"2.9","Tissue RNA - retina [nTPM]":"4.4","Tissue RNA - salivary gland [nTPM]":"3.5","Tissue RNA - seminal vesicle [nTPM]":"2.6","Tissue RNA - skeletal muscle [nTPM]":"2.1","Tissue RNA - skin 1 [nTPM]":"4.1","Tissue RNA - small intestine [nTPM]":"2.5","Tissue RNA - smooth muscle [nTPM]":"4.2","Tissue RNA - spinal cord [nTPM]":"1.2","Tissue RNA - spleen [nTPM]":"3.1","Tissue RNA - stomach 1 [nTPM]":"2.3","Tissue RNA - testis [nTPM]":"3.0","Tissue RNA - thalamus [nTPM]":"1.9","Tissue RNA - thymus [nTPM]":"3.2","Tissue RNA - thyroid gland [nTPM]":"3.2","Tissue RNA - tongue [nTPM]":"2.2","Tissue RNA - tonsil [nTPM]":"3.0","Tissue RNA - urinary bladder [nTPM]":"2.6","Tissue RNA - vagina [nTPM]":"2.3","Tissue RNA - white matter [nTPM]":"3.1","Cell RNA - A-431 [nTPM]":"4.4","Cell RNA - A549 [nTPM]":"5.9","Cell RNA - AF22 [nTPM]":"10.8","Cell RNA - AN3-CA [nTPM]":"5.3","Cell RNA - ASC diff [nTPM]":"6.7","Cell RNA - ASC TERT1 [nTPM]":"9.8","Cell RNA - BEWO [nTPM]":"5.0","Cell RNA - BJ [nTPM]":"4.7","Cell RNA - BJ hTERT+ [nTPM]":"4.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.6","Cell RNA - CACO-2 [nTPM]":"2.7","Cell RNA - CAPAN-2 [nTPM]":"1.5","Cell RNA - Daudi [nTPM]":"10.0","Cell RNA - EFO-21 [nTPM]":"4.6","Cell RNA - fHDF\/TERT166 [nTPM]":"4.3","Cell RNA - GAMG [nTPM]":"4.4","Cell RNA - HaCaT [nTPM]":"2.4","Cell RNA - HAP1 [nTPM]":"6.4","Cell RNA - HBEC3-KT [nTPM]":"3.8","Cell RNA - HBF TERT88 [nTPM]":"9.7","Cell RNA - HDLM-2 [nTPM]":"3.3","Cell RNA - HEK 293 [nTPM]":"4.3","Cell RNA - HEL [nTPM]":"9.6","Cell RNA - HeLa [nTPM]":"4.9","Cell RNA - Hep G2 [nTPM]":"4.4","Cell RNA - HHSteC [nTPM]":"5.4","Cell RNA - HL-60 [nTPM]":"8.7","Cell RNA - HMC-1 [nTPM]":"4.3","Cell RNA - HSkMC [nTPM]":"7.1","Cell RNA - hTCEpi [nTPM]":"3.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.6","Cell RNA - hTERT-HME1 [nTPM]":"6.2","Cell RNA - hTERT-RPE1 [nTPM]":"3.9","Cell RNA - HUVEC TERT2 [nTPM]":"7.7","Cell RNA - JURKAT [nTPM]":"6.1","Cell RNA - K-562 [nTPM]":"14.5","Cell RNA - Karpas-707 [nTPM]":"5.0","Cell RNA - LHCN-M2 [nTPM]":"6.8","Cell RNA - MCF7 [nTPM]":"2.0","Cell RNA - MOLT-4 [nTPM]":"17.5","Cell RNA - NB-4 [nTPM]":"6.6","Cell RNA - NTERA-2 [nTPM]":"7.7","Cell RNA - OE19 [nTPM]":"5.1","Cell RNA - PC-3 [nTPM]":"3.2","Cell RNA - REH [nTPM]":"7.5","Cell RNA - RH-30 [nTPM]":"7.5","Cell RNA - RPMI-8226 [nTPM]":"6.7","Cell RNA - RPTEC TERT1 [nTPM]":"2.9","Cell RNA - RT4 [nTPM]":"4.4","Cell RNA - SCLC-21H [nTPM]":"3.3","Cell RNA - SH-SY5Y [nTPM]":"5.2","Cell RNA - SiHa [nTPM]":"6.9","Cell RNA - SK-BR-3 [nTPM]":"2.7","Cell RNA - SK-MEL-30 [nTPM]":"3.8","Cell RNA - SuSa [nTPM]":"4.9","Cell RNA - T-47d [nTPM]":"2.9","Cell RNA - THP-1 [nTPM]":"5.3","Cell RNA - TIME [nTPM]":"9.1","Cell RNA - U-138 MG [nTPM]":"6.2","Cell RNA - U-2 OS [nTPM]":"3.8","Cell RNA - U-2197 [nTPM]":"3.1","Cell RNA - U-251 MG [nTPM]":"4.9","Cell RNA - U-266\/70 [nTPM]":"1.4","Cell RNA - U-266\/84 [nTPM]":"3.0","Cell RNA - U-698 [nTPM]":"14.6","Cell RNA - U-87 MG [nTPM]":"5.5","Cell RNA - U-937 [nTPM]":"3.8","Cell RNA - WM-115 [nTPM]":"4.2","Blood RNA - basophil [nTPM]":"0.8","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"1.7","Brain RNA - basal ganglia [nTPM]":"1.7","Brain RNA - cerebellum [nTPM]":"4.1","Brain RNA - cerebral cortex [nTPM]":"2.4","Brain RNA - hippocampal formation [nTPM]":"1.6","Brain RNA - hypothalamus [nTPM]":"1.7","Brain RNA - medulla oblongata [nTPM]":"1.8","Brain RNA - midbrain [nTPM]":"2.1","Brain RNA - pons [nTPM]":"1.8","Brain RNA - spinal cord [nTPM]":"1.2","Brain RNA - thalamus [nTPM]":"1.9","Brain RNA - white matter [nTPM]":"3.1","Single Cell Type RNA - Adipocytes [nTPM]":"17.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.6","Single Cell Type RNA - Astrocytes [nTPM]":"74.7","Single Cell Type RNA - B-cells [nTPM]":"15.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Bipolar cells [nTPM]":"14.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"8.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.1","Single Cell Type RNA - dendritic cells [nTPM]":"18.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.7","Single Cell Type RNA - Early spermatids [nTPM]":"116.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"32.3","Single Cell Type RNA - Endothelial cells [nTPM]":"12.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"49.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"59.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.7","Single Cell Type RNA - Fibroblasts [nTPM]":"15.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.1","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"18.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.1","Single Cell Type RNA - Hepatocytes [nTPM]":"9.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.3","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"54.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.8","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.3","Single Cell Type RNA - Langerhans cells [nTPM]":"6.6","Single Cell Type RNA - Late spermatids [nTPM]":"12.8","Single Cell Type RNA - Leydig cells [nTPM]":"19.0","Single Cell Type RNA - Macrophages [nTPM]":"7.8","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"51.5","Single Cell Type RNA - monocytes [nTPM]":"6.9","Single Cell Type RNA - Muller glia cells [nTPM]":"14.3","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"61.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"88.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.1","Single Cell Type RNA - Paneth cells [nTPM]":"4.2","Single Cell Type RNA - Peritubular cells [nTPM]":"14.3","Single Cell Type RNA - Plasma cells [nTPM]":"16.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.3","Single Cell Type RNA - Spermatocytes [nTPM]":"10.9","Single Cell Type RNA - Spermatogonia [nTPM]":"19.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.6","Single Cell Type RNA - T-cells [nTPM]":"13.0","Single Cell Type RNA - Theca cells [nTPM]":"15.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.7","Single Cell Type RNA - Urothelial cells [nTPM]":"11.0"},{"Gene":"XK","Gene synonym":["Kx","NA","NAC","X1k","XKR1"],"Ensembl":"ENSG00000047597","Gene description":"X-linked Kx blood group","Uniprot":["P51811"],"Chromosome":"X","Position":"37685791-37732130","Protein class":["Blood group antigen proteins","Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Transport"],"Molecular function":["Blood group antigen"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"14.2","intestine":"12.2","stomach 1":"11.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"26.7","Erythroid cells":"63.5","Gastric mucus-secreting cells":"17.9","Proximal enterocytes":"21.5","Undifferentiated cells":"14.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"6.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"53","RNA blood cell specific nTPM":{"basophil":"10.2","eosinophil":"5.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"102","RNA blood lineage specific nTPM":{"granulocytes":"10.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"44.4","HL-60":"23.2","K-562":"29.1","NB-4":"21.1","RPMI-8226":"20.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019036"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm","Vesicles"],"Antibody RRID":{"HPA019036":"AB_1846286"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.13e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"2.1","Tissue RNA - amygdala [nTPM]":"2.5","Tissue RNA - appendix [nTPM]":"1.4","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"14.2","Tissue RNA - breast [nTPM]":"0.7","Tissue RNA - cerebellum [nTPM]":"2.3","Tissue RNA - cerebral cortex [nTPM]":"3.0","Tissue RNA - cervix [nTPM]":"1.2","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"12.2","Tissue RNA - duodenum [nTPM]":"10.8","Tissue RNA - endometrium 1 [nTPM]":"0.7","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"2.0","Tissue RNA - fallopian tube [nTPM]":"3.8","Tissue RNA - gallbladder [nTPM]":"0.9","Tissue RNA - heart muscle [nTPM]":"4.3","Tissue RNA - hippocampal formation [nTPM]":"3.2","Tissue RNA - hypothalamus [nTPM]":"4.9","Tissue RNA - kidney [nTPM]":"0.9","Tissue RNA - liver [nTPM]":"0.8","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"1.6","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"0.7","Tissue RNA - pancreas [nTPM]":"4.9","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"1.3","Tissue RNA - placenta [nTPM]":"0.7","Tissue RNA - pons [nTPM]":"2.0","Tissue RNA - prostate [nTPM]":"1.5","Tissue RNA - rectum [nTPM]":"11.2","Tissue RNA - retina [nTPM]":"2.1","Tissue RNA - salivary gland [nTPM]":"1.2","Tissue RNA - seminal vesicle [nTPM]":"0.9","Tissue RNA - skeletal muscle [nTPM]":"5.4","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"10.6","Tissue RNA - smooth muscle [nTPM]":"1.8","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"11.5","Tissue RNA - testis [nTPM]":"1.4","Tissue RNA - thalamus [nTPM]":"2.8","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.9","Tissue RNA - tongue [nTPM]":"5.8","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"1.1","Tissue RNA - vagina [nTPM]":"0.8","Tissue RNA - white matter [nTPM]":"1.4","Cell RNA - A-431 [nTPM]":"17.4","Cell RNA - A549 [nTPM]":"1.7","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"15.9","Cell RNA - Daudi [nTPM]":"14.7","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.8","Cell RNA - HaCaT [nTPM]":"2.7","Cell RNA - HAP1 [nTPM]":"15.4","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"4.2","Cell RNA - HEL [nTPM]":"44.4","Cell RNA - HeLa [nTPM]":"2.4","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"23.2","Cell RNA - HMC-1 [nTPM]":"3.5","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"29.1","Cell RNA - Karpas-707 [nTPM]":"10.9","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"1.7","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"21.1","Cell RNA - NTERA-2 [nTPM]":"5.5","Cell RNA - OE19 [nTPM]":"0.7","Cell RNA - PC-3 [nTPM]":"5.6","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"20.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"1.1","Cell RNA - SCLC-21H [nTPM]":"4.1","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.8","Cell RNA - SK-BR-3 [nTPM]":"1.4","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.9","Cell RNA - T-47d [nTPM]":"2.1","Cell RNA - THP-1 [nTPM]":"5.6","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"2.4","Cell RNA - U-266\/70 [nTPM]":"9.3","Cell RNA - U-266\/84 [nTPM]":"16.5","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"12.1","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"10.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"5.8","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"2.5","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"2.3","Brain RNA - cerebral cortex [nTPM]":"3.0","Brain RNA - hippocampal formation [nTPM]":"3.2","Brain RNA - hypothalamus [nTPM]":"4.9","Brain RNA - medulla oblongata [nTPM]":"1.6","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"2.0","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"2.8","Brain RNA - white matter [nTPM]":"1.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"0.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"26.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.1","Single Cell Type RNA - Erythroid cells [nTPM]":"63.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.9","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.1","Single Cell Type RNA - Paneth cells [nTPM]":"9.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"2.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"21.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.3","Single Cell Type RNA - Spermatocytes [nTPM]":"10.2","Single Cell Type RNA - Spermatogonia [nTPM]":"6.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.7","Single Cell Type RNA - Urothelial cells [nTPM]":"1.5"},{"Gene":"XPNPEP2","Gene synonym":[],"Ensembl":"ENSG00000122121","Gene description":"X-prolyl aminopeptidase 2","Uniprot":["O43895"],"Chromosome":"X","Position":"129738949-129769536","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Aminopeptidase","Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"intestine":"166.6","kidney":"156.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Proximal enterocytes":"475.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"18.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"gdT-cell":"4.3","intermediate monocyte":"1.4","MAIT T-cell":"1.2","memory CD4 T-cell":"1.3","memory CD8 T-cell":"2.8","naive CD8 T-cell":"2.0","non-classical monocyte":"2.8","T-reg":"1.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"monocytes":"2.8","T-cells":"4.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"8.2","ASC TERT1":"40.1","HSkMC":"21.1"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000339","CAB025136","CAB025269","HPA064568"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"13000000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB025136":null,"CAB025269":null,"HPA000339":"AB_1858894","HPA064568":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-3"},"Tissue RNA - adipose tissue [nTPM]":"7.5","Tissue RNA - adrenal gland [nTPM]":"0.9","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"3.7","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"3.0","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"3.7","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"5.5","Tissue RNA - duodenum [nTPM]":"99.0","Tissue RNA - endometrium 1 [nTPM]":"2.4","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"2.2","Tissue RNA - fallopian tube [nTPM]":"6.3","Tissue RNA - gallbladder [nTPM]":"4.3","Tissue RNA - heart muscle [nTPM]":"5.3","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"156.0","Tissue RNA - liver [nTPM]":"23.1","Tissue RNA - lung [nTPM]":"2.1","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"1.8","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"1.2","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"1.8","Tissue RNA - rectum [nTPM]":"6.3","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"1.5","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"4.4","Tissue RNA - small intestine [nTPM]":"166.6","Tissue RNA - smooth muscle [nTPM]":"6.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"3.4","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"1.4","Tissue RNA - tongue [nTPM]":"2.4","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"7.8","Tissue RNA - vagina [nTPM]":"4.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"8.2","Cell RNA - ASC TERT1 [nTPM]":"40.1","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"1.3","Cell RNA - HHSteC [nTPM]":"1.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"21.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"1.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.7","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"1.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"1.5","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"4.3","Blood RNA - intermediate monocyte [nTPM]":"1.4","Blood RNA - MAIT T-cell [nTPM]":"1.2","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"2.8","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"2.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"2.8","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"1.4","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"1.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"10.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"18.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"3.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"21.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"475.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"75.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.4","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"XPNPEP3","Gene synonym":["APP3","ICP55","NPHPL1"],"Ensembl":"ENSG00000196236","Gene description":"X-prolyl aminopeptidase 3","Uniprot":["Q9NQH7"],"Chromosome":"22","Position":"40857077-40932815","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Aminopeptidase","Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant","Nephronophthisis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"232.9","Late spermatids":"306.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000527"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA000527":"AB_1079266"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.19e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.00e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.10e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Tissue RNA - adipose tissue [nTPM]":"2.7","Tissue RNA - adrenal gland [nTPM]":"4.9","Tissue RNA - amygdala [nTPM]":"6.4","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"6.3","Tissue RNA - bone marrow [nTPM]":"1.6","Tissue RNA - breast [nTPM]":"2.6","Tissue RNA - cerebellum [nTPM]":"8.3","Tissue RNA - cerebral cortex [nTPM]":"7.8","Tissue RNA - cervix [nTPM]":"2.9","Tissue RNA - choroid plexus [nTPM]":"7.1","Tissue RNA - colon [nTPM]":"2.5","Tissue RNA - duodenum [nTPM]":"14.6","Tissue RNA - endometrium 1 [nTPM]":"4.7","Tissue RNA - epididymis [nTPM]":"5.0","Tissue RNA - esophagus [nTPM]":"2.8","Tissue RNA - fallopian tube [nTPM]":"3.7","Tissue RNA - gallbladder [nTPM]":"4.4","Tissue RNA - heart muscle [nTPM]":"5.3","Tissue RNA - hippocampal formation [nTPM]":"7.8","Tissue RNA - hypothalamus [nTPM]":"6.1","Tissue RNA - kidney [nTPM]":"3.7","Tissue RNA - liver [nTPM]":"8.2","Tissue RNA - lung [nTPM]":"2.4","Tissue RNA - lymph node [nTPM]":"2.5","Tissue RNA - medulla oblongata [nTPM]":"7.2","Tissue RNA - midbrain [nTPM]":"6.6","Tissue RNA - ovary [nTPM]":"3.8","Tissue RNA - pancreas [nTPM]":"3.6","Tissue RNA - parathyroid gland [nTPM]":"2.1","Tissue RNA - pituitary gland [nTPM]":"3.7","Tissue RNA - placenta [nTPM]":"1.5","Tissue RNA - pons [nTPM]":"6.6","Tissue RNA - prostate [nTPM]":"2.8","Tissue RNA - rectum [nTPM]":"2.2","Tissue RNA - retina [nTPM]":"4.4","Tissue RNA - salivary gland [nTPM]":"3.4","Tissue RNA - seminal vesicle [nTPM]":"2.5","Tissue RNA - skeletal muscle [nTPM]":"5.5","Tissue RNA - skin 1 [nTPM]":"5.5","Tissue RNA - small intestine [nTPM]":"10.1","Tissue RNA - smooth muscle [nTPM]":"2.4","Tissue RNA - spinal cord [nTPM]":"5.6","Tissue RNA - spleen [nTPM]":"2.8","Tissue RNA - stomach 1 [nTPM]":"2.8","Tissue RNA - testis [nTPM]":"3.7","Tissue RNA - thalamus [nTPM]":"6.7","Tissue RNA - thymus [nTPM]":"5.9","Tissue RNA - thyroid gland [nTPM]":"3.2","Tissue RNA - tongue [nTPM]":"3.5","Tissue RNA - tonsil [nTPM]":"1.9","Tissue RNA - urinary bladder [nTPM]":"3.7","Tissue RNA - vagina [nTPM]":"2.8","Tissue RNA - white matter [nTPM]":"9.0","Cell RNA - A-431 [nTPM]":"2.7","Cell RNA - A549 [nTPM]":"4.1","Cell RNA - AF22 [nTPM]":"2.5","Cell RNA - AN3-CA [nTPM]":"5.5","Cell RNA - ASC diff [nTPM]":"6.3","Cell RNA - ASC TERT1 [nTPM]":"4.6","Cell RNA - BEWO [nTPM]":"2.1","Cell RNA - BJ [nTPM]":"3.3","Cell RNA - BJ hTERT+ [nTPM]":"2.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.7","Cell RNA - CACO-2 [nTPM]":"3.1","Cell RNA - CAPAN-2 [nTPM]":"1.6","Cell RNA - Daudi [nTPM]":"5.2","Cell RNA - EFO-21 [nTPM]":"1.8","Cell RNA - fHDF\/TERT166 [nTPM]":"6.5","Cell RNA - GAMG [nTPM]":"7.8","Cell RNA - HaCaT [nTPM]":"7.3","Cell RNA - HAP1 [nTPM]":"4.7","Cell RNA - HBEC3-KT [nTPM]":"2.4","Cell RNA - HBF TERT88 [nTPM]":"2.7","Cell RNA - HDLM-2 [nTPM]":"3.5","Cell RNA - HEK 293 [nTPM]":"9.7","Cell RNA - HEL [nTPM]":"3.3","Cell RNA - HeLa [nTPM]":"9.7","Cell RNA - Hep G2 [nTPM]":"7.5","Cell RNA - HHSteC [nTPM]":"3.2","Cell RNA - HL-60 [nTPM]":"6.0","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"4.0","Cell RNA - hTCEpi [nTPM]":"3.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.7","Cell RNA - hTERT-HME1 [nTPM]":"3.3","Cell RNA - hTERT-RPE1 [nTPM]":"2.7","Cell RNA - HUVEC TERT2 [nTPM]":"3.3","Cell RNA - JURKAT [nTPM]":"3.8","Cell RNA - K-562 [nTPM]":"2.9","Cell RNA - Karpas-707 [nTPM]":"4.8","Cell RNA - LHCN-M2 [nTPM]":"4.3","Cell RNA - MCF7 [nTPM]":"4.1","Cell RNA - MOLT-4 [nTPM]":"3.1","Cell RNA - NB-4 [nTPM]":"3.2","Cell RNA - NTERA-2 [nTPM]":"1.5","Cell RNA - OE19 [nTPM]":"5.0","Cell RNA - PC-3 [nTPM]":"8.3","Cell RNA - REH [nTPM]":"3.9","Cell RNA - RH-30 [nTPM]":"3.3","Cell RNA - RPMI-8226 [nTPM]":"3.0","Cell RNA - RPTEC TERT1 [nTPM]":"5.9","Cell RNA - RT4 [nTPM]":"3.6","Cell RNA - SCLC-21H [nTPM]":"2.3","Cell RNA - SH-SY5Y [nTPM]":"1.9","Cell RNA - SiHa [nTPM]":"3.9","Cell RNA - SK-BR-3 [nTPM]":"4.8","Cell RNA - SK-MEL-30 [nTPM]":"3.3","Cell RNA - SuSa [nTPM]":"2.6","Cell RNA - T-47d [nTPM]":"6.1","Cell RNA - THP-1 [nTPM]":"2.7","Cell RNA - TIME [nTPM]":"3.2","Cell RNA - U-138 MG [nTPM]":"3.6","Cell RNA - U-2 OS [nTPM]":"3.4","Cell RNA - U-2197 [nTPM]":"3.4","Cell RNA - U-251 MG [nTPM]":"2.1","Cell RNA - U-266\/70 [nTPM]":"4.7","Cell RNA - U-266\/84 [nTPM]":"4.0","Cell RNA - U-698 [nTPM]":"7.4","Cell RNA - U-87 MG [nTPM]":"5.6","Cell RNA - U-937 [nTPM]":"8.5","Cell RNA - WM-115 [nTPM]":"2.5","Blood RNA - basophil [nTPM]":"2.8","Blood RNA - classical monocyte [nTPM]":"2.5","Blood RNA - eosinophil [nTPM]":"2.9","Blood RNA - gdT-cell [nTPM]":"2.1","Blood RNA - intermediate monocyte [nTPM]":"2.5","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"3.7","Blood RNA - memory CD4 T-cell [nTPM]":"1.2","Blood RNA - memory CD8 T-cell [nTPM]":"1.2","Blood RNA - myeloid DC [nTPM]":"1.9","Blood RNA - naive B-cell [nTPM]":"1.9","Blood RNA - naive CD4 T-cell [nTPM]":"2.4","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"3.6","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"6.9","Blood RNA - plasmacytoid DC [nTPM]":"3.8","Blood RNA - T-reg [nTPM]":"1.9","Blood RNA - total PBMC [nTPM]":"2.8","Brain RNA - amygdala [nTPM]":"6.4","Brain RNA - basal ganglia [nTPM]":"6.3","Brain RNA - cerebellum [nTPM]":"8.3","Brain RNA - cerebral cortex [nTPM]":"7.8","Brain RNA - hippocampal formation [nTPM]":"7.8","Brain RNA - hypothalamus [nTPM]":"6.1","Brain RNA - medulla oblongata [nTPM]":"7.2","Brain RNA - midbrain [nTPM]":"6.6","Brain RNA - pons [nTPM]":"6.6","Brain RNA - spinal cord [nTPM]":"5.6","Brain RNA - thalamus [nTPM]":"6.7","Brain RNA - white matter [nTPM]":"9.0","Single Cell Type RNA - Adipocytes [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.6","Single Cell Type RNA - Astrocytes [nTPM]":"32.0","Single Cell Type RNA - B-cells [nTPM]":"12.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"16.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"22.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"14.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"21.7","Single Cell Type RNA - dendritic cells [nTPM]":"11.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"12.2","Single Cell Type RNA - Early spermatids [nTPM]":"232.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"37.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.6","Single Cell Type RNA - Endothelial cells [nTPM]":"11.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.8","Single Cell Type RNA - Erythroid cells [nTPM]":"12.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.7","Single Cell Type RNA - Fibroblasts [nTPM]":"13.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.0","Single Cell Type RNA - granulocytes [nTPM]":"14.0","Single Cell Type RNA - Granulosa cells [nTPM]":"17.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.8","Single Cell Type RNA - Hepatocytes [nTPM]":"36.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.7","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.5","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"12.6","Single Cell Type RNA - Langerhans cells [nTPM]":"15.7","Single Cell Type RNA - Late spermatids [nTPM]":"306.8","Single Cell Type RNA - Leydig cells [nTPM]":"19.9","Single Cell Type RNA - Macrophages [nTPM]":"11.9","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"7.8","Single Cell Type RNA - Muller glia cells [nTPM]":"13.0","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"42.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.4","Single Cell Type RNA - Paneth cells [nTPM]":"9.5","Single Cell Type RNA - Peritubular cells [nTPM]":"15.4","Single Cell Type RNA - Plasma cells [nTPM]":"11.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"25.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"38.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.8","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.7","Single Cell Type RNA - Spermatocytes [nTPM]":"65.6","Single Cell Type RNA - Spermatogonia [nTPM]":"34.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.0","Single Cell Type RNA - T-cells [nTPM]":"11.0","Single Cell Type RNA - Theca cells [nTPM]":"19.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.7","Single Cell Type RNA - Urothelial cells [nTPM]":"7.6"},{"Gene":"XYLT1","Gene synonym":["PXYLT1","XT-I"],"Ensembl":"ENSG00000103489","Gene description":"Xylosyltransferase 1","Uniprot":["Q86Y38"],"Chromosome":"16","Position":"17101769-17470960","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"1194.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"2.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"monocytes":"2.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"55.1","ASC TERT1":"34.0","U-2197":"57.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007478","HPA007966"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Plasma membrane"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"150000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"HPA007478":"AB_1080616","HPA007966":"AB_1080618"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.4","Tissue RNA - adrenal gland [nTPM]":"6.2","Tissue RNA - amygdala [nTPM]":"6.2","Tissue RNA - appendix [nTPM]":"4.9","Tissue RNA - basal ganglia [nTPM]":"8.0","Tissue RNA - bone marrow [nTPM]":"7.2","Tissue RNA - breast [nTPM]":"4.5","Tissue RNA - cerebellum [nTPM]":"2.3","Tissue RNA - cerebral cortex [nTPM]":"6.3","Tissue RNA - cervix [nTPM]":"7.8","Tissue RNA - choroid plexus [nTPM]":"8.5","Tissue RNA - colon [nTPM]":"8.8","Tissue RNA - duodenum [nTPM]":"4.3","Tissue RNA - endometrium 1 [nTPM]":"7.9","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"5.1","Tissue RNA - fallopian tube [nTPM]":"3.7","Tissue RNA - gallbladder [nTPM]":"2.3","Tissue RNA - heart muscle [nTPM]":"4.2","Tissue RNA - hippocampal formation [nTPM]":"8.8","Tissue RNA - hypothalamus [nTPM]":"3.6","Tissue RNA - kidney [nTPM]":"1.0","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"3.5","Tissue RNA - lymph node [nTPM]":"5.1","Tissue RNA - medulla oblongata [nTPM]":"3.7","Tissue RNA - midbrain [nTPM]":"4.3","Tissue RNA - ovary [nTPM]":"5.3","Tissue RNA - pancreas [nTPM]":"2.8","Tissue RNA - parathyroid gland [nTPM]":"0.9","Tissue RNA - pituitary gland [nTPM]":"0.6","Tissue RNA - placenta [nTPM]":"6.0","Tissue RNA - pons [nTPM]":"4.2","Tissue RNA - prostate [nTPM]":"2.7","Tissue RNA - rectum [nTPM]":"5.2","Tissue RNA - retina [nTPM]":"8.3","Tissue RNA - salivary gland [nTPM]":"2.5","Tissue RNA - seminal vesicle [nTPM]":"4.5","Tissue RNA - skeletal muscle [nTPM]":"1.1","Tissue RNA - skin 1 [nTPM]":"5.0","Tissue RNA - small intestine [nTPM]":"5.3","Tissue RNA - smooth muscle [nTPM]":"5.7","Tissue RNA - spinal cord [nTPM]":"1.6","Tissue RNA - spleen [nTPM]":"5.4","Tissue RNA - stomach 1 [nTPM]":"3.4","Tissue RNA - testis [nTPM]":"2.3","Tissue RNA - thalamus [nTPM]":"3.6","Tissue RNA - thymus [nTPM]":"4.1","Tissue RNA - thyroid gland [nTPM]":"2.2","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"4.3","Tissue RNA - urinary bladder [nTPM]":"4.3","Tissue RNA - vagina [nTPM]":"4.6","Tissue RNA - white matter [nTPM]":"4.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"8.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"55.1","Cell RNA - ASC TERT1 [nTPM]":"34.0","Cell RNA - BEWO [nTPM]":"9.6","Cell RNA - BJ [nTPM]":"25.6","Cell RNA - BJ hTERT+ [nTPM]":"12.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.0","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.6","Cell RNA - Daudi [nTPM]":"6.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"31.3","Cell RNA - GAMG [nTPM]":"0.9","Cell RNA - HaCaT [nTPM]":"0.6","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"5.1","Cell RNA - HBF TERT88 [nTPM]":"4.5","Cell RNA - HDLM-2 [nTPM]":"12.1","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"8.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.6","Cell RNA - HL-60 [nTPM]":"11.5","Cell RNA - HMC-1 [nTPM]":"10.2","Cell RNA - HSkMC [nTPM]":"12.6","Cell RNA - hTCEpi [nTPM]":"0.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.0","Cell RNA - hTERT-HME1 [nTPM]":"2.4","Cell RNA - hTERT-RPE1 [nTPM]":"4.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"23.8","Cell RNA - LHCN-M2 [nTPM]":"2.8","Cell RNA - MCF7 [nTPM]":"0.8","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"12.4","Cell RNA - NTERA-2 [nTPM]":"8.5","Cell RNA - OE19 [nTPM]":"4.4","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"3.5","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"11.5","Cell RNA - SCLC-21H [nTPM]":"2.0","Cell RNA - SH-SY5Y [nTPM]":"15.2","Cell RNA - SiHa [nTPM]":"1.9","Cell RNA - SK-BR-3 [nTPM]":"7.9","Cell RNA - SK-MEL-30 [nTPM]":"1.4","Cell RNA - SuSa [nTPM]":"5.9","Cell RNA - T-47d [nTPM]":"1.9","Cell RNA - THP-1 [nTPM]":"7.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"24.6","Cell RNA - U-2 OS [nTPM]":"2.9","Cell RNA - U-2197 [nTPM]":"57.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"26.4","Cell RNA - U-266\/84 [nTPM]":"1.4","Cell RNA - U-698 [nTPM]":"11.6","Cell RNA - U-87 MG [nTPM]":"28.9","Cell RNA - U-937 [nTPM]":"12.8","Cell RNA - WM-115 [nTPM]":"22.4","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"2.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"6.2","Brain RNA - basal ganglia [nTPM]":"8.0","Brain RNA - cerebellum [nTPM]":"2.3","Brain RNA - cerebral cortex [nTPM]":"6.3","Brain RNA - hippocampal formation [nTPM]":"8.8","Brain RNA - hypothalamus [nTPM]":"3.6","Brain RNA - medulla oblongata [nTPM]":"3.7","Brain RNA - midbrain [nTPM]":"4.3","Brain RNA - pons [nTPM]":"4.2","Brain RNA - spinal cord [nTPM]":"1.6","Brain RNA - thalamus [nTPM]":"3.6","Brain RNA - white matter [nTPM]":"4.6","Single Cell Type RNA - Adipocytes [nTPM]":"1.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.5","Single Cell Type RNA - Astrocytes [nTPM]":"45.4","Single Cell Type RNA - B-cells [nTPM]":"9.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"12.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"98.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.7","Single Cell Type RNA - dendritic cells [nTPM]":"12.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"24.7","Single Cell Type RNA - Endothelial cells [nTPM]":"2.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.6","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"172.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.1","Single Cell Type RNA - Fibroblasts [nTPM]":"12.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.8","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"6.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"72.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.3","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"9.7","Single Cell Type RNA - Langerhans cells [nTPM]":"27.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"12.8","Single Cell Type RNA - Macrophages [nTPM]":"8.5","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"29.0","Single Cell Type RNA - monocytes [nTPM]":"6.1","Single Cell Type RNA - Muller glia cells [nTPM]":"1.9","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1194.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"63.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.0","Single Cell Type RNA - Paneth cells [nTPM]":"7.4","Single Cell Type RNA - Peritubular cells [nTPM]":"50.0","Single Cell Type RNA - Plasma cells [nTPM]":"6.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"13.1","Single Cell Type RNA - T-cells [nTPM]":"7.7","Single Cell Type RNA - Theca cells [nTPM]":"8.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.9","Single Cell Type RNA - Urothelial cells [nTPM]":"6.4"},{"Gene":"XYLT2","Gene synonym":["PXYLT2","XT-II"],"Ensembl":"ENSG00000015532","Gene description":"Xylosyltransferase 2","Uniprot":["Q9H1B5"],"Chromosome":"17","Position":"50346126-50363138","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"stomach 1":"86.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Early spermatids":"316.4","Late spermatids":"91.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1100000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 4: Stomach - Digestion","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.4","Tissue RNA - adrenal gland [nTPM]":"9.7","Tissue RNA - amygdala [nTPM]":"4.9","Tissue RNA - appendix [nTPM]":"6.6","Tissue RNA - basal ganglia [nTPM]":"5.2","Tissue RNA - bone marrow [nTPM]":"4.5","Tissue RNA - breast [nTPM]":"8.1","Tissue RNA - cerebellum [nTPM]":"8.0","Tissue RNA - cerebral cortex [nTPM]":"8.2","Tissue RNA - cervix [nTPM]":"12.3","Tissue RNA - choroid plexus [nTPM]":"8.7","Tissue RNA - colon [nTPM]":"10.0","Tissue RNA - duodenum [nTPM]":"9.6","Tissue RNA - endometrium 1 [nTPM]":"11.4","Tissue RNA - epididymis [nTPM]":"5.3","Tissue RNA - esophagus [nTPM]":"8.4","Tissue RNA - fallopian tube [nTPM]":"11.8","Tissue RNA - gallbladder [nTPM]":"6.6","Tissue RNA - heart muscle [nTPM]":"9.1","Tissue RNA - hippocampal formation [nTPM]":"5.6","Tissue RNA - hypothalamus [nTPM]":"3.0","Tissue RNA - kidney [nTPM]":"8.9","Tissue RNA - liver [nTPM]":"7.5","Tissue RNA - lung [nTPM]":"7.3","Tissue RNA - lymph node [nTPM]":"9.3","Tissue RNA - medulla oblongata [nTPM]":"4.1","Tissue RNA - midbrain [nTPM]":"5.6","Tissue RNA - ovary [nTPM]":"13.6","Tissue RNA - pancreas [nTPM]":"12.9","Tissue RNA - parathyroid gland [nTPM]":"9.4","Tissue RNA - pituitary gland [nTPM]":"6.4","Tissue RNA - placenta [nTPM]":"8.6","Tissue RNA - pons [nTPM]":"3.8","Tissue RNA - prostate [nTPM]":"13.6","Tissue RNA - rectum [nTPM]":"3.6","Tissue RNA - retina [nTPM]":"4.5","Tissue RNA - salivary gland [nTPM]":"12.2","Tissue RNA - seminal vesicle [nTPM]":"10.1","Tissue RNA - skeletal muscle [nTPM]":"5.8","Tissue RNA - skin 1 [nTPM]":"15.3","Tissue RNA - small intestine [nTPM]":"8.7","Tissue RNA - smooth muscle [nTPM]":"5.2","Tissue RNA - spinal cord [nTPM]":"2.5","Tissue RNA - spleen [nTPM]":"10.1","Tissue RNA - stomach 1 [nTPM]":"86.7","Tissue RNA - testis [nTPM]":"6.7","Tissue RNA - thalamus [nTPM]":"7.0","Tissue RNA - thymus [nTPM]":"8.6","Tissue RNA - thyroid gland [nTPM]":"9.3","Tissue RNA - tongue [nTPM]":"2.4","Tissue RNA - tonsil [nTPM]":"4.0","Tissue RNA - urinary bladder [nTPM]":"12.0","Tissue RNA - vagina [nTPM]":"10.9","Tissue RNA - white matter [nTPM]":"5.3","Cell RNA - A-431 [nTPM]":"21.1","Cell RNA - A549 [nTPM]":"26.2","Cell RNA - AF22 [nTPM]":"7.0","Cell RNA - AN3-CA [nTPM]":"5.9","Cell RNA - ASC diff [nTPM]":"9.7","Cell RNA - ASC TERT1 [nTPM]":"9.4","Cell RNA - BEWO [nTPM]":"18.4","Cell RNA - BJ [nTPM]":"19.3","Cell RNA - BJ hTERT+ [nTPM]":"17.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.1","Cell RNA - CACO-2 [nTPM]":"28.3","Cell RNA - CAPAN-2 [nTPM]":"15.5","Cell RNA - Daudi [nTPM]":"10.9","Cell RNA - EFO-21 [nTPM]":"47.6","Cell RNA - fHDF\/TERT166 [nTPM]":"17.3","Cell RNA - GAMG [nTPM]":"14.9","Cell RNA - HaCaT [nTPM]":"15.8","Cell RNA - HAP1 [nTPM]":"2.4","Cell RNA - HBEC3-KT [nTPM]":"27.0","Cell RNA - HBF TERT88 [nTPM]":"3.7","Cell RNA - HDLM-2 [nTPM]":"54.3","Cell RNA - HEK 293 [nTPM]":"18.5","Cell RNA - HEL [nTPM]":"24.6","Cell RNA - HeLa [nTPM]":"8.6","Cell RNA - Hep G2 [nTPM]":"12.4","Cell RNA - HHSteC [nTPM]":"13.3","Cell RNA - HL-60 [nTPM]":"7.8","Cell RNA - HMC-1 [nTPM]":"12.5","Cell RNA - HSkMC [nTPM]":"12.8","Cell RNA - hTCEpi [nTPM]":"16.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.6","Cell RNA - hTERT-HME1 [nTPM]":"6.3","Cell RNA - hTERT-RPE1 [nTPM]":"16.9","Cell RNA - HUVEC TERT2 [nTPM]":"14.9","Cell RNA - JURKAT [nTPM]":"9.4","Cell RNA - K-562 [nTPM]":"4.4","Cell RNA - Karpas-707 [nTPM]":"8.8","Cell RNA - LHCN-M2 [nTPM]":"11.3","Cell RNA - MCF7 [nTPM]":"27.5","Cell RNA - MOLT-4 [nTPM]":"14.4","Cell RNA - NB-4 [nTPM]":"10.7","Cell RNA - NTERA-2 [nTPM]":"6.5","Cell RNA - OE19 [nTPM]":"14.0","Cell RNA - PC-3 [nTPM]":"18.0","Cell RNA - REH [nTPM]":"7.2","Cell RNA - RH-30 [nTPM]":"20.4","Cell RNA - RPMI-8226 [nTPM]":"9.0","Cell RNA - RPTEC TERT1 [nTPM]":"9.5","Cell RNA - RT4 [nTPM]":"10.8","Cell RNA - SCLC-21H [nTPM]":"3.6","Cell RNA - SH-SY5Y [nTPM]":"9.0","Cell RNA - SiHa [nTPM]":"12.9","Cell RNA - SK-BR-3 [nTPM]":"11.9","Cell RNA - SK-MEL-30 [nTPM]":"20.3","Cell RNA - SuSa [nTPM]":"8.0","Cell RNA - T-47d [nTPM]":"57.4","Cell RNA - THP-1 [nTPM]":"7.5","Cell RNA - TIME [nTPM]":"17.4","Cell RNA - U-138 MG [nTPM]":"38.4","Cell RNA - U-2 OS [nTPM]":"19.2","Cell RNA - U-2197 [nTPM]":"20.9","Cell RNA - U-251 MG [nTPM]":"17.3","Cell RNA - U-266\/70 [nTPM]":"48.0","Cell RNA - U-266\/84 [nTPM]":"23.6","Cell RNA - U-698 [nTPM]":"3.9","Cell RNA - U-87 MG [nTPM]":"40.4","Cell RNA - U-937 [nTPM]":"12.3","Cell RNA - WM-115 [nTPM]":"10.6","Blood RNA - basophil [nTPM]":"3.7","Blood RNA - classical monocyte [nTPM]":"2.0","Blood RNA - eosinophil [nTPM]":"1.5","Blood RNA - gdT-cell [nTPM]":"2.7","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"2.7","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"2.7","Blood RNA - memory CD8 T-cell [nTPM]":"3.6","Blood RNA - myeloid DC [nTPM]":"2.4","Blood RNA - naive B-cell [nTPM]":"2.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.7","Blood RNA - naive CD8 T-cell [nTPM]":"2.5","Blood RNA - neutrophil [nTPM]":"1.9","Blood RNA - NK-cell [nTPM]":"3.6","Blood RNA - non-classical monocyte [nTPM]":"1.1","Blood RNA - plasmacytoid DC [nTPM]":"1.6","Blood RNA - T-reg [nTPM]":"2.5","Blood RNA - total PBMC [nTPM]":"2.9","Brain RNA - amygdala [nTPM]":"4.9","Brain RNA - basal ganglia [nTPM]":"5.2","Brain RNA - cerebellum [nTPM]":"8.0","Brain RNA - cerebral cortex [nTPM]":"8.2","Brain RNA - hippocampal formation [nTPM]":"5.6","Brain RNA - hypothalamus [nTPM]":"3.0","Brain RNA - medulla oblongata [nTPM]":"4.1","Brain RNA - midbrain [nTPM]":"5.6","Brain RNA - pons [nTPM]":"3.8","Brain RNA - spinal cord [nTPM]":"2.5","Brain RNA - thalamus [nTPM]":"7.0","Brain RNA - white matter [nTPM]":"5.3","Single Cell Type RNA - Adipocytes [nTPM]":"7.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.1","Single Cell Type RNA - Astrocytes [nTPM]":"13.1","Single Cell Type RNA - B-cells [nTPM]":"3.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"8.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"4.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.0","Single Cell Type RNA - dendritic cells [nTPM]":"3.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"7.1","Single Cell Type RNA - Early spermatids [nTPM]":"316.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.7","Single Cell Type RNA - Endothelial cells [nTPM]":"6.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.4","Single Cell Type RNA - Fibroblasts [nTPM]":"9.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.8","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"9.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.4","Single Cell Type RNA - Hepatocytes [nTPM]":"8.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.6","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.4","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"6.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.4","Single Cell Type RNA - Late spermatids [nTPM]":"91.4","Single Cell Type RNA - Leydig cells [nTPM]":"12.5","Single Cell Type RNA - Macrophages [nTPM]":"3.8","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"2.7","Single Cell Type RNA - Muller glia cells [nTPM]":"5.9","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.8","Single Cell Type RNA - Paneth cells [nTPM]":"3.5","Single Cell Type RNA - Peritubular cells [nTPM]":"17.3","Single Cell Type RNA - Plasma cells [nTPM]":"4.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.1","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.7","Single Cell Type RNA - Spermatocytes [nTPM]":"2.4","Single Cell Type RNA - Spermatogonia [nTPM]":"4.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - T-cells [nTPM]":"4.8","Single Cell Type RNA - Theca cells [nTPM]":"5.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.1","Single Cell Type RNA - Urothelial cells [nTPM]":"1.4"},{"Gene":"YARS1","Gene synonym":["tyrRS","YARS","YRS","YTS"],"Ensembl":"ENSG00000134684","Gene description":"Tyrosyl-tRNA synthetase 1","Uniprot":["P54577"],"Chromosome":"1","Position":"32775237-32817380","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase","RNA-binding","tRNA-binding"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"17.5","Cytotrophoblasts":"41.8","Extravillous trophoblasts":"48.1","Hofbauer cells":"41.0","Syncytiotrophoblasts":"37.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017936","HPA018950","HPA018954"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1400000","Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA017936":"AB_1858916","HPA018950":"AB_1858919","HPA018954":"AB_1858915"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.97e-11"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.02e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.57e-4"},"Tissue RNA - adipose tissue [nTPM]":"24.9","Tissue RNA - adrenal gland [nTPM]":"40.3","Tissue RNA - amygdala [nTPM]":"39.9","Tissue RNA - appendix [nTPM]":"35.0","Tissue RNA - basal ganglia [nTPM]":"51.2","Tissue RNA - bone marrow [nTPM]":"19.9","Tissue RNA - breast [nTPM]":"21.3","Tissue RNA - cerebellum [nTPM]":"38.1","Tissue RNA - cerebral cortex [nTPM]":"60.4","Tissue RNA - cervix [nTPM]":"20.5","Tissue RNA - choroid plexus [nTPM]":"30.1","Tissue RNA - colon [nTPM]":"27.5","Tissue RNA - duodenum [nTPM]":"26.0","Tissue RNA - endometrium 1 [nTPM]":"16.9","Tissue RNA - epididymis [nTPM]":"25.0","Tissue RNA - esophagus [nTPM]":"34.4","Tissue RNA - fallopian tube [nTPM]":"21.6","Tissue RNA - gallbladder [nTPM]":"15.3","Tissue RNA - heart muscle [nTPM]":"22.4","Tissue RNA - hippocampal formation [nTPM]":"42.1","Tissue RNA - hypothalamus [nTPM]":"46.6","Tissue RNA - kidney [nTPM]":"20.6","Tissue RNA - liver [nTPM]":"47.7","Tissue RNA - lung [nTPM]":"27.8","Tissue RNA - lymph node [nTPM]":"38.2","Tissue RNA - medulla oblongata [nTPM]":"37.5","Tissue RNA - midbrain [nTPM]":"38.4","Tissue RNA - ovary [nTPM]":"15.1","Tissue RNA - pancreas [nTPM]":"85.6","Tissue RNA - parathyroid gland [nTPM]":"34.1","Tissue RNA - pituitary gland [nTPM]":"14.8","Tissue RNA - placenta [nTPM]":"26.2","Tissue RNA - pons [nTPM]":"42.3","Tissue RNA - prostate [nTPM]":"18.8","Tissue RNA - rectum [nTPM]":"32.4","Tissue RNA - retina [nTPM]":"38.0","Tissue RNA - salivary gland [nTPM]":"29.6","Tissue RNA - seminal vesicle [nTPM]":"29.0","Tissue RNA - skeletal muscle [nTPM]":"31.9","Tissue RNA - skin 1 [nTPM]":"26.0","Tissue RNA - small intestine [nTPM]":"21.6","Tissue RNA - smooth muscle [nTPM]":"35.4","Tissue RNA - spinal cord [nTPM]":"38.5","Tissue RNA - spleen [nTPM]":"22.0","Tissue RNA - stomach 1 [nTPM]":"40.8","Tissue RNA - testis [nTPM]":"31.2","Tissue RNA - thalamus [nTPM]":"44.2","Tissue RNA - thymus [nTPM]":"34.6","Tissue RNA - thyroid gland [nTPM]":"42.3","Tissue RNA - tongue [nTPM]":"36.6","Tissue RNA - tonsil [nTPM]":"50.0","Tissue RNA - urinary bladder [nTPM]":"34.6","Tissue RNA - vagina [nTPM]":"14.0","Tissue RNA - white matter [nTPM]":"49.6","Cell RNA - A-431 [nTPM]":"157.1","Cell RNA - A549 [nTPM]":"92.1","Cell RNA - AF22 [nTPM]":"86.1","Cell RNA - AN3-CA [nTPM]":"194.5","Cell RNA - ASC diff [nTPM]":"111.2","Cell RNA - ASC TERT1 [nTPM]":"117.7","Cell RNA - BEWO [nTPM]":"91.7","Cell RNA - BJ [nTPM]":"151.0","Cell RNA - BJ hTERT+ [nTPM]":"136.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"133.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"165.0","Cell RNA - CACO-2 [nTPM]":"116.6","Cell RNA - CAPAN-2 [nTPM]":"103.0","Cell RNA - Daudi [nTPM]":"287.5","Cell RNA - EFO-21 [nTPM]":"63.1","Cell RNA - fHDF\/TERT166 [nTPM]":"173.2","Cell RNA - GAMG [nTPM]":"112.7","Cell RNA - HaCaT [nTPM]":"90.8","Cell RNA - HAP1 [nTPM]":"269.0","Cell RNA - HBEC3-KT [nTPM]":"204.4","Cell RNA - HBF TERT88 [nTPM]":"198.9","Cell RNA - HDLM-2 [nTPM]":"122.6","Cell RNA - HEK 293 [nTPM]":"113.9","Cell RNA - HEL [nTPM]":"254.2","Cell RNA - HeLa [nTPM]":"117.2","Cell RNA - Hep G2 [nTPM]":"114.2","Cell RNA - HHSteC [nTPM]":"383.4","Cell RNA - HL-60 [nTPM]":"202.9","Cell RNA - HMC-1 [nTPM]":"147.3","Cell RNA - HSkMC [nTPM]":"129.0","Cell RNA - hTCEpi [nTPM]":"252.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"212.7","Cell RNA - hTERT-HME1 [nTPM]":"544.2","Cell RNA - hTERT-RPE1 [nTPM]":"98.3","Cell RNA - HUVEC TERT2 [nTPM]":"140.9","Cell RNA - JURKAT [nTPM]":"245.8","Cell RNA - K-562 [nTPM]":"291.8","Cell RNA - Karpas-707 [nTPM]":"268.7","Cell RNA - LHCN-M2 [nTPM]":"117.8","Cell RNA - MCF7 [nTPM]":"107.8","Cell RNA - MOLT-4 [nTPM]":"233.0","Cell RNA - NB-4 [nTPM]":"159.3","Cell RNA - NTERA-2 [nTPM]":"149.1","Cell RNA - OE19 [nTPM]":"185.3","Cell RNA - PC-3 [nTPM]":"134.5","Cell RNA - REH [nTPM]":"198.3","Cell RNA - RH-30 [nTPM]":"75.2","Cell RNA - RPMI-8226 [nTPM]":"234.9","Cell RNA - RPTEC TERT1 [nTPM]":"109.8","Cell RNA - RT4 [nTPM]":"76.5","Cell RNA - SCLC-21H [nTPM]":"149.5","Cell RNA - SH-SY5Y [nTPM]":"94.2","Cell RNA - SiHa [nTPM]":"89.0","Cell RNA - SK-BR-3 [nTPM]":"102.7","Cell RNA - SK-MEL-30 [nTPM]":"300.8","Cell RNA - SuSa [nTPM]":"99.2","Cell RNA - T-47d [nTPM]":"95.2","Cell RNA - THP-1 [nTPM]":"247.5","Cell RNA - TIME [nTPM]":"103.6","Cell RNA - U-138 MG [nTPM]":"73.6","Cell RNA - U-2 OS [nTPM]":"135.7","Cell RNA - U-2197 [nTPM]":"152.1","Cell RNA - U-251 MG [nTPM]":"135.7","Cell RNA - U-266\/70 [nTPM]":"242.8","Cell RNA - U-266\/84 [nTPM]":"265.2","Cell RNA - U-698 [nTPM]":"255.7","Cell RNA - U-87 MG [nTPM]":"184.8","Cell RNA - U-937 [nTPM]":"297.7","Cell RNA - WM-115 [nTPM]":"203.6","Blood RNA - basophil [nTPM]":"56.1","Blood RNA - classical monocyte [nTPM]":"33.3","Blood RNA - eosinophil [nTPM]":"17.8","Blood RNA - gdT-cell [nTPM]":"59.0","Blood RNA - intermediate monocyte [nTPM]":"35.2","Blood RNA - MAIT T-cell [nTPM]":"58.4","Blood RNA - memory B-cell [nTPM]":"23.8","Blood RNA - memory CD4 T-cell [nTPM]":"35.4","Blood RNA - memory CD8 T-cell [nTPM]":"55.1","Blood RNA - myeloid DC [nTPM]":"45.8","Blood RNA - naive B-cell [nTPM]":"20.3","Blood RNA - naive CD4 T-cell [nTPM]":"25.2","Blood RNA - naive CD8 T-cell [nTPM]":"39.0","Blood RNA - neutrophil [nTPM]":"6.9","Blood RNA - NK-cell [nTPM]":"98.1","Blood RNA - non-classical monocyte [nTPM]":"35.0","Blood RNA - plasmacytoid DC [nTPM]":"26.9","Blood RNA - T-reg [nTPM]":"40.9","Blood RNA - total PBMC [nTPM]":"51.5","Brain RNA - amygdala [nTPM]":"39.9","Brain RNA - basal ganglia [nTPM]":"51.2","Brain RNA - cerebellum [nTPM]":"38.1","Brain RNA - cerebral cortex [nTPM]":"60.4","Brain RNA - hippocampal formation [nTPM]":"42.1","Brain RNA - hypothalamus [nTPM]":"46.6","Brain RNA - medulla oblongata [nTPM]":"37.5","Brain RNA - midbrain [nTPM]":"38.4","Brain RNA - pons [nTPM]":"42.3","Brain RNA - spinal cord [nTPM]":"38.5","Brain RNA - thalamus [nTPM]":"44.2","Brain RNA - white matter [nTPM]":"49.6","Single Cell Type RNA - Adipocytes [nTPM]":"7.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"41.8","Single Cell Type RNA - dendritic cells [nTPM]":"11.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"2.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"48.1","Single Cell Type RNA - Fibroblasts [nTPM]":"6.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"41.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"6.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"37.6","Single Cell Type RNA - T-cells [nTPM]":"1.4","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"YARS2","Gene synonym":["CGI-04","FLJ13995","mt-TyrRS"],"Ensembl":"ENSG00000139131","Gene description":"Tyrosyl-tRNA synthetase 2","Uniprot":["Q9Y2Z4"],"Chromosome":"12","Position":"32727490-32755897","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038721","HPA057610","HPA074097"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA038721":"AB_10674837","HPA057610":"AB_2683483","HPA074097":"AB_2686660"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.19e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.1","Tissue RNA - adrenal gland [nTPM]":"6.0","Tissue RNA - amygdala [nTPM]":"4.1","Tissue RNA - appendix [nTPM]":"6.5","Tissue RNA - basal ganglia [nTPM]":"3.8","Tissue RNA - bone marrow [nTPM]":"7.8","Tissue RNA - breast [nTPM]":"6.6","Tissue RNA - cerebellum [nTPM]":"4.3","Tissue RNA - cerebral cortex [nTPM]":"4.5","Tissue RNA - cervix [nTPM]":"5.9","Tissue RNA - choroid plexus [nTPM]":"3.9","Tissue RNA - colon [nTPM]":"5.8","Tissue RNA - duodenum [nTPM]":"4.8","Tissue RNA - endometrium 1 [nTPM]":"5.8","Tissue RNA - epididymis [nTPM]":"5.0","Tissue RNA - esophagus [nTPM]":"7.1","Tissue RNA - fallopian tube [nTPM]":"5.2","Tissue RNA - gallbladder [nTPM]":"4.4","Tissue RNA - heart muscle [nTPM]":"6.2","Tissue RNA - hippocampal formation [nTPM]":"3.9","Tissue RNA - hypothalamus [nTPM]":"3.3","Tissue RNA - kidney [nTPM]":"4.8","Tissue RNA - liver [nTPM]":"6.0","Tissue RNA - lung [nTPM]":"4.3","Tissue RNA - lymph node [nTPM]":"8.1","Tissue RNA - medulla oblongata [nTPM]":"3.7","Tissue RNA - midbrain [nTPM]":"3.0","Tissue RNA - ovary [nTPM]":"6.1","Tissue RNA - pancreas [nTPM]":"5.8","Tissue RNA - parathyroid gland [nTPM]":"6.5","Tissue RNA - pituitary gland [nTPM]":"3.7","Tissue RNA - placenta [nTPM]":"7.8","Tissue RNA - pons [nTPM]":"4.3","Tissue RNA - prostate [nTPM]":"4.6","Tissue RNA - rectum [nTPM]":"6.4","Tissue RNA - retina [nTPM]":"4.6","Tissue RNA - salivary gland [nTPM]":"8.1","Tissue RNA - seminal vesicle [nTPM]":"4.5","Tissue RNA - skeletal muscle [nTPM]":"7.3","Tissue RNA - skin 1 [nTPM]":"5.4","Tissue RNA - small intestine [nTPM]":"5.2","Tissue RNA - smooth muscle [nTPM]":"5.3","Tissue RNA - spinal cord [nTPM]":"3.1","Tissue RNA - spleen [nTPM]":"6.1","Tissue RNA - stomach 1 [nTPM]":"5.8","Tissue RNA - testis [nTPM]":"4.6","Tissue RNA - thalamus [nTPM]":"3.2","Tissue RNA - thymus [nTPM]":"7.9","Tissue RNA - thyroid gland [nTPM]":"4.6","Tissue RNA - tongue [nTPM]":"8.5","Tissue RNA - tonsil [nTPM]":"8.3","Tissue RNA - urinary bladder [nTPM]":"7.4","Tissue RNA - vagina [nTPM]":"5.1","Tissue RNA - white matter [nTPM]":"4.3","Cell RNA - A-431 [nTPM]":"19.8","Cell RNA - A549 [nTPM]":"23.3","Cell RNA - AF22 [nTPM]":"13.3","Cell RNA - AN3-CA [nTPM]":"15.8","Cell RNA - ASC diff [nTPM]":"14.3","Cell RNA - ASC TERT1 [nTPM]":"16.6","Cell RNA - BEWO [nTPM]":"42.0","Cell RNA - BJ [nTPM]":"14.8","Cell RNA - BJ hTERT+ [nTPM]":"15.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.4","Cell RNA - CACO-2 [nTPM]":"58.8","Cell RNA - CAPAN-2 [nTPM]":"24.6","Cell RNA - Daudi [nTPM]":"35.4","Cell RNA - EFO-21 [nTPM]":"23.6","Cell RNA - fHDF\/TERT166 [nTPM]":"15.0","Cell RNA - GAMG [nTPM]":"25.8","Cell RNA - HaCaT [nTPM]":"24.9","Cell RNA - HAP1 [nTPM]":"26.7","Cell RNA - HBEC3-KT [nTPM]":"38.9","Cell RNA - HBF TERT88 [nTPM]":"20.0","Cell RNA - HDLM-2 [nTPM]":"15.5","Cell RNA - HEK 293 [nTPM]":"41.8","Cell RNA - HEL [nTPM]":"23.6","Cell RNA - HeLa [nTPM]":"16.4","Cell RNA - Hep G2 [nTPM]":"33.0","Cell RNA - HHSteC [nTPM]":"20.6","Cell RNA - HL-60 [nTPM]":"25.3","Cell RNA - HMC-1 [nTPM]":"13.2","Cell RNA - HSkMC [nTPM]":"15.6","Cell RNA - hTCEpi [nTPM]":"24.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.9","Cell RNA - hTERT-HME1 [nTPM]":"30.5","Cell RNA - hTERT-RPE1 [nTPM]":"23.0","Cell RNA - HUVEC TERT2 [nTPM]":"28.5","Cell RNA - JURKAT [nTPM]":"18.4","Cell RNA - K-562 [nTPM]":"33.7","Cell RNA - Karpas-707 [nTPM]":"15.9","Cell RNA - LHCN-M2 [nTPM]":"19.1","Cell RNA - MCF7 [nTPM]":"16.1","Cell RNA - MOLT-4 [nTPM]":"18.9","Cell RNA - NB-4 [nTPM]":"30.4","Cell RNA - NTERA-2 [nTPM]":"73.5","Cell RNA - OE19 [nTPM]":"13.0","Cell RNA - PC-3 [nTPM]":"28.2","Cell RNA - REH [nTPM]":"21.0","Cell RNA - RH-30 [nTPM]":"28.4","Cell RNA - RPMI-8226 [nTPM]":"21.1","Cell RNA - RPTEC TERT1 [nTPM]":"22.9","Cell RNA - RT4 [nTPM]":"27.8","Cell RNA - SCLC-21H [nTPM]":"20.5","Cell RNA - SH-SY5Y [nTPM]":"10.0","Cell RNA - SiHa [nTPM]":"22.7","Cell RNA - SK-BR-3 [nTPM]":"19.5","Cell RNA - SK-MEL-30 [nTPM]":"14.7","Cell RNA - SuSa [nTPM]":"51.5","Cell RNA - T-47d [nTPM]":"36.5","Cell RNA - THP-1 [nTPM]":"22.7","Cell RNA - TIME [nTPM]":"19.5","Cell RNA - U-138 MG [nTPM]":"16.9","Cell RNA - U-2 OS [nTPM]":"17.7","Cell RNA - U-2197 [nTPM]":"27.8","Cell RNA - U-251 MG [nTPM]":"25.3","Cell RNA - U-266\/70 [nTPM]":"9.4","Cell RNA - U-266\/84 [nTPM]":"10.7","Cell RNA - U-698 [nTPM]":"37.0","Cell RNA - U-87 MG [nTPM]":"15.7","Cell RNA - U-937 [nTPM]":"18.6","Cell RNA - WM-115 [nTPM]":"14.3","Blood RNA - basophil [nTPM]":"10.2","Blood RNA - classical monocyte [nTPM]":"6.1","Blood RNA - eosinophil [nTPM]":"3.7","Blood RNA - gdT-cell [nTPM]":"8.4","Blood RNA - intermediate monocyte [nTPM]":"8.0","Blood RNA - MAIT T-cell [nTPM]":"8.8","Blood RNA - memory B-cell [nTPM]":"7.3","Blood RNA - memory CD4 T-cell [nTPM]":"8.8","Blood RNA - memory CD8 T-cell [nTPM]":"8.7","Blood RNA - myeloid DC [nTPM]":"8.5","Blood RNA - naive B-cell [nTPM]":"9.6","Blood RNA - naive CD4 T-cell [nTPM]":"9.0","Blood RNA - naive CD8 T-cell [nTPM]":"10.5","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"11.9","Blood RNA - non-classical monocyte [nTPM]":"9.6","Blood RNA - plasmacytoid DC [nTPM]":"8.2","Blood RNA - T-reg [nTPM]":"8.4","Blood RNA - total PBMC [nTPM]":"5.1","Brain RNA - amygdala [nTPM]":"4.1","Brain RNA - basal ganglia [nTPM]":"3.8","Brain RNA - cerebellum [nTPM]":"4.3","Brain RNA - cerebral cortex [nTPM]":"4.5","Brain RNA - hippocampal formation [nTPM]":"3.9","Brain RNA - hypothalamus [nTPM]":"3.3","Brain RNA - medulla oblongata [nTPM]":"3.7","Brain RNA - midbrain [nTPM]":"3.0","Brain RNA - pons [nTPM]":"4.3","Brain RNA - spinal cord [nTPM]":"3.1","Brain RNA - thalamus [nTPM]":"3.2","Brain RNA - white matter [nTPM]":"4.3","Single Cell Type RNA - Adipocytes [nTPM]":"14.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.4","Single Cell Type RNA - Astrocytes [nTPM]":"25.5","Single Cell Type RNA - B-cells [nTPM]":"16.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"27.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"16.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"15.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"34.7","Single Cell Type RNA - dendritic cells [nTPM]":"15.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"19.9","Single Cell Type RNA - Early spermatids [nTPM]":"6.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.7","Single Cell Type RNA - Endothelial cells [nTPM]":"10.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"21.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"36.9","Single Cell Type RNA - Fibroblasts [nTPM]":"12.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.6","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"18.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"5.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.1","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"31.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.3","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"9.3","Single Cell Type RNA - Langerhans cells [nTPM]":"6.0","Single Cell Type RNA - Late spermatids [nTPM]":"4.6","Single Cell Type RNA - Leydig cells [nTPM]":"10.5","Single Cell Type RNA - Macrophages [nTPM]":"10.4","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"16.0","Single Cell Type RNA - Muller glia cells [nTPM]":"12.3","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"26.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"44.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.2","Single Cell Type RNA - Paneth cells [nTPM]":"7.6","Single Cell Type RNA - Peritubular cells [nTPM]":"8.6","Single Cell Type RNA - Plasma cells [nTPM]":"9.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.9","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.1","Single Cell Type RNA - Spermatocytes [nTPM]":"6.3","Single Cell Type RNA - Spermatogonia [nTPM]":"12.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.9","Single Cell Type RNA - T-cells [nTPM]":"13.9","Single Cell Type RNA - Theca cells [nTPM]":"24.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.8","Single Cell Type RNA - Urothelial cells [nTPM]":"12.6"},{"Gene":"YME1L1","Gene synonym":["YME1L"],"Ensembl":"ENSG00000136758","Gene description":"YME1 like 1 ATPase","Uniprot":["Q96TA2"],"Chromosome":"10","Position":"27110111-27155266","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066953"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA066953":"AB_2685753"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.25e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Tissue RNA - adipose tissue [nTPM]":"48.8","Tissue RNA - adrenal gland [nTPM]":"52.6","Tissue RNA - amygdala [nTPM]":"17.7","Tissue RNA - appendix [nTPM]":"51.7","Tissue RNA - basal ganglia [nTPM]":"18.4","Tissue RNA - bone marrow [nTPM]":"95.1","Tissue RNA - breast [nTPM]":"47.5","Tissue RNA - cerebellum [nTPM]":"23.3","Tissue RNA - cerebral cortex [nTPM]":"21.7","Tissue RNA - cervix [nTPM]":"52.4","Tissue RNA - choroid plexus [nTPM]":"36.4","Tissue RNA - colon [nTPM]":"52.2","Tissue RNA - duodenum [nTPM]":"46.0","Tissue RNA - endometrium 1 [nTPM]":"50.3","Tissue RNA - epididymis [nTPM]":"53.3","Tissue RNA - esophagus [nTPM]":"59.1","Tissue RNA - fallopian tube [nTPM]":"43.7","Tissue RNA - gallbladder [nTPM]":"46.0","Tissue RNA - heart muscle [nTPM]":"61.4","Tissue RNA - hippocampal formation [nTPM]":"17.8","Tissue RNA - hypothalamus [nTPM]":"22.7","Tissue RNA - kidney [nTPM]":"54.0","Tissue RNA - liver [nTPM]":"65.5","Tissue RNA - lung [nTPM]":"39.8","Tissue RNA - lymph node [nTPM]":"56.6","Tissue RNA - medulla oblongata [nTPM]":"18.2","Tissue RNA - midbrain [nTPM]":"22.1","Tissue RNA - ovary [nTPM]":"50.8","Tissue RNA - pancreas [nTPM]":"52.0","Tissue RNA - parathyroid gland [nTPM]":"54.5","Tissue RNA - pituitary gland [nTPM]":"33.3","Tissue RNA - placenta [nTPM]":"61.1","Tissue RNA - pons [nTPM]":"19.9","Tissue RNA - prostate [nTPM]":"48.4","Tissue RNA - rectum [nTPM]":"52.4","Tissue RNA - retina [nTPM]":"42.0","Tissue RNA - salivary gland [nTPM]":"44.7","Tissue RNA - seminal vesicle [nTPM]":"44.5","Tissue RNA - skeletal muscle [nTPM]":"111.4","Tissue RNA - skin 1 [nTPM]":"40.1","Tissue RNA - small intestine [nTPM]":"46.3","Tissue RNA - smooth muscle [nTPM]":"49.2","Tissue RNA - spinal cord [nTPM]":"16.6","Tissue RNA - spleen [nTPM]":"46.4","Tissue RNA - stomach 1 [nTPM]":"48.8","Tissue RNA - testis [nTPM]":"51.2","Tissue RNA - thalamus [nTPM]":"19.7","Tissue RNA - thymus [nTPM]":"65.9","Tissue RNA - thyroid gland [nTPM]":"62.2","Tissue RNA - tongue [nTPM]":"97.7","Tissue RNA - tonsil [nTPM]":"62.5","Tissue RNA - urinary bladder [nTPM]":"56.8","Tissue RNA - vagina [nTPM]":"35.0","Tissue RNA - white matter [nTPM]":"24.4","Cell RNA - A-431 [nTPM]":"146.6","Cell RNA - A549 [nTPM]":"105.3","Cell RNA - AF22 [nTPM]":"125.5","Cell RNA - AN3-CA [nTPM]":"62.0","Cell RNA - ASC diff [nTPM]":"118.3","Cell RNA - ASC TERT1 [nTPM]":"123.9","Cell RNA - BEWO [nTPM]":"100.7","Cell RNA - BJ [nTPM]":"143.3","Cell RNA - BJ hTERT+ [nTPM]":"79.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"139.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"157.6","Cell RNA - CACO-2 [nTPM]":"143.3","Cell RNA - CAPAN-2 [nTPM]":"171.9","Cell RNA - Daudi [nTPM]":"152.1","Cell RNA - EFO-21 [nTPM]":"90.8","Cell RNA - fHDF\/TERT166 [nTPM]":"154.8","Cell RNA - GAMG [nTPM]":"100.5","Cell RNA - HaCaT [nTPM]":"135.6","Cell RNA - HAP1 [nTPM]":"152.8","Cell RNA - HBEC3-KT [nTPM]":"122.6","Cell RNA - HBF TERT88 [nTPM]":"152.9","Cell RNA - HDLM-2 [nTPM]":"143.4","Cell RNA - HEK 293 [nTPM]":"89.0","Cell RNA - HEL [nTPM]":"144.4","Cell RNA - HeLa [nTPM]":"91.0","Cell RNA - Hep G2 [nTPM]":"98.3","Cell RNA - HHSteC [nTPM]":"124.6","Cell RNA - HL-60 [nTPM]":"100.4","Cell RNA - HMC-1 [nTPM]":"114.5","Cell RNA - HSkMC [nTPM]":"104.7","Cell RNA - hTCEpi [nTPM]":"143.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"123.4","Cell RNA - hTERT-HME1 [nTPM]":"121.6","Cell RNA - hTERT-RPE1 [nTPM]":"122.5","Cell RNA - HUVEC TERT2 [nTPM]":"146.7","Cell RNA - JURKAT [nTPM]":"138.8","Cell RNA - K-562 [nTPM]":"173.8","Cell RNA - Karpas-707 [nTPM]":"150.5","Cell RNA - LHCN-M2 [nTPM]":"154.4","Cell RNA - MCF7 [nTPM]":"95.1","Cell RNA - MOLT-4 [nTPM]":"189.1","Cell RNA - NB-4 [nTPM]":"53.7","Cell RNA - NTERA-2 [nTPM]":"97.4","Cell RNA - OE19 [nTPM]":"119.3","Cell RNA - PC-3 [nTPM]":"49.4","Cell RNA - REH [nTPM]":"160.4","Cell RNA - RH-30 [nTPM]":"199.7","Cell RNA - RPMI-8226 [nTPM]":"143.0","Cell RNA - RPTEC TERT1 [nTPM]":"107.7","Cell RNA - RT4 [nTPM]":"68.2","Cell RNA - SCLC-21H [nTPM]":"95.6","Cell RNA - SH-SY5Y [nTPM]":"121.9","Cell RNA - SiHa [nTPM]":"138.4","Cell RNA - SK-BR-3 [nTPM]":"105.2","Cell RNA - SK-MEL-30 [nTPM]":"138.9","Cell RNA - SuSa [nTPM]":"102.8","Cell RNA - T-47d [nTPM]":"101.5","Cell RNA - THP-1 [nTPM]":"115.1","Cell RNA - TIME [nTPM]":"146.9","Cell RNA - U-138 MG [nTPM]":"83.4","Cell RNA - U-2 OS [nTPM]":"117.3","Cell RNA - U-2197 [nTPM]":"140.8","Cell RNA - U-251 MG [nTPM]":"126.7","Cell RNA - U-266\/70 [nTPM]":"75.1","Cell RNA - U-266\/84 [nTPM]":"121.9","Cell RNA - U-698 [nTPM]":"196.1","Cell RNA - U-87 MG [nTPM]":"119.4","Cell RNA - U-937 [nTPM]":"178.8","Cell RNA - WM-115 [nTPM]":"65.8","Blood RNA - basophil [nTPM]":"195.0","Blood RNA - classical monocyte [nTPM]":"146.4","Blood RNA - eosinophil [nTPM]":"165.4","Blood RNA - gdT-cell [nTPM]":"147.5","Blood RNA - intermediate monocyte [nTPM]":"128.5","Blood RNA - MAIT T-cell [nTPM]":"149.4","Blood RNA - memory B-cell [nTPM]":"143.0","Blood RNA - memory CD4 T-cell [nTPM]":"142.4","Blood RNA - memory CD8 T-cell [nTPM]":"138.8","Blood RNA - myeloid DC [nTPM]":"121.9","Blood RNA - naive B-cell [nTPM]":"149.7","Blood RNA - naive CD4 T-cell [nTPM]":"129.3","Blood RNA - naive CD8 T-cell [nTPM]":"136.8","Blood RNA - neutrophil [nTPM]":"204.0","Blood RNA - NK-cell [nTPM]":"135.6","Blood RNA - non-classical monocyte [nTPM]":"143.1","Blood RNA - plasmacytoid DC [nTPM]":"222.6","Blood RNA - T-reg [nTPM]":"156.7","Blood RNA - total PBMC [nTPM]":"155.5","Brain RNA - amygdala [nTPM]":"17.7","Brain RNA - basal ganglia [nTPM]":"18.4","Brain RNA - cerebellum [nTPM]":"23.3","Brain RNA - cerebral cortex [nTPM]":"21.7","Brain RNA - hippocampal formation [nTPM]":"17.8","Brain RNA - hypothalamus [nTPM]":"22.7","Brain RNA - medulla oblongata [nTPM]":"18.2","Brain RNA - midbrain [nTPM]":"22.1","Brain RNA - pons [nTPM]":"19.9","Brain RNA - spinal cord [nTPM]":"16.6","Brain RNA - thalamus [nTPM]":"19.7","Brain RNA - white matter [nTPM]":"24.4","Single Cell Type RNA - Adipocytes [nTPM]":"105.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"67.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"81.8","Single Cell Type RNA - Astrocytes [nTPM]":"40.5","Single Cell Type RNA - B-cells [nTPM]":"108.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"70.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"96.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"55.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"92.2","Single Cell Type RNA - Bipolar cells [nTPM]":"53.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"76.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"90.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"103.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"66.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"83.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"61.2","Single Cell Type RNA - dendritic cells [nTPM]":"121.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"179.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"52.2","Single Cell Type RNA - Early spermatids [nTPM]":"62.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"141.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"152.5","Single Cell Type RNA - Endothelial cells [nTPM]":"86.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"50.3","Single Cell Type RNA - Erythroid cells [nTPM]":"63.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"67.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"48.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"74.4","Single Cell Type RNA - Fibroblasts [nTPM]":"101.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"136.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"224.3","Single Cell Type RNA - granulocytes [nTPM]":"110.8","Single Cell Type RNA - Granulosa cells [nTPM]":"75.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"58.5","Single Cell Type RNA - Hepatocytes [nTPM]":"70.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"73.2","Single Cell Type RNA - Horizontal cells [nTPM]":"50.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"68.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"121.2","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"98.9","Single Cell Type RNA - Langerhans cells [nTPM]":"133.2","Single Cell Type RNA - Late spermatids [nTPM]":"27.0","Single Cell Type RNA - Leydig cells [nTPM]":"57.8","Single Cell Type RNA - Macrophages [nTPM]":"125.4","Single Cell Type RNA - Melanocytes [nTPM]":"56.9","Single Cell Type RNA - Microglial cells [nTPM]":"41.2","Single Cell Type RNA - monocytes [nTPM]":"63.7","Single Cell Type RNA - Muller glia cells [nTPM]":"63.8","Single Cell Type RNA - NK-cells [nTPM]":"47.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"66.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"75.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"66.8","Single Cell Type RNA - Paneth cells [nTPM]":"109.3","Single Cell Type RNA - Peritubular cells [nTPM]":"43.2","Single Cell Type RNA - Plasma cells [nTPM]":"93.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"83.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"156.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"47.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"70.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"65.7","Single Cell Type RNA - Sertoli cells [nTPM]":"72.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"156.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"94.5","Single Cell Type RNA - Spermatocytes [nTPM]":"143.4","Single Cell Type RNA - Spermatogonia [nTPM]":"57.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"92.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"64.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"94.8","Single Cell Type RNA - T-cells [nTPM]":"122.1","Single Cell Type RNA - Theca cells [nTPM]":"102.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"104.4","Single Cell Type RNA - Urothelial cells [nTPM]":"75.0"},{"Gene":"ZAP70","Gene synonym":["SRK","STD","ZAP-70"],"Ensembl":"ENSG00000115085","Gene description":"Zeta chain of T cell receptor associated protein kinase 70","Uniprot":["P43403"],"Chromosome":"2","Position":"97713576-97739862","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Disease variant","SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"24.8","lymphoid tissue":"79.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"dendritic cells":"101.0","NK-cells":"155.5","T-cells":"105.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"41","RNA blood cell specific nTPM":{"gdT-cell":"137.4","MAIT T-cell":"93.2","memory CD4 T-cell":"71.7","memory CD8 T-cell":"108.3","naive CD4 T-cell":"50.8","naive CD8 T-cell":"79.8","NK-cell":"112.2","T-reg":"80.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"56","RNA blood lineage specific nTPM":{"NK-cells":"112.2","T-cells":"137.4"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"JURKAT":"121.0","MOLT-4":"183.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002625","HPA003134"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"14000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002625":null,"HPA003134":"AB_1080629"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.89e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.66e-8"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.93e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.02e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-3"},"Tissue RNA - adipose tissue [nTPM]":"3.3","Tissue RNA - adrenal gland [nTPM]":"1.3","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"28.0","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"24.8","Tissue RNA - breast [nTPM]":"1.9","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"0.9","Tissue RNA - cervix [nTPM]":"1.7","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"4.0","Tissue RNA - duodenum [nTPM]":"5.8","Tissue RNA - endometrium 1 [nTPM]":"1.4","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"2.3","Tissue RNA - fallopian tube [nTPM]":"2.2","Tissue RNA - gallbladder [nTPM]":"5.4","Tissue RNA - heart muscle [nTPM]":"1.4","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.7","Tissue RNA - kidney [nTPM]":"2.8","Tissue RNA - liver [nTPM]":"3.9","Tissue RNA - lung [nTPM]":"8.7","Tissue RNA - lymph node [nTPM]":"57.0","Tissue RNA - medulla oblongata [nTPM]":"0.8","Tissue RNA - midbrain [nTPM]":"1.3","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"1.0","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"1.1","Tissue RNA - placenta [nTPM]":"0.9","Tissue RNA - pons [nTPM]":"0.7","Tissue RNA - prostate [nTPM]":"2.5","Tissue RNA - rectum [nTPM]":"1.5","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"2.3","Tissue RNA - seminal vesicle [nTPM]":"0.8","Tissue RNA - skeletal muscle [nTPM]":"2.0","Tissue RNA - skin 1 [nTPM]":"2.4","Tissue RNA - small intestine [nTPM]":"18.5","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"35.5","Tissue RNA - stomach 1 [nTPM]":"6.7","Tissue RNA - testis [nTPM]":"2.7","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"79.9","Tissue RNA - thyroid gland [nTPM]":"3.5","Tissue RNA - tongue [nTPM]":"2.8","Tissue RNA - tonsil [nTPM]":"17.7","Tissue RNA - urinary bladder [nTPM]":"4.9","Tissue RNA - vagina [nTPM]":"2.5","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"1.8","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"121.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"183.4","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"7.2","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"9.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.6","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"14.1","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"137.4","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"93.2","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"71.7","Blood RNA - memory CD8 T-cell [nTPM]":"108.3","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"1.6","Blood RNA - naive CD4 T-cell [nTPM]":"50.8","Blood RNA - naive CD8 T-cell [nTPM]":"79.8","Blood RNA - neutrophil [nTPM]":"2.2","Blood RNA - NK-cell [nTPM]":"112.2","Blood RNA - non-classical monocyte [nTPM]":"1.0","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"80.1","Blood RNA - total PBMC [nTPM]":"64.2","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"0.9","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.7","Brain RNA - medulla oblongata [nTPM]":"0.8","Brain RNA - midbrain [nTPM]":"1.3","Brain RNA - pons [nTPM]":"0.7","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"3.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"101.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"8.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"0.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.8","Single Cell Type RNA - Langerhans cells [nTPM]":"2.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"3.4","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"5.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"155.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"28.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.6","Single Cell Type RNA - Spermatocytes [nTPM]":"1.3","Single Cell Type RNA - Spermatogonia [nTPM]":"2.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"105.6","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"ZDHHC15","Gene synonym":["DHHC15","FLJ31812","MRX91"],"Ensembl":"ENSG00000102383","Gene description":"Zinc finger DHHC-type palmitoyltransferase 15","Uniprot":["Q96MV8"],"Chromosome":"X","Position":"75368427-75523502","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"18.2","Inhibitory neurons":"17.7","Oligodendrocyte precursor cells":"17.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"2.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"3.2","K-562":"2.1","LHCN-M2":"2.2","MOLT-4":"2.4","NTERA-2":"2.0","RH-30":"3.1","RPTEC TERT1":"1.7","SH-SY5Y":"2.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003618","HPA064901"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA003618":"AB_2217686","HPA064901":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-4"},"Tissue RNA - adipose tissue [nTPM]":"0.8","Tissue RNA - adrenal gland [nTPM]":"1.5","Tissue RNA - amygdala [nTPM]":"1.7","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"1.7","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"1.6","Tissue RNA - cerebellum [nTPM]":"1.8","Tissue RNA - cerebral cortex [nTPM]":"1.5","Tissue RNA - cervix [nTPM]":"1.6","Tissue RNA - choroid plexus [nTPM]":"1.3","Tissue RNA - colon [nTPM]":"1.0","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"1.9","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"0.8","Tissue RNA - fallopian tube [nTPM]":"1.2","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"1.7","Tissue RNA - hippocampal formation [nTPM]":"1.5","Tissue RNA - hypothalamus [nTPM]":"2.5","Tissue RNA - kidney [nTPM]":"1.5","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"1.2","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"2.2","Tissue RNA - midbrain [nTPM]":"2.2","Tissue RNA - ovary [nTPM]":"2.5","Tissue RNA - pancreas [nTPM]":"1.1","Tissue RNA - parathyroid gland [nTPM]":"1.1","Tissue RNA - pituitary gland [nTPM]":"1.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"2.0","Tissue RNA - prostate [nTPM]":"1.1","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"1.9","Tissue RNA - salivary gland [nTPM]":"4.5","Tissue RNA - seminal vesicle [nTPM]":"1.1","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"1.5","Tissue RNA - spinal cord [nTPM]":"1.8","Tissue RNA - spleen [nTPM]":"0.8","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"3.0","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"2.0","Tissue RNA - tongue [nTPM]":"0.5","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.7","Tissue RNA - vagina [nTPM]":"0.8","Tissue RNA - white matter [nTPM]":"2.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"1.6","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"3.2","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"1.4","Cell RNA - K-562 [nTPM]":"2.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"2.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"2.4","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"2.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"3.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"1.7","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.8","Cell RNA - SH-SY5Y [nTPM]":"2.6","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"1.6","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.7","Brain RNA - basal ganglia [nTPM]":"1.7","Brain RNA - cerebellum [nTPM]":"1.8","Brain RNA - cerebral cortex [nTPM]":"1.5","Brain RNA - hippocampal formation [nTPM]":"1.5","Brain RNA - hypothalamus [nTPM]":"2.5","Brain RNA - medulla oblongata [nTPM]":"2.2","Brain RNA - midbrain [nTPM]":"2.2","Brain RNA - pons [nTPM]":"2.0","Brain RNA - spinal cord [nTPM]":"1.8","Brain RNA - thalamus [nTPM]":"3.0","Brain RNA - white matter [nTPM]":"2.0","Single Cell Type RNA - Adipocytes [nTPM]":"2.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.1","Single Cell Type RNA - Astrocytes [nTPM]":"8.5","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"4.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.9","Single Cell Type RNA - Endothelial cells [nTPM]":"3.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"3.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"2.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"4.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.2","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"2.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"ZDHHC9","Gene synonym":["CGI-89","CXorf11","DHHC9","ZDHHC10","ZNF379","ZNF380"],"Ensembl":"ENSG00000188706","Gene description":"Zinc finger DHHC-type palmitoyltransferase 9","Uniprot":["Q9Y397"],"Chromosome":"X","Position":"129803288-129843909","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"66.0","Oligodendrocytes":"118.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031814"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Endoplasmic reticulum","Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA031814":"AB_10610700"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.77e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.64e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.45e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Tissue RNA - adipose tissue [nTPM]":"28.2","Tissue RNA - adrenal gland [nTPM]":"12.0","Tissue RNA - amygdala [nTPM]":"39.2","Tissue RNA - appendix [nTPM]":"10.2","Tissue RNA - basal ganglia [nTPM]":"66.6","Tissue RNA - bone marrow [nTPM]":"5.4","Tissue RNA - breast [nTPM]":"24.3","Tissue RNA - cerebellum [nTPM]":"46.5","Tissue RNA - cerebral cortex [nTPM]":"52.5","Tissue RNA - cervix [nTPM]":"19.1","Tissue RNA - choroid plexus [nTPM]":"23.3","Tissue RNA - colon [nTPM]":"22.0","Tissue RNA - duodenum [nTPM]":"31.6","Tissue RNA - endometrium 1 [nTPM]":"11.8","Tissue RNA - epididymis [nTPM]":"11.7","Tissue RNA - esophagus [nTPM]":"15.6","Tissue RNA - fallopian tube [nTPM]":"12.1","Tissue RNA - gallbladder [nTPM]":"15.3","Tissue RNA - heart muscle [nTPM]":"15.5","Tissue RNA - hippocampal formation [nTPM]":"39.2","Tissue RNA - hypothalamus [nTPM]":"49.0","Tissue RNA - kidney [nTPM]":"37.1","Tissue RNA - liver [nTPM]":"40.1","Tissue RNA - lung [nTPM]":"26.7","Tissue RNA - lymph node [nTPM]":"3.3","Tissue RNA - medulla oblongata [nTPM]":"60.5","Tissue RNA - midbrain [nTPM]":"58.2","Tissue RNA - ovary [nTPM]":"11.2","Tissue RNA - pancreas [nTPM]":"25.9","Tissue RNA - parathyroid gland [nTPM]":"25.2","Tissue RNA - pituitary gland [nTPM]":"11.4","Tissue RNA - placenta [nTPM]":"17.2","Tissue RNA - pons [nTPM]":"52.5","Tissue RNA - prostate [nTPM]":"18.8","Tissue RNA - rectum [nTPM]":"24.9","Tissue RNA - retina [nTPM]":"6.0","Tissue RNA - salivary gland [nTPM]":"21.1","Tissue RNA - seminal vesicle [nTPM]":"11.3","Tissue RNA - skeletal muscle [nTPM]":"13.4","Tissue RNA - skin 1 [nTPM]":"35.3","Tissue RNA - small intestine [nTPM]":"34.0","Tissue RNA - smooth muscle [nTPM]":"15.3","Tissue RNA - spinal cord [nTPM]":"44.8","Tissue RNA - spleen [nTPM]":"3.9","Tissue RNA - stomach 1 [nTPM]":"19.5","Tissue RNA - testis [nTPM]":"4.1","Tissue RNA - thalamus [nTPM]":"57.8","Tissue RNA - thymus [nTPM]":"3.6","Tissue RNA - thyroid gland [nTPM]":"13.8","Tissue RNA - tongue [nTPM]":"11.3","Tissue RNA - tonsil [nTPM]":"6.6","Tissue RNA - urinary bladder [nTPM]":"23.8","Tissue RNA - vagina [nTPM]":"14.5","Tissue RNA - white matter [nTPM]":"78.6","Cell RNA - A-431 [nTPM]":"45.9","Cell RNA - A549 [nTPM]":"23.8","Cell RNA - AF22 [nTPM]":"33.2","Cell RNA - AN3-CA [nTPM]":"67.5","Cell RNA - ASC diff [nTPM]":"112.4","Cell RNA - ASC TERT1 [nTPM]":"87.7","Cell RNA - BEWO [nTPM]":"27.0","Cell RNA - BJ [nTPM]":"44.3","Cell RNA - BJ hTERT+ [nTPM]":"50.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"26.0","Cell RNA - CACO-2 [nTPM]":"37.6","Cell RNA - CAPAN-2 [nTPM]":"58.4","Cell RNA - Daudi [nTPM]":"1.6","Cell RNA - EFO-21 [nTPM]":"73.7","Cell RNA - fHDF\/TERT166 [nTPM]":"47.6","Cell RNA - GAMG [nTPM]":"54.0","Cell RNA - HaCaT [nTPM]":"30.4","Cell RNA - HAP1 [nTPM]":"38.0","Cell RNA - HBEC3-KT [nTPM]":"44.6","Cell RNA - HBF TERT88 [nTPM]":"30.0","Cell RNA - HDLM-2 [nTPM]":"2.6","Cell RNA - HEK 293 [nTPM]":"23.7","Cell RNA - HEL [nTPM]":"9.2","Cell RNA - HeLa [nTPM]":"24.0","Cell RNA - Hep G2 [nTPM]":"50.1","Cell RNA - HHSteC [nTPM]":"44.4","Cell RNA - HL-60 [nTPM]":"6.1","Cell RNA - HMC-1 [nTPM]":"15.7","Cell RNA - HSkMC [nTPM]":"96.0","Cell RNA - hTCEpi [nTPM]":"71.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"34.0","Cell RNA - hTERT-HME1 [nTPM]":"50.1","Cell RNA - hTERT-RPE1 [nTPM]":"36.5","Cell RNA - HUVEC TERT2 [nTPM]":"39.9","Cell RNA - JURKAT [nTPM]":"15.0","Cell RNA - K-562 [nTPM]":"10.1","Cell RNA - Karpas-707 [nTPM]":"17.6","Cell RNA - LHCN-M2 [nTPM]":"34.0","Cell RNA - MCF7 [nTPM]":"40.0","Cell RNA - MOLT-4 [nTPM]":"8.8","Cell RNA - NB-4 [nTPM]":"11.4","Cell RNA - NTERA-2 [nTPM]":"18.0","Cell RNA - OE19 [nTPM]":"102.3","Cell RNA - PC-3 [nTPM]":"40.4","Cell RNA - REH [nTPM]":"8.2","Cell RNA - RH-30 [nTPM]":"21.4","Cell RNA - RPMI-8226 [nTPM]":"27.1","Cell RNA - RPTEC TERT1 [nTPM]":"30.1","Cell RNA - RT4 [nTPM]":"25.2","Cell RNA - SCLC-21H [nTPM]":"26.3","Cell RNA - SH-SY5Y [nTPM]":"22.0","Cell RNA - SiHa [nTPM]":"12.7","Cell RNA - SK-BR-3 [nTPM]":"64.7","Cell RNA - SK-MEL-30 [nTPM]":"20.5","Cell RNA - SuSa [nTPM]":"38.9","Cell RNA - T-47d [nTPM]":"27.6","Cell RNA - THP-1 [nTPM]":"10.1","Cell RNA - TIME [nTPM]":"32.8","Cell RNA - U-138 MG [nTPM]":"21.1","Cell RNA - U-2 OS [nTPM]":"7.3","Cell RNA - U-2197 [nTPM]":"50.0","Cell RNA - U-251 MG [nTPM]":"36.3","Cell RNA - U-266\/70 [nTPM]":"16.5","Cell RNA - U-266\/84 [nTPM]":"12.7","Cell RNA - U-698 [nTPM]":"5.5","Cell RNA - U-87 MG [nTPM]":"37.9","Cell RNA - U-937 [nTPM]":"25.1","Cell RNA - WM-115 [nTPM]":"10.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.2","Blood RNA - eosinophil [nTPM]":"1.8","Blood RNA - gdT-cell [nTPM]":"3.0","Blood RNA - intermediate monocyte [nTPM]":"2.0","Blood RNA - MAIT T-cell [nTPM]":"3.7","Blood RNA - memory B-cell [nTPM]":"2.7","Blood RNA - memory CD4 T-cell [nTPM]":"3.6","Blood RNA - memory CD8 T-cell [nTPM]":"2.9","Blood RNA - myeloid DC [nTPM]":"2.4","Blood RNA - naive B-cell [nTPM]":"1.5","Blood RNA - naive CD4 T-cell [nTPM]":"4.5","Blood RNA - naive CD8 T-cell [nTPM]":"2.6","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"2.5","Blood RNA - non-classical monocyte [nTPM]":"5.2","Blood RNA - plasmacytoid DC [nTPM]":"5.1","Blood RNA - T-reg [nTPM]":"1.8","Blood RNA - total PBMC [nTPM]":"2.1","Brain RNA - amygdala [nTPM]":"39.2","Brain RNA - basal ganglia [nTPM]":"66.6","Brain RNA - cerebellum [nTPM]":"46.5","Brain RNA - cerebral cortex [nTPM]":"52.5","Brain RNA - hippocampal formation [nTPM]":"39.2","Brain RNA - hypothalamus [nTPM]":"49.0","Brain RNA - medulla oblongata [nTPM]":"60.5","Brain RNA - midbrain [nTPM]":"58.2","Brain RNA - pons [nTPM]":"52.5","Brain RNA - spinal cord [nTPM]":"44.8","Brain RNA - thalamus [nTPM]":"57.8","Brain RNA - white matter [nTPM]":"78.6","Single Cell Type RNA - Adipocytes [nTPM]":"66.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"28.6","Single Cell Type RNA - Astrocytes [nTPM]":"4.6","Single Cell Type RNA - B-cells [nTPM]":"2.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Bipolar cells [nTPM]":"9.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"15.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"46.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.6","Single Cell Type RNA - dendritic cells [nTPM]":"2.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"20.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"18.6","Single Cell Type RNA - Early spermatids [nTPM]":"1.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.9","Single Cell Type RNA - Endothelial cells [nTPM]":"16.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.0","Single Cell Type RNA - Erythroid cells [nTPM]":"4.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.1","Single Cell Type RNA - Fibroblasts [nTPM]":"32.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"59.7","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"11.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"43.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.9","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.2","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"3.5","Single Cell Type RNA - Langerhans cells [nTPM]":"12.2","Single Cell Type RNA - Late spermatids [nTPM]":"2.0","Single Cell Type RNA - Leydig cells [nTPM]":"12.2","Single Cell Type RNA - Macrophages [nTPM]":"3.9","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"0.3","Single Cell Type RNA - Muller glia cells [nTPM]":"1.5","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"118.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"33.5","Single Cell Type RNA - Paneth cells [nTPM]":"14.6","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"7.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"39.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"51.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"25.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.1","Single Cell Type RNA - Spermatocytes [nTPM]":"8.4","Single Cell Type RNA - Spermatogonia [nTPM]":"8.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"19.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.3","Single Cell Type RNA - T-cells [nTPM]":"5.1","Single Cell Type RNA - Theca cells [nTPM]":"7.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"27.2","Single Cell Type RNA - Urothelial cells [nTPM]":"22.1"},{"Gene":"ZFYVE27","Gene synonym":["FLJ32919","SPG33"],"Ensembl":"ENSG00000155256","Gene description":"Zinc finger FYVE-type containing 27","Uniprot":["Q5T4F4"],"Chromosome":"10","Position":"97737121-97760907","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037523","HPA069876"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA037523":"AB_10672351","HPA069876":"AB_2686218"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.91e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.54e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.80e-4"},"Tissue RNA - adipose tissue [nTPM]":"14.4","Tissue RNA - adrenal gland [nTPM]":"27.9","Tissue RNA - amygdala [nTPM]":"33.1","Tissue RNA - appendix [nTPM]":"12.9","Tissue RNA - basal ganglia [nTPM]":"32.1","Tissue RNA - bone marrow [nTPM]":"23.2","Tissue RNA - breast [nTPM]":"15.8","Tissue RNA - cerebellum [nTPM]":"29.2","Tissue RNA - cerebral cortex [nTPM]":"35.9","Tissue RNA - cervix [nTPM]":"20.6","Tissue RNA - choroid plexus [nTPM]":"34.8","Tissue RNA - colon [nTPM]":"25.6","Tissue RNA - duodenum [nTPM]":"24.8","Tissue RNA - endometrium 1 [nTPM]":"16.5","Tissue RNA - epididymis [nTPM]":"22.9","Tissue RNA - esophagus [nTPM]":"16.5","Tissue RNA - fallopian tube [nTPM]":"20.3","Tissue RNA - gallbladder [nTPM]":"12.1","Tissue RNA - heart muscle [nTPM]":"17.8","Tissue RNA - hippocampal formation [nTPM]":"35.5","Tissue RNA - hypothalamus [nTPM]":"33.6","Tissue RNA - kidney [nTPM]":"28.3","Tissue RNA - liver [nTPM]":"32.6","Tissue RNA - lung [nTPM]":"17.7","Tissue RNA - lymph node [nTPM]":"16.1","Tissue RNA - medulla oblongata [nTPM]":"32.6","Tissue RNA - midbrain [nTPM]":"31.4","Tissue RNA - ovary [nTPM]":"25.9","Tissue RNA - pancreas [nTPM]":"23.7","Tissue RNA - parathyroid gland [nTPM]":"19.2","Tissue RNA - pituitary gland [nTPM]":"38.3","Tissue RNA - placenta [nTPM]":"9.5","Tissue RNA - pons [nTPM]":"33.2","Tissue RNA - prostate [nTPM]":"22.0","Tissue RNA - rectum [nTPM]":"16.3","Tissue RNA - retina [nTPM]":"28.4","Tissue RNA - salivary gland [nTPM]":"18.9","Tissue RNA - seminal vesicle [nTPM]":"10.3","Tissue RNA - skeletal muscle [nTPM]":"12.8","Tissue RNA - skin 1 [nTPM]":"18.2","Tissue RNA - small intestine [nTPM]":"30.6","Tissue RNA - smooth muscle [nTPM]":"8.5","Tissue RNA - spinal cord [nTPM]":"29.1","Tissue RNA - spleen [nTPM]":"29.1","Tissue RNA - stomach 1 [nTPM]":"19.8","Tissue RNA - testis [nTPM]":"23.0","Tissue RNA - thalamus [nTPM]":"33.5","Tissue RNA - thymus [nTPM]":"12.7","Tissue RNA - thyroid gland [nTPM]":"20.4","Tissue RNA - tongue [nTPM]":"5.9","Tissue RNA - tonsil [nTPM]":"13.1","Tissue RNA - urinary bladder [nTPM]":"16.8","Tissue RNA - vagina [nTPM]":"17.0","Tissue RNA - white matter [nTPM]":"32.4","Cell RNA - A-431 [nTPM]":"17.7","Cell RNA - A549 [nTPM]":"21.4","Cell RNA - AF22 [nTPM]":"12.6","Cell RNA - AN3-CA [nTPM]":"28.1","Cell RNA - ASC diff [nTPM]":"14.1","Cell RNA - ASC TERT1 [nTPM]":"9.8","Cell RNA - BEWO [nTPM]":"17.2","Cell RNA - BJ [nTPM]":"17.7","Cell RNA - BJ hTERT+ [nTPM]":"18.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.7","Cell RNA - CACO-2 [nTPM]":"19.1","Cell RNA - CAPAN-2 [nTPM]":"35.9","Cell RNA - Daudi [nTPM]":"27.2","Cell RNA - EFO-21 [nTPM]":"19.8","Cell RNA - fHDF\/TERT166 [nTPM]":"12.8","Cell RNA - GAMG [nTPM]":"25.9","Cell RNA - HaCaT [nTPM]":"38.8","Cell RNA - HAP1 [nTPM]":"18.4","Cell RNA - HBEC3-KT [nTPM]":"17.2","Cell RNA - HBF TERT88 [nTPM]":"10.6","Cell RNA - HDLM-2 [nTPM]":"28.3","Cell RNA - HEK 293 [nTPM]":"18.6","Cell RNA - HEL [nTPM]":"12.9","Cell RNA - HeLa [nTPM]":"23.1","Cell RNA - Hep G2 [nTPM]":"18.1","Cell RNA - HHSteC [nTPM]":"18.1","Cell RNA - HL-60 [nTPM]":"20.9","Cell RNA - HMC-1 [nTPM]":"24.9","Cell RNA - HSkMC [nTPM]":"16.0","Cell RNA - hTCEpi [nTPM]":"20.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.9","Cell RNA - hTERT-HME1 [nTPM]":"15.2","Cell RNA - hTERT-RPE1 [nTPM]":"32.4","Cell RNA - HUVEC TERT2 [nTPM]":"11.5","Cell RNA - JURKAT [nTPM]":"22.5","Cell RNA - K-562 [nTPM]":"19.6","Cell RNA - Karpas-707 [nTPM]":"17.9","Cell RNA - LHCN-M2 [nTPM]":"15.3","Cell RNA - MCF7 [nTPM]":"13.8","Cell RNA - MOLT-4 [nTPM]":"16.9","Cell RNA - NB-4 [nTPM]":"39.4","Cell RNA - NTERA-2 [nTPM]":"10.3","Cell RNA - OE19 [nTPM]":"15.3","Cell RNA - PC-3 [nTPM]":"16.4","Cell RNA - REH [nTPM]":"19.2","Cell RNA - RH-30 [nTPM]":"12.7","Cell RNA - RPMI-8226 [nTPM]":"13.0","Cell RNA - RPTEC TERT1 [nTPM]":"19.5","Cell RNA - RT4 [nTPM]":"10.8","Cell RNA - SCLC-21H [nTPM]":"10.1","Cell RNA - SH-SY5Y [nTPM]":"19.7","Cell RNA - SiHa [nTPM]":"11.9","Cell RNA - SK-BR-3 [nTPM]":"9.9","Cell RNA - SK-MEL-30 [nTPM]":"47.2","Cell RNA - SuSa [nTPM]":"11.5","Cell RNA - T-47d [nTPM]":"21.8","Cell RNA - THP-1 [nTPM]":"20.5","Cell RNA - TIME [nTPM]":"12.4","Cell RNA - U-138 MG [nTPM]":"10.2","Cell RNA - U-2 OS [nTPM]":"11.9","Cell RNA - U-2197 [nTPM]":"15.6","Cell RNA - U-251 MG [nTPM]":"34.2","Cell RNA - U-266\/70 [nTPM]":"20.6","Cell RNA - U-266\/84 [nTPM]":"18.6","Cell RNA - U-698 [nTPM]":"14.3","Cell RNA - U-87 MG [nTPM]":"25.3","Cell RNA - U-937 [nTPM]":"26.5","Cell RNA - WM-115 [nTPM]":"11.9","Blood RNA - basophil [nTPM]":"4.8","Blood RNA - classical monocyte [nTPM]":"5.8","Blood RNA - eosinophil [nTPM]":"9.3","Blood RNA - gdT-cell [nTPM]":"9.6","Blood RNA - intermediate monocyte [nTPM]":"6.2","Blood RNA - MAIT T-cell [nTPM]":"8.2","Blood RNA - memory B-cell [nTPM]":"7.1","Blood RNA - memory CD4 T-cell [nTPM]":"6.6","Blood RNA - memory CD8 T-cell [nTPM]":"7.9","Blood RNA - myeloid DC [nTPM]":"5.4","Blood RNA - naive B-cell [nTPM]":"6.7","Blood RNA - naive CD4 T-cell [nTPM]":"7.5","Blood RNA - naive CD8 T-cell [nTPM]":"8.3","Blood RNA - neutrophil [nTPM]":"8.2","Blood RNA - NK-cell [nTPM]":"6.8","Blood RNA - non-classical monocyte [nTPM]":"9.2","Blood RNA - plasmacytoid DC [nTPM]":"5.6","Blood RNA - T-reg [nTPM]":"9.5","Blood RNA - total PBMC [nTPM]":"8.3","Brain RNA - amygdala [nTPM]":"33.1","Brain RNA - basal ganglia [nTPM]":"32.1","Brain RNA - cerebellum [nTPM]":"29.2","Brain RNA - cerebral cortex [nTPM]":"35.9","Brain RNA - hippocampal formation [nTPM]":"35.5","Brain RNA - hypothalamus [nTPM]":"33.6","Brain RNA - medulla oblongata [nTPM]":"32.6","Brain RNA - midbrain [nTPM]":"31.4","Brain RNA - pons [nTPM]":"33.2","Brain RNA - spinal cord [nTPM]":"29.1","Brain RNA - thalamus [nTPM]":"33.5","Brain RNA - white matter [nTPM]":"32.4","Single Cell Type RNA - Adipocytes [nTPM]":"10.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.4","Single Cell Type RNA - Astrocytes [nTPM]":"14.0","Single Cell Type RNA - B-cells [nTPM]":"22.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Bipolar cells [nTPM]":"29.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"9.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"58.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.4","Single Cell Type RNA - dendritic cells [nTPM]":"21.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"33.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"14.9","Single Cell Type RNA - Early spermatids [nTPM]":"5.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.8","Single Cell Type RNA - Endothelial cells [nTPM]":"11.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.3","Single Cell Type RNA - Erythroid cells [nTPM]":"14.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"33.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.7","Single Cell Type RNA - Fibroblasts [nTPM]":"10.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.4","Single Cell Type RNA - granulocytes [nTPM]":"14.0","Single Cell Type RNA - Granulosa cells [nTPM]":"17.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.8","Single Cell Type RNA - Hepatocytes [nTPM]":"10.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.2","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"35.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.6","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"8.8","Single Cell Type RNA - Langerhans cells [nTPM]":"5.7","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"9.6","Single Cell Type RNA - Macrophages [nTPM]":"11.0","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"11.2","Single Cell Type RNA - Muller glia cells [nTPM]":"14.8","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.9","Single Cell Type RNA - Paneth cells [nTPM]":"26.1","Single Cell Type RNA - Peritubular cells [nTPM]":"9.1","Single Cell Type RNA - Plasma cells [nTPM]":"13.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"35.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"43.7","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.9","Single Cell Type RNA - Spermatocytes [nTPM]":"8.9","Single Cell Type RNA - Spermatogonia [nTPM]":"7.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"13.5","Single Cell Type RNA - T-cells [nTPM]":"17.9","Single Cell Type RNA - Theca cells [nTPM]":"10.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.7","Single Cell Type RNA - Urothelial cells [nTPM]":"17.7"},{"Gene":"ZMPSTE24","Gene synonym":["FACE-1","HGPS","PRO1","STE24","Ste24p"],"Ensembl":"ENSG00000084073","Gene description":"Zinc metallopeptidase STE24","Uniprot":["O75844"],"Chromosome":"1","Position":"40258041-40294180","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006988"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"50000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA006988":"AB_1080659"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.73e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.34e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Tissue RNA - adipose tissue [nTPM]":"20.5","Tissue RNA - adrenal gland [nTPM]":"24.6","Tissue RNA - amygdala [nTPM]":"16.3","Tissue RNA - appendix [nTPM]":"19.9","Tissue RNA - basal ganglia [nTPM]":"16.7","Tissue RNA - bone marrow [nTPM]":"5.6","Tissue RNA - breast [nTPM]":"25.5","Tissue RNA - cerebellum [nTPM]":"18.1","Tissue RNA - cerebral cortex [nTPM]":"22.9","Tissue RNA - cervix [nTPM]":"26.2","Tissue RNA - choroid plexus [nTPM]":"21.9","Tissue RNA - colon [nTPM]":"28.5","Tissue RNA - duodenum [nTPM]":"22.2","Tissue RNA - endometrium 1 [nTPM]":"26.7","Tissue RNA - epididymis [nTPM]":"27.4","Tissue RNA - esophagus [nTPM]":"21.7","Tissue RNA - fallopian tube [nTPM]":"18.8","Tissue RNA - gallbladder [nTPM]":"25.7","Tissue RNA - heart muscle [nTPM]":"20.6","Tissue RNA - hippocampal formation [nTPM]":"16.1","Tissue RNA - hypothalamus [nTPM]":"18.8","Tissue RNA - kidney [nTPM]":"46.0","Tissue RNA - liver [nTPM]":"38.4","Tissue RNA - lung [nTPM]":"21.7","Tissue RNA - lymph node [nTPM]":"16.8","Tissue RNA - medulla oblongata [nTPM]":"17.4","Tissue RNA - midbrain [nTPM]":"17.7","Tissue RNA - ovary [nTPM]":"14.3","Tissue RNA - pancreas [nTPM]":"17.4","Tissue RNA - parathyroid gland [nTPM]":"53.3","Tissue RNA - pituitary gland [nTPM]":"10.2","Tissue RNA - placenta [nTPM]":"22.1","Tissue RNA - pons [nTPM]":"18.5","Tissue RNA - prostate [nTPM]":"26.3","Tissue RNA - rectum [nTPM]":"33.1","Tissue RNA - retina [nTPM]":"10.9","Tissue RNA - salivary gland [nTPM]":"19.6","Tissue RNA - seminal vesicle [nTPM]":"23.8","Tissue RNA - skeletal muscle [nTPM]":"16.3","Tissue RNA - skin 1 [nTPM]":"16.3","Tissue RNA - small intestine [nTPM]":"23.4","Tissue RNA - smooth muscle [nTPM]":"32.2","Tissue RNA - spinal cord [nTPM]":"18.7","Tissue RNA - spleen [nTPM]":"13.7","Tissue RNA - stomach 1 [nTPM]":"21.3","Tissue RNA - testis [nTPM]":"11.0","Tissue RNA - thalamus [nTPM]":"17.7","Tissue RNA - thymus [nTPM]":"15.5","Tissue RNA - thyroid gland [nTPM]":"27.5","Tissue RNA - tongue [nTPM]":"18.1","Tissue RNA - tonsil [nTPM]":"23.0","Tissue RNA - urinary bladder [nTPM]":"29.4","Tissue RNA - vagina [nTPM]":"16.2","Tissue RNA - white matter [nTPM]":"18.9","Cell RNA - A-431 [nTPM]":"69.3","Cell RNA - A549 [nTPM]":"38.4","Cell RNA - AF22 [nTPM]":"35.6","Cell RNA - AN3-CA [nTPM]":"26.1","Cell RNA - ASC diff [nTPM]":"90.3","Cell RNA - ASC TERT1 [nTPM]":"71.3","Cell RNA - BEWO [nTPM]":"67.0","Cell RNA - BJ [nTPM]":"64.0","Cell RNA - BJ hTERT+ [nTPM]":"60.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"81.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"73.9","Cell RNA - CACO-2 [nTPM]":"35.4","Cell RNA - CAPAN-2 [nTPM]":"118.8","Cell RNA - Daudi [nTPM]":"62.7","Cell RNA - EFO-21 [nTPM]":"41.1","Cell RNA - fHDF\/TERT166 [nTPM]":"92.1","Cell RNA - GAMG [nTPM]":"29.9","Cell RNA - HaCaT [nTPM]":"71.0","Cell RNA - HAP1 [nTPM]":"78.4","Cell RNA - HBEC3-KT [nTPM]":"67.9","Cell RNA - HBF TERT88 [nTPM]":"97.9","Cell RNA - HDLM-2 [nTPM]":"54.4","Cell RNA - HEK 293 [nTPM]":"39.8","Cell RNA - HEL [nTPM]":"59.9","Cell RNA - HeLa [nTPM]":"36.0","Cell RNA - Hep G2 [nTPM]":"44.5","Cell RNA - HHSteC [nTPM]":"45.4","Cell RNA - HL-60 [nTPM]":"99.3","Cell RNA - HMC-1 [nTPM]":"68.8","Cell RNA - HSkMC [nTPM]":"45.5","Cell RNA - hTCEpi [nTPM]":"67.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"64.7","Cell RNA - hTERT-HME1 [nTPM]":"28.4","Cell RNA - hTERT-RPE1 [nTPM]":"45.4","Cell RNA - HUVEC TERT2 [nTPM]":"58.3","Cell RNA - JURKAT [nTPM]":"27.3","Cell RNA - K-562 [nTPM]":"63.0","Cell RNA - Karpas-707 [nTPM]":"60.6","Cell RNA - LHCN-M2 [nTPM]":"80.1","Cell RNA - MCF7 [nTPM]":"30.2","Cell RNA - MOLT-4 [nTPM]":"60.7","Cell RNA - NB-4 [nTPM]":"28.3","Cell RNA - NTERA-2 [nTPM]":"70.0","Cell RNA - OE19 [nTPM]":"47.2","Cell RNA - PC-3 [nTPM]":"42.2","Cell RNA - REH [nTPM]":"52.2","Cell RNA - RH-30 [nTPM]":"60.2","Cell RNA - RPMI-8226 [nTPM]":"77.6","Cell RNA - RPTEC TERT1 [nTPM]":"75.2","Cell RNA - RT4 [nTPM]":"58.0","Cell RNA - SCLC-21H [nTPM]":"38.0","Cell RNA - SH-SY5Y [nTPM]":"44.6","Cell RNA - SiHa [nTPM]":"60.9","Cell RNA - SK-BR-3 [nTPM]":"155.6","Cell RNA - SK-MEL-30 [nTPM]":"85.9","Cell RNA - SuSa [nTPM]":"56.3","Cell RNA - T-47d [nTPM]":"55.2","Cell RNA - THP-1 [nTPM]":"249.1","Cell RNA - TIME [nTPM]":"46.4","Cell RNA - U-138 MG [nTPM]":"68.6","Cell RNA - U-2 OS [nTPM]":"52.5","Cell RNA - U-2197 [nTPM]":"56.0","Cell RNA - U-251 MG [nTPM]":"78.0","Cell RNA - U-266\/70 [nTPM]":"37.1","Cell RNA - U-266\/84 [nTPM]":"106.2","Cell RNA - U-698 [nTPM]":"49.6","Cell RNA - U-87 MG [nTPM]":"75.6","Cell RNA - U-937 [nTPM]":"64.6","Cell RNA - WM-115 [nTPM]":"79.1","Blood RNA - basophil [nTPM]":"18.9","Blood RNA - classical monocyte [nTPM]":"21.4","Blood RNA - eosinophil [nTPM]":"14.0","Blood RNA - gdT-cell [nTPM]":"17.6","Blood RNA - intermediate monocyte [nTPM]":"27.2","Blood RNA - MAIT T-cell [nTPM]":"22.5","Blood RNA - memory B-cell [nTPM]":"15.0","Blood RNA - memory CD4 T-cell [nTPM]":"19.4","Blood RNA - memory CD8 T-cell [nTPM]":"19.4","Blood RNA - myeloid DC [nTPM]":"29.4","Blood RNA - naive B-cell [nTPM]":"11.4","Blood RNA - naive CD4 T-cell [nTPM]":"16.7","Blood RNA - naive CD8 T-cell [nTPM]":"22.9","Blood RNA - neutrophil [nTPM]":"8.5","Blood RNA - NK-cell [nTPM]":"29.6","Blood RNA - non-classical monocyte [nTPM]":"24.3","Blood RNA - plasmacytoid DC [nTPM]":"18.4","Blood RNA - T-reg [nTPM]":"24.6","Blood RNA - total PBMC [nTPM]":"22.7","Brain RNA - amygdala [nTPM]":"16.3","Brain RNA - basal ganglia [nTPM]":"16.7","Brain RNA - cerebellum [nTPM]":"18.1","Brain RNA - cerebral cortex [nTPM]":"22.9","Brain RNA - hippocampal formation [nTPM]":"16.1","Brain RNA - hypothalamus [nTPM]":"18.8","Brain RNA - medulla oblongata [nTPM]":"17.4","Brain RNA - midbrain [nTPM]":"17.7","Brain RNA - pons [nTPM]":"18.5","Brain RNA - spinal cord [nTPM]":"18.7","Brain RNA - thalamus [nTPM]":"17.7","Brain RNA - white matter [nTPM]":"18.9","Single Cell Type RNA - Adipocytes [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"24.1","Single Cell Type RNA - Astrocytes [nTPM]":"19.2","Single Cell Type RNA - B-cells [nTPM]":"20.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"32.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"41.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"33.0","Single Cell Type RNA - Bipolar cells [nTPM]":"6.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"35.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"19.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"54.3","Single Cell Type RNA - Club cells [nTPM]":"43.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"73.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"41.4","Single Cell Type RNA - dendritic cells [nTPM]":"22.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"31.3","Single Cell Type RNA - Ductal cells [nTPM]":"58.9","Single Cell Type RNA - Early spermatids [nTPM]":"3.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"30.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"32.6","Single Cell Type RNA - Endothelial cells [nTPM]":"31.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"27.6","Single Cell Type RNA - Erythroid cells [nTPM]":"18.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"36.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"38.3","Single Cell Type RNA - Fibroblasts [nTPM]":"36.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"40.0","Single Cell Type RNA - granulocytes [nTPM]":"21.0","Single Cell Type RNA - Granulosa cells [nTPM]":"16.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"27.5","Single Cell Type RNA - Hepatocytes [nTPM]":"64.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"34.0","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.0","Single Cell Type RNA - Ionocytes [nTPM]":"54.9","Single Cell Type RNA - Kupffer cells [nTPM]":"33.9","Single Cell Type RNA - Langerhans cells [nTPM]":"24.5","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"28.6","Single Cell Type RNA - Macrophages [nTPM]":"28.6","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"30.5","Single Cell Type RNA - Muller glia cells [nTPM]":"29.3","Single Cell Type RNA - NK-cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"44.0","Single Cell Type RNA - Paneth cells [nTPM]":"29.3","Single Cell Type RNA - Peritubular cells [nTPM]":"32.7","Single Cell Type RNA - Plasma cells [nTPM]":"31.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"37.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"31.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"42.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"64.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"26.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"41.2","Single Cell Type RNA - Spermatocytes [nTPM]":"7.8","Single Cell Type RNA - Spermatogonia [nTPM]":"6.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"31.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"39.0","Single Cell Type RNA - T-cells [nTPM]":"23.1","Single Cell Type RNA - Theca cells [nTPM]":"28.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"35.6","Single Cell Type RNA - Urothelial cells [nTPM]":"24.5"}]